FLY_GENE _SYMBOL FULL_NAME URL SECONDARY_FBGNS GENE_CLASS GO_MOLECULAR_FUNCTION GO_BIOLOGICAL_PROCESS GO_CELLULAR_COMPONENT SYNONYMS PROTEIN_DOMAINS CG_SYMBOL DATE_LAST_UPDATED DATA_VERSION ZEBRAFISH_ORTHOLOGS YEAST_ORTHOLOGS WORM_ORTHOLOGS XENOPUS_ORTHOLOGS MOUSE_ORTHOLOGS HUMAN_ORTHOLOGS RNA_EXPRESSION_STAGE RNA_EXPRESSION_TISSUE PROTEIN_EXPRESSION_STAGE PROTEIN_EXPRESSION_TISSUE FLYBASE_EXP_LINK PHENO_CLASS PHENO_MANIFEST DRSC SCREEN AVG_Z_SCORE_BASELINE_S2R AVG_Z_SCORE_10_INSULIN_S2R AVG_Z_SCORE_BASELINE_S2R_MTDER AVG_Z_SCORE_10_EGF_S2R_MTDER AVG_Z_SCORE_10_EGF_KC AVG_Z_SCORE_30_EGF_KC HUMAN_DISEASE HUMAN_ORTHOLOG_DESCRIPTION FBgn0026181 Rok Rho kinase http://flybase.org/reports/FBgn0026181 FBgn0028698 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 Rho GTPase binding ; GO:0017048 | inferred from electronic annotation with InterPro:IPR015008 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement GTPase binding ; GO:0051020 | inferred from physical interaction with Rho1 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Rho1 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity inferred from direct assay" regulation of phosphorylation ; GO:0042325 | inferred from direct assay epidermis development ; GO:0008544 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement dorsal closure ; GO:0007391 | traceable author statement regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with LIMK1 actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype regulation of planar cell polarity pathway involved in axis elongation ; GO:2000040 | inferred from direct assay establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype Rho protein signal transduction ; GO:0007266 | inferred from physical interaction with Rho1 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | traceable author statement imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype inferred from genetic interaction with dsh inferred from genetic interaction with fz actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype nuclear axial expansion ; GO:0035191 | inferred from mutant phenotype regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype cortical protein anchoring ; GO:0032065 | inferred from mutant phenotype positive regulation of stress fiber assembly ; GO:0051496 | inferred from genetic interaction with Fhos female germline ring canal stabilization ; GO:0008335 | inferred from mutant phenotype regulation of protein phosphorylation ; GO:0001932 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype oocyte axis specification ; GO:0007309 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype nurse cell nucleus anchoring ; GO:0007302 | inferred from mutant phenotype regulation of actin filament bundle assembly ; GO:0032231 | inferred from mutant phenotype inferred from genetic interaction with dsh inferred from genetic interaction with fz mitotic cytokinesis ; GO:0000281 | inferred from direct assay positive regulation of wound healing ; GO:0090303 | inferred from mutant phenotype negative regulation of response to wounding ; GO:1903035 | inferred from mutant phenotype regulation of cell junction assembly ; GO:1901888 | inferred from genetic interaction with Pten establishment of protein localization ; GO:0045184 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype regulation of myoblast fusion ; GO:1901739 | inferred from genetic interaction with Rho1 ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | non-traceable author statement apical cortex ; GO:0045179 | colocalizes_with inferred from direct assay cell-cell contact zone ; GO:0044291 | inferred from direct assay "ROCK, Drok, Rok, DROK, ROK, ROKalpha/beta, drok, Rock, RhoK, dROK, dRok, DRhk, ROCK1, CG9774, Rhk, ROCK-1, rok, DRok, Rok/ROCK, ROCK2" "IPR029875:Rho-associated protein kinase LET-502, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR001849:Pleckstrin homology domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR015008:Rho binding domain, IPR017441:Protein kinase, ATP binding site, IPR011993:PH domain-like, IPR020684:Rho-associated protein kinase 1/2" CG9774 11-Aug-17 DroID_v2017_08 "Drer\LOC101882847, Drer\rock1, Drer\rock2b, Drer\rock2a, Drer\cdc42bpb" "Scer\HSL1, Scer\CBK1" Cele\let-502 "Xtro\rock2, Xtro\rock1, Xtro\tacc3" "Mmus\Rock2, Mmus\Tacc3, Mmus\Rock1, Mmus\Cdc42bpb, Mmus\Tacc2" "Hsap\ROCK2, Hsap\CDC42BPB, Hsap\TACC3, Hsap\ROCK1" " embryonic stage , larval stage | third instar " "

ubiquitous , imaginal disc | ubiquitous

" "lethal - all die before end of pupal stage,visible,planar polarity defective,partially lethal - majority die,some die during pupal stage,wound healing defective,mitotic cell cycle defective,neuroanatomy defective,cell polarity defective,somatic clone,cell shape defective,increased cell death,wild-type,lethal,viable,recessive,female sterile,germline clone,axis specification defective,male limited,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic salivary gland,egg chamber,conditional,wing,mesothoracic tergum,S2 cell-line & spindle,S2 cell-line & cell,S2 cell-line & spindle microtubule,S2 cell-line & polar microtubule,embryonic/larval epidermis,oocyte,somatic clone,vertical lobe of adult mushroom body,nucleus,epithelial cell,eye,photoreceptor cell,crossvein,wing margin,macrophage | third instar larval stage,stress fiber | third instar larval stageHml.‘î,contractile ring | somatic clone,eye photoreceptor cell,supernumerary,ommatidium,wing hair,cell autonomous,mushroom body & axon | somatic clone,egg,germline clone,dorsal appendage,yolk granule | germline clone,nurse cell,nurse cell ring canal,filamentous actin & oocyte | germ-line clone,filamentous actin & nurse cell | germ-line clone,plasma membrane & oocyte | germ-line clone,hub cell,adherens junction | somatic clone,morphogenetic furrow,epithelium,follicle cell,anterior embryonic/larval midgut,male limited,embryonic proventriculus,embryonic/first instar larval cuticle,dorsal,dorsal hair,embryonic leading edge cell,wing disc | third instar larval stage,wing disc,somatic clone | third instar larval stage" DRSC20277 K 1.140488567 -0.484681497 -0.401458467 0.182061105 -0.607747052 -1.512870256 FBgn0000547 ed echinoid http://flybase.org/reports/FBgn0000547 "FBgn0022256, FBgn0031582, FBgn0031583, FBgn0031584" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Grip "negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype negative regulation of hippo signaling ; GO:0035331 | inferred from genetic interaction with yki inferred from genetic interaction with sav ommatidial rotation ; GO:0016318 | inferred from mutant phenotype inferred from genetic interaction with fz inferred from genetic interaction with pnt inferred from genetic interaction with stan inferred from genetic interaction with cno muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | non-traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of organ growth ; GO:0046621 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of hippo signaling ; GO:0035330 | inferred from physical interaction with ex inferred from physical interaction with sav inferred from physical interaction with Mer inferred from physical interaction with kibra homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of actin cytoskeleton organization by cell-cell adhesion ; GO:0090138 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype inferred from genetic interaction with Ras85D inferred from genetic interaction with rl inferred from genetic interaction with Egfr inferred from genetic interaction with RasGAP1 inferred from genetic interaction with aos inferred from genetic interaction with rho inferred from genetic interaction with sty branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype negative regulation of fusion cell fate specification ; GO:0035157 | inferred from mutant phenotype contractile actin filament bundle assembly ; GO:0030038 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype inferred from physical interaction with Nrg" cell-cell adherens junction ; GO:0005913 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "ed, CG16842, E(Elp)[24D], CT13476, CT35484, l(2)k01102, 1X5, E(Elp)24D, CG15424, CG12676, Ed" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold" CG12676 11-Aug-17 DroID_v2017_08 "Drer\kirrel3b, Drer\kirrela, Drer\kirrel3l, Drer\kirrel3a, Drer\tmigd1, Drer\kirrelb" - "Cele\igcm-1, Cele\F22D3.6" - "Mmus\Kirrel2, Mmus\Malt1, Mmus\Kirrel3, Mmus\Kirrel" "Hsap\KIRREL2, Hsap\KIRREL, Hsap\MALT1, Hsap\KIRREL3" "lethal,recessive,behavior defective,cell shape defective,cell autonomous,somatic clone,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,heat sensitive,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,visible,dominant,lethal - all die before end of larval stage,some die during larval stage,wild-type,viable,size defective,cell non-autonomous,wound healing defective,germline clone,cell adhesion defective" "embryonic/larval tracheal system,germline clone,rescuable maternal effect,embryo,embryonic epidermis,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,tracheal fusion cell,ectopic,wing disc,cell autonomous,somatic clone,cell non-autonomous,presumptive embryonic/larval central nervous system,embryonic neuroblast,embryonic/larval neuron,supernumerary,ventral nerve cord,macrochaeta,microchaeta,eye,wing vein L2,wing margin,distal,dorsocentral bristle,scutellar bristle,chemosensory ventral triple row & microchaeta | ectopic,dorsal triple row & microchaeta | ectopic,photoreceptor cell R8,sex comb,photoreceptor cell R7,wing,ommatidium,ommatidial precursor cluster,actomyosin | dorsal closure stagec381,epidermal cell | dorsal closure stage,eye photoreceptor cell,dorsal triple row & macrochaeta | ectopic,adult thorax & microchaeta | ectopic,embryonic/first instar larval cuticle,denticle belt,chorion | somatic clone,follicle cell,dorsal closure embryo,actin filament bundle | ectopic | somatic clone,adherens junction | somatic clone,embryonic leading edge cell & actomyosin,embryonic dorsal epidermis,embryonic segment,sensory mother cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,mystery cell,cone cell,wing vein,ventral longitudinal muscle,lateral transverse muscle,photoreceptor cell,apical plasma membrane & cell & dorsal mesothoracic disc & third instar larva | somatic clone,wing hair,wing cell,sensillum campaniformium & wing | supernumerary | somatic clone,oocyte,scutellum,dorsal appendage,actomyosin | dorsal closure stage,embryonic/larval dorsal anastomosis,posterior,chaeta,trichogen cell,mesothoracic tergum" DRSC00439 E -1.109723912 0.005681429 0.031203273 2.062307314 0.549157922 0.554889436 FBgn0030600 hiw highwire http://flybase.org/reports/FBgn0030600 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O62609 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V6L9 protein binding ; GO:0005515 | inferred from physical interaction with Rae1 inferred from physical interaction with Fsn zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with UniProtKB:Q8WY64 regulation of synaptic growth at neuromuscular junction ; GO:0008582 | traceable author statement negative regulation of BMP signaling pathway ; GO:0030514 | inferred from genetic interaction with UniProtKB:O62609 inferred from genetic interaction with UniProtKB:Q9VZI9 response to axon injury ; GO:0048678 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | non-traceable author statement protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with UniProtKB:Q8WY64 synapse organization ; GO:0050808 | inferred from direct assay regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype locomotion ; GO:0040011 | non-traceable author statement BMP signaling pathway ; GO:0030509 | inferred from physical interaction with UniProtKB:O62609 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay "CG9049, CG9041, CG32592, hiw, Hiw" "IPR000408:Regulator of chromosome condensation, RCC1, IPR001841:Zinc finger, RING-type, IPR012983:PHR, IPR008979:Galactose-binding domain-like, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR014756:Immunoglobulin E-set, IPR004939:APC10/DOC domain, IPR017868:Filamin/ABP280 repeat-like, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013783:Immunoglobulin-like fold" CG32592 11-Aug-17 DroID_v2017_08 Drer\mycbp2 - "Cele\F07B7.12, Cele\rpm-1" Xtro\mycbp2 Mmus\Mycbp2 Hsap\MYCBP2 "neuroanatomy defective,conditional,neurophysiology defective,somatic clone,decreased cell growth,recessive,locomotor behavior defective,viable" "embryonic/larval neuromuscular junction,NMJ bouton,supernumerary,synapse,neuromuscular junction | larval stage,dorsal multidendritic neuron ddaC,neuromuscular junction,indirect flight muscle motor neuron MN4,terminal bouton,segmental nerve,conditional,bouton,wing vein L1,somatic clone,terminal boutonelav.Switch.PO,neuromuscular junctionelav.Switch.PO,synapseelav.Switch.PO,indirect flight muscle motor neuron MN4 & bouton | ectopic,neuroblast,synaptic vesicle,motor neuron,giant fiber neuron,tergotrochanteral muscle motor neuron,synapseelav.Switch.PO, hiw‘îRCC1.UAS.TZzzzTAP,synapseelav.Switch.PO, hiw‘îPHR.UAS.TZzzzTAP,synapseelav.Switch.PO, hiwHindIII.UAS.TZzzzHis6,THsapMYC,synapseelav.Switch.PO, hiw‘îN.UAS.TZzzzTAP,synapseelav.Switch.PO, hiwND8,eye" FBgn0003371 sgg shaggy http://flybase.org/reports/FBgn0003371 "FBgn0026697, FBgn0026849, FBgn0027246, FBgn0028324, FBgn0029071, FBgn0066814" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O16844 protein binding ; GO:0005515 | inferred from physical interaction with Axn protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity kinase activity ; GO:0016301 | inferred from direct assay" chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | traceable author statement wing and notum subfield formation ; GO:0035309 | inferred from mutant phenotype entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype establishment of epithelial cell planar polarity ; GO:0090163 | inferred from mutant phenotype inferred from genetic interaction with aPKC pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | non-traceable author statement response to anesthetic ; GO:0072347 | inferred from mutant phenotype negative regulation of JUN kinase activity ; GO:0043508 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | traceable author statement rhythmic behavior ; GO:0007622 | traceable author statement regulation of proteolysis ; GO:0030162 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement heart development ; GO:0007507 | non-traceable author statement Wnt signaling pathway ; GO:0016055 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay circadian rhythm ; GO:0007623 | non-traceable author statement olfactory learning ; GO:0008355 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | traceable author statement ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype regulation of calcineurin-NFAT signaling cascade ; GO:0070884 | inferred from mutant phenotype epithelial cell morphogenesis ; GO:0003382 | inferred from mutant phenotype inferred from genetic interaction with aPKC regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from direct assay negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | non-traceable author statement regulation of protein import into nucleus ; GO:0042306 | traceable author statement negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from direct assay positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | non-traceable author statement synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay "GSK3, sgg, GSK3beta/SGG, Zw3, GSK, zw3, GSK3beta, Gsk3, GSK-3, GSKbeta, GSK-3beta, ZW3, CG2621, EG:155E2.3, Zw3-sh, DMSGG3, Sgg, SGG/GSK3b, Zw3/GSK3, sgg46, sgg39, sgg10, DMZ3K25Z, sgg-zw3, l(1)3Ba, zw-3, Zw-3, zw3[sgg], Zw3[sgg], zw3/sgg, sgg/zw3, zw[3], zw3(sgg), l(1)zw3, ZW-3, l(1)G0055, l(1)G0183, l(1)G0263, l(1)G0335, EG:BACR7C10.8, anon-WO03040301.254, gsk3, Dmsgg3, SGG, Sgg/Zw3/GSK3, Gsk-3, GSK-3B, GSK3betagr;, zw3/GSK3beta, Dm Zw3, GSK-3betaSgg, GSK3Beta, GSK3-beta, Gsk-3beta, GSK3A" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR033573:Glycogen synthase kinase-3 beta" CG2621 11-Aug-17 DroID_v2017_08 "Drer\gsk3aa, Drer\si:dkeyp-80c12.7, Drer\gsk3b, Drer\gsk3ab" "Scer\YGK3, Scer\MCK1, Scer\RIM11, Scer\MRK1" "Cele\C44H4.6, Cele\ire-1, Cele\gck-1, Cele\R03D7.5, Cele\gsk-3" "Xtro\gsk3a, Xtro\gsk3b" "Mmus\Gsk3b, Mmus\Gsk3a" "Hsap\GSK3B, Hsap\GSK3A, Hsap\MYLK" larval stage | third instar nerve terminal | subset

"lethal,recessive,visible,somatic clone,viable,locomotor rhythm defective,circadian rhythm defective,behavior defective,neuroanatomy defective,neurophysiology defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,maternal effect,germline clone,developmental rate defective,mitotic cell cycle defective,planar polarity defective,cell non-autonomous,cell polarity defective,lethal - all die before end of embryonic stage,some die during embryonic stage,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,non-rescuable maternal effect,some die during third instar larval stage,meiotic cell cycle defective,short lived,smell perception defective,heat sensitive,fertile,chemical sensitive" "eye,somatic clone,eye disc,macrochaeta,supernumerary,synapse,macrochaeta & wing,embryonic/larval dorsal vessel,ommatidium,embryonic/first instar larval cuticle,germline clone,maternal effect,denticle belt,embryonic head,embryonic/larval spiracle,filzkorper,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic/larval brain,wing,leg,tibia,tarsal segment,ventral thoracic disc,ventral thoracic disc & macrochaeta | somatic clone,syncytial blastoderm embryo,nucleus | embryonic stage 4 | germline clone,follicle stem cell,germline cyst,follicle cell,embryonic epidermis,dorsal,dorsal hair,embryonic Malpighian tubule,mesothoracic tarsal bristle longitudinal row 2,mesothoracic tarsal bristle longitudinal row 3,mesothoracic tarsal bristle longitudinal row 4,mesothoracic tarsal bristle longitudinal row 5,mesothoracic tarsal bristle longitudinal row 6,mesothoracic tarsal bristle longitudinal row 7,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,denticle,rescuable maternal effect,embryonic/larval somatic muscle,stomodeal invagination,midgut constriction 1,ectopic,posterior compartment,precursor,cell non-autonomous,wing margin bristle,wing vein,sensillum campaniformium,wing blade,mechanosensory ventral triple row bristle,wing sensillum,imaginal disc,egg,female reproductive system,wing hair,non-rescuable maternal effect,embryonic/larval neuromuscular junction,bouton,external sensory organ precursor cell,microchaeta,adult cuticle & abdomen | somatic clone,anterior,adult thorax & macrochaeta | somatic clone,adult thorax & microchaeta | somatic clone,cuticle,macrochaeta & wing | ectopic | somatic clone,1st axillary sclerite,2nd axillary sclerite,3rd axillary sclerite,unnamed wing hinge sclerite,axillary pouch,macrochaeta & mesothoracic tergum | somatic clone | cell autonomous,macrochaeta & scutum | somatic clone | cell autonomous,cell autonomous,macrochaeta & prescutum | somatic clone | cell autonomous,sensory mother cell,NMJ bouton,dendritic arborizing neuron | third instar larval stage,wing margin,mesothoracic tergum,morphogenetic furrow,melanotic mass,lamellocyte,crystal cell,scutellum,adult thorax & chaeta-537.4,dorsocentral bristle,posterior dorsocentral bristle,bouton | larval stage,scutellar bristle,wing disc,adult thorax & microchaeta-537.4,synapse796,antennal lobe,synapseGH298,intrinsic neuron,antennal lobe glomerulus DM2,synapseNP1227,synapsekra-krasavietz,synapseSxl-NP2426,synapseSxl-NP2426, kra-krasavietz,synapseTab2-201Y,adult mushroom body,eye | pharate adult stage,head | pharate adult stage,synapseD42,adult thorax,dorsal denticle,cuprophilic cell,midgut constriction 2,interommatidial bristle" FBgn0004101 bs blistered http://flybase.org/reports/FBgn0004101 "FBgn0000156, FBgn0000223, FBgn0010354, FBgn0010535" protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR002100 core promoter proximal region sequence-specific DNA binding ; GO:0000987 | inferred from electronic annotation with InterPro:IPR033897 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with Mrtf activating transcription factor binding ; GO:0033613 | inferred from physical interaction with Mrtf" "terminal branching, open tracheal system ; GO:0007430 | traceable author statement terminal cell fate specification, open tracheal system ; GO:0035154 | traceable author statement short-term memory ; GO:0007614 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | traceable author statement pupal development ; GO:0035209 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement cell differentiation ; GO:0030154 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from expression pattern imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | non-traceable author statement wing disc development ; GO:0035220 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement open tracheal system development ; GO:0007424 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "bs/DSRF, DSRF, SRF, D-SRF, dSRF, BS, DmSRF, Group IIc, DSrf/bs, pruned/DSRF, dsrf, Srf, DSrf, px, ba, l(2)03267, Serf, CG3411, bs, bs/Dsrf, Bs, Mal, srf" "IPR002100:Transcription factor, MADS-box, IPR033897:MADS SRF-like" CG3411 11-Aug-17 DroID_v2017_08 "Drer\srfb, Drer\srfa" "Scer\MCM1, Scer\ARG80" "Cele\mef-2, Cele\unc-120" Xtro\srf Mmus\Srf Hsap\SRF " embryonic stage | >=stage 14 , embryonic stage | stage 16 , embryonic stage | stage >=14 " " abdominal segment 1--8

, embryonic/larval somatic muscle

, metathoracic segment | restricted

, embryonic central nervous system | restricted

, mesothoracic segment | restricted

, embryonic/larval midgut

, embryonic/larval hindgut

, pharyngeal muscle

" " embryonic stage | stage >=14 , embryonic stage | stage 16 , embryonic stage | >=stage 14 , pupal stage " " metathoracic segment | restricted

, mesothoracic segment | restricted

, embryonic/larval midgut

, embryonic/larval somatic muscle

, pharyngeal muscle

, abdominal segment 1--8

, embryonic/larval hindgut

, wing

, embryonic central nervous system | restricted

" "visible,recessive,viable,poor,fertile,semidominant,dominant,lethal,memory defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,somatic clone,wild-type,decreased cell size,cell autonomous,lethal - all die before end of pupal stage,some die during pupal stage,courtship behavior defective,locomotor behavior defective" "wing,wing vein,ectopic,trachea,wing cell,embryonic/larval tracheal system,somatic clone,tracheal metamere 3,wing vein L3 & sensillum campaniformium,sensillum campaniformium,wing & macrochaeta,macrochaeta,wing sensillum,tarsal segment,femur,rhabdomere,submarginal cell,wing disc,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,presumptive embryonic/larval tracheal system,cell non-autonomous,border follicle cell,follicle cell & actin filament | somatic clone,chaeta" FBgn0263977 Tim17b Translocase of the inner mitochondrial membrane 17b http://flybase.org/reports/FBgn0263977 protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000050380 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 protein targeting to mitochondrion ; GO:0006626 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 "Tim17b, CG40451" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG40451 11-Aug-17 DroID_v2017_08 "Drer\timm17a, Drer\timm17b" Scer\TIM17 "Cele\D2096.1, Cele\E04A4.5" Xtro\timm17a "Mmus\Timm17b, Mmus\Timm17a" "Hsap\TIMM17B, Hsap\TIMM17A" "increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage" mitochondrionunspecified FBgn0000233 btd buttonhead http://flybase.org/reports/FBgn0000233 - protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf4 inferred from physical interaction with Taf2 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay inferred from genetic interaction with HGNC:11205" posterior head segmentation ; GO:0035289 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype cephalic furrow formation ; GO:0007376 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype anterior head segmentation ; GO:0035288 | traceable author statement nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 "btd, BTD, CG12653, Btd, buttonhead" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG12653 11-Aug-17 DroID_v2017_08 "Drer\zgc:153115, Drer\sp3b, Drer\zgc:77358, Drer\sp9, Drer\sp3a, Drer\klf13, Drer\sp5l, Drer\sp2, Drer\sp4, Drer\sp1, Drer\klf11b, Drer\sp5b, Drer\sp7, Drer\sp8a, Drer\sp8b, Drer\sp5a" "Scer\FZF1, Scer\ACE2, Scer\MOT3, Scer\SWI5, Scer\CRZ1" "Cele\sptf-1, Cele\sptf-3, Cele\sptf-2" "Xtro\sp4, Xtro\sp5l, Xtro\sp2, Xtro\sp7, Xtro\sp5, Xtro\sp1, Xtro\sp6, Xtro\sp3" "Mmus\Sp6, Mmus\Sp9, Mmus\Sp5, Mmus\Sp4, Mmus\Sp7, Mmus\Egr1, Mmus\Egr4, Mmus\Klf13, Mmus\Sp1, Mmus\Sp8, Mmus\Egr3, Mmus\Zfp526, Mmus\Egr2, Mmus\Sp2" "Hsap\EGR1, Hsap\ZNF526, Hsap\SP7, Hsap\SP8, Hsap\EGR3, Hsap\SP9, Hsap\SP6, Hsap\SP4, Hsap\SP1, Hsap\SP5, Hsap\SP2, Hsap\SP3, Hsap\KLF13" " embryonic stage | embryonic cycle 12-14 , embryonic stage | blastoderm , embryonic stage | late , embryonic stage , embryonic stage | mid , embryonic stage | stage 3,4 , embryonic stage | stage 6,7 , embryonic stage | stage 5 , embryonic stage | stage 7-17 " " organism | 60-80% egg length

, embryonic intercalary segment | precursor

, ventral nerve cord | restricted

, embryonic deuterocerebrum | precursor

, embryonic mandibular segment | precursor

, organism | striped

, embryonic peripheral nervous system | restricted

, embryonic head | restricted

, cephalic furrow | anterior to

, leg | precursor

, organism | 70-80% egg length

, neuroblast

, procephalic neurogenic region | restricted

" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,homeotic,somatic clone,viable" "papilla organ,antennal segment,mandibular segment,antenna,cephalopharyngeal skeleton,ventral,embryo,embryonic abdominal segment,embryonic head & sclerite | ectopic,embryonic head,embryonic mandibular segment,embryonic intercalary segment,embryonic antennal segment,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,cephalic furrow,associated organ,dorsolateral papilla,embryonic/larval optic lobe,antennal sense organ,lateropharyngeal organ,maxillary segment,anterior,scolopidium,deuterocerebral neuromere,tritocerebral neuromere,intercalary segment,anterior pharyngeal organ,Keilin's organ,embryonic Malpighian tubule,femur,somatic clone - Minute background,tibia,eye,ectopic,wing,haltere,leg,somatic clone,wing margin bristle,distal,proximal" FBgn0005626 ple pale http://flybase.org/reports/FBgn0005626 "FBgn0003109, FBgn0003692" protein_coding_gene "tyrosine 3-monooxygenase activity ; GO:0004511 | inferred from electronic annotation with InterPro:IPR005962 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 tyrosine 3-monooxygenase activity ; GO:0004511 | non-traceable author statement tyrosine 3-monooxygenase activity ; GO:0004511 | traceable author statement" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR005962, InterPro:IPR018301, InterPro:IPR019773, InterPro:IPR019774 aromatic amino acid family metabolic process ; GO:0009072 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 dopamine biosynthetic process ; GO:0042416 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype catecholamine metabolic process ; GO:0006584 | non-traceable author statement developmental pigmentation ; GO:0048066 | traceable author statement cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype dopamine metabolic process ; GO:0042417 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from mutant phenotype inferred from genetic interaction with Ask1 thermotaxis ; GO:0043052 | inferred from mutant phenotype regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype thermosensory behavior ; GO:0040040 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype response to wounding ; GO:0009611 | inferred from expression pattern adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype" - "TH, DTH, Pale, CG10118, Th, VII, DH65B, pale, dTH65B, ple, pale/ple, th, dTH1, Ple" "IPR018301:Aromatic amino acid hydroxylase, iron/copper binding site, IPR001273:Aromatic amino acid hydroxylase, IPR005962:Tyrosine 3-monooxygenase, IPR019774:Aromatic amino acid hydroxylase, C-terminal, IPR019773:Tyrosine 3-monooxygenase-like" CG10118 11-Aug-17 DroID_v2017_08 "Drer\tph2, Drer\th2, Drer\tph1b, Drer\tph1a, Drer\pah, Drer\th" - "Cele\cat-2, Cele\tph-1, Cele\pah-1" "Xtro\tph1, Xtro\pah, Xtro\th" "Mmus\Th, Mmus\Tph1, Mmus\Tph2, Mmus\Pah" "Hsap\TH, Hsap\PAH, Hsap\TPH1, Hsap\TPH2" " adult stage , larval stage && adult stage , larval stage | third instar , larval stage , larval stage | first instar " " adult abdomen

, adult brain

, central nervous system

, adult head

, adult thorax

, epidermis

, larval central nervous system

" "visual behavior defective,phototaxis defective,locomotor rhythm defective,sleep defective,hypoactive,smell perception defective,gravitaxis defective,wild-type,lethal,recessive,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,somatic clone,body color defective,thermotaxis behavior defective,dominant,locomotor behavior defective,courtship behavior defective,feeding behavior defective,long lived,drug conditional,memory defective,viable" "wing,embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,adult cuticle,somatic clone,microchaeta,mouth hooks,cuticle,spiracle,macrochaeta,serotonergic neuron,wing cell,adult abdomen,adult thorax,dopaminergic neuron,drug conditional,mesothoracic tergum" DRSC11383 IEK 0.763470174 -1.621909565 -1.525471935 -2.188261945 -2.821184033 -3.427405512 FBgn0029157 ssh slingshot http://flybase.org/reports/FBgn0029157 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 actin binding ; GO:0003779 | inferred from biological aspect of ancestor with PANTHER:PTN000016922 phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | NOT inferred from direct assay protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement actin binding ; GO:0003779 | inferred from direct assay regulation of axonogenesis ; GO:0050770 | inferred from mutant phenotype negative regulation of actin filament polymerization ; GO:0030837 | inferred from direct assay protein dephosphorylation ; GO:0006470 | non-traceable author statement regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with sick protein dephosphorylation ; GO:0006470 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from genetic interaction with mbt regulation of actin polymerization or depolymerization ; GO:0008064 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype establishment of nucleus localization ; GO:0040023 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of lamellipodium assembly ; GO:0010591 | inferred from mutant phenotype cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR027232 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000016922 apical part of cell ; GO:0045177 | inferred from direct assay "Ssh, MKP, CG6238, Mkph, l(3)01207, ssh, SSH" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR014876:DEK, C-terminal, IPR016130:Protein-tyrosine phosphatase, active site, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR027232:Protein phosphatase Slingshot, IPR029021:Protein-tyrosine phosphatase-like" CG6238 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-175m17.7, Drer\dusp22a, Drer\styx, Drer\dusp2, Drer\dusp19b, Drer\LOC100150565, Drer\dusp13a, Drer\dusp6, Drer\ssh2a, Drer\dusp8b, Drer\dusp16, Drer\dupd1, Drer\dusp14, Drer\si:ch1073-184j22.2, Drer\dusp1, Drer\dusp22b, Drer\dusp7, Drer\dusp4, Drer\dusp3a, Drer\dusp8a, Drer\ssh1b, Drer\ssh2b, Drer\si:ch211-121a2.2, Drer\dusp5, Drer\dusp3b, Drer\dusp10, Drer\si:ch211-195b15.8, Drer\si:ch211-203d1.3, Drer\zgc:153044, Drer\dusp12, Drer\ssh1a, Drer\styxl1, Drer\dusp27, Drer\LOC100538052, Drer\si:ch211-223p8.8, Drer\dusp28, Drer\dusp19a, Drer\zgc:153981" "Scer\YVH1, Scer\MSG5, Scer\SDP1, Scer\PPS1" "Cele\vhp-1, Cele\Y54F10BM.13, Cele\lip-1, Cele\F13D11.3, Cele\C04F12.8, Cele\F26A3.4" "Xtro\dusp10, Xtro\dusp28, Xtro\dusp22, Xtro\dusp6, Xtro\epm2a, Xtro\dupd1, Xtro\dusp4, Xtro\ssh1, Xtro\dusp12, Xtro\styxl1, Xtro\styx, Xtro\dusp9, Xtro\dusp18, Xtro\ssh2, Xtro\dusp26, Xtro\dusp5, Xtro\dusp19, Xtro\dusp1, Xtro\dusp22a" "Mmus\Dusp18, Mmus\Ssh2, Mmus\Dusp10, Mmus\Dusp22, Mmus\Dusp9, Mmus\Dusp28, Mmus\Dupd1, Mmus\Dusp1, Mmus\Dusp12, Mmus\Dusp3, Mmus\Ssh1, Mmus\Dusp16, Mmus\Dusp26, Mmus\Dusp6, Mmus\Ssh3, Mmus\Dusp27, Mmus\Dusp4, Mmus\Dusp8, Mmus\Dusp14, Mmus\Dusp7, Mmus\Epm2a, Mmus\Dusp19, Mmus\Dusp21, Mmus\Dusp2, Mmus\Dusp5, Mmus\Dusp15, Mmus\Styx, Mmus\Styxl1, Mmus\Dusp13" "Hsap\DUSP26, Hsap\DUSP2, Hsap\DUPD1, Hsap\STYX, Hsap\DUSP22, Hsap\EPM2A, Hsap\DUSP7, Hsap\DUSP3, Hsap\DUSP8, Hsap\DUSP5, Hsap\DUSP15, Hsap\DUSP10, Hsap\DUSP9, Hsap\DUSP18, Hsap\DUSP6, Hsap\DUSP1, Hsap\STYXL1, Hsap\DUSP13, Hsap\DUSP4, Hsap\DUSP14, Hsap\DUSP21, Hsap\SSH3, Hsap\DUSP27, Hsap\SSH2, Hsap\DUSP16, Hsap\DUSP19, Hsap\SSH1, Hsap\DUSP12" "lethal,recessive,visible,somatic clone,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "denticle belt,embryonic/first instar larval cuticle,eye,somatic clone,maternal effect,ommatidium,rhabdomere,adult mushroom body & axon | somatic clone,medial branch of mushroom body,optic lobe neuron & axon | somatic clone,antennal lobe & axon | somatic clone,vertical lobe of adult mushroom body,filamentous actin & ommatidial cluster | ectopic | somatic clone,nucleus & ommatidial cluster | somatic clone,apical junction complex & ommatidial cluster | somatic clone,wing hair,macrochaeta & mesothoracic tergum | somatic clone,actin filament | cell autonomous | ectopic | somatic clone,filamentous actin | somatic clone,medial lobe of adult mushroom body" DRSC16730 K 0.360154131 0.621323091 -0.0240727 0.206665041 1.815135056 1.285103886 FBgn0001961 Arpc1 "Actin-related protein 2/3 complex, subunit 1" http://flybase.org/reports/FBgn0001961 - protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with HGNC:704 actin binding ; GO:0003779 | inferred from sequence or structural similarity actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000076207 cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype actin filament-based process ; GO:0030029 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from biological aspect of ancestor with PANTHER:PTN000076207 pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype axonal fasciculation ; GO:0007413 | inferred from genetic interaction with Arp3 compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity actin filament reorganization involved in cell cycle ; GO:0030037 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from genetic interaction with Arp3 negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from sequence or structural similarity with HGNC:704 detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with HGNC:704 Arp2/3 protein complex ; GO:0005885 | non-traceable author statement Arp2/3 protein complex ; GO:0005885 | traceable author statement "ArcP41, sop2, Arpc1, ARPC1, l(2)34Dd, ARPC1/p41, Spo2, Dsop2, CG8978, ARC-P41, sop2/arc41, l(2)Sop2, arc41, BG:DS00941.7, p42, 34Dd, br32, l(2)br32, DSop2, Sop2, D-sop2, Arc41, ArpC1, arpc1, sop, p41" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR017383:Actin-related protein 2/3 complex subunit 1" CG8978 11-Aug-17 DroID_v2017_08 "Drer\arpc1b, Drer\arpc1a, Drer\zgc:86896" Scer\ARC40 Cele\arx-3 "Xtro\arpc1a, Xtro\arpc1b" "Mmus\Arpc1b, Mmus\Arpc1a" "Hsap\ARPC1A, Hsap\ARPC1B" oogenesis stage | stage S9 ring canal

"lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,supernumerary,mesothoracic tergum,nurse cell,germline clone,follicle cell,somatic clone,epithelium,female germline cyst,filopodium,nurse cell ring canal,actin filament & nurse cell | germ-line clone,nucleus & nurse cell | germ-line clone,tormogen cell,macrochaeta,eye,ommatidium,lens,interommatidial bristle,macrochaeta & adult head | somatic clone,microchaeta & adult head | somatic clone,rhabdomere | adult stage | somatic clone,photoreceptor,retina,cell cycle | germline clone,metaphase & condensed nuclear chromosome | germ-line clone,centrosome | ectopic | germline clone,actin filament | germline clone,oocyte,nucleus | embryonic stage 4 | germline clone | non-rescuable maternal effect,actin filament | embryonic stage 4 | germline clone | non-rescuable maternal effect,nurse cell & actin filament | germ-line clone,anterior dorsocentral bristle,myoblast,mechanosensory chaeta,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,wing" FBgn0020510 Abi Abelson interacting protein http://flybase.org/reports/FBgn0020510 - protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:B1Q236,UniProtKB:P55162,UniProtKB:Q8MLQ0,UniProtKB:Q9VF87,UniProtKB:Q9VKM2 protein binding ; GO:0005515 | inferred from physical interaction with Abl protein binding ; GO:0005515 | inferred from physical interaction with Ptp61F protein binding ; GO:0005515 | inferred from physical interaction with ena protein binding ; GO:0005515 | inferred from physical interaction with Hem inferred from physical interaction with WASp" regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype axon extension involved in axon guidance ; GO:0048846 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from genetic interaction with Abl phagocytosis ; GO:0006909 | inferred from mutant phenotype positive regulation of protein kinase activity ; GO:0045860 | inferred from direct assay cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype positive regulation of cytoskeleton organization ; GO:0051495 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype lamellipodium assembly ; GO:0030032 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype central nervous system neuron axonogenesis ; GO:0021955 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype "SCAR complex ; GO:0031209 | inferred from direct assay lamellipodium membrane ; GO:0031258 | inferred from direct assay protein complex ; GO:0043234 | colocalizes_with inferred from physical interaction with WASp basal part of cell ; GO:0045178 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay SCAR complex ; GO:0031209 | colocalizes_with inferred from physical interaction with Hem, SCAR" "dAbi, Abi-1, CG9749, Ablphilin, Abi, abi" "IPR001452:SH3 domain, IPR012849:Abl-interactor, homeo-domain homologous domain, IPR028457:ABI family" CG9749 11-Aug-17 DroID_v2017_08 "Drer\abi3a, Drer\abi1b, Drer\abi2a, Drer\abi3b, Drer\abi2b, Drer\abi1a" - "Cele\abi-1, Cele\nck-1" "Xtro\abi2, Xtro\abi1" "Mmus\Abi3, Mmus\Abi2, Mmus\Abi1" "Hsap\ABI2, Hsap\ABI3, Hsap\ABI1" "neuroanatomy defective,recessive,lethal - all die before end of P-stage,some die during P-stage,visible,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,lethal,lethal - all die before end of embryonic stage,germline clone,some die during embryonic stage,cell shape defective,viable" "outer photoreceptor cell,tract,lamina,medulla,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,somatic clone,dorsocentral bristle,scutellar bristle,chaeta,sensory mother cell,longitudinal connective,maternal effect,filamentous actin | ectopicen-e16E,notopleural bristle,supernumerary,chaeta & mesothoracic tergum | ectopic-537.4,presumptive embryonic/larval nervous system" DRSC14099 K -0.025477939 -0.365066553 -0.494653164 -0.285618757 1.813661836 0.138283321 FBgn0020416 Idgf1 Imaginal disc growth factor 1 http://flybase.org/reports/FBgn0020416 FBgn0027915 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 imaginal disc growth factor receptor binding ; GO:0008084 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from direct assay wound healing ; GO:0042060 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular region ; GO:0005576 | non-traceable author statement "IDGF, IDGF1, IDGF-1, CG4472, idgf1, BG:DS02780.5, Idgf1, ldgf1, DmIDGF1" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG4472 11-Aug-17 DroID_v2017_08 "Drer\chia.5, Drer\ovgp1, Drer\chia.4, Drer\chia.6, Drer\si:ch211-226m16.2, Drer\chia.3, Drer\chia.2" Scer\CTS2 "Cele\cht-2, Cele\chil-23, Cele\chil-12, Cele\chil-4, Cele\chil-22, Cele\chil-13, Cele\T19H5.6, Cele\chil-25, Cele\chil-3, Cele\chil-2, Cele\chil-7, Cele\chil-15, Cele\lmd-5, Cele\chil-6, Cele\chil-5, Cele\chil-20, Cele\chil-18, Cele\chil-8, Cele\chil-16, Cele\chil-17, Cele\chil-24, Cele\chil-19, Cele\chil-11, Cele\lmd-4" "Xtro\ctbs, Xtro\chia, Xtro\LOC548945, Xtro\chit1" "Mmus\Chil1, Mmus\Chil6, Mmus\Ovgp1, Mmus\Chil3, Mmus\Chil5, Mmus\Chit1, Mmus\Chia1, Mmus\Chil4, Mmus\Ctbs" "Hsap\CHIT1, Hsap\CHIA, Hsap\OVGP1, Hsap\CHI3L1, Hsap\CHI3L2" " embryonic stage , larval stage | third instar , adult stage && oogenesis stage , embryonic stage && larval stage , embryonic stage&&larval stage " " yolk

, larval brain

, imaginal disc

, oocyte

, ventral furrow | vicinity of

, amnioproctodeal invagination | vicinity of

, nurse cell

, ring gland

, cephalic furrow | vicinity of

, larval optic lobe

, lymph gland

, embryonic/larval tracheal system

, embryonic/larval salivary gland

, embryonic/larval fat body

" viable DRSC03349 E -0.39789249 0.113950392 -1.664635496 0.59493807 -0.16923865 -0.150656505 FBgn0003888 betaTub60D beta-Tubulin at 60D http://flybase.org/reports/FBgn0003888 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002453, InterPro:IPR008280, InterPro:IPR017975 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity structural constituent of cytoskeleton ; GO:0005200 | inferred from direct assay" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002453, InterPro:IPR017975 response to light stimulus ; GO:0009416 | inferred from mutant phenotype heart development ; GO:0007507 | non-traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity larval behavior ; GO:0030537 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype" microtubule ; GO:0005874 | inferred from direct assay microtubule ; GO:0005874 | inferred from sequence or structural similarity "Tub60D, CG3401, betaTub60D, 143391_i_at, beta-tub, beta3 TU, beta-Tub6D, p50/tubulin, p53/tubulin, p50, p53, beta3, BETA 60D, D.m.BETA-60D, B3t, beta3-Tub, beta[[3]]-Tub, Dmbeta3, betaTub60C, T, beta3t, beta[[3]] tubulin, 3t, DTB3, beta[[3]]-tubulin, beta60C, betaTub3, beta-Tub60D, Tub, beta3Tub, betaTub, betatub60D, beta3-tubulin, beta3TUB, beta3tub, Tub2E, tubulin" "IPR000217:Tubulin, IPR002453:Beta tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain, IPR013838:Beta tubulin, autoregulation binding site" CG3401 11-Aug-17 DroID_v2017_08 "Drer\tubb6, Drer\tubb2b, Drer\zgc:153426, Drer\zgc:153264, Drer\zgc:65894, Drer\tubb2, Drer\tubb1, Drer\tubb5, Drer\zgc:55461, Drer\tubb4b" Scer\TUB2 "Cele\tbb-2, Cele\tbb-1, Cele\ben-1, Cele\tbb-4, Cele\mec-7" "Xtro\tubb4b, Xtro\tube1, Xtro\tubb2b, Xtro\tubb6, Xtro\tubb4a, Xtro\tubb3, Xtro\tubb" "Mmus\Tubb4a, Mmus\Tubb1, Mmus\Tubb3, Mmus\Tubb2a, Mmus\Tubb5, Mmus\Tubb2b, Mmus\Tubb4b, Mmus\Tubb6, Mmus\Tube1" "Hsap\TUBB6, Hsap\TUBB3, Hsap\TUBB8, Hsap\TUBB4B, Hsap\TUBB4A, Hsap\TUBB1, Hsap\TUBB2B, Hsap\TUBE1, Hsap\TUBB, Hsap\TUBB2A" " embryonic stage | stage 13 , embryonic stage | 0-10 hr , prepupal stage , larval stage | third instar , pupal stage | mid , oogenesis stage && adult stage | female , embryonic stage | stage 12 , embryonic stage | 9-15 hr , pupal stage , oogenesis stage && pupal stage , embryonic stage | stage 14 , embryonic stage | >=stage 11 , embryonic stage | stage 10 , adult stage | male , pupal stage | mid-late " " visceral mesoderm

, ventral metathoracic disc

, indirect flight muscle

, follicle cell

, mesoderm

, ovary

, head mesoderm

, dorsal metathoracic disc

, dorsal mesothoracic disc

, optic lobe | presumptive

, somatic mesoderm

, adult brain | presumptive

, testis | cyst cell

, muscle system

, eye-antennal disc

, testis

, ventral mesothoracic disc

, ventral prothoracic disc

" embryonic stage | stage 17 mesoderm | posterior | segmentally repeated pattern

"viable,sterile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,recessive,partially lethal - majority die,male fertile,fertile,flightless,phototaxis defective,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live,visible,male sterile,neuroanatomy defective,some die during pupal stage,locomotor behavior defective" "axoneme,meiotic cell cycle | male,embryonic/larval midgut,chordotonal organ & microtubulePx2),optic lobe,eye,lamina,medulla & axon,photoreceptor cell R8 & axon,photoreceptor cell R7 & axon,rhabdomere,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,tormogen cell,mesothoracic tergum" FBgn0001297 kay kayak http://flybase.org/reports/FBgn0001297 "FBgn0053956, FBgn0000468, FBgn0000725, FBgn0003506, FBgn0039693, FBtr0085478, FBpp0084844, FBtr0085479, FBpp0084845, FBtr0085480, FBpp0084846" protein_coding_gene "transcription factor binding ; GO:0008134 | traceable author statement DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with HDAC1 inferred from physical interaction with chm repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with vri transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Jra protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P18289 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Cka" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay JNK cascade ; GO:0007254 | non-traceable author statement adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | non-traceable author statement synaptic growth at neuromuscular junction ; GO:0051124 | inferred from genetic interaction with Jra wing disc development ; GO:0035220 | inferred from mutant phenotype second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | traceable author statement ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype embryo development ; GO:0009790 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement response to wounding ; GO:0009611 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | traceable author statement border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr dorsal closure ; GO:0007391 | non-traceable author statement collateral sprouting of injured axon ; GO:0048674 | inferred from mutant phenotype regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle ; GO:0031660 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with Jra "CG15509, CG15507, DFos, AP-1, Dfos, DFOS, D-fos, D-Fos, fos, Fos, AP1, d-fos, c-Fos, dFRA, dFos, Fra, DFra, dFra, dAP-1, kay, D-fos/kay, CG33956, Kay, dfos, c-fos, fbz, dlhD, fra, KAY, FOS, DM30, DM3" "IPR000837:AP-1 transcription factor, IPR004827:Basic-leucine zipper domain" CG33956 11-Aug-17 DroID_v2017_08 "Drer\atf1, Drer\fosab, Drer\batf, Drer\batf3, Drer\si:ch211-153j24.3, Drer\fosl1a, Drer\si:ch211-59d15.4, Drer\fosaa, Drer\atf7a, Drer\jdp2a, Drer\fosl1b, Drer\atf2, Drer\creb1a, Drer\fosl2, Drer\atf3, Drer\atf7b, Drer\creb5b, Drer\jdp2b, Drer\fosb, Drer\crema" "Scer\ACA1, Scer\CST6, Scer\SKO1" "Cele\fos-1, Cele\zip-11, Cele\crh-1" "Xtro\atf7, Xtro\atf3, Xtro\fosl2, Xtro\atf1, Xtro\batf, Xtro\creb5, Xtro\fos, Xtro\fosl1, Xtro\atf2, Xtro\fosb" "Mmus\Fos, Mmus\Atf1, Mmus\Atf7, Mmus\Atf3, Mmus\Batf3, Mmus\Fosl1, Mmus\Batf, Mmus\Creb5, Mmus\Atf2, Mmus\Batf2, Mmus\Jdp2, Mmus\Fosl2, Mmus\Fosb, Mmus\Creb1" "Hsap\ATF1, Hsap\FOS, Hsap\CREM, Hsap\BATF, Hsap\ATF2, Hsap\FOSL1, Hsap\JDP2, Hsap\CREB1, Hsap\ATF7, Hsap\FOSL2, Hsap\CREB5, Hsap\ATF3, Hsap\FOSB, Hsap\BATF3, Hsap\BATF2" " embryonic stage | stage 15 , embryonic stage , embryonic stage | 4-8 hr " " eo neuron

, dorsal ectoderm

, embryonic/larval midgut

, muscle attachment site

, amnioserosa

, embryonic/larval hindgut

, anal pad

, multidendritic neuron

, embryonic peripheral nervous system | restricted

, head | restricted

" "neuroanatomy defective,locomotor rhythm defective,viable,fertile,planar polarity defective,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,wild-type,lethal,wound healing defective,cell lethalcell lethal,heat sensitive,neurophysiology defective,conditional,partially,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,increased cell death,developmental rate defective,long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" "Kenyon cell,axoney-OK107,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,ommatidium,photoreceptor cell R4,somatic clone,embryonic/larval hemocyte | third instar larval stage,dendrite,RP2 motor neuron,eye photoreceptor cell,egg,maternal effect,dorsal appendage,nurse cell & nucleus | somatic clone,stage S14 oocyte,adult thorax,dorsal,mesothoracic cleft,embryonic dorsal epidermis,dorsal closure embryo,embryonic epidermis,embryonic head,embryo,wing disc,wing,embryonic ventral epidermis,follicle cell,stage S9 oocyte,embryonic/first instar larval cuticle,wing vein L3,wing vein L5,wing vein,heart primordium,scutellum,imaginal disc,pupal thorax,salivary gland,eye,cuprophilic cell,midgut interstitial cell,adult midgut precursor cell,bouton,neuromuscular junction | larval stage,terminal bouton,synapse,anterior crossvein,wing vein L2,wing vein L4,neuromuscular junctionBG380,segmental nerve,conditional,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,motor neuron,thorax,pigment cell,trichogen cell,mesothoracic tergum,adult heart,RU486 conditional,posterior" DRSC16977 IE 3.022447147 4.211683207 2.840500332 1.748045363 -0.463202103 -0.167621605 FBgn0038167 Lkb1 Lkb1 kinase http://flybase.org/reports/FBgn0038167 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein kinase activator activity ; GO:0030295 | inferred from biological aspect of ancestor with PANTHER:PTN001552748 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:11389 protein kinase activity ; GO:0004672 | non-traceable author statement" "peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:11389 positive regulation of protein serine/threonine kinase activity ; GO:0071902 | inferred from biological aspect of ancestor with PANTHER:PTN001552748 border follicle cell delamination ; GO:0030709 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype protein localization to cell cortex ; GO:0072697 | inferred from mutant phenotype inferred from genetic interaction with mira, fray maintenance of neuroblast polarity ; GO:0045201 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from direct assay establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement regulation of JNK cascade ; GO:0046328 | inferred from direct assay oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "lkb1, LKB1, Lkb1, dLKB1, DmLKB1, PAR-4, CG9374, LKB1/PEUTZ JEGHERS KINASE, STK11, par-4, anon-EST:Posey135, PAR4, dlkb1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG9374 11-Aug-17 DroID_v2017_08 Drer\stk11 "Scer\SAK1, Scer\TOS3" Cele\par-4 Xtro\stk11 Mmus\Stk11 Hsap\STK11 "hyperplasia,long lived,female limited,heat sensitive,cell polarity defective,mitotic cell cycle defective,decreased cell death,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,lethal,recessive,germline clone,maternal effect,cell cycle defective,cytokinesis defective" "wing,eye,embryonic/larval brain,ventral nerve cord,wing disc,wing blade,follicle cell,oocyte,germline clone,oocyte & microtubule | germ-line clone,border follicle cell,somatic clone,neuroblast,spindle,centrosome,brain,aster,kinetochore microtubule,spindle microtubule,spindleurd),asterurd),kinetochore microtubuleurd),spindle microtubuleurd),spindle & larval neuroblasturd),embryonic/larval neuroblast,centrosome & larval neuroblasturd),scutellum,adult thoracic sensillum" FBgn0015858 anon-14Ab anon-14Ab http://flybase.org/reports/FBgn0015858 - gene - - - "td28, anon-14Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011661 Moe Moesin http://flybase.org/reports/FBgn0011661 "FBgn0013950, FBgn0014345, FBgn0026689, FBgn0027218, FBgn0028282, FBgn0028289, FBgn0066841, FBgn0066842, FBgn0066843, FBgn0066844" protein_coding_gene "phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from direct assay actin binding ; GO:0003779 | non-traceable author statement actin binding ; GO:0003779 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Mer cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with conu microtubule binding ; GO:0008017 | inferred from mutant phenotype" "regulation of cell shape ; GO:0008360 | inferred from mutant phenotype positive regulation of mitotic spindle elongation ; GO:1902846 | inferred from mutant phenotype pole plasm protein localization ; GO:0007318 | traceable author statement establishment or maintenance of apical/basal cell polarity ; GO:0035088 | traceable author statement microtubule anchoring ; GO:0034453 | inferred from mutant phenotype positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | traceable author statement establishment or maintenance of polarity of larval imaginal disc epithelium ; GO:0016336 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype anterior/posterior pattern specification ; GO:0009952 | traceable author statement cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype actin filament-based process ; GO:0030029 | non-traceable author statement eye photoreceptor cell development ; GO:0042462 | traceable author statement determination of left/right symmetry ; GO:0007368 | inferred from mutant phenotype rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype cortical microtubule organization ; GO:0043622 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | traceable author statement oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | traceable author statement regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype protein localization ; GO:0008104 | traceable author statement rhabdomere development ; GO:0042052 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from direct assay positive regulation of cell proliferation ; GO:0008284 | inferred from genetic interaction with conu photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from direct assay actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype" "extrinsic component of membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798, InterPro:IPR011174, InterPro:IPR011259 cytosol ; GO:0005829 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay actin cytoskeleton ; GO:0015629 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement spindle ; GO:0005819 | colocalizes_with inferred from direct assay subapical complex ; GO:0035003 | traceable author statement actin filament ; GO:0005884 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | non-traceable author statement mitotic spindle midzone ; GO:1990023 | inferred from direct assay fusome ; GO:0045169 | NOT inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay" "Moe, moe, Dmoe, ERM, CG10701, EMR1, moesin/ezrin/radixin homolog mRNA, l(1)G0415, l(1)G0404, l(1)G0323, l(1)G0067, D17, Emr1, anon-WO03040301.161, anon-WO03040301.159, anon-WO03040301.157, anon-WO03040301.155, dMoe, Moes, gma, moesin, DMoe, Moesin" "IPR000299:FERM domain, IPR000798:Ezrin/radixin/moesin-like, IPR008954:Moesin tail domain, IPR011174:Ezrin/radixin/moesin, IPR011259:Ezrin/radixin/moesin, C-terminal, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR018979:FERM, N-terminal, IPR018980:FERM, C-terminal PH-like domain, IPR019747:FERM conserved site, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain" CG10701 11-Aug-17 DroID_v2017_08 "Drer\ezrb, Drer\nf2b, Drer\zgc:153953, Drer\nf2a, Drer\frmd4bb, Drer\ccdc120, Drer\si:ch211-163l21.4, Drer\msnb, Drer\ezra, Drer\si:ch211-220f12.1, Drer\si:ch211-169p10.1, Drer\msna" - "Cele\erm-1, Cele\nfm-1" "Xtro\ezr, Xtro\rdx, Xtro\msn, Xtro\nf2, Xtro\frmd4a, Xtro\frmd4b" "Mmus\Ezr, Mmus\Msn, Mmus\Ccdc120, Mmus\Nf2, Mmus\5730559C18Rik, Mmus\Rdx, Mmus\Frmd4b, Mmus\Frmd4a" "Hsap\EZR, Hsap\C1orf106, Hsap\NF2, Hsap\RDX, Hsap\FRMD4A, Hsap\FRMD4B, Hsap\CCDC120, Hsap\MSN" pupal stage mesothoracic bristle

"viable,smell perception defective,increased cell death,visible,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,somatic clone,song defective,lethal,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,developmental rate defective,recessive,size defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,male,female,fertile" "rhabdomere & actin filament, with MoedsRNA.327-775.UAS, hs.PB,rhabdomere & actin filament, with MoedsRNA.327-775.UAS, GMR.PF,photoreceptor cell,wing vein,wing,wing disc,wing hinge,rhabdomere & actin filament, with MoedsRNA.818-1326.UAS, hs.PB,rhabdomere & actin filament, with MoedsRNA.818-1326.UAS, GMR.PF,spindleC587,cyst progenitor cell,wing disc | third instar larval stage,1st posterior cell,wing blade,eye,somatic clone | third instar larval stage,germline cell,wing vein L3,rhabdomere & microvillushs.PB,rhabdomere & plasma membrane | apicalhs.PB,rhabdomere & cytoskeleton | apicalhs.PB,lamina plexus | third instar larval stage,medulla | third instar larval stage,oocyte & cytoskeleton[-],germline cell | embryonic stage,oocyte & cytoskeleton,imaginal disc,medulla,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R8,somatic clone,lamina plexus,embryonic abdominal segment,non-rescuable maternal effect,embryonic/first instar larval cuticle,pole cell,rhabdomere & plasma membrane | apical | somatic clone,rhabdomere & actin filament | somatic clone,basal lamina & dorsal mesothoracic disc & third instar larva,ommatidium,oocyte & actin filament,nurse cell & actin filament,embryonic/larval midgut primordium,embryonic hindgut,presumptive embryonic salivary gland,retina,dorsal trunk primordium,oocyte & actin filament | ectopicnos.UTR.THsimVP16,nurse cell & actin filamentnos.UTR.THsimVP16,nurse cell & actin filamentMoe-PG26,cell non-autonomous | third instar larval stage,cell autonomous | third instar larval stage" FBgn0013733 shot short stop http://flybase.org/reports/FBgn0013733 "FBgn0014183, FBgn0015972, FBgn0020296, FBgn0021837, FBgn0021937, FBgn0022152, FBgn0022170, FBgn0022208, FBgn0022230" protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR003108 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 microtubule binding ; GO:0008017 | traceable author statement actin binding ; GO:0003779 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with kra cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity actin binding ; GO:0003779 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z6P3 inferred from physical interaction with UniProtKB:Q8T3Y0 "negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | traceable author statement branch fusion, open tracheal system ; GO:0035147 | inferred from expression pattern muscle attachment ; GO:0016203 | traceable author statement axonogenesis ; GO:0007409 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | traceable author statement axonogenesis ; GO:0007409 | traceable author statement mushroom body development ; GO:0016319 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | traceable author statement branch fusion, open tracheal system ; GO:0035147 | traceable author statement sensory organ development ; GO:0007423 | traceable author statement oocyte fate determination ; GO:0030716 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype determination of muscle attachment site ; GO:0016204 | traceable author statement actin cytoskeleton organization ; GO:0030036 | traceable author statement axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | non-traceable author statement microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype inferred from genetic interaction with kra microtubule-based process ; GO:0007017 | inferred from direct assay microtubule bundle formation ; GO:0001578 | inferred from mutant phenotype regulation of axon extension ; GO:0030516 | inferred from mutant phenotype positive regulation of axon extension ; GO:0045773 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay adherens junction ; GO:0005912 | traceable author statement cytoskeleton ; GO:0005856 | non-traceable author statement muscle tendon junction ; GO:0005927 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay microtubule ; GO:0005874 | traceable author statement adherens junction ; GO:0005912 | inferred from direct assay microtubule plus-end ; GO:0035371 | inferred from direct assay astral microtubule ; GO:0000235 | inferred from direct assay axonal growth cone ; GO:0044295 | inferred from direct assay filopodium ; GO:0030175 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay "shot, kakp, kak, CG18076, shortstop/kakapo, Shot, grv, l(2)k04204, l(2)k03010, kop, Grv, 42/4, l(2)k10821, l(2)k05821, l(2)k05434, l(2)k15606, l(2)CA4, CG18637, Su(Mir)1" "IPR018159:Spectrin/alpha-actinin, IPR018247:EF-Hand 1, calcium-binding site, IPR001101:Plectin repeat, IPR001589:Actinin-type actin-binding domain, conserved site, IPR001715:Calponin homology domain, IPR002017:Spectrin repeat, IPR002048:EF-hand domain, IPR003108:Gas2-related domain, IPR011992:EF-hand domain pair, IPR001452:SH3 domain" CG18076 11-Aug-17 DroID_v2017_08 "Drer\eppk1, Drer\macf1a, Drer\si:ch211-137a8.2, Drer\syne1b, Drer\evplb, Drer\zgc:100997, Drer\dspa, Drer\syne2b, Drer\wu:fi04e12, Drer\gas2b, Drer\syne1a, Drer\dst, Drer\evpla, Drer\ppl, Drer\pleca, Drer\si:ch211-165e15.1" - Cele\vab-10 "Xtro\plec, Xtro\syne1, Xtro\macf1, Xtro\eppk1, Xtro\dst, Xtro\gas2l2, Xtro\syne2, Xtro\ppl, Xtro\evpl" "Mmus\Smtnl2, Mmus\Dst, Mmus\Clmn, Mmus\Ppl, Mmus\Syne2, Mmus\Macf1, Mmus\Plec, Mmus\Evpl, Mmus\Dsp, Mmus\Syne1, Mmus\Smtnl1" "Hsap\EPPK1, Hsap\PLEC, Hsap\EVPL, Hsap\MACF1, Hsap\SYNE1, Hsap\DSP, Hsap\EVPLL, Hsap\SYNE3, Hsap\PPL, Hsap\SYNE2, Hsap\DST, Hsap\GAS2L1, Hsap\GAS2L2, Hsap\CLMN, Hsap\KIAA0754" " embryonic stage , embryonic stage | stage >=13 , embryonic stage | stage >=11 , embryonic stage | stage 16 " " muscle attachment site

, embryonic peripheral nervous system

, epidermis

, embryonic central nervous system

, organism | segmentally repeated

" " embryonic stage | stage 16 , larval stage | third instar , embryonic stage , embryonic stage | stage >=14 , embryonic stage | stage 12-17 " " embryonic/larval proventriculus

, tendon cell

, scolopidium

, sensory neuron

, muscle attachment site

, epidermis

, chordotonal organ

, neuron

, embryonic/larval pharynx

, intersegmental nerve

" "lethal,recessive,neuroanatomy defective,paralytic,lethal - all die before end of embryonic stage,some die during embryonic stage,decreased cell number,somatic clone,germline clone,visible,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,chordotonal organ,lateral,scolopidial dendrite,extended germ band embryo,dorsal closure embryo,embryonic epidermis,dendrite & motor neuron | embryonic stage,axon & motor neuron | embryonic stage,neuron,microtubuleMK1),dendrite | dorsal | embryonic stage,presumptive embryonic/larval peripheral nervous system,dorsal,NMJ bouton,supernumerary,supernumerary | third instar larval stage,segmental nerve,RP3 motor neuron,embryonic/larval somatic muscle,embryonic/first instar larval cuticle,muscle attachment site,neuromuscular junction | embryonic stage,embryonic/larval mushroom body,somatic clone,lateral trunk primordium,intersegmental nerve,oocyte,egg chamber & follicle cell | somatic clone,mushroom body & axon,synapse & neuromuscular junction,chordotonal organ & axon | lateral,longitudinal connective,sensory neuron,ovary,germline clone,nurse cell,ectopic,microtubule & ovary | germ-line clone,centrosome & ovary | germ-line clone,axon & pCC neuron,abdominal segmental nerve,embryonic/larval dorsal anastomosis,dorsal trunk primordium,calyx of adult mushroom body,axonMK1),filopodiumMK1),wing,larva,proventriculus inner layer primordium,proventriculus intermediate layer primordium,embryonic proventriculus,embryonic/larval motor neuron,tendon cell,synapse & neuromuscular junctionMK1),RP1 motor neuron,tendon cell & actin filamenthow-24B, sr-md710,tendon cell & microtubulehow-24B, sr-md710" DRSC05459 IE -0.036086644 -3.390270537 -0.954132705 -4.143168369 -1.290758851 -1.384957247 FBgn0003093 Pkc98E Protein C kinase 98E http://flybase.org/reports/FBgn0003093 FBgn0005692 protein_coding_gene "protein kinase C activity ; GO:0004697 | inferred from electronic annotation with InterPro:IPR014376 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017892 protein kinase C activity ; GO:0004697 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000683254" peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype I-kappaB phosphorylation ; GO:0007252 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | non-traceable author statement dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with inaC "PKC-98F, PKC, PKC 98F, CG1954, 98F, dPKC98F, Dpkc3, PKC d98F, nPKC, Pkc3, Nc98F, Pkc98E, PKC98C, PKC98E, PK-C" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR014376:Protein kinase C, delta/epsilon/eta/theta types, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal, IPR020454:Diacylglycerol/phorbol-ester binding, IPR034669:Novel protein kinase C epsilon, catalytic domain, IPR000008:C2 domain" CG1954 11-Aug-17 DroID_v2017_08 "Drer\pkn1a, Drer\si:ch73-374l24.1, Drer\prkcq, Drer\zgc:153916, Drer\prkcda, Drer\pimr112, Drer\sgk494a, Drer\prkcea, Drer\prkcg, Drer\prkcbb, Drer\pkn3, Drer\si:ch211-14c7.2, Drer\sgk494b, Drer\pkn1b, Drer\prkchb, Drer\prkca, Drer\prkceb, Drer\prkcha, Drer\pkn2" "Scer\DUN1, Scer\PKC1" "Cele\cam-1, Cele\pkc-1, Cele\pkn-1, Cele\tpa-1, Cele\pkc-2" "Xtro\prkcq, Xtro\prkcb, Xtro\pkn3, Xtro\gpha2, Xtro\prkcd, Xtro\prkce, Xtro\prkca, Xtro\tnfrsf1a, Xtro\prkch, Xtro\LOC100493742, Xtro\prkcg, Xtro\pkn1" "Mmus\Prkcq, Mmus\Sprr1b, Mmus\Pkn1, Mmus\Gm5113, Mmus\Pkn2, Mmus\Prkch, Mmus\Prkcd, Mmus\Prkcg, Mmus\Prx, Mmus\Prkca, Mmus\Prkce, Mmus\Prkcb, Mmus\D130040H23Rik, Mmus\Sprr1a, Mmus\Pkn3, Mmus\BC030499" "Hsap\SGK494, Hsap\PRKCD, Hsap\PRKCB, Hsap\PKN3, Hsap\PRKCQ, Hsap\PRKCH, Hsap\PRX, Hsap\PKN1, Hsap\PKN2, Hsap\PRKCE, Hsap\PRKCG, Hsap\PRKCA" " larval stage | second instar , larval stage | third instar , embryonic stage , adult stage , larval stage | first instar , pupal stage " " cell body &&of adult brain

, head

" "chemical resistant,neuroanatomy defective,memory defective,viable" "denticle,ectopic,filzkorper,embryonic head,embryonic/first instar larval cuticle,embryonic/larval central nervous system" FBgn0003499 sr stripe http://flybase.org/reports/FBgn0003499 "FBgn0010828, FBgn0026215" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "ectoderm development ; GO:0007398 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype determination of muscle attachment site ; GO:0016204 | traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype inferred from genetic interaction with bnl pigment metabolic process ; GO:0042440 | traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype" - "Sr, l(3)06948, l(3)06948b, l(3)03999, CG7847, sr, SrB, stripe" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7847 11-Aug-17 DroID_v2017_08 "Drer\egr2b, Drer\egr4, Drer\osr1, Drer\egr2a, Drer\si:ch211-117k10.3, Drer\osr2, Drer\egr1, Drer\klf15, Drer\klf11a, Drer\sp2, Drer\egr3" "Scer\MIG1, Scer\MSN2, Scer\MIG3, Scer\MSN4, Scer\MIG2, Scer\FZF1" "Cele\odd-1, Cele\odd-2, Cele\egrh-3, Cele\egrh-1" "Xtro\sp2, Xtro\osr2, Xtro\klf15, Xtro\klf11, Xtro\osr1, Xtro\egr2, Xtro\egr3, Xtro\egr1" "Mmus\Sp2, Mmus\Osr1, Mmus\Klf11, Mmus\Egr4, Mmus\Egr1, Mmus\Osr2, Mmus\Egr2, Mmus\Egr3, Mmus\Klf15" "Hsap\SP2, Hsap\EGR4, Hsap\OSR1, Hsap\KLF11, Hsap\KLF15, Hsap\EGR1, Hsap\EGR3, Hsap\EGR2, Hsap\OSR2" " embryonic stage , embryonic stage | stage >=14 , embryonic stage && pupal stage " " muscle attachment site

, epidermis | restricted

" embryonic stage " epidermis | restricted

, muscle attachment site

" "lethal,recessive,viable,visible,flightless,lethal - all die before end of embryonic stage,some die during embryonic stage,cell shape defective,partially lethal - majority die,some die during pupal stage,eye color defective" "thorax,skeletal muscle of abdomen,adult muscle system,dorsal medial muscle,macrochaeta,somatic mesoderm,embryonic/larval dorsal branch,embryonic/larval dorsal trunk,embryonic/larval ganglionic branch,embryonic/larval muscle system,embryonic/larval visceral branch,lch5 cap attachment cell,lch5 ligament attachment cell,muscle fiber,muscle attachment site,embryonic/larval somatic muscle,embryonic/larval tracheal system,adult thorax,mesothoracic tergum & microchaetasr-md710,mesothoracic tergum & chaeta-C253,ventral,lateral transverse muscle | embryonic stage,abdominal 5 ventral longitudinal muscle | embryonic stage,abdominal 6 ventral longitudinal muscle | embryonic stage,abdominal 7 ventral longitudinal muscle | embryonic stage,abdominal 5 lateral transverse muscle | embryonic stage,abdominal 6 lateral transverse muscle | embryonic stage,abdominal 7 lateral transverse muscle | embryonic stage,embryonic somatic muscle,lateral,somatic muscle | embryonic stage,supernumerary,germ band,ectoderm,mesothoracic tergum" FBgn0029891 Pink1 PTEN-induced putative kinase 1 http://flybase.org/reports/FBgn0029891 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with rho-7 protein binding ; GO:0005515 | inferred from physical interaction with Pgam5 protein kinase activity ; GO:0004672 | inferred from direct assay "mitochondrial fission ; GO:0000266 | inferred from genetic interaction with Drp1 inferred from genetic interaction with Marf inferred from genetic interaction with Opa1 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype inferred from genetic interaction with Buffy mitochondrion transport along microtubule ; GO:0047497 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype negative regulation of programmed cell death ; GO:0043069 | inferred from mutant phenotype establishment of mitochondrion localization ; GO:0051654 | inferred from mutant phenotype negative regulation of mitochondrial fusion ; GO:0010637 | inferred from mutant phenotype regulation of mitochondrial electron transport, NADH to ubiquinone ; GO:1902956 | inferred from genetic interaction with FLYBASE:no biological data available-42; FB:FBgn0019957 positive regulation of compound eye pigmentation ; GO:0048078 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from direct assay sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype regulation of mitochondrion organization ; GO:0010821 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from mutant phenotype mitochondrial fission ; GO:0000266 | inferred from genetic interaction with Drp1 inferred from genetic interaction with Opa1 mitochondrion organization ; GO:0007005 | inferred from direct assay positive regulation of mitochondrial fission ; GO:0090141 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype intracellular distribution of mitochondria ; GO:0048312 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay Nebenkern ; GO:0016006 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "dPINK1, CG4523, BEST:GH23468, Pink1, PINK1, pink1, dPink1, PINK, dPINk1, Pink, :Pink1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG4523 11-Aug-17 DroID_v2017_08 Drer\pink1 - Cele\pink-1 - Mmus\Pink1 Hsap\PINK1 "visible,neuroanatomy defective,increased cell size,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile,progressive,sterile,chemical sensitive,osmotic stress response defective,male sterile,locomotor behavior defective,short lived,increased cell death,flightless,flight defective,heat stress response defective,smell perception defective,neurophysiology defective,recessive,gravitaxis defective,female sterile,partially" "eye,dopamine neuron & adult brainelav.PLu,ommatidium,dopamine neuron & adult brainDdc.PL,interommatidial bristle,pigment cell,photoreceptor & neuronGMR.PF,spermatid,Nebenkern,mitochondrial derivative,dopaminergic neuron,progressive,indirect flight muscle,mitochondrion,mitochondrial crista,mitochondrial crista & indirect flight muscle,minor mitochondrial derivative,wing,depressor muscle,myofibrilda.G32,mitochondrial cristada.G32,mitochondrionMhc.PW,myofibrilMhc.PW,mitochondrial cristaMhc.PW,mitochondrion & dorso-lateral dopaminergic neuronple.PF,adult thorax,mitochondrion & dopaminergic neuron,mitochondrion & indirect flight muscle,mitochondrial inner membrane & indirect flight muscle,mitochondrion & dorso-lateral dopaminergic neuron,dopaminergic PPL1 neuron,dopaminergic PPM1 neuron,dopaminergic PPM2 neuron,neuron,adult somatic muscle,mitochondrial outer membrane,adult antennal lobe,bouton,flight muscle,embryonic/larval neuromuscular junction,synaptic vesicle,spermatozoon,mitochondrial outer membrane & indirect flight muscle,myofibril & indirect flight muscle,dopamine neuron & adult brain,mitochondrion & dopamine neuron & adult brain,thorax,skeletal muscle of thorax,dorso-lateral dopaminergic neuron,Nebenkern derivative,spermatid cyst,eye | adult stage,ommatidium | adult stage" FBgn0039294 Cad96Cb Cadherin 96Cb http://flybase.org/reports/FBgn0039294 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 open tracheal system development ; GO:0007424 | inferred from genetic interaction with shg calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR020894 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "DCad96Cb, CG10421, CT29262, CG13664, Cad96Cb, cad96Cb, cad96C, cg13664, Cad96C" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site" CG13664 11-Aug-17 DroID_v2017_08 "Drer\pcdh2g8, Drer\LOC100006797, Drer\pcdh2g1, Drer\cdh6, Drer\pcdh1a6, Drer\cdhr1a" - Cele\cdh-9 "Xtro\pcdha13, Xtro\pcdh10, Xtro\pcdh9, Xtro\pcdh8, Xtro\cdh7, Xtro\cdh5" "Mmus\Pcdhb22, Mmus\Pcdh8, Mmus\Pcdhb14, Mmus\Pcdh7, Mmus\Pcdhb10, Mmus\Pcdhb17, Mmus\Cdh9, Mmus\Pcdh20, Mmus\Pcdhb9, Mmus\Pcdh19, Mmus\Pcdhb21, Mmus\Pcdhb5, Mmus\Pcdhb4, Mmus\Pcdhb11, Mmus\Pcdhb6, Mmus\Pcdhb3, Mmus\Pcdhb15, Mmus\Pcdhb1, Mmus\Pcdhb2, Mmus\Pcdhb7, Mmus\Gm37013, Mmus\Cdh6, Mmus\Pcdhgc5, Mmus\Pcdh9, Mmus\Cdhr1, Mmus\Pcdh10, Mmus\Pcdhb12, Mmus\Pcdhb8, Mmus\Pcdhb20, Mmus\Pcdhb13, Mmus\Pcdh12, Mmus\Pcdh17, Mmus\Pcdhb18, Mmus\Pcdhb19, Mmus\Pcdh18, Mmus\Pcdhb16" "Hsap\PCDH20, Hsap\PCDHGA4, Hsap\PCDH8, Hsap\PCDHA12, Hsap\PCDHGA1, Hsap\PCDHA3, Hsap\PCDHA11, Hsap\PCDHGC5, Hsap\PCDHA4, Hsap\PCDHB10, Hsap\PCDH18, Hsap\PCDHGA10, Hsap\PCDH15, Hsap\PCDHGA12, Hsap\PCDHAC2, Hsap\PCDHA10, Hsap\PCDHB15, Hsap\PCDHGA2, Hsap\PCDHA2, Hsap\PCDH10, Hsap\PCDH1, Hsap\PCDHA1, Hsap\PCDH19, Hsap\PCDHB11, Hsap\PCDHA5, Hsap\PCDHGB5, Hsap\PCDHB14, Hsap\PCDHGA11, Hsap\PCDH9, Hsap\PCDHA6, Hsap\CDH24, Hsap\CDH6, Hsap\PCDHB3, Hsap\PCDHA7, Hsap\PCDHB1, Hsap\PCDH17, Hsap\PCDHB12, Hsap\PCDHB4, Hsap\PCDHGB6, Hsap\PCDHB5, Hsap\PCDH7, Hsap\PCDHGC4, Hsap\PCDHB6, Hsap\PCDHB8, Hsap\PCDHGB4, Hsap\PCDHA8, Hsap\PCDHGB7, Hsap\PCDHB2, Hsap\PCDHB7, Hsap\PCDH12, Hsap\PCDHGA3, Hsap\PCDHB16, Hsap\PCDHA13, Hsap\PCDHAC1, Hsap\PCDHGA7, Hsap\PCDHGA6, Hsap\CDHR1, Hsap\PCDHGA9, Hsap\PCDHB13, Hsap\PCDHGA5, Hsap\PCDHA9, Hsap\PCDHGB1, Hsap\PCDHGA8, Hsap\PCDHGB2, Hsap\PCDHGC3, Hsap\PCDHB9, Hsap\PCDHGB3" "viable,partially lethal - majority die,some die during pupal stage" FBgn0026479 Drp1 Dynamin related protein 1 http://flybase.org/reports/FBgn0026479 "FBgn0005566, FBgn0005579, FBgn0031438, FBgn0042649" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000375, InterPro:IPR001401, InterPro:IPR003130, InterPro:IPR030381 microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000170013 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000170013" peroxisome fission ; GO:0016559 | inferred from electronic annotation with InterPro:IPR030556 synaptic vesicle budding from presynaptic endocytic zone membrane ; GO:0016185 | non-traceable author statement positive regulation of mitochondrial fission ; GO:0090141 | inferred from mutant phenotype ventral furrow formation ; GO:0007370 | inferred from mutant phenotype membrane fusion ; GO:0061025 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype mitochondrial fission ; GO:0000266 | inferred from mutant phenotype sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype mitochondrion localization ; GO:0051646 | inferred from mutant phenotype regulation of mitochondrial fission ; GO:0090140 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype dynamin family protein polymerization involved in mitochondrial fission ; GO:0003374 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay "CG3210, Dnm1/Drp1, l(2)22Fc, l(2)ND2, l(2)ND3, l(2)22Fd, Drp1, Drp-1, drp1, Drp, DRP1, drp-1, frat, DRP" "IPR030381:Dynamin-type guanine nucleotide-binding (G) domain, IPR000375:Dynamin central domain, IPR001401:Dynamin, GTPase domain, IPR003130:Dynamin GTPase effector, IPR019762:Dynamin, GTPase region, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020850:GTPase effector domain, IPR030556:Dynamin-1-like protein, IPR022812:Dynamin superfamily" CG3210 11-Aug-17 DroID_v2017_08 "Drer\mxd, Drer\dnm2a, Drer\si:dkeyp-110c12.3, Drer\mxa, Drer\mxc, Drer\mxe, Drer\dnm1b, Drer\dnm3a, Drer\mxg, Drer\dnm1a, Drer\mxf, Drer\dnm1l, Drer\si:dkey-32e23.4, Drer\mxb" "Scer\MGM1, Scer\VPS1, Scer\DNM1" "Cele\drp-1, Cele\dyn-1" "Xtro\dnm2, Xtro\dnm1, Xtro\dnm1l, Xtro\dnm3" "Mmus\Dnm2, Mmus\Dnm3, Mmus\Dnm1, Mmus\Mx1, Mmus\Dnm1l, Mmus\Mx2" "Hsap\DNM2, Hsap\MX1, Hsap\DNM3, Hsap\MX2, Hsap\DNM1, Hsap\DNM1L" "neurophysiology defective,lethal,recessive,viable,visible" "mitochondrion,Nebenkern,mitochondrionMef2.PR,mitochondrion & primary spermatocyte | germ-line clone,Nebenkern | germline clone,mitochondrial derivative | germline clone,lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous,ventral furrow,mitochondrion & larval salivary gland,mitochondrion & bouton,mitochondrion & larval nervous system,mitochondrion & motor neuron,embryonic/larval neuromuscular junction,trichogen cell" DRSC00574 K 1.078866981 -0.158466985 -0.040794711 -0.18690649 1.710953056 0.227550084 FBgn0033550 CG12341 - http://flybase.org/reports/FBgn0033550 protein_coding_gene - - - "BcDNA:SD17342, CG12341" IPR019334:Transmembrane protein 170 CG12341 11-Aug-17 DroID_v2017_08 "Drer\tmem170a, Drer\tmem170b" Scer\YPR153W Cele\F43G9.13 Xtro\tmem170a "Mmus\Tmem170, Mmus\Tmem170b" "Hsap\TMEM170A, Hsap\TMEM170B" viable FBgn0283521 lola longitudinals lacking http://flybase.org/reports/FBgn0283521 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein binding ; GO:0005515 | inferred from physical interaction with JIL-1 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with ttk" "regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 gonad development ; GO:0008406 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with SoxN positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:Q08605 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype inferred from genetic interaction with robo1 inferred from genetic interaction with sli larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 "lola, CG12052, eyeful, CG18381, CG18379, CG18378, CG30012, BTB-IV, LD03274, l(2)00642, l(2)s3697, bs06a08.y1, NEST:bs06a08, BcDNA:RH31485, sw59, CG30014, CG30013, CG18380, CG18376, BtbIV, BEST:LD03274, BcDNA:LD17006, Lola, fus7, btb" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type" CG12052 11-Aug-17 DroID_v2017_08 - "Scer\QDR3, Scer\CYK3" "Cele\sdz-28, Cele\btb-13" - Mmus\Zfp219 Hsap\ZBTB20 " embryonic stage | stage 12-17 , embryonic stage | stage >12 , embryonic stage | stage 1-15 , embryonic stage | stage >=10 , embryonic stage | stage 12-14 , embryonic stage | stage 10,11 , embryonic stage | stage 16-17 " " central nervous system

, histoblast

, organism

, mesoderm

, imaginal disc | presumptive

, embryonic peripheral nervous system

, mesectoderm

, embryonic optic lobe primordium

" " embryonic stage , larval stage | third instar , embryonic stage | stage 1-17 , embryonic stage | stage 1-13 , adult stage " " epithelial cell

, embryonic/larval somatic muscle

, central nervous system

, embryonic peripheral nervous system

, tracheocyte

, organism

, organism

" "neuroanatomy defective,courtship behavior defective,male,somatic clone,lethal,recessive,partially lethal - majority die,viable,fertile,behavior defective,visible,wild-type,partially,heat sensitive,some die during pupal stage,body color defective,size defective" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,dendrite & adult antennal lobe projection neuron | somatic cloneGH146,axon & adult antennal lobe projection neuron | somatic cloneGH146,adult antennal lobe projection neuron,somatic clone,adult antennal lobe projection neuron DA1 vPN,adult antennal lobe projection neuron VA1v vPN,adult antennal lobe projection neuron adPN,adult antennal lobe projection neuron lPN,adult antennal lobe projection neuron DL1 adPN,lateral horn,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lolae76,axon & adult antennal lobe projection neuron | somatic cloneGH146, lolae76,longitudinal connective,intersegmental nerve,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,abdominal segmental nerve,commissure,VUM interneuron 1,VUM interneuron 2,VUM interneuron 3,abdominal intersegmental nerve,abdominal 1 lateral monoscolopidial chordotonal organ lch1,abdominal 2 lateral monoscolopidial chordotonal organ lch1,abdominal 3 lateral monoscolopidial chordotonal organ lch1,abdominal 4 lateral monoscolopidial chordotonal organ lch1,abdominal 5 lateral monoscolopidial chordotonal organ lch1,abdominal 6 lateral monoscolopidial chordotonal organ lch1,abdominal 7 lateral monoscolopidial chordotonal organ lch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,VUM neuron,central nervous system,nurse cell,germline clone,egg chamber,axon & adult antennal lobe projection neuron | somatic clone,dendrite & adult antennal lobe projection neuron | somatic clone,macrochaeta,dorsocentral bristle,scutellar bristle,tormogen cell,gonad,gonadal sheath proper primordium,arista,eye,axon,antennal lobe projection neuron adPN,cell autonomous,antennal lobe projection neuron vPN,antennal lobe projection neuron lPN,dendrite & larval antennal lobe projection neuron | somatic clone | penetrance incomplete | expressivity incomplete | cell autonomous,axon & larval antennal lobe projection neuron | somatic clone | penetrance incomplete | expressivity incomplete | cell autonomous,adult mushroom body,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lola3.8.UAS,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lola4.7.UAS,axon & adult antennal lobe projection neuron | somatic cloneGH146, lola4.7.UAS,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lolaL.UAS,axon & adult antennal lobe projection neuron | somatic cloneGH146, lolaL.UAS,ventral longitudinal muscle,presumptive embryonic/larval central nervous system,dorsal appendage,synapsehow-24B,synapsetwi.PG,dendrite & adult antennal lobe projection neuron | somatic clone | heat sensitiveGH146,axon & adult antennal lobe projection neuron | somatic clone | heat sensitiveGH146,heat sensitive,embryonic/larval neuroblast,trichogen cell,mesothoracic tergum,ganglion mother cell,wing,posterior" DRSC27862 IEK 0.725057073 -1.799942145 5.589401193 -1.538656754 1.43490837 1.608543358 FBgn0085106 l(3)S068808 l(3)S068808 http://flybase.org/reports/FBgn0085106 gene - - - l(3)S068808 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061134 l(3)S001901 lethal (3) S001901 http://flybase.org/reports/FBgn0061134 gene - - - "0019/01, l(3)S001901" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0069234 gl(2L)159-23 gl(2L)159-23 http://flybase.org/reports/FBgn0069234 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)159-23 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive" FBgn0264651 loose-caboose loose caboose http://flybase.org/reports/FBgn0264651 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - loose-caboose - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval dorsal branch 10,embryonic/larval tracheal system,eye,somatic clone" FBgn0039379 CG5886 - http://flybase.org/reports/FBgn0039379 protein_coding_gene syntaxin binding ; GO:0019905 | inferred from electronic annotation with InterPro:IPR026183 - - CG5886 IPR026183:Taxilin family CG5886 11-Aug-17 DroID_v2017_08 "Drer\txlnba, Drer\slmapb, Drer\txlna, Drer\txlng, Drer\txlnbb" - Cele\T22C1.6 "Xtro\txlna, Xtro\txlng" "Mmus\Txlng, Mmus\Txlnb, Mmus\Txlna" "Hsap\TXLNB, Hsap\PPFIBP1, Hsap\TXLNA, Hsap\TXLNG" viable FBgn0023520 CG3857 - http://flybase.org/reports/FBgn0023520 - protein_coding_gene - "gravitaxis ; GO:0042332 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from sequence or structural similarity with UniProtKB:Q9H0W8" intracellular ; GO:0005622 | inferred from sequence or structural similarity with UniProtKB:Q9H0W8 "EG:39E1.3, CG3857" IPR027417:P-loop containing nucleoside triphosphate hydrolase CG3857 11-Aug-17 DroID_v2017_08 Drer\smg9 - Cele\smg-9 Xtro\smg9 Mmus\Smg9 Hsap\SMG9 "gravitaxis defective,viable,lethal" FBgn0051439 Muc96D Mucin 96D http://flybase.org/reports/FBgn0051439 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "CG31439, Muc96D" IPR002557:Chitin binding domain CG31439 11-Aug-17 DroID_v2017_08 - Scer\FLO5 - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0265758 CR44565 - http://flybase.org/reports/FBgn0265758 non_protein_coding_gene - - - "CR44565, lincRNA.590" - CR44565 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035954 Doc3 Dorsocross3 http://flybase.org/reports/FBgn0035954 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR002070, InterPro:IPR008967, InterPro:IPR018186" anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype cardiocyte differentiation ; GO:0035051 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Dm-DOC3, CG5093, Doc3, doc3, Doc" "IPR001699:Transcription factor, T-box, IPR002070:Transcription factor, Brachyury, IPR008967:p53-like transcription factor, DNA-binding, IPR018186:Transcription factor, T-box, conserved site" CG5093 11-Aug-17 DroID_v2017_08 "Drer\tbx6, Drer\tbx3b, Drer\tbx5b, Drer\tbx6l, Drer\tbx5a, Drer\tbx3a, Drer\tbx22, Drer\tbx20, Drer\tbx16, Drer\tbx18, Drer\tbr1b, Drer\mgaa, Drer\eomesa, Drer\tbx21, Drer\tbx2b, Drer\tbr1a, Drer\eomesb, Drer\ta, Drer\tbx4, Drer\tbx2a, Drer\tb, Drer\tbx19, Drer\tbx1" - "Cele\tbx-42, Cele\mls-1, Cele\tbx-11, Cele\tbx-2, Cele\mab-9, Cele\tbx-30" "Xtro\t2, Xtro\eomes, Xtro\tbx1, Xtro\tbx20, Xtro\tbx22, Xtro\tbx4, Xtro\tbx5, Xtro\mga, Xtro\t, Xtro\vegt, Xtro\tbx2, Xtro\tbr1, Xtro\tbx18, Xtro\tbx6, Xtro\tbx3" "Mmus\Tbx18, Mmus\Tbx2, Mmus\Tbx4, Mmus\Tbx22, Mmus\Eomes, Mmus\Tbx3, Mmus\Tbx19, Mmus\Tbr1, Mmus\Mga, Mmus\Tbx1, Mmus\Tbx6, Mmus\Tbx20, Mmus\Tbx15, Mmus\Tbx5, Mmus\T, Mmus\Tbx10, Mmus\Tbx21" "Hsap\TBX10, Hsap\TBX3, Hsap\EOMES, Hsap\MGA, Hsap\TBR1, Hsap\TBX21, Hsap\TBX22, Hsap\TBX4, Hsap\TBX20, Hsap\TBX18, Hsap\T, Hsap\TBX5, Hsap\TBX6, Hsap\TBX2, Hsap\TBX15, Hsap\TBX19, Hsap\TBX1" embryonic stage--pupal stage " embryonic stage , embryonic stage | stage 15-16 , embryonic stage | stage 5-15 , embryonic stage | stage 9-16 , embryonic stage | stage 5-11 " " mesoderm | restricted

, embryonic anterior Malpighian tubule

, abdominal lateral pentascolopidial chordotonal organ lch5

, amnioserosa

, parasegment && ectoderm && mesoderm

, cardioblast | subset

, dorsal pouch

, organism | dorso-lateral

, procephalic neurogenic region

" "viable,chemical resistant" FBgn0063373 snoRNA:snR38:54Ec snoRNA:snR38:54Ec http://flybase.org/reports/FBgn0063373 snoRNA_gene - - - "Snr38snoRNA, CR32901, snoRNA:snR38:54Ec" - CR32901 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060621 l(3)S088501b lethal (3) S088501b http://flybase.org/reports/FBgn0060621 gene - - - "0885/01, l(3)S088501b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038181 CG9297 - http://flybase.org/reports/FBgn0038181 protein_coding_gene - - - "CG9297, Dmel\CG9297" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022812:Dynamin superfamily, IPR031692:EH domain-containing protein, N-terminal" CG9297 11-Aug-17 DroID_v2017_08 "Drer\ehd1b, Drer\ehd3, Drer\srl, Drer\wu:fb80c09, Drer\ehd1a, Drer\chia.5, Drer\ehd2b, Drer\ovgp1, Drer\chia.1, Drer\ehd2a, Drer\ehd4" Scer\EDE1 "Cele\cht-1, Cele\cht-4, Cele\cht-2" "Xtro\ehd4, Xtro\chia, Xtro\ehd3, Xtro\srl, Xtro\ehd2, Xtro\ehd1, Xtro\chit1, Xtro\LOC548945" "Mmus\Ovgp1, Mmus\Chil6, Mmus\Ehd2, Mmus\Chil3, Mmus\Chil5, Mmus\Chia1, Mmus\Ehd3, Mmus\Ehd1, Mmus\Ehd4, Mmus\Srl, Mmus\Chil1, Mmus\Hmgn5, Mmus\Chit1" "Hsap\CHI3L2, Hsap\HMGN5, Hsap\CHIT1, Hsap\EHD1, Hsap\CHIA, Hsap\OVGP1, Hsap\EHD2, Hsap\EHD4, Hsap\CHI3L1, Hsap\SRL, Hsap\EHD3" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC16469 E 1.132200079 0.799375909 4.004378938 -1.050881108 -0.225437855 0.043052098 FBgn0052671 Rab9Fa Rab at 9Fa http://flybase.org/reports/FBgn0052671 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 "DmRabX3, CG2532, Rab9Fa, CG32671, RabX3" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG32671 11-Aug-17 DroID_v2017_08 "Drer\rab35a, Drer\si:dkey-16l2.16, Drer\rab19, Drer\zgc:171927, Drer\zgc:101559, Drer\rsg1, Drer\rabl6a, Drer\rab1aa, Drer\rab33ba, Drer\rab1ba, Drer\rab43, Drer\rab33a, Drer\rab1ab, Drer\rab35b, Drer\rab1bb, Drer\rabl6b" "Scer\TEM1, Scer\YPT1" "Cele\rab-28, Cele\rab-35" "Xtro\rabl6, Xtro\rab33a, Xtro\rab28, Xtro\rab19, Xtro\rab33b, Xtro\rab1a" "Mmus\Rab33b, Mmus\Rabl6, Mmus\Rab35, Mmus\Rab1b, Mmus\Rab43, Mmus\Rab1a, Mmus\Rsg1, Mmus\Rab28, Mmus\Rab19, Mmus\Rab33a" "Hsap\RAB33A, Hsap\RAB33B, Hsap\RAB28, Hsap\RAB19, Hsap\RAB1A, Hsap\RABL6, Hsap\RSG1, Hsap\RAB1B, Hsap\RAB43, Hsap\RAB35" FBgn0024545 l(3)L3130 lethal (3) L3130 http://flybase.org/reports/FBgn0024545 - gene - - - l(3)L3130 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061129 l(3)S003003a lethal (3) S003003a http://flybase.org/reports/FBgn0061129 gene - - - "l(3)S003003, 0030/03, l(3)S003003a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005371 whg whiting http://flybase.org/reports/FBgn0005371 - gene - - - whg - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective eye FBgn0060763 l(3)S063207 lethal (3) S063207 http://flybase.org/reports/FBgn0060763 gene - - - "0632/07, l(3)S063207" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264862 CR44053 - http://flybase.org/reports/FBgn0264862 non_protein_coding_gene - - - CR44053 - CR44053 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259933 CG42456 - http://flybase.org/reports/FBgn0259933 protein_coding_gene enzyme regulator activity ; GO:0030234 | inferred from electronic annotation with InterPro:IPR009914 dolichol metabolic process ; GO:0019348 | inferred from electronic annotation with InterPro:IPR009914 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from electronic annotation with InterPro:IPR009914 "CG42456, Dromel_CG12016_FBtr0073063_uORF" IPR009914:Dolichol phosphate-mannose biosynthesis regulatory CG42456 11-Aug-17 DroID_v2017_08 Drer\dpm2 Scer\YIL102C-A - - Mmus\Dpm2 Hsap\DPM2 FBgn0039282 Bili Band4.1 inhibitor LRP interactor http://flybase.org/reports/FBgn0039282 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of establishment of protein localization ; GO:0070201 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay "Bili, CG11848, dBili" "IPR000299:FERM domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR011993:PH domain-like" CG11848 11-Aug-17 DroID_v2017_08 "Drer\krit1, Drer\frmd8" - "Cele\kri-1, Cele\frm-10" Xtro\frmd8 "Mmus\Krit1, Mmus\Frmd8" "Hsap\KRIT1, Hsap\FRMD8" "viable,fertile" embryonic/first instar larval cuticle DRSC14405 IE 2.30752901 1.149307697 4.38860131 -0.530758612 1.121567693 0.456002575 FBgn0264001 bru3 bruno 3 http://flybase.org/reports/FBgn0264001 protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from direct assay negative regulation of translation ; GO:0017148 | inferred from sequence alignment with bru1 protein complex ; GO:0043234 | inferred from direct assay "CG43744, bruno-3, CG10046, CG12478, Dm Bru-3, cg12478, cg10046, Bru-3, l(3)05871, CG34243, bru-3, bru3" IPR000504:RNA recognition motif domain CG43744 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-205h23.2, Drer\celf3b, Drer\zgc:165603, Drer\celf5b, Drer\hug, Drer\celf2, Drer\celf1, Drer\celf5a, Drer\celf3a, Drer\celf4" - "Cele\unc-75, Cele\etr-1" "Xtro\celf1, Xtro\celf3, Xtro\celf4, Xtro\celf5, Xtro\celf2" "Mmus\Celf6, Mmus\Celf4, Mmus\Celf3, Mmus\Celf2, Mmus\Celf5, Mmus\Celf1" "Hsap\CELF3, Hsap\CELF6, Hsap\CELF2, Hsap\CELF4, Hsap\CELF1, Hsap\CELF5" DRSC22732 K -0.392388607 0.492353085 0.415812704 0.672242204 1.642179667 1.863616238 FBgn0259390 C403 - http://flybase.org/reports/FBgn0259390 gene - - - C403 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin,chaeta,ectopic" FBgn0050340 CG30340 - http://flybase.org/reports/FBgn0050340 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model" "BG:BACR48G21.1, BACR48G21.1, CG30340" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG30340 11-Aug-17 DroID_v2017_08 "Drer\mtnr1bb, Drer\mtnr1al, Drer\mtnr1c, Drer\mtnr1ab, Drer\mtnr1aa, Drer\mtnr1ba" - "Cele\npr-35, Cele\npr-5, Cele\npr-12, Cele\npr-8, Cele\npr-11" "Xtro\mtnr1c, Xtro\mtnr1b, Xtro\LOC100486065" "Mmus\Gpr50, Mmus\Mtnr1b, Mmus\Gpr3, Mmus\Mtnr1a" "Hsap\GPR3, Hsap\MTNR1B, Hsap\MTNR1A, Hsap\GPR50" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0038386 CG5478 - http://flybase.org/reports/FBgn0038386 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5478 - CG5478 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069990 BG01954 BG01954 http://flybase.org/reports/FBgn0069990 gene - - - BG01954 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0043979 Su(tor)293-12-3 Su(tor)293-12-3 http://flybase.org/reports/FBgn0043979 gene - - - "293-12-3, Su(tor)293-12-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053201 CG33201 - http://flybase.org/reports/FBgn0053201 protein_coding_gene - - - CG33201 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060308 l(3)S148214 lethal (3) S148214 http://flybase.org/reports/FBgn0060308 gene - - - "1482/14, l(3)S148214" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259258 EP-165 - http://flybase.org/reports/FBgn0259258 gene - - - EP-165 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing" FBgn0020652 HIF Hypoxia Inducible Factor http://flybase.org/reports/FBgn0020652 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "HIF-1, HIF-D, Hif-1, HIF" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051634 Oatp26F Organic anion transporting polypeptide 26F http://flybase.org/reports/FBgn0051634 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with Oatp58Db active transmembrane transporter activity ; GO:0022804 | inferred from sequence or structural similarity with Oatp58Db organic substance transport ; GO:0071702 | inferred from sequence or structural similarity with Oatp58Db integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Oatp58Db "CG31634, oatp 26F, CG18784, CG13767, CG11332, Oatp26F, oatp26F" "IPR004156:Organic anion transporter polypeptide OATP, IPR002350:Kazal domain, IPR020846:Major facilitator superfamily domain" CG31634 11-Aug-17 DroID_v2017_08 "Drer\slco1f2, Drer\LOC570448, Drer\slco1f3, Drer\slco1f4, Drer\slco4a1, Drer\LOC100536648, Drer\slco2b1, Drer\slco5a1, Drer\slco3a1, Drer\LOC101883455, Drer\slco1c1" - "Cele\K02G10.5, Cele\Y70G10A.3, Cele\F53B1.8" "Xtro\slco3a1, Xtro\slco5a1, Xtro\slco2a1, Xtro\slco1b3, Xtro\slco4a1, Xtro\slco4c1" "Mmus\Slco1b2, Mmus\Slco6d1, Mmus\Slco1a1, Mmus\Slco2b1, Mmus\Slco1a4, Mmus\Slco1c1, Mmus\Slco1a5, Mmus\Slco4c1, Mmus\Gm6614, Mmus\Slco4a1, Mmus\Slco1a6, Mmus\Gm5724, Mmus\Slco5a1, Mmus\Slco2a1, Mmus\Slco6c1, Mmus\Slco3a1" "Hsap\SLCO4A1, Hsap\SLCO1B7, Hsap\SLCO4C1, Hsap\SLCO6A1, Hsap\SLCO2A1, Hsap\SLCO1B3, Hsap\SLCO1A2, Hsap\SLCO5A1, Hsap\SLCO1B1, Hsap\SLCO1C1, Hsap\SLCO3A1, Hsap\SLCO2B1" viable FBgn0027254 l(1)G0249 lethal (1) G0249 http://flybase.org/reports/FBgn0027254 - gene - - - l(1)G0249 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265512 mlt mulet http://flybase.org/reports/FBgn0265512 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatid development ; GO:0007286 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype positive regulation of microtubule depolymerization ; GO:0031117 | inferred from mutant phenotype axoneme ; GO:0005930 | inferred from direct assay "CG12214, mlt, ms(2)4210, ms(2)ry3, ms(2)ry-3, ms(2)3, Tbcel, TBCE-like, TBCEL" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR029071:Ubiquitin-related domain, IPR000626:Ubiquitin domain" CG12214 11-Aug-17 DroID_v2017_08 "Drer\tbcelb, Drer\tbcela, Drer\tbce" Scer\PAC2 "Cele\coel-1, Cele\tbce-1" Xtro\tbcel "Mmus\Tbce, Mmus\Tbcel" "Hsap\TBCE, Hsap\TBCEL" DRSC27515 K 0.371158683 0.177647002 -0.25916353 -0.37351947 -0.13896648 1.745850798 FBgn0046329 l(2)38Ca lethal (2) 38Ca http://flybase.org/reports/FBgn0046329 gene - - - l(2)38Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027581 CG6191 - http://flybase.org/reports/FBgn0027581 - protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from electronic annotation with InterPro:IPR012388 phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype - "BcDNA:GH06193, CG6191, Dromel_CG6191_FBtr0087678_mORF" "IPR012388:CDK5 and ABL1 enzyme substrate 1/2, IPR015943:WD40/YVTN repeat-like-containing domain, IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like" CG6191 11-Aug-17 DroID_v2017_08 "Drer\cables2a, Drer\cables2b, Drer\cables1" - Cele\Y71F9B.6 "Xtro\cables1, Xtro\cables2" "Mmus\Cables2, Mmus\Cables1" "Hsap\CABLES1, Hsap\CABLES2" "viable,fertile,size defective" "wing,posterior" FBgn0035425 CG17746 - http://flybase.org/reports/FBgn0035425 protein_coding_gene cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR000222 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from electronic annotation with InterPro:IPR015655 phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with MGI:MGI:99878 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with MGI:MGI:99878 cytosol ; GO:0005829 | inferred from sequence or structural similarity with MGI:MGI:99878 "CG17746, PP2C, Cg17746" "IPR000222:PPM-type phosphatase, divalent cation binding, IPR001932:PPM-type phosphatase domain, IPR015655:Protein phosphatase 2C family" CG17746 11-Aug-17 DroID_v2017_08 "Drer\ppm1bb, Drer\ppm1nb, Drer\ppm1g, Drer\ppm1aa, Drer\ppm1ab, Drer\ppm1ba, Drer\ppm1na, Drer\ppm1f" "Scer\PTC1, Scer\PTC2, Scer\PTC3, Scer\PTC4" "Cele\fem-2, Cele\ppm-1, Cele\F42G9.1, Cele\ppm-2" "Xtro\ppm1b, Xtro\ppm1a" "Mmus\Ppm1g, Mmus\Tab1, Mmus\Ppm1f, Mmus\Ppm1n, Mmus\Ppm1b, Mmus\Ppm1e, Mmus\Ppm1a" "Hsap\PPM1E, Hsap\PPM1A, Hsap\PPM1F, Hsap\TAB1, Hsap\PPM1G, Hsap\PPM1N, Hsap\PPM1B" "viable,fertile,lethal" DRSC08521 E 0.012788365 1.009485774 0.993251345 1.900285157 -0.374090839 -0.240521204 FBgn0060825 l(3)S051303 lethal (3) S051303 http://flybase.org/reports/FBgn0060825 gene - - - "0513/03, l(3)S051303" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065302 l(2)SH1985 lethal (2) SH1985 http://flybase.org/reports/FBgn0065302 gene - - - "l(2)SH1985, l(2)SH2 1985" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002083 l(2)49Fl lethal (2) 49Fl http://flybase.org/reports/FBgn0002083 - gene - - - "vr-15, l(2)vr15, l(2)49Fl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,heat sensitive,non-suppressor of variegation,dominant" FBgn0016744 Su(Raf)3C Su(Raf)3C http://flybase.org/reports/FBgn0016744 - gene - - - Su(Raf)3C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026647 l(2)8bb lethal (2) 8bb http://flybase.org/reports/FBgn0026647 - gene - - - "8bb, l(2)8bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265737 CR44544 - http://flybase.org/reports/FBgn0265737 non_protein_coding_gene - - - "CR44544, incRNA.494, lincRNA.494" - CR44544 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011770 Gip GIP-like http://flybase.org/reports/FBgn0011770 - protein_coding_gene hydroxypyruvate isomerase activity ; GO:0008903 | inferred from sequence or structural similarity with UniProtKB:P30147 glyoxylate metabolic process ; GO:0046487 | inferred from sequence or structural similarity with UniProtKB:P30147 extracellular region ; GO:0005576 | inferred from direct assay "CG2227, T15, Gip, gene C" "IPR013022:Xylose isomerase-like, TIM barrel domain, IPR026040:Hydroxypyruvate isomerase-like" CG2227 11-Aug-17 DroID_v2017_08 Drer\hyi - Cele\C05D11.5 Xtro\hyi Mmus\Hyi Hsap\HYI viable FBgn0011909 tRNA:Leu-CAA-2-1 transfer RNA:Leucine-CAA 2-1 http://flybase.org/reports/FBgn0011909 "FBgn0003789, FBgn0052840, FBgn0052841, FBgn0060163" tRNA_gene UUG codon-amino acid adaptor activity ; GO:0033404 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033404 cytosol ; GO:0005829 | inferred by curator from GO:0033404 "CR32841, tRNA[Leu], DtL[a], leu-a, AE002787.trna17-LeuCAA, tRNA:L:CAA:AE002787-a, tRNA:leu3:49Fa, CR32840, tRNA[LEU], chr2R.trna76-LeuCAA, tRNA-Leu-CAA-2-1, tRNA:Leu-CAA-2-1, tRNA:L3:49Fa, UUG" - CR32841 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040239 bc10 bc10 http://flybase.org/reports/FBgn0040239 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "dbc10, CG4867, bc10" IPR009598:Bladder cancer-related BC10 CG4867 11-Aug-17 DroID_v2017_08 Drer\blcap - Cele\Y73E7A.6 Xtro\blcap Mmus\Blcap Hsap\BLCAP viable FBgn0002720 mesA messy A http://flybase.org/reports/FBgn0002720 - gene - - - "messy, mes-A, l(3)mes-1A, mesA" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,partially lethal - majority die,sterile" "head bristle,adult thorax & macrochaeta,anterior scutellar bristle,wing,posterior crossvein" FBgn0017422 anon-70Cb anon-70Cb http://flybase.org/reports/FBgn0017422 - gene - - - "t3, anon-70Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage && larval stage && pupal stage FBgn0025775 l(2)37Ad lethal (2) 37Ad http://flybase.org/reports/FBgn0025775 - gene - - - "l(2)02660, l(2)02660r, l(2)37Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033868 S-Lap7 Sperm-Leucylaminopeptidase 7 http://flybase.org/reports/FBgn0033868 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 extracellular space ; GO:0005615 | inferred from direct assay "CG13340, S-Lap7, S-LAP 7" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG13340 11-Aug-17 DroID_v2017_08 "Drer\zgc:152830, Drer\lap3, Drer\npepl1, Drer\rfwd2" - Cele\lap-1 "Xtro\lap3, Xtro\rfwd2" "Mmus\Rfwd2, Mmus\Npepl1, Mmus\Lap3" "Hsap\LAP3, Hsap\NPEPL1" FBgn0263268 del3 - http://flybase.org/reports/FBgn0263268 gene - gonad development ; GO:0008406 | inferred from mutant phenotype - del3 - - 11-Aug-17 DroID_v2017_08 - - - - - - gonad FBgn0267029 CR45473 - http://flybase.org/reports/FBgn0267029 non_protein_coding_gene - - - CR45473 - CR45473 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027508 Tnks tankyrase http://flybase.org/reports/FBgn0027508 FBgn0039351 protein_coding_gene scaffold protein binding ; GO:0097110 | inferred from physical interaction with Axn NAD+ ADP-ribosyltransferase activity ; GO:0003950 | inferred from direct assay positive regulation of telomere maintenance via telomerase ; GO:0032212 | inferred from electronic annotation with InterPro:IPR028731 Wnt signaling pathway ; GO:0016055 | inferred from electronic annotation with InterPro:IPR028731 spindle assembly ; GO:0051225 | inferred from electronic annotation with InterPro:IPR028731 protein ADP-ribosylation ; GO:0006471 | inferred from direct assay chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp inferred from genetic interaction with Chi regulation of proteasome assembly ; GO:0090364 | inferred from direct assay wing disc development ; GO:0035220 | inferred from genetic interaction with Bx - "BcDNA:LD22548, CG17487, CG4719, tankyrase, Dm.pARTb, Tnks, dTNKS, DTNKS, TNKS, Tankyrase, dARTD5, dTANK" "IPR001660:Sterile alpha motif domain, IPR002110:Ankyrin repeat, IPR012317:Poly(ADP-ribose) polymerase, catalytic domain, IPR013761:Sterile alpha motif/pointed domain, IPR020683:Ankyrin repeat-containing domain, IPR028731:Tankyrase-1, IPR015943:WD40/YVTN repeat-like-containing domain" CG4719 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-86e18.2, Drer\ankdd1a, Drer\tnksb, Drer\ank1b, Drer\pidd1, Drer\si:ch73-193i2.2, Drer\ank3a, Drer\psmd10, Drer\ankef1b, Drer\tnksa, Drer\si:ch73-252i11.1, Drer\trpn1, Drer\si:ch211-203b8.6, Drer\ankef1a, Drer\hace1, Drer\ankdd1b, Drer\ank3b, Drer\ank2a" Scer\NAS6 "Cele\F40G9.17, Cele\trp-4, Cele\K02B12.5" "Xtro\ank3, Xtro\LOC100492885, Xtro\tnks2, Xtro\ankdd1a, Xtro\tnks, Xtro\ankef1, Xtro\cat2, Xtro\parp14.3, Xtro\hace1, Xtro\ank1, Xtro\asb7, Xtro\ank2" "Mmus\Asb7, Mmus\Ankrd44, Mmus\Ankrd53, Mmus\Ank2, Mmus\Ank1, Mmus\Ankrd61, Mmus\Ankdd1b, Mmus\Ankef1, Mmus\Hace1, Mmus\Ankrd42, Mmus\Ankdd1a, Mmus\Pidd1, Mmus\Rnasel, Mmus\Ankrd60, Mmus\Tiparp, Mmus\Tnks, Mmus\Ankrd65, Mmus\Tnks2, Mmus\Ank3, Mmus\Psmd10" "Hsap\ANKDD1B, Hsap\ANK2, Hsap\ANKDD1A, Hsap\ANKRD61, Hsap\ANKRD60, Hsap\ASB7, Hsap\ANKRD65, Hsap\ANKRD53, Hsap\ANKEF1, Hsap\TNKS2, Hsap\ANK3, Hsap\PIDD1, Hsap\HACE1, Hsap\TNKS, Hsap\ANK1, Hsap\TIPARP, Hsap\PSMD10, Hsap\RNASEL" viable FBgn0260334 GSd414 - http://flybase.org/reports/FBgn0260334 gene - - - GSd414 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010587 l(2)04884 lethal (2) 04884 http://flybase.org/reports/FBgn0010587 - gene - - - l(2)04884 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0036186 CG6071 - http://flybase.org/reports/FBgn0036186 protein_coding_gene peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 extracellular space ; GO:0005615 | inferred from direct assay CG6071 "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG6071 11-Aug-17 DroID_v2017_08 "Drer\anpepa, Drer\erap1a, Drer\lnpep, Drer\erap2, Drer\enpep, Drer\erap1b, Drer\npepps, Drer\si:ch211-149p5.1, Drer\si:ch211-198g19.1, Drer\anpepb, Drer\si:ch211-276a23.5, Drer\si:ch211-106j24.1" "Scer\APE2, Scer\AAP1, Scer\TMA108" "Cele\R03G8.4, Cele\AC3.5, Cele\T12E12.6, Cele\Y67D8C.9, Cele\T07F10.1, Cele\T16G12.1, Cele\Y53F4B.20, Cele\VB0395L.1, Cele\mnp-1, Cele\F49B2.6, Cele\pam-1, Cele\R03G8.6, Cele\Y42A5A.1" "Xtro\lnpep, Xtro\lvrn, Xtro\anpep, Xtro\enpep, Xtro\npepps, Xtro\erap1" "Mmus\Anpep, Mmus\Npepps, Mmus\Lvrn, Mmus\Enpep, Mmus\Trhde, Mmus\Erap1, Mmus\Lnpep" "Hsap\ANPEP, Hsap\ERAP1, Hsap\ENPEP, Hsap\ERAP2, Hsap\TRHDE, Hsap\LNPEP, Hsap\NPEPPS, Hsap\LVRN" viable FBgn0000632 fap female abdomen pattern http://flybase.org/reports/FBgn0000632 - gene - - - fap - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female,recessive,body color defective" "abdominal tergite 6,abdominal tergite 7" FBgn0016702 Ras85D::Src64B Ras85D::Src64B http://flybase.org/reports/FBgn0016702 - engineered_fusion_gene - - - Ras85D::Src64B - - 11-Aug-17 DroID_v2017_08 - - - - - - "photoreceptor cell R7,eye" FBgn0000302 cha chaff http://flybase.org/reports/FBgn0000302 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available cha - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0085673 Su(Ste):CR41533 - http://flybase.org/reports/FBgn0085673 non_protein_coding_gene - - - "CG41533, CR41533, Su(Ste):CR41533, Su(Ste)" - CR41533 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019623 Crlbp Chemical-sense-related lipophilic-ligand-binding protein http://flybase.org/reports/FBgn0019623 - gene - - - Crlbp - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069229 gl(2L)343-11 gl(2L)343-11 http://flybase.org/reports/FBgn0069229 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(2L)343-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect" FBgn0004938 ABO-YL Abnormal Oocyte on YL http://flybase.org/reports/FBgn0004938 - region - - - "ABO, ABO-YL" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004023 wrl whirligig http://flybase.org/reports/FBgn0004023 - gene - microtubule-based process ; GO:0007017 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype - "nc4, ms(3)nc4, EcRms4, wrl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,dominant,recessive,viable" spermatid axoneme FBgn0030621 CG15030 - http://flybase.org/reports/FBgn0030621 protein_coding_gene - - - CG15030 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19611 I 1.682582919 -1.125804612 -0.837113938 0.438017978 0.149972023 0.519726808 FBgn0022812 E(faf)E306 Enhancer of faf E306 http://flybase.org/reports/FBgn0022812 - gene - - - E(faf)E306 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030687 CG17209 - http://flybase.org/reports/FBgn0030687 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000453624" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083" DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000453624 CG17209 "IPR000722:RNA polymerase, alpha subunit, IPR006592:RNA polymerase, N-terminal, IPR007066:RNA polymerase Rpb1, domain 3, IPR007080:RNA polymerase Rpb1, domain 1, IPR007081:RNA polymerase Rpb1, domain 5, IPR007083:RNA polymerase Rpb1, domain 4" CG17209 11-Aug-17 DroID_v2017_08 "Drer\polr2a, Drer\ubxn7, Drer\polr3a" "Scer\RPO21, Scer\RPO31" Cele\rpc-1 "Xtro\polr3a, Xtro\ubxn7" "Mmus\Polr2a, Mmus\Ubxn7, Mmus\Polr3a" "Hsap\UBXN7, Hsap\POLR3A, Hsap\POLR2A" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC19766 K -0.301337531 0.160980242 -0.963043534 0.482878275 2.135652684 -0.893814352 FBgn0034076 Jhedup Juvenile hormone esterase duplication http://flybase.org/reports/FBgn0034076 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 - - "CG8424, Jhedup, JHEdup, JHE" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG8424 11-Aug-17 DroID_v2017_08 "Drer\cell, Drer\si:ch211-93f2.1, Drer\nlgn4b, Drer\nlgn4a, Drer\nlgn2b, Drer\cel.1, Drer\nlgn3b, Drer\nlgn1, Drer\ces3, Drer\ces2, Drer\nlgn2a, Drer\nlgn3a" - "Cele\K11G9.3, Cele\T28C12.5, Cele\F07C4.12, Cele\C23H4.2, Cele\C23H4.3, Cele\K11G9.2, Cele\C17H12.4, Cele\E01G6.3, Cele\Y71H2AM.13, Cele\C23H4.4, Cele\F15A8.6, Cele\T02B5.1, Cele\K07C11.4, Cele\ZK994.1, Cele\T28C12.4, Cele\C23H4.7, Cele\C52A10.2, Cele\T02B5.3, Cele\F56C11.6, Cele\F13H6.3, Cele\ZC376.3, Cele\B0238.1, Cele\ZC376.2, Cele\ZC376.1, Cele\T22D1.11, Cele\K11G9.1, Cele\C42D4.2, Cele\C52A10.1, Cele\R173.3, Cele\C01B10.4, Cele\C01B10.10" "Xtro\ces2, Xtro\cel, Xtro\nlgn2, Xtro\nlgn3, Xtro\nlgn4x, Xtro\ces3, Xtro\LOC100494782" "Mmus\Ces2c, Mmus\Ces2f, Mmus\Ces1b, Mmus\Ces2e, Mmus\Ces5a, Mmus\Nlgn3, Mmus\Ces2a, Mmus\Ces2h, Mmus\Ces1c, Mmus\Nlgn2, Mmus\Ces2b, Mmus\Ces3a, Mmus\Ces1e, Mmus\Ces3b, Mmus\Ces4a, Mmus\Cel, Mmus\Ces2g, Mmus\Ces1d, Mmus\Ces1h, Mmus\Nlgn1, Mmus\Ces1f, Mmus\Ces1g" "Hsap\CES4A, Hsap\CEL, Hsap\CES3, Hsap\CES1, Hsap\NLGN4Y, Hsap\NLGN3, Hsap\NLGN2, Hsap\CES2, Hsap\CES5A, Hsap\NLGN1, Hsap\NLGN4X" viable FBgn0053143 CG33143 - http://flybase.org/reports/FBgn0053143 protein_coding_gene - - - "CG4232, CG13509, CG33143, 33143, mdcds_16487" "IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold, IPR032073:Fibronectin type III domain-containing protein 5, C-terminal domain" CG33143 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065091 snmRNA:463 small non-messenger RNA 463 http://flybase.org/reports/FBgn0065091 non_protein_coding_gene - - - "Dm-463, snmRNA:463" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085547 CG40971 - http://flybase.org/reports/FBgn0085547 protein_coding_gene - - - CG40971 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029033 l(2)Q73 lethal (2) Q73 http://flybase.org/reports/FBgn0029033 gene - - - "Q73, l(2)Q73" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003106 PL(3)sp-W1 Polygenic locus sternopleural W1 http://flybase.org/reports/FBgn0003106 - gene - - - "a, PL(3)sp[W1], PL(3)sp-W1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034684 CG13501 - http://flybase.org/reports/FBgn0034684 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13501 "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG13501 11-Aug-17 DroID_v2017_08 Drer\rsph14 - - Xtro\rsph14 Mmus\Rsph14 Hsap\RSPH14 viable FBgn0038683 CG11779 - http://flybase.org/reports/FBgn0038683 protein_coding_gene chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000076497 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O43615 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000076497 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O43615 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:O43615 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000076497 "BcDNA:GM03811, BEST:GM03811, CG11779, CG117799, GH-18370" "IPR007379:Tim44-like domain, IPR017303:Mitochondrial import inner membrane translocase subunit Tim44, IPR032710:NTF2-like domain" CG11779 11-Aug-17 DroID_v2017_08 Drer\timm44 Scer\TIM44 Cele\tin-44 Xtro\timm44 Mmus\Timm44 Hsap\TIMM44 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "eye,trichogen cell,mesothoracic tergum" FBgn0028120 l(3)S060313 lethal (3) S060313 http://flybase.org/reports/FBgn0028120 gene - - - "l(3)S060313, l(3)s001813" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025840 E(var)915 E(var)915 http://flybase.org/reports/FBgn0025840 - gene - - - "E-915, E(var)915" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0284442 Mcm3 Minichromosome maintenance 3 http://flybase.org/reports/FBgn0284442 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008046, InterPro:IPR018525 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008046, InterPro:IPR018525 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR008046 mushroom body development ; GO:0016319 | inferred from mutant phenotype neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008046 MCM complex ; GO:0042555 | inferred from electronic annotation with InterPro:IPR008046 "mcm3, smu, Mcm3, CG4206, MCM3, DmMcm3, DmMCM3, dMCM3, PCR2, Mcp-PCR2, McM3, DmeMCM3, dMcm3" "IPR033762:MCM OB domain, IPR031327:Mini-chromosome maintenance protein, IPR018525:Mini-chromosome maintenance, conserved site, IPR001208:MCM domain, IPR003593:AAA+ ATPase domain, IPR008046:DNA replication licensing factor Mcm3, IPR012340:Nucleic acid-binding, OB-fold, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027925:MCM N-terminal domain" CG4206 11-Aug-17 DroID_v2017_08 "Drer\mcm3, Drer\mcm3l" Scer\MCM3 Cele\mcm-3 Xtro\mcm3 Mmus\Mcm3 Hsap\MCM3 " adult stage | female , egg stage | unfertilized egg , embryonic stage | 0-4 hr , embryonic stage | stage 11-12 " " unfertilized egg

, embryonic central nervous system

" "radiation sensitive,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0026077 Gasp Gasp http://flybase.org/reports/FBgn0026077 FBgn0026290 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis "chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay "gasp, gammaBert27, anon-EST:ParkEST180, CG10287, Gasp, obst-C, 2A12" IPR002557:Chitin binding domain CG10287 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\dct-9, Cele\cbd-1, Cele\cpg-2" - - - viable FBgn0001983 wor worniu http://flybase.org/reports/FBgn0001983 - protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with esg inferred from sequence or structural similarity with sna" "dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity brain development ; GO:0007420 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with esg, sna" nucleus ; GO:0005634 | inferred from sequence or structural similarity "Wor, l(2)35Da, BG:DS03023.1, l(2)br35, l35Da, br35, CG4158, wor" IPR013087:Zinc finger C2H2-type CG4158 11-Aug-17 DroID_v2017_08 "Drer\scrt1b, Drer\snai1b, Drer\scrt2, Drer\si:dkeyp-113d7.10, Drer\snai3, Drer\snai2, Drer\snai1a, Drer\scrt1a" "Scer\RPH1, Scer\AZF1" Cele\snai-1 "Xtro\wt1, Xtro\snai1, Xtro\snai2" "Mmus\Scrt2, Mmus\Scrt1, Mmus\Snai3, Mmus\Zfp128, Mmus\Snai1, Mmus\Snai2" "Hsap\ZNF8, Hsap\SNAI3, Hsap\SNAI2, Hsap\SNAI1, Hsap\ZNF461, Hsap\SCRT1, Hsap\SCRT2" " embryonic stage | stage >=8 , embryonic stage | stage >=13 , embryonic stage | stage >=9 " " procephalic neurogenic region

, embryonic brain

, ventral nerve cord

, neuroblast

" "neuroanatomy defective,partially lethal - majority die,lethal,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,visible" "ventral nerve cord,denticle belt,embryonic/larval brain,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,chaeta,supernumerary" FBgn0010137 l(2)62B10 lethal (2) of Spiess 62B10 http://flybase.org/reports/FBgn0010137 - gene - - - l(2)62B10 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036575 CG5157 - http://flybase.org/reports/FBgn0036575 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 - - CG5157 "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR018506:Cytochrome b5, heme-binding site" CG5157 11-Aug-17 DroID_v2017_08 "Drer\fads2, Drer\cyb5b, Drer\cyb5a" "Scer\CYB2, Scer\CYB5, Scer\SCS7, Scer\OLE1" "Cele\cytb-5.1, Cele\cytb-5.2" "Xtro\cyb5b, Xtro\cyb5a" "Mmus\Cyb5a, Mmus\Cyb5d1, Mmus\Fads1, Mmus\Cyb5b" "Hsap\FADS2, Hsap\CYB5B, Hsap\CYB5A" viable FBgn0058154 CG40154 - http://flybase.org/reports/FBgn0058154 protein_coding_gene - - - CG40154 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034502 CG13871 - http://flybase.org/reports/FBgn0034502 protein_coding_gene - - - CG13871 - CG13871 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038647 CG14302 - http://flybase.org/reports/FBgn0038647 protein_coding_gene - - - "BcDNA:LP02994, CG14302" - CG14302 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263378 CR43430 - http://flybase.org/reports/FBgn0263378 non_protein_coding_gene - - - CR43430 - CR43430 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022158 l(2)k05722 lethal (2) k05722 http://flybase.org/reports/FBgn0022158 - gene - - - l(2)k05722 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267443 CR45793 - http://flybase.org/reports/FBgn0267443 non_protein_coding_gene - - - "CR45793, Mgn095159" - CR45793 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067870 Mod(Prat:bw)3-5 Mod(Prat:bw)3-5 http://flybase.org/reports/FBgn0067870 gene - - - "Mod-3-5, Mod(Prat:bw)3-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - enhancer of variegation FBgn0032387 CG16965 - http://flybase.org/reports/FBgn0032387 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR005195, InterPro:IPR008928, InterPro:IPR012341" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR005195 - CG16965 "IPR005195:Glycoside hydrolase, family 65, central catalytic, IPR008928:Six-hairpin glycosidase-like" CG16965 11-Aug-17 DroID_v2017_08 Drer\pgghg Scer\ATH1 - Xtro\athl1 Mmus\Pgghg Hsap\PGGHG viable FBgn0043557 Su(ro[DOM])2014 Su(ro[DOM])2014 http://flybase.org/reports/FBgn0043557 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])2014 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062643 EP707 EP707 http://flybase.org/reports/FBgn0062643 gene - - - "EP(3)0707, EP707" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082330 HM813 HM813 http://flybase.org/reports/FBgn0082330 gene - - - HM813 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002388 l(3)93Dd lethal (3) 93Dd http://flybase.org/reports/FBgn0002388 - gene - - - "er9, l(3)er9, l(3)93Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal" eye FBgn0002429 l(3)F55 lethal (3) F55 http://flybase.org/reports/FBgn0002429 - gene - - - "l(3)55, l(3)F55" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" wing FBgn0263382 CR43434 - http://flybase.org/reports/FBgn0263382 non_protein_coding_gene - - - CR43434 - CR43434 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261523 CG42658 - http://flybase.org/reports/FBgn0261523 protein_coding_gene - - endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR016763 CG42658 "IPR016763:Vesicle-associated membrane-protein-associated protein, IPR013783:Immunoglobulin-like fold, IPR008962:PapD-like, IPR000535:Major sperm protein (MSP) domain" CG42658 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069304 X-86-9 X-86-9 http://flybase.org/reports/FBgn0069304 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-86-9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect,filzkorper" FBgn0022970 snRNPA snRNPA http://flybase.org/reports/FBgn0022970 - gene - - nucleus ; GO:0005634 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from direct assay "A, snRNPA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015488 l(2)46Cl lethal (2) 46Cl http://flybase.org/reports/FBgn0015488 - gene - - - "T, l(2)46Cl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0086913 Rab26 Rab26 http://flybase.org/reports/FBgn0086913 protein_coding_gene GTP binding ; GO:0005525 | inferred from sequence or structural similarity with UniProtKB:P51156 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 vesicle docking involved in exocytosis ; GO:0006904 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 protein localization to plasma membrane ; GO:0072659 | inferred from biological aspect of ancestor with PANTHER:PTN000635134 protein secretion ; GO:0009306 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 regulation of exocytosis ; GO:0017157 | inferred from sequence or structural similarity with UniProtKB:P51156 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 intrinsic component of plasma membrane ; GO:0031226 | inferred from sequence or structural similarity with UniProtKB:P51156 recycling endosome ; GO:0055037 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from biological aspect of ancestor with PANTHER:PTN001530779 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000635134 synapse ; GO:0045202 | inferred from direct assay "rab26, AAF51708, DmRab26, CG7605, Rab26, CG32439, CG34410, Q8IPT6, Q9VP48" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain" CG34410 11-Aug-17 DroID_v2017_08 Drer\zgc:112183 Scer\SEC4 Cele\rab-37 "Xtro\rab26, Xtro\rab37" "Mmus\Rab37, Mmus\Rab26" "Hsap\RAB37, Hsap\RAB26" viable FBgn0082355 HM298 HM298 http://flybase.org/reports/FBgn0082355 gene - - - HM298 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020881 als alae sublatae http://flybase.org/reports/FBgn0020881 - gene - - - "als, Mps1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016809 l(1)L10 lethal (1) L10 http://flybase.org/reports/FBgn0016809 - gene - - - "l(1)L10, L10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051238 CG31238 - http://flybase.org/reports/FBgn0051238 protein_coding_gene - - - CG31238 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000564 Eh Eclosion hormone http://flybase.org/reports/FBgn0000564 FBgn0026855 protein_coding_gene ecdysis-triggering hormone activity ; GO:0008255 | inferred from electronic annotation with InterPro:IPR006825 neuropeptide hormone activity ; GO:0005184 | traceable author statement eclosion hormone activity ; GO:0008031 | non-traceable author statement eclosion hormone activity ; GO:0008031 | inferred from sequence or structural similarity "neuropeptide signaling pathway ; GO:0007218 | inferred from electronic annotation with InterPro:IPR006825 eclosion ; GO:0007562 | traceable author statement regulation of eclosion ; GO:0007563 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | traceable author statement ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from sequence model "EH, Drm-EH, eh, EHAB, DMEHAB, CG5400, Eh" IPR006825:Eclosion hormone CG5400 11-Aug-17 DroID_v2017_08 - - "Cele\clec-251, Cele\F11D11.6, Cele\clec-253, Cele\clec-255" - - - FBgn0030191 CG15306 - http://flybase.org/reports/FBgn0030191 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR027328 molecular_function ; GO:0003674 | no biological data available positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype - CG15306 "IPR001715:Calponin homology domain, IPR027328:Microtubule-associated protein RP/EB" CG15306 11-Aug-17 DroID_v2017_08 "Drer\mapre2, Drer\mapre1a, Drer\mapre3b, Drer\mapre3a, Drer\mapre1b" "Scer\CHS5, Scer\BIM1" "Cele\ebp-1, Cele\ebp-2, Cele\ebp-3" Xtro\mapre1 "Mmus\Dmp1, Mmus\Mapre3, Mmus\Mapre2, Mmus\Mapre1" "Hsap\MAPRE3, Hsap\DMP1, Hsap\MAPRE1, Hsap\MAPRE2" viable FBgn0035170 dpr20 defective proboscis extension response 20 http://flybase.org/reports/FBgn0035170 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG12191, Dpr-20, CT9818, dpr20, Dpr20" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold, IPR013151:Immunoglobulin" CG12191 11-Aug-17 DroID_v2017_08 "Drer\LOC100333196, Drer\LOC101885444, Drer\si:ch211-264f5.6, Drer\si:dkey-65b12.12, Drer\nadl1.1" - Cele\zig-8 "Xtro\obsl1, Xtro\nfasc" - - viable FBgn0004186 snRNA:U1:95Cb small nuclear RNA U1 at 95Cb http://flybase.org/reports/FBgn0004186 "FBgn0003915, FBgn0003918" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity "U1, U1 snRNA, U1a-95Cb, U1-95.2, U1snRNA, K5, snRNA:U1, snRNA-U1-95.2, U1snRNA95Cb, CR32866, snRNA:U1:95Cb, U1:95Cb, snRNA:U1:95CB, U1-95Cb, U1:95C, 95C U1" - CR32866 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063485 Lasp Lasp http://flybase.org/reports/FBgn0063485 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 protein binding ; GO:0005515 | inferred from physical interaction with Actn actin binding ; GO:0003779 | inferred from direct assay regulation of myofibril size ; GO:0014881 | inferred from mutant phenotype muscle thin filament assembly ; GO:0071689 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype positive regulation of pole plasm oskar mRNA localization ; GO:0045856 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype sperm individualization complex ; GO:0070864 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay A band ; GO:0031672 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG3849, cDNA B, anon-73Bd, Lasp, lasp" "IPR000900:Nebulin repeat, IPR001452:SH3 domain, IPR001781:Zinc finger, LIM-type" CG3849 11-Aug-17 DroID_v2017_08 "Drer\neb, Drer\nrap, Drer\lasp1, Drer\nebl, Drer\dbnlb" "Scer\ABP1, Scer\BOI1" "Cele\F42H10.3, Cele\dbn-1" "Xtro\nebl, Xtro\neb, Xtro\lasp1" "Mmus\Dbnl, Mmus\Nrap, Mmus\Lasp1, Mmus\Nebl, Mmus\Neb" "Hsap\LASP1, Hsap\NEB, Hsap\NEBL, Hsap\NRAP, Hsap\DBNL" "partially lethal - majority die,hatching behavior defective,decreased cell number,grandchildless,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,visible,viable,male sterile,female fertile,reduced" "pole cell,ectopic,hub cell,trichogen cell,mesothoracic tergum,investment cone,individualization stage spermatid" DRSC10379 EK -0.43576585 0.184164187 -0.940571665 1.503371166 2.30026385 0.235878809 FBgn0265010 Ms(3)88C Male sterile (3) 88C http://flybase.org/reports/FBgn0265010 gene - - - Ms(3)88C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084325 su(eas)13 su(eas)13 http://flybase.org/reports/FBgn0084325 gene - - - su(eas)13 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001529 l(1)11Ee lethal (1) 11Ee http://flybase.org/reports/FBgn0001529 - gene - - - l(1)11Ee - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016669 Hrp75 Hrp75 http://flybase.org/reports/FBgn0016669 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "hrp75, Hrp75" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031968 CG7231 - http://flybase.org/reports/FBgn0031968 protein_coding_gene - - - CG7231 IPR019356:Protein of unknown function DUF2181 CG7231 11-Aug-17 DroID_v2017_08 "Drer\fam151a, Drer\fam151b" - Cele\mnr-1 "Xtro\fam151a, Xtro\fam151b" "Mmus\Fam151b, Mmus\Fam151a" "Hsap\FAM151B, Hsap\FAM151A" "lethal,recessive,viable,fertile" FBgn0039616 CG11828 - http://flybase.org/reports/FBgn0039616 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006620, InterPro:IPR013547 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 CG11828 "IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain" CG11828 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\p4ha3, Drer\p4ha1a, Drer\p4ha2, Drer\zgc:152670, Drer\zgc:158254, Drer\p4htm" - "Cele\Y43F8B.19, Cele\phy-3, Cele\phy-4, Cele\C14E2.4, Cele\phy-2" "Xtro\p4ha1, Xtro\p4ha2, Xtro\p4ha3" "Mmus\P4htm, Mmus\P4ha2, Mmus\P4ha3, Mmus\P4ha1" "Hsap\P4HA2, Hsap\P4HTM, Hsap\P4HA3, Hsap\P4HA1" viable FBgn0041184 Socs36E Suppressor of cytokine signaling at 36E http://flybase.org/reports/FBgn0041184 protein_coding_gene protein kinase inhibitor activity ; GO:0004860 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from electronic annotation with InterPro:IPR028420 haltere development ; GO:0007482 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype notum morphogenesis ; GO:0048802 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | traceable author statement germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype negative regulation of sevenless signaling pathway ; GO:0045873 | inferred from genetic interaction with sev negative regulation of protein kinase activity ; GO:0006469 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 cytokine-mediated signaling pathway ; GO:0019221 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 long-term memory ; GO:0007616 | inferred from mutant phenotype negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from genetic interaction with Stat92E negative regulation of R7 cell differentiation ; GO:0045677 | inferred from genetic interaction with sev negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype cell dedifferentiation ; GO:0043697 | inferred from genetic interaction with bam compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 "CG15154, SOCS36E, socs36E, dmSocs36E, SOCS, socs60E1, Socs, dSOCS, clone 2.2, anon-EST:Liang-2.2, Socs36E, SocS36E, socs36e" "IPR000980:SH2 domain, IPR001496:SOCS box domain, IPR028420:Suppressor of cytokine signalling 5" CG15154 11-Aug-17 DroID_v2017_08 "Drer\socs4, Drer\cishb, Drer\socs7, Drer\socs3a, Drer\socs6b, Drer\socs6, Drer\socs1a, Drer\socs1b, Drer\socs5a, Drer\socs5b, Drer\socs9, Drer\socs2, Drer\cish, Drer\socs3b" - - "Xtro\socs3, Xtro\socs3, Xtro\socs4, Xtro\socs2, Xtro\socs6, Xtro\cish, Xtro\socs5, Xtro\socs1" "Mmus\Socs4, Mmus\Socs7, Mmus\Socs3, Mmus\Socs6, Mmus\Cish, Mmus\Socs1, Mmus\Socs5, Mmus\Socs2" "Hsap\SOCS7, Hsap\CISH, Hsap\SOCS1, Hsap\SOCS6, Hsap\SOCS5, Hsap\SOCS3, Hsap\SOCS2, Hsap\SOCS4" "visible,viable,fertile,male semi-sterile,lethal - all die before end of P-stage,partially,some die during pharate adult stage,short lived,memory defective,RU486 conditional" "anterior crossvein,wing vein,ectopic,eye,photoreceptor cell R7,supernumerary,cyst progenitor cell,male,male germline stem cell,somatic clone,border follicle cell,humerus,haltere,pigment cell,wing,germline cell" DRSC02455 IEK 0.507591113 -2.900628656 -1.232231707 2.41611484 -0.768366818 2.089294204 FBgn0034787 CG13535 - http://flybase.org/reports/FBgn0034787 protein_coding_gene - - - CG13535 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036433 CG9628 - http://flybase.org/reports/FBgn0036433 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9628 - CG9628 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0264656 paltry paltry http://flybase.org/reports/FBgn0264656 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - paltry - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0029715 CG11444 - http://flybase.org/reports/FBgn0029715 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:14634 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11444 "IPR019380:Casein kinase substrate, phosphoprotein PP28" CG11444 11-Aug-17 DroID_v2017_08 "Drer\pdap1b, Drer\pdap1a" - - Xtro\pdap1 Mmus\Pdap1 Hsap\PDAP1 viable FBgn0041707 7B2 7B2 http://flybase.org/reports/FBgn0041707 protein_coding_gene peptidase activator activity ; GO:0016504 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from electronic annotation with InterPro:IPR007945 positive regulation of peptidase activity ; GO:0010952 | inferred from direct assay positive regulation of proteolysis ; GO:0045862 | inferred from direct assay secretory granule ; GO:0030141 | inferred from electronic annotation with InterPro:IPR007945 "d7B2, CG1168, FBgn0040073, 7B2" IPR007945:Neuroendocrine 7B2 precursor CG1168 11-Aug-17 DroID_v2017_08 "Drer\scg5, Drer\scg5" - Cele\sbt-1 Xtro\scg5 Mmus\Scg5 Hsap\SCG5 viable FBgn0044496 DTD45.10 DTD45.10 http://flybase.org/reports/FBgn0044496 gene - - - DTD45.10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020418 I-element\RTase I element reverse transcriptase http://flybase.org/reports/FBgn0020418 FBgn0013982 transposable_element_gene "RNA-DNA hybrid ribonuclease activity ; GO:0004523 | inferred from electronic annotation with InterPro:IPR002156 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002156, InterPro:IPR012337" - - "ORF2, I\T, I-element\RTase, I-Factor ORF2, ORF2p" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase, IPR012337:Ribonuclease H-like domain, IPR002156:Ribonuclease H domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259110 mmd mind-meld http://flybase.org/reports/FBgn0259110 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001590, InterPro:IPR002870, InterPro:IPR006586" membrane protein ectodomain proteolysis ; GO:0006509 | inferred from sequence or structural similarity with HGNC:195 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:195 "mmd, CG42252, CG15603, CG15604, CT26192, CG9163" "IPR018358:Disintegrin, conserved site, IPR000742:EGF-like domain, IPR001590:Peptidase M12B, ADAM/reprolysin, IPR001762:Disintegrin domain, IPR002870:Peptidase M12B, propeptide, IPR006586:ADAM, cysteine-rich, IPR013032:EGF-like, conserved site, IPR034027:Reprolysin domain, adamalysin-type, IPR024079:Metallopeptidase, catalytic domain, IPR013111:EGF-like domain, extracellular" CG42252 11-Aug-17 DroID_v2017_08 "Drer\adam12, Drer\zgc:174164, Drer\adam17b, Drer\adam9, Drer\adam11, Drer\adam28, Drer\adam22, Drer\adam17a, Drer\adam19b, Drer\adam8a, Drer\adam19a, Drer\adam8b, Drer\adam15, Drer\adam23a" - "Cele\tag-275, Cele\unc-71, Cele\adm-4, Cele\K08B4.2, Cele\adm-2, Cele\F27D9.7" "Xtro\adam23, Xtro\adam11, Xtro\adam33, Xtro\adam12, Xtro\adam9" "Mmus\Adam26b, Mmus\Adam1a, Mmus\Adam24, Mmus\Adam19, Mmus\Adam39, Mmus\Adam17, Mmus\Adam15, Mmus\Adam6a, Mmus\Adam12, Mmus\Adam32, Mmus\Adam5, Mmus\Adam20, Mmus\Adam28, Mmus\Adam9, Mmus\Gm4787, Mmus\Adam11, Mmus\Adam3, Mmus\Adam4, Mmus\Adam34, Mmus\Adam22, Mmus\Gm5346, Mmus\Adam33, Mmus\Adam21, Mmus\Adamdec1, Mmus\Adam30, Mmus\Adam2, Mmus\Adam1b, Mmus\Adam25, Mmus\Adam7, Mmus\Adam26a, Mmus\Adam18, Mmus\Adam23, Mmus\Adam29, Mmus\Adam6b, Mmus\Adam8" "Hsap\ADAM8, Hsap\ADAM19, Hsap\ADAMDEC1, Hsap\ADAM11, Hsap\ADAM9, Hsap\ADAM18, Hsap\ADAM2, Hsap\ADAM21, Hsap\ADAM28, Hsap\ADAM23, Hsap\ADAM12, Hsap\ADAM33, Hsap\ADAM29, Hsap\ADAM22, Hsap\ADAM20, Hsap\ADAM17, Hsap\ADAM7, Hsap\ADAM32, Hsap\ADAM30, Hsap\ADAM15" DRSC20161 K 0.349532796 0.981301964 0.50742409 0.704442635 -1.675367721 -0.850084718 FBgn0265064 CR44175 - http://flybase.org/reports/FBgn0265064 non_protein_coding_gene - - - "CR44175, lincRNA.812" - CR44175 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052123 tRNA:CR32123:Psi transfer RNA:CR32123 pseudogene http://flybase.org/reports/FBgn0052123 pseudogene_attribute - - - "AE002602.trna21-LeuAAG, tRNA:L:AAG:AE002602, tRNA:CR32123:Psi, CR32123" - CR32123 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028635 ifm(2)RU7 indirect flight muscle (2) RU7 http://flybase.org/reports/FBgn0028635 gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay ifm(2)RU7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,flight defective,sterile,viable" "wing,dorsal medial muscle,indirect flight muscle & myofibril" FBgn0001385 l(1)2Bq lethal (1) 2Bq http://flybase.org/reports/FBgn0001385 - gene - - - l(1)2Bq - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036785 CG13700 - http://flybase.org/reports/FBgn0036785 protein_coding_gene - - - CG13700 - CG13700 11-Aug-17 DroID_v2017_08 - - Cele\pqn-8 - - - viable FBgn0065134 l(3)SH123 lethal (3) SH123 http://flybase.org/reports/FBgn0065134 gene - - - "l(3)SH123, l(2)SH3 123" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267305 CR45741 - http://flybase.org/reports/FBgn0267305 non_protein_coding_gene - - - CR45741 - CR45741 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261001 AGAR-53 Autosomal general anesthetic resistant 53 http://flybase.org/reports/FBgn0261001 gene - - - AGAR-53 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0038677 CG14284 - http://flybase.org/reports/FBgn0038677 protein_coding_gene - - - CG14284 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065678 l(2)SH0671 lethal (2) SH0671 http://flybase.org/reports/FBgn0065678 gene - - - "l(2)SH0671, l(2)SH2 0671" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028069 l(3)S090314 lethal (3) S090314 http://flybase.org/reports/FBgn0028069 gene - - - "0903/14, l(3)S090314" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,recessive" FBgn0084568 E-2fa Enhancer on chromosome 2-complementation group fa http://flybase.org/reports/FBgn0084568 gene - - - "E-2f, E-2fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020805 ms(3)1100A male sterile (3) 1100A http://flybase.org/reports/FBgn0020805 - gene - - - ms(3)1100A - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0083283 E(smoDN)2169 Enhancer of smoDN 2169 http://flybase.org/reports/FBgn0083283 gene - - - E(smoDN)2169 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022972 snRNP42K snRNP42K http://flybase.org/reports/FBgn0022972 - gene - - - "42K, snRNP42K" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027320 l(1)G0062 lethal (1) G0062 http://flybase.org/reports/FBgn0027320 - gene - - - l(1)G0062 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069165 mcl(3)Z1492 mcl(3)Z1492 http://flybase.org/reports/FBgn0069165 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1492 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0011916 tRNA:Met-CAT-1-2 transfer RNA:Methionine-CAT 1-2 http://flybase.org/reports/FBgn0011916 "FBgn0003807, FBgn0052844, FBgn0060139" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "CR32844, AE002787.trna22-MetCAT, tRNA:M:CAT:AE002787-b, tRNA:met2:48Bb, chr2R.trna81-MetCAT, tRNA-Met[CAU], tRNA-Met-CAT-1-2, tRNA:Met-CAT-1-2, tRNA:M2:48Bb" - CR32844 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065628 l(2)SH0791 lethal (2) SH0791 http://flybase.org/reports/FBgn0065628 gene - - - "l(2)SH0791, l(2)SH2 0791" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016834 l(1)MZ21 lethal (1) MZ21 http://flybase.org/reports/FBgn0016834 - gene - - - "l(1)MZ21, M21" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051876 Cpr30F Cuticular protein 30F http://flybase.org/reports/FBgn0051876 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype extracellular matrix ; GO:0031012 | inferred from sequence model "CG5879, Cpr30F, CG31876, DmelCpr30F" IPR000618:Insect cuticle protein CG31876 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0001774 l(1)M52 lethal (1) M52 http://flybase.org/reports/FBgn0001774 - gene - - - l(1)M52 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0051864 Qtzl Quetzalcoatl http://flybase.org/reports/FBgn0051864 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR010240 cysteine desulfurase activity ; GO:0031071 | inferred from electronic annotation with InterPro:IPR010240 [2Fe-2S] cluster assembly ; GO:0044571 | inferred from electronic annotation with InterPro:IPR010240 - "CG17749, CG31864, CG31864-PA, Qtzl" "IPR000192:Aminotransferase class V domain, IPR015424:Pyridoxal phosphate-dependent transferase, IPR010240:Cysteine desulfurase IscS, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1" CG31864 11-Aug-17 DroID_v2017_08 "Drer\scly, Drer\nfs1" Scer\NFS1 "Cele\B0205.6, Cele\F13H8.9" "Xtro\scly, Xtro\nfs1" "Mmus\Scly, Mmus\Nfs1" "Hsap\NFS1, Hsap\SCLY" "viable,sterile,recessive" FBgn0034792 YME1L - http://flybase.org/reports/FBgn0034792 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000642, InterPro:IPR005936 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000642, InterPro:IPR003959, InterPro:IPR003960" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000642 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005936 mitochondrion ; GO:0005739 | inferred from direct assay "DmCG3499, YME1L, dYME1L, CG3499" "IPR000642:Peptidase M41, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005936:Peptidase, FtsH, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3499 11-Aug-17 DroID_v2017_08 "Drer\yme1l1a, Drer\spg7, Drer\yme1l1b, Drer\afg3l2" "Scer\YTA12, Scer\AFG3, Scer\YME1" "Cele\ppgn-1, Cele\ymel-1, Cele\spg-7" Xtro\yme1l1 "Mmus\Spg7, Mmus\Afg3l2, Mmus\Yme1l1, Mmus\Afg3l1" "Hsap\AFG3L2, Hsap\YME1L1, Hsap\SPG7" "viable,visible" trichogen cell FBgn0033590 CG13217 - http://flybase.org/reports/FBgn0033590 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE32413, CG13217" - CG13217 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0045858 e(Pi3K92E)alpha e(Pi3K92E)alpha http://flybase.org/reports/FBgn0045858 gene - - - "alpha, e(Pi3K92E)alpha" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041597 l(2)PJ20 lethal (2) PJ20 http://flybase.org/reports/FBgn0041597 gene - - - l(2)PJ20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060311 l(3)S147912 lethal (3) S147912 http://flybase.org/reports/FBgn0060311 gene - - - "1479/12, l(3)S147912" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003568 su(lz[34]) suppressor of lozenge-34 http://flybase.org/reports/FBgn0003568 - gene - - - "su(lz[34k]), su(lz[34])" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female fertile,good" "female accessory gland,spermathecum,eye" FBgn0264397 FCP-E - http://flybase.org/reports/FBgn0264397 gene - - - FCP-E - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0052328 tRNA:Glu-CTC-3-2 transfer RNA:Glutamic acid-CTC 3-2 http://flybase.org/reports/FBgn0052328 tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "CR32328, AE002584.trna4-GluCTC, tRNA:E:CTC:AE002584-b, chr3L.trna4-GluCTC, tRNA:Glu-CTC-3-2, tRNA:CR32328, tRNA-Glu-CTC-3-2, GAG" - CR32328 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030262 Vago Vago http://flybase.org/reports/FBgn0030262 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG2081, BcDNA:RH70969, Vago, DIGF-2" IPR029277:Single domain Von Willebrand factor type C domain CG2081 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0051432 tRNA:Thr-TGT-2-5 transfer RNA:Threonine-TGT 2-5 http://flybase.org/reports/FBgn0051432 tRNA_gene ACA codon-amino acid adaptor activity ; GO:0033439 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033439 cytosol ; GO:0005829 | inferred by curator from GO:0033439 "AE002708.trna55-ThrTGT, tRNA[Thr][[3]], tRNA:thr3:87BC, tRNA:T3:87BC, tRNA:T:TGT:AE002708-b, CR31432, tRNA[[Thr]], chr3R.trna61-ThrTGT, tRNA-Thr-TGT-2-5, tRNA:Thr-TGT-2-5, tRNA:CR31432, ACA" - CR31432 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031455 Snapin SNAP associated protein http://flybase.org/reports/FBgn0031455 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Dysb intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR017246 neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity regulation of homeostatic process ; GO:0032844 | inferred from mutant phenotype synaptic vesicle priming ; GO:0016082 | non-traceable author statement BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:17145 synaptic vesicle ; GO:0008021 | inferred from direct assay synaptic vesicle ; GO:0008021 | non-traceable author statement "CG9958, CG32951, snapin, Dromel_CG9960_CG9958_FBtr007773_snapin_uORF, Snapin, NP_722835, SNAPIN" "IPR017246:Snapin, IPR028119:Snapin/Pallidin/Snn1" CG9958 11-Aug-17 DroID_v2017_08 Drer\snapin - Cele\snpn-1 Xtro\snapin Mmus\Snapin Hsap\SNAPIN "lethal - all die before end of pupal stage,some die during pupal stage,neurophysiology defective,drug conditional,female fertile" DRSC00736 E -0.117033922 0.993273659 1.590928682 0.825585157 0.007598632 -0.001642737 FBgn0052455 CG32455 - http://flybase.org/reports/FBgn0052455 protein_coding_gene - - - CG32455 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002752 mit(1)2 mitotic 2 http://flybase.org/reports/FBgn0002752 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0083048 snoRNA:Psi18S-1377d snoRNA:Psi18S-1377d http://flybase.org/reports/FBgn0083048 snoRNA_gene - - - "snoRNA:Psi18S-1377d, Psi18S-1377d, psi18S-1377d, CR34626, chr3R:26032931..26033021" - CR34626 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036192 Pldn Pallidin http://flybase.org/reports/FBgn0036192 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Blos1 eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype intracellular transport ; GO:0046907 | inferred from biological aspect of ancestor with PANTHER:PTN001583105 BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:8549 BLOC-1 complex ; GO:0031083 | inferred from biological aspect of ancestor with PANTHER:PTN001583105 transport vesicle ; GO:0030133 | inferred from biological aspect of ancestor with PANTHER:PTN001583105 extrinsic component of membrane ; GO:0019898 | inferred from biological aspect of ancestor with PANTHER:PTN001583105 "CG14133, Pallidin, NP_648494, pallidin, Pldn, pldn" "IPR017242:BLOC-1 complex, pallidin subunit, IPR028119:Snapin/Pallidin/Snn1" CG14133 11-Aug-17 DroID_v2017_08 Drer\bloc1s6 - - Xtro\bloc1s6 Mmus\Bloc1s6 Hsap\BLOC1S6 "eye color defective,viable" FBgn0067329 3F43 3F43 http://flybase.org/reports/FBgn0067329 gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3F43 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing sensillum,ectopic,somatic clone" FBgn0085540 CR40947 - http://flybase.org/reports/FBgn0085540 non_protein_coding_gene - - - "CR40947, CG40947" - CR40947 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263231 bel belle http://flybase.org/reports/FBgn0263231 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from mutant phenotype ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000005730 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from biological aspect of ancestor with PANTHER:PTN000619593 instar larval development ; GO:0002168 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay RISC complex ; GO:0016442 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "psg9, bel, BEL, CG9748, DmRH6, cg9748, cap, ms(3)neo30, l(3)85Ac, L3, anon-85Ab, ms(3)Pneo85A, l(3)L3, belle, l(3)S097074, l(3)S047110, l(3)L4740, Bel" "IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9748 11-Aug-17 DroID_v2017_08 "Drer\ddx3a, Drer\ddx3b" "Scer\MRH4, Scer\DBP1, Scer\DED1" "Cele\glh-1, Cele\vbh-1, Cele\glh-3, Cele\laf-1, Cele\glh-2" Xtro\ddx3x "Mmus\Ddx3x, Mmus\Ddx3y, Mmus\Ddx4, Mmus\D1Pas1" "Hsap\DDX3Y, Hsap\DDX3X, Hsap\DDX4" DRSC25066 IK -2.737597649 -0.844103717 -0.809998272 0.190823138 0.35739607 3.248510243 FBgn0051913 CG31913 - http://flybase.org/reports/FBgn0051913 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 structural constituent of ribosome ; GO:0003735 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 cytosolic large ribosomal subunit ; GO:0022625 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 "NEST:bs23g06, NEST:bs28e01, NEST:bs35c08, NEST:bs14h07, NEST:bs09g05, CG31913" IPR014807:Cytochrome oxidase assembly protein 1 CG31913 11-Aug-17 DroID_v2017_08 "Drer\coa1, Drer\rpl37" "Scer\RPL37A, Scer\RPL37B" "Cele\T23F2.2, Cele\Y38C1AA.14" Xtro\coa1 - Hsap\COA1 viable FBgn0026224 l(1)16Fq lethal (1) 16Fq http://flybase.org/reports/FBgn0026224 - gene - - - "ME-V, l(1)16Fq" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065653 l(2)SH0728 lethal (2) SH0728 http://flybase.org/reports/FBgn0065653 gene - - - "l(2)SH0728, l(2)SH2 0728" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259711 CG42365 - http://flybase.org/reports/FBgn0259711 protein_coding_gene - - - "CG42365, CG15675" - CG42365 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" FBgn0011060 l(1)Q13 lethal (1) Q13 http://flybase.org/reports/FBgn0011060 FBgn0010210 gene - - - l(1)Q13 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040553 CG14374 - http://flybase.org/reports/FBgn0040553 protein_coding_gene - - - CG14374 - CG14374 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010401 Os-C Os-C http://flybase.org/reports/FBgn0010401 - protein_coding_gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Os-c, OS-C, CG3250, Os-C" - CG3250 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " sacculus

, antennal segment 3

" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0058040 CG40040 - http://flybase.org/reports/FBgn0058040 protein_coding_gene - - - CG40040 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033729 Cpr49Af Cuticular protein 49Af http://flybase.org/reports/FBgn0033729 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr49Af, CG8510, DmelCpr49Af" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8510 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0037964 CG14731 - http://flybase.org/reports/FBgn0037964 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG14731, gi7299531, gi21483202" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG14731 11-Aug-17 DroID_v2017_08 - - "Cele\M03F8.5, Cele\F32D8.2, Cele\R03G8.1, Cele\F10C2.3, Cele\Y41E3.1, Cele\F07C3.3, Cele\F15H10.7, Cele\T23E1.1, Cele\R03G8.3, Cele\Y38A10A.2, Cele\K03A11.4, Cele\T07G12.3, Cele\F32G8.2, Cele\Y73F8A.35" - - - "viable,fertile" FBgn0002750 misp misstep http://flybase.org/reports/FBgn0002750 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available misp - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic segment" FBgn0046118 E(To)8 E(To)8 http://flybase.org/reports/FBgn0046118 gene - - - E(To)8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028214 l(3)S009720 lethal (3) S009720 http://flybase.org/reports/FBgn0028214 gene - - - "0097/20, l(3)S009720" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033865 CG6220 - http://flybase.org/reports/FBgn0033865 protein_coding_gene "transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from sequence or structural similarity with SGD:S000004410 transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000279609" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:16783 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex ; GO:0034402 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 histone modification ; GO:0016570 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 Cdc73/Paf1 complex ; GO:0016593 | inferred from sequence or structural similarity with SGD:S000004410 Cdc73/Paf1 complex ; GO:0016593 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:16783 CG6220 "IPR007852:Cdc73/Parafibromin, IPR031336:Cell division control protein 73, C-terminal, IPR032041:Paf1 complex subunit Cdc73, N-terminal domain" CG6220 11-Aug-17 DroID_v2017_08 Drer\cdc73 Scer\CDC73 Cele\cdc-73 Xtro\cdc73 Mmus\Cdc73 Hsap\CDC73 viable FBgn0011231 sdl seedless http://flybase.org/reports/FBgn0011231 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - sdl - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0032925 CG9246 - http://flybase.org/reports/FBgn0032925 protein_coding_gene transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 repressing transcription factor binding ; GO:0070491 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 negative regulation of histone acetylation ; GO:0035067 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with HGNC:24517 Noc2p-Noc3p complex ; GO:0030691 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 Noc1p-Noc2p complex ; GO:0030690 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 CG9246 "IPR005343:Nucleolar complex protein 2, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG9246 11-Aug-17 DroID_v2017_08 Drer\noc2l Scer\NOC2 Cele\pro-2 Xtro\noc2l Mmus\Noc2l Hsap\NOC2L "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0002789 Mp20 Muscle protein 20 http://flybase.org/reports/FBgn0002789 "FBgn0003740, FBgn0026854" protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity myoblast fusion ; GO:0007520 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of myoblast fusion ; GO:1901739 | inferred from mutant phenotype - "DMMP20, Dmmp20, CG4696, mp20, Tpn, Mp20, MP20" "IPR000557:Calponin repeat, IPR001715:Calponin homology domain, IPR003096:Smooth muscle protein/calponin" CG4696 11-Aug-17 DroID_v2017_08 "Drer\cnn2, Drer\cnn3b, Drer\cnn1b, Drer\tagln3b, Drer\tagln2, Drer\tagln, Drer\cnn3a, Drer\tagln3a, Drer\cnn1a, Drer\iqgap2" "Scer\SCP1, Scer\IQG1" "Cele\cpn-2, Cele\pes-7, Cele\cpn-1, Cele\cpn-3" "Xtro\tagln2, Xtro\cnn3, Xtro\cnn1, Xtro\tagln, Xtro\cnn2" "Mmus\Cnn2, Mmus\Iqgap1, Mmus\Iqgap3, Mmus\Cnn3, Mmus\Tagln2, Mmus\Cnn1, Mmus\Tagln, Mmus\Tagln3" "Hsap\CNN3, Hsap\CNN2, Hsap\TAGLN2, Hsap\TAGLN, Hsap\IQGAP1, Hsap\TAGLN3, Hsap\IQGAP3, Hsap\CNN1" " embryonic stage | 12-24 hr , adult stage , prepupal stage , pupal stage | early " adult stage synchronous muscle

"viable,visible" "dorsal acute muscle 1,nucleus | supernumeraryeve.eme,trichogen cell,supernumerary,tormogen cell,embryonic myoblast,dorsal transverse muscle,ventral acute muscle 2,segment border muscle,nucleushow-24B" FBgn0051675 CG31675 - http://flybase.org/reports/FBgn0051675 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE19849, CG31675" - CG31675 11-Aug-17 DroID_v2017_08 - - "Cele\C15H9.9, Cele\K11H12.6, Cele\K11H12.7" - - - viable FBgn0026380 Prosbeta3 Proteasome beta3 subunit http://flybase.org/reports/FBgn0026380 - protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 "proteasome core complex, beta-subunit complex ; GO:0019774 | inferred from electronic annotation with InterPro:IPR033811 proteasome core complex ; GO:0005839 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay" "Prosbeta3, CG11981, 11981, Beta-3, beta3, Pros beta3, beta-3" "IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR023333:Proteasome B-type subunit, IPR033811:Proteasome beta 3 subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG11981 11-Aug-17 DroID_v2017_08 "Drer\psmb3, Drer\p4hb" Scer\PUP3 Cele\pbs-3 Xtro\psmb3 Mmus\Psmb3 Hsap\PSMB3 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC16801 IE -3.090109855 -5.477058347 -3.845298976 -2.891937368 1.281761475 -0.036620931 FBgn0002206 l(3)67BDd lethal (3) 67BDd http://flybase.org/reports/FBgn0002206 - gene - - - l(3)67BDd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0014364 myoblast-specific myoblast specific http://flybase.org/reports/FBgn0014364 - gene - - - "mas, myoblast-specific" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040487 BobA Brother of Bearded A http://flybase.org/reports/FBgn0040487 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with neur Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype - "CG12487, bobA, Bob-A, Bob, BobA" - CG12487 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,lethal" "macrochaeta,microchaeta,external sensory organ precursor cell & dorsal mesothoracic disc-537.4,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B,tormogen cell,trichogen cell" FBgn0011660 Pms2 Pms2 http://flybase.org/reports/FBgn0011660 FBgn0024325 protein_coding_gene "mismatched DNA binding ; GO:0030983 | inferred from electronic annotation with InterPro:IPR002099, InterPro:IPR013507 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002099, InterPro:IPR013507, InterPro:IPR014790 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000008161 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000008161" mismatch repair ; GO:0006298 | inferred from biological aspect of ancestor with PANTHER:PTN000008161 MutLalpha complex ; GO:0032389 | inferred from biological aspect of ancestor with PANTHER:PTN000008284 microtubule associated complex ; GO:0005875 | inferred from direct assay "pms2, dmlh2, dmlh-2, dpms2, Mlh2, CG8169, Pms2" "IPR002099:DNA mismatch repair protein family, IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR013507:DNA mismatch repair protein, C-terminal, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR014762:DNA mismatch repair, conserved site, IPR014790:MutL, C-terminal, dimerisation, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR028831:DNA mismatch repair protein Pms1" CG8169 11-Aug-17 DroID_v2017_08 "Drer\pms2, Drer\pms1, Drer\rsph10b" "Scer\PMS1, Scer\MLH2" Cele\pms-2 "Xtro\rsph10b, Xtro\pms2, Xtro\pms1" "Mmus\Pms1, Mmus\Lef1, Mmus\Pms2" "Hsap\RSPH10B2, Hsap\PMS1, Hsap\PMS2, Hsap\LOC107984056, Hsap\LEF1, Hsap\RSPH10B" viable FBgn0267044 CG45488 - http://flybase.org/reports/FBgn0267044 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45488 - CG45488 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031873 Gas41 Gas41 http://flybase.org/reports/FBgn0031873 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype protein localization to heterochromatin ; GO:0097355 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with HGNC:7136 inferred from sequence or structural similarity with SGD:S000005051 inferred from sequence or structural similarity with SGD:S000006050 histone exchange ; GO:0043486 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with HGNC:7136 inferred from sequence or structural similarity with SGD:S000005051 inferred from sequence or structural similarity with SGD:S000006050 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24859 "GAS41, dGas41, CG9207, Gas41" IPR005033:YEATS CG9207 11-Aug-17 DroID_v2017_08 "Drer\mllt1a, Drer\mllt1b, Drer\mllt3, Drer\yeats4, Drer\yeats2" "Scer\SAS5, Scer\YAF9, Scer\TAF14" "Cele\gfl-1, Cele\Y105E8B.7" "Xtro\mllt3, Xtro\mllt1, Xtro\yeats2, Xtro\yeats4" "Mmus\Mllt3, Mmus\Yeats4, Mmus\Mllt1, Mmus\Yeats2" "Hsap\MLLT3, Hsap\YEATS2, Hsap\MLLT1, Hsap\YEATS4" viable FBgn0020608 anon-12Db anon-12Db http://flybase.org/reports/FBgn0020608 - gene - - - "D1, anon-12Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259332 C434.2 - http://flybase.org/reports/FBgn0259332 gene - - - C434.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing vein,wing hair,chaeta" FBgn0032613 CG13283 - http://flybase.org/reports/FBgn0032613 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718 - CG13283 "IPR024079:Metallopeptidase, catalytic domain, IPR000718:Peptidase M13" CG13283 11-Aug-17 DroID_v2017_08 "Drer\ece2b, Drer\ece1, Drer\phex, Drer\mmel1" - "Cele\nep-24, Cele\nep-6" "Xtro\ecel1, Xtro\ece1, Xtro\mmel1, Xtro\ece2" "Mmus\Phex, Mmus\Ecel1, Mmus\Ece1, Mmus\Mmel1, Mmus\Ece2, Mmus\Mme, Mmus\Kel" "Hsap\ECEL1, Hsap\MMEL1, Hsap\KEL, Hsap\PHEX, Hsap\ECE1, Hsap\MME, Hsap\ECE2" viable FBgn0060357 l(3)S140713a lethal (3) S140713a http://flybase.org/reports/FBgn0060357 gene - - - "1407/13, l(3)S140713a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0005138 l(2)74i lethal (2) 74i http://flybase.org/reports/FBgn0005138 - gene - - - l(2)74i - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037466 CG1965 - http://flybase.org/reports/FBgn0037466 protein_coding_gene "transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from biological aspect of ancestor with PANTHER:PTN000259143 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000259143" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR012890, InterPro:IPR022783 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG1965 "IPR012890:GC-rich sequence DNA-binding factor, IPR022783:GC-rich sequence DNA-binding factor domain" CG1965 11-Aug-17 DroID_v2017_08 "Drer\zgc:158234, Drer\gcfc2" - Cele\F43G9.12 "Xtro\paxbp1, Xtro\gcfc2" "Mmus\Paxbp1, Mmus\Gcfc2" "Hsap\PAXBP1, Hsap\GCFC2" lethal FBgn0035718 CG14820 - http://flybase.org/reports/FBgn0035718 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 protein binding ; GO:0005515 | inferred from physical interaction with egg "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG14820 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG14820 11-Aug-17 DroID_v2017_08 "Drer\cpa2, Drer\cpa6, Drer\cpa4, Drer\cpb2, Drer\cpo, Drer\cpa5, Drer\cpb1, Drer\cpa1" Scer\ECM14 "Cele\W01A8.6, Cele\ZC434.9, Cele\Y59C2A.1, Cele\F02D8.4, Cele\suro-1, Cele\Y47G6A.19, Cele\T06A4.3, Cele\T06A4.1, Cele\Y18H1A.9" "Xtro\cpa1, Xtro\LOC100487462, Xtro\LOC100489361, Xtro\cpo, Xtro\cpb1, Xtro\cpb2, Xtro\cpa3" "Mmus\Cpb2, Mmus\Cpa6, Mmus\Cpa4, Mmus\Cpa5, Mmus\Cpa2, Mmus\Cpb1, Mmus\Cpa3, Mmus\Cpa1" "Hsap\CPA5, Hsap\CPB1, Hsap\CPA2, Hsap\CPB2, Hsap\CPA6, Hsap\CPA3, Hsap\CPO, Hsap\CPA4, Hsap\CPA1" "partially lethal - majority die,some die during pupal stage" FBgn0035760 CG8607 - http://flybase.org/reports/FBgn0035760 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011060, InterPro:IPR013785" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR011060 - CG8607 "IPR005137:Membrane complex biogenesis protein, BtpA family, IPR011060:Ribulose-phosphate binding barrel" CG8607 11-Aug-17 DroID_v2017_08 Drer\zgc:162297 - "Cele\fipr-15, Cele\F13E9.13" Xtro\LOC549154 - - viable FBgn0052736 CG32736 - http://flybase.org/reports/FBgn0052736 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32736, CG14429, BcDNA:RE60462" IPR028183:Uncharacterised protein family UPF0640 CG32736 11-Aug-17 DroID_v2017_08 "Drer\smim4, Drer\si:ch211-68a17.7, Drer\lin37" - Cele\lin-37 Xtro\lin37 Mmus\Smim4 "Hsap\C12orf73, Hsap\LIN37, Hsap\SMIM4" FBgn0065673 l(2)SH0678 lethal (2) SH0678 http://flybase.org/reports/FBgn0065673 gene - - - "l(2)SH0678, l(2)SH2 0678" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263262 spa3 - http://flybase.org/reports/FBgn0263262 gene - gonad development ; GO:0008406 | inferred from mutant phenotype digestive tract mesoderm development ; GO:0007502 | inferred from mutant phenotype - spa3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "gonad,gonadal sheath proper primordium,visceral mesoderm" FBgn0070020 BG01020 BG01020 http://flybase.org/reports/FBgn0070020 gene - - - BG01020 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0261581 CG42691 - http://flybase.org/reports/FBgn0261581 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42691 - CG42691 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060809 l(3)S054908 lethal (3) S054908 http://flybase.org/reports/FBgn0060809 gene - - - "0549/08, l(3)S054908" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0051032 CR31032 - http://flybase.org/reports/FBgn0051032 pseudogene_attribute - - - "CG31032, BcDNA:GH15189, CR31032" - CR31032 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036614 Golgin104 Golgin 104 http://flybase.org/reports/FBgn0036614 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2 signal transducer activity ; GO:0004871 | non-traceable author statement - trans-Golgi network ; GO:0005802 | inferred from direct assay "CG4925, golgin-104, Golgin104" - CG4925 11-Aug-17 DroID_v2017_08 Drer\ccdc186 - "Cele\arrd-16, Cele\cccp-1" Xtro\ccdc186 Mmus\Ccdc186 "Hsap\SRRM5, Hsap\CCDC186" FBgn0011768 Fdh Formaldehyde dehydrogenase http://flybase.org/reports/FBgn0011768 FBgn0002986 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002328, InterPro:IPR014183 octanol dehydrogenase activity ; GO:0004552 | inferred from direct assay S-(hydroxymethyl)glutathione dehydrogenase activity ; GO:0051903 | inferred from direct assay alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from direct assay S-nitrosoglutathione reductase activity ; GO:0080007 | inferred from mutant phenotype" ethanol oxidation ; GO:0006069 | inferred from electronic annotation with InterPro:IPR014183 regulation of peptidyl-cysteine S-nitrosylation ; GO:2000169 | inferred from mutant phenotype regulation of nitric oxide metabolic process ; GO:0080164 | inferred by curator from GO:0080007 visual learning ; GO:0008542 | inferred from mutant phenotype alcohol metabolic process ; GO:0006066 | inferred by curator from GO:0004022 - "Fdh, ODH, Odh, CG6598, gfd/odh, ADHX, odh, gfd, GSNOR, ADHX_DROME, fdh" "IPR002328:Alcohol dehydrogenase, zinc-type, conserved site, IPR011032:GroES-like, IPR013149:Alcohol dehydrogenase, C-terminal, IPR013154:Alcohol dehydrogenase, N-terminal, IPR014183:Alcohol dehydrogenase class III, IPR016040:NAD(P)-binding domain" CG6598 11-Aug-17 DroID_v2017_08 "Drer\adh8a, Drer\zgc:77938, Drer\zgc:63568, Drer\adh5, Drer\adh8b" "Scer\SFA1, Scer\ADH5" Cele\H24K24.3 "Xtro\adh5, Xtro\adh1a, Xtro\adh1b, Xtro\adh7, Xtro\adh1c, Xtro\adh1" "Mmus\Adh1, Mmus\Adh7, Mmus\Adh6b, Mmus\Adh4, Mmus\Adh6a, Mmus\Adh5" "Hsap\ADH1C, Hsap\ADH1A, Hsap\ADH7, Hsap\ADH4, Hsap\ADH1B, Hsap\ADH5, Hsap\ADH6" larval stage--adult stage "memory defective,heat sensitive,electrophoretic variant,viable,fertile" FBgn0019909 afl autosomal female lethal http://flybase.org/reports/FBgn0019909 - gene - - - afl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0030004 CG10958 - http://flybase.org/reports/FBgn0030004 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10958 "IPR029440:Dynein regulatory complex protein 1, C-terminal" CG10958 11-Aug-17 DroID_v2017_08 Drer\drc1 Scer\VIK1 - Xtro\drc1 Mmus\Drc1 Hsap\DRC1 viable FBgn0060746 l(3)S065312b lethal (3) S065312b http://flybase.org/reports/FBgn0060746 gene - - - "0653/12, l(3)S065312b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037831 Cap-H2 Chromosome associated protein H2 http://flybase.org/reports/FBgn0037831 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with MRG15 chromatin binding ; GO:0003682 | inferred from direct assay "chromosome condensation ; GO:0030261 | inferred from electronic annotation with InterPro:IPR031739 chromosome separation ; GO:0051304 | inferred from mutant phenotype inferred from genetic interaction with glu, MRG15 inferred from genetic interaction with Cap-D3 chromosome organization ; GO:0051276 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype inferred from genetic interaction with MRG15 male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype" condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:25071 "CG14685, Cap-H2, CAP-H2, CapH2, dCap-H2, cap-H2" "IPR031737:Condensin-2 complex subunit H2, C-terminal, IPR031739:Condensin-2 complex subunit H2" CG14685 11-Aug-17 DroID_v2017_08 Drer\ncaph2 - Cele\kle-2 Xtro\ncaph2 Mmus\Ncaph2 Hsap\NCAPH2 "viable,fertile,meiotic cell cycle defective,male semi-fertile,male sterile" "spermatozoon,polytene chromosome & nurse cell,polytene chromosome & nurse cellExel6159),primary spermatocyte in meiotic prophase I,primary spermatocyte in meiotic anaphase I,polytene chromosome & larval salivary gland43B,polytene chromosome & larval salivary gland | conditional - heat sensitivehs.PB,polytene chromosome & larval salivary glandhs.PB,polytene chromosomehs.PU,embryonic/larval salivary gland | third instar larval stage,nuclear envelopehs.PU" FBgn0260741 CG3281 - http://flybase.org/reports/FBgn0260741 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG3281, anon-WO0140519.243, 87A7-9/1, anon-87Aa" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG3281 11-Aug-17 DroID_v2017_08 "Drer\znf131, Drer\zbtb18, Drer\si:ch211-79k12.2, Drer\zbtb14, Drer\patz1, Drer\si:dkeyp-121d2.7, Drer\bcl6ab, Drer\zbtb7a, Drer\si:ch211-119o8.6, Drer\zbtb24, Drer\zbtb17, Drer\e4f1, Drer\zbtb49" "Scer\AZF1, Scer\ZAP1" "Cele\C04F5.9, Cele\F56D1.1, Cele\Y55F3AM.14, Cele\row-1, Cele\blmp-1" "Xtro\zbtb11, Xtro\zbtb41, Xtro\znf238.2, Xtro\zbtb40, Xtro\zbtb14, Xtro\zbtb26, Xtro\hic1, Xtro\gzf1, Xtro\zbtb7c" "Mmus\Zbtb7a, Mmus\Zbtb42, Mmus\Zbtb7c, Mmus\Zbtb24, Mmus\Zbtb17, Mmus\Zbtb6, Mmus\Mynn, Mmus\Zbtb26, Mmus\Patz1, Mmus\Zfp599, Mmus\Zbtb48, Mmus\Zbtb14, Mmus\Zfp60, Mmus\Bcl6b, Mmus\Vezf1, Mmus\Zfp131, Mmus\Zbtb18, Mmus\Zbtb41, Mmus\Zbtb38, Mmus\Zbtb7b, Mmus\Gzf1" "Hsap\GZF1, Hsap\ZBTB17, Hsap\ZBTB7A, Hsap\PRDM5, Hsap\ZBTB6, Hsap\MYNN, Hsap\ZNF616, Hsap\ZBTB26, Hsap\ZNF131, Hsap\BCL6B, Hsap\ZBTB11, Hsap\ZBTB24, Hsap\ZNF415, Hsap\ZBTB48, Hsap\ZBTB7B, Hsap\ZBTB41, Hsap\PATZ1, Hsap\ZSCAN21, Hsap\ZNF208, Hsap\ZBTB14, Hsap\ZBTB7C, Hsap\ZBTB18" FBgn0030484 GstT4 Glutathione S transferase T4 http://flybase.org/reports/FBgn0030484 protein_coding_gene - biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GST-theta, CG1681, GstT4, gstt4, GSTT4, DmGSTT4" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG1681 11-Aug-17 DroID_v2017_08 "Drer\gstt1b, Drer\gstt2, Drer\eef1g, Drer\vars, Drer\mars, Drer\gstr, Drer\gstt1a, Drer\eef1e1" "Scer\CAM1, Scer\GTT2, Scer\TEF4, Scer\GTT1, Scer\YGR201C, Scer\URE2" "Cele\gst-37, Cele\gst-32, Cele\gst-34" "Xtro\eef1g, Xtro\gstt1, Xtro\eef1e1" "Mmus\Eef1e1, Mmus\Gstt4, Mmus\Gstt1, Mmus\Gstt2, Mmus\Eef1g, Mmus\Gstt3, Mmus\Vars, Mmus\Mars" "Hsap\GSTT2, Hsap\MARS, Hsap\GSTT2B, Hsap\EEF1E1, Hsap\EEF1G, Hsap\GSTT1, Hsap\VARS" "viable,fertile" FBgn0005130 l(1)X2 lethal (1) X2 http://flybase.org/reports/FBgn0005130 - gene - - - l(1)X2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic head,embryonic segment,mitotic cell cycle | gastrula stage" FBgn0000293 Cg42DE Collagen-like 42DE http://flybase.net/reports/FBgn0000293.html gene "Cg7, Collagen-like gene, DCg7" 11-Aug-17 DroID_v2017_08 FBgn0065319 l(2)SH1919 lethal (2) SH1919 http://flybase.org/reports/FBgn0065319 gene - - - "l(2)SH1919, l(2)SH2 1919, SH1919" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024262 acd(2)5M7 auditory courtship defective 5M7 http://flybase.org/reports/FBgn0024262 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5M7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective" FBgn0275434 CR46266 - http://flybase.org/reports/FBgn0275434 non_protein_coding_gene - - - CR46266 - CR46266 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032341 Reps RALBP1 associated Eps domain containing http://flybase.org/reports/FBgn0032341 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 protein binding ; GO:0005515 | inferred from physical interaction with Rlip - - "REPS, Reps, CG6192" "IPR000261:EH domain, IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG6192 11-Aug-17 DroID_v2017_08 "Drer\reps2, Drer\reps1" "Scer\END3, Scer\TAX4, Scer\SLA1, Scer\IRS4, Scer\PAN1, Scer\EDE1" Cele\reps-1 "Xtro\reps2, Xtro\eps15, Xtro\reps1, Xtro\eps15l1" "Mmus\Reps2, Mmus\Eps15l1, Mmus\Reps1" "Hsap\REPS2, Hsap\EPS15, Hsap\REPS1" viable FBgn0051760 CG31760 - http://flybase.org/reports/FBgn0051760 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR017978 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from biological aspect of ancestor with PANTHER:PTN002091395 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR017978 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN002091395 "CG17215, CG17214, BcDNA:RE52162, CG31760" "IPR017978:GPCR family 3, C-terminal" CG31760 11-Aug-17 DroID_v2017_08 "Drer\gpr158b, Drer\si:ch211-156l18.8, Drer\gpr158a" - Cele\F39B2.8 "Xtro\plgrkt, Xtro\gpr158" "Mmus\Gpr179, Mmus\Gpr158" "Hsap\GPR179, Hsap\GPR158" "viable,fertile" DRSC02590 K 0.711210242 -0.529050037 -1.223619393 -0.093090562 -0.324758179 2.060973629 FBgn0034985 CG3328 - http://flybase.org/reports/FBgn0034985 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR024061 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR008967" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR008967" - CG3328 "IPR008967:p53-like transcription factor, DNA-binding, IPR030392:Intramolecular chaperone auto-processing domain, IPR024061:NDT80 DNA-binding domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR026932:Myelin gene regulatory factor C-terminal domain 1" CG3328 11-Aug-17 DroID_v2017_08 Drer\myrf - "Cele\myrf-1, Cele\myrf-2" Xtro\myrf "Mmus\Myrf, Mmus\Myrfl" "Hsap\MYRFL, Hsap\MYRF" "viable,fertile" FBgn0044401 Scim26 Sensitized chromosome inheritance modifier 26 http://flybase.org/reports/FBgn0044401 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0266200 CR44895 - http://flybase.org/reports/FBgn0266200 non_protein_coding_gene - - - CR44895 - CR44895 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000406 Cyt-b5-r Cytochrome b5-related http://flybase.org/reports/FBgn0000406 - protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR012171 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 "lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804, InterPro:IPR012171" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012171 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "Cyt-b5, Cyt-b, TU-36B, Cytb, TU36B, Cytb5, CG13279, Cyt-b5-r, Cytb5r" "IPR018506:Cytochrome b5, heme-binding site, IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR005804:Fatty acid desaturase domain, IPR012171:Fatty acid desaturase" CG13279 11-Aug-17 DroID_v2017_08 "Drer\dpm3, Drer\fads2, Drer\cyb5a" - "Cele\fbxa-76, Cele\F58B4.2, Cele\C24H12.1, Cele\fat-4, Cele\T27A1.3, Cele\F49E11.8, Cele\fat-3" "Xtro\dpm3, Xtro\fads2" "Mmus\Fads2, Mmus\Dpm3, Mmus\Fads3, Mmus\Fads1, Mmus\4833423E24Rik" "Hsap\DPM3, Hsap\FADS3, Hsap\FADS1, Hsap\FADS2" " embryonic stage | stage 16 , pupal stage | late , larval stage&&adult stage " " larval visceral muscle

, tergosternal muscle

, skeletal muscle of leg

, embryonic/larval somatic muscle

" viable FBgn0003535 stop stopped http://flybase.org/reports/FBgn0003535 - gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - stop - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0034381 List Lithium-inducible SLC6 transporter http://flybase.org/reports/FBgn0034381 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT response to lithium ion ; GO:0010226 | inferred from mutant phenotype amino acid transmembrane import ; GO:0044745 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model "List, CG15088, DmNAT2" IPR000175:Sodium:neurotransmitter symporter CG15088 11-Aug-17 DroID_v2017_08 "Drer\zgc:158225, Drer\slc6a19a.1, Drer\slc6a11a, Drer\slc6a14, Drer\si:ch211-132b12.6, Drer\slc6a15, Drer\slc6a16a, Drer\slc6a19b, Drer\si:ch211-132b12.2, Drer\slc6a4a, Drer\slc6a2, Drer\slc6a8, Drer\si:ch211-132b12.1, Drer\zgc:174946, Drer\slc6a5, Drer\slc6a6a, Drer\si:ch211-132b12.3, Drer\slc6a18, Drer\slc6a13l, Drer\slc6a17, Drer\slc6a13, Drer\slc6a1l, Drer\slc6a6b, Drer\slc6a1a, Drer\slc6a13, Drer\slc6a4b, Drer\slc6a9, Drer\slc6a1b, Drer\slc6a16b, Drer\si:ch211-117c9.5" - "Cele\snf-9, Cele\mod-5, Cele\snf-5, Cele\snf-3, Cele\dat-1, Cele\snf-7, Cele\snf-12, Cele\snf-11, Cele\snf-6, Cele\snf-2" "Xtro\slc6a13, Xtro\slc6a8, Xtro\slc6a7, Xtro\slc6a17, Xtro\slc6a9, Xtro\slc6a19, Xtro\slc6a6, Xtro\slc6a16, Xtro\slc6a3, Xtro\slc6a15, Xtro\slc6a1, Xtro\slc6a2, Xtro\LOC100127682, Xtro\slc6a4, Xtro\slc6a14.2, Xtro\slc6a12, Xtro\slc6a5" "Mmus\Slc6a18, Mmus\Slc6a5, Mmus\Slc6a13, Mmus\Slc6a20a, Mmus\Slc6a17, Mmus\Slc6a7, Mmus\Slc6a1, Mmus\Slc6a11, Mmus\Slc6a19, Mmus\Slc6a20b, Mmus\Slc6a15, Mmus\Slc6a4, Mmus\Slc6a3, Mmus\Slc6a9, Mmus\Slc6a14, Mmus\Slc6a8, Mmus\Slc6a6, Mmus\Slc6a2, Mmus\Slc6a12" "Hsap\SLC6A17, Hsap\SLC6A18, Hsap\SLC6A20, Hsap\SLC6A19, Hsap\SLC6A2, Hsap\SLC6A7, Hsap\SLC6A14, Hsap\SLC6A13, Hsap\SLC6A9, Hsap\SLC6A11, Hsap\SLC6A3, Hsap\SLC6A15, Hsap\SLC6A5, Hsap\SLC6A4, Hsap\SLC6A12, Hsap\SLC6A8, Hsap\SLC6A1, Hsap\SLC6A6" "chemical sensitive,partially lethal - majority die,some die during pupal stage" FBgn0052826 tRNA:Pro-CGG-1-1 transfer RNA:Proline-CGG 1-1 http://flybase.org/reports/FBgn0052826 tRNA_gene CCG codon-amino acid adaptor activity ; GO:0033424 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033424 cytosol ; GO:0005829 | inferred by curator from GO:0033424 "AE002611.trna1-ProCGG, tRNA:P:CGG:AE002611, CR32826, chrX.trna15-ProCGG, tRNA-Pro-CGG-1-1, tRNA:Pro-CGG-1-1, tRNA:CR32826, CCG" - CR32826 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030605 ND-B18 NADH dehydrogenase (ubiquinone) B18 subunit http://flybase.org/reports/FBgn0030605 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR008698 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P17568 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P17568" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P17568 "NB8M, ND-B18, CG5548" "IPR008698:NADH:ubiquinone oxidoreductase, B18 subunit" CG5548 11-Aug-17 DroID_v2017_08 Drer\ndufb7 - Cele\D2030.4 Xtro\ndufb7 Mmus\Ndufb7 Hsap\NDUFB7 "visible,lethal - all die before end of pupal stage,some die during pupal stage" trichogen cell FBgn0267899 CR46187 - http://flybase.org/reports/FBgn0267899 pseudogene_attribute - - - "CR46187, CG12717-related" - CR46187 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037255 Fip1 Factor interacting with poly(A) polymerase 1 http://flybase.org/reports/FBgn0037255 protein_coding_gene myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A RNA binding ; GO:0003723 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000336935 pre-mRNA cleavage required for polyadenylation ; GO:0098789 | inferred from biological aspect of ancestor with PANTHER:PTN000336935 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000336935 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D nucleus ; GO:0005634 | inferred from direct assay mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000336935 "clone 1.35, anon-EST:Liang-1.35, Fip1, CG1078, dFip1, FIP1" "IPR002713:FF domain, IPR007854:Pre-mRNA polyadenylation factor Fip1" CG1078 11-Aug-17 DroID_v2017_08 "Drer\fip1l1a, Drer\fip1l1b" Scer\FIP1 Cele\fipp-1 Xtro\fip1l1 Mmus\Fip1l1 Hsap\FIP1L1 "lethal,viable" embryonic/larval brain DRSC12147 K 0.024469664 0.893397531 -0.60381522 -0.264861956 -2.183820967 -0.282578402 FBgn0036311 CG17666 - http://flybase.org/reports/FBgn0036311 protein_coding_gene - - - "bs31g10.y1, CG17666" - CG17666 11-Aug-17 DroID_v2017_08 - - "Cele\C04G6.7, Cele\C27A2.5, Cele\F29D10.2, Cele\T01B7.8, Cele\C04G6.10" - - - viable FBgn0003078 Ppb Photophobe http://flybase.org/reports/FBgn0003078 - gene - - - "Phb, Ppb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265994 CR44769 - http://flybase.org/reports/FBgn0265994 non_protein_coding_gene - - - "CR44769, lincRNA.187" - CR44769 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261611 CG42700 - http://flybase.org/reports/FBgn0261611 protein_coding_gene - - - "CG42700, CG13165, CG34233, ORE-16" IPR015943:WD40/YVTN repeat-like-containing domain CG42700 11-Aug-17 DroID_v2017_08 - - "Cele\H10D18.5, Cele\C01C4.2" - - - FBgn0061162 l(1)6C-166 lethal (1) 6C-166 http://flybase.org/reports/FBgn0061162 gene - - - "6C-166, l(1)6C-166" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262811 CG43182 - http://flybase.org/reports/FBgn0262811 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43182 - CG43182 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003584 su(t) suppressor of tan http://flybase.org/reports/FBgn0003584 - gene - - - su(t) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260274 GSd486 - http://flybase.org/reports/FBgn0260274 gene - - - GSd486 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0038131 CG15888 - http://flybase.org/reports/FBgn0038131 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15888 - CG15888 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261723 Dbx Dbx http://flybase.org/reports/FBgn0261723 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 axon guidance ; GO:0007411 | inferred from mutant phenotype neuron fate commitment ; GO:0048663 | inferred from mutant phenotype" - "Dbx, CG12361, dbx, dDbx, CG42234, CG13925" "IPR017970:Homeobox, conserved site, IPR009057:Homeobox domain-like, IPR001356:Homeobox domain, IPR000047:Helix-turn-helix motif" CG42234 11-Aug-17 DroID_v2017_08 "Drer\dbx1b, Drer\lbx2, Drer\barx2, Drer\tlx2, Drer\lbx1a, Drer\barhl2, Drer\nkx1.2lb, Drer\vox, Drer\tlx1, Drer\dbx2, Drer\ved, Drer\dbx1a, Drer\hlx1, Drer\LOC100008066, Drer\tlx3b, Drer\barx1, Drer\barhl1b, Drer\si:dkey-43p13.5, Drer\nkx6.1, Drer\pnx, Drer\lbx1b" - "Cele\ceh-51, Cele\egl-5" "Xtro\nkx1-1, Xtro\nkx6-3, Xtro\nkx6-2, Xtro\barhl2, Xtro\tlx3, Xtro\tlx1, Xtro\ventx1.2, Xtro\nkx1-2, Xtro\barhl1, Xtro\dbx1, Xtro\barx1, Xtro\tlx2, Xtro\hlx" "Mmus\Lbx2, Mmus\Barhl2, Mmus\Nkx6-2, Mmus\Tlx1, Mmus\Dbx2, Mmus\Nkx1-2, Mmus\Tlx2, Mmus\Barx1, Mmus\Sebox, Mmus\Barx2, Mmus\Nkx1-1, Mmus\Hlx, Mmus\Barhl1, Mmus\Tlx3, Mmus\Nkx6-3, Mmus\Dbx1, Mmus\Lbx1" "Hsap\BARHL2, Hsap\HLX, Hsap\BARX1, Hsap\LEUTX, Hsap\NKX1-1, Hsap\TLX2, Hsap\LBX2, Hsap\TLX1, Hsap\DBX2, Hsap\TLX3, Hsap\NKX6-3, Hsap\DBX1, Hsap\LBX1, Hsap\BARHL1, Hsap\BARX2" DRSC08271 K -0.30386415 0.964323143 -0.33257532 0.319406664 2.870977665 0.982165077 FBgn0262073 JC11 - http://flybase.org/reports/FBgn0262073 gene - response to anesthetic ; GO:0072347 | inferred from mutant phenotype - JC11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0003289 Rst(3)amd alpha methyl dopa-resistant on 3 http://flybase.org/reports/FBgn0003289 FBgn0004948 gene - - - "Amdr, Rst(3)amd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,chemical resistant,dominant" FBgn0067044 U14 U14 http://flybase.org/reports/FBgn0067044 gene - - - U14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective,lethal" "chaeta,pigment cell" FBgn0032860 CG15130 - http://flybase.org/reports/FBgn0032860 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "38C.48, CG15130" IPR032006:Transmembrane inner ear expressed protein CG15130 11-Aug-17 DroID_v2017_08 Drer\tmie - Cele\Y39A1C.1 - Mmus\Tmie Hsap\TMIE viable FBgn0266784 CR45249 - http://flybase.org/reports/FBgn0266784 non_protein_coding_gene - - - CR45249 - CR45249 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001420 l(1)6Dd lethal (1) 6Dd http://flybase.org/reports/FBgn0001420 - gene - - - l(1)6Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003074 Pgi Phosphoglucose isomerase http://flybase.org/reports/FBgn0003074 - protein_coding_gene glucose-6-phosphate isomerase activity ; GO:0004347 | inferred from mutant phenotype "gluconeogenesis ; GO:0006094 | inferred from electronic annotation with InterPro:IPR001672, InterPro:IPR018189 glycolytic process ; GO:0006096 | inferred from electronic annotation with InterPro:IPR001672, InterPro:IPR018189, InterPro:IPR023096" lipid particle ; GO:0005811 | inferred from direct assay "CG8251, GPI, pgi, Gpi, PGI, Pgi, gpi" "IPR018189:Phosphoglucose isomerase, conserved site, IPR001672:Phosphoglucose isomerase (PGI), IPR023096:Phosphoglucose isomerase, C-terminal" CG8251 11-Aug-17 DroID_v2017_08 "Drer\gpib, Drer\gpia" Scer\PGI1 Cele\gpi-1 Xtro\gpi Mmus\Gpi1 Hsap\GPI "electrophoretic variant,slow,viable,fertile,lethal,recessive" FBgn0003482 spn-D spindle D http://flybase.org/reports/FBgn0003482 "FBgn0047153, FBgn0051069" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR020588 DNA-dependent ATPase activity ; GO:0008094 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 endodeoxyribonuclease activity ; GO:0004520 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001415033 four-way junction DNA binding ; GO:0000400 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 oocyte fate determination ; GO:0030716 | inferred from mutant phenotype strand invasion ; GO:0042148 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 intracellular mRNA localization ; GO:0008298 | traceable author statement response to ionizing radiation ; GO:0010212 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype polarity specification of dorsal/ventral axis ; GO:0009951 | inferred from mutant phenotype microtubule organizing center organization ; GO:0031023 | inferred from mutant phenotype mitotic recombination ; GO:0006312 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 oogenesis ; GO:0048477 | traceable author statement oogenesis ; GO:0048477 | inferred from genetic interaction with fs(1)K10 meiotic DNA recombinase assembly ; GO:0000707 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with mus301 dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype polarity specification of anterior/posterior axis ; GO:0009949 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | traceable author statement karyosome formation ; GO:0030717 | inferred from mutant phenotype Rad51B-Rad51C-Rad51D-XRCC2 complex ; GO:0033063 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 replication fork ; GO:0005657 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 "spn-D, Spn-D, spnD, spndD, CG31069, BcDNA:RE19845, rad51C" "IPR013632:DNA recombination and repair protein Rad51-like, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020588:DNA recombination and repair protein RecA-like, ATP-binding domain" CG31069 11-Aug-17 DroID_v2017_08 "Drer\rad51c, Drer\xrcc3" "Scer\DMC1, Scer\RAD51, Scer\RAD55, Scer\RAD57" Cele\rad-51 "Xtro\rad51c, Xtro\xrcc3" "Mmus\Rad51b, Mmus\Xrcc3, Mmus\Rad51c" "Hsap\RAD51C, Hsap\RAD51B, Hsap\XRCC3" adult stage | female ovary

"viable,fertile,lethal" "chorion | maternal effect,karyosome,egg,dorsal,dorsal appendage,oocyte,nurse cell,synaptonemal complex,germline cyst,microtubule organizing center & oocyte,presumptive oocyte" FBgn0025393 CG14795 - http://flybase.org/reports/FBgn0025393 - protein_coding_gene - - - "EG:196F3.3, CG14795" - CG14795 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005232 l(3)R26 lethal of Roberts 26 http://flybase.org/reports/FBgn0005232 - gene - - - "l(3)26, l(3)R26" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0037280 CG1126 - http://flybase.org/reports/FBgn0037280 protein_coding_gene phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from sequence or structural similarity with HGNC:970 phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from biological aspect of ancestor with PANTHER:PTN000482504 cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:970 intracellular transport ; GO:0046907 | inferred from biological aspect of ancestor with PANTHER:PTN000482504 cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern BBSome ; GO:0034464 | inferred from biological aspect of ancestor with PANTHER:PTN000482504 BBSome ; GO:0034464 | inferred from sequence or structural similarity with HGNC:970 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN000482504 "CG1126, BBS5" "IPR006606:Bardet-Biedl syndrome 5 protein, IPR014003:DM16 repeat, IPR030804:Bardet-Biedl syndrome 5 protein/sex-determination protein fem-3, IPR011993:PH domain-like" CG1126 11-Aug-17 DroID_v2017_08 "Drer\klhl41a, Drer\klhl40a, Drer\bbs5, Drer\klhl41b, Drer\klhl40b" - "Cele\bbs-5, Cele\pafo-1" "Xtro\paf1, Xtro\klhl40, Xtro\bbs5, Xtro\klhl41" "Mmus\Bbs5, Mmus\Klhl41, Mmus\Paf1, Mmus\Klhl40" "Hsap\KLHL40, Hsap\PAF1, Hsap\KLHL41, Hsap\BBS5" viable DRSC12168 E 0.649027914 0.578822865 -1.670328423 0.470314141 0.340752514 0.129257066 FBgn0029184 E(Khc)ek2 E(Khc)ek2 http://flybase.org/reports/FBgn0029184 gene - - - E(Khc)ek2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030443 CG12715 - http://flybase.org/reports/FBgn0030443 protein_coding_gene - - - CG12715 IPR008166:Glycosyltransferase family 92 CG12715 11-Aug-17 DroID_v2017_08 "Drer\si:zfos-464b6.2, Drer\si:dkey-56i24.1, Drer\si:ch73-211l2.1, Drer\zgc:194839" - "Cele\ZK1025.4, Cele\C14C6.6, Cele\galt-1, Cele\C49A1.5, Cele\C18G1.7, Cele\Y47D3B.4, Cele\F36F12.3, Cele\C14C6.8, Cele\F13G3.3, Cele\ZK488.6, Cele\C31B8.7, Cele\F49C12.5, Cele\K06H6.4, Cele\C01G5.9, Cele\F28H7.7, Cele\ZK488.5, Cele\F46F5.7" "Xtro\LOC100492375, Xtro\LOC100145503, Xtro\LOC100495879" - - viable FBgn0032848 nesd nessun dorma http://flybase.org/reports/FBgn0032848 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from physical interaction with CHEBI:59521 female germline ring canal stabilization ; GO:0008335 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype midbody ; GO:0030496 | inferred from direct assay male germline ring canal ; GO:0035323 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay intercellular bridge ; GO:0045171 | inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay "38B.16, CG10722, nesd" "IPR011050:Pectin lyase fold/virulence factor, IPR012334:Pectin lyase fold" CG10722 11-Aug-17 DroID_v2017_08 Drer\shcbp1 - - Xtro\shcbp1 "Mmus\Shcbp1l, Mmus\Shcbp1" "Hsap\SHCBP1, Hsap\SHCBP1L" "viable,fertile,male semi-sterile,meiotic cell cycle defective,partially lethal - majority die" "onion stage spermatid,Nebenkern,contractile ring,cleavage furrow,spermatocyte ring canal,nurse cell ring canal,nurse cell" FBgn0065114 mfs(1)6E male-female-sterile in region 6E http://flybase.org/reports/FBgn0065114 gene - "regulation of female receptivity, post-mating ; GO:0046008 | inferred from mutant phenotype sperm storage ; GO:0046693 | inferred from mutant phenotype" - mfs(1)6E - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile" "male accessory gland,male accessory gland main cell" FBgn0035028 Start1 Start1 http://flybase.org/reports/FBgn0035028 protein_coding_gene cholesterol binding ; GO:0015485 | inferred from biological aspect of ancestor with PANTHER:PTN000253260 - - "CG3522, Start, Start1, start1, StART1" "IPR000799:Steroidogenic acute regulatory protein-like, IPR002913:START domain, IPR023393:START-like domain, IPR019498:MENTAL domain" CG3522 11-Aug-17 DroID_v2017_08 "Drer\star, Drer\LOC100331467, Drer\stard3, Drer\stard3nl, Drer\stard5" - "Cele\strl-1, Cele\tag-340" "Xtro\star, Xtro\stard3, Xtro\stard3nl" "Mmus\Stard5, Mmus\Stard3, Mmus\Stard3nl, Mmus\Star, Mmus\Stard6, Mmus\Acot12" "Hsap\STARD6, Hsap\STARD5, Hsap\STARD3, Hsap\STARD3NL, Hsap\STAR" viable FBgn0265918 CR44707 - http://flybase.org/reports/FBgn0265918 non_protein_coding_gene - - - "lincRNA.1015, CR44707" - CR44707 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046678 anon-38C.15 anon-38C.15 http://flybase.org/reports/FBgn0046678 gene - - - "38C.15, anon-38C.15" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263656 CG43647 - http://flybase.org/reports/FBgn0263656 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43647, mlncRNA42E5-1, lincRNA.258" - CG43647 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058005 CR40005 - http://flybase.org/reports/FBgn0058005 pseudogene_attribute - - - "CG40005, CR40005" - CR40005 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028856 CG18063 - http://flybase.org/reports/FBgn0028856 protein_coding_gene myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis - - "DS07486.5, BG:DS07486.5, CG18063" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site" CG18063 11-Aug-17 DroID_v2017_08 Drer\spata17 - - - Mmus\Spata17 Hsap\SPATA17 viable FBgn0040546 CG14705 - http://flybase.org/reports/FBgn0040546 protein_coding_gene - - - CG14705 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001415 l(1)3Ee lethal (1) 3Ee http://flybase.org/reports/FBgn0001415 - gene - - - "l(1)RC245, l(1)3Ee" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0067729 l(3)J1 lethal (3) J1 http://flybase.org/reports/FBgn0067729 gene - - - l(3)J1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083008 snoRNA:Psi28S-1135e snoRNA:Psi28S-1135e http://flybase.org/reports/FBgn0083008 snoRNA_gene - - - "snoRNA:Psi28S-1135e, Psi28S-1135e, psi28S-1135e, CR34601, chrX:16979721..16979820" - CR34601 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050058 CG30058 - http://flybase.org/reports/FBgn0050058 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30058 - CG30058 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051230 CG31230 - http://flybase.org/reports/FBgn0051230 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31230 - CG31230 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0259183 CG42287 - http://flybase.org/reports/FBgn0259183 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13353, CG42287" - CG42287 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036330 CG11263 - http://flybase.org/reports/FBgn0036330 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:H9IUR0 3'-5' exonuclease activity ; GO:0008408 | NOT inferred from sequence or structural similarity with UniProtKB:H9IUR0 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with UniProtKB:H9IUR0 - P granule ; GO:0043186 | inferred from sequence or structural similarity with UniProtKB:H9IUR0 CG11263 IPR012337:Ribonuclease H-like domain CG11263 11-Aug-17 DroID_v2017_08 Drer\exd1 - Cele\egal-1 Xtro\exd1 Mmus\Exd1 Hsap\EXD1 "partially lethal - majority die,some die during pupal stage" FBgn0060534 l(3)S100513 lethal (3) S100513 http://flybase.org/reports/FBgn0060534 gene - - - "1005/13, l(3)S100513" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0017427 anon-68Ea anon-68Ea http://flybase.org/reports/FBgn0017427 - gene - - - "T1, anon-68Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025157 ms(2)A10 ms(2)A10 http://flybase.org/reports/FBgn0025157 - gene - - - ms(2)A10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0262712 ifm(2)RS5 - http://flybase.org/reports/FBgn0262712 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0050212 tRNA:Arg-CCT-1-2 transfer RNA:Arginine-CCT 1-2 http://flybase.org/reports/FBgn0050212 tRNA_gene AGG codon-amino acid adaptor activity ; GO:0033448 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033448 cytosol ; GO:0005829 | inferred by curator from GO:0033448 "AE002787.trna2-ArgCCT, tRNA:R:CCT:AE002787-a, CR30133, CR30212, chr2R.trna60-ArgCCT, tRNA-Arg-CCT-1-2, tRNA:Arg-CCT-1-2, tRNA:CR30212, AGG" - CR30212 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005272 l(3)SG92 lethal (3) SG92 http://flybase.org/reports/FBgn0005272 - gene - - - l(3)SG92 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031126 Cyp6v1 Cyp6v1 http://flybase.org/reports/FBgn0031126 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "6v1, CG1829, Cyp6v1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG1829 11-Aug-17 DroID_v2017_08 "Drer\tbxas1, Drer\cyp3c2, Drer\cyp3a65, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp3c4" Scer\ERG11 "Cele\cyp-13A1, Cele\cyp-13A12, Cele\cyp-43A1, Cele\cyp-13A4, Cele\cyp-44A1, Cele\cyp-13A7, Cele\cyp-25A2, Cele\cyp-13A8, Cele\cyp-13A10, Cele\cyp-13A2, Cele\cyp-25A1, Cele\cyp-13B2, Cele\cyp-13A5, Cele\cyp-25A6, Cele\cyp-13A3, Cele\cyp-13A11, Cele\cyp-25A3, Cele\cyp-13A6, Cele\cyp-13B1, Cele\cyp-25A4" "Xtro\tbxas1, Xtro\LOC100494419, Xtro\cyp3a4, Xtro\cyp3a5" "Mmus\Cyp3a59, Mmus\Cyp3a41a, Mmus\Cyp3a41b, Mmus\Tbxas1, Mmus\Cyp3a25, Mmus\Cyp3a44, Mmus\Cyp3a57, Mmus\Cyp3a16, Mmus\Cyp3a13, Mmus\Cyp3a11" "Hsap\CYP3A5, Hsap\CYP3A7, Hsap\TBXAS1, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A4, Hsap\CYP3A43" "viable,fertile" FBgn0000225 Bsb Blunt short bristle http://flybase.org/reports/FBgn0000225 - gene molecular_function ; GO:0003674 | no biological data available antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Bsb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive,viable,fertile" "macrochaeta,arista,arista lateral,actin filament & arista,microtubule & arista" FBgn0015922 cln clown http://flybase.org/reports/FBgn0015922 - gene - compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with aos - cln - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,eye color defective,recessive,visible,fertile,female fertile,male fertile" "eye,ommatidium,pigment cell,secondary pigment cell,ectopic,tertiary pigment cell,cone cell,eye disc & photoreceptor cell,photoreceptor cell,lens,dorsal compartment" FBgn0029864 CG15894 - http://flybase.org/reports/FBgn0029864 protein_coding_gene - - - CG15894 - CG15894 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0040705 ND-B8 NADH dehydrogenase (ubiquinone) B8 subunit http://flybase.org/reports/FBgn0040705 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from biological aspect of ancestor with PANTHER:PTN000306062 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O43678 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O43678" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000306062 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O43678 "CG15434, NI8M, ND-B8" "IPR007741:Ribosomal protein/NADH dehydrogenase domain, IPR016464:NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2, IPR012336:Thioredoxin-like fold" CG15434 11-Aug-17 DroID_v2017_08 Drer\ndufa2 Scer\MRPL51 Cele\Y63D3A.7 "Xtro\ndufa2, Xtro\LOC100495196" Mmus\Ndufa2 Hsap\NDUFA2 "viable,visible,planar polarity defective" mesothoracic tergum FBgn0264698 CR43967 - http://flybase.org/reports/FBgn0264698 non_protein_coding_gene - - - CR43967 - CR43967 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013910 Dtf-1 Dtf-1 http://flybase.org/reports/FBgn0013910 - gene - - - "DTF-1, Dtf-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025160 l(2)GA339 lethal (2) GA339 http://flybase.org/reports/FBgn0025160 - gene - - - "GA339, l(2)GA339" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" ganglion mother cell GMC4-2a FBgn0262105 CR42858 - http://flybase.org/reports/FBgn0262105 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype - CR42858 - CR42858 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053483 CG33483 - http://flybase.org/reports/FBgn0053483 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33483 IPR010512:Protein of unknown function DUF1091 CG33483 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0260366 GSd234 - http://flybase.org/reports/FBgn0260366 gene - - - GSd234 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011659 Mlh1 Mlh1 http://flybase.org/reports/FBgn0011659 - protein_coding_gene "mismatched DNA binding ; GO:0030983 | inferred from electronic annotation with InterPro:IPR002099, InterPro:IPR013507 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002099, InterPro:IPR013507 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000008161 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000008161" mismatch repair ; GO:0006298 | inferred from biological aspect of ancestor with PANTHER:PTN000008161 MutLalpha complex ; GO:0032389 | inferred from biological aspect of ancestor with PANTHER:PTN000008164 synaptonemal complex ; GO:0000795 | inferred from biological aspect of ancestor with PANTHER:PTN000008164 chiasma ; GO:0005712 | inferred from biological aspect of ancestor with PANTHER:PTN000008164 "dmlh1, dmlh-1, CG11482, Mlh1" "IPR002099:DNA mismatch repair protein family, IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR013507:DNA mismatch repair protein, C-terminal, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR014762:DNA mismatch repair, conserved site, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR032189:DNA mismatch repair protein Mlh1, C-terminal" CG11482 11-Aug-17 DroID_v2017_08 Drer\mlh1 Scer\MLH1 Cele\mlh-1 Xtro\mlh1 Mmus\Mlh1 Hsap\MLH1 viable FBgn0052745 CR32745 - http://flybase.org/reports/FBgn0052745 pseudogene_attribute - - - "CG32745, CR32745" - CR32745 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037513 pyd3 pyd3 http://flybase.org/reports/FBgn0037513 protein_coding_gene beta-ureidopropionase activity ; GO:0003837 | inferred from direct assay 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from genetic interaction with r pyrimidine nucleobase catabolic process ; GO:0006208 | inferred by curator from GO:0003837 - "CG3027, pyd3, betaASase, betaAS" IPR003010:Carbon-nitrogen hydrolase CG3027 11-Aug-17 DroID_v2017_08 Drer\upb1 - Cele\upb-1 Xtro\upb1 Mmus\Upb1 Hsap\UPB1 "viable,fertile" FBgn0263133 mEFG1 mitochondrial translation elongation factor G 1 http://flybase.org/reports/FBgn0263133 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR004540, InterPro:IPR005225, InterPro:IPR005517 translation elongation factor activity ; GO:0003746 | inferred from biological aspect of ancestor with PANTHER:PTN002462392 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with UniProtKB:Q96RP9 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with UniProtKB:Q96RP9 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN002462392" mitochondrial translational elongation ; GO:0070125 | inferred from sequence or structural similarity with UniProtKB:Q96RP9 mitochondrial translational elongation ; GO:0070125 | inferred from biological aspect of ancestor with PANTHER:PTN000563009 nucleus ; GO:0005634 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CG4567, dEF-G1, GFM1, G, l(2)27Ea, B, l(2)27Cb, ico, mEFG1" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR009022:Elongation factor G, III-V domain, IPR009000:Translation protein, beta-barrel domain, IPR005517:Translation elongation factor EFG/EF2, domain IV, IPR005225:Small GTP-binding protein domain, IPR004540:Translation elongation factor EFG/EF2, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR000795:Transcription factor, GTP-binding domain, IPR000640:Translation elongation factor EFG, V domain, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR031157:Tr-type G domain, conserved site" CG4567 11-Aug-17 DroID_v2017_08 "Drer\gfm1, Drer\gfm2" "Scer\MEF1, Scer\MEF2" "Cele\gfm-1, Cele\Y119D3B.14, Cele\F58G1.8" "Xtro\gfm1, Xtro\gfm2" "Mmus\Gfm2, Mmus\Gfm1" "Hsap\GFM1, Hsap\GFM2" FBgn0050108 CG30108 - http://flybase.org/reports/FBgn0050108 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN000481815 CG30108 IPR007918:Mitochondrial distribution/morphology family 35/apoptosis CG30108 11-Aug-17 DroID_v2017_08 Drer\triap1 Scer\MDM35 Cele\T09A5.7 Xtro\triap1 Mmus\Triap1 Hsap\TRIAP1 "viable,fertile" FBgn0262114 RanBPM Ran-binding protein M http://flybase.org/reports/FBgn0262114 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from sequence or structural similarity with HGNC:13727 larval feeding behavior ; GO:0030536 | inferred from mutant phenotype germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype JAK-STAT cascade ; GO:0007259 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "RanBPM, CG42236, CG11763, l(2)k05201" "IPR024964:CTLH/CRA C-terminal to LisH motif domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001870:B30.2/SPRY domain, IPR006594:LIS1 homology motif, IPR013144:CRA domain, IPR006595:CTLH, C-terminal LisH motif, IPR003877:SPRY domain" CG42236 11-Aug-17 DroID_v2017_08 "Drer\ranbp10, Drer\spryd3, Drer\ranbp9" "Scer\SSH4, Scer\EAR1, Scer\VID30" "Cele\tag-304, Cele\Y54E5A.7" "Xtro\ranbp9, Xtro\spryd3" "Mmus\Ranbp9, Mmus\Ranbp10, Mmus\Spryd3" "Hsap\SPRYD3, Hsap\RANBP10, Hsap\RANBP9" FBgn0026165 schmalspur schmalspur http://flybase.org/reports/FBgn0026165 - gene molecular_function ; GO:0003674 | no biological data available central nervous system development ; GO:0007417 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "sur, schmalspur" - - 11-Aug-17 DroID_v2017_08 - - - - - - "commissure,midline glial cell,presumptive embryonic/larval central nervous system,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron" FBgn0266651 CR45158 - http://flybase.org/reports/FBgn0266651 non_protein_coding_gene - - - CR45158 - CR45158 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266220 CR44915 - http://flybase.org/reports/FBgn0266220 non_protein_coding_gene - - - CR44915 - CR44915 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025107 Brg-P9 Brg-P9 http://flybase.org/reports/FBgn0025107 - gene - - - Brg-P9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069334 UY4766 UY4766 http://flybase.org/reports/FBgn0069334 gene - - - UY4766 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell,mushroom body gamma-lobe" FBgn0262372 mir-3 mir-3 stem loop http://flybase.org/reports/FBgn0262372 miRNA_gene - - - "mir-3, 3, miR-3, CR42890, CR33037" - CR42890 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | 0-12 hr "viable,lethal,lethal - all die before end of pupal stage,some die during pupal stage" wing FBgn0039558 BCAS2 BCAS2 http://flybase.org/reports/FBgn0039558 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "mRNA processing ; GO:0006397 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" Prp19 complex ; GO:0000974 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG4980, BCAS2, dBCAS2" IPR008409:Pre-mRNA-splicing factor SPF27 CG4980 11-Aug-17 DroID_v2017_08 Drer\bcas2 - Cele\T12A2.7 Xtro\bcas2 Mmus\Bcas2 Hsap\BCAS2 "viable,visible,body color defective,increased cell death,lethal" "trichogen cell,mesothoracic tergum,wing,scutellum,chaeta,wing disc,posterior compartment" FBgn0058165 CG40165 - http://flybase.org/reports/FBgn0058165 protein_coding_gene - - - CG40165 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259345 EP-990 - http://flybase.org/reports/FBgn0259345 gene - - - EP-990 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta,ectopic" FBgn0044389 Scim5 Sensitized chromosome inheritance modifier 5 http://flybase.org/reports/FBgn0044389 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0022344 CG10340 - http://flybase.org/reports/FBgn0022344 - protein_coding_gene - mitochondrial proton-transporting ATP synthase complex assembly ; GO:0033615 | inferred from biological aspect of ancestor with PANTHER:PTN000319591 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000319591 "anon2A5, anon-EST:fe2A5, CG10340" IPR010591:ATP11 CG10340 11-Aug-17 DroID_v2017_08 Drer\atpaf1 Scer\ATP11 - Xtro\atpaf1 Mmus\Atpaf1 Hsap\ATPAF1 "viable,fertile" FBgn0085786 CR41501 - http://flybase.org/reports/FBgn0085786 pseudogene_attribute - - - CR41501 - CR41501 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037879 scpr-C SCP-containing protein C http://flybase.org/reports/FBgn0037879 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "SCPR-C, CG5106, BEST:CK01680, scpr-C, Scpr-C, scp-C, cg5106" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG5106 11-Aug-17 DroID_v2017_08 "Drer\r3hdml, Drer\glipr2, Drer\glipr2l, Drer\glipr1b, Drer\LOC101883528, Drer\crispld1b, Drer\LOC100536500, Drer\pi15b, Drer\pi15a, Drer\crispld1a, Drer\crispld2" "Scer\PRY2, Scer\PRY3, Scer\PRY1" "Cele\scl-6, Cele\scl-21, Cele\scl-2, Cele\scl-7, Cele\scl-14, Cele\scl-1, Cele\scl-20, Cele\scl-9, Cele\scl-19, Cele\scl-12, Cele\scl-10, Cele\scl-11, Cele\scl-18, Cele\scl-15, Cele\vap-2, Cele\scl-23, Cele\scl-8, Cele\scl-17, Cele\scl-3, Cele\scl-5, Cele\scl-13" "Xtro\MGC108118, Xtro\glipr2, Xtro\crispld2, Xtro\pi15, Xtro\crisp1, Xtro\crisp2, Xtro\r3hdml, Xtro\crisp3" "Mmus\Glipr1, Mmus\Glipr1l1, Mmus\Glipr1l2, Mmus\Pi16, Mmus\Pi15, Mmus\R3hdml, Mmus\Crispld2, Mmus\Crisp1, Mmus\Glipr2, Mmus\Crispld1, Mmus\Crisp4, Mmus\Clec18a, Mmus\Crisp2, Mmus\Crisp3" "Hsap\CRISPLD2, Hsap\GLIPR2, Hsap\CRISP1, Hsap\R3HDML, Hsap\GLIPR1L1, Hsap\CRISPLD1, Hsap\GLIPR1, Hsap\CLEC18A, Hsap\CLEC18B, Hsap\PI16, Hsap\CRISP2, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\PI15" viable FBgn0034863 SkpF SKP1-related F http://flybase.org/reports/FBgn0034863 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000002736 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with SGD:S000002736 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with SGD:S000002736 "CG12227, Skp, SkpF, skpF" "IPR011333:SKP1/BTB/POZ domain, IPR001232:S-phase kinase-associated protein 1-like, IPR016072:SKP1 component, dimerisation, IPR016073:SKP1 component, POZ domain, IPR016897:S-phase kinase-associated protein 1" CG12227 11-Aug-17 DroID_v2017_08 Drer\skp1 "Scer\SKP1, Scer\ELC1" "Cele\skr-6, Cele\skr-18, Cele\skr-20, Cele\skr-15, Cele\skr-10, Cele\skr-9, Cele\skr-21, Cele\skr-13, Cele\skr-16, Cele\skr-19, Cele\skr-7, Cele\skr-5, Cele\skr-17, Cele\skr-3, Cele\skr-14, Cele\skr-1, Cele\skr-8, Cele\skr-4, Cele\skr-12, Cele\skr-2" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 FBgn0063388 snoRNA:U27:54Ea snoRNA:U27:54Ea http://flybase.org/reports/FBgn0063388 snoRNA_gene - - - "U27snoRNA, CR32892, snoRNA:U27:54Ea" - CR32892 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005725 l(1)TK135 lethal (1) TK135 http://flybase.org/reports/FBgn0005725 - gene - - - "l135, l(1)TK135" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259566 GG01373 - http://flybase.org/reports/FBgn0259566 gene - - - GG01373 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "antennal segment,wing" FBgn0004754 l(3)89Bg lethal (3) 89Bg http://flybase.org/reports/FBgn0004754 - gene - - - l(3)89Bg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0021928 l(2)k11118 lethal (2) k11118 http://flybase.org/reports/FBgn0021928 - gene - - - l(2)k11118 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265496 CR44365 - http://flybase.org/reports/FBgn0265496 non_protein_coding_gene - - - "CR44365, lincRNA.303" - CR44365 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065476 l(2)SH1305 lethal (2) SH1305 http://flybase.org/reports/FBgn0065476 gene - - - "l(2)SH1305, l(2)SH2 1305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032361 CG6488 - http://flybase.org/reports/FBgn0032361 protein_coding_gene molecular_function ; GO:0003674 | no biological data available intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000480807 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000004536 Golgi transport complex ; GO:0017119 | inferred from direct assay "CG6488, Cog8" "IPR007255:Conserved oligomeric Golgi complex subunit 8, IPR016632:Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae, IPR016159:Cullin repeat-like-containing domain" CG6488 11-Aug-17 DroID_v2017_08 Drer\cog8 Scer\COG8 Cele\cogc-8 Xtro\cog8 Mmus\Cog8 Hsap\COG8 "viable,fertile" FBgn0060673 l(3)S077801 lethal (3) S077801 http://flybase.org/reports/FBgn0060673 gene - - - "0778/01, l(3)S077801" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061167 l(1)20BC lethal (1) 20BC http://flybase.org/reports/FBgn0061167 gene - - - l(1)20BC - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002475 l(3)SG30 lethal (3) SG30 http://flybase.org/reports/FBgn0002475 - gene - - - "SG30, l(3)SG30" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye-antennal disc FBgn0085453 CG34424 - http://flybase.org/reports/FBgn0085453 protein_coding_gene 5-formyltetrahydrofolate cyclo-ligase activity ; GO:0030272 | inferred from sequence or structural similarity with UniProtKB:P80405 5-formyltetrahydrofolate cyclo-ligase activity ; GO:0030272 | inferred from biological aspect of ancestor with PANTHER:PTN000601268 tetrahydrofolate interconversion ; GO:0035999 | inferred from biological aspect of ancestor with PANTHER:PTN000601268 folic acid-containing compound biosynthetic process ; GO:0009396 | inferred from biological aspect of ancestor with PANTHER:PTN000601268 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P80405 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000601269 "CG34424, anon-WO0118547.139, CG11079" IPR002698:5-formyltetrahydrofolate cyclo-ligase CG34424 11-Aug-17 DroID_v2017_08 Drer\mthfs Scer\FAU1 Cele\Y106G6E.4 Xtro\mthfs "Mmus\Mthfs, Mmus\Mthfsl" "Hsap\ST20-MTHFS, Hsap\MTHFS" viable FBgn0065505 l(2)SH1197 lethal (2) SH1197 http://flybase.org/reports/FBgn0065505 gene - - - "l(2)SH1197, l(2)SH2 1197" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021901 l(2)k12408 lethal (2) k12408 http://flybase.org/reports/FBgn0021901 - gene - - - l(2)k12408 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030052 CG12065 - http://flybase.org/reports/FBgn0030052 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000845 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG12065 "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR000845:Nucleoside phosphorylase domain" CG12065 11-Aug-17 DroID_v2017_08 - - Cele\H14E04.2 - - - "viable,fertile,visible" "chaeta,supernumerary" FBgn0264282 Su(Mir)3C2-1 - http://flybase.org/reports/FBgn0264282 gene - - - Su(Mir)3C2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053100 eIF4EHP eukaryotic translation initiation factor 4E homologous protein http://flybase.org/reports/FBgn0053100 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR001040 protein binding ; GO:0005515 | inferred from physical interaction with brat translation repressor activity ; GO:0030371 | inferred from genetic interaction with bcd RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with bcd eukaryotic initiation factor 4G binding ; GO:0031370 | NOT inferred from direct assay translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR001040 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype positive regulation of ecdysteroid biosynthetic process ; GO:0045998 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from genetic interaction with bcd imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001040 "4EHP, eIF4E-8, CG33100, d4EHP, CG10716, CT30033, 4E-HP, eIF4EHP" "IPR001040:Translation Initiation factor eIF- 4e, IPR023398:Translation Initiation factor eIF- 4e-like" CG33100 11-Aug-17 DroID_v2017_08 "Drer\eif4e2rs1, Drer\eif4e2" Scer\CDC33 Cele\ife-4 Xtro\eif4e2 Mmus\Eif4e2 Hsap\EIF4E2 "viable,fertile,behavior defective,recessive,partially lethal - majority die,maternal effect,some die during embryonic stage,lethal,neuroanatomy defective,visible,some die during pupal stage" "embryonic head segment,maternal effect,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0265625 CG44433 - http://flybase.org/reports/FBgn0265625 protein_coding_gene - - - "CG15086, CG44433" - CG44433 11-Aug-17 DroID_v2017_08 - - Cele\Y32B12B.4 - - - FBgn0260807 EP3-980 - http://flybase.org/reports/FBgn0260807 gene - - - EP3-980 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004719 ads all discs small http://flybase.org/reports/FBgn0004719 - gene - - - "l(3)ry100, l(3)ds16, ads" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267617 CR45955 - http://flybase.org/reports/FBgn0267617 non_protein_coding_gene - - - CR45955 - CR45955 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023213 eIF4G1 eukaryotic translation initiation factor 4G1 http://flybase.org/reports/FBgn0023213 - protein_coding_gene "translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC:3296,SGD:S000003394 eukaryotic initiation factor 4E binding ; GO:0008190 | inferred from physical interaction with eIF4E1 RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay eukaryotic initiation factor 4E binding ; GO:0008190 | inferred from physical interaction with eIF4E1 inferred from physical interaction with eIF4E4 inferred from physical interaction with eIF4E5 inferred from physical interaction with eIF4E7 inferred from physical interaction with eIF4E3 RNA binding ; GO:0003723 | inferred from direct assay" "mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs spermatid differentiation ; GO:0048515 | inferred from mutant phenotype translation ; GO:0006412 | inferred from direct assay G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from mutant phenotype male germ-line cyst formation ; GO:0048136 | inferred from mutant phenotype spermatocyte division ; GO:0048137 | inferred from genetic interaction with eIF4G2 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity with HGNC:3296,SGD:S000003394 translational initiation ; GO:0006413 | inferred from sequence or structural similarity" eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity "eIF4G, eIF4g, CG10811, Eif4G, p200, deIF4G, eIF-4G, EIF4G, eIF4G1" "IPR003307:W2 domain, IPR003890:MIF4G-like, type 3, IPR003891:Initiation factor eIF-4 gamma, MA3, IPR016024:Armadillo-type fold" CG10811 11-Aug-17 DroID_v2017_08 "Drer\eif4g3a, Drer\eif4g1a, Drer\eif4g1b, Drer\eif4g2b, Drer\eif4g3b, Drer\eif4g2a" "Scer\TIF4631, Scer\TIF4632" Cele\ifg-1 "Xtro\eif4g3, Xtro\LOC100145496" "Mmus\Eif4g3, Mmus\Eif4g2, Mmus\Eif4g1" "Hsap\EIF4G3, Hsap\EIF4G1, Hsap\EIF4G2" lethal DRSC17218 IE 0.876038645 -2.069641687 -2.405192068 -1.40025058 -1.066382831 -0.527779547 FBgn0022265 l(2)k00611 lethal (2) k00611 http://flybase.org/reports/FBgn0022265 - gene - - - l(2)k00611 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000025 acj1 abnormal chemosensory jump 1 http://flybase.org/reports/FBgn0000025 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265212 fs(2)Z2-147 - http://flybase.org/reports/FBgn0265212 gene - - - fs(2)Z2-147 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0010140 l(2)DTS486 lethal (2) DTS486 http://flybase.org/reports/FBgn0010140 - gene - - - "DTS486, l(2)DTS486" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,partially,heat sensitive,female sterile" FBgn0031183 CG14621 - http://flybase.org/reports/FBgn0031183 protein_coding_gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14621, Slc35e1, lincRNA.1043" IPR004853:Sugar phosphate transporter domain CG14621 11-Aug-17 DroID_v2017_08 "Drer\slc35e3, Drer\slc35e4, Drer\slc35e1, Drer\si:ch73-236j9.2" "Scer\YJL193W, Scer\SLY41" - "Xtro\siah3, Xtro\slc35e1" "Mmus\Slc35e4, Mmus\Slc35e2, Mmus\Slc35e1, Mmus\Slc35e3" "Hsap\SLC35E2B, Hsap\SLC35E3, Hsap\SLC35E1, Hsap\SLC35E4, Hsap\SLC35E2" viable FBgn0005025 dumpyoidy dumpyoidy http://flybase.org/reports/FBgn0005025 - gene - - - "dpy, dumpyoidy" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0031971 Sirup Starvation-upregulated protein http://flybase.org/reports/FBgn0031971 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey12, BcDNA:GH18422, dSdhaf4, CG7224, Sirup, Sdhaf4" IPR012875:Protein of unknown function DUF1674 CG7224 11-Aug-17 DroID_v2017_08 Drer\sdhaf4 Scer\SDH8 Cele\W02D3.12 Xtro\sdhaf4 Mmus\Sdhaf4 Hsap\SDHAF4 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0047095 CG33939 - http://flybase.org/reports/FBgn0047095 protein_coding_gene - - - "CR33939, BcDNA:RE54004, CG33939, pncr004:X" - CG33939 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015539 scs special chromatin structure http://flybase.org/reports/FBgn0015539 - insulator - - - "scs, SCS" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028544 CG16884 - http://flybase.org/reports/FBgn0028544 protein_coding_gene - wing disc development ; GO:0035220 | inferred from mutant phenotype - "BG:DS00180.3, CG16884, vajk-3" - CG16884 11-Aug-17 DroID_v2017_08 - - Cele\T26C11.2 - Mmus\Ggn "Hsap\ZNF512B, Hsap\TPRX1, Hsap\GGN" "visible,size defective" "wing vein L3,wing vein L4,anterior crossvein,ectopic,posterior crossvein,wing,posterior,wing cell" FBgn0060837 l(3)S049610 lethal (3) S049610 http://flybase.org/reports/FBgn0060837 gene - - - "0496/10, l(3)S049610" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0032669 CG15155 - http://flybase.org/reports/FBgn0032669 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR013653" - - "CT35055, CG15155" "IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG15155 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-106k19.2, Drer\si:dkey-76k16.5, Drer\si:dkey-76k16.6" - Cele\ZK185.3 - - Hsap\GLYATL3 viable FBgn0050402 CG30402 - http://flybase.org/reports/FBgn0050402 protein_coding_gene - - - CG30402 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030310 PGRP-SA Peptidoglycan recognition protein SA http://flybase.org/reports/FBgn0030310 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | non-traceable author statement peptidoglycan receptor activity ; GO:0016019 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan receptor activity ; GO:0016019 | non-traceable author statement peptidoglycan binding ; GO:0042834 | inferred from direct assay peptidoglycan binding ; GO:0042834 | traceable author statement signaling pattern recognition receptor activity ; GO:0008329 | traceable author statement peptidoglycan binding ; GO:0042834 | non-traceable author statement inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with GNBP1 N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues muramyl dipeptide binding ; GO:0032500 | inferred from direct assay peptidoglycan receptor activity ; GO:0016019 | traceable author statement innate immune response ; GO:0045087 | inferred from electronic annotation with InterPro:IPR017331 defense response to Gram-positive bacterium ; GO:0050830 | inferred from genetic interaction with GNBP1 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria ; GO:0006965 | inferred from mutant phenotype innate immune response ; GO:0045087 | non-traceable author statement peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 response to peptidoglycan ; GO:0032494 | inferred from mutant phenotype regulation of Toll signaling pathway ; GO:0008592 | traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria ; GO:0006965 | traceable author statement immune response ; GO:0006955 | traceable author statement defense response to Gram-positive bacterium ; GO:0050830 | traceable author statement innate immune response ; GO:0045087 | traceable author statement extracellular region ; GO:0005576 | inferred from sequence or structural similarity extracellular region ; GO:0005576 | inferred from direct assay "seml, SEMMELWEIS, CG11709, BcDNA:AT30827, PGRP-SA, Dm PGRP-SA, SA, pgrp-sa" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR017331:Peptidoglycan recognition protein, PGRP-S" CG11709 11-Aug-17 DroID_v2017_08 "Drer\pglyrp6, Drer\pglyrp2, Drer\pglyrp5" - - "Xtro\pglyrp1, Xtro\pglyrp2, Xtro\pglyrp1" "Mmus\Pglyrp3, Mmus\Pglyrp4, Mmus\Pglyrp1, Mmus\Pglyrp2" "Hsap\PGLYRP1, Hsap\PGLYRP3, Hsap\PGLYRP4, Hsap\PGLYRP2" "immune response defective,viable" FBgn0040398 CG14629 - http://flybase.org/reports/FBgn0040398 protein_coding_gene - - - "EG:103E12.2, CG14629" IPR009832:Protein of unknown function DUF1397 CG14629 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033041 Or42a Odorant receptor 42a http://flybase.org/reports/FBgn0033041 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "Or42a, 42a, DOR117, 41E.2, CG17250, Or42A, OR42a" "IPR004117:Olfactory receptor, insect" CG17250 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,viable,fertile" adult olfactory receptor neuron Or42a FBgn0000306 che cherub http://flybase.org/reports/FBgn0000306 - gene - - - che - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,sterile,female sterile" wing FBgn0024631 l(2)k14316 lethal (2) k14316 http://flybase.org/reports/FBgn0024631 - gene - - - "143/16, l(2)k14316" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001278 J Jammed http://flybase.org/reports/FBgn0001278 - gene - - - J - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive,viable,lethal,recessive,reduced" "wing,alula" FBgn0015584 Acp53Ea Accessory gland protein 53Ea http://flybase.org/reports/FBgn0015584 FBgn0063350 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sperm competition ; GO:0046692 | traceable author statement extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "Acp53E, BcDNA:AT09943, CG8622, Acp53Ea, ACP53EA" IPR009392:Drosophila ACP53EA CG8622 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male " male accessory gland

, male accessory gland main cell

" viable FBgn0042165 CG18845 - http://flybase.org/reports/FBgn0042165 protein_coding_gene - - - CG18845 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065461 l(2)SH1372 lethal (2) SH1372 http://flybase.net/reports/FBgn0065461.html gene l(2)SH2 1372 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0022257 l(2)k01006 lethal (2) k01006 http://flybase.org/reports/FBgn0022257 - gene - - - l(2)k01006 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039453 CG6403 - http://flybase.org/reports/FBgn0039453 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG6403 IPR002557:Chitin binding domain CG6403 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037120 CG11247 - http://flybase.org/reports/FBgn0037120 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 regulation of cell cycle ; GO:0051726 | inferred from direct assay - CG11247 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11247 11-Aug-17 DroID_v2017_08 "Drer\zgc:113452, Drer\znf410, Drer\LOC100535506, Drer\si:dkeyp-2e4.8, Drer\zgc:174623, Drer\zgc:171422, Drer\si:dkey-253d23.2" "Scer\ZAP1, Scer\PZF1" "Cele\hinf-1, Cele\C27A12.2, Cele\ztf-23, Cele\sem-4, Cele\eor-1, Cele\fezf-1, Cele\blmp-1, Cele\Y5F2A.4, Cele\lst-5, Cele\Y55F3AM.14, Cele\let-391" Xtro\znf410 "Mmus\Zfp3, Mmus\Zfp639, Mmus\Zfp410, Mmus\Zfp354b, Mmus\Zfp473, Mmus\Zfp354a" "Hsap\ZNF99, Hsap\ZSCAN20, Hsap\ZNF133, Hsap\ZNF639, Hsap\ZNF410, Hsap\ZNF564" "viable,fertile" DRSC26558 K -0.214621344 0.430984818 0.101049218 -0.17493128 0.429641584 -1.529961902 FBgn0039955 CG41099 - http://flybase.org/reports/FBgn0039955 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype epithelial cell morphogenesis ; GO:0003382 | inferred from mutant phenotype vacuole ; GO:0005773 | inferred from direct assay "CG41099, CG17419, CG17416, GM10035, BEST:GM10035" "IPR000210:BTB/POZ domain, IPR000306:FYVE zinc finger, IPR002110:Ankyrin repeat, IPR011011:Zinc finger, FYVE/PHD-type, IPR011333:SKP1/BTB/POZ domain, IPR017455:Zinc finger, FYVE-related, IPR020683:Ankyrin repeat-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG41099 11-Aug-17 DroID_v2017_08 "Drer\ankrd55, Drer\si:ch211-11n16.2, Drer\zak, Drer\ankfy1, Drer\hgs, Drer\ripk3, Drer\ank2a, Drer\dstyk, Drer\ripk4, Drer\zfyve19, Drer\pbk, Drer\ripk2, Drer\ank3b, Drer\LOC405768, Drer\map3k10, Drer\map3k9, Drer\zfyve1, Drer\lrrk2, Drer\mos, Drer\ripk1l, Drer\ank3a, Drer\ank1b, Drer\si:ch211-120p12.3" "Scer\YGL242C, Scer\MGA2, Scer\YCR051W, Scer\VPS27, Scer\SPT23" "Cele\T28D6.4, Cele\F22G12.4, Cele\dhhc-13" "Xtro\lrrk2, Xtro\ank3, Xtro\zfyve19, Xtro\ankk1, Xtro\lrrk1, Xtro\ripk1, Xtro\ank2, Xtro\ank1, Xtro\dstyk, Xtro\hgs, Xtro\mlkl, Xtro\pbk, Xtro\map3k9, Xtro\LOC100490493, Xtro\ankfy1, Xtro\zak, Xtro\zfyve1, Xtro\ripk4, Xtro\map3k7, Xtro\map3k10" "Mmus\Zfyve1, Mmus\Mos, Mmus\Ankrd55, Mmus\Map3k11, Mmus\Ank1, Mmus\BC021891, Mmus\Ank2, Mmus\Map3k9, Mmus\Ripk1, Mmus\Mlkl, Mmus\Pbk, Mmus\Hgs, Mmus\Map3k10, Mmus\Lrrk1, Mmus\Ripk2, Mmus\Zfyve19, Mmus\Ripk4, Mmus\Zak, Mmus\Map3k7, Mmus\Ank3, Mmus\Dstyk, Mmus\Lrrk2, Mmus\Ankfy1, Mmus\Ripk3" "Hsap\PBK, Hsap\ZFYVE19, Hsap\ANK3, Hsap\RIPK4, Hsap\RIPK2, Hsap\ZFYVE1, Hsap\LRRK1, Hsap\MAP3K20, Hsap\ANKRD55, Hsap\HGS, Hsap\LRRK2, Hsap\MAP3K9, Hsap\DSTYK, Hsap\MAP3K11, Hsap\ANK1, Hsap\ANKFY1, Hsap\RIPK3, Hsap\MLKL, Hsap\MOS, Hsap\RIPK1, Hsap\MAP3K21, Hsap\MAP3K10, Hsap\MAP3K7, Hsap\ANK2" viable FBgn0266736 CR45209 - http://flybase.org/reports/FBgn0266736 non_protein_coding_gene - - - CR45209 - CR45209 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262402 mir-311 mir-311 stem loop http://flybase.org/reports/FBgn0262402 miRNA_gene - response to nicotine ; GO:0035094 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cellular response to nitric oxide ; GO:0071732 | inferred from direct assay - "mir-311, miR-311, 311, Dme-miR-311, CR42943, CR33615, dme-mir-311, dme-miR-311, mIR-311" - CR42943 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,partially lethal - majority die" "wing,wing vein,1st posterior cell" FBgn0030786 mRpL22 mitochondrial ribosomal protein L22 http://flybase.org/reports/FBgn0030786 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AA772054 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AA772054 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q3SZX5 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AA772054 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9NWU5 "CG4742, L22, mRpL22" "IPR001063:Ribosomal protein L22/L17, IPR005727:Ribosomal protein L22, bacterial/chloroplast-type" CG4742 11-Aug-17 DroID_v2017_08 Drer\mrpl22 "Scer\RPL17B, Scer\MRPL22, Scer\RPL17A" Cele\mrpl-22 Xtro\mrpl22 Mmus\Mrpl22 Hsap\MRPL22 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC19915 K -0.906735727 -0.25072513 -0.178543384 -0.409460697 -1.94043949 -0.252965782 FBgn0069402 KH3 KH3 http://flybase.org/reports/FBgn0069402 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available KH3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001728 l(1)ESHS49 lethal (1) ESHS49 http://flybase.org/reports/FBgn0001728 - gene - - - l(1)ESHS49 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025814 Mgstl Microsomal glutathione S-transferase-like http://flybase.org/reports/FBgn0025814 "FBgn0031147, FBgn0047002, FBgn0061409" protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from sequence or structural similarity with UniProtKB:P10620 glutathione transferase activity ; GO:0004364 | inferred from sequence or structural similarity with HGNC:7061 - mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:P10620 intracellular membrane-bounded organelle ; GO:0043231 | inferred from sequence or structural similarity with HGNC:7061 lipid particle ; GO:0005811 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | inferred from sequence or structural similarity with UniProtKB:P10620 "Mgst1, CG1742, BcDNA:RH59553, BcDNA:RE10696, Mgstl" "IPR001129:Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein, IPR023352:Membrane associated eicosanoid/glutathione metabolism-like domain" CG1742 11-Aug-17 DroID_v2017_08 "Drer\mgst1.2, Drer\mgst1.1, Drer\ptges" - - "Xtro\ptges, Xtro\mgst1" "Mmus\Mgst1, Mmus\Ptges" "Hsap\PTGES, Hsap\MGST1" "partially lethal - majority die,visible,viable,fertile,short lived" "eye,arista,tarsal segment,macrochaeta,wing,scutellum" FBgn0023083 fray frayed http://flybase.org/reports/FBgn0023083 "FBgn0010922, FBgn0026023" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR024678 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype" "chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype establishment of blood-nerve barrier ; GO:0008065 | inferred from mutant phenotype axon ensheathment ; GO:0008366 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein localization to cell cortex ; GO:0072697 | inferred from genetic interaction with mira, Lkb1 protein phosphorylation ; GO:0006468 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay "STE20-like/SPAK, CG7693, l(3)07551, lag, 4624, fray, Fray, dSTRAD, dOSR1, Dosr1" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR024678:Serine/threonine-protein kinase OSR1/WNK, CCT domain" CG7693 11-Aug-17 DroID_v2017_08 "Drer\oxsr1b, Drer\stk39, Drer\oxsr1a, Drer\wu:fj77h11" Scer\STE20 "Cele\hpo-11, Cele\gck-3" "Xtro\strada, Xtro\stk39, Xtro\stradb" "Mmus\Oxsr1, Mmus\Stk39, Mmus\Stradb, Mmus\Strada" "Hsap\STK39, Hsap\STRADA, Hsap\OXSR1, Hsap\STRADB" " embryonic stage | stage >=15 , embryonic stage | stage >=12 , embryonic stage | early , embryonic stage | stage 17 " " abdominal ventral oblique muscle 6

, larval hindgut

, exit glial cell

, larval midgut

, larval proventriculus

, dorsal neurohemal organ

" "visible,viable,fertile,lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "wing vein,ectopic,wing vein L4,embryonic/first instar larval cuticle,maternal effect,embryonic/larval peripheral nervous system,trichogen cell,posterior wing margin" DRSC16950 K 0.194590866 0.670186911 1.095502173 0.002877787 1.959282807 0.23182972 FBgn0063356 CR30370 - http://flybase.org/reports/FBgn0063356 non_protein_coding_gene - - - "BcDNA:AT05157, CR30370" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040692 CG13938 - http://flybase.org/reports/FBgn0040692 protein_coding_gene - - - CG13938 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039912 CG11260 - http://flybase.org/reports/FBgn0039912 protein_coding_gene - - - CG11260 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019784 l(1)218 lethal (1) 218 http://flybase.org/reports/FBgn0019784 - gene - - - l(1)218 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,recessive" FBgn0038392 CG17631 - http://flybase.org/reports/FBgn0038392 protein_coding_gene - - - CG17631 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033899 CG13016 - http://flybase.org/reports/FBgn0033899 protein_coding_gene - - - CG13016 IPR019397:Uncharacterised protein family TMEM39 CG13016 11-Aug-17 DroID_v2017_08 "Drer\tmem39b, Drer\tmem39a" - Cele\D1007.5 "Xtro\tmem39b, Xtro\tmem39a" "Mmus\Tmem39b, Mmus\Tmem39a" "Hsap\TMEM39A, Hsap\TMEM39B" viable FBgn0001730 l(1)ESHS51 lethal (1) ESHS51 http://flybase.org/reports/FBgn0001730 - gene - - - l(1)ESHS51 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083960 CG34124 - http://flybase.org/reports/FBgn0083960 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium-dependent cell motility ; GO:0060285 | inferred from biological aspect of ancestor with PANTHER:PTN000346980 cellular_component ; GO:0005575 | no biological data available "CG31652, CG34124" "IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG34124 11-Aug-17 DroID_v2017_08 Drer\si:dkey-1f12.3 - - "Xtro\cfap44, Xtro\eml6" "Mmus\Eml5, Mmus\Cfap44, Mmus\Eml6" "Hsap\CFAP44, Hsap\EML6, Hsap\EML5" "viable,fertile" FBgn0065472 l(2)SH1328 lethal (2) SH1328 http://flybase.org/reports/FBgn0065472 gene - - - "l(2)SH1328, l(2)SH2 1328" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031347 CG10869 - http://flybase.org/reports/FBgn0031347 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10869 IPR032013:Protein of unknown function DUF4795 CG10869 11-Aug-17 DroID_v2017_08 - - - - "Mmus\4930562C15Rik, Mmus\Qrich2" "Hsap\QRICH2, Hsap\C16orf96" viable FBgn0041007 CG17541 - http://flybase.org/reports/FBgn0041007 protein_coding_gene - - - CG17541 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260350 GSd302 - http://flybase.org/reports/FBgn0260350 gene - - - GSd302 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0038722 Nup58 Nucleoporin 58kD http://flybase.org/reports/FBgn0038722 protein_coding_gene nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN001412288 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with UniProtKB:P70581 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN001412288 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN001412288 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype nucleocytoplasmic transport ; GO:0006913 | inferred from sequence or structural similarity with UniProtKB:P70581 nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN001412288 nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with UniProtKB:P70581 "CG7360, Nup58, Dm NUP58, RE52572p" "IPR024945:Spt5 C-terminal domain, IPR024882:Nucleoporin p58/p45" CG7360 11-Aug-17 DroID_v2017_08 "Drer\nup58, Drer\nup98, Drer\nup62l" "Scer\NUP100, Scer\NSP1, Scer\NUP49, Scer\NUP145, Scer\NUP116" "Cele\npp-11, Cele\npp-10" Xtro\nup58 "Mmus\Nup98, Mmus\Nup62, Mmus\Nup62cl, Mmus\Nupl1" "Hsap\NUP98, Hsap\NUP58, Hsap\NUP62" "sterile,partially lethal,viable" FBgn0037985 ssp5 short spindle 5 http://flybase.org/reports/FBgn0037985 protein_coding_gene - - - "anon-WO0140519.127, ssp5, CG14735, Ssp5, Tes59" "IPR031936:Domain of unknown function DUF4771, IPR031935:Domain of unknown function DUF4770" CG14735 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036490 CG6888 - http://flybase.org/reports/FBgn0036490 protein_coding_gene thioredoxin peroxidase activity ; GO:0008379 | inferred from sequence or structural similarity with HGNC:9352 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 hydrogen peroxide catabolic process ; GO:0042744 | inferred from sequence or structural similarity with HGNC:9352 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:9352 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:9352 "BcDNA:AT16346, CG6888, 6888" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR024706:Peroxiredoxin, AhpC-type, IPR013766:Thioredoxin domain" CG6888 11-Aug-17 DroID_v2017_08 "Drer\prdx4, Drer\prdx3, Drer\prdx6, Drer\prdx1, Drer\prdx2" "Scer\PRX1, Scer\TSA1, Scer\TSA2" "Cele\prdx-2, Cele\prdx-6, Cele\prdx-3" "Xtro\prdx2, Xtro\prdx3, Xtro\prdx1, Xtro\prdx4" "Mmus\Prdx3, Mmus\Prdx1, Mmus\Prdx2, Mmus\Prdx6, Mmus\Prdx4" "Hsap\PRDX1, Hsap\PRDX4, Hsap\PRDX6, Hsap\PRDX3, Hsap\PRDX2" "viable,fertile" FBgn0005601 yemG2.8 yema gene 2.8 http://flybase.org/reports/FBgn0005601 FBgn0004042 gene - - - "yG2.8/2.6, yG2.8, yG2.6, yT2.8, yT2.6, yemG2.8" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && oogenesis stage , embryonic stage | stage <=8 , embryonic stage | stage <6 , embryonic stage | stage <= 8 " " ovary

, organism

" FBgn0027560 Tps1 Trehalose-6-phosphate synthase 1 http://flybase.org/reports/FBgn0027560 "FBgn0001908, FBgn0022028" protein_coding_gene trehalose-phosphatase activity ; GO:0004805 | inferred from direct assay trehalose metabolism in response to stress ; GO:0070413 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype trehalose biosynthetic process ; GO:0005992 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 lipid particle ; GO:0005811 | inferred from direct assay "BcDNA:GH08860, tps1, TreS, CG4104, dtps1, TPS, jf5, l(2)k08903, l(2)jf5, l(2)jf4, l(2)24Ea, Tps1, CG4104 PA, dTps1, 19920676" "IPR001830:Glycosyl transferase, family 20, IPR003337:Trehalose-phosphatase, IPR006379:HAD-superfamily hydrolase, subfamily IIB, IPR023214:HAD-like domain" CG4104 11-Aug-17 DroID_v2017_08 - "Scer\TPS2, Scer\TPS3, Scer\TSL1, Scer\TPS1" "Cele\tps-1, Cele\tps-2, Cele\gob-1" - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" "eye,ommatidium" FBgn0002995 om ommatidia http://flybase.org/reports/FBgn0002995 - gene - - - om - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,ommatidium" FBgn0030799 CG4872 - http://flybase.org/reports/FBgn0030799 protein_coding_gene "transcription corepressor activity ; GO:0003714 | inferred from sequence or structural similarity with HGNC:2418 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor ; GO:0016639 | inferred from biological aspect of ancestor with PANTHER:PTN000352164 hormone binding ; GO:0042562 | inferred from biological aspect of ancestor with PANTHER:PTN001013561" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:2418 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:2418 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000352164 CG4872 "IPR003462:Ornithine cyclodeaminase/mu-crystallin, IPR016040:NAD(P)-binding domain, IPR023401:Ornithine cyclodeaminase, N-terminal" CG4872 11-Aug-17 DroID_v2017_08 Drer\crym Scer\YGL159W - Xtro\crym Mmus\Crym Hsap\CRYM FBgn0015857 anon-14Aa anon-14Aa http://flybase.org/reports/FBgn0015857 - gene - - - "t6, anon-14Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005704 l(1)TK107 lethal (1) TK107 http://flybase.org/reports/FBgn0005704 - gene - - - "l107, l(1)TK107" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0019701 l(2)42Bb lethal (2) 42Bb http://flybase.org/reports/FBgn0019701 - gene - - - "l(2)6G1, 6G1, l(2)42Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045473 Gr85a Gustatory receptor 85a http://flybase.org/reports/FBgn0045473 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "CG31405, Gr85a" IPR013604:7TM chemoreceptor CG31405 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267426 CR45779 - http://flybase.org/reports/FBgn0267426 pseudogene_attribute - - - "CR45779, Mst77Y" - CR45779 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010849 l(3)04837 lethal (3) 04837 http://flybase.org/reports/FBgn0010849 - gene molecular_function ; GO:0003674 | no biological data available segmentation ; GO:0035282 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(3)04837 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect,poor" "embryonic/first instar larval cuticle,maternal effect,segment" FBgn0031020 Naa15-16 N(alpha)-acetyltransferase 15/16 http://flybase.org/reports/FBgn0031020 protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000511059 N-terminal peptidyl-methionine acetylation ; GO:0017196 | inferred from biological aspect of ancestor with PANTHER:PTN000511059 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic spindle ; GO:0072686 | inferred from direct assay NatA complex ; GO:0031415 | inferred from biological aspect of ancestor with PANTHER:PTN000511117 NatA complex ; GO:0031415 | inferred from direct assay protein acetyltransferase complex ; GO:0031248 | inferred from physical interaction with UniProtKB:Q9NHD5 "CG12202, dNat1, l(1)G0311, Nat1, Naa15, dNaa15, Naa15-16, Naa15/16, NAA15-16" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR021183:N-terminal acetyltransferase A, auxiliary subunit" CG12202 11-Aug-17 DroID_v2017_08 "Drer\naa15a, Drer\naa15b" Scer\NAT1 Cele\hpo-29 "Xtro\naa15, Xtro\naa16" "Mmus\Naa15, Mmus\Naa16" "Hsap\NAA16, Hsap\NAA15" "viable,fertile,lethal,recessive,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC19440 IE 1.118109638 2.123228374 1.101715375 1.73970854 0.055528706 -0.511190298 FBgn0034617 Panx Panoramix http://flybase.org/reports/FBgn0034617 protein_coding_gene molecular_function ; GO:0003674 | no biological data available piRNA biosynthetic process ; GO:1990511 | inferred from direct assay positive regulation of methylation-dependent chromatin silencing ; GO:0090309 | inferred from direct assay inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG9754, Panx, pan, Silencio" - CG9754 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile" FBgn0046839 l(3)A4-4L1 lethal (3) A4-4L1 http://flybase.org/reports/FBgn0046839 gene - - - l(3)A4-4L1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263845 CR43706 - http://flybase.org/reports/FBgn0263845 non_protein_coding_gene - - - CR43706 - CR43706 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265921 CR44710 - http://flybase.org/reports/FBgn0265921 non_protein_coding_gene - - - "CR44710, lincRNA.1029" - CR44710 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262580 CG43120 - http://flybase.org/reports/FBgn0262580 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43120 "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG43120 11-Aug-17 DroID_v2017_08 "Drer\btbd6b, Drer\btbd17b, Drer\btbd6a, Drer\btbd2, Drer\btbd3a, Drer\btbd3b" - - "Xtro\btbd1, Xtro\btbd2, Xtro\btbd3, Xtro\btbd6" "Mmus\Btbd6, Mmus\Btbd17, Mmus\Btbd1, Mmus\Btbd2, Mmus\Btbd3" "Hsap\BTBD3, Hsap\BTBD1, Hsap\BTBD2, Hsap\BTBD17, Hsap\BTBD6" FBgn0000195 blc blocked http://flybase.org/reports/FBgn0000195 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available blc - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male sterile" "germline cell,female" FBgn0000687 flrdJ flight reduced J http://flybase.org/reports/FBgn0000687 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "flrdI, flrdJ" - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0022935 D19A D19A http://flybase.org/reports/FBgn0022935 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 "CG10269, D19A, d19a" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10269 11-Aug-17 DroID_v2017_08 "Drer\zgc:174268, Drer\znf770, Drer\znf1004, Drer\znf668, Drer\znf990, Drer\si:dkey-33c14.6, Drer\znf341, Drer\zgc:162948" Scer\PZF1 "Cele\eor-1, Cele\ZK546.5, Cele\Y55F3AM.14, Cele\Y37F4.6, Cele\Y48G8AL.10, Cele\hinf-1, Cele\hbl-1, Cele\sem-4" "Xtro\hic1, Xtro\znf668" "Mmus\Zfp672, Mmus\Plagl1, Mmus\Zfp341, Mmus\Zfp668" "Hsap\ZNF317, Hsap\ZNF555, Hsap\ZNF782, Hsap\ZNF284, Hsap\ZNF341, Hsap\ZNF221, Hsap\ZNF668, Hsap\ZNF43" viable DRSC11133 IEK -1.89875976 -2.851653906 -2.516288756 -4.184940303 0.494635396 1.650365893 FBgn0001048 fs(3)HO231 female sterile (3) HO231 http://flybase.org/reports/FBgn0001048 - gene - - - "fs(3)231A, fs(3)HO231" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033221 CG12825 - http://flybase.org/reports/FBgn0033221 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from sequence model "CG12825, dmCG12825" - CG12825 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262436 mir-310 mir-310 stem loop http://flybase.org/reports/FBgn0262436 miRNA_gene - response to nicotine ; GO:0035094 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cellular response to nitric oxide ; GO:0071732 | inferred from direct assay compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype - "mir-310, miR-310, Dme-miR-310, CR42995, Mir-310, CR33614, dme-mir-310, miR310, mIR-310" - CR42995 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal - all die before end of larval stage,some die during larval stage,lethal,partially lethal - majority die" "wing hair,wing" FBgn0039505 CG5934 - http://flybase.org/reports/FBgn0039505 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG5934 IPR019357:Predicted coiled-coil protein (DUF2205) CG5934 11-Aug-17 DroID_v2017_08 "Drer\scocb, Drer\scoca" - Cele\unc-69 Xtro\scoc Mmus\Scoc Hsap\SCOC viable FBgn0030592 CG9514 - http://flybase.org/reports/FBgn0030592 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG9514, Dm GMCdelta1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR023753:FAD/NAD(P)-binding domain" CG9514 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable DRSC30059 K 0.878152916 0.267693627 0.167029725 0.592564886 0.343996625 -1.700268826 FBgn0036640 nxf2 nuclear RNA export factor 2 http://flybase.org/reports/FBgn0036640 protein_coding_gene - poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from biological aspect of ancestor with PANTHER:PTN000070434 nucleoplasm ; GO:0005654 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "NXF2, CG4118, nxf2" "IPR018222:Nuclear transport factor 2, eukaryote, IPR005637:TAP C-terminal (TAP-C) domain, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR032710:NTF2-like domain, IPR030217:Nuclear RNA export factor, IPR009060:UBA-like" CG4118 11-Aug-17 DroID_v2017_08 "Drer\zgc:153681, Drer\nxf1" Scer\MEX67 "Cele\nxf-1, Cele\nxf-2" Xtro\nxf1 "Mmus\Nxf1, Mmus\Tmem223, Mmus\Nxf7, Mmus\Nxf2, Mmus\Nxf3" "Hsap\NXF1, Hsap\NXF2, Hsap\NXF3, Hsap\NXF2B, Hsap\NXF5" "female sterile,female fertile" DRSC10403 I -1.547157048 0.790849092 -0.046858054 0.276373273 -1.105280854 -0.112959855 FBgn0003479 spn-A spindle A http://flybase.org/reports/FBgn0003479 FBgn0011700 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR020587, InterPro:IPR020588 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W157 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from sequence or structural similarity with HGNC:9817 endodeoxyribonuclease activity ; GO:0004520 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 DNA-dependent ATPase activity ; GO:0008094 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 four-way junction DNA binding ; GO:0000400 | inferred from biological aspect of ancestor with PANTHER:PTN001415033" "mitotic recombination-dependent replication fork processing ; GO:1990426 | inferred from electronic annotation with InterPro:IPR011941 oogenesis ; GO:0048477 | traceable author statement polarity specification of dorsal/ventral axis ; GO:0009951 | inferred from mutant phenotype oocyte fate determination ; GO:0030716 | inferred from mutant phenotype double-strand break repair via synthesis-dependent strand annealing ; GO:0045003 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from biological aspect of ancestor with PANTHER:PTN001489025 regulation of double-strand break repair via homologous recombination ; GO:0010569 | inferred from mutant phenotype DNA recombination ; GO:0006310 | inferred from sequence or structural similarity with HGNC:9817 polarity specification of anterior/posterior axis ; GO:0009949 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | traceable author statement karyosome formation ; GO:0030717 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from sequence or structural similarity with HGNC:9817 germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with mus301 DNA recombinase assembly ; GO:0000730 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 response to ionizing radiation ; GO:0010212 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 mitotic recombination ; GO:0006312 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 oogenesis ; GO:0048477 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype chromosome organization involved in meiotic cell cycle ; GO:0070192 | inferred from biological aspect of ancestor with PANTHER:PTN001489025 DNA repair ; GO:0006281 | inferred from genetic interaction with Blm, mus81 female meiotic division ; GO:0007143 | inferred from mutant phenotype strand invasion ; GO:0042148 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 double-strand break repair ; GO:0006302 | inferred from mutant phenotype response to caffeine ; GO:0031000 | inferred from genetic interaction with MAGE" condensed nuclear chromosome ; GO:0000794 | inferred from biological aspect of ancestor with PANTHER:PTN001489025 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001489025 "DmRad51, spnA, dmRAD51, Rad51, Dm Rad51, D37788, DmRAD51, RAD51, CG7948, DMR, Dmrad51, DMR/DroRAD51, RA51, Rad51dm, DMR1, spn-A, rad51, Spn-A, RA51_DROME, dmrad51, SpnA" "IPR003593:AAA+ ATPase domain, IPR010995:DNA repair Rad51/transcription factor NusA, alpha-helical, IPR011941:DNA recombination/repair protein Rad51, IPR013632:DNA recombination and repair protein Rad51-like, C-terminal, IPR016467:DNA recombination and repair protein, RecA-like, IPR020587:DNA recombination and repair protein RecA, monomer-monomer interface, IPR020588:DNA recombination and repair protein RecA-like, ATP-binding domain, IPR033925:Rad51/DMC1/RadA, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7948 11-Aug-17 DroID_v2017_08 "Drer\rad51, Drer\rad51b, Drer\dmc1, Drer\rad51d" "Scer\DMC1, Scer\RAD51" Cele\rad-51 "Xtro\rad51, Xtro\rad51d" "Mmus\Dmc1, Mmus\Rad51, Mmus\Rad51d, Mmus\Rad51b" "Hsap\DMC1, Hsap\RAD51D, Hsap\RAD51, Hsap\RAD51B" "viable,lethal,maternal effect,semi-fertile,radiation sensitive,dominant,DNA repair defective,meiotic cell cycle defective,female,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal appendage,germline clone,chorion | dorsal | germline clone,egg,presumptive oocyte,karyosome,chorion,maternal effect,synaptonemal complexX3F),chorion | dorsalX3F),dorsal,oocyte,nurse cell,egg chamber,synaptonemal complex,germline cyst" DRSC16812 K -0.18460639 0.050961495 -0.157866144 0.030878465 2.326013271 0.759214734 FBgn0040905 CG15578 - http://flybase.org/reports/FBgn0040905 protein_coding_gene - - - CG15578 - CG15578 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010343 HIS-C Histone complex http://flybase.org/reports/FBgn0010343 - protein_coding_gene - - - "his, HIS-C, histone, His-C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024712 anon-57Co anon-57Co http://flybase.org/reports/FBgn0024712 - gene - - - anon-57Co - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060778 l(3)S060711a lethal (3) S060711a http://flybase.org/reports/FBgn0060778 gene - - - "0607/11, l(3)S060711a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0267478 CR45828 - http://flybase.org/reports/FBgn0267478 non_protein_coding_gene - - - CR45828 - CR45828 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038750 CG4465 - http://flybase.org/reports/FBgn0038750 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG4465 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG4465 11-Aug-17 DroID_v2017_08 "Drer\oatx, Drer\LOC101884074, Drer\slc22a13, Drer\slc22a21, Drer\zgc:175176, Drer\slc22a5, Drer\slc22a4, Drer\slc22a6l, Drer\slc22a2, Drer\sv2, Drer\LOC100334012, Drer\slc22a7b.1, Drer\zmp:0000001102, Drer\slc22a7b.2, Drer\slc22a7b.3" "Scer\QDR1, Scer\YHK8, Scer\DTR1, Scer\TPO2, Scer\TPO1, Scer\FLR1, Scer\TPO3, Scer\QDR3, Scer\AQR1, Scer\QDR2" "Cele\T22F7.1, Cele\oct-2, Cele\K09E9.1" Xtro\slc22a6 "Mmus\Slc22a3, Mmus\Slc22a27, Mmus\Slc22a28, Mmus\Slc22a29, Mmus\Slc22a1, Mmus\Svop, Mmus\Slc22a7, Mmus\Slc22a4, Mmus\Slc22a2, Mmus\Slc22a16, Mmus\Slc22a23, Mmus\Slc22a30, Mmus\Slc22a14, Mmus\Slc22a26, Mmus\Sv2c, Mmus\Slc22a19, Mmus\Slc22a6, Mmus\Slc22a20, Mmus\Slc22a22, Mmus\Slc22a8" "Hsap\SLC22A7, Hsap\SV2C, Hsap\SV2B, Hsap\SLC22A12, Hsap\SLC22A3, Hsap\SLC22A1, Hsap\SLC22A11, Hsap\SVOP, Hsap\SLC22A2, Hsap\SLC22A6, Hsap\SLC22A25, Hsap\SLC22A9, Hsap\SLC22A10, Hsap\SLC22A24, Hsap\SLC22A23, Hsap\SLC22A8" "viable,fertile" DRSC15584 E -0.01569009 -0.207640764 -1.832399723 -0.003269499 0.456789135 0.528808937 FBgn0046645 anon-38D.21 anon-38D.21 http://flybase.org/reports/FBgn0046645 gene - - - "38D.21, anon-38D.21" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263898 A44 - http://flybase.org/reports/FBgn0263898 gene - - - A44 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0065775 l(2)SH0454 lethal (2) SH0454 http://flybase.org/reports/FBgn0065775 gene - - - "l(2)SH0454, l(2)SH2 0454" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082954 snoRNA:Psi28S-3571 snoRNA:Psi28S-3571 http://flybase.org/reports/FBgn0082954 snoRNA_gene - - - "snoRNA:Psi28S-3571, psi28s-3571, Psi 28S-3571, CR34611, chr3R:1423362..1423500" - CR34611 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053194 CheA29a Chemosensory protein A 29a http://flybase.org/reports/FBgn0053194 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from expression pattern detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model "CG33194, CheA29a" - CG33194 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male " prothoracic tarsal segment

, prothoracic tarsal segment 3

, prothoracic tarsal segment 2

, head

, prothoracic tarsal segment 1

, prothoracic tarsal segment 4

" "viable,fertile" DRSC21486 K -0.328872632 0.196732457 0.688702037 0.631062025 -1.575566016 -1.801877171 FBgn0002308 l(3)84Ff lethal (3) 84Ff http://flybase.org/reports/FBgn0002308 - gene - - - "l(3)EfK3, l(3)84Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039333 CG11917 - http://flybase.org/reports/FBgn0039333 protein_coding_gene - - - CG11917 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060604 l(3)S091104 lethal (3) S091104 http://flybase.org/reports/FBgn0060604 gene - - - "0911/04, l(3)S091104" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065127 l(3)SH138 lethal (3) SH138 http://flybase.org/reports/FBgn0065127 gene - - - "l(3)SH138, l(2)SH3 138" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001024 fs(3)A15 female sterile (3) A15 http://flybase.org/reports/FBgn0001024 - gene - - - fs(3)A15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,mitotic cell cycle defective" "female reproductive system,spindle" FBgn0265646 CR44453 - http://flybase.org/reports/FBgn0265646 non_protein_coding_gene - - - "lincRNA.293, CR44453" - CR44453 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066084 RpL41 Ribosomal protein L41 http://flybase.org/reports/FBgn0066084 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000002343 structural constituent of ribosome ; GO:0003735 | non-traceable author statement translation ; GO:0006412 | non-traceable author statement cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred from sequence or structural similarity with SGD:S000002343 nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic large ribosomal subunit ; GO:0022625 | inferred from sequence or structural similarity with SGD:S000002343 "pncr005:2R, CG30425, L41, BcDNA:RE63504, BEST:LP07070, BcDNA:LP07070, CR30425, RpL41, Rpl41" IPR007836:Ribosomal protein L41 CG30425 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040650 CG15456 - http://flybase.org/reports/FBgn0040650 protein_coding_gene - - - CG15456 "IPR011893:Selenoprotein, Rdx type, IPR012336:Thioredoxin-like fold" CG15456 11-Aug-17 DroID_v2017_08 "Drer\sepw2a, Drer\sepw2b, Drer\sepw1" - Cele\F28H7.4 Xtro\mien1 "Mmus\Mien1, Mmus\Selenow" "Hsap\MIEN1, Hsap\SELENOW" viable FBgn0266274 T:SS-trypsin Signal sequence of trypsin http://flybase.org/reports/FBgn0266274 engineered_foreign_region - - - T:SS-trypsin - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036440 CG17177 - http://flybase.org/reports/FBgn0036440 protein_coding_gene - - - CG17177 - CG17177 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060411 l(3)S130204b lethal (3) S130204b http://flybase.org/reports/FBgn0060411 gene - - - "1302/04, l(3)S130204b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003341 scrp scarp http://flybase.org/reports/FBgn0003341 - gene - - - scrp - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,heat sensitive" FBgn0267182 CR45622 - http://flybase.org/reports/FBgn0267182 non_protein_coding_gene - - - CR45622 - CR45622 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015449 l(1)9Fi lethal (1) 9Fi http://flybase.org/reports/FBgn0015449 - gene - - - l(1)9Fi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0034422 CG7137 - http://flybase.org/reports/FBgn0034422 protein_coding_gene methylated histone binding ; GO:0035064 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 methylated histone binding ; GO:0035064 | inferred from sequence or structural similarity with UniProtKB:O43159 S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from biological aspect of ancestor with PANTHER:PTN000300315 chromatin silencing at rDNA ; GO:0000183 | inferred from sequence or structural similarity with UniProtKB:O43159 cellular response to glucose starvation ; GO:0042149 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 chromatin silencing at rDNA ; GO:0000183 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 regulation of transcription by glucose ; GO:0046015 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 chromatin silencing complex ; GO:0005677 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000300315 rDNA heterochromatin ; GO:0033553 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:O43159 rDNA heterochromatin ; GO:0033553 | inferred from sequence or structural similarity with UniProtKB:O43159 chromatin silencing complex ; GO:0005677 | inferred from sequence or structural similarity with UniProtKB:O43159 CG7137 "IPR007823:Ribosomal RNA processing protein 8, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG7137 11-Aug-17 DroID_v2017_08 Drer\si:ch211-149e23.3 Scer\RRP8 Cele\T07A9.8 - Mmus\Rrp8 Hsap\RRP8 "viable,visible" trichogen cell FBgn0037356 CG12170 - http://flybase.org/reports/FBgn0037356 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR017568" fatty acid biosynthetic process ; GO:0006633 | inferred from electronic annotation with InterPro:IPR017568 - "anon-WO0118547.367, CG12170" "IPR018201:Beta-ketoacyl synthase, active site, IPR014030:Beta-ketoacyl synthase, N-terminal, IPR014031:Beta-ketoacyl synthase, C-terminal, IPR016039:Thiolase-like, IPR017568:3-oxoacyl-[acyl-carrier-protein] synthase 2, IPR020841:Polyketide synthase, beta-ketoacyl synthase domain" CG12170 11-Aug-17 DroID_v2017_08 Drer\oxsm Scer\CEM1 Cele\F10G8.9 Xtro\oxsm Mmus\Oxsm Hsap\OXSM viable FBgn0264898 CR44089 - http://flybase.org/reports/FBgn0264898 non_protein_coding_gene - - - CR44089 - CR44089 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033734 CG8520 - http://flybase.org/reports/FBgn0033734 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR005654 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG8520, FBgn 33734" "IPR005654:ATPase, AFG1-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8520 11-Aug-17 DroID_v2017_08 "Drer\lace1b, Drer\lace1a" Scer\AFG1 Cele\C30F12.2 Xtro\lace1 Mmus\Lace1 Hsap\LACE1 "viable,fertile" FBgn0053470 CG33470 - http://flybase.org/reports/FBgn0053470 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33470 - CG33470 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033861 CG12464 - http://flybase.org/reports/FBgn0033861 protein_coding_gene - - mitochondrial respiratory chain complex I ; GO:0005747 | inferred from electronic annotation with InterPro:IPR026193 CG12464 IPR026193:NADH-ubiquinone oxidoreductase flavoprotein 3 CG12464 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025576 M285 M285 http://flybase.org/reports/FBgn0025576 - gene molecular_function ; GO:0003674 | no biological data available Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N nervous system development ; GO:0007399 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from genetic interaction with N imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available M285 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0084025 CG41464 - http://flybase.org/reports/FBgn0084025 protein_coding_gene - - - CG41464 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044506 BS\RTase BS element RTase http://flybase.org/reports/FBgn0044506 transposable_element_gene - - cellular_component ; GO:0005575 | no biological data available "RT, Bs ORF2, BS\RTase, RTase" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036838 CG3808 - http://flybase.org/reports/FBgn0036838 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 RNA methyltransferase activity ; GO:0008173 | inferred from electronic annotation with InterPro:IPR010280 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR010280 - "cg3808, CG3808" "IPR000504:RNA recognition motif domain, IPR030391:RNA methyltransferase TrmA, conserved site, IPR030390:RNA methyltransferase TrmA, active site, IPR010280:(Uracil-5)-methyltransferase family, IPR034262:TRMT2A, RNA recognition motif, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG3808 11-Aug-17 DroID_v2017_08 "Drer\trmt2b, Drer\trmt2a" Scer\TRM2 Cele\H24K24.4 "Xtro\trmt2b, Xtro\trmt2a" "Mmus\Trmt2a, Mmus\Trmt2b" "Hsap\TRMT2A, Hsap\TRMT2B" "viable,fertile" FBgn0058257 CR40257 - http://flybase.org/reports/FBgn0058257 non_protein_coding_gene - - - CR40257 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065817 l(2)SH0377 lethal (2) SH0377 http://flybase.org/reports/FBgn0065817 gene - - - "l(2)SH0377, l(2)SH2 0377" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052791 DIP-alpha Dpr-interacting protein alpha http://flybase.org/reports/FBgn0052791 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern neuron projection membrane ; GO:0032589 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG32791, CG13020, CG13019, 32791, DIP-alpha" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG32791 11-Aug-17 DroID_v2017_08 "Drer\mxra8b, Drer\zgc:110372, Drer\lsamp, Drer\si:zfos-1011f11.1, Drer\gpa33, Drer\vsig8a, Drer\si:dkey-65b12.12, Drer\mxra8a, Drer\cxcr3.1, Drer\si:ch211-9d9.7, Drer\si:ch211-215e19.3, Drer\f11r.1, Drer\jam3b, Drer\vsig8b, Drer\f11r.2, Drer\pigrl4.2, Drer\ntm, Drer\jam3a, Drer\jam2a, Drer\LOC100151468, Drer\si:dkey-250k15.10, Drer\negr1, Drer\opcml, Drer\igsf11, Drer\cxadr, Drer\jam2b, Drer\esamb, Drer\esama, Drer\zgc:153073" - "Cele\rig-5, Cele\zig-4" "Xtro\ntm, Xtro\negr1, Xtro\lsamp" "Mmus\Esam, Mmus\Vsig8, Mmus\Igsf11, Mmus\Iglon5, Mmus\Jam3, Mmus\Vsig2, Mmus\Vsir, Mmus\Opcml, Mmus\F11r, Mmus\Clmp, Mmus\Negr1, Mmus\Ntm, Mmus\Mxra8, Mmus\Gm1123, Mmus\Hepacam2, Mmus\Jam2, Mmus\Vsig1, Mmus\Igsf5, Mmus\Lsamp, Mmus\Gpa33, Mmus\Cxadr" "Hsap\GPA33, Hsap\CLMP, Hsap\NEGR1, Hsap\IGSF11, Hsap\JAM3, Hsap\IGLON5, Hsap\F11R, Hsap\CXADR, Hsap\MXRA8, Hsap\VSIG1, Hsap\VSIG8, Hsap\OPCML, Hsap\NTM, Hsap\C1orf204, Hsap\LSAMP, Hsap\VSIG2, Hsap\JAM2, Hsap\ESAM, Hsap\C10orf54, Hsap\IGSF5" "visible,partially lethal - majority die,some die during pupal stage,lethal" "chaeta,supernumerary,trichogen cell" FBgn0060840 l(3)S049508b lethal (3) S049508b http://flybase.org/reports/FBgn0060840 gene - - - "0495/08, l(3)S049508b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0050371 CG30371 - http://flybase.org/reports/FBgn0050371 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP80, CG2280, CG30371" "IPR000859:CUB domain, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG30371 11-Aug-17 DroID_v2017_08 Drer\f10 - "Cele\F25E5.3, Cele\svh-1, Cele\try-5, Cele\try-9, Cele\T21E12.3" - "Mmus\Tmprss7, Mmus\Tmprss6, Mmus\St14" "Hsap\TMPRSS6, Hsap\TMPRSS7, Hsap\F10, Hsap\ST14" "viable,visible" "antenna,leg,ectopic" FBgn0025472 qkr58E-5 quaking related 58E-5 http://flybase.org/reports/FBgn0025472 - gene - - - "qrk58E-5, qkr58E-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267739 CR46070 - http://flybase.org/reports/FBgn0267739 non_protein_coding_gene - - - "CR46070, Mgn3671" - CR46070 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051754 His-Psi:CR31754 His-Psi:CR31754 http://flybase.org/reports/FBgn0051754 pseudogene_attribute - - - "CR31754, His-Psi:CR31754" - CR31754 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22051 IE 1.765175641 -3.517577589 -1.389565049 -5.118172072 0.626504918 0.964516608 FBgn0263841 CG43702 - http://flybase.org/reports/FBgn0263841 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43702 - CG43702 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029895 CG14441 - http://flybase.org/reports/FBgn0029895 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG14441 "IPR012934:Zinc finger, AD-type, IPR019400:Peptidase C65, otubain, IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG14441 11-Aug-17 DroID_v2017_08 Drer\srcap Scer\SWR1 Cele\ssl-1 - Mmus\Srcap Hsap\SRCAP "viable,fertile" FBgn0037005 CG5078 - http://flybase.org/reports/FBgn0037005 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701" CG5078 "IPR001958:Tetracycline resistance protein TetA/multidrug resistance protein MdtG, IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG5078 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-5g14.1, Drer\hiat1b, Drer\si:ch211-262i1.4, Drer\hiat1a, Drer\LOC557306, Drer\zgc:174356, Drer\slc46a3, Drer\si:ch211-87m7.2" Scer\YJL163C "Cele\T25D3.4, Cele\Y71G12B.25" "Xtro\mfsd14a, Xtro\mfsd14b" "Mmus\Slc46a3, Mmus\Mfsd14b, Mmus\Slc46a1, Mmus\Mfsd14a" "Hsap\MFSD14A, Hsap\MFSD14B, Hsap\SLC46A1, Hsap\SLC46A3" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0000683 flrdF flight reduced F http://flybase.org/reports/FBgn0000683 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdF - - 11-Aug-17 DroID_v2017_08 - - - - - - "jumping defective,flightless" FBgn0065115 l(3)SH160 lethal (3) SH160 http://flybase.org/reports/FBgn0065115 gene - - - "l(3)SH160, l(2)SH3 160" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065493 l(2)SH1228 lethal (2) SH1228 http://flybase.org/reports/FBgn0065493 gene - - - "l(2)SH1228, l(2)SH2 1228" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267802 CR46127 - http://flybase.org/reports/FBgn0267802 non_protein_coding_gene - - - CR46127 - CR46127 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029789 PGAP1 Post-GPI attachment to proteins 1 http://flybase.org/reports/FBgn0029789 protein_coding_gene phosphoric ester hydrolase activity ; GO:0042578 | inferred from sequence or structural similarity with UniProtKB:Q765A7 nuclease activity ; GO:0004518 | inferred from sequence or structural similarity with UniProtKB:Q765A7 myo-inositol transport ; GO:0015798 | inferred from sequence or structural similarity with UniProtKB:Q765A7 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q765A7 "CG3160, PGAP1" "IPR012908:GPI inositol-deacylase PGAP1-like, IPR029058:Alpha/Beta hydrolase fold" CG3160 11-Aug-17 DroID_v2017_08 Drer\pgap1 Scer\BST1 "Cele\her-1, Cele\T19B10.8, Cele\lips-9, Cele\nhr-49" - "Mmus\Pgap1, Mmus\Epas1" "Hsap\PGAP1, Hsap\C2orf66" "viable,body color defective" mesothoracic tergum FBgn0031187 Usp2 Ubiquitin specific protease 2 http://flybase.org/reports/FBgn0031187 protein_coding_gene Lys48-specific deubiquitinase activity ; GO:1990380 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with imd thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:12631 proteasome binding ; GO:0070628 | inferred from physical interaction with Rpt6 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype negative regulation of defense response to bacterium ; GO:1900425 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from mutant phenotype protein K48-linked deubiquitination ; GO:0071108 | inferred from direct assay protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:12631 negative regulation of antimicrobial peptide production ; GO:0002785 | inferred from mutant phenotype positive regulation of proteasomal protein catabolic process ; GO:1901800 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG14619, Usp2, Q9VR54, dUsp2" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG14619 11-Aug-17 DroID_v2017_08 "Drer\usp4, Drer\usp43b, Drer\usp8, Drer\usp2b, Drer\usp21, Drer\usp32, Drer\usp11, Drer\usp2a" "Scer\UBP5, Scer\UBP7, Scer\UBP11, Scer\DOA4, Scer\UBP12, Scer\UBP8" "Cele\F07A11.4, Cele\usp-3, Cele\H34C03.2, Cele\usp-33, Cele\cyk-3, Cele\usp-50" "Xtro\usp21, Xtro\usp15, Xtro\usp8, Xtro\usp37, Xtro\usp2" "Mmus\Usp15, Mmus\Usp4, Mmus\Usp26, Mmus\Usp27x, Mmus\Usp43, Mmus\Usp22, Mmus\Usp2, Mmus\Usp11, Mmus\Usp8, Mmus\Usp3, Mmus\Usp32, Mmus\Usp37, Mmus\Usp29, Mmus\Usp21, Mmus\Usp50" "Hsap\USP4, Hsap\USP50, Hsap\USP37, Hsap\USP11, Hsap\USP3, Hsap\USP2, Hsap\USP21, Hsap\USP10, Hsap\USP8, Hsap\USP27X, Hsap\USP22, Hsap\USP43, Hsap\USP29, Hsap\USP32, Hsap\USP26" "lethal,recessive,body color defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,viable,locomotor behavior defective,short lived" "mesothoracic tergum,prepupa" FBgn0000365 cpw canopy wing http://flybase.org/reports/FBgn0000365 - gene - - - cpw - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,partially lethal - majority die,visible,recessive,viable,male,reduced" "wing,wing vein,eye,ocellar bristle,thorax,adult thorax,macrochaeta,microchaeta,head bristle" FBgn0031268 cold coiled http://flybase.org/reports/FBgn0031268 protein_coding_gene - "wound healing ; GO:0042060 | inferred from mutant phenotype maintenance of permeability of blood-brain barrier ; GO:0035633 | inferred from direct assay establishment of blood-brain barrier ; GO:0060856 | inferred from direct assay septate junction assembly ; GO:0019991 | inferred from direct assay septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay "CG2813, cold, cg2813, leaky4" - CG2813 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-134a4.1, Drer\si:ch211-134a4.5, Drer\negaly6, Drer\LOC100535423, Drer\si:ch211-134a4.2, Drer\si:dkeyp-80c12.8, Drer\si:dkey-102g19.3" - - - "Mmus\Pinlyp, Mmus\2210407C18Rik, Mmus\1810065E05Rik, Mmus\4930504O13Rik, Mmus\Gm12253, Mmus\Lypd8" "Hsap\PINLYP, Hsap\LYPD8" "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval dorsal trunk,presumptive embryonic/larval tracheal system,subperineurial glial cell,trichogen cell" FBgn0000333 cmd carminoid http://flybase.org/reports/FBgn0000333 - gene - - - cmd - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0025870 C141 C141 http://flybase.org/reports/FBgn0025870 - gene - adult walking behavior ; GO:0007628 | traceable author statement - C141 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069929 CG41122 - http://flybase.org/reports/FBgn0069929 protein_coding_gene - - - CG41122 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014932 anon-87Ea anon-87Ea http://flybase.org/reports/FBgn0014932 - gene - - - "A, anon-87Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003139 PpV Protein phosphatase V http://flybase.org/reports/FBgn0003139 - protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006186 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence model" mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from genetic interaction with SGD:S000002205 protein dephosphorylation ; GO:0006470 | inferred from sequence model cytoplasm ; GO:0005737 | inferred from direct assay "DmPpV-6A, CG12217, PPV, PPPV6A, PPV 6A, PpV, Ppv, dPP6, PP6, PpV[[C]]" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG12217 11-Aug-17 DroID_v2017_08 "Drer\zgc:56064, Drer\ppp4ca, Drer\ppp6c, Drer\ppp2ca, Drer\ppp4cb, Drer\ppp2cb" "Scer\YNL217W, Scer\SIT4, Scer\PPH22, Scer\PPH3, Scer\PPH21" "Cele\pph-6, Cele\pph-4.1, Cele\pph-4.2" "Xtro\ppp4c, Xtro\ppp6c, Xtro\ppp2ca, Xtro\ppp2cb" "Mmus\Ppp2ca, Mmus\Ppp4c, Mmus\Ppp6c, Mmus\Ppp2cb" "Hsap\PPP2CA, Hsap\PPP6C, Hsap\PPP2CB" " embryonic stage | stage 5 , embryonic stage -- adult stage , embryonic stage | stage 4 " organism

" embryonic stage | stage 4 , embryonic stage | stage 5 " organism

"visible,viable" "wing,trichogen cell" FBgn0267727 Pen Pendulin http://flybase.org/reports/FBgn0267727 protein_coding_gene nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 lymph gland development ; GO:0048542 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | inferred from mutant phenotype nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 cytoplasm ; GO:0005737 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "imp-alpha2, l(2)k06324, Pen, CG4799, imp alpha2, alpha2, Imp-alpha2, Kap-alpha2, oho-31, bs29g06.y1, importin alpha2/pendulin, Kap alpha2, oho31, Dimp-alpha2, 2.1, alpha2A-Kap, OHO31, DPend, Oho31, pen-2, pen, l(2)144/1, l(2)k14401, anon-WO0140519.258, IMPalpha2, Kpna2, Rch1, impalpha2, Dalpha2, alphaKap2" "IPR000225:Armadillo, IPR002652:Importin-alpha, importin-beta-binding domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024931:Importin subunit alpha, IPR032413:Atypical Arm repeat" CG4799 11-Aug-17 DroID_v2017_08 "Drer\kpna5, Drer\kpna1, Drer\kpna2, Drer\kpna3, Drer\spag6, Drer\kpna6, Drer\kpna7" Scer\SRP1 "Cele\ima-2, Cele\ima-3" "Xtro\armc3, Xtro\kpna2, Xtro\spag6, Xtro\kpna3, Xtro\kpna6, Xtro\kpna7, Xtro\kpna1, Xtro\kpna4" "Mmus\Kpna6, Mmus\Kpna1, Mmus\Kpna4, Mmus\Kpna7, Mmus\Spag6, Mmus\Spag6l, Mmus\Kpna2, Mmus\Kpna3" "Hsap\KPNA4, Hsap\KPNA7, Hsap\KPNA5, Hsap\KPNA1, Hsap\KPNA3, Hsap\KPNA2, Hsap\SPAG6, Hsap\KPNA6" " embryonic stage | early , adult stage , embryonic stage | stage >12 , larval stage | third instar , embryonic stage | gastrula , embryonic stage | embryonic cycle 10-13 , embryonic stage | extended germ band , embryonic stage | 0-2 hr , embryonic stage -- adult stage " " ventral nerve cord

, lymph gland

,organism | segmentally repeated , larval brain | restricted

, embryonic brain | restricted

, pole cell

, ventral nerve cord primordium

, imaginal disc

,

ubiquitous , neuroblast

, ring gland

" " embryonic stage -- adult stage , embryonic stage && larval stage && adult stage " FBgn0044102 E(rst)C463 E(rst)C463 http://flybase.org/reports/FBgn0044102 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C463, E(rst)C463" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0044500 DTD44.3 DTD44.3 http://flybase.org/reports/FBgn0044500 gene - - - DTD44.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265078 CR44189 - http://flybase.org/reports/FBgn0265078 non_protein_coding_gene - - - "CR44189, lincRNA.197" - CR44189 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264523 ff14 - http://flybase.org/reports/FBgn0264523 gene - - - ff14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" spermatid FBgn0061507 l(2)24Ac lethal (2) 24Ac http://flybase.org/reports/FBgn0061507 gene - - - l(2)24Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060348 l(3)S142814b lethal (3) S142814b http://flybase.org/reports/FBgn0060348 gene - - - "1428/14, l(3)S142814b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262549 Mod(GMroX1)B - http://flybase.org/reports/FBgn0262549 gene - - - Mod(GMroX1)B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female,recessive,male" FBgn0027196 l(2)32e lethal (2) 32e http://flybase.org/reports/FBgn0027196 - gene - - - "l[32e], l(2)32e" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032216 Usp14 Ubiquitin specific protease 14 http://flybase.org/reports/FBgn0032216 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:12612 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein ubiquitination ; GO:0016567 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:12612 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG5384, DmUsp14, Ubp6p, Usp14, Q9VKZ8" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain, IPR029071:Ubiquitin-related domain" CG5384 11-Aug-17 DroID_v2017_08 "Drer\ublcp1, Drer\ubfd1, Drer\usp19, Drer\usp14" "Scer\UBP2, Scer\UBP6" Cele\usp-14 "Xtro\usp14, Xtro\ublcp1" "Mmus\Usp14, Mmus\Ublcp1, Mmus\Ubfd1, Mmus\Usp19" "Hsap\USP19, Hsap\UBLCP1, Hsap\UBFD1, Hsap\USP14" "viable,fertile,locomotor behavior defective,short lived" FBgn0051228 tRNA:Pro-TGG-1-5 transfer RNA:Proline-TGG 1-5 http://flybase.org/reports/FBgn0051228 tRNA_gene CCA codon-amino acid adaptor activity ; GO:0033423 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033423 cytosol ; GO:0005829 | inferred by curator from GO:0033423 "AE002708.trna42-ProTGG, tRNA:P:TGG:AE002708-d, CR31228, chr3R.trna48-ProTGG, tRNA-Pro-TGG-1-5, tRNA:Pro-TGG-1-5, tRNA:CR31228, CCA" - CR31228 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022096 l(2)k07215 lethal (2) k07215 http://flybase.org/reports/FBgn0022096 - gene - - - l(2)k07215 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260253 GSd334 - http://flybase.org/reports/FBgn0260253 gene - - - GSd334 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037039 CG10587 - http://flybase.org/reports/FBgn0037039 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 extracellular space ; GO:0005615 | inferred from direct assay "SP167, CG10587" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG10587 11-Aug-17 DroID_v2017_08 Drer\tmprss2 - "Cele\try-5, Cele\try-1, Cele\svh-1" - Mmus\Gzma Hsap\GZMA "viable,fertile" FBgn0040671 CG12569 - http://flybase.org/reports/FBgn0040671 protein_coding_gene - - - CG12569 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038565 CG7794 - http://flybase.org/reports/FBgn0038565 protein_coding_gene "structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002452 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002452, InterPro:IPR008280 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002452" "microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002452 microtubule ; GO:0005874 | inferred from sequence or structural similarity" "anon-WO0140519.191, CG7794, Tub1B" "IPR000217:Tubulin, IPR002452:Alpha tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain" CG7794 11-Aug-17 DroID_v2017_08 "Drer\tuba8l, Drer\tuba1b, Drer\tuba2, Drer\si:ch211-114n24.6, Drer\tuba4l, Drer\tuba8l2, Drer\tuba1a, Drer\tuba7l, Drer\tuba1c, Drer\si:ch73-199e17.1" "Scer\TUB3, Scer\TUB1" "Cele\mec-12, Cele\tba-4, Cele\tba-9, Cele\tba-6, Cele\tba-5, Cele\tba-8" "Xtro\tuba4a, Xtro\tuba3c, Xtro\tuba4, Xtro\tuba1c, Xtro\tuba3e, Xtro\tubal3, Xtro\tuba1a, Xtro\tuba8, Xtro\tuba4b" "Mmus\Tuba3b, Mmus\Tuba1c, Mmus\Tuba1b, Mmus\Tuba1a, Mmus\Tuba3a, Mmus\Tuba4a, Mmus\Tubal3, Mmus\Tuba8" "Hsap\TUBA4A, Hsap\TUBA3E, Hsap\TUBA1B, Hsap\TUBA8, Hsap\TUBA1C, Hsap\TUBA1A, Hsap\TUBAL3, Hsap\TUBA3C, Hsap\TUBA3D" viable FBgn0065602 l(2)SH0865 lethal (2) SH0865 http://flybase.org/reports/FBgn0065602 gene - - - "l(2)SH0865, l(2)SH2 0865" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000959 fs(2)E6 female sterile (2) E6 http://flybase.org/reports/FBgn0000959 - gene - - - "fs2.6, fs(2)E6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" egg FBgn0262464 mir-6-1 mir-6-1 stem loop http://flybase.org/reports/FBgn0262464 miRNA_gene - negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype - "mir-6-1, mir-6, 6-1, Dme-miR-6, miR-6-1, CR43047, miR-6, miR6-1, CR33004, dme-mir-6-1" - CR43047 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , larval stage | first instar " visible chaeta FBgn0267250 l(3)j13C8 - http://flybase.org/reports/FBgn0267250 gene - - - l(3)j13C8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086448 PIG-Q Phosphatidylinositol glycan anchor biosynthesis class Q http://flybase.org/reports/FBgn0086448 protein_coding_gene phosphatidylinositol N-acetylglucosaminyltransferase activity ; GO:0017176 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000481757 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with HGNC:14135 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007720 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with HGNC:14135 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506 | inferred from biological aspect of ancestor with PANTHER:PTN000481757 "l(1)14Ca, Dm_CAC10056/216-441, dGpi1, CG32578, l(1)i19, l(1)i19e, l(1)19-134, l(1)14Cd, i19e, PIG-Q, Gpi1" IPR007720:N-acetylglucosaminyl transferase component CG32578 11-Aug-17 DroID_v2017_08 Drer\pigq Scer\GPI1 Cele\F01G4.5 Xtro\pigq Mmus\Pigq Hsap\PIGQ FBgn0008639 66Dem 66Dem http://flybase.org/reports/FBgn0008639 - gene - - - 66Dem - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266466 cashew - http://flybase.org/reports/FBgn0266466 gene - - - cashew - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cell polarity defective,germline clone" "egg chamber,germline clone,oocyte,centrosome | germline clone" FBgn0046846 dec-1::Dvir\dec-1 dec-1::Dvir\dec-1 http://flybase.org/reports/FBgn0046846 engineered_fusion_gene - - - dec-1::Dvir\dec-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004794 war warbler http://flybase.org/reports/FBgn0004794 - gene molecular_function ; GO:0003674 | no biological data available ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available war - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0030137 CG15317 - http://flybase.org/reports/FBgn0030137 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15317 - CG15317 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000280 Cec-Psi1 Cecropin pseudogene 1 http://flybase.org/reports/FBgn0000280 - pseudogene_attribute - - - "CecPsi1, cec-Psi1, CR32926, Cec-Psi1" - CR32926 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015985 l(2)PC4-N lethal (2) PC4-N http://flybase.org/reports/FBgn0015985 - gene - - - "fs(2)PC4-N, l(2)PC4-N" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0085318 CG34289 - http://flybase.org/reports/FBgn0085318 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34289 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR017907:Zinc finger, RING-type, conserved site" CG34289 11-Aug-17 DroID_v2017_08 "Drer\trim35-19, Drer\si:ch73-106l15.2, Drer\trim35-24, Drer\LOC100536643, Drer\trim35-34, Drer\trim35-10, Drer\trim35-31, Drer\trim35-29, Drer\trim35-14, Drer\si:ch211-175l6.2, Drer\trim35-25, Drer\trim35-35, Drer\trim35-9, Drer\si:ch211-12p12.2, Drer\trim35-28, Drer\trim35-3, Drer\rnf4, Drer\trim35-7, Drer\trim35-13, Drer\trim35-30, Drer\trim35-1, Drer\ftr70, Drer\si:ch73-166o21.1, Drer\si:ch1073-324l1.1, Drer\trim35-12, Drer\trim35-20, Drer\trim35-33, Drer\si:ch73-106l15.3, Drer\trim35-23" - "Cele\C28G1.6, Cele\T01G5.7, Cele\Y38C1AA.6" "Xtro\trim69.2, Xtro\rnf4" "Mmus\Trim35, Mmus\Trim7, Mmus\Trim10, Mmus\Rnf4, Mmus\Trim26" "Hsap\TRIM26, Hsap\RNF4, Hsap\TRIM10, Hsap\TRIM7, Hsap\TRIM35" FBgn0000749 fs(1)A336 female sterile (1) A336 http://flybase.org/reports/FBgn0000749 - gene - - - "fs(1)336, fs(1)A336" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" egg FBgn0051956 pgant4 polypeptide GalNAc transferase 4 http://flybase.org/reports/FBgn0051956 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay positive regulation of secretion ; GO:0051047 | inferred from mutant phenotype protein O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype secretory granule organization ; GO:0033363 | inferred from mutant phenotype oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement "CG31956, CG8845b, CG8845, pgant4" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG31956 11-Aug-17 DroID_v2017_08 "Drer\LOC101886587, Drer\galnt14, Drer\galnt6, Drer\LOC101882942, Drer\galnt16, Drer\galnt8b, Drer\galnt1, Drer\galnt7, Drer\LOC568645, Drer\galnt2, Drer\poc1bl, Drer\galnt18b, Drer\LOC103910015, Drer\LOC100535692, Drer\galnt12, Drer\galnt8a.1, Drer\galnt10, Drer\wbscr17, Drer\galnt3, Drer\galnt13, Drer\galnt11, Drer\LOC100334784, Drer\si:ch211-15e22.3, Drer\galnt9" - "Cele\gly-10, Cele\gly-7, Cele\gly-9, Cele\gly-11, Cele\gly-3" "Xtro\galnt1, Xtro\galnt13, Xtro\galnt7, Xtro\wbscr17, Xtro\galnt16, Xtro\galnt4, Xtro\galnt2, Xtro\galnt10, Xtro\galnt9, Xtro\galnt14, Xtro\galnt12, Xtro\galnt15, Xtro\galnt6.1" "Mmus\Galntl5, Mmus\Galnt16, Mmus\Galnt6, Mmus\Galnt18, Mmus\Galnt10, Mmus\Galnt13, Mmus\Galnt9, Mmus\Galnt2, Mmus\Galnt1, Mmus\Galntl6, Mmus\Galnt4, Mmus\Galnt15, Mmus\Galnt14, Mmus\Galnt11, Mmus\Galnt3, Mmus\Galnt7, Mmus\Wbscr17, Mmus\Galnt12, Mmus\Galnt5" "Hsap\GALNT6, Hsap\GALNT4, Hsap\GALNTL6, Hsap\GALNT14, Hsap\WBSCR17, Hsap\GALNT12, Hsap\GALNT9, Hsap\GALNT2, Hsap\GALNT7, Hsap\GALNT16, Hsap\GALNT10, Hsap\POC1B-GALNT4, Hsap\GALNTL5, Hsap\GALNT5, Hsap\GALNT18, Hsap\GALNT11, Hsap\GALNT1, Hsap\GALNT3, Hsap\GALNT13, Hsap\GALNT8, Hsap\GALNT15" "lethal,viable" "embryonic/larval proventriculus outer layer,secretory granuleunspecified,secretory granuletim-02)" FBgn0030905 CG15059 - http://flybase.org/reports/FBgn0030905 protein_coding_gene - - - CG15059 - CG15059 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262410 mir-6-2 mir-6-2 stem loop http://flybase.org/reports/FBgn0262410 miRNA_gene - negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype - "mir-6-2, mir-6, 6-2, Dme-miR-6, miR-6-2, CR42954, miR-6, miR6-2, CR33040, dme-mir-6-2" - CR42954 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , larval stage | first instar " "visible,lethal" wing FBgn0011632 l(2)T57h10 lethal (2) T57h10 http://flybase.org/reports/FBgn0011632 FBgn0005177 gene - - - l(2)T57h10 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000309 chl chaetelle http://flybase.org/reports/FBgn0000309 - gene - - - chl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,female sterile" "macrochaeta,wing vein,genitalia,adult abdomen" FBgn0039459 IntS12 Integrator 12 http://flybase.org/reports/FBgn0039459 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 snRNA 3'-end processing ; GO:0034472 | inferred from direct assay snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:25067 neurogenesis ; GO:0022008 | inferred from mutant phenotype integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:25067 "CG5491, IntS12, Int12" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5491 11-Aug-17 DroID_v2017_08 "Drer\phf1, Drer\phf19, Drer\ints12, Drer\mtf2" - "Cele\phf-30, Cele\F53H1.4" "Xtro\phf19, Xtro\ints12, Xtro\phf1, Xtro\mtf2" "Mmus\Ints12, Mmus\Phf1, Mmus\Mtf2, Mmus\Phf19" "Hsap\INTS12, Hsap\PHF19, Hsap\MTF2, Hsap\PHF1" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0000062 alb alberich http://flybase.org/reports/FBgn0000062 - gene molecular_function ; GO:0003674 | no biological data available blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available alb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" "embryonic abdominal segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11" FBgn0266502 s-256 - http://flybase.org/reports/FBgn0266502 gene - - - s-256 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259544 B2009 - http://flybase.org/reports/FBgn0259544 gene - - - B2009 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266906 CR45366 - http://flybase.org/reports/FBgn0266906 non_protein_coding_gene - - - CR45366 - CR45366 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038384 CG5470 - http://flybase.org/reports/FBgn0038384 protein_coding_gene - - - CG5470 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267973 Ncoa6::sd - http://flybase.org/reports/FBgn0267973 engineered_fusion_gene - - - Ncoa6::sd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084094 E-3c1 Enhancer on chromosome 3-complementation group c1 http://flybase.org/reports/FBgn0084094 gene - - - "E-3c, E-3c1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082581 twiggy twiggy http://flybase.net/reports/FBgn0082581.html gene 0006909=phagocytosis 11-Aug-17 DroID_v2017_08 FBgn0065161 l(3)SH043 lethal (3) SH043 http://flybase.org/reports/FBgn0065161 gene - - - "l(3)SH043, l(2)SH3 043" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060661 l(3)S082414a lethal (3) S082414a http://flybase.org/reports/FBgn0060661 gene - - - "0824/14, l(3)S082414a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0016810 l(1)L11 lethal (1) L11 http://flybase.org/reports/FBgn0016810 - gene - - - "l(1)L11, L11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001339 l(1)1Bg lethal (1) 1Bg http://flybase.org/reports/FBgn0001339 - gene - - - "l(1)Bg, l(1)1Bg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051065 ppk31 pickpocket 31 http://flybase.org/reports/FBgn0051065 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG31065, ppk31" "IPR001873:Epithelial sodium channel, IPR017896:4Fe-4S ferredoxin-type, iron-sulphur binding domain" CG31065 11-Aug-17 DroID_v2017_08 "Drer\asic4a, Drer\asic1b, Drer\asic2, Drer\asic1a, Drer\asic1c, Drer\asic4b" - "Cele\acd-1, Cele\del-7, Cele\delm-1, Cele\acd-5, Cele\delm-2, Cele\acd-4, Cele\flr-1, Cele\acd-2" "Xtro\scnn1g, Xtro\scnn1b, Xtro\asic4, Xtro\scnn1a, Xtro\scnn1d, Xtro\asic5, Xtro\asic1" "Mmus\Asic2, Mmus\Scnn1b, Mmus\Asic1, Mmus\Asic5, Mmus\Asic3, Mmus\Scnn1a, Mmus\Asic4, Mmus\Scnn1g" "Hsap\SCNN1D, Hsap\ASIC3, Hsap\ASIC1, Hsap\ASIC2, Hsap\SCNN1B, Hsap\SCNN1G, Hsap\SCNN1A, Hsap\ASIC5, Hsap\ASIC4" "viable,lethal" DRSC13811 I 1.689848384 0.073480041 1.317502813 0.452099998 -0.243868111 0.013649685 FBgn0039799 CG15543 - http://flybase.org/reports/FBgn0039799 protein_coding_gene nucleobase-containing compound kinase activity ; GO:0019205 | inferred from electronic annotation with InterPro:IPR000850 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850 nucleobase-containing compound metabolic process ; GO:0006139 | inferred from electronic annotation with InterPro:IPR000850 - CG15543 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000850:Adenylate kinase/UMP-CMP kinase" CG15543 11-Aug-17 DroID_v2017_08 "Drer\ak3, Drer\ak4, Drer\ak2, Drer\ak8, Drer\si:ch211-199m3.4, Drer\ak7b, Drer\ak7a" "Scer\ADK2, Scer\ADK1" - "Xtro\ak8, Xtro\ak9, Xtro\ak7, Xtro\ak3, Xtro\ak4, Xtro\ak2" "Mmus\Ak7, Mmus\Ak9, Mmus\Ak8, Mmus\Ak4, Mmus\Ak2, Mmus\Ak3" "Hsap\AK9, Hsap\AK7, Hsap\AK8, Hsap\AK3, Hsap\AK4, Hsap\AK2" viable FBgn0069446 E(br)420 E(br)420 http://flybase.org/reports/FBgn0069446 gene - - - E(br)420 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029139 P(3)98DF P(3)98DF http://flybase.org/reports/FBgn0029139 gene - - - P(3)98DF - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267137 CR45577 - http://flybase.org/reports/FBgn0267137 non_protein_coding_gene - - - CR45577 - CR45577 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060984 l(3)S028218b lethal (3) S028218b http://flybase.org/reports/FBgn0060984 gene - - - "0282/18, l(3)S028218b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040246 anon-57Bb anon-57Bb http://flybase.org/reports/FBgn0040246 gene - - - anon-57Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030307 CG33235 - http://flybase.org/reports/FBgn0030307 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15192, CG33235" - CG33235 11-Aug-17 DroID_v2017_08 Drer\aim1b - - - - - "viable,partially lethal - majority die,some die during pupal stage" FBgn0015425 l(1)1CDb lethal (1) 1CDb http://flybase.org/reports/FBgn0015425 - gene - - - l(1)1CDb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001879 l(1)YD23b lethal (1) YD23b http://flybase.org/reports/FBgn0001879 - gene - - - "l(1)YD23, l(1)YD23b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016053 pgc polar granule component http://flybase.org/reports/FBgn0016053 FBgn0034719 protein_coding_gene - "pole cell migration ; GO:0007280 | inferred from mutant phenotype pole cell development ; GO:0007277 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay germ cell development ; GO:0007281 | inferred from mutant phenotype" P granule ; GO:0043186 | non-traceable author statement pole plasm ; GO:0045495 | traceable author statement pole plasm ; GO:0045495 | inferred from direct assay P granule ; GO:0043186 | traceable author statement P granule ; GO:0043186 | inferred from direct assay "pgc-1, Pgc, pgr, Pgc1, CG11296, CR32885, pgc, CG32885" - CG32885 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "mesothoracic tergum,pole cell,gonad" DRSC04099 E -1.48869092 0.286435893 3.129323254 0.228627332 0.121689279 -0.579230664 FBgn0265001 ppk18 pickpocket 18 http://flybase.org/reports/FBgn0265001 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG13120, CG13121, ppk18, CG44152" IPR001873:Epithelial sodium channel CG44152 11-Aug-17 DroID_v2017_08 "Drer\asic2, Drer\asic4a, Drer\asic1a, Drer\asic4b, Drer\asic1b, Drer\asic1c" - "Cele\delm-2, Cele\acd-5, Cele\acd-2, Cele\acd-4, Cele\acd-1, Cele\delm-1, Cele\del-7, Cele\flr-1" "Xtro\scnn1b, Xtro\scnn1g, Xtro\asic4, Xtro\asic5, Xtro\scnn1a, Xtro\scnn1d, Xtro\asic1" "Mmus\Scnn1a, Mmus\Asic1, Mmus\Asic4, Mmus\Scnn1b, Mmus\Asic2, Mmus\Asic3, Mmus\Asic5, Mmus\Scnn1g" "Hsap\ASIC1, Hsap\SCNN1G, Hsap\SCNN1B, Hsap\ASIC3, Hsap\ASIC2, Hsap\SCNN1A, Hsap\SCNN1D, Hsap\ASIC4, Hsap\ASIC5" FBgn0058445 CG40445 - http://flybase.org/reports/FBgn0058445 protein_coding_gene - - - CG40445 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031125 CG11692 - http://flybase.org/reports/FBgn0031125 protein_coding_gene - - - CG11692 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20484 K 0.849424643 -0.142604461 0.044316624 0.13591258 -0.469378822 -1.725126463 FBgn0267499 5.8SrRNA:CR45839 5.8S ribosomal RNA:CR45839 http://flybase.org/reports/FBgn0267499 rRNA_gene - - - "5.8SrRNA:CR45839, CR45839" - CR45839 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052576 CG32576 - http://flybase.org/reports/FBgn0052576 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vesicle-mediated transport ; GO:0016192 | inferred from electronic annotation with InterPro:IPR007305 cellular_component ; GO:0005575 | no biological data available "NEST:bs01h05, anon-AE003501.1, BcDNA:RE29988, CG32576" "IPR007305:Vesicle transport protein, Got1/SFT2-like" CG32576 11-Aug-17 DroID_v2017_08 "Drer\golt1bb, Drer\golt1a, Drer\golt1ba" Scer\GOT1 Cele\F41C3.4 Xtro\golt1b "Mmus\Golt1b, Mmus\Golt1a" "Hsap\GOLT1B, Hsap\GOLT1A" DRSC19136 K 0.084884855 0.342205001 0.130742592 -0.608990982 0.120520048 1.589680424 FBgn0033104 CG15237 - http://flybase.org/reports/FBgn0033104 protein_coding_gene - regulation of mitotic cell cycle spindle assembly checkpoint ; GO:0090266 | inferred from electronic annotation with InterPro:IPR026182 anaphase-promoting complex ; GO:0005680 | inferred from electronic annotation with InterPro:IPR026182 "CG15237, APC15" IPR026182:Anaphase-promoting complex subunit 15 CG15237 11-Aug-17 DroID_v2017_08 Drer\anapc15 - - - Mmus\Anapc15 Hsap\ANAPC15 viable FBgn0040630 CG12710 - http://flybase.org/reports/FBgn0040630 protein_coding_gene - - - CG12710 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021790 l(2)rAO135 lethal (2) rAO135 http://flybase.net/reports/FBgn0021790.html gene l(2)rA135 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0052029 Cpr66D Cuticular protein 66D http://flybase.org/reports/FBgn0052029 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG6458, CG6469, Cpr66D, CG32029, DmelCpr66D" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG32029 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "viable,fertile" FBgn0040336 Seipin Seipin http://flybase.org/reports/FBgn0040336 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to starvation ; GO:0042594 | inferred from mutant phenotype fatty acid beta-oxidation ; GO:0006635 | inferred from mutant phenotype regulation of lipid biosynthetic process ; GO:0046890 | inferred from mutant phenotype inferred from genetic interaction with mdy inferred from genetic interaction with mino inferred from genetic interaction with SCAP regulation of triglyceride metabolic process ; GO:0090207 | inferred from mutant phenotype lipid biosynthetic process ; GO:0008610 | inferred from mutant phenotype positive regulation of lipid storage ; GO:0010884 | inferred from mutant phenotype endoplasmic reticulum calcium ion homeostasis ; GO:0032469 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype phosphatidic acid metabolic process ; GO:0046473 | inferred from mutant phenotype diacylglycerol metabolic process ; GO:0046339 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay "EG:BACR7C10.1, CG9904, Seipin, dSeipin" IPR009617:Seipin family CG9904 11-Aug-17 DroID_v2017_08 "Drer\bscl2l, Drer\bscl2" - Cele\R01B10.6 Xtro\bscl2 Mmus\Bscl2 Hsap\BSCL2 "decreased cell size,somatic clone,viable,fertile,lethal,nutrition conditional" "adult fat body,somatic clone,lipid particle | somatic clone,embryonic/larval fat body,nutrition conditional,fat body,salivary gland,lipid particle | ectopic,lipid particle,lipid particle | ectopicppl.PP,lipid particleppl.PP,lipid particle | ectopicelav.PU,lipid particle | ectopic48Y" FBgn0019731 l(1)A17 lethal (1) A17 http://flybase.org/reports/FBgn0019731 - gene - - - l(1)A17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028086 l(3)S084805 lethal (3) S084805 http://flybase.org/reports/FBgn0028086 gene - - - "0848/05, l(3)S084805" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0283680 IP3K2 "Inositol 1,4,5-triphosphate kinase 2" http://flybase.org/reports/FBgn0283680 protein_coding_gene "calcium-dependent protein binding ; GO:0048306 | inferred from direct assay calmodulin binding ; GO:0005516 | inferred from direct assay inositol-1,4,5-trisphosphate 3-kinase activity ; GO:0008440 | inferred from direct assay" salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype inferred from genetic interaction with mir-14 inositol phosphate biosynthetic process ; GO:0032958 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "wy, IP3K2, CG15745, ip3k2, CG45017, dmIP[[3]]beta, CG1630, IP[[3]]K2, CG34359, dmIP3Kbeta, dmIP3K2, DIP3K2, D-IP3K2, CG12724, NP2758, IP[[3]]K-2, CG4501" "IPR005522:Inositol polyphosphate kinase, IPR011989:Armadillo-like helical" CG45017 11-Aug-17 DroID_v2017_08 "Drer\itpka, Drer\itpkcb, Drer\itpkb, Drer\itpkca, Drer\si:ch73-22a13.3" - Cele\lfe-2 "Xtro\itpkb, Xtro\itpka, Xtro\itpkc" "Mmus\Itpkb, Mmus\Itpka, Mmus\Itpkc" "Hsap\ITPKB, Hsap\ITPKA, Hsap\ITPKC" "visible,viable,fertile,lethal,male" "wing,abdomen,wing vein L1" FBgn0066330 rafl rafael http://flybase.org/reports/FBgn0066330 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype visual learning ; GO:0008542 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available rafl - - 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,visual behavior defective,recessive,learning defective,neurophysiology defective,chemical sensitive" FBgn0050042 Cpr49Ab Cuticular protein 49Ab http://flybase.org/reports/FBgn0050042 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG8496, Cpr49Ab, CG30042, DmelCpr49Ab" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG30042 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0040132 l(2)22Ag lethal (2) 22Ag http://flybase.org/reports/FBgn0040132 gene - - - "A, l(2)22Ag" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038535 alt aluminum tubes http://flybase.org/reports/FBgn0038535 protein_coding_gene receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN001450043 "cuticle development ; GO:0042335 | inferred from genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN001450043" lipid particle ; GO:0005811 | inferred from direct assay ribosome ; GO:0005840 | inferred from biological aspect of ancestor with PANTHER:PTN001450043 endomembrane system ; GO:0012505 | inferred from direct assay integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN001450043 "CG18212, alt, Q9VEH0_DROME" - CG18212 11-Aug-17 DroID_v2017_08 "Drer\rrbp1b, Drer\rrbp1a" - - Xtro\rrbp1 "Mmus\Ktn1, Mmus\Rrbp1" Hsap\RRBP1 "viable,fertile" FBgn0261850 Xpd Xeroderma pigmentosum D http://flybase.org/reports/FBgn0261850 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001945, InterPro:IPR002464, InterPro:IPR006555, InterPro:IPR010614, InterPro:IPR014013 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001945, InterPro:IPR010614 transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent 5'-3' DNA helicase activity ; GO:0043141 | inferred from sequence or structural similarity with SGD:S000000973" transcriptional open complex formation at RNA polymerase II promoter ; GO:0001113 | inferred from sequence or structural similarity with HGNC:3434 response to UV ; GO:0009411 | inferred from direct assay regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | inferred from mutant phenotype promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from sequence or structural similarity with HGNC:3434 nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity with HGNC:3434 inferred from sequence or structural similarity with SGD:S000000973 regulation of chromosome segregation ; GO:0051983 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:3434 inferred from sequence or structural similarity with SGD:S000000973 negative regulation of G2/M transition of mitotic cell cycle ; GO:0010972 | inferred from direct assay response to UV ; GO:0009411 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from direct assay "polytene chromosome interband ; GO:0005705 | inferred from direct assay core TFIIH complex ; GO:0000439 | inferred from sequence or structural similarity with HGNC:3434 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from physical interaction with hay, CycH, Mat1, mrn, Cdk7 holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with SGD:S000000973 polytene chromosome puff ; GO:0005703 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay core TFIIH complex ; GO:0000439 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:3434 inferred from sequence or structural similarity with SGD:S000000973" "Xpd, l(2)SH2137, xpd, XPD, XPD/ERCC2, CG9433, DmXPD, DhXPD, DhR3, ERCC2, l(2)SH2 2137" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001945:RAD3/XPD family, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR006554:Helicase-like, DEXD box c2 type, IPR006555:ATP-dependent helicase, C-terminal, IPR010643:Helical and beta-bridge domain, IPR013020:DNA helicase (DNA repair), Rad3 type, IPR014013:Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, IPR010614:DEAD2" CG9433 11-Aug-17 DroID_v2017_08 Drer\ercc2 Scer\RAD3 "Cele\Y50D7A.11, Cele\xpd-1" Xtro\ercc2 Mmus\Ercc2 Hsap\ERCC2 " embryonic stage | syncytial blastoderm , larval stage | third instar , embryonic stage | stage 5 , embryonic stage | stage >5 " "

ubiquitous , larval salivary gland

,

, embryonic/larval fat body

" FBgn0003188 qui quit http://flybase.org/reports/FBgn0003188 - gene molecular_function ; GO:0003674 | no biological data available ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available qui - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "nurse follicle cell,ovary" FBgn0017420 su(RpII215)S3 su(RpII215)S3 http://flybase.org/reports/FBgn0017420 - gene - - - "S3, anon-S3/S13, su(RpII215)S3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038248 CG7886 - http://flybase.org/reports/FBgn0038248 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN001189119 centrosome ; GO:0005813 | inferred from sequence or structural similarity with HGNC:25740 "anon-WO0140519.200, CG7886" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR026212:Centrosomal protein of 78kDa" CG7886 11-Aug-17 DroID_v2017_08 "Drer\nod1, Drer\si:ch211-81a5.5, Drer\nlrx1, Drer\tonsl, Drer\si:dkey-23k10.3, Drer\lrrc34, Drer\nlrc3l, Drer\si:ch211-122c9.5, Drer\nod2, Drer\lrrc45, Drer\LOC101884653, Drer\cep78, Drer\nlrc3, Drer\ciita" - - "Xtro\nlrx1, Xtro\LOC100485518, Xtro\cep78, Xtro\lrrc31, Xtro\lrrc34, Xtro\tonsl, Xtro\lrrc45, Xtro\nod1" "Mmus\Cep78, Mmus\Lrrc74b, Mmus\Nlrp9c, Mmus\Nlrp4f, Mmus\Tonsl, Mmus\Lrrc71, Mmus\Lrrc74a, Mmus\Nod2, Mmus\Nlrc3, Mmus\Lrrc45, Mmus\Nlrp4c, Mmus\Nlrx1, Mmus\Ciita, Mmus\Nod1, Mmus\Nlrp4a, Mmus\Nlrp9a, Mmus\Lrrc34, Mmus\Nlrp14, Mmus\Nlrp4e, Mmus\Nlrp9b, Mmus\Lrrc31, Mmus\Rnh1" "Hsap\NOD2, Hsap\LRRC71, Hsap\LRRC74A, Hsap\CEP78, Hsap\NOD1, Hsap\TONSL, Hsap\LRRC45, Hsap\NLRP4, Hsap\NLRC5, Hsap\LRRC31, Hsap\CIITA, Hsap\NLRX1, Hsap\LRRC34, Hsap\NLRP14, Hsap\RNH1, Hsap\NLRP9" viable FBgn0013570 l(3)78Da lethal (3) 78Da http://flybase.org/reports/FBgn0013570 - gene - - - l(3)78Da - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0084254 E-3c4 Enhancer on chromosome 3-complementation group c4 http://flybase.org/reports/FBgn0084254 gene - - - "E-3c, E-3c4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065259 l(2)SH2089 lethal (2) SH2089 http://flybase.org/reports/FBgn0065259 gene - - - l(2)SH2089 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262107 CR42860 - http://flybase.org/reports/FBgn0262107 non_protein_coding_gene - - - CR42860 - CR42860 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001598 l(1)CP8 lethal (1) CP8 http://flybase.org/reports/FBgn0001598 - gene - - - l(1)CP8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021843 l(2)k14816 lethal (2) k14816 http://flybase.org/reports/FBgn0021843 - gene - - - l(2)k14816 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035799 CG14838 - http://flybase.org/reports/FBgn0035799 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - CG14838 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG14838 11-Aug-17 DroID_v2017_08 Drer\wdr63 - Cele\pfs-2 "Xtro\wdr63, Xtro\LOC101732357" Mmus\Wdr63 Hsap\WDR63 "viable,fertile" FBgn0085398 ppk9 pickpocket 9 http://flybase.org/reports/FBgn0085398 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG13489, CG13490, ppk9, CG34369" IPR001873:Epithelial sodium channel CG34369 11-Aug-17 DroID_v2017_08 "Drer\asic1b, Drer\asic4a, Drer\asic2, Drer\asic1a, Drer\asic1c, Drer\asic4b" - "Cele\acd-1, Cele\flr-1, Cele\acd-4, Cele\del-7, Cele\delm-1, Cele\acd-2, Cele\delm-2, Cele\acd-3, Cele\acd-5" "Xtro\scnn1a, Xtro\asic5, Xtro\asic4, Xtro\scnn1d, Xtro\scnn1b, Xtro\scnn1g, Xtro\asic1" "Mmus\Scnn1b, Mmus\Asic4, Mmus\Asic2, Mmus\Asic3, Mmus\Asic5, Mmus\Scnn1a, Mmus\Asic1, Mmus\Scnn1g" "Hsap\SCNN1G, Hsap\SCNN1A, Hsap\SCNN1B, Hsap\ASIC3, Hsap\SCNN1D, Hsap\ASIC5, Hsap\ASIC1, Hsap\ASIC4, Hsap\ASIC2" DRSC04135 I 1.539440532 -1.736385215 -0.663016632 -1.327574442 -0.028808552 -0.56408249 FBgn0085252 CG34223 - http://flybase.org/reports/FBgn0085252 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34223 - CG34223 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034514 CG13427 - http://flybase.org/reports/FBgn0034514 protein_coding_gene - gastrulation ; GO:0007369 | inferred from expression pattern vesicle ; GO:0031982 | inferred from direct assay CG13427 - CG13427 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070024 BG00488 BG00488 http://flybase.org/reports/FBgn0070024 gene - - - BG00488 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0050201 tRNA:Ser-TGA-1-1 transfer RNA:Serine-TGA 1-1 http://flybase.org/reports/FBgn0050201 tRNA_gene UCA codon-amino acid adaptor activity ; GO:0033407 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033407 cytosol ; GO:0005829 | inferred by curator from GO:0033407 "CR30201, AE002575.trna9-SerTGA, tRNA:S:TGA:AE002575-b, tRNA[[Ser]], chr2R:18579596..18579746, chr2R.trna53-SerTGA, tRNA-Ser-TGA-1-1, tRNA:Ser-TGA-1-1, tRNA:CR30201, UCA" - CR30201 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023110 anon-10Ax anon-10Ax http://flybase.org/reports/FBgn0023110 - gene - - - "17, anon-10Ax" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043849 412\ORF1 412 element ORF1 http://flybase.org/reports/FBgn0043849 transposable_element_gene - - - "412\ORF1, ORF1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031048 CG12237 - http://flybase.org/reports/FBgn0031048 protein_coding_gene pyrophosphatase activity ; GO:0016462 | inferred from sequence or structural similarity with HGNC:16815 phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000467154 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12237, 16769716" "IPR006384:Pyridoxal phosphate phosphatase-related, IPR016965:Phosphatase PHOSPHO-type, IPR023214:HAD-like domain" CG12237 11-Aug-17 DroID_v2017_08 "Drer\phospho2, Drer\phospho1" - "Cele\irld-49, Cele\irld-51, Cele\irld-56, Cele\irld-67, Cele\irld-60, Cele\irld-64, Cele\irld-39, Cele\hpa-1" Xtro\phospho2 "Mmus\Phospho2, Mmus\Phospho1" "Hsap\PHOSPHO1, Hsap\PHOSPHO2" FBgn0029730 boil boilerman http://flybase.org/reports/FBgn0029730 protein_coding_gene molecular_function ; GO:0003674 | no biological data available detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG12681, boil" IPR031732:Protein of unknown function DUF4729 CG12681 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028945 CG7631 - http://flybase.org/reports/FBgn0028945 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" - "BG:BACR44L22.6, CG7631" "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG7631 11-Aug-17 DroID_v2017_08 "Drer\LOC100003133, Drer\LOC797085, Drer\c6ast3, Drer\npsnl, Drer\mep1a.1, Drer\bmp1a, Drer\npsn, Drer\bmp1b, Drer\mep1a.2, Drer\tnfaip6, Drer\he2, Drer\c6ast1, Drer\c6ast4, Drer\si:ch73-40a17.3, Drer\mep1b, Drer\he1b, Drer\he1a, Drer\tll1" - "Cele\nas-6, Cele\nas-4, Cele\nas-39, Cele\nas-13, Cele\Y19D10A.6, Cele\nas-8, Cele\nas-14, Cele\nas-15, Cele\nas-2, Cele\nas-7, Cele\nas-12, Cele\nas-1, Cele\ZC116.3" "Xtro\mep1b, Xtro\bmp1, Xtro\uvs.2, Xtro\accs, Xtro\LOC100492324, Xtro\tll1, Xtro\LOC100489456, Xtro\tll2, Xtro\tnfaip6, Xtro\cubn, Xtro\mep1a" "Mmus\Mep1a, Mmus\Cubn, Mmus\Tll2, Mmus\Adgrg6, Mmus\Tnfaip6, Mmus\Astl, Mmus\Mep1b, Mmus\Tll1, Mmus\Bmp1" "Hsap\ASTL, Hsap\ADGRG6, Hsap\TNFAIP6, Hsap\MEP1B, Hsap\BMP1, Hsap\MEP1A, Hsap\TLL1, Hsap\TLL2, Hsap\CUBN" "viable,visible" "chaeta,supernumerary" FBgn0261566 CG42680 - http://flybase.org/reports/FBgn0261566 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42680 - CG42680 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265723 CR44530 - http://flybase.org/reports/FBgn0265723 non_protein_coding_gene - - - "incRNA.420, CR44530, lincRNA.420" - CR44530 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019878 anon-69Ae anon-69Ae http://flybase.org/reports/FBgn0019878 - gene - - - anon-69Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - larval stage FBgn0062258 SF-1 SF1 boundary element http://flybase.org/reports/FBgn0062258 insulator - - - "SF1, SF-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004793 crpe crepe http://flybase.org/reports/FBgn0004793 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available crpe - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0033498 CG12209 - http://flybase.org/reports/FBgn0033498 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "BcDNA:AT13439, CG12209" - CG12209 11-Aug-17 DroID_v2017_08 - Scer\BXI1 - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0084000 CG41433 - http://flybase.org/reports/FBgn0084000 protein_coding_gene - - - CG41433 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014311 l(3)ry105 lethal (3) ry105 http://flybase.org/reports/FBgn0014311 FBgn0015507 gene - - - "P622, l(3)ry105" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266749 CR45222 - http://flybase.org/reports/FBgn0266749 non_protein_coding_gene - - - CR45222 - CR45222 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013500 l(1)MA lethal (1) MA http://flybase.org/reports/FBgn0013500 - gene - - - l(1)MA - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265962 CR44749 - http://flybase.org/reports/FBgn0265962 non_protein_coding_gene - - - CR44749 - CR44749 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067786 anon-i176 anon-i176 http://flybase.org/reports/FBgn0067786 gene - - - "i176, anon-i176" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039339 CG5116 - http://flybase.org/reports/FBgn0039339 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006073, InterPro:IPR016496, InterPro:IPR030394 ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000027640" - cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000027640 "CG5116, Dromel_CG5116_FBtr0084877_mORF" "IPR030394:HflX-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR016496:GTPase HflX, IPR006073:GTP binding domain, IPR025121:GTPase HflX, N-terminal, IPR032305:GTP-binding protein, middle domain" CG5116 11-Aug-17 DroID_v2017_08 Drer\gtpbp6 - Cele\F46B6.4 Xtro\gtpbp6 Mmus\Gtpbp6 Hsap\GTPBP6 viable FBgn0052850 CG32850 - http://flybase.org/reports/FBgn0052850 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10056 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN001021049 zinc ion binding ; GO:0008270 | inferred from sequence model protein autoubiquitination ; GO:0051865 | inferred from sequence or structural similarity with HGNC:10056 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN001021049 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:10056 ubiquitin ligase complex ; GO:0000151 | inferred from sequence or structural similarity with HGNC:10056 "BEST:GH26713, BcDNA:RE41137, CG32850, RNF-11" "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG32850 11-Aug-17 DroID_v2017_08 "Drer\rnf126, Drer\rnf6, Drer\znrf3, Drer\rnf130, Drer\rnf111, Drer\rnf44, Drer\wu:fb39e10, Drer\rlim, Drer\pja2, Drer\rnf150a, Drer\rnf165b, Drer\si:ch211-81a5.1, Drer\rnf24, Drer\rnf11b, Drer\rnf32, Drer\si:dkey-51a16.9, Drer\rnf11a, Drer\zgc:175214, Drer\si:ch1073-392o20.1, Drer\rnf165a, Drer\rnf103, Drer\zswim2, Drer\rnf215, Drer\rnf150, Drer\rnf38, Drer\rnf115" "Scer\ASR1, Scer\YBR062C" "Cele\C01G6.4, Cele\eak-3" "Xtro\rnf44, Xtro\rnf111, Xtro\rnf11.2, Xtro\znrf3, Xtro\rnf126, Xtro\chmp3, Xtro\rnf38, Xtro\pja2, Xtro\rlim, Xtro\rnf115, Xtro\rnf24, Xtro\rnf11, Xtro\rnf181, Xtro\rnf149, Xtro\rnf32" "Mmus\Rnf181, Mmus\Rnf43, Mmus\Zswim2, Mmus\Znrf3, Mmus\Rnf24, Mmus\Rnf32, Mmus\Rnf115, Mmus\Rnf130, Mmus\Rnf126, Mmus\Rnf122, Mmus\Rnf149, Mmus\Rnf44, Mmus\Rnf38, Mmus\Rnf11, Mmus\Rnf111, Mmus\Rnf215, Mmus\Rnf165, Mmus\Rnf150, Mmus\Pja1, Mmus\Rlim, Mmus\Rnf6, Mmus\4930595M18Rik, Mmus\Pja2, Mmus\Rnf103" "Hsap\RNF32, Hsap\RNF215, Hsap\PJA1, Hsap\RNF149, Hsap\RNF181, Hsap\ZNRF3, Hsap\RNF111, Hsap\RLIM, Hsap\RNF24, Hsap\RNF43, Hsap\RNF115, Hsap\RNF165, Hsap\PJA2, Hsap\ZSWIM2, Hsap\RNF44, Hsap\RNF11, Hsap\RNF130, Hsap\RNF6, Hsap\CHMP3, Hsap\RNF38, Hsap\RNF122, Hsap\RNF103, Hsap\RNF126, Hsap\RNF150" "viable,fertile" FBgn0053758 CG33758 - http://flybase.org/reports/FBgn0053758 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33758 IPR010512:Protein of unknown function DUF1091 CG33758 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259654 B0960 - http://flybase.org/reports/FBgn0259654 gene - - - B0960 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,tarsal segment,unguis" FBgn0028879 CG15270 - http://flybase.org/reports/FBgn0028879 protein_coding_gene intracellular calcium activated chloride channel activity ; GO:0005229 | inferred from sequence or structural similarity with UniProtKB:Q9NW15 calcium activated cation channel activity ; GO:0005227 | inferred from sequence or structural similarity with HGNC:25519 chloride transport ; GO:0006821 | inferred from sequence or structural similarity with UniProtKB:Q9NW15 cation transport ; GO:0006812 | inferred from sequence or structural similarity with HGNC:25519 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:25519 "BG:DS04929.1, CG15270" "IPR007632:Anoctamin, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG15270 11-Aug-17 DroID_v2017_08 "Drer\ano10a, Drer\ano10b, Drer\ano8b, Drer\ano8a, Drer\ano5a" Scer\IST2 "Cele\anoh-1, Cele\anoh-2" "Xtro\ano8, Xtro\ano10" "Mmus\Ano4, Mmus\Ano7, Mmus\Ano10, Mmus\Ano3, Mmus\Ano1, Mmus\Ano5, Mmus\Ano8" "Hsap\ANO5, Hsap\ANO10, Hsap\ANO8, Hsap\ANO4, Hsap\ANO7, Hsap\ANO1" viable FBgn0026669 l(1)G0129 lethal (1) G0129 http://flybase.org/reports/FBgn0026669 - gene - - - l(1)G0129 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0031936 CG13794 - http://flybase.org/reports/FBgn0031936 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT neurotransmitter transport ; GO:0006836 | inferred from sequence model transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model CG13794 IPR000175:Sodium:neurotransmitter symporter CG13794 11-Aug-17 DroID_v2017_08 Drer\zgc:158225 - "Cele\snf-6, Cele\snf-10" - "Mmus\Slc6a3, Mmus\Slc6a7" "Hsap\SLC6A14, Hsap\SLC6A7" viable FBgn0047330 CG32235 - http://flybase.org/reports/FBgn0047330 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT25643, CG32235" - CG32235 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" FBgn0011083 l(1)Q41 lethal (1) Q41 http://flybase.org/reports/FBgn0011083 FBgn0010210 gene - - - l(1)Q41 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039025 Usp12-46 Ubiquitin-specific protease 12/46 http://flybase.org/reports/FBgn0039025 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:20485 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:20485 negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype inferred from genetic interaction with N inferred from genetic interaction with spdo cellular_component ; GO:0005575 | no biological data available "CG7023, Usp12-46, Q9VCT9, Usp12, Usp12/46" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG7023 11-Aug-17 DroID_v2017_08 "Drer\usp1, Drer\usp12a, Drer\usp12b, Drer\usp38, Drer\usp46" "Scer\UBP13, Scer\UBP9" Cele\usp-46 "Xtro\usp1, Xtro\usp46, Xtro\usp35, Xtro\hapln3" "Mmus\Usp38, Mmus\Usp35, Mmus\Usp1, Mmus\Usp12, Mmus\Usp46" "Hsap\USP12, Hsap\USP46, Hsap\USP1, Hsap\USP38, Hsap\USP35" viable "mesothoracic tergum,socket,eo sensory structure" FBgn0001629 l(1)dn6 lethal (1) discs normal 6 http://flybase.org/reports/FBgn0001629 - gene - - - "l(1)d.norm.-6, l(1)dn6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033871 CG13339 - http://flybase.org/reports/FBgn0033871 protein_coding_gene - - - "BcDNA:RE69336, CG13339" - CG13339 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0046886 Gr98c Gustatory receptor 98c http://flybase.org/reports/FBgn0046886 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr98A1, CG12884, Gr98B3, Gr98A2, 98B.3, GR98B.3, CG31060, Gr98c, GR98c" IPR013604:7TM chemoreceptor CG31060 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0029720 CG3009 - http://flybase.org/reports/FBgn0029720 protein_coding_gene phospholipase A2 activity ; GO:0004623 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090 phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 - CG3009 "IPR016090:Phospholipase A2 domain, IPR033113:Phospholipase A2, histidine active site" CG3009 11-Aug-17 DroID_v2017_08 "Drer\proca1, Drer\LOC101885160, Drer\zgc:123275" - - Xtro\proca1 "Mmus\Proca1, Mmus\Pla2g3" "Hsap\PLA2G3, Hsap\PROCA1" "viable,fertile" FBgn0267346 T:FK506-bp2 - http://flybase.org/reports/FBgn0267346 engineered_tag - - - T:FK506-bp2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261812 CG42754 - http://flybase.org/reports/FBgn0261812 protein_coding_gene - - - CG42754 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001120 gnu giant nuclei http://flybase.org/reports/FBgn0001120 FBgn0036453 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype negative regulation of DNA replication ; GO:0008156 | inferred from mutant phenotype egg activation ; GO:0007343 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | traceable author statement mitotic nuclear division ; GO:0007067 | traceable author statement inferred from genetic interaction with CycB regulation of mitotic cell cycle ; GO:0007346 | traceable author statement - "CG5272, Gnu, gnu" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG5272 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && O | stage S>=11 , embryonic stage | 0-1 hr " " oocyte

, organism

" "lethal,maternal effect,recessive,mitotic cell cycle defective,meiotic cell cycle defective,viable" "cleavage nucleus,maternal effect,female pronucleus | maternal effect,polar body nucleus,female,mitotic cell cycle | cleavage stage | maternal effect,cleavage stage embryo,nurse cell & nucleusmat.‘±Tub67C.THsimVP16,ovary,actin filament & nurse cellmat.‘±Tub67C.THsimVP16" FBgn0011671 musculin musculin http://flybase.org/reports/FBgn0011671 - gene - - - musculin - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259475 C464 - http://flybase.org/reports/FBgn0259475 gene - - - C464 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing hair FBgn0022974 snRNP120K snRNP120K http://flybase.org/reports/FBgn0022974 - gene - - - "120K, snRNP120K" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050115 GEFmeso Guanine nucleotide exchange factor in mesoderm http://flybase.org/reports/FBgn0050115 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from physical interaction with Cdc42 Ral GTPase binding ; GO:0017160 | inferred from direct assay imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype regulation of Cdc42 protein signal transduction ; GO:0032489 | inferred from physical interaction with Cdc42 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG5503, CG18430, CG30115, GEFmeso" "IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG30115 11-Aug-17 DroID_v2017_08 "Drer\mcf2l2, Drer\plekhg2, Drer\vav3b, Drer\spata13, Drer\arhgef4, Drer\arhgef9b, Drer\arhgef9a, Drer\LOC101885278, Drer\pex13, Drer\prex1, Drer\vav2, Drer\plekhg3" "Scer\PEX13, Scer\CDC24" "Cele\prx-13, Cele\vav-1, Cele\uig-1, Cele\tiam-1, Cele\Y37A1B.17" "Xtro\plekhg3, Xtro\plekhg1" "Mmus\Plekhg1, Mmus\Plekhg3, Mmus\Prex1, Mmus\Arhgef4, Mmus\Arhgef9, Mmus\Vav3, Mmus\Vav2, Mmus\Plekhg2, Mmus\Vav1, Mmus\Pex13, Mmus\Spata13" "Hsap\VAV2, Hsap\SPATA13, Hsap\PREX1, Hsap\PEX13, Hsap\PLEKHG2, Hsap\PLEKHG3, Hsap\VAV1, Hsap\PLEKHG1, Hsap\ARHGEF9, Hsap\ARHGEF4, Hsap\VAV3" "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "crossvein,mesoderm,supernumerary" FBgn0264460 CR43868 - http://flybase.org/reports/FBgn0264460 non_protein_coding_gene - - - CR43868 - CR43868 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265544 CR44394 - http://flybase.org/reports/FBgn0265544 pseudogene_attribute - - - CR44394 - CR44394 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051215 tRNA:Ala-AGC-2-11 transfer RNA:Alanine-AGC 2-11 http://flybase.org/reports/FBgn0051215 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna21-AlaAGC, tRNA:A:AGC:AE002708-f, CR31215, tRNA[[Ala]], chr3R.trna27-AlaAGC, tRNA-Ala-AGC-2-11, tRNA:Ala-AGC-2-11, tRNA:CR31215, GCU" - CR31215 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026194 pana pollyanna http://flybase.org/reports/FBgn0026194 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "fret, pana" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260091 2L2676 - http://flybase.org/reports/FBgn0260091 gene - - - 2L2676 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0051148 Gba1a Glucocerebrosidase 1a http://flybase.org/reports/FBgn0051148 protein_coding_gene glucosylceramidase activity ; GO:0004348 | inferred from genetic interaction with Gba1b glucosylceramide catabolic process ; GO:0006680 | inferred from biological aspect of ancestor with PANTHER:PTN001667738 adult locomotory behavior ; GO:0008344 | inferred from genetic interaction with Gba1b memory ; GO:0007613 | inferred from genetic interaction with Gba1b neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with Gba1b determination of adult lifespan ; GO:0008340 | inferred from genetic interaction with Gba1b cellular response to unfolded protein ; GO:0034620 | inferred from genetic interaction with Gba1b lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000869635 "CG10299, CT28913, anon-WO0140519.234, CG31148, dGBA1a, Gba1a" "IPR001139:Glycoside hydrolase family 30, IPR017853:Glycoside hydrolase superfamily, IPR033452:Glycosyl hydrolase family 30, beta sandwich domain, IPR033453:Glycosyl hydrolase family 30, TIM-barrel domain" CG31148 11-Aug-17 DroID_v2017_08 Drer\gba - "Cele\gba-3, Cele\gba-1, Cele\gba-2, Cele\gba-4" - Mmus\Gba Hsap\GBA "viable,visible" mesothoracic tergum FBgn0002116 l(2)cg lethal (2) with comb gap http://flybase.org/reports/FBgn0002116 - gene - - - l(2)cg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031607 CG15440 - http://flybase.org/reports/FBgn0031607 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 - - "cg15440, CG15440, Secp43" "IPR000504:RNA recognition motif domain, IPR034510:SECp43, RNA recognition motif 2" CG15440 11-Aug-17 DroID_v2017_08 "Drer\hnrnpd, Drer\rbm34, Drer\nono, Drer\hnrnpc, Drer\hnrnpabb, Drer\zgc:55733, Drer\zcrb1, Drer\tia1l, Drer\raly, Drer\cirbpa, Drer\trnau1apa, Drer\eif4h, Drer\hnrnpaba, Drer\sfpq, Drer\eif4ba, Drer\tial1, Drer\srsf10a, Drer\dazl, Drer\tia1, Drer\ncoa5, Drer\hnrnpa1b, Drer\wu:fq32h04, Drer\hnrnpa3, Drer\trnau1apb" "Scer\NOP6, Scer\MRN1, Scer\NAB6, Scer\NOP12, Scer\CWC2, Scer\NAM8, Scer\MUD1, Scer\PUB1, Scer\NGR1" "Cele\tiar-1, Cele\T07F10.3" "Xtro\rbm34, Xtro\ralyl, Xtro\trnau1ap, Xtro\dazl, Xtro\tia1, Xtro\eif4b, Xtro\hnrnpd, Xtro\hnrnpa3, Xtro\cirbp, Xtro\eif4h, Xtro\hnrnpa2b1, Xtro\sfpq, Xtro\hnrnpdl, Xtro\hnrnpa1, Xtro\hnrnpc, Xtro\raly, Xtro\hnrnpab" "Mmus\Srsf10, Mmus\Srsf12, Mmus\Boll, Mmus\Eif4b, Mmus\Slirp, Mmus\Eif4h, Mmus\Hnrnpa1, Mmus\Hnrnpa2b1, Mmus\Hnrnpa3, Mmus\Hnrnpab, Mmus\Rbm31y, Mmus\Hnrnpc, Mmus\Rbm34, Mmus\Trnau1ap, Mmus\Gm21379, Mmus\Raly, Mmus\Tia1, Mmus\Sfpq, Mmus\Tial1, Mmus\Hnrnpd, Mmus\Tra2b, Mmus\Pspc1, Mmus\Dazl, Mmus\Cirbp, Mmus\Zcrb1" "Hsap\BOLL, Hsap\DAZ2, Hsap\HNRNPA2B1, Hsap\SFPQ, Hsap\SRSF10, Hsap\HNRNPA1L2, Hsap\EIF4B, Hsap\RALYL, Hsap\RBM3, Hsap\C6orf52, Hsap\TIAL1, Hsap\DAZL, Hsap\HNRNPC, Hsap\DAZ1, Hsap\HNRNPA1, Hsap\HNRNPAB, Hsap\RALY, Hsap\HNRNPD, Hsap\TIA1, Hsap\RBM34, Hsap\DAZ3, Hsap\SLIRP, Hsap\PSPC1, Hsap\HNRNPA3, Hsap\DAZ4, Hsap\CIRBP, Hsap\TRNAU1AP, Hsap\EIF4H, Hsap\HNRNPCL1" "partially lethal - majority die,body color defective" mesothoracic tergum FBgn0001084 fy fuzzy http://flybase.org/reports/FBgn0001084 - protein_coding_gene - establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | traceable author statement - "CG13396, fy" IPR026069:Fuzzy protein CG13396 11-Aug-17 DroID_v2017_08 Drer\fuz - - Xtro\fuz Mmus\Fuz Hsap\FUZ embryonic stage -- adult stage organism

"wild-type,planar polarity defective,viable,visible,recessive" "wing hair,wing hair & 1st posterior cell,wing hair & 3rd posterior cell,wing & trichome,wing cell,macrochaeta,microchaeta & adult thorax,wing margin bristle,microchaeta & leg,bract,trichome,trichogen cell" DRSC03533 K -0.677267405 -0.128713273 -0.429033216 0.283398489 1.524777308 -0.528743578 FBgn0030228 BTBD9 BTB (POZ) domain containing 9 http://flybase.org/reports/FBgn0030228 protein_coding_gene "ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein binding, bridging ; GO:0030674 | inferred from sequence or structural similarity with PDB:3HVE" "adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype regulation of synaptic transmission, dopaminergic ; GO:0032225 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504" cytoplasm ; GO:0005737 | inferred from direct assay Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from sequence or structural similarity with PDB:3HVE SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "BTBD9, dBTBD9, CG1826" "IPR000210:BTB/POZ domain, IPR008979:Galactose-binding domain-like, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR034091:BTBD9, BACK-like domain, IPR000421:Coagulation factor 5/8 C-terminal domain" CG1826 11-Aug-17 DroID_v2017_08 Drer\btbd9 Scer\YIL001W Cele\hpo-9 "Xtro\klhl41, Xtro\btbd9" Mmus\Btbd9 "Hsap\BTBD9, Hsap\BTBD19" "viable,short lived,sleep defective,recessive,locomotor behavior defective" DRSC22371 K -0.44672001 0.1189548 -0.571569764 -0.267415836 -1.553329981 -0.269928017 FBgn0038057 CG12267 - http://flybase.org/reports/FBgn0038057 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR008806 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000310442 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR008806" DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000310442 CG12267 "IPR008806:RNA polymerase III Rpc82, C -terminal, IPR013197:RNA polymerase III subunit RPC82-related, helix-turn-helix, IPR011991:Winged helix-turn-helix DNA-binding domain" CG12267 11-Aug-17 DroID_v2017_08 Drer\polr3c Scer\RPC82 Cele\let-611 Xtro\polr3c Mmus\Polr3c Hsap\POLR3C "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264629 asthmatic asthmatic http://flybase.org/reports/FBgn0264629 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - asthmatic - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,somatic clone,terminal tracheal cell,embryonic/larval tracheal system" FBgn0000276 CecA1 Cecropin A1 http://flybase.org/reports/FBgn0000276 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay defense response to Gram-negative bacterium ; GO:0050829 | inferred from expression pattern defense response to bacterium ; GO:0042742 | traceable author statement autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern antibacterial humoral response ; GO:0019731 | inferred from expression pattern AND inferred from sequence or structural similarity antibacterial humoral response ; GO:0019731 | inferred from direct assay antibacterial humoral response ; GO:0019731 | inferred from expression pattern humoral immune response ; GO:0006959 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CecA1, Cecropin A1, Cec, CEC, CecA, cec, CG1365, cecA1, cecA, Cec A1, crpA1, DIM 25, Cec-A1" "IPR000875:Cecropin, IPR020400:Cecropin, diptera" CG1365 11-Aug-17 DroID_v2017_08 - - - - - - " pupal stage , larval stage , adult stage " " embryonic/larval hemocyte

, adult fat body

" "viable,body color defective" "adult posterior midgut epithelium,mesothoracic tergum" FBgn0011105 l(1)Q66 lethal (1) Q66 http://flybase.org/reports/FBgn0011105 FBgn0010210 gene - - - l(1)Q66 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060548 l(3)S098516a lethal (3) S098516a http://flybase.org/reports/FBgn0060548 gene - - - "0985/16, l(3)S098516a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086449 Cog8 - http://flybase.org/reports/FBgn0086449 gene - - - Cog8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263555 mir-4943 mir-4943 stem loop http://flybase.org/reports/FBgn0263555 miRNA_gene - - - "mir-4943, dme-mir-4943, CR43540" - CR43540 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015370 charon charon http://flybase.net/reports/FBgn0015370.html gene chn 11-Aug-17 DroID_v2017_08 FBgn0040605 CG14236 - http://flybase.org/reports/FBgn0040605 protein_coding_gene - - - CG14236 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000758 fs(1)A462 female sterile (1) A462 http://flybase.org/reports/FBgn0000758 - gene - - - "fs(1)462, fs(1)A462" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile soma-dependent,recessive" FBgn0011855 tRNA:Glu-CTC-3-9 transfer RNA:Glutamic acid-CTC 3-9 http://flybase.org/reports/FBgn0011855 "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052322, FBgn0060245" tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "glu-trna, AE002584.trna11-GluCTC, tRNA:E4, tRNA:E:CTC:AE002584-i, tRNA:glu4:62Ae, CR32322, tRNA:Glu, chr3L.trna11-GluCTC, tRNA:Glu-CTC-3-9, tRNA:E4:62Ae, tRNA-Glu-CTC-3-9, GAG" - CR32322 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028138 l(3)S048318 lethal (3) S048318 http://flybase.org/reports/FBgn0028138 gene - - - "0483/18, l(3)S048318" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264467 CR43875 - http://flybase.org/reports/FBgn0264467 non_protein_coding_gene - - - CR43875 - CR43875 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069249 attP:Dps2 pseudo attP recognition site Dps2 http://flybase.org/reports/FBgn0069249 region - - - attP:Dps2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267249 CR45689 - http://flybase.org/reports/FBgn0267249 non_protein_coding_gene - - - CR45689 - CR45689 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010651 MFS14 Major Facilitator Superfamily Transporter 14 http://flybase.org/reports/FBgn0010651 FBgn0034393 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from direct assay "CG15095, 8717, MFS14, l(2)08717, lethal (2) 08717, lethal(2)08717, l208717" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG15095 11-Aug-17 DroID_v2017_08 "Drer\ppt1, Drer\si:ch1073-513e17.1, Drer\slc17a9a, Drer\slc17a5, Drer\slc17a8, Drer\slc17a6a, Drer\slc17a7a, Drer\slc17a6b" "Scer\YIL166C, Scer\DAL5, Scer\THI73, Scer\TNA1" "Cele\T02B11.6, Cele\T19D12.9, Cele\vglu-3, Cele\Y15E3A.4, Cele\F10C2.7, Cele\C01B4.7, Cele\slc-17.5, Cele\C01B4.8, Cele\slc-17.4, Cele\C18H9.5, Cele\F11A5.9, Cele\eat-4, Cele\C18D1.2, Cele\slc-17.2, Cele\F41C3.2, Cele\Y19D10A.11, Cele\T22F3.11, Cele\Y19D10A.5, Cele\F56A4.12, Cele\slc-17.3, Cele\F56A4.10, Cele\R10D12.1, Cele\T28H11.8, Cele\vglu-2, Cele\M162.5, Cele\H11E01.2, Cele\T01H3.3, Cele\F44E7.7, Cele\Y4C6B.4, Cele\T27D12.1, Cele\T22F3.10, Cele\cima-1, Cele\K08C7.1, Cele\T22F3.7, Cele\C35A5.3, Cele\T19D12.10, Cele\F59A1.13, Cele\slc-17.9, Cele\Y19D10A.8, Cele\C39E9.7, Cele\D1046.4, Cele\Y51B9A.6, Cele\slc-17.8, Cele\W04C9.6, Cele\Y19D10A.4, Cele\K11G9.5, Cele\Y4C6B.3, Cele\M117.1, Cele\slc-17.1, Cele\T22F3.8" Xtro\slc17a7 "Mmus\Slc17a2, Mmus\Slc17a3, Mmus\Slc17a7, Mmus\Slc17a6, Mmus\Slc17a1, Mmus\Slc17a8, Mmus\Slc17a5, Mmus\Slc17a4" "Hsap\SLC17A8, Hsap\SLC17A1, Hsap\SLC17A7, Hsap\SLC17A2, Hsap\SLC17A6, Hsap\SLC17A3, Hsap\SLC17A4, Hsap\SLC17A5" "viable,lethal,recessive" FBgn0036188 CG7339 - http://flybase.org/reports/FBgn0036188 protein_coding_gene RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000295357 neurogenesis ; GO:0022008 | inferred from mutant phenotype transcription initiation from RNA polymerase III promoter ; GO:0006384 | inferred from biological aspect of ancestor with PANTHER:PTN000295357 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000295357 "CG7339, lincRNA.S4825" "IPR005576:RNA polymerase Rpb7, N-terminal, IPR013238:RNA polymerase III, subunit Rpc25, IPR012340:Nucleic acid-binding, OB-fold" CG7339 11-Aug-17 DroID_v2017_08 Drer\polr3h Scer\RPC25 Cele\rpc-25 Xtro\polr3h Mmus\Polr3h Hsap\POLR3H "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0035407 Asciz ASCIZ zinc finger protein http://flybase.org/reports/FBgn0035407 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype polytene chromosome interband ; GO:0005705 | inferred from direct assay spindle matrix ; GO:1990047 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Asciz, dASCIZ, CG14962, CC15, Digitor" IPR013087:Zinc finger C2H2-type CG14962 11-Aug-17 DroID_v2017_08 "Drer\znf142, Drer\im:7147486, Drer\atmin" Scer\RME1 "Cele\zfp-2, Cele\C34H4.5, Cele\pag-3" Xtro\atmin "Mmus\Zbtb41, Mmus\Atmin, Mmus\Zfp142, Mmus\Zfp574" "Hsap\ZBTB41, Hsap\ZNF142, Hsap\ATMIN, Hsap\IKZF5, Hsap\ZNF574" "visible,mitotic cell cycle defective,increased cell death,lethal - all die during first instar larval stage,viable" "wing,posterior compartment,wing disc,somatic clone" FBgn0005118 l(1)FMb lethal (1) FMb http://flybase.org/reports/FBgn0005118 - gene - - - l(1)FMb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065938 l(2)SH0120 lethal (2) SH0120 http://flybase.org/reports/FBgn0065938 gene - - - "l(2)SH0120, l(2)SH2 0120" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036778 Cyp312a1 Cyp312a1 http://flybase.org/reports/FBgn0036778 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403" - "312a1, CG5137, Cyp312a1, P450 IV" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV" CG5137 11-Aug-17 DroID_v2017_08 "Drer\cyp1c1, Drer\cyp4t8, Drer\cyp26c1, Drer\cyp46a1.3, Drer\LOC100329425, Drer\cyp46a1.4, Drer\cyp4f3, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp19a1a, Drer\cyp46a1.2, Drer\cyp1b1, Drer\cyp21a2, Drer\cyp26a1, Drer\cyp26b1, Drer\cyp1d1, Drer\cyp19a1b, Drer\cyp46a1.1, Drer\cyp20a1" "Scer\ERG11, Scer\ERG5, Scer\DIT2" "Cele\cyp-37A1, Cele\cyp-32A1, Cele\cyp-29A4, Cele\cyp-37B1, Cele\cyp-29A2, Cele\cyp-42A1, Cele\cyp-29A3, Cele\cyp-32B1, Cele\cyp-31A2, Cele\cyp-31A5, Cele\cyp-31A3" "Xtro\cyp26c1, Xtro\cyp1a1, Xtro\cyp4f2, Xtro\cyp20a1, Xtro\cyp4b1.2, Xtro\mgc108213, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\cyp19a1, Xtro\cyp4v2, Xtro\LOC100487918, Xtro\cyp26a1, Xtro\cyp4b1, Xtro\cyp26b1" "Mmus\Cyp26c1, Mmus\Cyp51, Mmus\Cyp4b1, Mmus\Cyp20a1, Mmus\Cyp4a12a, Mmus\Cyp4f15, Mmus\Cyp4a29, Mmus\Cyp4f13, Mmus\Cyp4f17, Mmus\Cyp4a10, Mmus\Cyp4a30b, Mmus\Cyp4f14, Mmus\Cyp46a1, Mmus\Cyp4a12b, Mmus\Cyp4a31, Mmus\Cyp26a1, Mmus\Cyp4a14, Mmus\Cyp4f37, Mmus\Cyp4f39, Mmus\Cyp4v3, Mmus\Cyp4x1, Mmus\Cyp26b1, Mmus\Cyp4a32, Mmus\Cyp19a1, Mmus\Cyp4f18, Mmus\Cyp4f16, Mmus\Cyp4f40" "Hsap\CYP20A1, Hsap\CYP46A1, Hsap\CYP4F2, Hsap\CYP4Z1, Hsap\CYP4X1, Hsap\CYP4A11, Hsap\CYP4A22, Hsap\CYP4F8, Hsap\CYP51A1, Hsap\CYP19A1, Hsap\CYP4V2, Hsap\CYP4F11, Hsap\CYP26B1, Hsap\CYP26C1, Hsap\CYP4F22, Hsap\CYP4F12, Hsap\CYP26A1, Hsap\CYP4B1, Hsap\CYP4F3" viable FBgn0005293 mei-2245 meiotic 2245 http://flybase.org/reports/FBgn0005293 - gene - - - "2245, mei-2245" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0040909 CG12686 - http://flybase.org/reports/FBgn0040909 protein_coding_gene - - - CG12686 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039500 CG5984 - http://flybase.org/reports/FBgn0039500 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity - - CG5984 "IPR001298:Filamin/ABP280 repeat, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR017868:Filamin/ABP280 repeat-like" CG5984 11-Aug-17 DroID_v2017_08 "Drer\flna, Drer\flnb, Drer\flnca, Drer\LOC100534866, Drer\flncb, Drer\flnbl" - Cele\fln-1 "Xtro\flnb, Xtro\flnc, Xtro\flna" "Mmus\Flnc, Mmus\Flna, Mmus\Flnb" "Hsap\FLNC, Hsap\FLNB, Hsap\FLNA" FBgn0053234 CG33234 - http://flybase.org/reports/FBgn0053234 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000628500 "CG12036, CG33234" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG33234 11-Aug-17 DroID_v2017_08 "Drer\slc22a7b.1, Drer\sv2ba, Drer\sv2a, Drer\slc22a7b.3, Drer\zmp:0000001102, Drer\slc22a13, Drer\slc22a21, Drer\LOC100334012, Drer\sv2bb, Drer\sv2c, Drer\slc22a5, Drer\LOC101884074, Drer\sv2, Drer\zgc:175176, Drer\slc22a6l, Drer\oatx, Drer\slc22a7b.2" "Scer\DTR1, Scer\YHK8, Scer\QDR1, Scer\AQR1, Scer\QDR3, Scer\TPO3, Scer\TPO1, Scer\FLR1, Scer\TPO2, Scer\GIT1, Scer\QDR2" "Cele\T12B3.2, Cele\F23F12.13, Cele\K11D9.3, Cele\F23F12.3, Cele\C44C10.3, Cele\svop-1" "Xtro\slc22a6, Xtro\sv2b" "Mmus\Slc22a20, Mmus\Slc22a28, Mmus\Slc22a14, Mmus\Slc22a22, Mmus\Slc22a26, Mmus\Sv2b, Mmus\Slc22a4, Mmus\Slc22a19, Mmus\Slc22a27, Mmus\Slc22a8, Mmus\Slc22a29, Mmus\Svop, Mmus\Slc22a16, Mmus\Slc22a6, Mmus\Slc22a2, Mmus\Slc22a23, Mmus\Slc22a30, Mmus\Sv2c, Mmus\Slc22a7, Mmus\Sv2a" "Hsap\SLC22A25, Hsap\SV2B, Hsap\SVOP, Hsap\SV2C, Hsap\SLC22A1, Hsap\SV2A, Hsap\SLC22A12, Hsap\SLC22A7, Hsap\SLC22A10, Hsap\SLC22A9, Hsap\SLC22A8, Hsap\SLC22A24, Hsap\SLC22A23, Hsap\SLC22A11, Hsap\SLC22A6, Hsap\SLC22A2" FBgn0085271 CG34242 - http://flybase.org/reports/FBgn0085271 protein_coding_gene - - - CG34242 IPR027917:Protein of unknown function DUF4538 CG34242 11-Aug-17 DroID_v2017_08 Drer\smim20 - - - Mmus\Smim20 Hsap\SMIM20 FBgn0000846 fs(1)M33 female sterile (1) M33 http://flybase.org/reports/FBgn0000846 - gene - - - fs(1)M33 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile chorion FBgn0061027 l(3)S024706b lethal (3) S024706b http://flybase.org/reports/FBgn0061027 gene - - - "0247/06, l(3)S024706b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266175 pre-mod(mdg4)-P - http://flybase.org/reports/FBgn0266175 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-P, CG44881" "IPR007588:Zinc finger, FLYWCH-type" CG44881 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014903 CG14630 - http://flybase.org/reports/FBgn0014903 FBgn0029555 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003819 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003819 - "EG:BACR7A4.9, anon-1Eb, B, CG14630" "IPR003819:TauD/TfdA-like domain, IPR007175:RNAse P, Rpr2/Rpp21 subunit, IPR010376:Domain of unknown function DUF971" CG14630 11-Aug-17 DroID_v2017_08 "Drer\tmlhe, Drer\bbox1" Scer\AIM17 "Cele\gbh-1, Cele\gbh-2" "Xtro\tmlhe, Xtro\bbox1" "Mmus\Tmlhe, Mmus\Bbox1" "Hsap\TMLHE, Hsap\BBOX1" DRSC18166 I 2.419458636 0.134205101 0.826608037 0.346478239 -0.77077799 0.093511441 FBgn0010213 Sod2 Superoxide dismutase 2 (Mn) http://flybase.org/reports/FBgn0010213 - protein_coding_gene "metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001189, InterPro:IPR019831, InterPro:IPR019832, InterPro:IPR019833 antioxidant activity ; GO:0016209 | non-traceable author statement superoxide dismutase activity ; GO:0004784 | inferred from sequence or structural similarity with UniProtKB:P04179" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001189, InterPro:IPR019831, InterPro:IPR019832, InterPro:IPR019833 heart morphogenesis ; GO:0003007 | inferred from mutant phenotype removal of superoxide radicals ; GO:0019430 | inferred from sequence or structural similarity with UniProtKB:P04179 regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype regulation of mitophagy ; GO:1903146 | inferred from genetic interaction with park reactive oxygen species metabolic process ; GO:0072593 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | traceable author statement regulation of metabolic process ; GO:0019222 | inferred from mutant phenotype paracrine signaling ; GO:0038001 | inferred from mutant phenotype" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P04179 "Sod-2, MnSOD, Mn-SOD, Mn[2+]SOD, SOD2, CG8905, Mn SOD, mnSOD, SOD, SOD-2, Sod2, MnSODII, sod2, dSOD2, Mn-SOD2, mitSOD2, Mito SOD, dSod2" "IPR001189:Manganese/iron superoxide dismutase, IPR019831:Manganese/iron superoxide dismutase, N-terminal, IPR019832:Manganese/iron superoxide dismutase, C-terminal, IPR019833:Manganese/iron superoxide dismutase, binding site" CG8905 11-Aug-17 DroID_v2017_08 Drer\sod2 "Scer\SOD2, Scer\MRP1, Scer\RSM26" "Cele\sod-3, Cele\sod-2" Xtro\sod2 Mmus\Sod2 Hsap\SOD2 "short lived,tetracycline conditional,long lived,heat sensitive,viable,fertile,dominant,chemical sensitive,recessive,stress response defective,locomotor behavior defective,behavior defective,smell perception defective,gravitaxis defective,increased cell death,lethal,some die during immature adult stage,decreased cell number,conditional,oxidative stress response defective,bang sensitive,progressive,neuroanatomy defective" "adult heart,adult brain,lamellocyte,conditional,embryonic/larval motor neuron" DRSC07554 E -0.018967043 0.145473639 -1.958978767 0.477877685 0.162888548 0.129518469 FBgn0265914 CR44703 - http://flybase.org/reports/FBgn0265914 non_protein_coding_gene - - - CR44703 - CR44703 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028995 ponderosa ponderosa http://flybase.org/reports/FBgn0028995 gene molecular_function ; GO:0003674 | no biological data available dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ponderosa - - 11-Aug-17 DroID_v2017_08 - - - - - - dendrite | dorsal | embryonic stage FBgn0001692 l(1)ESHS13 lethal (1) ESHS13 http://flybase.org/reports/FBgn0001692 - gene - - - l(1)ESHS13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004085 Ec3 Ecysone-induced RNA 3 http://flybase.org/reports/FBgn0004085 - gene - - - Ec3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043480 l(3)66EFf lethal (3) 66EFf http://flybase.org/reports/FBgn0043480 gene - - - l(3)66EFf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034183 SmydA-6 "SET and MYND domain containing, arthropod-specific, member 6" http://flybase.org/reports/FBgn0034183 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 - "SmydA-6, CG9642" IPR001214:SET domain CG9642 11-Aug-17 DroID_v2017_08 "Drer\erlin2, Drer\smyd3, Drer\smyd4, Drer\erlin1, Drer\smyd2a, Drer\smyd2b, Drer\smyd1b, Drer\smyd1a" "Scer\SET5, Scer\SET6" "Cele\set-30, Cele\set-18, Cele\erl-1, Cele\set-10" "Xtro\smyd4, Xtro\erlin2, Xtro\erlin1, Xtro\smyd5, Xtro\smyd1" "Mmus\Smyd3, Mmus\Smyd2, Mmus\Smyd4, Mmus\Smyd1, Mmus\Zmynd15, Mmus\Erlin2, Mmus\Erlin1, Mmus\Smyd5" "Hsap\SMYD1, Hsap\SMYD3, Hsap\ERLIN1, Hsap\SMYD4, Hsap\SMYD2, Hsap\SMYD5, Hsap\ZMYND15" viable FBgn0043035 l(2)42Bi lethal (2) 42Bi http://flybase.org/reports/FBgn0043035 gene - - - l(2)42Bi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052512 CG32512 - http://flybase.org/reports/FBgn0052512 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15447, CG1739, CG32512" IPR025423:Domain of unknown function DUF4149 CG32512 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-121a2.4, Drer\tmem205" Scer\YPR098C - Xtro\tmem205 Mmus\Tmem205 Hsap\TMEM205 "partially lethal - majority die,some die during pupal stage" FBgn0264857 iab-8 iab-8 non-coding RNA http://flybase.org/reports/FBgn0264857 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "iab-8, iab-8 ncRNA, iab, msa, CG31270, mpa, CR43261, miR-iab-8, iab-8ncRNA" - CR43261 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female sterile" FBgn0034136 DAT Dopamine transporter http://flybase.org/reports/FBgn0034136 protein_coding_gene cocaine binding ; GO:0019811 | inferred from direct assay dopamine transmembrane transporter activity ; GO:0005329 | inferred from direct assay dopamine:sodium symporter activity ; GO:0005330 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 circadian sleep/wake cycle ; GO:0042745 | inferred from direct assay sleep ; GO:0030431 | inferred from mutant phenotype regulation of presynaptic cytosolic calcium ion concentration ; GO:0099509 | inferred from mutant phenotype dopamine transport ; GO:0015872 | inferred from direct assay response to odorant ; GO:1990834 | inferred from mutant phenotype dopamine uptake involved in synaptic transmission ; GO:0051583 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 circadian sleep/wake cycle ; GO:0042745 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 "CG8380, fmn, DAT, dDAT, DmDAT, fumin, dat" IPR000175:Sodium:neurotransmitter symporter CG8380 11-Aug-17 DroID_v2017_08 "Drer\slc6a13, Drer\slc6a11a, Drer\si:ch211-132b12.6, Drer\slc6a16a, Drer\slc6a2, Drer\slc6a15, Drer\slc6a14, Drer\zgc:158225, Drer\slc6a6a, Drer\slc6a16b, Drer\slc6a18, Drer\slc6a5, Drer\slc6a19a.1, Drer\slc6a13, Drer\slc6a1l, Drer\si:ch211-117c9.5, Drer\slc6a13l, Drer\slc6a19a.2, Drer\si:ch211-132b12.2, Drer\slc6a4b, Drer\slc6a9, Drer\slc6a1b, Drer\slc6a8, Drer\slc6a19b, Drer\slc6a4a, Drer\slc6a6b, Drer\slc6a17, Drer\slc6a1a, Drer\si:ch211-132b12.1" - "Cele\dat-1, Cele\snf-11, Cele\snf-3, Cele\snf-6, Cele\mod-5" "Xtro\slc6a8, Xtro\slc6a12, Xtro\slc6a2, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a16, Xtro\slc6a17, Xtro\slc6a13, Xtro\slc6a5, Xtro\slc6a15, Xtro\LOC100127682, Xtro\slc6a1, Xtro\slc6a3, Xtro\slc6a19, Xtro\slc6a7, Xtro\slc6a14.2, Xtro\slc6a9" "Mmus\Slc6a9, Mmus\Slc6a17, Mmus\Slc6a12, Mmus\Slc6a3, Mmus\Slc6a5, Mmus\Slc6a14, Mmus\Slc6a16, Mmus\Slc6a2, Mmus\Slc6a15, Mmus\Slc6a13, Mmus\Slc6a4, Mmus\Slc6a19, Mmus\Slc6a8, Mmus\Slc6a1, Mmus\Slc6a21, Mmus\Slc6a11, Mmus\Slc6a7, Mmus\Slc6a6, Mmus\Slc6a20a, Mmus\Slc6a20b, Mmus\Slc6a18" "Hsap\SLC6A13, Hsap\SLC6A11, Hsap\SLC6A2, Hsap\SLC6A3, Hsap\SLC6A19, Hsap\SLC6A6, Hsap\SLC6A20, Hsap\SLC6A9, Hsap\SLC6A8, Hsap\SLC6A7, Hsap\SLC6A17, Hsap\SLC6A12, Hsap\SLC6A18, Hsap\SLC6A1, Hsap\SLC6A4, Hsap\SLC6A5, Hsap\SLC6A15, Hsap\SLC6A16, Hsap\SLC6A14" "behavior defective,hyperactive,chemical conditional,locomotor behavior defective,circadian rhythm defective,viable,fertile,sleep defective,visible" mesothoracic tergum FBgn0016072 su(w[a])::tra su(w[a])::tra http://flybase.org/reports/FBgn0016072 - engineered_fusion_gene - - - su(w[a])::tra - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046776 CR14033 - http://flybase.org/reports/FBgn0046776 pseudogene_attribute - - - "BcDNA:LD26231, BcDNA:LD26673, CR14033, CG14033" - CR14033 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02358 E 1.184358107 0.841403925 1.551278363 3.273890028 0.536744075 0.112569003 FBgn0259657 B2037 - http://flybase.org/reports/FBgn0259657 gene - - - B2037 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,proximal,scutellum" FBgn0036164 CG7543 - http://flybase.org/reports/FBgn0036164 protein_coding_gene - - - CG7543 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065285 l(2)SH2022 lethal (2) SH2022 http://flybase.org/reports/FBgn0065285 gene - - - "l(2)SH2022, l(2)SH2 2022" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029074 l(1)G0145 lethal (1) G0145 http://flybase.org/reports/FBgn0029074 gene - - - l(1)G0145 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0022893 Df31 Decondensation factor 31 http://flybase.org/reports/FBgn0022893 "FBgn0015041, FBgn0022155, FBgn0022348, FBgn0025987, FBgn0026586, FBgn0027759, FBgn0045899, FBtr0085919, FBtr0085920, FBpp0085274" protein_coding_gene histone binding ; GO:0042393 | inferred from direct assay nucleosome assembly ; GO:0006334 | inferred from direct assay chromatin organization ; GO:0006325 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay polytene chromosome ; GO:0005700 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "anon-EST:Posey126, CG2207, anon1A4, DF 31, LD04967, clone 1.46, DF31, l(2)k05815, anon-EST:fe1A4, BEST:LD04967, anon-EST:Liang-1.46, anon-WO0153538.53, Df31" - CG2207 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,recessive,long lived,wild-type,partially lethal - majority die" chromatin FBgn0260599 2L2718 - http://flybase.org/reports/FBgn0260599 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2718 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0267961 CR46241 - http://flybase.org/reports/FBgn0267961 non_protein_coding_gene - - - "CR46241, lincRNA.522" - CR46241 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027615 CG6404 - http://flybase.org/reports/FBgn0027615 - protein_coding_gene - protein insertion into membrane ; GO:0051205 | inferred from electronic annotation with InterPro:IPR001708 respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with UniProtKB:Q15070 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001708 mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity with UniProtKB:Q15070 "BcDNA:GH02220, CG6404, OXA1" "IPR001708:Membrane insertase OXA1/ALB3/YidC, IPR028055:Membrane insertase YidC/Oxa1, C-terminal" CG6404 11-Aug-17 DroID_v2017_08 "Drer\oxa1l, Drer\cox18" "Scer\OXA1, Scer\COX18" "Cele\Y55F3AR.1, Cele\oxa-1" "Xtro\oxa1l, Xtro\cox18" "Mmus\Cox18, Mmus\Oxa1l" "Hsap\COX18, Hsap\OXA1L" DRSC09672 K 0.320060997 -0.359578719 -0.163800958 0.243142942 0.603791233 1.713725377 FBgn0011748 anon-M-SAR anonymous M/SAR sequence http://flybase.org/reports/FBgn0011748 - repeat_region - - - "centromere; lamin. centromeric beta-heterochromatin sequence, anon-M/SAR, anon-M-SAR" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266990 CR45441 - http://flybase.org/reports/FBgn0266990 non_protein_coding_gene - - - CR45441 - CR45441 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050073 Obp50b Odorant-binding protein 50b http://flybase.org/reports/FBgn0050073 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG30073, CG13940, Obp50b, DmelObp50b" IPR006170:Pheromone/general odorant binding protein CG30073 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065477 l(2)SH1297 lethal (2) SH1297 http://flybase.org/reports/FBgn0065477 gene - - - "l(2)SH1297, l(2)SH2 1297" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034417 CG15117 - http://flybase.org/reports/FBgn0034417 protein_coding_gene beta-glucuronidase activity ; GO:0004566 | inferred from biological aspect of ancestor with PANTHER:PTN000007257 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern carbohydrate metabolic process ; GO:0005975 | inferred from biological aspect of ancestor with PANTHER:PTN000007197 extracellular space ; GO:0005615 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000007197 CG15117 "IPR006101:Glycoside hydrolase, family 2, IPR006102:Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich, IPR006103:Glycoside hydrolase family 2, catalytic domain, IPR006104:Glycosyl hydrolases family 2, sugar binding domain, IPR008979:Galactose-binding domain-like, IPR017853:Glycoside hydrolase superfamily, IPR013783:Immunoglobulin-like fold, IPR023230:Glycoside hydrolase, family 2, conserved site, IPR023232:Glycoside hydrolase, family 2, active site" CG15117 11-Aug-17 DroID_v2017_08 Drer\gusb - Cele\Y105E8B.9 Xtro\gusb Mmus\Gusb "Hsap\GUSB, Hsap\LOC100653061" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC06539 I -1.963157371 -1.045937417 -0.339340485 0.770838827 -0.984755744 -1.248662544 FBgn0033788 CG13323 - http://flybase.org/reports/FBgn0033788 protein_coding_gene - - - "FBgn0033788, CG13323" IPR031734:Transcription activator MBF2 CG13323 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264368 CR43820 - http://flybase.org/reports/FBgn0264368 non_protein_coding_gene - - - CR43820 - CR43820 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067328 3N5 3N5 http://flybase.org/reports/FBgn0067328 gene molecular_function ; GO:0003674 | no biological data available wing disc development ; GO:0035220 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3N5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,posterior compartment,somatic clone" FBgn0030629 CG9123 - http://flybase.org/reports/FBgn0030629 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with MGI:MGI:1915333 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with MGI:MGI:1915333 CG9123 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG9123 11-Aug-17 DroID_v2017_08 "Drer\pak1ip1, Drer\wdr55" "Scer\JIP5, Scer\MAK11" Cele\Y44F5A.1 Xtro\pak1ip1 "Mmus\Pak1ip1, Mmus\Wdr55" "Hsap\WDR55, Hsap\PAK1IP1" viable FBgn0086058 snoRNA:Me18S-G1189 - http://flybase.org/reports/FBgn0086058 snoRNA_gene - - - "snoRNA:Me18S-G1189, Me18S-Gm1189, CR34687" - CR34687 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027584 CG4757 - http://flybase.org/reports/FBgn0027584 - protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "GH05702, BcDNA:GH05741, CG4757, GH05741" "IPR002018:Carboxylesterase, type B, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG4757 11-Aug-17 DroID_v2017_08 "Drer\nlgn3b, Drer\si:ch211-93f2.1, Drer\ces3, Drer\cell, Drer\nlgn2b, Drer\nlgn2a, Drer\nlgn3a, Drer\cel.1, Drer\nlgn4b, Drer\nlgn4a, Drer\ces2, Drer\nlgn1" - "Cele\T28C12.5, Cele\nlg-1, Cele\Y71H2AM.13, Cele\K11G9.1, Cele\B0238.1, Cele\F15A8.6, Cele\ges-1, Cele\T28C12.4, Cele\R173.3, Cele\F56C11.6, Cele\K11G9.2, Cele\T07H6.1, Cele\F07C4.12" "Xtro\ces2, Xtro\nlgn4x, Xtro\ces3, Xtro\cel, Xtro\nlgn2, Xtro\nlgn3, Xtro\LOC100494782" "Mmus\Ces2e, Mmus\Ces1h, Mmus\Ces3b, Mmus\Cel, Mmus\Nlgn3, Mmus\Ces4a, Mmus\Ces5a, Mmus\Ces2c, Mmus\Ces3a, Mmus\Nlgn1, Mmus\Ces2g, Mmus\Ces1f, Mmus\Ces1b, Mmus\Ces2f, Mmus\Ces2h, Mmus\Nlgn2, Mmus\Ces2a, Mmus\Ces1e, Mmus\Ces1g, Mmus\Ces1d, Mmus\Ces2b, Mmus\Ces1c" "Hsap\CES3, Hsap\NLGN4Y, Hsap\NLGN2, Hsap\CEL, Hsap\NLGN4X, Hsap\CES1, Hsap\NLGN3, Hsap\CES4A, Hsap\CES5A, Hsap\CES2, Hsap\NLGN1" "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0063389 snoRNA:Me18S-G1620 - http://flybase.org/reports/FBgn0063389 snoRNA_gene - - - "U25snoRNA, snoRNA:U25, CR32874, snoRNA:Me18S-G1620, Me18S-G1620(U25), snoRNA:U25:30E, DmSnR56, Dm_18S.007" - CR32874 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267024 CR45468 - http://flybase.org/reports/FBgn0267024 non_protein_coding_gene - - - CR45468 - CR45468 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060404 l(3)S131010 lethal (3) S131010 http://flybase.org/reports/FBgn0060404 gene - - - "1310/10, l(3)S131010" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0013457 fs(2)neo5 fs(2)neo5 http://flybase.org/reports/FBgn0013457 - gene - - - fs(2)neo5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal,maternal effect" FBgn0259973 Sfp79B Seminal fluid protein 79 http://flybase.org/reports/FBgn0259973 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp79B, CG42483" - CG42483 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267763 CR46094 - http://flybase.org/reports/FBgn0267763 non_protein_coding_gene - - - CR46094 - CR46094 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033799 GLaz Glial Lazarillo http://flybase.org/reports/FBgn0033799 protein_coding_gene - cellular response to oxidative stress ; GO:0034599 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype lipid catabolic process ; GO:0016042 | inferred from genetic interaction with fh cellular response to oxidative stress ; GO:0034599 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "GLaz, CG4604, DGLaz" "IPR000566:Lipocalin/cytosolic fatty-acid binding domain, IPR012674:Calycin, IPR022271:Lipocalin, ApoD type" CG4604 11-Aug-17 DroID_v2017_08 "Drer\apoda.2, Drer\apoda.1, Drer\apodb" - Cele\lpr-4 - Mmus\Apod Hsap\APOD "viable,fertile,stress response defective,short lived,locomotor behavior defective,increased cell death,chemical sensitive,long lived,heat sensitive,hyperactive" "adult brain,adult nervous system,adult fat body" FBgn0040388 boi brother of ihog http://flybase.org/reports/FBgn0040388 protein_coding_gene hedgehog family protein binding ; GO:0097108 | inferred from electronic annotation with InterPro:IPR032988 cuticle pattern formation ; GO:0035017 | inferred from genetic interaction with ihog wing disc pattern formation ; GO:0035222 | inferred from genetic interaction with ihog smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from genetic interaction with ihog regulation of smoothened signaling pathway ; GO:0008589 | inferred from genetic interaction with ihog positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with Dl imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from genetic interaction with ihog integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR032988 cell surface ; GO:0009986 | colocalizes_with inferred from direct assay "CT23737, EG:BACH59J11.2, CG7894, CG13756, CT33235, boi, CG32796, Boi" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR032988:Interference hedgehog" CG32796 11-Aug-17 DroID_v2017_08 "Drer\boc, Drer\cdon" - - "Xtro\cdon, Xtro\boc" "Mmus\Cdon, Mmus\Boc" "Hsap\BOC, Hsap\CDON" "viable,fertile,hyperplasia,visible" "follicle stem cell,wing vein,ectopic,wing blade,interfollicle cell,follicle cell" FBgn0053632 CG33632 - http://flybase.org/reports/FBgn0053632 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR33632, CG33632" IPR010512:Protein of unknown function DUF1091 CG33632 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039240 CG3744 - http://flybase.org/reports/FBgn0039240 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR001375 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001375, InterPro:IPR002469" - CG3744 "IPR029058:Alpha/Beta hydrolase fold, IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR002469:Dipeptidylpeptidase IV, N-terminal domain" CG3744 11-Aug-17 DroID_v2017_08 Drer\dpp9 "Scer\DAP2, Scer\STE13" "Cele\dpf-2, Cele\dpf-1, Cele\dpf-3" "Xtro\dpp9, Xtro\dpp8" "Mmus\Dpp8, Mmus\Dpp9" "Hsap\DPP9, Hsap\DPP8" "viable,fertile" FBgn0083970 CG34134 - http://flybase.org/reports/FBgn0083970 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG8475, CG34134" - CG34134 11-Aug-17 DroID_v2017_08 "Drer\phkb, Drer\phka1a, Drer\phka1b, Drer\phka2" - - "Xtro\phkb, Xtro\phka2, Xtro\LOC100498239" "Mmus\Phkb, Mmus\Phka2, Mmus\Phka1" "Hsap\PHKA2, Hsap\PHKB, Hsap\PHKA1" FBgn0263442 CR43465 - http://flybase.org/reports/FBgn0263442 non_protein_coding_gene - - - CR43465 - CR43465 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259635 B0426 - http://flybase.org/reports/FBgn0259635 gene - - - B0426 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" proboscis FBgn0031263 Tspo Translocator protein http://flybase.org/reports/FBgn0031263 protein_coding_gene - regulation of oxidative phosphorylation ; GO:0002082 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004307 mitochondrial outer membrane ; GO:0005741 | inferred from direct assay mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity with UniProtKB:P30536 "anon-EST:Posey116, CG2789, Tspo, dTSPO, tspo" IPR004307:TspO/MBR-related protein CG2789 11-Aug-17 DroID_v2017_08 Drer\tspo - Cele\C41G7.9 Xtro\tspo "Mmus\Tspo, Mmus\Tspo2" "Hsap\TSPO2, Hsap\TSPO" viable FBgn0025476 pogo\T pogo transposase http://flybase.org/reports/FBgn0025476 - transposable_element_gene - - - pogo\T - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043581 MESK1 Misexpression Suppressor of KDN 1 http://flybase.org/reports/FBgn0043581 gene - positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with ksr inferred from genetic interaction with Ras85D - MESK1 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003359 sesA stress-sensitive A http://flybase.org/reports/FBgn0003359 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sesA - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,bang sensitive,flight defective,behavior defective" FBgn0036117 CG6321 - http://flybase.org/reports/FBgn0036117 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR015421, InterPro:IPR015422 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839" biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004839 - CG6321 "IPR004839:Aminotransferase, class I/classII, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase" CG6321 11-Aug-17 DroID_v2017_08 Drer\aadat "Scer\ARO9, Scer\YER152C, Scer\ARO8" - Xtro\aadat Mmus\Aadat Hsap\AADAT "viable,fertile" FBgn0262961 CG43272 - http://flybase.org/reports/FBgn0262961 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43272, lincRNA.337" - CG43272 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051824 CR31824 - http://flybase.org/reports/FBgn0051824 pseudogene_attribute - - - "CG18629, CR31824, CG31824" - CR31824 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034943 Fmo-1 Flavin-containing monooxygenase 1 http://flybase.org/reports/FBgn0034943 protein_coding_gene "N,N-dimethylaniline monooxygenase activity ; GO:0004499 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946 NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946 monooxygenase activity ; GO:0004497 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946, InterPro:IPR023753" intracellular membrane-bounded organelle ; GO:0043231 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "DmFMO-1, FMO-1, CG3006, Fmo-1" "IPR000960:Flavin monooxygenase FMO, IPR020946:Flavin monooxygenase-like, IPR023753:FAD/NAD(P)-binding domain" CG3006 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-239i20.4, Drer\LOC793236, Drer\si:dkey-239i20.2, Drer\fmo5, Drer\foxred2, Drer\zgc:77439" Scer\FMO1 "Cele\fmo-3, Cele\fmo-5, Cele\fmo-1, Cele\fmo-2, Cele\fmo-4, Cele\C46H11.2, Cele\C01H6.4" "Xtro\fmo1, Xtro\LOC100490281, Xtro\foxred2, Xtro\fmo5, Xtro\fmo2, Xtro\fmo3" "Mmus\Fmo9, Mmus\Fmo2, Mmus\Foxred2, Mmus\Fmo1, Mmus\Fmo5, Mmus\Fmo6, Mmus\Fmo3, Mmus\Gm4847, Mmus\Gm4846, Mmus\Fmo4" "Hsap\FOXRED2, Hsap\FMO5, Hsap\FMO4, Hsap\FMO1, Hsap\FMO3, Hsap\FMO2" "partially lethal - majority die,some die during pupal stage" FBgn0051773 CG31773 - http://flybase.org/reports/FBgn0051773 protein_coding_gene "tetrahydrofolylpolyglutamate synthase activity ; GO:0004326 | inferred from electronic annotation with InterPro:IPR001645, InterPro:IPR023600 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001645, InterPro:IPR013221, InterPro:IPR023600" "folic acid-containing compound biosynthetic process ; GO:0009396 | inferred from electronic annotation with InterPro:IPR001645, InterPro:IPR023600" - "CG3390, CG31773" "IPR001645:Folylpolyglutamate synthetase, IPR013221:Mur ligase, central, IPR023600:Folylpolyglutamate synthase, eukaryota" CG31773 11-Aug-17 DroID_v2017_08 "Drer\nphs1, Drer\fpgs" "Scer\RMA1, Scer\FOL3, Scer\MET7" Cele\F25B5.6 "Xtro\fpgs, Xtro\nphs1" "Mmus\Fpgs, Mmus\Nphs1" "Hsap\NPHS1, Hsap\FPGS" DRSC00600 IK 1.751746241 0.045667974 0.791412586 0.738587127 0.297718222 1.563776233 FBgn0083093 curta curta http://flybase.org/reports/FBgn0083093 gene - - - curta - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050268 CG30268 - http://flybase.org/reports/FBgn0050268 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 - "CG13520, CG30268" "IPR032151:Cilia- and flagella-associated protein 61, N-terminal domain, IPR023753:FAD/NAD(P)-binding domain" CG30268 11-Aug-17 DroID_v2017_08 - - - Xtro\cfap61 Mmus\Cfap61 Hsap\CFAP61 viable FBgn0020585 anon-57Cl anon-57Cl http://flybase.org/reports/FBgn0020585 - gene - - - anon-57Cl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037215 beta-Man beta-Mannosidase http://flybase.org/reports/FBgn0037215 protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR006102, InterPro:IPR013812" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006102, InterPro:IPR013781, InterPro:IPR013812" - "CG12583, CG12582, beta-Man" "IPR008979:Galactose-binding domain-like, IPR006102:Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich, IPR017853:Glycoside hydrolase superfamily, IPR013783:Immunoglobulin-like fold" CG12582 11-Aug-17 DroID_v2017_08 Drer\manba - Cele\C33G3.4 Xtro\manba Mmus\Manba Hsap\MANBA viable FBgn0053368 5SrRNA:CR33368 5SrRNA:CR33368 http://flybase.org/reports/FBgn0053368 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33368, 5SrRNA:CR33368" - CR33368 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020426 HLH44A HLH44A http://flybase.org/reports/FBgn0020426 - gene - - - "44A, HLH44A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283531 Duox Dual oxidase http://flybase.org/reports/FBgn0283531 protein_coding_gene NAD(P)H oxidase activity ; GO:0016174 | inferred from electronic annotation with InterPro:IPR029595 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from direct assay "hydrogen peroxide biosynthetic process ; GO:0050665 | inferred from electronic annotation with InterPro:IPR029595 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255, InterPro:IPR013112, InterPro:IPR013121, InterPro:IPR017927, InterPro:IPR017938 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype reactive oxygen species metabolic process ; GO:0072593 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype mucosal immune response ; GO:0002385 | inferred from mutant phenotype response to cAMP ; GO:0051591 | inferred from sequence or structural similarity with UniProtKB:Q9NRD8 adult chitin-based cuticle development ; GO:0008365 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype cytokine-mediated signaling pathway ; GO:0019221 | inferred from sequence or structural similarity with UniProtKB:Q9NRD9 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from sequence or structural similarity with UniProtKB:Q9NRD9" endomembrane system ; GO:0012505 | inferred from direct assay "Duox, DUOX, duox, Cy, l(2)23Bb, dDuox, CG3131, dduox" "IPR029595:Dual oxidase 1/Duox, IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR010255:Haem peroxidase, IPR011992:EF-hand domain pair, IPR013112:FAD-binding 8, IPR013121:Ferric reductase, NAD binding domain, IPR013130:Ferric reductase transmembrane component-like domain, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel, IPR019791:Haem peroxidase, animal" CG3131 11-Aug-17 DroID_v2017_08 "Drer\duox, Drer\nox5, Drer\nox1, Drer\cybb" "Scer\FRE4, Scer\FRE5, Scer\FRE6, Scer\FRE2, Scer\FRE8, Scer\AIM14, Scer\FRE3, Scer\FRE7, Scer\FRE1" "Cele\bli-3, Cele\duox-2" "Xtro\nox1, Xtro\cybb, Xtro\nox5, Xtro\duox1, Xtro\duox2" "Mmus\Cybb, Mmus\Duox2, Mmus\Nox3, Mmus\Nox1, Mmus\Nox4, Mmus\Duox1" "Hsap\CYBB, Hsap\NOX5, Hsap\DUOX2, Hsap\NOX4, Hsap\NOX3, Hsap\NOX1, Hsap\DUOX1" "lethal,wild-type" wing FBgn0266170 pre-mod(mdg4)-C - http://flybase.org/reports/FBgn0266170 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-C, CG44876" IPR018379:BEN domain CG44876 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026577 CG8677 - http://flybase.org/reports/FBgn0026577 "FBgn0032936, FBgn0046270" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 "heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q96T23" RSF complex ; GO:0031213 | inferred from physical interaction with Iswi nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q96T23 polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "LD14959, BEST:LD14959, BEST:LD19244, CG8677, dRsf-1, rsf-1" "IPR001965:Zinc finger, PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR011011:Zinc finger, FYVE/PHD-type, IPR019787:Zinc finger, PHD-finger, IPR018501:DDT domain" CG8677 11-Aug-17 DroID_v2017_08 "Drer\rsf1a, Drer\rsf1b.1" - - Xtro\rsf1 Mmus\Rsf1 "Hsap\RSF1, Hsap\CECR2" "long lived,partially lethal - majority die,lethal,viable,fertile,suppressor of variegation,dominant" DRSC21844 IE -0.269192362 2.43078016 1.203768388 1.516851112 -0.347434054 -0.989099814 FBgn0044451 EP682 EP682 http://flybase.org/reports/FBgn0044451 gene - - - EP682 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0040076 primo-2 primo-2 http://flybase.org/reports/FBgn0040076 protein_coding_gene non-membrane spanning protein tyrosine phosphatase activity ; GO:0004726 | inferred from electronic annotation with InterPro:IPR002115 acid phosphatase activity ; GO:0003993 | inferred from electronic annotation with InterPro:IPR002115 protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from direct assay protein dephosphorylation ; GO:0006470 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:122 cytoplasm ; GO:0005737 | non-traceable author statement "LMW-PTP, CG9599, primo, CG31311, CG33747, primo-2, Primo-2, BEO2" "IPR002115:Protein-tyrosine phosphatase, low molecular weight, mammalian, IPR017867:Protein-tyrosine phosphatase, low molecular weight, IPR023485:Phosphotyrosine protein phosphatase I superfamily" CG33747 11-Aug-17 DroID_v2017_08 Drer\acp1 Scer\LTP1 Cele\Y94H6A.7 Xtro\acp1 Mmus\Acp1 Hsap\ACP1 " embryonic stage , adult stage " " neuron &&of ventral nerve cord

, neuron &&of ventral nerve cord

, embryonic head

, embryonic epidermis | vicinity of

, embryonic/larval digestive system | restricted

" "viable,fertile" FBgn0060479 l(3)S111105 lethal (3) S111105 http://flybase.org/reports/FBgn0060479 gene - - - "1111/05, l(3)S111105" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0047199 CG31517 - http://flybase.org/reports/FBgn0047199 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:LD34214, CG31517" - CG31517 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" FBgn0031901 CG13785 - http://flybase.org/reports/FBgn0031901 protein_coding_gene - - - CG13785 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC02288 K -0.180250639 -0.230306034 -0.41107337 0.3600402 -1.696993814 -0.554800955 FBgn0026174 SkpD SKP1-related D http://flybase.org/reports/FBgn0026174 "FBgn0031072, FBgn0047345" protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000002736 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with SGD:S000002736 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with SGD:S000002736 "CG12700, dskpD, BcDNA:AT18217, Skp, SkpD, skpD" "IPR011333:SKP1/BTB/POZ domain, IPR001232:S-phase kinase-associated protein 1-like, IPR016072:SKP1 component, dimerisation, IPR016073:SKP1 component, POZ domain, IPR016897:S-phase kinase-associated protein 1" CG12700 11-Aug-17 DroID_v2017_08 Drer\skp1 Scer\SKP1 "Cele\skr-18, Cele\skr-20, Cele\skr-15, Cele\skr-5, Cele\skr-9, Cele\skr-7, Cele\skr-1, Cele\skr-10, Cele\skr-14, Cele\skr-13, Cele\skr-12, Cele\skr-21, Cele\skr-6, Cele\skr-16, Cele\skr-2, Cele\skr-3, Cele\skr-4, Cele\skr-19, Cele\skr-17, Cele\skr-8" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0023135 WppH White prepupal locus H http://flybase.org/reports/FBgn0023135 - gene - - - "9, 36, 22B, WppH" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050251 tRNA:His-GTG-1-3 transfer RNA:Histidine-GTG 1-3 http://flybase.org/reports/FBgn0050251 tRNA_gene CAC codon-amino acid adaptor activity ; GO:0033426 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033426 cytosol ; GO:0005829 | inferred by curator from GO:0033426 "AE002787.trna19-HisGTG, tRNA:H:GTG:AE002787-b, CR30251, tRNA[His], chr2R.trna78-HisGTG, tRNA-His-GTG-1-3, tRNA:His-GTG-1-3, tRNA:CR30251, CAC" - CR30251 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028644 beat-Ic beaten path Ic http://flybase.org/reports/FBgn0028644 protein_coding_gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype defasciculation of motor neuron axon ; GO:0007415 | inferred from genetic interaction with beat-Ia heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from genetic interaction with beat-Ia integral component of plasma membrane ; GO:0005887 | inferred from sequence model "beat-C, beat Ic, CT15531, BG:DS00913.1, CG4838, beat-Ic, Beat-Ic" "IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold" CG4838 11-Aug-17 DroID_v2017_08 "Drer\f11r.2, Drer\jam2b" - - - - "Hsap\CADM2, Hsap\F11R" "lethal,lethal - all die before end of pupal stage,some die during pupal stage" "intersegmental nerve,transverse nerve,RP3 motor neuron,RP1 motor neuron" DRSC03491 I -0.689103294 -1.766771426 -1.232159393 -0.915894067 0.44087451 -0.574603779 FBgn0264829 CG44037 - http://flybase.org/reports/FBgn0264829 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44037 - CG44037 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067096 H84 H84 http://flybase.org/reports/FBgn0067096 gene - - - H84 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable" FBgn0260436 CG42531 - http://flybase.org/reports/FBgn0260436 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42531 - CG42531 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067810 anon-N1 anon-N1 http://flybase.org/reports/FBgn0067810 gene - - - "N1, anon-N1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062978 CG31808 - http://flybase.org/reports/FBgn0062978 protein_coding_gene - - - "CG31808, RE70695, BcDNA:RE70695, MRE33, CR31808" - CG31808 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000915 fs(1)ne1 female sterile (1) no eggs 1 http://flybase.org/reports/FBgn0000915 - gene - - - "ne1, fs(1)ne[1], fs(1)ne1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,female sterile soma-dependent" "oocyte,endochorion,stage S10A oocyte,stage S10B oocyte,dorsal appendage,chorion" FBgn0036768 CG7402 - http://flybase.org/reports/FBgn0036768 protein_coding_gene sulfuric ester hydrolase activity ; GO:0008484 | inferred from electronic annotation with InterPro:IPR000917 "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850" - CG7402 "IPR000917:Sulfatase, N-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site" CG7402 11-Aug-17 DroID_v2017_08 "Drer\arsb, Drer\arsia, Drer\ids, Drer\sgsh, Drer\galns, Drer\LOC563783, Drer\LOC101884179, Drer\arsh, Drer\LOC559800, Drer\arsa, Drer\si:dkey-174i8.1, Drer\arsg" - Cele\sul-3 "Xtro\arsb, Xtro\arsd, Xtro\arsi, Xtro\arsj, Xtro\arsa.1, Xtro\arsk, Xtro\sgsh, Xtro\arsh, Xtro\ids, Xtro\sts" "Mmus\Arsj, Mmus\Sgsh, Mmus\Arsi, Mmus\Arsa, Mmus\Arsg, Mmus\Arsb, Mmus\Ids, Mmus\Galns" "Hsap\STS, Hsap\ARSF, Hsap\GALNS, Hsap\SGSH, Hsap\ARSG, Hsap\IDS, Hsap\ARSB, Hsap\ARSJ, Hsap\ARSE, Hsap\ARSA, Hsap\ARSI, Hsap\ARSD, Hsap\ARSH" "viable,fertile" FBgn0259255 EP-469.2 - http://flybase.org/reports/FBgn0259255 gene - - - EP-469.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta,ectopic" FBgn0051602 tRNA:Asp-GTC-1-6 transfer RNA:Aspartic acid-GTC 1-6 http://flybase.org/reports/FBgn0051602 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "Asp-tRNA, AE002690.trna6-AspGTC, tRNA:asp2:29E, tRNA:D2:29E, tRNA:D:GTC:AE002690-b, CR31602, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna15-AspGTC, tRNA:Asp-GTC-1-6, tRNA:CR31602, tRNA-Asp-GTC-1-6, GAC" - CR31602 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005217 l(3)ET8 lethal Elaine Tasaka 8 http://flybase.org/reports/FBgn0005217 - gene - - - l(3)ET8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" FBgn0083017 snoRNA:Psi18S-841c snoRNA:Psi18S-841c http://flybase.org/reports/FBgn0083017 snoRNA_gene - - - "snoRNA:Psi18S-841c, Psi18S-841c, psi18S-841c, CR34553, chr2R:16838224..16838314" - CR34553 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037382 Hpr1 Hpr1 http://flybase.org/reports/FBgn0037382 protein_coding_gene - signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000488 mRNA export from nucleus in response to heat stress ; GO:0031990 | inferred from mutant phenotype "protein complex ; GO:0043234 | inferred from physical interaction with thoc5, thoc7 THO complex ; GO:0000347 | inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:19070 nucleus ; GO:0005634 | inferred from direct assay" "CG2031, Hpr1, HPR1, Thoc1" "IPR000488:Death domain, IPR011029:Death-like domain, IPR021861:THO complex, subunit THOC1" CG2031 11-Aug-17 DroID_v2017_08 "Drer\thoc1, Drer\si:dkeyp-97b10.3, Drer\LOC103911624" - Cele\thoc-1 Xtro\thoc1 Mmus\Thoc1 Hsap\THOC1 viable DRSC12296 I 1.628419054 0.724526984 -0.937161093 -0.094311899 0.863421026 0.11575848 FBgn0267291 CR45727 - http://flybase.org/reports/FBgn0267291 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR45727 - CR45727 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015727 Est-F Est-F http://flybase.org/reports/FBgn0015727 - gene - - - "Est-Fs, Est-F" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046668 anon-38C.29 anon-38C.29 http://flybase.org/reports/FBgn0046668 gene - - - "38C.29, anon-38C.29" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014314 l(3)ry114 lethal (3) ry114 http://flybase.org/reports/FBgn0014314 - gene - - - l(3)ry114 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065325 l(2)SH1898 lethal (2) SH1898 http://flybase.org/reports/FBgn0065325 gene - - - "l(2)SH1898, l(2)SH2 1898" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031626 CG15631 - http://flybase.org/reports/FBgn0031626 protein_coding_gene - - - CG15631 - CG15631 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0261553 CG42671 - http://flybase.org/reports/FBgn0261553 protein_coding_gene - - - "CG42671, CG18490, CG34240" - CG42671 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065507 l(2)SH1185 lethal (2) SH1185 http://flybase.org/reports/FBgn0065507 gene - - - l(2)SH1185 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040993 CG17325 - http://flybase.org/reports/FBgn0040993 protein_coding_gene - - - "BcDNA:RH02271, CG17325, Dromel_CG17325_FBtr0081102_mORF" - CG17325 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263314 CG43400 - http://flybase.org/reports/FBgn0263314 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43400, lincRNA.75" - CG43400 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030395 Mks1 "Meckel syndrome, type 1" http://flybase.org/reports/FBgn0030395 protein_coding_gene - ciliary transition zone assembly ; GO:1905349 | inferred from mutant phenotype axoneme assembly ; GO:0035082 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype ciliary transition zone ; GO:0035869 | inferred from direct assay MKS complex ; GO:0036038 | inferred from sequence or structural similarity with MGI:MGI:3584243 "CG15730, Mks1, dMks1" IPR010796:B9 domain CG15730 11-Aug-17 DroID_v2017_08 Drer\mks1 - Cele\mks-1 Xtro\mks1 Mmus\Mks1 Hsap\MKS1 "viable,planar polarity defective,visible" "ommatidium,wing hair,supernumerary,wing blade" FBgn0053094 Synd Syndapin http://flybase.org/reports/FBgn0053094 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with scra phospholipid binding ; GO:0005543 | inferred from sequence model lipid binding ; GO:0008289 | inferred from direct assay synaptic vesicle endocytosis ; GO:0048488 | non-traceable author statement membrane organization ; GO:0061024 | inferred from direct assay positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype cleavage furrow ingression ; GO:0036090 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype spindle assembly involved in male meiosis ; GO:0007053 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from biological aspect of ancestor with PANTHER:PTN000860688 postsynaptic membrane ; GO:0045211 | inferred from direct assay subsynaptic reticulum ; GO:0071212 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000860688 cleavage furrow ; GO:0032154 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay "CG15694, D-Synd, CG33094, Synd, synd" "IPR001060:FCH domain, IPR001452:SH3 domain, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR031160:F-BAR domain" CG33094 11-Aug-17 DroID_v2017_08 "Drer\pacsin1a, Drer\si:ch211-51c14.1, Drer\zgc:91999, Drer\arfgap2, Drer\trip10a, Drer\itsn1, Drer\itsn2b, Drer\arfgap3, Drer\pacsin3, Drer\sh3d19, Drer\pacsin2, Drer\itsn2a, Drer\pacsin1b" "Scer\BZZ1, Scer\LSB3, Scer\HOF1, Scer\LSB1, Scer\YSC84, Scer\SYP1" "Cele\B0303.7, Cele\itsn-1, Cele\F07F6.4, Cele\sdpn-1, Cele\toca-1" "Xtro\pacsin2, Xtro\MGC147475, Xtro\pacsin1, Xtro\pacsin3, Xtro\fnbp1l, Xtro\arfgap2" "Mmus\Sh3d19, Mmus\Pacsin2, Mmus\Arfgap2, Mmus\Sh3yl1, Mmus\Itsn1, Mmus\Pacsin1, Mmus\Fnbp1, Mmus\Pacsin3, Mmus\Arfgap3, Mmus\Trip10, Mmus\Fnbp1l, Mmus\Itsn2" "Hsap\SH3D19, Hsap\ARFGAP3, Hsap\ITSN2, Hsap\SH3YL1, Hsap\PACSIN1, Hsap\ARFGAP2, Hsap\PACSIN2, Hsap\ITSN1, Hsap\PACSIN3, Hsap\FNBP1L, Hsap\FNBP1, Hsap\FCHSD1, Hsap\GRAP2, Hsap\TRIP10" "lethal - all die before end of pupal stage,some die during pupal stage,viable,majority die during third instar larval stage,cytokinesis defective,meiotic cell cycle defective,body color defective" "subsynaptic reticulum | third instar larval stageMef2.PR,postsynaptic membrane | third instar larval stageMef2.PR,subsynaptic reticulum | third instar larval stagetub.PU,onion stage spermatid,spermatocyte,spindle midzoneBSC43),contractile ringBSC43),cleavage furrowBSC43),meiotic spindleBSC43),mesothoracic tergum" FBgn0259403 C747 - http://flybase.org/reports/FBgn0259403 gene - - - C747 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0060582 l(3)S094615b lethal (3) S094615b http://flybase.org/reports/FBgn0060582 gene - - - "0946/15, l(3)S094615b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083236 EP364 EP364 http://flybase.org/reports/FBgn0083236 gene - - - EP364 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259998 CG17571 - http://flybase.org/reports/FBgn0259998 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "CG17571, anon-38C.22, SP83, 38C.22" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG17571 11-Aug-17 DroID_v2017_08 "Drer\zgc:123295, Drer\LOC562139, Drer\tmprss4b, Drer\zgc:163079, Drer\zgc:55888, Drer\prss60.3, Drer\ctrl, Drer\si:dkeyp-93a5.2, Drer\prss60.1, Drer\zgc:153968, Drer\prss60.2, Drer\zgc:92590, Drer\zgc:112160, Drer\try, Drer\zgc:112038" - "Cele\rab-11.1, Cele\svh-1, Cele\try-1" - "Mmus\Prss3, Mmus\Gm10334, Mmus\Try10, Mmus\Prss42, Mmus\2210010C04Rik, Mmus\Try4, Mmus\Prss2, Mmus\Prss1, Mmus\Ctrl, Mmus\Gm5771, Mmus\Prss34" "Hsap\PRSS1, Hsap\PRSS42, Hsap\CTRL, Hsap\PRSS3" DRSC01768 K 0.016076789 -0.063012137 -0.420297006 -0.048181006 -0.242862419 1.550058018 FBgn0033000 CG14464 - http://flybase.org/reports/FBgn0033000 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG40285, BcDNA:LD29015, CG14464" "IPR029264:ARF7 effector protein, C-terminal, IPR026515:ARL14 effector protein" CG14464 11-Aug-17 DroID_v2017_08 Drer\arl14ep - Cele\B0336.5 "Xtro\arl14epl, Xtro\arl14ep" "Mmus\Thap7, Mmus\Arl14ep, Mmus\Arl14epl" "Hsap\THAP7, Hsap\THAP8, Hsap\ARL14EP, Hsap\ARL14EPL" FBgn0022365 Pt-7A Adult protein-7A http://flybase.org/reports/FBgn0022365 - gene - - - Pt-7A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039284 CG13652 - http://flybase.org/reports/FBgn0039284 protein_coding_gene - - - CG13652 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "tormogen cell,mesothoracic tergum" FBgn0060654 l(3)S083005b lethal (3) S083005b http://flybase.org/reports/FBgn0060654 gene - - - "0830/05, l(3)S083005b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260059 2L1749 - http://flybase.org/reports/FBgn0260059 gene - - - 2L1749 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0043573 S(faf)244 S(faf)244 http://flybase.org/reports/FBgn0043573 gene - - - S(faf)244 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033283 CG11635 - http://flybase.org/reports/FBgn0033283 protein_coding_gene - - - CG11635 "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG11635 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266048 CR44813 - http://flybase.org/reports/FBgn0266048 non_protein_coding_gene - - - "CR44813, lincRNA.390" - CR44813 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030976 CG7378 - http://flybase.org/reports/FBgn0030976 protein_coding_gene "protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR020405, InterPro:IPR020417, InterPro:IPR020422 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement" "protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR020405, InterPro:IPR020417, InterPro:IPR020422 protein dephosphorylation ; GO:0006470 | non-traceable author statement" cellular_component ; GO:0005575 | no biological data available "BcDNA:RH25447, CG7378, MKP-like" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR020405:Atypical dual specificity phosphatase, subfamily A, IPR020417:Atypical dual specificity phosphatase, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like" CG7378 11-Aug-17 DroID_v2017_08 "Drer\dusp16, Drer\dupd1, Drer\dusp10, Drer\si:ch211-203d1.3, Drer\dusp7, Drer\si:ch211-195b15.8, Drer\dusp3a, Drer\dusp19b, Drer\dusp13a, Drer\si:ch211-223p8.8, Drer\dusp12, Drer\dusp14, Drer\dusp19a, Drer\si:dkey-175m17.7, Drer\dusp22a, Drer\dusp1, Drer\zgc:153981, Drer\dusp2, Drer\dusp27, Drer\styx, Drer\zgc:153044, Drer\dusp6, Drer\dusp8b, Drer\dusp8a, Drer\si:ch1073-184j22.2, Drer\styxl1, Drer\ssh2a, Drer\dusp26, Drer\ssh1a, Drer\dusp5, Drer\dusp22b, Drer\dusp3b, Drer\si:ch211-121a2.2, Drer\ssh1b, Drer\dusp4, Drer\ssh2b" "Scer\MSG5, Scer\SDP1, Scer\YVH1, Scer\PPS1" "Cele\F13D11.3, Cele\lip-1, Cele\Y54F10BM.13, Cele\W09H1.1, Cele\F26A3.4, Cele\C04F12.8, Cele\C16A3.2" "Xtro\dusp19, Xtro\dusp4, Xtro\dusp22, Xtro\dusp22a, Xtro\dusp9, Xtro\epm2a, Xtro\dusp5, Xtro\styx, Xtro\ssh1, Xtro\dupd1, Xtro\ssh2, Xtro\dusp1, Xtro\dusp6, Xtro\dusp12, Xtro\dusp18, Xtro\styxl1, Xtro\dusp26, Xtro\dusp10" "Mmus\Styx, Mmus\Ssh2, Mmus\Dusp4, Mmus\Dusp6, Mmus\Dusp8, Mmus\Dusp19, Mmus\Dusp16, Mmus\Dusp13, Mmus\Dusp3, Mmus\Dusp18, Mmus\Epm2a, Mmus\Dusp7, Mmus\Dupd1, Mmus\Styxl1, Mmus\Dusp2, Mmus\Dusp14, Mmus\Ssh1, Mmus\Ssh3, Mmus\Dusp27, Mmus\Dusp5, Mmus\Dusp15, Mmus\Dusp9, Mmus\Dusp1, Mmus\Dusp10, Mmus\Dusp12, Mmus\Dusp22, Mmus\Dusp26, Mmus\Dusp21" "Hsap\DUSP1, Hsap\DUSP6, Hsap\DUSP27, Hsap\SSH2, Hsap\DUSP9, Hsap\DUSP21, Hsap\EPM2A, Hsap\SSH1, Hsap\DUSP15, Hsap\SSH3, Hsap\DUPD1, Hsap\DUSP12, Hsap\DUSP22, Hsap\DUSP26, Hsap\DUSP4, Hsap\DUSP18, Hsap\STYX, Hsap\DUSP16, Hsap\DUSP19, Hsap\DUSP8, Hsap\DUSP3, Hsap\DUSP13, Hsap\STYXL1, Hsap\DUSP7, Hsap\DUSP2, Hsap\DUSP5, Hsap\DUSP10" viable FBgn0002050 l(2)37Fc lethal (2) 37Fc http://flybase.org/reports/FBgn0002050 - gene - - - "l(2)E42, l(2)37Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0021834 l(2)k15817 lethal (2) k15817 http://flybase.org/reports/FBgn0021834 - gene - - - l(2)k15817 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065526 l(2)SH1118 lethal (2) SH1118 http://flybase.org/reports/FBgn0065526 gene - - - "l(2)SH1118, l(2)SH2 1118" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259585 B2030 - http://flybase.org/reports/FBgn0259585 gene - - - B2030 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible metathoracic leg FBgn0034139 CG4927 - http://flybase.org/reports/FBgn0034139 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP42, CG4927" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG4927 11-Aug-17 DroID_v2017_08 - - Cele\svh-1 - "Mmus\Prss12, Mmus\F12, Mmus\Plat, Mmus\Hgfac, Mmus\Plau, Mmus\Habp2" Hsap\MASP1 "viable,fertile" DRSC06903 I 1.700280649 -0.04912185 -1.071771863 -0.039939986 0.846974055 -0.144782249 FBgn0038943 CG5391 - http://flybase.org/reports/FBgn0038943 protein_coding_gene - - - CG5391 - CG5391 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000002 5SrRNA 5S ribosomal RNA http://flybase.org/reports/FBgn0000002 FBgn0010528 rRNA_gene - - cytosolic large ribosomal subunit ; GO:0022625 | non-traceable author statement "5S RNA, 5S rRNA, 5SrDNA, 5S-rDNA, 5SRNA, 5S rDNA, 5S, 2S rRNA, l(2)03068, PZ03068, RNA X, Dm5S, 5SrRNA, rRNA, 5S_DM" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0261458 capt capulet http://flybase.org/reports/FBgn0261458 protein_coding_gene actin binding ; GO:0003779 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 actin binding ; GO:0003779 | inferred from sequence or structural similarity adenylate cyclase binding ; GO:0008179 | inferred from sequence or structural similarity with PomBase:SPCC306.09c adenylate cyclase binding ; GO:0008179 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype regulation of adenylate cyclase activity ; GO:0045761 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 actin filament organization ; GO:0007015 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype actin polymerization or depolymerization ; GO:0008154 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from genetic interaction with Dys oogenesis ; GO:0048477 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cortical actin cytoskeleton ; GO:0030864 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 "capt, CG5061, CG33979, cyclase-associated protein, capping protein, CAP, Cap, acu, cap, Capt, Acap, l(2)06955, Dcap, CG5074, BcDNA:LD24380, punc, CP" "IPR001837:Adenylate cyclase-associated CAP, IPR003124:WH2 domain, IPR006599:CARP motif, IPR013912:Adenylate cyclase-associated CAP, C-terminal, IPR013992:Adenylate cyclase-associated CAP, N-terminal, IPR017901:C-CAP/cofactor C-like domain, IPR028417:CAP, conserved site, C-terminal" CG33979 11-Aug-17 DroID_v2017_08 "Drer\cap2, Drer\cap1" Scer\SRV2 "Cele\cas-1, Cele\cas-2, Cele\Y65B4A.4" "Xtro\cap2, Xtro\cap1" "Mmus\Cap1, Mmus\Cap2" "Hsap\CAP1, Hsap\CAP2" FBgn0050439 CG30439 - http://flybase.org/reports/FBgn0050439 protein_coding_gene - - - CG30439 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053504 snRNA:U7 small nuclear RNA U7 http://flybase.org/reports/FBgn0053504 snRNA_gene mRNA binding ; GO:0003729 | inferred from direct assay histone mRNA metabolic process ; GO:0008334 | inferred from direct assay mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype nuclear body ; GO:0016604 | inferred from direct assay cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay histone locus body ; GO:0035363 | inferred from direct assay U7 snRNP ; GO:0005683 | inferred from direct assay "U7 snRNA, CR33504, snRNA:U7, U7, U7snRNA, 63E-F U7" - CR33504 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile,viable" FBgn0065252 l(2)SH2114 lethal (2) SH2114 http://flybase.org/reports/FBgn0065252 gene - - - "l(2)SH2114, l(2)SH2 2114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0063915 McClintock\pol McClintock element pol http://flybase.org/reports/FBgn0063915 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - McClintock\pol "IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004111 opa-e opa repeat http://flybase.org/reports/FBgn0004111 - repeat_region - - - "opa, CAX repeat, strep, CAX, M-repeat, M, opa-e" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016678 Mab13G5 Monoclonal antibody 13G5 http://flybase.org/reports/FBgn0016678 - gene - - - Mab13G5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046121 E(To)4 E(To)4 http://flybase.org/reports/FBgn0046121 gene - - - E(To)4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036958 CG17233 - http://flybase.org/reports/FBgn0036958 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6918, CG17233" "IPR025451:Domain of unknown function DUF4211, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain" CG17233 11-Aug-17 DroID_v2017_08 "Drer\ccdc82, Drer\qser1" - Cele\eor-2 - "Mmus\Prr12, Mmus\Qser1, Mmus\Ccdc82" "Hsap\QSER1, Hsap\PRR12, Hsap\CCDC82" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266308 CR44973 - http://flybase.org/reports/FBgn0266308 non_protein_coding_gene - - - CR44973 - CR44973 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085319 CG34290 - http://flybase.org/reports/FBgn0085319 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG34290 "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG34290 11-Aug-17 DroID_v2017_08 "Drer\LOC103908930, Drer\prss59.1, Drer\prss59.2, Drer\try, Drer\si:dkey-33m11.8, Drer\zgc:92590, Drer\LOC560023" - Cele\svh-1 "Xtro\LOC496746, Xtro\prss1, Xtro\prss1.2, Xtro\prss3, Xtro\try10, Xtro\prss2" "Mmus\Try10, Mmus\Prss1, Mmus\Prss2, Mmus\Gm2663, Mmus\1810009J06Rik, Mmus\Prss3, Mmus\Try5, Mmus\2210010C04Rik, Mmus\Gm10334, Mmus\Try4, Mmus\Gm5771" "Hsap\PRSS1, Hsap\PRSS3" FBgn0038603 PKD Protein Kinase D http://flybase.org/reports/FBgn0038603 protein_coding_gene "protein kinase C activity ; GO:0004697 | inferred from electronic annotation with InterPro:IPR015727 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR015727, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR015727 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein kinase D signaling ; GO:0089700 | inferred from biological aspect of ancestor with PANTHER:PTN000540182" cytoplasm ; GO:0005737 | inferred from direct assay "PKD, 150131_at, PKCm, CG7125, dPKD" "IPR000719:Protein kinase domain, IPR001849:Pleckstrin homology domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011993:PH domain-like, IPR015727:Protein kinase C mu-related, IPR017441:Protein kinase, ATP binding site, IPR020454:Diacylglycerol/phorbol-ester binding" CG7125 11-Aug-17 DroID_v2017_08 "Drer\zgc:175248, Drer\LOC797974, Drer\prkd3, Drer\prkd1" Scer\CLA4 "Cele\F48G7.9, Cele\F48G7.10, Cele\R12G8.1, Cele\dkf-1, Cele\dkf-2" "Xtro\prkd1, Xtro\prkd3" "Mmus\Prkd3, Mmus\Prkd2, Mmus\Prkd1" "Hsap\PRKD1, Hsap\PRKD3, Hsap\PRKD2" viable FBgn0005512 l(2)25Bg lethal (2) 25Bg http://flybase.org/reports/FBgn0005512 - gene - - - "jf16, l(2)jf16, l(2)25Bg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024884 l(2)03055 lethal (2) 03055 http://flybase.org/reports/FBgn0024884 - gene - - - "3055, l(2)03055" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015485 l(2)46Ci lethal (2) 46Ci http://flybase.org/reports/FBgn0015485 FBgn0019715 gene - - - "M, 17.5, l(2)46CFm, l(2)46Ci" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0033815 CG4676 - http://flybase.org/reports/FBgn0033815 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG4676 "IPR001594:Palmitoyltransferase, DHHC domain" CG4676 11-Aug-17 DroID_v2017_08 "Drer\zdhhc1, Drer\zgc:77880, Drer\zdhhc21, Drer\zdhhc8b, Drer\zdhhc12b, Drer\zdhhc14, Drer\zdhhc9, Drer\zdhhc23a, Drer\zdhhc18a, Drer\zdhhc24, Drer\zdhhc3b, Drer\zdhhc7, Drer\zdhhc20b, Drer\LOC100334198, Drer\zdhhc5b, Drer\zdhhc12a, Drer\zdhhc22, Drer\zdhhc3a, Drer\zdhhc5a, Drer\zdhhc23b, Drer\zdhhc20a" "Scer\ERF2, Scer\PFA5" "Cele\dhhc-10, Cele\dhhc-12, Cele\dhhc-1, Cele\dhhc-9" "Xtro\zdhhc9, Xtro\zdhhc8, Xtro\zdhhc14, Xtro\zdhhc21, Xtro\zdhhc3, Xtro\zdhhc12, Xtro\dnz1, Xtro\zdhhc24, Xtro\zdhhc7, Xtro\zdhhc1" "Mmus\Zdhhc21, Mmus\Zdhhc11, Mmus\Zdhhc20, Mmus\Zdhhc12, Mmus\Zdhhc23, Mmus\Zdhhc3, Mmus\Zdhhc7, Mmus\Zdhhc22, Mmus\Zdhhc9, Mmus\Zdhhc8, Mmus\Zdhhc25, Mmus\Zdhhc24, Mmus\Zdhhc14, Mmus\Zdhhc19, Mmus\Zdhhc18, Mmus\Zdhhc5, Mmus\Zdhhc1" "Hsap\ZDHHC8, Hsap\ZDHHC19, Hsap\ZDHHC1, Hsap\ZDHHC11, Hsap\ZDHHC23, Hsap\ZDHHC7, Hsap\ZDHHC20, Hsap\ZDHHC14, Hsap\ZDHHC5, Hsap\ZDHHC9, Hsap\ZDHHC12, Hsap\ZDHHC24, Hsap\ZDHHC18, Hsap\ZDHHC3, Hsap\ZDHHC21, Hsap\ZDHHC22" viable FBgn0027546 CG4766 - http://flybase.org/reports/FBgn0027546 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "gh11415, BcDNA:GH11415, CG4766" "IPR024810:Mab-21 domain, IPR020950:Protein male abnormal 21-like 1/2" CG4766 11-Aug-17 DroID_v2017_08 "Drer\mab21l1, Drer\mb21d2, Drer\mab21l3, Drer\itprip, Drer\si:dkey-11f12.2, Drer\mab21l2, Drer\LOC556707, Drer\itpripl2" - Cele\mab-21 "Xtro\mb21d2, Xtro\mab21l1, Xtro\mab21l2" "Mmus\Itpripl1, Mmus\Mab21l3, Mmus\Itprip, Mmus\Mab21l2, Mmus\Itpripl2, Mmus\Tmem102, Mmus\Mb21d2, Mmus\Mb21d1, Mmus\2310007B03Rik, Mmus\Mab21l1" "Hsap\MAB21L3, Hsap\TMEM102, Hsap\ITPRIPL2, Hsap\MAB21L1, Hsap\MAB21L2, Hsap\ITPRIPL1, Hsap\ITPRIP, Hsap\MB21D1, Hsap\MB21D2, Hsap\C2orf54" viable FBgn0014271 l(2)k09619 lethal (2) k09619 http://flybase.org/reports/FBgn0014271 - gene - - - l(2)k09619 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0260057 2L3937 - http://flybase.org/reports/FBgn0260057 gene - - - 2L3937 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0045486 Gr36b Gustatory receptor 36b http://flybase.org/reports/FBgn0045486 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr36B.2, CG15137, Gr36B2, CG31744, Gr36b, GR36b" IPR013604:7TM chemoreceptor CG31744 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - viable FBgn0001187 Hex-C Hexokinase C http://flybase.org/reports/FBgn0001187 FBgn0034003 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001312, InterPro:IPR022672, InterPro:IPR022673 glucose binding ; GO:0005536 | inferred from electronic annotation with InterPro:IPR001312 mannokinase activity ; GO:0019158 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 fructokinase activity ; GO:0008865 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 hexokinase activity ; GO:0004396 | inferred from direct assay glucokinase activity ; GO:0004340 | inferred from biological aspect of ancestor with PANTHER:PTN000455350" carbohydrate phosphorylation ; GO:0046835 | inferred from electronic annotation with InterPro:IPR001312 glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular glucose homeostasis ; GO:0001678 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 "Hex-C, CT22069, HK, DM2, CG8094, HEX, Hk, HEX-C, Hex-c, Hex, HEX-3, Hex-3, Fk, HK-C, HexC" "IPR001312:Hexokinase, IPR022672:Hexokinase, N-terminal, IPR022673:Hexokinase, C-terminal" CG8094 11-Aug-17 DroID_v2017_08 "Drer\hkdc1, Drer\gck, Drer\hk2, Drer\hk1" "Scer\EMI2, Scer\HXK1, Scer\HXK2, Scer\GLK1, Scer\YLR446W" "Cele\hxk-2, Cele\hxk-3, Cele\hxk-1" "Xtro\hk2, Xtro\gck, Xtro\hk1" "Mmus\Gck, Mmus\Hk3, Mmus\Hkdc1, Mmus\Hk2, Mmus\Hk1" "Hsap\HKDC1, Hsap\HK1, Hsap\HK2, Hsap\GCK, Hsap\HK3" "electrophoretic variant,viable,visible" "chaeta,trichogen cell,supernumerary,tormogen cell" FBgn0039625 beta4GalNAcTB beta4GalNAcTB http://flybase.org/reports/FBgn0039625 protein_coding_gene "beta-1,4-N-acetylgalactosaminyltransferase activity ; GO:0033207 | inferred from direct assay N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity ; GO:0033842 | inferred from direct assay acetylgalactosaminyltransferase activity ; GO:0008376 | inferred from direct assay" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR003859 glycolipid biosynthetic process ; GO:0009247 | inferred from direct assay N-acetylglucosamine metabolic process ; GO:0006044 | inferred from direct assay glycosphingolipid biosynthetic process ; GO:0006688 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay "CG14517, dbeta4GalTB, beta4GalTB, beta4GalNAcTB" "IPR003859:Beta-1,4-galactosyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases, IPR027995:Galactosyltransferase, N-terminal, IPR027791:Galactosyltransferase, C-terminal" CG14517 11-Aug-17 DroID_v2017_08 "Drer\b4galt1l, Drer\b4galt5, Drer\b4galt3, Drer\si:dkey-199f5.8, Drer\b4galt2, Drer\b4galt4, Drer\b4galt1, Drer\b4galt6" Scer\TMA20 Cele\bre-4 "Xtro\b4galt1.2, Xtro\LOC100485024, Xtro\b4galt1.1, Xtro\b4galt6, Xtro\b4galt3, Xtro\b4galt5, Xtro\b4galt2, Xtro\b4galt4" "Mmus\B4galt1, Mmus\B4galt4, Mmus\B4galt3, Mmus\B4galt2, Mmus\B4galt5, Mmus\B4galt6" "Hsap\B4GALT4, Hsap\B4GALT2, Hsap\B4GALT5, Hsap\B4GALT3, Hsap\B4GALT6, Hsap\B4GALT1" "viable,fertile" FBgn0070011 BG01296 BG01296 http://flybase.org/reports/FBgn0070011 gene - - - BG01296 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0037688 CG9356 - http://flybase.org/reports/FBgn0037688 protein_coding_gene - Golgi to plasma membrane protein transport ; GO:0043001 | inferred from electronic annotation with InterPro:IPR027095 Golgi organization ; GO:0007030 | inferred from electronic annotation with InterPro:IPR027095 - "CG9356, Golgin-45" IPR027095:Golgin-45 CG9356 11-Aug-17 DroID_v2017_08 Drer\blzf1 - Cele\R12B2.2 Xtro\blzf1 Mmus\Blzf1 Hsap\BLZF1 FBgn0029167 Hml Hemolectin http://flybase.org/reports/FBgn0029167 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 protein homodimerization activity ; GO:0042803 | inferred from direct assay chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 hemostasis ; GO:0007599 | inferred from expression pattern melanization defense response ; GO:0035006 | NOT inferred from mutant phenotype hemolymph coagulation ; GO:0042381 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype hemostasis ; GO:0007599 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay "Hml, hml, CG7002, d-hml, CT21553" "IPR000421:Coagulation factor 5/8 C-terminal domain, IPR000742:EGF-like domain, IPR001007:VWFC domain, IPR001846:von Willebrand factor, type D domain, IPR002557:Chitin binding domain, IPR002919:Trypsin Inhibitor-like, cysteine rich domain, IPR006207:Cystine knot, C-terminal, IPR012111:Hemolectin/hemocytin, IPR013032:EGF-like, conserved site, IPR014853:Uncharacterised domain, cysteine-rich, IPR008979:Galactose-binding domain-like, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG7002 11-Aug-17 DroID_v2017_08 "Drer\LOC100147849, Drer\asic2, Drer\otogl, Drer\muc2.1, Drer\si:ch211-39f2.3, Drer\tecta, Drer\LOC100329651, Drer\fras1, Drer\muc5f, Drer\scospondin, Drer\LOC101887000, Drer\vwf, Drer\si:dkey-65b12.6, Drer\si:dkey-239b22.1, Drer\LOC799643, Drer\muc5.2, Drer\LOC100147904, Drer\muc5.1, Drer\otog, Drer\ch1073-291c23.1, Drer\si:dkey-266m15.6, Drer\wu:fb63a08" "Scer\HPF1, Scer\HKR1, Scer\FLO9, Scer\YIL169C, Scer\MSB2, Scer\FLO1, Scer\FIG2, Scer\PRM7, Scer\YMR317W, Scer\FLO5, Scer\FLO11" "Cele\dpy-6, Cele\C18H7.1, Cele\H43E16.1, Cele\ZC178.2, Cele\clec-223, Cele\F36H9.4, Cele\C53B7.2, Cele\T01D3.6, Cele\C25E10.10, Cele\C10G8.4, Cele\H02F09.3, Cele\F53C11.9, Cele\srap-1" "Xtro\muc6, Xtro\tecta.1, Xtro\zan, Xtro\LOC100485197, Xtro\LOC100497909, Xtro\vwf, Xtro\otogl, Xtro\fras1, Xtro\kcp, Xtro\LOC100492852" "Mmus\Kcp, Mmus\Fcgbp, Mmus\Muc5ac, Mmus\Vwce, Mmus\Otogl, Mmus\Otog, Mmus\Fras1, Mmus\Muc5b, Mmus\Tecta, Mmus\Muc2, Mmus\Muc6, Mmus\9530053A07Rik, Mmus\Muc4, Mmus\Zan, Mmus\Sspo, Mmus\Vwf, Mmus\Muc19" "Hsap\FRAS1, Hsap\MUC16, Hsap\MUC6, Hsap\OTOG, Hsap\FCGBP, Hsap\MUC4, Hsap\MUC2, Hsap\MUC19, Hsap\MUC5B, Hsap\MUC5AC, Hsap\VWF, Hsap\TECTA, Hsap\VWCE, Hsap\ZAN, Hsap\OTOGL, Hsap\SSPO, Hsap\MUC17" " embryonic stage | stage 17 , larval stage | first instar , larval stage " " embryonic hemocyte

, larval hemocyte

, organism

, crystal cell | subset

, plasmatocyte | subset

" "viable,fertile,immune response defective" FBgn0028385 cod capodimonte http://flybase.org/reports/FBgn0028385 gene - - - cod - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004068 fs(2)mel2 female sterile (2) maternal effect lethal 2 http://flybase.org/reports/FBgn0004068 - gene - - - "mel 2, fs(2)mel2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "cephalopharyngeal skeleton,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,embryo,maternal effect" FBgn0267132 CR45572 - http://flybase.org/reports/FBgn0267132 non_protein_coding_gene - - - CR45572 - CR45572 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040050 CG17403 - http://flybase.org/reports/FBgn0040050 protein_coding_gene - - - CG17403 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065757 l(2)SH0486 lethal (2) SH0486 http://flybase.org/reports/FBgn0065757 gene - - - "l(2)SH0486, l(2)SH2 0486" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0275436 PheRS-m "Phenylalanyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0275436 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002319, InterPro:IPR004530, InterPro:IPR005121 phenylalanine-tRNA ligase activity ; GO:0004826 | inferred from biological aspect of ancestor with PANTHER:PTN000165932 phenylalanine-tRNA ligase activity ; GO:0004826 | traceable author statement tRNA binding ; GO:0000049 | inferred from sequence or structural similarity with UniProtKB:O95363 phenylalanine-tRNA ligase activity ; GO:0004826 | inferred from sequence or structural similarity with UniProtKB:O95363 phenylalanine-tRNA ligase activity ; GO:0004826 | inferred from sequence or structural similarity with UniProtKB:P08425" phenylalanyl-tRNA aminoacylation ; GO:0006432 | traceable author statement tRNA processing ; GO:0008033 | inferred from sequence or structural similarity with UniProtKB:O95363 phenylalanyl-tRNA aminoacylation ; GO:0006432 | inferred from biological aspect of ancestor with PANTHER:PTN000165932 phenylalanyl-tRNA aminoacylation ; GO:0006432 | inferred from sequence or structural similarity with UniProtKB:O95363 phenylalanyl-tRNA aminoacylation ; GO:0006432 | inferred from sequence or structural similarity with UniProtKB:P08425 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000165999 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P08425 mitochondrion ; GO:0005739 | traceable author statement "mtPheRS, PheRS, FRS, Pts, CG13348, Aats-phe, PheRS-m, Aats-phe-m" "IPR002319:Phenylalanyl-tRNA synthetase, IPR004530:Phenylalanyl-tRNA synthetase, class IIc, mitochondrial, IPR005121:Ferrodoxin-fold anticodon-binding domain, IPR006195:Aminoacyl-tRNA synthetase, class II" CG13348 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-71l1.3, Drer\fars2" Scer\MSF1 Cele\fars-2 "Xtro\alg9, Xtro\fars2" "Mmus\Fdxacb1, Mmus\Fars2" "Hsap\FARS2, Hsap\FDXACB1" "viable,visible,decreased cell size,cell autonomous,somatic clone" "trichogen cell,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0032285 CG17108 - http://flybase.org/reports/FBgn0032285 protein_coding_gene - - - "CT33647, gh23489, BEST:GH23489, CG17108" - CG17108 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0029769 frma fra mauro http://flybase.org/reports/FBgn0029769 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497 negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype" - "BEST:GH09377, CG3239, frma" "IPR000718:Peptidase M13, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR008753:Peptidase M13, N-terminal domain" CG3239 11-Aug-17 DroID_v2017_08 "Drer\mmel1, Drer\phex, Drer\ece2b, Drer\ece1" - "Cele\nep-18, Cele\nep-16, Cele\nep-21, Cele\nep-7, Cele\nep-8, Cele\nep-24, Cele\nep-19, Cele\nep-13, Cele\nep-6, Cele\nep-20, Cele\nep-10, Cele\nep-12, Cele\nep-5, Cele\nep-26, Cele\nep-9, Cele\nep-23, Cele\nep-3, Cele\nep-17" "Xtro\ece2, Xtro\mmel1, Xtro\ecel1, Xtro\ece1" "Mmus\Ece1, Mmus\Ece2, Mmus\Mme, Mmus\Ecel1, Mmus\Kel, Mmus\Mmel1, Mmus\Phex" "Hsap\MME, Hsap\MMEL1, Hsap\ECE2, Hsap\PHEX, Hsap\KEL, Hsap\ECEL1, Hsap\ECE1" "mating behavior defective,female limited,female semi-fertile" FBgn0039726 eIF2Balpha eukaryotic translation initiation factor 2B subunit alpha http://flybase.org/reports/FBgn0039726 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000001734 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity enzyme regulator activity ; GO:0030234 | inferred from genetic interaction with SGD:S000001734 translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD:S000001734 lateral inhibition ; GO:0046331 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000027918 eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity with SGD:S000001734 cytosol ; GO:0005829 | inferred from sequence or structural similarity "CG7883, DeIF2Balpha, eIF2B-alpha, Eif2b, eIF2Balpha" IPR000649:Initiation factor 2B-related CG7883 11-Aug-17 DroID_v2017_08 Drer\eif2b1 Scer\GCN3 "Cele\F11A3.2, Cele\ZK1098.4" Xtro\eif2b1 Mmus\Eif2b1 Hsap\EIF2B1 "viable,visible" "chaeta,trichogen cell" FBgn0050287 CG30287 - http://flybase.org/reports/FBgn0050287 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP37, SPH37, CG10450, CG30287" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG30287 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-93a5.3, Drer\zgc:165423, Drer\gzmk, Drer\zgc:163079, Drer\si:ch211-165b19.9, Drer\ovch1, Drer\masp2, Drer\si:ch211-165b19.8, Drer\zgc:92313, Drer\gzma, Drer\gzm3, Drer\si:dkey-16l2.17, Drer\si:ch211-165b19.5, Drer\f9a, Drer\LOC558805, Drer\LOC100004427, Drer\cfd" - "Cele\try-1, Cele\try-3, Cele\svh-1, Cele\try-6" - "Mmus\Klk15, Mmus\Tmprss12, Mmus\Klk1b9, Mmus\Klk9, Mmus\Egfbp2, Mmus\Klk1b5" "Hsap\TMPRSS12, Hsap\KLK9, Hsap\MASP1, Hsap\KLK15" FBgn0029863 CG3823 - http://flybase.org/reports/FBgn0029863 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 CG3823 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG3823 11-Aug-17 DroID_v2017_08 "Drer\clvs2, Drer\sec14l8, Drer\ttpa, Drer\rlbp1b, Drer\sec14l7, Drer\rlbp1a, Drer\ttpal" "Scer\YKL091C, Scer\SFH5, Scer\SEC14" - "Xtro\sec14l1, Xtro\clvs2, Xtro\mospd2, Xtro\sec14l3, Xtro\sec14l5, Xtro\clvs1, Xtro\ttpal, Xtro\ttpa, Xtro\rlbp1" "Mmus\Sec14l3, Mmus\Sec14l5, Mmus\Sec14l1, Mmus\Sec14l2, Mmus\Clvs2, Mmus\Sec14l4, Mmus\Ttpa, Mmus\Rlbp1, Mmus\Clvs1, Mmus\Ttpal" "Hsap\CLVS2, Hsap\SEC14L6, Hsap\SEC14L2, Hsap\SEC14L4, Hsap\CLVS1, Hsap\TTPAL, Hsap\SEC14L5, Hsap\SEC14L1, Hsap\RLBP1, Hsap\SEC14L3, Hsap\TTPA" "viable,fertile" FBgn0022745 anon-J1b anon-J1b http://flybase.org/reports/FBgn0022745 - gene - - - "J1, anon-J1b" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040004 CG12552 - http://flybase.org/reports/FBgn0040004 protein_coding_gene - - - CG12552 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263995 cpo couch potato http://flybase.org/reports/FBgn0263995 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity dormancy process ; GO:0022611 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "cpo, CPO, CG43738, CG31243, ORE-17, CG12349, CG18435, cg18435, Cpo, l(3)6015, 6015, 5339, 3603, 1824, l(3)s2336, l(3)rJ553, l(3)j9B3, l(3)j7E2, l(3)j4D4, l(3)j4A1, l(3)01432, E(sda)N, CG18434, BcDNA:AT31405, Line N, CG42457" IPR000504:RNA recognition motif domain CG43738 11-Aug-17 DroID_v2017_08 "Drer\rbpms2a, Drer\LOC100537153, Drer\rbpms2b" "Scer\WHI3, Scer\WHI4, Scer\YGR250C" "Cele\mec-8, Cele\rsp-2" Xtro\rbpms "Mmus\Rbpms2, Mmus\Rbpms" "Hsap\RBPMS2, Hsap\RBPMS" embryonic stage " neuron &&of chordotonal organ

, embryonic peripheral nervous system

" embryonic stage " central nervous system

{ 0 AS-C- } , peripheral nervous system

, glial cell

, neuron chordotonal organ

{ 0 AS-C- } , sensory organ mother cell

{ - da* } , posterior spiracle

{ - AS-C- } , central nervous system

{ $ da* } , peripheral nervous system

{ 0 AS-C- } , peripheral nervous system

{ 0 da* } , embryonic central nervous system

, neuron

, embryonic/larval midgut

, midgut

{ 0 da* } , glial cell

{ 0 AS-C- } , midgut

" DRSC13265 I 1.374389261 1.553335766 -0.049318037 -0.250038696 -0.012647936 -0.182963195 FBgn0041236 Gr59d Gustatory receptor 59d http://flybase.org/reports/FBgn0041236 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "CG30330, Gr59D1, 59D1, 59D.1, GR59D.1, CG13543, Gr59d, GR59d" IPR013604:7TM chemoreceptor CG30330 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0032800 CG10137 - http://flybase.org/reports/FBgn0032800 protein_coding_gene - - - CG10137 IPR008979:Galactose-binding domain-like CG10137 11-Aug-17 DroID_v2017_08 "Drer\ace, Drer\ace2, Drer\cep104" - "Cele\T06D8.2, Cele\C40H1.3, Cele\F28C6.9, Cele\C06A8.8" "Xtro\ace2, Xtro\cep104, Xtro\ace" "Mmus\Ace, Mmus\Ace3, Mmus\Cep104, Mmus\Ace2" "Hsap\ACE2, Hsap\ACE, Hsap\CEP104" viable FBgn0051866 Ada1-2 transcriptional Adaptor 1-2 http://flybase.org/reports/FBgn0051866 protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001083423 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity with SGD:S000006175 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001083423 histone acetylation ; GO:0016573 | inferred from sequence or structural similarity with SGD:S000006175 histone H3 acetylation ; GO:0043966 | inferred from direct assay transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with SGD:S000006175 SAGA complex ; GO:0000124 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Ada1-2, CG31866, Ada1, ada1-2" IPR024738:Transcriptional coactivator Hfi1/Transcriptional adapter 1 CG31866 11-Aug-17 DroID_v2017_08 Drer\tada1 Scer\HFI1 - Xtro\tada1 Mmus\Tada1 Hsap\TADA1 FBgn0013696 mt:tRNA:Ile-GAT mitochondrial transfer RNA:Isoleucine-GAT http://flybase.org/reports/FBgn0013696 FBgn0002867 tRNA_gene - - - "CR34060, tRNA[Ile], mtdbD00006292, mt:tRNA:Ile-GAT, mt:tRNA:I, mt:tRNA[Ile]" - CR34060 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039893 CG13301 - http://flybase.org/reports/FBgn0039893 protein_coding_gene - - - CG13301 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262882 CG43237 - http://flybase.org/reports/FBgn0262882 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43237, lincRNA.333" - CG43237 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020806 ms(2)C32 ms(2)C32 http://flybase.org/reports/FBgn0020806 - gene - - - "2-C32, ms(2)C32" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,chemical sensitive" FBgn0266637 CR45144 - http://flybase.org/reports/FBgn0266637 non_protein_coding_gene - - - CR45144 - CR45144 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010948 l(3)10621 lethal (3) 10621 http://flybase.org/reports/FBgn0010948 - gene - - - l(3)10621 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0005502 slf schlaff http://flybase.org/reports/FBgn0005502 "FBgn0001912, FBgn0003422" gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)25Aa, slf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,cephalopharyngeal skeleton,embryo,posterior,anterior" FBgn0043899 gsb::Mmus\Pax3 Pax3 http://flybase.org/reports/FBgn0043899 engineered_fusion_gene - - - gsb::Mmus\Pax3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067072 Mns Microtubule nucleation suppressor http://flybase.org/reports/FBgn0067072 gene - - - "MINUS, Minus, Mns" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028693 Rpn12 Regulatory particle non-ATPase 12 http://flybase.org/reports/FBgn0028693 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity with SGD:S000001948 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0000502 proteasome assembly ; GO:0043248 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype "proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9566 inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 proteasome complex ; GO:0000502 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000001948" "dRpn12, p30, CG4157, Rpn12, S14" "IPR006746:26S proteasome non-ATPase regulatory subunit Rpn12, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR033464:CSN8/PSMD8/EIF3K" CG4157 11-Aug-17 DroID_v2017_08 Drer\psmd8 Scer\RPN12 Cele\rpn-12 Xtro\psmd8 Mmus\Psmd8 Hsap\PSMD8 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC11275 IEK -2.898831702 -3.190066818 -2.817372184 -1.933076306 1.385172297 -2.642958187 FBgn0011045 l(1)Stark-d lethal (1) of Stark d http://flybase.org/reports/FBgn0011045 FBgn0010212 gene - - - "l(1)Stark-d, l(1)Sd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029955 CG15478 - http://flybase.org/reports/FBgn0029955 protein_coding_gene - - - CG15478 IPR015943:WD40/YVTN repeat-like-containing domain CG15478 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "heart primordium,chaeta,supernumerary" FBgn0051648 CG31648 - http://flybase.org/reports/FBgn0051648 protein_coding_gene copper ion binding ; GO:0005507 | inferred from sequence or structural similarity with SGD:S000006053 aerobic respiration ; GO:0009060 | inferred from sequence or structural similarity with SGD:S000006053 respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with UniProtKB:Q9Y6N1 - "CG6922, CG31648, COXZ" "IPR007533:Cytochrome c oxidase assembly protein CtaG/Cox11, IPR023471:Cytochrome c oxidase assembly protein CtaG/Cox11, domain" CG31648 11-Aug-17 DroID_v2017_08 Drer\cox11 Scer\COX11 Cele\cox-11 Xtro\cox11 Mmus\Cox11 Hsap\COX11 "viable,visible" trichogen cell FBgn0067040 W10 W10 http://flybase.org/reports/FBgn0067040 gene - - - W10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable" FBgn0023096 btv beethoven http://flybase.org/reports/FBgn0023096 FBgn0032657 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" "male courtship behavior ; GO:0008049 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype intraciliary retrograde transport ; GO:0035721 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype auditory behavior ; GO:0031223 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity" cytoplasmic dynein complex ; GO:0005868 | inferred from sequence or structural similarity axoneme ; GO:0005930 | inferred from mutant phenotype cytoplasmic dynein complex ; GO:0005868 | inferred from sequence or structural similarity with UniProtKB:P36022 "CG15148, DHC, Dhc36D, DHC36D, btv, DHC2" "IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026815:Cytoplasmic dynein 2 heavy chain 1, IPR026983:Dynein heavy chain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG15148 11-Aug-17 DroID_v2017_08 "Drer\dnah12, Drer\dnah7, Drer\dnah9l, Drer\si:dkeyp-86b9.1, Drer\wu:fj30b09, Drer\dnah3, Drer\dnah2, Drer\si:dkeyp-87a6.1, Drer\dnah1, Drer\dync1h1, Drer\dnah7l" Scer\DYN1 "Cele\che-3, Cele\dhc-1" "Xtro\dnah14, Xtro\dnah2, Xtro\dnah7" "Mmus\Dnah12, Mmus\Dnah8, Mmus\Dync1h1, Mmus\Dnah1, Mmus\Dnah5, Mmus\Dnah9, Mmus\Dnah6, Mmus\Dnah7a, Mmus\Dnah10, Mmus\Dnah3, Mmus\Dync2h1, Mmus\Dnah17, Mmus\Dnah7b, Mmus\Dnah7c, Mmus\Dnah2, Mmus\Dnah11, Mmus\Dnhd1" "Hsap\DNAH6, Hsap\DNAH8, Hsap\CCDC88B, Hsap\DNAH2, Hsap\DYNC1H1, Hsap\DNAH5, Hsap\DNAH9, Hsap\DNAH14, Hsap\DNHD1, Hsap\DNAH7, Hsap\DNAH12, Hsap\DNAH10, Hsap\DNAH1, Hsap\DNAH3, Hsap\DNAH17, Hsap\DNAH11, Hsap\DYNC2H1" "thermotaxis behavior defective,touch sensitivity defective,locomotor behavior defective,auditory perception defective,neuroanatomy defective,viable,smell perception defective,courtship behavior defective,male,male fertile,song defective,recessive,behavior defective" "abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidium,arista,mechanosensory sensory organ,wing,adult antennal nerve" FBgn0265860 CR44649 - http://flybase.org/reports/FBgn0265860 non_protein_coding_gene - - - CR44649 - CR44649 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031184 CG14615 - http://flybase.org/reports/FBgn0031184 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR013653" - - CG14615 "IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG14615 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-76k16.5, Drer\si:ch73-106k19.2, Drer\si:dkey-76k16.6" - Cele\ZK185.3 - - Hsap\GLYATL3 viable FBgn0001018 fs(3)A9 female sterile (3) A9 http://flybase.org/reports/FBgn0001018 - gene - - - fs(3)A9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0016981 snRNA:K2b small nuclear RNA K2b http://flybase.org/reports/FBgn0016981 - snRNA_gene - - - "K2b, snRNA:K2b" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005093 fs(2)OWc5 female sterile (2) OWc5 http://flybase.org/reports/FBgn0005093 - gene - - - fs(2)OWc5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032233 dpr19 defective proboscis extension response 19 http://flybase.org/reports/FBgn0032233 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG13140, Dpr-19, BcDNA:LP09705, dpr19, Dpr19" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold" CG13140 11-Aug-17 DroID_v2017_08 "Drer\ush2a, Drer\ncam1b, Drer\LOC100333196, Drer\kirrel3a, Drer\igsf9a, Drer\sdk1a, Drer\sdk1b, Drer\si:ch211-264f5.6, Drer\lrit3b, Drer\kirrela, Drer\igsf9bb, Drer\LOC101885444, Drer\kirrel3b, Drer\dscama, Drer\si:dkey-65b12.12, Drer\paplna, Drer\itgb4, Drer\kirrel3l, Drer\lrit3a, Drer\lrit1b, Drer\kirrelb, Drer\si:ch1073-459j12.1, Drer\lrit1a" - Cele\zig-8 "Xtro\nfasc, Xtro\kirrel2, Xtro\igsf9b, Xtro\obsl1, Xtro\lrit3, Xtro\papln" "Mmus\Amica1, Mmus\Lrit1, Mmus\Lrit3, Mmus\Kirrel3, Mmus\Kirrel, Mmus\Ptprq, Mmus\Sdk1, Mmus\Kirrel2, Mmus\Papln, Mmus\Igsf9b" "Hsap\USH2A, Hsap\KIRREL3, Hsap\SDK1, Hsap\CADM3, Hsap\LRIT3, Hsap\KIRREL2, Hsap\CADM4, Hsap\KIRREL, Hsap\LRIT1, Hsap\CADM1, Hsap\PAPLN, Hsap\IGSF9B, Hsap\CADM2" viable FBgn0050154 CG30154 - http://flybase.org/reports/FBgn0050154 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30154 - CG30154 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039405 PIG-P Phosphatidylinositol glycan anchor biosynthesis class P http://flybase.org/reports/FBgn0039405 protein_coding_gene phosphatidylinositol N-acetylglucosaminyltransferase activity ; GO:0017176 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000497247 UDP-glycosyltransferase activity ; GO:0008194 | contributes_to inferred from sequence or structural similarity with SGD:S000002845 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with SGD:S000002845 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000002845 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506 | inferred from biological aspect of ancestor with PANTHER:PTN001094394 "BcDNA:GM30016, Dromel_CG14550_FBtr0084974_mORF, PIG-P, CG14550" IPR013717:PIG-P CG14550 11-Aug-17 DroID_v2017_08 "Drer\pigp, Drer\noa1" Scer\GPI19 Cele\Y48E1B.2 Xtro\pigp "Mmus\Noa1, Mmus\Gm6880, Mmus\Lage3, Mmus\Pigp, Mmus\Gm6890, Mmus\Ctag2" "Hsap\CTAG2, Hsap\LAGE3, Hsap\NOA1, Hsap\PIGP" viable FBgn0085697 CG41568 - http://flybase.org/reports/FBgn0085697 protein_coding_gene - - - CG41568 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262331 mir-999 mir-999 stem loop http://flybase.org/reports/FBgn0262331 miRNA_gene - - - "dme-mir-999, miR-999, mir-999, CR43038, miR999, dme-miR-999" - CR43038 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,lethal - all die before end of P-stage,some die during pharate adult stage" wing FBgn0004040 yea6 yeast 6 http://flybase.org/reports/FBgn0004040 - gene - - - yea6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065420 l(2)SH1525 lethal (2) SH1525 http://flybase.org/reports/FBgn0065420 gene - - - "l(2)SH1525, l(2)SH2 1525" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051343 CG31343 - http://flybase.org/reports/FBgn0051343 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "CG5839, BEST:GH20248, anon-WO0140519.86, CG31343" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG31343 11-Aug-17 DroID_v2017_08 "Drer\lnpep, Drer\anpepb, Drer\erap1b, Drer\si:ch211-106j24.1, Drer\si:ch211-149p5.1, Drer\enpep, Drer\erap1a, Drer\npepps, Drer\anpepa, Drer\si:ch211-276a23.5, Drer\si:ch211-198g19.1, Drer\erap2" "Scer\AAP1, Scer\TMA108, Scer\APE2" "Cele\T12E12.6, Cele\F49B2.6, Cele\VB0395L.1, Cele\mnp-1, Cele\AC3.5, Cele\Y53F4B.20, Cele\T16G12.1, Cele\Y67D8C.9, Cele\Y42A5A.1, Cele\R03G8.6, Cele\pam-1, Cele\R03G8.4, Cele\T07F10.1" "Xtro\lnpep, Xtro\anpep, Xtro\erap1, Xtro\lvrn, Xtro\npepps, Xtro\enpep" "Mmus\Lnpep, Mmus\Npepps, Mmus\Enpep, Mmus\Lvrn, Mmus\Trhde, Mmus\Erap1, Mmus\Anpep" "Hsap\NPEPPS, Hsap\LVRN, Hsap\LNPEP, Hsap\ANPEP, Hsap\TRHDE, Hsap\ENPEP, Hsap\ERAP1, Hsap\ERAP2" viable FBgn0032732 CG15168 - http://flybase.org/reports/FBgn0032732 protein_coding_gene inorganic cation transmembrane transporter activity ; GO:0022890 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 cation transmembrane transport ; GO:0098655 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 early endosome ; GO:0005769 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 "BcDNA:RE09053, CG15168" IPR018937:Magnesium transporter CG15168 11-Aug-17 DroID_v2017_08 Drer\mmgt1 - Cele\emc-5 Xtro\mmgt1 "Mmus\Mmgt1, Mmus\Mmgt2" Hsap\MMGT1 "partially lethal - majority die,some die during pupal stage" FBgn0050043 CG30043 - http://flybase.org/reports/FBgn0050043 protein_coding_gene - - - "CG13161, CG30043" IPR007484:Peptidase M28 CG30043 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\PFF1, Scer\APE3, Scer\YDR415C, Scer\VPS70" "Cele\C44B7.11, Cele\B0495.7" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0260313 GSd445 - http://flybase.org/reports/FBgn0260313 gene - - - GSd445 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031204 CG9562 - http://flybase.org/reports/FBgn0031204 protein_coding_gene - - - "tartan/capricious-like, CT16794, CG9562" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053727 snmRNA:430:CR33727 snmRNA:430:CR33727 http://flybase.org/reports/FBgn0053727 non_protein_coding_gene - - - "CR33727, snmRNA:430:CR33727" - CR33727 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039299 CG11854 - http://flybase.org/reports/FBgn0039299 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG11854 IPR010562:Haemolymph juvenile hormone binding CG11854 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065736 l(2)SH0541 lethal (2) SH0541 http://flybase.org/reports/FBgn0065736 gene - - - "l(2)SH0541, l(2)SH2 0541" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004994 Cor Corroded eye http://flybase.org/reports/FBgn0004994 - gene - - - Cor - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" eye FBgn0053669 CG33669 - http://flybase.org/reports/FBgn0053669 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs03a05.y1, NEST:bs03a05, CG33669" - CG33669 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029115 TO42 TO42 http://flybase.org/reports/FBgn0029115 gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR001075 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001075 "iron-sulfur cluster assembly ; GO:0016226 | inferred from electronic annotation with InterPro:IPR001075, InterPro:IPR017065" - "clot#9754, TO42" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR014824:Scaffold protein Nfu/NifU, N-terminal, IPR001075:NIF system FeS cluster assembly, NifU, C-terminal, IPR017065:NFU1 iron-sulfur cluster scaffold homologue" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037402 Vha14-2 Vacuolar H[+] ATPase 14kD subunit 2 http://flybase.org/reports/FBgn0037402 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR005772 ATPase coupled ion transmembrane transporter activity ; GO:0042625 | inferred from biological aspect of ancestor with PANTHER:PTN001015339" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR005772 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033176 "proton-transporting V-type ATPase, V1 domain ; GO:0033180 | inferred from electronic annotation with InterPro:IPR005772 proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity with Vha14-1 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001015339" "vha14-2, CG1076, Vha14-2" "IPR005772:ATPase, V1 complex, subunit F, eukaryotic, IPR008218:ATPase, V1 complex, subunit F" CG1076 11-Aug-17 DroID_v2017_08 Drer\atp6v1f Scer\VMA7 Cele\vha-9 Xtro\atp6v1f Mmus\Atp6v1f Hsap\ATP6V1F viable FBgn0011215 cash cashews http://flybase.org/reports/FBgn0011215 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "cas, cash" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0044083 E(rst)H186 E(rst)H186 http://flybase.org/reports/FBgn0044083 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H186, E(rst)H186" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0040737 Tango8 Transport and Golgi organization 8 http://flybase.org/reports/FBgn0040737 protein_coding_gene molecular_function ; GO:0003674 | no biological data available Golgi organization ; GO:0007030 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG14503, TANGO8, Tango8" - CG14503 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267612 CR45950 - http://flybase.org/reports/FBgn0267612 non_protein_coding_gene - - - CR45950 - CR45950 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039031 Gbp3 Growth-blocking peptide 3 http://flybase.org/reports/FBgn0039031 protein_coding_gene cytokine activity ; GO:0005125 | inferred from sequence or structural similarity with Gbp1 signal transduction ; GO:0007165 | inferred from sequence or structural similarity with Gbp1 cellular_component ; GO:0005575 | no biological data available "BcDNA:RH17470, CG17244, Gbp3, GBP3" - CG17244 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC15206 K 0.463009169 -0.325969033 1.052178418 -0.225560437 -1.608280657 -0.859813274 FBgn0263476 snoRNA:CG32479-b - http://flybase.org/reports/FBgn0263476 snoRNA_gene - - - snoRNA:CG32479-b - CR43591 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033461 CG12923 - http://flybase.org/reports/FBgn0033461 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12923 IPR031732:Protein of unknown function DUF4729 CG12923 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016842 l(1)N15 lethal (1) N15 http://flybase.org/reports/FBgn0016842 - gene - - - "l(1)N15, N15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038879 CG17298 - http://flybase.org/reports/FBgn0038879 protein_coding_gene - - - "CT35916, BcDNA:RH37844, CG17298" - CG17298 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038816 Lrrk Leucine-rich repeat kinase http://flybase.org/reports/FBgn0038816 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR013684 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN001147562 protein kinase activity ; GO:0004672 | inferred from direct assay Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab5 inferred from physical interaction with Rab7 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W596 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab18" "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR013684 axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from mutant phenotype negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype intracellular distribution of mitochondria ; GO:0048312 | inferred from mutant phenotype regulation of synapse maturation ; GO:0090128 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 autophagy ; GO:0006914 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from direct assay negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype retrograde transport, endosome to Golgi ; GO:0042147 | inferred from genetic interaction with Rab9 regulation of synaptic vesicle endocytosis ; GO:1900242 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 lysosome localization ; GO:0032418 | inferred from mutant phenotype inferred from genetic interaction with Rab7 establishment of Golgi localization ; GO:0051683 | inferred from mutant phenotype" neuromuscular junction ; GO:0031594 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from direct assay dendritic shaft ; GO:0043198 | inferred from direct assay Golgi stack ; GO:0005795 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001147562 cytoplasm ; GO:0005737 | inferred from direct assay dendritic branch point ; GO:1990033 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from direct assay cell body ; GO:0044297 | inferred from direct assay "CT17358, dLRRK, CG5483, Lrrk, LRRK, lrrk, LRRK2, dLrrk" "IPR000719:Protein kinase domain, IPR001611:Leucine-rich repeat, IPR002110:Ankyrin repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013684:Mitochondrial Rho-like, IPR017441:Protein kinase, ATP binding site, IPR032675:Leucine-rich repeat domain, L domain-like, IPR020683:Ankyrin repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR020859:Roc domain, IPR032171:C-terminal of Roc (COR) domain" CG5483 11-Aug-17 DroID_v2017_08 "Drer\lrrk2, Drer\ripk3, Drer\ripk4, Drer\zak, Drer\LOC405768, Drer\dstyk, Drer\si:ch211-120p12.3, Drer\pbk, Drer\ripk2, Drer\map3k9, Drer\map3k10, Drer\ascl1b, Drer\ripk1l, Drer\mos, Drer\lrrk1" - Cele\lrk-1 "Xtro\ankk1, Xtro\zak, Xtro\lrrk1, Xtro\map3k7, Xtro\map3k10, Xtro\pbk, Xtro\dstyk, Xtro\map3k9, Xtro\ripk1, Xtro\lrrk2, Xtro\LOC100490493, Xtro\ripk4, Xtro\mlkl" "Mmus\Zak, Mmus\Ripk4, Mmus\Lrrk1, Mmus\Lrrk2, Mmus\Mos, Mmus\BC021891, Mmus\Pbk, Mmus\Ripk1, Mmus\Mlkl, Mmus\Map3k11, Mmus\Dstyk, Mmus\Ripk2, Mmus\Ripk3, Mmus\Map3k7, Mmus\Map3k9, Mmus\Map3k10" "Hsap\PBK, Hsap\MAP3K7, Hsap\MAP3K10, Hsap\MAP3K9, Hsap\MAP3K21, Hsap\MOS, Hsap\RIPK1, Hsap\RIPK4, Hsap\MAP3K11, Hsap\MAP3K20, Hsap\MLKL, Hsap\LRRK1, Hsap\DSTYK, Hsap\LRRK2, Hsap\RIPK2, Hsap\RIPK3" "viable,neuroanatomy defective,chemical sensitive,locomotor behavior defective,female fertile,reduced,chemical resistant,female sterile,neurophysiology defective,female semi-sterile" "lysosomeCY2,type I bouton,neuromuscular junction,neuromuscular junctionMhc.PW,dopaminergic neuron,adult abdomen,female,dendritic arborizing neuron | third instar larval stage,NMJ bouton,mitochondrion" FBgn0262774 Su(E1)-H - http://flybase.org/reports/FBgn0262774 gene - - - Su(E1)-H - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002900 mus302 mutagen-sensitive 302 http://flybase.org/reports/FBgn0002900 - gene - - - "mus(3)302, mus302" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive,recessive,semidominant,radiation sensitive,female fertile,poor,DNA repair defective" FBgn0011047 l(3)AFA17 lethal (3) AFA17 http://flybase.org/reports/FBgn0011047 FBgn0005200 gene - - - l(3)AFA17 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024492 BITP-15 BITP-15 http://flybase.org/reports/FBgn0024492 - gene - - - BITP-15 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036333 MICAL-like MICAL-like http://flybase.org/reports/FBgn0036333 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 actin binding ; GO:0003779 | inferred from sequence or structural similarity - - "AAK93415, CG11259, MICAL-like" "IPR001715:Calponin homology domain, IPR001781:Zinc finger, LIM-type, IPR022735:Domain of unknown function DUF3585" CG11259 11-Aug-17 DroID_v2017_08 "Drer\micall2b, Drer\micall2a, Drer\mical3b, Drer\mical1, Drer\si:ch211-254c8.2, Drer\mical3a, Drer\micall1a" - - "Xtro\micall1, Xtro\micall2" "Mmus\Micall2, Mmus\2900011O08Rik, Mmus\Micall1" "Hsap\MICAL1, Hsap\MICALL2, Hsap\EHBP1, Hsap\MICALL1" "viable,fertile" FBgn0283510 Pal1 Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 1 http://flybase.org/reports/FBgn0283510 protein_coding_gene peptidylamidoglycolate lyase activity ; GO:0004598 | inferred from direct assay peptide metabolic process ; GO:0006518 | inferred from electronic annotation with InterPro:IPR000720 regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000720 neuronal cell body ; GO:0043025 | inferred from direct assay "ta, anon-WO0149856.3, Pal1, CG12130, PAL1, dPAL1, DPAL1" "IPR000720:Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase, IPR013017:NHL repeat, subgroup, IPR011042:Six-bladed beta-propeller, TolB-like, IPR001258:NHL repeat" CG12130 11-Aug-17 DroID_v2017_08 Drer\pam - "Cele\pgal-1, Cele\pamn-1, Cele\nhl-1, Cele\pghm-1" Xtro\pam "Mmus\Pam, Mmus\Nhlrc3" "Hsap\PAM, Hsap\NHLRC3" "viable,reduced,visible,female fertile,male sterile,dominant,behavior defective,poor,lethal,recessive" "wing,wing vein" FBgn0035022 CG11413 - http://flybase.org/reports/FBgn0035022 protein_coding_gene - - - "CT31865, BcDNA:RH33060, CG11413" - CG11413 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0069185 mcl(2)Z0193 mcl(2)Z0193 http://flybase.org/reports/FBgn0069185 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z0193 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0264297 CG43775 - http://flybase.org/reports/FBgn0264297 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG43775, CG13569, CG13569-1" "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG43775 11-Aug-17 DroID_v2017_08 "Drer\crispld1a, Drer\crispld2, Drer\r3hdml, Drer\LOC100536500, Drer\pi15b, Drer\glipr1b, Drer\glipr2l, Drer\crispld1b, Drer\glipr2, Drer\pi15a" "Scer\PRY3, Scer\PRY1, Scer\PRY2" "Cele\lon-1, Cele\scl-23, Cele\scl-10, Cele\vap-1, Cele\vap-2" "Xtro\crisp3, Xtro\glipr2, Xtro\crisp2, Xtro\MGC108118, Xtro\r3hdml, Xtro\crisp1, Xtro\crispld2" "Mmus\Clec18a, Mmus\Crispld2, Mmus\Glipr1l2, Mmus\Pi16, Mmus\Crisp3, Mmus\Crisp1, Mmus\R3hdml, Mmus\Crisp4, Mmus\Crisp2, Mmus\Glipr1, Mmus\Glipr2, Mmus\Glipr1l1, Mmus\Crispld1, Mmus\Pi15" "Hsap\CLEC18B, Hsap\PI15, Hsap\GLIPR2, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\CRISPLD2, Hsap\R3HDML, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\PI16, Hsap\CLEC18A, Hsap\CRISPLD1, Hsap\GLIPR1, Hsap\CRISP2" viable FBgn0065802 l(2)SH0404 lethal (2) SH0404 http://flybase.org/reports/FBgn0065802 gene - - - l(2)SH0404 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003934 snRNA:U5:23D small nuclear RNA U5 at 23DE http://flybase.org/reports/FBgn0003934 FBgn0003932 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-23D, snRNA[[3]], K2, dU5, snRNA:U5:23DE, snRNA:U5, snRNA4, snRNA3, U5snRNA23DE, CR32999, U5snRNA, snRNA:U5:23D, U5:23D, U5 snRNA, U5 snRNA 23D" - CR32999 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266072 CR44825 - http://flybase.org/reports/FBgn0266072 non_protein_coding_gene - - - CR44825 - CR44825 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065912 l(2)SH0177 lethal (2) SH0177 http://flybase.org/reports/FBgn0065912 gene - - - "l(2)SH0177, l(2)SH2 0177" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035715 CG10103 - http://flybase.org/reports/FBgn0035715 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR005061 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from sequence or structural similarity with SGD:S000005209 endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000005209 CG10103 IPR005061:Vacuolar protein sorting-associated protein Ist1 CG10103 11-Aug-17 DroID_v2017_08 Drer\ist1 Scer\IST1 Cele\istr-1 "Xtro\LOC100216037, Xtro\ist1" Mmus\Ist1 Hsap\IST1 viable FBgn0265487 mbl muscleblind http://flybase.org/reports/FBgn0265487 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 nucleic acid binding ; GO:0003676 | non-traceable author statement DNA binding ; GO:0003677 | traceable author statement "apoptotic process ; GO:0006915 | inferred from direct assay regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys embryo development ; GO:0009790 | inferred from mutant phenotype regulation of female receptivity ; GO:0045924 | non-traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | traceable author statement compound eye photoreceptor cell differentiation ; GO:0001751 | traceable author statement" cytoplasm ; GO:0005737 | inferred from direct assay H zone ; GO:0031673 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "mbl, Mbl, mbn, chst, mm, CG14477, n(2)k07110, l(2)k01212, l(2)01038, l(2)k05507, CG10941, CG33197, chaste, cht, BG01127, mb1" "IPR000571:Zinc finger, CCCH-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG33197 11-Aug-17 DroID_v2017_08 "Drer\mbnl1, Drer\mbnl3, Drer\zc3h10, Drer\mbnl2" - "Cele\Y53G8AR.9, Cele\mbl-1" "Xtro\mbnl2, Xtro\zc3h10, Xtro\mbnl1, Xtro\mbnl3" "Mmus\Zc3h10, Mmus\Mbnl2, Mmus\Mbnl1, Mmus\Mbnl3" "Hsap\MBNL3, Hsap\MBNL2, Hsap\MBNL1, Hsap\ZC3H10" larval stage eye disc

larval stage " early ommatidial precursor cluster

, imaginal disc

" FBgn0060740 l(3)S066619b lethal (3) S066619b http://flybase.org/reports/FBgn0060740 gene - - - "0666/19, l(3)S066619b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034099 CG15708 - http://flybase.org/reports/FBgn0034099 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 - - CG15708 "IPR006629:LPS-induced tumour necrosis factor alpha factor, IPR003656:Zinc finger, BED-type" CG15708 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262751 Mst77Y-2 Male-specific transcript 77Y 2 http://flybase.org/reports/FBgn0262751 nuclear_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F Mst77Y-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030280 CG11106 - http://flybase.org/reports/FBgn0030280 protein_coding_gene - - - "BcDNA:AT24116, CG11106" - CG11106 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19381 K 0.412976335 -0.065854499 0.080563275 -0.196760164 1.690240472 0.224836486 FBgn0001725 l(1)ESHS46 lethal (1) ESHS46 http://flybase.org/reports/FBgn0001725 - gene - - - l(1)ESHS46 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034939 thoc5 thoc5 http://flybase.org/reports/FBgn0034939 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000332618 "cell proliferation ; GO:0008283 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000332618 positive regulation of DNA-templated transcription, elongation ; GO:0032786 | inferred from biological aspect of ancestor with PANTHER:PTN000332618 male meiosis ; GO:0007140 | inferred from mutant phenotype mRNA export from nucleus in response to heat stress ; GO:0031990 | inferred by curator from GO:0000347 response to heat ; GO:0009408 | inferred from mutant phenotype" "THO complex part of transcription export complex ; GO:0000445 | inferred from biological aspect of ancestor with PANTHER:PTN000332618 protein complex ; GO:0043234 | inferred from physical interaction with thoc7, Hpr1 nuclear chromosome ; GO:0000228 | colocalizes_with inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:19074 nucleolus ; GO:0005730 | colocalizes_with inferred from direct assay THO complex ; GO:0000347 | inferred from direct assay" "THOC5, CG2980, thoc5, Thoc5, garm" "IPR019163:THO complex, subunit 5" CG2980 11-Aug-17 DroID_v2017_08 Drer\thoc5 - Cele\Y32H12A.2 Xtro\thoc5 Mmus\Thoc5 Hsap\THOC5 "male sterile,recessive,female fertile,viable" "nucleolus,condensed nuclear chromosome,spermatid" FBgn0034478 CG10822 - http://flybase.org/reports/FBgn0034478 protein_coding_gene "dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from sequence or structural similarity CG10822 IPR004942:Roadblock/LAMTOR2 domain CG10822 11-Aug-17 DroID_v2017_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb2, Mmus\Dynlrb1" "Hsap\DYNLRB2, Hsap\DYNLRB1" "viable,body color defective" mesothoracic tergum FBgn0086284 GS8172 - http://flybase.org/reports/FBgn0086284 gene - - - "GS8172, 8172" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023216 Parg Poly(ADP-ribose) glycohydrolase http://flybase.org/reports/FBgn0023216 - protein_coding_gene poly(ADP-ribose) glycohydrolase activity ; GO:0004649 | inferred from electronic annotation with InterPro:IPR007724 response to heat ; GO:0009408 | inferred from mutant phenotype maintenance of protein location in nucleus ; GO:0051457 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype regulation of histone acetylation ; GO:0035065 | inferred from mutant phenotype regulation of RNA splicing ; GO:0043484 | inferred from mutant phenotype Cajal body organization ; GO:0030576 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype carbohydrate metabolic process ; GO:0005975 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "PARG, EG:114E2.1, CG2864, Parg, parg, HD10914" IPR007724:Poly(ADP-ribose) glycohydrolase CG2864 11-Aug-17 DroID_v2017_08 "Drer\parga, Drer\pargb" - "Cele\parg-2, Cele\parg-1" Xtro\parg Mmus\Parg "Hsap\BPHL, Hsap\PARG" "visible,partially lethal - majority die,cold sensitive,short lived,sterile,neuroanatomy defective,melanotic mass phenotype,lethal,partially,heat stress response defective,viable" "dorsocentral bristle,scutellar bristle,ectopic,microchaeta,wing,mesothoracic leg,neuron & nucleus & adult,oocyte,cell non-autonomous,germline clone,somatic clone,female germline stem cell,Cajal body,histone locus body,nucleolusda.G32" FBgn0266310 CR44975 - http://flybase.org/reports/FBgn0266310 non_protein_coding_gene - - - CR44975 - CR44975 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031088 CG15322 - http://flybase.org/reports/FBgn0031088 protein_coding_gene - - - CG15322 - CG15322 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032122 CG31883 - http://flybase.org/reports/FBgn0032122 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG17022, anon-WO0140519.218, CG31883" - CG31883 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005092 fs(2)OWc4 female sterile (2) OWc4 http://flybase.org/reports/FBgn0005092 - gene - - - fs(2)OWc4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058343 CG40343 - http://flybase.org/reports/FBgn0058343 protein_coding_gene - - - CG40343 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267693 CR46029 - http://flybase.org/reports/FBgn0267693 non_protein_coding_gene - - - CR46029 - CR46029 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000651 febB feeding behavior B http://flybase.org/reports/FBgn0000651 - gene - - - febB - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,behavior defective,recessive,feeding behavior defective,somatic clone" FBgn0031826 CG9550 - http://flybase.org/reports/FBgn0031826 protein_coding_gene N-acetylglucosamine 6-O-sulfotransferase activity ; GO:0001517 | inferred from biological aspect of ancestor with PANTHER:PTN000842280 sulfur compound metabolic process ; GO:0006790 | inferred from biological aspect of ancestor with PANTHER:PTN001322541 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001322541 "CG9550, d6ST2" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000863:Sulfotransferase domain" CG9550 11-Aug-17 DroID_v2017_08 "Drer\zgc:194879, Drer\chst2b, Drer\chst3b, Drer\chst2a, Drer\chst1, Drer\chst7, Drer\chst3a, Drer\si:ch73-62b13.1" - - "Xtro\chst1, Xtro\chst4, Xtro\chst2, Xtro\chst7, Xtro\chst6, Xtro\chst3" "Mmus\Chst5, Mmus\Chst7, Mmus\Chst1, Mmus\Chst4, Mmus\Chst3, Mmus\Chst2" "Hsap\CHST7, Hsap\CHST4, Hsap\CHST1, Hsap\CHST3, Hsap\CHST5, Hsap\CHST6, Hsap\CHST2" viable FBgn0030777 CG9672 - http://flybase.org/reports/FBgn0030777 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000669108 "SPH161, BcDNA:GH16384, CG9672" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG9672 11-Aug-17 DroID_v2017_08 "Drer\proca, Drer\si:ch211-165b19.9, Drer\si:dkey-21e2.3, Drer\gzm3, Drer\proza, Drer\gzma, Drer\LOC558805, Drer\si:dkey-21e2.16, Drer\zgc:171509, Drer\zgc:163025, Drer\si:ch211-165b19.8, Drer\prozb, Drer\gzmk" - - - "Mmus\Klk12, Mmus\Proc, Mmus\Proz" "Hsap\PROC, Hsap\PROZ" viable FBgn0011167 l(1)DM-4 lethal (1) DM-4 http://flybase.org/reports/FBgn0011167 FBgn0010204 gene - - - l(1)DM-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003243 rfr refringent http://flybase.org/reports/FBgn0003243 - gene - oogenesis ; GO:0048477 | traceable author statement - "ref, rfr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,visible,viable,male,male fertile,female,reduced" wing FBgn0034942 CG13566 - http://flybase.org/reports/FBgn0034942 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13566 - CG13566 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC04203 I -1.617712005 -1.058909333 -0.100310023 0.839259811 0.769476694 0.777256016 FBgn0026873 MED18 Mediator complex subunit 18 http://flybase.org/reports/FBgn0026873 - protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | contributes_to inferred by curator from GO:0016592 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR019095 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred by curator from GO:0016592 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype termination of RNA polymerase II transcription ; GO:0006369 | inferred from biological aspect of ancestor with PANTHER:PTN001410513 core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN001410513 nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from direct assay "CG14802, Med18, p28/CG14802, Srb5/Med28b, dp28b, EG:63B12.13, p28, MED18" "IPR019095:Mediator complex, subunit Med18, metazoa/fungi" CG14802 11-Aug-17 DroID_v2017_08 Drer\med18 Scer\SRB5 Cele\mdt-18 Xtro\med18 Mmus\Med18 Hsap\MED18 "cell growth defective,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,chaeta,supernumerary" FBgn0025356 Src64B::tub Src64B::tub http://flybase.org/reports/FBgn0025356 - engineered_fusion_gene - - - "src-tube, Src64B::tub" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020566 anon-88Ad anon-88Ad http://flybase.org/reports/FBgn0020566 - gene - - - anon-88Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001521 l(1)11Ae lethal (1) 11Ae http://flybase.org/reports/FBgn0001521 - gene - - - "l(1)L2, 2, l(1)11Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259990 CG42487 - http://flybase.org/reports/FBgn0259990 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42487 - CG42487 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030871 CG8142 - http://flybase.org/reports/FBgn0030871 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000186208 cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 Elg1 RFC-like complex ; GO:0031391 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG8142, RfC, DmRFC2, RFC2, Rfc37" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR013748:Replication factor C, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8142 11-Aug-17 DroID_v2017_08 "Drer\rfc4, Drer\rfc2, Drer\rfc5" Scer\RFC2 "Cele\rfc-2, Cele\F44B9.8, Cele\rfc-4" "Xtro\rfc2, Xtro\rfc5, Xtro\rfc4" "Mmus\Rfc2, Mmus\Rfc5, Mmus\Rfc4" "Hsap\RFC2, Hsap\RFC4, Hsap\RFC5" "viable,fertile,visible" "chaeta,trichogen cell" FBgn0039387 MCO3 multicopper oxidase 3 http://flybase.org/reports/FBgn0039387 protein_coding_gene "copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR002355, InterPro:IPR011706, InterPro:IPR011707 iron ion transmembrane transporter activity ; GO:0005381 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001709969 ferroxidase activity ; GO:0004322 | inferred from biological aspect of ancestor with PANTHER:PTN001709969" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001117, InterPro:IPR011706 iron ion transport ; GO:0006826 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 iron assimilation by reduction and transport ; GO:0033215 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 copper ion homeostasis ; GO:0055070 | inferred from direct assay" high-affinity iron permease complex ; GO:0033573 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 "MCO3, CG5959, MIP26036" "IPR001117:Multicopper oxidase, type 1, IPR002355:Multicopper oxidase, copper-binding site, IPR008972:Cupredoxin, IPR011706:Multicopper oxidase, type 2, IPR011707:Multicopper oxidase, type 3, IPR033138:Multicopper oxidases, conserved site" CG5959 11-Aug-17 DroID_v2017_08 "Drer\cp, Drer\hephl1b" "Scer\GMC1, Scer\FET3, Scer\FET5" Cele\F21D5.3 Xtro\hephl1 "Mmus\Heph, Mmus\Hephl1, Mmus\Cp" "Hsap\CP, Hsap\HEPHL1, Hsap\HEPH" "viable,fertile" FBgn0262103 Sik3 Salt-inducible kinase 3 http://flybase.org/reports/FBgn0262103 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:21680 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cellular response to hormone stimulus ; GO:0032870 | inferred from biological aspect of ancestor with PANTHER:PTN001552066 protein phosphorylation ; GO:0006468 | non-traceable author statement lipid homeostasis ; GO:0055088 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:21680 response to starvation ; GO:0042594 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 "CG15072, SIK, SIK3, Sik3, CG42856, EMK/KIAA0999, CG18604" "IPR028375:KA1 domain/Ssp2, C-terminal, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR001772:Kinase associated domain 1 (KA1)" CG42856 11-Aug-17 DroID_v2017_08 "Drer\sik2b, Drer\mark4a, Drer\mark3a, Drer\zgc:66101, Drer\mark3b, Drer\prkaa1, Drer\mark1, Drer\mark2a, Drer\mark2b, Drer\si:dkey-31m14.7, Drer\sik1, Drer\sik2a" "Scer\KIN2, Scer\SNF1, Scer\KIN1, Scer\PRR1" "Cele\par-1, Cele\kin-29" "Xtro\sik3, Xtro\prkaa1, Xtro\mark4, Xtro\mark2, Xtro\mark3, Xtro\sik2, Xtro\prkaa2" "Mmus\Gm6729, Mmus\Prkaa1, Mmus\Smok3b, Mmus\Gm6882, Mmus\Gm7168, Mmus\Smok2a, Mmus\1810024B03Rik, Mmus\Gm14147, Mmus\Sik1, Mmus\Mark4, Mmus\Gm4922, Mmus\Sik2, Mmus\Gm6902, Mmus\Prkaa2, Mmus\4921509C19Rik, Mmus\Gm6176, Mmus\Gm10668, Mmus\Mark3, Mmus\Mark2, Mmus\Gm14151, Mmus\Smok2b, Mmus\Gm5174, Mmus\Mark1, Mmus\Smok3a, Mmus\Sik3" "Hsap\SIK2, Hsap\SIK1, Hsap\MARK1, Hsap\SIK3, Hsap\MARK4, Hsap\PRKAA1, Hsap\MARK3, Hsap\PRKAA2, Hsap\MARK2" FBgn0021774 ms(2)985 ms(2)985 http://flybase.org/reports/FBgn0021774 - gene - - - "ms-985, ms(2)985" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,viable" FBgn0083285 E(smoDN)2135 Enhancer of smoDN 2135 http://flybase.org/reports/FBgn0083285 gene - - - E(smoDN)2135 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250897 zaa43d06 - http://flybase.org/reports/FBgn0250897 gene - - - "zaa43d06, zaa43d06x1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015563 vivi-repeat vivi-repeat http://flybase.org/reports/FBgn0015563 FBgn0025236 repeat_region - - - "Vivi, HP1-VS, VS, anon-EST:fe2A2, vivi-repeat" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034210 CG6568 - http://flybase.org/reports/FBgn0034210 protein_coding_gene - - - CG6568 - CG6568 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-56d12.4, Drer\zgc:113019, Drer\si:dkey-60a16.1" - - - - - viable FBgn0020255 Ran Ran http://flybase.org/reports/FBgn0020255 "FBgn0026685, FBgn0030273" protein_coding_gene GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 protein binding ; GO:0005515 | inferred from physical interaction with cno GTP binding ; GO:0005525 | inferred from direct assay GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000005711 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W1A4 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002041 actin filament organization ; GO:0007015 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype inferred from genetic interaction with dlg1 inferred from genetic interaction with cno regulation of mitotic cell cycle ; GO:0007346 | inferred from direct assay protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern cell cycle ; GO:0007049 | inferred from direct assay regulation of protein localization ; GO:0032880 | inferred from mutant phenotype protein export from nucleus ; GO:0006611 | inferred from sequence or structural similarity with HGNC:9846 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype ribosomal subunit export from nucleus ; GO:0000054 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 intracellular protein transport ; GO:0006886 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay nuclear microtubule ; GO:0005880 | inferred from direct assay "Ran, AAF30287, CG1404, ran10A, dran, l(1)G0075, ran, Q9VZ23, RanGTP" "IPR002041:Ran GTPase, IPR005225:Small GTP-binding protein domain, IPR001806:Small GTPase superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1404 11-Aug-17 DroID_v2017_08 Drer\ran "Scer\GSP1, Scer\GSP2" Cele\ran-1 Xtro\ran "Mmus\1700009N14Rik, Mmus\Rasl2-9, Mmus\Ran" Hsap\RAN embryonic stage organism

"viable,wild-type,female sterile,male sterile,lethal,fertile,partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,visible,lethal - all die before end of larval stage,some die during larval stage" "karyosome,meiotic spindlenos.UTR.THsimVP16,ommatidium,photoreceptor cell,photoreceptor cell R7,cone cell,pigment cell" DRSC20364 I -1.583757533 0.054210938 -1.360761974 -0.590233519 0.303333163 0.629600729 FBgn0050021 metro menage a trois http://flybase.org/reports/FBgn0050021 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype subsynaptic reticulum ; GO:0071212 | inferred from direct assay "CG18338, CG13219, CG30021, Metro, metro, skf, FBgn0050021, skiff" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001452:SH3 domain, IPR001478:PDZ domain, IPR004172:L27 domain, IPR008144:Guanylate kinase-like domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR011511:Variant SH3 domain, IPR020590:Guanylate kinase, conserved site" CG30021 11-Aug-17 DroID_v2017_08 "Drer\LOC556594, Drer\si:ch73-272h16.4, Drer\mpp3a, Drer\caska, Drer\mpp3b, Drer\mpp5b, Drer\mpp2b, Drer\mpp5a, Drer\mpp6a, Drer\mpp1, Drer\mpp4a, Drer\mpp7a, Drer\mpp2a, Drer\mpp7b, Drer\mpp6b" Scer\GUK1 "Cele\magu-1, Cele\lin-2, Cele\magu-2" "Xtro\mpp2, Xtro\mpp6, Xtro\cask, Xtro\mpp1, Xtro\mpp7, Xtro\mpp5" "Mmus\Mpp5, Mmus\Mpp3, Mmus\Cask, Mmus\Mpp7, Mmus\Mpp6, Mmus\Mpp2, Mmus\Mpp1, Mmus\Mpp4" "Hsap\MPP4, Hsap\MPP3, Hsap\CASK, Hsap\MPP7, Hsap\MPP1, Hsap\MPP6, Hsap\MPP2, Hsap\MPP5" "viable,fertile,neuroanatomy defective" neuromuscular junction FBgn0086666 snoRNA:Psi28S-2179 snoRNA:Psi28S-2179 http://flybase.org/reports/FBgn0086666 snoRNA_gene - - - "snoRNA:734, psi28S-2179, Dm-734, snoR734, CR33918, Psi28S-2719(SnoR734), SnoR734, Psi28S-2719, snoRNA:Psi28S-2179" - CR33918 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015918 cant cat of nine tails http://flybase.org/reports/FBgn0015918 - gene - - - cant - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086392 BG02053 - http://flybase.org/reports/FBgn0086392 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02053 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0000386 ctt contorted http://flybase.org/reports/FBgn0000386 - gene - - - ctt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,female sterile,male fertile" "wing,eye,macrochaeta,anterior orbital bristle,middle orbital bristle,posterior orbital bristle,genitalia,male,orbital bristle,male genitalia" FBgn0014378 raz razorback http://flybase.org/reports/FBgn0014378 - gene - - - raz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015554 ttp tip-tap http://flybase.org/reports/FBgn0015554 - gene - - - ttp - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001350 l(1)1Ee lethal (1) 1Ee http://flybase.org/reports/FBgn0001350 - gene - - - l(1)1Ee - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265946 CR44733 - http://flybase.org/reports/FBgn0265946 non_protein_coding_gene - - - CR44733 - CR44733 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069224 gl(2R)18-14 gl(2R)18-14 http://flybase.org/reports/FBgn0069224 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2R)18-14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,embryonic head,denticle belt" FBgn0001323 knrl knirps-like http://flybase.org/reports/FBgn0001323 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628" "open tracheal system development ; GO:0007424 | traceable author statement regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay regulation of tube size, open tracheal system ; GO:0035151 | traceable author statement branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001628 "Knrl, NR0A2, CG4761, knrl, knl" "IPR001628:Zinc finger, nuclear hormone receptor-type, IPR013088:Zinc finger, NHR/GATA-type" CG4761 11-Aug-17 DroID_v2017_08 - - "Cele\nhr-119, Cele\nhr-3, Cele\nhr-85, Cele\nhr-7" - - Hsap\NR1H2 " embryonic stage | cellular blastoderm , embryonic stage , larval stage , embryonic stage | embryonic cycle 12 , larval stage | third instar , embryonic stage | 70% egg length , organism | 80-100% egg length & ventral

, wing vein L2 | precursor

,

ubiquitous , organism | 20-30% egg length

" "mitotic cell cycle defective,visible,viable" "dorsal closure embryo,embryonic dorsal epidermis,metathoracic femur,adult thorax & macrochaetaBx-MS1096" FBgn0263909 l(3)B57 - http://flybase.org/reports/FBgn0263909 gene - - - l(3)B57 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0045968 Tabor\pol Tabor element pol http://flybase.org/reports/FBgn0045968 transposable_element_gene - - - "ORF2, Pilgrim\pol, Tabor\pol" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003309 sable sable http://flybase.org/reports/FBgn0003309 - gene - developmental pigmentation ; GO:0048066 | traceable author statement developmental pigmentation ; GO:0048066 | non-traceable author statement - "eb, s, sable" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,body color defective,female sterile,viable,male,male fertile" "wing,scutellum,trident" FBgn0267928 CR46209 - http://flybase.org/reports/FBgn0267928 non_protein_coding_gene - - - "CR46209, lincRNA.196" - CR46209 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067882 Mod(Prat:bw)1-5 Mod(Prat:bw)1-5 http://flybase.org/reports/FBgn0067882 gene - - - "Mod-1-5, Mod(Prat:bw)1-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - enhancer of variegation FBgn0038965 mats mob as tumor suppressor http://flybase.org/reports/FBgn0038965 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NBK5 protein kinase binding ; GO:0019901 | inferred from physical interaction with trc protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VA38 apoptotic process ; GO:0006915 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype mitotic spindle checkpoint ; GO:0071174 | NOT inferred from mutant phenotype multicellular organism development ; GO:0007275 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG13852, anon-WO0118547.303, mats, Mats, DMob1, dmob1, Dmob1, Mob1" IPR005301:MOB kinase activator family CG13852 11-Aug-17 DroID_v2017_08 "Drer\mob2b, Drer\mob3c, Drer\mob2a, Drer\mob3a, Drer\mob1a, Drer\mob1ba, Drer\LOC799520, Drer\mob1bb" "Scer\MOB1, Scer\MOB2" "Cele\F38H4.10, Cele\T12B3.4" "Xtro\mob2.1, Xtro\mob3a, Xtro\mob3c, Xtro\mob2.2, Xtro\mob1a, Xtro\mob1b, Xtro\mob3b" "Mmus\Mob1a, Mmus\Mob1b, Mmus\Mob3b, Mmus\Mob3c, Mmus\Mob2, Mmus\Mob3a" "Hsap\MOB3C, Hsap\MOB2, Hsap\MOB3B, Hsap\MOB3A, Hsap\MOB1B, Hsap\MOB1A" "neuroanatomy defective,somatic clone,tumorigenic,dominant,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal,visible,body color defective,viable,wild-type,mitotic cell cycle defective" "imaginal disc,adult mushroom body,somatic clone,humerus,anepisternum,denticle,wing,wing hair,supernumerary,trichogen cell,mesothoracic tergum" DRSC14702 K 0.085228639 0.658521368 0.285839586 0.376705118 -0.522239165 3.279516468 FBgn0266777 CR45242 - http://flybase.org/reports/FBgn0266777 non_protein_coding_gene - - - CR45242 - CR45242 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013932 E(DTW) E(DTW) http://flybase.org/reports/FBgn0013932 - gene - - - E(DTW) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085662 CG41517 - http://flybase.org/reports/FBgn0085662 protein_coding_gene - - - CG41517 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031108 CG15459 - http://flybase.org/reports/FBgn0031108 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial proton-transporting ATP synthase complex ; GO:0005753 | inferred from biological aspect of ancestor with PANTHER:PTN002145699 CG15459 - CG15459 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-80c12.10 - - - Mmus\Usmg5 Hsap\USMG5 FBgn0262683 CG43153 - http://flybase.org/reports/FBgn0262683 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43153, lincRNA.110" - CG43153 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004852 Ac76E Adenylyl cyclase 76E http://flybase.org/reports/FBgn0004852 - protein_coding_gene guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 adenylate cyclase activity ; GO:0004016 | non-traceable author statement adenylate cyclase activity ; GO:0004016 | inferred from direct assay "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 response to starvation ; GO:0042594 | inferred from direct assay instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cAMP biosynthetic process ; GO:0006171 | inferred from direct assay negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG7978, AC 76E, DAC76E, DAC2, Ac76E, ac76e, AC76E" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase, IPR032628:Adenylate cyclase, N-terminal" CG7978 11-Aug-17 DroID_v2017_08 "Drer\adcy2b, Drer\adcy1a, Drer\adcy7, Drer\adcy2a, Drer\adcy1b, Drer\adcy6b, Drer\adcy3a, Drer\adcy8, Drer\adcy6a, Drer\adcy5, Drer\si:dkey-206f10.1, Drer\si:ch211-132f19.7" - "Cele\acy-2, Cele\acy-4" "Xtro\dnajc27, Xtro\adcy1, Xtro\adcy6, Xtro\adcy4, Xtro\adcy7" "Mmus\Adcy5, Mmus\Adcy2, Mmus\Adcy7, Mmus\Adcy6, Mmus\Adcy3, Mmus\Adcy4, Mmus\Adcy8, Mmus\Adcy1" "Hsap\ADCY1, Hsap\ADCY8, Hsap\ADCY3, Hsap\ADCY7, Hsap\ADCY5, Hsap\ADCY6, Hsap\ADCY2, Hsap\ADCY4" "developmental rate defective,body size defective,starvation stress response defective,female limited" FBgn0010072 Mab66B2 Monoclonal antibody 66B2 http://flybase.org/reports/FBgn0010072 - gene - - - Mab66B2 - - 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage , embryonic stage | 12-15 hr , pupal stage , embryonic stage " " imaginal disc

, embryonic/larval hindgut

, optic lobe

, epidermis

, neuropil

, central nervous system

, embryonic/larval foregut

, embryonic/larval trachea

, Keilin's organ

" FBgn0039876 CG2126 - http://flybase.org/reports/FBgn0039876 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from sequence or structural similarity with HGNC:20184 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from sequence or structural similarity with HGNC:20184 cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.412, CG2126" IPR008485:Protein of unknown function DUF766 CG2126 11-Aug-17 DroID_v2017_08 Drer\jkamp - Cele\jamp-1 Xtro\jkamp "Mmus\4931417E11Rik, Mmus\Jkamp" Hsap\JKAMP viable DRSC15418 E 0.863364304 0.056081719 -0.335910605 -2.634622219 1.088719498 -1.103259431 FBgn0022089 l(2)k07315 lethal (2) k07315 http://flybase.org/reports/FBgn0022089 - gene - - - l(2)k07315 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005087 fs(2)OW811 female sterile (2) OW811 http://flybase.org/reports/FBgn0005087 - gene - - - fs(2)OW811 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061483 rover\gag rover element gag http://flybase.org/reports/FBgn0061483 transposable_element_gene - - - rover\gag - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000933 fs(2)A3 female sterile (2) A3 http://flybase.org/reports/FBgn0000933 - gene - - - fs(2)A3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0032562 CG18483 - http://flybase.org/reports/FBgn0032562 protein_coding_gene - - - "Ms(2)35Ci, BG:DS07851.10, CG18483" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013484 l(1)4Fb lethal (1) 4Fb http://flybase.org/reports/FBgn0013484 - gene - - - l(1)4Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065372 l(2)SH1694 lethal (2) SH1694 http://flybase.org/reports/FBgn0065372 gene - - - "l(2)SH1694, l(2)SH2 1694" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004758 l(3)89Bk lethal (3) 89Bk http://flybase.org/reports/FBgn0004758 - gene - - - l(3)89Bk - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014148 dkn deathknell http://flybase.org/reports/FBgn0014148 - gene - - - dkn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041091 ubi-d4 ubi-d4 http://flybase.org/reports/FBgn0041091 gene - - - ubi-d4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001508 l(1)10Fb lethal (1) 10Fb http://flybase.org/reports/FBgn0001508 - gene - - - l(1)10Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "ovariole,germline clone,egg" FBgn0013516 l(1)XWJ lethal (1) XWJ http://flybase.org/reports/FBgn0013516 - gene - - - "XWJ, l(1)XWJ" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001916 l(2)25Bc lethal (2) 25Bc http://flybase.org/reports/FBgn0001916 - gene - - - "jf12, l(2)jf12, l(2)25Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000753 fs(1)A426 female sterile (1) A426 http://flybase.org/reports/FBgn0000753 - gene - - - fs(1)A426 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,heat sensitive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" embryo FBgn0036937 Ir76b Ionotropic receptor 76b http://flybase.org/reports/FBgn0036937 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 sodium channel activity ; GO:0005272 | inferred from direct assay salty taste receptor activity ; GO:0033039 | inferred from mutant phenotype olfactory receptor activity ; GO:0004984 | contributes_to inferred from direct assay ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model transmission of nerve impulse ; GO:0019226 | inferred from mutant phenotype cellular response to salt ; GO:1902075 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a salt aversion ; GO:0035199 | NOT inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 sensory dendrite ; GO:0071683 | inferred from direct assay receptor complex ; GO:0043235 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "Ir76b, CT22733, IR76b, CG7385, DmelIR76b, ir76b" IPR001320:Ionotropic glutamate receptor CG7385 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,chemosensitive behavior defective,viable" "L-type sensilla L6,L-type sensilla L4,L-type sensilla L2" FBgn0265422 CR44334 - http://flybase.org/reports/FBgn0265422 non_protein_coding_gene - - - CR44334 - CR44334 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046117 E(To)9 E(To)9 http://flybase.org/reports/FBgn0046117 gene - - - E(To)9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,recessive,viable,visible" "dorsal appendage,eye,wing margin" FBgn0265640 CR44447 - http://flybase.org/reports/FBgn0265640 non_protein_coding_gene - - - CR44447 - CR44447 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263031 CG43326 - http://flybase.org/reports/FBgn0263031 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13514, CG30217, CG43326" IPR006629:LPS-induced tumour necrosis factor alpha factor CG43326 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040787 CG12518 - http://flybase.org/reports/FBgn0040787 protein_coding_gene - - - CG12518 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022088 l(2)k07332 lethal (2) k07332 http://flybase.org/reports/FBgn0022088 - gene - - - l(2)k07332 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002911 mwg micro-wing http://flybase.org/reports/FBgn0002911 - gene - - - mwg - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,fertile,viable" "wing,haltere" FBgn0084004 CG41437 - http://flybase.org/reports/FBgn0084004 protein_coding_gene - - - CG41437 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062564 P10 P10 http://flybase.org/reports/FBgn0062564 gene - - - P10 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022110 l(2)k06918 lethal (2) k06918 http://flybase.org/reports/FBgn0022110 - gene - - - l(2)k06918 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039779 PH4alphaSG2 prolyl-4-hydroxylase-alpha SG2 http://flybase.org/reports/FBgn0039779 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG1546, PH4alphaSG2, SG2" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG1546 11-Aug-17 DroID_v2017_08 "Drer\p4ha2, Drer\p4ha1b, Drer\p4ha1a, Drer\p4ha3, Drer\zgc:158254, Drer\p4htm, Drer\zgc:152670" - "Cele\phy-2, Cele\phy-4, Cele\C14E2.4, Cele\Y43F8B.19, Cele\dpy-18, Cele\phy-3" "Xtro\p4ha1, Xtro\p4ha2, Xtro\p4ha3" "Mmus\P4ha1, Mmus\P4ha3, Mmus\P4htm, Mmus\P4ha2" "Hsap\P4HA3, Hsap\P4HA1, Hsap\P4HA2, Hsap\P4HTM" viable FBgn0036489 CG7011 - http://flybase.org/reports/FBgn0036489 protein_coding_gene molecular_function ; GO:0003674 | no biological data available ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000000040 - CG7011 "IPR012936:Endoplasmic reticulum vesicle transporter, C-terminal" CG7011 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-225b10.3, Drer\ergic1, Drer\ergic3, Drer\ergic2" "Scer\ERV41, Scer\ERV46" Cele\erv-46 "Xtro\ergic3, Xtro\ergic1, Xtro\ergic2" "Mmus\Ergic3, Mmus\Ergic2, Mmus\Ergic1" "Hsap\ERGIC1, Hsap\ERGIC3, Hsap\ERGIC2" viable FBgn0260630 f06222 - http://flybase.org/reports/FBgn0260630 gene - - - f06222 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045860 crle crippled leg http://flybase.org/reports/FBgn0045860 gene - - - crle - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004078 Ars-region13 Autonomous replicating sequence region 13 http://flybase.org/reports/FBgn0004078 - region - - - "Ars-region13, Ars13" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025687 LKRSDH Lysine ketoglutarate reductase/saccharopine dehydrogenase http://flybase.org/reports/FBgn0025687 "FBgn0031949, FBgn0045950" protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005097 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005097 regulation of histone methylation ; GO:0031060 | inferred from direct assay histone arginine methylation ; GO:0034969 | inferred from direct assay - "CG7144, BEST:CK02318, CK02318, anon-WO0149856.1, LKRSDH, LKR, dLKR, SDH" "IPR005097:Saccharopine dehydrogenase, NADP binding domain, IPR007698:Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain, IPR007886:Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal, IPR016040:NAD(P)-binding domain, IPR032095:Saccharopine dehydrogenase, C-terminal" CG7144 11-Aug-17 DroID_v2017_08 Drer\aass "Scer\LYS9, Scer\LYS1" Cele\R02D3.1 Xtro\aass Mmus\Aass Hsap\AASS pupal stage salivary gland

"viable,fertile" wing FBgn0038201 PK1-R Pyrokinin 1 receptor http://flybase.org/reports/FBgn0038201 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity inferred from direct assay pyrokinin receptor activity ; GO:0036401 | inferred from physical interaction with Capa neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype negative regulation of peptide hormone secretion ; GO:0090278 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "anon-WO0170980.113, anon-WO0170980.112, CG9918, PK1-R, Pk1r, Pk1R, pkr1" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG9918 11-Aug-17 DroID_v2017_08 "Drer\ghsrb, Drer\ntsr1, Drer\nmur3, Drer\LOC101885431, Drer\LOC101885494, Drer\LOC101885849, Drer\nmur1a, Drer\mlnr, Drer\nmur1b, Drer\ghsra, Drer\gpr39, Drer\LOC103910036" - "Cele\nmur-4, Cele\npr-32, Cele\nmur-1, Cele\nmur-2, Cele\nmur-3" Xtro\nmur2 "Mmus\Nmur2, Mmus\Gpr39, Mmus\Ghsr, Mmus\Ntsr2, Mmus\Nmur1, Mmus\Ntsr1" "Hsap\GHSR, Hsap\NTSR2, Hsap\GPR148, Hsap\NTSR1, Hsap\GPR39, Hsap\MLNR, Hsap\NMUR1, Hsap\NMUR2" "viable,fertile" FBgn0086417 l(3)CHa lethal (3) CHa http://flybase.org/reports/FBgn0086417 gene - - - l(3)CHa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004067 fs(2)mel1 female sterile (2) maternal effect lethal 1 http://flybase.org/reports/FBgn0004067 - gene - - - "mel 1, fs(2)mel1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "egg,maternal effect,embryo" FBgn0259713 CG42367 - http://flybase.org/reports/FBgn0259713 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31878, CG42367, CG4588" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG42367 11-Aug-17 DroID_v2017_08 Drer\mak Scer\IME2 Cele\fbxb-38 "Xtro\mak, Xtro\ick" "Mmus\Mak, Mmus\Ick, Mmus\Mok" "Hsap\MOK, Hsap\ICK, Hsap\MAK" "viable,fertile" FBgn0050020 CG30020 - http://flybase.org/reports/FBgn0050020 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG18353, CG12941, p190, BEST:LD40262, CG30020" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG30020 11-Aug-17 DroID_v2017_08 - Scer\RME1 - Xtro\sall1 "Mmus\Zfp580, Mmus\Zfp524" "Hsap\ZNF581, Hsap\ZNF524, Hsap\ZNF580" "viable,fertile" DRSC06730 K 1.032061316 0.017303785 0.417735398 -0.024358721 -1.79978409 -0.412861659 FBgn0085591 CG41274 - http://flybase.org/reports/FBgn0085591 protein_coding_gene - - - CG41274 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031452 Cwc25 Cwc25 http://flybase.org/reports/FBgn0031452 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "Cwc25, CG2843, CWC25" "IPR019339:CBF1-interacting co-repressor CIR, N-terminal domain, IPR022209:Pre-mRNA splicing factor" CG2843 11-Aug-17 DroID_v2017_08 Drer\cwc25 Scer\CWC25 Cele\mog-3 Xtro\cwc25 Mmus\Cwc25 Hsap\CWC25 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266005 CR44779 - http://flybase.org/reports/FBgn0266005 non_protein_coding_gene - - - CR44779 - CR44779 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083240 EP2204 EP2204 http://flybase.org/reports/FBgn0083240 gene - - - EP2204 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021986 l(2)k09801 lethal (2) k09801 http://flybase.org/reports/FBgn0021986 - gene - - - "P918, l(2)k09801" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041234 Gr59f Gustatory receptor 59f http://flybase.org/reports/FBgn0041234 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr59E1, CG5365, 59E.1, GR59E.1, CG33150, Gr59f" IPR013604:7TM chemoreceptor CG33150 11-Aug-17 DroID_v2017_08 "Drer\gstt2, Drer\gstt1b, Drer\gstr, Drer\mars, Drer\eef1g, Drer\vars, Drer\gstt1a, Drer\eef1e1" "Scer\CAM1, Scer\YGR201C, Scer\TEF4, Scer\GTT2, Scer\URE2, Scer\GTT1" - "Xtro\eef1e1, Xtro\eef1g, Xtro\gstt1" "Mmus\Gstt1, Mmus\Vars, Mmus\Gstt3, Mmus\Gstt4, Mmus\Gstt2, Mmus\Mars, Mmus\Eef1e1, Mmus\Eef1g" "Hsap\EEF1G, Hsap\GSTT2, Hsap\EEF1E1, Hsap\GSTT2B, Hsap\GSTT1, Hsap\MARS, Hsap\VARS" partially lethal - majority die FBgn0020581 anon-59Cd anon-59Cd http://flybase.org/reports/FBgn0020581 - gene - - - anon-59Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043026 l(2)42Fa lethal (2) 42Fa http://flybase.org/reports/FBgn0043026 gene - - - l(2)42Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266921 ft::Hsap\FAT4 - http://flybase.org/reports/FBgn0266921 engineered_fusion_gene - - - "ft::Hsap\FAT4, Fat:Fat4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031513 CG3347 - http://flybase.org/reports/FBgn0031513 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 - - CG3347 "IPR011011:Zinc finger, FYVE/PHD-type, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR001965:Zinc finger, PHD-type, IPR019786:Zinc finger, PHD-type, conserved site" CG3347 11-Aug-17 DroID_v2017_08 "Drer\bptf, Drer\cxxc1b, Drer\cxxc1a" "Scer\SPP1, Scer\CTI6" Cele\cfp-1 "Xtro\cxxc1, Xtro\bptf" "Mmus\Cxxc1, Mmus\Bptf, Mmus\Dido1" "Hsap\CXXC1, Hsap\DIDO1, Hsap\BPTF" viable DRSC00597 K 0.007647223 -0.538442014 -0.702709217 0.05744939 -0.050026463 1.621872587 FBgn0263960 BG01677 - http://flybase.org/reports/FBgn0263960 gene - - - BG01677 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,starvation stress response defective,male limited" FBgn0036812 Nufip Nufip http://flybase.org/reports/FBgn0036812 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000329871 box C/D snoRNP assembly ; GO:0000492 | inferred from biological aspect of ancestor with PANTHER:PTN000329871 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000329871 "CG4076, NUFIP, Nufip" "IPR019496:Nuclear fragile X mental retardation-interacting protein 1, conserved domain" CG4076 11-Aug-17 DroID_v2017_08 Drer\nufip1 - - Xtro\nufip1 Mmus\Nufip1 Hsap\NUFIP1 "viable,visible,lethal - all die before end of pupal stage" trichogen cell FBgn0052431 CG32431 - http://flybase.org/reports/FBgn0052431 protein_coding_gene - - - CG32431 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000796 fs(1)de7 female sterile (1) defective eggs 7 http://flybase.org/reports/FBgn0000796 - gene - - - "de7, fs(1)de7" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "dorsal appendage,chorion" FBgn0004505 fs(1)A5 female sterile (1) A5 http://flybase.org/reports/FBgn0004505 - gene - - - fs(1)A5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015454 l(2)24CDa lethal (2) 24CDa http://flybase.org/reports/FBgn0015454 - gene - - - "l(2)d, l(2)24CDa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039169 Spps Sp1-like factor for pairing sensitive-silencing http://flybase.org/reports/FBgn0039169 protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 polytene chromosome band ; GO:0005704 | inferred from direct assay "CG5669, Spps" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR032675:Leucine-rich repeat domain, L domain-like" CG5669 11-Aug-17 DroID_v2017_08 "Drer\sp3b, Drer\sp5a, Drer\klf11b, Drer\sp1, Drer\sp8a, Drer\klf5a, Drer\sp9, Drer\zeb1a, Drer\klf5l, Drer\zgc:153115, Drer\sp7, Drer\zgc:77358, Drer\sp8b, Drer\sp4, Drer\sp3a, Drer\sp5l, Drer\sp5b, Drer\sp2, Drer\klf13" "Scer\CRZ1, Scer\SWI5, Scer\ACE2" "Cele\ZK686.5, Cele\sptf-1, Cele\sptf-3, Cele\klf-2, Cele\sptf-2" "Xtro\sp3, Xtro\sp7, Xtro\sp5, Xtro\sp6, Xtro\sp1, Xtro\sp2, Xtro\sp5l, Xtro\sp4" "Mmus\Sp7, Mmus\Sp9, Mmus\Sp6, Mmus\Sp8, Mmus\Sp5, Mmus\Sp1, Mmus\Sp3, Mmus\Klf5, Mmus\Klf13, Mmus\Klf10, Mmus\Sp4, Mmus\Sp2" "Hsap\SP9, Hsap\SP4, Hsap\SP2, Hsap\SP5, Hsap\SP8, Hsap\KLF10, Hsap\SP3, Hsap\SP7, Hsap\SP6, Hsap\SP1, Hsap\KLF13" "lethal,recessive,germline clone,penetrance incomplete (obsolete FBcv0000019),partially lethal - majority die,lethal - all die before end of P-stage,some die during pharate adult stage,viable,visible" "wing,mesothoracic tergum" FBgn0003108 pallid pallid http://flybase.org/reports/FBgn0003108 - gene - - - "pl, pallid, pld" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority live,body color defective" wing FBgn0036814 CG14073 - http://flybase.org/reports/FBgn0036814 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - "Nirvana, CG14073" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG14073 11-Aug-17 DroID_v2017_08 "Drer\ankrd31, Drer\cdkn2c, Drer\bcor, Drer\bcorl1" "Scer\HOS4, Scer\YAR1" "Cele\frm-9, Cele\K02B12.5" "Xtro\bcor, Xtro\bcorl1" "Mmus\Cdkn2c, Mmus\Cdkn2d, Mmus\Bcorl1, Mmus\Bcor" "Hsap\BCORL1, Hsap\CDKN2D, Hsap\CDKN2C, Hsap\BCOR" viable FBgn0002463 l(3)SG16 lethal (3) SG16 http://flybase.org/reports/FBgn0002463 - gene - - - l(3)SG16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032817 CG10631 - http://flybase.org/reports/FBgn0032817 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612 - - CG10631 "IPR006612:Zinc finger, C2CH-type, IPR013087:Zinc finger C2H2-type" CG10631 11-Aug-17 DroID_v2017_08 "Drer\znf574, Drer\znf710a, Drer\znf366, Drer\znf710b" - "Cele\ztf-29, Cele\zag-1" - "Mmus\Zfp366, Mmus\Zfp710" "Hsap\ZNF710, Hsap\ZNF366" viable FBgn0019740 l(1)91-1 lethal (1) 91-1 http://flybase.org/reports/FBgn0019740 - gene - - - l(1)91-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259302 EP-108 - http://flybase.org/reports/FBgn0259302 gene - - - EP-108 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta" FBgn0044079 E(rst)H65 E(rst)H65 http://flybase.org/reports/FBgn0044079 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H65, E(rst)H65" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0267030 CR45474 - http://flybase.org/reports/FBgn0267030 non_protein_coding_gene - - - CR45474 - CR45474 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010243 Mst77F-PsiY1 Mst77F pseudogene on Y 1 http://flybase.org/reports/FBgn0010243 - pseudogene_attribute - - - "18c, Mst77F-PsiY1, Mst77-Psi1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030190 CG2908 - http://flybase.org/reports/FBgn0030190 protein_coding_gene - - - CG2908 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263851 snoRNA:CD-24 - http://flybase.org/reports/FBgn0263851 snoRNA_gene - - - "snoRNA:CD-24, snoCD_24, CR43712" - CR43712 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042697 N-fa-swb-INS Notch facet strawberry insulator element http://flybase.org/reports/FBgn0042697 insulator - - - "Fa[swb], fa[swb], N-fa-swb-INS" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005465 l(1)ts88 lethal (1) ts88 http://flybase.org/reports/FBgn0005465 - gene - - - l(1)ts88 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0031145 Ntf-2 Nuclear transport factor-2 http://flybase.org/reports/FBgn0031145 protein_coding_gene - transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR002075 positive regulation of antimicrobial peptide biosynthetic process ; GO:0002807 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR002075 "DNTF-2, NTF-2, ntf2, Dntf-2, Dntf2, CG1740, dmNTF2, l(1)G0086, l(1)G0125, l(1)G0428, l(1)G0337, BcDNA:GM08921, Ntf-2, ntf-2, Ntf2" "IPR018222:Nuclear transport factor 2, eukaryote, IPR002075:Nuclear transport factor 2, IPR032710:NTF2-like domain" CG1740 11-Aug-17 DroID_v2017_08 "Drer\nutf2, Drer\nutf2l" Scer\NTF2 Cele\ran-4 Xtro\nutf2 "Mmus\Nutf2-ps2, Mmus\Nutf2" Hsap\NUTF2 " adult stage | male , adult stage | female " testis

"lethal,female,lethal - all die before end of larval stage,some die during larval stage,female fertile,viable,male,male fertile,visible,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during third instar larval stage,partially lethal - majority die,some die during pupal stage,female sterile" "eye,mesothoracic tergum" FBgn0014966 gypsy\pol gypsy\polymerase http://flybase.org/reports/FBgn0014966 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "DmeGypV int, ORF2, int, gypsy\pol, pol, RTase, RT" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032723 ssp3 short spindle 3 http://flybase.org/reports/FBgn0032723 protein_coding_gene - - spindle ; GO:0005819 | colocalizes_with inferred from direct assay "CG10666, ssp3, CG18397, Ssp3" "IPR032446:S phase cyclin A-associated protein in the endoplasmic reticulum, N-terminal" CG18397 11-Aug-17 DroID_v2017_08 Drer\scaper - Cele\Y6B3B.4 Xtro\scaper Mmus\Scaper Hsap\SCAPER "viable,fertile" FBgn0067055 Q9 Q9 http://flybase.org/reports/FBgn0067055 gene - - - Q9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,viable" chaeta FBgn0036987 CG5274 - http://flybase.org/reports/FBgn0036987 protein_coding_gene - - - CG5274 IPR027844:Protein of unknown function DUF4507 CG5274 11-Aug-17 DroID_v2017_08 Drer\zgc:56409 - Cele\Y56A3A.31 Xtro\c7orf26 Mmus\E130309D02Rik Hsap\C7orf26 "viable,fertile" DRSC11774 I 1.6241633 -0.55302344 0.020185487 0.360656914 0.208308987 0.300474956 FBgn0044123 E(rst)B50 E(rst)B50 http://flybase.org/reports/FBgn0044123 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B50, E(rst)B50" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "eye,cone cell,primary pigment cell,secondary pigment cell,ectopic,tertiary pigment cell,interommatidial bristle" FBgn0028025 l(3)S103603 lethal (3) S103603 http://flybase.org/reports/FBgn0028025 gene - - - "1036/03, l(3)S103603" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0041839 E(Sev-CycE)G66 E(Sev-CycE)G66 http://flybase.org/reports/FBgn0041839 gene - - - E(Sev-CycE)G66 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267091 CR45535 - http://flybase.org/reports/FBgn0267091 non_protein_coding_gene - - - CR45535 - CR45535 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014376 ptz pitzi http://flybase.org/reports/FBgn0014376 - gene - - - ptz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260032 siren2 siren 2 http://flybase.org/reports/FBgn0260032 gene - - - siren2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0024666 l(2)k05510 lethal (2) k05510 http://flybase.org/reports/FBgn0024666 - gene - - - "55/10, l(2)k05510" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0003497 Sq Squat http://flybase.org/reports/FBgn0003497 - gene - - - Sq - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "leg,head,adult thorax" FBgn0031092 CG9577 - http://flybase.org/reports/FBgn0031092 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001753 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR001753 fatty acid beta-oxidation ; GO:0006635 | non-traceable author statement peroxisome ; GO:0005777 | inferred from sequence model lipid particle ; GO:0005811 | inferred from direct assay CG9577 "IPR001753:Crotonase superfamily, IPR014748:Crontonase, C-terminal, IPR029045:ClpP/crotonase-like domain" CG9577 11-Aug-17 DroID_v2017_08 Drer\ech1 "Scer\DCI1, Scer\ECI1" "Cele\Y25C1A.13, Cele\F58A6.1" Xtro\ech1 Mmus\Ech1 Hsap\ECH1 viable FBgn0037726 CG9492 - http://flybase.org/reports/FBgn0037726 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q8TE73 microtubule associated complex ; GO:0005875 | inferred from direct assay dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG9492, DHC3B" "IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain" CG9492 11-Aug-17 DroID_v2017_08 "Drer\dnah2, Drer\dnah1, Drer\dnah3, Drer\si:dkeyp-86b9.1, Drer\dnah9l, Drer\dnah7, Drer\dync1h1, Drer\dnah7l, Drer\si:dkeyp-87a6.1, Drer\dnah12, Drer\wu:fj30b09, Drer\dnah5" Scer\DYN1 "Cele\che-3, Cele\dhc-1" "Xtro\dnah14, Xtro\dnah5, Xtro\dnah2, Xtro\dnah7" "Mmus\Dnah1, Mmus\Dnah5, Mmus\Dnah8, Mmus\Dnah11, Mmus\Dnah7b, Mmus\Dnah7a, Mmus\Dnah17, Mmus\Dnah6, Mmus\Dnah10, Mmus\Dnah9, Mmus\Dync2h1, Mmus\Dnhd1, Mmus\Dync1h1, Mmus\Dnah12, Mmus\Dnah3, Mmus\Dnah2" "Hsap\DNAH17, Hsap\DNAH9, Hsap\DNAH7, Hsap\CCDC88B, Hsap\DNHD1, Hsap\DNAH6, Hsap\DYNC2H1, Hsap\DNAH8, Hsap\DNAH12, Hsap\DNAH14, Hsap\DNAH3, Hsap\DNAH1, Hsap\DNAH10, Hsap\DNAH2, Hsap\DYNC1H1, Hsap\DNAH11, Hsap\DNAH5" "auditory perception defective,neurophysiology defective" FBgn0262563 CG43103 - http://flybase.org/reports/FBgn0262563 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43103, Dm_2R:55417" - CG43103 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044101 E(rst)C532 E(rst)C532 http://flybase.org/reports/FBgn0044101 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C532, E(rst)C532" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069427 JJF014 JJF014 http://flybase.org/reports/FBgn0069427 gene - - - JJF014 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0029539 CG11663 - http://flybase.org/reports/FBgn0029539 protein_coding_gene - - - "BcDNA:AT05678, CG11663" IPR015943:WD40/YVTN repeat-like-containing domain CG11663 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010179 tu(2)49k tu(2)49k http://flybase.org/reports/FBgn0010179 - gene - - - tu(2)49k - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,melanotic mass phenotype" melanotic mass FBgn0039675 ppk21 pickpocket 21 http://flybase.org/reports/FBgn0039675 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK21, CG12048, ppk21, Ppk21" IPR001873:Epithelial sodium channel CG12048 11-Aug-17 DroID_v2017_08 "Drer\asic1a, Drer\asic4b, Drer\asic1c, Drer\asic1b, Drer\asic2, Drer\asic4a" - "Cele\mec-10, Cele\del-10, Cele\egas-3, Cele\delm-2, Cele\unc-105, Cele\del-1, Cele\delm-1, Cele\asic-1, Cele\del-7, Cele\mec-4, Cele\egas-1, Cele\flr-1, Cele\deg-1, Cele\acd-4, Cele\degt-1, Cele\egas-2, Cele\unc-8, Cele\egas-4, Cele\acd-1, Cele\asic-2, Cele\del-4" "Xtro\asic5, Xtro\scnn1b, Xtro\scnn1d, Xtro\asic4, Xtro\scnn1a, Xtro\scnn1g, Xtro\asic1" "Mmus\Asic5, Mmus\Asic3, Mmus\Asic4, Mmus\Scnn1a, Mmus\Scnn1g, Mmus\Asic1, Mmus\Asic2, Mmus\Scnn1b" "Hsap\SCNN1G, Hsap\SCNN1B, Hsap\ASIC3, Hsap\ASIC1, Hsap\ASIC5, Hsap\SCNN1D, Hsap\ASIC2, Hsap\SCNN1A, Hsap\ASIC4" viable FBgn0037935 CG6834 - http://flybase.org/reports/FBgn0037935 protein_coding_gene myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A - - CG6834 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG6834 11-Aug-17 DroID_v2017_08 - - "Cele\H06H21.8, Cele\nhr-246, Cele\F20D6.5" - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0002234 l(3)68Ba lethal (3) 68Ba http://flybase.org/reports/FBgn0002234 FBgn0002230 gene - - - "l(3)C141, A, l(3)A, l(3)68Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266493 s-108 - http://flybase.org/reports/FBgn0266493 gene - - - s-108 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037044 CG10585 - http://flybase.org/reports/FBgn0037044 protein_coding_gene - isoprenoid biosynthetic process ; GO:0008299 | inferred from electronic annotation with InterPro:IPR000092 - CG10585 "IPR008949:Isoprenoid synthase domain, IPR000092:Polyprenyl synthetase" CG10585 11-Aug-17 DroID_v2017_08 "Drer\pdss2, Drer\pdss1" Scer\COQ1 - "Xtro\pdss1, Xtro\pdss2" "Mmus\Pdss2, Mmus\Pdss1" "Hsap\PDSS2, Hsap\PDSS1" "viable,fertile,lethal,partially lethal - majority die,visible" "embryonic/larval hemocyte | third instar larval stage,mesothoracic tergum" FBgn0267173 CR45613 - http://flybase.org/reports/FBgn0267173 non_protein_coding_gene - - - CR45613 - CR45613 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020594 anon-57Cc anon-57Cc http://flybase.org/reports/FBgn0020594 - gene - - - anon-57Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058402 CG40402 - http://flybase.org/reports/FBgn0058402 protein_coding_gene - - - CG40402 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010319 Cdi11 Cyclin-dependent kinase interactor 11 http://flybase.org/reports/FBgn0010319 - gene - - - "CDI11, cdi11, Cdi11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044002 Su(rst)C352 Su(rst)C352 http://flybase.org/reports/FBgn0044002 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C352, Su(rst)C352" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264407 FCG-J - http://flybase.org/reports/FBgn0264407 gene - - - "FCG-J, FC G-J" - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0015851 anon-10Cd anon-10Cd http://flybase.org/reports/FBgn0015851 - gene - - - anon-10Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065367 l(2)SH1715 lethal (2) SH1715 http://flybase.org/reports/FBgn0065367 gene - - - "l(2)SH1715, l(2)SH2 1715" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026353 Su(SuRaf1)2 Su(SuRaf1)2 http://flybase.org/reports/FBgn0026353 - gene - - - "Su[Su(Raf)1]2, Su(SuRaf1)2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029522 CG13373 - http://flybase.org/reports/FBgn0029522 protein_coding_gene - - - CG13373 IPR022773:Siva CG13373 11-Aug-17 DroID_v2017_08 Drer\siva1 - - Xtro\siva1 Mmus\Siva1 Hsap\SIVA1 "viable,fertile" FBgn0001007 fs(3)6m45 female sterile (3) 6m45 http://flybase.org/reports/FBgn0001007 - gene - - - fs(3)6m45 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "oocyte,ovary" FBgn0033753 Cyp301a1 Cyp301a1 http://flybase.org/reports/FBgn0033753 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 tergite morphogenesis ; GO:0007490 | inferred from mutant phenotype" - "301a1, CG8587, Cyp301a1, Cyp301A1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG8587 11-Aug-17 DroID_v2017_08 "Drer\cyp27a1.2, Drer\zgc:136333, Drer\cyp11a2, Drer\cyp27a1.4, Drer\cyp11c1, Drer\cyp27a7, Drer\cyp27b1, Drer\si:dkey-91i10.3, Drer\si:ch211-113j14.1, Drer\cyp24a1, Drer\cyp27c1" Scer\DIT2 "Cele\cyp-37B1, Cele\cyp-44A1" "Xtro\cyp27b1, Xtro\LOC100145331, Xtro\cyp27c1, Xtro\cyp11a1, Xtro\cyp24a1, Xtro\cyp27a1" "Mmus\Cyp24a1, Mmus\Cyp27a1, Mmus\Cyp11b1, Mmus\Cyp27b1, Mmus\Cyp11a1, Mmus\Cyp11b2" "Hsap\CYP24A1, Hsap\CYP27C1, Hsap\CYP11B1, Hsap\CYP11A1, Hsap\CYP27A1, Hsap\CYP11B2, Hsap\CYP27B1" "viable,fertile,visible,recessive,partially lethal - majority live,body color defective" "tergite,adult cuticle,mesothoracic tergum" FBgn0005687 pom pomegranate http://flybase.org/reports/FBgn0005687 - gene molecular_function ; GO:0003674 | no biological data available compound eye development ; GO:0048749 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available pom - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "eye,ommatidium" FBgn0043571 SK2-3 SK2-3 http://flybase.org/reports/FBgn0043571 gene - - - SK2-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267074 CR45518 - http://flybase.org/reports/FBgn0267074 non_protein_coding_gene - - - CR45518 - CR45518 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038373 CG4546 - http://flybase.org/reports/FBgn0038373 protein_coding_gene "kinase activity ; GO:0016301 | inferred from electronic annotation with InterPro:IPR022413, InterPro:IPR022414, InterPro:IPR022415" multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG4546 "IPR000749:ATP:guanido phosphotransferase, IPR014746:Glutamine synthetase/guanido kinase, catalytic domain, IPR022413:ATP:guanido phosphotransferase, N-terminal, IPR022414:ATP:guanido phosphotransferase, catalytic domain, IPR022415:ATP:guanido phosphotransferase active site" CG4546 11-Aug-17 DroID_v2017_08 "Drer\ckmb, Drer\ckba, Drer\ckmt1, Drer\ckmt2b, Drer\ckmt2a, Drer\ckma, Drer\ckbb" - "Cele\ZC434.8, Cele\F32B5.1, Cele\W10C8.5, Cele\argk-1, Cele\F46H5.3, Cele\F11G11.13" "Xtro\ckm, Xtro\ckmt1b, Xtro\ckb" "Mmus\Ckm, Mmus\Ckmt2, Mmus\Mycbp, Mmus\Ckb, Mmus\Ckmt1" "Hsap\MYCBP, Hsap\CKM, Hsap\CKMT1A, Hsap\CKMT2, Hsap\CKMT1B, Hsap\CKB" viable FBgn0013454 fs(2)neo11 fs(2)neo11 http://flybase.org/reports/FBgn0013454 - gene - - - fs(2)neo11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,fertile" FBgn0082189 l(3)S012606 lethal (3) S012606 http://flybase.org/reports/FBgn0082189 gene - - - l(3)S012606 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264881 CG44072 - http://flybase.org/reports/FBgn0264881 protein_coding_gene - - - CG44072 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266850 CR45311 - http://flybase.org/reports/FBgn0266850 non_protein_coding_gene - - - CR45311 - CR45311 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031646 CG2837 - http://flybase.org/reports/FBgn0031646 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2837 - CG2837 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0063408 l(3)3450-O lethal (3) 3450-O http://flybase.org/reports/FBgn0063408 gene - - - l(3)3450-O - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0028468 rtet tetracycline resistance http://flybase.org/reports/FBgn0028468 protein_coding_gene tetracycline transporter activity ; GO:0008493 | inferred from biological aspect of ancestor with PANTHER:PTN001921260 tetracycline transport ; GO:0015904 | inferred from biological aspect of ancestor with PANTHER:PTN001921260 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 oogenesis ; GO:0048477 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701 brush border membrane ; GO:0031526 | inferred from biological aspect of ancestor with PANTHER:PTN001921260" "CG5760, Drtet, l(3)07086, BcDNA:LD28419, anon-WO0119857.1, rtet" "IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG5760 11-Aug-17 DroID_v2017_08 Drer\mfsd10 "Scer\SGE1, Scer\YCR023C" "Cele\Y71G12B.25, Cele\F10D7.2, Cele\unc-17" Xtro\mfsd10 Mmus\Mfsd10 Hsap\MFSD10 "viable,fertile,lethal,recessive,female sterile,lethal - all die before end of larval stage,some die during larval stage" "ovariole,germline clone,egg" FBgn0267037 CR45481 - http://flybase.org/reports/FBgn0267037 non_protein_coding_gene - - - CR45481 - CR45481 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260330 GSd482 - http://flybase.org/reports/FBgn0260330 gene - - - GSd482 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0037175 CG14455 - http://flybase.org/reports/FBgn0037175 protein_coding_gene enzyme activator activity ; GO:0008047 | inferred from electronic annotation with InterPro:IPR028996 ganglioside catabolic process ; GO:0006689 | inferred from electronic annotation with InterPro:IPR028996 - CG14455 "IPR028996:Ganglioside GM2 activator, IPR010512:Protein of unknown function DUF1091" CG14455 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053127 CG33127 - http://flybase.org/reports/FBgn0053127 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG33127 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG33127 11-Aug-17 DroID_v2017_08 "Drer\prss60.2, Drer\prss60.1, Drer\try, Drer\prss60.3" - "Cele\try-3, Cele\svh-1" - "Mmus\1810009J06Rik, Mmus\2210010C04Rik, Mmus\Klk1b3" - FBgn0265597 rad radish http://flybase.org/reports/FBgn0265597 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with RapGAP1 regulation of small GTPase mediated signal transduction ; GO:0051056 | inferred from electronic annotation with InterPro:IPR000331 anesthesia-resistant memory ; GO:0007615 | inferred from direct assay olfactory learning ; GO:0008355 | traceable author statement anesthesia-resistant memory ; GO:0007615 | traceable author statement regulation of heart contraction ; GO:0008016 | inferred from mutant phenotype neuronal cell body ; GO:0043025 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG44424, rad, CG42629, CG42628, rsh, CG15720, CG4346, radish, CG4368, CG18646, Rad, FBpp0073550, R5_X:12971309..12973132" "IPR000210:BTB/POZ domain, IPR000331:Rap GTPase activating protein domain, IPR011333:SKP1/BTB/POZ domain, IPR001781:Zinc finger, LIM-type" CG44424 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-182d3.1, Drer\zmp:0000001168, Drer\si:dkey-166d12.2, Drer\sipa1l3, Drer\sipa1l2, Drer\rap1gap2a, Drer\sipa1l1, Drer\LOC101882292, Drer\ralgapa2" - Cele\sipa-1 "Xtro\sipa1l1, Xtro\rap1gap, Xtro\ralgapa1, Xtro\rap1gap2, Xtro\garnl3" "Mmus\Rap1gap2, Mmus\Sipa1l1, Mmus\Sipa1, Mmus\Ralgapa1, Mmus\Sipa1l3, Mmus\Ralgapa2, Mmus\Rap1gap, Mmus\Sipa1l2, Mmus\Garnl3" "Hsap\SIPA1L2, Hsap\RAP1GAP, Hsap\SIPA1L1, Hsap\SIPA1, Hsap\SIPA1L3, Hsap\RALGAPA1, Hsap\GARNL3, Hsap\RALGAPA2, Hsap\RAP1GAP2" DRSC22865 IE -1.527563262 -0.024275387 -0.767896929 -1.776137846 -0.466784737 -0.017405572 FBgn0061166 l(1)3Ar lethal (1) 3Ar http://flybase.org/reports/FBgn0061166 gene - - - l(1)3Ar - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035878 CG7182 - http://flybase.org/reports/FBgn0035878 protein_coding_gene - - - CG7182 IPR013126:Heat shock protein 70 family CG7182 11-Aug-17 DroID_v2017_08 "Drer\hsp70.1, Drer\hsp70l, Drer\hspa5, Drer\hspa14, Drer\hspa12b, Drer\si:dkey-4p15.3, Drer\hsp70.2, Drer\hspa4l, Drer\hspa12a, Drer\hsc70, Drer\hspa13, Drer\si:ch211-199o1.2, Drer\hspa8" "Scer\KAR2, Scer\SSA2, Scer\SSQ1, Scer\SSB2, Scer\SSA4, Scer\SSZ1, Scer\SSA1, Scer\SSB1, Scer\SSA3" Cele\F11F1.1 "Xtro\hspa1l, Xtro\hspa1b, Xtro\hspa14, Xtro\hspa1a, Xtro\hsp70, Xtro\hspa8, Xtro\hspa5, Xtro\hspa2, Xtro\hspa12b, Xtro\hspa13" "Mmus\Hspa1l, Mmus\Hspa12b, Mmus\Hspa13, Mmus\Hspa4l, Mmus\Hspa2, Mmus\Hspa1a, Mmus\Hspa14, Mmus\Hspa4, Mmus\Hspa12a, Mmus\Hspa5, Mmus\Hspa8" "Hsap\HSPA1B, Hsap\HSPA8, Hsap\HSPA1L, Hsap\HSPA12B, Hsap\HSPA2, Hsap\HSPA4L, Hsap\HSPA5, Hsap\HSPA13, Hsap\HSPA14, Hsap\HSPA12A, Hsap\HSPA6, Hsap\HSPA1A" viable embryonic/larval hemocyte | third instar larval stage FBgn0019885 anon-63BC-T2 anon-63BC-T2 http://flybase.org/reports/FBgn0019885 - gene - - - "T2, 63B-T2, anon-63BC-T2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038653 CG18208 - http://flybase.org/reports/FBgn0038653 protein_coding_gene heterotrimeric G-protein binding ; GO:0032795 | inferred from sequence or structural similarity with HGNC:281 G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity with HGNC:281 adrenergic receptor activity ; GO:0004935 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 cell-cell signaling ; GO:0007267 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with HGNC:281 adenylate cyclase-activating adrenergic receptor signaling pathway ; GO:0071880 | inferred from biological aspect of ancestor with PANTHER:PTN001205212 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:281 CG18208 "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG18208 11-Aug-17 DroID_v2017_08 "Drer\drd2b, Drer\htr1aa, Drer\drd2l, Drer\adra2db, Drer\htr1b, Drer\htr1d, Drer\adra2a, Drer\adra2da, Drer\LOC100330650, Drer\adra2c, Drer\drd2a, Drer\adra2b" - "Cele\ser-2, Cele\ser-4, Cele\ser-7, Cele\octr-1" "Xtro\adra2c, Xtro\adra2b, Xtro\adra2a, Xtro\htr1b" "Mmus\Htr1a, Mmus\Adra2c, Mmus\Olfr683, Mmus\Olfr919, Mmus\Adra2a, Mmus\Htr1b, Mmus\Olfr1101, Mmus\Adra2b, Mmus\Olfr275, Mmus\Drd2, Mmus\Htr1f, Mmus\Olfr684, Mmus\Olfr150, Mmus\Htr7, Mmus\Htr1d" "Hsap\HTR1F, Hsap\OR56A4, Hsap\HTR1B, Hsap\OR56A5, Hsap\HTR7, Hsap\ADRA2C, Hsap\HTR1A, Hsap\HTR1D, Hsap\DRD2, Hsap\OR5T1, Hsap\OR13F1, Hsap\ADRA2A, Hsap\OR56A1, Hsap\ADRA2B" "viable,fertile,visible" mesothoracic tergum FBgn0035648 CG13288 - http://flybase.org/reports/FBgn0035648 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from sequence model "CG13288, dmCG13288" IPR031720:Protein of unknown function DUF4728 CG13288 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266107 mei-175 meiotic 175 http://flybase.org/reports/FBgn0266107 gene - female meiotic division ; GO:0007143 | inferred from mutant phenotype - mei-175 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,meiotic cell cycle defective,female" FBgn0083999 CG41432 - http://flybase.org/reports/FBgn0083999 protein_coding_gene - - - CG41432 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267245 CR45685 - http://flybase.org/reports/FBgn0267245 non_protein_coding_gene - - - CR45685 - CR45685 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052068 Adi1 Acireductone dioxygenase 1 http://flybase.org/reports/FBgn0052068 protein_coding_gene acireductone dioxygenase [iron(II)-requiring] activity ; GO:0010309 | inferred from electronic annotation with InterPro:IPR004313 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR004313 L-methionine biosynthetic process from methylthioadenosine ; GO:0019509 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 methionine biosynthetic process ; GO:0009086 | inferred from mutant phenotype methionine metabolic process ; GO:0006555 | inferred from mutant phenotype positive regulation of reproductive process ; GO:2000243 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 "CG8000, CG32068, Adi1, Dadi1, adi1" "IPR004313:Acireductone dioxygenase ARD family, IPR011051:RmlC-like cupin domain, IPR014710:RmlC-like jelly roll fold, IPR027496:1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes" CG32068 11-Aug-17 DroID_v2017_08 "Drer\adi1, Drer\LOC554736" Scer\ADI1 "Cele\T01D1.4, Cele\F42F12.4, Cele\K07E1.1" Xtro\adi1 Mmus\Adi1 Hsap\ADI1 FBgn0031103 CG12679 - http://flybase.org/reports/FBgn0031103 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12679 IPR032007:Protein of unknown function DUF4791 CG12679 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263464 snoRNA:hts-a - http://flybase.org/reports/FBgn0263464 snoRNA_gene - - - "snoRNA:hts-a, snoHACA_05" - CR43579 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020757 Cyp6a9-rAF4-2 Cytochrome P450-6a9 related AF4-2 http://flybase.org/reports/FBgn0020757 - gene - - - "P450, AF4-2, P-450, Cyp6a9-rAF4-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267448 CR45798 - http://flybase.org/reports/FBgn0267448 non_protein_coding_gene - - - "CR45798, noncoding_18124" - CR45798 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083950 CG34114 - http://flybase.org/reports/FBgn0083950 protein_coding_gene - - - "CG14698, CG4695, CG34114, 34114" "IPR007110:Immunoglobulin-like domain, IPR003598:Immunoglobulin subtype 2, IPR013162:CD80-like, immunoglobulin C2-set, IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype" CG34114 11-Aug-17 DroID_v2017_08 "Drer\hmcn2, Drer\nphs1" - - Xtro\nphs1 Mmus\Nphs1 "Hsap\MERTK, Hsap\NPHS1, Hsap\PSG1" viable FBgn0027129 l(3)E3 lethal (3) E3 http://flybase.org/reports/FBgn0027129 - gene - - - l(3)E3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019912 Ypf1a Yolk protein factor 1a http://flybase.org/reports/FBgn0019912 - gene DNA binding ; GO:0003677 | contributes_to inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from direct assay - Ku70:Ku80 complex ; GO:0043564 | inferred from direct assay "p86, YPF1alpha, YPF1, Ypf1a" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043054 Ivk\gag Ivk element gag http://flybase.org/reports/FBgn0043054 transposable_element_gene - - - "You\gag, Ivk\gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014955 ealk easterlike http://flybase.org/reports/FBgn0014955 - gene - - - "elk, ealk" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065588 l(2)SH0908 lethal (2) SH0908 http://flybase.org/reports/FBgn0065588 gene - - - "l(2)SH0908, l(2)SH2 0908" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052303 tRNA:Cys-GCA-3-1 transfer RNA:Cysteine-GCA 3-1 http://flybase.org/reports/FBgn0052303 tRNA_gene UGC codon-amino acid adaptor activity ; GO:0033414 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033414 cytosol ; GO:0005829 | inferred by curator from GO:0033414 "AE002584.trna13-CysGCA, tRNA:C:GCA:AE002584-b, CR32303, chr3L.trna13-CysGCA, tRNA:Cys-GCA-3-1, tRNA:CR32303, tRNA-Cys-GCA-3-1, UGC" - CR32303 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070006 BG01515 BG01515 http://flybase.org/reports/FBgn0070006 gene - - - BG01515 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0085199 CG34170 - http://flybase.org/reports/FBgn0085199 protein_coding_gene - - - CG34170 - CG34170 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004962 l(1)17Ca lethal (1) 17Ca http://flybase.org/reports/FBgn0004962 - gene - - - "T13, l(1)17Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0035569 CG15876 - http://flybase.org/reports/FBgn0035569 protein_coding_gene - regulation of localization ; GO:0032879 | inferred from sequence or structural similarity with halo - "HL3, CG15876" IPR007970:Protein of unknown function DUF733 CG15876 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005748 l(1)TK243 lethal (1) TK243 http://flybase.org/reports/FBgn0005748 - gene - - - "l243, l(1)TK243" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "lamina,eye" FBgn0010024 E(Dl)D72 Enhancer of Delta D72 http://flybase.org/reports/FBgn0010024 - gene - - - E(Dl)D72 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003176 Plexate Plexate http://flybase.org/reports/FBgn0003176 - gene - - - "Px, Plexate" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026533 Dek Dek http://flybase.org/reports/FBgn0026533 "FBgn0010567, FBgn0021980, FBgn0025829, FBgn0046410, FBgn0046411, FBgn0046412" protein_coding_gene histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 regulation of double-strand break repair ; GO:2000779 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 chromatin remodeling ; GO:0006338 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 nucleoplasm ; GO:0005654 | inferred from direct assay "DEK, CG593, CG5935, l(2)04154, l(2)k09907, dDEK, EG:EG0003.6, anon-WO0172774.194, anon-WO0172774.192, anon-WO0172774.191, Dek, dek, lincRNA.S2954" "IPR003034:SAP domain, IPR014876:DEK, C-terminal" CG5935 11-Aug-17 DroID_v2017_08 Drer\dek - - Xtro\dek Mmus\Dek Hsap\DEK

"viable,lethal,recessive,fertile,male limited,long lived,temperature response defective,female limited,gravitaxis defective" DRSC07418 IE -1.933559469 -1.068475533 -3.017916871 -4.1066307 1.11703303 0.118157197 FBgn0039478 Nep5 Neprilysin 5 http://flybase.org/reports/FBgn0039478 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497 metallopeptidase activity ; GO:0008237 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497 proteolysis ; GO:0006508 | inferred from sequence model" integral component of membrane ; GO:0016021 | inferred from sequence model "CG6265, Nep5, DmeNEP5, NEP5, nep5" "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR030082:Neprilysin-21, IPR024079:Metallopeptidase, catalytic domain, IPR018497:Peptidase M13, C-terminal domain" CG6265 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\phex, Drer\mmel1, Drer\ece2b" - "Cele\nep-22, Cele\nep-4, Cele\nep-15, Cele\nep-19, Cele\nep-2, Cele\nep-25" "Xtro\ece2, Xtro\mmel1, Xtro\ecel1, Xtro\ece1" "Mmus\Ece2, Mmus\Mme, Mmus\Kel, Mmus\Mmel1, Mmus\Ecel1, Mmus\Phex, Mmus\Ece1" "Hsap\ECEL1, Hsap\MMEL1, Hsap\KEL, Hsap\PHEX, Hsap\ECE1, Hsap\ECE2, Hsap\MME" viable FBgn0028626 l(2)01034 lethal (2) 01034 http://flybase.org/reports/FBgn0028626 gene - - - l(2)01034 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028283 l(1)G0414 lethal (1) G0414 http://flybase.org/reports/FBgn0028283 gene - - - l(1)G0414 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262698 Su(VGlut)B51 - http://flybase.org/reports/FBgn0262698 gene - - - "Su(VGlut)B51, B51" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031606 CG15439 - http://flybase.org/reports/FBgn0031606 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965" lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG15439 "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR034732:Extended PHD (ePHD) domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15439 11-Aug-17 DroID_v2017_08 Drer\phf14 Scer\SNT2 Cele\phf-14 Xtro\phf14 Mmus\Phf14 Hsap\PHF14 "viable,fertile,partially lethal - majority die,visible" "chaeta,supernumerary,mesothoracic tergum" DRSC00453 K 0.131049222 -0.288534242 0.246335475 -0.938027636 -0.246309738 1.757252071 FBgn0016967 w::Dmau\w w::Dmau\w http://flybase.org/reports/FBgn0016967 - engineered_fusion_gene - - - w::Dmau\w - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,visible" pigment cell FBgn0032416 Gr33a Gustatory receptor 33a http://flybase.org/reports/FBgn0032416 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | inferred from mutant phenotype sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male mating behavior ; GO:0060179 | inferred from mutant phenotype sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from direct assay cell body ; GO:0044297 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from direct assay "CG17213, Gr33C1, Gr33a, GR33a" IPR013604:7TM chemoreceptor CG17213 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - "courtship behavior defective,male,neurophysiology defective,taste perception defective,chemosensitive behavior defective,viable" labellar taste bristle FBgn0263337 CR43418 - http://flybase.org/reports/FBgn0263337 non_protein_coding_gene - - - CR43418 - CR43418 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013251 E(var)3-5 E(var)3-5 http://flybase.org/reports/FBgn0013251 - gene - - - "E-var(3)5, E(var)3-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,enhancer of variegation" FBgn0030624 CG9106 - http://flybase.org/reports/FBgn0030624 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9106 - CG9106 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060545 l(3)S098911b lethal (3) S098911b http://flybase.org/reports/FBgn0060545 gene - - - "0989/11, l(3)S098911b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0036807 CG6893 - http://flybase.org/reports/FBgn0036807 protein_coding_gene sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 oxaloacetate transmembrane transporter activity ; GO:0015131 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 succinate transmembrane transporter activity ; GO:0015141 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 phosphate transmembrane transporter activity ; GO:1901677 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transmembrane transporter activity ; GO:0015117 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transporter activity ; GO:0015140 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 phosphate ion transmembrane transport ; GO:0035435 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 sulfate transport ; GO:0008272 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 oxaloacetate transport ; GO:0015729 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transport ; GO:0015709 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 succinate transmembrane transport ; GO:0071422 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transport ; GO:0071423 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 CG6893 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG6893 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-100f3.2, Drer\slc25a10, Drer\slc25a11" Scer\DIC1 Cele\slc-25A10 "Xtro\rangrf, Xtro\slc25a10" "Mmus\Slc25a11, Mmus\Slc25a10" "Hsap\SLC25A10, Hsap\SLC25A11" viable FBgn0036784 CG5103 - http://flybase.org/reports/FBgn0036784 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR009014 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR009014 - CG5103 "IPR005474:Transketolase, N-terminal, IPR005475:Transketolase-like, pyrimidine-binding domain, IPR009014:Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II, IPR020826:Transketolase binding site, IPR029061:Thiamin diphosphate-binding fold, IPR033248:Transketolase, C-terminal domain" CG5103 11-Aug-17 DroID_v2017_08 "Drer\tktb, Drer\tkta" "Scer\TKL2, Scer\TKL1" Cele\tkt-1 "Xtro\tkt, Xtro\tktl2" "Mmus\Tktl2, Mmus\Tktl1, Mmus\Tkt" "Hsap\TKTL1, Hsap\TKT, Hsap\TKTL2" viable FBgn0052284 CG32284 - http://flybase.org/reports/FBgn0052284 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "BcDNA:LP03531, CG32284" IPR002557:Chitin binding domain CG32284 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029716 CG3546 - http://flybase.org/reports/FBgn0029716 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3546 - CG3546 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264604 CR43953 - http://flybase.org/reports/FBgn0264604 non_protein_coding_gene - - - "CR43953, lincRNA.471" - CR43953 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022760 Wmc2 Wee-Mik-Complementing 2 http://flybase.org/reports/FBgn0022760 - gene - - - "WMC2, Wmc2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032994 CG17482 - http://flybase.org/reports/FBgn0032994 protein_coding_gene - - - CG17482 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001905 l(2)24Dc lethal (2) 24Dc http://flybase.org/reports/FBgn0001905 - gene - - - "jf1, l(2)jf1, l(2)24Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264359 CR43811 - http://flybase.org/reports/FBgn0264359 non_protein_coding_gene - - - "CR43811, lincRNA.S2724, lincRNA.305" - CR43811 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050489 Cyp12d1-p Cyp12d1-p http://flybase.org/reports/FBgn0050489 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 response to insecticide ; GO:0017085 | inferred from mutant phenotype response to DDT ; GO:0046680 | inferred from mutant phenotype" - "Cyp12d1, 12d1, CYP12D1, 12D1, CG18240, CG30489, Cyp12d1-p, Cyp 12d1, CYP12d1-p" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG30489 11-Aug-17 DroID_v2017_08 "Drer\cyp27a7, Drer\cyp11a2, Drer\cyp27a1.2, Drer\zgc:136333, Drer\si:ch211-113j14.1, Drer\cyp11c1, Drer\si:dkey-91i10.3, Drer\cyp27c1, Drer\cyp27a1.4, Drer\cyp27b1, Drer\cyp24a1" Scer\DIT2 "Cele\cyp-37B1, Cele\ZK177.4, Cele\cyp-44A1" "Xtro\cyp11a1, Xtro\cyp27b1, Xtro\cyp24a1, Xtro\LOC100145331, Xtro\cyp27c1, Xtro\cyp27a1" "Mmus\Cyp11b1, Mmus\Cyp11b2, Mmus\Cyp24a1, Mmus\Cyp11a1, Mmus\Cyp27b1, Mmus\Cyp27a1" "Hsap\CYP27A1, Hsap\CYP11B2, Hsap\CYP11A1, Hsap\CYP27C1, Hsap\CYP24A1, Hsap\CYP11B1, Hsap\CYP27B1" chemical resistant FBgn0260245 GSd453 - http://flybase.org/reports/FBgn0260245 gene - - - GSd453 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0067780 bsl boussole http://flybase.org/reports/FBgn0067780 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bsl - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036350 CG14111 - http://flybase.org/reports/FBgn0036350 protein_coding_gene - - - CG14111 - CG14111 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060753 l(3)S064318 lethal (3) S064318 http://flybase.org/reports/FBgn0060753 gene - - - "0643/18, l(3)S064318" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0001596 l(1)carot14 lethal (1) carot14 http://flybase.org/reports/FBgn0001596 - gene - - - "l(1)TW5, l(1)carot14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,female sterile" "wing,adult abdomen" FBgn0030613 Rab3-GEF Rab3 GDP-GTP exchange factor http://flybase.org/reports/FBgn0030613 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000988808 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 regulation of extrinsic apoptotic signaling pathway via death domain receptors ; GO:1902041 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 activation of MAPK activity ; GO:0000187 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype regulation of Rab protein signal transduction ; GO:0032483 | inferred from sequence or structural similarity with HGNC:6766 neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement regulation of cell cycle ; GO:0051726 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 neuromuscular junction of somatic muscle ; GO:0098527 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 neuronal cell body ; GO:0043025 | inferred from direct assay synaptic vesicle ; GO:0008021 | non-traceable author statement terminal bouton ; GO:0043195 | inferred from direct assay "CG5627, BEST:GH21304, anon-EST:Posey246, rab3-GEF, Rab3-GEF" "IPR001194:DENN domain, IPR005112:dDENN domain, IPR005113:uDENN domain" CG5627 11-Aug-17 DroID_v2017_08 Drer\madd - "Cele\aex-3, Cele\mtm-5" Xtro\madd Mmus\Madd Hsap\MADD "viable,fertile" FBgn0034010 CG8157 - http://flybase.org/reports/FBgn0034010 protein_coding_gene - - - "BcDNA:RE07473, CG8157" - CG8157 11-Aug-17 DroID_v2017_08 - - Cele\fipr-21 - - - viable FBgn0264909 CR44100 - http://flybase.org/reports/FBgn0264909 non_protein_coding_gene - - - CR44100 - CR44100 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004359 T48 Transcript 48 http://flybase.org/reports/FBgn0004359 - protein_coding_gene - ventral furrow formation ; GO:0007370 | inferred from mutant phenotype inferred from genetic interaction with cta apical plasma membrane ; GO:0016324 | inferred from direct assay "48, t48, anon-97D, Ubx-t48, CG5507, T48" IPR009030:Growth factor receptor cysteine-rich domain CG5507 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" ventral furrow FBgn0031695 Cyp4ac3 Cyp4ac3 http://flybase.org/reports/FBgn0031695 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CG14031, 4ac3, Cyp4ac3" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG14031 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp26c1, Drer\LOC100329425, Drer\cyp4f3, Drer\cyp19a1a, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp46a1.1, Drer\cyp46a1.3, Drer\cyp26b1, Drer\cyp19a1b, Drer\cyp46a1.2, Drer\cyp3c4, Drer\cyp3c3, Drer\cyp26a1, Drer\cyp3c1, Drer\cyp46a1.4, Drer\cyp3c2, Drer\cyp20a1, Drer\cyp4t8" "Scer\ERG5, Scer\DIT2" "Cele\cyp-37B1, Cele\cyp-29A4, Cele\cyp-13A10, Cele\cyp-13A7, Cele\cyp-13A11, Cele\cyp-13A5, Cele\cyp-25A1, Cele\cyp-13A8, Cele\cyp-29A2, Cele\cyp-25A2, Cele\cyp-32A1, Cele\cyp-42A1, Cele\cyp-31A3, Cele\cyp-13A1, Cele\cyp-25A4, Cele\cyp-14A1, Cele\cyp-37A1, Cele\cyp-31A5, Cele\cyp-13A3, Cele\cyp-25A3, Cele\cyp-13A12, Cele\cyp-31A2, Cele\cyp-29A3, Cele\cyp-32B1, Cele\cyp-13A4" "Xtro\cyp26a1, Xtro\cyp4f2, Xtro\cyp20a1, Xtro\cyp4v2, Xtro\cyp26b1, Xtro\LOC100487918, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\mgc108213, Xtro\cyp19a1, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\cyp4b1" "Mmus\Cyp4f14, Mmus\Cyp3a57, Mmus\Cyp4a29, Mmus\Cyp20a1, Mmus\Cyp4a30b, Mmus\Cyp19a1, Mmus\Cyp3a59, Mmus\Cyp3a41a, Mmus\Cyp4f18, Mmus\Cyp26b1, Mmus\Cyp3a25, Mmus\Cyp46a1, Mmus\Cyp4a32, Mmus\Cyp26c1, Mmus\Cyp4v3, Mmus\Cyp4f40, Mmus\Cyp4f39, Mmus\Cyp4a14, Mmus\Cyp4b1, Mmus\Cyp4a12a, Mmus\Cyp4x1, Mmus\Cyp4f13, Mmus\Cyp3a41b, Mmus\Cyp3a16, Mmus\Cyp4a31, Mmus\Cyp3a13, Mmus\Cyp4f37, Mmus\Cyp3a44, Mmus\Cyp4f15, Mmus\Cyp26a1, Mmus\Cyp4a12b, Mmus\Cyp4f17, Mmus\Cyp3a11, Mmus\Cyp4f16, Mmus\Cyp4a10" "Hsap\CYP4F2, Hsap\CYP3A43, Hsap\CYP4F12, Hsap\CYP4F22, Hsap\CYP26B1, Hsap\CYP4Z1, Hsap\CYP19A1, Hsap\CYP4A22, Hsap\CYP46A1, Hsap\CYP20A1, Hsap\CYP26C1, Hsap\CYP4F11, Hsap\CYP3A4, Hsap\CYP4B1, Hsap\CYP3A7, Hsap\CYP3A5, Hsap\CYP4X1, Hsap\CYP26A1, Hsap\CYP4A11, Hsap\CYP4V2, Hsap\CYP4F8, Hsap\CYP4F3" "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0025158 ms(2)A1 ms(2)A1 http://flybase.org/reports/FBgn0025158 - gene - - - ms(2)A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0003977 vir virilizer http://flybase.org/reports/FBgn0003977 FBgn0034852 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with protein_id:AAC03114.1 inferred from sequence or structural similarity with protein_id:CAA53660.1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y091 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype primary sex determination, soma ; GO:0007539 | non-traceable author statement sex determination ; GO:0007530 | traceable author statement RNA splicing, via transesterification reactions ; GO:0000375 | inferred from mutant phenotype regulation of mRNA splicing, via spliceosome ; GO:0048024 | traceable author statement dosage compensation ; GO:0007549 | traceable author statement" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from sequence or structural similarity inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG3496, vir, Vir" "IPR026736:Protein virilizer, IPR031801:Virilizer, N-terminal" CG3496 11-Aug-17 DroID_v2017_08 Drer\si:ch211-79l20.4 - - Xtro\kiaa1429 Mmus\1110037F02Rik Hsap\KIAA1429 "lethal,recessive,wild-type,sex-determination defective,female,heat sensitive,viable,lethal - all die before end of larval stage,some die during larval stage,female sterile,maternal effect,male,male fertile,partially lethal - majority die,visible" "border follicle cell,somatic clone,adult abdomen,heat sensitive,abdominal tergite 6,abdominal tergite 7,oviprotector,female gonopod,anal plate,hypoproct,chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0262636 dati datilografo http://flybase.org/reports/FBgn0262636 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 neuron projection development ; GO:0031175 | inferred from mutant phenotype generation of neurons ; GO:0048699 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype positive regulation of female receptivity ; GO:0045925 | inferred from mutant phenotype - "CG2052, dati, CG10204, DmLin29, Lin29" IPR013087:Zinc finger C2H2-type CG2052 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-121d2.7, Drer\si: zfos-932h1.3, Drer\LOC100534979, Drer\znf1174, Drer\znf362b, Drer\znf362a" Scer\AZF1 Cele\lin-29 "Xtro\zxdc, Xtro\znf362" "Mmus\Zxdc, Mmus\Zxdb, Mmus\Zfp236, Mmus\Zfp217, Mmus\Zfp362" "Hsap\ZBTB48, Hsap\ZXDB, Hsap\ZNF362, Hsap\ZXDA, Hsap\ZXDC" FBgn0000290 Cg10AB Collagen-like 10AB http://flybase.net/reports/FBgn0000290.html gene "Cg3, DCg3" 11-Aug-17 DroID_v2017_08 FBgn0264489 CG43897 - http://flybase.org/reports/FBgn0264489 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR005822 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR005822 lateral inhibition ; GO:0046331 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR005822 "CG43897, CG33205, CG32050, CG8154, CG8163, CG14172, CG32051, CG32049, BcDNA:RH19933, BcDNA:RE55923" "IPR005822:Ribosomal protein L13, IPR006643:Zasp-like motif, IPR031847:Domain of unknown function DUF4749" CG43897 11-Aug-17 DroID_v2017_08 "Drer\pdlim1, Drer\pdlim3b, Drer\pdlim2, Drer\pdlim4, Drer\pdlim3a" - - - "Mmus\Pdlim2, Mmus\Pdlim3, Mmus\Pdlim4, Mmus\Prickle4, Mmus\Pdlim1" "Hsap\BRD4, Hsap\PDLIM1, Hsap\PRICKLE4, Hsap\PDLIM3, Hsap\PDLIM2, Hsap\PDLIM4" FBgn0265778 PDZ-GEF PDZ domain-containing guanine nucleotide exchange factor http://flybase.org/reports/FBgn0265778 protein_coding_gene Rap guanyl-nucleotide exchange factor activity ; GO:0017034 | inferred from sequence or structural similarity with HGNC:16854 Ras GTPase binding ; GO:0017016 | inferred from physical interaction with Rap1 Rap guanyl-nucleotide exchange factor activity ; GO:0017034 | inferred from direct assay "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001895, InterPro:IPR019804 oogenesis ; GO:0048477 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype MAPK cascade ; GO:0000165 | inferred from genetic interaction with Raf inferred from genetic interaction with rl inferred from genetic interaction with Dsor1 adherens junction assembly ; GO:0034333 | inferred from genetic interaction with Rap1 hemocyte migration ; GO:0035099 | inferred from mutant phenotype substrate-dependent cell migration, cell extension ; GO:0006930 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype imaginal disc-derived male genitalia development ; GO:0007485 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:16854 regulation of compound eye photoreceptor development ; GO:0045314 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype inferred from genetic interaction with Rap1, cno, zip" apicolateral plasma membrane ; GO:0016327 | inferred from direct assay adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay "EC2-8, Gef26, PDZ-GEF, dizzy, CG9491, dzy, dPDZ-GEF, PDF-GEF Dizzy, l(2)k13720, GEF, D-PDZGEF, DGEF, Dzy" "IPR029071:Ubiquitin-related domain, IPR023578:Ras guanine nucleotide exchange factor domain, IPR019804:Ras guanine-nucleotide exchange factor, conserved site, IPR014710:RmlC-like jelly roll fold, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR001478:PDZ domain, IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR000595:Cyclic nucleotide-binding domain, IPR000159:Ras-associating (RA) domain, IPR018490:Cyclic nucleotide-binding-like" CG9491 11-Aug-17 DroID_v2017_08 "Drer\rasgrf2b, Drer\si:ch211-234p18.3, Drer\rapgef1a, Drer\sos1, Drer\si:dkey-253i9.4, Drer\rapgef1b, Drer\rapgef6, Drer\rapgef2" "Scer\LTE1, Scer\CDC25" "Cele\Y34B4A.4, Cele\pxf-1, Cele\sos-1" - "Mmus\Rasgrf1, Mmus\Rapgef1, Mmus\Rapgef6, Mmus\Rasgrf2, Mmus\Rapgef2, Mmus\Sos1, Mmus\Sos2" "Hsap\RAPGEF6, Hsap\RASGRF1, Hsap\RASGRF2, Hsap\SOS2, Hsap\RAPGEF2, Hsap\SOS1, Hsap\RAPGEF1" DRSC03231 E -1.115914075 -0.531928597 -1.770098189 -0.470963788 1.111480823 -0.889726447 FBgn0267180 CR45620 - http://flybase.org/reports/FBgn0267180 non_protein_coding_gene - - - CR45620 - CR45620 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020829 l(2)SA "South Amherst, Mass" http://flybase.org/reports/FBgn0020829 - gene - - - l(2)SA - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065596 l(2)SH0889 lethal (2) SH0889 http://flybase.org/reports/FBgn0065596 gene - - - "l(2)SH0889, l(2)SH2 0889" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004763 l(3)89Cd lethal (3) 89Cd http://flybase.org/reports/FBgn0004763 - gene - - - l(3)89Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0043491 flea\polyprotein flea element polyprotein http://flybase.org/reports/FBgn0043491 transposable_element_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001969, InterPro:IPR001995" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001969, InterPro:IPR001995 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584" - "blastopia\polyprotein, flea\polyprotein" "IPR034145:RTVL-H retropepsin domain, IPR026523:Paraneoplastic antigen Ma, IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR001969:Aspartic peptidase, active site, IPR001995:Peptidase A2A, retrovirus, catalytic, IPR018061:Retropepsins, IPR012337:Ribonuclease H-like domain, IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031678 CG31918 - http://flybase.org/reports/FBgn0031678 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753" - "CG18592, anon-WO0118547.477, CG31918" "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain" CG31918 11-Aug-17 DroID_v2017_08 "Drer\ece2b, Drer\mmel1, Drer\phex, Drer\ece1" - "Cele\nep-26, Cele\nep-18, Cele\nep-7, Cele\nep-5, Cele\nep-19, Cele\nep-16, Cele\nep-10, Cele\nep-13, Cele\nep-24, Cele\nep-9, Cele\nep-21, Cele\nep-3, Cele\nep-20, Cele\nep-17, Cele\nep-23, Cele\nep-12, Cele\nep-8, Cele\nep-6" "Xtro\ece2, Xtro\ece1, Xtro\ecel1, Xtro\mmel1" "Mmus\Mmel1, Mmus\Ece2, Mmus\Ece1, Mmus\Ecel1, Mmus\Mme, Mmus\Phex, Mmus\Kel" "Hsap\MME, Hsap\KEL, Hsap\PHEX, Hsap\ECE2, Hsap\MMEL1, Hsap\ECEL1, Hsap\ECE1" viable dorsal appendage FBgn0045800 Uhg1 U snoRNA host gene 1 http://flybase.org/reports/FBgn0045800 non_protein_coding_gene - - - "Dros-UHG1, dUHG1, CG14486, CR32886, BEST:GM03135, Uhg1, dUhg1, FBgn0040741" - CR32886 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264723 CR43991 - http://flybase.org/reports/FBgn0264723 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43991, CG43991" - CR43991 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005071 fs(2)OW212 female sterile (2) OW212 http://flybase.org/reports/FBgn0005071 - gene - - - fs(2)OW212 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013259 E(var)45 E(var)45 http://flybase.org/reports/FBgn0013259 - gene - - - E(var)45 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0036325 CG10752 - http://flybase.org/reports/FBgn0036325 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.236, CG10752" "IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain" CG10752 11-Aug-17 DroID_v2017_08 Drer\klhl41a - - - - - viable FBgn0013550 l(3)100Ab lethal (3) 100Ab http://flybase.org/reports/FBgn0013550 - gene - - - l(3)100Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034458 Ir56d Ionotropic receptor 56d http://flybase.org/reports/FBgn0034458 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir56d, DmelIR56d, CG15904, IR56d" - CG15904 11-Aug-17 DroID_v2017_08 - - Cele\W02A2.5 - - "Hsap\GRIK3, Hsap\GRIK2" viable FBgn0261630 CG42713 - http://flybase.org/reports/FBgn0261630 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG42713, DMG4-MB6.chr2L.16.012" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42713 11-Aug-17 DroID_v2017_08 "Drer\pi15a, Drer\r3hdml, Drer\pi15b, Drer\glipr2, Drer\crispld2, Drer\crispld1b, Drer\wu:fb59d01, Drer\LOC100536500, Drer\glipr1b, Drer\glipr2l, Drer\crispld1a" "Scer\PRY2, Scer\PRY1, Scer\PRY3" - "Xtro\crispld2, Xtro\r3hdml, Xtro\crisp2, Xtro\glipr2, Xtro\crisp3, Xtro\crisp1, Xtro\MGC108118" "Mmus\Crisp3, Mmus\Glipr2, Mmus\Glipr1, Mmus\Crispld2, Mmus\Glipr1l2, Mmus\Crisp4, Mmus\Pi15, Mmus\Crisp1, Mmus\Clec18a, Mmus\Glipr1l1, Mmus\Crisp2, Mmus\R3hdml, Mmus\Pi16, Mmus\Crispld1" "Hsap\CLEC18A, Hsap\CLEC18B, Hsap\PI16, Hsap\R3HDML, Hsap\CLEC18C, Hsap\CRISP2, Hsap\GLIPR2, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\GLIPR1, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\PI15, Hsap\CRISPLD1" FBgn0003119 po pale ocelli http://flybase.org/reports/FBgn0003119 - gene - ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype - "do, po" - - 11-Aug-17 DroID_v2017_08 - - - - - - ocellus pigment granule FBgn0033782 sug sugarbabe http://flybase.org/reports/FBgn0033782 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q8VDL9 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:Q8VDL9 insulin-like growth factor receptor signaling pathway ; GO:0048009 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay cellular response to nutrient ; GO:0031670 | inferred from direct assay" nuclear speck ; GO:0016607 | inferred from sequence or structural similarity with UniProtKB:Q8VDL9 "CG3850, sug" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3850 11-Aug-17 DroID_v2017_08 "Drer\glis2a, Drer\glis2b, Drer\glis3, Drer\aaas, Drer\LOC100333406" "Scer\YPR015C, Scer\CMR3" "Cele\ztf-14, Cele\ref-2" "Xtro\glis2, Xtro\aaas, Xtro\glis3" "Mmus\Prdm5, Mmus\Glis1, Mmus\Glis2, Mmus\Aaas" "Hsap\AAAS, Hsap\ZKSCAN5, Hsap\GLIS2, Hsap\GLIS3, Hsap\GLIS1" "developmental rate defective,heat sensitive,lethal,male,starvation stress response defective,viable" FBgn0265718 CR44525 - http://flybase.org/reports/FBgn0265718 non_protein_coding_gene - - - "incRNA.462, CR44525, lincRNA.462" - CR44525 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039647 CG14509 - http://flybase.org/reports/FBgn0039647 protein_coding_gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - "CG14510, CG14509" - CG14509 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective,fertile" FBgn0259467 C166 - http://flybase.org/reports/FBgn0259467 gene - - - C166 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing vein" FBgn0002494 l(3)SG54 lethal (3) SG54 http://flybase.org/reports/FBgn0002494 - gene - - - l(3)SG54 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,heat sensitive,some die during embryonic stage" FBgn0002823 ms(2)38C male sterile (2) 38C http://flybase.org/reports/FBgn0002823 - gene - - - "ms, ms(2)38C" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0065637 l(2)SH0765 lethal (2) SH0765 http://flybase.org/reports/FBgn0065637 gene - - - "l(2)SH0765, l(2)SH2 0765" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014340 mof males absent on the first http://flybase.org/reports/FBgn0014340 - protein_coding_gene "chromatin binding ; GO:0003682 | inferred from direct assay mRNA binding ; GO:0003729 | traceable author statement histone acetyltransferase activity (H4-K16 specific) ; GO:0046972 | traceable author statement histone acetyltransferase activity ; GO:0004402 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with nsl1 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor ; GO:0004468 | traceable author statement histone acetyltransferase activity ; GO:0004402 | inferred from direct assay histone acetyltransferase activity (H4-K16 specific) ; GO:0046972 | inferred from mutant phenotype histone acetyltransferase activity ; GO:0004402 | inferred from sequence or structural similarity with SGD:S000000148 inferred from sequence or structural similarity with SGD:S000004734" "dosage compensation by hyperactivation of X chromosome ; GO:0009047 | non-traceable author statement histone H4-K16 acetylation ; GO:0043984 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype histone acetylation ; GO:0016573 | traceable author statement positive regulation of sequence-specific DNA binding transcription factor activity ; GO:0051091 | inferred from mutant phenotype response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype peptidyl-lysine acetylation ; GO:0018394 | traceable author statement regulation of histone H4 acetylation involved in response to DNA damage stimulus ; GO:2000873 | inferred from mutant phenotype dosage compensation ; GO:0007549 | inferred from mutant phenotype inferred from genetic interaction with msl-2 cellular response to ionizing radiation ; GO:0071479 | inferred from mutant phenotype DNA damage response, signal transduction by p53 class mediator ; GO:0030330 | inferred from mutant phenotype" "MSL complex ; GO:0072487 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay X chromosome ; GO:0000805 | traceable author statement X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | traceable author statement polytene chromosome interband ; GO:0005705 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from direct assay NSL complex ; GO:0044545 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay" "MOF, CG3025, dMOF, dmMOF, Mof, max, mof" "IPR002717:Histone acetyltransferase domain, MYST-type, IPR016181:Acyl-CoA N-acyltransferase, IPR016197:Chromo domain-like, IPR025995:RNA binding activity-knot of a chromodomain" CG3025 11-Aug-17 DroID_v2017_08 "Drer\kat5a, Drer\kat6b, Drer\kat8, Drer\kat7b, Drer\kat7a, Drer\kat5b, Drer\kat6a" "Scer\ESA1, Scer\SAS3, Scer\SAS2" "Cele\mys-4, Cele\mys-1, Cele\mys-2" "Xtro\kat5, Xtro\trim69.1, Xtro\xnf7, Xtro\kat7, Xtro\kat8" "Mmus\Kat5, Mmus\Kat8, Mmus\Kat6a, Mmus\Kat7, Mmus\Kat6b" "Hsap\KAT5, Hsap\KAT8, Hsap\KAT6B, Hsap\KAT6A, Hsap\KAT7" larval stage--adult stage "female fertile,non-suppressor of variegation,wild-type,lethal,male,recessive,viable,female,increased cell death,radiation sensitive,partially lethal - majority die,female sterile,short lived,male limited,large body,female limited,decreased cell growth,lethal - all die during larval stage" "heart primordium,eye disc,wing disc,embryonic/larval fat body" FBgn0259171 Pde9 Phosphodiesterase 9 http://flybase.org/reports/FBgn0259171 protein_coding_gene "3',5'-cyclic-nucleotide phosphodiesterase activity ; GO:0004114 | inferred from electronic annotation with InterPro:IPR002073 3',5'-cyclic-nucleotide phosphodiesterase activity ; GO:0004114 | inferred from sequence model" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002073 cyclic nucleotide metabolic process ; GO:0009187 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG42276, PDE9, CG32648, CG3765, CG3761, CG1627, Pde9, CG3754" "IPR002073:3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR003607:HD/PDEase domain, IPR023088:3'5'-cyclic nucleotide phosphodiesterase, IPR023174:3'5'-cyclic nucleotide phosphodiesterase, conserved site" CG42276 11-Aug-17 DroID_v2017_08 "Drer\LOC571737, Drer\pde4ba, Drer\pde11a, Drer\pde4bb, Drer\pde4a, Drer\pde5aa, Drer\pde6c, Drer\pde5ab, Drer\pde6b, Drer\pde10a, Drer\crtc1b, Drer\pde9a, Drer\pde6a, Drer\pde4ca, Drer\pde2a, Drer\pde4d, Drer\si:dkey-219c10.4, Drer\pde11al, Drer\pde9al, Drer\pde7a" Scer\PDE2 Cele\pde-6 "Xtro\pde7b, Xtro\pde6a, Xtro\pde4c, Xtro\pde2a, Xtro\pde5a, Xtro\pde7a, Xtro\pde4a, Xtro\LOC100493061, Xtro\pde6b, Xtro\pde9a, Xtro\pde10a, Xtro\pde11a, Xtro\pde4b, Xtro\pde4d, Xtro\pde6c" "Mmus\Pde10a, Mmus\Pde9a, Mmus\Pde2a, Mmus\Pde6b, Mmus\Pde8a, Mmus\Pde11a, Mmus\Pde4b, Mmus\Pde8b, Mmus\Pde4a, Mmus\Pde7b, Mmus\Pde5a, Mmus\Pde7a, Mmus\Pde6a, Mmus\Pde4d, Mmus\Pde6c, Mmus\Pde4c" "Hsap\PDE4D, Hsap\PDE10A, Hsap\PDE2A, Hsap\PDE8B, Hsap\PDE4C, Hsap\PDE7A, Hsap\PDE6B, Hsap\PDE6C, Hsap\PDE9A, Hsap\PDE4B, Hsap\PDE4A, Hsap\PDE5A, Hsap\PDE6A, Hsap\PDE11A, Hsap\PDE8A, Hsap\PDE7B" FBgn0038529 CG14323 - http://flybase.org/reports/FBgn0038529 protein_coding_gene - - - CG14323 - CG14323 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC14802 E -0.68520201 -0.081526843 1.966632417 0.21844102 -0.279816649 0.157506215 FBgn0050443 Opbp Optix-binding protein http://flybase.org/reports/FBgn0050443 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "Obp, OBP, CG12397, BcDNA:RE37461, CG30443, Opbp" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG30443 11-Aug-17 DroID_v2017_08 "Drer\LOC100001832, Drer\znf1161, Drer\znf143a, Drer\zgc:113295, Drer\zgc:113030, Drer\zgc:113377, Drer\LOC100537377, Drer\zgc:113343, Drer\LOC798256, Drer\zgc:153116, Drer\blf, Drer\LOC103908714, Drer\znf1157, Drer\si:dkey-1b17.8, Drer\LOC101885996, Drer\LOC100333228, Drer\si:rp71-1h20.5, Drer\LOC100534908, Drer\zgc:110249, Drer\si:ch73-367f21.6, Drer\si:ch211-202h22.10, Drer\LOC100535934, Drer\zgc:174288, Drer\si:ch211-155e24.3, Drer\si:ch211-161m3.4, Drer\zgc:163077, Drer\si:ch211-241e1.5, Drer\zgc:162936, Drer\zgc:113348, Drer\znf407, Drer\LOC101883936, Drer\si:dkey-226l10.6, Drer\LOC100535458, Drer\zgc:175107, Drer\klf1, Drer\zgc:171551, Drer\si:ch73-367f21.4, Drer\si:ch73-299h12.4, Drer\si:dkeyp-53d3.3, Drer\znf1178, Drer\LOC101886221, Drer\si:ch73-299h12.6, Drer\znf995, Drer\znf1154, Drer\LOC100537687, Drer\si:ch211-110e21.4, Drer\zgc:194336, Drer\LOC101884416, Drer\zgc:171220, Drer\si:dkey-210j14.3, Drer\znf971, Drer\LOC101884439, Drer\si:dkey-253d23.8, Drer\zgc:174263, Drer\si:dkeyp-68b7.7, Drer\LOC103910593, Drer\si:ch211-161m3.2, Drer\LOC100002469, Drer\znf143b, Drer\si:ch211-222k6.1, Drer\pogza, Drer\znf970, Drer\si:dkey-15h8.16, Drer\si:ch1073-127d16.1, Drer\zgc:113294, Drer\si:ch73-138e16.4" Scer\AZF1 "Cele\che-1, Cele\hinf-1, Cele\Y55F3AM.14, Cele\zfp-2, Cele\ces-1" "Xtro\znf143, Xtro\zxdc, Xtro\znf280d" "Mmus\Prdm9, Mmus\Zfp27, Mmus\Zfp280b, Mmus\Prdm4, Mmus\Zfp422, Mmus\Zfp26, Mmus\Zfp143, Mmus\Zfp808, Mmus\Zbtb24, Mmus\Pogz, Mmus\Zfp275, Mmus\Zfp280d, Mmus\Zfp280c, Mmus\Zfp523" "Hsap\ZNF808, Hsap\ZNF619, Hsap\ZNF583, Hsap\ZNF813, Hsap\POGZ, Hsap\ZNF280A, Hsap\ZNF765, Hsap\ZXDA, Hsap\ZNF280B, Hsap\ZNF280C, Hsap\ZNF418, Hsap\ZNF22, Hsap\ZNF76, Hsap\ZNF468, Hsap\ZNF280D, Hsap\ZNF17, Hsap\ZNF143, Hsap\ZXDB" "viable,fertile" FBgn0260375 GSd446 - http://flybase.org/reports/FBgn0260375 gene - - - GSd446 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0285912 mah mahogany http://flybase.org/reports/FBgn0285912 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 - "mah, CG13646" "IPR013057:Amino acid transporter, transmembrane domain" CG13646 11-Aug-17 DroID_v2017_08 "Drer\slc32a1, Drer\si:dkey-126h10.1" - "Cele\Y4C6B.2, Cele\R02F2.8, Cele\Y59H11AR.4, Cele\Y18D10A.23, Cele\F21D12.3, Cele\unc-47, Cele\Y32F6A.4" - Mmus\Slc32a1 Hsap\SLC32A1 viable FBgn0025135 su(RpII140[Z36])S12 su(RpII140[Z36])S12 http://flybase.org/reports/FBgn0025135 - gene - - - "Z36[S12], su(RpII140[Z36])S12" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082999 snoRNA:Psi28S-1192c snoRNA:Psi28S-1192c http://flybase.org/reports/FBgn0082999 snoRNA_gene - - - "snoRNA:Psi28S-1192c, Psi28S-1192c, psi28S-1192c, CR34595" - CR34595 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065639 l(2)SH0762 lethal (2) SH0762 http://flybase.org/reports/FBgn0065639 gene - - - "l(2)SH0762, l(2)SH2 0762" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0017482 T3dh Type III alcohol dehydrogenase http://flybase.org/reports/FBgn0017482 - protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001670 hydroxyacid-oxoacid transhydrogenase activity ; GO:0047988 | inferred from sequence or structural similarity with UniProtKB:Q8IWW8 alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from biological aspect of ancestor with PANTHER:PTN001691340 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001670 molecular hydrogen transport ; GO:0015993 | inferred from sequence or structural similarity with UniProtKB:Q8IWW8 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000161036 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001691340 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q8R0N6 "CG3425, T3dh" "IPR001670:Alcohol dehydrogenase, iron-type" CG3425 11-Aug-17 DroID_v2017_08 Drer\adhfe1 Scer\ADH4 Cele\Y38F1A.6 Xtro\adhfe1 Mmus\Adhfe1 Hsap\ADHFE1 "viable,fertile,visible" trichogen cell FBgn0001416 l(1)5CDa lethal (1) 5CDa http://flybase.org/reports/FBgn0001416 - gene - - - "ts155, l(1)ts155, l(1)E12, l(1)5CDa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,recessive,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,chemical sensitive" FBgn0085240 CG34211 - http://flybase.org/reports/FBgn0085240 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34211 - CG34211 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070030 BG00080 BG00080 http://flybase.org/reports/FBgn0070030 gene - - - BG00080 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,sleep defective" FBgn0085292 CG34263 - http://flybase.org/reports/FBgn0085292 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34263 IPR002350:Kazal domain CG34263 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261739 EC4330 - http://flybase.org/reports/FBgn0261739 gene - - - EC4330 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0083965 CG34129 - http://flybase.org/reports/FBgn0083965 protein_coding_gene molecular_function ; GO:0003674 | no biological data available serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG6069, SPH192, CG34129" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34129 11-Aug-17 DroID_v2017_08 "Drer\tmprss13a, Drer\tmprss13b, Drer\LOC100331291" - Cele\svh-1 - "Mmus\Try5, Mmus\1810009J06Rik, Mmus\Tmprss11d, Mmus\Prss57, Mmus\Prss40, Mmus\Gzmk, Mmus\Tmprss11c, Mmus\Prss45, Mmus\Tmprss11b, Mmus\Prss39, Mmus\Tmprss11e" "Hsap\PRSS45, Hsap\PRSS57, Hsap\GZMK, Hsap\TMPRSS11E, Hsap\PRSS3, Hsap\TMPRSS11D, Hsap\TMPRSS11B" viable FBgn0035933 CG13309 - http://flybase.org/reports/FBgn0035933 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 molecular_function ; GO:0003674 | no biological data available chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular space ; GO:0005615 | inferred from sequence model "CT32604, CG13309" IPR002557:Chitin binding domain CG13309 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020301 fs(3)100C fs(3)100C http://flybase.org/reports/FBgn0020301 - gene - - - "fs(100C), fs(3)100C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030277 CG1394 - http://flybase.org/reports/FBgn0030277 protein_coding_gene - - - "bs30g07.y1, BEST:GH24085, anon-WO0140519.177, CG1394" - CG1394 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0004825 fs(2)ltoQE45 female sterile (2) ltoQE45 http://flybase.org/reports/FBgn0004825 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoQE45 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0003710 tipE temperature-induced paralytic E http://flybase.org/reports/FBgn0003710 - protein_coding_gene voltage-gated sodium channel activity ; GO:0005248 | traceable author statement sodium channel regulator activity ; GO:0017080 | inferred from direct assay "cellular response to heat ; GO:0034605 | inferred from direct assay regulation of sodium ion transport ; GO:0002028 | inferred from direct assay sodium ion transport ; GO:0006814 | non-traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay "TipE, tip-E, CG1232, tipE" IPR031578:Na+ channel auxiliary subunit TipE CG1232 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , adult stage " " embryonic peripheral nervous system

, leg

, antenna

, antenno-maxillary complex

, adult head

, central nervous system

" "wild-type,paralytic,heat sensitive,chemical resistant,courtship behavior defective,male,recessive,neuroanatomy defective,viable,visible,lethal" "neuromuscular junction & synapse,synapse | ectopic | heat sensitive,trichogen cell" FBgn0001516 l(1)10Fj lethal (1) 10Fj http://flybase.org/reports/FBgn0001516 - gene - - - l(1)10Fj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive,cell lethal,germline clone" FBgn0040334 Tsp3A Tetraspanin 3A http://flybase.org/reports/FBgn0040334 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG10742, BACR7C10.6, EG:BACR7C10.6, Dm.Tsp3A, Tsp3A, tsp3A" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG10742 11-Aug-17 DroID_v2017_08 "Drer\tspan15, Drer\tspan5b, Drer\tspan14, Drer\zgc:110329, Drer\tspan33b, Drer\zgc:113223, Drer\tspan5a, Drer\LOC799194, Drer\tspan33a" - Cele\tsp-12 "Xtro\tspan33, Xtro\tspan15, Xtro\tspan5, Xtro\tspan17, Xtro\tspan14" "Mmus\Tspan17, Mmus\Tspan10, Mmus\Tspan5, Mmus\Tspan15, Mmus\Tspan14, Mmus\Rom1, Mmus\Tspan33" "Hsap\TSPAN14, Hsap\TSPAN33, Hsap\TSPAN15, Hsap\TSPAN17, Hsap\TSPAN10, Hsap\TSPAN5, Hsap\ROM1" "viable,fertile" "sensory mother cell,somatic clone,supernumerary" FBgn0030415 CG15726 - http://flybase.org/reports/FBgn0030415 protein_coding_gene - - - CG15726 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263329 CR43410 - http://flybase.org/reports/FBgn0263329 non_protein_coding_gene - - - CR43410 - CR43410 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260590 2L3081 - http://flybase.org/reports/FBgn0260590 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3081 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0035388 CG2162 - http://flybase.org/reports/FBgn0035388 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001374 - exon-exon junction complex ; GO:0035145 | inferred from biological aspect of ancestor with PANTHER:PTN000495129 "anon-EST:Posey170, CG2162" "IPR001374:R3H domain, IPR000504:RNA recognition motif domain" CG2162 11-Aug-17 DroID_v2017_08 "Drer\r3hcc1, Drer\r3hcc1l" - Cele\F09C8.2 - "Mmus\R3hcc1, Mmus\R3hcc1l" "Hsap\R3HCC1, Hsap\R3HCC1L" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC08557 I -0.995653385 -1.829900572 -0.127522695 -0.161080206 0.227530834 0.257245196 FBgn0003384 shakA shaking A http://flybase.org/reports/FBgn0003384 - gene - - - shakA - - 11-Aug-17 DroID_v2017_08 - - - - - - "hyperactive,courtship behavior defective,heat sensitive,jumping defective,flight defective,uncoordinated,hypoactive" FBgn0053339 CG33339 - http://flybase.org/reports/FBgn0053339 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13612, CG33339" IPR006631:Protein of unknown function DM4/12 CG33339 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086883 Pab Pale body http://flybase.org/reports/FBgn0086883 gene - - - Pab - - 11-Aug-17 DroID_v2017_08 - - - - - - "body color defective,dominant,lethal,recessive" "adult cuticle,antenna,tergite" FBgn0036747 CG6052 - http://flybase.org/reports/FBgn0036747 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469" transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 CG6052 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR026082:ABC transporter A, ABCA" CG6052 11-Aug-17 DroID_v2017_08 "Drer\abca1b, Drer\abca5, Drer\abca2, Drer\abch1, Drer\abca12, Drer\abca1a, Drer\abca3b" "Scer\SNQ2, Scer\PDR15, Scer\PDR10, Scer\CAF16, Scer\PDR5, Scer\PDR18, Scer\YOL075C, Scer\AUS1, Scer\PDR12, Scer\PDR11" "Cele\abt-4, Cele\ced-7, Cele\abt-2, Cele\abt-5" "Xtro\abca9, Xtro\abca2, Xtro\abca10, Xtro\abca3, Xtro\abca1, Xtro\abca4, Xtro\abca8" "Mmus\Abca3, Mmus\Abca13, Mmus\Abca9, Mmus\Abca8b, Mmus\Abca12, Mmus\Abca17, Mmus\Abca2, Mmus\Abca5, Mmus\Abca7, Mmus\Abca16, Mmus\Abca8a, Mmus\Abca6, Mmus\Abca14, Mmus\Abca1, Mmus\Abca4, Mmus\Abca15" "Hsap\ABCA12, Hsap\ABCA7, Hsap\ABCA2, Hsap\ABCA6, Hsap\ABCA8, Hsap\ABCA1, Hsap\ABCA13, Hsap\ABCA5, Hsap\ABCA10, Hsap\ABCA4, Hsap\ABCA3, Hsap\ABCA9" viable FBgn0013322 Pcp82 Pupal-cuticle-protein-82kD http://flybase.org/reports/FBgn0013322 - gene - - - Pcp82 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037976 Tk Tachykinin http://flybase.org/reports/FBgn0037976 protein_coding_gene tachykinin receptor binding ; GO:0071861 | inferred from physical interaction with TkR86C neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity receptor binding ; GO:0005102 | non-traceable author statement tachykinin receptor binding ; GO:0071861 | inferred from physical interaction with TkR99D adult walking behavior ; GO:0007628 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype tachykinin receptor signaling pathway ; GO:0007217 | inferred from direct assay positive regulation of sensory perception of pain ; GO:1904058 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from sequence or structural similarity response to pheromone ; GO:0019236 | inferred from mutant phenotype lipid metabolic process ; GO:0006629 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred by curator from GO:0071861 extracellular space ; GO:0005615 | inferred from direct assay "DTK1, Drm-TK-3, CG14734, Drm-TK-6, Drm-TK-5, Drm-TK-4, Drm-TK-2, Drm-TK-1, Drm-TK, Dtk, Tk, dtk, DTK, Tyk, TK-1, TK, DTK-6, DTK-3, DTK-2, DTK-5, DTK-1, DTK-4, TAP-5, DmTK6, dTK, Tachykinin 1, Tachykinin 2, Tachykinin 4, Tachykinin 5" - CG14734 11-Aug-17 DroID_v2017_08 Drer\tac1 - - Xtro\tac1 Mmus\Tac1 Hsap\TAC1 "viable,fertile,behavior defective,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,smell perception defective,locomotor behavior defective,female" FBgn0000421 displaced displaced http://flybase.org/reports/FBgn0000421 - gene - - - "dd, displaced" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female sterile" "antenna,adult head,eye" FBgn0267710 CR46043 - http://flybase.org/reports/FBgn0267710 non_protein_coding_gene - - - CR46043 - CR46043 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031058 CG14227 - http://flybase.org/reports/FBgn0031058 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | NOT non-traceable author statement" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH158, CG14227" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site" CG14227 11-Aug-17 DroID_v2017_08 - - Cele\try-3 - "Mmus\Tpsab1, Mmus\Prss28, Mmus\Prss30, Mmus\Klk8, Mmus\Prss29, Mmus\Klk14, Mmus\Tpsb2, Mmus\Klk7, Mmus\Prss33, Mmus\Klk5, Mmus\Prss48, Mmus\Klk4, Mmus\Prss32, Mmus\Prss46, Mmus\Klk10, Mmus\F12, Mmus\Tpsg1, Mmus\Prss34, Mmus\Klk12, Mmus\Prss21, Mmus\Hgfac" "Hsap\F12, Hsap\TPSAB1, Hsap\TPSD1, Hsap\HGFAC, Hsap\PRSS48, Hsap\KLK8, Hsap\KLK4, Hsap\KLK5, Hsap\TPSG1, Hsap\KLK10, Hsap\KLK14, Hsap\PRSS33, Hsap\KLK12, Hsap\TPSB2, Hsap\PRSS21, Hsap\KLK7" FBgn0039806 CG15545 - http://flybase.org/reports/FBgn0039806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15545 - CG15545 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051488 CG31488 - http://flybase.org/reports/FBgn0051488 protein_coding_gene - - - CG31488 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040806 CG13456 - http://flybase.org/reports/FBgn0040806 protein_coding_gene - - - CG13456 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265077 CR44188 - http://flybase.org/reports/FBgn0265077 non_protein_coding_gene - - - CR44188 - CR44188 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262653 l(3)ED220-1 - http://flybase.org/reports/FBgn0262653 gene - - - l(3)ED220-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during P-stage,lethal" FBgn0031985 mon2 monensin sensitivity 2 http://flybase.org/reports/FBgn0031985 protein_coding_gene cytoskeletal regulatory protein binding ; GO:0005519 | inferred from physical interaction with spir pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG31756, CG14276, CG8683, mon2, noan, Mon2" "IPR015403:Sec7, C-terminal, IPR032817:Mon2, C-terminal, IPR032691:Guanine nucleotide exchange factor, N-terminal, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR032629:Mon2, dimerisation and cyclophilin-binding domain" CG8683 11-Aug-17 DroID_v2017_08 Drer\mon2 Scer\MON2 Cele\mon-2 Xtro\mon2 Mmus\Mon2 Hsap\MON2 "viable,body color defective" mesothoracic tergum FBgn0016887 l(2)39DEl lethal (2) 39DEl http://flybase.org/reports/FBgn0016887 - gene - - - "K234, l(2)39DEl" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0061516 cri criss-cross http://flybase.org/reports/FBgn0061516 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available cri - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic epidermis,denticle belt" FBgn0032077 CG9515 - http://flybase.org/reports/FBgn0032077 protein_coding_gene nucleoside-triphosphate diphosphatase activity ; GO:0047429 | inferred from electronic annotation with InterPro:IPR003697 - - "gh06087, CG33085, BEST:GH06087, CG9515" "IPR003697:Maf-like protein, IPR029001:Inosine triphosphate pyrophosphatase-like" CG9515 11-Aug-17 DroID_v2017_08 "Drer\asmt2, Drer\asmtl, Drer\asmt" Scer\YOR111W Cele\dod-18 "Xtro\asmt, Xtro\asmtl" Mmus\Asmt "Hsap\ASMT, Hsap\ASMTL" "viable,fertile" FBgn0004963 abg ambiguous http://flybase.org/reports/FBgn0004963 - gene molecular_function ; GO:0003674 | no biological data available cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available abg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,lethal,rescuable maternal effect" "embryonic epidermis,germline clone,embryonic/first instar larval cuticle,ovary" FBgn0262024 CG42835 - http://flybase.org/reports/FBgn0262024 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42835 - CG42835 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020226 Calp14B Calpain 14B http://flybase.org/reports/FBgn0020226 - gene - - - Calp14B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031055 et eye transformer http://flybase.org/reports/FBgn0031055 protein_coding_gene cytokine receptor activity ; GO:0004896 | inferred from electronic annotation with InterPro:IPR003529 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with dome receptor activity ; GO:0004872 | inferred from sequence or structural similarity with dome defense response to bacterium ; GO:0042742 | inferred from mutant phenotype negative regulation of tyrosine phosphorylation of STAT protein ; GO:0042532 | inferred from mutant phenotype negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003529 "CG14225, et, ET, lat" "IPR003529:Long hematopoietin receptor, Gp130 family 2, conserved site, IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold" CG14225 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,stress response defective,RU486 conditional" "lamellocyte,wing,eye" FBgn0003679 te tenerchaetae http://flybase.org/reports/FBgn0003679 - gene - - - te - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,good,male,male sterile,female sterile,eye color defective" "macrochaeta,wing,wing vein,pigment cell,eye" FBgn0086061 snoRNA:Or-CD8 - http://flybase.org/reports/FBgn0086061 snoRNA_gene - - - "snoRNA:Or-CD8, orphan CD8, DmOr_cd8, CR34690" - CR34690 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250830 CG12547 - http://flybase.org/reports/FBgn0250830 protein_coding_gene - - - "CG40277, CG12547, anon-EST:Posey268" "IPR011042:Six-bladed beta-propeller, TolB-like, IPR012336:Thioredoxin-like fold, IPR013017:NHL repeat, subgroup, IPR001258:NHL repeat" CG12547 11-Aug-17 DroID_v2017_08 Drer\nhlrc2 - Cele\nhl-1 Xtro\nhlrc2 Mmus\Nhlrc2 Hsap\NHLRC2 FBgn0019921 T:nls-Sry-delta nuclear localisation signal of Sry-delta http://flybase.org/reports/FBgn0019921 - engineered_tag - - - "T:nls-Sry-delta, T:nls3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005315 mu-F mutator from Florida http://flybase.org/reports/FBgn0005315 - gene - - - mu-F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266916 Cenp-C Centromeric protein-C http://flybase.org/reports/FBgn0266916 protein_coding_gene - "protein localization to kinetochore ; GO:0034501 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype protein localization to chromosome, centromeric region ; GO:0071459 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype regulation of centromere complex assembly ; GO:0090230 | inferred from direct assay female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype regulation of centromere complex assembly ; GO:0090230 | inferred from mutant phenotype regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype kinetochore assembly ; GO:0051382 | inferred from mutant phenotype" "kinetochore ; GO:0000776 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay chromosome, centromeric region ; GO:0000775 |" "cenp-C, Cenp-C, CG31258, CenpC, CENP-C, l(3)85Aa, L1, CG11745, CG11746, CLD1, l(3)SH157, l(2)SH3 157" - CG31258 11-Aug-17 DroID_v2017_08 Drer\krtcap2 - Cele\set-2 - Mmus\Krtcap2 Hsap\KRTCAP2 DRSC14371 E -1.229021924 -0.012567605 -0.04471976 -1.960457999 -1.057280315 1.08633189 FBgn0037874 Tctp Translationally controlled tumor protein http://flybase.org/reports/FBgn0037874 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProtKB:P13693 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000241815 guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from direct assay Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | NOT inferred from direct assay microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000241815 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype double-strand break repair ; GO:0006302 | inferred from mutant phenotype positive regulation of histone phosphorylation ; GO:0033129 | inferred from direct assay positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype intra-S DNA damage checkpoint ; GO:0031573 | inferred from mutant phenotype regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay tubulin complex ; GO:0045298 | colocalizes_with inferred from sequence or structural similarity with UniProtKB:P13693 polytene chromosome ; GO:0005700 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000241815 "dTCTP, CG4800, TCTP, Tctp" "IPR018103:Translationally controlled tumour protein, conserved site, IPR018105:Translationally controlled tumour protein, IPR011057:Mss4-like, IPR034737:Translationally controlled tumor protein (TCTP) domain" CG4800 11-Aug-17 DroID_v2017_08 Drer\tpt1 Scer\TMA19 Cele\tct-1 Xtro\tpt1 Mmus\Tpt1 "Hsap\FLJ44635, Hsap\TPT1" "viable,mitotic cell cycle defective,maternal effect,lethal,recessive,small body,radiation sensitive,DNA repair defective,visible,decreased cell size,decreased cell number,lethal - all die before end of larval stage,some die during third instar larval stage,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,some die during pupal stage" "eye,wing,1st posterior cell,imaginal disc,somatic clone,trichogen cell,mesothoracic tergum" FBgn0267585 CR45923 - http://flybase.org/reports/FBgn0267585 non_protein_coding_gene - - - "CR45923, CR44101, CG17478, CG40280" - CR45923 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026250 eIF1A eukaryotic translation initiation factor 1A http://flybase.org/reports/FBgn0026250 "FBgn0025531, FBgn0025959, FBgn0038594, FBgn0062638" protein_coding_gene "translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR001253, InterPro:IPR006196, InterPro:IPR018104 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity" "translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR001253, InterPro:IPR006196, InterPro:IPR018104 translational initiation ; GO:0006413 | inferred from sequence or structural similarity phagocytosis ; GO:0006909 | inferred from mutant phenotype translation ; GO:0006412 | inferred from sequence or structural similarity smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo" nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay eukaryotic 43S preinitiation complex ; GO:0016282 | inferred from sequence or structural similarity "eIF1A, group I, Group I, CG8053, D-eIF1A, eIF-4c, D-eIF4c, anon-EST:Liang-2.3, clone 2.3, EP(3)0935, EP935, anon-EST:Posey4, eIF-1A, lincRNA.S7087" "IPR018104:Translation initiation factor 1A (eIF-1A), conserved site, IPR001253:Translation initiation factor 1A (eIF-1A), IPR006196:RNA-binding domain, S1, IF1 type, IPR012340:Nucleic acid-binding, OB-fold" CG8053 11-Aug-17 DroID_v2017_08 "Drer\eif1axb, Drer\eif1axa" Scer\TIF11 Cele\eif-1.A Xtro\eif1ax "Mmus\Eif1a, Mmus\Gm2016, Mmus\Gm2022, Mmus\Gm8300, Mmus\Gm2046, Mmus\Gm21936, Mmus\Eif1ax, Mmus\Gm5662, Mmus\Gm21319, Mmus\Gm4027, Mmus\BB287469" "Hsap\LOC107984923, Hsap\EIF1AX, Hsap\EIF1AY" "viable,fertile,lethal,recessive,cell lethalcell lethal,somatic clone" DRSC16937 I -3.735674488 -1.796659258 -0.15675353 -1.300122881 0.70594744 1.456308064 FBgn0058142 CG40142 - http://flybase.org/reports/FBgn0058142 protein_coding_gene - - - CG40142 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014277 l(2)k16904 lethal (2) k16904 http://flybase.org/reports/FBgn0014277 - gene - - - "l(2)169/4, l(2)k16904" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003622 Su(var)2-147 Suppressor of variegation 2-147 http://flybase.org/reports/FBgn0003622 - gene - - - Su(var)2-147 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262385 mir-307a mir-307a stem loop http://flybase.org/reports/FBgn0262385 miRNA_gene - - - "dme-mir-307a, miR-307, mir-307a, mir-307, CR42913, CR33611, miR-307a, dme-miR-307a" - CR42913 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing FBgn0003247 rh roughish http://flybase.org/reports/FBgn0003247 - gene - compound eye development ; GO:0048749 | inferred from mutant phenotype - rh - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "eye disc,ommatidium,eye photoreceptor cell,eye" FBgn0267385 PyK Pyruvate kinase http://flybase.org/reports/FBgn0267385 protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 potassium ion binding ; GO:0030955 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 pyruvate kinase activity ; GO:0004743 | inferred from mutant phenotype" somatic muscle development ; GO:0007525 | inferred from mutant phenotype glycolytic process ; GO:0006096 | inferred from sequence or structural similarity with SGD:S000000036 response to sucrose ; GO:0009744 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with SGD:S000000036 myoblast fusion ; GO:0007520 | inferred from mutant phenotype P granule ; GO:0043186 | inferred from physical interaction with tud inferred from physical interaction with vas cytosol ; GO:0005829 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Pyk, PK, PyK, l(3)r[Q178], CG7070, PYK, l(3)rQ178, Pk" "IPR018209:Pyruvate kinase, active site, IPR015813:Pyruvate/Phosphoenolpyruvate kinase-like domain, IPR001697:Pyruvate kinase, IPR011037:Pyruvate kinase-like, insert domain, IPR015793:Pyruvate kinase, barrel, IPR015795:Pyruvate kinase, C-terminal" CG7070 11-Aug-17 DroID_v2017_08 "Drer\pklr, Drer\pkma, Drer\pkmb" "Scer\CDC19, Scer\PYK2" "Cele\pyk-2, Cele\pyk-1" "Xtro\pklr, Xtro\pkm" "Mmus\Pklr, Mmus\Pkm" "Hsap\PKM, Hsap\PKLR" FBgn0000241 bw brown http://flybase.org/reports/FBgn0000241 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 synaptic vesicle amine transmembrane transporter activity ; GO:0005430 | inferred from mutant phenotype" ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype aminergic neurotransmitter loading into synaptic vesicle ; GO:0015842 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype eye pigment precursor transport ; GO:0006856 | traceable author statement integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "bw, CG17632, Pm, Su(w[coJ]), ptm, Su(w[co2])" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR005284:Pigment precursor permease, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17632 11-Aug-17 DroID_v2017_08 "Drer\abcg8, Drer\abcg2a, Drer\abcg4b, Drer\abcg4a, Drer\abcg1, Drer\abcg2b, Drer\abcg5" "Scer\ADP1, Scer\PDR18, Scer\YOL075C, Scer\PDR10, Scer\SNQ2, Scer\PDR15, Scer\PDR5" "Cele\wht-6, Cele\abch-1, Cele\wht-2, Cele\wht-3, Cele\wht-8" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg8, Mmus\Abcg4, Mmus\Abcg2, Mmus\Abcg1, Mmus\Abcg3, Mmus\Abcg5" "Hsap\ABCG4, Hsap\ABCG8, Hsap\ABCG1, Hsap\ABCG5" "eye color defective,dominant,chemical resistant,male,auditory perception defective,visible,viable,recessive,wild-type,lethal,fertile,enhancer of variegation" "pigment cell,pigment granule,hemolymph,ocellus,wing,eye" FBgn0267244 CR45684 - http://flybase.org/reports/FBgn0267244 non_protein_coding_gene - - - CR45684 - CR45684 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052102 CG32102 - http://flybase.org/reports/FBgn0052102 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE42781, CG32102" - CG32102 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003236 reti reticent http://flybase.org/reports/FBgn0003236 - gene - - - "ret, reti" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" FBgn0001876 l(1)XN82b lethal (1) XN82b http://flybase.org/reports/FBgn0001876 - gene - - - l(1)XN82b - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045850 l(4)102Fc lethal (4) 102Fc http://flybase.org/reports/FBgn0045850 gene - - - l(4)102Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031959 spz3 spatzle 3 http://flybase.org/reports/FBgn0031959 protein_coding_gene Toll binding ; GO:0005121 | inferred from sequence or structural similarity with spz Toll signaling pathway ; GO:0008063 | inferred from sequence or structural similarity with spz extracellular region ; GO:0005576 | inferred from sequence or structural similarity with spz "CG14533, CG7104, spz3, Spz3, CT21967, CT34263" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR029034:Cystine-knot cytokine, IPR032104:Spaetzle" CG7104 11-Aug-17 DroID_v2017_08 - Scer\MRPS17 - - - Hsap\AUH "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011446 l(3)neo2 lethal (3) neo2 http://flybase.org/reports/FBgn0011446 - gene - - - l(3)neo2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062701 EP1095 EP1095 http://flybase.org/reports/FBgn0062701 gene - - - "EP(2)1095, EP1095" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262997 CR43305 - http://flybase.org/reports/FBgn0262997 non_protein_coding_gene - - - CR43305 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011610 l(1)I33e14 lethal (1) I33e14 http://flybase.org/reports/FBgn0011610 FBgn0010206 gene - - - "l(1)33e14, l(1)I33e14" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259597 B0633 - http://flybase.org/reports/FBgn0259597 gene - - - B0633 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0262883 CR43238 - http://flybase.org/reports/FBgn0262883 non_protein_coding_gene - - - "CR43238, chr3R:26,572,448-26,572,516" - CR43238 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263094 CG43362 - http://flybase.org/reports/FBgn0263094 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43362 - CG43362 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066357 l(2)23CDg lethal (2) 23CDg http://flybase.org/reports/FBgn0066357 gene - - - l(2)23CDg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035073 CG16896 - http://flybase.org/reports/FBgn0035073 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN001068643 CG16896 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR000195:Rab-GTPase-TBC domain" CG16896 11-Aug-17 DroID_v2017_08 Drer\tbc1d31 - - Xtro\tbc1d31 Mmus\Tbc1d31 Hsap\TBC1D31 viable FBgn0013657 ms(2)neo2 ms(2)neo2 http://flybase.org/reports/FBgn0013657 - gene - - - ms(2)neo2 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0260740 Grip98 - http://flybase.org/reports/FBgn0260740 protein_coding_gene - - - "Grip98, Dgrip98, GCP3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086904 Nacalpha Nascent polypeptide associated complex protein alpha subunit http://flybase.org/reports/FBgn0086904 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9U9Q7 neurogenesis ; GO:0022008 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype - "aic, alphaNAC, alpha-NAC, NAC, l(2)04329, CG8759, Nacalpha, NACalpha" "IPR002715:Nascent polypeptide-associated complex NAC domain, IPR016641:Nascent polypeptide-associated complex subunit alpha" CG8759 11-Aug-17 DroID_v2017_08 "Drer\naca, Drer\nacad" Scer\EGD2 Cele\icd-2 "Xtro\naca, Xtro\naca.2" "Mmus\Naca, Mmus\Nacad" "Hsap\NACA, Hsap\NACA2, Hsap\NACAD" FBgn0034204 CG10953 - http://flybase.org/reports/FBgn0034204 protein_coding_gene - - - "CG10953, CG10953-PA" IPR004011:GYR motif CG10953 11-Aug-17 DroID_v2017_08 - - - - Mmus\Sprr3 - "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0259238 CG42336 - http://flybase.org/reports/FBgn0259238 protein_coding_gene - - - "CG42336, CG13210, BcDNA:AT13707, CG13211" - CG42336 11-Aug-17 DroID_v2017_08 - - Cele\C48B6.10 - - - FBgn0030327 FucT6 "alpha1,6-fucosyltransferase" http://flybase.org/reports/FBgn0030327 protein_coding_gene alpha-(1->6)-fucosyltransferase activity ; GO:0046921 | inferred from direct assay glycoprotein 6-alpha-L-fucosyltransferase activity ; GO:0008424 | inferred from sequence or structural similarity with UniProtKB:Q9BYC5 protein glycosylation in Golgi ; GO:0033578 | inferred from electronic annotation with InterPro:IPR015827 protein N-linked glycosylation ; GO:0006487 | inferred from biological aspect of ancestor with PANTHER:PTN000992822 N-glycan fucosylation ; GO:0036071 | inferred from biological aspect of ancestor with PANTHER:PTN000992822 GDP-L-fucose metabolic process ; GO:0046368 | inferred from sequence or structural similarity with UniProtKB:Q9BYC5 protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from sequence or structural similarity with UniProtKB:Q9BYC5 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR015827 Golgi cisterna membrane ; GO:0032580 | inferred from electronic annotation with InterPro:IPR015827 "Fuc-TVIII, CG2448, CK00490, BEST:CK00490, FucT6, Dm alpha1,6-FucT, dalpha6Fut" "IPR001452:SH3 domain, IPR015827:Alpha-(1,6)-fucosyltransferase, eukaryotic type, IPR027350:Glycosyltransferase family 23 (GT23) domain" CG2448 11-Aug-17 DroID_v2017_08 "Drer\fut8a, Drer\fut8b" - Cele\fut-8 Xtro\fut8 Mmus\Fut8 Hsap\FUT8 "viable,fertile,immune response defective" FBgn0265694 CR44501 - http://flybase.org/reports/FBgn0265694 non_protein_coding_gene - - - "lincRNA.962, CR44501" - CR44501 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0281841 T:cic cic fragment http://flybase.org/reports/FBgn0281841 engineered_tag - - - T:cic - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004850 Su(var)204 Suppressor of variegation 204 http://flybase.org/reports/FBgn0004850 - gene - - - "Su(var)204, 204" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0011849 tRNA:Glu-TTC-1-5 transfer RNA:Glutamic acid-TTC 1-5 http://flybase.org/reports/FBgn0011849 "FBgn0003771, FBgn0011846, FBgn0050455, FBgn0060240" tRNA_gene GAA codon-amino acid adaptor activity ; GO:0033459 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033459 cytosol ; GO:0005829 | inferred by curator from GO:0033459 "CR30455, glu-tRNA-4, AE002787.trna5-GluTTC, tRNA:E4, tRNA:E:TTC:AE002787-b, tRNA:glu4:56Fb, tRNA:Glu, chr2R.trna63-GluTTC, tRNA:Glu-TTC-1-5, tRNA:E4:56Fb, tRNA-Glu-TTC-1-5, GAA" - CR30455 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033540 Elp2 Elongator complex protein 2 http://flybase.org/reports/FBgn0033540 protein_coding_gene microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 endopeptidase activator activity ; GO:0061133 | inferred from sequence or structural similarity with UniProtKB:Q16186 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from sequence or structural similarity with UniProtKB:Q16186 proteasome assembly ; GO:0043248 | inferred from sequence or structural similarity with UniProtKB:Q16186 cell cortex ; GO:0005938 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 microtubule associated complex ; GO:0005875 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 microtubule ; GO:0005874 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 kinetochore ; GO:0000776 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 proteasome complex ; GO:0000502 | inferred from sequence or structural similarity with UniProtKB:Q16186 "CG1187, CG11887, Stip, elp-2, D-elp2, Elp2, StIP" "IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG11887 11-Aug-17 DroID_v2017_08 "Drer\elp2, Drer\nwd1" Scer\ELP2 Cele\elpc-2 Xtro\elp2 Mmus\Elp2 Hsap\ELP2 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0029039 l(2)G56 lethal (2) G56 http://flybase.org/reports/FBgn0029039 gene - - - "G56, l(2)G56" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266745 CG45218 - http://flybase.org/reports/FBgn0266745 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45218 - CG45218 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261926 CG42793 - http://flybase.org/reports/FBgn0261926 protein_coding_gene - - - "CG42793, CG43203" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033043 Or42b Odorant receptor 42b http://flybase.org/reports/FBgn0033043 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from mutant phenotype odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b sensory perception of smell ; GO:0007608 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "42b, DOR118, 41E.1, CG12754, Or42b, OR42b" "IPR004117:Olfactory receptor, insect" CG12754 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,smell perception defective" FBgn0030091 CG7065 - http://flybase.org/reports/FBgn0030091 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7065 - CG7065 11-Aug-17 DroID_v2017_08 "Drer\smarca4a, Drer\smarca2" "Scer\STH1, Scer\SNF2" "Cele\C52B9.8, Cele\swsn-4" - "Mmus\Smarca4, Mmus\Smarca2" "Hsap\SMARCA4, Hsap\SMARCA2" "lethal,some die during pupal stage,viable" DRSC25280 K 0.304504596 1.188708194 1.426216408 1.069094513 1.723976147 0.825441875 FBgn0265015 S042938 - http://flybase.org/reports/FBgn0265015 gene - - - S042938 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084606 1038 1038 http://flybase.org/reports/FBgn0084606 gene - - - 1038 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026636 l(2)k15801 lethal (2) k15801 http://flybase.org/reports/FBgn0026636 - gene - - - l(2)k15801 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015217 E(var)53E Enhancer of variegation 53E http://flybase.org/reports/FBgn0015217 - gene - - - "E(var)2-53E, E(var)53E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,enhancer of variegation,dominant" FBgn0267531 CR45871 - http://flybase.org/reports/FBgn0267531 non_protein_coding_gene - - - CR45871 - CR45871 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002731 mfs(3)G male female sterile G http://flybase.org/reports/FBgn0002731 - gene - - - "fs(3)4, mfs(3)G" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male sterile,viable,poor,visible" "egg chamber,adult fat body,metathoracic tibia,metathoracic tarsal segment" FBgn0036157 CG7560 - http://flybase.org/reports/FBgn0036157 protein_coding_gene methylenetetrahydrofolate reductase (NAD(P)H) activity ; GO:0004489 | inferred from biological aspect of ancestor with PANTHER:PTN000472667 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003171 methionine metabolic process ; GO:0006555 | inferred from electronic annotation with InterPro:IPR003171 one-carbon metabolic process ; GO:0006730 | inferred from biological aspect of ancestor with PANTHER:PTN000472667 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000472667 "gh18008, BEST:GH18008, CG7560" "IPR003171:Methylenetetrahydrofolate reductase, IPR029041:FAD-linked oxidoreductase-like" CG7560 11-Aug-17 DroID_v2017_08 Drer\mthfr "Scer\MET12, Scer\MET13" Cele\mthf-1 "Xtro\mthfr, Xtro\lcor" Mmus\Mthfr Hsap\MTHFR viable FBgn0033481 CG12920 - http://flybase.org/reports/FBgn0033481 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12920 - CG12920 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264517 CR43916 - http://flybase.org/reports/FBgn0264517 non_protein_coding_gene - - - CR43916 - CR43916 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000803 fs(1)de14 female sterile (1) defective eggs 14 http://flybase.org/reports/FBgn0000803 - gene - - - "de14, fs(1)de14" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "dorsal appendage,chorion,endochorion" FBgn0264702 CR43971 - http://flybase.org/reports/FBgn0264702 non_protein_coding_gene - - - CR43971 - CR43971 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083997 CG41355 - http://flybase.org/reports/FBgn0083997 protein_coding_gene - - - CG41355 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004073 fs(2)mel7 female sterile (2) maternal effect lethal 7 http://flybase.org/reports/FBgn0004073 - gene - - - "Mel 7, fs(2)mel7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,semidominant,some die during embryonic stage" "embryonic/larval posterior spiracle,maternal effect" FBgn0016043 lup-1 loop unfolding protein-1 http://flybase.org/reports/FBgn0016043 - gene - sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype - "ms(3)HB223, lup-1, 155-34" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female semi-sterile,female sterile" "Y chromosome loop,spermatid axoneme,axonemal dynein complex,axonemal microtubule | ectopic,axonemal microtubule | supernumerary" FBgn0052946 CG32946 - http://flybase.org/reports/FBgn0052946 protein_coding_gene - - - CG32946 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085812 CR41601 - http://flybase.org/reports/FBgn0085812 non_protein_coding_gene - - - CR41601 - CR41601 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010832 l(3)04069b lethal (3) 04069b http://flybase.org/reports/FBgn0010832 - gene - - - "l(3)04069, l(3)04069b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" "crystal cell,plasmatocyte" FBgn0051014 PH4alphaSG1 prolyl-4-hydroxylase-alpha SG1 http://flybase.org/reports/FBgn0051014 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay "PHalphaSG1, CG15542, CG31014, PH4alphaSG1, SG1, Ph4alphaSG1, alphaSG1" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG31014 11-Aug-17 DroID_v2017_08 "Drer\p4ha2, Drer\p4ha1b, Drer\zgc:158254, Drer\p4ha1a, Drer\p4ha3, Drer\p4htm, Drer\zgc:152670" - "Cele\phy-3, Cele\phy-4, Cele\phy-2, Cele\C14E2.4, Cele\dpy-18, Cele\Y43F8B.19" "Xtro\p4ha3, Xtro\p4ha1, Xtro\p4ha2" "Mmus\P4ha1, Mmus\P4ha3, Mmus\P4ha2, Mmus\P4htm" "Hsap\P4HA3, Hsap\P4HA2, Hsap\P4HTM, Hsap\P4HA1" viable FBgn0010563 l(2)04008 lethal (2) 04008 http://flybase.org/reports/FBgn0010563 - gene - - - l(2)04008 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267204 CR45644 - http://flybase.org/reports/FBgn0267204 non_protein_coding_gene - - - CR45644 - CR45644 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085479 CG34450 - http://flybase.org/reports/FBgn0085479 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34450, CG32705, CG12136" - CG34450 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005107 gustF gustatory-defective F http://flybase.org/reports/FBgn0005107 - gene - - - gustF - - 11-Aug-17 DroID_v2017_08 - - - - - - taste perception defective taste bristle FBgn0265300 CR44273 - http://flybase.org/reports/FBgn0265300 non_protein_coding_gene - - - CR44273 - CR44273 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000013 abd abdominal http://flybase.org/reports/FBgn0000013 - gene - sensory organ development ; GO:0007423 | non-traceable author statement - "a-3, a(3)26, abd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semidominant" "tergite,sternite" FBgn0036427 CG4613 - http://flybase.org/reports/FBgn0036427 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP40, CG4613" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG4613 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-93a5.2, Drer\si:ch211-165b19.9, Drer\zgc:112368, Drer\tmprss3a, Drer\prss60.1, Drer\zgc:112038, Drer\prss60.3, Drer\zgc:112160, Drer\tmprss4b, Drer\si:ch211-165b19.5, Drer\gzma, Drer\zgc:153968, Drer\si:ch211-165b19.8, Drer\zgc:171592, Drer\try, Drer\LOC100004427, Drer\zgc:165423, Drer\gzm3, Drer\zgc:112302, Drer\zgc:123295, Drer\ela2l, Drer\zgc:92590, Drer\cfd, Drer\zgc:92313, Drer\LOC562139, Drer\zgc:154142, Drer\si:dkeyp-93a5.3, Drer\ctrl, Drer\prss60.2, Drer\si:dkey-16l2.17, Drer\zgc:92511, Drer\zgc:92041, Drer\zgc:163079, Drer\si:dkey-238d18.3, Drer\gzmk, Drer\ela3l, Drer\si:dkey-57c15.4, Drer\zgc:112285, Drer\zgc:92745, Drer\ela2, Drer\ctrb1, Drer\ovch1" - "Cele\try-6, Cele\try-1" "Xtro\tmprss3, Xtro\ctrb1, Xtro\prss29, Xtro\LOC100135144, Xtro\cela2a, Xtro\ctrb2, Xtro\cela3a" "Mmus\Tmprss3, Mmus\Ctrb1, Mmus\Cela3a, Mmus\Try10, Mmus\Hpn, Mmus\Try4, Mmus\Gm5771, Mmus\Ctrc, Mmus\Prss34, Mmus\Ctrl, Mmus\Cela1, Mmus\2210010C04Rik, Mmus\Klk15, Mmus\Cela3b, Mmus\Tmprss5, Mmus\Prss1, Mmus\Prss2, Mmus\Klk9, Mmus\Cela2a, Mmus\Gm10334, Mmus\Prss3, Mmus\Tmprss2" "Hsap\CTRC, Hsap\CELA3B, Hsap\CTRL, Hsap\KLK9, Hsap\HPN, Hsap\CELA1, Hsap\KLK15, Hsap\TMPRSS3, Hsap\CELA3A, Hsap\PRSS3, Hsap\TMPRSS5, Hsap\CELA2A, Hsap\CELA2B, Hsap\CTRB1, Hsap\PRSS1, Hsap\TMPRSS2, Hsap\CTRB2" viable FBgn0051213 CG31213 - http://flybase.org/reports/FBgn0051213 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 "CG4794, CG11460, CG31213" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR017871:ABC transporter, conserved site, IPR003593:AAA+ ATPase domain, IPR026082:ABC transporter A, ABCA" CG31213 11-Aug-17 DroID_v2017_08 "Drer\abch1, Drer\abca3b, Drer\abca2, Drer\abca12, Drer\abca5, Drer\abca1b, Drer\abca1a" - "Cele\abt-1, Cele\abt-4, Cele\ced-7, Cele\abt-2, Cele\abt-5" "Xtro\abca3, Xtro\abca4, Xtro\abca10, Xtro\abca1, Xtro\abca8, Xtro\abca9, Xtro\abca2" "Mmus\Abca16, Mmus\Abca8a, Mmus\Abca3, Mmus\Abca5, Mmus\Abca13, Mmus\Abca7, Mmus\Abca4, Mmus\Abca14, Mmus\Abca17, Mmus\Abca15, Mmus\Abca2, Mmus\Abca6, Mmus\Abca8b, Mmus\Abca12, Mmus\Abca9, Mmus\Abca1" "Hsap\ABCA13, Hsap\ABCA6, Hsap\ABCA5, Hsap\ABCA4, Hsap\ABCA2, Hsap\ABCA1, Hsap\ABCA7, Hsap\ABCA10, Hsap\ABCA9, Hsap\ABCA3, Hsap\ABCA12, Hsap\ABCA8" viable FBgn0265526 CR44376 - http://flybase.org/reports/FBgn0265526 non_protein_coding_gene - - - CR44376 - CR44376 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265533 CR44383 - http://flybase.org/reports/FBgn0265533 pseudogene_attribute - - - CR44383 - CR44383 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064169 l(3)64.63 lethal (3) 64.63 http://flybase.org/reports/FBgn0064169 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available l(3)64.63 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259943 Ttd8 TRPL translocation defect 8 http://flybase.org/reports/FBgn0259943 protein_coding_gene - - - Ttd8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060695 l(3)S073006 lethal (3) S073006 http://flybase.org/reports/FBgn0060695 gene - - - "0730/06, l(3)S073006" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005207 l(3)e lethal on ebony http://flybase.org/reports/FBgn0005207 - gene - - - l(3)e - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0034687 CG11475 - http://flybase.org/reports/FBgn0034687 protein_coding_gene enzyme binding ; GO:0019899 | inferred from sequence or structural similarity with HGNC:17872 regulation of response to DNA damage stimulus ; GO:2001020 | inferred from sequence or structural similarity with HGNC:17872 protein methylation ; GO:0006479 | inferred from sequence or structural similarity with HGNC:17872 cellular_component ; GO:0005575 | no biological data available CG11475 IPR002791:Domain of unknown function DUF89 CG11475 11-Aug-17 DroID_v2017_08 Drer\armt1 Scer\YMR027W Cele\F31D4.2 Xtro\armt1 Mmus\Armt1 Hsap\ARMT1 viable FBgn0038484 CG5246 - http://flybase.org/reports/FBgn0038484 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP96, BcDNA:LP06628, CG5246" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG5246 11-Aug-17 DroID_v2017_08 "Drer\LOC558805, Drer\LOC103908930, Drer\prss59.1, Drer\prss59.2, Drer\LOC560023, Drer\zmp:0000001088" - "Cele\nhl-3, Cele\svh-1, Cele\try-1" - "Mmus\Klk1b5, Mmus\Try5, Mmus\Egfbp2, Mmus\Prss1, Mmus\Klk15, Mmus\Klk1b4, Mmus\Ovch2, Mmus\2210010C04Rik, Mmus\Klk14, Mmus\Prss55, Mmus\Klk7, Mmus\Klk1b11" "Hsap\KLK14, Hsap\OVCH2, Hsap\PRSS3, Hsap\CFD, Hsap\OVCH1" viable FBgn0024294 Spn43Aa Serpin 43Aa http://flybase.org/reports/FBgn0024294 "FBgn0033144, FBgn0063809" protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG12172, Ser1, SER1, anon-WO0118057.1, Spn43Aa, Spn43 Aa, Spn43A" "IPR000215:Serpin family, IPR023796:Serpin domain" CG12172 11-Aug-17 DroID_v2017_08 "Drer\serpina1l, Drer\serpine2, Drer\serpine1, Drer\si:ch211-186e20.7, Drer\zgc:173729, Drer\serpina7, Drer\zgc:174259, Drer\serpind1, Drer\serpina10a, Drer\serpinb1l1, Drer\serpinh1b, Drer\serpinc1, Drer\serpinb1l2, Drer\serpinb1l3, Drer\serpinh1a, Drer\serpini1, Drer\serpinb1l4, Drer\serpine3, Drer\serpinb1, Drer\serpinh2, Drer\si:ch1073-416d2.3" - "Cele\srp-3, Cele\srp-6, Cele\srp-7, Cele\srp-8, Cele\srp-1, Cele\srp-2" "Xtro\serpinb11, Xtro\serpini1, Xtro\serpina3, Xtro\serpinb6, Xtro\serpine2, Xtro\serpinb5, Xtro\serpine1, Xtro\serpind1, Xtro\serpinb1, Xtro\serpina1, Xtro\serpina3k, Xtro\serpina10, Xtro\serpinb4, Xtro\serpinc1, Xtro\serpina3m, Xtro\serpini2" "Mmus\Serpinb8, Mmus\Serpinb7, Mmus\Serpina16, Mmus\Serpinb3b, Mmus\Serpinb5, Mmus\Serpina3g, Mmus\Serpina3j, Mmus\Serpine1, Mmus\Serpinb6a, Mmus\Serpina9, Mmus\Serpina1c, Mmus\Serpina3i, Mmus\Serpina3c, Mmus\Serpind1, Mmus\Serpini2, Mmus\Serpinb6d, Mmus\Serpinb9e, Mmus\Serpinb9c, Mmus\Serpinb6e, Mmus\Serpinb12, Mmus\Gm11397, Mmus\Serpina3k, Mmus\Serpinb1b, Mmus\Serpinb3c, Mmus\Serping1, Mmus\Serpina12, Mmus\Serpine2, Mmus\Serpinb3d, Mmus\Serpinh1, Mmus\Serpina3a, Mmus\Serpinb6b, Mmus\Serpine3, Mmus\Serpinb9, Mmus\Serpinb1a, Mmus\Serpinb9g, Mmus\Serpinb9f, Mmus\Serpina7, Mmus\Serpina1d, Mmus\Serpinb2, Mmus\Serpina5, Mmus\Serpina1e, Mmus\Serpinb1c, Mmus\Serpinb9d, Mmus\Serpinb13, Mmus\Serpinb10, Mmus\Serpinc1, Mmus\Serpina1a, Mmus\Serpina11, Mmus\Serpina3n, Mmus\Serpinb11, Mmus\Serpina3f, Mmus\Serpinb6c, Mmus\Serpina6, Mmus\Serpinb3a, Mmus\Serpina10, Mmus\Serpini1, Mmus\Serpinb9b" "Hsap\SERPINA10, Hsap\SERPINE3, Hsap\SERPINA5, Hsap\SERPINA9, Hsap\SERPINI1, Hsap\SERPINA12, Hsap\SERPINB10, Hsap\SERPINB7, Hsap\SERPINE1, Hsap\SERPINA11, Hsap\SERPINB12, Hsap\SERPINA3, Hsap\SERPINA7, Hsap\SERPINE2, Hsap\SERPING1, Hsap\SERPINB4, Hsap\SERPINB9, Hsap\SERPINA6, Hsap\SERPINB8, Hsap\SERPINB6, Hsap\SERPINB11, Hsap\SERPINB3, Hsap\SERPINB5, Hsap\SERPINI2, Hsap\SERPINB1, Hsap\SERPINA1, Hsap\HMSD, Hsap\SERPIND1, Hsap\SERPINA4, Hsap\SERPINH1, Hsap\SERPINB2, Hsap\SERPINC1, Hsap\SERPINB13" viable FBgn0001166 gy gouty legs http://flybase.org/reports/FBgn0001166 - gene - - - gy - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" "leg,metatarsus & metathoracic leg" FBgn0024863 l(3)05471 lethal (3) 05471 http://flybase.org/reports/FBgn0024863 - gene - - - "5471, l(3)05471" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035063 CG3594 - http://flybase.org/reports/FBgn0035063 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg3594, CG3594, Eap" IPR000504:RNA recognition motif domain CG3594 11-Aug-17 DroID_v2017_08 "Drer\ncl, Drer\rbm24b, Drer\syncripl, Drer\rbm19, Drer\syncrip, Drer\hnrnpa0a, Drer\rbm24a, Drer\hnrnpa0b" "Scer\MRD1, Scer\NOP12" "Cele\F11A10.7, Cele\sqd-1" Xtro\rbm19 "Mmus\Rbm38, Mmus\Syncrip, Mmus\Rbm24, Mmus\Hnrnpa0, Mmus\Hnrnpr, Mmus\Rbm19, Mmus\Ncl, Mmus\Rbm34" "Hsap\HNRNPR, Hsap\NCL, Hsap\RBMXL3, Hsap\RBM19, Hsap\RBM24, Hsap\SYNCRIP, Hsap\HNRNPA0, Hsap\RBM34, Hsap\RBM38, Hsap\SRSF2, Hsap\SRSF10" "viable,visible" trichogen cell FBgn0024637 l(2)k13531 lethal (2) k13531 http://flybase.org/reports/FBgn0024637 - gene - - - "135/31, l(2)k13531" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0014310 l(3)ry102 lethal (3) ry102 http://flybase.org/reports/FBgn0014310 - gene - - - l(3)ry102 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011254 ms(3)98B male sterile (3) 98B http://flybase.org/reports/FBgn0011254 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(3)06302, ms(3)98B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,male semi-sterile" FBgn0016796 exl exu-like http://flybase.org/reports/FBgn0016796 - gene - - - "Exl, exl" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263854 l(3)YD1073 - http://flybase.org/reports/FBgn0263854 gene - - - l(3)YD1073 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261840 pre-mod(mdg4)-X - http://flybase.org/reports/FBgn0261840 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-X, CG42772, RX" "IPR007588:Zinc finger, FLYWCH-type" CG42772 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033921 tej tejas http://flybase.org/reports/FBgn0033921 protein_coding_gene - piRNA biosynthetic process ; GO:1990511 | inferred from genetic interaction with tapas negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype P granule ; GO:0043186 | inferred from direct assay "anon-EST:fe1D11, Tej, CG8589, tej" "IPR025605:OST-HTH/LOTUS domain, IPR002999:Tudor domain" CG8589 11-Aug-17 DroID_v2017_08 "Drer\tdrkh, Drer\si:dkeyp-93d12.1, Drer\si:ch211-189e2.3, Drer\tdrd1, Drer\tdrd7a, Drer\tdrd6, Drer\sb:cb829, Drer\tdrd5" - "Cele\F32E10.5, Cele\eri-5, Cele\ekl-1, Cele\tag-250, Cele\rsd-6" "Xtro\tdrd5, Xtro\tdrd7" "Mmus\Tdrd1, Mmus\Tdrd12, Mmus\Tdrd6, Mmus\Tdrd7, Mmus\Tdrkh, Mmus\Tdrd5" "Hsap\TDRD5, Hsap\TDRD15, Hsap\TDRD1, Hsap\TDRD10, Hsap\TDRKH, Hsap\TDRD12, Hsap\TDRD6, Hsap\TDRD7" "female sterile,recessive,viable,female sterile germline-dependent,female semi-sterile" FBgn0262057 Spn77Ba Serpin 77Ba http://flybase.org/reports/FBgn0262057 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model negative regulation of melanization defense response ; GO:0035009 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "CG6680, Spn77Ba, spn77Ba, l(3)77ABi, Q0E8C8_DROME" "IPR000215:Serpin family, IPR023796:Serpin domain" CG6680 11-Aug-17 DroID_v2017_08 "Drer\agt, Drer\serping1, Drer\serpinf1, Drer\serpini1, Drer\serpinf2a, Drer\serpind1, Drer\serpinf2b" - "Cele\srp-8, Cele\srp-7, Cele\srp-3, Cele\srp-1, Cele\C28G1.2, Cele\srp-2, Cele\srp-6" - "Mmus\Serpind1, Mmus\Serpinb7, Mmus\Serpinf2, Mmus\Serpini2, Mmus\Serpini1, Mmus\Serpinf1, Mmus\Agt" "Hsap\SERPIND1, Hsap\SERPINF1, Hsap\AGT, Hsap\SERPINB7, Hsap\SERPINI2, Hsap\SERPINF2, Hsap\SERPINI1" FBgn0003062 Fib Fibrillarin http://flybase.org/reports/FBgn0003062 - protein_coding_gene rRNA methyltransferase activity ; GO:0008649 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 histone-glutamine methyltransferase activity ; GO:1990259 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 "tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR000692, InterPro:IPR020813 cellular response to starvation ; GO:0009267 | inferred from expression pattern rRNA methylation ; GO:0031167 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 box C/D snoRNA 3'-end processing ; GO:0000494 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 centrosome organization ; GO:0051297 | inferred from mutant phenotype histone glutamine methylation ; GO:1990258 | inferred from biological aspect of ancestor with PANTHER:PTN000036740" dense fibrillar component ; GO:0001651 | inferred from sequence or structural similarity with UniProtKB:P22509 small nucleolar ribonucleoprotein complex ; GO:0005732 | inferred from sequence or structural similarity box C/D snoRNP complex ; GO:0031428 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 nucleolus ; GO:0005730 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 nucleolus ; GO:0005730 | "GCR-6, pen59C5, Pen59C5, GCR6, CG9888, Fib, Fibri, fib, fibrillarin" "IPR000692:Fibrillarin, IPR020813:Fibrillarin, conserved site, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG9888 11-Aug-17 DroID_v2017_08 Drer\fbl Scer\NOP1 "Cele\C06E1.9, Cele\fib-1" Xtro\fbl "Mmus\Fbll1, Mmus\Fbl" Hsap\FBL female sterile FBgn0054047 CR34047 - http://flybase.org/reports/FBgn0054047 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1083, HDC08545, CG34047, CR34047" - CR34047 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263315 Ubi::Ecol\birA - http://flybase.org/reports/FBgn0263315 engineered_fusion_gene - - - Ubi::Ecol\birA - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022113 l(2)k06904 lethal (2) k06904 http://flybase.net/reports/FBgn0022113.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0001685 l(1)ESHS6 lethal (1) ESHS6 http://flybase.org/reports/FBgn0001685 - gene - - - l(1)ESHS6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264997 CR44148 - http://flybase.org/reports/FBgn0264997 non_protein_coding_gene - - - CR44148 - CR44148 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0008641 94Che 94Che http://flybase.org/reports/FBgn0008641 - gene - - - 94Che - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005069 fs(2)OW210 female sterile (2) OW210 http://flybase.org/reports/FBgn0005069 - gene - - - fs(2)OW210 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045823 vsg visgun http://flybase.org/reports/FBgn0045823 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype somatic ring canal ; GO:0098549 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay "CG16707, FBgn0045823, GH15083, BEST:GH15083, anon-WO0118547.164, vsg, Vsg" IPR007947:CD164-related protein CG16707 11-Aug-17 DroID_v2017_08 "Drer\cd164l2, Drer\cd164, Drer\tmem123" - Cele\C50F2.7 - "Mmus\Tmem123, Mmus\Cd164l2, Mmus\Cd164" "Hsap\CD164, Hsap\TMEM123, Hsap\CD164L2" "viable,memory defective,chemical sensitive,fertile,melanotic mass phenotype" melanotic mass FBgn0044108 E(rst)C384 E(rst)C384 http://flybase.org/reports/FBgn0044108 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C384, E(rst)C384" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0002747 min mini http://flybase.org/reports/FBgn0002747 - gene - - - "mi, min" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263114 CG43371 - http://flybase.org/reports/FBgn0263114 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43371 - CG43371 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053421 5SrRNA:CR33421 5SrRNA:CR33421 http://flybase.org/reports/FBgn0053421 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33421, 5SrRNA:CR33421" - CR33421 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085620 CG41332 - http://flybase.org/reports/FBgn0085620 protein_coding_gene - - - CG41332 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034861 CG9815 - http://flybase.org/reports/FBgn0034861 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9815 - CG9815 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary" FBgn0017390 l(1)15Da lethal (1) 15Da http://flybase.org/reports/FBgn0017390 - gene - - - l(1)15Da - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0026337 Su(tor)2-341-39 Su(tor)2-341-39 http://flybase.org/reports/FBgn0026337 - gene - - - Su(tor)2-341-39 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020324 anon-7H1 anon-7H1 http://flybase.org/reports/FBgn0020324 - gene - - - "7H1, anon-7H1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038266 CG3610 - http://flybase.org/reports/FBgn0038266 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3610 - CG3610 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031778 CR9162 - http://flybase.org/reports/FBgn0031778 non_protein_coding_gene - - - "CG9162, CR9162" - CR9162 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0064177 l(1)CB-6411-3 lethal (1) CB-6411-3 http://flybase.org/reports/FBgn0064177 gene - - - l(1)CB-6411-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036713 Mip Myoinhibiting peptide precursor http://flybase.org/reports/FBgn0036713 protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with SPR neuropeptide hormone activity ; GO:0005184 | non-traceable author statement receptor binding ; GO:0005102 | inferred from direct assay negative regulation of juvenile hormone biosynthetic process ; GO:0045968 | non-traceable author statement negative regulation of eating behavior ; GO:1903999 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "AstB-1, CG6456, Drm-MIP-5, Drm-MIP-2, Drm-MIP-4, Drm-MIP-3, Drm-MIP-1, Drm-MIP, DAP-B, MIP, Mip, AST-B, mip, Ast-B, AstB, ASB, DmMIP5, DmMIP4, DmMIP3, DmMIP2, DmMIP1, MIP-5, MIP-3, MIP-1, MIP-2, MIP-4" - CG6456 11-Aug-17 DroID_v2017_08 "Drer\inab, Drer\si:ch73-269m14.2, Drer\nefma, Drer\nefla, Drer\nefmb, Drer\viml, Drer\desma, Drer\ngs, Drer\prph, Drer\vim, Drer\LOC567924, Drer\si:dkey-33c12.3, Drer\neflb, Drer\gfap, Drer\zgc:65851, Drer\desmb, Drer\inaa" - "Cele\rec-1, Cele\nlp-8, Cele\ceh-81, Cele\nlp-15, Cele\nlp-38" "Xtro\vim.2, Xtro\des.1, Xtro\des.2, Xtro\ina, Xtro\nefh, Xtro\nefl, Xtro\krt8.2, Xtro\vim, Xtro\nif, Xtro\nefm, Xtro\prph" "Mmus\Ina, Mmus\Des, Mmus\Gfap, Mmus\Vim, Mmus\Svs3b, Mmus\Nefh, Mmus\Svs3a, Mmus\Svs2, Mmus\Prph, Mmus\Nefl, Mmus\Nefm" "Hsap\DES, Hsap\INA, Hsap\PRPH, Hsap\NEFL, Hsap\GFAP, Hsap\NEFH, Hsap\C17orf100, Hsap\VIM, Hsap\PI3" "viable,visible" "chaeta,supernumerary" FBgn0259614 B2032 - http://flybase.org/reports/FBgn0259614 gene - - - B2032 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin bristle,tarsal segment" FBgn0035000 CG13578 - http://flybase.org/reports/FBgn0035000 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13578 - CG13578 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0020550 fs(2)35Ed fs(2)35Ed http://flybase.org/reports/FBgn0020550 - gene - - - fs(2)35Ed - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020495 D2 D2 http://flybase.org/reports/FBgn0020495 - gene - - - D2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029703 CG12692 - http://flybase.org/reports/FBgn0029703 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12692 IPR011705:BTB/Kelch-associated CG12692 11-Aug-17 DroID_v2017_08 - - Cele\kel-3 - - "Hsap\KLHL31, Hsap\KLHL13, Hsap\KLHL9" viable FBgn0014145 deg degarni http://flybase.org/reports/FBgn0014145 - gene - - - deg - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "macrochaeta,microchaeta,sensillum campaniformium & wing,macrochaeta & leg,chemosensory sensory organ & proboscis" FBgn0051023 tRNA:Leu-TAG-1-2 transfer RNA:Leucine-TAG 1-2 http://flybase.org/reports/FBgn0051023 tRNA_gene CUA codon-amino acid adaptor activity ; GO:0033419 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033419 cytosol ; GO:0005829 | inferred by curator from GO:0033419 "AE002708.trna32-LeuTAG, tRNA:L:TAG:AE002708-a, CR31023, chr3R.trna38-LeuTAG, tRNA-Leu-TAG-1-2, tRNA:Leu-TAG-1-2, tRNA:CR31023" - CR31023 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016760 Ybb Y-bobbed http://flybase.org/reports/FBgn0016760 - rRNA_gene - - - "rDNA, rRNA, NO, bb[Y], Y rDNA, bb, Ybb, Y,rDNA" - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0051076 CG31076 - http://flybase.org/reports/FBgn0051076 protein_coding_gene - - - "CT19744, CG6309, CG31076" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG31076 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-237i5.4, Drer\LOC100331330, Drer\c13h10orf11" Scer\LEA1 Cele\T19D7.6 Xtro\c10orf11 Mmus\1700112E06Rik Hsap\C10orf11 "viable,body color defective" mesothoracic tergum FBgn0263884 l(3)A42 - http://flybase.org/reports/FBgn0263884 gene - - - l(3)A42 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0036486 Msh6 Msh6 http://flybase.org/reports/FBgn0036486 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000432, InterPro:IPR007695, InterPro:IPR007696, InterPro:IPR007860, InterPro:IPR007861, InterPro:IPR016151 mismatched DNA binding ; GO:0030983 | inferred from electronic annotation with InterPro:IPR000432, InterPro:IPR007695, InterPro:IPR007696, InterPro:IPR007860, InterPro:IPR007861, InterPro:IPR016151" DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000002504 meiotic mismatch repair ; GO:0000710 | inferred from mutant phenotype - "Msh6, CG7003" "IPR000432:DNA mismatch repair protein MutS, C-terminal, IPR007695:DNA mismatch repair protein MutS-like, N-terminal, IPR007696:DNA mismatch repair protein MutS, core, IPR007860:DNA mismatch repair protein MutS, connector domain, IPR007861:DNA mismatch repair protein MutS, clamp, IPR016151:DNA mismatch repair protein MutS, N-terminal, IPR015536:DNA mismatch repair protein MutS-homologue MSH6, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7003 11-Aug-17 DroID_v2017_08 "Drer\msh3, Drer\msh6" "Scer\MSH1, Scer\MSH3, Scer\MSH6" Cele\msh-6 "Xtro\msh6, Xtro\msh3" "Mmus\Msh6, Mmus\Msh3" "Hsap\MSH3, Hsap\MSH6" "viable,fertile" FBgn0262391 mir-184 mir-184 stem loop http://flybase.org/reports/FBgn0262391 miRNA_gene - "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype" - "miR-184, mir-184, dme-mir-184, 184, MIR-184, CR42925, CR33576, dme-miR-184, CR33577, mir-184*, miR-184S, mir-184S, miR-184*, dme-miR-184-3p" - CR42925 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261733 EC4056 - http://flybase.org/reports/FBgn0261733 gene - - - EC4056 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0067753 l(1)G0135 lethal (1) G0135 http://flybase.org/reports/FBgn0067753 gene - - - l(1)G0135 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265582 CR44409 - http://flybase.org/reports/FBgn0265582 non_protein_coding_gene - - - CR44409 - CR44409 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000526 dusky-body dusky body http://flybase.org/reports/FBgn0000526 - gene - - - "dusky-body, dyb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male fertile,female sterile,eye color defective,body color defective" "adult thorax,pigment cell,eye,wing" FBgn0065240 l(2)SH2156 lethal (2) SH2156 http://flybase.org/reports/FBgn0065240 gene - - - "l(2)SH2156, l(2)SH2 2156" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013524 l(2)23AB2 lethal (2) 23AB2 http://flybase.org/reports/FBgn0013524 - gene - - - "l(2)23Ae, l(2)23AB2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage,lethal" FBgn0038203 Or88a Odorant receptor 88a http://flybase.org/reports/FBgn0038203 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "88a, DOR99, 88A.1, CG14360, Or88a, or88a, DmOr88a" "IPR004117:Olfactory receptor, insect" CG14360 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069342 TAHRE\gag TAHRE element gag http://flybase.org/reports/FBgn0069342 transposable_element_gene - - - "GAG, TAHRE\gag, TAHRE gag" IPR006579:Pre-C2HC domain - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003933 snRNA:U5:14B small nuclear RNA U5 at 14B http://flybase.org/reports/FBgn0003933 FBgn0003932 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-14B, snRNA[[3]], K2, dU5, snRNA:U5, snRNA4, snRNA3, U5snRNA14B, CR32914, U5snRNA, snRNA:U5:14B, U5var:14B, U5:14B, U5 snRNA, U5 snRNA 14B, 14B U5" - CR32914 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262006 CG42824 - http://flybase.org/reports/FBgn0262006 protein_coding_gene - - - "CG42824, CG34053, HDC14119" - CG42824 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263970 CR43724 - http://flybase.org/reports/FBgn0263970 non_protein_coding_gene - - - "CR43724, lincRNA.263" - CR43724 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250738 l(3)S026909 lethal (3) S026909 http://flybase.org/reports/FBgn0250738 gene - - - "l(3)S026909, l(3)s026909" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262561 Xanthias\polyprotein - http://flybase.org/reports/FBgn0262561 transposable_element_gene - - - "Xanthias\polyprotein, polyprotein" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020849 if::mew if::mew http://flybase.org/reports/FBgn0020849 - engineered_fusion_gene - - - if::mew - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041237 Gr58c Gustatory receptor 58c http://flybase.org/reports/FBgn0041237 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr58A3, CG13491, 58A3, 58A.3, GR58A.3, Gr58c, GR58c" IPR013604:7TM chemoreceptor CG13491 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC04136 I 1.637733002 0.410606826 0.530800863 0.5626311 -0.488423637 -0.91337785 FBgn0263384 CR43436 - http://flybase.org/reports/FBgn0263384 non_protein_coding_gene - - - CR43436 - CR43436 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086712 Egm Enigma http://flybase.org/reports/FBgn0086712 protein_coding_gene "oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from electronic annotation with InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786" compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype fatty acid beta-oxidation ; GO:0006635 | inferred from mutant phenotype negative regulation of cellular response to oxidative stress ; GO:1900408 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "Egm, egm, l(2)k14708, CG9006, Acyl CoA DH" "IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal" CG9006 11-Aug-17 DroID_v2017_08 "Drer\acad8, Drer\acads, Drer\acad9, Drer\acadm, Drer\acadvl" - "Cele\acdh-8, Cele\acdh-10, Cele\acdh-11, Cele\acdh-1, Cele\acdh-7, Cele\acdh-13, Cele\acdh-4, Cele\acdh-9" "Xtro\acadsb, Xtro\acad8, Xtro\acads, Xtro\ivd, Xtro\acad9, Xtro\MGC107841, Xtro\acadm" "Mmus\Acads, Mmus\Acad9, Mmus\Acadvl, Mmus\Acadsb, Mmus\Acadm, Mmus\Ivd, Mmus\Acad8" "Hsap\ACADVL, Hsap\ACADS, Hsap\ACADM, Hsap\IVD, Hsap\ACAD8, Hsap\ACADSB, Hsap\ACAD9" DRSC22860 E -0.262340114 1.107950714 2.136550482 1.636922164 0.718444034 0.707057362 FBgn0020931 Est-E Est-E http://flybase.org/reports/FBgn0020931 - gene - - - Est-E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030017 CG2278 - http://flybase.org/reports/FBgn0030017 protein_coding_gene - - - CG2278 - CG2278 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036714 CG7692 - http://flybase.org/reports/FBgn0036714 protein_coding_gene - - - CG7692 - CG7692 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0069130 mei(2)yh217 mei(2)yh217 http://flybase.org/reports/FBgn0069130 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(2)yh217 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,meiotic cell cycle defective,male,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0267705 CR46038 - http://flybase.org/reports/FBgn0267705 non_protein_coding_gene - - - CR46038 - CR46038 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259269 EP-493 - http://flybase.org/reports/FBgn0259269 gene - - - EP-493 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0051473 CG31473 - http://flybase.org/reports/FBgn0051473 protein_coding_gene "FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR011576, InterPro:IPR012349 pyridoxamine-phosphate oxidase activity ; GO:0004733 | inferred from biological aspect of ancestor with PANTHER:PTN000852047" "pyridoxine biosynthetic process ; GO:0008615 | inferred from electronic annotation with InterPro:IPR000659 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000659, InterPro:IPR011576, InterPro:IPR012349 pyridoxal phosphate biosynthetic process ; GO:0042823 | inferred from biological aspect of ancestor with PANTHER:PTN000852047" - "CG2649, CG31473" "IPR000659:Pyridoxamine 5'-phosphate oxidase, IPR011576:Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain, IPR012349:FMN-binding split barrel" CG31473 11-Aug-17 DroID_v2017_08 Drer\pnpo Scer\PDX3 Cele\F57B9.1 Xtro\pnpo Mmus\Pnpo Hsap\PNPO viable FBgn0051269 CG31269 - http://flybase.org/reports/FBgn0051269 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP126, CG5233, CG31269" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG31269 11-Aug-17 DroID_v2017_08 "Drer\LOC560023, Drer\si:ch211-165b19.9, Drer\zgc:171509, Drer\zmp:0000001088, Drer\try" - "Cele\try-1, Cele\svh-1, Cele\nhl-3" - "Mmus\Klk1b8, Mmus\Prss55, Mmus\Klk1b16, Mmus\Klk1b4, Mmus\Klk13, Mmus\Klk1b11, Mmus\Klk10, Mmus\Klk15, Mmus\Proz, Mmus\Klk1b3, Mmus\Egfbp2, Mmus\Klk14, Mmus\Klk7" "Hsap\KLK9, Hsap\KLK14, Hsap\PROZ, Hsap\KLK7, Hsap\KLK11" viable FBgn0060596 l(3)S092012b lethal (3) S092012b http://flybase.org/reports/FBgn0060596 gene - - - "0920/12, l(3)S092012b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000209 Bpt Blackpatch http://flybase.org/reports/FBgn0000209 - gene - - - Bpt - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile,partially lethal - majority die,visible,dominant,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal" eye FBgn0051161 CG31161 - http://flybase.org/reports/FBgn0051161 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6943, CG31161" - CG31161 11-Aug-17 DroID_v2017_08 Drer\tsga10 - - - - - "viable,visible" trichogen cell DRSC25099 K -0.408154239 -0.501008354 0.604084125 -0.375322223 -1.508690417 -0.082845739 FBgn0027180 l(2)60A-N lethal (2) 60A-N http://flybase.org/reports/FBgn0027180 - gene - - - l(2)60A-N - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065117 l(3)SH158 lethal (3) SH158 http://flybase.org/reports/FBgn0065117 gene - - - "l(3)SH158, l(2)SH3 158" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003226 re-b reduced eyes b http://flybase.org/reports/FBgn0003226 - gene - - - re-b - - 11-Aug-17 DroID_v2017_08 - - - - - - "ommatidium,eye" FBgn0060535 l(3)S100502b lethal (3) S100502b http://flybase.org/reports/FBgn0060535 gene - - - "1005/02, l(3)S100502b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0013681 mt:ND3 mitochondrial NADH-ubiquinone oxidoreductase chain 3 http://flybase.org/reports/FBgn0013681 FBgn0002867 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR000440 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000440 - "CG34076, ND3, NADH3, URF3, mt:ND3, nad3" "IPR000440:NADH:ubiquinone/plastoquinone oxidoreductase, chain 3" CG34076 11-Aug-17 DroID_v2017_08 Drer\ND3 - Cele\ND3 Xtro\ND3 Mmus\ND3 Hsap\ND3 FBgn0041092 tai taiman http://flybase.org/reports/FBgn0041092 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 ligand-dependent nuclear receptor transcription coactivator activity ; GO:0030374 | inferred from direct assay steroid hormone receptor binding ; GO:0035258 | inferred from physical interaction with EcR ligand-dependent nuclear receptor binding ; GO:0016922 | inferred from biological aspect of ancestor with PANTHER:PTN000074430 "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000074430 intracellular receptor signaling pathway ; GO:0030522 | inferred from biological aspect of ancestor with PANTHER:PTN000074430 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of growth ; GO:0045927 | inferred from mutant phenotype germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype cellular response to hormone stimulus ; GO:0032870 | inferred from biological aspect of ancestor with PANTHER:PTN000074430 regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with tgo" ecdysone receptor holocomplex ; GO:0008230 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DAIB1, DmTaiman, CG13109, l(2)k05809, EP(2)2630, l(2)01351, 58/2, l(2)k05802, bs13g05.y1, TAI, NEST:bs13g05, CG18494, tai, Tai" "IPR000014:PAS domain, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017426:Nuclear receptor coactivator, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG13109 11-Aug-17 DroID_v2017_08 "Drer\arntl1b, Drer\ncoa1, Drer\clockb, Drer\ncoa2, Drer\ncoa3, Drer\arntl1a" - - "Xtro\arntl, Xtro\ncoa2" "Mmus\Clock, Mmus\Arntl2, Mmus\Ncoa1, Mmus\Arntl, Mmus\Ncoa2, Mmus\Ncoa3" "Hsap\NCOA2, Hsap\ARNTL2, Hsap\NCOA1, Hsap\NCOA3, Hsap\ARNTL" adult stage follicle cell

"neuroanatomy defective,somatic clone,lethal,recessive,maternal effect,sleep defective,lethal - all die before end of pupal stage,some die during pupal stage,smell perception defective,female limited,gravitaxis defective" "axon | somatic clone | third instar larval stage,border follicle cell,female germline stem cell,supernumerary,somatic clone,imaginal disc,germarium cap cell,embryonic/first instar larval cuticle,maternal effect,escort stem cell,germline cell,heat sensitive" FBgn0034707 MED16 Mediator complex subunit 16 http://flybase.org/reports/FBgn0034707 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from direct assay transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000996461 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity "response to heat ; GO:0009408 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity response to lipopolysaccharide ; GO:0032496 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN000996461 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay" mediator complex ; GO:0016592 | inferred from direct assay mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000996461 mediator complex ; GO:0016592 | inferred from sequence or structural similarity "Trap95, Med16, CG5465, Sin4/TRAP95, dTRAP95, MED16, med16" "IPR017986:WD40-repeat-containing domain, IPR021665:Mediator complex, subunit Med16, IPR015943:WD40/YVTN repeat-like-containing domain" CG5465 11-Aug-17 DroID_v2017_08 Drer\med16 - - Xtro\med16 Mmus\Med16 Hsap\MED16 viable DRSC26633 EK -0.216323112 -0.212411918 -1.604794216 0.820954838 1.223349538 3.473917134 FBgn0038219 CG14839 - http://flybase.org/reports/FBgn0038219 protein_coding_gene molecular_function ; GO:0003674 | no biological data available developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 cellular_component ; GO:0005575 | no biological data available CG14839 IPR007999:Protein of unknown function DUF745 CG14839 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002391 l(3)93Dh lethal (3) 93Dh http://flybase.org/reports/FBgn0002391 - gene - - - "er16, l(3)er16, l(3)93Dh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038972 CG7054 - http://flybase.org/reports/FBgn0038972 protein_coding_gene - - - CG7054 IPR008914:Phosphatidylethanolamine-binding protein CG7054 11-Aug-17 DroID_v2017_08 "Drer\mrpl38, Drer\pebp1" "Scer\MRPL35, Scer\YLR179C, Scer\TFS1" "Cele\F40A3.3, Cele\Y69E1A.5" "Xtro\mrpl38, Xtro\pebp4, Xtro\pebp1" "Mmus\Mrpl38, Mmus\Pbp2, Mmus\Pebp1, Mmus\Pebp4" "Hsap\PEBP1, Hsap\PEBP4, Hsap\MRPL38" "viable,visible" trichogen cell DRSC16185 K 0.026247332 0.174391091 0.392094207 0.43711184 0.421263102 1.78836673 FBgn0004450 stripes stripes http://flybase.org/reports/FBgn0004450 - gene - - - "stripes, str" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260298 GSd416 - http://flybase.org/reports/FBgn0260298 gene - - - GSd416 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039088 CG10164 - http://flybase.org/reports/FBgn0039088 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs02f09, CG10164" - CG10164 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,viable" "mushroom body & axon7B,Kenyon cell" FBgn0010071 Ma-dominigene Ma dominigene http://flybase.org/reports/FBgn0010071 - gene - - - "Ma-dominigene, Ma" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030581 CG14408 - http://flybase.org/reports/FBgn0030581 protein_coding_gene SH3 domain binding ; GO:0017124 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 protein kinase inhibitor activity ; GO:0004860 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 negative regulation of protein tyrosine kinase activity ; GO:0061099 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 CG14408 IPR007940:SH3-binding 5 CG14408 11-Aug-17 DroID_v2017_08 "Drer\sh3bp5b, Drer\sh3bp5lb, Drer\sh3bp5la, Drer\sh3bp5a, Drer\LOC103909186" - "Cele\rei-2, Cele\rei-1" "Xtro\sh3bp5, Xtro\sh3bp5l" "Mmus\Sh3bp5l, Mmus\Sh3bp5" "Hsap\SH3BP5L, Hsap\SH3BP5" FBgn0000937 fs(2)A7 female sterile (2) A7 http://flybase.org/reports/FBgn0000937 - gene - - - fs(2)A7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,mitotic cell cycle defective" female reproductive system FBgn0060432 l(3)S125815 lethal (3) S125815 http://flybase.org/reports/FBgn0060432 gene - - - "1258/15, l(3)S125815" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016848 l(1)N29 lethal (1) N29 http://flybase.org/reports/FBgn0016848 - gene - - - "l(1)N29, N29" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262620 CR43144 - http://flybase.org/reports/FBgn0262620 non_protein_coding_gene - - - "CR43144, CG43144, lincRNA.217" - CR43144 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051627 CG31627 - http://flybase.org/reports/FBgn0051627 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 basal RNA polymerase II transcription machinery binding ; GO:0001099 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 "NEST:bs05g10, CG31627" IPR006578:MADF domain CG31627 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0030653 CG7860 - http://flybase.org/reports/FBgn0030653 protein_coding_gene asparaginase activity ; GO:0004067 | inferred from electronic annotation with InterPro:IPR033844 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern asparagine catabolic process via L-aspartate ; GO:0033345 | inferred from sequence or structural similarity with UniProtKB:Q8VI04 autophagic cell death ; GO:0048102 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q8VI04 CG7860 "IPR000246:Peptidase T2, asparaginase 2, IPR033844:Asparaginase-like 1, metazoa, IPR029055:Nucleophile aminohydrolases, N-terminal" CG7860 11-Aug-17 DroID_v2017_08 "Drer\zgc:153169, Drer\si:dkey-103j14.5, Drer\tasp1, Drer\asrgl1, Drer\si:ch211-256m1.8" - Cele\K01G5.9 "Xtro\tasp1, Xtro\LOC100486129, Xtro\asrgl1" "Mmus\Asrgl1, Mmus\Tasp1" "Hsap\ASRGL1, Hsap\TASP1" "viable,lethal" FBgn0265516 Atal Atal http://flybase.org/reports/FBgn0265516 gene - - - Atal - - 11-Aug-17 DroID_v2017_08 - - - - - - "female semi-sterile,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0015941 fs(3)820 fs(3)820 http://flybase.org/reports/FBgn0015941 - gene - - - fs(3)820 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,mitotic cell cycle defective" FBgn0036831 CG6839 - http://flybase.org/reports/FBgn0036831 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - CG6839 "IPR001604:DNA/RNA non-specific endonuclease, IPR020821:Extracellular Endonuclease, subunit A" CG6839 11-Aug-17 DroID_v2017_08 "Drer\LOC103910196, Drer\endog, Drer\si:ch211-133n4.4, Drer\LOC100333474" Scer\NUC1 Cele\cps-6 - Mmus\Endog Hsap\ENDOG viable FBgn0016033 lnp larval nonphototactic http://flybase.org/reports/FBgn0016033 - gene - - - "lnp, Lnp" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065449 l(2)SH1404 lethal (2) SH1404 http://flybase.org/reports/FBgn0065449 gene - - - "l(2)SH1404, l(2)SH2 1404" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265924 CR44713 - http://flybase.org/reports/FBgn0265924 non_protein_coding_gene - - - CR44713 - CR44713 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263986 cd cardinal http://flybase.org/reports/FBgn0263986 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 kynurenine metabolic process ; GO:0070189 | inferred from mutant phenotype negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype positive regulation of neuron death ; GO:1901216 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000895746 lysosome ; GO:0005764 | inferred from direct assay "cd, CG6969" "IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal" CG6969 11-Aug-17 DroID_v2017_08 "Drer\epx, Drer\mpx, Drer\tpo, Drer\ptgs2b, Drer\pxdn, Drer\ptgs2a, Drer\ptgs1, Drer\igsf9bb" - "Cele\T06D8.10, Cele\skpo-3, Cele\pxn-2, Cele\skpo-2, Cele\K10B4.1, Cele\R08F11.7, Cele\C46A5.4, Cele\mlt-7, Cele\F09F3.5, Cele\pxn-1, Cele\skpo-1" "Xtro\epx, Xtro\ptgs1, Xtro\tpo, Xtro\pxdn, Xtro\mpo, Xtro\ptgs2" "Mmus\Pxdn, Mmus\Ptgs2, Mmus\Lpo, Mmus\Mpo, Mmus\Ptgs1, Mmus\Tpo, Mmus\Epx" "Hsap\PXDNL, Hsap\LPO, Hsap\PTGS2, Hsap\TPO, Hsap\EPX, Hsap\PXDN, Hsap\MPO, Hsap\PTGS1" FBgn0000259 CkIIbeta Casein kinase II beta subunit http://flybase.org/reports/FBgn0000259 FBgn0027953 protein_coding_gene protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein kinase regulator activity ; GO:0019887 | inferred from direct assay eclosion rhythm ; GO:0008062 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement cellular response to starvation ; GO:0009267 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype rhythmic behavior ; GO:0007622 | traceable author statement circadian rhythm ; GO:0007623 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype intracellular mRNA localization involved in pattern specification process ; GO:0060810 | inferred from genetic interaction with CkIIα locomotor rhythm ; GO:0045475 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype inferred from genetic interaction with orb cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay "CK2, CKII, CkII-beta, CK2beta, DmCKIIbeta, dCKII, DmCK2beta, CKIIbeta, CkIIbeta1, betaCK2, DmCkIIbeta, CKIIb, CG15224, CK II, CKII-beta1, mbu, CkII, And, CCK2, CK-IIbeta, CK-II beta, CK-2, Ds cas kin, CkIIbeta, Cask-II-b, CKII beta, dCK2beta, dCKII beta, Ckiibeta, CK2-beta, Ck-IIbeta, KC2B_DROME, ck2beta, Ck2beta, Dm-CK2-beta" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG15224 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b "Hsap\CSNK2B, Hsap\LY6G5B" "circadian rhythm defective,viable,female sterile,partially,male sterile,neuroanatomy defective,visible,lethal,recessive,behavior defective,semidominant,eclosion rhythm defective,locomotor rhythm defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die during pupal stage,circadian behavior defective" "Kenyon cell,calyx of adult mushroom body,adult mushroom body,synapse,neuromuscular junction,wing vein,peripheral nervous system,longitudinal connective,ventral nerve cord commissure,synapse | somatic clone,neuromuscular junction | somatic clone,chorion | maternal effect,embryonic/larval neuroblast,ganglion mother cell" FBgn0033074 tomboy40 tomboy40 http://flybase.org/reports/FBgn0033074 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O96008 protein channel activity ; GO:0015266 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O96008 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q75Q40 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial intermembrane space protein transporter complex ; GO:0042719 | inferred from direct assay mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from sequence or structural similarity with UniProtKB:O96008 "CG8330, tomboy40, Tomboy40" IPR027246:Eukaryotic porin/Tom40 CG8330 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-71l1.1, Drer\tomm40l, Drer\tomm40" Scer\TOM40 Cele\tomm-40 "Xtro\tomm40l, Xtro\tomm40" "Mmus\Tomm40, Mmus\Tomm40l" "Hsap\TOMM40L, Hsap\TOMM40" "viable,visible,lethal" trichogen cell FBgn0020313 anon-9C1 anon-9C1 http://flybase.org/reports/FBgn0020313 - gene - - - "9C1, anon-9C1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044394 Scim34 Sensitized chromosome inheritance modifier 34 http://flybase.org/reports/FBgn0044394 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim34 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0044093 E(rst)D187 E(rst)D187 http://flybase.org/reports/FBgn0044093 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D187, E(rst)D187" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0250871 pot papillote http://flybase.org/reports/FBgn0250871 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chitin-based cuticle attachment to epithelium ; GO:0040005 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype apical part of cell ; GO:0045177 | inferred from direct assay "pot, CG2467" IPR001507:Zona pellucida domain CG2467 11-Aug-17 DroID_v2017_08 - - "Cele\cutl-12, Cele\cutl-20, Cele\cutl-6, Cele\cutl-13, Cele\cutl-1, Cele\cutl-16, Cele\cutl-28, Cele\cutl-11, Cele\cut-6, Cele\cutl-2, Cele\cutl-24, Cele\cutl-5, Cele\dpy-1, Cele\cutl-10, Cele\cutl-8, Cele\cutl-22, Cele\cutl-7, Cele\cutl-9, Cele\cutl-4, Cele\T01D1.8, Cele\cutl-29, Cele\cutl-19, Cele\cutl-14, Cele\cut-3, Cele\cutl-15, Cele\ram-5, Cele\F46G11.6, Cele\cut-4, Cele\cutl-3, Cele\cut-1, Cele\cutl-25, Cele\cut-5, Cele\cutl-26" - - - FBgn0267891 CR46179 - http://flybase.org/reports/FBgn0267891 pseudogene_attribute - - - "CR46179, CG12717-related" - CR46179 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046642 anon-38D.3 anon-38D.3 http://flybase.org/reports/FBgn0046642 gene - - - "38D.3, anon-38D.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030590 CG9518 - http://flybase.org/reports/FBgn0030590 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo lateral inhibition ; GO:0046331 | inferred from mutant phenotype" - "CG9518, Dm GMCzeta1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9518 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0039859 CG11539 - http://flybase.org/reports/FBgn0039859 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 histone acetylation ; GO:0016573 | inferred from mutant phenotype - "NAT9, CG11539" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG11539 11-Aug-17 DroID_v2017_08 Drer\nat9 - Cele\Y67D2.5 Xtro\nat9 Mmus\Nat9 Hsap\NAT9 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0058176 CG40176 - http://flybase.org/reports/FBgn0058176 protein_coding_gene - - - CG40176 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050029 CR30029 - http://flybase.org/reports/FBgn0050029 pseudogene_attribute - - - "CG30029, CG18337, BcDNA:LP05669, CR30029, CG34226" - CR30029 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" DRSC06724 I 1.870999871 -0.459854274 0.238191942 0.616532021 -1.102323571 -0.936770881 FBgn0004050 z zeste http://flybase.org/reports/FBgn0004050 "FBtr0070435, FBpp0070419" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with mor inferred from physical interaction with p400 inferred from physical interaction with Bap170 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay "positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from direct assay ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay intercalary heterochromatin ; GO:0005725 | non-traceable author statement PRC1 complex ; GO:0035102 | traceable author statement polytene chromosome interband ; GO:0005705 | inferred from direct assay "Z, CG7803, EG:BACH59J11.3, en-bx, e(bx), z" "IPR011989:Armadillo-like helical, IPR028002:Myb/SANT-like DNA-binding domain" CG7803 11-Aug-17 DroID_v2017_08 - - - - Mmus\Rb1 Hsap\RB1 " larval stage | late third instar larval stage--prepupal stage , embryonic stage | stage >=9 , larval stage | early third instar larval stage , adult stage , pharate adult stage , embryonic stage -- adult stage , pupal stage , larval stage | third instar stage 2--P " " ring gland

, organism

, embryonic/larval digestive system | restricted

, gonad

, adult muscle system | restricted

, larval central nervous system

, embryonic/larval salivary gland

, antenna

, adult abdomen

, imaginal disc

, Malpighian tubule

, adult brain

" "viable,visible,dominant,wild-type,eye color defective,recessive,lethal" "eye,pigment cell" FBgn0000605 E(var)c101 Enhancer of variegation c101 http://flybase.org/reports/FBgn0000605 - gene - - - "E-var(3)1, E(var)c[101], E(var)c101" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant,viable,female fertile,male fertile" FBgn0069158 mcl(3)Z2138 mcl(3)Z2138 http://flybase.org/reports/FBgn0069158 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z2138 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0085468 ND-MWFE NADH dehydrogenase (ubiquinone) MWFE subunit http://flybase.org/reports/FBgn0085468 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with HGNC:7683 "CG13328, CG30057, CG17054, BcDNA:RH49308, l(2)c00093, CG34439, ND-MWFE" "IPR017384:NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1" CG34439 11-Aug-17 DroID_v2017_08 "Drer\ndufa1, Drer\ncapg" - Cele\F31D4.9 Xtro\ncapg "Mmus\Ndufa1, Mmus\Ncapg" "Hsap\NDUFA1, Hsap\NCAPG" "lethal,recessive" FBgn0261439 SdhA "Succinate dehydrogenase, subunit A (flavoprotein)" http://flybase.org/reports/FBgn0261439 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR011281, InterPro:IPR014006 electron carrier activity ; GO:0009055 | inferred from biological aspect of ancestor with PANTHER:PTN000180228 succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from biological aspect of ancestor with PANTHER:PTN000180259 succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from sequence or structural similarity with UniProtKB:P31040" "mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from biological aspect of ancestor with PANTHER:PTN000180258 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000180364 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P31040 anaerobic respiration ; GO:0009061 | inferred from biological aspect of ancestor with PANTHER:PTN000180228 electron transport chain ; GO:0022900 | inferred from mutant phenotype" "mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from biological aspect of ancestor with PANTHER:PTN000180258 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from sequence or structural similarity with UniProtKB:P31040 mitochondrion ; GO:0005739 | inferred from direct assay" "CG17246, SdhA, sdh, Sdh, scs-fp, Scs-fp, Sdha, SDH, DHSA, Sdh A" "IPR015939:Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal, IPR003952:Fumarate reductase/succinate dehydrogenase, FAD-binding site, IPR003953:FAD-dependent oxidoreductase 2, FAD binding domain, IPR011281:Succinate dehydrogenase, flavoprotein subunit, IPR014006:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, IPR027477:Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain, IPR030664:Succinate dehydrogenase/fumarate reductase/adenylylsulphate reductase, flavoprotein subunit, IPR023753:FAD/NAD(P)-binding domain" CG17246 11-Aug-17 DroID_v2017_08 Drer\sdha "Scer\OSM1, Scer\FRD1, Scer\YJL045W, Scer\SDH1" "Cele\sdha-1, Cele\sdha-2" Xtro\sdha Mmus\Sdha Hsap\SDHA DRSC07547 K 0.481089811 0.281303705 0.38404312 0.469883919 0.229441572 1.642228504 FBgn0001737 l(1)HM7 lethal (1) HM7 http://flybase.org/reports/FBgn0001737 - gene - - - l(1)HM7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0044349 ftz-f1::Hsap\NR5A1 NR5A1 http://flybase.org/reports/FBgn0044349 engineered_fusion_gene - - - ftz-f1::Hsap\NR5A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004952 1688-10Eb 1.688 satellite-related 10Eb http://flybase.org/reports/FBgn0004952 - repeat_region - - - "1.688, 1688-10E[p], 1688-10Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037326 CG14669 - http://flybase.org/reports/FBgn0037326 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR020849 molecular_function ; GO:0003674 | no biological data available" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available "CG14669, Q9VNB7" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR020849:Small GTPase superfamily, Ras type" CG14669 11-Aug-17 DroID_v2017_08 "Drer\LOC100332969, Drer\rap2ab, Drer\rap1ab, Drer\rergla, Drer\rit1, Drer\rsg1, Drer\rap2c, Drer\zgc:64022, Drer\zgc:110699, Drer\rerglb, Drer\diras1a, Drer\rasl11a, Drer\ralaa, Drer\ralab, Drer\zgc:152698, Drer\rem1, Drer\rhebl1, Drer\rras2, Drer\si:ch73-116o1.2, Drer\si:dkeyp-59c12.1, Drer\zgc:114118, Drer\gem, Drer\rras, Drer\kras, Drer\rrad, Drer\rasl11b, Drer\rap2b, Drer\ralba, Drer\rap1aa, Drer\mras, Drer\si:dkey-27j5.5, Drer\zgc:153845, Drer\hrasa, Drer\rasl10a, Drer\ralbb, Drer\nras, Drer\diras2, Drer\rheb, Drer\rasd1, Drer\rem2, Drer\diras1b, Drer\rasl12, Drer\hrasb, Drer\zgc:171704" "Scer\RAS2, Scer\RSR1, Scer\RHB1, Scer\RAS1" - "Xtro\rhebl1, Xtro\rem1, Xtro\rasd1, Xtro\rsg1, Xtro\rasl11b, Xtro\diras1, Xtro\rap1b, Xtro\rap2a, Xtro\rasl10a, Xtro\ralb, Xtro\rem2, Xtro\rala, Xtro\kras, Xtro\rergl, Xtro\hras, Xtro\LOC733456, Xtro\nras, Xtro\rap2c, Xtro\gem, Xtro\rheb, Xtro\rerg, Xtro\rasl10b, Xtro\diras2, Xtro\diras3, Xtro\rap2b, Xtro\rit1, Xtro\rap1a, Xtro\ras-dva, Xtro\rrad, Xtro\rasd2" "Mmus\Rhebl1, Mmus\Rap2b, Mmus\Kras, Mmus\Rap2a, Mmus\Rrad, Mmus\Rsg1, Mmus\Rasl11a, Mmus\Rala, Mmus\Rem1, Mmus\Rergl, Mmus\Rasl11b, Mmus\Rit1, Mmus\Rap2c, Mmus\Nras, Mmus\Rheb, Mmus\Diras2, Mmus\Rasl12, Mmus\Gm266, Mmus\Rras2, Mmus\Rasl10b, Mmus\Gem, Mmus\Rit2, Mmus\Hras, Mmus\Rap1b, Mmus\Rras, Mmus\Rasl10a, Mmus\Mras, Mmus\Rap1a, Mmus\Rem2, Mmus\Rerg, Mmus\Eras, Mmus\Rasd1, Mmus\Diras1, Mmus\Rasd2, Mmus\Ralb" "Hsap\GEM, Hsap\RIT1, Hsap\RERGL, Hsap\RAP1B, Hsap\ERAS, Hsap\RASL10B, Hsap\RAP1A, Hsap\RAP2A, Hsap\RHEBL1, Hsap\RRAS, Hsap\RASL11B, Hsap\RASL10A, Hsap\RHEB, Hsap\RRAD, Hsap\MRAS, Hsap\RALB, Hsap\RRAS2, Hsap\RAP2B, Hsap\RALA, Hsap\RASD1, Hsap\KRAS, Hsap\RASD2, Hsap\REM2, Hsap\NRAS, Hsap\RASL12, Hsap\HRAS, Hsap\DIRAS3, Hsap\RERG, Hsap\RSG1, Hsap\REM1, Hsap\DIRAS1, Hsap\RAP2C, Hsap\DIRAS2, Hsap\RASL11A, Hsap\RIT2" "viable,fertile" DRSC12255 I -0.034507484 1.706376879 1.404762645 -0.663469201 0.344725916 0.685751255 FBgn0065557 l(2)SH1000 lethal (2) SH1000 http://flybase.org/reports/FBgn0065557 gene - - - "l(2)SH1000, l(2)SH2 1000" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085572 CG41246 - http://flybase.org/reports/FBgn0085572 protein_coding_gene - - - CG41246 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013234 E(var)188 E(var)188 http://flybase.org/reports/FBgn0013234 - gene - - - E(var)188 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0026349 Su(da[lyh])22C6 Su(da[lyh])22C6 http://flybase.org/reports/FBgn0026349 - gene - - - "Su(da[lyh]), Su(da[lyh])22C6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060794 l(3)S058412 lethal (3) S058412 http://flybase.org/reports/FBgn0060794 gene - - - "0584/12, l(3)S058412" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0027155 l(3)31-1 lethal (3) 31-1 http://flybase.org/reports/FBgn0027155 - gene - - - l(3)31-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022707 Agi Aryl glucosidase incognita http://flybase.org/reports/FBgn0022707 - gene "alpha-1,4-glucosidase activity ; GO:0004558 | inferred from direct assay" - - "AGI, Agi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "electrophoretic variant,fast,slow" FBgn0030271 CG15202 - http://flybase.org/reports/FBgn0030271 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from biological aspect of ancestor with PANTHER:PTN002219240 extracellular space ; GO:0005615 | inferred from sequence model "BcDNA:GH13342, CG15202, DIGF-4" IPR029277:Single domain Von Willebrand factor type C domain CG15202 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043353 EP3104 EP3104 http://flybase.org/reports/FBgn0043353 gene - - - EP3104 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,dorsocentral bristle,scutellar bristle,trichogen cell,ectopic,tormogen cell" FBgn0263755 Su(var)3-9 Suppressor of variegation 3-9 http://flybase.org/reports/FBgn0263755 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003606, InterPro:IPR007728 histone methyltransferase activity ; GO:0042054 | inferred from direct assay histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | traceable author statement histone methyltransferase activity ; GO:0042054 | non-traceable author statement histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | inferred from direct assay" histone H3-K9 methylation ; GO:0051567 | inferred from direct assay histone methylation ; GO:0016571 | inferred from direct assay heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype gene silencing ; GO:0016458 | traceable author statement female germ-line stem cell asymmetric division ; GO:0048132 | inferred from direct assay histone methylation ; GO:0016571 | traceable author statement histone modification ; GO:0016570 | inferred from mutant phenotype histone H3-K9 methylation ; GO:0051567 | inferred from mutant phenotype chromatin organization ; GO:0006325 | non-traceable author statement heterochromatin assembly ; GO:0031507 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype chromatin silencing at telomere ; GO:0006348 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of response to gamma radiation ; GO:2001229 | inferred from mutant phenotype DNA methylation ; GO:0006306 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from direct assay "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR003606, InterPro:IPR007728, InterPro:IPR011381 chromosome, centromeric region ; GO:0000775 | traceable author statement heterochromatin ; GO:0000792 | traceable author statement heterochromatin ; GO:0000792 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay" "SU(VAR)3-9, Su(var)3-9, E(var)3-2, ptn, Su(var)306, Su(var)310, SuVar3-9, Suvar3-9, Suvar39, dSU(VAR)3-9, Su(Var)3-9, su(var)3-9, SUV39, SUV39H1, caa56376 Suvar39 Dm, Su-var(3)9, Su(var)3-902, Suvar(3)9, Su-var(3)902, Su(var) 3-9, Suv 3-9, CG6476, Su(var), Su(var)328, dSu(var)3-9, CG43664, Su(VAR)3-9" "IPR023779:Chromo domain, conserved site, IPR023780:Chromo domain, IPR000953:Chromo/chromo shadow domain, IPR001214:SET domain, IPR003616:Post-SET domain, IPR007728:Pre-SET domain, IPR011381:Histone H3-K9 methyltransferase, IPR016197:Chromo domain-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG43664 11-Aug-17 DroID_v2017_08 "Drer\suv39h1a, Drer\suv39h1b, Drer\ehmt1a, Drer\setmar, Drer\prss59.1, Drer\ehmt2, Drer\LOC103908930, Drer\prss59.2, Drer\ehmt1b, Drer\zmp:0000001088" "Scer\SET2, Scer\GCD11" "Cele\try-3, Cele\set-6, Cele\set-15, Cele\Y39G10AR.8, Cele\set-32, Cele\svh-1, Cele\try-1, Cele\set-33, Cele\set-21" "Xtro\ehmt1, Xtro\suv39h2, Xtro\ehmt2" "Mmus\Ovch2, Mmus\Suv39h1, Mmus\Ehmt2, Mmus\Ehmt1, Mmus\Tpsb2, Mmus\Setmar, Mmus\Suv39h2, Mmus\Eif2s3x" "Hsap\EHMT2, Hsap\EHMT1, Hsap\SUV39H1, Hsap\SUV39H2, Hsap\SETMAR, Hsap\PRSS48, Hsap\OVCH1, Hsap\OVCH2" "suppressor of variegation,dominant,non-suppressor of variegation,viable,enhancer of variegation,recessive,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cephalopharyngeal skeleton,maternal effect,syncytial blastoderm embryo,chromatin | maternal effect,dorsal bridge,oocyte nucleus,nurse cell & nucleus,follicle cell,ventral arm of pharyngeal sclerite,dorsal arm of pharyngeal sclerite,polytene chromosome chromocenter,polytene chromosome" FBgn0267765 CR46096 - http://flybase.org/reports/FBgn0267765 non_protein_coding_gene - - - CR46096 - CR46096 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085573 CG41247 - http://flybase.org/reports/FBgn0085573 protein_coding_gene - - - CG41247 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025702 Srpk79D Serine-arginine protein kinase at 79D http://flybase.org/reports/FBgn0025702 "FBgn0037157, FBgn0037158" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 protein kinase activity ; GO:0004672 | non-traceable author statement" intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype regulation of mRNA processing ; GO:0050684 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 presynaptic active zone ; GO:0048786 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 presynaptic active zone ; GO:0048786 | inferred from direct assay "SRPK, CG9085, BEST:CK01209, SRPK1, CK01209, atc, CG11489, Srpk79D, srpk79D" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG11489 11-Aug-17 DroID_v2017_08 "Drer\srpk1b, Drer\srpk2, Drer\srpk1a, Drer\srpk3, Drer\si:ch211-220i18.4" Scer\SKY1 Cele\spk-1 "Xtro\LOC100144966, Xtro\srpk2, Xtro\srpk1, Xtro\srpk3" "Mmus\Srpk3, Mmus\Srpk1, Mmus\Srpk2" "Hsap\SRPK1, Hsap\SRPK3, Hsap\SRPK2" "flight defective,recessive,locomotor behavior defective,short lived,neuroanatomy defective,viable,neurophysiology defective,fertile" "axon,neuron" FBgn0052580 Muc14A Mucin 14A http://flybase.org/reports/FBgn0052580 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model - extracellular matrix ; GO:0031012 | inferred from sequence model "Muc14A, CG32580" - CG32580 11-Aug-17 DroID_v2017_08 "Drer\asic2, Drer\scospondin, Drer\vwf, Drer\otogl, Drer\LOC799643" "Scer\MSB2, Scer\FLO9, Scer\FLO1, Scer\PRM7, Scer\FLO11, Scer\YMR317W, Scer\HPF1, Scer\YIL169C, Scer\HKR1, Scer\FIG2, Scer\FLO5" "Cele\H43E16.1, Cele\srap-1, Cele\ZC178.2, Cele\H02F09.3, Cele\clec-223, Cele\dpy-6" - "Mmus\Muc5ac, Mmus\Sspo, Mmus\Muc5b, Mmus\Muc2, Mmus\Vwf, Mmus\Akap13, Mmus\Muc6, Mmus\Muc4" "Hsap\MUC19, Hsap\SSPO, Hsap\MUC5B, Hsap\OTOG, Hsap\MUC16, Hsap\MUC4, Hsap\MUC2, Hsap\MUC17, Hsap\VWF, Hsap\MUC6" "viable,fertile" FBgn0000812 fs(1)K93 female sterile (1) K93 http://flybase.org/reports/FBgn0000812 - gene - - - fs(1)K93 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" egg FBgn0263492 CR43481 - http://flybase.org/reports/FBgn0263492 non_protein_coding_gene - - - CR43481 - CR43481 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025751 l(3)93Dl lethal (3) 93Dl http://flybase.org/reports/FBgn0025751 - gene - - - "E23, l(3)93Dl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035711 CG8519 - http://flybase.org/reports/FBgn0035711 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available CG8519 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR020849:Small GTPase superfamily, Ras type" CG8519 11-Aug-17 DroID_v2017_08 "Drer\kras, Drer\hrasa, Drer\rsg1, Drer\rap2b, Drer\rerg, Drer\hrasb, Drer\rras2, Drer\gem, Drer\ralaa, Drer\zgc:171704, Drer\rasd1, Drer\rerglb, Drer\rap1aa, Drer\LOC100332969, Drer\rrad, Drer\rap2ab, Drer\diras1a, Drer\rheb, Drer\ralba, Drer\zgc:153845, Drer\diras2, Drer\zgc:64022, Drer\rasl11b, Drer\rasl11a, Drer\si:ch73-116o1.2, Drer\rem1, Drer\ralab, Drer\mras, Drer\zgc:110699, Drer\rasl10a, Drer\rem2, Drer\rap1ab, Drer\rhebl1, Drer\nras, Drer\ralbb, Drer\si:dkeyp-59c12.1, Drer\si:dkey-27j5.5, Drer\zgc:114118, Drer\zgc:152698, Drer\rit1, Drer\diras1b, Drer\rras, Drer\rasl12, Drer\rap2c, Drer\rergla" "Scer\RAS1, Scer\RHB1, Scer\RAS2, Scer\RSR1" Cele\Y71F9AR.2 "Xtro\rala, Xtro\gem, Xtro\rhebl1, Xtro\rasd1, Xtro\rasl10a, Xtro\diras3, Xtro\hras, Xtro\rerg, Xtro\rasd2, Xtro\rrad, Xtro\rap2c, Xtro\rit1, Xtro\rergl, Xtro\ralb, Xtro\diras2, Xtro\nras, Xtro\rem1, Xtro\LOC733456, Xtro\diras1, Xtro\rasl11a, Xtro\rap1b, Xtro\rasl11b, Xtro\rap2a, Xtro\rem2, Xtro\ras-dva, Xtro\rap1a, Xtro\rheb, Xtro\rsg1, Xtro\kras, Xtro\rap2b" "Mmus\Rasl11b, Mmus\Gm266, Mmus\Rit2, Mmus\Rasd2, Mmus\Rrad, Mmus\Diras2, Mmus\Rasl10a, Mmus\Rsg1, Mmus\Rasl11a, Mmus\Mras, Mmus\Rap2b, Mmus\Rasl10b, Mmus\Hras, Mmus\Rap2c, Mmus\Eras, Mmus\Rergl, Mmus\Rap1a, Mmus\Rras, Mmus\Gem, Mmus\Rhebl1, Mmus\Rit1, Mmus\Ralb, Mmus\Rem1, Mmus\Rerg, Mmus\Rheb, Mmus\Rap2a, Mmus\Rasd1, Mmus\Rem2, Mmus\Rras2, Mmus\Rala, Mmus\Nras, Mmus\Rap1b, Mmus\Rasl12, Mmus\Diras1, Mmus\Kras" "Hsap\RAP1A, Hsap\RASD2, Hsap\RRAS2, Hsap\RALA, Hsap\RHEBL1, Hsap\REM1, Hsap\RASD1, Hsap\RALB, Hsap\RHEB, Hsap\RAP2C, Hsap\RERG, Hsap\DIRAS1, Hsap\REM2, Hsap\RASL11A, Hsap\RIT1, Hsap\KRAS, Hsap\RERGL, Hsap\RAP2A, Hsap\NRAS, Hsap\RAP2B, Hsap\RIT2, Hsap\RAP1B, Hsap\DIRAS3, Hsap\RASL10B, Hsap\RASL10A, Hsap\MRAS, Hsap\RSG1, Hsap\GEM, Hsap\RASL12, Hsap\RRAS, Hsap\RRAD, Hsap\ERAS, Hsap\HRAS, Hsap\DIRAS2, Hsap\RASL11B" viable FBgn0005738 l(1)TK228 lethal (1) TK228 http://flybase.org/reports/FBgn0005738 - gene - - - "l228, l(1)TK228" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "eye,lamina" FBgn0003992 vst vestar http://flybase.org/reports/FBgn0003992 - gene - - - vst - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,poor,female sterile" "wing,eye" FBgn0260329 GSd220 - http://flybase.org/reports/FBgn0260329 gene - - - GSd220 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0003711 tipF temperature-induced paralytic F http://flybase.org/reports/FBgn0003711 - gene - - - tipF - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,heat sensitive" FBgn0259562 B2015 - http://flybase.org/reports/FBgn0259562 gene - - - B2015 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,tarsal segment" FBgn0000862 fs(1)M56 female sterile (1) M56 http://flybase.org/reports/FBgn0000862 - gene - - - fs(1)M56 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage" egg FBgn0016721 Reg-7 Rhythmically expressed gene 7 http://flybase.org/reports/FBgn0016721 - gene - - - "Dreg-7, Reg-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | late , adult stage " adult head

FBgn0038806 CG5412 - http://flybase.org/reports/FBgn0038806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5412 "IPR005645:Serine hydrolase FSH, IPR029058:Alpha/Beta hydrolase fold" CG5412 11-Aug-17 DroID_v2017_08 Drer\ovca2 "Scer\FSH2, Scer\FSH3, Scer\FSH1, Scer\DFR1" "Cele\dhfr-1, Cele\C25G4.2" "Xtro\ovca2, Xtro\dhfr" "Mmus\Dhfr, Mmus\Ovca2" "Hsap\OVCA2, Hsap\DHFR" "visible,partially lethal - majority die,some die during pharate adult stage,lethal" "mesothoracic tergum,embryonic/larval brain" FBgn0024857 l(3)96Be lethal (3) 96Be http://flybase.org/reports/FBgn0024857 - gene - - - l(3)96Be - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267647 CR45985 - http://flybase.org/reports/FBgn0267647 non_protein_coding_gene - - - CR45985 - CR45985 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005255 l(3)SG74 lethal (3) SG74 http://flybase.org/reports/FBgn0005255 - gene - - - l(3)SG74 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030824 CG5070 - http://flybase.org/reports/FBgn0030824 protein_coding_gene - - - CG5070 - CG5070 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,supernumerary" FBgn0266787 CR45252 - http://flybase.org/reports/FBgn0266787 non_protein_coding_gene - - - CR45252 - CR45252 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083018 snoRNA:Psi18S-841b snoRNA:Psi18S-841b http://flybase.org/reports/FBgn0083018 snoRNA_gene - - - "snoRNA:Psi18S-841b, Psi18S-841b, psi18S-841b, CR34551, chr2R:16837876..16838002" - CR34551 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014985 l(2)46Da lethal (2) 46Da http://flybase.org/reports/FBgn0014985 - gene - - - "VII, l(2)46Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060815 l(3)S052904 lethal (3) S052904 http://flybase.org/reports/FBgn0060815 gene - - - "0529/04, l(3)S052904" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038014 CG10041 - http://flybase.org/reports/FBgn0038014 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence model" extracellular space ; GO:0005615 | inferred from direct assay "SP178, CG10041" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG10041 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.15, Drer\si:dkey-78l4.10, Drer\LOC558805, Drer\si:ch211-165b19.9, Drer\si:dkey-78l4.5, Drer\si:dkey-21e2.12, Drer\si:dkey-78l4.4, Drer\si:dkey-78l4.11" - "Cele\svh-1, Cele\try-3" - "Mmus\Gzmd, Mmus\Gzmm, Mmus\Gzmg, Mmus\Gzmn, Mmus\Prtn3, Mmus\Prss54, Mmus\Gzmf, Mmus\Mcpt4, Mmus\Ovch2, Mmus\2210010C04Rik, Mmus\Gzmb, Mmus\Gzme" "Hsap\GZMB, Hsap\OVCH1, Hsap\PRTN3, Hsap\ELANE, Hsap\ACR, Hsap\GZMM, Hsap\GZMH, Hsap\OVCH2" viable FBgn0019777 l(1)318 lethal (1) 318 http://flybase.org/reports/FBgn0019777 - gene - - - l(1)318 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,recessive" FBgn0036545 GXIVsPLA2 GXIVsPLA2 http://flybase.org/reports/FBgn0036545 protein_coding_gene "phospholipase A2 activity ; GO:0004623 | inferred from electronic annotation with InterPro:IPR010711, InterPro:IPR013090 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR010711" "lipid catabolic process ; GO:0016042 | inferred from electronic annotation with InterPro:IPR010711, InterPro:IPR013090 phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR010711 "CG17035, GXIVsPLA2, GXIVsPLA" "IPR010711:Group XII secretory phospholipase A2 precursor, IPR016090:Phospholipase A2 domain, IPR033113:Phospholipase A2, histidine active site" CG17035 11-Aug-17 DroID_v2017_08 "Drer\pla2g12a, Drer\pla2g12b" - "Cele\B0478.3, Cele\C31H1.5, Cele\F44B9.10" "Xtro\pla2g12a, Xtro\pla2g12b" "Mmus\Pla2g12a, Mmus\Pla2g12b" "Hsap\PLA2G12B, Hsap\PLA2G12A" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0033369 CG8197 - http://flybase.org/reports/FBgn0033369 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG8197 "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG8197 11-Aug-17 DroID_v2017_08 "Drer\nlrc3, Drer\lrrc45, Drer\nod1, Drer\tonsl, Drer\si:ch211-122c9.5, Drer\si:ch211-81a5.5, Drer\si:dkey-23k10.3, Drer\lrrc34, Drer\ciita, Drer\LOC101884653, Drer\nlrx1, Drer\cep78, Drer\nod2, Drer\nlrc3l" - - "Xtro\tonsl, Xtro\cep78, Xtro\lrrc45, Xtro\lrrc31, Xtro\lrrc34, Xtro\LOC100485518, Xtro\nod1, Xtro\nlrx1" "Mmus\Lrrc34, Mmus\Lrrc74b, Mmus\Nlrp4b, Mmus\Nlrp14, Mmus\Rnh1, Mmus\Nlrp4a, Mmus\Lrrc74a, Mmus\Nlrp9c, Mmus\Nlrp9b, Mmus\Lrrc71, Mmus\Nod2, Mmus\Nlrp9a, Mmus\Ciita, Mmus\Nlrp4f, Mmus\Lrrc45, Mmus\Cep78, Mmus\Nlrc3, Mmus\Tonsl, Mmus\Nod1, Mmus\Nlrx1, Mmus\Nlrp4c, Mmus\Nlrp4e, Mmus\Lrrc31" "Hsap\NLRP4, Hsap\NLRX1, Hsap\NOD2, Hsap\RNH1, Hsap\LRRC45, Hsap\CEP78, Hsap\TONSL, Hsap\NLRP9, Hsap\NLRP14, Hsap\LRRC71, Hsap\LRRC34, Hsap\CIITA, Hsap\NLRC5, Hsap\NOD1, Hsap\LRRC31, Hsap\LRRC74A" "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0051431 CG31431 - http://flybase.org/reports/FBgn0051431 protein_coding_gene - - - "CT32770, CG13414, CG31431" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2" CG31431 11-Aug-17 DroID_v2017_08 "Drer\fgfrl1b, Drer\fgfrl1a" - Cele\igcm-4 Xtro\fgfrl1 Mmus\Fgfrl1 Hsap\FGFRL1 "viable,partially lethal - majority die,some die during pupal stage" FBgn0262764 Mst77Y-15Psi Male-specific pseudogene 77Y 15 http://flybase.org/reports/FBgn0262764 pseudogene_attribute - - - Mst77Y-15Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025395 CG18838 - http://flybase.org/reports/FBgn0025395 FBgn0042161 protein_coding_gene - - - "EG:196F3.1, CG18838" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032167 CG5853 - http://flybase.org/reports/FBgn0032167 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" phagocytosis ; GO:0006909 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 CG5853 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG5853 11-Aug-17 DroID_v2017_08 "Drer\abcg4a, Drer\abcg4b, Drer\abcg8, Drer\abcg5, Drer\abcg2a, Drer\abcg2d, Drer\abcg2c, Drer\abcg1, Drer\abcg2b" "Scer\PDR5, Scer\YOL075C, Scer\PDR11, Scer\PDR15, Scer\PDR12, Scer\ADP1, Scer\AUS1, Scer\PDR10, Scer\SNQ2, Scer\PDR18" "Cele\wht-8, Cele\wht-2, Cele\wht-1, Cele\wht-7, Cele\abch-1, Cele\wht-6, Cele\wht-4, Cele\wht-5, Cele\wht-3" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg1, Mmus\Abcg2, Mmus\Abcg8, Mmus\Abcg5, Mmus\Abcg3, Mmus\Abcg4" "Hsap\ABCG4, Hsap\ABCG5, Hsap\ABCG8, Hsap\ABCG2, Hsap\ABCG1" "viable,lethal" FBgn0035601 Uev1A Ubiquitin-conjugating enzyme variant 1A http://flybase.org/reports/FBgn0035601 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with ben ubiquitin conjugating enzyme activity ; GO:0061631 | contributes_to inferred from direct assay protein polyubiquitination ; GO:0000209 | inferred from direct assay peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype protein K63-linked ubiquitination ; GO:0070534 | inferred from biological aspect of ancestor with PANTHER:PTN000629507 postreplication repair ; GO:0006301 | inferred from biological aspect of ancestor with PANTHER:PTN000629507 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000629507 UBC13-UEV1A complex ; GO:0035370 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "dUEV1a, dUev1A, DmUEV, UEV, CG10640, Uev1A, UEV1A, uev1a, Uev1a, UEV1a, dUEV1A" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG10640 11-Aug-17 DroID_v2017_08 "Drer\ube2v2, Drer\si:ch211-212o1.2, Drer\ube2v1, Drer\tmem189" Scer\MMS2 "Cele\uev-1, Cele\Y53C10A.5" "Xtro\ube2v2, Xtro\ube2v1, Xtro\tmem189" "Mmus\Tmem189, Mmus\Ube2v2, Mmus\Ube2v1" "Hsap\TMEM189, Hsap\TMEM189-UBE2V1, Hsap\UBE2V1, Hsap\UBE2V2" "lethal,lethal - all die before end of pupal stage,viable" FBgn0000698 fltD flight defective D http://flybase.org/reports/FBgn0000698 - gene - - - fltD - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,jumping defective,partially" FBgn0040967 CG18666 - http://flybase.org/reports/FBgn0040967 protein_coding_gene protein phosphatase inhibitor activity ; GO:0004864 | inferred from electronic annotation with InterPro:IPR007062 molecular_function ; GO:0003674 | no biological data available regulation of phosphoprotein phosphatase activity ; GO:0043666 | inferred from electronic annotation with InterPro:IPR007062 regulation of signal transduction ; GO:0009966 | inferred from electronic annotation with InterPro:IPR007062 cellular_component ; GO:0005575 | no biological data available CG18666 IPR007062:Protein phosphatase inhibitor 2 (IPP-2) CG18666 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016822 l(1)MZ1 lethal (1) MZ1 http://flybase.org/reports/FBgn0016822 - gene - - - "l(1)MZ1, M1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038674 CG14285 - http://flybase.org/reports/FBgn0038674 protein_coding_gene - - - CG14285 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG14285 11-Aug-17 DroID_v2017_08 - - Cele\lin-23 - - - viable FBgn0001613 l(1)dd9 lethal (1) discs degenerate 9 http://flybase.org/reports/FBgn0001613 - gene - - - "d.deg.-9, l(1)d deg-9, l(1)d.deg.9, l(1)d.deg.-9, l(1)dd9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0003630 Su(var)323 Suppressor of variegation 323 http://flybase.org/reports/FBgn0003630 - gene - - - Su(var)323 - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,viable,non-suppressor of variegation" FBgn0022397 HelI Helicase I http://flybase.org/reports/FBgn0022397 - gene ATP-dependent DNA helicase activity ; GO:0004003 | inferred from direct assay - - "dhel I, HelI" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030620 CG5662 - http://flybase.org/reports/FBgn0030620 protein_coding_gene - protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q13505 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:Q13505 CG5662 "IPR033468:Metaxin, glutathione S-transferase domain, IPR019564:Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain" CG5662 11-Aug-17 DroID_v2017_08 "Drer\faxcb, Drer\mtx2, Drer\faxca" - "Cele\cdr-2, Cele\C25H3.7, Cele\cdr-4, Cele\mtx-2, Cele\hrg-2, Cele\Y48C3A.3, Cele\cdr-6" "Xtro\mtx2, Xtro\faxc" "Mmus\Faxc, Mmus\Mtx2" "Hsap\FAXC, Hsap\MTX2" viable DRSC19957 K 0.21012613 0.021352914 0.798962988 0.345411497 1.443347485 2.077063662 FBgn0000227 Bsg25A Blastoderm-specific gene 25A http://flybase.org/reports/FBgn0000227 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | contributes_to inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from expression pattern positive regulation of chromatin silencing ; GO:0031937 | inferred from mutant phenotype chromatin silencing complex ; GO:0005677 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "bsg25A, clone 1.70, anon-EST:Liang-1.70, CG12205, Bsg25A, Elba1, Elba" IPR018379:BEN domain CG12205 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | syncytial blastoderm , embryonic stage | stage 4 " organism

viable FBgn0053431 5SrRNA:CR33431 5SrRNA:CR33431 http://flybase.org/reports/FBgn0053431 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33431, 5SrRNA:CR33431" - CR33431 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065035 AlkB AlkB http://flybase.org/reports/FBgn0065035 protein_coding_gene DNA-N1-methyladenine dioxygenase activity ; GO:0043734 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 methylcytosine dioxygenase activity ; GO:0070579 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 ferrous iron binding ; GO:0008198 | inferred from biological aspect of ancestor with PANTHER:PTN001819089 oxidative single-stranded DNA demethylation ; GO:0035552 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 RNA repair ; GO:0042245 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 nuclear euchromatin ; GO:0005719 | inferred from biological aspect of ancestor with PANTHER:PTN000421874 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000421874 "CG33250, alkB, BEST:LD02396, AlkB" "IPR027450:Alpha-ketoglutarate-dependent dioxygenase AlkB-like, IPR004574:Alkylated DNA repair protein AlkB, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG33250 11-Aug-17 DroID_v2017_08 "Drer\alkbh1, Drer\atp6v1d" - Cele\Y51H7C.5 "Xtro\alkbh1, Xtro\atp6v1d" "Mmus\Nrp, Mmus\Alkbh1, Mmus\Atp6v1d" "Hsap\ALKBH1, Hsap\ATP6V1D" viable FBgn0061164 l(1)3At lethal (1) 3At http://flybase.org/reports/FBgn0061164 gene - - - l(1)3At - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022299 l(1)M120.1 lethal (1) M120.1 http://flybase.org/reports/FBgn0022299 - gene - - - "M120.1, l(1)M120.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067354 l(3)95EFb lethal (3) 95EFb http://flybase.org/reports/FBgn0067354 gene - - - l(3)95EFb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" embryo FBgn0267960 CR46240 - http://flybase.org/reports/FBgn0267960 non_protein_coding_gene - - - "CR46240, lincRNA.507" - CR46240 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260115 2L4515 - http://flybase.org/reports/FBgn0260115 gene - - - 2L4515 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0016633 E(gl)3A Enhancer of glass 3A http://flybase.org/reports/FBgn0016633 - gene - - - E(gl)3A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065833 l(2)SH0343 lethal (2) SH0343 http://flybase.org/reports/FBgn0065833 gene - - - "l(2)SH0343, l(2)SH2 0343" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069100 mus325 mutagen-sensitive 325 http://flybase.org/reports/FBgn0069100 gene - - - mus325 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0035382 Or63a Odorant receptor 63a http://flybase.org/reports/FBgn0035382 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "63a, DOR28, 63B.1, CG9969, Or63a" "IPR004117:Olfactory receptor, insect" CG9969 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002609 E(spl)m3-HLH "Enhancer of split m3, helix-loop-helix" http://flybase.org/reports/FBgn0002609 FBgn0010046 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650 compound eye development ; GO:0048749 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" - "CG8346, m3, E(spl)-m3, E(spl)m3, HLHM3, E(Spl)-HLH-m3, E(spl)M3, HLH-m3, E(spl)C, E(spl)C m3, HLHm3, bHLHc14, E(spl)m3-HLH" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8346 11-Aug-17 DroID_v2017_08 "Drer\her3, Drer\heyl, Drer\LOC100149863, Drer\her1, Drer\her8.2, Drer\hes6, Drer\her2, Drer\her15.1, Drer\her11, Drer\her6, Drer\bhlhe40, Drer\her4.4, Drer\her8a, Drer\hes2.2, Drer\her5, Drer\helt, Drer\hey1, Drer\bhlhe41, Drer\hey2, Drer\her7, Drer\her12, Drer\her15.2, Drer\her9, Drer\her4.2, Drer\her4.3, Drer\her13, Drer\hes2.1" Scer\PHO4 "Cele\hlh-27, Cele\hlh-25, Cele\lin-22" "Xtro\bhlhe40, Xtro\hes6.1, Xtro\bhlhe41, Xtro\hes2, Xtro\hes6.2, Xtro\hes1, Xtro\hes7.1, Xtro\hey2, Xtro\hey1, Xtro\hes4, Xtro\hes7.2" "Mmus\Bhlhe40, Mmus\Heyl, Mmus\Hes7, Mmus\Hes6, Mmus\Hes1, Mmus\Hes5, Mmus\Hes2, Mmus\Hey2, Mmus\Hes3, Mmus\Bhlhe41, Mmus\Helt, Mmus\Hey1" "Hsap\HES5, Hsap\HEYL, Hsap\HEY1, Hsap\HES3, Hsap\BHLHE41, Hsap\HES7, Hsap\HEY2, Hsap\HES4, Hsap\HES1, Hsap\BHLHE40, Hsap\HES2, Hsap\HES6, Hsap\HELT" " embryonic stage | stage 13 , embryonic stage | 6-14 hr , adult stage | female " " embryonic/larval midgut | restricted

, Malpighian tubule

" "visible,lethal - all die before end of pupal stage,some die during pupal stage" "scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutellar bristle,scutum & macrochaetah-1J3" FBgn0069964 CG41048 - http://flybase.org/reports/FBgn0069964 protein_coding_gene - - - CG41048 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038179 CG9312 - http://flybase.org/reports/FBgn0038179 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay - "CT26517, CG9312" - CG9312 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0023522 CG11596 - http://flybase.org/reports/FBgn0023522 - protein_coding_gene carnosine N-methyltransferase activity ; GO:0030735 | inferred from sequence or structural similarity with UniProtKB:F1N9S8 carnosine N-methyltransferase activity ; GO:0030735 | inferred from biological aspect of ancestor with PANTHER:PTN000959318 carnosine metabolic process ; GO:0035498 | inferred from sequence or structural similarity with UniProtKB:F1N9S8 carnosine metabolic process ; GO:0035498 | inferred from biological aspect of ancestor with PANTHER:PTN000959318 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000959318 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000959318 "EG:39E1.1, CG11596" "IPR012901:N2227-like, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG11596 11-Aug-17 DroID_v2017_08 Drer\carnmt1 "Scer\YMR209C, Scer\YNL092W" Cele\Y48E1C.2 Xtro\carnmt1 Mmus\Carnmt1 Hsap\CARNMT1 "partially lethal - majority die,some die during pupal stage" FBgn0053136 CG33136 - http://flybase.org/reports/FBgn0053136 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG33136, NEST:bs04e10" - CG33136 11-Aug-17 DroID_v2017_08 - - Cele\ZC487.1 - - - DRSC05744 K 0.282007055 0.333004056 0.274885732 -0.077189528 -0.580113665 2.276284776 FBgn0027175 l(2)60Ai lethal (2) 60Ai http://flybase.org/reports/FBgn0027175 FBgn0027174 gene - - - "l(2)60i, l(2)60Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065564 l(2)SH0981 lethal (2) SH0981 http://flybase.org/reports/FBgn0065564 gene - - - "l(2)SH0981, l(2)SH2 0981" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050158 CG30158 - http://flybase.org/reports/FBgn0050158 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 "CG9464, CG15244, CG15243, BcDNA:RE28276, CG30158" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG30158 11-Aug-17 DroID_v2017_08 "Drer\zgc:171704, Drer\rap1aa, Drer\ralaa, Drer\diras2, Drer\zgc:110699, Drer\diras1b, Drer\rit1, Drer\rem2, Drer\zgc:64022, Drer\si:ch73-116o1.2, Drer\zgc:152698, Drer\hrasb, Drer\rras, Drer\ralab, Drer\diras1a, Drer\rhebl1, Drer\rap2ab, Drer\rrad, Drer\nras, Drer\rasl12, Drer\ralba, Drer\rap2b, Drer\LOC100332969, Drer\zgc:153845, Drer\si:dkey-27j5.5, Drer\hrasa, Drer\rras2, Drer\kras, Drer\zgc:114118, Drer\rergla, Drer\rap2c, Drer\rap1ab, Drer\rheb, Drer\gem, Drer\rasl11a, Drer\ralbb, Drer\si:dkeyp-59c12.1, Drer\rem1, Drer\rasl10a, Drer\mras, Drer\rasd1, Drer\rasl11b, Drer\rsg1, Drer\rerglb" "Scer\RSR1, Scer\RAS2, Scer\RHB1, Scer\RAS1" Cele\ssr-2 "Xtro\rasl11b, Xtro\rap1b, Xtro\rap1a, Xtro\gem, Xtro\ralb, Xtro\nras, Xtro\rasd2, Xtro\diras2, Xtro\rala, Xtro\rerg, Xtro\diras1, Xtro\rrad, Xtro\rap2c, Xtro\rhebl1, Xtro\ras-dva, Xtro\rit1, Xtro\rasl10a, Xtro\rap2b, Xtro\rergl, Xtro\kras, Xtro\rasd1, Xtro\rem2, Xtro\LOC733456, Xtro\rem1, Xtro\rsg1, Xtro\diras3, Xtro\hras, Xtro\rap2a, Xtro\rheb" "Mmus\Rsg1, Mmus\Rap2b, Mmus\Rala, Mmus\Nras, Mmus\Rasl10b, Mmus\Rhebl1, Mmus\Mras, Mmus\Rras2, Mmus\Eras, Mmus\Hras, Mmus\Rerg, Mmus\Diras2, Mmus\Rasd1, Mmus\Rap1a, Mmus\Rras, Mmus\Rit2, Mmus\Rit1, Mmus\Rasl10a, Mmus\Rap2a, Mmus\Rem2, Mmus\Rap2c, Mmus\Rap1b, Mmus\Gem, Mmus\Rergl, Mmus\Rem1, Mmus\Ralb, Mmus\Rasl11a, Mmus\Rasl12, Mmus\Rheb, Mmus\Gm266, Mmus\Kras, Mmus\Rasl11b, Mmus\Diras1, Mmus\Rrad, Mmus\Rasd2" "Hsap\RALB, Hsap\RASL12, Hsap\KRAS, Hsap\RIT2, Hsap\RALA, Hsap\DIRAS3, Hsap\RRAD, Hsap\RRAS2, Hsap\RAP1B, Hsap\RASD2, Hsap\DIRAS1, Hsap\NRAS, Hsap\RHEB, Hsap\RERGL, Hsap\HRAS, Hsap\RASD1, Hsap\MRAS, Hsap\RASL11B, Hsap\GEM, Hsap\DIRAS2, Hsap\RIT1, Hsap\RHEBL1, Hsap\RERG, Hsap\REM1, Hsap\RAP1A, Hsap\REM2, Hsap\RASL11A, Hsap\RAP2A, Hsap\RSG1, Hsap\RASL10A, Hsap\RAP2C, Hsap\ERAS, Hsap\RASL10B, Hsap\RAP2B, Hsap\RRAS" viable FBgn0030616 RpL37a Ribosomal protein L37a http://flybase.org/reports/FBgn0030616 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR018267 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR011332, InterPro:IPR018267 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR018267 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "CG9091, RpL37, RpL37a, RpL37A" "IPR018267:Ribosomal protein L37e, conserved site, IPR011331:Ribosomal protein L37ae/L37e, IPR011332:Zinc-binding ribosomal protein, IPR001569:Ribosomal protein L37e" CG9091 11-Aug-17 DroID_v2017_08 Drer\rpl37 "Scer\RPL37B, Scer\RPL37A" "Cele\rpl-37, Cele\W01D2.1" Xtro\rpl37 "Mmus\Rpl37, Mmus\Rpl37rt" Hsap\RPL37 DRSC21646 IEK 2.623496224 -1.228223652 1.381275095 -3.479774948 1.152827343 3.696013203 FBgn0040079 pkaap pkaap http://flybase.org/reports/FBgn0040079 protein_coding_gene - protein localization ; GO:0008104 | inferred from biological aspect of ancestor with PANTHER:PTN000322519 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000994571 "CG4132, BG:DS02740.4, DS02740.4, pkaap" IPR016137:RGS domain CG4132 11-Aug-17 DroID_v2017_08 Drer\akap10 Scer\RAX1 Cele\rgs-5 Xtro\akap10 Mmus\Akap10 Hsap\AKAP10 "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0040131 l(2)22Ah lethal (2) 22Ah http://flybase.org/reports/FBgn0040131 gene - - - "B, l(2)22Ah" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011554 etaTry etaTrypsin http://flybase.org/reports/FBgn0011554 FBgn0014415 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence or structural similarity serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP57, DmEtaTry, 169C4S, etaTry, anon-sts17, ESTS:169C4S, CG12386" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG12386 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-33m11.7, Drer\zmp:0000001088" - "Cele\try-1, Cele\svh-1" - "Mmus\Tmprss11c, Mmus\Prss55" Hsap\TMPRSS11B viable FBgn0283503 Neurl4 Neuralized E3 ubiquitin protein ligase 4 http://flybase.org/reports/FBgn0283503 protein_coding_gene - oogenesis ; GO:0048477 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay "CG46284, blue, CG6451, Neurl4, Blue" - CG46284 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004752 l(3)89Be lethal (3) 89Be http://flybase.org/reports/FBgn0004752 - gene - - - l(3)89Be - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265846 CR44635 - http://flybase.org/reports/FBgn0265846 non_protein_coding_gene - - - CR44635 - CR44635 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015759 MHC95F-associated-protein MHC95F-associated protein http://flybase.org/reports/FBgn0015759 - gene - - - MHC95F-associated-protein - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016856 l(1)N37 lethal (1) N37 http://flybase.org/reports/FBgn0016856 - gene - - - "l(1)N37, N37" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027191 l(2)60A-A lethal (2) 60A-A http://flybase.org/reports/FBgn0027191 - gene - - - l(2)60A-A - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052551 CG32551 - http://flybase.org/reports/FBgn0052551 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32551 - CG32551 11-Aug-17 DroID_v2017_08 - - - - - - DRSC19260 E 0.371493573 0.316207893 -1.728945125 0.398283993 0.069789337 0.27659687 FBgn0004967 plph polyphase http://flybase.org/reports/FBgn0004967 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "plp, plph" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0082575 CycA::tor CycA::tor http://flybase.org/reports/FBgn0082575 engineered_fusion_gene - - - CycA::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - mitotic cell cycle defective S phase | ectopichs.2sev FBgn0032968 CG11634 - http://flybase.org/reports/FBgn0032968 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT09142, CG11634" IPR009961:Protein of unknown function DUF1487 CG11634 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039769 CG15534 - http://flybase.org/reports/FBgn0039769 protein_coding_gene sphingomyelin phosphodiesterase activity ; GO:0004767 | inferred from electronic annotation with InterPro:IPR011160 sphingomyelin catabolic process ; GO:0006685 | inferred from electronic annotation with InterPro:IPR011160 - "aSMase, CG15534, alphaSmase" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR008139:Saposin B type domain, IPR011160:Sphingomyelin phosphodiesterase, IPR029052:Metallo-dependent phosphatase-like" CG15534 11-Aug-17 DroID_v2017_08 Drer\smpd1 Scer\PPN1 "Cele\asm-2, Cele\ZK856.5, Cele\asm-3, Cele\asm-1" - Mmus\Smpd1 Hsap\SMPD1 viable FBgn0037485 CG14606 - http://flybase.org/reports/FBgn0037485 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 phagocytosis ; GO:0006909 | inferred from mutant phenotype hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG14606 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG14606 11-Aug-17 DroID_v2017_08 "Drer\slc2a6, Drer\slc2a8, Drer\LOC101882338, Drer\slc2a13b, Drer\slc2a10, Drer\slc2a12" "Scer\YFL040W, Scer\ITR2, Scer\HXT10, Scer\HXT4, Scer\HXT17, Scer\HXT14, Scer\MPH2, Scer\ITR1, Scer\VBA2, Scer\HXT3, Scer\HXT5, Scer\AZR1, Scer\SNF3, Scer\VBA1, Scer\ATR1, Scer\YMR279C, Scer\VBA3, Scer\HXT11, Scer\VBA4, Scer\YDL199C, Scer\HXT6, Scer\MAL31, Scer\HXT15, Scer\STL1, Scer\HXT16, Scer\HXT9, Scer\VBA5, Scer\MAL11, Scer\SGE1, Scer\GEX1, Scer\HXT7, Scer\ENB1, Scer\HXT13, Scer\YDR387C, Scer\HXT1, Scer\RGT2, Scer\GEX2, Scer\MPH3, Scer\GAL2, Scer\HXT8, Scer\HXT2" - "Xtro\slc2a10, Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a12" "Mmus\Slc2a13, Mmus\Slc2a6, Mmus\Slc2a12, Mmus\Slc2a8, Mmus\Slc2a10" "Hsap\SLC2A12, Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SLC2A8, Hsap\SLC2A10" viable FBgn0037447 Neurochondrin Neurochondrin http://flybase.org/reports/FBgn0037447 protein_coding_gene molecular_function ; GO:0003674 | no biological data available muscle system process ; GO:0003012 | inferred from expression pattern inferred from genetic interaction with Mhc neuronal cell body ; GO:0043025 | inferred from sequence or structural similarity with UniProtKB:O35095 dendrite ; GO:0030425 | inferred from sequence or structural similarity with UniProtKB:O35095 "Neurochondrin, CG2330" "IPR008709:Neurochondrin, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG2330 11-Aug-17 DroID_v2017_08 Drer\ncdn - - Xtro\ncdn Mmus\Ncdn Hsap\NCDN FBgn0027120 l(3)rI327 lethal (3) rI327 http://flybase.org/reports/FBgn0027120 - gene - - - "l(?)rI327, l(3)rI327" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013253 E(var)3-7 E(var)3-7 http://flybase.org/reports/FBgn0013253 - gene - - - "E-var(3)7, E(var)3-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0014104 anon-4Cc anon-4Cc http://flybase.org/reports/FBgn0014104 - gene - - - "T7, anon-4Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | 0-3 hr FBgn0060446 l(3)S122407b lethal (3) S122407b http://flybase.org/reports/FBgn0060446 gene - - - "1224/07, l(3)S122407b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0266498 s-167 - http://flybase.org/reports/FBgn0266498 gene - - - s-167 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267600 CR45938 - http://flybase.org/reports/FBgn0267600 non_protein_coding_gene - - - CR45938 - CR45938 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053806 His3:CG33806 His3:CG33806 http://flybase.org/reports/FBgn0053806 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33806, His3:CG33806" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33806 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-429i10.3, Drer\zgc:113984, Drer\zgc:113983, Drer\cenpa, Drer\zgc:173552, Drer\h3f3b.1, Drer\LOC108190747, Drer\si:ch73-36p18.2, Drer\hist2h3c, Drer\h3f3d, Drer\h3f3a, Drer\hist2h3ca1, Drer\si:dkey-23a13.8, Drer\h3f3c, Drer\LOC108190746" "Scer\CSE4, Scer\HHT2, Scer\HHT1" "Cele\his-25, Cele\his-70, Cele\his-69, Cele\his-72, Cele\his-74, Cele\his-9, Cele\his-6, Cele\his-2, Cele\his-55, Cele\his-32, Cele\his-13, Cele\his-27, Cele\his-45, Cele\his-49, Cele\his-42, Cele\his-71, Cele\his-63, Cele\his-17, Cele\his-59" "Xtro\hist2h3d, Xtro\h3f3b, Xtro\LOC100487756, Xtro\cenpa" "Mmus\Hist1h3c, Mmus\Cenpa, Mmus\Hist1h3h, Mmus\Hist1h3i, Mmus\Hist1h3g, Mmus\Hist2h3b, Mmus\Hist1h3d, Mmus\H3f3b, Mmus\H3f3a, Mmus\Hist2h3c1, Mmus\Hist1h3a, Mmus\Hist2h3c2, Mmus\Hist1h3b, Mmus\Hist1h3e, Mmus\Hist1h3f" "Hsap\H3F3C, Hsap\HIST1H3D, Hsap\HIST1H3E, Hsap\HIST1H3A, Hsap\HIST1H3H, Hsap\HIST1H3J, Hsap\HIST1H3C, Hsap\H3F3A, Hsap\HIST1H3F, Hsap\HIST1H3B, Hsap\HIST3H3, Hsap\CENPA, Hsap\HIST2H3A, Hsap\HIST2H3D, Hsap\HIST1H3G, Hsap\HIST2H3C, Hsap\HIST1H3I, Hsap\H3F3B" FBgn0265910 CR44699 - http://flybase.org/reports/FBgn0265910 non_protein_coding_gene - - - "lincRNA.39, CR44699" - CR44699 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039055 Rassf Ras association family member http://flybase.org/reports/FBgn0039055 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 protein binding ; GO:0005515 | inferred from physical interaction with hpo response to gamma radiation ; GO:0010332 | inferred from mutant phenotype negative regulation of signal transduction ; GO:0009968 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype - "Rassf, dRASSF, CG4656, dmRASSF, RASSF, dRassf" "IPR000159:Ras-associating (RA) domain, IPR001781:Zinc finger, LIM-type, IPR011524:SARAH domain, IPR029071:Ubiquitin-related domain, IPR033614:C-terminal RASSF family" CG4656 11-Aug-17 DroID_v2017_08 "Drer\mical2a, Drer\rassf6, Drer\mical1, Drer\rassf4, Drer\crip1, Drer\mical3a, Drer\rassf2b, Drer\rassf2a, Drer\mical3b, Drer\rassf3, Drer\mical2b" Scer\ATP14 "Cele\rsf-1, Cele\valv-1, Cele\exc-9" "Xtro\rassf2, Xtro\mical2, Xtro\rassf3, Xtro\rassf4, Xtro\crip1, Xtro\rassf5, Xtro\rassf6, Xtro\rassf1, Xtro\mical3" "Mmus\Rassf6, Mmus\Mical1, Mmus\Rassf5, Mmus\Rassf4, Mmus\Mical2, Mmus\Mical3, Mmus\Rassf2, Mmus\Rassf3, Mmus\Rassf1, Mmus\Crip1" "Hsap\MICAL3, Hsap\MICAL1, Hsap\RASSF1, Hsap\MICAL2, Hsap\RASSF3, Hsap\CRIP1, Hsap\RASSF6, Hsap\RASSF2, Hsap\RASSF4" "viable,radiation sensitive,fertile,small body" wing FBgn0013266 E(var)A1 E(var)A1 http://flybase.org/reports/FBgn0013266 - gene - - - E(var)A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0266511 s-477 - http://flybase.org/reports/FBgn0266511 gene - - - s-477 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033816 CG4679 - http://flybase.org/reports/FBgn0033816 protein_coding_gene ribosomal small subunit binding ; GO:0043024 | inferred from sequence or structural similarity with UniProtKB:Q96EY7 rRNA binding ; GO:0019843 | inferred from sequence or structural similarity with UniProtKB:Q96EY7 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:Q96EY7 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q96EY7 "CG4679, RE17985p" "IPR002885:Pentatricopeptide repeat, IPR011990:Tetratricopeptide-like helical domain" CG4679 11-Aug-17 DroID_v2017_08 Drer\ptcd3 - Cele\let-630 Xtro\ptcd3 Mmus\Ptcd3 Hsap\PTCD3 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0043556 Su(ro[DOM])3023 Su(ro[DOM])3023 http://flybase.org/reports/FBgn0043556 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])3023 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051658 Nnf1b Nnf1b http://flybase.org/reports/FBgn0051658 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic metaphase plate congression ; GO:0007080 | inferred from genetic interaction with Nnf1a chromosome segregation ; GO:0007059 | inferred from genetic interaction with Nnf1a NMS complex ; GO:0031617 | inferred from sequence or structural similarity with HGNC:9112 kinetochore ; GO:0000776 | inferred from direct assay Ndc80 complex ; GO:0031262 | inferred from direct assay "Nnf1b, CG31658, dmNnf1R-1" - CG31658 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage" "metaphase,mesothoracic tergum" FBgn0020502 CU31.4 Cible d'Ubx 31.4 http://flybase.org/reports/FBgn0020502 - gene - - - "31.4, CU31.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011629 l(2)T57b4 lethal (2) T57b4 http://flybase.org/reports/FBgn0011629 FBgn0005177 gene - - - l(2)T57b4 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069205 l(2)46Di lethal (2) 46Di http://flybase.org/reports/FBgn0069205 gene - - - l(2)46Di - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,dominant" wing FBgn0261521 stich1 sticky ch1 http://flybase.org/reports/FBgn0261521 gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003650 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "peripheral nervous system development ; GO:0007422 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650" - "sticky ch-1, sticky ch1-1, 1437/02, sticky ch, stich1" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "neuron,chordotonal organ" FBgn0033564 Pex6 Peroxin 6 http://flybase.org/reports/FBgn0033564 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960" peroxisome organization ; GO:0007031 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8859 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8859 "CG30019, DmCG11919, CG11919, Pex6, DmelPex6, PEX6" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG11919 11-Aug-17 DroID_v2017_08 "Drer\pex6, Drer\hao1" Scer\PEX6 "Cele\prx-1, Cele\F41E6.5, Cele\prx-6" - Mmus\Pex6 Hsap\PEX6 "viable,fertile" FBgn0037972 CG10005 - http://flybase.org/reports/FBgn0037972 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE59626, CG10005" IPR001507:Zona pellucida domain CG10005 11-Aug-17 DroID_v2017_08 - - "Cele\cutl-10, Cele\cutl-20, Cele\cutl-2, Cele\ram-5, Cele\cut-6, Cele\cutl-25, Cele\cutl-16, Cele\cutl-6, Cele\cut-1, Cele\cutl-22, Cele\cutl-13, Cele\cut-4, Cele\cutl-11, Cele\cutl-24, Cele\dpy-1, Cele\cut-3, Cele\cutl-9, Cele\cutl-4, Cele\cutl-14, Cele\cutl-28, Cele\F46G11.6, Cele\cutl-26, Cele\T01D1.8, Cele\cutl-12, Cele\cutl-19, Cele\cutl-3, Cele\cutl-5, Cele\cutl-15, Cele\cut-5, Cele\cutl-7, Cele\cutl-29, Cele\cutl-8, Cele\cutl-1" - - - viable FBgn0036886 CG9300 - http://flybase.org/reports/FBgn0036886 protein_coding_gene - - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012584 CG9300 "IPR012584:NUC205, IPR015943:WD40/YVTN repeat-like-containing domain" CG9300 11-Aug-17 DroID_v2017_08 Drer\nol11 - - - Mmus\Nol11 Hsap\NOL11 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027864 Ogg1 8-oxoguanine DNA glycosylase http://flybase.org/reports/FBgn0027864 - protein_coding_gene oxidized purine nucleobase lesion DNA N-glycosylase activity ; GO:0008534 | inferred from electronic annotation with InterPro:IPR012904 damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR012904 DNA N-glycosylase activity ; GO:0019104 | inferred from biological aspect of ancestor with PANTHER:PTN000028425 nucleotide-excision repair ; GO:0006289 | inferred from electronic annotation with InterPro:IPR012904 base-excision repair ; GO:0006284 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype - "CG1795, dOGG1, BcDNA:LD19945, Ogg1, 1795, dOgg1" "IPR003265:HhH-GPD domain, IPR011257:DNA glycosylase, IPR012904:8-oxoguanine DNA glycosylase, N-terminal, IPR023170:Helix-turn-helix, base-excision DNA repair, C-terminal" CG1795 11-Aug-17 DroID_v2017_08 Drer\ogg1 Scer\OGG1 - Xtro\ogg1 Mmus\Ogg1 Hsap\OGG1 "viable,fertile" FBgn0031851 Aatf Apoptosis antagonizing transcription factor http://flybase.org/reports/FBgn0031851 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of programmed cell death ; GO:0043069 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000399853 oogenesis ; GO:0048477 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9NY61 "CG11188, anon-WO0118547.190, Aatf, AATF, Che-1, nutmeg" "IPR012617:Apoptosis-antagonizing transcription factor, C-terminal, IPR025160:AATF leucine zipper-containing domain" CG11188 11-Aug-17 DroID_v2017_08 Drer\aatf Scer\BFR2 Cele\Y73E7A.2 Xtro\aatf Mmus\Aatf Hsap\AATF "lethal,cell polarity defective,germline clone,viable,female sterile,partially lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "egg chamber,germline clone,oocyte,centrosome | germline clone,polar follicle cell,supernumerary,embryonic/larval neuroblast,ganglion mother cell" FBgn0025010 E(dpp)66C E(dpp)66C http://flybase.org/reports/FBgn0025010 - gene - - - E(dpp)66C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011064 l(1)Q17 lethal (1) Q17 http://flybase.org/reports/FBgn0011064 FBgn0010210 gene - - - l(1)Q17 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065181 l(3)SH002 lethal (3) SH002 http://flybase.org/reports/FBgn0065181 gene - - - "l(3)SH002, l(2)SH3 002" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019756 l(1)75B4 lethal (1) 75B4 http://flybase.org/reports/FBgn0019756 - gene - - - l(1)75B4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000098 aor abdominal one reduced http://flybase.org/reports/FBgn0000098 - gene - - - aor - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" abdominal segment 1 FBgn0041720 snRNA:U2:34ABc small nuclear RNA U2 at 34ABc http://flybase.org/reports/FBgn0041720 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay "U2:34ABc, U2, dU2, U2 snRNA, U2-34ABc, K6, snRNA:U2, U2snRNA, CR33788, snRNA:U2:34ABc, 34B U2" - CR33788 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065411 l(2)SH1567 lethal (2) SH1567 http://flybase.org/reports/FBgn0065411 gene - - - "l(2)SH1567, l(2)SH2 1567" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015891 anon-77Fa anon-77Fa http://flybase.org/reports/FBgn0015891 - gene - - - "13a, anon-77Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010641 l(2)07806 lethal (2) 07806 http://flybase.net/reports/FBgn0010641.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0038170 CG14367 - http://flybase.org/reports/FBgn0038170 protein_coding_gene - cilium assembly ; GO:0060271 | inferred from sequence model - CG14367 "IPR023379:ADP-ribosylation factor-like 2-binding protein, domain" CG14367 11-Aug-17 DroID_v2017_08 Drer\cfap36 - Cele\cfap-36 Xtro\cfap36 Mmus\Cfap36 Hsap\CFAP36 FBgn0054039 CG34039 - http://flybase.org/reports/FBgn0054039 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1005, CG34039" IPR017920:COMM domain CG34039 11-Aug-17 DroID_v2017_08 Drer\commd4 - Cele\T28F2.2 Xtro\commd4 Mmus\Commd4 "Hsap\COMMD7, Hsap\COMMD4" FBgn0038107 CG17327 - http://flybase.org/reports/FBgn0038107 protein_coding_gene aminoacyl-tRNA hydrolase activity ; GO:0004045 | inferred from electronic annotation with InterPro:IPR002833 - - CG17327 "IPR023476:Peptidyl-tRNA hydrolase II domain, IPR002833:Peptidyl-tRNA hydrolase, PTH2" CG17327 11-Aug-17 DroID_v2017_08 "Drer\ptrh2, Drer\si:dkey-19e4.5" Scer\PTH2 Cele\C24G6.8 Xtro\ptrh2 Mmus\Ptrh2 Hsap\PTRH2 FBgn0267563 CR45903 - http://flybase.org/reports/FBgn0267563 non_protein_coding_gene - - - CR45903 - CR45903 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259481 Mob2 Mob2 http://flybase.org/reports/FBgn0259481 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NBK5 protein kinase binding ; GO:0019901 | inferred from physical interaction with trc long-term memory ; GO:0007616 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay cell hair ; GO:0070451 | inferred from direct assay cell periphery ; GO:0071944 | inferred from direct assay "Mob1, CG11711, DMob2, dmob2, BEST:GH06341, CG11712, BcDNA:GH13236, Mob2, Dmob2, Dmob1, gh06341, MobI, trezor" IPR005301:MOB kinase activator family CG11711 11-Aug-17 DroID_v2017_08 "Drer\mob2b, Drer\LOC799520, Drer\mob1a, Drer\mob1ba, Drer\mob1bb, Drer\mob2a" "Scer\MOB2, Scer\MOB1" Cele\F09A5.4 "Xtro\mob1b, Xtro\mob1a, Xtro\mob2.1, Xtro\mob2.2" "Mmus\Mob2, Mmus\Mob1b, Mmus\Mob1a" "Hsap\MOB1A, Hsap\MOB1B, Hsap\MOB2" FBgn0002112 l(2)ax lethal (2) ax http://flybase.org/reports/FBgn0002112 - gene - - - l(2)ax - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0002780 mod modulo http://flybase.org/reports/FBgn0002780 FBgn0011255 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with nej cell proliferation ; GO:0008283 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with nej "0952/14, ms(3)100EF, CG2050, mod, Mod" IPR000504:RNA recognition motif domain CG2050 11-Aug-17 DroID_v2017_08 - - - - Mmus\Ncl Hsap\NCL " embryonic stage | stage 9 , embryonic stage | cellular blastoderm , embryonic stage | stage 10-12 , embryonic stage | stage 15 , embryonic stage | stage 8-10 , embryonic stage " " procephalic segment

, posterior embryonic/larval midgut

, visceral mesoderm

, mitotic domain 1,2,4,5,6,10,13,22,23

, cephalopharyngeal skeleton

, anterior embryonic/larval midgut

, head

, anal pad

, somatic mesoderm

, head mesoderm

, larval muscle system

, mesoderm

" "developmental rate defective,decreased cell size,viable,male sterile,Minute,male semi-sterile,recessive,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,polyphasic,suppressor of variegation,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,cell autonomous,somatic clone,lethal - all die before end of P-stage,some die during pharate adult stage,increased cell death,increased cell size,mitotic cell cycle defective" "embryonic maxillary segment,embryonic mandibular segment,adult head,somatic clone,macrochaeta,somatic muscle,embryonic/larval posterior spiracle,embryonic labial segment,adult thorax,leg,adult abdomen,adult thorax & macrochaeta | somatic clone | cell autonomous,cell autonomous,embryonic/larval midgut" FBgn0011069 l(1)Q22 lethal (1) Q22 http://flybase.org/reports/FBgn0011069 FBgn0010210 gene - - - l(1)Q22 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039469 TwdlC TweedleC http://flybase.org/reports/FBgn0039469 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlF chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlF proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlF "TwdlC, CG14254" IPR004145:Domain of unknown function DUF243 CG14254 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0022976 shoc short circuit http://flybase.org/reports/FBgn0022976 - gene - - - shoc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040213 fs(?)BP73 fs(?)BP73 http://flybase.org/reports/FBgn0040213 gene - - - fs(?)BP73 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0033659 Damm Death associated molecule related to Mch2 caspase http://flybase.org/reports/FBgn0033659 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity with Dredd inferred from sequence or structural similarity with Dronc inferred from sequence or structural similarity with Strica inferred from sequence or structural similarity with HGNC:1503 inferred from direct assay cysteine-type endopeptidase activity involved in apoptotic process ; GO:0097153 | inferred from biological aspect of ancestor with PANTHER:PTN000047947 larval midgut histolysis ; GO:0035069 | inferred from electronic annotation with InterPro:IPR033176 programmed cell death ; GO:0012501 | inferred from genetic interaction with hid proteolysis ; GO:0006508 | inferred from direct assay apoptotic process ; GO:0006915 | inferred from direct assay programmed cell death ; GO:0012501 | traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with Strica cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000047947 "Damm/Daydream, Daydream, CG18188, damm, DAMM, Damm" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR015917:Peptidase C14A, caspase catalytic domain, IPR033176:Caspase DECAY, IPR029030:Caspase-like domain" CG18188 11-Aug-17 DroID_v2017_08 "Drer\caspxa, Drer\casp6l1, Drer\si:ch211-195h23.3, Drer\caspb, Drer\LOC798445, Drer\LOC101886133, Drer\pea15, Drer\caspa, Drer\casp7, Drer\cflara, Drer\gbp3, Drer\casp8l1, Drer\LOC100331324, Drer\zgc:171731, Drer\casp6l2, Drer\caspbl, Drer\casp8l2, Drer\casp9, Drer\casp3b, Drer\casp2, Drer\casp8, Drer\casp3a, Drer\casp6" - "Cele\csp-2, Cele\ced-3, Cele\csp-1" "Xtro\pea15, Xtro\casp9, Xtro\casp2, Xtro\casp7, Xtro\casp6, Xtro\casp3, Xtro\LOC733553, Xtro\casp10, Xtro\casp1" "Mmus\Casp8, Mmus\Pea15a, Mmus\Casp9, Mmus\Casp7, Mmus\Casp14, Mmus\Casp3, Mmus\Casp6, Mmus\Casp2, Mmus\Casp1, Mmus\Casp4, Mmus\Cflar, Mmus\Pycard, Mmus\Casp12" "Hsap\CASP6, Hsap\CASP7, Hsap\CARD18, Hsap\CFLAR, Hsap\CASP14, Hsap\CASP1, Hsap\PYCARD, Hsap\PEA15, Hsap\CASP2, Hsap\CASP8, Hsap\CARD16, Hsap\CASP9, Hsap\CASP10, Hsap\CASP5, Hsap\CARD17, Hsap\CASP3, Hsap\CASP4, Hsap\CARD8" "viable,fertile,visible,increased cell death" "eye,ommatidium" FBgn0259472 EP-140 - http://flybase.org/reports/FBgn0259472 gene - - - EP-140 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing,wing vein" FBgn0061142 l(3)S000616c lethal (3) S000616c http://flybase.org/reports/FBgn0061142 gene - - - "0006/16, l(3)S000616c" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260497 l(3)12563 - http://flybase.org/reports/FBgn0260497 gene - - - l(3)12563 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective dendritic arborizing neuron FBgn0265158 CG44227 - http://flybase.org/reports/FBgn0265158 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44227 - CG44227 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022971 snRNP54K snRNP54K http://flybase.org/reports/FBgn0022971 - gene - - - "54K, snRNP54K" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024572 l(3)L7321 lethal (3) L7321 http://flybase.org/reports/FBgn0024572 - gene - - - l(3)L7321 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003027 ovl ovaless http://flybase.org/reports/FBgn0003027 - gene - - - ovl - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,female sterile" "eye,abdomen,female,ovary" FBgn0267883 CR46171 - http://flybase.org/reports/FBgn0267883 pseudogene_attribute - - - "CR46171, CG12717-related" - CR46171 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262527 nsl1 non-specific lethal 1 http://flybase.org/reports/FBgn0262527 protein_coding_gene core promoter binding ; GO:0001047 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Rcd5 histone acetyltransferase binding ; GO:0035035 | inferred from physical interaction with mof "mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from genetic interaction with nos larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from genetic interaction with nos regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from genetic interaction with nos" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay NSL complex ; GO:0044545 | inferred from direct assay "CG4699, NSL1, nsl1, l(3)S009413, l(3)06536, E(nos), Nsl1, wah" "IPR029332:PEHE domain, IPR026180:KAT8 regulatory NSL complex subunit 1" CG4699 11-Aug-17 DroID_v2017_08 "Drer\kansl1b, Drer\kansl1l, Drer\kansl1a, Drer\LOC100333241" - Cele\mltn-11 Xtro\kansl1l "Mmus\Kansl1l, Mmus\Kansl1" "Hsap\KANSL1L, Hsap\KANSL1" DRSC15625 EK -0.878285485 1.420826987 -0.614001692 -7.10763892 -1.862795053 -0.120618708 FBgn0023537 CG17896 - http://flybase.org/reports/FBgn0023537 - protein_coding_gene methylmalonate-semialdehyde dehydrogenase (acylating) activity ; GO:0004491 | inferred from sequence or structural similarity with UniProtKB:Q02252 fatty-acyl-CoA binding ; GO:0000062 | inferred from sequence or structural similarity with UniProtKB:Q07536 methylmalonate-semialdehyde dehydrogenase (acylating) activity ; GO:0004491 | inferred from sequence or structural similarity with UniProtKB:Q02253 malonate-semialdehyde dehydrogenase (acetylating) activity ; GO:0018478 | inferred from sequence or structural similarity with UniProtKB:Q02253 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010061, InterPro:IPR015590, InterPro:IPR016160, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163 valine metabolic process ; GO:0006573 | inferred from sequence or structural similarity with UniProtKB:Q02252 thymine metabolic process ; GO:0019859 | inferred from sequence or structural similarity with UniProtKB:Q02253 valine metabolic process ; GO:0006573 | inferred from sequence or structural similarity with UniProtKB:Q02253 pyrimidine nucleobase metabolic process ; GO:0006206 | inferred from sequence or structural similarity with UniProtKB:Q02252" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q02252 "153323_at, EG:171D11.1, CG17896" "IPR010061:Methylmalonate-semialdehyde dehydrogenase, IPR015590:Aldehyde dehydrogenase domain, IPR016160:Aldehyde dehydrogenase, cysteine active site, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR034323:Methylmalonate semialdehyde dehydrogenase, mitochondrial" CG17896 11-Aug-17 DroID_v2017_08 Drer\aldh6a1 "Scer\ALD5, Scer\ALD2, Scer\ALD6" Cele\alh-8 Xtro\aldh6a1 Mmus\Aldh6a1 Hsap\ALDH6A1 viable DRSC18502 E 1.240730039 0.352853847 1.96410679 0.21719568 0.643696859 0.498358802 FBgn0267289 CR45725 - http://flybase.org/reports/FBgn0267289 non_protein_coding_gene - - - CR45725 - CR45725 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264787 CR44017 - http://flybase.org/reports/FBgn0264787 non_protein_coding_gene - - - CR44017 - CR44017 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062578 Mod(var)E1047 Mod(var)E1047 http://flybase.org/reports/FBgn0062578 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1047, Mod(var)E1047" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0266452 CTPsyn CTP synthase http://flybase.org/reports/FBgn0266452 protein_coding_gene CTP synthase activity ; GO:0003883 | inferred from sequence or structural similarity with HGNC:2519 CTP synthase activity ; GO:0003883 | inferred from sequence or structural similarity with UniProtKB:P17812 CTP biosynthetic process ; GO:0006241 | inferred from sequence or structural similarity with HGNC:2519 CTP biosynthetic process ; GO:0006241 | inferred from sequence or structural similarity with UniProtKB:P17812 neurogenesis ; GO:0022008 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cytoophidium ; GO:0097268 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG6854, CTPsyn, CG45070, CTPS" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR004468:CTP synthase, IPR017456:CTP synthase, N-terminal, IPR017926:Glutamine amidotransferase, IPR033828:CTP synthase GATase domain, IPR029062:Class I glutamine amidotransferase-like" CG45070 11-Aug-17 DroID_v2017_08 "Drer\ctps1a, Drer\ctps1b" "Scer\URA7, Scer\URA8" Cele\ctps-1 "Xtro\ctps1, Xtro\ctps2" "Mmus\Ctps, Mmus\Ctps2" "Hsap\CTPS2, Hsap\CTPS1" "lethal,recessive,small body,developmental rate defective,majority die during larval stage,neuroanatomy defective,viable" "cytoophidiumnos.UTR.THsimVP16,egg chamber,cytoophidiumAct.PU,follicle cell,cytoophidium | cell autonomous | somatic clonetub.PU,cell autonomous,somatic clone,cytoophidium | somatic clonetub.PU,cytoophidium | germline clone,germline clone,ganglion mother cell,embryonic/larval neuroblast" FBgn0010079 Rst(2)mth Resistance to malathion on chromosome 2 http://flybase.org/reports/FBgn0010079 - gene - - - Rst(2)mth - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260608 2L2938 - http://flybase.org/reports/FBgn0260608 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2938 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0266814 CR45276 - http://flybase.org/reports/FBgn0266814 non_protein_coding_gene - - - CR45276 - CR45276 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261269 conv convoluted http://flybase.org/reports/FBgn0261269 protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from electronic annotation with InterPro:IPR027176 "toll-like receptor 5 signaling pathway ; GO:0034146 | inferred from electronic annotation with InterPro:IPR027176 MyD88-dependent toll-like receptor signaling pathway ; GO:0002755 | inferred from electronic annotation with InterPro:IPR027176 positive regulation of cytokine production ; GO:0001819 | inferred from electronic annotation with InterPro:IPR027176 regulation of cytokine secretion ; GO:0050707 | inferred from electronic annotation with InterPro:IPR027176 defense response to bacterium ; GO:0042742 | inferred from electronic annotation with InterPro:IPR027176 motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR027176 "conv, CG8561, dALS, l(2)k06507b, Als, tartan/capricious-like, CT24963, ALS" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR026906:Leucine rich repeat 5, IPR027176:Toll-like receptor 5" CG8561 11-Aug-17 DroID_v2017_08 "Drer\tlr9, Drer\nyx, Drer\igfals, Drer\si:dkey-182i3.11" - Cele\lron-15 Xtro\nyx "Mmus\Tlr7, Mmus\Tlr3, Mmus\Tlr9, Mmus\Tlr5, Mmus\Tlr8, Mmus\Igfals, Mmus\Nyx" "Hsap\NYX, Hsap\IGFALS, Hsap\TLR5" FBgn0014147 dh double halteres http://flybase.org/reports/FBgn0014147 - gene - - - dh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027146 l(3)71DEa lethal (3) 71DEa http://flybase.org/reports/FBgn0027146 - gene - - - l(3)71DEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053653 Cadps Calcium-dependent secretion activator http://flybase.org/reports/FBgn0053653 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProtKB:Q62717 "dense core granule exocytosis ; GO:1990504 | inferred from electronic annotation with InterPro:IPR033227 synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement positive regulation of calcium ion-dependent exocytosis ; GO:0045956 | inferred from sequence or structural similarity with UniProtKB:Q62717 synaptic transmission, glutamatergic ; GO:0035249 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | non-traceable author statement synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity" synaptic vesicle ; GO:0008021 | non-traceable author statement synapse ; GO:0045202 | inferred from direct assay "dcaps, CG18026, dCAPS, l(4)102Fb, CG17881, CAPS, SDCAP, CG40477, CG33653, BcDNA:GH07283, Cadps, Caps, cap, caps" "IPR001849:Pleckstrin homology domain, IPR010439:Calcium-dependent secretion activator domain, IPR011993:PH domain-like, IPR014770:Munc13 homology 1, IPR033227:Calcium-dependent secretion activator" CG33653 11-Aug-17 DroID_v2017_08 "Drer\cadpsb, Drer\cadpsa, Drer\cadps2" - Cele\unc-31 "Xtro\cadps, Xtro\cadps2" "Mmus\Cadps2, Mmus\Unc13b, Mmus\Cadps, Mmus\Unc13a" "Hsap\UNC13A, Hsap\CADPS2, Hsap\CADPS" "viable,touch sensitivity defective,recessive,lethal,hypoactive,neurophysiology defective,locomotor behavior defective" "neuromuscular junction,synaptic vesicle" FBgn0003591 Su(var)2-9 Suppressor of variegation 2-9 http://flybase.org/reports/FBgn0003591 - gene - - - "Su-var(2)9, Su(var)2-9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,suppressor of variegation,dominant" FBgn0283467 Pol32 Pol32 polymerase delta subunit http://flybase.org/reports/FBgn0283467 protein_coding_gene DNA polymerase binding ; GO:0070182 | inferred from sequence model DNA repair ; GO:0006281 | inferred from mutant phenotype DNA synthesis involved in double-strand break repair via homologous recombination ; GO:0043150 | inferred from mutant phenotype - "pol32, CG3975, rd, BG:DS07295.3, BcDNA:GH08865, Pol32" - CG3975 11-Aug-17 DroID_v2017_08 Drer\pold3 - Cele\R04F11.3 - Mmus\Pold3 Hsap\POLD3 FBgn0023053 l(1)3Aj lethal (1) 3Aj http://flybase.org/reports/FBgn0023053 - gene - - - "A2/3, l(1)3Aj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051245 CG31245 - http://flybase.org/reports/FBgn0051245 protein_coding_gene - - - "CG3575, BcDNA:AT17586, CG31245" IPR006623:Testicular haploid expressed repeat CG31245 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0019781 l(1)27 lethal (1) 27 http://flybase.org/reports/FBgn0019781 - gene - - - l(1)27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033844 bbc bb in a boxcar http://flybase.org/reports/FBgn0033844 protein_coding_gene "phosphotransferase activity, for other substituted phosphate groups ; GO:0016780 | inferred from electronic annotation with InterPro:IPR000462" phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR000462 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000462 "Bbc, bbc, cept, CG6016, dCCS2" "IPR000462:CDP-alcohol phosphatidyltransferase, IPR014472:Choline/ethanolamine phosphotransferase" CG6016 11-Aug-17 DroID_v2017_08 "Drer\cept1a, Drer\cept1b, Drer\chpt1, Drer\si:ch211-197l9.4" "Scer\CPT1, Scer\EPT1" "Cele\cept-1, Cele\cept-2, Cele\F54D7.2" "Xtro\chpt1, Xtro\cept1, Xtro\ept1" "Mmus\Selenoi, Mmus\Chpt1, Mmus\Cept1" "Hsap\SELENOI, Hsap\CEPT1, Hsap\CHPT1" viable adult heart FBgn0028287 l(1)G0406 lethal (1) G0406 http://flybase.org/reports/FBgn0028287 gene - - - l(1)G0406 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025339 anon-58Fd anon-58Fd http://flybase.org/reports/FBgn0025339 - gene - - - "B2.1, anon-58Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037648 CG11975 - http://flybase.org/reports/FBgn0037648 protein_coding_gene - - - CG11975 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG11975 11-Aug-17 DroID_v2017_08 "Drer\wipi2, Drer\wdr45, Drer\wdr45b" "Scer\ATG18, Scer\HSV2" "Cele\atg-18, Cele\epg-6" "Xtro\wdr45, Xtro\wdr45b" "Mmus\Wipi1, Mmus\Wdr45b, Mmus\Wdr45, Mmus\Wipi2" "Hsap\WDR45, Hsap\WDR45B, Hsap\WIPI2, Hsap\WIPI1" "viable,fertile" FBgn0044034 Mod(rst)E188 Mod(rst)E188 http://flybase.org/reports/FBgn0044034 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E188, Mod(rst)E188" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0013278 Hsp70Bb Heat-shock-protein-70Bb http://flybase.org/reports/FBgn0013278 "FBgn0001232, FBgn0051359" protein_coding_gene - response to heat ; GO:0009408 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from mutant phenotype response to heat ; GO:0009408 | non-traceable author statement response to unfolded protein ; GO:0006986 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay "Hsp70, hsp70, HSP70, hsp70Bb, hsp70B, Hsp70Bc, Hsp70B, Hsp70Bbc, DMHSP7D1, Hsp 70, Hsp70A7d, dhsp70, Hsp70(87C), hsp-70, hsp70 87C, CG31359, Hsp70Bb, Hsp-70, dHsp70, Dm-hsp70, Bb, Hsp70bb" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG31359 11-Aug-17 DroID_v2017_08 "Drer\hsp70l, Drer\hspa8, Drer\hsp70.1, Drer\si:ch211-199o1.2, Drer\nckap1, Drer\hspa12b, Drer\hspa5, Drer\hspa13, Drer\hspa12a, Drer\hsp70.2, Drer\si:dkey-4p15.3, Drer\hsc70, Drer\hspa14" "Scer\SSQ1, Scer\SSB1, Scer\SSZ1, Scer\ECM10, Scer\SSA3, Scer\SSB2, Scer\SSA2, Scer\SSA1, Scer\KAR2, Scer\SSA4" "Cele\gex-3, Cele\hsp-3, Cele\F44E5.5, Cele\F44E5.4, Cele\F11F1.1, Cele\hsp-4, Cele\hsp-1, Cele\hsp-70" "Xtro\hspa14, Xtro\hspa1a, Xtro\hspa8, Xtro\hspa12b, Xtro\hspa13, Xtro\hspa2, Xtro\nckap1, Xtro\hspa1l, Xtro\nckap1l, Xtro\hspa1b, Xtro\hsp70, Xtro\hspa5" "Mmus\Hspa1l, Mmus\Hspa12a, Mmus\Hspa2, Mmus\Hspa8, Mmus\Hspa12b, Mmus\Hspa5, Mmus\Hspa1a, Mmus\Hspa14, Mmus\Hspa13, Mmus\Nckap1, Mmus\Nckap1l, Mmus\Hspa1b" "Hsap\HSPA12A, Hsap\HSPA1B, Hsap\HSPA1A, Hsap\HSPA12B, Hsap\HSPA1L, Hsap\HSPA2, Hsap\NCKAP1, Hsap\HSPA13, Hsap\HSPA5, Hsap\HSPA6, Hsap\NCKAP1L, Hsap\HSPA8, Hsap\HSPA14" "aging defective,male limited,heat sensitive" FBgn0034288 CG5084 - http://flybase.org/reports/FBgn0034288 protein_coding_gene - - - CG5084 IPR007931:Protein of unknown function DUF725 CG5084 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016935 smi65A smell impaired 65A http://flybase.org/reports/FBgn0016935 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi65A - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0015495 l(3)65ACe lethal (3) 65ACe http://flybase.org/reports/FBgn0015495 - gene - - - "V, l(3)65ACe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020768 1731\gag 1731 element gag http://flybase.org/reports/FBgn0020768 - transposable_element_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - "ORF1, 1731\gag" "IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041763 btd::Hsap\SP1 btd::Hsap\SP1 http://flybase.org/reports/FBgn0041763 engineered_fusion_gene - - - btd::Hsap\SP1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015494 l(3)65ACd lethal (3) 65ACd http://flybase.org/reports/FBgn0015494 - gene - - - "IV, l(3)65ACd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267571 CR45911 - http://flybase.org/reports/FBgn0267571 non_protein_coding_gene - - - "CR45911, pri-mir-13b-1_mir-13a_mir-2c" - CR45911 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052650 CG32650 - http://flybase.org/reports/FBgn0052650 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4410, CG32650" IPR031883:Protein of unknown function DUF4763 CG32650 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-36g24.3, Drer\adck3, Drer\adck4" Scer\COQ8 - "Xtro\adck3, Xtro\adck4" "Mmus\Coq8b, Mmus\Coq8a" "Hsap\COQ8B, Hsap\COQ8A" viable FBgn0266216 CR44911 - http://flybase.org/reports/FBgn0266216 non_protein_coding_gene - - - CR44911 - CR44911 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016046 noah noah http://flybase.org/reports/FBgn0016046 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available noah - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028305 l(1)G0377 lethal (1) G0377 http://flybase.org/reports/FBgn0028305 gene - - - l(1)G0377 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" brain FBgn0067754 l(1)G0096 lethal (1) G0096 http://flybase.org/reports/FBgn0067754 gene - - - l(1)G0096 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259404 C427 - http://flybase.org/reports/FBgn0259404 gene - - - C427 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing hair,wing,chaeta" FBgn0069246 bum boojum http://flybase.org/reports/FBgn0069246 gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bum - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,axon,dendrite,commissure" FBgn0035253 CG7971 - http://flybase.org/reports/FBgn0035253 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 RNA splicing ; GO:0008380 | inferred from sequence or structural similarity with protein_id:AAF21439" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "anon-EST:fe1A7, BcDNA:GH04236, CG7971" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR029360:Serine/arginine repetitive matrix protein, C-terminal, IPR013170:mRNA splicing factor Cwf21 domain" CG7971 11-Aug-17 DroID_v2017_08 Drer\srrm2 Scer\CWC21 Cele\rsr-2 "Xtro\srrm2, Xtro\nktr" "Mmus\Srrm2, Mmus\Dspp, Mmus\Srrm3" "Hsap\DSPP, Hsap\SRRM3, Hsap\SRRM2" FBgn0051759 CG31759 - http://flybase.org/reports/FBgn0051759 protein_coding_gene - - - "BcDNA:AT13596, ms(2)01284, BcDNA:LD05405, CG31759, 3635, d3635" IPR005135:Endonuclease/exonuclease/phosphatase CG31759 11-Aug-17 DroID_v2017_08 "Drer\pde12, Drer\cnot6a, Drer\cnot6b, Drer\cnot6l, Drer\nocta" "Scer\CCR4, Scer\NGL3, Scer\NGL1, Scer\NGL2" Cele\pde-12 "Xtro\noct, Xtro\cnot6l" "Mmus\Cnot6l, Mmus\Lrrc27, Mmus\Cnot6, Mmus\Noct, Mmus\Angel2, Mmus\Pde12" "Hsap\PDE12, Hsap\CNOT6, Hsap\CNOT6L, Hsap\NOCT, Hsap\ANGEL2" "male sterile,recessive,partially lethal - majority die,viable" FBgn0267926 CR46207 - http://flybase.org/reports/FBgn0267926 non_protein_coding_gene - - - "CR46207, lincRNA.912" - CR46207 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024668 l(2)k04207 lethal (2) k04207 http://flybase.org/reports/FBgn0024668 - gene - - - "42/7, l(2)k04207" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053664 CG33664 - http://flybase.org/reports/FBgn0053664 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33664 - CG33664 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265485 BG00357 - http://flybase.org/reports/FBgn0265485 gene - - - BG00357 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040885 CG14189 - http://flybase.org/reports/FBgn0040885 protein_coding_gene - - - CG14189 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027335 Rip11 Rab11 interacting protein http://flybase.org/reports/FBgn0027335 "FBgn0027272, FBgn0027314, FBgn0027318, FBgn0028271, FBgn0030942, FBgn0040180" protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab11 regulated exocytosis ; GO:0045055 | inferred from biological aspect of ancestor with PANTHER:PTN000405433 rhabdomere development ; GO:0042052 | inferred from mutant phenotype intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000405433 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000405433 "Rip11, l(1)G0297, CG6606, l(1)G0070, l(1)G0092, l(1)G0205, l(1)G0434, dRip11, l(1)G0003" "IPR000008:C2 domain, IPR019018:Rab-binding domain FIP-RBD" CG6606 11-Aug-17 DroID_v2017_08 "Drer\rab11fip1a, Drer\rab11fip1b, Drer\LOC570939, Drer\rab11fip5a, Drer\rab11fip2" - Cele\Y39F10B.1 "Xtro\rab11fip5, Xtro\rab11fip2, Xtro\rab11fip1" "Mmus\Rab11fip5, Mmus\Rab11fip1, Mmus\Rab11fip2" "Hsap\RAB11FIP2, Hsap\RAB11FIP5, Hsap\RAB11FIP1" "partially lethal - majority die,recessive,lethal,male,female,lethal - all die before end of P-stage,some die during pharate adult stage" "pupa,rhabdomere,somatic clone,actin cytoskeleton & eye photoreceptor cell | somatic clone,eye photoreceptor cell,rhabdomere | ectopic | somatic clone" FBgn0039529 CG5612 - http://flybase.org/reports/FBgn0039529 protein_coding_gene - - - CG5612 - CG5612 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0021839 l(2)k15206 lethal (2) k15206 http://flybase.org/reports/FBgn0021839 - gene - - - l(2)k15206 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036022 CG8329 - http://flybase.org/reports/FBgn0036022 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 sleep ; GO:0030431 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence model" - "SP170, CG8329" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG8329 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\zgc:112266" - - - "Mmus\Klk12, Mmus\C1s2, Mmus\Cela1, Mmus\C1s1" "Hsap\KLK7, Hsap\C1S, Hsap\PROC" FBgn0041838 Eth-AR205 Eth-AR205 http://flybase.org/reports/FBgn0041838 gene - - - "Eth[AR]205, Eth-AR205" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0000061 al aristaless http://flybase.org/reports/FBgn0000061 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay inferred from physical interaction with C15 "chaeta development ; GO:0022416 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from expression pattern leg disc development ; GO:0035218 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype elongation of arista core ; GO:0035015 | inferred from mutant phenotype" protein complex ; GO:0043234 | inferred from physical interaction with C15 "A1, CG3935, L13-4, AL, lambda13-4, al, Al" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR003654:OAR domain, IPR009057:Homeobox domain-like" CG3935 11-Aug-17 DroID_v2017_08 "Drer\pax7b, Drer\hhex, Drer\pax8, Drer\pax5, Drer\pax2b, Drer\arxb, Drer\arxa, Drer\pax9, Drer\pax1b, Drer\pax6a, Drer\rx3, Drer\pax7a, Drer\alx3, Drer\pax3a, Drer\sebox, Drer\alx1, Drer\pax10, Drer\pax2a, Drer\pax1a, Drer\pax6b" Scer\PHO2 "Cele\ceh-54, Cele\alr-1, Cele\pax-1, Cele\eyg-1, Cele\pax-2, Cele\vab-3, Cele\unc-4, Cele\egl-38, Cele\ceh-8" "Xtro\pax8, Xtro\pax6, Xtro\pax2, Xtro\pax1, Xtro\pax9, Xtro\arx, Xtro\pax5, Xtro\alx1, Xtro\pax3, Xtro\pax7" "Mmus\Arx, Mmus\Pax9, Mmus\Pax1, Mmus\Alx3, Mmus\Pax7, Mmus\Sebox, Mmus\Pax8, Mmus\Pax5, Mmus\Pax6, Mmus\Rax, Mmus\Pax4, Mmus\Alx1, Mmus\Pax3, Mmus\Pax2" "Hsap\PAX7, Hsap\ARX, Hsap\ALX4, Hsap\PAX2, Hsap\PAX8, Hsap\PAX5, Hsap\SEBOX, Hsap\PAX3, Hsap\PAX4, Hsap\PAX9, Hsap\PAX1, Hsap\PAX6, Hsap\ALX1, Hsap\ALX3" " larval stage | third instar , embryonic stage | stage >=10 , embryonic stage | stage >=11 , embryonic stage | stage 13 " " ventral thoracic disc | restricted

, embryonic maxillary segment | restricted

, embryonic antennal segment | restricted

, embryonic mandibular segment | restricted

, embryonic labial segment | restricted

, embryonic prothoracic segment | restricted

, embryonic metathoracic segment | restricted

, mesothoracic segment | restricted

, embryonic abdominal segment 1--8

, eye-antennal disc | restricted

, dorsal mesothoracic disc | restricted

" "viable,fertile,wild-type,lethal,recessive,visible,poor,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,mating defective,female,lethal - all die before end of P-stage,some die during pharate adult stage,female sterile,partially lethal - majority die" "wing,ectopic,arista,posterior scutellar bristle,scutellum,sternopleural bristle,unguis,leg,distal,mesothoracic bristle,wing vein L2,somatic clone,pleurum,tarsal segment 4,pretarsus,wing vein L1,thorax,wing vein,eye,adult thorax,macrochaeta & thorax,microchaeta & thorax,wing vein L3,tarsal segment" FBgn0263709 CR43661 - http://flybase.org/reports/FBgn0263709 non_protein_coding_gene - - - CR43661 - CR43661 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003657 swy swarthy http://flybase.org/reports/FBgn0003657 - gene - - - swy - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male fertile,female fertile,fertile,viable,reduced,eye color defective,body color defective" "eye,scutellum,pigment cell" FBgn0001366 l(1)1Fe lethal (1) 1Fe http://flybase.org/reports/FBgn0001366 - gene - - - l(1)1Fe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027346 fs(2)58g fs(2)58g http://flybase.org/reports/FBgn0027346 FBgn0000962 gene - - - "fs(2)[58g], fs(2)58g" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile,recessive,male fertile" egg FBgn0003688 tft tufts http://flybase.org/reports/FBgn0003688 - gene - - - tft - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,cold sensitive" FBgn0002373 l(3)91Fe lethal (3) 91Fe http://flybase.org/reports/FBgn0002373 FBgn0002377 gene - - - "l(DIX43)c, C5, l(3)C4-9, l(3)C4-7, l(3)C4-4, l(3)C4-18, l(3)BE81, l(3)BE80, l(3)92Ac, l(3)91Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061058 l(3)S022527 lethal (3) S022527 http://flybase.org/reports/FBgn0061058 gene - - - "0225/27, l(3)S022527" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086022 snoRNA:Me28S-U1130 - http://flybase.org/reports/FBgn0086022 snoRNA_gene - - - "snoRNA:Me28S-U1130, Me28S-Um1130, CR34651" - CR34651 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260289 GSd017 - http://flybase.org/reports/FBgn0260289 gene - - - GSd017 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020361 anon-1D2 anon-1D2 http://flybase.org/reports/FBgn0020361 - gene - - - "1D2, anon-1D2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052354 CG32354 - http://flybase.org/reports/FBgn0052354 protein_coding_gene - - - "CG17355, CK01670, BEST:CK01670, CG7159, CG7027, CG32354" IPR002350:Kazal domain CG32354 11-Aug-17 DroID_v2017_08 "Drer\fstl1a, Drer\agrn, Drer\fsta, Drer\fstl1b" - "Cele\ZK813.6, Cele\agr-1, Cele\F29G6.1" "Xtro\fstl1, Xtro\fst" "Mmus\Tmeff2, Mmus\Tmeff1, Mmus\Fst, Mmus\Spink6, Mmus\Spink5, Mmus\Agrn, Mmus\Spink12, Mmus\Fstl1" "Hsap\FST, Hsap\SPINK6, Hsap\AGRN, Hsap\MSANTD3-TMEFF1, Hsap\FSTL1, Hsap\SPINK5, Hsap\TMEFF2" viable FBgn0002216 l(3)67BDn lethal (3) 67BDn http://flybase.org/reports/FBgn0002216 - gene - - - l(3)67BDn - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262423 mir-281-2 mir-281-2 stem loop http://flybase.org/reports/FBgn0262423 miRNA_gene - - - "mir-281, 281-2, mir-281-2, miR-281-2, MIR-281, CR42975, CR33596, miR-281b, mir-281b, miR-281, CR33593, dme-mir-281-2, CR33597, mir-281-2*, miR-281bS, mir-281bS, miR-281-2-star, dme-miR-281, dme-miR-281-2-5p, dme-miR-281-2" - CR42975 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" wing margin FBgn0044417 Scim10 Sensitized chromosome inheritance modifier 10 http://flybase.org/reports/FBgn0044417 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0040755 CG17580 - http://flybase.org/reports/FBgn0040755 protein_coding_gene - - - "BcDNA:AT18054, CG17580" - CG17580 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069984 BG02257 BG02257 http://flybase.org/reports/FBgn0069984 gene - - - BG02257 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,long lived,female,male,heat stress response defective,starvation stress response defective" FBgn0265842 CR44631 - http://flybase.org/reports/FBgn0265842 non_protein_coding_gene - - - CR44631 - CR44631 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063404 l(3)CG3 lethal (3) CG3 http://flybase.org/reports/FBgn0063404 gene - - - l(3)CG3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053179 beat-IIIb beat-IIIb http://flybase.org/reports/FBgn0053179 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic - "beat IIIb, CG4855, CG15135, CG33179, beat-IIIb, Beat-IIIb" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG33179 11-Aug-17 DroID_v2017_08 "Drer\jam2b, Drer\f11r.2, Drer\zgc:172106" - - Xtro\f11r - Hsap\CADM2 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038536 CG7655 - http://flybase.org/reports/FBgn0038536 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype nuclear envelope ; GO:0005635 | inferred from sequence or structural similarity with UniProtKB:Q8IXM6 CG7655 IPR033580:Nurim-like CG7655 11-Aug-17 DroID_v2017_08 Drer\nrm - - Xtro\nrm Mmus\Nrm "Hsap\NRM, Hsap\ICMT" "viable,visible" chaeta FBgn0027280 l(1)G0193 lethal (1) G0193 http://flybase.org/reports/FBgn0027280 "FBgn0029064, FBgn0029984" protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "l(1)G0327, CG2206, l(1)G0193" IPR032062:Protein of unknown function DUF4803 CG2206 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable" FBgn0266130 144Y - http://flybase.org/reports/FBgn0266130 gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - 144Y - - 11-Aug-17 DroID_v2017_08 - - - - - - gravitaxis defective FBgn0067374 l(2)NC133 lethal (2) NC133 http://flybase.org/reports/FBgn0067374 gene - - - "NC133, l(2)NC133" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259646 B1520 - http://flybase.org/reports/FBgn0259646 gene - - - B1520 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0030085 CG6999 - http://flybase.org/reports/FBgn0030085 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000472 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 small-subunit processome assembly ; GO:0034462 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000480 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 nucleus ; GO:0005634 | inferred by curator from GO:0000381 CG6999 "IPR000504:RNA recognition motif domain, IPR034353:ABT1/ESF2, RNA recognition motif" CG6999 11-Aug-17 DroID_v2017_08 Drer\abt1 Scer\ESF2 Cele\F57B10.8 Xtro\abt1 Mmus\Abt1 Hsap\ABT1 FBgn0003496 square square http://flybase.org/reports/FBgn0003496 - gene - - - "sq, square" - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0003392 shi shibire http://flybase.org/reports/FBgn0003392 "FBgn0030705, FBgn0045942, FBgn0045943, FBgn0045944" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000375, InterPro:IPR001401, InterPro:IPR003130, InterPro:IPR030381 GTPase activity ; GO:0003924 | non-traceable author statement microtubule binding ; GO:0008017 | inferred from direct assay actin binding ; GO:0003779 | inferred from direct assay GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000170013" "memory=0007613 |...<> synaptic vesicle recycling=0036465 |...<> positive regulation of actin filament polymerization=0030838 |...<> epithelium development=0060429 |...<> chemical synaptic transmission=0007268 |...<> vesicle-mediated transport=0016192 | traceable author statement <> clathrin-dependent endocytosis=0072583 |...<> negative regulation of protein phosphorylation=0001933 |...<> synaptic vesicle endocytosis=0048488 | traceable author statement <> memory=0007613 | traceable author statement <> cortical actin cytoskeleton organization=0030866 |...<> endocytosis=0006897 |...<> receptor-mediated endocytosis=0006898 | <> protein localization to plasma membrane=0072659 |...<> synaptic vesicle transport=0048489 |... direct assay <> synaptic vesicle budding from presynaptic endocytic zone membrane=0016185 | traceable author statement <> germarium-derived egg chamber formation=0007293 |...<> mitotic cytokinesis=0000281 |...<> regulation of actin filament-based process=0032970 |... genetic interaction with jar <> regulation of synapse structure or activity=0050803 |...<> epithelial cell migration, open tracheal system=0007427 |...<> regulation of short-term neuronal synaptic plasticity=0048172 |...<> positive regulation of Notch signaling pathway=0045747 |...<> regulation of growth=0040008 |...<> mitochondrial fission=0000266 |... biological aspect of ancestor with PANTHER:PTN000902162 <> sperm individualization=0007291 |...<> dynamin family protein polymerization involved in mitochondrial fission=0003374 |... biological aspect of ancestor with PANTHER:PTN000170085 <> synaptic vesicle budding from presynaptic endocytic zone membrane=0016185 |...<> mitotic actomyosin contractile ring assembly=1903475 |...<> regulation of actin cytoskeleton organization=0032956 |... genetic interaction with jar <> endocytosis=0006897 | traceable author statement <> learning=0007612 |...<> open tracheal system development=0007424 |...<> membrane fusion=0061025 |... biological aspect of ancestor with PANTHER:PTN000170085 <> conditioned taste aversion=0001661 |...<> cellularization=0007349 |...<> sperm individualization=0007291 |... genetic interaction with jar <> endocytosis=0006897 |... direct assay <> compound eye retinal cell programmed cell death=0046667 |...<> cellularization=0007349 | traceable author statement <> synaptic vesicle endocytosis=0048488 |...<> extracellular matrix organization=0030198 |...<> short-term memory=0007614 |...<> membrane fission=0090148 |...<> dorsal appendage formation=0046843 |...<> regulation of tube architecture, open tracheal system=0035152 |...<> olfactory learning=0008355 |... direct assay <> border follicle cell migration=0007298 |...<> ovarian follicle cell development=0030707 |...<> syncytial blastoderm mitotic cell cycle=0035186 |...<> larval feeding behavior=0030536 |...<> response to heat=0009408 |...<> morphogenesis of a polarized epithelium=0001738 |...<> proboscis extension reflex=0007637 |...<> synaptic vesicle membrane organization=0048499 |...<> synaptic vesicle endocytosis=0048488 |... direct assay <> salivary gland morphogenesis=0007435 |...<> adherens junction maintenance=0034334 |... mutant phenotype" microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR027188 mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay sperm individualization complex ; GO:0070864 | inferred from direct assay synapse ; GO:0045202 | inferred from mutant phenotype mitotic spindle ; GO:0072686 | inferred from direct assay presynaptic active zone membrane ; GO:0048787 | "shi, Dyn, Shi, CG18102, Ddyn4, Ddyn3, Ddyn, l(1)shi, l(1)VII, anon-WO0153538.14, anon-WO0153538.13, anon-WO0153538.12, DYN, dyn, dDyn, shibire, shibere, DNM3, dynamin, Shibire" "IPR000375:Dynamin central domain, IPR001401:Dynamin, GTPase domain, IPR001849:Pleckstrin homology domain, IPR003130:Dynamin GTPase effector, IPR011993:PH domain-like, IPR030381:Dynamin-type guanine nucleotide-binding (G) domain, IPR019762:Dynamin, GTPase region, conserved site, IPR020850:GTPase effector domain, IPR027188:Dynamin-2, IPR027741:Dynamin-1, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022812:Dynamin superfamily" CG18102 11-Aug-17 DroID_v2017_08 "Drer\dnm1l, Drer\dnm1b, Drer\si:dkeyp-110c12.3, Drer\mxf, Drer\dnm2b, Drer\mxg, Drer\dnm2a, Drer\dnm1a, Drer\mxd, Drer\mxe, Drer\mxc, Drer\mxb, Drer\dnm3a, Drer\si:dkey-32e23.4" "Scer\VPS1, Scer\DNM1, Scer\MGM1" "Cele\drp-1, Cele\dyn-1" "Xtro\dnm2, Xtro\dnm1l, Xtro\dnm3, Xtro\dnm1" "Mmus\Dnm3, Mmus\Dnm1, Mmus\Dnm1l, Mmus\Dnm2" "Hsap\DNM1, Hsap\DNM2, Hsap\DNM1L, Hsap\DNM3, Hsap\MX1, Hsap\MX2" " larval stage , embryonic stage | late , adult stage && oogenesis stage , adult stage , spermatogenesis && adult stage , adult stage | male , embryonic stage | early , embryonic stage " " central nervous system

, ovary

, peripheral nervous system

, sense organ

, supraesophageal ganglion

, thoracico-abdominal ganglion

, subesophageal ganglion

, spermatogonium

, ventral nerve cord

, optic lobe

, adult head

, imaginal disc

, testis

, oocyte

, nurse cell

, antenno-maxillary complex

, spermatocyte

, male accessory gland

, retina

, adult brain

" "paralytic,heat sensitive,developmental rate defective,visible,somatic clone,phototaxis defective,locomotor behavior defective,smell perception defective,neuroanatomy defective,lethal,some die during immature adult stage,recessive,locomotor rhythm defective,neoplasia,neurophysiology defective,heat stress response defective,visual behavior defective,temperature conditional,endocytosis defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,uncoordinated,dominant,chemical resistant,feeding behavior defective,courtship behavior defective,song defective,mating defective,hypoactive,learning defective,memory defective,behavior defective,taste perception defective,male,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,gravitaxis defective,optomotor response defective,circadian behavior defective,increased cell death,mating behavior defective,flight defective,chemical sensitive,touch sensitivity defective,touch perception defective,proboscis extension reflex defective,thermotaxis behavior defective,cell growth defective,increased cell size" "eye,somatic clone,eye disc,wing hair,supernumerary,heat sensitive,ensheathing neuropil associated glial cell,glial cell,synapse,embryonic ventral epidermis,embryonic epidermis,photoreceptor cell & synaptic vesicle,embryo,apical plasma membrane | heat sensitive,coated pit,synaptic vesicle | heat sensitive,synapse | heat sensitive,oocyte,endosome,retina,garland cell & endosome,mesothoracic tarsal bristle,presumptive embryonic/larval tracheal system,synaptic vesicle,somatic muscle,epidermis,microchaeta,syncytial blastoderm embryo,endosome | heat sensitive,mesothoracic metatarsus,primary pigment cell,secondary pigment cell,ectopic,wing vein L3,wing vein L4,wing vein L5,NMJ bouton,actin filament & spermatid | conditional ts,wing cell,adherens junction & wing cell | pupal stage | conditional - heat sensitive,mouthpart,rhabdomere,eye photoreceptor cell,dorsal trunk primordium,neuromuscular junction | heat sensitive,metatarsus,embryonic/larval neuromuscular junction,rhabdomere | heat sensitive,bouton,synapse | temperature conditional,embryonic/larval tracheal system,temperature conditional,embryonic/larval dorsal trunk,ommatidium,eye photoreceptor cell & ommatidium | ectopic,sensory mother cell,neuron,mesothoracic tergum & macrochaeta,wing & macrochaeta,macrochaeta,sensillum trichodeum of antennal segment 3,sensillum basiconicum of antennal segment 3,sensillum coeloconicum of antennal segment 3,trichogen cell,tormogen cell,macrochaeta & thorax | conditional ts,microchaeta & thorax | conditional ts,dorsal row,ventral row,abdominal 2 ventral longitudinal muscle & larval somatic muscle | conditional ts,larval somatic muscle & presynaptic membrane | conditional ts,larval somatic muscle & synaptic vesicle | conditional ts,presumptive embryonic salivary gland,photoreceptor cell,optic cartridge,wing,adult mushroom body,adult brain,neuromuscular junction | heat sensitiveMhc.PW,brain,glial cell & brain & pupa | conditional tsrepo,mushroom body,mushroom body vertical lobe,dorsal multidendritic neuron ddaC,adult fat body,giant fiber neuron,mushroom body dorsal paired medial cell,mesothoracic extracoxal depressor muscle 66,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,medulla,lamina,axon & eye photoreceptor cell | conditional - heat sensitiveGMR.PF,dendrite | third instar larval stageGMR.PF,LNv neuron | third instar larval stage,dorsal appendage,dendritic arborizing neuron,dendrite | larval stage | heat sensitive109(2)80,class IV dendritic arborizing neuron,tertiary pigment cell,embryonic/larval glial cell,CSD interneuron,reticular neuropil associated glial cell,gamma Kenyon cell,synapsealrm.PD,multidendritic neuron,type II bouton,proboscis,air sac primordium,dorsal multidendritic neuron ddaC | pupal stage,border follicle cell,polar follicle cell,denticle belt,embryonic/first instar larval cuticle,denticle row 1,denticle row 2,denticle row 3,cuticle,ventral nerve cord commissure,abdominal ventral acute muscle 1 founder cell,abdominal ventral acute muscle 2 founder cell,abdominal ventral acute muscle 3 founder cell,wing disc,wing margin,wing margin bristle,fat body,imaginal disc,embryonic/larval neuroblast,embryonic myoblast,macrophage,embryonic/larval midgut | third instar larval stage,epithelium,female germline cyst" DRSC20373 EK 0.2744575 -1.427375881 1.648111937 -0.951967983 -1.245049712 -1.576499953 FBgn0085523 Su(Ste):CR40820 - http://flybase.org/reports/FBgn0085523 non_protein_coding_gene - - - "CG40820, Su(Ste):CR40820, CR40820" - CR40820 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034834 LS2 Large Subunit 2 http://flybase.org/reports/FBgn0034834 protein_coding_gene poly-pyrimidine tract binding ; GO:0008187 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 pre-mRNA 3'-splice site binding ; GO:0030628 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 protein binding ; GO:0005515 | inferred from physical interaction with U2af38 RNA binding ; GO:0003723 | inferred from mutant phenotype mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR006529 negative regulation of RNA splicing ; GO:0033119 | inferred from mutant phenotype regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype nuclear speck ; GO:0016607 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 commitment complex ; GO:0000243 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 U2AF ; GO:0089701 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 "cg3162, CG3162, LS2" "IPR000504:RNA recognition motif domain, IPR006529:U2 snRNP auxilliary factor, large subunit, splicing factor, IPR003954:RNA recognition motif domain, eukaryote" CG3162 11-Aug-17 DroID_v2017_08 "Drer\uhmk1, Drer\u2af2a, Drer\u2af2b" "Scer\RNA15, Scer\MUD2" "Cele\uaf-1, Cele\Y82E9BR.2" Xtro\u2af2 "Mmus\U2af2, Mmus\Uhmk1" "Hsap\PPIE, Hsap\U2AF2, Hsap\UHMK1" "viable,lethal" DRSC04340 I -0.900722331 -1.838062114 -0.713948267 -0.004026071 0.348151905 -0.58474161 FBgn0030015 CG10761 - http://flybase.org/reports/FBgn0030015 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:26025 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:26025 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with HGNC:26025 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with HGNC:26025 CG10761 "IPR011016:Zinc finger, RING-CH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033275:E3 ubiquitin-protein ligase MARCH-like" CG10761 11-Aug-17 DroID_v2017_08 "Drer\march6, Drer\march5l, Drer\march8, Drer\march5" Scer\SSM4 "Cele\marc-5, Cele\M110.3, Cele\marc-1, Cele\marc-6" "Xtro\march5, Xtro\march8" "Mmus\March5, Mmus\March1, Mmus\March8, Mmus\March10, Mmus\March6" "Hsap\MARCH8, Hsap\MARCH10, Hsap\MARCH6, Hsap\MARCH1, Hsap\MARCH5, Hsap\MARCH7" viable DRSC27665 K 0.045501567 0.431620401 0.162969916 0.612334621 0.171803971 1.882791523 FBgn0065162 l(3)SH040 lethal (3) SH040 http://flybase.org/reports/FBgn0065162 gene - - - "l(3)SH040, l(2)SH3 040" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264877 CR44068 - http://flybase.org/reports/FBgn0264877 non_protein_coding_gene - - - CR44068 - CR44068 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041729 p400 p400 http://flybase.org/reports/FBgn0041729 gene protein binding ; GO:0005515 | inferred from physical interaction with z - brahma complex ; GO:0035060 | colocalizes_with inferred from direct assay p400 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069216 gl(3R)70-22 gl(3R)70-22 http://flybase.org/reports/FBgn0069216 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(3R)70-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect,cephalopharyngeal skeleton" FBgn0005205 l(3)DTS9 lethal (3) DTS9 http://flybase.org/reports/FBgn0005205 - gene - - - "DTS-9, l(3)DTS9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,female sterile" FBgn0040344 CG3711 - http://flybase.org/reports/FBgn0040344 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "EG:BACR7A4.19, CG3711" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011333:SKP1/BTB/POZ domain, IPR015915:Kelch-type beta propeller" CG3711 11-Aug-17 DroID_v2017_08 "Drer\hcfc1a, Drer\klhdc4, Drer\lztr1, Drer\hcfc1b, Drer\rabepk" "Scer\KEL1, Scer\KEL2, Scer\KEL3" "Cele\F53E4.1, Cele\herc-1, Cele\Y50D7A.1, Cele\hcf-1" Xtro\lztr1 "Mmus\Rabepk, Mmus\Hcfc2, Mmus\Klhdc3, Mmus\Hcfc1, Mmus\Fbxo42, Mmus\Lztr1, Mmus\Klhdc9, Mmus\Klhdc4" "Hsap\KLHDC3, Hsap\LZTR1, Hsap\RABEPK, Hsap\KLHDC4, Hsap\HCFC2, Hsap\FBXO42, Hsap\KLHDC9, Hsap\HCFC1" viable DRSC26706 EK 0.897802722 0.651957744 1.770357193 0.076673707 0.492580824 1.514460153 FBgn0005105 gusD gustatory D http://flybase.org/reports/FBgn0005105 - gene molecular_function ; GO:0003674 | no biological data available larval feeding behavior ; GO:0030536 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gusD - - 11-Aug-17 DroID_v2017_08 - - - - - - taste perception defective FBgn0060951 l(3)S036909 lethal (3) S036909 http://flybase.org/reports/FBgn0060951 gene - - - "369/9, 0369/09, l(3)S036909" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0263936 BG00004 - http://flybase.org/reports/FBgn0263936 gene - - - BG00004 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,female limited,temperature response defective,gravitaxis defective" FBgn0037203 slif slimfast http://flybase.org/reports/FBgn0037203 protein_coding_gene basic amino acid transmembrane transporter activity ; GO:0015174 | inferred from direct assay amino acid transmembrane transport ; GO:0003333 | inferred from electronic annotation with InterPro:IPR002293 amino acid transport ; GO:0006865 | inferred from direct assay growth ; GO:0040007 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype lipid metabolic process ; GO:0006629 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002293 "Slif, CG11128, slif, slifA, slimfast" "IPR002293:Amino acid/polyamine transporter I, IPR029485:Cationic amino acid transporter, C-terminal" CG11128 11-Aug-17 DroID_v2017_08 "Drer\slc7a14a, Drer\slc7a1, Drer\slc7a3b, Drer\slc7a3a, Drer\slc7a14b, Drer\slc7a4, Drer\zgc:175280, Drer\zgc:63694, Drer\slc7a2" "Scer\MMP1, Scer\SAM3, Scer\CAN1, Scer\ALP1, Scer\AGP1, Scer\AGP2, Scer\HIP1, Scer\BAP3, Scer\AGP3, Scer\TAT2, Scer\SSY1, Scer\LYP1, Scer\UGA4, Scer\BAP2, Scer\DIP5, Scer\PUT4, Scer\GAP1, Scer\GNP1, Scer\TAT1" "Cele\F23F1.6, Cele\aat-5, Cele\B0454.6, Cele\Y53F4B.12, Cele\C50D2.2" "Xtro\slc7a4, Xtro\slc7a2.2, Xtro\slc7a1, Xtro\slc7a14, Xtro\slc7a2.1, Xtro\slc7a3" "Mmus\Slc7a4, Mmus\Slc7a14, Mmus\Slc7a1, Mmus\AU018091, Mmus\Slc7a3, Mmus\Slc7a2" "Hsap\SLC7A3, Hsap\SLC7A2, Hsap\SLC7A4, Hsap\SLC7A1, Hsap\SLC7A14" larval stage organism | ubiquitous "viable,fertile,decreased cell number,decreased cell size,lethal - all die before end of larval stage,partially,some die during larval stage,developmental rate defective,lethal,visible,increased cell number" "wing,posterior compartment,embryonic/larval fat body,larva,lipid droplet & larval oenocyteppl.PP,lipid droplet & larval fat bodyppl.PP,lipid droplet & larval oenocyteLsp2.PH,embryonic/larval neuroblast" FBgn0031580 CG15423 - http://flybase.org/reports/FBgn0031580 protein_coding_gene - - - CG15423 - CG15423 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0083253 E(smoDN)E Enhancer of smoDN group E http://flybase.org/reports/FBgn0083253 gene - smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "Group E, E(smoDN)E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024930 Su(var)2-b204 Su(var)2-b204 http://flybase.org/reports/FBgn0024930 - gene - - - "Su-var(2)b204, Su(var)2-b204" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041738 l(2)k17019a lethal (2) k17019a http://flybase.org/reports/FBgn0041738 gene - - - l(2)k17019a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031239 CG17075 - http://flybase.org/reports/FBgn0031239 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG17075 "IPR001594:Palmitoyltransferase, DHHC domain" CG17075 11-Aug-17 DroID_v2017_08 "Drer\zdhhc7, Drer\LOC100334198, Drer\zdhhc23b, Drer\zdhhc1, Drer\zdhhc24, Drer\zgc:77880, Drer\zdhhc9, Drer\zdhhc21, Drer\zdhhc12a, Drer\zdhhc5b, Drer\zdhhc3a, Drer\zdhhc22, Drer\zdhhc18a, Drer\zdhhc8b, Drer\zdhhc3b, Drer\zdhhc4, Drer\zdhhc12b, Drer\zdhhc14, Drer\zdhhc5a, Drer\zdhhc23a" "Scer\PFA5, Scer\ERF2, Scer\PFA4, Scer\SWF1" "Cele\dhhc-11, Cele\dhhc-8" "Xtro\zdhhc14, Xtro\zdhhc8, Xtro\zdhhc24, Xtro\zdhhc7, Xtro\zdhhc1, Xtro\zdhhc21, Xtro\zdhhc3, Xtro\zdhhc9, Xtro\zdhhc12, Xtro\dnz1" "Mmus\Zdhhc14, Mmus\Zdhhc4, Mmus\Zdhhc1, Mmus\Zdhhc12, Mmus\Zdhhc19, Mmus\Zdhhc22, Mmus\Zdhhc3, Mmus\Zdhhc24, Mmus\Zdhhc5, Mmus\Zdhhc21, Mmus\Zdhhc7, Mmus\Zdhhc8, Mmus\Zdhhc11, Mmus\Zdhhc23, Mmus\Zdhhc9, Mmus\Zdhhc18, Mmus\Zdhhc25" "Hsap\ZDHHC4, Hsap\ZDHHC18, Hsap\ZDHHC23, Hsap\ZDHHC11, Hsap\ZDHHC12, Hsap\ZDHHC21, Hsap\ZDHHC9, Hsap\ZDHHC24, Hsap\ZDHHC14, Hsap\ZDHHC8, Hsap\ZDHHC19, Hsap\ZDHHC7, Hsap\ZDHHC11B, Hsap\ZDHHC5, Hsap\ZDHHC22, Hsap\ZDHHC1, Hsap\ZDHHC3" viable DRSC00483 K -0.385386609 0.561626818 -0.131428872 -0.028656741 1.940463566 2.198337619 FBgn0263875 PL26 - http://flybase.org/reports/FBgn0263875 gene - - - PL26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval neuroblast,embryonic/larval brain" FBgn0015424 l(1)1CDa lethal (1) 1CDa http://flybase.org/reports/FBgn0015424 - gene - - - l(1)1CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083034 snoRNA:Psi18S-525e snoRNA:Psi18S-525e http://flybase.org/reports/FBgn0083034 snoRNA_gene - - - "snoRNA:Psi18S-525e, psi18S-525e, CR34577" - CR34577 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050495 CG30495 - http://flybase.org/reports/FBgn0050495 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - - "CG17986, CG30495" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG30495 11-Aug-17 DroID_v2017_08 "Drer\dhrs13a.2, Drer\dhrs13a.1, Drer\si:ch211-107o10.3, Drer\si:ch211-165b10.3, Drer\si:dkey-73n8.3, Drer\dhrsx, Drer\rdh14b, Drer\zgc:112332, Drer\rdh12, Drer\dhrs13l1, Drer\dhrs13a.3, Drer\zgc:153441, Drer\si:dkey-174n20.1, Drer\rdh12l, Drer\rdh14a, Drer\flj13639, Drer\dhrs12, Drer\ascc1, Drer\cbr1, Drer\cbr1l, Drer\si:dkey-23o4.6, Drer\si:dkey-94e7.2, Drer\zgc:64106" "Scer\GPI11, Scer\YNL181W, Scer\YKL107W, Scer\ENV9" "Cele\C27D8.4, Cele\dhs-22" "Xtro\rdh14, Xtro\dhrsx, Xtro\dhrs13, Xtro\rdh11, Xtro\dhrs12, Xtro\rdh13, Xtro\ascc1" "Mmus\Dhrsx, Mmus\1700003E16Rik, Mmus\Rdh12, Mmus\Cbr1, Mmus\Wwox, Mmus\Rdh13, Mmus\Rdh11, Mmus\Ascc1, Mmus\Cbr3, Mmus\Dhrs13, Mmus\Rdh14" "Hsap\RDH13, Hsap\C2orf81, Hsap\OSTC, Hsap\CBR3, Hsap\RDH14, Hsap\DHRS12, Hsap\DHRS13, Hsap\RDH12, Hsap\CBR1, Hsap\DHRSX, Hsap\RDH11" viable FBgn0037098 Wnk Wnk kinase http://flybase.org/reports/FBgn0037098 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR024678 protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR024678 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein kinase activity ; GO:0004672 | inferred from direct assay" axon guidance ; GO:0007411 | inferred from mutant phenotype positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype inferred from genetic interaction with dsh inferred from genetic interaction with fz2 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with fz inferred from genetic interaction with fz2 wing disc development ; GO:0035220 | inferred from mutant phenotype positive regulation of potassium ion import ; GO:1903288 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | NOT inferred from key residues protein autophosphorylation ; GO:0046777 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:14540 "WNK, wnk, CG7177, cg7177, Wnk, DWNK, dWNK" "IPR011009:Protein kinase-like domain, IPR008271:Serine/threonine-protein kinase, active site, IPR000719:Protein kinase domain, IPR024678:Serine/threonine-protein kinase OSR1/WNK, CCT domain" CG7177 11-Aug-17 DroID_v2017_08 "Drer\wnk4b, Drer\prkca, Drer\wnk2, Drer\wnk4a, Drer\wnk1a, Drer\wnk1b" - Cele\wnk-1 "Xtro\wnk3, Xtro\wnk1, Xtro\wnk4" "Mmus\Wnk3, Mmus\Wnk4, Mmus\Wnk2, Mmus\Wnk1" "Hsap\WNK1, Hsap\WNK3, Hsap\WNK2, Hsap\WNK4, Hsap\MAST2" "lethal,recessive,visible,somatic clone,neuroanatomy defective,viable,size defective" "wing vein,ectopic,somatic clone,microchaeta,macrochaeta,abdominal segment,wing margin,abdominal segment | pharate adult stage,embryonic/larval peripheral nervous system,trichogen cell,posterior wing margin,wing margin bristle,wing,posterior,wing vein L4" DRSC23372 IK -1.564982365 -1.893217094 -0.761355005 -0.650185289 -1.69331069 -0.940173761 FBgn0050502 fa2h fatty acid 2-hydroylase http://flybase.org/reports/FBgn0050502 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006694 fatty acid alpha-hydroxylase activity ; GO:0080132 | inferred from biological aspect of ancestor with PANTHER:PTN000304948 fatty acid in-chain hydroxylase activity ; GO:0052722 | inferred from direct assay lipid biosynthetic process ; GO:0008610 | inferred from electronic annotation with InterPro:IPR006694 fatty acid metabolic process ; GO:0006631 | inferred from biological aspect of ancestor with PANTHER:PTN000304948 oxidation-reduction process ; GO:0055114 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR014430 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000304948 "CG1645, CG1642, CG30502, fa2h, FA2H" "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR006694:Fatty acid hydroxylase, IPR018506:Cytochrome b5, heme-binding site, IPR014430:Sterol desaturase Scs7" CG30502 11-Aug-17 DroID_v2017_08 "Drer\cyb5a, Drer\fa2h" "Scer\SCS7, Scer\CYB5" "Cele\cytb-5.1, Cele\cytb-5.2, Cele\D2023.1, Cele\C25A1.5" Xtro\fa2h "Mmus\Cyb5a, Mmus\Fa2h, Mmus\Cyb5b" "Hsap\CYB5B, Hsap\FA2H, Hsap\CYB5A" "short lived,viable,fertile" FBgn0058347 CG40347 - http://flybase.org/reports/FBgn0058347 protein_coding_gene - - - CG40347 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027298 l(1)G0137 lethal (1) G0137 http://flybase.org/reports/FBgn0027298 - gene - - - l(1)G0137 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0042207 CG18530 - http://flybase.org/reports/FBgn0042207 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - "CG12294, CG18530" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG18530 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH1, Scer\YEH2, Scer\TGL1" "Cele\lipl-7, Cele\lipl-1, Cele\lipl-5, Cele\lipl-6, Cele\lipl-4, Cele\lipl-8, Cele\lipl-2, Cele\lipl-3" Xtro\lipa "Mmus\Lipf, Mmus\Lipn, Mmus\Lipk, Mmus\Lipm, Mmus\Lipo3, Mmus\Lipa, Mmus\Lipo2, Mmus\Lipo1, Mmus\Lipo4" "Hsap\LIPM, Hsap\LIPK, Hsap\LIPF, Hsap\LIPJ, Hsap\LIPN, Hsap\LIPA" viable DRSC15341 E 0.126313809 -0.815548406 3.197282764 -0.008054922 0.060502707 -0.525900322 FBgn0267649 pre-mod(mdg4)-H - http://flybase.org/reports/FBgn0267649 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-H, CG45987" "IPR007588:Zinc finger, FLYWCH-type" CG45987 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266762 CR45227 - http://flybase.org/reports/FBgn0266762 pseudogene_attribute - - - CR45227 - CR45227 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050412 CG30412 - http://flybase.org/reports/FBgn0050412 protein_coding_gene ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex III biogenesis ; GO:0097033 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 inner mitochondrial membrane organization ; GO:0007007 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 protein insertion into mitochondrial membrane from inner side ; GO:0032979 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex IV biogenesis ; GO:0097034 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 "CG9803, anon-WO0140519.195, CG30412" - CG30412 11-Aug-17 DroID_v2017_08 Drer\zgc:123096 Scer\MBA1 Cele\Y62E10A.20 - Mmus\Maip1 Hsap\MAIP1 viable FBgn0030898 Andorra Andorra http://flybase.org/reports/FBgn0030898 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12611, Andorra, and, andorra" - CG12611 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025709 CNT2 Concentrative nucleoside transporter 2 http://flybase.org/reports/FBgn0025709 FBgn0033370 protein_coding_gene nucleoside:sodium symporter activity ; GO:0005415 | inferred from biological aspect of ancestor with PANTHER:PTN000834192 "nucleoside transmembrane transport ; GO:1901642 | inferred from electronic annotation with InterPro:IPR008276, InterPro:IPR018270" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000063482 "BEST:CK00459, CK00459, DmCnt2, CNT2, CG8083" "IPR002668:Concentrative nucleoside transporter N-terminal domain, IPR008276:Concentrative nucleoside transporter, IPR011642:Nucleoside transporter/FeoB GTPase, Gate domain, IPR011657:Concentrative nucleoside transporter C-terminal domain, IPR018270:Concentrative nucleoside transporter, metazoan/bacterial" CG8083 11-Aug-17 DroID_v2017_08 Drer\slc28a1 - "Cele\slc-28.1, Cele\slc-28.2" "Xtro\slc28a2, Xtro\slc28a3" "Mmus\Gm14085, Mmus\Slc28a1, Mmus\Slc28a3, Mmus\Slc28a2" "Hsap\SLC28A2, Hsap\SLC28A1, Hsap\SLC28A3" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC07073 I 1.553097522 0.944152137 1.099184242 0.507491467 -0.255345893 -0.239562501 FBgn0065485 l(2)SH1263 lethal (2) SH1263 http://flybase.org/reports/FBgn0065485 gene - - - "l(2)SH1263, l(2)SH2 1263" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034312 CG10916 - http://flybase.org/reports/FBgn0034312 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1096377 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:1096377 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from sequence or structural similarity with MGI:MGI:1096377 cellular_component ; GO:0005575 | no biological data available CG10916 "IPR001841:Zinc finger, RING-type, IPR006616:DM9 repeat, IPR024518:Domain of unknown function DUF3421, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10916 11-Aug-17 DroID_v2017_08 "Drer\rnf2, Drer\lnx1, Drer\traip, Drer\si:ch211-207l14.1, Drer\lnx2b" - "Cele\spat-3, Cele\B0432.13, Cele\ZK637.14" "Xtro\traip, Xtro\rnf2" "Mmus\Traip, Mmus\Brca1, Mmus\Ring1, Mmus\Rnf2" "Hsap\BRCA1, Hsap\RNF2, Hsap\RING1, Hsap\PCGF1" "viable,fertile,long lived" FBgn0083289 E(smoDN)2047 Enhancer of smoDN 2047 http://flybase.org/reports/FBgn0083289 gene - - - E(smoDN)2047 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017385 l(1)15Eb lethal (1) 15Eb http://flybase.org/reports/FBgn0017385 - gene - - - l(1)15Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259730 tal-1A tarsal-less 1A http://flybase.org/reports/FBgn0259730 protein_coding_gene molecular_function ; GO:0003674 | no biological data available actin filament organization ; GO:0007015 | inferred from genetic interaction with tal morphogenesis of an epithelium ; GO:0002009 | inferred from genetic interaction with tal imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Dm1, tal-1A, CG42384, Pep1, ORF1, tal, ORF 1A, pri, Tal1A, Pri" - CG42384 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031663 CG8891 - http://flybase.org/reports/FBgn0031663 protein_coding_gene nucleoside-triphosphate diphosphatase activity ; GO:0047429 | inferred from biological aspect of ancestor with PANTHER:PTN000115987 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype nucleoside triphosphate catabolic process ; GO:0009143 | inferred from biological aspect of ancestor with PANTHER:PTN000115987 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000115987 CG8891 "IPR002637:Ham1-like protein, IPR029001:Inosine triphosphate pyrophosphatase-like, IPR027502:Inosine triphosphate pyrophosphatase" CG8891 11-Aug-17 DroID_v2017_08 Drer\itpa Scer\HAM1 Cele\hap-1 Xtro\itpa Mmus\Itpa Hsap\ITPA "viable,fertile" FBgn0005412 dsl diskless http://flybase.org/reports/FBgn0005412 "FBgn0000498, FBgn0001583, FBgn0001622, FBgn0004658" gene - - - "l(1)discless, l(1)discless-1, l(1)C154, l(1)dsl, l(1)dl-1, l(1)DF396, l(1)10Cf, dsl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,cell lethal,germline clone,lethal,mitotic cell cycle defective,some die during larval stage" "imaginal disc,cell cycle" FBgn0267744 CR46075 - http://flybase.org/reports/FBgn0267744 non_protein_coding_gene - - - "CR46075, lincRNA.255" - CR46075 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262036 CG42847 - http://flybase.org/reports/FBgn0262036 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42847 - CG42847 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264288 Su(Mir)3-1A2-2 - http://flybase.org/reports/FBgn0264288 gene - - - Su(Mir)3-1A2-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044005 Su(rst)C134 Su(rst)C134 http://flybase.org/reports/FBgn0044005 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C134, Su(rst)C134" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0037860 CG6629 - http://flybase.org/reports/FBgn0037860 protein_coding_gene succinate dehydrogenase activity ; GO:0000104 | inferred from electronic annotation with InterPro:IPR014314 tricarboxylic acid cycle ; GO:0006099 | inferred from electronic annotation with InterPro:IPR014314 succinate dehydrogenase complex ; GO:0045281 | inferred from electronic annotation with InterPro:IPR014314 CG6629 "IPR000701:Succinate dehydrogenase/Fumarate reductase, transmembrane subunit, IPR014314:Succinate dehydrogenase, cytochrome b556 subunit" CG6629 11-Aug-17 DroID_v2017_08 Drer\sdhc "Scer\SDH3, Scer\SHH3" Cele\mev-1 Xtro\sdhc Mmus\Sdhc Hsap\SDHC FBgn0067098 H70 H70 http://flybase.org/reports/FBgn0067098 gene - - - H70 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective,lethal,partially lethal - majority die" "chaeta,eye,pigment cell" FBgn0063375 snoRNA:Me28S-G3277a - http://flybase.org/reports/FBgn0063375 snoRNA_gene - - - "Snr38snoRNA, CR32893, snoRNA:snR38:54Ea, snoRNA:Me28S-G3277a, Me28S-G3277a, SnR38, snoRNA:MeS28-G3277a" - CR32893 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032455 Pih1D1 Pih1D1 http://flybase.org/reports/FBgn0032455 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay "CG5792, Pih1D1" IPR012981:PIH1 domain CG5792 11-Aug-17 DroID_v2017_08 "Drer\dnaaf2, Drer\pih1d2, Drer\pih1d1" Scer\PIH1 Cele\F32D8.4 "Xtro\dnaaf2, Xtro\pih1d1, Xtro\pih1d2" "Mmus\Pih1d2, Mmus\Dnaaf2, Mmus\Pih1d1" "Hsap\PIH1D2, Hsap\PIH1D1, Hsap\DNAAF2" viable FBgn0264914 CR44105 - http://flybase.org/reports/FBgn0264914 non_protein_coding_gene - - - CR44105 - CR44105 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036638 CG13033 - http://flybase.org/reports/FBgn0036638 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE50345, CG13033" IPR004019:YLP motif CG13033 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0066372 barb barbos http://flybase.org/reports/FBgn0066372 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "barb, barbos-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,chemical sensitive" FBgn0067417 His-Psi Histone pseudogene http://flybase.org/reports/FBgn0067417 pseudogene_attribute - - - His-Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045502 Gr10a Gustatory receptor 10a http://flybase.org/reports/FBgn0045502 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr10B1, CG32664, Gr10a, GR10a, gr10a" IPR013604:7TM chemoreceptor CG32664 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - "partially lethal - majority die,some die during pupal stage" DRSC18897 I -1.328997445 1.766443769 1.148231666 0.717794138 -0.523279283 -0.500800606 FBgn0262681 CR43151 - http://flybase.org/reports/FBgn0262681 non_protein_coding_gene - - - "CG43151, CR43151" - CR43151 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036868 ms(3)76Ba male sterile (3) 76Ba http://flybase.org/reports/FBgn0036868 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatogenesis ; GO:0007283 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG14087, ms(3)76Ba" - CG14087 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable" FBgn0266067 CR44820 - http://flybase.org/reports/FBgn0266067 non_protein_coding_gene - - - CR44820 - CR44820 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083124 Uhg4 Uhg4 http://flybase.org/reports/FBgn0083124 non_protein_coding_gene - - - "Uhg4, dUhg4, CR42451" - CR42451 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027294 l(1)G0150 lethal (1) G0150 http://flybase.org/reports/FBgn0027294 - gene - - - l(1)G0150 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "wing,eye" FBgn0026323 Tak1 TGF-beta activated kinase 1 http://flybase.org/reports/FBgn0026323 "FBgn0031120, FBgn0042230" protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR017421 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein binding ; GO:0005515 | inferred from physical interaction with S6k MAP kinase kinase kinase activity ; GO:0004709 | inferred from mutant phenotype MAP kinase kinase kinase activity ; GO:0004709 | traceable author statement ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with POSH protein kinase activity ; GO:0004672 | non-traceable author statement JUN kinase kinase kinase activity ; GO:0004706 | inferred from mutant phenotype" regulation of autophagy ; GO:0010506 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | traceable author statement dorsal closure ; GO:0007391 | traceable author statement activation of JNKK activity ; GO:0007256 | inferred from mutant phenotype innate immune response ; GO:0045087 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | inferred from genetic interaction with PGRP-LE dorsal closure ; GO:0007391 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from genetic interaction with hid inferred from genetic interaction with rpr inferred from genetic interaction with grim positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement cellular response to lipopolysaccharide ; GO:0071222 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype notum morphogenesis ; GO:0048802 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from genetic interaction with bsk inferred from genetic interaction with hep positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement I-kappaB kinase/NF-kappaB signaling ; GO:0007249 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "dTAK1, DTAK1, TAK, D-tak, dTak1, TAK-1, dTAK, tak1, TAK1, tak, D10, DmTak1, CG18492, CG1388, DTak1, DTak, Tak 1, Tak1, dtak1, dTAK-1, dTak, Tak, D-TAK" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017421:Mitogen-activated protein (MAP) kinase kinase kinase 7, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG18492 11-Aug-17 DroID_v2017_08 "Drer\LOC405768, Drer\map3k7, Drer\igf1rb, Drer\ripk2, Drer\ripk4, Drer\zak, Drer\mos, Drer\ripk3, Drer\dstyk, Drer\tyro3, Drer\ripk1l, Drer\ptk2aa, Drer\map3k10, Drer\tnk2b, Drer\si:ch211-120p12.3, Drer\map3k9, Drer\lrrk2, Drer\pbk" Scer\ARK1 "Cele\mom-4, Cele\kin-26, Cele\Y105C5A.24, Cele\let-23, Cele\F57B9.8" "Xtro\ripk1, Xtro\map3k7, Xtro\pbk, Xtro\abl2, Xtro\dstyk, Xtro\zak, Xtro\map3k9, Xtro\mlkl, Xtro\map3k10, Xtro\lrrk1, Xtro\ripk4, Xtro\lrrk2, Xtro\ankk1, Xtro\abl1, Xtro\LOC100490493" "Mmus\Pbk, Mmus\Mos, Mmus\Zak, Mmus\Map3k11, Mmus\Ripk3, Mmus\BC021891, Mmus\Mlkl, Mmus\Map3k9, Mmus\Ripk2, Mmus\Map3k7, Mmus\Ripk1, Mmus\Map3k10, Mmus\Lrrk1, Mmus\Ripk4, Mmus\Dstyk, Mmus\Lrrk2" "Hsap\DSTYK, Hsap\RIPK3, Hsap\MAP3K10, Hsap\LRRK1, Hsap\LRRK2, Hsap\PBK, Hsap\RIPK1, Hsap\RIPK4, Hsap\MAP3K7, Hsap\MAP3K11, Hsap\MAP3K20, Hsap\RIPK2, Hsap\MAP3K9, Hsap\MAP3K21, Hsap\MOS, Hsap\ABL1, Hsap\MLKL, Hsap\ALK" "visible,size defective,immune response defective,wild-type,viable,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,planar polarity defective,lethal" "eye,embryonic/first instar larval cuticle,anterior,pupa,eye disc,photoreceptor cell,denticle belt,denticle row 1,neuroblast | larval stage,mesothoracic tergum,microchaeta,embryonic head,mouth hooks,embryo,dorsal,interommatidial bristle,secondary pigment cell,tertiary pigment cell,eye photoreceptor cell,ommatidium,basement membraneptc-559.1" DRSC20390 I 0.406784594 -2.323382771 -0.285452844 0.024562052 0.02045284 -0.562214973 FBgn0082329 HM840 HM840 http://flybase.org/reports/FBgn0082329 gene - - - HM840 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083032 snoRNA:Psi18S-525g snoRNA:Psi18S-525g http://flybase.org/reports/FBgn0083032 snoRNA_gene - - - "snoRNA:Psi18S-525g, psi18S-525g, CR34580" - CR34580 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030895 CG7135 - http://flybase.org/reports/FBgn0030895 protein_coding_gene - - - CG7135 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG7135 11-Aug-17 DroID_v2017_08 - - "Cele\C29F7.1, Cele\nhr-246, Cele\H06H21.8, Cele\C29F7.2" - - - viable FBgn0043529 anon-AE003814.1 anon-AE003814.1 http://flybase.org/reports/FBgn0043529 gene - - - anon-AE003814.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022007 l(2)k09217 lethal (2) k09217 http://flybase.org/reports/FBgn0022007 - gene - - - l(2)k09217 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263379 CR43431 - http://flybase.org/reports/FBgn0263379 non_protein_coding_gene - - - CR43431 - CR43431 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024538 l(3)L1820 lethal (3) L1820 http://flybase.org/reports/FBgn0024538 - gene - - - l(3)L1820 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085295 CG34266 - http://flybase.org/reports/FBgn0085295 protein_coding_gene - - - CG34266 IPR007970:Protein of unknown function DUF733 CG34266 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001696 l(1)ESHS17 lethal (1) ESHS17 http://flybase.org/reports/FBgn0001696 - gene - - - l(1)ESHS17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0283657 Tlk Tousled-like kinase http://flybase.org/reports/FBgn0283657 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:11841 inferred from sequence or structural similarity with HGNC:11842 inferred from sequence or structural similarity with TAIR:gene:1944622 protein binding ; GO:0005515 | inferred from physical interaction with asf1 protein kinase activity ; GO:0004672 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay" "chromatin organization ; GO:0006325 | inferred from genetic interaction with asf1 protein phosphorylation ; GO:0006468 | inferred from direct assay mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype histone phosphorylation ; GO:0016572 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay chromosome segregation ; GO:0007059 | inferred from genetic interaction with mars antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement" heterochromatin ; GO:0000792 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "tlk, Tlk, CG34412, CG32782, CG2829, BcDNA:GH07910, l(1)G0054, CG33219, dtlk, anon-WO03040301.116, anon-WO03040301.114, CG32781, EP1413, EP(X)1413, CG12462, TLK, GH17330, EP(X)1408, BEST:GH17330, EP1408" "IPR017441:Protein kinase, ATP binding site, IPR011009:Protein kinase-like domain, IPR008271:Serine/threonine-protein kinase, active site, IPR000719:Protein kinase domain" CG34412 11-Aug-17 DroID_v2017_08 "Drer\tlk1a, Drer\slc25a12, Drer\tlk2, Drer\tlk1b" "Scer\RTK1, Scer\NPR1, Scer\MPS1, Scer\PRR2, Scer\HRK1" "Cele\T07F12.4, Cele\tlk-1" Xtro\tlk2 "Mmus\Tlk1, Mmus\Tlk2" "Hsap\TLK1, Hsap\TLK2" DRSC22926 IEK 1.810233974 0.126963814 2.051290113 -3.806916791 -2.466977625 0.333336039 FBgn0085621 CG41335 - http://flybase.org/reports/FBgn0085621 protein_coding_gene - - - CG41335 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040723 CG5011 - http://flybase.org/reports/FBgn0040723 protein_coding_gene - - - CG5011 - CG5011 11-Aug-17 DroID_v2017_08 - - - - - Hsap\PHGR1 viable FBgn0026088 CG14818 - http://flybase.org/reports/FBgn0026088 "FBgn0047006, FBgn0047172" protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CT34631, EG:63B12.12, BcDNA:RH52516, BcDNA:RE09176, CG14818" "IPR005374:Uncharacterised protein family UPF0184, eukaryota, IPR022788:Uncharacterised protein family UPF0184" CG14818 11-Aug-17 DroID_v2017_08 Drer\gb:bc139872 "Scer\TVP15, Scer\NSE5, Scer\MND1" Cele\pdl-1 - "Mmus\Pde6d, Mmus\1110008P14Rik" "Hsap\C9orf16, Hsap\PDE6D" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030640 CG6294 - http://flybase.org/reports/FBgn0030640 protein_coding_gene metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR024079 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG6294 "IPR024079:Metallopeptidase, catalytic domain, IPR021917:Uncharacterised protein family, zinc metallopeptidase-like" CG6294 11-Aug-17 DroID_v2017_08 - Scer\YIL108W - - - - "visible,partially lethal - majority die,some die during pupal stage" "mesothoracic tergum,trichogen cell" FBgn0065780 l(2)SH0444 lethal (2) SH0444 http://flybase.org/reports/FBgn0065780 gene - - - "l(2)SH0444, l(2)SH2 0444" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001812 l(1)nc1 lethal (1) nc1 http://flybase.org/reports/FBgn0001812 - gene - - - "l(1)1308, l(1)nc1" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032348 CG4751 - http://flybase.org/reports/FBgn0032348 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4751, Q9VKJ1" "IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG4751 11-Aug-17 DroID_v2017_08 "Drer\mpnd, Drer\mysm1, Drer\psmd14, Drer\brcc3" Scer\RPN11 - "Xtro\psmd14, Xtro\mpnd, Xtro\mysm1, Xtro\brcc3" "Mmus\Brcc3, Mmus\Mpnd, Mmus\Mysm1, Mmus\Psmd14" "Hsap\BRCC3, Hsap\PSMD14, Hsap\MPND, Hsap\MYSM1" viable FBgn0263328 CR43409 - http://flybase.org/reports/FBgn0263328 non_protein_coding_gene - - - CR43409 - CR43409 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015901 anon-P1609-III anon-P1609-III http://flybase.org/reports/FBgn0015901 - gene - - - anon-P1609-III - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082626 S(CycE[JP])3.2 S(CycE[JP])3.2 http://flybase.org/reports/FBgn0082626 gene - - - S(CycE[JP])3.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0020534 l(2)k09201 lethal (2) k09201 http://flybase.org/reports/FBgn0020534 - gene - - - "l(2)09201, l(2)k09201" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052815 CG32815 - http://flybase.org/reports/FBgn0052815 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18830, CG16994, CG32815" - CG32815 11-Aug-17 DroID_v2017_08 "Drer\zgc:113278, Drer\tram2, Drer\tram1" - Cele\tram-1 "Xtro\tram2, Xtro\tram1" "Mmus\Tram2, Mmus\Tram1, Mmus\Tram1l1" "Hsap\TRAM2, Hsap\TRAM1L1" "viable,fertile" FBgn0031814 retm real-time http://flybase.org/reports/FBgn0031814 protein_coding_gene - transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 mitochondrion ; GO:0005739 | inferred from direct assay "CG9528, retm" "IPR001251:CRAL-TRIO lipid binding domain, IPR006797:PRELI/MSF1 domain, IPR009038:GOLD domain, IPR011074:CRAL/TRIO, N-terminal domain" CG9528 11-Aug-17 DroID_v2017_08 "Drer\sec14l7, Drer\ttpal, Drer\sec14l8, Drer\sec14l1, Drer\si:dkey-237i9.1, Drer\rlbp1a, Drer\clvs2, Drer\ttpa" "Scer\SFH5, Scer\SEC14, Scer\YKL091C" "Cele\T23G5.2, Cele\T03F7.7, Cele\ctg-1" "Xtro\clvs2, Xtro\mospd2, Xtro\sec14l3, Xtro\ttpa, Xtro\clvs1, Xtro\sec14l1, Xtro\rlbp1, Xtro\sec14l5, Xtro\ttpal" "Mmus\Sec14l1, Mmus\Sec14l3, Mmus\Rlbp1, Mmus\Clvs2, Mmus\Ttpal, Mmus\Sec14l4, Mmus\Clvs1, Mmus\Sec14l5, Mmus\Ttpa, Mmus\Sec14l2" "Hsap\SEC14L1, Hsap\SEC14L6, Hsap\CLVS2, Hsap\CLVS1, Hsap\TTPAL, Hsap\SEC14L4, Hsap\SEC14L5, Hsap\RLBP1, Hsap\TTPA, Hsap\SEC14L2, Hsap\SEC14L3" viable FBgn0062690 EP1371 EP1371 http://flybase.org/reports/FBgn0062690 gene - - - "EP(X)1371, EP1371" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000836 fs(1)M20 female sterile (1) M20 http://flybase.org/reports/FBgn0000836 - gene - - - fs(1)M20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0266230 CR44925 - http://flybase.org/reports/FBgn0266230 non_protein_coding_gene - - - "CR44925, lincRNA.684" - CR44925 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065784 l(2)SH0438 lethal (2) SH0438 http://flybase.org/reports/FBgn0065784 gene - - - "l(2)SH0438, l(2)SH2 0438" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022706 Ca-1 Carbonic anhydrase-1 http://flybase.org/reports/FBgn0022706 - gene - - - "CA-1, Ca-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266572 ebo ellipsoid body open http://flybase.org/reports/FBgn0266572 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001494 central complex development ; GO:0048036 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | traceable author statement flight behavior ; GO:0007629 | inferred from mutant phenotype - "EG:165H7.3, ebo, CG3923, Exp1, Exp6, EBO" "IPR001494:Importin-beta, N-terminal domain, IPR016024:Armadillo-type fold, IPR013598:Exportin-1/Importin-beta-like, IPR011989:Armadillo-like helical" CG3923 11-Aug-17 DroID_v2017_08 "Drer\xpo1b, Drer\xpo6, Drer\xpo1a, Drer\xpo5" "Scer\CRM1, Scer\MSN5" - "Xtro\xpo5, Xtro\xpo6, Xtro\xpo1, Xtro\exd3" "Mmus\Xpo1, Mmus\Xpo6, Mmus\Xpo5" "Hsap\XPO1, Hsap\XPO5, Hsap\XPO6" FBgn0034317 CG14499 - http://flybase.org/reports/FBgn0034317 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14499, CR14499" "IPR016187:C-type lectin fold, IPR016186:C-type lectin-like/link domain, IPR001304:C-type lectin-like" CG14499 11-Aug-17 DroID_v2017_08 - - Cele\clec-225 - - - FBgn0083315 E(smoDN)1171 Enhancer of smoDN 1171 http://flybase.org/reports/FBgn0083315 gene - - - E(smoDN)1171 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267783 CR46114 - http://flybase.org/reports/FBgn0267783 non_protein_coding_gene - - - CR46114 - CR46114 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027964 l(3)S145511 lethal (3) S145511 http://flybase.org/reports/FBgn0027964 gene - - - "1455/11, l(3)S145511" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0086661 snoRNA:Psi28S-2566 snoRNA:Psi28S-2566 http://flybase.org/reports/FBgn0086661 snoRNA_gene - - - "snoRNA:269, psi28s-2566, Psi28S-2566(SnoR269), snoRNA:Psi28S-2566, Dm-269, snoR269, CR33686, Psi28S-2566, chr3L:18861298..18861726" - CR33686 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266974 CR45425 - http://flybase.org/reports/FBgn0266974 non_protein_coding_gene - - - CR45425 - CR45425 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036953 CG17145 - http://flybase.org/reports/FBgn0036953 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG17145 IPR002557:Chitin binding domain CG17145 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\C39D10.7, Cele\cpg-1, Cele\R02F2.4, Cele\cpg-2" - - Hsap\MATN2 FBgn0011058 l(1)Q11 lethal (1) Q11 http://flybase.org/reports/FBgn0011058 FBgn0010210 gene - - - l(1)Q11 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0066370 btx bellatrix http://flybase.org/reports/FBgn0066370 gene - - - btx - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031446 CG15398 - http://flybase.org/reports/FBgn0031446 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000814 "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR000814" - CG15398 IPR000814:TATA-box binding protein CG15398 11-Aug-17 DroID_v2017_08 "Drer\tbp, Drer\tbpl1, Drer\tbpl2" Scer\SPT15 "Cele\tlf-1, Cele\tbp-1" "Xtro\tbpl2, Xtro\tbp, Xtro\tbpl1" "Mmus\Tbp, Mmus\Tbpl2, Mmus\Tbpl1" "Hsap\TBP, Hsap\TBPL1, Hsap\TBPL2" viable FBgn0000057 adp adipose http://flybase.org/reports/FBgn0000057 "FBgn0034305, FBgn0061182" protein_coding_gene molecular_function ; GO:0003674 | no biological data available lipid metabolic process ; GO:0006629 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype negative regulation of sequestering of triglyceride ; GO:0010891 | inferred from mutant phenotype carbohydrate metabolic process ; GO:0005975 | traceable author statement response to desiccation ; GO:0009269 | inferred from mutant phenotype lipid metabolic process ; GO:0006629 | traceable author statement cellular_component ; GO:0005575 | no biological data available "anon-WO0196371.3, anon-WO0196371.1, CG5124, anon-WO0196371.27, adp" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR019775:WD40 repeat, conserved site" CG5124 11-Aug-17 DroID_v2017_08 "Drer\wdtc1, Drer\dcaf8" Scer\COP1 Cele\adpr-1 "Xtro\dcaf8, Xtro\dcaf6, Xtro\wdtc1" "Mmus\Dcaf8, Mmus\Wdtc1, Mmus\Dcaf6" "Hsap\DCAF8, Hsap\DCAF6, Hsap\WDTC1" "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,male fertile,female fertile,stress response defective,locomotor behavior defective,recessive,starvation stress response defective,dominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/larval fat body,fat body,adult fat body,yolk,adult corpus allatum,dorsal appendage,oocyte,female,lipid particle" FBgn0037623 CG9801 - http://flybase.org/reports/FBgn0037623 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001932 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9801 IPR001932:PPM-type phosphatase domain CG9801 11-Aug-17 DroID_v2017_08 - - Cele\F33G12.6 - - - FBgn0261928 CG42795 - http://flybase.org/reports/FBgn0261928 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 "CG42795, CG3996, CG12816, CG34108" "IPR032738:TBC1 domain family member 30, C-terminal, IPR000195:Rab-GTPase-TBC domain" CG42795 11-Aug-17 DroID_v2017_08 "Drer\tbc1d2, Drer\grtp1a, Drer\grtp1b, Drer\tbc1d8, Drer\tbc1d30, Drer\tbc1d9b, Drer\tbc1d2b, Drer\si:dkey-110k5.6, Drer\tbc1d9" "Scer\BUB2, Scer\MSB3, Scer\MDR1, Scer\MSB4" "Cele\tbc-9, Cele\tbc-19, Cele\tbc-18, Cele\tbc-2" "Xtro\grtp1, Xtro\tbc1d30, Xtro\tbc1d2b" "Mmus\Tbc1d9b, Mmus\Tbc1d2b, Mmus\Tbc1d8, Mmus\Grtp1, Mmus\Tbc1d2, Mmus\Tbc1d30, Mmus\Tbc1d9, Mmus\Tbc1d8b" "Hsap\GRTP1, Hsap\TBC1D9B, Hsap\TBC1D8B, Hsap\TBC1D8, Hsap\TBC1D2B, Hsap\TBC1D30, Hsap\TBC1D9, Hsap\TBC1D2" FBgn0053476 CG33476 - http://flybase.org/reports/FBgn0053476 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33476 IPR010512:Protein of unknown function DUF1091 CG33476 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065822 l(2)SH0366 lethal (2) SH0366 http://flybase.org/reports/FBgn0065822 gene - - - "l(2)SH0366, l(2)SH2 0366" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003072 pg prong http://flybase.org/reports/FBgn0003072 - gene - - - pg - - 11-Aug-17 DroID_v2017_08 - - - - - - crossvein FBgn0264959 Src42A Src oncogene at 42A http://flybase.org/reports/FBgn0264959 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357" "adherens junction organization ; GO:0034332 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Ras85D tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from genetic interaction with Fak apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 axon guidance ; GO:0007411 | inferred from mutant phenotype JNK cascade ; GO:0007254 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype inferred from genetic interaction with FER cell migration ; GO:0016477 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay inferred from mutant phenotype epithelial cell-cell adhesion ; GO:0090136 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype regulation of synaptic plasticity ; GO:0048167 | inferred from genetic interaction with GluRIIA dorsal closure ; GO:0007391 | traceable author statement salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype inferred from genetic interaction with bsk inferred from genetic interaction with hep inferred from genetic interaction with Src64B regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from genetic interaction with Raf" adherens junction ; GO:0005912 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 "Src42, Src42A, Src, CG44128, src42A, DSrc42A, src42, Dsrc42A, SRC 42A, CG7873, SK2-4, src, Dsrc41, dtk5, DmHD-29, Src41, Su(Raf)1, Su1, Dm SRC41, dtk-5, Su(phl)1, Su(D-raf)1, SRC42A, l(2)k10108, Tk5, HD-29, Dtk5, dSrc, Src42a, src42a, CG14471" "IPR011009:Protein kinase-like domain, IPR000719:Protein kinase domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR008266:Tyrosine-protein kinase, active site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR017441:Protein kinase, ATP binding site, IPR001452:SH3 domain, IPR000980:SH2 domain" CG44128 11-Aug-17 DroID_v2017_08 "Drer\sla1, Drer\btk, Drer\itk, Drer\jak3, Drer\zgc:194282, Drer\yrk, Drer\matk, Drer\yes1, Drer\ptk6b, Drer\sla, Drer\lyn, Drer\hck, Drer\src, Drer\jak1, Drer\csk, Drer\jak2b, Drer\abl1, Drer\si:ch73-340m8.2, Drer\fyna, Drer\ptk6a, Drer\lck, Drer\tec, Drer\fynb, Drer\abl2, Drer\frk, Drer\tyk2, Drer\jak2a, Drer\txk" - "Cele\src-2, Cele\F39B2.5, Cele\src-1, Cele\Y38H6C.20, Cele\abl-1, Cele\Y47G6A.5" "Xtro\csk, Xtro\lyn, Xtro\jak1, Xtro\frk, Xtro\abl2, Xtro\lck, Xtro\tyk2, Xtro\jak3, Xtro\abl1, Xtro\jak2, Xtro\tec, Xtro\src, Xtro\fgr, Xtro\yes1, Xtro\btk, Xtro\fyn" "Mmus\Fyn, Mmus\Srms, Mmus\Src, Mmus\Csk, Mmus\Hck, Mmus\Blk, Mmus\Jak2, Mmus\Btk, Mmus\Abl1, Mmus\Bmx, Mmus\Txk, Mmus\Yes1, Mmus\Jak3, Mmus\Abl2, Mmus\Frk, Mmus\Lck, Mmus\Sla, Mmus\Tyk2, Mmus\Ptk6, Mmus\Itk, Mmus\Sla2, Mmus\Tec, Mmus\Lyn, Mmus\Fgr, Mmus\Jak1, Mmus\Matk" "Hsap\SLA, Hsap\ABL1, Hsap\FRK, Hsap\JAK3, Hsap\ABL2, Hsap\FGR, Hsap\ITK, Hsap\CSK, Hsap\YES1, Hsap\TXK, Hsap\FYN, Hsap\BLK, Hsap\BMX, Hsap\MATK, Hsap\TYK2, Hsap\JAK1, Hsap\SRMS, Hsap\SRC, Hsap\LYN, Hsap\JAK2, Hsap\BTK, Hsap\SLA2, Hsap\PTK6, Hsap\LCK, Hsap\HCK, Hsap\TEC" " embryonic stage | stage 13-16 , larval stage | third instar , embryonic stage&&pupal stage , embryonic stage | early " " visceral mesoderm

, ventral thoracic disc

, supraesophageal ganglion

, anal pad

, embryonic/larval hindgut

, eye-antennal disc

, dorsal mesothoracic disc

, ventral nerve cord

, central nervous system

,

ubiquitous " DRSC04915 IEK -0.580107243 -3.939586829 -0.874133636 -6.546117287 -3.99074456 -2.832864398 FBgn0004688 pby pebbly http://flybase.org/reports/FBgn0004688 - gene - - - pby - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,ommatidium" FBgn0034475 Obp56h Odorant-binding protein 56h http://flybase.org/reports/FBgn0034475 protein_coding_gene odorant binding ; GO:0005549 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 olfactory behavior ; GO:0042048 | inferred from sequence or structural similarity with UniProtKB:O02372 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 response to pheromone ; GO:0019236 | inferred from sequence or structural similarity with UniProtKB:O02372 sensory perception of smell ; GO:0007608 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:O02372 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "Obp56h, 56h, CG13874, OBP56h, DmelObp56h" IPR006170:Pheromone/general odorant binding protein CG13874 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0017629 Eig34C Eig34C http://flybase.org/reports/FBgn0017629 - gene - - - "Eig34, Eig34C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032804 CG13081 - http://flybase.org/reports/FBgn0032804 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13081 - CG13081 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037916 CG5342 - http://flybase.org/reports/FBgn0037916 protein_coding_gene mannose-ethanolamine phosphotransferase activity ; GO:0051377 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 CG5342 "IPR007070:GPI ethanolamine phosphate transferase 1, IPR017852:GPI ethanolamine phosphate transferase 1, C-terminal" CG5342 11-Aug-17 DroID_v2017_08 Drer\pign Scer\MCD4 Cele\Y54E10BR.1 - Mmus\Pign Hsap\PIGN "viable,fertile" FBgn0010131 l(1)tsW2 lethal (1) tsW2 http://flybase.org/reports/FBgn0010131 - gene - - - l(1)tsW2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0022260 l(2)k00803 lethal (2) k00803 http://flybase.org/reports/FBgn0022260 - gene - - - l(2)k00803 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033653 CG13192 - http://flybase.org/reports/FBgn0033653 protein_coding_gene molecular_function ; GO:0003674 | no biological data available social behavior ; GO:0035176 | inferred from sequence or structural similarity with MGI:MGI:1338057 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:1338057 CG13192 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG13192 11-Aug-17 DroID_v2017_08 Drer\gnb1l - "Cele\C10B5.1, Cele\mec-15" Xtro\gnb1l Mmus\Gnb1l Hsap\GNB1L viable FBgn0035353 CG18334 - http://flybase.org/reports/FBgn0035353 protein_coding_gene - - - CG18334 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031887 CG11289 - http://flybase.org/reports/FBgn0031887 protein_coding_gene "transferase activity, transferring hexosyl groups ; GO:0016758 | inferred from electronic annotation with InterPro:IPR002213 UDP-glycosyltransferase activity ; GO:0008194 | inferred from biological aspect of ancestor with PANTHER:PTN000230403" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG11289 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG11289 11-Aug-17 DroID_v2017_08 "Drer\ugt1b2, Drer\ugt5f1, Drer\zgc:172315, Drer\ugt5b1, Drer\ugt5a1, Drer\ugt5b3, Drer\ugt5b2, Drer\ugt5b6, Drer\ugt5c2, Drer\ugt5g1, Drer\ugt5d1, Drer\ugt5c1, Drer\ugt2a2, Drer\ugt2a5, Drer\ugt1ab, Drer\ugt1b3, Drer\ugt5g2, Drer\ugt1b4, Drer\ugt5a2, Drer\ugt2b5, Drer\ugt5c3, Drer\ugt2b6, Drer\ugt1b7, Drer\ugt2b3, Drer\ugt8, Drer\ugt2a6, Drer\ugt5a4, Drer\ugt5e1, Drer\ugt1b5, Drer\ugt2b1, Drer\ugt5a5" Scer\ATG26 "Cele\C03A7.12, Cele\ugt-35, Cele\ugt-27, Cele\ugt-22, Cele\ugt-30, Cele\ugt-23, Cele\ugt-28, Cele\ugt-13, Cele\ugt-51, Cele\ugt-65, Cele\ugt-38, Cele\ugt-25, Cele\ugt-14, Cele\ugt-57, Cele\ugt-5, Cele\ugt-31, Cele\ugt-20, Cele\ugt-4, Cele\ugt-9, Cele\ugt-39, Cele\ugt-11, Cele\ugt-10, Cele\ugt-15, Cele\ugt-62, Cele\ugt-7, Cele\ugt-42, Cele\ugt-17, Cele\ugt-37, Cele\ugt-44, Cele\ugt-58, Cele\ugt-34, Cele\ugt-36, Cele\ugt-53, Cele\ugt-61, Cele\ugt-6, Cele\ugt-2, Cele\ugt-45, Cele\ugt-3, Cele\C55H1.1, Cele\ugt-55, Cele\ugt-19, Cele\ugt-26, Cele\ugt-52, Cele\ugt-1, Cele\ugt-24, Cele\ugt-18, Cele\ugt-29, Cele\K04A8.10, Cele\ugt-48, Cele\ugt-43, Cele\ugt-47, Cele\ugt-50, Cele\ugt-59, Cele\Y43D4A.2, Cele\C03A7.13, Cele\C23G10.6, Cele\ugt-32, Cele\ugt-21, Cele\ugt-60, Cele\ugt-54, Cele\ugt-41, Cele\ugt-16, Cele\H23N18.4, Cele\ugt-33, Cele\F10D2.8, Cele\ugt-56, Cele\ugt-12, Cele\ugt-49, Cele\ugt-46, Cele\ugt-8, Cele\ugt-40" "Xtro\ugt2a1, Xtro\ugt1a6, Xtro\ugt2b4, Xtro\ugt3a2, Xtro\ugt8" "Mmus\Ugt2a3, Mmus\Ugt3a1, Mmus\Ugt1a5, Mmus\Ugt1a9, Mmus\Ugt2b1, Mmus\Ugt1a1, Mmus\Ugt2b5, Mmus\Ugt1a6b, Mmus\Ugt1a2, Mmus\Ugt2b35, Mmus\Ugt3a2, Mmus\Ugt2b34, Mmus\Ugt2b38, Mmus\Ugt2a1, Mmus\Ugt1a7c, Mmus\Ugt8a, Mmus\Ugt2b36, Mmus\Ugt2b37" "Hsap\UGT2B11, Hsap\UGT2A3, Hsap\UGT1A10, Hsap\UGT8, Hsap\UGT1A4, Hsap\UGT2B4, Hsap\UGT1A9, Hsap\UGT2B7, Hsap\UGT3A1, Hsap\UGT2B17, Hsap\UGT1A5, Hsap\UGT1A6, Hsap\UGT1A3, Hsap\UGT2B28, Hsap\UGT1A1, Hsap\UGT2A2, Hsap\UGT1A7, Hsap\UGT1A8, Hsap\UGT3A2, Hsap\UGT2B15, Hsap\UGT2B10" "viable,visible" mesothoracic tergum FBgn0022014 l(2)k09035 lethal (2) k09035 http://flybase.org/reports/FBgn0022014 - gene - - - l(2)k09035 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021766 s3754 s3754 http://flybase.org/reports/FBgn0021766 - gene - - - s3754 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0265351 nac neuronally altered carbohydrate http://flybase.org/reports/FBgn0265351 protein_coding_gene UDP-galactose transmembrane transporter activity ; GO:0005459 | NOT inferred from direct assay GDP-fucose transmembrane transporter activity ; GO:0005457 | inferred from direct assay UDP-N-acetylgalactosamine transmembrane transporter activity ; GO:0005463 | NOT inferred from direct assay UDP-N-acetylglucosamine transmembrane transporter activity ; GO:0005462 | NOT inferred from direct assay GDP-mannose transmembrane transporter activity ; GO:0005458 | NOT inferred from direct assay CMP-N-acetylneuraminate transmembrane transporter activity ; GO:0005456 | NOT inferred from direct assay UDP-glucuronic acid transmembrane transporter activity ; GO:0005461 | NOT inferred from direct assay UDP-glucose transmembrane transporter activity ; GO:0005460 | NOT inferred from direct assay GDP-fucose transmembrane transporter activity ; GO:0005457 | inferred from mutant phenotype "Golgi vesicle transport ; GO:0048193 | inferred from direct assay UDP-glucuronic acid transport ; GO:0015787 | NOT inferred from direct assay CMP-N-acetylneuraminate transport ; GO:0015782 | NOT inferred from direct assay GDP-fucose transport ; GO:0015783 | inferred from direct assay protein O-linked fucosylation ; GO:0036066 | inferred from mutant phenotype grooming behavior ; GO:0007625 | inferred from mutant phenotype N-glycan fucosylation ; GO:0036071 | inferred from mutant phenotype UDP-N-acetylglucosamine transport ; GO:0015788 | NOT inferred from direct assay GDP-fucose import into Golgi lumen ; GO:0036085 | inferred by curator from GO:0005457,GO:0005794 UDP-galactose transport ; GO:0015785 | NOT inferred from direct assay GDP-mannose transport ; GO:0015784 | NOT inferred from direct assay UDP-N-acetylgalactosamine transport ; GO:0015789 | NOT inferred from direct assay GDP-fucose import into Golgi lumen ; GO:0036085 | inferred from direct assay inferred from mutant phenotype UDP-glucose transport ; GO:0015786 | NOT inferred from direct assay" Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi-associated vesicle ; GO:0005798 | inferred from direct assay "Gfr, nac, gfr, CG9620, Nac" IPR004853:Sugar phosphate transporter domain CG9620 11-Aug-17 DroID_v2017_08 Drer\slc35c1 - "Cele\nstp-10, Cele\nstp-9" Xtro\slc35c1 Mmus\Slc35c1 Hsap\SLC35C1 FBgn0000361 Cp70 Chorion protein 70 http://flybase.org/reports/FBgn0000361 - gene structural constituent of chorion ; GO:0005213 | inferred from direct assay eggshell chorion assembly ; GO:0007306 | inferred from direct assay - "s70, Cp70" - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0028541 TM9SF4 Transmembrane 9 superfamily protein member 4 http://flybase.org/reports/FBgn0028541 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence or structural similarity phagocytosis ; GO:0006909 | inferred from mutant phenotype encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype negative regulation of peptidoglycan recognition protein signaling pathway ; GO:0061060 | inferred from mutant phenotype protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000080197 "n(2)k07245, BG:DS00797.1, CG16861, TM9SF4, CG7364" IPR004240:Nonaspanin (TM9SF) CG7364 11-Aug-17 DroID_v2017_08 "Drer\top3a, Drer\tm9sf2, Drer\tm9sf4, Drer\LOC558202" "Scer\TMN3, Scer\EMP70, Scer\TMN2" "Cele\tag-123, Cele\top-3, Cele\ZK858.6" "Xtro\LOC100489507, Xtro\tm9sf2, Xtro\top3a" "Mmus\Tm9sf2, Mmus\Top3a, Mmus\Tm9sf4, Mmus\Gm364" "Hsap\TM9SF4, Hsap\TOP3A, Hsap\TM9SF2" "viable,fertile,immune response defective,partially lethal - majority live,wild-type,lethal - all die before end of pupal stage,some die during pupal stage" "plasmatocyte,sessile hemocyte,actin cytoskeleton & plasmatocyte" FBgn0050172 CG30172 - http://flybase.org/reports/FBgn0050172 protein_coding_gene - - extracellular region ; GO:0005576 | inferred from sequence model "anon-AE003462.1, BcDNA:RH70879, CG30172, DmelCSP1" IPR005055:Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 CG30172 11-Aug-17 DroID_v2017_08 Drer\ifit15 - - - - - viable DRSC30069 K 0.112266434 0.467004458 0.457108159 -0.03190613 0.571615307 1.678506683 FBgn0011277 HLH4C Helix loop helix protein 4C http://flybase.org/reports/FBgn0011277 - protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001015390 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001015390" regulation of cell cycle ; GO:0051726 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001015390 "DroNHLH, EG:84H4.2, CG3052, HLH4C, bHLH36" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG3052 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-246m6.4, Drer\tcf15, Drer\tal1, Drer\nhlh2, Drer\tcf23, Drer\msc, Drer\tal2, Drer\ascl1b, Drer\tcf24, Drer\hand2, Drer\ascl1a, Drer\mespaa, Drer\scxa, Drer\mespab, Drer\ptf1a, Drer\atoh1c, Drer\figla, Drer\msgn1, Drer\tcf21, Drer\mespba, Drer\lyl1, Drer\scxb" - "Cele\hlh-15, Cele\hlh-3, Cele\hlh-13, Cele\hlh-12, Cele\lin-32" "Xtro\tal1, Xtro\ascl3, Xtro\hand2, Xtro\mespb, Xtro\ascl2, Xtro\figla, Xtro\msc, Xtro\scx, Xtro\nhlh1, Xtro\mespa, Xtro\ptf1a, Xtro\tcf21, Xtro\msgn1, Xtro\hand1, Xtro\lyl1, Xtro\tcf15" "Mmus\Msc, Mmus\Ascl3, Mmus\Tal1, Mmus\Hand2, Mmus\Tal2, Mmus\Mesp2, Mmus\Mesp1, Mmus\Msgn1, Mmus\Tcf15, Mmus\Ptf1a, Mmus\Ferd3l, Mmus\Nhlh1, Mmus\Hand1, Mmus\Ascl1, Mmus\Tcf21, Mmus\Lyl1, Mmus\Figla, Mmus\Ascl5, Mmus\Nhlh2, Mmus\Ascl4, Mmus\Scx, Mmus\Tcf23" "Hsap\MSGN1, Hsap\ASCL1, Hsap\NHLH2, Hsap\NHLH1, Hsap\ASCL5, Hsap\TAL2, Hsap\TAL1, Hsap\MESP2, Hsap\HAND1, Hsap\TCF15, Hsap\TCF21, Hsap\ASCL4, Hsap\MESP1, Hsap\TCF24, Hsap\ASCL3, Hsap\LYL1, Hsap\FIGLA, Hsap\TCF23, Hsap\SCX, Hsap\PTF1A, Hsap\MSC, Hsap\HAND2" " embryonic stage | stage >=12 , embryonic stage " " embryonic central nervous system | restricted

, neuron

" viable DRSC18670 I -1.56652381 0.309846124 0.08543051 0.579377511 0.262325871 0.52791879 FBgn0038132 CG15887 - http://flybase.org/reports/FBgn0038132 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE53127, CG15887" - CG15887 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001807 l(1)Mc52 lethal (1) Mc52 http://flybase.org/reports/FBgn0001807 - gene - - - l(1)Mc52 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041122 l(2)45Be lethal (2) 45Be http://flybase.org/reports/FBgn0041122 gene - - - l(2)45Be - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0265929 CR44718 - http://flybase.org/reports/FBgn0265929 non_protein_coding_gene - - - CR44718 - CR44718 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041157 en::ovo en::ovo http://flybase.org/reports/FBgn0041157 engineered_fusion_gene - - - en::ovo - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,embryonic/first instar larval cuticle,denticle belt" FBgn0005100 fs(3)350-7 female sterile (3) 350-7 http://flybase.org/reports/FBgn0005100 - gene - - - fs(3)350-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "dorsal appendage,endochorion" FBgn0266893 CR45353 - http://flybase.org/reports/FBgn0266893 non_protein_coding_gene - - - CR45353 - CR45353 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259667 B0748 - http://flybase.org/reports/FBgn0259667 gene - - - B0748 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein L3 FBgn0265963 CR44750 - http://flybase.org/reports/FBgn0265963 non_protein_coding_gene - - - CR44750 - CR44750 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035138 CG13884 - http://flybase.org/reports/FBgn0035138 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT18596, CG13884" - CG13884 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0267198 CR45638 - http://flybase.org/reports/FBgn0267198 non_protein_coding_gene - - - CR45638 - CR45638 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001870 l(1)XD03 lethal (1) XD03 http://flybase.org/reports/FBgn0001870 - gene - - - l(1)XD03 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005336 podM podoptera in M(3)w 124 http://flybase.org/reports/FBgn0005336 - gene - - - "pod-M, podM" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0014978 l(2)23Ab lethal (2) 23Ab http://flybase.org/reports/FBgn0014978 - gene molecular_function ; GO:0003674 | no biological data available nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)23Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,some die during larval stage" "peripheral nervous system,central nervous system,peripheral nervous system precursor cluster" FBgn0032266 CG18302 - http://flybase.org/reports/FBgn0032266 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - CG18302 "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG18302 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH2, Scer\TGL1, Scer\YEH1" "Cele\lipl-7, Cele\lipl-6, Cele\lipl-8, Cele\lipl-3, Cele\lipl-4, Cele\lipl-1, Cele\lipl-2, Cele\lipl-5" Xtro\lipa "Mmus\Lipo3, Mmus\Lipo2, Mmus\Lipf, Mmus\Lipo1, Mmus\Lipa, Mmus\Lipk, Mmus\Lipo4, Mmus\Lipn, Mmus\Lipm" "Hsap\LIPN, Hsap\LIPJ, Hsap\LIPM, Hsap\LIPF, Hsap\LIPK, Hsap\LIPA" viable FBgn0028250 l(3)91Ce lethal (3) 91Ce http://flybase.org/reports/FBgn0028250 gene - - - l(3)91Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065370 l(2)SH1702 lethal (2) SH1702 http://flybase.org/reports/FBgn0065370 gene - - - "l(2)SH1702, l(2)SH2 1702" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264361 CG43813 - http://flybase.org/reports/FBgn0264361 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43813 - CG43813 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045864 blood\ORF2 blood element ORF2 http://flybase.org/reports/FBgn0045864 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - blood\ORF2 "IPR026523:Paraneoplastic antigen Ma, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR015416:Zinc finger, H2C2-type, histone UAS binding, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062639 EP924 EP924 http://flybase.org/reports/FBgn0062639 gene - - - "EP(3)0924, EP924" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263780 CG17684 - http://flybase.org/reports/FBgn0263780 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR001375 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001375, InterPro:IPR002469" - "CG17684, CG40072, CG40260" "IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR002469:Dipeptidylpeptidase IV, N-terminal domain, IPR029058:Alpha/Beta hydrolase fold" CG17684 11-Aug-17 DroID_v2017_08 "Drer\apeh, Drer\fap, Drer\zgc:136971, Drer\LOC101886435, Drer\dpp6a, Drer\LOC101883320, Drer\dpp4, Drer\dpp6b" "Scer\DAP2, Scer\STE13" "Cele\dpf-1, Cele\dpf-2" "Xtro\apeh, Xtro\dpp6, Xtro\dpp4, Xtro\dpp10" "Mmus\Apeh, Mmus\Fap, Mmus\Dpp6, Mmus\Dpp4, Mmus\Dpp10" "Hsap\DPP6, Hsap\FAP, Hsap\DPP10, Hsap\APEH, Hsap\DPP4" FBgn0030611 CG15027 - http://flybase.org/reports/FBgn0030611 protein_coding_gene - - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001000592 ribosome ; GO:0005840 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001000592 "BcDNA:SD22530, CG15027" IPR021346:Translation machinery-associated protein 16 CG15027 11-Aug-17 DroID_v2017_08 Drer\tma16 Scer\TMA16 - Xtro\tma16 Mmus\Tma16 Hsap\TMA16 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0047217 CR31456 - http://flybase.org/reports/FBgn0047217 non_protein_coding_gene - - - "BcDNA:LD10401, CR31456" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000395 cv-2 crossveinless 2 http://flybase.org/reports/FBgn0000395 FBgn0034625 protein_coding_gene BMP binding ; GO:0036122 | inferred from physical interaction with dpp inferred from physical interaction with gbb heparan sulfate proteoglycan binding ; GO:0043395 | inferred from genetic interaction with botv BMP receptor binding ; GO:0070700 | inferred from physical interaction with tkv endothelial cell differentiation ; GO:0045446 | inferred from electronic annotation with InterPro:IPR030120 negative regulation of BMP signaling pathway ; GO:0030514 | inferred from electronic annotation with InterPro:IPR030120 regulation of BMP signaling pathway ; GO:0030510 | inferred from genetic interaction with sog inferred from physical interaction with dpp inferred from physical interaction with tkv inferred from physical interaction with gbb imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cell surface ; GO:0009986 | inferred from direct assay "Cv2, Cv 2, cv 2, CT35855, CG15671, cv-2, BMPER, Cv-2, CV2" "IPR001007:VWFC domain, IPR001846:von Willebrand factor, type D domain, IPR014853:Uncharacterised domain, cysteine-rich, IPR030120:BMP-binding endothelial regulator protein" CG15671 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-283b1.7, Drer\muc5d, Drer\si:dkey-266m15.6, Drer\LOC100332723, Drer\vwc2, Drer\bmper, Drer\zgc:113531, Drer\vwc2l" - Cele\T01D3.6 "Xtro\kcp, Xtro\vwc2, Xtro\bmper, Xtro\vwc2l.2" "Mmus\Vwc2, Mmus\Bmper, Mmus\Vwc2l, Mmus\Fcgbp, Mmus\Chrdl2, Mmus\Kcp" "Hsap\FCGBP, Hsap\BMPER, Hsap\VWC2L, Hsap\VWC2, Hsap\CHRDL2, Hsap\KCP" "viable,partially lethal - majority die,cold sensitive,visible,dominant,recessive,lethal" "wing,wing vein,posterior crossvein,anterior crossvein,ectopic,posterior,crossvein" FBgn0083996 CG41354 - http://flybase.org/reports/FBgn0083996 protein_coding_gene - - - CG41354 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014304 l(3)neo14 lethal (3) neo14 http://flybase.org/reports/FBgn0014304 - gene - - - l(3)neo14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038422 CG14880 - http://flybase.org/reports/FBgn0038422 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14880 IPR002557:Chitin binding domain CG14880 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - FBgn0262454 mir-1007 mir-1007 stem loop http://flybase.org/reports/FBgn0262454 miRNA_gene - - - "dme-mir-1007, mir-1007, MIR-1007, CR43025, miR-1007" - CR43025 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0084002 CG41435 - http://flybase.org/reports/FBgn0084002 protein_coding_gene - - - CG41435 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010100 Acon Aconitase http://flybase.org/reports/FBgn0010100 "FBgn0010634, FBgn0032927, FBgn0043824" protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR006248 aconitate hydratase activity ; GO:0003994 | inferred from sequence or structural similarity aconitate hydratase activity ; GO:0003994 | non-traceable author statement aconitate hydratase activity ; GO:0003994 | inferred from sequence or structural similarity with UniProtKB:Q99798" tricarboxylic acid cycle ; GO:0006099 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q99798 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity "ACON-1, Acon, m-acon, i204, i59, CG9244, FBgn0010100, mAc, AconM, BEST:GH10550, l(2)07054, M-Acon, mAcon, hsp60, mACON, m-Acon, acon" "IPR015928:Aconitase/3-isopropylmalate dehydratase, swivel, IPR015931:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3, IPR015932:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2, IPR000573:Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, IPR001030:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain, IPR006248:Aconitase, mitochondrial-like, IPR018136:Aconitase family, 4Fe-4S cluster binding site" CG9244 11-Aug-17 DroID_v2017_08 Drer\aco2 "Scer\LEU1, Scer\ACO2, Scer\ACO1, Scer\LYS4, Scer\MRPL49" "Cele\aco-1, Cele\aco-2" Xtro\aco2 "Mmus\Ireb2, Mmus\Aco2, Mmus\Aco1" "Hsap\IREB2, Hsap\ACO1, Hsap\ACO2" "lethal - all die during embryonic stage,recessive,lethal,viable,partially lethal,short lived,locomotor behavior defective,increased cell death" "mitochondrionple.PF,embryonic/larval brain | larval stage" FBgn0001755 l(1)M3 lethal (1) M3 http://flybase.org/reports/FBgn0001755 - gene - - - l(1)M3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0044089 E(rst)D70 E(rst)D70 http://flybase.org/reports/FBgn0044089 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D70, E(rst)D70" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0051933 CG31933 - http://flybase.org/reports/FBgn0051933 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG15622, CG31933, gi22945479, gi21064045" "IPR004245:Protein of unknown function DUF229, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG31933 11-Aug-17 DroID_v2017_08 - - "Cele\T07G12.3, Cele\M03F8.5, Cele\Y73F8A.35, Cele\F15H10.7, Cele\Y38A10A.2, Cele\Y41E3.1, Cele\F32D8.2, Cele\F07C3.3, Cele\K03A11.4, Cele\R03G8.3, Cele\F32G8.2, Cele\F10C2.3, Cele\R03G8.1, Cele\T23E1.1" - - - viable FBgn0024705 anon-84Ac anon-84Ac http://flybase.org/reports/FBgn0024705 - gene - - - anon-84Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035750 CG14826 - http://flybase.org/reports/FBgn0035750 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14826 IPR006631:Protein of unknown function DM4/12 CG14826 11-Aug-17 DroID_v2017_08 - - - - - - DRSC10197 E 0.468503888 0.018254562 1.552314443 0.424096142 0.637877435 0.918861889 FBgn0015731 Fip2 Ftz-interacting protein 2 http://flybase.org/reports/FBgn0015731 - gene - regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay - "FIP2, Fip2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040023 CG12575 - http://flybase.org/reports/FBgn0040023 protein_coding_gene - - - CG12575 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058120 CG40120 - http://flybase.org/reports/FBgn0058120 protein_coding_gene - - - CG40120 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21163 K 0.548618458 -0.037047855 -0.388348983 0.633041696 1.068674376 1.528002912 FBgn0038547 CG17803 - http://flybase.org/reports/FBgn0038547 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG17803 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG17803 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-262g12.7, Drer\znf1070, Drer\LOC100537572, Drer\zbtb39, Drer\LOC100538201, Drer\LOC100536312, Drer\znf687a, Drer\znf1078, Drer\znf1069, Drer\LOC100333583, Drer\si:ch73-266f23.3, Drer\si:dkeyp-53d3.5, Drer\LOC100537450, Drer\si:dkey-217d24.6, Drer\znf1159, Drer\LOC100537891, Drer\zgc:113135, Drer\znf1072, Drer\prdm2a, Drer\znf1177, Drer\zgc:173714, Drer\si:dkey-1b17.5, Drer\si:ch211-255f4.1, Drer\LOC100534892, Drer\LOC101883642, Drer\znf407, Drer\znf1073, Drer\LOC100537066, Drer\zgc:174703, Drer\LOC100149007, Drer\LOC108179202, Drer\LOC108184006, Drer\zgc:162948, Drer\znf995, Drer\prdm2b, Drer\zgc:173624, Drer\znf592, Drer\znf1053, Drer\LOC103910931, Drer\LOC100537431, Drer\mynn, Drer\si:dkey-30f3.2, Drer\si:dkey-237m9.1, Drer\si:ch211-226o13.2, Drer\znf1079, Drer\LOC100534765, Drer\LOC100536110, Drer\LOC569391, Drer\znf1077, Drer\zgc:174704, Drer\gb:am422109, Drer\znf408, Drer\LOC100536900, Drer\znf644a, Drer\LOC108182424, Drer\si:ch211-212k5.4, Drer\si:dkeyp-35e5.9, Drer\hnrnpa0l, Drer\si:dkey-7i4.5, Drer\LOC100536649, Drer\znf1167, Drer\znf644b, Drer\si:dkey-20i20.2, Drer\znf687b, Drer\znf569l, Drer\LOC100333857, Drer\LOC100150619, Drer\zgc:174314, Drer\si:ch211-255f4.3, Drer\LOC101882607, Drer\LOC100149645, Drer\znf1043, Drer\zbtb17, Drer\zgc:173713, Drer\znf1147, Drer\znf1041, Drer\znf1171, Drer\znf1040, Drer\znf319, Drer\LOC108183429, Drer\LOC100332458, Drer\zbtb41, Drer\znf1059, Drer\znf1068, Drer\znf507, Drer\znf1173, Drer\LOC103910994, Drer\si:dkeyp-104f11.6, Drer\si:ch211-194b1.1, Drer\zgc:173716, Drer\zgc:174315, Drer\znf1181, Drer\zgc:173705, Drer\LOC100537352, Drer\LOC101882787, Drer\LOC101885193, Drer\LOC101882721, Drer\LOC100329723, Drer\LOC100535113, Drer\prdm4, Drer\zgc:174696, Drer\si:dkeyp-35e5.10, Drer\LOC108183430, Drer\LOC101885678, Drer\si:ch211-162i8.2, Drer\si:ch211-223a21.4" Scer\AZF1 "Cele\lin-29, Cele\C27A12.2, Cele\Y53H1A.2, Cele\M03D4.4, Cele\zfp-2, Cele\K11D2.4, Cele\Y55F3AM.14, Cele\ztf-3, Cele\klu-1, Cele\F58G1.2" - "Mmus\4930522L14Rik, Mmus\Zfp951, Mmus\Zfp746, Mmus\Zfp777, Mmus\Zfp398, Mmus\Zfp820, Mmus\Zbtb41, Mmus\Zfp758, Mmus\Zfp946, Mmus\Zfp644, Mmus\Zfp867, Mmus\Zfp868, Mmus\Zfp408, Mmus\Zfp120, Mmus\Zfp108, Mmus\Zfp786, Mmus\AU041133, Mmus\Zfp944, Mmus\Zfp407, Mmus\Zfp984, Mmus\Zfp429, Mmus\Zfp426, Mmus\Zkscan7, Mmus\Zfp61, Mmus\Gm20939, Mmus\Zfp872, Mmus\Zbtb39, Mmus\Zfp942, Mmus\Zfp472, Mmus\Zfp960, Mmus\Zfp563, Mmus\Zfp287, Mmus\Zbtb17, Mmus\Zfp981, Mmus\Zfp467, Mmus\Zfp985, Mmus\Prdm4, Mmus\Prdm2, Mmus\Zfp507, Mmus\Zfp109, Mmus\Zfp646, Mmus\Zfp870, Mmus\Zfp534, Mmus\Zfp932, Mmus\Zfp982, Mmus\Gm4767, Mmus\Zfp57, Mmus\Gzf1, Mmus\Gm10778, Mmus\Zfp784, Mmus\Zfp992, Mmus\Zfp987, Mmus\Zfp592, Mmus\Zfp943, Mmus\Gm14432, Mmus\Zfp114, Mmus\Zfp947, Mmus\Zfp445, Mmus\Zfp866, Mmus\Zfp697, Mmus\Zfp768, Mmus\Zfp871, Mmus\Zfp687, Mmus\Zfp980, Mmus\Zfp93, Mmus\Zfp979, Mmus\Zfp597, Mmus\Rex2, Mmus\Zfp991, Mmus\Zfp94, Mmus\Zfp97, Mmus\Zfp319, Mmus\Zfp462, Mmus\Zfp995, Mmus\Rsl1, Mmus\Mynn" "Hsap\ZNF136, Hsap\ZNF646, Hsap\ZNF527, Hsap\ZBTB41, Hsap\GZF1, Hsap\ZFP57, Hsap\PRDM2, Hsap\ZBTB17, Hsap\ZNF786, Hsap\ZNF426, Hsap\PRDM4, Hsap\ZNF547, Hsap\ZNF398, Hsap\ZNF530, Hsap\ZNF507, Hsap\ZNF333, Hsap\ZNF230, Hsap\ZNF462, Hsap\ZNF776, Hsap\ZNF416, Hsap\ZNF287, Hsap\ZNF697, Hsap\ZNF17, Hsap\ZNF407, Hsap\ZNF587, Hsap\ZNF592, Hsap\ZNF852, Hsap\ZNF34, Hsap\ZNF155, Hsap\ZNF597, Hsap\ZNF467, Hsap\ZNF644, Hsap\ZNF774, Hsap\ZNF746, Hsap\ZNF8, Hsap\ZNF670, Hsap\ZNF445, Hsap\MYNN, Hsap\ZNF687, Hsap\ZNF806, Hsap\ZNF417, Hsap\ZKSCAN7, Hsap\ZNF768, Hsap\ZNF777, Hsap\ZBTB39, Hsap\ZNF408, Hsap\ZNF285, Hsap\ZNF707, Hsap\ZNF222, Hsap\ZNF223, Hsap\ZNF319, Hsap\ZNF281, Hsap\ZNF784, Hsap\ZNF214" viable DRSC22811 E 0.062826746 0.126168717 -0.893777183 -2.651257869 0.626585416 0.745671747 FBgn0263091 CR43359 - http://flybase.org/reports/FBgn0263091 pseudogene_attribute - - - CR43359 - CR43359 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000374 cripC crippled C http://flybase.org/reports/FBgn0000374 - gene - - - cripC - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,uncoordinated" leg FBgn0035160 hng3 hinge3 http://flybase.org/reports/FBgn0035160 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 basal RNA polymerase II transcription machinery binding ; GO:0001099 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 "anon-WO0118547.557, CG13897, hng3" "IPR004210:BESS motif, IPR006578:MADF domain" CG13897 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-207i20.3, Drer\zgc:152938" - "Cele\madf-3, Cele\madf-4, Cele\madf-9" - - - "flightless,viable" wing hinge FBgn0014102 anon-4Ca anon-4Ca http://flybase.org/reports/FBgn0014102 - gene - - - "T3, anon-4Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult head

FBgn0265975 hbs::sns - http://flybase.org/reports/FBgn0265975 engineered_fusion_gene - - - hbs::sns - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041586 mei-217::mei-218 mei-217::mei-218 http://flybase.org/reports/FBgn0041586 engineered_fusion_gene - - - mei-217::mei-218 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267656 CR45994 - http://flybase.org/reports/FBgn0267656 non_protein_coding_gene - - - CR45994 - CR45994 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035529 Fdx2 Ferredoxin 2 http://flybase.org/reports/FBgn0035529 protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR001055, InterPro:IPR018298 electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with UniProtKB:P10109" positive regulation of ecdysteroid biosynthetic process ; GO:0045998 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P10109 "BcDNA:RH09920, BcDNA:RE08888, CG1319, Fdx2, Fdxh2" "IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR001055:Adrenodoxin, IPR012675:Beta-grasp domain, IPR018298:Adrenodoxin, iron-sulphur binding site" CG1319 11-Aug-17 DroID_v2017_08 "Drer\fdx1b, Drer\fdx1, Drer\cox15, Drer\fdx1l" "Scer\COX15, Scer\YAH1" "Cele\cox-15, Cele\Y73F8A.27" "Xtro\fdx1, Xtro\fdx1l, Xtro\LOC100498263" "Mmus\Fdx1, Mmus\Fdx1l, Mmus\Cox15" "Hsap\FDX1L, Hsap\FDX1, Hsap\COX15" "viable,visible" trichogen cell FBgn0037552 CG7800 - http://flybase.org/reports/FBgn0037552 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CT23295, CG7800" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG7800 11-Aug-17 DroID_v2017_08 Drer\tlr8b - Cele\let-4 - Mmus\Tlr3 Hsap\TLR3 viable FBgn0029830 Grip Glutamate receptor binding protein http://flybase.org/reports/FBgn0029830 protein_coding_gene guanylate kinase activity ; GO:0004385 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 protein binding ; GO:0005515 | inferred from physical interaction with ed receptor binding ; GO:0005102 | inferred from physical interaction with fz2 ionotropic glutamate receptor binding ; GO:0035255 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 protein binding ; GO:0005515 | inferred from physical interaction with kon "protein import into nucleus, translocation ; GO:0000060 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype determination of muscle attachment site ; GO:0016204 | inferred from mutant phenotype receptor localization to synapse ; GO:0097120 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 chemical synaptic transmission ; GO:0007268 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 nervous system development ; GO:0007399 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype inferred from genetic interaction with if inferred from genetic interaction with mew inferred from genetic interaction with kon receptor clustering ; GO:0043113 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from biological aspect of ancestor with PANTHER:PTN001501163" Golgi-associated vesicle ; GO:0005798 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay postsynaptic density ; GO:0014069 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 ionotropic glutamate receptor complex ; GO:0008328 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001501163 basolateral plasma membrane ; GO:0016323 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 neuromuscular junction ; GO:0031594 | inferred from direct assay postsynaptic membrane ; GO:0045211 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 "DGrip, grip, CG14447, CG5980, dgrip, Grip, dGRIP, Dgrip, GRIP" IPR001478:PDZ domain CG14447 11-Aug-17 DroID_v2017_08 "Drer\grid2ipa, Drer\pard3bb, Drer\grip2a, Drer\dlg5a, Drer\ptpn21, Drer\slc9a3r1, Drer\il16, Drer\dlg1l, Drer\dlg4b, Drer\si:dkey-92i15.4, Drer\dlg1, Drer\ptpn13, Drer\grip1, Drer\lnx1, Drer\inadl, Drer\pdzd7b, Drer\frmpd2, Drer\grip2b" - "Cele\dlg-1, Cele\F23C8.13" "Xtro\grid2ip, Xtro\dlg5, Xtro\grip2, Xtro\lnx1, Xtro\ptpn13, Xtro\grip1, Xtro\ptpn14" "Mmus\Dlg5, Mmus\Dlg1, Mmus\Pdzd2, Mmus\Ush1c, Mmus\Grid2ip, Mmus\Grip2, Mmus\Patj, Mmus\Il16, Mmus\Lnx1, Mmus\Mpdz, Mmus\Dlg4, Mmus\Grasp, Mmus\Ptpn21, Mmus\Ptpn13, Mmus\Ptpn14, Mmus\Pdzd11, Mmus\Grip1, Mmus\Pdzph1" "Hsap\DLG5, Hsap\PDZD2, Hsap\MPDZ, Hsap\GRASP, Hsap\PATJ, Hsap\GRIP1, Hsap\IL16, Hsap\GRIP2, Hsap\DLG4, Hsap\GRID2IP, Hsap\PTPN21, Hsap\LNX1, Hsap\FRMPD2, Hsap\PARD3B, Hsap\PTPN13, Hsap\USH1C, Hsap\DLG1, Hsap\PTPN14" "wild-type,neuroanatomy defective,viable,lethal" "ventral longitudinal muscle,adult abdomen,adult head,A1-7 ventral longitudinal muscle 1,precursor,muscle system,embryonic/larval somatic muscle,embryonic somatic muscle,lateral transverse muscle,abdominal 1 dorsal oblique muscle 5,abdominal 2 dorsal oblique muscle 5,abdominal 3 dorsal oblique muscle 5,abdominal 4 dorsal oblique muscle 5,abdominal 5 dorsal oblique muscle 5,abdominal 6 dorsal oblique muscle 5,abdominal 7 dorsal oblique muscle 5,bouton,presynaptic active zoneC164" FBgn0053061 CG33061 - http://flybase.org/reports/FBgn0053061 protein_coding_gene calcium-activated potassium channel activity ; GO:0015269 | inferred from biological aspect of ancestor with PANTHER:PTN000278842 monovalent inorganic cation transport ; GO:0015672 | inferred from electronic annotation with InterPro:IPR007866 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR007866 "CG13057, CG33061" IPR007866:TRIC channel CG33061 11-Aug-17 DroID_v2017_08 "Drer\tmem38b, Drer\tmem38a" - "Cele\Y57A10A.28, Cele\Y57A10A.10" "Xtro\tmem38b, Xtro\tmem38a" "Mmus\Tmem38a, Mmus\Tmem38b" "Hsap\TMEM38B, Hsap\TMEM38A" FBgn0083258 E(smoDN)918 Enhancer of smoDN 918 http://flybase.org/reports/FBgn0083258 gene - - - E(smoDN)918 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085558 CG41027 - http://flybase.org/reports/FBgn0085558 protein_coding_gene - - - CG41027 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058295 CG40295 - http://flybase.org/reports/FBgn0058295 protein_coding_gene - - - CG40295 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053445 5SrRNA:CR33445 5SrRNA:CR33445 http://flybase.org/reports/FBgn0053445 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33445, 5SrRNA:CR33445" - CR33445 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013813 Dhc98D Dynein heavy chain at 89D http://flybase.org/reports/FBgn0013813 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity inner dynein arm ; GO:0036156 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 "Dhc98D, CG1842, dhc, DHC, Dhc, DHC6" "IPR004273:Dynein heavy chain domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026982:Dynein-1-alpha heavy chain, flagellar inner arm I1 complex, IPR026983:Dynein heavy chain, IPR003593:AAA+ ATPase domain, IPR011704:ATPase, dynein-related, AAA domain" CG1842 11-Aug-17 DroID_v2017_08 "Drer\dnah2, Drer\dnah12, Drer\dnah7, Drer\dync1h1, Drer\dnah7l, Drer\dnah1, Drer\wu:fj30b09, Drer\si:dkeyp-86b9.1, Drer\dnah3, Drer\si:dkeyp-87a6.1, Drer\dnah9l" Scer\DYN1 Cele\che-3 "Xtro\dnah14, Xtro\dnah2, Xtro\dnah10, Xtro\dnah7" "Mmus\Dnhd1, Mmus\Dnah11, Mmus\Dnah9, Mmus\Dnah3, Mmus\Dnah5, Mmus\Dync2h1, Mmus\Dnah14, Mmus\Dnah7b, Mmus\Dnah1, Mmus\Dnah12, Mmus\Dync1h1, Mmus\Dnah2, Mmus\Dnah7a, Mmus\Dnah10, Mmus\Dnah17, Mmus\Dnah8, Mmus\Dnah6" "Hsap\DNAH8, Hsap\DNAH5, Hsap\DNAH9, Hsap\DNAH11, Hsap\DNAH1, Hsap\DNAH7, Hsap\DNAH2, Hsap\DNAH10, Hsap\CCDC88B, Hsap\DYNC1H1, Hsap\DNAH6, Hsap\DNAH14, Hsap\DNAH3, Hsap\DNHD1, Hsap\DNAH12, Hsap\DNAH17, Hsap\DYNC2H1" " adult stage | female , embryonic stage , adult stage | male " testis

FBgn0019736 l(1)98B lethal (1) 98B http://flybase.org/reports/FBgn0019736 - gene - - - l(1)98B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058413 CG40413 - http://flybase.org/reports/FBgn0058413 protein_coding_gene - - - CG40413 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031528 CG15412 - http://flybase.org/reports/FBgn0031528 protein_coding_gene - - - CG15412 "IPR032675:Leucine-rich repeat domain, L domain-like" CG15412 11-Aug-17 DroID_v2017_08 Drer\si:ch211-214j8.12 - - - - - viable FBgn0004421 gustA gustatory-defective A http://flybase.org/reports/FBgn0004421 "FBgn0001154, FBgn0001158" gene - - - "gust-A, gust[x2], gust[x1], gustA" - - 11-Aug-17 DroID_v2017_08 - - - - - - taste perception defective labellar taste bristle FBgn0083988 snoRNA:Me28S-C3420a snoRNA:Me28S-C3420a http://flybase.org/reports/FBgn0083988 snoRNA_gene - - - "CR34152, snoRNA:Me28S-C3420a, Me28S-C3420a" - CR34152 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267157 CR45597 - http://flybase.org/reports/FBgn0267157 non_protein_coding_gene - - - CR45597 - CR45597 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266766 CR45231 - http://flybase.org/reports/FBgn0266766 non_protein_coding_gene - - - CR45231 - CR45231 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263578 mir-4916 mir-4916 stem loop http://flybase.org/reports/FBgn0263578 miRNA_gene - - - "mir-4916, dme-mir-4916, CR43563" - CR43563 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036656 CG13026 - http://flybase.org/reports/FBgn0036656 protein_coding_gene - - - CG13026 - CG13026 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039306 RIOK2 RIO kinase 2 http://flybase.org/reports/FBgn0039306 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR015285, InterPro:IPR018935 protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR015285, InterPro:IPR018935 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with SGD:S000005151" protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR015285 cellular response to starvation ; GO:0009267 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype positive regulation of glial cell proliferation ; GO:0060252 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005151 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005151 "CG11859, RIOK2, dRIOK2, Rio2" "IPR011009:Protein kinase-like domain, IPR018935:RIO kinase, conserved site, IPR015285:RIO2 kinase winged helix domain, N-terminal, IPR030484:Serine/threonine-protein kinase Rio2, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR000687:RIO kinase" CG11859 11-Aug-17 DroID_v2017_08 Drer\riok2 Scer\RIO2 Cele\riok-2 Xtro\riok2 Mmus\Riok2 Hsap\RIOK2 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0028687 Rpt1 Regulatory particle triple-A ATPase 1 http://flybase.org/reports/FBgn0028687 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ATPase activity ; GO:0016887 | inferred from sequence model" positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9548 inferred from direct assay cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000001628 polytene chromosome ; GO:0005700 | inferred from direct assay" "p48B, dRpt1, Dm_Rpt1, l(2)43Ed, l(2)05643, Dmp48B, CG1341, anon-WO0118547.90, Rpt1, 1341, S7, Q7KMQ0_DROME" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1341 11-Aug-17 DroID_v2017_08 "Drer\wdr12, Drer\psmc6, Drer\psmc5, Drer\psmc2" Scer\RPT1 "Cele\rpt-6, Cele\rpt-4, Cele\rpt-1, Cele\F56F11.4" "Xtro\psmc5, Xtro\wdr12, Xtro\psmc6, Xtro\psmc2" "Mmus\Psmc6, Mmus\Psmc5, Mmus\Psmc2, Mmus\Wdr12" "Hsap\WDR12, Hsap\PSMC2, Hsap\PSMC5, Hsap\PSMC6" "lethal,recessive,neuroanatomy defective,lethal - all die during pupal stage" "intersegmental nerve,anterior fascicle & synapse" DRSC07542 IEK -3.340207102 -4.040886236 -2.245228358 -1.656881804 7.184191381 -1.702103651 FBgn0001704 l(1)ESHS25 lethal (1) ESHS25 http://flybase.org/reports/FBgn0001704 - gene - - - l(1)ESHS25 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046696 RNaseP:RNA Ribonuclease P RNA http://flybase.org/reports/FBgn0046696 non_protein_coding_gene - - - "CR32868, RNaseP:RNA, RNase P RNA, P RNA, RNAseP, chr3R:27043287..27043402, RPR RNA" - CR32868 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003599 Su(var)3-8 Suppressor of variegation 3-8 http://flybase.org/reports/FBgn0003599 - gene - - - "Su-var(3)8, Su(var)3-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant,heat sensitive,female sterile" FBgn0000795 fs(1)de6 female sterile (1) defective eggs 6 http://flybase.org/reports/FBgn0000795 - gene - - - "de6, fs(1)de6" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "dorsal appendage,chorion,endochorion" FBgn0050374 CR30374 - http://flybase.org/reports/FBgn0050374 pseudogene_attribute - - - "CR30374, CG30374" - CR30374 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036796 CG18231 - http://flybase.org/reports/FBgn0036796 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 CG18231 "IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain" CG18231 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\p4ha2, Drer\p4htm, Drer\zgc:158254, Drer\p4ha1a, Drer\zgc:152670, Drer\p4ha3" - "Cele\Y43F8B.19, Cele\phy-4, Cele\phy-2, Cele\C14E2.4, Cele\phy-3" "Xtro\p4ha2, Xtro\p4ha3, Xtro\p4ha1" "Mmus\P4ha1, Mmus\P4ha2, Mmus\P4htm, Mmus\P4ha3" "Hsap\P4HA2, Hsap\P4HA3, Hsap\P4HA1, Hsap\P4HTM" "viable,fertile" FBgn0260225 CR42499 - http://flybase.org/reports/FBgn0260225 pseudogene_attribute - - - "CR42499, CG42499" - CR42499 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038007 Cyp313a3 Cyp313a3 http://flybase.org/reports/FBgn0038007 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "313a3, CG10093, Cyp313a3, CYP313a3" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10093 11-Aug-17 DroID_v2017_08 "Drer\cyp4v7, Drer\zgc:123299, Drer\cyp26c1, Drer\cyp19a1a, Drer\cyp20a1, Drer\cyp46a1.1, Drer\cyp26a1, Drer\cyp46a1.3, Drer\cyp46a1.2, Drer\cyp4v8, Drer\cyp4t8, Drer\LOC100329425, Drer\cyp4f3, Drer\cyp26b1, Drer\cyp19a1b, Drer\cyp46a1.4" "Scer\DIT2, Scer\ERG11, Scer\ERG5" "Cele\cyp-29A3, Cele\cyp-29A4" "Xtro\cyp4v2, Xtro\cyp4b1, Xtro\cyp19a1, Xtro\mgc108213, Xtro\cyp4f22, Xtro\cyp20a1, Xtro\cyp4f2, Xtro\cyp26c1, Xtro\LOC100488227, Xtro\cyp4b1.2, Xtro\LOC100487918, Xtro\cyp26a1, Xtro\cyp26b1" "Mmus\Cyp4f18, Mmus\Cyp26a1, Mmus\Cyp4f16, Mmus\Cyp4a12a, Mmus\Cyp4b1, Mmus\Cyp4v3, Mmus\Cyp4a32, Mmus\Cyp4x1, Mmus\Cyp19a1, Mmus\Cyp4a10, Mmus\Cyp4f40, Mmus\Cyp4f17, Mmus\Cyp4f15, Mmus\Cyp4a14, Mmus\Cyp46a1, Mmus\Cyp4f37, Mmus\Cyp4f14, Mmus\Cyp4a31, Mmus\Cyp4a12b, Mmus\Cyp20a1, Mmus\Cyp26b1, Mmus\Cyp4f39, Mmus\Cyp4f13, Mmus\Cyp26c1" "Hsap\CYP4V2, Hsap\CYP4F12, Hsap\CYP4F2, Hsap\CYP4F3, Hsap\CYP4A11, Hsap\CYP4X1, Hsap\CYP26C1, Hsap\CYP26A1, Hsap\CYP19A1, Hsap\CYP26B1, Hsap\CYP46A1, Hsap\CYP4B1, Hsap\CYP20A1, Hsap\CYP4F22, Hsap\CYP4A22, Hsap\CYP4F11, Hsap\CYP4Z1" viable FBgn0043546 anon-AE002656.1 anon-AE002656.1 http://flybase.org/reports/FBgn0043546 gene - - - anon-AE002656.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013596 l(3)B12-3-31 lethal (3) B12-3-31 http://flybase.org/reports/FBgn0013596 - gene - - - l(3)B12-3-31 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266021 CR44786 - http://flybase.org/reports/FBgn0266021 non_protein_coding_gene - - - "CR44786, lincRNA.219" - CR44786 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067053 R19 R19 http://flybase.org/reports/FBgn0067053 gene - - - R19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die" FBgn0060678 l(3)S077009b lethal (3) S077009b http://flybase.org/reports/FBgn0060678 gene - - - "0770/09, l(3)S077009b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0045485 Gr36c Gustatory receptor 36c http://flybase.org/reports/FBgn0045485 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr36B.3, CG15137, Gr36B3, CG31748, Gr36c, GR36c" IPR013604:7TM chemoreceptor CG31748 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - viable FBgn0264084 CR43753 - http://flybase.org/reports/FBgn0264084 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "CR43753, lincRNA.13" - CR43753 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266597 ewg::Dvir\ewg - http://flybase.org/reports/FBgn0266597 engineered_fusion_gene - - - ewg::Dvir\ewg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265312 CR44285 - http://flybase.org/reports/FBgn0265312 non_protein_coding_gene - - - CR44285 - CR44285 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002389 l(3)93Df lethal (3) 93Df http://flybase.org/reports/FBgn0002389 - gene - - - "er19, l(3)er19, l(3)93Df" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,locomotor behavior defective" wing FBgn0037819 CG14688 - http://flybase.org/reports/FBgn0037819 protein_coding_gene phytanoyl-CoA dioxygenase activity ; GO:0048244 | inferred from sequence or structural similarity with HGNC:8940 fatty acid alpha-oxidation ; GO:0001561 | inferred from sequence or structural similarity with HGNC:8940 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8940 CG14688 IPR008775:Phytanoyl-CoA dioxygenase CG14688 11-Aug-17 DroID_v2017_08 Drer\phyhd1 - Cele\Y105C5B.9 "Xtro\phyhd1, Xtro\phyh" Mmus\Phyhd1 Hsap\PHYHD1 viable DRSC14911 I 1.715365879 1.487000648 0.35860784 0.592337658 -0.91082243 -0.422674427 FBgn0264493 rdx roadkill http://flybase.org/reports/FBgn0264493 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P19538 inferred from physical interaction with UniProtKB:Q9V475 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with ci eye morphogenesis ; GO:0048592 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype negative regulation of protein import into nucleus ; GO:0042308 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from genetic interaction with egr protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 segment polarity determination ; GO:0007367 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 eye development ; GO:0001654 | inferred from mutant phenotype protein destabilization ; GO:0031648 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "rdx, CG9924, Rdx, SPOP, hib, HIB, mei-P19, l(3)03477, l(3)2004, l(3)88Aa, l(3)A6, l(3)SG40, l(3)dsl6, l(3)j1D1, l(3)j4C7, l(3)dsl-6, CG12537, Dromel_CG9924_FBtr0082871_rdx_mORF, D-SPOP, Spop, anon-WO0118547.577, BEST:GM07940, CG10235, 0869/09, l(3)S086909, Hib" "IPR034089:SPOP, C-terminal BACK-like domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000210:BTB/POZ domain, IPR002083:MATH/TRAF domain, IPR008974:TRAF-like, IPR011333:SKP1/BTB/POZ domain" CG12537 11-Aug-17 DroID_v2017_08 "Drer\spopla, Drer\spoplb, Drer\spop, Drer\klhl11, Drer\kbtbd4" Scer\YIL001W "Cele\bath-42, Cele\math-25, Cele\bath-43, Cele\btb-5, Cele\btb-14, Cele\btb-13, Cele\btb-7, Cele\math-21, Cele\R10E4.1, Cele\math-50, Cele\btb-20, Cele\hpo-9, Cele\math-10, Cele\btb-6, Cele\Y59E9AL.8, Cele\mel-26, Cele\btb-17, Cele\btb-16, Cele\bath-30, Cele\btb-18, Cele\bath-40, Cele\btb-19, Cele\btb-11, Cele\btb-12, Cele\btb-9" Xtro\spop "Mmus\Tdpoz1, Mmus\Klhl11, Mmus\Tdpoz2, Mmus\Tdpoz5, Mmus\Tdpoz4, Mmus\Kbtbd4, Mmus\Gm10696, Mmus\Gm10697, Mmus\Gm4858, Mmus\Gm9125, Mmus\Spop, Mmus\Spopl, Mmus\Tdpoz3" "Hsap\SPOPL, Hsap\KLHL11, Hsap\SPOP, Hsap\KBTBD4" DRSC16580 I 1.855874998 -0.122935647 0.146086333 0.250765959 -0.58438681 -0.203533946 FBgn0039988 CG12555 - http://flybase.org/reports/FBgn0039988 protein_coding_gene - - - CG12555 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039896 yellow-h yellow-h http://flybase.org/reports/FBgn0039896 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG1629, yellow-h, yell-h, h" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG1629 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\T27A1.3, Cele\F49E11.8, Cele\fbxa-76, Cele\C24H12.1" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 viable FBgn0029713 CG11436 - http://flybase.org/reports/FBgn0029713 protein_coding_gene molecular_function ; GO:0003674 | no biological data available actin filament polymerization ; GO:0030041 | inferred from biological aspect of ancestor with PANTHER:PTN001043092 actin cytoskeleton ; GO:0015629 | inferred from biological aspect of ancestor with PANTHER:PTN001043092 CG11436 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG11436 11-Aug-17 DroID_v2017_08 Drer\ttc17 - Cele\T19A5.1 Xtro\ttc17 Mmus\Ttc17 Hsap\TTC17 FBgn0051690 CG31690 - http://flybase.org/reports/FBgn0051690 protein_coding_gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15397, CG11542, CG31690" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR013618:Domain of unknown function DUF1736, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1" CG31690 11-Aug-17 DroID_v2017_08 "Drer\ttc25, Drer\kdm6ba, Drer\kdm6a, Drer\ifit9, Drer\ogt.2, Drer\bbs4, Drer\spag1b, Drer\spag1a, Drer\ifit15, Drer\ifit8, Drer\dyx1c1, Drer\ifit14, Drer\tmtc2b, Drer\ifit16, Drer\tomm34, Drer\ogt.1, Drer\tmtc2a, Drer\fkbpl, Drer\kdm6al, Drer\ttc6, Drer\tmtc3" "Scer\SWA2, Scer\TAH1, Scer\CYC8" Cele\F32D1.3 "Xtro\tmtc2, Xtro\tmtc3, Xtro\ifit5, Xtro\kdm6b, Xtro\ttc16, Xtro\bbs4, Xtro\ttc25, Xtro\spag1, Xtro\ogt, Xtro\kdm6a, Xtro\dyx1c1" "Mmus\Fkbpl, Mmus\Spag1, Mmus\Bbs4, Mmus\Ttc25, Mmus\Kdm6b, Mmus\Ifit1, Mmus\Ifit3b, Mmus\Tmtc2, Mmus\Dyx1c1, Mmus\Lonrf3, Mmus\Ifit1bl2, Mmus\Tmtc1, Mmus\Ifit3, Mmus\Ttc16, Mmus\Ogt, Mmus\Kdm6a, Mmus\Uty, Mmus\Tmtc3, Mmus\Tomm34, Mmus\Ifit1bl1, Mmus\Ttc24, Mmus\Ifit2" "Hsap\TMTC2, Hsap\BBS4, Hsap\TMTC1, Hsap\KDM6A, Hsap\UTY, Hsap\LONRF3, Hsap\IFIT1, Hsap\IFIT5, Hsap\TMTC3, Hsap\TTC32, Hsap\TTC6, Hsap\IFIT1B, Hsap\KDM6B, Hsap\TTC24, Hsap\OGT, Hsap\SPAG1, Hsap\DYX1C1, Hsap\TOMM34, Hsap\IFIT2, Hsap\IFIT3, Hsap\FKBPL, Hsap\TTC16, Hsap\LONRF2" "viable,fertile" FBgn0259565 B2019 - http://flybase.org/reports/FBgn0259565 gene - - - B2019 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0030695 PGRP-LE Peptidoglycan recognition protein LE http://flybase.org/reports/FBgn0030695 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | traceable author statement peptidoglycan binding ; GO:0042834 | non-traceable author statement N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues peptidoglycan receptor activity ; GO:0016019 | traceable author statement peptidoglycan receptor activity ; GO:0016019 | non-traceable author statement peptidoglycan receptor activity ; GO:0016019 | inferred from sequence or structural similarity with UniProtKB:O76537 protein binding ; GO:0005515 | inferred from physical interaction with pirk peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b signal transduction ; GO:0007165 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | NOT inferred from mutant phenotype inferred from genetic interaction with Rel inferred from genetic interaction with Tak1 inferred from genetic interaction with Fadd innate immune response ; GO:0045087 | non-traceable author statement positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from direct assay peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement immune response ; GO:0006955 | traceable author statement defense response to bacterium ; GO:0042742 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "PGRP-LE, pgrp-le, CG8995, anon-WO0153538.66, PGRP, pgrp le" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein" CG8995 11-Aug-17 DroID_v2017_08 "Drer\pglyrp5, Drer\pglyrp2, Drer\pglyrp6" - - "Xtro\pglyrp2, Xtro\pglyrp1, Xtro\pglyrp1" "Mmus\Pglyrp1, Mmus\Pglyrp3, Mmus\Pglyrp4, Mmus\Pglyrp2" "Hsap\PGLYRP4, Hsap\PGLYRP1, Hsap\PGLYRP2, Hsap\PGLYRP3" "melanotic mass phenotype,heat sensitive,lethal,fertile,viable,immune response defective,short lived" "melanotic mass,heat sensitive,adult cuticle" FBgn0031107 HERC2 HECT and RLD domain containing protein 2 http://flybase.org/reports/FBgn0031107 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR010606 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:4868 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:4868 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:4868 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:4868 "HERC2, CG11734, dHERC2, AF189221.1" "IPR015940:Ubiquitin-associated domain, IPR000408:Regulator of chromosome condensation, RCC1, IPR000569:HECT domain, IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR010606:Mib-herc2, IPR008979:Galactose-binding domain-like, IPR004939:APC10/DOC domain, IPR021097:CPH domain, IPR009060:UBA-like, IPR014722:Ribosomal protein L2 domain 2" CG11734 11-Aug-17 DroID_v2017_08 "Drer\ftr97, Drer\rpgra, Drer\sergef, Drer\huwe1, Drer\herc1, Drer\rcc1, Drer\als2b, Drer\arel1, Drer\wbscr16, Drer\herc2, Drer\als2a, Drer\hace1, Drer\rccd1, Drer\rpgrb, Drer\rcbtb2, Drer\rcbtb1" "Scer\ATS1, Scer\SRM1, Scer\HUL4, Scer\FMP25" - "Xtro\als2cl, Xtro\herc1, Xtro\wbscr16, Xtro\nek9, Xtro\rcc1, Xtro\hectd3, Xtro\als2, Xtro\rcbtb1, Xtro\rcbtb2, Xtro\arel1, Xtro\herc2, Xtro\hace1" "Mmus\Rcc1, Mmus\Herc1, Mmus\Huwe1, Mmus\Gm15800, Mmus\Wbscr16, Mmus\Nek9, Mmus\Herc2, Mmus\Rcbtb2, Mmus\Rccd1, Mmus\Als2, Mmus\Rpgr, Mmus\Arel1, Mmus\Hace1, Mmus\Sergef, Mmus\Rcbtb1, Mmus\Hectd3" "Hsap\RCC1L, Hsap\RPGR, Hsap\HECTD3, Hsap\RCC1, Hsap\HACE1, Hsap\RCBTB1, Hsap\SERGEF, Hsap\HUWE1, Hsap\ALS2, Hsap\AREL1, Hsap\NEK9, Hsap\RCCD1, Hsap\HERC1, Hsap\RCBTB2, Hsap\HERC2, Hsap\HECTD4" viable FBgn0010265 RpS13 Ribosomal protein S13 http://flybase.org/reports/FBgn0010265 FBgn0021990 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement small ribosomal subunit rRNA binding ; GO:0070181 | inferred from biological aspect of ancestor with PANTHER:PTN000223267 "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000589, InterPro:IPR012606 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement" cytosolic ribosome ; GO:0022626 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "M(2)32A, S13, M(2)32, l(2)k09614, Rp17, CG13389, RpS13, M(2)29B, RPS13, Rp S13, Rps 13" "IPR000589:Ribosomal protein S15, IPR009068:S15/NS1, RNA-binding, IPR012606:Ribosomal protein S13/S15, N-terminal, IPR023029:Ribosomal protein S15P" CG13389 11-Aug-17 DroID_v2017_08 Drer\rps13 Scer\RPS13 Cele\rps-13 Xtro\rps13 Mmus\Rps13 Hsap\RPS13 embryonic stage -- adult stage "developmental rate defective,lethal,recessive,visible,Minute,dominant,size defective,lethal - all die before end of pupal stage,some die during pupal stage" "prothoracic gland,macrochaeta,scutellar bristle,adult heart" DRSC03419 IEK 0.127403158 -1.80179533 -6.300514182 -5.071674796 3.76989015 2.252644918 FBgn0267932 CR46212 - http://flybase.org/reports/FBgn0267932 non_protein_coding_gene - - - "CR46212, lincRNA.491" - CR46212 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014874 Pt5 Protein 5 http://flybase.org/reports/FBgn0014874 - gene - - - Pt5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085395 Shawl Shaw-like http://flybase.org/reports/FBgn0085395 protein_coding_gene voltage-gated cation channel activity ; GO:0022843 | inferred from sequence or structural similarity with eag voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000164970 protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 potassium ion transport ; GO:0006813 | inferred from sequence or structural similarity with eag potassium ion transmembrane transport ; GO:0071805 | inferred from biological aspect of ancestor with PANTHER:PTN000164970 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000164970 voltage-gated potassium channel complex ; GO:0008076 | inferred from sequence or structural similarity with eag "CG13111, CG4450, shawl, Shawl, CG34366, Kv3, Kv3.2" "IPR011333:SKP1/BTB/POZ domain, IPR003968:Potassium channel, voltage dependent, Kv, IPR003974:Potassium channel, voltage dependent, Kv3, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR005821:Ion transport domain, IPR028325:Voltage-gated potassium channel, IPR000210:BTB/POZ domain, IPR015572:Potassium channel, voltage dependent, Shaw, invertebrate" CG34366 11-Aug-17 DroID_v2017_08 "Drer\kcnv2a, Drer\kcng2, Drer\si:dkey-201i6.2, Drer\kcnc1a, Drer\si:dkey-192j17.1, Drer\kcnc2, Drer\kcnf1b, Drer\kcnc1b, Drer\kcnb2, Drer\kcnc3a, Drer\kcng4a, Drer\kcns3b, Drer\kcng4b, Drer\si:rp71-39b20.4, Drer\kcnf1a, Drer\kcnv2b, Drer\kcnc3b, Drer\si:dkey-43k4.5, Drer\kcnc4, Drer\si:ch73-334d15.4, Drer\kcnb1, Drer\kcns3a" - "Cele\shw-1, Cele\shw-3, Cele\egl-36" "Xtro\kcnv2, Xtro\kcnf1, Xtro\kcng4, Xtro\kcng2, Xtro\kcnc4, Xtro\kcnb2, Xtro\kcng1, Xtro\kcns3, Xtro\kcns1, Xtro\kcnb1, Xtro\kcnv1" "Mmus\Kcnc2, Mmus\Kcnc4, Mmus\Kcnc1, Mmus\Kcnv1, Mmus\Kcns2, Mmus\Kcng1, Mmus\Kcnf1, Mmus\Kcng4, Mmus\Kcng2, Mmus\Kcnc3, Mmus\Kcns3, Mmus\Kcnv2, Mmus\Kcnb1, Mmus\Kcng3, Mmus\Kcns1, Mmus\Kcnb2" "Hsap\KCNC2, Hsap\KCNS2, Hsap\KCNB2, Hsap\KCNG3, Hsap\KCNS3, Hsap\KCNB1, Hsap\KCNS1, Hsap\KCNC3, Hsap\KCNF1, Hsap\KCNG1, Hsap\KCNG4, Hsap\KCNC4, Hsap\KCNV1, Hsap\KCNC1, Hsap\KCNG2, Hsap\KCNV2" FBgn0033429 CG12929 - http://flybase.org/reports/FBgn0033429 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12929 IPR018908:Putative transmembrane family 234 CG12929 11-Aug-17 DroID_v2017_08 Drer\tmem234 - Cele\F53F10.8 Xtro\tmem234 Mmus\Tmem234 Hsap\TMEM234 viable FBgn0001804 l(1)Mc32 lethal (1) Mc32 http://flybase.org/reports/FBgn0001804 - gene - - - l(1)Mc32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0267611 CR45949 - http://flybase.org/reports/FBgn0267611 non_protein_coding_gene - - - CR45949 - CR45949 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033131 CR12842 - http://flybase.org/reports/FBgn0033131 pseudogene_attribute - - - "CR12842, CG12842" - CR12842 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0031756 CG13992 - http://flybase.org/reports/FBgn0031756 protein_coding_gene - - - CG13992 - CG13992 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085196 CG34167 - http://flybase.org/reports/FBgn0085196 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34167 - CG34167 11-Aug-17 DroID_v2017_08 - - Cele\W08E12.2 - Mmus\Lce1h Hsap\KRTAP5-6 FBgn0267166 CR45606 - http://flybase.org/reports/FBgn0267166 non_protein_coding_gene - - - CR45606 - CR45606 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261984 Ire1 Inositol-requiring enzyme-1 http://flybase.org/reports/FBgn0261984 protein_coding_gene "protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 endoribonuclease activity ; GO:0004521 | inferred from mutant phenotype protein kinase activity ; GO:0004672 | non-traceable author statement endoribonuclease activity ; GO:0004521 | inferred from direct assay" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271 response to endoplasmic reticulum stress ; GO:0034976 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement compound eye photoreceptor fate commitment ; GO:0001752 | NOT inferred from mutant phenotype regulation of RNA splicing ; GO:0043484 | inferred from direct assay mRNA endonucleolytic cleavage involved in unfolded protein response ; GO:0070055 | inferred from mutant phenotype endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from direct assay compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype rhabdomere morphogenesis ; GO:0061541 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from mutant phenotype" - "CG4583, ERN1, ire1, Ire1, ire-1, IRE1, dire-1, IRE-like, Ire-1, dIRE1, Ire" "IPR018391:Pyrrolo-quinoline quinone beta-propeller repeat, IPR033523:Serine/threonine-protein kinase/endoribonuclease IRE2, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR010513:KEN domain, IPR011009:Protein kinase-like domain, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR018997:PUB domain" CG4583 11-Aug-17 DroID_v2017_08 "Drer\LOC100334396, Drer\ern1, Drer\LOC101886687, Drer\ern2" Scer\IRE1 Cele\ire-1 Xtro\ern2 "Mmus\Ern2, Mmus\Ern1, Mmus\Rnasel" "Hsap\ERN2, Hsap\RNASEL, Hsap\ERN1" FBgn0034242 CG14480 - http://flybase.org/reports/FBgn0034242 protein_coding_gene - - - CG14480 "IPR019331:FAM192A/Fyv6, N-terminal" CG14480 11-Aug-17 DroID_v2017_08 Drer\fam192a - "Cele\C25A1.1, Cele\ZC190.9, Cele\Y75D11A.1" Xtro\fam192a Mmus\Fam192a Hsap\FAM192A viable FBgn0024221 ird6 immune response deficient 6 http://flybase.org/reports/FBgn0024221 - gene - positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype - ird6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,immune response defective,melanotic mass phenotype" melanotic mass FBgn0264704 CR43973 - http://flybase.org/reports/FBgn0264704 non_protein_coding_gene - - - CR43973 - CR43973 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003567 su(Hw) suppressor of Hairy wing http://flybase.org/reports/FBgn0003567 FBgn0015225 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V8P9 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q86B87 chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24478 DNA binding ; GO:0003677 | inferred from mutant phenotype sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VYX1 "negative regulation of chromatin silencing ; GO:0031936 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "CG8573, su(HW), Su(Hw), Su(HW), Su(hw), su(hw), Su[Hw], su(Hw), SU(HW), suHw, SUHW" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8573 11-Aug-17 DroID_v2017_08 "Drer\LOC101884305, Drer\znf1034" - "Cele\hinf-1, Cele\F47E1.3, Cele\Y111B2A.10, Cele\Y55F3AM.14" - "Mmus\Prdm14, Mmus\Zfp148, Mmus\Gzf1, Mmus\Zfp281" "Hsap\ZNF281, Hsap\PRDM14, Hsap\ZNF740, Hsap\PRDM15, Hsap\ZNF501, Hsap\ZNF148" " embryonic stage -- adult stage , oogenesis stage && adult stage | female " ovary

" embryonic stage -- adult stage , adult stage | female , adult stage | male " "female sterile,wild-type,male sterile,recessive,viable,lethal,heat sensitive,visible,partially lethal - majority die,some die during pupal stage" "cuticle,egg chamber,trichogen cell" FBgn0010119 l(1)2Db lethal (1) 2Db http://flybase.org/reports/FBgn0010119 - gene - - - "l(1)107, l(1)2Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032191 CG5734 - http://flybase.org/reports/FBgn0032191 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 phosphatidylinositol binding ; GO:0035091 | inferred from sequence or structural similarity with HGNC:14979 "retrograde transport, endosome to plasma membrane ; GO:1990126 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000965695" early endosome ; GO:0005769 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 intracellular membrane-bounded organelle ; GO:0043231 | inferred from sequence or structural similarity with HGNC:14979 "CG5734, DmSNX17" "IPR001683:Phox homologous domain, IPR028666:Sorting nexin-17" CG5734 11-Aug-17 DroID_v2017_08 Drer\snx17 - Cele\snx-17 "Xtro\snx17, Xtro\snx31" "Mmus\Snx17, Mmus\Snx31" "Hsap\SNX17, Hsap\SNX31" viable FBgn0085826 CR41620 - http://flybase.org/reports/FBgn0085826 rRNA_gene - - - CR41620 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027312 l(1)G0097 lethal (1) G0097 http://flybase.org/reports/FBgn0027312 - gene - - - l(1)G0097 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0045969 Tabor\gag Tabor element gag http://flybase.org/reports/FBgn0045969 transposable_element_gene - - - "ORF1, Pilgrim\gag, Tabor\gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033160 Dhx15 DEAH-box helicase 15 http://flybase.org/reports/FBgn0033160 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000003088 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD:S000003088 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity "positive regulation of p38MAPK cascade ; GO:1900745 | inferred from genetic interaction with p38a mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000003088 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000434138 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000003088 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG11107, cg11107, clone 1.18, anon-EST:Liang-1.18, Dhx15, DHX15" "IPR001650:Helicase, C-terminal, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011545:DEAD/DEAH box helicase domain" CG11107 11-Aug-17 DroID_v2017_08 "Drer\dhx16, Drer\dhx33, Drer\dhx15, Drer\zgc:158828, Drer\dhx32a, Drer\dhx38, Drer\dhx8, Drer\dhx32b" "Scer\PRP16, Scer\PRP2, Scer\PRP43, Scer\PRP22" "Cele\mog-1, Cele\let-355, Cele\mog-5, Cele\ddx-15, Cele\mog-4" "Xtro\dhx16, Xtro\dhx38, Xtro\dhx15, Xtro\dhx35, Xtro\dhx33, Xtro\dhx8" "Mmus\Dhx32, Mmus\Dhx35, Mmus\Dhx15, Mmus\Dhx16, Mmus\Dhx8, Mmus\Dhx38, Mmus\Dqx1, Mmus\Dhx33" "Hsap\DHX32, Hsap\DHX8, Hsap\DHX15, Hsap\DHX35, Hsap\DHX38, Hsap\DHX33, Hsap\DHX16, Hsap\DQX1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0024710 anon-63Eb anon-63Eb http://flybase.org/reports/FBgn0024710 - gene - - - anon-63Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062628 Mod(var)1038 Mod(var)1038 http://flybase.org/reports/FBgn0062628 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1038, Mod(var)1038" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0005746 l(1)TK238 lethal (1) TK238 http://flybase.org/reports/FBgn0005746 - gene - - - "l238, l(1)TK238" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0061175 btl::htl btl::htl http://flybase.org/reports/FBgn0061175 engineered_fusion_gene - - - btl::htl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265700 CR44507 - http://flybase.org/reports/FBgn0265700 non_protein_coding_gene - - - "lincRNA.966, CR44507" - CR44507 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065984 iab-4-6.s iab-4-6.s http://flybase.org/reports/FBgn0065984 gene - - - "4-6 s, iab-4-6.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259545 GG01156 - http://flybase.org/reports/FBgn0259545 gene - - - GG01156 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible mediproboscis FBgn0053920 CG33920 - http://flybase.org/reports/FBgn0053920 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33920 IPR010512:Protein of unknown function DUF1091 CG33920 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0265500 CR44369 - http://flybase.org/reports/FBgn0265500 non_protein_coding_gene - - - CR44369 - CR44369 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015353 anon-99Cb anon-99Cb http://flybase.org/reports/FBgn0015353 - gene - - - anon-99Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0038578 MED17 Mediator complex subunit 17 http://flybase.org/reports/FBgn0038578 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 inferred from physical interaction with UniProtKB:Q9V439 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with HGNC:2375 activating transcription factor binding ; GO:0033613 | inferred from physical interaction with Hsf inferred from physical interaction with Dif transcription coactivator activity ; GO:0003713 | contributes_to inferred from direct assay transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs sex comb development ; GO:0045498 | inferred from genetic interaction with Scr cellular process ; GO:0009987 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:2375 nuclear pericentric heterochromatin ; GO:0031618 | inferred from physical interaction with Su(var)205 inferred from physical interaction with MED26 nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from sequence or structural similarity with HGNC:2375 mediator complex ; GO:0016592 | inferred from direct assay "Trap80, Med17, TRAP80, dTRAP80, p70, dTRAP80/SRB4, l(3)s2956, dTrap80, CG7957, MED17" "IPR019313:Mediator complex, subunit Med17" CG7957 11-Aug-17 DroID_v2017_08 Drer\med17 Scer\SRB4 Cele\mdt-17 Xtro\med17 Mmus\Med17 Hsap\MED17 "lethal,recessive,cell lethalcell lethal,somatic clone" embryonic/larval brain DRSC16889 IEK 0.763828301 2.94083354 -3.380947175 -0.475176501 3.150046955 2.289141517 FBgn0067641 trou trou http://flybase.org/reports/FBgn0067641 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available trou - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,female sterile" "egg chamber,germline clone,egg" FBgn0283659 THG tRNA-histidine guanylyltransferase http://flybase.org/reports/FBgn0283659 protein_coding_gene "tRNA guanylyltransferase activity ; GO:0008193 | inferred from electronic annotation with InterPro:IPR007537, InterPro:IPR024956 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR007537, InterPro:IPR024956" "tRNA modification ; GO:0006400 | inferred from electronic annotation with InterPro:IPR007537, InterPro:IPR024956 neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "CG4103, THG, tRNA-guanylyltransferase, l(2)35Bc, br4, l(2)br4, l(2)br, l(2)br13, l(2)br11, C1, l(2)k08808, BG:DS00929.4" "IPR024956:tRNAHis guanylyltransferase catalytic domain, IPR025845:Thg1 C-terminal domain, IPR007537:tRNAHis guanylyltransferase Thg1" CG4103 11-Aug-17 DroID_v2017_08 Drer\thg1l Scer\THG1 - "Xtro\LOC101733043, Xtro\thg1l" Mmus\Thg1l Hsap\THG1L FBgn0027554 CG8042 - http://flybase.org/reports/FBgn0027554 "FBgn0044624, FBgn0046406" protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay "BcDNA:GH10229, anon-WO0172774.24, anon-WO0140519.245, CG8042" "IPR001012:UBX domain, IPR012336:Thioredoxin-like fold, IPR029071:Ubiquitin-related domain" CG8042 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-173p19.1, Drer\ubxn4, Drer\ubxn1" "Scer\UBX7, Scer\UBX6" "Cele\ubxn-1, Cele\ubxn-4" "Xtro\ubxn4, Xtro\ubxn1" "Mmus\Ubxn1, Mmus\Ubxn4" "Hsap\UBXN1, Hsap\UBXN4" viable FBgn0026185 rdgG retinal degeneration G http://flybase.org/reports/FBgn0026185 - gene - - - rdgG - - 11-Aug-17 DroID_v2017_08 - - - - - - visual behavior defective "photoreceptor cell,retina" FBgn0028927 CG31834 - http://flybase.org/reports/FBgn0028927 protein_coding_gene - - - "BG:DS00929.16, DS00929.16, CG31834" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058181 CG40181 - http://flybase.org/reports/FBgn0058181 protein_coding_gene - - - CG40181 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015261 Moorea Moorea http://flybase.org/reports/FBgn0015261 - region - - - Moorea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011436 l(3)j12B4 lethal (3) j12B4 http://flybase.org/reports/FBgn0011436 - gene - - - l(3)j12B4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044519 fs(1)124 female sterile (1) 124 http://flybase.org/reports/FBgn0044519 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)124 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "germarium,egg chamber" FBgn0005556 l(3)89Ee lethal (3) 89Ee http://flybase.org/reports/FBgn0005556 "FBgn0002368, FBgn0002439" gene - - - "lrb, lbr, lrB, l(3)rB, l(3)89Ee" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015582 dare defective in the avoidance of repellents http://flybase.org/reports/FBgn0015582 - protein_coding_gene NADPH-adrenodoxin reductase activity ; GO:0015039 | inferred from sequence or structural similarity with UniProtKB:P22570 NADPH-adrenodoxin reductase activity ; GO:0015039 | inferred from biological aspect of ancestor with PANTHER:PTN000234268 electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with UniProtKB:P22570 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR021163, InterPro:IPR023753 steroid biosynthetic process ; GO:0006694 | inferred from expression pattern inferred from direct assay molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype cholesterol catabolic process ; GO:0006707 | inferred from sequence or structural similarity with UniProtKB:P22570 pupariation ; GO:0035073 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P22570 "W8, AR, CG12390, dare, Dare" "IPR021163:Ferredoxin-NADP+ reductase, adrenodoxin-type, IPR023753:FAD/NAD(P)-binding domain" CG12390 11-Aug-17 DroID_v2017_08 "Drer\fdxr, Drer\cmtr2" "Scer\ARH1, Scer\GLT1" Cele\Y62E10A.6 "Xtro\cmtr2, Xtro\fdxr" "Mmus\Cmtr2, Mmus\Fdxr" Hsap\FDXR " adult stage , larval stage | third instar , adult stage && oogenesis stage | stage >=S6 " " ring gland

, nurse cell

, ovary

, prothoracic gland

" "viable,smell perception defective,recessive,courtship behavior defective,male,behavior defective,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,dominant,maternal effect" "antennal lobe,optic lobe,ellipsoid body,fan-shaped body,thoracico-abdominal ganglion,egg,germline clone,egg chamber,mouth hooks,embryonic/larval anterior spiracle" FBgn0038721 subdued subdued http://flybase.org/reports/FBgn0038721 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR032394 intracellular calcium activated chloride channel activity ; GO:0005229 | inferred from direct assay voltage-gated chloride channel activity ; GO:0005247 | inferred from direct assay temperature-gated ion channel activity ; GO:0097603 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype - "CG16718, subdued" "IPR007632:Anoctamin, IPR032394:Anoctamin, dimerisation domain" CG16718 11-Aug-17 DroID_v2017_08 "Drer\LOC562630, Drer\si:dkey-83h2.5, Drer\LOC103910000, Drer\ano1, Drer\ano6, Drer\ano9b, Drer\ano5b, Drer\LOC563500, Drer\ano5a, Drer\ano8a, Drer\ano3, Drer\LOC101886884, Drer\ano8b, Drer\ano2, Drer\ano11" Scer\IST2 "Cele\anoh-2, Cele\anoh-1" "Xtro\ano2, Xtro\ano3, Xtro\ano1, Xtro\ano9, Xtro\ano5" "Mmus\Ano2, Mmus\Ano7, Mmus\Ano1, Mmus\Ano8, Mmus\Ano4, Mmus\Ano3, Mmus\Ano5, Mmus\Ano9, Mmus\Ano6" "Hsap\ANO3, Hsap\ANO6, Hsap\ANO1, Hsap\ANO2, Hsap\ANO8, Hsap\ANO7, Hsap\ANO4, Hsap\ANO9, Hsap\ANO5" "immune response defective,viable,fertile" FBgn0051143 tRNA:Leu-CAA-2-3 transfer RNA:Leucine-CAA 2-3 http://flybase.org/reports/FBgn0051143 tRNA_gene UUG codon-amino acid adaptor activity ; GO:0033404 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033404 cytosol ; GO:0005829 | inferred by curator from GO:0033404 "AE002708.trna37-LeuCAA, tRNA:L:CAA:AE002708, CR31143, chr3R.trna43-LeuCAA, tRNA:LeuCAA, tRNA-Leu-CAA-2-3, tRNA:Leu-CAA-2-3, tRNA:CR31143, UUG" - CR31143 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030178 CG2974 - http://flybase.org/reports/FBgn0030178 protein_coding_gene NADHX epimerase activity ; GO:0052856 | inferred from biological aspect of ancestor with PANTHER:PTN000325829 NADPHX epimerase activity ; GO:0052857 | inferred from biological aspect of ancestor with PANTHER:PTN000325829 - mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000325829 CG2974 "IPR004443:YjeF N-terminal domain, IPR032976:YjeF N-terminal domain-containing protein, eukaryotes" CG2974 11-Aug-17 DroID_v2017_08 "Drer\edc3, Drer\yjefn3, Drer\apoa1bp" "Scer\EDC3, Scer\YNL200C" Cele\Y18D10A.3 "Xtro\edc3, Xtro\apoa1bp" "Mmus\Ttc24, Mmus\Edc3, Mmus\Apoa1bp" "Hsap\EDC3, Hsap\YJEFN3, Hsap\NAXE" "viable,fertile,visible" trichogen cell FBgn0040962 CG15868 - http://flybase.org/reports/FBgn0040962 protein_coding_gene - - - CG15868 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058239 CG40239 - http://flybase.org/reports/FBgn0058239 protein_coding_gene - - - CG40239 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266224 CR44919 - http://flybase.org/reports/FBgn0266224 non_protein_coding_gene - - - CR44919 - CR44919 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263704 T:SS-hh Signal sequence of hh http://flybase.org/reports/FBgn0263704 engineered_tag - - - "T:SS-hh, T:hh" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086358 Tab2 TAK1-associated binding protein 2 http://flybase.org/reports/FBgn0086358 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 "positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype positive regulation of protein import into nucleus, translocation ; GO:0033160 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype" - "CG7417, TAB2, TAB, dTAB2, 7417, ORF1, Tab2, galere, tab2, cg7417, dTab2, tab-2" "IPR003892:Ubiquitin system component Cue, IPR001876:Zinc finger, RanBP2-type, IPR032675:Leucine-rich repeat domain, L domain-like" CG7417 11-Aug-17 DroID_v2017_08 "Drer\btf3l4, Drer\tab2, Drer\btf3, Drer\tab3" "Scer\EGD1, Scer\WWM1, Scer\YML020W, Scer\BTT1" Cele\icd-1 Xtro\tab2 "Mmus\Btf3, Mmus\Tab2, Mmus\Tnfrsf1a, Mmus\Tab3, Mmus\Btf3l4" "Hsap\TAB2, Hsap\BTF3L4, Hsap\BTF3, Hsap\TAB3, Hsap\TNFRSF1A" FBgn0017417 axe axed on X http://flybase.org/reports/FBgn0017417 - gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available axe - - 11-Aug-17 DroID_v2017_08 - - - - - - chordotonal organ & axon | lateral FBgn0069160 mcl(3)Z2086 mcl(3)Z2086 http://flybase.org/reports/FBgn0069160 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z2086 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0002465 l(3)SG19 lethal (3) SG19 http://flybase.org/reports/FBgn0002465 - gene - - - l(3)SG19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" eye-antennal disc FBgn0032908 CG9270 - http://flybase.org/reports/FBgn0032908 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "Dme_CG9270, CG9270" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG9270 11-Aug-17 DroID_v2017_08 "Drer\cftr, Drer\LOC100329706, Drer\abcc6a, Drer\abcc6b.2, Drer\abcc12, Drer\abcc1, Drer\abcc9, Drer\abcc10, Drer\abcc5, Drer\abcc4, Drer\abcc3, Drer\abcc13, Drer\abcc8, Drer\abcc2" "Scer\NFT1, Scer\STE6, Scer\YKR104W, Scer\VMR1, Scer\BPT1, Scer\YCF1, Scer\YBT1, Scer\YOR1" "Cele\mrp-5, Cele\mrp-4, Cele\cft-1, Cele\mrp-2, Cele\mrp-3, Cele\mrp-8, Cele\mrp-7, Cele\mrp-6, Cele\mrp-1" "Xtro\abcc1, Xtro\abcc6, Xtro\abcc10, Xtro\abcc4, Xtro\abcc3, Xtro\cftr" "Mmus\Abcc10, Mmus\Abcc5, Mmus\Abcc1, Mmus\Abcc4, Mmus\Abcc9, Mmus\Abcc8, Mmus\Abcc12, Mmus\Cftr, Mmus\Abcc3, Mmus\Abcc2, Mmus\Abcc6" "Hsap\ABCC4, Hsap\ABCC1, Hsap\ABCC6, Hsap\ABCC3, Hsap\ABCC8, Hsap\ABCC5, Hsap\ABCC12, Hsap\ABCC10, Hsap\ABCC11, Hsap\ABCC2, Hsap\CFTR, Hsap\ABCC9" "viable,visible" chaeta FBgn0065670 l(2)SH0686 lethal (2) SH0686 http://flybase.org/reports/FBgn0065670 gene - - - "l(2)SH0686, l(2)SH2 0686" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011868 tRNA:Gly-GCC-1-9 transfer RNA:Glycine-GCC 1-9 http://flybase.org/reports/FBgn0011868 "FBgn0050228, FBgn0060218" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "CR30228, AE002787.trna10-GlyGCC, tRNA:G:GCC:AE002787-a, tRNA:gly3:55E, tRNA[Gly-GCC], chr2R.trna68-GlyGCC, tRNA-Gly-GCC-1-9, tRNA:Gly-GCC-1-9, tRNA:G3:55E, GGC" - CR30228 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035197 CG9130 - http://flybase.org/reports/FBgn0035197 protein_coding_gene - - - "CG32332, BEST:GH19464, BEST:GH19274, anon-WO0140519.53, anon-WO0140519.145, CG9130" - CG9130 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051340 CG31340 - http://flybase.org/reports/FBgn0051340 protein_coding_gene - - - CG31340 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069128 mei(3)M19 mei(3)M19 http://flybase.org/reports/FBgn0069128 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(3)M19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive" FBgn0003890 betaTub97EF beta-Tubulin at 97EF http://flybase.org/reports/FBgn0003890 FBgn0039567 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002453, InterPro:IPR008280, InterPro:IPR017975 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002453 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity" centrosome duplication ; GO:0051298 | inferred from mutant phenotype "microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002453, InterPro:IPR017975 microtubule ; GO:0005874 | inferred from sequence or structural similarity neuromuscular junction ; GO:0031594 | microtubule ; GO:0005874 |" "beta-Tub, beta-tub, CG4869, BETA 98B, Dmbeta4, betaTub98C, T, 4t, betaTub98BC, DTB1, beta97F, B4t, betaTub4, beta4t, beta-Tub97EF, betaTub97EF, Tub, beta4, Tub2C" "IPR000217:Tubulin, IPR002453:Beta tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain, IPR013838:Beta tubulin, autoregulation binding site" CG4869 11-Aug-17 DroID_v2017_08 "Drer\tubb5, Drer\tubb2b, Drer\zgc:65894, Drer\zgc:153426, Drer\zgc:55461, Drer\tubb1, Drer\tubb6, Drer\zgc:153264, Drer\tubb4b, Drer\tubb2" Scer\TUB2 "Cele\tbb-1, Cele\ben-1, Cele\tbb-4, Cele\tbb-2, Cele\mec-7" "Xtro\tubb4a, Xtro\tubb, Xtro\tubb6, Xtro\tubb3, Xtro\tube1, Xtro\tubb2b, Xtro\tubb4b" "Mmus\Tubb1, Mmus\Tube1, Mmus\Tubb4b, Mmus\Tubb2b, Mmus\Tubb2a, Mmus\Tubb4a, Mmus\Tubb6, Mmus\Tubb5, Mmus\Tubb3" "Hsap\TUBB4A, Hsap\TUBB2A, Hsap\TUBE1, Hsap\TUBB1, Hsap\TUBB2B, Hsap\TUBB6, Hsap\TUBB4B, Hsap\TUBB, Hsap\TUBB8, Hsap\TUBB3" " larval stage | second instar , embryonic stage | 0-21 hr , larval stage | third instar , pupal stage , prepupal stage , larval stage | first instar " "viable,fertile" DRSC15666 E 0.995962574 -0.674885018 3.76162945 -0.319934608 0.311230994 -0.491730244 FBgn0052758 CG32758 - http://flybase.org/reports/FBgn0052758 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from sequence or structural similarity with HGNC:20073 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000159 intracellular protein transport ; GO:0006886 | inferred from sequence or structural similarity with HGNC:20073 retrograde transport, endosome to plasma membrane ; GO:1990126 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000965695" early endosome ; GO:0005769 | inferred from sequence or structural similarity with HGNC:20073 early endosome ; GO:0005769 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 "CG3138, CG3130, CG11465, CG32758, DmSNX27" "IPR000159:Ras-associating (RA) domain, IPR001478:PDZ domain, IPR001683:Phox homologous domain, IPR029071:Ubiquitin-related domain" CG32758 11-Aug-17 DroID_v2017_08 "Drer\snx27a, Drer\snx13, Drer\snx14, Drer\snx27b" Scer\MDM1 "Cele\snx-14, Cele\snx-27, Cele\snx-13" Xtro\snx27 "Mmus\Snx25, Mmus\Snx13, Mmus\Snx14, Mmus\Snx27" "Hsap\SNX14, Hsap\SNX25, Hsap\SNX27, Hsap\SNX13" "viable,visible" trichogen cell FBgn0003907 tyl tinylike http://flybase.org/reports/FBgn0003907 - gene - - - "ty-l, l(1)10Cb, tyl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,visible,viable,poor,lethal" macrochaeta FBgn0067351 l(3)95Ea lethal (3) 95Ea http://flybase.org/reports/FBgn0067351 gene - - - l(3)95Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,somatic clone,mesothoracic tergum & macrochaeta | somatic clone,wing vein,wing margin" FBgn0028886 CG15279 - http://flybase.org/reports/FBgn0028886 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT cation:amino acid symporter activity ; GO:0005416 | inferred from sequence or structural similarity amino acid transmembrane import ; GO:0044745 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model "DS03431.1, BG:DS03431.1, anon-WO0149848.9, CG15279, DmNAT6" IPR000175:Sodium:neurotransmitter symporter CG15279 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-132b12.1, Drer\slc6a15, Drer\slc6a13, Drer\slc6a11a, Drer\slc6a5, Drer\slc6a16b, Drer\slc6a1l, Drer\slc6a19a.1, Drer\si:ch211-132b12.2, Drer\slc6a16a, Drer\slc6a6b, Drer\slc6a17, Drer\zgc:158225, Drer\slc6a19b, Drer\zgc:174946, Drer\slc6a2, Drer\slc6a13, Drer\slc6a4a, Drer\slc6a4b, Drer\slc6a18, Drer\slc6a1a, Drer\slc6a6a, Drer\slc6a1b, Drer\si:ch211-117c9.5, Drer\si:ch211-132b12.3, Drer\slc6a14, Drer\si:ch211-132b12.6, Drer\slc6a13l, Drer\slc6a9, Drer\slc6a8" - "Cele\snf-12, Cele\snf-5, Cele\snf-7, Cele\snf-9, Cele\snf-2, Cele\snf-11, Cele\dat-1, Cele\mod-5, Cele\snf-6, Cele\snf-3" "Xtro\slc6a7, Xtro\slc6a9, Xtro\slc6a2, Xtro\slc6a3, Xtro\slc6a14.2, Xtro\slc6a8, Xtro\slc6a19, Xtro\slc6a17, Xtro\slc6a1, Xtro\slc6a13, Xtro\slc6a15, Xtro\slc6a5, Xtro\slc6a12, Xtro\LOC100127682, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a16" "Mmus\Slc6a2, Mmus\Slc6a5, Mmus\Slc6a1, Mmus\Slc6a7, Mmus\Slc6a3, Mmus\Slc6a13, Mmus\Slc6a19, Mmus\Slc6a6, Mmus\Slc6a17, Mmus\Slc6a15, Mmus\Slc6a12, Mmus\Slc6a9, Mmus\Slc6a8, Mmus\Slc6a18, Mmus\Slc6a20b, Mmus\Slc6a11, Mmus\Slc6a14, Mmus\Slc6a20a, Mmus\Slc6a4" "Hsap\SLC6A5, Hsap\SLC6A9, Hsap\SLC6A17, Hsap\SLC6A20, Hsap\SLC6A19, Hsap\SLC6A8, Hsap\SLC6A2, Hsap\SLC6A13, Hsap\SLC6A18, Hsap\SLC6A12, Hsap\SLC6A15, Hsap\SLC6A14, Hsap\SLC6A3, Hsap\SLC6A11, Hsap\SLC6A6, Hsap\SLC6A1, Hsap\SLC6A4" viable FBgn0003705 ti tarsi irregular http://flybase.org/reports/FBgn0003705 - gene - - - ti - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority live "eye,tarsal segment 3,tarsal segment 4" FBgn0035152 CG3386 - http://flybase.org/reports/FBgn0035152 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3386 IPR006578:MADF domain CG3386 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0267031 CR45475 - http://flybase.org/reports/FBgn0267031 non_protein_coding_gene - - - CR45475 - CR45475 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060356 l(3)S140901 lethal (3) S140901 http://flybase.org/reports/FBgn0060356 gene - - - "1409/01, l(3)S140901" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0035852 CG7387 - http://flybase.org/reports/FBgn0035852 protein_coding_gene "unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001305, InterPro:IPR008971 heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001305" protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001531327 "anon-WO0140519.72, CG7387" "IPR001305:Heat shock protein DnaJ, cysteine-rich domain, IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site" CG7387 11-Aug-17 DroID_v2017_08 "Drer\dnaja3b, Drer\dnajc16l, Drer\dnajc16, Drer\dnaja3a, Drer\dnaja1, Drer\dnajc24" "Scer\SCJ1, Scer\YDJ1, Scer\MDJ1" "Cele\dnj-14, Cele\dnj-10, Cele\dnj-8, Cele\dnj-3" "Xtro\dnajc24, Xtro\dnajc16" "Mmus\Dnaja1, Mmus\Dnajc24, Mmus\Dnaja3, Mmus\Dnaja4, Mmus\Dnajc16" "Hsap\DNAJA1, Hsap\DNAJA4, Hsap\DNAJA3, Hsap\DNAJC16, Hsap\DNAJC24" "partially lethal - majority die,some die during pupal stage" FBgn0035541 CG15019 - http://flybase.org/reports/FBgn0035541 protein_coding_gene - - - CG15019 IPR018784:Learning associated protein 18-like CG15019 11-Aug-17 DroID_v2017_08 Drer\llph - Cele\C49H3.3 Xtro\llph Mmus\Llph Hsap\LLPH viable FBgn0030008 CG2129 - http://flybase.org/reports/FBgn0030008 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - heterochromatin ; GO:0000792 | inferred from direct assay CG2129 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG2129 11-Aug-17 DroID_v2017_08 "Drer\hic1l, Drer\gb:ai877918, Drer\si:dkey-7l6.3, Drer\si:ch73-138e16.2, Drer\LOC101882465, Drer\LOC101886047, Drer\zbtb43" Scer\AZF1 "Cele\pag-3, Cele\hinf-1, Cele\Y55F3AM.14, Cele\blmp-1" - "Mmus\Zfp276, Mmus\Zscan10, Mmus\Zfp775, Mmus\Zbtb43, Mmus\Zfp653" "Hsap\ZNF775, Hsap\ZNF276, Hsap\ZBTB43, Hsap\ZNF653, Hsap\ZSCAN10, Hsap\ZNF677, Hsap\ZNF614" FBgn0058092 CG40092 - http://flybase.org/reports/FBgn0058092 protein_coding_gene - - - CG40092 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015876 anon-48Ae anon-48Ae http://flybase.org/reports/FBgn0015876 - gene - - - "VII, anon-48Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262435 mir-1009 mir-1009 stem loop http://flybase.org/reports/FBgn0262435 miRNA_gene - - - "dme-mir-1009, miR-1009, mir-1009, CR42994" - CR42994 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0083269 E(smoDN)390 Enhancer of smoDN 390 http://flybase.org/reports/FBgn0083269 gene - - - E(smoDN)390 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016041 Tom40 Translocase of outer membrane 40 http://flybase.org/reports/FBgn0016041 "FBgn0027267, FBgn0029960" protein_coding_gene protein channel activity ; GO:0015266 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O96008 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O96008 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q75Q40 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from sequence or structural similarity with UniProtKB:O96008 "CG12157, dtom40, mit, ms15, l(1)G0216, ms(1)15, Tom40, tom40" IPR027246:Eukaryotic porin/Tom40 CG12157 11-Aug-17 DroID_v2017_08 "Drer\tomm40l, Drer\si:dkey-71l1.1, Drer\tomm40" Scer\TOM40 Cele\tomm-40 "Xtro\tomm40, Xtro\tomm40l" "Mmus\Tomm40, Mmus\Tomm40l" "Hsap\TOMM40L, Hsap\TOMM40" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263334 CR43415 - http://flybase.org/reports/FBgn0263334 non_protein_coding_gene - - - "CR43415, lincRNA.319" - CR43415 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027304 l(1)G0121 lethal (1) G0121 http://flybase.org/reports/FBgn0027304 - gene - - - l(1)G0121 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0041211 H23-14 H23-14 http://flybase.org/reports/FBgn0041211 gene - - - H23-14 - - 11-Aug-17 DroID_v2017_08 - - - - - - auxotroph FBgn0033591 CG13216 - http://flybase.org/reports/FBgn0033591 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13216 - CG13216 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000830 fs(1)M11 female sterile (1) M11 http://flybase.org/reports/FBgn0000830 - gene - - - fs(1)M11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0040127 l(2)23CDa lethal (2) 23CDa http://flybase.org/reports/FBgn0040127 gene - - - l(2)23CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010934 l(3)09291 lethal (3) 09291 http://flybase.org/reports/FBgn0010934 - gene - - - "P1736, l(3)09291" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0038640 CG7706 - http://flybase.org/reports/FBgn0038640 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN002359305 - - CG7706 "IPR000253:Forkhead-associated (FHA) domain, IPR008984:SMAD/FHA domain" CG7706 11-Aug-17 DroID_v2017_08 Drer\slc4a1ap - Cele\ZK632.2 Xtro\slc4a1ap Mmus\Slc4a1ap Hsap\SLC4A1AP viable FBgn0053818 His3:CG33818 His3:CG33818 http://flybase.org/reports/FBgn0053818 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33818, His3:CG33818" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33818 11-Aug-17 DroID_v2017_08 "Drer\h3f3c, Drer\cenpa, Drer\h3f3d, Drer\hist2h3ca1, Drer\si:ch73-36p18.2, Drer\h3f3a, Drer\LOC108190746, Drer\si:ch1073-429i10.3, Drer\si:dkey-23a13.8, Drer\zgc:173552, Drer\hist2h3c, Drer\zgc:113984, Drer\LOC108190747, Drer\zgc:113983, Drer\h3f3b.1" "Scer\CSE4, Scer\HHT2, Scer\HHT1" "Cele\his-63, Cele\his-74, Cele\his-71, Cele\his-69, Cele\his-13, Cele\his-25, Cele\his-42, Cele\his-32, Cele\his-72, Cele\his-49, Cele\his-27, Cele\his-59, Cele\his-6, Cele\his-2, Cele\his-9, Cele\his-17, Cele\his-55, Cele\his-45" "Xtro\cenpa, Xtro\h3f3b, Xtro\hist2h3d" "Mmus\H3f3b, Mmus\Hist1h3d, Mmus\Hist1h3i, Mmus\Cenpa, Mmus\Hist1h3h, Mmus\Hist2h3b, Mmus\Hist1h3c, Mmus\Hist1h3b, Mmus\Hist1h3a, Mmus\Hist1h3e, Mmus\Hist2h3c1, Mmus\H3f3a, Mmus\Hist1h3f, Mmus\Hist2h3c2, Mmus\Hist1h3g" "Hsap\HIST2H3D, Hsap\HIST1H3C, Hsap\HIST3H3, Hsap\HIST1H3J, Hsap\CENPA, Hsap\H3F3B, Hsap\H3F3C, Hsap\H3F3A, Hsap\HIST2H3A, Hsap\HIST1H3F, Hsap\HIST1H3E, Hsap\HIST1H3D, Hsap\HIST1H3A, Hsap\HIST2H3C, Hsap\HIST1H3G, Hsap\HIST1H3I, Hsap\HIST1H3B, Hsap\HIST1H3H" FBgn0002523 lacquered lacquered http://flybase.org/reports/FBgn0002523 - gene - - - "lac, lacquered" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,reduced,viable,eye color defective,body color defective,visible,recessive" "macrochaeta,eye,wing" FBgn0264724 CR43992 - http://flybase.org/reports/FBgn0264724 non_protein_coding_gene - - - "CR43992, lincRNA.567" - CR43992 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060303 l(3)SzB87Da lethal (3) SzB87Da http://flybase.org/reports/FBgn0060303 gene - - - "1132/08, 0098/05, 0074/03, l(3)SzB87Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011921 tRNA:iMet-CAT-2-1 transfer RNA:initiator Methionine-CAT 2-1 http://flybase.org/reports/FBgn0011921 "FBgn0050003, FBgn0050262, FBgn0060138" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "AE002787.trna31-MetCAT, tRNA:M:CAT:AE002787-c, tRNA:met3:46A, CR30262, CR30003, tRNA:met:46A, tRNA[Met-ATG], chr2R.trna13-MetCAT, tRNA-iMet-CAT-2-1, tRNA:iMet-CAT-2-1, tRNA:M3:46A" - CR30003 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020633 Mcm7 Minichromosome maintenance 7 http://flybase.org/reports/FBgn0020633 FBgn0025980 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008050, InterPro:IPR018525 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008050, InterPro:IPR018525 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR008050 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008050 MCM complex ; GO:0042555 | inferred from electronic annotation with InterPro:IPR008050 microtubule associated complex ; GO:0005875 | inferred from direct assay "MCM7, mcm7, CG4978, DmMCM7, PCR1, clone 1.66, anon-EST:Liang-1.66, Mcp-PCR1, Mcm7, McM7, DmeMCM7, dMcm7" "IPR018525:Mini-chromosome maintenance, conserved site, IPR001208:MCM domain, IPR003593:AAA+ ATPase domain, IPR008050:DNA replication licensing factor Mcm7, IPR012340:Nucleic acid-binding, OB-fold, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033762:MCM OB domain, IPR027925:MCM N-terminal domain, IPR031327:Mini-chromosome maintenance protein" CG4978 11-Aug-17 DroID_v2017_08 Drer\mcm7 "Scer\MCM7, Scer\MCM4" Cele\mcm-7 Xtro\mcm7 Mmus\Mcm7 Hsap\MCM7 " embryonic stage | 0-4 hr , embryonic stage | stage 11-12 , egg stage | unfertilized egg , adult stage | female " " embryonic central nervous system

, unfertilized egg

" "viable,fertile,radiation sensitive" FBgn0028266 l(1)G0444 lethal (1) G0444 http://flybase.org/reports/FBgn0028266 gene - - - l(1)G0444 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0060668 l(3)S080301 lethal (3) S080301 http://flybase.org/reports/FBgn0060668 gene - - - "0803/01, l(3)S080301" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031739 CG14005 - http://flybase.org/reports/FBgn0031739 protein_coding_gene - - - CG14005 IPR026095:Myb/SANT-like DNA-binding domain-containing protein CG14005 11-Aug-17 DroID_v2017_08 Drer\msantd1 - - - Mmus\Msantd1 Hsap\MSANTD1 "viable,fertile" embryonic/larval salivary gland FBgn0058275 CG40275 - http://flybase.org/reports/FBgn0058275 protein_coding_gene - - - CG40275 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002072 l(2)49Fa lethal (2) 49Fa http://flybase.org/reports/FBgn0002072 - gene - - - "vr3, vr-3, l(2)vr3, l(2)6, l(2)49Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die,heat sensitive,non-suppressor of variegation,dominant" FBgn0085336 CG34307 - http://flybase.org/reports/FBgn0085336 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34307 - CG34307 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015937 emu emu http://flybase.org/reports/FBgn0015937 - gene DNA binding ; GO:0003677 | inferred from sequence or structural similarity biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bk36, emu" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267511 28SrRNA-Psi:CR45851 28S ribosomal RNA pseudogene:CR45851 http://flybase.org/reports/FBgn0267511 pseudogene_attribute - - - "28SrRNA-Psi:CR45851, CR45851" - CR45851 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003070 Pfd Pufdi http://flybase.org/reports/FBgn0003070 - gene - - - Pfd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "wing,cold sensitive" FBgn0267603 CR45941 - http://flybase.org/reports/FBgn0267603 non_protein_coding_gene - - - CR45941 - CR45941 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037856 Leash Leash http://flybase.org/reports/FBgn0037856 protein_coding_gene - regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype cytoplasmic vesicle ; GO:0031410 | inferred from direct assay "CG32471, CG4674, leash, Leash" "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG4674 11-Aug-17 DroID_v2017_08 "Drer\arrdc3b, Drer\arrdc3a, Drer\arrdc1a, Drer\txnipb, Drer\LOC799768, Drer\txnipa, Drer\arrdc2, Drer\si:ch211-130m23.2, Drer\zgc:110626, Drer\zgc:110353, Drer\arrdc1b" "Scer\ART5, Scer\ALY1, Scer\CSR2, Scer\RIM8, Scer\ALY2, Scer\ROG3, Scer\LDB19, Scer\ECM21, Scer\ROD1" "Cele\arrd-22, Cele\arrd-5, Cele\arrd-19, Cele\arrd-3, Cele\rnh-1.2, Cele\arrd-4, Cele\arrd-6, Cele\arrd-16, Cele\arrd-13, Cele\arrd-24, Cele\arrd-18, Cele\arrd-7, Cele\arrd-23, Cele\arrd-25, Cele\arrd-8, Cele\arrd-27, Cele\arrd-15, Cele\arrd-1, Cele\arrd-12, Cele\arrd-14, Cele\arrd-9, Cele\arrd-11, Cele\arrd-2" "Xtro\arrdc3, Xtro\txnip, Xtro\arrdc2, Xtro\arrdc4" "Mmus\Arrdc2, Mmus\Arrdc3, Mmus\Arrdc4, Mmus\Txnip, Mmus\Arrdc1, Mmus\Arrdc5" "Hsap\ARRDC3, Hsap\ARRDC1, Hsap\ARRDC4, Hsap\ARRDC5, Hsap\TXNIP, Hsap\ARRDC2" "viable,fertile,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,size defective" "neurite | pharate adult stage,wing" FBgn0027274 l(1)G0202 lethal (1) G0202 http://flybase.org/reports/FBgn0027274 - gene - - - l(1)G0202 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,female sterile" egg FBgn0038162 CG14368 - http://flybase.org/reports/FBgn0038162 protein_coding_gene - - - CG14368 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC14830 K -0.838792933 1.29471163 0.301042628 0.123035314 1.724436304 0.751494515 FBgn0030782 CG18358 - http://flybase.org/reports/FBgn0030782 protein_coding_gene - - - "CG9644, BcDNA:RE13557, CG18358" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031150 bves bves http://flybase.org/reports/FBgn0031150 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006916 "CG1754, CG15448, CG32513, BcDNA:SD21670, bves" "IPR006916:Popeye protein, IPR018490:Cyclic nucleotide-binding-like, IPR014710:RmlC-like jelly roll fold" CG32513 11-Aug-17 DroID_v2017_08 "Drer\popdc3, Drer\bves, Drer\popdc2" - - "Xtro\popdc2, Xtro\popdc3, Xtro\bves" "Mmus\Bves, Mmus\Popdc3, Mmus\Popdc2" "Hsap\POPDC3, Hsap\POPDC2, Hsap\BVES" "lethal - all die before end of embryonic stage,maternal effect,heat sensitive,some die during embryonic stage,hyperactive,conditional,chemical resistant,viable,fertile" FBgn0086081 snoRNA:Me28S-A30 - http://flybase.org/reports/FBgn0086081 snoRNA_gene - - - "snoRNA:Me28S-A30, Me28S-Am30, CR34710" - CR34710 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038827 Fancd2 Fancd2 http://flybase.org/reports/FBgn0038827 protein_coding_gene DNA polymerase binding ; GO:0070182 | inferred from biological aspect of ancestor with PANTHER:PTN000788426 intra-S DNA damage checkpoint ; GO:0031573 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype interstrand cross-link repair ; GO:0036297 | inferred from mutant phenotype interstrand cross-link repair ; GO:0036297 | inferred from mutant phenotype inferred from genetic interaction with spel1 nucleus ; GO:0005634 | inferred by curator from GO:0036297 condensed chromosome ; GO:0000793 | inferred from biological aspect of ancestor with PANTHER:PTN000788426 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000788426 "dmFANCD2, CG17269, CG31194, FANCD2, CG31192, Fancd2, FAD" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR029448:Fanconi anaemia protein FANCD2" CG17269 11-Aug-17 DroID_v2017_08 "Drer\fancd2, Drer\nup188, Drer\tex264a" - "Cele\C52E2.4, Cele\fcd-2" "Xtro\nup188, Xtro\fancd2" "Mmus\Fancd2, Mmus\Nup188" "Hsap\FANCD2, Hsap\NUP188" "visible,chemical conditional,tumorigenic,chemical sensitive,viable,mitotic cell cycle defective,conditional,lethal - all die before end of pupal stage,some die during pupal stage" "eye,chemical conditional,trichogen cell,mesothoracic tergum" FBgn0020868 anon-R258 anon-R258 http://flybase.org/reports/FBgn0020868 - gene - - - "2-R258, anon-R258" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0000896 fs(1)M103 female sterile (1) M103 http://flybase.org/reports/FBgn0000896 - gene - - - fs(1)M103 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" FBgn0083088 hella hella http://flybase.org/reports/FBgn0083088 gene - - - hella - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001802 l(1)Mc24 lethal (1) Mc24 http://flybase.org/reports/FBgn0001802 - gene - - - l(1)Mc24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0065407 l(2)SH1579 lethal (2) SH1579 http://flybase.org/reports/FBgn0065407 gene - - - "l(2)SH1579, l(2)SH2 1579" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034282 Mapmodulin Mapmodulin http://flybase.org/reports/FBgn0034282 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity nucleocytoplasmic transport ; GO:0006913 | inferred from sequence or structural similarity with UniProtKB:P39687 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P39687 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P39687 nucleoplasm ; GO:0005654 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from sequence or structural similarity with UniProtKB:P39687 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:P39687 "CT42180, CT18148, CG5784, anon-EST:fe3A2, Mapmodulin" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG5784 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-267j14.7, Drer\anp32e, Drer\anp32a, Drer\nap1l4a, Drer\anp32b" - "Cele\F33H2.3, Cele\T19H12.2" "Xtro\anp32a, Xtro\anp32c, Xtro\anp32b, Xtro\anp32e" "Mmus\Shoc2, Mmus\Anp32b, Mmus\Anp32a, Mmus\Lrriq3, Mmus\Anp32e" "Hsap\LRRIQ3, Hsap\ANP32A, Hsap\ANP32C, Hsap\ANP32D, Hsap\ANP32E, Hsap\ANP32B, Hsap\SHOC2" viable embryonic/larval hemocyte | third instar larval stage FBgn0034201 CG17290 - http://flybase.org/reports/FBgn0034201 protein_coding_gene - - - "BcDNA:RE15976, CG17290" IPR004011:GYR motif CG17290 11-Aug-17 DroID_v2017_08 - - - - - - "viable,planar polarity defective,partially lethal - majority die,some die during pupal stage" FBgn0014156 e(y)7 enhancer of yellow 7 http://flybase.org/reports/FBgn0014156 - gene - - - e(y)7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050406 tRNA:Gly-TCC-2-2 transfer RNA:Glycine-TCC 2-2 http://flybase.org/reports/FBgn0050406 tRNA_gene GGA codon-amino acid adaptor activity ; GO:0033463 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033463 cytosol ; GO:0005829 | inferred by curator from GO:0033463 "AE002575.trna10-GlyTCC, tRNA[Gly][[GGA]], tRNA:gly:58AB, tRNA:G:58AB, tRNA:G:TCC:AE002575-a, CR30204, CR30406, chr2R.trna54-GlyTCC, tRNA-Gly-TCC-2-2, tRNA:Gly-TCC-2-2, tRNA:CR30406, GGA" - CR30406 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038834 RpS30 Ribosomal protein S30 http://flybase.org/reports/FBgn0038834 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR006846 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR006846 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR006846 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CG15697, S30, anon-EST:Posey127, RpS30, Rps30, Q9VDH8_DROME, RpS30a" "IPR006846:Ribosomal protein S30, IPR029071:Ubiquitin-related domain" CG15697 11-Aug-17 DroID_v2017_08 "Drer\faua, Drer\faub" "Scer\RPS30A, Scer\RPS30B" Cele\rps-30 Xtro\fau Mmus\Fau Hsap\FAU "lethal - all die before end of pupal stage,some die during pupal stage" DRSC26355 EK -0.6136451 -0.848712464 0.400387375 -3.487692823 2.538829726 4.223686726 FBgn0038978 tHMG1 testis-enriched HMG-box-containing protein 1 http://flybase.org/reports/FBgn0038978 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from direct assay - cytoplasm ; GO:0005737 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG7045, tHMG1, tHMG-1, thmg-1" IPR009071:High mobility group box domain CG7045 11-Aug-17 DroID_v2017_08 "Drer\tfam, Drer\tox4a, Drer\tox4b, Drer\hmgb1a, Drer\hmgb3a, Drer\hmgb2a, Drer\tox3, Drer\ubtf, Drer\hmgb2b, Drer\hmg20b, Drer\hmgb3b, Drer\hmgb1b, Drer\ubtfl, Drer\tox, Drer\hmg20a" "Scer\POB3, Scer\NHP6A, Scer\ABF2, Scer\NHP6B, Scer\HMO1, Scer\IXR1, Scer\NHP10" "Cele\hmg-1.2, Cele\hmg-4, Cele\hmg-1.1" "Xtro\tox2, Xtro\tox, Xtro\tox4, Xtro\hmgb3, Xtro\tfam, Xtro\ubtf, Xtro\hmg20b, Xtro\tox3, Xtro\hmg20a, Xtro\hmgb2, Xtro\hmgb1" "Mmus\Tox2, Mmus\Ubtf, Mmus\Hmgb1, Mmus\Tox, Mmus\Hmgb3, Mmus\Hmg20b, Mmus\Hmg20a, Mmus\Tox3, Mmus\Tfam, Mmus\Ubtfl1, Mmus\Hmgb4, Mmus\Tox4, Mmus\Hmgb2" "Hsap\TOX2, Hsap\HMG20B, Hsap\TFAM, Hsap\HMGB4, Hsap\HMGB3, Hsap\HMG20A, Hsap\UBTF, Hsap\HMGB2, Hsap\TOX3, Hsap\TOX4, Hsap\HMGB1, Hsap\TOX" viable FBgn0266047 CG44812 - http://flybase.org/reports/FBgn0266047 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44812 - CG44812 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011223 hall halley http://flybase.org/reports/FBgn0011223 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "hal, hall" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile spermatid FBgn0031526 CG8838 - http://flybase.org/reports/FBgn0031526 protein_coding_gene - - - "anon-WO0140519.135, CG8838" - CG8838 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030733 UQCR-14 Ubiquinol-cytochrome c reductase 14 kDa subunit http://flybase.org/reports/FBgn0030733 protein_coding_gene ubiquinol-cytochrome-c reductase activity ; GO:0008121 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000246311 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:P14927 "mitochondrial respiratory chain complex III assembly ; GO:0034551 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:P14927 cellular respiration ; GO:0045333 | inferred from mutant phenotype" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:P14927 mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 "anon-EST:Posey167, BcDNA:RH44664, CG3560, Ucrh 14KDa, Ucrh, UCR6, UQCR-14" IPR003197:Cytochrome b-c1 complex subunit 7 CG3560 11-Aug-17 DroID_v2017_08 Drer\uqcrb Scer\QCR7 Cele\T02H6.11 Xtro\LOC101732809 Mmus\Uqcrb Hsap\UQCRB FBgn0001384 l(1)2Bp lethal (1) 2Bp http://flybase.org/reports/FBgn0001384 - gene - - - l(1)2Bp - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044354 Quasimodo\env Quasimodo element env http://flybase.org/reports/FBgn0044354 transposable_element_gene - - - "cruiser\env, Quasimodo\env" "IPR012014:Retroelement-encoded protein, env-related, IPR022048:Envelope fusion protein-like" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002517 l(3)Sp17 lethal (3) Sp17 http://flybase.org/reports/FBgn0002517 - gene - - - l(3)Sp17 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0041845 E(Sev-CycE)A14 E(Sev-CycE)A14 http://flybase.org/reports/FBgn0041845 gene - - - E(Sev-CycE)A14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052565 CR32565 - http://flybase.org/reports/FBgn0052565 non_protein_coding_gene - - - CR32565 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022977 rrpD reduced receptor potential D http://flybase.org/reports/FBgn0022977 - gene - - - rrpD - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060414 l(3)S129717 lethal (3) S129717 http://flybase.org/reports/FBgn0060414 gene - - - "1297/17, l(3)S129717" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039843 CG15567 - http://flybase.org/reports/FBgn0039843 protein_coding_gene - - - CG15567 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013465 grdf grooming defective http://flybase.org/reports/FBgn0013465 - gene molecular_function ; GO:0003674 | no biological data available grooming behavior ; GO:0007625 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available grdf - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive" FBgn0011891 tRNA:Lys-CTT-1-1 transfer RNA:Lysine-CTT 1-1 http://flybase.org/reports/FBgn0011891 "FBgn0003795, FBgn0011886, FBgn0052837, FBgn0060185" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "CR32837, tRNAlys, 35SLys, tRNA[Lys][[2]], AE002769.trna9-LysCTT, tRNA:K2, tRNA:K:CTT:AE002769-d, tRNA:lys2:42Ae, chr2R.trna100-LysCTT, tRNA-Lys-CTT-1-1, tRNA:Lys-CTT-1-1, tRNA:K2:42Ae, AAG" - CR32837 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266822 CR45284 - http://flybase.org/reports/FBgn0266822 non_protein_coding_gene - - - CR45284 - CR45284 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016819 l(1)L6 lethal (1) L6 http://flybase.org/reports/FBgn0016819 - gene - - - "l(1)L6, L6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029817 CG15764 - http://flybase.org/reports/FBgn0029817 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT16792, CG15764" - CG15764 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010796 l(3)03346 lethal (3) 03346 http://flybase.org/reports/FBgn0010796 - gene - - - "l(3)03347, l(3)03346" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267419 CR45772 - http://flybase.org/reports/FBgn0267419 pseudogene_attribute - - - "CR45772, Mst77Y" - CR45772 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001753 l(1)jl lethal (1) jawless http://flybase.org/reports/FBgn0001753 - gene - - - l(1)jl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" cephalopharyngeal skeleton FBgn0001114 Glt Glutactin http://flybase.org/reports/FBgn0001114 - protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 neurexin family protein binding ; GO:0042043 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype defense response to other organism ; GO:0098542 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype basement membrane ; GO:0005604 | inferred from direct assay synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 "CT26441, CG9280, Glt" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR029058:Alpha/Beta hydrolase fold" CG9280 11-Aug-17 DroID_v2017_08 "Drer\nlgn4a, Drer\nlgn3b, Drer\nlgn2a, Drer\ces2, Drer\cell, Drer\nlgn1, Drer\nlgn2b, Drer\cel.1, Drer\ces3, Drer\nlgn3a, Drer\nlgn4b, Drer\si:ch211-93f2.1" - "Cele\C23H4.2, Cele\K11G9.2, Cele\T07H6.1, Cele\C01B10.4, Cele\nlg-1, Cele\E01G6.3, Cele\C23H4.3, Cele\ZK994.1, Cele\B0238.7, Cele\T22D1.11, Cele\ZC376.1, Cele\F55F3.2, Cele\Y71H2AM.13, Cele\C42D4.2, Cele\ZC376.2, Cele\K07C11.4, Cele\C23H4.7, Cele\T02B5.1, Cele\K11G9.1, Cele\ges-1, Cele\F15A8.6, Cele\C52A10.2, Cele\Y75B8A.3, Cele\F07C4.12, Cele\R173.3, Cele\glit-1, Cele\ZC376.3, Cele\F13H6.3, Cele\K11G9.3, Cele\T02B5.3, Cele\W02B12.4, Cele\F56C11.6" "Xtro\LOC100494782, Xtro\ces2, Xtro\nlgn2, Xtro\cel, Xtro\ces3, Xtro\nlgn3, Xtro\nlgn4x" "Mmus\Ces2a, Mmus\Ces1e, Mmus\Ces1f, Mmus\Ces2h, Mmus\Ces1c, Mmus\Ces3a, Mmus\Ces4a, Mmus\Ces1h, Mmus\Ces5a, Mmus\Ces2g, Mmus\Ces2c, Mmus\Ces2f, Mmus\Ces2e, Mmus\Ces1d, Mmus\Ces2b, Mmus\Ces3b, Mmus\Nlgn1, Mmus\Ces1g, Mmus\Cel, Mmus\Nlgn3, Mmus\Ces1b, Mmus\Nlgn2" "Hsap\NLGN3, Hsap\CES5A, Hsap\NLGN4Y, Hsap\CES2, Hsap\CES1, Hsap\NLGN4X, Hsap\CES3, Hsap\NLGN1, Hsap\NLGN2, Hsap\CEL, Hsap\CES4A" embryonic stage " dorsal neurohemal organ

, embryonic central nervous system

, apodeme

" "immune response defective,viable,short lived,conditional" FBgn0266438 PIG-Z Phosphatidylinositol glycan anchor biosynthesis class Z http://flybase.org/reports/FBgn0266438 protein_coding_gene "alpha-1,2-mannosyltransferase activity ; GO:0000026 | inferred from sequence or structural similarity with UniProtKB:Q86VD9 mannosyltransferase activity ; GO:0000030 | inferred from sequence or structural similarity with HGNC:30596 mannosyltransferase activity ; GO:0000030 | inferred from biological aspect of ancestor with PANTHER:PTN000509188" GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with HGNC:30596 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with UniProtKB:Q86VD9 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN001101712 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000509188 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:30596 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q86VD9 "CG3419, PIG-Z, CG45068" IPR005599:GPI mannosyltransferase CG45068 11-Aug-17 DroID_v2017_08 - Scer\SMP3 Cele\eif-1 - Mmus\Pigz Hsap\PIGZ FBgn0040923 CG11368 - http://flybase.org/reports/FBgn0040923 protein_coding_gene - - - "BcDNA:RH67809, CG11368" - CG11368 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0051793 CG31793 - http://flybase.org/reports/FBgn0051793 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "CG17338, CG10441, CG31793" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG31793 11-Aug-17 DroID_v2017_08 "Drer\abcc2, Drer\cftr, Drer\abcc4, Drer\abcc8, Drer\abcc9, Drer\abcc1, Drer\abcc3, Drer\abcc6a, Drer\abcc5, Drer\abcc6b.2, Drer\abcc10, Drer\abcc12, Drer\LOC100329706, Drer\abcc13" "Scer\BPT1, Scer\NFT1, Scer\STE6, Scer\YCF1, Scer\YBT1, Scer\YKR104W, Scer\VMR1, Scer\YOR1" "Cele\mrp-1, Cele\mrp-8, Cele\mrp-7, Cele\mrp-4, Cele\mrp-2, Cele\mrp-3, Cele\mrp-5, Cele\mrp-6" "Xtro\abcc1, Xtro\abcc4, Xtro\abcc10, Xtro\abcc3, Xtro\abcc6, Xtro\cftr" "Mmus\Abcc3, Mmus\Abcc9, Mmus\Abcc6, Mmus\Abcc2, Mmus\Abcc12, Mmus\Abcc1, Mmus\Cftr, Mmus\Abcc10, Mmus\Abcc5, Mmus\Abcc4, Mmus\Abcc8" "Hsap\CFTR, Hsap\ABCC3, Hsap\ABCC6, Hsap\ABCC12, Hsap\ABCC8, Hsap\ABCC2, Hsap\ABCC10, Hsap\ABCC9, Hsap\ABCC4, Hsap\ABCC1, Hsap\ABCC5, Hsap\ABCC11" "viable,visible" trichogen cell FBgn0086359 Invadolysin Invadolysin http://flybase.org/reports/FBgn0086359 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001577 peptidase activity ; GO:0008233 | inferred from direct assay cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR001577 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001577 regulation of choline O-acetyltransferase activity ; GO:1902769 | inferred from direct assay mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype electron transport chain ; GO:0022900 | inferred from direct assay mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype mitotic centrosome separation ; GO:0007100 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001577 cell leading edge ; GO:0031252 | inferred from sequence or structural similarity with UniProtKB:Q96KR4 cytoplasm ; GO:0005737 | inferred from direct assay "Invadolysin, invadolysin, DmIX-14, CG3953, IX-14, l(3)IX-14, l(3)SG34, inv" "IPR001577:Peptidase M8, leishmanolysin" CG3953 11-Aug-17 DroID_v2017_08 Drer\lmln - "Cele\Y43F4A.1, Cele\T13B5.9" - Mmus\Lmln Hsap\LMLN FBgn0085464 CG34435 - http://flybase.org/reports/FBgn0085464 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" multicellular organism reproduction ; GO:0032504 | inferred from expression pattern myosin complex ; GO:0016459 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay "CG34435, CG15780" IPR011992:EF-hand domain pair CG34435 11-Aug-17 DroID_v2017_08 "Drer\cmlc1, Drer\myl6, Drer\zgc:163073, Drer\mylz3, Drer\myl1, Drer\zgc:153867, Drer\myl4, Drer\myl13" Scer\MLC1 "Cele\mlc-7, Cele\mlc-6, Cele\cal-7, Cele\mlc-5" "Xtro\myl1, Xtro\myl4, Xtro\myl6, Xtro\myl3" "Mmus\Myl6b, Mmus\Myl4, Mmus\Myl3, Mmus\Myl6, Mmus\Myl1" "Hsap\MYL1, Hsap\MYL6B, Hsap\MYL3, Hsap\MYL6, Hsap\MYL4" FBgn0053986 CG33986 - http://flybase.org/reports/FBgn0053986 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG17014, CG7973, CG33986, FBgn0036507" IPR002557:Chitin binding domain CG33986 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\cbd-1, Cele\cpg-2, Cele\cpg-1, Cele\C39D10.7" - - - FBgn0260106 2L1668 - http://flybase.org/reports/FBgn0260106 gene - - - 2L1668 - - 11-Aug-17 DroID_v2017_08 - - - - - - "nucleus & terminal tracheal cell | somatic clone,embryonic/larval tracheal system,somatic clone" FBgn0004845 l(3)88Bc lethal (3) 88Bc http://flybase.org/reports/FBgn0004845 - gene - - - "l(3)M41, l(3)88Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266361 CR45009 - http://flybase.org/reports/FBgn0266361 non_protein_coding_gene - - - CR45009 - CR45009 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052676 stx stuxnet http://flybase.org/reports/FBgn0052676 protein_coding_gene - proteasomal ubiquitin-independent protein catabolic process ; GO:0010499 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CG9725, CG9732, CG32676, stx, stuxnet" "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG32676 11-Aug-17 DroID_v2017_08 "Drer\LOC100536600, Drer\midn" - - Xtro\midn Mmus\Midn Hsap\MIDN "viable,fertile,lethal,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0001593 l(1)carot10 lethal (1) carot10 http://flybase.org/reports/FBgn0001593 - gene - - - l(1)carot10 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267519 28SrRNA-Psi:CR45859 28S ribosomal RNA pseudogene:CR45859 http://flybase.org/reports/FBgn0267519 pseudogene_attribute - - - "CR45859, 28SrRNA-Psi:CR45859" - CR45859 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052058 Ir67c Ionotropic receptor 67c http://flybase.org/reports/FBgn0052058 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir67c, DmelIR67c, CG32058, IR67c" - CG32058 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,fertile" "chaeta,supernumerary,mesothoracic tergum" FBgn0004990 chr chrome http://flybase.org/reports/FBgn0004990 - gene - - - chr - - 11-Aug-17 DroID_v2017_08 - - - - - - "body color defective,recessive" FBgn0030014 CG15337 - http://flybase.org/reports/FBgn0030014 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15337 - CG15337 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030433 mRpL49 mitochondrial ribosomal protein L49 http://flybase.org/reports/FBgn0030433 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR001950 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q13405 translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR001950 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q13405 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "MRP-L49, CG4647, BcDNA:RE35556, mRpL49, mRpl49" "IPR001950:SUI1 domain, IPR007740:Ribosomal protein L49/IMG2" CG4647 11-Aug-17 DroID_v2017_08 Drer\mrpl49 Scer\IMG2 Cele\mrpl-49 - Mmus\Mrpl49 Hsap\MRPL49 FBgn0085519 CG40798 - http://flybase.org/reports/FBgn0085519 protein_coding_gene - - - CG40798 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065586 l(2)SH0911 lethal (2) SH0911 http://flybase.org/reports/FBgn0065586 gene - - - "l(2)SH0911, l(2)SH2 0911" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262618 Dif::Rel Dif::Rel http://flybase.org/reports/FBgn0262618 engineered_fusion_gene - - - "Dif::Rel, Dif^Rel" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030593 CG9512 - http://flybase.org/reports/FBgn0030593 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CT26924, CG9512, Dmel_CG9512" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9512 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0065141 l(3)SH105 lethal (3) SH105 http://flybase.org/reports/FBgn0065141 gene - - - "l(3)SH105, l(2)SH3 105" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265875 CR44664 - http://flybase.org/reports/FBgn0265875 non_protein_coding_gene - - - "lincRNA.1000, CR44664" - CR44664 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065627 l(2)SH0793 lethal (2) SH0793 http://flybase.org/reports/FBgn0065627 gene - - - "l(2)SH0793, l(2)SH2 0793" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000113 arch arch http://flybase.org/reports/FBgn0000113 - gene - - - arch - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0016039 mpl-1 male prothoracic leg 1 http://flybase.org/reports/FBgn0016039 - gene - - - "MPL-1, mpl-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062449 CG13197 - http://flybase.org/reports/FBgn0062449 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000340 protein dephosphorylation ; GO:0006470 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CG13197, BcDNA:RE27552" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR020422:Dual specificity protein phosphatase domain" CG13197 11-Aug-17 DroID_v2017_08 "Drer\dusp11, Drer\rngtt" Scer\CEG1 "Cele\pir-1, Cele\ptp-4, Cele\F54C8.4" "Xtro\dusp11.2, Xtro\rngtt" "Mmus\Dusp11, Mmus\Rngtt" "Hsap\DUSP11, Hsap\RNGTT, Hsap\DUSP23" viable FBgn0025788 anon-17Ae anon-17Ae http://flybase.org/reports/FBgn0025788 - gene - - - anon-17Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016813 l(1)L15 lethal (1) L15 http://flybase.org/reports/FBgn0016813 - gene - - - "l(1)L15, L15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067389 c601 c601 http://flybase.org/reports/FBgn0067389 gene - - - c601 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0051181 CG31181 - http://flybase.org/reports/FBgn0051181 protein_coding_gene - - - "BcDNA:GH06646, CG31181" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013664 ms(3)303 ms(3)303 http://flybase.org/reports/FBgn0013664 - gene - - - ms(3)303 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,male sterile" FBgn0035943 CG5653 - http://flybase.org/reports/FBgn0035943 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" - CG5653 "IPR002937:Amine oxidase, IPR023753:FAD/NAD(P)-binding domain" CG5653 11-Aug-17 DroID_v2017_08 "Drer\smox, Drer\paox1, Drer\si:dkey-275b16.2, Drer\zgc:66484" Scer\FMS1 "Cele\amx-3, Cele\amx-1, Cele\hpo-15" "Xtro\paox, Xtro\smox, Xtro\LOC100145496" "Mmus\Smox, Mmus\Kdm1b, Mmus\Paox" "Hsap\PAOX, Hsap\KDM1B, Hsap\SMOX" viable FBgn0032100 CG13108 - http://flybase.org/reports/FBgn0032100 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13108 - CG13108 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0021849 l(2)k14614 lethal (2) k14614 http://flybase.org/reports/FBgn0021849 - gene - - - l(2)k14614 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030704 CG15916 - http://flybase.org/reports/FBgn0030704 protein_coding_gene - rRNA processing ; GO:0006364 | inferred from electronic annotation with InterPro:IPR000238 - "BcDNA:RH08992, CG15916" "IPR015946:K homology domain-like, alpha/beta, IPR000238:Ribosome-binding factor A, IPR023799:Ribosome-binding factor A domain" CG15916 11-Aug-17 DroID_v2017_08 Drer\rbfa - Cele\C25G4.3 - Mmus\Rbfa Hsap\RBFA viable FBgn0001789 l(1)Mb8 lethal (1) Mb8 http://flybase.org/reports/FBgn0001789 - gene - - - l(1)Mb8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035571 CG12493 - http://flybase.org/reports/FBgn0035571 protein_coding_gene double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity siRNA binding ; GO:0035197 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "cg12493, CG12493" IPR014720:Double-stranded RNA-binding domain CG12493 11-Aug-17 DroID_v2017_08 "Drer\stau2, Drer\stau1" - Cele\stau-1 - "Mmus\Adarb1, Mmus\Stau1, Mmus\Stau2" "Hsap\ADARB1, Hsap\ADARB2, Hsap\STAU2, Hsap\STAU1" "viable,male fertile" FBgn0020365 anon-15ABa anon-15ABa http://flybase.org/reports/FBgn0020365 - gene - - - "548, anon-15ABa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267128 CR45568 - http://flybase.org/reports/FBgn0267128 non_protein_coding_gene - - - CR45568 - CR45568 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033206 DCTN4-p62 "Dynactin 4, p62 subunit" http://flybase.org/reports/FBgn0033206 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype nuclear migration ; GO:0007097 | inferred from biological aspect of ancestor with PANTHER:PTN000989859 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynactin complex ; GO:0005869 | inferred from biological aspect of ancestor with PANTHER:PTN000989859 cytoplasmic dynein complex ; GO:0005868 | inferred from biological aspect of ancestor with PANTHER:PTN000989859 dynactin complex ; GO:0005869 | inferred from sequence or structural similarity "CG12042, p62, DCTN4, DCTN4-p62, P62" IPR008603:Dynactin subunit 4 CG12042 11-Aug-17 DroID_v2017_08 Drer\dctn4 - Cele\dnc-4 Xtro\dctn4 Mmus\Dctn4 Hsap\DCTN4 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" FBgn0034094 Tsf3 Transferrin 3 http://flybase.org/reports/FBgn0034094 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR016357 "CG3666, Tsf3, tsf3" "IPR001156:Transferrin-like domain, IPR016357:Transferrin" CG3666 11-Aug-17 DroID_v2017_08 "Drer\otomp, Drer\mfi2, Drer\tfa, Drer\zgc:172271" - - "Xtro\tf, Xtro\mfi2, Xtro\depdc5" "Mmus\Trf, Mmus\Mfi2, Mmus\1300017J02Rik, Mmus\Ltf" "Hsap\TF, Hsap\LTF, Hsap\MELTF" "viable,locomotor rhythm defective" FBgn0032603 CG17928 - http://flybase.org/reports/FBgn0032603 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR012171 "lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804, InterPro:IPR012171 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012171 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001047707 "anon-WO0118547.16, CG17928" "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR005804:Fatty acid desaturase domain, IPR012171:Fatty acid desaturase" CG17928 11-Aug-17 DroID_v2017_08 "Drer\dpm3, Drer\fads2" - "Cele\fbxa-76, Cele\C24H12.1, Cele\fat-3, Cele\T27A1.3, Cele\fat-4, Cele\F49E11.8" "Xtro\dpm3, Xtro\fads2" "Mmus\4833423E24Rik, Mmus\Fads3, Mmus\Fads1, Mmus\Dpm3, Mmus\Fads2" "Hsap\FADS3, Hsap\FADS2, Hsap\FADS1, Hsap\DPM3" "viable,visible" "chaeta,supernumerary" FBgn0060518 l(3)S103414 lethal (3) S103414 http://flybase.org/reports/FBgn0060518 gene - - - "1034/14, l(3)S103414" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0262887 CR43242 - http://flybase.org/reports/FBgn0262887 non_protein_coding_gene - - - CR43242 - CR43242 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032124 CG17855 - http://flybase.org/reports/FBgn0032124 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17855 - CG17855 11-Aug-17 DroID_v2017_08 - Scer\RUD3 - Xtro\cttnbp2nl - Hsap\CTTNBP2NL viable FBgn0017545 RpS3A Ribosomal protein S3A http://flybase.org/reports/FBgn0017545 "FBgn0002630, FBgn0013757" protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001593, InterPro:IPR018281, InterPro:IPR027500 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001593, InterPro:IPR018281, InterPro:IPR027500 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001593, InterPro:IPR018281, InterPro:IPR027500 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement" "CG2168, RPS3A, M(4)101, RpS3a, RPS3a, clone 2.29, M57g, C3, M[57g], M(4)57g, M(4)[57g], l(4)102ABa, anon-EST:Liang-2.29, RpS3A, chr4:86830..87021, chr4:87101..87234, chr4:87503..87595, Rps3A, Rsp3A" "IPR018281:Ribosomal protein S3Ae, conserved site, IPR001593:Ribosomal protein S3Ae, IPR027500:40S ribosomal protein S1/3, eukaryotes" CG2168 11-Aug-17 DroID_v2017_08 Drer\rps3a "Scer\RPS1B, Scer\RPS1A" Cele\rps-1 Xtro\rps3a Mmus\Rps3a1 Hsap\RPS3A " embryonic stage | stage 1-11 , adult stage | male , embryonic stage&&larval stage , adult stage | female "

ubiquitous "developmental rate defective,dominant,visible,Minute,size defective,lethal - all die before end of larval stage,recessive,some die during larval stage,female sterile,heat sensitive,lethal" "macrochaeta,adult heart,adult,egg chamber,heat sensitive,nurse cell,follicle cell" DRSC17168 EK -1.086216543 -0.589509061 1.878426332 -2.574878617 0.835754937 3.25600388 FBgn0264427 CG43845 - http://flybase.org/reports/FBgn0264427 protein_coding_gene - - - "CR43845, CG43845" - CG43845 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038727 CG7432 - http://flybase.org/reports/FBgn0038727 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP19, c-SP19, CG7432" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG7432 11-Aug-17 DroID_v2017_08 "Drer\ela2, Drer\zgc:92745, Drer\si:dkey-57c15.4, Drer\ela3l, Drer\zgc:92511, Drer\zgc:112302, Drer\zgc:112285, Drer\ctrl, Drer\ctrb1, Drer\ela2l, Drer\LOC562139, Drer\zgc:171592, Drer\si:dkey-238d18.3, Drer\zgc:92041, Drer\zgc:112368, Drer\zgc:112160, Drer\zgc:154142" - "Cele\try-1, Cele\try-3, Cele\clec-4, Cele\svh-1" "Xtro\mst1, Xtro\cela2a, Xtro\cela3a, Xtro\LOC100135144, Xtro\ctrb2, Xtro\ctrb1" "Mmus\Cela3b, Mmus\Cela3a, Mmus\Cela2a, Mmus\Prss30, Mmus\Cela1, Mmus\Plg, Mmus\Tmprss15, Mmus\Ctrb1, Mmus\Ctrl, Mmus\Hgf, Mmus\Mst1, Mmus\Ctrc, Mmus\F2" "Hsap\CELA3B, Hsap\CTRB2, Hsap\MST1, Hsap\MST1L, Hsap\HGF, Hsap\CELA3A, Hsap\CTRC, Hsap\F2, Hsap\CELA2B, Hsap\CELA2A, Hsap\TMPRSS15, Hsap\PLAT, Hsap\CTRB1, Hsap\CELA1, Hsap\PLG, Hsap\CTRL" viable FBgn0085596 CG41280 - http://flybase.org/reports/FBgn0085596 protein_coding_gene - - - CG41280 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014080 anon-15Aa anon-15Aa http://flybase.org/reports/FBgn0014080 - gene - - - "gene x, anon-15Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065229 l(2)SH2184 lethal (2) SH2184 http://flybase.org/reports/FBgn0065229 gene - - - "l(2)SH2184, l(2)SH2 2184" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014223 l(2)31Eb lethal (2) 31Eb http://flybase.org/reports/FBgn0014223 - gene - - - l(2)31Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001241 hy humpy http://flybase.org/reports/FBgn0001241 - gene - - - hy - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced,female sterile,male sterile" adult thorax FBgn0038166 CG9588 - http://flybase.org/reports/FBgn0038166 protein_coding_gene - proteasome regulatory particle assembly ; GO:0070682 | inferred from biological aspect of ancestor with PANTHER:PTN000291528 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype "cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000291528 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000291528 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from biological aspect of ancestor with PANTHER:PTN000291528" "CG9588, 9588, dp27, p27" IPR001478:PDZ domain CG9588 11-Aug-17 DroID_v2017_08 Drer\psmd9 Scer\NAS2 Cele\psmd-9 Xtro\psmd9 Mmus\Psmd9 Hsap\PSMD9 viable FBgn0267470 CR45820 - http://flybase.org/reports/FBgn0267470 non_protein_coding_gene - - - CR45820 - CR45820 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060415 l(3)S129615 lethal (3) S129615 http://flybase.org/reports/FBgn0060415 gene - - - "1296/15, l(3)S129615" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040734 CG15065 - http://flybase.org/reports/FBgn0040734 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "defense response ; GO:0006952 | inferred from sequence or structural similarity with IM2, IM1" extracellular space ; GO:0005615 | inferred from sequence model "CT34936, IM2-like, CG15065" IPR013172:Immune-induced protein Dim CG15065 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265527 CR44377 - http://flybase.org/reports/FBgn0265527 non_protein_coding_gene - - - "CR44377, lincRNA.329" - CR44377 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037057 CG10512 - http://flybase.org/reports/FBgn0037057 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003767 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003767 - CG10512 IPR003767:Malate/L-lactate dehydrogenase CG10512 11-Aug-17 DroID_v2017_08 - - "Cele\VF13D12L.3, Cele\F36A2.3" - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0051706 CG31706 - http://flybase.org/reports/FBgn0051706 protein_coding_gene - - - "CG6528, CG31706" IPR032086:Protein of unknown function DUF4813 CG31706 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0028400 Syt4 Synaptotagmin 4 http://flybase.org/reports/FBgn0028400 protein_coding_gene "phosphatidylserine binding ; GO:0001786 | inferred from direct assay calcium-dependent phospholipid binding ; GO:0005544 | inferred from direct assay calcium-dependent phospholipid binding ; GO:0005544 | non-traceable author statement SNARE binding ; GO:0000149 | inferred from physical interaction with Snap25, Syx1A syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285" positive regulation of vesicle fusion ; GO:0031340 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 regulation of synaptic plasticity ; GO:0048167 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from mutant phenotype neuromuscular junction ; GO:0031594 | inferred from direct assay vesicle ; GO:0031982 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity postsynaptic membrane ; GO:0045211 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "Syt4, syt4, dsyt4, sytIV, SYT4, D.Syt IV, CG10047, SytIV, syt 4, Syt IV" "IPR000008:C2 domain, IPR001565:Synaptotagmin" CG10047 11-Aug-17 DroID_v2017_08 "Drer\syt10, Drer\si:ch211-266g18.6, Drer\syt17, Drer\syt11b, Drer\syt3, Drer\syt5a, Drer\syt11a, Drer\sytl5, Drer\syt5b, Drer\syt9b, Drer\pla2g4f.1, Drer\sytl1, Drer\pla2g4f.2, Drer\syt4, Drer\syt9a, Drer\tc2n, Drer\syt2a, Drer\sytl2a, Drer\syt1b" - Cele\snt-4 "Xtro\jmjd7-pla2g4b, Xtro\pla2g4f, Xtro\syt3, Xtro\syt4" "Mmus\Syt17, Mmus\Syt8, Mmus\Syt2, Mmus\Syt11, Mmus\Syt15, Mmus\Syt4, Mmus\Pla2g4e, Mmus\Sytl3, Mmus\Sytl2, Mmus\Syt9, Mmus\Tc2n, Mmus\Pla2g4d, Mmus\Pla2g4f, Mmus\Syt10, Mmus\Sytl4, Mmus\Pla2g4b, Mmus\Syt5" "Hsap\SYT9, Hsap\PLA2G4E, Hsap\SYTL2, Hsap\SYT17, Hsap\SYT4, Hsap\SYT5, Hsap\SYT2, Hsap\SYTL4, Hsap\SYTL3, Hsap\SYT16, Hsap\TC2N, Hsap\SYT10, Hsap\SYT7, Hsap\PLA2G4D, Hsap\PLA2G4F, Hsap\PLA2G4B, Hsap\SYT11, Hsap\SYT15, Hsap\SYT8" embryonic stage " neuron

, embryonic central nervous system

" adult stage neuron

"visible,neurophysiology defective,neuroanatomy defective,viable,fertile" "wing vein,neuromuscular junctionMhc.PW,NMJ bouton,neuromuscular junction,motor neuron,neuromuscular junctionrn16),neuromuscular junctionelav.PLu" FBgn0011609 l(1)I33d25 lethal (1) I33d25 http://flybase.org/reports/FBgn0011609 FBgn0010206 gene - - - "l(1)33d25, l(1)I33d25" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069300 agho aghino http://flybase.org/reports/FBgn0069300 gene - - - agho - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038269 Rrp6 Rrp6 http://flybase.org/reports/FBgn0038269 protein_coding_gene "3'-5' exonuclease activity ; GO:0008408 | inferred from electronic annotation with InterPro:IPR002562 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002121, InterPro:IPR002562, InterPro:IPR012337 nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR010997" defense response to virus ; GO:0051607 | inferred from mutant phenotype nuclear RNA surveillance ; GO:0071027 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000005527 inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG7292, dRrp6, Rrp6, DmRrp6, rrp6, RRP6" "IPR002121:HRDC domain, IPR002562:3'-5' exonuclease domain, IPR012337:Ribonuclease H-like domain, IPR012588:Exosome-associated factor Rrp6, N-terminal, IPR010997:HRDC-like" CG7292 11-Aug-17 DroID_v2017_08 Drer\exosc10 Scer\RRP6 "Cele\egal-1, Cele\crn-3" Xtro\exosc10 Mmus\Exosc10 Hsap\EXOSC10 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" DRSC16223 IE 3.429577469 0.542280039 2.092372413 -3.305690023 -1.276981611 0.64242152 FBgn0013472 l(1)11P11 lethal (1) 11P11 http://flybase.org/reports/FBgn0013472 - gene - - - l(1)11P11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg" FBgn0036934 sNPF-R short neuropeptide F receptor http://flybase.org/reports/FBgn0036934 protein_coding_gene neuropeptide Y receptor activity ; GO:0004983 | inferred from electronic annotation with InterPro:IPR000611 neuropeptide receptor activity ; GO:0008188 | inferred from direct assay neuropeptide receptor activity ; GO:0008188 | inferred from sequence model short neuropeptide F receptor activity ; GO:0036400 | inferred from physical interaction with sNPF "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000611 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of feeding behavior ; GO:2000253 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from genetic interaction with mir-9a positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CT22771, GPCR60, CG7395, Drm-sNPF-R, CG7395/CG18639, CG18639, anon-WO0131005.1, sNPF-R, sNPFR1, NPFR76F, Drm-NPFR76F, snpfr, sNPFR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000611:Neuropeptide Y receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG7395 11-Aug-17 DroID_v2017_08 "Drer\prlhr2a, Drer\gpr88, Drer\npy4r, Drer\prlhr2b, Drer\npy2r, Drer\mchr1b, Drer\npy1r, Drer\npy8ar, Drer\si:dkey-202l22.3, Drer\cmklr1, Drer\prokr1b, Drer\npy2rl, Drer\si:dkey-27p18.2, Drer\npy7r, Drer\gpr19, Drer\npy8br, Drer\prlh2r, Drer\c5ar1, Drer\mchr1a, Drer\hcrtr2, Drer\prokr1a, Drer\si:ch73-160i9.3" - "Cele\npr-17, Cele\npr-7, Cele\npr-22, Cele\npr-3, Cele\npr-2, Cele\npr-10, Cele\npr-6, Cele\npr-5, Cele\npr-4, Cele\npr-1, Cele\npr-13" "Xtro\prlhr, Xtro\LOC100497124" "Mmus\Fpr3, Mmus\Npy6r, Mmus\Prokr1, Mmus\Npy4r, Mmus\Gpr19, Mmus\Npy2r, Mmus\Gpr83, Mmus\Fpr1, Mmus\Fpr-rs3, Mmus\Hcrtr2, Mmus\Mchr1, Mmus\Npy5r, Mmus\Prokr2, Mmus\Npbwr1, Mmus\Gpr88, Mmus\Fpr2, Mmus\C3ar1, Mmus\Npy1r, Mmus\C5ar1, Mmus\Prlhr" "Hsap\NPY5R, Hsap\FPR1, Hsap\OPRPN, Hsap\GPR88, Hsap\NPY2R, Hsap\PROKR2, Hsap\GPR32, Hsap\GPR33, Hsap\HCRTR2, Hsap\GPR19, Hsap\FPR2, Hsap\MCHR1, Hsap\GPR83, Hsap\NPY4R, Hsap\C3AR1, Hsap\PROKR1, Hsap\NPY1R, Hsap\PRLHR, Hsap\CHRM4" "large body,feeding behavior defective,small body,viable" FBgn0039329 CG10669 - http://flybase.org/reports/FBgn0039329 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG10669 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG10669 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-119o8.6, Drer\LOC100332930, Drer\znf1035, Drer\znf1032, Drer\si:dkeyp-68b7.7, Drer\znf1004, Drer\znf1014, Drer\znf1003, Drer\zgc:66448, Drer\znf1007, Drer\znf648, Drer\znf1005, Drer\si:dkey-253d23.2, Drer\znf1124, Drer\znf1023, Drer\znf989, Drer\znf1015, Drer\LOC100332443, Drer\si:ch211-266d19.4, Drer\znf1002, Drer\LOC100534814, Drer\znf1034, Drer\znf1001, Drer\si:ch211-261d7.6" - "Cele\zfp-2, Cele\che-1, Cele\Y55F3AM.14, Cele\Y48G8AL.10" Xtro\znf470 "Mmus\Zfp62, Mmus\Zfp628, Mmus\Gm13212, Mmus\Zfp40, Mmus\Zfp11, Mmus\2610008E11Rik, Mmus\Zfp729a, Mmus\Zfp473, Mmus\Zfp648, Mmus\Zfp945" "Hsap\ZFP62, Hsap\ZNF628, Hsap\ZNF845, Hsap\ZNF681, Hsap\ZNF485, Hsap\ZNF721, Hsap\ZNF808, Hsap\ZNF648, Hsap\ZNF226, Hsap\ZNF493" "viable,fertile" FBgn0261998 CG42816 - http://flybase.org/reports/FBgn0261998 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 "CG42816, CG32186, CG5587, CG5944" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR026082:ABC transporter A, ABCA" CG42816 11-Aug-17 DroID_v2017_08 "Drer\abca5, Drer\abca1b, Drer\abch1, Drer\abca3b, Drer\abca2, Drer\abca12, Drer\abca1a" - "Cele\abt-1, Cele\abt-2, Cele\ced-7, Cele\abt-5, Cele\abt-4" "Xtro\abca8, Xtro\abca10, Xtro\abca9, Xtro\abca2, Xtro\abca4, Xtro\abca1, Xtro\abca3" "Mmus\Abca14, Mmus\Abca13, Mmus\Abca9, Mmus\Abca1, Mmus\Abca7, Mmus\Abca2, Mmus\Abca8b, Mmus\Abca17, Mmus\Abca15, Mmus\Abca8a, Mmus\Abca6, Mmus\Abca3, Mmus\Abca16, Mmus\Abca5, Mmus\Abca4, Mmus\Abca12" "Hsap\ABCA12, Hsap\ABCA8, Hsap\ABCA10, Hsap\ABCA3, Hsap\ABCA13, Hsap\ABCA6, Hsap\ABCA4, Hsap\ABCA2, Hsap\ABCA5, Hsap\ABCA9, Hsap\ABCA1, Hsap\ABCA7" FBgn0035815 Snmp2 Sensory neuron membrane protein 2 http://flybase.org/reports/FBgn0035815 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "148358_at, CG16832, Snmp2, SNMP2, CG7422" IPR002159:CD36 family CG7422 11-Aug-17 DroID_v2017_08 "Drer\scarb1, Drer\cd36, Drer\scarb2, Drer\LOC564077" - "Cele\scav-6, Cele\scav-4, Cele\scav-3, Cele\scav-2, Cele\scav-1, Cele\scav-5" "Xtro\cd36, Xtro\scarb2, Xtro\scarb1" "Mmus\Scarb1, Mmus\Scarb2, Mmus\Cd36" "Hsap\SCARB1, Hsap\CD36, Hsap\SCARB2" viable FBgn0046633 anon-38E.24 anon-38E.24 http://flybase.org/reports/FBgn0046633 gene - - - "38E.24, anon-38E.24" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005470 l(1)ts455b lethal (1) ts455b http://flybase.org/reports/FBgn0005470 - gene - - - l(1)ts455b - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030202 CG12640 - http://flybase.org/reports/FBgn0030202 protein_coding_gene - - - CG12640 - CG12640 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0004487 l(1)air14 lethal aberrant immune response 14 http://flybase.org/reports/FBgn0004487 - gene - - - l(1)air14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,melanotic mass,embryonic/larval lymph gland" FBgn0260033 siren7 siren 7 http://flybase.org/reports/FBgn0260033 gene - - - siren7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0032863 Cdc23 Cell division cycle 23 http://flybase.org/reports/FBgn0032863 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype endomitotic cell cycle ; GO:0007113 | inferred from mutant phenotype positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype anaphase-promoting complex ; GO:0005680 | inferred from physical interaction with APC7 "CG2508, 38C.54, CG2508-PA, cdc23, Apc8, Cdc23, APC8, CDC23" "IPR007192:Cdc23, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG2508 11-Aug-17 DroID_v2017_08 Drer\cdc23 Scer\CDC23 Cele\mat-3 Xtro\cdc23 Mmus\Cdc23 Hsap\CDC23 "lethal,mitotic cell cycle defective,increased cell death,endomitotic cell cycle defective,somatic clone,neuroanatomy defective,viable,fertile" "melanotic mass | third instar larval stage,nucleus | somatic clone,embryonic/larval neuroblast,ganglion mother cell" DRSC02708 I 2.692322675 1.116932439 0.602494993 -0.636278521 0.082502712 -0.581288585 FBgn0037101 CG7634 - http://flybase.org/reports/FBgn0037101 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7634 IPR011990:Tetratricopeptide-like helical domain CG7634 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014292 l(3)64Bc lethal (3) 64Bc http://flybase.org/reports/FBgn0014292 - gene - - - l(3)64Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259916 CG42445 - http://flybase.org/reports/FBgn0259916 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42445, CG7498" - CG42445 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262334 mir-992 mir-992 stem loop http://flybase.org/reports/FBgn0262334 miRNA_gene - - - "dme-mir-992, mir-992, CR43041, miR-992" - CR43041 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,lethal - all die before end of P-stage,some die during pharate adult stage" "eye,wing" FBgn0015406 l(1)12Ba lethal (1) 12Ba http://flybase.org/reports/FBgn0015406 - gene - - - l(1)12Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037150 CG7133 - http://flybase.org/reports/FBgn0037150 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001180323 CG7133 IPR001623:DnaJ domain CG7133 11-Aug-17 DroID_v2017_08 "Drer\dnajc30b, Drer\dnajc5gb, Drer\dnajc5ab, Drer\dnaja2l, Drer\dnajc30, Drer\dnaja1, Drer\dnajc5ga, Drer\dnajc5aa, Drer\dnaja2, Drer\dnajc5b" "Scer\XDJ1, Scer\YDJ1, Scer\ERJ5, Scer\JJJ2, Scer\CWC23, Scer\HLJ1, Scer\APJ1, Scer\SCJ1" "Cele\dnj-26, Cele\dnj-14, Cele\dnj-4" "Xtro\dnaja4.1, Xtro\dnaja2, Xtro\dnaja1, Xtro\dnaja4.2, Xtro\dnajc5g" "Mmus\Dnaja4, Mmus\Dnajc5g, Mmus\Dnajc5, Mmus\Dnajc30, Mmus\Dnaja1, Mmus\Dnajc5b, Mmus\Dnaja2" "Hsap\DNAJA2, Hsap\DNAJA4, Hsap\DNAJC5, Hsap\DNAJC30, Hsap\DNAJA1, Hsap\DNAJC5G, Hsap\DNAJC5B" viable FBgn0265216 fs(2)Z2-2984 - http://flybase.org/reports/FBgn0265216 gene - - - fs(2)Z2-2984 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0030797 CG13004 - http://flybase.org/reports/FBgn0030797 protein_coding_gene - - - CG13004 - CG13004 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0005523 l(2)52Dc lethal (2) 52Dc http://flybase.org/reports/FBgn0005523 - gene - - - l(2)52Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267662 CR46000 - http://flybase.org/reports/FBgn0267662 non_protein_coding_gene - - - CR46000 - CR46000 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086669 snoRNA:Psi18S-841a snoRNA:Psi18S-841a http://flybase.org/reports/FBgn0086669 snoRNA_gene - - - "snoRNA:66, psi18S-841a, Dm-66, snoR66, CR33765, Psi 18S-841a(SnoR66), Psi18S-841a, snoRNA:Psi18S-841a, psi-18S-841a" - CR33765 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036235 CG6938 - http://flybase.org/reports/FBgn0036235 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR032394 intracellular calcium activated chloride channel activity ; GO:0005229 | inferred from sequence or structural similarity with HGNC:27337 chloride transport ; GO:0006821 | inferred from sequence or structural similarity with HGNC:27337 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:27337 CG6938 "IPR007632:Anoctamin, IPR032394:Anoctamin, dimerisation domain" CG6938 11-Aug-17 DroID_v2017_08 "Drer\ano5a, Drer\ano11, Drer\LOC562630, Drer\LOC101886340, Drer\si:dkey-83h2.5, Drer\ano8b, Drer\ano9b, Drer\LOC103910000, Drer\ano6, Drer\ano8a, Drer\LOC101886884, Drer\ano9a, Drer\ano5b, Drer\LOC563500, Drer\ano2, Drer\ano1, Drer\ano3" Scer\IST2 "Cele\anoh-1, Cele\anoh-2" "Xtro\ano3, Xtro\ano2, Xtro\ano9, Xtro\ano1, Xtro\ano5" "Mmus\Ano8, Mmus\Ano5, Mmus\Ano9, Mmus\Ano6, Mmus\Ano3, Mmus\Ano2, Mmus\Ano7, Mmus\Ano4, Mmus\Ano1" "Hsap\ANO9, Hsap\ANO1, Hsap\ANO4, Hsap\ANO5, Hsap\ANO2, Hsap\ANO8, Hsap\ANO3, Hsap\ANO7, Hsap\ANO6" viable FBgn0263595 CR43617 - http://flybase.org/reports/FBgn0263595 non_protein_coding_gene - - - "CR43617, Dm_3R:69251" - CR43617 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030222 CG9806 - http://flybase.org/reports/FBgn0030222 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 extracellular region ; GO:0005576 | inferred from sequence model cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 CG9806 "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG9806 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-106j24.1, Drer\anpepb, Drer\si:ch211-198g19.1, Drer\si:ch211-276a23.5, Drer\lnpep, Drer\erap1b, Drer\erap1a, Drer\erap2, Drer\enpep, Drer\anpepa, Drer\si:ch211-149p5.1, Drer\npepps" "Scer\AAP1, Scer\TMA108, Scer\APE2" "Cele\R03G8.4, Cele\VB0395L.1, Cele\T16G12.1, Cele\R03G8.6, Cele\Y67D8C.9, Cele\AC3.5, Cele\F49B2.6, Cele\Y42A5A.1, Cele\T12E12.6, Cele\pam-1, Cele\T07F10.1, Cele\Y53F4B.20, Cele\mnp-1" "Xtro\npepps, Xtro\lnpep, Xtro\erap1, Xtro\lvrn, Xtro\anpep, Xtro\enpep" "Mmus\Npepps, Mmus\Lvrn, Mmus\Enpep, Mmus\Erap1, Mmus\Trhde, Mmus\Lnpep, Mmus\Anpep" "Hsap\LVRN, Hsap\NPEPPS, Hsap\ANPEP, Hsap\TRHDE, Hsap\ERAP2, Hsap\LNPEP, Hsap\ENPEP, Hsap\ERAP1" "viable,visible" trichogen cell FBgn0028628 ksh-19 ksh-19 http://flybase.org/reports/FBgn0028628 gene - - - ksh-19 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034329 IM1 Immune induced molecule 1 http://flybase.org/reports/FBgn0034329 protein_coding_gene - defense response ; GO:0006952 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay "CG18108, DIM-1, IM2-like, DIM 1, BcDNA:RH08745, IM1" IPR013172:Immune-induced protein Dim CG18108 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0040157 l(1)G0459 lethal (1) G0459 http://flybase.org/reports/FBgn0040157 gene - - - l(1)G0459 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,female sterile" FBgn0019903 anon-14Bg anon-14Bg http://flybase.org/reports/FBgn0019903 - gene - - - "ORF, anon-14Bg" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259528 B0097 - http://flybase.org/reports/FBgn0259528 gene - - - B0097 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0045032 usp::Cten\Usp-1 Usp-1 http://flybase.org/reports/FBgn0045032 engineered_fusion_gene - - - usp::Cten\Usp-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0001066 Fs(3)Tev Female sterile (3) Tevel http://flybase.org/reports/FBgn0001066 - gene - - - "Fs(3)Tevel, Fs(3)Sz21, Fs(3)Tev" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0002937 ninaB neither inactivation nor afterpotential B http://flybase.org/reports/FBgn0002937 FBgn0038171 protein_coding_gene "retinal isomerase activity ; GO:0004744 | inferred from direct assay beta-carotene 15,15'-monooxygenase activity ; GO:0003834 | inferred from direct assay inferred from mutant phenotype carotenoid dioxygenase activity ; GO:0010436 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from direct assay vitamin A biosynthetic process ; GO:0035238 | inferred from direct assay inferred from mutant phenotype vitamin biosynthetic process ; GO:0009110 | inferred from mutant phenotype carotene metabolic process ; GO:0016119 | inferred from direct assay rhodopsin biosynthetic process ; GO:0016063 | inferred from direct assay phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype phototransduction, UV ; GO:0007604 | inferred from mutant phenotype phototransduction ; GO:0007602 | traceable author statement retinal metabolic process ; GO:0042574 | inferred from direct assay" - "RPE65, beta-diox, anon-WO0148162.1, anon-WO0148163.1, DRPE65, CG9347, ninaB" IPR004294:Carotenoid oxygenase CG9347 11-Aug-17 DroID_v2017_08 "Drer\bco1, Drer\bco1l, Drer\bco2a, Drer\bco2l, Drer\rpe65c, Drer\rpe65b, Drer\bco2b, Drer\rpe65a" - "Cele\bcmo-2, Cele\F49E10.2, Cele\bcmo-1" "Xtro\bco2, Xtro\rpe65, Xtro\LOC100487224" "Mmus\Bco1, Mmus\Bco2, Mmus\Rpe65" "Hsap\RPE65, Hsap\BCO1, Hsap\BCO2" "neurophysiology defective,courtship behavior defective,male,phototaxis defective,viable" "photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,eye,rhabdomere" FBgn0028163 l(3)S034305 lethal (3) S034305 http://flybase.org/reports/FBgn0028163 gene - - - "0343/05, l(3)S034305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262711 ifm(2)RS4 - http://flybase.org/reports/FBgn0262711 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0038285 CG6974 - http://flybase.org/reports/FBgn0038285 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026" - CG6974 "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG6974 11-Aug-17 DroID_v2017_08 "Drer\tll1, Drer\c6ast4, Drer\si:ch73-40a17.3, Drer\he1a, Drer\tnfaip6, Drer\npsn, Drer\LOC100003133, Drer\he1b, Drer\bmp1b, Drer\mep1a.2, Drer\he2, Drer\c6ast3, Drer\mep1b, Drer\c6ast1, Drer\LOC797085, Drer\bmp1a" - "Cele\nas-24, Cele\nas-38, Cele\nas-39, Cele\nas-7, Cele\nas-21, Cele\nas-28, Cele\nas-19, Cele\nas-9, Cele\nas-33, Cele\nas-6, Cele\toh-1, Cele\nas-10, Cele\nas-1, Cele\nas-22" "Xtro\LOC100492324, Xtro\accs, Xtro\cubn, Xtro\mep1b, Xtro\LOC100489456, Xtro\tnfaip6, Xtro\mep1a, Xtro\uvs.2, Xtro\bmp1, Xtro\tll1, Xtro\tll2" "Mmus\Tll2, Mmus\Astl, Mmus\Mep1b, Mmus\Tnfaip6, Mmus\Adgrg6, Mmus\Tll1, Mmus\Mep1a, Mmus\Bmp1, Mmus\Cubn" "Hsap\ASTL, Hsap\TNFAIP6, Hsap\TLL2, Hsap\MEP1A, Hsap\TLL1, Hsap\ADGRG6, Hsap\CUBN, Hsap\MEP1B, Hsap\BMP1" viable FBgn0082687 E(ftz)1819 E(ftz)1819 http://flybase.org/reports/FBgn0082687 gene - - - "1819, E(ftz)1819" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040173 l(1)G0344 lethal (1) G0344 http://flybase.org/reports/FBgn0040173 gene - - - l(1)G0344 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0062676 EP2419 EP2419 http://flybase.org/reports/FBgn0062676 gene - - - "EP(2)2419, EP2419" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,ommatidium" FBgn0060519 l(3)S102908 lethal (3) S102908 http://flybase.org/reports/FBgn0060519 gene - - - "1029/08, l(3)S102908" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041631 HSE Heat shock element http://flybase.org/reports/FBgn0041631 regulatory_region - - - HSE - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035103 Vdup1 Vitamin D[[3]] up-regulated protein 1 http://flybase.org/reports/FBgn0035103 protein_coding_gene - negative regulation of gene expression ; GO:0010629 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "vdup1, dvdup1, VDUP1, Vdup1, CG7047" "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG7047 11-Aug-17 DroID_v2017_08 "Drer\arrdc1b, Drer\zgc:110626, Drer\LOC799768, Drer\arrdc3a, Drer\txnipb, Drer\zgc:110353, Drer\txnipa, Drer\arrdc2, Drer\arrdc1a, Drer\si:ch211-130m23.2, Drer\arrdc3b" "Scer\ALY2, Scer\ART5, Scer\ROD1, Scer\ROG3, Scer\ALY1, Scer\LDB19, Scer\CSR2, Scer\ECM21, Scer\RIM8" "Cele\arrd-27, Cele\arrd-25, Cele\arrd-6, Cele\arrd-8, Cele\arrd-13, Cele\arrd-18, Cele\arrd-5, Cele\arrd-22, Cele\arrd-14, Cele\arrd-19, Cele\arrd-7, Cele\arrd-11, Cele\arrd-4, Cele\arrd-10, Cele\arrd-1, Cele\arrd-15, Cele\arrd-16, Cele\arrd-3, Cele\arrd-12, Cele\arrd-2, Cele\rnh-1.2, Cele\arrd-24, Cele\arrd-23, Cele\arrd-9, Cele\arrd-17" "Xtro\arrdc2, Xtro\arrdc4, Xtro\arrdc3, Xtro\txnip" "Mmus\Txnip, Mmus\Arrdc2, Mmus\Arrdc3, Mmus\Arrdc5, Mmus\Arrdc4, Mmus\Arrdc1" "Hsap\ARRDC3, Hsap\TXNIP, Hsap\ARRDC4, Hsap\ARRDC1, Hsap\ARRDC5, Hsap\ARRDC2" viable FBgn0014070 Su(tor)3-91 Su(tor)3-91 http://flybase.org/reports/FBgn0014070 - gene - - - Su(tor)3-91 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036005 pall pallbearer http://flybase.org/reports/FBgn0036005 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "pall, CG3428, FBXO1, Pall, PALL" IPR001810:F-box domain CG3428 11-Aug-17 DroID_v2017_08 Drer\fbxo28 - "Cele\fbxa-66, Cele\ZC247.2" Xtro\fbxo28 Mmus\Fbxo28 Hsap\FBXO28 viable FBgn0015853 anon-10Cf anon-10Cf http://flybase.org/reports/FBgn0015853 - gene - - - anon-10Cf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039666 Diedel Diedel http://flybase.org/reports/FBgn0039666 protein_coding_gene cytokine activity ; GO:0005125 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from expression pattern negative regulation of JAK-STAT cascade ; GO:0046426 | traceable author statement extracellular space ; GO:0005615 | inferred from direct assay "BcDNA:RH38110, Diedel, CG11501, die, diedel" IPR025061:Diedel CG11501 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC14317 K 0.325148812 -0.317737346 0.171962994 0.517218706 -1.5835033 -1.148860884 FBgn0023430 l(3)69ABa lethal (3) 69ABa http://flybase.org/reports/FBgn0023430 - gene - - - l(3)69ABa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265951 CR44738 - http://flybase.org/reports/FBgn0265951 non_protein_coding_gene - - - "lincRNA.191, CR44738" - CR44738 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036990 mRpL15 mitochondrial ribosomal protein L15 http://flybase.org/reports/FBgn0036990 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AA128556 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AA128556 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AA128556 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "L15, CG5219, l(3)77CDc, mRpL15" "IPR005749:Ribosomal protein L15, bacterial-type, IPR030878:Ribosomal protein L15, IPR021131:Ribosomal protein L18e/L15P" CG5219 11-Aug-17 DroID_v2017_08 Drer\mrpl15 Scer\MRPL10 Cele\mrpl-15 Xtro\mrpl15 Mmus\Mrpl15 Hsap\MRPL15 "wild-type,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,visible" trichogen cell FBgn0039609 CG14529 - http://flybase.org/reports/FBgn0039609 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG14529 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG14529 11-Aug-17 DroID_v2017_08 "Drer\ece2b, Drer\mmel1, Drer\phex, Drer\ece1" - "Cele\nep-16, Cele\nep-26, Cele\nep-13, Cele\nep-9, Cele\nep-7, Cele\nep-10, Cele\nep-21, Cele\nep-3, Cele\nep-6, Cele\nep-19, Cele\nep-20, Cele\nep-18, Cele\nep-24, Cele\nep-8, Cele\nep-17, Cele\nep-5, Cele\nep-23, Cele\nep-12" "Xtro\mmel1, Xtro\ece1, Xtro\ece2, Xtro\ecel1" "Mmus\Ecel1, Mmus\Mme, Mmus\Phex, Mmus\Ece1, Mmus\Mmel1, Mmus\Kel, Mmus\Ece2" "Hsap\KEL, Hsap\MMEL1, Hsap\MME, Hsap\PHEX, Hsap\ECE1, Hsap\ECEL1, Hsap\ECE2" viable FBgn0024910 anon-16Fb anon-16Fb http://flybase.org/reports/FBgn0024910 - gene - - - "F-d, anon-16Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028225 l(3)S005343 lethal (3) S005343 http://flybase.org/reports/FBgn0028225 gene - - - "0053/43, l(3)S005343" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015415 l(1)15DFa lethal (1) 15DFa http://flybase.org/reports/FBgn0015415 - gene - - - l(1)15DFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005253 l(3)SG72 lethal (3) SG72 http://flybase.org/reports/FBgn0005253 - gene - - - l(3)SG72 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005080 fs(2)OW804 female sterile (2) OW804 http://flybase.org/reports/FBgn0005080 - gene - - - fs(2)OW804 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038527 CG14324 - http://flybase.org/reports/FBgn0038527 protein_coding_gene - - - "BcDNA:RE34075, CG14324" - CG14324 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065964 l(2)SH0023 lethal (2) SH0023 http://flybase.org/reports/FBgn0065964 gene - - - l(2)SH0023 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013505 l(1)R lethal (1) R http://flybase.org/reports/FBgn0013505 - gene - - - l(1)R - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013659 ms(2)neo4 ms(2)neo4 http://flybase.org/reports/FBgn0013659 - gene - - - ms(2)neo4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,male semi-sterile,recessive" FBgn0001032 Fs(3)Bot Female sterile (3) Botond http://flybase.org/reports/FBgn0001032 - gene molecular_function ; GO:0003674 | no biological data available embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Bot, Fs(3)Botond, Fs(3)Sz6, Fs(3)Bot" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0265459 Pten::Hsap\PTEN - http://flybase.org/reports/FBgn0265459 engineered_fusion_gene - - - Pten::Hsap\PTEN - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,ommatidium" FBgn0082600 barfly barfly http://flybase.org/reports/FBgn0082600 gene - behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype - "barfly, brf, F48" - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0060946 l(3)S037913 lethal (3) S037913 http://flybase.org/reports/FBgn0060946 gene - - - "0379/13, l(3)S037913" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065268 l(2)SH2065 lethal (2) SH2065 http://flybase.net/reports/FBgn0065268.html gene l(2)SH2 2065 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0000639 Fbp1 Fat body protein 1 http://flybase.org/reports/FBgn0000639 - protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with UniProtKB:Q23810 inferred from sequence or structural similarity with protein_id:BAA06161.1 inferred from physical interaction with Lsp1α storage protein import into fat body ; GO:0015032 | inferred from sequence or structural similarity with UniProtKB:Q23810 inferred from sequence or structural similarity with protein_id:BAA06161.1 inferred from physical interaction with Lsp1α lipid particle ; GO:0005811 | inferred from direct assay "Fbp1, CG17285, fbp1, Fbp-1, fbp-1, P1, DmeFBP1, FBP1, LP07910p, FBP-1, FbP1" "IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set, IPR008922:Uncharacterised domain, di-copper centre" CG17285 11-Aug-17 DroID_v2017_08 - - "Cele\C49A9.2, Cele\C49A9.3, Cele\F58F9.4" - - - " prepupal stage , larval stage | third instar " "viable,visible" "chaeta,supernumerary" DRSC11166 IE -0.107803186 -2.742804636 -1.812833562 -0.040404357 -0.056758943 0.510452512 FBgn0019757 l(1)75B3 lethal (1) 75B3 http://flybase.org/reports/FBgn0019757 - gene - - - l(1)75B3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040793 CG7630 - http://flybase.org/reports/FBgn0040793 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay "anon-EST:Posey228, anon-EST:Posey153, BcDNA:RH19679, CG7630" IPR031973:Deltamethrin resistance protein prag01 CG7630 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell DRSC10895 I -1.446533134 -1.849959914 -1.306958193 -0.683119007 -0.341451225 1.495704406 FBgn0001389 l(1)2Bu lethal (1) 2Bu http://flybase.org/reports/FBgn0001389 - gene - - - "l(1)10-153-2, 10-153-2, l(1)2Bu" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052151 CG32151 - http://flybase.org/reports/FBgn0052151 protein_coding_gene - - - CG32151 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011135 l(1)Q210 lethal (1) Q210 http://flybase.org/reports/FBgn0011135 FBgn0010210 gene - - - l(1)Q210 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265106 CR44208 - http://flybase.org/reports/FBgn0265106 non_protein_coding_gene - - - CR44208 - CR44208 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053153 CG33153 - http://flybase.org/reports/FBgn0053153 protein_coding_gene - - - CG33153 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003676 CCT1 Chaperonin containing TCP1 subunit 1 http://flybase.org/reports/FBgn0003676 FBgn0043836 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012715 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 phagocytosis ; GO:0006909 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000144020 "T-cpl, gh05123, BEST:GH05123, Tcp-1, CG5374, T-cp1, tcp1, Tcp1, Tcp1-like, TCPA_DROME, CCT1, TCP-1alpha, Tcp1-alpha, TCP1alpha, T-CP1, TCP1-alpha, cct1" "IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012715:T-complex protein 1, alpha subunit, IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG5374 11-Aug-17 DroID_v2017_08 "Drer\mkks, Drer\cct7, Drer\bbs10, Drer\tcp1" Scer\TCP1 Cele\cct-1 "Xtro\cct7, Xtro\tcp1" "Mmus\Bbs10, Mmus\Mkks, Mmus\Cct7, Mmus\Tcp1" "Hsap\CCT7, Hsap\BBS10, Hsap\MKKS, Hsap\TCP1" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16877 E 1.426228757 -0.613398535 3.027004188 -0.751635585 -0.135714501 -0.566715079 FBgn0037464 CG1988 - http://flybase.org/reports/FBgn0037464 protein_coding_gene - - - CG1988 - CG1988 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0265727 CR44534 - http://flybase.org/reports/FBgn0265727 non_protein_coding_gene - - - "CR44534, lincRNA.972" - CR44534 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263887 l(3)D7 - http://flybase.org/reports/FBgn0263887 gene - - - l(3)D7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0011095 l(1)Q55 lethal (1) Q55 http://flybase.org/reports/FBgn0011095 FBgn0010210 gene - - - l(1)Q55 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001654 l(1)ds8 lethal (1) discs small 8 http://flybase.org/reports/FBgn0001654 - gene - - - "l(1)d sml-8, l(1)d.sml.-8, l(1)ds8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0002249 l(3)68Dc lethal (3) 68Dc http://flybase.org/reports/FBgn0002249 - gene - - - "rsg10, l(3)rsg10, l(3)68Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053468 CG33468 - http://flybase.org/reports/FBgn0053468 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33468 - CG33468 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267865 CR46153 - http://flybase.org/reports/FBgn0267865 non_protein_coding_gene - - - CR46153 - CR46153 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014845 E(var)2-88 Enhancer of variegation 2-88 http://flybase.org/reports/FBgn0014845 - gene - - - E(var)2-88 - - 11-Aug-17 DroID_v2017_08 - - - - - - enhancer of variegation FBgn0250826 CG34160 - http://flybase.org/reports/FBgn0250826 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34160, NEST:bs34b09" - CG34160 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267494 Mst77Y-8Psi Male-specific pseudogene 77Y 8 http://flybase.org/reports/FBgn0267494 pseudogene_attribute - - - "CR45774, Mst77Y-8Psi, Mst77Y-8" - CR45774 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065967 l(2)SH0008 lethal (2) SH0008 http://flybase.org/reports/FBgn0065967 gene - - - "l(2)SH0008, l(2)SH2 0008" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050106 CCHa1-R CCHamide-1 receptor http://flybase.org/reports/FBgn0050106 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from sequence model neuropeptide receptor activity ; GO:0008188 | inferred from direct assay allatostatin receptor activity ; GO:0008261 | inferred from direct assay allatostatin receptor activity ; GO:0008261 | NOT inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "CG14484, CG18192, CG30106, CCHa1-R, CCHa1r, CCHamide1r" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001556:Bombesin receptor-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG30106 11-Aug-17 DroID_v2017_08 "Drer\ednrba, Drer\si:ch211-119o8.4, Drer\grpr, Drer\ednrab, Drer\ednrbb, Drer\gpr37a, Drer\nmbr, Drer\gpr37b, Drer\si:dkey-42l23.4, Drer\gpr37l1a, Drer\ednraa, Drer\gpr37l1b" - Cele\npr-4 "Xtro\ednra, Xtro\ednrb, Xtro\gpr37, Xtro\brs3, Xtro\ednrb2, Xtro\grpr" "Mmus\Mrgpre, Mmus\Mrgprh, Mmus\Mrgprg, Mmus\Mrgprb8, Mmus\Grpr, Mmus\Mrgprb2, Mmus\Ednra, Mmus\Mrgpra5, Mmus\Gpr151, Mmus\Mrgpra4, Mmus\Mrgpra9, Mmus\Mrgprx1, Mmus\Gpr37, Mmus\Ednrb, Mmus\Mrgpra2a, Mmus\Gpr37l1, Mmus\Mrgpra7, Mmus\Mrgprb5, Mmus\Brs3, Mmus\Mrgprx2, Mmus\Mrgprd, Mmus\Mrgprb3, Mmus\Mrgpra1, Mmus\Mrgpra3, Mmus\Mrgprb4, Mmus\Mrgpra8, Mmus\Nmbr, Mmus\Mrgprf, Mmus\Mrgpra6, Mmus\Mas1, Mmus\Mrgprb1" "Hsap\MRGPRG, Hsap\MRGPRE, Hsap\GRPR, Hsap\MRGPRX3, Hsap\GPR151, Hsap\MAS1L, Hsap\MRGPRX4, Hsap\BRS3, Hsap\NMBR, Hsap\MAS1, Hsap\MRGPRX1, Hsap\EDNRB, Hsap\GPR37, Hsap\MRGPRF, Hsap\EDNRA, Hsap\GPR37L1, Hsap\MRGPRD, Hsap\MRGPRX2" "viable,fertile" FBgn0046302 CG10650 - http://flybase.org/reports/FBgn0046302 protein_coding_gene - - - "BEST:GH09876, CG10650" IPR008472:Domain of unknown function DUF753 CG10650 11-Aug-17 DroID_v2017_08 - - Cele\M02G9.3 - - - "viable,fertile" FBgn0051295 CG31295 - http://flybase.org/reports/FBgn0051295 protein_coding_gene - - - "BcDNA:SD17750, CG31295" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065787 l(2)SH0433 lethal (2) SH0433 http://flybase.org/reports/FBgn0065787 gene - - - "l(2)SH0433, l(2)SH2 0433" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0042111 CG18766 - http://flybase.org/reports/FBgn0042111 protein_coding_gene - - - "CG5995, CG18766" IPR026095:Myb/SANT-like DNA-binding domain-containing protein CG18766 11-Aug-17 DroID_v2017_08 Drer\msantd1 - - - Mmus\Msantd1 Hsap\MSANTD1 viable FBgn0034142 CG8306 - http://flybase.org/reports/FBgn0034142 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 long-chain-fatty-acyl-CoA reductase activity ; GO:0050062 | inferred from sequence or structural similarity with UniProtKB:Q922J9 wax biosynthetic process ; GO:0010025 | inferred from sequence or structural similarity with UniProtKB:Q922J9 endomembrane system ; GO:0012505 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence or structural similarity with UniProtKB:Q922J9 CG8306 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG8306 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" - "Cele\fard-1, Cele\F13D11.4" Xtro\far1 "Mmus\Far2, Mmus\Far1, Mmus\Hsd3b1" "Hsap\FAR2, Hsap\FAR1" lethal FBgn0013474 l(1)12P3 lethal (1) 12P3 http://flybase.org/reports/FBgn0013474 - gene - - - l(1)12P3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0265342 CG44296 - http://flybase.org/reports/FBgn0265342 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000329966 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000329966" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000329966 CG44296 IPR004202:Cytochrome c oxidase subunit VIIc CG44296 11-Aug-17 DroID_v2017_08 Drer\cox7c Scer\COX8 Cele\F26E4.6 Xtro\cox7c Mmus\Cox7c Hsap\COX7C FBgn0020263 oro oroshigane http://flybase.org/reports/FBgn0020263 FBgn0015693 gene - - - "E(B)2A, oro" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/first instar larval cuticle,egg" FBgn0002574 lys lysine http://flybase.org/reports/FBgn0002574 - gene - - - lys - - 11-Aug-17 DroID_v2017_08 - - - - - - fat body FBgn0014455 Ahcy Adenosylhomocysteinase http://flybase.org/reports/FBgn0014455 - protein_coding_gene NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR000043 adenosylhomocysteinase activity ; GO:0004013 | inferred from biological aspect of ancestor with PANTHER:PTN000602759 adenosylhomocysteinase activity ; GO:0004013 | inferred from sequence or structural similarity with EMBL:U18796 inferred from sequence or structural similarity with protein_id:AAA51682 inferred from sequence or structural similarity with protein_id:AAB25906 "one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR000043, InterPro:IPR020082 S-adenosylhomocysteine catabolic process ; GO:0019510 | inferred from electronic annotation with InterPro:IPR000043 S-adenosylmethionine cycle ; GO:0033353 | inferred from biological aspect of ancestor with PANTHER:PTN000602759" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000602759 "CG11654, ahcY, SAHH, Ahcy13, Ahcy" "IPR000043:Adenosylhomocysteinase-like, IPR015878:S-adenosyl-L-homocysteine hydrolase, NAD binding domain, IPR020082:S-adenosyl-L-homocysteine hydrolase, conserved site, IPR034373:Adenosylhomocysteinase, IPR016040:NAD(P)-binding domain" CG11654 11-Aug-17 DroID_v2017_08 "Drer\zgc:158222, Drer\ahcyl1, Drer\ahcy, Drer\ahcyl2" Scer\SAH1 Cele\ahcy-1 "Xtro\ahcyl2, Xtro\ahcyl1, Xtro\ahcy" "Mmus\Ahcyl2, Mmus\Ahcy, Mmus\Gm4737, Mmus\Ahcyl1" "Hsap\AHCYL1, Hsap\AHCY, Hsap\AHCYL2" embryonic stage -- adult stage viable FBgn0035008 CG3494 - http://flybase.org/reports/FBgn0035008 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype - "CT11751, CG3494" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG3494 11-Aug-17 DroID_v2017_08 "Drer\lrrc40, Drer\lrrc30a" - - "Xtro\LOC100487847, Xtro\lrrc40, Xtro\lrrc10b, Xtro\lrrc10" "Mmus\Lrrc40, Mmus\Lrrc30" "Hsap\LRRC40, Hsap\LRRC30" viable FBgn0264441 CR43859 - http://flybase.org/reports/FBgn0264441 non_protein_coding_gene - - - CR43859 - CR43859 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034674 CG9304 - http://flybase.org/reports/FBgn0034674 protein_coding_gene - G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR019336 response to pheromone ; GO:0019236 | inferred from electronic annotation with InterPro:IPR019336 - CG9304 "IPR019336:Intimal thickness related receptor, IRP" CG9304 11-Aug-17 DroID_v2017_08 "Drer\tmem145, Drer\gpr180" - "Cele\T04F8.2, Cele\C15A7.2" "Xtro\gpr180, Xtro\tmem145" "Mmus\Gpr180, Mmus\Tmem145" "Hsap\GPR180, Hsap\TMEM145" viable FBgn0011905 tRNA:Lys-TTT-2-5 transfer RNA:Lysine-TTT 2-5 http://flybase.org/reports/FBgn0011905 "FBgn0003793, FBgn0011901, FBgn0051197, FBgn0060171" tRNA_gene AAA codon-amino acid adaptor activity ; GO:0033443 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033443 cytosol ; GO:0005829 | inferred by curator from GO:0033443 "AE002708.trna3-LysTTT, tRNA:K5, tRNA:K:TTT:AE002708, CR31197, tRNA:lys5:87BC, chr3R.trna9-LysTTT, tRNA-Lys-TTT-2-5, tRNA:Lys-TTT-2-5, tRNA:K5:87BC, AAA" - CR31197 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016849 l(1)N30 lethal (1) N30 http://flybase.org/reports/FBgn0016849 - gene - - - "l(1)N30, N30" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002607 RpL19 Ribosomal protein L19 http://flybase.org/reports/FBgn0002607 "FBgn0010030, FBgn0022215, FBgn0025292" protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000196, InterPro:IPR015972, InterPro:IPR015974 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" cytosolic large ribosomal subunit ; GO:0022625 | inferred from electronic annotation with InterPro:IPR033935 cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "rpl19, l(2)k03704, rpL19, M(2)60E, E(Dl)KP135, L19, M(2)c, anon-EST:Posey33, M(2)a, CG2746, RpL19, M60E, Rp L19, Rpl19, RPL19" "IPR015972:Ribosomal protein L19/L19e, domain 1, IPR015974:Ribosomal protein L19/L19e, domain 3, IPR000196:Ribosomal protein L19/L19e, IPR033935:Ribosomal protein L19, eukaryotic, IPR015973:Ribosomal protein L19/L19e, domain 2, IPR023638:Ribosomal protein L19/L19e conserved site" CG2746 11-Aug-17 DroID_v2017_08 Drer\rpl19 "Scer\RPL19A, Scer\RPL19B" Cele\rpl-19 Xtro\rpl19 Mmus\Rpl19 Hsap\RPL19 "lethal,recessive,visible,dominant,developmental rate defective,viable" macrochaeta DRSC04649 IEK -2.445740034 -1.638076225 0.659973874 -2.036295371 2.776347035 3.735108756 FBgn0001630 l(1)dn7 lethal (1) discs normal 7 http://flybase.org/reports/FBgn0001630 - gene - - - "l(1)d.norm.-7, l(1)dn7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030207 CG2887 - http://flybase.org/reports/FBgn0030207 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR008971 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971 - CG2887 "IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site" CG2887 11-Aug-17 DroID_v2017_08 "Drer\dnajb5, Drer\dnajb1b, Drer\dnajb4, Drer\dnajb2, Drer\zgc:122979, Drer\dnajc22, Drer\dnajb1a" "Scer\SIS1, Scer\JJJ1, Scer\APJ1, Scer\JJJ3, Scer\JJJ2, Scer\ERJ5, Scer\SCJ1" "Cele\F54F2.9, Cele\dnj-19, Cele\dnj-22, Cele\dnj-12, Cele\dnj-13, Cele\dnj-1" "Xtro\dnajb4, Xtro\dnajb1, Xtro\dnajb5" "Mmus\4930503B20Rik, Mmus\Dnajb5, Mmus\Dnajc22, Mmus\Dnajb4, Mmus\Dnajb1" "Hsap\DNAJB5, Hsap\DNAJB1, Hsap\DNAJB4, Hsap\DNAJC22" viable FBgn0014981 l(2)46Cb lethal (2) 46Cb http://flybase.org/reports/FBgn0014981 - gene - - - "II, l(2)46Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0001220 Hsc70-5 Heat shock protein cognate 5 http://flybase.org/reports/FBgn0001220 FBgn0022196 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012725 unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P38646 positive regulation of mitochondrial membrane potential ; GO:0010918 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P38646 microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P38646 "Hsc70-5, Hsc70, HSC-70, HSC70, Hsc5, l(2)k04907, hsc70, dhsc70, HSC5, CG8542, hsc-70-5, Hsc-5, HSC70-5, hsc70-5, Hsp-c5, hsc5" "IPR018181:Heat shock protein 70, conserved site, IPR012725:Chaperone DnaK, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG8542 11-Aug-17 DroID_v2017_08 Drer\hspa9 "Scer\ECM10, Scer\SSQ1, Scer\SSC1" Cele\hsp-6 Xtro\hspa9 Mmus\Hspa9 Hsap\HSPA9 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,majority die during pupal stage,short lived,temperature conditional,locomotor rhythm defective,progressive,majority die during second instar larval stage,viable,majority die during third instar larval stage" mitochondrion DRSC07442 I -2.417277797 0.141278778 -0.61489733 -0.064526791 0.290182729 -0.38384767 FBgn0037301 Mms19 Mms19 http://flybase.org/reports/FBgn0037301 protein_coding_gene - - - "dMMS19, NEST:bs07f08, CG12005, Mms19, MMS19, mms19" "IPR016024:Armadillo-type fold, IPR024687:MMS19, C-terminal, IPR011989:Armadillo-like helical" CG12005 11-Aug-17 DroID_v2017_08 Drer\mms19 Scer\MET18 Cele\mms-19 Xtro\mms19 Mmus\Mms19 Hsap\MMS19 "lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0038598 CG7131 - http://flybase.org/reports/FBgn0038598 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR033336 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.212, CG7131" IPR033336:Stabilizer of axonemal microtubules 1/2 CG7131 11-Aug-17 DroID_v2017_08 Drer\saxo2 - "Cele\H03A11.2, Cele\T08G11.3, Cele\H13N06.7" Xtro\saxo2 "Mmus\Saxo1, Mmus\Saxo2" "Hsap\SAXO2, Hsap\SAXO1" FBgn0001221 Hsc70-6 Heat shock protein cognate 6 http://flybase.org/reports/FBgn0001221 - gene - - - "Hsc70, HSC-70, HSC70, hsc6, hsc70, dhsc70, Hsc6, Hsc70-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067872 Mod(Prat:bw)3-3 Mod(Prat:bw)3-3 http://flybase.org/reports/FBgn0067872 gene - - - "Mod-3-3, Mod(Prat:bw)3-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001701 l(1)ESHS22 lethal (1) ESHS22 http://flybase.org/reports/FBgn0001701 - gene - - - l(1)ESHS22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266211 CR44906 - http://flybase.org/reports/FBgn0266211 pseudogene_attribute - - - CR44906 - CR44906 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051778 CG31778 - http://flybase.org/reports/FBgn0051778 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "BcDNA:HL03084, CG31778" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG31778 11-Aug-17 DroID_v2017_08 Drer\chtf18 Scer\CTF18 - Xtro\chtf18 Mmus\Chtf18 Hsap\CHTF18 viable FBgn0260324 GSd327 - http://flybase.org/reports/FBgn0260324 gene - - - GSd327 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263512 Vsx2 Visual system homeobox 2 http://flybase.org/reports/FBgn0263512 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:1975" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:1975 optic lobe placode development ; GO:0001748 | inferred from expression pattern - "CG33980, Vsx2, Chx2, CG15783, CG15782, CG15781, dVsx2, DChx2, dChx2" "IPR023339:CVC domain, IPR001356:Homeobox domain, IPR003654:OAR domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site" CG33980 11-Aug-17 DroID_v2017_08 "Drer\alx4a, Drer\arxa, Drer\alx3, Drer\rx2, Drer\rx1, Drer\alx1, Drer\vsx1, Drer\vsx2" - "Cele\dsc-1, Cele\ceh-10" "Xtro\alx4, Xtro\alx1, Xtro\arx, Xtro\vsx2, Xtro\vsx1" "Mmus\Alx3, Mmus\Alx4, Mmus\Vsx2, Mmus\Vsx1, Mmus\Arx" "Hsap\ARX, Hsap\VSX2, Hsap\VSX1, Hsap\ALX4, Hsap\ALX3, Hsap\ALX1" FBgn0010120 l(1)2Dc lethal (1) 2Dc http://flybase.org/reports/FBgn0010120 - gene - - - "l(1)405, l(1)2Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033573 Obp47a Odorant-binding protein 47a http://flybase.org/reports/FBgn0033573 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "47a, CG12944, Obp47a, DmelObp47a" IPR006170:Pheromone/general odorant binding protein CG12944 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000067 ale almond eye http://flybase.org/reports/FBgn0000067 - gene - - - ale - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" eye FBgn0030958 CR6900 - http://flybase.org/reports/FBgn0030958 pseudogene_attribute - - - "CG6900, CR6900" - CR6900 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033052 SCAP SREBP cleavage activating protein http://flybase.org/reports/FBgn0033052 protein_coding_gene cholesterol binding ; GO:0015485 | inferred from electronic annotation with InterPro:IPR030225 SREBP signaling pathway ; GO:0032933 | inferred from electronic annotation with InterPro:IPR030225 cholesterol metabolic process ; GO:0008203 | inferred from electronic annotation with InterPro:IPR030225 sterol regulatory element binding protein cleavage ; GO:0035103 | non-traceable author statement protein processing ; GO:0016485 | non-traceable author statement endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR030225 Golgi membrane ; GO:0000139 | inferred from electronic annotation with InterPro:IPR030225 "dSCAP, Scap_Dm, CG8356, CG14592, CG33131, SCAP, Scap, dScap, dscap" "IPR030225:Sterol regulatory element-binding protein cleavage-activating protein, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000731:Sterol-sensing domain, IPR001680:WD40 repeat, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR011042:Six-bladed beta-propeller, TolB-like" CG33131 11-Aug-17 DroID_v2017_08 "Drer\npc1, Drer\scap, Drer\npc1l1" Scer\NCR1 Cele\scp-1 "Xtro\npc1l1, Xtro\npc1, Xtro\scap" "Mmus\Scap, Mmus\Npc1, Mmus\Npc1l1" "Hsap\NPC1L1, Hsap\NPC1, Hsap\SCAP" "viable,reduced,developmental rate defective" FBgn0046253 CG3502 - http://flybase.org/reports/FBgn0046253 protein_coding_gene peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "BEST:LD34564, CG3502" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG3502 11-Aug-17 DroID_v2017_08 "Drer\npepps, Drer\erap2, Drer\si:ch211-106j24.1, Drer\si:ch211-276a23.5, Drer\si:ch211-149p5.1, Drer\erap1b, Drer\lnpep, Drer\anpepb, Drer\anpepa, Drer\si:ch211-198g19.1, Drer\erap1a, Drer\enpep" "Scer\AAP1, Scer\TMA108, Scer\APE2" "Cele\T12E12.6, Cele\R03G8.6, Cele\T07F10.1, Cele\Y67D8C.9, Cele\mnp-1, Cele\T16G12.1, Cele\F49B2.6, Cele\pam-1, Cele\VB0395L.1, Cele\R03G8.4, Cele\Y42A5A.1, Cele\AC3.5, Cele\Y53F4B.20" "Xtro\anpep, Xtro\lnpep, Xtro\lvrn, Xtro\npepps, Xtro\enpep, Xtro\erap1" "Mmus\Lnpep, Mmus\Enpep, Mmus\Lvrn, Mmus\Erap1, Mmus\Trhde, Mmus\Anpep, Mmus\Npepps" "Hsap\NPEPPS, Hsap\ANPEP, Hsap\ENPEP, Hsap\ERAP1, Hsap\TRHDE, Hsap\LVRN, Hsap\ERAP2, Hsap\LNPEP" viable FBgn0266365 CR45013 - http://flybase.org/reports/FBgn0266365 non_protein_coding_gene - - - CR45013 - CR45013 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266364 CG45012 - http://flybase.org/reports/FBgn0266364 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN001848130 negative regulation of serine-type endopeptidase activity ; GO:1900004 | inferred from biological aspect of ancestor with PANTHER:PTN001848130 cellular_component ; GO:0005575 | no biological data available CG45012 IPR002350:Kazal domain CG45012 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-203a12.2, Drer\si:dkey-77g12.4, Drer\si:dkey-77g12.1, Drer\si:dkey-203a12.4, Drer\si:dkey-203a12.6, Drer\si:dkey-203a12.8, Drer\si:dkey-203a12.3, Drer\zgc:158852" - - - "Mmus\Spink13, Mmus\Spink14, Mmus\Spink10, Mmus\Spink8, Mmus\Gm10267, Mmus\Spink2, Mmus\Spinkl, Mmus\Spink7, Mmus\Spink11, Mmus\Spink1" "Hsap\SPINK7, Hsap\SPINK8, Hsap\SPINK2, Hsap\SPINK13, Hsap\SPINK14, Hsap\SPINK1, Hsap\SPINK9" FBgn0031786 CG13989 - http://flybase.org/reports/FBgn0031786 protein_coding_gene - - - "BcDNA:AT09383, CG13989" - CG13989 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052118 CG32118 - http://flybase.org/reports/FBgn0052118 protein_coding_gene - - - CG32118 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005034 er erupt http://flybase.org/reports/FBgn0005034 - gene - - - er - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye-antennal disc,eye,ommatidium" FBgn0020355 anon-2G10 anon-2G10 http://flybase.org/reports/FBgn0020355 - gene - - - "2G10, anon-2G10" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261608 RpL37A Ribosomal protein L37A http://flybase.org/reports/FBgn0261608 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR002674, InterPro:IPR011331 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002674, InterPro:IPR011331, InterPro:IPR011332 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR002674, InterPro:IPR011331 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "CG5827, RpL37A, M(2)25C, L37A, RpL37a, DmL37a, BcDNA:RH41593, BcDNA:RE23595, M(2)S1, l(2)25Cb, chr2L:5071724..5071820" "IPR002674:Ribosomal protein L37ae, IPR011331:Ribosomal protein L37ae/L37e, IPR011332:Zinc-binding ribosomal protein" CG5827 11-Aug-17 DroID_v2017_08 Drer\zgc:171772 "Scer\RPL43A, Scer\RPL43B" Cele\rpl-43 Xtro\rpl37a Mmus\Rpl37a Hsap\RPL37A adult stage DRSC02899 IEK -2.225551478 -1.85433955 -1.508742041 -2.806904876 -0.293015328 2.057932251 FBgn0038474 mRpS11 mitochondrial ribosomal protein S11 http://flybase.org/reports/FBgn0038474 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement mRNA 5'-UTR binding ; GO:0048027 | inferred from biological aspect of ancestor with PANTHER:PTN000204884 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82912 small ribosomal subunit rRNA binding ; GO:0070181 | inferred from biological aspect of ancestor with PANTHER:PTN000204884 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82911 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000204884 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:P82911 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82912 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000204884" mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82911 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82912 "MRP-S11, CG5184, BcDNA:RH70248, mRpS11, GH1" IPR001971:Ribosomal protein S11 CG5184 11-Aug-17 DroID_v2017_08 "Drer\rps14, Drer\mrps11" "Scer\MRPS18, Scer\RPS14B, Scer\RPS14A" "Cele\rps-14, Cele\mrps-11" Xtro\mrps11 "Mmus\Rps14, Mmus\Mrps11" "Hsap\MRPS11, Hsap\RPS14" FBgn0264575 Egfr::Hsap\EGFR - http://flybase.org/reports/FBgn0264575 engineered_fusion_gene - - - Egfr::Hsap\EGFR - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051321 CG31321 - http://flybase.org/reports/FBgn0051321 protein_coding_gene molecular_function ; GO:0003674 | no biological data available transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 cellular_component ; GO:0005575 | no biological data available "BcDNA:RH31685, CG31321" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG31321 11-Aug-17 DroID_v2017_08 "Drer\slc46a1, Drer\si:ch211-262i1.4, Drer\hiat1b, Drer\slc46a3, Drer\LOC100002406, Drer\si:dkey-5g14.1, Drer\LOC557306, Drer\zgc:174356, Drer\hiat1a" Scer\YJL163C "Cele\F40F9.5, Cele\Y4C6B.5, Cele\Y43F8A.5" "Xtro\slc46a1, Xtro\mfsd14a, Xtro\slc46a2, Xtro\mfsd14b" "Mmus\Slc46a1, Mmus\Slc46a3, Mmus\Mfsd14a, Mmus\Slc46a2, Mmus\Mfsd14b" "Hsap\MFSD14A, Hsap\SLC46A3, Hsap\SLC46A1, Hsap\MFSD14B, Hsap\SLC46A2" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0039838 CG3669 - http://flybase.org/reports/FBgn0039838 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from electronic annotation with InterPro:IPR018338 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR018338 - CG3669 "IPR001148:Alpha carbonic anhydrase, IPR018338:Carbonic anhydrase, alpha-class, conserved site, IPR023561:Carbonic anhydrase, alpha-class" CG3669 11-Aug-17 DroID_v2017_08 "Drer\ca12, Drer\zgc:153760, Drer\car15, Drer\ca7, Drer\si:ch211-173d10.4, Drer\ca15b, Drer\ca10a, Drer\ptprga, Drer\ca9, Drer\ca6, Drer\ca15c, Drer\ca10b, Drer\ca2, Drer\ca4a, Drer\ca8, Drer\ca4c, Drer\ca5a, Drer\ca16b, Drer\ca14, Drer\ca15a, Drer\cahz, Drer\ca4b" - "Cele\cah-6, Cele\cah-5, Cele\cah-3, Cele\cah-4" "Xtro\LOC779564, Xtro\ca14, Xtro\ca8, Xtro\ca2, Xtro\ca7, Xtro\ca4, Xtro\ca1, Xtro\ca5b, Xtro\ca6, Xtro\ca3, Xtro\ca11, Xtro\ca10, Xtro\ca12" "Mmus\Car5b, Mmus\Car1, Mmus\Car15, Mmus\Car3, Mmus\Car6, Mmus\Car7, Mmus\Car2, Mmus\Car10, Mmus\Car14, Mmus\Car13, Mmus\Car9, Mmus\Car11, Mmus\Car12, Mmus\Car8, Mmus\Car4, Mmus\Ptprg, Mmus\Car5a" "Hsap\CA4, Hsap\CA5A, Hsap\CA1, Hsap\CA9, Hsap\CA12, Hsap\CA11, Hsap\CA3, Hsap\CA13, Hsap\CA5B, Hsap\CA14, Hsap\CA2, Hsap\CA8, Hsap\CA10, Hsap\CA7, Hsap\CA6, Hsap\PTPRG" FBgn0267459 CR45809 - http://flybase.org/reports/FBgn0267459 non_protein_coding_gene - - - CR45809 - CR45809 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260012 pds5 precocious dissociation of sisters 5 http://flybase.org/reports/FBgn0260012 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern karyosome formation ; GO:0030717 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype mitotic sister chromatid cohesion ; GO:0007064 | inferred from biological aspect of ancestor with PANTHER:PTN000292173 mitotic cohesin unloading ; GO:0061781 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000292173 chromatin ; GO:0000785 | inferred from biological aspect of ancestor with PANTHER:PTN000292173 polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Pds5, dPds5, CG17509, l(2)k13312, anon-WO0118547.183, pds5, PDS5" "IPR016024:Armadillo-type fold, IPR013763:Cyclin-like, IPR011989:Armadillo-like helical" CG17509 11-Aug-17 DroID_v2017_08 "Drer\pds5a, Drer\pds5b" Scer\PDS5 Cele\evl-14 "Xtro\pds5a, Xtro\pds5b" "Mmus\Pds5b, Mmus\Pds5a" "Hsap\PDS5B, Hsap\PDS5A" FBgn0065418 l(2)SH1531 lethal (2) SH1531 http://flybase.org/reports/FBgn0065418 gene - - - "l(2)SH1531, l(2)SH2 1531" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261885 osa osa http://flybase.org/reports/FBgn0261885 protein_coding_gene transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 DNA binding ; GO:0003677 | non-traceable author statement DNA binding ; GO:0003677 | inferred from direct assay "chromatin remodeling ; GO:0006338 | inferred from electronic annotation with InterPro:IPR021906 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from physical interaction with ham segment specification ; GO:0007379 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap neuroblast fate commitment ; GO:0014017 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from genetic interaction with numb inferred from genetic interaction with brat regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay brahma complex ; GO:0035060 | traceable author statement brahma complex ; GO:0035060 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "OSA, eyelid, osa, Osa, CG7467, eld, en(lz)4F/4H, p300, E(E2F)3C, l(3)04539, l(3)00090, l(3)j9C3, anon-WO0172774.126, anon-WO0118547.314, C819" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR001606:ARID DNA-binding domain, IPR021906:SWI/SNF-like complex subunit BAF250/Osa, IPR033388:SWI/SNF-like complex subunit BAF250, C-terminal" CG7467 11-Aug-17 DroID_v2017_08 "Drer\arid1ab, Drer\arid1aa, Drer\arid5b, Drer\arid3b, Drer\arid1b, Drer\arid3a, Drer\arid3c, Drer\arid4a" "Scer\RSC9, Scer\SWI1, Scer\ECM5" "Cele\arid-1, Cele\cfi-1, Cele\let-526" "Xtro\arid1b, Xtro\arid3b, Xtro\arid3a, Xtro\arid1a" "Mmus\Arid3a, Mmus\Arid3c, Mmus\Arid4a, Mmus\Arid4b, Mmus\Arid5b, Mmus\Arid1b, Mmus\Arid3b, Mmus\Arid5a, Mmus\Arid1a" "Hsap\ARID3C, Hsap\ARID3A, Hsap\ARID1A, Hsap\ARID4A, Hsap\ARID4B, Hsap\ARID5B, Hsap\ARID1B, Hsap\ARID5A, Hsap\ARID3B" " larval stage , embryonic stage | early " " larval salivary gland

,

ubiquitous , morphogenetic furrow | anterior to

, eye disc

, dorsal mesothoracic disc

" DRSC03744 IE -0.083839134 -3.507738129 -0.47039841 1.688272232 FBgn0029809 CG15767 - http://flybase.org/reports/FBgn0029809 protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 - CG15767 "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain" CG15767 11-Aug-17 DroID_v2017_08 "Drer\ppifb, Drer\ppid, Drer\ppiaa, Drer\ppifa, Drer\ppiab" "Scer\CPR3, Scer\CPR1" Cele\T22F3.12 "Xtro\ppia, Xtro\ppif" "Mmus\Ranbp2, Mmus\Ppia, Mmus\Ppid, Mmus\Ppif" "Hsap\PPIAL4E, Hsap\PPID, Hsap\PPIA, Hsap\PPIF, Hsap\RANBP2, Hsap\PPIAL4A, Hsap\LOC105371242, Hsap\PPIAL4D, Hsap\PPIAL4G, Hsap\PPIAL4C" viable DRSC29131 K 0.028478082 0.478489976 0.458077061 0.504459433 -1.94110309 0.176577654 FBgn0005022 dkl darker legs http://flybase.org/reports/FBgn0005022 - gene - - - "thl[d], thl-d, dkl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile,poor,visible,reduced,body color defective" "eye,wing,leg,adult thorax,adult abdomen" FBgn0069219 gl(3R)53-6 gl(3R)53-6 http://flybase.org/reports/FBgn0069219 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(3R)53-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,recessive,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment,embryonic abdominal segment" FBgn0032150 CG13123 - http://flybase.org/reports/FBgn0032150 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG13123 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG13123 11-Aug-17 DroID_v2017_08 Drer\si:dkey-208k4.2 Scer\PZF1 Cele\ZK546.5 - - "Hsap\ZNF112, Hsap\ZBTB24" viable DRSC02219 IE 0.321201511 -1.692175389 -1.716207126 -0.003728123 -0.982427981 0.131021487 FBgn0021808 l(2)k16703 lethal (2) k16703 http://flybase.org/reports/FBgn0021808 - gene - - - l(2)k16703 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065462 l(2)SH1362 lethal (2) SH1362 http://flybase.org/reports/FBgn0065462 gene - - - "l(2)SH1362, l(2)SH2 1362" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266123 T:PACT-Plp PACT domain of Plp http://flybase.org/reports/FBgn0266123 engineered_tag - - - "T:PACT-Plp, T:PACT-cp309" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060541 l(3)S099908 lethal (3) S099908 http://flybase.org/reports/FBgn0060541 gene - - - "0999/08, l(3)S099908" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265469 CG44362 - http://flybase.org/reports/FBgn0265469 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44362 - CG44362 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260468 CG7950 - http://flybase.org/reports/FBgn0260468 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7950, Dromel_CG7950_FBtr0085563_CHCHD4inmorf_mORF" IPR010625:CHCH CG7950 11-Aug-17 DroID_v2017_08 "Drer\chchd4b, Drer\chchd4a" Scer\MIA40 "Cele\ZK616.3, Cele\F42H10.2, Cele\F11C1.1, Cele\ZK616.2" Xtro\chchd4 Mmus\Chchd4 Hsap\CHCHD4 DRSC28664 IK 2.175635786 0.510433806 0.616536938 -0.532649585 2.144138521 0.143507261 FBgn0010854 l(3)05057 lethal (3) 05057 http://flybase.org/reports/FBgn0010854 - gene - - - l(3)05057 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0065494 l(2)SH1225 lethal (2) SH1225 http://flybase.org/reports/FBgn0065494 gene - - - "l(2)SH1225, l(2)SH2 1225" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069117 mus213 mutagen-sensitive 213 http://flybase.org/reports/FBgn0069117 gene - - - mus213 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0066073 Su(var)2-13 Su(var)2-13 http://flybase.org/reports/FBgn0066073 gene - - - Su(var)2-13 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264355 4A1 - http://flybase.org/reports/FBgn0264355 gene - - - 4A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "eye,somatic clone" FBgn0002530 Lap-D Leucine aminopeptidase D http://flybase.org/reports/FBgn0002530 "FBgn0013289, FBgn0013290" gene aminopeptidase activity ; GO:0004177 | inferred from direct assay - cytosol ; GO:0005829 | inferred from direct assay "LAP, Lap, LAP-D, LapD, Lap-D" - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0036771 CG14353 - http://flybase.org/reports/FBgn0036771 protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from sequence or structural similarity with HGNC:9317 calcineurin-NFAT signaling cascade ; GO:0033173 | inferred from sequence or structural similarity with HGNC:9317 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with HGNC:9317 calcineurin complex ; GO:0005955 | inferred from sequence or structural similarity with HGNC:9317 CG14353 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG14353 11-Aug-17 DroID_v2017_08 "Drer\ppp3r1b, Drer\wdr92" - "Cele\cnb-1, Cele\Y54H5A.1" "Xtro\ppp3r1, Xtro\wdr92" "Mmus\Ppp3r1, Mmus\Ppp3r2, Mmus\Wdr92" "Hsap\PPP3R1, Hsap\WDR92, Hsap\PPP3R2" viable FBgn0026787 Nhe1 Na[+]/H[+] hydrogen exchanger 1 http://flybase.org/reports/FBgn0026787 - protein_coding_gene potassium:proton antiporter activity ; GO:0015386 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 sodium:proton antiporter activity ; GO:0015385 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 "sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR004709, InterPro:IPR018409 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 potassium ion transmembrane transport ; GO:0071805 | inferred from biological aspect of ancestor with PANTHER:PTN000011605" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004709, InterPro:IPR006153, InterPro:IPR018409, InterPro:IPR018422 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000011723" "DmNHE1, NHE1, CG12178, Nhe1, nhe1" "IPR018409:Na+/H+ exchanger, isoform 8, IPR018422:Cation/H+ exchanger, CPA1 family, IPR004709:Na+/H+ exchanger, IPR006153:Cation/H+ exchanger" CG12178 11-Aug-17 DroID_v2017_08 "Drer\slc9a6a, Drer\slc9a8, Drer\slc9a6b" Scer\NHX1 Cele\nhx-8 "Xtro\slc9a9, Xtro\slc9a7, Xtro\slc9a6, Xtro\slc9a8" "Mmus\Slc9a6, Mmus\Slc9c1, Mmus\Slc9a9, Mmus\Slc9a7, Mmus\Slc9a8" "Hsap\SLC9A6, Hsap\SLC9A9, Hsap\SLC9C1, Hsap\SLC9A8, Hsap\SLC9A7" viable FBgn0010373 sib sibless http://flybase.org/reports/FBgn0010373 - gene - - - sib - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259718 CG42372 - http://flybase.org/reports/FBgn0259718 protein_coding_gene - - - "CG42372, Dromel_CG30100_FBtr0087140_uORF" IPR008011:Complex 1 LYR protein CG42372 11-Aug-17 DroID_v2017_08 Drer\sdhaf1 Scer\SDH6 - - Mmus\Sdhaf1 Hsap\SDHAF1 FBgn0010936 l(3)09656 lethal (3) 09656 http://flybase.org/reports/FBgn0010936 - gene - - - l(3)09656 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0061135 l(3)S001620b lethal (3) S001620b http://flybase.org/reports/FBgn0061135 gene - - - "0016/20, l(3)S001620b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065460 l(2)SH1380 lethal (2) SH1380 http://flybase.org/reports/FBgn0065460 gene - - - "l(2)SH1380, l(2)SH2 1380" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267381 T:CycB.1-266 CycB degron sequence http://flybase.org/reports/FBgn0267381 engineered_tag - - - T:CycB.1-266 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060909 l(3)S043005a lethal (3) S043005a http://flybase.org/reports/FBgn0060909 gene - - - "0430/05, l(3)S043005a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0243486 rdo reduced ocelli http://flybase.org/reports/FBgn0243486 protein_coding_gene - ocellus development ; GO:0008056 | inferred from mutant phenotype - "rdo, PFE, CG15151, CT35050, Rdo" "IPR003591:Leucine-rich repeat, typical subtype, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG15151 11-Aug-17 DroID_v2017_08 "Drer\ppp1r42, Drer\si:dkey-182i3.11" Scer\CYR1 Cele\dma-1 - Mmus\Ppp1r42 Hsap\PPP1R42 FBgn0060403 l(3)S131103 lethal (3) S131103 http://flybase.org/reports/FBgn0060403 gene - - - "1311/03, l(3)S131103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031824 CG9547 - http://flybase.org/reports/FBgn0031824 protein_coding_gene flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786 glutaryl-CoA dehydrogenase activity ; GO:0004361 | inferred from sequence or structural similarity with UniProtKB:Q92947 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006091, InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786 tryptophan metabolic process ; GO:0006568 | inferred from sequence or structural similarity with UniProtKB:Q92947 lysine catabolic process ; GO:0006554 | inferred from sequence or structural similarity with UniProtKB:Q92947 hydroxylysine catabolic process ; GO:0046948 | inferred from sequence or structural similarity with UniProtKB:Q92947" microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q92947 "152078_at, CG9547" "IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal" CG9547 11-Aug-17 DroID_v2017_08 "Drer\gcdha, Drer\gcdhb" - "Cele\F54D5.7, Cele\acdh-10" Xtro\gcdh Mmus\Gcdh Hsap\GCDH DRSC03260 K -0.49002739 -0.396702213 0.227175872 0.211034442 2.069404073 0.002644414 FBgn0014068 Su(tor)3-344 Su(tor)3-344 http://flybase.org/reports/FBgn0014068 - gene - - - Su(tor)3-344 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014885 Su(phl)4 Suppressor of pole hole 4 http://flybase.org/reports/FBgn0014885 - gene - - - "Su(D-raf)4, Su(phl)4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026218 l(3)06265 lethal (3) 06265 http://flybase.org/reports/FBgn0026218 - gene - - - l(3)06265 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029801 CG15771 - http://flybase.org/reports/FBgn0029801 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR006439, InterPro:IPR011950" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 - "CR33074, CG15771, 28571108" "IPR006439:HAD hydrolase, subfamily IA, IPR011950:HAD-superfamily hydrolase, subfamily IA, CTE7, IPR023214:HAD-like domain" CG15771 11-Aug-17 DroID_v2017_08 "Drer\hdhd3, Drer\nanp, Drer\ephx2" "Scer\YOR131C, Scer\YMR130W" "Cele\K01G5.10, Cele\F09C3.2, Cele\K09H11.1, Cele\C04E6.7" "Xtro\acad10, Xtro\ephx2, Xtro\hdhd3, Xtro\nanp" "Mmus\Nanp, Mmus\Hdhd3, Mmus\Ephx2, Mmus\Acad10" "Hsap\ACAD10, Hsap\EPHX2, Hsap\HDHD3, Hsap\NANP" viable embryonic/larval hemocyte | third instar larval stage FBgn0041153 freshair freshair http://flybase.org/reports/FBgn0041153 gene - - - freshair - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082922 snoRNA:Or-aca4 snoRNA:Or-aca4 http://flybase.org/reports/FBgn0082922 snoRNA_gene - - - "snoRNA:Or-aca4, DmOr_aca4 snoRNA, DmOr_aca4, CR34543, Or-aca4, Oaca-4, chr2R:13131609..13131698, snoRNA:Or-ACA4" - CR34543 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030048 CG12112 - http://flybase.org/reports/FBgn0030048 protein_coding_gene - - - CG12112 IPR032071:Domain of unknown function DUF4806 CG12112 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0014213 l(2)31Ba lethal (2) 31Ba http://flybase.org/reports/FBgn0014213 - gene - - - l(2)31Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085192 CG34163 - http://flybase.org/reports/FBgn0085192 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34163 - CG34163 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002282 l(3)73Ag lethal (3) 73Ag http://flybase.org/reports/FBgn0002282 - gene - - - "l(3)133.59, l(3)73Ag" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "adult abdomen,tergite" FBgn0002288 l(3)73Ca lethal (3) 73Ca http://flybase.org/reports/FBgn0002288 - gene - - - l(3)73Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031596 CG15429 - http://flybase.org/reports/FBgn0031596 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "BcDNA:AT23465, CG15429" IPR001199:Cytochrome b5-like heme/steroid binding domain CG15429 11-Aug-17 DroID_v2017_08 Drer\cyb5d1 - - Xtro\cyb5d1 Mmus\Cyb5d1 Hsap\CYB5D1 "viable,visible" chaeta FBgn0028564 slug slug http://flybase.org/reports/FBgn0028564 gene - - - slug - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" larva FBgn0019749 l(1)815-5 lethal (1) 815-5 http://flybase.org/reports/FBgn0019749 - gene - - - l(1)815-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015356 anon-99Ce anon-99Ce http://flybase.org/reports/FBgn0015356 - gene - - - anon-99Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019908 air aircraft http://flybase.org/reports/FBgn0019908 - gene - - - air - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,flightless" wing FBgn0069956 CG41063 - http://flybase.org/reports/FBgn0069956 protein_coding_gene - - - CG41063 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032299 CG17127 - http://flybase.org/reports/FBgn0032299 protein_coding_gene - - - CG17127 - CG17127 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034301 CG5756 - http://flybase.org/reports/FBgn0034301 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG5756 IPR002557:Chitin binding domain CG5756 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - "viable,visible" mesothoracic tergum FBgn0266914 CR45374 - http://flybase.org/reports/FBgn0266914 non_protein_coding_gene - - - CR45374 - CR45374 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014331 l(3)ry87 lethal (3) ry87 http://flybase.org/reports/FBgn0014331 - gene - - - l(3)ry87 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034272 Ir54a Ionotropic receptor 54a http://flybase.org/reports/FBgn0034272 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir54a, DmelIR54a, CG14487, IR54a" - CG14487 11-Aug-17 DroID_v2017_08 "Drer\grik4, Drer\grik1a, Drer\grik1b, Drer\si:dkey-183j2.10, Drer\si:ch211-251b21.1" - "Cele\glr-4, Cele\glr-5" - "Mmus\Grik1, Mmus\Grik4" "Hsap\GRIK1, Hsap\GRIK4" viable DRSC06459 K 0.152835364 -0.162004685 0.301238081 0.461127447 1.500600904 0.769335715 FBgn0010636 l(2)07129 lethal (2) 07129 http://flybase.org/reports/FBgn0010636 - gene - - - l(2)07129 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0037454 CG1137 - http://flybase.org/reports/FBgn0037454 protein_coding_gene - - - "anon-WO0118547.86, CG1137" "IPR000048:IQ motif, EF-hand binding site" CG1137 11-Aug-17 DroID_v2017_08 Drer\iqcd - - Xtro\iqcd Mmus\Iqcd Hsap\IQCD viable FBgn0260617 2L1748 - http://flybase.org/reports/FBgn0260617 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1748 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0000971 Fs(2)Him Female sterile (2) Himca http://flybase.org/reports/FBgn0000971 - gene - - - "Himca, Fs(2)Sz5, Fs(2)Him" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,dominant" egg FBgn0044056 Gpal Gpal http://flybase.org/reports/FBgn0044056 gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "GPAL, Gpal" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015034 Cyp4e1 Cytochrome P450-4e1 http://flybase.org/reports/FBgn0015034 FBgn0033293 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4e1, CYP4E1, P450, P-450, CG2062, Cyp4e1, CYP4e1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG2062 11-Aug-17 DroID_v2017_08 "Drer\cyp46a1.1, Drer\cyp3c4, Drer\cyp20a1, Drer\cyp26c1, Drer\cyp46a1.4, Drer\cyp26b1, Drer\cyp4v8, Drer\cyp4f3, Drer\cyp3a65, Drer\cyp19a1a, Drer\cyp26a1, Drer\cyp3c2, Drer\cyp3c1, Drer\cyp4v7, Drer\cyp46a1.3, Drer\cyp46a1.2, Drer\LOC100329425, Drer\cyp4t8, Drer\cyp3c3, Drer\cyp19a1b" "Scer\ERG5, Scer\DIT2" "Cele\cyp-29A4, Cele\cyp-25A4, Cele\cyp-29A2, Cele\cyp-13A7, Cele\cyp-37A1, Cele\cyp-13A1, Cele\cyp-13A5, Cele\cyp-13A12, Cele\cyp-25A3, Cele\cyp-13A3, Cele\cyp-13A11, Cele\cyp-13A8, Cele\cyp-31A2, Cele\cyp-13A10, Cele\cyp-37B1, Cele\cyp-31A5, Cele\cyp-32B1, Cele\cyp-29A3, Cele\cyp-25A1, Cele\cyp-42A1, Cele\cyp-31A3, Cele\cyp-25A2, Cele\cyp-13A4, Cele\cyp-32A1" "Xtro\cyp20a1, Xtro\cyp4v2, Xtro\cyp26c1, Xtro\cyp26a1, Xtro\cyp4b1, Xtro\cyp4b1.2, Xtro\mgc108213, Xtro\cyp4f2, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\cyp19a1, Xtro\cyp26b1, Xtro\LOC100487918" "Mmus\Cyp3a41b, Mmus\Cyp4b1, Mmus\Cyp26a1, Mmus\Cyp4a30b, Mmus\Cyp4f15, Mmus\Cyp19a1, Mmus\Cyp4f14, Mmus\Cyp3a16, Mmus\Cyp4a14, Mmus\Cyp4f13, Mmus\Cyp4f17, Mmus\Cyp3a41a, Mmus\Cyp4a29, Mmus\Cyp4a12b, Mmus\Cyp4f39, Mmus\Cyp3a59, Mmus\Cyp4f16, Mmus\Cyp3a25, Mmus\Cyp26b1, Mmus\Cyp3a11, Mmus\Cyp26c1, Mmus\Cyp4f18, Mmus\Cyp3a57, Mmus\Cyp46a1, Mmus\Cyp20a1, Mmus\Cyp4v3, Mmus\Cyp3a44, Mmus\Cyp4a32, Mmus\Cyp3a13, Mmus\Cyp4a12a, Mmus\Cyp4f37, Mmus\Cyp4f40, Mmus\Cyp4x1, Mmus\Cyp4a10, Mmus\Cyp4a31" "Hsap\CYP20A1, Hsap\CYP4A22, Hsap\CYP46A1, Hsap\CYP4F22, Hsap\CYP4F12, Hsap\CYP4B1, Hsap\CYP3A43, Hsap\CYP3A7, Hsap\CYP26A1, Hsap\CYP4F11, Hsap\CYP19A1, Hsap\CYP4A11, Hsap\CYP3A4, Hsap\CYP4V2, Hsap\CYP4F3, Hsap\CYP3A5, Hsap\CYP4X1, Hsap\CYP4F2, Hsap\CYP26B1, Hsap\CYP4Z1, Hsap\CYP4F8, Hsap\CYP26C1" viable FBgn0004590 Eig71Ec Ecdysone-induced gene 71Ec http://flybase.org/reports/FBgn0004590 - protein_coding_gene - metamorphosis ; GO:0007552 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 extracellular region ; GO:0005576 | inferred from sequence model "L71-3, L71, III, gene III, gene-III, CG7608, Eig71Ec, LP11175p, Eig 71Ec" IPR003475:Insect protein of unknown function CG7608 11-Aug-17 DroID_v2017_08 - - Cele\W08F4.10 - - - viable FBgn0065796 l(2)SH0416 lethal (2) SH0416 http://flybase.org/reports/FBgn0065796 gene - - - l(2)SH0416 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029690 CG6414 - http://flybase.org/reports/FBgn0029690 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 - - CG6414 "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG6414 11-Aug-17 DroID_v2017_08 "Drer\nlgn4a, Drer\ces2, Drer\ces3, Drer\nlgn3b, Drer\nlgn2a, Drer\nlgn3a, Drer\si:ch211-93f2.1, Drer\nlgn1, Drer\cel.1, Drer\cell, Drer\nlgn2b, Drer\nlgn4b" - "Cele\K11G9.2, Cele\F15A8.6, Cele\T07H6.1, Cele\E01G6.3, Cele\T22D1.11, Cele\K11G9.1, Cele\C42D4.2, Cele\C17H12.4, Cele\Y71H2AM.13, Cele\C01B10.4, Cele\C01B10.10, Cele\C23H4.2, Cele\R173.3, Cele\C52A10.1, Cele\F07C4.12, Cele\ZC376.1, Cele\ZK994.1, Cele\ZC376.3, Cele\T28C12.5, Cele\T02B5.1, Cele\T28C12.4, Cele\ZC376.2, Cele\F56C11.6, Cele\F13H6.3, Cele\C23H4.4, Cele\ges-1, Cele\C23H4.3, Cele\C23H4.7, Cele\K11G9.3, Cele\T02B5.3" "Xtro\nlgn3, Xtro\nlgn2, Xtro\ces2, Xtro\ces3, Xtro\bche, Xtro\nlgn4x, Xtro\cel, Xtro\LOC100494782" "Mmus\Ces1h, Mmus\Ces1c, Mmus\Ces2b, Mmus\Ces4a, Mmus\Ces1b, Mmus\Ces1e, Mmus\Ces3b, Mmus\Ces5a, Mmus\Ces1f, Mmus\Ces2g, Mmus\Ces2f, Mmus\Ces1g, Mmus\Nlgn1, Mmus\Ces2a, Mmus\Cel, Mmus\Ces3a, Mmus\Ces1d, Mmus\Nlgn2, Mmus\Ces1a, Mmus\Ces2e, Mmus\Ces2c, Mmus\Nlgn3, Mmus\Ces2h" "Hsap\CES2, Hsap\CES3, Hsap\NLGN1, Hsap\CES5A, Hsap\CES4A, Hsap\NLGN4Y, Hsap\NLGN2, Hsap\NLGN3, Hsap\CES1, Hsap\NLGN4X, Hsap\CEL" viable FBgn0065696 l(2)SH0636 lethal (2) SH0636 http://flybase.org/reports/FBgn0065696 gene - - - "l(2)SH0636, l(2)SH2 0636" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001401 l(1)2Fd lethal (1) 2Fd http://flybase.org/reports/FBgn0001401 - gene - - - "l26, D82, l(1)EC226, N11, EC226, N6, l(1)N8, l(1)N11, l(1)2Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0265797 CR44586 - http://flybase.org/reports/FBgn0265797 non_protein_coding_gene - - - CR44586 - CR44586 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260086 2L3910 - http://flybase.org/reports/FBgn0260086 gene - - - 2L3910 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0261004 asl asterless http://flybase.org/reports/FBgn0261004 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sas-4 negative regulation of centriole elongation ; GO:1903723 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype single fertilization ; GO:0007338 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from direct assay centrosome cycle ; GO:0007098 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype pericentriolar material ; GO:0000242 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay centriole ; GO:0005814 | colocalizes_with inferred from direct assay ciliary basal body ; GO:0036064 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "Asl, ASL, asl, CG2919, sdu, mecD" - CG2919 11-Aug-17 DroID_v2017_08 - Scer\SLK19 Cele\F18H3.4 - - - FBgn0026156 wlf wolf http://flybase.org/reports/FBgn0026156 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available wlf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022399 Gase3 Gastric serine protease 3 http://flybase.org/reports/FBgn0022399 - gene - - - Gase3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067634 233y-a 233y-a http://flybase.org/reports/FBgn0067634 gene - - - "233y, 233y-a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0264261 CR43761 - http://flybase.org/reports/FBgn0264261 non_protein_coding_gene - - - "CR43761, lincRNA.155" - CR43761 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263892 l(3)GL45 - http://flybase.org/reports/FBgn0263892 gene - - - l(3)GL45 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0061140 l(3)S000625b lethal (3) S000625b http://flybase.org/reports/FBgn0061140 gene - - - "0006/25, l(3)S000625b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262376 mir-219 mir-219 stem loop http://flybase.org/reports/FBgn0262376 miRNA_gene - - - "dme-mir-219, mir-219, MIR-219, CR42897, miR-219, CR33579" - CR42897 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,lethal - all die before end of first instar larval stage,some die during first instar larval stage" "eye,wing,1st posterior cell" FBgn0034563 CG15649 - http://flybase.org/reports/FBgn0034563 protein_coding_gene - - - "CG15649, BcDNA:GH08880" - CG15649 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective,planar polarity defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0036134 FoxK Forkhead box K http://flybase.org/reports/FBgn0036134 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456 cellular response to virus ; GO:0098586 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype visceral mesoderm-endoderm interaction involved in midgut development ; GO:0007495 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "CG11799, MNF, DmLD16137, DmMNF, FoxK, fork head transcription factor short isoform, fork head transcription factor long isoform, Mnf, dFoxK, fd68A" "IPR018122:Fork head domain conserved site1, IPR000253:Forkhead-associated (FHA) domain, IPR001766:Fork head domain, IPR008984:SMAD/FHA domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR030456:Fork head domain conserved site 2" CG11799 11-Aug-17 DroID_v2017_08 "Drer\foxl1, Drer\foxf2a, Drer\si:ch211-262e15.1, Drer\foxi2, Drer\zgc:113424, Drer\foxq1b, Drer\foxb2, Drer\foxk1, Drer\foxb1b, Drer\foxq2, Drer\si:rp71-45k5.2, Drer\foxk2, Drer\foxb1a, Drer\foxd2, Drer\foxj1a, Drer\foxd3, Drer\foxg1a" "Scer\HCM1, Scer\FKH2, Scer\FHL1, Scer\FKH1" "Cele\lin-31, Cele\pha-4, Cele\fkh-2, Cele\fkh-10, Cele\unc-130" "Xtro\foxd3, Xtro\foxi4.2, Xtro\foxb1, Xtro\foxd4l1.1, Xtro\foxj1.2, Xtro\foxj1, Xtro\foxd2, Xtro\foxq1, Xtro\foxh1, Xtro\foxk2" "Mmus\Foxj1, Mmus\Foxk1, Mmus\Foxg1, Mmus\Foxm1, Mmus\Foxb2, Mmus\Foxb1, Mmus\Foxk2, Mmus\Foxl1, Mmus\Foxq1, Mmus\Foxd3" "Hsap\FOXQ1, Hsap\AP5Z1, Hsap\FOXB1, Hsap\FOXG1, Hsap\FOXJ1, Hsap\FOXK1, Hsap\FOXD3, Hsap\FOXB2, Hsap\FOXK2, Hsap\FOXD4, Hsap\FOXL1" viable FBgn0033683 CG18343 - http://flybase.org/reports/FBgn0033683 protein_coding_gene - - - CG18343 - CG18343 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051619 nolo no long nerve cord http://flybase.org/reports/FBgn0051619 protein_coding_gene metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR013273 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR013273 ventral cord development ; GO:0007419 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR013273 "CG31619, CG2131, CT6940, CG2122, CG13236, nolo" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR010909:PLAC, IPR013273:Peptidase M12B, ADAM-TS, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003599:Immunoglobulin subtype" CG31619 11-Aug-17 DroID_v2017_08 "Drer\LOC100002059, Drer\adamtsl2, Drer\adamts18, Drer\adamts8a, Drer\adamts2, Drer\adamtsl5, Drer\adamts6, Drer\adamts7, Drer\LOC568792, Drer\adamts15a, Drer\adamts1, Drer\adamts12, Drer\adamts13, Drer\adamtsl3, Drer\thsd7bb" - Cele\madd-4 "Xtro\thsd7b, Xtro\adamts20, Xtro\adamts6, Xtro\adamtsl3, Xtro\adamts9, Xtro\adamts7, Xtro\adamts15, Xtro\adamts16, Xtro\adamts18, Xtro\adamts12" "Mmus\Adamts6, Mmus\Adamts14, Mmus\Adamts12, Mmus\Adamtsl1, Mmus\Thsd7a, Mmus\Adamts4, Mmus\Adamts13, Mmus\Adamtsl3, Mmus\Adamts20, Mmus\Adamts10, Mmus\Adamts8, Mmus\Sspo, Mmus\Adamts7, Mmus\Adamts19, Mmus\Adamts18, Mmus\Thsd4, Mmus\Adamts15, Mmus\Adamtsl5, Mmus\Adamts9, Mmus\Adamts1, Mmus\Adamts16, Mmus\Adamtsl4" "Hsap\ADAMTSL1, Hsap\ADAMTS20, Hsap\ADAMTS15, Hsap\ADAMTS4, Hsap\ADAMTS6, Hsap\THSD4, Hsap\ADAMTS16, Hsap\ADAMTS19, Hsap\ADAMTS1, Hsap\ADAMTSL5, Hsap\ADAMTS14, Hsap\ADAMTS9, Hsap\ADAMTS10, Hsap\ADAMTS7, Hsap\ADAMTS8, Hsap\ADAMTSL4, Hsap\ADAMTS18, Hsap\ADAMTS13, Hsap\ADAMTS12, Hsap\ADAMTS17, Hsap\THSD7B, Hsap\ADAMTSL3" "visible,partially lethal - majority die,some die during pupal stage,lethal" mesothoracic tergum FBgn0267309 CR45745 - http://flybase.org/reports/FBgn0267309 non_protein_coding_gene - - - CR45745 - CR45745 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033997 Ir51a Ionotropic receptor 51a http://flybase.org/reports/FBgn0033997 pseudogene_attribute - - - "CG12953, DmelIR51a, CR12953, Ir51a, IR51a" - CR12953 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035318 CG9018 - http://flybase.org/reports/FBgn0035318 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG9018, FBgn0035318" "IPR006569:CID domain, IPR006903:RNA polymerase II-binding domain, IPR008942:ENTH/VHS, IPR032337:Cell-cycle alteration and expression-elevated protein in tumour" CG9018 11-Aug-17 DroID_v2017_08 "Drer\slc30a8, Drer\rprd2b, Drer\rprd1b, Drer\rprd2a" Scer\RTT103 "Cele\cids-2, Cele\cids-1" "Xtro\rprd2, Xtro\rprd1a, Xtro\rprd1b" "Mmus\Rprd1a, Mmus\Rprd1b, Mmus\Rprd2" "Hsap\RPRD1B, Hsap\RPRD2, Hsap\RPRD1A" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0039015 Takl2 Tak1-like 2 http://flybase.org/reports/FBgn0039015 protein_coding_gene "MAP kinase kinase kinase activity ; GO:0004709 | inferred from electronic annotation with InterPro:IPR017421 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR017421 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN001147562 protein kinase activity ; GO:0004672 | non-traceable author statement signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058" protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 protein phosphorylation ; GO:0006468 | non-traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001147562 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with Tak1 "CG4803, TAK, Takl2, takl2" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017421:Mitogen-activated protein (MAP) kinase kinase kinase 7" CG4803 11-Aug-17 DroID_v2017_08 "Drer\ripk2, Drer\map3k9, Drer\map3k10, Drer\mos, Drer\ripk4, Drer\map3k7, Drer\ripk3, Drer\si:ch211-120p12.3, Drer\ripk1l, Drer\pbk, Drer\LOC405768, Drer\lrrk2, Drer\dstyk, Drer\zak" - "Cele\Y105C5A.24, Cele\mom-4" "Xtro\dstyk, Xtro\lrrk1, Xtro\map3k7, Xtro\zak, Xtro\pbk, Xtro\map3k9, Xtro\mlkl, Xtro\map3k10, Xtro\lrrk2, Xtro\LOC100490493, Xtro\ankk1, Xtro\ripk1, Xtro\ripk4" "Mmus\Map3k7, Mmus\Lrrk1, Mmus\Lrrk2, Mmus\Ripk4, Mmus\Pbk, Mmus\BC021891, Mmus\Dstyk, Mmus\Map3k11, Mmus\Map3k10, Mmus\Map3k9, Mmus\Ripk1, Mmus\Mos, Mmus\Zak, Mmus\Mlkl, Mmus\Ripk3, Mmus\Ripk2" "Hsap\IKBKB, Hsap\LRRK2, Hsap\MAP3K7, Hsap\MOS, Hsap\MLKL, Hsap\RIPK1, Hsap\MAP3K9, Hsap\MAP3K11, Hsap\PBK, Hsap\MAP3K21, Hsap\MAP3K10, Hsap\RIPK4, Hsap\DSTYK, Hsap\LRRK1, Hsap\RIPK2, Hsap\MAP3K20, Hsap\RIPK3" "viable,fertile" DRSC15650 K -0.317109345 0.089296187 -0.159757247 -0.068964564 0.459173196 -1.558132663 FBgn0027985 l(3)S132703 lethal (3) S132703 http://flybase.org/reports/FBgn0027985 gene - - - "1327/03, l(3)S132703" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0004778 Ccp84Af Ccp84Af http://flybase.org/reports/FBgn0004778 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype extracellular matrix ; GO:0031012 | inferred from sequence model "cc3, CG1331, BG:DS00004.6, Ccp84Af, Ccp, DmelCcp84Af" IPR000618:Insect cuticle protein CG1331 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC12591 I -0.79306758 -1.600176981 -1.23938521 0.336325075 0.1576713 0.231526345 FBgn0044125 E(rst)B37 E(rst)B37 http://flybase.org/reports/FBgn0044125 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B37, E(rst)B37" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014988 l(2)46Dd lethal (2) 46Dd http://flybase.org/reports/FBgn0014988 - gene - - - "X, l(2)46Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260243 E(var)3-9 Enhancer of variegation 3-9 http://flybase.org/reports/FBgn0260243 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 chromatin maintenance ; GO:0070827 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "E(var)3-9, CG11971, E-var(3)9, anon1E9, Anon1E9, 1E9, anon-EST:fe1E9" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG11971 11-Aug-17 DroID_v2017_08 "Drer\znf1078, Drer\si:dkey-208k4.2, Drer\znf1007" Scer\PZF1 - Xtro\znf684 "Mmus\Zfp974, Mmus\Zfp658, Mmus\Zfx, Mmus\Ikzf5, Mmus\Zfp623, Mmus\Zbtb25" "Hsap\CTCFL, Hsap\ZNF605, Hsap\ZBTB24, Hsap\ZFP37, Hsap\ZNF37A, Hsap\IKZF5, Hsap\ZFP92, Hsap\ZBTB25" FBgn0267011 CR45455 - http://flybase.org/reports/FBgn0267011 non_protein_coding_gene - - - CR45455 - CR45455 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265658 CR44465 - http://flybase.org/reports/FBgn0265658 non_protein_coding_gene - - - CR44465 - CR44465 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030745 CG4239 - http://flybase.org/reports/FBgn0030745 protein_coding_gene calcium-activated potassium channel activity ; GO:0015269 | inferred from biological aspect of ancestor with PANTHER:PTN000278842 monovalent inorganic cation transport ; GO:0015672 | inferred from electronic annotation with InterPro:IPR007866 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR007866 CG4239 IPR007866:TRIC channel CG4239 11-Aug-17 DroID_v2017_08 "Drer\tmem38b, Drer\tmem38a" - "Cele\Y57A10A.28, Cele\Y57A10A.10" "Xtro\tmem38a, Xtro\tmem38b" "Mmus\Tmem38b, Mmus\Tmem38a" "Hsap\TMEM38A, Hsap\TMEM38B" "lethal,partially lethal - majority die" FBgn0024723 Su(var)47E48A Su(var)47E48A http://flybase.org/reports/FBgn0024723 - gene - - - Su(var)47E48A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250911 CG42245 - http://flybase.org/reports/FBgn0250911 protein_coding_gene - - - CG42245 IPR027911:Domain of unknown function DUF4604 CG42245 11-Aug-17 DroID_v2017_08 Drer\zgc:77056 - Cele\T25G3.1 Xtro\kiaa1143 Mmus\1110059G10Rik Hsap\KIAA1143 FBgn0005242 l(3)R102 lethal of Roberts 102 http://flybase.org/reports/FBgn0005242 - gene - - - "l(3)102, l(3)R102" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0083040 snoRNA:Psi18S-1854c snoRNA:Psi18S-1854c http://flybase.org/reports/FBgn0083040 snoRNA_gene - - - "snoRNA:Psi18S-1854c, Psi18S-1854c, psi18S-1854c, CR34598, chrX:16979184..16979324" - CR34598 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259326 EP-319 - http://flybase.org/reports/FBgn0259326 gene - - - EP-319 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing margin,chaeta" FBgn0260806 EP3-934 - http://flybase.org/reports/FBgn0260806 gene - - - EP3-934 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010094 Su(w[a4]) Suppressor of white-apricot 4 http://flybase.org/reports/FBgn0010094 - gene - - - Su(w[a4]) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262838 CG43202 - http://flybase.org/reports/FBgn0262838 protein_coding_gene - - - "CG43202, DMG8-chr2R.26.014, CG42737, chr2R.1731" - CG43202 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011183 l(1)294-22 lethal (1) 294-22 http://flybase.org/reports/FBgn0011183 FBgn0010200 gene - - - "294-22, l(1)294-22" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032090 CG9582 - http://flybase.org/reports/FBgn0032090 protein_coding_gene dicarboxylic acid transmembrane transporter activity ; GO:0005310 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 dicarboxylic acid transport ; GO:0006835 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 CG9582 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG9582 11-Aug-17 DroID_v2017_08 Drer\slc25a21 "Scer\ODC1, Scer\ODC2" Cele\slc-25A21 Xtro\slc25a21 Mmus\Slc25a21 Hsap\SLC25A21 "viable,fertile" FBgn0051699 CG31699 - http://flybase.org/reports/FBgn0051699 protein_coding_gene - - - CG31699 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22062 E -0.490699578 0.050299163 -1.833773621 -0.143108806 0.696804445 -0.211590067 FBgn0017627 Eig45Aa Eig45Aa http://flybase.org/reports/FBgn0017627 - gene - - - "Eig45-1, Eig45Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021768 nudC nudC http://flybase.org/reports/FBgn0021768 FBgn0036664 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000270240 positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from genetic interaction with dar1 nucleus localization ; GO:0051647 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000270240 nuclear migration ; GO:0007097 | inferred from sequence or structural similarity with UniProtKB:P17624 microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Q9VVA6, CG9710, DnudC, NUDC, nudC, NudC" "IPR025934:NudC N-terminal domain, IPR007052:CS domain, IPR008978:HSP20-like chaperone" CG9710 11-Aug-17 DroID_v2017_08 "Drer\nudcd3, Drer\nudcd2, Drer\nudc" - Cele\nud-1 "Xtro\nudcd2, Xtro\nudcd3, Xtro\nudc" "Mmus\Nudcd3, Mmus\Nudc, Mmus\Nudcd2" "Hsap\NUDCD3, Hsap\NUDCD2, Hsap\NUDC" "viable,fertile" FBgn0002448 l(3)SG1 lethal (3) SG1 http://flybase.org/reports/FBgn0002448 FBgn0004706 gene - - - "l(3)dsl-4, l(3)g60L, l(3)dsl4, l(3)A4, l(3)SG1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0035526 CG1316 - http://flybase.org/reports/FBgn0035526 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg1316, CG1316" "IPR000504:RNA recognition motif domain, IPR034206:RBM45, RNA recognition motif 2, IPR034203:RBM45, RNA recognition motif 1, IPR034208:RBM45, RNA recognition motif 4, IPR034207:RBM45, RNA recognition motif 3" CG1316 11-Aug-17 DroID_v2017_08 Drer\rbm45 - - Xtro\rbm45 Mmus\Rbm45 Hsap\RBM45 "partially lethal - majority die,some die during pupal stage" FBgn0015569 alpha-Est10 alpha-Esterase-10 http://flybase.org/reports/FBgn0015569 FBgn0046454 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Esterase-10, alpha-Ests, alphaE10, aE10, K, CG1131, anon-WO0172774.144, alpha-Est10, DmalphaE10" "IPR002018:Carboxylesterase, type B, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG1131 11-Aug-17 DroID_v2017_08 "Drer\nlgn4b, Drer\ces2, Drer\nlgn1, Drer\cell, Drer\nlgn3a, Drer\cel.1, Drer\si:ch211-93f2.1, Drer\nlgn3b, Drer\nlgn2a, Drer\ces3, Drer\nlgn2b, Drer\nlgn4a" - "Cele\Y71H2AM.13, Cele\T02B5.3, Cele\B0238.7, Cele\F56C11.6, Cele\F15A8.6, Cele\T28C12.5, Cele\T28C12.4, Cele\R173.3, Cele\F07C4.12, Cele\K07C11.4, Cele\K11G9.2, Cele\F13H6.3, Cele\K11G9.3, Cele\C52A10.1, Cele\T07H6.1, Cele\K11G9.1" "Xtro\cel, Xtro\LOC100494782, Xtro\ces3, Xtro\ces2, Xtro\nlgn3, Xtro\nlgn4x, Xtro\nlgn2" "Mmus\Ces1h, Mmus\Ces2c, Mmus\Ces2h, Mmus\Ces2e, Mmus\Nlgn2, Mmus\Ces2a, Mmus\Ces2f, Mmus\Nlgn1, Mmus\Ces5a, Mmus\Ces1c, Mmus\Ces1f, Mmus\Nlgn3, Mmus\Ces1e, Mmus\Ces1d, Mmus\Ces2g, Mmus\Ces2b, Mmus\Ces4a, Mmus\Ces1b, Mmus\Ces3a, Mmus\Ces3b, Mmus\Ces1g, Mmus\Cel" "Hsap\CES4A, Hsap\NLGN4Y, Hsap\CES2, Hsap\NLGN2, Hsap\CEL, Hsap\NLGN4X, Hsap\CES5A, Hsap\NLGN1, Hsap\CES3, Hsap\CES1, Hsap\NLGN3" viable FBgn0004435 Galphaq G protein alpha q subunit http://flybase.org/reports/FBgn0004435 FBgn0004178 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000654 GTPase activity ; GO:0003924 | inferred from mutant phenotype GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with MGI:MGI:95776 G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with RGDID:620770 metarhodopsin inactivation ; GO:0016060 | inferred from mutant phenotype regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from genetic interaction with FLYBASE:GluRIinferred by curator; FB:FBgn0046113 thermotaxis ; GO:0043052 | inferred from mutant phenotype stabilization of membrane potential ; GO:0030322 | inferred from genetic interaction with Itp-r83A thermotaxis ; GO:0043052 | inferred from direct assay endocytosis ; GO:0006897 | inferred from mutant phenotype activation of phospholipase C activity ; GO:0007202 | inferred from physical interaction with norpA axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from genetic interaction with Itp-r83A phototransduction ; GO:0007602 | inferred from direct assay negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | inferred from mutant phenotype mucosal immune response ; GO:0002385 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with FLYBASE:GluRIinferred by curator; FB:FBgn0046113 rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype phospholipase C-activating dopamine receptor signaling pathway ; GO:0060158 | inferred from biological aspect of ancestor with PANTHER:PTN000026396 cellular response to carbon dioxide ; GO:0071244 | inferred from mutant phenotype activation of phospholipase C activity ; GO:0007202 | inferred from genetic interaction with rdgB inferred from genetic interaction with norpA sensory perception of smell ; GO:0007608 | inferred from mutant phenotype phototransduction ; GO:0007602 | traceable author statement phototransduction ; GO:0007602 | inferred from expression pattern inferred from mutant phenotype adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 heterotrimeric G-protein complex ; GO:0005834 | inferred from sequence or structural similarity with MGI:MGI:95776 rhabdomere ; GO:0016028 | traceable author statement rhabdomere ; GO:0016028 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay inaD signaling complex ; GO:0016027 | inferred from direct assay heterotrimeric G-protein complex ; GO:0005834 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 "dgq, Galpha49b, dGqalpha, Galpha[[q]], G[q], Gq, Galphaq, Galpha, Gqalpha, G[[alphaq]], G[[q]], DGqalpha, G[[a]]q, Gaq, G[[q]]alpha, G alpha 49B, CG17759, dGaalpha, dGqalpha-49b, dGqa-49b, Gqa-3, Galpha49B, Dgq, DmGalpha[[q]], dGqalpha-3, DGq, G[[qalpha]], dG[[q]]alpha, DGalphaq, dgqalpha, dG[[alphaq]], DGalpha[[q]], G?q, Gqalpha[[e]], Gqalphae, Gqalpha{e}, galpha49B, GNAQ/11/14, Dromel_CG17759_galpha49b_mORF, dGq, sast, Gq/11" "IPR000654:G-protein alpha subunit, group Q, IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17759 11-Aug-17 DroID_v2017_08 "Drer\gna15.4, Drer\gnaia, Drer\gnaq, Drer\si:ch211-207c7.2, Drer\gna11a, Drer\gna14, Drer\gna15.1, Drer\gnaz, Drer\gnai3, Drer\gnat2, Drer\gnao1b, Drer\gna14a, Drer\gnat1, Drer\gna11b, Drer\gnav1, Drer\gna15.2, Drer\gnai2b, Drer\gnao1a, Drer\gnai1" "Scer\GPA1, Scer\GPA2" "Cele\gpa-4, Cele\gpa-7, Cele\egl-30, Cele\odr-3, Cele\goa-1, Cele\gpa-2, Cele\gpa-1, Cele\gpa-16, Cele\gpa-3" "Xtro\gnat2, Xtro\gnaq, Xtro\gna11, Xtro\gnaz, Xtro\gnai2, Xtro\gnat1, Xtro\gnao1, Xtro\gnai3, Xtro\gnai1, Xtro\gna14, Xtro\gna15" "Mmus\Gnaz, Mmus\Gnai1, Mmus\Gna11, Mmus\Gnat3, Mmus\Gnai3, Mmus\Gnai2, Mmus\Gna14, Mmus\Gnat2, Mmus\Gnao1, Mmus\Gnaq, Mmus\Gnat1, Mmus\Gna15" "Hsap\GNA14, Hsap\GNAI1, Hsap\GNAI3, Hsap\GNAT2, Hsap\GNA15, Hsap\GNAI2, Hsap\GNAZ, Hsap\GNAT1, Hsap\GNA11, Hsap\GNAO1, Hsap\GNAT3, Hsap\GNAQ" " adult stage , spermatogenesis && adult stage " " ocellus

, retina

, testis

, adult brain

, eye

, adult head

" adult stage " proboscis | restricted

, eye

, ocellus

, medulla

, rhabdomere

, lamina

, maxillary palpus

, antennal segment 3

, photoreceptor cell

" "lethal - all die before end of first instar larval stage,some die during first instar larval stage,neurophysiology defective,visual behavior defective,recessive,behavior defective,immune response defective,thermotaxis behavior defective,viable,chemosensitive behavior defective,flightless,partially,smell perception defective,heat sensitive,sensory perception defective,somatic clone,dominant,lethal - all die before end of larval stage,some die during larval stage,lethal,wild-type,neuroanatomy defective" "photoreceptor cell,rhabdomere,photoreceptor,eye photoreceptor cell,retina,conditional,adult olfactory receptor neuron ab11a,wing,adult olfactory receptor neuron Or59b,adult olfactory receptor neuron Gr21a/63a,somatic clone,fascicle | embryonic stage,pCC neuron,commissure | embryonic stage,neuropil | embryonic stage,adult olfactory receptor neuron Or42b,adult olfactory receptor neuron Or22,heat sensitive,dMP2 neuron" DRSC07432 E 0.661768117 0.294638196 1.880932623 0.870461472 0.450598843 0.343098473 FBgn0264569 CR43941 - http://flybase.org/reports/FBgn0264569 non_protein_coding_gene - - - CR43941 - CR43941 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034819 CG9877 - http://flybase.org/reports/FBgn0034819 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE26296, CG9877" - CG9877 11-Aug-17 DroID_v2017_08 - - "Cele\nlp-33, Cele\nlp-31, Cele\nlp-29" - - - DRSC04587 I 1.537782134 -0.365227241 0.224643899 1.419732769 -0.51172772 -0.238694484 FBgn0022010 l(2)k09202 lethal (2) k09202 http://flybase.net/reports/FBgn0022010.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0266886 CR45347 - http://flybase.org/reports/FBgn0266886 non_protein_coding_gene - - - CR45347 - CR45347 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086556 MRE25 mRNA-like ncRNA in embryogenesis 25 http://flybase.org/reports/FBgn0086556 non_protein_coding_gene - - - "MRE25, RH66770" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040389 mRpL14 mitochondrial ribosomal protein L14 http://flybase.org/reports/FBgn0040389 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AA642134 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AA642134 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AA642134 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "L14, EG:BACH48C10.6, CG14048, BcDNA:RH18819, mRpL14, mRPL14" IPR000218:Ribosomal protein L14P CG14048 11-Aug-17 DroID_v2017_08 Drer\mrpl14 Scer\MRPL38 Cele\mrpl-14 Xtro\mrpl14 Mmus\Mrpl14 Hsap\MRPL14 "viable,visible" trichogen cell FBgn0261505 CR42653 - http://flybase.org/reports/FBgn0261505 pseudogene_attribute - - - "CR42653, noncoding_9454" - CR42653 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051798 CG31798 - http://flybase.org/reports/FBgn0051798 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.187, CG31798" IPR011990:Tetratricopeptide-like helical domain CG31798 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267574 CR45914 - http://flybase.org/reports/FBgn0267574 non_protein_coding_gene - - - CR45914 - CR45914 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052399 CG32399 - http://flybase.org/reports/FBgn0052399 protein_coding_gene - - - "BcDNA:RH33996, CG32399" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001655 l(1)ds9 lethal (1) discs small 9 http://flybase.org/reports/FBgn0001655 - gene - - - "l(1)d sml-9, l(1)d.sml.-9, l(1)ds9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0029144 P(3)79D P(3)79D http://flybase.org/reports/FBgn0029144 gene - - - P(3)79D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261993 CG42811 - http://flybase.org/reports/FBgn0261993 protein_coding_gene - - - "CG42811, CG18669" IPR006631:Protein of unknown function DM4/12 CG42811 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015486 l(2)46Cj lethal (2) 46Cj http://flybase.org/reports/FBgn0015486 FBgn0019713 gene - - - "O, 20.10, l(2)46CFo, l(2)46Cj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval digestive system,presumptive embryonic/larval tracheal system" FBgn0053737 snmRNA:430:CR33737 snmRNA:430:CR33737 http://flybase.org/reports/FBgn0053737 non_protein_coding_gene - - - "CR33737, snmRNA:430:CR33737" - CR33737 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030292 CG11752 - http://flybase.org/reports/FBgn0030292 protein_coding_gene - - mitochondrial respiratory chain complex I ; GO:0005747 | inferred from electronic annotation with InterPro:IPR026193 "anon-EST:Posey214, BcDNA:RH44935, CG11752" IPR026193:NADH-ubiquinone oxidoreductase flavoprotein 3 CG11752 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" trichogen cell FBgn0019702 l(2)42Bc lethal (2) 42Bc http://flybase.org/reports/FBgn0019702 - gene - - - "l(2)5CC1, 5CC1, l(2)42Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005403 l(1)10Bo lethal (1) 10Bo http://flybase.org/reports/FBgn0005403 - gene - - - "l(1)VE328, l(1)10Bo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone" FBgn0265600 kay::Dpse\kay - http://flybase.org/reports/FBgn0265600 engineered_fusion_gene - - - kay::Dpse\kay - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041603 fsco four score http://flybase.org/reports/FBgn0041603 gene molecular_function ; GO:0003674 | no biological data available meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fsco - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern,spindle & meiotic telophase I | male,contractile ring & meiotic telophase I | male,spindle & meiotic telophase II | male,contractile ring & meiotic telophase II | male,spermatid & nucleus | supernumeraryp25),spindle & meiotic telophase I | malep25),contractile ring & meiotic telophase I | malep25),spindle & meiotic telophase II | malep25),contractile ring & meiotic telophase II | malep25)" FBgn0011454 l(3)neo10 lethal (3) neo10 http://flybase.org/reports/FBgn0011454 - gene - - - l(3)neo10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060870 l(3)S047117 lethal (3) S047117 http://flybase.org/reports/FBgn0060870 gene - - - "0471/17, l(3)S047117" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0015546 spel1 spellchecker1 http://flybase.org/reports/FBgn0015546 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000432, InterPro:IPR007695, InterPro:IPR007696, InterPro:IPR007860, InterPro:IPR007861, InterPro:IPR011184 mismatched DNA binding ; GO:0030983 | inferred from electronic annotation with InterPro:IPR000432, InterPro:IPR007695, InterPro:IPR007696, InterPro:IPR007860, InterPro:IPR007861, InterPro:IPR011184 DNA binding ; GO:0003677 | non-traceable author statement" mismatch repair ; GO:0006298 | inferred from mutant phenotype postreplication repair ; GO:0006301 | inferred from sequence or structural similarity with UniProtKB:P43246 maintenance of DNA repeat elements ; GO:0043570 | inferred from mutant phenotype interstrand cross-link repair ; GO:0036297 | inferred from mutant phenotype inferred from genetic interaction with Fancd2 mismatch repair complex ; GO:0032300 | inferred from electronic annotation with InterPro:IPR032642 nucleus ; GO:0005634 | non-traceable author statement "spel, CG4215, Msh2, BG:DS01068.9, SPEL1, spel-1, spel1" "IPR000432:DNA mismatch repair protein MutS, C-terminal, IPR007695:DNA mismatch repair protein MutS-like, N-terminal, IPR007696:DNA mismatch repair protein MutS, core, IPR007860:DNA mismatch repair protein MutS, connector domain, IPR007861:DNA mismatch repair protein MutS, clamp, IPR011184:DNA mismatch repair MutS, IPR016151:DNA mismatch repair protein MutS, N-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR032642:DNA mismatch repair protein Msh2" CG4215 11-Aug-17 DroID_v2017_08 Drer\msh2 Scer\MSH2 Cele\msh-2 Xtro\msh2 Mmus\Msh2 Hsap\MSH2 viable DRSC03617 E 1.183911735 -0.362520525 -1.831481868 0.367864972 -0.135616213 -0.117266577 FBgn0013258 E(var)35 E(var)35 http://flybase.org/reports/FBgn0013258 - gene - - - E(var)35 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0020877 anon-A8 anon-A8 http://flybase.org/reports/FBgn0020877 - gene - - - "2-A8, anon-A8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0020832 l(2)PW "Pullman, Washington" http://flybase.org/reports/FBgn0020832 - gene - - - l(2)PW - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014329 l(3)ry74 lethal (3) ry74 http://flybase.org/reports/FBgn0014329 - gene - - - l(3)ry74 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015024 CkIalpha Casein kinase Ialpha http://flybase.org/reports/FBgn0015024 "FBgn0029043, FBgn0066807, FBgn0066808" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O16844 protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity" negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred by curator from GO:0032436 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein catabolic process ; GO:0030163 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay cell morphogenesis ; GO:0000902 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from direct assay regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype beta-catenin destruction complex ; GO:0030877 | inferred from sequence or structural similarity with UniProtKB:P48729 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CK1, CK1alpha, CKIalpha, CKI, CK1a, CkIa, CKIa, CG2028, CK I, dmckI, dmCK1, CkIalpha, l(1)G0492, anon-WO03040301.95, anon-WO03040301.93, ck1alpha, CKI alpha, ck1a, PKA-C, CkI alpha, Ck1alpha" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG2028 11-Aug-17 DroID_v2017_08 "Drer\ttbk1b, Drer\csnk1db, Drer\vrk1, Drer\csnk1da, Drer\ttbk1a, Drer\ttbk2b, Drer\vrk2, Drer\csnk1e, Drer\csnk1a1, Drer\vrk3" "Scer\YCK1, Scer\HRR25, Scer\YCK3, Scer\YCK2" "Cele\Y39G8C.2, Cele\Y111B2A.27, Cele\K09E4.1, Cele\kin-20, Cele\kin-19" "Xtro\vrk3, Xtro\csnk1a1, Xtro\ttbk2, Xtro\csnk1d, Xtro\vrk2, Xtro\vrk1, Xtro\csnk1e" "Mmus\Csnk1e, Mmus\Vrk3, Mmus\Vrk2, Mmus\Ttbk1, Mmus\Vrk1, Mmus\Csnk1d, Mmus\Ttbk2, Mmus\Csnk1a1" "Hsap\VRK1, Hsap\TTBK2, Hsap\CSNK1A1, Hsap\LOC400927-CSNK1E, Hsap\CSNK1E, Hsap\CSNK1A1L, Hsap\VRK3, Hsap\CSNK1D, Hsap\TTBK1, Hsap\VRK2" "visible,somatic clone,lethal,behavior defective,recessive,female sterile,partially lethal - majority die,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "eye,somatic clone,eye disc,wing,embryonic/first instar larval cuticle,ventral nerve cord commissure,longitudinal connective,embryonic epidermis,wing margin bristle,ectopic,embryonic/larval neuroblast,ganglion mother cell,synapse,neuromuscular junction" DRSC22609 K 0.226418346 0.061498999 -0.219256744 1.367663992 1.505405909 1.157408614 FBgn0005717 l(1)TK123 lethal (1) TK123 http://flybase.org/reports/FBgn0005717 - gene - - - "l123, l(1)TK123" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0004577 Pxd Peroxidase http://flybase.org/reports/FBgn0004577 - protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 peroxidase activity ; GO:0004601 | inferred from sequence or structural similarity oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 phagocytosis ; GO:0006909 | inferred from mutant phenotype eggshell chorion assembly ; GO:0007306 | non-traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from mutant phenotype chorion ; GO:0042600 | inferred from direct assay "CG3477, Dpxd, PO, DmPO, Pxd" "IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal, IPR029585:Peroxidase, insect" CG3477 11-Aug-17 DroID_v2017_08 "Drer\ptgs2b, Drer\igsf9bb, Drer\tpo, Drer\ptgs1, Drer\ptgs2a" - "Cele\skpo-3, Cele\mlt-7, Cele\C46A5.4, Cele\pxn-1, Cele\K10B4.1, Cele\T06D8.10, Cele\F09F3.5, Cele\R08F11.7" "Xtro\epx, Xtro\pxdn, Xtro\tpo, Xtro\ptgs1, Xtro\ptgs2, Xtro\mpo" "Mmus\Epx, Mmus\Lpo, Mmus\Ptgs1, Mmus\Ptgs2, Mmus\Pxdn, Mmus\Tpo, Mmus\Mpo" "Hsap\PTGS2, Hsap\PXDN, Hsap\LPO, Hsap\PXDNL, Hsap\PTGS1, Hsap\TPO, Hsap\MPO, Hsap\EPX" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0002313 l(3)85Ad lethal (3) 85Ad http://flybase.org/reports/FBgn0002313 - gene - - - "L4, l(3)85Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037182 ArfGAP3 ADP-ribosylation factor GTPase activating protein 3 http://flybase.org/reports/FBgn0037182 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 GTPase activator activity ; GO:0005096 | inferred from sequence model compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from sequence model lateral inhibition ; GO:0046331 | inferred from mutant phenotype adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG6838, ArfGAP3, dArfGAP3, arfgap1, AG2" IPR001164:Arf GTPase activating protein CG6838 11-Aug-17 DroID_v2017_08 "Drer\arfgap2, Drer\arfgap3, Drer\terfa" "Scer\GLO3, Scer\SPS18" "Cele\F07F6.4, Cele\cnt-2" Xtro\arfgap2 "Mmus\Arfgap3, Mmus\Arfgap2" "Hsap\ARFGAP3, Hsap\ARFGAP2" "viable,visible" "chaeta,ommatidium,retina" FBgn0250754 CG42232 - http://flybase.org/reports/FBgn0250754 protein_coding_gene - - - "CG42232, clone 1.14, anon-EST:Liang-1.14, CG14896, CG14897" IPR008984:SMAD/FHA domain CG42232 11-Aug-17 DroID_v2017_08 Drer\mki67 - Cele\ret-1 - "Mmus\Cmya5, Mmus\Ank2, Mmus\Rtn4" "Hsap\RTN3, Hsap\RTN4, Hsap\MAP1A" FBgn0046654 anon-38D.10 anon-38D.10 http://flybase.org/reports/FBgn0046654 gene - - - "38D.10, anon-38D.10" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000031 AcpGI Accessory gland protein G-I http://flybase.org/reports/FBgn0000031 - gene - - - "AcpG, Acp-g1, AcpGI" - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0005675 Dia2 Diaphorase 2 http://flybase.org/reports/FBgn0005675 - gene dihydrolipoyl dehydrogenase activity ; GO:0004148 | inferred from direct assay - - "DIA-2, Dia2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058409 CG40409 - http://flybase.org/reports/FBgn0058409 protein_coding_gene - - - CG40409 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038654 CG14298 - http://flybase.org/reports/FBgn0038654 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG14298 "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG14298 11-Aug-17 DroID_v2017_08 Drer\tfpia - "Cele\C54D10.10, Cele\apl-1, Cele\T21D12.12, Cele\K11D12.6, Cele\piit-1" - Mmus\App Hsap\APP viable FBgn0066071 Su(var)2-15 Su(var)2-15 http://flybase.org/reports/FBgn0066071 gene - - - Su(var)2-15 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001479 l(1)9Fg lethal (1) 9Fg http://flybase.org/reports/FBgn0001479 - gene - - - "l(1)BP3, l(1)v5, l(1)v40, l(1)v363, l(1)v207, l(1)v205, l(1)v172, l(1)v103, l(1)9Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage" FBgn0011811 l(3)s3246 lethal (3) s3246 http://flybase.org/reports/FBgn0011811 - gene - - - l(3)s3246 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065045 spd slow-phase-defective http://flybase.org/reports/FBgn0065045 gene - - - spd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004995 crisp crisp http://flybase.org/reports/FBgn0004995 - gene - - - "crisp, cr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable" macrochaeta FBgn0022979 rrpB reduced receptor potential B http://flybase.org/reports/FBgn0022979 - gene - - - rrpB - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031773 Fbw5 F-box and WD repeat domain containing 5 http://flybase.org/reports/FBgn0031773 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9XYZ5 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with UniProtKB:Q969U6 protein ubiquitination ; GO:0016567 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000470116 positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | traceable author statement SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000470116 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model Cul4-RING E3 ubiquitin ligase complex ; GO:0080008 | inferred from sequence or structural similarity with HGNC:13613 "dFbw5, Fbw5, CG9144, FBgn 31773, FBXW2" "IPR001680:WD40 repeat, IPR001810:F-box domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain" CG9144 11-Aug-17 DroID_v2017_08 Drer\fbxw5 Scer\UFO1 - Xtro\fbxw5 Mmus\Fbxw5 Hsap\FBXW5 "viable,visible" "chaeta,supernumerary" DRSC29431 K 0.708787475 0.142056538 0.929483605 -0.69605949 1.52389324 -0.083941674 FBgn0029860 CG15891 - http://flybase.org/reports/FBgn0029860 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32918, CG15891, CG15892" IPR023340:UMA domain CG15891 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0259329 C573 - http://flybase.org/reports/FBgn0259329 gene - - - C573 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin,chaeta" FBgn0040687 CG14645 - http://flybase.org/reports/FBgn0040687 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14645 IPR002557:Chitin binding domain CG14645 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038292 CG3987 - http://flybase.org/reports/FBgn0038292 protein_coding_gene - mesoderm development ; GO:0007498 | inferred from expression pattern - "CG3987, anon-WO0140519.215" - CG3987 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0266802 CR45264 - http://flybase.org/reports/FBgn0266802 non_protein_coding_gene - - - CR45264 - CR45264 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013612 l(3)L0021 lethal (3) L0021 http://flybase.org/reports/FBgn0013612 - gene - - - l(3)L0021 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045770 S-Lap3 Sperm-Leucylaminopeptidase 3 http://flybase.org/reports/FBgn0045770 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "CG8040, BEST:LP10167, anon-WO0140519.83, S-Lap3, CG32063, S-LAP 3, lincRNA.S4635" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG32063 11-Aug-17 DroID_v2017_08 "Drer\zgc:152830, Drer\rfwd2, Drer\lap3, Drer\npepl1" - "Cele\lap-2, Cele\lap-1" "Xtro\rfwd2, Xtro\lap3" "Mmus\Rfwd2, Mmus\Npepl1, Mmus\Lap3" "Hsap\NPEPL1, Hsap\LAP3" viable FBgn0027507 CG1344 - http://flybase.org/reports/FBgn0027507 - protein_coding_gene kinase activity ; GO:0016301 | NOT inferred from sequence or structural similarity with HGNC:19285 biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:19285 "BcDNA:LD22679, CG1344" "IPR016024:Armadillo-type fold, IPR021133:HEAT, type 2, IPR011009:Protein kinase-like domain, IPR011989:Armadillo-like helical" CG1344 11-Aug-17 DroID_v2017_08 "Drer\scyl1, Drer\scyl3" Scer\CEX1 - "Xtro\scyl1, Xtro\scyl3" "Mmus\Scyl1, Mmus\Scyl3" "Hsap\SCYL3, Hsap\CDK3, Hsap\SCYL1, Hsap\CDK2" FBgn0000873 fs(1)M70 female sterile (1) M70 http://flybase.org/reports/FBgn0000873 - gene - - - fs(1)M70 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0051830 CG31830 - http://flybase.org/reports/FBgn0051830 protein_coding_gene - - - CG31830 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011721 TB9-3 TB9-3 http://flybase.org/reports/FBgn0011721 - gene - - - TB9-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266875 CR45336 - http://flybase.org/reports/FBgn0266875 non_protein_coding_gene - - - CR45336 - CR45336 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051810 CG31810 - http://flybase.org/reports/FBgn0051810 protein_coding_gene - - - "BcDNA:RE06583, CG31810" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG31810 11-Aug-17 DroID_v2017_08 "Drer\hsd20b2, Drer\hsd17b3, Drer\hsd17b12b, Drer\hsd17b12a, Drer\hsdl1" Scer\IFA38 "Cele\stdh-2, Cele\stdh-3, Cele\stdh-1, Cele\let-767, Cele\stdh-4, Cele\dhs-27, Cele\dhs-5" "Xtro\hsdl1, Xtro\LOC100497556, Xtro\hsd17b12" "Mmus\Hsd17b3, Mmus\Hsd17b12, Mmus\Hsdl1" "Hsap\HSD17B3, Hsap\HSD17B12, Hsap\HSDL1" FBgn0035164 CG13901 - http://flybase.org/reports/FBgn0035164 protein_coding_gene - - - CG13901 IPR026224:Protein DPCD CG13901 11-Aug-17 DroID_v2017_08 Drer\dpcd - - Xtro\dpcd Mmus\Dpcd Hsap\DPCD viable FBgn0062570 Mod(var)E1451 Mod(var)E1451 http://flybase.org/reports/FBgn0062570 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1451, Mod(var)E1451" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0259379 C767 - http://flybase.org/reports/FBgn0259379 gene - - - C767 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0035295 Cnb Centrobin http://flybase.org/reports/FBgn0035295 protein_coding_gene molecular_function ; GO:0003674 | no biological data available interphase microtubule organizing center assembly ; GO:0031024 | inferred from mutant phenotype protein localization to centrosome ; GO:0071539 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from sequence or structural similarity with HGNC:29616 centriole ; GO:0005814 | inferred from direct assay "cDNA C, anon-62BCa, CG5690, Cnb, cnb" - CG5690 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-1o7.3, Drer\smc2" Scer\SMC2 "Cele\smc-4, Cele\M151.4, Cele\F14H3.4, Cele\F14H3.5" - "Mmus\Shtn1, Mmus\Golga2, Mmus\Swap70, Mmus\Smc2, Mmus\Hmmr, Mmus\Cntrob" "Hsap\CNTROB, Hsap\SHTN1, Hsap\SMC2" "mitotic cell cycle defective,viable" "centrioleED4284),embryonic/larval neuroblast,embryonic/larval neuroblast | larval stage,centrosomeunspecified,centriole" FBgn0265461 jurka - http://flybase.org/reports/FBgn0265461 gene - - - jurka - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0265843 CR44632 - http://flybase.org/reports/FBgn0265843 non_protein_coding_gene - - - "lincRNA.355, CR44632" - CR44632 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085376 CG34347 - http://flybase.org/reports/FBgn0085376 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity actomyosin structure organization ; GO:0031032 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 cytoskeleton ; GO:0005856 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 "CG11339, CG34347, LP8211, CG15566, EST:LP08211" "IPR000299:FERM domain, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019748:FERM central domain, IPR018980:FERM, C-terminal PH-like domain, IPR019749:Band 4.1 domain, IPR018979:FERM, N-terminal, IPR029071:Ubiquitin-related domain, IPR014847:FERM adjacent (FA)" CG34347 11-Aug-17 DroID_v2017_08 "Drer\frmd5, Drer\epb41l4a, Drer\epb41l4b, Drer\frmd3, Drer\LOC570903, Drer\frmd4ba" - Cele\frm-4 "Xtro\frmd5, Xtro\epb41l4a, Xtro\frmd3" "Mmus\Frmd3, Mmus\Frmd5, Mmus\Epb41l4a" "Hsap\FRMD5, Hsap\FRMD4A, Hsap\C1orf106, Hsap\EPB41L4A, Hsap\FRMD3, Hsap\FRMD4B" viable FBgn0265438 orb::orb2 - http://flybase.org/reports/FBgn0265438 engineered_fusion_gene - - - orb::orb2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010128 l(1)ts445b lethal (1) ts445b http://flybase.org/reports/FBgn0010128 - gene - - - l(1)ts445b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0052312 tRNA:Cys-GCA-2-1 transfer RNA:Cysteine-GCA 2-1 http://flybase.org/reports/FBgn0052312 tRNA_gene UGC codon-amino acid adaptor activity ; GO:0033414 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033414 cytosol ; GO:0005829 | inferred by curator from GO:0033414 "AE002584.trna12-CysGCA, tRNA:C:GCA:AE002584-a, CR32312, chr3L.trna12-CysGCA, tRNA:Cys-GCA-2-1, tRNA:CR32312, tRNA-Cys-GCA-2-1, UGC" - CR32312 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250742 l(3)S051513 lethal (3) S051513 http://flybase.org/reports/FBgn0250742 gene - - - "l(3)S051513, l(3)s051513" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262115 CG17683 - http://flybase.org/reports/FBgn0262115 protein_coding_gene molecular_function ; GO:0003674 | no biological data available iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with UniProtKB:Q9H6Q4 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG17683, NC38, l(2)NC38, NC70, l(2)NC70, NC37, l(2)NC37, NAR1p" "IPR003149:Iron hydrogenase, small subunit, IPR004108:Iron hydrogenase, large subunit, C-terminal, IPR009016:Iron hydrogenase" CG17683 11-Aug-17 DroID_v2017_08 "Drer\narf, Drer\narfl" Scer\NAR1 Cele\oxy-4 "Xtro\narf, Xtro\narfl" "Mmus\Narf, Mmus\Narfl" "Hsap\NARFL, Hsap\NARF" FBgn0005370 wh whiskers http://flybase.org/reports/FBgn0005370 - gene - - - wh - - 11-Aug-17 DroID_v2017_08 - - - - - - visible vibrissae FBgn0023467 anon-56Ca anon-56Ca http://flybase.org/reports/FBgn0023467 - gene - - - anon-56Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male FBgn0051875 CG31875 - http://flybase.org/reports/FBgn0051875 protein_coding_gene "transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN000412750 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001043031" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000412750 transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcriptional repressor complex ; GO:0017053 | inferred from biological aspect of ancestor with PANTHER:PTN000412750 "CG5831, BcDNA:AT29184, CG31875, Desr" IPR000949:ELM2 domain CG31875 11-Aug-17 DroID_v2017_08 "Drer\ddx42, Drer\ddx46, Drer\rcor1, Drer\rcor2, Drer\rcor3" Scer\PRP5 "Cele\spr-1, Cele\rcor-1" "Xtro\ddx46, Xtro\rcor3, Xtro\rcor1, Xtro\rcor2, Xtro\ddx42" "Mmus\Rcor3, Mmus\Rcor1, Mmus\Ddx42, Mmus\Ddx46, Mmus\Rcor2" "Hsap\DDX46, Hsap\RCOR1, Hsap\DDX42, Hsap\RCOR3, Hsap\RCOR2" viable FBgn0265483 BG02419 - http://flybase.org/reports/FBgn0265483 gene - - - BG02419 - - 11-Aug-17 DroID_v2017_08 - - - - - - sleep defective FBgn0001555 l(1)19Ba lethal (1) 19Ba http://flybase.org/reports/FBgn0001555 - gene - - - l(1)19Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022098 l(2)k07204 lethal (2) k07204 http://flybase.org/reports/FBgn0022098 - gene - - - l(2)k07204 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028833 Dak1 Dak1 http://flybase.org/reports/FBgn0028833 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850 cytidylate kinase activity ; GO:0004127 | inferred from direct assay uridylate kinase activity ; GO:0009041 | inferred from direct assay pyrimidine nucleotide biosynthetic process ; GO:0006221 | inferred from electronic annotation with InterPro:IPR006266 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from sequence or structural similarity with SGD:S000001507 nucleobase-containing compound metabolic process ; GO:0006139 | inferred from sequence or structural similarity with SGD:S000001507 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000001507 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000001507 "CG6092, Dak1, Dm.UMP-CMP kinase, dak1, Dak1L, anon-WO0118547.320" "IPR000850:Adenylate kinase/UMP-CMP kinase, IPR006266:UMP-CMP kinase, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033690:Adenylate kinase, conserved site" CG6092 11-Aug-17 DroID_v2017_08 "Drer\ak5l, Drer\ak1, Drer\cmpk, Drer\ak5, Drer\si:ch211-199m3.4" Scer\URA6 "Cele\F38E11.6, Cele\F40F8.1, Cele\F38B2.4, Cele\C29F7.3" "Xtro\ak1, Xtro\cmpk1" "Mmus\Cmpk1, Mmus\Ak5, Mmus\Ak9, Mmus\Ak1, Mmus\Ak8" "Hsap\AK9, Hsap\CMPK1, Hsap\AK1, Hsap\AK5" "viable,fertile" FBgn0024352 Hop Hsp70/Hsp90 organizing protein http://flybase.org/reports/FBgn0024352 FBgn0022263 protein_coding_gene - - - "dHop, dmSTI1, EP(2)0418, dhop, dSTI1, l(2)k00616, Sti1, CG2720, Hop, HOP, hop" "IPR006636:Heat shock chaperonin-binding, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1" CG2720 11-Aug-17 DroID_v2017_08 "Drer\sgut1, Drer\stip1, Drer\ttc12, Drer\si:dkey-33c12.4, Drer\zgc:123010" Scer\STI1 Cele\sti-1 "Xtro\sugt1, Xtro\stip1" "Mmus\Sugt1, Mmus\Stip1, Mmus\Spata16, Mmus\Ttc12" "Hsap\SPATA16, Hsap\SUGT1, Hsap\TTC12, Hsap\STIP1, Hsap\TTC28, Hsap\TTC31" "lethal,recessive,wild-type,viable" FBgn0032350 CG6287 - http://flybase.org/reports/FBgn0032350 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR006139 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" - "CG6287, GH26" "IPR006139:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040:NAD(P)-binding domain, IPR029752:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1" CG6287 11-Aug-17 DroID_v2017_08 "Drer\zgc:136929, Drer\ctbp2a, Drer\ctbp1, Drer\phgdh" "Scer\SER3, Scer\SER33" "Cele\ctbp-1, Cele\C31C9.2" Xtro\phgdh "Mmus\Ctbp2, Mmus\Phgdh, Mmus\Ctbp1" "Hsap\PHGDH, Hsap\CTBP1, Hsap\CTBP2" viable FBgn0015904 ara araucan http://flybase.org/reports/FBgn0015904 FBgn0014195 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" "equator specification ; GO:0045317 | traceable author statement negative regulation of growth ; GO:0045926 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype notum cell fate specification ; GO:0035310 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | non-traceable author statement imaginal disc-derived wing vein specification ; GO:0007474 | inferred from genetic interaction with rho inferred from genetic interaction with caup muscle cell fate commitment ; GO:0042693 | inferred from genetic interaction with caup" nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:8632 inferred by curator from GO:0003705 "ara, Iro-C, IRO-C, iro, Iro, iro-C, CG10571, Ara, IroC" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR008422:Homeobox KN domain, IPR017970:Homeobox, conserved site, IPR015943:WD40/YVTN repeat-like-containing domain, IPR003893:Iroquois-class homeodomain protein" CG10571 11-Aug-17 DroID_v2017_08 "Drer\irx1a, Drer\irx4a, Drer\meis3, Drer\irx5a, Drer\pknox1.1, Drer\irx1b, Drer\pknox1.2, Drer\mkxa, Drer\irx5b, Drer\pknox2, Drer\irx6a, Drer\irx2a, Drer\meis1a, Drer\meis2a, Drer\irx3a, Drer\irx4b, Drer\tgif1, Drer\irx3b, Drer\irx7, Drer\meis2b" "Scer\TOS8, Scer\HMLALPHA2, Scer\MATALPHA2, Scer\CUP9, Scer\HMRA2" Cele\irx-1 "Xtro\irx5, Xtro\meis3, Xtro\tgif2, Xtro\irx4, Xtro\tgif1, Xtro\irx2, Xtro\irx3, Xtro\meis1, Xtro\irx1, Xtro\mkx, Xtro\meis2, Xtro\pknox2" "Mmus\Irx1, Mmus\Irx2, Mmus\Meis2, Mmus\Irx5, Mmus\Meis1, Mmus\Pknox1, Mmus\Tgif1, Mmus\Irx6, Mmus\Irx4, Mmus\Pknox2, Mmus\Tgif2lx1, Mmus\Meis3, Mmus\Tgif2lx2, Mmus\Tgif2, Mmus\Irx3, Mmus\Mkx" "Hsap\IRX6, Hsap\MEIS1, Hsap\TGIF2, Hsap\IRX4, Hsap\IRX2, Hsap\IRX5, Hsap\TGIF2LY, Hsap\MKX, Hsap\TGIF2-C20orf24, Hsap\PKNOX1, Hsap\IRX3, Hsap\PKNOX2, Hsap\TGIF1, Hsap\TGIF2LX, Hsap\MEIS2, Hsap\IRX1" " larval stage | third instar , larval stage , embryonic stage -- adult stage , embryonic stage | late , larval stage | second instar , embryonic stage | stage >=11 " " wing vein L5

, dorsal metathoracic disc

, imaginal disc

, embryonic/larval proventriculus

, wing vein L1

, procephalic segment

, mesothoracic pleurum

, tegula

, epidermis | lateral

, alula

, ventral nerve cord

, wing vein L3

" "lethal,recessive,neuroanatomy defective,viable,visible,partially lethal - majority die,female sterile,male sterile,planar polarity defective,lethal - all die before end of larval stage,some die during larval stage,some die during pupal stage" "wing vein L5,alula,dorsal multidendritic neuron ddaD,abdominal anterior ventral multidendritic neuron vdaa,wing,macrochaeta,macrochaeta & adult thorax,eye,macrochaeta & scutum,microchaeta,mesothoracic segment,notopleural suture,scutellum,wing vein L1,wing vein L3,sensillum campaniformium of dorsal radius,campaniform sensillum of anterior crossvein,twin sensillum of margin 1,twin sensillum of margin 2,wing hinge,axillary sclerite,dorsal margin photoreceptor,ectopic,ommatidium,maxillary palpus,rostral membrane,adult cuticle,eye disc,somatic clone,photoreceptor cell,antenna,arista,vibrissae,scutum & microchaeta | medial-537.4,wing vein L2,posterior supraalar bristle,anterior supraalar bristle,posterior scutellar bristle,wing vein,sense organ & wing | anteriorC-765,anterior postalar bristle,mesothoracic tergum,dorsal,ventral,embryonic/larval brain" FBgn0063903 Neurodegeneration-9 Neurodegeneration 9 http://flybase.org/reports/FBgn0063903 gene - - - "ND10, Neurodegeneration-9, ND9" - - 11-Aug-17 DroID_v2017_08 - - - - - - central nervous system FBgn0026244 fret free thinker http://flybase.org/reports/FBgn0026244 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "thag, fret" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028629 ksh-18 ksh-18 http://flybase.org/reports/FBgn0028629 gene - - - ksh-18 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261692 T:CBD-WASp Cdc42-binding domain of WASp http://flybase.org/reports/FBgn0261692 engineered_tag - - - "T:CBD-WASp, T:CBD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030952 CG12609 - http://flybase.org/reports/FBgn0030952 protein_coding_gene "transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 basal RNA polymerase II transcription machinery binding ; GO:0001099 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 CG12609 IPR006578:MADF domain CG12609 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035508 CG15005 - http://flybase.org/reports/FBgn0035508 protein_coding_gene - - - CG15005 IPR032059:Mucin-like domain CG15005 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-103b11.2, Drer\triobpa, Drer\triobpb" - Cele\hpo-34 "Xtro\triobp, Xtro\mprip" "Mmus\Triobp, Mmus\Mprip" Hsap\MAGEC1 viable FBgn0086129 snama something that sticks like glue http://flybase.org/reports/FBgn0086129 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001878, InterPro:IPR014891 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:9889" neurogenesis ; GO:0022008 | inferred from mutant phenotype cell proliferation involved in compound eye morphogenesis ; GO:0035736 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:9889 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR014891 cellular_component ; GO:0005575 | no biological data available "CG3231, l(2)rQ313, BcDNA:LD21643, snama, SNAMA, BCDNA:LD21643, mnm, Snama, FBgn0086129" "IPR001878:Zinc finger, CCHC-type, IPR001841:Zinc finger, RING-type, IPR014891:DWNN domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR025829:Zinc knuckle CX2CX3GHX4C" CG3231 11-Aug-17 DroID_v2017_08 "Drer\LOC100002202, Drer\si:rp71-45g20.11, Drer\zgc:77614, Drer\LOC561873, Drer\rbbp6, Drer\zgc:91850, Drer\si:dkey-27d5.10, Drer\si:rp71-45g20.10, Drer\LOC100004867, Drer\si:dkey-23f9.8, Drer\LOC100006889, Drer\LOC103911531, Drer\si:dkey-23f9.7, Drer\LOC100329917, Drer\LOC100329755, Drer\LOC100005207, Drer\LOC100536005, Drer\LOC100005013, Drer\si:dkey-23f9.13, Drer\LOC100535429, Drer\si:dkey-27d5.14, Drer\si:busm1-37i06.3, Drer\LOC108179082, Drer\LOC100006815, Drer\LOC101882874, Drer\si:dkey-23f9.6, Drer\si:rp71-45g20.4, Drer\LOC108190973, Drer\LOC100535555, Drer\si:dkey-23f9.11, Drer\LOC100006401, Drer\si:dkey-23f9.12, Drer\LOC100007007, Drer\zgc:174354, Drer\LOC100005157, Drer\LOC103909946, Drer\zgc:173948, Drer\LOC100007069, Drer\si:dkey-27d5.5, Drer\LOC100004392, Drer\LOC100148590, Drer\si:ch211-156l18.6, Drer\si:dkey-23f9.9, Drer\si:dkey-27d5.4, Drer\zgc:174355, Drer\zgc:174358, Drer\LOC100329825, Drer\zgc:174353" Scer\MPE1 Cele\rbpl-1 "Xtro\aff4, Xtro\rbbp6" "Mmus\Aff4, Mmus\Rbbp6" "Hsap\AFF4, Hsap\RBBP6" FBgn0267667 CR46005 - http://flybase.org/reports/FBgn0267667 non_protein_coding_gene - - - CR46005 - CR46005 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016720 Reg-6 Rhythmically expressed gene 6 http://flybase.org/reports/FBgn0016720 - gene - - - "Dreg-6, Reg-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage FBgn0022225 l(2)k03201 lethal (2) k03201 http://flybase.org/reports/FBgn0022225 - gene - - - l(2)k03201 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" crystal cell FBgn0031469 CG18558 - http://flybase.org/reports/FBgn0031469 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 "CG18558, dC1GalT3" IPR003378:Fringe-like CG18558 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-202e17.1, Drer\c1galt1b, Drer\LOC564281, Drer\c1galt1a, Drer\c1galt1c1" - "Cele\W09D10.5, Cele\C17A2.3, Cele\C16D9.6, Cele\E03H4.3, Cele\C02H6.1, Cele\Y38C1AB.1, Cele\F56H6.1, Cele\Y38C1AB.5, Cele\C38H2.2, Cele\T09E11.12, Cele\bus-4, Cele\F37A4.3" "Xtro\LOC100496837, Xtro\c1galt1" "Mmus\C1galt1, Mmus\C1galt1c1" "Hsap\C1GALT1C1, Hsap\C1GALT1" viable FBgn0040694 CG14974 - http://flybase.org/reports/FBgn0040694 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14974 - CG14974 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264893 CR44084 - http://flybase.org/reports/FBgn0264893 non_protein_coding_gene - - - CR44084 - CR44084 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000080 an ancon http://flybase.org/reports/FBgn0000080 - gene - - - an - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "leg,wing,macrochaeta & abdomen,eye,tergite" FBgn0028599 l(2)W9 lethal (2) W9 http://flybase.org/reports/FBgn0028599 gene - - - "l(2R)W9, l(2)W9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005432 fliK flightless K http://flybase.org/reports/FBgn0005432 "FBgn0000673, FBgn0001865" gene - - - "EM15, l(1)9Fc, fliK" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,flightless" FBgn0052027 CR32027 - http://flybase.org/reports/FBgn0052027 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE02231, CG32027, CR32027" - CR32027 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0050382 CG30382 - http://flybase.org/reports/FBgn0050382 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 molecular_function ; GO:0003674 | no biological data available" cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000002979 positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from sequence or structural similarity with SGD:S000002979" "CG30382, 30382, Prosalpha1R, Prosalpha6, Pros-alpha1" "IPR001353:Proteasome, subunit alpha/beta, IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR023332:Proteasome alpha-type subunit, IPR034642:Proteasome subunit alpha6, IPR029055:Nucleophile aminohydrolases, N-terminal" CG30382 11-Aug-17 DroID_v2017_08 "Drer\psma6l, Drer\psma6b, Drer\psma6a" Scer\SCL1 Cele\pas-1 Xtro\psma6 Mmus\Psma6 Hsap\PSMA6 DRSC29087 IEK -2.335959773 -2.87074977 -1.812772388 -1.150262632 2.154068764 1.458062574 FBgn0002434 l(3)KX209 lethal (3) KX209 http://flybase.org/reports/FBgn0002434 - gene - - - l(3)KX209 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal peripheral nervous system FBgn0016801 l(1)K3 lethal (1) K3 http://flybase.org/reports/FBgn0016801 - gene - - - "l(1)K3, K3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259952 Sfp24Bb Seminal fluid protein 24Bb http://flybase.org/reports/FBgn0259952 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp24Bb, CG42462, SFP24BB" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42462 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061508 l(2)24Ab lethal (2) 24Ab http://flybase.org/reports/FBgn0061508 gene - - - l(2)24Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004158 l(2)51Ea lethal (2) 51Ea http://flybase.org/reports/FBgn0004158 - gene - - - l(2)51Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,lethal,polyphasic,heat sensitive,lethal - all die before end of larval stage,some die during larval stage" FBgn0011224 heph hephaestus http://flybase.org/reports/FBgn0011224 "FBgn0010798, FBgn0011433, FBgn0029138, FBgn0039884, FBgn0039885, FBgn0051000" protein_coding_gene "translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from mutant phenotype mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay" mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR006536 spermatid development ; GO:0007286 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype negative regulation of oskar mRNA translation ; GO:0007319 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG31000, CG2290, dmPTB, PTB, Ptb, CG2094, ema, ptb, l(3)03429, l(3)j11B9, heph, HEPH, Heph, dPTB, hnRNP I, DmPTB" "IPR000504:RNA recognition motif domain, IPR006536:HnRNP-L/PTB, IPR015943:WD40/YVTN repeat-like-containing domain" CG31000 11-Aug-17 DroID_v2017_08 "Drer\ptbp3, Drer\ptbp1a, Drer\ptbp2a, Drer\ptbp2b, Drer\ptbp1b" Scer\MRD1 Cele\ptb-1 "Xtro\ptbp2, Xtro\ptbp1, Xtro\ptbp3" "Mmus\Ptbp3, Mmus\Ptbp2, Mmus\Ptbp1" "Hsap\PTBP1, Hsap\PTBP3, Hsap\PTBP2" "viable,fertile,learning defective,lethal,male sterile,recessive,heat sensitive,visible,somatic clone,mitotic cell cycle defective,female fertile" "wing,testis,spermatozoon,individualization stage spermatid,spermatid cyst,elongation stage spermatid,germline cell,male,macrochaeta,wing vein,cell autonomous,somatic clone,wing margin,ectopic,embryonic head,germline clone,trichogen cell,mesothoracic tergum" DRSC14085 IE -0.910237949 -1.539103529 -0.008490841 -1.831969216 -0.369370127 0.374456334 FBgn0263333 CR43414 - http://flybase.org/reports/FBgn0263333 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "CR43414, lincRNA.205" - CR43414 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051352 Unc-115a Uncoordinated 115a http://flybase.org/reports/FBgn0051352 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 actin binding ; GO:0003779 | inferred from sequence or structural similarity with HGNC:12690 cytoskeleton organization ; GO:0007010 | inferred from electronic annotation with InterPro:IPR003128 photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype - "CG9489, anon-WO0140519.21, unc-115, CG31352, dunc-115, Unc-115a, Dunc-115" "IPR001781:Zinc finger, LIM-type, IPR003128:Villin headpiece" CG31352 11-Aug-17 DroID_v2017_08 "Drer\ablim1b, Drer\ablim3, Drer\ablim1a, Drer\dmtn, Drer\ablim2" - Cele\unc-115 "Xtro\dmtn, Xtro\ablim3, Xtro\ablim2" "Mmus\Ablim3, Mmus\Dmtn, Mmus\Ablim1, Mmus\Ablim2" "Hsap\DMTN, Hsap\ABLIM2, Hsap\ABLIM1, Hsap\ABLIM3" "viable,visible,fertile,neuroanatomy defective" "mesothoracic tergum,lamina plexus,eye photoreceptor cell,segmental nerve,embryonic ventral neuromere,longitudinal connective" FBgn0040609 CG3348 - http://flybase.org/reports/FBgn0040609 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG3348 IPR002557:Chitin binding domain CG3348 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC15480 I 1.570023063 -0.125233726 -1.274720235 0.185065206 0.245618456 -0.329843495 FBgn0267476 CR45826 - http://flybase.org/reports/FBgn0267476 non_protein_coding_gene - - - CR45826 - CR45826 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053158 CG33158 - http://flybase.org/reports/FBgn0053158 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795" - cytosol ; GO:0005829 | inferred from direct assay "CG10162, CG4638, CG33158" "IPR000640:Translation elongation factor EFG, V domain, IPR000795:Transcription factor, GTP-binding domain, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR005225:Small GTP-binding protein domain, IPR009000:Translation protein, beta-barrel domain, IPR009022:Elongation factor G, III-V domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold" CG33158 11-Aug-17 DroID_v2017_08 Drer\eftud1 Scer\RIA1 Cele\K10C3.5 Xtro\efl1 Mmus\Efl1 Hsap\EFL1 "viable,fertile,song defective" FBgn0053367 5SrRNA:CR33367 5SrRNA:CR33367 http://flybase.org/reports/FBgn0053367 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33367, 5SrRNA:CR33367" - CR33367 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060754 l(3)S064316a lethal (3) S064316a http://flybase.org/reports/FBgn0060754 gene - - - "0643/16, l(3)S064316a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031279 CG3544 - http://flybase.org/reports/FBgn0031279 protein_coding_gene xylulokinase activity ; GO:0004856 | inferred from biological aspect of ancestor with PANTHER:PTN000023215 xylulokinase activity ; GO:0004856 | inferred from sequence or structural similarity with HGNC:12839 xylulose metabolic process ; GO:0005997 | inferred from biological aspect of ancestor with PANTHER:PTN000023215 xylulose metabolic process ; GO:0005997 | inferred from sequence or structural similarity with HGNC:12839 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:12839 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000023213 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:12839 CG3544 "IPR018484:Carbohydrate kinase, FGGY, N-terminal, IPR018485:Carbohydrate kinase, FGGY, C-terminal" CG3544 11-Aug-17 DroID_v2017_08 Drer\xylb Scer\XKS1 Cele\R08D7.7 - Mmus\Xylb Hsap\XYLB viable FBgn0028030 l(3)S102702a lethal (3) S102702a http://flybase.org/reports/FBgn0028030 gene - - - "1027/02, l(3)S102702, l(3)S102702a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086472 RpS25 Ribosomal protein S25 http://flybase.org/reports/FBgn0086472 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "RpS25, anon-EST:Posey260, RpS31, D25, CG6684, M(3)S32, M(3)s[32], M(3)S31, M(3)86D, S25, Rp S25, Rps25" "IPR004977:Ribosomal protein S25, IPR011991:Winged helix-turn-helix DNA-binding domain" CG6684 11-Aug-17 DroID_v2017_08 Drer\rps25 "Scer\RPS25A, Scer\RPS25B" Cele\rps-25 Xtro\rps25 Mmus\Rps25 Hsap\RPS25 DRSC16837 I 1.760477892 0.057942348 0.169615307 -0.055630064 -0.185561351 0.767995142 FBgn0028105 l(3)S071501 lethal (3) S071501 http://flybase.org/reports/FBgn0028105 gene - - - "0715/01, l(3)S071501" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036936 CG14185 - http://flybase.org/reports/FBgn0036936 protein_coding_gene - - - "CT33794, CG14185" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG14185 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-267j14.7, Drer\cep97, Drer\drc3, Drer\lrrc6, Drer\lrrcc1, Drer\si:ch211-103e16.5, Drer\lrrc9, Drer\lrrc23, Drer\lrrc61, Drer\ppp1r7, Drer\lrriq1, Drer\lrguk" "Scer\NUD1, Scer\SDS22" - "Xtro\cep97, Xtro\lrrc49, Xtro\lrrc23, Xtro\dnal1, Xtro\lrrc6, Xtro\drc3, Xtro\ppp1r7, Xtro\lrrc9, Xtro\lrrcc1, Xtro\lrrc56" "Mmus\Lrguk, Mmus\Ppp1r7, Mmus\Lrrc61, Mmus\Lrrc48, Mmus\Lrrc49, Mmus\Lrrc56, Mmus\Lrrc46, Mmus\Lrrc9, Mmus\Lrriq1, Mmus\Dnal1, Mmus\Lrrcc1, Mmus\Lrrc43, Mmus\Lrrc23, Mmus\Cep97, Mmus\Lrriq3, Mmus\Lrrc6" "Hsap\LRRCC1, Hsap\LRRIQ3, Hsap\PPP1R7, Hsap\LRRC43, Hsap\DNAL1, Hsap\LRRC56, Hsap\DRC3, Hsap\CEP97, Hsap\LRRC61, Hsap\LRRIQ1, Hsap\LRRC6, Hsap\LRRC46, Hsap\LRGUK, Hsap\LRRC49, Hsap\LRRC23" "viable,visible" mesothoracic tergum FBgn0014262 l(2)X lethal (2) X http://flybase.org/reports/FBgn0014262 - gene - - - l(2)X - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001252 im interrupted margin http://flybase.org/reports/FBgn0001252 - gene - - - im - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female sterile,viable,male,reduced" "wing vein,costal vein,eye,macrochaeta,wing" FBgn0024229 hnc13 hnc13 http://flybase.org/reports/FBgn0024229 FBgn0026237 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "h-NC13, hnc13" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027171 l(2)B2 lethal (2) B2 http://flybase.org/reports/FBgn0027171 - gene - - - l(2)B2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027185 l(2)60A-H lethal (2) 60A-H http://flybase.org/reports/FBgn0027185 - gene - - - l(2)60A-H - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086659 snoRNA:Psi18S-176 snoRNA:Psi18S-176 http://flybase.org/reports/FBgn0086659 snoRNA_gene - - - "psi18s-176, snoRNA:314, Dm-314, CR33913, Psi 18S-176(SnoR314), snoRNA:Psi18S-176" - CR33913 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060741 l(3)S066610b lethal (3) S066610b http://flybase.org/reports/FBgn0060741 gene - - - "0666/10, l(3)S066610b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0017430 Nelf-E Negative elongation factor E http://flybase.org/reports/FBgn0017430 - protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter during mitosis ; GO:0007070 | inferred from direct assay negative regulation of transcription elongation from RNA polymerase II promoter ; GO:0034244 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from direct assay negative regulation of DNA-templated transcription, elongation ; GO:0032785 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype" NELF complex ; GO:0032021 | inferred from physical interaction with TH1 nucleus ; GO:0005634 | inferred from direct assay transcriptional repressor complex ; GO:0017053 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from physical interaction with UniProtKB:Q24134 "NELF, NELF-E, CG5994, anon-66Da, cg5994, Nelf-E, dNelf-E, Nelf-e, NelfE" "IPR000504:RNA recognition motif domain, IPR034637:Negative elongation factor E, RNA recognition motif, IPR033102:Negative elongation factor E" CG5994 11-Aug-17 DroID_v2017_08 Drer\nelfe - - Xtro\nelfe Mmus\Nelfe "Hsap\RBFOX1, Hsap\NELFE" pupal stage&&adult stage "visible,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,germline clone,maternal effect" "wing,adult thorax,adult head,ommatidium,second segment of antenna,third segment of antenna,arista,tarsal segment,embryonic/larval hemocyte | third instar larval stage,ganglion mother cell,trichogen cell" FBgn0036828 CG6841 - http://flybase.org/reports/FBgn0036828 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:15860 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000259 inferred from sequence or structural similarity with protein_id:BAA37140 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000259 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with protein_id:BAA37140 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "Prp6, BcDNA:LD43276, CG6841" "IPR003107:HAT (Half-A-TPR) repeat, IPR010491:PRP1 splicing factor, N-terminal, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR027108:Pre-mRNA-processing factor 6/Prp1/STA1, IPR019734:Tetratricopeptide repeat" CG6841 11-Aug-17 DroID_v2017_08 Drer\prpf6 "Scer\UTP6, Scer\PRP6" Cele\prp-6 Xtro\prpf6 Mmus\Prpf6 Hsap\PRPF6 "lethal,neuroanatomy defective,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,antenna,tarsal segment,unguis,pulvillus" DRSC21773 IE 0.391715312 2.018223583 1.4341235 2.519244203 -0.377498115 -1.230411843 FBgn0051288 CG31288 - http://flybase.org/reports/FBgn0051288 protein_coding_gene - - - "CG13665, CG31288" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31288 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.10, Cele\nhr-246, Cele\C29F7.2, Cele\H06H21.8, Cele\F20D6.5, Cele\F59B1.8, Cele\C29F7.1" - - - viable FBgn0283432 CG46275 - http://flybase.org/reports/FBgn0283432 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 "CG46275, SdicA" "IPR001680:WD40 repeat, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG46275 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267740 CR46071 - http://flybase.org/reports/FBgn0267740 non_protein_coding_gene - - - "CR46071, Mgn635" - CR46071 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040392 CG14050 - http://flybase.org/reports/FBgn0040392 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 - - "H48C10.1, EG:BACH48C10.1, CG14050" "IPR003656:Zinc finger, BED-type" CG14050 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043074 HF-BXC Homing Fragment http://flybase.org/reports/FBgn0043074 region - - - HF-BXC - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030259 CG1545 - http://flybase.org/reports/FBgn0030259 protein_coding_gene - - - "anon-EST:Posey256, BcDNA:GH01560, CG1545" - CG1545 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260967 CG42590 - http://flybase.org/reports/FBgn0260967 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42590 - CG42590 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043365 EP2146a EP2146a http://flybase.org/reports/FBgn0043365 gene - - - "EP(2)2146, EP2146a" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "scutellar bristle,tormogen cell,trichogen cell,ectopic,embryonic/larval salivary gland" FBgn0005376 x6 x6 http://flybase.org/reports/FBgn0005376 - gene - - - x6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260101 2L0128 - http://flybase.org/reports/FBgn0260101 gene - - - 2L0128 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval dorsal trunk,somatic clone" FBgn0051963 tRNA:Trp-CCA-2-1 transfer RNA:Tryptophan-CCA 2-1 http://flybase.org/reports/FBgn0051963 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "AE002638.trna1-TrpCCA, tRNA:W:CCA:AE002638, CR31963, chr2L.trna34-TrpCCA, tRNA-Trp-CCA-2-1, tRNA:Trp-CCA-2-1, tRNA:CR31963, UGG" - CR31963 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035412 CG14957 - http://flybase.org/reports/FBgn0035412 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14957 IPR002557:Chitin binding domain CG14957 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023126 anon-10Acc anon-10Acc http://flybase.org/reports/FBgn0023126 - gene - - - "22, anon-10Acc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003376 Sgs6 Salivary gland secretion 6 http://flybase.org/reports/FBgn0003376 - gene - - - "sgs6, Sgs, Sgs-6, SGS-6, Sgs6" - - 11-Aug-17 DroID_v2017_08 - - - - - - larval stage | late third instar larval stage embryonic/larval salivary gland

FBgn0016778 anon-77Bb anon-77Bb http://flybase.org/reports/FBgn0016778 - gene - - - "C, anon-77Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040815 CG14114 - http://flybase.org/reports/FBgn0040815 protein_coding_gene - - - CG14114 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085222 CG34193 - http://flybase.org/reports/FBgn0085222 protein_coding_gene - - - CG34193 - CG34193 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037911 CG10898 - http://flybase.org/reports/FBgn0037911 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797, InterPro:IPR020084" - - "anon-WO0118547.280, CG10898" "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like, IPR020084:NUDIX hydrolase, conserved site, IPR020476:NUDIX hydrolase" CG10898 11-Aug-17 DroID_v2017_08 "Drer\nudt6, Drer\nudt18" Scer\NPY1 Cele\ndx-1 Xtro\nudt18 Mmus\Nudt18 "Hsap\NUDT18, Hsap\NUDT6" "viable,fertile" FBgn0065448 l(2)SH1405 lethal (2) SH1405 http://flybase.net/reports/FBgn0065448.html gene l(2)SH2 1405 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0065391 l(2)SH1627 lethal (2) SH1627 http://flybase.org/reports/FBgn0065391 gene - - - "l(2)SH1627, l(2)SH2 1627" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026211 l(4)102CDh lethal (4) 102CDh http://flybase.org/reports/FBgn0026211 - gene - - - "10, l(4)10, 102CDh, l(4)102CDh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005682 rdgD retinal degeneration D http://flybase.org/reports/FBgn0005682 - gene - - - rdgD - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,ommatidium,eye photoreceptor cell,retina" FBgn0267650 pre-mod(mdg4)-AA - http://flybase.org/reports/FBgn0267650 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-AA, CG45988" "IPR007588:Zinc finger, FLYWCH-type" CG45988 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053405 5SrRNA:CR33405 5SrRNA:CR33405 http://flybase.org/reports/FBgn0053405 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33405, 5SrRNA:CR33405" - CR33405 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0277424 l(3)psg21 - http://flybase.org/reports/FBgn0277424 gene - - - "l(3)psg21, psg21" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005382 ggy groggy http://flybase.org/reports/FBgn0005382 - gene - - - ggy - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,temperature conditional,neurophysiology defective" FBgn0014120 anon-96Fe anon-96Fe http://flybase.org/reports/FBgn0014120 - gene - - - anon-96Fe - - 11-Aug-17 DroID_v2017_08 - - - - - - larval stage eye-antennal disc

FBgn0031037 CG14207 - http://flybase.org/reports/FBgn0031037 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model protein refolding ; GO:0042026 | inferred from direct assay chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model Z disc ; GO:0030018 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay Z disc ; GO:0030018 | colocalizes_with inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "Dmel21.3, CG14207, dHspB8, HspB8, Hsp20-like protein" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG14207 11-Aug-17 DroID_v2017_08 "Drer\hspb2, Drer\cryabb, Drer\cryaa, Drer\hspb8, Drer\hspb15, Drer\hspb7, Drer\hspb1, Drer\si:dkey-1k23.3, Drer\cryaba, Drer\hspb3, Drer\hspb9, Drer\hspb12, Drer\hspb11, Drer\hspb6" - "Cele\hsp-16.2, Cele\hsp-17, Cele\hsp-12.6, Cele\hsp-12.2, Cele\hsp-25" "Xtro\hsp30d, Xtro\hspb1, Xtro\uqcrh, Xtro\cryaa, Xtro\hspb8, Xtro\cryab, Xtro\hspb3, Xtro\hspb6, Xtro\hspb2" "Mmus\Cryab, Mmus\Hspb8, Mmus\Hspb9, Mmus\Hspb2, Mmus\Hspb6, Mmus\Hspb1, Mmus\Hspb7, Mmus\Hspb3, Mmus\Cryaa" "Hsap\CRYAB, Hsap\HSPB7, Hsap\HSPB1, Hsap\HSPB2, Hsap\CRYAA, Hsap\HSPB6, Hsap\HSPB8, Hsap\LOC102724652, Hsap\HSPB3, Hsap\HSPB9" "viable,lethal" FBgn0042201 Nplp3 Neuropeptide-like precursor 3 http://flybase.org/reports/FBgn0042201 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | non-traceable author statement neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement extracellular region ; GO:0005576 | non-traceable author statement "NPLP3, CG13061, CG18502, BcDNA:RH16169, Nplp3, nplp3, SHA, VVIamide" - CG13061 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC09944 I -0.938751205 1.582575417 0.183768495 0.563328418 -0.031505594 -0.422396686 FBgn0010093 Su(vg)E6 Suppressor of vestigial E6 http://flybase.org/reports/FBgn0010093 - gene - - - "vg[[EMS6]], Su(vg)E6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052582 CR32582 - http://flybase.org/reports/FBgn0052582 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32582, BcDNA:SD27303, CR32582, mdcds_55373" - CR32582 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0037680 pasi2 pasiflora 2 http://flybase.org/reports/FBgn0037680 protein_coding_gene - "establishment of endothelial barrier ; GO:0061028 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from direct assay "dmCG8121, pasi2, CG8121" - CG8121 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052100 CG32100 - http://flybase.org/reports/FBgn0052100 protein_coding_gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - "CG18638, CG10429, CG32100" - CG32100 11-Aug-17 DroID_v2017_08 - - - - - - "gravitaxis defective,viable" FBgn0265841 CR44630 - http://flybase.org/reports/FBgn0265841 non_protein_coding_gene - - - CR44630 - CR44630 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085822 CR41613 - http://flybase.org/reports/FBgn0085822 rRNA_gene - - - CR41613 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029133 REG REG http://flybase.org/reports/FBgn0029133 protein_coding_gene endopeptidase activator activity ; GO:0061133 | inferred from direct assay endopeptidase inhibitor activity ; GO:0004866 | inferred from direct assay "regulation of proteasomal protein catabolic process ; GO:0061136 | inferred from direct assay regulation of G1/S transition of mitotic cell cycle ; GO:2000045 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" "proteasome activator complex ; GO:0008537 | inferred from electronic annotation with InterPro:IPR003185, InterPro:IPR003186, InterPro:IPR009077 nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay cytoplasm ; GO:0005737 | colocalizes_with inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleolus ; GO:0005730 | NOT inferred from direct assay proteasome complex ; GO:0000502 | inferred from biological aspect of ancestor with PANTHER:PTN000069920" "dREG, CG1591, REG, dReggamma, dREGgamma, REGgamma, DmREGgamma, dReg" "IPR003185:Proteasome activator pa28, N-terminal domain, IPR003186:Proteasome activator pa28, C-terminal domain, IPR009077:Proteasome activator pa28" CG1591 11-Aug-17 DroID_v2017_08 "Drer\psme2, Drer\psme3, Drer\psme1" - Cele\Y66D12A.9 "Xtro\psme2, Xtro\psme3, Xtro\psme1" "Mmus\Psme2, Mmus\Psme1, Mmus\Psme2b, Mmus\Psme3, Mmus\Aoc3" "Hsap\PSME1, Hsap\PSME3, Hsap\PSME2" "viable,fertile" FBgn0020265 oap ombre-a-paupieres http://flybase.org/reports/FBgn0020265 - gene - - - oap - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065338 l(2)SH1844 lethal (2) SH1844 http://flybase.org/reports/FBgn0065338 gene - - - "l(2)SH1844, l(2)SH2 1844" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003363 sesF stress-sensitive F http://flybase.org/reports/FBgn0003363 - gene - - - sesF - - 11-Aug-17 DroID_v2017_08 - - - - - - uncoordinated FBgn0061473 34-20 34-20 http://flybase.org/reports/FBgn0061473 gene - - - 34-20 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022381 Pt-10 Larval protein-10 http://flybase.org/reports/FBgn0022381 - gene - - - Pt-10 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265814 CR44603 - http://flybase.org/reports/FBgn0265814 non_protein_coding_gene - - - "lincRNA.10, CR44603" - CR44603 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067359 l(2)NC85 lethal (2) NC85 http://flybase.org/reports/FBgn0067359 gene - - - "NC85, l(2)NC85" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267287 CR45723 - http://flybase.org/reports/FBgn0267287 non_protein_coding_gene - - - CR45723 - CR45723 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002787 Rpn8 Regulatory particle non-ATPase 8 http://flybase.org/reports/FBgn0002787 FBgn0022065 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype "proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9565 inferred from direct assay dendrite ; GO:0030425 | inferred from mutant phenotype proteasome complex ; GO:0000502 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000005787 proteasome regulatory particle ; GO:0005838 | inferred from direct assay" "RPN8, CG3416, p39B, PRSC_DROME, l(2)k08003, Rpn8, Mov34, S12, P26270, PSMD7" "IPR024969:Rpn11/EIF3F, C-terminal, IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR033858:26S Proteasome non-ATPase regulatory subunit 7/8" CG3416 11-Aug-17 DroID_v2017_08 Drer\psmd7 Scer\RPN8 Cele\rpn-8 Xtro\psmd7 Mmus\Psmd7 Hsap\PSMD7 adult stage "lethal,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,somatic clone,decreased cell number" "embryonic/larval hemocyte | third instar larval stage,wing,embryonic/larval neuroblast,ganglion mother cell,dendritic arborizing neuron,mushroom body gamma-lobe,somatic clone,neuroblast,adult mushroom body" DRSC04624 IEK -4.600104022 -3.331259077 -6.09037063 -2.616607701 1.433271406 -1.774792707 FBgn0030394 Cpr11A Cuticular protein 11A http://flybase.org/reports/FBgn0030394 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr11A, CG2560, L12" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2560 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0263413 CR43459 - http://flybase.org/reports/FBgn0263413 non_protein_coding_gene - - - "CR43459, pri-mir-277_mir-34" - CR43459 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085437 CG34408 - http://flybase.org/reports/FBgn0085437 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN001085081 regulation of small GTPase mediated signal transduction ; GO:0051056 | inferred from electronic annotation with InterPro:IPR000331 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN001085081 - "CG34408, BcDNA:GH09358, CG2967, CG32689, FBpp0111587" IPR000331:Rap GTPase activating protein domain CG34408 11-Aug-17 DroID_v2017_08 Drer\ralgapb - "Cele\hgap-2, Cele\C34C6.2" Xtro\ralgapb Mmus\Ralgapb Hsap\RALGAPB FBgn0033401 CG1968 - http://flybase.org/reports/FBgn0033401 protein_coding_gene molecular_function ; GO:0003674 | no biological data available intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000004986 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000487537 Golgi transport complex ; GO:0017119 | inferred from direct assay "Cog6, CG1968" IPR010490:Conserved oligomeric Golgi complex subunit 6 CG1968 11-Aug-17 DroID_v2017_08 Drer\cog6 Scer\COG6 Cele\cogc-6 Xtro\cog6 Mmus\Cog6 Hsap\COG6 viable FBgn0045041 l(1)G0302 lethal (1) G0302 http://flybase.org/reports/FBgn0045041 gene - - - l(1)G0302 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0010809 l(3)03675 lethal (3) 03675 http://flybase.org/reports/FBgn0010809 - gene - - - l(3)03675 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0250828 CR41437 - http://flybase.org/reports/FBgn0250828 non_protein_coding_gene - - - "CR41437, anon-EST:Posey146" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266827 CR45289 - http://flybase.org/reports/FBgn0266827 non_protein_coding_gene - - - CR45289 - CR45289 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005236 l(3)R45 lethal of Roberts 45 http://flybase.org/reports/FBgn0005236 - gene - - - "l(3)B45, l(3)R45" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0034663 CG4363 - http://flybase.org/reports/FBgn0034663 protein_coding_gene - - - "CT14230, BcDNA:LP06375, CG4363" IPR008472:Domain of unknown function DUF753 CG4363 11-Aug-17 DroID_v2017_08 - - "Cele\D1081.6, Cele\C54D10.13, Cele\ZK757.10, Cele\F55B11.4" - "Mmus\Ly6d, Mmus\Slurp2, Mmus\Lynx1, Mmus\2010109I03Rik" "Hsap\LYNX1, Hsap\LY6D" viable FBgn0061052 l(3)S023204a lethal (3) S023204a http://flybase.org/reports/FBgn0061052 gene - - - "0232/04, l(3)S023204a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0250903 lmgA lemming A http://flybase.org/reports/FBgn0250903 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from direct assay positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:14452 ubiquitin ligase complex ; GO:0000151 | inferred from direct assay anaphase-promoting complex ; GO:0005680 | inferred from direct assay "CG34440, lmgA, lmg, ORF1, CG18042, l(2)03424, Dromel_CG18042_FBtr0079695_lmg_uORF, Apc11, APC11, Img, LMG" "IPR024991:Anaphase-promoting complex subunit 11, IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG34440 11-Aug-17 DroID_v2017_08 Drer\anapc11 Scer\APC11 Cele\apc-11 Xtro\anapc11 Mmus\Anapc11 Hsap\ANAPC11 "lethal,recessive,neuroanatomy defective,somatic clone,increased cell death,mitotic cell cycle defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of prepupal stage,some die during prepupal stage,viable,fertile" "eye,histoblast,neuroblast,somatic clone,embryonic/larval brain,wing disc,intersegmental nerve,anterior fascicle & synapse" FBgn0260495 l(3)2727 - http://flybase.org/reports/FBgn0260495 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - l(3)2727 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,dendrite" FBgn0002259 l(3)68Fd lethal (3) 68Fd http://flybase.org/reports/FBgn0002259 - gene - - - "rsg21, l(3)rsg21, l(3)68Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0027778 anon-1Ab anon-1Ab http://flybase.org/reports/FBgn0027778 - gene - - - "1A, anon-1Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027795 CG14785 - http://flybase.org/reports/FBgn0027795 - protein_coding_gene - - - "EG:BACN32G11.2, CG14785" "IPR011705:BTB/Kelch-associated, IPR031750:Domain of unknown function DUF4734" CG14785 11-Aug-17 DroID_v2017_08 Drer\klhl41a - Cele\kel-3 - - "Hsap\KLHL9, Hsap\KLHL31" viable FBgn0011951 tRNA:Arg-TCG-3-4 transfer RNA:Arginine-TCG 3-4 http://flybase.org/reports/FBgn0011951 "FBgn0011947, FBgn0052617, FBgn0060079" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna7-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-e, CR32617, tRNA:arg12Ed, chrX.trna11-ArgTCG, tRNA-Arg-TCG-3-4, tRNA:Arg-TCG-3-4, tRNA:R:12Ed, CGA" - CR32617 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060343 l(3)S143814 lethal (3) S143814 http://flybase.org/reports/FBgn0060343 gene - - - "1438/14, l(3)S143814" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0060527 l(3)S101715b lethal (3) S101715b http://flybase.org/reports/FBgn0060527 gene - - - "1017/15, l(3)S101715b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005035 e(S)r "enhancer of Star, recessive" http://flybase.org/reports/FBgn0005035 - gene - - - "S-i, e(S)r, e(S)" - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0005157 l(2)G129 lethal (2) G129 http://flybase.org/reports/FBgn0005157 - gene - - - l(2)G129 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022726 milo milo http://flybase.org/reports/FBgn0022726 - gene molecular_function ; GO:0003674 | no biological data available growth ; GO:0040007 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available milo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035423 eIF1 eukaryotic translation initiation factor 1 http://flybase.org/reports/FBgn0035423 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000005188 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype formation of translation preinitiation complex ; GO:0001731 | inferred from sequence or structural similarity with SGD:S000005188 eukaryotic 43S preinitiation complex ; GO:0016282 | inferred from sequence or structural similarity with SGD:S000005188 multi-eIF complex ; GO:0043614 | inferred from sequence or structural similarity with SGD:S000005188 "anon-EST:Posey272, BcDNA:RE14985, CG17737, dEIF1, eIF1" "IPR001950:SUI1 domain, IPR005874:Eukaryotic translation initiation factor SUI1" CG17737 11-Aug-17 DroID_v2017_08 "Drer\eif1b, Drer\zgc:56676" Scer\SUI1 Cele\eif-1 "Xtro\eif1b, Xtro\eif1" "Mmus\Eif1b, Mmus\Eif1" "Hsap\EIF1B, Hsap\EIF1" viable FBgn0026204 milou milou http://flybase.org/reports/FBgn0026204 - gene - - - milou - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "wing disc,wing" FBgn0036597 CG4962 - http://flybase.org/reports/FBgn0036597 protein_coding_gene - - - "CT15908, CG4962" - CG4962 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266776 CR45241 - http://flybase.org/reports/FBgn0266776 non_protein_coding_gene - - - CR45241 - CR45241 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266471 gevuinanut - http://flybase.org/reports/FBgn0266471 gene - - - gevuinanut - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "egg chamber,somatic clone,oocyte associated follicular epithelium,follicle cell" FBgn0267163 CG45603 - http://flybase.org/reports/FBgn0267163 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45603 - CG45603 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083302 E(smoDN)1700 Enhancer of smoDN 1700 http://flybase.org/reports/FBgn0083302 gene - - - E(smoDN)1700 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035643 CG13287 - http://flybase.org/reports/FBgn0035643 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG13287 IPR013087:Zinc finger C2H2-type CG13287 11-Aug-17 DroID_v2017_08 "Drer\prdm8, Drer\si:dkeyp-41f9.4, Drer\prdm8b" - Cele\F21D5.9 Xtro\prdm8 "Mmus\Zfp488, Mmus\Prdm8" "Hsap\ZNF488, Hsap\PRDM8" lethal DRSC09961 I 0.826555674 -1.604250697 -0.786428164 0.639982357 -0.773440048 -0.076948619 FBgn0085700 CG41573 - http://flybase.org/reports/FBgn0085700 protein_coding_gene - - - CG41573 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000512 dv divergent http://flybase.org/reports/FBgn0000512 - gene - - - "aea, dv" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semi-sterile" "wing,wing vein" FBgn0065437 l(2)SH1469 lethal (2) SH1469 http://flybase.org/reports/FBgn0065437 gene - - - "l(2)SH1469, l(2)SH2 1469" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003398 shp shrimp http://flybase.org/reports/FBgn0003398 - gene - - - shp - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,reduced,male fertile,female fertile,visible,recessive" FBgn0266566 CG45105 - http://flybase.org/reports/FBgn0266566 protein_coding_gene - centrosome organization ; GO:0051297 | inferred from electronic annotation with InterPro:IPR031887 centrosome ; GO:0005813 | inferred from electronic annotation with InterPro:IPR031887 "CG45105, CG31291, CG5552, CG14878, CG34275" IPR031887:Serologically defined colon cancer antigen 8 CG45105 11-Aug-17 DroID_v2017_08 Drer\sdccag8 - - Xtro\sdccag8 Mmus\Sdccag8 Hsap\SDCCAG8 FBgn0060669 l(3)S079304b lethal (3) S079304b http://flybase.org/reports/FBgn0060669 gene - - - "0793/04, l(3)S079304b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082333 HM801 HM801 http://flybase.org/reports/FBgn0082333 gene - - - HM801 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032707 CG10348 - http://flybase.org/reports/FBgn0032707 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG10348, lincRNA.186" "IPR013087:Zinc finger C2H2-type, IPR011989:Armadillo-like helical" CG10348 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-263k4.2, Drer\mecom" "Scer\MSN2, Scer\MSN4, Scer\COM2" "Cele\odd-2, Cele\odd-1, Cele\egl-43" - "Mmus\Mecom, Mmus\Prdm16" "Hsap\PRDM16, Hsap\MECOM, Hsap\ZNF367" viable FBgn0261966 huc2L-12 hydroxyurea- and (or) caffeine-sensitive 2L-12 http://flybase.org/reports/FBgn0261966 gene - - - "huc2L-12, huc[2L-12]" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,somatic clone,lethal" "eye,somatic clone,drug conditional" FBgn0051174 CG31174 - http://flybase.org/reports/FBgn0051174 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31174, BcDNA:SD11171" IPR009991:Dynactin subunit p22 CG31174 11-Aug-17 DroID_v2017_08 Drer\dctn3 - - - Mmus\Dctn3 Hsap\DCTN3 FBgn0031457 CG3077 - http://flybase.org/reports/FBgn0031457 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3077, DmSNX21" IPR001683:Phox homologous domain CG3077 11-Aug-17 DroID_v2017_08 "Drer\snx20, Drer\snx21" - - Xtro\snx21 "Mmus\Snx20, Mmus\Snx21" "Hsap\SNX20, Hsap\SNX21" viable FBgn0041169 anon-82Aa anon-82Aa http://flybase.org/reports/FBgn0041169 gene - - - "cB151, anon-82Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | early , embryonic stage | stage 8-15 " "

ubiquitous , mesoderm

" FBgn0086171 nkd::Mmus\Nkd1 - http://flybase.org/reports/FBgn0086171 engineered_fusion_gene - - - nkd::Mmus\Nkd1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible sternite FBgn0058098 CG40098 - http://flybase.org/reports/FBgn0058098 protein_coding_gene - - - CG40098 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260019 sancho-panza sancho panza http://flybase.org/reports/FBgn0260019 gene - - - sancho-panza - - 11-Aug-17 DroID_v2017_08 - - - - - - chorion | germline clone FBgn0259321 EP-323 - http://flybase.org/reports/FBgn0259321 gene - - - EP-323 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0264979 CG4267 - http://flybase.org/reports/FBgn0264979 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG4267, CG31686, Dmel_CG4267" "IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold, IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin" CG4267 11-Aug-17 DroID_v2017_08 "Drer\LOC100331214, Drer\LOC101884800, Drer\lpl, Drer\lipg, Drer\lipca" - Cele\irld-48 "Xtro\lpl, Xtro\lipg" "Mmus\Lpl, Mmus\Lipc, Mmus\Lipg" "Hsap\PLA1A, Hsap\LIPC, Hsap\LIPG, Hsap\LPL" DRSC00102 IE -0.497545512 -2.894494065 -0.610660615 -4.632974162 -1.167931397 -0.067808142 FBgn0032726 CG10621 - http://flybase.org/reports/FBgn0032726 protein_coding_gene - - - "BEST:LD26123, anon-WO0140519.13, CG10621" IPR003726:Homocysteine-binding domain CG10621 11-Aug-17 DroID_v2017_08 Drer\zgc:172121 "Scer\SAM4, Scer\YMR321C, Scer\MHT1" "Cele\T13G4.4, Cele\metr-1" Xtro\MGC75760 "Mmus\Mtr, Mmus\Bhmt, Mmus\Bhmt2" "Hsap\MTR, Hsap\BHMT2, Hsap\BHMT" viable FBgn0030431 CG4407 - http://flybase.org/reports/FBgn0030431 protein_coding_gene FMN adenylyltransferase activity ; GO:0003919 | inferred from biological aspect of ancestor with PANTHER:PTN000591373 oxidation-reduction process ; GO:0055114 | inferred from biological aspect of ancestor with PANTHER:PTN000591370 FAD biosynthetic process ; GO:0006747 | inferred from biological aspect of ancestor with PANTHER:PTN000591373 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000591370 "CG4407, Fad1" "IPR002500:Phosphoadenosine phosphosulphate reductase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG4407 11-Aug-17 DroID_v2017_08 Drer\flad1 "Scer\MET16, Scer\FAD1, Scer\YMR178W" Cele\flad-1 - Mmus\Flad1 Hsap\FLAD1 viable FBgn0040928 CR15345 - http://flybase.org/reports/FBgn0040928 pseudogene_attribute - - - "CG15345, CR15345, BcDNA:RE52922" - CR15345 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0259410 EP-P - http://flybase.org/reports/FBgn0259410 gene - - - EP-P - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0001548 l(1)16Fb lethal (1) 16Fb http://flybase.org/reports/FBgn0001548 - gene - - - "ME-II, MEII, I[[2]], F-a, l(1)16Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,lethal,non-rescuable maternal effect,visible,recessive,body color defective,dominant,polyphasic" "gastrula embryo,wing vein,adult cuticle,macrochaeta" FBgn0027184 l(2)60A-I lethal (2) 60A-I http://flybase.org/reports/FBgn0027184 - gene - - - l(2)60A-I - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086393 BG02169 - http://flybase.org/reports/FBgn0086393 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02169 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0004762 l(3)89Cc lethal (3) 89Cc http://flybase.org/reports/FBgn0004762 - gene - - - l(3)89Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022376 Pt-15 Larval protein-15 http://flybase.org/reports/FBgn0022376 - gene - - - "PT-15, Pt-15" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040345 CG3708 - http://flybase.org/reports/FBgn0040345 protein_coding_gene - nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR002164 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR002164 "152685_at, EG:BACR7A4.18, CG3708" IPR002164:Nucleosome assembly protein (NAP) CG3708 11-Aug-17 DroID_v2017_08 "Drer\nap1l1, Drer\nap1l4b, Drer\nap1l4a" Scer\NAP1 Cele\nap-1 "Xtro\nap1l4, Xtro\nap1l1" "Mmus\Nap1l4, Mmus\Nap1l3, Mmus\Nap1l5, Mmus\Nap1l2, Mmus\Nap1l1" "Hsap\NAP1L4, Hsap\NAP1L2, Hsap\NAP1L5, Hsap\NAP1L1, Hsap\NAP1L3" viable FBgn0001431 l(1)7Aa lethal (1) 7Aa http://flybase.org/reports/FBgn0001431 - gene - - - "l(1)jnR1, jnR1, RA62, l(1)inR1, l(1)7Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038676 CG6026 - http://flybase.org/reports/FBgn0038676 protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 CG6026 - CG6026 11-Aug-17 DroID_v2017_08 - - - - Mmus\Brd4 - "lethal,viable" FBgn0002270 l(3)69Bb lethal (3) 69Bb http://flybase.org/reports/FBgn0002270 - gene - - - "rsg32, l(3)rsg32, l(3)69Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262986 CG43294 - http://flybase.org/reports/FBgn0262986 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG43294 IPR002557:Chitin binding domain CG43294 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019933 S(rux)2C S(rux)2C http://flybase.org/reports/FBgn0019933 - gene - - - S(rux)2C - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,mitotic cell cycle defective" FBgn0065434 l(2)SH1478 lethal (2) SH1478 http://flybase.org/reports/FBgn0065434 gene - - - "l(2)SH1478, l(2)SH2 1478" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039246 CG10845 - http://flybase.org/reports/FBgn0039246 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 ATPase activity ; GO:0016887 | NOT inferred from sequence or structural similarity with MGI:MGI:2447072 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with MGI:MGI:2447072 microtubule motor activity ; GO:0003777 | NOT inferred from sequence or structural similarity with MGI:MGI:2447072 biological_process ; GO:0008150 | no biological data available microtubule-based movement ; GO:0007018 | NOT inferred from sequence or structural similarity with MGI:MGI:2447072 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with Khc "CG10845, Klp96B, KIF26A/B" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001752:Kinesin motor domain" CG10845 11-Aug-17 DroID_v2017_08 "Drer\kif3b, Drer\kif5ba, Drer\kif5ab, Drer\kif5c, Drer\kif5bb, Drer\kif3a, Drer\lztfl1, Drer\kif3cb" "Scer\SMY1, Scer\KIP3" Cele\unc-116 "Xtro\kif5c, Xtro\kif3c, Xtro\lztfl1, Xtro\kif3b, Xtro\kif5b, Xtro\kif5a" "Mmus\Lztfl1, Mmus\Kif5a, Mmus\Kif3a, Mmus\Kif3c, Mmus\Kif5b, Mmus\Kif5c, Mmus\Kif3b" "Hsap\KIF5C, Hsap\KIF5A, Hsap\KIF3C, Hsap\LZTFL1, Hsap\KIF5B, Hsap\KIF3B" viable FBgn0035762 Rint1 RAD50 interactor 1 http://flybase.org/reports/FBgn0035762 protein_coding_gene - cleavage furrow ingression ; GO:0036090 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred from sequence or structural similarity with SGD:S000003113 Golgi organization ; GO:0007030 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000003113 Dsl1/NZR complex ; GO:0070939 | inferred from sequence or structural similarity with SGD:S000003113 "CG8605, Tip20, Rint-1, Rint1, rint1" IPR007528:RINT-1/Tip20 CG8605 11-Aug-17 DroID_v2017_08 Drer\rint1 Scer\TIP20 Cele\F36D1.6 Xtro\rint1 Mmus\Rint1 Hsap\RINT1 "cytokinesis defective,lethal,neuroanatomy defective,body color defective" "Golgi stackbam.THsimVP16,spermatid | third instar larval stage,Nebenkern,contractile ringbam.THsimVP16,spindlebam.THsimVP16,cleavage furrowbam.THsimVP16,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0264504 CR43903 - http://flybase.org/reports/FBgn0264504 non_protein_coding_gene - - - CR43903 - CR43903 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000763 fs(1)A543 female sterile (1) A543 http://flybase.org/reports/FBgn0000763 - gene - - - fs(1)A543 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,heat sensitive" "wing,female reproductive system" FBgn0085360 CG34331 - http://flybase.org/reports/FBgn0085360 protein_coding_gene - - - CG34331 - CG34331 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0060987 l(3)S028102b lethal (3) S028102b http://flybase.org/reports/FBgn0060987 gene - - - "0281/02, l(3)S028102b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262534 CG43088 - http://flybase.org/reports/FBgn0262534 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43088, MB8.chrX.pasa.104, MB8.chrX.pasa.104-MIP02663" IPR027806:Harbinger transposase-derived nuclease domain CG43088 11-Aug-17 DroID_v2017_08 "Drer\LOC101887042, Drer\si:dkey-121j17.6, Drer\zmp:0000000634, Drer\LOC101883368, Drer\harbi1, Drer\zgc:162945, Drer\zgc:194221, Drer\LOC569097, Drer\si:dkey-197c15.6, Drer\zgc:113227, Drer\LOC100005423, Drer\LOC103911715, Drer\LOC101882290" - - Xtro\LOC100127800 Mmus\Harbi1 Hsap\HARBI1 FBgn0051545 CG31545 - http://flybase.org/reports/FBgn0051545 protein_coding_gene - - - CG31545 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085714 CG41592 - http://flybase.org/reports/FBgn0085714 protein_coding_gene - - - CG41592 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001130 Gpt Glutamate pyruvate transaminase http://flybase.org/reports/FBgn0001130 - gene - - - "GPT, Gpt" - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0034480 CG16898 - http://flybase.org/reports/FBgn0034480 protein_coding_gene - - - CG16898 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG16898 11-Aug-17 DroID_v2017_08 - - "Cele\F59B1.8, Cele\Y11D7A.8, Cele\F58B4.5, Cele\H37A05.2, Cele\dhs-27, Cele\D1044.1, Cele\Y45G12C.4, Cele\C29F7.2, Cele\T16G1.5, Cele\F59B1.10, Cele\E02C12.9, Cele\nhr-246, Cele\F56A4.5, Cele\F49C12.7, Cele\H06H21.8, Cele\E02C12.8, Cele\E02C12.6, Cele\T16G1.6, Cele\C18B10.6, Cele\E02C12.10, Cele\C29F7.1" - - - viable FBgn0019683 mng mango http://flybase.org/reports/FBgn0019683 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available mng - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023154 Su(mg)2-5 Suppressor of modifier of gypsy 2-5 http://flybase.org/reports/FBgn0023154 - gene - - - Su(mg)2-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010557 l(2)03832a lethal (2) 03832a http://flybase.org/reports/FBgn0010557 - gene - - - "l(2)03832, l(2)03832a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021988 l(2)k09624 lethal (2) k09624 http://flybase.org/reports/FBgn0021988 - gene - - - l(2)k09624 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259330 C371 - http://flybase.org/reports/FBgn0259330 gene - - - C371 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0260381 GSd439 - http://flybase.org/reports/FBgn0260381 gene - - - GSd439 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0034547 CG12485 - http://flybase.org/reports/FBgn0034547 protein_coding_gene - - - CG12485 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044491 DTD46.6 DTD46.6 http://flybase.org/reports/FBgn0044491 gene - - - DTD46.6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265855 CR44644 - http://flybase.org/reports/FBgn0265855 non_protein_coding_gene - - - CR44644 - CR44644 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024305 SS3-6 Suppressor of GMR-sina 3-6 http://flybase.org/reports/FBgn0024305 - gene molecular_function ; GO:0003674 | no biological data available rhabdomere development ; GO:0042052 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available SS3-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "rhabdomere,somatic clone" FBgn0265638 CR44445 - http://flybase.org/reports/FBgn0265638 non_protein_coding_gene - - - "CR44445, lincRNA.264" - CR44445 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029907 Atx-1 Ataxin 1 http://flybase.org/reports/FBgn0029907 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR003652, InterPro:IPR013723" imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype - "dAtx-1, CG4547, Atx-1" "IPR003652:Ataxin, AXH domain" CG4547 11-Aug-17 DroID_v2017_08 "Drer\atxn1l, Drer\atxn1a, Drer\LOC101886356, Drer\zmp:0000000926, Drer\atxn1b" - Cele\K04F10.1 "Xtro\atxn1, Xtro\atxn1l" "Mmus\Atxn1l, Mmus\Atxn1" "Hsap\ATXN1, Hsap\ATXN1L" "viable,fertile,neuroanatomy defective" "eye,eye photoreceptor cell,wing vein,ectopic,interommatidial bristle,ommatidium,rhabdomere of eye photoreceptor cell,heat sensitive,wing,wing margin bristle,metathoracic bristle,mesothoracic bristle" FBgn0267179 CR45619 - http://flybase.org/reports/FBgn0267179 non_protein_coding_gene - - - CR45619 - CR45619 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021949 l(2)k10411 lethal (2) k10411 http://flybase.org/reports/FBgn0021949 - gene - - - l(2)k10411 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001367 l(1)1Ff lethal (1) 1Ff http://flybase.org/reports/FBgn0001367 - gene - - - l(1)1Ff - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,rescuable maternal effect" FBgn0033934 CG17385 - http://flybase.org/reports/FBgn0033934 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG17385, CC7" IPR013087:Zinc finger C2H2-type CG17385 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-253d23.2, Drer\znf1157, Drer\zgc:113372, Drer\zgc:171422, Drer\zgc:173693, Drer\si:dkey-15h8.16, Drer\LOC100535506, Drer\zgc:100951, Drer\znf1184, Drer\zgc:110821, Drer\si:dkeyp-2e4.8, Drer\si:dkey-1b17.5, Drer\si:ch211-161m3.4, Drer\si:dkey-1b17.8, Drer\znf1154, Drer\si:ch211-241e1.5, Drer\znf990, Drer\znf1169, Drer\znf1002, Drer\zgc:113886, Drer\zgc:66483, Drer\znf1161, Drer\znf1003, Drer\zgc:174623, Drer\znf1173, Drer\zgc:113030, Drer\zgc:113452" "Scer\AZF1, Scer\ZAP1" "Cele\ZK686.5, Cele\che-1, Cele\ztf-23, Cele\fezf-1, Cele\let-391, Cele\Y55F3AM.14" - "Mmus\5730507C01Rik, Mmus\Zfp985, Mmus\Zfp936" "Hsap\ZNF383, Hsap\ZNF286B, Hsap\ZNF454, Hsap\ZNF502, Hsap\ZNF883" "viable,visible" trichogen cell DRSC06664 EK 1.278973039 0.940801573 3.593102745 0.056067651 -0.369641076 1.562939491 FBgn0036121 CG6310 - http://flybase.org/reports/FBgn0036121 protein_coding_gene - - - "BcDNA:AT03632, CG6310" IPR023393:START-like domain CG6310 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028588 l(?)AP17 lethal (?) AP17 http://flybase.org/reports/FBgn0028588 gene - - - l(?)AP17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069936 CG41113 - http://flybase.org/reports/FBgn0069936 protein_coding_gene - - - CG41113 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011613 l(1)I33e30 lethal (1) I33e30 http://flybase.org/reports/FBgn0011613 FBgn0010206 gene - - - "l(1)33e30, l(1)I33e30" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262567 CG43107 - http://flybase.org/reports/FBgn0262567 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43107, MIP12466, lincRNA.331" - CG43107 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033134 Tsp42El Tetraspanin 42El http://flybase.org/reports/FBgn0033134 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sleep ; GO:0030431 | inferred from expression pattern cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model "CG12840, Dm.Tsp42El, anon-EST:Posey244, Tsp42El, Tsp42E1" "IPR018499:Tetraspanin/Peripherin, IPR008952:Tetraspanin, EC2 domain, IPR000301:Tetraspanin" CG12840 11-Aug-17 DroID_v2017_08 "Drer\cd63, Drer\tspan4a" - "Cele\tsp-3, Cele\tsp-2, Cele\tsp-7, Cele\tsp-1, Cele\tsp-14" Xtro\tspan3 Mmus\Cd63 Hsap\CD63 viable FBgn0002309 l(3)84Fg lethal (3) 84Fg http://flybase.org/reports/FBgn0002309 - gene - - - "l(3)EfH2, l(3)84Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034361 mRpS28 mitochondrial ribosomal protein S28 http://flybase.org/reports/FBgn0034361 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82673 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82673 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82673 "MRP-S35, CG5497, BcDNA:RH13070, mRpS28, mrpS28" "IPR019375:Ribosomal protein S28, mitochondrial" CG5497 11-Aug-17 DroID_v2017_08 Drer\mrps28 - Cele\mrps-28 "Xtro\mrps28, Xtro\tpd52" Mmus\Mrps28 Hsap\MRPS28 "viable,visible" trichogen cell FBgn0261865 lgr lounger http://flybase.org/reports/FBgn0261865 gene - larval foraging behavior ; GO:0035177 | inferred from mutant phenotype - lgr - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002084 l(2)49Fm lethal (2) 49Fm http://flybase.org/reports/FBgn0002084 - gene - - - "vr-18, l(2)vr18, l(2)49Fm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,non-suppressor of variegation,dominant" FBgn0002432 l(3)KE90 lethal (3) KE90 http://flybase.org/reports/FBgn0002432 - gene - - - l(3)KE90 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034703 CG3045 - http://flybase.org/reports/FBgn0034703 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001406, InterPro:IPR020094, InterPro:IPR020095, InterPro:IPR020097, InterPro:IPR020103 pseudouridine synthase activity ; GO:0009982 | inferred from biological aspect of ancestor with PANTHER:PTN000124732" mRNA pseudouridine synthesis ; GO:1990481 | inferred from biological aspect of ancestor with PANTHER:PTN000124846 tRNA pseudouridine synthesis ; GO:0031119 | inferred from biological aspect of ancestor with PANTHER:PTN000124732 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000124846 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000124846 CG3045 "IPR001406:Pseudouridine synthase I, TruA, IPR020095:Pseudouridine synthase I, TruA, C-terminal, IPR020097:Pseudouridine synthase I, TruA, alpha/beta domain, IPR020103:Pseudouridine synthase, catalytic domain" CG3045 11-Aug-17 DroID_v2017_08 "Drer\pus3, Drer\pusl1" "Scer\DEG1, Scer\PUS1" Cele\tag-124 Xtro\pus3 "Mmus\Pusl1, Mmus\Pus3" "Hsap\PUSL1, Hsap\PUS3" viable FBgn0052436 CG32436 - http://flybase.org/reports/FBgn0052436 protein_coding_gene - - - "CG6968, CG12973, CG32436, HD35012" - CG32436 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" "trichogen cell,supernumerary" FBgn0027164 l(2)KC-B l(2)Karp and Cherbas B http://flybase.org/reports/FBgn0027164 - gene - - - "B, l(2)KC-B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085778 CR40962 - http://flybase.org/reports/FBgn0085778 rRNA_gene - - - CR40962 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003239 Rex Ribosomal exchange http://flybase.org/reports/FBgn0003239 - gene - - - "Su(Rex), Rex" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,maternal effect,semidominant" FBgn0262067 EG7 - http://flybase.org/reports/FBgn0262067 gene - - - EG7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023040 l(2)46Ec lethal (2) 46Ec http://flybase.org/reports/FBgn0023040 FBgn0019725 gene - - - "G, 5.2, l(2)46CFc, l(2)46Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0021991 l(2)k09613 lethal (2) k09613 http://flybase.org/reports/FBgn0021991 - gene - - - l(2)k09613 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026348 Su(da[lyh])26E2 Su(da[lyh])26E2 http://flybase.org/reports/FBgn0026348 - gene - - - "Su(da[lyh]), Su(da[lyh])26E2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267418 CR45771 - http://flybase.org/reports/FBgn0267418 pseudogene_attribute - - - "CR45771, Mst77Y" - CR45771 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262476 CG43066 - http://flybase.org/reports/FBgn0262476 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT neurotransmitter transport ; GO:0006836 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 plasma membrane ; GO:0005886 | inferred from direct assay "CG43066, anon-WO0149848.1, CG5226, CG42510" IPR000175:Sodium:neurotransmitter symporter CG43066 11-Aug-17 DroID_v2017_08 "Drer\slc6a19a.1, Drer\slc6a1l, Drer\slc6a1b, Drer\slc6a5, Drer\slc6a13l, Drer\slc6a2, Drer\si:ch211-132b12.1, Drer\slc6a6a, Drer\si:ch211-132b12.6, Drer\slc6a4b, Drer\slc6a14, Drer\slc6a13, Drer\slc6a1a, Drer\slc6a6b, Drer\slc6a19b, Drer\slc6a4a, Drer\slc6a18, Drer\slc6a16a, Drer\zgc:158225, Drer\si:ch211-117c9.5, Drer\slc6a19a.2, Drer\slc6a11a, Drer\slc6a16b, Drer\slc6a17, Drer\si:ch211-132b12.2, Drer\slc6a15, Drer\slc6a13, Drer\slc6a9, Drer\slc6a8" - "Cele\mod-5, Cele\dat-1, Cele\snf-11, Cele\snf-6, Cele\snf-3" "Xtro\slc6a3, Xtro\slc6a12, Xtro\slc6a7, Xtro\slc6a13, Xtro\LOC100127682, Xtro\slc6a19, Xtro\slc6a15, Xtro\slc6a9, Xtro\slc6a14.2, Xtro\slc6a5, Xtro\slc6a17, Xtro\slc6a4, Xtro\slc6a16, Xtro\slc6a6, Xtro\slc6a8, Xtro\slc6a1, Xtro\slc6a2" "Mmus\Slc6a16, Mmus\Slc6a15, Mmus\Slc6a5, Mmus\Slc6a18, Mmus\Slc6a20b, Mmus\Slc6a21, Mmus\Slc6a4, Mmus\Slc6a8, Mmus\Slc6a2, Mmus\Slc6a14, Mmus\Slc6a9, Mmus\Slc6a7, Mmus\Slc6a1, Mmus\Slc6a6, Mmus\Slc6a3, Mmus\Slc6a12, Mmus\Slc6a19, Mmus\Slc6a13, Mmus\Slc6a11, Mmus\Slc6a17, Mmus\Slc6a20a" "Hsap\SLC6A19, Hsap\SLC6A4, Hsap\SLC6A5, Hsap\SLC6A14, Hsap\SLC6A12, Hsap\SLC6A1, Hsap\SLC6A20, Hsap\SLC6A11, Hsap\SLC6A6, Hsap\SLC6A13, Hsap\SLC6A8, Hsap\SLC6A9, Hsap\SLC6A18, Hsap\SLC6A16, Hsap\SLC6A15, Hsap\SLC6A2, Hsap\SLC6A17, Hsap\SLC6A7, Hsap\SLC6A3" FBgn0037535 PIG-H Phosphatidylinositol glycan anchor biosynthesis class H http://flybase.org/reports/FBgn0037535 protein_coding_gene - GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000391179 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506 | inferred from biological aspect of ancestor with PANTHER:PTN000391179 "PIG-H, CG14463" - CG14463 11-Aug-17 DroID_v2017_08 Drer\pigh Scer\GPI15 - - Mmus\Pigh Hsap\PIGH "viable,fertile" FBgn0053417 5SrRNA:CR33417 5SrRNA:CR33417 http://flybase.org/reports/FBgn0053417 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33417, 5SrRNA:CR33417" - CR33417 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013667 ms(3)neo117 ms(3)neo117 http://flybase.org/reports/FBgn0013667 - gene - - - ms(3)neo117 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0025153 ms(2)A3 ms(2)A3 http://flybase.org/reports/FBgn0025153 - gene - - - ms(2)A3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0016879 l(2)39DEd lethal (2) 39DEd http://flybase.org/reports/FBgn0016879 - gene - - - "H173, l(2)39DEd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0083303 E(smoDN)1644 Enhancer of smoDN 1644 http://flybase.org/reports/FBgn0083303 gene - - - E(smoDN)1644 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002709 mei-218 meiotic 218 http://flybase.org/reports/FBgn0002709 "FBgn0053067, FBtr0089819, FBpp0088760, FBtr0089820, FBpp0088761, FBtr0089821, FBpp0088762" protein_coding_gene - reciprocal meiotic recombination ; GO:0007131 | traceable author statement reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG8923, CG33067, mei-218" - CG8923 11-Aug-17 DroID_v2017_08 "Drer\mcmdc2, Drer\mcm4" Scer\MCM4 Cele\mcm-4 - "Mmus\Mcm4, Mmus\Mcmdc2" "Hsap\MCMDC2, Hsap\MCM4" "viable,meiotic cell cycle defective,female,fertile,female fertile,male fertile,wild-type,female semi-sterile,DNA repair defective" "cell cycle,oocyte,meiosis & nuclear chromosome | female" FBgn0036512 CG16979 - http://flybase.org/reports/FBgn0036512 protein_coding_gene thiolester hydrolase activity ; GO:0016790 | inferred from sequence or structural similarity with UniProtKB:Q9NUQ7 UFM1 hydrolase activity ; GO:0071567 | inferred from sequence or structural similarity with UniProtKB:Q9NUQ7 UFM1 hydrolase activity ; GO:0071567 | inferred from biological aspect of ancestor with PANTHER:PTN000325444 sleep ; GO:0030431 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence or structural similarity with UniProtKB:Q9NUQ7 endomembrane system ; GO:0012505 | inferred from direct assay CG16979 "IPR012462:Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2" CG16979 11-Aug-17 DroID_v2017_08 "Drer\ufsp1, Drer\ufsp2" - Cele\odr-8 Xtro\ufsp2 "Mmus\Ufsp1, Mmus\Ufsp2" "Hsap\UFSP2, Hsap\UFSP1" FBgn0002246 l(3)68Ch lethal (3) 68Ch http://flybase.org/reports/FBgn0002246 - gene - - - "rsg7, l(3)rsg7, l(3)68Ch" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011192 l(1)296-22 lethal (1) 296-22 http://flybase.org/reports/FBgn0011192 FBgn0010201 gene - - - "296-22, l(1)296-22" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034463 CG15125 - http://flybase.org/reports/FBgn0034463 protein_coding_gene - - - CG15125 - CG15125 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034566 CG9313 - http://flybase.org/reports/FBgn0034566 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of sound ; GO:0007605 | inferred from mutant phenotype cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:Q9UI46 outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q9UI46 CG9313 "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG9313 11-Aug-17 DroID_v2017_08 "Drer\dnai1.1, Drer\wdr34, Drer\dnai1.2" - Cele\prp-17 Xtro\wdr34 "Mmus\Wdr34, Mmus\Dnaic1" "Hsap\DNAI1, Hsap\WDR34" "auditory perception defective,neurophysiology defective,viable" FBgn0011410 l(3)j8B9 lethal (3) j8B9 http://flybase.org/reports/FBgn0011410 - gene - - - l(3)j8B9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025723 A122 A122 http://flybase.org/reports/FBgn0025723 - gene molecular_function ; GO:0003674 | no biological data available Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N sensory organ development ; GO:0007423 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available A122 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005437 l(1)v59 lethal (1) v59 http://flybase.org/reports/FBgn0005437 - gene - - - "l(1)59, l(1)v59" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266684 CR45174 - http://flybase.org/reports/FBgn0266684 non_protein_coding_gene - - - CR45174 - CR45174 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038397 CG10185 - http://flybase.org/reports/FBgn0038397 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10185 "IPR001680:WD40 repeat, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR025139:Domain of unknown function DUF4062" CG10185 11-Aug-17 DroID_v2017_08 "Drer\nwd2, Drer\LOC101885341, Drer\nwd1, Drer\wdr18" Scer\IPI3 Cele\T05C3.2 Xtro\nwd2 "Mmus\Nwd1, Mmus\Wdr18, Mmus\Nwd2" "Hsap\WDR18, Hsap\NWD1, Hsap\NWD2" viable FBgn0023090 dtr defective transmitter release http://flybase.org/reports/FBgn0023090 FBgn0051623 protein_coding_gene dynein complex binding ; GO:0070840 | inferred from sequence or structural similarity with UniProtKB:Q7ZV84 motile cilium assembly ; GO:0044458 | inferred from electronic annotation with InterPro:IPR027734 chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with UniProtKB:Q7ZV84 axoneme ; GO:0005930 | inferred from sequence or structural similarity with UniProtKB:Q8NEP3 "CG31623, dtr, Dtr" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR027734:Dynein assembly factor 1, axonemal" CG31623 11-Aug-17 DroID_v2017_08 "Drer\tlr2, Drer\dnaaf1, Drer\tlr21, Drer\ppp1r42, Drer\tlr19" "Scer\SDS22, Scer\NUD1" Cele\gip-2 Xtro\ppp1r42 "Mmus\Ppp1r42, Mmus\Tlr2, Mmus\Dnaaf1" "Hsap\DNAAF1, Hsap\LRRCC1, Hsap\PPP1R42, Hsap\TLR2" "visual behavior defective,neurophysiology defective,viable" FBgn0004782 Ccp84Ab Ccp84Ab http://flybase.org/reports/FBgn0004782 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "cc7, CG1252, BG:DS00004.2, Ccp84Ab, Ccp, DmelCcp84Ab" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG1252 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - DRSC25096 K -0.100466093 -0.552837273 0.440149193 0.290791865 -1.529617353 -0.238832858 FBgn0261830 CG42762 - http://flybase.org/reports/FBgn0261830 protein_coding_gene - - - CG42762 - CG42762 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031969 pes peste http://flybase.org/reports/FBgn0031969 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "CG7228, Pes, pes" IPR002159:CD36 family CG7228 11-Aug-17 DroID_v2017_08 "Drer\cd36, Drer\LOC564077, Drer\scarb2, Drer\scarb1" - "Cele\scav-3, Cele\scav-6, Cele\scav-2, Cele\scav-1" "Xtro\cd36, Xtro\scarb2, Xtro\scarb1" "Mmus\Cd36, Mmus\Scarb1, Mmus\Scarb2" "Hsap\SCARB2, Hsap\CD36, Hsap\SCARB1" viable FBgn0043593 E(ro[DOM])2409 E(ro[DOM])2409 http://flybase.org/reports/FBgn0043593 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available E(ro[DOM])2409 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062650 EP393 EP393 http://flybase.org/reports/FBgn0062650 gene - - - "EP(2)0393, EP393" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069124 mir-P323-2 mir-P323-2 http://flybase.org/reports/FBgn0069124 miRNA_gene - - - mir-P323-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017359 l(3)F51 lethal (3) F51 http://flybase.org/reports/FBgn0017359 - gene - - - "l(3)51, l(3)F51" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0038198 Npc2b Niemann-Pick type C-2b http://flybase.org/reports/FBgn0038198 protein_coding_gene sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 intracellular cholesterol transport ; GO:0032367 | inferred from electronic annotation with InterPro:IPR033916 ecdysteroid biosynthetic process ; GO:0045456 | inferred from genetic interaction with Npc2a sterol transport ; GO:0015918 | inferred from genetic interaction with Npc2a multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CT10556, DmML2, Npc2b, CG3153, npc2b, NPC2" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set, IPR033916:ML domain, Npc2 like" CG3153 11-Aug-17 DroID_v2017_08 "Drer\zgc:193725, Drer\npc2" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 "viable,fertile,visible,body color defective" mesothoracic tergum FBgn0065771 l(2)SH0462 lethal (2) SH0462 http://flybase.org/reports/FBgn0065771 gene - - - "l(2)SH0462, l(2)SH2 0462" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004490 don-giovanni don giovanni http://flybase.org/reports/FBgn0004490 - gene - negative regulation of female receptivity ; GO:0007621 | traceable author statement female courtship behavior ; GO:0008050 | non-traceable author statement - "don-giovanni, dg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,male" FBgn0024607 olfJ147 olfactory J147 http://flybase.org/reports/FBgn0024607 - gene - - - olfJ147 - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0086384 Mer Merlin http://flybase.org/reports/FBgn0086384 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR008954 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with sav protein binding ; GO:0005515 | inferred from physical interaction with arm inferred from physical interaction with Moe protein binding ; GO:0005515 | inferred from physical interaction with ex "negative regulation of organ growth ; GO:0046621 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype negative regulation of glial cell proliferation ; GO:0060253 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from genetic interaction with ex regulation of compound eye retinal cell programmed cell death ; GO:0046669 | inferred from mutant phenotype meiotic chromosome separation ; GO:0051307 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from genetic interaction with ex compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from genetic interaction with ex regulation of apoptotic process ; GO:0042981 | inferred from genetic interaction with ex decapentaplegic signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp hippo signaling ; GO:0035329 | inferred from genetic interaction with ex, hpo axis specification ; GO:0009798 | inferred from mutant phenotype pole plasm mRNA localization ; GO:0019094 | inferred from mutant phenotype protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype cell cycle arrest ; GO:0007050 | inferred from genetic interaction with ex regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with crb negative regulation of organ growth ; GO:0046621 | inferred from genetic interaction with ex male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype regulation of cell differentiation ; GO:0045595 | inferred from genetic interaction with ex negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype inferred from genetic interaction with ex sperm individualization ; GO:0007291 | inferred from mutant phenotype cell-cell signaling ; GO:0007267 | inferred from expression pattern regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype regulation of cell growth ; GO:0001558 | inferred from expression pattern spermatogenesis ; GO:0007283 | inferred from mutant phenotype regulation of signal transduction ; GO:0009966 | inferred from genetic interaction with ex positive regulation of protein phosphorylation ; GO:0001934 | inferred from direct assay positive regulation of phosphorylation ; GO:0042327 | inferred from genetic interaction with ex endocytosis ; GO:0006897 | inferred from expression pattern" "extrinsic component of membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798, InterPro:IPR011174, InterPro:IPR011259 cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 cytoplasm ; GO:0005737 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay Kibra-Ex-Mer complex ; GO:0036375 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay Nebenkern ; GO:0016006 | inferred from direct assay fusome ; GO:0045169 | NOT inferred from direct assay membrane ; GO:0016020 | inferred from direct assay" "mer, Mer, BG01543, CG14228, Dmerlin, EMR2, Emr2, D-Mer, NF2" "IPR011993:PH domain-like, IPR011259:Ezrin/radixin/moesin, C-terminal, IPR011174:Ezrin/radixin/moesin, IPR008954:Moesin tail domain, IPR000798:Ezrin/radixin/moesin-like, IPR000299:FERM domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR015788:Moesin/ezrin/radixin homologue 2, IPR018979:FERM, N-terminal, IPR018980:FERM, C-terminal PH-like domain, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain" CG14228 11-Aug-17 DroID_v2017_08 "Drer\ezrb, Drer\ccdc120, Drer\si:ch211-220f12.1, Drer\nf2b, Drer\zgc:153953, Drer\msnb, Drer\msna, Drer\ezra, Drer\si:ch211-169p10.1, Drer\nf2a, Drer\si:ch211-163l21.4, Drer\frmd4bb" - "Cele\nfm-1, Cele\erm-1" "Xtro\msn, Xtro\ezr, Xtro\frmd4a, Xtro\frmd4b, Xtro\nf2, Xtro\rdx" "Mmus\Rdx, Mmus\Nf2, Mmus\Frmd4a, Mmus\5730559C18Rik, Mmus\Msn, Mmus\Ezr, Mmus\Frmd4b, Mmus\Ccdc120" "Hsap\CCDC120, Hsap\EZR, Hsap\FRMD4B, Hsap\RDX, Hsap\MSN, Hsap\C1orf106, Hsap\FRMD4A, Hsap\NF2" FBgn0005335 podK podoptera of Kellen Piternick http://flybase.org/reports/FBgn0005335 - gene - - - "pod-K, podK" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,eye,postvertical bristle" FBgn0050342 Prp38 pre-mRNA processing factor 38 http://flybase.org/reports/FBgn0050342 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Mfap1 "regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype" protein complex ; GO:0043234 | inferred from physical interaction with Mfap1 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG8054, prp38, dprp38, Prp38, CG30342" "IPR005037:Pre-mRNA-splicing factor 38, IPR024767:Pre-mRNA-splicing factor 38, C-terminal" CG30342 11-Aug-17 DroID_v2017_08 Drer\prpf38a Scer\PRP38 Cele\prp-38 Xtro\prpf38a Mmus\Prpf38a Hsap\PRPF38A "increased cell death,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,viable,lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage" "wing disc,somatic clone,wing pouch" FBgn0002499 l(3)SG60 lethal (3) SG60 http://flybase.org/reports/FBgn0002499 FBgn0004729 gene - - - "l(3)2306, l(3)ds13, l(3)B13, l(3)SG60" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0052847 CG32847 - http://flybase.org/reports/FBgn0052847 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ubiquitin-like protein conjugating enzyme binding ; GO:0044390 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10068 ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:10068 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 Derlin-1 retrotranslocation complex ; GO:0036513 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 CG32847 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG32847 11-Aug-17 DroID_v2017_08 "Drer\rnf5, Drer\rnf185" Scer\SLX8 Cele\rnf-5 "Xtro\rnf185, Xtro\rnf5" "Mmus\Rnf185, Mmus\Rnf5, Mmus\Trim26" "Hsap\RNF185, Hsap\TRIM26, Hsap\RNF5" viable DRSC22901 K 0.516893721 -1.482651924 0.562264829 -0.377019019 1.572156915 0.717834331 FBgn0069145 mcl(3)Z4085 mcl(3)Z4085 http://flybase.org/reports/FBgn0069145 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z4085 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0024869 l(2)k14209 lethal (2) k14209 http://flybase.org/reports/FBgn0024869 - gene - - - l(2)k14209 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266197 CR44892 - http://flybase.org/reports/FBgn0266197 non_protein_coding_gene - - - CR44892 - CR44892 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033891 CG8067 - http://flybase.org/reports/FBgn0033891 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR013216 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR013216 cellular_component ; GO:0005575 | no biological data available CG8067 "IPR013216:Methyltransferase type 11, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG8067 11-Aug-17 DroID_v2017_08 Drer\ndufaf5 - Cele\K09E4.3 Xtro\ndufaf5 Mmus\Ndufaf5 Hsap\NDUFAF5 viable FBgn0263126 Ubx::Csal\abd-A - http://flybase.org/reports/FBgn0263126 engineered_fusion_gene - - - "Ubx::Zzzz\Cs-abd-A, Ubx::Csal\abd-A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050284 CG30284 - http://flybase.org/reports/FBgn0050284 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs16b04, BcDNA:AT12437, BcDNA:AT22714, CG30284" IPR031968:VASt domain CG30284 11-Aug-17 DroID_v2017_08 "Drer\gramd1c, Drer\gramd2a, Drer\gramd1ba, Drer\gramd1bb, Drer\gramd1a" "Scer\LAM4, Scer\LAM6, Scer\LAM5, Scer\YSP2" Cele\ZC328.3 "Xtro\gramd1c, Xtro\gramd1b, Xtro\gramd3" "Mmus\Gramd1a, Mmus\Gramd1b, Mmus\Gramd3, Mmus\Gramd1c, Mmus\Gramd2" "Hsap\GRAMD3, Hsap\GRAMD2, Hsap\GRAMD1A, Hsap\GRAMD1C, Hsap\GRAMD1B" viable FBgn0267290 CR45726 - http://flybase.org/reports/FBgn0267290 non_protein_coding_gene - - - CR45726 - CR45726 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053322 CG33322 - http://flybase.org/reports/FBgn0053322 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "38E.23, CG9329, BcDNA:AT04844, CG33322" - CG33322 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0001740 l(1)HM10 lethal (1) HM10 http://flybase.org/reports/FBgn0001740 - gene - - - l(1)HM10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female semi-sterile,visible,tumorigenic" "wing,adult abdomen" FBgn0037672 sage salivary gland-expressed bHLH http://flybase.org/reports/FBgn0037672 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000468430 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with tap transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from biological aspect of ancestor with PANTHER:PTN000468430" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with tap positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay salivary gland development ; GO:0007431 | inferred from mutant phenotype" polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0003700 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000468430 "Sage, CG12952, sage, bHLHc7" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG12952 11-Aug-17 DroID_v2017_08 "Drer\myf6, Drer\mespab, Drer\mespba, Drer\mespbb, Drer\mespaa, Drer\msgn1" - Cele\hlh-32 "Xtro\msgn1, Xtro\mespb, Xtro\mespa" "Mmus\Lyl1, Mmus\Msgn1, Mmus\Mesp2, Mmus\Mesp1" "Hsap\MESP2, Hsap\MESP1, Hsap\MSGN1" embryonic stage | stage >=10 adult salivary gland primordium

increased cell death embryonic/larval salivary gland FBgn0069335 UY3164 UY3164 http://flybase.org/reports/FBgn0069335 gene - - - UY3164 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell,mushroom body & axoney-OK107" FBgn0051424 Ir94b Ionotropic receptor 94b http://flybase.org/reports/FBgn0051424 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir94b, DmelIR94b, CG31424, IR94b" - CG31424 11-Aug-17 DroID_v2017_08 - - - - - - "body color defective,partially lethal - majority die,some die during pupal stage,auditory perception defective" mesothoracic tergum FBgn0002690 miniature-blistered miniature blistered http://flybase.org/reports/FBgn0002690 - gene - - - "mbs, miniature-blistered" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,poor,fertile" "wing,macrochaeta" FBgn0260860 Bet5 Blocked early in transport 5 http://flybase.org/reports/FBgn0260860 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000583159 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000004542 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000004542 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000583159 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity TRAPP complex ; GO:0030008 | inferred from biological aspect of ancestor with PANTHER:PTN000583159 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000004542 "CG1359, BET5, Bet5p, Bet5" "IPR007233:Trafficking protein particle complex subunit, IPR011012:Longin-like domain" CG1359 11-Aug-17 DroID_v2017_08 Drer\trappc1 "Scer\TRS23, Scer\BET5" "Cele\trpp-4, Cele\trpp-1, Cele\lec-12" Xtro\trappc1 Mmus\Trappc1 "Hsap\OSTC, Hsap\TRAPPC1" DRSC14600 IK 1.571367212 0.524431408 1.288070269 0.323657125 0.518423784 2.670901421 FBgn0066070 Su(var)2-6 Su(var)2-6 http://flybase.org/reports/FBgn0066070 gene - - - Su(var)2-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045960 Stalker\sORF Stalker element sORF http://flybase.org/reports/FBgn0045960 transposable_element_gene - - - Stalker\sORF - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265176 CR44241 - http://flybase.org/reports/FBgn0265176 non_protein_coding_gene - - - "CR44241, CG34187" - CR44241 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041174 Vhl von Hippel-Lindau http://flybase.org/reports/FBgn0041174 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KRW1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q15369 "protein ubiquitination ; GO:0016567 | inferred from direct assay open tracheal system development ; GO:0007424 | inferred from mutant phenotype protein export from nucleus ; GO:0006611 | inferred from mutant phenotype negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype trachea development ; GO:0060438 | inferred from mutant phenotype establishment or maintenance of polarity of follicular epithelium ; GO:0016334 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from genetic interaction with mgr mitotic spindle assembly ; GO:0090307 | inferred from genetic interaction with mgr regulation of cellular response to hypoxia ; GO:1900037 | inferred from mutant phenotype" VCB complex ; GO:0030891 | inferred from direct assay "dVHL, VHL, d-VHL, dmVHL, d-vhl, vhl, CG13221, BcDNA:RH61560, Vhl, DVhl, Dvhl" "IPR024053:von Hippel-Lindau disease tumour suppressor, beta domain, IPR002714:Von Hippel-Lindau tumour suppressor protein, IPR022772:von Hippel-Lindau disease tumour suppressor, beta/alpha domain" CG13221 11-Aug-17 DroID_v2017_08 "Drer\vhl, Drer\vhll" - Cele\vhl-1 Xtro\vhl Mmus\Vhl "Hsap\VHL, Hsap\VHLL" "cell migration defective,lethal,viable,stress response defective,partially lethal - majority die,visible,planar polarity defective,cell polarity defective,somatic clone,recessive,non-rescuable maternal effect,lethal - all die before end of first instar larval stage,some die during first instar larval stage,female sterile" "border follicle cell | oogenesis stage S10,border follicle cell | oogenesis stage S9,embryonic/larval trachea,embryonic/larval dorsal trunk,embryonic/larval dorsal branch,embryonic/larval lateral trunk,tracheal primordium,ectopic,tracheole,cell non-autonomous,presumptive embryonic/larval tracheal system,transverse connective primordium,visceral branch primordium,lateral trunk primordium,dorsal trunk primordium,trichogen cell,follicle cell,somatic clone,microtubule | somatic clone,embryonic/larval tracheal system,maternal effect,egg chamber,nurse cell,microtubulebtl.PS,heat sensitive" FBgn0265898 CR44687 - http://flybase.org/reports/FBgn0265898 non_protein_coding_gene - - - "CR44687, lincRNA.640, lincRNA.651" - CR44687 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025612 CG3062 - http://flybase.org/reports/FBgn0025612 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium organization ; GO:0044782 | inferred from biological aspect of ancestor with PANTHER:PTN002161271 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN002161271 "EG:84H4.5, CG3062" - CG3062 11-Aug-17 DroID_v2017_08 Drer\cfap126 - - - Mmus\Cfap126 Hsap\CFAP126 viable FBgn0028491 CG2930 - http://flybase.org/reports/FBgn0028491 protein_coding_gene "transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR000109, InterPro:IPR018456" oligopeptide transport ; GO:0006857 | inferred from electronic annotation with InterPro:IPR018456 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000109, InterPro:IPR018456" "BcDNA:GH06717, CG32787, CG32780, CG2930" "IPR000109:Proton-dependent oligopeptide transporter family, IPR020846:Major facilitator superfamily domain, IPR018456:PTR2 family proton/oligopeptide symporter, conserved site" CG2930 11-Aug-17 DroID_v2017_08 "Drer\slc15a1a, Drer\slc15a4, Drer\slc15a1b, Drer\slc15a2, Drer\si:ch211-190o6.3" Scer\PTR2 "Cele\pept-3, Cele\pept-1, Cele\pept-2" "Xtro\slc15a4, Xtro\slc15a2, Xtro\slc15a1" "Mmus\Slc15a3, Mmus\Slc15a5, Mmus\Slc15a4, Mmus\Slc15a1, Mmus\Slc15a2" "Hsap\SLC15A5, Hsap\SLC15A1, Hsap\SLC15A3, Hsap\SLC15A2, Hsap\SLC15A4" viable FBgn0005635 belt belt http://flybase.org/reports/FBgn0005635 - gene - - - belt - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005356 su(msm1) suppressor of msm1 http://flybase.org/reports/FBgn0005356 - gene - - - "su(m1[5A]), su(msm1)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267666 CR46004 - http://flybase.org/reports/FBgn0267666 non_protein_coding_gene - - - CR46004 - CR46004 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060586 l(3)S093902 lethal (3) S093902 http://flybase.org/reports/FBgn0060586 gene - - - "0939/02, l(3)S093902" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0069918 CG41134 - http://flybase.org/reports/FBgn0069918 protein_coding_gene - - - CG41134 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065949 l(2)SH0086 lethal (2) SH0086 http://flybase.org/reports/FBgn0065949 gene - - - "l(2)SH0086, l(2)SH2 0086" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016962 umpA uncoordinated with mechanoreceptor potential A http://flybase.org/reports/FBgn0016962 - gene - - - umpA - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053369 5SrRNA:CR33369 5SrRNA:CR33369 http://flybase.org/reports/FBgn0053369 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33369, 5SrRNA:CR33369" - CR33369 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026336 Su(tor)2-68-20 Su(tor)2-68-20 http://flybase.org/reports/FBgn0026336 - gene - - - Su(tor)2-68-20 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064181 hh-CMM hh-CMM http://flybase.org/reports/FBgn0064181 regulatory_region - - - "hh CMM, hh-CMM" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262759 Mst77Y-10Psi Male-specific pseudogene 77Y 10 http://flybase.org/reports/FBgn0262759 pseudogene_attribute - - - Mst77Y-10Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016057 prd6 prd6 http://flybase.org/reports/FBgn0016057 - gene - - - prd6 - - 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage , embryonic stage | <8-12 hr " FBgn0026149 BCL7-like BCL7-like http://flybase.org/reports/FBgn0026149 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG17252, BCL7-like, Bcl7-like" IPR006804:BCL7 CG17252 11-Aug-17 DroID_v2017_08 "Drer\bcl7a, Drer\bcl7bb, Drer\bcl7ba" - Cele\bcl-7 "Xtro\bcl7c, Xtro\bcl7b, Xtro\bcl7a" "Mmus\Bcl7b, Mmus\Bcl7a, Mmus\Bcl7c" "Hsap\BCL7B, Hsap\BCL7C, Hsap\BCL7A" "viable,fertile,visible" mesothoracic tergum FBgn0266968 CR45419 - http://flybase.org/reports/FBgn0266968 non_protein_coding_gene - - - CR45419 - CR45419 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264373 CR43825 - http://flybase.org/reports/FBgn0264373 non_protein_coding_gene - - - CR43825 - CR43825 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060634 l(3)S085005b lethal (3) S085005b http://flybase.org/reports/FBgn0060634 gene - - - "0850/05, l(3)S085005b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001900 l(2)22Aa lethal (2) 22Aa http://flybase.org/reports/FBgn0001900 - gene - - - "l(2)neh-14, l(2)neh14, l(2)22Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024433 Dl-l Delta-like http://flybase.org/reports/FBgn0024433 - gene molecular_function ; GO:0003674 | no biological data available gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Dl-l - - 11-Aug-17 DroID_v2017_08 - - - - - - embryo FBgn0053489 CG33489 - http://flybase.org/reports/FBgn0053489 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6110, CG33489" - CG33489 11-Aug-17 DroID_v2017_08 Drer\efhb - - - Mmus\Efhb Hsap\EFHB "viable,fertile" FBgn0030025 CG2147 - http://flybase.org/reports/FBgn0030025 protein_coding_gene - - - "BcDNA:LP02728, CG2147" - CG2147 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030836 CG8664 - http://flybase.org/reports/FBgn0030836 protein_coding_gene - - - CG8664 - CG8664 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014910 anon-4Fd anon-4Fd http://flybase.org/reports/FBgn0014910 - gene - - - anon-4Fd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027885 Aac11 Aac11 http://flybase.org/reports/FBgn0027885 FBgn0022116 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Acn negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype inferred from genetic interaction with E2f1 inferred from genetic interaction with Rbf neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with HGNC:594 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9BZZ5 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:594 "l(2)k06710, BcDNA.LD09852, CG6582, BcDNA:LD09852, Aac11, Api5, AAC-11" "IPR008383:Apoptosis inhibitory 5, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG6582 11-Aug-17 DroID_v2017_08 Drer\api5 - - Xtro\api5 Mmus\Api5 Hsap\API5 "lethal,recessive,visible,neuroanatomy defective" "wing blade,embryonic/larval neuroblast,ganglion mother cell" FBgn0265219 shf::Hsap\WIF1 - http://flybase.org/reports/FBgn0265219 engineered_fusion_gene - - - shf::Hsap\WIF1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034046 tun tungus http://flybase.org/reports/FBgn0034046 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ; GO:0016811 | inferred from electronic annotation with InterPro:IPR023128" olfactory learning ; GO:0008355 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype - "CG8253, BcDNA:LD38553, tun, Ntaq1" "IPR023128:Protein N-terminal glutamine amidohydrolase, alpha beta roll" CG8253 11-Aug-17 DroID_v2017_08 Drer\wdyhv1 - Cele\R06C7.6 Xtro\wdyhv1 Mmus\Wdyhv1 Hsap\WDYHV1 "viable,memory defective" FBgn0036273 INPP5E Inositol polyphosphate 5-phosphatase E http://flybase.org/reports/FBgn0036273 protein_coding_gene "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ; GO:0004439 | inferred from sequence or structural similarity with SGD:S000001264 inositol trisphosphate phosphatase activity ; GO:0046030 | non-traceable author statement" protein localization to cilium ; GO:0061512 | inferred from mutant phenotype phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from sequence or structural similarity with SGD:S000001264 dephosphorylation ; GO:0016311 | non-traceable author statement sensory perception of sound ; GO:0007605 | inferred from mutant phenotype ciliary base ; GO:0097546 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with SGD:S000001264 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000001264 "IPP, CG10426, INPP5E, INPPE5, dInpp5e" "IPR000300:Inositol polyphosphate-related phosphatase, IPR005135:Endonuclease/exonuclease/phosphatase" CG10426 11-Aug-17 DroID_v2017_08 "Drer\inpp5e, Drer\ocrl, Drer\inppl1a, Drer\inpp5kb, Drer\inpp5ka, Drer\inpp5b, Drer\inpp5jb, Drer\sh2d1aa, Drer\inpp5j, Drer\inppl1b, Drer\inpp5d" "Scer\INP54, Scer\INP52, Scer\INP51, Scer\INP53" "Cele\cil-1, Cele\inpp-1" "Xtro\inpp5b, Xtro\inpp5k, Xtro\inpp5j, Xtro\inpp5d, Xtro\sec16a" "Mmus\Sh2d1b1, Mmus\Inpp5e, Mmus\Inpp5k, Mmus\Ocrl, Mmus\Sh2d1a, Mmus\Inpp5b, Mmus\Sh2d1b2, Mmus\Inpp5d, Mmus\Inpp5j, Mmus\Inppl1" "Hsap\INPP5K, Hsap\SH2D1B, Hsap\INPPL1, Hsap\INPP5E, Hsap\OCRL, Hsap\INPP5J, Hsap\INPP5B, Hsap\INPP5D" "neuroanatomy defective,viable" "anterior fascicle & synapse,synapse,intersegmental nerve" FBgn0025002 E(var)70-2 E(var)70-2 http://flybase.org/reports/FBgn0025002 - gene - - - E(var)70-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065230 l(2)SH2183 lethal (2) SH2183 http://flybase.org/reports/FBgn0065230 gene - - - "l(2)SH2183, l(2)SH2 2183" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002795 ms(1)3 male sterile (1) 3 http://flybase.org/reports/FBgn0002795 - gene - - - ms(1)3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile" FBgn0085683 CG41552 - http://flybase.org/reports/FBgn0085683 protein_coding_gene - - - CG41552 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031770 CG13995 - http://flybase.org/reports/FBgn0031770 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "anon-WO0170980.170, anon-WO0170980.169, CG13995" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG13995 11-Aug-17 DroID_v2017_08 Drer\cckar - "Cele\srv-29, Cele\srv-28, Cele\ZK863.1, Cele\srv-25, Cele\srv-24, Cele\srv-27, Cele\srv-19, Cele\ops-1, Cele\C50H11.13, Cele\ntr-1, Cele\srv-30, Cele\srv-32, Cele\srv-22, Cele\srv-26, Cele\C04C3.6, Cele\ntr-2, Cele\srv-21, Cele\T01B11.1, Cele\C54E10.3, Cele\srv-31, Cele\srv-17" - - - viable FBgn0038515 CG5823 - http://flybase.org/reports/FBgn0038515 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000000902 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "cuticle development ; GO:0042335 | inferred from genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630005 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000630005 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000000902 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from sequence or structural similarity with SGD:S000000902" endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with SGD:S000000902 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000630005 CG5823 "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG5823 11-Aug-17 DroID_v2017_08 Drer\ube2j2 Scer\UBC6 "Cele\ubc-15, Cele\ubc-26" Xtro\ube2j2 Mmus\Ube2j2 Hsap\UBE2J2 "viable,fertile" FBgn0001663 l(1)E34 lethal (1) E34 http://flybase.org/reports/FBgn0001663 - gene - - - "l(1)E34[ts], l(1)E34" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" FBgn0051664 CG31664 - http://flybase.org/reports/FBgn0051664 protein_coding_gene - - - "CG15622, CG31664" IPR032062:Protein of unknown function DUF4803 CG31664 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069161 mcl(3)Z1956 mcl(3)Z1956 http://flybase.org/reports/FBgn0069161 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1956 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0085223 CG34194 - http://flybase.org/reports/FBgn0085223 protein_coding_gene serine C-palmitoyltransferase activity ; GO:0004758 | contributes_to inferred from sequence or structural similarity with HGNC:20361 biological_process ; GO:0008150 | no biological data available serine C-palmitoyltransferase complex ; GO:0017059 | inferred from sequence or structural similarity with HGNC:20361 CG34194 IPR024512:Small subunit of serine palmitoyltransferase-like CG34194 11-Aug-17 DroID_v2017_08 "Drer\sptssa, Drer\sptssb" - Cele\F13H10.8 "Xtro\sptssb, Xtro\sptssa" "Mmus\Sptssa, Mmus\Sptssb" "Hsap\SPTSSB, Hsap\SPTSSA" FBgn0267326 Ntl Neurotransmitter transporter-like http://flybase.org/reports/FBgn0267326 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 glycine transmembrane transporter activity ; GO:0015187 | inferred from sequence or structural similarity with HGNC:11051 inferred from mutant phenotype neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT L-proline transmembrane transporter activity ; GO:0015193 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT glycine import ; GO:0036233 | inferred from mutant phenotype flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype proline transport ; GO:0015824 | inferred from sequence model positive regulation of protein polyglycylation ; GO:1903346 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 "Ntl, ntl, CG7075, Mp" IPR000175:Sodium:neurotransmitter symporter CG7075 11-Aug-17 DroID_v2017_08 "Drer\slc6a18, Drer\slc6a4a, Drer\slc6a1l, Drer\slc6a16b, Drer\slc6a14, Drer\slc6a1b, Drer\slc6a19b, Drer\slc6a6b, Drer\slc6a13l, Drer\slc6a2, Drer\slc6a4b, Drer\slc6a9, Drer\slc6a16a, Drer\slc6a19a.2, Drer\si:ch211-132b12.6, Drer\slc6a5, Drer\slc6a8, Drer\si:ch211-132b12.2, Drer\slc6a1a, Drer\slc6a13, Drer\zgc:158225, Drer\si:ch211-132b12.1, Drer\si:ch211-117c9.5, Drer\slc6a15, Drer\slc6a6a, Drer\slc6a17, Drer\slc6a11a, Drer\slc6a13, Drer\slc6a19a.1" - "Cele\snf-3, Cele\snf-9, Cele\dat-1, Cele\snf-2, Cele\snf-12, Cele\snf-6, Cele\mod-5, Cele\snf-11" "Xtro\slc6a13, Xtro\LOC100127682, Xtro\slc6a15, Xtro\slc6a17, Xtro\slc6a7, Xtro\slc6a14.2, Xtro\slc6a3, Xtro\slc6a8, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a9, Xtro\slc6a19, Xtro\slc6a16, Xtro\slc6a1, Xtro\slc6a5, Xtro\slc6a12, Xtro\slc6a2" "Mmus\Slc6a21, Mmus\Slc6a4, Mmus\Slc6a20b, Mmus\Slc6a8, Mmus\Slc6a6, Mmus\Slc6a18, Mmus\Slc6a13, Mmus\Slc6a15, Mmus\Slc6a12, Mmus\Slc6a9, Mmus\Slc6a16, Mmus\Slc6a2, Mmus\Slc6a20a, Mmus\Slc6a19, Mmus\Slc6a1, Mmus\Slc6a3, Mmus\Slc6a5, Mmus\Slc6a17, Mmus\Slc6a7, Mmus\Slc6a14, Mmus\Slc6a11" "Hsap\SLC6A1, Hsap\SLC6A16, Hsap\SLC6A3, Hsap\SLC6A13, Hsap\SLC6A8, Hsap\SLC6A20, Hsap\SLC6A6, Hsap\SLC6A14, Hsap\SLC6A17, Hsap\SLC6A12, Hsap\SLC6A15, Hsap\SLC6A18, Hsap\SLC6A4, Hsap\SLC6A2, Hsap\SLC6A5, Hsap\SLC6A7, Hsap\SLC6A9, Hsap\SLC6A19, Hsap\SLC6A11" FBgn0060664 l(3)S080906 lethal (3) S080906 http://flybase.org/reports/FBgn0060664 gene - - - "0809/06, l(3)S080906" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0260659 CG42542 - http://flybase.org/reports/FBgn0260659 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available - "CG42542, CG4196, CG31303" IPR001727:Gdt1 family CG42542 11-Aug-17 DroID_v2017_08 Drer\tmem165 Scer\GDT1 Cele\Y54F10AL.1 Xtro\tmem165 Mmus\Tmem165 Hsap\TMEM165 DRSC22264 I 1.116935161 2.92967633 0.981846972 1.068903056 0.844129052 -0.365539976 FBgn0265890 CR44679 - http://flybase.org/reports/FBgn0265890 non_protein_coding_gene - - - "CR44679, lincRNA.630" - CR44679 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029061 l(1)G0372 lethal (1) G0372 http://flybase.org/reports/FBgn0029061 gene - - - l(1)G0372 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025732 sca::Hsap\FGG sca::Hsap\FGG http://flybase.org/reports/FBgn0025732 - engineered_fusion_gene - - - sca::Hsap\FGG - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0025563 anon-23Cc anon-23Cc http://flybase.org/reports/FBgn0025563 - gene - - - "c2.5, anon-23Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025764 l(3)89Df lethal (3) 89Df http://flybase.org/reports/FBgn0025764 - gene - - - "l(3)M2922, l(3)89Df" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0284243 betaTub56D beta-Tubulin at 56D http://flybase.org/reports/FBgn0284243 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002453, InterPro:IPR008280, InterPro:IPR017975 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity structural constituent of cytoskeleton ; GO:0005200 | inferred from direct assay" muscle attachment ; GO:0016203 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype microtubule ; GO:0005874 | non-traceable author statement microtubule ; GO:0005874 | inferred from direct assay microtubule ; GO:0005874 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay neuromuscular junction ; GO:0031594 | microtubule ; GO:0005874 | "betaTub56D, betatub56D, CG9277, beta-tubulin56D, beta-tub56D, Tub2D, beta-Tub56D, beta-Tub, beta1-tub, beta1-Tubulin, beta-tub, Tubulin, beta1, BETA 56D, beta1tub, Dmbeta1, beta1Tub, beta1t, B1t, T, 1t, beta[[1]] tubulin, beta[[1]]-tubulin, beta56D, DTB2, betaTub1, Tub, beta, betatub(56D), betaTub, A1ZBL0_DROME, TBB1_DROME, l(2)k00705, TUB56D, tubulin" "IPR000217:Tubulin, IPR002453:Beta tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain, IPR013838:Beta tubulin, autoregulation binding site" CG9277 11-Aug-17 DroID_v2017_08 "Drer\tubb2, Drer\zgc:55461, Drer\zgc:65894, Drer\tubb1, Drer\tubb5, Drer\zgc:153426, Drer\tubb4b, Drer\tubb2b, Drer\zgc:153264, Drer\tubb6" Scer\TUB2 "Cele\ben-1, Cele\tbb-2, Cele\mec-7, Cele\tbb-1, Cele\tbb-4" "Xtro\tubb4b, Xtro\tubb3, Xtro\tubb6, Xtro\tube1, Xtro\tubb4a, Xtro\tubb2b, Xtro\tubb" "Mmus\Tubb4a, Mmus\Tubb4b, Mmus\Tubb2b, Mmus\Tubb6, Mmus\Tubb5, Mmus\Tube1, Mmus\Tubb2a, Mmus\Tubb1, Mmus\Tubb3" "Hsap\TUBB2B, Hsap\TUBB, Hsap\TUBB1, Hsap\TUBB2A, Hsap\TUBE1, Hsap\TUBB4B, Hsap\TUBB3, Hsap\TUBB6, Hsap\TUBB8, Hsap\TUBB4A" "lethal,recessive" FBgn0069312 X-206-23 X-206-23 http://flybase.org/reports/FBgn0069312 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-206-23 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0036689 CG7730 - http://flybase.org/reports/FBgn0036689 protein_coding_gene - learning or memory ; GO:0007611 | inferred from biological aspect of ancestor with PANTHER:PTN000473820 - CG7730 IPR031962:Domain of unknown function DUF4781 CG7730 11-Aug-17 DroID_v2017_08 - - Cele\F02C12.1 - - - viable FBgn0025634 CG13367 - http://flybase.org/reports/FBgn0025634 FBgn0013389 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000330972 "EG:115C2.8, anon-1BCb, CG13367" - CG13367 11-Aug-17 DroID_v2017_08 Drer\gatad1 - - Xtro\gatad1 Mmus\Gatad1 Hsap\GATAD1 " adult stage , embryonic stage " viable FBgn0263874 CR43721 - http://flybase.org/reports/FBgn0263874 non_protein_coding_gene - - - "CR43721, CG43268" - CR43721 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053349 ppk25 pickpocket 25 http://flybase.org/reports/FBgn0053349 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 protein binding ; GO:0005515 | inferred from physical interaction with CheB42a male courtship behavior ; GO:0008049 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 response to pheromone ; GO:0019236 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with CheB42a integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG15242, CG33349, ppk25, llz" IPR001873:Epithelial sodium channel CG33349 11-Aug-17 DroID_v2017_08 "Drer\asic1c, Drer\asic2, Drer\asic1b, Drer\asic4a, Drer\asic1a, Drer\asic4b" - "Cele\acd-4, Cele\acd-1, Cele\acd-2, Cele\del-1, Cele\flr-1, Cele\del-8, Cele\degt-1, Cele\del-7, Cele\del-9, Cele\delm-1, Cele\delm-2, Cele\acd-5, Cele\acd-3" "Xtro\scnn1d, Xtro\scnn1g, Xtro\scnn1a, Xtro\scnn1b, Xtro\asic1, Xtro\asic5, Xtro\asic4" "Mmus\Scnn1b, Mmus\Scnn1g, Mmus\Scnn1a, Mmus\Asic3, Mmus\Asic4, Mmus\Asic5, Mmus\Asic2, Mmus\Asic1" "Hsap\ASIC4, Hsap\ASIC2, Hsap\SCNN1D, Hsap\SCNN1G, Hsap\ASIC1, Hsap\ASIC5, Hsap\ASIC3, Hsap\SCNN1B, Hsap\SCNN1A" "courtship behavior defective,male,heat sensitive,viable,lethal" FBgn0002437 l(3)L6B lethal (3) L6B http://flybase.org/reports/FBgn0002437 - gene - - - l(3)L6B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069983 BG02330 BG02330 http://flybase.org/reports/FBgn0069983 gene - - - BG02330 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0044809 TotZ Turandot Z http://flybase.org/reports/FBgn0044809 protein_coding_gene - response to bacterium ; GO:0009617 | inferred from expression pattern cellular response to heat ; GO:0034605 | inferred from expression pattern response to UV ; GO:0009411 | inferred from direct assay response to heat ; GO:0009408 | inferred from direct assay response to oxidative stress ; GO:0006979 | inferred from direct assay cellular response to UV ; GO:0034644 | inferred from expression pattern cellular response to oxidative stress ; GO:0034599 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence or structural similarity with TotA extracellular region ; GO:0005576 | inferred from sequence model "tot, CG31507, TotZ, Totz" IPR010825:Stress-inducible humoral factor Turandot CG31507 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028974 xmas-2 xmas-2 http://flybase.org/reports/FBgn0028974 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VYX1 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from direct assay transcription export complex 2 ; GO:0070390 | inferred from direct assay nuclear periphery ; GO:0034399 | inferred from direct assay "CG8919, CG32562, xmas-2, Xmas-2" "IPR000504:RNA recognition motif domain, IPR005062:SAC3/GANP/THP3, IPR034366:Protein xmas-2, RNA recognition motif" CG32562 11-Aug-17 DroID_v2017_08 "Drer\mcm3ap, Drer\si:zfos-452g4.1" Scer\SAC3 "Cele\tag-115, Cele\F20D12.2" Xtro\mcm3ap "Mmus\Mcm3ap, Mmus\Sac3d1" "Hsap\SAC3D1, Hsap\MCM3AP" "viable,visible" trichogen cell FBgn0000931 fs(2)A1 female sterile (2) A1 http://flybase.org/reports/FBgn0000931 - gene - - - fs(2)A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0042174 CR18854 - http://flybase.org/reports/FBgn0042174 pseudogene_attribute RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005123 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 - "CG13122, CG18854, CR18854" "IPR004088:K Homology domain, type 1, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CR18854 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval hemocyte | third instar larval stage DRSC02702 IE 1.646486754 1.234347995 -1.518121469 -0.008514232 1.11953391 -1.131198916 FBgn0030435 CG4645 - http://flybase.org/reports/FBgn0030435 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000302438 - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006977 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000302438 CG4645 IPR006977:Yip1 domain CG4645 11-Aug-17 DroID_v2017_08 "Drer\yipf2, Drer\yipf1" Scer\YIP5 Cele\Y25C1A.7 "Xtro\yipf2, Xtro\yipf1" "Mmus\Yipf2, Mmus\Yipf1" "Hsap\YIPF1, Hsap\YIPF2" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0052829 CG32829 - http://flybase.org/reports/FBgn0052829 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32829 IPR031959:Protein of unknown function DUF4779 CG32829 11-Aug-17 DroID_v2017_08 - - "Cele\C41G7.6, Cele\E03H12.5" - - - viable DRSC22805 IE 3.24409376 1.07349094 5.831226194 1.028555556 -0.334364748 1.193639713 FBgn0011858 tRNA:Phe-GAA-1-8 transfer RNA:Phenylalanine-GAA 1-8 http://flybase.org/reports/FBgn0011858 "FBgn0011856, FBgn0051586, FBgn0060232" tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "tRNA-Phe-2, phe-tRNA-2, AE002708.trna6-PheGAA, tRNA:F:GAA:AE002708-b, CR31586, tRNA:phe2:89BC, chr3R.trna12-PheGAA, tRNA-Phe-GAA-1-8, tRNA:Phe-GAA-1-8, tRNA:F2:89BC, UUC" - CR31586 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041584 whsc1 whsc1 http://flybase.org/reports/FBgn0041584 gene - - - "Dm_whsc1, whsc1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260017 troya troya http://flybase.org/reports/FBgn0260017 gene - - - troya - - 11-Aug-17 DroID_v2017_08 - - - - - - chorion | germline clone FBgn0267059 CR45503 - http://flybase.org/reports/FBgn0267059 non_protein_coding_gene - - - "CR45503, Dm_X:95517" - CR45503 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027969 l(3)S144405 lethal (3) S144405 http://flybase.org/reports/FBgn0027969 gene - - - "1444/05, l(3)S144405" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0010492 l(2)01482 lethal (2) 01482 http://flybase.org/reports/FBgn0010492 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)01482 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially,rescuable maternal effect,partially lethal - majority die" "embryonic/first instar larval cuticle,head,abdomen,posterior" FBgn0011380 l(3)j5B6 lethal (3) j5B6 http://flybase.org/reports/FBgn0011380 - gene - - - l(3)j5B6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053140 CG33140 - http://flybase.org/reports/FBgn0053140 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG11074, BcDNA:AT21895, CG33140" "IPR032707:MYCBP-associated protein, IPR013783:Immunoglobulin-like fold" CG33140 11-Aug-17 DroID_v2017_08 Drer\mycbpap - - - Mmus\Mycbpap - viable FBgn0014465 Cp7Fb Chorion protein b at 7F http://flybase.org/reports/FBgn0014465 FBgn0030044 protein_coding_gene - chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern inferred from genomic context chorion ; GO:0042600 | inferred by curator from GO:0007304 inferred from genomic context "Cp7Fb, CG15350, C, B, cp7Fb" - CG15350 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && oogenesis stage | stage S10B-13 , oogenesis stage | stage S10-12 " follicle cell

FBgn0014094 anon-3Aa anon-3Aa http://flybase.org/reports/FBgn0014094 - gene - - - anon-3Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , adult stage " FBgn0264700 CR43969 - http://flybase.org/reports/FBgn0264700 non_protein_coding_gene - - - CR43969 - CR43969 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052643 CG32643 - http://flybase.org/reports/FBgn0052643 protein_coding_gene - - - "NEST:bs08h10, CG32643" - CG32643 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060335 l(3)S144608 lethal (3) S144608 http://flybase.org/reports/FBgn0060335 gene - - - "1446/08, l(3)S144608" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0023473 anon-30Fa anon-30Fa http://flybase.org/reports/FBgn0023473 - gene - - - anon-30Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061073 l(3)S016704b lethal (3) S016704b http://flybase.org/reports/FBgn0061073 gene - - - "0167/04, l(3)S016704b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022725 p22 p22 http://flybase.org/reports/FBgn0022725 - gene - - - p22 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000708 fltN flight defective N http://flybase.org/reports/FBgn0000708 - gene - - - fltN - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0004801 fs(2)ltoRG3 female sterile (2) ltoRG3 http://flybase.org/reports/FBgn0004801 - gene molecular_function ; GO:0003674 | no biological data available ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoRG3 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0266671 Sec6 Secretory 6 http://flybase.org/reports/FBgn0266671 protein_coding_gene SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000480155 SNARE binding ; GO:0000149 | inferred from sequence or structural similarity with SGD:S000001330 protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000480155 exocytosis ; GO:0006887 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity protein localization to cell cortex ; GO:0072697 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype exocyst localization ; GO:0051601 | inferred from biological aspect of ancestor with PANTHER:PTN000480155 plasma membrane organization ; GO:0007009 | inferred from mutant phenotype synaptic vesicle targeting ; GO:0016080 | non-traceable author statement synaptic vesicle docking ; GO:0016081 | non-traceable author statement border follicle cell migration ; GO:0007298 | inferred from mutant phenotype rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype Golgi to plasma membrane protein transport ; GO:0043001 | inferred from mutant phenotype exocyst ; GO:0000145 | inferred from direct assay exocyst ; GO:0000145 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay zonula adherens ; GO:0005915 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay exocyst ; GO:0000145 | inferred from biological aspect of ancestor with PANTHER:PTN000480155 exocyst ; GO:0000145 | non-traceable author statement rhabdomere ; GO:0016028 | inferred from direct assay "sec6, Sec6, CG5341, Dsec6, sec 6, Sec6p, dsec6" IPR010326:Exocyst complex component EXOC3/Sec6 CG5341 11-Aug-17 DroID_v2017_08 "Drer\exoc3l2b, Drer\exoc3l2a, Drer\tnfaip2b, Drer\exoc3l4, Drer\exoc3l1, Drer\si:dkey-45k15.1, Drer\tnfaip2a, Drer\exoc3" Scer\SEC6 Cele\sec-6 "Xtro\exoc3, Xtro\exoc3l1, Xtro\tnfaip2" "Mmus\Exoc3l2, Mmus\Exoc3, Mmus\Tnfaip2, Mmus\Exoc3l4, Mmus\Exoc3l" "Hsap\EXOC3L4, Hsap\EXOC3L1, Hsap\TNFAIP2, Hsap\EXOC3, Hsap\EXOC3L2" DRSC06932 EK -0.322984004 -0.482431596 -2.177827747 1.107653421 -0.082435357 2.222515112 FBgn0002123 l(2)hst lethal (2) histolytic http://flybase.org/reports/FBgn0002123 - gene - - - l(2)hst - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0265471 CR44364 - http://flybase.org/reports/FBgn0265471 non_protein_coding_gene - - - CR44364 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264828 CR44036 - http://flybase.org/reports/FBgn0264828 non_protein_coding_gene - - - CR44036 - CR44036 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262462 mir-iab-4 mir-iab-4 stem loop http://flybase.org/reports/FBgn0262462 miRNA_gene - - - "miR-iab-4, mir-iab-4-5p, mir-iab-4, iab-4, mir-iab4, miR-iab-4-3p, miR-iab-4-5p, miR-iab4, MIR-iab4, CR43043, iab-4-5p, CR33624, iab-4-3p, CR33623, mir-iab-4-3p, MIR-iab-4, dme-iab-4, dme-miR-iab-4" - CR43043 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,homeotic" "haltere,wing,wing margin" FBgn0013508 l(1)U3 lethal (1) U3 http://flybase.org/reports/FBgn0013508 - gene - - - "U-3, l(1)U3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264440 CR43858 - http://flybase.org/reports/FBgn0264440 non_protein_coding_gene - - - CR43858 - CR43858 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027194 l(2)51Fb lethal (2) 51Fb http://flybase.org/reports/FBgn0027194 - gene - - - l(2)51Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,lethal" FBgn0013702 mt:tRNA:Pro-TGG mitochondrial transfer RNA:Proline-TGG http://flybase.org/reports/FBgn0013702 FBgn0002867 tRNA_gene - - - "CR34088, mtdbD00006310, mt:tRNA:Pro-TGG, mt:tRNA:P" - CR34088 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086400 BG02439 - http://flybase.org/reports/FBgn0086400 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02439 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective,sleep defective" FBgn0033475 CG12129 - http://flybase.org/reports/FBgn0033475 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 - - "cg12129, CG12129" "IPR019510:Protein kinase A anchor protein, nuclear localisation signal domain, IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR009097:Cyclic phosphodiesterase" CG12129 11-Aug-17 DroID_v2017_08 "Drer\ascc1, Drer\akap7" - Cele\C23H3.3 "Xtro\akap7, Xtro\ascc1" "Mmus\Ascc1, Mmus\Akap7" "Hsap\ASCC1, Hsap\AKAP7" viable FBgn0082346 HM431 HM431 http://flybase.org/reports/FBgn0082346 gene - - - HM431 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036236 CG6931 - http://flybase.org/reports/FBgn0036236 protein_coding_gene - - - CG6931 IPR018958:SMI1/KNR4-like domain CG6931 11-Aug-17 DroID_v2017_08 Drer\tpgs2 - - Xtro\tpgs2 Mmus\Tpgs2 Hsap\TPGS2 viable FBgn0050285 CG30285 - http://flybase.org/reports/FBgn0050285 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30285 - CG30285 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065567 l(2)SH0977 lethal (2) SH0977 http://flybase.org/reports/FBgn0065567 gene - - - "l(2)SH0977, l(2)SH2 0977" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065291 l(2)SH2011 lethal (2) SH2011 http://flybase.org/reports/FBgn0065291 gene - - - "l(2)SH2011, l(2)SH2 2011" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267446 Su(Ste):CR45796 Supressor of Stellate:CR45796 http://flybase.org/reports/FBgn0267446 non_protein_coding_gene - - - "Su(Ste):CR45796, CR45796" - CR45796 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267001 Ten-a Tenascin accessory http://flybase.org/reports/FBgn0267001 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011041 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O61307 protein homodimerization activity ; GO:0042803 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from direct assay self proteolysis ; GO:0097264 | inferred from electronic annotation with InterPro:IPR022385 central complex development ; GO:0048036 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from direct assay synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype maintenance of presynaptic active zone structure ; GO:0048790 | inferred from mutant phenotype positive regulation of heterotypic cell-cell adhesion ; GO:0034116 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype presynaptic membrane organization ; GO:0097090 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from direct assay synaptic target attraction ; GO:0016200 | inferred from mutant phenotype regulation of homotypic cell-cell adhesion ; GO:0034110 | inferred from direct assay positive regulation of locomotion ; GO:0040017 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype postsynaptic membrane organization ; GO:0001941 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype synaptic vesicle membrane organization ; GO:0048499 | inferred from mutant phenotype cytoskeleton of presynaptic active zone ; GO:0048788 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence model presynaptic active zone ; GO:0048786 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity neuromuscular junction ; GO:0031594 | inferred from direct assay presynaptic membrane ; GO:0042734 | inferred from direct assay "Ten-a, CG42338, ten-a, cbd, CG2578, ten[a], Dmtena, tenA(AT)[[14]], 1.2, Ten[a], tenA, CG18182, CG2590, Ten11A, CG11270, CG32659, DmtenA, CG12720, CG15733" "IPR011041:Soluble quinoprotein glucose/sorbosone dehydrogenase, IPR022385:Rhs repeat-associated core, IPR011042:Six-bladed beta-propeller, TolB-like, IPR000742:EGF-like domain, IPR006530:YD repeat, IPR013032:EGF-like, conserved site, IPR013111:EGF-like domain, extracellular, IPR028916:Tox-GHH domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG42338 11-Aug-17 DroID_v2017_08 "Drer\tenm3, Drer\si:dkey-34l15.2, Drer\tnr, Drer\si:ch211-12m10.1, Drer\tenm4, Drer\tnw, Drer\tenm1, Drer\si:dkey-237h12.3, Drer\zgc:153720, Drer\tnc" - "Cele\drd-2, Cele\ten-1, Cele\F28B4.3" "Xtro\tnc, Xtro\tnr, Xtro\tenm4, Xtro\tnxb, Xtro\tnn" "Mmus\Tnxb, Mmus\Tnn, Mmus\Tenm2, Mmus\Tnc, Mmus\Tenm1, Mmus\Tenm4, Mmus\Tenm3, Mmus\Tnr" "Hsap\TENM1, Hsap\TENM2, Hsap\TENM3, Hsap\TENM4, Hsap\TNN, Hsap\TNC, Hsap\TNR" FBgn0051609 CG31609 - http://flybase.org/reports/FBgn0051609 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "anon-AE003623.1, CG31609" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG31609 11-Aug-17 DroID_v2017_08 "Drer\paplnb, Drer\wu:fb59d01, Drer\paplna" - "Cele\tag-290, Cele\C34F6.1" Xtro\papln "Mmus\Spint3, Mmus\Wfikkn1, Mmus\Papln, Mmus\Adamts6, Mmus\Adamtsl4, Mmus\Thsd4" "Hsap\PAPLN, Hsap\ADAMTSL4, Hsap\WFIKKN1, Hsap\ADAMTSL1, Hsap\ADAMTS6, Hsap\THSD4" viable FBgn0265048 cv-d crossveinless d http://flybase.org/reports/FBgn0265048 protein_coding_gene "lipid transporter activity ; GO:0005319 | inferred from electronic annotation with InterPro:IPR001747, InterPro:IPR011030, InterPro:IPR015255, InterPro:IPR015816, InterPro:IPR015819 heparan sulfate proteoglycan binding ; GO:0043395 | inferred from direct assay BMP binding ; GO:0036122 | inferred from physical interaction with dpp inferred from physical interaction with gbb coreceptor activity ; GO:0015026 | NOT inferred from direct assay" "lipid transport ; GO:0006869 | inferred from electronic annotation with InterPro:IPR001747, InterPro:IPR011030, InterPro:IPR015255, InterPro:IPR015816, InterPro:IPR015819 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype positive regulation of BMP signaling pathway ; GO:0030513 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay "CG31150, cv-d, CG9625, CG9627, CG9622, Cv-d" "IPR001747:Lipid transport protein, N-terminal, IPR011030:Vitellinogen, superhelical, IPR015816:Vitellinogen, beta-sheet N-terminal, IPR015819:Lipid transport protein, beta-sheet shell, IPR001846:von Willebrand factor, type D domain, IPR015255:Vitellinogen, open beta-sheet" CG31150 11-Aug-17 DroID_v2017_08 "Drer\vtg6, Drer\vtg2, Drer\vtg3, Drer\vtg1, Drer\si:dkey-4c23.3, Drer\vtg5, Drer\vtg7, Drer\vtg4" - "Cele\vit-5, Cele\vit-2, Cele\vit-4, Cele\vit-6, Cele\vit-3, Cele\vit-1" - - - "viable,fertile,visible,recessive" "posterior crossvein,wing margin,anterior crossvein" FBgn0013590 l(3)97Df lethal (3) 97Df http://flybase.org/reports/FBgn0013590 - gene - - - l(3)97Df - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0067869 Mod(Prat:bw)3-6 Mod(Prat:bw)3-6 http://flybase.org/reports/FBgn0067869 gene - - - "Mod-3-6, Mod(Prat:bw)3-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0061109 l(3)S007359 lethal (3) S007359 http://flybase.org/reports/FBgn0061109 gene - - - "0073/59, l(3)S007359" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033351 AIMP1 aaRS-interacting multifunctional protein 1 http://flybase.org/reports/FBgn0033351 protein_coding_gene tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 tRNA aminoacylation for protein translation ; GO:0006418 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 methionyl glutamyl tRNA synthetase complex ; GO:0017102 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 "AIMP1, CG8235" "IPR002547:tRNA-binding domain, IPR012340:Nucleic acid-binding, OB-fold" CG8235 11-Aug-17 DroID_v2017_08 "Drer\aimp1, Drer\yars, Drer\zgc:101853" Scer\ARC1 Cele\mars-1 "Xtro\aimp1, Xtro\yars" "Mmus\Aimp1, Mmus\Yars" "Hsap\AIMP1, Hsap\YARS" FBgn0000818 fs(1)K811 female sterile (1) K811 http://flybase.org/reports/FBgn0000818 - gene - - - fs(1)K811 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" dorsal appendage FBgn0010306 mod(r)1 modulator of rudimentary 1 http://flybase.org/reports/FBgn0010306 - gene - - - mod(r)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037836 CG14692 - http://flybase.org/reports/FBgn0037836 protein_coding_gene myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis - - CG14692 "IPR000048:IQ motif, EF-hand binding site, IPR003117:cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain" CG14692 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-116m6.4, Drer\LOC796000, Drer\si:dkeyp-117h8.2, Drer\atf7ip, Drer\pho, Drer\LOC100333206, Drer\rtn1b, Drer\ice1, Drer\si:ch211-242b18.1, Drer\LOC561423, Drer\cgnb" "Scer\RPO21, Scer\SEC16, Scer\NET1, Scer\ESC1" "Cele\F11E6.7, Cele\F19H6.3" "Xtro\kiaa1211, Xtro\rsf1, Xtro\rif1" "Mmus\Rif1, Mmus\Rtn4, Mmus\Atf7ip, Mmus\Cobll1, Mmus\Map4, Mmus\Cobl, Mmus\C530008M17Rik, Mmus\Cgn, Mmus\Polr2a, Mmus\Naca, Mmus\Rsf1" "Hsap\CCDC171, Hsap\RIF1, Hsap\ATF7IP, Hsap\RTN4, Hsap\COBLL1, Hsap\CDKN2AIP, Hsap\RTN3, Hsap\CGN, Hsap\KIAA1211, Hsap\COBL, Hsap\RSF1" viable FBgn0085601 CG41287 - http://flybase.org/reports/FBgn0085601 protein_coding_gene - - - CG41287 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052855 CG32855 - http://flybase.org/reports/FBgn0052855 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32855 - CG32855 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259643 B0915 - http://flybase.org/reports/FBgn0259643 gene - - - B0915 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein L3,wing" FBgn0069434 Egfr::Tl Egfr::Tl http://flybase.org/reports/FBgn0069434 engineered_fusion_gene - - - Egfr::Tl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266692 CR45182 - http://flybase.org/reports/FBgn0266692 non_protein_coding_gene - - - CR45182 - CR45182 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036258 eIF3l eukaryotic translation initiation factor 3 subunit l http://flybase.org/reports/FBgn0036258 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000326403 translation initiation factor activity ; GO:0003743 | contributes_to inferred from sequence or structural similarity with HGNC:18138 translational initiation ; GO:0006413 | inferred from sequence or structural similarity with HGNC:18138 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with HGNC:18138 cytosol ; GO:0005829 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000326403 "CG5642, eIF3l" "IPR011990:Tetratricopeptide-like helical domain, IPR019382:Translation initiation factor 3 complex subunit L" CG5642 11-Aug-17 DroID_v2017_08 Drer\eif3s6ip - "Cele\C03H5.5, Cele\C17G10.9" Xtro\eif3l Mmus\Eif3l Hsap\EIF3L viable DRSC10530 E -1.060752081 1.141647826 -1.868770931 0.12586034 0.128721837 0.798260958 FBgn0000162 baton baton http://flybase.org/reports/FBgn0000162 - gene - - - baton - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,visible,semidominant" "eye,tergite" FBgn0053247 Ste:CG33247 Ste:CG33247 http://flybase.org/reports/FBgn0053247 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay "CG32605, CG33247, Ste:CG33247" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33247 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0038568 CG14315 - http://flybase.org/reports/FBgn0038568 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14315 - CG14315 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085771 28SrRNA-Psi:CR40741 28S ribosomal RNA pseudogene:CR40741 http://flybase.org/reports/FBgn0085771 pseudogene_attribute - - - "CR40741, 28SrRNA-Psi:CR40741" - CR40741 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002351 l(3)87Dc lethal (3) 87Dc http://flybase.org/reports/FBgn0002351 - gene - - - "C1, B103, B-103, l(3)B103, l(3)B-103, l(3)87Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030569 CG9411 - http://flybase.org/reports/FBgn0030569 protein_coding_gene - - - CG9411 - CG9411 11-Aug-17 DroID_v2017_08 - - - - - Hsap\MBD6 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265820 CR44609 - http://flybase.org/reports/FBgn0265820 non_protein_coding_gene - - - "lincRNA.41, CR44609" - CR44609 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061510 fsl fusolo http://flybase.org/reports/FBgn0061510 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - fsl - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,sterile" "meiosis & nuclear chromosome,anaphase & condensed nuclear chromosomeBK10),telophase & nuclear chromosomeBK10),nuclear chromosomeBK10),nuclear chromosome,kinetochore,microtubule" FBgn0085529 CG40867 - http://flybase.org/reports/FBgn0085529 protein_coding_gene - - - CG40867 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034879 Rrp4 Rrp4 http://flybase.org/reports/FBgn0034879 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 "nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' ; GO:0034427 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 CUT catabolic process ; GO:0071034 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 polyadenylation-dependent snoRNA 3'-end processing ; GO:0071051 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 nuclear polyadenylation-dependent rRNA catabolic process ; GO:0071035 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 nuclear polyadenylation-dependent tRNA catabolic process ; GO:0071038 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 defense response to virus ; GO:0051607 | inferred from mutant phenotype exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000467 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription ; GO:0071049 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay ; GO:0043928 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype U4 snRNA 3'-end processing ; GO:0034475 | inferred from biological aspect of ancestor with PANTHER:PTN000481223" nuclear lamina ; GO:0005652 | inferred from direct assay exosome (RNase complex) ; GO:0000178 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000001111 inferred from direct assay cytoplasmic exosome (RNase complex) ; GO:0000177 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 "RRP4, CG3931, dRrp4, Rrp4, rrp4" "IPR025721:Exosome complex component, N-terminal domain, IPR012340:Nucleic acid-binding, OB-fold, IPR004088:K Homology domain, type 1, IPR026699:Exosome complex RNA-binding protein 1/RRP40/RRP4" CG3931 11-Aug-17 DroID_v2017_08 Drer\exosc2 Scer\RRP4 Cele\exos-2 Xtro\exosc2 Mmus\Exosc2 Hsap\EXOSC2 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266245 CR44940 - http://flybase.org/reports/FBgn0266245 non_protein_coding_gene - - - "CR44940, lincRNA.747" - CR44940 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062569 Mod(var)E1672 Mod(var)E1672 http://flybase.org/reports/FBgn0062569 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1672, Mod(var)E1672" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0002907 mus310 mutagen-sensitive 310 http://flybase.org/reports/FBgn0002907 - gene - - - "mus(3)310, mus310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "DNA repair defective,radiation sensitive,chemical sensitive,recessive" FBgn0026417 Hus1-like Hus1-like http://flybase.org/reports/FBgn0026417 - protein_coding_gene - meiotic DNA integrity checkpoint ; GO:0044778 | inferred from mutant phenotype mitotic DNA replication checkpoint ; GO:0033314 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 double-strand break repair via homologous recombination ; GO:0000724 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 mitotic DNA damage checkpoint ; GO:0044773 | inferred from mutant phenotype intra-S DNA damage checkpoint ; GO:0031573 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 female pronucleus assembly ; GO:0035038 | inferred from mutant phenotype nucleotide-excision repair ; GO:0006289 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 nucleolus ; GO:0005730 | inferred from electronic annotation with InterPro:IPR016580 cytoplasm ; GO:0005737 | inferred from direct assay checkpoint clamp complex ; GO:0030896 | inferred from direct assay site of double-strand break ; GO:0035861 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 "Hus1-like, Hus1, CG2525, hus1, DmHus1, Hus-1" "IPR007150:Checkpoint protein Hus1/Mec3, IPR016580:Cell cycle checkpoint, Hus1" CG2525 11-Aug-17 DroID_v2017_08 "Drer\zgc:162895, Drer\oraov1" Scer\MEC3 Cele\hus-1 Xtro\hus1 "Mmus\Oraov1, Mmus\Hus1, Mmus\Hus1b" "Hsap\ORAOV1, Hsap\HUS1, Hsap\HUS1B" "viable,fertile,female sterile,radiation resistant,chemical sensitive,planar polarity defective" "wing,posterior compartment,nucleus110),egg,nucleus,oocyte" FBgn0040797 CG13066 - http://flybase.org/reports/FBgn0040797 protein_coding_gene - - - CG13066 - CG13066 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260781 2-10 - http://flybase.org/reports/FBgn0260781 gene - - - 2-10 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0001224 Hsp23 Heat shock protein 23 http://flybase.org/reports/FBgn0001224 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with lwr unfolded protein binding ; GO:0051082 | inferred from sequence model unfolded protein binding ; GO:0051082 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay cold acclimation ; GO:0009631 | inferred from expression pattern response to heat ; GO:0009408 | inferred from direct assay protein refolding ; GO:0042026 | inferred from direct assay chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model microtubule associated complex ; GO:0005875 | inferred from direct assay "Dmel20.6, Hsp23, CG4463, hsp23, HSP23/IAP, DmHsp23, hsp23/22, hsp 23K, hsp 22K, 23, hsp 23, Hsp-23, HSP23, small hsp locus 67B, DmHSP23" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4463 11-Aug-17 DroID_v2017_08 "Drer\hspb7, Drer\si:dkey-1k23.3, Drer\cryaa, Drer\hspb6, Drer\cryaba, Drer\hspb8, Drer\hspb3, Drer\hspb15, Drer\hspb12, Drer\hspb11, Drer\hspb1, Drer\hspb9, Drer\cryabb, Drer\hspb2" - "Cele\hsp-16.2, Cele\hsp-16.1, Cele\hsp-17, Cele\F08H9.3, Cele\hsp-12.1, Cele\F08H9.4, Cele\hsp-16.49, Cele\hsp-16.48, Cele\hsp-12.3, Cele\ZK1128.7, Cele\hsp-43, Cele\hsp-12.2, Cele\hsp-16.41, Cele\hsp-16.11, Cele\hsp-12.6, Cele\Y55F3BR.6, Cele\sip-1" "Xtro\cryab, Xtro\hspb2, Xtro\hsp30e, Xtro\hspb3, Xtro\uqcrh, Xtro\hsp30d, Xtro\hspb8, Xtro\hspb1, Xtro\hspb6, Xtro\cryaa" "Mmus\Hspb2, Mmus\Hspb6, Mmus\Hspb7, Mmus\Cryab, Mmus\Hspb1, Mmus\Hspb3, Mmus\Hspb8, Mmus\Hspb9, Mmus\Cryaa" "Hsap\HSPB8, Hsap\HSPB7, Hsap\HSPB6, Hsap\HSPB1, Hsap\HSPB9, Hsap\CRYAB, Hsap\CRYAA, Hsap\LOC102724652, Hsap\HSPB2, Hsap\HSPB3" " larval stage | first instar , larval stage , pupal stage | early , prepupal stage , embryonic stage | early " organism

" larval stage | third instar , pupal stage , embryonic stage " "viable,cold stress response defective" "embryonic/larval heart | P-stage,mitochondrion | P-stage,sarcomere | P-stage" FBgn0043476 l(3)66EFj lethal (3) 66EFj http://flybase.org/reports/FBgn0043476 gene - - - l(3)66EFj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014469 Cyp4e2 Cytochrome P450-4e2 http://flybase.org/reports/FBgn0014469 - protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" endomembrane system ; GO:0012505 | inferred from direct assay "4e2, CYP4E2, P450, P-450, Cyt-P450-4E2, CG2060, Cyp4e2, CyP4e2, Cyp4E2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG2060 11-Aug-17 DroID_v2017_08 "Drer\cyp26c1, Drer\cyp19a1b, Drer\cyp46a1.1, Drer\cyp19a1a, Drer\cyp26b1, Drer\LOC100329425, Drer\cyp3c3, Drer\cyp3c2, Drer\cyp3c4, Drer\cyp46a1.2, Drer\cyp46a1.4, Drer\cyp20a1, Drer\cyp26a1, Drer\cyp4f3, Drer\cyp4v7, Drer\cyp3a65, Drer\cyp46a1.3, Drer\cyp3c1, Drer\cyp4v8, Drer\cyp4t8" "Scer\ERG5, Scer\DIT2" "Cele\cyp-31A3, Cele\cyp-13A3, Cele\cyp-13A8, Cele\cyp-37B1, Cele\cyp-13A11, Cele\cyp-13A7, Cele\cyp-13A12, Cele\cyp-32B1, Cele\cyp-42A1, Cele\cyp-25A2, Cele\cyp-32A1, Cele\cyp-29A4, Cele\cyp-29A3, Cele\cyp-13A10, Cele\cyp-37A1, Cele\cyp-25A4, Cele\cyp-25A1, Cele\cyp-25A3, Cele\cyp-13A5, Cele\cyp-29A2, Cele\cyp-13A1, Cele\cyp-31A5, Cele\cyp-31A2, Cele\cyp-13A4" "Xtro\cyp4v2, Xtro\cyp4f22, Xtro\mgc108213, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\cyp26a1, Xtro\LOC100488227, Xtro\cyp4f2, Xtro\cyp19a1, Xtro\cyp4b1, Xtro\LOC100487918, Xtro\cyp20a1, Xtro\cyp26b1" "Mmus\Cyp26b1, Mmus\Cyp3a41b, Mmus\Cyp4f39, Mmus\Cyp19a1, Mmus\Cyp4f15, Mmus\Cyp4f18, Mmus\Cyp4a10, Mmus\Cyp26a1, Mmus\Cyp4f14, Mmus\Cyp4f37, Mmus\Cyp3a16, Mmus\Cyp20a1, Mmus\Cyp3a25, Mmus\Cyp3a41a, Mmus\Cyp26c1, Mmus\Cyp4f16, Mmus\Cyp4f40, Mmus\Cyp4a31, Mmus\Cyp4a32, Mmus\Cyp46a1, Mmus\Cyp4a29, Mmus\Cyp4f13, Mmus\Cyp4v3, Mmus\Cyp4x1, Mmus\Cyp3a59, Mmus\Cyp4a12a, Mmus\Cyp4f17, Mmus\Cyp4a14, Mmus\Cyp3a44, Mmus\Cyp4b1, Mmus\Cyp3a13, Mmus\Cyp4a12b, Mmus\Cyp4a30b, Mmus\Cyp3a57, Mmus\Cyp3a11" "Hsap\CYP4X1, Hsap\CYP4A22, Hsap\CYP4F8, Hsap\CYP4F11, Hsap\CYP4F22, Hsap\CYP19A1, Hsap\CYP26A1, Hsap\CYP26B1, Hsap\CYP3A43, Hsap\CYP4F12, Hsap\CYP4F3, Hsap\CYP20A1, Hsap\CYP4F2, Hsap\CYP26C1, Hsap\CYP3A7, Hsap\CYP3A4, Hsap\CYP4A11, Hsap\CYP4V2, Hsap\CYP4Z1, Hsap\CYP46A1, Hsap\CYP3A5, Hsap\CYP4B1" "viable,fertile,partially lethal - majority die,some die during pupal stage,lethal" FBgn0069211 hyp-Xh hyp-Xh http://flybase.org/reports/FBgn0069211 gene - - - "hyp[Xh], hyp-Xh" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039849 CG11334 - http://flybase.org/reports/FBgn0039849 protein_coding_gene S-methyl-5-thioribose-1-phosphate isomerase activity ; GO:0046523 | inferred from biological aspect of ancestor with PANTHER:PTN002460138 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx L-methionine biosynthetic process from methylthioadenosine ; GO:0019509 | inferred from biological aspect of ancestor with PANTHER:PTN002460138 - CG11334 "IPR000649:Initiation factor 2B-related, IPR011559:Initiation factor 2B alpha/beta/delta, IPR005251:Methylthioribose-1-phosphate isomerase, IPR027363:Methylthioribose-1-phosphate isomerase-like, N-terminal domain" CG11334 11-Aug-17 DroID_v2017_08 Drer\mri1 Scer\MRI1 Cele\C01G10.9 Xtro\mri1 Mmus\Mri1 Hsap\MRI1 viable FBgn0266879 CR45340 - http://flybase.org/reports/FBgn0266879 non_protein_coding_gene - - - CR45340 - CR45340 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039266 CG11791 - http://flybase.org/reports/FBgn0039266 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11791 - CG11791 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032034 Rcd4 Reduction in Cnn dots 4 http://flybase.org/reports/FBgn0032034 protein_coding_gene - centriole replication ; GO:0007099 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay "BcDNA:SD16838, Rcd4, CG17295" "IPR029135:Protein phosphatase 1 regulatory subunit 35, C-terminal" CG17295 11-Aug-17 DroID_v2017_08 - - - - - - "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0065869 l(2)SH0260 lethal (2) SH0260 http://flybase.org/reports/FBgn0065869 gene - - - "l(2)SH0260, l(2)SH2 0260" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267327 Acp33A Accessory gland-specific peptide 33A http://flybase.org/reports/FBgn0267327 protein_coding_gene hormone activity ; GO:0005179 | non-traceable author statement "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of female receptivity, post-mating ; GO:0045434 | non-traceable author statement" extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | traceable author statement extracellular space ; GO:0005615 | inferred from sequence model "CG15841, CG6555, Acp33A, Acp33a, CG32952-A, CG32952" - CG6555 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male " male accessory gland main cell

, male accessory gland

" FBgn0259285 EP-800 - http://flybase.org/reports/FBgn0259285 gene - - - EP-800 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin,chaeta" FBgn0050428 CG30428 - http://flybase.org/reports/FBgn0050428 protein_coding_gene - apoptotic process ; GO:0006915 | inferred from electronic annotation with InterPro:IPR026753 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026753 "BcDNA:SD21514, CG30428" "IPR026753:Nuclear apoptosis-inducing factor 1, IPR028002:Myb/SANT-like DNA-binding domain" CG30428 11-Aug-17 DroID_v2017_08 "Drer\zgc:153990, Drer\naif1, Drer\zgc:113149, Drer\si:ch211-261d7.3" - - - Mmus\Naif1 Hsap\NAIF1 viable FBgn0266474 pistachio-26F pistachio at 26F http://flybase.org/reports/FBgn0266474 gene - - - "pistachio-26F, pistachio" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "egg chamber,cell non-autonomous,somatic clone,oocyte,germline clone" FBgn0044074 E(rst)I2 E(rst)I2 http://flybase.org/reports/FBgn0044074 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "I2, E(rst)I2" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0044092 E(rst)D19 E(rst)D19 http://flybase.org/reports/FBgn0044092 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D19, E(rst)D19" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "eye,cone cell,primary pigment cell,ectopic" FBgn0045064 bwa brain washing http://flybase.org/reports/FBgn0045064 protein_coding_gene ceramidase activity ; GO:0017040 | NOT inferred from mutant phenotype ceramidase activity ; GO:0017040 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 ceramidase activity ; GO:0017040 | inferred from direct assay brain development ; GO:0007420 | NOT inferred from mutant phenotype ceramide catabolic process ; GO:0046514 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 ceramide catabolic process ; GO:0046514 | inferred from direct assay regulation of lipid metabolic process ; GO:0019216 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 brain development ; GO:0007420 | inferred from mutant phenotype sphingolipid metabolic process ; GO:0006665 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008901 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 "CG13969, 38B.6, bwa, dacer" IPR008901:Ceramidase CG13969 11-Aug-17 DroID_v2017_08 "Drer\acer2, Drer\acer3, Drer\acer1" "Scer\YPC1, Scer\YDC1" Cele\W02F12.2 "Xtro\acer2, Xtro\acer3, Xtro\acer1" "Mmus\Acer1, Mmus\Acer3, Mmus\Acer2" "Hsap\ACER3, Hsap\ACER1, Hsap\ACER2" "viable,fertile,developmental rate defective,long lived,oxidative stress response defective" "mushroom body beta-lobe,adult mushroom body beta'-lobe,ellipsoid body" FBgn0037028 CG3618 - http://flybase.org/reports/FBgn0037028 protein_coding_gene - cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype - "GYCb100B, CG3618" IPR015943:WD40/YVTN repeat-like-containing domain CG3618 11-Aug-17 DroID_v2017_08 "Drer\fam234a, Drer\fam234b" - - Xtro\fam234a "Mmus\Fam234a, Mmus\Fam234b" "Hsap\FAM234B, Hsap\FAM234A" "viable,fertile" FBgn0062594 Mod(var)1540 Mod(var)1540 http://flybase.org/reports/FBgn0062594 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1540, Mod(var)1540" - - 11-Aug-17 DroID_v2017_08 - - - - - - suppressor of variegation FBgn0022754 amputee amputee http://flybase.org/reports/FBgn0022754 - gene - - - amputee - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,femur" FBgn0032072 CG9483 - http://flybase.org/reports/FBgn0032072 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.161, CG9483" - CG9483 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0040281 Aplip1 APP-like protein interacting protein 1 http://flybase.org/reports/FBgn0040281 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from physical interaction with hep MAP-kinase scaffold activity ; GO:0005078 | inferred from physical interaction with UniProtKB:Q23977 kinesin binding ; GO:0019894 | inferred from physical interaction with Klc JUN kinase binding ; GO:0008432 | NOT inferred from sequence alignment with MGI:MGI:1309464 inferred from sequence alignment with MGI:MGI:1926555 inferred from physical interaction with bsk protein binding ; GO:0005515 | inferred from physical interaction with Appl neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype retrograde synaptic vesicle transport ; GO:0048491 | inferred from mutant phenotype axonal transport of mitochondrion ; GO:0019896 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from sequence alignment with MGI:MGI:1309464 inferred from sequence alignment with MGI:MGI:1926555 anterograde synaptic vesicle transport ; GO:0048490 | inferred from mutant phenotype regulation of JNK cascade ; GO:0046328 | inferred from physical interaction with hep regulation of JNK cascade ; GO:0046328 | inferred from sequence or structural similarity with UniProtKB:Q9WVI9 axon ; GO:0030424 | inferred from direct assay "Jip1/2, APLIP1, aplip1, SP512, CG1200, dp1, ek4, E(Khc)ek4, EK4, Ek4, Aplip1, JIP1, jip1, aplilp1" "IPR001452:SH3 domain, IPR006020:PTB/PI domain, IPR011993:PH domain-like" CG1200 11-Aug-17 DroID_v2017_08 "Drer\mapk8ip1, Drer\mapk8ip2, Drer\mapk8ip1" - Cele\jip-1 "Xtro\mapk8ip1, Xtro\mapk8ip2" "Mmus\Mapk8ip2, Mmus\Mapk8ip1" "Hsap\MAPK8IP2, Hsap\MAPK8IP1" " larval stage--adult stage , adult stage , embryonic stage | mid-late , embryonic stage | late " " head

, embryonic central nervous system

, embryonic brain

" "viable,neuroanatomy defective,paralytic,fertile,posterior,lethal" "NMJ bouton,NMJ bouton | larval stage,axon,mitochondrion,axonFpa2),axonD42" FBgn0000954 fs(2)E1 female sterile (2) E1 http://flybase.org/reports/FBgn0000954 - gene - - - "fs2.1, fs(2)E1" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg,gonad,dorsal appendage" FBgn0011208 bob bobble http://flybase.org/reports/FBgn0011208 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "ms(3)06208, bob" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile,male fertile,male sterile,recessive,partially lethal - majority die,meiotic cell cycle defective,lethal,female sterile,germline clone" "Nebenkern,karyosome,germline clone,egg chamber" FBgn0003926 snRNA:U3:22A small nuclear RNA U3 at 22A http://flybase.org/reports/FBgn0003926 "FBgn0003925, FBgn0051927" snRNA_gene - - - "snRNA[[2]], K7, snRNA:U3, snRNA3, snRNA2, U3snRNA22A, CR31927, U3snRNA, snRNA:U3:22A" - CR31927 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263024 CG43319 - http://flybase.org/reports/FBgn0263024 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG43319, CG12879" - CG43319 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034957 CG3121 - http://flybase.org/reports/FBgn0034957 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "anon-WO0140519.109, CG3121" IPR006802:Radial spokehead-like protein CG3121 11-Aug-17 DroID_v2017_08 Drer\rsph4a - - Xtro\rsph6a "Mmus\Rsph6a, Mmus\Rsph4a" "Hsap\RSPH6A, Hsap\RSPH4A" viable FBgn0034976 CG4049 - http://flybase.org/reports/FBgn0034976 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 - - "BEST:LD04705, CG4049, Arip4" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain" CG4049 11-Aug-17 DroID_v2017_08 "Drer\rad54l2, Drer\atrx" Scer\RAD54 "Cele\rad-26, Cele\xnp-1" "Xtro\atrx, Xtro\rad54l2" "Mmus\Atrx, Mmus\Rad54l2" Hsap\RAD54L2 viable FBgn0050200 tRNA:Ala-CGC-1-3 transfer RNA:Alanine-CGC 1-3 http://flybase.org/reports/FBgn0050200 tRNA_gene GCG codon-amino acid adaptor activity ; GO:0033456 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033456 cytosol ; GO:0005829 | inferred by curator from GO:0033456 "CR30200, AE002575.trna8-AlaCGC, tRNA:A:CGC:AE002575-c, tRNA[[Ala]], chr2R.trna52-AlaCGC, tRNA-Ala-CGC-1-3, tRNA:Ala-CGC-1-3, tRNA:CR30200, GCG" - CR30200 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039471 CG6295 - http://flybase.org/reports/FBgn0039471 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG6295, DmelL6" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6295 11-Aug-17 DroID_v2017_08 "Drer\pla1a, Drer\lipca, Drer\lpl, Drer\LOC101884800, Drer\LOC100331214, Drer\lipg, Drer\lipia, Drer\lipib" - - "Xtro\lipg, Xtro\lpl" "Mmus\Pnliprp2, Mmus\Lipi, Mmus\Pnliprp1, Mmus\Pnlip, Mmus\Liph, Mmus\Lpl, Mmus\Lipg, Mmus\Pla1a, Mmus\Lipc" "Hsap\LIPC, Hsap\LIPH, Hsap\PNLIPRP3, Hsap\PNLIPRP2, Hsap\PLA1A, Hsap\LIPI, Hsap\PNLIP, Hsap\PNLIPRP1, Hsap\LIPG, Hsap\LPL" viable DRSC16012 K -0.112804712 0.279279894 -0.369200931 0.283664843 1.236918231 2.104315067 FBgn0085544 CG40955 - http://flybase.org/reports/FBgn0085544 protein_coding_gene - - - CG40955 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029712 CG15912 - http://flybase.org/reports/FBgn0029712 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR006439 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 - "CG15912, 24639695" "IPR006439:HAD hydrolase, subfamily IA, IPR011949:HAD-superfamily hydrolase, subfamily IA, REG-2-like, IPR023214:HAD-like domain" CG15912 11-Aug-17 DroID_v2017_08 "Drer\hdhd3, Drer\nanp, Drer\ephx2" Scer\YMR130W Cele\K01G5.10 "Xtro\hdhd3, Xtro\nanp, Xtro\ephx2, Xtro\acad10" "Mmus\Nanp, Mmus\Hdhd3, Mmus\Acad10, Mmus\Ephx2" "Hsap\NANP, Hsap\EPHX2, Hsap\ACAD10, Hsap\HDHD3" viable FBgn0038873 CG5892 - http://flybase.org/reports/FBgn0038873 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG5892 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG5892 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-31, Cele\oac-39, Cele\rhy-1, Cele\oac-5, Cele\oac-46, Cele\oac-53, Cele\oac-32, Cele\oac-50, Cele\ndg-4, Cele\oac-3, Cele\nrf-6, Cele\oac-14, Cele\oac-7, Cele\oac-55, Cele\oac-20, Cele\oac-6, Cele\oac-54, Cele\oac-9" Xtro\LOC101732251 Mmus\Oacyl - "viable,fertile" FBgn0015849 anon-10Cb anon-10Cb http://flybase.org/reports/FBgn0015849 - gene - - - anon-10Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261389 p1130 - http://flybase.org/reports/FBgn0261389 gene - - - p1130 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,long lived,dominant" FBgn0033875 CG6357 - http://flybase.org/reports/FBgn0033875 protein_coding_gene cysteine-type peptidase activity ; GO:0008234 | inferred from electronic annotation with InterPro:IPR013128 - - CG6357 "IPR013201:Cathepsin propeptide inhibitor domain (I29), IPR013128:Peptidase C1A" CG6357 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-267n13.1, Drer\ctsll, Drer\MGC174155, Drer\ctsl.1, Drer\LOC100536033, Drer\ctss2.1, Drer\ctsba, Drer\ctsk, Drer\ctsc, Drer\ctsh, Drer\ctss2.2, Drer\si:dkey-269i1.4, Drer\ctsbb, Drer\si:dkey-239j18.2, Drer\si:dkey-183k8.2, Drer\LOC100333521, Drer\ctslb, Drer\ctsz, Drer\zgc:174855, Drer\cts12, Drer\zgc:174153, Drer\wu:fa26c03, Drer\ctsla, Drer\si:dkey-239j18.3, Drer\si:dkey-228a15.1, Drer\ctss1, Drer\zgc:103438, Drer\zgc:110239" - - "Xtro\ctsl, Xtro\ctsv, Xtro\ctsb, Xtro\LOC100490139, Xtro\ctsz, Xtro\ctss, Xtro\LOC100498238, Xtro\ctsc, Xtro\ctsh" "Mmus\Cts3, Mmus\Ctsb, Mmus\Ctsr, Mmus\Tpbpa, Mmus\Ctsk, Mmus\Ctsz, Mmus\Cts8, Mmus\Ctsm, Mmus\Ctsq, Mmus\4930486L24Rik, Mmus\Ctsh, Mmus\Ctss, Mmus\Cts6, Mmus\Ctsc, Mmus\Ctsl, Mmus\Ctsll3, Mmus\Ctsj, Mmus\Cts7, Mmus\Ctla2b, Mmus\BC051665, Mmus\Tpbpb, Mmus\Ctla2a" "Hsap\CTSZ, Hsap\CTSB, Hsap\CTSC, Hsap\CTSH, Hsap\CTSL, Hsap\CTSV, Hsap\CTSK, Hsap\CTSS" viable FBgn0022318 l(1)B8.5 lethal (1) B8.5 http://flybase.org/reports/FBgn0022318 - gene - - - "B8.5, l(1)B8.5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040291 Roc1b Regulator of cullins 1b http://flybase.org/reports/FBgn0040291 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR024766 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay cullin family protein binding ; GO:0097602 | inferred from physical interaction with Cul3 zinc ion binding ; GO:0008270 | inferred from sequence model cullin family protein binding ; GO:0097602 | inferred from physical interaction with UniProtKB:Q8IP45" cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with UniProtKB:Q9W5E1 protein ubiquitination ; GO:0016567 | inferred from direct assay flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from direct assay activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from genetic interaction with Cul3 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9W5E1 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with UniProtKB:Q9W5E1 Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from direct assay "ROC1b, CG16988, ROC2, ROC1B, dRoc1b, BcDNA:AT21612, Roc1b, Roc, roc1b" "IPR001841:Zinc finger, RING-type, IPR024766:Zinc finger, RING-H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG16988 11-Aug-17 DroID_v2017_08 "Drer\rbx1, Drer\rnf7" Scer\HRT1 "Cele\rbx-2, Cele\rbx-1" Xtro\rnf7 "Mmus\Rbx1, Mmus\Rnf7" "Hsap\RBX1, Hsap\RNF7" " embryonic stage -- adult stage , larval stage " " organism

, dorsal mesothoracic disc

ubiquitous " "viable,male sterile,male semi-sterile,increased cell death,somatic clone" "spermatozoon,spermatid" FBgn0010806 l(3)03644 lethal (3) 03644 http://flybase.org/reports/FBgn0010806 - gene - - - l(3)03644 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0060564 l(3)S096516b lethal (3) S096516b http://flybase.org/reports/FBgn0060564 gene - - - "0965/16, l(3)S096516b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039980 CG18160 - http://flybase.org/reports/FBgn0039980 protein_coding_gene - - - CG18160 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024608 olfJ11 olfactory J11 http://flybase.org/reports/FBgn0024608 - gene - - - olfJ11 - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0038600 CG12364 - http://flybase.org/reports/FBgn0038600 protein_coding_gene - - - CG12364 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040018 CG12631 - http://flybase.org/reports/FBgn0040018 protein_coding_gene - - - CG12631 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031479 Prx6005 Peroxiredoxin 6005 http://flybase.org/reports/FBgn0031479 protein_coding_gene peroxiredoxin activity ; GO:0051920 | inferred from electronic annotation with InterPro:IPR019479 peroxidase activity ; GO:0004601 | inferred from direct assay "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 hydrogen peroxide catabolic process ; GO:0042744 | inferred from direct assay" cytosol ; GO:0005829 | inferred from direct assay "153181_at, CG3083, DPx6005, Prx6005, GM04269p, DPx-6005" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR024706:Peroxiredoxin, AhpC-type, IPR013766:Thioredoxin domain" CG3083 11-Aug-17 DroID_v2017_08 "Drer\prdx3, Drer\prdx2, Drer\prdx6, Drer\prdx4, Drer\prdx1" "Scer\TSA2, Scer\PRX1, Scer\TSA1" "Cele\prdx-3, Cele\prdx-2, Cele\prdx-6" Xtro\prdx6 "Mmus\Prdx2, Mmus\Prdx6b, Mmus\Prdx4, Mmus\Prdx3, Mmus\Prdx1, Mmus\Prdx6" "Hsap\PRDX1, Hsap\PRDX6, Hsap\PRDX4, Hsap\PRDX2, Hsap\PRDX3" "viable,body color defective" mesothoracic tergum FBgn0040236 c11.1 c11.1 http://flybase.org/reports/FBgn0040236 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available Golgi apparatus ; GO:0005794 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay "CG12132, c11.1, C11.1" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG12132 11-Aug-17 DroID_v2017_08 Drer\mroh1 - Cele\hpo-27 Xtro\mroh1 "Mmus\Mro, Mmus\Mroh8, Mmus\Mroh7, Mmus\Mroh4, Mmus\Mroh2a, Mmus\Mroh1, Mmus\Mroh3, Mmus\Mroh6, Mmus\Mroh2b, Mmus\Mroh9" "Hsap\MROH5, Hsap\MROH9, Hsap\MRO, Hsap\MROH2B, Hsap\MROH1, Hsap\MROH2A, Hsap\MROH7, Hsap\MROH6, Hsap\MROH8" "viable,fertile" FBgn0028213 l(3)S010102a lethal (3) S010102a http://flybase.org/reports/FBgn0028213 gene - - - "0101/02, l(3)S010102, l(3)S010102a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0029995 CG2256 - http://flybase.org/reports/FBgn0029995 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" - - CG2256 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG2256 11-Aug-17 DroID_v2017_08 "Drer\efcab1, Drer\rcvrna, Drer\hpcal4, Drer\guca1a, Drer\vsnl1b, Drer\guca1e, Drer\ncs1b, Drer\ncalda, Drer\rcvrn2, Drer\ncs1a, Drer\kcnip2, Drer\si:ch211-145b13.5, Drer\guca1c, Drer\hpca, Drer\kcnip1b, Drer\guca1g, Drer\kcnip3b, Drer\kcnip1a, Drer\usp32, Drer\si:ch211-245j22.3, Drer\kcnip4, Drer\guca1d, Drer\si:ch211-103a14.5, Drer\vsnl1a, Drer\rcvrnb, Drer\rcvrn3, Drer\hpcal1, Drer\guca1b, Drer\ncaldb" Scer\FRQ1 - "Xtro\kcnip4, Xtro\ncald, Xtro\guca1a, Xtro\ncs1, Xtro\guca1b, Xtro\kcnip1, Xtro\kcnip2, Xtro\vsnl1, Xtro\rcvrn.2, Xtro\hpcal1, Xtro\hpca, Xtro\kcnip3, Xtro\efcab1, Xtro\guca1c" "Mmus\Kcnip1, Mmus\Kcnip3, Mmus\Rcvrn, Mmus\Efcab1, Mmus\Hpcal4, Mmus\Guca1a, Mmus\Guca1b, Mmus\Kcnip4, Mmus\Hpca, Mmus\Vsnl1, Mmus\1700109H08Rik, Mmus\Ncald, Mmus\Ncs1, Mmus\Hpcal1, Mmus\Kcnip2, Mmus\Usp32" "Hsap\VSNL1, Hsap\KCNIP4, Hsap\GUCA1A, Hsap\NCS1, Hsap\RCVRN, Hsap\HPCAL1, Hsap\KCNIP3, Hsap\USP32, Hsap\HPCA, Hsap\HPCAL4, Hsap\EFCAB1, Hsap\KCNIP2, Hsap\NCALD, Hsap\KCNIP1, Hsap\GUCA1C, Hsap\GUCA1B" viable FBgn0267733 CR46064 - http://flybase.org/reports/FBgn0267733 non_protein_coding_gene - - - CR46064 - CR46064 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069098 mus327 mutagen-sensitive 327 http://flybase.org/reports/FBgn0069098 gene - - - mus327 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0004204 l(3)84Eb lethal (3) 84Eb http://flybase.org/reports/FBgn0004204 - gene - - - l(3)84Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015966 l(2)46DEd lethal (2) 46DEd http://flybase.org/reports/FBgn0015966 - gene - - - "group 8, l(2)46DEd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020563 anon-VI-C4 anon-VI-C4 http://flybase.org/reports/FBgn0020563 - gene - - - anon-VI-C4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "Bolwig organ,Bolwig nerve" FBgn0259836 Su(Ste):CR42405 Su(Ste):CR42405 http://flybase.org/reports/FBgn0259836 non_protein_coding_gene - - - "Su(Ste):CR42405, CR42405" - CR42405 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012043 Bom Bombyxin http://flybase.org/reports/FBgn0012043 - gene - - - Bom - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022165 l(2)k05614 lethal (2) k05614 http://flybase.org/reports/FBgn0022165 - gene - - - l(2)k05614 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053380 5SrRNA:CR33380 5SrRNA:CR33380 http://flybase.org/reports/FBgn0053380 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33380, 5SrRNA:CR33380" - CR33380 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061070 l(3)S018611b lethal (3) S018611b http://flybase.org/reports/FBgn0061070 gene - - - "0186/11, l(3)S018611b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262989 CR43297 - http://flybase.org/reports/FBgn0262989 non_protein_coding_gene - - - "CR43297, lincRNA.967" - CR43297 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000246 c(3)G crossover suppressor on 3 of Gowen http://flybase.org/reports/FBgn0000246 "FBgn0038362, FBgn0063641" protein_coding_gene - synaptonemal complex assembly ; GO:0007130 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | traceable author statement synaptonemal complex ; GO:0000795 | inferred from direct assay synaptonemal complex ; GO:0000795 | "C(3)G, CG17604, c(3)g, c3G, cx, c(3)G, C3G" - CG17604 11-Aug-17 DroID_v2017_08 - Scer\KAR5 - - - "Hsap\PPFIA3, Hsap\CCDC73" adult stage && O | stage S1-7 presumptive oocyte && oocyte

"meiotic cell cycle defective,female,wild-type,recessive,viable" "synaptonemal complex,synaptonemal complexnos.UTR.THsimVP16, c(3)G68,synaptonemal complexG68)nos.UTR.THsimVP16,oocyte & meiosis & nuclear chromosome,nurse cell & nuclear chromosome,germarium & nuclear chromosome,synaptonemal complexnos.UTR.THsimVP16, c(3)GCdel.UAS.PT.TZzzzFLAG,synaptonemal complexGCdel.UAS.PT.TZzzzFLAG)nos.UTR.THsimVP16,polytene chromosome chromocenter,meiotic cell cycle,meiotic metaphase I,meiotic anaphase I" FBgn0058064 ARY Aldehyde reductase Y http://flybase.org/reports/FBgn0058064 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" - "ARY, CG40064" "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG40064 11-Aug-17 DroID_v2017_08 "Drer\akr1b1, Drer\akr1a1b, Drer\zgc:56622, Drer\zgc:110782, Drer\akr1a1a, Drer\zgc:101765, Drer\si:dkey-180p18.9, Drer\zgc:110366" "Scer\ARA1, Scer\GRE3, Scer\YDL124W, Scer\GCY1, Scer\YJR096W, Scer\YPR1" "Cele\T08H10.1, Cele\C07D8.6, Cele\C56G3.2, Cele\Y39G8B.2, Cele\F53F1.2, Cele\ZC443.1, Cele\F53F1.3, Cele\K07C5.2, Cele\Y39G8B.1, Cele\C01G5.5" "Xtro\akr1d1, Xtro\LOC548351, Xtro\akr1c8p, Xtro\akr1c2, Xtro\akr1b1, Xtro\akr1a1, Xtro\akr1c1" "Mmus\Akr1c21, Mmus\Akr1b7, Mmus\Akr1c18, Mmus\Akr1a1, Mmus\Akr1c12, Mmus\Akr1d1, Mmus\Akr1cl, Mmus\Akr1c20, Mmus\Akr1b8, Mmus\Akr1b3, Mmus\Akr1e1, Mmus\Akr1b10, Mmus\Akr1c19, Mmus\Akr1c6, Mmus\Akr1c14, Mmus\Akr1c13" "Hsap\AKR1A1, Hsap\AKR1D1, Hsap\AKR1B10, Hsap\AKR1B15, Hsap\AKR1B1, Hsap\AKR1C4, Hsap\AKR1C3, Hsap\AKR1C1, Hsap\AKR1E2, Hsap\AKR1C2" FBgn0005351 streakex streakex http://flybase.org/reports/FBgn0005351 - gene - - - "streakex, stx" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,body color defective" thorax FBgn0263542 mir-4954 mir-4954 stem loop http://flybase.org/reports/FBgn0263542 miRNA_gene - - - "mir-4954, dme-mir-4954, CR43527" - CR43527 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262647 Nup160 Nucleoporin 160kD http://flybase.org/reports/FBgn0262647 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCH5 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with HGNC:18017 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000479965 mRNA export from nucleus ; GO:0006406 | inferred from sequence or structural similarity with HGNC:18017 double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN000479965 nuclear pore ; GO:0005643 | inferred from direct assay nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with HGNC:18017 "Nup160, CG4738, l(2)SH2055, l(2)SH2 2055, Nup160[mel], nup160, Nup" - CG4738 11-Aug-17 DroID_v2017_08 "Drer\nup160, Drer\LOC100535505" Scer\NUP120 Cele\npp-6 - Mmus\Nup160 Hsap\NUP160 DRSC02774 E -1.482368884 -0.124106381 -3.120267687 -1.625863346 -0.336750099 -0.341110484 FBgn0036730 qjt quijote http://flybase.org/reports/FBgn0036730 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181 SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000000745 double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000000745 Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000000745 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000745 "qjt, Quijote, CG13732, Nse2, Qjt" "IPR004181:Zinc finger, MIZ-type, IPR026846:E3 SUMO-protein ligase Nse2 (Mms21)" CG13732 11-Aug-17 DroID_v2017_08 Drer\nsmce2 Scer\MMS21 Cele\ZK1248.11 - Mmus\Nsmce2 Hsap\NSMCE2 FBgn0259259 C719.2 - http://flybase.org/reports/FBgn0259259 gene - - - C719.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing,wing vein" FBgn0261813 CR42755 - http://flybase.org/reports/FBgn0261813 non_protein_coding_gene - - - "CG42755, CR42755" - CR42755 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033440 CG10459 - http://flybase.org/reports/FBgn0033440 protein_coding_gene receptor binding ; GO:0005102 | inferred from sequence or structural similarity with MGI:MGI:1329037 negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from sequence or structural similarity with MGI:MGI:1329037 cellular_component ; GO:0005575 | no biological data available CG10459 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG10459 11-Aug-17 DroID_v2017_08 Drer\strap Scer\TIF34 - Xtro\strap Mmus\Strap "Hsap\STRAP, Hsap\FBXW9" viable DRSC05991 K -0.746006084 0.843134801 -0.254654608 0.096453341 -1.534710026 0.721058438 FBgn0011177 l(1)291-68 lethal (1) 291-68 http://flybase.org/reports/FBgn0011177 FBgn0010199 gene - - - "291-68, l(1)291-68" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259397 EP-297.2 - http://flybase.org/reports/FBgn0259397 gene - - - EP-297.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0013284 Jhbp-80 Juvenile hormone binding protein - 80kD http://flybase.org/reports/FBgn0013284 - gene - - - Jhbp-80 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000746 fs(1)A321 female sterile (1) A321 http://flybase.org/reports/FBgn0000746 - gene - - - fs(1)A321 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,visible" "egg,macrochaeta" FBgn0020821 l(3)98Di lethal (3) 98Di http://flybase.org/reports/FBgn0020821 - gene - - - "M311, l(3)98Di" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020345 Clch Chloride channel http://flybase.org/reports/FBgn0020345 - gene - - - "anon-49ABa, Clch" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001612 Grip91 Gamma-tubulin ring protein 91 http://flybase.org/reports/FBgn0001612 "FBgn0026429, FBgn0040196, FBgn0066830" protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule minus-end binding ; GO:0051011 | contributes_to inferred from direct assay gamma-tubulin binding ; GO:0043015 | inferred from direct assay microtubule nucleation ; GO:0007020 | inferred from direct assay male meiosis ; GO:0007140 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 neurogenesis ; GO:0022008 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity centrosome duplication ; GO:0051298 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 interphase microtubule nucleation by interphase microtubule organizing center ; GO:0051415 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 equatorial microtubule organizing center ; GO:0000923 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin small complex ; GO:0008275 | inferred from physical interaction with Grip84 inferred from physical interaction with γTub23C gamma-tubulin small complex ; GO:0008275 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity centrosome ; GO:0005813 | colocalizes_with inferred from direct assay mitotic spindle ; GO:0072686 | colocalizes_with inferred from direct assay "Dgrip91, Dgrips91, dd4, GCP3, dGRIP91, GRIP91, CG10988, l(1)d.deg.-4, l(1)d deg-4, l(1)d.deg.4, l(1)G0122, anon-WO03040301.197, Dgrip9, DGrip91, Grip91, Dd4, l(1)dd4" IPR007259:Gamma-tubulin complex component protein CG10988 11-Aug-17 DroID_v2017_08 "Drer\tubgcp2, Drer\tubgcp4, Drer\tubgcp6, Drer\tubgcp3" Scer\SPC98 - "Xtro\tubgcp6, Xtro\tubgcp2, Xtro\tubgcp4, Xtro\tubgcp3" "Mmus\Tubgcp3, Mmus\Tubgcp6, Mmus\Tubgcp2, Mmus\Tubgcp4" "Hsap\TUBGCP4, Hsap\TUBGCP3, Hsap\TUBGCP2, Hsap\TUBGCP6" embryonic stage "wild-type,mitotic cell cycle defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage,meiotic cell cycle defective,male limited,male sterile,cytokinesis defective,female sterile,visible,partially lethal - majority live,sterile,partially,neuroanatomy defective" "imaginal disc,cell cycle,embryonic/larval brain,mitotic cell cycle,centriole,pericentriolar material,centrosome,spermatocyte & spindle,wing,head bristle,adult thorax & macrochaeta,scutellar bristle,adult abdomen,macrochaeta,abdominal segment,ganglion mother cell,chaeta,supernumerary" DRSC20249 IE 2.294466383 0.74518313 1.954009186 0.180643229 -0.063889585 1.153351715 FBgn0261596 RpS24 Ribosomal protein S24 http://flybase.org/reports/FBgn0261596 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001976, InterPro:IPR012678 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000052028" ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "RpS24, CG3751, S24, BcDNA:RE59324, l(2)SH2053, l(2)SH2 2053, Rp S24" "IPR018098:Ribosomal S24e conserved site, IPR001976:Ribosomal protein S24e, IPR012678:Ribosomal protein L23/L15e core domain" CG3751 11-Aug-17 DroID_v2017_08 Drer\rps24 "Scer\RPS24A, Scer\RPS24B" "Cele\rps-24, Cele\T07A9.14, Cele\T26G10.3" Xtro\rps24 Mmus\Rps24 Hsap\RPS24 DRSC28412 IEK -1.681035961 -2.296661036 1.00233819 -4.236716912 4.265953391 3.233140018 FBgn0029056 l(1)G0449 lethal (1) G0449 http://flybase.org/reports/FBgn0029056 gene - - - l(1)G0449 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" third instar larva FBgn0011853 tRNA:Glu-CTC-3-6 transfer RNA:Glutamic acid-CTC 3-6 http://flybase.org/reports/FBgn0011853 "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052325, FBgn0060248" tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "AE002584.trna8-GluCTC, tRNA:E4, tRNA:E:CTC:AE002584-f, tRNA:glu4:62Ac, CR32325, tRNA:Glu, chr3L.trna8-GluCTC, tRNA:Glu-CTC-3-6, tRNA:E4:62Ac, tRNA-Glu-CTC-3-6, GAG" - CR32325 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058086 CG40086 - http://flybase.org/reports/FBgn0058086 protein_coding_gene - - - CG40086 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060688 l(3)S074510b lethal (3) S074510b http://flybase.org/reports/FBgn0060688 gene - - - "0745/10, l(3)S074510b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041175 Ubx::Hrob\Lox2 Ubx::Hrob\Lox2 http://flybase.org/reports/FBgn0041175 engineered_fusion_gene - - - Ubx::Hrob\Lox2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "leg,ectopic,antenna,haltere,wing,embryonic epidermis,abdominal 1 ventral denticle belt,Kolbchen" FBgn0014043 Su(tor)2-15 Su(tor)2-15 http://flybase.org/reports/FBgn0014043 - gene - - - Su(tor)2-15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031443 Prosbeta4R2 Proteasome beta4 subunit-related 2 http://flybase.org/reports/FBgn0031443 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 molecular_function ; GO:0003674 | no biological data available" "proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR016050" "proteasome core complex ; GO:0005839 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR016050" "anon-WO0140519.122, Prosbeta4R2, CG17302, beta4R2" "IPR001353:Proteasome, subunit alpha/beta, IPR023333:Proteasome B-type subunit, IPR016050:Proteasome beta-type subunit, conserved site, IPR029055:Nucleophile aminohydrolases, N-terminal" CG17302 11-Aug-17 DroID_v2017_08 Drer\psmb2 Scer\PRE1 Cele\pbs-4 Xtro\psmb2 Mmus\Psmb2 Hsap\PSMB2 viable FBgn0260574 MENE-GG12 - http://flybase.org/reports/FBgn0260574 gene - - - MENE-GG12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye disc,somatic clone" FBgn0265199 CG44259 - http://flybase.org/reports/FBgn0265199 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44259 - CG44259 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259641 B0432 - http://flybase.org/reports/FBgn0259641 gene - - - B0432 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0038741 CG17186 - http://flybase.org/reports/FBgn0038741 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG17186 IPR013087:Zinc finger C2H2-type CG17186 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035462 IntS10 Integrator 10 http://flybase.org/reports/FBgn0035462 protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:25548 integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:25548 "IntS10, Int10, CG1120" "IPR016024:Armadillo-type fold, IPR011990:Tetratricopeptide-like helical domain, IPR026164:Integrator complex subunit 10" CG1120 11-Aug-17 DroID_v2017_08 Drer\ints10 - "Cele\srh-166, Cele\srh-251, Cele\srh-234, Cele\srh-233, Cele\srh-194, Cele\srh-69, Cele\srh-258, Cele\srh-292, Cele\srh-207, Cele\srh-286, Cele\srh-145, Cele\srh-217, Cele\srh-236, Cele\srh-135, Cele\srh-243, Cele\srh-287, Cele\srh-248, Cele\srh-223, Cele\srh-281, Cele\srh-147, Cele\srh-208, Cele\srh-219, Cele\srh-195, Cele\srh-170, Cele\srh-192, Cele\srh-277, Cele\srh-308, Cele\srh-142, Cele\srh-199, Cele\srh-289, Cele\srh-204, Cele\srh-215, Cele\srh-201, Cele\srh-187, Cele\srh-214, Cele\srh-179, Cele\srh-216, Cele\srh-67, Cele\srh-133, Cele\srh-244, Cele\srh-212, Cele\srh-132, Cele\srh-257, Cele\srh-265, Cele\srh-206, Cele\srh-274, Cele\srh-235, Cele\srh-295, Cele\srh-134, Cele\srh-182, Cele\srh-246" Xtro\ints10 Mmus\Ints10 Hsap\INTS10 "viable,visible" trichogen cell FBgn0085157 l(3)S000718 l(3)S000718 http://flybase.org/reports/FBgn0085157 gene - - - l(3)S000718 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034127 CG7848 - http://flybase.org/reports/FBgn0034127 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NAD+) activity ; GO:0004471 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:0004473 | inferred from biological aspect of ancestor with PANTHER:PTN000601052" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302 pyruvate metabolic process ; GO:0006090 | inferred from biological aspect of ancestor with PANTHER:PTN000601050 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000601050" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001157886 CG7848 "IPR001891:Malic oxidoreductase, IPR012301:Malic enzyme, N-terminal domain, IPR012302:Malic enzyme, NAD-binding, IPR016040:NAD(P)-binding domain" CG7848 11-Aug-17 DroID_v2017_08 "Drer\me2, Drer\me3, Drer\me1, Drer\LOC101882012" Scer\MAE1 Cele\men-1 "Xtro\me2, Xtro\me3" "Mmus\Me3, Mmus\Me1, Mmus\Me2" "Hsap\ME3, Hsap\ME1, Hsap\ME2" FBgn0267983 CR46250 - http://flybase.org/reports/FBgn0267983 non_protein_coding_gene - - - CR46250 - CR46250 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262200 mir-962 mir-962 stem loop http://flybase.org/reports/FBgn0262200 miRNA_gene - "regulation of feeding behavior ; GO:0060259 | inferred from genetic interaction with mir-959, mir-960, mir-961 immune response ; GO:0006955 | inferred from genetic interaction with mir-959, mir-960, mir-961" - "dme-mir-962, 962, mir-962, CR42907, miR-962" - CR42907 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266853 CR45314 - http://flybase.org/reports/FBgn0266853 non_protein_coding_gene - - - CR45314 - CR45314 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0285926 Imp IGF-II mRNA-binding protein http://flybase.org/reports/FBgn0285926 protein_coding_gene mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay "nervous system development ; GO:0007399 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011|GO:0071013 spermatogenesis ; GO:0007283 | inferred from expression pattern neuron remodeling ; GO:0016322 | inferred from mutant phenotype positive regulation of axon regeneration ; GO:0048680 | inferred from mutant phenotype carbohydrate metabolic process ; GO:0005975 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "imp, Imp, IMP, ORE-9, CG1691, dIMP, cg1691, l(1)G0072, anon-EST:fe2B3, IGF-II, anon-WO0140519.39, IMP-1, MRE11, mre11, IGF2BP1, FGC026A04" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR000504:RNA recognition motif domain" CG1691 11-Aug-17 DroID_v2017_08 "Drer\igf2bp1, Drer\igf2bp2a, Drer\igf2bp2b, Drer\igf2bp3" - "Cele\zbp-1, Cele\M01A10.1" Xtro\igf2bp3 "Mmus\Igf2bp2, Mmus\Igf2bp1, Mmus\Igf2bp3" "Hsap\IGF2BP1, Hsap\IGF2BP2, Hsap\IGF2BP3" FBgn0087015 l(3)61Dc lethal (3) 61Dc http://flybase.org/reports/FBgn0087015 gene - - - l(3)61Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal" FBgn0065097 snmRNA:357 small non-messenger RNA 357 http://flybase.org/reports/FBgn0065097 non_protein_coding_gene - - - "Dm-357, CR33659, snmRNA:357" - CR33659 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264992 CR44143 - http://flybase.org/reports/FBgn0264992 non_protein_coding_gene - - - CR44143 - CR44143 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061361 CG33786 - http://flybase.org/reports/FBgn0061361 protein_coding_gene double-stranded RNA binding ; GO:0003725 | inferred from electronic annotation with InterPro:IPR006070 tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 nucleotidyltransferase activity ; GO:0016779 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 tRNA threonylcarbamoyladenosine modification ; GO:0002949 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 regulation of translational fidelity ; GO:0006450 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 "CG33005, CG10438b, CG10438, CG33005-ORFB, CG33786, Dromel_CG33786_FBtr0091786_mORF, CG33005ORFB, sua5" "IPR006070:YrdC-like domain, IPR017945:DHBP synthase RibB-like alpha/beta domain" CG33786 11-Aug-17 DroID_v2017_08 "Drer\yrdc, Drer\si:ch211-153b23.4, Drer\polr3k" "Scer\SUA5, Scer\RPC11" "Cele\rpc-11, Cele\Y48C3A.18" "Xtro\polr3k, Xtro\yrdc" "Mmus\Yrdc, Mmus\Polr3k" "Hsap\POLR3K, Hsap\YRDC" FBgn0034304 CG5742 - http://flybase.org/reports/FBgn0034304 protein_coding_gene receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000966452 neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of receptor biosynthetic process ; GO:0010869 | inferred from biological aspect of ancestor with PANTHER:PTN000966452 protein retention in ER lumen ; GO:0006621 | inferred from biological aspect of ancestor with PANTHER:PTN000966452 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000966452 CG5742 "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR021832:Ankyrin repeat domain-containing protein 13" CG5742 11-Aug-17 DroID_v2017_08 "Drer\ankrd13c, Drer\ankrd13d, Drer\ankrd13b, Drer\ankrd13a" - Cele\C01F1.6 "Xtro\ankrd13c, Xtro\ankrd13b, Xtro\ankrd13a" "Mmus\Ankrd13c, Mmus\Ankrd13b, Mmus\Ankrd13a, Mmus\Ankrd13d" "Hsap\ANKRD13B, Hsap\ANKRD13A, Hsap\ANKRD13C, Hsap\ANKRD13D" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0011222 gru gruyere http://flybase.org/reports/FBgn0011222 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - gru - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male sterile,partially lethal - majority die" Nebenkern FBgn0064187 ctu count-up http://flybase.org/reports/FBgn0064187 gene - - - ctu - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019651 su(mbm) suppressor of mushroom body miniature http://flybase.org/reports/FBgn0019651 - gene - - - su(mbm) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025620 CG13360 - http://flybase.org/reports/FBgn0025620 - protein_coding_gene - - - "EG:34F3.5, CG13360" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG13360 11-Aug-17 DroID_v2017_08 - - "Cele\C29F7.2, Cele\T16G1.3, Cele\nhr-246, Cele\C29F7.1, Cele\dhs-27, Cele\H06H21.8" - - - viable FBgn0267053 CR45497 - http://flybase.org/reports/FBgn0267053 pseudogene_attribute - - - CR45497 - CR45497 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034552 CG17999 - http://flybase.org/reports/FBgn0034552 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG17999 "IPR020845:AMP-binding, conserved site, IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase" CG17999 11-Aug-17 DroID_v2017_08 "Drer\acsbg1, Drer\acsf3" Scer\PCS60 "Cele\acs-9, Cele\acs-7, Cele\acs-14, Cele\acs-6, Cele\C25G6.3, Cele\mec-18, Cele\acs-10, Cele\sur-5, Cele\C32E8.6" Xtro\acsf3 "Mmus\Aacs, Mmus\Acsf3, Mmus\Acsbg1" "Hsap\ACSF3, Hsap\ACSBG1, Hsap\AACS" viable FBgn0267688 CR46024 - http://flybase.org/reports/FBgn0267688 non_protein_coding_gene - - - CR46024 - CR46024 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086704 stops slow termination of phototransduction http://flybase.org/reports/FBgn0086704 protein_coding_gene - intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001496 deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - "CG31006, CG15559, CG15558, CG15557, su(rdgB)69, stops" IPR001496:SOCS box domain CG31006 11-Aug-17 DroID_v2017_08 - - - - Mmus\Asb17 Hsap\ASB17 FBgn0046640 anon-38D.4 anon-38D.4 http://flybase.org/reports/FBgn0046640 gene - - - "38D.4, anon-38D.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002541 ld loboid http://flybase.org/reports/FBgn0002541 - gene - - - ld - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced,dominant,partially" "eye,ommatidium" FBgn0263494 CR43483 - http://flybase.org/reports/FBgn0263494 pseudogene_attribute - - - CR43483 - CR43483 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032519 CG16957 - http://flybase.org/reports/FBgn0032519 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000031653 heme binding ; GO:0020037 | inferred from sequence or structural similarity with SGD:S000006091 biological_process ; GO:0008150 | no biological data available endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000006091 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 CG16957 IPR001199:Cytochrome b5-like heme/steroid binding domain CG16957 11-Aug-17 DroID_v2017_08 "Drer\pgrmc2, Drer\pgrmc1, Drer\nenf" Scer\DAP1 Cele\vem-1 "Xtro\nenf, Xtro\pgrmc1, Xtro\pgrmc2" "Mmus\Nenf, Mmus\Pgrmc1, Mmus\Pgrmc2" "Hsap\NENF, Hsap\PGRMC1, Hsap\PGRMC2" "viable,fertile" FBgn0029924 CG4586 - http://flybase.org/reports/FBgn0029924 protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012258, InterPro:IPR013786 acyl-CoA oxidase activity ; GO:0003997 | inferred from sequence or structural similarity with HGNC:119" fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:119 "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:119,HGNC:120 inferred from sequence model" CG4586 "IPR002655:Acyl-CoA oxidase, C-terminal, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR012258:Acyl-CoA oxidase, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR029320:Acyl-coenzyme A oxidase, N-terminal" CG4586 11-Aug-17 DroID_v2017_08 "Drer\acox3, Drer\acox1" Scer\POX1 "Cele\acox-5, Cele\acox-1, Cele\acox-3, Cele\F59F4.1, Cele\acdh-13, Cele\acox-4, Cele\acox-2" "Xtro\acox1, Xtro\acox2" "Mmus\Acox2, Mmus\Acox1, Mmus\Acox3" "Hsap\ACOX2, Hsap\ACOX1, Hsap\ACOX3" "viable,fertile" FBgn0086068 snoRNA:Or-CD12 - http://flybase.org/reports/FBgn0086068 snoRNA_gene - - - "snoRNA:Or-CD12, orphan CD12, DmOr_cd12(DmU24), CR34697, DmU24, dM_28s.017" - CR34697 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063413 l(3)3450-J lethal (3) 3450-J http://flybase.org/reports/FBgn0063413 gene - - - l(3)3450-J - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015738 I-55 screen I - clone 55 http://flybase.org/reports/FBgn0015738 - gene - - - I-55 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065317 l(2)SH1924 lethal (2) SH1924 http://flybase.org/reports/FBgn0065317 gene - - - "l(2)SH1924, l(2)SH2 1924" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065641 l(2)SH0759 lethal (2) SH0759 http://flybase.org/reports/FBgn0065641 gene - - - "l(2)SH0759, l(2)SH2 0759" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014922 anon-72ABf anon-72ABf http://flybase.org/reports/FBgn0014922 - gene - - - anon-72ABf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032001 CG8360 - http://flybase.org/reports/FBgn0032001 protein_coding_gene cytidine deaminase activity ; GO:0004126 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 cytidine deamination ; GO:0009972 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 "BcDNA:LP03131, CG8360" "IPR002125:Cytidine and deoxycytidylate deaminases, zinc-binding, IPR006262:Cytidine deaminase, homotetrameric, IPR016193:Cytidine deaminase-like" CG8360 11-Aug-17 DroID_v2017_08 "Drer\zgc:103586, Drer\cda" Scer\CDD1 "Cele\cdd-1, Cele\cdd-2" - "Mmus\Cda, Mmus\Gm15114, Mmus\Maged2, Mmus\Maged1, Mmus\Tro" "Hsap\MAGED2, Hsap\CDA, Hsap\MAGED4B, Hsap\MAGED4, Hsap\MAGED1, Hsap\TRO" viable DRSC03085 K -0.227651764 -0.449098085 1.438443853 0.174876159 0.90255534 1.700501246 FBgn0028202 l(3)S018405 lethal (3) S018405 http://flybase.org/reports/FBgn0028202 gene - - - "0184/05, l(3)S018405" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage" FBgn0000380 cs creased http://flybase.org/reports/FBgn0000380 - gene - - - cs - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" "wing,1st posterior cell" FBgn0037656 CG11986 - http://flybase.org/reports/FBgn0037656 protein_coding_gene - - - CG11986 IPR003738:SOS response associated peptidase (SRAP) CG11986 11-Aug-17 DroID_v2017_08 Drer\hmces Scer\YMR114C - Xtro\hmces Mmus\Hmces Hsap\HMCES "viable,fertile" FBgn0022787 Hel89B Helicase 89B http://flybase.org/reports/FBgn0022787 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 ATP-dependent DNA helicase activity ; GO:0004003 | inferred from sequence or structural similarity with SGD:S000006003 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with SGD:S000006003 antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype - "BTAF1, 89B, CG4261, Hel89B, Helicase89B, Mot1, HEL89B" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR011989:Armadillo-like helical, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR016024:Armadillo-type fold, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022707:Domain of unknown function DUF3535" CG4261 11-Aug-17 DroID_v2017_08 Drer\btaf1 Scer\MOT1 Cele\btf-1 Xtro\btaf1 Mmus\Btaf1 Hsap\BTAF1 embryonic stage -- adult stage ", embryonic stage | stage >=12 , embryonic stage | early " " unfertilized egg

, longitudinal connective

,

ubiquitous , embryonic brain

, ventral nerve cord

" "visible,recessive,male sterile,partially lethal - majority die,viable" "abdominal sternite 6,male" FBgn0266441 CG45071 - http://flybase.org/reports/FBgn0266441 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "CG45071, CG6854, Polypeptide A" "IPR004210:BESS motif, IPR006578:MADF domain" CG45071 11-Aug-17 DroID_v2017_08 - "Scer\URA8, Scer\URA7" - - Mmus\Ctps Hsap\CTPS1 FBgn0043806 CG32032 - http://flybase.org/reports/FBgn0043806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH25183, BcDNA:RH42907, CG32032" IPR012674:Calycin CG32032 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023078 h::sna h::sna http://flybase.org/reports/FBgn0023078 - engineered_fusion_gene - - - h::sna - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female" FBgn0065563 l(2)SH0983 lethal (2) SH0983 http://flybase.org/reports/FBgn0065563 gene - - - "l(2)SH0983, l(2)SH2 0983, SH0983" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005697 l(3)88Ac lethal (3) 88Ac http://flybase.org/reports/FBgn0005697 - gene - - - l(3)88Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive,cold sensitive" FBgn0028306 l(1)G0375 lethal (1) G0375 http://flybase.org/reports/FBgn0028306 gene - - - l(1)G0375 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,male,female,recessive" FBgn0027133 l(3)99Ba lethal (3) 99Ba http://flybase.org/reports/FBgn0027133 - gene - - - l(3)99Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020810 mei-1725 mei-1725 http://flybase.org/reports/FBgn0020810 - gene - - - mei-1725 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030261 CG15203 - http://flybase.org/reports/FBgn0030261 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from biological aspect of ancestor with PANTHER:PTN002219240 extracellular space ; GO:0005615 | inferred from sequence model "144845_at, CG15203, DIGF-1" IPR029277:Single domain Von Willebrand factor type C domain CG15203 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029104 anon-21Ab anon-21Ab http://flybase.org/reports/FBgn0029104 gene - - - "X, anon-21Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042221 CG12435 - http://flybase.org/reports/FBgn0042221 protein_coding_gene - - - "CG18588, CG12435" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051145 CG31145 - http://flybase.org/reports/FBgn0051145 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with fj protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with fj inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG13820, CG13821, CG10187, CG31145" "IPR009581:FAM20, C-terminal, IPR024869:FAM20, IPR015943:WD40/YVTN repeat-like-containing domain" CG31145 11-Aug-17 DroID_v2017_08 "Drer\fam20cl, Drer\fam20cb, Drer\fam20a, Drer\fam20ca, Drer\samd7, Drer\fam20b" - Cele\H03A11.1 "Xtro\fam20c, Xtro\fam20a, Xtro\fam20b, Xtro\samd7" "Mmus\Fam20b, Mmus\Fam20a, Mmus\Samd7, Mmus\Fam20c" "Hsap\FAM20C, Hsap\FAM20A, Hsap\FAM20B, Hsap\SAMD7" viable FBgn0265882 CR44671 - http://flybase.org/reports/FBgn0265882 non_protein_coding_gene - - - "CR44671, lincRNA.607" - CR44671 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040475 SH3PX1 SH3 and PX domain containing 1 http://flybase.org/reports/FBgn0040475 protein_coding_gene "phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from sequence or structural similarity with HGNC:19245" mitotic nuclear division ; GO:0007067 | inferred from electronic annotation with InterPro:IPR014536 protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR014536 presynaptic active zone organization ; GO:1990709 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype positive regulation of neurotransmitter secretion ; GO:0001956 | inferred from mutant phenotype lamellipodium assembly ; GO:0030032 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from mutant phenotype cytoplasmic vesicle ; GO:0031410 | inferred from biological aspect of ancestor with PANTHER:PTN000831156 subsynaptic reticulum ; GO:0071212 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay presynaptic membrane ; GO:0042734 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay "DSH3PX1, p63, CG6757, SH3PX1, DSH3PX, dSH3PX1, DmSNX18, sh3px1" "IPR001452:SH3 domain, IPR001683:Phox homologous domain, IPR014536:Sorting nexin 9 subfamily, IPR019497:Sorting nexin protein, WASP-binding domain" CG6757 11-Aug-17 DroID_v2017_08 "Drer\snx18a, Drer\snx33, Drer\snx9b, Drer\snx9a, Drer\snx18b, Drer\snx1a" "Scer\SNX4, Scer\VPS5" "Cele\snx-1, Cele\lst-4, Cele\snx-6" "Xtro\snx30, Xtro\snx18, Xtro\snx1, Xtro\snx33, Xtro\snx9" "Mmus\Snx18, Mmus\Snx9, Mmus\Snx30, Mmus\Snx1, Mmus\Snx33, Mmus\Snx2" "Hsap\SNX30, Hsap\SNX9, Hsap\SNX2, Hsap\SNX1, Hsap\SNX33, Hsap\SNX18" "viable,fertile" FBgn0062664 EP3140 EP3140 http://flybase.org/reports/FBgn0062664 gene - - - "EP(3)3140, EP3140" - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "embryonic/larval central nervous system,neurite | pharate adult stage" FBgn0046681 anon-38B.23 anon-38B.23 http://flybase.org/reports/FBgn0046681 gene - - - "38B.23, anon-38B.23" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016918 ninaE::Rh2 ninaE::Rh2 http://flybase.org/reports/FBgn0016918 - engineered_fusion_gene - - - ninaE::Rh2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030623 PPYR1 Protein phosphatase Y regulator 1 http://flybase.org/reports/FBgn0030623 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "BcDNA:AT19571, PPYR1, CG15031" IPR006861:Hyaluronan/mRNA-binding protein CG15031 11-Aug-17 DroID_v2017_08 "Drer\zgc:103482, Drer\serbp1b, Drer\serbp1a" "Scer\TMA10, Scer\STF2" "Cele\K01D12.9, Cele\vig-1, Cele\ZK285.2, Cele\K01D12.10, Cele\K01D12.8, Cele\R74.2" "Xtro\serbp1, Xtro\habp4" "Mmus\Habp4, Mmus\Serbp1" "Hsap\HABP4, Hsap\SERBP1" viable FBgn0013494 l(1)9PP12 lethal (1) 9PP12 http://flybase.org/reports/FBgn0013494 - gene - - - l(1)9PP12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect" "embryo,germline clone,embryonic head" FBgn0038950 CG5382 - http://flybase.org/reports/FBgn0038950 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model dsRNA transport ; GO:0033227 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay CG5382 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5382 11-Aug-17 DroID_v2017_08 Drer\zfpl1 - Cele\Y45G12B.2 Xtro\zfpl1 Mmus\Zfpl1 Hsap\ZFPL1 FBgn0017391 l(1)15Bc lethal (1) 15Bc http://flybase.org/reports/FBgn0017391 - gene - - - l(1)15Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052232 CG32232 - http://flybase.org/reports/FBgn0052232 protein_coding_gene gamma-tubulin binding ; GO:0043015 | inferred from electronic annotation with InterPro:IPR007259 molecular_function ; GO:0003674 | no biological data available microtubule nucleation ; GO:0007020 | inferred from electronic annotation with InterPro:IPR007259 spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 microtubule organizing center ; GO:0005815 | inferred from electronic annotation with InterPro:IPR007259 CG32232 IPR007259:Gamma-tubulin complex component protein CG32232 11-Aug-17 DroID_v2017_08 "Drer\tubgcp6, Drer\tubgcp5" - Cele\droe-4 "Xtro\tubgcp5, Xtro\tubgcp6" "Mmus\Tubgcp6, Mmus\Tubgcp5" Hsap\TUBGCP5 viable FBgn0036782 CG7320 - http://flybase.org/reports/FBgn0036782 protein_coding_gene - - - CG7320 "IPR014756:Immunoglobulin E-set, IPR013788:Hemocyanin/hexamerin, IPR005204:Hemocyanin, N-terminal, IPR000896:Hemocyanin/hexamerin middle domain, IPR008922:Uncharacterised domain, di-copper centre, IPR005203:Hemocyanin, C-terminal" CG7320 11-Aug-17 DroID_v2017_08 - - "Cele\C49A9.3, Cele\F58F9.4, Cele\C49A9.2" - - - FBgn0001885 l(2)21Bb lethal (2) 21Bb http://flybase.org/reports/FBgn0001885 - gene - - - l(2)21Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036593 CG13048 - http://flybase.org/reports/FBgn0036593 protein_coding_gene - - - CG13048 - CG13048 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034294 Muc55B Mucin 55B http://flybase.org/reports/FBgn0034294 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model biological_process ; GO:0008150 | no biological data available extracellular matrix ; GO:0031012 | inferred from sequence model "Muc55B, CG5765" IPR007931:Protein of unknown function DUF725 CG5765 11-Aug-17 DroID_v2017_08 - - "Cele\F14F9.2, Cele\Y57E12B.4, Cele\F33E2.6" - Mmus\Khdc3 "Hsap\KHDC3L, Hsap\CLEC4F, Hsap\PRR21" "viable,fertile" DRSC21440 K -0.158658669 0.25873674 -0.629524309 -0.243706762 -1.566627092 -0.560463786 FBgn0037000 ZnT77C Zinc transporter 77C http://flybase.org/reports/FBgn0037000 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016323 zinc efflux transmembrane transporter activity ; GO:0022883 | inferred from direct assay response to zinc ion ; GO:0010043 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 zinc II ion transmembrane transport ; GO:0071577 | inferred from mutant phenotype detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype regulation of sequestering of zinc ion ; GO:0061088 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002524 plasma membrane ; GO:0005886 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "anon-WO0118547.435, CG5130, dZnT77C, ZnT77C, cg5130" "IPR002524:Cation efflux protein, IPR027470:Cation efflux protein, cytoplasmic domain" CG5130 11-Aug-17 DroID_v2017_08 "Drer\slc30a10, Drer\slc30a1a, Drer\LOC100002134, Drer\slc30a1b" "Scer\ZRG17, Scer\ZRC1, Scer\COT1" Cele\cdf-1 "Xtro\slc30a10, Xtro\slc30a1" "Mmus\Slc30a10, Mmus\Slc30a1" "Hsap\SLC30A10, Hsap\SLC30A1" "viable,fertile" FBgn0044331 936 936 http://flybase.org/reports/FBgn0044331 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available 936 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046212 CG15841 - http://flybase.org/reports/FBgn0046212 protein_coding_gene - - - "CG32952-B, CG32952, CG15841, cg15841" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042635 l(3)S024314b lethal (3) S024314b http://flybase.org/reports/FBgn0042635 gene - - - "l(3)024314, 0243/14, l(3)S024314, l(3)S024314b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053430 5SrRNA:CR33430 5SrRNA:CR33430 http://flybase.org/reports/FBgn0053430 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33430, 5SrRNA:CR33430" - CR33430 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267664 CR46002 - http://flybase.org/reports/FBgn0267664 non_protein_coding_gene - - - CR46002 - CR46002 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001268 intro introverted http://flybase.org/reports/FBgn0001268 - gene - - - "l(1)Q56, Q56, YT1, R9-13, 23, l(1)20Ac, l(1)19-88, intro" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,viable" head FBgn0041843 E(Sev-CycE)D50 E(Sev-CycE)D50 http://flybase.org/reports/FBgn0041843 gene - - - E(Sev-CycE)D50 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035620 CG5150 - http://flybase.org/reports/FBgn0035620 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG5150 "IPR001952:Alkaline phosphatase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG5150 11-Aug-17 DroID_v2017_08 "Drer\alpi.1, Drer\alp3, Drer\alpl, Drer\alpi.2" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1" "Mmus\Alpi, Mmus\Alpl, Mmus\Alppl2, Mmus\Akp3" "Hsap\ALPL, Hsap\ALPI, Hsap\ALPPL2, Hsap\ALPP" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0065519 l(2)SH1139 lethal (2) SH1139 http://flybase.org/reports/FBgn0065519 gene - - - "l(2)SH1139, l(2)SH2 1139" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005053 fs(1)ne6 female sterile (1) no eggs 6 http://flybase.org/reports/FBgn0005053 - gene - - - "ne6, fs(1)ne[6], fs(1)ne6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "oocyte,dorsal appendage,chorion" FBgn0060388 l(3)S134012a lethal (3) S134012a http://flybase.org/reports/FBgn0060388 gene - - - "1340/12, l(3)S134012a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039073 CG4408 - http://flybase.org/reports/FBgn0039073 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "BEST:GH09055, CG4408" "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG4408 11-Aug-17 DroID_v2017_08 "Drer\cpo, Drer\cpa5, Drer\cpa4, Drer\cpb1, Drer\cpa6, Drer\cpa1, Drer\cpa2, Drer\cpb2" Scer\ECM14 "Cele\W01A8.6, Cele\T06A4.1, Cele\ZC434.9, Cele\suro-1, Cele\Y18H1A.9, Cele\Y47G6A.19, Cele\Y59C2A.1, Cele\F02D8.4, Cele\T06A4.3" "Xtro\cpa3, Xtro\cpo, Xtro\LOC100490370, Xtro\cpa1, Xtro\cpb1, Xtro\cpb2" "Mmus\Cpa4, Mmus\Cpa5, Mmus\Cpb2, Mmus\Cpb1, Mmus\Cpa6, Mmus\Cpa2, Mmus\Cpm, Mmus\Cpa3, Mmus\Cpa1" "Hsap\CPA1, Hsap\CPO, Hsap\CPA3, Hsap\CPA6, Hsap\CPA2, Hsap\CPA4, Hsap\CPA5, Hsap\CPB1, Hsap\CPM, Hsap\CPB2" viable FBgn0000317 ck crinkled http://flybase.org/reports/FBgn0000317 "FBgn0015260, FBgn0015868, FBgn0020027, FBgn0044341" protein_coding_gene "myosin light chain binding ; GO:0032027 | inferred from physical interaction with Mlc-c motor activity ; GO:0003774 | inferred from sequence or structural similarity with NCBI_gi:613788 actin-dependent ATPase activity ; GO:0030898 | inferred from direct assay cadherin binding ; GO:0045296 | inferred from physical interaction with Cad99C ATP binding ; GO:0005524 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity with NCBI_gi:613788 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from genetic interaction with wg actin filament-based movement ; GO:0030048 | inferred from direct assay actin filament organization ; GO:0007015 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with dsh inferred from genetic interaction with fz chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with spen antennal development ; GO:0007469 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from genetic interaction with spen sensory perception of sound ; GO:0007605 | inferred from mutant phenotype follicle cell microvillus organization ; GO:0032529 | inferred from mutant phenotype microvillus ; GO:0005902 | inferred from direct assay unconventional myosin complex ; GO:0016461 | inferred from sequence or structural similarity with NCBI_gi:613788 micropyle ; GO:0070825 | inferred from direct assay myosin VII complex ; GO:0031477 | inferred from physical interaction with Mlc-c myosin complex ; GO:0016459 | inferred from sequence or structural similarity apical cortex ; GO:0045179 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay female germline ring canal outer rim ; GO:0035182 | inferred from direct assay basal cortex ; GO:0045180 | inferred from direct assay unconventional myosin complex ; GO:0016461 | inferred from sequence or structural similarity cell cortex ; GO:0005938 | inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay "CG7595, ck, myoVIIA, DmVIIa, DMyoVIIa, Dm 35B, DmVIIA, anon-35Bb, BG:DS00929.11, l(2)br27, l(2)35Ca, Mhc35BC, 53D10S, Dro35B, l35Ca, br27, D, D2, stc, l(2)07130, l(1)35Ca, ESTS:53D10S, stch, ck/MyoVIIA, MyoVIIA, DM7a, Myo7A, Myo7B" "IPR000048:IQ motif, EF-hand binding site, IPR000299:FERM domain, IPR000857:MyTH4 domain, IPR001452:SH3 domain, IPR001609:Myosin head, motor domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011993:PH domain-like" CG7595 11-Aug-17 DroID_v2017_08 "Drer\myo10l3, Drer\myo7bb, Drer\myo9ab, Drer\LOC556989, Drer\myo15b, Drer\myo7aa, Drer\myo9aa, Drer\myo15aa, Drer\si:ch73-194h10.2, Drer\myo10, Drer\myo10l1, Drer\myo7ab, Drer\myo9b, Drer\myo3b, Drer\myo15ab" "Scer\MYO2, Scer\MYO1" Cele\hum-6 "Xtro\myo10.2, Xtro\myo3b, Xtro\myo10, Xtro\myo9a, Xtro\myo3a, Xtro\myo7a" "Mmus\Myo10, Mmus\Myo15, Mmus\Myo7b, Mmus\Myo9a, Mmus\Myo9b, Mmus\Myo3a, Mmus\Myo7a, Mmus\Myo3b" "Hsap\MYO10, Hsap\MYO15A, Hsap\MYO3B, Hsap\MYO9B, Hsap\MYO7B, Hsap\MYO3A, Hsap\MYO7A, Hsap\MYO9A" "viable,fertile,auditory perception defective,visible,recessive,partially lethal - majority die,lethal,lethal - all die before end of larval stage,some die during larval stage,sterile,lethal - all die before end of embryonic stage,some die during embryonic stage" "Johnston's organ & scolopidium,Johnston's organ & dendritic cap cell,wing hair,supernumerary,dorsal fine hair,ocellar bristle,arista,ectopic,macrochaeta,microchaeta,trichogen cell,wing,male genitalia" FBgn0051644 CG31644 - http://flybase.org/reports/FBgn0051644 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from electronic annotation with InterPro:IPR004204 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT20031, CG31644" IPR004204:Cytochrome c oxidase subunit 6C CG31644 11-Aug-17 DroID_v2017_08 Drer\cox6c - "Cele\Y111B2A.2, Cele\B0035.18, Cele\F29C4.2" Xtro\LOC100489195 Mmus\Cox6c Hsap\COX6C viable FBgn0003182 Q Queer wing http://flybase.org/reports/FBgn0003182 - gene - - - Q - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,abdominal tergite marginal bristle" FBgn0283434 CG46277 - http://flybase.org/reports/FBgn0283434 protein_coding_gene - microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 "CG46277, SdicC" "IPR001680:WD40 repeat, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG46277 11-Aug-17 DroID_v2017_08 "Drer\dync1i2b, Drer\LOC103908626" - Cele\dyci-1 "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Dync1i2, Mmus\Dync1i1" "Hsap\DYNC1I2, Hsap\DYNC1I1" FBgn0264374 CR43826 - http://flybase.org/reports/FBgn0264374 non_protein_coding_gene - - - CR43826 - CR43826 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259749 mmy mummy http://flybase.org/reports/FBgn0259749 protein_coding_gene UDP-N-acetylglucosamine diphosphorylase activity ; GO:0003977 | inferred from sequence or structural similarity UDP-N-acetylglucosamine diphosphorylase activity ; GO:0003977 | inferred from mutant phenotype "open tracheal system development ; GO:0007424 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype axonal fasciculation ; GO:0007413 | inferred from mutant phenotype embryonic epithelial tube formation ; GO:0001838 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype cuticle chitin biosynthetic process ; GO:0006035 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype UDP-N-acetylglucosamine biosynthetic process ; GO:0006048 | inferred from biological aspect of ancestor with PANTHER:PTN000237224 extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000237128 "mmy, cao, CG9535, cystic, mum, LD44264, BcDNA:LD24639, cyst, cys, l(2)k13717b, anon-WO0140519.242, mummy" "IPR002618:UDPGP family, IPR029044:Nucleotide-diphospho-sugar transferases" CG9535 11-Aug-17 DroID_v2017_08 "Drer\uap1, Drer\sec61a1, Drer\uap1l1, Drer\sec61a1l" Scer\QRI1 "Cele\C36A4.4, Cele\sec-61" "Xtro\uap1, Xtro\uap1l1, Xtro\sec61a1" "Mmus\Sec61a1, Mmus\Uap1l1, Mmus\Sec61a2, Mmus\Uap1" "Hsap\UAP1L1, Hsap\UAP1, Hsap\SEC61A2, Hsap\SEC61A1" FBgn0063380 snoRNA:U31:54Eb snoRNA:U31:54Eb http://flybase.org/reports/FBgn0063380 snoRNA_gene - - - "U31snoRNA, CR32897, snoRNA:U31:54Eb" - CR32897 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067327 A23 A23 http://flybase.org/reports/FBgn0067327 gene - - - A23 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,lethal" pigment cell FBgn0015522 olf186-M olf186-M http://flybase.org/reports/FBgn0015522 - protein_coding_gene receptor binding ; GO:0005102 | inferred from electronic annotation with InterPro:IPR029325 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14489, olf186-M" IPR029325:IP3R-interacting domain CG14489 11-Aug-17 DroID_v2017_08 "Drer\tespa1, Drer\ccdc129, Drer\ssfa2" - - - "Mmus\Ccdc129, Mmus\Tespa1, Mmus\Ssfa2" "Hsap\CCDC129, Hsap\SSFA2, Hsap\TESPA1" viable FBgn0002814 ms(1)V73 male sterile (1) V73 http://flybase.org/reports/FBgn0002814 - gene - - - ms(1)V73 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0017464 TfIIH-45 Transcription factor IIH-45kD http://flybase.net/reports/FBgn0017464.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TFIIH, TfIIH" 11-Aug-17 DroID_v2017_08 FBgn0035926 CG5804 - http://flybase.org/reports/FBgn0035926 protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 - - "BcDNA:RE05521, CG5804" "IPR000582:Acyl-CoA-binding protein, ACBP, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle" CG5804 11-Aug-17 DroID_v2017_08 "Drer\dbi, Drer\mettl23, Drer\acbd6, Drer\acbd7, Drer\acbd4, Drer\zgc:92030, Drer\acbd5b, Drer\LOC103909942" Scer\ACB1 "Cele\acbp-6, Cele\acbp-3, Cele\acbp-5, Cele\maa-1, Cele\acbp-4, Cele\acbp-1" "Xtro\acbd7, Xtro\acbd5, Xtro\mettl23, Xtro\eci2, Xtro\acbd6" "Mmus\Dbi, Mmus\Acbd6, Mmus\Acbd4, Mmus\Acbd5, Mmus\Dbil5, Mmus\Acbd7, Mmus\Eci2, Mmus\Mettl23" "Hsap\ACBD4, Hsap\ECI2, Hsap\DBI, Hsap\METTL23, Hsap\ACBD6, Hsap\ACBD5, Hsap\ACBD7" viable FBgn0031550 IFT57 Intraflagellar transport 57 http://flybase.org/reports/FBgn0031550 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with MGI:MGI:1921166 regulation of apoptotic process ; GO:0042981 | inferred from sequence or structural similarity with UniProtKB:Q9NWB7 apoptotic process ; GO:0006915 | inferred from sequence or structural similarity with UniProtKB:Q9NWB7 cilium assembly ; GO:0060271 | inferred from sequence model intraciliary transport ; GO:0042073 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from sequence or structural similarity with UniProtKB:Q9NWB7 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 intraciliary transport particle B ; GO:0030992 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 ciliary basal body ; GO:0036064 | inferred from sequence or structural similarity with UniProtKB:Q8BXG3 cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:1921166 cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:1921166 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 "IFT57, Hippi, CHE-13, CG8853, che-13, IFT55, Che-13" IPR019530:Intra-flagellar transport protein 57 CG8853 11-Aug-17 DroID_v2017_08 Drer\ift57 - Cele\che-13 Xtro\ift57 Mmus\Ift57 Hsap\IFT57 FBgn0024861 l(3)96Ba lethal (3) 96Ba http://flybase.org/reports/FBgn0024861 - gene - - - l(3)96Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267009 CR45453 - http://flybase.org/reports/FBgn0267009 non_protein_coding_gene - - - CR45453 - CR45453 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065397 l(2)SH1612 lethal (2) SH1612 http://flybase.org/reports/FBgn0065397 gene - - - "l(2)SH1612, l(2)SH2 1612" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086603 snoRNA:Or-CD2 - http://flybase.org/reports/FBgn0086603 snoRNA_gene - - - "snoRNA:Or-CD2, orphan-CD2, snoRNA:461, Dm-461, snoR461, CR33636, DmOr_cd2 snoRNA, snoRNA:Or-cd2, DmOr_cd2(SnoR461), chr2R:4608869..4608988, Or-CD2" - CR33636 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014313 l(3)ry111 lethal (3) ry111 http://flybase.org/reports/FBgn0014313 - gene - - - l(3)ry111 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051389 CG31389 - http://flybase.org/reports/FBgn0051389 protein_coding_gene - - - CG31389 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,visible,body color defective" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC12860 E -0.078660134 0.317929658 1.667566496 -0.839669311 -0.417453656 0.525698745 FBgn0065389 l(2)SH1631 lethal (2) SH1631 http://flybase.org/reports/FBgn0065389 gene - - - "l(2)SH1631, l(2)SH2 1631" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000193 Bl Bristle http://flybase.org/reports/FBgn0000193 - gene - - - "Sy, Sy[31l], Bl, bl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" "macrochaeta,eye" FBgn0086212 flt-2 - http://flybase.org/reports/FBgn0086212 gene - - - flt-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084023 CG41462 - http://flybase.org/reports/FBgn0084023 protein_coding_gene - - - CG41462 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265902 CR44691 - http://flybase.org/reports/FBgn0265902 non_protein_coding_gene - - - "CR44691, lincRNA.1010" - CR44691 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266061 Su(var)301 - http://flybase.org/reports/FBgn0266061 gene - - - "Su(var)301, 301" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0005270 l(3)SG90 lethal (3) SG90 http://flybase.org/reports/FBgn0005270 - gene - - - "l(3)K60, l(3)SG90" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0004649 yl yolkless http://flybase.org/reports/FBgn0004649 "FBgn0000732, FBgn0004043" protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 vitellogenin receptor activity ; GO:0008196 | inferred from sequence or structural similarity" oogenesis ; GO:0048477 | traceable author statement oogenesis ; GO:0048477 | non-traceable author statement cytoplasmic vesicle ; GO:0031410 | inferred from direct assay coated vesicle ; GO:0030135 | inferred from direct assay "CT3114, DmYPR, LR13, fs(1)L186, fs(1)yolkless, fs(1)M25, fs(1)A148, fs(1)148, fs(1)K184, fs(1)yl, fs(1)M205, fs(1)L211, fs(1)L196, fs(1)L193, fs(1)5, CG1372, yl, Yl, YL" "IPR018097:EGF-like calcium-binding, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR000033:LDLR class B repeat, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR013032:EGF-like, conserved site, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR026823:Complement Clr-like EGF domain" CG1372 11-Aug-17 DroID_v2017_08 "Drer\lrp2a, Drer\lrp5, Drer\lrp1ba, Drer\lrp1bb, Drer\egf, Drer\lrp1ab" "Scer\APM3, Scer\APM2, Scer\APM1" "Cele\lrp-1, Cele\lrp-2" "Xtro\egf, Xtro\lrp2" "Mmus\Lrp6, Mmus\Lrp4, Mmus\Lrp1b, Mmus\C9, Mmus\Lrp2, Mmus\Egf, Mmus\Lrp1, Mmus\Lrp5, Mmus\Gm19410" "Hsap\EGF, Hsap\LRP6, Hsap\LRP1, Hsap\LRP1B, Hsap\LRP2, Hsap\LRP5, Hsap\LRP4" oogenesis stage && adult stage | female ovary

"female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female sterile soma-dependent,viable" "chorion,yolk granule,adult hemolymph,female,egg,maternal effect,stage S10 oocyte,stage S13 oocyte,stage S14 oocyte,coated pit,coated vesicle,stage S10 oocyte & clathrin-coated vesicle" FBgn0004608 fur fused rhabdomeres http://flybase.org/reports/FBgn0004608 - gene - - - fur - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,wild-type" "rhabdomere,optic lobe,retina,lamina,medulla" FBgn0065929 l(2)SH0139 lethal (2) SH0139 http://flybase.org/reports/FBgn0065929 gene - - - "l(2)SH0139, l(2)SH2 0139" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039805 Cpr100A Cuticular protein 100A http://flybase.org/reports/FBgn0039805 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr100A, CG12045, DmelCpr100A" IPR000618:Insect cuticle protein CG12045 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0004913 Gnf1 Germ line transcription factor 1 http://flybase.org/reports/FBgn0004913 "FBgn0010351, FBgn0020380, FBgn0025510" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR012178, InterPro:IPR013725 DNA clamp loader activity ; GO:0003689 | inferred from electronic annotation with InterPro:IPR012178, InterPro:IPR013725 DNA binding ; GO:0003677 | inferred from direct assay DNA binding ; GO:0003677 | non-traceable author statement" "DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR008921, InterPro:IPR012178, InterPro:IPR013725 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR012178 lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA replication ; GO:0006260 | non-traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" "DNA replication factor C complex ; GO:0005663 | inferred from electronic annotation with InterPro:IPR012178, InterPro:IPR013725 microtubule associated complex ; GO:0005875 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay" "dRF-Cp140, RFC, RF-C 140, ONF-CAACAA, GTF-1, gtf1, RfC140, Gtf1, Gnf-1, CG1119, Gnf1, gnf1, RfC, DmRFC1, RFC1, rfc1, dRFC140" "IPR001357:BRCT domain, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR012178:Replication factor C subunit 1, IPR013725:DNA replication factor RFC1, C-terminal, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1119 11-Aug-17 DroID_v2017_08 Drer\rfc1 Scer\RFC1 Cele\rfc-1 Xtro\rfc1 Mmus\Rfc1 Hsap\RFC1 "lethal,recessive,neuroanatomy defective,viable,visible" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell,mesothoracic tergum" DRSC12351 IE -0.717906792 -1.755126068 -1.760259825 -1.436493771 0.746828196 0.275440347 FBgn0085561 CG41229 - http://flybase.org/reports/FBgn0085561 protein_coding_gene - - - CG41229 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003052 pe petit http://flybase.org/reports/FBgn0003052 - gene - - - pe - - 11-Aug-17 DroID_v2017_08 - - - - - - "female fertile,reduced,visible,viable" eye FBgn0262622 CR43146 - http://flybase.org/reports/FBgn0262622 non_protein_coding_gene - - - "CG43146, CR43146, lincRNA.537" - CR43146 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0284084 wg wingless http://flybase.org/reports/FBgn0284084 protein_coding_gene "frizzled-2 binding ; GO:0005110 | inferred from direct assay frizzled-2 binding ; GO:0005110 | inferred from genetic interaction with fz2 morphogen activity ; GO:0016015 | traceable author statement Notch binding ; GO:0005112 | traceable author statement frizzled-2 binding ; GO:0005110 | inferred from physical interaction with fz2 frizzled binding ; GO:0005109 | inferred from physical interaction with fz, fz2, fz3 extracellular matrix binding ; GO:0050840 | inferred from direct assay glycosaminoglycan binding ; GO:0005539 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8N474 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95ST2 heparan sulfate proteoglycan binding ; GO:0043395 | inferred from physical interaction with Cow" "histoblast morphogenesis=0007488 ... positive .. cell proliferation=0008284 ... proboscis=0048728 ... Wnt signaling pathway, calcium modulating pathway=0007223 | inferred from direct assay imaginal disc-derived wing morphogenesis=0007476 ... anterior/posterior axis specification, embryo=0008595 | .. Wnt signaling pathway, calcium modulating pathway=0007223... wing cell fate specification=0035311 ... larval visceral muscle=0007523 ... hindgut morphogenesis=0007442 ... dorsal closure=0007391 ... dorsal closure, elongation of leading edge cells=0007394 ... filopodium assembly=0046847 ... lamellipodium assembly=0030032 ... positive .. compound eye retinal cell programmed cell death=0046672 ... compound eye morphogenesis=0001745 ... labial disc=0035217 ... genital disc primordium=0035225 ... genital disc sexually dimorphic=0035263 ... segment polarity determination=0007367 ... spiracle morphogenesis, open tracheal system=0035277 ... mesoderm morphogenesis=0048332 ... cuticle pattern formation=0035017 ... dorsal/ventral pattern formation, imaginal disc=0007450 | .. leg disc proximal/distal pattern formation=0007479 | .. imaginal disc growth=0007446 | .. imaginal disc pattern formation=0007447 | .. epidermis=0008544 ... leg disc proximal/distal pattern formation=0007479 | .. genital disc=0035215 | .. cell proliferation=0042127 | .. anterior/posterior axis specification, embryo=0008595 | .. ommatidial rotation=0016318 | .. ventral cord=0007419 | .. instar larval=0002168 | .. wing disc dorsal/ventral pattern formation=0048190 | .. mitotic cell cycle=0007346 | .. sensory organ=0007423 | .. anterior head segmentation=0035288 | .. posterior head segmentation=0035289 | .. segment polarity determination=0007367 | .. trunk segmentation=0035290 | .. cardioblast differentiation=0010002 ... lymph gland=0048542 ... imaginal disc=0007444 ... compound eye=0048749 | .. compound eye pigmentation=0048076 ... genital disc anterior/posterior pattern formation=0035224 | inferred from expression pattern ventral midline=0007418 ... negative .. cell fate specification=0009996 ... actin filament bundle assembly=0051017 ... positive .. cell proliferation=0008284 | with Sox15 wing disc=0035220 .. stem cell proliferation=0072091 ... neuroblast=0014019 ... heart=0007507 ... mesoderm=0007498 ... ectoderm=0007398 ... negative .. heart induction by canonical Wnt signaling pathway=0003136 ... heart formation=0060914 ... canonical Wnt signaling pathway=0060070 ... anterior/posterior pattern specification, imaginal disc=0007448 ... dorsal/ventral pattern formation, imaginal disc=0007450 ... ovarian follicle cell=0030707 ... branch fusion, open tracheal system=0035147 ... epithelial cell type specification, open tracheal system=0035153 ... branching morphogenesis of an epithelial tube=0048754 ... canonical Wnt signaling pathway=0060070 | with fz negative .. DNA endoreduplication=0032876 ... negative .. hemocyte differentiation=0045611 ... larval lymph gland hemopoiesis=0035167 ... lymph gland crystal cell differentiation=0035170 ... positive .. crystal cell differentiation=0042691 ... negative .. transcription, DNA-templated=0045892 ... transcription, DNA-templated=0006355 ... pericardial nephrocyte differentiation=0061320 ... posterior Malpighian tubule=0061328 ... Malpighian tubule bud morphogenesis=0061332 ... epithelial cell proliferation involved in Malpighian tubule morphogenesis=0061331 ... Malpighian tubule tip cell differentiation=0061382 ... positive .. stem cell proliferation=2000648 ... negative .. apoptotic process=0043066 | .. long-term memory=0007616 ...imaginal disc-derived wing size=0044719 ... synapse organization=0050808 ... synaptic growth at neuromuscular junction=0051124 ... positive .. cell death=0010942 ..." membrane raft ; GO:0045121 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement extracellular region ; GO:0005576 | traceable author statement early endosome ; GO:0005769 | colocalizes_with inferred from direct assay late endosome ; GO:0005770 | colocalizes_with inferred from direct assay endocytic vesicle ; GO:0030139 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay multivesicular body ; GO:0005771 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | non-traceable author statement "wg, Wg, Wnt, beta-catenin, CG4889, wnt, dWnt, DWnt-1, WNT, DWint-1, Wnt1, Wnt-1, Sp, l(2)02657, Dm-1, I, int-1, l(2)wg, spd, l(2)rO727, fg, Gla, Dint-1, Br, wgl, WG, wnt1, Dm Wg, Wnt/Wg, l(2)SH1281, l(2)SH2 1281, wingless" "IPR018161:Wnt protein, conserved site, IPR005817:Wnt" CG4889 11-Aug-17 DroID_v2017_08 "Drer\wnt10b, Drer\wnt7bb, Drer\wnt5a, Drer\wnt3, Drer\wnt9b, Drer\wnt3a, Drer\wnt2bb, Drer\wnt1, Drer\wnt5b, Drer\wnt11, Drer\wnt6b, Drer\wnt10a, Drer\wnt4a, Drer\wnt7aa, Drer\wnt16, Drer\wnt8b, Drer\wnt8a, Drer\wnt4b, Drer\wnt6a, Drer\LOC568110, Drer\wnt11r, Drer\wnt7ba, Drer\wnt2ba, Drer\wnt2, Drer\wnt9a" - "Cele\cwn-1, Cele\egl-20, Cele\cwn-2, Cele\mom-2" "Xtro\wnt11r, Xtro\wnt9b, Xtro\wnt1, Xtro\wnt4, Xtro\wnt11, Xtro\wnt8b, Xtro\wnt3a, Xtro\wnt16, Xtro\wnt2b, Xtro\wnt7b, Xtro\wnt8a, Xtro\wnt7a, Xtro\wnt7c, Xtro\wnt5b, Xtro\wnt10b, Xtro\wnt9b.2" "Mmus\Wnt9b, Mmus\Wnt4, Mmus\Wnt2, Mmus\Wnt6, Mmus\Wnt9a, Mmus\Wnt3, Mmus\Wnt2b, Mmus\Wnt1, Mmus\Wnt5b, Mmus\Wnt10a, Mmus\Wnt10b, Mmus\Wnt8a, Mmus\Wnt3a, Mmus\Wnt11, Mmus\Wnt5a, Mmus\Wnt7b, Mmus\Wnt7a, Mmus\Wnt16, Mmus\Wnt8b" "Hsap\WNT1, Hsap\WNT4, Hsap\WNT5A, Hsap\WNT5B, Hsap\WNT3A, Hsap\WNT11, Hsap\WNT6, Hsap\WNT16, Hsap\WNT2, Hsap\WNT9A, Hsap\WNT2B, Hsap\WNT8A, Hsap\WNT8B, Hsap\WNT9B, Hsap\WNT3, Hsap\WNT10B, Hsap\WNT7B, Hsap\WNT7A, Hsap\WNT10A" "lethal,recessive" FBgn0050135 CG30135 - http://flybase.org/reports/FBgn0050135 protein_coding_gene - - - CG30135 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259527 B0010 - http://flybase.org/reports/FBgn0259527 gene - - - B0010 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0001932 l(2)25Ee lethal (2) 25Ee http://flybase.org/reports/FBgn0001932 - gene - - - "jf29, l(2)gdh-9, l(2)jf29, l(2)gdh9, l(2)25Ee" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011864 tRNA:Gly-GCC-1-6 transfer RNA:Glycine-GCC 1-6 http://flybase.org/reports/FBgn0011864 "FBgn0003779, FBgn0051982, FBgn0060220" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "BG:DS04641.5, AE002690.trna17-GlyGCC, tRNA:G:GCC:AE002690-e, CR31982, tRNA:gly3:35Bc, tRNA[Gly-GCC], chr2L.trna26-GlyGCC, tRNA-Gly-GCC-1-6, tRNA:Gly-GCC-1-6, tRNA:G3:35Bc, GGC" - CR31982 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036627 Gagr Gag-related http://flybase.org/reports/FBgn0036627 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4680, Gagr, Grp" - CG4680 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023059 l(1)2Ec lethal (1) 2Ec http://flybase.org/reports/FBgn0023059 - gene - - - "D3/36.6, l(1)2Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086884 Wed - http://flybase.org/reports/FBgn0086884 gene - - - Wed - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,male fertile,viable,female,poor,male,visible,dominant" "eye,ommatidium" FBgn0052673 Rab9E Rab at 9E http://flybase.org/reports/FBgn0052673 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 "anon-AE003451.2, Rab9E, CG32673" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG32673 11-Aug-17 DroID_v2017_08 "Drer\rab33a, Drer\rab35b, Drer\rab1aa, Drer\rab35a, Drer\zgc:171927, Drer\rab1bb, Drer\rabl6a, Drer\rab1ab, Drer\si:dkey-16l2.16, Drer\rab19, Drer\rabl6b, Drer\rab1ba, Drer\rsg1, Drer\zgc:101559, Drer\rab43, Drer\rab33ba" "Scer\YPT1, Scer\TEM1" "Cele\rab-28, Cele\rab-35" "Xtro\rab1a, Xtro\rab19, Xtro\rabl6, Xtro\rab33a, Xtro\rab28, Xtro\rab33b" "Mmus\Rab28, Mmus\Rabl6, Mmus\Rab33b, Mmus\Rab19, Mmus\Rab43, Mmus\Rab1b, Mmus\Rab33a, Mmus\Rsg1, Mmus\Rab1a, Mmus\Rab35" "Hsap\RAB43, Hsap\RAB35, Hsap\RAB1B, Hsap\RAB19, Hsap\RSG1, Hsap\RAB28, Hsap\RAB33B, Hsap\RAB33A, Hsap\RABL6, Hsap\RAB1A" FBgn0033724 CG8501 - http://flybase.org/reports/FBgn0033724 protein_coding_gene - - cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN001048184 CG8501 - CG8501 11-Aug-17 DroID_v2017_08 - - Cele\F35C5.11 - - - FBgn0038832 CG15695 - http://flybase.org/reports/FBgn0038832 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG15695, gi7300665, gi21356013" "IPR004245:Protein of unknown function DUF229, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG15695 11-Aug-17 DroID_v2017_08 - - "Cele\Y73F8A.35, Cele\Y38A10A.2, Cele\F10C2.3, Cele\T23E1.1, Cele\T07G12.3, Cele\F07C3.3, Cele\K03A11.4, Cele\Y41E3.1, Cele\F15H10.7, Cele\F32G8.2, Cele\R03G8.1, Cele\M03F8.5, Cele\F32D8.2, Cele\R03G8.3" - - - viable FBgn0062663 EP3186 EP3186 http://flybase.org/reports/FBgn0062663 gene - - - "EP(3)3186, EP3186" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265425 CR44337 - http://flybase.org/reports/FBgn0265425 non_protein_coding_gene - - - CR44337 - CR44337 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036019 Or67b Odorant receptor 67b http://flybase.org/reports/FBgn0036019 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "67b, 67B.2, CG14176, Or67b" "IPR004117:Olfactory receptor, insect" CG14176 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,viable" FBgn0020764 Alas Aminolevulinate synthase http://flybase.org/reports/FBgn0020764 - protein_coding_gene "pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839, InterPro:IPR010961 5-aminolevulinate synthase activity ; GO:0003870 | inferred from sequence or structural similarity with RGD:2084 5-aminolevulinate synthase activity ; GO:0003870 | inferred from sequence or structural similarity with UniProt:P22557 inferred from sequence or structural similarity with UniProtKB:P13196" chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype heme biosynthetic process ; GO:0006783 | inferred from sequence or structural similarity with UniProtKB:P13196 inferred from sequence or structural similarity with UniProtKB:P22557 mitochondrion ; GO:0005739 | inferred from reviewed computational analysis mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProt:P22557 inferred from sequence or structural similarity with UniProtKB:P13196 "Alas, CG3017, alas, ALAS" "IPR004839:Aminotransferase, class I/classII, IPR010961:Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG3017 11-Aug-17 DroID_v2017_08 "Drer\gcat, Drer\alas2, Drer\alas1" Scer\HEM1 Cele\T25B9.1 "Xtro\alas2, Xtro\alas1" "Mmus\Alas1, Mmus\Gcat, Mmus\Alas2" "Hsap\ALAS1, Hsap\ALAS2, Hsap\GCAT" "small body,partially lethal - majority die,some die during pupal stage,lethal" "embryonic/first instar larval cuticle,embryonic/larval tracheal system,procuticle" FBgn0035951 CG5068 - http://flybase.org/reports/FBgn0035951 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from biological aspect of ancestor with PANTHER:PTN000367041 protein methylesterase activity ; GO:0051723 | inferred from biological aspect of ancestor with PANTHER:PTN000367039 protein demethylation ; GO:0006482 | inferred from biological aspect of ancestor with PANTHER:PTN000367039 - CG5068 "IPR000639:Epoxide hydrolase-like, IPR000073:Alpha/beta hydrolase fold-1, IPR016812:Protein phosphatase methylesterase, eukaryotic, IPR029058:Alpha/Beta hydrolase fold" CG5068 11-Aug-17 DroID_v2017_08 Drer\ppme1 Scer\PPE1 Cele\B0464.9 Xtro\ppme1 Mmus\Ppme1 Hsap\PPME1 viable FBgn0014974 l(1)13Fd lethal (1) 13Fd http://flybase.org/reports/FBgn0014974 - gene - - - "IX, l(1)IX, l(1)13Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,lethal,recessive" FBgn0060646 l(3)S083902b lethal (3) S083902b http://flybase.org/reports/FBgn0060646 gene - - - "0839/02, l(3)S083902b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264505 CR43904 - http://flybase.org/reports/FBgn0264505 non_protein_coding_gene - - - CR43904 - CR43904 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033952 Adgf-E Adenosine deaminase-related growth factor E http://flybase.org/reports/FBgn0033952 protein_coding_gene "adenosine deaminase activity ; GO:0004000 | NOT inferred from sequence or structural similarity with Adgf-A, Adgf-D inferred from direct assay growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "adenosine catabolic process ; GO:0006154 | NOT inferred from sequence or structural similarity with Adgf-A, Adgf-D inferred from direct assay cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR006331, InterPro:IPR013659" "ADGF-E, CG10143, adgfe, Adgf-E" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG10143 11-Aug-17 DroID_v2017_08 "Drer\cecr1a, Drer\adal, Drer\ada, Drer\cecr1b" Scer\AAH1 "Cele\C06G3.5, Cele\C44B7.12" "Xtro\ada.2, Xtro\ada, Xtro\adal, Xtro\cecr1" "Mmus\Adal, Mmus\Ada" "Hsap\ADAL, Hsap\ADA, Hsap\CECR1" FBgn0053651 CG33651 - http://flybase.org/reports/FBgn0053651 protein_coding_gene - - - "anon-EST:Liang-1.3, clone 1.3, CG33651" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264296 CG43774 - http://flybase.org/reports/FBgn0264296 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43774, CG10039" - CG43774 11-Aug-17 DroID_v2017_08 - "Scer\APC2, Scer\LTV1" Cele\apc-2 - Mmus\Anapc2 Hsap\ANAPC2 viable FBgn0011904 tRNA:Lys-TTT-2-4 transfer RNA:Lysine-TTT 2-4 http://flybase.org/reports/FBgn0011904 "FBgn0003793, FBgn0011901, FBgn0051486, FBgn0060176" tRNA_gene AAA codon-amino acid adaptor activity ; GO:0033443 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033443 cytosol ; GO:0005829 | inferred by curator from GO:0033443 "CR31486, lys5:84ABa, lys-tRNA-5, Lys-5, AE002699.trna4-LysTTT, tRNA:K5, tRNA:K:TTT:AE002699-a, tRNA:lys5:84AB, BG:DS00276.1, chr3R.trna77-LysTTT, tRNA-Lys-TTT-2-4, tRNA:Lys-TTT-2-4, tRNA:K5:84ABa, AAA" - CR31486 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024911 anon-16Fa anon-16Fa http://flybase.org/reports/FBgn0024911 - gene - - - "F-b, anon-16Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027783 SMC2 Structural maintenance of chromosomes 2 http://flybase.org/reports/FBgn0027783 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR010935 ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with SGD:S000001927 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with HGNC:14011 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with SGD:S000001927 neurogenesis ; GO:0022008 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype condensin complex ; GO:0000796 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay condensin complex ; GO:0000796 | inferred from direct assay condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:14011 condensed chromosome ; GO:0000793 | colocalizes_with inferred from direct assay "DmSMC2, CG10212, SMC2, AAF58197, dSMC2, smc-2, Smc2" "IPR003395:RecF/RecN/SMC, N-terminal, IPR010935:SMCs flexible hinge, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024704:Structural maintenance of chromosomes protein" CG10212 11-Aug-17 DroID_v2017_08 "Drer\smc2, Drer\si:ch211-1o7.3" Scer\SMC2 "Cele\mix-1, Cele\spd-5" Xtro\smc2 Mmus\Smc2 Hsap\SMC2 "viable,fertile,enhancer of variegation,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval brain,mitosis & nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0067336 mir-84 mir-84 http://flybase.org/reports/FBgn0067336 miRNA_gene - - - "miR-84, mir-84" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267795 Frl Formin-like http://flybase.org/reports/FBgn0267795 protein_coding_gene "actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR010472, InterPro:IPR010473 Rho GTPase binding ; GO:0017048 | inferred from electronic annotation with InterPro:IPR010473 actin binding ; GO:0003779 | inferred from sequence or structural similarity" actin cytoskeleton organization ; GO:0030036 | inferred from electronic annotation with InterPro:IPR010473 ommatidial rotation ; GO:0016318 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from genetic interaction with Cdc42 inferred from genetic interaction with DAAM cellular_component ; GO:0005575 | no biological data available "CG32138, Q9VUC6_DROME, Q9VUC5_DROME, CG6807, anon-WO0172774.98, CG13485, CG43986, Frl, frl" "IPR010472:Formin, FH3 domain, IPR014767:Diaphanous autoregulatory (DAD) domain, IPR014768:Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425:Formin, FH2 domain, IPR010473:Formin, GTPase-binding domain, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG32138 11-Aug-17 DroID_v2017_08 "Drer\fmnl2b, Drer\fmnl1b, Drer\fmnl1a, Drer\inf2, Drer\fmnl2a, Drer\daam1b, Drer\fhdc4, Drer\grid2ipb, Drer\fmnl3" "Scer\BNR1, Scer\BNI1" "Cele\frl-1, Cele\exc-6, Cele\fozi-1, Cele\cyk-1, Cele\daam-1" "Xtro\fmnl1, Xtro\inf2, Xtro\fmnl2" "Mmus\Fmnl1, Mmus\Daam1, Mmus\Diaph3, Mmus\Fmnl3, Mmus\Grid2ip, Mmus\Inf2, Mmus\Fmnl2, Mmus\Diaph1, Mmus\Daam2, Mmus\Diaph2" "Hsap\DIAPH2, Hsap\GRID2IP, Hsap\INF2, Hsap\FMNL1, Hsap\DIAPH3, Hsap\FMNL2, Hsap\DIAPH1, Hsap\FMNL3, Hsap\DAAM2, Hsap\DAAM1" FBgn0038436 Gyc89Db Guanylyl cyclase at 89Db http://flybase.org/reports/FBgn0038436 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR011644 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:Q8INF0 guanylate cyclase activity ; GO:0004383 | inferred from direct assay guanylate cyclase activity ; GO:0004383 | contributes_to inferred from direct assay "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 response to reactive oxygen species ; GO:0000302 | inferred from direct assay cGMP biosynthetic process ; GO:0006182 | inferred from direct assay response to hyperoxia ; GO:0055093 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 response to hypoxia ; GO:0001666 | inferred from mutant phenotype" "guanylate cyclase complex, soluble ; GO:0008074 | inferred from direct assay guanylate cyclase complex, soluble ; GO:0008074 | inferred from sequence or structural similarity guanylate cyclase complex, soluble ; GO:0008074 | inferred by curator from GO:0004383 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924" "CG14886, Gyc-89Db, Gyc89Db" "IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR011644:Heme-NO binding, IPR024096:NO signalling/Golgi transport ligand-binding domain, IPR029787:Nucleotide cyclase, IPR011645:Haem NO binding associated" CG14886 11-Aug-17 DroID_v2017_08 "Drer\gucy1b3, Drer\gucy1a2, Drer\gucy1b2, Drer\gucy1a3" - "Cele\gcy-36, Cele\gcy-31, Cele\gcy-34, Cele\gcy-35, Cele\gcy-33, Cele\gcy-37, Cele\gcy-32" "Xtro\gucy1b3, Xtro\gucy1a2" "Mmus\Gucy1a2, Mmus\Gucy1a3, Mmus\Gucy1b2, Mmus\Gucy1b3" "Hsap\GUCY1B3, Hsap\GUCY1A3, Hsap\GUCY1A2" "stress response defective,taste perception defective,viable,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053448 5SrRNA:CR33448 5SrRNA:CR33448 http://flybase.org/reports/FBgn0053448 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33448, 5SrRNA:CR33448" - CR33448 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019849 anon-XV anon-XV http://flybase.org/reports/FBgn0019849 - gene - - - "XV, anon-XV" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262551 Mod(GMroX1)143 - http://flybase.org/reports/FBgn0262551 gene - - - Mod(GMroX1)143 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260658 CG42541 - http://flybase.org/reports/FBgn0260658 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR020849" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 phagocytosis ; GO:0006909 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 "CG42541, CG15240, CG16828, CG16829, BcDNA:RH43809, CG32776" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR020849:Small GTPase superfamily, Ras type, IPR015943:WD40/YVTN repeat-like-containing domain" CG42541 11-Aug-17 DroID_v2017_08 "Drer\hrasb, Drer\rap2ab, Drer\ralaa, Drer\diras1b, Drer\nras, Drer\si:dkeyp-59c12.1, Drer\rhebl1, Drer\rasl11b, Drer\rem1, Drer\rap1aa, Drer\rras2, Drer\ralbb, Drer\diras1a, Drer\si:dkey-27j5.5, Drer\rrad, Drer\zgc:114118, Drer\rergla, Drer\si:ch73-116o1.2, Drer\zgc:152698, Drer\rheb, Drer\zgc:153845, Drer\rasd1, Drer\rem2, Drer\gem, Drer\LOC100332969, Drer\kras, Drer\hrasa, Drer\zgc:110699, Drer\zgc:64022, Drer\rras, Drer\rsg1, Drer\ralab, Drer\rit1, Drer\rap1ab, Drer\rap2b, Drer\ralba, Drer\zgc:171704, Drer\rap2c, Drer\rasl12, Drer\mras, Drer\diras2, Drer\rasl10a, Drer\rerglb, Drer\rasl11a" "Scer\RAS1, Scer\RHB1, Scer\RAS2, Scer\RSR1" Cele\Y52B11A.4 "Xtro\ras-dva, Xtro\ralb, Xtro\rasl10a, Xtro\rap2b, Xtro\rhebl1, Xtro\hras, Xtro\rap1b, Xtro\rala, Xtro\rasl11b, Xtro\diras2, Xtro\nras, Xtro\LOC733456, Xtro\rerg, Xtro\rap2a, Xtro\rasd1, Xtro\gem, Xtro\kras, Xtro\rit1, Xtro\rem1, Xtro\diras3, Xtro\rasd2, Xtro\rheb, Xtro\rem2, Xtro\rergl, Xtro\diras1, Xtro\rap2c, Xtro\rap1a, Xtro\rrad, Xtro\rsg1" "Mmus\Rerg, Mmus\Rasl11a, Mmus\Diras1, Mmus\Kras, Mmus\Gem, Mmus\Gm266, Mmus\Rasl12, Mmus\Rasl11b, Mmus\Rap2b, Mmus\Rasd1, Mmus\Rap2a, Mmus\Nras, Mmus\Rap1a, Mmus\Mras, Mmus\Eras, Mmus\Ralb, Mmus\Rit1, Mmus\Rras2, Mmus\Rsg1, Mmus\Hras, Mmus\Rit2, Mmus\Rem2, Mmus\Rasl10a, Mmus\Rrad, Mmus\Rap2c, Mmus\Rap1b, Mmus\Rergl, Mmus\Rem1, Mmus\Diras2, Mmus\Rasl10b, Mmus\Rheb, Mmus\Rhebl1, Mmus\Rras, Mmus\Rala, Mmus\Rasd2" "Hsap\RHEBL1, Hsap\RIT1, Hsap\RASD1, Hsap\RASL11A, Hsap\NRAS, Hsap\DIRAS2, Hsap\RAP2B, Hsap\RAP2C, Hsap\DIRAS3, Hsap\HRAS, Hsap\ERAS, Hsap\REM1, Hsap\RHEB, Hsap\RERG, Hsap\RRAS, Hsap\GEM, Hsap\RIT2, Hsap\KRAS, Hsap\REM2, Hsap\RAP2A, Hsap\RASL11B, Hsap\RAP1A, Hsap\RASD2, Hsap\RALA, Hsap\RRAS2, Hsap\RALB, Hsap\RASL12, Hsap\RASL10A, Hsap\MRAS, Hsap\RRAD, Hsap\DIRAS1, Hsap\RERGL, Hsap\RASL10B, Hsap\RAP1B, Hsap\RSG1" FBgn0004970 l(1)4Ea lethal (1) 4Ea http://flybase.org/reports/FBgn0004970 - gene - - - l(1)4Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267635 CR45973 - http://flybase.org/reports/FBgn0267635 non_protein_coding_gene - - - CR45973 - CR45973 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010385 Def Defensin http://flybase.org/reports/FBgn0010385 - protein_coding_gene - antibacterial humoral response ; GO:0019731 | inferred from sequence or structural similarity inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | traceable author statement defense response to bacterium ; GO:0042742 | traceable author statement response to bacterium ; GO:0009617 | inferred from expression pattern humoral immune response ; GO:0006959 | inferred from expression pattern defense response to bacterium ; GO:0042742 | non-traceable author statement response to bacterium ; GO:0009617 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "Def, Defensin, 143607_at, CG1385, def, DEF, DIM 26, defensin, Dfn" "IPR001542:Defensin, invertebrate/fungal, IPR003614:Knottin, scorpion toxin-like" CG1385 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage , adult stage " " embryonic/larval fat body

, adult fat body

" viable FBgn0267108 CR45548 - http://flybase.org/reports/FBgn0267108 pseudogene_attribute - - - CR45548 - CR45548 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010118 l(1)16Fe lethal (1) 16Fe http://flybase.org/reports/FBgn0010118 - gene - - - "HL-VI, l(1)16Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive,neurophysiology defective" "wing,leg,adult somatic muscle" FBgn0053556 form3 formin 3 http://flybase.org/reports/FBgn0053556 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR010472 actin binding ; GO:0003779 | inferred from sequence or structural similarity "cellular component organization ; GO:0016043 | inferred from electronic annotation with InterPro:IPR010472 branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype" - "formin/DIA-like, CG18138, CG8633, CG14824, ah1644, CG32384, CG33556, form3, Form3, INF2" "IPR010472:Formin, FH3 domain, IPR014768:Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425:Formin, FH2 domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG33556 11-Aug-17 DroID_v2017_08 "Drer\fmnl2a, Drer\fmn2a, Drer\fhdc3, Drer\fmn2b, Drer\daam1a, Drer\grid2ipb, Drer\inf2, Drer\fhdc4, Drer\grid2ipa, Drer\fmn1, Drer\LOC100148950, Drer\fhdc1, Drer\daam2, Drer\fhdc2, Drer\daam1b" "Scer\BNR1, Scer\BNI1" "Cele\cyk-1, Cele\frl-1, Cele\inft-2, Cele\daam-1, Cele\exc-6" "Xtro\fmn1, Xtro\inf2, Xtro\daam1, Xtro\fhdc1, Xtro\fmnl1, Xtro\grid2ip" "Mmus\Diaph1, Mmus\Fmnl1, Mmus\Diaph2, Mmus\Daam1, Mmus\Daam2, Mmus\Fmnl2, Mmus\Fmnl3, Mmus\Fmn1, Mmus\Diaph3, Mmus\Inf2, Mmus\Fhdc1, Mmus\Grid2ip" "Hsap\FAM47A, Hsap\INF2, Hsap\DAAM2, Hsap\FMNL1, Hsap\DIAPH2, Hsap\FMNL2, Hsap\FMN1, Hsap\DAAM1, Hsap\FMNL3, Hsap\FAM47B, Hsap\DIAPH1, Hsap\GRID2IP, Hsap\FHDC1, Hsap\FAM47C, Hsap\DIAPH3" "lethal,viable,recessive,neuroanatomy defective,oxidative stress response defective,fertile" "presumptive embryonic/larval tracheal system,embryonic/larval dorsal trunk,dorsal trunk primordium,ventral nerve cord commissure,longitudinal connective,ventral nerve cord" FBgn0022315 l(1)D39.5 lethal (1) D39.5 http://flybase.org/reports/FBgn0022315 - gene - - - "D39.5, l(1)D39.5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069138 mcl(3)Z5839 mcl(3)Z5839 http://flybase.org/reports/FBgn0069138 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z5839 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0264741 CG43999 - http://flybase.org/reports/FBgn0264741 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of lipid metabolic process ; GO:0019216 | inferred from biological aspect of ancestor with PANTHER:PTN000281649 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000281649 "CR43999, CG43999, BcDNA:AT03227, CG13602" IPR010754:Optic atrophy 3-like CG43999 11-Aug-17 DroID_v2017_08 Drer\opa3 - Cele\H43I07.1 Xtro\opa3 Mmus\Opa3 Hsap\OPA3 FBgn0036777 CG7341 - http://flybase.org/reports/FBgn0036777 protein_coding_gene - - - CG7341 - CG7341 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003368 sfc stiff chaetae http://flybase.org/reports/FBgn0003368 - gene - - - sfc - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile" macrochaeta FBgn0032452 CG15484 - http://flybase.org/reports/FBgn0032452 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15484 - CG15484 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052203 Spn75F Serpin 75F http://flybase.org/reports/FBgn0052203 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern lateral inhibition ; GO:0046331 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "BG642378(6h1), CG32203, BG642378, Spn75F, 6h1" "IPR000215:Serpin family, IPR023796:Serpin domain" CG32203 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-186e20.7, Drer\serpinf2a, Drer\serpina1, Drer\serpina7, Drer\serpina1l, Drer\zgc:174260, Drer\zgc:174259, Drer\serpine1" - "Cele\srp-7, Cele\srp-2, Cele\srp-1, Cele\srp-6, Cele\srp-3" Xtro\serpinf2 "Mmus\Serpina11, Mmus\Serpina3j, Mmus\Serpina12, Mmus\Serpina1e, Mmus\Serpina16, Mmus\Serpina5, Mmus\Serpina1b, Mmus\Serpina1a, Mmus\Serpina1f, Mmus\Serpina3c, Mmus\Serpina1d, Mmus\Serpina3i, Mmus\Serpinf2, Mmus\Serpina7, Mmus\Serpina3m, Mmus\Serpina6, Mmus\Serpina1c, Mmus\Serpina3k, Mmus\Serpina3a, Mmus\Serpina9, Mmus\Serpina3f, Mmus\Serpina3n, Mmus\Serpina3b, Mmus\Serpina3g" "Hsap\SERPINA5, Hsap\SERPINA3, Hsap\SERPINA4, Hsap\SERPINA6, Hsap\SERPINA1, Hsap\SERPINA9, Hsap\SERPINA2, Hsap\SERPINA12, Hsap\SERPINF2, Hsap\SERPINA11, Hsap\SERPINA7" "viable,fertile,visible" "chaeta,trichogen cell" FBgn0019685 mbr mushroom bodies reduced http://flybase.org/reports/FBgn0019685 - gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mbr - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,male sterile,locomotor behavior defective,female limited" "adult brain,lobula,ellipsoid body,nodulus,calyx of larval mushroom body,calyx of adult mushroom body,lobe system of adult mushroom body" FBgn0002689 mbmC mushroom body miniature C http://flybase.org/reports/FBgn0002689 - gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "opa, mbmC[N28], mbmC" - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,locomotor behavior defective,partially lethal - majority die,female limited" "ellipsoid body,nodulus,antennal lobe,calyx of larval mushroom body,lobe system of adult mushroom body,calyx of adult mushroom body" FBgn0043025 Adgf-A2 Adenosine deaminase-related growth factor A2 http://flybase.org/reports/FBgn0043025 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with protein_id:BAA11812.1 inferred from direct assay growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine deaminase activity ; GO:0004000 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "spermatid development ; GO:0007286 | inferred from expression pattern cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine catabolic process ; GO:0006154 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR006331, InterPro:IPR013659 membrane ; GO:0016020 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model" "ADGF-A2, MSI, BcDNA:AT05468, CG32178, Adgf-A2, Msi" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG32178 11-Aug-17 DroID_v2017_08 "Drer\cecr1b, Drer\ada, Drer\cecr1a, Drer\adal" Scer\AAH1 Cele\C44B7.12 "Xtro\ada, Xtro\cecr1, Xtro\ada.2, Xtro\adal" "Mmus\Ada, Mmus\Adal" "Hsap\ADAL, Hsap\ADA, Hsap\CECR1" " pupal stage , adult stage | male , spermatogenesis && adult stage " " testis

, spermatocyte

" spermatogenesis && adult stage " spermatid

, spermatozoon

, spermatocyte

" viable FBgn0259563 B2016 - http://flybase.org/reports/FBgn0259563 gene - - - B2016 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0029000 ms(3)mntr male sterile minotaurus http://flybase.org/reports/FBgn0029000 gene - - - ms(3)mntr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069167 mcl(3)Z1345 mcl(3)Z1345 http://flybase.org/reports/FBgn0069167 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1345 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0035083 Tina-1 Troponin C-akin-1 http://flybase.org/reports/FBgn0035083 protein_coding_gene structural constituent of muscle ; GO:0008307 | non-traceable author statement heart development ; GO:0007507 | traceable author statement cellular_component ; GO:0005575 | no biological data available "CG2803, BEST:GM14784, Tina-1" "IPR009288:Gamma-glutamylcyclotransferase, AIG2-like, IPR013024:Gamma-glutamyl cyclotransferase-like" CG2803 11-Aug-17 DroID_v2017_08 "Drer\ggact.3, Drer\ggact.1, Drer\ggact.2" - Cele\F42A10.9 Xtro\ggact Mmus\Ggact Hsap\GGACT viable FBgn0013649 ms(2)ry5 ms(2)ry5 http://flybase.org/reports/FBgn0013649 - gene - - - "ms(2)5, ms(2)ry5" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0038601 CG18600 - http://flybase.org/reports/FBgn0038601 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009668 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from electronic annotation with InterPro:IPR009668 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR009668" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR009668 "CG18600, CK01205, BEST:CK01205" "IPR009668:RNA polymerase I associated factor, A49-like" CG18600 11-Aug-17 DroID_v2017_08 Drer\polr1e Scer\RPA49 "Cele\Y45G5AM.7, Cele\rpoa-49" Xtro\polr1e Mmus\Polr1e Hsap\POLR1E viable embryonic/larval hemocyte | third instar larval stage FBgn0001081 fmb fused mushroom bodies http://flybase.org/reports/FBgn0001081 - gene - mushroom body development ; GO:0016319 | inferred from mutant phenotype - "fmb, fum" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mushroom body beta-lobe,mushroom body gamma-lobe,ellipsoid body" FBgn0051338 CR31338 - http://flybase.org/reports/FBgn0051338 non_protein_coding_gene - - - CR31338 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086445 l(2)37Cd lethal (2) 37Cd http://flybase.org/reports/FBgn0086445 protein_coding_gene "RNA polymerase III type 2 promoter sequence-specific DNA binding ; GO:0001003 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000325717 transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting ; GO:0001005 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000325717 RNA polymerase III type 1 promoter sequence-specific DNA binding ; GO:0001002 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000325717" phagocytosis ; GO:0006909 | inferred from mutant phenotype transcription from RNA polymerase III type 2 promoter ; GO:0001009 | inferred from biological aspect of ancestor with PANTHER:PTN000325717 transcription factor TFIIIC complex ; GO:0000127 | inferred from biological aspect of ancestor with PANTHER:PTN000325717 "l(2)37Cd, CG10563, Cd" "IPR019136:Transcription factor IIIC, subunit 5" CG10563 11-Aug-17 DroID_v2017_08 Drer\gtf3c5 Scer\TFC1 Cele\tftc-5 Xtro\gtf3c5 Mmus\Gtf3c5 Hsap\GTF3C5 FBgn0010737 l(3)01107 lethal (3) 01107 http://flybase.org/reports/FBgn0010737 - gene - - - l(3)01107 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015300 Ssl Suppressor of Stellate-like http://flybase.org/reports/FBgn0015300 "FBgn0014036, FBgn0045134" protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity "protein kinase CK2 complex ; GO:0005956 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150" "CK2betates, betaCK2tes, CKIIb1, CG13591, SSL, NEST:bs30a09, Su(Ste)l, Ssl, DmCK2betates, Dm-CK2-beta[Tes]" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG13591 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B "lethal,viable" DRSC04657 K -0.09231576 0.412297162 -1.28937673 -0.339171567 2.5572306 2.199465422 FBgn0067749 l(1)G0206 lethal (1) G0206 http://flybase.org/reports/FBgn0067749 gene - - - l(1)G0206 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085773 CR40766 - http://flybase.org/reports/FBgn0085773 rRNA_gene - - - CR40766 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266942 CR45393 - http://flybase.org/reports/FBgn0266942 non_protein_coding_gene - - - CR45393 - CR45393 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027610 Dic1 Dicarboxylate carrier 1 http://flybase.org/reports/FBgn0027610 - protein_coding_gene inorganic phosphate transmembrane transporter activity ; GO:0005315 | inferred from direct assay oxaloacetate transmembrane transporter activity ; GO:0015131 | inferred from direct assay succinate transmembrane transporter activity ; GO:0015141 | inferred from direct assay malate transmembrane transporter activity ; GO:0015140 | inferred from direct assay sulfate transmembrane transporter activity ; GO:0015116 | inferred from direct assay thiosulfate transmembrane transporter activity ; GO:0015117 | inferred from direct assay antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 succinate transmembrane transport ; GO:0071422 | inferred from direct assay sulfate transport ; GO:0008272 | inferred from direct assay malate transmembrane transport ; GO:0071423 | inferred from direct assay oxaloacetate transport ; GO:0015729 | inferred from direct assay phosphate ion transmembrane transport ; GO:0035435 | inferred from direct assay mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transport ; GO:0015709 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrion ; GO:0005739 | inferred from direct assay "BcDNA:GH02431, CG8790, Dic1, DmDic1p" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG8790 11-Aug-17 DroID_v2017_08 "Drer\slc25a11, Drer\si:ch1073-100f3.2, Drer\slc25a35, Drer\slc25a34, Drer\mrpl12, Drer\slc25a14, Drer\slc25a10, Drer\ucp2" "Scer\DIC1, Scer\OAC1" "Cele\misc-1, Cele\slc-25A10, Cele\mrpl-12, Cele\ucp-4" "Xtro\slc25a27, Xtro\ucp2, Xtro\slc25a10, Xtro\slc25a30, Xtro\rangrf, Xtro\ucp1" "Mmus\Slc25a11, Mmus\Ucp3, Mmus\Slc25a10, Mmus\Slc25a27, Mmus\Mrpl12, Mmus\Slc25a35, Mmus\Slc25a34, Mmus\Ucp1, Mmus\Slc25a14, Mmus\Ucp2, Mmus\Slc25a30" "Hsap\SLC25A34, Hsap\SLC25A30, Hsap\SLC25A35, Hsap\UCP3, Hsap\SLC25A11, Hsap\SLC25A10, Hsap\UCP2, Hsap\UCP1, Hsap\MRPL12, Hsap\SLC25A27, Hsap\SLC25A14" viable FBgn0283499 InR Insulin-like receptor http://flybase.org/reports/FBgn0283499 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002011, InterPro:IPR006211, InterPro:IPR017441 insulin-activated receptor activity ; GO:0005009 | inferred from sequence or structural similarity inferred from direct assay protein tyrosine kinase activity ; GO:0004713 | inferred from mutant phenotype insulin binding ; GO:0043559 | inferred from sequence or structural similarity with UniProtKB:P06213 protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay phosphatidylinositol 3-kinase binding ; GO:0043548 | inferred from sequence or structural similarity with UniProtKB:P06213 insulin-activated receptor activity ; GO:0005009 | inferred from direct assay ATP binding ; GO:0005524 | inferred by curator from GO:0004713 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9XTN2 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement insulin receptor substrate binding ; GO:0043560 | inferred from sequence or structural similarity with UniProtKB:P06213" "regulation of multicellular organism growth=0040014 |...<> negative regulation of autophagy=0010507 |...<> female germ-line stem cell asymmetric division=0048132 |...<> insulin receptor signaling pathway=0008286 |... sequence or structural similarity <> determination of adult lifespan=0008340 | traceable author statement <> positive regulation of multicellular organism growth=0040018 |...<> female mating behavior=0060180 |...<> positive regulation of cell growth=0030307 |...<> regulation of organ growth=0046620 |...<> imaginal disc growth=0007446 |...<> negative regulation of peptide hormone secretion=0090278 |...<> regulation of organ growth=0046620 | <> regulation of reactive oxygen species metabolic process=2000377 |...<> response to cocaine=0042220 |... genetic interaction with EcR <> dorsal closure=0007391 | traceable author statement <> positive regulation of cell size=0045793 | <> germ-band shortening=0007390 | traceable author statement inferred from genetic interaction with peb <> regulation of cell size=0008361 |...<> cholesterol homeostasis=0042632 |...<> growth=0040007 | traceable author statement <> determination of adult lifespan=0008340 |...<> axon guidance=0007411 |...<> nervous system development=0007399 |...<> positive regulation of organ growth=0046622 | traceable author statement <> cell growth=0016049 |...<> insulin receptor signaling pathway=0008286 | <> response to oxidative stress=0006979 |...<> protein autophosphorylation=0046777 |...<> circadian rhythm=0007623 |...<> male germ-line stem cell asymmetric division=0048133 |...<> negative regulation of feeding behavior=2000252 |...<> response to nutrient=0007584 | traceable author statement <> regulation of cell size=0008361 | <> carbohydrate metabolic process=0005975 |...<> insulin receptor signaling pathway=0008286 | traceable author statement <> embryonic development via the syncytial blastoderm=0001700 |... expression pattern <> negative regulation of circadian sleep/wake cycle, sleep=0042321 |...<> primary spermatocyte growth=0007285 |...<> protein phosphorylation=0006468 | <> regulation of cell proliferation=0042127 |...<> somatic muscle development=0007525 |...<> germ-line stem-cell niche homeostasis=0060250 |...<> trachea morphogenesis=0060439 |...<> myoblast fusion=0007520 |...<> insulin receptor signaling pathway=0008286 |... direct assay <> embryonic development via the syncytial blastoderm=0001700 | traceable author statement <> regulation of multicellular organism growth=0040014 | traceable author statement <> ovarian follicle cell development=0030707 |...<> developmental growth=0048589 |...<> embryo development=0009790 |... expression pattern <> positive regulation of multicellular organism growth=0040018 | traceable author statement <> positive regulation of cell growth=0030307 | <> vitellogenesis=0007296 | traceable author statement <> positive regulation of organ growth=0046622 |...<> female gonad development=0008585 |...<> intestinal stem cell homeostasis=0036335 |... genetic interaction with mir-305 <> aging=0007568 |...<> regulation of glucose metabolic process=0010906 |...<> lipid metabolic process=0006629 |...<> multicellular organism growth=0035264 |...<> protein heterotetramerization=0051290 |... sequence or structural similarity with UniProtKB:P06213 <> locomotory behavior=0007626 |...<> cellular response to DNA damage stimulus=0006974 |...<> positive regulation of cell size=0045793 | traceable author statement <> response to anoxia=0034059 |... direct assay <> axon guidance=0007411 | traceable author statement <> positive regulation of cell proliferation=0008284 |...<> positive regulation of organ growth=0046622 | <> neuron remodeling=0016322 |...<> protein phosphorylation=0006468 |...<> protein autophosphorylation=0046777 |... sequence or structural similarity with UniProtKB:P06213" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:5465 inferred from sequence or structural similarity with HGNC:6091 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity insulin receptor complex ; GO:0005899 | inferred from direct assay cell-cell junction ; GO:0005911 | inferred from direct assay "InR, dInR, sprout, CG18402, dinr, InsR, Inr, DInr, dInr, DInR, DIR, insulin/insulin-like growth factor receptor, inr, dIR, INR, l(3)05545, IR, dir, DIRbeta, DIRH, DIHR, dInsR, DILR, dIRH, er10, l(3)er10, l(3)93Dj, Inr-beta, Inr-alpha, Dir-b, Dir-a, dINR, INS, 18402, lnR, inR" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR000494:Receptor L-domain, IPR000719:Protein kinase domain, IPR002011:Tyrosine-protein kinase, receptor class II, conserved site, IPR003961:Fibronectin type III, IPR006211:Furin-like cysteine-rich domain, IPR006212:Furin-like repeat, IPR008266:Tyrosine-protein kinase, active site, IPR009030:Growth factor receptor cysteine-rich domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR013783:Immunoglobulin-like fold" CG18402 11-Aug-17 DroID_v2017_08 "Drer\igf1rb, Drer\igf1ra, Drer\insra, Drer\insrb" - "Cele\T08D2.7, Cele\daf-2" "Xtro\insrr, Xtro\insr, Xtro\igf1r" "Mmus\Insrr, Mmus\Igf1r, Mmus\Insr" "Hsap\INSRR, Hsap\IGF1R, Hsap\INSR" "decreased cell growth,somatic clone" "terminal tracheal cell,eye,somatic clone" FBgn0045469 Gr93c Gustatory receptor 93c http://flybase.org/reports/FBgn0045469 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr93c, Gr93F3, CG13411, 93F.3, GR93F.3, CG31173, GR93c" IPR013604:7TM chemoreceptor CG31173 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0260122 2L0445 - http://flybase.org/reports/FBgn0260122 gene - - - 2L0445 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "embryonic/larval dorsal trunk,somatic clone,embryonic/larval transverse connective,embryonic/larval tracheal system" FBgn0029837 Tsp5D Tetraspanin 5D http://flybase.org/reports/FBgn0029837 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model "CG4690, Dm.Tsp5D, Tsp5D, tsp5D" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG4690 11-Aug-17 DroID_v2017_08 "Drer\cd63, Drer\tspan18b, Drer\tspan4b, Drer\tspan35, Drer\tspan9a, Drer\tspan18a, Drer\tspan34, Drer\zgc:64051, Drer\tspan4a, Drer\tspan12, Drer\tspan37, Drer\tspan9b" - "Cele\tsp-14, Cele\tsp-21, Cele\tsp-2, Cele\tsp-7, Cele\tsp-1, Cele\tsp-3" "Xtro\tspan9, Xtro\tspan1, Xtro\tspan16, Xtro\LOC100145428, Xtro\tspan18, Xtro\tspan4, Xtro\cd53" "Mmus\Cd63, Mmus\Cd53, Mmus\Tspan4, Mmus\Tspan12, Mmus\Tspan9, Mmus\Tspan1, Mmus\Tspan18" "Hsap\TSPAN4, Hsap\CD53, Hsap\CD63, Hsap\TSPAN12, Hsap\TSPAN16, Hsap\TSPAN1, Hsap\TSPAN18, Hsap\TSPAN9" viable FBgn0264511 CR43910 - http://flybase.org/reports/FBgn0264511 non_protein_coding_gene - - - CR43910 - CR43910 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030906 CG15063 - http://flybase.org/reports/FBgn0030906 protein_coding_gene - - - CG15063 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266995 CR45446 - http://flybase.org/reports/FBgn0266995 non_protein_coding_gene - - - CR45446 - CR45446 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037962 CG6971 - http://flybase.org/reports/FBgn0037962 protein_coding_gene dynein heavy chain binding ; GO:0045504 | inferred from sequence or structural similarity with MGI:MGI:1922813 inner dynein arm assembly ; GO:0036159 | inferred from sequence or structural similarity with UniProtKB:Q39604 cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:Q39604 inner dynein arm ; GO:0036156 | inferred from sequence or structural similarity with UniProtKB:Q39604 "anon-WO0140519.67, CG6971, DNALI1" IPR019347:Axonemal dynein light chain CG6971 11-Aug-17 DroID_v2017_08 Drer\dnali1 - Cele\dyla-1 Xtro\dnali1 Mmus\Dnali1 Hsap\DNALI1 viable FBgn0005186 l(2)S32 lethal of Seto 32 http://flybase.org/reports/FBgn0005186 - gene - - - l(2)S32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "wing,leg,pupa" FBgn0039356 CG5039 - http://flybase.org/reports/FBgn0039356 protein_coding_gene - - - "BcDNA:LD35121, CG5039" - CG5039 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0052382 sphinx2 sphinx2 http://flybase.org/reports/FBgn0052382 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred by curator from GO:0050832 "sphinx2, CG32382, SPH194, CG8555, Sphinx2" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG32382 11-Aug-17 DroID_v2017_08 "Drer\ela3l, Drer\ctrb1, Drer\masp2, Drer\LOC562139" - - Xtro\prtn3 "Mmus\Klk1b3, Mmus\Klk14, Mmus\C1s2, Mmus\C1s1, Mmus\Hgf" "Hsap\C1S, Hsap\KLK4" "immune response defective,viable" FBgn0065848 l(2)SH0310 lethal (2) SH0310 http://flybase.org/reports/FBgn0065848 gene - - - "l(2)SH0310, l(2)SH2 0310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031979 CCDC53 Coiled-coil domain containing 53 http://flybase.org/reports/FBgn0031979 protein_coding_gene - - WASH complex ; GO:0071203 | inferred from direct assay WASH complex ; GO:0071203 | inferred from sequence or structural similarity with UniProtKB:Q9Y3C0 "CG7429, CCDC53, Ccdc53, ccdc53" IPR019309:WASH complex subunit 3 CG7429 11-Aug-17 DroID_v2017_08 Drer\ccdc53 - Cele\ddl-1 Xtro\ccdc53 Mmus\Ccdc53 Hsap\WASHC3 "female fertile,viable" FBgn0015382 dust double stalk http://flybase.org/reports/FBgn0015382 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available dust - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267109 CR45549 - http://flybase.org/reports/FBgn0267109 non_protein_coding_gene - - - CR45549 - CR45549 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266927 CR45378 - http://flybase.org/reports/FBgn0266927 non_protein_coding_gene - - - CR45378 - CR45378 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053353 5SrRNA:CR33353 5SrRNA:CR33353 http://flybase.org/reports/FBgn0053353 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33353, 5SrRNA:CR33353" - CR33353 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264886 CR44077 - http://flybase.org/reports/FBgn0264886 non_protein_coding_gene - - - CR44077 - CR44077 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260333 GSd423 - http://flybase.org/reports/FBgn0260333 gene - - - GSd423 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013511 l(1)14Ah lethal (1) 14Ah http://flybase.org/reports/FBgn0013511 - gene - - - "X, l(1)X, l(1)13Fk, l(1)14Ah" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031256 shv shriveled http://flybase.org/reports/FBgn0031256 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR008971 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971 positive regulation of integrin-mediated signaling pathway ; GO:2001046 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "CG4164, shv" "IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site" CG4164 11-Aug-17 DroID_v2017_08 "Drer\zgc:152986, Drer\dnajb11" "Scer\JJJ2, Scer\HLJ1, Scer\YDJ1, Scer\SCJ1, Scer\XDJ1" "Cele\dnj-26, Cele\dnj-20" Xtro\dnajb11 Mmus\Dnajb11 Hsap\DNAJB11 "viable,partially lethal - majority die,recessive" FBgn0029800 lin-52 lin-52 http://flybase.org/reports/FBgn0029800 protein_coding_gene - cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR018737 negative regulation of execution phase of apoptosis ; GO:1900118 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype DRM complex ; GO:0070176 | inferred from electronic annotation with InterPro:IPR018737 nucleus ; GO:0005634 | inferred from direct assay Myb complex ; GO:0031523 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay euchromatin ; GO:0000791 | inferred from direct assay "dLin52, dLIN-52, dLin-52, CG15929, lin-52, dlin-52, dlin52, Lin52, Lin-52" IPR018737:Protein LIN52 CG15929 11-Aug-17 DroID_v2017_08 Drer\lin52 - Cele\lin-52 Xtro\lin52 "Mmus\Lin52, Mmus\Gm7020" Hsap\LIN52 "lethal,visible,somatic clone,germline clone,maternal effect,mitotic cell cycle defective,viable" "eye,somatic clone,rhabdomere | adult stage | somatic clone,ommatidium,embryo,germline clone,maternal effect,mitotic spindle | germline clone | maternal effect,metaphase plate | germline clone | maternal effect" DRSC18106 IE 1.579871404 0.184454313 3.440157772 -0.5260314 -0.496899688 -0.965500096 FBgn0043454 EP639 BEST:SD02913 http://flybase.org/reports/FBgn0043454 gene - - - "SD02913, EP639, BEST:SD02913" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "trichogen cell,ectopic,tormogen cell,macrochaeta,adult thorax,chaeta,wing,germline cell,male,eye,scutellar bristle" FBgn0033297 Mal-A8 Maltase A8 http://flybase.org/reports/FBgn0033297 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "CT6532, Mal-A8, mal_A8, CG8690, Drome_A8" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily, IPR022567:Glycosyl hydrolase, C-terminal (DUF3459)" CG8690 11-Aug-17 DroID_v2017_08 "Drer\slc3a2a, Drer\zgc:158423, Drer\si:dkey-202g17.3, Drer\slc3a1, Drer\slc3a2b" "Scer\IMA2, Scer\IMA5, Scer\IMA3, Scer\MAL12, Scer\MAL32, Scer\IMA1, Scer\IMA4" "Cele\atgp-2, Cele\atgp-1" "Xtro\slc3a2, Xtro\slc3a1" "Mmus\Slc3a2, Mmus\Slc3a1" "Hsap\SLC3A1, Hsap\GBE1, Hsap\SLC3A2" viable FBgn0034476 Toll-7 Toll-7 http://flybase.org/reports/FBgn0034476 protein_coding_gene "signaling pattern recognition receptor activity ; GO:0008329 | inferred by curator from GO:0009897,GO:0010508,GO:0046790 virion binding ; GO:0046790 | inferred from direct assay neurotrophin receptor activity ; GO:0005030 | inferred from mutant phenotype" "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000157 cell surface pattern recognition receptor signaling pathway ; GO:0002752 | inferred by curator from GO:0009897,GO:0010508,GO:0046790 positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype" external side of plasma membrane ; GO:0009897 | inferred from direct assay "Toll-7, dToll7, toll, dTLR7, Tl-7, CT24947, CG8595, TOLL 7, toll-7" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG8595 11-Aug-17 DroID_v2017_08 "Drer\zgc:101569, Drer\tlr4bb, Drer\chadla, Drer\LOC100332783, Drer\tlr3, Drer\tlr8b, Drer\tlr2, Drer\tlr18, Drer\tlr4ba, Drer\lgi1b, Drer\nrros, Drer\lgi1a, Drer\si:dkey-182i3.11, Drer\tlr9, Drer\lgi3, Drer\LOC100332583, Drer\tlr20.2, Drer\tlr5a, Drer\chad, Drer\tlr21, Drer\tlr7, Drer\lgi2a, Drer\cd180, Drer\tlr1, Drer\LOC572462, Drer\LOC100005571, Drer\tlr5b, Drer\chadlb" Scer\CYR1 "Cele\lron-1, Cele\lron-9, Cele\pan-1, Cele\lron-2, Cele\tol-1" "Xtro\LOC100488097, Xtro\LOC100485512, Xtro\LOC100495326, Xtro\LOC100485201, Xtro\tlr5, Xtro\LOC100485706, Xtro\tlr7, Xtro\tlr3, Xtro\LOC100485164, Xtro\chadl, Xtro\tlr9, Xtro\tlr6, Xtro\tlr2" "Mmus\Tlr2, Mmus\Tlr8, Mmus\Slit1, Mmus\Cd180, Mmus\Tlr5, Mmus\Lgi1, Mmus\Tlr3, Mmus\Chad, Mmus\Lgi3, Mmus\Lgi4, Mmus\Tlr13, Mmus\Chadl, Mmus\Tlr9, Mmus\Lgi2, Mmus\Tlr4, Mmus\Tlr7, Mmus\Tlr1, Mmus\Tlr6, Mmus\Tlr12" "Hsap\CD180, Hsap\TLR7, Hsap\CHAD, Hsap\TLR10, Hsap\LGI3, Hsap\LGI1, Hsap\TLR5, Hsap\TLR1, Hsap\TLR4, Hsap\TLR6, Hsap\CHADL, Hsap\LGI2, Hsap\TLR8, Hsap\LGI4, Hsap\TLR2, Hsap\TLR9, Hsap\TLR3" " embryonic stage -- adult stage , adult stage | male " "immune response defective,lethal,partially lethal - majority die,viable,neuroanatomy defective,decreased cell death" "adult abdomen,macrochaeta,ectopic,eye,wing vein,wing,leg,ventral thoracic disc,wing disc,embryonic/larval central nervous system" FBgn0021804 l(2)k16805 lethal (2) k16805 http://flybase.org/reports/FBgn0021804 - gene - - - l(2)k16805 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030676 CG12379 - http://flybase.org/reports/FBgn0030676 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007853 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein stabilization ; GO:0050821 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 CG12379 "IPR024158:Mitochondrial import protein TIM15, IPR007853:Zinc finger, DNL-type" CG12379 11-Aug-17 DroID_v2017_08 "Drer\card11, Drer\card14, Drer\dnlz, Drer\card9" Scer\ZIM17 Cele\F53A3.7 "Xtro\dnlz, Xtro\card9, Xtro\card14" "Mmus\Card9, Mmus\Dnlz, Mmus\Card14, Mmus\Card11, Mmus\Card10" "Hsap\CARD14, Hsap\DNLZ, Hsap\CARD9, Hsap\CARD10" FBgn0026169 snoRNA:Psi18S-1820 - http://flybase.org/reports/FBgn0026169 - snoRNA_gene - - - "Dm-639, snoR639, H1, snoH1, CR32884, psi18s-1820 snoRNA, snoRNA H1, snoRNA:Psi18S-1820, Psi 18S-1820(SnoR639), snoRNA:H1, Sno H1, chr2R:19683803..19683909" - CR32884 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0000854 fs(1)M46 female sterile (1) M46 http://flybase.org/reports/FBgn0000854 - gene - - - fs(1)M46 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0259991 CG42488 - http://flybase.org/reports/FBgn0259991 protein_coding_gene - outer dynein arm assembly ; GO:0036158 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 cilium movement ; GO:0003341 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 "CG42488, Dromel_CG5116_FBtr0084877_uORF" IPR026788:Transmembrane protein 141 CG42488 11-Aug-17 DroID_v2017_08 Drer\tmem141 - - Xtro\tmem141 Mmus\Tmem141 Hsap\TMEM141 FBgn0052379 CG32379 - http://flybase.org/reports/FBgn0052379 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "CG18415, CG32379" "IPR000834:Peptidase M14, carboxypeptidase A, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain" CG32379 11-Aug-17 DroID_v2017_08 "Drer\cpa4, Drer\cpa6, Drer\cpb2, Drer\cpb1, Drer\cpa1, Drer\cpa5, Drer\cpo, Drer\cpa2" Scer\ECM14 "Cele\cpd-2, Cele\Y59C2A.1, Cele\F02D8.4, Cele\ZC434.9, Cele\T06A4.1, Cele\Y47G6A.19, Cele\Y18H1A.9, Cele\W01A8.6, Cele\suro-1, Cele\T06A4.3" "Xtro\cpa3, Xtro\cpa1, Xtro\cpb1, Xtro\cpo, Xtro\cpb2" "Mmus\Cpa5, Mmus\Cpa3, Mmus\Cpb2, Mmus\Cpd, Mmus\Cpa6, Mmus\Cpb1, Mmus\Cpa4, Mmus\Cpa2, Mmus\Cpa1" "Hsap\CPA6, Hsap\CPA2, Hsap\CPA4, Hsap\CPA3, Hsap\CPB1, Hsap\CPB2, Hsap\CPD, Hsap\CPA5, Hsap\CPA1, Hsap\CPO" FBgn0016939 smiUNK smell impaired unknown http://flybase.org/reports/FBgn0016939 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smiUNK - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive" FBgn0002871 mu1 mutator 1 http://flybase.org/reports/FBgn0002871 - gene - - - "mu, mt, mu1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031981 CG7466 - http://flybase.org/reports/FBgn0031981 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002165 CG7466 "IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR000859:CUB domain, IPR001881:EGF-like calcium-binding domain, IPR002049:Laminin EGF domain, IPR002165:Plexin repeat, IPR013032:EGF-like, conserved site, IPR018097:EGF-like calcium-binding, conserved site, IPR016201:PSI domain, IPR015915:Kelch-type beta propeller, IPR015916:Galactose oxidase, beta-propeller" CG7466 11-Aug-17 DroID_v2017_08 "Drer\tmeff1a, Drer\atrnl1b, Drer\atrnl1a, Drer\megf8, Drer\tmeff2a, Drer\atrn, Drer\tmeff1b, Drer\tmem145, Drer\tmeff2b" - "Cele\unc-52, Cele\tag-53" "Xtro\megf8, Xtro\atrnl1, Xtro\atrn" "Mmus\Tmeff2, Mmus\Atrn, Mmus\Atrnl1, Mmus\Tmeff1, Mmus\Megf8, Mmus\Pafah1b3" "Hsap\ATRN, Hsap\MSANTD3-TMEFF1, Hsap\MEGF8, Hsap\TMEFF2, Hsap\ATRNL1, Hsap\TMEFF1" viable FBgn0283728 CG31600 - http://flybase.org/reports/FBgn0283728 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008952 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG31600, Dm.Tsp40A, Tsp40A" "IPR018499:Tetraspanin/Peripherin, IPR008952:Tetraspanin, EC2 domain" CG31600 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034689 CG2921 - http://flybase.org/reports/FBgn0034689 protein_coding_gene enzyme binding ; GO:0019899 | inferred from sequence or structural similarity with HGNC:17872 protein methylation ; GO:0006479 | inferred from sequence or structural similarity with HGNC:17872 regulation of response to DNA damage stimulus ; GO:2001020 | inferred from sequence or structural similarity with HGNC:17872 cellular_component ; GO:0005575 | no biological data available CG2921 IPR002791:Domain of unknown function DUF89 CG2921 11-Aug-17 DroID_v2017_08 Drer\armt1 Scer\YMR027W Cele\F31D4.2 Xtro\armt1 Mmus\Armt1 Hsap\ARMT1 "viable,fertile" FBgn0263853 GS9605 - http://flybase.org/reports/FBgn0263853 gene - - - GS9605 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060475 l(3)S111703 lethal (3) S111703 http://flybase.org/reports/FBgn0060475 gene - - - "1117/03, l(3)S111703" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0052060 CG32060 - http://flybase.org/reports/FBgn0052060 protein_coding_gene - - - CG32060 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0000851 fs(1)M40 female sterile (1) M40 http://flybase.org/reports/FBgn0000851 - gene - - - fs(1)M40 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0259756 ms(2)Fra-1 - http://flybase.org/reports/FBgn0259756 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - ms(2)Fra-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "Y chromosome loop,spermatozoon" FBgn0027094 AlaRS Alanyl-tRNA synthetase http://flybase.org/reports/FBgn0027094 - protein_coding_gene "alanine-tRNA ligase activity ; GO:0004813 | inferred from electronic annotation with InterPro:IPR018162, InterPro:IPR018164, InterPro:IPR018165, InterPro:IPR023033 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012947, InterPro:IPR018162, InterPro:IPR018164, InterPro:IPR018165 amino acid binding ; GO:0016597 | inferred from biological aspect of ancestor with PANTHER:PTN000206950 alanine-tRNA ligase activity ; GO:0004813 | traceable author statement tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000206904" "alanyl-tRNA aminoacylation ; GO:0006419 | inferred from electronic annotation with InterPro:IPR018162, InterPro:IPR018164, InterPro:IPR018165 tRNA modification ; GO:0006400 | inferred from biological aspect of ancestor with PANTHER:PTN000206950 alanyl-tRNA aminoacylation ; GO:0006419 | traceable author statement" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002318, InterPro:IPR018162 cytoplasm ; GO:0005737 | traceable author statement" "Aats-ala, AlaRS, alaS, ARS, CG13391" "IPR002318:Alanine-tRNA ligase, class IIc, IPR003156:DHHA1 domain, IPR012947:Threonyl/alanyl tRNA synthetase, SAD, IPR009000:Translation protein, beta-barrel domain, IPR018163:Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR018164:Alanyl-tRNA synthetase, class IIc, N-terminal, IPR018165:Alanyl-tRNA synthetase, class IIc, core domain, IPR018162:Alanine-tRNA ligase, class IIc, anti-codon-binding domain, IPR023033:Alanine-tRNA ligase, eukaryota/bacteria" CG13391 11-Aug-17 DroID_v2017_08 "Drer\aars2, Drer\aars" Scer\ALA1 "Cele\aars-1, Cele\aars-2" Xtro\aars "Mmus\Aars2, Mmus\Aars" "Hsap\AARS, Hsap\AARS2" embryonic stage embryonic/larval salivary gland

lethal FBgn0002467 l(3)SG22 lethal (3) SG22 http://flybase.org/reports/FBgn0002467 - gene - - - "l(3)15m-15, l(3)SG22" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0035328 yellow-g2 yellow-g2 http://flybase.org/reports/FBgn0035328 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG13804, yellow-g2, yel-g2, yg2, g2" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG13804 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\F49E11.8, Cele\fbxa-76, Cele\C24H12.1, Cele\T27A1.3" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 viable FBgn0032029 CG17292 - http://flybase.org/reports/FBgn0032029 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR033906 cytosol ; GO:0005829 | inferred from direct assay CG17292 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG17292 11-Aug-17 DroID_v2017_08 "Drer\lipca, Drer\LOC101884800, Drer\LOC100331214, Drer\lipib, Drer\lipia, Drer\lipg, Drer\lpl, Drer\pla1a" - "Cele\clec-97, Cele\clec-110, Cele\clec-203, Cele\clec-103, Cele\clec-106, Cele\clec-245, Cele\ZK39.9, Cele\clec-246, Cele\clec-99, Cele\clec-95, Cele\clec-128, Cele\clec-144, Cele\clec-127, Cele\clec-118, Cele\F17B5.10, Cele\clec-241, Cele\clec-234, Cele\clec-208, Cele\clec-259, Cele\clec-122, Cele\clec-213, Cele\clec-243, Cele\clec-244, Cele\clec-132, Cele\clec-96, Cele\clec-109, Cele\clec-121, Cele\clec-261, Cele\clec-94, Cele\clec-242" "Xtro\lipg, Xtro\lpl" "Mmus\Liph, Mmus\Pla1a, Mmus\Lpl, Mmus\Pnlip, Mmus\Pnliprp2, Mmus\Pnliprp1, Mmus\Lipi, Mmus\Lipc, Mmus\Lipg" "Hsap\LIPH, Hsap\PLA1A, Hsap\PNLIP, Hsap\LIPG, Hsap\PNLIPRP2, Hsap\LPL, Hsap\LIPC, Hsap\PNLIPRP3, Hsap\PNLIPRP1, Hsap\LIPI" viable FBgn0033756 CG17760 - http://flybase.org/reports/FBgn0033756 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000654 G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 phospholipase C-activating dopamine receptor signaling pathway ; GO:0060158 | inferred from biological aspect of ancestor with PANTHER:PTN000026396 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with RGDID:619749 heterotrimeric G-protein complex ; GO:0005834 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with RGDID:619749 "BcDNA:SD21019, CG17760, GNAQ/11/14" "IPR000654:G-protein alpha subunit, group Q, IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17760 11-Aug-17 DroID_v2017_08 "Drer\gnaq, Drer\gna15.2, Drer\gnai2b, Drer\gnat2, Drer\gna11b, Drer\gna15.1, Drer\gnai1, Drer\gna14, Drer\gnai3, Drer\gnao1b, Drer\gna15.4, Drer\gnaz, Drer\gnao1a, Drer\gnav1, Drer\gna14a, Drer\si:ch211-207c7.2, Drer\gna11a, Drer\gnaia, Drer\gnat1" "Scer\GPA1, Scer\GPA2" "Cele\egl-30, Cele\gpa-3, Cele\gpa-7, Cele\odr-3, Cele\gpa-2, Cele\gpa-16, Cele\gpa-1, Cele\gpa-4, Cele\goa-1" "Xtro\gnao1, Xtro\gnai3, Xtro\gna11, Xtro\gnai1, Xtro\gnaq, Xtro\gna14, Xtro\gna15, Xtro\gnat1, Xtro\gnat2, Xtro\gnai2" "Mmus\Gnai3, Mmus\Gnaq, Mmus\Gnaz, Mmus\Gnat2, Mmus\Gnat3, Mmus\Gnao1, Mmus\Gnai1, Mmus\Gna11, Mmus\Gnat1, Mmus\Gna14, Mmus\Gna15, Mmus\Gnai2" "Hsap\GNAT1, Hsap\GNAT2, Hsap\GNAI2, Hsap\GNA15, Hsap\GNAQ, Hsap\GNAI1, Hsap\GNAT3, Hsap\GNAZ, Hsap\GNA11, Hsap\GNA14, Hsap\GNAI3, Hsap\GNAO1" viable DRSC06694 E -0.065895759 0.423783124 1.563835556 0.936346256 -0.037558357 0.284170681 FBgn0266470 pinenut - http://flybase.org/reports/FBgn0266470 gene - - - "pinenut, pine nut" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "egg chamber,somatic clone,oocyte associated follicular epithelium,follicle cell" FBgn0000146 aub aubergine http://flybase.org/reports/FBgn0000146 "FBgn0010310, FBgn0024835" protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay piRNA binding ; GO:0034584 | inferred from direct assay "karyosome formation ; GO:0030717 | traceable author statement positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype RNA interference ; GO:0016246 | traceable author statement RNA interference ; GO:0016246 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from genetic interaction with tud inferred from genetic interaction with vas regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 oogenesis ; GO:0048477 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from genetic interaction with osk regulation of oskar mRNA translation ; GO:0046011 | traceable author statement oocyte maturation ; GO:0001556 | inferred from mutant phenotype targeting of mRNA for destruction involved in RNA interference ; GO:0030423 | inferred from mutant phenotype negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype positive regulation of oskar mRNA translation ; GO:0046012 | traceable author statement maintenance of pole plasm mRNA location ; GO:0046594 | traceable author statement pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype regulation of translational initiation ; GO:0006446 | inferred from sequence or structural similarity with protein_id:AAC24323.1 positive regulation of oskar mRNA translation ; GO:0046012 | non-traceable author statement dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from genetic interaction with nos" P granule ; GO:0043186 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "aub, sting, sti, ms(2)32D, CG6137, AUB, Aub, aubergine" "IPR012337:Ribonuclease H-like domain, IPR003100:PAZ domain, IPR003165:Piwi domain" CG6137 11-Aug-17 DroID_v2017_08 "Drer\ago3b, Drer\piwil2, Drer\ago1, Drer\LOC567622, Drer\ago2, Drer\piwil1" - "Cele\hpo-24, Cele\alg-3, Cele\alg-1, Cele\prg-2, Cele\prg-1, Cele\rde-1" "Xtro\piwil1, Xtro\ago2, Xtro\piwil3, Xtro\ago4, Xtro\piwil2, Xtro\piwil4, Xtro\ago3" "Mmus\Ago3, Mmus\Piwil4, Mmus\Ago2, Mmus\Piwil2, Mmus\Ago1, Mmus\Piwil1, Mmus\Ago4" "Hsap\AGO2, Hsap\PIWIL4, Hsap\AGO1, Hsap\AGO3, Hsap\AGO4, Hsap\PIWIL3, Hsap\PIWIL1, Hsap\PIWIL2" " adult stage | female , adult stage | male " " ovary

, testis

" "lethal,maternal effect,recessive,female sterile,mitotic cell cycle defective,female,lethal - all die before end of embryonic stage,male sterile,wild-type,non-rescuable maternal effect,some die during embryonic stage,suppressor of variegation,non-suppressor of variegation,dominant,viable" "embryo,maternal effect,posterior,dorsal appendage,chorion,female germline stem cell,cystoblast,embryonic/larval cuticle,spermatocyte,spermatid,karyosome" FBgn0262213 mir-2495 mir-2495 stem loop http://flybase.org/reports/FBgn0262213 miRNA_gene - - - "mir-2495, CR42920, dme-mir-2495, miR-2495" - CR42920 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032597 CG17904 - http://flybase.org/reports/FBgn0032597 protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR028601 iron-sulfur cluster binding ; GO:0051536 | inferred from sequence or structural similarity with UniProtKB:P53384" iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with UniProtKB:P53384 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P53384 "CG17904, Nubp1" "IPR019591:Mrp/NBP35 ATP-binding protein, IPR033756:Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35, IPR028601:Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17904 11-Aug-17 DroID_v2017_08 "Drer\nubp2, Drer\nubpl, Drer\nubp1" "Scer\CFD1, Scer\NBP35" Cele\nubp-1 "Xtro\nubp1, Xtro\nubp2, Xtro\nubpl" "Mmus\Nubpl, Mmus\Nubp2, Mmus\Nubp1" "Hsap\NUBP1, Hsap\NUBPL, Hsap\NUBP2" viable FBgn0044824 R1A1-element\ORF2 R1A1-element ORF2 http://flybase.org/reports/FBgn0044824 transposable_element_gene - - - "R1, R1A1-element\ORF2, R1-element\ORF2" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012038 Antp::Scr Antp::Scr http://flybase.org/reports/FBgn0012038 - engineered_fusion_gene - - - Antp::Scr - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" "head,T1 beard,ectopic,mesothoracic segment,metathoracic segment,arista,tarsal segment,eye,occiput,prothoracic segment,metatarsus,third segment of antenna,heat sensitive,femur,embryonic head,adult head,antenna,embryonic/larval salivary gland,thoracic segment,denticle,mesothoracic leg" FBgn0031972 Wwox WW domain containing oxidoreductase http://flybase.org/reports/FBgn0031972 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype regulation of reactive oxygen species metabolic process ; GO:2000377 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG7221, DmWWOX, anon-EST:Posey177, Wwox, WWOX" "IPR001202:WW domain, IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG7221 11-Aug-17 DroID_v2017_08 "Drer\flj13639, Drer\rdh14a, Drer\si:dkey-94e7.2, Drer\si:dkey-174n20.1, Drer\si:dkey-23o4.6, Drer\cbr1, Drer\zgc:153441, Drer\cbr1l, Drer\si:ch211-165b10.3, Drer\zgc:64106, Drer\dhrs12, Drer\si:dkey-73n8.3, Drer\dhrs13a.1, Drer\dhrsx, Drer\hsd17b7, Drer\si:ch211-107o10.3, Drer\dhrs13l1, Drer\rdh14b, Drer\rdh12l, Drer\rdh12, Drer\zgc:112332, Drer\wwox, Drer\dhrs13a.3, Drer\dhrs13a.2" "Scer\ENV9, Scer\YNL181W, Scer\ERG27, Scer\YKL107W" "Cele\K10H10.6, Cele\dhs-8, Cele\DC2.5, Cele\sav-1, Cele\F32A5.8, Cele\E04F6.15, Cele\dhs-17, Cele\dhs-7" "Xtro\rdh14, Xtro\dhrs12, Xtro\rdh13, Xtro\rdh11, Xtro\dhrs13, Xtro\dhrsx" "Mmus\Hsd17b7, Mmus\Cbr3, Mmus\Cbr1, Mmus\Dhrsx, Mmus\Rdh11, Mmus\Rdh12, Mmus\Dhrs13, Mmus\Wwox, Mmus\Rdh13, Mmus\Rdh14, Mmus\1700003E16Rik" "Hsap\WWOX, Hsap\CBR3, Hsap\CBR1, Hsap\DHRS13, Hsap\DHRSX, Hsap\RDH13, Hsap\RDH11, Hsap\RDH14, Hsap\OSTC, Hsap\DHRS12, Hsap\HSD17B7, Hsap\RDH12, Hsap\C2orf81" "viable,fertile" DRSC22872 K 0.442505481 1.199127844 -0.486242807 1.059459968 -0.380161871 -1.583997227 FBgn0037668 CG16736 - http://flybase.org/reports/FBgn0037668 protein_coding_gene - - - CG16736 "IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG16736 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-100f3.2, Drer\slc25a10, Drer\slc25a11" Scer\DIC1 Cele\slc-25A10 "Xtro\rangrf, Xtro\slc25a10" "Mmus\Slc25a11, Mmus\Slc25a10" "Hsap\SLC25A10, Hsap\SLC25A11" FBgn0031792 CG13983 - http://flybase.org/reports/FBgn0031792 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG13983 - CG13983 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary,trichogen cell" DRSC02315 K 0.003721968 -0.20044766 0.287670762 0.489890641 1.53554137 0.335697266 FBgn0084286 Rst(1b)Cyr Resistance 1b Cyromazine http://flybase.org/reports/FBgn0084286 gene - - - Rst(1b)Cyr - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant,partially" FBgn0060670 l(3)S079101 lethal (3) S079101 http://flybase.org/reports/FBgn0060670 gene - - - "0791/01, l(3)S079101" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262401 mir-285 mir-285 stem loop http://flybase.org/reports/FBgn0262401 miRNA_gene - - - "dme-mir-285, miR-285, mir-285, CR42941, CR33601" - CR42941 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal" wing FBgn0266694 CR45184 - http://flybase.org/reports/FBgn0266694 non_protein_coding_gene - - - CR45184 - CR45184 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034898 CG18128 - http://flybase.org/reports/FBgn0034898 protein_coding_gene purine-nucleoside phosphorylase activity ; GO:0004731 | inferred from electronic annotation with InterPro:IPR011268 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 - CG18128 "IPR000845:Nucleoside phosphorylase domain, IPR011268:Purine nucleoside phosphorylase" CG18128 11-Aug-17 DroID_v2017_08 "Drer\pnp5a, Drer\pnp5b, Drer\pnp4b, Drer\pnp4a, Drer\pnp6" Scer\PNP1 Cele\K02D7.1 Xtro\pnp "Mmus\Pnp, Mmus\Pnp2" Hsap\PNP "partially lethal - majority die,visible" mesothoracic tergum FBgn0085564 CG41234 - http://flybase.org/reports/FBgn0085564 protein_coding_gene - - - CG41234 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039677 ppk30 pickpocket 30 http://flybase.org/reports/FBgn0039677 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG18110, ppk30" IPR001873:Epithelial sodium channel CG18110 11-Aug-17 DroID_v2017_08 "Drer\asic1c, Drer\asic4a, Drer\asic4b, Drer\asic1a, Drer\asic1b, Drer\asic2" - "Cele\delm-2, Cele\del-5, Cele\acd-2, Cele\acd-4, Cele\acd-5, Cele\acd-1, Cele\flr-1, Cele\delm-1, Cele\del-9" "Xtro\asic5, Xtro\scnn1g, Xtro\scnn1b, Xtro\asic4, Xtro\scnn1a, Xtro\asic1, Xtro\scnn1d" "Mmus\Scnn1g, Mmus\Asic2, Mmus\Asic4, Mmus\Scnn1b, Mmus\Asic1, Mmus\Scnn1a, Mmus\Asic5, Mmus\Asic3" "Hsap\ASIC2, Hsap\ASIC1, Hsap\SCNN1G, Hsap\ASIC3, Hsap\SCNN1B, Hsap\SCNN1A, Hsap\ASIC5, Hsap\SCNN1D, Hsap\ASIC4" "viable,lethal" FBgn0003547 su(Bar) suppressor of Bar http://flybase.org/reports/FBgn0003547 - gene - - - "m(B), M(B), su(B), su(Bar)" - - 11-Aug-17 DroID_v2017_08 - - - - - - ommatidium FBgn0058307 CG40307 - http://flybase.org/reports/FBgn0058307 protein_coding_gene - - - CG40307 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028199 l(3)S020114 lethal (3) S020114 http://flybase.org/reports/FBgn0028199 gene - - - "0201/14, l(3)S020114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0034918 Pym Partner of Y14 and Mago http://flybase.org/reports/FBgn0034918 protein_coding_gene exon-exon junction complex binding ; GO:1990448 | inferred from physical interaction with mago inferred from physical interaction with tsu ribosomal small subunit binding ; GO:0043024 | NOT inferred from direct assay inferred from physical interaction with RpL32 inferred from physical interaction with RpS6 RNA binding ; GO:0003723 | inferred from direct assay eukaryotic initiation factor 4G binding ; GO:0031370 | NOT inferred from physical interaction with eIF4G1 eukaryotic initiation factor 4E binding ; GO:0008190 | NOT inferred from physical interaction with eIF4E1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P49028 inferred from physical interaction with UniProtKB:Q9V535 "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from sequence or structural similarity with UniProtKB:Q9BRP8 exon-exon junction complex disassembly ; GO:1903259 | inferred from mutant phenotype cap-dependent translational initiation ; GO:0002191 | NOT inferred from physical interaction with Cbp20 inferred from physical interaction with pAbp" exon-exon junction complex ; GO:0035145 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Pym, UD3, CG10330, CG30176, BEST:HL05757, wibg, PYM, pym, Wibg" IPR015362:WIBG family CG30176 11-Aug-17 DroID_v2017_08 Drer\pym1 - Cele\T20G5.9 Xtro\pym1 Mmus\Pym1 Hsap\PYM1 "female fertile,female semi-sterile,grandchildless,viable,lethal,recessive" ovary FBgn0284248 Cyt-c-p Cytochrome c proximal http://flybase.org/reports/FBgn0284248 protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR002327, InterPro:IPR009056 electron carrier activity ; GO:0009055 | inferred from direct assay" oxidative phosphorylation ; GO:0006119 | inferred from sequence or structural similarity with SGD:S000003809 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with SGD:S000003809 cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "Cyt-c-p, l(2)k13905, CG17903, cytC-p, cyt-c-p, cytochrome c, Cyt-c2, Cytc, cyt-c2, cyt.c, DC4, DMc01, pDMc01, CytC-2, Cytc-p, dc4, cyt c-p, Cyct-c-p, cyt c, Cyt c, CytC, Cyt C, dCyt.C-p, CYC" "IPR002327:Cytochrome c, class IA/ IB, IPR009056:Cytochrome c-like domain" CG17903 11-Aug-17 DroID_v2017_08 Drer\cycsb "Scer\CYC1, Scer\CYC7" "Cele\cyc-2.2, Cele\cyc-2.1" "Xtro\cycs, Xtro\cyct" "Mmus\Cycs, Mmus\Cyct" Hsap\CYCS " adult stage , larval stage--adult stage " " adult thorax

, adult head

, adult abdomen

" "lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible" "trichogen cell,mesothoracic tergum" FBgn0086662 snoRNA:Psi28S-3186 snoRNA:Psi28S-3186 http://flybase.org/reports/FBgn0086662 snoRNA_gene - - - "snoRNA:165, psi28s-3186, Dm-165, snoR165, CR33709, Psi 28S-3186(SnoR165), snoRNA:Psi28S-3186, psi-28S-3168, pug28S-3186" - CR33709 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0087012 5-HT2A 5-hydroxytryptamine (serotonin) receptor 2A http://flybase.org/reports/FBgn0087012 protein_coding_gene G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from direct assay neurotransmitter receptor activity ; GO:0030594 | inferred from biological aspect of ancestor with PANTHER:PTN000664111 G-protein coupled serotonin receptor activity ; GO:0004993 | traceable author statement Gq/11-coupled serotonin receptor activity ; GO:0001587 | non-traceable author statement G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from sequence or structural similarity serotonin receptor signaling pathway ; GO:0007210 | traceable author statement serotonin receptor signaling pathway ; GO:0007210 | inferred from sequence or structural similarity germ-band extension ; GO:0007377 | inferred from mutant phenotype serotonin receptor signaling pathway ; GO:0007210 | inferred from direct assay inferred from mutant phenotype positive regulation of feeding behavior ; GO:2000253 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "l(3)82CDb, 5-HT[[2Dro]], 5-HT2Dro, Dm5HT2, 5HT2-Dro, 5HT[[2Dro]], 5-ht2Dro, 5HT2Dro, 5-HT[[2]], 5HT-dro[[1]], CG1056, 5HT-R82A, d5-HT2, 5-HT[[2]]Dro, 5-HT2, 5-HT[2]Dro, 5HT2, 5-HT2A, d5-HT2A, 5HT2a" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG1056 11-Aug-17 DroID_v2017_08 "Drer\gpr27, Drer\htr2b, Drer\htr2cl1, Drer\gpr85, Drer\gpr173, Drer\htr2aa, Drer\htr2ab, Drer\htr2cl2" - "Cele\ser-1, Cele\ser-2" "Xtro\htr2c, Xtro\gpr85, Xtro\gpr173" "Mmus\Gpr173, Mmus\Htr2b, Mmus\Gpr27, Mmus\Htr2a, Mmus\Gpr85, Mmus\Htr2c" "Hsap\GPR173, Hsap\GPR85, Hsap\HTR2A, Hsap\HTR2C, Hsap\HTR2B, Hsap\GPR27" " embryonic stage | stage 5 , embryonic stage | stage >=13 " " organism | even pair rule

, central nervous system | restricted

" FBgn0004903 Rb97D Ribonuclear protein at 97D http://flybase.org/reports/FBgn0004903 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity spermatid development ; GO:0007286 | inferred from mutant phenotype - "rbf, Rb97D1, ms(3)03445, R16, Hrb97D, CG6354, Rb97D, rb97d, RBP97D" IPR000504:RNA recognition motif domain CG6354 11-Aug-17 DroID_v2017_08 "Drer\hnrnpa1a, Drer\msi2b, Drer\rbm24a, Drer\srsf10a, Drer\syncripl, Drer\trnau1apb, Drer\raly, Drer\ncl, Drer\trnau1apa, Drer\rbm24b, Drer\msi2a, Drer\hnrpdl, Drer\hnrnpa1b, Drer\dazap1, Drer\dazl, Drer\hnrnpa3, Drer\eif4ba, Drer\zcrb1, Drer\cirbpa, Drer\hnrnpd, Drer\syncrip, Drer\hnrnpa0l, Drer\zgc:55733, Drer\hnrnpa0b, Drer\eif4h, Drer\hnrnpa0a, Drer\hnrnpabb, Drer\hnrnpc, Drer\hnrnpaba, Drer\ncoa5, Drer\wu:fq32h04, Drer\rbm34" "Scer\CWC2, Scer\NGR1, Scer\MRN1, Scer\NOP6, Scer\MUD1, Scer\NAM8, Scer\HRP1, Scer\NAB6, Scer\NOP12" "Cele\sqd-1, Cele\H28G03.1, Cele\msi-1, Cele\hrp-1" "Xtro\ralyl, Xtro\trnau1ap, Xtro\rbm34, Xtro\raly, Xtro\hnrnpdl, Xtro\hnrnpa1, Xtro\hnrnpa0, Xtro\dazap1, Xtro\hnrnpa3, Xtro\hnrnpab, Xtro\hnrnpc, Xtro\hnrnpa2b1, Xtro\cirbp, Xtro\dazl, Xtro\eif4h, Xtro\eif4b, Xtro\hnrnpd, Xtro\msi1" "Mmus\Hnrnpab, Mmus\Rbm38, Mmus\Dazap1, Mmus\Eif4h, Mmus\Boll, Mmus\Ncl, Mmus\Rbm31y, Mmus\Hnrnpa0, Mmus\Tra2b, Mmus\Hnrnpa3, Mmus\Srsf12, Mmus\Hnrnpd, Mmus\Rbm34, Mmus\Zcrb1, Mmus\Cirbp, Mmus\Msi1, Mmus\Eif4b, Mmus\Trnau1ap, Mmus\Syncrip, Mmus\Rbm24, Mmus\Msi2, Mmus\Dazl, Mmus\Hnrnpa2b1, Mmus\Srsf10, Mmus\Gm21379, Mmus\Hnrnpc, Mmus\Raly, Mmus\Slirp, Mmus\Hnrnpa1, Mmus\Hnrnpr, Mmus\Hnrnpdl" "Hsap\RBM34, Hsap\BOLL, Hsap\DAZAP1, Hsap\NCL, Hsap\HNRNPC, Hsap\DAZ4, Hsap\HNRNPA3, Hsap\RALY, Hsap\DAZ1, Hsap\DAZ2, Hsap\SLIRP, Hsap\RBM24, Hsap\RBMXL3, Hsap\HNRNPD, Hsap\EIF4H, Hsap\TRNAU1AP, Hsap\MSI2, Hsap\HNRNPA1L2, Hsap\CIRBP, Hsap\EIF4B, Hsap\RBM3, Hsap\HNRNPR, Hsap\HNRNPDL, Hsap\DAZ3, Hsap\MSI1, Hsap\SYNCRIP, Hsap\SRSF10, Hsap\HNRNPA0, Hsap\DAZL, Hsap\RALYL, Hsap\HNRNPA2B1, Hsap\HNRNPAB, Hsap\HNRNPA1, Hsap\HNRNPCL1, Hsap\RBM38" embryonic stage -- adult stage "male sterile,recessive" "nucleus & spermatid,axoneme" FBgn0000148 aw awry http://flybase.org/reports/FBgn0000148 - gene - - - aw - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,fertile" wing FBgn0065590 l(2)SH0905 lethal (2) SH0905 http://flybase.org/reports/FBgn0065590 gene - - - "l(2)SH0905, l(2)SH2 0905" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005402 l(1)10Bn lethal (1) 10Bn http://flybase.org/reports/FBgn0005402 - gene - - - "l(1)C248, l(1)L19, l(1)10Bn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0016800 l(1)K1 lethal (1) K1 http://flybase.org/reports/FBgn0016800 - gene - - - "l(1)K1, K1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262962 CG43273 - http://flybase.org/reports/FBgn0262962 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43273 - CG43273 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031255 BBS8 Bardet-Biedl syndrome 8 http://flybase.org/reports/FBgn0031255 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern cilium ; GO:0005929 | inferred from sequence or structural similarity with HGNC:20087 BBSome ; GO:0034464 | inferred from sequence or structural similarity with HGNC:20087 cilium ; GO:0005929 | inferred by curator from GO:0060271 "BBS2, CG13691, BBS8" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG13691 11-Aug-17 DroID_v2017_08 Drer\ttc8 Scer\CDC27 Cele\bbs-8 Xtro\ttc8 Mmus\Ttc8 Hsap\TTC8 viable FBgn0020879 anon-43Ba anon-43Ba http://flybase.org/reports/FBgn0020879 - gene - - - "tuII, anon-43Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013536 l(2)ry36 lethal (2) ry36 http://flybase.org/reports/FBgn0013536 - gene - - - "l(2)36, l(2)ry36" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0283484 CLIP-190::Rnor\Clip1 - http://flybase.org/reports/FBgn0283484 engineered_fusion_gene - - - CLIP-190::Rnor\Clip1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260340 GSd424 - http://flybase.org/reports/FBgn0260340 gene - - - GSd424 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0046707 GIIIE GIIIE http://flybase.org/reports/FBgn0046707 gene phospholipase A2 activity ; GO:0004623 | non-traceable author statement - extracellular region ; GO:0005576 | non-traceable author statement "dGIIIE, GIIIE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042135 CG18812 - http://flybase.org/reports/FBgn0042135 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12040, CG18813, CG18812" "IPR001251:CRAL-TRIO lipid binding domain, IPR002589:Macro domain" CG18812 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-219a4.6, Drer\macrod1, Drer\LOC100148704, Drer\gdap2, Drer\macrod2, Drer\si:ch211-219a4.3, Drer\h2afy2" - Cele\B0035.3 "Xtro\parp14.2, Xtro\gdap2, Xtro\h2afy, Xtro\parp9, Xtro\h2afy2" "Mmus\Parp14, Mmus\Macrod2, Mmus\Macrod1, Mmus\Gdap2, Mmus\Parp9, Mmus\H2afy2, Mmus\H2afy" "Hsap\H2AFY, Hsap\PARP14, Hsap\GDAP2, Hsap\PARP9, Hsap\PARP15, Hsap\MACROD2, Hsap\H2AFY2, Hsap\MACROD1" viable FBgn0038887 CG7907 - http://flybase.org/reports/FBgn0038887 protein_coding_gene RNA cap binding ; GO:0000339 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 "mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from electronic annotation with InterPro:IPR027159 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004732 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 primary miRNA processing ; GO:0031053 | inferred from biological aspect of ancestor with PANTHER:PTN000275634" mRNA cap binding complex ; GO:0005845 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 nuclear cap binding complex ; GO:0005846 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 intracellular ribonucleoprotein complex ; GO:0030529 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 CG7907 "IPR003890:MIF4G-like, type 3, IPR015172:MIF4G-like, type 1, IPR015174:MIF4G-like, type 2, IPR027159:Nuclear cap-binding protein subunit 1, IPR016024:Armadillo-type fold" CG7907 11-Aug-17 DroID_v2017_08 - Scer\STO1 Cele\ncbp-1 Xtro\ncbp1 Mmus\Ncbp1 Hsap\NCBP1 FBgn0032381 Mal-B1 Maltase B1 http://flybase.org/reports/FBgn0032381 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "Mal-B1, CG14934, mal_B1, Drome_B1" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG14934 11-Aug-17 DroID_v2017_08 "Drer\slc3a2a, Drer\zgc:158423, Drer\slc3a1, Drer\slc3a2b, Drer\si:dkey-202g17.3" "Scer\IMA5, Scer\IMA4, Scer\IMA1, Scer\IMA2, Scer\MAL32, Scer\MAL12, Scer\IMA3" "Cele\atgp-1, Cele\atgp-2" "Xtro\slc3a1, Xtro\slc3a2" "Mmus\Slc3a2, Mmus\Slc3a1" "Hsap\SLC3A2, Hsap\SLC3A1" viable DRSC02416 EK -0.704395479 0.714998552 3.899972179 0.729753206 -2.763082872 0.436859503 FBgn0003681 ten tenuis chaetae http://flybase.org/reports/FBgn0003681 - gene - - - ten - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile" macrochaeta FBgn0028226 l(3)S005302a lethal (3) S005302a http://flybase.org/reports/FBgn0028226 gene - - - "0053/02, l(3)S005302, l(3)S005302a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030385 Ir11a Ionotropic receptor 11a http://flybase.org/reports/FBgn0030385 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model sensory perception of taste ; GO:0050909 | inferred from expression pattern detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir11a, CT35969, CG15732, DmelIR11a, IR11a, Q9VYN4_DROME" IPR001638:Solute-binding protein family 3/N-terminal domain of MltF CG15732 11-Aug-17 DroID_v2017_08 "Drer\grid1b, Drer\grid1a, Drer\LOC100537813" - "Cele\glr-5, Cele\glr-8, Cele\glr-7" - "Mmus\Grik4, Mmus\Grid1" "Hsap\GRID2, Hsap\GRID1, Hsap\GRIK3, Hsap\GRIN2C" "viable,lethal" FBgn0044000 Su(rst)C40 Su(rst)C40 http://flybase.org/reports/FBgn0044000 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C40, Su(rst)C40" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060658 l(3)S082807 lethal (3) S082807 http://flybase.org/reports/FBgn0060658 gene - - - "0828/07, l(3)S082807" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0029036 l(2)N36 lethal (2) N36 http://flybase.org/reports/FBgn0029036 gene - - - "N36, l(2)N36" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259194 Ir94e Ionotropic receptor 94e http://flybase.org/reports/FBgn0259194 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG17379, DmelIR94e, Ir94e, IR94e, CG42298" - CG42298 11-Aug-17 DroID_v2017_08 - - Cele\glr-7 - - - viable FBgn0000833 fs(1)M15 female sterile (1) M15 http://flybase.org/reports/FBgn0000833 - gene - - - fs(1)M15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,rescuable maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0015921 cleo cleopatra http://flybase.org/reports/FBgn0015921 - gene - - - cleo - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile" embryonic/larval brain FBgn0058211 CG40211 - http://flybase.org/reports/FBgn0058211 protein_coding_gene - - - CG40211 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014401 tru troupa http://flybase.org/reports/FBgn0014401 - gene - - - tru - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261019 moi modigliani http://flybase.org/reports/FBgn0261019 protein_coding_gene single-stranded telomeric DNA binding ; GO:0043047 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95RV2 "telomere capping ; GO:0016233 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred by curator from GO:0000782,GO:0043047 protection from non-homologous end joining at telomere ; GO:0031848 | inferred from mutant phenotype inferred from genetic interaction with mei-41 inferred from genetic interaction with tefu" "polytene chromosome interband ; GO:0005705 | inferred from direct assay telomere cap complex ; GO:0000782 | inferred from direct assay chromosome, telomeric region ; GO:0000781 | inferred from direct assay" "moi, l(3)S096713, 0967/13, Dromel_CG31241_FBtr0083570_dtl_uORF, tlu, Dtl uORF, DTLu, CG42350, l(3)CB02140, CG31241, DTL, uORF, DTL/Moi, Moi" - CG42350 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045487 Gr36a Gustatory receptor 36a http://flybase.org/reports/FBgn0045487 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "CG31747, GrLU1, Gr36B1, LU.1, GRLU.1, Gr36a, GR36a" IPR013604:7TM chemoreceptor CG31747 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0015369 bushy bushy http://flybase.org/reports/FBgn0015369 - gene - - - "bsh, bushy" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032105 borr borealin-related http://flybase.org/reports/FBgn0032105 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with shrb DNA binding ; GO:0003677 | inferred from direct assay "mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from biological aspect of ancestor with PANTHER:PTN001815752 mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype histone phosphorylation ; GO:0016572 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype" spindle midzone ; GO:0051233 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay chromosome passenger complex ; GO:0032133 | inferred from direct assay meiotic spindle midzone ; GO:1990385 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay "CG4454, Bor, dBor, borr, Borr, BORR" IPR018867:Cell division protein borealin CG4454 11-Aug-17 DroID_v2017_08 "Drer\cdca8, Drer\cdca9" - - "Xtro\cdca9, Xtro\cdca8" Mmus\Cdca8 Hsap\CDCA8 "mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage,increased cell death,somatic clone,cell size defective,Minute,viable,lethal - all die before end of embryonic stage,some die during embryonic stage" "chromatin,trichogen cell,mesothoracic tergum,ventral nerve cord & nucleus,brain & nucleus,nucleus | somatic clone,spindle | somatic clone,leg,somatic clone,eye,wing,wing hair,ectopic,wing margin bristle" FBgn0060671 l(3)S078709 lethal (3) S078709 http://flybase.org/reports/FBgn0060671 gene - - - "0787/09, l(3)S078709" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265904 CR44693 - http://flybase.org/reports/FBgn0265904 non_protein_coding_gene - - - CR44693 - CR44693 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037376 Hat1 Histone acetyltransferase 1 http://flybase.org/reports/FBgn0037376 protein_coding_gene histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000248102 H4 histone acetyltransferase activity ; GO:0010485 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from electronic annotation with InterPro:IPR017380 chromatin silencing at telomere ; GO:0006348 | inferred from electronic annotation with InterPro:IPR017380 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype CENP-A containing nucleosome assembly ; GO:0034080 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000248102 "dmHAG409, CG2051, Hat1" "IPR016181:Acyl-CoA N-acyltransferase, IPR017380:Histone acetyltransferase type B, catalytic subunit, IPR019467:Histone acetyl transferase HAT1 N-terminal" CG2051 11-Aug-17 DroID_v2017_08 Drer\hat1 Scer\HAT1 Cele\hat-1 Xtro\hat1 Mmus\Hat1 Hsap\HAT1 viable FBgn0044477 EP1016 EP1016 http://flybase.org/reports/FBgn0044477 gene - - - EP1016 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0069917 CG41135 - http://flybase.org/reports/FBgn0069917 protein_coding_gene - - - CG41135 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031946 CG7164 - http://flybase.org/reports/FBgn0031946 protein_coding_gene - - - "CG7164, Q9VLX3" - CG7164 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263131 CG43373 - http://flybase.org/reports/FBgn0263131 protein_coding_gene adenylate cyclase activity ; GO:0004016 | inferred from electronic annotation with InterPro:IPR009398 adenylate cyclase activity ; GO:0004016 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "cAMP biosynthetic process ; GO:0006171 | inferred from electronic annotation with InterPro:IPR009398 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG43373, CG12436, CG32158, AC, CG42513, Ago2" "IPR029787:Nucleotide cyclase, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR009398:Adenylate cyclase, conserved domain, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR032628:Adenylate cyclase, N-terminal" CG43373 11-Aug-17 DroID_v2017_08 "Drer\adcy6a, Drer\adcy6b, Drer\adcy1b, Drer\adcy2a, Drer\si:ch211-132f19.7, Drer\adcy5, Drer\si:dkey-206f10.1, Drer\adcy1a, Drer\adcy3a, Drer\adcy8, Drer\adcy2b, Drer\adcy7" - "Cele\acy-2, Cele\acy-4" "Xtro\adcy6, Xtro\adcy7, Xtro\dnajc27, Xtro\adcy1, Xtro\adcy4" "Mmus\Adcy1, Mmus\Adcy7, Mmus\Adcy6, Mmus\Adcy2, Mmus\Adcy4, Mmus\Adcy3, Mmus\Adcy8, Mmus\Adcy5" "Hsap\ADCY2, Hsap\ADCY1, Hsap\ADCY8, Hsap\ADCY7, Hsap\ADCY6, Hsap\ADCY4, Hsap\ADCY3, Hsap\ADCY5" FBgn0036246 CG17154 - http://flybase.org/reports/FBgn0036246 protein_coding_gene - - - CG17154 - CG17154 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014891 Wedge Wedge http://flybase.org/reports/FBgn0014891 - gene - - - Wedge - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye FBgn0029121 Sras severas http://flybase.org/reports/FBgn0029121 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000316030 metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000316030 CAAX-box protein processing ; GO:0071586 | inferred from biological aspect of ancestor with PANTHER:PTN000316030 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000316030 "CG4852, Sras, FAC2_DROME" IPR003675:CAAX amino terminal protease CG4852 11-Aug-17 DroID_v2017_08 "Drer\rce1a, Drer\rce1b" Scer\RCE1 Cele\fce-2 Xtro\rce1 Mmus\Rce1 Hsap\RCE1 viable FBgn0028412 Mst33A Mst33A http://flybase.org/reports/FBgn0028412 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6541, Mst33A" IPR009071:High mobility group box domain CG6541 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267985 CR46252 - http://flybase.org/reports/FBgn0267985 non_protein_coding_gene - - - CR46252 - CR46252 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017546 Rp34 Ribosomal protein 34 http://flybase.org/reports/FBgn0017546 - gene structural constituent of ribosome ; GO:0003735 | non-traceable author statement translation ; GO:0006412 | non-traceable author statement ribosome ; GO:0005840 | non-traceable author statement "rp34, Rp34" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259623 B0531 - http://flybase.org/reports/FBgn0259623 gene - - - B0531 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0004826 fs(2)ltoHC44 female sterile (2) ltoHC44 http://flybase.org/reports/FBgn0004826 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoHC44 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0031757 Ucp4C Ucp4C http://flybase.org/reports/FBgn0031757 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 oxidative phosphorylation uncoupler activity ; GO:0017077 | inferred from sequence or structural similarity with UniProtKB:O95847 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 response to cold ; GO:0009409 | inferred from biological aspect of ancestor with PANTHER:PTN001942541 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 regulation of mitochondrial membrane potential ; GO:0051881 | inferred from biological aspect of ancestor with PANTHER:PTN001942541 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:O95847 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:O95847 "dmUCP4c, DmUCP4C, CG9064, anon-WO03061681.2, anon-WO03061681.1, anon-WO03037362.7, anon-WO0242455.4, anon-WO0242455.3, anon-WO02079478.2, anon-WO02079478.1, Ucp4C, Ucp4c, UCP4c, UCP4C, ucp4C" "IPR018108:Mitochondrial substrate/solute carrier, IPR002067:Mitochondrial carrier protein, IPR023395:Mitochondrial carrier domain" CG9064 11-Aug-17 DroID_v2017_08 "Drer\ucp1, Drer\ucp3, Drer\mrpl12, Drer\slc25a10, Drer\slc25a11, Drer\slc25a14, Drer\si:ch1073-100f3.2, Drer\slc25a27, Drer\ucp2" Scer\DIC1 "Cele\mrpl-12, Cele\slc-25A10, Cele\ucp-4" "Xtro\slc25a30, Xtro\slc25a10, Xtro\ucp2, Xtro\ucp1, Xtro\slc25a27, Xtro\rangrf" "Mmus\Mrpl12, Mmus\Ucp2, Mmus\Slc25a30, Mmus\Ucp3, Mmus\Slc25a27, Mmus\Slc25a10, Mmus\Slc25a14, Mmus\Ucp1, Mmus\Slc25a11" "Hsap\SLC25A10, Hsap\UCP1, Hsap\UCP3, Hsap\UCP2, Hsap\SLC25A14, Hsap\MRPL12, Hsap\SLC25A11, Hsap\SLC25A27, Hsap\SLC25A30" "viable,fertile" FBgn0065922 l(2)SH0153 lethal (2) SH0153 http://flybase.org/reports/FBgn0065922 gene - - - "l(2)SH0153, l(2)SH2 0153" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260612 2L2468 - http://flybase.org/reports/FBgn0260612 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2468 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "dorsal air sac primordium,somatic clone" FBgn0024920 Ts Thymidylate synthase http://flybase.org/reports/FBgn0024920 - protein_coding_gene "thymidylate synthase activity ; GO:0004799 | inferred from electronic annotation with InterPro:IPR000398, InterPro:IPR020940" "dTMP biosynthetic process ; GO:0006231 | inferred from electronic annotation with InterPro:IPR000398, InterPro:IPR020940 neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "CG3181, FBgn0024920, TS, c1.5, anon-23Ca, Ts" "IPR000398:Thymidylate synthase, IPR023451:Thymidylate synthase/dCMP hydroxymethylase domain, IPR020940:Thymidylate synthase, active site" CG3181 11-Aug-17 DroID_v2017_08 Drer\tyms Scer\CDC21 Cele\tyms-1 Xtro\tyms Mmus\Tyms Hsap\TYMS "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,trichogen cell" FBgn0005153 l(2)G94 lethal (2) G94 http://flybase.org/reports/FBgn0005153 - gene - - - l(2)G94 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032208 Ufd4 Ubiquitin fusion-degradation 4-like http://flybase.org/reports/FBgn0032208 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR010606 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12306 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:12306 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:12306 "CG5604, Ufd4" "IPR000569:HECT domain, IPR002110:Ankyrin repeat, IPR010606:Mib-herc2, IPR012919:SUN domain, IPR008979:Galactose-binding domain-like, IPR016024:Armadillo-type fold, IPR020683:Ankyrin repeat-containing domain, IPR011989:Armadillo-like helical" CG5604 11-Aug-17 DroID_v2017_08 "Drer\hectd1, Drer\trip12" Scer\UFD4 Cele\hecd-1 "Xtro\trip12, Xtro\hectd1" "Mmus\Hectd1, Mmus\Trip12" "Hsap\HECTD1, Hsap\TRIP12" "viable,visible" mesothoracic tergum FBgn0086690 Plp Pericentrin-like protein http://flybase.org/reports/FBgn0086690 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sas-4 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype microtubule nucleation ; GO:0007020 | inferred from direct assay centrosome organization ; GO:0051297 | inferred from mutant phenotype cilium-dependent cell motility ; GO:0060285 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay "Plp, D-PLP, CG6735, CG18648, CG13459, d-plp, CP309, AKAP450, l(3)s2172, CG33957, cp309, PACT, dplp, DPLP, pPlp, PLP, Cp309, dPLP, Dplp, plp" IPR019528:Pericentrin/AKAP-450 centrosomal targeting domain CG33957 11-Aug-17 DroID_v2017_08 "Drer\akap9, Drer\pcnt" Scer\SLK19 "Cele\C18C4.5, Cele\hcp-1" - "Mmus\Akap9, Mmus\Pcnt" "Hsap\PCNT, Hsap\AKAP9" FBgn0262486 CG43076 - http://flybase.org/reports/FBgn0262486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43076, lincRNA.997" - CG43076 11-Aug-17 DroID_v2017_08 Drer\tmem101 - - Xtro\tmem101 Mmus\Tmem101 Hsap\TMEM101 FBgn0011129 l(1)Q203 lethal (1) Q203 http://flybase.org/reports/FBgn0011129 FBgn0010210 gene - - - l(1)Q203 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011954 tRNA:Arg-TCG-2-2 transfer RNA:Arginine-TCG 2-2 http://flybase.org/reports/FBgn0011954 "FBgn0011947, FBgn0052526, FBgn0060078" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "CR32526, tRNA-Arg, tRNA[arg], AE002620.trna3-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002620, tRNA:arg19F, chrX.trna16-ArgTCG, tRNA-Arg-TCG-2-2, tRNA:Arg-TCG-2-2, tRNA:R:19F, CGA" - CR32526 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052282 Drsl4 Drosomycin-like 4 http://flybase.org/reports/FBgn0052282 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro4, Dro-4, CG32282, Drs-lF, dros4, dro4, dro-4, Drsl4" "IPR003614:Knottin, scorpion toxin-like" CG32282 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026573 ADD1 ADD domain-containing protein 1 http://flybase.org/reports/FBgn0026573 FBgn0033670 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from direct assay methylated histone binding ; GO:0035064 | inferred from physical interaction with His3 protein binding ; GO:0005515 | inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay pericentric heterochromatin ; GO:0005721 | inferred from direct assay "LD29214, BEST:LD29214, CG8290, ADD1, dADD1, dadd1" "IPR025766:ADD domain, IPR006578:MADF domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8290 11-Aug-17 DroID_v2017_08 "Drer\dnmt3bb.3, Drer\dnmt3ab, Drer\dnmt3bb.1, Drer\dnmt3bb.2, Drer\dnmt3aa, Drer\dnmt3ba, Drer\atrx" - Cele\xnp-1 Xtro\dnmt3a "Mmus\Atrx, Mmus\Dnmt3a, Mmus\Dnmt3b, Mmus\Dnmt3l" "Hsap\DNMT3A, Hsap\DNMT3L, Hsap\ATRX, Hsap\DNMT3B" "viable,suppressor of variegation,dominant,lethal" FBgn0065732 l(2)SH0551 lethal (2) SH0551 http://flybase.org/reports/FBgn0065732 gene - - - l(2)SH0551 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0063648 CE2-1 "Calcineurin enhancer, chromosome 2, group 1" http://flybase.org/reports/FBgn0063648 gene - - - CE2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001538 l(1)14Cb lethal (1) 14Cb http://flybase.org/reports/FBgn0001538 - gene - - - "l(1)k17a, k17a, l(1)14Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016945 tilA touch insensitive larva A http://flybase.org/reports/FBgn0016945 - gene - - - tilA - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0060561 l(3)S096805a lethal (3) S096805a http://flybase.org/reports/FBgn0060561 gene - - - "0968/05, l(3)S096805a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019763 l(1)6c-21 lethal (1) 6c-21 http://flybase.org/reports/FBgn0019763 - gene - - - l(1)6c-21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067622 LSm-4 Like Sm protein 4 http://flybase.org/reports/FBgn0067622 protein_coding_gene - "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" - "CG31990, BcDNA:SD20015, CG31990-ORFA, CG33677, LSm-4, LSm4, LSM4" IPR017920:COMM domain CG33677 11-Aug-17 DroID_v2017_08 "Drer\commd5, Drer\commd9" - Cele\T07C4.12 "Xtro\commd5, Xtro\commd9" "Mmus\Commd9, Mmus\Commd5" "Hsap\COMMD5, Hsap\COMMD9" FBgn0030098 CG12057 - http://flybase.org/reports/FBgn0030098 protein_coding_gene - - - "BcDNA:LP05863, CG12057" IPR007931:Protein of unknown function DUF725 CG12057 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033229 CG12822 - http://flybase.org/reports/FBgn0033229 protein_coding_gene - - - "CG12822, CG12822-PA" IPR023370:TsaA-like domain CG12822 11-Aug-17 DroID_v2017_08 "Drer\zgc:66475, Drer\trmo" - - Xtro\trmo Mmus\Trmo Hsap\TRMO viable FBgn0084555 bda belinda http://flybase.org/reports/FBgn0084555 gene - - - bda - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261822 Bsg Basigin http://flybase.org/reports/FBgn0261822 protein_coding_gene - single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype endoplasmic reticulum localization ; GO:0051643 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype nucleus localization ; GO:0051647 | inferred from mutant phenotype mitochondrion localization ; GO:0051646 | inferred from mutant phenotype cytoskeleton of presynaptic active zone ; GO:0048788 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from mutant phenotype "Bsg, NP6293, bsg, CG31605, gel, 135/10, l(2)06243, l(2)k13638, l(2)k09030, l(2)k06338, ms(2)08318, BcDNA:GH21853, l(2)k14308, l(2)SH1217, l(2)SH2 1217" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG31605 11-Aug-17 DroID_v2017_08 "Drer\vstm2l, Drer\bsg, Drer\nptnb, Drer\nptna, Drer\si:ch211-261c8.5" - "Cele\zig-1, Cele\zig-7, Cele\zig-11" "Xtro\bsg, Xtro\nptn, Xtro\emb" "Mmus\Bsg, Mmus\Vstm2l, Mmus\Nptn, Mmus\Emb" "Hsap\VSTM2L, Hsap\EMB, Hsap\BSG, Hsap\TMIGD1, Hsap\NPTN" FBgn0266306 CR44971 - http://flybase.org/reports/FBgn0266306 non_protein_coding_gene - - - CR44971 - CR44971 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263762 CG43679 - http://flybase.org/reports/FBgn0263762 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43679 - CG43679 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029504 CHES-1-like Checkpoint suppressor 1-like http://flybase.org/reports/FBgn0029504 protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456 mitotic G1 DNA damage checkpoint ; GO:0031571 | inferred from genetic interaction with Mnn1 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype regulation of cell division ; GO:0051302 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "anon-EST:Posey7, CG12690, Dmches-1, ches1, CHES-1-like, Ches-1-like, FoxN, Ches1" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR018122:Fork head domain conserved site1, IPR015943:WD40/YVTN repeat-like-containing domain, IPR030456:Fork head domain conserved site 2" CG12690 11-Aug-17 DroID_v2017_08 "Drer\foxn2a, Drer\ches1, Drer\foxm1, Drer\si:ch211-145o7.3, Drer\foxn2b, Drer\foxj3, Drer\foxj2, Drer\foxn3" "Scer\FKH2, Scer\FKH1, Scer\FHL1, Scer\HCM1" "Cele\pes-1, Cele\fkh-8" "Xtro\foxn3, Xtro\foxn2" "Mmus\Foxp1, Mmus\Foxj3, Mmus\Foxp2, Mmus\Foxm1, Mmus\Foxn2, Mmus\Foxp4, Mmus\Foxj2, Mmus\Foxn3" "Hsap\FOXP4, Hsap\FOXM1, Hsap\FOXJ2, Hsap\FOXN3, Hsap\FOXN2, Hsap\FOXP1, Hsap\FOXJ3, Hsap\FOXP2" "increased cell death,visible,lethal - all die before end of pupal stage,some die during pupal stage" "heart primordium,eye,embryonic/larval cardial cell,embryonic/larval pericardial cell" DRSC18447 E -0.214597937 -0.6701924 -0.225185765 1.860905836 -0.53349305 -0.051556223 FBgn0052504 CG32504 - http://flybase.org/reports/FBgn0052504 protein_coding_gene - - - CG32504 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22745 K 0.438939617 0.400901782 0.122521301 0.110423734 -1.225817522 -1.712639293 FBgn0060436 l(3)S125012b lethal (3) S125012b http://flybase.org/reports/FBgn0060436 gene - - - "1250/12, l(3)S125012b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005267 l(3)SG87 lethal (3) SG87 http://flybase.org/reports/FBgn0005267 - gene - - - l(3)SG87 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026263 bip1 bip1 http://flybase.org/reports/FBgn0026263 FBgn0062148 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612 POZ domain binding ; GO:0031208 | inferred from physical interaction with bab1 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "bip-I, CG7574, anon-WO0118547.246, bip1, Bip1" "IPR006612:Zinc finger, C2CH-type" CG7574 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile" FBgn0085356 CG34327 - http://flybase.org/reports/FBgn0085356 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34327 - CG34327 11-Aug-17 DroID_v2017_08 - - - - - Hsap\KRTAP5-1 FBgn0266040 CR44805 - http://flybase.org/reports/FBgn0266040 non_protein_coding_gene - - - "CR44805, lincRNA.S3687" - CR44805 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001970 Pgant35A Polypeptide N-acetylgalactosaminyltransferase 35A http://flybase.org/reports/FBgn0001970 "FBgn0027860, FBgn0032545" protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from sequence or structural similarity open tracheal system development ; GO:0007424 | inferred from mutant phenotype oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement "pgant35, CG7480, l(2)35Aa, dGalNAc-T1, pgant35A, BG:DS01068.8, GalNAc-T, l(2)br12, l35Aa, br12, A3, Pgant35A" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG7480 11-Aug-17 DroID_v2017_08 "Drer\galnt10, Drer\LOC101882942, Drer\galnt1, Drer\galnt11, Drer\galnt14, Drer\galnt7, Drer\galnt16, Drer\LOC103910015, Drer\galnt8b, Drer\wbscr17, Drer\si:ch211-15e22.3, Drer\galnt12, Drer\galnt6, Drer\galnt2, Drer\galnt13, Drer\galnt9, Drer\galnt18b, Drer\LOC100535692, Drer\LOC101886587, Drer\poc1bl, Drer\LOC100334784, Drer\galnt3, Drer\galnt8a.1, Drer\LOC568645" - "Cele\gly-3, Cele\gly-9, Cele\gly-8, Cele\gly-11, Cele\gly-7, Cele\gly-10" "Xtro\galnt4, Xtro\galnt6.1, Xtro\galnt14, Xtro\wbscr17, Xtro\galnt13, Xtro\galnt1, Xtro\galnt11, Xtro\galnt16, Xtro\galnt7, Xtro\galnt10, Xtro\galnt12, Xtro\galnt15, Xtro\galnt9, Xtro\galnt2" "Mmus\Galnt12, Mmus\Galnt14, Mmus\Galnt2, Mmus\Galntl5, Mmus\Galnt6, Mmus\Galnt5, Mmus\Galnt13, Mmus\Galnt16, Mmus\Galnt9, Mmus\Galnt10, Mmus\Galntl6, Mmus\Galnt3, Mmus\Galnt15, Mmus\Galnt4, Mmus\Galnt11, Mmus\Galnt7, Mmus\Galnt1, Mmus\Wbscr17, Mmus\Galnt18" "Hsap\GALNT8, Hsap\GALNT1, Hsap\WBSCR17, Hsap\GALNT9, Hsap\GALNT16, Hsap\GALNT6, Hsap\GALNT11, Hsap\GALNT12, Hsap\GALNT15, Hsap\GALNTL6, Hsap\GALNT7, Hsap\GALNT5, Hsap\GALNT14, Hsap\GALNT2, Hsap\GALNT3, Hsap\GALNT4, Hsap\GALNT13, Hsap\GALNTL5, Hsap\POC1B-GALNT4, Hsap\GALNT10, Hsap\GALNT18" " oogenesis stage , adult stage | female , embryonic stage | early , embryonic stage -- adult stage , embryonic stage&&larval stage&&adult stage , adult stage | male " " follicle cell

, ovary

, testis

, germline cell

" "lethal,partially lethal - majority die,wild-type,recessive,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "embryonic/larval dorsal trunk,embryonic/larval tracheal system" DRSC03557 K 1.199900284 0.133253465 0.213235553 0.229465897 1.648178344 0.595455836 FBgn0001700 l(1)ESHS21 lethal (1) ESHS21 http://flybase.org/reports/FBgn0001700 - gene - - - l(1)ESHS21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262777 Su(E1)-K - http://flybase.org/reports/FBgn0262777 gene - - - Su(E1)-K - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085609 CG41314 - http://flybase.org/reports/FBgn0085609 protein_coding_gene - - - CG41314 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038569 CG7218 - http://flybase.org/reports/FBgn0038569 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7218 IPR008010:Tapt1 family CG7218 11-Aug-17 DroID_v2017_08 "Drer\tapt1a, Drer\tapt1" Scer\EMP65 Cele\F26F2.7 Xtro\tapt1 Mmus\Tapt1 Hsap\TAPT1 viable FBgn0034007 ND-51L2 NADH dehydrogenase (ubiquinone) 51 kDa subunit-like 2 http://flybase.org/reports/FBgn0034007 protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR019575 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P49821" "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P49821" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P49821 extracellular space ; GO:0005615 | inferred from direct assay "NUBM, ND-51L2, CG8102" "IPR011538:NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain, IPR019575:NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain" CG8102 11-Aug-17 DroID_v2017_08 Drer\ndufv1 - Cele\nuo-1 Xtro\ndufv1 Mmus\Ndufv1 Hsap\NDUFV1 "viable,visible" trichogen cell FBgn0037081 barc barricade http://flybase.org/reports/FBgn0037081 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000401295 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "neurogenesis ; GO:0022008 | inferred from mutant phenotype neuron differentiation ; GO:0030182 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000401295" U2-type spliceosomal complex ; GO:0005684 | inferred from biological aspect of ancestor with PANTHER:PTN000401295 nucleus ; GO:0005634 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000401295 "Tat-SF1, cg6049, cus2, CG6049, barc" "IPR000504:RNA recognition motif domain, IPR034393:TatSF1-like, IPR034392:TatSF1-like, RNA recognition motif 1" CG6049 11-Aug-17 DroID_v2017_08 Drer\htatsf1 Scer\CUS2 Cele\Y65B4A.1 Xtro\htatsf1 Mmus\Htatsf1 Hsap\HTATSF1 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0022177 l(2)k05404 lethal (2) k05404 http://flybase.org/reports/FBgn0022177 - gene - - - l(2)k05404 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004910 Eip63F-1 Ecdysone-induced protein 63F 1 http://flybase.org/reports/FBgn0004910 FBgn0035474 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Eip63F1, Ca[2+] binding protein, E63-1, E63F, Eip63Fa, CG15855, 63F-1, Eip63F-1, eip63F-1, Eip63-1, CBP12" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG15855 11-Aug-17 DroID_v2017_08 "Drer\pvalb2, Drer\cabp5a, Drer\cabp2a, Drer\calb1, Drer\cabp2b, Drer\cabp7b, Drer\calm3a, Drer\pvalb4, Drer\calm3b, Drer\calb2a, Drer\pvalb1, Drer\pvalb6, Drer\efcab11, Drer\efcab2, Drer\tnnc1b, Drer\tnnc1a, Drer\pvalb3, Drer\cabp1b, Drer\calml4b, Drer\cabp1a, Drer\rhbdl3, Drer\si:ch211-197n1.2, Drer\calm1a, Drer\calm1b, Drer\pvalb9, Drer\caln1, Drer\calml4a, Drer\caln2, Drer\cabp5b, Drer\pvalb8, Drer\cabp4, Drer\calm2a, Drer\calm2b, Drer\efcab6, Drer\tnnc2, Drer\calb2b, Drer\scgn" "Scer\CDC31, Scer\MLC1, Scer\MLC2, Scer\CMD1" "Cele\cal-2, Cele\cmd-1, Cele\cal-1, Cele\cal-3, Cele\cal-4" "Xtro\pvalb.1, Xtro\tnnc1, Xtro\cabp7, Xtro\tnnc2, Xtro\efcab6, Xtro\calb1, Xtro\cabp4, Xtro\ocm.2, Xtro\calm1, Xtro\calml4, Xtro\calm2, Xtro\ocm, Xtro\pvalb.2, Xtro\pvalb, Xtro\pgm1, Xtro\scgn, Xtro\LOC548651" "Mmus\Caln1, Mmus\Cabp7, Mmus\Tnnc1, Mmus\Rhbdl3, Mmus\Cabp1, Mmus\Efcab7, Mmus\Calm4, Mmus\Scgn, Mmus\Calb2, Mmus\Efcab6, Mmus\Ocm, Mmus\Efcab3, Mmus\Pvalb, Mmus\Efcab9, Mmus\Calb1, Mmus\Calml4, Mmus\Tnnc2, Mmus\Cabp5, Mmus\Spata21, Mmus\1700023F06Rik, Mmus\Efcab2, Mmus\Calml3, Mmus\Calm1, Mmus\Calm5, Mmus\Cabp2, Mmus\Calm3, Mmus\Calm2, Mmus\Efcab11, Mmus\Cabp4" "Hsap\CALML5, Hsap\EFCAB9, Hsap\SPATA21, Hsap\CABP7, Hsap\CALM2, Hsap\CABP5, Hsap\PVALB, Hsap\EFCAB3, Hsap\OCM2, Hsap\CALB2, Hsap\EFCAB13, Hsap\CALML3, Hsap\CALML4, Hsap\CALML6, Hsap\RHBDL3, Hsap\CALN1, Hsap\CABP4, Hsap\CALM1, Hsap\CALM3, Hsap\CALB1, Hsap\EFCAB7, Hsap\EFCAB11, Hsap\OCM, Hsap\EFCAB2, Hsap\TNNC1, Hsap\TNNC2, Hsap\SCGN, Hsap\CABP2, Hsap\CABP1, Hsap\EFCAB6" " larval stage , pupal stage | 0-8hr , pupal stage | 32-96hr , larval stage | late , embryonic stage && larval stage , embryonic stage | late " " embryonic/larval salivary gland

, embryonic/larval fat body

, ventral nerve cord

, epidermis

, embryonic/larval midgut

, larval brain

, imaginal disc

" "oxidative stress response defective,viable,fertile" FBgn0015233 Gpdh-Psi Glycerol 3 phosphate dehydrogenase pseudogene http://flybase.org/reports/FBgn0015233 - pseudogene_attribute - - - "3' gene, Gpdh-Psi" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022379 Pt-11 Larval protein-11 http://flybase.org/reports/FBgn0022379 - gene - - - Pt-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266846 CR45308 - http://flybase.org/reports/FBgn0266846 non_protein_coding_gene - - - CR45308 - CR45308 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266758 Esyt2 Extended synaptotagmin-like protein 2 http://flybase.org/reports/FBgn0266758 protein_coding_gene calcium-dependent phospholipid binding ; GO:0005544 | inferred from sequence or structural similarity with HGNC:22211 synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity intracellular transport ; GO:0046907 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence model endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000080880 synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:22211 "Esyt2, CG6643, Tricalbin" "IPR000008:C2 domain, IPR031468:Synaptotagmin-like mitochondrial-lipid-binding domain" CG6643 11-Aug-17 DroID_v2017_08 "Drer\esyt2b, Drer\esyt1a, Drer\esyt2a, Drer\syt7b, Drer\syt7a, Drer\esyt3, Drer\pla2g4aa, Drer\pla2g4ab, Drer\esyt1b, Drer\mctp1b" "Scer\INN1, Scer\TCB3, Scer\TCB2, Scer\TCB1" "Cele\mctp-1, Cele\snt-2, Cele\esyt-2" "Xtro\esyt3, Xtro\esyt1, Xtro\pla2g4a, Xtro\mctp1, Xtro\esyt2" "Mmus\Esyt1, Mmus\Mctp1, Mmus\Esyt2, Mmus\Pla2g4a, Mmus\Esyt3" "Hsap\ESYT2, Hsap\PLA2G4A, Hsap\ESYT1, Hsap\MCTP1, Hsap\ESYT3" FBgn0030344 Nrd1 Nardilysin http://flybase.org/reports/FBgn0030344 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001431 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011237, InterPro:IPR011249 protein binding involved in protein folding ; GO:0044183 | inferred from direct assay" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001431 chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CG2025, Nrd1, dNrd1" "IPR001431:Peptidase M16, zinc-binding site, IPR007863:Peptidase M16, C-terminal, IPR011765:Peptidase M16, N-terminal, IPR011249:Metalloenzyme, LuxS/M16 peptidase-like, IPR032632:Peptidase M16, middle/third domain" CG2025 11-Aug-17 DroID_v2017_08 "Drer\nrd1a, Drer\nrd1b, Drer\ide" "Scer\STE23, Scer\AXL1" "Cele\Y70C5C.1, Cele\C02G6.1, Cele\C28F5.4, Cele\F44E7.4, Cele\C02G6.2" Xtro\nrdc "Mmus\Ide, Mmus\Nrd1" "Hsap\NRDC, Hsap\IDE" "lethal,recessive,viable" FBgn0261502 CG42650 - http://flybase.org/reports/FBgn0261502 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42650, DMG4-MB6.chr3R.6.014" IPR032004:Protein of unknown function DUF4790 CG42650 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051527 CG31527 - http://flybase.org/reports/FBgn0051527 protein_coding_gene - - - CG31527 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001852 l(1)tsUC13 lethal (1) tsUC13 http://flybase.org/reports/FBgn0001852 - gene - - - l(1)tsUC13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0031361 CG17652 - http://flybase.org/reports/FBgn0031361 protein_coding_gene small ribosomal subunit rRNA binding ; GO:0070181 | inferred from biological aspect of ancestor with PANTHER:PTN000275941 "phagocytosis ; GO:0006909 | inferred from mutant phenotype maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000275941" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000275941 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000275941 CG17652 "IPR006984:rRNA-processing protein Fcf1/Utp23, IPR029060:PIN domain-like" CG17652 11-Aug-17 DroID_v2017_08 "Drer\utp23, Drer\anapc13" Scer\UTP23 Cele\C34E10.10 "Xtro\utp23, Xtro\anapc13.1" "Mmus\Utp23, Mmus\Anapc13" "Hsap\UTP23, Hsap\ANAPC13" FBgn0011044 l(1)Stark-c lethal (1) of Stark c http://flybase.org/reports/FBgn0011044 FBgn0010212 gene - - - "l(1)Stark-c, l(1)Sc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029661 CG16781 - http://flybase.org/reports/FBgn0029661 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:26025 zinc ion binding ; GO:0008270 | inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:26025 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with HGNC:26025 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with HGNC:26025 CG16781 "IPR011016:Zinc finger, RING-CH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033275:E3 ubiquitin-protein ligase MARCH-like" CG16781 11-Aug-17 DroID_v2017_08 "Drer\march5, Drer\march5l" - Cele\M110.3 Xtro\march5 Mmus\March5 Hsap\MARCH5 viable FBgn0039992 CG12416 - http://flybase.org/reports/FBgn0039992 protein_coding_gene - - - CG12416 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004932 a(1)HM27 abnormal abdomen HM27 http://flybase.org/reports/FBgn0004932 - gene - - - "l(1)HM27, a(1)HM27" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,cold sensitive" "tergite,sternite" FBgn0010615 l(2)06253 lethal (2) 06253 http://flybase.org/reports/FBgn0010615 - gene - - - l(2)06253 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037003 CG18281 - http://flybase.org/reports/FBgn0037003 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG18281 "IPR001958:Tetracycline resistance protein TetA/multidrug resistance protein MdtG, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG18281 11-Aug-17 DroID_v2017_08 "Drer\LOC557306, Drer\hiat1b, Drer\si:ch211-87m7.2, Drer\si:dkey-5g14.1, Drer\zgc:174356, Drer\hiat1a, Drer\slc46a3, Drer\si:ch211-262i1.4" Scer\YJL163C "Cele\T25D3.4, Cele\Y71G12B.25" "Xtro\mfsd14a, Xtro\mfsd14b" "Mmus\Mfsd14b, Mmus\Slc46a3, Mmus\Slc46a1, Mmus\Mfsd14a" "Hsap\SLC46A1, Hsap\MFSD14B, Hsap\SLC46A3, Hsap\MFSD14A" FBgn0050202 tRNA:Ser-TGA-2-1 transfer RNA:Serine-TGA 2-1 http://flybase.org/reports/FBgn0050202 tRNA_gene UCA codon-amino acid adaptor activity ; GO:0033407 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033407 cytosol ; GO:0005829 | inferred by curator from GO:0033407 "CR30202, AE002575.trna4-SerTGA, tRNA:S:TGA:AE002575-a, tRNA[[Ser]], chr2R.trna48-SerTGA, tRNA-Ser-TGA-2-1, tRNA:Ser-TGA-2-1, tRNA:CR30202, UCA" - CR30202 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041842 E(Sev-CycE)E19 E(Sev-CycE)E19 http://flybase.org/reports/FBgn0041842 gene - - - E(Sev-CycE)E19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266501 s-251 - http://flybase.org/reports/FBgn0266501 gene - - - s-251 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063916 McClintock\gag McClintock element gag http://flybase.org/reports/FBgn0063916 transposable_element_gene - - - McClintock\gag - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058043 CG40043 - http://flybase.org/reports/FBgn0058043 protein_coding_gene - - - CG40043 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039145 CG6000 - http://flybase.org/reports/FBgn0039145 protein_coding_gene - - - "BcDNA:RE30346, CG6000" IPR001763:Rhodanese-like domain CG6000 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-22i16.9, Drer\si:ch211-161h7.8, Drer\LOC561325, Drer\si:dkey-34l15.1, Drer\si:dkey-165n16.1" "Scer\RDL2, Scer\RDL1" - - "Mmus\Tstd1, Mmus\Tstd3" "Hsap\TSTD3, Hsap\TSTD1" viable FBgn0062593 Mod(var)1551 Mod(var)1551 http://flybase.org/reports/FBgn0062593 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1551, Mod(var)1551" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,lethal" FBgn0001192 hi high http://flybase.org/reports/FBgn0001192 - gene - - - hi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001643 l(1)dn23 lethal (1) discs normal 23 http://flybase.org/reports/FBgn0001643 - gene - - - "l(1)d.norm.-23, l(1)dn23" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267102 CR45542 - http://flybase.org/reports/FBgn0267102 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR45542 - CR45542 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263035 CG43330 - http://flybase.org/reports/FBgn0263035 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43330, CG12377" - CG43330 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002369 l(3)91Fa lethal (3) 91Fa http://flybase.org/reports/FBgn0002369 FBgn0002375 gene - - - "C2, l(3)C2, l(3)BE44, l(3)BE43, l(3)BE42, l(3)BE41, l(3)BE40, l(3)91Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022951 36w 36w http://flybase.org/reports/FBgn0022951 - gene - - - 36w - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,partially" FBgn0033320 CG8586 - http://flybase.org/reports/FBgn0033320 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" extracellular region ; GO:0005576 | inferred from direct assay "CG8586, SPH58, c-SPH58" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG8586 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Egfbp2, Mmus\Klk1b27, Mmus\Klk1b11, Mmus\Klk1b5, Mmus\Klk1b16, Mmus\Klk11, Mmus\F11, Mmus\Klk1b8, Mmus\Klk1b22, Mmus\Klk1b26, Mmus\Klk1b1, Mmus\Klk1b4, Mmus\Klk1b3, Mmus\Klkb1, Mmus\Klk1b21, Mmus\Klk1b9, Mmus\Klk1, Mmus\4930519F16Rik, Mmus\Klk1b24" "Hsap\F11, Hsap\KLK1, Hsap\KLK3, Hsap\KLK2, Hsap\KLKB1, Hsap\KLK11" viable FBgn0060988 l(3)S027821b lethal (3) S027821b http://flybase.org/reports/FBgn0060988 gene - - - "0278/21, l(3)S027821b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011826 Pp2B-14D Protein phosphatase 2B at 14D http://flybase.org/reports/FBgn0011826 "FBgn0005782, FBgn0005783, FBgn0015613" protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement calmodulin binding ; GO:0005516 | traceable author statement calmodulin-dependent protein phosphatase activity ; GO:0033192 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with sra calcium-dependent protein serine/threonine phosphatase activity ; GO:0004723 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9XZL8 sleep ; GO:0030431 | inferred from direct assay regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from genetic interaction with sra protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity protein dephosphorylation ; GO:0006470 | non-traceable author statement female meiotic division ; GO:0007143 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype calcineurin complex ; GO:0005955 | inferred from sequence or structural similarity "DmPp2B-14D, canA, PP2B 14D, CG9842, Pp12-14D, CnnA14D, PP2B, D33, PpD33, Pp2B-14DF, CanA14D, Pp2B-14D, PP2B-14D, CnA, Pp2B-14D/CaN, Pp2b-14D, CanA, CaNA" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG9842 11-Aug-17 DroID_v2017_08 "Drer\ppp3ccb, Drer\ppp3cca, Drer\ppp3cb, Drer\ppp3ca" "Scer\CMP2, Scer\CNA1" Cele\tax-6 "Xtro\ppp3cc, Xtro\ppp3ca, Xtro\ppp3cb" "Mmus\Ppp3cc, Mmus\Ppp3cb, Mmus\Ppp3ca" "Hsap\PPP3CB, Hsap\PPP3CA, Hsap\PPP3CC" " embryonic stage , larval stage--adult stage , embryonic stage | stage <6 " " embryonic peripheral nervous system

, central nervous system

, organism

" "partially lethal - majority die,germline clone,visible,size defective,lethal,female sterile,meiotic cell cycle defective,sleep defective,locomotor behavior defective,viable" "eye,ommatidium,wing vein,wing,posterior compartment,wing blade,eye photoreceptor cell,photoreceptor cell R7,photoreceptor cell R3,photoreceptor cell R4,interommatidial bristle,egg & nuclear chromosomenos.UTR.THsimVP16,egg & spindlenos.UTR.THsimVP16,oocyte & nuclear chromatinnos.UTR.THsimVP16,oocyte & nucleusnos.UTR.THsimVP16" DRSC20270 EK -0.657160719 -0.936395856 2.226963277 1.767199934 -1.635530198 0.640051797 FBgn0038180 Cht5 Chitinase 5 http://flybase.org/reports/FBgn0038180 protein_coding_gene chitinase activity ; GO:0004568 | inferred from direct assay chitin binding ; GO:0008061 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 wound healing ; GO:0042060 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype chitin catabolic process ; GO:0006032 | inferred from direct assay" extracellular space ; GO:0005615 | inferred from direct assay "CG9307, Cht5, DmCHT5, DmCht5" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR002557:Chitin binding domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG9307 11-Aug-17 DroID_v2017_08 "Drer\ovgp1, Drer\si:ch211-226m16.2, Drer\chia.5, Drer\chia.2, Drer\chia.1, Drer\srl" Scer\CTS2 "Cele\cht-4, Cele\cht-1, Cele\cht-3, Cele\cht-2" "Xtro\chit1, Xtro\chia, Xtro\ctbs, Xtro\srl, Xtro\LOC548945" "Mmus\Ovgp1, Mmus\Chil6, Mmus\Chia1, Mmus\Chit1, Mmus\Chil3, Mmus\Chil4, Mmus\Ctbs, Mmus\Chil1, Mmus\Srl, Mmus\Chil5" "Hsap\CHIT1, Hsap\CHIA, Hsap\SRL, Hsap\CHI3L1, Hsap\CHI3L2, Hsap\OVGP1" "viable,fertile" FBgn0043047 anon-60Af anon-60Af http://flybase.org/reports/FBgn0043047 gene - - - anon-60Af - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038845 CG10827 - http://flybase.org/reports/FBgn0038845 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG10827 "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG10827 11-Aug-17 DroID_v2017_08 "Drer\alpl, Drer\alp3, Drer\alpi.1, Drer\alpi.2" Scer\PHO8 - "Xtro\alpi.1, Xtro\alpl" "Mmus\Alppl2, Mmus\Alpi, Mmus\Akp3, Mmus\Alpl" "Hsap\ALPL, Hsap\ALPI, Hsap\ALPP, Hsap\ALPPL2" viable DRSC14269 K 0.578620853 -0.366896562 0.056720263 -0.118483537 1.949854475 0.036920914 FBgn0015357 anon-9Ba anon-9Ba http://flybase.org/reports/FBgn0015357 - gene - - - anon-9Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069937 CG41107 - http://flybase.org/reports/FBgn0069937 protein_coding_gene - - - CG41107 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035158 CG13895 - http://flybase.org/reports/FBgn0035158 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" - - CG13895 "IPR007889:DNA binding HTH domain, Psq-type, IPR006600:HTH CenpB-type DNA-binding domain, IPR009057:Homeobox domain-like" CG13895 11-Aug-17 DroID_v2017_08 - - Cele\unc-98 - - - viable FBgn0052651 CG32651 - http://flybase.org/reports/FBgn0052651 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32651 IPR031732:Protein of unknown function DUF4729 CG32651 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030183 CG15309 - http://flybase.org/reports/FBgn0030183 protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "BcDNA:GH10478, CG15309" "IPR004910:Yippee/Mis18/Cereblon, IPR034751:Yippee domain" CG15309 11-Aug-17 DroID_v2017_08 "Drer\ypel5, Drer\ypel2a, Drer\ypel1, Drer\ypel2b, Drer\ypel3" Scer\MOH1 "Cele\B0546.3, Cele\B0546.4, Cele\F37A8.5" "Xtro\ypel5, Xtro\ypel1, Xtro\ypel2" "Mmus\Ypel1, Mmus\Ypel2, Mmus\Ypel3, Mmus\Ypel5, Mmus\Ypel4" "Hsap\YPEL3, Hsap\YPEL1, Hsap\YPEL5, Hsap\YPEL4, Hsap\YPEL2" viable FBgn0069931 CG41120 - http://flybase.org/reports/FBgn0069931 protein_coding_gene - - - CG41120 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031996 CG8460 - http://flybase.org/reports/FBgn0031996 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781" endomembrane system ; GO:0012505 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence or structural similarity with UniProtKB:Q9BWS9 CG8460 "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily" CG8460 11-Aug-17 DroID_v2017_08 Drer\chid1 - "Cele\chil-10, Cele\chil-14" Xtro\chid1 Mmus\Chid1 Hsap\CHID1 FBgn0016851 l(1)N32 lethal (1) N32 http://flybase.org/reports/FBgn0016851 - gene - - - "l(1)N32, N32" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014267 l(2)k08225 lethal (2) k08225 http://flybase.org/reports/FBgn0014267 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc growth ; GO:0007446 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)82/25, l(2)k08225" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval brain,brain" FBgn0028888 CG4168 - http://flybase.org/reports/FBgn0028888 protein_coding_gene - - - "CG4168, BG:DS03192.2" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG4168 11-Aug-17 DroID_v2017_08 "Drer\lrrc23, Drer\si:dkey-182i3.11, Drer\igfals" "Scer\ILV5, Scer\CYR1, Scer\VID22" "Cele\lron-14, Cele\lron-15, Cele\F08G2.5, Cele\lron-11" - "Mmus\Id3, Mmus\Lrrc23, Mmus\Nepn, Mmus\Igfals" "Hsap\LRRC23, Hsap\IGFALS" FBgn0067638 wey weyprecht http://flybase.org/reports/FBgn0067638 gene - bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype - wey - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "follicle cell,germline clone" FBgn0010185 tu(3)1b tu(3)1b http://flybase.org/reports/FBgn0010185 - gene - - - tu(3)1b - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,partially lethal - majority die,some die during larval stage" FBgn0020267 n-judah n-judah http://flybase.org/reports/FBgn0020267 - gene - - - n-judah - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002140 l(2)K305 lethal (2) K305 http://flybase.org/reports/FBgn0002140 - gene - - - l(2)K305 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263619 CR43628 - http://flybase.org/reports/FBgn0263619 non_protein_coding_gene - - - CR43628 - CR43628 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063924 Kaz1-ORFA Kaz1-ORFA http://flybase.org/reports/FBgn0063924 pseudogene_attribute - - - "ORF A, CG33045, Kaz1, CG33790, Kaz1-ORFA, Kaz1-ORF A, CR33790" IPR002350:Kazal domain CR33790 11-Aug-17 DroID_v2017_08 - - - - - - DRSC08669 K 0.326169449 0.057840784 0.010269493 0.222864967 -1.951156028 -0.47099077 FBgn0053639 CG33639 - http://flybase.org/reports/FBgn0053639 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model" "CG5936, CG16958, anon-WO0170980.41, anon-WO0170980.40, CG33639" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG33639 11-Aug-17 DroID_v2017_08 Drer\gpr142 - "Cele\Y70D2A.1, Cele\AH9.1, Cele\C17H11.1, Cele\B0563.6" - "Mmus\Adra1a, Mmus\Gpr142, Mmus\Gpr139" "Hsap\GPR142, Hsap\GPR139" viable DRSC22820 EK 0.587255647 1.492565 -2.488665965 0.112975947 0.756068648 1.91784939 FBgn0000863 fs(1)M57 female sterile (1) M57 http://flybase.org/reports/FBgn0000863 - gene - - - fs(1)M57 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" "egg,maternal effect,chorion | maternal effect" FBgn0264468 CR43876 - http://flybase.org/reports/FBgn0264468 non_protein_coding_gene - - - CR43876 - CR43876 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038889 Fancm Fanconi anemia group M helicase http://flybase.org/reports/FBgn0038889 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006935 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006935 3'-5' DNA helicase activity ; GO:0043138 | inferred from sequence or structural similarity with SGD:S000001441 helicase activity ; GO:0004386 | inferred from sequence or structural similarity reciprocal DNA recombination ; GO:0035825 | inferred from mutant phenotype double-strand break repair via synthesis-dependent strand annealing ; GO:0045003 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype recombinational repair ; GO:0000725 | inferred from sequence or structural similarity with SGD:S000001441 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000001441 "cg7922, Fancm, CG7922" "IPR001650:Helicase, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR006935:Helicase/UvrB, N-terminal" CG7922 11-Aug-17 DroID_v2017_08 "Drer\dhx58, Drer\ifih1, Drer\dicer1, Drer\fancm" "Scer\MPH1, Scer\IRC3" "Cele\dcr-1, Cele\drh-1, Cele\drh-3" "Xtro\ddx58, Xtro\ifih1, Xtro\dhx58, Xtro\fancm, Xtro\dicer1" "Mmus\Dhx58, Mmus\Ddx58, Mmus\Fancm, Mmus\Ifih1, Mmus\Dicer1" "Hsap\DICER1, Hsap\IFIH1, Hsap\DHX58, Hsap\DDX58, Hsap\FANCM" FBgn0261358 CG42635 - http://flybase.org/reports/FBgn0261358 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42635, CG15149" - CG42635 11-Aug-17 DroID_v2017_08 - - Cele\ska-3 - - - viable FBgn0065816 l(2)SH0378 lethal (2) SH0378 http://flybase.org/reports/FBgn0065816 gene - - - "l(2)SH0378, l(2)SH2 0378" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025742 mtm myotubularin http://flybase.org/reports/FBgn0025742 - protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity with protein_id:AAC51682.1 inferred from sequence or structural similarity with protein_id:CAA89640.1 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement phosphatidylinositol-3-phosphatase activity ; GO:0004438 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Sbf dephosphorylation ; GO:0016311 | inferred from electronic annotation with InterPro:IPR016130 protein dephosphorylation ; GO:0006470 | non-traceable author statement response to wounding ; GO:0009611 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "MTM1, CG9115, dMTMH1, mtm" "IPR004182:GRAM domain, IPR010569:Myotubularin-like phosphatase domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR030564:Myotubularin family, IPR011993:PH domain-like, IPR029021:Protein-tyrosine phosphatase-like, IPR003595:Protein-tyrosine phosphatase, catalytic" CG9115 11-Aug-17 DroID_v2017_08 "Drer\mtmr7b, Drer\zgc:154055, Drer\mtmr10, Drer\mtmr9, Drer\mtmr2, Drer\mtmr8, Drer\mtmr12, Drer\mtmr6, Drer\mtmr7a, Drer\mtmr1b, Drer\mtm1, Drer\mtmr1a" Scer\YMR1 "Cele\mtm-6, Cele\mtm-1" "Xtro\mtmr12, Xtro\LOC100216114, Xtro\asb12.2, Xtro\mtmr6, Xtro\mtmr1, Xtro\mtmr7, Xtro\mtmr9, Xtro\mtmr2, Xtro\mtmr10, Xtro\mtm1" "Mmus\Mtmr1, Mmus\Mtmr11, Mmus\Mtmr6, Mmus\Mtm1, Mmus\Mtmr9, Mmus\Mtmr7, Mmus\Mtmr12, Mmus\Mtmr10, Mmus\Mtmr2" "Hsap\MTMR6, Hsap\MTMR2, Hsap\MTMR11, Hsap\MTMR1, Hsap\MTMR7, Hsap\MTMR8, Hsap\MTMR10, Hsap\MTMR12, Hsap\MTMR9, Hsap\MTM1" "lethal - all die before end of larval stage,some die during third instar larval stage,wound healing defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,majority die during pupal stage,developmental rate defective,flightless,viable" "embryonic/larval hemocyte,sessile hemocyte,abdominal temporary eclosion muscle DA,temporary eclosion muscle,testis sheath muscle,T-tubuleMef2.PR,macrophage" FBgn0259703 CG42357 - http://flybase.org/reports/FBgn0259703 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32308, CG42357" - CG42357 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262996 CR43304 - http://flybase.org/reports/FBgn0262996 non_protein_coding_gene - - - CR43304 - CR43304 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019773 l(1)38 lethal (1) 38 http://flybase.org/reports/FBgn0019773 - gene - - - l(1)38 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033257 sand sandman http://flybase.org/reports/FBgn0033257 protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "cellular response to dopamine ; GO:1903351 | inferred from mutant phenotype potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6 negative regulation of membrane potential ; GO:0045837 | inferred from mutant phenotype negative regulation of circadian sleep/wake cycle, sleep ; GO:0042321 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" "anon-WO0109301.46, anon-WO0109301.45, anon-WO0109301.44, anon-WO0109301.43, anon-WO0109301.42, anon-WO0109301.41, anon-WO0109301.40, anon-WO0109301.39, anon-WO0109301.5, CG8713, sand" "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG8713 11-Aug-17 DroID_v2017_08 "Drer\kcnk5a, Drer\kcnk10a, Drer\kcnk7, Drer\kcnk18, Drer\kcnk5b, Drer\kcnk6, Drer\kcnk10b, Drer\kcnk1a, Drer\kcnk1b, Drer\kcnk2a" Scer\TOK1 "Cele\twk-13, Cele\twk-28, Cele\twk-48, Cele\twk-39" "Xtro\kcnk1, Xtro\kcnk2, Xtro\kcnk10, Xtro\kcnk5, Xtro\kcnk4, Xtro\LOC100486031, Xtro\kcnk7, Xtro\kcnk18, Xtro\kcnk16, Xtro\kcnk6" "Mmus\Kcnk7, Mmus\Kcnk6, Mmus\Kcnk5, Mmus\Kcnk18, Mmus\Kcnk16, Mmus\Kcnk10, Mmus\Kcnk1, Mmus\Kcnk4, Mmus\Kcnk2" "Hsap\KCNK1, Hsap\KCNK10, Hsap\KCNK6, Hsap\KCNK7, Hsap\KCNK16, Hsap\KCNK17, Hsap\KCNK5, Hsap\KCNK2, Hsap\KCNK4, Hsap\KCNK18" "viable,fertile" FBgn0083054 snoRNA:Psi18S-1347a snoRNA:Psi18S-1347a http://flybase.org/reports/FBgn0083054 snoRNA_gene - - - "snoRNA:Psi18S-1347a, Psi18S-1347a, psi18S-1347a, Psi 18S-1347a(SnoR203), CR34544" - CR34544 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267098 CR45538 - http://flybase.org/reports/FBgn0267098 non_protein_coding_gene - - - CR45538 - CR45538 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032588 CG5968 - http://flybase.org/reports/FBgn0032588 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT27976, CG5968" IPR031957:Domain of unknown function DUF4777 CG5968 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003491 sps spastic http://flybase.org/reports/FBgn0003491 - gene - - - sps - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,sterile,uncoordinated,behavior defective" FBgn0041782 S(Sev-CycE)D30 S(Sev-CycE)D30 http://flybase.org/reports/FBgn0041782 gene - - - S(Sev-CycE)D30 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035679 CG10467 - http://flybase.org/reports/FBgn0035679 protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718 aldose 1-epimerase activity ; GO:0004034 | inferred from biological aspect of ancestor with PANTHER:PTN000009552" glucose metabolic process ; GO:0006006 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 galactose catabolic process via UDP-galactose ; GO:0033499 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 extracellular region ; GO:0005576 | inferred from direct assay CG10467 "IPR008183:Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013:Galactose mutarotase-like domain, IPR018052:Aldose 1-epimerase, conserved site, IPR014718:Glycoside hydrolase-type carbohydrate-binding, IPR015443:Aldose 1-epimerase" CG10467 11-Aug-17 DroID_v2017_08 Drer\galm "Scer\YHR210C, Scer\GAL10, Scer\YNR071C" "Cele\Y19D10A.16, Cele\C01B4.6" Xtro\galm Mmus\Galm Hsap\GALM viable DRSC09728 K 0.066956422 0.007044745 -0.526193059 0.660274526 -0.613578298 2.165825822 FBgn0001750 l(1)HM22 lethal (1) HM22 http://flybase.org/reports/FBgn0001750 - gene - - - l(1)HM22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0001370 l(1)2Ac lethal (1) 2Ac http://flybase.org/reports/FBgn0001370 FBgn0001368 gene - - - "l(1)2Aa, l(1)2Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0085661 CG41511 - http://flybase.org/reports/FBgn0085661 protein_coding_gene - - - CG41511 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042691 Su(Ste)OR Suppressor of Stellate orphon http://flybase.org/reports/FBgn0042691 pseudogene_attribute - - - "SuSteOR, Su(Ste)OR" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004107 Cdk2 Cyclin-dependent kinase 2 http://flybase.org/reports/FBgn0004107 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity with SGD:S000000364 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" regulation of meiotic cell cycle ; GO:0051445 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000000364 protein phosphorylation ; GO:0006468 | non-traceable author statement mitotic cell cycle phase transition ; GO:0044772 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 regulation of mitotic cell cycle ; GO:0007346 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from sequence or structural similarity with SGD:S000000364 microtubule cytoskeleton organization ; GO:0000226 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 JAK-STAT cascade ; GO:0007259 | inferred from physical interaction with Stat92E G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from sequence or structural similarity with SGD:S000000364 histone phosphorylation ; GO:0016572 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 mitotic spindle ; GO:0072686 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 microtubule associated complex ; GO:0005875 | inferred from direct assay "cdc2c, Cdk2, cdk2, CDK2, Cdc2c, CG10498, CDK2/CDC2c, S(Sev-CycE)3A, DmCdk2, Dmcdc2c, Dcdc2c, CDC2c, dCdk2, CDC2C, DmCdc2c" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG10498 11-Aug-17 DroID_v2017_08 "Drer\LOC100536316, Drer\cdk21, Drer\cdk5, Drer\cdk17, Drer\cdk15, Drer\cdk6, Drer\cdk1, Drer\cdk14, Drer\cdk2, Drer\si:dkey-166c18.1, Drer\cdk4, Drer\cdk16" "Scer\PHO85, Scer\CDC28, Scer\CAK1, Scer\CTK1" "Cele\ZC123.4, Cele\cdk-5, Cele\cdk-1, Cele\cdk-2" "Xtro\cdk18, Xtro\cdk2, Xtro\cdk1, Xtro\cdk17, Xtro\cdk15, Xtro\cdk6, Xtro\cdk16, Xtro\cdk14, Xtro\cdk4, Xtro\cdk5" "Mmus\Cdk2, Mmus\Cdk18, Mmus\Cdk5, Mmus\Cdk17, Mmus\Cdk14, Mmus\Cdk15, Mmus\Cdk6, Mmus\Cdk16, Mmus\Cdk4, Mmus\E030030I06Rik, Mmus\Cdk1" "Hsap\CDK18, Hsap\CDK15, Hsap\CDK1, Hsap\CDK5, Hsap\CDK17, Hsap\CDK3, Hsap\CDK4, Hsap\CDK6, Hsap\CDK14, Hsap\CDK16, Hsap\CDK2" " embryonic stage | early , embryonic stage " embryonic central nervous system

"small body,lethal,recessive,wild-type" larval outer optic anlage DRSC16921 IEK -1.417489246 -1.755788586 -2.638859898 -3.688672595 4.262878723 4.709982217 FBgn0035268 CG8001 - http://flybase.org/reports/FBgn0035268 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:24891 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24891 CG8001 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG8001 11-Aug-17 DroID_v2017_08 "Drer\dcaf6, Drer\dcaf8, Drer\wdtc1" Scer\COP1 "Cele\npp-23, Cele\R11D1.1, Cele\adpr-1" "Xtro\dcaf6, Xtro\dcaf8" "Mmus\Dcaf8, Mmus\Wdtc1, Mmus\Dcaf6, Mmus\Pet2" "Hsap\DCAF6, Hsap\DCAF8L1, Hsap\WDTC1, Hsap\DCAF8L2, Hsap\DCAF8" viable FBgn0030340 CG15740 - http://flybase.org/reports/FBgn0030340 protein_coding_gene - - - "i175, CG15740" IPR015943:WD40/YVTN repeat-like-containing domain CG15740 11-Aug-17 DroID_v2017_08 - - - "Xtro\uspl1, Xtro\LOC100494818" - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC23079 K 3.84774172 -0.800226233 FBgn0050389 CG30389 - http://flybase.org/reports/FBgn0050389 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR019130 "CG4126, CG10518, BcDNA:AT02070, CG30389" "IPR019130:Macoilin, IPR015943:WD40/YVTN repeat-like-containing domain" CG30389 11-Aug-17 DroID_v2017_08 "Drer\tmem57b, Drer\si:dkey-12h9.6, Drer\tmem57a" - Cele\maco-1 Xtro\tmem57 Mmus\Tmem57 Hsap\TMEM57 "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0000282 cel celibate http://flybase.org/reports/FBgn0000282 - gene - copulation ; GO:0007620 | non-traceable author statement male courtship behavior ; GO:0008049 | traceable author statement - cel - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,mating defective,male" FBgn0032717 CG10600 - http://flybase.org/reports/FBgn0032717 protein_coding_gene - - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026306 CG10600 IPR026306:Round spermatid basic protein 1 CG10600 11-Aug-17 DroID_v2017_08 Drer\LOC100330644 - Cele\dpy-21 "Xtro\rsbn1, Xtro\rsbn1l" "Mmus\Rsbn1, Mmus\Rsbn1l" "Hsap\RSBN1L, Hsap\RSBN1" "viable,fertile" FBgn0052532 CG32532 - http://flybase.org/reports/FBgn0052532 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG14203, CG14202, CG14201, CG32532" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain" CG32532 11-Aug-17 DroID_v2017_08 "Drer\hoxa2b, Drer\hoxc9a, Drer\hoxb1a, Drer\hoxa9b, Drer\hoxa9a, Drer\hoxb6b, Drer\arxa, Drer\msx1b, Drer\prop1, Drer\hoxd9a, Drer\hoxb1b, Drer\hoxb9a, Drer\hesx1" Scer\PHO2 "Cele\unc-42, Cele\pax-3, Cele\mls-2" "Xtro\hoxb9, Xtro\hoxa1, Xtro\tlx1, Xtro\hoxd9, Xtro\hoxa5, Xtro\hoxa3, Xtro\hesx1" "Mmus\Cdx4, Mmus\Hoxb1, Mmus\Dlx3, Mmus\Hoxb3, Mmus\Hoxc9, Mmus\Hoxd9, Mmus\Hoxa9, Mmus\Barx2, Mmus\Prop1, Mmus\Hoxb9, Mmus\Tlx2, Mmus\Nanog, Mmus\Hesx1" "Hsap\HOXD9, Hsap\HOXB3, Hsap\HOXB9, Hsap\CDX4, Hsap\NKX2-8, Hsap\HOXA3, Hsap\HESX1, Hsap\PAX4, Hsap\HOXA5, Hsap\DLX4, Hsap\HOXA9, Hsap\HOXC9, Hsap\BARX2, Hsap\PROP1, Hsap\HOXB1, Hsap\HOXA1, Hsap\MSX1" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC19556 K 0.405889417 0.556868105 -0.462647501 0.559554584 -0.317812098 -1.51757777 FBgn0263565 mir-4950 mir-4950 stem loop http://flybase.org/reports/FBgn0263565 miRNA_gene - - - "mir-4950, dme-mir-4950, CR43550" - CR43550 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028402 Sin Sex-lethal interactor http://flybase.org/reports/FBgn0028402 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sxl RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000249148 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR006886" DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000249148 "sin, CG10582, Sin" IPR006886:DNA-directed RNA polymerase III subunit Rpc5 CG10582 11-Aug-17 DroID_v2017_08 Drer\polr3e Scer\RPC37 Cele\W06E11.1 Xtro\polr3e Mmus\Polr3e "Hsap\LOC101060521, Hsap\POLR3E" " embryonic stage , embryonic stage | early "

ubiquitous lethal DRSC11880 E -0.669581338 0.830418859 -2.141370535 -0.50721451 -0.784533209 -0.254867776 FBgn0039196 CG17781 - http://flybase.org/reports/FBgn0039196 protein_coding_gene - - - CG17781 IPR006631:Protein of unknown function DM4/12 CG17781 11-Aug-17 DroID_v2017_08 - - - - - - DRSC15266 K 0.33721108 -0.132658862 -0.140628841 0.289813216 0.079074587 2.121301381 FBgn0036454 CG17839 - http://flybase.org/reports/FBgn0036454 protein_coding_gene - - nucleus ; GO:0005634 | inferred from direct assay "CT39634, CG17839, 17839" "IPR002602:Domain of unknown function DB, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013151:Immunoglobulin, IPR003598:Immunoglobulin subtype 2" CG17839 11-Aug-17 DroID_v2017_08 - Scer\OPY2 "Cele\igdb-2, Cele\wrk-1, Cele\igdb-3, Cele\igdb-1" - - - "viable,fertile" FBgn0033807 AQP aquaporin http://flybase.org/reports/FBgn0033807 protein_coding_gene - - cellular_component ; GO:0005575 | no biological data available "AQP-dr, CG12251, AQP, Aqp 12L" "IPR016697:Aquaporin 11/12, IPR023271:Aquaporin-like, IPR031145:Invertebrate aquaporin-10" CG12251 11-Aug-17 DroID_v2017_08 "Drer\aqp11, Drer\aqp12" - "Cele\aqp-10, Cele\aqp-9, Cele\aqp-11" - "Mmus\Aqp12, Mmus\Aqp11" "Hsap\AQP11, Hsap\AQP12B, Hsap\AQP12A" FBgn0261729 EC1608 - http://flybase.org/reports/FBgn0261729 gene - - - EC1608 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0030654 CG15643 - http://flybase.org/reports/FBgn0030654 protein_coding_gene - - - "CG32583, CG15643" IPR019352:Uncharacterised protein family UPF0454 CG15643 11-Aug-17 DroID_v2017_08 Drer\zgc:110063 - - Xtro\c12orf49 Mmus\2410131K14Rik Hsap\C12orf49 FBgn0038127 CG8476 - http://flybase.org/reports/FBgn0038127 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8476 IPR001623:DnaJ domain CG8476 11-Aug-17 DroID_v2017_08 "Drer\dnajc16, Drer\dnaja3b, Drer\dnajc4, Drer\dnajc24, Drer\dnaja3a, Drer\dnajc16l" Scer\MDJ1 "Cele\dnj-3, Cele\dnj-4" "Xtro\dnajc16, Xtro\dnajc24, Xtro\dnajc4" "Mmus\Dnajc24, Mmus\Dnaja3, Mmus\Dnajc4, Mmus\Dnajc16" "Hsap\DNAJC24, Hsap\DNAJA3, Hsap\DNAJC16, Hsap\DNAJC4" FBgn0014403 vcg ventral central gaps http://flybase.org/reports/FBgn0014403 - gene - - - vcg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "longitudinal connective,commissure,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt" FBgn0051687 CG31687 - http://flybase.org/reports/FBgn0051687 protein_coding_gene - regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from electronic annotation with InterPro:IPR007192 regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype anaphase-promoting complex ; GO:0005680 | inferred from electronic annotation with InterPro:IPR007192 "CG31687, CG31687-PA" "IPR007192:Cdc23, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR011990:Tetratricopeptide-like helical domain" CG31687 11-Aug-17 DroID_v2017_08 Drer\cdc23 Scer\CDC23 Cele\mat-3 Xtro\cdc23 Mmus\Cdc23 Hsap\CDC23 planar polarity defective "ommatidium,wing hair,supernumerary" FBgn0053512 dpr4 defective proboscis extension response 4 http://flybase.org/reports/FBgn0053512 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 cellular_component ; GO:0005575 | no biological data available "CG12593, Dpr-4, CT34497, CG14707, CG33512, dpr4, Dpr4" "IPR013106:Immunoglobulin V-set domain, IPR003598:Immunoglobulin subtype 2, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype" CG33512 11-Aug-17 DroID_v2017_08 "Drer\LOC108191960, Drer\LOC100333196, Drer\zgc:112965, Drer\LOC101885444, Drer\si:dkey-65b12.12, Drer\LOC101885725, Drer\si:ch211-163c2.2" - Cele\zig-8 "Xtro\obsl1, Xtro\nfasc" "Mmus\Amica1, Mmus\Gm1123" Hsap\JAML viable FBgn0001238 hv heavy vein http://flybase.org/reports/FBgn0001238 - gene - - - hv - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,crossvein,wing,eye,posterior scutellar bristle" FBgn0065777 l(2)SH0449 lethal (2) SH0449 http://flybase.org/reports/FBgn0065777 gene - - - "l(2)SH0449, l(2)SH2 0449" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0017558 Pdk Pyruvate dehydrogenase kinase http://flybase.org/reports/FBgn0017558 FBgn0062465 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with UniProtKB:Q15118 pyruvate dehydrogenase (acetyl-transferring) kinase activity ; GO:0004740 | inferred from sequence or structural similarity with UniProtKB:Q15118 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:Q15118 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q15118 "CG8808, DmPdk, DmPDK, BcDNA:LD09837, Pdk, pdk, PDK" "IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR005467:Histidine kinase domain, IPR018955:Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal" CG8808 11-Aug-17 DroID_v2017_08 "Drer\pdk4, Drer\bckdk, Drer\pdk2a, Drer\pdk1, Drer\pdk3a, Drer\pdk2b, Drer\pdk3b" "Scer\PKP1, Scer\PKP2" Cele\pdhk-2 "Xtro\pdk4, Xtro\pdk1, Xtro\bckdk, Xtro\pdk3" "Mmus\Bckdk, Mmus\Pdk4, Mmus\Pdk1, Mmus\Pdk3, Mmus\Pdk2" "Hsap\PDK4, Hsap\PDK2, Hsap\BCKDK, Hsap\PDK3, Hsap\PDK1" " adult stage | female , embryonic stage | 0-20 hr , pupal stage , adult stage | male , larval stage | third instar , embryonic stage "

ubiquitous "viable,fertile" FBgn0065721 l(2)SH0569 lethal (2) SH0569 http://flybase.org/reports/FBgn0065721 gene - - - "l(2)SH0569, l(2)SH2 0569" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005448 l(1)v223 lethal (1) v223 http://flybase.org/reports/FBgn0005448 - gene - - - "l(1)223, l(1)v223" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039131 CG12268 - http://flybase.org/reports/FBgn0039131 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - CG12268 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG12268 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR1, Hsap\FAR2" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263771 CR43688 - http://flybase.org/reports/FBgn0263771 pseudogene_attribute - - - CR43688 - CR43688 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083167 Neb-cGP Neb-cGP http://flybase.org/reports/FBgn0083167 protein_coding_gene hormone activity ; GO:0005179 | traceable author statement regulation of growth ; GO:0040008 | traceable author statement extracellular space ; GO:0005615 | traceable author statement mitochondrial proton-transporting ATP synthase complex ; GO:0005753 | inferred from biological aspect of ancestor with PANTHER:PTN002145699 "pncr006:X, CG15304, BcDNA:RH45340, BcDNA:RE31692, Neb-cGP" IPR009125:DAPIT CG15304 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-80c12.10 - - - Mmus\Usmg5 Hsap\USMG5 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0000056 Adhr Adh-related http://flybase.org/reports/FBgn0000056 "FBgn0052954, FBtr0080648, FBpp0080216, FBtr0080649, FBpp0080217, FBtr0080650, FBpp0080218, FBtr0080651, FBpp0080219, FBtr0080652, FBpp0080220, FBtr0080653, FBpp0080221, FBtr0080654, FBpp0080222, FBtr0080655, FBpp0080223" protein_coding_gene alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from electronic annotation with InterPro:IPR002424 NAD binding ; GO:0051287 | NOT traceable author statement alcohol dehydrogenase (NAD) activity ; GO:0004022 | NOT traceable author statement oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002424 cellular_component ; GO:0005575 | no biological data available "Adh-dup, ADHR, BG:DS01486.9, ADH[r], Adh[r], 3'ORF, CG32954, CG3484, Adhr" "IPR002424:Alcohol dehydrogenase, insect-type, IPR002427:Alcohol dehydrogenase-related, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site, IPR002347:Short-chain dehydrogenase/reductase SDR" CG3484 11-Aug-17 DroID_v2017_08 "Drer\hsd17b2, Drer\zgc:56585, Drer\hsd11b2, Drer\hpgd" Scer\SPS19 "Cele\T01G6.10, Cele\C01G12.5, Cele\dhs-16, Cele\W03F9.9, Cele\T01G6.1, Cele\dhs-2, Cele\drd-5, Cele\dhs-20, Cele\C06B8.3" Xtro\hpgd "Mmus\Hsd17b2, Mmus\Hpgd, Mmus\Hsd11b2, Mmus\Bdh1" "Hsap\HSD11B2, Hsap\HPGD, Hsap\HSD17B2, Hsap\BDH1" FBgn0041180 Tep4 Thioester-containing protein 4 http://flybase.org/reports/FBgn0041180 protein_coding_gene "endopeptidase inhibitor activity ; GO:0004866 | inferred from electronic annotation with InterPro:IPR001599, InterPro:IPR002890" multicellular organism reproduction ; GO:0032504 | inferred from expression pattern response to fungus ; GO:0009620 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR011626 extracellular space ; GO:0005615 | inferred from sequence model "Tep4, TepIV, CG10363, CT29102, dTEPIV, TEP IV, TEP4mel, tep4, TEP4, tepIV, TEPIV, Tep IV" "IPR002890:Alpha-2-macroglobulin, N-terminal, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR009048:Alpha-macroglobulin, receptor-binding, IPR011625:Alpha-2-macroglobulin, N-terminal 2, IPR011626:Alpha-macroglobulin complement component, IPR014756:Immunoglobulin E-set, IPR019742:Alpha-2-macroglobulin, conserved site, IPR013783:Immunoglobulin-like fold, IPR019565:Alpha-2-macroglobulin, thiol-ester bond-forming, IPR001599:Alpha-2-macroglobulin" CG10363 11-Aug-17 DroID_v2017_08 "Drer\a2ml, Drer\cd109, Drer\si:dkey-46g23.2, Drer\c3b.2, Drer\c3b.1, Drer\cpamd8, Drer\si:dkey-8k3.2, Drer\c3a.6, Drer\c3a.2, Drer\zgc:165518, Drer\c3a.4, Drer\c5, Drer\si:dkey-52d15.2, Drer\c4, Drer\c3a.3, Drer\c3a.1" - Cele\tep-1 "Xtro\a2m, Xtro\c5, Xtro\c3, Xtro\c4a, Xtro\pzp, Xtro\a2ml1" "Mmus\Hc, Mmus\Mug1, Mmus\C3, Mmus\C4b, Mmus\Mug2, Mmus\Cd109" "Hsap\CD109, Hsap\C4B_2, Hsap\C4B, Hsap\C5, Hsap\CPAMD8, Hsap\C4A, Hsap\C3, Hsap\PZP, Hsap\A2ML1" viable FBgn0058114 CG40114 - http://flybase.org/reports/FBgn0058114 protein_coding_gene - - - CG40114 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032620 CG12288 - http://flybase.org/reports/FBgn0032620 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - microtubule associated complex ; GO:0005875 | inferred from direct assay "cg12288, CG12288" "IPR000504:RNA recognition motif domain, IPR034220:RBM34, RNA recognition motif 1" CG12288 11-Aug-17 DroID_v2017_08 "Drer\hnrnpaba, Drer\srsf10a, Drer\hnrnpd, Drer\trnau1apa, Drer\rbm34, Drer\trnau1apb, Drer\raly, Drer\zcrb1, Drer\hnrnpabb, Drer\dazl, Drer\hnrnpa1b, Drer\hnrnpc, Drer\wu:fq32h04, Drer\ncoa5, Drer\eif4h, Drer\eif4ba, Drer\cirbpa, Drer\hnrnpa3, Drer\zgc:55733" "Scer\NAM8, Scer\NGR1, Scer\MUD1, Scer\NOP12, Scer\NOP6, Scer\NAB6, Scer\CWC2, Scer\MRN1" "Cele\F11A10.7, Cele\EEED8.4, Cele\T08B6.5" "Xtro\hnrnpdl, Xtro\trnau1ap, Xtro\hnrnpc, Xtro\ralyl, Xtro\eif4h, Xtro\hnrnpd, Xtro\cirbp, Xtro\hnrnpa2b1, Xtro\raly, Xtro\hnrnpa3, Xtro\hnrnpab, Xtro\hnrnpa1, Xtro\rbm34, Xtro\eif4b, Xtro\dazl" "Mmus\Tra2b, Mmus\Hnrnpc, Mmus\Trnau1ap, Mmus\Rbm34, Mmus\Eif4h, Mmus\Srsf12, Mmus\Hnrnpab, Mmus\Boll, Mmus\Hnrnpa3, Mmus\Eif4b, Mmus\Gm21379, Mmus\Rbm31y, Mmus\Cirbp, Mmus\Hnrnpa2b1, Mmus\Zcrb1, Mmus\Slirp, Mmus\Hnrnpa1, Mmus\Hnrnpd, Mmus\Srsf10, Mmus\Raly, Mmus\Dazl" "Hsap\BOLL, Hsap\SRSF10, Hsap\CIRBP, Hsap\RALYL, Hsap\DAZL, Hsap\HNRNPAB, Hsap\DAZ1, Hsap\RBM34, Hsap\EIF4H, Hsap\HNRNPA2B1, Hsap\HNRNPA3, Hsap\HNRNPCL1, Hsap\HNRNPA1, Hsap\HNRNPD, Hsap\TRNAU1AP, Hsap\SLIRP, Hsap\DAZ2, Hsap\RALY, Hsap\EIF4B, Hsap\HNRNPA1L2, Hsap\DAZ4, Hsap\HNRNPC, Hsap\RBM3, Hsap\DAZ3" FBgn0002831 ms(2)E10 male sterile (2) E10 http://flybase.org/reports/FBgn0002831 - gene - - - "ms2.10, ms(2)2.10, ms(2)E10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0051347 CG31347 - http://flybase.org/reports/FBgn0051347 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31347 - CG31347 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0265343 CR44297 - http://flybase.org/reports/FBgn0265343 non_protein_coding_gene - - - CR44297 - CR44297 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264789 CR44019 - http://flybase.org/reports/FBgn0264789 non_protein_coding_gene - - - CR44019 - CR44019 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263846 CG43707 - http://flybase.org/reports/FBgn0263846 protein_coding_gene - - - "CG43707, CG31772, CG31959, CG10020" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR001478:PDZ domain" CG43707 11-Aug-17 DroID_v2017_08 "Drer\pdzph1, Drer\rhpn2, Drer\ppp1r9a, Drer\cnksr1, Drer\ppp1r9ba, Drer\rhpn1" Scer\BOI1 Cele\nab-1 - "Mmus\Pdzph1, Mmus\Rhpn2, Mmus\Ppp1r9a, Mmus\Ipcef1, Mmus\Plekha5, Mmus\Rhpn1, Mmus\Cnksr1, Mmus\Ppp1r9b" "Hsap\PPP1R9B, Hsap\PLEKHA5, Hsap\PPP1R9A, Hsap\CNKSR1, Hsap\RHPN1, Hsap\RHPN2" DRSC22912 K 0.241260386 0.144499459 -0.050174664 1.316653047 1.547089255 0.20151277 FBgn0035107 mri mrityu http://flybase.org/reports/FBgn0035107 protein_coding_gene glycerol kinase activity ; GO:0004370 | NOT inferred from key residues sensory perception of touch ; GO:0050975 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern lateral inhibition ; GO:0046331 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "CG1216, mri, Mri" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG1216 11-Aug-17 DroID_v2017_08 "Drer\kctd6a, Drer\btbd10b, Drer\kctd4, Drer\kctd20, Drer\btbd10a, Drer\kctd6b" - "Cele\btbd-10, Cele\ZC239.15, Cele\F22E5.8" "Xtro\btbd10, Xtro\kctd6" "Mmus\Btbd10, Mmus\Kctd20, Mmus\Kctd6" "Hsap\BTBD10, Hsap\KCTD11, Hsap\KCTD20, Hsap\KCTD6" "viable,visible,neuroanatomy defective,touch sensitivity defective" "chaeta,supernumerary,mesothoracic tergum,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0019743 l(1)8E lethal (1) 8E http://flybase.org/reports/FBgn0019743 - gene - - - "l(1)8, l(1)8E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265382 CR44323 - http://flybase.org/reports/FBgn0265382 non_protein_coding_gene - - - CR44323 - CR44323 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030572 mRpS25 mitochondrial ribosomal protein S25 http://flybase.org/reports/FBgn0030572 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82663 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AI243774 inferred from sequence or structural similarity with EMBL:AW249185 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82663 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AI243774 inferred from sequence or structural similarity with EMBL:AW249185 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82663 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with EMBL:AI243774 inferred from sequence or structural similarity with EMBL:AW249185 "CG14413, MRP-S25, MrpS25, mRpS25, 25mRps" "IPR007741:Ribosomal protein/NADH dehydrogenase domain, IPR012336:Thioredoxin-like fold" CG14413 11-Aug-17 DroID_v2017_08 Drer\mrps25 Scer\MRP49 Cele\mrps-25 Xtro\mrps25 Mmus\Mrps25 Hsap\MRPS25 "viable,visible" trichogen cell FBgn0022006 l(2)k09221 lethal (2) k09221 http://flybase.net/reports/FBgn0022006.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0011611 l(1)I33e16 lethal (1) I33e16 http://flybase.org/reports/FBgn0011611 FBgn0010206 gene - - - "l(1)33e16, l(1)I33e16" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020359 anon-1H11 anon-1H11 http://flybase.org/reports/FBgn0020359 - gene - - - "1H11, anon-1H11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015543 snoRNA:Me28S-A1322 - http://flybase.org/reports/FBgn0015543 - snoRNA_gene - - - "Dm-797, snoR797, Z1, snoRNA Z1, CR32905, snoRNA:Me28S-A1322, Me28S-A1322(Z1), snoRNA:Z1, SnR61, DmSnR61c, chr2R:7409020..7409115" - CR32905 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041159 dos::Hsap\GAB1 GAB1 http://flybase.org/reports/FBgn0041159 engineered_fusion_gene - - - dos::Hsap\GAB1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013447 fs(2)ry11 fs(2)ry11 http://flybase.org/reports/FBgn0013447 - gene - - - "fs(2)11, fs(2)ry11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0085237 CG34208 - http://flybase.org/reports/FBgn0085237 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34208 - CG34208 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002055 l(2)38Aa lethal (2) 38Aa http://flybase.org/reports/FBgn0002055 - gene - - - "l(2)E124P, l(2)38Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0017407 diva divagari http://flybase.org/reports/FBgn0017407 - gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available diva - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male sterile" "photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina anlage,precursor,larval inner optic anlage,larval outer optic anlage" FBgn0051457 CG31457 - http://flybase.org/reports/FBgn0051457 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG4639, CG31457" "IPR012934:Zinc finger, AD-type" CG31457 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011582 Dop1R1 Dopamine 1-like receptor 1 http://flybase.org/reports/FBgn0011582 - protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity dopamine neurotransmitter receptor activity ; GO:0004952 | inferred from sequence or structural similarity dopamine neurotransmitter receptor activity, coupled via Gs ; GO:0001588 | inferred from direct assay dopamine neurotransmitter receptor activity, coupled via Gs ; GO:0001588 | inferred from mutant phenotype" associative learning ; GO:0008306 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype regulation of presynaptic cytosolic calcium ion concentration ; GO:0099509 | inferred from mutant phenotype thermotaxis ; GO:0043052 | inferred from mutant phenotype dopamine receptor signaling pathway ; GO:0007212 | inferred from sequence or structural similarity response to starvation ; GO:0042594 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype response to odorant ; GO:1990834 | inferred from mutant phenotype learning ; GO:0007612 | inferred from mutant phenotype thermosensory behavior ; GO:0040040 | inferred from mutant phenotype visual learning ; GO:0008542 | inferred from mutant phenotype adenylate cyclase-activating dopamine receptor signaling pathway ; GO:0007191 | inferred from direct assay regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype response to sucrose ; GO:0009744 | inferred from mutant phenotype cellular response to sucrose stimulus ; GO:0071329 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR000929 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from sequence model "DopR, Dumb, Dmdop1, dDA1, DA1, dDA1/DmDOP1, DmDop1, DopR35F, CG9652, dumb, D-Dop1, DopR1, DmDOP1, Dop1R1, DR1, DRD1, dopr" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000929:Dopamine receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG9652 11-Aug-17 DroID_v2017_08 "Drer\drd7, Drer\LOC567498, Drer\drd1a, Drer\hrh4, Drer\drd6b, Drer\drd1b, Drer\hrh3, Drer\LOC563567, Drer\LOC101886918, Drer\LOC100331077" - Cele\dop-1 "Xtro\drd1c, Xtro\drd1, Xtro\drd5, Xtro\adra2b" "Mmus\Hrh4, Mmus\Drd1, Mmus\Drd5, Mmus\Adra1a, Mmus\Hrh3" "Hsap\HRH3, Hsap\ADRA1A, Hsap\DRD5, Hsap\HRH4, Hsap\DRD1" "learning defective,flight defective,lethal,some die during immature adult stage,recessive,partially lethal - majority die,male,courtship behavior defective,memory defective,viable,fertile,hyperactive,chemical conditional,hypoactive,thermotaxis behavior defective" DRSC16652 IE -0.728094939 -2.102660702 -0.146151673 -2.955447966 0.544773039 0.55029531 FBgn0086678 fs(3)H813 - http://flybase.org/reports/FBgn0086678 gene - - - "fs(3)H813, H813" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0039860 CG1792 - http://flybase.org/reports/FBgn0039860 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 DNA binding ; GO:0003677 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 CG1792 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1792 11-Aug-17 DroID_v2017_08 "Drer\bcl6ab, Drer\znf341, Drer\znf408, Drer\si:dkeyp-2e4.7, Drer\znf770, Drer\si:dkey-262g12.7" Scer\AZF1 "Cele\Y37F4.6, Cele\ztf-23, Cele\Y55F3AM.14, Cele\blmp-1, Cele\klf-3, Cele\eor-1, Cele\lin-29, Cele\M03D4.4" - "Mmus\Zfp110, Mmus\Zfp24, Mmus\Mtf1, Mmus\Zfp369, Mmus\Zscan5b, Mmus\Zfp341, Mmus\Zfp810, Mmus\Rbak, Mmus\Zfp445" "Hsap\ZNF281, Hsap\ZNF8, Hsap\ZNF274, Hsap\ZNF221, Hsap\ZNF284, Hsap\ZNF341, Hsap\MTF1, Hsap\ZNF560, Hsap\ZNF784, Hsap\ZNF398" "viable,fertile" FBgn0061474 28SrRNA 28SrRNA http://flybase.org/reports/FBgn0061474 rRNA_gene - - - "28S rRNA, 28S, 28S rDNA, 28s rRNA, 28S RNA, NEST:bs30g02, NEST:bs17g11, NEST:bs15g08, NEST:bs10c09, BEST:HL03427, BEST:HL02977, BEST:HL02093, BEST:LD41653, 28SRNA, 28SrRNA, 28S DNA, Mgn570" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016068 slbo::Rat\C-EBP-delta C-EBP-delta http://flybase.org/reports/FBgn0016068 - engineered_fusion_gene - - - "slbo::Rat\C/EBP-delta, slbo::Rat\C-EBP-delta" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020796 oculi-rugosissimi oculi rugosissimi http://flybase.org/reports/FBgn0020796 - gene - - - "or, oculi-rugosissimi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable" ommatidium FBgn0039130 CG5854 - http://flybase.org/reports/FBgn0039130 protein_coding_gene coenzyme binding ; GO:0050662 | inferred from electronic annotation with InterPro:IPR001509 catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001509 - - "anon-WO0118547.306, CG5854" "IPR001509:NAD-dependent epimerase/dehydratase, IPR016040:NAD(P)-binding domain" CG5854 11-Aug-17 DroID_v2017_08 "Drer\nsdhl, Drer\sdr42e2, Drer\hsd3b7, Drer\hsd3b2, Drer\hsd3b1" Scer\ERG26 Cele\F53B1.4 "Xtro\LOC100494546, Xtro\LOC100490622, Xtro\sdr42e1, Xtro\nsdhl, Xtro\hsd3b7" "Mmus\Hsd3b3, Mmus\Hsd3b5, Mmus\Sdr42e1, Mmus\Gm10681, Mmus\Gm4450, Mmus\Hsd3b1, Mmus\Hsd3b4, Mmus\Hsd3b6, Mmus\Hsd3b7, Mmus\Nsdhl, Mmus\Hsd3b2" "Hsap\NSDHL, Hsap\SDR42E2, Hsap\HSD3B2, Hsap\SDR42E1, Hsap\HSD3B7, Hsap\HSD3B1" viable FBgn0036526 CG13450 - http://flybase.org/reports/FBgn0036526 protein_coding_gene - - - CG13450 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035890 CG13667 - http://flybase.org/reports/FBgn0035890 protein_coding_gene "FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR008254 NADPH-hemoprotein reductase activity ; GO:0003958 | inferred from electronic annotation with InterPro:IPR028879" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR003097, InterPro:IPR017927, InterPro:IPR017938, InterPro:IPR023173 biological_process ; GO:0008150 | no biological data available" - CG13667 "IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR001709:Flavoprotein pyridine nucleotide cytochrome reductase, IPR003097:FAD-binding, type 1, IPR008254:Flavodoxin/nitric oxide synthase, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel, IPR028879:NADPH-dependent diflavin oxidoreductase 1, IPR029039:Flavoprotein-like domain, IPR001094:Flavodoxin-like" CG13667 11-Aug-17 DroID_v2017_08 "Drer\imp4, Drer\ndor1" "Scer\NCP1, Scer\TAH18" "Cele\fre-1, Cele\ZK795.3" "Xtro\imp4, Xtro\ndor1" "Mmus\Imp4, Mmus\Ndor1" "Hsap\NDOR1, Hsap\IMP4" viable FBgn0033177 CG11141 - http://flybase.org/reports/FBgn0033177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11141 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR029772:Tectonin beta-propeller repeat-containing protein 2" CG11141 11-Aug-17 DroID_v2017_08 "Drer\hps5, Drer\tecpr2" - Cele\W09G3.6 "Xtro\hps5, Xtro\tecpr2" "Mmus\Hps5, Mmus\Tecpr2" "Hsap\TECPR2, Hsap\HPS5" "viable,fertile,visible" trichogen cell FBgn0024259 acd(2)5N17 auditory courtship defective 5N17 http://flybase.org/reports/FBgn0024259 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5N17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective" FBgn0013687 mt:ori mitochondrial origin http://flybase.org/reports/FBgn0013687 FBgn0002867 - - - - mt:ori - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039796 CG12069 - http://flybase.org/reports/FBgn0039796 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement cAMP-dependent protein kinase activity ; GO:0004691 | inferred from sequence or structural similarity with HGNC:9380" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:9380 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement cAMP-dependent protein kinase complex ; GO:0005952 | inferred from sequence or structural similarity with HGNC:9380 "CG12069, Pka-like" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG12069 11-Aug-17 DroID_v2017_08 "Drer\prkg1b, Drer\LOC556339, Drer\prkacba, Drer\prkacaa, Drer\prkg2, Drer\prkx, Drer\sgk2b, Drer\prkacbb, Drer\prkacab" "Scer\YPK3, Scer\TPK1, Scer\TPK2, Scer\TPK3" "Cele\kin-1, Cele\F47F2.1" "Xtro\prkg2, Xtro\prkacb, Xtro\prkx, Xtro\prkaca" "Mmus\Prkg2, Mmus\Prkaca, Mmus\Prkacb, Mmus\Prkg1, Mmus\Prkx" "Hsap\PRKACB, Hsap\PRKACA, Hsap\PRKG2, Hsap\PRKG1, Hsap\PRKX, Hsap\PRKACG" "male sterile,viable" FBgn0011669 Mst57Db Male-specific RNA 57Db http://flybase.org/reports/FBgn0011669 FBgn0002859 protein_coding_gene molecular_function ; GO:0003674 | no biological data available post-mating behavior ; GO:0045297 | non-traceable author statement oviposition ; GO:0018991 | non-traceable author statement multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "CG5016, mst-1, mst(2)ag-1, Mst57Db" - CG5016 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0050067 Obp50a Odorant-binding protein 50a http://flybase.org/reports/FBgn0050067 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG30067, anon-AE003814.2, Obp50a, DmelObp50a" IPR006170:Pheromone/general odorant binding protein CG30067 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22152 K -0.432014595 0.335792788 -0.190516925 0.04012612 0.565493814 -2.486145714 FBgn0052723 CR32723 - http://flybase.org/reports/FBgn0052723 non_protein_coding_gene - - - CR32723 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260869 CG42579 - http://flybase.org/reports/FBgn0260869 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42579, HDC19846" - CG42579 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005160 l(2)G151 lethal (2) G151 http://flybase.org/reports/FBgn0005160 - gene - - - l(2)G151 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014369 osho one shot http://flybase.org/reports/FBgn0014369 - gene - - - osho - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035141 Cypl Cyclophilin-like http://flybase.org/reports/FBgn0035141 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG13892, cypl, Cypl, cycl" "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG13892 11-Aug-17 DroID_v2017_08 "Drer\ppil1, Drer\snx14" "Scer\CPR3, Scer\CPR5, Scer\CPR2" "Cele\snx-14, Cele\cyn-12, Cele\ZC250.5" "Xtro\snx14, Xtro\ppil1" Mmus\Ppil1 "Hsap\SNX14, Hsap\PPIL1" "viable,lethal" FBgn0061150 l(2)N113 lethal (2) N113 http://flybase.org/reports/FBgn0061150 gene - - - "N113, l(2)N113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052694 CG32694 - http://flybase.org/reports/FBgn0052694 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay "CG18512, CG12649, CG12634, BcDNA:RE02049, CG32694" - CG32694 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0011117 l(1)Q78 lethal (1) Q78 http://flybase.org/reports/FBgn0011117 FBgn0010210 gene - - - l(1)Q78 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267276 CR45712 - http://flybase.org/reports/FBgn0267276 non_protein_coding_gene - - - CR45712 - CR45712 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038385 Fbxl7 F-box and leucine-rich repeat protein 7 http://flybase.org/reports/FBgn0038385 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model "regulation of protein localization ; GO:0032880 | inferred from mutant phenotype cellular protein catabolic process ; GO:0044257 | inferred from mutant phenotype proximal/distal pattern formation, imaginal disc ; GO:0007449 | inferred from mutant phenotype regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype negative regulation of imaginal disc growth ; GO:0045571 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model" "SCF ubiquitin ligase complex ; GO:0019005 | inferred from physical interaction with Cul1, SkpA SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model cell-cell junction ; GO:0005911 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay" "CG4221, FbxL7, FBXL7, Fbxl7, fbxl7" "IPR001810:F-box domain, IPR006553:Leucine-rich repeat, cysteine-containing subtype, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG4221 11-Aug-17 DroID_v2017_08 "Drer\usp43a, Drer\fbxl2, Drer\fbxl13, Drer\si:dkey-192l18.9, Drer\fbxl7, Drer\fbxl20, Drer\usp31, Drer\usp43b" "Scer\GRR1, Scer\RAD7, Scer\AMN1" Cele\fbxl-1 Xtro\fbxl7 "Mmus\Usp31, Mmus\Fbxl7, Mmus\Fbxl13, Mmus\Usp43, Mmus\Fbxl20, Mmus\Fbxl2" "Hsap\FBXL13, Hsap\USP31, Hsap\FBXL2, Hsap\USP43, Hsap\FBXL20, Hsap\FBXL7" "viable,fertile" FBgn0036945 Ssk Snakeskin http://flybase.org/reports/FBgn0036945 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O46101 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q0KHY3 establishment of endothelial barrier ; GO:0061028 | inferred from mutant phenotype intestinal epithelial cell development ; GO:0060576 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype anterior midgut development ; GO:0007496 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay smooth septate junction ; GO:0005920 | inferred from direct assay "CT21613, ssk, Ssk, CG6981" - CG6981 11-Aug-17 DroID_v2017_08 - Scer\MPS3 "Cele\nhr-13, Cele\W03C9.2" - - - "viable,partially lethal - majority die,lethal,locomotor behavior defective" "anterior embryonic/larval midgut,smooth septate junctionda.G32" FBgn0035259 CG13932 - http://flybase.org/reports/FBgn0035259 protein_coding_gene - - - CG13932 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262356 CG43054 - http://flybase.org/reports/FBgn0262356 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43054, lincRNA.173" - CG43054 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019695 l(2)k08601 lethal (2) k08601 http://flybase.org/reports/FBgn0019695 - gene - - - l(2)k08601 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" crystal cell FBgn0025921 l(3)78Ad lethal (3) 78Ad http://flybase.org/reports/FBgn0025921 - gene - - - l(3)78Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065453 l(2)SH1396 lethal (2) SH1396 http://flybase.org/reports/FBgn0065453 gene - - - "l(2)SH1396, l(2)SH2 1396" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085750 CR40581 - http://flybase.org/reports/FBgn0085750 rRNA_gene - - - CR40581 - CR40581 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262791 CG43172 - http://flybase.org/reports/FBgn0262791 protein_coding_gene - - - "CG43172, noncoding_5744, nc_5744.a" - CG43172 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000204 bord bordered http://flybase.org/reports/FBgn0000204 - gene - - - bord - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,poor,visible,recessive" "wing,wing vein" FBgn0040688 CG12483 - http://flybase.org/reports/FBgn0040688 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RH38463, CG12483" - CG12483 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0052984 CG32984 - http://flybase.org/reports/FBgn0052984 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG17789, CG32984, gi21430910, gi22945998" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG32984 11-Aug-17 DroID_v2017_08 - - "Cele\T07G12.3, Cele\Y38A10A.2, Cele\Y41E3.1, Cele\T23E1.1, Cele\F07C3.3, Cele\R03G8.1, Cele\F15H10.7, Cele\F10C2.3, Cele\F32G8.2, Cele\R03G8.3, Cele\K03A11.4, Cele\Y73F8A.35, Cele\F32D8.2, Cele\M03F8.5" - - - viable FBgn0029946 CG15034 - http://flybase.org/reports/FBgn0029946 protein_coding_gene - - - CG15034 - CG15034 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001280 janA janus A http://flybase.org/reports/FBgn0001280 FBgn0063739 protein_coding_gene phosphohistidine phosphatase activity ; GO:0008969 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 sex differentiation ; GO:0007548 | inferred from expression pattern peptidyl-histidine dephosphorylation ; GO:0035971 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 "janus, jan, jan A, Jan, Y, BcDNA:AT12574, CG7933, janA" IPR007702:Janus CG7933 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-51e6.1, Drer\phpt1" - Cele\phip-1 Xtro\phpt1 Mmus\Phpt1 Hsap\PHPT1 " adult stage | male , embryonic stage -- adult stage , larval stage--adult stage | male " organism

viable FBgn0039068 CG13827 - http://flybase.org/reports/FBgn0039068 protein_coding_gene - peroxisome fission ; GO:0016559 | inferred from electronic annotation with InterPro:IPR008733 lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of peroxisomal membrane ; GO:0005779 | inferred from electronic annotation with InterPro:IPR008733 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:20208 "BcDNA:RE30473, CG13827, PEX11C" "IPR008733:Peroxisomal biogenesis factor 11, IPR026510:Peroxisomal membrane protein 11C, metazoa" CG13827 11-Aug-17 DroID_v2017_08 "Drer\pex11a, Drer\pex11g, Drer\pex11b" Scer\PEX11 Cele\prx-11 "Xtro\pex11b, Xtro\pex11a, Xtro\pex11g" "Mmus\Pex11g, Mmus\Pex11a, Mmus\Pex11b" "Hsap\PEX11G, Hsap\PEX11B, Hsap\PEX11A" "viable,visible" chaeta FBgn0004240 DptA Diptericin A http://flybase.org/reports/FBgn0004240 - protein_coding_gene - defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity antibacterial humoral response ; GO:0019731 | inferred from expression pattern response to hyperoxia ; GO:0055093 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from direct assay defense response to bacterium ; GO:0042742 | non-traceable author statement positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from expression pattern innate immune response ; GO:0045087 | non-traceable author statement response to bacterium ; GO:0009617 | inferred from expression pattern defense response to bacterium ; GO:0042742 | traceable author statement - "dipt, Dpt, Dipt, 143443_at, DPT, DIPT, DptA, Dip, dpt, CG12763, dip, Dep, DiptA, DIM 27, Dit, diptA" - CG12763 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,partially lethal - majority die,visible" "adult posterior midgut epithelium,mesothoracic tergum" FBgn0065468 l(2)SH1337 lethal (2) SH1337 http://flybase.org/reports/FBgn0065468 gene - - - "l(2)SH1337, l(2)SH2 1337" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004939 ABO-YS Abnormal Oocyte on YS http://flybase.org/reports/FBgn0004939 - region - - - "ABO, ABO-YS" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266865 CR45326 - http://flybase.org/reports/FBgn0266865 non_protein_coding_gene - - - CR45326 - CR45326 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262481 CG43071 - http://flybase.org/reports/FBgn0262481 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43071, lincRNA.347" - CG43071 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053236 Ste:CG33236 Ste:CG33236 http://flybase.org/reports/FBgn0053236 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG32605, CG33236, Ste:CG33236" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33236 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0028604 l(2)W3 lethal (2) W3 http://flybase.org/reports/FBgn0028604 gene - - - "l(2R)W3, l(2)W3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0008653 mn manikin http://flybase.org/reports/FBgn0008653 - gene - - - mn - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male sterile,viable,male,poor" "adult abdomen,adult thorax" FBgn0060976 l(3)S028830 lethal (3) S028830 http://flybase.org/reports/FBgn0060976 gene - - - "0288/30, l(3)S028830" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0259392 C708 - http://flybase.org/reports/FBgn0259392 gene - - - C708 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta,ectopic" FBgn0010009 Amr Amanatin resistant http://flybase.org/reports/FBgn0010009 - gene - - - Amr - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0266961 CR45412 - http://flybase.org/reports/FBgn0266961 non_protein_coding_gene - - - CR45412 - CR45412 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016667 Hrp62 Hrp62 http://flybase.org/reports/FBgn0016667 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "hrp62, Hrp62" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035443 CG12010 - http://flybase.org/reports/FBgn0035443 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960" - - CG12010 "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12010 11-Aug-17 DroID_v2017_08 "Drer\vcp, Drer\zgc:136908, Drer\spata5l1" "Scer\AFG2, Scer\CDC48" - "Xtro\spata5, Xtro\vcp" "Mmus\Vcp, Mmus\Spata5" "Hsap\SPATA5, Hsap\VCP, Hsap\ATAD2B, Hsap\SPATA5L1" "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0027903 CG12018 - http://flybase.org/reports/FBgn0027903 - protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007185 DNA-directed DNA polymerase activity ; GO:0003887 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000045935 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype DNA strand elongation involved in DNA replication ; GO:0006271 | inferred from biological aspect of ancestor with PANTHER:PTN000045935 delta DNA polymerase complex ; GO:0043625 | inferred from biological aspect of ancestor with PANTHER:PTN000045936 microtubule associated complex ; GO:0005875 | inferred from direct assay "BcDNA:HL03874, CG12018, 12018" "IPR007185:DNA polymerase alpha/epsilon, subunit B, IPR024826:DNA polymerase delta/II small subunit family" CG12018 11-Aug-17 DroID_v2017_08 Drer\pold2 Scer\POL31 Cele\F12F6.7 Xtro\pold2 Mmus\Pold2 Hsap\POLD2 "viable,visible" mesothoracic tergum FBgn0052220 Csas CMP-sialic acid synthase http://flybase.org/reports/FBgn0052220 protein_coding_gene N-acylneuraminate cytidylyltransferase activity ; GO:0008781 | inferred from direct assay response to heat ; GO:0009408 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from direct assay "Csas, DmCSAS, CG32220, CSAS" "IPR003329:Acylneuraminate cytidylyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases" CG32220 11-Aug-17 DroID_v2017_08 "Drer\cmasb, Drer\cmasa" - - - Mmus\Cmas Hsap\CMAS "viable,paralytic,neurophysiology defective,locomotor behavior defective,recessive" FBgn0265363 CR44304 - http://flybase.org/reports/FBgn0265363 non_protein_coding_gene - - - CR44304 - CR44304 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025155 ms(2)A12 ms(2)A12 http://flybase.org/reports/FBgn0025155 - gene - - - ms(2)A12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0267041 CR45485 - http://flybase.org/reports/FBgn0267041 non_protein_coding_gene - - - CR45485 - CR45485 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058439 CG40439 - http://flybase.org/reports/FBgn0058439 protein_coding_gene - - - CG40439 - CG40439 11-Aug-17 DroID_v2017_08 Drer\commd8 - - Xtro\commd8 Mmus\Commd8 Hsap\COMMD8 FBgn0261289 CheB98a Chemosensory protein A 98a http://flybase.org/reports/FBgn0261289 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CG14531, CheB98a, CheB98ap" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG14531 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033520 Prx2540-1 Peroxiredoxin 2540-1 http://flybase.org/reports/FBgn0033520 protein_coding_gene peroxiredoxin activity ; GO:0051920 | inferred from electronic annotation with InterPro:IPR019479 peroxidase activity ; GO:0004601 | inferred from direct assay "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 hydrogen peroxide catabolic process ; GO:0042744 | inferred from direct assay" cytosol ; GO:0005829 | inferred from direct assay "CG12405, DPx-2540-1, Prx2540, DPx2540, BEST:LD11278, Prx2540-1, 1-cys peroxiredoxin DPx- 2540-1" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR024706:Peroxiredoxin, AhpC-type, IPR013766:Thioredoxin domain" CG12405 11-Aug-17 DroID_v2017_08 "Drer\prdx4, Drer\prdx1, Drer\prdx2, Drer\prdx3, Drer\prdx6" "Scer\TSA1, Scer\TSA2, Scer\PRX1" "Cele\prdx-6, Cele\prdx-3, Cele\prdx-2" Xtro\prdx6 "Mmus\Prdx2, Mmus\Prdx1, Mmus\Prdx4, Mmus\Prdx3, Mmus\Prdx6b, Mmus\Prdx6" "Hsap\PRDX3, Hsap\PRDX4, Hsap\PRDX6, Hsap\PRDX1, Hsap\PRDX2" FBgn0051315 CG31315 - http://flybase.org/reports/FBgn0051315 protein_coding_gene - - - CG31315 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027313 l(1)G0094 lethal (1) G0094 http://flybase.org/reports/FBgn0027313 - gene - - - l(1)G0094 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority live,female sterile,partially lethal - majority die,recessive" chaeta FBgn0043589 EK2-7 EK2-7 http://flybase.org/reports/FBgn0043589 gene - - - EK2-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052811 CG32811 - http://flybase.org/reports/FBgn0052811 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32811 - CG32811 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22649 K -0.813369712 0.375485171 0.026245544 -0.230067764 -0.501005956 1.50853484 FBgn0015524 otp orthopedia http://flybase.org/reports/FBgn0015524 "FBgn0034559, FBgn0047081" protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 DNA binding ; GO:0003677 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" - "Otp, w26, bk24, W26, CG2965, CG10036, BcDNA:RE58095, otp" "IPR003654:OAR domain, IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG10036 11-Aug-17 DroID_v2017_08 "Drer\otpb, Drer\otpa" - "Cele\npax-3, Cele\npax-1" Xtro\otp "Mmus\Pitx1, Mmus\Pitx2, Mmus\Pitx3, Mmus\Otp" "Hsap\OTP, Hsap\CRX, Hsap\OTX2, Hsap\ARGFX, Hsap\OTX1" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" DRSC04050 IK -0.48409083 -1.871483516 -0.366977855 0.666120827 1.289958843 2.069340552 FBgn0001392 l(1)2Cd lethal (1) 2Cd http://flybase.org/reports/FBgn0001392 - gene - - - l(1)2Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024975 CG2712 - http://flybase.org/reports/FBgn0024975 FBgn0020597 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG2712, anon-3Be, EG:95B7.7, III" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2712 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-77f5.8, Drer\LOC100149413, Drer\LOC101882607" - Cele\ehn-3 - "Mmus\Zfp566, Mmus\Zfp709, Mmus\Zfp81, Mmus\Zfp180, Mmus\Zfp69, Mmus\Zfp558, Mmus\Zfp9, Mmus\Zfp949, Mmus\Peg3, Mmus\Zscan2, Mmus\Zfp952, Mmus\Zfp983, Mmus\Zfp955a, Mmus\Zfp101, Mmus\Zfp157, Mmus\Zfp329, Mmus\Plagl2, Mmus\Zfp78, Mmus\Zfp819, Mmus\Zfp248, Mmus\Zfp882, Mmus\Zfp105, Mmus\Mzf1, Mmus\Zfp37, Mmus\Zfp790, Mmus\Zfp961, Mmus\Zfp763, Mmus\Zfp169, Mmus\2810021J22Rik, Mmus\Zfp955b, Mmus\Zfp810, Mmus\Zfp266, Mmus\A430033K04Rik, Mmus\Gm4924, Mmus\Zfp90" "Hsap\ZNF891, Hsap\ZNF19, Hsap\ZNF133, Hsap\ZFP69, Hsap\ZNF599, Hsap\ZNF705D, Hsap\ZNF619, Hsap\ZNF124, Hsap\ZNF557, Hsap\ZNF425, Hsap\ZNF555, Hsap\ZNF491, Hsap\ZNF559-ZNF177, Hsap\ZNF558, Hsap\ZNF674, Hsap\ZNF266, Hsap\ZNF566, Hsap\ZNF25, Hsap\ZNF589, Hsap\ZNF705B, Hsap\ZNF337, Hsap\ZNF169, Hsap\ZNF554, Hsap\ZFP90, Hsap\ZNF596, Hsap\ZNF705G, Hsap\ZNF35, Hsap\ZNF560, Hsap\ZNF343, Hsap\ZNF620, Hsap\ZNF70, Hsap\PLAGL2, Hsap\ZNF248, Hsap\ZNF684, Hsap\ZNF404, Hsap\ZNF439, Hsap\ZNF529, Hsap\ZFP37, Hsap\ZNF394, Hsap\ZNF705E, Hsap\ZNF329, Hsap\ZSCAN22, Hsap\ZNF77, Hsap\ZNF705A, Hsap\ZNF846, Hsap\ZNF80, Hsap\ZNF556, Hsap\ZNF778, Hsap\ZNF559, Hsap\HKR1, Hsap\ZNF440, Hsap\ZNF69, Hsap\MZF1, Hsap\ZNF180, Hsap\ZNF10, Hsap\ZNF749, Hsap\ZNF550, Hsap\ZNF614, Hsap\ZSCAN2, Hsap\ZNF20, Hsap\ZNF582, Hsap\ZFP69B, Hsap\ZNF669" "viable,fertile" FBgn0003377 Sgs7 Salivary gland secretion 7 http://flybase.org/reports/FBgn0003377 FBgn0036166 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model "sgs7, Sgs-7, sgs-7, 68C GIII, CG18087, Sgs7" - CG18087 11-Aug-17 DroID_v2017_08 - - - - - - larval stage | third instar embryonic/larval salivary gland

viable FBgn0086041 snoRNA:Me18S-A469 - http://flybase.org/reports/FBgn0086041 snoRNA_gene - - - "snoRNA:Me18S-A469, Me18S-Am469, Me18S-A469, CR34670" - CR34670 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001411 l(1)3Da lethal (1) 3Da http://flybase.org/reports/FBgn0001411 - gene - - - "RA55, l(1)3Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" female reproductive system FBgn0017370 l(2)YOa lethal (2) YOa http://flybase.org/reports/FBgn0017370 - gene - - - l(2)YOa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044112 E(rst)C317 E(rst)C317 http://flybase.org/reports/FBgn0044112 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C317, E(rst)C317" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0038946 rdhB retinol dehydrogenase B http://flybase.org/reports/FBgn0038946 protein_coding_gene retinol dehydrogenase activity ; GO:0004745 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG7077, rdhB" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG7077 11-Aug-17 DroID_v2017_08 "Drer\dhrs11b, Drer\dhrs11a, Drer\zgc:153724, Drer\zgc:92630" Scer\YMR226C "Cele\F28H7.2, Cele\H04M03.3" Xtro\dhrs11 Mmus\Dhrs11 Hsap\DHRS11 "neurophysiology defective,viable" "rhabdomere,eye" FBgn0033810 CG4646 - http://flybase.org/reports/FBgn0033810 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD14289, CG4646" "IPR008584:Protein of unknown function DUF866, eukaryotic" CG4646 11-Aug-17 DroID_v2017_08 Drer\si:ch211-284b7.3 Scer\YCR090C Cele\F46B6.12 Xtro\c1orf123 Mmus\0610037L13Rik Hsap\C1orf123 viable FBgn0033672 rho-7 rhomboid-7 http://flybase.org/reports/FBgn0033672 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR002610, InterPro:IPR022764 endopeptidase activity ; GO:0004175 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with Pink1 inferred from physical interaction with HtrA2" mitochondrial fusion ; GO:0008053 | inferred from mutant phenotype protein processing ; GO:0016485 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002610, InterPro:IPR022764 mitochondrion ; GO:0005739 | inferred from direct assay" "CG8972, anon-WO0138581.3, rho-7, PARL, Rhomboid-7, R7, Rho-7" "IPR022764:Peptidase S54, rhomboid domain" CG8972 11-Aug-17 DroID_v2017_08 "Drer\parla, Drer\parl" Scer\PCP1 Cele\rom-5 Xtro\parl Mmus\Parl Hsap\PARL "visible,viable,male sterile,partially lethal - majority die,short lived,uncoordinated,neurophysiology defective" "eye,interommatidial bristle,testis,spermatozoon,mitochondrion,Nebenkern,seminal vesicle,indirect flight muscle,eye photoreceptor cell,rhabdomere" FBgn0003171 pink-wing pink wing http://flybase.org/reports/FBgn0003171 - gene - - - "pink-wing, pw" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,recessive,visible,viable,poor" "pigment cell,wing" FBgn0040350 CG3690 - http://flybase.org/reports/FBgn0040350 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 "EG:BACR7A4.13, anon-WO0140519.250, CG3690" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG3690 11-Aug-17 DroID_v2017_08 "Drer\svopa, Drer\sv2c, Drer\sv2bb, Drer\sv2ba, Drer\svopl, Drer\svopb, Drer\sv2, Drer\sv2a" Scer\HXT9 "Cele\C46C2.2, Cele\Y57G11C.23, Cele\C53B4.1, Cele\svop-1, Cele\ZK892.3" Xtro\sv2b "Mmus\Svopl, Mmus\Sv2b, Mmus\Sv2a, Mmus\Sv2c, Mmus\Svop" "Hsap\SVOP, Hsap\SV2A, Hsap\SV2C, Hsap\SVOPL, Hsap\SV2B" "viable,visible" "chaeta,mesothoracic tergum" FBgn0037037 CG10588 - http://flybase.org/reports/FBgn0037037 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001431 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011237, InterPro:IPR011249" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001431 - CG10588 "IPR001431:Peptidase M16, zinc-binding site, IPR007863:Peptidase M16, C-terminal, IPR011765:Peptidase M16, N-terminal, IPR011249:Metalloenzyme, LuxS/M16 peptidase-like, IPR032632:Peptidase M16, middle/third domain" CG10588 11-Aug-17 DroID_v2017_08 "Drer\nrd1b, Drer\nrd1a, Drer\ide" "Scer\STE23, Scer\AXL1" "Cele\C02G6.1, Cele\Y70C5C.1, Cele\F44E7.4, Cele\C28F5.4, Cele\C02G6.2" Xtro\nrdc "Mmus\Ide, Mmus\Nrd1" "Hsap\NRDC, Hsap\IDE" viable external sensory organ FBgn0265371 CR44312 - http://flybase.org/reports/FBgn0265371 non_protein_coding_gene - - - CR44312 - CR44312 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026400 Noa36 Noa36 http://flybase.org/reports/FBgn0026400 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR010531 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype "midbody ; GO:0030496 | inferred from sequence or structural similarity with UniProtKB:Q9Y3S2 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q9Y3S2 chromosome, centromeric region ; GO:0000775 | inferred from sequence or structural similarity with UniProtKB:Q9Y3S2" "NOA 36, NOA36, CG10009, Noa36, noa36" IPR010531:Zinc finger protein NOA36 CG10009 11-Aug-17 DroID_v2017_08 Drer\znf330 - - Xtro\znf330 Mmus\Zfp330 "Hsap\ZNF836, Hsap\ZNF330" "viable,fertile,partially lethal - majority die,lethal,visible" mesothoracic tergum FBgn0263860 P171 P171 http://flybase.org/reports/FBgn0263860 gene - memory ; GO:0007613 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from mutant phenotype - P171 - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,recessive,memory defective" FBgn0030204 Or9a Odorant receptor 9a http://flybase.org/reports/FBgn0030204 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from direct assay "9a, DOR95, 9E.1, CG15302, Or9a, OR9a, or9a, DmOr9a" "IPR004117:Olfactory receptor, insect" CG15302 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0019669 ms(2)50Ca ms(2)50Ca http://flybase.org/reports/FBgn0019669 - gene - - - ms(2)50Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266391 CR45031 - http://flybase.org/reports/FBgn0266391 non_protein_coding_gene - - - CR45031 - CR45031 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040968 CG14933 - http://flybase.org/reports/FBgn0040968 protein_coding_gene - - - CG14933 IPR002350:Kazal domain CG14933 11-Aug-17 DroID_v2017_08 "Drer\tmeff1b, Drer\tmeff2a, Drer\tmeff2b, Drer\si:dkey-203a12.7" - Cele\ZK813.6 Xtro\tmeff1 "Mmus\Tmeff2, Mmus\Tmeff1" "Hsap\TMEFF2, Hsap\TMEFF1" viable FBgn0034717 CG5819 - http://flybase.org/reports/FBgn0034717 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "tartan/capricious-like, CT18212, CG5819, 5819" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG5819 11-Aug-17 DroID_v2017_08 "Drer\tlr19, Drer\tlr21, Drer\lrrtm1, Drer\lrrtm4l1, Drer\LOC563710, Drer\tlr2, Drer\lrrtm2, Drer\dnaaf1" - Cele\lron-15 Xtro\lrrtm1 "Mmus\Lrrtm1, Mmus\Tlr2, Mmus\Lrrtm4, Mmus\Dnaaf1, Mmus\Lrrtm2, Mmus\Lrrtm3" "Hsap\LRRTM2, Hsap\TLR2, Hsap\LRRTM4, Hsap\DNAAF1, Hsap\LRRTM3, Hsap\NLRC4, Hsap\LRRTM1" viable FBgn0035040 CG4741 - http://flybase.org/reports/FBgn0035040 protein_coding_gene - - - CG4741 - CG4741 11-Aug-17 DroID_v2017_08 - - - - - - DRSC25673 K -0.027019529 -0.015658976 -0.002210613 -0.02466791 -0.047734911 1.596890621 FBgn0264298 CG43776 - http://flybase.org/reports/FBgn0264298 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG43776, CG13569, CG13569-2" "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG43776 11-Aug-17 DroID_v2017_08 "Drer\pi15b, Drer\crispld2, Drer\glipr1b, Drer\crispld1b, Drer\glipr2l, Drer\LOC100536500, Drer\crispld1a, Drer\r3hdml, Drer\glipr2, Drer\pi15a" "Scer\PRY2, Scer\PRY3, Scer\PRY1" "Cele\scl-23, Cele\lon-1" "Xtro\crisp1, Xtro\crispld2, Xtro\r3hdml, Xtro\glipr2, Xtro\MGC108118, Xtro\crisp2, Xtro\crisp3" "Mmus\Glipr1l2, Mmus\Glipr1l1, Mmus\Crisp4, Mmus\Pi15, Mmus\Crisp2, Mmus\Pi16, Mmus\Glipr2, Mmus\Glipr1, Mmus\Crispld2, Mmus\Clec18a, Mmus\Crisp3, Mmus\Crisp1, Mmus\R3hdml, Mmus\Crispld1" "Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\CLEC18A, Hsap\PI16, Hsap\CLEC18B, Hsap\CRISP2, Hsap\CRISPLD1, Hsap\CRISPLD2, Hsap\GLIPR1, Hsap\R3HDML, Hsap\PI15, Hsap\GLIPR2" viable FBgn0259560 GG01554 - http://flybase.org/reports/FBgn0259560 gene - - - GG01554 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "wing cell,wing vein,leg,unguis,antennal segment,arista" FBgn0262538 CG43092 - http://flybase.org/reports/FBgn0262538 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43092 - CG43092 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001348 l(1)1Ec lethal (1) 1Ec http://flybase.org/reports/FBgn0001348 - gene - - - "EA1, 28/6A, l(1)1Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" FBgn0084144 l(2)neo1 lethal (2) neo1 http://flybase.org/reports/FBgn0084144 gene - - - l(2)neo1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041625 Or65a Odorant receptor 65a http://flybase.org/reports/FBgn0041625 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "65a, LU27.2, DOR66, CG32401, Or65a" "IPR004117:Olfactory receptor, insect" CG32401 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08808 K 1.169748629 0.471930075 0.064531934 -0.145232606 0.761275982 -1.715694135 FBgn0266031 CR44796 - http://flybase.org/reports/FBgn0266031 non_protein_coding_gene - - - CR44796 - CR44796 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043070 MESK2 Misexpression suppressor of KSR 2 http://flybase.org/reports/FBgn0043070 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr cellular_component ; GO:0005575 | no biological data available "MESK2, CG15669, l(2)01467, CG15668, BcDNA:RH10174, BcDNA:LD27504, BcDNA:GH12032, mesk2, Mesk2" "IPR004142:NDRG, IPR029058:Alpha/Beta hydrolase fold" CG15669 11-Aug-17 DroID_v2017_08 "Drer\ndrg4, Drer\ndrg1a, Drer\ndrg2, Drer\ndrg3b, Drer\ndrg1b, Drer\ndrg3a" - "Cele\ZK1073.1, Cele\Y48G10A.3" "Xtro\ndrg1, Xtro\ndrg3, Xtro\ndrg4, Xtro\ndrg2" "Mmus\Ndrg1, Mmus\Ndrg4, Mmus\Ndrg3, Mmus\Ndrg2" "Hsap\NDRG2, Hsap\NDRG4, Hsap\NDRG1, Hsap\NDRG3" "viable,fertile,lethal,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,wing vein" FBgn0043902 fad fat-head http://flybase.org/reports/FBgn0043902 gene - - - fad - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262127 kibra kibra http://flybase.org/reports/FBgn0262127 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with sav protein binding ; GO:0005515 | inferred from physical interaction with Mer protein binding ; GO:0005515 | inferred from physical interaction with ex inferred from physical interaction with wts inferred from physical interaction with Mer "regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype inferred from genetic interaction with ex inferred from genetic interaction with Mer inferred from genetic interaction with hpo regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype inferred from genetic interaction with ex inferred from genetic interaction with sav inferred from genetic interaction with Mer inferred from genetic interaction with hpo border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of glial cell proliferation ; GO:0060253 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with crb regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype inferred from genetic interaction with yki inferred from genetic interaction with hpo" Kibra-Ex-Mer complex ; GO:0036375 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "kib, kibra, kbr, CG33967, Kibra, CG7552, RE26350, CG12600, l(3)02404, l(3)j5C3, l(3)neo42, ORE-2, Kib, DmKibra" "IPR000008:C2 domain, IPR001202:WW domain" CG33967 11-Aug-17 DroID_v2017_08 "Drer\magixa, Drer\nedd4l, Drer\smurf1, Drer\hecw1b, Drer\LOC100334952, Drer\hecw2b, Drer\yap1, Drer\hecw2a, Drer\LOC564220, Drer\itcha, Drer\LOC556872, Drer\wwtr1, Drer\magi3a, Drer\wwp2, Drer\magi2a, Drer\bag3, Drer\nedd4a, Drer\magi1a, Drer\magi2b, Drer\wwc1, Drer\smurf2, Drer\wwc3" "Scer\RSP5, Scer\TOM1" - "Xtro\nedd4, Xtro\wwc1, Xtro\wwc2, Xtro\nedd4l, Xtro\hecw1, Xtro\wwp2, Xtro\smurf1, Xtro\wwc3, Xtro\bag3, Xtro\itch, Xtro\magi1, Xtro\magi3" "Mmus\Nedd4l, Mmus\Wwp2, Mmus\Nedd4, Mmus\Gas7, Mmus\Itch, Mmus\Smurf2, Mmus\Wwc1, Mmus\Magix, Mmus\Yap1, Mmus\Smurf1, Mmus\Magi3, Mmus\Hecw1, Mmus\Bag3, Mmus\Wwc2, Mmus\Wwp1, Mmus\Hecw2, Mmus\Magi1" "Hsap\MAGI1, Hsap\WWC1, Hsap\NEDD4L, Hsap\WWP1, Hsap\WWC2, Hsap\HECW2, Hsap\SMURF1, Hsap\SMURF2, Hsap\NEDD4, Hsap\ITCH, Hsap\WWC3, Hsap\MAGI3, Hsap\GAS7, Hsap\BAG3, Hsap\HECW1, Hsap\YAP1, Hsap\WWP2, Hsap\MAGIX" FBgn0065957 l(2)SH0053 lethal (2) SH0053 http://flybase.org/reports/FBgn0065957 gene - - - "l(2)SH0053, l(2)SH2 0053" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263955 BG01042 - http://flybase.org/reports/FBgn0263955 gene - - - BG01042 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,short lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0022296 l(1)M52.3 lethal (1) M52.3 http://flybase.org/reports/FBgn0022296 - gene - - - "M52.3, l(1)M52.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024833 AP-1mu "Adaptor Protein complex 1, mu subunit" http://flybase.org/reports/FBgn0024833 - protein_coding_gene clathrin binding ; GO:0030276 | inferred from sequence or structural similarity with SGD:S000006180 protein transporter activity ; GO:0008565 | inferred from mutant phenotype "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001392, InterPro:IPR018240 neurotransmitter secretion ; GO:0007269 | non-traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype vesicle coating ; GO:0006901 | traceable author statement vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with SGD:S000006180 secretory granule organization ; GO:0033363 | inferred from mutant phenotype synaptic vesicle coating ; GO:0016183 | traceable author statement negative regulation of endocytic recycling ; GO:2001136 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with Dl inferred from genetic interaction with Ser inferred from genetic interaction with spdo intracellular transport ; GO:0046907 | inferred from mutant phenotype" synaptic vesicle ; GO:0008021 | traceable author statement clathrin-coated vesicle ; GO:0030136 | inferred from direct assay AP-1 adaptor complex ; GO:0030121 | inferred from mutant phenotype inferred from physical interaction with AP-1γ transcription factor AP-1 complex ; GO:0035976 | inferred from mutant phenotype inferred from physical interaction with AP-1γ AP-1 adaptor complex ; GO:0030121 | inferred from sequence or structural similarity with SGD:S000006180 coated vesicle ; GO:0030135 | traceable author statement "cg9388, CG9388, mu1, AP47, Dmu1, AP-1mu, AP-47, AP-1mu1, apm1, AP1mu1, APmu1, ap-47" "IPR001392:Clathrin adaptor, mu subunit, IPR011012:Longin-like domain, IPR018240:Clathrin adaptor, mu subunit, conserved site, IPR028565:Mu homology domain, IPR022775:AP complex, mu/sigma subunit" CG9388 11-Aug-17 DroID_v2017_08 "Drer\ldlrb, Drer\ap1m2, Drer\ap4m1, Drer\ap1m1, Drer\ap2m1a, Drer\ap1m3, Drer\ap2m1b, Drer\ap5m1" "Scer\APM4, Scer\APM2, Scer\APM3, Scer\APM1" "Cele\unc-41, Cele\dpy-23, Cele\apm-1, Cele\unc-101" "Xtro\ap1m1, Xtro\ap1m2, Xtro\ap2m1, Xtro\ap5m1, Xtro\ap4m1" "Mmus\Ap5m1, Mmus\Ap1m1, Mmus\Ap2m1, Mmus\Ap1m2, Mmus\Ap4m1" "Hsap\AP1M2, Hsap\AP4M1, Hsap\AP2M1, Hsap\AP1M1, Hsap\AP5M1" embryonic stage -- adult stage "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,body color defective" "eye,somatic clone,tormogen cell,supernumerary,embryonic/larval salivary gland,secretory granule,embryonic/larval salivary gland | third instar larval stage,secretory granuleAB1,ommatidium,mesothoracic tergum" FBgn0031375 erm earmuff http://flybase.org/reports/FBgn0031375 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype stem cell population maintenance ; GO:0019827 | inferred from mutant phenotype" - "CG7312, erm, CG31670, dfezl, dFezf" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31670 11-Aug-17 DroID_v2017_08 "Drer\znf296, Drer\prdm12b, Drer\LOC100537687, Drer\fezf1, Drer\si:dkey-33c14.6, Drer\gfi1aa, Drer\gfi1b, Drer\egr2b, Drer\fezf2, Drer\zgc:113377, Drer\zbtb49, Drer\gfi1ab, Drer\osr1, Drer\znf668, Drer\sp3b, Drer\zgc:136308, Drer\osr2" Scer\AZF1 "Cele\ZK686.5, Cele\klu-1, Cele\eor-1, Cele\Y111B2A.10, Cele\ztf-6, Cele\fezf-1, Cele\zfp-2" "Xtro\sp5l, Xtro\fezf2, Xtro\fezf1, Xtro\znf630, Xtro\osr1, Xtro\znf33b, Xtro\hic1, Xtro\osr2" "Mmus\Zscan4d, Mmus\Zfp9, Mmus\Zfp992, Mmus\Gfi1, Mmus\Osr2, Mmus\2810021J22Rik, Mmus\Zscan4b, Mmus\Osr1, Mmus\9130019O22Rik, Mmus\Zfp991, Mmus\Zfp446, Mmus\Zic5, Mmus\Prdm12, Mmus\Fezf1, Mmus\Zscan4c, Mmus\Zfp444, Mmus\Fezf2, Mmus\Gfi1b, Mmus\Zscan4f, Mmus\Zscan5b" "Hsap\FEZF2, Hsap\OSR1, Hsap\FEZF1, Hsap\ZNF764, Hsap\PRDM1, Hsap\GFI1, Hsap\OSR2, Hsap\ZNF683, Hsap\PRDM12, Hsap\ZNF444, Hsap\ZNF500, Hsap\ZNF467, Hsap\GFI1B" "neuroanatomy defective,somatic clone,lethal,viable,fertile" "type II neuroblast | third instar larval stage,type II neuroblast,somatic clone,supernumerary,supernumerary | third instar larval stage,embryonic/larval neuroblast,ectopic" FBgn0003180 pyp polyphene http://flybase.org/reports/FBgn0003180 - gene - - - pyp - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,partially lethal - majority live" "eye,wing,3rd posterior cell,trident,male" FBgn0086290 GS5036 - http://flybase.org/reports/FBgn0086290 gene - - - "GS5036, 5036" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060762 l(3)S063218 lethal (3) S063218 http://flybase.org/reports/FBgn0060762 gene - - - "0632/18, l(3)S063218" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0259351 C79 - http://flybase.org/reports/FBgn0259351 gene - - - C79 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing hair FBgn0028098 l(3)S073615 lethal (3) S073615 http://flybase.org/reports/FBgn0028098 gene - - - "0736/15, l(3)S073615" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0067062 O4 O4 http://flybase.org/reports/FBgn0067062 gene - - - O4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable" FBgn0044442 HMS-Beagle\gag HMS-Beagle element gag http://flybase.org/reports/FBgn0044442 transposable_element_gene - - - HMS-Beagle\gag - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051719 RluA-1 RluA-1 http://flybase.org/reports/FBgn0051719 protein_coding_gene "pseudouridine synthase activity ; GO:0009982 | inferred from electronic annotation with InterPro:IPR006145, InterPro:IPR006224, InterPro:IPR006225, InterPro:IPR020103 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR006145, InterPro:IPR006224, InterPro:IPR006225, InterPro:IPR020103" "pseudouridine synthesis ; GO:0001522 | inferred from electronic annotation with InterPro:IPR006145, InterPro:IPR006224, InterPro:IPR006225, InterPro:IPR020103" - "RluA1, CG31719, CG7475, CG13143, RluA-1" "IPR006145:Pseudouridine synthase, RsuA/RluB/C/D/E/F, IPR006224:Pseudouridine synthase, RluC/RluD, conserved site, IPR006225:Pseudouridine synthase, RluC/RluD, IPR020103:Pseudouridine synthase, catalytic domain" CG31719 11-Aug-17 DroID_v2017_08 "Drer\rpusd4, Drer\rpusd2, Drer\rpusd1" "Scer\PUS9, Scer\PUS6, Scer\PUS5, Scer\RIB2" Cele\K07E8.7 "Xtro\rpusd2, Xtro\rpusd3, Xtro\rpusd1" "Mmus\Rpusd3, Mmus\Rpusd2, Mmus\Rpusd4, Mmus\Rpusd1" "Hsap\RPUSD4, Hsap\RPUSD1, Hsap\RPUSD3, Hsap\RPUSD2" "viable,fertile" FBgn0070029 BG00158 BG00158 http://flybase.org/reports/FBgn0070029 gene - - - BG00158 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0084500 lep leprechaun http://flybase.org/reports/FBgn0084500 gene - - - "E-3c, lep" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260656 CG42539 - http://flybase.org/reports/FBgn0260656 protein_coding_gene - - - "CG42539, HCD15482" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060894 l(3)S044437 lethal (3) S044437 http://flybase.org/reports/FBgn0060894 gene - - - "0444/37, l(3)S044437" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065887 l(2)SH0226 lethal (2) SH0226 http://flybase.org/reports/FBgn0065887 gene - - - "l(2)SH0226, l(2)SH2 0226" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010034 E(var)7 Enhancer of variegation http://flybase.org/reports/FBgn0010034 - gene - - - "Evar7, E(var)7" - - 11-Aug-17 DroID_v2017_08 - - - - - - enhancer of variegation FBgn0053746 snmRNA:430:CR33746 snmRNA:430:CR33746 http://flybase.org/reports/FBgn0053746 non_protein_coding_gene - - - "CR33746, snmRNA:430:CR33746" - CR33746 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027176 l(2)60Ah lethal (2) 60Ah http://flybase.org/reports/FBgn0027176 - gene - - - "ET/141, l(2)60Ah" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065847 l(2)SH0315 lethal (2) SH0315 http://flybase.org/reports/FBgn0065847 gene - - - "l(2)SH0315, l(2)SH2 0315" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085455 CG34426 - http://flybase.org/reports/FBgn0085455 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG34426, CG13307" IPR002557:Chitin binding domain CG34426 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043782 Burdock\gag Burdock element gag http://flybase.org/reports/FBgn0043782 transposable_element_gene - - - Burdock\gag - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085813 18SrRNA-Psi:CR41602 18S ribosomal RNA pseudogene:CR41602 http://flybase.org/reports/FBgn0085813 pseudogene_attribute - - - "CR41602, 18SrRNA-Psi:CR41602" - CR41602 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065404 l(2)SH1594 lethal (2) SH1594 http://flybase.org/reports/FBgn0065404 gene - - - "l(2)SH1594, l(2)SH2 1594" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003380 Sh Shaker http://flybase.org/reports/FBgn0003380 "FBgn0030885, FBgn0030888, FBgn0064981" protein_coding_gene "voltage-gated potassium channel activity ; GO:0005249 | inferred from electronic annotation with InterPro:IPR003968, InterPro:IPR003972, InterPro:IPR004048, InterPro:IPR028325 voltage-gated cation channel activity ; GO:0022843 | inferred from direct assay voltage-gated potassium channel activity ; GO:0005249 | non-traceable author statement voltage-gated potassium channel activity ; GO:0005249 | traceable author statement" "protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR003968, InterPro:IPR003972, InterPro:IPR004048, InterPro:IPR028325 regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype positive regulation of membrane potential ; GO:0045838 | inferred from mutant phenotype positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype detection of visible light ; GO:0009584 | inferred from mutant phenotype behavioral response to ether ; GO:0048150 | non-traceable author statement sleep ; GO:0030431 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | non-traceable author statement learning or memory ; GO:0007611 | non-traceable author statement regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype mating behavior, sex discrimination ; GO:0048047 | inferred from direct assay action potential ; GO:0001508 | inferred from mutant phenotype courtship behavior ; GO:0007619 | traceable author statement potassium ion transport ; GO:0006813 | traceable author statement cellular response to dopamine ; GO:1903351 | inferred from mutant phenotype proboscis extension reflex ; GO:0007637 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement" voltage-gated potassium channel complex ; GO:0008076 | traceable author statement integral component of membrane ; GO:0016021 | inferred from direct assay voltage-gated potassium channel complex ; GO:0008076 | non-traceable author statement voltage-gated potassium channel complex ; GO:0008076 | inferred from physical interaction with Hk "Sh, sh, EKO, SH, CG12348, V-I, Sha, Shw, CG7640, minisleep, F-c, CG17860, BcDNA:GH03046, Eko, Shaker, Kv1, sha, K[[v]]1" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR003968:Potassium channel, voltage dependent, Kv, IPR003972:Potassium channel, voltage dependent, Kv1, IPR005821:Ion transport domain, IPR028325:Voltage-gated potassium channel, IPR004048:Potassium channel, voltage dependent, Kv1.1" CG12348 11-Aug-17 DroID_v2017_08 "Drer\LOC100004160, Drer\kcna1l, Drer\kcna4, Drer\kcna2b, Drer\knca7, Drer\si:ch73-334d15.4, Drer\LOC100330283, Drer\kcna6a, Drer\LOC100537815, Drer\kcna1a, Drer\kcna3a" - "Cele\C32C4.1, Cele\shk-1, Cele\exp-2, Cele\kvs-1, Cele\kvs-5, Cele\kvs-3, Cele\kvs-4" "Xtro\kcna3, Xtro\kcna6, Xtro\kcna7, Xtro\kcna4, Xtro\kcna1, Xtro\kcna10" "Mmus\Kcna2, Mmus\Kcna5, Mmus\Kcna6, Mmus\Kcna3, Mmus\Kcna10, Mmus\Kcna4, Mmus\Kcna7, Mmus\Kcna1" "Hsap\KCNA4, Hsap\KCNA5, Hsap\KCNA6, Hsap\KCNA7, Hsap\KCNA3, Hsap\KCNA10, Hsap\KCNA2, Hsap\KCNA1" "courtship behavior defective,viable,fertile,behavior defective,dominant,uncoordinated,short lived,neurophysiology defective,locomotor behavior defective,chemical sensitive,hyperactive,lethal,recessive,taste perception defective,smell perception defective,visible,chemical resistant,male,chemosensitive behavior defective,RU486 conditional,visual behavior defective,cold sensitive,body color defective,circadian behavior defective,sleep defective,flight defective,locomotor rhythm defective" "axon & motor neuron | conditional ts,giant fiber neuron,neuromuscular junction,synapse,end plate,photoreceptor cell,muscle fiber,wing,adult thorax,leg,embryonic/larval neuromuscular junction,photoreceptor,presumptive embryonic/larval muscle system,embryonic/larval neuron,motor neuron,eye,adult cuticle,larval head,cold sensitive,abdomen | adult stage A1,RU486 conditional" FBgn0001779 l(1)M64 lethal (1) M64 http://flybase.org/reports/FBgn0001779 - gene - - - l(1)M64 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0002290 l(3)80Fa lethal (3) 80Fa http://flybase.org/reports/FBgn0002290 - gene - - - "l8, l(3)Lh8, l(3)80Fa, 80Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038105 yellow-f2 yellow-f2 http://flybase.org/reports/FBgn0038105 protein_coding_gene dopachrome isomerase activity ; GO:0004167 | inferred from direct assay melanin biosynthetic process from tyrosine ; GO:0006583 | traceable author statement developmental pigmentation ; GO:0048066 | inferred by curator from GO:0004167 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 melanin biosynthetic process from tyrosine ; GO:0006583 | inferred by curator from GO:0004167 developmental pigmentation ; GO:0048066 | traceable author statement indole-containing compound biosynthetic process ; GO:0042435 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG8063, yellow-f2, yel-f2" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG8063 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\fbxa-76, Cele\C24H12.1, Cele\F49E11.8, Cele\T27A1.3" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 viable FBgn0034628 Acox57D-p acyl-Coenzyme A oxidase at 57D proximal http://flybase.org/reports/FBgn0034628 protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012258, InterPro:IPR013786 acyl-CoA oxidase activity ; GO:0003997 | inferred from sequence or structural similarity with HGNC:119" fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:119 "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:119,HGNC:120 inferred from sequence model" "acox, D-acox, CG9707, Acox57Dp, Acox57D-p" "IPR002655:Acyl-CoA oxidase, C-terminal, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR012258:Acyl-CoA oxidase, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR029320:Acyl-coenzyme A oxidase, N-terminal" CG9707 11-Aug-17 DroID_v2017_08 "Drer\acox1, Drer\acox3" Scer\POX1 "Cele\acox-4, Cele\acox-1, Cele\F59F4.1, Cele\acox-5, Cele\acox-3, Cele\acox-2, Cele\acdh-13" "Xtro\acox2, Xtro\acox1" "Mmus\Acox1, Mmus\Acox2, Mmus\Acox3" "Hsap\ACOX1, Hsap\ACOX2, Hsap\ACOX3" FBgn0014868 Ost48 Oligosaccharyltransferase 48kD subunit http://flybase.org/reports/FBgn0014868 FBgn0026008 protein_coding_gene - protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from electronic annotation with InterPro:IPR005013 neurogenesis ; GO:0022008 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR005013 endomembrane system ; GO:0012505 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Ots48, CG9022, OST48/WBP1, DrOST, OST48, DmOST50, clone 1.11, anon-EST:Liang-1.11, Ost48, ost48, OST" "IPR005013:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, IPR029062:Class I glutamine amidotransferase-like" CG9022 11-Aug-17 DroID_v2017_08 Drer\ddost Scer\WBP1 Cele\ostb-1 Xtro\ddost Mmus\Ddost Hsap\DDOST "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0001691 l(1)ESHS12 lethal (1) ESHS12 http://flybase.org/reports/FBgn0001691 - gene - - - l(1)ESHS12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022945 CFDD Common regulatory Factor for DNA replication and DREF genes http://flybase.org/reports/FBgn0022945 - gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay CFDD - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014092 CG4278 - http://flybase.org/reports/FBgn0014092 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000351096 "un5, BG:DS02740.16, anon-35F/36A, CG4278" IPR002678:GTP cyclohydrolase 1 type 2/Nif3 CG4278 11-Aug-17 DroID_v2017_08 "Drer\ciao1, Drer\nif3l1" Scer\NIF3 Cele\Y18D10A.9 "Xtro\nif3l1, Xtro\LOC101733905, Xtro\ciao1" "Mmus\Ciao1, Mmus\Nif3l1" "Hsap\CIAO1, Hsap\NIF3L1" embryonic stage | early viable FBgn0028496 CG30116 - http://flybase.org/reports/FBgn0028496 protein_coding_gene - - - "BcDNA:GH04922, CG5512, CG17671, CG30116" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR017986:WD40-repeat-containing domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG30116 11-Aug-17 DroID_v2017_08 "Drer\LOC101885341, Drer\nwd1" "Scer\CDC4, Scer\PRP46" "Cele\T05C3.2, Cele\qui-1" - "Mmus\Wdr27, Mmus\Ttc41, Mmus\Nwd1" "Hsap\NWD1, Hsap\WDR27" "viable,fertile" FBgn0021819 l(2)k16215 lethal (2) k16215 http://flybase.net/reports/FBgn0021819.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" crystal cell FBgn0051418 CG31418 - http://flybase.org/reports/FBgn0051418 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG5329, CG31418" - CG31418 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264714 CG43982 - http://flybase.org/reports/FBgn0264714 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43982 - CG43982 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015780 Onf-AATAA Ovarian nuclear factor-AATAA http://flybase.org/reports/FBgn0015780 - gene - - - "ONF-AATAA, Onf-AATAA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265719 CR44526 - http://flybase.org/reports/FBgn0265719 non_protein_coding_gene - - - "incRNA.476, CR44526, lincRNA.476" - CR44526 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050145 Obp57e Odorant-binding protein 57e http://flybase.org/reports/FBgn0050145 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush transport ; GO:0006810 | non-traceable author statement sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "CG13429, Obp57d, 57e, OBP57e, CG30145, Obp57e, Dmel\Obp57e, DmelObp57e" IPR006170:Pheromone/general odorant binding protein CG30145 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040103 lectin-24Da lectin-24Da http://flybase.org/reports/FBgn0040103 gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity - - "AC004279a, AC 004279A, lectin-24Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000373 cripB crippled B http://flybase.org/reports/FBgn0000373 - gene - - - cripB - - 11-Aug-17 DroID_v2017_08 - - - - - - "hypoactive,visible,uncoordinated" eye FBgn0039850 CG11333 - http://flybase.org/reports/FBgn0039850 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000868 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000868 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001797383 "BcDNA:AT02774, CG11333" IPR000868:Isochorismatase-like CG11333 11-Aug-17 DroID_v2017_08 "Drer\isoc2, Drer\isoc1" - Cele\marb-1 "Xtro\isoc2, Xtro\isoc1" "Mmus\Isoc2a, Mmus\Isoc1, Mmus\Isoc2b" "Hsap\ISOC2, Hsap\ISOC1" viable FBgn0002655 mat(2)cell-D maternal effect cellularisation defect D http://flybase.org/reports/FBgn0002655 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)cellPQ49, mat(2)cell-D" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0266399 CR45039 - http://flybase.org/reports/FBgn0266399 non_protein_coding_gene - - - CR45039 - CR45039 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034187 CG6967 - http://flybase.org/reports/FBgn0034187 protein_coding_gene - - - "CT21565, CG6967" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026127:Probable RNA helicase SDE3" CG6967 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97a13.6, Drer\mov10b.2, Drer\znfx1, Drer\mov10b.1, Drer\mov10a, Drer\zgc:154086, Drer\helz2" "Scer\HCS1, Scer\NAM7" "Cele\eri-7, Cele\ZK1067.2" "Xtro\mov10l1, Xtro\mov10, Xtro\helz" "Mmus\Znfx1, Mmus\Helz, Mmus\Mov10, Mmus\Mov10l1, Mmus\Helz2" "Hsap\HELZ, Hsap\HELZ2, Hsap\ZNFX1, Hsap\MOV10L1, Hsap\MOV10" "viable,fertile" FBgn0063647 CE2-2 "Calcineurin enhancer, chromosome 2, group 2" http://flybase.org/reports/FBgn0063647 gene - - - CE2-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022366 Pt-7 Larval protein-7 http://flybase.org/reports/FBgn0022366 - gene - - - Pt-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265194 Trpm "Transient receptor potential cation channel, subfamily M" http://flybase.org/reports/FBgn0265194 protein_coding_gene "cation channel activity ; GO:0005261 | inferred from direct assay intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity ; GO:0097682 | inferred from direct assay metal ion transmembrane transporter activity ; GO:0046873 | inferred from direct assay" protein tetramerization ; GO:0051262 | inferred from electronic annotation with InterPro:IPR032415 divalent metal ion transport ; GO:0070838 | inferred from direct assay zinc ion homeostasis ; GO:0055069 | inferred from mutant phenotype cell growth ; GO:0016049 | inferred from mutant phenotype magnesium ion homeostasis ; GO:0010960 | inferred from mutant phenotype cation transmembrane transport ; GO:0098655 | inferred from direct assay mitochondrion organization ; GO:0007005 | inferred from mutant phenotype thermotaxis ; GO:0043052 | NOT inferred from mutant phenotype cation channel complex ; GO:0034703 | inferred from direct assay "CG44240, Trpm, trpm, CG34187, CG34123, CG30079, CG30078, TrpM, TRPM, CG16805, BcDNA:GH04950, dTRPM, DmTRPM, mdcds_11815" "IPR005821:Ion transport domain, IPR020683:Ankyrin repeat-containing domain, IPR032415:TRPM, tetramerisation domain" CG44240 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-173d10.1, Drer\trpm4b.1, Drer\trpm5, Drer\trpm7, Drer\trpm4b.2, Drer\trpm2, Drer\trpm6, Drer\trpm4a, Drer\trpm3, Drer\trpm1a, Drer\trpm1b" - "Cele\trpl-2, Cele\gtl-2, Cele\trpl-4, Cele\F13B12.3, Cele\trpl-3, Cele\gon-2, Cele\trpl-5, Cele\gtl-1" "Xtro\trpm6, Xtro\trpm3, Xtro\trpm8, Xtro\LOC100491139, Xtro\trpm4, Xtro\trpm1, Xtro\trpm7" "Mmus\Trpm1, Mmus\Trpm5, Mmus\Trpm3, Mmus\Trpm2, Mmus\Trpm7, Mmus\Trpm6, Mmus\Trpm4, Mmus\Trpm8" "Hsap\TRPM5, Hsap\TRPM3, Hsap\TRPM1, Hsap\TRPM4, Hsap\TRPM7, Hsap\TRPM6, Hsap\TRPM2, Hsap\TRPM8" FBgn0085235 CG34206 - http://flybase.org/reports/FBgn0085235 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34206 - CG34206 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028387 chm chameau http://flybase.org/reports/FBgn0028387 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002515 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR002515 transcription factor binding ; GO:0008134 | inferred from physical interaction with Jra inferred from physical interaction with kay histone acetyltransferase activity ; GO:0004402 | traceable author statement H3 histone acetyltransferase activity ; GO:0010484 | inferred from direct assay H4 histone acetyltransferase activity ; GO:0010485 | inferred from direct assay transcription coactivator activity ; GO:0003713 | inferred from direct assay" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay chaeta development ; GO:0022416 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from mutant phenotype histone H3 acetylation ; GO:0043966 | inferred from direct assay neuron development ; GO:0048666 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype negative regulation of cell fate specification ; GO:0009996 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from genetic interaction with Pc gene silencing ; GO:0016458 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "chm, HAT1, dmHAG404, CG5229, HAT, HBO1, Chm" "IPR002515:Zinc finger, C2HC-type, IPR002717:Histone acetyltransferase domain, MYST-type, IPR016181:Acyl-CoA N-acyltransferase" CG5229 11-Aug-17 DroID_v2017_08 "Drer\kat5b, Drer\kat5a, Drer\kat8, Drer\kat7a, Drer\kat7b, Drer\kat6a, Drer\kat6b" "Scer\SAS3, Scer\SAS2, Scer\ESA1" "Cele\mys-2, Cele\mys-1, Cele\mys-4, Cele\lsy-12" "Xtro\kat8, Xtro\trim69.1, Xtro\kat7, Xtro\xnf7, Xtro\kat5" "Mmus\Kat8, Mmus\Kat7, Mmus\Kat6a, Mmus\Kat5, Mmus\Kat6b" "Hsap\KAT8, Hsap\KAT7, Hsap\KAT6A, Hsap\KAT6B, Hsap\KAT5" "suppressor of variegation,dominant,lethal - all die before end of pupal stage,recessive,some die during pupal stage,wild-type,viable" adult thorax DRSC24941 K -0.371367026 -0.347656926 0.370704248 0.530648663 -1.502221657 0.153279396 FBgn0039840 pHCl-2 pH-sensitive chloride channel 2 http://flybase.org/reports/FBgn0039840 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 chloride channel activity ; GO:0005254 | inferred from direct assay pH-gated chloride channel activity ; GO:0061797 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "CG11340, CT5896, Lcch-100C, lincRNA.914, pHCl-2" "IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000:Neurotransmitter-gated ion-channel, conserved site" CG11340 11-Aug-17 DroID_v2017_08 "Drer\glra4a, Drer\glra3, Drer\glra1, Drer\glrbb, Drer\glra4b, Drer\glra2, Drer\glrba" - "Cele\glc-1, Cele\glc-3, Cele\lgc-54, Cele\lgc-53, Cele\mod-1, Cele\acc-4, Cele\lgc-47, Cele\glc-2, Cele\lgc-55, Cele\lgc-50, Cele\acc-2, Cele\lgc-38, Cele\lgc-46, Cele\pbo-5, Cele\avr-14, Cele\lgc-52, Cele\ggr-3, Cele\avr-15, Cele\lgc-51, Cele\glc-4, Cele\acc-3, Cele\acc-1, Cele\lgc-49, Cele\lgc-48" "Xtro\glra1, Xtro\glra2, Xtro\glra3, Xtro\glrb" "Mmus\Glra4, Mmus\Glra1, Mmus\Glrb, Mmus\Glra3, Mmus\Glra2, Mmus\Gabrp" "Hsap\GLRA2, Hsap\GLRA4, Hsap\GLRB, Hsap\GLRA3, Hsap\GABRP, Hsap\GLRA1" "viable,fertile" DRSC14306 EK 1.016128472 0.681938305 1.863558529 1.254861527 0.556120495 1.730679265 FBgn0036220 CG5897 - http://flybase.org/reports/FBgn0036220 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG5897 IPR002557:Chitin binding domain CG5897 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\R02F2.4, Cele\cpg-2, Cele\cpg-1, Cele\C39D10.7" - - Hsap\MATN2 "partially lethal - majority die,some die during pupal stage" FBgn0051976 ovm oven mitt http://flybase.org/reports/FBgn0051976 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG31976, CG11623, ovm" IPR010512:Protein of unknown function DUF1091 CG31976 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0005124 l(1)J1743 lethal (1) J1743 http://flybase.org/reports/FBgn0005124 - gene - - - l(1)J1743 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0069132 mei(2)yh149 mei(2)yh149 http://flybase.org/reports/FBgn0069132 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(2)yh149 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,female fertile" FBgn0003670 tbl tasteblind http://flybase.org/reports/FBgn0003670 - gene - - - tbl - - 11-Aug-17 DroID_v2017_08 - - - - - - chemosensitive behavior defective FBgn0259627 B2033 - http://flybase.org/reports/FBgn0259627 gene - - - B2033 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0036196 CG11658 - http://flybase.org/reports/FBgn0036196 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "anon-WO0118547.413, CG11658, FBXO12" IPR001810:F-box domain CG11658 11-Aug-17 DroID_v2017_08 "Drer\fbxo25, Drer\fbxo32, Drer\lypla2" - "Cele\mfb-1, Cele\ath-1" "Xtro\lypla1, Xtro\lypla2, Xtro\fbxo32, Xtro\fbxo25" "Mmus\Lypla2, Mmus\Fbxo25, Mmus\Fbxo32, Mmus\Lypla1" "Hsap\FBXO25, Hsap\LYPLA1, Hsap\FBXO32, Hsap\LYPLA2, Hsap\FBXO7" "viable,fertile" FBgn0024368 CG18091 - http://flybase.org/reports/FBgn0024368 FBgn0029572 protein_coding_gene - - - "EG:190E7.1, CG18091" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005213 l(3)ET4 lethal Elaine Tasaka 4 http://flybase.org/reports/FBgn0005213 - gene - - - l(3)ET4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cold sensitive,heat sensitive" FBgn0050379 CG30379 - http://flybase.org/reports/FBgn0050379 protein_coding_gene - - - CG30379 IPR006214:Bax inhibitor 1-related CG30379 11-Aug-17 DroID_v2017_08 "Drer\LOC566927, Drer\tmbim1, Drer\grinaa, Drer\tmbim4, Drer\grinab, Drer\si:ch211-284o19.8, Drer\faim2a, Drer\faim2b, Drer\zgc:110410" Scer\BXI1 "Cele\xbx-6, Cele\Y42H9AR.2, Cele\tmbi-4, Cele\tag-120" "Xtro\tmbim1, Xtro\faim2, Xtro\tmbim4" "Mmus\Grina, Mmus\Tmbim4, Mmus\Tmbim7, Mmus\Tmbim1, Mmus\Faim2" "Hsap\FAIM2, Hsap\TMBIM1, Hsap\GRINA, Hsap\TMBIM4" viable FBgn0041760 efe efendi http://flybase.org/reports/FBgn0041760 gene - - - efe - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,recessive,lethal - all die before end of pupal stage,partially,some die during pupal stage,chemical resistant,dominant" "polytene chromosome,melanotic mass,embryonic/larval brain,salivary gland" FBgn0016799 l(1)44 lethal (1) 44 http://flybase.org/reports/FBgn0016799 - gene - - - l(1)44 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0024680 l(1)LefEM26 lethal (1) LefEM26 http://flybase.org/reports/FBgn0024680 - gene - - - "EM26, l(1)LefEM26" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043457 CG5180 - http://flybase.org/reports/FBgn0043457 protein_coding_gene - - - "LD05530, BEST:LD05530, CG5180" IPR006578:MADF domain CG5180 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable" "dorsocentral bristle,scutellar bristle,trichogen cell,ectopic,thecogen cell" FBgn0062573 Mod(var)E1275 Mod(var)E1275 http://flybase.org/reports/FBgn0062573 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1275, Mod(var)E1275" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0032117 FucTB FucTB http://flybase.org/reports/FBgn0032117 protein_coding_gene alpha-(1->3)-fucosyltransferase activity ; GO:0046920 | inferred from biological aspect of ancestor with PANTHER:PTN000231531 "protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR001503, InterPro:IPR017176" Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000231531 "CT14430, CG4435, FucTB" "IPR001503:Glycosyl transferase family 10, IPR017176:Alpha-(1, 3)-fucosyltransferase, metazoan, IPR031481:Fucosyltransferase, N-terminal" CG4435 11-Aug-17 DroID_v2017_08 "Drer\ft1, Drer\fut9b, Drer\fut10, Drer\zgc:103510, Drer\zgc:136963, Drer\zgc:112433, Drer\si:ch1073-440p11.2, Drer\zgc:173737, Drer\ft2, Drer\fut9d, Drer\zgc:165582, Drer\zgc:165519, Drer\fut9a, Drer\fut11, Drer\fut7" - Cele\fut-1 "Xtro\fut3, Xtro\fut4, Xtro\fut11, Xtro\fut6, Xtro\fut10, Xtro\fut9" "Mmus\Fut7, Mmus\Fut11, Mmus\Fut10, Mmus\Fut9, Mmus\Fut4" "Hsap\FUT3, Hsap\FUT10, Hsap\FUT9, Hsap\FUT4, Hsap\FUT7, Hsap\FUT11, Hsap\FUT6, Hsap\FUT5" viable FBgn0025150 ms(2)A6 ms(2)A6 http://flybase.org/reports/FBgn0025150 - gene - - - ms(2)A6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0264509 CR43908 - http://flybase.org/reports/FBgn0264509 non_protein_coding_gene - - - CR43908 - CR43908 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266315 CR44980 - http://flybase.org/reports/FBgn0266315 non_protein_coding_gene - - - CR44980 - CR44980 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085607 CG41311 - http://flybase.org/reports/FBgn0085607 protein_coding_gene - - - CG41311 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261085 Syt12 Synaptotagmin 12 http://flybase.org/reports/FBgn0261085 protein_coding_gene clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium-dependent phospholipid binding ; GO:0005544 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 regulation of neurotransmitter secretion ; GO:0046928 | inferred from electronic annotation with InterPro:IPR030537 long-term synaptic potentiation ; GO:0060291 | inferred from electronic annotation with InterPro:IPR030537 calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 regulation of calcium ion-dependent exocytosis ; GO:0017158 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 integral component of membrane ; GO:0016021 | inferred from sequence model "Syt12, Syt 12, dsyt12, syt12, CG10617" "IPR000008:C2 domain, IPR030537:Synaptotagmin-12" CG10617 11-Aug-17 DroID_v2017_08 "Drer\LOC570938, Drer\syt12" - "Cele\snt-4, Cele\snt-7" - Mmus\Syt12 "Hsap\SYT3, Hsap\SYT12, Hsap\SYT10, Hsap\SYT6, Hsap\SYT9" FBgn0044029 NOF\ORF NOF element ORF http://flybase.org/reports/FBgn0044029 transposable_element_gene - - - NOF\ORF - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051419 CG31419 - http://flybase.org/reports/FBgn0051419 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG5329, CG31419" - CG31419 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034649 PIG-M Phosphatidylinositol glycan anchor biosynthesis class M http://flybase.org/reports/FBgn0034649 protein_coding_gene "transferase activity, transferring hexosyl groups ; GO:0016758 | inferred from electronic annotation with InterPro:IPR007704" GPI anchor biosynthetic process ; GO:0006506 | inferred from electronic annotation with InterPro:IPR007704 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007704 "CG9865, Dromel_CG9865_FBtr0071680_cx9c_morf, PIG-M" "IPR007704:Mannosyltransferase, DXD" CG9865 11-Aug-17 DroID_v2017_08 Drer\pigm Scer\GPI14 Cele\B0491.1 Xtro\pigm Mmus\Pigm Hsap\PIGM FBgn0015725 Eig82F Ecdysone induced gene at 82F http://flybase.org/reports/FBgn0015725 - gene - - - Eig82F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085499 CG40600 - http://flybase.org/reports/FBgn0085499 protein_coding_gene - - - CG40600 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040763 CG18336 - http://flybase.org/reports/FBgn0040763 protein_coding_gene - - - "CG13212, CG18336" IPR018902:Uncharacterised protein family UPF0573/UPF0605 CG18336 11-Aug-17 DroID_v2017_08 Drer\fam166b - "Cele\T09D3.8, Cele\F49C5.10" - "Mmus\Fam166b, Mmus\Fam166a" "Hsap\FAM166B, Hsap\FAM166A" viable FBgn0038306 Art3 Arginine methyltransferase 3 http://flybase.org/reports/FBgn0038306 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR025799 peptidyl-arginine methylation ; GO:0018216 | inferred from sequence or structural similarity with RGD:620413 - "DART3, CG6563, Art3" "IPR013087:Zinc finger C2H2-type, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR025799:Protein arginine N-methyltransferase" CG6563 11-Aug-17 DroID_v2017_08 "Drer\LOC556054, Drer\prmt8b, Drer\prmt1, Drer\prmt6, Drer\prmt3" "Scer\HMT1, Scer\CRG1" Cele\C37A2.6 "Xtro\prmt3, Xtro\prmt8, Xtro\prmt6, Xtro\prmt1" "Mmus\Prmt2, Mmus\Ndufaf5, Mmus\Prmt3, Mmus\Prmt8, Mmus\Prmt6, Mmus\Prmt1" "Hsap\PRMT2, Hsap\ETFBKMT, Hsap\NDUFAF5, Hsap\PRMT3, Hsap\PRMT1, Hsap\PRMT6, Hsap\PRMT8" "viable,fertile" FBgn0019852 anon-XII anon-XII http://flybase.org/reports/FBgn0019852 - gene - - - "XII, anon-XII" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024941 RSG7 Regulator of G-protein signaling 7 http://flybase.org/reports/FBgn0024941 "FBtr0074350, FBpp0074124" protein_coding_gene signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR015898 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR000591 regulation of G-protein coupled receptor protein signaling pathway ; GO:0008277 | inferred from sequence or structural similarity with WB:WBGene00001179 heterotrimeric G-protein complex ; GO:0005834 | inferred from electronic annotation with InterPro:IPR015898 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 "RGS7, dRGS7, CG9108, RSG7" "IPR015898:G-protein gamma-like domain, IPR000591:DEP domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016137:RGS domain, IPR024066:RGS, subdomain 1, IPR034483:Regulator of G-protein signalling Egl-10" CG9108 11-Aug-17 DroID_v2017_08 "Drer\rgs19, Drer\rgs1, Drer\rgs5b, Drer\rgs12b, Drer\rgs4, Drer\rgs13, Drer\rgs8, Drer\si:ch211-152p11.4, Drer\si:ch211-196h16.12, Drer\rgs7b, Drer\rgs18, Drer\rgs12a, Drer\rgs3a, Drer\si:ch211-117l17.5, Drer\rgs14b, Drer\rgs9b, Drer\axin1, Drer\rgs11, Drer\rgs17, Drer\rgs7a, Drer\rgs6, Drer\rgs5a, Drer\si:ch211-117l17.6, Drer\rgs14a, Drer\axin2, Drer\rgs2, Drer\rgs16, Drer\grid2ipb" "Scer\SST2, Scer\RGS2" "Cele\eat-16, Cele\rgs-6, Cele\rgs-4, Cele\egl-10" "Xtro\rgs10, Xtro\rgs6, Xtro\rgs16, Xtro\rgs1, Xtro\rgs17, Xtro\xarp, Xtro\rgs20, Xtro\rgs2, Xtro\axin1, Xtro\rgs19, Xtro\rgs5, Xtro\cep112, Xtro\rgs4, Xtro\rgs3, Xtro\rgs18" "Mmus\Rgs3, Mmus\Rgs9, Mmus\Rgs14, Mmus\Rgs2, Mmus\Axin1, Mmus\Rgs11, Mmus\Rgs8, Mmus\Rgs12, Mmus\Rgs5, Mmus\Rgs1, Mmus\Rgs20, Mmus\Rgsl1, Mmus\Rgs17, Mmus\Rgs4, Mmus\Rgs16, Mmus\Rgs7, Mmus\Rgs18, Mmus\Rgs13, Mmus\Rgs10, Mmus\Axin2, Mmus\Rgs19, Mmus\Rgs6" "Hsap\AXIN2, Hsap\RGS17, Hsap\RGS12, Hsap\RGS14, Hsap\RGS20, Hsap\RGS6, Hsap\RGS3, Hsap\RGS21, Hsap\RGS11, Hsap\RGS2, Hsap\RGS19, Hsap\RGS18, Hsap\RGS16, Hsap\RGS7, Hsap\RGS13, Hsap\RGS10, Hsap\RGS8, Hsap\RGS5, Hsap\AXIN1, Hsap\RGS4, Hsap\RGS9, Hsap\RGS1, Hsap\RGSL1" "partially lethal - majority die,some die during pupal stage" DRSC20274 EK 0.088714279 0.479881958 -0.166699895 1.755589105 -1.513719552 -0.695144892 FBgn0261686 CG42733 - http://flybase.org/reports/FBgn0261686 protein_coding_gene - - - "CG12901, Tes85-2, CG42733" - CG42733 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052529 Hers Histone gene-specific Epigenetic Repressor in late S phase http://flybase.org/reports/FBgn0052529 protein_coding_gene transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 chromatin silencing ; GO:0006342 | inferred from mutant phenotype heterochromatin assembly ; GO:0031507 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 chromatin remodeling ; GO:0006338 | inferred from mutant phenotype inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype chromatin ; GO:0000785 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 chromatin silencing complex ; GO:0005677 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 "CG15619, CG11936, CG32529, Hers, HERS" "IPR001025:Bromo adjacent homology (BAH) domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG32529 11-Aug-17 DroID_v2017_08 "Drer\bahd1, Drer\LOC100331694" - - Xtro\bahd1 "Mmus\Tnrc18, Mmus\Bahd1" Hsap\BAHD1 "suppressor of variegation,viable,fertile" eye DRSC19429 K 1.048545568 1.163515932 -0.436466355 0.4944286 1.852608506 1.954492388 FBgn0032749 Phlpp PH domain leucine-rich repeat protein phosphatase http://flybase.org/reports/FBgn0032749 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from direct assay inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8INB9 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement regulation of apoptotic process ; GO:0042981 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from direct assay inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CT29458, PP2C, Phlpp, CG10493, dPHLPP" "IPR001611:Leucine-rich repeat, IPR001932:PPM-type phosphatase domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG10493 11-Aug-17 DroID_v2017_08 "Drer\tlr2, Drer\phlpp2, Drer\tlr21, Drer\phlpp1, Drer\tlr19, Drer\dnaaf1, Drer\shoc2" Scer\CYR1 "Cele\soc-2, Cele\F43C1.1" Xtro\phlpp2 "Mmus\Tlr2, Mmus\Dnaaf1, Mmus\Shoc2, Mmus\Phlpp2, Mmus\Phlpp1" "Hsap\DNAAF1, Hsap\TLR2, Hsap\PHLPP2, Hsap\PHLPP1, Hsap\SHOC2" viable FBgn0067346 l(3)95Ef lethal (3) 95Ef http://flybase.org/reports/FBgn0067346 gene - - - l(3)95Ef - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262386 mir-306 mir-306 stem loop http://flybase.org/reports/FBgn0262386 miRNA_gene - - - "mir-306, miR-306, dme-mir-306, 306, MIR-306, CR42914, CR33609, MiR-306, CR33610, mir-306*, miR-306S, mir-306S, miR-306-star, dme-miR-306, dme-miR-306-5p, miR-306/79/9b" - CR42914 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "eye,wing,spermatocyte cyst" FBgn0015471 l(2)45ABa lethal (2) 45ABa http://flybase.org/reports/FBgn0015471 - gene - - - l(2)45ABa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0259256 C684 - http://flybase.org/reports/FBgn0259256 gene - - - C684 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin" FBgn0050121 CR30121 - http://flybase.org/reports/FBgn0050121 non_protein_coding_gene - - - "CG30121, CR30121, BcDNA:GH12850" - CR30121 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036104 CG6418 - http://flybase.org/reports/FBgn0036104 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 helicase activity ; GO:0004386 | inferred from sequence or structural similarity RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "DmRH27, cg6418, CG6418" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG6418 11-Aug-17 DroID_v2017_08 "Drer\ddx42, Drer\ddx46" "Scer\PRP5, Scer\DBP2" "Cele\C46F11.4, Cele\F53H1.1" "Xtro\ddx46, Xtro\ddx42" "Mmus\Ddx46, Mmus\Ddx42" "Hsap\DDX42, Hsap\DDX46" viable FBgn0005266 l(3)SG86 lethal (3) SG86 http://flybase.org/reports/FBgn0005266 - gene - - - l(3)SG86 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,heat sensitive,some die during larval stage" FBgn0040207 kat80 katanin 80 http://flybase.org/reports/FBgn0040207 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR026962 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype microtubule severing ; GO:0051013 | inferred from sequence or structural similarity with NCBI_gi:3005599 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity katanin complex ; GO:0008352 | inferred from sequence or structural similarity with NCBI_gi:3005599 cytosol ; GO:0005829 | inferred from direct assay "CG9910, CG13956, kat80, Kat80, Katanin80" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like, IPR026962:Katanin p80 subunit B1, IPR028021:Katanin p80 subunit, C-terminal" CG13956 11-Aug-17 DroID_v2017_08 "Drer\katnbl1, Drer\katnb1, Drer\wdr90" Scer\PRP4 "Cele\F47G4.4, Cele\F47G4.5" "Xtro\katnb1, Xtro\wdr90, Xtro\katnbl1" "Mmus\Wdr90, Mmus\Katnbl1, Mmus\Katnb1" "Hsap\KATNBL1, Hsap\KATNB1" "viable,body color defective,planar polarity defective" "mesothoracic tergum,dorsal appendage" FBgn0015336 CG15865 - http://flybase.org/reports/FBgn0015336 - protein_coding_gene - - - "anon-15Ab, CG15865" IPR024810:Mab-21 domain CG15865 11-Aug-17 DroID_v2017_08 "Drer\mb21d2, Drer\mab21l2, Drer\si:dkey-11f12.2, Drer\mab21l3, Drer\LOC556707, Drer\mab21l1" - - "Xtro\mb21d2, Xtro\mab21l1" "Mmus\Mab21l2, Mmus\Mb21d2, Mmus\Mab21l3, Mmus\Mab21l1, Mmus\2310007B03Rik, Mmus\Tmem102" "Hsap\MB21D2, Hsap\MAB21L3, Hsap\TMEM102, Hsap\MAB21L2, Hsap\C2orf54, Hsap\MAB21L1" viable DRSC19733 K -0.292763599 0.37776838 0.125075029 0.636934779 1.833469416 -0.679733593 FBgn0263039 CR43334 - http://flybase.org/reports/FBgn0263039 non_protein_coding_gene - - - "CR43334, pri-bantam" - CR43334 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0065326 l(2)SH1897 lethal (2) SH1897 http://flybase.org/reports/FBgn0065326 gene - - - l(2)SH1897 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003367 sf safranin http://flybase.org/reports/FBgn0003367 FBgn0000461 gene - - - "dki, sf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" "pigment cell,Malpighian tubule" FBgn0259280 C517 - http://flybase.org/reports/FBgn0259280 gene - - - C517 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta,ectopic" FBgn0002004 l(2)36Bc lethal (2) 36Bc http://flybase.org/reports/FBgn0002004 - gene - - - "l(2L)HT-10, l(2)HT-10, l(2)36Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265809 CR44598 - http://flybase.org/reports/FBgn0265809 non_protein_coding_gene - - - "lincRNA.119, CR44598" - CR44598 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265717 CR44524 - http://flybase.org/reports/FBgn0265717 non_protein_coding_gene - - - "lincRNA.976, CR44524" - CR44524 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002332 l(3)87Ae lethal (3) 87Ae http://flybase.org/reports/FBgn0002332 - gene - - - "ck12, l(3)ck12, l(3)87Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" Malpighian tubule FBgn0030223 CG2111 - http://flybase.org/reports/FBgn0030223 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 phagocytosis ; GO:0006909 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "pepCG2111, CG2111" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG2111 11-Aug-17 DroID_v2017_08 "Drer\anpepb, Drer\si:ch211-106j24.1, Drer\si:ch211-149p5.1, Drer\erap2, Drer\anpepa, Drer\npepps, Drer\erap1b, Drer\erap1a, Drer\enpep, Drer\si:ch211-198g19.1, Drer\lnpep, Drer\si:ch211-276a23.5" "Scer\AAP1, Scer\APE2, Scer\TMA108" "Cele\T16G12.1, Cele\Y53F4B.20, Cele\F49B2.6, Cele\T07F10.1, Cele\T12E12.6, Cele\Y67D8C.9, Cele\pam-1, Cele\VB0395L.1, Cele\R03G8.4, Cele\R03G8.6, Cele\AC3.5, Cele\mnp-1, Cele\Y42A5A.1" "Xtro\enpep, Xtro\lnpep, Xtro\erap1, Xtro\lvrn, Xtro\npepps, Xtro\anpep" "Mmus\Enpep, Mmus\Erap1, Mmus\Npepps, Mmus\Lvrn, Mmus\Anpep, Mmus\Trhde, Mmus\Lnpep" "Hsap\ANPEP, Hsap\NPEPPS, Hsap\LVRN, Hsap\ERAP2, Hsap\TRHDE, Hsap\LNPEP, Hsap\ENPEP, Hsap\ERAP1" "viable,fertile,visible" "chaeta,supernumerary" FBgn0038918 CG6690 - http://flybase.org/reports/FBgn0038918 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR017905 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model CG6690 "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017905:ERV/ALR sulfhydryl oxidase domain" CG6690 11-Aug-17 DroID_v2017_08 "Drer\qsox2, Drer\qsox1" - "Cele\T10H10.2, Cele\F47B7.2, Cele\F35G2.1" "Xtro\qsox2, Xtro\qsox1" "Mmus\Qsox2, Mmus\Qsox1" "Hsap\QSOX1, Hsap\QSOX2" viable FBgn0040820 CG14146 - http://flybase.org/reports/FBgn0040820 protein_coding_gene - - - CG14146 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029041 l(2)F2 lethal (2) F2 http://flybase.org/reports/FBgn0029041 gene - - - "F2, l(2)F2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000706 fltL flight defective L http://flybase.org/reports/FBgn0000706 - gene - - - fltL - - 11-Aug-17 DroID_v2017_08 - - - - - - flightless FBgn0051710 CG31710 - http://flybase.org/reports/FBgn0051710 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31710, EP2160" - CG31710 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0084120 tgl tangled http://flybase.org/reports/FBgn0084120 gene - - - tgl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262398 mir-124 mir-124 stem loop http://flybase.org/reports/FBgn0262398 miRNA_gene - gene silencing by miRNA ; GO:0035195 | inferred from direct assay neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of synaptic transmission ; GO:0050805 | inferred from mutant phenotype - "mir-124, miR-124, dme-mir-124, MIR-124, CR42937, Mir-124, CR33573, mir-124b, miR-124a, dme-miR-124, mir-124a" - CR42937 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , larval stage | first instar " FBgn0036835 CG14075 - http://flybase.org/reports/FBgn0036835 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG14075 - CG14075 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004005 wdl wavoid-like http://flybase.org/reports/FBgn0004005 - gene - - - wdl - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female semi-sterile,lethal,maternal effect" "wing,wing vein L5" FBgn0034822 RpL37b Ribosomal protein L37b http://flybase.org/reports/FBgn0034822 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR018267 structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080456" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR011332, InterPro:IPR018267 translation ; GO:0006412 | inferred from sequence model cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR018267 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "CG9873, RpL37b, Rpl37b" "IPR018267:Ribosomal protein L37e, conserved site, IPR011331:Ribosomal protein L37ae/L37e, IPR011332:Zinc-binding ribosomal protein, IPR001569:Ribosomal protein L37e" CG9873 11-Aug-17 DroID_v2017_08 Drer\rpl37 "Scer\RPL37A, Scer\RPL37B" "Cele\rpl-37, Cele\W01D2.1" Xtro\rpl37 "Mmus\Rpl37rt, Mmus\Rpl37" Hsap\RPL37 "viable,visible" trichogen cell FBgn0260249 GSd495 - http://flybase.org/reports/FBgn0260249 gene - - - GSd495 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001528 l(1)11Ed lethal (1) 11Ed http://flybase.org/reports/FBgn0001528 - gene - - - l(1)11Ed - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0082986 snoRNA:Psi28S-2562 snoRNA:Psi28S-2562 http://flybase.org/reports/FBgn0082986 snoRNA_gene - - - "snoRNA:Psi28S-2562, psi28s-2562, Psi 28S-2562, CR34616, chr3R:16648632..16648732" - CR34616 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034440 CG10073 - http://flybase.org/reports/FBgn0034440 protein_coding_gene - - - CG10073 IPR007484:Peptidase M28 CG10073 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\PFF1, Scer\VPS70, Scer\APE3, Scer\YDR415C" "Cele\B0495.7, Cele\C44B7.11" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0051388 CG31388 - http://flybase.org/reports/FBgn0051388 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG5135, CG17722, BcDNA:GH10523, CG31388" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG31388 11-Aug-17 DroID_v2017_08 "Drer\znf1043, Drer\znf644a, Drer\zgc:173624, Drer\znf408, Drer\LOC101883642, Drer\LOC100537066, Drer\znf687a, Drer\LOC100149007, Drer\znf990, Drer\zgc:174696, Drer\znf1059, Drer\zbtb41, Drer\si:dkey-217d24.6, Drer\LOC100536649, Drer\znf1041, Drer\LOC103910931, Drer\si:ch211-194b1.1, Drer\LOC103910994, Drer\zgc:173705, Drer\znf569l, Drer\znf1073, Drer\zgc:174704, Drer\si:ch211-226o13.2, Drer\gb:am422109, Drer\si:ch211-162i8.2, Drer\LOC100538201, Drer\znf687b, Drer\znf407, Drer\zbtb17, Drer\zgc:173716, Drer\si:ch211-255f4.1, Drer\LOC100537431, Drer\mynn, Drer\LOC101882787, Drer\LOC108183429, Drer\LOC100535113, Drer\LOC100537572, Drer\LOC100534892, Drer\zbtb16b, Drer\si:dkeyp-104f11.6, Drer\prdm4, Drer\zgc:173714, Drer\znf1171, Drer\znf1147, Drer\znf1181, Drer\zgc:174703, Drer\zgc:174314, Drer\znf1053, Drer\LOC101885678, Drer\LOC100333857, Drer\znf1070, Drer\LOC108182424, Drer\LOC100333583, Drer\znf1177, Drer\si:dkeyp-35e5.9, Drer\LOC101885193, Drer\znf644b, Drer\znf507, Drer\znf995, Drer\LOC101882721, Drer\zbtb39, Drer\si:dkeyp-53d3.5, Drer\zgc:162948, Drer\si:dkeyp-35e5.10, Drer\si:dkey-20i20.2, Drer\znf1069, Drer\si:dkeyp-84f3.9, Drer\LOC100536900, Drer\si:dkey-30f3.2, Drer\znf1167, Drer\si:dkey-7i4.5, Drer\si:dkey-237m9.1, Drer\zgc:173713, Drer\LOC100537352, Drer\znf1077, Drer\znf1079, Drer\prdm2b, Drer\znf1068, Drer\znf1040, Drer\hnrnpa0l, Drer\si:ch211-223a21.4, Drer\zgc:113135, Drer\LOC100536312, Drer\zgc:174315, Drer\LOC100537450, Drer\LOC100537891, Drer\znf1173, Drer\si:dkey-1b17.5, Drer\znf1072, Drer\znf319, Drer\LOC100149645, Drer\znf592, Drer\si:dkey-262g12.7, Drer\znf1159, Drer\LOC108179202, Drer\prdm2a, Drer\LOC108184006, Drer\si:ch211-212k5.4, Drer\LOC101882607, Drer\si:ch211-255f4.3, Drer\LOC108183430, Drer\znf1078, Drer\LOC100536110, Drer\LOC100534765, Drer\LOC100150619, Drer\LOC569391, Drer\si:ch73-266f23.3, Drer\LOC100329723, Drer\LOC100332458" - "Cele\Y55F3AM.14, Cele\F58G1.2, Cele\eor-1, Cele\C27A12.2, Cele\M03D4.4, Cele\blmp-1, Cele\zfp-2" "Xtro\znf639, Xtro\znf91" "Mmus\4930522L14Rik, Mmus\Zfp866, Mmus\Zfp960, Mmus\Zfp872, Mmus\Prdm4, Mmus\Zbtb41, Mmus\Zfp984, Mmus\Zfp947, Mmus\Zfp445, Mmus\Rex2, Mmus\Zfp120, Mmus\Zfp991, Mmus\Mynn, Mmus\Zfp992, Mmus\Zfp995, Mmus\Zbtb17, Mmus\Zfp287, Mmus\Zfp697, Mmus\Zfp429, Mmus\Zfp768, Mmus\Zfp784, Mmus\Gzf1, Mmus\Zfp563, Mmus\Zfp646, Mmus\Zfp980, Mmus\Zfp985, Mmus\Zfp408, Mmus\Zfp932, Mmus\Zfp398, Mmus\Zfp592, Mmus\Zfp358, Mmus\Zfp426, Mmus\Zfp94, Mmus\Zfp109, Mmus\Zfp534, Mmus\AU041133, Mmus\Zfp870, Mmus\Zfp97, Mmus\Zfp93, Mmus\Rsl1, Mmus\Zfp57, Mmus\Zfp982, Mmus\Zfp407, Mmus\Gm20939, Mmus\Zfp777, Mmus\Zfp868, Mmus\Zfp944, Mmus\Zfp472, Mmus\Zfp687, Mmus\Zfp507, Mmus\Zfp626, Mmus\Zfp644, Mmus\Zfp943, Mmus\Zfp61, Mmus\Zfp114, Mmus\Zfp979, Mmus\Zfp758, Mmus\Gm4767, Mmus\Zfp597, Mmus\Zfp786, Mmus\Zfp108, Mmus\Prdm2, Mmus\Zbtb39, Mmus\Zfp462, Mmus\Zfp867, Mmus\Zfp946, Mmus\Zfp981, Mmus\Zfp942, Mmus\Gm10778, Mmus\Zkscan7, Mmus\Zfp820, Mmus\Zfp951, Mmus\Zfp871, Mmus\Zfp319, Mmus\Zfp746, Mmus\Zfp467, Mmus\Zfp987" "Hsap\ZNF445, Hsap\ZNF687, Hsap\ZNF527, Hsap\ZNF777, Hsap\ZNF697, Hsap\ZBTB17, Hsap\ZNF507, Hsap\ZNF467, Hsap\ZNF417, Hsap\ZNF426, Hsap\ZNF333, Hsap\ZNF462, Hsap\ZNF281, Hsap\ZNF547, Hsap\ZNF133, Hsap\ZNF806, Hsap\ZNF852, Hsap\ZNF784, Hsap\ZNF644, Hsap\ZNF768, Hsap\ZNF670, Hsap\ZNF230, Hsap\ZFP57, Hsap\ZNF234, Hsap\ZNF597, Hsap\ZNF786, Hsap\ZNF34, Hsap\ZNF407, Hsap\ZNF592, Hsap\MYNN, Hsap\ZNF287, Hsap\ZNF774, Hsap\ZNF746, Hsap\ZNF776, Hsap\ZKSCAN7, Hsap\PRDM2, Hsap\ZNF625, Hsap\ZNF416, Hsap\ZNF214, Hsap\ZNF582, Hsap\ZNF780A, Hsap\ZNF319, Hsap\ZNF251, Hsap\ZBTB41, Hsap\ZNF398, Hsap\ZNF530, Hsap\ZNF17, Hsap\ZNF566, Hsap\GZF1, Hsap\ZNF707, Hsap\PRDM4, Hsap\ZNF285, Hsap\ZBTB39, Hsap\ZNF408, Hsap\ZNF222, Hsap\ZNF136, Hsap\ZNF587, Hsap\ZNF223, Hsap\ZNF646, Hsap\ZNF155, Hsap\ZNF8" "viable,fertile" FBgn0015955 l(1)5ABa lethal (1) 5ABa http://flybase.org/reports/FBgn0015955 - gene - - - l(1)5ABa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044508 snoRNA:M snoRNA:M http://flybase.org/reports/FBgn0044508 snoRNA_gene - - - "CR32807, snoRNA:M" - CR32807 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051856 CG31856 - http://flybase.org/reports/FBgn0051856 protein_coding_gene - - - "BcDNA:SD21618, CG31856" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal" mesothoracic tergum FBgn0000434 der deranged http://flybase.org/reports/FBgn0000434 - gene - - - der - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile,reduced,visible,recessive,female semi-sterile" "microchaeta & adult thorax,wing,macrochaeta & adult thorax" FBgn0032889 CG9331 - http://flybase.org/reports/FBgn0032889 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR006139 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" extracellular region ; GO:0005576 | inferred from direct assay CG9331 "IPR006139:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040:NAD(P)-binding domain, IPR029753:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site" CG9331 11-Aug-17 DroID_v2017_08 "Drer\zgc:136493, Drer\grhprb, Drer\grhpra" "Scer\SER33, Scer\SER3, Scer\FDH1, Scer\YGL185C, Scer\YPL113C, Scer\GOR1" - "Xtro\grhpr.2, Xtro\grhpr.1" Mmus\Grhpr Hsap\GRHPR "viable,fertile" FBgn0023217 E(lz)53 E(lz)53 http://flybase.org/reports/FBgn0023217 - gene - - - E(lz)53 - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0065256 l(2)SH2109 lethal (2) SH2109 http://flybase.org/reports/FBgn0065256 gene - - - "l(2)SH2109, l(2)SH2 2109" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261819 CG42761 - http://flybase.org/reports/FBgn0261819 protein_coding_gene - - - CG42761 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004966 larv larvaphile http://flybase.org/reports/FBgn0004966 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Lar, larv, lar" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect" FBgn0001451 l(1)7De lethal (1) 7De http://flybase.org/reports/FBgn0001451 - gene - - - l(1)7De - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036471 CG13460 - http://flybase.org/reports/FBgn0036471 protein_coding_gene - - - CG13460 - CG13460 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005306 ms(1)244 male sterile (1) 244 http://flybase.org/reports/FBgn0005306 - gene - - - ms(1)244 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,meiotic cell cycle defective,behavior defective" "meiotic cell cycle | male,meiotic anaphase I & nuclear chromosome,meiotic cell cycle & spindle | male,spermatocyte & nucleus,spermatocyte & centriole,spermatid" FBgn0266987 CR45438 - http://flybase.org/reports/FBgn0266987 non_protein_coding_gene - - - CR45438 - CR45438 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262547 CG43101 - http://flybase.org/reports/FBgn0262547 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43101 - CG43101 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035187 Trh Tryptophan hydroxylase http://flybase.org/reports/FBgn0035187 protein_coding_gene "amino acid binding ; GO:0016597 | inferred from electronic annotation with InterPro:IPR002912 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 phenylalanine 4-monooxygenase activity ; GO:0004505 | inferred from direct assay tryptophan 5-monooxygenase activity ; GO:0004510 | inferred from direct assay" "aromatic amino acid family metabolic process ; GO:0009072 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR005963, InterPro:IPR018301, InterPro:IPR019773, InterPro:IPR019774 regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype serotonin biosynthetic process ; GO:0042427 | inferred from direct assay" - "Trh, DTRH, CG9122, CT9937, TRH, TRHn, dTrh, DTRHn" "IPR018301:Aromatic amino acid hydroxylase, iron/copper binding site, IPR001273:Aromatic amino acid hydroxylase, IPR005963:Tryptophan 5-monooxygenase, IPR019773:Tyrosine 3-monooxygenase-like, IPR019774:Aromatic amino acid hydroxylase, C-terminal, IPR002912:ACT domain" CG9122 11-Aug-17 DroID_v2017_08 "Drer\tph2, Drer\pah, Drer\th2, Drer\th, Drer\tph1a, Drer\tph1b" - "Cele\cat-2, Cele\tph-1, Cele\pah-1" "Xtro\tph1, Xtro\pah, Xtro\th" "Mmus\Th, Mmus\Tph2, Mmus\Tph1, Mmus\Pah" "Hsap\TPH1, Hsap\TPH2, Hsap\TH, Hsap\PAH" "behavior defective,male,viable,fertile,feeding behavior defective,smell perception defective,neuroanatomy defective,partially lethal - majority die,some die during larval stage" FBgn0065327 l(2)SH1895 lethal (2) SH1895 http://flybase.org/reports/FBgn0065327 gene - - - "l(2)SH1895, l(2)SH2 1895" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262151 esi-4 endogenous siRNA 4 http://flybase.org/reports/FBgn0262151 gene - - - "esi-4, esiRNA-sl-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065834 l(2)SH0342 lethal (2) SH0342 http://flybase.org/reports/FBgn0065834 gene - - - "l(2)SH0342, l(2)SH2 0342" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028850 CG15260 - http://flybase.org/reports/FBgn0028850 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BG:DS07851.8, CG15260" - CG15260 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell FBgn0267711 CR46044 - http://flybase.org/reports/FBgn0267711 non_protein_coding_gene - - - CR46044 - CR46044 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267056 CR45500 - http://flybase.org/reports/FBgn0267056 non_protein_coding_gene - - - CR45500 - CR45500 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034186 CG8950 - http://flybase.org/reports/FBgn0034186 protein_coding_gene "transcription factor activity, core RNA polymerase III binding ; GO:0000995 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000555283" transcription from RNA polymerase III promoter ; GO:0006383 | inferred from biological aspect of ancestor with PANTHER:PTN000555283 transcription factor TFIIIC complex ; GO:0000127 | inferred from biological aspect of ancestor with PANTHER:PTN000555283 CG8950 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG8950 11-Aug-17 DroID_v2017_08 "Drer\lig4, Drer\gtf3c3" "Scer\TFC4, Scer\DNL4" Cele\tftc-3 "Xtro\gtf3c3, Xtro\lig4" "Mmus\Lig4, Mmus\Gtf3c3" "Hsap\LIG4, Hsap\GTF3C3" viable FBgn0022351 anon-25Dc anon-25Dc http://flybase.org/reports/FBgn0022351 - gene - - - "e4, anon-25Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003000 On Open http://flybase.org/reports/FBgn0003000 - gene - - - On - - 11-Aug-17 DroID_v2017_08 - - - - - - viable wing FBgn0267953 CR46233 - http://flybase.org/reports/FBgn0267953 non_protein_coding_gene - - - "CR46233, lincRNA.861" - CR46233 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024502 Aco Accordion http://flybase.org/reports/FBgn0024502 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available Aco - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084704 836 836 http://flybase.org/reports/FBgn0084704 gene - - - 836 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034692 CG13502 - http://flybase.org/reports/FBgn0034692 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13502 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG13502 11-Aug-17 DroID_v2017_08 "Drer\ifit16, Drer\kdm6al, Drer\tomm34, Drer\ttc25, Drer\kdm6a, Drer\fkbpl, Drer\dyx1c1, Drer\tmtc3, Drer\ifit14, Drer\ogt.1, Drer\ifit15, Drer\ifit9, Drer\kdm6ba, Drer\ifit8, Drer\spag1a, Drer\bbs4, Drer\ogt.2, Drer\spag1b, Drer\ttc6" "Scer\SWA2, Scer\TAH1, Scer\CYC8" - "Xtro\bbs4, Xtro\kdm6a, Xtro\tmtc3, Xtro\ttc25, Xtro\kdm6b, Xtro\ifit5, Xtro\ttc16, Xtro\dyx1c1, Xtro\spag1, Xtro\ogt" "Mmus\Lonrf3, Mmus\Dyx1c1, Mmus\Ifit1bl1, Mmus\Uty, Mmus\Ifit3, Mmus\Ogt, Mmus\Ttc25, Mmus\Bbs4, Mmus\Ifit1bl2, Mmus\Tomm34, Mmus\Ifit3b, Mmus\Ifit2, Mmus\Ttc16, Mmus\Tmtc3, Mmus\Tmtc1, Mmus\Ttc24, Mmus\Kdm6a, Mmus\Spag1, Mmus\Ifit1, Mmus\Fkbpl, Mmus\Kdm6b" "Hsap\UTY, Hsap\IFIT3, Hsap\TTC24, Hsap\TTC32, Hsap\TTC6, Hsap\TMTC3, Hsap\TTC25, Hsap\TTC16, Hsap\DYX1C1, Hsap\IFIT1, Hsap\KDM6B, Hsap\IFIT2, Hsap\FKBPL, Hsap\BBS4, Hsap\IFIT5, Hsap\TOMM34, Hsap\SPAG1, Hsap\LONRF3, Hsap\OGT, Hsap\IFIT1B, Hsap\LONRF2, Hsap\TMTC1, Hsap\KDM6A" viable FBgn0000493 drb dark red brown http://flybase.org/reports/FBgn0000493 - gene - - - drb - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,cold sensitive" "pigment cell,cold sensitive" FBgn0030813 CG4949 - http://flybase.org/reports/FBgn0030813 protein_coding_gene - - - CG4949 - CG4949 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0086205 S(ls)7 - http://flybase.org/reports/FBgn0086205 gene - - - S(ls)7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085245 CG34216 - http://flybase.org/reports/FBgn0085245 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34216 IPR031958:Protein of unknown function DUF4778 CG34216 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039916 Ekar Eye-enriched kainate receptor http://flybase.org/reports/FBgn0039916 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity with HGNC:4579 "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 synaptic transmission, glutamatergic ; GO:0035249 | inferred from genetic interaction with Ih regulation of synaptic activity ; GO:0060025 | inferred from sequence or structural similarity with GluRIIA regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from mutant phenotype inferred from genetic interaction with Ih cellular response to light intensity ; GO:0071484 | inferred from mutant phenotype optomotor response ; GO:0071632 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with GluRIIA "CT36399, DmelCG9935, CG9935, Ekar, ekar" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG9935 11-Aug-17 DroID_v2017_08 "Drer\grik5, Drer\LOC100537813, Drer\LOC100334689, Drer\grik2, Drer\grid1b, Drer\grik1a, Drer\grik1b, Drer\grid1a, Drer\grid2, Drer\grik4, Drer\LOC100331381" - "Cele\W02A2.5, Cele\F59E12.8, Cele\glr-3, Cele\glr-4, Cele\glr-6, Cele\glr-5, Cele\C08B6.5" "Xtro\grik1, Xtro\grik4" "Mmus\Grik1, Mmus\Grik4, Mmus\Grid1, Mmus\Grik5, Mmus\Grik3, Mmus\Grik2, Mmus\Grid2" "Hsap\GRID2, Hsap\GRIK1, Hsap\GRIK3, Hsap\GRID1, Hsap\GRIK5, Hsap\GRIK4, Hsap\GRIK2" viable DRSC24931 K -0.052055398 -0.620377827 -0.309879735 0.381367144 0.369896691 2.03668539 FBgn0263647 CG43638 - http://flybase.org/reports/FBgn0263647 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43638 - CG43638 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026388 Or46a Odorant receptor 46a http://flybase.org/reports/FBgn0026388 "FBgn0026387, FBgn0053478" protein_coding_gene olfactory receptor activity ; GO:0004984 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from mutant phenotype olfactory receptor activity ; GO:0004984 | inferred from sequence or structural similarity with Or85e sensory perception of smell ; GO:0007608 | inferred from sequence or structural similarity with Or85e detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from sequence model dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "Or46aB, Or46aA, Or46b, dor19, 46b, 46a, DOR20, DOR19, CG17849, AN9, 46F.1, AN8, DOR46F.2, DOR46F.1, Or46F.1, Or46F.2, Or19, CG17848, CG33478, Or46a, Or46aa" "IPR004117:Olfactory receptor, insect" CG33478 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell DRSC07490 K 0.423095351 0.1471332 -0.145503299 0.502398527 2.665955511 0.141930693 FBgn0065977 iab-8E.s iab-8E.s http://flybase.org/reports/FBgn0065977 gene - - - "IAB-8E s, iab-8E s, iab-8E.s, IAB8, 8E" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031536 Cog3 Cog3 http://flybase.org/reports/FBgn0031536 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000329506 protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR007265 dsRNA transport ; GO:0033227 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000329506 Golgi organization ; GO:0007030 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000329506 neurogenesis ; GO:0022008 | inferred from mutant phenotype retrograde transport, vesicle recycling within Golgi ; GO:0000301 | inferred from biological aspect of ancestor with PANTHER:PTN000329506" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR007265 cis-Golgi network ; GO:0005801 | inferred from electronic annotation with InterPro:IPR007265 Golgi transport complex ; GO:0017119 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 Golgi transport complex ; GO:0017119 | inferred from direct assay "Cog3, CG3248, dCOG3, CG 3248, COG3, SEC34" "IPR007265:Conserved oligomeric Golgi complex, subunit 3" CG3248 11-Aug-17 DroID_v2017_08 Drer\cog3 Scer\COG3 Cele\cogc-3 Xtro\cog3 Mmus\Cog3 Hsap\COG3 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC00585 E 0.517332493 0.604583619 1.787207642 -1.055849886 0.306363113 0.396189865 FBgn0034264 Dlish Dachs ligand with SH3s http://flybase.org/reports/FBgn0034264 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:M9MRE4 - apical cortex ; GO:0045179 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG10933, Dlish" IPR001452:SH3 domain CG10933 11-Aug-17 DroID_v2017_08 Drer\arhgef38 - Cele\C26C6.8 Xtro\arhgef38 Mmus\Grap "Hsap\ARHGEF38, Hsap\GRAP" "lethal,partially lethal - majority die,visible,recessive" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0005040 E(tuh-1) Enhancer of tumorous head 1 http://flybase.org/reports/FBgn0005040 - gene - - - E(tuh-1) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004129 l(2)43Cc lethal (2) 43Cc http://flybase.org/reports/FBgn0004129 - gene - - - l(2)43Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015318 U2af65 U2 small nuclear riboprotein auxiliary factor 65 http://flybase.org/reports/FBgn0015318 FBgn0012029 gene poly-pyrimidine tract binding ; GO:0008187 | inferred from direct assay - - "U2AF, U2AF[65], U2af65" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046888 CG31750 - http://flybase.org/reports/FBgn0046888 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | non-traceable author statement taste receptor activity ; GO:0008527 | NOT inferred from sequence or structural similarity biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31750, Gr36d" - CG31750 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033404 Or45a Odorant receptor 45a http://flybase.org/reports/FBgn0033404 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "CG1978, 45a, DOR58, 45C.1, Or45a" "IPR004117:Olfactory receptor, insect" CG1978 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0028712 MI02 MI02 http://flybase.org/reports/FBgn0028712 gene - - - "v(3)03847, MI02" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" FBgn0027845 Bro::Hsap\MYH11 Bro::Hsap\MYH11 http://flybase.org/reports/FBgn0027845 - engineered_fusion_gene - - - "Bro::SMMHC, Bro::Hsap\MYH11" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,ommatidium" FBgn0035547 CG15022 - http://flybase.org/reports/FBgn0035547 protein_coding_gene - - - "BcDNA:RE24507, CG15022" - CG15022 11-Aug-17 DroID_v2017_08 Drer\and3 - - - - - viable DRSC08476 IEK 0.144866205 -2.179511784 0.285832959 -2.084503675 -2.153266597 -0.980194736 FBgn0267892 CR46180 - http://flybase.org/reports/FBgn0267892 pseudogene_attribute - - - "CR46180, CG12717-related" - CR46180 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034501 CG13868 - http://flybase.org/reports/FBgn0034501 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern - "anon-WO0153538.60, CG13868" - CG13868 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0066075 Su(rux)2B Su(rux)2B http://flybase.org/reports/FBgn0066075 gene - second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | non-traceable author statement - Su(rux)2B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013756 Mtor Megator http://flybase.org/reports/FBgn0013756 "FBgn0019919, FBgn0022212" protein_coding_gene ribonucleoprotein complex binding ; GO:0043021 | inferred from sequence or structural similarity with SGD:S000001803 chromatin DNA binding ; GO:0031490 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q86BS3 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VRQ2 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN001052033 protein import into nucleus ; GO:0006606 | inferred from electronic annotation with InterPro:IPR012929 male germ-line stem cell asymmetric division ; GO:0048133 | inferred from mutant phenotype regulation of mitotic spindle organization ; GO:0060236 | inferred from mutant phenotype regulation of chromosome segregation ; GO:0051983 | NOT inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype positive regulation of intracellular protein transport ; GO:0090316 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleocytoplasmic transport ; GO:0006913 | inferred from biological aspect of ancestor with PANTHER:PTN001052033 spindle assembly ; GO:0051225 | inferred from direct assay chromatin organization involved in regulation of transcription ; GO:0034401 | inferred from mutant phenotype regulation of mitotic sister chromatid separation ; GO:0010965 | inferred from mutant phenotype regulation of mitotic spindle elongation ; GO:0032888 | NOT inferred from mutant phenotype regulation of metaphase plate congression ; GO:0090235 | inferred from mutant phenotype regulation of mitotic spindle assembly ; GO:1901673 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype positive regulation of mitotic cell cycle spindle assembly checkpoint ; GO:0090267 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from direct assay germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype positive regulation of mitotic nuclear division ; GO:0045840 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from mutant phenotype positive regulation of cell division ; GO:0051781 | inferred from mutant phenotype nuclear inclusion body ; GO:0042405 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay nuclear periphery ; GO:0034399 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear matrix ; GO:0016363 | inferred from direct assay metaphase plate ; GO:0070090 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay kinetochore ; GO:0000776 | NOT inferred from direct assay nuclear euchromatin ; GO:0005719 | inferred from direct assay mitotic spindle ; GO:0072686 | colocalizes_with inferred from direct assay spindle matrix ; GO:1990047 | inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "Mtor, Bx34, Tpr, TPR, l(2)k03905, CG8274, MTOR, Megator" IPR012929:Nucleoprotein TPR/MLP1 CG8274 11-Aug-17 DroID_v2017_08 "Drer\tprb, Drer\tpra" "Scer\MLP2, Scer\MLP1" Cele\npp-21 Xtro\tpr Mmus\Tpr Hsap\TPR embryonic stage&&larval stage&&adult stage "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,body color defective,partially lethal - majority die,some die during pupal stage" "male germline cell,cyst progenitor cell,germline stem cell,trichogen cell,mesothoracic tergum" FBgn0004581 bgcn benign gonial cell neoplasm http://flybase.org/reports/FBgn0004581 "FBgn0000965, FBgn0001096, FBgn0003066, FBgn0026784, FBgn0034917, FBgn0050170" protein_coding_gene "ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from direct assay helicase activity ; GO:0004386 | inferred from sequence or structural similarity" spermatogenesis ; GO:0007283 | traceable author statement cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cystoblast division ; GO:0007282 | traceable author statement germ cell development ; GO:0007281 | traceable author statement male meiosis ; GO:0007140 | traceable author statement male germline stem cell symmetric division ; GO:0098730 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from direct assay RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000433607 "bcgn, CG10331, CG10330, cg10331, PNBP, b(2)gcn, pep, b(2)cgn, gcn, fs(2)eoQS2, fs(2)eo6, fs(2)eo-C, ben(2)gcn, CG30170, bgcn, Bgcn, BGCN" "IPR002110:Ankyrin repeat, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020683:Ankyrin repeat-containing domain" CG30170 11-Aug-17 DroID_v2017_08 "Drer\tdrd9, Drer\dhx57, Drer\dhx29, Drer\dhx30, Drer\dhx9, Drer\dhx36, Drer\dhx37" "Scer\ECM16, Scer\YLR419W" "Cele\rha-2, Cele\F52B5.3" "Xtro\dhx36, Xtro\tdrd9, Xtro\ythdc2, Xtro\dhx29, Xtro\dhx9, Xtro\dhx30" "Mmus\Tdrd9, Mmus\Ythdc2, Mmus\Dhx30, Mmus\Dhx57, Mmus\Dhx29, Mmus\Dhx37, Mmus\Dhx9, Mmus\Dhx36" "Hsap\DHX37, Hsap\DHX30, Hsap\TDRD9, Hsap\DHX9, Hsap\DHX57, Hsap\YTHDC2, Hsap\DHX36, Hsap\DHX29" " adult stage | male , adult stage && oogenesis stage " " female germline stem cell

, cystoblast

, cystocyte

, germarium

" "male sterile,recessive,female sterile,tumorigenic,viable,hyperplasia,cytokinesis defective,meiotic cell cycle defective" "gonad,germline stem cell,germline cell,male germline stem cell,female germline stem cell,ovary,stem cell fusome,testis,germarium,cystocyte,fusome" FBgn0031012 CG8051 - http://flybase.org/reports/FBgn0031012 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "EP(X)1550, anon-WO03002137.1, CG8051" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8051 11-Aug-17 DroID_v2017_08 "Drer\slc16a6a, Drer\slc16a5b, Drer\slc16a12a, Drer\slc16a9b, Drer\slc16a7, Drer\slc16a9a, Drer\slc16a5a, Drer\slc16a12b, Drer\si:ch211-234h8.7, Drer\slc16a1a" "Scer\MCH2, Scer\ATG22, Scer\MCH4, Scer\ESBP6, Scer\MCH5" "Cele\Y59A8B.21, Cele\slcf-1" "Xtro\slc16a5, Xtro\slc16a7, Xtro\slc16a3, Xtro\slc16a9, Xtro\slc16a2, Xtro\slc16a12" "Mmus\Slc16a12, Mmus\Slc16a9, Mmus\Slc16a6, Mmus\Slc16a14, Mmus\Slc16a13, Mmus\Slc16a4, Mmus\Slc16a5, Mmus\Slc16a11" "Hsap\SLC16A12, Hsap\SLC16A7, Hsap\SLC16A3, Hsap\SLC16A9, Hsap\SLC16A5, Hsap\SLC16A8, Hsap\SLC16A10, Hsap\SLC16A13, Hsap\SLC16A6, Hsap\SLC16A14, Hsap\SLC16A11, Hsap\SLC16A1" viable FBgn0267359 GS16203 - http://flybase.org/reports/FBgn0267359 gene - - - GS16203 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065830 l(2)SH0353 lethal (2) SH0353 http://flybase.org/reports/FBgn0065830 gene - - - "l(2)SH0353, l(2)SH2 0353" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005519 l(2)36Db lethal (2) 36Db http://flybase.org/reports/FBgn0005519 - gene - - - "l(2)36Db, l(2)36D6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036941 CG7335 - http://flybase.org/reports/FBgn0036941 protein_coding_gene fructokinase activity ; GO:0008865 | inferred from sequence or structural similarity with HGNC:6315 ketohexokinase activity ; GO:0004454 | inferred from sequence or structural similarity with HGNC:6315 carbohydrate kinase activity ; GO:0019200 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 fructose metabolic process ; GO:0006000 | inferred from electronic annotation with InterPro:IPR034093 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:6315 carbohydrate phosphorylation ; GO:0046835 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6315 "BcDNA:AT09463, CG7335" "IPR011611:Carbohydrate kinase PfkB, IPR034093:Ketohexokinase, IPR029056:Ribokinase-like, IPR006696:Protein of unknown function DUF423" CG7335 11-Aug-17 DroID_v2017_08 Drer\khk - "Cele\grl-31, Cele\grl-20, Cele\grl-18, Cele\grl-15, Cele\grl-6, Cele\grl-26, Cele\grl-5, Cele\grl-28, Cele\grl-30, Cele\grl-3, Cele\grl-21, Cele\grl-27, Cele\grl-29" Xtro\khk Mmus\Khk Hsap\KHK viable FBgn0265509 CR44371 - http://flybase.org/reports/FBgn0265509 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR44371 - CR44371 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012299 Abd-B::Dfd Abd-B::Dfd http://flybase.org/reports/FBgn0012299 - engineered_fusion_gene - - - Abd-B::Dfd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,heat sensitive" "larval abdominal segment,anterior,filzkorper,ectopic,embryonic abdominal segment,heat sensitive,embryonic mesothoracic segment,embryonic metathoracic segment,T1 beard,spiracular sense organ (obsolete FBbt00000431),embryonic prothoracic segment,abdominal segment,Kolbchen,denticle belt,embryonic head" FBgn0058125 CG40125 - http://flybase.org/reports/FBgn0058125 protein_coding_gene - - - CG40125 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21010 E 0.123257854 0.616020449 1.695077499 -6.089945634 FBgn0027226 l(1)G0307 lethal (1) G0307 http://flybase.org/reports/FBgn0027226 - gene - - - l(1)G0307 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0250837 dUTPase Deoxyuridine triphosphatase http://flybase.org/reports/FBgn0250837 protein_coding_gene dUTP diphosphatase activity ; GO:0004170 | inferred from direct assay dUTP metabolic process ; GO:0046080 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG4584, LD08534, BcDNA:LD08534, UTPase, dUTPase, anon-SAGE:Wang-077" "IPR008181:Deoxyuridine triphosphate nucleotidohydrolase, IPR029054:dUTPase-like, IPR033704:dUTPase, trimeric" CG4584 11-Aug-17 DroID_v2017_08 Drer\dut Scer\DUT1 Cele\dut-1 Xtro\dut Mmus\Dut "Hsap\LOC100506422, Hsap\DUT" FBgn0013566 l(3)78Ab lethal (3) 78Ab http://flybase.org/reports/FBgn0013566 - gene - - - l(3)78Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011808 l(3)s2714 lethal (3) s2714 http://flybase.org/reports/FBgn0011808 - gene - - - l(3)s2714 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005680 disf disordered facets http://flybase.org/reports/FBgn0005680 - gene - compound eye development ; GO:0048749 | inferred from mutant phenotype - "disf, dif" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "eye,ommatidium,eye photoreceptor cell,supernumerary,retina" FBgn0265043 CR44160 - http://flybase.org/reports/FBgn0265043 non_protein_coding_gene - - - CR44160 - CR44160 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011630 l(2)T57d12 lethal (2) T57d12 http://flybase.org/reports/FBgn0011630 FBgn0005177 gene - - - l(2)T57d12 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037944 CG6923 - http://flybase.org/reports/FBgn0037944 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 zinc ion binding ; GO:0008270 | inferred from sequence model proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001102293 CG6923 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6923 11-Aug-17 DroID_v2017_08 "Drer\rnf111, Drer\rnf115, Drer\rnf150, Drer\rnf24, Drer\zswim2, Drer\rnf165b, Drer\rnf11a, Drer\znrf3, Drer\rnf6, Drer\si:ch1073-392o20.1, Drer\zgc:175214, Drer\rnf165a, Drer\si:ch211-81a5.1, Drer\rnf130, Drer\rnf103, Drer\rlim, Drer\si:dkey-51a16.9, Drer\rnf150a, Drer\rnf126, Drer\rnf38, Drer\rnf215, Drer\rnf11b, Drer\rnf32, Drer\rnf44, Drer\wu:fb39e10, Drer\pja2" "Scer\ASR1, Scer\YBR062C" "Cele\Y73C8C.8, Cele\C09E7.7, Cele\sdz-34, Cele\Y73C8C.3, Cele\toe-4, Cele\T22B2.1" "Xtro\rnf126, Xtro\rnf32, Xtro\rnf11.2, Xtro\pja2, Xtro\rnf111, Xtro\rnf149, Xtro\chmp3, Xtro\rnf181, Xtro\rnf11, Xtro\rnf44, Xtro\rlim, Xtro\rnf24, Xtro\znrf3, Xtro\rnf38, Xtro\rnf115" "Mmus\Rnf149, Mmus\Rnf43, Mmus\Rlim, Mmus\Rnf38, Mmus\Pja1, Mmus\Rnf44, Mmus\Zswim2, Mmus\Rnf11, Mmus\Rnf122, Mmus\Rnf103, Mmus\Rnf24, Mmus\Rnf126, Mmus\Rnf32, Mmus\Rnf165, Mmus\4930595M18Rik, Mmus\Rnf215, Mmus\Znrf3, Mmus\Rnf115, Mmus\Rnf6, Mmus\Pja2, Mmus\Rnf150, Mmus\Rnf130, Mmus\Rnf111, Mmus\Rnf181, Mmus\Rnf148" "Hsap\ZSWIM2, Hsap\RNF130, Hsap\PJA2, Hsap\RNF165, Hsap\RNF43, Hsap\RNF44, Hsap\RNF115, Hsap\RNF148, Hsap\RNF149, Hsap\RNF103, Hsap\RLIM, Hsap\RNF122, Hsap\RNF38, Hsap\RNF126, Hsap\CHMP3, Hsap\ZNRF3, Hsap\RNF150, Hsap\RNF32, Hsap\RNF11, Hsap\RNF111, Hsap\PJA1, Hsap\RNF24, Hsap\RNF215, Hsap\RNF181, Hsap\RNF6" viable FBgn0265185 CG44250 - http://flybase.org/reports/FBgn0265185 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3884, CG44250" "IPR024518:Domain of unknown function DUF3421, IPR006616:DM9 repeat" CG44250 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011965 tRNA:Arg-TCG-4-1 transfer RNA:Arginine-TCG 4-1 http://flybase.org/reports/FBgn0011965 "FBgn0011947, FBgn0051593, FBgn0060077" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002681.trna1-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002681, CR31593, tRNA:arg83AB, chr3R.trna1-ArgTCG, tRNA-Arg-TCG-4-1, tRNA:Arg-TCG-4-1, tRNA:R:83AB, CGA" - CR31593 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001787 l(1)M96 lethal (1) M96 http://flybase.org/reports/FBgn0001787 - gene - - - l(1)M96 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052522 CG32522 - http://flybase.org/reports/FBgn0052522 protein_coding_gene - - - CG32522 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032909 CG9266 - http://flybase.org/reports/FBgn0032909 protein_coding_gene - - - "BcDNA:GM06547, CG9266" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026385 Or47b Odorant receptor 47b http://flybase.org/reports/FBgn0026385 - protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay sensory perception of smell ; GO:0007608 | non-traceable author statement integral component of membrane ; GO:0016021 | non-traceable author statement dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "CG13206, 47b, Or47E.2, DOR25, 47E.2, DOR47E.2, Or47b, OR 47b, OR47b, or47b" "IPR004117:Olfactory receptor, insect" CG13206 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000597 E(var)87F Enhancer of variegation 3 http://flybase.org/reports/FBgn0000597 FBgn0000598 gene - - - "E-var(3)3, E(var)8, E(var)3-3, E(var)3, E(var)87F" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0263481 snoRNA:lola-b - http://flybase.org/reports/FBgn0263481 snoRNA_gene - - - snoRNA:lola-b - CR43596 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028982 Spt6 Spt6 http://flybase.org/reports/FBgn0028982 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR028088 chromatin binding ; GO:0003682 | inferred from direct assay nucleosome binding ; GO:0031491 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 transcription factor activity, core RNA polymerase II binding ; GO:0000991 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000015765" regulation of mRNA processing ; GO:0050684 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from mutant phenotype chromatin maintenance ; GO:0070827 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from expression pattern regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 nucleosome organization ; GO:0034728 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 mRNA transcription from RNA polymerase II promoter ; GO:0042789 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from physical interaction with UniProtKB:Q9V460 polytene chromosome puff ; GO:0005703 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay histone locus body ; GO:0035363 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay FACT complex ; GO:0035101 | colocalizes_with inferred from physical interaction with UniProtKB:Q05344 nuclear exosome (RNase complex) ; GO:0000176 | colocalizes_with inferred from direct assay "Spt6, Dspt6, dSpt6, spt 6, CG12225, SPT6, l(1)G0063, spt6, dspt6" "IPR000980:SH2 domain, IPR003029:S1 domain, IPR006641:YqgF/RNase H-like domain, IPR012340:Nucleic acid-binding, OB-fold, IPR017072:Transcription elongation factor Spt6, IPR023323:Tex-like domain, IPR032706:Transcription elongation factor Spt6, helix-hairpin-helix motif, IPR012337:Ribonuclease H-like domain, IPR010994:RuvA domain 2-like, IPR023319:Tex-like protein, HTH domain, IPR028088:Helix-turn-helix DNA-binding domain of Spt6, IPR027999:Death-like domain of Spt6, IPR028083:Spt6 acidic, N-terminal domain, IPR028231:Transcription elongation factor Spt6, YqgF domain, IPR022967:RNA-binding domain, S1" CG12225 11-Aug-17 DroID_v2017_08 Drer\supt6h Scer\SPT6 Cele\emb-5 Xtro\supt6h Mmus\Supt6 Hsap\SUPT6H "viable,lethal - all die before end of embryonic stage,lethal,recessive,some die during embryonic stage,melanotic mass phenotype,visible,lethal - all die before end of larval stage,some die during larval stage" "female germline cell,cuticle | pharate adult stage,abdomen | pharate adult stage,trichome | pharate adult stage,melanotic mass | pharate adult stage" DRSC18836 IEK -1.50883966 3.049083373 -0.259982998 1.840579737 2.792518087 2.602204713 FBgn0031465 CG3123 - http://flybase.org/reports/FBgn0031465 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG3123, gi7295901, gi21064005" "IPR017850:Alkaline-phosphatase-like, core domain, IPR004245:Protein of unknown function DUF229, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG3123 11-Aug-17 DroID_v2017_08 - - "Cele\R03G8.3, Cele\M03F8.5, Cele\Y73F8A.35, Cele\Y38A10A.2, Cele\T07G12.3, Cele\K03A11.4, Cele\T23E1.1, Cele\F15H10.7, Cele\R03G8.1, Cele\F32G8.2, Cele\Y41E3.1, Cele\F10C2.3, Cele\F32D8.2, Cele\F07C3.3" - - - viable FBgn0262816 CG43187 - http://flybase.org/reports/FBgn0262816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43187, DMG8-chr2R.23.004, lincRNA.322" - CG43187 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029745 Rpn13R Regulatory particle non-ATPase 13-related http://flybase.org/reports/FBgn0029745 protein_coding_gene endopeptidase activator activity ; GO:0061133 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 proteasome binding ; GO:0070628 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000004413 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity with SGD:S000004413 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR006773 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006773 proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000004413 proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000259827" "CG6789, Rpn13R" "IPR006773:26S proteasome complex ubiquitin receptor, subunit Rpn13, IPR032368:UCH-binding domain" CG6789 11-Aug-17 DroID_v2017_08 Drer\adrm1 Scer\RPN13 Cele\rpn-13 Xtro\adrm1 Mmus\Adrm1 Hsap\ADRM1 "viable,visible" trichogen cell FBgn0267748 CR46079 - http://flybase.org/reports/FBgn0267748 non_protein_coding_gene - - - CR46079 - CR46079 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002139 l(2)K300 lethal (2) K300 http://flybase.org/reports/FBgn0002139 - gene - - - l(2)K300 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033777 CG17574 - http://flybase.org/reports/FBgn0033777 protein_coding_gene - - - "BcDNA:RH03863, CG17574" - CG17574 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-118j18.2, Drer\glipr2, Drer\crispld1a, Drer\crispld2, Drer\pi15a, Drer\LOC100536500, Drer\r3hdml, Drer\glipr1b, Drer\pi15b, Drer\crispld1b, Drer\glipr2l" "Scer\PRY2, Scer\PRY3, Scer\PRY1" - "Xtro\r3hdml, Xtro\glipr2, Xtro\crispld2, Xtro\crisp1, Xtro\crisp3, Xtro\MGC108118, Xtro\crisp2" "Mmus\Pi16, Mmus\Glipr1, Mmus\Clec18a, Mmus\Pi15, Mmus\Crispld2, Mmus\Glipr1l2, Mmus\Glipr2, Mmus\R3hdml, Mmus\Crispld1, Mmus\Crisp2, Mmus\Crisp4, Mmus\Glipr1l1, Mmus\Crisp1, Mmus\Crisp3" "Hsap\R3HDML, Hsap\CLEC18C, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\CLEC18A, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\GLIPR1, Hsap\CRISPLD1, Hsap\PI15, Hsap\CLEC18B, Hsap\PI16, Hsap\CRISP2, Hsap\GLIPR2" "viable,fertile" FBgn0005339 RD(2) Recovery Disruptor on 2 http://flybase.org/reports/FBgn0005339 - gene - - - RD(2) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015999 l(3)13m-320 lethal (3) 13m-320 http://flybase.org/reports/FBgn0015999 - gene - - - l(3)13m-320 - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0069068 27-25 27-25 http://flybase.org/reports/FBgn0069068 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 27-25 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" FBgn0037424 Osi15 Osiris 15 http://flybase.org/reports/FBgn0037424 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG1157, Osi15, osi15" IPR012464:Protein of unknown function DUF1676 CG1157 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0284246 l(2)k09848 lethal (2) k09848 http://flybase.org/reports/FBgn0284246 protein_coding_gene - ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000411359 muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys "nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000411359 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000411359" "CG7845, l(2)k09848, WDR74, CG745" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG7845 11-Aug-17 DroID_v2017_08 "Drer\wdr61, Drer\wdr74" Scer\NSA1 Cele\T06E6.1 Xtro\wdr74 "Mmus\Wdr74, Mmus\Snrnp40" "Hsap\WDR74, Hsap\SNRNP40" "lethal,recessive" FBgn0283500 Sac1 Sac1 phosphatase http://flybase.org/reports/FBgn0283500 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from sequence or structural similarity with UniProtKB:Q9ES21 phosphatidylinositol phosphate phosphatase activity ; GO:0052866 | inferred from direct assay "cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype inferred from genetic interaction with puc axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype synapse maturation ; GO:0060074 | inferred from mutant phenotype axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype phosphatidylinositol metabolic process ; GO:0046488 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype" endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with UniProtKB:Q9ES21 sensory dendrite ; GO:0071683 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "Sac1, impatent, sac1, CG9128, dsac1, l(3)2107" IPR002013:SAC domain CG9128 11-Aug-17 DroID_v2017_08 "Drer\sacm1lb, Drer\sacm1la" Scer\SAC1 Cele\sac-1 Xtro\sacm1l Mmus\Sacm1l "Hsap\INPP5F, Hsap\SACM1L" "visible,lethal,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,partially lethal,increased cell death" "eye,embryonic/first instar larval cuticle,dorsal,dorsal hair,amnioserosa,NMJ bouton,ommatidium,interommatidial bristle,NMJ bouton | larval stage" FBgn0005573 l(3)85Ei lethal (3) 85Ei http://flybase.org/reports/FBgn0005573 - gene - - - l(3)85Ei - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265661 CR44468 - http://flybase.org/reports/FBgn0265661 non_protein_coding_gene - - - "lincRNA.345, CR44468" - CR44468 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000336 cmt comet http://flybase.org/reports/FBgn0000336 - gene - - - cmt - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "wing & trichome,cuticle" FBgn0010139 l(2)DTS20 lethal (2) DTS20 http://flybase.org/reports/FBgn0010139 - gene - - - "DTS-L20, l(2)DTS20" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,recessive" "adult abdomen,dorsal" FBgn0000579 Eno Enolase http://flybase.org/reports/FBgn0000579 "FBgn0045789, FBgn0045874" protein_coding_gene "phosphopyruvate hydratase activity ; GO:0004634 | inferred from electronic annotation with InterPro:IPR000941 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR000941, InterPro:IPR020809, InterPro:IPR020810, InterPro:IPR020811" "glycolytic process ; GO:0006096 | inferred from electronic annotation with InterPro:IPR000941, InterPro:IPR020809, InterPro:IPR020810, InterPro:IPR020811 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" "phosphopyruvate hydratase complex ; GO:0000015 | inferred from electronic annotation with InterPro:IPR000941, InterPro:IPR020809, InterPro:IPR020810, InterPro:IPR020811 lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay" "Eno, CG17654, T18, CT32526, Eno2, ENOA, BEST:LD15491, anon-WO0153538.76, eno" "IPR000941:Enolase, IPR029017:Enolase N-terminal domain-like, IPR029065:Enolase C-terminal domain-like, IPR020809:Enolase, conserved site, IPR020810:Enolase, C-terminal TIM barrel domain, IPR020811:Enolase, N-terminal, IPR034390:Enolase-like superfamily" CG17654 11-Aug-17 DroID_v2017_08 "Drer\eno1a, Drer\eno3, Drer\eno1b, Drer\eno2, Drer\eno4" "Scer\ERR1, Scer\ERR2, Scer\ENO2, Scer\ENO1, Scer\ERR3" Cele\enol-1 "Xtro\eno1, Xtro\eno4" "Mmus\Eno1, Mmus\Eno2, Mmus\Eno4, Mmus\Eno3, Mmus\Eno1b" "Hsap\ENO1, Hsap\ENO2, Hsap\ENO3, Hsap\ENO4" larval stage | third instar dorsal mesothoracic disc

"lethal,viable,fertile" FBgn0065961 l(2)SH0032 lethal (2) SH0032 http://flybase.org/reports/FBgn0065961 gene - - - "l(2)SH0032, l(2)SH2 0032" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004976 Apart Apart http://flybase.org/reports/FBgn0004976 - gene - - - "Apt, apt, Apart" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant,viable,good,fertile" wing FBgn0028237 l(3)S002309 lethal (3) S002309 http://flybase.org/reports/FBgn0028237 gene - - - "0023/09, l(3)S002309" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0041112 l(3)cl-R3 lethal (3) cell lethal R3 http://flybase.org/reports/FBgn0041112 gene - - - "cl3R3, l(3)cl-R3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cell lethalcell lethal,somatic clone" FBgn0065873 l(2)SH0251 lethal (2) SH0251 http://flybase.org/reports/FBgn0065873 gene - - - "l(2)SH0251, l(2)SH2 0251" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259391 C432 - http://flybase.org/reports/FBgn0259391 gene - - - C432 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing hair FBgn0262827 CG43198 - http://flybase.org/reports/FBgn0262827 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43198, DMG6-MB6.chrX.13.005" - CG43198 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038865 cDIP Common Dpr-interacting protein http://flybase.org/reports/FBgn0038865 protein_coding_gene - - - "CT11359, CG10824, DIPc, 10824, cDIP" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG10824 11-Aug-17 DroID_v2017_08 "Drer\tlr4al, Drer\tlr4bb, Drer\lrrc15, Drer\zgc:153913, Drer\lrrc17, Drer\lrrc6, Drer\tlr4ba" - - Xtro\lrrc15 "Mmus\Cpn2, Mmus\Lrrc17, Mmus\Lrrc15, Mmus\Lrrc6, Mmus\Gp5" "Hsap\GP5, Hsap\LRRC6, Hsap\LRRC15, Hsap\LRRC17, Hsap\CPN2" "partially lethal - majority die,some die during pupal stage" FBgn0002568 luc luckenhaft http://flybase.org/reports/FBgn0002568 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available luc - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle,embryonic head,embryonic segment" FBgn0029506 Tsp42Ee Tetraspanin 42Ee http://flybase.org/reports/FBgn0029506 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model fusome ; GO:0045169 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG10106, Dm.Tsp42Ee, BcDNA:LD16071, anon-WO0118547.151, Tsp42Ee" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG10106 11-Aug-17 DroID_v2017_08 Drer\cd63 - "Cele\tsp-1, Cele\tsp-2, Cele\tsp-7, Cele\tsp-3, Cele\tsp-14" Xtro\cd63 Mmus\Cd63 Hsap\CD63 viable FBgn0000872 fs(1)M68 female sterile (1) M68 http://flybase.org/reports/FBgn0000872 - gene - - - fs(1)M68 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0035647 CG10486 - http://flybase.org/reports/FBgn0035647 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG10486 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG10486 11-Aug-17 DroID_v2017_08 "Drer\LOC100334012, Drer\LOC101884074, Drer\slc22a13, Drer\oatx, Drer\slc22a21, Drer\zgc:175176, Drer\zmp:0000001102, Drer\slc22a7b.1, Drer\slc22a7b.3, Drer\slc22a6l, Drer\slc22a5, Drer\sv2, Drer\slc22a7b.2" "Scer\QDR3, Scer\TPO2, Scer\TPO1, Scer\HXT2, Scer\YHK8, Scer\FLR1, Scer\GIT1, Scer\DTR1, Scer\QDR2, Scer\HXT9, Scer\AQR1, Scer\TPO3, Scer\HXT5, Scer\PHO84, Scer\QDR1" "Cele\C46C2.2, Cele\Y51A2D.18, Cele\B0361.11, Cele\Y57G11C.23, Cele\ZK892.3, Cele\T22F7.1, Cele\Y66D12A.13, Cele\B0252.3, Cele\C53B4.1, Cele\oct-1, Cele\C06H5.6" Xtro\slc22a6 "Mmus\Slc22a30, Mmus\Slc22a27, Mmus\Slc22a26, Mmus\Slc22a5, Mmus\Sv2c, Mmus\Slc22a21, Mmus\Slc22a6, Mmus\Slc22a19, Mmus\Slc22a20, Mmus\Svop, Mmus\Slc22a14, Mmus\Slc22a16, Mmus\Slc22a2, Mmus\Slc22a23, Mmus\Slc22a4, Mmus\Slc22a29, Mmus\Slc22a22, Mmus\Slc22a8, Mmus\Slc22a7, Mmus\Slc22a28" "Hsap\SLC22A24, Hsap\SLC22A12, Hsap\SLC22A11, Hsap\SLC22A5, Hsap\SLC22A4, Hsap\SLC22A9, Hsap\SLC22A8, Hsap\SVOP, Hsap\SV2C, Hsap\SLC22A6, Hsap\SLC22A25, Hsap\SV2B, Hsap\SLC22A7, Hsap\SLC22A10, Hsap\SLC22A23, Hsap\SLC22A1, Hsap\SLC22A2" "viable,fertile" FBgn0036282 Smyd4-2 "SET and MYND domain containing, class 4, member 2" http://flybase.org/reports/FBgn0036282 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with ebi histone deacetylase binding ; GO:0042826 | inferred from physical interaction with HDAC1 inferred from physical interaction with HDAC3 negative regulation of gene expression ; GO:0010629 | inferred from direct assay compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype eclosion ; GO:0007562 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG14122, dSmyd4, Smyd4-2, Smyd4" IPR011990:Tetratricopeptide-like helical domain CG14122 11-Aug-17 DroID_v2017_08 "Drer\smyd3, Drer\smyd4, Drer\smyd1b, Drer\smyd2b, Drer\smyd2a, Drer\smyd1a" "Scer\SET6, Scer\SET5" "Cele\set-3, Cele\set-18, Cele\set-10" "Xtro\smyd1, Xtro\smyd5, Xtro\smyd4" "Mmus\Smyd2, Mmus\Smyd4, Mmus\Zmynd15, Mmus\Smyd3, Mmus\Smyd1, Mmus\Smyd5" "Hsap\SMYD5, Hsap\SMYD2, Hsap\SMYD1, Hsap\ZMYND15, Hsap\SMYD3, Hsap\SMYD4" "viable,fertile,lethal,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0051678 CG31678 - http://flybase.org/reports/FBgn0051678 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "38D.30, CG17466, CG17465, CG31678" "IPR008979:Galactose-binding domain-like, IPR012919:SUN domain" CG31678 11-Aug-17 DroID_v2017_08 Drer\suco Scer\SLP1 Cele\suco-1 Xtro\suco Mmus\Suco Hsap\SUCO "viable,fertile,visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0031146 CG15449 - http://flybase.org/reports/FBgn0031146 protein_coding_gene - - - CG15449 - CG15449 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040990 CG15156 - http://flybase.org/reports/FBgn0040990 protein_coding_gene - - - CG15156 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085213 CG34184 - http://flybase.org/reports/FBgn0085213 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34184 IPR006631:Protein of unknown function DM4/12 CG34184 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262983 CG43291 - http://flybase.org/reports/FBgn0262983 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43291 "IPR031986:Serine protease gd, N-terminal domain" CG43291 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259609 B1501 - http://flybase.org/reports/FBgn0259609 gene - - - B1501 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,mediproboscis,proboscis" FBgn0263143 vret vreteno http://flybase.org/reports/FBgn0263143 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with fs(1)Yb inferred from physical interaction with Hsp27 inferred from physical interaction with piwi inferred from physical interaction with CG9281 inferred from physical interaction with BoYb inferred from physical interaction with armi inferred from physical interaction with SoYb "regulation of gene silencing by RNA ; GO:0060966 | inferred from mutant phenotype negative regulation of transposition, RNA-mediated ; GO:0010526 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype" P granule ; GO:0043186 | inferred from direct assay Yb body ; GO:0070725 | inferred from physical interaction with fs(1)Yb inferred from physical interaction with armi cytoplasm ; GO:0005737 | inferred from direct assay "CG4771, vret" IPR002999:Tudor domain CG4771 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061063 l(3)S022122b lethal (3) S022122b http://flybase.org/reports/FBgn0061063 gene - - - "0221/22, l(3)S022122b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085236 CG34207 - http://flybase.org/reports/FBgn0085236 protein_coding_gene - - - CG34207 - CG34207 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011957 tRNA:Arg-ACG-1-2 transfer RNA:Arginine-ACG 1-2 http://flybase.org/reports/FBgn0011957 "FBgn0003757, FBgn0011947, FBgn0050306, FBgn0050512, FBgn0060090" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "Arg-tRNA, tRNA[arg], tRNA[Arg][[2]], AE002769.trna12-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002769-c, tRNA:arg2:42Ac, CR30306, CR30512, chr2R.trna3-ArgACG, tRNA-Arg-ACG-1-2, tRNA:Arg-ACG-1-2, tRNA:R2:42Ac, CGU" - CR30512 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010693 l(2)s4199 lethal (2) s4199 http://flybase.org/reports/FBgn0010693 - gene - - - l(2)s4199 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259341 C192 - http://flybase.org/reports/FBgn0259341 gene - - - C192 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0261068 LSm7 Like Sm 7 http://flybase.org/reports/FBgn0261068 protein_coding_gene RNA binding ; GO:0003723 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000058283 RNA binding ; GO:0003723 | contributes_to inferred from sequence or structural similarity with SGD:S000005091 "nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from electronic annotation with InterPro:IPR017132 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000005091 inferred from sequence or structural similarity with protein_id:AAD56231 neurogenesis ; GO:0022008 | inferred from mutant phenotype RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000058283" Lsm1-7-Pat1 complex ; GO:1990726 | inferred from biological aspect of ancestor with PANTHER:PTN000058361 U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000058284 U6 snRNP ; GO:0005688 | inferred from sequence or structural similarity with SGD:S000005091 U6 snRNP ; GO:0005688 | inferred from biological aspect of ancestor with PANTHER:PTN000058361 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000058284 precatalytic spliceosome ; GO:0071011 | inferred from direct assay spliceosomal tri-snRNP complex ; GO:0097526 | inferred from biological aspect of ancestor with PANTHER:PTN000058361 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG13277, LSm7, BcDNA:RH73529" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR017132:Sm-like protein Lsm7" CG13277 11-Aug-17 DroID_v2017_08 "Drer\lsm7, Drer\snrpg" Scer\LSM7 Cele\lsm-7 "Xtro\snrpg, Xtro\lsm7" "Mmus\Snrpg, Mmus\Lsm7" "Hsap\SNRPG, Hsap\LSM7" DRSC02251 K 0.204611123 1.229106634 0.286358835 1.460116065 -1.720146305 0.118562524 FBgn0000943 fs(2)A13 female sterile (2) A13 http://flybase.org/reports/FBgn0000943 - gene - - - fs(2)A13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" "female reproductive system,maternal effect,spindle | maternal effect" FBgn0036044 Zasp67 Z band alternatively spliced PDZ-motif protein 67 http://flybase.org/reports/FBgn0036044 protein_coding_gene - myofibril assembly ; GO:0030239 | inferred from mutant phenotype - "CG14168, Zasp67" "IPR017351:LIM and senescent cell antigen-like-containing domain protein 1, IPR001478:PDZ domain" CG14168 11-Aug-17 DroID_v2017_08 "Drer\lims2, Drer\lims1" - "Cele\pin-2, Cele\unc-97" Xtro\pdlim7 "Mmus\Lims1, Mmus\Pdlim2, Mmus\Pdlim7, Mmus\Lims2" "Hsap\LIMS4, Hsap\LIMS3, Hsap\PDLIM2, Hsap\LIMS2, Hsap\LIMS1" "viable,flight defective" FBgn0259276 EP-67 - http://flybase.org/reports/FBgn0259276 gene - - - EP-67 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,planar polarity defective,lethal" wing FBgn0015426 l(1)1CDc lethal (1) 1CDc http://flybase.org/reports/FBgn0015426 - gene - - - l(1)1CDc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037994 eIF3d2 eukaryotic translation initiation factor 3 subunit d2 http://flybase.org/reports/FBgn0037994 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity inferred from sequence or structural similarity with protein_id:BAA25327 translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000273956 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with UniProtKB:Q9VCK0 translational initiation ; GO:0006413 | inferred from sequence or structural similarity regulation of translational initiation ; GO:0006446 | inferred from sequence or structural similarity with UniProtKB:Q9VCK0 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with UniProtKB:Q9VCK0 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000273956 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity "149735_at, eIF3-S7, CG4810, eIF3d2" IPR007783:Eukaryotic translation initiation factor 3 subunit D CG4810 11-Aug-17 DroID_v2017_08 Drer\eif3d - Cele\eif-3.D Xtro\eif3d Mmus\Eif3d Hsap\EIF3D viable FBgn0004125 l(2)43Bd lethal (2) 43Bd http://flybase.org/reports/FBgn0004125 - gene - - - "43Bd, l(2)43Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041713 yellow-c yellow-c http://flybase.org/reports/FBgn0041713 protein_coding_gene - cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG4182, BG:DS00929.8, anon-EST:ParkEST125, yellow-c, yell-c" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG4182 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\F49E11.8, Cele\T27A1.3, Cele\fbxa-76, Cele\C24H12.1" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 FBgn0030819 CG8926 - http://flybase.org/reports/FBgn0030819 protein_coding_gene - - - CG8926 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040942 CG12643 - http://flybase.org/reports/FBgn0040942 protein_coding_gene - - - CG12643 - CG12643 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0058000 CG40000 - http://flybase.org/reports/FBgn0058000 protein_coding_gene - - - CG40000 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037796 CG12814 - http://flybase.org/reports/FBgn0037796 protein_coding_gene - - - "CG12815, CG12814" IPR001507:Zona pellucida domain CG12814 11-Aug-17 DroID_v2017_08 "Drer\zgc:153932, Drer\si:ch211-229d2.5, Drer\zmp:0000001031, Drer\si:ch211-103f14.3" - "Cele\cutl-4, Cele\cutl-24, Cele\cutl-14, Cele\cutl-15, Cele\cutl-1, Cele\cutl-13, Cele\cutl-10, Cele\cut-5, Cele\cutl-28, Cele\cut-1, Cele\cut-6, Cele\T01D1.8, Cele\cutl-2, Cele\cutl-5, Cele\cutl-25, Cele\ram-5, Cele\cutl-6, Cele\cutl-20, Cele\cutl-11, Cele\cutl-9, Cele\cutl-22, Cele\cutl-12, Cele\cutl-8, Cele\cutl-29, Cele\cutl-26, Cele\dpy-1, Cele\cutl-7, Cele\cut-3, Cele\cutl-16, Cele\cut-4, Cele\F46G11.6, Cele\cutl-19, Cele\cutl-3" "Xtro\MGC89178, Xtro\thdl18, Xtro\thdl17" - - viable FBgn0259658 B1509 - http://flybase.org/reports/FBgn0259658 gene - - - B1509 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,unguis,antennal segment,arista,wing,scutellum" FBgn0060607 l(3)S090605 lethal (3) S090605 http://flybase.org/reports/FBgn0060607 gene - - - "0906/05, l(3)S090605" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262969 CR43280 - http://flybase.org/reports/FBgn0262969 non_protein_coding_gene - - - "CR43280, lincRNA.605" - CR43280 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014066 Su(tor)3-333 Su(tor)3-333 http://flybase.org/reports/FBgn0014066 - gene - - - Su(tor)3-333 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283536 Vha13 Vacuolar H[+] ATPase 13kD subunit http://flybase.org/reports/FBgn0283536 protein_coding_gene "hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ; GO:0016820 | inferred from electronic annotation with InterPro:IPR005124 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181" "proton transport ; GO:0015992 | inferred from electronic annotation with InterPro:IPR005124 embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype proton transport ; GO:0015992 | inferred from sequence or structural similarity ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype" "vacuolar proton-transporting V-type ATPase complex ; GO:0016471 | inferred from electronic annotation with InterPro:IPR005124 vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype" "CG6213, Vha13, cnj, vha13, VhaG, l(3)05113, BcDNA:AT14009, ATP6V1G, chr3R:15469897..15470039, conjoined" IPR005124:Vacuolar (H+)-ATPase G subunit CG6213 11-Aug-17 DroID_v2017_08 Drer\atp6v1g1 Scer\VMA10 Cele\vha-10 "Xtro\atp6v1g2, Xtro\atp6v1g3, Xtro\atp6v1g1" "Mmus\Atp6v1g3, Mmus\Atp6v1g1, Mmus\Atp6v1g2" "Hsap\ATP6V1G1, Hsap\ATP6V1G2, Hsap\ATP6V1G3" "embryonic/larval dorsal trunk,terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0267073 CR45517 - http://flybase.org/reports/FBgn0267073 non_protein_coding_gene - - - CR45517 - CR45517 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064172 l(2)c855 lethal (2) c855 http://flybase.org/reports/FBgn0064172 gene - - - l(2)c855 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024609 olfJ106 olfactory J106 http://flybase.org/reports/FBgn0024609 - gene - - - olfJ106 - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0082614 Su(PDS)P80 Su(PDS)P80 http://flybase.org/reports/FBgn0082614 gene - - - Su(PDS)P80 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,non-suppressor of variegation" FBgn0040330 EY2-8 EY2-8 http://flybase.org/reports/FBgn0040330 gene - - - EY2-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010066 M(3)32l M(3)32l http://flybase.org/reports/FBgn0010066 - gene - - - M(3)32l - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036847 CG11577 - http://flybase.org/reports/FBgn0036847 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - endomembrane system ; GO:0012505 | inferred from direct assay "anon-WO0118547.323, CG11577" IPR021852:Domain of unknown function DUF3456 CG11577 11-Aug-17 DroID_v2017_08 "Drer\tnrc5, Drer\cnpy4" - Cele\C11H1.7 - "Mmus\Cnpy3, Mmus\Cnpy4" "Hsap\CNPY4, Hsap\CNPY3" viable FBgn0016968 wan wanderer http://flybase.org/reports/FBgn0016968 - gene - peripheral nervous system development ; GO:0007422 | traceable author statement - wan - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" peripheral nervous system FBgn0264552 CG43931 - http://flybase.org/reports/FBgn0264552 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43931 - CG43931 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016701 Rab4 Rab4 http://flybase.org/reports/FBgn0016701 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 protein binding ; GO:0005515 | inferred from physical interaction with Vps52 inferred from physical interaction with CG31064" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 regulation of endocytosis ; GO:0030100 | inferred from biological aspect of ancestor with PANTHER:PTN001530980 endocytosis ; GO:0006897 | traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay endosome ; GO:0005768 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 recycling endosome ; GO:0055037 | inferred from direct assay "CG4921, DmRab4, DRAB4, Rab4, rab4, CG 4921, RAB4c, Q7KY04" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4921 11-Aug-17 DroID_v2017_08 "Drer\rab14, Drer\rab2a, Drer\rab14l, Drer\rab4a, Drer\rab4b" "Scer\YPT32, Scer\YPT31" Cele\unc-108 "Xtro\rab14, Xtro\rab2b, Xtro\rab4b, Xtro\rab2a" "Mmus\Rab4a, Mmus\Mia, Mmus\Rab14, Mmus\Rab4b, Mmus\Rab2a" "Hsap\RAB2A, Hsap\MIA, Hsap\RAB14, Hsap\EGLN2, Hsap\RAB4A, Hsap\RAB2B, Hsap\RAB4B" "viable,neuroanatomy defective" embryonic/larval glial cell FBgn0037501 Ir84a Ionotropic receptor 84a http://flybase.org/reports/FBgn0037501 protein_coding_gene "ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR019594 extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 extracellular phenylacetaldehyde-gated ion channel activity ; GO:0036082 | contributes_to inferred from direct assay co-receptor binding ; GO:0039706 | inferred from physical interaction with Ir8a olfactory receptor activity ; GO:0004984 | contributes_to inferred from direct assay extracellular phenylacetaldehyde-gated ion channel activity ; GO:0036082 | inferred from direct assay" detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from mutant phenotype transmission of nerve impulse ; GO:0019226 | inferred from mutant phenotype receptor complex ; GO:0043235 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model dendrite terminus ; GO:0044292 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay sensory dendrite ; GO:0071683 | inferred from direct assay "Ir84a, CT28433, IR84a, CG10101, DmelIR84a" "IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG10101 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-251b21.1, Drer\si:dkey-183j2.10, Drer\grik1b, Drer\grik1a, Drer\grik4" - "Cele\glr-4, Cele\glr-5, Cele\glr-8" - "Mmus\Grik4, Mmus\Grik1" "Hsap\GRIK1, Hsap\GRIK4" "smell perception defective,recessive,neurophysiology defective,courtship behavior defective,male limited,viable,visible,body color defective" "trichogen cell,mesothoracic tergum,sensillum coeloconicum of antennal segment 3" FBgn0061139 l(3)S000627b lethal (3) S000627b http://flybase.org/reports/FBgn0061139 gene - - - "0006/27, l(3)S000627b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005531 l(2)52ACh lethal (2) 52ACh http://flybase.org/reports/FBgn0005531 - gene - - - l(2)52ACh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016805 l(1)K7 lethal (1) K7 http://flybase.org/reports/FBgn0016805 - gene - - - "l(1)K7, K7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065652 l(2)SH0732 lethal (2) SH0732 http://flybase.org/reports/FBgn0065652 gene - - - "l(2)SH0732, l(2)SH2 0732" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030800 Nprl2 Nitrogen permease regulator-like 2 http://flybase.org/reports/FBgn0030800 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Nprl3 negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype negative regulation of TORC1 signaling ; GO:1904262 | inferred from mutant phenotype TORC1 signaling ; GO:0038202 | inferred from mutant phenotype cellular response to nitrogen starvation ; GO:0006995 | inferred from biological aspect of ancestor with PANTHER:PTN000988255 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from genetic interaction with mio inferred from genetic interaction with Nup44A positive regulation of autophagy ; GO:0010508 | inferred from biological aspect of ancestor with PANTHER:PTN000988255 oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of TORC1 signaling ; GO:1904262 | inferred from genetic interaction with Wdr24 regulation of autophagosome assembly ; GO:2000785 | inferred from biological aspect of ancestor with PANTHER:PTN000988255 autolysosome ; GO:0044754 | inferred from direct assay Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000000788 cytoplasm ; GO:0005737 | inferred from direct assay Iml1 complex ; GO:1990130 | traceable author statement Seh1-associated complex ; GO:0035859 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG9104, nprl2, npr2, Nprl2, NPR2, Nplr2" IPR009348:Nitrogen permease regulator 2 CG9104 11-Aug-17 DroID_v2017_08 "Drer\zmynd10, Drer\nprl2" Scer\NPR2 Cele\nprl-2 "Xtro\nprl2, Xtro\zmynd10" Mmus\Nprl2 "Hsap\NPRL2, Hsap\ZMYND10" viable FBgn0027654 jdp jdp http://flybase.org/reports/FBgn0027654 - protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with ECOGENE:EG10240 protein folding ; GO:0006457 | inferred from sequence or structural similarity with ECOGENE:EG10240 cellular_component ; GO:0005575 | no biological data available "dJDP, p25a, CG2239, jdp, JDP" IPR001623:DnaJ domain CG2239 11-Aug-17 DroID_v2017_08 "Drer\dnajc30b, Drer\dnajc12, Drer\dnajc4, Drer\dnajc30" "Scer\CAJ1, Scer\DJP1" Cele\K07F5.16 "Xtro\dnajc4, Xtro\dnajc17, Xtro\dnajc12" "Mmus\Dnajc12, Mmus\Dnajc17" "Hsap\DNAJC12, Hsap\DNAJC17" "viable,fertile" FBgn0003331 scg scrambled egg http://flybase.org/reports/FBgn0003331 - gene - - - scg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035964 Dhpr Dihydropteridine reductase http://flybase.org/reports/FBgn0035964 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "CG4665, DHPR, Dhpr" "IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site, IPR002347:Short-chain dehydrogenase/reductase SDR" CG4665 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-40h17.4, Drer\qdprb2, Drer\qdpra, Drer\zgc:171517, Drer\qdprb1" - Cele\qdpr-1 Xtro\qdpr Mmus\Qdpr Hsap\QDPR adult stage adult head

FBgn0051969 CR31969 - http://flybase.org/reports/FBgn0051969 non_protein_coding_gene - - - "BcDNA:LP03459, CR31969" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016857 l(1)N4 lethal (1) N4 http://flybase.org/reports/FBgn0016857 - gene - - - "l(1)N4, N4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053237 Ste:CG33237 Ste:CG33237 http://flybase.org/reports/FBgn0053237 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG32605, CG33237, Ste:CG33237" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33237 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0040610 CG14263 - http://flybase.org/reports/FBgn0040610 protein_coding_gene - - - CG14263 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003743 trb thread bristle http://flybase.org/reports/FBgn0003743 - gene - - - trb - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male fertile,viable,male,visible,body color defective" "macrochaeta,microchaeta,wing,wing vein,trident" FBgn0015793 Rab19 Rab19 http://flybase.org/reports/FBgn0015793 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with GCC88, cbs GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with plx" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 neuronal cell body ; GO:0043025 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 recycling endosome ; GO:0055037 | inferred from direct assay "AAF50452, DmRab19, DRabRP3, DRABR3, Rab-r3, CG7062, Rab19, Rab19/RP3, rab19, Rab19s, Rab-RP3, O18339" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7062 11-Aug-17 DroID_v2017_08 "Drer\rab1aa, Drer\rab43, Drer\rab33a, Drer\zgc:171927, Drer\rabl6a, Drer\rab1bb, Drer\zgc:101559, Drer\rabl6b, Drer\rab33ba, Drer\rab12, Drer\rab19, Drer\rab1ab, Drer\rab1ba" "Scer\YPT1, Scer\YPT31, Scer\YPT32" Cele\rab-19 "Xtro\rab1a, Xtro\rab19, Xtro\rab33b, Xtro\rabl6, Xtro\rab33a" "Mmus\Rabl6, Mmus\Rab43, Mmus\Rab12, Mmus\Rab19, Mmus\Rab33b, Mmus\Rab1b, Mmus\Rab33a, Mmus\Rab1a" "Hsap\RAB33B, Hsap\RAB12, Hsap\RABL6, Hsap\RAB1B, Hsap\RAB19, Hsap\RAB1A, Hsap\ISY1, Hsap\RAB43, Hsap\RAB33A" viable FBgn0262535 CG43089 - http://flybase.org/reports/FBgn0262535 protein_coding_gene - "ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR016072, InterPro:IPR016073" - "CG43089, lincRNA.427" "IPR011333:SKP1/BTB/POZ domain, IPR016073:SKP1 component, POZ domain, IPR001232:S-phase kinase-associated protein 1-like" CG43089 11-Aug-17 DroID_v2017_08 Drer\skp1 Scer\SKP1 "Cele\skr-17, Cele\skr-6, Cele\skr-16, Cele\skr-15, Cele\skr-4, Cele\skr-1, Cele\skr-10, Cele\skr-12, Cele\skr-19, Cele\skr-21, Cele\skr-14, Cele\skr-9, Cele\skr-3, Cele\skr-18, Cele\skr-7, Cele\skr-5, Cele\skr-20, Cele\skr-8, Cele\skr-13, Cele\skr-2" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 FBgn0065607 l(2)SH0843 lethal (2) SH0843 http://flybase.org/reports/FBgn0065607 gene - - - "l(2)SH0843, l(2)SH2 0843" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038582 CG7988 - http://flybase.org/reports/FBgn0038582 protein_coding_gene molecular_function ; GO:0003674 | no biological data available circadian rhythm ; GO:0007623 | inferred from sequence or structural similarity with UniProtKB:Q8GWZ6 cellular_component ; GO:0005575 | no biological data available CG7988 "IPR012942:Sensitivity To Red Light Reduced-like, SRR1" CG7988 11-Aug-17 DroID_v2017_08 Drer\srrd Scer\BER1 - Xtro\srrd Mmus\Srrd Hsap\SRRD viable FBgn0058315 CG40315 - http://flybase.org/reports/FBgn0058315 protein_coding_gene - - - CG40315 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028585 l(3)rI165 lethal (3) rI165 http://flybase.org/reports/FBgn0028585 gene - - - "l(?)rI165, l(3)rI165" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051451 CR31451 - http://flybase.org/reports/FBgn0051451 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "gh16531, anon-EST:Posey277, BcDNA:GH16531, CG31451, CR31451" - CR31451 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054012 CG34012 - http://flybase.org/reports/FBgn0054012 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1014, CG34012" - CG34012 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060363 l(3)S138613a lethal (3) S138613a http://flybase.org/reports/FBgn0060363 gene - - - "1386/13, l(3)S138613a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022772 Orc1 Origin recognition complex subunit 1 http://flybase.org/reports/FBgn0022772 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR001025 DNA endoreduplication ; GO:0042023 | NOT inferred from mutant phenotype DNA amplification ; GO:0006277 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from direct assay nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay "ORC, rDmORC, DmORC1, ORC1, dORC1, CG10667, Orc1, DmOrc1p, orc1, DmOrc1" "IPR001025:Bromo adjacent homology (BAH) domain, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR015163:Cdc6, C-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10667 11-Aug-17 DroID_v2017_08 "Drer\cdc6, Drer\orc1" "Scer\CDC6, Scer\ORC1, Scer\SIR3" "Cele\cdc-6, Cele\orc-1" Xtro\orc1 "Mmus\Cdc6, Mmus\Orc1" "Hsap\CDC6, Hsap\ORC1" embryonic stage && larval stage "lethal,polyphasic,female sterile,male sterile,visible,neuroanatomy defective,viable" "eye,ommatidium,interommatidial bristle,eye-antennal disc,posterior,morphogenetic furrow,stage S10B oocyte,follicle cell & nucleus,egg,chorion,dorsal appendage,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC07496 K -1.173812525 -0.393555002 -0.644168193 -1.49636062 0.220241507 1.822720547 FBgn0082339 HM617 HM617 http://flybase.org/reports/FBgn0082339 gene - - - HM617 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082980 snoRNA:Psi28S-2996 snoRNA:Psi28S-2996 http://flybase.org/reports/FBgn0082980 snoRNA_gene - - - "snoRNA:Psi28S-2996, psi28s-2996, Psi 28S-2996, snoRNA:RpL5-a" - CR43565 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084040 CG41480 - http://flybase.org/reports/FBgn0084040 protein_coding_gene - - - CG41480 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014287 l(3)64Af lethal (3) 64Af http://flybase.org/reports/FBgn0014287 - gene - - - l(3)64Af - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004564 l(3)63Bh lethal (3) 63Bh http://flybase.org/reports/FBgn0004564 - gene - - - l(3)63Bh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0065312 l(2)SH1938 lethal (2) SH1938 http://flybase.org/reports/FBgn0065312 gene - - - "l(2)SH1938, l(2)SH2 1938" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035384 CG2113 - http://flybase.org/reports/FBgn0035384 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity with MGI:MGI:2444891 "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with MGI:MGI:2444891" actin cytoskeleton ; GO:0015629 | inferred from sequence or structural similarity with MGI:MGI:2444891 "BcDNA:AT18037, CG2113" IPR027817:Costars domain CG2113 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-29b11.3, Drer\abraa, Drer\abrab, Drer\abracl" - "Cele\clec-119, Cele\clec-73, Cele\clec-117, Cele\clec-151, Cele\clec-153, Cele\tag-243, Cele\F36F2.1, Cele\clec-123, Cele\clec-175, Cele\clec-79" Xtro\abra "Mmus\Abracl, Mmus\Abra" "Hsap\ABRA, Hsap\ABRACL" FBgn0267660 CR45998 - http://flybase.org/reports/FBgn0267660 non_protein_coding_gene - - - CR45998 - CR45998 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265889 CR44678 - http://flybase.org/reports/FBgn0265889 non_protein_coding_gene - - - CR44678 - CR44678 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066314 Aexon.s Aexon.s http://flybase.org/reports/FBgn0066314 gene - - - Aexon.s - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015372 RabX1 RabX1 http://flybase.org/reports/FBgn0015372 FBgn0034872 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | traceable author statement GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype synapse ; GO:0045202 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 "AAF47018, DmRabX1, l(2)k06908, chr, CG3870, RabX1, rabX1, chrw, RAB5c, Chrw" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3870 11-Aug-17 DroID_v2017_08 "Drer\rab31, Drer\rab5ab, Drer\rab20, Drer\rab5b, Drer\rab5aa, Drer\rab24, Drer\rab22a, Drer\rab5c, Drer\zgc:154045" "Scer\YPT53, Scer\YPT52, Scer\VPS21, Scer\YPT10" "Cele\rab-5, Cele\C56E6.2, Cele\rab-21" "Xtro\rab5c, Xtro\rab20, Xtro\rab24, Xtro\rab5b, Xtro\rab21, Xtro\mras, Xtro\rab5a, Xtro\rab22a" "Mmus\Rab20, Mmus\Rab31, Mmus\Rab24, Mmus\Rab32, Mmus\Rab21, Mmus\Rab17, Mmus\Rab22a, Mmus\Rab5c, Mmus\Rab5a, Mmus\Rab5b" "Hsap\RAB20, Hsap\RAB31, Hsap\RAB5C, Hsap\RAB22A, Hsap\RAB32, Hsap\RAB21, Hsap\RAB5A, Hsap\RAB24, Hsap\RAB5B, Hsap\RAB17" "lethal,recessive" "chordotonal organ,lateral,ventral,external sensory organ,multidendritic neuron" FBgn0060635 l(3)S084512b lethal (3) S084512b http://flybase.org/reports/FBgn0060635 gene - - - "0845/12, l(3)S084512b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage" FBgn0036931 CG14183 - http://flybase.org/reports/FBgn0036931 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 - - CG14183 "IPR000048:IQ motif, EF-hand binding site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003959:ATPase, AAA-type, core" CG14183 11-Aug-17 DroID_v2017_08 "Drer\fign, Drer\iqca1, Drer\fignl1, Drer\spast, Drer\si:dkey-157g16.6, Drer\zgc:153738" "Scer\YTA6, Scer\SAP1" - "Xtro\fignl1, Xtro\fign, Xtro\spast" "Mmus\Fignl1, Mmus\Fignl2, Mmus\Spast, Mmus\Iqca, Mmus\Fign, Mmus\4931409K22Rik" "Hsap\SPAST, Hsap\FIGNL1, Hsap\IQCA1, Hsap\FIGN, Hsap\IQCA1L" viable FBgn0011216 disd dispersed at 46C http://flybase.org/reports/FBgn0011216 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - disd - - 11-Aug-17 DroID_v2017_08 - - - - - - male semi-sterile spermatid & nucleus FBgn0015499 l(3)65CEc lethal (3) 65CEc http://flybase.org/reports/FBgn0015499 - gene - - - "XII, l(3)65CEc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065920 l(2)SH0155 lethal (2) SH0155 http://flybase.org/reports/FBgn0065920 gene - - - "l(2)SH0155, l(2)SH2 0155" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267576 CR45916 - http://flybase.org/reports/FBgn0267576 non_protein_coding_gene - - - "CR45916, pri-mir-9a" - CR45916 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015894 su(Ubx[bx-1]) su(Ubx[bx-1]) http://flybase.org/reports/FBgn0015894 - gene - - - "anon-85AB, su(Ubx[bx-1])" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051681 CG31681 - http://flybase.org/reports/FBgn0051681 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 CG31681 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG31681 11-Aug-17 DroID_v2017_08 - - "Cele\rab-11.1, Cele\try-1" - "Mmus\4930519F16Rik, Mmus\Prss55, Mmus\Prss36, Mmus\Prss53, Mmus\Tmprss4" "Hsap\PRSS45, Hsap\TMPRSS4, Hsap\PRSS36, Hsap\PRSS53" viable FBgn0005744 l(1)TK236 lethal (1) TK236 http://flybase.org/reports/FBgn0005744 - gene - - - "l236, l(1)TK236" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0259192 CG42296 - http://flybase.org/reports/FBgn0259192 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG42296, CG15378" IPR002557:Chitin binding domain CG42296 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell DRSC00394 E -0.0177916 0.429054985 0.236141796 1.634882326 0.239216821 -0.30082429 FBgn0031463 G6P Glucose-6-Phosphatase http://flybase.org/reports/FBgn0031463 protein_coding_gene glucose-6-phosphatase activity ; GO:0004346 | inferred from biological aspect of ancestor with PANTHER:PTN000287473 glucose 6-phosphate metabolic process ; GO:0051156 | inferred from biological aspect of ancestor with PANTHER:PTN000287473 gluconeogenesis ; GO:0006094 | inferred from biological aspect of ancestor with PANTHER:PTN000287473 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000287473 "CG15400, G6pase, G6P" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG15400 11-Aug-17 DroID_v2017_08 "Drer\g6pca.2, Drer\g6pca.1, Drer\g6pcb, Drer\g6pc3" - - "Xtro\g6pc, Xtro\g6pc2" "Mmus\G6pc3, Mmus\G6pc, Mmus\G6pc2" "Hsap\G6PC3, Hsap\G6PC, Hsap\G6PC2" viable FBgn0015997 l(3)100CDa lethal (3) 100CDa http://flybase.org/reports/FBgn0015997 - gene - - - l(3)100CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052247 CG32247 - http://flybase.org/reports/FBgn0052247 protein_coding_gene - - - CG32247 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038262 CG14857 - http://flybase.org/reports/FBgn0038262 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG14857 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG14857 11-Aug-17 DroID_v2017_08 "Drer\slc22a7b.1, Drer\zmp:0000001102, Drer\slc22a13, Drer\oatx, Drer\slc22a21, Drer\slc22a5, Drer\zgc:175176, Drer\slc22a7b.2, Drer\sv2, Drer\LOC100334012, Drer\LOC101884074, Drer\slc22a7b.3, Drer\slc22a6l" "Scer\FLR1, Scer\HXT9, Scer\AQR1, Scer\QDR1, Scer\DTR1, Scer\YHK8, Scer\PHO84, Scer\TPO3, Scer\QDR3, Scer\TPO1, Scer\HXT2, Scer\TPO2, Scer\GIT1, Scer\QDR2" "Cele\C53B4.1, Cele\C06H5.6, Cele\ZK892.3, Cele\B0252.3, Cele\oct-1, Cele\Y66D12A.13, Cele\Y51A2D.18, Cele\C46C2.2, Cele\T22F7.1, Cele\B0361.11, Cele\Y57G11C.23" Xtro\slc22a6 "Mmus\Slc22a7, Mmus\Slc22a20, Mmus\Slc22a6, Mmus\Slc22a8, Mmus\Svop, Mmus\Slc22a2, Mmus\Slc22a14, Mmus\Slc22a26, Mmus\Slc22a4, Mmus\Slc22a5, Mmus\Slc22a29, Mmus\Slc22a28, Mmus\Slc22a21, Mmus\Slc22a22, Mmus\Sv2c, Mmus\Slc22a23, Mmus\Slc22a16, Mmus\Slc22a19, Mmus\Slc22a27, Mmus\Slc22a30" "Hsap\SLC22A8, Hsap\SLC22A10, Hsap\SVOP, Hsap\SLC22A1, Hsap\SLC22A5, Hsap\SLC22A24, Hsap\SLC22A11, Hsap\SLC22A4, Hsap\SLC22A7, Hsap\SLC22A12, Hsap\SV2C, Hsap\SLC22A2, Hsap\SLC22A9, Hsap\SLC22A25, Hsap\SLC22A23, Hsap\SLC22A6, Hsap\SV2B" FBgn0267987 CR46254 - http://flybase.org/reports/FBgn0267987 non_protein_coding_gene - - - CR46254 - CR46254 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261503 CR42651 - http://flybase.org/reports/FBgn0261503 non_protein_coding_gene - - - "CG42651, CR42651, pri-mir-10" - CR42651 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027216 l(1)G0329 lethal (1) G0329 http://flybase.org/reports/FBgn0027216 - gene - - - l(1)G0329 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001409 l(1)3Bd lethal (1) 3Bd http://flybase.org/reports/FBgn0001409 - gene - - - "zw-7, l(1)zw7, zw7, ZW-7, l(1)3Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,germline clone,cell lethal,lethal - all die before end of P-stage,some die during pharate adult stage" "female reproductive system,egg,germline clone" FBgn0051874 CG31874 - http://flybase.org/reports/FBgn0051874 protein_coding_gene fumarate hydratase activity ; GO:0004333 | inferred from electronic annotation with InterPro:IPR005677 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 fumarate metabolic process ; GO:0006106 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle enzyme complex ; GO:0045239 | inferred from electronic annotation with InterPro:IPR005677 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000154501 "NEST:bs10e11, CG31874" "IPR000362:Fumarate lyase family, IPR008948:L-Aspartase-like, IPR024083:Fumarase/histidase, N-terminal, IPR018951:Fumarase C, C-terminal, IPR020557:Fumarate lyase, conserved site, IPR022761:Fumarate lyase, N-terminal, IPR005677:Fumarate hydratase, class II" CG31874 11-Aug-17 DroID_v2017_08 "Drer\LOC100535417, Drer\fh" Scer\FUM1 Cele\fum-1 - Mmus\Fh1 Hsap\FH viable FBgn0002250 l(3)68Eb lethal (3) 68Eb http://flybase.org/reports/FBgn0002250 - gene - - - "rsg12, l(3)rsg12, l(3)68Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000956 fs(2)E3 female sterile (2) E3 http://flybase.org/reports/FBgn0000956 - gene - - - "fs2.3, fs(2)E3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,visible" "wing,female reproductive system" FBgn0036706 ND-24L NADH dehydrogenase (ubiquinone) 24 kDa subunit-like http://flybase.org/reports/FBgn0036706 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from biological aspect of ancestor with PANTHER:PTN000042665 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P19404 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from biological aspect of ancestor with PANTHER:PTN000042666 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P19404" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P19404 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000042666 "CG6485, NUHM, ND-24L" "IPR002023:NADH-quinone oxidoreductase subunit E-like, IPR012336:Thioredoxin-like fold" CG6485 11-Aug-17 DroID_v2017_08 Drer\ndufv2 - Cele\F53F4.10 Xtro\ndufv2 Mmus\Ndufv2 Hsap\NDUFV2 viable FBgn0028424 JhI-26 Juvenile hormone-inducible protein 26 http://flybase.org/reports/FBgn0028424 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG3767, JhI-26" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG3767 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025168 l(2)38EFc lethal (2) 38EFc http://flybase.org/reports/FBgn0025168 - gene - - - l(2)38EFc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266325 CR44990 - http://flybase.org/reports/FBgn0266325 non_protein_coding_gene - - - CR44990 - CR44990 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002355 l(3)87Eb lethal (3) 87Eb http://flybase.org/reports/FBgn0002355 - gene - - - "B16, B16-1, l(3)B16-1, l(3)B16, l(3)87Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0041629 Hexo2 Hexosaminidase 2 http://flybase.org/reports/FBgn0041629 protein_coding_gene beta-N-acetylglucosaminidase activity ; GO:0016231 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR013781, InterPro:IPR015883 negative regulation of growth of symbiont in host ; GO:0044130 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" plasma membrane ; GO:0005886 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "HEX2, HEX 2, DmHex2, CG1787, Hexo2, HEXO2" "IPR025705:Beta-hexosaminidase, IPR015883:Glycoside hydrolase family 20, catalytic domain, IPR017853:Glycoside hydrolase superfamily, IPR029018:Chitobiase/beta-hexosaminidase domain 2-like, IPR029019:Beta-hexosaminidase, eukaryotic type, N-terminal" CG1787 11-Aug-17 DroID_v2017_08 "Drer\hexb, Drer\hexa" - Cele\hex-1 Xtro\hexb "Mmus\Hexb, Mmus\Hexa" "Hsap\HEXA, Hsap\HEXB" "viable,fertile" FBgn0032261 CG6094 - http://flybase.org/reports/FBgn0032261 protein_coding_gene "translation release factor activity, codon nonspecific ; GO:0016150 | inferred from sequence or structural similarity with UniProtKB:Q14197" mitochondrial translational termination ; GO:0070126 | inferred from sequence or structural similarity with UniProtKB:Q14197 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q14197 "CG6094, FBgn 32261, dICT1" IPR000352:Peptide chain release factor class I/class II CG6094 11-Aug-17 DroID_v2017_08 Drer\ict1 Scer\PTH4 Cele\R02F2.9 Xtro\ict1 Mmus\Mrpl58 Hsap\MRPL58 "viable,visible" trichogen cell FBgn0027153 l(3)61Db lethal (3) 61Db http://flybase.org/reports/FBgn0027153 - gene - - - l(3)61Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000364 Cpt Clipt http://flybase.org/reports/FBgn0000364 - gene - - - "Cpt, CPTI" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,lethal,recessive" macrochaeta FBgn0086350 tef teflon http://flybase.org/reports/FBgn0086350 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 male meiosis chromosome separation ; GO:0051308 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype male meiosis I ; GO:0007141 | inferred from mutant phenotype autosome ; GO:0030849 | inferred from direct assay "tef, CG8961, l(2)k15914" IPR013087:Zinc finger C2H2-type CG8961 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028285 l(1)G0411 lethal (1) G0411 http://flybase.org/reports/FBgn0028285 gene - - - l(1)G0411 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,male,female,recessive" FBgn0265559 21.28 - http://flybase.org/reports/FBgn0265559 gene - - - 21.28 - - 11-Aug-17 DroID_v2017_08 - - - - - - learning defective FBgn0011602 IM137 IM137 http://flybase.org/reports/FBgn0011602 - gene - - - IM137 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005115 l(1)2269 lethal (1) 2269 http://flybase.org/reports/FBgn0005115 - gene - - - l(1)2269 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,tumorigenic" imaginal disc FBgn0004651 Fs(2)M Female sterile of Meyer http://flybase.org/reports/FBgn0004651 "FBgn0000929, FBgn0000995" gene - - - "Fs, Fs(2)D-M, Fs(2)M" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,dominant,male fertile,visible" FBgn0000657 fin finer http://flybase.org/reports/FBgn0000657 - gene - - - fin - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male sterile,viable,male" macrochaeta FBgn0040571 CG17193 - http://flybase.org/reports/FBgn0040571 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE41733, CG17193" - CG17193 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033794 CG13326 - http://flybase.org/reports/FBgn0033794 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000593603 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000593603 CG13326 "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG13326 11-Aug-17 DroID_v2017_08 "Drer\ctnnd2b, Drer\armc4, Drer\jupb, Drer\pkp4, Drer\armc3, Drer\ctnnd2a, Drer\arvcfb" Scer\VAC8 "Cele\hmp-2, Cele\jac-1" "Xtro\ctnnb1, Xtro\armc3, Xtro\armc4" "Mmus\Ctnnd2, Mmus\Pkp4, Mmus\Arvcf, Mmus\Armc3, Mmus\Armc4, Mmus\Ctnnb1, Mmus\Jup" "Hsap\PKP4, Hsap\CTNNB1, Hsap\ARMC3, Hsap\JUP, Hsap\CTNND2, Hsap\ARVCF" viable FBgn0043532 Obp56i Odorant-binding protein 56i http://flybase.org/reports/FBgn0043532 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "56i, 56I, Obp-a, anon-AE003794.2, CG30448, Obp56i, DmelObp56i" IPR006170:Pheromone/general odorant binding protein CG30448 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0051925 CG31925 - http://flybase.org/reports/FBgn0051925 protein_coding_gene - - - CG31925 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082924 snoRNA:Or-aca2 snoRNA:Or-aca2 http://flybase.org/reports/FBgn0082924 snoRNA_gene - - - "snoRNA:Or-aca2, Or_aca2 snoRNA, DmOr_aca2 snoRNA, DmOr_aca2, CR34593, Or-aca2, snoRNA:Or-ACA2" - CR34593 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032601 yellow-b yellow-b http://flybase.org/reports/FBgn0032601 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG17914, yellow-b, yell-b, Yellow-b" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG17914 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\F49E11.8, Cele\T27A1.3, Cele\C24H12.1, Cele\fbxa-76" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 " embryonic stage , pupal stage , adult stage , larval stage " adult head

viable FBgn0069088 rpr::hid rpr::W http://flybase.org/reports/FBgn0069088 engineered_fusion_gene - - - "rpr::W, rpr::hid" - - 11-Aug-17 DroID_v2017_08 - - - - - - increased cell death FBgn0267572 CR45912 - http://flybase.org/reports/FBgn0267572 non_protein_coding_gene - - - CR45912 - CR45912 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010932 l(3)09070 lethal (3) 09070 http://flybase.org/reports/FBgn0010932 - gene - - - l(3)09070 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0030087 CG7766 - http://flybase.org/reports/FBgn0030087 protein_coding_gene calmodulin binding ; GO:0005516 | inferred from electronic annotation with InterPro:IPR008734 phosphorylase kinase activity ; GO:0004689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000844181 glycogen metabolic process ; GO:0005977 | inferred from electronic annotation with InterPro:IPR008734 phosphorylase kinase complex ; GO:0005964 | inferred from biological aspect of ancestor with PANTHER:PTN000844181 CG7766 "IPR008734:Phosphorylase kinase alpha/beta subunit, IPR008928:Six-hairpin glycosidase-like, IPR011613:Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family" CG7766 11-Aug-17 DroID_v2017_08 "Drer\phkb, Drer\phka2, Drer\phka1b, Drer\phka1a" - Cele\C14B9.8 "Xtro\phka2, Xtro\phkb, Xtro\LOC100498239" "Mmus\Phka1, Mmus\Phkb, Mmus\Phka2" "Hsap\PHKA1, Hsap\PHKB, Hsap\PHKA2" FBgn0032415 rho-6 rhomboid-6 http://flybase.org/reports/FBgn0032415 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001117493 "rho-6, Rho-related [33C1], CG17212, rho 6, rho6" "IPR002610:Peptidase S54, rhomboid, IPR017213:Peptidase S54, rhomboid, metazoan, IPR022764:Peptidase S54, rhomboid domain" CG17212 11-Aug-17 DroID_v2017_08 "Drer\rhbdl3, Drer\rhbdl1, Drer\rhbdl2" - "Cele\rom-2, Cele\rom-3, Cele\rom-1" Xtro\rhbdl2 "Mmus\Rhbdl3, Mmus\Rhbdl2, Mmus\Rhbdf1, Mmus\Rhbdl1" "Hsap\RHBDL1, Hsap\RHBDF1, Hsap\RHBDL2, Hsap\RHBDL3" viable FBgn0043994 Su(rst)D207 Su(rst)D207 http://flybase.org/reports/FBgn0043994 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D207, Su(rst)D207" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266966 CR45417 - http://flybase.org/reports/FBgn0266966 non_protein_coding_gene - - - CR45417 - CR45417 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005433 l(1)v3 lethal (1) v3 http://flybase.org/reports/FBgn0005433 - gene - - - "l(1)3, l(1)v3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016942 stich2 sticky ch2 http://flybase.org/reports/FBgn0016942 FBgn0011718 gene - peripheral nervous system development ; GO:0007422 | traceable author statement - "sticky ch1-2, sticky ch, stich2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" chordotonal organ FBgn0259869 Su(Ste):CR42438 Su(Ste):CR42438 http://flybase.org/reports/FBgn0259869 non_protein_coding_gene - - - "Su(Ste):CR42438, CR42438" - CR42438 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002616 M(3)69E Minute (3) 69E http://flybase.org/reports/FBgn0002616 - gene - - - "M[33d30], M(3)h, M(3)h[y], M(3L)h, Mh, M(3)y, M(3)v, M(3)6, M(3)33j, M(3)33d, M(3)69E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible,developmental rate defective,eye color defective" "macrochaeta,eye,wing,pigment cell,wing vein L2,posterior crossvein" FBgn0259406 C153 - http://flybase.org/reports/FBgn0259406 gene - - - C153 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin" FBgn0025747 l(3)95Az lethal (3) 95Az http://flybase.org/reports/FBgn0025747 - gene - - - l(3)95Az - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000969 fs(2)eo5 female sterile (2) eo5 http://flybase.org/reports/FBgn0000969 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "wp19, fs(2)eoWP19, fs(2)eo-G, fs(2)eo5" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0083311 E(smoDN)1414 Enhancer of smoDN 1414 http://flybase.org/reports/FBgn0083311 gene - - - E(smoDN)1414 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002406 l(3)99Dg lethal (3) 99Dg http://flybase.org/reports/FBgn0002406 - gene - - - l(3)99Dg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060925 l(3)S042205 lethal (3) S042205 http://flybase.org/reports/FBgn0060925 gene - - - "0422/05, l(3)S042205" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0060522 l(3)S102312b lethal (3) S102312b http://flybase.org/reports/FBgn0060522 gene - - - "1023/12, l(3)S102312b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061497 l(2)45Ap lethal (2) 45Ap http://flybase.org/reports/FBgn0061497 gene - - - l(2)45Ap - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266171 pre-mod(mdg4)-AB - http://flybase.org/reports/FBgn0266171 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-AB, CG44877" "IPR007588:Zinc finger, FLYWCH-type" CG44877 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Flywch2, Mmus\Flywch1" - FBgn0262765 Mst77Y-17Psi Male-specific pseudogene 77Y 17 http://flybase.org/reports/FBgn0262765 pseudogene_attribute - - - Mst77Y-17Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020811 mei-1223 mei-1223 http://flybase.org/reports/FBgn0020811 - gene - - - mei-1223 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" spermatid FBgn0266693 CR45183 - http://flybase.org/reports/FBgn0266693 non_protein_coding_gene - - - CR45183 - CR45183 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001833 l(1)ts504 lethal (1) ts504 http://flybase.org/reports/FBgn0001833 - gene - - - l(1)ts504 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" "adult head,adult thorax" FBgn0040588 CG13841 - http://flybase.org/reports/FBgn0040588 protein_coding_gene - - - CG13841 - CG13841 11-Aug-17 DroID_v2017_08 - - - - - - DRSC26257 K -0.710219897 -0.906539037 0.246235043 -0.343377375 -0.079942826 1.752175511 FBgn0265699 CR44506 - http://flybase.org/reports/FBgn0265699 non_protein_coding_gene - - - CR44506 - CR44506 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053491 CR33491 - http://flybase.org/reports/FBgn0053491 pseudogene_attribute - - - "CG33491, CR33491" - CR33491 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263745 CR43670 - http://flybase.org/reports/FBgn0263745 pseudogene_attribute - - - "CR43670, CG31782, BcDNA:GM06363" - CR43670 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264325 Atg6 Autophagy-related 6 http://flybase.org/reports/FBgn0264325 protein_coding_gene molecular_function ; GO:0003674 | no biological data available autophagy ; GO:0006914 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 late endosome to vacuole transport ; GO:0045324 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype cellular response to nitrogen starvation ; GO:0006995 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype inferred from genetic interaction with Pi3K59F hemopoiesis ; GO:0030097 | inferred from mutant phenotype glycophagy ; GO:0061723 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype inferred from genetic interaction with puc nucleophagy ; GO:0044804 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 protein secretion ; GO:0009306 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern cellular response to starvation ; GO:0009267 | inferred from mutant phenotype "phosphatidylinositol 3-kinase complex, class III, type I ; GO:0034271 | inferred from direct assay pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 cytoplasmic vesicle ; GO:0031410 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 phosphatidylinositol 3-kinase complex, class III, type II ; GO:0034272 | inferred from biological aspect of ancestor with PANTHER:PTN000298965" "Atg6, CG5429, l(3)00096, atg6, Beclin-1, DmAtg6, ATG6, Beclin1, beclin, dAtg6" IPR007243:Atg6/Beclin CG5429 11-Aug-17 DroID_v2017_08 Drer\becn1 Scer\VPS30 Cele\bec-1 Xtro\becn1 "Mmus\Becn2, Mmus\Becn1" "Hsap\BECN1, Hsap\BECN2" FBgn0026141 Cdlc2 Cytoplasmic dynein light chain 2 http://flybase.org/reports/FBgn0026141 FBgn0044766 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR001372, InterPro:IPR019763 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity" dynein complex ; GO:0030286 | inferred from electronic annotation with InterPro:IPR001372 dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG5450, dlc, anon-WO0140519.117, Cdlc2, Cdcl2" "IPR001372:Dynein light chain, type 1/2, IPR019763:Dynein light chain, type 1/2, conserved site" CG5450 11-Aug-17 DroID_v2017_08 "Drer\dnal4b, Drer\dynll2b, Drer\dynll1, Drer\dnal4a, Drer\dynll2a" Scer\DYN2 "Cele\dlc-1, Cele\dlc-2, Cele\dlc-5" "Xtro\dynll1, Xtro\dynll2, Xtro\dnal4" "Mmus\BC048507, Mmus\Dynll2, Mmus\Dnal4, Mmus\Dynll1" "Hsap\DYNLL2, Hsap\DYNLL1, Hsap\DNAL4" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0034128 CG4409 - http://flybase.org/reports/FBgn0034128 protein_coding_gene - - - CG4409 IPR010629:Insect allergen-related CG4409 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001766 l(1)M26 lethal (1) M26 http://flybase.org/reports/FBgn0001766 - gene - - - l(1)M26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0029724 CG15472 - http://flybase.org/reports/FBgn0029724 protein_coding_gene - - - CG15472 IPR031732:Protein of unknown function DUF4729 CG15472 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030136 RpS28b Ribosomal protein S28b http://flybase.org/reports/FBgn0030136 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000005693 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000289 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022627 maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with SGD:S000005693 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "RpS28b, CG2998, RS28_DROME" "IPR000289:Ribosomal protein S28e, IPR012340:Nucleic acid-binding, OB-fold, IPR028626:Ribosomal protein S28e conserved site" CG2998 11-Aug-17 DroID_v2017_08 Drer\rps28 "Scer\RPS28B, Scer\RPS28A" Cele\rps-28 Xtro\rps28p9 Mmus\Rps28 Hsap\RPS28 lethal DRSC18258 EK -0.142827143 -1.045384294 0.280846002 -1.758446591 1.554184109 3.1699096 FBgn0267493 Mst77Y-9 Male-specific transcript 77Y 9 http://flybase.org/reports/FBgn0267493 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F "Mst77Y-9, CG45769, MST77Y" - CG45769 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021433 Dl::Ser Dl::Ser http://flybase.org/reports/FBgn0021433 - engineered_fusion_gene - - - Dl::Ser - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective" "macrochaeta & thorax | supernumerary-537.4,ommatidium & eye disch-H10,photoreceptor cell R8 & eye disch-H10,macrochaeta & thorax | supernumerary | somatic clone | cell autonomousUbx.PdC,eye" FBgn0028050 l(3)S096108 lethal (3) S096108 http://flybase.org/reports/FBgn0028050 gene - - - "0961/08, l(3)S096108" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0064171 l(3)201.51 lethal (3) 201.51 http://flybase.org/reports/FBgn0064171 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available l(3)201.51 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003539 Str Stretched wings http://flybase.org/reports/FBgn0003539 - gene - - - Str - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" wing FBgn0016029 l(3)89El lethal (3) 89El http://flybase.org/reports/FBgn0016029 - gene - - - "l(3)M171, l(3)89El" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263536 mir-4974 mir-4974 stem loop http://flybase.org/reports/FBgn0263536 miRNA_gene - - - "mir-4974, dme-mir-4974, CR43521" - CR43521 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263964 BG01976 - http://flybase.org/reports/FBgn0263964 gene - - - BG01976 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,female limited,short lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0065752 l(2)SH0496 lethal (2) SH0496 http://flybase.org/reports/FBgn0065752 gene - - - "l(2)SH0496, l(2)SH2 0496" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052334 CG32334 - http://flybase.org/reports/FBgn0052334 protein_coding_gene - - - CG32334 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035254 CG7974 - http://flybase.org/reports/FBgn0035254 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:24932 CG7974 IPR010756:Hepatocellular carcinoma-associated antigen 59 CG7974 11-Aug-17 DroID_v2017_08 Drer\zgc:103692 - "Cele\T23G11.4, Cele\M151.4" Xtro\c9orf78 Mmus\BC005624 Hsap\C9orf78 viable FBgn0031939 CG13796 - http://flybase.org/reports/FBgn0031939 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT neurotransmitter transport ; GO:0006836 | inferred from sequence model transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model "CT42497, CG18590, CG13796, CG13796-PA" IPR000175:Sodium:neurotransmitter symporter CG13796 11-Aug-17 DroID_v2017_08 "Drer\slc6a4b, Drer\slc6a5, Drer\slc6a2, Drer\slc6a6a, Drer\slc6a9, Drer\slc6a1b, Drer\slc6a13, Drer\slc6a16a, Drer\slc6a1a, Drer\slc6a19a.2, Drer\slc6a18, Drer\slc6a1l, Drer\slc6a19a.1, Drer\si:ch211-117c9.5, Drer\slc6a8, Drer\slc6a17, Drer\slc6a15, Drer\slc6a4a, Drer\zgc:158225, Drer\slc6a14, Drer\slc6a19b" - Cele\snf-6 "Xtro\slc6a8, Xtro\slc6a14.2, Xtro\slc6a12, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a15, Xtro\LOC100127682, Xtro\slc6a16, Xtro\slc6a3, Xtro\slc6a9, Xtro\slc6a5, Xtro\slc6a17, Xtro\slc6a7, Xtro\slc6a2, Xtro\slc6a19, Xtro\slc6a1" "Mmus\Slc6a3, Mmus\Slc6a21, Mmus\Slc6a1, Mmus\Slc6a15, Mmus\Slc6a12, Mmus\Slc6a8, Mmus\Slc6a20b, Mmus\Slc6a16, Mmus\Slc6a13, Mmus\Slc6a2, Mmus\Slc6a7, Mmus\Slc6a20a, Mmus\Slc6a9, Mmus\Slc6a18, Mmus\Slc6a11, Mmus\Slc6a4, Mmus\Slc6a19, Mmus\Slc6a5, Mmus\Slc6a6, Mmus\Slc6a17, Mmus\Slc6a14" "Hsap\SLC6A17, Hsap\SLC6A1, Hsap\SLC6A2, Hsap\SLC6A13, Hsap\SLC6A14, Hsap\SLC6A18, Hsap\SLC6A7, Hsap\SLC6A8, Hsap\SLC6A15, Hsap\SLC6A5, Hsap\SLC6A12, Hsap\SLC6A9, Hsap\SLC6A4, Hsap\SLC6A3, Hsap\SLC6A19, Hsap\SLC6A6, Hsap\SLC6A16, Hsap\SLC6A11, Hsap\SLC6A20" "viable,planar polarity defective" FBgn0022327 l(1)A27.2 lethal (1) A27.2 http://flybase.org/reports/FBgn0022327 - gene - - - "A27.2, l(1)A27.2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020339 anon-5Cc anon-5Cc http://flybase.org/reports/FBgn0020339 - gene - - - anon-5Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264713 CR43981 - http://flybase.org/reports/FBgn0264713 non_protein_coding_gene - - - CR43981 - CR43981 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082190 l(3)S006603 lethal (3) S006603 http://flybase.org/reports/FBgn0082190 gene - - - l(3)S006603 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0037664 CG8420 - http://flybase.org/reports/FBgn0037664 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "anon-WO0140519.182, CG8420" - CG8420 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035932 CG13308 - http://flybase.org/reports/FBgn0035932 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG13308 IPR002557:Chitin binding domain CG13308 11-Aug-17 DroID_v2017_08 - - Cele\ZC84.1 - - - viable FBgn0052761 tRNA:Glu-CTC-6-1Psi transfer RNA:Glutamic acid-CTC 6-1 pseudogene http://flybase.org/reports/FBgn0052761 pseudogene_attribute - - - "AE002566.trna3-GluCTC, tRNA:EPsi:CTC:AE002566, CR32761, chrX.trna3-GluCTC, tRNA:Glu-CTC-6-1Psi, tRNA:CR32761:Psi, tRNA-Glu-CTC-6-1" - CR32761 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010764 l(3)01949 lethal (3) 01949 http://flybase.org/reports/FBgn0010764 - gene - - - l(3)01949 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0034179 CG6805 - http://flybase.org/reports/FBgn0034179 protein_coding_gene inositol trisphosphate phosphatase activity ; GO:0046030 | non-traceable author statement phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from electronic annotation with InterPro:IPR000300 dephosphorylation ; GO:0016311 | non-traceable author statement - "IPP, CK01299, BEST:CK01299, CG6805" "IPR000300:Inositol polyphosphate-related phosphatase, IPR005135:Endonuclease/exonuclease/phosphatase" CG6805 11-Aug-17 DroID_v2017_08 "Drer\inpp5jb, Drer\inpp5j, Drer\inppl1b, Drer\inpp5b, Drer\inpp5kb, Drer\inpp5e, Drer\inppl1a, Drer\ocrl, Drer\inpp5d, Drer\sh2d1aa, Drer\inpp5ka" "Scer\INP51, Scer\INP54, Scer\INP53, Scer\INP52" Cele\cil-1 "Xtro\inpp5b, Xtro\inpp5d, Xtro\inpp5k, Xtro\sec16a, Xtro\inpp5j" "Mmus\Sh2d1b2, Mmus\Sh2d1a, Mmus\Inpp5j, Mmus\Inpp5d, Mmus\Inpp5k, Mmus\Inpp5e, Mmus\Ocrl, Mmus\Sh2d1b1, Mmus\Inppl1, Mmus\Inpp5b" "Hsap\SH2D1B, Hsap\INPP5K, Hsap\INPP5J, Hsap\INPP5D, Hsap\INPP5B, Hsap\OCRL, Hsap\INPP5E, Hsap\INPPL1" "viable,fertile" FBgn0033135 Tsp42En Tetraspanin 42En http://flybase.org/reports/FBgn0033135 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG12839, Dm.Tsp42En, BcDNA:RH02160, Tsp42En" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12839 11-Aug-17 DroID_v2017_08 "Drer\cd63, Drer\tspan33b, Drer\tspan33a, Drer\zgc:113223" - "Cele\tsp-16, Cele\tsp-7, Cele\tsp-5" - "Mmus\Cd63, Mmus\Tspan32, Mmus\Tspan33" "Hsap\TSPAN32, Hsap\TSPAN15, Hsap\TSPAN33, Hsap\CD63" viable FBgn0050022 CG30022 - http://flybase.org/reports/FBgn0050022 protein_coding_gene iron ion binding ; GO:0005506 | inferred from sequence or structural similarity with HGNC:23287 glutathione metabolic process ; GO:0006749 | inferred from sequence or structural similarity with HGNC:23287 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:23287 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:23287 "CG9026, BcDNA:RE56416, CG30022" IPR001279:Metallo-beta-lactamase CG30022 11-Aug-17 DroID_v2017_08 Drer\ethe1 "Scer\GLO2, Scer\GLO4" Cele\ethe-1 Xtro\ethe1 Mmus\Ethe1 Hsap\ETHE1 viable FBgn0086673 CG13272 - http://flybase.org/reports/FBgn0086673 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13272, CG33312" IPR015943:WD40/YVTN repeat-like-containing domain CG13272 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019778 l(1)31 lethal (1) 31 http://flybase.org/reports/FBgn0019778 - gene - - - l(1)31 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013238 E(var)2 E(var)2 http://flybase.org/reports/FBgn0013238 - gene - - - E(var)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0004205 l(3)84Ec lethal (3) 84Ec http://flybase.org/reports/FBgn0004205 - gene - - - l(3)84Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065786 l(2)SH0435 lethal (2) SH0435 http://flybase.org/reports/FBgn0065786 gene - - - "l(2)SH0435, l(2)SH2 0435" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051833 CG31833 - http://flybase.org/reports/FBgn0051833 protein_coding_gene - - - CG31833 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085828 CR42195 - http://flybase.org/reports/FBgn0085828 rRNA_gene - - - CR42195 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011534 l(3)00707 lethal (3) 00707 http://flybase.org/reports/FBgn0011534 - gene - - - l(3)00707 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005072 fs(2)OW213 female sterile (2) OW213 http://flybase.org/reports/FBgn0005072 - gene - - - fs(2)OW213 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030215 CG15296 - http://flybase.org/reports/FBgn0030215 protein_coding_gene - - - "BcDNA:AT26906, CG15296" IPR026769:MICOS complex subunit Mic13 CG15296 11-Aug-17 DroID_v2017_08 - - - - - Hsap\C19orf70 "fertile,viable" FBgn0034275 CG5002 - http://flybase.org/reports/FBgn0034275 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 CG5002 "IPR002645:STAS domain, IPR011547:SLC26A/SulP transporter domain, IPR001902:SLC26A/SulP transporter" CG5002 11-Aug-17 DroID_v2017_08 "Drer\slc26a2, Drer\slc26a10, Drer\slc26a1, Drer\slc26a6, Drer\si:ch211-117c9.2, Drer\slc26a3.2, Drer\slc26a11, Drer\slc26a3.1, Drer\slc26a6l, Drer\slc26a5, Drer\slc26a4" "Scer\YPR003C, Scer\YGR125W, Scer\SUL1, Scer\SUL2" "Cele\sulp-4, Cele\sulp-6, Cele\sulp-5, Cele\sulp-8, Cele\sulp-1, Cele\sulp-2, Cele\sulp-3, Cele\sulp-7" "Xtro\slc26a4, Xtro\slc26a7, Xtro\slc26a10, Xtro\slc26a1, Xtro\slc26a9, Xtro\slc26a11, Xtro\slc26a5, Xtro\slc26a2, Xtro\slc26a6" "Mmus\Slc26a9, Mmus\Slc26a7, Mmus\Slc26a8, Mmus\Slc26a6, Mmus\Slc26a5, Mmus\Slc26a4, Mmus\Slc26a10, Mmus\Slc26a3, Mmus\Slc26a2, Mmus\Slc26a11, Mmus\Slc26a1" "Hsap\SLC26A11, Hsap\SLC26A4, Hsap\SLC26A9, Hsap\SLC26A6, Hsap\SLC26A5, Hsap\SLC26A8, Hsap\SLC26A3, Hsap\SLC26A1, Hsap\SLC26A7, Hsap\SLC26A2, Hsap\SLC26A10" viable FBgn0016660 H15 H15 http://flybase.org/reports/FBgn0016660 - protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR002070, InterPro:IPR008967, InterPro:IPR018186" neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay cardioblast cell fate commitment ; GO:0042684 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype heart process ; GO:0003015 | inferred from direct assay leg disc pattern formation ; GO:0035223 | inferred from genetic interaction with mid regulation of cell fate specification ; GO:0042659 | inferred from genetic interaction with mid chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR002070, InterPro:IPR018186" "Nmr-1, CG6604, nmr1, H15, Dm-H15, nmr, dm-H15, Nmr, nmr[H15], Tbx20" "IPR018186:Transcription factor, T-box, conserved site, IPR001699:Transcription factor, T-box, IPR002070:Transcription factor, Brachyury, IPR008967:p53-like transcription factor, DNA-binding" CG6604 11-Aug-17 DroID_v2017_08 "Drer\tbx5b, Drer\tbx15, Drer\tbx1, Drer\eomesa, Drer\tbx16, Drer\eomesb, Drer\tbx5a, Drer\tbx2b, Drer\tbx20, Drer\tbr1b, Drer\tbr1a, Drer\grap2b, Drer\mgaa, Drer\tbx3b, Drer\tbx2a, Drer\tbx22, Drer\tbx18, Drer\tbx21, Drer\tbx6" - "Cele\mls-1, Cele\tbx-2, Cele\tbx-7, Cele\tbx-43, Cele\mab-9" "Xtro\tbx20, Xtro\tbx4, Xtro\tbx3, Xtro\tbx18, Xtro\tbx5, Xtro\tbx22, Xtro\tbx2, Xtro\tbx1, Xtro\tbx15, Xtro\vegt, Xtro\mga" "Mmus\Tbx22, Mmus\Tbx20, Mmus\Tbx4, Mmus\Tbx18, Mmus\Tbx5, Mmus\Tbx3, Mmus\Mga, Mmus\Tbr1, Mmus\Tbx15, Mmus\Tbx1, Mmus\Tbx2, Mmus\Tbx21, Mmus\Tbx6, Mmus\Tbx10, Mmus\Eomes" "Hsap\TBX20, Hsap\TBX2, Hsap\TBX1, Hsap\TBR1, Hsap\TBX4, Hsap\TBX15, Hsap\MGA, Hsap\TBX18, Hsap\TBX3, Hsap\TBX22, Hsap\TBX10, Hsap\TBX5, Hsap\EOMES, Hsap\TBX21, Hsap\TBX6" "viable,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal appendage,somatic clone,embryonic/larval neuroblast,ganglion mother cell" FBgn0021944 Coprox Coproporphyrinogen oxidase http://flybase.org/reports/FBgn0021944 "FBgn0021932, FBgn0027909" protein_coding_gene coproporphyrinogen oxidase activity ; GO:0004109 | inferred from sequence or structural similarity coproporphyrinogen oxidase activity ; GO:0004109 | inferred from sequence or structural similarity with UniProtKB:P36551 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with UniProtKB:P36551 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001260, InterPro:IPR018375 heme biosynthetic process ; GO:0006783 | inferred from sequence or structural similarity with UniProtKB:P36551" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P36551 "l(2)k10617, l(2)k11018, CG3433, BcDNA:GM14838, Coprox" "IPR001260:Coproporphyrinogen III oxidase, aerobic, IPR018375:Coproporphyrinogen III oxidase, conserved site" CG3433 11-Aug-17 DroID_v2017_08 Drer\cpox Scer\HEM13 - Xtro\cpox Mmus\Cpox Hsap\CPOX "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,locomotor rhythm defective" FBgn0039128 CG13599 - http://flybase.org/reports/FBgn0039128 protein_coding_gene - regulation of exit from mitosis ; GO:0007096 | inferred from electronic annotation with InterPro:IPR009511 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR009511 CG13599 IPR009511:Mad1/Cdc20-bound-Mad2 binding protein CG13599 11-Aug-17 DroID_v2017_08 Drer\mad2l1bp - - - Mmus\Mad2l1bp Hsap\MAD2L1BP "viable,fertile,visible" trichogen cell FBgn0032221 Schip1 Schwannomin interacting protein 1 http://flybase.org/reports/FBgn0032221 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q0KHQ5 positive regulation of protein serine/threonine kinase activity ; GO:0071902 | inferred from mutant phenotype positive regulation of hippo signaling ; GO:0035332 | inferred from mutant phenotype hippo signaling ; GO:0035329 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype adherens junction ; GO:0005912 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "CG5375, Schip1" IPR015649:Schwannomin interacting protein 1 CG5375 11-Aug-17 DroID_v2017_08 "Drer\zgc:153615, Drer\schip1" - Cele\F35H12.1 Xtro\schip1 "Mmus\Schip1, Mmus\Gm21949" "Hsap\SCHIP1, Hsap\IQCJ-SCHIP1" viable FBgn0040589 CG13839 - http://flybase.org/reports/FBgn0040589 protein_coding_gene - - - CG13839 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029054 l(1)G0453 lethal (1) G0453 http://flybase.org/reports/FBgn0029054 gene - - - l(1)G0453 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0012027 tRNA:Tyr-GTA-1-5 transfer RNA:Tyrosine-GTA 1-5 http://flybase.org/reports/FBgn0012027 "FBgn0003849, FBgn0012014, FBgn0051552, FBgn0060002" tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "Tyr-tRNA, tRNA-Tyr, 85Ad, tRNA[Tyr][[1gamma]], AE002708.trna60-TyrGTA, tRNA:Y, tRNA:Y:GTA:AE002708-d, CR31552, tRNA:tyr1:85Ad, tRNA[Tyr], chr3R.trna66-TyrGTA, tRNA-Tyr-GTA-1-5, tRNA:Tyr-GTA-1-5, tRNA:Y1:85Ad, UAC" - CR31552 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069299 ali alice http://flybase.org/reports/FBgn0069299 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available ali - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "filzkorper,ectopic,germline clone,maternal effect" FBgn0043588 EK3-3 EK3-3 http://flybase.org/reports/FBgn0043588 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available EK3-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "eye,wing vein" FBgn0267593 CR45931 - http://flybase.org/reports/FBgn0267593 pseudogene_attribute - - - "CR45931, CG40245" - CR45931 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044446 EP851 EP851 http://flybase.org/reports/FBgn0044446 gene - - - EP851 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0031771 ND-51 NADH dehydrogenase (ubiquinone) 51 kDa subunit http://flybase.org/reports/FBgn0031771 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR001949 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR011537 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR001949, InterPro:IPR011537, InterPro:IPR019575 FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR001949, InterPro:IPR011537 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P49821" "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P49821" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P49821 "CG9140, NUBM, ND-51, ND51" "IPR001949:NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site, IPR011537:NADH ubiquinone oxidoreductase, F subunit, IPR011538:NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain, IPR019554:Soluble ligand binding domain, IPR019575:NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain" CG9140 11-Aug-17 DroID_v2017_08 "Drer\ndufv1, Drer\zgc:123290" - Cele\nuo-1 Xtro\ndufv1 Mmus\Ndufv1 Hsap\NDUFV1 "lethal,RU486 conditional,developmental rate defective,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266096 CR44833 - http://flybase.org/reports/FBgn0266096 non_protein_coding_gene - - - "CR44833, Mgn94020" - CR44833 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086266 Vm26Ac Vitelline membrane 26Aac http://flybase.org/reports/FBgn0086266 protein_coding_gene structural constituent of vitelline membrane ; GO:0008316 | inferred from sequence model vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from sequence model egg coat ; GO:0035805 | inferred from sequence model chorion ; GO:0042600 | inferred from direct assay "CG13997, TU-3, fc20, Vm26Ac, Fcp26Ac, fc 20, VM26Ac" IPR013135:Vitelline membrane cysteine-rich domain CG13997 11-Aug-17 DroID_v2017_08 - Scer\NUP159 - - - - oogenesis stage | stage S8-11 FBgn0266795 CR45257 - http://flybase.org/reports/FBgn0266795 non_protein_coding_gene - - - CR45257 - CR45257 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259426 EP-1152.1 - http://flybase.org/reports/FBgn0259426 gene - - - EP-1152.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing" FBgn0085739 CR40507 - http://flybase.org/reports/FBgn0085739 rRNA_gene - - - CR40507 - CR40507 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044082 E(rst)H253 E(rst)H253 http://flybase.org/reports/FBgn0044082 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H253, E(rst)H253" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039023 CG4723 - http://flybase.org/reports/FBgn0039023 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG4723 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG4723 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\ece2b, Drer\mmel1, Drer\phex" - "Cele\nep-12, Cele\nep-10, Cele\nep-23, Cele\nep-3, Cele\nep-24, Cele\nep-5, Cele\nep-8, Cele\nep-18, Cele\nep-20, Cele\nep-9, Cele\nep-7, Cele\nep-16, Cele\nep-26, Cele\nep-17, Cele\nep-13, Cele\nep-21, Cele\nep-19, Cele\nep-6" "Xtro\mmel1, Xtro\ecel1, Xtro\ece2, Xtro\ece1" "Mmus\Mmel1, Mmus\Ecel1, Mmus\Phex, Mmus\Ece2, Mmus\Kel, Mmus\Ece1, Mmus\Mme" "Hsap\ECE2, Hsap\KEL, Hsap\MMEL1, Hsap\PHEX, Hsap\MME, Hsap\ECEL1, Hsap\ECE1" viable FBgn0051603 tRNA:Asp-GTC-1-5 transfer RNA:Aspartic acid-GTC 1-5 http://flybase.org/reports/FBgn0051603 tRNA_gene - - - "tRNA:asp2:29E, tRNA:D2:29E, CR31603, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna13-AspGTC, tRNA:Asp-GTC-1-5, tRNA:CR31603, tRNA-Asp-GTC-1-5, GAC" - CR31603 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052115 CG32115 - http://flybase.org/reports/FBgn0052115 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE40923, CG32115" "IPR032675:Leucine-rich repeat domain, L domain-like" CG32115 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0063644 CE3-2 "Calcineurin enhancer, chromosome 3, group 2" http://flybase.org/reports/FBgn0063644 gene - - - CE3-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002374 l(3)91Ff lethal (3) 91Ff http://flybase.org/reports/FBgn0002374 - gene - - - "l(3)BE91, l(3)BE90, l(3)91Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0027085 LeuRS-m "Leucyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0027085 FBgn0035576 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002300, InterPro:IPR002302, InterPro:IPR009080, InterPro:IPR015413 aminoacyl-tRNA editing activity ; GO:0002161 | inferred from electronic annotation with InterPro:IPR009008 leucine-tRNA ligase activity ; GO:0004823 | traceable author statement leucine-tRNA ligase activity ; GO:0004823 | inferred from sequence or structural similarity with UniProtKB:Q15031" leucyl-tRNA aminoacylation ; GO:0006429 | traceable author statement leucyl-tRNA aminoacylation ; GO:0006429 | inferred from sequence or structural similarity with UniProtKB:Q15031 mitochondrial translation ; GO:0032543 | inferred from biological aspect of ancestor with PANTHER:PTN000236416 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q15031 mitochondrion ; GO:0005739 | traceable author statement "LeuRS, LRS, CG7479, Aats-leu, LeuRS-m" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002302:Leucine-tRNA ligase, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR015413:Methionyl/Leucyl tRNA synthetase, IPR009008:Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR002300:Aminoacyl-tRNA synthetase, class Ia, IPR013155:Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding" CG7479 11-Aug-17 DroID_v2017_08 Drer\lars2 Scer\NAM2 Cele\lars-2 Xtro\lars2 Mmus\Lars2 Hsap\LARS2 embryonic stage

ubiquitous "viable,visible,decreased cell size,cell autonomous,somatic clone" "trichogen cell,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0266198 CR44893 - http://flybase.org/reports/FBgn0266198 non_protein_coding_gene - - - "CR44893, lincRNA.1004" - CR44893 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001327 ks-1 male fertility factor ks1 http://flybase.org/reports/FBgn0001327 - gene - - - "Sms1, ks-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0023470 anon-30Fd anon-30Fd http://flybase.org/reports/FBgn0023470 - gene - - - anon-30Fd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085520 CR40801 - http://flybase.org/reports/FBgn0085520 pseudogene_attribute - - - "CG40801, CR40801" - CR40801 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010926 l(3)07882 lethal (3) 07882 http://flybase.org/reports/FBgn0010926 FBgn0038517 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from sequence or structural similarity with UniProtKB:Q99207 ribosomal small subunit biogenesis ; GO:0042274 | inferred from sequence or structural similarity with UniProtKB:Q99207 rRNA processing ; GO:0006364 | inferred from sequence or structural similarity with UniProtKB:Q99207 maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000573053 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000573053 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000573053 Noc4p-Nop14p complex ; GO:0030692 | inferred from biological aspect of ancestor with PANTHER:PTN000573053 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q99207 "CG5824, l(3)07882" IPR007276:Nucleolar protein 14 CG5824 11-Aug-17 DroID_v2017_08 Drer\nop14 Scer\NOP14 Cele\Y48G1A.4 Xtro\nop14 Mmus\Nop14 Hsap\NOP14 "partially lethal - majority die,recessive,lethal" FBgn0050291 CG30291 - http://flybase.org/reports/FBgn0050291 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | inferred from sequence or structural similarity with UniProtKB:Q9JLH7 endomembrane system ; GO:0012505 | inferred from direct assay "CG3282, CG30291" IPR008491:Protein of unknown function DUF773 CG30291 11-Aug-17 DroID_v2017_08 Drer\cdk5rap3 - Cele\cdkr-3 Xtro\cdk5rap3 Mmus\Cdk5rap3 Hsap\CDK5RAP3 viable FBgn0002010 l(2)36Fc lethal (2) 36Fc http://flybase.org/reports/FBgn0002010 - gene - - - "36Fc, Fc, l(2)E53, l(2)36Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0041158 dos::tor dos::tor http://flybase.org/reports/FBgn0041158 engineered_fusion_gene - - - dos::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012300 Dfd::Ubx Dfd::Ubx http://flybase.org/reports/FBgn0012300 - engineered_fusion_gene - - - Dfd::Ubx - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" head FBgn0023432 l(2)55Ca lethal (2) 55Ca http://flybase.org/reports/FBgn0023432 - gene - - - l(2)55Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046689 Takl1 Tak1-like 1 http://flybase.org/reports/FBgn0046689 protein_coding_gene "MAP kinase kinase kinase activity ; GO:0004709 | inferred from electronic annotation with InterPro:IPR017421 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR017421 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with HGNC:6859 protein kinase activity ; GO:0004672 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058" protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with Tak1 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 "TAKL1, anon-AE003732.1, CG31421, Takl1, FBgn0046689, takl1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017421:Mitogen-activated protein (MAP) kinase kinase kinase 7, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG31421 11-Aug-17 DroID_v2017_08 "Drer\map3k9, Drer\pbk, Drer\map3k10, Drer\zgc:66101, Drer\lrrk2, Drer\ripk4, Drer\ripk3, Drer\chek2, Drer\map4k6, Drer\ripk2, Drer\LOC405768, Drer\sik1, Drer\mast1b, Drer\stk36, Drer\mark1, Drer\zak, Drer\plk3, Drer\map3k7, Drer\mark3b, Drer\dstyk, Drer\mos, Drer\ripk1l, Drer\si:ch211-120p12.3" "Scer\SKS1, Scer\SNF1" "Cele\spe-8, Cele\sad-1, Cele\mom-4, Cele\Y105C5A.24" "Xtro\lrrk2, Xtro\ankk1, Xtro\pbk, Xtro\sik2, Xtro\zak, Xtro\dstyk, Xtro\ripk1, Xtro\mlkl, Xtro\map3k7, Xtro\mapk15, Xtro\brsk1, Xtro\LOC100490493, Xtro\map3k10, Xtro\lrrk1, Xtro\ripk4, Xtro\map3k9, Xtro\hunk" "Mmus\Zak, Mmus\Mark2, Mmus\Smok2b, Mmus\Gm7358, Mmus\Gm4922, Mmus\Smok3b, Mmus\Mark3, Mmus\Prkch, Mmus\Gm14147, Mmus\Pbk, Mmus\Mlkl, Mmus\BC021891, Mmus\Ripk2, Mmus\Dstyk, Mmus\Mos, Mmus\Ripk3, Mmus\Sik3, Mmus\Sik2, Mmus\Smok2a, Mmus\Snrk, Mmus\Lrrk1, Mmus\Ripk4, Mmus\Ripk1, Mmus\4921509C19Rik, Mmus\Map3k9, Mmus\Map3k11, Mmus\Map3k7, Mmus\Map3k10, Mmus\Lrrk2" "Hsap\RIPK2, Hsap\DSTYK, Hsap\MAP3K9, Hsap\LRRK2, Hsap\RIPK1, Hsap\MLKL, Hsap\SNRK, Hsap\BRSK1, Hsap\MAP3K7, Hsap\LRRK1, Hsap\PBK, Hsap\MARK2, Hsap\MAP3K10, Hsap\MARK3, Hsap\RIPK4, Hsap\MOS, Hsap\MAP3K20, Hsap\MAP3K21, Hsap\MAP3K11, Hsap\SIK2, Hsap\RIPK3" viable FBgn0003421 sld slender http://flybase.org/reports/FBgn0003421 - gene - - - sld - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female,poor,male,reduced,visible,male fertile,male sterile" "adult abdomen,eye,wing" FBgn0020317 anon-8F6 anon-8F6 http://flybase.org/reports/FBgn0020317 - gene - - - "8F6, anon-8F6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041336 Cyp6t2Psi Cyp6t2Psi http://flybase.org/reports/FBgn0041336 pseudogene_attribute - - - "6t2p, Cyp6t2p, CR31621, Cyp6t2Psi" - CR31621 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065576 l(2)SH0953 lethal (2) SH0953 http://flybase.org/reports/FBgn0065576 gene - - - "l(2)SH0953, l(2)SH2 0953" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263496 CR43485 - http://flybase.org/reports/FBgn0263496 non_protein_coding_gene - - - CR43485 - CR43485 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036319 Ent3 Equilibrative nucleoside transporter 3 http://flybase.org/reports/FBgn0036319 protein_coding_gene monoamine transmembrane transporter activity ; GO:0008504 | inferred from electronic annotation with InterPro:IPR030198 nucleoside transmembrane transporter activity ; GO:0005337 | inferred from sequence or structural similarity with HGNC:11003 inferred from sequence or structural similarity with HGNC:11004 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR030198 nucleoside transport ; GO:0015858 | inferred from sequence or structural similarity with HGNC:11003 inferred from sequence or structural similarity with HGNC:11004 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002259, InterPro:IPR030198 integral component of membrane ; GO:0016021 | inferred from sequence model" "DmENT3, CG11010, Ent3, ent3, DmEnt3" "IPR020846:Major facilitator superfamily domain, IPR030198:Equilibrative nucleoside transporter 4, IPR002259:Equilibrative nucleoside transporter" CG11010 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-160d14.6, Drer\slc29a3, Drer\slc29a1a, Drer\slc29a4, Drer\slc29a1b, Drer\slc29a2, Drer\LOC100334018" Scer\FUN26 - Xtro\slc29a2 "Mmus\Slc29a4, Mmus\Slc29a1, Mmus\Slc29a2, Mmus\Slc29a3" "Hsap\SLC29A4, Hsap\SLC29A2, Hsap\SLC29A1, Hsap\SLC29A3" viable FBgn0263124 Ubx::Csal\Ubx2 - http://flybase.org/reports/FBgn0263124 engineered_fusion_gene - - - "Ubx::Zzzz\Ubx2, Ubx::Csal\Ubx2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084045 CG41485 - http://flybase.org/reports/FBgn0084045 protein_coding_gene - - - CG41485 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005167 l(2)G562 lethal (2) G562 http://flybase.org/reports/FBgn0005167 - gene - - - l(2)G562 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260933 rempA reduced mechanoreceptor potential A http://flybase.org/reports/FBgn0260933 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of sound ; GO:0007605 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from expression pattern non-motile cilium assembly ; GO:1905515 | inferred from sequence or structural similarity with Oseg1 intraciliary retrograde transport ; GO:0035721 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype non-motile cilium ; GO:0097730 | inferred from direct assay axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000404360 intraciliary transport particle A ; GO:0030991 | inferred from biological aspect of ancestor with PANTHER:PTN000404361 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN000404360 "Oseg3, RempA, IFT140, rempA, IFT40, CG11838, oseg3, remp, OSEG3, CHE-11, OSEG, Che-11, REMPA" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR011990:Tetratricopeptide-like helical domain" CG11838 11-Aug-17 DroID_v2017_08 Drer\ift140 - Cele\che-11 Xtro\ift140 Mmus\Ift140 Hsap\IFT140 FBgn0003587 Su(var)2-4 Suppressor of variegation 2-4 http://flybase.org/reports/FBgn0003587 - gene - - - "Su-var(2)4, Su(var)b[5401], Su(var)b5401, Su(var)2-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0002667 mat(2)ea-D maternal effect early arrest D http://flybase.org/reports/FBgn0002667 - gene - - - "mat(2)earlyQD68, mat(2)ea-D" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0022248 l(2)k01302 lethal (2) k01302 http://flybase.net/reports/FBgn0022248.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0034397 CG15082 - http://flybase.org/reports/FBgn0034397 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15082 - CG15082 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038376 Hmt-1 Heavy metal tolerance factor 1 http://flybase.org/reports/FBgn0038376 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:Q9NP58 heme transporter activity ; GO:0015232 | inferred from sequence or structural similarity with UniProtKB:Q9NP58 cadmium ion transmembrane transporter activity ; GO:0015086 | NOT inferred from genetic interaction with PomBase:SPCC737.09c" cadmium ion transmembrane transport ; GO:0070574 | NOT inferred from genetic interaction with PomBase:SPCC737.09c heme transport ; GO:0015886 | inferred from sequence or structural similarity with UniProtKB:Q9NP58 response to cadmium ion ; GO:0046686 | inferred from genetic interaction with PomBase:SPCC737.09c integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011527 vacuolar membrane ; GO:0005774 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q9NP58 "EP(3)3387, Hmt-1, hmt-1, CG4225" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR032410:Mitochondrial ABC-transporter, N-terminal five TM domain" CG4225 11-Aug-17 DroID_v2017_08 "Drer\abcb6a, Drer\abcb7, Drer\abcb6b" Scer\ATM1 "Cele\hmt-1, Cele\abtm-1" "Xtro\abcb7, Xtro\abcb6" "Mmus\Abcb6, Mmus\Abcb7" "Hsap\ABCB7, Hsap\ABCB6" "viable,fertile" FBgn0016697 Prosalpha5 Proteasome alpha5 subunit http://flybase.org/reports/FBgn0016697 - protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426 proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay" "154644_at, prosMA5, PSMA5, PRCZ, alpha5_dm, CG10938, ProsMA5, Prosalpha5, PSA5_DROME, Alpha-5, alpha5, alpha-5" "IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR023332:Proteasome alpha-type subunit, IPR033812:Proteasome subunit alpha5, IPR029055:Nucleophile aminohydrolases, N-terminal" CG10938 11-Aug-17 DroID_v2017_08 "Drer\psma8, Drer\psma2, Drer\psma5" Scer\PUP2 Cele\pas-5 "Xtro\psma5, Xtro\psma2, Xtro\psma7" "Mmus\Psma5, Mmus\Psma2, Mmus\Psma7, Mmus\Psma8" "Hsap\PSMA8, Hsap\PSMA5, Hsap\PSMA2, Hsap\PSMA7" lethal DRSC07514 IEK -2.13486607 -3.202508628 -0.045359637 -1.782343105 1.965226568 1.665925402 FBgn0010056 JmE Ju myoE http://flybase.org/reports/FBgn0010056 - gene - - - "Jm E, JmE" - - 11-Aug-17 DroID_v2017_08 - - - - - - aging defective FBgn0042097 yeti-MBT yeti Malignant Brain Tumor http://flybase.org/reports/FBgn0042097 gene - mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs - "SWC5, yeti-MBT, yeti" - - 11-Aug-17 DroID_v2017_08 - - - - - - polytene chromosome FBgn0004823 fs(2)ltoAPV63 female sterile (2) ltoAPV63 http://flybase.org/reports/FBgn0004823 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoAPV63 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0010052 Jhe Juvenile hormone esterase http://flybase.org/reports/FBgn0010052 FBgn0034077 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with CG3776 carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay juvenile-hormone esterase activity ; GO:0004453 | inferred from direct assay juvenile hormone catabolic process ; GO:0006719 | inferred from direct assay male mating behavior ; GO:0060179 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "JHE, CG8425, JH, Jhe, jhe, DmJhe" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG8425 11-Aug-17 DroID_v2017_08 "Drer\nlgn4a, Drer\nlgn4b, Drer\nlgn3b, Drer\si:ch211-93f2.1, Drer\nlgn2a, Drer\nlgn1, Drer\ces3, Drer\nlgn2b, Drer\cel.1, Drer\nlgn3a, Drer\ces2, Drer\cell" - "Cele\T28C12.5, Cele\F13H6.3, Cele\C52A10.1, Cele\C52A10.2, Cele\K11G9.2, Cele\Y71H2AM.13, Cele\F15A8.6, Cele\F07C4.12, Cele\K07C11.4, Cele\K11G9.3, Cele\K11G9.1, Cele\F56C11.6, Cele\T28C12.4, Cele\T07H6.1, Cele\B0238.1, Cele\ges-1, Cele\glit-1, Cele\R173.3" "Xtro\cel, Xtro\nlgn2, Xtro\nlgn3, Xtro\ces3, Xtro\ces2, Xtro\LOC100494782, Xtro\nlgn4x" "Mmus\Ces1h, Mmus\Ces5a, Mmus\Ces2g, Mmus\Ces1g, Mmus\Ces2h, Mmus\Nlgn1, Mmus\Ces1e, Mmus\Ces2f, Mmus\Nlgn3, Mmus\Cel, Mmus\Nlgn2, Mmus\Ces2a, Mmus\Ces3a, Mmus\Ces1d, Mmus\Ces1c, Mmus\Ces4a, Mmus\Tg, Mmus\Ces2e, Mmus\Ces2c, Mmus\Ces1b, Mmus\Ces1f, Mmus\Ces2b, Mmus\Ces3b" "Hsap\NLGN2, Hsap\CES3, Hsap\NLGN4Y, Hsap\CES2, Hsap\NLGN3, Hsap\CES5A, Hsap\CEL, Hsap\TG, Hsap\NLGN1, Hsap\NLGN4X, Hsap\CES1, Hsap\CES4A" "viable,mating defective,male,recessive,hyperactive,conditional,chemical resistant" FBgn0034644 CG10082 - http://flybase.org/reports/FBgn0034644 protein_coding_gene "inositol-1,4,5-trisphosphate 3-kinase activity ; GO:0008440 | inferred from electronic annotation with InterPro:IPR005522" - - "anon-WO0172774.149, CG10082, dmIP6K" "IPR005522:Inositol polyphosphate kinase, IPR015943:WD40/YVTN repeat-like-containing domain" CG10082 11-Aug-17 DroID_v2017_08 "Drer\ip6k2b, Drer\ip6k1, Drer\ipmkb, Drer\ip6k2a" "Scer\ARG82, Scer\KCS1" "Cele\ZK795.1, Cele\F30A10.3, Cele\Y22D7AR.6, Cele\T20F7.3" "Xtro\ip6k2, Xtro\ip6k1" "Mmus\Ip6k2, Mmus\Ip6k3, Mmus\Ip6k1, Mmus\Ipmk" "Hsap\IPMK, Hsap\IP6K2, Hsap\IP6K3, Hsap\IP6K1" "viable,partially lethal - majority die,recessive" DRSC04054 K 0.560440401 -0.962290212 -0.141540065 0.845679138 0.099701232 1.524920336 FBgn0031134 CG1314 - http://flybase.org/reports/FBgn0031134 protein_coding_gene - - - "anon-WO0140519.251, CG1314" IPR031732:Protein of unknown function DUF4729 CG1314 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259962 Sfp33A1 Seminal fluid protein 33A1 http://flybase.org/reports/FBgn0259962 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp33A1, CG42472" - CG42472 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025768 l(3)89Ch lethal (3) 89Ch http://flybase.org/reports/FBgn0025768 - gene - - - "l(3)M2912, l(3)89Ch" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034626 CG10795 - http://flybase.org/reports/FBgn0034626 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "LD27358, CG10795" IPR007829:TM2 domain CG10795 11-Aug-17 DroID_v2017_08 "Drer\LOC100535396, Drer\LOC797974, Drer\tm2d1, Drer\si:dkey-229d11.5, Drer\slc2a6, Drer\si:ch1073-263o8.2, Drer\slc2a8" - "Cele\M01G12.9, Cele\Y66D12A.21, Cele\ZK858.5, Cele\M01G12.14, Cele\C41D11.9" "Xtro\slc2a6, Xtro\tm2d1, Xtro\slc2a8" "Mmus\Slc2a8, Mmus\Acrv1, Mmus\Pate1, Mmus\Pate4, Mmus\Gm7257, Mmus\1700013H16Rik, Mmus\Gm5615, Mmus\Slc2a6, Mmus\Tm2d1, Mmus\Gm17689, Mmus\Pate3" "Hsap\ACRV1, Hsap\PATE1, Hsap\SLC2A6, Hsap\PATE4, Hsap\TM2D1, Hsap\PATE3, Hsap\SLC2A8" viable FBgn0262945 CR43264 - http://flybase.org/reports/FBgn0262945 non_protein_coding_gene - - - CR43264 - CR43264 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262467 Scox Synthesis of cytochrome c oxidase http://flybase.org/reports/FBgn0262467 protein_coding_gene copper chaperone activity ; GO:0016531 | inferred from sequence or structural similarity with UniProt:O75880 inferred from sequence or structural similarity with UniProtKB:O43819 cytochrome-c oxidase activity ; GO:0004129 | inferred from mutant phenotype copper ion transport ; GO:0006825 | inferred from electronic annotation with InterPro:IPR017276 cellular copper ion homeostasis ; GO:0006878 | inferred from electronic annotation with InterPro:IPR017276 cytochrome complex assembly ; GO:0017004 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype oocyte construction ; GO:0007308 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with UniProt:O75880 inferred from sequence or structural similarity with UniProtKB:O43819 positive regulation of ATP biosynthetic process ; GO:2001171 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype mitochondrial inner membrane ; GO:0005743 | inferred from electronic annotation with InterPro:IPR017276 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProt:O75880 inferred from sequence or structural similarity with UniProtKB:O43819 "CG8885, Scox, SCO, scox, SCOX, dSco1, l(2)SH1783, l(2)SH2 1783, SCO1" "IPR003782:Copper chaperone SCO1/SenC, IPR012336:Thioredoxin-like fold, IPR017276:Synthesis of cytochrome c oxidase, Sco1/Sco2" CG8885 11-Aug-17 DroID_v2017_08 "Drer\sco2, Drer\sco1" "Scer\SCO2, Scer\SCO1" "Cele\C06C3.8, Cele\T10B5.7, Cele\C41H7.4, Cele\C14E2.6, Cele\sco-1, Cele\C08A9.6, Cele\Y51H4A.5, Cele\C41H7.6, Cele\C40H1.2, Cele\B0454.9" "Xtro\sco2, Xtro\pnliprp2, Xtro\sco1, Xtro\pnliprp3" "Mmus\Pnlip, Mmus\Pnliprp1, Mmus\Pnliprp2, Mmus\Sco2, Mmus\Sco1" "Hsap\PNLIPRP3, Hsap\SCO1, Hsap\PNLIP, Hsap\SCO2" DRSC03117 E -0.431363088 -0.263998782 -1.668874892 0.021571532 0.408687422 -0.590105257 FBgn0086446 DCTN6-p27 "Dynactin 6, p27 subunit" http://flybase.org/reports/FBgn0086446 protein_coding_gene - microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynactin complex ; GO:0005869 | inferred from electronic annotation with InterPro:IPR027777 dynactin complex ; GO:0005869 | inferred from sequence or structural similarity "l(2)37Ce, CG17347, Ce, l(2)E62, l(2)37Ce)E62, DCTN6, DCTN6-p27, P27" "IPR011004:Trimeric LpxA-like, IPR001451:Hexapeptide repeat, IPR027777:Dynactin subunit 6" CG17347 11-Aug-17 DroID_v2017_08 Drer\zgc:112102 - Cele\dnc-6 Xtro\dctn6 Mmus\Dctn6 Hsap\DCTN6 FBgn0004559 Su(var)308 Suppressor of variegation 308 http://flybase.org/reports/FBgn0004559 - gene - - - Su(var)308 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032730 CG10431 - http://flybase.org/reports/FBgn0032730 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612, InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000003381" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR027775 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 "dmCG10431, CG10431" "IPR006612:Zinc finger, C2CH-type, IPR012934:Zinc finger, AD-type, IPR027775:C2H2- zinc finger protein family subset, IPR013087:Zinc finger C2H2-type" CG10431 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-40k21.9, Drer\thap1, Drer\si:dkey-228b2.6, Drer\zgc:113364, Drer\thap7, Drer\thap3, Drer\zgc:163143, Drer\arl14ep, Drer\LOC101882293, Drer\si:ch73-389k6.1" Scer\RPN4 - "Xtro\thap7, Xtro\thap5, Xtro\sall1, Xtro\thap1" "Mmus\Zkscan6, Mmus\Zfp446, Mmus\Zfp641, Mmus\Zfp174, Mmus\Thap3, Mmus\Zscan29, Mmus\Thap2, Mmus\Zfp444, Mmus\Thap1, Mmus\Zfp202, Mmus\Thap7, Mmus\Zscan18, Mmus\Zscan5b, Mmus\Zkscan17, Mmus\Zkscan2, Mmus\Zfp369, Mmus\Zfp110" "Hsap\ZNF641, Hsap\ZKSCAN2, Hsap\THAP8, Hsap\ZSCAN32, Hsap\ZNF496, Hsap\ZNF174, Hsap\THAP7, Hsap\ZNF202, Hsap\ZNF446, Hsap\PEG3, Hsap\ZNF18, Hsap\THAP5, Hsap\THAP3, Hsap\ZSCAN1, Hsap\ZSCAN29, Hsap\THAP2, Hsap\ZSCAN5A, Hsap\ZSCAN18, Hsap\ZNF444, Hsap\THAP1, Hsap\THAP6, Hsap\ZSCAN5B" "viable,neuroanatomy defective" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC" FBgn0085501 CG40609 - http://flybase.org/reports/FBgn0085501 protein_coding_gene - - - CG40609 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040711 CG15409 - http://flybase.org/reports/FBgn0040711 protein_coding_gene - - - CG15409 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005180 l(2)S3 lethal of Seto 3 http://flybase.org/reports/FBgn0005180 - gene - - - l(2)S3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" "puparium,prepupa,pupal tracheal system" FBgn0052421 tRNA:Val-TAC-1-2 transfer RNA:Valine-TAC 1-2 http://flybase.org/reports/FBgn0052421 tRNA_gene GUA codon-amino acid adaptor activity ; GO:0033451 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033451 cytosol ; GO:0005829 | inferred by curator from GO:0033451 "AE002602.trna12-ValTAC, valine tRNA, tRNA[Val][[3a]], tRNA:val3a:64D, tRNA:V3a:64D, tRNA:V3a, tRNA:V:TAC:AE002602-a, CR32421, chr3L.trna46-ValTAC, tRNA-Val[UAC], tRNA:Val-TAC-1-2, tRNA:CR32421, tRNA-Val-TAC-1-2, GUA" - CR32421 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061111 l(3)S006615 lethal (3) S006615 http://flybase.org/reports/FBgn0061111 gene - - - "0066/15, l(3)S006615" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0052603 CG32603 - http://flybase.org/reports/FBgn0052603 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32603 IPR022727:Pupal cuticle protein C1 CG32603 11-Aug-17 DroID_v2017_08 "Drer\mdc1, Drer\pou2af1, Drer\zgc:174862" - Cele\abu-10 - "Mmus\Pou2af1, Mmus\Peg3, Mmus\Mdc1" "Hsap\POU2AF1, Hsap\PEG3" DRSC21586 E 0.49237136 0.341005411 0.575960863 1.838739213 1.426685488 -0.521452156 FBgn0021822 l(2)k16207 lethal (2) k16207 http://flybase.org/reports/FBgn0021822 - gene - - - l(2)k16207 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065767 l(2)SH0471 lethal (2) SH0471 http://flybase.org/reports/FBgn0065767 gene - - - "l(2)SH0471, l(2)SH2 0471" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024878 l(2)52Fc lethal (2) 52Fc http://flybase.org/reports/FBgn0024878 - gene - - - "D8.13, l(2)52Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065232 l(2)SH2169 lethal (2) SH2169 http://flybase.org/reports/FBgn0065232 gene - - - "l(2)SH2169, l(2)SH2 2169" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033097 Zip42C.2 Zinc/iron regulated transporter-related protein 42C.2 http://flybase.org/reports/FBgn0033097 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred from direct assay zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016323 zinc II ion transmembrane import ; GO:0071578 | inferred from genetic interaction with Zip42C.1 detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "dZip42C.2, dZip2, CG9430, Zip42C.2, cg9430, dZIP42C.2" IPR003689:Zinc/iron permease CG9430 11-Aug-17 DroID_v2017_08 "Drer\slc39a1, Drer\slc39a3" "Scer\ZRT2, Scer\ZRT1, Scer\WSS1" "Cele\F31C3.4, Cele\C06G8.3, Cele\F30B5.7, Cele\Y54G9A.4, Cele\C18A3.2, Cele\F55F8.9" "Xtro\slc39a3, Xtro\slc39a2, Xtro\slc39a1" "Mmus\Slc39a2, Mmus\Slc39a1, Mmus\Slc39a3" "Hsap\SLC39A3, Hsap\SLC39A2, Hsap\SLC39A1" "partially lethal - majority die,some die during pupal stage,lethal - all die during pupal stage,viable,lethal - all die during larval stage" FBgn0014324 l(3)ry3 lethal (3) ry3 http://flybase.org/reports/FBgn0014324 - gene - - - l(3)ry3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015995 l(2)k08807 lethal (2) k08807 http://flybase.org/reports/FBgn0015995 - gene - - - l(2)k08807 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" presumptive embryonic/larval peripheral nervous system FBgn0038173 Adgf-C Adenosine deaminase-related growth factor C http://flybase.org/reports/FBgn0038173 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine deaminase activity ; GO:0004000 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine catabolic process ; GO:0006154 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR006331, InterPro:IPR013659 extracellular space ; GO:0005615 | inferred from sequence model" "ADGF-C, CG9345, adgfc, Adgf-C, AdgfC" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG9345 11-Aug-17 DroID_v2017_08 "Drer\cecr1a, Drer\ada, Drer\adal, Drer\cecr1b" Scer\AAH1 Cele\C44B7.12 "Xtro\ada.2, Xtro\ada, Xtro\adal, Xtro\cecr1" "Mmus\Ada, Mmus\Adal" "Hsap\ADA, Hsap\ADAL, Hsap\CECR1" viable FBgn0003114 plu plutonium http://flybase.org/reports/FBgn0003114 FBgn0034492 protein_coding_gene - negative regulation of DNA replication ; GO:0008156 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | traceable author statement egg activation ; GO:0007343 | inferred from mutant phenotype single fertilization ; GO:0007338 | inferred from mutant phenotype serine/threonine protein kinase complex ; GO:1902554 | inferred from physical interaction with png "Plu, PLU, CG9183, plu" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG9183 11-Aug-17 DroID_v2017_08 - - Cele\C01F1.6 - - Hsap\POTEA embryonic stage | 0-6 hr "lethal,maternal effect,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,female sterile,meiotic cell cycle defective" "nucleus | embryonic stage,oocyte nucleus,nuclear chromosome,male pronucleus,female pronucleus,polar body nucleus,pronucleus" FBgn0040717 Nplp4 Neuropeptide-like precursor 4 http://flybase.org/reports/FBgn0040717 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | non-traceable author statement neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement extracellular region ; GO:0005576 | non-traceable author statement "NPLP4, CG15361, Nplp4, YSY" - CG15361 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC00391 K 0.125492502 0.573520674 0.99485833 0.041946835 0.886170861 1.982170871 FBgn0266443 CG45073 - http://flybase.org/reports/FBgn0266443 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45073, CG18682" IPR006631:Protein of unknown function DM4/12 CG45073 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039108 CG10232 - http://flybase.org/reports/FBgn0039108 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP14, CG10232" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG10232 11-Aug-17 DroID_v2017_08 Drer\masp2 - "Cele\try-3, Cele\try-1" - Mmus\Klk1b5 - viable FBgn0035087 CG2765 - http://flybase.org/reports/FBgn0035087 protein_coding_gene myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A - - CG2765 IPR009786:Spot 14 family CG2765 11-Aug-17 DroID_v2017_08 "Drer\thrsp, Drer\mid1ip1l, Drer\mid1ip1b, Drer\mid1ip1a" - - "Xtro\mid1ip1, Xtro\thrsp" "Mmus\Mid1ip1, Mmus\Thrsp" "Hsap\MID1IP1, Hsap\THRSP" viable FBgn0053558 mim missing-in-metastasis http://flybase.org/reports/FBgn0053558 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR030127 phospholipid binding ; GO:0005543 | inferred from direct assay SH3 domain binding ; GO:0017124 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with mim plasma membrane organization ; GO:0007009 | inferred from electronic annotation with InterPro:IPR013606 filopodium assembly ; GO:0046847 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype negative regulation of receptor-mediated endocytosis ; GO:0048261 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from physical interaction with Cortactin "CG9469, anon-EST:fe1E4, CG33352, mim, CG33558, dmim, MIM, Dm_2R:10851, Mim" "IPR013606:IMD/I-BAR domain, IPR030127:I-BAR domain containing protein MIM/ABBA, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011990:Tetratricopeptide-like helical domain, IPR011989:Armadillo-like helical" CG33558 11-Aug-17 DroID_v2017_08 "Drer\mtss1l, Drer\mtss1, Drer\mtss1la" - Cele\M04F3.5 "Xtro\mtss1.1, Xtro\mtss1l, Xtro\mtss1.2" "Mmus\Mtss1, Mmus\Mtss1l" "Hsap\MTSS1L, Hsap\MTSS1" "female sterile,partially,locomotor behavior defective,viable" "border follicle cell,germline cell" FBgn0058263 MFS17 Major Facilitator Superfamily Transporter 17 http://flybase.org/reports/FBgn0058263 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "bs24e02.y1, BEST:LD07241, CG40263, MFS17" "IPR011701:Major facilitator superfamily, IPR027378:Cyclic nucleotide-regulated ion channel, N-terminal domain, IPR020846:Major facilitator superfamily domain" CG40263 11-Aug-17 DroID_v2017_08 "Drer\slc17a5, Drer\si:ch1073-513e17.1" "Scer\THI73, Scer\TNA1, Scer\DAL5, Scer\YIL166C" "Cele\F56A4.12, Cele\C01B4.8, Cele\C35A5.3, Cele\F10C2.7, Cele\T22F3.11, Cele\slc-17.3, Cele\M162.5, Cele\slc-17.1, Cele\T28H11.8, Cele\H11E01.2, Cele\T19D12.9, Cele\F59A1.13, Cele\Y19D10A.11, Cele\slc-17.5, Cele\C18H9.5, Cele\slc-17.2, Cele\C01B4.7, Cele\slc-17.8, Cele\C39E9.7, Cele\Y19D10A.5, Cele\T22F3.10, Cele\F44E7.7, Cele\T22F3.8, Cele\M117.1, Cele\Y19D10A.8, Cele\Y15E3A.4, Cele\slc-17.6, Cele\T02B11.6, Cele\T27D12.1, Cele\F11A5.9, Cele\R10D12.1, Cele\K08C7.1, Cele\T19D12.10, Cele\slc-17.4, Cele\Y19D10A.4, Cele\D1046.4, Cele\slc-17.9, Cele\Y4C6B.4, Cele\F56A4.10, Cele\cima-1, Cele\Y4C6B.3, Cele\T01H3.3, Cele\W04C9.6, Cele\slc-17.7, Cele\K11G9.5, Cele\C18D1.2, Cele\T22F3.7, Cele\Y51B9A.6, Cele\F41C3.2" - "Mmus\Slc17a1, Mmus\Slc17a2, Mmus\Slc17a4, Mmus\Slc17a5, Mmus\Slc17a3" "Hsap\SLC17A4, Hsap\SLC17A2, Hsap\SLC17A1, Hsap\SLC17A5, Hsap\SLC17A3" FBgn0010643 l(2)07837 lethal (2) 07837 http://flybase.net/reports/FBgn0010643.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0035047 Pof Painting of fourth http://flybase.org/reports/FBgn0035047 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA binding ; GO:0003723 | non-traceable author statement chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with egg - autosome ; GO:0030849 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay "Pof, cg3691, CG3691, POF, pof" IPR000504:RNA recognition motif domain CG3691 11-Aug-17 DroID_v2017_08 - - - - - - "viable,wild-type" FBgn0065581 l(2)SH0941 lethal (2) SH0941 http://flybase.org/reports/FBgn0065581 gene - - - "l(2)SH0941, l(2)SH2 0941" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033721 CG13159 - http://flybase.org/reports/FBgn0033721 protein_coding_gene - - - "BcDNA:RE25177, CG13159" - CG13159 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum DRSC06283 EK -0.60517028 -0.955956894 1.636995156 0.130856873 2.159841255 0.55996082 FBgn0051131 CG31131 - http://flybase.org/reports/FBgn0051131 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31131 - CG31131 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043559 Su(ro[DOM])1480 Su(ro[DOM])1480 http://flybase.org/reports/FBgn0043559 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])1480 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0063598 CS3-1 "Calcineurin suppressor, chromosome 3, group 1" http://flybase.org/reports/FBgn0063598 gene - - - CS3-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050203 CG30203 - http://flybase.org/reports/FBgn0050203 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CT39323, CG17740, CG30203" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR002861:Reeler domain, IPR009465:Spondin, N-terminal" CG30203 11-Aug-17 DroID_v2017_08 "Drer\spon1b, Drer\thsd7aa, Drer\spon1a, Drer\thsd7bb, Drer\thsd7ba" - Cele\spon-1 "Xtro\thsd7b, Xtro\spon1, Xtro\thsd7a" "Mmus\Spon1, Mmus\Thsd7b, Mmus\Thsd7a" "Hsap\SPON1, Hsap\THSD7A, Hsap\THSD7B" viable DRSC06690 K -0.252730836 -0.12889358 0.101228917 0.287352377 2.769842121 1.284844502 FBgn0260049 flr flare http://flybase.org/reports/FBgn0260049 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity with NCBI_gi:1168395 actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000458108 "regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype actin filament depolymerization ; GO:0030042 | inferred from mutant phenotype regulation of actin filament depolymerization ; GO:0030834 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of actin filament depolymerization ; GO:0030836 | inferred from biological aspect of ancestor with PANTHER:PTN000458108 sarcomere organization ; GO:0045214 | inferred from mutant phenotype negative regulation of Arp2/3 complex-mediated actin nucleation ; GO:0034316 | inferred from genetic interaction with GMF, Arpc5 imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype" "actomyosin, actin portion ; GO:0042643 | inferred from biological aspect of ancestor with PANTHER:PTN000458108 cytoskeleton ; GO:0005856 | inferred from direct assay cortical actin cytoskeleton ; GO:0030864 | inferred from biological aspect of ancestor with PANTHER:PTN000458108" "CG10724, flr, AIP1, Aip1, aip1" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG10724 11-Aug-17 DroID_v2017_08 "Drer\LOC108179016, Drer\wdr1" Scer\AIP1 "Cele\aipl-1, Cele\unc-78, Cele\wdr-48" Xtro\wdr1 Mmus\Wdr1 Hsap\WDR1 FBgn0035725 Mis12 Mis12 http://flybase.org/reports/FBgn0035725 protein_coding_gene - chromosome segregation ; GO:0007059 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic chromosome movement towards spindle pole ; GO:0007079 | inferred from mutant phenotype "kinetochore ; GO:0000776 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay Ndc80 complex ; GO:0031262 | inferred from direct assay" "BcDNA:RE19545, CG18156, dmMis12, Mis12, Mis-12" - CG18156 11-Aug-17 DroID_v2017_08 Drer\mis12 - - Xtro\mis12 - Hsap\MIS12 "mitotic cell cycle defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "condensed nuclear chromosome,metaphase,nucleus,spindle,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0085799 CR41544 - http://flybase.org/reports/FBgn0085799 rRNA_gene - - - CR41544 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032910 CG9265 - http://flybase.org/reports/FBgn0032910 protein_coding_gene - - - CG9265 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG9265 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-221h15.4, Drer\rdh20, Drer\sdr16c5a, Drer\sdr16c5b, Drer\rdh10b, Drer\dhrs3a, Drer\rdh10a, Drer\dhrs3b" "Scer\YDL114W, Scer\TDA5" "Cele\dhs-29, Cele\dhs-3, Cele\dhs-19, Cele\dhs-4" "Xtro\hsd17b11, Xtro\hsd17b13, Xtro\rdh10, Xtro\sdr16c5, Xtro\dhrs3" "Mmus\Sdr16c6, Mmus\Hsd17b13, Mmus\Sdr16c5, Mmus\Hsd17b11, Mmus\Dhrs3, Mmus\Rdh10" "Hsap\HSD17B13, Hsap\RDH10, Hsap\HSD17B11, Hsap\SDR16C5, Hsap\DHRS3" "viable,fertile" DRSC03178 E -0.925043617 -0.454212092 -1.792542037 0.463251428 -0.050592619 -0.829007981 FBgn0023056 l(1)2Fg lethal (1) 2Fg http://flybase.org/reports/FBgn0023056 - gene - - - "B2/27.14, AS2/11, l(1)2Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011889 tRNA:Lys-CTT-1-2 transfer RNA:Lysine-CTT 1-2 http://flybase.org/reports/FBgn0011889 "FBgn0003795, FBgn0011886, FBgn0050310, FBgn0050517, FBgn0060186" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "35SLys, tRNA[Lys][[2]], AE002769.trna5-LysCTT, tRNA:K2, tRNA:K:CTT:AE002769-c, tRNA:lys2:42Ac, CR30310, CR30517, tRNAlys, chr2R.trna96-LysCTT, tRNA-Lys-CTT-1-2, tRNA:Lys-CTT-1-2, tRNA:K2:42Ac, AAG" - CR30517 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266439 CG45069 - http://flybase.org/reports/FBgn0266439 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45069, CG3419" - CG45069 11-Aug-17 DroID_v2017_08 - Scer\SMP3 - - Mmus\Pigz Hsap\PIGZ viable FBgn0044104 E(rst)C421 E(rst)C421 http://flybase.org/reports/FBgn0044104 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C421, E(rst)C421" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015819 Su(Kr[If]) Suppressor of Kruppel-Irregular facets http://flybase.org/reports/FBgn0015819 - gene - - - Su(Kr[If]) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000594 Est-P Esterase P http://flybase.org/reports/FBgn0000594 FBgn0017620 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay - - "EST7, Est-7, PsiEst-6, EST-5, Est-5, ESTP, EstP, est-P, yEst-6, CG17148, Est-P, yEst6, psiEst-6, Est7" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG17148 11-Aug-17 DroID_v2017_08 "Drer\ces2, Drer\nlgn3b, Drer\cell, Drer\nlgn1, Drer\nlgn3a, Drer\ces3, Drer\nlgn2b, Drer\nlgn4b, Drer\nlgn4a, Drer\si:ch211-93f2.1, Drer\cel.1, Drer\nlgn2a" - "Cele\K07C11.4, Cele\K11G9.1, Cele\T28C12.5, Cele\F15A8.6, Cele\F56C11.6, Cele\T07H6.1, Cele\ges-1, Cele\R173.3, Cele\F13H6.3, Cele\F07C4.12, Cele\Y71H2AM.13, Cele\T28C12.4, Cele\C52A10.2, Cele\B0238.1, Cele\K11G9.2, Cele\K11G9.3, Cele\C52A10.1" "Xtro\nlgn4x, Xtro\LOC100494782, Xtro\cel, Xtro\nlgn3, Xtro\nlgn2, Xtro\ces2, Xtro\ces3" "Mmus\Ces2h, Mmus\Ces2g, Mmus\Nlgn1, Mmus\Cel, Mmus\Ces1f, Mmus\Ces3b, Mmus\Ces2c, Mmus\Ces5a, Mmus\Nlgn3, Mmus\Ces1h, Mmus\Ces4a, Mmus\Ces3a, Mmus\Ces1c, Mmus\Ces2e, Mmus\Ces1d, Mmus\Ces1g, Mmus\Ces2b, Mmus\Nlgn2, Mmus\Ces2a, Mmus\Ces1b, Mmus\Ces1e, Mmus\Ces2f" "Hsap\CES4A, Hsap\CES3, Hsap\CES2, Hsap\CES5A, Hsap\NLGN4Y, Hsap\CES1, Hsap\NLGN2, Hsap\NLGN1, Hsap\NLGN4X, Hsap\NLGN3, Hsap\CEL" " larval stage | late , adult stage " "electrophoretic variant,slow,fast,viable,partially lethal - majority die" FBgn0063378 snoRNA:U31:54Ed snoRNA:U31:54Ed http://flybase.org/reports/FBgn0063378 snoRNA_gene - - - "U31snoRNA, CR32899, snoRNA:U31:54Ed" - CR32899 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031897 CG13784 - http://flybase.org/reports/FBgn0031897 protein_coding_gene - - - "BcDNA:SD10385, CG13784" IPR006603:PQ-loop repeat CG13784 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-246g23.2, Drer\pqlc1, Drer\pqlc2" "Scer\YPQ1, Scer\RTC2, Scer\YDR090C, Scer\YMR010W, Scer\YPQ2" Cele\T19A6.1 "Xtro\pqlc1.1, Xtro\LOC733474, Xtro\pqlc1.2, Xtro\MGC69309" "Mmus\Pqlc1, Mmus\Pqlc2" "Hsap\PQLC2L, Hsap\PQLC2, Hsap\PQLC1" viable FBgn0086474 l(3)d05983 - http://flybase.org/reports/FBgn0086474 gene - - - l(3)d05983 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024856 l(3)96Bf lethal (3) 96Bf http://flybase.org/reports/FBgn0024856 - gene - - - l(3)96Bf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053160 CG33160 - http://flybase.org/reports/FBgn0053160 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP183, CG11531, CG33160" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG33160 11-Aug-17 DroID_v2017_08 "Drer\habp2, Drer\plat, Drer\tmprss4a" - Cele\try-1 - "Mmus\Tmprss4, Mmus\Plat, Mmus\Prss58, Mmus\Gzmk, Mmus\Habp2" "Hsap\HABP2, Hsap\TMPRSS4, Hsap\GZMK, Hsap\PLAT" viable FBgn0026189 prominin-like prominin-like http://flybase.org/reports/FBgn0026189 - protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008795 "bs29e02.y1, CG7740, prominin-like" IPR008795:Prominin CG7740 11-Aug-17 DroID_v2017_08 "Drer\prom2, Drer\prom1b, Drer\prom1a" - Cele\prmn-1 "Xtro\prom1, Xtro\prom2" "Mmus\Prom1, Mmus\Prom2" "Hsap\PROM1, Hsap\PROM2" FBgn0283535 Vha26 Vacuolar H[+]-ATPase 26kD subunit http://flybase.org/reports/FBgn0283535 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR002842 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR002842 apical protein localization ; GO:0045176 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype" "plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD:S000005859" "Vha26, okg, vha26, CG1088, BcDNA.GH03683, anon-83Bb, VhaE, BcDNA:GH03683, vATPase, ATP6V1E1, chr3R:1419698..1419836, oak-gall" "IPR002842:ATPase, V1/A1 complex, subunit E" CG1088 11-Aug-17 DroID_v2017_08 "Drer\atp6v1e1, Drer\atp6v1e1b, Drer\mogat3b" Scer\VMA4 Cele\vha-8 Xtro\atp6v1e1 "Mmus\Atp6v1e1, Mmus\Atp6v1e2" "Hsap\ATP6V1E2, Hsap\ATP6V1E1" "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,embryonic/larval dorsal trunk" FBgn0032491 CG16815 - http://flybase.org/reports/FBgn0032491 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from sequence or structural similarity - - "CG16815, DM27" - CG16815 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036152 CG6175 - http://flybase.org/reports/FBgn0036152 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - "CG6175, anon-WO0257455.23" "IPR006578:MADF domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG6175 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,partially lethal - majority die" FBgn0030094 CG11042 - http://flybase.org/reports/FBgn0030094 protein_coding_gene - - - CG11042 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039749 CG11498 - http://flybase.org/reports/FBgn0039749 protein_coding_gene - cellular response to stress ; GO:0033554 | inferred from electronic annotation with InterPro:IPR026169 mitophagy by induced vacuole formation ; GO:0035695 | inferred from biological aspect of ancestor with PANTHER:PTN001094748 mitochondrial protein catabolic process ; GO:0035694 | inferred from biological aspect of ancestor with PANTHER:PTN001094748 mitochondrial outer membrane ; GO:0005741 | inferred from biological aspect of ancestor with PANTHER:PTN001094748 CG11498 "IPR026169:Mitochondria-eating protein, IPR031981:Mitochondria-eating protein, C-terminal domain" CG11498 11-Aug-17 DroID_v2017_08 - - Cele\F49E10.4 - - - viable DRSC14315 E -0.48285746 0.163927676 3.171273854 0.461518065 0.81556617 0.224525858 FBgn0067379 l(2)309 lethal (2) 309 http://flybase.org/reports/FBgn0067379 gene - - - l(2)309 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0042169 CG18849 - http://flybase.org/reports/FBgn0042169 protein_coding_gene - - - CG18849 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060622 l(3)S088113 lethal (3) S088113 http://flybase.org/reports/FBgn0060622 gene - - - "0881/13, l(3)S088113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261915 l(3)16107 - http://flybase.org/reports/FBgn0261915 gene - - - l(3)16107 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal" FBgn0033316 CG14749 - http://flybase.org/reports/FBgn0033316 protein_coding_gene inositol hexakisphosphate binding ; GO:0000822 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 phospholipid binding ; GO:0005543 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 translation initiation factor binding ; GO:0031369 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 regulation of translational initiation ; GO:0006446 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from sequence or structural similarity with UniProtKB:Q12315 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 regulation of translational termination ; GO:0006449 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q12315 nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with UniProtKB:Q12315 nuclear pore cytoplasmic filaments ; GO:0044614 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 "CG14749, GLE1, Gle1" IPR012476:GLE1-like CG14749 11-Aug-17 DroID_v2017_08 Drer\gle1 Scer\GLE1 - Xtro\gle1 Mmus\Gle1 Hsap\GLE1 viable FBgn0062675 EP2433 EP2433 http://flybase.org/reports/FBgn0062675 gene - - - "EP(2)2433, EP2433" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004147 l(2)57Aa lethal (2) 57Aa http://flybase.org/reports/FBgn0004147 - gene - - - l(2)57Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,recessive" FBgn0043860 pf-6 pairing failure-6 http://flybase.org/reports/FBgn0043860 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG6, pf-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034759 CG13511 - http://flybase.org/reports/FBgn0034759 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13511 IPR006629:LPS-induced tumour necrosis factor alpha factor CG13511 11-Aug-17 DroID_v2017_08 "Drer\litaf, Drer\si:ch211-202h22.7, Drer\cdip1, Drer\si:ch211-202h22.9, Drer\ubald1a, Drer\si:ch211-202h22.8, Drer\si:dkeyp-75b4.8, Drer\si:ch211-157c3.4" - "Cele\F16F9.1, Cele\Y87G2A.19, Cele\B0348.2, Cele\B0348.1, Cele\Y87G2A.18, Cele\Y37D8A.8, Cele\Y22D7AL.15, Cele\Y37D8A.6, Cele\F36G3.3, Cele\Y40H7A.11, Cele\C08E8.1, Cele\Y37D8A.26" "Xtro\cdip1, Xtro\litaf" "Mmus\Litaf, Mmus\Cdip1" "Hsap\LITAF, Hsap\CDIP1" viable FBgn0011664 ms(2)1400 ms(2)1400 http://flybase.org/reports/FBgn0011664 - gene - - - ms(2)1400 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266515 s-562.2 - http://flybase.org/reports/FBgn0266515 gene - - - s-562.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031466 CG3119 - http://flybase.org/reports/FBgn0031466 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 "CG3119, dC1GalT7" IPR003378:Fringe-like CG3119 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-202e17.1, Drer\LOC564281, Drer\c1galt1c1, Drer\c1galt1b, Drer\c1galt1a" - "Cele\Y38C1AB.5, Cele\F56H6.1, Cele\C38H2.2, Cele\W09D10.5, Cele\C17A2.3, Cele\F37A4.3, Cele\bus-4, Cele\E03H4.3, Cele\C02H6.1, Cele\C16D9.6, Cele\T09E11.12, Cele\Y38C1AB.1" "Xtro\LOC100496837, Xtro\c1galt1" "Mmus\C1galt1c1, Mmus\C1galt1" "Hsap\C1GALT1, Hsap\C1GALT1C1" viable FBgn0061089 l(3)S011513a lethal (3) S011513a http://flybase.org/reports/FBgn0061089 gene - - - "0115/13, l(3)S011513a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260600 2L2775 - http://flybase.org/reports/FBgn0260600 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2775 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0039024 CG4721 - http://flybase.org/reports/FBgn0039024 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497 compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype" - "anon-EST:Posey132, CG4721" "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG4721 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\phex, Drer\ece2b, Drer\mmel1" - "Cele\nep-7, Cele\nep-20, Cele\nep-24, Cele\nep-18, Cele\nep-23, Cele\nep-5, Cele\nep-3, Cele\nep-8, Cele\nep-13, Cele\nep-12, Cele\nep-19, Cele\nep-6, Cele\nep-17, Cele\nep-10, Cele\nep-9, Cele\nep-21, Cele\nep-26, Cele\nep-16" "Xtro\ece2, Xtro\ece1, Xtro\ecel1, Xtro\mmel1" "Mmus\Ecel1, Mmus\Ece1, Mmus\Kel, Mmus\Mme, Mmus\Mmel1, Mmus\Phex, Mmus\Ece2" "Hsap\ECE1, Hsap\ECEL1, Hsap\MME, Hsap\PHEX, Hsap\MMEL1, Hsap\KEL, Hsap\ECE2" visible eye FBgn0054030 CG34030 - http://flybase.org/reports/FBgn0054030 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1084, HDC08855, CG34030" - CG34030 11-Aug-17 DroID_v2017_08 - - Cele\xbx-6 - - - FBgn0022730 l(2)PGM-21 lethal (2) PGM-21 http://flybase.org/reports/FBgn0022730 - gene - - - "PGM-21, l(2)PGM-21" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014257 l(2)FE3 lethal (2) FE3 http://flybase.org/reports/FBgn0014257 - gene - - - "FE3, l(2)FE3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002582 M(1)5A Minute (1) 5A http://flybase.org/reports/FBgn0002582 - gene - - - M(1)5A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032940 Mondo Mondo http://flybase.org/reports/FBgn0032940 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with MGI:MGI:1927999 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 transcription factor binding ; GO:0008134 | inferred from sequence or structural similarity with MGI:MGI:1927999 DNA binding ; GO:0003677 | contributes_to inferred from sequence or structural similarity with MGI:MGI:1927999" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with Max glucose homeostasis ; GO:0042593 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:1927999 response to sucrose ; GO:0009744 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGI:MGI:1927999 "154826_at, CG18362, dmondo, anon-39Da, Mondo, bHLHd12, Mio, mio, ChREBP, mlx, mondo" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG18362 11-Aug-17 DroID_v2017_08 "Drer\mlxip, Drer\LOC100535945" - "Cele\mxl-2, Cele\mml-1" Xtro\mlxip "Mmus\Mlxip, Mmus\Mlxipl" "Hsap\MLXIPL, Hsap\MLXIP" "lethal,recessive,feeding behavior defective,viable,fertile,developmental rate defective,conditional,partially lethal,lethal - all die during larval stage,chemical conditional,stress response defective,chemical sensitive,small body" DRSC02668 IEK -1.692120041 -1.219683889 -1.303151459 -1.73792302 -0.136675375 -1.661653564 FBgn0266414 CR45054 - http://flybase.org/reports/FBgn0266414 non_protein_coding_gene - - - "CG45054, CR45054" - CR45054 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039224 CG13634 - http://flybase.org/reports/FBgn0039224 protein_coding_gene - - - CG13634 - CG13634 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011593 fs(3)2877 fs(3)2877 http://flybase.org/reports/FBgn0011593 - gene - - - fs(3)2877 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" egg FBgn0025791 Su(var)b601 Suppressor of variegation b601 http://flybase.org/reports/FBgn0025791 - gene - - - "Su-var(2)b601, Su(var)b601" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259166 CG42271 - http://flybase.org/reports/FBgn0259166 protein_coding_gene "phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity ; GO:0016316 | inferred from biological aspect of ancestor with PANTHER:PTN000257020" signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000257020 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000257020 "CG42271, CG33248, CG1846, CG33249, INPP4A, FBgn0259166" "IPR000008:C2 domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG42271 11-Aug-17 DroID_v2017_08 "Drer\inpp4ab, Drer\inpp4aa, Drer\inpp4b" - Cele\R01H10.7 Xtro\inpp4a "Mmus\Inpp4b, Mmus\Inpp4a, Mmus\Prex2" "Hsap\INPP4A, Hsap\INPP4B, Hsap\PREX2" FBgn0040185 l(1)G0226 lethal (1) G0226 http://flybase.org/reports/FBgn0040185 gene - - - l(1)G0226 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,chaeta" FBgn0033981 Cyp6a21 Cyp6a21 http://flybase.org/reports/FBgn0033981 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "cyp6a21, 6a21, CG10247, Cyp6a21" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10247 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp3c1, Drer\cyp4v8, Drer\tbxas1, Drer\cyp4f3, Drer\cyp3c2, Drer\cyp4v7, Drer\cyp3c3, Drer\cyp4t8, Drer\cyp3c4" Scer\ERG11 "Cele\cyp-25A4, Cele\cyp-13A11, Cele\cyp-32A1, Cele\cyp-13B2, Cele\cyp-25A3, Cele\cyp-42A1, Cele\cyp-25A1, Cele\cyp-29A4, Cele\cyp-25A6, Cele\cyp-44A1, Cele\cyp-13A10, Cele\cyp-13A4, Cele\cyp-43A1, Cele\cyp-31A2, Cele\cyp-13A12, Cele\cyp-31A3, Cele\cyp-13A5, Cele\cyp-13A7, Cele\cyp-13A2, Cele\cyp-29A3, Cele\cyp-25A2, Cele\cyp-32B1, Cele\cyp-13A3, Cele\cyp-13A6, Cele\cyp-37B1, Cele\cyp-29A2, Cele\cyp-13A8, Cele\cyp-13A1, Cele\cyp-13B1" "Xtro\LOC100494419, Xtro\tbxas1, Xtro\cyp3a5, Xtro\cyp3a4" "Mmus\Cyp4f18, Mmus\Cyp4f37, Mmus\Cyp3a41a, Mmus\Cyp4a14, Mmus\Cyp3a44, Mmus\Cyp4f16, Mmus\Cyp4a31, Mmus\Cyp4a10, Mmus\Cyp3a11, Mmus\Cyp3a13, Mmus\Cyp3a41b, Mmus\Tbxas1, Mmus\Cyp3a57, Mmus\Cyp4b1, Mmus\Cyp3a59, Mmus\Cyp20a1, Mmus\Cyp4f39, Mmus\Cyp4v3, Mmus\Cyp4f13, Mmus\Cyp4a32, Mmus\Cyp4a12b, Mmus\Cyp3a25, Mmus\Cyp4a12a, Mmus\Cyp3a16, Mmus\Cyp4f14, Mmus\Cyp4f15" "Hsap\CYP4F8, Hsap\CYP3A43, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4B1, Hsap\CYP4F12, Hsap\CYP3A4, Hsap\CYP4V2, Hsap\CYP3A7, Hsap\CYP4X1, Hsap\TBXAS1, Hsap\CYP3A5, Hsap\CYP4Z1, Hsap\CYP4F3, Hsap\CYP20A1, Hsap\CYP4F2, Hsap\CYP4A11, Hsap\CYP4F11, Hsap\CYP4F22, Hsap\CYP4A22" viable FBgn0037172 ND-B14.5AL NADH dehydrogenase (ubiquinone) B14.5 A subunit-like http://flybase.org/reports/FBgn0037172 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR009947 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from biological aspect of ancestor with PANTHER:PTN000968153" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000968153 "CG6914, BcDNA:AT13913, N4AM, ND-B14.5AL" IPR009947:NADH:ubiquinone oxidoreductase subunit B14.5a CG6914 11-Aug-17 DroID_v2017_08 Drer\ndufa7 - Cele\F45H10.3 - Mmus\Ndufa7 Hsap\NDUFA7 viable FBgn0263505 CR43494 - http://flybase.org/reports/FBgn0263505 non_protein_coding_gene - - - CR43494 - CR43494 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034070 SP2353 SP2353 http://flybase.org/reports/FBgn0034070 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881 molecular_function ; GO:0003674 | no biological data available negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg extracellular space ; GO:0005615 | inferred from sequence or structural similarity with eys "CT18665, CG8403, BcDNA:GH12319, SP2353" "IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001881:EGF-like calcium-binding domain" CG8403 11-Aug-17 DroID_v2017_08 "Drer\egflam, Drer\hspg2, Drer\lama4, Drer\sid4, Drer\LOC101884253, Drer\agrn" - "Cele\T19D12.6, Cele\agr-1, Cele\unc-52" "Xtro\LOC100491172, Xtro\egflam, Xtro\agrn, Xtro\hspg2" "Mmus\Hspg2, Mmus\Agrn, Mmus\Egflam" "Hsap\AGRN, Hsap\HSPG2, Hsap\EYS, Hsap\EGFLAM" viable FBgn0028157 l(3)S041919 lethal (3) S041919 http://flybase.org/reports/FBgn0028157 gene - - - "0419/19, l(3)S041919" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0038275 CG3817 - http://flybase.org/reports/FBgn0038275 protein_coding_gene - maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000326640 maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000326640 neurogenesis ; GO:0022008 | inferred from mutant phenotype "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000326640" "CG3817, RRP15" IPR012459:Ribosomal RNA-processing protein 15 CG3817 11-Aug-17 DroID_v2017_08 Drer\rrp15 Scer\RRP15 Cele\F53E10.6 - Mmus\Rrp15 Hsap\RRP15 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC15515 K -0.016082646 0.032359987 0.455390794 -0.105585825 -1.899419552 0.385474073 FBgn0040484 BobD Brother of Brd D http://flybase.org/reports/FBgn0040484 gene - - - "Bob, BobD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020822 l(3)98Dh lethal (3) 98Dh http://flybase.org/reports/FBgn0020822 - gene - - - "M315, l(3)98Dh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020565 anon-EB8 anon-EB8 http://flybase.org/reports/FBgn0020565 - gene - - - anon-EB8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001195 His1 Histone H1 http://flybase.org/reports/FBgn0001195 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "negative regulation of histone modification ; GO:0031057 | inferred from direct assay chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR005818 condensed nuclear chromosome ; GO:0000794 |" "H1, HisC, H1A, hisl, DmeH1, His1, histone, his, dH1" "IPR005818:Linker histone H1/H5, domain H15, IPR005819:Histone H5, IPR011991:Winged helix-turn-helix DNA-binding domain" - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "polytene chromosomeda.G32,polytene chromosome chromocenterda.G32" FBgn0013584 l(3)92Ea lethal (3) 92Ea http://flybase.org/reports/FBgn0013584 - gene - - - "AS416, l(3)92Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040089 meso18E meso18E http://flybase.org/reports/FBgn0040089 protein_coding_gene - mesoderm development ; GO:0007498 | inferred from expression pattern - "Meso18E, ld26007, Dmeso18E, Mmeso18E, eso18E, anon-18DEd, CG14233, meso18E" - CG14233 11-Aug-17 DroID_v2017_08 Drer\si:ch211-116o3.5 - - - - - "viable,fertile" FBgn0263738 Ada2a transcriptional Adaptor 2a http://flybase.org/reports/FBgn0263738 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000271860" histone H4 acetylation ; GO:0043967 | inferred from direct assay positive regulation of histone acetylation ; GO:0035066 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 histone acetylation ; GO:0016573 | inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 chromatin remodeling ; GO:0006338 | inferred from direct assay SAGA-type complex ; GO:0070461 | inferred from biological aspect of ancestor with PANTHER:PTN000271862 transcriptionally active chromatin ; GO:0035327 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG43663, dAda2a, Ada2a, Ada2A, CG7150, CG31318, CG33520, dAda2A, ada2a, ADA2a, dADA2a, DmADA2a, DmAda2a" "IPR016827:Transcriptional adaptor 2, IPR009057:Homeobox domain-like, IPR007526:SWIRM domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG43663 11-Aug-17 DroID_v2017_08 "Drer\tada2b, Drer\tada2a, Drer\polr2d" "Scer\YOR338W, Scer\ADA2, Scer\FUN19, Scer\RPB4" "Cele\ada-2, Cele\rpb-4" "Xtro\tada2a, Xtro\polr2d, Xtro\tada2b" "Mmus\Tada2b, Mmus\Polr2d, Mmus\Tada2a" "Hsap\TADA2A, Hsap\POLR2D, Hsap\TADA2B" "lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable,lethal" FBgn0010772 Xe7 Xe7 http://flybase.org/reports/FBgn0010772 FBgn0037362 protein_coding_gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(3)02248, CG2179, Xe7" - CG2179 11-Aug-17 DroID_v2017_08 Drer\akap17a - Cele\cux-7 Xtro\akap17a Mmus\Akap17b Hsap\AKAP17A "lethal,neuroanatomy defective,somatic clone,recessive,viable,visible" "chaeta,supernumerary" FBgn0029502 COQ7 COQ7 http://flybase.org/reports/FBgn0029502 protein_coding_gene - oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR011566 ubiquinone biosynthetic process ; GO:0006744 | inferred from electronic annotation with InterPro:IPR011566 - "Dclk1, CG14437, COQ7" "IPR009078:Ferritin-like superfamily, IPR011566:Ubiquinone biosynthesis protein Coq7, IPR012347:Ferritin-related" CG14437 11-Aug-17 DroID_v2017_08 Drer\coq7 Scer\CAT5 Cele\clk-1 Xtro\coq7 Mmus\Coq7 Hsap\COQ7 "developmental rate defective,RU486 conditional,short lived,female,viable" FBgn0011981 tRNA:Ser-AGA-3-2 transfer RNA:Serine-AGA 3-2 http://flybase.org/reports/FBgn0011981 "FBgn0003830, FBgn0011968, FBgn0052618, FBgn0060070" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "774-2, Ser-tRNA-4-7, AE002593.trna9-SerAGA, tRNA:S:AGA:AE002593-b, CR32618, tRNA:ser, tRNA:S, tRNA:ser774:12Ef, tRNA[[Ser]], chrX.trna13-SerAGA, tRNA-Ser-AGA-3-2, tRNA:Ser-AGA-3-2, tRNA:S774:12Ef, UCU" - CR32618 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014113 anon-84Bb anon-84Bb http://flybase.org/reports/FBgn0014113 - gene - - - "Y3, anon-84Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage&&larval stage&&pupal stage , adult stage && oogenesis stage " unfertilized egg

FBgn0001919 l(2)25Bf lethal (2) 25Bf http://flybase.org/reports/FBgn0001919 - gene - - - "jf15, l(2)jf15, l(2)25Bf" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003916 snRNA:U1:21D small nuclear RNA U1 at 21D http://flybase.org/reports/FBgn0003916 "FBgn0003915, FBgn0026794, FBgn0051656" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity "snRNA:U1, U1, U1 snRNA, U1a-21D, U1a1(AT)[[15]], U1-21.1, U1snRNA, U1a, U1-1, U1 21D, U14, K5, dU1, snRNA1, snRNA-U1-21.1, U1snRNA21D, CR31656, snRNA:U1:21D, U1:21D, U1-21D, 21E U1" - CR31656 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052553 CR32553 - http://flybase.org/reports/FBgn0052553 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32553, CR32553" - CR32553 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039688 Kul Kuzbanian-like http://flybase.org/reports/FBgn0039688 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from direct assay membrane protein ectodomain proteolysis ; GO:0006509 | inferred from sequence or structural similarity with HGNC:195 regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype membrane protein ectodomain proteolysis ; GO:0006509 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:195 "ADAM10, CT3146, CG1964, Kul, kul" "IPR001590:Peptidase M12B, ADAM/reprolysin, IPR001762:Disintegrin domain, IPR024079:Metallopeptidase, catalytic domain, IPR034025:ADAM10/ADAM17 catalytic domain, IPR002870:Peptidase M12B, propeptide" CG1964 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-396h14.1, Drer\adam10a, Drer\adam17a, Drer\adam10b, Drer\adam17b" - Cele\sup-17 "Xtro\adam17, Xtro\adam10" "Mmus\Adam17, Mmus\Adam10" "Hsap\ADAM10, Hsap\ADAM17" "visible,partially lethal - majority die,some die during pupal stage" "wing,wing margin,wing vein,wing hair,supernumerary,interfollicle cell,trichogen cell,mesothoracic tergum" FBgn0036911 Fibp Fibp http://flybase.org/reports/FBgn0036911 protein_coding_gene fibroblast growth factor binding ; GO:0017134 | inferred from electronic annotation with InterPro:IPR008614 - - "CG8660, DrFIBP, Fibp, F1bp" IPR008614:Acidic fibroblast growth factor intracellular-binding protein CG8660 11-Aug-17 DroID_v2017_08 "Drer\fibpa, Drer\fibpb" - Cele\fbxa-135 Xtro\fibp Mmus\Fibp Hsap\FIBP "viable,fertile" FBgn0061188 Yu Yu http://flybase.org/reports/FBgn0061188 non_protein_coding_gene - - - "Yu, CR42645, yu" - CR42645 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083952 CG34116 - http://flybase.org/reports/FBgn0083952 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14103, CG34116" "IPR003656:Zinc finger, BED-type" CG34116 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036563 CG13075 - http://flybase.org/reports/FBgn0036563 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG13075 IPR002557:Chitin binding domain CG13075 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0062577 Mod(var)E1060 Mod(var)E1060 http://flybase.org/reports/FBgn0062577 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1060, Mod(var)E1060" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0001703 l(1)ESHS24 lethal (1) ESHS24 http://flybase.org/reports/FBgn0001703 - gene - - - l(1)ESHS24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037163 laza lazaro http://flybase.org/reports/FBgn0037163 protein_coding_gene phosphatidate phosphatase activity ; GO:0008195 | non-traceable author statement phosphatidate phosphatase activity ; GO:0008195 | inferred from sequence or structural similarity with HGNC:9228 phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000017950 lipid phosphatase activity ; GO:0042577 | inferred from biological aspect of ancestor with PANTHER:PTN000807400 dephosphorylation ; GO:0016311 | non-traceable author statement thermotaxis ; GO:0043052 | inferred from direct assay phototransduction ; GO:0007602 | inferred from mutant phenotype inferred from genetic interaction with rdgB inferred from genetic interaction with rdgA phospholipid metabolic process ; GO:0006644 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 response to light intensity ; GO:0009642 | inferred from mutant phenotype phospholipid dephosphorylation ; GO:0046839 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 phototransduction ; GO:0007602 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:9228 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 "WUN-like, laza, Laza, CG11440, LPP-like, LPP" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG11440 11-Aug-17 DroID_v2017_08 "Drer\plpp2b, Drer\plppr4a, Drer\plpp4, Drer\plppr1, Drer\plppr2b, Drer\plppr2a, Drer\LOC794598, Drer\ppap2d, Drer\plppr5a, Drer\plpp1a, Drer\plpp3, Drer\plppr3a, Drer\plppr3b, Drer\plpp2a, Drer\plppr5b, Drer\LOC571722, Drer\plpp5" "Scer\LPP1, Scer\DPP1" "Cele\T28D9.3, Cele\F53C3.13, Cele\T06D8.3, Cele\F13E6.5" "Xtro\plpp4, Xtro\plpp3, Xtro\plpp5, Xtro\plpp1, Xtro\LOC100135382, Xtro\plpp2" "Mmus\Plpp2, Mmus\Plppr2, Mmus\Plpp1, Mmus\Plppr1, Mmus\Plpp5, Mmus\Plpp3, Mmus\Plppr3, Mmus\Plppr5, Mmus\Plpp4, Mmus\Plppr4" "Hsap\PLPPR2, Hsap\PLPPR1, Hsap\PLPP2, Hsap\PLPPR5, Hsap\PLPP3, Hsap\PLPP4, Hsap\PLPP5, Hsap\PLPPR4, Hsap\PLPP1, Hsap\PLPPR3" "neurophysiology defective,viable,fertile,thermotaxis behavior defective" "eye,rhabdomere" FBgn0052279 Drsl2 Drosomycin-like 2 http://flybase.org/reports/FBgn0052279 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs defense response to protozoan ; GO:0042832 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro2, CT30310, Dro-D, CG10813, CG32279, Drs-lD, dro2, Drsl2, dmy2, dro-2" "IPR003614:Knottin, scorpion toxin-like" CG32279 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08160 K 0.124052137 -0.889620755 0.224185389 -0.515382324 0.292733133 1.710552507 FBgn0015427 l(1)1Fg lethal (1) 1Fg http://flybase.org/reports/FBgn0015427 - gene - - - "D42, 4-134, l(1)1Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259193 Ir94d Ionotropic receptor 94d http://flybase.org/reports/FBgn0259193 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG17379, DmelIR94d, CG42297, Ir94d, IR94d" - CG42297 11-Aug-17 DroID_v2017_08 - - Cele\glr-7 - - - FBgn0028670 Vha100-2 Vacuolar H[+] ATPase 100kD subunit 2 http://flybase.org/reports/FBgn0028670 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000005796" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence or structural similarity with SGD:S000005796 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 "plasma membrane ; GO:0005886 | inferred from direct assay vacuolar proton-transporting V-type ATPase complex ; GO:0016471 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000005796 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype" "CG7679, vha100-2, CG18617, BcDNA:LD21735, anon-WO0118547.296, Vha100-2" "IPR002490:V-type ATPase, V0 complex, 116kDa subunit family, IPR026028:ATPase, V0 complex, subunit 116kDa, eukaryotic" CG18617 11-Aug-17 DroID_v2017_08 "Drer\atp6v0a2a, Drer\atp6v0a1b, Drer\tcirg1b, Drer\atp6v0a1a, Drer\atp6v0a2b, Drer\si:ch73-173p19.2, Drer\tcirg1a" "Scer\STV1, Scer\VPH1" "Cele\vha-6, Cele\vha-7, Cele\vha-5, Cele\unc-32" "Xtro\atp6v0a1, Xtro\atp6v0a2, Xtro\atp6v0a4, Xtro\tcirg1" "Mmus\Atp6v0a4, Mmus\Atp6v0a1, Mmus\Tcirg1, Mmus\Atp6v0a2" "Hsap\TCIRG1, Hsap\ATP6V0A4, Hsap\ATP6V0A2, Hsap\ATP6V0A1" "viable,lethal,recessive,fertile,visible" "chaeta,supernumerary" FBgn0259387 C255 - http://flybase.org/reports/FBgn0259387 gene - - - C255 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing hair,chaeta" FBgn0005303 Mot-K Mottled K http://flybase.org/reports/FBgn0005303 - gene - - - "Mo[K], Mot-K" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" eye FBgn0050050 CG30050 - http://flybase.org/reports/FBgn0050050 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG30050 IPR010512:Protein of unknown function DUF1091 CG30050 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262896 CG43251 - http://flybase.org/reports/FBgn0262896 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43251, lincRNA.639" - CG43251 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052324 tRNA:Glu-CTC-3-7 transfer RNA:Glutamic acid-CTC 3-7 http://flybase.org/reports/FBgn0052324 tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "AE002584.trna9-GluCTC, tRNA:E:CTC:AE002584-g, CR32324, chr3L.trna9-GluCTC, tRNA:Glu-CTC-3-7, tRNA:CR32324, tRNA-Glu-CTC-3-7, GAG" - CR32324 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067088 J18 J18 http://flybase.org/reports/FBgn0067088 gene - - - J18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,viable" eye FBgn0259435 EP-767.1 - http://flybase.org/reports/FBgn0259435 gene - - - EP-767.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0267541 CR45881 - http://flybase.org/reports/FBgn0267541 non_protein_coding_gene - - - CR45881 - CR45881 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264393 CG43841 - http://flybase.org/reports/FBgn0264393 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43841, CG32551" - CG43841 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010933 l(3)09143 lethal (3) 09143 http://flybase.org/reports/FBgn0010933 - gene - - - "l(3)9143, l(3)09143" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067905 IM14 Immune induced molecule 14 http://flybase.org/reports/FBgn0067905 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response ; GO:0006952 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay "CG33990, DIM 14, IM14, im14" - CG33990 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264539 CR43918 - http://flybase.org/reports/FBgn0264539 non_protein_coding_gene - - - CR43918 - CR43918 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005298 mei-G17 meiotic G17 http://flybase.org/reports/FBgn0005298 - gene - - - mei-G17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive" meiosis I FBgn0035287 CG13937 - http://flybase.org/reports/FBgn0035287 protein_coding_gene "sulfotransferase activity ; GO:0008146 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR018011" carbohydrate biosynthetic process ; GO:0016051 | inferred from electronic annotation with InterPro:IPR018011 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR018011" "CG13937, d4ST2" "IPR005331:Sulfotransferase, IPR018011:Carbohydrate sulfotransferase 8-10, IPR015943:WD40/YVTN repeat-like-containing domain" CG13937 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-26i13.3, Drer\si:dkey-26i13.4, Drer\si:dkey-26i13.7, Drer\LOC100536144, Drer\chst11, Drer\si:dkey-26i13.6, Drer\chst12b, Drer\chst8, Drer\chst12a, Drer\si:ch211-236h17.3, Drer\si:dkey-26i13.5, Drer\si:ch211-269c21.2, Drer\chst10" - - Xtro\chst8 "Mmus\Chst13, Mmus\Chst8, Mmus\Chst12, Mmus\Chst11, Mmus\Chst9, Mmus\Chst10" "Hsap\CHST12, Hsap\CHST8, Hsap\CHST11, Hsap\CHST13, Hsap\CHST10, Hsap\CHST9" viable FBgn0260078 2L3651 - http://flybase.org/reports/FBgn0260078 gene - - - 2L3651 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0036183 CG6083 - http://flybase.org/reports/FBgn0036183 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471 mushroom body development ; GO:0016319 | inferred from mutant phenotype" - CG6083 "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG6083 11-Aug-17 DroID_v2017_08 "Drer\zgc:110782, Drer\si:dkey-180p18.9, Drer\akr1a1b, Drer\zgc:56622, Drer\zgc:110366, Drer\zgc:101765, Drer\akr1b1, Drer\akr1a1a" "Scer\ARA1, Scer\GCY1, Scer\GRE3, Scer\YPR1, Scer\YDL124W, Scer\YJR096W" "Cele\T08H10.1, Cele\ZK1290.5, Cele\F53F1.2, Cele\Y39G8B.1, Cele\C56G3.2, Cele\F53F1.3, Cele\ZC443.1, Cele\C35D10.6, Cele\K07C5.2, Cele\C01G5.5, Cele\C07D8.6, Cele\Y39G8B.2" "Xtro\akr1c1, Xtro\akr1c2, Xtro\LOC548351, Xtro\akr1a1, Xtro\akr1d1, Xtro\akr1c8p, Xtro\akr1b1" "Mmus\Akr1b10, Mmus\Akr1cl, Mmus\Akr1c6, Mmus\Akr1e1, Mmus\Akr1c12, Mmus\Akr1c20, Mmus\Akr1b7, Mmus\Akr1c19, Mmus\Akr1a1, Mmus\Akr1b3, Mmus\Akr1c14, Mmus\Akr1c21, Mmus\Akr1c18, Mmus\Akr1d1, Mmus\Akr1c13, Mmus\Akr1b8" "Hsap\AKR1B10, Hsap\AKR1B1, Hsap\AKR1C4, Hsap\AKR1B15, Hsap\AKR1E2, Hsap\AKR1C2, Hsap\AKR1C1, Hsap\AKR1D1, Hsap\AKR1C3, Hsap\AKR1A1" "neuroanatomy defective,viable" adult mushroom body DRSC24586 K 0.364844955 -0.05629393 0.593022292 0.681049727 -0.298706111 -1.597114604 FBgn0001808 l(1)Mc56 lethal (1) Mc56 http://flybase.org/reports/FBgn0001808 - gene - - - l(1)Mc56 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone" FBgn0020788 rABP70 ribosomal 'Alu-repeat' binding protein 70 http://flybase.org/reports/FBgn0020788 - gene - - - rABP70 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016026 l(3)89Ce lethal (3) 89Ce http://flybase.org/reports/FBgn0016026 - gene - - - l(3)89Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265426 CR44338 - http://flybase.org/reports/FBgn0265426 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44338, CR44338" - CR44338 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016069 slinky slinky http://flybase.org/reports/FBgn0016069 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available slinky - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050045 Cpr49Aa Cuticular protein 49Aa http://flybase.org/reports/FBgn0050045 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG8496, Cpr49Aa, CG30045, DmelCpr49Aa" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG30045 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0011151 l(1)Q227 lethal (1) Q227 http://flybase.org/reports/FBgn0011151 FBgn0010210 gene - - - l(1)Q227 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038880 SIFaR SIFamide receptor http://flybase.org/reports/FBgn0038880 protein_coding_gene neuropeptide Y receptor activity ; GO:0004983 | inferred from electronic annotation with InterPro:IPR000611 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model neuropeptide receptor activity ; GO:0008188 | inferred from physical interaction with SIFa G-protein coupled peptide receptor activity ; GO:0008528 | inferred from sequence or structural similarity "mating behavior, sex discrimination ; GO:0048047 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay "SIFR, CG10823, anon-WO0170980.44, anon-WO0170980.43, DrmSIFR, SIF-R, SIFa-R, SIFaR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000611:Neuropeptide Y receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG10823 11-Aug-17 DroID_v2017_08 "Drer\prlh2r, Drer\ccr7, Drer\si:dkey-211g8.1, Drer\cxcr4b, Drer\sc:d217, Drer\igsf9ba, Drer\ackr3a, Drer\npffr1l1, Drer\xcr1b.1, Drer\si:dkey-117a8.1, Drer\cxcr2, Drer\LOC793148, Drer\ccdc141, Drer\ccr8.1, Drer\si:ch73-160i9.3, Drer\ccr12b.1, Drer\ccr9b, Drer\cntn1a, Drer\npffr1l2, Drer\ackr4a, Drer\igsf9bb, Drer\LOC101884253, Drer\cxcr4a, Drer\zgc:194312, Drer\LOC100535965, Drer\ccr12a, Drer\npffr1l3, Drer\LOC103908669, Drer\cntn1b, Drer\LOC561565, Drer\cabz01093075.1, Drer\neo1a, Drer\ccr12b.2, Drer\npffr2a, Drer\LOC100006764, Drer\LOC797181, Drer\si:ch211-207g17.3, Drer\cntn2, Drer\ccr6a, Drer\si:dkey-202l22.3, Drer\xcr1a.1, Drer\ccr9a, Drer\LOC100151078, Drer\si:ch73-160i9.1, Drer\si:ch211-240b21.5, Drer\si:dkey-42l23.7, Drer\npy7r, Drer\si:dkey-42l23.5, Drer\ackr3b, Drer\LOC793479, Drer\xcr1b.2, Drer\ackr4b, Drer\si:ch211-171h4.6, Drer\cmklr1" - "Cele\npr-22, Cele\npr-35, Cele\ckr-1, Cele\tkr-3, Cele\npr-11" "Xtro\LOC100491949, Xtro\npffr2" "Mmus\Ccr3, Mmus\Cx3cr1, Mmus\Ccr1l1, Mmus\Ackr3, Mmus\Ccr10, Mmus\Cntn2, Mmus\Ackr4, Mmus\Ackr2, Mmus\Cntn1, Mmus\Npffr1, Mmus\Ccr5, Mmus\Cxcr2, Mmus\Cxcr6, Mmus\Neo1, Mmus\Ccr4, Mmus\Dcc, Mmus\Cxcr5, Mmus\Ccr8, Mmus\Igsf9b, Mmus\Ccr9, Mmus\Ccr6, Mmus\Xcr1, Mmus\Cxcr4, Mmus\Npffr2, Mmus\Ccdc141, Mmus\Cxcr1, Mmus\Ccr1, Mmus\Ccr2, Mmus\Ccr7, Mmus\Cxcr3, Mmus\Ccrl2, Mmus\Cmklr1" "Hsap\CNTN2, Hsap\CXCR4, Hsap\CCDC141, Hsap\CCR7, Hsap\CCR10, Hsap\NPFFR1, Hsap\ACKR3, Hsap\CNTN1, Hsap\XCR1, Hsap\CCR9, Hsap\CCR3, Hsap\NPFFR2, Hsap\CXCR1, Hsap\CCR8, Hsap\CMKLR1, Hsap\CCR5, Hsap\CX3CR1, Hsap\ACKR4, Hsap\CCR1, Hsap\ACKR2, Hsap\CCR2, Hsap\CCR4, Hsap\IGSF9B, Hsap\CXCR2, Hsap\DCC, Hsap\CXCR3, Hsap\CXCR5, Hsap\CXCR6, Hsap\CCR6, Hsap\NEO1, Hsap\CCRL2" "long lived,viable" FBgn0264410 FCE-C - http://flybase.org/reports/FBgn0264410 gene - - - FCE-C - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,somatic clone" FBgn0031673 CG31650 - http://flybase.org/reports/FBgn0031673 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG9112, CG31650, RCN2" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG31650 11-Aug-17 DroID_v2017_08 "Drer\rcn2, Drer\calua, Drer\rcn1, Drer\rcn3" - "Cele\calu-2, Cele\calu-1" "Xtro\rcn2, Xtro\calu, Xtro\rcn3, Xtro\rcn1" "Mmus\Rcn1, Mmus\Rcn3, Mmus\Rcn2, Mmus\Calu" "Hsap\RCN2, Hsap\RCN1, Hsap\RCN3, Hsap\CALU" viable FBgn0050130 CG30130 - http://flybase.org/reports/FBgn0050130 protein_coding_gene - - - CG30130 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263764 CR43681 - http://flybase.org/reports/FBgn0263764 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Dm_2L:52920, lincRNA.108, CR43681, CG43681" - CR43681 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010189 tu-47 tu-47 http://flybase.org/reports/FBgn0010189 - gene - - - tu-47 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266003 CR44777 - http://flybase.org/reports/FBgn0266003 non_protein_coding_gene - - - CR44777 - CR44777 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002323 l(3)86Fb lethal (3) 86Fb http://flybase.org/reports/FBgn0002323 - gene - - - "l(3)ck2, l(3)86Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0261671 tweek tweek http://flybase.org/reports/FBgn0261671 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "tweek, CG4841, CG15133, CG15134, CG42555, CG42706, Tweek" "IPR018863:Fragile site-associated protein, C-terminal, IPR033616:Protein KIAA1109" CG42555 11-Aug-17 DroID_v2017_08 Drer\si:ch211-233a24.2 Scer\CSF1 Cele\lpd-3 Xtro\kiaa1109 Mmus\4932438A13Rik Hsap\KIAA1109 FBgn0036168 CG7512 - http://flybase.org/reports/FBgn0036168 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "transcription, DNA-templated ; GO:0006351 | inferred from biological aspect of ancestor with PANTHER:PTN000278753 regulation of neuron differentiation ; GO:0045664 | inferred from biological aspect of ancestor with PANTHER:PTN000278753" - CG7512 IPR013087:Zinc finger C2H2-type CG7512 11-Aug-17 DroID_v2017_08 Drer\casz1 - - - Mmus\Casz1 Hsap\CASZ1 viable FBgn0037992 CG4702 - http://flybase.org/reports/FBgn0037992 protein_coding_gene - - - "CG4702, 4702" IPR006631:Protein of unknown function DM4/12 CG4702 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0039722 Capa Capability http://flybase.org/reports/FBgn0039722 protein_coding_gene myostimulatory hormone activity ; GO:0016084 | inferred from mutant phenotype neuropeptide hormone activity ; GO:0005184 | inferred from mutant phenotype receptor binding ; GO:0005102 | inferred from sequence or structural similarity neuropeptide hormone activity ; GO:0005184 | non-traceable author statement diuretic hormone activity ; GO:0008613 | inferred from direct assay neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with PK1-R neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with CapaR epithelial fluid transport ; GO:0042045 | inferred from direct assay cation transport ; GO:0006812 | traceable author statement neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern neuropeptide signaling pathway ; GO:0007218 | inferred from sequence or structural similarity positive regulation of cytosolic calcium ion concentration ; GO:0007204 | inferred from direct assay nitric oxide-cGMP-mediated signaling pathway ; GO:0038060 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CAP[[2b]], capa-1, capa-2, capa-3, Drm-PK-1, CAP2b-3, CG15520, Drm-PVK-2, Drm-PVK-1, CAP2B-3, CAP2B-2, CAP2B-1, Drm-CAP-2, Drm-CAP-1, CAP2b, CAP2b-2, CAP2b-1, pyrokinin/PBAN-like, CAP2B/pyrokinin, Drm-MT, Drm-CAP2b/MT, Cap-2b, CAP-2b, Capa-1, Capa-2, CAPA, Drm-PVK, CAP, Capa, capa, capa 2, Cap-1, Cap-2, Cap-3, Drm-capa-1, PVK-2, Drm-PK, CAPA-PVK/PK, CAPA-PVK-1, CAPA-PVK-2, CAPA-PK, CPPB, Drome-capa-1" - CG15520 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051858 t-cup tetleys-cup http://flybase.org/reports/FBgn0051858 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000031653 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 "t-cup, CG31858, cup" IPR001199:Cytochrome b5-like heme/steroid binding domain CG31858 11-Aug-17 DroID_v2017_08 "Drer\pgrmc2, Drer\pgrmc1, Drer\nenf" Scer\DAP1 Cele\vem-1 "Xtro\pgrmc1, Xtro\nenf, Xtro\pgrmc2" "Mmus\Pgrmc2, Mmus\Pgrmc1, Mmus\Nenf" "Hsap\NENF, Hsap\PGRMC1, Hsap\PGRMC2" viable DRSC01254 I 1.741319522 1.652263905 0.622614721 1.084253099 -0.24252598 -0.043542791 FBgn0038145 Droj2 DnaJ-like-2 http://flybase.org/reports/FBgn0038145 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012724 unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001305, InterPro:IPR008971, InterPro:IPR012724 heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001305" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971, InterPro:IPR012724 response to heat ; GO:0009408 | inferred from electronic annotation with InterPro:IPR012724 neurogenesis ; GO:0022008 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001531327 "anon-WO0118547.404, CG8863, Droj2, DROJ2, DnaJL2A, DnaJ-like-2" "IPR001305:Heat shock protein DnaJ, cysteine-rich domain, IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site, IPR012724:Chaperone DnaJ" CG8863 11-Aug-17 DroID_v2017_08 "Drer\dnaja2l, Drer\dnaja1, Drer\dnajc16, Drer\dnaja, Drer\dnaja2, Drer\dnajc16l" "Scer\SIS1, Scer\XDJ1, Scer\YDJ1, Scer\SCJ1, Scer\APJ1" "Cele\dnj-3, Cele\dnj-19, Cele\dnj-14, Cele\dnj-8, Cele\dnj-12" "Xtro\dnaja1, Xtro\dnaja4.2, Xtro\dnaja4.1, Xtro\dnaja2" "Mmus\Dnajc16, Mmus\Dnaja4, Mmus\Dnaja1, Mmus\Dnaja2" "Hsap\DNAJA2, Hsap\DNAJA1, Hsap\DNAJA4, Hsap\DNAJC16" "lethal,neuroanatomy defective" ganglion mother cell DRSC16450 I 1.533035775 2.653205633 -1.252964288 0.49932945 -1.285512664 -0.083718323 FBgn0037417 Osi10 Osiris 10 http://flybase.org/reports/FBgn0037417 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi10, CG15593" IPR012464:Protein of unknown function DUF1676 CG15593 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC12279 I 1.427297196 1.537261355 0.567794344 0.155738551 0.54609664 -0.093914367 FBgn0284220 Top2 Topoisomerase 2 http://flybase.org/reports/FBgn0284220 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001154, InterPro:IPR001241, InterPro:IPR002205, InterPro:IPR013506, InterPro:IPR013757, InterPro:IPR013758, InterPro:IPR013759, InterPro:IPR013760, InterPro:IPR018522 DNA binding ; GO:0003677 | inferred from direct assay DNA topoisomerase type II (ATP-hydrolyzing) activity ; GO:0003918 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from direct assay satellite DNA binding ; GO:0003696 | inferred from direct assay rDNA binding ; GO:0000182 | inferred from direct assay four-way junction DNA binding ; GO:0000400 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with barr inferred from physical interaction with ph-p" chromosome condensation ; GO:0030261 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | traceable author statement mitotic nuclear division ; GO:0007067 | traceable author statement chromatin silencing ; GO:0006342 | inferred from direct assay DNA topological change ; GO:0006265 | inferred from direct assay metaphase plate congression ; GO:0051310 | inferred from direct assay sister chromatid segregation ; GO:0000819 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype CHRAC ; GO:0008623 | inferred from direct assay CHRAC ; GO:0008623 | NOT inferred from direct assay ACF complex ; GO:0016590 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay condensed chromosome ; GO:0000793 | colocalizes_with inferred from direct assay "suo, Top2, CG10223, TopoII, TOP2, topoII, topo II, dTopoII, CHRAC, TOPOII, top2, dCHRAC, Topo II, TopII, TOPO II" "IPR034157:DNA topoisomerase 2, TOPRIM domain, IPR031660:C-terminal associated domain of TOPRIM, IPR018522:DNA topoisomerase, type IIA, conserved site, IPR006171:TOPRIM domain, IPR001154:DNA topoisomerase II, eukaryotic-type, IPR001241:DNA topoisomerase, type IIA, IPR002205:DNA topoisomerase, type IIA, subunit A/C-terminal, IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR013506:DNA topoisomerase, type IIA, subunit B, domain 2, IPR013758:DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta, IPR013759:DNA topoisomerase, type IIA, central domain, IPR013760:DNA topoisomerase, type IIA-like domain, IPR013757:Type IIA DNA topoisomerase subunit A, alpha-helical domain, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR024946:Arginine repressor C-terminal-like domain, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup" CG10223 11-Aug-17 DroID_v2017_08 "Drer\top2b, Drer\top2a" Scer\TOP2 "Cele\cin-4, Cele\R05D3.12, Cele\top-2" "Xtro\top2b, Xtro\top2a" "Mmus\Top2b, Mmus\Top2a" "Hsap\TOP2B, Hsap\TOP2A" "neuroanatomy defective,somatic clone,lethal,recessive,partially lethal - majority die,male fertile,female sterile,heat sensitive,male sterile,viable,lethal - all die before end of first instar larval stage,lethal - all die before end of second instar larval stage,small body,developmental rate defective,lethal - all die during first instar larval stage,visible" "adult mushroom body,somatic clone,imaginal disc,heat sensitive,embryonic/larval brain,polytene chromosomeExel9043),ovary,female germline stem cell,embryonic/larval salivary gland,embryonic/larval central nervous system,mesothoracic tergum" DRSC03459 I 0.589767748 1.986121485 -0.956562385 -0.369826165 -1.008581182 -0.061813505 FBgn0039636 Atg14 Autophagy-related 14 http://flybase.org/reports/FBgn0039636 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of autophagy ; GO:0010508 | inferred from electronic annotation with InterPro:IPR018791 regulation of autophagy ; GO:0010506 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype "phosphatidylinositol 3-kinase complex, class III, type I ; GO:0034271 | inferred from sequence or structural similarity with SGD:S000000332" "Atg14, CG11877" IPR018791:UV radiation resistance protein/autophagy-related protein 14 CG11877 11-Aug-17 DroID_v2017_08 "Drer\tbpl2, Drer\zgc:113944" - Cele\epg-8 Xtro\atg14 Mmus\Atg14 Hsap\ATG14 "viable,fertile" "embryonic/larval fat body,somatic clone | third instar larval stage" FBgn0033412 CG13955 - http://flybase.org/reports/FBgn0033412 protein_coding_gene - - - CG13955 - CG13955 11-Aug-17 DroID_v2017_08 Drer\tchp - - - Mmus\Mad1l1 - viable FBgn0263018 snRNA:U4atac:82E small nuclear RNA U4atac at 82E http://flybase.org/reports/FBgn0263018 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U4atac snRNP ; GO:0005690 | inferred from sequence or structural similarity "CR43269, U4atac, U4atac-82E, CR32860, snRNA:U4atac:82E, U4atac:cno-a, snRNA_01, chr3R:1020715..1020926" - CR43269 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065379 l(2)SH1671 lethal (2) SH1671 http://flybase.org/reports/FBgn0065379 gene - - - "l(2)SH1671, l(2)SH2 1671" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040396 CG3939 - http://flybase.org/reports/FBgn0040396 protein_coding_gene protein-disulfide reductase activity ; GO:0047134 | inferred from biological aspect of ancestor with PANTHER:PTN000278790 - cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000278790 "EG:140G11.5, BEST:SD07039, CG3939" "IPR010357:Protein of unknown function DUF953, thioredoxin-like, IPR012336:Thioredoxin-like fold" CG3939 11-Aug-17 DroID_v2017_08 Drer\txndc17 - Cele\Y71H2AR.1 - Mmus\Txndc17 Hsap\TXNDC17 viable FBgn0034400 CG15099 - http://flybase.org/reports/FBgn0034400 protein_coding_gene - Golgi to endosome transport ; GO:0006895 | inferred from biological aspect of ancestor with PANTHER:PTN000361806 trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000361806 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000361806 CG15099 "IPR007249:Dopey, N-terminal" CG15099 11-Aug-17 DroID_v2017_08 "Drer\dopey1, Drer\dopey2" Scer\DOP1 Cele\pad-1 Xtro\dopey2 "Mmus\Dopey2, Mmus\Dopey1" "Hsap\DOPEY2, Hsap\DOPEY1" viable DRSC06528 K 0.637701493 0.163588789 1.422511617 0.004959979 -2.167634915 -0.421374931 FBgn0265912 CR44701 - http://flybase.org/reports/FBgn0265912 non_protein_coding_gene - - - "lincRNA.97, CR44701" - CR44701 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065711 l(2)SH0591 lethal (2) SH0591 http://flybase.org/reports/FBgn0065711 gene - - - "l(2)SH0591, l(2)SH2 0591" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085751 CR40582 - http://flybase.org/reports/FBgn0085751 rRNA_gene - - - CR40582 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058389 CG40389 - http://flybase.org/reports/FBgn0058389 protein_coding_gene - - - CG40389 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267921 CR46202 - http://flybase.org/reports/FBgn0267921 non_protein_coding_gene - - - "CR46202, lincRNA.227" - CR46202 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045759 bin biniou http://flybase.org/reports/FBgn0045759 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from genetic interaction with dpp sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from genetic interaction with Hand transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from genetic interaction with βTub60D" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype mesodermal cell fate commitment ; GO:0001710 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Bin, Dmbin, FoxF, CG18647, XIV, l(3)65CEe, bin, FOXF, DmFoxF, binI, BIN" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG18647 11-Aug-17 DroID_v2017_08 "Drer\foxf1, Drer\foxf2b, Drer\foxq2, Drer\foxa3, Drer\foxf2a, Drer\foxq1a, Drer\foxp4, Drer\foxh1, Drer\foxi3b" "Scer\HCM1, Scer\FKH2, Scer\FHL1, Scer\FKH1" "Cele\fkh-9, Cele\let-381" "Xtro\foxq1, Xtro\foxf2, Xtro\foxd3, Xtro\foxh1, Xtro\foxp4, Xtro\foxf1, Xtro\foxd4l1.1" "Mmus\Foxp4, Mmus\Foxf2, Mmus\Foxi2, Mmus\Foxk1, Mmus\Foxk2, Mmus\Foxf1, Mmus\Foxh1, Mmus\Foxq1, Mmus\Foxs1" "Hsap\FOXN1, Hsap\FOXF1, Hsap\FOXQ1, Hsap\FOXC2, Hsap\FOXD4L1, Hsap\FOXD4L3, Hsap\FOXI2, Hsap\FOXK1, Hsap\FOXP4, Hsap\FOXH1, Hsap\FOXF2" "lethal,cell migration defective,viable" "anterior embryonic/larval midgut,presumptive embryonic salivary gland,circular visceral muscle primordium,midgut constriction,longitudinal visceral muscle primordium,visceral mesoderm derivative,embryonic somatic muscle,embryonic pericardial cell" FBgn0267925 CR46206 - http://flybase.org/reports/FBgn0267925 non_protein_coding_gene - - - "CR46206, lincRNA.123" - CR46206 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023112 anon-10Av anon-10Av http://flybase.org/reports/FBgn0023112 - gene - - - "15, anon-10Av" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034565 CG15650 - http://flybase.org/reports/FBgn0034565 protein_coding_gene - - - CG15650 - CG15650 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0023409 Ars-region46 Autonomous replicating sequence region 46 http://flybase.org/reports/FBgn0023409 - region - - - "dARS46, Ars-region46, Ars46" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029942 CG2059 - http://flybase.org/reports/FBgn0029942 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2059 "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG2059 11-Aug-17 DroID_v2017_08 "Drer\abhd11, Drer\abhd8b" "Scer\LPX1, Scer\YGR015C, Scer\IMO32" "Cele\abhd-11.1, Cele\abhd-11.2" "Xtro\abhd8, Xtro\abhd11" "Mmus\Abhd8, Mmus\Abhd11" Hsap\ABHD11 FBgn0000238 buo burnt orange http://flybase.org/reports/FBgn0000238 - gene - - - buo - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" pigment cell FBgn0266152 CR44858 - http://flybase.org/reports/FBgn0266152 non_protein_coding_gene - - - CR44858 - CR44858 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267088 CR45532 - http://flybase.org/reports/FBgn0267088 non_protein_coding_gene - - - CR45532 - CR45532 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003373 Sgs3 Salivary gland secretion 3 http://flybase.org/reports/FBgn0003373 - protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model cellular response to ecdysone ; GO:0071390 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from sequence model "Sgs3, sgs3, Sgs-3, sgs-3, Sgs, SGS378, DMSGS378, SGS-3, 68C GII, CG11720, Muc68Cb, Glue" - CG11720 11-Aug-17 DroID_v2017_08 - Scer\SED1 Cele\Y43F8C.16 - - - larval stage | third instar embryonic/larval salivary gland

larval stage | late third instar larval stage embryonic/larval salivary gland

electrophoretic variant FBgn0002661 mat(2)cell-J maternal effect cellularisation defect J http://flybase.org/reports/FBgn0002661 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)cellRE43, mat(2)cell-J" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0037625 CG11768 - http://flybase.org/reports/FBgn0037625 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11768 - CG11768 11-Aug-17 DroID_v2017_08 - Scer\YPR148C Cele\sup-36 - - Hsap\ACTC1 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0035257 CG12011 - http://flybase.org/reports/FBgn0035257 protein_coding_gene - - - "clone 1.72, anon-EST:Liang-1.72, CG12011" - CG12011 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08219 K -0.32963451 -0.354516878 -0.780871222 -0.318181204 1.533812185 -0.083838661 FBgn0051859 CG31859 - http://flybase.org/reports/FBgn0051859 protein_coding_gene - - - CG31859 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028984 Spn88Ea Serpin 88Ea http://flybase.org/reports/FBgn0028984 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 extracellular region ; GO:0005576 | inferred from direct assay "CG18525, sp5, Sp5, spn5, Spn88Ea, Spn5" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG18525 11-Aug-17 DroID_v2017_08 "Drer\serpind1, Drer\serpinb1l3, Drer\serpinf2b, Drer\serping1, Drer\agt, Drer\serpini1, Drer\serpinb1l2, Drer\serpinf1, Drer\zgc:173729, Drer\serpinf2a, Drer\serpinb1" - "Cele\srp-8, Cele\srp-7, Cele\srp-1, Cele\srp-2, Cele\srp-3, Cele\srp-6, Cele\C28G1.2" - "Mmus\Serpinb6b, Mmus\Serpinb3a, Mmus\Serpinb3c, Mmus\Serpinb3b, Mmus\Serpinb1a, Mmus\Serpinf1, Mmus\Serpinb6a, Mmus\Serpini2, Mmus\Serpind1, Mmus\Serpinb7, Mmus\Serpinb1b, Mmus\Serpinb3d, Mmus\Serpinb11, Mmus\Serpinf2, Mmus\Serpinb1c, Mmus\Serpini1, Mmus\Serpinb9c, Mmus\Agt" "Hsap\SERPINB1, Hsap\SERPINF2, Hsap\SERPINI2, Hsap\SERPINB3, Hsap\SERPINB6, Hsap\SERPINB7, Hsap\SERPINB4, Hsap\AGT, Hsap\SERPINF1, Hsap\SERPINI1, Hsap\SERPIND1" "short lived,viable" wing FBgn0065741 l(2)SH0526 lethal (2) SH0526 http://flybase.org/reports/FBgn0065741 gene - - - "l(2)SH0526, l(2)SH2 0526" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040081 p88 p88 http://flybase.org/reports/FBgn0040081 gene - - - p88 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038051 CG17207 - http://flybase.org/reports/FBgn0038051 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002995 cellular_component ; GO:0005575 | no biological data available "BcDNA:AT11646, CG17207" IPR002995:Surfeit locus 4 CG17207 11-Aug-17 DroID_v2017_08 "Drer\surf4l, Drer\surf4" Scer\ERV29 "Cele\sft-4, Cele\T02E1.7" "Xtro\surf4.2, Xtro\surf4.1" Mmus\Surf4 Hsap\SURF4 FBgn0035272 mRpL46 mitochondrial ribosomal protein L46 http://flybase.org/reports/FBgn0035272 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9H2W6 structural constituent of ribosome ; GO:0003735 | traceable author statement" mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9H2W6 "MRP-L46, CG13922, mRpL46, MRpL46" "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like, IPR021757:Ribosomal protein L46, IPR033650:Mitochondrial ribosomal protein L46 NUDIX" CG13922 11-Aug-17 DroID_v2017_08 Drer\mrpl46 Scer\MRPL17 Cele\mrpl-46 Xtro\mrpl46 Mmus\Mrpl46 Hsap\MRPL46 "viable,visible" trichogen cell DRSC08391 I -1.674590583 -1.322617881 -0.691824449 -1.236825347 0.810337925 -0.452405536 FBgn0036081 CG6559 - http://flybase.org/reports/FBgn0036081 protein_coding_gene - - - CG6559 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085691 CG41560 - http://flybase.org/reports/FBgn0085691 protein_coding_gene - - - CG41560 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020818 l(3)98Dl lethal (3) 98Dl http://flybase.org/reports/FBgn0020818 - gene - - - l(3)98Dl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038365 CG9593 - http://flybase.org/reports/FBgn0038365 protein_coding_gene transmembrane receptor protein tyrosine kinase activator activity ; GO:0030297 | inferred from sequence or structural similarity with HGNC:487 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with HGNC:487 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:487 "CG9593, AAF55227, FBpp0082632" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG9593 11-Aug-17 DroID_v2017_08 "Drer\si:zfos-2330d3.6, Drer\fgg, Drer\tnw, Drer\angptl6, Drer\angpt1, Drer\si:ch211-157b11.8, Drer\zgc:194887, Drer\LOC555374, Drer\wu:fj11g02, Drer\tnr, Drer\angpt2b, Drer\angpt2a, Drer\angptl3, Drer\zmp:0000000846, Drer\si:dkeyp-51b7.3, Drer\si:ch1073-110a20.2, Drer\fgl2b, Drer\tnxba, Drer\zgc:171687, Drer\angpt4, Drer\zgc:173915, Drer\tnc, Drer\LOC100334800, Drer\si:ch1073-110a20.3, Drer\LOC100007488, Drer\angptl5, Drer\mfap4, Drer\si:zfos-2330d3.1, Drer\si:zfos-2330d3.8, Drer\fndc7a, Drer\fgl1, Drer\si:ch1073-110a20.1, Drer\angptl2a, Drer\si:ch211-287a12.9, Drer\angptl1a, Drer\angptl4, Drer\angptl7, Drer\si:zfos-2330d3.3, Drer\angptl2b, Drer\fgl2a, Drer\fga, Drer\fgb, Drer\fibcd1" - "Cele\ensh-1, Cele\T15B7.1" "Xtro\fcn2, Xtro\tnc, Xtro\tnn, Xtro\LOC100488177, Xtro\angptl3, Xtro\fgb, Xtro\angptl2, Xtro\fgg, Xtro\tnr, Xtro\fcn1, Xtro\tnxb, Xtro\angptl4, Xtro\fgl1, Xtro\fgl2, Xtro\fga, Xtro\angptl5, Xtro\LOC100491105, Xtro\angpt4, Xtro\mfap4, Xtro\angpt1, Xtro\fibcd1, Xtro\LOC100497330, Xtro\fcn3" "Mmus\Mfap4, Mmus\Fgg, Mmus\Angptl1, Mmus\Fga, Mmus\Fgb, Mmus\Angptl2, Mmus\Tnn, Mmus\Fgl2, Mmus\Fgl1, Mmus\Tnr, Mmus\Tnc, Mmus\Fcna, Mmus\Angptl7, Mmus\Angptl4, Mmus\Angptl3, Mmus\Fcnb, Mmus\Angptl6, Mmus\Fibcd1, Mmus\Tnxb, Mmus\Angpt1, Mmus\Fndc7, Mmus\Angpt2, Mmus\Angpt4" "Hsap\FGA, Hsap\ANGPT4, Hsap\FCN1, Hsap\ANGPT2, Hsap\ANGPT1, Hsap\ANGPTL4, Hsap\FCN3, Hsap\FNDC7, Hsap\TNC, Hsap\FGB, Hsap\ANGPTL7, Hsap\FGL1, Hsap\FGG, Hsap\ANGPTL6, Hsap\ANGPTL1, Hsap\MFAP4, Hsap\FCN2, Hsap\ANGPTL3, Hsap\ANGPTL2, Hsap\FGL2, Hsap\ANGPTL5, Hsap\TNR, Hsap\TNN, Hsap\TNXB, Hsap\FIBCD1" viable FBgn0000500 Dsk Drosulfakinin http://flybase.org/reports/FBgn0000500 "FBan0018090, FBgn0037214, FBgn0062936" protein_coding_gene neuropeptide hormone activity ; GO:0005184 | non-traceable author statement neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with CCKLR-17D1 neuropeptide hormone activity ; GO:0005184 | inferred from direct assay neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from direct assay inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay adult feeding behavior ; GO:0008343 | inferred from mutant phenotype positive regulation of cytosolic calcium ion concentration ; GO:0007204 | inferred from direct assay regulation of smooth muscle contraction ; GO:0006940 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement multicellular organismal response to stress ; GO:0033555 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred by curator from GO:0005184 "DSK, Drm-SK-2, Drm-SK-1, dsk, Drm-SK-0, DSK-I, CCK, DrmSK-II, DrmSK-I, CG18090, BcDNA:RH46857, Dsk, Drm-SK, SK-0, DSK I, DSK II, DSK-0, DSK-1, DSK-2, Drosulfakinin 1, Drosulfakinin 2" "IPR013152:Gastrin/cholecystokinin, conserved site" CG18090 11-Aug-17 DroID_v2017_08 - - - - - - adult stage protocerebrum

"neuroanatomy defective,neurophysiology defective,stress response defective,locomotor behavior defective,viable,fertile" "embryonic/larval neuromuscular junction,NMJ bouton,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage" DRSC12347 K 1.205861528 -0.374293819 0.180803248 0.378568853 2.394881714 1.053449708 FBgn0264360 CR43812 - http://flybase.org/reports/FBgn0264360 non_protein_coding_gene - - - CR43812 - CR43812 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040055 CG14474 - http://flybase.org/reports/FBgn0040055 protein_coding_gene - - - CG14474 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029507 Tsp42Ed Tetraspanin 42Ed http://flybase.org/reports/FBgn0029507 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG12846, Dm.Tsp42Ed, GH07074, BcDNA:GH07074, Tsp42Ed, Tsp42E" "IPR018499:Tetraspanin/Peripherin, IPR018503:Tetraspanin, conserved site, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12846 11-Aug-17 DroID_v2017_08 Drer\cd63 - "Cele\tsp-13, Cele\tsp-14, Cele\tsp-7, Cele\tsp-3, Cele\tsp-1, Cele\tsp-2" Xtro\cd63 Mmus\Cd63 Hsap\CD63 FBgn0032110 CG3748 - http://flybase.org/reports/FBgn0032110 protein_coding_gene - - - "BcDNA:AT30262, anon-WO0140519.143, CG3748" "IPR003887:LEM domain, IPR011015:LEM/LEM-like domain" CG3748 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038468 CG5225 - http://flybase.org/reports/FBgn0038468 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5225 IPR008160:Collagen triple helix repeat CG5225 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-44a8.4, Drer\c1qtnf7, Drer\col15a1b, Drer\c1qtnf2" - - - "Mmus\C1qtnf7, Mmus\C1qtnf2, Mmus\Col18a1" "Hsap\C1QTNF2, Hsap\C1QTNF7, Hsap\COL18A1" "viable,fertile" FBgn0085440 Lgr4 Leucine-rich repeat-containing G protein-coupled receptor 4 http://flybase.org/reports/FBgn0085440 protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR008112 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model protein-hormone receptor activity ; GO:0016500 | inferred from sequence or structural similarity" G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model" "Lgr4, CG32637, anon-WO0170980.20, anon-WO0170980.19, CG4187, CG34411, DLGR4, dLGR4, lgr4" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001611:Leucine-rich repeat, IPR008112:Relaxin receptor, IPR017452:GPCR, rhodopsin-like, 7TM, IPR025875:Leucine rich repeat 4, IPR034298:TSH/LHCG/FSH receptor, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR003591:Leucine-rich repeat, typical subtype" CG34411 11-Aug-17 DroID_v2017_08 "Drer\fshr, Drer\lhcgr, Drer\tshr, Drer\rxfp1, Drer\lgr4, Drer\rxfp2b, Drer\rxfp2a, Drer\rxfp2l" - "Cele\fshr-1, Cele\sma-10" "Xtro\rxfp2, Xtro\fshr, Xtro\tshr, Xtro\rxfp1" "Mmus\Rxfp2, Mmus\Flrt2, Mmus\Lgr4, Mmus\Lhcgr, Mmus\Lgr5, Mmus\Lrfn5, Mmus\Tshr, Mmus\Rxfp1, Mmus\Fshr, Mmus\Lgr6" "Hsap\LHCGR, Hsap\LGR5, Hsap\FLRT2, Hsap\RXFP1, Hsap\LGR4, Hsap\LGR6, Hsap\TSHR, Hsap\RXFP2, Hsap\LRFN5, Hsap\FSHR" FBgn0010191 tu-So tu-So http://flybase.org/reports/FBgn0010191 - gene - - - "tu-So[c], tu-So" - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0041102 ocn ocnus http://flybase.org/reports/FBgn0041102 protein_coding_gene phosphohistidine phosphatase activity ; GO:0008969 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 peptidyl-histidine dephosphorylation ; GO:0035971 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 "CG7929, bs29e10.y1, BcDNA:GH02250, ocn, Ocn" IPR007702:Janus CG7929 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-51e6.1, Drer\phpt1" - Cele\phip-1 Xtro\phpt1 Mmus\Phpt1 Hsap\PHPT1 viable FBgn0001383 l(1)2Bo lethal (1) 2Bo http://flybase.org/reports/FBgn0001383 - gene - - - l(1)2Bo - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037898 CG18643 - http://flybase.org/reports/FBgn0037898 protein_coding_gene aminoacyl-tRNA editing activity ; GO:0002161 | inferred from biological aspect of ancestor with PANTHER:PTN000049487 D-tyrosyl-tRNA(Tyr) deacylase activity ; GO:0051500 | inferred from biological aspect of ancestor with PANTHER:PTN000049487 tRNA metabolic process ; GO:0006399 | inferred from biological aspect of ancestor with PANTHER:PTN000049487 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000049487 CG18643 "IPR023509:D-Tyr tRNAtyr deacylase-like domain, IPR003732:D-aminoacyl-tRNA deacylase DTD" CG18643 11-Aug-17 DroID_v2017_08 "Drer\dtd2, Drer\dtd1, Drer\gcc1" Scer\DTD1 Cele\pqn-68 "Xtro\dtd2, Xtro\gcc1, Xtro\dtd1" "Mmus\Gcc1, Mmus\Dtd1, Mmus\Dtd2" "Hsap\DTD1, Hsap\GCC1, Hsap\DTD2" DRSC15362 K -0.244006956 0.259801922 0.215989131 0.328945131 0.227800281 1.566617609 FBgn0024342 KH2-9 KH domain cDNA KH2-9 http://flybase.org/reports/FBgn0024342 - gene - - - KH2-9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035888 CG7120 - http://flybase.org/reports/FBgn0035888 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "BcDNA:AT15424, CG7120, gi7295100" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG7120 11-Aug-17 DroID_v2017_08 - - "Cele\F32G8.2, Cele\T07G12.3, Cele\Y73F8A.35, Cele\T23E1.1, Cele\Y41E3.1, Cele\R03G8.1, Cele\F32D8.2, Cele\Y38A10A.2, Cele\M03F8.5, Cele\F15H10.7, Cele\F10C2.3, Cele\F07C3.3, Cele\R03G8.3, Cele\K03A11.4" - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0024883 l(2)04548 lethal (2) 04548 http://flybase.org/reports/FBgn0024883 - gene - - - l(2)04548 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013618 l(3)L5150 lethal (3) L5150 http://flybase.org/reports/FBgn0013618 - gene - - - l(3)L5150 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037427 Osi17 Osiris 17 http://flybase.org/reports/FBgn0037427 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG15598, Osi17, mdcds_43703" IPR012464:Protein of unknown function DUF1676 CG15598 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0003707 TipB Temperature-induced paralytic B http://flybase.org/reports/FBgn0003707 - gene - - - TipB - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,paralytic,heat sensitive" FBgn0020523 nerd nerd http://flybase.org/reports/FBgn0020523 - gene molecular_function ; GO:0003674 | no biological data available mating behavior ; GO:0007617 | inferred from mutant phenotype pheromone biosynthetic process ; GO:0042811 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Nerd, nerd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mating defective,male,recessive" FBgn0013582 l(3)82Fj lethal (3) 82Fj http://flybase.org/reports/FBgn0013582 - gene - - - l(3)82Fj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041337 Cyp309a2 Cyp309a2 http://flybase.org/reports/FBgn0041337 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "309a2, CG18559, Cyp309a2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG18559 11-Aug-17 DroID_v2017_08 "Drer\cyp3c3, Drer\tbxas1, Drer\cyp3c1, Drer\cyp3c4, Drer\cyp3c2, Drer\cyp3a65" "Scer\DIT2, Scer\ERG11" "Cele\cyp-13A11, Cele\cyp-13A10, Cele\cyp-13A12, Cele\cyp-25A1, Cele\cyp-13A4, Cele\cyp-13A8, Cele\cyp-13A3, Cele\cyp-13A2, Cele\cyp-13A1, Cele\cyp-44A1, Cele\cyp-13A6, Cele\cyp-25A2, Cele\cyp-25A3, Cele\cyp-43A1, Cele\cyp-13A7, Cele\cyp-13A5, Cele\cyp-25A4, Cele\cyp-13B1, Cele\cyp-13B2, Cele\cyp-25A6" "Xtro\tbxas1, Xtro\cyp3a5, Xtro\LOC100494419, Xtro\cyp3a4" "Mmus\Cyp3a59, Mmus\Cyp3a16, Mmus\Cyp3a41a, Mmus\Tbxas1, Mmus\Cyp3a25, Mmus\Cyp3a57, Mmus\Cyp3a41b, Mmus\Cyp3a11, Mmus\Cyp3a13, Mmus\Cyp3a44" "Hsap\CYP3A4, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\CYP3A43, Hsap\TBXAS1, Hsap\CYP3A7-CYP3A51P" viable FBgn0024643 l(2)k11326 lethal (2) k11326 http://flybase.org/reports/FBgn0024643 - gene - - - "113/26, l(2)k11326" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0002562 Lsp1alpha Larval serum protein 1 alpha http://flybase.org/reports/FBgn0002562 - protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay larval serum protein complex ; GO:0005616 | inferred from direct assay "Lsp1, Lsp1-alpha, LSP-1, Lsp1alpha, CG2559, DmeLSP1a, LSP-1alpha, LSP 1, Lsp-1alpha, LSP1alpha, LSP1-alpha, LSP-1 alpha, LSP1, LSP1ALPHA" "IPR000896:Hemocyanin/hexamerin middle domain, IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR008922:Uncharacterised domain, di-copper centre, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set" CG2559 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | second instar -- larval stage | third instar , larval stage | third instar " embryonic/larval fat body

"electrophoretic variant,viable,fertile" egg DRSC25329 K 0.252334637 -0.125277535 -0.230797314 0.298288006 0.166907384 -2.559554076 FBgn0039027 CG7031 - http://flybase.org/reports/FBgn0039027 protein_coding_gene - - - CG7031 IPR011989:Armadillo-like helical CG7031 11-Aug-17 DroID_v2017_08 - - Cele\T26C11.2 - Mmus\Ggn "Hsap\GGN, Hsap\TPRX1" viable DRSC23028 K 1.844139299 1.48416253 FBgn0030936 CG6481 - http://flybase.org/reports/FBgn0030936 protein_coding_gene - - - CG6481 - CG6481 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040368 eIF4E7 eukaryotic translation initiation factor 4E7 http://flybase.org/reports/FBgn0040368 protein_coding_gene RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from genetic interaction with SGD:S000005499 RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity eukaryotic initiation factor 4G binding ; GO:0031370 | inferred from physical interaction with eIF4G1 protein binding ; GO:0005515 | inferred from physical interaction with Thor translational initiation ; GO:0006413 | inferred from genetic interaction with SGD:S000005499 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from physical interaction with eIF4G1 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity "CG32859, EG:BACR42I17.1, CT31794, CG11393, CG11392, eIF4E, eIF4E7, eIF4E-7" "IPR001040:Translation Initiation factor eIF- 4e, IPR023398:Translation Initiation factor eIF- 4e-like, IPR019770:Eukaryotic translation initiation factor 4E (eIF-4E), conserved site" CG32859 11-Aug-17 DroID_v2017_08 "Drer\eif4eb, Drer\eif4ea, Drer\eif4e1b, Drer\sesn2, Drer\si:zfos-80g12.1, Drer\sesn1, Drer\eif4e1c" Scer\CDC33 "Cele\ife-5, Cele\ife-1, Cele\ife-3, Cele\ife-2" "Xtro\sesn1, Xtro\sesn3, Xtro\eif4e, Xtro\eif4e1b" "Mmus\Sesn2, Mmus\Sesn1, Mmus\Eif4e, Mmus\Sesn3, Mmus\Eif4e1b" "Hsap\SESN2, Hsap\SESN3, Hsap\SESN1, Hsap\EIF4E, Hsap\EIF4E1B" "viable,partially lethal - majority die,some die during pupal stage" FBgn0263770 CR43687 - http://flybase.org/reports/FBgn0263770 pseudogene_attribute - - - CR43687 - CR43687 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065445 l(2)SH1426 lethal (2) SH1426 http://flybase.org/reports/FBgn0065445 gene - - - "l(2)SH1426, l(2)SH2 1426" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014927 anon-72ABk anon-72ABk http://flybase.org/reports/FBgn0014927 - gene - - - anon-72ABk - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266052 CR44817 - http://flybase.org/reports/FBgn0266052 non_protein_coding_gene - - - CR44817 - CR44817 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014881 Ssb-c15a Single stranded-binding protein c15a http://flybase.org/reports/FBgn0014881 - gene - - - "c15a, Ssb-c15a" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265911 CR44700 - http://flybase.org/reports/FBgn0265911 non_protein_coding_gene - - - CR44700 - CR44700 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070039 3R-64-22 3R-64-22 http://flybase.org/reports/FBgn0070039 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-64-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" FBgn0265308 CR44281 - http://flybase.org/reports/FBgn0265308 non_protein_coding_gene - - - CR44281 - CR44281 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264899 CG44090 - http://flybase.org/reports/FBgn0264899 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44090 - CG44090 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037202 Ssl1 Suppressor of stem-loop mutation http://flybase.org/reports/FBgn0037202 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004595 transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675 nucleic acid binding ; GO:0003676 | inferred from biological aspect of ancestor with PANTHER:PTN000294370" transcriptional open complex formation at RNA polymerase II promoter ; GO:0001113 | inferred from sequence or structural similarity with HGNC:4656 nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity with HGNC:4656 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4656 inferred from sequence or structural similarity with SGD:S000003995 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000294370 nucleotide-excision repair ; GO:0006289 | inferred from biological aspect of ancestor with PANTHER:PTN000294370 promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from sequence or structural similarity with HGNC:4656 holo TFIIH complex ; GO:0005675 | inferred from direct assay core TFIIH complex ; GO:0000439 | inferred from sequence or structural similarity with HGNC:4656 inferred from sequence or structural similarity with SGD:S000003995 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:4656 holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:4656 inferred from sequence or structural similarity with SGD:S000003995 "SSL1, CG11115, Ssl1, p44, ssl1" "IPR002035:von Willebrand factor, type A, IPR004595:TFIIH C1-like domain, IPR012170:TFIIH subunit Ssl1/p44, IPR013087:Zinc finger C2H2-type, IPR007198:Ssl1-like" CG11115 11-Aug-17 DroID_v2017_08 Drer\gtf2h2 Scer\SSL1 Cele\T16H12.4 Xtro\gtf2h2 Mmus\Gtf2h2 "Hsap\GTF2H2C_2, Hsap\GTF2H2C, Hsap\GTF2H2" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262290 mir-iab-8 mir-iab-8 stem loop http://flybase.org/reports/FBgn0262290 miRNA_gene - - - "miR-iab-8, mir-iab-4as-5p, miR-iab-4as, dme-mir-iab-8, iab-8, miR-iab-4AS, mir-iab-4as, mir-iab-8, mir-iab8, miR-iab-8-5p, CR42997, MIR-iab-4as, iab-8 miRNA, dme-iab-8, dme-miR-iab-8, MiR-iab8, miR-iab8-3p, miR-iab8-5p" - CR42997 11-Aug-17 DroID_v2017_08 - - - - - - "visible,homeotic,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "wing,ectopic,haltere" FBgn0000814 fs(1)K254 female sterile (1) K254 http://flybase.org/reports/FBgn0000814 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available fs(1)K254 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile soma-dependent,female sterile,recessive,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" "dorsal appendage,chorion" FBgn0053766 CG33766 - http://flybase.org/reports/FBgn0053766 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14458, CG33766" IPR010512:Protein of unknown function DUF1091 CG33766 11-Aug-17 DroID_v2017_08 - - - - - - DRSC11717 E 0.911471654 -0.036711042 2.562516219 0.920692551 -0.005139367 0.971594994 FBgn0267641 CR45979 - http://flybase.org/reports/FBgn0267641 non_protein_coding_gene - - - CR45979 - CR45979 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260494 boa baobab http://flybase.org/reports/FBgn0260494 gene - axonogenesis ; GO:0007409 | inferred from mutant phenotype - boa - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,axon" FBgn0004072 fs(2)mel6 female sterile (2) maternal effect lethal 6 http://flybase.org/reports/FBgn0004072 - gene - - - "Mel 6, fs(2)mel6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,semidominant,some die during embryonic stage" "cephalopharyngeal skeleton,maternal effect,embryonic head" FBgn0052269 CG32269 - http://flybase.org/reports/FBgn0052269 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP124, CG33161, CG11530, CG32269" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG32269 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.7, Drer\si:dkey-78l4.10" - "Cele\svh-1, Cele\try-1" - "Mmus\Prss53, Mmus\Prss36, Mmus\Prss55" "Hsap\PRSS57, Hsap\PRSS36, Hsap\PRSS53" FBgn0044382 T:SS-ea Signal sequence of ea http://flybase.org/reports/FBgn0044382 engineered_tag - - - "T:SS-ea, T:ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052734 CG32734 - http://flybase.org/reports/FBgn0052734 protein_coding_gene - - - CG32734 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003863 alphaTry alphaTrypsin http://flybase.org/reports/FBgn0003863 FBgn0033621 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP102, Try, DmAlphaTry, alpha, alphaTry, CG18444" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG18444 11-Aug-17 DroID_v2017_08 "Drer\zgc:55888, Drer\prss60.2, Drer\ctrl, Drer\prss60.3, Drer\zgc:163079, Drer\zgc:123295, Drer\zgc:112038, Drer\tmprss4b, Drer\try, Drer\zgc:92590, Drer\zgc:153968, Drer\zgc:112160, Drer\LOC562139, Drer\prss60.1, Drer\si:dkeyp-93a5.2, Drer\si:ch211-165b19.9" - Cele\try-1 - "Mmus\Prss55, Mmus\Try4, Mmus\Prss1, Mmus\2210010C04Rik, Mmus\Gm5771, Mmus\Prss2, Mmus\Klk1b3, Mmus\Prss3, Mmus\Prss53, Mmus\Prss34, Mmus\Klk14, Mmus\Gm10334, Mmus\Habp2, Mmus\Prss36, Mmus\Try10" "Hsap\TPSG1, Hsap\PRSS45, Hsap\PRSS36, Hsap\PRSS3, Hsap\PRSS38, Hsap\PRSS53, Hsap\KLK2, Hsap\PRSS33, Hsap\PRSS48, Hsap\CMA1, Hsap\KLK1, Hsap\PRSS27, Hsap\PRSS1, Hsap\PRSS22, Hsap\PRSS8" " larval stage | third instar , adult stage " larval digestive system | restricted

FBgn0036266 CG5626 - http://flybase.org/reports/FBgn0036266 protein_coding_gene tRNA-intron endonuclease activity ; GO:0000213 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001077630 tRNA-type intron splice site recognition and cleavage ; GO:0000379 | inferred from biological aspect of ancestor with PANTHER:PTN001077630 tRNA-intron endonuclease complex ; GO:0000214 | inferred from biological aspect of ancestor with PANTHER:PTN001077630 CG5626 "IPR024336:tRNA-splicing endonuclease, subunit Sen54, N-terminal, IPR024337:tRNA-splicing endonuclease, subunit Sen54" CG5626 11-Aug-17 DroID_v2017_08 Drer\tsen54 Scer\SEN54 Cele\tsen-54 Xtro\tsen54 Mmus\Tsen54 Hsap\TSEN54 viable FBgn0037265 spartin spartin http://flybase.org/reports/FBgn0037265 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab18 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype negative regulation of BMP signaling pathway ; GO:0030514 | inferred from genetic interaction with wit neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype presynaptic membrane ; GO:0042734 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay "CG12001, spartin, Spartin" "IPR009686:Senescence/spartin-associated, IPR007330:MIT" CG12001 11-Aug-17 DroID_v2017_08 "Drer\spg20b, Drer\spg20a" - Cele\spg-20 Xtro\spg20 Mmus\Spg20 Hsap\SPG20 "viable,fertile,neuroanatomy defective,neurophysiology defective,locomotor behavior defective,progressive" "NMJ bouton,supernumerary,adult brain,progressive,supernumerary | third instar larval stage" FBgn0270926 AsnS Asparagine synthetase http://flybase.org/reports/FBgn0270926 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from biological aspect of ancestor with PANTHER:PTN000206333 asparagine synthase (glutamine-hydrolyzing) activity ; GO:0004066 | inferred from biological aspect of ancestor with PANTHER:PTN000206333 asparagine biosynthetic process ; GO:0006529 | inferred from biological aspect of ancestor with PANTHER:PTN000206333 - "AsnS, AS, asparagine-synthetase, CG33486" "IPR029055:Nucleophile aminohydrolases, N-terminal, IPR006426:Asparagine synthase, glutamine-hydrolyzing, IPR001962:Asparagine synthase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR017932:Glutamine amidotransferase type 2 domain, IPR033738:Asparagine synthase, N-terminal domain" CG33486 11-Aug-17 DroID_v2017_08 Drer\asns "Scer\ASN1, Scer\YML096W, Scer\ASN2" "Cele\asns-1, Cele\asns-2" Xtro\asns Mmus\Asns Hsap\ASNS FBgn0030763 CG9782 - http://flybase.org/reports/FBgn0030763 protein_coding_gene - - - CG9782 - CG9782 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0082952 snoRNA:Me18S-A1061 snoRNA:Me18S-A1061 http://flybase.org/reports/FBgn0082952 snoRNA_gene - - - "snoRNA:Me18S-A1061, Me18S-Am1061, Me18S-A1061 (DmSnR54), CR34537, DmSnR54, Dm_18S.001" - CR34537 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035371 AhcyL1 Adenosylhomocysteinase like 1 http://flybase.org/reports/FBgn0035371 protein_coding_gene "adenosylhomocysteinase activity ; GO:0004013 | inferred from electronic annotation with InterPro:IPR000043, InterPro:IPR020082" "one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR000043, InterPro:IPR020082 S-adenosylmethionine cycle ; GO:0033353 | inferred from biological aspect of ancestor with PANTHER:PTN000602759" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000602759 "CG9977, dAhcyL1, AhcyL1" "IPR000043:Adenosylhomocysteinase-like, IPR015878:S-adenosyl-L-homocysteine hydrolase, NAD binding domain, IPR016040:NAD(P)-binding domain, IPR020082:S-adenosyl-L-homocysteine hydrolase, conserved site" CG9977 11-Aug-17 DroID_v2017_08 "Drer\ahcyl1, Drer\zgc:158222, Drer\ahcyl2, Drer\ahcy" Scer\SAH1 - "Xtro\ahcyl2, Xtro\ahcy, Xtro\ahcyl1" "Mmus\Ahcyl2, Mmus\Gm4737, Mmus\Ahcyl1, Mmus\Ahcy" "Hsap\AHCYL2, Hsap\AHCYL1, Hsap\AHCY" viable FBgn0060328 l(3)S146411b lethal (3) S146411b http://flybase.org/reports/FBgn0060328 gene - - - "1464/11, l(3)S146411b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0259309 EP-476 - http://flybase.org/reports/FBgn0259309 gene - - - EP-476 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin" FBgn0034182 SmydA-7 "SET and MYND domain containing, arthropod-specific, member 7" http://flybase.org/reports/FBgn0034182 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "SmydA-7, CG9640" - CG9640 11-Aug-17 DroID_v2017_08 "Drer\smyd2a, Drer\erlin1, Drer\erlin2, Drer\smyd2b, Drer\smyd3, Drer\smyd1a, Drer\smyd4, Drer\smyd1b" "Scer\SET5, Scer\SET6" "Cele\set-18, Cele\set-10, Cele\erl-1" "Xtro\smyd1, Xtro\erlin2, Xtro\smyd5, Xtro\erlin1, Xtro\smyd4" "Mmus\Erlin2, Mmus\Erlin1, Mmus\Smyd5, Mmus\Smyd2, Mmus\Smyd3, Mmus\Zmynd15, Mmus\Smyd4, Mmus\Smyd1" "Hsap\SMYD5, Hsap\SMYD1, Hsap\ZMYND15, Hsap\SMYD2, Hsap\ERLIN1, Hsap\SMYD4, Hsap\SMYD3" viable FBgn0034266 CG4975 - http://flybase.org/reports/FBgn0034266 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cytoplasm ; GO:0005737 | inferred from direct assay "CG4975, Atxn10" "IPR016024:Armadillo-type fold, IPR019156:Ataxin-10 domain, IPR011989:Armadillo-like helical" CG4975 11-Aug-17 DroID_v2017_08 Drer\atxn10 Scer\CTR86 - Xtro\atxn10 Mmus\Atxn10 Hsap\ATXN10 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0260297 GSd232 - http://flybase.org/reports/FBgn0260297 gene - - - GSd232 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259822 Ca-beta Ca2+-channel-protein-beta-subunit http://flybase.org/reports/FBgn0259822 protein_coding_gene high voltage-gated calcium channel activity ; GO:0008331 | inferred from biological aspect of ancestor with PANTHER:PTN000930213 voltage-gated calcium channel activity ; GO:0005245 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from biological aspect of ancestor with PANTHER:PTN000930213 regulation of voltage-gated calcium channel activity ; GO:1901385 | inferred from biological aspect of ancestor with PANTHER:PTN000930213 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype calcium-mediated signaling ; GO:0019722 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from biological aspect of ancestor with PANTHER:PTN000930213 calcium ion transmembrane transport ; GO:0070588 | inferred from mutant phenotype voltage-gated calcium channel complex ; GO:0005891 | inferred from electronic annotation with InterPro:IPR000584 voltage-gated calcium channel complex ; GO:0005891 | traceable author statement "Ca-beta, CG42403, CG6320, dmcab1, DmCa1beta, CaBeta, CG14922, CG14923, CG33305, ca-beta" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000584:Voltage-dependent calcium channel, L-type, beta subunit, IPR001452:SH3 domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit" CG42403 11-Aug-17 DroID_v2017_08 "Drer\cacnb3b, Drer\cacnb2a, Drer\cacnb2b, Drer\cacnb4b, Drer\cacnb1, Drer\cacnb3a, Drer\cacnb4a" - "Cele\ccb-1, Cele\ccb-2" "Xtro\cacnb3, Xtro\cacnb2, Xtro\cacnb4" "Mmus\Cacnb2, Mmus\Cacnb1, Mmus\Cacnb4, Mmus\Cacnb3" "Hsap\CACNB3, Hsap\CACNB1, Hsap\CACNB2, Hsap\CACNB4" DRSC03285 K 0.223235351 0.633243612 0.09161656 0.198400026 -1.625386545 -0.251280382 FBgn0263081 CG43349 - http://flybase.org/reports/FBgn0263081 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43349 - CG43349 11-Aug-17 DroID_v2017_08 - - - - - Hsap\PHGR1 FBgn0040566 CG14328 - http://flybase.org/reports/FBgn0040566 protein_coding_gene - - - CG14328 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039290 CG13654 - http://flybase.org/reports/FBgn0039290 protein_coding_gene - - plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000371278 CG13654 "IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site, IPR021910:Protein of unknown function DUF3522" CG13654 11-Aug-17 DroID_v2017_08 "Drer\tmem8c, Drer\si:dkey-84j12.1, Drer\tmem8a" - - Xtro\tmem8a "Mmus\Tmem8b, Mmus\Tmem8c, Mmus\Tmem8" "Hsap\TMEM8B, Hsap\TMEM8A, Hsap\TMEM8C" viable FBgn0044046 Ilp7 Insulin-like peptide 7 http://flybase.org/reports/FBgn0044046 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "Ilp, DILP, dilp, dilp-7, Dilp, Dilp 7, dilp7, CG13317, Ilp7, ILP7, DILP7, Ilp-7, ilp7, Dilp7, DILP-7, dILP7" IPR016179:Insulin-like CG13317 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , larval stage | third instar " " organism

, ventral nerve cord | restricted & segmentally repeated

" "large body,behavior defective,female,viable" FBgn0040777 CG14767 - http://flybase.org/reports/FBgn0040777 protein_coding_gene - - "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004687, InterPro:IPR018400" "CG8575, CG14767, dmCG14767" IPR004687:Lysosomal-associated transmembrane protein 4/5 CG14767 11-Aug-17 DroID_v2017_08 "Drer\laptm4a, Drer\laptm4b, Drer\LOC100151049" - "Cele\C05E11.3, Cele\C39D10.6" "Xtro\laptm5, Xtro\laptm4a" "Mmus\Laptm5, Mmus\Laptm4a, Mmus\Laptm4b" "Hsap\LAPTM5, Hsap\LAPTM4A, Hsap\LAPTM4B" "viable,fertile" FBgn0264644 etiolated etiolated http://flybase.org/reports/FBgn0264644 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - etiolated - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval tracheal system,eye,somatic clone" FBgn0027844 CAH1 Carbonic anhydrase 1 http://flybase.org/reports/FBgn0027844 FBgn0027926 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 carbonate dehydratase activity ; GO:0004089 | inferred from direct assay carbonate dehydratase activity ; GO:0004089 | inferred from sequence or structural similarity one-carbon metabolic process ; GO:0006730 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence model "BG:DS00941.1, CAH, CG7820, CAH1, Gh7" "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class, IPR018338:Carbonic anhydrase, alpha-class, conserved site" CG7820 11-Aug-17 DroID_v2017_08 "Drer\ca5a, Drer\ca6, Drer\ca9, Drer\cahz, Drer\ca4b, Drer\ca10a, Drer\ca14, Drer\ca15b, Drer\ca15c, Drer\car15, Drer\ca4c, Drer\si:ch211-173d10.4, Drer\ca7, Drer\ca10b, Drer\ca16b, Drer\zgc:153760, Drer\ca12, Drer\ca2, Drer\ca15a, Drer\ca4a, Drer\ptprga, Drer\ca8" - "Cele\cah-6, Cele\cah-4, Cele\cah-5, Cele\cah-3" "Xtro\ca5b, Xtro\ca6, Xtro\ca8, Xtro\ca2, Xtro\ca1, Xtro\ca10, Xtro\ca7, Xtro\ca14, Xtro\ca3, Xtro\ca12, Xtro\LOC779564, Xtro\ca4, Xtro\ca11, Xtro\car1_predicted" "Mmus\Car8, Mmus\Car2, Mmus\Ptprg, Mmus\Car4, Mmus\Car11, Mmus\Car15, Mmus\Car9, Mmus\Car5a, Mmus\Car14, Mmus\Car10, Mmus\Car5b, Mmus\Car1, Mmus\Car7, Mmus\Car12, Mmus\Car6, Mmus\Car13, Mmus\Car3" "Hsap\CA10, Hsap\CA5B, Hsap\CA9, Hsap\CA6, Hsap\CA4, Hsap\CA14, Hsap\CA5A, Hsap\CA11, Hsap\CA8, Hsap\CA2, Hsap\CA13, Hsap\CA7, Hsap\CA12, Hsap\CA1, Hsap\PTPRG, Hsap\CA3" FBgn0063083 pncr015:3L putative noncoding RNA 015:3L http://flybase.org/reports/FBgn0063083 non_protein_coding_gene - - - "CR33948, BcDNA:LP12023, pncr015:3L" - CR33948 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033884 CG13344 - http://flybase.org/reports/FBgn0033884 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN001408403 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1890215 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:1890215 positive regulation of NF-kappaB transcription factor activity ; GO:0051092 | inferred from biological aspect of ancestor with PANTHER:PTN000324465 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001408403 "CG13344, anon-EST:GressD1, anon-EST:GreesD1" "IPR001841:Zinc finger, RING-type, IPR006575:RWD domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13344 11-Aug-17 DroID_v2017_08 Drer\rnf25 - Cele\Y53G8AR.5 Xtro\rnf25 Mmus\Rnf25 Hsap\RNF25 "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0001539 l(1)14DEa lethal (1) 14DEa http://flybase.org/reports/FBgn0001539 - gene - - - l(1)14DEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020387 Pdz Pdz http://flybase.org/reports/FBgn0020387 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available - Pdz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263107 bft bereft http://flybase.org/reports/FBgn0263107 miRNA_gene molecular_function ; GO:0003674 | no biological data available chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with hid gene silencing by miRNA ; GO:0035195 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "miR-263a, mir-263a, dme-mir-263a, 263a, bft, CR31863, CR42938, CR33580, miR-263, dme-miR-263a" - CR42938 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,viable,recessive,visible,lethal - all die before end of P-stage,some die during pharate adult stage,fertile" "interommatidial bristle,orbital bristle,vertical bristle,postvertical bristle,humeral bristle,dorsocentral bristle,postalar bristle,scutellar bristle,eye,wing,wing margin bristle,interommatidial bristle & socket,sensillum trichodeum,sensillum trichodeum & trichogen cell" FBgn0065335 l(2)SH1856 lethal (2) SH1856 http://flybase.org/reports/FBgn0065335 gene - - - "l(2)SH1856, l(2)SH2 1856" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084678 vto vertigo http://flybase.org/reports/FBgn0084678 gene - adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype - "O151, vto" - - 11-Aug-17 DroID_v2017_08 - - - - - - "locomotor behavior defective,recessive" FBgn0035610 Lkr Leucokinin receptor http://flybase.org/reports/FBgn0035610 protein_coding_gene neuropeptide Y receptor activity ; GO:0004983 | inferred from electronic annotation with InterPro:IPR000611 leucokinin receptor activity ; GO:0042071 | inferred from direct assay neuropeptide receptor activity ; GO:0008188 | inferred from sequence model "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000611 positive regulation of cytosolic calcium ion concentration ; GO:0007204 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model negative regulation of feeding behavior ; GO:2000252 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with TkR99D integral component of membrane ; GO:0016021 | inferred from sequence model basolateral plasma membrane ; GO:0016323 | inferred from direct assay "CG10626, DLKR, anon-WO0170980.119, anon-WO0170980.118, anon-WO0131005.17, Lkr, dLKR, LK-R, LkR, lkr, LKR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000611:Neuropeptide Y receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG10626 11-Aug-17 DroID_v2017_08 "Drer\tacr1b, Drer\prokr1a, Drer\npffr1l1, Drer\tacr2, Drer\prlhr2b, Drer\prlhr2a, Drer\tacr3a, Drer\npffr2a, Drer\npffr1l2, Drer\tacr3l, Drer\prokr1b, Drer\LOC100333270, Drer\tacr1a" - "Cele\tkr-1, Cele\npr-22, Cele\tkr-3, Cele\K01A12.3, Cele\gtr-1" "Xtro\prokr1, Xtro\tacr1, Xtro\prokr2, Xtro\tacr3, Xtro\LOC100493271, Xtro\LOC100497124" "Mmus\Tacr2, Mmus\Prokr1, Mmus\Prokr2, Mmus\Pgr15l, Mmus\Tacr1, Mmus\Tacr3, Mmus\Npy1r" "Hsap\TACR3, Hsap\PROKR1, Hsap\TACR2, Hsap\NPY1R, Hsap\TACR1" viable FBgn0266735 CR45208 - http://flybase.org/reports/FBgn0266735 non_protein_coding_gene - - - CR45208 - CR45208 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017483 Sxl::w Sxl::w http://flybase.org/reports/FBgn0017483 - engineered_fusion_gene - - - Sxl::w - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002927 Ndw Nicked wing http://flybase.org/reports/FBgn0002927 - gene - - - Ndw - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,cold sensitive,lethal,recessive" FBgn0085324 CG34295 - http://flybase.org/reports/FBgn0085324 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - CG34295 "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34295 11-Aug-17 DroID_v2017_08 - - - Xtro\tpsg1 Mmus\Prss27 Hsap\TMPRSS11B FBgn0267117 CR45557 - http://flybase.org/reports/FBgn0267117 non_protein_coding_gene - - - CR45557 - CR45557 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020795 oculus-parvus oculus parvus http://flybase.org/reports/FBgn0020795 - gene - - - "opa, oculus-parvus" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye FBgn0004965 coq coquilled http://flybase.org/reports/FBgn0004965 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available coq - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect,some die during immature adult stage" "wing,ovary,maternal effect,egg" FBgn0259821 CG42402 - http://flybase.org/reports/FBgn0259821 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR000922 - - "CG42402, CG12453, CG41358" IPR000922:D-galactoside/L-rhamnose binding SUEL lectin domain CG42402 11-Aug-17 DroID_v2017_08 "Drer\zgc:153499, Drer\si:dkeyp-46h3.2, Drer\si:ch211-66i15.5, Drer\si:dkeyp-46h3.8, Drer\si:dkey-90l23.1, Drer\eva1c, Drer\LOC564755, Drer\zgc:136410, Drer\zgc:171776, Drer\LOC100536038, Drer\si:ch73-335m24.2, Drer\si:ch1073-75o15.3, Drer\si:ch1073-75o15.4, Drer\LOC101882949, Drer\si:ch211-145c1.1" - Cele\eva-1 Xtro\eva1c Mmus\Eva1c Hsap\EVA1C viable FBgn0086303 proj projectile http://flybase.org/reports/FBgn0086303 gene - filopodium assembly ; GO:0046847 | inferred from mutant phenotype - proj - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite & filopodium & larva FBgn0266101 CG44838 - http://flybase.org/reports/FBgn0266101 protein_coding_gene - - - "CG44838, CG32043, CG18632, CG3628, anon-WO0118547.427, anon-WO0118547.368, CG14180" IPR015943:WD40/YVTN repeat-like-containing domain CG44838 11-Aug-17 DroID_v2017_08 Drer\ostf1 - Cele\Y106G6H.14 - Mmus\Ostf1 Hsap\OSTF1 DRSC10179 EK -0.71726897 -1.492336756 0.314343695 -1.558680022 1.658581272 0.790585339 FBgn0266486 CG45085 - http://flybase.org/reports/FBgn0266486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45085, Dromel_CG8026_FBtr0088611_uORF" - CG45085 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034114 CG4282 - http://flybase.org/reports/FBgn0034114 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG4282 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG4282 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-30k6.5, Drer\prdm10, Drer\zgc:153116, Drer\prdm5" - "Cele\ZK686.5, Cele\H16D19.3, Cele\lsy-2, Cele\Y37F4.6, Cele\T20H4.2, Cele\Y55F3AM.14, Cele\T07D10.3" "Xtro\znf142, Xtro\prdm5" "Mmus\Prdm10, Mmus\Zfp386, Mmus\Zfy1, Mmus\Zfy2" "Hsap\ZNF521, Hsap\PRDM5, Hsap\PRDM10, Hsap\ZNF805, Hsap\PRDM15, Hsap\ZNF100" viable FBgn0032331 CG14913 - http://flybase.org/reports/FBgn0032331 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model CG14913 - CG14913 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011865 tRNA:Gly-GCC-1-7 transfer RNA:Glycine-GCC 1-7 http://flybase.org/reports/FBgn0011865 "FBgn0003779, FBgn0051981, FBgn0060221" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "BG:DS04641.6, AE002690.trna16-GlyGCC, tRNA:G:GCC:AE002690-d, CR31981, tRNA:gly3:35Bd, tRNA[Gly-GCC], chr2L.trna25-GlyGCC, tRNA-Gly-GCC-1-7, tRNA:Gly-GCC-1-7, tRNA:G3:35Bd, GGC" - CR31981 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001570 l(1)20Cb lethal (1) 20Cb http://flybase.org/reports/FBgn0001570 - gene - - - "l(1)Q463, l(1)20, Q463, 20, lQ463, l20, l(1)20Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage,polyphasic" FBgn0265741 CR44548 - http://flybase.org/reports/FBgn0265741 non_protein_coding_gene - - - "CR44548, lincRNA.515" - CR44548 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030480 Tim9a Tim9a http://flybase.org/reports/FBgn0030480 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:Q9Y5J7 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q9Y5J7 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q9Y5J7 "Tim9, CG1660, Tim9a" IPR004217:Tim10/DDP family zinc finger CG1660 11-Aug-17 DroID_v2017_08 "Drer\timm9, Drer\timm10b" Scer\TIM9 "Cele\tin-9.1, Cele\tin-9.2" Xtro\timm9 "Mmus\Timm9, Mmus\Timm10b" "Hsap\TIMM9, Hsap\TIMM10B" "lethal,recessive,viable" FBgn0001729 l(1)ESHS50 lethal (1) ESHS50 http://flybase.org/reports/FBgn0001729 - gene - - - l(1)ESHS50 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065976 iab4-5.as iab4-5.as http://flybase.org/reports/FBgn0065976 gene - - - "4-5 as, iab4-5.as" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053929 CR33929 - http://flybase.org/reports/FBgn0053929 pseudogene_attribute - - - "CR33929, CG33929" - CR33929 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065803 l(2)SH0400 lethal (2) SH0400 http://flybase.org/reports/FBgn0065803 gene - - - "l(2)SH0400, l(2)SH2 0400" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036950 CG6996 - http://flybase.org/reports/FBgn0036950 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG6996 IPR002557:Chitin binding domain CG6996 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\C39D10.7, Cele\R02F2.4, Cele\cpg-2, Cele\cpg-1" - - Hsap\MATN2 viable FBgn0000584 Erect Erect http://flybase.org/reports/FBgn0000584 - gene - - - "Erect, Er" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "posterior scutellar bristle,wing" FBgn0038857 Bdbt Bride of doubletime http://flybase.org/reports/FBgn0038857 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with dco peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 FK506 binding ; GO:0005528 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 regulation of post-translational protein modification ; GO:1901873 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 regulation of protein catabolic process ; GO:0042176 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG17282, Bdbt, bdbt" "IPR011990:Tetratricopeptide-like helical domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type" CG17282 11-Aug-17 DroID_v2017_08 "Drer\fkbp10b, Drer\fkbp7, Drer\fkbp9, Drer\fkbp10a, Drer\fkbp2, Drer\fkbp14" - "Cele\fkb-5, Cele\fkb-4, Cele\fkb-3, Cele\fkb-1" - "Mmus\Fkbp14, Mmus\Fkbp9, Mmus\Fkbp2, Mmus\Fkbp7, Mmus\Fkbp10" "Hsap\FKBP9, Hsap\FKBP7, Hsap\FKBP2, Hsap\FKBP14, Hsap\FKBP10" "viable,visible,locomotor rhythm defective" "trichogen cell,supernumerary,tormogen cell,mesothoracic tergum" DRSC15218 E 0.306965522 -0.261764955 1.643426628 0.387140507 0.427029056 0.388126594 FBgn0069960 CG41053 - http://flybase.org/reports/FBgn0069960 protein_coding_gene - - - CG41053 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283508 nw narrow http://flybase.org/reports/FBgn0283508 protein_coding_gene - regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype - "nw, CG43164, lance, Bla, CG33006, CG18431, CG4844a, CG4844, anon2D7, anon-EST:fe2D7, CG4844b" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG43164 11-Aug-17 DroID_v2017_08 - - "Cele\clec-50, Cele\clec-86" - - Hsap\REG1A DRSC06896 K -0.95973403 -0.697151696 -0.336705308 1.314712154 2.231660242 0.931839492 FBgn0005286 mei-S51 meiotic from via Salaria 51 http://flybase.org/reports/FBgn0005286 - gene molecular_function ; GO:0003674 | no biological data available female meiotic division ; GO:0007143 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mei-S51 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,female" FBgn0082997 snoRNA:Psi28S-1232 snoRNA:Psi28S-1232 http://flybase.org/reports/FBgn0082997 snoRNA_gene - - - "snoRNA:Psi28S-1232, Psi28S-1232, psi28S-1232, Psi 28S-1232, CR34592, psi-28S-1232" - CR34592 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263863 mRpL45 mitochondrial ribosomal protein L45 http://flybase.org/reports/FBgn0263863 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9BRJ2 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9BRJ2 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CG6949, mRpL45, MRP-L45, l(3)dsl-8, l(3)dsl8, l(3)A8, XI-2, l(3)SG61" "IPR032710:NTF2-like domain, IPR007379:Tim44-like domain" CG6949 11-Aug-17 DroID_v2017_08 Drer\mrpl45 Scer\KRE29 Cele\mrpl-45 Xtro\mrpl45 Mmus\Mrpl45 Hsap\MRPL45 DRSC16146 E -0.2764334 0.171994131 -1.573378247 -0.246093997 -0.268290492 0.071577735 FBgn0259622 B0066 - http://flybase.org/reports/FBgn0259622 gene - - - B0066 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0264816 koko kokopelli http://flybase.org/reports/FBgn0264816 protein_coding_gene cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of phosphorylation of RNA polymerase II C-terminal domain ; GO:1901409 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 "koko, CG7683, CG31232, CG44010" "IPR028759:Cyclin-related protein FAM58, IPR013763:Cyclin-like, IPR006671:Cyclin, N-terminal" CG44010 11-Aug-17 DroID_v2017_08 Drer\fam58a "Scer\SSN8, Scer\BUR2" - Xtro\fam58a Mmus\Fam58b Hsap\FAM58A "viable,fertile" FBgn0030970 CG7326 - http://flybase.org/reports/FBgn0030970 protein_coding_gene - - - CG7326 IPR019193:Ubiquitin-conjugating enzyme E2-binding protein CG7326 11-Aug-17 DroID_v2017_08 Drer\ube3d Scer\YJR141W - Xtro\ube3d Mmus\Ube2cbp Hsap\UBE3D "lethal,recessive,viable" FBgn0003152 Pigmentless Pigmentless http://flybase.org/reports/FBgn0003152 - gene - - - "Pigmentless, Ps" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,body color defective,dominant,female limited" adult abdomen & cuticle | female FBgn0262780 Su(E1)-N - http://flybase.org/reports/FBgn0262780 gene - - - Su(E1)-N - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013260 E(var)48 E(var)48 http://flybase.org/reports/FBgn0013260 - gene - - - E(var)48 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0039226 Ude Uracil-DNA degrading factor http://flybase.org/reports/FBgn0039226 protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay uracil DNA N-glycosylase activity ; GO:0004844 | NOT inferred from direct assay RNA binding ; GO:0003723 | inferred from direct assay double-stranded RNA-specific ribonuclease activity ; GO:0032296 | NOT inferred from direct assay DNA catabolic process ; GO:0006308 | inferred from direct assay pupation ; GO:0035074 | inferred from expression pattern - "UDE, Ude, CG18410" - CG18410 11-Aug-17 DroID_v2017_08 - - Cele\F14F7.5 - - - "viable,fertile" FBgn0004007 we wee http://flybase.org/reports/FBgn0004007 - gene - - - we - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,poor,small body" "eye,macrochaeta,wing" FBgn0053458 CG33458 - http://flybase.org/reports/FBgn0053458 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG33458 "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family" CG33458 11-Aug-17 DroID_v2017_08 "Drer\prss56, Drer\masp2" - Cele\try-3 - "Mmus\Prss56, Mmus\Egfbp2" Hsap\PRSS56 viable FBgn0014197 l(1)14Cd lethal (1) 14Cd http://flybase.org/reports/FBgn0014197 - gene - - - "l(1)14Ce, l(1)14Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "ovariole,germline clone" FBgn0065197 l(2)SH2320 lethal (2) SH2320 http://flybase.org/reports/FBgn0065197 gene - - - "l(2)SH2320, l(2)SH2 2320" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266505 s-334 - http://flybase.org/reports/FBgn0266505 gene - - - s-334 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082632 S(CycE[JP])2.6 S(CycE[JP])2.6 http://flybase.org/reports/FBgn0082632 gene - - - S(CycE[JP])2.6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264821 CR44029 - http://flybase.org/reports/FBgn0264821 non_protein_coding_gene - - - CR44029 - CR44029 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082617 S(CycE[JP])68S10 S(CycE[JP])68S10 http://flybase.org/reports/FBgn0082617 gene - - - "68S10, S(CycE[JP])68S10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083305 E(smoDN)1551 Enhancer of smoDN 1551 http://flybase.org/reports/FBgn0083305 gene - - - E(smoDN)1551 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023134 WppI White prepupal locus I http://flybase.org/reports/FBgn0023134 - gene - - - "37, 22A, 10, WppI" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262970 CR43281 - http://flybase.org/reports/FBgn0262970 pseudogene_attribute - - - CR43281 - CR43281 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028176 l(3)S026115b lethal (3) S026115b http://flybase.org/reports/FBgn0028176 gene - - - "0261/15, l(3)S026115, l(3)S026115b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0063398 Stalker2\ORF1 Stalker2 element ORF1 http://flybase.org/reports/FBgn0063398 transposable_element_gene - - - "rom\ORF1, Stalker2\ORF1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040082 p82 p82 http://flybase.org/reports/FBgn0040082 gene - - - p82 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052666 Drak Death-associated protein kinase related http://flybase.org/reports/FBgn0052666 protein_coding_gene protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678761 ATP binding ; GO:0005524 | inferred from biological aspect of ancestor with PANTHER:PTN000678761 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | inferred from genetic interaction with Rok protein phosphorylation ; GO:0006468 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678761 "CG1760, EP(X)1452, CG11713, EP1452, Drak, CG32666, drak" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG32666 11-Aug-17 DroID_v2017_08 "Drer\zgc:153952, Drer\mylk4a, Drer\camkva, Drer\mylk4b, Drer\ttnb, Drer\si:ch73-60h1.1, Drer\camkvb, Drer\camk1ga, Drer\pskh1, Drer\trioa, Drer\dapk2b, Drer\camkvl, Drer\triob, Drer\dapk3, Drer\stk17b, Drer\pnck, Drer\camk1db, Drer\capsla, Drer\uhmk1, Drer\camk1da, Drer\capslb, Drer\camk1b, Drer\si:dkey-240h12.4, Drer\camk1gb, Drer\spegb, Drer\stk33, Drer\camk1a, Drer\camk4, Drer\si:ch211-27e6.1, Drer\dapk1, Drer\dapk2a, Drer\mylk3, Drer\stk17a" "Scer\PKH2, Scer\TDA1, Scer\RCK1, Scer\RCK2, Scer\IKS1, Scer\PKH1, Scer\CMK2, Scer\MEK1, Scer\RAD53, Scer\CMK1" Cele\F32D8.1 "Xtro\dapk2, Xtro\mylk3, Xtro\capsl, Xtro\kalrn, Xtro\dclk2, Xtro\pskh1, Xtro\mark2, Xtro\camk1d, Xtro\camk4, Xtro\camkv, Xtro\stk17a, Xtro\pnck, Xtro\stk33, Xtro\dapk3, Xtro\camk1, Xtro\camk1g, Xtro\trio, Xtro\caps, Xtro\pskh2, Xtro\mylk4, Xtro\dapk1" "Mmus\Dclk2, Mmus\Dclk1, Mmus\Pnck, Mmus\Capsl, Mmus\Mapk7, Mmus\Trio, Mmus\Mylk2, Mmus\Dapk1, Mmus\Dapk3, Mmus\Uhmk1, Mmus\Speg, Mmus\Stk17b, Mmus\Dapk2, Mmus\Mylk3, Mmus\Pskh1, Mmus\Camk1, Mmus\Camk1g, Mmus\Obscn, Mmus\Mylk4, Mmus\Caps2, Mmus\Camkv, Mmus\Camk1d, Mmus\Stk33, Mmus\Camk4" "Hsap\DAPK1, Hsap\MYLK3, Hsap\PSKH2, Hsap\TRIO, Hsap\UHMK1, Hsap\SPEG, Hsap\PNCK, Hsap\DAPK2, Hsap\DCLK1, Hsap\CAPS2, Hsap\MYLK4, Hsap\CAMK4, Hsap\NEK4, Hsap\STK17A, Hsap\MYLK2, Hsap\PSKH1, Hsap\DAPK3, Hsap\STK33, Hsap\CAMK1G, Hsap\CAPS, Hsap\STK17B, Hsap\CAMK1, Hsap\OBSCN, Hsap\CAMKV, Hsap\CAPSL, Hsap\CAMK1D" "viable,fertile,visible,lethal" "wing,metathoracic leg,chaeta,supernumerary" FBgn0260044 33R6 - http://flybase.org/reports/FBgn0260044 gene - - - 33R6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0000707 fltM flight defective M http://flybase.org/reports/FBgn0000707 - gene - - - fltM - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0023045 l(1)3Bg lethal (1) 3Bg http://flybase.org/reports/FBgn0023045 - gene - - - "B2/50.8, l(1)3Bg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035911 CG6638 - http://flybase.org/reports/FBgn0035911 protein_coding_gene flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786 isovaleryl-CoA dehydrogenase activity ; GO:0008470 | inferred from sequence or structural similarity with UniProtKB:P26440 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091, InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786 leucine catabolic process ; GO:0006552 | inferred from sequence or structural similarity with UniProtKB:P26440" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P26440 CG6638 "IPR006089:Acyl-CoA dehydrogenase, conserved site, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR034183:Isovaleryl-CoA dehydrogenase" CG6638 11-Aug-17 DroID_v2017_08 "Drer\acad9, Drer\acadl, Drer\acadvl, Drer\acads, Drer\acad8, Drer\acadm, Drer\ivd" - "Cele\acdh-8, Cele\acdh-9, Cele\acdh-4, Cele\acdh-1, Cele\acdh-7, Cele\ivd-1" "Xtro\acadl, Xtro\acad8, Xtro\acadsb, Xtro\ivd, Xtro\acad9, Xtro\acads, Xtro\acadm" "Mmus\Acad8, Mmus\Acad9, Mmus\Acads, Mmus\Ivd, Mmus\Acadl, Mmus\Acadvl, Mmus\Acadsb, Mmus\Acadm" "Hsap\ACAD9, Hsap\ACADVL, Hsap\IVD, Hsap\ACADM, Hsap\ACADS, Hsap\ACADL, Hsap\ACADSB, Hsap\ACAD8" FBgn0004679 Esm Enhancer of split mimic http://flybase.org/reports/FBgn0004679 - gene - - - Esm - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028839 C5 C5 http://flybase.org/reports/FBgn0028839 gene - - - C5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "locomotor behavior defective,dominant,viable" FBgn0053451 5SrRNA:CR33451 5SrRNA:CR33451 http://flybase.org/reports/FBgn0053451 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33451, 5SrRNA:CR33451" - CR33451 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266580 Gp210 Glycoprotein 210 kDa http://flybase.org/reports/FBgn0266580 protein_coding_gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype protein import into nucleus ; GO:0006606 | inferred from sequence or structural similarity with SGD:S000004736 olfactory learning ; GO:0008355 | inferred from mutant phenotype nuclear pore organization ; GO:0006999 | inferred from sequence or structural similarity with SGD:S000004736 nuclear pore transmembrane ring ; GO:0070762 | inferred from sequence or structural similarity with SGD:S000004736 nuclear pore nuclear basket ; GO:0044615 | inferred from direct assay nuclear pore inner ring ; GO:0044611 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "gp210, CG14467, CG7897, Gp210, GP210, lyadi, gp210[[D]], gp188, Gp188, Dm gp210" IPR008964:Invasin/intimin cell-adhesion fragments CG7897 11-Aug-17 DroID_v2017_08 Drer\nup210 - Cele\npp-12 Xtro\nup210 "Mmus\Nup210l, Mmus\Nup210" "Hsap\NUP210L, Hsap\NUP210" embryonic stage | early FBgn0265200 CR44260 - http://flybase.org/reports/FBgn0265200 non_protein_coding_gene - - - "CR44260, lincRNA.714" - CR44260 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000305 ch-b chilblained b http://flybase.org/reports/FBgn0000305 - gene - - - ch-b - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" tarsal segment FBgn0003203 rar3 radiation-resistant on 3 http://flybase.org/reports/FBgn0003203 - gene - - - rar3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021912 l(2)k11502 lethal (2) k11502 http://flybase.org/reports/FBgn0021912 - gene - - - l(2)k11502 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260094 2L1923 - http://flybase.org/reports/FBgn0260094 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L1923 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0014300 l(3)7-19 lethal (3) 7-19 http://flybase.org/reports/FBgn0014300 - gene - - - l(3)7-19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" macrochaeta FBgn0020782 skarped-wing skarped wing http://flybase.org/reports/FBgn0020782 - gene - - - skarped-wing - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile" wing FBgn0260985 RfC4 Replication factor C subunit 4 http://flybase.org/reports/FBgn0260985 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from sequence or structural similarity with SGD:S000005454 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000186208 DNA binding ; GO:0003677 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from sequence or structural similarity with SGD:S000005454 DNA strand elongation involved in DNA replication ; GO:0006271 | traceable author statement mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype DNA repair ; GO:0006281 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype leading strand elongation ; GO:0006272 | inferred from sequence or structural similarity with SGD:S000005454 DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype DNA replication checkpoint ; GO:0000076 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype DNA replication ; GO:0006260 | traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA replication factor C complex ; GO:0005663 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from sequence or structural similarity with SGD:S000005454 Elg1 RFC-like complex ; GO:0031391 | inferred from direct assay "RfC40, RfC4, l(3)Rfc4, CG14999, l(3)e20, DmRFC4, Rfc4, l(3)dsl-1, l(3)dsl1, l(3)A1, l(3)SG13, 154910_at, Rfc40, l(3)64Ai, rfc4, l(3)rfc40, rfc[40], l(3)SH17, rfc, BEST:GH24992, rfc40, RFC40" "IPR003593:AAA+ ATPase domain, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR013748:Replication factor C, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003959:ATPase, AAA-type, core" CG14999 11-Aug-17 DroID_v2017_08 "Drer\rfc2, Drer\rfc5" Scer\RFC4 "Cele\F44B9.8, Cele\rfc-2, Cele\rfc-4" "Xtro\rfc2, Xtro\rfc5, Xtro\rfc4" "Mmus\Rfc5, Mmus\Rfc2, Mmus\Rfc4" "Hsap\RFC5, Hsap\RFC2" embryonic stage FBgn0067319 CG40450 - http://flybase.org/reports/FBgn0067319 protein_coding_gene - - - CG40450 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005455 l(1)v451 lethal (1) v451 http://flybase.org/reports/FBgn0005455 - gene - - - "l(1)451, l(1)v451" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,lethal,male,lethal - all die before end of larval stage,maternal effect,some die during larval stage" "egg chamber,germline clone,maternal effect" FBgn0261625 GLS Glutaminase http://flybase.org/reports/FBgn0261625 protein_coding_gene glutaminase activity ; GO:0004359 | inferred from sequence or structural similarity with UniProtKB:O94925 glutaminase activity ; GO:0004359 | inferred from biological aspect of ancestor with PANTHER:PTN000283994 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype glutamate biosynthetic process ; GO:0006537 | inferred from biological aspect of ancestor with PANTHER:PTN000283994 glutamine catabolic process ; GO:0006543 | inferred from biological aspect of ancestor with PANTHER:PTN000283994 glutamine metabolic process ; GO:0006541 | inferred from sequence or structural similarity with UniProtKB:O94925 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O94925 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000283995 "GLS, CG42708, CG8772, CG8872" "IPR015868:Glutaminase, IPR002110:Ankyrin repeat, IPR012338:Beta-lactamase/transpeptidase-like, IPR020683:Ankyrin repeat-containing domain" CG42708 11-Aug-17 DroID_v2017_08 "Drer\glsl, Drer\glsb, Drer\gls2a, Drer\si:dkey-102c8.2, Drer\gls2b, Drer\glsa" - "Cele\glna-3, Cele\glna-2, Cele\glna-1" "Xtro\gls, Xtro\gls2" "Mmus\Gls, Mmus\Gls2" "Hsap\GLS, Hsap\GLS2" viable FBgn0039411 dysf dysfusion http://flybase.org/reports/FBgn0039411 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | traceable author statement RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000548738 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with ss protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with tgo transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from physical interaction with tgo sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with ss positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype morphogenesis of an epithelial fold ; GO:0060571 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from direct assay branch fusion, open tracheal system ; GO:0035147 | inferred from expression pattern inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0003700,GO:0043565 protein complex ; GO:0043234 | inferred from physical interaction with tgo nucleus ; GO:0005634 | inferred by curator from GO:0003700" "Dys, CG14554, CG12561, CG14553, CG14552, CG32474, dNXFL, dysf, dys, NXFL" "IPR000014:PAS domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG32474 11-Aug-17 DroID_v2017_08 "Drer\npas4b, Drer\npas4a" - "Cele\cky-1, Cele\ahr-1" Xtro\npas4 Mmus\Npas4 "Hsap\SIM2, Hsap\NPAS4" "lethal,recessive" "embryonic/larval ganglionic branch,embryonic/larval lateral trunk,embryonic/larval dorsal branch,embryonic/larval dorsal trunk,ganglionic branch primordium | embryonic stage 16,lateral trunk primordium | embryonic stage 16,dorsal branch primordium | embryonic stage 16,dorsal trunk primordium | embryonic stage 16,visceral branch | embryonic stage 16" DRSC14895 E 0.235356986 -1.396830861 -0.305381765 -2.727490111 -0.17969087 -0.094437653 FBgn0052053 CG32053 - http://flybase.org/reports/FBgn0052053 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "CG6645, CG32053" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG32053 11-Aug-17 DroID_v2017_08 "Drer\slc2a13b, Drer\slc2a6, Drer\slc2a8, Drer\LOC101882338, Drer\slc2a10, Drer\slc2a12" "Scer\MAL11, Scer\HXT2, Scer\HXT6, Scer\HXT17, Scer\ITR2, Scer\HXT15, Scer\HXT14, Scer\VBA3, Scer\AZR1, Scer\HXT10, Scer\HXT5, Scer\ENB1, Scer\YDL199C, Scer\HXT13, Scer\SNF3, Scer\HXT4, Scer\GEX1, Scer\HXT7, Scer\YDR387C, Scer\GEX2, Scer\ITR1, Scer\MAL31, Scer\VBA2, Scer\MPH2, Scer\HXT9, Scer\YMR279C, Scer\ATR1, Scer\HXT8, Scer\MPH3, Scer\SGE1, Scer\HXT16, Scer\HXT1, Scer\VBA4, Scer\GAL2, Scer\HXT11, Scer\VBA1, Scer\STL1, Scer\VBA5, Scer\YFL040W, Scer\RGT2, Scer\HXT3" "Cele\hmit-1.2, Cele\fgt-1" "Xtro\slc2a12, Xtro\slc2a10, Xtro\slc2a8, Xtro\slc2a6" "Mmus\Slc2a10, Mmus\Slc2a6, Mmus\Slc2a8, Mmus\Slc2a12, Mmus\Slc2a13" "Hsap\SLC2A12, Hsap\SLC2A6, Hsap\SLC2A10, Hsap\SLC2A8, Hsap\SLC2A13" "partially lethal - majority die,some die during pupal stage" FBgn0259163 CG42268 - http://flybase.org/reports/FBgn0259163 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "CG42268, CG32044, CG6740, CG14170, CG32046" - CG42268 11-Aug-17 DroID_v2017_08 - - - - - - DRSC10171 IE 2.294236057 1.919991562 2.039172495 -1.637676671 0.864804219 1.482798318 FBgn0243514 eater eater http://flybase.org/reports/FBgn0243514 protein_coding_gene scavenger receptor activity ; GO:0005044 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from direct assay "immune response ; GO:0006955 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype positive regulation of phagocytosis ; GO:0050766 | inferred from mutant phenotype phagocytosis, recognition ; GO:0006910 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype positive regulation of cell-substrate adhesion ; GO:0010811 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype" cell surface ; GO:0009986 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "eater, Eater, CG6124, CT19227, C901-like, Dmel_CG6124" "IPR000742:EGF-like domain, IPR003341:Cysteine rich repeat, tripleX" CG6124 11-Aug-17 DroID_v2017_08 "Drer\wu:fj11g02, Drer\si:ch1073-110a20.2, Drer\angpt4, Drer\angptl1a, Drer\megf6a, Drer\angptl2b, Drer\si:ch1073-110a20.3, Drer\megf10, Drer\angpt1, Drer\figf, Drer\zgc:171687, Drer\dkk2, Drer\fibcd1, Drer\fgb, Drer\ltbp3, Drer\scube3, Drer\tnr, Drer\esm1, Drer\si:ch1073-110a20.1, Drer\si:ch211-157b11.8, Drer\tnfaip6, Drer\tnc, Drer\LOC100007488, Drer\ccbe1, Drer\si:ch211-203k16.3, Drer\si:zfos-2330d3.3, Drer\angptl6, Drer\fgl2a, Drer\angpt2b, Drer\megf6b, Drer\scube1, Drer\megf11, Drer\scarf1, Drer\vegfc, Drer\fgg, Drer\zgc:158328, Drer\angptl3, Drer\pear1, Drer\tnw, Drer\fga, Drer\tnxba, Drer\fgl2b, Drer\angptl5, Drer\angptl4, Drer\scube2, Drer\zgc:194887, Drer\zmp:0000000846, Drer\angptl2a, Drer\vegfab, Drer\si:zfos-2330d3.8, Drer\si:zfos-2330d3.6, Drer\si:zfos-2330d3.1, Drer\dkk1a, Drer\si:ch211-287a12.9" - "Cele\Y26D4A.12, Cele\pqn-13, Cele\K10D3.4, Cele\B0393.5, Cele\arg-1, Cele\ZK1193.3, Cele\M195.2, Cele\ZC504.1, Cele\Y69H2.3, Cele\W05B2.2, Cele\Y34B4A.5, Cele\Y43C5A.2, Cele\F07H5.8, Cele\abu-4, Cele\abu-10, Cele\Y69H2.10, Cele\T15B7.1, Cele\ensh-1, Cele\R09H10.5, Cele\C08G9.2, Cele\F35A5.4" "Xtro\fibcd1, Xtro\LOC100488177, Xtro\stab2, Xtro\fgl2, Xtro\tnr, Xtro\tnfaip6, Xtro\angptl3, Xtro\angptl4, Xtro\fcn3, Xtro\fcn1, Xtro\fgg, Xtro\mfap4, Xtro\fgl1, Xtro\fga, Xtro\angptl2, Xtro\fgb, Xtro\megf11, Xtro\scube1, Xtro\LOC100497330, Xtro\fcn2, Xtro\tnn, Xtro\tnc, Xtro\LOC100491105, Xtro\angpt4, Xtro\angpt1, Xtro\tnxb, Xtro\angptl5" "Mmus\Megf11, Mmus\Fgg, Mmus\Fgl2, Mmus\Fgl1, Mmus\Angptl7, Mmus\Fcnb, Mmus\Angptl6, Mmus\Tnn, Mmus\Scube3, Mmus\Esm1, Mmus\Tnr, Mmus\Egfem1, Mmus\Pear1, Mmus\Angptl3, Mmus\Dkk2, Mmus\Scube1, Mmus\Angptl1, Mmus\Fibcd1, Mmus\Stab1, Mmus\Megf6, Mmus\Angptl2, Mmus\Vegfd, Mmus\Tnxb, Mmus\Scube2, Mmus\Fgb, Mmus\Megf10, Mmus\Scarf1, Mmus\Tnc, Mmus\Angpt1, Mmus\Fga, Mmus\Angpt2, Mmus\Fcna, Mmus\Mfap4, Mmus\Angptl4, Mmus\Vegfc, Mmus\Dkk3, Mmus\Tnfaip6, Mmus\Angpt4" "Hsap\MEGF11, Hsap\FIBCD1, Hsap\VEGFD, Hsap\FGB, Hsap\DKK2, Hsap\FCN2, Hsap\ANGPTL7, Hsap\SCARF1, Hsap\SCUBE3, Hsap\TNXB, Hsap\FGG, Hsap\SCARF2, Hsap\TNC, Hsap\ANGPTL3, Hsap\TNN, Hsap\FCN3, Hsap\ANGPT4, Hsap\FGA, Hsap\SCUBE2, Hsap\ANGPT1, Hsap\FGL2, Hsap\ANGPT2, Hsap\VEGFC, Hsap\SCUBE1, Hsap\ANGPTL1, Hsap\ANGPTL6, Hsap\TNR, Hsap\ANGPTL2, Hsap\MEGF6, Hsap\PEAR1, Hsap\MEGF10, Hsap\TNFAIP6, Hsap\ANGPTL4, Hsap\FGL1, Hsap\ANGPTL5" FBgn0011620 l(1)K49c28-A3 lethal (1) K49c28-A3 http://flybase.org/reports/FBgn0011620 - gene - - - l(1)K49c28-A3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259409 EP-160 - http://flybase.org/reports/FBgn0259409 gene - - - EP-160 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0262373 mir-9a mir-9a stem loop http://flybase.org/reports/FBgn0262373 miRNA_gene - sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from direct assay wing disc development ; GO:0035220 | inferred from genetic interaction with Bx inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from mutant phenotype - "miR-9a, mir-9a, MIR-9, CR42891, miR-9, mir-9, CR33063, mir-9A, transfrag 22, dme-miR-9a, miR9a, dme-mir-9a, dme-miR-9a-5p" - CR42891 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0000218 brh brown head http://flybase.org/reports/FBgn0000218 - gene - - - brh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,denticle belt" FBgn0018737 Dns Dense http://flybase.org/reports/FBgn0018737 - gene - - - Dns - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,viable" macrochaeta FBgn0031296 CG4415 - http://flybase.org/reports/FBgn0031296 protein_coding_gene - - - CG4415 "IPR002715:Nascent polypeptide-associated complex NAC domain, IPR016641:Nascent polypeptide-associated complex subunit alpha" CG4415 11-Aug-17 DroID_v2017_08 "Drer\naca, Drer\nacad" Scer\EGD2 Cele\icd-2 "Xtro\naca.2, Xtro\naca" "Mmus\Nacad, Mmus\Naca" "Hsap\NACAD, Hsap\NACA2, Hsap\NACA" "female fertile,viable" FBgn0040025 CG12577 - http://flybase.org/reports/FBgn0040025 protein_coding_gene - - - CG12577 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031676 senju senju http://flybase.org/reports/FBgn0031676 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from electronic annotation with InterPro:IPR007271 UDP-galactose transmembrane transporter activity ; GO:0005459 | inferred from direct assay carbohydrate transport ; GO:0008643 | inferred from electronic annotation with InterPro:IPR007271 UDP-galactose transport ; GO:0015785 | inferred from direct assay negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007271 Golgi membrane ; GO:0000139 | inferred from electronic annotation with InterPro:IPR007271 Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi medial cisterna ; GO:0005797 | inferred from direct assay "senju, CG14040" IPR007271:Nucleotide-sugar transporter CG14040 11-Aug-17 DroID_v2017_08 "Drer\slc35a2, Drer\slc35a3a, Drer\slc35a5, Drer\slc35a1, Drer\slc35a3b, Drer\slc35a4" - Cele\nstp-5 "Xtro\slc35a5, Xtro\slc35a1, Xtro\slc35a3.2, Xtro\slc35a3.1" "Mmus\Slc35a1, Mmus\Slc35a3, Mmus\Slc35a5, Mmus\Slc35a4, Mmus\Slc35a2" "Hsap\SLC35A4, Hsap\SLC35A2, Hsap\SLC35A1, Hsap\SLC35A3, Hsap\SLC35A5" viable FBgn0264616 CR43956 - http://flybase.org/reports/FBgn0264616 non_protein_coding_gene - - - CR43956 - CR43956 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013395 anon-64Bc anon-64Bc http://flybase.org/reports/FBgn0013395 - gene - - - anon-64Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013520 l(1)rp3 lethal (1) rp3 http://flybase.org/reports/FBgn0013520 - gene - - - l(1)rp3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0082340 HM56 HM56 http://flybase.org/reports/FBgn0082340 gene - - - HM56 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005374 x4 x4 http://flybase.org/reports/FBgn0005374 - gene - - - x4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065923 l(2)SH0152 lethal (2) SH0152 http://flybase.org/reports/FBgn0065923 gene - - - l(2)SH0152 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027866 CG9776 - http://flybase.org/reports/FBgn0027866 FBan0009776 protein_coding_gene - - - "BcDNA:LD19168, CG9776" - CG9776 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-195b21.5, Drer\znf318" - "Cele\K08D8.4, Cele\D1044.6" - Mmus\Zfp318 Hsap\ZNF318 "viable,visible" trichogen cell FBgn0264712 CG1172 - http://flybase.org/reports/FBgn0264712 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from electronic annotation with InterPro:IPR032752 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG1172, CR43473, CC1172" "IPR032752:Ubiquitin-binding domain, IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG1172 11-Aug-17 DroID_v2017_08 "Drer\ubtd2, Drer\ubtd1a, Drer\ubtd1b" - - "Xtro\ubtd2, Xtro\ubtd1" "Mmus\Ubtd2, Mmus\Ubtd1" "Hsap\UBTD2, Hsap\UBTD1" FBgn0001724 l(1)ESHS45 lethal (1) ESHS45 http://flybase.org/reports/FBgn0001724 - gene - - - l(1)ESHS45 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000389 Cu-3 Curled 3 http://flybase.org/reports/FBgn0000389 - gene - - - "Cur, Cu-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" wing FBgn0052066 CG32066 - http://flybase.org/reports/FBgn0052066 protein_coding_gene - - perivitelline space ; GO:0098595 | inferred from direct assay "CG6491, CG6487, CG32066" "IPR009828:Protein of unknown function DUF1394, IPR011989:Armadillo-like helical" CG32066 11-Aug-17 DroID_v2017_08 "Drer\znf395, Drer\fam49bb, Drer\fam49ba, Drer\fam49a" - Cele\R07G3.8 "Xtro\fam49b, Xtro\fam49a, Xtro\LOC548655" "Mmus\Fam49a, Mmus\Fam49b" "Hsap\FAM49A, Hsap\FAM49B" "viable,fertile" FBgn0062604 Mod(var)1429 Mod(var)1429 http://flybase.org/reports/FBgn0062604 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1429, Mod(var)1429" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0013529 l(2)23AB7 lethal (2) 23AB7 http://flybase.org/reports/FBgn0013529 - gene - - - l(2)23AB7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033943 CG12869 - http://flybase.org/reports/FBgn0033943 protein_coding_gene neurexin family protein binding ; GO:0042043 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synapse assembly ; GO:0007416 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 CG12869 "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR029058:Alpha/Beta hydrolase fold" CG12869 11-Aug-17 DroID_v2017_08 "Drer\nlgn2b, Drer\si:ch211-93f2.1, Drer\nlgn2a, Drer\nlgn1, Drer\nlgn4a, Drer\nlgn3a, Drer\nlgn3b, Drer\cell, Drer\ces2, Drer\ces3, Drer\cel.1, Drer\nlgn4b" - "Cele\T22D1.11, Cele\W02B12.4, Cele\C23H4.4, Cele\ZC376.3, Cele\ZC376.1, Cele\ZC376.2, Cele\C17H12.4, Cele\T02B5.1, Cele\C01B10.10, Cele\glit-1, Cele\T07H6.1, Cele\ZK994.1, Cele\C23H4.7, Cele\T02B5.3, Cele\E01G6.3, Cele\C23H4.2, Cele\C23H4.3, Cele\C01B10.4, Cele\Y75B8A.3, Cele\nlg-1, Cele\C42D4.2" "Xtro\nlgn4x, Xtro\LOC100494782, Xtro\nlgn3, Xtro\cel, Xtro\nlgn2, Xtro\ces2, Xtro\ces3" "Mmus\Ces1h, Mmus\Ces1e, Mmus\Ces2g, Mmus\Nlgn1, Mmus\Ces2h, Mmus\Nlgn3, Mmus\Ces2b, Mmus\Ces3b, Mmus\Ces1d, Mmus\Ces1f, Mmus\Ces3a, Mmus\Ces1g, Mmus\Ces4a, Mmus\Ces2c, Mmus\Cel, Mmus\Ces1c, Mmus\Ces2a, Mmus\Ces2f, Mmus\Ces2e, Mmus\Nlgn2, Mmus\Ces5a, Mmus\Ces1b" "Hsap\CES3, Hsap\CES1, Hsap\CES4A, Hsap\CES5A, Hsap\NLGN1, Hsap\NLGN4X, Hsap\CES2, Hsap\NLGN4Y, Hsap\NLGN2, Hsap\CEL, Hsap\NLGN3" "viable,fertile" FBgn0266800 CR45262 - http://flybase.org/reports/FBgn0266800 non_protein_coding_gene - - - CR45262 - CR45262 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033340 CG13751 - http://flybase.org/reports/FBgn0033340 protein_coding_gene - - - "BcDNA:RH09719, CG13751" - CG13751 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033149 CG11060 - http://flybase.org/reports/FBgn0033149 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11060 "IPR032707:MYCBP-associated protein, IPR013783:Immunoglobulin-like fold" CG11060 11-Aug-17 DroID_v2017_08 Drer\mycbpap - - Xtro\mycbpap Mmus\Mycbpap Hsap\MYCBPAP viable FBgn0061071 l(3)S018310b lethal (3) S018310b http://flybase.org/reports/FBgn0061071 gene - - - "0183/10, l(3)S018310b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0001336 l(1)1Af lethal (1) 1Af http://flybase.org/reports/FBgn0001336 - gene - - - l(1)1Af - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0019940 Rh6 Rhodopsin 6 http://flybase.org/reports/FBgn0019940 - protein_coding_gene G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with ninaE inferred from sequence or structural similarity with Rh2 inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4 G-protein coupled photoreceptor activity ; GO:0008020 | inferred from genetic interaction with ninaE G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity G-protein coupled photoreceptor activity ; GO:0008020 | non-traceable author statement "visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR001760 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR001735, InterPro:IPR001760 entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from genetic interaction with Rh5, cry inferred from genetic interaction with Rh5, cry, norpA inferred from genetic interaction with cry, norpA sensory perception of sound ; GO:0007605 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from genetic interaction with ninaE phototransduction ; GO:0007602 | non-traceable author statement thermotaxis ; GO:0043052 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity phototransduction ; GO:0007602 | inferred from sequence or structural similarity with ninaE inferred from sequence or structural similarity with Rh2 inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR001735, InterPro:IPR001760, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity rhabdomere ; GO:0016028 | inferred from direct assay" "Rh6, rh6, Rh, RH6, DMELRH6, Dm Rh6, CG5192, R8" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001735:Opsin RH1/RH2, IPR001760:Opsin, IPR017452:GPCR, rhodopsin-like, 7TM, IPR027430:Visual pigments (opsins) retinal binding site" CG5192 11-Aug-17 DroID_v2017_08 "Drer\tmtops2a, Drer\opn4.1, Drer\valopb, Drer\opn1lw1, Drer\tmtops2b, Drer\opn4b, Drer\rrh, Drer\opn1sw2, Drer\opn8b, Drer\tmtopsb, Drer\opn1mw1, Drer\opn1sw1, Drer\opn4a, Drer\tmtops3a, Drer\opn7a, Drer\rho, Drer\opn5, Drer\valopa, Drer\rgrb, Drer\exorh, Drer\opn1mw3, Drer\opn7b, Drer\opn8c, Drer\opn4xa, Drer\opn9, Drer\opn6a, Drer\opn6b, Drer\parapinopsinb, Drer\opn4xb, Drer\rgra, Drer\opn7c, Drer\rhol, Drer\opn1lw2, Drer\opn3, Drer\opn1mw4, Drer\tmtops3b, Drer\opn7d, Drer\parietopsin" - "Cele\sro-1, Cele\nmur-3" "Xtro\opn1sw, Xtro\LOC100485989, Xtro\tmtops, Xtro\LOC100124934, Xtro\rho, Xtro\LOC100485437, Xtro\rrh, Xtro\tmtops.2, Xtro\opn1lw, Xtro\opn5" "Mmus\Rgr, Mmus\Rrh, Mmus\Opn3, Mmus\Rho, Mmus\Opn1mw, Mmus\Opn4, Mmus\Opn5, Mmus\Opn1sw" "Hsap\OPN1SW, Hsap\RRH, Hsap\OPN1LW, Hsap\OPN4, Hsap\OPN3, Hsap\RGR, Hsap\OPN1MW, Hsap\OPN1MW3, Hsap\RHO, Hsap\OPN5, Hsap\OPN1MW2" adult stage " adult head

, photoreceptor cell R8 | subset

" "auditory perception defective,neurophysiology defective,viable" FBgn0053092 P5CDh2 delta-1-Pyrroline-5-carboxylate dehydrogenase 2 http://flybase.org/reports/FBgn0053092 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016161, InterPro:IPR016162" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163" - "CG6670, P5CDh2, CG33092, DmP5CDh2" "IPR015590:Aldehyde dehydrogenase domain, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain" CG33092 11-Aug-17 DroID_v2017_08 "Drer\iffo2a, Drer\aldh4a1, Drer\zgc:162898" Scer\PUT2 Cele\alh-6 Xtro\aldh4a1 "Mmus\2300009A05Rik, Mmus\Aldh4a1, Mmus\Iffo2" "Hsap\IFFO2, Hsap\C15orf61, Hsap\ALDH4A1" FBgn0265630 sno strawberry notch http://flybase.org/reports/FBgn0265630 protein_coding_gene - imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype inferred from genetic interaction with H inferred from genetic interaction with Su(H) positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "sno, CG1903, CG44436, Sno, g-l, l(1)11Ea" "IPR026741:Protein strawberry notch, IPR026937:Strawberry notch, helicase C domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG44436 11-Aug-17 DroID_v2017_08 "Drer\sbno1, Drer\sbno2a, Drer\si:ch73-63e15.2" - Cele\let-765 "Xtro\sbno2, Xtro\sbno1" "Mmus\Sbno2, Mmus\Sbno1" "Hsap\SBNO2, Hsap\SBNO1" " larval stage , embryonic stage , adult stage && oogenesis stage , embryonic stage | stage 8 " " ventral thoracic disc | ubiquitous

, epidermis

, eye disc | ubiquitous

, embryonic central nervous system

, Malpighian tubule

, follicle cell

, dorsal mesothoracic disc | ubiquitous

, mesectoderm

, imaginal disc

" FBgn0084035 CG41475 - http://flybase.org/reports/FBgn0084035 protein_coding_gene - - - "CG41104, CG41103, CG41475" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266737 CR45210 - http://flybase.org/reports/FBgn0266737 non_protein_coding_gene - - - CR45210 - CR45210 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053116 CG33116 - http://flybase.org/reports/FBgn0053116 protein_coding_gene "phosphotransferase activity, for other substituted phosphate groups ; GO:0016780 | inferred from electronic annotation with InterPro:IPR000462" phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR000462 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000462 "CG10355, CG33116, dCCS1" "IPR000462:CDP-alcohol phosphatidyltransferase, IPR014472:Choline/ethanolamine phosphotransferase" CG33116 11-Aug-17 DroID_v2017_08 "Drer\chpt1, Drer\cept1a, Drer\si:ch211-197l9.4, Drer\cept1b" "Scer\CPT1, Scer\EPT1" "Cele\F54D7.2, Cele\cept-2, Cele\cept-1" "Xtro\chpt1, Xtro\cept1, Xtro\ept1" "Mmus\Chpt1, Mmus\Selenoi, Mmus\Cept1" "Hsap\CEPT1, Hsap\CHPT1, Hsap\SELENOI" "viable,visible" "chaeta,supernumerary" FBgn0062620 Mod(var)1181 Mod(var)1181 http://flybase.org/reports/FBgn0062620 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1181, Mod(var)1181" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced,suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0035227 Iml1 Increased minichromosome loss 1 http://flybase.org/reports/FBgn0035227 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with SGD:S000003899 GTPase activator activity ; GO:0005096 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000323637 negative regulation of TORC1 signaling ; GO:1904262 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from biological aspect of ancestor with PANTHER:PTN000323637 regulation of TORC1 signaling ; GO:1903432 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from biological aspect of ancestor with PANTHER:PTN000323637 regulation of autophagy ; GO:0010506 | inferred from biological aspect of ancestor with PANTHER:PTN000323637 cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype Seh1-associated complex ; GO:0035859 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN000995343 Iml1 complex ; GO:1990130 | traceable author statement Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000003899 "Iml1, CG12090, iml1, SEA1" IPR027244:Vacuolar membrane-associated protein Iml1 CG12090 11-Aug-17 DroID_v2017_08 Drer\depdc5 Scer\IML1 Cele\T08A11.1 Xtro\depdc5 Mmus\Depdc5 Hsap\DEPDC5 "viable,fertile" FBgn0065535 l(2)SH1089 lethal (2) SH1089 http://flybase.org/reports/FBgn0065535 gene - - - "l(2)SH1089, l(2)SH2 1089" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045060 fs(1)137a female sterile (1) 137a http://flybase.org/reports/FBgn0045060 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)137a - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "germarium,ovary" FBgn0020592 anon-57Ce anon-57Ce http://flybase.org/reports/FBgn0020592 - gene - - - anon-57Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001145 Gs2 Glutamine synthetase 2 http://flybase.org/reports/FBgn0001145 - protein_coding_gene glutamate-ammonia ligase activity ; GO:0004356 | inferred from direct assay glutamate-ammonia ligase activity ; GO:0004356 | non-traceable author statement glutamine biosynthetic process ; GO:0006542 | inferred from electronic annotation with InterPro:IPR008147 glutamine biosynthetic process ; GO:0006542 | non-traceable author statement glutamate catabolic process ; GO:0006538 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from mutant phenotype neurotransmitter receptor metabolic process ; GO:0045213 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:4341 "gs2, CG1743, GS2, gs-c, GsII, Gs2" "IPR008146:Glutamine synthetase, catalytic domain, IPR008147:Glutamine synthetase, beta-Grasp domain, IPR014746:Glutamine synthetase/guanido kinase, catalytic domain, IPR027302:Glutamine synthetase, N-terminal conserved site, IPR027303:Glutamine synthetase, glycine-rich site" CG1743 11-Aug-17 DroID_v2017_08 "Drer\glulb, Drer\glulc, Drer\glula, Drer\lgsn" Scer\GLN1 "Cele\gln-1, Cele\gln-5, Cele\gln-6, Cele\gln-2, Cele\gln-3" "Xtro\glul, Xtro\lgsn" "Mmus\Glul, Mmus\Lgsn" "Hsap\GLUL, Hsap\LGSN" " adult stage , larval stage | first instar , larval stage | second instar " "neurophysiology defective,viable" FBgn0265297 pAbp poly(A) binding protein http://flybase.org/reports/FBgn0265297 protein_coding_gene poly(A) binding ; GO:0008143 | traceable author statement poly(A) binding ; GO:0008143 | inferred from sequence or structural similarity with SGD:S000000967 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Paip2 poly(A) binding ; GO:0008143 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 "positive regulation of translation ; GO:0045727 | inferred from genetic interaction with grk regulation of compound eye photoreceptor development ; GO:0045314 | inferred from genetic interaction with pAbp male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype spermatid nucleus differentiation ; GO:0007289 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype negative regulation of neuron death ; GO:1901215 | inferred from genetic interaction with pAbp dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 male meiosis ; GO:0007140 | inferred from mutant phenotype" lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "PABP, pabp, pAbp, CG5119, Pabp, dPABP, pAB, PAbp, duo, l(2)k10109, anon-EST:Posey247, anon-EST:Posey249, BcDNA:LD24412, PABPC1, PABP55B, pABP, l(2)SH1908, l(2)SH2 1908, anon-EST:fe2E5, CG16803" "IPR000504:RNA recognition motif domain, IPR002004:Polyadenylate-binding protein/Hyperplastic disc protein, IPR006515:Polyadenylate binding protein, human types 1, 2, 3, 4" CG5119 11-Aug-17 DroID_v2017_08 "Drer\pabpc1b, Drer\pabpc1l, Drer\LOC100537585, Drer\pabpc1a, Drer\pabpc4, Drer\ncl, Drer\zgc:171310" "Scer\MIP6, Scer\PES4, Scer\PAB1" "Cele\pab-2, Cele\pab-1" "Xtro\pabpc1l, Xtro\pabpc1, Xtro\pabpc4" "Mmus\Pabpc6, Mmus\Pabpc4l, Mmus\Pabpc2, Mmus\Pabpc5, Mmus\Pabpc1l, Mmus\Pabpc1, Mmus\Pabpc4" "Hsap\PABPC1L2B, Hsap\PABPC4, Hsap\PABPC3, Hsap\PABPC4L, Hsap\PABPC1, Hsap\PABPC5, Hsap\PABPC1L2A, Hsap\PABPC1L" " oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

DRSC07659 IEK 1.096973612 -6.200961709 -2.273655693 -3.389501586 3.14274607 2.47206588 FBgn0030841 CG8568 - http://flybase.org/reports/FBgn0030841 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8568 IPR031941:Domain of unknown function DUF4773 CG8568 11-Aug-17 DroID_v2017_08 - - Cele\C09D4.2 Xtro\LOC100498624 "Mmus\Hrc, Mmus\Akap5" - "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0265316 CR44289 - http://flybase.org/reports/FBgn0265316 non_protein_coding_gene - - - "CR44289, lincRNA.872" - CR44289 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002174 l(2)tid lethal (2) tumorous imaginal discs http://flybase.org/reports/FBgn0002174 FBgn0034896 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012724 unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001305, InterPro:IPR008971, InterPro:IPR012724 heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001305 patched binding ; GO:0005113 | inferred from physical interaction with ptc" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971, InterPro:IPR012724 response to heat ; GO:0009408 | inferred from electronic annotation with InterPro:IPR012724 smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with ptc inferred from physical interaction with ptc sleep ; GO:0030431 | inferred from expression pattern mitochondrion organization ; GO:0007005 | inferred from biological aspect of ancestor with PANTHER:PTN001180543" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "lethal (2) tumorous imaginal discs, l(2)tumorous imaginal discs, TID56, DnaJ, tid, cDNA 10D, l(2)tumorous disc, l(2)tud, l(2)td, l(2)701, CG5504, l(2)tid" "IPR018253:DnaJ domain, conserved site, IPR001305:Heat shock protein DnaJ, cysteine-rich domain, IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR012724:Chaperone DnaJ" CG5504 11-Aug-17 DroID_v2017_08 "Drer\dnaja3a, Drer\dnaja3b, Drer\LOC554962, Drer\dnajc16, Drer\dnajc16l, Drer\dnajc24" "Scer\ERJ5, Scer\APJ1, Scer\JJJ1, Scer\MDJ1, Scer\SCJ1" Cele\dnj-10 "Xtro\dnajc24, Xtro\dnajc16, Xtro\dnaja3" "Mmus\Dnaja3, Mmus\Dnajc16, Mmus\Dnajc24" "Hsap\DNAJC16, Hsap\DNAJA3, Hsap\DNAJC24" " larval stage , adult stage , embryonic stage -- adult stage " "wild-type,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,tumorigenic" "wing disc,imaginal disc" FBgn0058384 CG40384 - http://flybase.org/reports/FBgn0058384 protein_coding_gene - - - CG40384 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264081 CG43750 - http://flybase.org/reports/FBgn0264081 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43750 - CG43750 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040547 CG14706 - http://flybase.org/reports/FBgn0040547 protein_coding_gene - - - CG14706 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060966 l(3)S030901b lethal (3) S030901b http://flybase.org/reports/FBgn0060966 gene - - - "0309/01, l(3)S030901b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030913 CG6123 - http://flybase.org/reports/FBgn0030913 protein_coding_gene - - - CG6123 - CG6123 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC30011 K 0.444283181 0.274089522 -0.061174379 0.575082419 1.316855014 1.906566258 FBgn0267015 CR45459 - http://flybase.org/reports/FBgn0267015 non_protein_coding_gene - - - CR45459 - CR45459 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000318 cl clot http://flybase.org/reports/FBgn0000318 "FBgn0031709, FBgn0063070" protein_coding_gene protein-disulfide reductase activity ; GO:0047134 | inferred from biological aspect of ancestor with PANTHER:PTN000278790 eye pigment biosynthetic process ; GO:0006726 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000278790 "CG11024, BcDNA:RE06767, cl" "IPR010357:Protein of unknown function DUF953, thioredoxin-like, IPR012336:Thioredoxin-like fold" CG11024 11-Aug-17 DroID_v2017_08 Drer\txndc17 - Cele\Y71H2AR.1 Xtro\txndc17 Mmus\Txndc17 Hsap\TXNDC17 "viable,fertile,eye color defective" "Malpighian tubule,pigment cell" FBgn0267920 CR46201 - http://flybase.org/reports/FBgn0267920 non_protein_coding_gene - - - "CR46201, lincRNA.919" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262118 l(2)NC173 - http://flybase.org/reports/FBgn0262118 gene - - - l(2)NC173 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031281 Saf6 SAGA factor-like TAF6 http://flybase.org/reports/FBgn0031281 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with e(y)1 inferred from physical interaction with e(y)1 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay SAGA-type complex ; GO:0070461 | inferred from direct assay "SAF6, saf6, Saf6, CG3883" - CG3883 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC00633 E -0.149480242 0.362396254 -0.241661292 1.692060646 -0.448121921 0.217145176 FBgn0023433 l(2)4-3A lethal (2) 4-3A http://flybase.org/reports/FBgn0023433 - gene - - - l(2)4-3A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019845 anon-XXIII anon-XXIII http://flybase.org/reports/FBgn0019845 - gene - - - "XXIII, anon-XXIII" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005284 M(3)S36 Minute (3) 36 http://flybase.org/reports/FBgn0005284 - gene - - - "M(3)s36, M(3)S36" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible" macrochaeta FBgn0069447 E(br)333 E(br)333 http://flybase.org/reports/FBgn0069447 gene - - - E(br)333 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,semidominant" leg FBgn0044411 Scim16 Sensitized chromosome inheritance modifier 16 http://flybase.org/reports/FBgn0044411 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0011195 l(1)302-9 lethal (1) 302-9 http://flybase.org/reports/FBgn0011195 FBgn0010202 gene - - - "302-9, l(1)302-9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053964 CG33964 - http://flybase.org/reports/FBgn0053964 protein_coding_gene - - - "CG8447, CG33154, CG13174, CG33964, CT32415" "IPR025714:Methyltransferase domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG33964 11-Aug-17 DroID_v2017_08 "Drer\mettl25, Drer\orc3, Drer\rrnad1" - Cele\F25H2.12 "Xtro\rrnad1, Xtro\orc3, Xtro\mettl25" "Mmus\Mettl25, Mmus\Rrnad1, Mmus\Orc3" "Hsap\ORC3, Hsap\RRNAD1, Hsap\METTL25" FBgn0046123 E(To)12 E(To)12 http://flybase.org/reports/FBgn0046123 gene - - - E(To)12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037638 CG8379 - http://flybase.org/reports/FBgn0037638 protein_coding_gene - - - "anon-WO0118547.250, CG8379" "IPR013636:Domain of unknown function DUF1741, IPR011989:Armadillo-like helical" CG8379 11-Aug-17 DroID_v2017_08 Drer\zgc:63733 - - Xtro\c10orf76 Mmus\9130011E15Rik Hsap\C10orf76 "viable,fertile" FBgn0267432 kl-3 male fertility factor kl3 http://flybase.org/reports/FBgn0267432 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity with CG9492 traceable author statement ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q8TE73 axonemal dynein complex ; GO:0005858 | inferred from sequence or structural similarity axonemal dynein complex ; GO:0005858 | inferred from mutant phenotype "CG17629, kl3, kl-3, CG45785, CG40992, CG40936, kl-4, Y104b, Lms3, CG40443, ms(Y)104b, DHC4A" "IPR026983:Dynein heavy chain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013594:Dynein heavy chain, domain-1, IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013602:Dynein heavy chain, domain-2, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk" CG45785 11-Aug-17 DroID_v2017_08 "Drer\dnah5, Drer\si:dkeyp-87a6.1" - - - "Mmus\Dnah5, Mmus\Dnah8" "Hsap\DNAH5, Hsap\DNAH8" FBgn0264277 Su(Mir)3 - http://flybase.org/reports/FBgn0264277 gene - - - Su(Mir)3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0062572 Mod(var)E1350 Mod(var)E1350 http://flybase.org/reports/FBgn0062572 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1350, Mod(var)E1350" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0041827 ISO-Q ISO-Q http://flybase.org/reports/FBgn0041827 gene - - - ISO-Q - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" FBgn0028146 l(3)S045507b lethal (3) S045507b http://flybase.org/reports/FBgn0028146 gene - - - "0455/07, l(3)S045507, l(3)S045507b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053404 5SrRNA:CR33404 5SrRNA:CR33404 http://flybase.org/reports/FBgn0053404 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33404, 5SrRNA:CR33404" - CR33404 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083278 E(smoDN)2515 Enhancer of smoDN 2515 http://flybase.org/reports/FBgn0083278 gene - - - E(smoDN)2515 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267005 CR45449 - http://flybase.org/reports/FBgn0267005 non_protein_coding_gene - - - "CR45449, R5_2L:3854289..3854886" - CR45449 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065750 l(2)SH0498 lethal (2) SH0498 http://flybase.org/reports/FBgn0065750 gene - - - "l(2)SH0498, l(2)SH2 0498" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027142 l(3)71EFa lethal (3) 71EFa http://flybase.org/reports/FBgn0027142 - gene - - - l(3)71EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0031896 CG4502 - http://flybase.org/reports/FBgn0031896 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.403, CG4502" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG4502 11-Aug-17 DroID_v2017_08 "Drer\ube2q2, Drer\ube2ql1, Drer\ube2q1" Scer\CDC34 Cele\ubc-25 "Xtro\ube2q2, Xtro\ube2ql1" "Mmus\Ube2q1, Mmus\Ube2ql1, Mmus\Ube2q2" "Hsap\UBE2QL1, Hsap\UBE2Q2, Hsap\UBE2Q1" "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0267956 CR46236 - http://flybase.org/reports/FBgn0267956 non_protein_coding_gene - - - "CR46236, lincRNA.901" - CR46236 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262395 mir-12 mir-12 stem loop http://flybase.org/reports/FBgn0262395 miRNA_gene - "gene silencing by miRNA ; GO:0035195 | inferred from direct assay positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from genetic interaction with Ge-1, me31B positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype" - "dme-mir-12, mir-12, miR-12, MIR-12, CR42932, miR12, Mir-12, CR33076, pri-miR-12, MiR-12, dme-miR-12, dme-miR-12-3p, miR-12/283/304" - CR42932 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage "visible,lethal,lethal - all die before end of larval stage,some die during larval stage" "wing,wing vein,wing margin" FBgn0069233 gl(2L)179-26 gl(2L)179-26 http://flybase.org/reports/FBgn0069233 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(2L)179-26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "egg,germline clone,maternal effect,dorsal appendage,cephalopharyngeal skeleton" FBgn0040824 CG14169 - http://flybase.org/reports/FBgn0040824 protein_coding_gene - - - CG14169 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033566 CG18004 - http://flybase.org/reports/FBgn0033566 protein_coding_gene - DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR026678 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR026678 Ino80 complex ; GO:0031011 | inferred from biological aspect of ancestor with PANTHER:PTN001094779 CG18004 IPR026678:INO80 complex subunit E CG18004 11-Aug-17 DroID_v2017_08 Drer\ino80e - - - Mmus\Ino80e Hsap\INO80E FBgn0037655 Kcmf1 Potassium channel modulatory factor 1 http://flybase.org/reports/FBgn0037655 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 - - "CG11984, KCMF1, Kcmf1" "IPR000433:Zinc finger, ZZ-type, IPR008598:Drought induced 19 protein type, zinc-binding domain" CG11984 11-Aug-17 DroID_v2017_08 Drer\kcmf1 - "Cele\trf-1, Cele\ZK652.6" Xtro\kcmf1 Mmus\Kcmf1 Hsap\KCMF1 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0017461 TfIIIB Transcription factor IIIB http://flybase.org/reports/FBgn0017461 - gene - transcription from RNA polymerase III promoter ; GO:0006383 | traceable author statement - "TFIIIB, IIIB, TfIIIB" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001642 l(1)dn22 lethal (1) discs normal 22 http://flybase.org/reports/FBgn0001642 - gene - - - "l(1)d.norm.-22, l(1)dn22" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0085287 CG34258 - http://flybase.org/reports/FBgn0085287 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34258 - CG34258 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015337 anon-23EFa anon-23EFa http://flybase.org/reports/FBgn0015337 - gene - - - anon-23EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004578 l(3)hem lethal (3) hematopoiesis missing http://flybase.org/reports/FBgn0004578 - gene - - - "l(3)hem, l-(3)hem" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cytokinesis defective,recessive,lethal - all die before end of larval stage,some die during larval stage" "prohemocyte,plasmatocyte,crystal cell,embryonic/larval lymph gland,embryonic/larval optic lobe,neuroblast" FBgn0028093 l(3)S078514 lethal (3) S078514 http://flybase.org/reports/FBgn0028093 gene - - - "0785/14, l(3)S078514" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084050 CR41470 - http://flybase.org/reports/FBgn0084050 non_protein_coding_gene - - - CR41470 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017436 anon-28Cc anon-28Cc http://flybase.org/reports/FBgn0017436 - gene - - - anon-28Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035550 CG11349 - http://flybase.org/reports/FBgn0035550 protein_coding_gene - - - CG11349 - CG11349 11-Aug-17 DroID_v2017_08 "Drer\col1a1b, Drer\col9a2, Drer\col11a1a, Drer\col11a1b, Drer\col7a1l, Drer\wu:fc38h03, Drer\col2a1a, Drer\col17a1b, Drer\col1a2, Drer\col12a1b, Drer\si:ch211-196i2.1, Drer\LOC101883924, Drer\col4a6, Drer\col28a1a, Drer\col5a1, Drer\col6a1, Drer\col27a1b, Drer\col9a1a, Drer\col16a1, Drer\col4a2, Drer\col4a5, Drer\zgc:153049, Drer\col1a1a, Drer\si:ch211-106n13.3, Drer\col5a2b, Drer\col2a1b, Drer\col14a1a, Drer\col11a2, Drer\si:dkey-225n22.4, Drer\col6a2, Drer\col6a3, Drer\col27a1a, Drer\LOC101884357, Drer\col6a4a, Drer\LOC100538221, Drer\si:dkey-61l1.4, Drer\col5a2a, Drer\col9a1b" - - "Xtro\col11a2, Xtro\col1a1, Xtro\col2a1, Xtro\col6a2, Xtro\col24a1, Xtro\col5a1, Xtro\col4a1, Xtro\col1a2, Xtro\LOC100486063, Xtro\col27a1, Xtro\col14a1, Xtro\col4a5, Xtro\col3a1, Xtro\col4a6, Xtro\col4a2, Xtro\col7a1" "Mmus\Col6a6, Mmus\Col11a1, Mmus\Col6a1, Mmus\Col4a2, Mmus\Col1a2, Mmus\Col3a1, Mmus\Col2a1, Mmus\Col6a3, Mmus\Tnn, Mmus\Col6a5, Mmus\Col5a3, Mmus\Col4a1, Mmus\Col4a4, Mmus\Col4a3, Mmus\Col1a1, Mmus\Col17a1, Mmus\Col11a2, Mmus\Col9a1, Mmus\Col5a2, Mmus\Col28a1, Mmus\Col16a1, Mmus\Col7a1, Mmus\Col9a3, Mmus\Col4a6, Mmus\Col6a4, Mmus\Col20a1, Mmus\Col23a1, Mmus\Col19a1, Mmus\8030474K03Rik, Mmus\Col13a1, Mmus\Col22a1, Mmus\Vwa1, Mmus\Col5a1, Mmus\Col4a5, Mmus\Col27a1, Mmus\Col24a1, Mmus\4933412E24Rik, Mmus\Col14a1, Mmus\Vwa2, Mmus\Col25a1" "Hsap\COL2A1, Hsap\COL4A2, Hsap\COL20A1, Hsap\COL11A1, Hsap\COL1A1, Hsap\COL4A6, Hsap\COL9A3, Hsap\VWA1, Hsap\COL1A2, Hsap\VWA2, Hsap\COL6A1, Hsap\COL4A4, Hsap\COL9A2, Hsap\COL16A1, Hsap\COL11A2, Hsap\COL6A3, Hsap\COL14A1, Hsap\COL17A1, Hsap\COL23A1, Hsap\COL4A5, Hsap\COL4A3, Hsap\COL5A2, Hsap\COL19A1, Hsap\COL4A1, Hsap\COL6A6, Hsap\COL27A1, Hsap\COL25A1, Hsap\COL5A3, Hsap\COL5A1, Hsap\COL7A1, Hsap\COLQ, Hsap\COL24A1, Hsap\COL3A1, Hsap\COL6A5, Hsap\COL9A1, Hsap\COL22A1" "viable,visible" trichogen cell FBgn0004081 XDm XDm element http://flybase.org/reports/FBgn0004081 - repeat_region - - - XDm - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024720 Su(var)99C99E Su(var)99C99E http://flybase.org/reports/FBgn0024720 - gene - - - Su(var)99C99E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003583 Su(stn) Suppressor of stoned http://flybase.org/reports/FBgn0003583 - gene - - - Su(stn) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020616 SA Stromalin http://flybase.org/reports/FBgn0020616 FBgn0020933 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with SGD:S000001288 synaptonemal complex assembly ; GO:0007130 | inferred from mutant phenotype mitotic sister chromatid cohesion ; GO:0007064 | inferred from sequence or structural similarity with SGD:S000001288 neuron remodeling ; GO:0016322 | inferred from mutant phenotype "spindle pole ; GO:0000922 | inferred from direct assay cohesin complex ; GO:0008278 | non-traceable author statement condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay pericentric heterochromatin ; GO:0005721 | inferred from direct assay cohesin complex ; GO:0008278 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay nuclear mitotic cohesin complex ; GO:0034990 | inferred from sequence or structural similarity with SGD:S000001288" "DmSA, SCC3, DSA, ESTS:92H2T, CG3423, SA, Scc3, DSA1" "IPR013721:STAG, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR020839:Stromalin conservative domain" CG3423 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-269e2.1, Drer\stag2a, Drer\stag1b, Drer\stag2b, Drer\stag1a" Scer\IRR1 Cele\scc-3 "Xtro\stag1, Xtro\stag3" "Mmus\Stag2, Mmus\Stag3, Mmus\Stag1" "Hsap\STAG3, Hsap\STAG1, Hsap\STAG2" "lethal - all die before end of pupal stage,partially,some die during pupal stage,planar polarity defective" DRSC03424 K -0.223030754 0.870827593 0.051109107 1.44912264 1.790112427 2.615684226 FBgn0029672 CG2875 - http://flybase.org/reports/FBgn0029672 protein_coding_gene - "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000278911 neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000278911 Noc4p-Nop14p complex ; GO:0030692 | inferred from biological aspect of ancestor with PANTHER:PTN000278911 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000278911 CG2875 "IPR005612:CCAAT-binding factor, IPR027193:Nucleolar complex protein 4, IPR011989:Armadillo-like helical" CG2875 11-Aug-17 DroID_v2017_08 Drer\noc4l Scer\NOC4 Cele\T20B12.3 Xtro\noc4l Mmus\Noc4l Hsap\NOC4L "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0053170 CG33170 - http://flybase.org/reports/FBgn0053170 protein_coding_gene - - - "CG8244, BcDNA:AT30788, CG33170" IPR027854:Protein of unknown function DUF4535 CG33170 11-Aug-17 DroID_v2017_08 - - Cele\B0205.12 - - Hsap\C7orf73 viable FBgn0027998 l(3)S122404 lethal (3) S122404 http://flybase.org/reports/FBgn0027998 gene - - - "1224/04, l(3)S122404" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083990 sphinx sphinx http://flybase.org/reports/FBgn0083990 non_protein_coding_gene - male courtship behavior ; GO:0008049 | inferred from mutant phenotype - "sphinx, CR34154, spx, Sphinx" - CR34154 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,male limited" FBgn0001347 l(1)1Eb lethal (1) 1Eb http://flybase.org/reports/FBgn0001347 - gene - - - "HM-14, l(1)1Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,recessive,lethal" FBgn0266156 CR44862 - http://flybase.org/reports/FBgn0266156 non_protein_coding_gene - - - CR44862 - CR44862 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034168 CG15614 - http://flybase.org/reports/FBgn0034168 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452" CG15614 "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG15614 11-Aug-17 DroID_v2017_08 - - "Cele\T10E10.3, Cele\K03H6.5, Cele\srw-65, Cele\D1014.2, Cele\R13H7.2, Cele\F40A3.7, Cele\B0563.6, Cele\glb-33, Cele\W10C4.1, Cele\F59B2.13, Cele\K03H6.1" - - - viable FBgn0032865 CG15477 - http://flybase.org/reports/FBgn0032865 protein_coding_gene - - - CG15477 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0058271 CG40271 - http://flybase.org/reports/FBgn0058271 protein_coding_gene - - - CG40271 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044338 297\gag 297 element gag http://flybase.org/reports/FBgn0044338 transposable_element_gene - - - "297\gag, gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029697 CG15570 - http://flybase.org/reports/FBgn0029697 protein_coding_gene - - chorion ; GO:0042600 | inferred from direct assay CG15570 - CG15570 11-Aug-17 DroID_v2017_08 - - Cele\ssq-4 - - - viable FBgn0039999 CG17787 - http://flybase.org/reports/FBgn0039999 protein_coding_gene - - - "CG40398, CG17787" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050391 CG30391 - http://flybase.org/reports/FBgn0050391 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15662, CG30391" - CG30391 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015434 l(1)4Da lethal (1) 4Da http://flybase.org/reports/FBgn0015434 - gene - - - l(1)4Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0066130 E(sda)C E(sda)C http://flybase.org/reports/FBgn0066130 gene - - - "E(sda)C, Line C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039969 Fis1 "Fission, mitochondrial 1" http://flybase.org/reports/FBgn0039969 protein_coding_gene - positive regulation of mitochondrial fission ; GO:0090141 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from genetic interaction with Pink1 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:21689 "bs15a08.y1, BcDNA:RE29957, NEST:bs15a08, dFis1, Fis1, CG17510, fis1" "IPR011990:Tetratricopeptide-like helical domain, IPR033745:Mitochondria fission protein Fis1, cytosolic domain, IPR028061:Fis1, C-terminal tetratricopeptide repeat, IPR028058:Fis1, N-terminal tetratricopeptide repeat, IPR016543:Mitochondria fission 1 protein" CG17510 11-Aug-17 DroID_v2017_08 Drer\fis1 Scer\FIS1 "Cele\fis-1, Cele\fis-2" Xtro\fis1 Mmus\Fis1 Hsap\FIS1 FBgn0010883 l(3)06240 lethal (3) 06240 http://flybase.org/reports/FBgn0010883 - gene - - - l(3)06240 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039034 Or94b Odorant receptor 94b http://flybase.org/reports/FBgn0039034 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "94b, DOR109, 94D.2, anon-JP2002534971-A.32, anon-JP2002534971-A.31, CG6679, Or94b" "IPR004117:Olfactory receptor, insect" CG6679 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0022160 Gpo-1 Glycerophosphate oxidase-1 http://flybase.org/reports/FBgn0022160 "FBgn0034048, FBgn0042124, FBgn0062235, FBgn0001129" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from mutant phenotype glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from sequence or structural similarity with UniProtKB:P43304 glycerol-3-phosphate metabolic process ; GO:0006072 | inferred from electronic annotation with InterPro:IPR000447 glycerol metabolic process ; GO:0006071 | inferred from sequence or structural similarity with UniProtKB:P43304 flight behavior ; GO:0007629 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype glycerophosphate shuttle ; GO:0006127 | inferred from mutant phenotype "glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR000447 mitochondrial inner membrane ; GO:0005743 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P43304 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred by curator from GO:0004368,GO:0006127 mitochondrion ; GO:0005739 | inferred from direct assay" "l(2)k05713, CG8256, CG18786, anon-WO0118547.114, Gpo-1, alpha-GPO, alphaGPO, Gpo, GPO, GPO-1, CG 8256, 1(2) K05713" "IPR018247:EF-Hand 1, calcium-binding site, IPR000447:FAD-dependent glycerol-3-phosphate dehydrogenase, IPR002048:EF-hand domain, IPR006076:FAD dependent oxidoreductase, IPR011992:EF-hand domain pair, IPR031656:Alpha-glycerophosphate oxidase, C-terminal, IPR023753:FAD/NAD(P)-binding domain" CG8256 11-Aug-17 DroID_v2017_08 Drer\gpd2 Scer\GUT2 "Cele\T25G3.4, Cele\Y50E8A.6" Xtro\gpd2 Mmus\Gpd2 Hsap\GPD2 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,recessive,viable,flightless" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0250910 Octbeta3R Octopamine beta3 receptor http://flybase.org/reports/FBgn0250910 protein_coding_gene octopamine receptor activity ; GO:0004989 | inferred from sequence or structural similarity with UniProtKB:Q9VCZ3 inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity adenylate cyclase-activating G-protein coupled receptor signaling pathway ; GO:0007189 | inferred from sequence or structural similarity with UniProtKB:Q9VCZ3 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010579 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "Octbeta3R, CG7078, DmOctbeta3R, CG33959, DmCG7078, CG31350, CG31351, CG31348, OctBeta3, CG18554, anon-WO0170980.188, anon-WO0170980.187, CG34055, CG42244, octRbeta3, Octb3R, octbeta3R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG42244 11-Aug-17 DroID_v2017_08 "Drer\taar12e, Drer\taar14b, Drer\taar10c, Drer\si:ch211-139n6.11, Drer\taar14e, Drer\taar20j, Drer\taar12h, Drer\taar20b, Drer\taar13c, Drer\taar19o, Drer\taar13b, Drer\taar20q, Drer\taar19c, Drer\taar19p, Drer\taar20u, Drer\taar14g, Drer\taar12f, Drer\taar20x, Drer\taar12i, Drer\taar15, Drer\taar14i, Drer\taar20n, Drer\taar18e, Drer\taar20r, Drer\si:dkey-246e3.4, Drer\taar13d, Drer\taar20a, Drer\taar12a, Drer\taar10a, Drer\taar10d, Drer\taar1b, Drer\taar10, Drer\taar12g, Drer\taar19e, Drer\taar11, Drer\taar20o, Drer\taar14l, Drer\taar18g, Drer\taar12j, Drer\taar14j, Drer\taar19k, Drer\zgc:153137, Drer\taar14f, Drer\taar20c1, Drer\taar18c, Drer\taar19r, Drer\taar14h, Drer\taar20c, Drer\taar13e, Drer\taar20h, Drer\taar14a, Drer\LOC100149223, Drer\htr4, Drer\taar12c, Drer\taar20w, Drer\taar20i, Drer\taar19b, Drer\taar64, Drer\taar18a, Drer\taar12b, Drer\taar14d, Drer\taar20l, Drer\taar12m, Drer\taar10b, Drer\si:ch211-238p8.35, Drer\taar16f, Drer\taar19d, Drer\hrh2a, Drer\taar19m, Drer\taar19g, Drer\taar18b, Drer\hrh2b, Drer\taar20t, Drer\si:dkey-247m21.3" - "Cele\npr-1, Cele\F59D12.1, Cele\ser-5, Cele\C01F1.4" "Xtro\htr4, Xtro\hrh2" "Mmus\Taar7e, Mmus\Htr4, Mmus\Hrh2, Mmus\Taar7a, Mmus\Taar6, Mmus\Taar7f, Mmus\Taar7d, Mmus\Taar9, Mmus\Taar2, Mmus\Taar1, Mmus\Taar8a, Mmus\Taar8b, Mmus\Taar7b, Mmus\Taar5, Mmus\Taar8c, Mmus\Taar4, Mmus\Taar3" "Hsap\TAAR8, Hsap\HTR4, Hsap\TAAR6, Hsap\TAAR9, Hsap\TAAR1, Hsap\TAAR2, Hsap\TAAR5, Hsap\HRH2" """DRSC15351, DRSC24019"" " IEK FBgn0066126 E(sda)H E(sda)H http://flybase.org/reports/FBgn0066126 gene - - - "E(sda)H, Line H" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036560 CG5895 - http://flybase.org/reports/FBgn0036560 protein_coding_gene phosphoric diester hydrolase activity ; GO:0008081 | inferred from electronic annotation with InterPro:IPR017946 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR017946 - CG5895 "IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain" CG5895 11-Aug-17 DroID_v2017_08 "Drer\plcxd1, Drer\LOC100151335, Drer\zgc:112023, Drer\zgc:64065, Drer\si:dkey-66a8.7, Drer\plcxd2, Drer\plcxd3" - Cele\F38E9.1 "Xtro\plcxd3, Xtro\plcxd2, Xtro\plcxd1" "Mmus\Plcxd1, Mmus\Plcxd2, Mmus\Plcxd3" "Hsap\PLCXD1, Hsap\PLCXD2, Hsap\PLCXD3" "viable,fertile" FBgn0084022 CG41461 - http://flybase.org/reports/FBgn0084022 protein_coding_gene - - - CG41461 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052104 CG32104 - http://flybase.org/reports/FBgn0052104 protein_coding_gene molecular_function ; GO:0003674 | no biological data available transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with SGD:S000002935 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000486254 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002935 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000486254 "CG14124, anon-69Ag, CG14123, CG32104" "IPR016024:Armadillo-type fold, IPR013929:RNA polymerase II-associated protein 1, C-terminal, IPR013930:RNA polymerase II-associated protein 1, N-terminal, IPR011989:Armadillo-like helical" CG32104 11-Aug-17 DroID_v2017_08 Drer\rpap1 Scer\RBA50 Cele\F56B3.4 Xtro\rpap1 Mmus\Rpap1 Hsap\RPAP1 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0065963 l(2)SH0026 lethal (2) SH0026 http://flybase.org/reports/FBgn0065963 gene - - - "l(2)SH0026, l(2)SH2 0026" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032065 CG12438 - http://flybase.org/reports/FBgn0032065 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12438 - CG12438 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025115 Acyp Acylphosphatase http://flybase.org/reports/FBgn0025115 - protein_coding_gene acylphosphatase activity ; GO:0003998 | inferred from direct assay acylphosphatase activity ; GO:0003998 | inferred from sequence or structural similarity - - "AcPDro, CG16870, ACPDro, BG:DS00180.1, Acyp" "IPR001792:Acylphosphatase-like domain, IPR017968:Acylphosphatase, conserved site, IPR020456:Acylphosphatase" CG16870 11-Aug-17 DroID_v2017_08 "Drer\acyp2, Drer\acyp1" - - "Xtro\acyp1, Xtro\acyp2" "Mmus\Acyp2, Mmus\Acyp1" "Hsap\ACYP1, Hsap\ACYP2" FBgn0265397 EP2124 - http://flybase.org/reports/FBgn0265397 gene - - - EP2124 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005702 l(1)TK105 lethal (1) TK105 http://flybase.org/reports/FBgn0005702 - gene - - - "l105, l(1)TK105" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina,optic lobe" FBgn0065165 l(3)SH034 lethal (3) SH034 http://flybase.org/reports/FBgn0065165 gene - - - "l(3)SH034, l(2)SH3 034" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263517 mir-4976 mir-4976 stem loop http://flybase.org/reports/FBgn0263517 miRNA_gene - - - "mir-4976, CR43502, dme-mir-4976" - CR43502 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0042681 Rt1b\RTase Rt1b element RTase http://flybase.org/reports/FBgn0042681 transposable_element_gene - - - "ORF2, Waldo-A\RTase, Rt1b\RTase" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002175 l(3)5G83 lethal (3) 5G83 http://flybase.org/reports/FBgn0002175 - gene - - - l(3)5G83 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal dorsal closure embryo FBgn0267003 CR45447 - http://flybase.org/reports/FBgn0267003 non_protein_coding_gene - - - CR45447 - CR45447 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000200 bly bellyache http://flybase.org/reports/FBgn0000200 - gene molecular_function ; GO:0003674 | no biological data available Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bly - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic Malpighian tubule,embryonic/larval midgut" FBgn0262815 CR43186 - http://flybase.org/reports/FBgn0262815 pseudogene_attribute - - - "CG43186, CR43186, DMG6-MB6.chr2R.20.008" - CR43186 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005117 l(1)FMa lethal (1) FMa http://flybase.org/reports/FBgn0005117 - gene - - - "l(1)69a, l(1)FMa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086373 EP3916 - http://flybase.org/reports/FBgn0086373 gene - - - EP3916 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028841 jhamt juvenile hormone acid methyltransferase http://flybase.org/reports/FBgn0028841 protein_coding_gene juvenile hormone acid methyltransferase activity ; GO:0035049 | inferred from direct assay farnesoic acid O-methyltransferase activity ; GO:0019010 | inferred from direct assay juvenile hormone biosynthetic process ; GO:0006718 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype juvenile hormone biosynthetic process ; GO:0006718 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000010478 "CG17330, DmJHAMT, BG:DS09218.5, JAHMT, jhamt, JHAMT, JHamt, Jhamt" "IPR013217:Methyltransferase type 12, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG17330 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,viable" male genitalia FBgn0004209 l(3)84Eg lethal (3) 84Eg http://flybase.org/reports/FBgn0004209 - gene - - - l(3)84Eg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002801 ms(1)19E male sterile (1) 19E http://flybase.org/reports/FBgn0002801 - gene - - - "ms(1)E, ms(1)19E" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0260611 2L1794 - http://flybase.org/reports/FBgn0260611 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1794 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0041594 l(3)10 lethal (3) 10 http://flybase.org/reports/FBgn0041594 gene - - - l(3)10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062681 EP1595 EP1595 http://flybase.org/reports/FBgn0062681 gene - - - "EP(X)1595, EP1595" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" eye FBgn0284249 Adf1 Adh transcription factor 1 http://flybase.org/reports/FBgn0284249 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" "positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement locomotion ; GO:0040011 | inferred from mutant phenotype regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay memory ; GO:0007613 | inferred from mutant phenotype olfactory learning ; GO:0008355 | non-traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype long-term memory ; GO:0007616 | traceable author statement learning or memory ; GO:0007611 | non-traceable author statement larval locomotory behavior ; GO:0008345 | non-traceable author statement" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity polytene chromosome interband ; GO:0005705 | inferred from direct assay "l(2)k14805, Adf1, ADF1, Adf-1, Adh transcription factor 1, nal, CG15845, Adf 1, adf1, l(2)01349, l(2)04065, adf-1" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR004210:BESS motif, IPR006578:MADF domain" CG15845 11-Aug-17 DroID_v2017_08 "Drer\zgc:152938, Drer\si:ch73-59f11.3, Drer\si:ch211-207i20.3, Drer\LOC100330838" - "Cele\madf-4, Cele\madf-10, Cele\madf-2, Cele\madf-8, Cele\madf-5, Cele\madf-3, Cele\madf-9" - - - "lethal,recessive" FBgn0038439 Cad89D Cadherin 89D http://flybase.org/reports/FBgn0038439 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR020894 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "DCad89D, CG14900, CT34724, Cad89D" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site" CG14900 11-Aug-17 DroID_v2017_08 "Drer\cdhr5b, Drer\cdh16, Drer\cdh17, Drer\cdhr2, Drer\pcdh7a, Drer\cdh13, Drer\cdhr5a" - "Cele\cdh-8, Cele\cdh-3" - "Mmus\Pcdh7, Mmus\Pcdhb16, Mmus\Pcdhb15, Mmus\Pcdhb19, Mmus\Cdh13, Mmus\Cdhr2, Mmus\Cdh17, Mmus\Pcdhb21, Mmus\Pcdhb13, Mmus\Pcdhb10, Mmus\Pcdhb11, Mmus\Cdhr5" "Hsap\CDH13, Hsap\PCDHB5, Hsap\PCDHB16, Hsap\PCDHB10, Hsap\CDHR2, Hsap\CDHR5, Hsap\DCHS2, Hsap\CDH17" "viable,fertile,body color defective" mesothoracic tergum FBgn0040036 CG12550 - http://flybase.org/reports/FBgn0040036 protein_coding_gene - - - CG12550 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014141 cher cheerio http://flybase.org/reports/FBgn0014141 "FBgn0016063, FBgn0023208" protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from sequence or structural similarity with HGNC:3754 "motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype germline ring canal formation ; GO:0030725 | inferred from mutant phenotype germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype female germline ring canal formation, actin assembly ; GO:0008302 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype positive regulation of cytoskeleton organization ; GO:0051495 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype" actin filament ; GO:0005884 | colocalizes_with inferred from direct assay contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | colocalizes_with inferred from direct assay female germline ring canal inner rim ; GO:0035183 | inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay female germline ring canal outer rim ; GO:0035182 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay actin cytoskeleton ; GO:0015629 | inferred from direct assay "cher, CG3937, FLN, sko, Fil, Cher, joy, FLN90" "IPR001298:Filamin/ABP280 repeat, IPR001589:Actinin-type actin-binding domain, conserved site, IPR001715:Calponin homology domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR017868:Filamin/ABP280 repeat-like" CG3937 11-Aug-17 DroID_v2017_08 "Drer\flnbl, Drer\flnca, Drer\flna, Drer\flnb, Drer\flncb, Drer\LOC100534866" - "Cele\fln-1, Cele\fln-2" "Xtro\flna, Xtro\flnc, Xtro\flnb" "Mmus\Flnc, Mmus\Flna, Mmus\Flnb" "Hsap\FLNA, Hsap\FLNC, Hsap\FLNB" " adult stage , adult stage && oogenesis stage " " follicle cell

, inner nurse cell ring canal rim

, ring canal

, fusome

, outer nurse cell ring canal rim

, ovariole | surrounding

, ovariole

, nurse cell

, interfollicle cell

" "female sterile,recessive,learning defective,memory defective,neuroanatomy defective,viable,fertile,chemical sensitive,visible,short lived,locomotor behavior defective,uncoordinated,heat sensitive,male fertile,long lived" "nurse cell ring canal,egg chamber,border follicle cell,interfollicle cell,germarium region 2b & interfollicle cell,follicle cell,intersegmental nerve,ommatidium,ovary,ovariole,germarium,nurse cell,plasma membrane & nurse cell,plasma membrane & oocyte,nurse cell & nucleus,centripetally migrating follicle cell,nurse cell & plasma membrane,oocyte,inner nurse cell ring canal rim,lamellocyte,ectopic" FBgn0266109 mei-114 meiotic 114 http://flybase.org/reports/FBgn0266109 gene - female meiotic division ; GO:0007143 | inferred from mutant phenotype - mei-114 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,meiotic cell cycle defective,female" FBgn0014353 ms(3)ry5 ms(3)ry5 http://flybase.org/reports/FBgn0014353 FBgn0013666 gene - - - "ms(3)5, ms(3)ry5" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0027248 l(1)G0260 lethal (1) G0260 http://flybase.org/reports/FBgn0027248 - gene - - - l(1)G0260 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal,partially lethal - majority die,recessive" FBgn0013732 sced scrambled http://flybase.org/reports/FBgn0013732 FBgn0033082 protein_coding_gene - actin filament reorganization involved in cell cycle ; GO:0030037 | inferred from mutant phenotype pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay "CT9143, CG3273, sced, Sced" - CG3273 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive,fertile,female sterile,viable" "embryonic/larval hemocyte | third instar larval stage,cycle 9 embryo,maternal effect,cycle 10 embryo,cycle 11 embryo,cycle 12 embryo,cycle 13 embryo,cycle 14 embryo" FBgn0041177 Ubx::Akap\Ubx Ubx::Akap\Ubx http://flybase.org/reports/FBgn0041177 engineered_fusion_gene - - - Ubx::Akap\Ubx - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic metathoracic segment,embryonic abdominal segment 1,ectopic,leg,antenna,haltere,wing,embryonic epidermis,abdominal 1 ventral denticle belt,Kolbchen" FBgn0034194 CG15611 - http://flybase.org/reports/FBgn0034194 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with trio response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with trio cellular_component ; GO:0005575 | no biological data available CG15611 "IPR000219:Dbl homology (DH) domain, IPR011993:PH domain-like" CG15611 11-Aug-17 DroID_v2017_08 "Drer\quo, Drer\triob, Drer\arhgef25a, Drer\plekhg4, Drer\si:dkey-91i10.2, Drer\trioa, Drer\si:dkey-65j6.2, Drer\zgc:158766, Drer\LOC101883939, Drer\arhgef25b, Drer\arhgef40, Drer\kalrnb, Drer\kalrna" "Scer\CDC24, Scer\ROM1, Scer\ROM2" "Cele\tiam-1, Cele\unc-73, Cele\Y95B8A.12, Cele\cgef-1" "Xtro\kalrn, Xtro\arhgef40" "Mmus\Kalrn, Mmus\Arhgef25, Mmus\Arhgef40, Mmus\D630003M21Rik, Mmus\Trio, Mmus\Tiam1, Mmus\Plekhg4" "Hsap\PLEKHG4, Hsap\TRIO, Hsap\TIAM1, Hsap\PLEKHG4B, Hsap\ARHGEF25, Hsap\ARHGEF40, Hsap\KALRN" viable FBgn0267081 CR45525 - http://flybase.org/reports/FBgn0267081 non_protein_coding_gene - - - CR45525 - CR45525 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065299 l(2)SH1992 lethal (2) SH1992 http://flybase.org/reports/FBgn0065299 gene - - - "l(2)SH1992, l(2)SH2 1992" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265706 CR44513 - http://flybase.org/reports/FBgn0265706 non_protein_coding_gene - - - "lincRNA.399, CR44513" - CR44513 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069915 CG41138 - http://flybase.org/reports/FBgn0069915 protein_coding_gene - - - CG41138 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005572 l(3)85Eh lethal (3) 85Eh http://flybase.org/reports/FBgn0005572 - gene - - - l(3)85Eh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033924 CG8613 - http://flybase.org/reports/FBgn0033924 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR008928, InterPro:IPR012341" - - CG8613 "IPR008928:Six-hairpin glycosidase-like, IPR012336:Thioredoxin-like fold, IPR024705:Spermatogenesis-associated protein 20, IPR004879:Domain of unknown function DUF255" CG8613 11-Aug-17 DroID_v2017_08 Drer\spata20 - Cele\B0495.5 Xtro\spata20 Mmus\Spata20 Hsap\SPATA20 FBgn0000154 B Bar http://flybase.org/reports/FBgn0000154 - gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from mutant phenotype" leg disc development ; GO:0035218 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | non-traceable author statement imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Bar, BarH1, bar, BB, B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,visible,dominant,recessive,cold sensitive,viable,female fertile,lethal,male fertile,poor,neuroanatomy defective,fertile,male" "eye,wing,cold sensitive,macrochaeta,tarsal segment 4,anterior,tarsal segment 3,pretarsus,ommatidium,morphogenetic furrow,optic lobe,medial ocellus,unguis,femur,tibia,metatarsus" FBgn0024849 nkg nanking http://flybase.org/reports/FBgn0024849 - gene - Nebenkern assembly ; GO:0007287 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype - "ms(3)3915, nkg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,viable" "spermatozoon,primary spermatocyte cyst,spermatid & nucleus,Nebenkern" FBgn0065764 l(2)SH0475 lethal (2) SH0475 http://flybase.org/reports/FBgn0065764 gene - - - "l(2)SH0475, l(2)SH2 0475" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033048 CG7881 - http://flybase.org/reports/FBgn0033048 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 CG7881 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG7881 11-Aug-17 DroID_v2017_08 "Drer\slc17a7a, Drer\ppt1, Drer\si:ch1073-513e17.1, Drer\slc17a5, Drer\slc17a8, Drer\slc17a6b, Drer\slc17a6a" "Scer\YCT1, Scer\YIL166C, Scer\TNA1, Scer\FEN2, Scer\DAL5, Scer\VHT1, Scer\THI73, Scer\SEO1" "Cele\T22F3.7, Cele\M162.5, Cele\F56A4.10, Cele\slc-17.4, Cele\T19D12.9, Cele\T19D12.10, Cele\slc-17.2, Cele\F59A1.13, Cele\C01B4.7, Cele\vglu-2, Cele\C18H9.5, Cele\Y4C6B.3, Cele\W04C9.6, Cele\C01B4.8, Cele\T02B11.6, Cele\T22F3.10, Cele\slc-17.8, Cele\Y19D10A.8, Cele\eat-4, Cele\vglu-3, Cele\slc-17.3, Cele\Y51B9A.6, Cele\C39E9.7, Cele\K11G9.5, Cele\K08C7.1, Cele\F41C3.2, Cele\F10C2.7, Cele\T22F3.8, Cele\Y19D10A.11, Cele\T28H11.8, Cele\cima-1, Cele\Y4C6B.4, Cele\F56A4.12, Cele\D1046.4, Cele\Y19D10A.4, Cele\T22F3.11, Cele\Y15E3A.4, Cele\R10D12.1, Cele\F44E7.7, Cele\C35A5.3, Cele\C18D1.2, Cele\F11A5.9, Cele\slc-17.1, Cele\T27D12.1, Cele\Y19D10A.5, Cele\slc-17.5, Cele\M117.1, Cele\H11E01.2, Cele\T01H3.3, Cele\slc-17.9" - "Mmus\Slc17a5, Mmus\Slc17a2, Mmus\Slc17a7, Mmus\Slc17a1, Mmus\Slc17a6, Mmus\Slc17a8, Mmus\Slc17a3, Mmus\Slc17a4" "Hsap\SLC17A1, Hsap\SLC17A3, Hsap\SLC17A2, Hsap\SLC17A4, Hsap\SLC17A7, Hsap\SLC17A6, Hsap\SLC17A8, Hsap\SLC17A5" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0051171 CG31171 - http://flybase.org/reports/FBgn0051171 protein_coding_gene - - - CG31171 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033931 Obp50e Odorant-binding protein 50e http://flybase.org/reports/FBgn0033931 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "CG13939, Obp50e, DmelObp50e" IPR006170:Pheromone/general odorant binding protein CG13939 11-Aug-17 DroID_v2017_08 - - - - - - DRSC06434 E 0.012252043 0.51141493 0.09562802 1.659874165 -0.917623538 0.457580055 FBgn0267164 CR45604 - http://flybase.org/reports/FBgn0267164 non_protein_coding_gene - - - CR45604 - CR45604 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265263 CG42688 - http://flybase.org/reports/FBgn0265263 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42688, DMG8-chr2L.34.001, anon-SAGE:Wang-006" - CG42688 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013651 ms(2)ry7 ms(2)ry7 http://flybase.org/reports/FBgn0013651 - gene - - - "ms(2)7, ms(2)ry7" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0085346 CG34317 - http://flybase.org/reports/FBgn0085346 protein_coding_gene ribonuclease activity ; GO:0004540 | inferred from electronic annotation with InterPro:IPR002759 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR002759 cellular_component ; GO:0005575 | no biological data available "CG34317, Dromel_CG7950_FBtr0085563_CHCHD4inmorf_uORF" IPR002759:Ribonuclease P/MRP protein subunit CG34317 11-Aug-17 DroID_v2017_08 "Drer\chchd4b, Drer\chchd4a, Drer\rpp14" - - "Xtro\rpp14, Xtro\chchd4" "Mmus\Chchd4, Mmus\Rpp14" "Hsap\RPP14, Hsap\CHCHD4" FBgn0035989 CG3967 - http://flybase.org/reports/FBgn0035989 protein_coding_gene tubulin N-acetyltransferase activity ; GO:0019799 | inferred from biological aspect of ancestor with PANTHER:PTN000269078 alpha-tubulin acetylation ; GO:0071929 | inferred from biological aspect of ancestor with PANTHER:PTN000269078 behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from biological aspect of ancestor with PANTHER:PTN000269078 microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR007965 CG3967 "IPR007965:Gcn5-related N-acetyltransferase (GNAT) domain, ATAT-type" CG3967 11-Aug-17 DroID_v2017_08 Drer\atat1 - "Cele\mec-17, Cele\atat-2" Xtro\atat1 Mmus\Atat1 Hsap\ATAT1 "learning defective,hyperactive,conditional,chemical resistant,viable" FBgn0082630 S(CycE[JP])2.8 S(CycE[JP])2.8 http://flybase.org/reports/FBgn0082630 gene - - - S(CycE[JP])2.8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033680 CG13186 - http://flybase.org/reports/FBgn0033680 protein_coding_gene - - - "AAF58585, BcDNA:AT11581, CG13186" - CG13186 11-Aug-17 DroID_v2017_08 Drer\cenpa - - - Mmus\Selenoh Hsap\SELENOH FBgn0011295 CG11297 - http://flybase.org/reports/FBgn0011295 - protein_coding_gene - - - "P28, anon2L, anon-2L, anon-21DEa, CG11297" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003869 tta tetanic http://flybase.org/reports/FBgn0003869 - gene - - - tta - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive,female sterile,behavior defective" "wing,neck,abdomen,proboscis" FBgn0034737 CG11362 - http://flybase.org/reports/FBgn0034737 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11362 - CG11362 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262822 CR43193 - http://flybase.org/reports/FBgn0262822 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43193, CR43193, mdcds_58258" - CR43193 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266314 CR44979 - http://flybase.org/reports/FBgn0266314 non_protein_coding_gene - - - CR44979 - CR44979 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065375 l(2)SH1683 lethal (2) SH1683 http://flybase.org/reports/FBgn0065375 gene - - - "l(2)SH1683, l(2)SH2 1683" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265609 CR44427 - http://flybase.org/reports/FBgn0265609 non_protein_coding_gene - - - CR44427 - CR44427 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039319 CG13659 - http://flybase.org/reports/FBgn0039319 protein_coding_gene - - - CG13659 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG13659 11-Aug-17 DroID_v2017_08 - - "Cele\D1044.1, Cele\C29F7.2, Cele\C29F7.1, Cele\dhs-27, Cele\H06H21.8, Cele\nhr-246" - - - "viable,fertile" FBgn0021772 ms(3)P122 ms(3)P122 http://flybase.org/reports/FBgn0021772 - gene - - - ms(3)P122 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0263982 CG43731 - http://flybase.org/reports/FBgn0263982 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43731 - CG43731 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011210 shk shank http://flybase.org/reports/FBgn0011210 - gene - male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "ms(3)07735, shk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male sterile,recessive" "spermatid,Nebenkern" FBgn0014155 e(w[a])r "enhancer of white-apricot, recessive" http://flybase.org/reports/FBgn0014155 - gene - - - "e(w[a])r, e(w[a])" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015879 anon-48Ah anon-48Ah http://flybase.org/reports/FBgn0015879 - gene - - - "X, anon-48Ah" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014204 l(1)16Fk lethal (1) 16Fk http://flybase.org/reports/FBgn0014204 - gene - - - "HL-XIII, l(1)16Fk" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031414 eys eyes shut http://flybase.org/reports/FBgn0031414 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O97148 extracellular matrix structural constituent ; GO:0005201 | inferred from mutant phenotype" cell morphogenesis ; GO:0000902 | inferred from mutant phenotype temperature compensation of the circadian clock ; GO:0010378 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay non-motile cilium ; GO:0097730 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay cilium ; GO:0005929 | "CG7245, CG15389, CG15388, CT35437, CG33955, eys, spam, mAb21A6, spacemaker, Eys, Spam, 21A6, mAb 21A6, MAb21A6, SPAM, EYS, Eyes Shut" "IPR018097:EGF-like calcium-binding, conserved site, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR001881:EGF-like calcium-binding domain" CG33955 11-Aug-17 DroID_v2017_08 "Drer\efemp1, Drer\scube1, Drer\scube3, Drer\jag1a, Drer\matn3a, Drer\megf6b, Drer\adgrl4, Drer\fbln1, Drer\zgc:158328, Drer\sned1, Drer\crb2b, Drer\crb2a, Drer\LOC101884253, Drer\fbln7, Drer\sid4, Drer\col28a1a, Drer\svep1, Drer\LOC100535882, Drer\agrn, Drer\LOC100332841, Drer\jag2b, Drer\si:ch73-173h19.3, Drer\lama4, Drer\egflam, Drer\dlb, Drer\col28a1a, Drer\jag2a, Drer\dpy19l1l, Drer\ltbp3, Drer\LOC562634, Drer\jag1b, Drer\adgrf6" - "Cele\agr-1, Cele\F25D7.5, Cele\Y70G10A.2, Cele\T19D12.6" "Xtro\crb2, Xtro\matn4, Xtro\nell1, Xtro\ltbp4, Xtro\hspg2, Xtro\f12, Xtro\jag1, Xtro\egflam, Xtro\hgfac, Xtro\col14a1, Xtro\notch1, Xtro\svep1, Xtro\LOC100491172, Xtro\fbn1, Xtro\agrn" "Mmus\Tdgf1, Mmus\Ltbp4, Mmus\Scube3, Mmus\Habp2, Mmus\Fbn1, Mmus\Dll3, Mmus\Agrn, Mmus\Matn3, Mmus\Sned1, Mmus\Vwce, Mmus\Vwa1, Mmus\Hgfac, Mmus\Egfl7, Mmus\Jag2, Mmus\Scube2, Mmus\Crb2, Mmus\Jag1, Mmus\Ltbp1, Mmus\Hspg2, Mmus\Hmcn2, Mmus\Egflam, Mmus\Fbln7, Mmus\Col22a1, Mmus\Col28a1, Mmus\Dlk2, Mmus\Dlk1, Mmus\F12, Mmus\Svep1, Mmus\Cfc1, Mmus\Vwde, Mmus\Dll4" "Hsap\MATN3, Hsap\SNED1, Hsap\CRB2, Hsap\JAG2, Hsap\JAG1, Hsap\FBLN7, Hsap\SCUBE3, Hsap\COL14A1, Hsap\F12, Hsap\VWCE, Hsap\EGFLAM, Hsap\EYS, Hsap\SVEP1, Hsap\TDGF1, Hsap\CFC1, Hsap\DLK2, Hsap\DLL4, Hsap\CFC1B, Hsap\HSPG2, Hsap\EGFL7, Hsap\LTBP1, Hsap\HGFAC, Hsap\HABP2, Hsap\LOC100996717, Hsap\NOTCH2NL, Hsap\DLK1, Hsap\AGRN, Hsap\DLL3, Hsap\COL22A1, Hsap\VWA1, Hsap\SCUBE2" "locomotor rhythm defective,viable,uncoordinated,heat sensitive,locomotor behavior defective,flightless,neurophysiology defective" "photoreceptor cell,eye photoreceptor cell stalk,rhabdomere,ommatidium,rhabdomere of eye photoreceptor cell,conditional,chemical conditional,eye,ocellus retinula cell,ocellus rhabdomere,rhabdomerehs.PB,mechanosensory neuron,heat sensitive,Johnston organ,scolopale" FBgn0053319 CR33319 - http://flybase.org/reports/FBgn0053319 pseudogene_attribute - - - "CG18078, CR33319" - CR33319 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051562 CR31562 - http://flybase.org/reports/FBgn0051562 pseudogene_attribute - - - "CG15588, CG15587, CG31562, CR31562" - CR31562 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065905 l(2)SH0193 lethal (2) SH0193 http://flybase.org/reports/FBgn0065905 gene - - - "l(2)SH0193, l(2)SH2 0193" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039350 jigr1 jing interacting gene regulatory 1 http://flybase.org/reports/FBgn0039350 protein_coding_gene transcription regulatory region DNA binding ; GO:0044212 | inferred from sequence model with InterPro:IPR006578 regulation of gene expression ; GO:0010468 | inferred from sequence model with InterPro:IPR006578 nucleus ; GO:0005634 | inferred from sequence model with InterPro:IPR006578 "bs29f05.y1, jigr1, CG17383, JIGR-1, JIGR1" IPR006578:MADF domain CG17383 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-207i20.3, Drer\LOC100330838, Drer\zgc:152938" - "Cele\madf-3, Cele\madf-8, Cele\madf-2, Cele\madf-9, Cele\madf-10, Cele\madf-4, Cele\madf-5" - - - "neuroanatomy defective,visible,lethal - all die during larval stage,viable,fertile" "embryonic/larval central nervous system,wing,embryonic/larval hemocyte | third instar larval stage" FBgn0005598 yemG3a yema gene 3a http://flybase.org/reports/FBgn0005598 FBgn0004042 gene - - - "yG3a, yT3a, yemG3a" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && oogenesis stage , embryonic stage | early , embryonic stage | stage <=8 " " ovary

, organism

" FBgn0016852 l(1)N33 lethal (1) N33 http://flybase.org/reports/FBgn0016852 - gene - - - "l(1)N33, N33" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043062 Tl::Toll-6 Tl::Toll-6 http://flybase.org/reports/FBgn0043062 engineered_fusion_gene - - - Tl::Toll-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263653 CR43644 - http://flybase.org/reports/FBgn0263653 non_protein_coding_gene - - - CR43644 - CR43644 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267435 chp chaoptin http://flybase.org/reports/FBgn0267435 protein_coding_gene - microvillus organization ; GO:0032528 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from genetic interaction with prom homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay rhabdomere development ; GO:0042052 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay rhabdomere microvillus ; GO:0035996 | inferred from direct assay anchored component of plasma membrane ; GO:0046658 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay "chp, idl-A, 24B10, mAb24B10, Chp, Mab24B10, MAb 24B10, mAb 24B10, CT5040, MAb24B10, 516, Nsp, CG1744, BSH, mAB24B10, Chaoptin, CHP" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR000225:Armadillo, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype" CG1744 11-Aug-17 DroID_v2017_08 "Drer\chadla, Drer\lrrcc1, Drer\tlr18, Drer\tlr1, Drer\chadlb, Drer\chad" - "Cele\lron-9, Cele\lron-1, Cele\tol-1, Cele\pan-1, Cele\lron-2" "Xtro\chadl, Xtro\LOC100488097" "Mmus\Chadl, Mmus\Chad, Mmus\Tlr6, Mmus\Lrrcc1, Mmus\Tlr1" "Hsap\TLR6, Hsap\CHADL, Hsap\CHAD, Hsap\LRRCC1, Hsap\TLR10, Hsap\TLR1" larval stage && pupal stage " retina

, photoreceptor cell R1--8

, eye-antennal disc

" " larval stage--adult stage , pupal stage&&adult stage , pupal stage , larval stage&&pupal stage , larval stage && pupal stage " " retina

, medulla

, optic lobe

, photoreceptor cell | presumptive

, eye-antennal disc

, lamina

" FBgn0001806 l(1)Mc39 lethal (1) Mc39 http://flybase.org/reports/FBgn0001806 - gene - - - l(1)Mc39 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "macrochaeta,somatic clone" FBgn0011175 l(1)291-53 lethal (1) 291-53 http://flybase.org/reports/FBgn0011175 FBgn0010199 gene - - - "291-53, l(1)291-53" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,male sterile,visible" wing FBgn0004472 apo altered pattern orientation http://flybase.org/reports/FBgn0004472 - gene - - - "apo[S129], apo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visual behavior defective,recessive" FBgn0024565 l(3)L6710 lethal (3) L6710 http://flybase.org/reports/FBgn0024565 - gene - - - l(3)L6710 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011791 l(3)j4E6 lethal (3) j4E6 http://flybase.org/reports/FBgn0011791 - gene - - - l(3)j4E6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028942 CG16852 - http://flybase.org/reports/FBgn0028942 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "BG:BACR48E02.2, BcDNA:AT28681, CG16852" - CG16852 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034251 ND-51L1 NADH dehydrogenase (ubiquinone) 51 kDa subunit-like 1 http://flybase.org/reports/FBgn0034251 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR001949 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR011537 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR001949, InterPro:IPR011537, InterPro:IPR019575 FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR001949, InterPro:IPR011537" "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with WB:WBGene00003831" - "CG11423, NUBM, ND-51L1" "IPR001949:NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site, IPR011537:NADH ubiquinone oxidoreductase, F subunit, IPR011538:NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain, IPR019575:NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain" CG11423 11-Aug-17 DroID_v2017_08 Drer\ndufv1 - Cele\nuo-1 Xtro\ndufv1 Mmus\Ndufv1 Hsap\NDUFV1 viable FBgn0065599 l(2)SH0875 lethal (2) SH0875 http://flybase.org/reports/FBgn0065599 gene - - - l(2)SH0875 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052640 CG32640 - http://flybase.org/reports/FBgn0052640 protein_coding_gene - - - CG32640 "IPR001623:DnaJ domain, IPR018253:DnaJ domain, conserved site" CG32640 11-Aug-17 DroID_v2017_08 - Scer\HLJ1 Cele\dnj-26 - - - "viable,fertile" FBgn0004855 RpII15 RNA polymerase II 15kD subunit http://flybase.org/reports/FBgn0004855 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR012164 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001222 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9196 inferred from sequence or structural similarity with SGD:S000003038" mRNA cleavage ; GO:0006379 | inferred from electronic annotation with InterPro:IPR034012 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9196 inferred from sequence or structural similarity with SGD:S000003038 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9196 inferred from sequence or structural similarity with SGD:S000003038 nucleus ; GO:0005634 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from direct assay" "pol II, Pol II, RNAP, PolII, RNApolII, RNAP II, H5, polII, dRPB9, RNA Pol II, RNA pol II, CG3284, RNA polII, RPII15, RpII215, l(3)Z23, l(3)88Be, RpII15, Rpb9" "IPR001222:Zinc finger, TFIIS-type, IPR001529:DNA-directed RNA polymerase, M/15kDa subunit, IPR019761:DNA-directed RNA polymerase M, 15kDa subunit, conserved site, IPR012164:DNA-directed RNA polymerase subunit/transcription factor S, IPR034012:Pol II subunit B9, C-terminal zinc ribbon" CG3284 11-Aug-17 DroID_v2017_08 Drer\polr2i Scer\RPB9 Cele\rpb-9 Xtro\polr2i Mmus\Polr2i Hsap\POLR2I " embryonic stage -- adult stage , adult stage , embryonic stage , larval stage "

ubiquitous "lethal,polyphasic,recessive,wild-type,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "capitellum,ganglion mother cell" DRSC16832 K -1.030864731 1.445908083 -0.478544839 -0.418832344 1.972142923 3.033536975 FBgn0002147 l(2)K513 lethal (2) K513 http://flybase.org/reports/FBgn0002147 - gene - - - l(2)K513 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025454 Cyp6g1 Cyp6g1 http://flybase.org/reports/FBgn0025454 "FBgn0003288, FBgn0067801, FBgn0067802" protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 response to insecticide ; GO:0017085 | inferred from mutant phenotype response to DDT ; GO:0046680 | inferred from mutant phenotype insecticide catabolic process ; GO:0046701 | inferred from direct assay response to organophosphorus ; GO:0046683 | inferred from mutant phenotype response to mercury ion ; GO:0046689 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern" - "Cyp6g1, Cyp6gl, CG8453, Rst(2)DDT, 6g1, cyp6g1, RDDT, RI, RI[II], RI[DDT], Cyp6-like, anon-WO03025223.17, anon-WO03025223.16, DDT-R, CYP6G1, Cyp6G1, CYP6g1, Dmel-Cyp6g1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG8453 11-Aug-17 DroID_v2017_08 "Drer\cyp3c2, Drer\cyp3c4, Drer\cyp3c3, Drer\cyp3a65, Drer\tbxas1, Drer\cyp3c1" Scer\ERG11 "Cele\cyp-13A11, Cele\cyp-13B2, Cele\cyp-13A5, Cele\cyp-25A3, Cele\cyp-43A1, Cele\cyp-25A6, Cele\cyp-13A12, Cele\cyp-25A1, Cele\cyp-13A10, Cele\cyp-13A6, Cele\cyp-13A7, Cele\cyp-13A8, Cele\cyp-25A2, Cele\cyp-13A4, Cele\cyp-13B1, Cele\cyp-13A1, Cele\cyp-13A3, Cele\cyp-25A4, Cele\cyp-13A2, Cele\cyp-44A1" "Xtro\tbxas1, Xtro\LOC100494419, Xtro\cyp3a5, Xtro\cyp3a4" "Mmus\Cyp3a57, Mmus\Cyp3a41a, Mmus\Cyp3a59, Mmus\Tbxas1, Mmus\Cyp3a11, Mmus\Cyp3a25, Mmus\Cyp3a41b, Mmus\Cyp3a44, Mmus\Cyp3a13, Mmus\Cyp3a16" "Hsap\CYP3A7-CYP3A51P, Hsap\TBXAS1, Hsap\CYP3A43, Hsap\CYP3A7, Hsap\CYP3A5, Hsap\CYP3A4" "viable,fertile,chemical sensitive,chemical resistant,maternal effect" FBgn0043058 Trl::ttk Trl::ttk http://flybase.org/reports/FBgn0043058 engineered_fusion_gene - - - Trl::ttk - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" eye FBgn0267242 CR45682 - http://flybase.org/reports/FBgn0267242 non_protein_coding_gene - - - CR45682 - CR45682 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002864 Mst95EF Male-specific RNA 95EF http://flybase.org/reports/FBgn0002864 - gene - - - "mst345, Mst95EF" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001488 l(1)10Ah lethal (1) 10Ah http://flybase.org/reports/FBgn0001488 - gene - - - "l(1)G12, l(1)10Ah" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035537 CG11342 - http://flybase.org/reports/FBgn0035537 protein_coding_gene "methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR010675, InterPro:IPR024160" - - CG11342 "IPR010675:RNA methyltransferase bin3, C-terminal, IPR024160:Bin3-type S-adenosyl-L-methionine binding domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG11342 11-Aug-17 DroID_v2017_08 "Drer\si, Drer\bcdin3d, Drer\mepce, Drer\si:ch1073-157b13.1" - - Xtro\bcdin3d "Mmus\Mepce, Mmus\Bcdin3d" "Hsap\MEPCE, Hsap\BCDIN3D" viable FBgn0261292 CheB53a Chemosensory protein B 53a http://flybase.org/reports/FBgn0261292 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CheB53a, CG33457, CG16797, CG33550" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG33550 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267002 unc-104 uncoordinated-104 http://flybase.org/reports/FBgn0267002 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" synaptic vesicle maturation ; GO:0016188 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype filopodium assembly ; GO:0046847 | inferred from mutant phenotype regulation of synapse assembly ; GO:0051963 | inferred from mutant phenotype positive regulation of insulin secretion ; GO:0032024 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype anterograde axonal transport ; GO:0008089 | inferred from mutant phenotype axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype regulation of locomotion ; GO:0040012 | inferred from mutant phenotype anterograde synaptic vesicle transport ; GO:0048490 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype vesicle transport along microtubule ; GO:0047496 | inferred from mutant phenotype axon ; GO:0030424 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from mutant phenotype dendrite ; GO:0030425 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 "unc-104, KIF1A, bris, imac, Unc-104, CG8566, unc104, KIF1A/1B, DUnc-104, DmDUnc104, KIF 1B, DUNC104, DmKlp53D, Klp53D, DmCG8566, Dunc104, Unc104, Imac" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000253:Forkhead-associated (FHA) domain, IPR001752:Kinesin motor domain, IPR001849:Pleckstrin homology domain, IPR008984:SMAD/FHA domain, IPR011993:PH domain-like, IPR019821:Kinesin motor domain, conserved site, IPR022140:Kinesin-like KIF1-type, IPR022164:Kinesin-like, IPR032405:Kinesin-associated" CG8566 11-Aug-17 DroID_v2017_08 "Drer\kif16ba, Drer\stard9, Drer\ap2b1, Drer\kif1c, Drer\kif1ab, Drer\si:ch73-375g18.1, Drer\kif1b, Drer\kif14, Drer\kif1aa, Drer\kif13ba, Drer\kif16bb, Drer\si:rp71-84d9.2, Drer\kif13bb, Drer\kif13a" "Scer\KIP2, Scer\KIP1, Scer\CIN8" "Cele\unc-104, Cele\klp-6, Cele\klp-4" "Xtro\kif1a, Xtro\kif16b, Xtro\kif1c, Xtro\kif14, Xtro\kif13b, Xtro\kif1b" "Mmus\Kif16b, Mmus\Kif1c, Mmus\Kif14, Mmus\Gm1305, Mmus\Stard9, Mmus\Kif1b, Mmus\Kif13a, Mmus\Kif1a, Mmus\Kif13b" "Hsap\KIF13A, Hsap\KIF1C, Hsap\KIF1B, Hsap\KIF14, Hsap\KIF16B, Hsap\KIF13B, Hsap\KIF1A, Hsap\STARD9" FBgn0040238 Best1 Bestrophin 1 http://flybase.org/reports/FBgn0040238 protein_coding_gene volume-sensitive chloride channel activity ; GO:0072320 | inferred from direct assay intracellular calcium activated chloride channel activity ; GO:0005229 | inferred from mutant phenotype volume-sensitive chloride channel activity ; GO:0072320 | inferred from mutant phenotype chloride channel activity ; GO:0005254 | inferred from direct assay cell volume homeostasis ; GO:0006884 | inferred from direct assay cellular water homeostasis ; GO:0009992 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay cell volume homeostasis ; GO:0006884 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay "best, CG6264, dmBest1, dbest1, Dbest, anon-WO0118547.380, Best1, dBest1" "IPR000615:Bestrophin, IPR021134:Bestrophin/UPF0187" CG6264 11-Aug-17 DroID_v2017_08 "Drer\best2, Drer\best1, Drer\best4" - "Cele\best-3, Cele\best-17, Cele\best-6, Cele\sma-10, Cele\C09B9.85, Cele\best-2, Cele\best-12, Cele\best-10, Cele\best-24, Cele\best-14, Cele\best-20, Cele\best-4, Cele\best-21, Cele\best-11, Cele\best-16, Cele\best-8, Cele\best-9, Cele\best-23, Cele\best-5, Cele\best-13, Cele\best-25, Cele\best-19, Cele\best-26, Cele\best-15, Cele\best-18, Cele\best-22, Cele\best-7, Cele\best-1" "Xtro\best1, Xtro\best3, Xtro\best4, Xtro\best2" "Mmus\Best1, Mmus\Best3, Mmus\Best2" "Hsap\BEST4, Hsap\BEST2, Hsap\BEST3, Hsap\BEST1" "viable,fertile" FBgn0083014 snoRNA:Psi18S-996 snoRNA:Psi18S-996 http://flybase.org/reports/FBgn0083014 snoRNA_gene - - - "snoRNA:Psi18S-996, psi18s-996, Psi 18S-996, CR34630, chr3L:245309..245488" - CR34630 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031209 Ir21a Ionotropic receptor 21a http://flybase.org/reports/FBgn0031209 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "CT8983, Ir21a, IR21a, CG2657, DmelIR21a, ir21a" IPR001320:Ionotropic glutamate receptor CG2657 11-Aug-17 DroID_v2017_08 "Drer\grid1a, Drer\grid1b, Drer\LOC100537813" - Cele\W02A2.5 - "Mmus\Grik4, Mmus\Grid1" Hsap\GRID1 "partially lethal - majority die,some die during pupal stage,viable,fertile" FBgn0065804 l(2)SH0398 lethal (2) SH0398 http://flybase.org/reports/FBgn0065804 gene - - - "l(2)SH0398, l(2)SH2 0398" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044495 DTD45.11 DTD45.11 http://flybase.org/reports/FBgn0044495 gene - - - DTD45.11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265960 CR44747 - http://flybase.org/reports/FBgn0265960 non_protein_coding_gene - - - "lincRNA.24, CR44747" - CR44747 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046711 GIIIA GIIIA http://flybase.org/reports/FBgn0046711 gene phospholipase A2 activity ; GO:0004623 | non-traceable author statement - extracellular region ; GO:0005576 | non-traceable author statement "dGIIIA, GIIIA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004575 Syn Synapsin http://flybase.org/reports/FBgn0004575 - protein_coding_gene - neurotransmitter secretion ; GO:0007269 | inferred from electronic annotation with InterPro:IPR001359 male courtship behavior ; GO:0008049 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity response to heat ; GO:0009408 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype optomotor response ; GO:0071632 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype synaptic vesicle ; GO:0008021 | inferred from electronic annotation with InterPro:IPR001359 terminal bouton ; GO:0043195 | inferred from direct assay "syn, CG3985, SYN2, SYN1, Dsyn-1, Syn, SYN" "IPR001359:Synapsin, IPR016185:Pre-ATP-grasp domain, IPR020897:Synapsin, pre-ATP-grasp domain, IPR020898:Synapsin, ATP-binding domain" CG3985 11-Aug-17 DroID_v2017_08 "Drer\syn3, Drer\syn2a, Drer\syn2b, Drer\syn1" - Cele\snn-1 "Xtro\syn2, Xtro\syn3" "Mmus\Syn2, Mmus\Syn3, Mmus\Syn1" "Hsap\SYN2, Hsap\SYN3, Hsap\SYN1" "viable,fertile,learning defective,short lived,locomotor behavior defective,optomotor response defective,jump response defective,chemical resistant,memory defective,courtship behavior defective,male" FBgn0002913 mwi misheld wings http://flybase.org/reports/FBgn0002913 - gene - - - mwi - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,viable,good,male,female,reduced,female fertile,visible,recessive" "wing,eye" FBgn0034706 CG11275 - http://flybase.org/reports/FBgn0034706 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000698511 "i188, CG11275" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG11275 11-Aug-17 DroID_v2017_08 "Drer\kbtbd4, Drer\klhl11, Drer\spopla, Drer\spop, Drer\spoplb" Scer\YIL001W "Cele\hpo-9, Cele\bath-40, Cele\bath-43, Cele\bath-42" - "Mmus\Kbtbd4, Mmus\Spop, Mmus\Gm4858, Mmus\Tdpoz1, Mmus\Gm10696, Mmus\Tdpoz5, Mmus\Klhl11, Mmus\Tdpoz3, Mmus\Tdpoz4, Mmus\Gm9125, Mmus\Tdpoz2, Mmus\Spopl" "Hsap\KBTBD4, Hsap\SPOPL, Hsap\KLHL11, Hsap\SPOP" DRSC04095 E 0.020832688 0.2044938 -1.748534365 0.048734281 0.331738649 0.094925004 FBgn0029838 CG4666 - http://flybase.org/reports/FBgn0029838 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4666 IPR029069:HotDog domain CG4666 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-52e5.1, Drer\si:ch73-52e5.2" Scer\YBR096W - Xtro\them6 Mmus\Them6 Hsap\THEM6 viable FBgn0021874 Nle Notchless http://flybase.org/reports/FBgn0021874 FBgn0042663 protein_coding_gene Notch binding ; GO:0005112 | traceable author statement Notch signaling pathway ; GO:0007219 | traceable author statement ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000457354 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000457354 ribosome ; GO:0005840 | inferred from biological aspect of ancestor with PANTHER:PTN000457354 "l(2)k13714, anon-WO0026364, CG2863, Nle" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001632:G-protein, beta subunit, IPR001680:WD40 repeat, IPR012972:NLE, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG2863 11-Aug-17 DroID_v2017_08 Drer\nle1 Scer\RSA4 "Cele\H24G06.1, Cele\W07E6.2, Cele\dyci-1" Xtro\nle1 Mmus\Nle1 Hsap\NLE1 "lethal,recessive,viable,male sterile,wild-type,partially lethal - majority die,visible" "microchaeta,trichogen cell,mesothoracic tergum,wing hair,supernumerary" FBgn0024654 l(2)k08139 lethal (2) k08139 http://flybase.org/reports/FBgn0024654 - gene - - - "81/39, l(2)k08139" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0027617 CG5808 - http://flybase.org/reports/FBgn0027617 - protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "BcDNA:GH01073, UKL, cg5808, CG5808" "IPR000504:RNA recognition motif domain, IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain" CG5808 11-Aug-17 DroID_v2017_08 Drer\ppil4 "Scer\CPR5, Scer\CPR2, Scer\CWC27" Cele\sig-7 Xtro\ppil4 "Mmus\Rbm7, Mmus\Ppil4, Mmus\Gm3376, Mmus\Rbmy" "Hsap\RBMY1E, Hsap\SNRNP35, Hsap\PPIL4, Hsap\RBMY1B, Hsap\RBMY1D, Hsap\RBMY1A1" "visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "adult thorax,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0015959 l(2)35Fg lethal (2) 35Fg http://flybase.org/reports/FBgn0015959 - gene - spermatid differentiation ; GO:0048515 | inferred from mutant phenotype - l(2)35Fg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,male sterile" FBgn0029755 Sas10 Something about silencing 10 http://flybase.org/reports/FBgn0029755 protein_coding_gene - "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000326128 neurogenesis ; GO:0022008 | inferred from mutant phenotype" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000326128 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000326128 "sas-10, dSAS10, CG4202, l(1)G0106, Sas10, sas10" "IPR007146:Sas10/Utp3/C1D, IPR018972:Sas10 C-terminal domain" CG4202 11-Aug-17 DroID_v2017_08 Drer\utp3 Scer\SAS10 Cele\T01B7.5 Xtro\utp3 Mmus\Utp3 Hsap\UTP3 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,partially lethal - majority die,visible,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,trichogen cell" FBgn0085330 CG34301 - http://flybase.org/reports/FBgn0085330 protein_coding_gene - - - CG34301 - CG34301 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061020 l(3)S025266 lethal (3) S025266 http://flybase.org/reports/FBgn0061020 gene - - - "0252/66, l(3)S025266" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0034224 insb insensible http://flybase.org/reports/FBgn0034224 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with H nucleus ; GO:0005634 | inferred from direct assay "CG6520, insb" - CG6520 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,macrochaeta" DRSC24404 K -0.385707856 0.006611337 0.490970354 0.514074723 2.713528397 1.767185721 FBgn0037606 CG8032 - http://flybase.org/reports/FBgn0037606 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" - CG8032 "IPR002937:Amine oxidase, IPR023753:FAD/NAD(P)-binding domain" CG8032 11-Aug-17 DroID_v2017_08 "Drer\smox, Drer\si:dkey-275b16.2, Drer\zgc:66484, Drer\kdm1a, Drer\paox1" Scer\FMS1 "Cele\amx-1, Cele\hpo-15, Cele\spr-5, Cele\amx-3" "Xtro\paox, Xtro\smox, Xtro\kdm1b, Xtro\kdm1a, Xtro\LOC100145496" "Mmus\Paox, Mmus\Smox, Mmus\Kdm1a" "Hsap\KDM1A, Hsap\SMOX, Hsap\PAOX, Hsap\KDM1B" viable FBgn0051480 tRNA:Thr-CGT-1-1 transfer RNA:Threonine-CGT 1-1 http://flybase.org/reports/FBgn0051480 tRNA_gene ACG codon-amino acid adaptor activity ; GO:0033440 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033440 cytosol ; GO:0005829 | inferred by curator from GO:0033440 "AE002708.trna23-ThrCGT, tRNA[Thr][[4]], tRNA[Thr][[3]], tRNA:T3:93AB, tRNA:thr4:93A, tRNA:T4:93A, tRNA:T:CGT:AE002708-a, CR31480, tRNA[[Thr]], chr3R.trna29-ThrCGT, tRNA-Thr-CGT-1-1, tRNA:Thr-CGT-1-1, tRNA:CR31480, ACG" - CR31480 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085380 CG34351 - http://flybase.org/reports/FBgn0085380 protein_coding_gene - - - "CG34351, CG11928, CG15633, ORE-3" IPR026512:RGS7BP/RGS9BP family CG34351 11-Aug-17 DroID_v2017_08 "Drer\rgs7bpa, Drer\si:ch73-167i17.6, Drer\zgc:109913, Drer\rgs7bpb" - Cele\rsbp-1 "Xtro\rgs7bp, Xtro\rgs9bp" "Mmus\Rgs9bp, Mmus\Rgs7bp" "Hsap\RGS7BP, Hsap\RGS9BP" viable FBgn0030666 CG12708 - http://flybase.org/reports/FBgn0030666 protein_coding_gene - - - CG12708 IPR032057:Protein of unknown function DUF4799 CG12708 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0031302 CG14340 - http://flybase.org/reports/FBgn0031302 protein_coding_gene - vesicle-mediated transport ; GO:0016192 | inferred from electronic annotation with InterPro:IPR010989 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR010989 CG14340 "IPR010989:SNARE, IPR026512:RGS7BP/RGS9BP family" CG14340 11-Aug-17 DroID_v2017_08 "Drer\rgs7bpb, Drer\si:ch73-167i17.6, Drer\zgc:109913, Drer\rgs7bpa" - Cele\rsbp-1 Xtro\rgs7bp "Mmus\Rgs7bp, Mmus\Rgs9bp" "Hsap\RGS9BP, Hsap\RGS7BP" FBgn0015957 l(1)6Fd lethal (1) 6Fd http://flybase.org/reports/FBgn0015957 - gene - - - "l, l(1)6Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263236 SP1029 SP1029 http://flybase.org/reports/FBgn0263236 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 lateral inhibition ; GO:0046331 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "SP1029, CG11956, ptl, ptls" "IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR024571:ERAP1-like C-terminal domain, IPR034016:Aminopeptidase N-type" CG11956 11-Aug-17 DroID_v2017_08 "Drer\lnpep, Drer\erap1b, Drer\enpep, Drer\si:ch211-149p5.1, Drer\si:ch211-276a23.5, Drer\npepps, Drer\erap1a, Drer\si:ch211-198g19.1, Drer\anpepb, Drer\erap2, Drer\anpepa, Drer\si:ch211-106j24.1" "Scer\APE2, Scer\TMA108, Scer\AAP1" "Cele\T07F10.1, Cele\R03G8.6, Cele\VB0395L.1, Cele\pam-1, Cele\T12E12.6, Cele\AC3.5, Cele\mnp-1, Cele\T16G12.1, Cele\F49B2.6, Cele\R03G8.4, Cele\Y53F4B.20, Cele\Y42A5A.1, Cele\Y67D8C.9" "Xtro\lvrn, Xtro\enpep, Xtro\lnpep, Xtro\npepps, Xtro\anpep, Xtro\erap1" "Mmus\Anpep, Mmus\Enpep, Mmus\Npepps, Mmus\Erap1, Mmus\Trhde, Mmus\Lvrn, Mmus\Lnpep" "Hsap\ANPEP, Hsap\ENPEP, Hsap\NPEPPS, Hsap\ERAP2, Hsap\LVRN, Hsap\ERAP1, Hsap\LNPEP, Hsap\TRHDE" FBgn0027172 l(2)B1 lethal (2) B1 http://flybase.org/reports/FBgn0027172 - gene - - - l(2)B1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002334 l(3)87Bb lethal (3) 87Bb http://flybase.org/reports/FBgn0002334 - gene - - - "ck14, l(3)ck14, l(3)87Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0034936 CG2970 - http://flybase.org/reports/FBgn0034936 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001972 "CG2970, SD03319p" "IPR001107:Band 7 domain, IPR001972:Stomatin family, IPR032435:Band 7, C-terminal extension" CG2970 11-Aug-17 DroID_v2017_08 "Drer\zgc:112408, Drer\stom, Drer\stoml2, Drer\stoml3b, Drer\stoml3a" - "Cele\mec-2, Cele\stl-1, Cele\sto-2, Cele\sto-1" Xtro\stoml2 "Mmus\Stom, Mmus\Stoml2, Mmus\Stoml3" "Hsap\STOML3, Hsap\STOM, Hsap\STOML2" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0264832 CG44040 - http://flybase.org/reports/FBgn0264832 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44040 - CG44040 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065356 l(2)SH1760 lethal (2) SH1760 http://flybase.org/reports/FBgn0065356 gene - - - "l(2)SH1760, l(2)SH2 1760" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052446 Atox1 Antioxidant 1 copper chaperone http://flybase.org/reports/FBgn0052446 protein_coding_gene copper chaperone activity ; GO:0016531 | inferred from biological aspect of ancestor with PANTHER:PTN001106576 intracellular copper ion transport ; GO:0015680 | inferred from biological aspect of ancestor with PANTHER:PTN001106576 cellular copper ion homeostasis ; GO:0006878 | inferred from biological aspect of ancestor with PANTHER:PTN001106576 response to oxidative stress ; GO:0006979 | inferred from biological aspect of ancestor with PANTHER:PTN001106576 copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000517250 "CG12562, Atox1, CG32446, DmAtox1" "IPR006121:Heavy metal-associated domain, HMA" CG32446 11-Aug-17 DroID_v2017_08 Drer\atox1 Scer\ATX1 Cele\cuc-1 Xtro\atox1 Mmus\Atox1 Hsap\ATOX1 "wild-type,partially lethal - majority die,fertile,lethal,chemical conditional,viable" FBgn0060633 l(3)S085203 lethal (3) S085203 http://flybase.org/reports/FBgn0060633 gene - - - "0852/03, l(3)S085203" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0016858 l(1)N5 lethal (1) N5 http://flybase.org/reports/FBgn0016858 - gene - - - "l(1)N5, N5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027211 l(1)G0355 lethal (1) G0355 http://flybase.org/reports/FBgn0027211 - gene - - - l(1)G0355 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0011535 l(3)00945 lethal (3) 00945 http://flybase.org/reports/FBgn0011535 - gene - - - l(3)00945 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028121 l(3)S059706 lethal (3) S059706 http://flybase.org/reports/FBgn0028121 gene - - - l(3)S059706 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052359 tRNA:Leu-CAG-1-3 transfer RNA:Leucine-CAG 1-3 http://flybase.org/reports/FBgn0052359 tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "AE002602.trna9-LeuCAG, tRNA:L:CAG:AE002602-e, CR32359, chr3L.trna43-LeuCAG, tRNA-Leu-CAG-1-3, tRNA:Leu-CAG-1-3, tRNA:CR32359, CUG" - CR32359 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011212 bet betel http://flybase.org/reports/FBgn0011212 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(3)04066, bet" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0032746 CG10470 - http://flybase.org/reports/FBgn0032746 protein_coding_gene calcium channel activity ; GO:0005262 | inferred from electronic annotation with InterPro:IPR008559 endoplasmic reticulum calcium ion homeostasis ; GO:0032469 | inferred from electronic annotation with InterPro:IPR008559 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from electronic annotation with InterPro:IPR008559 "TuB2, TUB2, TU37B2, B2, anon-37B-2, CG10470" "IPR008559:Calcium load-activated calcium channel, IPR002809:Integral membrane protein EMC3/TMCO1-like" CG10470 11-Aug-17 DroID_v2017_08 Drer\tmco1 - Cele\F22B5.10 Xtro\tmco1 Mmus\Tmco1 Hsap\TMCO1 viable FBgn0266568 yar yellow-achaete intergenic RNA http://flybase.org/reports/FBgn0266568 non_protein_coding_gene - "regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay "yar, CR42744, anon-1Be" - CR42744 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029996 UbcE2H Ubiquitin conjugating enzyme E2H http://flybase.org/reports/FBgn0029996 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12484 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000630520 lateral inhibition ; GO:0046331 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12484 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "dUbc-E2H, CG2257, UbcE2H, Ubc-E2H, Ubc-E2Hs, ubcE2h, UbcDE2H" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG2257 11-Aug-17 DroID_v2017_08 Drer\ube2h Scer\UBC8 Cele\ubc-8 Xtro\ube2h Mmus\Ube2h Hsap\UBE2H "lethal,recessive,viable,visible,body color defective,stress response defective" "chaeta,supernumerary,mesothoracic tergum" DRSC18221 K 1.108765544 -1.432740002 -0.090545954 0.468259198 1.716623345 0.861211737 FBgn0032154 mtDNA-helicase mitochondrial DNA helicase http://flybase.org/reports/FBgn0032154 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR007694 single-stranded DNA binding ; GO:0003697 | inferred from sequence or structural similarity with UniProtKB:Q96RR1 single-stranded DNA binding ; GO:0003697 | inferred from direct assay double-stranded DNA binding ; GO:0003690 | inferred from direct assay 5'-3' DNA helicase activity ; GO:0043139 | inferred from sequence or structural similarity with UniProtKB:Q96RR1 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from direct assay" mitochondrial genome maintenance ; GO:0000002 | inferred from mutant phenotype mitochondrial DNA replication ; GO:0006264 | inferred from sequence or structural similarity with UniProtKB:Q96RR1 protein homooligomerization ; GO:0051260 | inferred from direct assay mitochondrial nucleoid ; GO:0042645 | inferred from sequence or structural similarity with UniProtKB:Q96RR1 mitochondrion ; GO:0005739 | inferred from direct assay "mtDNA-helicase, CG5924, mtDNA helicase" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR007694:DNA helicase, DnaB-like, C-terminal" CG5924 11-Aug-17 DroID_v2017_08 "Drer\peo1, Drer\poln" - Cele\F46G11.1 Xtro\c10orf2 "Mmus\Twnk, Mmus\Poln" "Hsap\POLN, Hsap\TWNK" "cell growth defective,viable,fertile,increased cell death,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing disc | third instar larval stage,wing disc,posterior compartment | third instar larval stage" FBgn0082961 snoRNA:Psi28S-3385b snoRNA:Psi28S-3385b http://flybase.org/reports/FBgn0082961 snoRNA_gene - - - "snoRNA:Psi28S-3385b, psi28s-3385b, CR34607" - CR34607 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266648 CR45155 - http://flybase.org/reports/FBgn0266648 non_protein_coding_gene - - - CR45155 - CR45155 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033523 CG12895 - http://flybase.org/reports/FBgn0033523 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "protein-FAD linkage ; GO:0018293 | inferred from sequence or structural similarity with UniProtKB:Q9NX18 mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from sequence or structural similarity with UniProtKB:Q9NX18 protein-FAD linkage ; GO:0018293 | inferred from biological aspect of ancestor with PANTHER:PTN002287625 mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from biological aspect of ancestor with PANTHER:PTN000279729 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN002287625 mitochondrial respiratory chain complex II assembly ; GO:0034553 | inferred from biological aspect of ancestor with PANTHER:PTN000279729" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9NX18 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000279729 "BcDNA:RE29446, CG12895" "IPR005631:Flavinator of succinate dehydrogenase, IPR028882:Succinate dehydrogenase assembly factor 2, mitochondrial" CG12895 11-Aug-17 DroID_v2017_08 Drer\sdhaf2 Scer\SDH5 Cele\Y57A10A.29 Xtro\sdhaf2 Mmus\Sdhaf2 Hsap\SDHAF2 "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0041125 l(2)45Al lethal (2) 45Al http://flybase.org/reports/FBgn0041125 gene - - - l(2)45Al - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0027336 l(1)40b lethal (1) 40b http://flybase.org/reports/FBgn0027336 - gene - - - l(1)40b - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025681 CG3558 - http://flybase.org/reports/FBgn0025681 FBgn0031487 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "FBgn0025681, c4.3, BEST:LD23852, CG3558, LD23852" "IPR019384:Retinoic acid induced 16-like protein, IPR011989:Armadillo-like helical" CG3558 11-Aug-17 DroID_v2017_08 "Drer\fam160b1, Drer\fam160a2, Drer\fam160b2, Drer\fam160a1a" - Cele\C05D11.8 "Xtro\fam160b1, Xtro\fam160b2, Xtro\fam160a1, Xtro\fam160a2" "Mmus\Fam160a2, Mmus\Fam160a1, Mmus\Fam160b1, Mmus\Fam160b2" "Hsap\FAM160B2, Hsap\FAM160A2, Hsap\FAM160B1, Hsap\FAM160A1" FBgn0259162 RunxB Runt related B http://flybase.org/reports/FBgn0259162 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR008967, InterPro:IPR012346, InterPro:IPR013524 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000040 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR012346, InterPro:IPR013524" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR008967, InterPro:IPR012346, InterPro:IPR013524" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR012346" "CG42267, CG15455, CG15454, RunxB" "IPR000040:Acute myeloid leukemia 1 protein (AML1)/Runt, IPR008967:p53-like transcription factor, DNA-binding, IPR012346:p53/RUNT-type transcription factor, DNA-binding domain, IPR013524:Runt domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG42267 11-Aug-17 DroID_v2017_08 "Drer\runx3, Drer\runx2a, Drer\runx1, Drer\runx2b" - Cele\rnt-1 "Xtro\runx1, Xtro\runx3, Xtro\runx2" "Mmus\Runx2, Mmus\Runx1, Mmus\Runx3" "Hsap\RUNX1, Hsap\RUNX3, Hsap\RUNX2" FBgn0011055 l(1)Q8 lethal (1) Q8 http://flybase.org/reports/FBgn0011055 FBgn0010210 gene - - - l(1)Q8 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028657 anon-1Ca anon-1Ca http://flybase.org/reports/FBgn0028657 gene - - - "X, anon-1Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082620 S(CycE[JP])47S8 S(CycE[JP])47S8 http://flybase.org/reports/FBgn0082620 gene - - - "47S8, S(CycE[JP])47S8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037877 CG6689 - http://flybase.org/reports/FBgn0037877 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612, InterPro:IPR013087" - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "dmCG6689, CG6689" "IPR006612:Zinc finger, C2CH-type, IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6689 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-241b2.4, Drer\wt1a, Drer\znf408, Drer\wt1b" Scer\AZF1 "Cele\M03D4.4, Cele\Y55F3AM.14, Cele\klf-2, Cele\zfp-2, Cele\eor-1" - "Mmus\Zfp352, Mmus\Zfp810, Mmus\Klf17, Mmus\Rbak, Mmus\Zfp296, Mmus\Zfp691, Mmus\Wt1, Mmus\Klf1" "Hsap\ZNF296, Hsap\ZNF691, Hsap\ZNF560, Hsap\KLF17, Hsap\WT1, Hsap\KLF1, Hsap\ZNF281, Hsap\ZNF8" "partially lethal - majority die,some die during pupal stage" FBgn0260467 CG7071 - http://flybase.org/reports/FBgn0260467 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay "BcDNA:RE40914, CG7071, Dromel_CG7071_FBtr0084211_mORF" "IPR021013:ATPase, vacuolar ER assembly factor, Vma12" CG7071 11-Aug-17 DroID_v2017_08 Drer\tmem199 Scer\VPH2 Cele\F09E5.11 Xtro\tmem199 Mmus\Tmem199 Hsap\TMEM199 FBgn0013532 l(2)35Ab lethal (2) 35Ab http://flybase.org/reports/FBgn0013532 - gene - - - l(2)35Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038523 CG7587 - http://flybase.org/reports/FBgn0038523 protein_coding_gene - - - CG7587 - CG7587 11-Aug-17 DroID_v2017_08 - - Cele\F46F5.16 - - - viable FBgn0060939 l(3)S040428b lethal (3) S040428b http://flybase.org/reports/FBgn0060939 gene - - - "0404/28, l(3)S040428b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0032360 CG14926 - http://flybase.org/reports/FBgn0032360 protein_coding_gene - - - "bs34f02.y1, CG14926" - CG14926 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001718 l(1)ESHS39 lethal (1) ESHS39 http://flybase.org/reports/FBgn0001718 - gene - - - l(1)ESHS39 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038894 CG15497 - http://flybase.org/reports/FBgn0038894 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG15497 "IPR023393:START-like domain, IPR010562:Haemolymph juvenile hormone binding" CG15497 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032827 CG10481 - http://flybase.org/reports/FBgn0032827 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004342 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000081883 CG10481 "IPR004331:SPX domain, IPR004342:EXS, C-terminal" CG10481 11-Aug-17 DroID_v2017_08 "Drer\xpr1b, Drer\xpr1a" "Scer\SYG1, Scer\VTC3, Scer\ERD1, Scer\VTC4, Scer\VTC2" Cele\Y39A1A.22 Xtro\xpr1 Mmus\Xpr1 Hsap\XPR1 viable FBgn0037621 M1BP Motif 1 Binding Protein http://flybase.org/reports/FBgn0037621 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 RNA polymerase II core promoter sequence-specific DNA binding ; GO:0000979 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype RNA polymerase II transcriptional preinitiation complex assembly ; GO:0051123 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 "CG9797, M1BP, CC31" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG9797 11-Aug-17 DroID_v2017_08 "Drer\bcl6ab, Drer\znf408, Drer\znf770, Drer\znf341" Scer\AZF1 "Cele\M03D4.4, Cele\eor-1, Cele\ztf-23, Cele\Y55F3AM.14, Cele\blmp-1, Cele\Y37F4.6, Cele\hbl-1, Cele\klf-3" - "Mmus\Zkscan8, Mmus\Zfp341, Mmus\Zfp708, Mmus\Zfp24, Mmus\Zfp810, Mmus\Rbak, Mmus\Zfp369, Mmus\Gm13212, Mmus\Zfp945, Mmus\Zfp12, Mmus\Zfp110, Mmus\Zbtb14, Mmus\Zfp984, Mmus\Zfp93, Mmus\Zscan5b, Mmus\Zfp758, Mmus\Zfp445" "Hsap\ZNF98, Hsap\ZNF485, Hsap\ZNF784, Hsap\ZNF28, Hsap\ZNF850, Hsap\ZNF595, Hsap\ZNF558, Hsap\ZNF211, Hsap\ZNF527, Hsap\ZNF570, Hsap\ZNF816, Hsap\ZNF480, Hsap\ZSCAN30, Hsap\ZNF560, Hsap\ZNF492, Hsap\ZNF221, Hsap\ZNF284, Hsap\RBAK-RBAKDN, Hsap\ZNF341, Hsap\ZNF281, Hsap\ZNF233, Hsap\ZNF568, Hsap\ZNF845, Hsap\ZNF117, Hsap\ZNF721, Hsap\ZNF730, Hsap\ZNF121, Hsap\ZFP28, Hsap\ZNF43" FBgn0052383 sphinx1 sphinx1 http://flybase.org/reports/FBgn0052383 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred by curator from GO:0050832 "SPH194, CG8555, sphinx1, CG32383, Sphinx-1, Sphinx1" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG32383 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\LOC562139, Drer\ela3l" - - Xtro\prtn3 "Mmus\Hgf, Mmus\Klk1b3, Mmus\C1s1, Mmus\C1s2" Hsap\C1S "immune response defective,partially lethal - majority die,some die during pupal stage" FBgn0052413 CG32413 - http://flybase.org/reports/FBgn0052413 protein_coding_gene - - - "CG10487, CG32413" IPR007484:Peptidase M28 CG32413 11-Aug-17 DroID_v2017_08 "Drer\qpct, Drer\qpctla, Drer\qpctlb" Scer\YFR018C Cele\H27A22.1 "Xtro\qpctl, Xtro\qpct" "Mmus\Qpctl, Mmus\Qpct" "Hsap\QPCT, Hsap\QPCTL" viable FBgn0022699 D19B D19B http://flybase.org/reports/FBgn0022699 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 "CG10270, D19B, d19b" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10270 11-Aug-17 DroID_v2017_08 "Drer\zgc:162948, Drer\zgc:174268, Drer\znf1004, Drer\znf770, Drer\znf341, Drer\znf668" - "Cele\sdz-12, Cele\zfp-2, Cele\sem-4, Cele\spr-4, Cele\Y37F4.6, Cele\egl-43, Cele\hinf-1, Cele\Y48G8AL.10, Cele\eor-1, Cele\Y55F3AM.14, Cele\M03D4.4, Cele\lin-13" "Xtro\znf668, Xtro\zbtb41" "Mmus\Zfp112, Mmus\Zfp341, Mmus\Zfp668" "Hsap\ZNF341, Hsap\ZNF668, Hsap\ZNF30, Hsap\ZNF852, Hsap\ZNF284, Hsap\ZNF221" viable FBgn0027553 NELF-B NELF-B http://flybase.org/reports/FBgn0027553 "FBgn0029956, FBgn0052721" protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:P92204 negative regulation of transcription elongation from RNA polymerase II promoter ; GO:0034244 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter during mitosis ; GO:0007070 | inferred from sequence or structural similarity with UniProtKB:P92204 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype transcriptional repressor complex ; GO:0017053 | inferred from sequence or structural similarity with UniProtKB:P92204 NELF complex ; GO:0032021 | inferred from physical interaction with TH1 nucleus ; GO:0005634 | inferred from direct assay "CG12152, BcDNA:GH10333, NELF-B, CG32721, NELF" IPR010405:Cofactor of BRCA1 CG32721 11-Aug-17 DroID_v2017_08 Drer\nelfb - - Xtro\nelfb Mmus\Nelfb Hsap\NELFB "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0010614 l(2)06250 lethal (2) 06250 http://flybase.org/reports/FBgn0010614 - gene - - - l(2)06250 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0086040 snoRNA:Me28S-A3365 - http://flybase.org/reports/FBgn0086040 snoRNA_gene - - - "snoRNA:Me28S-A3365, Me28S-Am3365, CR34669" - CR34669 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001574 l(1)63 lethal (1) 63 http://flybase.org/reports/FBgn0001574 - gene - - - "tsl(1)63, l(1)63" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,heat sensitive,male sterile,lethal,male" "mesothoracic tarsal bristle,heat sensitive,mesothoracic tarsal bristle longitudinal row 8,mesothoracic tarsal bristle longitudinal row 1,spermatocyte,metatarsus" FBgn0023136 WppG White prepupal locus G http://flybase.org/reports/FBgn0023136 - gene - - - "35, WppG" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010767 l(3)02094 lethal (3) 02094 http://flybase.org/reports/FBgn0010767 - gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - nucleus ; GO:0005634 | inferred from sequence or structural similarity small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity "l(3)02094, L(3)02094" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086059 snoRNA:Me18S-C1280 - http://flybase.org/reports/FBgn0086059 snoRNA_gene - - - "snoRNA:Me18S-C1280, Me18S-Cm1280, CR34688" - CR34688 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036009 Or67a Odorant receptor 67a http://flybase.org/reports/FBgn0036009 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from physical interaction with Orco detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from direct assay "67a, DOR84, 67B.1, CG12526, Or67a, DmOR67a" "IPR004117:Olfactory receptor, insect" CG12526 11-Aug-17 DroID_v2017_08 - - Cele\T11F8.1 - - - viable FBgn0003397 sho shovel http://flybase.org/reports/FBgn0003397 - gene - - - sho - - 11-Aug-17 DroID_v2017_08 - - - - - - viable wing FBgn0020576 anon-59Ci anon-59Ci http://flybase.org/reports/FBgn0020576 - gene - - - anon-59Ci - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267315 lncRNA:TS16 long noncoding RNA: testis-specific 16 http://flybase.org/reports/FBgn0267315 non_protein_coding_gene - - - "lncRNA:TS16, CR45751" - CR45751 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002684 mat(3)3 maternal lethal 3 http://flybase.org/reports/FBgn0002684 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mat(3)3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,heat sensitive,some die during embryonic stage" "pole cell,heat sensitive,stage 5 embryo,dorsal,posterior,embryonic ventral nervous system" FBgn0038200 CG9920 - http://flybase.org/reports/FBgn0038200 protein_coding_gene metal ion binding ; GO:0046872 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 chaperone mediated protein folding requiring cofactor ; GO:0051085 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 response to unfolded protein ; GO:0006986 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000080669 "CG9920, BEST:GH20473, anon-WO0140519.48" "IPR011032:GroES-like, IPR020818:GroES chaperonin family" CG9920 11-Aug-17 DroID_v2017_08 Drer\hspe1 Scer\HSP10 Cele\Y22D7AL.10 Xtro\hspe1 Mmus\Hspe1 Hsap\HSPE1 "viable,visible" trichogen cell FBgn0037014 CG13251 - http://flybase.org/reports/FBgn0037014 protein_coding_gene - - - CG13251 - CG13251 11-Aug-17 DroID_v2017_08 Drer\ccdc66 - - - Mmus\Ccdc66 Hsap\CCDC66 viable FBgn0004473 ant antennaless http://flybase.org/reports/FBgn0004473 - gene - - - ant - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" antenna FBgn0032446 CG5780 - http://flybase.org/reports/FBgn0032446 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:29669 intraciliary retrograde transport ; GO:0035721 | inferred from sequence or structural similarity with HGNC:29669 intraciliary transport particle A ; GO:0030991 | inferred from sequence or structural similarity with HGNC:29669 "CG5780, IFT43" IPR029302:Intraflagellar transport protein 43 CG5780 11-Aug-17 DroID_v2017_08 Drer\ift43 - - Xtro\ift43 Mmus\Ift43 Hsap\IFT43 FBgn0001875 l(1)XN82a lethal (1) XN82a http://flybase.org/reports/FBgn0001875 - gene - - - l(1)XN82a - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015314 Tahiti Tahiti http://flybase.org/reports/FBgn0015314 - region - - - Tahiti - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004380 Klp64D Kinesin-like protein at 64D http://flybase.org/reports/FBgn0004380 - protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" sensory perception of smell ; GO:0007608 | inferred from mutant phenotype anterograde axonal transport ; GO:0008089 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with arm inferred from genetic interaction with dsh inferred from genetic interaction with wg inferred from physical interaction with arm inferred from physical interaction with dsh sensory perception of sound ; GO:0007605 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | NOT inferred from mutant phenotype cell junction ; GO:0030054 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 cilium ; GO:0005929 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "Kif3A, klp64D, CG10642, DmKlp64D, KLP64D, KLP4, Klp4, Klp64D, KLP64Ddm, Klp 64D, KIF 3A, KIF3A, kif3A" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10642 11-Aug-17 DroID_v2017_08 "Drer\kif17, Drer\kif5bb, Drer\kif3b, Drer\kif11, Drer\kif3a, Drer\kif5ba, Drer\LOC100331925, Drer\kif5c, Drer\kif5ab, Drer\kif3cb" "Scer\SMY1, Scer\KIP1, Scer\CIN8, Scer\KIP3" "Cele\klp-20, Cele\osm-3, Cele\bmk-1, Cele\klp-11" "Xtro\kif5c, Xtro\kif3a, Xtro\kif3b, Xtro\kif5a, Xtro\kif3c, Xtro\kif5b" "Mmus\Kif5a, Mmus\Kif3a, Mmus\Kif5b, Mmus\Kif5c, Mmus\Kif11, Mmus\Kif3b, Mmus\Kif17, Mmus\Kif3c, Mmus\Gm1305" "Hsap\KIF3A, Hsap\KIF3C, Hsap\KIF5A, Hsap\KIF5C, Hsap\KIF11, Hsap\KIF3B, Hsap\KIF5B" " adult stage , adult stage | female " " head

, ovary

" "lethal,recessive,hypoactive,uncoordinated,neuroanatomy defective,neurophysiology defective,auditory perception defective,female,viable" "scolopidial cilium,Johnston's organ & scolopidial cilium,cilium & cell,sensillum basiconicum of antennal segment 3,sensillum trichodeum of antennal segment 3,cilium,Johnston organ,scolopidial cilium & Johnston's organ,axonelav.PLu" FBgn0266864 CR45325 - http://flybase.org/reports/FBgn0266864 non_protein_coding_gene - - - CR45325 - CR45325 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039461 CG5500 - http://flybase.org/reports/FBgn0039461 protein_coding_gene - - - CG5500 "IPR019180:Oxidoreductase-like, N-terminal" CG5500 11-Aug-17 DroID_v2017_08 Drer\oxld1 Scer\YPL107W Cele\C49A9.10 - Mmus\Oxld1 Hsap\OXLD1 "fertile,viable,partially lethal - majority die,some die during pupal stage" FBgn0001834 l(1)ts538 lethal (1) ts538 http://flybase.org/reports/FBgn0001834 - gene - - - l(1)ts538 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0011950 tRNA:Arg-TCG-3-3 transfer RNA:Arginine-TCG 3-3 http://flybase.org/reports/FBgn0011950 "FBgn0011947, FBgn0052619, FBgn0060080" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna6-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-d, CR32619, tRNA:arg12Ec, chrX.trna10-ArgTCG, tRNA-Arg-TCG-3-3, tRNA:Arg-TCG-3-3, tRNA:R:12Ec, CGA" - CR32619 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267207 CR45647 - http://flybase.org/reports/FBgn0267207 non_protein_coding_gene - - - CR45647 - CR45647 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259519 GG01518 - http://flybase.org/reports/FBgn0259519 gene - - - GG01518 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033234 MFS12 Major Facilitator Superfamily Transporter 12 http://flybase.org/reports/FBgn0033234 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "anon-WO0140519.99, CG8791, MFS12" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8791 11-Aug-17 DroID_v2017_08 "Drer\slc17a9a, Drer\si:ch1073-513e17.1, Drer\ppt1, Drer\slc17a6b, Drer\slc17a8, Drer\slc17a6a, Drer\slc17a7a, Drer\slc17a5" "Scer\THI73, Scer\VHT1, Scer\YIL166C, Scer\DAL5, Scer\FEN2, Scer\YCT1, Scer\TNA1" "Cele\T22F3.10, Cele\vglu-3, Cele\F56A4.12, Cele\C01B4.8, Cele\Y15E3A.4, Cele\Y19D10A.11, Cele\D1046.4, Cele\C18D1.2, Cele\T22F3.8, Cele\Y19D10A.5, Cele\eat-4, Cele\T27D12.1, Cele\F44E7.7, Cele\slc-17.2, Cele\K11G9.5, Cele\M162.5, Cele\W04C9.6, Cele\slc-17.8, Cele\Y4C6B.3, Cele\slc-17.9, Cele\F41C3.2, Cele\T19D12.9, Cele\T02B11.6, Cele\Y19D10A.8, Cele\Y19D10A.4, Cele\Y51B9A.6, Cele\H11E01.2, Cele\C35A5.3, Cele\F11A5.9, Cele\T28H11.8, Cele\F59A1.13, Cele\C18H9.5, Cele\F56A4.10, Cele\slc-17.3, Cele\cima-1, Cele\Y4C6B.4, Cele\C39E9.7, Cele\F10C2.7, Cele\M117.1, Cele\T01H3.3, Cele\slc-17.5, Cele\K08C7.1, Cele\T22F3.7, Cele\vglu-2, Cele\C01B4.7, Cele\T19D12.10, Cele\slc-17.1, Cele\R10D12.1, Cele\slc-17.4, Cele\T22F3.11" Xtro\slc17a7 "Mmus\Slc17a7, Mmus\Slc17a4, Mmus\Slc17a1, Mmus\Slc17a6, Mmus\Slc17a2, Mmus\Slc17a3, Mmus\Slc17a5, Mmus\Slc17a8" "Hsap\SLC17A4, Hsap\SLC17A8, Hsap\SLC17A5, Hsap\SLC17A2, Hsap\SLC17A6, Hsap\SLC17A7, Hsap\SLC17A1, Hsap\SLC17A3" "viable,fertile" FBgn0040919 CG15895 - http://flybase.org/reports/FBgn0040919 protein_coding_gene - - - CG15895 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036032 CG16711 - http://flybase.org/reports/FBgn0036032 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG16711 IPR015943:WD40/YVTN repeat-like-containing domain CG16711 11-Aug-17 DroID_v2017_08 Drer\brd4 - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0069052 COM centre organisateur de mobilisation http://flybase.org/reports/FBgn0069052 gene - - - COM - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003168 Pur-r Purine-resistant http://flybase.org/reports/FBgn0003168 - gene - - - "PurR, Pur-r" - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0017363 l(3)89Bq lethal (3) 89Bq http://flybase.org/reports/FBgn0017363 - gene - - - "l(3)89Bo, l(3)89Bq" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005149 l(2)G78 lethal (2) G78 http://flybase.org/reports/FBgn0005149 - gene - - - l(2)G78 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034961 CG3163 - http://flybase.org/reports/FBgn0034961 protein_coding_gene - - - CG3163 IPR006578:MADF domain CG3163 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033029 Not3 CCR4-NOT transcription complex subunit 3 http://flybase.org/reports/FBgn0033029 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 poly(A)-specific ribonuclease activity ; GO:0004535 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR007207, InterPro:IPR007282, InterPro:IPR012270 mRNA catabolic process ; GO:0006402 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR007207, InterPro:IPR007282, InterPro:IPR012270 CCR4-NOT complex ; GO:0030014 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000595684" "Not3, NOT3, CG8426, NOT3/5, l(2)NC136, CNOT3, NOT3.5, not3" "IPR007207:CCR4-Not complex component, Not N-terminal domain, IPR007282:NOT2/NOT3/NOT5, IPR012270:CCR4-NOT complex, subunit 3/ 5" CG8426 11-Aug-17 DroID_v2017_08 "Drer\cnot3a, Drer\cnot3b" "Scer\NOT3, Scer\NOT5" Cele\ntl-3 Xtro\cnot3 Mmus\Cnot3 Hsap\CNOT3 "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC04908 IE -0.439208659 -4.097402297 -2.378796068 -1.774960794 0.082698651 -0.643598999 FBgn0011971 tRNA:Ser-GCT-2-2 transfer RNA:Serine-GCT 2-2 http://flybase.org/reports/FBgn0011971 "FBgn0011968, FBgn0011969, FBgn0051476, FBgn0060055" tRNA_gene AGC codon-amino acid adaptor activity ; GO:0033446 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033446 cytosol ; GO:0005829 | inferred by curator from GO:0033446 "CR31476, tRNA[Ser][[2b]], AE002708.trna53-SerGCT, tRNA:S:GCT:AE002708-e, tRNA:ser, tRNA:S, tRNA:ser2b, tRNA:S2b, tRNA:ser2b:88A, tRNA[[Ser]], chr3R.trna59-SerGCT, tRNA-Ser-GCT-2-2, tRNA:Ser-GCT-2-2, tRNA:S2b:88A, AGC" - CR31476 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085829 CR42196 - http://flybase.org/reports/FBgn0085829 non_protein_coding_gene - - - CR42196 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001427 l(1)6Ed lethal (1) 6Ed http://flybase.org/reports/FBgn0001427 - gene - - - "l(1)jnL2, JNL2, jnL2, l(1)6Ed" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0014073 Tie Tie-like receptor tyrosine kinase http://flybase.org/reports/FBgn0014073 - protein_coding_gene "protein tyrosine kinase activity ; GO:0004713 | inferred from electronic annotation with InterPro:IPR020635 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity" protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from sequence or structural similarity with HGNC:11724 border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Egfr inferred from genetic interaction with Pvr negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from sequence or structural similarity with HGNC:11724 regulation of cellular response to X-ray ; GO:2000683 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:11724 "tie, RTK, CG7525, DPR1, Tie" "IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG7525 11-Aug-17 DroID_v2017_08 "Drer\fgfr1a, Drer\si:ch73-206d17.1, Drer\tek, Drer\fgfr2, Drer\mylk4a, Drer\flt1, Drer\csf1ra, Drer\mertka, Drer\fgfr3, Drer\tie1, Drer\kdrl, Drer\pdgfrl, Drer\si:dkey-14o18.6, Drer\ret, Drer\kita, Drer\mylkb, Drer\flt4, Drer\pdgfrb, Drer\csf1rb, Drer\LOC569566, Drer\kdr, Drer\mylk5, Drer\si:ch211-167j9.5, Drer\tyro3, Drer\pdgfra, Drer\kitb, Drer\fgfrl1a, Drer\flt3, Drer\fgfr4, Drer\styk1, Drer\fgfrl1b" - "Cele\Y38H6C.20, Cele\T25B9.4" "Xtro\fgfrl1, Xtro\pdgfrl, Xtro\styk1, Xtro\csf1r, Xtro\fgfr1, Xtro\tie1, Xtro\flt1, Xtro\tek, Xtro\kdr, Xtro\fgfr4, Xtro\ret, Xtro\pdgfrl.2, Xtro\pdgfra, Xtro\fgfr2, Xtro\flt4, Xtro\fgfr3" "Mmus\Kdr, Mmus\Ret, Mmus\Flt1, Mmus\Fgfr2, Mmus\Fgfr1, Mmus\Flt4, Mmus\Pdgfrb, Mmus\Pdgfra, Mmus\Tyro3, Mmus\Lmtk3, Mmus\Flt3, Mmus\Tie1, Mmus\Tek, Mmus\Styk1, Mmus\Fgfrl1, Mmus\Pdgfrl, Mmus\Kit, Mmus\Mertk, Mmus\Csf1r, Mmus\Fgfr3, Mmus\Fgfr4, Mmus\Axl" "Hsap\FGFR2, Hsap\FLT4, Hsap\FLT1, Hsap\TYRO3, Hsap\FLT3, Hsap\RET, Hsap\AXL, Hsap\PDGFRA, Hsap\KDR, Hsap\PDGFRB, Hsap\KIT, Hsap\TIE1, Hsap\TEK, Hsap\CSF1R, Hsap\FGFR4, Hsap\MERTK, Hsap\LMTK3, Hsap\PDGFRL, Hsap\STYK1, Hsap\FGFR1, Hsap\FGFR3, Hsap\FGFRL1" "viable,radiation sensitive,dominant" DRSC08702 I 1.634500123 0.021945634 1.240433087 -0.259324327 -0.153639017 -0.926267686 FBgn0260484 HIP Hsc/Hsp70-interacting protein http://flybase.org/reports/FBgn0260484 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR034649 heat shock protein binding ; GO:0031072 | inferred from sequence or structural similarity with UniProtKB:P50503 Hsp70 protein binding ; GO:0030544 | inferred from sequence or structural similarity with UniProtKB:P50503 chaperone binding ; GO:0051087 | inferred from sequence or structural similarity with UniProtKB:P50503 chaperone cofactor-dependent protein refolding ; GO:0070389 | inferred from sequence or structural similarity with UniProtKB:P50503 protein complex ; GO:0043234 | inferred from sequence or structural similarity with UniProtKB:P50503 cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P50503 "anon-EST:fe1A9, HIP, CG32789" "IPR011990:Tetratricopeptide-like helical domain, IPR006636:Heat shock chaperonin-binding, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR034649:Hsp70-interacting protein, N-terminal" CG32789 11-Aug-17 DroID_v2017_08 Drer\st13 Scer\SGT1 Cele\hip-1 Xtro\st13 "Mmus\St13, Mmus\Ppp5c" Hsap\ST13 FBgn0065953 l(2)SH0067 lethal (2) SH0067 http://flybase.org/reports/FBgn0065953 gene - - - "l(2)SH0067, l(2)SH2 0067" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004818 fs(2)ltoDC37 female sterile (2) ltoDC37 http://flybase.org/reports/FBgn0004818 - gene molecular_function ; GO:0003674 | no biological data available ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoDC37 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0013769 CypB Cyclophylin B http://flybase.org/reports/FBgn0013769 - gene - - - "DCyp-B, CypB" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040551 CG11686 - http://flybase.org/reports/FBgn0040551 protein_coding_gene - - - "BcDNA:RH19248, CG11686" - CG11686 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0065170 l(3)SH026 lethal (3) SH026 http://flybase.org/reports/FBgn0065170 gene - - - "l(3)SH026, l(2)SH3 026" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263051 CG43346 - http://flybase.org/reports/FBgn0263051 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR007763 electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR007763 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR007763 cellular_component ; GO:0005575 | no biological data available "CG43346, CG9243" IPR007763:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 CG43346 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-110e4.6, Drer\ndufaf2, Drer\pld3, Drer\si:ch211-194e18.2" - "Cele\F09G2.8, Cele\Y116A8C.30, Cele\E04F6.4" Xtro\pld3 "Mmus\Pld4, Mmus\Pld3, Mmus\Ndufaf2, Mmus\Pld5" "Hsap\PLD3, Hsap\PLD5, Hsap\PLD4, Hsap\NDUFAF2" embryonic/larval hemocyte | third instar larval stage FBgn0000771 fs(1)A1140 female sterile (1) A1140 http://flybase.org/reports/FBgn0000771 - gene - - - "fs(1)1140, fs(1)A1140" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,mitotic cell cycle defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" "blastoderm embryo,gastrula embryo" FBgn0265069 CR44180 - http://flybase.org/reports/FBgn0265069 non_protein_coding_gene - - - CR44180 - CR44180 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065218 l(2)SH2238 lethal (2) SH2238 http://flybase.org/reports/FBgn0065218 gene - - - "l(2)SH2238, l(2)SH2 2238" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052033 CG32033 - http://flybase.org/reports/FBgn0052033 protein_coding_gene - - - CG32033 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060528 l(3)S101710 lethal (3) S101710 http://flybase.org/reports/FBgn0060528 gene - - - "1017/10, l(3)S101710" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0085808 CR41591 - http://flybase.org/reports/FBgn0085808 rRNA_gene - - - CR41591 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014050 Su(tor)2-28 Su(tor)2-28 http://flybase.org/reports/FBgn0014050 - gene - - - Su(tor)2-28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0032464 Vha68-3 Vacuolar H[+] ATPase 68kD subunit 3 http://flybase.org/reports/FBgn0032464 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000389800 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033176" "ATP metabolic process ; GO:0046034 | inferred from electronic annotation with InterPro:IPR004100, InterPro:IPR022878 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000793, InterPro:IPR005725 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033176" "proton-transporting V-type ATPase, V1 domain ; GO:0033180 | inferred from electronic annotation with InterPro:IPR005725 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000389800 lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN001032512 proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity with Vha68-2" "vha68-3, CG5075, Vha68-3, Vha68, vha67-3" "IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005725:ATPase, V1 complex, subunit A, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024034:ATPase, F1/V1 complex, beta/alpha subunit, C-terminal, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR022878:V-type ATP synthase catalytic alpha chain, IPR031686:ATPsynthase alpha/beta subunit, N-terminal extension" CG5075 11-Aug-17 DroID_v2017_08 "Drer\atp6v1ab, Drer\atp6v1aa" Scer\VMA1 Cele\vha-13 Xtro\atp6v1a Mmus\Atp6v1a Hsap\ATP6V1A viable FBgn0028617 l(2)35Ch lethal (2) 35Ch http://flybase.org/reports/FBgn0028617 gene - - - l(2)35Ch - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033018 CG10453 - http://flybase.org/reports/FBgn0033018 protein_coding_gene - - - CG10453 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069298 amfos amigo de fos http://flybase.org/reports/FBgn0069298 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available amfos - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020356 anon-2Da anon-2Da http://flybase.org/reports/FBgn0020356 - gene - - - "2D3, anon-2Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053284 CG33284 - http://flybase.org/reports/FBgn0053284 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs10b10, CG33284" - CG33284 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033484 CG2269 - http://flybase.org/reports/FBgn0033484 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.141, CG2269" - CG2269 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264633 bulgy bulgy http://flybase.org/reports/FBgn0264633 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - bulgy - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0040782 CG12827 - http://flybase.org/reports/FBgn0040782 protein_coding_gene - - - CG12827 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039597 CG9997 - http://flybase.org/reports/FBgn0039597 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern protein localization ; GO:0008104 | inferred from mutant phenotype regulation of female receptivity, post-mating ; GO:0046008 | inferred from mutant phenotype sperm competition ; GO:0046692 | inferred from direct assay" extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model CG9997 "IPR009003:Peptidase S1, PA clan, IPR001254:Serine proteases, trypsin domain" CG9997 11-Aug-17 DroID_v2017_08 - - - - - Hsap\TMPRSS11B "mating rhythm defective,viable" FBgn0265166 CR44235 - http://flybase.org/reports/FBgn0265166 non_protein_coding_gene - - - CR44235 - CR44235 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013316 Pcp15 Pupal-cuticle-protein-15kD http://flybase.org/reports/FBgn0013316 - gene - - - Pcp15 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034940 CG16787 - http://flybase.org/reports/FBgn0034940 protein_coding_gene - - - CG16787 IPR018790:Protein of unknown function DUF2358 CG16787 11-Aug-17 DroID_v2017_08 Drer\si:ch211-215a10.4 - "Cele\Y48E1C.4, Cele\C27B7.2" Xtro\c6orf136 Mmus\2310061I04Rik Hsap\C6orf136 "lethal - all die before end of pupal stage,some die during pupal stage,lethal,body color defective" mesothoracic tergum FBgn0060394 l(3)S132802b lethal (3) S132802b http://flybase.org/reports/FBgn0060394 gene - - - "1328/02, l(3)S132802b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034443 cer crammer http://flybase.org/reports/FBgn0034443 protein_coding_gene cysteine-type peptidase activity ; GO:0008234 | inferred from electronic annotation with InterPro:IPR013128 cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from direct assay short-term memory ; GO:0007614 | inferred from direct assay inhibition of cysteine-type endopeptidase activity ; GO:0097340 | inferred from direct assay long-term memory ; GO:0007616 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay lysosome ; GO:0005764 | inferred from sequence model "CG10460, cer, D/CTLA-2, CER" "IPR013201:Cathepsin propeptide inhibitor domain (I29), IPR013128:Peptidase C1A" CG10460 11-Aug-17 DroID_v2017_08 "Drer\ctsc, Drer\ctss1, Drer\si:dkey-239j18.3, Drer\si:dkey-239j18.2, Drer\LOC100536033, Drer\ctsll, Drer\si:dkey-269i1.3, Drer\ctsbb, Drer\ctsba, Drer\ctslb, Drer\wu:fa26c03, Drer\MGC174155, Drer\si:dkey-26g8.4, Drer\LOC100333521, Drer\si:dkey-269i1.4, Drer\cts12, Drer\ctsz, Drer\si:dkey-183k8.2, Drer\ctss2.1, Drer\ctsl.1, Drer\ctsh, Drer\zgc:110239, Drer\zgc:174855, Drer\si:dkey-228a15.1, Drer\si:dkey-267n13.1, Drer\ctss2.2, Drer\zgc:174153, Drer\ctsk, Drer\ctsla, Drer\zgc:103438, Drer\MGC174857" - Cele\cpl-1 "Xtro\ctsc, Xtro\ctsl, Xtro\LOC100498238, Xtro\LOC100490139, Xtro\ctsh, Xtro\ctss, Xtro\ctsz, Xtro\ctsv, Xtro\ctsb" "Mmus\Ctss, Mmus\BC051665, Mmus\Cts6, Mmus\4930486L24Rik, Mmus\Ctsll3, Mmus\Ctsq, Mmus\Cts8, Mmus\Ctsm, Mmus\Ctla2b, Mmus\Ctsh, Mmus\Ctla2a, Mmus\Ctsj, Mmus\Ctsl, Mmus\Ctsz, Mmus\Ctsr, Mmus\Cts7, Mmus\Ctsk, Mmus\Ctsc, Mmus\Cts3, Mmus\Ctsb" "Hsap\CTSH, Hsap\CTSL, Hsap\CTSV, Hsap\CTSS, Hsap\CTSZ, Hsap\CTSC, Hsap\CTSB, Hsap\CTSK" "memory defective,recessive,feeding behavior defective,viable" FBgn0032280 CG17105 - http://flybase.org/reports/FBgn0032280 protein_coding_gene - - - CG17105 - CG17105 11-Aug-17 DroID_v2017_08 - - Cele\nlp-24 - - - viable FBgn0062654 EP3621 EP3621 http://flybase.org/reports/FBgn0062654 gene - - - "EP(3)3621, EP3621" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040674 CG9445 - http://flybase.org/reports/FBgn0040674 protein_coding_gene - mesoderm development ; GO:0007498 | inferred from expression pattern - CG9445 - CG9445 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065151 l(3)SH066 lethal (3) SH066 http://flybase.org/reports/FBgn0065151 gene - - - "l(3)SH066, l(2)SH3 066" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263129 Cbl::drk Cbl::drk http://flybase.org/reports/FBgn0263129 engineered_fusion_gene - - - Cbl::drk - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034352 CG17669 - http://flybase.org/reports/FBgn0034352 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17669 "IPR027974:Domain of unknown function DUF4470, IPR028235:Dynein assembly factor 3, C-terminal domain" CG17669 11-Aug-17 DroID_v2017_08 "Drer\dnaaf3l, Drer\dnaaf3" - - Xtro\dnaaf3 Mmus\Dnaaf3 Hsap\DNAAF3 viable FBgn0085690 CG41559 - http://flybase.org/reports/FBgn0085690 protein_coding_gene - - - CG41559 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067856 Theseus Theseus http://flybase.org/reports/FBgn0067856 gene G-protein coupled receptor activity ; GO:0004930 | non-traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | non-traceable author statement germ cell migration ; GO:0008354 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred by curator from GO:0004930 "theseus, Theseus" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259969 Sfp65A Seminal fluid protein 65A http://flybase.org/reports/FBgn0259969 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp65A, CG42479" - CG42479 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086383 BG01533 - http://flybase.org/reports/FBgn0086383 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01533 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0053109 CG33109 - http://flybase.org/reports/FBgn0053109 protein_coding_gene - - - "CG9645, CG33109, cg9645" - CG33109 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022095 l(2)k07219 lethal (2) k07219 http://flybase.org/reports/FBgn0022095 - gene - - - l(2)k07219 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037330 mRpL44 mitochondrial ribosomal protein L44 http://flybase.org/reports/FBgn0037330 protein_coding_gene ribonuclease III activity ; GO:0004525 | inferred from electronic annotation with InterPro:IPR000999 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9H9J2 RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR000999 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9H9J2 "MRP-L44, CG2109, mRpL44" IPR000999:Ribonuclease III domain CG2109 11-Aug-17 DroID_v2017_08 Drer\mrpl44 Scer\MRPL3 Cele\F02A9.4 Xtro\mrpl44 Mmus\Mrpl44 Hsap\MRPL44 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0033971 CG10209 - http://flybase.org/reports/FBgn0033971 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 apoptotic process ; GO:0006915 | inferred from electronic annotation with InterPro:IPR026753 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026753 CG10209 "IPR004210:BESS motif, IPR026753:Nuclear apoptosis-inducing factor 1, IPR028002:Myb/SANT-like DNA-binding domain" CG10209 11-Aug-17 DroID_v2017_08 "Drer\zgc:153990, Drer\zgc:113149, Drer\si:ch211-261d7.3, Drer\naif1" - - - Mmus\Naif1 Hsap\NAIF1 lethal FBgn0264265 CR43765 - http://flybase.org/reports/FBgn0264265 non_protein_coding_gene - - - "CR43765, lincRNA.231" - CR43765 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017577 Mcm5 Minichromosome maintenance 5 http://flybase.org/reports/FBgn0017577 - protein_coding_gene "chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR008048 DNA replication origin binding ; GO:0003688 | inferred from electronic annotation with InterPro:IPR008048 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008048, InterPro:IPR018525 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR008048 DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype resolution of meiotic recombination intermediates ; GO:0000712 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008048 MCM complex ; GO:0042555 | inferred from electronic annotation with InterPro:IPR008048 "MCM5, mcm5, CG4082, DmMcm5, DmMCM5, PCR4, DmCDC465, DmCDC46, Mcm5, McM5, DmeMCM5" "IPR018525:Mini-chromosome maintenance, conserved site, IPR001208:MCM domain, IPR008048:DNA replication licensing factor Mcm, IPR012340:Nucleic acid-binding, OB-fold, IPR033762:MCM OB domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027925:MCM N-terminal domain, IPR031327:Mini-chromosome maintenance protein" CG4082 11-Aug-17 DroID_v2017_08 Drer\mcm5 Scer\MCM5 Cele\mcm-5 Xtro\mcm5 Mmus\Mcm5 Hsap\MCM5 "viable,meiotic cell cycle defective,fertile,lethal,recessive,visible" "nuclear chromosome,imaginal disc,trichogen cell" FBgn0267694 CR46030 - http://flybase.org/reports/FBgn0267694 non_protein_coding_gene - - - CR46030 - CR46030 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034356 CG10924 - http://flybase.org/reports/FBgn0034356 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR008209 phosphoenolpyruvate carboxykinase (GTP) activity ; GO:0004613 | inferred from sequence or structural similarity with UniProtKB:Q16822 gluconeogenesis ; GO:0006094 | inferred from sequence or structural similarity with UniProtKB:Q16822 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q16822 "CG10924, PEPCK, pepck2" "IPR008209:Phosphoenolpyruvate carboxykinase, GTP-utilising, IPR018091:Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site, IPR013035:Phosphoenolpyruvate carboxykinase, C-terminal, IPR008210:Phosphoenolpyruvate carboxykinase, N-terminal" CG10924 11-Aug-17 DroID_v2017_08 "Drer\pck2, Drer\pck1" - "Cele\pck-1, Cele\pck-2, Cele\pck-3" "Xtro\pck1, Xtro\pck2" "Mmus\Pck1, Mmus\Pck2" "Hsap\PCK1, Hsap\PCK2" "viable,fertile" FBgn0002176 l(3)7E103 lethal (3) 7E103 http://flybase.org/reports/FBgn0002176 - gene - - - l(3)7E103 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265401 EP902 - http://flybase.org/reports/FBgn0265401 gene - - - EP902 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011622 l(2)10610 lethal (2) 10610 http://flybase.org/reports/FBgn0011622 - gene - - - l(2)10610 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053246 Ste:CG33246 Ste:CG33246 http://flybase.org/reports/FBgn0053246 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay "CG32605, CG33246, Ste:CG33246" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33246 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0014877 Roe1 Roe1 http://flybase.org/reports/FBgn0014877 FBgn0064950 protein_coding_gene chaperone binding ; GO:0051087 | inferred from electronic annotation with InterPro:IPR000740 protein homodimerization activity ; GO:0042803 | inferred from electronic annotation with InterPro:IPR000740 adenyl-nucleotide exchange factor activity ; GO:0000774 | inferred from biological aspect of ancestor with PANTHER:PTN000478264 unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:Q8TAA5 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000478264 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000478265 protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:Q8TAA5 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q8TAA5 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q8TAA5 presequence translocase-associated import motor ; GO:0001405 | inferred from biological aspect of ancestor with PANTHER:PTN000478265 "DROE1, droe1, BcDNA:GM03203, Droe1, CG6155, Roe1, cg6155" "IPR000740:GrpE nucleotide exchange factor, IPR009012:GrpE nucleotide exchange factor, head, IPR013805:GrpE nucleotide exchange factor, coiled-coil" CG6155 11-Aug-17 DroID_v2017_08 "Drer\grpel1, Drer\grpel2" Scer\MGE1 Cele\C34C12.8 "Xtro\grpel1, Xtro\grpel2" "Mmus\Grpel2, Mmus\Grpel1" "Hsap\GRPEL2, Hsap\GRPEL1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0061012 l(3)S026111 lethal (3) S026111 http://flybase.org/reports/FBgn0061012 gene - - - "0261/11, l(3)S026111" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0005176 l(2)Stn lethal of Steinmetz http://flybase.org/reports/FBgn0005176 - gene - - - l(2)Stn - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "eye,cuticle" FBgn0010190 tu-54e tu-54e http://flybase.org/reports/FBgn0010190 - gene - - - tu-54e - - 11-Aug-17 DroID_v2017_08 - - - - - - melanotic mass phenotype FBgn0037646 CAHbeta Carbonic anhydrase beta http://flybase.org/reports/FBgn0037646 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001765 zinc ion binding ; GO:0008270 | inferred from sequence model carbonate dehydratase activity ; GO:0004089 | inferred from direct assay one-carbon metabolic process ; GO:0006730 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "DmBCA, CG11967, CAHbeta, Dmel_CG11967, beta-CA" IPR001765:Carbonic anhydrase CG11967 11-Aug-17 DroID_v2017_08 - Scer\NCE103 "Cele\bca-2, Cele\bca-1" - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0051784 CG31784 - http://flybase.org/reports/FBgn0051784 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs05c10, CG31784" IPR025254:Domain of unknown function DUF4201 CG31784 11-Aug-17 DroID_v2017_08 Drer\ccdc96 Scer\SLK19 Cele\T11B7.1 - "Mmus\Ccdc96, Mmus\Spn" "Hsap\SPN, Hsap\CCDC96" "viable,fertile,visible" mesothoracic tergum FBgn0069178 mcl(2)Z3384 mcl(2)Z3384 http://flybase.org/reports/FBgn0069178 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z3384 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0036414 nan nanchung http://flybase.org/reports/FBgn0036414 protein_coding_gene cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with pyx calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000832860 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype response to humidity ; GO:0009270 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from sequence or structural similarity with pyx detection of mechanical stimulus involved in sensory perception ; GO:0050974 | inferred from mutant phenotype response to auditory stimulus ; GO:0010996 | inferred from direct assay startle response ; GO:0001964 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception of touch ; GO:0050976 | inferred from mutant phenotype neuromuscular process controlling posture ; GO:0050884 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity adult walking behavior ; GO:0007628 | inferred from mutant phenotype negative gravitaxis ; GO:0048060 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000061616 cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with pyx "TRPV, OCR, CT18317, CG5842, nan, Nan, DmNan, NAN" "IPR002110:Ankyrin repeat, IPR005821:Ion transport domain, IPR020683:Ankyrin repeat-containing domain, IPR024862:Transient receptor potential cation channel subfamily V" CG5842 11-Aug-17 DroID_v2017_08 "Drer\trpv4, Drer\trpv1, Drer\trpv6" Scer\YVC1 "Cele\ocr-2, Cele\ocr-1, Cele\ocr-3, Cele\ocr-4" "Xtro\trpv3, Xtro\trpv2, Xtro\trpv4, Xtro\trpv1" "Mmus\Trpv5, Mmus\Trpv4, Mmus\Trpv6, Mmus\Trpv3, Mmus\Trpv2, Mmus\Trpv1" "Hsap\TRPV6, Hsap\TRPV5, Hsap\TRPV1, Hsap\TRPV2, Hsap\TRPV3, Hsap\TRPV4" "courtship behavior defective,recessive,viable,uncoordinated,auditory perception defective,neurophysiology defective,behavior defective,locomotor behavior defective,gravitaxis defective,lethal" Johnston organ neuron FBgn0029058 l(1)G0435 lethal (1) G0435 http://flybase.org/reports/FBgn0029058 gene - - - l(1)G0435 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263467 snoRNA:nop5-x16-a - http://flybase.org/reports/FBgn0263467 snoRNA_gene - - - "snoRNA:nop5-x16-a, snoRNA:nop_x16-a, snoCD_05" - CR43582 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082926 snoRNA:Me28S-U1848 snoRNA:Me28S-U1848 http://flybase.org/reports/FBgn0082926 snoRNA_gene - - - "snoRNA:Me28S-U1848, Me28S-Um1848, Me28s-U1848, CR34535" - CR34535 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001422 l(1)6Df lethal (1) 6Df http://flybase.org/reports/FBgn0001422 - gene - - - l(1)6Df - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0267557 CR45897 - http://flybase.org/reports/FBgn0267557 non_protein_coding_gene - - - CR45897 - CR45897 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025628 CG4199 - http://flybase.org/reports/FBgn0025628 - protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR017941 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR016156 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR016156, InterPro:IPR017941, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR004099, InterPro:IPR016156, InterPro:IPR017941, InterPro:IPR023753" - "CG4199, 143005_at, EG:22E5.5" "IPR023753:FAD/NAD(P)-binding domain, IPR016156:FAD/NAD-linked reductase, dimerisation domain, IPR017941:Rieske [2Fe-2S] iron-sulphur domain" CG4199 11-Aug-17 DroID_v2017_08 "Drer\aifm4, Drer\aifm2, Drer\aifm3, Drer\aifm5" Scer\AIF1 Cele\F20D6.11 "Xtro\aifm3, Xtro\aifm2, Xtro\LOC100498581" Mmus\Aifm3 Hsap\AIFM3 "viable,fertile" FBgn0003991 vss variable size and shape http://flybase.org/reports/FBgn0003991 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "vss-1, vss" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,maternal effect" egg FBgn0067734 l(1)G0463 lethal (1) G0463 http://flybase.org/reports/FBgn0067734 gene - - - l(1)G0463 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0262068 EG56 - http://flybase.org/reports/FBgn0262068 gene - - - EG56 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266829 CR45291 - http://flybase.org/reports/FBgn0266829 non_protein_coding_gene - - - CR45291 - CR45291 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082942 snoRNA:Me28S-A982b snoRNA:Me28S-A982b http://flybase.org/reports/FBgn0082942 snoRNA_gene - - - "snoRNA:Me28S-A982b, Me28S-Am982b, CR34528, DmSnR39/59b" - CR34528 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030066 CG1885 - http://flybase.org/reports/FBgn0030066 protein_coding_gene uroporphyrinogen-III synthase activity ; GO:0004852 | inferred from biological aspect of ancestor with PANTHER:PTN000273374 uroporphyrinogen III biosynthetic process ; GO:0006780 | inferred from biological aspect of ancestor with PANTHER:PTN000273374 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000273374 - CG1885 "IPR003754:Tetrapyrrole biosynthesis, uroporphyrinogen III synthase" CG1885 11-Aug-17 DroID_v2017_08 Drer\uros Scer\HEM4 - Xtro\uros Mmus\Uros Hsap\UROS FBgn0035829 HP4 Heterochromatin protein 4 http://flybase.org/reports/FBgn0035829 protein_coding_gene - chromatin organization ; GO:0006325 | inferred from mutant phenotype "polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay nuclear heterochromatin ; GO:0005720 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay chromocenter ; GO:0010369 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay" "BcDNA:GM01628, CG8044, hip, HP4, Hip" - CG8044 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,suppressor of variegation,dominant" FBgn0051279 CG31279 - http://flybase.org/reports/FBgn0051279 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31279 - CG31279 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031053 CG14223 - http://flybase.org/reports/FBgn0031053 protein_coding_gene - - - CG14223 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR029201:Jiraiya" CG14223 11-Aug-17 DroID_v2017_08 - - - - - - DRSC24816 K -0.111555407 -0.194712974 0.089880742 -0.097187759 1.630112523 0.81189103 FBgn0283478 und uninitiated http://flybase.org/reports/FBgn0283478 protein_coding_gene aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR002468 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR002468 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR002468 - "MAP2, DMAP2, CG4008, und, p67" "IPR000994:Peptidase M24, IPR001714:Peptidase M24, methionine aminopeptidase, IPR002468:Peptidase M24A, methionine aminopeptidase, subfamily 2, IPR011991:Winged helix-turn-helix DNA-binding domain" CG4008 11-Aug-17 DroID_v2017_08 "Drer\metap2a, Drer\metap2b" Scer\MAP2 "Cele\T27A8.3, Cele\map-2, Cele\F53B6.5" Xtro\metap2 Mmus\Metap2 Hsap\METAP2 "partially lethal - majority die,recessive,visible,planar polarity defective,wild-type,viable" "eye,wing,anterior,ommatidium,eye photoreceptor cell,ventral,wing vein L5,trichogen cell" FBgn0000117 arm armadillo http://flybase.org/reports/FBgn0000117 "FBgn0029069, FBgn0040191, FBgn0045040" protein_coding_gene "signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR013284 protein binding ; GO:0005515 | inferred from physical interaction with ssp protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P22265 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P46150 inferred from physical interaction with UniProtKB:Q24564 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P91943 protein binding ; GO:0005515 | inferred from physical interaction with Axn protein phosphatase binding ; GO:0019903 | inferred from biological aspect of ancestor with PANTHER:PTN001153077 kinase binding ; GO:0019900 | inferred from physical interaction with Hipk transcription coactivator activity ; GO:0003713 | inferred from direct assay RNA polymerase II transcription coactivator activity ; GO:0001105 | contributes_to inferred from physical interaction with lgs inferred from physical interaction with pygo protein complex binding ; GO:0032403 | inferred from physical interaction with Exo70, Sec10 transcription factor binding ; GO:0008134 | inferred from direct assay alpha-catenin binding ; GO:0045294 | inferred from biological aspect of ancestor with PANTHER:PTN001153077 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Apc2 inferred from physical interaction with Mer protein binding ; GO:0005515 | inferred from physical interaction with Apc2" "wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype ventral furrow formation ; GO:0007370 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype delamination ; GO:0060232 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity dorsal closure ; GO:0007391 | inferred from genetic interaction with ena protein localization to adherens junction ; GO:0071896 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype negative regulation of heart induction by canonical Wnt signaling pathway ; GO:0003136 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype heart formation ; GO:0060914 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype epithelial cell type specification, open tracheal system ; GO:0035153 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype branching morphogenesis of an epithelial tube ; GO:0048754 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement cell fate determination ; GO:0001709 | inferred from mutant phenotype photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype" apical plasma membrane ; GO:0016324 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay catenin complex ; GO:0016342 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay catenin complex ; GO:0016342 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay adherens junction ; GO:0005912 | non-traceable author statement endocytic vesicle ; GO:0030139 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | traceable author statement spot adherens junction ; GO:0005914 | non-traceable author statement zonula adherens ; GO:0005915 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | "Arm, arm, beta-cat, CG11579, t12687 ALR Dm, ARM, EG:86E4.6, l(1)G0410, l(1)G0192, l(1)G0234, l(1)arm, l(1)2Bv, beta-cat-arm, beta-Cat, betacat, Dm Arm, beta-catenin/Arm, bgr;-Cat, beta-catenin" "IPR000225:Armadillo, IPR011989:Armadillo-like helical, IPR013284:Beta-catenin, IPR016024:Armadillo-type fold" CG11579 11-Aug-17 DroID_v2017_08 "Drer\ctnnd2a, Drer\ctnnd2b, Drer\armc3, Drer\ctnnb2, Drer\uckl1a, Drer\armc7, Drer\uckl1b, Drer\ctnnb1, Drer\arvcfb, Drer\si:ch211-243j20.2, Drer\jupb, Drer\pkp4, Drer\armc4, Drer\uprt, Drer\jupa" "Scer\FUR1, Scer\VAC8, Scer\URK1" "Cele\wrm-1, Cele\jac-1, Cele\bar-1, Cele\hmp-2" "Xtro\uprt, Xtro\jup, Xtro\armc3, Xtro\armc4, Xtro\ctnnb1" "Mmus\Ctnnd2, Mmus\Uckl1, Mmus\Armc3, Mmus\Armc4, Mmus\Armc7, Mmus\Ctnnb1, Mmus\Uprt, Mmus\Jup, Mmus\Arvcf, Mmus\Pkp4" "Hsap\ARMC3, Hsap\ARVCF, Hsap\ARMC7, Hsap\RAC1, Hsap\UPRT, Hsap\PKP4, Hsap\CTNND2, Hsap\JUP, Hsap\UCKL1, Hsap\CTNNB1" " larval stage , embryonic stage , oogenesis stage && adult stage | female , embryonic stage | stage >12 , embryonic stage | stage 13-14 , embryonic stage | stage 9 , embryonic stage | stage 13-16 , embryonic stage | late , embryonic stage | stage 13 , larval stage | third instar , embryonic stage | stage 17 , embryonic stage | embryonic cycle 14 , embryonic stage | late && larval stage , adult stage " " embryonic/larval salivary gland

, embryonic central nervous system

, follicle cell

, tracheal system

, peripheral nervous system

, gonad | restricted

, eye-antennal disc

, ventral midline

, proctodeum

, sense organ

, midline glial cell

, embryonic/larval foregut

, imaginal disc

, optic lobe

, labral segment

, larval anus

, ventral nerve cord

, gonad | restricted & anterior

, motor neuron &&of intersegmental nerve

, stomodeum

, mesoderm

, embryonic/larval hindgut

, antennal segment

, supraesophageal ganglion

, Malpighian tubule

, tracheal pit

, oocyte

, longitudinal connective

, neuron

, proventriculus

, embryonic/larval digestive system

, ventral nerve cord commissure

, larval brain

, embryonic/larval posterior spiracle

, embryonic peripheral nervous system

, motor neuron &&of segmental nerve

, larval muscle system

, nurse cell

, posterior embryonic/larval midgut

, head

" "viable,fertile,visible,partially lethal - majority die,lethal,lethal - all die before end of embryonic stage,segment polarity phenotype,heat sensitive,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,recessive,male,female,germline clone,planar polarity defective,cell non-autonomous,somatic clone,cell autonomous,cell polarity defective,cell migration defective,cell shape defective,wild-type,increased cell death,size defective,mitotic cell cycle defective,neuroanatomy defective,memory defective,RU486 conditional,hyperplasia" "wing margin,wing,alula,abdominal sternite 2,abdominal sternite 3,abdominal sternite 4,abdominal sternite 5,abdominal sternite 6,dorsal row,ventral row,tarsal segment,interommatidial bristle,ectopic,somatic clone,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,embryonic head,dorsal closure embryo,embryo,segment,tracheal branch primordium,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,RP2 motor neuron,presumptive embryonic/larval central nervous system,longitudinal connective,commissure,embryonic epidermis,embryonic/first instar larval cuticle,follicle stem cell,embryonic/larval tracheal system,abdominal ventral denticle belt,denticle,dorsal,follicle cell,imaginal disc,gonad,oocyte,ovariole,germline clone,egg,nurse cell & nucleus | germ-line clone,egg chamber,nurse cell,nurse cell ring canal,ventral,ovary,embryonic gnathal segment,embryonic segment,cell autonomous,cardial valve,precursor,embryonic dorsal epidermis,embryonic ventral epidermis,embryonic optic lobe primordium,midgut constriction 2,tracheal metamere,embryonic/larval ganglionic branch,embryonic/larval dorsal branch,embryonic/larval dorsal vessel,denticle belt,stomodeal invagination,pleurum,adult cuticle & abdomen | somatic clone,ommatidium,eye,embryonic Malpighian tubule,maternal effect,contractile ring | somatic clone,midbody | somatic clone,female germline stem cell,germline cell,epithelial cell,cytoskeleton | somatic clone,embryonic/larval dorsal branch 10,spiracular branch 10,MP1 neuron,pCC neuron,dMP2 neuron,vMP2 neuron,embryonic ventral nervous system,nurse cell & nucleus,cytoskeleton,actin filament,nurse cell & actin filament,oocyte & actin filament,border follicle cell,dorsal trunk primordium,posterior spiracle primordium,embryonic leading edge cell,syncytial blastoderm embryo,nucleus | embryonic stage 4 | germline clone,spot adherens junction,actin cytoskeleton | embryonic stage | maternal effect,zonula adherens,embryonic/larval cuticle,adherens junction,ventral furrow,embryonic neuroblast,eye photoreceptor cell,spindle | cleavage stage | maternal effect,cell non-autonomous,pigment cell,dorsal margin photoreceptor,retina,heart primordium,adherens junction | germline clone,salivary gland,dorsal mesothoracic disc & peripodial epithelium | somatic clone | cell autonomous‘±Tub84B.PL,wing hinge primordium,embryonic/first instar larval cuticle & denticleda.G32,wing margin bristle,wing vein,wing sensillum,crossvein,wing disc,lymph gland derived hemocyte | third instar larval stage,macrochaeta,embryonic/first instar larval cuticle & denticle | ectopicda.G32,morphogenetic furrow,antennal disc,T1 beard,wing hinge,anterior compartment,sensory mother cell & dorsal mesothoracic disc | ectopicsd-SG29.1,embryonic/first instar larval cuticle & denticle beltda.G32,embryonic/larval visceral branch,tracheal fusion cell,supernumerary,terminal tracheal cell,direct flight muscle,denticle row 1,interfollicle cell,heat sensitive,midgut constriction 1,abdominal ventral acute muscle 1 founder cell,abdominal ventral acute muscle 2 founder cell,abdominal ventral acute muscle 3 founder cell,dorsal hair,dorsal denticle,dorsal thick hair,dorsal fine hair,pleural membrane,abdominal sternite bristle,sternite,wing hair,testis,dorsal cluster neuron | adult stage,medulla | adult stage,eye disc,posterior,extended germ band embryo,mesothoracic tergum,adult heart,male genitalia,epithelium,female germline cyst,photoreceptor cell,genital disc,nucleus,embryonic/larval salivary gland,wing & macrochaetaC-765,wing & macrochaeta | ectopicC-765" FBgn0015925 csul capsuleen http://flybase.org/reports/FBgn0015925 FBgn0028723 protein_coding_gene protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243 | inferred from mutant phenotype histone-arginine N-methyltransferase activity ; GO:0008469 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 protein-arginine N-methyltransferase activity ; GO:0016274 | inferred from mutant phenotype protein methyltransferase activity ; GO:0008276 | inferred from mutant phenotype "peptidyl-arginine methylation ; GO:0018216 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | inferred from mutant phenotype growth ; GO:0040007 | inferred from mutant phenotype peptidyl-arginine methylation, to symmetrical-dimethyl arginine ; GO:0019918 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype P granule organization ; GO:0030719 | inferred from mutant phenotype pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 nucleus ; GO:0005634 | inferred from direct assay "csul, DART5, JBP1, CG3730, dart5, dPRMT5, PRMT5, dprmt5, Dart5, Csul" "IPR007857:Protein arginine N-methyltransferase PRMT5, IPR025799:Protein arginine N-methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG3730 11-Aug-17 DroID_v2017_08 "Drer\prmt5, Drer\carm1" Scer\HSL7 Cele\prmt-5 Xtro\prmt5 Mmus\Prmt5 Hsap\PRMT5 "viable,male sterile,grandchildless,fertile,female sterile,recessive" "pole cell,testis,spermatozoon,spermatid,spermatid cyst,embryonic abdominal segment,maternal effect" FBgn0263766 CR43683 - http://flybase.org/reports/FBgn0263766 non_protein_coding_gene - - - CR43683 - CR43683 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040828 CG13306 - http://flybase.org/reports/FBgn0040828 protein_coding_gene - - - CG13306 - CG13306 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038300 Mau2 Mau2 sister chromatid cohesion factor http://flybase.org/reports/FBgn0038300 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Nipped-B double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN000483609 axon guidance ; GO:0007411 | inferred from sequence or structural similarity with UniProtKB:O17581 maintenance of mitotic sister chromatid cohesion ; GO:0034088 | inferred from sequence or structural similarity with HGNC:29140 maintenance of mitotic sister chromatid cohesion ; GO:0034088 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 maintenance of mitotic sister chromatid cohesion ; GO:0034088 | inferred from biological aspect of ancestor with PANTHER:PTN000483609 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 SMC loading complex ; GO:0032116 | inferred from biological aspect of ancestor with PANTHER:PTN000483609 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 chromatin ; GO:0000785 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 SMC loading complex ; GO:0032116 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 chromatin ; GO:0000785 | inferred from biological aspect of ancestor with PANTHER:PTN000483609 "Mau-2, FBgn0038300, MAU-2, Mau2, MAU2, CG4203, mau-2" "IPR019440:Chromatid cohesion factor MAU2, IPR011990:Tetratricopeptide-like helical domain" CG4203 11-Aug-17 DroID_v2017_08 Drer\mau2 - Cele\mau-2 Xtro\mau2 Mmus\Mau2 Hsap\MAU2 FBgn0069183 mcl(2)Z0218 mcl(2)Z0218 http://flybase.org/reports/FBgn0069183 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z0218 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0016820 l(1)L7 lethal (1) L7 http://flybase.org/reports/FBgn0016820 - gene - - - "l(1)L7, L7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266635 CR45142 - http://flybase.org/reports/FBgn0266635 non_protein_coding_gene - - - CR45142 - CR45142 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011190 l(1)296-15 lethal (1) 296-15 http://flybase.org/reports/FBgn0011190 FBgn0010201 gene - - - "296-15, l(1)296-15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065925 l(2)SH0147 lethal (2) SH0147 http://flybase.org/reports/FBgn0065925 gene - - - "l(2)SH0147, l(2)SH2 0147" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036305 CG10984 - http://flybase.org/reports/FBgn0036305 protein_coding_gene actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN001192625 actin filament bundle assembly ; GO:0051017 | inferred from biological aspect of ancestor with PANTHER:PTN001192625 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001192625 nucleoplasm ; GO:0005654 | inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001192625 CG10984 - CG10984 11-Aug-17 DroID_v2017_08 "Drer\espnlb, Drer\espn, Drer\espnla, Drer\ankrd11, Drer\ankrd12" Scer\HOS4 "Cele\K02B12.5, Cele\ipla-2, Cele\ipla-3" Xtro\ankrd12 "Mmus\Espnl, Mmus\Ankrd11, Mmus\Ankrd12, Mmus\Espn" "Hsap\ESPNL, Hsap\ESPN, Hsap\ANKRD11, Hsap\ANKRD12" "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC09817 I -0.837062389 1.53646434 -0.521230289 0.725690648 0.257855167 0.649275555 FBgn0028579 phtf phtf http://flybase.org/reports/FBgn0028579 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence model protein dimerization activity ; GO:0046983 | inferred from sequence model" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence model nucleus ; GO:0005634 | inferred from sequence model "phtf, CG3268, d-phtf, BcDNA.GH08636, BcDNA:GH08636" "IPR021980:Transcription factor homeodomain, male germ-cell" CG3268 11-Aug-17 DroID_v2017_08 "Drer\zgc:175264, Drer\phtf2" - "Cele\sri-73, Cele\sri-48, Cele\sri-45, Cele\sri-30, Cele\sri-29, Cele\sri-24, Cele\sri-54, Cele\sri-43, Cele\sri-67, Cele\sri-46, Cele\sri-66, Cele\T10D4.14, Cele\sri-42, Cele\sri-31, Cele\sri-53, Cele\sri-70, Cele\sri-77, Cele\sri-60, Cele\sri-74, Cele\sri-65, Cele\sri-51, Cele\sri-50, Cele\sri-33, Cele\sri-28, Cele\sri-69" Xtro\phtf2 "Mmus\Phtf1, Mmus\Phtf2" "Hsap\PHTF1, Hsap\PHTF2" adult stage male germline stem cell

viable FBgn0003950 unc uncoordinated http://flybase.org/reports/FBgn0003950 FBgn0031160 protein_coding_gene - non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype ciliary basal body ; GO:0036064 | inferred from direct assay ciliary transition zone ; GO:0035869 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay "lLV7, W5, 5, 4, 3, CG1501, l(1)6-3-212, l(1)19Ef, unc, UNC, Unc" IPR006594:LIS1 homology motif CG1501 11-Aug-17 DroID_v2017_08 - - "Cele\F54A3.2, Cele\T08D2.8" - - - "viable,fertile,touch sensitivity defective,recessive,behavior defective,somatic clone,lethal,auditory perception defective,uncoordinated,neurophysiology defective,locomotor behavior defective,touch perception defective" "elongation stage spermatid,spermatid axoneme,elongation stage spermatid & nucleus,olfactory neuron & cilium,scolopidial cilium,spermatocyte & centriole,wing,leg,macrochaeta,adult antennal nerve" FBgn0058457 5.8SrRNA:CR40457 5.8SrRNA:CR40457 http://flybase.org/reports/FBgn0058457 rRNA_gene - - - "CR40457, 5.8SrRNA:CR40457" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265822 CR44611 - http://flybase.org/reports/FBgn0265822 non_protein_coding_gene - - - CR44611 - CR44611 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083264 E(smoDN)529 Enhancer of smoDN 529 http://flybase.org/reports/FBgn0083264 gene - - - E(smoDN)529 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043380 EP787 EP787 http://flybase.org/reports/FBgn0043380 gene - - - "EP(2)0787, EP0787, EP787" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "scutellar bristle,tormogen cell" FBgn0036211 CG5946 - http://flybase.org/reports/FBgn0036211 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000452136 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR001834, InterPro:IPR017927, InterPro:IPR017938 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype" endomembrane system ; GO:0012505 | inferred from direct assay CG5946 "IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR001709:Flavoprotein pyridine nucleotide cytochrome reductase, IPR001834:NADH:cytochrome b5 reductase (CBR), IPR008333:Oxidoreductase, FAD-binding domain, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel" CG5946 11-Aug-17 DroID_v2017_08 "Drer\cyb5r2, Drer\cyb5r1, Drer\cyb5r4, Drer\oxnad1, Drer\cyb5r3" "Scer\AIM33, Scer\PGA3, Scer\MCR1, Scer\CYC2, Scer\CBR1" "Cele\T05H4.4, Cele\hpo-19" "Xtro\cyb5r4, Xtro\cyb5r2, Xtro\cyb5r3, Xtro\oxnad1, Xtro\cyb5r1" "Mmus\Cyb5r2, Mmus\Cyb5rl, Mmus\Cyb5r3, Mmus\Oxnad1, Mmus\Cyb5r4, Mmus\Cyb5r1" "Hsap\CYB5R3, Hsap\CYB5R1, Hsap\CYB5R2, Hsap\CYB5R4, Hsap\CYB5RL, Hsap\OXNAD1" "behavior defective,recessive,viable,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0032172 CG5850 - http://flybase.org/reports/FBgn0032172 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 CG5850 IPR005178:Organic solute transporter subunit alpha/Transmembrane protein 184 CG5850 11-Aug-17 DroID_v2017_08 "Drer\tmem184a, Drer\si:dkey-217f16.5, Drer\tmem184ba, Drer\tmem184c, Drer\tmem184bb" Scer\YKR051W Cele\F40E10.6 "Xtro\tmem184c, Xtro\tmem184b, Xtro\tmem184a" "Mmus\Tmem184a, Mmus\Tmem184c, Mmus\Tmem184b" "Hsap\TMEM184C, Hsap\TMEM184A, Hsap\TMEM184B" "viable,fertile" FBgn0032729 L2HGDH L-2-hydroxyglutarate dehydrogenase http://flybase.org/reports/FBgn0032729 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR023753" lipid particle ; GO:0005811 | inferred from direct assay "L2HGDH, CG10639, dL2HGDH" "IPR006076:FAD dependent oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG10639 11-Aug-17 DroID_v2017_08 Drer\l2hgdh - Cele\Y45G12B.3 Xtro\l2hgdh Mmus\L2hgdh Hsap\L2HGDH "viable,fertile" FBgn0265443 CR44343 - http://flybase.org/reports/FBgn0265443 non_protein_coding_gene - - - "CR44343, lincRNA.301" - CR44343 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020794 oo oculus obscurus http://flybase.org/reports/FBgn0020794 - gene - - - oo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086655 jing jing http://flybase.org/reports/FBgn0086655 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "axon guidance ; GO:0007411 | inferred from mutant phenotype ventral midline development ; GO:0007418 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype tissue regeneration ; GO:0042246 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype specification of segmental identity, maxillary segment ; GO:0007382 | inferred from expression pattern inferred from genetic interaction with Dfd negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype" ESC/E(Z) complex ; GO:0035098 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with ci inferred from sequence or structural similarity with MGI:MGI:1338038 inferred from direct assay "1.28, jing, CT9093, CG9397, CG9403, l(2)01094, l(2)22F3, Jing, AEBP2" IPR013087:Zinc finger C2H2-type CG9397 11-Aug-17 DroID_v2017_08 Drer\aebp2 - - Xtro\aebp2 Mmus\Aebp2 Hsap\AEBP2 " embryonic stage | stage 10-16 , embryonic stage , embryonic stage | stage 9-15 , embryonic stage | stage 9 " " tracheal primordium

anterior , embryonic abdominal segment 8 | restricted

, proctodeum

, ventral midline

, ventral neurogenic region | segmentally repeated

, epidermis &&of embryonic maxillary segment

, embryonic/larval hindgut

, embryonic prothoracic segment | restricted

, anterior embryonic/larval midgut

, posterior embryonic/larval midgut

, supraesophageal ganglion

" " embryonic stage | stage 9-14 , embryonic stage | stage 10-16 " " ventral midline

, tracheal primordium

" FBgn0085497 CG40577 - http://flybase.org/reports/FBgn0085497 protein_coding_gene - - - CG40577 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260657 CG42540 - http://flybase.org/reports/FBgn0260657 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001972 "CG42540, CG13719, CG7468, CG13718, CG32245" "IPR018080:Band 7/stomatin-like, conserved site, IPR001107:Band 7 domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001972:Stomatin family" CG42540 11-Aug-17 DroID_v2017_08 "Drer\stoml3a, Drer\zgc:112408, Drer\stoml3b, Drer\nphs2, Drer\stoml1, Drer\stom" - "Cele\mec-2, Cele\sto-4, Cele\sto-3, Cele\unc-1, Cele\sto-5, Cele\sto-6, Cele\sto-2, Cele\sto-1" "Xtro\stom, Xtro\stoml1, Xtro\stoml3" "Mmus\Stoml3, Mmus\Stom, Mmus\Nphs2, Mmus\Stoml1" "Hsap\STOML1, Hsap\STOML3, Hsap\STOM, Hsap\NPHS2" DRSC23011 K -0.571316278 2.483099691 FBgn0038584 mTerf5 mitochondrial transcription termination factor 5 http://flybase.org/reports/FBgn0038584 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from electronic annotation with InterPro:IPR003690 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003690 transcription from mitochondrial promoter ; GO:0006390 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay "mTerf5, D-MTERF5, CG7175" "IPR003690:Transcription termination factor, mitochondrial/chloroplastic" CG7175 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0031720 CG14013 - http://flybase.org/reports/FBgn0031720 protein_coding_gene - - - CG14013 IPR027887:Protein of unknown function DUF4464 CG14013 11-Aug-17 DroID_v2017_08 Drer\si:ch211-57h10.1 - - - Mmus\1700007G11Rik Hsap\C4orf22 "viable,body color defective" mesothoracic tergum FBgn0039655 CG14507 - http://flybase.org/reports/FBgn0039655 protein_coding_gene phospholipase A2 activity ; GO:0004623 | inferred from electronic annotation with InterPro:IPR001211 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001211 "phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090 lipid catabolic process ; GO:0016042 | inferred from electronic annotation with InterPro:IPR001211, InterPro:IPR013090" - CG14507 "IPR001211:Phospholipase A2, IPR016090:Phospholipase A2 domain, IPR033112:Phospholipase A2, aspartic acid active site, IPR033113:Phospholipase A2, histidine active site" CG14507 11-Aug-17 DroID_v2017_08 "Drer\zgc:92162, Drer\oc90, Drer\pla2g1b" - "Cele\C03H5.4, Cele\C07E3.9, Cele\Y69A2AL.2" "Xtro\pla2g1b, Xtro\pla2g2e" "Mmus\Pla2g10, Mmus\Pla2g2c, Mmus\Pla2g5, Mmus\Oc90, Mmus\Pla2g2a, Mmus\Pla2g2d, Mmus\Pla2g1b, Mmus\Pla2g2e, Mmus\Pla2g2f" "Hsap\PLA2G5, Hsap\PLA2G1B, Hsap\OC90, Hsap\PLA2G2E, Hsap\PLA2G2D, Hsap\PLA2G2A, Hsap\PLA2G2C, Hsap\PLA2G10, Hsap\PLA2G2F" "viable,fertile" FBgn0033917 SmydA-1 "SET and MYND domain containing, arthropod-specific, member 1" http://flybase.org/reports/FBgn0033917 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 cytoplasm ; GO:0005737 | inferred from direct assay "SmydA-1, CG8503" "IPR002893:Zinc finger, MYND-type" CG8503 11-Aug-17 DroID_v2017_08 "Drer\smyd4, Drer\smyd1a, Drer\smyd2b, Drer\smyd3, Drer\smyd2a, Drer\smyd1b" "Scer\SET6, Scer\SET5" "Cele\set-30, Cele\set-18, Cele\set-10" "Xtro\smyd4, Xtro\smyd1, Xtro\smyd5" "Mmus\Smyd3, Mmus\Zmynd15, Mmus\Smyd1, Mmus\Smyd2, Mmus\Smyd4, Mmus\Smyd5" "Hsap\SMYD4, Hsap\SMYD2, Hsap\ZMYND15, Hsap\SMYD1, Hsap\SMYD5, Hsap\SMYD3" viable FBgn0266320 CR44985 - http://flybase.org/reports/FBgn0266320 non_protein_coding_gene - - - CR44985 - CR44985 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065216 l(2)SH2245 lethal (2) SH2245 http://flybase.org/reports/FBgn0065216 gene - - - "l(2)SH2245, l(2)SH2 2245" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039820 CG15554 - http://flybase.org/reports/FBgn0039820 protein_coding_gene - - - "BcDNA:RE10288, CG15554" - CG15554 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0067635 188y 188y http://flybase.org/reports/FBgn0067635 gene - - - 188y - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0031817 CG9531 - http://flybase.org/reports/FBgn0031817 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002052 protein methyltransferase activity ; GO:0008276 | inferred from electronic annotation with InterPro:IPR004556 S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from biological aspect of ancestor with PANTHER:PTN000430779 protein methylation ; GO:0006479 | inferred from electronic annotation with InterPro:IPR004556 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000430914 CG9531 "IPR002052:DNA methylase, N-6 adenine-specific, conserved site, IPR004556:Modification methylase HemK, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR007848:Methyltransferase small domain" CG9531 11-Aug-17 DroID_v2017_08 Drer\hemk1 "Scer\MTQ2, Scer\MTQ1" Cele\mtq-2 Xtro\hemk1 "Mmus\Hemk1, Mmus\N6amt1" "Hsap\N6AMT1, Hsap\HEMK1" DRSC03253 I -0.532977549 -1.501088159 0.798429161 -0.688992968 -0.755058209 -0.305129477 FBgn0027984 l(3)S133501b lethal (3) S133501b http://flybase.org/reports/FBgn0027984 gene - - - "1335/01, l(3)S133501, l(3)S133501b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0026654 l(2)2D8 lethal (2) 2D8 http://flybase.org/reports/FBgn0026654 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)2D8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0021970 l(2)k10004 lethal (2) k10004 http://flybase.net/reports/FBgn0021970.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0051501 nxf4 nuclear export factor 4 http://flybase.org/reports/FBgn0051501 protein_coding_gene - poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from biological aspect of ancestor with PANTHER:PTN000070434 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000070434 "BcDNA:AT07692, CG14604, CG31501, nxf4" "IPR030217:Nuclear RNA export factor, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG31501 11-Aug-17 DroID_v2017_08 "Drer\nxf1, Drer\zgc:153681" Scer\MEX67 "Cele\nxf-2, Cele\nxf-1" Xtro\nxf1 "Mmus\Nxf2, Mmus\Nxf7, Mmus\Nxf1, Mmus\Nxf3" "Hsap\NXF2B, Hsap\NXF5, Hsap\NXF3, Hsap\NXF2, Hsap\NXF1" viable DRSC12548 K 1.179127539 -0.356736203 0.547612129 -0.433458046 -1.572906876 -0.452319842 FBgn0053395 5SrRNA:CR33395 5SrRNA:CR33395 http://flybase.org/reports/FBgn0053395 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33395, 5SrRNA:CR33395" - CR33395 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0270928 VAChT Vesicular acetylcholine transporter http://flybase.org/reports/FBgn0270928 protein_coding_gene drug transmembrane transporter activity ; GO:0015238 | inferred from electronic annotation with InterPro:IPR004734 acetylcholine transmembrane transporter activity ; GO:0005277 | inferred from biological aspect of ancestor with PANTHER:PTN000607168 acetylcholine binding ; GO:0042166 | inferred from biological aspect of ancestor with PANTHER:PTN000607168 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 drug transport ; GO:0015893 | inferred from electronic annotation with InterPro:IPR004734 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001519445 AP-2 adaptor complex ; GO:0030122 | inferred from biological aspect of ancestor with PANTHER:PTN000607168 AP-1 adaptor complex ; GO:0030121 | inferred from biological aspect of ancestor with PANTHER:PTN000607168 "VAcht, vAChT, VAChT, VaChT, vacht, Vacht, CT41182, VACHT, CG12345, CG32848, VACht, Chn, chn" "IPR004734:Multidrug resistance protein, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG32848 11-Aug-17 DroID_v2017_08 "Drer\slc18a2, Drer\slc18a1, Drer\slc18a3b, Drer\slc18a3a" - "Cele\unc-17, Cele\cat-1" "Xtro\slc18a1, Xtro\slc18a3" "Mmus\Slc18a2, Mmus\Slc18a1, Mmus\Slc18a3" "Hsap\SLC18A2, Hsap\SLC18A1, Hsap\SLC18A3" "chemical resistant,lethal,hypoactive,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,wild-type,flight defective,locomotor behavior defective,viable,visible" "mesothoracic extracoxal depressor muscle 66,tormogen cell" FBgn0003227 rec recombination-defective http://flybase.org/reports/FBgn0003227 "FBgn0038367, FBgn0040563, FBgn0051293" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001208 ATP-dependent DNA helicase activity ; GO:0004003 | traceable author statement ATPase activity ; GO:0016887 | traceable author statement DNA-dependent ATPase activity ; GO:0008094 | traceable author statement DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR001208 reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | traceable author statement nucleus ; GO:0005634 | traceable author statement "CG31293, rec1, rec-1, CG4828, CG14875, rec, MCM8" "IPR001208:MCM domain, IPR012340:Nucleic acid-binding, OB-fold, IPR033762:MCM OB domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031327:Mini-chromosome maintenance protein" CG31293 11-Aug-17 DroID_v2017_08 "Drer\mcm8, Drer\mcm6l, Drer\mcm6, Drer\mcmdc2" "Scer\MCM2, Scer\MCM6" Cele\mcm-2 "Xtro\mcm8, Xtro\mcm6, Xtro\mcm6.2" "Mmus\Mcm8, Mmus\Mcm6, Mmus\Mcmdc2" "Hsap\MCMDC2, Hsap\MCM8, Hsap\MCM6" "sterile,heat sensitive,viable" FBgn0040869 CG15763 - http://flybase.org/reports/FBgn0040869 protein_coding_gene - - - CG15763 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035941 CG13313 - http://flybase.org/reports/FBgn0035941 protein_coding_gene - - - CG13313 IPR000859:CUB domain CG13313 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC09984 E 0.901828643 -0.468383896 -1.581960268 -0.10091293 -0.007886799 1.117119912 FBgn0060521 l(3)S102409 lethal (3) S102409 http://flybase.org/reports/FBgn0060521 gene - - - "1024/09, l(3)S102409" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263900 l(3)B29 - http://flybase.org/reports/FBgn0263900 gene - - - l(3)B29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0086708 stv starvin http://flybase.org/reports/FBgn0086708 protein_coding_gene chaperone binding ; GO:0051087 | inferred from electronic annotation with InterPro:IPR003103 heat shock protein binding ; GO:0031072 | inferred from physical interaction with Hsp67Bc positive regulation of protein lipidation ; GO:1903061 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay "CG32130, GH04349, l(3)00543, CG14108, CG10745, stv, Stv, cg32130" IPR003103:BAG domain CG32130 11-Aug-17 DroID_v2017_08 "Drer\bag5, Drer\bag3, Drer\bag4" - - "Xtro\bag4, Xtro\bag3, Xtro\tet2, Xtro\bag5" "Mmus\Bag5, Mmus\Bag4, Mmus\Bag3" "Hsap\BAG5, Hsap\BAG4, Hsap\BAG3" FBgn0037943 CG14722 - http://flybase.org/reports/FBgn0037943 protein_coding_gene - defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 - CG14722 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG14722 11-Aug-17 DroID_v2017_08 "Drer\ik, Drer\wdr55" Scer\JIP5 "Cele\Y44F5A.1, Cele\smu-2" Xtro\wdr55 "Mmus\Ik, Mmus\Wdr55" "Hsap\IK, Hsap\WDR55" viable FBgn0028662 VhaPPA1-1 Vacuolar H[+] ATPase PPA1 subunit 1 http://flybase.org/reports/FBgn0028662 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from sequence model with InterPro:IPR000245,InterPro:IPR002379" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR002379 vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181" "vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000001068 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000813763" "CG7007, vhaPPA1-1, VhaPPA1-1, VhaPPA1, Vha26, V0c''" "IPR000245:V-ATPase proteolipid subunit, IPR002379:V-ATPase proteolipid subunit C-like domain" CG7007 11-Aug-17 DroID_v2017_08 Drer\atp6v0b "Scer\VMA16, Scer\VMA3" Cele\vha-4 Xtro\atp6v0b Mmus\Atp6v0b Hsap\ATP6V0B "lethal,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0260304 GSd460 - http://flybase.org/reports/FBgn0260304 gene - - - GSd460 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259567 GG01019 - http://flybase.org/reports/FBgn0259567 gene - - - GG01019 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein L3 FBgn0262714 Sap130 Sin3A-associated protein 130 http://flybase.org/reports/FBgn0262714 protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001004204 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001004204 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR024137 histone H3 acetylation ; GO:0043966 | inferred from biological aspect of ancestor with PANTHER:PTN001004204 regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN001004204" nucleoplasm ; GO:0005654 | inferred from direct assay STAGA complex ; GO:0030914 | inferred from biological aspect of ancestor with PANTHER:PTN001004204 Sin3-type complex ; GO:0070822 | inferred from direct assay "BcDNA:LD21213, Sap130, CG11006, SAP130, l(3)06924" "IPR024137:Histone deacetylase complex subunit SAP130, IPR031963:Histone deacetylase complex subunit SAP130, C-terminal domain" CG11006 11-Aug-17 DroID_v2017_08 "Drer\sap130b, Drer\sap130a" - - Xtro\sap130 Mmus\Sap130 Hsap\SAP130 FBgn0038243 CG8066 - http://flybase.org/reports/FBgn0038243 protein_coding_gene cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from electronic annotation with InterPro:IPR000010 - - CG8066 IPR000010:Cystatin domain CG8066 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC24633 K 0.657644418 -0.293798388 -0.122258226 -0.046606411 0.444985774 2.018870972 FBgn0011982 tRNA:Ser-AGA-2-1 transfer RNA:Serine-AGA 2-1 http://flybase.org/reports/FBgn0011982 "FBgn0003830, FBgn0011968, FBgn0011979, FBgn0052607, FBgn0060068" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "444-3, tRNA ser7, 777-1, Ser-tRNA-7, tRNA[Ser][[7]], tRNA[[7]][Ser], tRNA[Ser], AE002593.trna14-SerAGA, tRNA:S:AGA:AE002593-d, CR32607, tRNA:ser, tRNA:S, tRNA:S7, tRNA:ser7, tRNA:ser7:12Ed, tRNA[[Ser]], chrX.trna23-SerAGA, tRNA-Ser-AGA-2-1, tRNA:Ser-AGA-2-1, tRNA:S7:12Ed, UCU" - CR32607 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001229 Hsp67Bc Heat shock gene 67Bc http://flybase.org/reports/FBgn0001229 - protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with stv chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model positive regulation of protein lipidation ; GO:1903061 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from direct assay regulation of translational initiation by eIF2 alpha phosphorylation ; GO:0010998 | inferred from mutant phenotype Z disc ; GO:0030018 | colocalizes_with inferred from direct assay "Dmel18.0, Hsp67Bc, hsp67B, CG4190, Hspg3, gene3, gene 3, gene5, gene-3, Hsp-G3, small hsp locus 67B, HSP67Bc, Dm-HSP67Bc, HSPB8, HSP67, Hsp67BC, HSP67BC" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4190 11-Aug-17 DroID_v2017_08 "Drer\hspb12, Drer\hspb6, Drer\hspb1, Drer\hspb7, Drer\hspb15, Drer\hspb11, Drer\hspb8, Drer\si:dkey-1k23.3, Drer\hspb2, Drer\hspb9, Drer\cryaba, Drer\hspb3, Drer\cryaa" - "Cele\sip-1, Cele\ZK1128.7, Cele\hsp-12.2, Cele\hsp-16.11, Cele\hsp-43, Cele\F08H9.3, Cele\hsp-16.2, Cele\hsp-16.49, Cele\Y55F3BR.6, Cele\hsp-16.1, Cele\hsp-17, Cele\hsp-12.3, Cele\hsp-12.6, Cele\F08H9.4, Cele\hsp-16.48, Cele\hsp-12.1, Cele\hsp-16.41" "Xtro\hsp30d, Xtro\hspb3, Xtro\hsp30e, Xtro\hspb1, Xtro\cryab, Xtro\cryaa, Xtro\uqcrh, Xtro\hspb8, Xtro\hspb6, Xtro\hspb2" "Mmus\Hspb1, Mmus\Hspb2, Mmus\Cryab, Mmus\Hspb6, Mmus\Hspb7, Mmus\Hspb9, Mmus\Hspb8, Mmus\Cryaa, Mmus\Hspb3" "Hsap\LOC102724652, Hsap\CRYAA, Hsap\HSPB6, Hsap\HSPB1, Hsap\CRYAB, Hsap\HSPB7, Hsap\HSPB8, Hsap\HSPB9, Hsap\HSPB2, Hsap\HSPB3" " larval stage--pupal stage , prepupal stage , embryonic stage | >= 7hr " "viable,fertile" FBgn0015818 Spx Spliceosomal protein on the X http://flybase.org/reports/FBgn0015818 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000005846 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" precatalytic spliceosome ; GO:0071011 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000005846 "CG3780, SPX, Spx, spx, SF3B4" "IPR000504:RNA recognition motif domain, IPR034159:SF3B4, RNA recognition motif 2, IPR034158:SF3B4, RNA recognition motif 1" CG3780 11-Aug-17 DroID_v2017_08 Drer\sf3b4 Scer\HSH49 "Cele\arp-6, Cele\sap-49" Xtro\sf3b4 Mmus\Sf3b4 Hsap\SF3B4 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC18720 K -0.67781696 0.175211295 -0.166514163 -0.076534338 -1.865229689 -1.261625145 FBgn0277431 l(3)psg17 - http://flybase.org/reports/FBgn0277431 gene - - - "l(3)psg17, psg17" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260104 2L3191 - http://flybase.org/reports/FBgn0260104 gene - - - 2L3191 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval dorsal trunk,somatic clone" FBgn0036063 CG6674 - http://flybase.org/reports/FBgn0036063 protein_coding_gene - - - CG6674 IPR029338:Tumour suppressing sub-chromosomal transferable candidate 4 CG6674 11-Aug-17 DroID_v2017_08 Drer\tssc4 - - Xtro\tssc4 Mmus\Tssc4 Hsap\TSSC4 viable FBgn0051946 tRNA:Arg-TCT-3-1 transfer RNA:Arginine-TCT 3-1 http://flybase.org/reports/FBgn0051946 tRNA_gene AGA codon-amino acid adaptor activity ; GO:0033447 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033447 cytosol ; GO:0005829 | inferred by curator from GO:0033447 "AE002638.trna12-ArgTCT, tRNA:R:TCT:AE002638-b, CR31946, chr2L.trna5-ArgTCT, tRNA-Arg-TCT-3-1, tRNA:Arg-TCT-3-1, tRNA:CR31946, AGA" - CR31946 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010645 l(2)08014 lethal (2) 08014 http://flybase.org/reports/FBgn0010645 - gene - - - l(2)08014 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259728 CG42382 - http://flybase.org/reports/FBgn0259728 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 - - "CG42382, CG8016" "IPR000571:Zinc finger, CCCH-type" CG42382 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113e8.11, Drer\rad51d" - Cele\ccch-3 Xtro\rad51d Mmus\Rad51d - "viable,visible" mesothoracic tergum FBgn0035649 CG10483 - http://flybase.org/reports/FBgn0035649 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004342 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000081883 CG10483 "IPR004331:SPX domain, IPR004342:EXS, C-terminal" CG10483 11-Aug-17 DroID_v2017_08 "Drer\xpr1b, Drer\xpr1a" "Scer\SYG1, Scer\VTC3, Scer\VTC2, Scer\ERD1, Scer\VTC4" Cele\Y39A1A.22 Xtro\xpr1 Mmus\Xpr1 Hsap\XPR1 "viable,fertile" FBgn0034054 CG8366 - http://flybase.org/reports/FBgn0034054 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR011604 nuclease activity ; GO:0004518 | inferred from electronic annotation with InterPro:IPR011604 - - CG8366 "IPR011335:Restriction endonuclease type II-like, IPR011604:Exonuclease, phage-type/RecB, C-terminal, IPR019080:YqaJ viral recombinase" CG8366 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC07153 I 0.538364737 1.529012203 0.973629552 1.034407923 0.326281002 0.314302639 FBgn0031883 Caper Caper http://flybase.org/reports/FBgn0031883 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR006509 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D inferred from genetic interaction with rl positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleoplasm ; GO:0005654 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CC1.3, CAPER, HCC1, cg11266, CG11266, Caper, igru" "IPR000504:RNA recognition motif domain, IPR006509:Splicing factor, RBM39-like, IPR029123:Splicing factor RBM39, linker" CG11266 11-Aug-17 DroID_v2017_08 "Drer\rbm39b, Drer\lemd3, Drer\rbm39a" Scer\NOP13 Cele\Y55F3AM.3 "Xtro\rbm23, Xtro\rbm39, Xtro\lemd3" "Mmus\Lemd3, Mmus\Lemd2, Mmus\Rbm39" "Hsap\LEMD2, Hsap\RBM39, Hsap\RBM23, Hsap\LEMD3" "viable,visible" trichogen cell DRSC02137 EK 0.549039671 0.567433218 -0.139840001 1.841334739 -2.366422357 -1.697928933 FBgn0086071 snoRNA:Or-CD11b - http://flybase.org/reports/FBgn0086071 snoRNA_gene - - - "snoRNA:Or-CD11b, Or-cd11b, CR34700" - CR34700 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037448 CG15186 - http://flybase.org/reports/FBgn0037448 protein_coding_gene - - - CG15186 - CG15186 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065738 l(2)SH0531 lethal (2) SH0531 http://flybase.org/reports/FBgn0065738 gene - - - "l(2)SH0531, l(2)SH2 0531" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014987 l(2)46Dc lethal (2) 46Dc http://flybase.org/reports/FBgn0014987 - gene - - - "IX, l(2)46Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051067 CG31067 - http://flybase.org/reports/FBgn0051067 protein_coding_gene - - - CG31067 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264278 Su(Mir)1E2-4 - http://flybase.org/reports/FBgn0264278 gene - - - Su(Mir)1E2-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085310 CG34281 - http://flybase.org/reports/FBgn0085310 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34281, CG14328" - CG34281 11-Aug-17 DroID_v2017_08 - - - - Mmus\Krtap19-4 "Hsap\KRTAP19-1, Hsap\KRTAP19-3" viable FBgn0005521 l(2)37Fh lethal (2) 37Fh http://flybase.org/reports/FBgn0005521 - gene - - - "l(2)C188, l(2)37Fh" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0064180 htz hitzschlag http://flybase.org/reports/FBgn0064180 gene - - - htz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003241 rf roof wings http://flybase.org/reports/FBgn0003241 - gene - - - rf - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0034490 CG9864 - http://flybase.org/reports/FBgn0034490 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 "CT27832, CG9864" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG9864 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-513e17.1, Drer\slc17a8, Drer\ppt1, Drer\slc17a9a, Drer\slc17a6b, Drer\slc17a6a, Drer\slc17a5, Drer\slc17a7a" "Scer\YIL166C, Scer\DAL5, Scer\GAL2, Scer\TNA1, Scer\THI73" "Cele\R10D12.1, Cele\slc-17.4, Cele\C35A5.3, Cele\T27D12.1, Cele\T22F3.7, Cele\slc-17.3, Cele\slc-17.2, Cele\T22F3.11, Cele\K08C7.1, Cele\T19D12.9, Cele\T22F3.10, Cele\F10C2.7, Cele\C01B4.7, Cele\Y19D10A.8, Cele\slc-17.9, Cele\W04C9.6, Cele\Y19D10A.4, Cele\cima-1, Cele\F56A4.12, Cele\C39E9.7, Cele\Y51B9A.6, Cele\C18H9.5, Cele\T22F3.8, Cele\T01H3.3, Cele\slc-17.8, Cele\C18D1.2, Cele\slc-17.1, Cele\F56A4.10, Cele\H11E01.2, Cele\Y4C6B.4, Cele\K11G9.5, Cele\F11A5.9, Cele\F59A1.13, Cele\F47B8.10, Cele\F41C3.2, Cele\T28H11.8, Cele\M117.1, Cele\D1046.4, Cele\T19D12.10, Cele\Y15E3A.4, Cele\slc-17.6, Cele\slc-17.5, Cele\M162.5, Cele\Y4C6B.3, Cele\T02B11.6, Cele\slc-17.7, Cele\Y19D10A.5, Cele\F44E7.7, Cele\C01B4.8, Cele\Y19D10A.11" "Xtro\slc17a7, Xtro\slc22a5" "Mmus\Slc17a2, Mmus\Slc17a1, Mmus\Slc17a7, Mmus\Slc17a6, Mmus\Slc37a4, Mmus\Slc17a4, Mmus\Slc17a3, Mmus\Slc17a5, Mmus\Slc17a8, Mmus\Slc22a2" "Hsap\SLC17A1, Hsap\SLC17A8, Hsap\SLC17A2, Hsap\SLC37A4, Hsap\SLC17A4, Hsap\SLC17A3, Hsap\SLC17A6, Hsap\SLC17A7, Hsap\SLC17A5" viable FBgn0005199 l(3)ac lethal (3) accessory http://flybase.org/reports/FBgn0005199 - gene - - - l(3)ac - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024530 l(3)L0499 lethal (3) L0499 http://flybase.org/reports/FBgn0024530 - gene - - - l(3)L0499 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260382 GSd462 - http://flybase.org/reports/FBgn0260382 gene - - - GSd462 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0038977 CG5376 - http://flybase.org/reports/FBgn0038977 protein_coding_gene - - - CG5376 - CG5376 11-Aug-17 DroID_v2017_08 - - - - - - viable "germline cell,male" FBgn0265347 CR44301 - http://flybase.org/reports/FBgn0265347 non_protein_coding_gene - - - CR44301 - CR44301 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062685 EP1509 EP1509 http://flybase.org/reports/FBgn0062685 gene - - - "EP(X)1509, EP1509" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082940 snoRNA:Me28S-C3227a snoRNA:Me28S-C3227a http://flybase.org/reports/FBgn0082940 snoRNA_gene - - - "snoRNA:Me28S-C3227a, Me28S-Cm3227a, Me28S-C3227a, CR34533" - CR34533 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053802 His-Psi:CR33802 His-Psi:CR33802 http://flybase.org/reports/FBgn0053802 pseudogene_attribute - - - "CR33802, His-Psi:CR33802" - CR33802 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036272 CG4300 - http://flybase.org/reports/FBgn0036272 protein_coding_gene spermine synthase activity ; GO:0016768 | inferred from biological aspect of ancestor with PANTHER:PTN000900684 spermine biosynthetic process ; GO:0006597 | inferred from biological aspect of ancestor with PANTHER:PTN000900684 cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.387, CG4300" "IPR001045:Spermidine/spermine synthases, IPR030374:Polyamine biosynthesis domain, IPR015576:Spermine synthase, animal, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG4300 11-Aug-17 DroID_v2017_08 Drer\sms "Scer\SPE3, Scer\SPE4" Cele\spds-1 "Xtro\sms, Xtro\srm" "Mmus\Gm14680, Mmus\Srm, Mmus\Sms" "Hsap\SMS, Hsap\SRM" "viable,fertile" FBgn0030938 CG15047 - http://flybase.org/reports/FBgn0030938 protein_coding_gene - - - CG15047 "IPR015940:Ubiquitin-associated domain, IPR009060:UBA-like" CG15047 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable" FBgn0026659 l(2)17E1 lethal (2) 17E1 http://flybase.org/reports/FBgn0026659 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)17E1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0259590 B0756 - http://flybase.org/reports/FBgn0259590 gene - - - B0756 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,submarginal cell,wing vein" FBgn0027186 l(2)60A-F lethal (2) 60A-F http://flybase.org/reports/FBgn0027186 - gene - - - l(2)60A-F - - 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,lethal,recessive" FBgn0025343 anon-25Dd anon-25Dd http://flybase.org/reports/FBgn0025343 - gene double-stranded RNA binding ; GO:0003725 | inferred from direct assay - - "#6, anon-25Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031574 CG3964 - http://flybase.org/reports/FBgn0031574 protein_coding_gene - protein polyglutamylation ; GO:0018095 | inferred from electronic annotation with InterPro:IPR027748 neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG3964 "IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027748:Tubulin polyglutamylase TTLL-4" CG3964 11-Aug-17 DroID_v2017_08 "Drer\ttll5, Drer\ttll4" - "Cele\ttll-4, Cele\ttll-5" Xtro\ttll4 "Mmus\Ttll4, Mmus\Ttll5" "Hsap\TTLL4, Hsap\TTLL5" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0011147 l(1)Q223 lethal (1) Q223 http://flybase.org/reports/FBgn0011147 FBgn0010210 gene - - - l(1)Q223 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0277417 l(3)psg8 - http://flybase.org/reports/FBgn0277417 gene - - - "l(3)psg8, psg8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027348 bgm bubblegum http://flybase.org/reports/FBgn0027348 "FBgn0027881, FBgn0028908" protein_coding_gene long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from sequence or structural similarity long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from direct assay long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype long-chain fatty acid metabolic process ; GO:0001676 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype fatty acid metabolic process ; GO:0006631 | inferred from mutant phenotype - "CG4501, bgm, BG:DS01514.2, 2a9hom, BG:DS0514.2, Bgm" IPR000873:AMP-dependent synthetase/ligase CG4501 11-Aug-17 DroID_v2017_08 "Drer\acsl5, Drer\acsl1a, Drer\acsbg1, Drer\acsbg2, Drer\acsl1b, Drer\acsl4a, Drer\acsl4b, Drer\acsl2, Drer\acsl3b, Drer\acsl6" "Scer\FAA2, Scer\FAA3, Scer\FAA1, Scer\FAA4" "Cele\acs-18, Cele\acs-15, Cele\acs-5" "Xtro\acsl5, Xtro\acsbg1, Xtro\acsl1, Xtro\acsbg2, Xtro\acsl6, Xtro\acsl4" "Mmus\Acsl1, Mmus\Acsl4, Mmus\Acsl5, Mmus\Acsl3, Mmus\Acsbg1, Mmus\Acsl6, Mmus\Acsbg2, Mmus\1700061G19Rik" "Hsap\ACSL4, Hsap\ACSL5, Hsap\ACSBG1, Hsap\ACSL6, Hsap\ACSL1, Hsap\ACSL3, Hsap\ACSBG2" "viable,fertile,aging defective,recessive,visual behavior defective,lethal,partially lethal - majority die,visible" "optic lobe,lamina,retina & cell body,photoreceptor cell & axon,mesothoracic tergum" DRSC03495 IEK -2.103706258 -0.789295605 1.458442373 -3.034931862 1.596038381 1.65697295 FBgn0011586 e(r) enhancer of rudimentary http://flybase.org/reports/FBgn0011586 FBgn0030068 protein_coding_gene - cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR000781 pyrimidine nucleotide biosynthetic process ; GO:0006221 | inferred from electronic annotation with InterPro:IPR000781 positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with dx inferred from genetic interaction with N nucleus ; GO:0005634 | inferred from direct assay "CG1871, ER, e(r), ER_DROME" IPR000781:Enhancer of rudimentary CG1871 11-Aug-17 DroID_v2017_08 Drer\erh - "Cele\T21C9.4, Cele\F35G12.11" Xtro\erh Mmus\Erh Hsap\ERH " adult stage | female , adult stage | male " "viable,fertile,wild-type,partially lethal - majority live,visible" trichogen cell FBgn0020058 E(w[a])706 E(w[a])706 http://flybase.org/reports/FBgn0020058 - gene - - - "E706, E(w[a])706" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,eye color defective" pigment cell FBgn0262437 mir-274 mir-274 stem loop http://flybase.org/reports/FBgn0262437 miRNA_gene - - - "dme-mir-274, mir-274, miR-274, CR42996, CR33582, dme-miR-274" - CR42996 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "wing,eye" FBgn0016021 l(3)85Ak lethal (3) 85Ak http://flybase.org/reports/FBgn0016021 - gene - - - l(3)85Ak - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043040 l(2)42Ba lethal (2) 42Ba http://flybase.org/reports/FBgn0043040 gene - - - l(2)42Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084840 l(3)S023901 l(3)S023901 http://flybase.org/reports/FBgn0084840 gene - - - l(3)S023901 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265152 CR44221 - http://flybase.org/reports/FBgn0265152 non_protein_coding_gene - - - CR44221 - CR44221 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035210 msd5 mitotic spindle density 5 http://flybase.org/reports/FBgn0035210 protein_coding_gene - mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype HAUS complex ; GO:0070652 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "msd5, CG2213, Dgt7" - CG2213 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0037102 CRIF CR6-interacting factor http://flybase.org/reports/FBgn0037102 protein_coding_gene - cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR018472 positive regulation of production of siRNA involved in RNA interference ; GO:1903705 | inferred from mutant phenotype cellular response to virus ; GO:0098586 | inferred from mutant phenotype positive regulation of RNA interference ; GO:1900370 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR018472 perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "CG7172, anon-WO0118547.316, CRIF, dCRIF" IPR018472:Growth arrest/ DNA-damage-inducible protein-interacting protein 1 CG7172 11-Aug-17 DroID_v2017_08 Drer\gadd45gip1 - Cele\K07A1.10 Xtro\gadd45gip1 Mmus\Gadd45gip1 Hsap\GADD45GIP1 "viable,visible" trichogen cell FBgn0001933 l(2)25Ef lethal (2) 25Ef http://flybase.org/reports/FBgn0001933 - gene - - - "jf30, l(2)gdh-10, l(2)jf30, l(2)gdh10, l(2)25Ef" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029093 cathD cathD http://flybase.org/reports/FBgn0029093 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern apoptotic process ; GO:0006915 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 lysosome ; GO:0005764 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG1548, CT3996, CATH, T17, cathD, CathD, CTSD" "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR012848:Aspartic peptidase, N-terminal, IPR033144:Cathepsin D, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG1548 11-Aug-17 DroID_v2017_08 "Drer\ren, Drer\ctsd, Drer\zgc:63831, Drer\zgc:103530, Drer\nots" "Scer\YPS5, Scer\BAR1, Scer\YPS7, Scer\YPS3, Scer\MKC7, Scer\YPS1, Scer\YGL258W-A, Scer\YPS6, Scer\PEP4" "Cele\asp-16, Cele\asp-18, Cele\asp-19, Cele\asp-15, Cele\asp-14, Cele\asp-4, Cele\asp-13, Cele\asp-1, Cele\asp-2, Cele\asp-5, Cele\asp-6, Cele\asp-12, Cele\asp-9, Cele\asp-3, Cele\asp-10, Cele\asp-8, Cele\asp-17, Cele\asp-7" "Xtro\napsa, Xtro\pgc, Xtro\LOC100489529, Xtro\bace1, Xtro\ren, Xtro\LOC496913, Xtro\pga4, Xtro\bace2, Xtro\LOC613063, Xtro\LOC101735147, Xtro\ctse, Xtro\ctsd" "Mmus\Ren2, Mmus\Pgc, Mmus\Cym, Mmus\Napsa, Mmus\Bace2, Mmus\Ctsd, Mmus\Ctse, Mmus\Pga5, Mmus\Ren1, Mmus\Bace1" "Hsap\REN, Hsap\CTSE, Hsap\PGC, Hsap\BACE1, Hsap\PGA3, Hsap\PGA5, Hsap\BACE2, Hsap\NAPSA, Hsap\CTSD, Hsap\PGA4" "viable,fertile,increased cell death,conditional,cell death defective,decreased cell death" "adult brain,conditional,egg chamber,nurse cell,eye,spermatogonial cyst,male germline cell" FBgn0027147 l(3)71CDc lethal (3) 71CDc http://flybase.org/reports/FBgn0027147 - gene - - - l(3)71CDc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060349 l(3)S142215b lethal (3) S142215b http://flybase.org/reports/FBgn0060349 gene - - - "1422/15, l(3)S142215b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0038738 CG4572 - http://flybase.org/reports/FBgn0038738 protein_coding_gene serine-type carboxypeptidase activity ; GO:0004185 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 dsRNA transport ; GO:0033227 | inferred from mutant phenotype proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 - "CT14806, anon-WO02059370.13, CG4572" "IPR001563:Peptidase S10, serine carboxypeptidase, IPR018202:Serine carboxypeptidase, serine active site, IPR029058:Alpha/Beta hydrolase fold, IPR033124:Serine carboxypeptidases, histidine active site" CG4572 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-122f10.4, Drer\cpvl" "Scer\PRC1, Scer\YBR139W, Scer\KEX1" "Cele\K10C2.1, Cele\Y32F6A.5, Cele\C08H9.1, Cele\ctsa-2, Cele\F32A5.3, Cele\ctsa-1, Cele\Y16B4A.2, Cele\F41C3.5, Cele\F13D12.6" "Xtro\cpvl, Xtro\ctsa" "Mmus\Ctsa, Mmus\Scpep1, Mmus\Cpvl" "Hsap\SCPEP1, Hsap\CTSA, Hsap\CPVL" "viable,fertile" FBgn0015826 T-C9.12 T-C9.12 http://flybase.org/reports/FBgn0015826 - gene - - - T-C9.12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259957 CG42467 - http://flybase.org/reports/FBgn0259957 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG42467 IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42467 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011482 l(3)neo49 lethal (3) neo49 http://flybase.org/reports/FBgn0011482 - gene - - - l(3)neo49 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082611 aact anti-activin http://flybase.org/reports/FBgn0082611 gene - - - "AACT, aact" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265556 12.95 - http://flybase.org/reports/FBgn0265556 gene - - - 12.95 - - 11-Aug-17 DroID_v2017_08 - - - - - - learning defective FBgn0004018 wo white ocelli http://flybase.org/reports/FBgn0004018 - gene - - - wo - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" ocellus pigment granule FBgn0002327 l(3)86Ff lethal (3) 86Ff http://flybase.org/reports/FBgn0002327 - gene - - - "l(3)S063512, ck6, l(3)ck6, l(3)86Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0259639 B1211 - http://flybase.org/reports/FBgn0259639 gene - - - B1211 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,unguis" FBgn0016732 SR3-2 Suppressor of Ras85D 3-2 http://flybase.org/reports/FBgn0016732 - gene - - - SR3-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067745 l(1)G0265 lethal (1) G0265 http://flybase.org/reports/FBgn0067745 gene - - - l(1)G0265 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0017628 Eig44C Eig44C http://flybase.org/reports/FBgn0017628 - gene - - - "Eig44, Eig44C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003302 rux roughex http://flybase.org/reports/FBgn0003302 - protein_coding_gene - regulation of meiotic nuclear division ; GO:0040020 | traceable author statement eye-antennal disc morphogenesis ; GO:0007455 | non-traceable author statement mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype regulation of exit from mitosis ; GO:0007096 | traceable author statement regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "rux, Rux, CG4336" IPR009259:Drosophila roughex CG4336 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , larval stage , adult stage , larval stage && adult stage " imaginal disc

"viable,locomotor behavior defective,fertile,visible,recessive,male sterile,cytokinesis defective,wild-type,mitotic cell cycle defective" "eye,cyst cell,Nebenkern,onion stage spermatid,mitotic cell cycle,photoreceptor cell,S phase | ectopic,eye disc,photoreceptor cell R8" FBgn0267902 CR46190 - http://flybase.org/reports/FBgn0267902 pseudogene_attribute - - - "CR46190, CG12717-related" - CR46190 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259311 EP-M32 - http://flybase.org/reports/FBgn0259311 gene - - - EP-M32 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0259591 B0771 - http://flybase.org/reports/FBgn0259591 gene - - - B0771 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "macrochaeta,supernumerary" FBgn0065380 l(2)SH1667 lethal (2) SH1667 http://flybase.org/reports/FBgn0065380 gene - - - "l(2)SH1667, l(2)SH2 1667" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031728 Hsp60C Heat shock protein 60C http://flybase.org/reports/FBgn0031728 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002423, InterPro:IPR018370 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" protein refolding ; GO:0042026 | inferred from electronic annotation with InterPro:IPR001844 protein import into mitochondrial intermembrane space ; GO:0045041 | inferred from biological aspect of ancestor with PANTHER:PTN000143508 oogenesis ; GO:0048477 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:P10809 chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 open tracheal system development ; GO:0007424 | inferred from mutant phenotype 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 'de novo' protein folding ; GO:0006458 | inferred from sequence or structural similarity with UniProtKB:P10809 female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype apoptotic mitochondrial changes ; GO:0008637 | inferred from biological aspect of ancestor with PANTHER:PTN000143510 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P10809 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000888029 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000143507 "CG7235, bs36d10.y1, Hsp60C, A4V087_DROME, Hsp64, Dm25E, HSP60C" "IPR018370:Chaperonin Cpn60, conserved site, IPR001844:Chaperonin Cpn60, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG7235 11-Aug-17 DroID_v2017_08 Drer\hspd1 "Scer\TCM62, Scer\HSP60" Cele\hsp-60 Xtro\hspd1 Mmus\Hspd1 Hsap\HSPD1 "sterile,flight defective,partially lethal - majority die,some die during first instar larval stage,viable" "embryonic/larval trachea,eye,antenna,macrochaeta,testis,seminal vesicle" DRSC29438 K 0.475078311 -0.175850628 -0.115676115 -0.299778593 0.635373882 -1.624587631 FBgn0259662 B0572 - http://flybase.org/reports/FBgn0259662 gene - - - B0572 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0001362 l(1)1Fa lethal (1) 1Fa http://flybase.org/reports/FBgn0001362 - gene - - - l(1)1Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051718 Ir31a Ionotropic receptor 31a http://flybase.org/reports/FBgn0051718 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir31a, IR31a, CG31718, DmelIR31a" IPR001320:Ionotropic glutamate receptor CG31718 11-Aug-17 DroID_v2017_08 "Drer\grid1a, Drer\LOC100537813, Drer\grid1b" - Cele\glr-8 - "Mmus\Grik4, Mmus\Grik5, Mmus\Grid1" "Hsap\GRID1, Hsap\GRIK4" "viable,fertile" FBgn0262842 CG43206 - http://flybase.org/reports/FBgn0262842 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR015089 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from biological aspect of ancestor with PANTHER:PTN001035181 - mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001035181 "CG43206, chr3L_16559870_16560394.0" IPR015089:Cytochrome b-c1 complex subunit 10 CG43206 11-Aug-17 DroID_v2017_08 - - Cele\ucr-11 - Mmus\Uqcr11 Hsap\UQCR11 FBgn0035150 Rev1 Rev1 http://flybase.org/reports/FBgn0035150 protein_coding_gene "damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR012112, InterPro:IPR017961 deoxycytidyl transferase activity ; GO:0017125 | non-traceable author statement deoxycytidyl transferase activity ; GO:0017125 | inferred from sequence or structural similarity with SGD:S000005873" error-prone translesion synthesis ; GO:0042276 | inferred from electronic annotation with InterPro:IPR012112 regulation of double-strand break repair via homologous recombination ; GO:0010569 | inferred from mutant phenotype translesion synthesis ; GO:0019985 | non-traceable author statement translesion synthesis ; GO:0019985 | inferred from sequence or structural similarity with SGD:S000005873 replication fork ; GO:0005657 | inferred from sequence or structural similarity with SGD:S000005873 "Rev1, DmREV1, CG12189, AAF47401, drev1, DmRev1, dREV1, REV1, dRev1, rev1" "IPR017961:DNA polymerase, Y-family, little finger domain, IPR001126:UmuC domain, IPR001357:BRCT domain, IPR012112:DNA repair protein, Rev1, IPR031991:DNA repair protein Rev1, C-terminal" CG12189 11-Aug-17 DroID_v2017_08 Drer\rev1 Scer\REV1 Cele\rev-1 Xtro\rev1 Mmus\Rev1 Hsap\REV1 "radiation sensitive,viable" FBgn0020814 l(3)L3999 lethal (3) L3999 http://flybase.org/reports/FBgn0020814 - gene - - - l(3)L3999 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027334 l(1)G0004 lethal (1) G0004 http://flybase.org/reports/FBgn0027334 FBgn0031105 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000981817 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q9NRX1 "CG11738, l(1)G0004, l(G0004)" "IPR004088:K Homology domain, type 1, IPR004087:K Homology domain" CG11738 11-Aug-17 DroID_v2017_08 Drer\pno1 Scer\PNO1 Cele\Y53C12B.2 Xtro\pno1 Mmus\Pno1 Hsap\PNO1 "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0024842 per::Dpse\per per::Dpse\per http://flybase.org/reports/FBgn0024842 - engineered_fusion_gene - - - per::Dpse\per - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004019 wobA wobbly A http://flybase.org/reports/FBgn0004019 - gene - - - wobA - - 11-Aug-17 DroID_v2017_08 - - - - - - uncoordinated FBgn0051471 tRNA:Thr-AGT-1-7 transfer RNA:Threonine-AGT 1-7 http://flybase.org/reports/FBgn0051471 tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "AE002708.trna22-ThrAGT, tRNA:T:AGT:AE002708-b, CR31471, tRNA[[Thr]], chr3R.trna28-ThrAGT, tRNA-Thr-AGT-1-7, tRNA:Thr-AGT-1-7, tRNA:CR31471, ACU" - CR31471 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035687 CG13296 - http://flybase.org/reports/FBgn0035687 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG13296 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG13296 11-Aug-17 DroID_v2017_08 "Drer\zgc:173619, Drer\prdm13, Drer\zbtb12.2" - Cele\fezf-1 - "Mmus\Prdm13, Mmus\Zbtb12" "Hsap\PRDM13, Hsap\ZNF366, Hsap\ZBTB12" "viable,visible" trichogen cell FBgn0265017 CR43751 - http://flybase.org/reports/FBgn0265017 non_protein_coding_gene - - - "CR43751, CG43751, CG15383" - CR43751 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058209 CG40209 - http://flybase.org/reports/FBgn0058209 protein_coding_gene - - - CG40209 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011431 l(3)j11B2 lethal (3) j11B2 http://flybase.org/reports/FBgn0011431 FBgn0024524 gene - - - "l(3)j3E5, l(3)j11B2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038427 ema endosomal maturation defective http://flybase.org/reports/FBgn0038427 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab39 endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from genetic interaction withFB:FBgn0261241 integral component of membrane ; GO:0016021 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay late endosome ; GO:0005770 | colocalizes_with inferred from direct assay "ema, CG12753, Ema" IPR019155:Uncharacterised protein family FPL CG12753 11-Aug-17 DroID_v2017_08 Drer\clec16a - Cele\gop-1 Xtro\clec16a Mmus\Clec16a Hsap\CLEC16A "neuroanatomy defective,recessive,lethal - all die before end of P-stage,some die during P-stage,viable" "terminal bouton,endosome,terminal boutonExel7330),neuromuscular junctionExel7330)" FBgn0003716 tkv thickveins http://flybase.org/reports/FBgn0003716 FBgn0010572 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000333, InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from electronic annotation with InterPro:IPR000333 transforming growth factor beta binding ; GO:0050431 | inferred from physical interaction with dpp protein binding ; GO:0005515 | inferred from physical interaction with Dad transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from genetic interaction with dpp transforming growth factor beta receptor activity, type I ; GO:0005025 | non-traceable author statement transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement" "protein phosphorylation ; GO:0006468 |... electronic annotation with InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR008271 <> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <> imaginal disc-derived wing morphogenesis ; GO:0007476 |... mutant phenotype <> dorsal closure ; GO:0007391 |... mutant phenotype <> spectrosome organization ; GO:0030721 |... mutant phenotype <> imaginal disc-derived wing morphogenesis ; GO:0007476 |... mutant phenotype inferred from genetic interaction with dpp <> compound eye morphogenesis ; GO:0001745 |... mutant phenotype <> open tracheal system development ; GO:0007424 | non-traceable author statement <> transforming growth factor beta receptor signaling pathway ; GO:0007179 |... genetic interaction with dpp inferred from physical interaction with dpp <> anterior/posterior pattern specification, imaginal disc ; GO:0007448 |... mutant phenotype <> regulation of transcription from RNA polymerase II promoter ; GO:0006357 |... mutant phenotype <> protein phosphorylation ; GO:0006468 | non-traceable author statement <> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <> regulation of cell differentiation ; GO:0045595 |... mutant phenotype <> neuromuscular synaptic transmission ; GO:0007274 |... mutant phenotype <> dorsal closure ; GO:0007391 | traceable author statement <> regulation of synaptic growth at neuromuscular junction ; GO:0008582 |... genetic interaction with Acsl <> transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification ; GO:0060799 |... mutant phenotype <> dorsal/ventral pattern formation ; GO:0009953 |... mutant phenotype inferred from genetic interaction with dpp <> heart development ; GO:0007507 | traceable author statement <> cell migration ; GO:0016477 |... mutant phenotype <> wing disc anterior/posterior pattern formation ; GO:0048100 |... mutant phenotype <> germ-line stem cell division ; GO:0042078 |... mutant phenotype <> regulation of imaginal disc growth ; GO:0045570 |... mutant phenotype <> open tracheal system development ; GO:0007424 |... mutant phenotype <> germ cell migration ; GO:0008354 |... mutant phenotype <> chorion-containing eggshell formation ; GO:0007304 |... genetic interaction with sax <> BMP signaling pathway ; GO:0030509 | traceable author statement <> morphogenesis of a branching structure ; GO:0001763 | non-traceable author statement <> positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 |... mutant phenotype <> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <> histoblast morphogenesis ; GO:0007488 |... mutant phenotype <> germ-line stem cell population maintenance ; GO:0030718 |... mutant phenotype <> anterior Malpighian tubule development ; GO:0061327 |... mutant phenotype <> decapentaplegic signaling pathway ; GO:0008101 |... mutant phenotype inferred from genetic interaction with dpp <> genital disc development ; GO:0035215 |... mutant phenotype <> open tracheal system development ; GO:0007424 | traceable author statement <> positive regulation of muscle organ development ; GO:0048636 |... mutant phenotype <> ovarian follicle cell development ; GO:0030707 | traceable author statement <> transforming growth factor beta receptor complex assembly ; GO:0007181 | non-traceable author statement <> cell elongation involved in imaginal disc-derived wing morphogenesis ; GO:0090254 |... mutant phenotype <> regulation of cell-cell adhesion ; GO:0022407 |... mutant phenotype <> negative regulation of gene expression ; GO:0010629 |... direct assay <> positive regulation of growth ; GO:0045927 |... mutant phenotype <> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity cytoneme ; GO:0035230 | colocalizes_with inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with babo cytosol ; GO:0005829 | inferred from direct assay multivesicular body ; GO:0005771 | inferred from direct assay presynapse ; GO:0098793 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "tkv, Tkv, TKV, CG14026, Brk25D2, Brk25D1, dtfr, Atkv, l(2)04415, str, Brk25D, l(2)25Da, STK-A, Dtfr, Atr25D, tkv1, kv, TKV1, tkva" "IPR000472:Activin types I and II receptor domain, IPR000719:Protein kinase domain, IPR003605:GS domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR000333:Ser/Thr protein kinase, TGFB receptor" CG14026 11-Aug-17 DroID_v2017_08 "Drer\bmpr1ab, Drer\bmpr1bb, Drer\acvrl1, Drer\bmpr1ba, Drer\LOC100331105, Drer\acvr1l, Drer\acvr1ba, Drer\tgfbr1b, Drer\tgfbr1a, Drer\bmpr1aa, Drer\acvr1bb" - "Cele\daf-1, Cele\sma-6" "Xtro\bmpr1b, Xtro\acvr1c, Xtro\brsk1, Xtro\acvr1b, Xtro\bmpr1a, Xtro\tgfbr1, Xtro\acvr1" "Mmus\Acvrl1, Mmus\Tgfbr1, Mmus\Acvr1c, Mmus\Acvr1, Mmus\Bmpr1b, Mmus\Acvr1b, Mmus\Bmpr1a" "Hsap\ACVRL1, Hsap\BMPR1B, Hsap\ACVR1C, Hsap\BMPR1A, Hsap\ACVR1B, Hsap\ACVR1, Hsap\TGFBR1" " embryonic stage | stage 16 , larval stage , embryonic stage , embryonic stage | stage 9 , embryonic stage | stage 1-4 , embryonic stage | syncytial blastoderm , embryonic stage | stage 6 , embryonic stage | stage 6,7 , embryonic stage | stage 13-16 , embryonic stage | early , embryonic stage | stage 7 , embryonic stage | stage 5 , embryonic stage | 0-12hr , embryonic stage | stage 6-9 , embryonic stage | stage 3,4 , embryonic stage | stage >=12 , embryonic stage | stage 11-12 , embryonic stage | stage 11 , embryonic stage | stage 10 , larval stage | third instar , adult stage && oogenesis stage , embryonic stage | stage >12 , embryonic stage | stage 8 , embryonic stage | stage 6-12 , embryonic stage | cellular blastoderm , embryonic stage | stage 12-17 " " gastric caecum

, imaginal disc

, organism

, midgut chamber 4

, morphogenetic furrow

, embryonic/larval proventriculus

, midgut chamber 1

, mesoderm

,

ubiquitous , dorsal mesothoracic disc

, organism | pair rule

, mesoderm | ventral

, posterior embryonic/larval midgut

, eye-antennal disc

, midgut constriction 1

, ectoderm | lateral

, ventral thoracic disc

, ectoderm | dorsal

, embryonic/larval pharynx

,

dorsal ventral gradient , posterior midgut proper primordium

, tracheal pit

, anterior midgut proper primordium

, tracheal primordium

, embryonic/larval hindgut

, dorsal mesothoracic disc | restricted

, nurse cell

, anterior embryonic/larval midgut

, visceral mesoderm

, ventral neurogenic region

, epidermis | dorsal

, centripetally migrating follicle cell

,

pair rule , embryonic/larval midgut

" "visible,dominant,viable,fertile,lethal,recessive,partially,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,wild-type,semidominant,heat sensitive,germline clone,neurophysiology defective,mitotic cell cycle defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,cold sensitive,cell lethalcell lethal,partially lethal - majority die,cell autonomous,maternal effect,RU486 conditional,increased cell number,cell non-autonomous,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,female sterile,cell shape defective,hyperplasia,female limited,sterile,male limited,circadian rhythm defective" "submarginal cell,1st posterior cell,,wing,wing vein,embryonic/first instar larval cuticle,sex comb,ventral thoracic disc,leg,bouton,neuromuscular junction,dorsal appendage,egg operculum,filzkorper,embryonic dorsal epidermis,dorsal triple row,medial triple row,ventral triple row,embryo,eye,wing disc,scutum,embryonic head,abdominal segment,eye disc,embryonic epidermis,peripodial epithelium,wing margin,anterior crossvein,posterior crossvein,cephalopharyngeal skeleton,midgut constriction,gastric caecum,trachea,embryonic/larval dorsal branch 1,embryonic/larval dorsal branch 2,embryonic/larval dorsal branch 3,embryonic/larval dorsal branch 4,embryonic/larval dorsal branch 5,embryonic/larval dorsal branch 6,embryonic/larval dorsal branch 7,embryonic/larval dorsal branch 8,embryonic/larval dorsal branch 9,embryonic/larval dorsal branch 10,ganglionic branch 0,ganglionic branch 1,ganglionic branch 2,ganglionic branch 3,ganglionic branch 4,ganglionic branch 5,ganglionic branch 6,ganglionic branch 7,ganglionic branch 8,ganglionic branch 9,embryonic/larval lateral trunk,embryonic/larval dorsal branch,embryonic/larval trachea,ommatidium,female germline stem cell,male germline stem cell,embryonic/larval tracheal system,stage 13 embryo,stage 14 embryo,stage 15 embryo,amnioserosa,filamentous actin,secondary pigment cell,adult midgut precursor cell,presumptive embryonic/larval peripheral nervous system,ventral nerve cord,adult thorax,genital disc primordium,synapse,t-bar,embryonic/larval dorsal vessel,crystal cell,Malpighian tubule,dorsal closure embryo,morphogenetic furrow,testis,abdominal ventral denticle belt,telson,visceral mesoderm,presumptive embryonic salivary gland,histoblast,histoblast nest,crossvein,air sac primordium |,scutellar bristle,wing blade,abdomen,mesothoracic extracoxal depressor muscle 66,thoracic adult muscle precursor cell,NMJ bouton,adult brain,macrochaeta,sensory mother cell,tsh-Gal4-1,hs.PB,wing cell,btl.PS,dorsal trunk primordium,btl.B123,embryonic/larval neuromuscular junction,egg chamber,tracheocyte,embryonic/larval dorsal trunk,dorsal branch primordium,embryonic/larval muscle system,embryonic/larval visceral branch,tracheal pit,wing pouch,genitalia,analia,wing margin bristle,apoptotic amnioserosa,germline cell,hub cell,pericardial cell,mesoderm,epidermal cell,cell cycle,wing disc |,ovary,cystoblast,2nd posterior cell,dil cell,wing sensillum,wing | prepupal stage,haltere,mesothoracic tergum,retina | pupal stage P6,adherens junction,inter-ommatidial precursor cell,germarium,female germline cell" FBgn0267562 CR45902 - http://flybase.org/reports/FBgn0267562 non_protein_coding_gene - - - CR45902 - CR45902 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267254 CG45690 - http://flybase.org/reports/FBgn0267254 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45690 - CG45690 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050377 CG30377 - http://flybase.org/reports/FBgn0050377 protein_coding_gene - copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype - "CG1918, CG14595, CG30377" - CG30377 11-Aug-17 DroID_v2017_08 Drer\cdk2ap2 - - "Xtro\cdk2ap2, Xtro\cdk2ap1" "Mmus\Cdk2ap1, Mmus\Cdk2ap2" "Hsap\CDK2AP2, Hsap\CDK2AP1" "viable,fertile,lethal" FBgn0022128 l(2)k06416 lethal (2) k06416 http://flybase.org/reports/FBgn0022128 - gene - - - l(2)k06416 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011062 l(1)Q15 lethal (1) Q15 http://flybase.org/reports/FBgn0011062 FBgn0010210 gene - - - l(1)Q15 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001540 l(1)14DEb lethal (1) 14DEb http://flybase.org/reports/FBgn0001540 - gene - - - "l(1)l, l(1)14DEb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062566 Mod(var)E69 Mod(var)E69 http://flybase.org/reports/FBgn0062566 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E69, Mod(var)E69" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,suppressor of variegation,viable" FBgn0019806 h::sc h::sc http://flybase.org/reports/FBgn0019806 - engineered_fusion_gene - - - h::sc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041582 tamo tamo http://flybase.org/reports/FBgn0041582 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 protein binding ; GO:0005515 | inferred from physical interaction with msl-1 inferred from physical interaction with mbo inferred from physical interaction with dl Ran GTPase binding ; GO:0008536 | inferred from physical interaction with Ran inferred from physical interaction with Ran-like multicellular organism development ; GO:0007275 | inferred from direct assay protein transport ; GO:0015031 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG4057, 60B, tamo" "IPR001876:Zinc finger, RanBP2-type, IPR029746:Protein tamozhennic, IPR018997:PUB domain" CG4057 11-Aug-17 DroID_v2017_08 "Drer\spata2l, Drer\spata2, Drer\si:ch211-189a15.5" - - Xtro\spata2 "Mmus\Spata2l, Mmus\Spata2" "Hsap\SPATA2, Hsap\SPATA2L" "female sterile,lethal,partially,viable" "embryonic dorsal epidermis,filzkorper,denticle belt,egg chamber" FBgn0010278 Ssrp Structure specific recognition protein http://flybase.org/reports/FBgn0010278 FBgn0005644 protein_coding_gene nucleosome binding ; GO:0031491 | inferred from direct assay protein self-association ; GO:0043621 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Trl nucleosomal DNA binding ; GO:0031492 | inferred from direct assay regulation of chromatin assembly or disassembly ; GO:0001672 | inferred from mutant phenotype regulation of DNA binding ; GO:0051101 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of protein phosphorylation ; GO:0001933 | inferred from mutant phenotype positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype FACT complex ; GO:0035101 | inferred from direct assay FACT complex ; GO:0035101 | traceable author statement nucleolus ; GO:0005730 | inferred from direct assay "ssrp, SSRP1, dSSRP1, SSRP, dSSRP, DssRP, Cf5, CG4817, Ssrp, dSsrp" "IPR013719:Domain of unknown function DUF1747, IPR024954:SSRP1 domain, IPR000969:Structure-specific recognition protein, IPR009071:High mobility group box domain, IPR011993:PH domain-like" CG4817 11-Aug-17 DroID_v2017_08 "Drer\ssrp1b, Drer\ssrp1a" "Scer\NHP6A, Scer\RTT106, Scer\NHP6B, Scer\POB3" "Cele\hmg-4, Cele\hmg-1.2, Cele\hmg-3" Xtro\ssrp1 Mmus\Ssrp1 Hsap\SSRP1 " oogenesis stage && adult stage | female , adult stage && oogenesis stage " " ovary

, nurse cell

" "lethal - all die during pharate adult stage,lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "eye,antenna,head capsule,eye-antennal disc,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC04658 IE -3.67644009 -3.621707834 -1.920941941 -2.251911414 0.210811842 -0.555188344 FBgn0030945 Ing3 "Inhibitor of growth family, member 3" http://flybase.org/reports/FBgn0030945 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone exchange ; GO:0043486 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay "dIng3~, dIng3, CG6632, Ing3, ING3" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR024610:Inhibitor of growth protein, N-terminal histone-binding, IPR028651:ING family, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6632 11-Aug-17 DroID_v2017_08 "Drer\ing2, Drer\taf3, Drer\ing1, Drer\ing5a, Drer\ing5b, Drer\ing3, Drer\ing4" "Scer\YNG1, Scer\YNG2, Scer\PHO23" "Cele\Y43H11AL.1, Cele\ing-3, Cele\lsy-13" "Xtro\ing5, Xtro\ing3, Xtro\taf3, Xtro\ing2, Xtro\ing1" "Mmus\Ing2, Mmus\Taf3, Mmus\Ing5, Mmus\Ing1, Mmus\Ing3, Mmus\Ing4" "Hsap\ING1, Hsap\TAF3, Hsap\ING5, Hsap\ING4, Hsap\ING3, Hsap\ING2" "viable,fertile" DRSC27959 EK -0.20937189 0.121195181 2.591371594 -0.420961652 -1.723706771 -1.52375965 FBgn0065566 l(2)SH0978 lethal (2) SH0978 http://flybase.org/reports/FBgn0065566 gene - - - "l(2)SH0978, l(2)SH2 0978" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041123 l(2)45Bd lethal (2) 45Bd http://flybase.org/reports/FBgn0041123 gene - - - l(2)45Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0000027 acj3 abnormal chemosensory jump 3 http://flybase.org/reports/FBgn0000027 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,recessive" FBgn0004593 Eig71Ef Ecdysone-induced gene 71Ef http://flybase.org/reports/FBgn0004593 - protein_coding_gene - autophagic cell death ; GO:0048102 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model "L71, L71-5, V, gene V, gene-V, CG7599, Eig71Ef, EIG71-EF" IPR003475:Insect protein of unknown function CG7599 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030679 CG8206 - http://flybase.org/reports/FBgn0030679 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007853 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein stabilization ; GO:0050821 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 CG8206 "IPR007853:Zinc finger, DNL-type, IPR024158:Mitochondrial import protein TIM15" CG8206 11-Aug-17 DroID_v2017_08 "Drer\card9, Drer\card11, Drer\dnlz, Drer\card14" Scer\ZIM17 Cele\F53A3.7 "Xtro\card9, Xtro\card14, Xtro\dnlz" "Mmus\Card10, Mmus\Card9, Mmus\Card14, Mmus\Card11, Mmus\Dnlz" "Hsap\CARD9, Hsap\CARD10, Hsap\CARD14, Hsap\DNLZ" viable FBgn0053434 5SrRNA:CR33434 5SrRNA:CR33434 http://flybase.org/reports/FBgn0053434 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33434, 5SrRNA:CR33434" - CR33434 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259624 B0621 - http://flybase.org/reports/FBgn0259624 gene - - - B0621 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0083270 E(smoDN)2640 Enhancer of smoDN 2640 http://flybase.org/reports/FBgn0083270 gene - - - E(smoDN)2640 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033935 Sin1 SAPK-interacting protein 1 http://flybase.org/reports/FBgn0033935 protein_coding_gene "phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 protein kinase binding ; GO:0019901 | inferred from sequence or structural similarity with UniProtKB:Q9BPZ7" stress-activated protein kinase signaling cascade ; GO:0031098 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 establishment or maintenance of actin cytoskeleton polarity ; GO:0030950 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 regulation of protein phosphorylation ; GO:0001932 | inferred from mutant phenotype TORC2 signaling ; GO:0038203 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype stress granule assembly ; GO:0034063 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype inferred from genetic interaction with Rheb "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 TORC2 complex ; GO:0031932 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 TORC2 complex ; GO:0031932 | inferred from sequence or structural similarity with HGNC:18752,PomBase:SPAPYUG7.02c" "Sin1, CG10105, dSin1, sin1" "IPR008828:TORC2 component Sin1/Avo1, IPR032679:Sin1, N-terminal, IPR031313:SAPK-interacting protein 1, Pleckstrin-homology domain, IPR031567:Sin1, middle CRIM domain" CG10105 11-Aug-17 DroID_v2017_08 Drer\mapkap1 Scer\AVO1 Cele\sinh-1 Xtro\mapkap1 Mmus\Mapkap1 Hsap\MAPKAP1 "viable,fertile,neuroanatomy defective,cell autonomous,somatic clone,small body" "class IV dendritic arborizing neuron,cell autonomous,somatic clone,dendrite | cell autonomous | somatic clone,ventral multidendritic neuron vdaB,abdominal anterior ventral multidendritic neuron vdaa,dorsal multidendritic neuron ddaC,embryonic/larval neuromuscular junction,wing" FBgn0051992 gw gawky http://flybase.org/reports/FBgn0051992 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z7K9 inferred from physical interaction with UniProtKB:A8DY81 inferred from physical interaction with UniProtKB:E1JHY7 inferred from physical interaction with UniProtKB:Q7K126 inferred from physical interaction with UniProtKB:Q8IMX1 inferred from physical interaction with UniProtKB:Q94547 inferred from physical interaction with UniProtKB:Q95RR8 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q32KD4 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P21187 "miRNA mediated inhibition of translation ; GO:0035278 | inferred from electronic annotation with InterPro:IPR033503 gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from mutant phenotype regulation of protein localization ; GO:0032880 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from direct assay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | NOT inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype" cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay "CG31992, CG9905, anon-EST:Posey205, CG11484, gw, GW182, dGW182, Gw, GW, gw182, GQ182, Gw182" "IPR019486:Argonaute hook domain, IPR015940:Ubiquitin-associated domain, IPR000504:RNA recognition motif domain, IPR026805:GW182, middle domain, IPR009060:UBA-like, IPR033503:Protein Gawky" CG31992 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-46g23.1, Drer\tnrc6c1, Drer\tnrc6c2, Drer\tnrc6b, Drer\si:dkey-217f16.6" "Scer\UBX6, Scer\UBX7" - "Xtro\tnrc6b, Xtro\tnrc6c" "Mmus\Tnrc6a, Mmus\Tnrc6b, Mmus\Tnrc6c" "Hsap\TNRC6B, Hsap\TNRC6C, Hsap\TNRC6A, Hsap\ADSL" "viable,locomotor rhythm defective,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC17135 IK 0.665496524 2.6419268 0.618447345 -1.189217022 1.748463007 1.393845439 FBgn0260108 2L3047 - http://flybase.org/reports/FBgn0260108 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L3047 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0085302 CG34273 - http://flybase.org/reports/FBgn0085302 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34273 - CG34273 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050099 CG30099 - http://flybase.org/reports/FBgn0050099 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7750, CG30099" - CG30099 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032477 CG5287 - http://flybase.org/reports/FBgn0032477 protein_coding_gene phospho-N-acetylmuramoyl-pentapeptide-transferase activity ; GO:0008963 | inferred from electronic annotation with InterPro:IPR000715 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity ; GO:0003975 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 dolichyl diphosphate biosynthetic process ; GO:0006489 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 protein N-linked glycosylation ; GO:0006487 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 "CG5287, dAlg7" "IPR033895:UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase, IPR000715:Glycosyl transferase, family 4" CG5287 11-Aug-17 DroID_v2017_08 Drer\dpagt1 Scer\ALG7 "Cele\D1005.2, Cele\algn-7" Xtro\dpagt1 Mmus\Dpagt1 Hsap\DPAGT1 FBgn0015405 l(1)11Fc lethal (1) 11Fc http://flybase.org/reports/FBgn0015405 - gene - - - l(1)11Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,semidominant,cold sensitive" FBgn0038058 CG5608 - http://flybase.org/reports/FBgn0038058 protein_coding_gene - regulation of lipid kinase activity ; GO:0043550 | inferred from electronic annotation with InterPro:IPR026825 lateral inhibition ; GO:0046331 | inferred from mutant phenotype PAS complex ; GO:0070772 | inferred from electronic annotation with InterPro:IPR026825 "CG5608, Vac14" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR032878:Vacuole morphology and inheritance protein 14, Fab1-binding region, IPR026825:Vacuole morphology and inheritance protein 14, IPR021841:Vacuolar protein 14 C-terminal Fig4-binding domain" CG5608 11-Aug-17 DroID_v2017_08 Drer\vac14 Scer\VAC14 Cele\vacl-14 Xtro\vac14 Mmus\Vac14 Hsap\VAC14 "viable,fertile,visible" "chaeta,supernumerary,wing" DRSC15841 K 0.163739503 0.097698181 0.201557391 0.226853992 1.873373894 -0.169285038 FBgn0043069 MESK4 Misexpression suppressor of KSR 4 http://flybase.org/reports/FBgn0043069 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with ksr inferred from genetic interaction with Ras85D cellular_component ; GO:0005575 | no biological data available "CG31447, BcDNA:LD15753, MESK4" "IPR032675:Leucine-rich repeat domain, L domain-like" CG31447 11-Aug-17 DroID_v2017_08 "Drer\LOC100331330, Drer\c13h10orf11" - Cele\T19D7.6 Xtro\c10orf11 Mmus\1700112E06Rik Hsap\C10orf11 viable FBgn0053283 CR33283 - http://flybase.org/reports/FBgn0053283 pseudogene_attribute - - - "CG33283, CR33283" - CR33283 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029903 pod1 pod1 http://flybase.org/reports/FBgn0029903 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from direct assay actin filament binding ; GO:0051015 | inferred from direct assay protein binding, bridging ; GO:0030674 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity" AMPA glutamate receptor clustering ; GO:0097113 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from electronic annotation with InterPro:IPR027331 actin filament ; GO:0005884 | colocalizes_with inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay cytoplasmic microtubule ; GO:0005881 | colocalizes_with inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay "CG4532, Dpod1, BEST:LD37601, BcDNA:LD08951, pod1, dmPod, coronin, POD-1, Pod1, pod-1" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR015505:Coronin, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR027331:Coronin 7, IPR011042:Six-bladed beta-propeller, TolB-like, IPR015048:Domain of unknown function DUF1899, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG4532 11-Aug-17 DroID_v2017_08 "Drer\coro7, Drer\LOC100537938" Scer\CRN1 Cele\pod-1 Xtro\coro7 Mmus\Coro7 "Hsap\CORO7-PAM16, Hsap\CORO7" "viable,fertile,cell shape defective" "intersegmental nerve,segmental nerve,ventral nerve cord,longitudinal connective,commissure" FBgn0032075 Tsp29Fb Tetraspanin 29Fb http://flybase.org/reports/FBgn0032075 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "CG9496, Dm.Tsp29Fb, anon-EST:ParkEST130, Tsp29Fb" "IPR018499:Tetraspanin/Peripherin, IPR000048:IQ motif, EF-hand binding site, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG9496 11-Aug-17 DroID_v2017_08 "Drer\tspan18a, Drer\upk1a, Drer\cd63, Drer\tspan9b, Drer\tspan9a, Drer\tspan7, Drer\tspan35, Drer\tspan18b, Drer\tspan34, Drer\tspan4b, Drer\tspan4a, Drer\tspan7b, Drer\zgc:64051, Drer\tspan37" - "Cele\tsp-8, Cele\tsp-11, Cele\tsp-13, Cele\tsp-6, Cele\tsp-19, Cele\tsp-5, Cele\tsp-7, Cele\tsp-10, Cele\tsp-4" "Xtro\cd63, Xtro\tspan6" "Mmus\Tspan9, Mmus\Tspan7, Mmus\Upk1a, Mmus\Tspan8, Mmus\Tspan18, Mmus\Tspan1, Mmus\Cd53, Mmus\Cd63, Mmus\Upk1b, Mmus\Tspan4, Mmus\Tspan6" "Hsap\CD63, Hsap\TSPAN8, Hsap\TSPAN6, Hsap\TSPAN18, Hsap\TSPAN4, Hsap\CD53, Hsap\TSPAN1, Hsap\TSPAN9, Hsap\TSPAN16, Hsap\UPK1A, Hsap\UPK1B, Hsap\TSPAN7" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002137 l(2)K234 lethal (2) K234 http://flybase.org/reports/FBgn0002137 - gene - - - l(2)K234 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033872 CG6329 - http://flybase.org/reports/FBgn0033872 protein_coding_gene - - - CG6329 - CG6329 11-Aug-17 DroID_v2017_08 - - "Cele\K11H12.6, Cele\F35C5.11, Cele\C15H9.9, Cele\K11H12.7" - - - viable FBgn0011949 tRNA:Arg-TCG-3-2 transfer RNA:Arginine-TCG 3-2 http://flybase.org/reports/FBgn0011949 "FBgn0011947, FBgn0052620, FBgn0060081" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna5-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-c, CR32620, tRNA:arg12Eb, chrX.trna9-ArgTCG, tRNA-Arg-TCG-3-2, tRNA:Arg-TCG-3-2, tRNA:R:12Eb, CGA" - CR32620 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014935 anon-92Ea anon-92Ea http://flybase.org/reports/FBgn0014935 - gene - - - anon-92Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051355 CG31355 - http://flybase.org/reports/FBgn0051355 protein_coding_gene - - - CG31355 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004425 LysB Lysozyme B http://flybase.org/reports/FBgn0004425 FBgn0002575 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 lysozyme activity ; GO:0003796 | inferred from sequence or structural similarity - - "LysB, lysB, CG1179, Lys B" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CG1179 11-Aug-17 DroID_v2017_08 "Drer\LOC100536671, Drer\lyz, Drer\LOC100334363" - - Xtro\MGC89221 "Mmus\Lyz2, Mmus\Lyzl1, Mmus\Lalba, Mmus\Spaca1, Mmus\Spaca7, Mmus\Spaca5, Mmus\Lyzl6, Mmus\Lyz1, Mmus\1700016D06Rik, Mmus\Lyzl4, Mmus\9530003J23Rik, Mmus\Spaca3, Mmus\Spaca4" "Hsap\SPACA5, Hsap\SPACA1, Hsap\LALBA, Hsap\SPACA3, Hsap\SPACA4, Hsap\SPACA7, Hsap\LYZL1, Hsap\LYZL4, Hsap\LYZ, Hsap\LYZL6, Hsap\SPACA5B, Hsap\LYZL2" " adult stage , larval stage && adult stage , larval stage " " adult midgut

, embryonic/larval midgut

" FBgn0002260 l(3)68Fe lethal (3) 68Fe http://flybase.org/reports/FBgn0002260 - gene - - - "rsg22, l(3)rsg22, l(3)68Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003648 Su(z)7 Suppressor of zeste 7 http://flybase.org/reports/FBgn0003648 - gene - - - Su(z)7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced" FBgn0267411 CG45764 - http://flybase.org/reports/FBgn0267411 protein_coding_gene - - - "CG45764, Mst77Y" - CG45764 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032624 CG6304 - http://flybase.org/reports/FBgn0032624 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.248, CG6304" "IPR009818:Ataxin-2, C-terminal" CG6304 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085831 CR42201 - http://flybase.org/reports/FBgn0085831 pseudogene_attribute - - - CR42201 - CR42201 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260317 GSd225 - http://flybase.org/reports/FBgn0260317 gene - - - GSd225 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001626 l(1)dn3 lethal (1) discs normal 3 http://flybase.org/reports/FBgn0001626 - gene - - - "l(1)d.norm.-3, l(1)dn3" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0054021 CG34021 - http://flybase.org/reports/FBgn0054021 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1044, CG34021" - CG34021 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002330 l(3)87Ab lethal (3) 87Ab http://flybase.org/reports/FBgn0002330 - gene - - - "ck9, l(3)ck9, l(3)87Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die" FBgn0015889 anon-75Ca anon-75Ca http://flybase.org/reports/FBgn0015889 - gene - - - anon-75Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032086 CG17906 - http://flybase.org/reports/FBgn0032086 protein_coding_gene - - - CG17906 - CG17906 11-Aug-17 DroID_v2017_08 - - "Cele\C46E10.2, Cele\srd-56" - - - viable FBgn0265603 AP-2mu::stnB - http://flybase.org/reports/FBgn0265603 engineered_fusion_gene - - - "AP-2mu::stnB, STNB-AP50, STNB-mu2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014351 ms(2)HB54 ms(2)HB54 http://flybase.org/reports/FBgn0014351 - gene - - - ms(2)HB54 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023063 l(1)2Dj lethal (1) 2Dj http://flybase.org/reports/FBgn0023063 - gene - - - "B3/52.19, 800F24, 800D22, l(1)2Dj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028575 pp20 pp20 http://flybase.org/reports/FBgn0028575 gene - - - pp20 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035768 CG14834 - http://flybase.org/reports/FBgn0035768 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT34650, CG14834" - CG14834 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065441 l(2)SH1458 lethal (2) SH1458 http://flybase.org/reports/FBgn0065441 gene - - - l(2)SH1458 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011377 l(3)j5B2 lethal (3) j5B2 http://flybase.org/reports/FBgn0011377 - gene - - - l(3)j5B2 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0043991 Su(rst)D63 Su(rst)D63 http://flybase.org/reports/FBgn0043991 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D63, Su(rst)D63" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022740 HLH54F HLH54F http://flybase.org/reports/FBgn0022740 FBgn0020923 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with MGI:MGI:1202715" visceral muscle development ; GO:0007522 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:1202715 inferred from sequence or structural similarity with MGI:MGI:1333884 "bHLH54F, HLH102C, CG5005, HLH54F, bHLHa9, HLH54F-Dm" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG5005 11-Aug-17 DroID_v2017_08 "Drer\tcf24, Drer\hand2, Drer\tal1, Drer\tcf15, Drer\tcf23, Drer\tcf21, Drer\tal2, Drer\figla, Drer\mespab, Drer\mespba, Drer\nhlh2, Drer\msgn1, Drer\scxa, Drer\si:ch211-246m6.4, Drer\ascl1a, Drer\ptf1a, Drer\lyl1, Drer\msc, Drer\ascl1b, Drer\scxb, Drer\mespaa" - "Cele\ngn-1, Cele\hlh-10, Cele\cnd-1" "Xtro\nhlh1, Xtro\scx, Xtro\lyl1, Xtro\hand1, Xtro\tcf15, Xtro\ascl2, Xtro\msc, Xtro\tcf21, Xtro\hand2, Xtro\figla, Xtro\mespb, Xtro\ptf1a, Xtro\msgn1, Xtro\mespa, Xtro\ascl3, Xtro\tal1" "Mmus\Tcf23, Mmus\Tal2, Mmus\Ferd3l, Mmus\Lyl1, Mmus\Hand1, Mmus\Msgn1, Mmus\Tcf15, Mmus\Nhlh1, Mmus\Ascl4, Mmus\Nhlh2, Mmus\Msc, Mmus\Scx, Mmus\Tcf24, Mmus\Mesp2, Mmus\Ascl1, Mmus\Figla, Mmus\Ascl5, Mmus\Ptf1a, Mmus\Ascl3, Mmus\Tal1, Mmus\Tcf21, Mmus\Hand2, Mmus\Mesp1" "Hsap\HAND2, Hsap\TCF24, Hsap\TCF23, Hsap\LYL1, Hsap\TCF15, Hsap\TCF21, Hsap\SCX, Hsap\PTF1A, Hsap\ASCL1, Hsap\NHLH2, Hsap\MESP1, Hsap\ASCL5, Hsap\FIGLA, Hsap\MSGN1, Hsap\NHLH1, Hsap\MESP2, Hsap\MSC, Hsap\TAL2, Hsap\ASCL3, Hsap\TAL1, Hsap\ASCL4, Hsap\HAND1" embryonic stage " somatic mesoderm | restricted

, visceral mesoderm | precursor

, visceral mesoderm

" "partially lethal - majority die,increased cell death,lethal,viable,visible" "longitudinal muscle,longitudinal visceral muscle primordium,longitudinal visceral muscle fiber,midgut muscle,cardioblast,embryonic somatic muscle,mesothoracic tergum" FBgn0051158 Efa6 Exchange factor for Arf 6 http://flybase.org/reports/FBgn0051158 protein_coding_gene ARF guanyl-nucleotide exchange factor activity ; GO:0005086 | inferred from electronic annotation with InterPro:IPR000904 phospholipid binding ; GO:0005543 | inferred from electronic annotation with InterPro:IPR001605 regulation of ARF protein signal transduction ; GO:0032012 | inferred from electronic annotation with InterPro:IPR000904 adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype regulation of ARF protein signal transduction ; GO:0032012 | inferred by curator from GO:0005086 adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay "EFA6, CG6941, CG18185, CG31158, Efa6, dPsd, dEfa6" "IPR000904:Sec7 domain, IPR001605:Pleckstrin homology domain, spectrin-type, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR023394:Sec7 domain, alpha orthogonal bundle, IPR032675:Leucine-rich repeat domain, L domain-like, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical, IPR001478:PDZ domain" CG31158 11-Aug-17 DroID_v2017_08 "Drer\psd3l, Drer\psd2, Drer\LOC101886286, Drer\si:ch211-150i13.1" "Scer\BOI2, Scer\GEA2, Scer\GEA1, Scer\SYT1" Cele\efa-6 "Xtro\psd4, Xtro\psd3" "Mmus\Psd3, Mmus\Psd, Mmus\Psd2, Mmus\Psd4" "Hsap\PSD3, Hsap\PSD2, Hsap\PSD4, Hsap\PSD" "viable,fertile" FBgn0033592 CG13215 - http://flybase.org/reports/FBgn0033592 protein_coding_gene - - - CG13215 - CG13215 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC06337 E -0.22054764 0.872038881 1.702989349 0.66404377 -0.096001721 -0.428687673 FBgn0030805 wus wurst http://flybase.org/reports/FBgn0030805 protein_coding_gene - "liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype" early endosome ; GO:0005769 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG9089, l(1)G0162, wus" "IPR001623:DnaJ domain, IPR007829:TM2 domain" CG9089 11-Aug-17 DroID_v2017_08 "Drer\dnajb1b, Drer\dnajc22, Drer\dnajc18, Drer\dnajb4, Drer\dnajb1a, Drer\dnajb5, Drer\dnajb2, Drer\dnajb9a, Drer\dnajb12a, Drer\dnajb12b, Drer\dnajc9, Drer\dnajb14" "Scer\SIS1, Scer\HLJ1" "Cele\dnj-23, Cele\ZK858.5" "Xtro\dnajc22, Xtro\dnajb12, Xtro\dnajb1, Xtro\dnajb4, Xtro\dnajb2, Xtro\dnajb5, Xtro\dnajc18, Xtro\dnajb13, Xtro\dnajb6, Xtro\dnajb14, Xtro\dnajb9" "Mmus\Dnajb8, Mmus\Dnajb13, Mmus\Dnajc21, Mmus\Dnajb4, Mmus\Dnajc9, Mmus\Dnajb3, Mmus\Dnajb5, Mmus\Dnajb1, Mmus\Dnajb2, Mmus\Dnajc22, Mmus\Dnajb6, Mmus\Dnajc18, Mmus\Dnajb12, Mmus\Dnajb9, Mmus\Dnajb14, Mmus\Dnajb7" "Hsap\DNAJC18, Hsap\DNAJC9, Hsap\DNAJB1, Hsap\DNAJC22, Hsap\DNAJB4, Hsap\DNAJB12, Hsap\DNAJB14, Hsap\DNAJB8, Hsap\DNAJB5, Hsap\DNAJB7, Hsap\DNAJB13, Hsap\DNAJB2, Hsap\DNAJB9, Hsap\DNAJB6" "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal" "embryonic/larval tracheal system,temperature conditional,presumptive embryonic/larval tracheal system,apical plasma membrane & embryonic tracheal system" FBgn0030717 CG8931 - http://flybase.org/reports/FBgn0030717 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8931 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG8931 11-Aug-17 DroID_v2017_08 Drer\slc25a46 - Cele\slc-25A46 "Xtro\slc25a19, Xtro\slc25a46" Mmus\Slc25a46 Hsap\SLC25A46 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0052670 Rab9Fb Rab at 9Fb http://flybase.org/reports/FBgn0052670 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 "DmRabX3, CG2532, Rab9Fb, CG32670, RabX3" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG32670 11-Aug-17 DroID_v2017_08 "Drer\rab1bb, Drer\rab19, Drer\rab33a, Drer\rab43, Drer\rab1ab, Drer\rab35b, Drer\si:dkey-16l2.16, Drer\rab35a, Drer\zgc:171927, Drer\rab1aa, Drer\rab33ba, Drer\rabl6a, Drer\rab1ba, Drer\rabl6b, Drer\zgc:101559" "Scer\TEM1, Scer\YPT1" "Cele\rab-35, Cele\rab-28" "Xtro\rab19, Xtro\rab33b, Xtro\rabl6, Xtro\rab28, Xtro\rab1a, Xtro\rab33a" "Mmus\Rab33a, Mmus\Rab35, Mmus\Rab33b, Mmus\Rab43, Mmus\Rab1a, Mmus\Rab19, Mmus\Rab28, Mmus\Rab1b, Mmus\Rabl6" "Hsap\RAB33B, Hsap\RAB33A, Hsap\RAB1A, Hsap\RAB43, Hsap\RAB1B, Hsap\RAB28, Hsap\RABL6, Hsap\RAB35, Hsap\RAB19" FBgn0267022 CR45466 - http://flybase.org/reports/FBgn0267022 non_protein_coding_gene - - - CR45466 - CR45466 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051477 ATPsynepsilonL "ATP synthase, epsilon subunit-like" http://flybase.org/reports/FBgn0051477 protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000006192 ATPase activity ; GO:0016887 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000278562" proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P56381 ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000006192 "mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P56381 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000278562" "CG12810, CG31477, ATPE, ATPsynepsilonL" "IPR006721:ATP synthase, F1 complex, epsilon subunit, mitochondrial" CG31477 11-Aug-17 DroID_v2017_08 Drer\atp5e Scer\ATP15 "Cele\R05D3.6, Cele\ZC262.5, Cele\hpo-18" - Mmus\Atp5e Hsap\ATP5E "viable,visible" trichogen cell DRSC14548 I 0.814122734 -2.043220409 -0.492273682 -1.105919192 0.666402913 1.466715498 FBgn0002495 l(3)SG55 lethal (3) SG55 http://flybase.org/reports/FBgn0002495 - gene - - - "l(3)L36, l(3)SG55" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0038775 CG17199 - http://flybase.org/reports/FBgn0038775 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003767 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003767 - CG17199 IPR003767:Malate/L-lactate dehydrogenase CG17199 11-Aug-17 DroID_v2017_08 - - "Cele\VF13D12L.3, Cele\F36A2.3" - - - viable FBgn0000923 fs(1)ne10 female sterile (1) no eggs 10 http://flybase.org/reports/FBgn0000923 - gene - - - "ne10, fs(1)ne[10], fs(1)ne10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "dorsal appendage,chorion,endochorion,oocyte" FBgn0005724 l(1)TK134 lethal (1) TK134 http://flybase.org/reports/FBgn0005724 - gene - - - "l134, l(1)TK134" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260369 GSd205 - http://flybase.org/reports/FBgn0260369 gene - - - GSd205 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031412 CG16995 - http://flybase.org/reports/FBgn0031412 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR018244 extracellular region ; GO:0005576 | inferred from sequence model CG16995 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR018244:Allergen V5/Tpx-1-related, conserved site, IPR014044:CAP domain, IPR034113:Golgi-associated plant pathogenesis-related protein 1, SCP domain" CG16995 11-Aug-17 DroID_v2017_08 "Drer\crispld2, Drer\r3hdml, Drer\pi15a, Drer\glipr2l, Drer\im:7150988, Drer\pi15b, Drer\LOC100536500, Drer\glipr2, Drer\crispld1b, Drer\crispld1a, Drer\glipr1b, Drer\LOC101883528" "Scer\PRY2, Scer\PRY3, Scer\PRY1" "Cele\C07A4.3, Cele\vap-2, Cele\scl-1, Cele\F57B7.2, Cele\F09B9.5, Cele\D2062.1, Cele\scl-19" "Xtro\crispld2, Xtro\crisp3, Xtro\glipr2, Xtro\crisp2, Xtro\crisp1, Xtro\r3hdml, Xtro\MGC108118" "Mmus\Crispld1, Mmus\Glipr1, Mmus\Glipr1l2, Mmus\Crispld2, Mmus\Crisp2, Mmus\Crisp4, Mmus\Pi16, Mmus\R3hdml, Mmus\Pi15, Mmus\Crisp3, Mmus\Glipr2, Mmus\Glipr1l1, Mmus\Clec18a, Mmus\Crisp1" "Hsap\GLIPR1L2, Hsap\GLIPR1, Hsap\PI16, Hsap\CLEC18A, Hsap\CLEC18B, Hsap\R3HDML, Hsap\CRISPLD1, Hsap\CLEC18C, Hsap\CRISP1, Hsap\GLIPR2, Hsap\CRISPLD2, Hsap\GLIPR1L1, Hsap\PI15, Hsap\CRISP2" viable FBgn0266352 CR45001 - http://flybase.org/reports/FBgn0266352 non_protein_coding_gene - - - CR45001 - CR45001 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085574 CG41248 - http://flybase.org/reports/FBgn0085574 protein_coding_gene - - - CG41248 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060472 l(3)S112014 lethal (3) S112014 http://flybase.org/reports/FBgn0060472 gene - - - "1120/14, l(3)S112014" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0261267 CG42615 - http://flybase.org/reports/FBgn0261267 protein_coding_gene - - - "CG42615, gft" - CG42615 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060869 l(3)S047208 lethal (3) S047208 http://flybase.org/reports/FBgn0060869 gene - - - "0472/08, l(3)S047208" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267546 CR45886 - http://flybase.org/reports/FBgn0267546 non_protein_coding_gene - - - "CR45886, Mgn1717" - CR45886 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039215 CG6695 - http://flybase.org/reports/FBgn0039215 protein_coding_gene - - - CG6695 IPR019147:Suppressor of white apricot N-terminal domain CG6695 11-Aug-17 DroID_v2017_08 Drer\clasrp - "Cele\taf-3, Cele\F28C1.1" Xtro\clasrp Mmus\Clasrp Hsap\CLASRP "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0052804 CG32804 - http://flybase.org/reports/FBgn0052804 protein_coding_gene - - - CG32804 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21314 I 0.926660174 -1.842050949 0.210266771 -0.020597241 0.431697099 0.079495767 FBgn0052248 CG32248 - http://flybase.org/reports/FBgn0052248 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32248 IPR004011:GYR motif CG32248 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0264944 CR44113 - http://flybase.org/reports/FBgn0264944 non_protein_coding_gene - - - CR44113 - CR44113 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065619 l(2)SH0806 lethal (2) SH0806 http://flybase.org/reports/FBgn0065619 gene - - - "l(2)SH0806, l(2)SH2 0806" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260230 CG42504 - http://flybase.org/reports/FBgn0260230 protein_coding_gene - - - CG42504 - CG42504 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003047 pcv posterior crossvein http://flybase.org/reports/FBgn0003047 - gene - - - pcv - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0264414 FCE-G - http://flybase.org/reports/FBgn0264414 gene - - - FCE-G - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,somatic clone" FBgn0039223 CG5805 - http://flybase.org/reports/FBgn0039223 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of mitochondrial outer membrane ; GO:0031307 | inferred from biological aspect of ancestor with PANTHER:PTN000640716 CG5805 "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG5805 11-Aug-17 DroID_v2017_08 "Drer\slc25a44b, Drer\slc25a44a" "Scer\UGO1, Scer\AGC1" "Cele\F13G3.7, Cele\Y43C5B.3" Xtro\slc25a44 Mmus\Slc25a44 Hsap\SLC25A44 viable DRSC15878 E -0.347565075 -0.328281302 -1.978301092 0.295757719 0.179944278 -0.057406919 FBgn0263030 CG43325 - http://flybase.org/reports/FBgn0263030 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13514, CG30217, CG43325" - CG43325 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003096 Pearl Pearl http://flybase.org/reports/FBgn0003096 - gene - - - "Pl, Pearl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male fertile,reduced,lethal - all die before end of pupal stage,some die during pupal stage" "wing,heat sensitive,wing vein,eye,wing margin,macrochaeta,imaginal disc" FBgn0032322 CG16743 - http://flybase.org/reports/FBgn0032322 protein_coding_gene - - - "BcDNA:RH23514, CG16743" - CG16743 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029754 CG15930 - http://flybase.org/reports/FBgn0029754 protein_coding_gene - - - CG15930 IPR002999:Tudor domain CG15930 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065248 l(2)SH2136 lethal (2) SH2136 http://flybase.org/reports/FBgn0065248 gene - - - l(2)SH2136 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004039 yea5 yeast 5 http://flybase.org/reports/FBgn0004039 - gene - - - yea5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031836 CG11050 - http://flybase.org/reports/FBgn0031836 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern - "BcDNA:LD22339, CG11050" IPR006674:HD domain CG11050 11-Aug-17 DroID_v2017_08 Drer\hddc2 "Scer\YBR242W, Scer\YGL101W" Cele\F45F2.9 Xtro\hddc2 Mmus\Hddc2 Hsap\HDDC2 viable FBgn0001713 l(1)ESHS34 lethal (1) ESHS34 http://flybase.org/reports/FBgn0001713 - gene - - - l(1)ESHS34 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267708 CR46041 - http://flybase.org/reports/FBgn0267708 non_protein_coding_gene - - - CR46041 - CR46041 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036751 Adgf-B Adenosine deaminase-related growth factor B http://flybase.org/reports/FBgn0036751 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine deaminase activity ; GO:0004000 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "adenosine catabolic process ; GO:0006154 | inferred from sequence or structural similarity with Adgf-A, Adgf-D cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR006331, InterPro:IPR013659" "CG5998, ADGF-B, adgfb, Adgf-B, AdgfB" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG5998 11-Aug-17 DroID_v2017_08 "Drer\ada, Drer\adal, Drer\cecr1b, Drer\cecr1a" Scer\AAH1 - "Xtro\adal, Xtro\ada.2, Xtro\cecr1, Xtro\ada" "Mmus\Ada, Mmus\Adal" "Hsap\ADAL, Hsap\ADA, Hsap\CECR1" viable DRSC24118 K -0.369158908 -0.498485012 0.609054545 -0.203045716 1.555637884 0.143069404 FBgn0285879 disco-r disco-related http://flybase.org/reports/FBgn0285879 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype epithelial to mesenchymal transition ; GO:0001837 | inferred from mutant phenotype delamination ; GO:0060232 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "disco-r, bae, CG9223, CG9219, CG32577" IPR013087:Zinc finger C2H2-type CG32577 11-Aug-17 DroID_v2017_08 "Drer\bnc1, Drer\bnc2" - Cele\bnc-1 "Xtro\bnc1, Xtro\bnc2" "Mmus\Bnc2, Mmus\Bnc1" "Hsap\BNC2, Hsap\BNC1" "viable,fertile,visible,semidominant" "wing,cell non-autonomous" FBgn0044066 GT49-2-4 GT49-2-4 http://flybase.org/reports/FBgn0044066 gene - - - GT49-2-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0041000 CG15476 - http://flybase.org/reports/FBgn0041000 protein_coding_gene - - - "38D.5, CG15476" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC02487 IEK 1.516561193 0.629525125 2.00835376 -3.06981675 0.42644284 1.605097904 FBgn0043874 nad1 nurse cell apoptosis defective-1 http://flybase.org/reports/FBgn0043874 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "nad-1, nad1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036671 CG9951 - http://flybase.org/reports/FBgn0036671 protein_coding_gene cullin family protein binding ; GO:0097602 | inferred from biological aspect of ancestor with PANTHER:PTN000402481 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:2000060 | inferred from biological aspect of ancestor with PANTHER:PTN000402481 - CG9951 "IPR008530:Coiled-coil domain-containing protein 22, IPR015866:Serine-tRNA synthetase, type1, N-terminal" CG9951 11-Aug-17 DroID_v2017_08 Drer\ccdc22 - Cele\R08E3.3 Xtro\ccdc22 Mmus\Ccdc22 Hsap\CCDC22 viable FBgn0031842 Tango1 Transport and Golgi organization 1 http://flybase.org/reports/FBgn0031842 protein_coding_gene chaperone binding ; GO:0051087 | inferred from electronic annotation with InterPro:IPR003103 molecular_function ; GO:0003674 | no biological data available secretory granule organization ; GO:0033363 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype positive regulation of secretion ; GO:0051047 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum exit site ; GO:0070971 | inferred from direct assay Golgi cis cisterna ; GO:0000137 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG11098, TANGO1, Tango1, tango1" IPR003103:BAG domain CG11098 11-Aug-17 DroID_v2017_08 "Drer\mia, Drer\mia3, Drer\mia2" - - Xtro\ctage5 "Mmus\Spz1, Mmus\Mia2, Mmus\Otor, Mmus\Mia, Mmus\Mia3" "Hsap\CTAGE9, Hsap\MIA, Hsap\OTOR, Hsap\CTAGE8, Hsap\CTAGE6, Hsap\MIA3, Hsap\SPZ1, Hsap\CTAGE15, Hsap\CTAGE1, Hsap\CTAGE4, Hsap\MIA2" "lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval proventriculus outer layer,secretory granuleunspecified" DRSC27972 K -0.490480529 -0.238042993 -0.191774262 -0.468782202 -0.216851909 2.287234091 FBgn0034030 CG8192 - http://flybase.org/reports/FBgn0034030 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG8192 IPR002557:Chitin binding domain CG8192 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - viable DRSC07101 IE -1.118523549 -2.663406072 -0.335582856 -2.05762204 -0.293378602 -0.556071573 FBgn0031288 CG13949 - http://flybase.org/reports/FBgn0031288 protein_coding_gene - - - "BcDNA:AT06839, CG13949" - CG13949 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC00367 K 0.139036982 -0.592194996 -0.038950647 0.52576729 1.932551119 -0.115599557 FBgn0267461 CR45811 - http://flybase.org/reports/FBgn0267461 non_protein_coding_gene - - - CR45811 - CR45811 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020442 Eric Ecdysone receptor interacting co-repressor http://flybase.org/reports/FBgn0020442 - gene - - cellular_component ; GO:0005575 | no biological data available Eric - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038666 Smu1 Smu1 spliceosomal factor http://flybase.org/reports/FBgn0038666 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Smu1, CG5451, dsmu1" "IPR001680:WD40 repeat, IPR006594:LIS1 homology motif, IPR006595:CTLH, C-terminal LisH motif, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG5451 11-Aug-17 DroID_v2017_08 "Drer\smu1a, Drer\smu1b" "Scer\PRP46, Scer\UTP13" "Cele\smu-1, Cele\dyci-1" Xtro\smu1 Mmus\Smu1 Hsap\SMU1 "neuroanatomy defective,neurophysiology defective,viable" NMJ bouton FBgn0267471 CR45821 - http://flybase.org/reports/FBgn0267471 non_protein_coding_gene - - - CR45821 - CR45821 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001591 l(1)carot8 lethal (1) carot8 http://flybase.org/reports/FBgn0001591 - gene - - - l(1)carot8 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001726 l(1)ESHS47 lethal (1) ESHS47 http://flybase.org/reports/FBgn0001726 - gene - - - l(1)ESHS47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020595 anon-57Cb anon-57Cb http://flybase.org/reports/FBgn0020595 - gene - - - anon-57Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039673 CG7568 - http://flybase.org/reports/FBgn0039673 protein_coding_gene - - intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN001483500 CG7568 "IPR019775:WD40 repeat, conserved site, IPR001680:WD40 repeat, IPR020472:G-protein beta WD-40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7568 11-Aug-17 DroID_v2017_08 "Drer\prpf4, Drer\daw1, Drer\fbxw11a, Drer\fbxw7, Drer\fbxw11b, Drer\wdr5, Drer\ahi1" "Scer\CDC4, Scer\MET30, Scer\PRP4" "Cele\sel-10, Cele\wdr-5.1, Cele\Y44F5A.1, Cele\lin-23" "Xtro\btrc, Xtro\fbxw7, Xtro\prpf4, Xtro\daw1" "Mmus\Fbxw11, Mmus\Fbxw7, Mmus\Ahi1, Mmus\Daw1, Mmus\Btrc, Mmus\Wdr5, Mmus\Wdr5b, Mmus\Prpf4" "Hsap\WDR5B, Hsap\FBXW11, Hsap\DAW1, Hsap\PRPF4, Hsap\BTRC, Hsap\WDR5, Hsap\FBXW7, Hsap\AHI1" viable FBgn0040324 Ephrin Ephrin http://flybase.org/reports/FBgn0040324 protein_coding_gene ephrin receptor binding ; GO:0046875 | inferred from direct assay melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay "CG1862, Ephrin, lincRNA.922, ephrin" "IPR001799:Ephrin receptor-binding domain, IPR008972:Cupredoxin, IPR031328:Ephrin" CG1862 11-Aug-17 DroID_v2017_08 "Drer\efnb2a, Drer\efnb2b, Drer\efna3a, Drer\LOC100332852, Drer\efnb3a, Drer\efna1b, Drer\efna3b, Drer\efna1a, Drer\efna5a, Drer\efna2a, Drer\efnb1, Drer\efnb3b, Drer\efna5b" - "Cele\vab-2, Cele\efn-2, Cele\efn-4, Cele\efn-3" "Xtro\efna1, Xtro\efnb2, Xtro\efna2, Xtro\efna3, Xtro\efnb1, Xtro\efna5" "Mmus\Efnb3, Mmus\Efna4, Mmus\Efna2, Mmus\Efna3, Mmus\Efna1, Mmus\Efnb1, Mmus\Efna5, Mmus\Efnb2" "Hsap\EFNA4, Hsap\EFNA3, Hsap\EFNA5, Hsap\EFNB1, Hsap\EFNA2, Hsap\EFNA1, Hsap\EFNB2, Hsap\EFNB3" " embryonic stage | stage 4-5 , embryonic stage | stage 13 , embryonic stage | late , embryonic stage | gastrula , " "

, ventral ectoderm && embryonic somatic muscle | ventral && embryonic central nervous system | restricted

, central nervous system | restricted

, mesoderm | restricted

, cell

" "neuroanatomy defective,somatic clone,viable,recessive,fertile,immune response defective,visible" "adult antennal lobe projection neuron,somatic clone,mushroom body alpha-lobe,presumptive embryonic/larval central nervous system,commissure,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,eye,medulla neuropil,lobula,longitudinal connective,embryonic/larval neuron" FBgn0266215 CR44910 - http://flybase.org/reports/FBgn0266215 non_protein_coding_gene - - - CR44910 - CR44910 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020344 anon-51Ba anon-51Ba http://flybase.org/reports/FBgn0020344 - gene - - - "514, anon-51Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021938 l(2)k10816 lethal (2) k10816 http://flybase.org/reports/FBgn0021938 - gene - - - l(2)k10816 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031041 CG12788 - http://flybase.org/reports/FBgn0031041 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG33066, CG12788, Dromel_CG12788_CG17767_FBtr0074_tim9b_mORF, PSTK" "IPR013641:Protein KTI12/L-seryl-tRNA(Sec) kinase, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12788 11-Aug-17 DroID_v2017_08 Drer\LOC101884223 - Cele\pstk-1 Xtro\pstk "Mmus\Timm10b, Mmus\Pstk" "Hsap\TIMM10B, Hsap\PSTK" FBgn0015320 Ubc2 Ubiquitin conjugating enzyme 2 http://flybase.org/reports/FBgn0015320 FBgn0021893 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000000286 inferred from sequence or structural similarity with SGD:S000002466 inferred from genetic interaction with SGD:S000000286 inferred from genetic interaction with SGD:S000002466 lipid storage ; GO:0019915 | inferred from direct assay protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with SGD:S000002466 cellular_component ; GO:0005575 | no biological data available "UbcD2, CG6720, ubcD2, l(2)k13206, Ubc2" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG6720 11-Aug-17 DroID_v2017_08 "Drer\ube2d2, Drer\ube2d1b, Drer\ube2na, Drer\ube2e2, Drer\ube2d4, Drer\ube2nb, Drer\ube2e1, Drer\ube2d1a, Drer\ube2d2l, Drer\ube2t, Drer\ube2e3, Drer\ube2d3" "Scer\PEX4, Scer\UBC13, Scer\UBC4, Scer\UBC5" Cele\let-70 "Xtro\ube2e1, Xtro\ube2d3, Xtro\ube2e3, Xtro\ube2e2, Xtro\ube2n, Xtro\ube2d1, Xtro\ube2d4" "Mmus\Ube2e1, Mmus\Ube2t, Mmus\Ube2dnl2, Mmus\Ube2n, Mmus\Ube2d3, Mmus\Ube2d2b, Mmus\Ube2d1, Mmus\Ube2e2, Mmus\Ube2d2a, Mmus\Ube2dnl1, Mmus\Ube2e3" "Hsap\UBE2D4, Hsap\UBE2E3, Hsap\UBE2T, Hsap\UBE2Q2L, Hsap\UBE2N, Hsap\UBE2E1, Hsap\UBE2D1, Hsap\UBE2D3, Hsap\UBE2NL, Hsap\UBE2E2, Hsap\UBE2D2" "lethal,recessive,neuroanatomy defective,somatic clone,visible,viable" "neuroblast,somatic clone,macrochaeta,scutellar bristle,tormogen cell,trichogen cell,ectopic,mesothoracic tergum" FBgn0025941 anon-89Bb anon-89Bb http://flybase.org/reports/FBgn0025941 - gene - - - "89B-ov3.5, anon-89Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage ovary

FBgn0062624 Mod(var)1126 Mod(var)1126 http://flybase.org/reports/FBgn0062624 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1126, Mod(var)1126" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,partially lethal - majority die" FBgn0052196 CG32196 - http://flybase.org/reports/FBgn0052196 protein_coding_gene gamma-glutamylcyclotransferase activity ; GO:0003839 | inferred from electronic annotation with InterPro:IPR017939 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32196 "IPR017939:Gamma-glutamylcyclotransferase, IPR013024:Gamma-glutamyl cyclotransferase-like" CG32196 11-Aug-17 DroID_v2017_08 "Drer\ggctb, Drer\ggcta" - Cele\C44B7.7 Xtro\ggct Mmus\Ggct Hsap\GGCT FBgn0004598 Fur2 Furin 2 http://flybase.org/reports/FBgn0004598 FBgn0042227 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from genetic interaction with Fur1 serine-type endopeptidase activity ; GO:0004252 | inferred from direct assay "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000209, InterPro:IPR002884 negative regulation of secretion ; GO:0051048 | inferred from genetic interaction with pgant4 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with Fur1 "154521_at, fur2, Furin, Dfur2, FUR2, DMH#11, furin, CG4235, CG18734, Fur2, Dfurin2" "IPR000209:Peptidase S8/S53 domain, IPR002884:Proprotein convertase, P, IPR006212:Furin-like repeat, IPR008979:Galactose-binding domain-like, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR009030:Growth factor receptor cysteine-rich domain, IPR015500:Peptidase S8, subtilisin-related, IPR032815:Peptidase S8, pro-domain, IPR032778:Growth factor receptor domain 4, IPR034182:Kexin/furin catalytic domain, IPR000494:Receptor L-domain, IPR000742:EGF-like domain, IPR022398:Peptidase S8, subtilisin, His-active site, IPR023827:Peptidase S8, subtilisin, Asp-active site, IPR023828:Peptidase S8, subtilisin, Ser-active site" CG18734 11-Aug-17 DroID_v2017_08 "Drer\pcsk7, Drer\pcsk5a, Drer\pcsk1, Drer\pcsk2, Drer\furinb, Drer\fras1, Drer\pcsk5b, Drer\LOC100330575, Drer\furina, Drer\rspo3" Scer\KEX2 "Cele\egl-3, Cele\aex-5, Cele\bli-4, Cele\kpc-1, Cele\F48E3.8" "Xtro\rspo3, Xtro\pcsk7, Xtro\pcsk5, Xtro\furin, Xtro\pcsk2, Xtro\pcsk6, Xtro\pcsk1, Xtro\fras1, Xtro\pcsk4" "Mmus\Pcsk1, Mmus\Pcsk5, Mmus\Rspo4, Mmus\Pcsk7, Mmus\Pcsk2, Mmus\Rspo3, Mmus\Rspo1, Mmus\Furin, Mmus\Fras1, Mmus\Pcsk4, Mmus\Pcsk6" "Hsap\PCSK4, Hsap\RSPO4, Hsap\PCSK1, Hsap\RSPO1, Hsap\FRAS1, Hsap\FURIN, Hsap\PCSK2, Hsap\PCSK6, Hsap\RSPO3, Hsap\PCSK5, Hsap\PCSK7" viable FBgn0038210 CG3199 - http://flybase.org/reports/FBgn0038210 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3199 IPR031992:Domain of unknown function DUF4788 CG3199 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265252 CR44266 - http://flybase.org/reports/FBgn0265252 non_protein_coding_gene - - - CR44266 - CR44266 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064165 l(3)Eq1 lethal (3) Eq1 http://flybase.org/reports/FBgn0064165 gene - - - l(3)Eq1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024887 kin17 kin17 http://flybase.org/reports/FBgn0024887 FBgn0036976 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN000301499 "DNA replication ; GO:0006260 | inferred from biological aspect of ancestor with PANTHER:PTN000301499 cellular response to DNA damage stimulus ; GO:0006974 | inferred from biological aspect of ancestor with PANTHER:PTN000301499 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG5649, kin17" "IPR019447:DNA/RNA-binding protein Kin17, conserved domain, IPR013087:Zinc finger C2H2-type" CG5649 11-Aug-17 DroID_v2017_08 Drer\kin Scer\RTS2 Cele\dxbp-1 Xtro\kin Mmus\Kin Hsap\KIN viable FBgn0030729 CG12507 - http://flybase.org/reports/FBgn0030729 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12507 - CG12507 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060540 l(3)S100108a lethal (3) S100108a http://flybase.org/reports/FBgn0060540 gene - - - "1001/08, l(3)S100108a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0284244 l(2)k05911 lethal (2) k05911 http://flybase.org/reports/FBgn0284244 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "l(2)k05911, SP36, c-SP36, CG16821, CG31728" "IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG31728 11-Aug-17 DroID_v2017_08 "Drer\ctrb1, Drer\si:ch211-165b19.8, Drer\si:dkey-78l4.13, Drer\tmprss5, Drer\f10, Drer\ela2l, Drer\ctrl, Drer\si:dkey-78l4.8, Drer\zgc:92511, Drer\plg, Drer\zgc:112302, Drer\zgc:112285, Drer\zgc:171592, Drer\zgc:154142, Drer\zgc:112160, Drer\ela3l, Drer\si:dkey-78l4.1, Drer\si:dkey-78l4.12, Drer\zgc:112368, Drer\zgc:92745, Drer\pik3ip1, Drer\si:dkey-78l4.2, Drer\ela2, Drer\f2, Drer\si:dkey-78l4.7, Drer\si:dkey-238d18.3, Drer\zgc:163025, Drer\zgc:92041, Drer\LOC562139, Drer\si:dkey-57c15.4, Drer\tmprss4b, Drer\proza, Drer\prozb, Drer\f9b, Drer\habp2, Drer\si:dkey-78l4.6, Drer\f9a, Drer\gzm3, Drer\si:dkey-33i11.3" - "Cele\try-9, Cele\try-1" "Xtro\LOC100135144, Xtro\cela3a, Xtro\LOC100489516, Xtro\LOC101733231, Xtro\ctrb1, Xtro\cela2a, Xtro\gzmh, Xtro\ctrb2" "Mmus\Gzme, Mmus\Cela3b, Mmus\Cela2a, Mmus\Ctrb1, Mmus\Cela3a, Mmus\Prss54, Mmus\Tmprss11b, Mmus\Ctrl, Mmus\Hpn, Mmus\Mcpt8, Mmus\Prss55, Mmus\Cela1, Mmus\Ctrc, Mmus\Pik3ip1" "Hsap\GZMM, Hsap\HPN, Hsap\CELA3A, Hsap\PRSS54, Hsap\CELA3B, Hsap\PIK3IP1, Hsap\CTRC, Hsap\PRSS57, Hsap\CMA1, Hsap\CTRL, Hsap\CELA1, Hsap\GZMA, Hsap\CELA2B, Hsap\CTSG, Hsap\CELA2A, Hsap\AZU1, Hsap\TPSD1, Hsap\PRSS55, Hsap\CTRB1, Hsap\TPSAB1, Hsap\CTRB2" FBgn0024858 l(3)96Bd lethal (3) 96Bd http://flybase.org/reports/FBgn0024858 - gene - - - l(3)96Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067100 H47 H47 http://flybase.org/reports/FBgn0067100 gene - - - H47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective,lethal" "chaeta,ommatidium,pigment cell" FBgn0060795 l(3)S058407 lethal (3) S058407 http://flybase.org/reports/FBgn0060795 gene - - - "0584/07, l(3)S058407" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267681 CR46017 - http://flybase.org/reports/FBgn0267681 non_protein_coding_gene - - - CR46017 - CR46017 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005439 l(1)v129 lethal (1) v129 http://flybase.org/reports/FBgn0005439 - gene - - - "l(1)129, l(1)v129" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263102 psq pipsqueak http://flybase.org/reports/FBgn0263102 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement sequence-specific DNA binding ; GO:0043565 | inferred from direct assay POZ domain binding ; GO:0031208 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 olfactory behavior ; GO:0042048 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype gene silencing ; GO:0016458 | traceable author statement regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | non-traceable author statement embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype" nucleus ; GO:0005634 | traceable author statement PcG protein complex ; GO:0031519 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "PSQ, CG2368, psq, Psq, rum, eyeful, BTB-V, pip, psq-1, psk, zep, BtbV, Piq, Pipsqueak" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR007889:DNA binding HTH domain, Psq-type, IPR009057:Homeobox domain-like" CG2368 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Nacc1, Mmus\Bach2, Mmus\Nacc2" Hsap\BACH2 " embryonic stage | 0-2 hr , embryonic stage | stage 5-8 , embryonic stage | late , larval stage | third instar , oogenesis stage , embryonic stage | stage 7-8 , embryonic stage | stage 5 " "

dorsal<&>anterior , maxillary segment

, photoreceptor cell R3 && photoreceptor cell R4

, eye-antennal disc | restricted

, ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, amnioserosa

, mandibular segment

, morphogenetic furrow | posterior to

, labial segment

,

20-70% egg length | dorsal " " adult stage && oogenesis stage | early , oogenesis stage | stage S10 && adult stage | female , larval stage " " germarium region 2a

, follicle cell

, eye-antennal disc | restricted

, dorsal mesothoracic disc

" FBgn0262903 CR43258 - http://flybase.org/reports/FBgn0262903 non_protein_coding_gene - - - "CR43258, lincRNA.813" - CR43258 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250753 kra krasavietz http://flybase.org/reports/FBgn0250753 protein_coding_gene translation initiation factor binding ; GO:0031369 | inferred from physical interaction with eIF2β ribosome binding ; GO:0043022 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with shot protein binding ; GO:0005515 | inferred from physical interaction with RpL5 ribosomal small subunit binding ; GO:0043024 | inferred from direct assay long-term memory ; GO:0007616 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype inferred from genetic interaction with shot long-term memory ; GO:0007616 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype axon ; GO:0030424 | inferred from direct assay filopodium ; GO:0030175 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay axonal growth cone ; GO:0044295 | inferred from direct assay "CG2922, Kra, ecp, eIF-5C, CT7240, elF-5C, Decp, l(3)03022, anon-WO0172774.49, eIf-5c, eIF, eiF-5C, l(3)j9B6, kra, eIF-5c, exba, eIF5c, Exba, elF5C, elf-5C, eIF5, ECP, chr3R:1423015..1423173, exba/kra, Ecp, 5MP" "IPR003307:W2 domain, IPR016024:Armadillo-type fold" CG2922 11-Aug-17 DroID_v2017_08 "Drer\bzw1b, Drer\bzw2, Drer\bzw1a" Scer\TIF5 Cele\C37C3.2 "Xtro\bzw2, Xtro\eif4g2, Xtro\bzw1" "Mmus\Bzw2, Mmus\Bzw1, Mmus\Eif5" "Hsap\BZW1, Hsap\EIF5, Hsap\BZW2" DRSC12320 IEK 0.332813796 -3.202455523 -1.511429492 1.449847694 -1.662290281 0.103800187 FBgn0036581 MED10 Mediator complex subunit 10 http://flybase.org/reports/FBgn0036581 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VS38 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR019145 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN000331217 mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from direct assay "Med10, Nut2, CG5057, dTRAP15, dMED10, BcDNA:SD24044, MED10, med10, l(3)72Ds" "IPR019145:Mediator complex, subunit Med10" CG5057 11-Aug-17 DroID_v2017_08 Drer\med10 "Scer\NUT2, Scer\BUD27" Cele\mdt-10 Xtro\med10 Mmus\Med10 Hsap\MED10 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC10474 EK -1.078593002 1.089935008 -2.440556108 -0.179582626 2.873923399 3.684931128 FBgn0039435 TwdlP TweedleP http://flybase.org/reports/FBgn0039435 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlP, CG14240" IPR004145:Domain of unknown function DUF243 CG14240 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage,viable" DRSC14734 I 1.976514686 0.081340687 0.619697568 -0.452202267 0.144693257 0.745605585 FBgn0036131 CG12522 - http://flybase.org/reports/FBgn0036131 protein_coding_gene - - - CG12522 - CG12522 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC09088 I 1.932882938 0.456025944 -1.08514863 0.028996724 0.287038533 0.108066761 FBgn0058337 CG40337 - http://flybase.org/reports/FBgn0058337 protein_coding_gene - - - CG40337 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20701 IE -1.561639011 -0.99108678 -0.683278749 3.12587321 -0.243989747 -0.154654799 FBgn0014075 Ugt UDP-glucose-glycoprotein glucosyltransferase http://flybase.org/reports/FBgn0014075 "FBgn0046358, FBgn0046359" protein_coding_gene UDP-glucose:glycoprotein glucosyltransferase activity ; GO:0003980 | inferred from direct assay protein glycosylation ; GO:0006486 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement rough endoplasmic reticulum ; GO:0005791 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay "GT, UGT, DUGT, CG6850, anon-WO0172774.75, anon-WO0172774.73, Ugt, UGGT, ugt" "IPR009448:UDP-glucose:Glycoprotein Glucosyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases, IPR002495:Glycosyl transferase, family 8" CG6850 11-Aug-17 DroID_v2017_08 "Drer\uggt1, Drer\uggt2" Scer\KRE5 "Cele\uggt-2, Cele\uggt-1" "Xtro\uggt2, Xtro\uggt1" "Mmus\Uggt1, Mmus\Uggt2" "Hsap\UGGT1, Hsap\UGGT2" " embryonic stage--pupal stage , embryonic stage "

ubiquitous " embryonic stage -- adult stage , adult stage && oogenesis stage " oocyte

viable FBgn0039739 RpS28a Ribosomal protein S28a http://flybase.org/reports/FBgn0039739 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000005693 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000289 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 cytoplasmic translation ; GO:0002181 | traceable author statement maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022627 wing disc development ; GO:0035220 | inferred from mutant phenotype cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with SGD:S000005693 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CG15527, RpS28a" "IPR000289:Ribosomal protein S28e, IPR012340:Nucleic acid-binding, OB-fold, IPR028626:Ribosomal protein S28e conserved site" CG15527 11-Aug-17 DroID_v2017_08 Drer\rps28 "Scer\RPS28A, Scer\RPS28B" Cele\rps-28 Xtro\rps28p9 Mmus\Rps28 Hsap\RPS28 viable "wing,macrochaeta,ectopic" FBgn0085461 CG34432 - http://flybase.org/reports/FBgn0085461 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34432, CG15541" - CG34432 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065598 l(2)SH0880 lethal (2) SH0880 http://flybase.org/reports/FBgn0065598 gene - - - "l(2)SH0880, l(2)SH2 0880" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260099 2L3443 - http://flybase.org/reports/FBgn0260099 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L3443 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0010425 epsilonTry epsilonTrypsin http://flybase.org/reports/FBgn0010425 FBgn0040762 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP88, Try, DmEpsilonTry, epsilon, epsilonTry, CG18681" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG18681 11-Aug-17 DroID_v2017_08 "Drer\prss60.3, Drer\LOC562139, Drer\si:dkeyp-93a5.2, Drer\zgc:112160, Drer\prss60.2, Drer\zgc:163079, Drer\prss60.1, Drer\zgc:112038, Drer\tmprss4b, Drer\zgc:55888, Drer\zgc:92590, Drer\zgc:153968, Drer\ctrl, Drer\try, Drer\zgc:123295" - "Cele\svh-1, Cele\try-1" - "Mmus\2210010C04Rik, Mmus\Try4, Mmus\Prss53, Mmus\Try10, Mmus\Prss55, Mmus\Gm5771, Mmus\Prss36, Mmus\Elane, Mmus\Prss3, Mmus\Prss34, Mmus\Prss1, Mmus\Gm10334, Mmus\Prss2" "Hsap\PRSS36, Hsap\PRSS53, Hsap\ELANE, Hsap\PRSS1, Hsap\PRSS3" viable FBgn0026575 hang hangover http://flybase.org/reports/FBgn0026575 "FBgn0030750, FBgn0030751, FBgn0052575, FBgn0062484" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003604 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | non-traceable author statement behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "BcDNA:LD22118, CG4416, CG4411, LD22118, BcDNA:GM07804, CG32575, hang, HANG" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR003604:Matrin/U1-C-like, C2H2-type zinc finger" CG32575 11-Aug-17 DroID_v2017_08 "Drer\gtf3aa, Drer\LOC568955" Scer\PZF1 "Cele\pqm-1, Cele\F21A9.2, Cele\F19C6.3, Cele\F10B5.3" - "Mmus\Gtf3a, Mmus\Thbs3" "Hsap\THBS3, Hsap\GTF3A" "viable,chemical sensitive,short lived,partially lethal - majority die,visible,lethal,female sterile,female semi-sterile" "wing,trichogen cell" FBgn0037022 CG11396 - http://flybase.org/reports/FBgn0037022 protein_coding_gene endopeptidase activity ; GO:0004175 | inferred from biological aspect of ancestor with PANTHER:PTN000491515 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11396 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1" CG11396 11-Aug-17 DroID_v2017_08 Drer\trappc12 Scer\TMN3 Cele\trpp-12 Xtro\trappc12 Mmus\Trappc12 Hsap\TRAPPC12 "viable,fertile,visible" trichogen cell FBgn0069143 mcl(3)Z4617 mcl(3)Z4617 http://flybase.org/reports/FBgn0069143 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z4617 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0065289 l(2)SH2016 lethal (2) SH2016 http://flybase.org/reports/FBgn0065289 gene - - - "l(2)SH2016, l(2)SH2 2016" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011595 FTasealpha Farnesyltransferase alpha subunit http://flybase.org/reports/FBgn0011595 - gene - - - FTasealpha - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036415 CG7768 - http://flybase.org/reports/FBgn0036415 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130" - CG7768 "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG7768 11-Aug-17 DroID_v2017_08 "Drer\ppil6, Drer\ppig, Drer\LOC103911964, Drer\ppiab, Drer\si:ch1073-55a19.2, Drer\ppie, Drer\ppib, Drer\ppifb, Drer\ppih, Drer\ppiaa, Drer\ppifa, Drer\LOC100333141, Drer\ppid, Drer\nktr" "Scer\CPR3, Scer\CPR6, Scer\CPR1, Scer\CPR4" "Cele\cyn-6, Cele\cyn-5, Cele\cyn-1, Cele\cyn-2, Cele\cyn-7, Cele\T22F3.12, Cele\cyn-9, Cele\Y17G9B.4, Cele\cyn-8, Cele\cyn-3, Cele\cyn-11" "Xtro\nktr, Xtro\ranbp2, Xtro\ppia, Xtro\ppib, Xtro\ppil6, Xtro\ppic, Xtro\ppif, Xtro\ppih, Xtro\ppie, Xtro\ppid" "Mmus\Ppig, Mmus\Ppib, Mmus\Ppil6, Mmus\Ppia, Mmus\Nktr, Mmus\Ppic, Mmus\Ppie, Mmus\Ppif, Mmus\Ppid, Mmus\Ranbp2, Mmus\Ppih" "Hsap\RANBP2, Hsap\RGPD1, Hsap\PPIF, Hsap\PPIE, Hsap\NKTR, Hsap\RGPD8, Hsap\RGPD2, Hsap\PPIAL4E, Hsap\PPIAL4G, Hsap\PPIA, Hsap\PPIAL4D, Hsap\PPIL6, Hsap\RGPD5, Hsap\LOC105371242, Hsap\PPIG, Hsap\PPIAL4A, Hsap\RGPD6, Hsap\PPIH, Hsap\RGPD3, Hsap\RGPD4, Hsap\PPIC, Hsap\PPIAL4C, Hsap\PPID, Hsap\PPIB" viable FBgn0002838 ms(3)K81 male sterile (3) K81 http://flybase.org/reports/FBgn0002838 FBgn0039460 protein_coding_gene - telomere capping ; GO:0016233 | inferred from mutant phenotype "nucleus ; GO:0005634 | inferred from direct assay chromosome, telomeric region ; GO:0000781 | inferred from direct assay condensed nuclear chromosome ; GO:0000794 | inferred from direct assay" "K81, ph, ms(3)k81, ms(3)97Dg, CG14251, ms(3)K81, k81, ms(3)[K81]" - CG14251 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,paternal effect,lethal,viable,male sterile" chromosome | paternal effect FBgn0039511 CG3330 - http://flybase.org/reports/FBgn0039511 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "anon-WO0140519.147, CG3330" - CG3330 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033454 CG1671 - http://flybase.org/reports/FBgn0033454 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000457905 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000457905 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000457905 Pwp2p-containing subcomplex of 90S preribosome ; GO:0034388 | inferred from biological aspect of ancestor with PANTHER:PTN000457905 CG1671 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013934:Small-subunit processome, Utp13, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG1671 11-Aug-17 DroID_v2017_08 "Drer\wdr5, Drer\tbl3" "Scer\UTP13, Scer\SWD3" "Cele\wdr-5.1, Cele\Y53C12B.1" "Xtro\wdr5, Xtro\tbl3" "Mmus\Tbl3, Mmus\Wdr5b, Mmus\Wdr5" "Hsap\TBL3, Hsap\WDR5B, Hsap\WDR5" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0035336 CG9004 - http://flybase.org/reports/FBgn0035336 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000427685 neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal small subunit biogenesis ; GO:0042274 | inferred from biological aspect of ancestor with PANTHER:PTN000427762 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q5C9Z4 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000427762 CG9004 "IPR003890:MIF4G-like, type 3, IPR003891:Initiation factor eIF-4 gamma, MA3, IPR016024:Armadillo-type fold" CG9004 11-Aug-17 DroID_v2017_08 Drer\nom1 Scer\SGD1 Cele\Y52B11A.10 Xtro\nom1 Mmus\Nom1 Hsap\NOM1 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0259960 CG42470 - http://flybase.org/reports/FBgn0259960 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42470 - CG42470 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033918 CG8531 - http://flybase.org/reports/FBgn0033918 protein_coding_gene ATPase activator activity ; GO:0001671 | inferred from sequence or structural similarity with SGD:S000004080 protein import into mitochondrial matrix ; GO:0030150 | inferred from sequence or structural similarity with SGD:S000004080 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000004080 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000004080 CG8531 "IPR001623:DnaJ domain, IPR024586:DnaJ-like protein C11, C-terminal" CG8531 11-Aug-17 DroID_v2017_08 Drer\dnajc11 "Scer\SCJ1, Scer\JJJ1, Scer\APJ1, Scer\ERJ5, Scer\XDJ1" Cele\dnj-9 Xtro\dnajc11 Mmus\Dnajc11 Hsap\DNAJC11 "viable,fertile" "wing,posterior compartment" FBgn0262432 mir-8 mir-8 stem loop http://flybase.org/reports/FBgn0262432 miRNA_gene - positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from direct assay Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype female pigmentation ; GO:0048095 | inferred from mutant phenotype positive regulation of eclosion ; GO:0045805 | inferred from mutant phenotype negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype glial cell growth ; GO:0042065 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with spi positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype subsynaptic reticulum organization ; GO:1990255 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype - "miR-8, dme-mir-8, mir-8, 8, MIR-8, CR42988, CR33018, 8 mir, dme-miR-8, MiR-8, miR8, CR33562, mir-8*, mir-8S, mir8S, dme-miR-8-3p" - CR42988 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0060491 l(3)S110006b lethal (3) S110006b http://flybase.org/reports/FBgn0060491 gene - - - "1100/06, l(3)S110006b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051102 CG31102 - http://flybase.org/reports/FBgn0051102 protein_coding_gene - - - "CG10634, CG31102" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31102 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.8, Cele\C29F7.2, Cele\F59B1.10, Cele\dhs-27, Cele\C29F7.1, Cele\H06H21.8, Cele\nhr-246" - - - viable DRSC14260 I -0.657362049 7.161830223 0.170485258 0.442561105 -0.065256733 0.448166557 FBgn0063415 l(3)3450-H lethal (3) 3450-H http://flybase.org/reports/FBgn0063415 gene - - - l(3)3450-H - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053437 5SrRNA:CR33437 5SrRNA:CR33437 http://flybase.org/reports/FBgn0053437 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33437, 5SrRNA:CR33437" - CR33437 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264888 CR44079 - http://flybase.org/reports/FBgn0264888 pseudogene_attribute - - - CR44079 - CR44079 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040321 GNBP3 Gram-negative bacteria binding protein 3 http://flybase.org/reports/FBgn0040321 protein_coding_gene signaling pattern recognition receptor activity ; GO:0008329 | inferred from sequence or structural similarity with GNBP1 beta-glucanase activity ; GO:0052736 | NOT inferred from key residues lipopolysaccharide binding ; GO:0001530 | inferred from direct assay (1->3)-beta-D-glucan binding ; GO:0001872 | inferred from direct assay carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000757 regulation of innate immune response ; GO:0045088 | inferred from sequence or structural similarity with UniProtKB:Q9NHB0 detection of molecule of fungal origin ; GO:0032491 | inferred from direct assay innate immune response-activating signal transduction ; GO:0002758 | inferred from sequence or structural similarity with GNBP1 response to fungus ; GO:0009620 | non-traceable author statement cell surface ; GO:0009986 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:Q9NHB0 "Hades, GNBP, DGNBP-3, CG5008, GNBP3, gnbp3, GNBP-3, Gnbp3" "IPR000757:Glycoside hydrolase family 16, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR031756:Beta-1,3-glucan-binding protein, N-terminal" CG5008 11-Aug-17 DroID_v2017_08 - "Scer\CRR1, Scer\CRH1, Scer\UTR2" - - - - "immune response defective,viable" FBgn0001340 l(1)1Bh lethal (1) 1Bh http://flybase.org/reports/FBgn0001340 - gene - - - "l(1)PB, l(1)1Bh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,lethal - all die before end of pupal stage,recessive,some die during pupal stage,partially lethal - majority die,visible" wing FBgn0034654 eIF3k eukaryotic translation initiation factor 3 subunit k http://flybase.org/reports/FBgn0034654 protein_coding_gene ribosome binding ; GO:0043022 | inferred from electronic annotation with InterPro:IPR016020 translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000314720 translation initiation factor activity ; GO:0003743 | contributes_to inferred from sequence or structural similarity with HGNC:24656 regulation of translational initiation ; GO:0006446 | inferred from electronic annotation with InterPro:IPR016020 translational initiation ; GO:0006413 | inferred from sequence or structural similarity with HGNC:24656 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:24656 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000314720 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with HGNC:24656 "CG10306, eIF3k" "IPR009374:Eukaryotic translation initiation factor 3 subunit K, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016020:Translation initiation factor 3, subunit 12, N-terminal, eukaryotic, IPR016024:Armadillo-type fold, IPR033464:CSN8/PSMD8/EIF3K" CG10306 11-Aug-17 DroID_v2017_08 Drer\eif3k - Cele\eif-3.K Xtro\eif3k Mmus\Eif3k Hsap\EIF3K FBgn0037110 ORMDL ORMDL http://flybase.org/reports/FBgn0037110 protein_coding_gene - negative regulation of ceramide biosynthetic process ; GO:1900060 | inferred from biological aspect of ancestor with PANTHER:PTN000292374 cellular sphingolipid homeostasis ; GO:0090156 | inferred from biological aspect of ancestor with PANTHER:PTN000292374 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007203 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with UniProtKB:Q9P0S3 SPOTS complex ; GO:0035339 | inferred from biological aspect of ancestor with PANTHER:PTN000292374 cytosol ; GO:0005829 | inferred from direct assay "CG14577, ORMDL" IPR007203:ORMDL family CG14577 11-Aug-17 DroID_v2017_08 "Drer\ormdl1, Drer\ormdl2, Drer\ormdl3" "Scer\ORM1, Scer\ORM2" "Cele\T10C6.10, Cele\F29G9.7" "Xtro\ormdl1, Xtro\ormdl2" "Mmus\Ormdl2, Mmus\Ormdl1, Mmus\Ormdl3" "Hsap\ORMDL3, Hsap\ORMDL1, Hsap\ORMDL2" "viable,fertile" FBgn0001646 l(1)dn26 lethal (1) discs normal 26 http://flybase.org/reports/FBgn0001646 - gene - - - "l(1)d.norm.-26, l(1)dn26" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005299 mei-I3 meiotic I3 http://flybase.org/reports/FBgn0005299 - gene - - - mei-I3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive" "meiosis I,meiosis II" FBgn0003902 Two-b Two bristles http://flybase.org/reports/FBgn0003902 FBgn0004615 gene - - - Two-b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable,good" "postvertical bristle,dorsocentral bristle" FBgn0035542 DOR Diabetes and obesity regulated http://flybase.org/reports/FBgn0035542 protein_coding_gene steroid hormone receptor binding ; GO:0035258 | inferred from physical interaction with EcR ligand-dependent nuclear receptor transcription coactivator activity ; GO:0030374 | inferred from direct assay regulation of autophagy ; GO:0010506 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN001270888 ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001270888 autophagosome ; GO:0005776 | inferred from biological aspect of ancestor with PANTHER:PTN001270888 nucleus ; GO:0005634 | inferred by curator from GO:0030374 "CG11347, DOR, dDOR" IPR029431:Tumour protein p53-inducible nuclear protein CG11347 11-Aug-17 DroID_v2017_08 "Drer\tp53inp2, Drer\tp53inp1" - - "Xtro\tp53inp1, Xtro\tp53inp2" "Mmus\Trp53inp1, Mmus\Trp53inp2" "Hsap\TP53INP2, Hsap\TP53INP1" "lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage,viable" "anterior pupal spiracle,salivary gland,autophagic vacuole" FBgn0016010 l(3)63Fd lethal (3) 63Fd http://flybase.org/reports/FBgn0016010 - gene - - - "l(3)SH6, l(3)63Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010121 l(1)8Ab lethal (1) 8Ab http://flybase.org/reports/FBgn0010121 - gene - - - "HF383, l(1)8Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0051162 tRNA:Ser-GCT-2-4 transfer RNA:Serine-GCT 2-4 http://flybase.org/reports/FBgn0051162 tRNA_gene AGC codon-amino acid adaptor activity ; GO:0033446 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033446 cytosol ; GO:0005829 | inferred by curator from GO:0033446 "tRNA[Ser][[2b]], AE002708.trna39-SerGCT, tRNA:S:GCT:AE002708-d, tRNA:ser, tRNA:S, tRNA:ser2b:94A, tRNA:ser2b, tRNA:S2b, tRNA:S2b:94A, CR31162, tRNA[[Ser]], chr3R.trna45-SerGCT, tRNA-Ser-GCT-2-4, tRNA:Ser-GCT-2-4, tRNA:CR31162, AGC" - CR31162 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027135 l(3)89ABa lethal (3) 89ABa http://flybase.org/reports/FBgn0027135 - gene - - - l(3)89ABa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046326 ms(2)38ABa ms(2)38ABa http://flybase.org/reports/FBgn0046326 gene - - - "ms in 38A/B, ms(2)38ABa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031170 CG1718 - http://flybase.org/reports/FBgn0031170 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 CG1718 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR026082:ABC transporter A, ABCA" CG1718 11-Aug-17 DroID_v2017_08 "Drer\abch1, Drer\abca3b, Drer\abca12, Drer\abca1a, Drer\abca1b, Drer\abca5, Drer\abca2" "Scer\PDR18, Scer\PDR15, Scer\CAF16, Scer\PDR5, Scer\YOL075C, Scer\PDR10, Scer\SNQ2, Scer\PDR11, Scer\AUS1, Scer\PDR12" "Cele\abt-2, Cele\abt-4, Cele\ced-7, Cele\abt-5" "Xtro\abca2, Xtro\abca1, Xtro\abca3, Xtro\abca9, Xtro\abca8, Xtro\abca10, Xtro\abca4" "Mmus\Abca3, Mmus\Abca17, Mmus\Abca15, Mmus\Abca13, Mmus\Abca6, Mmus\Abca4, Mmus\Abca5, Mmus\Abca8b, Mmus\Abca9, Mmus\Abca1, Mmus\Abca7, Mmus\Abca8a, Mmus\Abca12, Mmus\Abca2, Mmus\Abca16, Mmus\Abca14" "Hsap\ABCA6, Hsap\ABCA10, Hsap\ABCA3, Hsap\ABCA7, Hsap\ABCA1, Hsap\ABCA2, Hsap\ABCA8, Hsap\ABCA5, Hsap\ABCA9, Hsap\ABCA4, Hsap\ABCA13, Hsap\ABCA12" viable DRSC20546 K 0.229437717 0.315420842 0.25940021 0.91173629 -0.208019204 -1.509490163 FBgn0013724 Raf::tor phl::tor http://flybase.org/reports/FBgn0013724 - engineered_fusion_gene - - - "raf, sev-raf, phl::tor, Raf::tor" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "ommatidium,photoreceptor cell R7,supernumerary,eye,ectopic,cone cell,photoreceptor cell,abdomen,eye disc,somatic clone" FBgn0039489 CG5880 - http://flybase.org/reports/FBgn0039489 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 Golgi apparatus ; GO:0005794 | inferred from direct assay CG5880 "IPR001594:Palmitoyltransferase, DHHC domain" CG5880 11-Aug-17 DroID_v2017_08 "Drer\zdhhc16b, Drer\zdhhc16a" "Scer\PFA3, Scer\SWF1" "Cele\dhhc-9, Cele\dhhc-12" Xtro\zdhhc16 Mmus\Zdhhc16 Hsap\ZDHHC16 "lethal,partially lethal - majority die,some die during pupal stage" FBgn0266357 CR45005 - http://flybase.org/reports/FBgn0266357 non_protein_coding_gene - - - CR45005 - CR45005 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260084 2L3179 - http://flybase.org/reports/FBgn0260084 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3179 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone,dorsal air sac primordium" FBgn0264987 CR44138 - http://flybase.org/reports/FBgn0264987 non_protein_coding_gene - - - CR44138 - CR44138 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024653 l(2)k08307 lethal (2) k08307 http://flybase.org/reports/FBgn0024653 - gene - - - "83/7, l(2)k08307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032089 Rcd-1r Rcd-1 related http://flybase.org/reports/FBgn0032089 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatogenesis ; GO:0007283 | inferred from expression pattern negative regulation of translation ; GO:0017148 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 reproductive process ; GO:0022414 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 nucleus ; GO:0005634 | inferred from direct assay "CG9573, Drcd-1r, Rcd-1r, Zeus" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG9573 11-Aug-17 DroID_v2017_08 Drer\rqcd1 Scer\CAF40 Cele\ntl-9 Xtro\rqcd1 Mmus\Cnot9 Hsap\CNOT9 "male semi-sterile,female fertile,male semi-fertile" testis FBgn0021995 Rs1 Rs1 http://flybase.org/reports/FBgn0021995 FBgn0028477 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000003931 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ribosome biogenesis ; GO:0042254 | non-traceable author statement positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype - "153844_at, DmRH21, cg2173, l(2)k09514, Drs1, CG2173, BcDNA:GM05306, Rs1" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2173 11-Aug-17 DroID_v2017_08 Drer\ddx27 Scer\DRS1 Cele\ddx-27 Xtro\ddx27 Mmus\Ddx27 Hsap\DDX27 "lethal,recessive,viable,visible" mesothoracic tergum DRSC05945 E -1.395678537 0.720694061 1.543172694 -0.124592027 -0.063330169 -0.169392667 FBgn0024678 l(1)LefEM3 lethal (1) LefEM3 http://flybase.org/reports/FBgn0024678 - gene - - - "EM3, l(1)LefEM3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265084 CG44195 - http://flybase.org/reports/FBgn0265084 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44195 - CG44195 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267990 CR46257 - http://flybase.org/reports/FBgn0267990 non_protein_coding_gene - - - CR46257 - CR46257 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267722 CR46055 - http://flybase.org/reports/FBgn0267722 non_protein_coding_gene - - - CR46055 - CR46055 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259919 Csp::nSyb - http://flybase.org/reports/FBgn0259919 engineered_fusion_gene - - - "Csp::n-syb, Csp::n-Syb, Csp::nSyb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052699 LPCAT Lysophosphatidylcholine acyltransferase http://flybase.org/reports/FBgn0052699 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 lysophospholipid acyltransferase activity ; GO:0071617 | inferred from mutant phenotype 1-acylglycerophosphocholine O-acyltransferase activity ; GO:0047184 | inferred from sequence or structural similarity with UniProtKB:Q3TFD2 phospholipid biosynthetic process ; GO:0008654 | inferred from sequence or structural similarity with UniProtKB:Q3TFD2 lipid modification ; GO:0030258 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with UniProtKB:Q3TFD2 lipid particle ; GO:0005811 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q3TFD2 "CG2996, tok-like, CT7882, CG15318, CG18535, LPCAT, CG32699, LPCAT1/2" "IPR002123:Phospholipid/glycerol acyltransferase, IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG32699 11-Aug-17 DroID_v2017_08 "Drer\LOC101884921, Drer\lpcat1, Drer\LOC100536112, Drer\lpcat2, Drer\lpcat4" - Cele\acl-8 "Xtro\lpcat4, Xtro\lpcat2, Xtro\lpcat1" "Mmus\Lpcat4, Mmus\Lpcat2, Mmus\Lpcat2b, Mmus\Lpcat1" "Hsap\LPCAT1, Hsap\LPCAT4, Hsap\LPCAT2" "viable,fertile,visible" mesothoracic tergum FBgn0030670 Pis Phosphatidylinositol synthase http://flybase.org/reports/FBgn0030670 protein_coding_gene CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity ; GO:0003881 | inferred from direct assay basement membrane organization ; GO:0071711 | inferred from mutant phenotype phosphatidylinositol biosynthetic process ; GO:0006661 | inferred from biological aspect of ancestor with PANTHER:PTN000394714 phototransduction ; GO:0007602 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000462 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000394714 "anon-WO02059370.38, Pis, dpis, dPIS, CG9245, dPis" "IPR000462:CDP-alcohol phosphatidyltransferase, IPR014387:CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote" CG9245 11-Aug-17 DroID_v2017_08 Drer\cdipt Scer\PIS1 Cele\pisy-1 Xtro\cdipt Mmus\Cdipt Hsap\CDIPT "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,heat sensitive,neurophysiology defective" "eye,somatic clone,eye photoreceptor cell,rhabdomere,rhabdomere, with Pishs.THsapMYC,rhabdomere, with Pis1" FBgn0002704 Me Moire http://flybase.org/reports/FBgn0002704 - gene - - - "Mo, Me" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive,eye color defective" "eye,pigment cell,macrochaeta" FBgn0053433 5SrRNA:CR33433 5SrRNA:CR33433 http://flybase.org/reports/FBgn0053433 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33433, 5SrRNA:CR33433" - CR33433 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031430 CG3528 - http://flybase.org/reports/FBgn0031430 protein_coding_gene - - - CG3528 IPR027887:Protein of unknown function DUF4464 CG3528 11-Aug-17 DroID_v2017_08 Drer\si:ch211-57h10.1 - - - Mmus\1700007G11Rik Hsap\C4orf22 FBgn0263615 CR43624 - http://flybase.org/reports/FBgn0263615 non_protein_coding_gene - - - CR43624 - CR43624 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0284247 ds dachsous http://flybase.org/reports/FBgn0284247 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from direct assay receptor activity ; GO:0004872 | inferred from sequence or structural similarity cadherin binding ; GO:0045296 | inferred from physical interaction with ft cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity signal transducer activity ; GO:0004871 | non-traceable author statement "homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity microtubule cytoskeleton organization involved in establishment of planar polarity ; GO:0090176 | inferred from mutant phenotype wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype establishment of tissue polarity ; GO:0007164 | non-traceable author statement cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from direct assay single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype equator specification ; GO:0045317 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from physical interaction with ft establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype eye morphogenesis ; GO:0048592 | inferred from mutant phenotype calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from direct assay homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from sequence or structural similarity imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | traceable author statement establishment of planar polarity ; GO:0001736 | traceable author statement establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype inferred from genetic interaction with ft regulation of establishment of planar polarity ; GO:0090175 | inferred from genetic interaction with dgo" integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | traceable author statement "l(2)01855, Ds, ds, CT39575, l(2)05142, cad2, CG17941, EP-822, dachs" "IPR027397:Catenin binding domain, IPR002126:Cadherin, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site" CG17941 11-Aug-17 DroID_v2017_08 "Drer\fat1a, Drer\fat1b, Drer\si:ch211-186j3.6, Drer\si:dkey-22o22.2, Drer\dchs2, Drer\cdh23, Drer\dchs1b, Drer\fat3a, Drer\dchs1a, Drer\fat2" - "Cele\cdh-1, Cele\fmi-1, Cele\cdh-4, Cele\hmr-1, Cele\cdh-3" "Xtro\fat1, Xtro\dchs2, Xtro\fat4" "Mmus\Fat1, Mmus\Fat4, Mmus\Cdh23, Mmus\Fat3, Mmus\Dchs1, Mmus\Fat2" "Hsap\FAT4, Hsap\DCHS1, Hsap\DCHS2, Hsap\FAT2, Hsap\DLK2, Hsap\FAT1, Hsap\FAT3, Hsap\CDH23" "lethal,recessive,partially lethal - majority die" FBgn0051463 CG31463 - http://flybase.org/reports/FBgn0051463 protein_coding_gene - - - "CG11673, CG31463" - CG31463 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0024625 l(3)63Db lethal (3) 63Db http://flybase.org/reports/FBgn0024625 - gene - - - "c.g.15, l(3)63Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065820 l(2)SH0369 lethal (2) SH0369 http://flybase.org/reports/FBgn0065820 gene - - - "l(2)SH0369, l(2)SH2 0369" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266675 CR45165 - http://flybase.org/reports/FBgn0266675 non_protein_coding_gene - - - CR45165 - CR45165 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001407 l(1)3Bb lethal (1) 3Bb http://flybase.org/reports/FBgn0001407 - gene - - - "zw-6, l(1)zw6, zw6, ZW-6, l(1)3Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,rescuable maternal effect,partially lethal - majority die,female sterile" tergite FBgn0005379 fs(2)OW207 female sterile (2) OW207 http://flybase.org/reports/FBgn0005379 - gene - - - fs(2)OW207 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085797 CR41540 - http://flybase.org/reports/FBgn0085797 rRNA_gene - - - CR41540 - CR41540 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267935 CR46215 - http://flybase.org/reports/FBgn0267935 non_protein_coding_gene - - - "CR46215, lincRNA.604" - CR46215 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003699 thl thick legs http://flybase.org/reports/FBgn0003699 - gene - - - thl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male fertile,viable,male,reduced,recessive,eye color defective,body color defective" "wing,leg,metathoracic leg,tibia,tarsal segment,pigment cell" FBgn0039427 CG5447 - http://flybase.org/reports/FBgn0039427 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000327115 peptidyl-L-cysteine S-palmitoylation ; GO:0018230 | inferred from biological aspect of ancestor with PANTHER:PTN000327115 protein targeting to membrane ; GO:0006612 | inferred from biological aspect of ancestor with PANTHER:PTN000327115 protein localization to plasma membrane ; GO:0072659 | inferred from biological aspect of ancestor with PANTHER:PTN000327115 Golgi to plasma membrane protein transport ; GO:0043001 | inferred from sequence or structural similarity with HGNC:24876 intrinsic component of Golgi membrane ; GO:0031228 | inferred from sequence or structural similarity with HGNC:24876 palmitoyltransferase complex ; GO:0002178 | inferred from biological aspect of ancestor with PANTHER:PTN000327115 CG5447 IPR019383:Golgin subfamily A member 7/ERF4 CG5447 11-Aug-17 DroID_v2017_08 "Drer\golga7ba, Drer\golga7, Drer\golga7bb" Scer\SHR5 Cele\Y57G11C.33 "Xtro\golga7, Xtro\golga7b" "Mmus\Golga7b, Mmus\Golga7" "Hsap\GOLGA7, Hsap\GOLGA7B" "viable,fertile" FBgn0064156 mod(Fmr1) modifier of Fmr1 http://flybase.org/reports/FBgn0064156 gene - - - mod(Fmr1) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011450 l(3)neo6 lethal (3) neo6 http://flybase.org/reports/FBgn0011450 - gene - - - l(3)neo6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003541 St(SD) Stabilizer of Segregation Distorter http://flybase.org/reports/FBgn0003541 - gene - - - "St(SD), St-SD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260990 yata yata http://flybase.org/reports/FBgn0260990 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein phosphorylation ; GO:0006468 | NOT inferred from key residues - "CG1973, yata, Yata" "IPR000719:Protein kinase domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR011009:Protein kinase-like domain" CG1973 11-Aug-17 DroID_v2017_08 "Drer\scyl1, Drer\scyl3" Scer\CEX1 Cele\W07G4.3 "Xtro\scyl1, Xtro\scyl3" "Mmus\Scyl1, Mmus\Scyl3" "Hsap\SCYL1, Hsap\SCYL3" FBgn0260095 2L3244 - http://flybase.org/reports/FBgn0260095 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L3244 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0001462 l(1)7Ec lethal (1) 7Ec http://flybase.org/reports/FBgn0001462 - gene - - - l(1)7Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038002 CG12256 - http://flybase.org/reports/FBgn0038002 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP133, CG12256" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG12256 11-Aug-17 DroID_v2017_08 Drer\st14b - - - Mmus\Ctrc Hsap\CTRC "partially lethal - majority die,some die during pupal stage,viable" FBgn0264372 CR43824 - http://flybase.org/reports/FBgn0264372 non_protein_coding_gene - - - CR43824 - CR43824 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086257 caps::trn - http://flybase.org/reports/FBgn0086257 engineered_fusion_gene - - - caps::trn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266027 lncRNA:TS15 long noncoding RNA: testis-specific 15 http://flybase.org/reports/FBgn0266027 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "lncRNA:TS15, CR44792" - CR44792 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264482 CR43890 - http://flybase.org/reports/FBgn0264482 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43890, CR43890" - CR43890 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016804 l(1)K6 lethal (1) K6 http://flybase.org/reports/FBgn0016804 - gene - - - "l(1)K6, K6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053978 CG33978 - http://flybase.org/reports/FBgn0053978 protein_coding_gene "extracellular matrix structural constituent ; GO:0005201 | inferred from electronic annotation with InterPro:IPR011398 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 molecular_function ; GO:0003674 | no biological data available" biological_process ; GO:0008150 | no biological data available proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR011398 cellular_component ; GO:0005575 | no biological data available "CG33978, FBgn0053978" "IPR011398:Fibrillin, IPR000742:EGF-like domain, IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR031866:Domain of unknown function DUF4758" CG33978 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263412 CR43458 - http://flybase.org/reports/FBgn0263412 non_protein_coding_gene - - - "CR43458, lincRNA.913" - CR43458 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084894 Su(dpp)YE31 Su(dpp)YE31 http://flybase.org/reports/FBgn0084894 gene - - - Su(dpp)YE31 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic dorsal epidermis,amnioserosa" FBgn0003187 qua quail http://flybase.org/reports/FBgn0003187 "FBgn0000942, FBgn0044556" protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity with Gel inferred from sequence or structural similarity with HGNC:12690 inferred from direct assay inferred from mutant phenotype actin binding ; GO:0003779 | inferred from sequence or structural similarity calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with HGNC:12690 cytoskeleton organization ; GO:0007010 | inferred from electronic annotation with InterPro:IPR003128 actin filament organization ; GO:0007015 | traceable author statement imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype actin filament ; GO:0005884 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG6433, anon-WO0140519.71, fs(2)A12, qua, Qua" "IPR003128:Villin headpiece, IPR007122:Villin/Gelsolin, IPR007123:Gelsolin-like domain, IPR029006:ADF-H/Gelsolin-like domain" CG6433 11-Aug-17 DroID_v2017_08 "Drer\gsnb, Drer\scinla, Drer\capga, Drer\gsna, Drer\avil, Drer\scinlb, Drer\capgb, Drer\scin, Drer\vil1, Drer\vill" - Cele\gsnl-1 "Xtro\vill, Xtro\capg, Xtro\scin, Xtro\vil1, Xtro\avil, Xtro\gsn" "Mmus\Gsn, Mmus\Scin, Mmus\Vill, Mmus\Avil, Mmus\Capg, Mmus\Vil1" "Hsap\AVIL, Hsap\SCIN, Hsap\CAPG, Hsap\GSN, Hsap\VIL1, Hsap\VILL" " adult stage | female , adult stage && oogenesis stage , embryonic stage | 0-4 hr , pupal stage , spermatogenesis && adult stage " " ovary

, nurse cell

, testis

, oocyte

" adult stage && oogenesis stage " nurse cell

, oocyte

, ring canal

" "female sterile,recessive,viable,fertile,mitotic cell cycle defective,wild-type,heat sensitive" "nurse cell,egg,egg chamber,nurse follicle cell,oocyte,nurse cell ring canal,actin filament & egg chamber,dorsal appendage,female reproductive system,spindle,nurse cell & actin filament,ovary,wing hair" FBgn0000170 bef beta lobes fused http://flybase.org/reports/FBgn0000170 - gene - - - "bef[BG17b], bef" - - 11-Aug-17 DroID_v2017_08 - - - - - - mushroom body beta-lobe FBgn0036110 Cpr67Fb Cuticular protein 67Fb http://flybase.org/reports/FBgn0036110 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr67Fb, CG18348, DmelCpr67Fb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG18348 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0001549 l(1)16Fc lethal (1) 16Fc http://flybase.org/reports/FBgn0001549 - gene - - - "ME-III, l(1)16Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,uncoordinated,somatic clone,neurophysiology defective,recessive,behavior defective,lethal - all die before end of larval stage,dominant,non-rescuable maternal effect,some die during larval stage" "wing,leg" FBgn0052568 CG32568 - http://flybase.org/reports/FBgn0052568 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from electronic annotation with InterPro:IPR002554 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002554 protein phosphatase type 2A complex ; GO:0000159 | inferred from electronic annotation with InterPro:IPR002554 "CG4724, CG32568" "IPR002554:Protein phosphatase 2A, regulatory B subunit, B56, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG32568 11-Aug-17 DroID_v2017_08 "Drer\ppp2r5ca, Drer\ppp2r5a, Drer\ppp2r5ea, Drer\ppp2r5eb, Drer\ppp2r5b, Drer\ppp2r5d" Scer\RTS1 "Cele\pptr-2, Cele\pptr-1" "Xtro\ppp2r5c, Xtro\ppp2r5b, Xtro\ppp2r5a, Xtro\ppp2r5e" "Mmus\Ppp2r5e, Mmus\Ppp2r5d, Mmus\Ppp2r5a, Mmus\Ppp2r5c, Mmus\Ppp2r5b" "Hsap\PPP2R5E, Hsap\PPP2R5D, Hsap\PPP2R5C, Hsap\PPP2R5B, Hsap\PPP2R5A" viable FBgn0016120 ATPsynD "ATP synthase, subunit D" http://flybase.org/reports/FBgn0016120 - protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000294648 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000001499" determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000001499 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000294648 ATP metabolic process ; GO:0046034 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype negative regulation of ERK1 and ERK2 cascade ; GO:0070373 | inferred from mutant phenotype proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:O75947 regulation of mitochondrial membrane potential ; GO:0051881 | inferred from mutant phenotype "mitochondrial proton-transporting ATP synthase, stator stalk ; GO:0000274 | inferred from biological aspect of ancestor with PANTHER:PTN000294648 lipid particle ; GO:0005811 | inferred from direct assay mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with UniProtKB:O75947 mitochondrion ; GO:0005739 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay" "CG6030, ATPsyn-delta, ATPsyn-D, ATPsyn-d, ATPQ, ATPsynD, ATP syn-d" "IPR008689:ATP synthase, F0 complex, subunit D, mitochondrial" CG6030 11-Aug-17 DroID_v2017_08 Drer\atp5h Scer\ATP7 Cele\atp-5 Xtro\atp5h Mmus\Atp5h Hsap\ATP5H "lethal,visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0005224 l(3)ET26 lethal Elaine Tasaka 26 http://flybase.org/reports/FBgn0005224 - gene - - - l(3)ET26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cold sensitive" FBgn0037583 CG9684 - http://flybase.org/reports/FBgn0037583 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG9684 "IPR002999:Tudor domain, IPR002893:Zinc finger, MYND-type" CG9684 11-Aug-17 DroID_v2017_08 "Drer\smyd1b, Drer\smyd2b, Drer\smyd3, Drer\smyd1a, Drer\smyd2a" - "Cele\set-30, Cele\set-10, Cele\set-18" Xtro\smyd1 "Mmus\Smyd3, Mmus\Smyd2, Mmus\Smyd1" "Hsap\SMYD3, Hsap\SMYD1, Hsap\SMYD2" "viable,fertile" FBgn0043061 Tl::Toll-7 Tl::Toll-7 http://flybase.org/reports/FBgn0043061 engineered_fusion_gene - - - Tl::Toll-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040531 CG11741 - http://flybase.org/reports/FBgn0040531 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11741 - CG11741 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001693 l(1)ESHS14 lethal (1) ESHS14 http://flybase.org/reports/FBgn0001693 - gene - - - "2/16B/1, l(1)ESHS14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005715 l(1)TK119 lethal (1) TK119 http://flybase.org/reports/FBgn0005715 - gene - - - "l119, l(1)TK119" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0010730 l(3)00836 lethal (3) 00836 http://flybase.org/reports/FBgn0010730 - gene - - - l(3)00836 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016755 Toki Toki http://flybase.org/reports/FBgn0016755 - gene - - - Toki - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,semidominant" FBgn0266282 jnj java no jive http://flybase.org/reports/FBgn0266282 protein_coding_gene SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000004375 damaged DNA binding ; GO:0003684 | inferred from sequence or structural similarity with SGD:S000004375 double-strand break repair via homologous recombination ; GO:0000724 | inferred from electronic annotation with InterPro:IPR027132 response to caffeine ; GO:0031000 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000004375 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000004375 germinal vesicle ; GO:0042585 | inferred from direct assay Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000004375 "CG5524, AAF56254, jnj, huc95E, Smc6, huc[95D-E], huc[95E], huc[95DE], Huc-95DE, SMC6, smc6" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027132:Structural maintenance of chromosomes protein 6, IPR003395:RecF/RecN/SMC, N-terminal" CG5524 11-Aug-17 DroID_v2017_08 "Drer\msrb3, Drer\si:dkey-119f1.1, Drer\smc6, Drer\msrb1b, Drer\msrb2" Scer\SMC6 "Cele\smc-5, Cele\smc-6, Cele\F44E2.6, Cele\C23H4.6" "Xtro\msrb2, Xtro\LOC100496941, Xtro\smc6, Xtro\smc6" "Mmus\Msrb2, Mmus\Msrb3, Mmus\Smc6, Mmus\Msrb1" "Hsap\MSRB2, Hsap\SMC6, Hsap\MSRB3" FBgn0034655 CG10307 - http://flybase.org/reports/FBgn0034655 protein_coding_gene - - - "CT28947, CG10307" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG10307 11-Aug-17 DroID_v2017_08 "Drer\lrrc47, Drer\si:dkey-1h4.4" - Cele\Y54E10A.6 Xtro\lrrc47 "Mmus\Lrrc2, Mmus\Lrrc39, Mmus\Lrrc10b, Mmus\Lrrd1" "Hsap\LRRC10, Hsap\LRRD1, Hsap\LRRC47, Hsap\LRRC39, Hsap\LRRC10B" viable DRSC04057 I 1.55075864 0.879384006 0.111249523 -0.498188965 0.764813819 -0.414527188 FBgn0267633 CR45971 - http://flybase.org/reports/FBgn0267633 non_protein_coding_gene - - - CR45971 - CR45971 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066323 val valiet http://flybase.org/reports/FBgn0066323 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available val - - 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,chemical sensitive,neurophysiology defective" FBgn0011054 l(1)Q7 lethal (1) Q7 http://flybase.org/reports/FBgn0011054 FBgn0010210 gene - - - l(1)Q7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031803 ppk14 pickpocket 14 http://flybase.org/reports/FBgn0031803 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK14, CG9501, ppk14" "IPR001873:Epithelial sodium channel, IPR020903:Epithelial sodium channel, conserved site" CG9501 11-Aug-17 DroID_v2017_08 "Drer\asic1b, Drer\asic4b, Drer\asic1c, Drer\asic4a, Drer\asic2, Drer\asic1a" - "Cele\delm-1, Cele\egas-1, Cele\egas-4, Cele\mec-4, Cele\unc-105, Cele\acd-4, Cele\egas-3, Cele\egas-2, Cele\del-8, Cele\unc-8, Cele\acd-5, Cele\mec-10, Cele\del-10, Cele\flr-1, Cele\delm-2, Cele\del-7, Cele\del-4, Cele\asic-1, Cele\del-1, Cele\degt-1, Cele\acd-1, Cele\asic-2, Cele\acd-2, Cele\deg-1" "Xtro\asic4, Xtro\scnn1d, Xtro\scnn1g, Xtro\scnn1b, Xtro\scnn1a, Xtro\asic5, Xtro\asic1" "Mmus\Asic2, Mmus\Scnn1b, Mmus\Asic3, Mmus\Asic4, Mmus\Scnn1g, Mmus\Asic1, Mmus\Asic5, Mmus\Scnn1a" "Hsap\ASIC4, Hsap\ASIC3, Hsap\ASIC5, Hsap\SCNN1D, Hsap\SCNN1B, Hsap\SCNN1A, Hsap\ASIC2, Hsap\SCNN1G, Hsap\ASIC1" viable FBgn0015342 anon-84Aa anon-84Aa http://flybase.org/reports/FBgn0015342 - gene - - - anon-84Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259104 dar5 dendritic arbor reduction 5 http://flybase.org/reports/FBgn0259104 gene - positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype - dar5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070003 BG01564 BG01564 http://flybase.org/reports/FBgn0070003 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01564 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,viable,smell perception defective" FBgn0065661 l(2)SH0713 lethal (2) SH0713 http://flybase.org/reports/FBgn0065661 gene - - - "l(2)SH0713, l(2)SH2 0713" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052091 CG32091 - http://flybase.org/reports/FBgn0052091 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CG7346, CG14136, CG32091" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG32091 11-Aug-17 DroID_v2017_08 "Drer\abcg4a, Drer\abcg4b, Drer\abcg1" "Scer\YOL075C, Scer\ADP1" "Cele\wht-2, Cele\wht-6, Cele\abch-1" - "Mmus\Abcg1, Mmus\Abcg5, Mmus\Abcg4" "Hsap\ABCG1, Hsap\ABCG4, Hsap\ABCG5" "viable,fertile" FBgn0041595 l(2)SK1 lethal (2) SK1 http://flybase.org/reports/FBgn0041595 gene - - - l(2)SK1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000704 fltJ flight defective J http://flybase.org/reports/FBgn0000704 - gene - - - fltJ - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0038508 CG5866 - http://flybase.org/reports/FBgn0038508 protein_coding_gene - - - CG5866 - CG5866 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC15900 K -0.038468962 -0.736576263 -0.392729477 -0.0490764 1.512516356 0.905920438 FBgn0259184 CG42288 - http://flybase.org/reports/FBgn0259184 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from sequence model "CG13353, CG42288" - CG42288 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052351 S-Lap2 Sperm-Leucylaminopeptidase 2 http://flybase.org/reports/FBgn0052351 protein_coding_gene "metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356 aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "BcDNA:LP03301, anon-WO0140519.85, Lap CG32351, CG32351, S-Lap2, S-LAP 2" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG32351 11-Aug-17 DroID_v2017_08 "Drer\rfwd2, Drer\zgc:152830, Drer\npepl1, Drer\lap3" - "Cele\lap-2, Cele\lap-1" "Xtro\lap3, Xtro\rfwd2" "Mmus\Lap3, Mmus\Rfwd2, Mmus\Npepl1" "Hsap\NPEPL1, Hsap\LAP3" viable FBgn0263400 CG43446 - http://flybase.org/reports/FBgn0263400 protein_coding_gene - - - CG43446 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011011:Zinc finger, FYVE/PHD-type" CG43446 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266623 CR45130 - http://flybase.org/reports/FBgn0266623 non_protein_coding_gene - - - CR45130 - CR45130 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043977 Su(tor)321-16-5 Su(tor)321-16-5 http://flybase.org/reports/FBgn0043977 gene - - - "321-16-5, Su(tor)321-16-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051679 Tengl3 Testis EndoG-Like 3 http://flybase.org/reports/FBgn0051679 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - "CG17006, Tengl3, CG31679" "IPR001604:DNA/RNA non-specific endonuclease, IPR020821:Extracellular Endonuclease, subunit A" CG31679 11-Aug-17 DroID_v2017_08 "Drer\endog, Drer\LOC103910196, Drer\LOC100333474" Scer\NUC1 Cele\cps-6 "Xtro\exog, Xtro\endog" "Mmus\Endog, Mmus\Exog" "Hsap\ENDOG, Hsap\EXOG" "viable,fertile" FBgn0284253 LeuRS Leucyl-tRNA synthetase http://flybase.org/reports/FBgn0284253 protein_coding_gene "aminoacyl-tRNA editing activity ; GO:0002161 | inferred from electronic annotation with InterPro:IPR009008 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002300, InterPro:IPR004493, InterPro:IPR009080, InterPro:IPR015413 leucine-tRNA ligase activity ; GO:0004823 | inferred from biological aspect of ancestor with PANTHER:PTN000236210 valine-tRNA ligase activity ; GO:0004832 | inferred from biological aspect of ancestor with PANTHER:PTN000236067 leucine-tRNA ligase activity ; GO:0004823 | traceable author statement" leucyl-tRNA aminoacylation ; GO:0006429 | traceable author statement wound healing ; GO:0042060 | inferred from mutant phenotype valyl-tRNA aminoacylation ; GO:0006438 | inferred from biological aspect of ancestor with PANTHER:PTN000236067 leucyl-tRNA aminoacylation ; GO:0006429 | inferred from biological aspect of ancestor with PANTHER:PTN000236210 neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004493 aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement "CG33123, LeuRS, CG3229, anon-EST:Posey266, l(2)SH0501, l(2)SH2 0501" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002300:Aminoacyl-tRNA synthetase, class Ia, IPR004493:Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic, IPR009008:Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR013155:Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR015413:Methionyl/Leucyl tRNA synthetase" CG33123 11-Aug-17 DroID_v2017_08 "Drer\LOC100535691, Drer\larsb" Scer\CDC60 Cele\lars-1 Xtro\lars Mmus\Lars Hsap\LARS "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0000633 fas faint sausage http://flybase.org/reports/FBgn0000633 FBgn0010603 protein_coding_gene - head involution ; GO:0008258 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | traceable author statement cardioblast cell fate determination ; GO:0007510 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | traceable author statement morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype maintenance of polarity of embryonic epithelium ; GO:0042250 | traceable author statement salivary gland development ; GO:0007431 | inferred from mutant phenotype - "CT39263, l(2)5488, l(2)05488, CG17716, fas" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG17716 11-Aug-17 DroID_v2017_08 "Drer\alcamb, Drer\alcama, Drer\bcam" - - - - - "viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "interface glial cell,aCC neuron,pCC neuron,MP1 neuron,dMP2 neuron,vMP2 neuron,Malpighian tubule primordium,Malpighian tubule,presumptive embryonic/larval digestive system,embryonic/larval foregut,embryonic/larval proventriculus,midgut constriction,embryonic head,dorsal closure embryo,embryonic epidermis,embryonic/larval salivary gland,embryonic/larval posterior spiracle,adult salivary gland primordium,cardioblast,embryonic/larval pericardial cell,external sensory organ,trichogen cell,tormogen cell,eo neuron,ventral nerve cord,ventral nerve cord commissure,ventral midline,embryonic/first instar larval cuticle,embryonic/larval esophagus,keyhole structure,embryonic/larval hindgut" FBgn0020391 Nrk Neurospecific receptor kinase http://flybase.org/reports/FBgn0020391 "FBgn0021861, FBgn0022790, FBgn0082206" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR016247, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from sequence or structural similarity" transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from electronic annotation with InterPro:IPR016247 protein phosphorylation ; GO:0006468 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys signal transduction ; GO:0007165 | inferred from direct assay rhabdomere development ; GO:0042052 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "CG4007, DmHD-434, Dnrk, nrtk_dros, DNRK, l(2)k14301, HD-434, anon-WO2004063362.79, Nrk, ROR2, nrk" "IPR018056:Kringle, conserved site, IPR000001:Kringle, IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013806:Kringle-like fold, IPR016247:Tyrosine-protein kinase, receptor ROR, IPR017441:Protein kinase, ATP binding site, IPR020067:Frizzled domain, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG4007 11-Aug-17 DroID_v2017_08 Drer\musk - Cele\cam-1 "Xtro\ror2, Xtro\ror1, Xtro\musk" "Mmus\Ror2, Mmus\Hgf, Mmus\Kremen2, Mmus\Musk, Mmus\Plat, Mmus\F2, Mmus\Hgfac" "Hsap\PLG, Hsap\PLAT, Hsap\ROR1, Hsap\HGF, Hsap\HABP2, Hsap\MUSK, Hsap\KREMEN2, Hsap\HGFAC" " embryonic stage -- adult stage , embryonic stage | stage >=10 , embryonic stage | stage 17 " " neurogenic region

, embryonic central nervous system

, peripheral nervous system

" "lethal,recessive,viable" FBgn0033614 Obp47b Odorant-binding protein 47b http://flybase.org/reports/FBgn0033614 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG13208, Obp47b, DmelObp47b" IPR006170:Pheromone/general odorant binding protein CG13208 11-Aug-17 DroID_v2017_08 - - - - Mmus\Actn4 Hsap\ACTN4 DRSC27574 K -0.569382885 0.036594396 -0.141242658 0.545977019 -1.751191302 -1.209422814 FBgn0028416 Met75Ca Met75Ca http://flybase.org/reports/FBgn0028416 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG32197, Met75Ca" - CG32197 11-Aug-17 DroID_v2017_08 - - - - - - DRSC09549 IE 1.588241685 1.251812384 1.544626368 -0.566911988 -0.583411236 -1.042212316 FBgn0036462 mRpL39 mitochondrial ribosomal protein L39 http://flybase.org/reports/FBgn0036462 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR018163 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AL353983 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AL353983 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AL353983 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9NYK5 "mRpL5, MRP-L5, CG17166, mRpL39" "IPR018163:Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR012675:Beta-grasp domain" CG17166 11-Aug-17 DroID_v2017_08 "Drer\tars2, Drer\cenpq, Drer\rprd2b, Drer\tars" "Scer\THS1, Scer\MST1, Scer\AIM10" "Cele\tars-1, Cele\mrpl-39" "Xtro\mrpl39, Xtro\tars, Xtro\tarsl2" "Mmus\Mrpl39, Mmus\Tarsl2, Mmus\Tars, Mmus\Tars2" "Hsap\TARS2, Hsap\MRPL39, Hsap\TARS, Hsap\TARSL2" "viable,visible" trichogen cell FBgn0002319 l(3)85Ec lethal (3) 85Ec http://flybase.org/reports/FBgn0002319 - gene - - - "l(3)WG89, l(3)SG39, l(3)85Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" FBgn0086368 tw twisted http://flybase.org/reports/FBgn0086368 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VTK2 dolichyl-phosphate-mannose-protein mannosyltransferase activity ; GO:0004169 | contributes_to inferred from direct assay dolichyl-phosphate-mannose-protein mannosyltransferase activity ; GO:0004169 | inferred from direct assay muscle organ development ; GO:0007517 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000006098 sarcomere organization ; GO:0045214 | inferred from genetic interaction with Dg muscle attachment ; GO:0016203 | inferred from genetic interaction with Dg lipid glycosylation ; GO:0030259 | inferred from mutant phenotype protein O-linked mannosylation ; GO:0035269 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000006098 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "Pomt2, tw, CG12311, POMT2, DPOMT2, dPOMT2, EG:34F3.7, DmPOMT2, dPomt2, Tw" "IPR003342:Glycosyl transferase family 39/83, IPR016093:MIR motif, IPR027005:Glycosyltransferase 39-like, IPR032421:Protein O-mannosyl-transferase, C-terminal four TM domain" CG12311 11-Aug-17 DroID_v2017_08 "Drer\sdf2l1, Drer\pomt1, Drer\pomt2" "Scer\PMT5, Scer\PMT4, Scer\PMT6, Scer\PMT2, Scer\PMT7, Scer\PMT3, Scer\PMT1" Cele\R12E2.13 "Xtro\pomt2, Xtro\pomt1" "Mmus\Sdf2l1, Mmus\Sdf2, Mmus\Pomt2, Mmus\Pomt1" "Hsap\POMT2, Hsap\SDF2L1, Hsap\POMT1, Hsap\SDF2" FBgn0039421 CG6036 - http://flybase.org/reports/FBgn0039421 protein_coding_gene magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR012911 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR012911 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000000891 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000000891 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000891 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000891 "PP2Cb, CG6036" "IPR000222:PPM-type phosphatase, divalent cation binding, IPR001932:PPM-type phosphatase domain, IPR012911:Protein serine/threonine phosphatase 2C, C-terminal, IPR015655:Protein phosphatase 2C family" CG6036 11-Aug-17 DroID_v2017_08 "Drer\ppm1bb, Drer\ppm1aa, Drer\ppm1ba, Drer\ppm1g, Drer\ppm1ab, Drer\ppm1na, Drer\ppm1nb" "Scer\PTC3, Scer\PTC2" "Cele\F42G9.1, Cele\ppm-1, Cele\ppm-2" "Xtro\ppm1b, Xtro\ppm1a" "Mmus\Ppm1b, Mmus\Ppm1a, Mmus\Ppm1g, Mmus\Ppm1n" "Hsap\PPM1B, Hsap\PPM1G, Hsap\PPM1N, Hsap\PPM1A" viable DRSC15953 E 1.142935774 0.347711612 0.50088674 1.54585224 -0.059358432 -1.013672335 FBgn0015882 anon-64Bd anon-64Bd http://flybase.org/reports/FBgn0015882 - gene - - - anon-64Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " leg

, adult head

, antenna

" FBgn0265104 CR44206 - http://flybase.org/reports/FBgn0265104 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44206, CR44206, pri-mir-184" - CR44206 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033249 CG11191 - http://flybase.org/reports/FBgn0033249 protein_coding_gene - - - CG11191 IPR015943:WD40/YVTN repeat-like-containing domain CG11191 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC28710 K -0.741731338 -0.235065846 0.453517938 -0.425222631 1.759052613 0.816105004 FBgn0017384 l(1)15Fa lethal (1) 15Fa http://flybase.org/reports/FBgn0017384 - gene - - - l(1)15Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058174 CG40174 - http://flybase.org/reports/FBgn0058174 protein_coding_gene - - - CG40174 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263878 l(3)LVC73 - http://flybase.org/reports/FBgn0263878 gene - - - l(3)LVC73 - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of P-stage,recessive,some die during P-stage" "embryonic/larval neuroblast,embryonic/larval brain,embryonic/larval optic lobe" FBgn0058225 CG40225 - http://flybase.org/reports/FBgn0058225 protein_coding_gene - - - CG40225 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034144 CG5089 - http://flybase.org/reports/FBgn0034144 protein_coding_gene - - - "anon-WO0140519.170, CG5089" - CG5089 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030543 CG11585 - http://flybase.org/reports/FBgn0030543 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11585 - CG11585 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260460 mRpS34 mitochondrial ribosomal protein S34 http://flybase.org/reports/FBgn0260460 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82930 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82930 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82930 "MRP-S34, CG13037, mRpS34, CG42648" IPR032053:Mitochondrial 28S ribosomal protein S34 CG42648 11-Aug-17 DroID_v2017_08 Drer\mrps34 - Cele\mrps-34 Xtro\mrps34 Mmus\Mrps34 Hsap\MRPS34 "viable,visible" trichogen cell FBgn0005705 l(1)TK108 lethal (1) TK108 http://flybase.org/reports/FBgn0005705 - gene - - - "l108, l(1)TK108" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0053054 CG33054 - http://flybase.org/reports/FBgn0053054 protein_coding_gene purine nucleoside binding ; GO:0001883 | inferred from sequence or structural similarity with HGNC:21257 purine nucleoside metabolic process ; GO:0042278 | inferred from sequence or structural similarity with HGNC:21257 cellular_component ; GO:0005575 | no biological data available "CG10517, CG10167, CG33054" IPR002589:Macro domain CG33054 11-Aug-17 DroID_v2017_08 "Drer\zgc:113436, Drer\oard1" Scer\POA1 "Cele\W08F4.12, Cele\fbxb-37, Cele\F54G2.2" - Mmus\Oard1 Hsap\OARD1 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0038499 Brf Brf http://flybase.org/reports/FBgn0038499 protein_coding_gene TFIIIB-type transcription factor activity ; GO:0001026 | inferred from electronic annotation with InterPro:IPR029529 TBP-class protein binding ; GO:0017025 | inferred from electronic annotation with InterPro:IPR013150 transcription factor binding ; GO:0008134 | inferred from physical interaction with Trf core promoter sequence-specific DNA binding ; GO:0001046 | contributes_to inferred from physical interaction with Trf DNA-templated transcriptional preinitiation complex assembly ; GO:0070897 | inferred from electronic annotation with InterPro:IPR000812 transcription from RNA polymerase III promoter ; GO:0006383 | inferred from direct assay neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of transcription from RNA polymerase III promoter ; GO:0006359 | inferred from direct assay inferred from physical interaction with Trf regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype transcription factor TFIIIB complex ; GO:0000126 | inferred from electronic annotation with InterPro:IPR029529 transcription factor complex ; GO:0005667 | inferred from physical interaction with Trf "Brf, BRF, TFIIIB, BRF1, CG5419, CG4155, CG31256, brf, Brf1" "IPR000812:Transcription factor TFIIB, IPR011665:Brf1, TBP-binding domain, IPR013137:Zinc finger, TFIIB-type, IPR013150:Transcription factor TFIIB, cyclin-like domain, IPR013763:Cyclin-like, IPR029529:Transcription factor IIIB subunit Brf1" CG31256 11-Aug-17 DroID_v2017_08 "Drer\brf2, Drer\LOC100536580, Drer\brf1b, Drer\brf1a" Scer\BRF1 Cele\brf-1 Xtro\brf1 "Mmus\Brf2, Mmus\Brf1" "Hsap\BRF1, Hsap\BRF2" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval brain FBgn0004022 Wr Wrinkle http://flybase.org/reports/FBgn0004022 - gene - - - Wr - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,recessive,developmental rate defective" wing FBgn0063925 Jra::kay Jra::kay http://flybase.org/reports/FBgn0063925 engineered_fusion_gene - - - Jra::kay - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266252 CR44947 - http://flybase.org/reports/FBgn0266252 non_protein_coding_gene - - - "CR44947, lincRNA.822" - CR44947 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266577 CR45108 - http://flybase.org/reports/FBgn0266577 non_protein_coding_gene - - - CR45108 - CR45108 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036661 CG9705 - http://flybase.org/reports/FBgn0036661 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002059 mRNA 3'-UTR binding ; GO:0003730 | inferred from biological aspect of ancestor with PANTHER:PTN000311282 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002059 regulation of mRNA stability ; GO:0043488 | inferred from biological aspect of ancestor with PANTHER:PTN000311282 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000311282 CG9705 "IPR002059:Cold-shock protein, DNA-binding, IPR011129:Cold shock domain, IPR012340:Nucleic acid-binding, OB-fold, IPR019844:Cold-shock conserved site" CG9705 11-Aug-17 DroID_v2017_08 "Drer\lin28a, Drer\csdc2b, Drer\si:ch1073-284b18.2, Drer\ybx1, Drer\carhsp1, Drer\csdc2a" - - "Xtro\ybx1, Xtro\ybx3, Xtro\lin28b, Xtro\carhsp1, Xtro\lin28a, Xtro\csdc2, Xtro\ybx2" "Mmus\Carhsp1, Mmus\Ybx2, Mmus\Lin28a, Mmus\Csdc2, Mmus\Ybx3, Mmus\Ybx1, Mmus\Lin28b" "Hsap\CSDC2, Hsap\LIN28A, Hsap\YBX2, Hsap\YBX1, Hsap\YBX3, Hsap\LIN28B, Hsap\CARHSP1" "neuroanatomy defective,viable" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB" FBgn0024904 anon-I7114 anon-I7114 http://flybase.org/reports/FBgn0024904 - gene - - - "cDNA I7114, anon-I7114" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022711 61bis 61bis http://flybase.org/reports/FBgn0022711 - gene - - - 61bis - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017625 Eig58C Eig58C http://flybase.org/reports/FBgn0017625 - gene - - - "Eig58, Eig58C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266880 CR45341 - http://flybase.org/reports/FBgn0266880 non_protein_coding_gene - - - CR45341 - CR45341 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001535 l(1)14Ba lethal (1) 14Ba http://flybase.org/reports/FBgn0001535 - gene - - - l(1)14Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036875 CG9449 - http://flybase.org/reports/FBgn0036875 protein_coding_gene acid phosphatase activity ; GO:0003993 | inferred from sequence or structural similarity with HGNC:125 phagocytosis ; GO:0006909 | inferred from mutant phenotype dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:125 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:125 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:125 CG9449 "IPR000560:Histidine phosphatase superfamily, clade-2, IPR029630:Venom acid phosphatase Acph-1, IPR029033:Histidine phosphatase superfamily, IPR033379:Histidine acid phosphatase active site" CG9449 11-Aug-17 DroID_v2017_08 "Drer\pxylp1, Drer\acp2, Drer\acp6" - "Cele\acp-3, Cele\pho-14, Cele\pho-11, Cele\F26C11.1, Cele\acp-5, Cele\pho-13, Cele\pho-7, Cele\pho-8, Cele\pho-9, Cele\acp-6, Cele\pho-1, Cele\acp-4, Cele\acp-1, Cele\pho-5, Cele\pho-12, Cele\acp-7, Cele\ZK792.1, Cele\ZK809.9, Cele\pho-10, Cele\acp-2, Cele\pho-6, Cele\C27A2.12, Cele\pho-4" "Xtro\acp6, Xtro\acp2, Xtro\LOC100494856" "Mmus\Acp2, Mmus\Pxylp1, Mmus\Acpt, Mmus\Acp6, Mmus\Acpp" "Hsap\ACPP, Hsap\PXYLP1, Hsap\ACPT, Hsap\ACP6, Hsap\ACP2" viable FBgn0004422 gustC gustatory-defective C http://flybase.org/reports/FBgn0004422 "FBgn0001155, FBgn0001160" gene - - - "gust[x2], gusB, gustC" - - 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,recessive" FBgn0025127 su(RpII140[Z36])S2 su(RpII140[Z36])S2 http://flybase.org/reports/FBgn0025127 - gene - - - "Z36[S2], su(RpII140[Z36])S2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040768 CG13234 - http://flybase.org/reports/FBgn0040768 protein_coding_gene - - - CG13234 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036108 Cpr67Fa1 Cuticular protein 67Fa1 http://flybase.org/reports/FBgn0036108 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:RE57116, Cpr67Fa1, CG7941, DmelCpr67Fa1" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG7941 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0261456 hpo hippo http://flybase.org/reports/FBgn0261456 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 kinase activity ; GO:0016301 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with yki protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with hpo protein binding ; GO:0005515 | inferred from physical interaction with Rassf inferred from physical interaction with sav protein binding ; GO:0005515 | inferred from physical interaction with ex receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement" "regulation of apoptotic signaling pathway ; GO:2001233 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein autophosphorylation ; GO:0046777 | inferred from direct assay negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype stem cell proliferation ; GO:0072089 | inferred from direct assay regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype peptidyl-threonine phosphorylation ; GO:0018107 | inferred from direct assay regulation of protein processing ; GO:0070613 | inferred from direct assay intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ; GO:0042771 | inferred from genetic interaction with p53 R8 cell fate specification ; GO:0045464 | inferred from mutant phenotype retinal cell programmed cell death ; GO:0046666 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity ; GO:0097202 | inferred from direct assay border follicle cell migration ; GO:0007298 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of apoptotic signaling pathway ; GO:2001235 | inferred from mutant phenotype hippo signaling ; GO:0035329 | traceable author statement morphogenesis of an epithelial sheet ; GO:0002011 | inferred from mutant phenotype response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype organ growth ; GO:0035265 | inferred from direct assay eye development ; GO:0001654 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay negative regulation of glial cell proliferation ; GO:0060253 | inferred from mutant phenotype negative regulation of organ growth ; GO:0046621 | traceable author statement hippo signaling ; GO:0035329 | inferred from biological aspect of ancestor with PANTHER:PTN001220914" cytoplasm ; GO:0005737 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay "hpo, Hpo, MST, hipo, CG11228, Hippo, dMST, MST2, hippo" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR011524:SARAH domain, IPR017441:Protein kinase, ATP binding site, IPR024205:Mst1 SARAH domain" CG11228 11-Aug-17 DroID_v2017_08 Drer\stk3 "Scer\SSK2, Scer\MKK2, Scer\SPS1, Scer\SSK22, Scer\MKK1" "Cele\C01C4.3, Cele\strd-1, Cele\cst-2, Cele\cst-1" "Xtro\stk3, Xtro\stk4" "Mmus\Stk4, Mmus\Stk3" "Hsap\STK4, Hsap\STK3" larval stage | third instar imaginal disc

FBgn0002486 l(3)SG46 lethal (3) SG46 http://flybase.org/reports/FBgn0002486 - gene - - - "l(3)g21, l(3)SG46" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "ventral thoracic disc,imaginal disc" FBgn0025871 B52::tra2 B52::tra2 http://flybase.org/reports/FBgn0025871 - engineered_fusion_gene - - - "TRA-2/dSRp55, B52::tra2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035084 CG15861 - http://flybase.org/reports/FBgn0035084 protein_coding_gene - - - "CG15861, R5_2R:20832201..20832579" IPR000742:EGF-like domain CG15861 11-Aug-17 DroID_v2017_08 "Drer\megf6a, Drer\ccbe1, Drer\tnfaip6, Drer\dkk2, Drer\esm1, Drer\zgc:158328, Drer\dkk1a, Drer\scarf1, Drer\megf11, Drer\pear1, Drer\megf10, Drer\megf6b" - "Cele\Y34B4A.5, Cele\B0393.5, Cele\ZK1193.3, Cele\R09H10.5" "Xtro\tnfaip6, Xtro\megf11, Xtro\stab2" "Mmus\Megf11, Mmus\Scarf1, Mmus\Dkk2, Mmus\Esm1, Mmus\Megf10, Mmus\Egfem1, Mmus\Tnfaip6, Mmus\Megf6, Mmus\Pear1, Mmus\Dkk3, Mmus\Stab1" "Hsap\SCARF1, Hsap\MEGF6, Hsap\TNFAIP6, Hsap\PEAR1, Hsap\SCARF2, Hsap\MEGF11, Hsap\MEGF10, Hsap\DKK2" "viable,fertile" FBgn0014238 l(2)31Eu lethal (2) 31Eu http://flybase.org/reports/FBgn0014238 - gene - - - l(2)31Eu - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034580 Cht8 Chitinase 8 http://flybase.org/reports/FBgn0034580 protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR001579 chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557" "chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "Cht8, CG9357, DmCht8" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR002557:Chitin binding domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG9357 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-226m16.2, Drer\chia.1, Drer\chia.6, Drer\chia.3, Drer\srl, Drer\ovgp1, Drer\chia.2, Drer\chia.5" Scer\CTS2 "Cele\chil-24, Cele\cht-2, Cele\chil-16, Cele\cht-1, Cele\chil-3, Cele\chil-17, Cele\lmd-4, Cele\chil-5, Cele\chil-21, Cele\cht-4, Cele\chil-22, Cele\chil-20, Cele\lmd-5, Cele\chil-19, Cele\chil-7, Cele\chil-12, Cele\chil-6, Cele\chil-4, Cele\chil-13, Cele\chil-23, Cele\chil-25, Cele\cht-3, Cele\chil-9, Cele\chil-18, Cele\chil-15, Cele\chil-11, Cele\T19H5.6, Cele\chil-8, Cele\chil-1, Cele\chil-2" "Xtro\srl, Xtro\chit1, Xtro\ctbs, Xtro\chia, Xtro\LOC548945" "Mmus\Ovgp1, Mmus\Chit1, Mmus\Chil1, Mmus\Ctbs, Mmus\Chil4, Mmus\Chil5, Mmus\Chil3, Mmus\Srl, Mmus\Chil6, Mmus\Chia1" "Hsap\CHI3L1, Hsap\CHI3L2, Hsap\CHIA, Hsap\CHIT1, Hsap\SRL, Hsap\OVGP1" viable FBgn0002167 l(2)Sp9d lethal (2) Sp9d http://flybase.org/reports/FBgn0002167 - gene - - - l(2)Sp9d - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264883 CR44074 - http://flybase.org/reports/FBgn0264883 non_protein_coding_gene - - - CR44074 - CR44074 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029824 CG3726 - http://flybase.org/reports/FBgn0029824 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057, InterPro:IPR017956" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 CG3726 "IPR007889:DNA binding HTH domain, Psq-type, IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR009057:Homeobox domain-like" CG3726 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Nacc1, Mmus\Nacc2" Hsap\ZBTB9 "viable,fertile,body color defective" mesothoracic tergum FBgn0264481 CR43889 - http://flybase.org/reports/FBgn0264481 non_protein_coding_gene - - - CR43889 - CR43889 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085660 CG41500 - http://flybase.org/reports/FBgn0085660 protein_coding_gene - - - CG41500 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001437 l(1)7Be lethal (1) 7Be http://flybase.org/reports/FBgn0001437 - gene - - - "l(1)DC829, l(1)7Be" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033744 Dh44-R2 Diuretic hormone 44 receptor 2 http://flybase.org/reports/FBgn0033744 protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000832, InterPro:IPR001879, InterPro:IPR017983 diuretic hormone receptor activity ; GO:0008036 | inferred from physical interaction with Dh44 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model diuretic hormone receptor activity ; GO:0008036 | inferred from sequence or structural similarity calcitonin receptor activity ; GO:0004948 | inferred from sequence or structural similarity" cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay hormone-mediated signaling pathway ; GO:0009755 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model response to salt stress ; GO:0009651 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG13156, anon-WO0170980.104, anon-WO0170980.103, CG1315, CG12370, Dh44-R2, DH44-R2, DH-R, Dh44R2" "IPR000832:GPCR, family 2, secretin-like, IPR001879:GPCR, family 2, extracellular hormone receptor domain, IPR002001:GPCR, family 2, diuretic hormone receptor, IPR017981:GPCR, family 2-like, IPR017983:GPCR, family 2, secretin-like, conserved site" CG12370 11-Aug-17 DroID_v2017_08 "Drer\vipr1b, Drer\gipr, Drer\calcrl2, Drer\gcgra, Drer\pth1rb, Drer\calcr, Drer\calcrla, Drer\gcgrb, Drer\crhr2, Drer\calcrlb, Drer\pth2r, Drer\si:dkeyp-4h4.1, Drer\adcyap1r1b, Drer\ghrhrb, Drer\ghrhra, Drer\pth1ra, Drer\adcyap1r1a, Drer\crhr1, Drer\vipr2, Drer\ghrhr2, Drer\vipr1a" - "Cele\seb-3, Cele\pdfr-1" "Xtro\gcgr, Xtro\gipr, Xtro\vipr1, Xtro\crhr1.2, Xtro\pth2r, Xtro\pth1r, Xtro\adcyap1r1, Xtro\calcrl, Xtro\crhr1.1" "Mmus\Pth2r, Mmus\Crhr1, Mmus\Calcr, Mmus\Gipr, Mmus\Vipr2, Mmus\Crhr2, Mmus\Ghrhr, Mmus\Glp2r, Mmus\Glp1r, Mmus\Adcyap1r1, Mmus\Calcrl, Mmus\Pth1r, Mmus\Vipr1, Mmus\Sctr, Mmus\Gcgr" "Hsap\CALCRL, Hsap\GIPR, Hsap\VIPR1, Hsap\ADCYAP1R1, Hsap\GCGR, Hsap\GLP2R, Hsap\CALCR, Hsap\CRHR1-IT1-CRHR1, Hsap\GLP1R, Hsap\PTH1R, Hsap\GHRHR, Hsap\VIPR2, Hsap\SCTR, Hsap\CRHR1, Hsap\CRHR2, Hsap\PTH2R" "osmotic stress response defective,viable" FBgn0040801 CG13053 - http://flybase.org/reports/FBgn0040801 protein_coding_gene - - - CG13053 - CG13053 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0040809 CG13465 - http://flybase.org/reports/FBgn0040809 protein_coding_gene - - - CG13465 - CG13465 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263911 COX8 Cytochrome c oxidase subunit 8 http://flybase.org/reports/FBgn0263911 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from electronic annotation with InterPro:IPR003205 - - "CG7181, VIII, BcDNA:GH15688, anon-WO0118547.331, 0554/18, l(3)S055418, COX8, CoVIII, CcO VIIc" "IPR003205:Cytochrome c oxidase, subunit 8" CG7181 11-Aug-17 DroID_v2017_08 "Drer\cox8b, Drer\si:dkey-85n7.8, Drer\cox8a" - - - "Mmus\Cox8a, Mmus\Cox8c, Mmus\Cox8b" "Hsap\COX8A, Hsap\COX8C" DRSC11814 K -0.960265869 -1.106376939 -0.955817277 0.024078421 2.193120641 1.985592463 FBgn0003703 thv thick vein http://flybase.org/reports/FBgn0003703 - gene - - - thv - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male fertile,female fertile,reduced,visible,recessive,eye color defective,poor,male,body color defective" "wing,wing vein,wing vein L1,wing vein L2,eye,wing hair" FBgn0060776 l(3)S060903 lethal (3) S060903 http://flybase.org/reports/FBgn0060776 gene - - - "0609/03, l(3)S060903" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259795 loopin-1 loopin-1 http://flybase.org/reports/FBgn0259795 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "loopin-1, CG4750, anon-WO0140519.81, kl3 lp-1, kl3lp1, loopin, S-LAP 6" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG4750 11-Aug-17 DroID_v2017_08 "Drer\rfwd2, Drer\zgc:152830, Drer\npepl1, Drer\lap3" - "Cele\lap-2, Cele\lap-1" "Xtro\lap3, Xtro\rfwd2" "Mmus\Npepl1, Mmus\Rfwd2, Mmus\Lap3" "Hsap\LAP3, Hsap\NPEPL1" FBgn0013396 anon-94DEa anon-94DEa http://flybase.org/reports/FBgn0013396 - gene - - - "anon-94DE, anon-94DEa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037007 CG5059 - http://flybase.org/reports/FBgn0037007 protein_coding_gene - positive regulation of apoptotic process ; GO:0043065 | inferred from electronic annotation with InterPro:IPR010548 regulation of programmed cell death ; GO:0043067 | inferred from biological aspect of ancestor with PANTHER:PTN001032684 mitochondrial outer membrane permeabilization ; GO:0097345 | inferred from biological aspect of ancestor with PANTHER:PTN001032684 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010548 nucleus ; GO:0005634 | inferred from direct assay mitochondrial outer membrane ; GO:0005741 | inferred from biological aspect of ancestor with PANTHER:PTN001032684 "CG5059, BNIP3" IPR010548:BNIP3 CG5059 11-Aug-17 DroID_v2017_08 "Drer\bnip3, Drer\bnip3la, Drer\zgc:73226, Drer\bnip4, Drer\bnip3lb" - Cele\dct-1 Xtro\bnip3 "Mmus\Bnip3, Mmus\Bnip3l" "Hsap\BNIP3L, Hsap\BNIP3" viable FBgn0036786 skl sickle http://flybase.org/reports/FBgn0036786 protein_coding_gene - cell death ; GO:0008219 | inferred from mutant phenotype inferred from genetic interaction with rpr cell death ; GO:0008219 | inferred from mutant phenotype inferred from genetic interaction with grim apoptotic process ; GO:0006915 | inferred from direct assay cellular response to ionizing radiation ; GO:0071479 | inferred from direct assay apoptotic process ; GO:0006915 | inferred from genetic interaction with nos apoptotic process ; GO:0006915 | non-traceable author statement programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "veto, CG13701, Skl, meph, BcDNA:RE14076, skl" - CG13701 11-Aug-17 DroID_v2017_08 - - - - - - "cell death defective,viable,fertile,increased cell death" "EW3 neuron | prepupal stage,EW3 neuron,eye" FBgn0035770 pst pastrel http://flybase.org/reports/FBgn0035770 protein_coding_gene molecular_function ; GO:0003674 | no biological data available long-term memory ; GO:0007616 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "pastrel, CG8588, Dm-65, pst" IPR031962:Domain of unknown function DUF4781 CG8588 11-Aug-17 DroID_v2017_08 - - Cele\F02C12.1 - - - "memory defective,stress response defective" FBgn0004961 l(1)17Ae lethal (1) 17Ae http://flybase.org/reports/FBgn0004961 - gene - - - l(1)17Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0050231 tRNA:Phe-GAA-1-5 transfer RNA:Phenylalanine-GAA 1-5 http://flybase.org/reports/FBgn0050231 tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "AE002787.trna47-PheGAA, tRNA:F:GAA:AE002787-b, CR30107, CR30231, chr2R.trna30-PheGAA, tRNA-Phe-GAA-1-5, tRNA:Phe-GAA-1-5, tRNA:CR30231, UUC" - CR30231 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261605 M(2)34BC Minute (2) 34BC http://flybase.org/reports/FBgn0261605 gene - - - M(2)34BC - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013507 l(1)U10 lethal (1) U10 http://flybase.org/reports/FBgn0013507 - gene - - - "U-10, l(1)U10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011890 tRNA:Lys-CTT-1-5 transfer RNA:Lysine-CTT 1-5 http://flybase.org/reports/FBgn0011890 "FBgn0003795, FBgn0011886, FBgn0050315, FBgn0050515, FBgn0060188" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "35SLys, tRNA[Lys][[2]], AE002769.trna3-LysCTT, tRNA:K2, tRNA:K:CTT:AE002769-a, tRNA:lys2:42Ad, CR30315, CR30515, tRNAlys, chr2R.trna94-LysCTT, tRNA-Lys-CTT-1-5, tRNA:Lys-CTT-1-5, tRNA:K2:42Ad, AAG" - CR30515 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014850 Eig71Ej Eig71Ej http://flybase.org/reports/FBgn0014850 - protein_coding_gene - salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern metamorphosis ; GO:0007552 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 extracellular region ; GO:0005576 | inferred from sequence model "L71, L71-10, CG7588, Eig71Ej" IPR003475:Insect protein of unknown function CG7588 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267196 CR45636 - http://flybase.org/reports/FBgn0267196 non_protein_coding_gene - - - "CR45636, lincRNA.790" - CR45636 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014146 dfk distal of forkhead http://flybase.org/reports/FBgn0014146 - gene - - - "dfh, dfk" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013379 aagp armadillo-associated glycoprotein http://flybase.org/reports/FBgn0013379 - gene - - - aagp - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052432 CG32432 - http://flybase.org/reports/FBgn0052432 protein_coding_gene - - - "CG13257, CG13256, FBgn0037032, CG3116, CG32432" "IPR000859:CUB domain, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG32432 11-Aug-17 DroID_v2017_08 "Drer\ston2, Drer\ap4m1" - Cele\lev-10 - "Mmus\Ston1, Mmus\Ap4m1, Mmus\Ston2" "Hsap\STON1, Hsap\AP4M1, Hsap\STON2" "viable,fertile" FBgn0260027 CG42495 - http://flybase.org/reports/FBgn0260027 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42495 - CG42495 11-Aug-17 DroID_v2017_08 Drer\LOC100537949 - Cele\F40F8.3 - Mmus\Tmem42 Hsap\TMEM42 FBgn0034770 Obp58d Odorant-binding protein 58d http://flybase.org/reports/FBgn0034770 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG13519, Obp58d, DmelObp58d" IPR006170:Pheromone/general odorant binding protein CG13519 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0083966 CG34130 - http://flybase.org/reports/FBgn0083966 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 molecular_function ; GO:0003674 | no biological data available proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG6069, SPH192, CG34130" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34130 11-Aug-17 DroID_v2017_08 "Drer\tmprss9, Drer\zgc:55888, Drer\st14a, Drer\zmp:0000001114" - - - "Mmus\St14, Mmus\Gzma, Mmus\Gzmm, Mmus\Tmprss13" "Hsap\TMPRSS13, Hsap\GZMM, Hsap\ST14, Hsap\GZMA" viable FBgn0033689 CG18342 - http://flybase.org/reports/FBgn0033689 protein_coding_gene - - - CG18342 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002994 olfQ olfactory Q http://flybase.org/reports/FBgn0002994 - gene - - - olfQ - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015365 biz bizarre http://flybase.org/reports/FBgn0015365 - gene - thermosensory behavior ; GO:0040040 | inferred from mutant phenotype - "SB8, biz" - - 11-Aug-17 DroID_v2017_08 - - - - - - "hypoactive,behavior defective" FBgn0044511 mRpS21 mitochondrial ribosomal protein S21 http://flybase.org/reports/FBgn0044511 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82921 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82921 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82921 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "MRP-S21, BcDNA:RE23482, CG32854, MrpS21, mRpS21" IPR001911:Ribosomal protein S21 CG32854 11-Aug-17 DroID_v2017_08 Drer\mrps21 - Cele\mrps-21 Xtro\mrps21 Mmus\Mrps21 Hsap\MRPS21 "viable,visible" trichogen cell DRSC21357 E -0.426059269 0.32651795 0.308568485 -1.556125223 -0.104345499 0.23009066 FBgn0035009 CG16837 - http://flybase.org/reports/FBgn0035009 protein_coding_gene "dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay dynein complex ; GO:0030286 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 CG16837 IPR004942:Roadblock/LAMTOR2 domain CG16837 11-Aug-17 DroID_v2017_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb2, Mmus\Dynlrb1" "Hsap\DYNLRB2, Hsap\DYNLRB1" viable DRSC04283 E 0.340083742 -0.00982863 0.106799039 -1.588708857 -0.165432031 0.560633672 FBgn0002991 olfB olfactory B http://flybase.org/reports/FBgn0002991 - gene - - - olfB - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,smell perception defective,recessive,heat sensitive,viable" FBgn0016684 NaPi-T Na[+]-dependent inorganic phosphate cotransporter http://flybase.org/reports/FBgn0016684 - protein_coding_gene phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from electronic annotation with InterPro:IPR004745 transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 phosphate ion transmembrane transport ; GO:0035435 | inferred from electronic annotation with InterPro:IPR004745 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 "Dropo, Na/Pi-cotransporter, CG10207, NaPi-T, NapiT, MFS2, Na[+]-dependent inorganic phosphate cotransporter" "IPR004745:Na-dependent inorganic phosphate cotransporter, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG10207 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-513e17.1, Drer\slc17a5" "Scer\YIL166C, Scer\DAL5, Scer\THI73, Scer\TNA1" "Cele\T22F3.11, Cele\F56A4.12, Cele\Y51B9A.6, Cele\slc-17.9, Cele\Y19D10A.11, Cele\C18H9.5, Cele\D1046.4, Cele\slc-17.8, Cele\T02B11.6, Cele\Y4C6B.4, Cele\C18D1.2, Cele\C01B4.8, Cele\T28H11.8, Cele\M117.1, Cele\Y19D10A.4, Cele\F10C2.7, Cele\slc-17.6, Cele\F59A1.13, Cele\slc-17.3, Cele\C39E9.7, Cele\K08C7.1, Cele\slc-17.2, Cele\F56A4.10, Cele\M162.5, Cele\T19D12.10, Cele\F41C3.2, Cele\F44E7.7, Cele\K11G9.5, Cele\C01B4.7, Cele\R10D12.1, Cele\slc-17.4, Cele\T27D12.1, Cele\W04C9.6, Cele\Y15E3A.4, Cele\slc-17.1, Cele\slc-17.5, Cele\F11A5.9, Cele\T19D12.9, Cele\Y19D10A.5, Cele\slc-17.7, Cele\cima-1, Cele\T22F3.7, Cele\Y19D10A.8, Cele\T22F3.8, Cele\Y4C6B.3, Cele\H11E01.2, Cele\T01H3.3, Cele\T22F3.10, Cele\C35A5.3" - "Mmus\Slc17a1, Mmus\Slc17a3, Mmus\Slc17a4, Mmus\Slc17a2, Mmus\Slc17a5" "Hsap\SLC17A4, Hsap\SLC17A1, Hsap\SLC17A5, Hsap\SLC17A2, Hsap\SLC17A3" "viable,fertile" FBgn0030980 CG7406 - http://flybase.org/reports/FBgn0030980 protein_coding_gene - - - CG7406 IPR031903:Domain of unknown function DUF4766 CG7406 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264645 flash-flood flash flood http://flybase.org/reports/FBgn0264645 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - flash-flood - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval lateral trunk,eye,somatic clone" FBgn0000073 Ama-2 alpha Amanitin-resistant 2 http://flybase.org/reports/FBgn0000073 - gene - - - Ama-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260577 MENE-X46 - http://flybase.org/reports/FBgn0260577 gene - - - MENE-X46 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye disc,somatic clone" FBgn0019745 l(1)83B lethal (1) 83B http://flybase.org/reports/FBgn0019745 - gene - - - l(1)83B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021799 l(2)k16919 lethal (2) k16919 http://flybase.net/reports/FBgn0021799.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0021847 l(2)k14710 lethal (2) k14710 http://flybase.org/reports/FBgn0021847 FBgn0027519 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "l(2)k15603, CG8325, BcDNA:LD21719, l(2)k14710" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG8325 11-Aug-17 DroID_v2017_08 "Drer\ttc7a, Drer\ttc7b, Drer\ttc34" - Cele\ttc-7 "Xtro\ttc7b, Xtro\ttc7a" "Mmus\Ttc7, Mmus\Ttc34, Mmus\Ttc7b" "Hsap\TTC7A, Hsap\TTC7B, Hsap\TTC34" "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0058362 CG40362 - http://flybase.org/reports/FBgn0058362 protein_coding_gene - - - CG40362 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051583 tRNA:Asn-GTT-1-10 transfer RNA:Asparagine-GTT 1-10 http://flybase.org/reports/FBgn0051583 tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "AE002708.trna67-AsnGTT, tRNA:asn5:84Fc, tRNA:N5:84Fc, tRNA:asn5:84Fb, tRNA:N5:84Fb, tRNA:asn5:84Fa, tRNA:N5:84Fa, tRNA:N:GTT:AE002708, CR31583, chr3R.trna73-AsnGTT, tRNA:Asn-GTT-1-10, tRNA:N5:84F, tRNA-Asn-GTT-1-10, AAC" - CR31583 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264942 CR44111 - http://flybase.org/reports/FBgn0264942 non_protein_coding_gene - - - CR44111 - CR44111 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263957 BG01121 - http://flybase.org/reports/FBgn0263957 gene - - - BG01121 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective,female limited" FBgn0039150 CG13605 - http://flybase.org/reports/FBgn0039150 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13605 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13605 11-Aug-17 DroID_v2017_08 "Drer\chfr, Drer\rnft1, Drer\rnf145b, Drer\rnf145a, Drer\syvn1, Drer\zmp:0000000662, Drer\amfr, Drer\rnft2, Drer\rnf151" "Scer\HRD1, Scer\SAN1" Cele\ZC13.1 "Xtro\chfr, Xtro\rnft2, Xtro\rnf139, Xtro\amfr, Xtro\rnft1, Xtro\LOC100127651, Xtro\rnf145, Xtro\syvn1" "Mmus\Trim69, Mmus\Amfr, Mmus\Chfr, Mmus\Rnf151, Mmus\Rnf145, Mmus\Rnft2, Mmus\Rnf139, Mmus\Rnft1, Mmus\Syvn1" "Hsap\RNFT1, Hsap\TRIM69, Hsap\SYVN1, Hsap\CHFR, Hsap\RNF151, Hsap\RNF145, Hsap\RNFT2, Hsap\AMFR, Hsap\RNF139" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260461 Rcd7 Reduction in Cnn dots 7 http://flybase.org/reports/FBgn0260461 protein_coding_gene - centrosome separation ; GO:0051299 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "Rcd7, CG14098" - CG14098 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable" FBgn0032057 CG9287 - http://flybase.org/reports/FBgn0032057 protein_coding_gene - - - CG9287 "IPR029058:Alpha/Beta hydrolase fold, IPR002018:Carboxylesterase, type B" CG9287 11-Aug-17 DroID_v2017_08 "Drer\cell, Drer\ces3, Drer\ces2, Drer\nlgn2a, Drer\si:ch211-93f2.1, Drer\cel.1, Drer\nlgn4b, Drer\nlgn3b, Drer\nlgn3a, Drer\nlgn4a, Drer\nlgn1, Drer\nlgn2b" - "Cele\K07C11.4, Cele\ges-1, Cele\glit-1, Cele\Y71H2AM.13, Cele\T28C12.4, Cele\F07C4.12, Cele\R173.3, Cele\K11G9.2, Cele\F56C11.6, Cele\F15A8.6" "Xtro\ces2, Xtro\nlgn2, Xtro\LOC100494782, Xtro\nlgn3, Xtro\cel, Xtro\ces3, Xtro\nlgn4x" "Mmus\Ces2e, Mmus\Ces2h, Mmus\Tg, Mmus\Ces3b, Mmus\Ces2g, Mmus\Nlgn3, Mmus\Nlgn2, Mmus\Ces2f, Mmus\Ces3a, Mmus\Ces1b, Mmus\Cel, Mmus\Ces1h, Mmus\Ces4a, Mmus\Ces2b, Mmus\Ces1c, Mmus\Ces5a, Mmus\Ces2c, Mmus\Ces2a, Mmus\Ces1g, Mmus\Ces1e, Mmus\Nlgn1, Mmus\Ces1f, Mmus\Ces1d" "Hsap\NLGN4X, Hsap\CES4A, Hsap\CES1, Hsap\NLGN2, Hsap\NLGN4Y, Hsap\TG, Hsap\CEL, Hsap\CES2, Hsap\NLGN1, Hsap\CES5A, Hsap\CES3, Hsap\NLGN3" "viable,fertile" DRSC03186 I 1.589024852 0.594379983 0.476441683 0.342074121 0.391241399 0.64305324 FBgn0001486 l(1)10Af lethal (1) 10Af http://flybase.org/reports/FBgn0001486 - gene - - - "l(1)EM16, l(1)G11, l(1)EF444, l(1)10Af" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "ovariole,germline clone,maternal effect" FBgn0034276 Sardh Sarcosine dehydrogenase http://flybase.org/reports/FBgn0034276 protein_coding_gene sarcosine dehydrogenase activity ; GO:0008480 | inferred from biological aspect of ancestor with PANTHER:PTN001014783 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR023753 sarcosine catabolic process ; GO:1901053 | inferred from mutant phenotype S-adenosylmethionine cycle ; GO:0033353 | inferred from mutant phenotype" mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN002302636 "CG6385, Sardh, sardh" "IPR006076:FAD dependent oxidoreductase, IPR006222:Glycine cleavage T-protein-like, N-terminal, IPR013977:Glycine cleavage T-protein, C-terminal barrel domain, IPR029043:Glycine cleavage T-protein/YgfZ, C-terminal domain, IPR032503:FAD dependent oxidoreductase, central domain, IPR023753:FAD/NAD(P)-binding domain" CG6385 11-Aug-17 DroID_v2017_08 "Drer\dmgdh, Drer\pdpr, Drer\sardh" Scer\GCV1 Cele\Y37E3.17 "Xtro\pdpr, Xtro\sardh, Xtro\dmgdh" "Mmus\Pdpr, Mmus\Dmgdh, Mmus\Sardh" "Hsap\DMGDH, Hsap\PDPR, Hsap\SARDH" viable FBgn0060691 l(3)S073414 lethal (3) S073414 http://flybase.org/reports/FBgn0060691 gene - - - "0734/14, l(3)S073414" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0037939 CG14718 - http://flybase.org/reports/FBgn0037939 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg14718, CG14718" "IPR000504:RNA recognition motif domain, IPR001876:Zinc finger, RanBP2-type" CG14718 11-Aug-17 DroID_v2017_08 "Drer\ewsr1b, Drer\ewsr1a, Drer\fus, Drer\taf15" - "Cele\fust-1, Cele\Y65B4A.1" "Xtro\ewsr1, Xtro\fus, Xtro\taf15" "Mmus\Taf15, Mmus\Fus, Mmus\Ewsr1" "Hsap\TAF15, Hsap\FUS, Hsap\EWSR1" viable FBgn0266988 CR45439 - http://flybase.org/reports/FBgn0266988 non_protein_coding_gene - - - CR45439 - CR45439 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264514 CR43913 - http://flybase.org/reports/FBgn0264514 non_protein_coding_gene - - - "CR43913, lincRNA.537" - CR43913 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034576 ND-B14.7 NADH dehydrogenase (ubiquinone) B14.7 subunit http://flybase.org/reports/FBgn0034576 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with HGNC:20371 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN001085916 "BcDNA:RH51452, CG9350, ND-B14.7" - CG9350 11-Aug-17 DroID_v2017_08 Drer\ndufa11 - - Xtro\ndufa11 Mmus\Ndufa11 Hsap\NDUFA11 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC04544 IE -0.396405947 -2.465681724 -2.716906957 0.192276773 1.489031791 0.538901356 FBgn0267884 CR46172 - http://flybase.org/reports/FBgn0267884 pseudogene_attribute - - - "CR46172, CG12717-related" - CR46172 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082371 EP2522 EP2522 http://flybase.org/reports/FBgn0082371 gene - - - EP2522 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0058330 CG40330 - http://flybase.org/reports/FBgn0058330 protein_coding_gene - - - CG40330 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263116 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B http://flybase.org/reports/FBgn0263116 protein_coding_gene G-protein coupled serotonin receptor activity ; GO:0004993 | traceable author statement Gi/o-coupled serotonin receptor activity ; GO:0001586 | non-traceable author statement neurotransmitter receptor activity ; GO:0030594 | inferred from biological aspect of ancestor with PANTHER:PTN000664111 G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from direct assay G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from sequence or structural similarity G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity serotonin receptor signaling pathway ; GO:0007210 | inferred from direct assay adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | inferred from direct assay phospholipase C-activating serotonin receptor signaling pathway ; GO:0007208 | traceable author statement adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | traceable author statement serotonin receptor signaling pathway ; GO:0007210 | inferred from sequence or structural similarity entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype phospholipase C-activating serotonin receptor signaling pathway ; GO:0007208 | inferred from direct assay "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "5-HT1B, CG30126, CG15113, Dm5HTdro2B, 5HT-dro2B, 5-HT[[1BDro]], 5-HT-dro2B, DRO2B, 5htdro2b, 5-HT[[dro2B]], 5-HT1BDro, 5HT-dro[[2B]], 5HT-R2B, d5-HT1B, 5HT1B, 5-HT[1B]Dro, 5-HT[[1B]], 5-HT[[1B]]Dro, 5-HT[[1B]]DRO, HT1B, 5HT1b" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG15113 11-Aug-17 DroID_v2017_08 "Drer\or137-3, Drer\htr1fb, Drer\LOC100330650, Drer\htr1ab, Drer\htr1d, Drer\or137-2, Drer\or135-1, Drer\or137-7, Drer\htr1b, Drer\htr5ab, Drer\si:dkeyp-3f10.14, Drer\or132-4, Drer\si:dkey-92k1.9, Drer\or137-8, Drer\or132-3, Drer\si:dkeyp-3f10.12, Drer\or136-1, Drer\or133-1, Drer\si:dkeyp-3f10.11, Drer\htr5aa, Drer\or132-5, Drer\or137-9, Drer\htr1aa, Drer\or132-1, Drer\adra2a, Drer\or134-1, Drer\or137-4, Drer\or132-2, Drer\or137-5, Drer\htr1e, Drer\or137-1, Drer\htr1fa" - "Cele\ser-7, Cele\octr-1, Cele\ser-4, Cele\ser-2" "Xtro\htr1b, Xtro\htr1f, Xtro\htr1a, Xtro\htr5a" "Mmus\Adra2a, Mmus\Htr1b, Mmus\Lpar2, Mmus\Htr1d, Mmus\Htr7, Mmus\Htr5b, Mmus\Htr5a, Mmus\Htr1a, Mmus\Htr1f" "Hsap\ADRA2A, Hsap\HTR1E, Hsap\HTR5A, Hsap\HTR1D, Hsap\HTR7, Hsap\HTR1F, Hsap\HTR1B, Hsap\HTR1A, Hsap\LPAR2" " embryonic stage | stage 16,17 " " bipolar dendrite neuron

, ventral midline

" FBgn0063381 snoRNA:Me28S-G3081a - http://flybase.org/reports/FBgn0063381 snoRNA_gene - - - "U31snoRNA, CR32887, snoRNA:Me28S-G3081a, Me28S-G3081a(U31), snoRNA:U31:54Ea, DmSnR67, Dm_28S.041" - CR32887 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259555 GG01052 - http://flybase.org/reports/FBgn0259555 gene - - - GG01052 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "unguis,leg,mesothoracic tergum,arista,eye,wing margin" FBgn0029936 CG4617 - http://flybase.org/reports/FBgn0029936 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4617, CC28" IPR009071:High mobility group box domain CG4617 11-Aug-17 DroID_v2017_08 Drer\hmgxb4a "Scer\HMO1, Scer\IXR1" - Xtro\hmgxb4 "Mmus\A530032D15Rik, Mmus\Sp110, Mmus\Hmgxb4" "Hsap\HMGXB4, Hsap\SP140, Hsap\SP140L, Hsap\SP110" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0003336 scp scooped http://flybase.org/reports/FBgn0003336 - gene - - - scp - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0031723 CG7251 - http://flybase.org/reports/FBgn0031723 protein_coding_gene - - - "bs11h10.y1, anon-WO0140519.103, CG7251" - CG7251 11-Aug-17 DroID_v2017_08 "Drer\LOC103909961, Drer\zgc:153293" - - - Mmus\Ccdc34 Hsap\CCDC34 viable FBgn0036459 CG3349 - http://flybase.org/reports/FBgn0036459 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model CG3349 - CG3349 11-Aug-17 DroID_v2017_08 Drer\mccc2 Scer\NDC80 - - Mmus\Mccc2 Hsap\MCCC2 viable FBgn0039714 Zip99C Zinc/iron regulated transporter-related protein 99C http://flybase.org/reports/FBgn0039714 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred from biological aspect of ancestor with PANTHER:PTN000424313 zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016323 iron ion transmembrane transporter activity ; GO:0005381 | inferred from direct assay zinc II ion transmembrane transport ; GO:0071577 | inferred from biological aspect of ancestor with PANTHER:PTN000424313 multicellular organismal iron ion homeostasis ; GO:0060586 | inferred from mutant phenotype detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype iron ion transport ; GO:0006826 | inferred from mutant phenotype cellular zinc ion homeostasis ; GO:0006882 | inferred from biological aspect of ancestor with PANTHER:PTN000424313 basolateral plasma membrane ; GO:0016323 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG7816, dZip99C, dZip13, Zip99C, cg7816, dZIP13" IPR003689:Zinc/iron permease CG7816 11-Aug-17 DroID_v2017_08 Drer\slc39a13 Scer\YKE4 "Cele\C14H10.1, Cele\hke-4.1, Cele\hke-4.2" Xtro\slc39a13 "Mmus\Slc39a7, Mmus\Slc39a13" "Hsap\SLC39A13, Hsap\SLC39A7" viable FBgn0265961 CR44748 - http://flybase.org/reports/FBgn0265961 non_protein_coding_gene - - - CR44748 - CR44748 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065978 iab-7E.s iab-7E.s http://flybase.org/reports/FBgn0065978 gene - - - "7E-s, iab-7E.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265368 CR44309 - http://flybase.org/reports/FBgn0265368 non_protein_coding_gene - - - "CR44309, lincRNA.24" - CR44309 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002381 l(3)93Ca lethal (3) 93Ca http://flybase.org/reports/FBgn0002381 - gene - - - "er6, l(3)er6, l(3)93Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001139 gro groucho http://flybase.org/reports/FBgn0001139 "FBgn0019999, FBgn0020008, FBgn0023439, FBgn0043006, FBgn0043009, FBgn0062049" protein_coding_gene transcription factor binding ; GO:0008134 | inferred from physical interaction with dl transcription corepressor activity ; GO:0003714 | inferred from direct assay repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with cic CRD domain binding ; GO:0071906 | inferred from physical interaction with UniProtKB:Q9UJU2 repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with retn protein binding ; GO:0005515 | inferred from physical interaction with kni HMG box domain binding ; GO:0071837 | inferred from physical interaction with UniProtKB:Q9UJU2 repressing transcription factor binding ; GO:0070491 | inferred from genetic interaction with E(spl)m7-HLH repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with hkb RNA polymerase II transcription corepressor activity ; GO:0001106 | inferred from genetic interaction with E(spl)m7-HLH transcription factor binding ; GO:0008134 | inferred from physical interaction with HGTX transcription factor binding ; GO:0008134 | inferred from mutant phenotype DNA binding ; GO:0003677 | NOT non-traceable author statement transcription corepressor activity ; GO:0003714 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Myc protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P91943 inferred from physical interaction with UniProtKB:Q01196-1 inferred from physical interaction with UniProtKB:Q01196-2 inferred from physical interaction with UniProtKB:Q13761 transcription factor binding ; GO:0008134 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with h transcription factor binding ; GO:0008134 | inferred from physical interaction with h inferred from physical interaction with E(spl)m7-HLH protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P14003 transcription corepressor activity ; GO:0003714 | traceable author statement transcription corepressor activity ; GO:0003714 | inferred from physical interaction with h transcription factor binding ; GO:0008134 | inferred from physical interaction with so protein binding ; GO:0005515 | inferred from physical interaction with elB "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype inferred from genetic interaction with kni dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from physical interaction with h sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with Myc negative regulation of Wnt signaling pathway ; GO:0030178 | non-traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from genetic interaction with h actin filament organization ; GO:0007015 | inferred from mutant phenotype negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from direct assay nervous system development ; GO:0007399 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR009146 protein complex ; GO:0043234 | inferred from physical interaction with Myc nucleus ; GO:0005634 | traceable author statement "CG8384, gro, Gro, E(spl)gro, dGro, dAES1, dAES2, BcDNA.LD33829, E(spl)[2], l(3)gro, m9, m9/10, m9-m10, m9/m10, E(spl)-WD, E(spl)m9/m10, m10, m9,m10, BEST:LD15161, BEST:GM01575, En-spl, BcDNA:LD33829, anon-WO0118547.385, Groucho, GRO, Grg/TLE, DGro, groucho" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR005617:Groucho/TLE, N-terminal Q-rich domain, IPR009146:Groucho/transducin-like enhancer, IPR019775:WD40 repeat, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like" CG8384 11-Aug-17 DroID_v2017_08 "Drer\aes, Drer\tle3a, Drer\si:dkey-42p8.3, Drer\zgc:136336, Drer\tle3b, Drer\tle2, Drer\chico" Scer\TUP1 "Cele\wdr-5.3, Cele\eya-1, Cele\unc-37, Cele\wdr-48" "Xtro\tle1, Xtro\tle2, Xtro\tle4, Xtro\aes" "Mmus\Aes, Mmus\Tle4, Mmus\Tle2, Mmus\Tle6, Mmus\Tle1, Mmus\Gm21964, Mmus\Tle3" "Hsap\TLE6, Hsap\TLE4, Hsap\AES, Hsap\TLE1, Hsap\TLE3, Hsap\TLE2" " embryonic stage | 2-6 hr , adult stage | female , embryonic stage | early , embryonic stage , embryonic stage | stage <=11 " " central nervous system

, embryonic peripheral nervous system

,

ubiquitous " "lethal,recessive,embryonic/larval segmentation phenotype,maternal effect,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,lethal - all die before end of P-stage,some die during pharate adult stage,neurogenic phenotype,viable,wild-type,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority live,dominant,female sterile,partially,male sterile,somatic clone,partially lethal - majority die" "filzkorper,maternal effect,larval head,intermediate ventral neurectoderm,eye,eye photoreceptor cell & eye-antennal discey.PH,eye-antennal disc | late third instar larval stage,head capsule,embryonic/first instar larval cuticle,wing,wing vein L4,wing vein L5,wing margin,wing vein,leg,denticle belt,ocellus,adult head & microchaeta,wing vein L1,wing vein L2,wing vein L3,anterior compartment,dorsal/ventral compartment boundary,macrochaeta & head,macrochaeta & thorax,macrochaeta & abdominal tergite,microchaeta & head,microchaeta & thorax,microchaeta & abdominal tergite,frontal bristle,supernumerary,germline clone,photoreceptor cell,somatic clone,dendrite,sense organ & wing,microchaeta & scutum,macrochaeta & scutum,macrochaeta,ventral nerve cord primordium,ommatidium,embryonic gnathal segment,embryonic epidermis,chaeta,ectopic,mesothoracic tergum,microchaeta,scutellum,anterior postalar bristle,mesothoracic tergum & macrochaeta-C253,sensory mother cell" FBgn0036892 Lon Lon protease http://flybase.org/reports/FBgn0036892 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR004815, InterPro:IPR027065 mitochondrial light strand promoter anti-sense binding ; GO:0070361 | inferred from biological aspect of ancestor with PANTHER:PTN000005479 ATP-dependent peptidase activity ; GO:0004176 | inferred from biological aspect of ancestor with PANTHER:PTN002464028 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence or structural similarity with UniProtKB:P36776" mitochondrion organization ; GO:0007005 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype misfolded or incompletely synthesized protein catabolic process ; GO:0006515 | inferred from biological aspect of ancestor with PANTHER:PTN002464028 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000005479 mitochondrion ; GO:0005739 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:20598 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P36776 "anon-WO0118547.350, CG8798, Lon" "IPR003111:Lon, substrate-binding domain, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR004815:Lon protease, bacterial/eukaryotic-type, IPR008268:Peptidase S16, active site, IPR027503:Lon protease homolog, chloroplastic/mitochondrial, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027065:Lon protease, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR008269:Peptidase S16, Lon proteolytic domain, IPR015947:PUA-like domain" CG8798 11-Aug-17 DroID_v2017_08 "Drer\lonp1, Drer\lonp2" Scer\PIM1 "Cele\lonp-1, Cele\lonp-2, Cele\T23G4.2" "Xtro\lonp2, Xtro\lonp1" "Mmus\Lonp1, Mmus\Lonp2" "Hsap\LONP2, Hsap\LONP1" "developmental rate defective,RU486 conditional,short lived,male,female,viable,visible" trichogen cell DRSC11049 I -2.01838158 -0.017784196 0.305652778 -0.284613394 0.451557122 -0.237235623 FBgn0002928 Ne Nelson's mutant http://flybase.org/reports/FBgn0002928 - gene - - - Ne - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,female,maternal effect,recessive,some die during embryonic stage" FBgn0003879 tu(2)W tumor(2)W http://flybase.org/reports/FBgn0003879 - gene - - - "tu-W, tu(2)W" - - 11-Aug-17 DroID_v2017_08 - - - - - - melanotic mass phenotype FBgn0002152 l(2)KX152 lethal (2) KX152 http://flybase.org/reports/FBgn0002152 - gene - - - l(2)KX152 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265339 CR44293 - http://flybase.org/reports/FBgn0265339 non_protein_coding_gene - - - CR44293 - CR44293 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267080 CR45524 - http://flybase.org/reports/FBgn0267080 non_protein_coding_gene - - - CR45524 - CR45524 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023158 Su(mg)2-1 Suppressor of modifier of gypsy 2-1 http://flybase.org/reports/FBgn0023158 - gene - - - Su(mg)2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035248 CG13919 - http://flybase.org/reports/FBgn0035248 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13919 IPR019396:Transmembrane Fragile-X-F-associated protein CG13919 11-Aug-17 DroID_v2017_08 "Drer\tmem60, Drer\tmem185" - - "Xtro\tmem60, Xtro\tmem185a" "Mmus\Tmem60, Mmus\Tmem185a" "Hsap\TMEM185A, Hsap\TMEM185B, Hsap\TMEM60" viable FBgn0030573 nmdyn-D6 nmdyn-D6 http://flybase.org/reports/FBgn0030573 protein_coding_gene nucleoside diphosphate kinase activity ; GO:0004550 | inferred from sequence or structural similarity with SGD:S000001550 CTP biosynthetic process ; GO:0006241 | inferred from electronic annotation with InterPro:IPR001564 UTP biosynthetic process ; GO:0006228 | inferred from electronic annotation with InterPro:IPR001564 GTP biosynthetic process ; GO:0006183 | inferred from electronic annotation with InterPro:IPR001564 nucleoside diphosphate phosphorylation ; GO:0006165 | inferred from sequence or structural similarity with SGD:S000001550 nucleoside triphosphate biosynthetic process ; GO:0009142 | inferred from sequence or structural similarity with SGD:S000001550 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000001550 "CG5310, nmdyn-D6" "IPR001564:Nucleoside diphosphate kinase, IPR023005:Nucleoside diphosphate kinase, active site" CG5310 11-Aug-17 DroID_v2017_08 "Drer\nme4, Drer\nme2b.1, Drer\nme6, Drer\nme7, Drer\nme5" Scer\YNK1 Cele\Y48G8AL.15 "Xtro\nme3, Xtro\nme5, Xtro\nme6, Xtro\nme7, Xtro\nme9, Xtro\nme4, Xtro\nme2" "Mmus\Nme7, Mmus\Nme5, Mmus\Nme4, Mmus\Nme8, Mmus\Nme3, Mmus\Nme1, Mmus\Nme2, Mmus\Nme6" "Hsap\NME5, Hsap\NME4, Hsap\NME7, Hsap\NME8, Hsap\NME3, Hsap\NME1, Hsap\NME2, Hsap\NME6" viable FBgn0259342 C170 - http://flybase.org/reports/FBgn0259342 gene - - - C170 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0260641 Hsf::nkd - http://flybase.org/reports/FBgn0260641 engineered_fusion_gene - - - Hsf::nkd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005372 x1 x1 http://flybase.org/reports/FBgn0005372 - gene - - - x1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267513 28SrRNA-Psi:CR45853 28S ribosomal RNA pseudogene:CR45853 http://flybase.org/reports/FBgn0267513 pseudogene_attribute - - - "28SrRNA-Psi:CR45853, CR45853" - CR45853 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037654 CG11983 - http://flybase.org/reports/FBgn0037654 protein_coding_gene - - - CG11983 - CG11983 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell DRSC14458 K 0.637871752 -0.263519958 -0.06034821 0.005325517 -1.525328795 0.521638063 FBgn0032913 CG9259 - http://flybase.org/reports/FBgn0032913 protein_coding_gene - - - CG9259 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG9259 11-Aug-17 DroID_v2017_08 - - "Cele\dhs-27, Cele\F56A4.5, Cele\F59B1.10, Cele\E02C12.8, Cele\T16G1.3, Cele\E02C12.6, Cele\C04F6.7, Cele\Y11D7A.8, Cele\nhr-246, Cele\H37A05.2, Cele\C29F7.2, Cele\F58B4.5, Cele\T16G1.6, Cele\H06H21.8, Cele\Y45G12C.4, Cele\F49C12.7, Cele\E02C12.9, Cele\C29F7.1, Cele\E02C12.10, Cele\F59B1.8, Cele\C18B10.6, Cele\F20D6.5" - - - viable FBgn0052358 tRNA:Leu-CAG-1-2 transfer RNA:Leucine-CAG 1-2 http://flybase.org/reports/FBgn0052358 tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "AE002602.trna10-LeuCAG, tRNA:L:CAG:AE002602-f, CR32358, chr3L.trna44-LeuCAG, tRNA-Leu-CAG-1-2, tRNA:Leu-CAG-1-2, tRNA:CR32358, CUG" - CR32358 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266680 CR45170 - http://flybase.org/reports/FBgn0266680 non_protein_coding_gene - - - CR45170 - CR45170 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003026 ovi ovioculus http://flybase.org/reports/FBgn0003026 - gene - - - ovi - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,viable,male,reduced" "egg,wing" FBgn0001131 gr gracile http://flybase.org/reports/FBgn0001131 - gene - - - gr - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male sterile,viable,poor" "wing,adult abdomen" FBgn0035692 Sf3b6 Splicing factor 3b subunit 6 http://flybase.org/reports/FBgn0035692 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN001765154" U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN001765154 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2 snRNP ; GO:0005686 | colocalizes_with inferred from direct assay U2-type spliceosomal complex ; GO:0005684 | inferred from biological aspect of ancestor with PANTHER:PTN001765154 "cg13298, CG13298, Sf3b6, SF3B6" "IPR000504:RNA recognition motif domain, IPR034150:SF3B14, RNA recognition motif" CG13298 11-Aug-17 DroID_v2017_08 Drer\sf3b6 Scer\IST3 Cele\C50D2.5 Xtro\sf3b6 Mmus\Sf3b6 Hsap\SF3B6 "visible,lethal,neuroanatomy defective,partially lethal - majority die" "wing,wing vein,ectopic,ganglion mother cell,mesothoracic tergum" DRSC09972 I 6.73025579 1.418457494 1.060828269 0.377725373 -1.187746024 -0.706984776 FBgn0035050 ST6Gal Sialyltransferase http://flybase.org/reports/FBgn0035050 protein_coding_gene "sialyltransferase activity ; GO:0008373 | inferred from direct assay beta-galactoside alpha-2,6-sialyltransferase activity ; GO:0003835 | inferred from direct assay" neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from biological aspect of ancestor with PANTHER:PTN000346035 oligosaccharide metabolic process ; GO:0009311 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "D.SiaT, CG4871, dSiaT, DmPST, ST6Gal, DSiaT, D.SialT, DmSialT, SialT, dST6Gal I" IPR001675:Glycosyl transferase family 29 CG4871 11-Aug-17 DroID_v2017_08 "Drer\st8sia6, Drer\st8sia1, Drer\st3gal2, Drer\st6galnac5b, Drer\st3gal5, Drer\st3gal1l2, Drer\st6galnac3, Drer\st3gal3a, Drer\st6gal2b, Drer\st3gal8, Drer\st3gal1l3, Drer\st8sia7.1, Drer\st8sia5, Drer\st6gal1, Drer\st6galnac1.1, Drer\st3gal7, Drer\st3gal1, Drer\st8sia2, Drer\st6galnac, Drer\st6galnac4, Drer\st8sia4, Drer\st6galnac1.2, Drer\st6galnac6, Drer\st6galnac5a, Drer\st3gal4, Drer\st3gal3b, Drer\st8sia3, Drer\st3gal1l, Drer\st8sia7.1p, Drer\LOC100334439, Drer\st6gal2a" - Cele\Y94H6A.10 "Xtro\st6galnac4, Xtro\st3gal2.1, Xtro\st3gal5, Xtro\st6galnac2, Xtro\st6gal2, Xtro\st3gal4, Xtro\st3gal1, Xtro\st8sia4, Xtro\st6galnac5, Xtro\st8sia6, Xtro\st3gal2.2, Xtro\st8sia2, Xtro\st6galnac6, Xtro\st8sia1, Xtro\st6galnac3, Xtro\st8sia3, Xtro\st3gal3, Xtro\st6gal1, Xtro\st3gal6" "Mmus\St6galnac6, Mmus\St8sia2, Mmus\St6gal2, Mmus\St6galnac2, Mmus\St3gal1, Mmus\St6galnac5, Mmus\St6galnac3, Mmus\St8sia1, Mmus\St8sia6, Mmus\St3gal2, Mmus\St3gal4, Mmus\St6galnac4, Mmus\St6galnac1, Mmus\St3gal6, Mmus\St3gal5, Mmus\St8sia5, Mmus\St3gal3, Mmus\St8sia3, Mmus\St8sia4, Mmus\St6gal1" "Hsap\ST3GAL3, Hsap\ST6GALNAC6, Hsap\ST6GALNAC2, Hsap\ST8SIA2, Hsap\ST3GAL6, Hsap\ST8SIA4, Hsap\ST8SIA6, Hsap\ST6GALNAC1, Hsap\ST3GAL1, Hsap\ST6GALNAC4, Hsap\ST6GALNAC3, Hsap\ST6GAL2, Hsap\ST3GAL2, Hsap\ST8SIA5, Hsap\ST6GALNAC5, Hsap\ST8SIA3, Hsap\ST6GAL1, Hsap\ST8SIA1, Hsap\ST3GAL5, Hsap\ST3GAL4" "viable,fertile,short lived,locomotor behavior defective,bang sensitive,paralytic,heat sensitive,neuroanatomy defective,neurophysiology defective,chemical resistant,recessive" "embryonic/larval neuromuscular junction,NMJ bouton" FBgn0015016 Bora-Bora Bora-Bora http://flybase.org/reports/FBgn0015016 - region - - - Bora-Bora - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263616 CR43625 - http://flybase.org/reports/FBgn0263616 non_protein_coding_gene - - - CR43625 - CR43625 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002144 l(2)K335 lethal (2) K335 http://flybase.org/reports/FBgn0002144 - gene - - - l(2)K335 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052672 Atg8a Autophagy-related 8a http://flybase.org/reports/FBgn0052672 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from physical interaction with Atg1 protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000000174 autophagy ; GO:0006914 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from genetic interaction with daw macroautophagy ; GO:0016236 | inferred from expression pattern regulation of protein ubiquitination ; GO:0031396 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype autolysosome ; GO:0044754 | inferred from direct assay autophagosome lumen ; GO:0034423 | inferred from direct assay autophagosome ; GO:0005776 | inferred from direct assay amphisome ; GO:0044753 | inferred from direct assay "Atg8a, ATG8a, CG32672, CG1534, BcDNA:LD05816, atg8, atg8a, ATG8, LC3, Atg8/LC3, DrAtg8a, Atg8A, Atg8, atg8A, LC3/Atg8, ATG8/LC3, DmAtg8a, dAtg8a" "IPR004241:Autophagy protein Atg8 ubiquitin-like, IPR029071:Ubiquitin-related domain" CG32672 11-Aug-17 DroID_v2017_08 "Drer\gabarapa, Drer\gabarapl2, Drer\map1lc3b, Drer\zgc:92606, Drer\map1lc3c, Drer\map1lc3a, Drer\map1lc3cl, Drer\gabarapb" Scer\ATG8 "Cele\lgg-3, Cele\lgg-1" "Xtro\map1lc3a, Xtro\gabarapl2, Xtro\gabarapl1, Xtro\map1lc3b, Xtro\map1lc3c" "Mmus\Gabarapl2, Mmus\Map1lc3b, Mmus\Gabarapl1, Mmus\Map1lc3a, Mmus\Gabarap" "Hsap\GABARAP, Hsap\MAP1LC3C, Hsap\MAP1LC3A, Hsap\MAP1LC3B2, Hsap\GABARAPL1, Hsap\GABARAPL2, Hsap\MAP1LC3B" "long lived,memory defective,recessive,short lived,male,melanotic mass phenotype,decreased cell death,viable" "embryonic/larval fat body,somatic clone | third instar larval stage,fat body,embryonic/larval salivary gland" FBgn0267780 CR46111 - http://flybase.org/reports/FBgn0267780 non_protein_coding_gene - - - CR46111 - CR46111 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263949 BG00767 - http://flybase.org/reports/FBgn0263949 gene - - - BG00767 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,starvation stress response defective,temperature response defective,gravitaxis defective,male limited" FBgn0029798 CG4078 - http://flybase.org/reports/FBgn0029798 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR010614 ATP-dependent DNA helicase activity ; GO:0004003 | inferred from sequence or structural similarity with UniProtKB:Q9NZ71 ATP binding ; GO:0005524 | inferred from sequence or structural similarity with UniProtKB:Q9NZ71 telomere maintenance ; GO:0000723 | inferred from electronic annotation with InterPro:IPR030845 DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR030845 regulation of double-strand break repair via homologous recombination ; GO:0010569 | inferred from sequence or structural similarity with UniProtKB:Q9NZ71 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q0VGM9 CG4078 "IPR006555:ATP-dependent helicase, C-terminal, IPR013020:DNA helicase (DNA repair), Rad3 type, IPR014013:Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, IPR030845:Regulator of telomere elongation helicase 1, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR010614:DEAD2, IPR006554:Helicase-like, DEXD box c2 type" CG4078 11-Aug-17 DroID_v2017_08 "Drer\rtel1, Drer\brip1" Scer\CHL1 "Cele\dog-1, Cele\rtel-1" Xtro\brip1 "Mmus\Rtel1, Mmus\Brip1" "Hsap\RTEL1, Hsap\LOC102725121, Hsap\BRIP1" "viable,visible" trichogen cell FBgn0259959 Sfp26Ac Seminal fluid protein 26Ac http://flybase.org/reports/FBgn0259959 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp26Ac, CG42469" - CG42469 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043492 bcd::ftz bcd::ftz http://flybase.org/reports/FBgn0043492 engineered_fusion_gene - - - bcd::ftz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031722 CG14011 - http://flybase.org/reports/FBgn0031722 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG14011 - CG14011 11-Aug-17 DroID_v2017_08 "Drer\LOC103909961, Drer\zgc:153293" - Cele\T12A2.3 - Mmus\Ccdc34 Hsap\CCDC34 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0005263 l(3)SG83 lethal (3) SG83 http://flybase.org/reports/FBgn0005263 - gene - - - l(3)SG83 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052971 CG32971 - http://flybase.org/reports/FBgn0052971 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from electronic annotation with InterPro:IPR009332 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR009332 mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000277332 CG32971 IPR009332:Mediator of RNA polymerase II transcription subunit 22 CG32971 11-Aug-17 DroID_v2017_08 Drer\med22 - Cele\mdt-22 Xtro\med22 Mmus\Med22 Hsap\MED22 viable FBgn0037853 CG14696 - http://flybase.org/reports/FBgn0037853 protein_coding_gene - - - CG14696 "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG14696 11-Aug-17 DroID_v2017_08 "Drer\zgc:110353, Drer\arrdc1b, Drer\arrdc1a, Drer\arrdc3b, Drer\arrdc3a, Drer\txnipa, Drer\LOC799768, Drer\arrdc2, Drer\zgc:110626, Drer\txnipb, Drer\si:ch211-130m23.2" "Scer\CSR2, Scer\RIM8, Scer\ROD1, Scer\ROG3, Scer\LDB19, Scer\ECM21, Scer\ALY1, Scer\ALY2, Scer\ART5" "Cele\arrd-11, Cele\arrd-15, Cele\arrd-3, Cele\arrd-27, Cele\arrd-12, Cele\arrd-22, Cele\arrd-24, Cele\arrd-1, Cele\arrd-5, Cele\arrd-2, Cele\arrd-14, Cele\arrd-13, Cele\rnh-1.2, Cele\arrd-18, Cele\arrd-6, Cele\arrd-25, Cele\arrd-8, Cele\arrd-16, Cele\arrd-7, Cele\arrd-4, Cele\arrd-19, Cele\arrd-23, Cele\arrd-9" "Xtro\txnip, Xtro\arrdc2, Xtro\arrdc3, Xtro\arrdc4" "Mmus\Arrdc4, Mmus\Arrdc2, Mmus\Arrdc5, Mmus\Txnip, Mmus\Arrdc3, Mmus\Arrdc1" "Hsap\ARRDC1, Hsap\ARRDC5, Hsap\ARRDC3, Hsap\TXNIP, Hsap\ARRDC4, Hsap\ARRDC2" viable FBgn0265039 CR44156 - http://flybase.org/reports/FBgn0265039 non_protein_coding_gene - - - CR44156 - CR44156 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261640 CR42723 - http://flybase.org/reports/FBgn0261640 pseudogene_attribute - - - CR42723 - CR42723 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001839 l(1)ts1082 lethal (1) ts1082 http://flybase.org/reports/FBgn0001839 - gene - - - l(1)ts1082 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0265986 CR44765 - http://flybase.org/reports/FBgn0265986 non_protein_coding_gene - - - CR44765 - CR44765 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044072 E(rst)J76 E(rst)J76 http://flybase.org/reports/FBgn0044072 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "J76, E(rst)J76" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069988 BG02063 BG02063 http://flybase.org/reports/FBgn0069988 gene - - - BG02063 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0011365 l(3)j4B9 lethal (3) j4B9 http://flybase.org/reports/FBgn0011365 - gene - - - l(3)j4B9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030844 ppk23 pickpocket 23 http://flybase.org/reports/FBgn0030844 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 male courtship behavior ; GO:0008049 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype response to pheromone ; GO:0019236 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK23, CG8527, ppk23, Ppk23" IPR001873:Epithelial sodium channel CG8527 11-Aug-17 DroID_v2017_08 "Drer\asic1a, Drer\asic1b, Drer\asic1c, Drer\asic4b, Drer\asic2, Drer\asic4a" - "Cele\del-7, Cele\acd-1, Cele\acd-3, Cele\flr-1, Cele\delm-1, Cele\acd-2, Cele\acd-5, Cele\acd-4, Cele\delm-2" "Xtro\asic5, Xtro\scnn1b, Xtro\scnn1g, Xtro\asic1, Xtro\asic4, Xtro\scnn1d, Xtro\scnn1a" "Mmus\Asic4, Mmus\Scnn1g, Mmus\Asic2, Mmus\Asic1, Mmus\Asic5, Mmus\Asic3, Mmus\Scnn1a, Mmus\Scnn1b" "Hsap\SCNN1B, Hsap\SCNN1D, Hsap\ASIC1, Hsap\ASIC3, Hsap\SCNN1G, Hsap\ASIC5, Hsap\ASIC4, Hsap\ASIC2, Hsap\SCNN1A" "courtship behavior defective,male,behavior defective,recessive,mating behavior defective,viable,fertile" FBgn0052496 CR32496 - http://flybase.org/reports/FBgn0052496 pseudogene_attribute - - - "CG32496, CR32496, FBpp0074273" - CR32496 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036075 CG8065 - http://flybase.org/reports/FBgn0036075 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8065 IPR031883:Protein of unknown function DUF4763 CG8065 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027373 RevIII-7b RevIII-7b http://flybase.org/reports/FBgn0027373 - gene - - - RevIII-7b - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266227 CR44922 - http://flybase.org/reports/FBgn0266227 non_protein_coding_gene - - - "CR44922, lincRNA.670" - CR44922 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263239 dar1 dendritic arbor reduction 1 http://flybase.org/reports/FBgn0263239 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with MGI:MGI:1338056 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:1338056 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype positive regulation of dendrite extension ; GO:1903861 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Dar1, CG12029, dar1, l(3)SH5, l(3)63Ed" "IPR013087:Zinc finger C2H2-type, IPR011990:Tetratricopeptide-like helical domain" CG12029 11-Aug-17 DroID_v2017_08 "Drer\klf13, Drer\klf17, Drer\klf1, Drer\klf5a, Drer\klf11a, Drer\klf2a, Drer\klf7a, Drer\klf11b, Drer\klf6a, Drer\sp5l, Drer\klf7b, Drer\sp3b, Drer\sp1, Drer\klf2b, Drer\zgc:153115, Drer\klf5b, Drer\klf8, Drer\klf4, Drer\klf9, Drer\klf5l, Drer\klf12b, Drer\klf12a, Drer\klf6b, Drer\sp3a" "Scer\FZF1, Scer\AZF1, Scer\COM2, Scer\CRZ1, Scer\SWI5, Scer\ACE2" "Cele\sptf-2, Cele\klf-3, Cele\klf-1, Cele\hbl-1, Cele\klf-2" "Xtro\klf4, Xtro\klf7, Xtro\klf2, Xtro\klf3, Xtro\znf534, Xtro\klf11, Xtro\klf13, Xtro\klf9, Xtro\klf8, Xtro\sp1, Xtro\klf12, Xtro\klf5, Xtro\klf10, Xtro\klf17, Xtro\sp5" "Mmus\Klf16, Mmus\Klf9, Mmus\Klf14, Mmus\Klf6, Mmus\Klf8, Mmus\Klf10, Mmus\Klf7, Mmus\Sp5, Mmus\Klf1, Mmus\Klf13, Mmus\Klf4, Mmus\Klf2, Mmus\Klf3, Mmus\Sp3, Mmus\Klf12, Mmus\Klf11, Mmus\Klf5, Mmus\Sp1" "Hsap\KLF1, Hsap\KLF16, Hsap\KLF2, Hsap\SP5, Hsap\KLF10, Hsap\SP1, Hsap\ZNF316, Hsap\KLF14, Hsap\KLF4, Hsap\SP3, Hsap\ZNF853, Hsap\KLF9, Hsap\KLF3, Hsap\KLF7, Hsap\KLF13, Hsap\KLF6, Hsap\KLF5, Hsap\KLF8, Hsap\KLF12" FBgn0039303 CG11857 - http://flybase.org/reports/FBgn0039303 protein_coding_gene - "retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000078466" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004932 CG11857 "IPR004932:Retrieval of early ER protein Rer1, IPR020846:Major facilitator superfamily domain" CG11857 11-Aug-17 DroID_v2017_08 Drer\rer1 Scer\RER1 Cele\rer-1 Xtro\rer1 Mmus\Rer1 Hsap\RER1 viable DRSC14411 E 0.044100295 0.33729703 2.119432512 -0.146064842 0.015953727 0.090314885 FBgn0260742 CG12213 - http://flybase.org/reports/FBgn0260742 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG12213, 87A7-9/3, anon-87Ab" - CG12213 11-Aug-17 DroID_v2017_08 Drer\golim4b - - - Mmus\Rnf214 Hsap\RNF214 FBgn0262898 CR43253 - http://flybase.org/reports/FBgn0262898 non_protein_coding_gene - - - "CG43253, CR43253, lincRNA.596" - CR43253 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035023 ITP Ion transport peptide http://flybase.org/reports/FBgn0035023 protein_coding_gene "neuropeptide hormone activity ; GO:0005184 | inferred from electronic annotation with InterPro:IPR001166, InterPro:IPR018251 hormone activity ; GO:0005179 | non-traceable author statement neuropeptide hormone activity ; GO:0005184 | non-traceable author statement" circadian sleep/wake cycle ; GO:0042745 | inferred from genetic interaction with Pdf neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement locomotor rhythm ; GO:0045475 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from expression pattern "extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR001166, InterPro:IPR018251 extracellular space ; GO:0005615 | inferred from sequence model" "CG13586, CHH-like, BcDNA:SD05282, chgh, ITP, DrmITP, DrmITPL1, DrmITPL2, itp, Drm-ITP, Itp" "IPR018251:Crustacean neurohormone, conserved site, IPR001166:Arthropod neurohormone, IPR031098:Arthropod neurohormone/Alpha-latrotoxin associated low molecular weight protein" CG13586 11-Aug-17 DroID_v2017_08 - - "Cele\C05E11.6, Cele\ZC168.2" - - - "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0267246 CR45686 - http://flybase.org/reports/FBgn0267246 non_protein_coding_gene - - - CR45686 - CR45686 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065435 l(2)SH1473 lethal (2) SH1473 http://flybase.org/reports/FBgn0065435 gene - - - "l(2)SH1473, l(2)SH2 1473" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051814 CG31814 - http://flybase.org/reports/FBgn0051814 protein_coding_gene - - integral component of plasma membrane ; GO:0005887 | inferred from sequence model "BG:DS08249.1, CG31814, 31814" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG31814 11-Aug-17 DroID_v2017_08 "Drer\zgc:172120, Drer\cxcr3.1, Drer\f11r.2, Drer\jam3b, Drer\jam2b, Drer\igsf11, Drer\LOC100151468, Drer\negr1, Drer\si:zfos-1011f11.1, Drer\si:dkey-65b12.12, Drer\lsamp, Drer\vsig8a, Drer\zgc:153911, Drer\ntm, Drer\LOC797620, Drer\jam2a, Drer\zgc:162154, Drer\si:dkey-250k15.10, Drer\zgc:123297, Drer\jam3a, Drer\sc:d0835, Drer\zgc:153073, Drer\si:ch211-9d9.7, Drer\esama, Drer\cxadr, Drer\si:ch211-215e19.3, Drer\zgc:110372, Drer\mxra8b, Drer\vsig8b, Drer\f11r.1, Drer\mxra8a, Drer\opcml, Drer\gpa33, Drer\pigrl4.2, Drer\esamb" - Cele\rig-5 "Xtro\cd276, Xtro\negr1, Xtro\lsamp, Xtro\btn2a2, Xtro\vtcn1, Xtro\ntm" "Mmus\Btnl10, Mmus\Skint1, Mmus\Vtcn1, Mmus\Skint8, Mmus\Igsf5, Mmus\Negr1, Mmus\Cxadr, Mmus\Igsf11, Mmus\Mxra8, Mmus\Esam, Mmus\Iglon5, Mmus\Btnl9, Mmus\Btn2a2, Mmus\Gm1123, Mmus\Skint4, Mmus\Jam3, Mmus\F11r, Mmus\Gpa33, Mmus\Vsig1, Mmus\Skint2, Mmus\Ermap, Mmus\Jam2, Mmus\Pdcd1lg2, Mmus\Vsir, Mmus\Btnl2, Mmus\Clmp, Mmus\Ntm, Mmus\Vsig2, Mmus\Hepacam2, Mmus\Lsamp, Mmus\Opcml, Mmus\Vsig8, Mmus\Skint3, Mmus\Cd276, Mmus\Btn1a1" "Hsap\BTNL2, Hsap\BTN2A2, Hsap\MXRA8, Hsap\BTNL3, Hsap\C10orf54, Hsap\BTNL8, Hsap\F11R, Hsap\VSIG8, Hsap\CXADR, Hsap\CLMP, Hsap\ESAM, Hsap\BTN1A1, Hsap\VSIG2, Hsap\VSIG1, Hsap\LOC102723996, Hsap\VTCN1, Hsap\JAM3, Hsap\OPCML, Hsap\NTM, Hsap\BTN3A1, Hsap\BTN3A3, Hsap\JAM2, Hsap\BTNL9, Hsap\C1orf204, Hsap\LSAMP, Hsap\IGSF11, Hsap\CD276, Hsap\GPA33, Hsap\IGSF5, Hsap\IGLON5, Hsap\BTN3A2, Hsap\CD80, Hsap\ERMAP, Hsap\NEGR1" DRSC01336 IE -2.922077319 -3.235320525 -2.025887636 1.589330465 -0.457304138 1.153801896 FBgn0038460 CG18622 - http://flybase.org/reports/FBgn0038460 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RH18149, CG18622" - CG18622 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027791 O-fut2 O-fucosyltransferase 2 http://flybase.org/reports/FBgn0027791 - protein_coding_gene peptide-O-fucosyltransferase activity ; GO:0046922 | traceable author statement peptide-O-fucosyltransferase activity ; GO:0046922 | inferred from direct assay "embryo development ; GO:0009790 | non-traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement O-glycan processing ; GO:0016266 | traceable author statement O-glycan processing ; GO:0016266 | inferred from direct assay" endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "O-FUT2, CG14789, EG:BACN32G11.6, O-fut2, O-fut, Ofut2, OFut2" IPR019378:GDP-fucose protein O-fucosyltransferase CG14789 11-Aug-17 DroID_v2017_08 Drer\pofut2 - Cele\pad-2 Xtro\pofut2 Mmus\Pofut2 Hsap\POFUT2 "viable,fertile" FBgn0031068 Alr Augmenter of liver regeneration http://flybase.org/reports/FBgn0031068 protein_coding_gene protein disulfide oxidoreductase activity ; GO:0015035 | inferred from biological aspect of ancestor with PANTHER:PTN000291228 flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from biological aspect of ancestor with PANTHER:PTN000291228 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000291228 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR017905 regulation of cell cycle ; GO:0051726 | inferred from direct assay tissue regeneration ; GO:0042246 | inferred from expression pattern inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000291228 "alr, Alr, CG12534" IPR017905:ERV/ALR sulfhydryl oxidase domain CG12534 11-Aug-17 DroID_v2017_08 Drer\gfer "Scer\ERV2, Scer\ERV1" Cele\F56C11.3 Xtro\gfer Mmus\Gfer Hsap\GFER "lethal - all die before end of larval stage,recessive,some die during third instar larval stage" imaginal disc FBgn0266622 CR45129 - http://flybase.org/reports/FBgn0266622 non_protein_coding_gene - - - CR45129 - CR45129 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002455 mcd microdiscs http://flybase.org/reports/FBgn0002455 FBgn0004707 gene - - - "l(3)1602, l(3)ds11, l(3)SG8, mcd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,eye-antennal disc,ventral thoracic disc,haltere disc,genital disc" FBgn0005367 Vc Vortice http://flybase.org/reports/FBgn0005367 - gene - - - Vc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050421 Usp15-31 Ubiquitin specific protease 15/31 http://flybase.org/reports/FBgn0050421 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:20060 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:20060 cellular_component ; GO:0005575 | no biological data available "CG30421, CG9189, CG3872, Usp15-31, Usp15, Usp31, USP43, Q9W117" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG30421 11-Aug-17 DroID_v2017_08 "Drer\usp33, Drer\usp43b, Drer\usp32, Drer\usp31, Drer\usp11, Drer\usp43a, Drer\usp4, Drer\usp20, Drer\usp19" Scer\UBP12 - "Xtro\usp15, Xtro\usp4, Xtro\usp32, Xtro\usp19, Xtro\usp31, Xtro\usp20, Xtro\usp33" "Mmus\Usp4, Mmus\Usp19, Mmus\Usp20, Mmus\Usp15, Mmus\Usp31, Mmus\Usp33, Mmus\Usp11, Mmus\Usp43, Mmus\Usp32" "Hsap\USP15, Hsap\USP32, Hsap\USP31, Hsap\USP43, Hsap\USP20, Hsap\USP4, Hsap\USP6, Hsap\USP11, Hsap\USP19" "viable,locomotor behavior defective" FBgn0001196 His2A Histone H2A http://flybase.org/reports/FBgn0001196 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002119, InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072" larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype chromosome ; GO:0005694 | inferred from direct assay nucleosome ; GO:0000786 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR002119 "H2A, HisC, H2A1, H2a, H2A.1, His2a, DmeH2a, H2[[A]], His2A, histone, his, hist, dH2A, dH2a" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , egg stage | fertilized egg " " spermatozoon

, spermatid | early

, male pronucleus

, spermatid | late

, female pronucleus

" lethal embryonic/larval somatic muscle FBgn0035795 CG16998 - http://flybase.org/reports/FBgn0035795 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP104, CG16998" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG16998 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-78l4.10, Drer\LOC558805, Drer\si:dkey-21e2.13, Drer\si:dkey-78l4.4, Drer\si:ch211-165b19.9" - Cele\try-1 "Xtro\cfd, Xtro\prtn3, Xtro\gzmh, Xtro\gzma" "Mmus\Gzmm, Mmus\Prss57" "Hsap\CMA1, Hsap\PRSS57, Hsap\GZMM" viable FBgn0039733 CG11504 - http://flybase.org/reports/FBgn0039733 protein_coding_gene - - - CG11504 IPR006578:MADF domain CG11504 11-Aug-17 DroID_v2017_08 "Drer\zgc:152938, Drer\LOC100330838, Drer\si:ch211-207i20.3" - "Cele\madf-5, Cele\madf-8, Cele\madf-2, Cele\madf-4, Cele\madf-10, Cele\madf-9, Cele\madf-3" - - - viable FBgn0060637 l(3)S084308b lethal (3) S084308b http://flybase.org/reports/FBgn0060637 gene - - - "0843/08, l(3)S084308b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266043 CR44808 - http://flybase.org/reports/FBgn0266043 non_protein_coding_gene - - - CR44808 - CR44808 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262027 CR42838 - http://flybase.org/reports/FBgn0262027 pseudogene_attribute - - - CR42838 - CR42838 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002508 l(3)SG69 lethal (3) SG69 http://flybase.org/reports/FBgn0002508 - gene - - - l(3)SG69 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003393 shl shorter legs http://flybase.org/reports/FBgn0003393 - gene - - - shl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male fertile,reduced,viable,male" leg FBgn0039357 CG4743 - http://flybase.org/reports/FBgn0039357 protein_coding_gene S-adenosyl-L-methionine transmembrane transporter activity ; GO:0000095 | inferred from sequence or structural similarity with UniProtKB:Q70HW3 S-adenosyl-L-methionine transmembrane transporter activity ; GO:0000095 | inferred from biological aspect of ancestor with PANTHER:PTN000756630 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 S-adenosyl-L-methionine transport ; GO:0015805 | inferred from sequence or structural similarity with UniProtKB:Q70HW3 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q70HW3 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN002377827 CG4743 "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG4743 11-Aug-17 DroID_v2017_08 Drer\slc25a26 "Scer\PET8, Scer\MME1" "Cele\slc-25A26, Cele\F55G1.5" Xtro\slc25a26 Mmus\Slc25a26 Hsap\SLC25A26 "viable,fertile" DRSC15636 K 0.281880371 -0.23979025 -0.289919907 -0.325801128 -1.988401405 -0.81444552 FBgn0002423 l(3)F19 lethal (3) F19 http://flybase.org/reports/FBgn0002423 - gene - - - "l(3)19, l(3)F19" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259725 CG42379 - http://flybase.org/reports/FBgn0259725 protein_coding_gene - - - "CG42379, Dromel_CG9865_FBtr0071680_uorf2, CG9865(uORF2)" - CG42379 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039244 CG11069 - http://flybase.org/reports/FBgn0039244 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 CG11069 "IPR003439:ABC transporter-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG11069 11-Aug-17 DroID_v2017_08 "Drer\abcg8, Drer\abcg4a, Drer\abcg5, Drer\abcg4b, Drer\abcg2b, Drer\abcg2a, Drer\abcg1" "Scer\PDR12, Scer\ADP1, Scer\PDR11, Scer\ARB1, Scer\AUS1, Scer\PDR10, Scer\YOL075C" "Cele\wht-6, Cele\abch-1, Cele\wht-2" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg8, Mmus\Abcg5, Mmus\Abcg4, Mmus\Abcg3, Mmus\Abcg1, Mmus\Abcg2" "Hsap\ABCG4, Hsap\ABCG1, Hsap\ABCG8, Hsap\ABCG5" FBgn0267501 18SrRNA:CR45841 18S ribosomal RNA:CR45841 http://flybase.org/reports/FBgn0267501 rRNA_gene - - - "18SrRNA:CR45841, CR45841" - CR45841 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039270 PQBP1 Poly-glutamine tract binding protein 1 http://flybase.org/reports/FBgn0039270 protein_coding_gene - "microvillus organization ; GO:0032528 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 positive regulation of translation ; GO:0045727 | inferred from direct assay" rough endoplasmic reticulum ; GO:0005791 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "PQBP1, dPQBP1, CG11820, PQBP-1, dPQBP-1" IPR001202:WW domain CG11820 11-Aug-17 DroID_v2017_08 Drer\pqbp1 - "Cele\pqbp-1.2, Cele\pqbp-1.1" - "Mmus\Pqbp1, Mmus\Leo1" Hsap\PQBP1 "viable,fertile,short lived,semidominant,learning defective" DRSC14393 K -1.180289559 -0.355972979 -0.891118449 0.475330872 3.004068797 0.371146393 FBgn0267561 CR45901 - http://flybase.org/reports/FBgn0267561 non_protein_coding_gene - - - CR45901 - CR45901 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053733 snmRNA:430:CR33733 snmRNA:430:CR33733 http://flybase.org/reports/FBgn0053733 non_protein_coding_gene - - - "CR33733, snmRNA:430:CR33733" - CR33733 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060551 l(3)S098202b lethal (3) S098202b http://flybase.org/reports/FBgn0060551 gene - - - "0982/02, l(3)S098202b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0085317 CG34288 - http://flybase.org/reports/FBgn0085317 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34288 - CG34288 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022305 l(1)L35.1 lethal (1) L35.1 http://flybase.org/reports/FBgn0022305 - gene - - - "L35.1, l(1)L35.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034761 CG4250 - http://flybase.org/reports/FBgn0034761 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT13934, BcDNA:RH52355, CG4250" IPR006629:LPS-induced tumour necrosis factor alpha factor CG4250 11-Aug-17 DroID_v2017_08 "Drer\litaf, Drer\si:dkeyp-75b4.8, Drer\si:ch211-202h22.8, Drer\cdip1, Drer\si:ch211-202h22.9, Drer\si:ch211-202h22.7, Drer\si:ch211-157c3.4" - "Cele\Y87G2A.19, Cele\B0348.2, Cele\F36G3.3, Cele\Y40H7A.11, Cele\Y87G2A.18, Cele\Y37D8A.6, Cele\Y22D7AL.15, Cele\Y37D8A.26, Cele\F16F9.1, Cele\C08E8.1, Cele\Y37D8A.8, Cele\B0348.1" Xtro\litaf "Mmus\Cdip1, Mmus\Litaf" "Hsap\LITAF, Hsap\CDIP1" viable DRSC04455 K 0.909645007 0.028037528 0.751082044 0.047464076 2.021868905 1.167696855 FBgn0000034 AcpK Accessory gland protein K http://flybase.org/reports/FBgn0000034 - gene - - - AcpK - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0259307 EP-179 - http://flybase.org/reports/FBgn0259307 gene - - - EP-179 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing,chaeta" FBgn0052074 CG32074 - http://flybase.org/reports/FBgn0052074 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32074 - CG32074 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" DRSC22246 E 0.166899979 -0.004013923 1.536377871 0.445635472 -0.428984842 -1.022940209 FBgn0063643 CE3-3 CE3-3 http://flybase.org/reports/FBgn0063643 gene - - - CE3-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014977 l(1)BP l(1)Brand and Perrimon http://flybase.org/reports/FBgn0014977 - gene - - - l(1)BP - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020336 anon-65Bb anon-65Bb http://flybase.org/reports/FBgn0020336 - gene - - - "y, anon-65Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266834 CR45296 - http://flybase.org/reports/FBgn0266834 non_protein_coding_gene - - - CR45296 - CR45296 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035593 CG4603 - http://flybase.org/reports/FBgn0035593 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:25035 protein deubiquitination ; GO:0016579 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:25035 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 "CG4603, dYOD1, Q9VRJ9" "IPR003323:OTU domain, IPR029071:Ubiquitin-related domain" CG4603 11-Aug-17 DroID_v2017_08 Drer\yod1 Scer\OTU1 - Xtro\yod1 Mmus\Yod1 Hsap\YOD1 "viable,fertile,locomotor behavior defective" FBgn0036992 CG11796 - http://flybase.org/reports/FBgn0036992 protein_coding_gene 4-hydroxyphenylpyruvate dioxygenase activity ; GO:0003868 | inferred from biological aspect of ancestor with PANTHER:PTN000238554 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005956 tyrosine catabolic process ; GO:0006572 | inferred from biological aspect of ancestor with PANTHER:PTN000238554 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN002279033 Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN002279033 CG11796 "IPR004360:Glyoxalase/fosfomycin resistance/dioxygenase domain, IPR005956:4-hydroxyphenylpyruvate dioxygenase, IPR029068:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase" CG11796 11-Aug-17 DroID_v2017_08 "Drer\hip1, Drer\hpda, Drer\hpdb, Drer\hip1rb, Drer\hip1r" - "Cele\C31H2.4, Cele\Y18D10A.22, Cele\hpd-1" "Xtro\hip1r, Xtro\hpd, Xtro\hip1, Xtro\hpdl, Xtro\hpd" "Mmus\Hpd, Mmus\Hpdl, Mmus\Hip1r, Mmus\Hip1" "Hsap\HIP1R, Hsap\HIP1, Hsap\HPDL, Hsap\HPD" viable FBgn0015602 BEAF-32 Boundary element-associated factor of 32kD http://flybase.org/reports/FBgn0015602 FBgn0013752 protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with dwg regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay chromatin organization ; GO:0006325 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype histone H3-K9 methylation ; GO:0051567 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "BEAF-32, Beaf-32, BEAF32B, BEAF32A, BEAF32, BEAF-32A, BEAF, CG10159, BEAF-32B, bs04c01.y1, beaf, BEAF32b, Beaf32" "IPR003656:Zinc finger, BED-type, IPR004210:BESS motif, IPR013087:Zinc finger C2H2-type" CG10159 11-Aug-17 DroID_v2017_08 - - - - - - "visible,increased cell death,viable,fertile,lethal,partially,enhancer of variegation,suppressor of variegation,poor,male fertile,female sterile,recessive,maternal effect,dominant,developmental rate defective,large body,lethal - all die before end of larval stage,some die during third instar larval stage" "ommatidium,interommatidial bristle,rhabdomereGMR.PS,eye disc,eye,polytene chromosome | third instar larval stageAB1,polytene chromosome | third instar larval stage34B,X chromosome | male,egg chamber,nurse cell,supernumerary,embryonic/larval fat body,polytene chromosome,imaginal disc,embryonic/larval central nervous system" FBgn0028211 l(3)S011001c lethal (3) S011001c http://flybase.org/reports/FBgn0028211 gene - - - "0110/01, l(3)S011001, l(3)S011001c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039195 CG17782 - http://flybase.org/reports/FBgn0039195 protein_coding_gene - - - CG17782 IPR006631:Protein of unknown function DM4/12 CG17782 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0023513 CG14803 - http://flybase.org/reports/FBgn0023513 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available replication fork processing ; GO:0031297 | inferred from sequence or structural similarity with HGNC:21475 double-strand break repair via homologous recombination ; GO:0000724 | inferred from sequence or structural similarity with HGNC:21475 nuclear replication fork ; GO:0043596 | inferred from sequence or structural similarity with HGNC:21475 "EG:63B12.9, CG14803" "IPR016024:Armadillo-type fold, IPR029424:MMS22-like, C-terminal, IPR029425:Protein MMS22-like, N-terminal" CG14803 11-Aug-17 DroID_v2017_08 Drer\mms22l - Cele\fbxa-190 Xtro\mms22l Mmus\Mms22l Hsap\MMS22L viable FBgn0267898 CR46186 - http://flybase.org/reports/FBgn0267898 pseudogene_attribute - - - CR46186 - CR46186 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263233 robls54B roadblock similar 54B http://flybase.org/reports/FBgn0263233 protein_coding_gene dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 "CG34192, HDC06929, gene 3, GENE 3, robls54B" IPR004942:Roadblock/LAMTOR2 domain CG34192 11-Aug-17 DroID_v2017_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb1, Mmus\Dynlrb2" "Hsap\DYNLRB1, Hsap\DYNLRB2" FBgn0028147 l(3)S045230 lethal (3) S045230 http://flybase.org/reports/FBgn0028147 gene - - - "0452/30, l(3)S045230" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011616 l(1)I33f3-2 lethal (1) I33f3-2 http://flybase.org/reports/FBgn0011616 FBgn0010206 gene - - - "l(1)33f3, l(1)I33f3-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266971 CR45422 - http://flybase.org/reports/FBgn0266971 non_protein_coding_gene - - - CR45422 - CR45422 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016992 ms(3)1199A ms(3)1199A http://flybase.org/reports/FBgn0016992 - gene - - - ms(3)1199A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264006 dysc dyschronic http://flybase.org/reports/FBgn0264006 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of light stimulus ; GO:0050953 | inferred from electronic annotation with InterPro:IPR033028 sensory perception of sound ; GO:0007605 | inferred from electronic annotation with InterPro:IPR033028 regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys positive regulation of ion transmembrane transporter activity ; GO:0032414 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype synapse ; GO:0045202 | inferred from direct assay "CG34400, CG32132, CG17368, CG8760, anon-AE003536.1, CG32131, Dm_3L:69335, dysc, CG43749" "IPR033028:Whirlin, IPR001478:PDZ domain" CG43749 11-Aug-17 DroID_v2017_08 "Drer\pard3bb, Drer\pdzd7a, Drer\il16, Drer\grip2b, Drer\grid2ipa, Drer\dfnb31a, Drer\si:dkey-92i15.4, Drer\lnx1, Drer\slc9a3r1, Drer\dfnb31b, Drer\dlg5a, Drer\inadl, Drer\pdzd7b, Drer\grip1" - "Cele\dlg-1, Cele\ZK849.1" "Xtro\grip1, Xtro\dlg5, Xtro\dfnb31, Xtro\grid2ip, Xtro\pdzd7, Xtro\grip2, Xtro\lnx1" "Mmus\Patj, Mmus\Dlg5, Mmus\Grip1, Mmus\Mpdz, Mmus\Whrn, Mmus\Grasp, Mmus\Grid2ip, Mmus\Pdzd7, Mmus\Pdzd11, Mmus\Pdzd2, Mmus\Ush1c, Mmus\Lnx1, Mmus\Pdzph1, Mmus\Il16, Mmus\Grip2" "Hsap\WHRN, Hsap\IL16, Hsap\GRIP1, Hsap\PARD3B, Hsap\PDZD2, Hsap\FRMPD2, Hsap\GRASP, Hsap\DLG5, Hsap\MPDZ, Hsap\USH1C, Hsap\PDZD7, Hsap\PATJ, Hsap\LNX1, Hsap\GRID2IP" FBgn0003543 stu small tumoroid http://flybase.org/reports/FBgn0003543 - gene - - - stu - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,poor,male fertile,visible,melanotic mass phenotype" melanotic mass FBgn0260760 CG42558 - http://flybase.org/reports/FBgn0260760 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7866, CG42558" - CG42558 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034650 NC2alpha Negative Cofactor 2alpha http://flybase.org/reports/FBgn0034650 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription factor binding ; GO:0008134 | inferred from physical interaction with NC2β protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VJQ5 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from physical interaction with NC2β" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" nucleus ; GO:0005634 | inferred by curator from GO:0001075 "dDrap1, Drap1, dDrap1/dNC2a, dDrap, dNC2, CG10318, NC2alpha, NC2, Nc2alpha" "IPR003958:Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072:Histone-fold" CG10318 11-Aug-17 DroID_v2017_08 "Drer\LOC100535468, Drer\drap1" Scer\BUR6 Cele\drap-1 Xtro\drap1 Mmus\Drap1 Hsap\DRAP1 "viable,visible" mesothoracic tergum FBgn0050471 CG30471 - http://flybase.org/reports/FBgn0050471 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - "CG8185, CG30471" "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG30471 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-7, Cele\oac-53, Cele\oac-32, Cele\oac-31, Cele\oac-46, Cele\oac-20, Cele\oac-9, Cele\oac-54, Cele\oac-6, Cele\oac-55, Cele\oac-14, Cele\ndg-4, Cele\oac-50, Cele\oac-39, Cele\nrf-6, Cele\oac-5, Cele\oac-3, Cele\rhy-1" - Mmus\Oacyl - viable FBgn0260606 2L1540 - http://flybase.org/reports/FBgn0260606 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1540 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0263022 CG43317 - http://flybase.org/reports/FBgn0263022 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43317, CG14876" - CG43317 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036997 CG5955 - http://flybase.org/reports/FBgn0036997 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001509 coenzyme binding ; GO:0050662 | inferred from electronic annotation with InterPro:IPR001509 - - CG5955 "IPR001509:NAD-dependent epimerase/dehydratase, IPR016040:NAD(P)-binding domain" CG5955 11-Aug-17 DroID_v2017_08 "Drer\tdh, Drer\tdh2" - Cele\F08F3.4 Xtro\LOC101730350 Mmus\Tdh Hsap\TGDS "viable,body color defective" mesothoracic tergum FBgn0019687 l(3)LG12 lethal (3) LG12 http://flybase.org/reports/FBgn0019687 - gene - - - l(3)LG12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030749 AnxB11 Annexin B11 http://flybase.org/reports/FBgn0030749 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001464, InterPro:IPR018252, InterPro:IPR018502 actin binding ; GO:0003779 | inferred from sequence or structural similarity calcium-dependent phospholipid binding ; GO:0005544 | inferred from sequence or structural similarity with AnxB10" cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Anxb11, CG9968, BcDNA:GH16395, AnxB11, annexin, ANXB11" "IPR001464:Annexin, IPR018252:Annexin repeat, conserved site, IPR018502:Annexin repeat" CG9968 11-Aug-17 DroID_v2017_08 "Drer\anxa4, Drer\anxa1a, Drer\anxa3a, Drer\anxa3b, Drer\anxa5a, Drer\anxa11b, Drer\LOC103908630, Drer\anxa11a, Drer\anxa13l, Drer\zgc:110283, Drer\anxa6, Drer\anxa2a, Drer\anxa5b, Drer\prnprs3, Drer\anxa13, Drer\anxa1b, Drer\zgc:101785, Drer\anxa1c, Drer\anxa2b" - "Cele\nex-4, Cele\nex-2, Cele\nex-1, Cele\nex-3" "Xtro\anxa1, Xtro\anxa7, Xtro\anxa6, Xtro\anxa8, Xtro\anxa13, Xtro\anxa2, Xtro\anxa4, Xtro\anxa11, Xtro\anxa5, Xtro\anxa3" "Mmus\Anxa8, Mmus\Anxa1, Mmus\Anxa10, Mmus\Anxa9, Mmus\Anxa11, Mmus\Anxa3, Mmus\Anxa4, Mmus\Anxa7, Mmus\Anxa6, Mmus\Anxa2, Mmus\Anxa5" "Hsap\ANXA2, Hsap\ANXA4, Hsap\ANXA13, Hsap\ANXA6, Hsap\ANXA7, Hsap\ANXA3, Hsap\ANXA11, Hsap\ANXA9, Hsap\ANXA1, Hsap\ANXA8, Hsap\ANXA8L1, Hsap\ANXA10, Hsap\ANXA5" "lethal,viable" FBgn0001382 l(1)2Bn lethal (1) 2Bn http://flybase.org/reports/FBgn0001382 - gene - - - l(1)2Bn - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0031837 DIP-iota Dpr-interacting protein iota http://flybase.org/reports/FBgn0031837 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CT31597, CG11320, 11320, DIP-iota" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG11320 11-Aug-17 DroID_v2017_08 "Drer\vsig8a, Drer\kirrel3a, Drer\lrit3a, Drer\esama, Drer\zgc:110372, Drer\lrit1a, Drer\cxadr, Drer\zgc:153073, Drer\sdk1b, Drer\gpa33, Drer\pigrl4.2, Drer\cxcr3.1, Drer\igsf11, Drer\jam3a, Drer\ush2a, Drer\kirrelb, Drer\vsig8b, Drer\jam3b, Drer\kirrela, Drer\lsamp, Drer\esamb, Drer\jam2a, Drer\LOC100151468, Drer\si:dkey-250k15.10, Drer\ncam1b, Drer\f11r.1, Drer\f11r.2, Drer\mxra8b, Drer\paplna, Drer\lrit1b, Drer\si:ch1073-459j12.1, Drer\LOC565947, Drer\dscama, Drer\si:dkey-65b12.12, Drer\si:zfos-1011f11.1, Drer\kirrel3b, Drer\sdk1a, Drer\igsf9bb, Drer\si:ch211-215e19.3, Drer\igsf9a, Drer\itgb4, Drer\negr1, Drer\mxra8a, Drer\opcml, Drer\kirrel3l, Drer\jam2b, Drer\si:ch211-9d9.7, Drer\ntm, Drer\lrit3b" - "Cele\rig-5, Cele\igcm-1, Cele\zig-5" "Xtro\lsamp, Xtro\pecam1, Xtro\papln, Xtro\fcrl3, Xtro\negr1, Xtro\kirrel2, Xtro\ntm, Xtro\igsf9b, Xtro\lrit3, Xtro\LOC100486104" "Mmus\Gpa33, Mmus\Negr1, Mmus\Lrit1, Mmus\Hepacam2, Mmus\Ptprq, Mmus\Papln, Mmus\Vsig1, Mmus\Jam3, Mmus\Fcer1a, Mmus\Vsig8, Mmus\Fcgr4, Mmus\Lrit3, Mmus\Esam, Mmus\Fcgr1, Mmus\Lsamp, Mmus\Pira11, Mmus\Ntm, Mmus\Igsf11, Mmus\Fcgr3, Mmus\Vsig2, Mmus\Cxadr, Mmus\Kirrel, Mmus\Gm1123, Mmus\Kirrel2, Mmus\Igsf5, Mmus\Fcrla, Mmus\Sdk1, Mmus\Igsf9b, Mmus\Fcrlb, Mmus\Kirrel3, Mmus\Opcml, Mmus\Jam2, Mmus\Iglon5, Mmus\Mxra8, Mmus\Fcgr2b, Mmus\Vsir, Mmus\F11r, Mmus\Clmp" "Hsap\IGLON5, Hsap\FCRL4, Hsap\VSIG1, Hsap\MXRA8, Hsap\IGSF5, Hsap\LRIT1, Hsap\FCGR3B, Hsap\FCGR1B, Hsap\KIRREL2, Hsap\LSAMP, Hsap\GPA33, Hsap\FCGR2B, Hsap\NTM, Hsap\SDK1, Hsap\KIRREL, Hsap\VSIG8, Hsap\JAM3, Hsap\PAPLN, Hsap\FCER1A, Hsap\ESAM, Hsap\LOC107987462, Hsap\IGSF11, Hsap\CLMP, Hsap\USH2A, Hsap\PECAM1, Hsap\C1orf204, Hsap\LILRA4, Hsap\C10orf54, Hsap\IGSF9B, Hsap\JAM2, Hsap\FCRLB, Hsap\F11R, Hsap\FCGR2A, Hsap\OPCML, Hsap\FCRLA, Hsap\FCGR3A, Hsap\FCGR1A, Hsap\CXADR, Hsap\LRIT3, Hsap\VSIG2, Hsap\NEGR1, Hsap\KIRREL3, Hsap\LILRB5, Hsap\FCRL6" viable FBgn0027121 l(?)A135 lethal (?) A135 http://flybase.org/reports/FBgn0027121 - gene - - - l(?)A135 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031295 CG4375 - http://flybase.org/reports/FBgn0031295 protein_coding_gene - - - "BcDNA:AT13819, CG4375" - CG4375 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267481 CR45831 - http://flybase.org/reports/FBgn0267481 non_protein_coding_gene - - - CR45831 - CR45831 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014875 Pt8 Protein 8 http://flybase.org/reports/FBgn0014875 - gene - - - Pt8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053418 5SrRNA:CR33418 5SrRNA:CR33418 http://flybase.org/reports/FBgn0053418 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33418, 5SrRNA:CR33418" - CR33418 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011863 tRNA:Gly-GCC-1-5 transfer RNA:Glycine-GCC 1-5 http://flybase.org/reports/FBgn0011863 "FBgn0003778, FBgn0051978, FBgn0060219" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "BG:DS04641.4, AE002690.trna18-GlyGCC, tRNA:G:GCC:AE002690-f, CR31978, tRNA:gly3:35Bb, tRNA[Gly-GCC], chr2L.trna27-GlyGCC, tRNA-Gly-GCC-1-5, tRNA:Gly-GCC-1-5, tRNA:G3:35Bb, GGC" - CR31978 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065939 l(2)SH0117 lethal (2) SH0117 http://flybase.org/reports/FBgn0065939 gene - - - "l(2)SH0117, l(2)SH2 0117" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019670 mor(1)9 mortality gene (1)9 http://flybase.org/reports/FBgn0019670 - gene - - - mor(1)9 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0259287 EP-787 - http://flybase.org/reports/FBgn0259287 gene - - - EP-787 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0040984 CG4440 - http://flybase.org/reports/FBgn0040984 protein_coding_gene - - - "BcDNA:RE16123, CG4440" - CG4440 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC28042 K -0.218650732 0.803158428 0.08515672 -0.358683665 0.631598165 -2.240635291 FBgn0010042 GstD6 Glutathione S transferase D6 http://flybase.org/reports/FBgn0010042 FBgn0038025 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTD6, DmGST25, Gst, GST, gstD25, GstD25, CG4423, GstD6, GSTD6, DmGstd6, gstd6" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG4423 11-Aug-17 DroID_v2017_08 "Drer\gstr, Drer\gstt1b, Drer\gstt2, Drer\gstt1a, Drer\vars, Drer\mars, Drer\eef1e1, Drer\eef1g" "Scer\GTT1, Scer\GTT2, Scer\TEF4, Scer\YGR201C, Scer\CAM1, Scer\URE2" "Cele\gst-35, Cele\gst-34" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Gstt4, Mmus\Vars, Mmus\Mars, Mmus\Eef1g, Mmus\Gstt2, Mmus\Gstt1, Mmus\Gstt3, Mmus\Eef1e1" "Hsap\GSTT1, Hsap\MARS, Hsap\GSTT2, Hsap\EEF1E1, Hsap\GSTT2B, Hsap\EEF1G, Hsap\VARS" adult stage viable FBgn0262610 CG43136 - http://flybase.org/reports/FBgn0262610 protein_coding_gene - - - "CG43136, chrX_5747778_5748511.0" IPR032145:Protein of unknown function DUF4818 CG43136 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032144 CG17633 - http://flybase.org/reports/FBgn0032144 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from sequence or structural similarity with HGNC:2297 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146 neurogenesis ; GO:0022008 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with UniProtKB:P15085 CG17633 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG17633 11-Aug-17 DroID_v2017_08 "Drer\cpo, Drer\cpa6, Drer\cpa1, Drer\cpa2, Drer\cpa4, Drer\cpb1, Drer\cpa5, Drer\cpb2" Scer\ECM14 "Cele\T06A4.1, Cele\T06A4.3, Cele\Y18H1A.9, Cele\Y47G6A.19, Cele\ZC434.9, Cele\W01A8.6, Cele\Y59C2A.1, Cele\suro-1, Cele\F02D8.4" "Xtro\cpo, Xtro\cpa1, Xtro\LOC100487462, Xtro\cpb1, Xtro\cpa3, Xtro\cpb2" "Mmus\Cpa5, Mmus\Cpb1, Mmus\Cpa1, Mmus\Cpa4, Mmus\Cpb2, Mmus\Cpa6, Mmus\Cpa3, Mmus\Cpa2" "Hsap\CPB1, Hsap\CPB2, Hsap\CPA5, Hsap\CPA4, Hsap\CPO, Hsap\CPA1, Hsap\CPA2, Hsap\CPA3, Hsap\CPA6" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0029857 wuho wuho http://flybase.org/reports/FBgn0029857 protein_coding_gene tRNA (guanine-N7-)-methyltransferase activity ; GO:0008176 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000418221 RNA (guanine-N7)-methylation ; GO:0036265 | inferred from electronic annotation with InterPro:IPR028884 spermatogenesis ; GO:0007283 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype female germ cell nucleus ; GO:0001674 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000418221 tRNA methyltransferase complex ; GO:0043527 | inferred from biological aspect of ancestor with PANTHER:PTN000418221 male germ cell nucleus ; GO:0001673 | inferred from direct assay "wuho, CG15897, wh" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR028884:tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit, Trm82" CG15897 11-Aug-17 DroID_v2017_08 Drer\wdr4 Scer\TRM82 Cele\Y102E9.2 - Mmus\Wdr4 Hsap\WDR4 "male sterile,female semi-sterile,viable" "ovariole,egg chamber,spermatozoon,mitochondrion & testis,spermatid cyst" FBgn0261920 EndoA::Hsap\TRIP10 - http://flybase.org/reports/FBgn0261920 engineered_fusion_gene - - - "endoA::Hsap\TRIP10, EndoA::Hsap\TRIP10" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266410 CG45050 - http://flybase.org/reports/FBgn0266410 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000058, InterPro:IPR002653 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002653 molecular_function ; GO:0003674 | no biological data available" biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43674, CG45050, CG33936, anon-EST:fe1B11, anon-EST:fe2G11, drn, CG33188, BcDNA:RE70963, CG33937, CG33187, CG16750, CG16751, CG3393, anon-85Da, CG30492" "IPR000058:Zinc finger, AN1-type, IPR002653:Zinc finger, A20-type" CG45050 11-Aug-17 DroID_v2017_08 "Drer\zgc:77486, Drer\rabgef1, Drer\zfand4, Drer\rabgef1l, Drer\zfand6, Drer\zfand3, Drer\zfand5b, Drer\zfand5a" - "Cele\F22D6.2, Cele\F56F3.4" "Xtro\rabgef1, Xtro\zfand5, Xtro\zfand4, Xtro\zfand6, Xtro\zfand3" "Mmus\Zfand6, Mmus\Zfand5, Mmus\Zfand3, Mmus\Rabgef1, Mmus\Zfand4" "Hsap\ZFAND3, Hsap\RABGEF1, Hsap\ZFAND4, Hsap\ZFAND6, Hsap\ZFAND5" FBgn0050383 CG30383 - http://flybase.org/reports/FBgn0050383 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG30383 - CG30383 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0265612 CR44430 - http://flybase.org/reports/FBgn0265612 non_protein_coding_gene - - - CR44430 - CR44430 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265857 CR44646 - http://flybase.org/reports/FBgn0265857 non_protein_coding_gene - - - CR44646 - CR44646 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000599 E(var)26A Enhancer of variegation 26A http://flybase.org/reports/FBgn0000599 - gene - - - "E-var(2)1, E(var)162, E(var)26A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0014218 l(2)31Da lethal (2) 31Da http://flybase.org/reports/FBgn0014218 - gene - - - l(2)31Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036908 TORIP Torsin interacting protein http://flybase.org/reports/FBgn0036908 protein_coding_gene - - - "CG14103, dLAP1, TORIP, LAP1" - CG14103 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-82a1.6 - - - "Mmus\Tor1aip2, Mmus\Tor1aip1" "Hsap\TOR1AIP1, Hsap\TOR1AIP2" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260286 GSd066 - http://flybase.org/reports/FBgn0260286 gene - - - GSd066 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259656 B1523 - http://flybase.org/reports/FBgn0259656 gene - - - B1523 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263583 CR43608 - http://flybase.org/reports/FBgn0263583 non_protein_coding_gene - - - CR43608 - CR43608 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031205 CG12474 - http://flybase.org/reports/FBgn0031205 protein_coding_gene - - - CG12474 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019789 l(1)14 lethal (1) 14 http://flybase.org/reports/FBgn0019789 - gene - - - l(1)14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038753 CG4459 - http://flybase.org/reports/FBgn0038753 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 CG4459 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG4459 11-Aug-17 DroID_v2017_08 "Drer\oatx, Drer\sv2, Drer\slc22a13, Drer\slc22a17, Drer\slc22a7b.2, Drer\slc22a31, Drer\zmp:0000001102, Drer\slc22a7b.3, Drer\slc22a23, Drer\slc22a16, Drer\slc22a5, Drer\LOC100334012, Drer\LOC101884074, Drer\slc22a15, Drer\slc22a7b.1, Drer\slc22a6l, Drer\zgc:175176, Drer\slc22a21" "Scer\QDR2, Scer\QDR3, Scer\AQR1, Scer\FLR1, Scer\TPO1, Scer\YHK8, Scer\TPO2, Scer\TPO3, Scer\DTR1, Scer\QDR1" "Cele\F45E10.2, Cele\B0252.3, Cele\K05F1.6, Cele\oct-2, Cele\Y82E9BR.16" Xtro\slc22a6 "Mmus\Slc22a23, Mmus\Slc22a16, Mmus\Slc22a6, Mmus\Svop, Mmus\Slc22a14, Mmus\Slc22a17, Mmus\Slc22a29, Mmus\Slc22a19, Mmus\Slc22a26, Mmus\Slc22a2, Mmus\Slc22a8, Mmus\Slc22a27, Mmus\Slc22a28, Mmus\Slc22a4, Mmus\Slc22a7, Mmus\Slc22a30, Mmus\Slc22a22, Mmus\Slc22a15, Mmus\Sv2c, Mmus\Slc22a20" "Hsap\SV2B, Hsap\SV2C, Hsap\SLC22A12, Hsap\SLC22A11, Hsap\SLC22A10, Hsap\SLC22A24, Hsap\SLC22A2, Hsap\SLC22A15, Hsap\SLC22A25, Hsap\SVOP, Hsap\SLC22A8, Hsap\SLC22A17, Hsap\SLC22A1, Hsap\SLC22A31, Hsap\SLC22A9, Hsap\SLC22A23, Hsap\SLC22A6, Hsap\SLC22A7, Hsap\SLC22A16" viable FBgn0054010 CG34010 - http://flybase.org/reports/FBgn0054010 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1022, CG34010" "IPR013653:FR47-like, IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG34010 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-76k16.6, Drer\si:ch73-106k19.2, Drer\si:dkey-76k16.5" - Cele\ZK185.3 - "Mmus\Glyatl3, Mmus\Gm4952, Mmus\Glyat, Mmus\Keg1" "Hsap\GLYAT, Hsap\GLYATL1, Hsap\GLYATL3, Hsap\GLYATL2" FBgn0065322 l(2)SH1914 lethal (2) SH1914 http://flybase.org/reports/FBgn0065322 gene - - - "l(2)SH1914, l(2)SH2 1914" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036254 CG5645 - http://flybase.org/reports/FBgn0036254 protein_coding_gene - "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000375561" 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000375561 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000375561 CG5645 "IPR018034:KRR1 interacting protein 1, IPR024626:Kri1-like, C-terminal" CG5645 11-Aug-17 DroID_v2017_08 Drer\kri1 Scer\KRI1 Cele\F54C9.9 Xtro\kri1 Mmus\Kri1 Hsap\KRI1 "lethal,partially lethal - majority die,visible" trichogen cell DRSC10532 E -0.411041561 -0.150875183 -1.683113587 -0.077360627 -0.258991891 0.017162955 FBgn0265611 CR44429 - http://flybase.org/reports/FBgn0265611 non_protein_coding_gene - - - CR44429 - CR44429 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044085 E(rst)H122 E(rst)H122 http://flybase.org/reports/FBgn0044085 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H122, E(rst)H122" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021884 l(2)k13403 lethal (2) k13403 http://flybase.org/reports/FBgn0021884 - gene - - - l(2)k13403 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023133 WppJ White prepupal locus J http://flybase.org/reports/FBgn0023133 - gene - - - "38, 23, 11, WppJ" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013938 E(sina)3 Enhancer of seven in absentia 3 http://flybase.org/reports/FBgn0013938 - gene - - - E(sina)3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" photoreceptor cell R7 FBgn0033548 CG7637 - http://flybase.org/reports/FBgn0033548 protein_coding_gene telomerase RNA binding ; GO:0070034 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 box H/ACA snoRNA binding ; GO:0034513 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 snRNA pseudouridine synthesis ; GO:0031120 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 positive regulation of telomerase RNA localization to Cajal body ; GO:1904874 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 telomere maintenance via telomerase ; GO:0007004 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 rRNA pseudouridine synthesis ; GO:0031118 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 cellular response to starvation ; GO:0009267 | inferred from expression pattern box H/ACA scaRNP complex ; GO:0072589 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 box H/ACA telomerase RNP complex ; GO:0090661 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 box H/ACA snoRNP complex ; GO:0031429 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 CG7637 "IPR007264:H/ACA ribonucleoprotein complex, subunit Nop10" CG7637 11-Aug-17 DroID_v2017_08 Drer\nop10 Scer\NOP10 Cele\nola-3 Xtro\nop10 Mmus\Nop10 Hsap\NOP10 "viable,visible" "mesothoracic tergum,trichogen cell" FBgn0033158 CG12164 - http://flybase.org/reports/FBgn0033158 protein_coding_gene - - - CG12164 "IPR009078:Ferritin-like superfamily, IPR032134:Protein of unknown function DUF4816" CG12164 11-Aug-17 DroID_v2017_08 - Scer\DDR48 Cele\D1086.9 - Mmus\Sbsn - viable FBgn0015822 T-A7.1 T-A7.1 http://flybase.org/reports/FBgn0015822 - gene - - - T-A7.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024639 l(2)k13217 lethal (2) k13217 http://flybase.org/reports/FBgn0024639 - gene - - - "132/17, l(2)k13217" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034324 CG18538 - http://flybase.org/reports/FBgn0034324 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18538 IPR010512:Protein of unknown function DUF1091 CG18538 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264874 CR44065 - http://flybase.org/reports/FBgn0264874 non_protein_coding_gene - - - CR44065 - CR44065 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016816 l(1)L19 lethal (1) L19 http://flybase.org/reports/FBgn0016816 - gene - - - "l(1)L19, L19" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004149 l(2)57Ac lethal (2) 57Ac http://flybase.org/reports/FBgn0004149 - gene - - - l(2)57Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065891 l(2)SH0218 lethal (2) SH0218 http://flybase.org/reports/FBgn0065891 gene - - - "l(2)SH0218, l(2)SH2 0218" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085289 CG34260 - http://flybase.org/reports/FBgn0085289 protein_coding_gene - - - CG34260 "IPR014756:Immunoglobulin E-set, IPR010512:Protein of unknown function DUF1091" CG34260 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013540 l(2)ry51 lethal (2) ry51 http://flybase.org/reports/FBgn0013540 - gene - - - "l(2)51, l(2)ry51" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029030 l(2)R99 lethal (2) R99 http://flybase.org/reports/FBgn0029030 gene - - - "R99, l(2)R99" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260747 CG5010 - http://flybase.org/reports/FBgn0260747 protein_coding_gene - mitochondrion organization ; GO:0007005 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 "BcDNA:RE73921, CG5010, anon-15Dd" - CG5010 11-Aug-17 DroID_v2017_08 "Drer\chchd2, Drer\chchd10" Scer\MIX17 Cele\har-1 "Xtro\gpat3, Xtro\dnajb4, Xtro\chchd10" "Mmus\Gm13202, Mmus\Chchd2, Mmus\Chchd10" "Hsap\CHCHD2, Hsap\CHCHD10" FBgn0264820 CR44028 - http://flybase.org/reports/FBgn0264820 pseudogene_attribute - - - CR44028 - CR44028 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019970 Indf Indifferent http://flybase.org/reports/FBgn0019970 - gene - - - Indf - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,dominant,recessive,viable,semidominant" FBgn0036685 CG6664 - http://flybase.org/reports/FBgn0036685 protein_coding_gene molecular_function ; GO:0003674 | no biological data available establishment of meiotic spindle orientation ; GO:0051296 | inferred from sequence or structural similarity with WB:WBGene00002994 spindle pole ; GO:0000922 | inferred from sequence or structural similarity with WB:WBGene00002994 condensed chromosome ; GO:0000793 | inferred from sequence or structural similarity with WB:WBGene00002994 CG6664 IPR019152:Protein of unknown function DUF2046 CG6664 11-Aug-17 DroID_v2017_08 "Drer\ccdc6b, Drer\lrrc45, Drer\ccdc6a" - Cele\T09B9.4 "Xtro\ccdc157, Xtro\ccdc6" Mmus\Ccdc6 "Hsap\GOLGA6L10, Hsap\GOLGA8J, Hsap\GOLGA8N, Hsap\CCDC6, Hsap\GOLGA8A, Hsap\LOC100132202, Hsap\GOLGA8K, Hsap\GOLGA6L9, Hsap\GOLGA6L2, Hsap\GOLGA8O, Hsap\GOLGA8M, Hsap\GOLGA6L22, Hsap\GOLGA6L1, Hsap\GOLGA6L3, Hsap\GOLGA8B, Hsap\GOLGA8H, Hsap\LOC645202, Hsap\GOLGA6L4" viable FBgn0263954 BG01004 - http://flybase.org/reports/FBgn0263954 gene - - - BG01004 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective" FBgn0014045 Su(tor)2-187-1 Su(tor)2-187-1 http://flybase.org/reports/FBgn0014045 - gene - - - Su(tor)2-187-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0016644 ER3-2 ER3-2 http://flybase.org/reports/FBgn0016644 - gene - - - ER3-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260117 2L1629 - http://flybase.org/reports/FBgn0260117 gene - - - 2L1629 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0265687 CR44494 - http://flybase.org/reports/FBgn0265687 non_protein_coding_gene - - - "lincRNA.112, CR44494" - CR44494 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067331 2D5 2D5 http://flybase.org/reports/FBgn0067331 gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 2D5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,viable" "wing vein,somatic clone" FBgn0052845 CG32845 - http://flybase.org/reports/FBgn0052845 protein_coding_gene isomerase activity ; GO:0016853 | inferred from electronic annotation with InterPro:IPR000297 - - CG32845 "IPR000297:Peptidyl-prolyl cis-trans isomerase, PpiC-type, IPR001202:WW domain, IPR023058:Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site" CG32845 11-Aug-17 DroID_v2017_08 Drer\pin1 Scer\ESS1 "Cele\Y40B1A.2, Cele\pinn-1" Xtro\pin1 "Mmus\Pin1rt1, Mmus\Pin1" Hsap\PIN1 FBgn0084326 Su(dpp)YE28 Su(dpp)YE28 http://flybase.org/reports/FBgn0084326 gene - - - Su(dpp)YE28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile" FBgn0022033 l(2)k08708 lethal (2) k08708 http://flybase.org/reports/FBgn0022033 - gene - - - l(2)k08708 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267632 CR45970 - http://flybase.org/reports/FBgn0267632 non_protein_coding_gene - - - CR45970 - CR45970 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010272 Sry-rDM17 Sry-related DM17 http://flybase.org/reports/FBgn0010272 - gene DNA binding ; GO:0003677 | inferred from sequence or structural similarity - nucleus ; GO:0005634 | inferred from sequence or structural similarity "DM17, Sry-rDM17" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085769 CR40728 - http://flybase.org/reports/FBgn0085769 rRNA_gene - - - CR40728 - CR40728 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259315 C143 - http://flybase.org/reports/FBgn0259315 gene - - - C143 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing vein,wing,chaeta" FBgn0035471 Sc2 Sc2 http://flybase.org/reports/FBgn0035471 protein_coding_gene "oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from electronic annotation with InterPro:IPR001104 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN002238075" very long-chain fatty acid biosynthetic process ; GO:0042761 | inferred from biological aspect of ancestor with PANTHER:PTN000059180 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001104 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001104 endomembrane system ; GO:0012505 | inferred from direct assay "dSc2, l(3)05634, l(3)63Eb, l(3)SH4, CG10849, Sc2, Ter[CG10849], SC2" "IPR001104:3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal, IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG10849 11-Aug-17 DroID_v2017_08 "Drer\tecrl2b, Drer\tecrb, Drer\tecrl2a, Drer\tecra" Scer\TSC13 "Cele\art-1, Cele\F19H6.4" "Xtro\fam19a5, Xtro\tecr" "Mmus\Tecrl, Mmus\Tecr" "Hsap\TECRL, Hsap\TECR" "viable,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0259665 B1350 - http://flybase.org/reports/FBgn0259665 gene - - - B1350 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,tarsal segment" FBgn0005586 Rab3 Rab3 http://flybase.org/reports/FBgn0005586 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" maintenance of presynaptic active zone structure ; GO:0048790 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | non-traceable author statement regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from sequence or structural similarity with UniProtKB:P63011 regulation of synaptic vesicle fusion to presynaptic membrane ; GO:0031630 | inferred from sequence or structural similarity with UniProtKB:P63011 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 neurotransmitter secretion ; GO:0007269 | non-traceable author statement Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype synaptic vesicle ; GO:0008021 | non-traceable author statement synapse ; GO:0045202 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay presynaptic active zone ; GO:0048786 | colocalizes_with inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 synaptic vesicle ; GO:0008021 | colocalizes_with inferred from direct assay "DRab3, dm-Rab3, AAF58762, DmRab3, drab3, rab3, Rab3A, Drab3, DRAB3, CG7576, Rab3, P25228" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7576 11-Aug-17 DroID_v2017_08 "Drer\rab3c, Drer\rab3db, Drer\rab3ab, Drer\rab3da, Drer\rab3aa, Drer\rab3b" "Scer\YHR022C, Scer\SEC4, Scer\YPT1" "Cele\rab-3, Cele\prmt-4" "Xtro\rab3d, Xtro\rab3c, Xtro\rab3b, Xtro\rab3a" "Mmus\Rab3a, Mmus\Rab3c, Mmus\Rab3b, Mmus\Rab3d" "Hsap\RAB3B, Hsap\RAB3D, Hsap\RAB3C, Hsap\RAB3A" " embryonic stage | stage >=13 , embryonic stage -- adult stage , adult stage " " antenno-maxillary complex

, embryonic central nervous system

, cell body &&of adult brain

" "neuroanatomy defective,neurophysiology defective,viable,fertile" "t-bar,neuromuscular junctionED2076)" FBgn0024560 l(3)L5340 lethal (3) L5340 http://flybase.org/reports/FBgn0024560 - gene - - - l(3)L5340 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085339 CG34310 - http://flybase.org/reports/FBgn0085339 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34310 - CG34310 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067102 GlcT-1 Ceramide glucosyltransferase http://flybase.org/reports/FBgn0067102 protein_coding_gene ceramide glucosyltransferase activity ; GO:0008120 | inferred from direct assay glucosylceramide biosynthetic process ; GO:0006679 | inferred from biological aspect of ancestor with PANTHER:PTN000296098 negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype Golgi membrane ; GO:0000139 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay "DGlcT-1, CG6437, GlcT-1, GlcT, GlcT1, dGlcCerT" "IPR029044:Nucleotide-diphospho-sugar transferases, IPR025993:Ceramide glucosyltransferase" CG6437 11-Aug-17 DroID_v2017_08 Drer\ugcg - "Cele\cgt-2, Cele\cgt-3, Cele\T06C12.12, Cele\cgt-1" Xtro\ugcg Mmus\Ugcg Hsap\UGCG "increased cell death,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0065321 l(2)SH1916 lethal (2) SH1916 http://flybase.org/reports/FBgn0065321 gene - - - "l(2)SH1916, l(2)SH2 1916" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263484 snoRNA:Pi4KIIalpha-a - http://flybase.org/reports/FBgn0263484 snoRNA_gene - - - "snoRNA:Pi4KIIalpha-a, snoRNA:Pl4KIIalpha-a" - CR43599 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058044 CG40044 - http://flybase.org/reports/FBgn0058044 protein_coding_gene - - - CG40044 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264351 CR43807 - http://flybase.org/reports/FBgn0264351 non_protein_coding_gene - - - CR43807 - CR43807 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266759 shg::Rnor\CD2::alpha-Cat - http://flybase.org/reports/FBgn0266759 engineered_fusion_gene - - - shg::Rnor\CD2::alpha-Cat - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039943 CG17168 - http://flybase.org/reports/FBgn0039943 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN002359305 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:30587 production of miRNAs involved in gene silencing by miRNA ; GO:0035196 | inferred from biological aspect of ancestor with PANTHER:PTN001152383 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000592573 CG17168 "IPR000253:Forkhead-associated (FHA) domain, IPR008984:SMAD/FHA domain" CG17168 11-Aug-17 DroID_v2017_08 Drer\snip1 Scer\PML1 Cele\C32E8.5 Xtro\snip1 Mmus\Snip1 Hsap\SNIP1 DRSC20904 K -0.571545314 0.498556612 -1.031827048 0.103853398 -2.895701975 -1.729738696 FBgn0026162 tRNA:Lys-TTT-2-1 transfer RNA:Lysine-TTT 2-1 http://flybase.org/reports/FBgn0026162 "FBgn0003793, FBgn0011901, FBgn0051490, FBgn0060174" tRNA_gene AAA codon-amino acid adaptor activity ; GO:0033443 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033443 cytosol ; GO:0005829 | inferred by curator from GO:0033443 "CR31490, lys5:84ABd, AE002699.trna8-LysTTT, tRNA:K:TTT:AE002699-c, tRNA:K5, BG:DS00276.4, chr3R.trna2-LysTTT, tRNA-Lys-TTT-2-1, tRNA:Lys-TTT-2-1, tRNA:K5:84ABd, AAA" - CR31490 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037912 sea scheggia http://flybase.org/reports/FBgn0037912 protein_coding_gene citrate transmembrane transporter activity ; GO:0015137 | inferred from biological aspect of ancestor with PANTHER:PTN001182669 mitochondrial citrate transport ; GO:0006843 | inferred from mutant phenotype citrate transport ; GO:0015746 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640552 Nebenkern ; GO:0016006 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG31305, anon-WO0140519.12, sea, CG6782, SLC25A1, l(3)EP3364, DmCIC, Sea" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG6782 11-Aug-17 DroID_v2017_08 "Drer\slc25a1b, Drer\si:dkey-178e17.1, Drer\slc25a1a" "Scer\SFC1, Scer\CTP1, Scer\YHM2, Scer\YFR045W" "Cele\K11H3.3, Cele\Y37B11A.3" Xtro\slc25a1 Mmus\Slc25a1 Hsap\SLC25A1 "mitotic cell cycle defective,lethal,viable" "condensed chromosome,embryonic/larval neuroblast,condensed chromosomeMx-1)" FBgn0004750 l(3)89Bc lethal (3) 89Bc http://flybase.org/reports/FBgn0004750 - gene - - - l(3)89Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033019 CG10395 - http://flybase.org/reports/FBgn0033019 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR029523 chromatin remodeling ; GO:0006338 | inferred from electronic annotation with InterPro:IPR029523" "Ino80 complex ; GO:0031011 | inferred from electronic annotation with InterPro:IPR006880, InterPro:IPR029523" "CG10395, mdcds_12730" "IPR007529:Zinc finger, HIT-type, IPR029523:INO80 complex, subunit Ies2, IPR006880:INO80 complex subunit B-like conserved region" CG10395 11-Aug-17 DroID_v2017_08 Drer\ino80b Scer\IES2 - Xtro\ino80b Mmus\Ino80b "Hsap\INO80B, Hsap\WBP1" "viable,body color defective" mesothoracic tergum FBgn0011866 tRNA:Gly-GCC-2-1 transfer RNA:Glycine-GCC 2-1 http://flybase.org/reports/FBgn0011866 "FBgn0003779, FBgn0051980, FBgn0060222" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "BG:DS04641.7, AE002690.trna15-GlyGCC, tRNA:G:GCC:AE002690-c, CR31980, tRNA:gly3:35Be, tRNA[Gly-GCC], chr2L.trna24-GlyGCC, tRNA-Gly-GCC-2-1, tRNA:Gly-GCC-2-1, tRNA:G3:35Be, GGC" - CR31980 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066348 l(3)99DEg lethal (3) 99DEg http://flybase.org/reports/FBgn0066348 gene - - - l(3)99DEg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263497 CR43486 - http://flybase.org/reports/FBgn0263497 non_protein_coding_gene - - - "CR43486, lincRNA.695" - CR43486 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259831 CG34309 - http://flybase.org/reports/FBgn0259831 protein_coding_gene - - - "CG34309, CG14378, Dm_3R:49679, Dm_3R:49681" - CG34309 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010013 Canp Ca[2+]-activated neutral protease http://flybase.org/reports/FBgn0010013 - gene calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | inferred from direct assay - - "CANP, nCAPII, Ca-TPase, Canp" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051776 CG31776 - http://flybase.org/reports/FBgn0051776 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 oligosaccharide biosynthetic process ; GO:0009312 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 - "CG8845a, CG8845, CG31776, dppGalNAcT10" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG31776 11-Aug-17 DroID_v2017_08 "Drer\galnt18b, Drer\galnt7, Drer\galnt16, Drer\poc1bl, Drer\LOC101886587, Drer\galnt12, Drer\LOC100334784, Drer\wbscr17, Drer\galnt3, Drer\galnt2, Drer\galnt8a.1, Drer\LOC568645, Drer\LOC100535692, Drer\LOC101882942, Drer\galnt11, Drer\si:ch211-15e22.3, Drer\galnt9, Drer\galnt6, Drer\galnt8b, Drer\galnt13, Drer\galnt1, Drer\galnt10, Drer\LOC103910015, Drer\galnt14" - "Cele\gly-9, Cele\gly-7, Cele\gly-11, Cele\gly-10, Cele\gly-3" "Xtro\galnt6.1, Xtro\galnt1, Xtro\galnt12, Xtro\galnt9, Xtro\galnt7, Xtro\galnt2, Xtro\galnt4, Xtro\galnt15, Xtro\galnt16, Xtro\galnt13, Xtro\galnt14, Xtro\wbscr17, Xtro\galnt10" "Mmus\Galntl5, Mmus\Wbscr17, Mmus\Galntl6, Mmus\Galnt16, Mmus\Galnt13, Mmus\Galnt18, Mmus\Galnt2, Mmus\Galnt12, Mmus\Galnt14, Mmus\Galnt5, Mmus\Galnt9, Mmus\Galnt4, Mmus\Galnt10, Mmus\Galnt15, Mmus\Galnt3, Mmus\Galnt11, Mmus\Galnt6, Mmus\Galnt1, Mmus\Galnt7" "Hsap\GALNT16, Hsap\GALNT4, Hsap\GALNT11, Hsap\GALNT7, Hsap\GALNT13, Hsap\GALNT5, Hsap\GALNT3, Hsap\GALNT18, Hsap\GALNT10, Hsap\GALNT9, Hsap\GALNT6, Hsap\GALNT15, Hsap\GALNT2, Hsap\GALNTL5, Hsap\GALNT8, Hsap\GALNT14, Hsap\GALNTL6, Hsap\WBSCR17, Hsap\GALNT12, Hsap\POC1B-GALNT4, Hsap\GALNT1" viable FBgn0032670 CG5783 - http://flybase.org/reports/FBgn0032670 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 - - CG5783 "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG5783 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-76k16.5, Drer\si:dkey-76k16.6, Drer\si:ch73-106k19.2" Scer\TEM1 "Cele\ZK185.3, Cele\gip-1, Cele\let-756" - "Mmus\Keg1, Mmus\Glyatl3, Mmus\Glyat, Mmus\Rin1, Mmus\Gm4952" "Hsap\GLYAT, Hsap\RIN1, Hsap\GLYATL3, Hsap\TSC1, Hsap\GLYATL1, Hsap\GLYATL2" viable FBgn0053911 CG33911 - http://flybase.org/reports/FBgn0053911 protein_coding_gene - - - "BG:DS07295.4, DS07295.4, CG33911" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266277 CR44962 - http://flybase.org/reports/FBgn0266277 non_protein_coding_gene - - - CR44962 - CR44962 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039437 TwdlL TweedleL http://flybase.org/reports/FBgn0039437 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlL, CG6447, TwdIL" IPR004145:Domain of unknown function DUF243 CG6447 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022313 l(1)H22.1 lethal (1) H22.1 http://flybase.org/reports/FBgn0022313 - gene - - - "H22.1, l(1)H22.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040742 CG15606 - http://flybase.org/reports/FBgn0040742 protein_coding_gene - - - CG15606 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031331 CG5440 - http://flybase.org/reports/FBgn0031331 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12478 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12478 cellular_component ; GO:0005575 | no biological data available CG5440 "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG5440 11-Aug-17 DroID_v2017_08 "Drer\ube2e1, Drer\ube2d3, Drer\ube2d1b, Drer\ube2d4, Drer\ube2d2, Drer\ube2t, Drer\ube2d1a, Drer\ube2e2, Drer\ube2e3, Drer\ube2na, Drer\ube2nb" "Scer\UBC4, Scer\PEX4, Scer\UBC13, Scer\UBC5" - "Xtro\ube2e3, Xtro\ube2d1, Xtro\ube2n, Xtro\ube2d4, Xtro\ube2d3, Xtro\ube2e1, Xtro\ube2e2" "Mmus\Ube2dnl2, Mmus\Ube2d1, Mmus\Ube2n, Mmus\Ube2d3, Mmus\Ube2d2b, Mmus\Ube2dnl1, Mmus\Ube2e3, Mmus\Ube2e1, Mmus\Ube2e2, Mmus\Ube2t" "Hsap\UBE2D4, Hsap\UBE2N, Hsap\UBE2E3, Hsap\UBE2D3, Hsap\UBE2D2, Hsap\UBE2E1, Hsap\UBE2D1, Hsap\UBE2Q2L, Hsap\UBE2E2, Hsap\UBE2T, Hsap\UBE2NL" FBgn0003277 RpII215 RNA polymerase II 215kD subunit http://flybase.org/reports/FBgn0003277 "FBgn0001616, FBgn0026704" protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000684, InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007073, InterPro:IPR007075, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083 RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000453465 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from direct assay" mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000002299 "polytene chromosome puff ; GO:0005703 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000002299 DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay" "Pol II, Pol II CTD, RNApol, CTD, Pol IIa, Pol IIo[ser2], Pol IIo[ser5], PolII, Rpb1, pol II, RNAP, RNAPII, 8WG16, RNAP II, H5, polII, dRPB1, RNA Pol II, POL, RNA pol II, CG1554, RNA polII, l(1)G0040, II, RPB1, RNAP II LS, RNApolII, RNA PolII, Ubl, Rpll215, 5, l(1)L5, L5, l(1)DF912, RpII, l(1)DC912, l(1)10Ca, RpII215, Pol IIo, RNAPII0, RNA pol IIo, Pol II[ser2], PolIIo, RNA PolI 215, Pol II0[ser5], Pol II0[ser2], Pol-IIa, RNA Pol II CTD, dRpb1, Pol IIo[Ser2], RPII215, RNApol2, Pol II Ser5P, IIo, Pol II Ser5p, rpII1, PolIIo[ser2], PolIIo[ser5], PolIIa, alphaPol IIo[ser2], RNA-PolII, Ser5-P Pol II, Poll II, Pol-II, RNA-Pol" "IPR000684:RNA polymerase II, heptapeptide repeat, eukaryotic, IPR000722:RNA polymerase, alpha subunit, IPR006592:RNA polymerase, N-terminal, IPR007066:RNA polymerase Rpb1, domain 3, IPR007073:RNA polymerase Rpb1, domain 7, IPR007075:RNA polymerase Rpb1, domain 6, IPR007080:RNA polymerase Rpb1, domain 1, IPR007081:RNA polymerase Rpb1, domain 5, IPR007083:RNA polymerase Rpb1, domain 4" CG1554 11-Aug-17 DroID_v2017_08 "Drer\polr2a, Drer\ubxn7, Drer\polr3a" "Scer\RPO21, Scer\RPO31" "Cele\ama-1, Cele\rpc-1" "Xtro\ubxn7, Xtro\polr3a" "Mmus\Polr3a, Mmus\Polr2a, Mmus\Ubxn7" "Hsap\UBXN7, Hsap\POLR2A, Hsap\SLC35G6, Hsap\POLR3A" "lethal,recessive,heat sensitive,viable,visible,dominant,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,chemical resistant,female sterile,cold sensitive,lethal - all die before end of larval stage,some die during larval stage,male fertile,partially,cell lethal,germline clone,male sterile,cell lethalcell lethal,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "capitellum,ovariole,germline clone,oocyte,prothoracic tarsal segment 2,male,haltere" DRSC20280 EK -0.264436424 0.311638996 1.50902253 -2.929978114 1.809341559 5.322892763 FBgn0028243 l(3)S000721 lethal (3) S000721 http://flybase.org/reports/FBgn0028243 gene - - - "0007/21, l(3)S000721" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0000077 amx almondex http://flybase.org/reports/FBgn0000077 FBgn0028503 protein_coding_gene - mesoderm development ; GO:0007498 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement ectodermal cell fate determination ; GO:0001713 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from genetic interaction with N spanning component of plasma membrane ; GO:0044214 | inferred from sequence model "fs(1)amx, CG12127, BcDNA:GH02974, amx" IPR007829:TM2 domain CG12127 11-Aug-17 DroID_v2017_08 Drer\tm2d3 - "Cele\Y66D12A.21, Cele\C41D11.9" Xtro\tm2d3 "Mmus\Tm2d3, Mmus\Tm2d1" "Hsap\TM2D3, Hsap\TM2D1" "viable,fertile,lethal - all die before end of embryonic stage,neurogenic phenotype,some die during embryonic stage,visible,recessive,lethal,rescuable maternal effect,female sterile,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage" "eye,epidermis,nervous system,ommatidium,thorax,rescuable maternal effect,ectoderm,embryonic epidermis,sensory mother cell,neuroblast,maternal effect,supernumerary" FBgn0000236 bu bulging http://flybase.org/reports/FBgn0000236 - gene - - - bu - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,partially lethal - majority die" eye FBgn0001245 hypoG hypoactive G http://flybase.org/reports/FBgn0001245 - gene - - - hypoG - - 11-Aug-17 DroID_v2017_08 - - - - - - "hypoactive,optomotor response defective,locomotor behavior defective,flight defective" FBgn0037082 CG5664 - http://flybase.org/reports/FBgn0037082 protein_coding_gene - - - CG5664 - CG5664 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032020 strat stratum http://flybase.org/reports/FBgn0032020 protein_coding_gene guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 zinc ion binding ; GO:0008270 | inferred from sequence or structural similarity with UniProtKB:P47224 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR007515 post-Golgi vesicle-mediated transport ; GO:0006892 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 membrane ; GO:0016020 | inferred from sequence or structural similarity with SGD:S000006221 cytosol ; GO:0005829 | inferred from sequence or structural similarity with SGD:S000006221 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 "BcDNA:RE45155, CG7787, Strat, strat" "IPR007515:Mss4, IPR011057:Mss4-like" CG7787 11-Aug-17 DroID_v2017_08 "Drer\rabif, Drer\lyplal1" Scer\DSS4 "Cele\mdt-9, Cele\ZK970.8" Xtro\rabif Mmus\Rabif Hsap\RABIF "partially lethal - majority die,some die during pupal stage" FBgn0015950 hsk helter-skelter http://flybase.org/reports/FBgn0015950 - gene - - - hsk - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile" embryonic/larval brain FBgn0028045 l(3)S097001 lethal (3) S097001 http://flybase.org/reports/FBgn0028045 gene - - - "1087/09, 1450/06, 0970/01, l(3)S108709, l(3)S097001" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" FBgn0069149 mcl(3)Z3426 mcl(3)Z3426 http://flybase.org/reports/FBgn0069149 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3426 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0033712 mIF3 mitochondrial translation initiation factor 3 http://flybase.org/reports/FBgn0033712 protein_coding_gene "ribosomal small subunit binding ; GO:0043024 | inferred from sequence or structural similarity with UniProtKB:Q9H2K0 translation factor activity, RNA binding ; GO:0008135 | inferred from sequence or structural similarity with UniProtKB:Q9H2K0 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000003667" ribosome disassembly ; GO:0032790 | inferred from sequence or structural similarity with UniProtKB:Q9H2K0 mitochondrial translational initiation ; GO:0070124 | inferred from sequence or structural similarity with UniProtKB:Q9H2K0 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000003667 mitochondrion ; GO:0005739 | traceable author statement "CG13163, mIF3" "IPR001288:Translation initiation factor 3, IPR019815:Translation initiation factor 3, C-terminal" CG13163 11-Aug-17 DroID_v2017_08 Drer\mtif3 - - - Mmus\Mtif3 Hsap\MTIF3 viable FBgn0028611 l(2)W14 lethal (2) W14 http://flybase.org/reports/FBgn0028611 gene - - - "l(2R)W14, l(2)W14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053736 snmRNA:430:CR33736 snmRNA:430:CR33736 http://flybase.org/reports/FBgn0053736 non_protein_coding_gene - - - "CR33736, snmRNA:430:CR33736" - CR33736 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263240 Coop Corepressor of Pangolin http://flybase.org/reports/FBgn0263240 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 transcription factor binding ; GO:0008134 | inferred from physical interaction with pan RNA polymerase II transcription corepressor activity ; GO:0001106 | inferred from direct assay negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with pan nucleus ; GO:0005634 | inferred from direct assay "CG1621, Coop, coop" "IPR004210:BESS motif, IPR006578:MADF domain" CG1621 11-Aug-17 DroID_v2017_08 "Drer\zgc:152938, Drer\si:ch211-207i20.3, Drer\LOC100330838" - "Cele\madf-10, Cele\madf-4, Cele\madf-8, Cele\madf-9, Cele\madf-3, Cele\madf-2, Cele\madf-5" - - - FBgn0001255 ImpE3 Ecdysone-inducible gene E3 http://flybase.org/reports/FBgn0001255 "FBgn0037542, FBgn0040525" protein_coding_gene - imaginal disc eversion ; GO:0007561 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity extrinsic component of membrane ; GO:0019898 | traceable author statement "CG2723, CG11046, Imp-E3, IMP-E3, ImpE3" - CG2723 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC16716 IE 1.217114555 2.211865468 -0.711556829 1.843291439 0.066562464 0.954554432 FBgn0069441 E(zip)18-5 E(zip)18-5 http://flybase.org/reports/FBgn0069441 gene - - - "18-5, E(zip)18-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260283 GSd322 - http://flybase.org/reports/FBgn0260283 gene - - - GSd322 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033990 CG10265 - http://flybase.org/reports/FBgn0033990 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG30474, CG10265" - CG10265 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC05986 E -0.442621924 -0.052328941 0.469293004 1.514876172 -0.362199737 -0.51456077 FBgn0034730 ppk12 pickpocket 12 http://flybase.org/reports/FBgn0034730 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG10972, PPK12, ppk12" IPR001873:Epithelial sodium channel CG10972 11-Aug-17 DroID_v2017_08 "Drer\smarcd3b, Drer\asic4b, Drer\asic4a, Drer\asic1b, Drer\asic1a, Drer\smarcd3a, Drer\asic2, Drer\asic1c, Drer\smarcd1" "Scer\RSC6, Scer\SNF12" "Cele\asic-2, Cele\acd-1, Cele\delm-1, Cele\acd-4, Cele\acd-3, Cele\flr-1, Cele\acd-2, Cele\delm-2, Cele\ham-3, Cele\mec-10, Cele\del-7, Cele\asic-1, Cele\del-4, Cele\swsn-2.2, Cele\acd-5, Cele\del-8, Cele\del-6" "Xtro\scnn1b, Xtro\scnn1g, Xtro\scnn1a, Xtro\asic1, Xtro\scnn1d, Xtro\asic5, Xtro\asic4" "Mmus\Asic1, Mmus\Scnn1a, Mmus\Asic4, Mmus\Scnn1b, Mmus\Asic3, Mmus\Scnn1g, Mmus\Asic5, Mmus\Smarcd3, Mmus\Smarcd1, Mmus\Smarcd2, Mmus\Asic2" "Hsap\ASIC3, Hsap\ASIC1, Hsap\SMARCD2, Hsap\ASIC5, Hsap\SMARCD1, Hsap\ASIC2, Hsap\SCNN1A, Hsap\ASIC4, Hsap\SCNN1B, Hsap\SCNN1G, Hsap\SMARCD3, Hsap\SCNN1D" viable DRSC04086 I -0.497343513 -1.795308451 -0.956148973 0.645294904 0.25377 -0.702192321 FBgn0067751 l(1)G0189 lethal (1) G0189 http://flybase.org/reports/FBgn0067751 gene - - - l(1)G0189 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0083009 snoRNA:Psi28S-1135d snoRNA:Psi28S-1135d http://flybase.org/reports/FBgn0083009 snoRNA_gene - - - "snoRNA:Psi28S-1135d, Psi28S-1135d, psi28S-1135d, CR34603" - CR34603 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019798 l(1)07 lethal (1) 07 http://flybase.org/reports/FBgn0019798 - gene - - - l(1)07 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015263 Mst23Ea Male-specific transcript 23Ea http://flybase.org/reports/FBgn0015263 - gene - - - Mst23Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083085 kur kur http://flybase.org/reports/FBgn0083085 gene - - - "kurzkern, kur" - - 11-Aug-17 DroID_v2017_08 - - - - - - "nucleus | gastrula stage,nucleus | blastoderm stage" FBgn0267759 CR46090 - http://flybase.org/reports/FBgn0267759 non_protein_coding_gene - - - CR46090 - CR46090 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038414 CG6901 - http://flybase.org/reports/FBgn0038414 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 CG6901 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG6901 11-Aug-17 DroID_v2017_08 "Drer\slc2a6, Drer\slc2a10, Drer\slc2a13b, Drer\slc2a8, Drer\LOC101882338, Drer\slc2a12" "Scer\GEX2, Scer\SNF3, Scer\HXT5, Scer\GEX1, Scer\ATR1, Scer\GAL2, Scer\ENB1, Scer\YMR279C, Scer\HXT2, Scer\ITR1, Scer\HXT13, Scer\MAL11, Scer\SGE1, Scer\YDR387C, Scer\YFL040W, Scer\VBA1, Scer\MAL31, Scer\RGT2, Scer\HXT15, Scer\HXT11, Scer\HXT1, Scer\HXT17, Scer\HXT3, Scer\HXT4, Scer\HXT9, Scer\MPH3, Scer\AZR1, Scer\HXT8, Scer\HXT14, Scer\VBA5, Scer\YDL199C, Scer\VBA2, Scer\HXT6, Scer\HXT16, Scer\HXT10, Scer\VBA4, Scer\MPH2, Scer\HXT7, Scer\VBA3, Scer\STL1, Scer\ITR2" "Cele\hmit-1.2, Cele\fgt-1" "Xtro\slc2a8, Xtro\slc2a12, Xtro\slc2a6, Xtro\slc2a10" "Mmus\Slc2a10, Mmus\Slc2a13, Mmus\Slc2a6, Mmus\Slc2a12, Mmus\Slc2a8" "Hsap\SLC2A12, Hsap\SLC2A8, Hsap\SLC2A10, Hsap\SLC2A13, Hsap\SLC2A6" viable FBgn0267642 CR45980 - http://flybase.org/reports/FBgn0267642 non_protein_coding_gene - - - CR45980 - CR45980 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043981 Su(rst)G67 Su(rst)G67 http://flybase.org/reports/FBgn0043981 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "G67, Su(rst)G67" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039056 CenB1A Centaurin beta 1A http://flybase.org/reports/FBgn0039056 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 GTPase activator activity ; GO:0005096 | inferred from sequence model phospholipid binding ; GO:0005543 | inferred from sequence or structural similarity with HGNC:16922 regulation of GTPase activity ; GO:0043087 | inferred from sequence model cell morphogenesis ; GO:0000902 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:16469 "CenB1A, CG6742, Cen1ba, cenB1A, ACAP" "IPR001164:Arf GTPase activating protein, IPR001849:Pleckstrin homology domain, IPR002110:Ankyrin repeat, IPR011993:PH domain-like, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR020683:Ankyrin repeat-containing domain" CG6742 11-Aug-17 DroID_v2017_08 "Drer\agap1, Drer\appl1, Drer\acap3a, Drer\asap1b, Drer\acap1, Drer\asap2b, Drer\acap2, Drer\asap2a, Drer\acap3b, Drer\appl2, Drer\zgc:162872, Drer\si:ch211-168b3.1, Drer\unm_sa1614" "Scer\AGE1, Scer\AGE2" "Cele\cnt-2, Cele\cnt-1" "Xtro\asap2, Xtro\acap1, Xtro\acap3, Xtro\appl2, Xtro\asap1, Xtro\appl1, Xtro\acap2" "Mmus\Appl1, Mmus\9030624G23Rik, Mmus\Agap3, Mmus\Asap2, Mmus\Acap1, Mmus\Appl2, Mmus\Asap1, Mmus\Acap2, Mmus\Agap1, Mmus\Asap3, Mmus\Acap3" "Hsap\AGAP1, Hsap\ACAP2, Hsap\ACAP3, Hsap\AGAP3, Hsap\ASAP3, Hsap\APPL1, Hsap\APPL2, Hsap\ACAP1, Hsap\ASAP2, Hsap\ASAP1" "viable,visible" trichogen cell FBgn0266596 CR45121 - http://flybase.org/reports/FBgn0266596 non_protein_coding_gene - - - CR45121 - CR45121 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060497 l(3)S107705b lethal (3) S107705b http://flybase.org/reports/FBgn0060497 gene - - - "1077/05, l(3)S107705b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0083091 fermata fermata http://flybase.org/reports/FBgn0083091 gene - meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype - "fermata, fer" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern" FBgn0002405 l(3)99Df lethal (3) 99Df http://flybase.org/reports/FBgn0002405 - gene - - - l(3)99Df - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037017 CG4074 - http://flybase.org/reports/FBgn0037017 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000260563 protein transporter activity ; GO:0008565 | contributes_to inferred from sequence or structural similarity with SGD:S000003589 "intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000260563 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with SGD:S000003589" "endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000003589 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000260563 retromer, cargo-selective complex ; GO:0030906 | inferred from sequence or structural similarity with SGD:S000003589" "CG4074, DmDSCR3, DSCR3" IPR028934:Vacuolar protein sorting protein 26 related CG4074 11-Aug-17 DroID_v2017_08 Drer\dscr3 Scer\PEP8 - Xtro\dscr3 Mmus\Dscr3 Hsap\DSCR3 "viable,fertile" FBgn0032404 RpL7-like Ribosomal protein L7-like http://flybase.org/reports/FBgn0032404 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement "neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000463 | inferred from biological aspect of ancestor with PANTHER:PTN000897517 cytoplasmic translation ; GO:0002181 | traceable author statement" cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "RpL7-like, CG5317" "IPR005998:Ribosomal protein L7, eukaryotic, IPR016082:Ribosomal protein L30, ferredoxin-like fold domain" CG5317 11-Aug-17 DroID_v2017_08 "Drer\rpl7l1, Drer\rpl7" "Scer\RPL7B, Scer\RPL7A, Scer\RLP7" Cele\rpl-7 Xtro\rpl7 "Mmus\Rpl7l1, Mmus\Rpl7, Mmus\Npsr1" "Hsap\NPSR1, Hsap\RPL7L1, Hsap\RPL7" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell,embryonic/larval salivary gland" FBgn0264311 l(2)k14501 - http://flybase.org/reports/FBgn0264311 gene - - - l(2)k14501 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005288 mei-1946 meiotic 1946 http://flybase.org/reports/FBgn0005288 - gene - - - "1946, mei-1946" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0005251 l(3)R350 lethal of Roberts 350 http://flybase.org/reports/FBgn0005251 - gene - - - "l(3)350, l(3)R350" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0037205 BoYb Brother of Yb http://flybase.org/reports/FBgn0037205 protein_coding_gene - "negative regulation of transposition, RNA-mediated ; GO:0010526 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | inferred from biological aspect of ancestor with PANTHER:PTN001476977" Yb body ; GO:0070725 | inferred from direct assay "CG11133, BoYb" "IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014014:RNA helicase, DEAD-box type, Q motif" CG11133 11-Aug-17 DroID_v2017_08 "Drer\ddx59, Drer\ddx21, Drer\ddx5, Drer\LOC556764, Drer\tdrd12" "Scer\DBP2, Scer\DBP3" - "Xtro\ddx59, Xtro\gpr149, Xtro\ddx17, Xtro\ddx21, Xtro\ddx5" "Mmus\Ddx17, Mmus\Ddx5, Mmus\Ddx21, Mmus\Tdrd12, Mmus\Ddx50, Mmus\Gpr149, Mmus\Ddx59" "Hsap\DDX50, Hsap\DDX21, Hsap\DDX17, Hsap\TDRD12, Hsap\DDX5, Hsap\GPR149, Hsap\DDX59" "female semi-sterile,female fertile" FBgn0032465 CG12404 - http://flybase.org/reports/FBgn0032465 protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006977 CG12404 IPR006977:Yip1 domain CG12404 11-Aug-17 DroID_v2017_08 "Drer\yipf5, Drer\zgc:123321" Scer\YIP1 Cele\F32D8.14 Xtro\yipf5 "Mmus\Yipf7, Mmus\Yipf5" "Hsap\YIPF5, Hsap\YIPF7" lethal FBgn0265763 CR44570 - http://flybase.org/reports/FBgn0265763 non_protein_coding_gene - - - CR44570 - CR44570 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260268 GSd450 - http://flybase.org/reports/FBgn0260268 gene - - - GSd450 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,intersegmental nerve,segmental nerve" FBgn0044001 Su(rst)C379 Su(rst)C379 http://flybase.org/reports/FBgn0044001 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C379, Su(rst)C379" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040466 Dlip2 Dorsal interacting protein 2 http://flybase.org/reports/FBgn0040466 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612 protein binding ; GO:0005515 | inferred from physical interaction with dl protein binding ; GO:0005515 | inferred from physical interaction with Sep1 inferred from physical interaction with Sep2 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "DIP2, dmDIP2, dip2, sip4, CG9771, Dlip2, Dip2" "IPR006612:Zinc finger, C2CH-type" CG9771 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0060900 l(3)S044205b lethal (3) S044205b http://flybase.org/reports/FBgn0060900 gene - - - "0442/05, l(3)S044205b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085291 CR34262 - http://flybase.org/reports/FBgn0085291 pseudogene_attribute - - - CR34262 - CR34262 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024268 acd(2)5D10 auditory courtship defective 5D10 http://flybase.org/reports/FBgn0024268 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "5D10, acd(2)5D10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective,touch sensitivity defective" FBgn0040100 lectin-24Fb lectin-24Fb http://flybase.org/reports/FBgn0040100 gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity - - "AC004373b, AC 004373B, lectin-24Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033789 CG13324 - http://flybase.org/reports/FBgn0033789 protein_coding_gene - - - CG13324 IPR031734:Transcription activator MBF2 CG13324 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085748 CR40573 - http://flybase.org/reports/FBgn0085748 rRNA_gene - - - CR40573 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000837 fs(1)M21 female sterile (1) M21 http://flybase.org/reports/FBgn0000837 - gene - - - fs(1)M21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0030347 CG15739 - http://flybase.org/reports/FBgn0030347 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000002395 alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with SGD:S000002395 phosphatase activity ; GO:0016791 | inferred from direct assay dephosphorylation ; GO:0016311 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002395 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000445812 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002395 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002395 "CG15739, Phos15739, FPPase, 17945012" "IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG15739 11-Aug-17 DroID_v2017_08 "Drer\nipsnap1, Drer\gbas, Drer\pdxp, Drer\lhpp, Drer\pgp" Scer\PHO13 "Cele\K02D10.1, Cele\C53A3.2, Cele\C13C4.4, Cele\F44E7.2, Cele\C45E5.1, Cele\K09H11.7" Xtro\nipsnap1 "Mmus\Gbas, Mmus\Nipsnap1, Mmus\Pgp, Mmus\Lhpp, Mmus\Pdxp" "Hsap\LHPP, Hsap\PDXP, Hsap\PGP, Hsap\NIPSNAP1, Hsap\GBAS" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039642 CG11882 - http://flybase.org/reports/FBgn0039642 protein_coding_gene - - - CG11882 IPR028043:Protein of unknown function DUF4506 CG11882 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259272 C800 - http://flybase.org/reports/FBgn0259272 gene - - - C800 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing FBgn0278597 CR46267 - http://flybase.org/reports/FBgn0278597 non_protein_coding_gene - - - CR46267 - CR46267 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027627 qed qed http://flybase.org/reports/FBgn0027627 - gene - - - qed - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,ventral,maxillary palpus" FBgn0267057 CR45501 - http://flybase.org/reports/FBgn0267057 non_protein_coding_gene - - - CR45501 - CR45501 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042695 Nuk Nuk http://flybase.org/reports/FBgn0042695 gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Dnuk, Nuk" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027203 l(1)G0423 lethal (1) G0423 http://flybase.org/reports/FBgn0027203 - gene - - - l(1)G0423 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0028912 tRNA:Pro-AGG-1-2 transfer RNA:Proline-AGG 1-2 http://flybase.org/reports/FBgn0028912 tRNA_gene CCU codon-amino acid adaptor activity ; GO:0033421 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033421 cytosol ; GO:0005829 | inferred by curator from GO:0033421 "BG:DS01486.2, tRNA:pro, AE002690.trna11-ProAGG, tRNA:P:AGG:AE002690-b, CR31983, chr2L.trna20-ProAGG, tRNA-Pro-AGG-1-2, tRNA:Pro-AGG-1-2, tRNA:P:35Ba, CCU" - CR31983 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058346 CG40346 - http://flybase.org/reports/FBgn0058346 protein_coding_gene - - - CG40346 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011233 tho thousand points of light http://flybase.org/reports/FBgn0011233 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "tho86E, ms(3)04112, tho" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,partially lethal - majority die" "spermatozoon,spermatid & nucleus,primary spermatocyte cyst,spermatid" FBgn0264358 CR43810 - http://flybase.org/reports/FBgn0264358 non_protein_coding_gene - - - CR43810 - CR43810 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000096 ants antennas http://flybase.org/reports/FBgn0000096 - gene - - - "ants, Ants" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,good,visible,recessive" antenna FBgn0013755 Bro Brother http://flybase.org/reports/FBgn0013755 - protein_coding_gene protein heterodimerization activity ; GO:0046982 | traceable author statement transcription factor binding ; GO:0008134 | traceable author statement transcription coactivator activity ; GO:0003713 | inferred from direct assay compound eye development ; GO:0048749 | traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "bro, rpbeta1, CG7960, Bro" "IPR003417:Core binding factor, beta subunit" CG7960 11-Aug-17 DroID_v2017_08 Drer\cbfb - Cele\bro-1 Xtro\cbfb Mmus\Cbfb Hsap\CBFB embryonic stage

ubiquitous "viable,fertile" embryonic/first instar larval cuticle FBgn0000957 fs(2)E4 female sterile (2) E4 http://flybase.org/reports/FBgn0000957 - gene - - - "fs2.4, fs(2)E4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "female reproductive system,egg" FBgn0264518 CR43917 - http://flybase.org/reports/FBgn0264518 non_protein_coding_gene - - - "CR43917, lincRNA.429" - CR43917 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021777 md1 muscle disorganised 1 http://flybase.org/reports/FBgn0021777 - gene - - - md1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061435 CG30270 - http://flybase.org/reports/FBgn0061435 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT30770, CG30270" IPR031931:Protein of unknown function DUF4768 CG30270 11-Aug-17 DroID_v2017_08 "Drer\hexb, Drer\hexa" - - Xtro\hexb "Mmus\Hexb, Mmus\Hexa" "Hsap\HEXB, Hsap\HEXA" DRSC22890 I 1.190272924 -1.629845329 0.23415512 -0.059303735 0.134884508 -0.039804856 FBgn0035427 ckd cracked http://flybase.org/reports/FBgn0035427 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "ckd, EP(2)3139, EP(3)0714, EP714, EP3139, BcDNA:RH52423, CG14959, CKD" IPR002557:Chitin binding domain CG14959 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - "viable,fertile,visible" eye FBgn0027976 l(3)S139308b lethal (3) S139308b http://flybase.org/reports/FBgn0027976 gene - - - "1393/08, l(3)S139308, l(3)S139308b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0031545 CG3213 - http://flybase.org/reports/FBgn0031545 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "bs30c03.y1, CG3213" - CG3213 11-Aug-17 DroID_v2017_08 Drer\odf2a - - Xtro\odf2 Mmus\Odf2 Hsap\ODF2 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC00576 IEK 1.658188609 0.394044859 1.857874755 1.53639671 2.666516006 3.669221064 FBgn0032051 CG13097 - http://flybase.org/reports/FBgn0032051 protein_coding_gene - maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000424645 cellular response to starvation ; GO:0009267 | inferred from expression pattern small nucleolar ribonucleoprotein complex ; GO:0005732 | inferred from electronic annotation with InterPro:IPR012173 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000424645 Mpp10 complex ; GO:0034457 | inferred from biological aspect of ancestor with PANTHER:PTN000424645 CG13097 "IPR012173:U3 small nucleolar ribonucleoprotein complex, subunit Mpp10" CG13097 11-Aug-17 DroID_v2017_08 Drer\mphosph10 Scer\MPP10 Cele\Y75B8A.7 Xtro\mphosph10 Mmus\Mphosph10 Hsap\MPHOSPH10 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0085306 CG34277 - http://flybase.org/reports/FBgn0085306 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34277 - CG34277 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058329 CG40329 - http://flybase.org/reports/FBgn0058329 protein_coding_gene - - - CG40329 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019782 l(1)24 lethal (1) 24 http://flybase.org/reports/FBgn0019782 - gene - - - l(1)24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021770 nori-1 nori-1 http://flybase.org/reports/FBgn0021770 - gene - - - nori-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,heat sensitive" FBgn0010901 l(3)06743 lethal (3) 06743 http://flybase.org/reports/FBgn0010901 - gene - - - l(3)06743 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083314 E(smoDN)1333 Enhancer of smoDN 1333 http://flybase.org/reports/FBgn0083314 gene - - - E(smoDN)1333 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051902 Spn28Da Serpin 28Da http://flybase.org/reports/FBgn0051902 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG12318, Spn28Da, CG31902" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG31902 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-416d2.3, Drer\si:ch211-186e20.7, Drer\serpine1, Drer\serpina7, Drer\serpina10a, Drer\zgc:174259, Drer\serpinb1, Drer\serpine3, Drer\serpinb14, Drer\serpina1l, Drer\serpinh1b, Drer\serpinc1, Drer\serpinb1l4, Drer\serpind1, Drer\serpini1, Drer\serpine2, Drer\serpinb1l2, Drer\serpinb1l1, Drer\serpinh1a, Drer\serpinb1l3, Drer\serpinh2, Drer\zgc:173729" - "Cele\srp-7, Cele\srp-2, Cele\srp-3, Cele\srp-6, Cele\srp-8, Cele\srp-1" "Xtro\serpina10, Xtro\serpina3k, Xtro\serpine1, Xtro\serpinb4, Xtro\serpina3, Xtro\serpina1, Xtro\serpini2, Xtro\serpinb11, Xtro\serpinb6, Xtro\serpinb1, Xtro\serpind1, Xtro\serpine2, Xtro\serpinc1, Xtro\serpini1, Xtro\serpina3m, Xtro\serpinb5" "Mmus\Serpina10, Mmus\Serpinb2, Mmus\Serpinb3b, Mmus\Serpine1, Mmus\Serpini2, Mmus\Serpinb7, Mmus\Serpine2, Mmus\Serpina12, Mmus\Serpina3k, Mmus\Serpinb6d, Mmus\Serpind1, Mmus\Serpini1, Mmus\Serpinb6a, Mmus\Serpinb1c, Mmus\Serpina1e, Mmus\Serpinb9g, Mmus\Serpina16, Mmus\Serpinb9d, Mmus\Serpinb3d, Mmus\Serpinb9c, Mmus\Serpina6, Mmus\Gm11397, Mmus\Serpina5, Mmus\Serpine3, Mmus\Serpina7, Mmus\Serpina3j, Mmus\Serpinb6e, Mmus\Serpina3n, Mmus\Serpinb9f, Mmus\Serpinb3a, Mmus\Serpinb12, Mmus\Serpina1c, Mmus\Serpinc1, Mmus\Serpinb1a, Mmus\Serpinb8, Mmus\Serpina11, Mmus\Serpinb6c, Mmus\Serpinb6b, Mmus\Serpina9, Mmus\Serpinb9, Mmus\Serpina3g, Mmus\Serpinb1b, Mmus\Serpina1d, Mmus\Serpinb11, Mmus\Serpinb9b, Mmus\Serpinh1, Mmus\Serpinb5, Mmus\Serpinb3c, Mmus\Serpina3f, Mmus\Serpinb9e, Mmus\Serpina1a, Mmus\Serpina3a, Mmus\Serpinb13, Mmus\Serpina3c, Mmus\Serpinb10, Mmus\Serping1, Mmus\Serpina3i" "Hsap\SERPINB2, Hsap\SERPINA11, Hsap\SERPINA3, Hsap\SERPINA1, Hsap\SERPINC1, Hsap\SERPINA9, Hsap\SERPINB13, Hsap\SERPINB11, Hsap\SERPINB4, Hsap\SERPINA12, Hsap\SERPINA7, Hsap\SERPINI1, Hsap\SERPINB1, Hsap\SERPINE3, Hsap\SERPINB8, Hsap\SERPINA10, Hsap\SERPINA6, Hsap\SERPINB9, Hsap\SERPINE2, Hsap\HMSD, Hsap\SERPINA5, Hsap\SERPINB5, Hsap\SERPINB10, Hsap\SERPINH1, Hsap\SERPINB7, Hsap\SERPINB6, Hsap\SERPINI2, Hsap\SERPING1, Hsap\SERPINB3, Hsap\SERPINB12, Hsap\SERPINA4, Hsap\SERPIND1, Hsap\SERPINE1" FBgn0264715 CR43983 - http://flybase.org/reports/FBgn0264715 non_protein_coding_gene - - - CR43983 - CR43983 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261507 CG42655 - http://flybase.org/reports/FBgn0261507 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42655 - CG42655 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050052 Obp49a Odorant-binding protein 49a http://flybase.org/reports/FBgn0050052 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "Obp49a, CG30052, CG8769, BcDNA:GH25962, DmelObp49a, Obp49A, obp49a" IPR006170:Pheromone/general odorant binding protein CG30052 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,viable,visible" "trichogen cell,mesothoracic tergum" FBgn0262607 CG43133 - http://flybase.org/reports/FBgn0262607 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43133 - CG43133 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069992 BG01891 BG01891 http://flybase.org/reports/FBgn0069992 gene - - - BG01891 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0034141 CG8311 - http://flybase.org/reports/FBgn0034141 protein_coding_gene dolichol kinase activity ; GO:0004168 | inferred from biological aspect of ancestor with PANTHER:PTN000324722 dolichol kinase activity ; GO:0004168 | inferred from sequence or structural similarity with SGD:S000004615 dolichyl monophosphate biosynthetic process ; GO:0043048 | inferred from biological aspect of ancestor with PANTHER:PTN000324722 protein glycosylation ; GO:0006486 | inferred from biological aspect of ancestor with PANTHER:PTN000324722 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000324722 CG8311 IPR032974:Polyprenol kinase family CG8311 11-Aug-17 DroID_v2017_08 Drer\dolk "Scer\SEC59, Scer\DGK1" "Cele\srh-167, Cele\Y56A3A.36" Xtro\dolk Mmus\Dolk Hsap\DOLK viable FBgn0032791 CG18094 - http://flybase.org/reports/FBgn0032791 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797" - - "CG10048, CG18094" IPR015797:NUDIX hydrolase domain-like CG18094 11-Aug-17 DroID_v2017_08 Drer\nudt19 - Cele\ndx-7 Xtro\nudt19 Mmus\Nudt19 Hsap\NUDT19 FBgn0012018 tRNA:Tyr-GTA-3-1 transfer RNA:Tyrosine-GTA 3-1 http://flybase.org/reports/FBgn0012018 "FBgn0012014, FBgn0051905" tRNA_gene - - - "Tyr-tRNA, tRNA-Tyr, tRNA:tyr1:28C, tRNA[Tyr][[1gamma]], tRNA:Y, CR31905, tRNA[Tyr], tRNA:TyrGUA, tRNA:Tyr-GTA-3-1, tRNA:Y1:28C, tRNA-Und-NNN-1-1" - CR31905 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004764 l(3)89Da lethal (3) 89Da http://flybase.org/reports/FBgn0004764 - gene - - - l(3)89Da - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266011 CR44784 - http://flybase.org/reports/FBgn0266011 non_protein_coding_gene - - - CR44784 - CR44784 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013939 E(sina)4 Enhancer of seven in absentia 4 http://flybase.org/reports/FBgn0013939 - gene - - - E(sina)4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "photoreceptor cell R7,secondary pigment cell" FBgn0265373 CG44314 - http://flybase.org/reports/FBgn0265373 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44314 - CG44314 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264078 Flo2 Flotillin 2 http://flybase.org/reports/FBgn0264078 protein_coding_gene structural molecule activity ; GO:0005198 | non-traceable author statement cell adhesion ; GO:0007155 | non-traceable author statement melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay flotillin complex ; GO:0016600 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG32593, FLO2, CG14409, CG11547, FLO[Dm]-2, DmFlo2, reggie-1, Flo-2, Flo2, flo2, Flo, mdcds_54791" "IPR001107:Band 7 domain, IPR027705:Flotillin family, IPR031905:Flotillin, C-terminal domain" CG32593 11-Aug-17 DroID_v2017_08 "Drer\flot1a, Drer\flot2a, Drer\flot1b, Drer\flot2b" - - "Xtro\flot1, Xtro\flot2" "Mmus\Flot2, Mmus\Flot1" "Hsap\FLOT1, Hsap\FLOT2" FBgn0085782 CR41101 - http://flybase.org/reports/FBgn0085782 non_protein_coding_gene - - - CR41101 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013460 fs(3)302 fs(3)302 http://flybase.org/reports/FBgn0013460 - gene - - - fs(3)302 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,female sterile,male sterile" FBgn0020348 anon-46Fa anon-46Fa http://flybase.org/reports/FBgn0020348 - gene - - - "6H8, anon-46Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069932 CG41119 - http://flybase.org/reports/FBgn0069932 protein_coding_gene - - - CG41119 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283428 CR46271 - http://flybase.org/reports/FBgn0283428 non_protein_coding_gene - - - CR46271 - CR46271 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060913 l(3)S042805b lethal (3) S042805b http://flybase.org/reports/FBgn0060913 gene - - - "0428/05, l(3)S042805b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0058374 CG40374 - http://flybase.org/reports/FBgn0058374 protein_coding_gene - - - CG40374 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030006 CG17982 - http://flybase.org/reports/FBgn0030006 protein_coding_gene - - - CG17982 - CG17982 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003156 pt platinum http://flybase.org/reports/FBgn0003156 - gene - - - "l(1)VA70, pa, fs(1)M47, l(1)7Fb, pt" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female sterile,rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,male sterile,male,poor,body color defective" "egg,macrochaeta" FBgn0011573 Cdc37 Cdc37 http://flybase.org/reports/FBgn0011573 FBgn0004640 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR013855 protein tyrosine kinase activator activity ; GO:0030296 | non-traceable author statement heat shock protein binding ; GO:0031072 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 chaperone binding ; GO:0051087 | non-traceable author statement intracellular signal transduction ; GO:0035556 | non-traceable author statement protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D protein stabilization ; GO:0050821 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q16543 "cdc37, DROCPDR, CPDR-2, CPDR-1, E(sev)3B, CG12019, Cdc37" "IPR004918:Cdc37, IPR013855:Cdc37, N-terminal domain, IPR013873:Cdc37, C-terminal, IPR013874:Cdc37, Hsp90 binding" CG12019 11-Aug-17 DroID_v2017_08 "Drer\cdc37, Drer\cdc37l1" Scer\CDC37 "Cele\K07E8.6, Cele\cdc-37" "Xtro\cdc37l1, Xtro\cdc37" "Mmus\Cdc37l1, Mmus\Cdc37" "Hsap\CDC37, Hsap\CDC37L1" " embryonic stage | early , larval stage | third instar , embryonic stage | late " eye-antennal disc

"cell polarity defective,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,wild-type,lethal,recessive,meiotic cell cycle defective,cytokinesis defective,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,increased cell size,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere,somatic clone,eye photoreceptor cell,ommatidium,rhabdomere, with Df(3L)MY10,adult abdomen,spermatid,spindle,anaphase & condensed nuclear chromosome,actomyosin contractile ring,nucleus,mitosis & nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell" DRSC08648 K 1.321519302 -0.414487054 0.296851587 0.138160272 -0.27233522 2.459577781 FBgn0015984 l(2)PC4-M lethal (2) PC4-M http://flybase.org/reports/FBgn0015984 - gene - - - "l(2)PC4-E, l(2)PC4-M" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030260 CG1537 - http://flybase.org/reports/FBgn0030260 protein_coding_gene - - - "BcDNA:GH02938, CG1537" - CG1537 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052702 Cubn Cubilin http://flybase.org/reports/FBgn0052702 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" renal protein absorption ; GO:0097017 | inferred from mutant phenotype nephrocyte filtration ; GO:0097206 | inferred from mutant phenotype - "tok-like, CT7882, CG2996, CG32702, Cubn, dCubn" "IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR000859:CUB domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR009030:Growth factor receptor cysteine-rich domain, IPR018097:EGF-like calcium-binding, conserved site" CG32702 11-Aug-17 DroID_v2017_08 "Drer\tll1, Drer\mep1a.1, Drer\pcolce2b, Drer\he1a, Drer\LOC100003133, Drer\LOC797085, Drer\bmp1a, Drer\mep1b, Drer\c6ast4, Drer\tnfaip6, Drer\csmd2, Drer\he1b, Drer\pcolce2a, Drer\nrp1a, Drer\npsn, Drer\c6ast3, Drer\he2, Drer\bmp1b, Drer\nrp1b, Drer\c6ast1, Drer\mep1a.2, Drer\si:ch73-40a17.3, Drer\nrp2b, Drer\cubn" - "Cele\ZC116.3, Cele\nas-12, Cele\nas-7, Cele\nas-39, Cele\nas-13, Cele\nas-6, Cele\nas-14, Cele\nas-4, Cele\nas-15, Cele\nas-2, Cele\Y19D10A.6, Cele\nas-8, Cele\nas-1" "Xtro\tll1, Xtro\bmp1, Xtro\mep1b, Xtro\accs, Xtro\mep1a, Xtro\svep1, Xtro\tnfaip6, Xtro\LOC100489456, Xtro\LOC100492324, Xtro\uvs.2, Xtro\tll2, Xtro\cubn" "Mmus\Tll2, Mmus\Csmd1, Mmus\Adgrg6, Mmus\Bmp1, Mmus\Astl, Mmus\Tnfaip6, Mmus\Nrp2, Mmus\Pcolce, Mmus\Tll1, Mmus\Csmd2, Mmus\Csmd3, Mmus\Mep1b, Mmus\Svep1, Mmus\Nrp1, Mmus\Pcolce2, Mmus\Mep1a, Mmus\Cubn" "Hsap\CUBN, Hsap\NRP2, Hsap\NRP1, Hsap\MEP1B, Hsap\MEP1A, Hsap\TLL1, Hsap\SCUBE1, Hsap\ADGRG6, Hsap\BMP1, Hsap\PCOLCE, Hsap\CR1, Hsap\CSMD2, Hsap\CSMD3, Hsap\SVEP1, Hsap\TNFAIP6, Hsap\SCUBE2, Hsap\PCOLCE2, Hsap\CSMD1, Hsap\ASTL, Hsap\TLL2" "viable,chemical sensitive" embryonic/larval pericardial cell FBgn0002238 l(3)68Be lethal (3) 68Be http://flybase.org/reports/FBgn0002238 FBgn0002232 gene - - - "l(3)C28, C, l(3)C, l(3)68Be" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0030587 CG9522 - http://flybase.org/reports/FBgn0030587 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG9522, Dm GMCiota1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9522 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0034793 asrij asrij http://flybase.org/reports/FBgn0034793 protein_coding_gene - regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype lymph gland development ; GO:0048542 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype embryonic hemopoiesis ; GO:0035162 | inferred from expression pattern inferred from mutant phenotype cytoplasmic vesicle ; GO:0031410 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "Dmasrij, CG13533, asrij, arj, Asrij, FBgn 34793" IPR009764:Ovarian carcinoma immunoreactive antigen CG13533 11-Aug-17 DroID_v2017_08 "Drer\ociad2, Drer\LOC553528, Drer\ociad1" - - "Xtro\ociad2, Xtro\ociad1" "Mmus\Ociad1, Mmus\Ociad2" "Hsap\OCIAD2, Hsap\OCIAD1" "developmental rate defective,viable,fertile,mitotic cell cycle defective" "secondary lobe of embryonic/larval lymph gland,ectopic | third instar larval stage,plasmatocyte,ectopic,embryonic/larval hemocyte,medullary zone of lymph gland primary lobe" DRSC04175 E -0.547016561 -0.662511057 -1.547508917 0.615120558 -0.020152039 -0.898850601 FBgn0030975 SdhBL "Succinate dehydrogenase, subunit B (iron-sulfur)-like" http://flybase.org/reports/FBgn0030975 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR004489 electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001041, InterPro:IPR025192 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR006058" "tricarboxylic acid cycle ; GO:0006099 | inferred from electronic annotation with InterPro:IPR004489 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000229864 respiratory electron transport chain ; GO:0022904 | inferred from biological aspect of ancestor with PANTHER:PTN000229864 mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from sequence or structural similarity with SdhB" mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000229867 "CG7349, DHSB, SdhBL" "IPR025192:Succinate dehydogenase/fumarate reductase N-terminal, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR004489:Succinate dehydrogenase/fumarate reductase iron-sulphur protein, IPR006058:2Fe-2S ferredoxin, iron-sulphur binding site, IPR009051:Alpha-helical ferredoxin, IPR012675:Beta-grasp domain, IPR017896:4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR017900:4Fe-4S ferredoxin, iron-sulphur binding, conserved site" CG7349 11-Aug-17 DroID_v2017_08 Drer\sdhb Scer\SDH2 Cele\sdhb-1 Xtro\sdhb Mmus\Sdhb Hsap\SDHB FBgn0066355 l(3)51 lethal (3) 51 http://flybase.org/reports/FBgn0066355 gene - - - l(3)51 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267766 CR46097 - http://flybase.org/reports/FBgn0267766 non_protein_coding_gene - - - CR46097 - CR46097 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085452 CG34423 - http://flybase.org/reports/FBgn0085452 protein_coding_gene ATPase inhibitor activity ; GO:0042030 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 negative regulation of ATPase activity ; GO:0032780 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000601269 "CG34423, anon-WO0118547.139, CG11079" IPR007648:Mitochondrial ATPase inhibitor CG34423 11-Aug-17 DroID_v2017_08 "Drer\atpif1b, Drer\atpif1a" - "Cele\mai-2, Cele\mai-1" Xtro\atpif1 Mmus\Atpif1 Hsap\ATPIF1 FBgn0036584 CG13054 - http://flybase.org/reports/FBgn0036584 protein_coding_gene - - - CG13054 IPR032050:Domain of unknown function DUF4797 CG13054 11-Aug-17 DroID_v2017_08 - - - - - - DRSC29594 K -0.640629146 -0.691996366 0.287765517 -0.32164358 1.72270192 0.714228883 FBgn0030038 CG1440 - http://flybase.org/reports/FBgn0030038 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from electronic annotation with InterPro:IPR004134 cysteine-type peptidase activity ; GO:0008234 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR004134 response to toxic substance ; GO:0009636 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 homocysteine catabolic process ; GO:0043418 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 cytosol ; GO:0005829 | inferred from direct assay CG1440 "IPR000169:Cysteine peptidase, cysteine active site, IPR004134:Peptidase C1B, bleomycin hydrolase" CG1440 11-Aug-17 DroID_v2017_08 Drer\blmh Scer\LAP3 - Xtro\blmh Mmus\Blmh Hsap\BLMH viable FBgn0051004 mesh mesh http://flybase.org/reports/FBgn0051004 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VW87 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O46101 cell-matrix adhesion ; GO:0007160 | inferred from electronic annotation with InterPro:IPR003886 smooth septate junction assembly ; GO:0090528 | inferred from mutant phenotype smooth septate junction ; GO:0005920 | inferred from direct assay "CG31004, CG15560, CT5150, CG12074, anon-WO0140519.233, mesh, Mesh" "IPR000436:Sushi/SCR/CCP domain, IPR001846:von Willebrand factor, type D domain, IPR003886:NIDO domain, IPR005533:AMOP domain, IPR014756:Immunoglobulin E-set, IPR013783:Immunoglobulin-like fold" CG31004 11-Aug-17 DroID_v2017_08 "Drer\LOC101882496, Drer\im:7156467, Drer\tecta, Drer\LOC100148750, Drer\sned1, Drer\si:ch73-329n5.6, Drer\adgrf6, Drer\si:ch73-105b23.6, Drer\zgc:112964" - "Cele\K03H1.5, Cele\R09E10.5, Cele\F54D1.6" Xtro\tecta.1 "Mmus\Adgrl4, Mmus\Sned1, Mmus\Susd2, Mmus\Tecta" "Hsap\MUC4, Hsap\SUSD2, Hsap\SNED1, Hsap\TECTA" "lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,some die during pupal stage" "smooth septate junction | first instar larval stageExel6218),embryonic/larval midgut" FBgn0030390 CG15731 - http://flybase.org/reports/FBgn0030390 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15731 IPR031903:Domain of unknown function DUF4766 CG15731 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0027290 l(1)G0161 lethal (1) G0161 http://flybase.org/reports/FBgn0027290 - gene - - - l(1)G0161 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female,recessive" FBgn0267065 CR45509 - http://flybase.org/reports/FBgn0267065 non_protein_coding_gene - - - CR45509 - CR45509 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043846 412\ORF4 412 element ORF4 http://flybase.org/reports/FBgn0043846 transposable_element_gene - - - "412\ORF4, ORF4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085494 Mst77Y-16Psi Male-specific pseudogene 77Y 16 http://flybase.org/reports/FBgn0085494 pseudogene_attribute - - - "Mst77Y-16Psi, CG40530" - CR40530 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039630 CG11843 - http://flybase.org/reports/FBgn0039630 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP43, CG11843" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11843 11-Aug-17 DroID_v2017_08 Drer\masp2 - "Cele\try-3, Cele\try-1, Cele\svh-1" - "Mmus\Plat, Mmus\Plau, Mmus\Habp2, Mmus\Prss12, Mmus\F12, Mmus\Hgfac" - "viable,fertile" FBgn0027935 vu vesuvio http://flybase.org/reports/FBgn0027935 gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available vu - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266309 CR44974 - http://flybase.org/reports/FBgn0266309 non_protein_coding_gene - - - CR44974 - CR44974 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005514 l(2)25Ea lethal (2) 25Ea http://flybase.org/reports/FBgn0005514 - gene - - - "jf25, l(2)gdh-11, l(2)jf25, l(2)gdh11, l(2)25Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033551 CG7222 - http://flybase.org/reports/FBgn0033551 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7222 IPR008580:PPPDE putative peptidase domain CG7222 11-Aug-17 DroID_v2017_08 "Drer\desi1a, Drer\desi2, Drer\LOC794838, Drer\desi1b" - Cele\F36D4.5 "Xtro\desi1, Xtro\desi2" "Mmus\Desi2, Mmus\Desi1" "Hsap\DESI2, Hsap\DESI1" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0015975 l(2)PC4-A lethal (2) PC4-A http://flybase.org/reports/FBgn0015975 - gene - - - l(2)PC4-A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039958 CG12567 - http://flybase.org/reports/FBgn0039958 protein_coding_gene 8-oxo-dGDP phosphatase activity ; GO:0044715 | inferred from biological aspect of ancestor with PANTHER:PTN000341541 - - CG12567 "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like, IPR031804:Domain of unknown function DUF4743" CG12567 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-6n6.2, Drer\tpk1" "Scer\THI80, Scer\YJR142W" Cele\tpk-1 - Mmus\Tpk1 Hsap\TPK1 FBgn0028180 l(3)S024535b lethal (3) S024535b http://flybase.org/reports/FBgn0028180 gene - - - "88A, 0245/35, l(3)S024535, l(3)S024535b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030041 CG12116 - http://flybase.org/reports/FBgn0030041 protein_coding_gene - - - "CG12116, 144701_at" "IPR016040:NAD(P)-binding domain, IPR002347:Short-chain dehydrogenase/reductase SDR" CG12116 11-Aug-17 DroID_v2017_08 "Drer\spra, Drer\sprb" "Scer\YIR035C, Scer\IRC24" "Cele\C01G12.5, Cele\F02C12.2" - Mmus\Spr Hsap\SPR viable FBgn0051516 CG31516 - http://flybase.org/reports/FBgn0051516 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE68446, CG31516" IPR031941:Domain of unknown function DUF4773 CG31516 11-Aug-17 DroID_v2017_08 - - Cele\C09D4.2 - - - viable FBgn0046325 ms(2)38DEa ms(2)38DEa http://flybase.org/reports/FBgn0046325 gene - - - "ms in 38D/E, ms(2)38DEa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060871 l(3)S047003 lethal (3) S047003 http://flybase.org/reports/FBgn0060871 gene - - - "0470/03, l(3)S047003" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0027181 l(2)60A-M lethal (2) 60A-M http://flybase.org/reports/FBgn0027181 - gene - - - l(2)60A-M - - 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,lethal,recessive" FBgn0005006 dfi deformed eye http://flybase.org/reports/FBgn0005006 - gene - - - dfi - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male,poor,female sterile,recessive" eye FBgn0034634 CG10494 - http://flybase.org/reports/FBgn0034634 protein_coding_gene - - - CG10494 - CG10494 11-Aug-17 DroID_v2017_08 Drer\zgc:113263 - - - Mmus\Msantd2 Hsap\MSANTD2 "partially lethal - majority die,some die during pupal stage" FBgn0069127 mei(3)M20 mei(3)M20 http://flybase.org/reports/FBgn0069127 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(3)M20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,female semi-sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0265884 CR44673 - http://flybase.org/reports/FBgn0265884 non_protein_coding_gene - - - CR44673 - CR44673 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265868 CR44657 - http://flybase.org/reports/FBgn0265868 non_protein_coding_gene - - - "lincRNA.993, CR44657" - CR44657 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030278 CG15200 - http://flybase.org/reports/FBgn0030278 protein_coding_gene - sperm competition ; GO:0046692 | inferred from mutant phenotype - CG15200 - CG15200 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039197 CG17780 - http://flybase.org/reports/FBgn0039197 protein_coding_gene - - - "CG17780, BcDNA:RE41041" IPR006631:Protein of unknown function DM4/12 CG17780 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025123 su(RpII140[Z36])S5 su(RpII140[Z36])S5 http://flybase.org/reports/FBgn0025123 - gene - - - "Z36[S5], su(RpII140[Z36])S5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004811 fs(2)ltoPP43 female sterile (2) ltoPP43 http://flybase.org/reports/FBgn0004811 "FBgn0026579, FBgn0032823" protein_coding_gene - regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype - "CG10528, l(2)38Ac, LD12957, BEST:LD12957, fs(2)ltoPP43" IPR013883:Transcription factor Iwr1 CG10528 11-Aug-17 DroID_v2017_08 Drer\slc7a6os Scer\IWR1 Cele\W01G7.4 Xtro\slc7a6os Mmus\Slc7a6os Hsap\SLC7A6OS "viable,fertile,lethal,recessive,visible,wild-type,long lived,female sterile" "eye,trichogen cell,mesothoracic tergum" FBgn0267469 CR45819 - http://flybase.org/reports/FBgn0267469 non_protein_coding_gene - - - CR45819 - CR45819 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259925 p150 - http://flybase.org/reports/FBgn0259925 protein_coding_gene - - - p150 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067659 sbg strindberg http://flybase.org/reports/FBgn0067659 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sbg - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0267425 CR45778 - http://flybase.org/reports/FBgn0267425 non_protein_coding_gene - - - "CR45778, Mgn99994" - CR45778 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026384 Or59a Odorant receptor 59a http://flybase.org/reports/FBgn0026384 - protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from sequence or structural similarity with Or85e odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred from sequence or structural similarity with Or85e integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | non-traceable author statement dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "59a, DOR46, CG9820, AN6, 59D.1, dor46, DOR59D.1, Or59D.1, Or46, Or59a" "IPR004117:Olfactory receptor, insect" CG9820 11-Aug-17 DroID_v2017_08 - - - - - - adult stage sensory neuron &&of antennal segment 3

smell perception defective FBgn0033942 Cpr51A Cuticular protein 51A http://flybase.org/reports/FBgn0033942 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr51A, CG10112" IPR000618:Insect cuticle protein CG10112 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003511 Sry-beta Serendipity beta http://flybase.org/reports/FBgn0003511 - protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay "srybeta, sry beta, sry, Sry-beta, sryb, sry-b, Srybeta, sry-beta, CG7938, ser" IPR013087:Zinc finger C2H2-type CG7938 11-Aug-17 DroID_v2017_08 "Drer\znf1078, Drer\si:dkeyp-113d7.1, Drer\znf1136, Drer\znf1070, Drer\drl, Drer\si:dkey-261j4.5, Drer\si:dkey-261j4.4, Drer\si:dkey-253d23.8, Drer\LOC108183935, Drer\zgc:174646, Drer\zgc:113209, Drer\LOC100537687, Drer\znf1051, Drer\znf1041, Drer\zgc:171551, Drer\znf1069, Drer\zgc:173714, Drer\si:ch73-367f21.6, Drer\znf1007, Drer\si:dkey-237m9.1, Drer\si:dkey-261j4.3, Drer\LOC100151333, Drer\znf1059, Drer\im:7141269" Scer\ZAP1 "Cele\klu-1, Cele\Y37E11B.1, Cele\sdz-12" - "Mmus\Zfp930, Mmus\Zfp873, Mmus\Zfp7, Mmus\Gm6710, Mmus\Zfp712, Mmus\Zfp157, Mmus\Zfp182, Mmus\Zbtb41, Mmus\Zfp26, Mmus\Zfp266, Mmus\Zfp37, Mmus\Zkscan8, Mmus\Zfp846, Mmus\Zfp661, Mmus\Zfp2, Mmus\Zkscan7, Mmus\Zfp689" "Hsap\ZNF717, Hsap\ZFP37, Hsap\ZNF689, Hsap\ZNF121, Hsap\ZNF510, Hsap\ZNF470, Hsap\ZNF808, Hsap\ZNF577, Hsap\ZNF561, Hsap\ZNF658, Hsap\ZNF576, Hsap\ZNF506, Hsap\ZFP69B, Hsap\ZNF555, Hsap\ZNF582, Hsap\ZNF679, Hsap\ZNF599, Hsap\ZNF2, Hsap\ZNF449, Hsap\ZBTB41, Hsap\ZNF300, Hsap\ZFP28, Hsap\ZNF630, Hsap\ZNF420, Hsap\ZNF70, Hsap\ZNF30, Hsap\ZNF182, Hsap\ZFP2, Hsap\ZNF268, Hsap\ZKSCAN7, Hsap\GZF1" embryonic stage -- adult stage "partially lethal - majority die,some die during pupal stage" FBgn0264419 FCO-D - http://flybase.org/reports/FBgn0264419 gene - - - FCO-D - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0060347 l(3)S143206 lethal (3) S143206 http://flybase.org/reports/FBgn0060347 gene - - - "1432/06, l(3)S143206" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065635 l(2)SH0770 lethal (2) SH0770 http://flybase.org/reports/FBgn0065635 gene - - - "l(2)SH0770, l(2)SH2 0770" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267479 CR45829 - http://flybase.org/reports/FBgn0267479 non_protein_coding_gene - - - CR45829 - CR45829 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030801 Rcp Receptor component protein http://flybase.org/reports/FBgn0030801 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR010997 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000399700 positive regulation of G-protein coupled receptor protein signaling pathway ; GO:0045745 | inferred from direct assay transcription initiation from RNA polymerase III promoter ; GO:0006384 | inferred from biological aspect of ancestor with PANTHER:PTN000399700 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000399700 "CG4875, Rcp, dRCP" "IPR006590:RNA polymerase II, Rpb4, core, IPR010997:HRDC-like, IPR005574:RNA polymerase II, Rpb4" CG4875 11-Aug-17 DroID_v2017_08 Drer\crcp Scer\RPC17 Cele\M106.7 Xtro\crcp "Mmus\Polr2d, Mmus\Crcp" "Hsap\POLR2D, Hsap\CRCP, Hsap\ASL" "visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" mesothoracic tergum FBgn0037842 CG6567 - http://flybase.org/reports/FBgn0037842 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 palmitoyl-(protein) hydrolase activity ; GO:0008474 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 protein depalmitoylation ; GO:0002084 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 CG6567 "IPR003140:Phospholipase/carboxylesterase/thioesterase, IPR029058:Alpha/Beta hydrolase fold" CG6567 11-Aug-17 DroID_v2017_08 "Drer\lyplal1, Drer\lypla2" Scer\YLR118C Cele\F01D5.8 "Xtro\lyplal1, Xtro\lypla1, Xtro\lypla2" "Mmus\Lypla1, Mmus\Lyplal1, Mmus\Lypla2" "Hsap\LYPLAL1, Hsap\LYPLA2, Hsap\LYPLA1" "viable,fertile" FBgn0060631 l(3)S085505 lethal (3) S085505 http://flybase.org/reports/FBgn0060631 gene - - - "0855/05, l(3)S085505" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0001658 l(1)ds12 lethal (1) discs small 12 http://flybase.org/reports/FBgn0001658 - gene - - - "l(1)1-45, l(1)ds12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,ring gland" FBgn0065707 l(2)SH0610 lethal (2) SH0610 http://flybase.org/reports/FBgn0065707 gene - - - "l(2)SH0610, l(2)SH2 0610" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039667 CG2010 - http://flybase.org/reports/FBgn0039667 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG2010, FBXL3" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG2010 11-Aug-17 DroID_v2017_08 Drer\si:ch211-214j8.12 - Cele\T28B4.1 - - - FBgn0031635 tank tank http://flybase.org/reports/FBgn0031635 protein_coding_gene - macroautophagy ; GO:0016236 | inferred from biological aspect of ancestor with PANTHER:PTN000483471 apoptotic process ; GO:0006915 | inferred from biological aspect of ancestor with PANTHER:PTN000483472 positive regulation of response to ethanol ; GO:1901418 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000483471 "CG15626, tank" IPR009890:Etoposide-induced 2.4 CG15626 11-Aug-17 DroID_v2017_08 Drer\ei24 - Cele\epg-4 Xtro\ei24 Mmus\Ei24 Hsap\EI24 "chemical resistant,partially lethal - majority die,some die during pupal stage,lethal" FBgn0013257 E(var)3118 E(var)3118 http://flybase.org/reports/FBgn0013257 - gene - - - E(var)3118 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0024866 l(3)04679 lethal (3) 04679 http://flybase.org/reports/FBgn0024866 - gene - - - "4679, l(3)04679" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011229 pto pistachio http://flybase.org/reports/FBgn0011229 - gene molecular_function ; GO:0003674 | no biological data available spermatid development ; GO:0007286 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available pto - - 11-Aug-17 DroID_v2017_08 - - - - - - male semi-sterile FBgn0060336 l(3)S144607a lethal (3) S144607a http://flybase.org/reports/FBgn0060336 gene - - - "1446/07, l(3)S144607a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040950 Muc26B Mucin 26B http://flybase.org/reports/FBgn0040950 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:RE30702, Muc26B, CG13990" IPR002557:Chitin binding domain CG13990 11-Aug-17 DroID_v2017_08 - - Cele\Y5H2A.4 - - Hsap\KRTAP10-4 viable DRSC02322 E -0.818958477 0.202858201 1.850548973 0.333261046 0.470494197 -0.84474961 FBgn0005353 su(B)2 suppressor of Bar on 2 http://flybase.org/reports/FBgn0005353 - gene - - - su(B)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028358 l(1)G0151 lethal (1) G0151 http://flybase.org/reports/FBgn0028358 gene - - - l(1)G0151 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" chaeta FBgn0002889 mus203 mutagen-sensitive 203 http://flybase.org/reports/FBgn0002889 - gene - - - mus203 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,radiation sensitive" FBgn0011160 l(1)Q238 lethal (1) Q238 http://flybase.org/reports/FBgn0011160 FBgn0010210 gene - - - l(1)Q238 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265659 CR44466 - http://flybase.org/reports/FBgn0265659 non_protein_coding_gene - - - "lincRNA.328, CR44466" - CR44466 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052785 tRNA:Gln-CTG-2-1 transfer RNA:Glutamine-CTG 2-1 http://flybase.org/reports/FBgn0052785 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002566.trna1-GlnCTG, tRNA:Q:CTG:AE002566, CR32785, chrX.trna1-GlnCTG, tRNA:Gln-CTG-2-1, tRNA:CR32785, tRNA-Gln-CTG-2-1, CAG" - CR32785 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039857 RpL6 Ribosomal protein L6 http://flybase.org/reports/FBgn0039857 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000915, InterPro:IPR005568 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000076315 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 centrosome organization ; GO:0051297 | inferred from mutant phenotype" ribosome ; GO:0005840 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "CG11522, RpL6, Rp L6, RPL6, rpl6" "IPR000915:60S ribosomal protein L6E, IPR005568:Ribosomal protein L6, N-terminal, IPR008991:Translation protein SH3-like domain, IPR014722:Ribosomal protein L2 domain 2" CG11522 11-Aug-17 DroID_v2017_08 Drer\rpl6 "Scer\RPL6A, Scer\RPL6B" Cele\rpl-6 Xtro\rpl6 Mmus\Rpl6 Hsap\RPL6 DRSC14323 IEK 4.084981903 -1.009584704 2.967252844 -3.457939169 0.733726893 4.0728822 FBgn0005189 l(2)S45 lethal of Seto 45 http://flybase.org/reports/FBgn0005189 - gene - - - l(2)S45 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" leg FBgn0062684 EP1555 EP1555 http://flybase.org/reports/FBgn0062684 gene - - - "EP(X)1555, EP1555" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262279 mir-983-2 mir-983-2 stem loop http://flybase.org/reports/FBgn0262279 miRNA_gene - - - "mir-983-2, miR-983-2, 983-2, CR42986, miR-983" - CR42986 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing FBgn0032096 Or30a Odorant receptor 30a http://flybase.org/reports/FBgn0032096 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "30a, DOR56, 30A.1, CG13106, Or30a" "IPR004117:Olfactory receptor, insect" CG13106 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,viable" FBgn0033400 CG2063 - http://flybase.org/reports/FBgn0033400 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR012479 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG2063 IPR012479:SAP30-binding protein CG2063 11-Aug-17 DroID_v2017_08 Drer\sap30bp - Cele\Y67D2.7 Xtro\sap30bp Mmus\Sap30bp Hsap\SAP30BP "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC06811 K 0.074324906 1.070768493 -0.041174307 0.753273232 -1.502907091 -1.19622964 FBgn0263998 Ack-like Activated Cdc42 kinase-like http://flybase.org/reports/FBgn0263998 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357" regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein phosphorylation ; GO:0006468 | non-traceable author statement autophagic cell death ; GO:0048102 | inferred from expression pattern protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern cell migration ; GO:0016477 | inferred from biological aspect of ancestor with PANTHER:PTN001231165 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 "PR2, CG43741, CG3969, DPR2, PR2/ACK, DmHD-11, DRODPR2, dACK, Rp2, HD-11, CG33007, Ack-like" "IPR011511:Variant SH3 domain, IPR017441:Protein kinase, ATP binding site, IPR011009:Protein kinase-like domain, IPR001452:SH3 domain, IPR000719:Protein kinase domain, IPR000095:CRIB domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR008266:Tyrosine-protein kinase, active site, IPR020635:Tyrosine-protein kinase, catalytic domain" CG43741 11-Aug-17 DroID_v2017_08 "Drer\syk, Drer\zap70, Drer\LOC100148041, Drer\tnk2b" - "Cele\ark-1, Cele\kin-32" "Xtro\syk, Xtro\zap70, Xtro\tnk2" "Mmus\Tnk1, Mmus\Tnk2, Mmus\Zap70, Mmus\Syk" "Hsap\TNK2, Hsap\SYK, Hsap\ZAP70, Hsap\TNK1" FBgn0034509 Obp57c Odorant-binding protein 57c http://flybase.org/reports/FBgn0034509 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 transport ; GO:0006810 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "CG13421, Obp57a, 57c, BcDNA:RH68952, Obp57c, DmelObp57c, obp57c" IPR006170:Pheromone/general odorant binding protein CG13421 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040647 CG10987 - http://flybase.org/reports/FBgn0040647 protein_coding_gene - - - CG10987 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262272 mir-1002 mir-1002 stem loop http://flybase.org/reports/FBgn0262272 miRNA_gene - - - "mir-1002, 1002, miR-1002, CR42979, dme-miR-1002-5p" - CR42979 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263468 snoRNA:SC35-a - http://flybase.org/reports/FBgn0263468 snoRNA_gene - - - "snoRNA:SC35-a, snoHACA_01" - CR43583 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010334 X81 X81 http://flybase.org/reports/FBgn0010334 - gene - - - X81 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264348 CR43804 - http://flybase.org/reports/FBgn0264348 non_protein_coding_gene - - - CR43804 - CR43804 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265633 CR44440 - http://flybase.org/reports/FBgn0265633 non_protein_coding_gene - - - "CR44440, lincRNA.918" - CR44440 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266046 CR44811 - http://flybase.org/reports/FBgn0266046 non_protein_coding_gene - - - CR44811 - CR44811 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065746 l(2)SH0516 lethal (2) SH0516 http://flybase.org/reports/FBgn0065746 gene - - - "l(2)SH0516, l(2)SH2 0516" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028427 Ilk Integrin linked kinase http://flybase.org/reports/FBgn0028427 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein kinase activity ; GO:0004672 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with wech muscle attachment ; GO:0016203 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | NOT inferred from key residues cell-matrix adhesion ; GO:0007160 | inferred from mutant phenotype integrin-mediated signaling pathway ; GO:0007229 | inferred from biological aspect of ancestor with PANTHER:PTN001510364 substrate adhesion-dependent cell spreading ; GO:0034446 | inferred from biological aspect of ancestor with PANTHER:PTN001510364 cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | non-traceable author statement cell adhesion ; GO:0007155 | traceable author statement apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000584061 focal adhesion ; GO:0005925 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from sequence or structural similarity stress fiber ; GO:0001725 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001510364 "ILK, ilk, CG10504, CT29478, DmILK, l(3)78Ca, Ilk" "IPR000719:Protein kinase domain, IPR002110:Ankyrin repeat, IPR011009:Protein kinase-like domain, IPR020683:Ankyrin repeat-containing domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG10504 11-Aug-17 DroID_v2017_08 Drer\ilk Scer\YGL242C "Cele\pat-4, Cele\F57B9.8, Cele\ZK622.1, Cele\kin-26" Xtro\ilk Mmus\Ilk Hsap\ILK "wild-type,lethal,visible,recessive,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of first instar larval stage,viable" "embryonic/larval somatic muscle,wing,somatic clone,muscle fiber,heat sensitive" FBgn0085732 CR40190 - http://flybase.org/reports/FBgn0085732 pseudogene_attribute - - - CR40190 - CR40190 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026637 l(2)k13910 lethal (2) k13910 http://flybase.org/reports/FBgn0026637 - gene - - - l(2)k13910 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038678 mRpL55 mitochondrial ribosomal protein L55 http://flybase.org/reports/FBgn0038678 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P0C2B8 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with protein_id:BAB28535 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P0C2B8 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:P0C2B8 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with protein_id:BAB28535 mitochondrion ; GO:0005739 | inferred from direct assay "tmb, CG14283, MRP-L55, BcDNA:RH10246, mRpL55" "IPR018615:Ribosomal protein L55, mitochondrial" CG14283 11-Aug-17 DroID_v2017_08 Drer\zgc:171480 - Cele\mrpl-55 - Mmus\Mrpl55 Hsap\MRPL55 "developmental rate defective,female sterile,germline clone,cell lethal,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal,viable,fertile,visible" "actin filament | somatic cloneGMR.PU, cdiR47,trichogen cell" FBgn0264434 CR43852 - http://flybase.org/reports/FBgn0264434 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR43852 - CR43852 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036028 CG16717 - http://flybase.org/reports/FBgn0036028 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843 - - CG16717 "IPR024201:Calcineurin-like phosphoesterase, IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR029052:Metallo-dependent phosphatase-like" CG16717 11-Aug-17 DroID_v2017_08 "Drer\mpped2, Drer\mpped1, Drer\mpped2a" - "Cele\T07D4.2, Cele\C25E10.12, Cele\K07C11.7" Xtro\mpped2 "Mmus\Mpped2, Mmus\Mpped1" "Hsap\MPPED1, Hsap\MPPED2" viable FBgn0262947 CG43266 - http://flybase.org/reports/FBgn0262947 protein_coding_gene - - - CG43266 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004641 E(sev)3D Enhancer of sevenless 3D http://flybase.org/reports/FBgn0004641 - gene - - - "H214, E(sev)3D" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001359 l(1)1EFh lethal (1) 1EFh http://flybase.org/reports/FBgn0001359 - gene - - - "l(1)BA8, l(1)1EFh" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266753 CR45226 - http://flybase.org/reports/FBgn0266753 non_protein_coding_gene - - - CR45226 - CR45226 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065941 l(2)SH0115 lethal (2) SH0115 http://flybase.org/reports/FBgn0065941 gene - - - "l(2)SH0115, l(2)SH2 0115" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019663 ply paisley http://flybase.org/reports/FBgn0019663 - gene - - - ply - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,cold sensitive" wing hair FBgn0028623 l(2)05095a lethal (2) 05095a http://flybase.org/reports/FBgn0028623 gene - - - "l(2)05095, l(2)05095a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014860 Lcch2 Ligand-gated chloride channel homolog 2 http://flybase.org/reports/FBgn0014860 - gene - - - "LCCH2, Lcch2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267638 CR45976 - http://flybase.org/reports/FBgn0267638 non_protein_coding_gene - - - CR45976 - CR45976 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017429 CG5989 - http://flybase.org/reports/FBgn0017429 - protein_coding_gene ribosome binding ; GO:0043022 | inferred from electronic annotation with InterPro:IPR033122 cellular metal ion homeostasis ; GO:0006875 | inferred from biological aspect of ancestor with PANTHER:PTN000360953 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000360956 "anon-66Db, CG5989" "IPR011685:LETM1-like, IPR003100:PAZ domain, IPR033122:Letm1 ribosome-binding domain" CG5989 11-Aug-17 DroID_v2017_08 Drer\letmd1 "Scer\MDM38, Scer\YLH47" Cele\F30F8.9 Xtro\letmd1 Mmus\Letmd1 Hsap\LETMD1 viable FBgn0065423 l(2)SH1519 lethal (2) SH1519 http://flybase.org/reports/FBgn0065423 gene - - - "l(2)SH1519, l(2)SH2 1519" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051665 wry weary http://flybase.org/reports/FBgn0051665 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 Notch binding ; GO:0005112 | inferred from physical interaction with N" heart process ; GO:0003015 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype cell surface ; GO:0009986 | inferred from direct assay "CT35769, CG15621, CG12704, wry, CG31665" "IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR009030:Growth factor receptor cysteine-rich domain, IPR018097:EGF-like calcium-binding, conserved site" CG31665 11-Aug-17 DroID_v2017_08 "Drer\dner, Drer\si:dkey-163f14.6" - - Xtro\dner "Mmus\Dner, Mmus\Dll3" "Hsap\NOTCH2NL, Hsap\DLL3, Hsap\DNER" viable "adult heart,heat sensitive" DRSC00456 K 0.223670984 0.796397097 0.082206128 0.636242073 -0.640880008 -1.553549396 FBgn0000510 Dt Detached http://flybase.org/reports/FBgn0000510 - gene - - - Dt - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036484 Pex3 Peroxin 3 http://flybase.org/reports/FBgn0036484 protein_coding_gene - peroxisome organization ; GO:0007031 | inferred from mutant phenotype fatty acid elongation ; GO:0030497 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8858 positive regulation of ceramide biosynthetic process ; GO:2000304 | inferred from mutant phenotype integral component of peroxisomal membrane ; GO:0005779 | inferred from electronic annotation with InterPro:IPR006966 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8858 "CG6859, pex3, Pex3, DmelPex3, PEX3" IPR006966:Peroxin-3 CG6859 11-Aug-17 DroID_v2017_08 "Drer\pex3, Drer\runx1" Scer\PEX3 "Cele\rnt-1, Cele\prx-3" "Xtro\pex3, Xtro\runx3" Mmus\Pex3 "Hsap\PEX3, Hsap\RUNX3" "viable,lethal - all die before end of larval stage,recessive,some die during larval stage" peroxisome DRSC10731 K -0.061623959 -0.277858694 0.260979855 1.005999907 2.022460592 0.286486407 FBgn0084764 EP3123 EP3123 http://flybase.org/reports/FBgn0084764 gene - - - EP3123 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036177 CG33268 - http://flybase.org/reports/FBgn0036177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14138, CG33268" - CG33268 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265536 CR44386 - http://flybase.org/reports/FBgn0265536 non_protein_coding_gene - - - "CR44386, lincRNA.331" - CR44386 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036348 CG17687 - http://flybase.org/reports/FBgn0036348 protein_coding_gene - - - CG17687 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG17687 11-Aug-17 DroID_v2017_08 Drer\cfap43 Scer\SMC2 - - Mmus\Cfap43 Hsap\CFAP43 FBgn0036872 CG12519 - http://flybase.org/reports/FBgn0036872 protein_coding_gene - - - CG12519 - CG12519 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029874 CG3342 - http://flybase.org/reports/FBgn0029874 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3342 - CG3342 11-Aug-17 DroID_v2017_08 - - - - - Hsap\FKBP15 "viable,fertile" FBgn0005241 l(3)R88 lethal of Roberts 88 http://flybase.org/reports/FBgn0005241 - gene - - - "l(3)B88, l(3)R88" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0003221 rdp reduplicated http://flybase.org/reports/FBgn0003221 - gene - - - rdp - - 11-Aug-17 DroID_v2017_08 - - - - - - "leg,cold sensitive" FBgn0039765 mRpS18C mitochondrial ribosomal protein S18C http://flybase.org/reports/FBgn0039765 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D5 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D5 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement cytosolic small ribosomal subunit ; GO:0022627 | inferred from biological aspect of ancestor with PANTHER:PTN000336666 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D5 "mRpS18a, CG9688, MRP-S18-(1), mRpS18C" IPR001648:Ribosomal protein S18 CG9688 11-Aug-17 DroID_v2017_08 "Drer\mrps18b, Drer\mrps18c, Drer\mrps18a" Scer\RSM18 "Cele\T14B4.2, Cele\iglr-2" Xtro\mrps18c "Mmus\Mrps18a, Mmus\Mrps18c" "Hsap\MRPS18C, Hsap\MRPS18A" "viable,visible" trichogen cell FBgn0264725 CG43993 - http://flybase.org/reports/FBgn0264725 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43993 - CG43993 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265424 lncRNA:TS14 long noncoding RNA: testis-specific 14 http://flybase.org/reports/FBgn0265424 non_protein_coding_gene - - - "lncRNA:TS14, CR44336" - CR44336 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001761 l(1)M16 lethal (1) M16 http://flybase.org/reports/FBgn0001761 - gene - - - l(1)M16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259525 GG01477 - http://flybase.org/reports/FBgn0259525 gene - - - GG01477 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing vein L3,tarsal segment" FBgn0028186 l(3)S023941c lethal (3) S023941c http://flybase.org/reports/FBgn0028186 gene - - - "0239/41, l(3)S023941, l(3)S023941c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011919 tRNA:Met-CAT-1-5 transfer RNA:Methionine-CAT 1-5 http://flybase.org/reports/FBgn0011919 "FBgn0051310, FBgn0060141" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "Met-2, AE002699.trna7-MetCAT, tRNA:M:CAT:AE002699, CR31310, tRNA:met2:83F, tRNA[[e]][Met], chr3R.trna80-MetCAT, tRNA-Met[CAU], tRNA-Met-CAT-1-5, tRNA:Met-CAT-1-5, tRNA:M2:83F" - CR31310 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065261 l(2)SH2086 lethal (2) SH2086 http://flybase.org/reports/FBgn0065261 gene - - - "l(2)SH2086, l(2)SH2 2086" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265915 CR44704 - http://flybase.org/reports/FBgn0265915 non_protein_coding_gene - - - CR44704 - CR44704 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035611 CG13285 - http://flybase.org/reports/FBgn0035611 protein_coding_gene - - - "CG13285, FBgn0035611" - CG13285 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259417 C926 - http://flybase.org/reports/FBgn0259417 gene - - - C926 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0065286 l(2)SH2021 lethal (2) SH2021 http://flybase.org/reports/FBgn0065286 gene - - - "l(2)SH2021, l(2)SH2 2021" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045050 fs(1)250 female sterile (1) 250 http://flybase.org/reports/FBgn0045050 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)250 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "ovary,egg" FBgn0267676 CR46012 - http://flybase.org/reports/FBgn0267676 non_protein_coding_gene - - - CR46012 - CR46012 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260766 CG42564 - http://flybase.org/reports/FBgn0260766 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "CG42564, CG10284" "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG42564 11-Aug-17 DroID_v2017_08 "Drer\crispld1a, Drer\r3hdml, Drer\crispld2, Drer\pi15a, Drer\glipr1b, Drer\crispld1b, Drer\glipr2l, Drer\glipr2, Drer\pi15b, Drer\LOC100536500" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\scl-6, Cele\scl-1, Cele\scl-10, Cele\scl-23, Cele\scl-20, Cele\vap-2" "Xtro\MGC108118, Xtro\crisp1, Xtro\crispld2, Xtro\crisp2, Xtro\crisp3, Xtro\glipr2, Xtro\r3hdml" "Mmus\Crispld1, Mmus\Glipr1l2, Mmus\Clec18a, Mmus\Pi15, Mmus\Crisp2, Mmus\Crisp3, Mmus\Glipr1, Mmus\Crisp4, Mmus\Glipr1l1, Mmus\R3hdml, Mmus\Crisp1, Mmus\Crispld2, Mmus\Pi16, Mmus\Glipr2" "Hsap\GLIPR1, Hsap\PI15, Hsap\CRISP1, Hsap\CRISPLD1, Hsap\PI16, Hsap\CRISP2, Hsap\CLEC18C, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\R3HDML, Hsap\CLEC18A, Hsap\GLIPR1L1, Hsap\GLIPR2, Hsap\CLEC18B" viable FBgn0262904 CR43259 - http://flybase.org/reports/FBgn0262904 non_protein_coding_gene - - - CR43259 - CR43259 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040679 CG11373 - http://flybase.org/reports/FBgn0040679 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11373 - CG11373 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0020235 ATPsyngamma "ATP synthase, gamma subunit" http://flybase.org/reports/FBgn0020235 - protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000000243" proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P36542 ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000000243 phagocytosis ; GO:0006909 | inferred from mutant phenotype "lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P36542" "ATPsyn-gamma, CG7610, ATPsyn-gam, ATPG_DROME, ATPG, ATPsyngamma, ATP-syn-gamma" "IPR000131:ATP synthase, F1 complex, gamma subunit, IPR023632:ATP synthase, F1 complex, gamma subunit conserved site" CG7610 11-Aug-17 DroID_v2017_08 "Drer\taf3, Drer\atp5c1" Scer\ATP3 "Cele\Y69A2AR.18, Cele\taf-3" "Xtro\taf3, Xtro\atp5c1" "Mmus\Taf3, Mmus\Atp5c1" Hsap\ATP5C1 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC14094 K -0.302446263 -0.192940616 -0.880534713 -1.005323255 1.829306441 1.573020866 FBgn0065703 l(2)SH0619 lethal (2) SH0619 http://flybase.org/reports/FBgn0065703 gene - - - "l(2)SH0619, l(2)SH2 0619" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029606 CG14052 - http://flybase.org/reports/FBgn0029606 protein_coding_gene - - - CG14052 - CG14052 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC17907 I 2.181155943 -0.960851091 1.260429562 0.326207364 -0.084858147 0.354267025 FBgn0265756 CR44563 - http://flybase.org/reports/FBgn0265756 non_protein_coding_gene - - - "CR44563, lincRNA.588" - CR44563 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023198 JmY Ju-myoY http://flybase.org/reports/FBgn0023198 - gene - - - "Jm Y, Y, JmY" - - 11-Aug-17 DroID_v2017_08 - - - - - - aging defective FBgn0085466 CG34437 - http://flybase.org/reports/FBgn0085466 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "CG34437, CG16918, SPH201" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34437 11-Aug-17 DroID_v2017_08 - - "Cele\try-3, Cele\svh-1" - - "Hsap\PRTN3, Hsap\MASP1" FBgn0060455 l(3)S118608 lethal (3) S118608 http://flybase.org/reports/FBgn0060455 gene - - - "1186/08, l(3)S118608" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0040337 CG3021 - http://flybase.org/reports/FBgn0040337 protein_coding_gene sulfurtransferase activity ; GO:0016783 | inferred from electronic annotation with InterPro:IPR023382 tRNA wobble position uridine thiolation ; GO:0002143 | inferred from biological aspect of ancestor with PANTHER:PTN000232426 mitochondrial tRNA thio-modification ; GO:0070903 | inferred from biological aspect of ancestor with PANTHER:PTN000232429 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000232429 "EG:BACR7A4.8, anon-1Ed, E, CG3021" "IPR004506:tRNA-specific 2-thiouridylase, IPR023382:Adenine nucleotide alpha hydrolase-like domains, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG3021 11-Aug-17 DroID_v2017_08 Drer\trmu Scer\SLM3 Cele\mttu-1 Xtro\trmu Mmus\Trmu Hsap\TRMU viable FBgn0003580 Su(sph) Suppressor of sparse hairs http://flybase.org/reports/FBgn0003580 - gene - - - "Su-x4, Su(sph)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015978 l(2)PC4-D lethal (2) PC4-D http://flybase.org/reports/FBgn0015978 - gene - - - l(2)PC4-D - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026639 l(2)k10613 lethal (2) k10613 http://flybase.org/reports/FBgn0026639 - gene - - - l(2)k10613 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036652 CG13032 - http://flybase.org/reports/FBgn0036652 protein_coding_gene - - - CG13032 - CG13032 11-Aug-17 DroID_v2017_08 Drer\ccdc13 - - Xtro\ccdc13 Mmus\Ccdc13 Hsap\CCDC13 viable FBgn0040648 CG11666 - http://flybase.org/reports/FBgn0040648 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11666 - CG11666 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0067348 l(3)95Ed lethal (3) 95Ed http://flybase.org/reports/FBgn0067348 gene - - - l(3)95Ed - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,somatic clone,wing margin,macrochaeta" FBgn0020369 Rpt6 Regulatory particle triple-A ATPase 6 http://flybase.org/reports/FBgn0020369 FBgn0023422 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ATPase activity ; GO:0016887 | inferred from sequence model proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000003016 proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9552 inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from direct assay nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" "p42C, dRpt6, Dm_Rpt6a, DUG, pros45, sug1, sug-1, Ug, Dug, CG1489, Rpt6, 1489, PRS8_DROME, S8, Pros45" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1489 11-Aug-17 DroID_v2017_08 "Drer\psmc5, Drer\psmc6, Drer\wdr12, Drer\psmc2" Scer\RPT6 "Cele\rpt-4, Cele\C10G11.8, Cele\rpt-6, Cele\F56F11.4" "Xtro\psmc6, Xtro\psmc2, Xtro\wdr12, Xtro\psmc5" "Mmus\Wdr12, Mmus\Psmc2, Mmus\Psmc6, Mmus\Psmc5" "Hsap\PSMC6, Hsap\WDR12, Hsap\PSMC2, Hsap\PSMC5" " embryonic stage | stage 13 , embryonic stage | stage 16 , adult stage | male , embryonic stage--pupal stage , larval stage | first instar , embryonic stage | early , adult stage | female , embryonic stage " " posterior midgut proper primordium

, embryonic central nervous system

, anterior midgut proper primordium

, larval nervous system

,

ubiquitous , pole cell | stage 5-8

" embryonic stage -- adult stage "viable,fertile,lethal,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0069419 JJF106 JJF106 http://flybase.org/reports/FBgn0069419 gene - - - JJF106 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0031333 CG5561 - http://flybase.org/reports/FBgn0031333 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 CG5561 "IPR023198:Phosphoglycolate phosphatase, domain 2, IPR006439:HAD hydrolase, subfamily IA, IPR023214:HAD-like domain" CG5561 11-Aug-17 DroID_v2017_08 Drer\pudp "Scer\YKL033W-A, Scer\GPP1, Scer\DOG2, Scer\GPP2, Scer\DOG1" Cele\R151.10 Xtro\pudp Mmus\Hdhd1a Hsap\PUDP "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0004528 l(4)102ABe lethal (4) 102ABe http://flybase.org/reports/FBgn0004528 - gene - - - "l(4)18, l(4)35, l(4)102ABe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0267569 CR45909 - http://flybase.org/reports/FBgn0267569 non_protein_coding_gene - - - CR45909 - CR45909 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000519 dwf dwarfoid http://flybase.org/reports/FBgn0000519 - gene - - - dwf - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced,male fertile,female fertile,female sterile,recessive,poor" "adult abdomen,adult thorax" FBgn0029513 Abd-B-PTS Abdominal B promoter targeting sequence http://flybase.org/reports/FBgn0029513 regulatory_region - - - "PTS-7, PTS, Abd-B-PTS" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003259 Rm2 Ring magnifier on 2 http://flybase.org/reports/FBgn0003259 - gene - - - Rm2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032372 CG4988 - http://flybase.org/reports/FBgn0032372 protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718 aldose 1-epimerase activity ; GO:0004034 | inferred from biological aspect of ancestor with PANTHER:PTN000009552" galactose catabolic process via UDP-galactose ; GO:0033499 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 glucose metabolic process ; GO:0006006 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 - CG4988 "IPR008183:Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013:Galactose mutarotase-like domain, IPR014718:Glycoside hydrolase-type carbohydrate-binding, IPR015443:Aldose 1-epimerase" CG4988 11-Aug-17 DroID_v2017_08 "Drer\galm, Drer\lfng, Drer\rfng, Drer\mfng" "Scer\GAL10, Scer\YNR071C, Scer\YHR210C" "Cele\Y19D10A.16, Cele\C01B4.6" "Xtro\galm, Xtro\rfng, Xtro\lfng" "Mmus\Galm, Mmus\Lfng, Mmus\Mfng, Mmus\Rfng" "Hsap\LFNG, Hsap\GALM, Hsap\MFNG, Hsap\RFNG" FBgn0033880 CG6553 - http://flybase.org/reports/FBgn0033880 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG6553 "IPR000436:Sushi/SCR/CCP domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site" CG6553 11-Aug-17 DroID_v2017_08 "Drer\ldlra, Drer\scospondin, Drer\lrp3, Drer\lrp8, Drer\lrp12, Drer\lrp1bb, Drer\lrp1ba, Drer\lrp10, Drer\LOC100536757, Drer\ldlrad3, Drer\si:dkey-258f14.3, Drer\sorl1, Drer\lrp1ab" "Scer\APM3, Scer\APM2, Scer\APM1" "Cele\rme-2, Cele\F32E10.8, Cele\M03E7.4, Cele\F09B12.5" "Xtro\lrp12, Xtro\lrp2, Xtro\sorl1, Xtro\lrp4, Xtro\lrp10, Xtro\lrp1" "Mmus\Lrp4, Mmus\Ldlrad1, Mmus\Cd320, Mmus\Lrp10, Mmus\Lrp1b, Mmus\LOC102637808, Mmus\Lrp3, Mmus\Lrp1, Mmus\Lrp2, Mmus\Sspo, Mmus\Lrp12, Mmus\Sorl1" "Hsap\LRP3, Hsap\LRP1, Hsap\LRP4, Hsap\LRP5L, Hsap\SORL1, Hsap\CD320, Hsap\LDLRAD1, Hsap\LRP1B, Hsap\LRP10, Hsap\LRP12, Hsap\LRP2" viable FBgn0028263 l(2)56Da lethal (2) 56Da http://flybase.org/reports/FBgn0028263 gene - - - l(2)56Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011445 l(3)neo1 lethal (3) neo1 http://flybase.org/reports/FBgn0011445 - gene - - - l(3)neo1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036372 Abp1 Actin binding protein 1 http://flybase.org/reports/FBgn0036372 protein_coding_gene "phosphatidylinositol-3,4,5-trisphosphate binding ; GO:0005547 | inferred from direct assay actin filament binding ; GO:0051015 | inferred from direct assay actin binding ; GO:0003779 | inferred by curator from GO:0005856 actin binding ; GO:0003779 | inferred from sequence or structural similarity phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from direct assay phosphatidylserine binding ; GO:0001786 | inferred from direct assay" chaeta development ; GO:0022416 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype cell migration ; GO:0016477 | NOT inferred from direct assay terminal button organization ; GO:0072553 | inferred from mutant phenotype actin filament ; GO:0005884 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay type Ib terminal bouton ; GO:0061176 | inferred from direct assay type Is terminal bouton ; GO:0061177 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay cortical actin cytoskeleton ; GO:0030864 | colocalizes_with inferred from direct assay cytoskeleton ; GO:0005856 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "CG10083, Abp1, abp1" "IPR001452:SH3 domain, IPR002108:Actin-depolymerising factor homology domain, IPR029006:ADF-H/Gelsolin-like domain" CG10083 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-40c11.2, Drer\dbnlb, Drer\lasp1, Drer\dbnla, Drer\dbn1, Drer\lima1a, Drer\cotl1" Scer\ABP1 "Cele\F42H10.3, Cele\dbn-1" "Xtro\dbnl, Xtro\dbn1" "Mmus\Lasp1, Mmus\Dbnl, Mmus\Dbn1" "Hsap\DBN1, Hsap\LASP1, Hsap\DBNL" "viable,fertile" "microchaeta,dorsocentral bristle" FBgn0028376 gut-X gut-X http://flybase.org/reports/FBgn0028376 gene - - - gut-X - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083918 CTTbp CTT DNA binding protein http://flybase.org/reports/FBgn0083918 gene - - - CTTbp - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260754 CG42552 - http://flybase.org/reports/FBgn0260754 protein_coding_gene - - - "CG42552, mdcds_30721" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085755 CR40611 - http://flybase.org/reports/FBgn0085755 rRNA_gene - - - CR40611 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261532 cdm cadmus http://flybase.org/reports/FBgn0261532 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype modulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 "3R23, CG7212, cdm, imp13, sd-5, CG 7212, Imp13" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR013598:Exportin-1/Importin-beta-like" CG7212 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-182a11.2, Drer\ipo13" "Scer\MTR10, Scer\KAP122" Cele\T16G12.6 Xtro\ipo13 Mmus\Ipo13 Hsap\IPO13 FBgn0022809 E(faf)bE184 Enhancer of faf bE184 http://flybase.org/reports/FBgn0022809 - gene - - - E(faf)bE184 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,wing" FBgn0035949 CG13314 - http://flybase.org/reports/FBgn0035949 protein_coding_gene - - - CG13314 - CG13314 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041739 l(2)EL3 lethal (2) EL3 http://flybase.org/reports/FBgn0041739 gene - - - l(2)EL3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000496 drw droopy wings http://flybase.org/reports/FBgn0000496 - gene - - - "dr, drw" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,reduced,male sterile,body color defective" "wing,adult cuticle & abdomen,microchaeta,trichome" FBgn0003930 snRNA:U4:39B small nuclear RNA U4 at 39B http://flybase.org/reports/FBgn0003930 "FBgn0003929, FBgn0021997, FBgn0051625" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U4 snRNP ; GO:0005687 | inferred from sequence or structural similarity "U4:39B, U4, U4-39B, U4-2, K3, l(2)k09410, dU4, snRNA:U4, U4snRNA39B, CR31625, U4snRNA, snRNA:U4:39B, U4 snRNA, U4:39B snRNA, chr2L:21202607..21202764, U4-snRNA" - CR31625 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065844 l(2)SH0320 lethal (2) SH0320 http://flybase.org/reports/FBgn0065844 gene - - - "l(2)SH0320, l(2)SH2 0320" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060705 l(3)S070806c lethal (3) S070806c http://flybase.org/reports/FBgn0060705 gene - - - "0708/06, l(3)S070806c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039474 CG6283 - http://flybase.org/reports/FBgn0039474 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG6283, DmelL3" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6283 11-Aug-17 DroID_v2017_08 "Drer\LOC101884800, Drer\LOC100331214, Drer\lipib, Drer\pla1a, Drer\lpl, Drer\lipg, Drer\lipca, Drer\lipia" - - "Xtro\lipg, Xtro\lpl" "Mmus\Pla1a, Mmus\Pnliprp2, Mmus\Lipg, Mmus\Lipi, Mmus\Pnlip, Mmus\Pnliprp1, Mmus\Lipc, Mmus\Liph, Mmus\Lpl" "Hsap\LIPH, Hsap\LIPG, Hsap\LIPC, Hsap\PNLIP, Hsap\LPL, Hsap\LIPI, Hsap\PLA1A, Hsap\PNLIPRP2, Hsap\PNLIPRP3, Hsap\PNLIPRP1" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0264672 Eogt EGF-domain O-GlcNAc transferase http://flybase.org/reports/FBgn0264672 protein_coding_gene protein O-GlcNAc transferase activity ; GO:0097363 | inferred from mutant phenotype protein N-acetylglucosaminyltransferase activity ; GO:0016262 | inferred from direct assay protein O-GlcNAc transferase activity ; GO:0097363 | inferred from direct assay metabolic process ; GO:0008152 | inferred from direct assay protein O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype protein O-GlcNAcylation via threonine ; GO:0097370 | inferred from mutant phenotype protein O-linked glycosylation ; GO:0006493 | inferred from direct assay endoplasmic reticulum lumen ; GO:0005788 | inferred from direct assay "Eogt, eogt, CG9867" IPR007657:Glycosyltransferase 61 CG9867 11-Aug-17 DroID_v2017_08 "Drer\eogt, Drer\pomgnt2" - Cele\H12D21.10 "Xtro\eogt, Xtro\pomgnt2" "Mmus\Eogt, Mmus\Pomgnt2" "Hsap\EOGT, Hsap\POMGNT2" FBgn0054056 CG34056 - http://flybase.org/reports/FBgn0054056 protein_coding_gene "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 beta-1,3-galactosyltransferase activity ; GO:0048531 | inferred from direct assay" "protein glycosylation ; GO:0006486 | inferred from direct assay O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 cellular_component ; GO:0005575 | no biological data available "CG13904, CG34056, CG13904-1, dC1GalT6" IPR003378:Fringe-like CG34056 11-Aug-17 DroID_v2017_08 "Drer\c1galt1a, Drer\c1galt1c1, Drer\LOC564281, Drer\si:dkey-202e17.1, Drer\c1galt1b" - "Cele\T09E11.6, Cele\E03H4.3, Cele\F56H6.1, Cele\T09E11.12, Cele\Y38C1AB.1, Cele\W09D10.5, Cele\C02H6.1, Cele\C38H2.2, Cele\F37A4.3, Cele\Y38C1AB.5, Cele\bus-4, Cele\C17A2.3, Cele\C16D9.6" "Xtro\c1galt1, Xtro\LOC100496837" "Mmus\C1galt1c1, Mmus\C1galt1" "Hsap\C1GALT1C1, Hsap\C1GALT1" viable DRSC08374 K -1.091978318 -0.12304542 -0.725386361 -0.103073032 1.689179205 -0.025373903 FBgn0010580 l(2)04535b lethal (2) 04535b http://flybase.org/reports/FBgn0010580 - gene - - - "l(2)04535, l(2)04535b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043998 Su(rst)C478 Su(rst)C478 http://flybase.org/reports/FBgn0043998 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C478, Su(rst)C478" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005297 mei-B meiotic B http://flybase.org/reports/FBgn0005297 - gene - - - mei-B - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,female,recessive,fertile,poor" FBgn0020606 anon-34Da anon-34Da http://flybase.org/reports/FBgn0020606 - gene - - - "cDNA 7, anon-34Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259826 ifm(2)RS10 indirect flight muscle (2) RS10 http://flybase.org/reports/FBgn0259826 gene - adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS10 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable indirect flight muscle FBgn0002208 l(3)67BDf lethal (3) 67BDf http://flybase.org/reports/FBgn0002208 - gene - - - l(3)67BDf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0034598 CG4266 - http://flybase.org/reports/FBgn0034598 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "CG4266, cg4266" "IPR000504:RNA recognition motif domain, IPR006569:CID domain, IPR006903:RNA polymerase II-binding domain, IPR008942:ENTH/VHS" CG4266 11-Aug-17 DroID_v2017_08 "Drer\scaf8, Drer\scaf4b, Drer\scaf4a" Scer\NRD1 Cele\nrd-1 "Xtro\scaf4, Xtro\scaf8" "Mmus\Scaf8, Mmus\Scaf4" "Hsap\SCAF8, Hsap\SCAF4" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0260282 GSd478 - http://flybase.org/reports/FBgn0260282 gene - - - GSd478 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0023069 l(1)20Ah lethal (1) 20Ah http://flybase.org/reports/FBgn0023069 - gene - - - "A2/25, l(1)20Ah" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265803 CR44592 - http://flybase.org/reports/FBgn0265803 non_protein_coding_gene - - - "CR44592, Mgn00375" - CR44592 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044375 anon-AE003825.1 anon-AE003825.1 http://flybase.org/reports/FBgn0044375 gene - - - anon-AE003825.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031050 Arp10 Actin-related protein 10 http://flybase.org/reports/FBgn0031050 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from direct assay cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity dynactin complex ; GO:0005869 | inferred from sequence or structural similarity with MGI:MGI:1891654 actin filament ; GO:0005884 | inferred from sequence or structural similarity "CG12235, ARP11, Arp11, Arp10" "IPR004000:Actin family, IPR027127:Actin-related protein 10" CG12235 11-Aug-17 DroID_v2017_08 "Drer\actb1, Drer\si:ch211-241j12.3, Drer\acta2, Drer\actr10, Drer\zgc:86725, Drer\actc1b, Drer\actr1, Drer\ankrd52b, Drer\acta1b, Drer\actc1a, Drer\acta1a, Drer\zgc:86709, Drer\actb2, Drer\si:ch73-187m15.4" "Scer\ACT1, Scer\ARP9, Scer\ARP1, Scer\ARP10" Cele\arp-11 "Xtro\acta2, Xtro\act3, Xtro\actr1a, Xtro\actb, Xtro\actr10, Xtro\actg1, Xtro\actc1, Xtro\ankrd52, Xtro\acta1" "Mmus\Actr10, Mmus\Acta1, Mmus\Actbl2, Mmus\Actl10, Mmus\Acta2, Mmus\Actl9, Mmus\Actrt2, Mmus\Actg2, Mmus\Actl7b, Mmus\Actl7a, Mmus\Actl11, Mmus\Actr1a, Mmus\Actr1b, Mmus\Actrt1, Mmus\Actb, Mmus\Actg1, Mmus\Actc1, Mmus\Actrt3" "Hsap\ACTBL2, Hsap\ACTG1, Hsap\ACTR1A, Hsap\ACTRT1, Hsap\ACTL8, Hsap\POTEJ, Hsap\ACTL7B, Hsap\ACTC1, Hsap\POTEE, Hsap\ACTR10, Hsap\ACTG2, Hsap\ACTL9, Hsap\ACTL7A, Hsap\ACTRT3, Hsap\ACTRT2, Hsap\ACTA1, Hsap\POTEF, Hsap\ACTA2, Hsap\ACTL10, Hsap\ACTB, Hsap\ACTR1B, Hsap\POTEI" "lethal,recessive,partially lethal - majority die,visible" mesothoracic tergum FBgn0042160 CG18837 - http://flybase.org/reports/FBgn0042160 protein_coding_gene - - - CG18837 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083992 Mkp MAP kinase-specific phosphatase http://flybase.org/reports/FBgn0083992 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | inferred from sequence or structural similarity with HGNC:3072 protein dephosphorylation ; GO:0006470 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "CG34099, CG7042, DMKP, Mkp, MKP, mkp" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like" CG34099 11-Aug-17 DroID_v2017_08 "Drer\zgc:153044, Drer\dusp10, Drer\ssh1a, Drer\dusp7, Drer\dusp19b, Drer\dusp27, Drer\si:dkey-175m17.7, Drer\dusp8a, Drer\dusp3b, Drer\dusp3a, Drer\si:ch211-121a2.2, Drer\dusp5, Drer\si:ch1073-184j22.2, Drer\styxl1, Drer\dusp22a, Drer\si:ch211-223p8.8, Drer\si:ch211-195b15.8, Drer\dusp19a, Drer\dusp16, Drer\ssh2a, Drer\dusp8b, Drer\dupd1, Drer\dusp22b, Drer\dusp12, Drer\dusp14, Drer\dusp13a, Drer\dusp6, Drer\styx, Drer\si:ch211-203d1.3, Drer\dusp2, Drer\ssh1b, Drer\ssh2b, Drer\dusp4, Drer\zgc:153981, Drer\dusp1" "Scer\YVH1, Scer\PPS1, Scer\SDP1, Scer\MSG5" "Cele\lip-1, Cele\Y54F10BM.13, Cele\F26A3.4, Cele\C24F3.2, Cele\C04F12.8, Cele\F13D11.3, Cele\C16A3.2" "Xtro\dusp4, Xtro\dusp6, Xtro\dusp26, Xtro\styxl1, Xtro\dusp18, Xtro\ssh1, Xtro\dusp19, Xtro\dusp12, Xtro\dusp10, Xtro\dusp1, Xtro\ssh2, Xtro\epm2a, Xtro\dusp5, Xtro\dusp22a, Xtro\styx, Xtro\dusp22, Xtro\dupd1, Xtro\dusp9" "Mmus\Dusp9, Mmus\Dusp12, Mmus\Dusp5, Mmus\Dusp19, Mmus\Dusp2, Mmus\Dusp10, Mmus\Styxl1, Mmus\Dusp22, Mmus\Dusp1, Mmus\Dusp6, Mmus\Dusp21, Mmus\Dusp13, Mmus\Ssh3, Mmus\Dupd1, Mmus\Dusp14, Mmus\Styx, Mmus\Dusp26, Mmus\Dusp7, Mmus\Dusp18, Mmus\Epm2a, Mmus\Ssh1, Mmus\Dusp16, Mmus\Dusp15, Mmus\Dusp8, Mmus\Dusp4, Mmus\Ssh2, Mmus\Dusp27, Mmus\Dusp3" "Hsap\EPM2A, Hsap\STYXL1, Hsap\STYX, Hsap\SSH3, Hsap\SSH1, Hsap\DUSP19, Hsap\SSH2, Hsap\DUSP13, Hsap\DUSP9, Hsap\DUSP6, Hsap\DUSP4, Hsap\DUSP27, Hsap\DUSP22, Hsap\DUSP5, Hsap\DUSP8, Hsap\DUPD1, Hsap\DUSP1, Hsap\DUSP18, Hsap\DUSP21, Hsap\DUSP12, Hsap\DUSP10, Hsap\DUSP16, Hsap\DUSP7, Hsap\DUSP2, Hsap\DUSP15, Hsap\DUSP3, Hsap\DUSP26" "viable,fertile" FBgn0037744 CG8417 - http://flybase.org/reports/FBgn0037744 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001250 mannose-6-phosphate isomerase activity ; GO:0004476 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001250 GDP-mannose biosynthetic process ; GO:0009298 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 protein glycosylation ; GO:0006486 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 cell wall mannoprotein biosynthetic process ; GO:0000032 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 CG8417 "IPR001250:Mannose-6-phosphate isomerase, type I, IPR011051:RmlC-like cupin domain, IPR018050:Phosphomannose isomerase, type I, conserved site, IPR014710:RmlC-like jelly roll fold, IPR016305:Mannose-6-phosphate isomerase" CG8417 11-Aug-17 DroID_v2017_08 Drer\mpi Scer\PMI40 "Cele\C05C8.7, Cele\ZK632.4" Xtro\mpi Mmus\Mpi Hsap\MPI "viable,fertile" DRSC16417 K 0.032044333 -0.721649006 -0.376776952 0.478878772 0.204585862 -1.539098019 FBgn0085472 CG34443 - http://flybase.org/reports/FBgn0085472 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34443, CG30070" IPR006631:Protein of unknown function DM4/12 CG34443 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041605 cpx complexin http://flybase.org/reports/FBgn0041605 protein_coding_gene syntaxin binding ; GO:0019905 | inferred from electronic annotation with InterPro:IPR008849 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with UniProtKB:P63040 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity regulation of neurotransmitter secretion ; GO:0046928 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity with UniProtKB:P63040 modulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype neuromuscular junction ; GO:0031594 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with UniProtKB:Q8R1B5 presynaptic active zone ; GO:0048786 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG32490, BcDNA:HL04936, BcDNA:RH31085, BcDNA:RH26459, BcDNA:GH27718, cpx, Cpx, dmCplx, DmCpx, CPX" IPR008849:Synaphin CG32490 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-81a5.8, Drer\cplx3a, Drer\cplx2l, Drer\cplx4c, Drer\cplx2, Drer\cplx4b, Drer\LOC563082, Drer\cplx3b, Drer\cplx4a" - "Cele\cpx-2, Cele\cpx-1" "Xtro\cplx2, Xtro\cplx1" "Mmus\Cplx2, Mmus\Cplx3, Mmus\Cplx1, Mmus\Cplx4" "Hsap\CPLX1, Hsap\CPLX3, Hsap\CPLX2, Hsap\CPLX4" "partially lethal,uncoordinated,neurophysiology defective,viable,fertile,heat sensitive,visible,partially lethal - majority die,some die during pupal stage,locomotor behavior defective,sterile,wild-type" "embryonic/larval neuromuscular junction | third instar larval stage,adult neuromuscular junction,embryonic/larval neuromuscular junction,mesothoracic tergum" FBgn0266687 CR45177 - http://flybase.org/reports/FBgn0266687 non_protein_coding_gene - - - CR45177 - CR45177 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263934 esn espinas http://flybase.org/reports/FBgn0263934 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781, InterPro:IPR010442" dendrite self-avoidance ; GO:0070593 | inferred from mutant phenotype - "CG43722, esn, CG12833, CG12835, Dm_2R:11728" "IPR010442:PET domain, IPR001781:Zinc finger, LIM-type, IPR033725:LIM1 prickle, IPR033727:LIM3 prickle, IPR033723:PET prickle, IPR033726:LIM2 prickle" CG43722 11-Aug-17 DroID_v2017_08 "Drer\znf185, Drer\fhl1b, Drer\lmo7a, Drer\fhl2b, Drer\fhl3b, Drer\tes, Drer\limd2, Drer\prickle3, Drer\prickle2b, Drer\limch1a, Drer\prickle1a, Drer\fhl3a, Drer\fhl2a, Drer\limch1b, Drer\lmo7b, Drer\prickle2a, Drer\fhl1a, Drer\prickle1b" "Scer\RGA2, Scer\RGA1, Scer\LRG1" "Cele\tes-1, Cele\lim-9, Cele\prkl-1" "Xtro\fhl2, Xtro\lmo7, Xtro\prickle1, Xtro\lmcd1, Xtro\prickle2, Xtro\fhl3, Xtro\tes, Xtro\scel, Xtro\fhl1, Xtro\limch1, Xtro\fhl5" "Mmus\Lmcd1, Mmus\Fhl2, Mmus\Tes, Mmus\Prickle3, Mmus\Prickle1, Mmus\Limd2, Mmus\Zfp185, Mmus\Lmo7, Mmus\Fhl1, Mmus\Fhl3, Mmus\Prickle2, Mmus\Prickle4, Mmus\Fhl5, Mmus\Fhl4, Mmus\Gm4907" "Hsap\LMCD1, Hsap\PRICKLE4, Hsap\FHL5, Hsap\PRICKLE1, Hsap\FHL3, Hsap\FHL1, Hsap\LIMD2, Hsap\PRICKLE2, Hsap\TES, Hsap\ZNF185, Hsap\LMO7, Hsap\FHL2, Hsap\PRICKLE3" FBgn0002802 ms(1)19Fa male sterile (1) 19Fa http://flybase.org/reports/FBgn0002802 - gene - - - "ms(1)D, ms(1)19Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0025503 l(3)73Ak lethal (3) 73Ak http://flybase.org/reports/FBgn0025503 - gene - - - l(3)73Ak - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051697 CG31697 - http://flybase.org/reports/FBgn0051697 protein_coding_gene - - - "CG10355, CG31697" - CG31697 11-Aug-17 DroID_v2017_08 "Drer\cept1b, Drer\cept1a, Drer\chpt1, Drer\si:ch211-197l9.4" "Scer\EPT1, Scer\CPT1" - "Xtro\cept1, Xtro\ept1, Xtro\chpt1" "Mmus\Chpt1, Mmus\Selenoi, Mmus\Cept1" "Hsap\SELENOI, Hsap\CEPT1, Hsap\CHPT1" viable FBgn0060665 l(3)S080707a lethal (3) S080707a http://flybase.org/reports/FBgn0060665 gene - - - "0807/07, l(3)S080707a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0024542 Neos Neosin http://flybase.org/reports/FBgn0024542 FBgn0027902 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG8614, BcDNA:HL05936, l(3)L2249, BcDNA.HL05936, Neos" "IPR000504:RNA recognition motif domain, IPR004154:Anticodon-binding" CG8614 11-Aug-17 DroID_v2017_08 "Drer\raly, Drer\ncoa5, Drer\si:ch211-216l23.2, Drer\nup98" Scer\NUP145 "Cele\col-17, Cele\ztf-4" "Xtro\nup98, Xtro\LOC100145527, Xtro\ncoa5" "Mmus\Ncoa5, Mmus\Nup98" "Hsap\NCOA5, Hsap\NUP98, Hsap\RALY" "lethal,recessive,viable" DRSC11235 I 2.321832856 1.378441246 0.627364268 0.071544028 -0.693101126 -1.086718639 FBgn0065209 l(2)SH2263 lethal (2) SH2263 http://flybase.org/reports/FBgn0065209 gene - - - "l(2)SH2263, l(2)SH2 2263" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016866 l(2)39ADd lethal (2) 39ADd http://flybase.org/reports/FBgn0016866 - gene - - - "H221, l(2)39ADd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035057 CG3880 - http://flybase.org/reports/FBgn0035057 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3880 "IPR011992:EF-hand domain pair, IPR026828:Suppressor APC domain-containing protein 1/2" CG3880 11-Aug-17 DroID_v2017_08 Drer\sapcd2 - Cele\T01B6.1 - "Mmus\Sapcd1, Mmus\Sapcd2" "Hsap\SAPCD2, Hsap\SAPCD1" viable FBgn0082994 snoRNA:Psi28S-1837c snoRNA:Psi28S-1837c http://flybase.org/reports/FBgn0082994 snoRNA_gene - - - "snoRNA:Psi28S-1837c, Psi28S-1837c, psi28S-1837c, CR34638" - CR34638 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023545 PIG-K Phosphatidylinositol glycan anchor biosynthesis class K http://flybase.org/reports/FBgn0023545 - protein_coding_gene peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR001096 GPI-anchor transamidase activity ; GO:0003923 | inferred from sequence or structural similarity with UniProtKB:Q92643 GPI-anchor transamidase activity ; GO:0003923 | inferred from biological aspect of ancestor with PANTHER:PTN000243120 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001096 attachment of GPI anchor to protein ; GO:0016255 | inferred from biological aspect of ancestor with PANTHER:PTN000243120 protein localization to cell surface ; GO:0034394 | inferred from biological aspect of ancestor with PANTHER:PTN000243120 GPI-anchor transamidase complex ; GO:0042765 | inferred from sequence or structural similarity with UniProtKB:Q92643 GPI-anchor transamidase complex ; GO:0042765 | inferred from biological aspect of ancestor with PANTHER:PTN000243120 "EG:133E12.3, cg4406, PIG-K, CG4406" "IPR001096:Peptidase C13, legumain, IPR028361:GPI-anchor transamidase" CG4406 11-Aug-17 DroID_v2017_08 Drer\pigk Scer\GPI8 Cele\hpo-4 Xtro\pigk Mmus\Pigk Hsap\PIGK FBgn0002602 M(2)44C Minute (2) 44C http://flybase.org/reports/FBgn0002602 - gene - - - "M(2)38b, M(2)44C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011033 l(3)s2681 lethal (3) s2681 http://flybase.org/reports/FBgn0011033 - gene - - - l(3)s2681 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051155 Rpb7 Rpb7 http://flybase.org/reports/FBgn0051155 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003029 protein binding ; GO:0005515 | inferred from physical interaction with Rpb4 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9194 inferred from sequence or structural similarity with SGD:S000002812 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9194 inferred from sequence or structural similarity with SGD:S000002812 "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from physical interaction with Rpb4 DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9194 inferred from sequence or structural similarity with SGD:S000002812" "dRpb7, RPB7, CG6572, CG31155, Rpb7" "IPR003029:S1 domain, IPR005576:RNA polymerase Rpb7, N-terminal, IPR012340:Nucleic acid-binding, OB-fold" CG31155 11-Aug-17 DroID_v2017_08 Drer\polr2gl Scer\RPB7 Cele\rpb-7 Xtro\polr2g Mmus\Polr2g Hsap\POLR2G "viable,fertile,lethal" DRSC16068 IEK 2.650413799 3.198140773 -1.997283187 -2.38056349 2.423196075 1.066874048 FBgn0040365 CG14628 - http://flybase.org/reports/FBgn0040365 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "EG:BACR42I17.12, cg14628, CG14628" IPR000504:RNA recognition motif domain CG14628 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-216l23.2, Drer\ncoa5" - - "Xtro\LOC100145527, Xtro\ncoa5" Mmus\Ncoa5 - viable FBgn0267817 CR46142 - http://flybase.org/reports/FBgn0267817 non_protein_coding_gene - - - CR46142 - CR46142 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003943 Ubi-p63E Ubiquitin-63E http://flybase.org/reports/FBgn0003943 - protein_coding_gene protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000003962 male meiosis I ; GO:0007141 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype ubiquitin homeostasis ; GO:0010992 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000003962 autophagy ; GO:0006914 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "Ub, ubi63E, DmUb, CG11624, Ubi63E, Ubi-p, Ubp, Ubip, Ubi-p63E, Ubiq, Ubi63p, ubi, ubi-p63E, Ubi-P63e, DmUbi-p63E, Ubip63E, magn, UB, Ub-p63E" "IPR000626:Ubiquitin domain, IPR019954:Ubiquitin conserved site, IPR019956:Ubiquitin, IPR029071:Ubiquitin-related domain" CG11624 11-Aug-17 DroID_v2017_08 "Drer\zgc:56596, Drer\zfand4, Drer\faub, Drer\ubc, Drer\uba52, Drer\si:ch211-202a12.4, Drer\ubb, Drer\kxd1, Drer\isg15, Drer\faua, Drer\nedd8, Drer\nedd8l" Scer\UBI4 "Cele\F52C6.3, Cele\ubq-1, Cele\F52C6.2, Cele\ned-8, Cele\ubq-2, Cele\kxd-1" "Xtro\fau, Xtro\nedd8, Xtro\rps27a, Xtro\uba52, Xtro\kxd1, Xtro\ubl4a, Xtro\zfand4, Xtro\LOC100485835, Xtro\ubc" "Mmus\Oasl1, Mmus\Fau, Mmus\Oas1a, Mmus\Ubc, Mmus\Oas3, Mmus\Oas2, Mmus\Ubl4a, Mmus\Rps27a, Mmus\Zfand4, Mmus\Oasl2, Mmus\Nedd8, Mmus\Oas1g, Mmus\Ubl4b, Mmus\Ubd, Mmus\Isg15, Mmus\Ubb" "Hsap\OAS2, Hsap\UBD, Hsap\OASL, Hsap\UBC, Hsap\ZFAND4, Hsap\OAS1, Hsap\UBA52, Hsap\UBL4B, Hsap\OAS3, Hsap\RPS27A, Hsap\UBL4A, Hsap\UBB, Hsap\ISG15, Hsap\NEDD8" " embryonic stage -- adult stage , embryonic stage && larval stage && pupal stage "

"increased cell death,viable,fertile,male sterile,meiotic cell cycle defective,male limited,female fertile,cell autonomous,somatic clone" "testis,spermatocyte,cell autonomous,somatic clone" DRSC08703 IEK -2.616524024 -5.089831517 -0.197005128 -7.250994117 -7.566134038 -5.573509512 FBgn0036227 CG17826 - http://flybase.org/reports/FBgn0036227 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG17826 IPR002557:Chitin binding domain CG17826 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\W03F11.1, Cele\R02F2.4, Cele\cbd-1, Cele\cpg-2" - - Hsap\MATN2 viable FBgn0243516 Vrp1 Verprolin 1 http://flybase.org/reports/FBgn0243516 protein_coding_gene actin filament binding ; GO:0051015 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype visceral muscle development ; GO:0007522 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype positive regulation of actin filament polymerization ; GO:0030838 | inferred from direct assay myoblast fusion ; GO:0007520 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay filopodium tip ; GO:0032433 | inferred from direct assay "wip, CG13503, Vrp1, sltr, D-WIP, solas, Dm_Vrp1, dWIP, vrp1, WIP, vrp, Sltr, DWIP" IPR003124:WH2 domain CG13503 11-Aug-17 DroID_v2017_08 "Drer\wipf1a, Drer\wipf2b, Drer\wipf1b, Drer\wipf2a, Drer\sb:cb649" Scer\VRP1 Cele\wip-1 "Xtro\wipf1, Xtro\wipf2" "Mmus\Wipf1, Mmus\Wipf2, Mmus\Wipf3" "Hsap\WIPF1, Hsap\WIPF2, Hsap\WIPF3" DRSC04148 I 0.547844328 -1.546639217 -1.340155535 -0.557923259 0.103537673 -0.36560665 FBgn0004806 fs(2)ltoRV64 female sterile (2) ltoRV64 http://flybase.org/reports/FBgn0004806 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoRV64 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0016024 l(3)89Bm lethal (3) 89Bm http://flybase.org/reports/FBgn0016024 - gene - - - l(3)89Bm - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261508 CG42656 - http://flybase.org/reports/FBgn0261508 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42656, DMG8-chr3R.6.013" - CG42656 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036008 CG3408 - http://flybase.org/reports/FBgn0036008 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CT11439, CG3408" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG3408 11-Aug-17 DroID_v2017_08 "Drer\lrrc59, Drer\lrrc18a, Drer\lrrc18b" - Cele\F56A8.3 "Xtro\lrrc59, Xtro\lrrc18" Mmus\Lrrc59 "Hsap\LRRC18, Hsap\LRRC59" viable FBgn0265811 CR44600 - http://flybase.org/reports/FBgn0265811 non_protein_coding_gene - - - CR44600 - CR44600 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019688 l(3)96Aa lethal (3) 96Aa http://flybase.org/reports/FBgn0019688 - gene - - - "291.5, l(3)96Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,heat sensitive,some die during larval stage" FBgn0028017 l(3)S105307 lethal (3) S105307 http://flybase.org/reports/FBgn0028017 gene - - - "1053/07, l(3)S105307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051494 tRNA:Gly-TCC-1-1 transfer RNA:Glycine-TCC 1-1 http://flybase.org/reports/FBgn0051494 tRNA_gene GGA codon-amino acid adaptor activity ; GO:0033463 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033463 cytosol ; GO:0005829 | inferred by curator from GO:0033463 "AE002699.trna11-GlyTCC, tRNA[Gly][[GGA]], tRNA:gly:84C, tRNA:G:84C, tRNA:G:TCC:AE002699-b, CR31494, chr3R.trna4-GlyTCC, tRNA-Gly-TCC-1-1, tRNA:Gly-TCC-1-1, tRNA:CR31494, GGA" - CR31494 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039078 CG4374 - http://flybase.org/reports/FBgn0039078 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG4374 IPR013087:Zinc finger C2H2-type CG4374 11-Aug-17 DroID_v2017_08 - Scer\AZF1 - - Mmus\Zfp770 Hsap\ZNF770 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264750 CG44008 - http://flybase.org/reports/FBgn0264750 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from sequence model negative regulation of peptidase activity ; GO:0010466 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG31758, CG44008, CG42325" IPR002350:Kazal domain CG44008 11-Aug-17 DroID_v2017_08 "Drer\tmeff2a, Drer\tmeff1b, Drer\si:dkey-203a12.7, Drer\tmeff2b" - Cele\ZK813.6 Xtro\tmeff1 "Mmus\Tmeff2, Mmus\Tmeff1" "Hsap\TMEFF2, Hsap\TMEFF1" FBgn0085532 CG40894 - http://flybase.org/reports/FBgn0085532 protein_coding_gene - - - CG40894 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005301 mot-32l mottled 32l http://flybase.org/reports/FBgn0005301 - gene - - - mot-32l - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,female,temperature conditional" "pigment cell,temperature conditional" FBgn0263289 scrib scribbled http://flybase.org/reports/FBgn0263289 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with gukh "signal transduction ; GO:0007165 |... biological aspect of ancestor with PANTHER:PTN002351852 <> cell fate commitment involved in pattern specification ; GO:0060581 |... mutant phenotype <> regulation of synapse structure or activity ; GO:0050803 |... mutant phenotype <> cell proliferation ; GO:0008283 |... mutant phenotype <> compound eye development ; GO:0048749 |... mutant phenotype <> olfactory behavior ; GO:0042048 |... mutant phenotype <> cell fate specification ; GO:0001708 |... mutant phenotype <> negative regulation of epithelial cell proliferation ; GO:0050680 |... mutant phenotype <> dorsal closure ; GO:0007391 | traceable author statement <> establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | non-traceable author statement <> Malpighian tubule development ; GO:0072002 |... mutant phenotype <> dorsal closure ; GO:0007391 |... mutant phenotype <> memory ; GO:0007613 |... mutant phenotype <> establishment of ommatidial planar polarity ; GO:0042067 |... mutant phenotype <> cell morphogenesis ; GO:0000902 |... mutant phenotype <> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 |... mutant phenotype <> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 |... mutant phenotype <> negative regulation of cell proliferation ; GO:0008285 |... mutant phenotype <> wing disc morphogenesis ; GO:0007472 |... mutant phenotype <> zonula adherens assembly ; GO:0045186 |... mutant phenotype <> septate junction assembly ; GO:0019991 |... mutant phenotype <> regulation of endocytosis ; GO:0030100 |... mutant phenotype <> asymmetric protein localization ; GO:0008105 |... mutant phenotype <> regulation of Notch signaling pathway ; GO:0008593 |... mutant phenotype <> establishment of epithelial cell apical/basal polarity ; GO:0045198 |... mutant phenotype <> morphogenesis of larval imaginal disc epithelium ; GO:0016335 |... mutant phenotype <> stem cell differentiation ; GO:0048863 |... mutant phenotype <> establishment or maintenance of polarity of follicular epithelium ; GO:0016334 |... mutant phenotype <> negative regulation of imaginal disc growth ; GO:0045571 |... mutant phenotype <> R3/R4 cell fate commitment ; GO:0007464 |... mutant phenotype <> establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | traceable author statement <> maintenance of epithelial cell apical/basal polarity ; GO:0045199 |... biological aspect of ancestor with PANTHER:PTN002352077 <> morphogenesis of embryonic epithelium ; GO:0016331 | traceable author statement <> establishment or maintenance of polarity of larval imaginal disc epithelium ; GO:0016336 |... mutant phenotype <> establishment or maintenance of apical/basal cell polarity ; GO:0035088 |... mutant phenotype <> establishment or maintenance of polarity of embryonic epithelium ; GO:0016332 | traceable author statement <> stem cell proliferation ; GO:0072089 |... mutant phenotype <> morphogenesis of follicular epithelium ; GO:0016333 |... mutant phenotype <> regulation of cell cycle ; GO:0051726 | non-traceable author statement <> asymmetric protein localization ; GO:0008105 | traceable author statement <> negative regulation of cell proliferation ; GO:0008285 | traceable author statement <> morphogenesis of a polarized epithelium ; GO:0001738 | traceable author statement <> anterior/posterior axis specification, follicular epithelium ; GO:0030714 |... mutant phenotype <> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 |... mutant phenotype <> pole plasm protein localization ; GO:0007318 |... mutant phenotype <> ovarian follicle cell development ; GO:0030707 |... mutant phenotype <> regulation of JAK-STAT cascade ; GO:0046425 |... mutant phenotype" basolateral plasma membrane ; GO:0016323 | inferred from direct assay septate junction ; GO:0005918 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | traceable author statement septate junction ; GO:0005918 | traceable author statement septate junction ; GO:0005918 | non-traceable author statement neuromuscular junction ; GO:0031594 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay "scrib, Scrib, CG43398, scrb, CG5462, CG42614, smi97B, ird15, SCR, CT17324, ird, vart, l(3)673, l(3)j7B3, l(3)S042405, 0424/05, l(3)c00119, Scrb, Scb, MENE (3R)-F, CG5467, CG31082" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001478:PDZ domain, IPR001611:Leucine-rich repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR003591:Leucine-rich repeat, typical subtype" CG43398 11-Aug-17 DroID_v2017_08 "Drer\scrib, Drer\lrrc1" - "Cele\magi-1, Cele\Y42G9A.3, Cele\let-413" "Xtro\scrib, Xtro\lrrc1" "Mmus\Scrib, Mmus\Lrrd1, Mmus\Lrrc1, Mmus\Lrch4, Mmus\Tjp1" "Hsap\SCRIB, Hsap\LRRC1, Hsap\TJP1, Hsap\LRRD1, Hsap\LRCH4" " adult stage | female , adult stage , pupal stage , adult stage | male , larval stage | female , larval stage | male , embryonic stage | 0-24hr , embryonic stage | 0-6hr , larval stage , embryonic stage | 9-22hr , embryonic stage | late " " antennal segment 3

, antennal segment 2

, maxillary palpus

, adult brain | restricted

, organism

, Johnston's organ

" " embryonic stage | stage 16,17 , embryonic stage | stage 15,16 , embryonic stage | late , embryonic stage | 0-12hr , embryonic stage | mid-late , embryonic stage | early , adult stage , embryonic stage | mid , embryonic stage | stage 16-17 , embryonic stage | 12-24hr " " ventral nerve cord commissure

, pole cell

, cell body

, ventral nerve cord

, ventral midline

, embryonic sensory system

, embryonic peripheral nervous system

,

ubiquitous , protocerebrum

, neuroblast

, neuron

, longitudinal connective

, antenna

, embryonic central nervous system

, maxillary palpus

, gonad

, adult brain | restricted

" FBgn0265381 CR44322 - http://flybase.org/reports/FBgn0265381 non_protein_coding_gene - - - CR44322 - CR44322 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266769 CR45234 - http://flybase.org/reports/FBgn0266769 non_protein_coding_gene - - - "CR45234, lincRNA.599" - CR45234 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042164 CG18844 - http://flybase.org/reports/FBgn0042164 protein_coding_gene - - - CG18844 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261556 CG42674 - http://flybase.org/reports/FBgn0261556 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with RhoGEF2 imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with RhoGEF2 cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG7323, CG42674, CG13812, CG32223, CG42348, CG13811" "IPR011993:PH domain-like, IPR000219:Dbl homology (DH) domain" CG42674 11-Aug-17 DroID_v2017_08 "Drer\plekhg6, Drer\plekhg7, Drer\plekhg5a, Drer\plekhg5b" - Cele\rhgf-2 "Xtro\plekhg7, Xtro\plekhg5" "Mmus\Arhgef15, Mmus\Plekhg5, Mmus\Arhgef5, Mmus\Plekhg6, Mmus\Arhgef26" "Hsap\PLEKHG6, Hsap\PLEKHG5, Hsap\PLEKHG7" DRSC29701 K -0.325217914 0.709144588 -0.223212133 0.24194284 1.769260906 0.753322761 FBgn0085599 CG41284 - http://flybase.org/reports/FBgn0085599 protein_coding_gene - - - CG41284 "IPR004302:Cellulose/chitin-binding protein, N-terminal" CG41284 11-Aug-17 DroID_v2017_08 - - - - Mmus\Defb46 - FBgn0028279 l(1)G0419 lethal (1) G0419 http://flybase.org/reports/FBgn0028279 gene - - - l(1)G0419 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,melanotic mass phenotype,recessive" melanotic mass FBgn0065593 l(2)SH0896 lethal (2) SH0896 http://flybase.org/reports/FBgn0065593 gene - - - "l(2)SH0896, l(2)SH2 0896" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038153 Ir87a Ionotropic receptor 87a http://flybase.org/reports/FBgn0038153 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir87a, DmelIR87a, CG14376, IR87a" IPR001638:Solute-binding protein family 3/N-terminal domain of MltF CG14376 11-Aug-17 DroID_v2017_08 "Drer\LOC100537813, Drer\grid1b, Drer\grid1a" - Cele\glr-8 - "Mmus\Grik4, Mmus\Grid1" "Hsap\GRID1, Hsap\GRIK3" FBgn0054001 CG34001 - http://flybase.org/reports/FBgn0054001 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic sister chromatid cohesion ; GO:0007064 | inferred from biological aspect of ancestor with PANTHER:PTN002006636 Ctf18 RFC-like complex ; GO:0031390 | inferred from biological aspect of ancestor with PANTHER:PTN002006636 microtubule associated complex ; GO:0005875 | inferred from direct assay "BP1041, CG34001" IPR018607:Chromosome transmission fidelity protein 8 CG34001 11-Aug-17 DroID_v2017_08 Drer\chtf8 Scer\CTF8 Cele\T22C1.4 Xtro\chtf8 Mmus\Chtf8 Hsap\CHTF8 FBgn0270924 zf30C zinc finger protein 30C http://flybase.org/reports/FBgn0270924 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 neuron development ; GO:0048666 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG3998, zf30C, l(2)k02506, clone 1.52, anon-EST:Liang-1.52, Zf30c, zf30c, Zn30C, C282, Zf30C" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG3998 11-Aug-17 DroID_v2017_08 Drer\si:dkey-208k4.2 "Scer\PZF1, Scer\AZF1" "Cele\mep-1, Cele\eor-1, Cele\pzf-1" - "Mmus\Zfp658, Mmus\Gm14124, Mmus\Zfp780b, Mmus\Zfp974, Mmus\Zfp62" "Hsap\ZBTB24, Hsap\ZNF780B" DRSC03641 I -0.618223147 -1.88228469 -1.255933617 1.201817881 -0.564299946 -0.416789385 FBgn0029681 CG15239 - http://flybase.org/reports/FBgn0029681 protein_coding_gene - - - CG15239 IPR031941:Domain of unknown function DUF4773 CG15239 11-Aug-17 DroID_v2017_08 - - Cele\C09D4.2 - - - DRSC17972 IE 1.669979836 3.148961189 2.900650034 0.31237846 -0.541279407 0.611735101 FBgn0053262 CG33262 - http://flybase.org/reports/FBgn0053262 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33262 IPR006631:Protein of unknown function DM4/12 CG33262 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC22893 E 0.304340266 0.131397568 0.453693319 -1.573998141 -0.393832035 0.219280077 FBgn0035674 CG13295 - http://flybase.org/reports/FBgn0035674 protein_coding_gene - - - CG13295 "IPR027986:T-cell activation inhibitor, mitochondrial, IPR027989:Domain of unknown function DUF4461, IPR028031:Domain of unknown function DUF4460" CG13295 11-Aug-17 DroID_v2017_08 Drer\tcaim - Cele\C35B8.3 Xtro\tcaim Mmus\Tcaim Hsap\TCAIM "viable,fertile" FBgn0016647 ER3-5 ER3-5 http://flybase.org/reports/FBgn0016647 - gene - - - ER3-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266194 J29 - http://flybase.org/reports/FBgn0266194 gene - - - J29 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032149 CG4036 - http://flybase.org/reports/FBgn0032149 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005123 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 demethylation ; GO:0070988 | inferred from electronic annotation with InterPro:IPR032857 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype - CG4036 "IPR027450:Alpha-ketoglutarate-dependent dioxygenase AlkB-like, IPR032857:Alpha-ketoglutarate-dependent dioxygenase alkB homologue 4, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG4036 11-Aug-17 DroID_v2017_08 Drer\alkbh4 - Cele\F09F7.7 "Xtro\apex1, Xtro\alkbh4" "Mmus\Apex1, Mmus\Alkbh4" "Hsap\APEX1, Hsap\ALKBH4" viable FBgn0034295 CG10911 - http://flybase.org/reports/FBgn0034295 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.211, CG10911" IPR007931:Protein of unknown function DUF725 CG10911 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013229 E(var)181 E(var)181 http://flybase.org/reports/FBgn0013229 - gene - - - E(var)181 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0010180 tu(2)59h tu(2)59h http://flybase.org/reports/FBgn0010180 - gene - - - tu(2)59h - - 11-Aug-17 DroID_v2017_08 - - - - - - melanotic mass phenotype FBgn0002356 l(3)87Ec lethal (3) 87Ec http://flybase.org/reports/FBgn0002356 - gene - - - "c9a, C9a, l(3)C9a, l(3)c9a, l(3)87Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - "non-enhancer of variegation,non-suppressor of variegation,lethal,recessive" FBgn0033204 CG2065 - http://flybase.org/reports/FBgn0033204 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - - CG2065 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG2065 11-Aug-17 DroID_v2017_08 "Drer\cbr1, Drer\si:ch211-107o10.3, Drer\rdh12l, Drer\dhrs13l1, Drer\dhrsx, Drer\si:ch211-165b10.3, Drer\si:dkey-23o4.6, Drer\ascc1, Drer\si:dkey-94e7.2, Drer\si:dkey-174n20.1, Drer\rdh14b, Drer\zgc:112332, Drer\flj13639, Drer\zgc:153441, Drer\dhrs13a.2, Drer\dhrs13a.3, Drer\dhrs13a.1, Drer\si:dkey-73n8.3, Drer\zgc:64106, Drer\rdh12, Drer\rdh14a, Drer\dhrs12, Drer\cbr1l" "Scer\ENV9, Scer\GPI11, Scer\YNL181W, Scer\YKL107W" "Cele\E04F6.15, Cele\DC2.5, Cele\K10H10.6, Cele\C27D8.4, Cele\dhs-22" "Xtro\rdh11, Xtro\ascc1, Xtro\dhrsx, Xtro\dhrs12, Xtro\rdh14, Xtro\dhrs13, Xtro\rdh13" "Mmus\Cbr1, Mmus\1700003E16Rik, Mmus\Ascc1, Mmus\Wwox, Mmus\Rdh11, Mmus\Dhrs13, Mmus\Rdh14, Mmus\Dhrsx, Mmus\Rdh13, Mmus\Rdh12, Mmus\Cbr3" "Hsap\RDH14, Hsap\DHRS13, Hsap\CBR3, Hsap\OSTC, Hsap\RDH11, Hsap\DHRS12, Hsap\CBR1, Hsap\C2orf81, Hsap\DHRSX, Hsap\RDH12, Hsap\RDH13" viable DRSC21328 K 0.274157004 0.931060458 -0.21244034 0.435516919 1.524758674 -1.117257957 FBgn0260107 2L2806 - http://flybase.org/reports/FBgn0260107 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L2806 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0265105 CR44207 - http://flybase.org/reports/FBgn0265105 non_protein_coding_gene - - - CR44207 - CR44207 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002187 l(3)62Da lethal (3) 62Da http://flybase.org/reports/FBgn0002187 - gene - - - "dre10, l(3)Da, l(3)dre10, l(3)62Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0029172 Fad2 Fad2 http://flybase.org/reports/FBgn0029172 protein_coding_gene "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water ; GO:0016717 | inferred from electronic annotation with InterPro:IPR015876" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015876 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype courtship behavior ; GO:0007619 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype pheromone metabolic process ; GO:0042810 | inferred from mutant phenotype - "fad2, CG7923, fad, Fad2, desatF, desatF-alpha" "IPR001522:Fatty acid desaturase type 1, conserved site, IPR005804:Fatty acid desaturase domain, IPR015876:Acyl-CoA desaturase" CG7923 11-Aug-17 DroID_v2017_08 "Drer\scdb, Drer\scd" Scer\OLE1 "Cele\fat-5, Cele\fat-7, Cele\fat-6" Xtro\scd "Mmus\Scd2, Mmus\Scd4, Mmus\Scd1, Mmus\Scd3" "Hsap\SCD5, Hsap\SCD" "viable,visible,courtship behavior defective,mating defective" "trichogen cell,supernumerary,tormogen cell" DRSC11165 EK -0.152125597 -1.494320768 0.558777411 -2.763099657 -3.609312831 -2.579902426 FBgn0043550 Tsp68C Tetraspanin 68C http://flybase.org/reports/FBgn0043550 protein_coding_gene molecular_function ; GO:0003674 | no biological data available hemopoiesis ; GO:0030097 | inferred from genetic interaction with ytr lateral inhibition ; GO:0046331 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 trans-Golgi network ; GO:0005802 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "Dm.Tsp68C, CG32136, Tsp68C, Tsp68c" "IPR018499:Tetraspanin/Peripherin, IPR008952:Tetraspanin, EC2 domain" CG32136 11-Aug-17 DroID_v2017_08 - - - Xtro\cd151 - Hsap\TSPAN11 "viable,fertile,visible" "chaeta,supernumerary,trichogen cell,tormogen cell,lamellocyte,embryonic/larval hemocyte" FBgn0031116 CG1695 - http://flybase.org/reports/FBgn0031116 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG1695 "IPR000195:Rab-GTPase-TBC domain, IPR004012:RUN domain" CG1695 11-Aug-17 DroID_v2017_08 "Drer\sgsm1b, Drer\sgsm2, Drer\sgsm1a" Scer\GYP7 Cele\tbc-8 "Xtro\sgsm2, Xtro\sgsm1" "Mmus\Sgsm1, Mmus\Sgsm2" "Hsap\SGSM2, Hsap\SGSM1" viable FBgn0023009 l(3)S101804 lethal (3) S101804 http://flybase.org/reports/FBgn0023009 - gene - - - "1018/04, l(3)S101804" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0034841 CG13541 - http://flybase.org/reports/FBgn0034841 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13541 - CG13541 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036217 CG5906 - http://flybase.org/reports/FBgn0036217 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 "BcDNA:AT16953, CG5906" IPR007248:Mpv17/PMP22 CG5906 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-120k19.1, Drer\mpv17l2, Drer\pxmp2, Drer\mpv17" "Scer\YOR292C, Scer\SYM1" Cele\ZK470.1 "Xtro\mpv17l2, Xtro\pxmp2" "Mmus\Pxmp2, Mmus\Mpv17, Mmus\Mpv17l2, Mmus\Mpv17l" "Hsap\MPV17L, Hsap\PXMP2, Hsap\MPV17L2, Hsap\MPV17" viable FBgn0016730 Rst(2)chl Resistant to chlorpyrifos http://flybase.org/reports/FBgn0016730 - gene - - - Rst(2)chl - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0045841 betaTub56D::betaTub85D betaTub56D::betaTub85D http://flybase.org/reports/FBgn0045841 engineered_fusion_gene - - - betaTub56D::betaTub85D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061078 l(3)S014917b lethal (3) S014917b http://flybase.org/reports/FBgn0061078 gene - - - "0149/17, l(3)S014917b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0001456 l(1)7Dj lethal (1) 7Dj http://flybase.org/reports/FBgn0001456 - gene - - - l(1)7Dj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0013689 mt:tRNA:Ala-TGC mitochondrial transfer RNA:Alanine-TGC http://flybase.org/reports/FBgn0013689 FBgn0002867 tRNA_gene - - - "CR34077, Dm mt tRNA[Ala], mtdbD00006302, mt:tRNA:Ala-TGC, mt:tRNA:A, tRNA[Ala]" - CR34077 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065099 snRNA:7SK small nuclear RNA 7SK http://flybase.org/reports/FBgn0065099 snRNA_gene - - - "snmRNA:331, CR33925, Dm-331, d7SK, snRNA:7SK, snmRNA:331-RA, 7SK snRNA, 7SK RNA, 7SK, chr3R:3300517..3300757" - CR33925 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037020 Pex14 Peroxin 14 http://flybase.org/reports/FBgn0037020 protein_coding_gene receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000551635 "protein import into peroxisome matrix, docking ; GO:0016560 | inferred from biological aspect of ancestor with PANTHER:PTN000551635 protein targeting to peroxisome ; GO:0006625 | inferred from sequence or structural similarity with HGNC:8856,SGD:S000003121 peroxisome organization ; GO:0007031 | inferred from mutant phenotype" "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8856 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:8856,SGD:S000003121 peroxisomal importomer complex ; GO:1990429 | inferred from biological aspect of ancestor with PANTHER:PTN000551635 peroxisomal membrane ; GO:0005778 | inferred from biological aspect of ancestor with PANTHER:PTN000551635" "CG4289, Pex14, DmelPex14, PEX14" "IPR025655:Peroxisomal membrane protein 14, IPR006785:Peroxisome membrane anchor protein Pex14p, N-terminal" CG4289 11-Aug-17 DroID_v2017_08 Drer\pex14 Scer\PEX14 Cele\prx-14 Xtro\pex14 Mmus\Pex14 Hsap\PEX14 viable FBgn0036988 CG5262 - http://flybase.org/reports/FBgn0036988 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.347, CG5262" "IPR013057:Amino acid transporter, transmembrane domain" CG5262 11-Aug-17 DroID_v2017_08 Drer\tmem104 - Cele\C03A3.2 Xtro\tmem104 Mmus\Tmem104 Hsap\TMEM104 viable FBgn0037235 CG1103 - http://flybase.org/reports/FBgn0037235 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG1103, anon-WO0118547.152" IPR026748:Clarin CG1103 11-Aug-17 DroID_v2017_08 "Drer\clrn1, Drer\clrn2, Drer\clrn3" - Cele\Y67D8C.22 - "Mmus\Clrn3, Mmus\Clrn1, Mmus\Clrn2" "Hsap\CLRN3, Hsap\CLRN1, Hsap\CLRN2" DRSC24616 K -2.193477536 0.118010086 FBgn0044381 anon-5.9 anon-5.9 http://flybase.org/reports/FBgn0044381 repeat_region - - - anon-5.9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264462 CR43870 - http://flybase.org/reports/FBgn0264462 non_protein_coding_gene - - - CR43870 - CR43870 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264256 naz nazgul http://flybase.org/reports/FBgn0264256 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from direct assay "Naz, naz" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062661 EP3223 EP3223 http://flybase.org/reports/FBgn0062661 gene - - - "EP(3)3223, EP3223" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083259 E(smoDN)871 Enhancer of smoDN 871 http://flybase.org/reports/FBgn0083259 gene - - - E(smoDN)871 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053364 5SrRNA:CR33364 5SrRNA:CR33364 http://flybase.org/reports/FBgn0053364 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33364, 5SrRNA:CR33364" - CR33364 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003402 Shudderer Shudderer http://flybase.org/reports/FBgn0003402 - gene - - - "Shudderer, Shu" - - 11-Aug-17 DroID_v2017_08 - - - - - - "uncoordinated,gravitaxis defective" FBgn0259247 laccase2 laccase 2 http://flybase.org/reports/FBgn0259247 protein_coding_gene "copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR002355, InterPro:IPR011706, InterPro:IPR011707 ferroxidase activity ; GO:0004322 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 iron ion transmembrane transporter activity ; GO:0005381 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001709969" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001117, InterPro:IPR011706 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype iron ion transport ; GO:0006826 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 iron assimilation by reduction and transport ; GO:0033215 | inferred from biological aspect of ancestor with PANTHER:PTN001709969" high-affinity iron permease complex ; GO:0033573 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 "laccase2, CG42345, CG10408, CG10398, CG30437, CG32838, MCO2" "IPR001117:Multicopper oxidase, type 1, IPR002355:Multicopper oxidase, copper-binding site, IPR008972:Cupredoxin, IPR011706:Multicopper oxidase, type 2, IPR011707:Multicopper oxidase, type 3, IPR033138:Multicopper oxidases, conserved site" CG42345 11-Aug-17 DroID_v2017_08 "Drer\hephl1b, Drer\cp" "Scer\GMC1, Scer\FET3, Scer\FET5" Cele\F21D5.3 Xtro\hephl1 "Mmus\Hephl1, Mmus\Cp, Mmus\Heph" "Hsap\HEPH, Hsap\CP, Hsap\HEPHL1" DRSC26018 K -0.480722888 0.331649162 0.434171433 0.428054987 2.307090213 0.508630512 FBgn0266158 CR44864 - http://flybase.org/reports/FBgn0266158 non_protein_coding_gene - - - CR44864 - CR44864 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083300 E(smoDN)1823 Enhancer of smoDN 1823 http://flybase.org/reports/FBgn0083300 gene - - - E(smoDN)1823 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061196 CG15468 - http://flybase.org/reports/FBgn0061196 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15468, SIP3" IPR031883:Protein of unknown function DUF4763 CG15468 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC18051 K -0.296428581 0.483790754 -0.315684127 0.350809764 2.246247079 1.091342566 FBgn0069327 X-146-21 X-146-21 http://flybase.org/reports/FBgn0069327 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-146-21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0019986 Glt::Nrt Glt::Nrt http://flybase.org/reports/FBgn0019986 - engineered_fusion_gene - - - Glt::Nrt - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025836 RhoGAP1A Rho GTPase activating protein at 1A http://flybase.org/reports/FBgn0025836 FBgn0026442 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN001142599 Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with RhoGEF4 positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with RhoGEF4 positive regulation of GTPase activity ; GO:0043547 | inferred from biological aspect of ancestor with PANTHER:PTN001142599 Golgi organization ; GO:0007030 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001142599 "CG40494, EG:23E12.2, CG17960, EG:23E12.5, CG17617, BCR, CG40453, RhoGAP1A, rhoGAP1A, RhoGAP" "IPR000198:Rho GTPase-activating protein domain, IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR008936:Rho GTPase activation protein, IPR000008:C2 domain, IPR011993:PH domain-like" CG40494 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-33c9.6, Drer\arhgap9, Drer\arhgap33, Drer\arhgap21b, Drer\si:ch211-253h3.1, Drer\arhgap23a, Drer\arhgap12a, Drer\arhgap31, Drer\bcr, Drer\arhgap32a, Drer\arhgap10, Drer\arhgap29a, Drer\arhgap27l, Drer\arhgap32b, Drer\arhgap15, Drer\chn2, Drer\si:dkey-91m11.5, Drer\LOC560371" "Scer\RGA1, Scer\BEM2, Scer\BEM3, Scer\RGD1, Scer\RGA2" "Cele\rrc-1, Cele\exc-5, Cele\spv-1, Cele\chin-1, Cele\tag-325, Cele\T04C9.1, Cele\rga-1, Cele\pac-1" "Xtro\arhgap26, Xtro\arhgap27, Xtro\bcr, Xtro\arhgap21, Xtro\abr" "Mmus\Arhgap9, Mmus\Arhgap33, Mmus\Chn2, Mmus\Bcr, Mmus\Abr, Mmus\Arhgap26, Mmus\Arhgap32, Mmus\Arhgap42, Mmus\Arhgap31, Mmus\Arhgap15, Mmus\Arhgap29, Mmus\Arhgap23, Mmus\Chn1, Mmus\Arhgap10, Mmus\Arhgap21, Mmus\Arhgap27" "Hsap\CHN1, Hsap\ARHGAP31, Hsap\ARHGAP42, Hsap\ARHGAP32, Hsap\ARHGAP9, Hsap\ABR, Hsap\ARHGAP23, Hsap\ARHGAP27, Hsap\ARHGAP26, Hsap\ARHGAP21, Hsap\ARHGAP33, Hsap\BCR, Hsap\ARHGAP29, Hsap\CHN2, Hsap\ARHGAP15, Hsap\ARHGAP10" viable FBgn0005216 l(3)ET7 lethal Elaine Tasaka 7 http://flybase.org/reports/FBgn0005216 - gene - - - l(3)ET7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cold sensitive,heat sensitive,male sterile" FBgn0058115 CG40115 - http://flybase.org/reports/FBgn0058115 protein_coding_gene - - - CG40115 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058241 CG40241 - http://flybase.org/reports/FBgn0058241 protein_coding_gene - - - CG40241 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045855 e(Pi3K92E)gamma e(Pi3K92E)gamma http://flybase.org/reports/FBgn0045855 gene - - - "gamma, e(Pi3K92E)gamma" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002255 l(3)68Eg lethal (3) 68Eg http://flybase.org/reports/FBgn0002255 - gene - - - "rsg17, l(3)rsg17, l(3)68Eg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037482 CG10055 - http://flybase.org/reports/FBgn0037482 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000311574 box H/ACA snoRNP assembly ; GO:0000493 | inferred from biological aspect of ancestor with PANTHER:PTN000311574 ribonucleoprotein complex assembly ; GO:0022618 | inferred from sequence or structural similarity with UniProtKB:Q6PI26 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN000311574 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000311574 "RE52393, CG10055" "IPR007009:SHQ1 protein, IPR015943:WD40/YVTN repeat-like-containing domain" CG10055 11-Aug-17 DroID_v2017_08 Drer\shq1 Scer\SHQ1 Cele\Y48A5A.1 Xtro\shq1 Mmus\Shq1 Hsap\SHQ1 viable FBgn0033374 CG13741 - http://flybase.org/reports/FBgn0033374 protein_coding_gene - - - "CG30346, CG13741" - CG13741 11-Aug-17 DroID_v2017_08 - - - - - - "visible,planar polarity defective,partially lethal - majority die,some die during pupal stage,female sterile" trichogen cell DRSC06412 K 0.335951901 0.588919752 0.262231959 0.200083419 3.851150831 1.058683071 FBgn0003272 rp rotated penis http://flybase.org/reports/FBgn0003272 - gene - - - rp - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,small body" "tergite,eye,leg,abdomen,male genitalia" FBgn0004091 l(2)60Cc lethal (2) 60Cc http://flybase.org/reports/FBgn0004091 - gene - - - l(2)60Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005361 sx sexcombless http://flybase.org/reports/FBgn0005361 - gene - - - sx - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "genitalia,clasper,penis,sex comb,macrochaeta,vulva,gonopod thorn bristle,anal plate,ovary,testis,metatarsus" FBgn0267768 CR46099 - http://flybase.org/reports/FBgn0267768 non_protein_coding_gene - - - CR46099 - CR46099 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005135 l(1)Y107 lethal (1) Y107 http://flybase.org/reports/FBgn0005135 - gene - - - l(1)Y107 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0001377 l(1)2Bh lethal (1) 2Bh http://flybase.org/reports/FBgn0001377 - gene - - - "HM40, l(1)HM40, l(1)2Bh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086066 snoRNA:Me5.8S-G74 - http://flybase.org/reports/FBgn0086066 snoRNA_gene - - - "snoRNA:Me5.8S-G74, Me5.8S-Gm74, Me5.8S-G74, CR34695" - CR34695 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033467 CG15863 - http://flybase.org/reports/FBgn0033467 protein_coding_gene - - - CG15863 IPR030482:p53 and DNA damage-regulated protein 1 CG15863 11-Aug-17 DroID_v2017_08 Drer\pdrg1 - Cele\T07D4.5 Xtro\pdrg1 Mmus\Pdrg1 Hsap\PDRG1 FBgn0267778 CR46109 - http://flybase.org/reports/FBgn0267778 non_protein_coding_gene - - - CR46109 - CR46109 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040352 CG14416 - http://flybase.org/reports/FBgn0040352 protein_coding_gene - - - "EG:BACR43E12.7, CG14416" - CG14416 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065129 l(3)SH134 lethal (3) SH134 http://flybase.org/reports/FBgn0065129 gene - - - "l(3)SH134, l(2)SH3 134" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267532 CR45872 - http://flybase.org/reports/FBgn0267532 non_protein_coding_gene - - - CR45872 - CR45872 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022815 E(faf)E1051 Enhancer of faf E1051 http://flybase.org/reports/FBgn0022815 - gene - - - E(faf)E1051 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022380 Pt-10A Adult protein-10A http://flybase.org/reports/FBgn0022380 - gene - - - Pt-10A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065222 l(2)SH2226 lethal (2) SH2226 http://flybase.org/reports/FBgn0065222 gene - - - "l(2)SH2226, l(2)SH2 2226" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016764 anon-17Ca anon-17Ca http://flybase.org/reports/FBgn0016764 - gene - - - "C1, anon-17Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0023170 RpL39 Ribosomal protein L39 http://flybase.org/reports/FBgn0023170 FBgn0047027 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000077, InterPro:IPR020083 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000463054 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000077, InterPro:IPR020083 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000077, InterPro:IPR020083 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "RpL46, L39, RPl46, Rp46, rp46, anon-EST:Posey16, CG3997, BcDNA:RH27094, RpL39" "IPR020083:Ribosomal protein L39e, conserved site, IPR000077:Ribosomal protein L39e, IPR023626:Ribosomal protein L39e domain" CG3997 11-Aug-17 DroID_v2017_08 Drer\rpl39 Scer\RPL39 Cele\rpl-39 Xtro\rpl39 "Mmus\Rpl39l, Mmus\Rpl39" "Hsap\RPL39, Hsap\RPL39L" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "lethal - all die before end of pupal stage,some die during pupal stage" DRSC04651 IEK -2.2505861 -2.415181306 3.139503081 -4.523638653 2.810435677 2.640578618 FBgn0010241 Mdr50 Multi drug resistance 50 http://flybase.org/reports/FBgn0010241 "FBtr0087537, FBpp0086666" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 xenobiotic-transporting ATPase activity ; GO:0008559 | inferred from sequence or structural similarity with UniProtKB:Q00748 efflux transmembrane transporter activity ; GO:0015562 | inferred from sequence or structural similarity with UniProtKB:Q00748" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 response to toxic substance ; GO:0009636 | inferred from expression pattern xenobiotic transport ; GO:0042908 | inferred from sequence or structural similarity with UniProtKB:Q00748 renal tubular secretion ; GO:0097254 | inferred from expression pattern ATP-binding cassette (ABC) transporter complex ; GO:0043190 | inferred from sequence or structural similarity with UniProtKB:Q00748 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q00748 "CG8523, MDR50, Dm3, Dm2, Mdr50, mdr50" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8523 11-Aug-17 DroID_v2017_08 "Drer\abcb4, Drer\abcb11a, Drer\abcb9, Drer\abcb3l1, Drer\abcb5, Drer\abcb10, Drer\abcb11b, Drer\abcb8" Scer\STE6 "Cele\haf-3, Cele\haf-2, Cele\haf-4, Cele\haf-9, Cele\pgp-1, Cele\pgp-2, Cele\pgp-11, Cele\pgp-10, Cele\pgp-3, Cele\haf-1, Cele\pgp-6, Cele\haf-6, Cele\haf-8, Cele\pgp-9, Cele\pgp-7, Cele\pgp-5, Cele\pgp-14, Cele\haf-7, Cele\pgp-13, Cele\pgp-8, Cele\pgp-12, Cele\pgp-4" "Xtro\LOC100496268, Xtro\LOC100494740, Xtro\abcb8" "Mmus\Abcb5, Mmus\Abcb9, Mmus\Abcb8, Mmus\Abcb11, Mmus\Abcb10, Mmus\Abcb1a, Mmus\Abcb1b, Mmus\Abcb4" "Hsap\ABCB10, Hsap\ABCB11, Hsap\ABCB1, Hsap\ABCB8, Hsap\ABCB5, Hsap\ABCB4" adult stage DRSC07467 IE 1.981677106 0.106965008 2.428400612 0.396501141 -0.250017016 0.060573317 FBgn0002908 mus311 mutagen-sensitive 311 http://flybase.org/reports/FBgn0002908 - gene - - - mus311 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,female sterile,DNA repair defective" FBgn0266836 CR45298 - http://flybase.org/reports/FBgn0266836 non_protein_coding_gene - - - CR45298 - CR45298 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264430 CR43848 - http://flybase.org/reports/FBgn0264430 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR43848 - CR43848 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060553 l(3)S097613b lethal (3) S097613b http://flybase.org/reports/FBgn0060553 gene - - - "0976/13, l(3)S097613b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260309 GSd411 - http://flybase.org/reports/FBgn0260309 gene - - - GSd411 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0000876 fs(1)M74 female sterile (1) M74 http://flybase.org/reports/FBgn0000876 - gene - - - fs(1)M74 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0261931 CG42797 - http://flybase.org/reports/FBgn0261931 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from sequence or structural similarity with Nedd4 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with Nedd4 cellular_component ; GO:0005575 | no biological data available "CG3099, CG42797, CG3003, BT058014.1" "IPR001202:WW domain, IPR000569:HECT domain" CG42797 11-Aug-17 DroID_v2017_08 "Drer\hecw1b, Drer\LOC100334952, Drer\LOC100534749, Drer\yap1, Drer\itcha, Drer\bag3, Drer\wwtr1, Drer\hecw2a, Drer\nedd4a, Drer\smurf2, Drer\LOC103909734, Drer\nedd4l, Drer\hecw2b, Drer\smurf1, Drer\wwp2" "Scer\RSP5, Scer\TOM1" Cele\hecw-1 "Xtro\bag3, Xtro\itch, Xtro\hecw1, Xtro\smurf1, Xtro\wwp2, Xtro\nedd4, Xtro\nedd4l" "Mmus\Yap1, Mmus\Bag3, Mmus\Hecw2, Mmus\Smurf2, Mmus\Gas7, Mmus\Nedd4l, Mmus\Smurf1, Mmus\Nedd4, Mmus\Hecw1, Mmus\Wwp1, Mmus\Itch, Mmus\Wwp2" "Hsap\HECW2, Hsap\NEDD4, Hsap\SMURF2, Hsap\GAS7, Hsap\WWP2, Hsap\HECW1, Hsap\WWP1, Hsap\SMURF1, Hsap\BAG3, Hsap\ITCH, Hsap\YAP1, Hsap\NEDD4L" FBgn0052625 CG32625 - http://flybase.org/reports/FBgn0052625 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32625 "IPR022776:TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG32625 11-Aug-17 DroID_v2017_08 "Drer\zgc:56699, Drer\LOC100535654" - Cele\T06A10.3 Xtro\LOC100145274 "Mmus\BC048502, Mmus\Zfp850, Mmus\Gtsf1l, Mmus\Gtsf1" "Hsap\GTSF1, Hsap\GTSF1L" "viable,fertile" FBgn0065421 l(2)SH1522 lethal (2) SH1522 http://flybase.org/reports/FBgn0065421 gene - - - "l(2)SH1522, l(2)SH2 1522" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082629 S(CycE[JP])2.9 S(CycE[JP])2.9 http://flybase.org/reports/FBgn0082629 gene - - - S(CycE[JP])2.9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040136 l(1)G0498 lethal (1) G0498 http://flybase.org/reports/FBgn0040136 gene - - - l(1)G0498 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,male,female,lethal,recessive" FBgn0037702 CG8176 - http://flybase.org/reports/FBgn0037702 protein_coding_gene phospholipid binding ; GO:0005543 | inferred from sequence model AP-2 adaptor complex binding ; GO:0035612 | inferred from sequence or structural similarity with HGNC:29002 clathrin-dependent endocytosis ; GO:0072583 | inferred from sequence or structural similarity with HGNC:29002 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:29002 clathrin-coated pit ; GO:0005905 | inferred from sequence or structural similarity with HGNC:29002 cytoplasm ; GO:0005737 | inferred from direct assay "CG31123, CG8176, FCHo2, FCHo" "IPR001060:FCH domain, IPR018808:Muniscin C-terminal, IPR028565:Mu homology domain, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR031160:F-BAR domain" CG8176 11-Aug-17 DroID_v2017_08 "Drer\pstpip2, Drer\sgip1a, Drer\pstpip1b, Drer\fcho1, Drer\gas7a, Drer\fcho2, Drer\pstpip1a, Drer\gas7b, Drer\sgip1b" "Scer\RGD2, Scer\HOF1" Cele\fcho-1 "Xtro\sgip1, Xtro\fcho1, Xtro\fcho2" "Mmus\Fcho2, Mmus\Pstpip2, Mmus\Gas7, Mmus\Sgip1, Mmus\Pstpip1, Mmus\Fcho1" "Hsap\PSTPIP2, Hsap\SGIP1, Hsap\FCHO2, Hsap\GAS7, Hsap\FCHO1, Hsap\PSTPIP1" "viable,fertile,visible" tormogen cell FBgn0035942 ValRS-m "Valyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0035942 protein_coding_gene "valine-tRNA ligase activity ; GO:0004832 | inferred from electronic annotation with InterPro:IPR002303 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002300, InterPro:IPR002303, InterPro:IPR009080 aminoacyl-tRNA editing activity ; GO:0002161 | inferred from electronic annotation with InterPro:IPR009008 valine-tRNA ligase activity ; GO:0004832 | traceable author statement" valyl-tRNA aminoacylation ; GO:0006438 | inferred from electronic annotation with InterPro:IPR002303 valyl-tRNA aminoacylation ; GO:0006438 | traceable author statement mitochondrion ; GO:0005739 | traceable author statement "CG5660, ValRS-m" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002300:Aminoacyl-tRNA synthetase, class Ia, IPR002303:Valine-tRNA ligase, IPR009008:Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR013155:Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR033705:Valyl tRNA synthetase, anticodon-binding domain" CG5660 11-Aug-17 DroID_v2017_08 "Drer\vars, Drer\vars2" Scer\VAS1 "Cele\vars-1, Cele\glp-4" Xtro\vars2 "Mmus\Vars, Mmus\Vars2" "Hsap\VARS, Hsap\VARS2" "viable,visible" trichogen cell FBgn0011569 can cannonball http://flybase.org/reports/FBgn0011569 FBgn0036079 protein_coding_gene - spermatid differentiation ; GO:0048515 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11539 inferred from sequence or structural similarity with HGNC:17304 inferred from sequence or structural similarity with SGD:S000000402 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype male meiosis I ; GO:0007141 | inferred from mutant phenotype spermatid development ; GO:0007286 | traceable author statement meiotic nuclear division ; GO:0007126 | traceable author statement nucleolus ; GO:0005730 | inferred from direct assay male germ cell nucleus ; GO:0001673 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11539 inferred from sequence or structural similarity with HGNC:17304 inferred from sequence or structural similarity with SGD:S000000402 "dTAF5L, dTAF[[II]]80, dmTAF5b, TAF5L, CG6577, can, Can, Taf5L, WSB-1" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR007582:TFIID subunit TAF5, NTD2 domain, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG6577 11-Aug-17 DroID_v2017_08 "Drer\taf5l, Drer\taf5" Scer\TAF5 Cele\taf-5 "Xtro\taf5l, Xtro\taf5" "Mmus\Taf5, Mmus\Wdr38, Mmus\Taf5l" "Hsap\TAF5, Hsap\TAF5L" "male sterile,recessive,meiotic cell cycle defective,viable" "testis,spermatocyte" FBgn0260764 CG42562 - http://flybase.org/reports/FBgn0260764 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14481, CG42562" - CG42562 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259531 B2005 - http://flybase.org/reports/FBgn0259531 gene - - - B2005 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,tarsal segment,tibia,arista" FBgn0052121 CG32121 - http://flybase.org/reports/FBgn0052121 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 CG32121 "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type" CG32121 11-Aug-17 DroID_v2017_08 - - - - Mmus\Zbtb3 "Hsap\ZBTB12, Hsap\ZBTB24, Hsap\ZBTB9, Hsap\ZBTB49, Hsap\ZNF131" lethal FBgn0028883 CG4959 - http://flybase.org/reports/FBgn0028883 protein_coding_gene - - - "bs04e09.y1, BG:DS04095.3, BcDNA:GH21762, CG4959" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC01938 K 0.787960895 0.540336643 -0.685209612 0.114267074 1.8736043 0.595796613 FBgn0028578 pjc-16 pjc-16 http://flybase.org/reports/FBgn0028578 gene - - - pjc-16 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050110 CG30110 - http://flybase.org/reports/FBgn0050110 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs09e07, CG30110" - CG30110 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC05686 I -1.529531705 -0.53450013 0.009128057 -0.174505015 -0.286136893 -0.310439807 FBgn0065362 l(2)SH1742 lethal (2) SH1742 http://flybase.org/reports/FBgn0065362 gene - - - "l(2)SH1742, l(2)SH2 1742" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026679 IntS4 Integrator 4 http://flybase.org/reports/FBgn0026679 FBgn0030047 protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA processing ; GO:0016180 | inferred from mutant phenotype snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:25048 neurogenesis ; GO:0022008 | inferred from mutant phenotype snRNA 3'-end processing ; GO:0034472 | inferred from direct assay integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:25048 integrator complex ; GO:0032039 | inferred from biological aspect of ancestor with PANTHER:PTN000468509 "CG12113, IntS4, Int4, l(1)G0095" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG12113 11-Aug-17 DroID_v2017_08 Drer\ints4 - Cele\W04A4.5 Xtro\ints4 Mmus\Ints4 Hsap\INTS4 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0267464 CR45814 - http://flybase.org/reports/FBgn0267464 non_protein_coding_gene - - - CR45814 - CR45814 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004663 ms(1)10A male sterile (1) 10A http://flybase.org/reports/FBgn0004663 "FBgn0002798, FBgn0002811" gene - - - "ms(1)BP6, ms(1)10A" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile axoneme FBgn0003723 tonomacrochaetae tonomacrochaetae http://flybase.org/reports/FBgn0003723 - gene - - - "tmc, tonomacrochaetae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" "macrochaeta,adult abdomen" FBgn0267622 CR45960 - http://flybase.org/reports/FBgn0267622 non_protein_coding_gene - - - CR45960 - CR45960 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264661 small-potatoes small potatoes http://flybase.org/reports/FBgn0264661 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - small-potatoes - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,embryonic/larval dorsal trunk" FBgn0035996 CG3448 - http://flybase.org/reports/FBgn0035996 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR010585, InterPro:IPR014751" "DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR010585, InterPro:IPR014751 double-strand break repair ; GO:0006302 | inferred from electronic annotation with InterPro:IPR010585, InterPro:IPR014751" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR010585 CG3448 IPR010585:DNA repair protein XRCC4 CG3448 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015547 srg semirough http://flybase.org/reports/FBgn0015547 - gene - - - srg - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0005729 l(1)TK205 lethal (1) TK205 http://flybase.org/reports/FBgn0005729 - gene - - - "l205, l(1)TK205" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0037181 CG11370 - http://flybase.org/reports/FBgn0037181 protein_coding_gene - - - CG11370 - CG11370 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0259841 Su(Ste):CR42410 Su(Ste):CR42410 http://flybase.org/reports/FBgn0259841 non_protein_coding_gene - - - "Su(Ste):CR42410, CR42410" - CR42410 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001945 l(2)26Cf lethal (2) 26Cf http://flybase.org/reports/FBgn0001945 - gene - - - "l(2)gdh-13, l(2)26Cf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003420 slc slim chaetae http://flybase.org/reports/FBgn0003420 - gene - - - "l(1)3Ea, slc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" "macrochaeta,wing" FBgn0259457 EP-111 - http://flybase.org/reports/FBgn0259457 gene - - - EP-111 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0264342 CG43798 - http://flybase.org/reports/FBgn0264342 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43798, lincRNA.43" - CG43798 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083011 snoRNA:Psi28S-1135b snoRNA:Psi28S-1135b http://flybase.org/reports/FBgn0083011 snoRNA_gene - - - "snoRNA:Psi28S-1135b, Psi28S-1135b, psi28S-1135b, CR34605" - CR34605 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000582 eq equational producer http://flybase.org/reports/FBgn0000582 - gene - - - eq - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" FBgn0029980 CG10778 - http://flybase.org/reports/FBgn0029980 protein_coding_gene polyprenyltransferase activity ; GO:0002094 | inferred from biological aspect of ancestor with PANTHER:PTN000033324 phagocytosis ; GO:0006909 | inferred from mutant phenotype polyprenol biosynthetic process ; GO:0016094 | inferred from biological aspect of ancestor with PANTHER:PTN000033324 - CG10778 "IPR001441:Decaprenyl diphosphate synthase-like, IPR018520:Di-trans-poly-cis-decaprenylcistransferase-like, conserved site" CG10778 11-Aug-17 DroID_v2017_08 Drer\dhdds "Scer\RER2, Scer\SRT1" Cele\T01G1.4 Xtro\dhdds Mmus\Dhdds Hsap\DHDDS "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0003184 qf quetas finas http://flybase.org/reports/FBgn0003184 - gene - - - qf - - 11-Aug-17 DroID_v2017_08 - - - - - - "semi-sterile,viable" "microchaeta,macrochaeta" FBgn0039158 CG6182 - http://flybase.org/reports/FBgn0039158 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 - "BcDNA:LD17019, CG6182" IPR000195:Rab-GTPase-TBC domain CG6182 11-Aug-17 DroID_v2017_08 Drer\tbc1d7 - - Xtro\tbc1d7 Mmus\Tbc1d7 "Hsap\TBC1D7, Hsap\TBC1D7-LOC100130357" "viable,fertile" FBgn0040268 Top3alpha Topoisomerase 3alpha http://flybase.org/reports/FBgn0040268 protein_coding_gene "DNA topoisomerase type I activity ; GO:0003917 | inferred from electronic annotation with InterPro:IPR000380, InterPro:IPR023406 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000380, InterPro:IPR003601, InterPro:IPR003602, InterPro:IPR013497, InterPro:IPR013498 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR010666 DNA topoisomerase activity ; GO:0003916 | inferred from direct assay" "DNA topological change ; GO:0006265 | inferred from electronic annotation with InterPro:IPR000380, InterPro:IPR003601, InterPro:IPR003602, InterPro:IPR013497, InterPro:IPR013498 mitochondrial genome maintenance ; GO:0000002 | inferred from mutant phenotype developmental growth ; GO:0048589 | inferred from mutant phenotype tissue regeneration ; GO:0042246 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype" chromosome ; GO:0005694 | inferred from electronic annotation with InterPro:IPR013498 mitochondrion ; GO:0005739 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DmTop3alpha, Top3a, dTopoIIIa, CG10123, Top3alpha, Topo IIIalpha, top3alpha, topo IIIalpha" "IPR000380:DNA topoisomerase, type IA, IPR003601:DNA topoisomerase, type IA, domain 2, IPR003602:DNA topoisomerase, type IA, DNA-binding domain, IPR006171:TOPRIM domain, IPR013497:DNA topoisomerase, type IA, central, IPR013498:DNA topoisomerase, type IA, zn finger, IPR023405:DNA topoisomerase, type IA, core domain, IPR023406:DNA topoisomerase, type IA, active site, IPR034144:DNA topoisomerase 3-like, TOPRIM domain, IPR013825:DNA topoisomerase, type IA, central region, subdomain 2, IPR010666:Zinc finger, GRF-type" CG10123 11-Aug-17 DroID_v2017_08 Drer\top3a Scer\TOP3 Cele\top-3 "Xtro\top3b, Xtro\top3a" "Mmus\Top3b, Mmus\Top3a" "Hsap\TOP3B, Hsap\TOP3A" "visible,conditional,size defective,female sterile,male sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,developmental rate defective,lethal - all die before end of prepupal stage,recessive,some die during prepupal stage,viable,lethal,melanotic necrosis" "eye,conditional,egg,maternal effect,testis,sperm individualization complex, with Top3‘±54,imaginal disc,sperm individualization complex, with Top3‘±M1L.TAvicGFP-EYFP,melanotic mass" FBgn0032362 spz4 spatzle 4 http://flybase.org/reports/FBgn0032362 protein_coding_gene Toll binding ; GO:0005121 | inferred from sequence or structural similarity with spz Toll signaling pathway ; GO:0008063 | inferred from sequence or structural similarity with spz extracellular region ; GO:0005576 | inferred from sequence or structural similarity with spz "CG14928, Spz4, spz4, CT34755" "IPR029034:Cystine-knot cytokine, IPR032104:Spaetzle" CG14928 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02410 IE 1.088307464 1.509271305 2.088802389 -1.519118626 0.195574073 0.08780924 FBgn0085756 CR40613 - http://flybase.org/reports/FBgn0085756 rRNA_gene - - - CR40613 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267939 CR46219 - http://flybase.org/reports/FBgn0267939 non_protein_coding_gene - - - "CR46219, lincRNA.903" - CR46219 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259282 C37 - http://flybase.org/reports/FBgn0259282 gene - - - C37 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin,chaeta" FBgn0063781 accord2\gag accord2 element gag http://flybase.org/reports/FBgn0063781 transposable_element_gene - - - "qbert\gag, accord2\gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005104 gusC gustatory C http://flybase.org/reports/FBgn0005104 - gene molecular_function ; GO:0003674 | no biological data available larval feeding behavior ; GO:0030536 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gusC - - 11-Aug-17 DroID_v2017_08 - - - - - - taste perception defective FBgn0266384 CR45026 - http://flybase.org/reports/FBgn0266384 non_protein_coding_gene - - - CR45026 - CR45026 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260103 2L0372 - http://flybase.org/reports/FBgn0260103 gene - "lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype" - 2L0372 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval dorsal trunk,somatic clone" FBgn0051346 CG31346 - http://flybase.org/reports/FBgn0051346 protein_coding_gene - - - CG31346 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065410 l(2)SH1570 lethal (2) SH1570 http://flybase.org/reports/FBgn0065410 gene - - - "l(2)SH1570, l(2)SH2 1570" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086170 nkd::Hsap\NKD2 - http://flybase.org/reports/FBgn0086170 engineered_fusion_gene - - - nkd::Hsap\NKD2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086210 su(comp)3L-2 - http://flybase.org/reports/FBgn0086210 gene - - - su(comp)3L-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038541 TyrRII Tyramine receptor II http://flybase.org/reports/FBgn0038541 protein_coding_gene G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity G-protein coupled amine receptor activity ; GO:0008227 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity tyramine signaling pathway ; GO:0071928 | inferred from direct assay cellular response to amine stimulus ; GO:0071418 | inferred from direct assay adenylate cyclase-activating dopamine receptor signaling pathway ; GO:0007191 | inferred from biological aspect of ancestor with PANTHER:PTN000665343 phospholipase C-activating dopamine receptor signaling pathway ; GO:0060158 | inferred from biological aspect of ancestor with PANTHER:PTN000665343 learning ; GO:0007612 | inferred from biological aspect of ancestor with PANTHER:PTN000665343 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ; GO:0007193 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "DmCG16766, anon-WO0170980.125, anon-WO0170980.124, TyrRII, CG16766" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG16766 11-Aug-17 DroID_v2017_08 "Drer\drd7, Drer\drd4b, Drer\drd6b, Drer\drd1b, Drer\LOC563567, Drer\drd2a, Drer\hrh2b, Drer\drd2l, Drer\si:dkey-247m21.3, Drer\drd3, Drer\htr4, Drer\LOC567498, Drer\drd4-rs, Drer\drd2b, Drer\drd4a, Drer\drd1a" - Cele\tyra-3 "Xtro\htr4, Xtro\drd2" "Mmus\Drd4, Mmus\Htr4, Mmus\Adra1d, Mmus\Ptger4, Mmus\Drd5, Mmus\Drd1, Mmus\Drd3, Mmus\Drd2, Mmus\Hrh2" "Hsap\DRD4, Hsap\ADRA1D, Hsap\DRD1, Hsap\HTR4, Hsap\HRH2, Hsap\PTGER4, Hsap\DRD2, Hsap\DRD5, Hsap\DRD3" FBgn0004481 l(1)air6 lethal aberrant immune response 6 http://flybase.org/reports/FBgn0004481 - gene - - - "air6, l(1)air[6], l(1)air6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,melanotic mass phenotype" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass,embryonic/larval proventriculus,foregut imaginal ring,embryonic/larval lymph gland" FBgn0034199 Gbp1 Growth-blocking peptide 1 http://flybase.org/reports/FBgn0034199 protein_coding_gene cytokine activity ; GO:0005125 | inferred from mutant phenotype response to wounding ; GO:0009611 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from genetic interaction with imd inositol phosphate metabolic process ; GO:0043647 | inferred from direct assay positive regulation of homotypic cell-cell adhesion ; GO:0034112 | inferred from direct assay cellular response to amino acid stimulus ; GO:0071230 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway ; GO:0051482 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype antimicrobial peptide production ; GO:0002775 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred by curator from GO:0005125 "Gbp, CG15917, GBP, Gbp1, gbp1" - CG15917 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,immune response defective,stress response defective,viable" FBgn0267456 CR45806 - http://flybase.org/reports/FBgn0267456 non_protein_coding_gene - - - CR45806 - CR45806 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052280 CG32280 - http://flybase.org/reports/FBgn0052280 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GM08588, CG32280" IPR006629:LPS-induced tumour necrosis factor alpha factor CG32280 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-75b4.8, Drer\si:ch211-202h22.9, Drer\cdip1, Drer\si:ch211-202h22.7, Drer\si:ch211-157c3.4, Drer\ubald1a, Drer\si:ch211-202h22.8, Drer\litaf" - "Cele\Y37D8A.6, Cele\Y87G2A.19, Cele\F36G3.3, Cele\B0348.1, Cele\C08E8.1, Cele\Y87G2A.18, Cele\Y37D8A.26, Cele\B0348.2, Cele\F16F9.1, Cele\Y37D8A.8, Cele\Y40H7A.11, Cele\Y22D7AL.15" "Xtro\cdip1, Xtro\litaf" "Mmus\Litaf, Mmus\Cdip1" "Hsap\LITAF, Hsap\CDIP1" "viable,fertile" FBgn0260023 veguero veguero http://flybase.org/reports/FBgn0260023 gene - - - veguero - - 11-Aug-17 DroID_v2017_08 - - - - - - chorion | germline clone FBgn0031377 CG15356 - http://flybase.org/reports/FBgn0031377 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR033482" nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay Sin3-type complex ; GO:0070822 | inferred from direct assay "CG15356, EMSY" "IPR005491:ENT domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR033482:BRCA2-interacting transcriptional repressor EMSY" CG15356 11-Aug-17 DroID_v2017_08 Drer\emsy - - Xtro\emsy Mmus\Emsy Hsap\EMSY FBgn0000694 flrdR flight reduced R http://flybase.org/reports/FBgn0000694 - gene - - - "flrd-R, flrdR" - - 11-Aug-17 DroID_v2017_08 - - - - - - "hypoactive,flight defective" FBgn0052252 CR32252 - http://flybase.org/reports/FBgn0052252 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32252, BcDNA:AT23419, CR32252" - CR32252 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259857 Su(Ste):CR42426 Su(Ste):CR42426 http://flybase.org/reports/FBgn0259857 non_protein_coding_gene - - - "Su(Ste):CR42426, CR42426" - CR42426 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003017 ot outheld http://flybase.org/reports/FBgn0003017 - gene - - - "l(1)19Ab, ot" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,viable,male,reduced,lethal" "wing,ocellar bristle,microchaeta,microchaeta & adult thorax" FBgn0038872 Nelf-A Negative elongation factor A http://flybase.org/reports/FBgn0038872 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:P92204 negative regulation of transcription from RNA polymerase II promoter during mitosis ; GO:0007070 | inferred from sequence or structural similarity with UniProtKB:P92204 negative regulation of transcription elongation from RNA polymerase II promoter ; GO:0034244 | inferred from direct assay NELF complex ; GO:0032021 | inferred from physical interaction with TH1 transcriptional repressor complex ; GO:0017053 | inferred from sequence or structural similarity with UniProtKB:P92204 nucleus ; GO:0005634 | inferred from direct assay "BcDNA:SD07139, CG5874, Nelf-A, NELF, NELF-A" - CG5874 11-Aug-17 DroID_v2017_08 Drer\nelfa - - Xtro\nelfa Mmus\Nelfa Hsap\NELFA "small body,lethal - all die before end of embryonic stage,germline clone,maternal effect,some die during embryonic stage,lethal" FBgn0032082 CG18088 - http://flybase.org/reports/FBgn0032082 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" - "CG18088, gi7297472, gi21430616" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG18088 11-Aug-17 DroID_v2017_08 - - "Cele\K03A11.4, Cele\F07C3.3, Cele\M03F8.5, Cele\F32G8.2, Cele\F32D8.2, Cele\T07G12.3, Cele\Y38A10A.2, Cele\T23E1.1, Cele\Y73F8A.35, Cele\R03G8.3, Cele\R03G8.1, Cele\F10C2.3, Cele\F15H10.7, Cele\Y41E3.1" - - - viable FBgn0030868 CG12986 - http://flybase.org/reports/FBgn0030868 protein_coding_gene - - - CG12986 - CG12986 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,planar polarity defective" trichogen cell FBgn0069339 UY1844 UY1844 http://flybase.org/reports/FBgn0069339 gene - - - UY1844 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell" FBgn0262991 CR43299 - http://flybase.org/reports/FBgn0262991 non_protein_coding_gene - - - CR43299 - CR43299 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021795 Tapdelta Translocon-associated protein delta http://flybase.org/reports/FBgn0021795 "FBgn0027912, FBgn0064943" protein_coding_gene signal sequence binding ; GO:0005048 | inferred from sequence or structural similarity protein retention in ER lumen ; GO:0006621 | inferred from sequence or structural similarity "endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR008855 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008855 lipid particle ; GO:0005811 | inferred from direct assay signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from sequence or structural similarity endomembrane system ; GO:0012505 | inferred from direct assay" "TRAPdelta, l(2)k17005, Tapdelta, CG9035, BcDNA:GM12291" IPR008855:Translocon-associated CG9035 11-Aug-17 DroID_v2017_08 Drer\ssr4 - Cele\trap-4 Xtro\ssr4 Mmus\Ssr4 Hsap\SSR4 "lethal,recessive,viable" embryonic/larval salivary gland FBgn0264905 CR44096 - http://flybase.org/reports/FBgn0264905 non_protein_coding_gene - - - "CR44096, lincRNA.827" - CR44096 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070013 BG01228 BG01228 http://flybase.org/reports/FBgn0070013 gene - - - BG01228 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0033820 CG4716 - http://flybase.org/reports/FBgn0033820 protein_coding_gene methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity ; GO:0004486 | non-traceable author statement - - "gh18008, BEST:GH18008, CG4716, GH16, Dmel_CG4716" - CG4716 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028078 l(3)S086405 lethal (3) S086405 http://flybase.org/reports/FBgn0028078 gene - - - "0864/05, l(3)S086405" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0013542 l(2)A1-2-12 lethal (2) A1-2-12 http://flybase.org/reports/FBgn0013542 - gene - - - l(2)A1-2-12 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053831 His1:CG33831 His1:CG33831 http://flybase.org/reports/FBgn0053831 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33831, His1:CG33831" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33831 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.10, Drer\h1f0, Drer\si:ch211-113a14.24, Drer\zgc:110425, Drer\h1fx, Drer\si:ch1073-159d7.7, Drer\zgc:110216, Drer\histh1l, Drer\si:ch73-36p18.1, Drer\zgc:153405, Drer\zgc:163061, Drer\si:dkey-108k21.14, Drer\h1m, Drer\si:dkey-108k21.21, Drer\si:dkey-261m9.12" Scer\HHO1 "Cele\hil-3, Cele\hil-6, Cele\hil-4, Cele\his-24, Cele\hil-1, Cele\hil-5, Cele\hil-2" - "Mmus\H1fnt, Mmus\Hils1, Mmus\Hist1h1e, Mmus\Hist1h1c, Mmus\H1foo, Mmus\Hist1h1d, Mmus\H1fx, Mmus\Hist1h1b, Mmus\Hist1h1t, Mmus\Hist1h1a" "Hsap\HIST1H1T, Hsap\H1FX, Hsap\H1F0, Hsap\HIST1H1A, Hsap\HIST1H1B, Hsap\H1FNT, Hsap\HIST1H1E, Hsap\HIST1H1C, Hsap\HIST1H1D, Hsap\H1FOO" FBgn0060760 l(3)S063319 lethal (3) S063319 http://flybase.org/reports/FBgn0060760 gene - - - "0633/19, l(3)S063319" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029147 NtR NtR http://flybase.org/reports/FBgn0029147 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR006201 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006201 "DNtR, CG6698, anon-WO0138359.3, NtR" "IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR022041:Farnesoic acid O-methyl transferase" CG6698 11-Aug-17 DroID_v2017_08 "Drer\chrne, Drer\chrna2a, Drer\si:ch211-39a7.1, Drer\htr3a, Drer\si:ch211-256e16.4, Drer\LOC101882451, Drer\chrna2b, Drer\chrna9, Drer\chrnb3b, Drer\chrnd, Drer\chrna6, Drer\chrna10a, Drer\chrna7, Drer\chrng, Drer\chrnb2l, Drer\chrna3, Drer\chrnb3a, Drer\chrnb1l, Drer\chrna5, Drer\chrna1, Drer\LOC798522, Drer\htr3b, Drer\chrnb4, Drer\chrna4b, Drer\chrnb1, Drer\chrnb2b" - "Cele\acr-19, Cele\acr-15, Cele\eat-2, Cele\acr-16, Cele\acr-14, Cele\W10G11.17, Cele\acr-11, Cele\acr-10, Cele\acr-7, Cele\acr-9, Cele\acr-25" "Xtro\chrnb3, Xtro\chrna1, Xtro\chrnd, Xtro\chrng, Xtro\chrna2, Xtro\chrna9, Xtro\chrna1.2, Xtro\chrna5, Xtro\chrna7, Xtro\chrne, Xtro\chrnb2, Xtro\chrna6" "Mmus\Chrnb1, Mmus\Chrna9, Mmus\Htr3a, Mmus\Chrng, Mmus\Chrna2, Mmus\Chrnd, Mmus\Chrnb3, Mmus\Chrnb4, Mmus\Chrna7, Mmus\Htr3b, Mmus\Chrna5, Mmus\Chrna3, Mmus\Chrna10, Mmus\Chrna6, Mmus\Chrne, Mmus\Chrna1, Mmus\Chrna4, Mmus\Chrnb2" "Hsap\CHRNA6, Hsap\CHRNB2, Hsap\CHRNA7, Hsap\CHRNA5, Hsap\CHRNB3, Hsap\HTR3E, Hsap\HTR3C, Hsap\CHRNA9, Hsap\HTR3B, Hsap\CHRNA4, Hsap\CHRNA2, Hsap\CHRNA3, Hsap\CHRNB1, Hsap\HTR3A, Hsap\CHRNA1, Hsap\HTR3D, Hsap\CHRNA10, Hsap\CHRFAM7A, Hsap\CHRND, Hsap\CHRNG, Hsap\CHRNB4, Hsap\CHRNE" viable FBgn0265455 CG44355 - http://flybase.org/reports/FBgn0265455 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44355 - CG44355 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083268 E(smoDN)391 Enhancer of smoDN 391 http://flybase.org/reports/FBgn0083268 gene - - - E(smoDN)391 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037845 CG14694 - http://flybase.org/reports/FBgn0037845 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000841430 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000841430 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002666 CG14694 "IPR002666:Reduced folate carrier, IPR020846:Major facilitator superfamily domain" CG14694 11-Aug-17 DroID_v2017_08 "Drer\slc19a1, Drer\slc19a3b, Drer\slc19a2, Drer\slc19a3a" - "Cele\folt-2, Cele\folt-3, Cele\folt-1" "Xtro\slc19a1, Xtro\slc19a2" "Mmus\Slc19a2, Mmus\Slc19a3, Mmus\Slc19a1" "Hsap\SLC19A3, Hsap\C2orf83, Hsap\SLC19A2, Hsap\SLC19A1" viable FBgn0065308 l(2)SH1963 lethal (2) SH1963 http://flybase.org/reports/FBgn0065308 gene - - - "l(2)SH1963, l(2)SH2 1963" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038233 HtrA2 HTRA2-related serine protease http://flybase.org/reports/FBgn0038233 protein_coding_gene peptidase activity ; GO:0008233 | inferred from direct assay serine-type endopeptidase activity ; GO:0004252 | inferred from mutant phenotype serine-type endopeptidase activity ; GO:0004252 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24306 protein binding ; GO:0005515 | inferred from physical interaction with rho-7 regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity ; GO:2001056 | inferred from direct assay mitochondrion organization ; GO:0007005 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype mitochondrial intermembrane space ; GO:0005758 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay Nebenkern ; GO:0016006 | inferred from direct assay "CG8464, HtrA2, DmHtrA2, HtrA2/Omi, Omi, dOmi, domi, htrA2, omi, htrA2/omi" "IPR001478:PDZ domain, IPR001940:Peptidase S1C, IPR009003:Peptidase S1, PA clan" CG8464 11-Aug-17 DroID_v2017_08 "Drer\LOC797799, Drer\zgc:174193, Drer\LOC560917, Drer\LOC100003308, Drer\si:dkey-33c12.2, Drer\si:busm1-sl7.7, Drer\LOC799006, Drer\htra3a, Drer\LOC100000024, Drer\si:dkey-84o3.2, Drer\LOC793110, Drer\LOC100331049, Drer\si:dkey-19p15.4, Drer\si:dkey-84o3.7, Drer\si:dkey-112g5.16, Drer\htra1a, Drer\htra4, Drer\LOC793521, Drer\nagk, Drer\zgc:173425, Drer\htra1b, Drer\LOC100149563, Drer\htra3b, Drer\si:dkey-33c12.10, Drer\si:dkey-84o3.3" Scer\NMA111 Cele\C52A11.3 "Xtro\htra1, Xtro\tysnd1, Xtro\htra4, Xtro\nagk" "Mmus\Htra4, Mmus\Htra3, Mmus\Tysnd1, Mmus\Nagk, Mmus\Htra2, Mmus\Htra1" "Hsap\HTRA1, Hsap\NAGK, Hsap\HTRA2, Hsap\HTRA3, Hsap\HTRA4, Hsap\TYSND1" "viable,fertile,radiation resistant,chemical resistant,visible,heat sensitive,male sterile,partially lethal - majority die,male fertile,decreased cell death,female fertile,dominant,flightless,locomotor behavior defective,short lived,chemical sensitive" "eye | pupal stage,eye,heat sensitive,indirect flight muscle,spermatid cyst,investment coneED5644),male germline cell,spermatogonial cyst,mitochondrion & indirect flight muscle,spermatozoon" FBgn0005116 l(1)ff lethal (1) formalin food http://flybase.org/reports/FBgn0005116 - gene - - - "Lff11, l(1)ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval pharynx,embryonic brain,embryonic segment,embryonic/first instar larval cuticle,dorsal" FBgn0067911 GS(2)A096 GS(2)A096 http://flybase.org/reports/FBgn0067911 gene - - - GS(2)A096 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "ventral nerve cord commissure,longitudinal connective,RP1 motor neuron,lateral longitudinal fascicle" FBgn0036161 CG7551 - http://flybase.org/reports/FBgn0036161 protein_coding_gene ketohexokinase activity ; GO:0004454 | inferred from sequence or structural similarity with HGNC:6315 fructokinase activity ; GO:0008865 | inferred from sequence or structural similarity with HGNC:6315 fructose metabolic process ; GO:0006000 | inferred from electronic annotation with InterPro:IPR034093 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:6315 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6315 "BcDNA:AT07524, CG7551" "IPR011611:Carbohydrate kinase PfkB, IPR034093:Ketohexokinase, IPR029056:Ribokinase-like" CG7551 11-Aug-17 DroID_v2017_08 Drer\khk - "Cele\R07H5.8, Cele\grl-29, Cele\grl-5, Cele\grl-18, Cele\grl-26, Cele\grl-31, Cele\grl-27, Cele\grl-30, Cele\grl-3, Cele\grl-28, Cele\grl-21, Cele\grl-15, Cele\grl-20, Cele\grl-6" Xtro\khk Mmus\Khk Hsap\KHK FBgn0040544 CG14700 - http://flybase.org/reports/FBgn0040544 protein_coding_gene - - - CG14700 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050223 tRNA:His-GTG-1-5 transfer RNA:Histidine-GTG 1-5 http://flybase.org/reports/FBgn0050223 tRNA_gene CAC codon-amino acid adaptor activity ; GO:0033426 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033426 cytosol ; GO:0005829 | inferred by curator from GO:0033426 "AE002787.trna9-HisGTG, tRNA:H:GTG:AE002787-a, tRNA:CR30223, CR30223, tRNA:his:56E, tRNA[His], chr2R.trna67-HisGTG, tRNA-His-GTG-1-5, tRNA:His-GTG-1-5, tRNA:H:56E, CAC" - CR30223 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039058 VhaAC39-2 Vacuolar H[+] ATPase AC39 subunit 2 http://flybase.org/reports/FBgn0039058 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000004439" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR016727 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033176,GO:0046961 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" "proton-transporting V-type ATPase, V0 domain ; GO:0033179 | inferred from electronic annotation with InterPro:IPR016727 proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity withFB:FBgn0028665" "anon-WO0118547.227, VhaAC39-2, vhaAC39-2, CG4624, V0d" "IPR002843:ATPase, V0 complex, c/d subunit, IPR016727:ATPase, V0 complex, subunit d" CG4624 11-Aug-17 DroID_v2017_08 Drer\atp6v0d1 Scer\VMA6 Cele\vha-16 "Xtro\atp6v0d2, Xtro\atp6v0d1" "Mmus\Atp6v0d2, Mmus\Atp6v0d1" "Hsap\ATP6V0D1, Hsap\ATP6V0D2" viable FBgn0015789 Rab10 Rab10 http://flybase.org/reports/FBgn0015789 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype vesicle docking involved in exocytosis ; GO:0006904 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 cellular response to insulin stimulus ; GO:0032869 | inferred from biological aspect of ancestor with PANTHER:PTN000756399 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 lateral inhibition ; GO:0046331 | inferred from mutant phenotype basal protein localization ; GO:0045175 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000756399 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 cell trailing edge ; GO:0031254 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay insulin-responsive compartment ; GO:0032593 | inferred from biological aspect of ancestor with PANTHER:PTN000756399 neuronal cell body ; GO:0043025 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay "AAF50924, DmRab10, rab10, CG17060, DRab10, DRAB10, Rab-r10, Rab10, O15971" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17060 11-Aug-17 DroID_v2017_08 "Drer\zgc:162879, Drer\rab44, Drer\LOC100535415, Drer\rab40c, Drer\rab40b, Drer\rab1aa, Drer\rab8b, Drer\rab8a, Drer\rab1ab, Drer\rab12, Drer\rasef, Drer\rab13, Drer\rab35b, Drer\rab15, Drer\zgc:171927, Drer\rab10, Drer\si:dkey-16l2.16" Scer\SEC4 "Cele\K02E10.1, Cele\rab-8, Cele\rab-10, Cele\rab-1, Cele\rab-35" "Xtro\rab44, Xtro\rasef, Xtro\LOC100135070, Xtro\rab13, Xtro\rab8b, Xtro\rab15, Xtro\rab1a, Xtro\rasef, Xtro\rab28, Xtro\rab35, Xtro\rab12, Xtro\rab10, Xtro\rab40b, Xtro\rab8a, Xtro\rab35" "Mmus\Rab40b, Mmus\Rab8a, Mmus\Rab13, Mmus\Rab8b, Mmus\Rab12, Mmus\Rab28, Mmus\Rab44, Mmus\Rab15, Mmus\Rab35, Mmus\Rab40c, Mmus\Rab1b, Mmus\Rasef, Mmus\Rab1a, Mmus\Rab10" "Hsap\RAB35, Hsap\RAB40A, Hsap\RAB15, Hsap\RAB12, Hsap\RAB40C, Hsap\RAB8B, Hsap\RAB40B, Hsap\RASEF, Hsap\RAB40AL, Hsap\RAB1B, Hsap\RAB1A, Hsap\RAB8A, Hsap\RAB13, Hsap\RAB28, Hsap\RAB10" "visible,body color defective,partially lethal - majority die,some die during pupal stage,viable" "chaeta,supernumerary,mesothoracic tergum,egg" FBgn0065843 l(2)SH0321 lethal (2) SH0321 http://flybase.org/reports/FBgn0065843 gene - - - "l(2)SH0321, l(2)SH2 0321" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040780 Atg10 Autophagy-related 10 http://flybase.org/reports/FBgn0040780 protein_coding_gene Atg12 transferase activity ; GO:0019777 | inferred from sequence or structural similarity with SGD:S000003965 macroautophagy ; GO:0016236 | inferred from sequence or structural similarity with SGD:S000003965 cellular protein modification process ; GO:0006464 | inferred from sequence or structural similarity with SGD:S000003965 cellular_component ; GO:0005575 | no biological data available "CG12821, Atg10, ATG10" IPR007135:Autophagy-related protein 3 CG12821 11-Aug-17 DroID_v2017_08 Drer\atg10 - "Cele\atg-10, Cele\D2085.7, Cele\atg-3" - Mmus\Atg10 Hsap\ATG10 FBgn0027957 l(3)S148011a lethal (3) S148011a http://flybase.org/reports/FBgn0027957 gene - - - "1480/11, l(3)S148011, l(3)S148011a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0265049 CR44164 - http://flybase.org/reports/FBgn0265049 non_protein_coding_gene - - - CR44164 - CR44164 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000538 eb extra bristles http://flybase.org/reports/FBgn0000538 - gene - - - eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "macrochaeta & scutum,scutellar bristle" FBgn0283460 mir-10404 mir-10404 stem loop http://flybase.org/reports/FBgn0283460 miRNA_gene - gene silencing by miRNA ; GO:0035195 | inferred from direct assay - "mir-10404, mir-10404/mir-ITS1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262623 CG43147 - http://flybase.org/reports/FBgn0262623 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43147, lincRNA.541" - CG43147 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050213 CR30213 - http://flybase.org/reports/FBgn0050213 non_protein_coding_gene - - - "CR30139, CR30136, CR30213" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262293 mir-2490 mir-2490 stem loop http://flybase.org/reports/FBgn0262293 miRNA_gene - - - "mir-2490, CR43000, dme-mir-2490" - CR43000 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040832 CG8012 - http://flybase.org/reports/FBgn0040832 protein_coding_gene - - - "BcDNA:GH26995, CG8012" - CG8012 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002304 l(3)84Cb lethal (3) 84Cb http://flybase.org/reports/FBgn0002304 - gene - - - l(3)84Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027962 l(3)S145710a lethal (3) S145710a http://flybase.org/reports/FBgn0027962 gene - - - "1067/10, 0479/06, l(3)S106710a, l(3)S145710, l(3)S145710a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038641 CG7708 - http://flybase.org/reports/FBgn0038641 protein_coding_gene choline transmembrane transporter activity ; GO:0015220 | inferred from sequence or structural similarity with UniProtKB:Q9GZV3 choline binding ; GO:0033265 | inferred from biological aspect of ancestor with PANTHER:PTN001721680 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 choline:sodium symporter activity ; GO:0005307 | inferred from biological aspect of ancestor with PANTHER:PTN001721680 acetylcholine biosynthetic process ; GO:0008292 | inferred from sequence or structural similarity with UniProtKB:Q9GZV3 choline transport ; GO:0015871 | inferred from biological aspect of ancestor with PANTHER:PTN001721680 acetylcholine biosynthetic process ; GO:0008292 | inferred from biological aspect of ancestor with PANTHER:PTN001721680 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9GZV3 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000213391 "CG7708, dSLC5A15" IPR001734:Sodium/solute symporter CG7708 11-Aug-17 DroID_v2017_08 "Drer\LOC799259, Drer\slc5a7a" Scer\DUR3 Cele\cho-1 Xtro\slc5a7 Mmus\Slc5a7 Hsap\SLC5A7 viable FBgn0030003 CG2116 - http://flybase.org/reports/FBgn0030003 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - CG2116 IPR013087:Zinc finger C2H2-type CG2116 11-Aug-17 DroID_v2017_08 "Drer\znf668, Drer\zgc:162948, Drer\znf142, Drer\im:7147486" Scer\RME1 "Cele\fezf-1, Cele\M03D4.4, Cele\sdz-12, Cele\eor-1, Cele\hinf-1" Xtro\znf668 "Mmus\Zfp574, Mmus\Zfp142, Mmus\Zfp668" "Hsap\ZNF215, Hsap\ZIK1, Hsap\ZNF212, Hsap\ZNF713, Hsap\ZNF75A, Hsap\ZNF746, Hsap\ZNF398, Hsap\ZNF777, Hsap\ZNF574, Hsap\ZNF705E, Hsap\ZNF587B, Hsap\ZNF705B, Hsap\ZNF705D, Hsap\ZNF763, Hsap\ZNF705G, Hsap\ZNF282, Hsap\ZNF668, Hsap\ZNF705A, Hsap\ZNF142, Hsap\ZNF552" "neuroanatomy defective,viable" "dorsal multidendritic neuron ddaC,ventral multidendritic neuron vdaB,abdominal ventral multidendritic neuron v'dap" FBgn0011284 RpS4 Ribosomal protein S4 http://flybase.org/reports/FBgn0011284 FBgn0025296 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002942 structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000876 centrosome organization ; GO:0051297 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "SX4, rpS4, RPS4, anon-EST:Posey270, CG11276, RpS4, Rp S4" "IPR018199:Ribosomal protein S4e, N-terminal, conserved site, IPR000876:Ribosomal protein S4e, IPR002942:RNA-binding S4 domain, IPR005824:KOW, IPR013843:Ribosomal protein S4e, N-terminal, IPR013845:Ribosomal protein S4e, central region, IPR032277:40S ribosomal protein S4, C-terminal domain" CG11276 11-Aug-17 DroID_v2017_08 Drer\rps4x "Scer\RPS4A, Scer\RPS4B" Cele\rps-4 Xtro\rps4x Mmus\Rps4x "Hsap\RPS4Y2, Hsap\RPS4X, Hsap\RPS4Y1" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC11272 EK -0.82511944 -0.274034651 0.15711297 -3.774973909 1.255007503 3.195982836 FBgn0001493 l(1)10Bg lethal (1) 10Bg http://flybase.org/reports/FBgn0001493 - gene - - - "10Bg, l(1)GLM20, l(1)G20, l(1)10Bg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect,lethal" "ovariole,germline clone,egg,egg chamber,maternal effect,macrochaeta" FBgn0014930 CG2846 - http://flybase.org/reports/FBgn0014930 - protein_coding_gene riboflavin kinase activity ; GO:0008531 | inferred from sequence or structural similarity with SGD:S000002644 "riboflavin biosynthetic process ; GO:0009231 | inferred from electronic annotation with InterPro:IPR015865, InterPro:IPR023465 FMN biosynthetic process ; GO:0009398 | inferred from sequence or structural similarity with SGD:S000002644" cellular_component ; GO:0005575 | no biological data available "C, anon-84Ea, CG2846" "IPR023465:Riboflavin kinase domain, IPR023468:Riboflavin kinase, IPR015865:Riboflavin kinase domain, bacterial/eukaryotic" CG2846 11-Aug-17 DroID_v2017_08 Drer\rfk Scer\FMN1 Cele\R10H10.6 Xtro\rfk Mmus\Rfk Hsap\RFK DRSC15454 I 1.514014056 0.622911737 0.207042151 0.017693266 0.653123358 -0.238126751 FBgn0034071 CG8405 - http://flybase.org/reports/FBgn0034071 protein_coding_gene - "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - "CG8405, R5_2R:11947059..11948303" IPR019144:Membralin CG8405 11-Aug-17 DroID_v2017_08 Drer\tmem259 - Cele\Y59C2A.2 Xtro\tmem259 Mmus\Tmem259 Hsap\TMEM259 viable FBgn0265675 CR44482 - http://flybase.org/reports/FBgn0265675 non_protein_coding_gene - - - CR44482 - CR44482 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266830 CR45292 - http://flybase.org/reports/FBgn0266830 non_protein_coding_gene - - - CR45292 - CR45292 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002128 l(2)K201 lethal (2) K201 http://flybase.org/reports/FBgn0002128 - gene - - - l(2)K201 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060469 l(3)S112803 lethal (3) S112803 http://flybase.org/reports/FBgn0060469 gene - - - "1128/03, l(3)S112803" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0261635 CG42718 - http://flybase.org/reports/FBgn0261635 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42718 - CG42718 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050332 CG30332 - http://flybase.org/reports/FBgn0050332 protein_coding_gene - - - "BcDNA:AT17896, CG30332" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016636 E(gl)3D Enhancer of glass 3D http://flybase.org/reports/FBgn0016636 - gene - - - E(gl)3D - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" presumptive embryonic/larval central nervous system FBgn0264701 CR43970 - http://flybase.org/reports/FBgn0264701 non_protein_coding_gene - - - CR43970 - CR43970 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061472 3R-I256 3R-I256 http://flybase.org/reports/FBgn0061472 gene - - - 3R-I256 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuron,somatic clone" FBgn0030109 CG12121 - http://flybase.org/reports/FBgn0030109 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009637 CG12121 IPR009637:Lung seven transmembrane receptor-like CG12121 11-Aug-17 DroID_v2017_08 "Drer\gpr107, Drer\LOC556363" - Cele\C15H9.5 Xtro\gpr107 "Mmus\Gpr107, Mmus\Gpr108" "Hsap\GPR107, Hsap\GPR108" FBgn0260576 MENE-WW14 - http://flybase.org/reports/FBgn0260576 gene - - - MENE-WW14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye disc,somatic clone" FBgn0032101 CG9586 - http://flybase.org/reports/FBgn0032101 protein_coding_gene - - - CG9586 - CG9586 11-Aug-17 DroID_v2017_08 Drer\ccdc43 - - Xtro\ccdc43 Mmus\Ccdc43 Hsap\CCDC43 viable FBgn0054005 CG34005 - http://flybase.org/reports/FBgn0054005 protein_coding_gene - - - "BP1019, CG34005" IPR007931:Protein of unknown function DUF725 CG34005 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261846 CG42778 - http://flybase.org/reports/FBgn0261846 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42778, lincRNA.767" - CG42778 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040375 CG13760 - http://flybase.org/reports/FBgn0040375 protein_coding_gene - - - "EG:BACR25B3.6, CG13760" IPR018616:Guanylyl cyclase CG13760 11-Aug-17 DroID_v2017_08 Drer\gucd1 - - Xtro\gucd1 Mmus\Gucd1 Hsap\GUCD1 "viable,visible" mesothoracic tergum FBgn0010217 ATPsynbeta "ATP synthase, beta subunit" http://flybase.org/reports/FBgn0010217 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000003882 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000003882" regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000003882 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P06576 "lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P06576" "ATP-syn-B, ATP, ATPsyn-b, CG11154, ATPsyn b, beta-ATPase, ATPB, ATPsyn-beta, ATPase beta, ATP-synbeta, ATPsyn-&bgr, ATPasebeta, ATP syn-beta, Comp V beta, ATPsynbeta, ATPase-beta, ATP-B, ATP-syn-beta" "IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR003593:AAA+ ATPase domain, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005722:ATP synthase, F1 complex, beta subunit, IPR024034:ATPase, F1/V1 complex, beta/alpha subunit, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site" CG11154 11-Aug-17 DroID_v2017_08 "Drer\zgc:163069, Drer\atp5b" "Scer\ATP4, Scer\ATP2" "Cele\asb-2, Cele\atp-2, Cele\asb-1" Xtro\atp5b "Mmus\Atp5b, Mmus\Atp5f1" "Hsap\ATP5B, Hsap\ATP5F1" "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,viable,female sterile,RU486 conditional,short lived,female,visible,partially lethal - majority die" "wing,adult thorax,chaeta" DRSC17194 K -0.919309664 0.132514835 -0.378673279 -0.049979443 1.08050153 2.743133277 FBgn0014941 anon-98Db anon-98Db http://flybase.org/reports/FBgn0014941 - gene - - - anon-98Db - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069325 X-156-10 X-156-10 http://flybase.org/reports/FBgn0069325 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-156-10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0032934 CG8679 - http://flybase.org/reports/FBgn0032934 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG8679, dLEM3" "IPR002110:Ankyrin repeat, IPR003887:LEM domain, IPR011015:LEM/LEM-like domain, IPR020683:Ankyrin repeat-containing domain" CG8679 11-Aug-17 DroID_v2017_08 "Drer\zgc:85936, Drer\si:ch211-272n13.3" - "Cele\F44E5.15, Cele\lem-3, Cele\K07D4.2" Xtro\ankle1 "Mmus\Ankrd26, Mmus\Ankrd36, Mmus\4932414N04Rik, Mmus\Ankle1, Mmus\Ankrd7, Mmus\Ccdc144b, Mmus\4921524L21Rik" "Hsap\ANKLE1, Hsap\ANKRD62, Hsap\ANKRD20A4, Hsap\ANKRD20A1, Hsap\ANKRD30A, Hsap\ANKRD20A3, Hsap\ANKRD18B, Hsap\ANKRD26, Hsap\ANKRD20A2, Hsap\ANKRD18A, Hsap\ANKRD30B" viable FBgn0085578 CG41252 - http://flybase.org/reports/FBgn0085578 protein_coding_gene - - - CG41252 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001848 l(1)ts4975 lethal (1) ts4975 http://flybase.org/reports/FBgn0001848 - gene - - - l(1)ts4975 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0016815 l(1)L18 lethal (1) L18 http://flybase.org/reports/FBgn0016815 - gene - - - "l(1)L18, L18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033973 HPS1 Hermansky-Pudlak Syndrome 1 http://flybase.org/reports/FBgn0033973 protein_coding_gene molecular_function ; GO:0003674 | no biological data available phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype BLOC-3 complex ; GO:0031085 | inferred from sequence or structural similarity with HGNC:5163 BLOC-3 complex ; GO:0031085 | inferred from direct assay "CG12855, HPS1, dHPS1, HPS, NP_610997" IPR026053:Hermansky-Pudlak syndrome 1 protein CG12855 11-Aug-17 DroID_v2017_08 Drer\hps1 - "Cele\K04F1.9, Cele\E02H9.9, Cele\Y18H1A.8" - Mmus\Hps1 Hsap\HPS1 viable FBgn0032489 CG15480 - http://flybase.org/reports/FBgn0032489 protein_coding_gene - - - CG15480 - CG15480 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum DRSC02490 K -0.236220433 0.176035602 0.442982596 0.092155641 -0.699332014 -1.574464581 FBgn0025583 IM2 Immune induced molecule 2 http://flybase.org/reports/FBgn0025583 "FBgn0034332, FBgn0044675, FBgn0047046" protein_coding_gene - defense response ; GO:0006952 | non-traceable author statement response to bacterium ; GO:0009617 | inferred from expression pattern defense response ; GO:0006952 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "DIM2, Im2, CG18106, BcDNA:RH08291, anon-WO0140519.2, IM2, DIM-2, DIM 2" IPR013172:Immune-induced protein Dim CG18106 11-Aug-17 DroID_v2017_08 - - - - - - adult stage viable FBgn0034473 Or56a Odorant receptor 56a http://flybase.org/reports/FBgn0034473 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "56a, DOR59, CG12501, 56E.1, Or56a" "IPR004117:Olfactory receptor, insect" CG12501 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267241 CR45681 - http://flybase.org/reports/FBgn0267241 non_protein_coding_gene - - - CR45681 - CR45681 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262430 mir-9c mir-9c stem loop http://flybase.org/reports/FBgn0262430 miRNA_gene - germ cell development ; GO:0007281 | inferred from mutant phenotype - "miR-9c, mir-9c, dme-mir-9c, 9c, MIR-9, CR42985, CR33564, miR-9, mir-9C, mir-9, MiR-9c, dme-miR-9c-5p, dme-miR-9c" - CR42985 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage "lethal,visible" "eye,wing,wing margin,wing margin bristle,germline cell,maternal effect" FBgn0024499 Acprep1 Accessory gland protein rep1 http://flybase.org/reports/FBgn0024499 - gene - - - "Acp rep1, Acprep1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259458 EP-654a - http://flybase.org/reports/FBgn0259458 gene - - - EP-654a - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0030598 CG9503 - http://flybase.org/reports/FBgn0030598 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG9503, Dm GMCalpha1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9503 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH FBgn0008647 S63 S63 http://flybase.org/reports/FBgn0008647 - gene - - - "S 63, S63" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044099 E(rst)C6 E(rst)C6 http://flybase.org/reports/FBgn0044099 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C6, E(rst)C6" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0025920 l(3)78Ae lethal (3) 78Ae http://flybase.org/reports/FBgn0025920 - gene - - - l(3)78Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002786 mot-36e mottled 36e http://flybase.org/reports/FBgn0002786 - gene - - - mot-36e - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,visible,eye color defective" "pigment cell,wing,wing vein,posterior crossvein,macrochaeta,microchaeta" FBgn0039735 Nph Nucleophosmin http://flybase.org/reports/FBgn0039735 protein_coding_gene histone binding ; GO:0042393 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay sperm chromatin decondensation ; GO:0035041 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG7911, Nph" "IPR004301:Nucleoplasmin family, IPR024057:Nucleoplasmin core domain" CG7911 11-Aug-17 DroID_v2017_08 "Drer\npm2a, Drer\npm2b, Drer\npm1a, Drer\npm1b" - - "Xtro\npm1, Xtro\npm2, Xtro\npm3" "Mmus\Npm2, Mmus\Npm1, Mmus\Npm3" "Hsap\NPM3, Hsap\NPM2, Hsap\NPM1" FBgn0000092 CG2650 - http://flybase.org/reports/FBgn0000092 - protein_coding_gene - circadian rhythm ; GO:0007623 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "anon-3B1.2, EG:155E2.1, 0.9, 0.9 gene, CG2650" IPR010562:Haemolymph juvenile hormone binding CG2650 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , pupal stage " " epidermis

, epidermis

{ 0 per* } " viable FBgn0014350 ms(2)HB40 ms(2)HB40 http://flybase.org/reports/FBgn0014350 - gene - - - ms(2)HB40 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041737 l(3)63Ef lethal (3) 63Ef http://flybase.org/reports/FBgn0041737 gene - - - "group I, l(3)63Ef" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036819 Dysb Dysbindin http://flybase.org/reports/FBgn0036819 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Snapin inferred from physical interaction with Blos4 "regulation of synaptic plasticity ; GO:0048167 | inferred from mutant phenotype mating behavior, sex discrimination ; GO:0048047 | inferred from mutant phenotype regulation of synapse organization ; GO:0050807 | inferred from genetic interaction with Blos1 olfactory learning ; GO:0008355 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype positive regulation of synaptic transmission, glutamatergic ; GO:0051968 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype negative regulation of dopamine metabolic process ; GO:0045963 | inferred from direct assay inferred from genetic interaction with e regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from mutant phenotype" neuromuscular junction of somatic muscle ; GO:0098527 | inferred from direct assay BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:17328 synaptic vesicle ; GO:0008021 | inferred from direct assay "Dysb, dysb, CG6856, Ddysb, NP_649064" IPR007531:Dysbindin CG6856 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-174d20.1, Drer\dtnbp1a, Drer\dtnbp1b, Drer\si:ch211-253b8.5" - Cele\dsbn-1 "Xtro\dbndd1, Xtro\dtnbp1" "Mmus\Dbndd2, Mmus\Dtnbp1, Mmus\Dbndd1" "Hsap\DBNDD2, Hsap\DBNDD1, Hsap\DTNBP1" "neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,courtship behavior defective,eye color defective,viable,visible,memory defective,recessive,locomotor behavior defective" "embryonic/larval neuromuscular junction | larval stage,trichogen cell,embryonic/larval neuromuscular junction" FBgn0053543 CG33543 - http://flybase.org/reports/FBgn0053543 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - "CG15355, CG15354, CT35364, CT35363, CG33543, 33543" "IPR003598:Immunoglobulin subtype 2, IPR003961:Fibronectin type III, IPR013098:Immunoglobulin I-set, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype, IPR013151:Immunoglobulin" CG33543 11-Aug-17 DroID_v2017_08 "Drer\opcml, Drer\ntm, Drer\zgc:110372, Drer\cep41" - - "Xtro\icam5, Xtro\negr1, Xtro\ntm, Xtro\lsamp" "Mmus\Cep41, Mmus\Opcml, Mmus\Lsamp, Mmus\Speg, Mmus\Iglon5, Mmus\Ntm" "Hsap\OPCML, Hsap\CEP41, Hsap\LSAMP, Hsap\NTM, Hsap\IGLON5" viable FBgn0039551 Or98a Odorant receptor 98a http://flybase.org/reports/FBgn0039551 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from direct assay "98a, CG5540, DOR110, 98B.1, Or98a, Or98A, DmOr98a" "IPR004117:Olfactory receptor, insect" CG5540 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038268 CG3631 - http://flybase.org/reports/FBgn0038268 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with fj protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with fj endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay CG3631 "IPR009581:FAM20, C-terminal, IPR024869:FAM20" CG3631 11-Aug-17 DroID_v2017_08 "Drer\fam20cb, Drer\fam20b, Drer\samd7, Drer\fam20a, Drer\fam20cl, Drer\fam20ca" - Cele\H03A11.1 "Xtro\samd7, Xtro\fam20a, Xtro\fam20c, Xtro\fam20b" "Mmus\Fam20c, Mmus\Fam20a, Mmus\Samd7, Mmus\Fam20b" "Hsap\FAM20B, Hsap\SAMD7, Hsap\FAM20A, Hsap\FAM20C" "viable,fertile" FBgn0053017 CG33017 - http://flybase.org/reports/FBgn0053017 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15703, CG15702, CG33017" IPR006578:MADF domain CG33017 11-Aug-17 DroID_v2017_08 - - - - Mmus\Gpatch8 Hsap\GPATCH8 viable FBgn0003641 su(w[h]) suppressor of white-honey http://flybase.org/reports/FBgn0003641 - gene - - - su(w[h]) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028156 l(3)S042228 lethal (3) S042228 http://flybase.org/reports/FBgn0028156 gene - - - "0422/28, l(3)S042228" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265177 CG44242 - http://flybase.org/reports/FBgn0265177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44242, CG8446" "IPR020373:Ribosomal protein S36, mitochondrial" CG44242 11-Aug-17 DroID_v2017_08 - Scer\AIM22 Cele\gip-2 - Mmus\Lipt1 Hsap\LIPT1 "viable,fertile" FBgn0005165 l(2)G559 lethal (2) G559 http://flybase.org/reports/FBgn0005165 - gene - - - l(2)G559 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0050211 tRNA:Trp-CCA-1-2 transfer RNA:Tryptophan-CCA 1-2 http://flybase.org/reports/FBgn0050211 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "AE002787.trna1-TrpCCA, tRNA:W:CCA:AE002787-a, CR30146, CR30211, chr2R.trna59-TrpCCA, tRNA-Trp-CCA-1-2, tRNA:Trp-CCA-1-2, tRNA:CR30211, UGG" - CR30211 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266142 CR44848 - http://flybase.org/reports/FBgn0266142 non_protein_coding_gene - - - CR44848 - CR44848 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025121 su(RpII140[Z36])S7 su(RpII140[Z36])S7 http://flybase.org/reports/FBgn0025121 - gene - - - "Z36[S7], su(RpII140[Z36])S7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030904 upd2 unpaired 2 http://flybase.org/reports/FBgn0030904 protein_coding_gene cytokine activity ; GO:0005125 | inferred from direct assay embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from electronic annotation with InterPro:IPR031901 intestinal epithelial structure maintenance ; GO:0060729 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from direct assay inferred from genetic interaction with hop inferred from genetic interaction with Stat92E inferred from genetic interaction with Socs36E inferred from genetic interaction with dome inferred from genetic interaction with Ptp61F segment specification ; GO:0007379 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype paracrine signaling ; GO:0038001 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "Upd2, upd2, CG5988, cg5988, UPD2, Upd2/Leptin, Upd-like, upd, unpaired 2" IPR031901:Unpaired protein CG5988 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,immune response defective,recessive,small body,decreased cell number,decreased cell size" "wing,embryonic/larval oenocyte" FBgn0266118 suffix\ORF - http://flybase.org/reports/FBgn0266118 transposable_element_gene - - - suffix\ORF - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027084 LysRS Lysyl-tRNA synthetase http://flybase.org/reports/FBgn0027084 FBgn0030143 protein_coding_gene "lysine-tRNA ligase activity ; GO:0004824 | inferred from electronic annotation with InterPro:IPR002313, InterPro:IPR018149 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002313, InterPro:IPR004364, InterPro:IPR018149, InterPro:IPR018150 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004365 lysine-tRNA ligase activity ; GO:0004824 | traceable author statement" "lysyl-tRNA aminoacylation ; GO:0006430 | inferred from electronic annotation with InterPro:IPR002313, InterPro:IPR018149 lysyl-tRNA aminoacylation ; GO:0006430 | traceable author statement" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR018149 cytoplasm ; GO:0005737 | traceable author statement aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay mitochondrion ; GO:0005739 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay "LysRS, KRS, CG12141, Aats-lys" "IPR002313:Lysine-tRNA ligase, class II, IPR004364:Aminoacyl-tRNA synthetase, class II (D/K/N), IPR004365:OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR012340:Nucleic acid-binding, OB-fold, IPR018149:Lysyl-tRNA synthetase, class II, C-terminal, IPR034762:Bacterial/eukaryotic lysine-tRNA ligase, class II" CG12141 11-Aug-17 DroID_v2017_08 Drer\kars "Scer\KRS1, Scer\MSK1" Cele\kars-1 Xtro\kars Mmus\Kars Hsap\KARS embryonic stage "

ubiquitous , embryonic/larval salivary gland

" FBgn0266625 CR45132 - http://flybase.org/reports/FBgn0266625 non_protein_coding_gene - - - CR45132 - CR45132 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061103 l(3)S008702 lethal (3) S008702 http://flybase.org/reports/FBgn0061103 gene - - - "1004/09, 0947/13, 0737/04, 0680/02, 0087/02, l(3)S073704b, l(3)S094713, l(3)S100409b, l(3)S068002b, l(3)S008702b, l(3)S008702" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0083298 E(smoDN)1835 Enhancer of smoDN 1835 http://flybase.org/reports/FBgn0083298 gene - - - E(smoDN)1835 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001261 inaB inactivation no afterpotential B http://flybase.org/reports/FBgn0001261 - gene - - - inaB - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,visual behavior defective" "photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6" FBgn0014194 hyl hyl http://flybase.org/reports/FBgn0014194 - gene - - - hyl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085702 CG41576 - http://flybase.org/reports/FBgn0085702 protein_coding_gene - - - CG41576 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050418 nord nord http://flybase.org/reports/FBgn0050418 protein_coding_gene molecular_function ; GO:0003674 | no biological data available olfactory learning ; GO:0008355 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG3372, CG13574, CG30418, nord, E3272" "IPR003961:Fibronectin type III, IPR019326:Protein of unknown function DUF2369, IPR013783:Immunoglobulin-like fold" CG30418 11-Aug-17 DroID_v2017_08 "Drer\ndnfl, Drer\ndnf" - Cele\ndnf-1 Xtro\ndnf Mmus\Ndnf Hsap\NDNF "learning defective,memory defective,viable" FBgn0041130 l(2)45Af lethal (2) 45Af http://flybase.org/reports/FBgn0041130 gene - - - l(2)45Af - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0004096 l(2)60Dd lethal (2) 60Dd http://flybase.org/reports/FBgn0004096 - gene - - - l(2)60Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0060462 l(3)S115510a lethal (3) S115510a http://flybase.org/reports/FBgn0060462 gene - - - l(3)S115510a - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267965 CR46245 - http://flybase.org/reports/FBgn0267965 non_protein_coding_gene - - - "CR46245, Dm_X:36005" - CR46245 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069445 E(br)444 E(br)444 http://flybase.org/reports/FBgn0069445 gene - - - E(br)444 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,semidominant" leg FBgn0003191 ra rase http://flybase.org/reports/FBgn0003191 - gene - - - ra - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "head bristle,scutellar bristle,macrochaeta,microchaeta,thorax,head" FBgn0034506 CG13870 - http://flybase.org/reports/FBgn0034506 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13870 - CG13870 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035761 RhoGEF4 Rho guanine nucleotide exchange factor 4 http://flybase.org/reports/FBgn0035761 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from direct assay positive regulation of stress fiber assembly ; GO:0051496 | inferred from direct assay positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG8606, RhoGEF4, DRhoGEF4, RhoGEF" "IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG8606 11-Aug-17 DroID_v2017_08 "Drer\net1, Drer\fgd1, Drer\arhgef39, Drer\fgd4a, Drer\LOC793364, Drer\fgd" "Scer\ROM2, Scer\FUS2, Scer\CDC24, Scer\ROM1" "Cele\exc-5, Cele\tag-52" "Xtro\fgd4, Xtro\spata13, Xtro\arhgef39" "Mmus\Arhgef38, Mmus\Arhgef4, Mmus\Fgd2, Mmus\Fgd4, Mmus\Fgd1, Mmus\Arhgef39, Mmus\Spata13, Mmus\Fgd3" "Hsap\FGD1, Hsap\FGD6, Hsap\ARHGEF39, Hsap\SPATA13, Hsap\FGD3, Hsap\ARHGEF38, Hsap\FGD4, Hsap\FGD2" "viable,fertile" FBgn0058265 CG40265 - http://flybase.org/reports/FBgn0058265 protein_coding_gene - - - CG40265 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040795 CG13038 - http://flybase.org/reports/FBgn0040795 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13038 - CG13038 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0024698 Cpsf160 Cleavage and polyadenylation specificity factor 160 http://flybase.org/reports/FBgn0024698 "FBgn0024812, FBgn0033941, FBgn0062164" protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000068525 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A mRNA 3'-UTR binding ; GO:0003730 | inferred from sequence or structural similarity with UniProtKB:Q10570 mRNA cleavage ; GO:0006379 | inferred from biological aspect of ancestor with PANTHER:PTN000068525 mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with UniProtKB:Q10570 mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000068525 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from sequence or structural similarity with UniProtKB:Q10570 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from sequence or structural similarity with UniProtKB:Q10570 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000068526 "CG10110, Cpsf, dCPSF-160, CPSF, anon-WO0118547.217, Cpsf160, CPSF160, cpsf, CPSF-160" "IPR004871:Cleavage/polyadenylation specificity factor, A subunit, C-terminal, IPR015943:WD40/YVTN repeat-like-containing domain" CG10110 11-Aug-17 DroID_v2017_08 Drer\cpsf1 Scer\CFT1 Cele\cpsf-1 Xtro\cpsf1 Mmus\Cpsf1 Hsap\CPSF1 " embryonic stage--pupal stage , adult stage | male , adult stage | female " "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "hypostomal sclerite,embryonic/first instar larval cuticle,embryonic/larval neuroblast,ganglion mother cell" FBgn0024595 ziplock ziplock http://flybase.org/reports/FBgn0024595 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available ziplock - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029989 CG15333 - http://flybase.org/reports/FBgn0029989 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18293, CG15333" IPR006610:Domain of unknown function DM7 CG15333 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC18153 K 0.743692422 0.563382824 -0.14482529 0.387112552 0.732416646 2.723764001 FBgn0052181 CG32181 - http://flybase.org/reports/FBgn0052181 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT19257, CG32181" - CG32181 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040668 CG17409 - http://flybase.org/reports/FBgn0040668 protein_coding_gene - - - CG17409 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004770 l(3)89Ei lethal (3) 89Ei http://flybase.org/reports/FBgn0004770 - gene - - - l(3)89Ei - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020248 stet stem cell tumor http://flybase.org/reports/FBgn0020248 "FBgn0035221, FBgn0035223, FBgn0041725, FBgn0053166" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 "protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 male germ-line stem cell population maintenance ; GO:0036098 | inferred from genetic interaction with UniProtKB:A1YK24,UniProtKB:B8A421,UniProtKB:Q9VCH5" integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001117493 "CG12083, Rho2, Brho, Rho-2, brho, rho-2, CG12504, CG33166, stet, B-Rho, rho2" "IPR002610:Peptidase S54, rhomboid, IPR011992:EF-hand domain pair, IPR017213:Peptidase S54, rhomboid, metazoan, IPR002048:EF-hand domain, IPR022764:Peptidase S54, rhomboid domain" CG33166 11-Aug-17 DroID_v2017_08 "Drer\rhbdl3, Drer\rhbdl2, Drer\rhbdl1" - "Cele\rom-1, Cele\rom-2" "Xtro\LOC101732375, Xtro\rhbdl2" "Mmus\Rhbdl1, Mmus\Rhbdl2, Mmus\Rhbdl3" "Hsap\RHBDL3, Hsap\RHBDL1, Hsap\RHBDL2" "viable,female sterile,recessive,fertile,male sterile" "testis,germline clone,germarium,spectrosome | supernumerary,spectrosome | germline clone | supernumerary,male germline stem cell,male germline cell,hub cell,cyst cell,female germline stem cell,egg chamber,ovariole,ovarian sheath cell,wing vein,ectopic,chorion,dorsal appendage,wing" DRSC08283 IE -0.839401677 1.538255786 1.685114917 -0.897983874 -0.044453521 -0.212339295 FBgn0085407 Pvf3 PDGF- and VEGF-related factor 3 http://flybase.org/reports/FBgn0085407 protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR000072 vascular endothelial growth factor receptor binding ; GO:0005172 | inferred from sequence or structural similarity with HGNC:12680 "hemocyte migration ; GO:0035099 | traceable author statement synaptic target recognition ; GO:0008039 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from genetic interaction with Pvf2 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from expression pattern inferred from genetic interaction with Pvf1, Pvf2 vascular endothelial growth factor receptor signaling pathway ; GO:0048010 | inferred from sequence or structural similarity with HGNC:12680" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000072 "pvf3, CG34378, CG13783, PVF, CG4492, VEGF, PVFs, VEGF27Ca, CG13782, CG13781, Vegf27Ca, DmVEGF-3, CG31629, Pvf3, PVF3, Pvf" "IPR000072:PDGF/VEGF domain, IPR029034:Cystine-knot cytokine" CG34378 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 9-11 , embryonic stage | stage 11-13 , embryonic stage | stage 9-15 " " posterior ectoderm

restricted , Malpighian tubule

, embryonic hindgut

, embryonic foregut

, ventral nerve cord

" """DRSC02284, DRSC02286"" " IK FBgn0014911 anon-4Fe anon-4Fe http://flybase.org/reports/FBgn0014911 - gene - - - anon-4Fe - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267725 CR46058 - http://flybase.org/reports/FBgn0267725 non_protein_coding_gene - - - CR46058 - CR46058 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260113 2L3807 - http://flybase.org/reports/FBgn0260113 gene - - - 2L3807 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0053290 CG33290 - http://flybase.org/reports/FBgn0053290 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33290 - CG33290 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034441 CG10081 - http://flybase.org/reports/FBgn0034441 protein_coding_gene - - - CG10081 IPR007484:Peptidase M28 CG10081 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\APE3, Scer\VPS70, Scer\PFF1, Scer\YDR415C" "Cele\B0495.7, Cele\C44B7.11" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0027148 l(3)71CDb lethal (3) 71CDb http://flybase.org/reports/FBgn0027148 - gene - - - l(3)71CDb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014358 ms(3)HB665 ms(3)HB665 http://flybase.org/reports/FBgn0014358 - gene - - - ms(3)HB665 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005472 l(1)ts875 lethal (1) ts875 http://flybase.org/reports/FBgn0005472 - gene - - - l(1)ts875 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0011196 l(1)302-11 lethal (1) 302-11 http://flybase.org/reports/FBgn0011196 FBgn0010202 gene - - - "302-11, l(1)302-11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260815 EY10546 - http://flybase.org/reports/FBgn0260815 gene - - - EY10546 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030793 CG9125 - http://flybase.org/reports/FBgn0030793 protein_coding_gene 5'-3' exonuclease activity ; GO:0008409 | inferred from sequence or structural similarity with MGI:MGI:1890444 mRNA catabolic process ; GO:0006402 | inferred from sequence or structural similarity with MGI:MGI:1890444 nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:1890444 "CG32566, CG9125, dRai1, Rai1" IPR013961:RAI1-like CG9125 11-Aug-17 DroID_v2017_08 Drer\dxo "Scer\DXO1, Scer\RAI1" "Cele\Y47H10A.4, Cele\M01G12.9, Cele\M01G12.14, Cele\F07H5.10, Cele\eol-1, Cele\Y47H10A.3, Cele\Y47H10A.5, Cele\C37H5.14, Cele\M01G12.7, Cele\dom-3" Xtro\dxo Mmus\Dxo Hsap\DXO FBgn0031142 r-cup ryder cup http://flybase.org/reports/FBgn0031142 protein_coding_gene - - - "CG10998, r-cup" IPR011990:Tetratricopeptide-like helical domain CG10998 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004426 LysC Lysozyme C http://flybase.org/reports/FBgn0004426 FBgn0002575 pseudogene_attribute lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 - - "LysC, lysC, CG9111, CR9111, Lys C" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CR9111 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , larval stage && adult stage , larval stage " " adult midgut

, embryonic/larval midgut

" FBgn0265576 CG44403 - http://flybase.org/reports/FBgn0265576 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44403 - CG44403 11-Aug-17 DroID_v2017_08 - - - Xtro\lbhd1 Mmus\1810009A15Rik Hsap\LBHD1 FBgn0003195 r(ADH) regulator of ADH http://flybase.org/reports/FBgn0003195 - gene - - - "r[26-43], r(ADH)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266433 CG45063 - http://flybase.org/reports/FBgn0266433 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR008250 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250 - - "CG45063, CG3701" "IPR008250:P-type ATPase, A domain, IPR004014:Cation-transporting P-type ATPase, N-terminal" CG45063 11-Aug-17 DroID_v2017_08 "Drer\atp1a1a.1, Drer\atp1a3a, Drer\atp1a1b, Drer\atp2a3, Drer\atp1a1a.5, Drer\atp1a1a.3, Drer\si:dkey-28b4.8, Drer\atp2a2a, Drer\atp1a3b, Drer\atp2a1, Drer\atp2a2b, Drer\atp1a1a.4, Drer\atp1a2a, Drer\atp2a1l, Drer\atp1a1a.2" "Scer\PMA1, Scer\PMR1" "Cele\catp-3, Cele\sca-1, Cele\eat-6" "Xtro\atp12a, Xtro\atp1a3, Xtro\atp4a, Xtro\atp1a2, Xtro\atp1a1" "Mmus\Atp1a4, Mmus\Atp12a, Mmus\Atp2a1, Mmus\Atp4a, Mmus\Atp1a2, Mmus\Atp2a2, Mmus\Atp1a3, Mmus\Atp1a1, Mmus\Atp2a3" "Hsap\ATP1A2, Hsap\ATP4A, Hsap\ATP12A, Hsap\ATP1A3, Hsap\ATP1A4, Hsap\ATP1A1, Hsap\ATP2A1, Hsap\ATP2A2, Hsap\ATP2A3" FBgn0004933 a(2)48 abnormal abdomen (2) 48 http://flybase.org/reports/FBgn0004933 - gene - - - a(2)48 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,good,fertile,maternal effect,wild-type" "tergite,sternite,adult abdomen" FBgn0053271 CG33271 - http://flybase.org/reports/FBgn0053271 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6100, CG14139, CG32084, CG33271" - CG33271 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031034 CG14205 - http://flybase.org/reports/FBgn0031034 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG14205 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG14205 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-50, Cele\oac-14, Cele\oac-7, Cele\oac-20, Cele\oac-5, Cele\oac-9, Cele\oac-53, Cele\oac-46, Cele\oac-3, Cele\oac-31, Cele\nrf-6, Cele\oac-54, Cele\oac-32, Cele\oac-6, Cele\ndg-4, Cele\rhy-1, Cele\oac-55, Cele\oac-39" Xtro\LOC101732251 Mmus\Oacyl - viable FBgn0262358 CG43056 - http://flybase.org/reports/FBgn0262358 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43056 - CG43056 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032771 CG17349 - http://flybase.org/reports/FBgn0032771 protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from sequence or structural similarity with HGNC:19152 negative regulation of cell death ; GO:0060548 | inferred from sequence or structural similarity with HGNC:19152 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:19152 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:19152 "anon-WO0140519.204, CG17349" "IPR016024:Armadillo-type fold, IPR019399:Parkin co-regulated protein, IPR011989:Armadillo-like helical" CG17349 11-Aug-17 DroID_v2017_08 Drer\pacrg - Cele\E04F6.2 "Xtro\pacrgl, Xtro\pacrg" "Mmus\Pacrg, Mmus\Pacrgl" "Hsap\PACRGL, Hsap\PACRG" viable FBgn0019765 l(1)56 lethal (1) 56 http://flybase.org/reports/FBgn0019765 - gene - - - l(1)56 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002875 Mu(f[3N]) Mutator of forked-3N http://flybase.org/reports/FBgn0002875 - gene - - - Mu(f[3N]) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035110 thoc7 thoc7 http://flybase.org/reports/FBgn0035110 protein_coding_gene - mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR008501 mRNA export from nucleus in response to heat stress ; GO:0031990 | inferred by curator from GO:0000347 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000381981 cell proliferation ; GO:0008283 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype "THO complex part of transcription export complex ; GO:0000445 | inferred from biological aspect of ancestor with PANTHER:PTN000381981 THO complex ; GO:0000347 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:29874 protein complex ; GO:0043234 | inferred from physical interaction with thoc5, Hpr1 chromosome, telomeric region ; GO:0000781 | inferred from biological aspect of ancestor with PANTHER:PTN000381981" "THOC7, CG17143, thoc7, Thoc7" IPR008501:THO complex subunit 7/Mft1 CG17143 11-Aug-17 DroID_v2017_08 Drer\thoc7 - Cele\B0513.2 Xtro\thoc7 Mmus\Thoc7 Hsap\THOC7 "viable,female fertile" FBgn0266155 CR44861 - http://flybase.org/reports/FBgn0266155 non_protein_coding_gene - - - CR44861 - CR44861 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027843 CAH2 Carbonic anhydrase 2 http://flybase.org/reports/FBgn0027843 FBgn0036261 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from direct assay one-carbon metabolic process ; GO:0006730 | inferred from direct assay intrinsic component of external side of plasma membrane ; GO:0031233 | inferred from sequence model "CG6906, CT21171, CAH2" "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class" CG6906 11-Aug-17 DroID_v2017_08 "Drer\ca4a, Drer\ca9, Drer\ca8, Drer\zgc:153760, Drer\si:ch211-173d10.4, Drer\ca6, Drer\car15, Drer\ca2, Drer\cahz, Drer\ca10a, Drer\ca12, Drer\ca15c, Drer\ca4b, Drer\ca7, Drer\ca10b, Drer\ca14, Drer\ca4c, Drer\ca15a, Drer\ca16b, Drer\ca5a, Drer\ptprga, Drer\ca15b" - "Cele\cah-3, Cele\cah-5, Cele\cah-6, Cele\cah-4" "Xtro\ca12, Xtro\ca7, Xtro\ca8, Xtro\ca10, Xtro\ca11, Xtro\ca2, Xtro\ca1, Xtro\ca3, Xtro\LOC779564, Xtro\ca4, Xtro\ca14, Xtro\ca5b, Xtro\ca6" "Mmus\Car10, Mmus\Car1, Mmus\Car5b, Mmus\Car2, Mmus\Car12, Mmus\Car4, Mmus\Car8, Mmus\Car11, Mmus\Car3, Mmus\Car6, Mmus\Car7, Mmus\Car13, Mmus\Car9, Mmus\Car15, Mmus\Ptprg, Mmus\Car14, Mmus\Car5a" "Hsap\CA9, Hsap\CA10, Hsap\CA1, Hsap\CA11, Hsap\CA5B, Hsap\CA12, Hsap\CA4, Hsap\CA2, Hsap\CA6, Hsap\CA7, Hsap\PTPRG, Hsap\CA3, Hsap\CA14, Hsap\CA5A, Hsap\CA8, Hsap\CA13" viable FBgn0001621 l(1)dh1 lethal (1) discs heterogeneous 1 http://flybase.org/reports/FBgn0001621 - gene - - - "l(1)d.het.-1, l(1)dh1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" ventral thoracic disc FBgn0016070 smg smaug http://flybase.org/reports/FBgn0016070 FBgn0010432 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR015327 translation repressor activity ; GO:0030371 | inferred from direct assay mRNA 3'-UTR binding ; GO:0003730 | traceable author statement mRNA binding ; GO:0003729 | traceable author statement translation repressor activity ; GO:0030371 | traceable author statement translation repressor activity, nucleic acid binding ; GO:0000900 | traceable author statement myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR015327 negative regulation of translation ; GO:0017148 | traceable author statement nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype establishment of RNA localization ; GO:0051236 | inferred from mutant phenotype positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from mutant phenotype regulation of mRNA stability ; GO:0043488 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay" cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "SMG, CG5263, Smg, D69, anonD69, anon-D69, smg, Smaug, SmG, smaug" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain, IPR015327:Smaug, pseudo-HEAT analogous topology, IPR016024:Armadillo-type fold" CG5263 11-Aug-17 DroID_v2017_08 "Drer\samd4a, Drer\zcchc14" Scer\VTS1 Cele\ZC190.4 "Xtro\samd4b, Xtro\samd4a" "Mmus\Samd4b, Mmus\Samd4, Mmus\Zcchc14" "Hsap\SAMD4A, Hsap\SAMD4B, Hsap\ZCCHC14" "viable,fertile,wild-type,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,neuroanatomy defective" "syncytial blastoderm embryo,maternal effect,cycle 11 embryo,class IV dendritic arborizing neuron,ovary,class IV dendritic arborizing neuron | third instar larval stage" DRSC28033 K 0.573015392 0.231406075 0.31387203 -0.17976781 -2.340000303 0.592201943 FBgn0052190 NUCB1 NUCB1 http://flybase.org/reports/FBgn0052190 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011330 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR011330 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern Golgi apparatus ; GO:0005794 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG5587, nucb1, CG32190, NUCB1, NucB1" "IPR018247:EF-Hand 1, calcium-binding site, IPR011992:EF-hand domain pair, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel" CG32190 11-Aug-17 DroID_v2017_08 "Drer\nucb1, Drer\nucb2b, Drer\nucb2a" Scer\SSP120 Cele\nucb-1 "Xtro\nucb1, Xtro\nucb2" "Mmus\Nucb2, Mmus\Nucb1" "Hsap\GOLGA6L1, Hsap\NUCB1, Hsap\NUCB2" " embryonic stage | stage >=11 , embryonic stage | early " " embryonic/larval salivary gland

,

ubiquitous " embryonic stage embryonic/larval salivary gland

"viable,fertile" FBgn0264956 CR44125 - http://flybase.org/reports/FBgn0264956 non_protein_coding_gene - - - "lincRNA.250, CR44125" - CR44125 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065981 iab-5PRE iab-5 Polycomb group response element http://flybase.org/reports/FBgn0065981 regulatory_region - - - iab-5PRE - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011956 tRNA:Arg-ACG-1-3 transfer RNA:Arginine-ACG 1-3 http://flybase.org/reports/FBgn0011956 "FBgn0003757, FBgn0011947, FBgn0050314, FBgn0060089" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "tRNA Arg, tRNA[arg], tRNA[Arg][[2]], tRNA[Arg], AE002769.trna16-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002769-d, tRNA:arg2:42Ab, CR30314, chr2R.trna8-ArgACG, tRNA-Arg-ACG-1-3, tRNA:Arg-ACG-1-3, tRNA:R2:42Ab, CGU" - CR30314 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262784 roX1::Dpse\roX1 - http://flybase.org/reports/FBgn0262784 engineered_fusion_gene - - - roX1::Dpse\roX1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062615 Mod(var)1259 Mod(var)1259 http://flybase.org/reports/FBgn0062615 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1259, Mod(var)1259" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0069148 mcl(3)Z3808 mcl(3)Z3808 http://flybase.org/reports/FBgn0069148 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3808 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0003245 r(alphaGPDH) regulator of alpha GPDH http://flybase.org/reports/FBgn0003245 - gene - - - "m[alpha-GPDH], r[3-55.4], m(GPDH), r(alphaGPDH)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033702 CG8854 - http://flybase.org/reports/FBgn0033702 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8854 - CG8854 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029051 l(1)G0458 lethal (1) G0458 http://flybase.org/reports/FBgn0029051 gene - - - l(1)G0458 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0005488 l(1)ts1901 lethal (1) ts1901 http://flybase.org/reports/FBgn0005488 - gene - - - l(1)ts1901 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0014264 l(2)k04301a lethal (2) k04301a http://flybase.org/reports/FBgn0014264 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc growth ; GO:0007446 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)k00202, l(2)43/1, l(2)k04301, l(2)k04301a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,hyperplasia,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval brain,prothoracic leg disc,mesothoracic leg disc,metathoracic leg disc" FBgn0261274 Ero1L Endoplasmic reticulum oxidoreductin-1-like http://flybase.org/reports/FBgn0261274 protein_coding_gene "oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ; GO:0016671 | inferred from electronic annotation with InterPro:IPR007266 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with UniProtKB:Q96HE7" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR007266 protein folding in endoplasmic reticulum ; GO:0034975 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 chaperone mediated protein folding requiring cofactor ; GO:0051085 | inferred from sequence or structural similarity with UniProtKB:Q96HE7 cellular protein modification process ; GO:0006464 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q96HE7 "kiga, ERO1-L, CG1333, Ero1L, l(3)SH22, l(3)64Ag, Ero1l, ero1L" IPR007266:Endoplasmic reticulum oxidoreductin 1 CG1333 11-Aug-17 DroID_v2017_08 "Drer\ero1a, Drer\ero1b" Scer\ERO1 Cele\ero-1 "Xtro\ero1a, Xtro\ero1b" "Mmus\Ero1l, Mmus\Ero1lb" "Hsap\ERO1B, Hsap\ERO1A" FBgn0033894 CG13352 - http://flybase.org/reports/FBgn0033894 protein_coding_gene - - - CG13352 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035585 ATPsynCF6L "ATP synthase, coupling factor 6-like" http://flybase.org/reports/FBgn0035585 protein_coding_gene hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from electronic annotation with InterPro:IPR008387 ATPase activity ; GO:0016887 | contributes_to inferred from sequence or structural similarity with HGNC:847 ATP synthesis coupled proton transport ; GO:0015986 | inferred from electronic annotation with InterPro:IPR008387 ATP metabolic process ; GO:0046034 | inferred from sequence or structural similarity with RGD:621376 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with RGD:621376" "CG12027, ATPR, ATPsynCF6L" "IPR008387:ATP synthase-coupling factor 6, mitochondrial" CG12027 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-22n8.3, Drer\si:ch211-140m22.7, Drer\atp5j" - Cele\atp-4 Xtro\atp5j Mmus\Atp5j Hsap\ATP5J DRSC08232 I 1.950521044 0.614457678 0.223087393 0.220130787 0.276438355 -0.33536531 FBgn0051803 CG31803 - http://flybase.org/reports/FBgn0051803 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium movement involved in cell motility ; GO:0060294 | inferred from biological aspect of ancestor with PANTHER:PTN000498841 axoneme assembly ; GO:0035082 | inferred from biological aspect of ancestor with PANTHER:PTN000498841 motile cilium assembly ; GO:0044458 | inferred from biological aspect of ancestor with PANTHER:PTN000498841 cellular_component ; GO:0005575 | no biological data available "BcDNA:AT29119, CG31803" - CG31803 11-Aug-17 DroID_v2017_08 Drer\rsph9 - - Xtro\rsph9 Mmus\Rsph9 Hsap\RSPH9 partially lethal - majority die FBgn0263523 mir-4972 mir-4972 stem loop http://flybase.org/reports/FBgn0263523 miRNA_gene - - - "mir-4972, dme-mir-4972, CR43508" - CR43508 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266989 CR45440 - http://flybase.org/reports/FBgn0266989 non_protein_coding_gene - - - CR45440 - CR45440 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265076 CR44187 - http://flybase.org/reports/FBgn0265076 non_protein_coding_gene - - - CR44187 - CR44187 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052167 CG32167 - http://flybase.org/reports/FBgn0052167 protein_coding_gene - - - CG32167 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040133 l(2)22Af lethal (2) 22Af http://flybase.org/reports/FBgn0040133 gene - - - "T, l(2)22Af" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005405 l(1)10Ch lethal (1) 10Ch http://flybase.org/reports/FBgn0005405 - gene - - - "l(1)JC35, l(1)10Ch" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036498 CG13455 - http://flybase.org/reports/FBgn0036498 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13455 - CG13455 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0026876 CG11403 - http://flybase.org/reports/FBgn0026876 - protein_coding_gene "ATP-dependent DNA helicase activity ; GO:0004003 | inferred from electronic annotation with InterPro:IPR006554, InterPro:IPR010614 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006555, InterPro:IPR010614, InterPro:IPR014013 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR010614 helicase activity ; GO:0004386 | inferred from sequence or structural similarity" nucleobase-containing compound metabolic process ; GO:0006139 | inferred from electronic annotation with InterPro:IPR006555 - "EG:33C11.2, cg11403, CG11403" "IPR006555:ATP-dependent helicase, C-terminal, IPR013020:DNA helicase (DNA repair), Rad3 type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014013:Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, IPR010614:DEAD2, IPR006554:Helicase-like, DEXD box c2 type" CG11403 11-Aug-17 DroID_v2017_08 Drer\ddx11 Scer\CHL1 Cele\chl-1 Xtro\ddx11 Mmus\Ddx11 Hsap\DDX11 "viable,fertile" FBgn0027183 l(2)60A-K lethal (2) 60A-K http://flybase.org/reports/FBgn0027183 - gene - - - l(2)60A-K - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010014 CanB Calcineurin B http://flybase.org/reports/FBgn0010014 "FBgn0004466, FBgn0029757, FBgn0047037" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium-dependent protein serine/threonine phosphatase regulator activity ; GO:0008597 | inferred from sequence or structural similarity calmodulin binding ; GO:0005516 | inferred from sequence or structural similarity calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype calcineurin complex ; GO:0005955 | inferred from sequence or structural similarity synaptic vesicle ; GO:0008021 | non-traceable author statement "Calcineurin B, canB-4F, CNB, dCnB1, BcDNA:RH11383, Can, CG4209, CanB, CnB, CaNB" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG4209 11-Aug-17 DroID_v2017_08 "Drer\chp1, Drer\LOC100536377, Drer\tescb, Drer\chp2, Drer\wdr92, Drer\ppp3r1b, Drer\tesca, Drer\ppp3r1a" Scer\CNB1 Cele\cnb-1 "Xtro\chp1, Xtro\wdr92, Xtro\ppp3r1, Xtro\cib1" "Mmus\Chp1, Mmus\Chp2, Mmus\Ppp3r2, Mmus\Tescl, Mmus\Cib1, Mmus\Tesc, Mmus\Wdr92, Mmus\Ppp3r1, Mmus\Cib4" "Hsap\CIB1, Hsap\CHP2, Hsap\PPP3R1, Hsap\CIB4, Hsap\WDR92, Hsap\TESC, Hsap\CHP1, Hsap\PPP3R2" embryonic stage "viable,fertile,wild-type,sleep defective,locomotor behavior defective" FBgn0267992 CR46259 - http://flybase.org/reports/FBgn0267992 non_protein_coding_gene - - - CR46259 - CR46259 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038448 CG12783 - http://flybase.org/reports/FBgn0038448 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 CG12783 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG12783 11-Aug-17 DroID_v2017_08 "Drer\slc22a13, Drer\LOC101884074, Drer\slc22a7b.1, Drer\LOC100334012, Drer\slc22a6l, Drer\slc22a7b.2, Drer\svopa, Drer\slc22a21, Drer\slc22a7b.3, Drer\sv2, Drer\sv2ba, Drer\sv2bb, Drer\svopl, Drer\sv2c, Drer\slc22a5, Drer\sv2a, Drer\zgc:175176, Drer\zmp:0000001102, Drer\svopb, Drer\oatx" "Scer\FLR1, Scer\TPO1, Scer\QDR3, Scer\TPO3, Scer\DTR1, Scer\QDR2, Scer\AQR1, Scer\QDR1, Scer\YHK8, Scer\TPO2" Cele\svop-1 "Xtro\sv2b, Xtro\slc22a6" "Mmus\Slc22a28, Mmus\Slc22a2, Mmus\Sv2c, Mmus\Svop, Mmus\Slc22a20, Mmus\Slc22a23, Mmus\Slc22a6, Mmus\Sv2a, Mmus\Slc22a22, Mmus\Slc22a19, Mmus\Slc22a30, Mmus\Slc22a7, Mmus\Slc22a29, Mmus\Sv2b, Mmus\Svopl, Mmus\Slc22a8, Mmus\Slc22a27, Mmus\Slc22a16, Mmus\Slc22a4, Mmus\Slc22a26, Mmus\Slc22a14" "Hsap\SVOPL, Hsap\SV2C, Hsap\SLC22A2, Hsap\SLC22A25, Hsap\SLC22A11, Hsap\SLC22A23, Hsap\SLC22A9, Hsap\SVOP, Hsap\SLC22A10, Hsap\SLC22A24, Hsap\SLC22A8, Hsap\SV2A, Hsap\SLC22A7, Hsap\SLC22A6, Hsap\SLC22A12, Hsap\SLC22A1, Hsap\SV2B" "viable,fertile" FBgn0024871 l(2)k09033 lethal (2) k09033 http://flybase.org/reports/FBgn0024871 - gene - - - l(2)k09033 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024722 Su(var)57D58D Su(var)57D58D http://flybase.org/reports/FBgn0024722 - gene - - - Su(var)57D58D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267971 Ir52e Ionotropic receptor 52e http://flybase.org/reports/FBgn0267971 protein_coding_gene - - - "Ir52e, IR52e" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033609 Fbl6 F-box and leucine-rich repeat protein 6 http://flybase.org/reports/FBgn0033609 protein_coding_gene SAM domain binding ; GO:0032093 | inferred from physical interaction with aop ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model regulation of protein stability ; GO:0031647 | inferred from direct assay positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:2000060 | inferred from direct assay SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:13603 "Fbl6, CG13213, FBXL6, fbl6" "IPR001810:F-box domain, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR006553:Leucine-rich repeat, cysteine-containing subtype" CG13213 11-Aug-17 DroID_v2017_08 "Drer\fbxl15, Drer\kdm2aa, Drer\kdm2ab, Drer\zgc:158376, Drer\fbxl6, Drer\si:dkey-192l18.9, Drer\fbxl17, Drer\fbxl4" Scer\GRR1 - "Xtro\fbxl12, Xtro\kdm2b, Xtro\fbxl4, Xtro\fbxl19" "Mmus\Fbxl17, Mmus\Lrrc29, Mmus\Kdm2b, Mmus\Fbxl21, Mmus\Fbxl6, Mmus\Fbxl19, Mmus\Fbxl4, Mmus\Kdm2a" "Hsap\FBXL19, Hsap\LRRC29, Hsap\KDM2A, Hsap\FBXL4, Hsap\KDM2B, Hsap\FBXL17, Hsap\FBXL6" "visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "trichogen cell,mesothoracic tergum" DRSC06335 I -1.556861459 0.621255344 0.942042203 0.1390746 -0.582396972 0.65945824 FBgn0061161 l(1)7Bg lethal (1) 7Bg http://flybase.org/reports/FBgn0061161 gene - - - l(1)7Bg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020318 anon-86Fa anon-86Fa http://flybase.org/reports/FBgn0020318 - gene - - - "1D10, anon-86Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000029 AcpB Accessory gland protein B http://flybase.org/reports/FBgn0000029 - gene - - - AcpB - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000945 fs(2)A15 female sterile (2) A15 http://flybase.org/reports/FBgn0000945 - gene - - - fs(2)A15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "ovary,oocyte" FBgn0040353 CG14417 - http://flybase.org/reports/FBgn0040353 protein_coding_gene - - - "EG:BACR43E12.6, CG14417" - CG14417 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0000767 fs(1)A1024 female sterile (1) A1024 http://flybase.org/reports/FBgn0000767 - gene - - - fs(1)A1024 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of pupal stage,rescuable maternal effect,some die during pupal stage" wing FBgn0039386 CG5948 - http://flybase.org/reports/FBgn0039386 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 superoxide dismutase activity ; GO:0004784 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001424 removal of superoxide radicals ; GO:0019430 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000000114 CG5948 "IPR001424:Superoxide dismutase, copper/zinc binding domain" CG5948 11-Aug-17 DroID_v2017_08 "Drer\sod1, Drer\sod3a" Scer\SOD1 "Cele\sod-4, Cele\sod-1, Cele\sod-5" "Xtro\sod1, Xtro\sod3" "Mmus\Sod1, Mmus\Sod3" "Hsap\SOD1, Hsap\SOD3" FBgn0051955 CG31955 - http://flybase.org/reports/FBgn0051955 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG31955 - CG31955 11-Aug-17 DroID_v2017_08 Drer\chtf18 Scer\CTF18 - Xtro\chtf18 Mmus\Chtf18 Hsap\CHTF18 viable FBgn0025931 hip57 hb-interacting protein 57 http://flybase.org/reports/FBgn0025931 - gene - - - hip57 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266873 CR45334 - http://flybase.org/reports/FBgn0266873 non_protein_coding_gene - - - CR45334 - CR45334 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260808 EP3-1199 - http://flybase.org/reports/FBgn0260808 gene - - - EP3-1199 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264375 CR43827 - http://flybase.org/reports/FBgn0264375 non_protein_coding_gene - - - CR43827 - CR43827 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037128 CG14572 - http://flybase.org/reports/FBgn0037128 protein_coding_gene - - - CG14572 IPR032011:Domain of unknown function DUF4794 CG14572 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265785 CG44574 - http://flybase.org/reports/FBgn0265785 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44574 - CG44574 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035069 CG3611 - http://flybase.org/reports/FBgn0035069 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT12780, CG3611" - CG3611 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053181 CG33181 - http://flybase.org/reports/FBgn0053181 protein_coding_gene cation transmembrane transporter activity ; GO:0008324 | inferred from electronic annotation with InterPro:IPR006667 cation transport ; GO:0006812 | inferred from electronic annotation with InterPro:IPR006667 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001045280 - "CG1521, CG33181, CG32714" "IPR006667:SLC41 divalent cation transporters, integral membrane domain" CG33181 11-Aug-17 DroID_v2017_08 "Drer\slc41a2b, Drer\LOC564564, Drer\slc41a2a, Drer\slc41a1" - "Cele\ZK1053.6, Cele\ZK185.2, Cele\K07H8.2" "Xtro\slc41a2, Xtro\slc41a3" "Mmus\Slc41a3, Mmus\Slc41a2, Mmus\Slc41a1" "Hsap\SLC41A3, Hsap\SLC41A1, Hsap\SLC41A2" viable FBgn0266732 CR45205 - http://flybase.org/reports/FBgn0266732 non_protein_coding_gene - - - CR45205 - CR45205 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031518 CG3277 - http://flybase.org/reports/FBgn0031518 protein_coding_gene "protein tyrosine kinase activity ; GO:0004713 | inferred from electronic annotation with InterPro:IPR020635 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR020635 protein phosphorylation ; GO:0006468 | non-traceable author statement" cellular_component ; GO:0005575 | no biological data available CG3277 "IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG3277 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-206d17.1, Drer\fgfr3, Drer\fgfrl1a, Drer\kdr, Drer\si:dkey-14o18.6, Drer\kita, Drer\tie1, Drer\pdgfrl, Drer\flt4, Drer\si:ch211-167j9.5, Drer\tada2b, Drer\csf1ra, Drer\styk1, Drer\fgfr1a, Drer\flt3, Drer\ret, Drer\kitb, Drer\tek, Drer\kdrl, Drer\csf1rb, Drer\pdgfra, Drer\pdgfrb, Drer\fgfr2, Drer\fgfr4, Drer\LOC569566, Drer\flt1, Drer\fgfrl1b" - "Cele\egl-15, Cele\kin-9, Cele\F09G2.1, Cele\ver-4, Cele\R151.1, Cele\F09A5.2, Cele\C24G6.2" "Xtro\fgfr1, Xtro\pdgfra, Xtro\fgfr3, Xtro\pdgfrl.2, Xtro\flt1, Xtro\csf1r, Xtro\tie1, Xtro\kdr, Xtro\fgfr4, Xtro\fgfrl1, Xtro\tada2b, Xtro\pdgfrl, Xtro\fgfr2, Xtro\styk1, Xtro\tek, Xtro\flt4, Xtro\ret" "Mmus\Tie1, Mmus\Fgfr1, Mmus\Fgfr4, Mmus\Tek, Mmus\Kdr, Mmus\Pdgfrb, Mmus\Fgfr2, Mmus\Flt4, Mmus\Flt3, Mmus\Tada2b, Mmus\Styk1, Mmus\Fgfr3, Mmus\Ret, Mmus\Kit, Mmus\Pdgfrl, Mmus\Csf1r, Mmus\Pdgfra, Mmus\Flt1, Mmus\Fgfrl1" "Hsap\FLT1, Hsap\FLT4, Hsap\KIT, Hsap\RET, Hsap\PDGFRL, Hsap\PDGFRB, Hsap\FGFR1, Hsap\TIE1, Hsap\TEK, Hsap\FGFR2, Hsap\FGFR4, Hsap\PDGFRA, Hsap\FGFR3, Hsap\FGFRL1, Hsap\TADA2B, Hsap\CSF1R, Hsap\KDR, Hsap\FLT3, Hsap\STYK1" viable FBgn0015025 CkIIalpha-i1 CKII-alpha subunit interactor-1 http://flybase.org/reports/FBgn0015025 - protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein kinase binding ; GO:0019901 | inferred from physical interaction with CkIIα RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000003381" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from electronic annotation with InterPro:IPR027755 nucleus ; GO:0005634 | inferred from sequence model nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 "CKIIalpha-I1, CkIIalpha-i1, CG6215, dCKIIalpha-i1, ZFP47, DmA35, CKIIalpha-iI" "IPR013087:Zinc finger C2H2-type, IPR027755:Transcription factor Ovo-like, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027775:C2H2- zinc finger protein family subset" CG6215 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-229b18.3, Drer\si:dkey-66i24.9, Drer\zbtb11, Drer\znf131, Drer\si:dkey-17e16.13, Drer\zgc:171929, Drer\ovol1" Scer\RPN4 "Cele\Y5F2A.4, Cele\M03D4.4, Cele\ztf-2, Cele\Y111B2A.10, Cele\lin-48, Cele\Y55F3AM.14" Xtro\zbtb11 "Mmus\Zfp131, Mmus\Ovol1, Mmus\Rest, Mmus\Zfp770, Mmus\Rpl24, Mmus\Ovol3, Mmus\Ovol2" "Hsap\OVOL3, Hsap\ZNF131, Hsap\OVOL2, Hsap\ZNF770, Hsap\REST, Hsap\ZBTB11, Hsap\OVOL1" viable FBgn0264474 CR43882 - http://flybase.org/reports/FBgn0264474 non_protein_coding_gene - - - CR43882 - CR43882 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259699 CG42353 - http://flybase.org/reports/FBgn0259699 protein_coding_gene - - - "CG42353, CG9216" - CG42353 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0031549 Spindly Spindly http://flybase.org/reports/FBgn0031549 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from mutant phenotype microtubule ; GO:0005874 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay "CG15415, Spindly" - CG15415 11-Aug-17 DroID_v2017_08 Drer\zgc:171223 - - Xtro\spdl1 Mmus\Spdl1 Hsap\SPDL1 DRSC00430 IE -0.053291631 -2.131649703 1.474836741 -4.287608382 -0.04942602 -0.959051599 FBgn0015931 dsRNABP5 ds-RNA binding protein 5 http://flybase.org/reports/FBgn0015931 - gene - - - "dsRNABP#5, dsRNABP5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262575 CG43115 - http://flybase.org/reports/FBgn0262575 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43115 IPR032145:Protein of unknown function DUF4818 CG43115 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022090 l(2)k07312b lethal (2) k07312b http://flybase.org/reports/FBgn0022090 - gene - - - l(2)k07312b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266435 CG45065 - http://flybase.org/reports/FBgn0266435 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" cellular_component ; GO:0005575 | no biological data available "CG45065, CG9517, Dm GMCepsilon1" "IPR012132:Glucose-methanol-choline oxidoreductase, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR023753:FAD/NAD(P)-binding domain" CG45065 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0062708 EP1020 EP1020 http://flybase.org/reports/FBgn0062708 gene - - - "EP(2)1020, EP1020" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031564 CG2816 - http://flybase.org/reports/FBgn0031564 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG2816 "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG2816 11-Aug-17 DroID_v2017_08 "Drer\tfpia, Drer\tfpi2, Drer\spint2, Drer\col6a4a, Drer\spint1a, Drer\spint1b, Drer\ambp, Drer\si:dkeyp-73b11.8, Drer\si:dkey-117n7.5" - "Cele\mec-9, Cele\mec-1, Cele\T21D12.7" "Xtro\spint2, Xtro\ambp, Xtro\tfpi2, Xtro\spint1" "Mmus\Wfdc6a, Mmus\Spint3, Mmus\Wfdc8, Mmus\Tfpi, Mmus\Spint4, Mmus\Wfdc6b, Mmus\Eppin, Mmus\Spint5, Mmus\Ambp, Mmus\Tfpi2, Mmus\Spint2, Mmus\Spint1" "Hsap\TFPI, Hsap\WFIKKN1, Hsap\WFDC6, Hsap\SPINT3, Hsap\SPINT2, Hsap\SPINT4, Hsap\WFDC8, Hsap\AMBP, Hsap\EPPIN-WFDC6, Hsap\SPINT1, Hsap\TFPI2" viable FBgn0069242 eca eclair http://flybase.org/reports/FBgn0069242 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence model positive regulation of Wnt protein secretion ; GO:0061357 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred from sequence model Golgi organization ; GO:0007030 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype positive regulation of protein exit from endoplasmic reticulum ; GO:0070863 | inferred from mutant phenotype positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype reproduction ; GO:0000003 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from sequence model endomembrane system ; GO:0012505 | inferred from direct assay "CG33104, CG9443, eca, ECA, p24, Eca" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG33104 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-255i20.3, Drer\tmed9, Drer\tmed4" "Scer\ERP5, Scer\ERP1, Scer\ERP6" "Cele\T08D2.1, Cele\Y60A3A.9" "Xtro\tmed4, Xtro\tmed9" "Mmus\Tmed9, Mmus\Tmed11, Mmus\Tmed4" "Hsap\TMED9, Hsap\TMED4" "behavior defective,recessive,viable,fertile,lethal,maternal effect,female sterile,male semi-sterile,germline clone,partially lethal - majority die,non-rescuable maternal effect,female semi-sterile" "embryonic/first instar larval cuticle,dorsal,germline clone,wing vein,ectopic,wing margin,somatic clone" FBgn0000501 dsp dispersed http://flybase.org/reports/FBgn0000501 - gene molecular_function ; GO:0003674 | no biological data available Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "dsp, Dsp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" Malpighian tubule FBgn0259611 B0613 - http://flybase.org/reports/FBgn0259611 gene - - - B0613 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing vein L3,wing" FBgn0036599 CG13044 - http://flybase.org/reports/FBgn0036599 protein_coding_gene - - - CG13044 IPR007614:Retinin-like protein CG13044 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011235 cuc cuckold http://flybase.org/reports/FBgn0011235 "FBgn0010534, FBgn0011243" gene - mating ; GO:0007618 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype - "l(2)03264, l(2)10607, ms(2)05158, ms(2)27CD, ms(2)06491, cuc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,male sterile,behavior defective,partially lethal - majority die" FBgn0024191 sip1 septin interacting protein 1 http://flybase.org/reports/FBgn0024191 FBgn0027543 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR022783 ATP-dependent RNA helicase activity ; GO:0004004 | contributes_to inferred from sequence or structural similarity with SGD:S000004416 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40797 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR022783 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 spliceosomal complex disassembly ; GO:0000390 | inferred from biological aspect of ancestor with PANTHER:PTN000596045" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2-type post-mRNA release spliceosomal complex ; GO:0071008 | inferred from biological aspect of ancestor with PANTHER:PTN000596045 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with UniProtKB:Q9UBB9 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "GH11690, CG7238, BcDNA:GH11690, sip1, Sip1" "IPR000467:G-patch domain, IPR024933:Septin and tuftelin interacting protein, IPR022159:Tuftelin interacting protein, N-terminal domain, IPR022783:GC-rich sequence DNA-binding factor domain" CG7238 11-Aug-17 DroID_v2017_08 Drer\tfip11 Scer\SPP382 Cele\stip-1 Xtro\tfip11 "Mmus\Tfip11, Mmus\Lime1" "Hsap\LIME1, Hsap\TFIP11" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0085557 CG41026 - http://flybase.org/reports/FBgn0085557 protein_coding_gene - - - CG41026 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067654 sd-14 sd-14 http://flybase.org/reports/FBgn0067654 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0025561 anon-36Ab anon-36Ab http://flybase.org/reports/FBgn0025561 - gene - - - "cDNA II, anon-36Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260242 ssar single-strand annealing reducer http://flybase.org/reports/FBgn0260242 gene - double-strand break repair via single-strand annealing ; GO:0045002 | inferred from mutant phenotype - ssar - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065346 l(2)SH1816 lethal (2) SH1816 http://flybase.org/reports/FBgn0065346 gene - - - "l(2)SH1816, l(2)SH2 1816" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265805 CR44594 - http://flybase.org/reports/FBgn0265805 non_protein_coding_gene - - - CR44594 - CR44594 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065455 l(2)SH1391 lethal (2) SH1391 http://flybase.org/reports/FBgn0065455 gene - - - "l(2)SH1391, l(2)SH2 1391" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085722 CG41615 - http://flybase.org/reports/FBgn0085722 protein_coding_gene - - - CG41615 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017622 Eig83B Eig83B http://flybase.org/reports/FBgn0017622 - gene - - - "Eig83, Eig83B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060502 l(3)S105611 lethal (3) S105611 http://flybase.org/reports/FBgn0060502 gene - - - "1056/11, l(3)S105611" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0051948 CG31948 - http://flybase.org/reports/FBgn0051948 protein_coding_gene - - - "CG9966, CG31948" "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain, IPR031961:Domain of unknown function DUF4780" CG31948 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037184 CG14450 - http://flybase.org/reports/FBgn0037184 protein_coding_gene - - - CG14450 - CG14450 11-Aug-17 DroID_v2017_08 Drer\tefm - - Xtro\tefm Mmus\Tefm Hsap\TEFM FBgn0069407 JJF230 JJF230 http://flybase.org/reports/FBgn0069407 gene - - - JJF230 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0044474 EP1493 EP1493 http://flybase.org/reports/FBgn0044474 gene - - - EP1493 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0261256 wiser wings scalloped-eyes rough http://flybase.org/reports/FBgn0261256 gene - - - wiser - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive,short lived,female sterile,locomotor behavior defective,visible" "wing,metathoracic tarsal segment,adult abdomen,metathoracic leg,ovary,eye" FBgn0052709 CG32709 - http://flybase.org/reports/FBgn0052709 protein_coding_gene - - - "BcDNA:HL05735, CG32709" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039527 CG5639 - http://flybase.org/reports/FBgn0039527 protein_coding_gene "serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223, InterPro:IPR004094" - extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR008197 "CT17816, CG5639" "IPR000716:Thyroglobulin type-1, IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR004094:Antistasin-like domain, IPR006150:Cysteine-rich repeat, IPR008197:WAP-type 'four-disulfide core' domain, IPR011061:Hirudin/antistatin, IPR003645:Follistatin-like, N-terminal, IPR028150:Lustrin, cysteine-rich repeated domain" CG5639 11-Aug-17 DroID_v2017_08 "Drer\tnr, Drer\fgb, Drer\zgc:158328, Drer\fgl2b, Drer\wfdc2, Drer\scube1, Drer\zgc:171687, Drer\tnw, Drer\fga, Drer\LOC100007488, Drer\crb2b, Drer\sned1, Drer\dpy19l1l, Drer\LOC100535882, Drer\si:ch211-287a12.9, Drer\si:zfos-2330d3.3, Drer\adgrl4, Drer\si:ch1073-110a20.3, Drer\si:ch211-157b11.8, Drer\fgg, Drer\angptl1a, Drer\tnxba, Drer\svep1, Drer\jag1b, Drer\si:ch73-173h19.3, Drer\angpt1, Drer\si:ch1073-110a20.2, Drer\tnc, Drer\angptl6, Drer\jag2a, Drer\si:zfos-2330d3.1, Drer\ltbp3, Drer\crb2a, Drer\angptl5, Drer\adgrf6, Drer\LOC100332841, Drer\angptl2b, Drer\matn3a, Drer\fibcd1, Drer\fbln7, Drer\LOC562634, Drer\col28a1a, Drer\angptl4, Drer\megf6b, Drer\angpt4, Drer\angptl2a, Drer\efemp1, Drer\angptl3, Drer\zmp:0000000846, Drer\fgl2a, Drer\wu:fj11g02, Drer\si:zfos-2330d3.6, Drer\jag1a, Drer\col28a1a, Drer\jag2b, Drer\dlb, Drer\angpt2b, Drer\si:zfos-2330d3.8, Drer\fbln1, Drer\si:ch211-203k16.3, Drer\scube3, Drer\si:ch1073-110a20.1, Drer\zgc:194887" - "Cele\Y69H2.10, Cele\Y43C5A.2, Cele\ensh-1, Cele\T15B7.1, Cele\C08G9.2, Cele\Y26D4A.12, Cele\W05B2.2, Cele\ZC504.1, Cele\Y69H2.3, Cele\K10D3.4" "Xtro\fcn3, Xtro\fcn1, Xtro\angptl3, Xtro\crb2, Xtro\angptl2, Xtro\svep1, Xtro\fibcd1, Xtro\LOC100497330, Xtro\angptl4, Xtro\f12, Xtro\tnr, Xtro\fgl1, Xtro\col14a1, Xtro\notch1, Xtro\angptl5, Xtro\fgb, Xtro\angpt1, Xtro\jag1, Xtro\fbn1, Xtro\fgl2, Xtro\tnc, Xtro\angpt4, Xtro\ltbp4, Xtro\tnxb, Xtro\tnn, Xtro\matn4, Xtro\hgfac, Xtro\fcn2, Xtro\fga, Xtro\LOC100491105, Xtro\LOC100488177, Xtro\mfap4, Xtro\fgg, Xtro\nell1" "Mmus\Fgl1, Mmus\Fcnb, Mmus\Wfdc17, Mmus\Fcna, Mmus\Dlk2, Mmus\Angpt2, Mmus\Svep1, Mmus\Angptl6, Mmus\Scube3, Mmus\Wfdc15a, Mmus\Wfdc9, Mmus\Wfdc10, Mmus\Angptl2, Mmus\Mfap4, Mmus\Angpt1, Mmus\Wfdc5, Mmus\Tdgf1, Mmus\Jag2, Mmus\Wap, Mmus\Angptl3, Mmus\Sned1, Mmus\Jag1, Mmus\Dll4, Mmus\Wfdc18, Mmus\Fbln7, Mmus\Fgg, Mmus\Tnc, Mmus\Wfdc2, Mmus\Dll3, Mmus\Wfdc11, Mmus\Tnxb, Mmus\Angptl4, Mmus\Col28a1, Mmus\Fgb, Mmus\Tnr, Mmus\Ltbp1, Mmus\Tnn, Mmus\Angptl7, Mmus\Fibcd1, Mmus\Slpi, Mmus\Hgfac, Mmus\Fga, Mmus\Egfl7, Mmus\Dlk1, Mmus\Hmcn2, Mmus\Wfdc16, Mmus\Vwce, Mmus\Angptl1, Mmus\Wfdc15b, Mmus\Vwde, Mmus\Ltbp4, Mmus\Wfdc13, Mmus\Wfdc12, Mmus\Wfdc21, Mmus\Megf6, Mmus\Col22a1, Mmus\Crb2, Mmus\Fbn1, Mmus\Scube2, Mmus\Angpt4, Mmus\Fgl2, Mmus\Matn3, Mmus\Cfc1, Mmus\Vwa1, Mmus\Habp2, Mmus\F12" "Hsap\TDGF1, Hsap\TNR, Hsap\FGL2, Hsap\MATN3, Hsap\ANGPTL3, Hsap\JAG1, Hsap\LOC100996717, Hsap\NOTCH2NL, Hsap\TNXB, Hsap\WFDC11, Hsap\DLK1, Hsap\FGA, Hsap\WFDC10B, Hsap\PI3, Hsap\CRB2, Hsap\SCUBE2, Hsap\FBLN7, Hsap\WFDC5, Hsap\FGG, Hsap\EYS, Hsap\WFDC13, Hsap\WFDC9, Hsap\EGFL7, Hsap\ANGPT4, Hsap\FCN3, Hsap\FGL1, Hsap\ANGPTL2, Hsap\ANGPTL5, Hsap\COL22A1, Hsap\CFC1B, Hsap\TNC, Hsap\WFDC12, Hsap\ANGPTL1, Hsap\ANGPTL4, Hsap\FCN2, Hsap\TG, Hsap\ANGPTL6, Hsap\DLL3, Hsap\VWA1, Hsap\SLPI, Hsap\JAG2, Hsap\FGB, Hsap\SNED1, Hsap\WFDC10A, Hsap\ANGPT2, Hsap\COL14A1, Hsap\ANGPT1, Hsap\VWCE, Hsap\TNN, Hsap\DLK2, Hsap\LTBP1, Hsap\SCUBE3, Hsap\WFDC2, Hsap\DLL4, Hsap\HGFAC, Hsap\F12, Hsap\SVEP1, Hsap\HABP2, Hsap\ANGPTL7, Hsap\FIBCD1, Hsap\CFC1" lethal FBgn0263241 Mocs1 Molybdenum cofactor synthesis 1 http://flybase.org/reports/FBgn0263241 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000385, InterPro:IPR006638, InterPro:IPR007197, InterPro:IPR013785 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR000385, InterPro:IPR010505 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000385, InterPro:IPR013483" Mo-molybdopterin cofactor biosynthetic process ; GO:0006777 | inferred from sequence or structural similarity with UniProtKB:Q9NZB8 molybdopterin synthase complex ; GO:0019008 | inferred from electronic annotation with InterPro:IPR010505 "Mocs1, Mosc1A+Mosc1B, mocsI, CG7858, CG33048, Mocs1B, Mocs1A-B, Mocs1A, MocsI, MOCS1A, MOCS1B, lxd, MOCSI" "IPR000385:MoaA/nifB/pqqE, iron-sulphur binding, conserved site, IPR002820:Molybdopterin cofactor biosynthesis C (MoaC) domain, IPR006638:Elongator protein 3/MiaB/NifB, IPR007197:Radical SAM, IPR010505:Molybdenum cofactor synthesis C-terminal, IPR013483:Molybdenum cofactor biosynthesis protein A, IPR013785:Aldolase-type TIM barrel, IPR023045:Molybdenum cofactor biosynthesis C, IPR034481:Main SPASM domain-containing" CG33048 11-Aug-17 DroID_v2017_08 Drer\mocs1 - "Cele\F49H6.5, Cele\F49E2.1" Xtro\mocs1 Mmus\Mocs1 Hsap\MOCS1 FBgn0062533 ff3 ff3 http://flybase.org/reports/FBgn0062533 gene - - - ff3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,meiotic cell cycle defective,male" "mitotic cell cycle,mitotic anaphase,mitotic telophase,cell cycle,nuclear chromosome" FBgn0000003 7SLRNA:CR32864 Signal recognition particle 7SL RNA CR32864 http://flybase.org/reports/FBgn0000003 - non_protein_coding_gene - SRP-dependent cotranslational protein targeting to membrane ; GO:0006614 | inferred from sequence or structural similarity "signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from sequence or structural similarity" "7SL RNA, CR32864, 7SLRNA:CR32864, 7SLRNA" - CR32864 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045865 blood\ORF1 blood element ORF1 http://flybase.org/reports/FBgn0045865 transposable_element_gene - - - blood\ORF1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013244 E(var)261 E(var)261 http://flybase.org/reports/FBgn0013244 - gene - - - E(var)261 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0010188 tu-36e tu-36e http://flybase.org/reports/FBgn0010188 - gene - - - tu-36e - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030896 CG12612 - http://flybase.org/reports/FBgn0030896 protein_coding_gene - - - CG12612 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085333 CG34304 - http://flybase.org/reports/FBgn0085333 protein_coding_gene - - - CG34304 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262611 CG43137 - http://flybase.org/reports/FBgn0262611 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43137, lincRNA.952" - CG43137 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069056 CG33226 - http://flybase.org/reports/FBgn0069056 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" cellular_component ; GO:0005575 | no biological data available "SP37, SPH37, CG10450, CG33226" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR001314:Peptidase S1A, chymotrypsin family, IPR033116:Serine proteases, trypsin family, serine active site" CG33226 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.9, Drer\cfd, Drer\ovch1, Drer\si:ch211-165b19.8, Drer\zgc:165423, Drer\si:dkey-16l2.17, Drer\gzm3, Drer\LOC100004427, Drer\zgc:163079, Drer\gzmk, Drer\si:ch211-165b19.5, Drer\zgc:92313, Drer\si:dkey-21e2.15, Drer\LOC558805, Drer\si:dkeyp-93a5.3, Drer\si:dkey-21e2.7, Drer\gzma, Drer\si:dkey-21e2.12" - "Cele\try-1, Cele\try-3, Cele\try-6" - "Mmus\Mcpt4, Mmus\Ctsg, Mmus\Gzmb, Mmus\Mcpt9, Mmus\Mcpt8, Mmus\Mcpt1, Mmus\Klk9, Mmus\Klk6, Mmus\Gzmc, Mmus\Gzmg, Mmus\Gzmf, Mmus\Cma1, Mmus\Gzme, Mmus\Gzmd, Mmus\Cma2, Mmus\Klk15" "Hsap\MASP1, Hsap\CMA1, Hsap\GZMB, Hsap\KLK15, Hsap\CTSG, Hsap\GZMH, Hsap\KLK9" FBgn0062691 EP1350 EP1350 http://flybase.org/reports/FBgn0062691 gene - - - "EP(X)1350, EP1350" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0260452 CG13984 - http://flybase.org/reports/FBgn0260452 protein_coding_gene - - - CG13984 - CG13984 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0062689 EP1388 EP1388 http://flybase.org/reports/FBgn0062689 gene - - - "EP(X)1388, EP1388" - - 11-Aug-17 DroID_v2017_08 - - - - - - spermatogonium FBgn0262543 CR43097 - http://flybase.org/reports/FBgn0262543 non_protein_coding_gene - - - "CG43097, CR43097" - CR43097 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014865 Mtk Metchnikowin http://flybase.org/reports/FBgn0014865 FBgn0061385 protein_coding_gene - defense response to fungus ; GO:0050832 | traceable author statement response to bacterium ; GO:0009617 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype antibacterial humoral response ; GO:0019731 | inferred from expression pattern defense response ; GO:0006952 | inferred from direct assay antifungal humoral response ; GO:0019732 | traceable author statement antifungal humoral response ; GO:0019732 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from expression pattern defense response to fungus ; GO:0050832 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | traceable author statement extracellular region ; GO:0005576 | inferred from direct assay "Mtk, Metch, METCH, metch, Metc, CG8175, mtk, metk, DIM 17, BcDNA:RH07954" IPR012513:Metchnikowin CG8175 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | 6-24 hr viable FBgn0038706 CG3517 - http://flybase.org/reports/FBgn0038706 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3517 - CG3517 11-Aug-17 DroID_v2017_08 - - - - - - "visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0005197 l(3)36d24 lethal (3) 36d24 http://flybase.org/reports/FBgn0005197 - gene - - - l(3)36d24 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261574 kug kugelei http://flybase.org/reports/FBgn0261574 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR002126, InterPro:IPR015919, InterPro:IPR018097 cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity calcium ion binding ; GO:0005509 | inferred from sequence model receptor activity ; GO:0004872 | inferred from sequence or structural similarity" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype establishment of planar polarity of follicular epithelium ; GO:0042247 | inferred from mutant phenotype calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype salivary gland development ; GO:0007431 | inferred from mutant phenotype negative regulation of imaginal disc growth ; GO:0045571 | traceable author statement homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from sequence or structural similarity open tracheal system development ; GO:0007424 | inferred from mutant phenotype establishment or maintenance of actin cytoskeleton polarity ; GO:0030950 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity basal plasma membrane ; GO:0009925 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "fat2, RE-A, kug, ftl, CG7749, DCad76E, Cad76E, CT23445, Ftl, kugel" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR001881:EGF-like calcium-binding domain, IPR002126:Cadherin, IPR013032:EGF-like, conserved site, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain" CG7749 11-Aug-17 DroID_v2017_08 "Drer\dchs1b, Drer\si:dkey-22o22.2, Drer\si:ch211-186j3.6, Drer\fat2, Drer\dchs1a, Drer\cdh23, Drer\fat1a, Drer\dchs2, Drer\fat3a, Drer\fat1b, Drer\LOC568600" - "Cele\cdh-1, Cele\fmi-1, Cele\cdh-4, Cele\hmr-1" "Xtro\fat1, Xtro\fat4, Xtro\dchs2" "Mmus\Fat4, Mmus\Fat2, Mmus\Fat3, Mmus\Cdh23, Mmus\Dchs1, Mmus\Fat1" "Hsap\CDH23, Hsap\DLK2, Hsap\FAT3, Hsap\FAT1, Hsap\FAT2, Hsap\DCHS2, Hsap\FAT4, Hsap\DCHS1" FBgn0265790 CR44579 - http://flybase.org/reports/FBgn0265790 non_protein_coding_gene - - - CR44579 - CR44579 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051513 CG31513 - http://flybase.org/reports/FBgn0051513 protein_coding_gene - - - CG31513 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC23522 K -0.00125279 -0.285870801 -0.528721533 0.850536889 1.842946422 -0.650106921 FBgn0060948 l(3)S037901 lethal (3) S037901 http://flybase.org/reports/FBgn0060948 gene - - - "0379/01, l(3)S037901" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0036198 crim crimpled http://flybase.org/reports/FBgn0036198 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype" septate junction ; GO:0005918 | inferred from direct assay "CG6038, crim, Crim" - CG6038 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "embryonic/larval dorsal trunk,trichogen cell" FBgn0001770 l(1)M41 lethal (1) M41 http://flybase.org/reports/FBgn0001770 - gene - - - l(1)M41 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260605 2L1561 - http://flybase.org/reports/FBgn0260605 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1561 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0024361 Tsp2A Tetraspanin 2A http://flybase.org/reports/FBgn0024361 - protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q0KHY3,UniProtKB:Q9VW87" establishment of endothelial intestinal barrier ; GO:0090557 | inferred from mutant phenotype establishment of endothelial barrier ; GO:0061028 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 smooth septate junction assembly ; GO:0090528 | inferred from mutant phenotype apicolateral plasma membrane ; GO:0016327 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 smooth septate junction ; GO:0005920 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "EG:8D8.7, CG11415, D8.7, Dm.Tsp2A, Tsp2A, tsp2A" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG11415 11-Aug-17 DroID_v2017_08 "Drer\tspan12, Drer\tspan11, Drer\cd151l" - Cele\tsp-20 Xtro\tspan2 "Mmus\Tspan11, Mmus\Tspan12, Mmus\Cd151" "Hsap\TSPAN12, Hsap\CD151, Hsap\TSPAN11" FBgn0263457 CR43480 - http://flybase.org/reports/FBgn0263457 non_protein_coding_gene - - - CR43480 - CR43480 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030060 CG2004 - http://flybase.org/reports/FBgn0030060 protein_coding_gene - - - CG2004 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG2004 11-Aug-17 DroID_v2017_08 - - "Cele\T16G1.3, Cele\F49C12.7, Cele\H37A05.2, Cele\C29F7.2, Cele\H06H21.8, Cele\nhr-246, Cele\E02C12.10, Cele\F59B1.8, Cele\C29F7.1, Cele\E02C12.6, Cele\E02C12.9, Cele\E02C12.8, Cele\F59B1.10, Cele\dhs-27, Cele\Y45G12C.4, Cele\F56A4.5" - - - viable FBgn0266781 CR45246 - http://flybase.org/reports/FBgn0266781 non_protein_coding_gene - - - CR45246 - CR45246 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262017 CG42830 - http://flybase.org/reports/FBgn0262017 protein_coding_gene transcription cofactor activity ; GO:0003712 | inferred from sequence or structural similarity with akirin positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with akirin nucleus ; GO:0005634 | inferred from sequence or structural similarity with akirin "CG7527, CG42830, anon-AE003656.1" IPR024132:Akirin CG42830 11-Aug-17 DroID_v2017_08 "Drer\akirin1, Drer\akirin2" - Cele\akir-1 "Xtro\akirin2, Xtro\akirin1" "Mmus\Akirin1, Mmus\Akirin2" "Hsap\AKIRIN1, Hsap\AKIRIN2" FBgn0028013 l(3)S108310a lethal (3) S108310a http://flybase.org/reports/FBgn0028013 gene - - - "1083/10, l(3)S108310, l(3)S108310a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022216 l(2)k03610 lethal (2) k03610 http://flybase.org/reports/FBgn0022216 - gene - - - l(2)k03610 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016897 l(3)64Cg lethal (3) 64Cg http://flybase.org/reports/FBgn0016897 - gene - - - l(3)64Cg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036138 CG14143 - http://flybase.org/reports/FBgn0036138 protein_coding_gene - - - "CG14143, chr3L_11128040_11128584.0" - CG14143 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065513 l(2)SH1164 lethal (2) SH1164 http://flybase.org/reports/FBgn0065513 gene - - - "l(2)SH1164, l(2)SH2 1164" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004133 blow blown fuse http://flybase.org/reports/FBgn0004133 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with rols mesoderm development ; GO:0007498 | inferred from expression pattern myoblast fusion ; GO:0007520 | traceable author statement myoblast fusion ; GO:0007520 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype podosome ; GO:0002102 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement "CG1363, l(2)43Eb, Blow, blow" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG1363 11-Aug-17 DroID_v2017_08 "Drer\zgc:92360, Drer\adap2" "Scer\GTS1, Scer\AGE2" "Cele\git-1, Cele\F59A2.5" - "Mmus\Adap1, Mmus\Adap2" "Hsap\CA3, Hsap\ADAP2, Hsap\ADAP1" " embryonic stage | stage 11-14 , embryonic stage | stage 10 " " embryonic myoblast

, mesoderm | restricted & segmentally repeated

" embryonic stage | stage 11-14 embryonic myoblast

"lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,viable" "embryonic myoblast,A1-7 dorsal acute muscle 1,myoblast,somatic muscle primordium,embryonic/larval somatic muscle,presumptive embryonic/larval muscle system,fusion competent cell" FBgn0001611 l(1)dd3 lethal (1) discs degenerate 3 http://flybase.org/reports/FBgn0001611 - gene - - - "d.deg.-3, l(1)d deg-3, l(1)d.deg.-3, l(1)d.deg.3, l(1)dd3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,cell lethal,germline clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "cell cycle,imaginal disc,cell autonomous,somatic clone,embryonic/larval brain,embryonic/larval optic lobe,foregut imaginal ring,embryonic/larval salivary gland,gonad,male" FBgn0260016 bha bahia http://flybase.org/reports/FBgn0260016 gene - - - bha - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "chorion,dorsal appendage,chorion | germline clone" FBgn0262888 CR43243 - http://flybase.org/reports/FBgn0262888 non_protein_coding_gene - - - "CG43243, CR43243" - CR43243 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063382 snoRNA:U29:54Ed snoRNA:U29:54Ed http://flybase.org/reports/FBgn0063382 snoRNA_gene - - - "U29snoRNA, CR32895, snoRNA:U29:54Ed, DmSnR71b" - CR32895 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016784 anon-91Ab anon-91Ab http://flybase.org/reports/FBgn0016784 - gene - - - anon-91Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031023 CG14200 - http://flybase.org/reports/FBgn0031023 protein_coding_gene - - - CG14200 IPR000313:PWWP domain CG14200 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262185 mir-995 mir-995 stem loop http://flybase.org/reports/FBgn0262185 miRNA_gene - - - "mir-995, miR-995, miR-20072, 995, CR42892, dme-miR-995" - CR42892 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "eye,male,wing,wing margin,1st posterior cell" FBgn0002062 l(2)40Fg lethal (2) 40Fg http://flybase.org/reports/FBgn0002062 - gene - - - "40Fg, l(2Lh)Fg, GroupVI, l(2L)D', l(2)40Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0262363 CG43061 - http://flybase.org/reports/FBgn0262363 protein_coding_gene molecular_function ; GO:0003674 | no biological data available pathogenesis ; GO:0009405 | inferred from electronic annotation with InterPro:IPR012624 biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR012624 cellular_component ; GO:0005575 | no biological data available CG43061 IPR012624:Conotoxin I-superfamily CG43061 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Clpsl2, Mmus\Clps" "Hsap\CLPSL1, Hsap\CLPS" FBgn0037051 CG10565 - http://flybase.org/reports/FBgn0037051 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 - - CG10565 "IPR001005:SANT/Myb domain, IPR001623:DnaJ domain, IPR009057:Homeobox domain-like, IPR017877:Myb-like domain, IPR032003:Ribosome-associated complex head domain" CG10565 11-Aug-17 DroID_v2017_08 "Drer\vwa9, Drer\dnajc2" Scer\ZUO1 Cele\dnj-11 "Xtro\vwa9, Xtro\dnajc2" "Mmus\Vwa9, Mmus\Dnajc2" "Hsap\DNAJB4, Hsap\DNAJC2" "viable,visible" trichogen cell DRSC11620 I 0.590226745 -2.394098507 0.608748108 0.037200972 -0.255469366 -0.102439536 FBgn0263838 CR43700 - http://flybase.org/reports/FBgn0263838 non_protein_coding_gene - - - CR43700 - CR43700 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038315 CG14866 - http://flybase.org/reports/FBgn0038315 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - CG14866 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG14866 11-Aug-17 DroID_v2017_08 "Drer\LOC101884413, Drer\si:ch73-361h17.1, Drer\si:ch73-111e15.1, Drer\si:dkey-61f9.1, Drer\zmp:0000000924, Drer\si:ch211-232p21.6, Drer\si:ch73-343l4.8, Drer\cd209, Drer\si:ch211-170d8.5, Drer\si:dkey-187i8.2, Drer\si:ch73-86n18.1, Drer\LOC101884526, Drer\si:ch73-343l4.2, Drer\LOC100331140, Drer\illr1, Drer\si:ch211-214k5.3, Drer\zgc:174904, Drer\LOC100007376, Drer\LOC101886537, Drer\si:dkey-61f9.2, Drer\illr3, Drer\si:ch211-133n4.7, Drer\si:ch73-122g19.1, Drer\si:ch211-283g2.3, Drer\illr4, Drer\illr2, Drer\zmp:0000000937" - "Cele\clec-185, Cele\clec-160, Cele\clec-198, Cele\clec-149, Cele\C25G4.17, Cele\clec-78, Cele\clec-184, Cele\clec-202, Cele\clec-199" - "Mmus\Cd209b, Mmus\Clec4a1, Mmus\Clec4b2, Mmus\Mgl2, Mmus\Clec4n, Mmus\Asgr1, Mmus\Cd209d, Mmus\Cd207, Mmus\Cd209e, Mmus\Clec4b1, Mmus\Cd209a, Mmus\Clec4d, Mmus\Clec4a2, Mmus\Asgr2, Mmus\Clec4g, Mmus\Fcer2a, Mmus\Clec4a3, Mmus\Clec10a, Mmus\Clec4e, Mmus\Cd209f, Mmus\Cd209g, Mmus\Clec4f, Mmus\Cd209c, Mmus\Clec4a4" "Hsap\CLEC10A, Hsap\CD207, Hsap\CLEC4M, Hsap\CLEC6A, Hsap\CD209, Hsap\CLEC4E, Hsap\CLEC4A, Hsap\CLEC9A, Hsap\ASGR2, Hsap\CLEC17A, Hsap\CLEC4G, Hsap\CLEC4F, Hsap\CLEC4D, Hsap\CLEC4C, Hsap\ASGR1, Hsap\FCER2" viable FBgn0030995 CG7914 - http://flybase.org/reports/FBgn0030995 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000452136 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001834, InterPro:IPR017927, InterPro:IPR017938" - CG7914 "IPR001834:NADH:cytochrome b5 reductase (CBR), IPR008333:Oxidoreductase, FAD-binding domain, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel" CG7914 11-Aug-17 DroID_v2017_08 "Drer\cyb5r3, Drer\cyb5r1, Drer\cyb5r2, Drer\cyb5r4, Drer\oxnad1" "Scer\CYC2, Scer\AIM33, Scer\MCR1, Scer\PGA3, Scer\CBR1" - "Xtro\cyb5r4, Xtro\cyb5r1, Xtro\oxnad1, Xtro\cyb5r2, Xtro\cyb5r3" "Mmus\Cyb5rl, Mmus\Cyb5r3, Mmus\Cyb5r1, Mmus\Cyb5r4, Mmus\Oxnad1, Mmus\Cyb5r2" "Hsap\CYB5R4, Hsap\CYB5RL, Hsap\OXNAD1, Hsap\CYB5R2, Hsap\CYB5R1, Hsap\CYB5R3" viable FBgn0033558 CG12344 - http://flybase.org/reports/FBgn0033558 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 chloride channel activity ; GO:0005254 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001055382 "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006029, InterPro:IPR006201" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201" "CG12344, Lcch-47C, CT23391" "IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000:Neurotransmitter-gated ion-channel, conserved site" CG12344 11-Aug-17 DroID_v2017_08 "Drer\glra4b, Drer\glrba, Drer\glra1, Drer\glra4a, Drer\glrbb, Drer\glra2, Drer\glra3" - "Cele\lgc-38, Cele\lgc-49, Cele\unc-49" "Xtro\glra2, Xtro\glrb, Xtro\glra1, Xtro\glra3" "Mmus\Glra4, Mmus\Glrb, Mmus\Glra2, Mmus\Glra1, Mmus\Glra3" "Hsap\GLRA4, Hsap\GLRA1, Hsap\GLRA2, Hsap\GLRA3, Hsap\GLRB" "viable,fertile" FBgn0036410 CG8100 - http://flybase.org/reports/FBgn0036410 protein_coding_gene - - - "CG8100, lincRNA.S5087" "IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set, IPR008922:Uncharacterised domain, di-copper centre" CG8100 11-Aug-17 DroID_v2017_08 - - "Cele\C49A9.3, Cele\F58F9.4, Cele\C49A9.2" - - - viable FBgn0035641 CG5568 - http://flybase.org/reports/FBgn0035641 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG5568 "IPR000873:AMP-dependent synthetase/ligase, IPR025110:AMP-binding enzyme C-terminal domain" CG5568 11-Aug-17 DroID_v2017_08 "Drer\acsf3, Drer\acsbg1" Scer\PCS60 "Cele\acs-6, Cele\acs-9, Cele\mec-18, Cele\C25G6.3, Cele\C32E8.6, Cele\acs-10, Cele\acs-7, Cele\acs-14" Xtro\acsf3 "Mmus\Acss2, Mmus\Acsbg1, Mmus\Acsf3" "Hsap\ACSBG1, Hsap\ACSS2, Hsap\ACSF3" lethal FBgn0260246 GSd210 - http://flybase.org/reports/FBgn0260246 gene - - - GSd210 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective" FBgn0028132 l(3)S051022a lethal (3) S051022a http://flybase.org/reports/FBgn0028132 gene - - - "0510/22, l(3)S051022, l(3)S051022a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000396 cv-b crossveinless b http://flybase.org/reports/FBgn0000396 - gene - - - cv-b - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "anterior crossvein,posterior crossvein" FBgn0035558 CG11357 - http://flybase.org/reports/FBgn0035558 protein_coding_gene "galactosyltransferase activity ; GO:0008378 | inferred from electronic annotation with InterPro:IPR002659 transferase activity, transferring glycosyl groups ; GO:0016757 | inferred from sequence or structural similarity with EMBL:Y15062" protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR002659 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "BcDNA:GM04393, CG11357, dbeta3GnT, GalT2" "IPR002659:Glycosyl transferase, family 31" CG11357 11-Aug-17 DroID_v2017_08 "Drer\zgc:194551, Drer\zgc:194330, Drer\b3gnt7, Drer\b3gnt9, Drer\si:dkey-160o24.3, Drer\b3gnt3, Drer\LOC100535930, Drer\si:ch211-126g16.11, Drer\b3gnt2b, Drer\b3gnt2a, Drer\b3galt1a, Drer\b3gnt2l, Drer\b3galt4, Drer\LOC565422, Drer\b3gnt7l, Drer\si:dkey-175m17.6, Drer\zgc:86586, Drer\b3gnt5a, Drer\b3galnt2, Drer\b3gnt5b, Drer\b3galt2, Drer\si:ch211-126g16.10, Drer\b3galt1b" - "Cele\C54C8.3, Cele\T15D6.5, Cele\bus-17, Cele\C47F8.5, Cele\F48F7.3, Cele\T09F5.1, Cele\B0024.15, Cele\bre-2, Cele\C47F8.3, Cele\F14B6.6, Cele\T09E11.10, Cele\B0024.3, Cele\E03H4.11, Cele\F14B6.4, Cele\bre-5, Cele\C47F8.6" "Xtro\LOC100485652, Xtro\b3gnt3, Xtro\b3gnt5, Xtro\b3gnt4, Xtro\b3gnt2, Xtro\LOC100489278, Xtro\LOC100489267, Xtro\b3galt4, Xtro\LOC100494668, Xtro\b3galt1, Xtro\b3galt2, Xtro\LOC100487553, Xtro\LOC101732799, Xtro\b3galnt2, Xtro\LOC100486246, Xtro\LOC100494986, Xtro\LOC100493833, Xtro\b3gnt6, Xtro\b3gnt3" "Mmus\B3gnt6, Mmus\B3galt1, Mmus\B3galnt1, Mmus\B3gnt8, Mmus\B3galt2, Mmus\B3galnt2, Mmus\B3gnt7, Mmus\B3galt5, Mmus\B3gnt2, Mmus\B3gnt3, Mmus\B3gnt5, Mmus\B3gnt9, Mmus\B3galt4, Mmus\B3gnt4" "Hsap\B3GNT5, Hsap\B3GALT5, Hsap\B3GNT2, Hsap\B3GNT4, Hsap\B3GNT9, Hsap\B3GALT1, Hsap\B3GALNT1, Hsap\B3GNT6, Hsap\B3GALT4, Hsap\B3GALT2, Hsap\B3GNT3, Hsap\B3GALNT2, Hsap\B3GNT8, Hsap\B3GNT7" "learning defective,viable,fertile" FBgn0013673 mt:ATPase8 mitochondrial ATPase subunit 8 http://flybase.org/reports/FBgn0013673 FBgn0002867 protein_coding_gene hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from electronic annotation with InterPro:IPR001421 ATP synthesis coupled proton transport ; GO:0015986 | inferred from electronic annotation with InterPro:IPR001421 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from electronic annotation with InterPro:IPR001421" "CG34072, ATPase8, URF6L, mt:ATPase8, ATP8, atp8, Atp8ase" "IPR001421:ATP synthase protein 8, metazoa" CG34072 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013574 l(3)82Fb lethal (3) 82Fb http://flybase.org/reports/FBgn0013574 - gene - - - l(3)82Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" "adult abdomen,adult head" FBgn0002380 l(3)93Bb lethal (3) 93Bb http://flybase.org/reports/FBgn0002380 - gene - - - "er4, l(3)er4, l(3)93Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" wing FBgn0025423 Dl::Nrg Dl::Nrg http://flybase.org/reports/FBgn0025423 - engineered_fusion_gene - - - Dl::Nrg - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing vein L3,wing blade" FBgn0265818 CR44607 - http://flybase.org/reports/FBgn0265818 non_protein_coding_gene - - - "lincRNA.15, CR44607" - CR44607 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037781 Fancl Fancl http://flybase.org/reports/FBgn0037781 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:20748 DNA repair ; GO:0006281 | inferred from mutant phenotype protein monoubiquitination ; GO:0006513 | inferred from mutant phenotype Fanconi anaemia nuclear complex ; GO:0043240 | inferred from electronic annotation with InterPro:IPR026848 cellular_component ; GO:0005575 | no biological data available "FANCL, CG12812, Fancl, FAL" "IPR019162:Fanconi anemia complex, subunit FancL, WD-repeat containing domain, IPR026848:E3 ubiquitin-protein ligase FANCL, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR026850:FANCL C-terminal domain" CG12812 11-Aug-17 DroID_v2017_08 Drer\fancl - "Cele\C09E7.8, Cele\E03H4.2" Xtro\fancl Mmus\Fancl Hsap\FANCL "visible,chemical conditional,chemical sensitive,viable" "eye,chemical conditional" DRSC14550 I -1.698582147 0.119800945 0.642479834 0.614919858 -0.255532089 1.083039591 FBgn0002664 mat(2)ea-A maternal effect early arrest A http://flybase.org/reports/FBgn0002664 - gene - - - "mat(2)earlyPB28, mat(2)ea-A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0031319 CG4896 - http://flybase.org/reports/FBgn0031319 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:9902 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from sequence or structural similarity with HGNC:9902" nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:9902 "cg4896, CG4896" "IPR000467:G-patch domain, IPR000504:RNA recognition motif domain, IPR001876:Zinc finger, RanBP2-type" CG4896 11-Aug-17 DroID_v2017_08 "Drer\rbm10, Drer\rbm5, Drer\LOC567058, Drer\aggf1" - Cele\T08B2.5 "Xtro\aggf1, Xtro\rbm5" "Mmus\Rbm5, Mmus\Rbm6, Mmus\Rbm10, Mmus\Gpatch2" "Hsap\RBM5, Hsap\RBM10, Hsap\RBM6" "viable,fertile" FBgn0065688 l(2)SH0649 lethal (2) SH0649 http://flybase.org/reports/FBgn0065688 gene - - - l(2)SH0649 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043853 scaRNA:MeU5-C46 small Cajal body-specific RNA : MeU5-C46 http://flybase.org/reports/FBgn0043853 snoRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "U85 scaRNA, CG31504, CR32863, snoRNA:MeU5-C46, MeU5-C46(U85), snoRNA:U85, dU85, U85scaRNA, U85, scaRNA:MeU5-C46, chr3R:3298692..3298881" - CR32863 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265429 CG44341 - http://flybase.org/reports/FBgn0265429 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44341 - CG44341 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263891 l(3)F58 - http://flybase.org/reports/FBgn0263891 gene - - - l(3)F58 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0031820 Daxx Daxx-like protein http://flybase.org/reports/FBgn0031820 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with p53 "response to oxidative stress ; GO:0006979 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from genetic interaction with p53" - "CG9537, Daxx, DLP" IPR005012:Daxx protein CG9537 11-Aug-17 DroID_v2017_08 Drer\daxx - - Xtro\daxx Mmus\Daxx Hsap\DAXX "viable,short lived,female fertile,reduced,oxidative stress response defective,lethal,visible,increased cell death" "wing,wing disc" FBgn0263389 CG43441 - http://flybase.org/reports/FBgn0263389 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43441 - CG43441 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083973 dunk disrupted underground network http://flybase.org/reports/FBgn0083973 protein_coding_gene - - - "CG34137, dunk" - CG34137 11-Aug-17 DroID_v2017_08 - - - - - - DRSC36514 K 2.001942348 1.745744674 FBgn0260256 GSd316 - http://flybase.org/reports/FBgn0260256 gene - - - GSd316 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040978 CG7473 - http://flybase.org/reports/FBgn0040978 protein_coding_gene - - - CG7473 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262782 Mdh1 Malate dehydrogenase 1 http://flybase.org/reports/FBgn0262782 protein_coding_gene L-malate dehydrogenase activity ; GO:0030060 | inferred from direct assay carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR015955 NADH metabolic process ; GO:0006734 | inferred from biological aspect of ancestor with PANTHER:PTN000600336 oxaloacetate metabolic process ; GO:0006107 | inferred from biological aspect of ancestor with PANTHER:PTN000600336 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000600336 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000600336 lateral inhibition ; GO:0046331 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001157397 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001157397 peroxisome ; GO:0005777 | inferred from sequence model "CG5362, Mdh-1, MDH, Mdh, Mdh2, cMdh, MDH-1, sMdh, MdhD, Mdh1, CT17038" "IPR001236:Lactate/malate dehydrogenase, N-terminal, IPR001252:Malate dehydrogenase, active site, IPR001557:L-lactate/malate dehydrogenase, IPR010945:Malate dehydrogenase, type 2, IPR011274:Malate dehydrogenase, NAD-dependent, cytosolic, IPR015955:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR016040:NAD(P)-binding domain, IPR022383:Lactate/malate dehydrogenase, C-terminal" CG5362 11-Aug-17 DroID_v2017_08 "Drer\mdh1aa, Drer\mdh1b, Drer\mdh1ab" "Scer\MDH1, Scer\MDH3" Cele\mdh-1 Xtro\mdh1 "Mmus\Mdh1, Mmus\Mdh1b" "Hsap\MDH1B, Hsap\MDH1" FBgn0039099 GILT2 Gamma-interferon-inducible lysosomal thiol reductase 2 http://flybase.org/reports/FBgn0039099 protein_coding_gene "oxidoreductase activity, acting on a sulfur group of donors ; GO:0016667 | inferred from sequence or structural similarity with HGNC:5398 disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence model with Pfam:PF03227" oxidation-reduction process ; GO:0055114 | inferred from sequence or structural similarity with HGNC:5398 oxidation-reduction process ; GO:0055114 | inferred from sequence model with Pfam:PF03227 positive regulation of defense response to bacterium ; GO:1900426 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey120, CG10157, GILT, GILT2" "IPR004911:Gamma interferon inducible lysosomal thiol reductase GILT, IPR012336:Thioredoxin-like fold" CG10157 11-Aug-17 DroID_v2017_08 "Drer\ifi30, Drer\si:dkey-197i20.6" - "Cele\pqn-48, Cele\Y18D10A.2, Cele\R07E5.4, Cele\ZK669.2, Cele\C02D5.2, Cele\ZK669.3, Cele\F37H8.5, Cele\W04A4.3" Xtro\ifi30 Mmus\Ifi30 Hsap\IFI30 "immune response defective,long lived,viable" FBgn0027054 CSN4 COP9 signalosome subunit 4 http://flybase.org/reports/FBgn0027054 FBgn0022061 protein_coding_gene NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with CSN7 NEDD8-specific protease activity ; GO:0019784 | contributes_to inferred from direct assay transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype negative regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032435 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity COP9 signalosome ; GO:0008180 | non-traceable author statement cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000091645 COP9 signalosome ; GO:0008180 | inferred from physical interaction with CSN7 COP9 signalosome ; GO:0008180 | inferred from mutant phenotype COP9 signalosome ; GO:0008180 | traceable author statement COP9 signalosome ; GO:0008180 | inferred from direct assay "CSN4, csn4, Dch4, Csn4, DCH4, Cops4, l(2)k08018, CH4, CG8725" "IPR000717:Proteasome component (PCI) domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain" CG8725 11-Aug-17 DroID_v2017_08 Drer\cops4 - Cele\csn-4 Xtro\cops4 Mmus\Cops4 Hsap\COPS4 "lethal,recessive,viable,fertile,female sterile germline-dependent,germline clone,small body,female sterile,chemical sensitive,visible,somatic clone,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during pupal stage" "ovary,germline clone,female germline stem cell,fusome | germline clone,photoreceptor cell,cephalopharyngeal skeleton,trichogen cell,somatic clone,supernumerary,chaeta,mesothoracic tergum" DRSC07350 K 0.884105131 0.660767784 0.84540905 0.454594417 2.89593059 2.872183253 FBgn0025869 C31 C31 http://flybase.org/reports/FBgn0025869 - gene - adult walking behavior ; GO:0007628 | non-traceable author statement - C31 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035909 ergic53 ergic53 http://flybase.org/reports/FBgn0035909 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005052 endomembrane system ; GO:0012505 | inferred from direct assay "l(3)S1760, dergic53, CG6822, dERGIC53, rhea, l(3)s1760, ergic53, ERGIC53" "IPR005052:Legume-like lectin, IPR013320:Concanavalin A-like lectin/glucanase domain" CG6822 11-Aug-17 DroID_v2017_08 Drer\lman1 "Scer\EMP46, Scer\EMP47" Cele\ile-1 "Xtro\lman1, Xtro\cplx3" "Mmus\Lman1, Mmus\Lman1l" "Hsap\LMAN1, Hsap\LMAN1L" "viable,fertile,partially lethal - majority die" FBgn0065132 l(3)SH129 lethal (3) SH129 http://flybase.org/reports/FBgn0065132 gene - - - "l(3)SH129, l(2)SH3 129" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065729 l(2)SH0556 lethal (2) SH0556 http://flybase.org/reports/FBgn0065729 gene - - - l(2)SH0556 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267904 CG46192 - http://flybase.org/reports/FBgn0267904 protein_coding_gene - sperm chromatin condensation ; GO:0035092 | inferred from electronic annotation with InterPro:IPR024460 - CG46192 IPR024460:Protamine-like CG46192 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065742 l(2)SH0523 lethal (2) SH0523 http://flybase.org/reports/FBgn0065742 gene - - - "l(2)SH0523, l(2)SH2 0523" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060848 l(3)S048619a lethal (3) S048619a http://flybase.org/reports/FBgn0060848 gene - - - "0486/19, l(3)S048619a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005013 dipp-4 defective in phototaxis plasticity 4 http://flybase.org/reports/FBgn0005013 - gene - - - dipp-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,visual behavior defective,phototaxis defective" photoreceptor FBgn0028174 l(3)S026420 lethal (3) S026420 http://flybase.org/reports/FBgn0028174 gene - - - "0264/20, l(3)S026420" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0262723 in::mwh - http://flybase.org/reports/FBgn0262723 engineered_fusion_gene - - - in::mwh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020364 anon-17Aa anon-17Aa http://flybase.org/reports/FBgn0020364 - gene - - - "1D10, anon-17Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024141 Bip-p150 Bcd interacting protein p150 http://flybase.org/reports/FBgn0024141 - gene - - - "p150, Bip-p150" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067104 G5.A G5.A http://flybase.org/reports/FBgn0067104 gene - - - "G5, G5.A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" chaeta FBgn0043984 Su(rst)E304 Su(rst)E304 http://flybase.org/reports/FBgn0043984 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E304, Su(rst)E304" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013499 l(1)LB5 lethal (1) LB5 http://flybase.org/reports/FBgn0013499 - gene - - - "LB5, l(1)LB5" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265652 CR44459 - http://flybase.org/reports/FBgn0265652 non_protein_coding_gene - - - "lincRNA.316, CR44459" - CR44459 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041769 anon-d35 anon-d35 http://flybase.org/reports/FBgn0041769 gene - - - "d35, anon-d35" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032127 CG13114 - http://flybase.org/reports/FBgn0032127 protein_coding_gene - - chorion ; GO:0042600 | inferred from direct assay CG13114 IPR031806:Protein of unknown function DUF4744 CG13114 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0044399 Scim28 Sensitized chromosome inheritance modifier 28 http://flybase.org/reports/FBgn0044399 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0266820 CR45282 - http://flybase.org/reports/FBgn0266820 non_protein_coding_gene - - - CR45282 - CR45282 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045497 Gr22e Gustatory receptor 22e http://flybase.org/reports/FBgn0045497 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr2940.1, CG31936, Gr22e, GR22e" IPR013604:7TM chemoreceptor CG31936 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable DRSC20912 IE 1.536077611 0.764820933 -4.568871423 1.353590474 -0.063108385 0.452981509 FBgn0259666 B0729 - http://flybase.org/reports/FBgn0259666 gene - - - B0729 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0267489 PRY polycystine-related-Y http://flybase.org/reports/FBgn0267489 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000203 cellular_component ; GO:0005575 | no biological data available "CG40930, PRY, CG41367, CG42619, CG45787" "IPR000203:GPS motif, IPR001024:PLAT/LH2 domain, IPR002859:PKD/REJ-like domain" CG45787 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031632 CG15628 - http://flybase.org/reports/FBgn0031632 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 - - "anon-WO02059370.23, CG15628" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG15628 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-76k16.6, Drer\si:dkey-76k16.5, Drer\si:ch73-106k19.2" - Cele\ZK185.3 - - Hsap\GLYATL3 "viable,fertile,body color defective" mesothoracic tergum DRSC00256 K 0.266786191 1.84930585 FBgn0026080 Tip60 Tat interactive protein 60kDa http://flybase.org/reports/FBgn0026080 - protein_coding_gene histone acetyltransferase activity ; GO:0004402 | inferred from mutant phenotype histone acetyltransferase activity ; GO:0004402 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002717 regulation of synaptic plasticity ; GO:0048167 | inferred from direct assay histone H4 acetylation ; GO:0043967 | inferred from mutant phenotype histone exchange ; GO:0043486 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from direct assay nervous system development ; GO:0007399 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from direct assay" polytene chromosome interband ; GO:0005705 | inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont "CG6121, dTip60, dmHAG405, EG0007.7, DmEG0007.7, EG:EG0007.7, Tip60, dTIP60, Dmel/TIP60, Dmel\TIP60, 6121, TIP60, TIP-60" "IPR000953:Chromo/chromo shadow domain, IPR002717:Histone acetyltransferase domain, MYST-type, IPR016181:Acyl-CoA N-acyltransferase, IPR016197:Chromo domain-like, IPR025995:RNA binding activity-knot of a chromodomain" CG6121 11-Aug-17 DroID_v2017_08 "Drer\kat8, Drer\kat5b, Drer\kat7a, Drer\kat7b, Drer\kat6a, Drer\kat6b, Drer\kat5a" "Scer\SAS2, Scer\SAS3, Scer\ESA1" "Cele\mys-2, Cele\mys-1, Cele\lsy-12, Cele\mys-4" "Xtro\kat5, Xtro\kat7, Xtro\kat8, Xtro\trim69.1, Xtro\xnf7" "Mmus\Kat6b, Mmus\Kat5, Mmus\Kat8, Mmus\Kat7, Mmus\Kat6a" "Hsap\KAT5, Hsap\KAT8, Hsap\KAT6A, Hsap\KAT7, Hsap\KAT6B" "locomotor behavior defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,majority die during third instar larval stage,increased mortality during development,partially lethal - majority die,increased cell death,viable,heat sensitive,visible,fertile,partially,cytokinesis defective,cell lethal" "terminal bouton,type I bouton,ectopic,type Ib terminal bouton | ectopic,terminal boutonMef2.247,type Ib terminal bouton | ectopicMef2.247,type Is terminal boutonMef2.247,embryonic/larval brain | third instar larval stage,wing,wing vein,wing disc,trichogen cell" DRSC18661 E -0.55123146 -0.745855978 2.891373343 -2.462615533 0.773167995 -0.238591028 FBgn0083286 E(smoDN)2117 Enhancer of smoDN 2117 http://flybase.org/reports/FBgn0083286 gene - - - E(smoDN)2117 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001794 l(1)Mb26 lethal (1) Mb26 http://flybase.org/reports/FBgn0001794 - gene - - - l(1)Mb26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0261707 CR42743 - http://flybase.org/reports/FBgn0261707 non_protein_coding_gene - - - CR42743 - CR42743 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032595 CG17996 - http://flybase.org/reports/FBgn0032595 protein_coding_gene copper ion binding ; GO:0005507 | inferred from sequence or structural similarity with SGD:S000001620 mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from sequence or structural similarity with SGD:S000001620 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001884832 mitochondrial intermembrane space ; GO:0005758 | inferred from sequence or structural similarity with SGD:S000001620 "BcDNA:GM20557, CG17996" IPR013892:Cytochrome c oxidase biogenesis protein Cmc1-like CG17996 11-Aug-17 DroID_v2017_08 Drer\cmc1 Scer\CMC1 Cele\F01F1.2 Xtro\cmc1 Mmus\Cmc1 Hsap\CMC1 FBgn0052268 Drsl6 Drosomycin-like 6 http://flybase.org/reports/FBgn0052268 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro6, CG11520, Dro-I, CG10815, CG32268, Drs-lI, Drsl6, dro6" "IPR003614:Knottin, scorpion toxin-like" CG32268 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267378 sau sauron http://flybase.org/reports/FBgn0267378 protein_coding_gene phosphatidylinositol-4-phosphate binding ; GO:0070273 | inferred from direct assay phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from direct assay Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab5 inferred from physical interaction with Rab11 phosphatidic acid binding ; GO:0070300 | inferred from direct assay phosphatidylinositol-4-phosphate binding ; GO:0070273 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 phosphatidylinositol-5-phosphate binding ; GO:0010314 | inferred from direct assay "male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype Golgi vesicle budding ; GO:0048194 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 spindle assembly involved in male meiosis ; GO:0007053 | inferred from mutant phenotype retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype retrograde transport, vesicle recycling within Golgi ; GO:0000301 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype cleavage furrow formation ; GO:0036089 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype Golgi to plasma membrane protein transport ; GO:0043001 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype" Golgi apparatus ; GO:0005794 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 Golgi cisterna ; GO:0031985 | inferred from sequence or structural similarity with UniProtKB:Q9H4A6 cleavage furrow ; GO:0032154 | inferred from direct assay Golgi cisterna ; GO:0031985 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 "GOLPH3, sau, CG7085, l(2)s5379, rti, BEST:LD28579, BcDNA:LD10657, Rotini" IPR008628:Golgi phosphoprotein 3-like CG7085 11-Aug-17 DroID_v2017_08 "Drer\golph3l, Drer\golph3, Drer\si:dkey-27b3.2" Scer\VPS74 Cele\Y47G6A.18 "Xtro\golph3, Xtro\golph3l" "Mmus\Golph3l, Mmus\Golph3" "Hsap\GOLPH3, Hsap\GOLPH3L" DRSC00694 I 0.424452961 1.969527731 0.931347088 0.324340516 -0.114453286 0.197195454 FBgn0035401 CG1291 - http://flybase.org/reports/FBgn0035401 protein_coding_gene "alpha-1,3-mannosyltransferase activity ; GO:0000033 | inferred from biological aspect of ancestor with PANTHER:PTN000282458" oligosaccharide-lipid intermediate biosynthetic process ; GO:0006490 | inferred from biological aspect of ancestor with PANTHER:PTN001394375 protein glycosylation in endoplasmic reticulum ; GO:0033577 | inferred from biological aspect of ancestor with PANTHER:PTN001394375 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN001394375 lipid particle ; GO:0005811 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG1291, Alg2, dAlg2" "IPR001296:Glycosyl transferase, family 1, IPR028098:Glycosyltransferase subfamily 4-like, N-terminal domain" CG1291 11-Aug-17 DroID_v2017_08 Drer\alg2 Scer\ALG2 "Cele\algn-2, Cele\bus-8" Xtro\alg2 Mmus\Alg2 Hsap\ALG2 "lethal,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval brain FBgn0034693 CG11073 - http://flybase.org/reports/FBgn0034693 protein_coding_gene - - - CG11073 - CG11073 11-Aug-17 DroID_v2017_08 - - - Xtro\map4 - - "viable,fertile" DRSC04087 K 0.032397861 0.606218717 0.834528238 0.087522026 0.469254622 1.876953573 FBgn0002242 l(3)68Cd lethal (3) 68Cd http://flybase.org/reports/FBgn0002242 - gene - - - "rsg3, l(3)rsg3, l(3)Bl[D], l(3)68Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032445 CG6153 - http://flybase.org/reports/FBgn0032445 protein_coding_gene - cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000256298 "CG6153, 6153" "IPR010400:PITH domain, IPR008979:Galactose-binding domain-like" CG6153 11-Aug-17 DroID_v2017_08 Drer\pithd1 - Cele\ZK353.9 Xtro\pithd1 Mmus\Pithd1 Hsap\PITHD1 viable FBgn0012011 tRNA:Val-AAC-1-1 transfer RNA:Valine-AAC 1-1 http://flybase.org/reports/FBgn0012011 "FBgn0012007, FBgn0051587, FBgn0060030" tRNA_gene GUU codon-amino acid adaptor activity ; GO:0033449 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033449 cytosol ; GO:0005829 | inferred by curator from GO:0033449 "valine tRNA, tRNA-Val-4, val-tRNA-4, tRNA[Val][[4]], AE002708.trna7-ValAAC, tRNA:V4, tRNA:V:AAC:AE002708-a, CR31587, tRNA:val4:89BC, tRNA[Val-AAC], chr3R.trna13-ValAAC, tRNA:Val-AAC-1-1, tRNA:V4:89BC, tRNA-Val-AAC-1-1, GUU" - CR31587 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266650 CR45157 - http://flybase.org/reports/FBgn0266650 non_protein_coding_gene - - - CR45157 - CR45157 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086025 snoRNA:Me28S-A2589c - http://flybase.org/reports/FBgn0086025 snoRNA_gene - - - "snoRNA:Me28S-A2589c, Me28S-Am2589c, CR34654, chr2R:16839179..16839292" - CR34654 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003229 ref(1)H refractory to sigma H http://flybase.org/reports/FBgn0003229 - gene - - - "Ref(1)H, ref(1)H" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000951 Fs(2)Bil Female sterile (2) Billa http://flybase.org/reports/FBgn0000951 - gene - - - "Billa, Fs(2)Sz2, Fs(2)Bil" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,dominant" "dorsal appendage,egg" FBgn0029759 CG12732 - http://flybase.org/reports/FBgn0029759 protein_coding_gene - - - CG12732 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267127 CR45567 - http://flybase.org/reports/FBgn0267127 non_protein_coding_gene - - - CR45567 - CR45567 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261514 NimA Nimrod A http://flybase.org/reports/FBgn0261514 protein_coding_gene molecular_function ; GO:0003674 | no biological data available phagocytosis ; GO:0006909 | inferred from sequence or structural similarity with drpr negative regulation of Notch signaling pathway ; GO:0045746 | inferred from biological aspect of ancestor with PANTHER:PTN001170207 integral component of membrane ; GO:0016021 | inferred from sequence model "CG31765, j, CT25428, CG8855, BG:DS00180.5, DS00180.5, CG31841, CG42282, NimA, nimA" "IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site, IPR011489:EMI domain" CG42282 11-Aug-17 DroID_v2017_08 "Drer\megf11, Drer\dkk1a, Drer\megf6a, Drer\dkk2, Drer\scarf1, Drer\zgc:158328, Drer\pear1, Drer\LOC101883341, Drer\megf10, Drer\esm1, Drer\tnfaip6, Drer\ccbe1, Drer\megf6b" - Cele\Y64G10A.7 "Xtro\tnfaip6, Xtro\megf11, Xtro\stab2" "Mmus\Tnfaip6, Mmus\Esm1, Mmus\Pear1, Mmus\Stab1, Mmus\Scarf1, Mmus\Dkk2, Mmus\Megf11, Mmus\Megf10, Mmus\Egfem1, Mmus\Megf6, Mmus\Dkk3, Mmus\Dlk1" "Hsap\SCARF2, Hsap\DKK2, Hsap\PEAR1, Hsap\MEGF6, Hsap\TIE1, Hsap\MEGF11, Hsap\DLK1, Hsap\SCARF1, Hsap\TNFAIP6, Hsap\MEGF10" FBgn0063499 GstE10 Glutathione S transferase E10 http://flybase.org/reports/FBgn0063499 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG17522, DmGSTE10, GstE10, GSTE10, gste10" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17522 11-Aug-17 DroID_v2017_08 "Drer\gstt1b, Drer\gstt1a, Drer\mars, Drer\eef1e1, Drer\gstr, Drer\eef1g, Drer\gstt2, Drer\vars" "Scer\CAM1, Scer\YGR201C, Scer\GTT2, Scer\URE2, Scer\TEF4, Scer\GTT1" "Cele\gst-21, Cele\gst-29" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Gstt4, Mmus\Eef1e1, Mmus\Eef1g, Mmus\Gstt3, Mmus\Mars, Mmus\Gstt2, Mmus\Vars, Mmus\Gstt1" "Hsap\EEF1E1, Hsap\GSTT1, Hsap\GSTT2, Hsap\EEF1G, Hsap\MARS, Hsap\GSTT2B, Hsap\VARS" viable FBgn0039004 Nup133 Nucleoporin 133kD http://flybase.org/reports/FBgn0039004 protein_coding_gene nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with HGNC:18016 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 "chromatin organization ; GO:0006325 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 SMAD protein import into nucleus ; GO:0007184 | NOT inferred from mutant phenotype nuclear pore distribution ; GO:0031081 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery ; GO:0000972 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 mRNA export from nucleus ; GO:0006406 | inferred from sequence or structural similarity with HGNC:18016" condensed chromosome kinetochore ; GO:0000777 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN000334066 nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with HGNC:18016 nuclear pore outer ring ; GO:0031080 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 "Nup133, CG6958, nup133, Nup 133" "IPR007187:Nucleoporin, Nup133/Nup155-like, C-terminal, IPR015943:WD40/YVTN repeat-like-containing domain, IPR014908:Nucleoporin, Nup133/Nup155-like, N-terminal" CG6958 11-Aug-17 DroID_v2017_08 Drer\nup133 Scer\NUP133 Cele\npp-15 Xtro\nup133 Mmus\Nup133 Hsap\NUP133 FBgn0082619 S(CycE[JP])59S18 S(CycE[JP])59S18 http://flybase.org/reports/FBgn0082619 gene - - - "59S18, S(CycE[JP])59S18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263109 CG43366 - http://flybase.org/reports/FBgn0263109 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG43366, CG12551, CG14470" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG43366 11-Aug-17 DroID_v2017_08 "Drer\zgc:174260, Drer\serpina7, Drer\si:ch211-186e20.7, Drer\zgc:174259, Drer\serpina1, Drer\serpina1l" - - - "Mmus\Serpina3j, Mmus\Serpina3k, Mmus\Serpina3i, Mmus\Serpina3b, Mmus\Serpina11, Mmus\Serpina9, Mmus\Serpina1e, Mmus\Serpina6, Mmus\Serpina1a, Mmus\Serpina3a, Mmus\Serpina1c, Mmus\Serpina1d, Mmus\Serpina3c, Mmus\Serpina16, Mmus\Serpina5, Mmus\Serpina3f, Mmus\Serpina7, Mmus\Serpina3n, Mmus\Serpina3g, Mmus\Serpina12, Mmus\Serpina3m, Mmus\Serpina1f, Mmus\Serpina1b" "Hsap\SERPINA5, Hsap\SERPINA2, Hsap\SERPINA9, Hsap\SERPINA7, Hsap\SERPINA11, Hsap\SERPINA3, Hsap\SERPINA1, Hsap\SERPINA4, Hsap\SERPINA12, Hsap\SERPINA6" DRSC25725 K -0.397217175 0.111318732 0.936519971 0.637256728 1.893891475 -0.476813472 FBgn0259360 EP-614 - http://flybase.org/reports/FBgn0259360 gene - - - EP-614 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0051816 CG31816 - http://flybase.org/reports/FBgn0051816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs19f07, NEST:bs34h07, NEST:bs11b11, CG31816" - CG31816 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC01547 I -0.357568355 -1.569204021 -0.36647446 0.419010155 0.299510954 0.072152828 FBgn0016807 l(1)K9 lethal (1) K9 http://flybase.org/reports/FBgn0016807 - gene - - - "l(1)K9, K9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023140 WppC White prepupal locus C http://flybase.org/reports/FBgn0023140 - gene - - - "6, 3, 12, WppC" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263617 CR43626 - http://flybase.org/reports/FBgn0263617 non_protein_coding_gene - - - CR43626 - CR43626 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060847 l(3)S048716b lethal (3) S048716b http://flybase.org/reports/FBgn0060847 gene - - - "0487/16, l(3)S048716b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025746 l(3)99Fa lethal (3) 99Fa http://flybase.org/reports/FBgn0025746 - gene - - - l(3)99Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" FBgn0026222 l(3)03608 lethal (3) 03608 http://flybase.org/reports/FBgn0026222 - gene - - - l(3)03608 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029523 CR18275 - http://flybase.org/reports/FBgn0029523 pseudogene_attribute - - - "CR18275, CG18275" - CR18275 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die" FBgn0043980 Su(rst)J45 Su(rst)J45 http://flybase.org/reports/FBgn0043980 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "J45, Su(rst)J45" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0008646 E5 E5 http://flybase.org/reports/FBgn0008646 FBgn0038187 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG9930, E5" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG9930 11-Aug-17 DroID_v2017_08 "Drer\vax2, Drer\emx2, Drer\emx1, Drer\vax1, Drer\noto, Drer\emx3" - "Cele\ceh-23, Cele\ceh-2, Cele\ceh-99" "Xtro\emx2, Xtro\emx1.2, Xtro\not, Xtro\vax1" "Mmus\Emx1, Mmus\Vax2, Mmus\Noto, Mmus\Emx2, Mmus\Vax1" "Hsap\HOXA13, Hsap\VAX2, Hsap\NOTO, Hsap\EMX2, Hsap\VAX1, Hsap\EMX1, Hsap\NKX1-1" viable FBgn0033603 Cpr47Ef Cuticular protein 47Ef http://flybase.org/reports/FBgn0033603 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr47Ef, CG13214, DmelCpr47Ef" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG13214 11-Aug-17 DroID_v2017_08 "Drer\zgc:113232, Drer\LOC100003040, Drer\LOC100537277" - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" Xtro\col9a3 "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0032843 CG10730 - http://flybase.org/reports/FBgn0032843 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular space ; GO:0005615 | inferred from direct assay "38B.7, CG10730, gi21430366, gi7298655" "IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain" CG10730 11-Aug-17 DroID_v2017_08 - - "Cele\Y38A10A.2, Cele\Y41E3.1, Cele\R03G8.1, Cele\Y73F8A.35, Cele\R03G8.3, Cele\T07G12.3, Cele\M03F8.5, Cele\F10C2.3, Cele\F15H10.7, Cele\F07C3.3, Cele\K03A11.4, Cele\F32G8.2, Cele\T23E1.1, Cele\F32D8.2" - - - viable FBgn0000458 dis distorted eye http://flybase.org/reports/FBgn0000458 - gene - - - dis - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,macrochaeta,wing,wing vein" FBgn0039071 bb8 big bubble 8 http://flybase.org/reports/FBgn0039071 protein_coding_gene glutamate dehydrogenase (NAD+) activity ; GO:0004352 | inferred from electronic annotation with InterPro:IPR033922 glutamate dehydrogenase [NAD(P)+] activity ; GO:0004353 | inferred from sequence or structural similarity with UniProt:P49448 inferred from sequence or structural similarity with UniProtKB:P00367 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006095, InterPro:IPR006096, InterPro:IPR006097, InterPro:IPR014362 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR006095, InterPro:IPR006096, InterPro:IPR006097 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype glutamate catabolic process to 2-oxoglutarate ; GO:0019551 | inferred from sequence or structural similarity with UniProt:P49448 inferred from sequence or structural similarity with UniProtKB:P00367 spermatogenesis ; GO:0007283 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProt:P49448 inferred from sequence or structural similarity with UniProtKB:P00367 "CG4434, bb8" "IPR006095:Glutamate/phenylalanine/leucine/valine dehydrogenase, IPR006096:Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal, IPR006097:Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain, IPR014362:Glutamate dehydrogenase, IPR016040:NAD(P)-binding domain, IPR033922:NAD(P) binding domain of glutamate dehydrogenase, IPR033524:Leu/Phe/Val dehydrogenases active site" CG4434 11-Aug-17 DroID_v2017_08 "Drer\glud1b, Drer\glud1a" "Scer\GDH1, Scer\GDH3" Cele\gdh-1 Xtro\glud1 Mmus\Glud1 "Hsap\GLUD1, Hsap\GLUD2" viable FBgn0266405 CR45045 - http://flybase.org/reports/FBgn0266405 non_protein_coding_gene - - - CR45045 - CR45045 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027646 l(2)k09017a lethal (2) k09017a http://flybase.org/reports/FBgn0027646 - gene - - - l(2)k09017a - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029696 CG15571 - http://flybase.org/reports/FBgn0029696 protein_coding_gene molecular_function ; GO:0003674 | no biological data available eggshell chorion assembly ; GO:0007306 | inferred from expression pattern inferred from genomic context chorion ; GO:0042600 | inferred from genomic context CG15571 - CG15571 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011153 l(1)Q231 lethal (1) Q231 http://flybase.org/reports/FBgn0011153 FBgn0010210 gene - - - l(1)Q231 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0084515 S16.6 S16.6 http://flybase.org/reports/FBgn0084515 gene - - - S16.6 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0069202 l(2)46Fb lethal (2) 46Fb http://flybase.org/reports/FBgn0069202 gene - - - "6.6, 15.4, 10.5, B, l(2)46CFl, l(2)46CFg, l(2)46Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,semidominant" FBgn0001878 l(1)YD23a lethal (1) YD23a http://flybase.org/reports/FBgn0001878 - gene - - - "l(1)YD23, l(1)YD23a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266514 s-535 - http://flybase.org/reports/FBgn0266514 gene - - - s-535 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027651 l(2)44A lethal (2) 44A http://flybase.org/reports/FBgn0027651 - gene - - - l(2)44A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263316 Mrp4 Multidrug resistance protein 4 http://flybase.org/reports/FBgn0263316 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap response to hypoxia ; GO:0001666 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 response to anoxia ; GO:0034059 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "Mrp4, CG14709, dMRP4, Dme_CG14709, CK01227, BEST:CK01227, BEST:CK02472, EP3221" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site" CG14709 11-Aug-17 DroID_v2017_08 "Drer\abcc4, Drer\abcc6b.2, Drer\abcc3, Drer\abcc1, Drer\abcc5, Drer\abcc13, Drer\abcc12, Drer\abcc9, Drer\abcc8, Drer\abcc2, Drer\abcc6a, Drer\abcc10, Drer\cftr, Drer\LOC100329706" "Scer\NFT1, Scer\STE6, Scer\VMR1, Scer\BPT1, Scer\YKR104W, Scer\YCF1, Scer\YBT1, Scer\YOR1" "Cele\mrp-7, Cele\mrp-2, Cele\mrp-8, Cele\mrp-3, Cele\mrp-5, Cele\mrp-1, Cele\mrp-6, Cele\mrp-4" "Xtro\abcc1, Xtro\abcc4, Xtro\abcc10, Xtro\abcc3, Xtro\abcc6, Xtro\cftr" "Mmus\Abcc12, Mmus\Cftr, Mmus\Abcc9, Mmus\Abcc3, Mmus\Abcc5, Mmus\Abcc2, Mmus\Abcc8, Mmus\Abcc10, Mmus\Abcc1, Mmus\Abcc6, Mmus\Abcc4" "Hsap\ABCC1, Hsap\ABCC6, Hsap\ABCC12, Hsap\ABCC3, Hsap\ABCC5, Hsap\CFTR, Hsap\ABCC4, Hsap\ABCC9, Hsap\ABCC10, Hsap\ABCC8, Hsap\ABCC2, Hsap\ABCC11" FBgn0001162 gustM gustatory-defective M http://flybase.org/reports/FBgn0001162 - gene - - - gustM - - 11-Aug-17 DroID_v2017_08 - - - - - - taste perception defective FBgn0067775 fragile-locus-A fragile locus A http://flybase.org/reports/FBgn0067775 gene molecular_function ; GO:0003674 | no biological data available egg activation ; GO:0007343 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fragile-locus-A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" FBgn0002454 mdm many discs missing http://flybase.org/reports/FBgn0002454 FBgn0011654 gene - - - "l(3)J16, l(3)SG7, mdm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "some die during larval stage,lethal - all die before end of larval stage,recessive" imaginal disc FBgn0267677 CR46013 - http://flybase.org/reports/FBgn0267677 non_protein_coding_gene - - - CR46013 - CR46013 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013690 mt:tRNA:Cys-GCA mitochondrial transfer RNA:Cysteine-GCA http://flybase.org/reports/FBgn0013690 FBgn0002867 tRNA_gene - - - "CR34065, tRNAcys, tRNA[Cys], tRNA-Cys, mtdbD00006296, mt:tRNA:Cys-GCA, mt:tRNA:C" - CR34065 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058112 CG40112 - http://flybase.org/reports/FBgn0058112 protein_coding_gene - - - CG40112 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265933 CR44722 - http://flybase.org/reports/FBgn0265933 non_protein_coding_gene - - - "CR44722, lincRNA.508" - CR44722 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000366 cr-3 cream 3 http://flybase.org/reports/FBgn0000366 - gene - - - cr-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,recessive" "Malpighian tubule,pigment cell" FBgn0038820 CG4000 - http://flybase.org/reports/FBgn0038820 protein_coding_gene - - - CG4000 - CG4000 11-Aug-17 DroID_v2017_08 Drer\col12a1a - "Cele\col-144, Cele\col-10, Cele\col-107, Cele\col-91" - - - "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0020305 dbe dribble http://flybase.org/reports/FBgn0020305 "FBgn0022118, FBgn0022171, FBgn0024894" protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000286619 rRNA processing ; GO:0006364 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000286619 nucleoplasm ; GO:0005654 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "l(2)k06708, l(2)k05428, CG4258, dbe, DBE, dribble" "IPR004087:K Homology domain, IPR024166:Ribosomal RNA assembly KRR1, IPR004088:K Homology domain, type 1" CG4258 11-Aug-17 DroID_v2017_08 Drer\krr1 "Scer\PNO1, Scer\KRR1" Cele\C05C8.2 Xtro\krr1 Mmus\Krr1 Hsap\KRR1 "lethal,recessive,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "ovariole,germline clone,mesothoracic tergum" FBgn0087002 apolpp apolipophorin http://flybase.org/reports/FBgn0087002 protein_coding_gene heme binding ; GO:0020037 | inferred from direct assay lipid transporter activity ; GO:0005319 | inferred from direct assay fatty acid binding ; GO:0005504 | inferred from direct assay receptor binding ; GO:0005102 | inferred from physical interaction with ptc microtubule binding ; GO:0008017 | inferred from direct assay lipid transporter activity ; GO:0005319 | inferred from mutant phenotype retinol binding ; GO:0019841 | inferred from direct assay lipid transport ; GO:0006869 | inferred from direct assay Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype transport ; GO:0006810 | traceable author statement lipid transport ; GO:0006869 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay endocytic vesicle ; GO:0030139 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement lipid particle ; GO:0005811 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay "RfaBp, RFABG, CG11064, ApoLII, ApoLI, T3, RfaBP, RFBP, DRBP, lipophorin, Lipophorin, Rfabg, Lpp, RFABP, rfabg, ApoL1, ApoL2, Rfabp, apolpp, apoLpp, chr4:1088013..1088173, apoLI, apoLII, apoLPP" "IPR015817:Vitellinogen, open beta-sheet, subdomain 1, IPR015819:Lipid transport protein, beta-sheet shell, IPR001747:Lipid transport protein, N-terminal, IPR001846:von Willebrand factor, type D domain, IPR009454:Lipid transport, open beta-sheet, IPR011030:Vitellinogen, superhelical, IPR015255:Vitellinogen, open beta-sheet, IPR015816:Vitellinogen, beta-sheet N-terminal" CG11064 11-Aug-17 DroID_v2017_08 "Drer\apobb.1, Drer\si:dkey-4c23.3, Drer\vtg1, Drer\vtg2, Drer\vtg6, Drer\vtg3, Drer\vtg4, Drer\apoba, Drer\vtg7" - "Cele\vit-2, Cele\vit-1" "Xtro\vtga2, Xtro\LOC100485054" Mmus\Apob "Hsap\APOB, Hsap\LOC400499" FBgn0263234 Phae1 Phaedra 1 http://flybase.org/reports/FBgn0263234 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "CG16996, Phae1, SP134" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG16996 11-Aug-17 DroID_v2017_08 Drer\zmp:0000001088 - Cele\svh-1 - "Mmus\Klk1b3, Mmus\Prss53, Mmus\Prss36" "Hsap\PRSS36, Hsap\PRSS53" FBgn0266634 CR45141 - http://flybase.org/reports/FBgn0266634 non_protein_coding_gene - - - CR45141 - CR45141 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067861 Sdic1 Sperm-specific dynein intermediate chain 1 http://flybase.org/reports/FBgn0067861 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 sperm flagellum ; GO:0036126 | inferred from direct assay "CG9580, Sdic1, Sdic:CG9580" "IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2" CG9580 11-Aug-17 DroID_v2017_08 "Drer\dync1i2b, Drer\LOC103908626, Drer\dync1i1, Drer\dnai1.1, Drer\dnai2a" "Scer\PFS2, Scer\PAC11" "Cele\dyci-1, Cele\prp-17" "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Dync1i1, Mmus\Dync1i2, Mmus\Wdr63" "Hsap\DYNC1I1, Hsap\WDR60, Hsap\DYNC1I2" FBgn0265682 CR44489 - http://flybase.org/reports/FBgn0265682 non_protein_coding_gene - - - "lincRNA.183, CR44489" - CR44489 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044385 Scim9 Sensitized chromosome inheritance modifier 9 http://flybase.org/reports/FBgn0044385 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype - Scim9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant,partially lethal - majority die,recessive,mitotic cell cycle defective" "mitosis & nuclear chromosome,nuclear chromosome" FBgn0266911 CR45371 - http://flybase.org/reports/FBgn0266911 non_protein_coding_gene - - - CR45371 - CR45371 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001433 l(1)air7 lethal aberrant immune response 7 http://flybase.org/reports/FBgn0001433 - gene - - - "air7, l(1)air[7], l(1)jnR3, RC61, jnR3, l(1)7Ac, l(1)air7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,cell lethal,germline clone" FBgn0030186 CG2962 - http://flybase.org/reports/FBgn0030186 protein_coding_gene - - - CG2962 IPR031903:Domain of unknown function DUF4766 CG2962 11-Aug-17 DroID_v2017_08 Drer\pou2af1 - - - Mmus\Pou2af1 Hsap\POU2AF1 viable FBgn0011199 l(1)304-69 lethal (1) 304-69 http://flybase.org/reports/FBgn0011199 FBgn0010203 gene - - - "304-69, l(1)304-69" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051721 Trim9 Tripartite motif containing 9 http://flybase.org/reports/FBgn0051721 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:16288 zinc ion binding ; GO:0008270 | inferred from sequence model" axonogenesis ; GO:0007409 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with HGNC:16288 netrin-activated signaling pathway ; GO:0038007 | inferred from genetic interaction with fra inferred from physical interaction with fra inferred from physical interaction with pico axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype "intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR003649 cellular_component ; GO:0005575 | no biological data available" "CG31721, CG6256, CG13145, Trim9, Asap, asap, dTrim9" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR000315:B-box-type zinc finger, IPR001841:Zinc finger, RING-type, IPR001870:B30.2/SPRY domain, IPR003649:B-box, C-terminal, IPR003877:SPRY domain, IPR003961:Fibronectin type III, IPR017903:COS domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013783:Immunoglobulin-like fold" CG31721 11-Aug-17 DroID_v2017_08 "Drer\btr06, Drer\trim35-24, Drer\fsd1l, Drer\trim8b, Drer\ftr82, Drer\trim35-36, Drer\trim62, Drer\trim35-13, Drer\trim35-25, Drer\trim35-28, Drer\trim35-39, Drer\LOC558300, Drer\zgc:172170, Drer\zgc:92594, Drer\trim101, Drer\trim55a, Drer\btr22, Drer\trim3b, Drer\trim59, Drer\trim35-19, Drer\trim13, Drer\trim35-23, Drer\ftr56, Drer\ftr73, Drer\trim35-31, Drer\trim65, Drer\btr12, Drer\trim35-10, Drer\trim35-29, Drer\trim63a, Drer\si:ch211-12p12.2, Drer\mid2, Drer\trim9, Drer\trim35-3, Drer\trim35-21, Drer\trim63b, Drer\trim46b, Drer\trim109, Drer\ftr83, Drer\btr09, Drer\ftr41, Drer\ftr14, Drer\trim35-35, Drer\ftr24, Drer\ftr84, Drer\si:ch73-106l15.2, Drer\ftr43, Drer\trim35-34, Drer\fsd1, Drer\trim47, Drer\trim46a, Drer\ftr72, Drer\si:ch211-175l6.2, Drer\si:ch211-276c2.4, Drer\cmya5, Drer\btr20, Drer\trim8a, Drer\trim54, Drer\trim25, Drer\trim67, Drer\si:ch73-166o21.1, Drer\trim35-22, Drer\LOC100006839, Drer\ftr70, Drer\btr33, Drer\trim3a, Drer\trim55b, Drer\trim2a, Drer\trim36, Drer\mid1, Drer\zgc:173581, Drer\si:dkey-46i9.6, Drer\si:ch211-216p19.6, Drer\bty, Drer\trim35-20, Drer\btr29, Drer\zgc:136302" - Cele\madd-2 "Xtro\trim55, Xtro\trim9, Xtro\fsd1l, Xtro\trim13, Xtro\trim67, Xtro\mid1, Xtro\trim36, Xtro\trim63" "Mmus\Trim12c, Mmus\Trim9, Mmus\Trim54, Mmus\Trim8, Mmus\Trim69, Mmus\Trim50, Mmus\Mid2, Mmus\Trim17, Mmus\Trim14, Mmus\Trim80, Mmus\Trim67, Mmus\Trim75, Mmus\Trim42, Mmus\Trim36, Mmus\Trim16, Mmus\Trim59, Mmus\Trim13, Mmus\Trim38, Mmus\Fsd2, Mmus\Fsd1l, Mmus\Trim3, Mmus\Trim55, Mmus\Mid1, Mmus\Trim43b, Mmus\Trim43c, Mmus\Trim30a, Mmus\Trim25, Mmus\Trim2, Mmus\Trim56, Mmus\Trim62, Mmus\Trim31, Mmus\Trim46, Mmus\Trim43a, Mmus\Fsd1, Mmus\Trim63" "Hsap\TRIM14, Hsap\TRIM3, Hsap\TRIM62, Hsap\TRIM13, Hsap\FSD1, Hsap\TRIM5, Hsap\TRIM22, Hsap\MID2, Hsap\TRIM56, Hsap\TRIM31, Hsap\TRIM50, Hsap\TRIM38, Hsap\TRIM63, Hsap\FSD2, Hsap\TRIM2, Hsap\TRIM54, Hsap\TRIM10, Hsap\TRIM59, Hsap\FSD1L, Hsap\TRIM55, Hsap\TRIM27, Hsap\TRIM46, Hsap\TRIM8, Hsap\TRIM69, Hsap\TRIM60, Hsap\TRIM42, Hsap\TRIM67, Hsap\TRIM9, Hsap\MID1, Hsap\TRIM17, Hsap\TRIM25, Hsap\TRIM36" "neuroanatomy defective,viable,fertile,locomotor behavior defective,somatic clone,lethal,visible" "ventral nerve cord commissure,class IV dendritic arborizing neuron,wing,dopaminergic neuron,midline crossing tract,ventral multidendritic neuron vdaB,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,somatic clone | third instar larval stage,ectopic,ganglion mother cell,trichogen cell" DRSC02242 E 0.144096503 -0.063856244 -1.89865789 0.494458012 -0.111217673 -0.770306922 FBgn0083299 E(smoDN)1824 Enhancer of smoDN 1824 http://flybase.org/reports/FBgn0083299 gene - - - E(smoDN)1824 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085307 CG34278 - http://flybase.org/reports/FBgn0085307 protein_coding_gene - - - CG34278 - CG34278 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027332 l(1)G0013 lethal (1) G0013 http://flybase.org/reports/FBgn0027332 - gene - - - l(1)G0013 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060811 l(3)S054515 lethal (3) S054515 http://flybase.org/reports/FBgn0060811 gene - - - "0545/15, l(3)S054515" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0052391 CG32391 - http://flybase.org/reports/FBgn0052391 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32391 - CG32391 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003143 pra prawny abdomen http://flybase.org/reports/FBgn0003143 - gene - - - pra - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,poor" "adult thorax,adult abdomen,wing" FBgn0016925 run::Hsap\RUNX1 run::Hsap\RUNX1 http://flybase.org/reports/FBgn0016925 - engineered_fusion_gene - - - "run::Hsap\AML1, run::Hsap\RUNX1, run::Hsap\CBFA2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026377 RalBp-like Retinal-binding protein like http://flybase.org/reports/FBgn0026377 - gene retinoid binding ; GO:0005501 | inferred from sequence or structural similarity - cytoplasm ; GO:0005737 | inferred from direct assay RalBp-like - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063397 Stalker2\ORF2 Stalker2 element ORF2 http://flybase.org/reports/FBgn0063397 transposable_element_gene - - - "rom\ORF2, Stalker2\ORF2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085427 CG34398 - http://flybase.org/reports/FBgn0085427 protein_coding_gene - - - "CG34398, CG15867, CG9487" - CG34398 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "anterior crossvein,wing" FBgn0261995 CG42813 - http://flybase.org/reports/FBgn0261995 protein_coding_gene "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ; GO:0016818 | inferred from electronic annotation with InterPro:IPR004385 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR004385" - - "CG42813, Nudix, CG31063, CG6001" "IPR015797:NUDIX hydrolase domain-like, IPR004385:Nucleoside diphosphate pyrophosphatase, IPR000086:NUDIX hydrolase domain" CG42813 11-Aug-17 DroID_v2017_08 "Drer\nudt5, Drer\nudt14" Scer\YSA1 "Cele\ndx-2, Cele\C50F4.16" Xtro\nudt5 "Mmus\Nudt5, Mmus\Nudt14" "Hsap\NUDT14, Hsap\NUDT5" FBgn0035734 CG14823 - http://flybase.org/reports/FBgn0035734 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR008597 - - CG14823 IPR008597:Destabilase CG14823 11-Aug-17 DroID_v2017_08 - - "Cele\ilys-1, Cele\ilys-2, Cele\ilys-5, Cele\ilys-4, Cele\ilys-3, Cele\ilys-6" - - - FBgn0040045 CR12460 - http://flybase.org/reports/FBgn0040045 pseudogene_attribute - - - "CG40051, CG12460, CR12460" - CR12460 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20970 I 2.040637879 1.564803824 0.689333008 1.191313271 0.460100374 0.36200166 FBgn0265448 CR44348 - http://flybase.org/reports/FBgn0265448 non_protein_coding_gene - - - CR44348 - CR44348 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031683 CG4230 - http://flybase.org/reports/FBgn0031683 protein_coding_gene - - - CG4230 - CG4230 11-Aug-17 DroID_v2017_08 Drer\hax1 - - - Mmus\Hax1 Hsap\HAX1 viable FBgn0066328 rijiy rijiy http://flybase.org/reports/FBgn0066328 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "rijiy, rijiy I" - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,memory defective" FBgn0060401 l(3)S131404 lethal (3) S131404 http://flybase.org/reports/FBgn0060401 gene - - - "1314/04, l(3)S131404" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031128 hydra hydra http://flybase.org/reports/FBgn0031128 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG1338, hydra" "IPR029017:Enolase N-terminal domain-like, IPR022079:Protein of unknown function DUF3629" CG1338 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033778 CG3790 - http://flybase.org/reports/FBgn0033778 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 response to ethanol ; GO:0045471 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 "CG3790, CT" "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG3790 11-Aug-17 DroID_v2017_08 "Drer\slc22a23, Drer\sv2c, Drer\slc22a16, Drer\zgc:175176, Drer\slc22a15, Drer\slc22a7b.1, Drer\slc22a4, Drer\slc22a6l, Drer\slc22a7a, Drer\sv2bb, Drer\si:dkey-166k12.1, Drer\sv2a, Drer\nln, Drer\zgc:153639, Drer\slc22a13, Drer\slc22a17, Drer\LOC100334012, Drer\thop1, Drer\slc22a31, Drer\slc22a2, Drer\svopa" "Scer\PRD1, Scer\JEN1, Scer\PHO84, Scer\GIT1" "Cele\oct-2, Cele\oct-1, Cele\B0361.11, Cele\K05F1.6, Cele\Y82E9BR.16, Cele\B0252.3, Cele\ZK550.3, Cele\svop-1, Cele\F45E10.2" "Xtro\sv2b, Xtro\slc22a5, Xtro\slc22a13, Xtro\slc22a15.2, Xtro\slc22a6, Xtro\sv2c, Xtro\svop, Xtro\slc22a4, Xtro\sv2a" "Mmus\Slc22a1, Mmus\Sv2c, Mmus\Slc22a23, Mmus\Slc22a15, Mmus\Slc22a16, Mmus\Slc22a4, Mmus\Slc22a6, Mmus\Slc22a7, Mmus\Svop, Mmus\Slc22a28, Mmus\Slc22a21, Mmus\Slc22a5, Mmus\Slc22a20, Mmus\Slc22a8, Mmus\Slc22a13, Mmus\Slc22a17, Mmus\Slc22a2, Mmus\Sv2b, Mmus\Sv2a, Mmus\Slc22a3, Mmus\Nln, Mmus\Thop1, Mmus\Slc22a12" "Hsap\SLC22A25, Hsap\SV2A, Hsap\NLN, Hsap\THOP1, Hsap\SLC22A20, Hsap\SVOP, Hsap\SLC22A2, Hsap\SLC22A17, Hsap\SLC22A23, Hsap\SLC22A3, Hsap\SV2B, Hsap\SLC22A6, Hsap\SLC22A16, Hsap\SLC22A8, Hsap\SLC22A4, Hsap\SLC22A13, Hsap\SLC22A1, Hsap\SLC22A5, Hsap\SLC22A12, Hsap\SLC22A31, Hsap\SV2C, Hsap\SLC22A15, Hsap\SLC22A7" "viable,fertile" FBgn0036155 CG6163 - http://flybase.org/reports/FBgn0036155 protein_coding_gene - - - CG6163 IPR006578:MADF domain CG6163 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060838 l(3)S049604 lethal (3) S049604 http://flybase.org/reports/FBgn0060838 gene - - - "0496/04, l(3)S049604" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015277 Pi3K59F Phosphotidylinositol 3 kinase 59F http://flybase.org/reports/FBgn0015277 - protein_coding_gene "1-phosphatidylinositol-3-kinase activity ; GO:0016303 | inferred from sequence or structural similarity with SGD:S000004230 1-phosphatidylinositol-3-kinase activity ; GO:0016303 | inferred from direct assay phosphatidylinositol-4,5-bisphosphate 3-kinase activity ; GO:0046934 | NOT inferred from direct assay phosphatidylinositol 3-kinase activity ; GO:0035004 | non-traceable author statement 1-phosphatidylinositol-4-phosphate 3-kinase activity ; GO:0035005 | NOT inferred from direct assay" "phosphatidylinositol-mediated signaling ; GO:0048015 | inferred from electronic annotation with InterPro:IPR008290, InterPro:IPR015433 autophagy ; GO:0006914 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype inferred from genetic interaction with Atg6 regulation of autophagy ; GO:0010506 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype positive regulation of nurse cell apoptotic process ; GO:0045850 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype phosphatidylinositol phosphorylation ; GO:0046854 | non-traceable author statement cellular response to starvation ; GO:0009267 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype phosphatidylinositol phosphorylation ; GO:0046854 | inferred from sequence or structural similarity with SGD:S000004230 phosphatidylinositol phosphorylation ; GO:0046854 | inferred from direct assay" "phosphatidylinositol 3-kinase complex, class III ; GO:0035032 | non-traceable author statement autophagosome membrane ; GO:0000421 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay phosphatidylinositol 3-kinase complex, class III, type I ; GO:0034271 | inferred from direct assay" "PI3K, dPI3K, CG5373, PI(3)K, PI3K-59F, PI3K_59F, DmVps34, VPS34, Pi3K59F, Vps34, vps34, PI[[3]]K, Pi3K_59F, dVps34/PI3K59F, dVps34" "IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR001263:Phosphoinositide 3-kinase, accessory (PIK) domain, IPR002420:Phosphatidylinositol 3-kinase, C2 domain, IPR008290:Phosphatidylinositol 3-kinase, Vps34 type, IPR011009:Protein kinase-like domain, IPR015433:Phosphatidylinositol kinase, IPR016024:Armadillo-type fold, IPR000008:C2 domain" CG5373 11-Aug-17 DroID_v2017_08 Drer\pik3c3 Scer\VPS34 Cele\vps-34 Xtro\pik3c3 Mmus\Pik3c3 Hsap\PIK3C3 "viable,fertile,lethal,starvation stress response defective" "autophagic vacuole | conditional | somatic clone,lysosome | conditional | somatic clone,embryonic/larval fat body,conditional,somatic clone,garland cell,eye disc,autophagic vacuole | somatic clone,nurse cell,germline clone,somatic clone | third instar larval stage,pre-autophagosomal structure membrane | conditional | somatic clone,embryonic/larval fat body | late third instar larval stage" DRSC04640 K -0.456494315 -0.055820369 0.033462154 0.123662986 0.505035764 1.581710572 FBgn0004535 l(4)102ABg lethal (4) 102ABg http://flybase.org/reports/FBgn0004535 - gene - - - "l(4)24, l(4)102ABg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0032754 CG10700 - http://flybase.org/reports/FBgn0032754 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR016156, InterPro:IPR017941, InterPro:IPR023753 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR017941 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR016156" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR004099, InterPro:IPR016156, InterPro:IPR017941, InterPro:IPR023753 execution phase of apoptosis ; GO:0097194 | inferred from sequence or structural similarity with UniProtKB:Q96NN9" - CG10700 "IPR023753:FAD/NAD(P)-binding domain, IPR016156:FAD/NAD-linked reductase, dimerisation domain, IPR017941:Rieske [2Fe-2S] iron-sulphur domain" CG10700 11-Aug-17 DroID_v2017_08 "Drer\aifm3, Drer\aifm4, Drer\aifm2, Drer\aifm5" Scer\AIF1 Cele\F20D6.11 "Xtro\aifm3, Xtro\LOC100498581, Xtro\aifm2" Mmus\Aifm3 Hsap\AIFM3 FBgn0267221 CR45661 - http://flybase.org/reports/FBgn0267221 non_protein_coding_gene - - - CR45661 - CR45661 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040269 T:SS-wg Signal sequence of wg http://flybase.org/reports/FBgn0040269 engineered_tag - - - "T:SS-wg, T:wg" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283649 elgi early girl http://flybase.org/reports/FBgn0283649 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR013323 acid-amino acid ligase activity ; GO:0016881 | inferred from electronic annotation with InterPro:IPR015036 protein tag ; GO:0031386 | inferred from electronic annotation with InterPro:IPR015036 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:18401 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A zinc ion binding ; GO:0008270 | inferred from sequence model" protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:18401 regulation of meiotic cell cycle ; GO:0051445 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG17033, elgi, dNrdp1, Nrdp1" "IPR001841:Zinc finger, RING-type, IPR008974:TRAF-like, IPR015036:USP8 interacting, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17033 11-Aug-17 DroID_v2017_08 "Drer\rnf151, Drer\rnf41" - "Cele\trf-1, Cele\B0432.13" Xtro\rnf41 "Mmus\Rnf151, Mmus\Rnf41" "Hsap\RNF41, Hsap\TRAIP, Hsap\RNF151" "partially lethal - majority die,visible" "mesothoracic tergum,oocyte" DRSC10242 K -0.14044362 0.160000067 -0.497540236 0.464587119 2.217056269 0.745057763 FBgn0267417 CG45770 - http://flybase.org/reports/FBgn0267417 protein_coding_gene - - - "CG45770, Mst77Y" - CG45770 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267812 CR46137 - http://flybase.org/reports/FBgn0267812 non_protein_coding_gene - - - CR46137 - CR46137 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005587 anon-alaA anon-alaA http://flybase.org/reports/FBgn0005587 FBgn0004553 repeat_region - - - "ALA-A, ala-A, ALA-repeat, anon-alaA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085563 CG41233 - http://flybase.org/reports/FBgn0085563 protein_coding_gene - - - CG41233 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264349 CR43805 - http://flybase.org/reports/FBgn0264349 non_protein_coding_gene - - - CR43805 - CR43805 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036860 CG14086 - http://flybase.org/reports/FBgn0036860 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG14086 IPR032055:Transmembrane protein 72 CG14086 11-Aug-17 DroID_v2017_08 Drer\tmem72 - - - Mmus\Tmem72 Hsap\TMEM72 viable FBgn0053388 5SrRNA:CR33388 5SrRNA:CR33388 http://flybase.org/reports/FBgn0053388 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33388, 5SrRNA:CR33388" - CR33388 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038901 Burs Bursicon http://flybase.org/reports/FBgn0038901 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:Q9VJS7 neuropeptide hormone activity ; GO:0005184 | contributes_to inferred by curator from GO:0031395 neuropeptide receptor binding ; GO:0071855 | contributes_to inferred from physical interaction with rk hormone activity ; GO:0005179 | inferred from mutant phenotype neuropeptide hormone activity ; GO:0005184 | contributes_to inferred from direct assay intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype chitin-based cuticle sclerotization ; GO:0007593 | inferred from mutant phenotype border follicle cell delamination ; GO:0030709 | inferred from mutant phenotype bursicon neuropeptide hormone complex ; GO:0031395 | inferred from physical interaction with Pburs terminal bouton ; GO:0043195 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay bursicon neuropeptide hormone complex ; GO:0031395 | inferred from direct assay "CG13419, bursalpha, frl, Bursalpha, burs-alpha, BURS, Burs-alpha, burs, burs alpha, Burs, Burs alpha, Bur alpha" "IPR006207:Cystine knot, C-terminal, IPR029034:Cystine-knot cytokine, IPR004133:DAN" CG13419 11-Aug-17 DroID_v2017_08 - - - - Mmus\Muc5b - "viable,visible,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,adult cuticle,adult abdomen,posterior scutellar bristle,adult thorax" FBgn0263086 CG43354 - http://flybase.org/reports/FBgn0263086 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43354, lincRNA.182" - CG43354 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003989 vr varnished http://flybase.org/reports/FBgn0003989 - gene - - - vr - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "eye,ommatidium" FBgn0267958 CR46238 - http://flybase.org/reports/FBgn0267958 non_protein_coding_gene - - - "CR46238, lincRNA.760" - CR46238 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011077 l(1)Q31 lethal (1) Q31 http://flybase.org/reports/FBgn0011077 FBgn0010210 gene - - - l(1)Q31 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028887 CG3491 - http://flybase.org/reports/FBgn0028887 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR026741" - "BG:DS03323.1, CG3491" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026937:Strawberry notch, helicase C domain, IPR026741:Protein strawberry notch" CG3491 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-63e15.2, Drer\sbno1, Drer\sbno2a" - Cele\let-765 Xtro\sbno2 "Mmus\Sbno1, Mmus\Sbno2" "Hsap\SBNO1, Hsap\SBNO2" viable FBgn0262000 CG42818 - http://flybase.org/reports/FBgn0262000 protein_coding_gene - - - "CG42818, DS07473.1A, BG:DS07473.1, CG12455" - CG42818 11-Aug-17 DroID_v2017_08 "Drer\cacna2d1a, Drer\cacna2d4a, Drer\cacna2d3, Drer\cacna2d2b, Drer\cacna2d4b, Drer\cachd1" - - "Xtro\cacna2d2, Xtro\cacna2d4, Xtro\cachd1, Xtro\cacna2d1" "Mmus\Cacna2d2, Mmus\Cacna2d3, Mmus\Cacna2d1, Mmus\Cacna2d4, Mmus\Cachd1" "Hsap\CACHD1, Hsap\CACNA2D3, Hsap\CACNA2D2, Hsap\CACNA2D4, Hsap\CACNA2D1" FBgn0263556 mir-4940 mir-4940 stem loop http://flybase.org/reports/FBgn0263556 miRNA_gene - - - "mir-4940, dme-mir-4940, CR43541" - CR43541 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028647 CG11902 - http://flybase.org/reports/FBgn0028647 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "anon-96CDa, CG11902" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11902 11-Aug-17 DroID_v2017_08 "Drer\znf574, Drer\znf1035, Drer\znf1007, Drer\si:ch211-216l23.1, Drer\znf1004, Drer\znf366, Drer\si:dkey-253d23.2, Drer\znf710b, Drer\znf1010, Drer\si:ch211-261d7.6, Drer\si:ch211-266d19.4, Drer\znf407, Drer\zgc:66448, Drer\si:dkey-30k6.5, Drer\znf710a, Drer\znf142, Drer\znf983" - Cele\Y48G8AL.10 "Xtro\znf142, Xtro\znf423, Xtro\znf91" "Mmus\Zfp423, Mmus\Zfp62, Mmus\Zfp710, Mmus\Gm14124, Mmus\Zfp366, Mmus\Zfp521, Mmus\Zfp236, Mmus\Zfp142, Mmus\Zfp865, Mmus\Zfp729a, Mmus\Zfp619, Mmus\Zfp646" "Hsap\ZNF521, Hsap\ZNF423, Hsap\ZNF808, Hsap\ZFP62, Hsap\ZNF197, Hsap\ZNF710, Hsap\ZNF226, Hsap\ZNF850, Hsap\ZNF836, Hsap\ZNF845, Hsap\ZNF366, Hsap\ZNF407, Hsap\ZNF236, Hsap\ZNF780B, Hsap\ZNF99, Hsap\ZNF462, Hsap\ZNF624, Hsap\ZNF91, Hsap\ZNF585A, Hsap\ZNF729, Hsap\ZNF208, Hsap\ZNF646, Hsap\ZNF721" viable FBgn0001157 gustE gustatory-defective E http://flybase.org/reports/FBgn0001157 - gene - - - gustE - - 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,recessive" taste bristle FBgn0060666 l(3)S080503 lethal (3) S080503 http://flybase.org/reports/FBgn0060666 gene - - - "0805/03, l(3)S080503" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265365 CR44306 - http://flybase.org/reports/FBgn0265365 non_protein_coding_gene - - - CR44306 - CR44306 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065644 l(2)SH0753 lethal (2) SH0753 http://flybase.org/reports/FBgn0065644 gene - - - "l(2)SH0753, l(2)SH2 0753" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010112 fs(1)de4 female sterile (1) defective eggs 4 http://flybase.org/reports/FBgn0010112 - gene - - - "de4, fs(1)de4" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "endochorion,dorsal appendage,chorion" FBgn0035333 CG1317 - http://flybase.org/reports/FBgn0035333 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000322018 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:30550 zinc ion binding ; GO:0008270 | inferred from sequence model protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:30550 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000322018 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000322018 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from sequence or structural similarity with HGNC:30550 CG1317 "IPR011016:Zinc finger, RING-CH-type, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1317 11-Aug-17 DroID_v2017_08 "Drer\march2, Drer\zgc:158785, Drer\march6, Drer\march4, Drer\zgc:153256, Drer\march11, Drer\march9, Drer\march7, Drer\march8" Scer\SSM4 "Cele\marc-5, Cele\marc-1, Cele\marc-6" "Xtro\march2, Xtro\march7, Xtro\march3, Xtro\march6, Xtro\march1, Xtro\march8, Xtro\march4, Xtro\march11, Xtro\march9" "Mmus\March1, Mmus\March9, Mmus\March11, Mmus\March3, Mmus\March10, Mmus\March6, Mmus\March8, Mmus\March2, Mmus\March4" "Hsap\MARCH1, Hsap\MARCH2, Hsap\MARCH9, Hsap\MARCH6, Hsap\MARCH4, Hsap\MARCH10, Hsap\MARCH8, Hsap\MARCH7, Hsap\MARCH11, Hsap\MARCH3" "viable,fertile" FBgn0265634 CR44441 - http://flybase.org/reports/FBgn0265634 non_protein_coding_gene - - - "CR44441, lincRNA.S8353" - CR44441 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002415 l(3)DTS2 lethal (3) DTS2 http://flybase.org/reports/FBgn0002415 - gene - - - "DTS-2, l(3)DTS2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039938 Sox102F Sox102F http://flybase.org/reports/FBgn0039938 protein_coding_gene - positive regulation of heart contraction ; GO:0045823 | inferred from mutant phenotype - "CG11153, Sox D, SOXD, SOX102D, SoxD, Sox102D, Sox102F" IPR009071:High mobility group box domain CG11153 11-Aug-17 DroID_v2017_08 "Drer\sox6, Drer\sox5" Scer\ROX1 Cele\egl-13 "Xtro\sox13, Xtro\sox6, Xtro\sox5" "Mmus\Sox6, Mmus\Sox13, Mmus\Sox5" "Hsap\SOX6, Hsap\SOX5, Hsap\SOX13" "visible,viable" "adult heart,myofibrilhow-24B,wing,wing vein L2,wing vein L3,ectopic,eye" FBgn0013245 E(var)27 E(var)27 http://flybase.org/reports/FBgn0013245 - gene - - - E(var)27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0000185 bie bientot http://flybase.org/reports/FBgn0000185 - gene - - - bie - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,visible,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,maternal effect" "stage 5 embryo,embryonic/first instar larval cuticle,tergite" FBgn0032899 CG9338 - http://flybase.org/reports/FBgn0032899 protein_coding_gene - - - "BcDNA:GH07967, CG9338" - CG9338 11-Aug-17 DroID_v2017_08 - - "Cele\C15H9.9, Cele\K11H12.7, Cele\F35C5.11, Cele\K11H12.6" - - - viable DRSC24503 K -0.326292227 0.258428317 -0.185042133 -0.249631514 -0.100595605 -1.67004944 FBgn0263627 CR43636 - http://flybase.org/reports/FBgn0263627 non_protein_coding_gene - - - CR43636 - CR43636 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000211 bra breakage during anaphase http://flybase.org/reports/FBgn0000211 - gene - - - bra - - 11-Aug-17 DroID_v2017_08 - - - - - - mitotic cell cycle defective FBgn0002915 mc-44A mc-44A http://flybase.org/reports/FBgn0002915 - gene - - - "Myc, Dmmyc, Dmc, mc-44A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032894 CG14402 - http://flybase.org/reports/FBgn0032894 protein_coding_gene - - - "BcDNA:AT08210, CG14402" - CG14402 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02386 I 1.739232661 -0.122428543 0.540751925 -0.371056164 0.056215841 0.608063791 FBgn0082968 snoRNA:Psi28S-3316e snoRNA:Psi28S-3316e http://flybase.org/reports/FBgn0082968 snoRNA_gene - - - "snoRNA:Psi28S-3316e, Psi28S-3316e, psi28S-3316e, CR34554" - CR34554 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010793 l(3)03077 lethal (3) 03077 http://flybase.org/reports/FBgn0010793 - gene - - - l(3)03077 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011090 l(1)Q50 lethal (1) Q50 http://flybase.org/reports/FBgn0011090 FBgn0010210 gene - - - l(1)Q50 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267269 lncRNA:TS11 long noncoding RNA: testis-specific 11 http://flybase.org/reports/FBgn0267269 non_protein_coding_gene - - - "CR45705, lncRNA:TS11, lncRNA:TS19, lncRNA:TS21" - CR45705 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051673 CG31673 - http://flybase.org/reports/FBgn0051673 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR006139 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" - "CG9332, BcDNA:LD14730, CG31673, CCG31673" "IPR006139:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040:NAD(P)-binding domain, IPR029753:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site" CG31673 11-Aug-17 DroID_v2017_08 "Drer\zgc:136493, Drer\mthfd2, Drer\grhpra, Drer\grhprb, Drer\mthfd2l" "Scer\SER3, Scer\YGL185C, Scer\YPL113C, Scer\SER33, Scer\FDH1, Scer\GOR1" - "Xtro\grhpr.2, Xtro\mthfd2l, Xtro\grhpr.1, Xtro\mthfd2" "Mmus\Grhpr, Mmus\Mthfd2l, Mmus\Mthfd2" "Hsap\GRHPR, Hsap\MTHFD2, Hsap\MTHFD2L" viable FBgn0001464 l(1)7Ee lethal (1) 7Ee http://flybase.org/reports/FBgn0001464 - gene - - - l(1)7Ee - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260569 MENE-MM15 - http://flybase.org/reports/FBgn0260569 gene - - - MENE-MM15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "hyperplasia,somatic clone" "eye disc,somatic clone" FBgn0005310 ms(1)RD33 male sterile (1) RD33 http://flybase.org/reports/FBgn0005310 - gene - - - ms(1)RD33 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "spermatocyte,spermatid" FBgn0083065 rpn rantanplan http://flybase.org/reports/FBgn0083065 gene - - - rpn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070005 BG01526 BG01526 http://flybase.org/reports/FBgn0070005 gene - - - BG01526 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0260088 2L0028 - http://flybase.org/reports/FBgn0260088 gene - - - 2L0028 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0002545 lf little fly http://flybase.org/reports/FBgn0002545 - gene - - - "12, lT2-14a, lN5, l152, 9, l(1)19Ee, lf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced,fertile,visible,lethal,recessive" adult abdomen FBgn0046650 anon-38D.15 anon-38D.15 http://flybase.org/reports/FBgn0046650 gene - - - "38D.15, anon-38D.15" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005031 E(M99E) Enhancer of Minute(3)99E http://flybase.org/reports/FBgn0005031 - gene - - - "E(M3g), E(M99E)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259344 C478 - http://flybase.org/reports/FBgn0259344 gene - - - C478 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0051427 CR31427 - http://flybase.org/reports/FBgn0051427 pseudogene_attribute metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR014782 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR014782 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001930 - "CG11955, CG31427, CR31427" "IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CR31427 11-Aug-17 DroID_v2017_08 "Drer\erap2, Drer\enpep, Drer\si:ch211-149p5.1, Drer\erap1b, Drer\lnpep, Drer\npepps, Drer\si:ch211-276a23.5, Drer\si:ch211-198g19.1, Drer\anpepb, Drer\si:ch211-106j24.1, Drer\anpepa, Drer\erap1a" "Scer\APE2, Scer\AAP1, Scer\TMA108" "Cele\T07F10.1, Cele\Y53F4B.20, Cele\AC3.5, Cele\T12E12.6, Cele\R03G8.6, Cele\pam-1, Cele\Y67D8C.9, Cele\Y42A5A.1, Cele\VB0395L.1, Cele\F49B2.6, Cele\T16G12.1, Cele\R03G8.4, Cele\mnp-1" "Xtro\erap1, Xtro\npepps, Xtro\lnpep, Xtro\lvrn, Xtro\anpep, Xtro\enpep" "Mmus\Anpep, Mmus\Lnpep, Mmus\Lvrn, Mmus\Enpep, Mmus\Trhde, Mmus\Npepps, Mmus\Erap1" "Hsap\TRHDE, Hsap\NPEPPS, Hsap\LNPEP, Hsap\LVRN, Hsap\ANPEP, Hsap\ERAP1, Hsap\ENPEP, Hsap\ERAP2" DRSC22675 K -0.077291304 0.39392392 -0.016155036 0.298486407 1.87596726 -0.184063301 FBgn0013700 mt:tRNA:Met-CAT mitochondrial transfer RNA:Methionine-CAT http://flybase.org/reports/FBgn0013700 FBgn0002867 tRNA_gene - - - "CR34062, tRNA[Met], tRNA[f-met], tRNA-Met, mtdbD00006294, mt:tRNA:Met-CAT, mt:tRNA:M" - CR34062 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003558 Su(er) Suppressor of erupt http://flybase.org/reports/FBgn0003558 - gene - - - Su(er) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060550 l(3)S098502 lethal (3) S098502 http://flybase.org/reports/FBgn0060550 gene - - - "0985/02, l(3)S098502" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266242 CR44937 - http://flybase.org/reports/FBgn0266242 non_protein_coding_gene - - - "CR44937, lincRNA.733" - CR44937 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031893 MICU1 Mitochondrial calcium uptake 1 http://flybase.org/reports/FBgn0031893 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 anesthesia-resistant memory ; GO:0007615 | inferred from mutant phenotype positive regulation of mitochondrial calcium ion concentration ; GO:0051561 | inferred from sequence or structural similarity with UniProtKB:Q9BPX6 medium-term memory ; GO:0072375 | inferred from mutant phenotype calcium ion transmembrane import into mitochondrion ; GO:0036444 | inferred from mutant phenotype - "CG4495, MICU1" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG4495 11-Aug-17 DroID_v2017_08 "Drer\micu3a, Drer\micu1, Drer\micu3b, Drer\micu2" - Cele\micu-1 "Xtro\micu2, Xtro\micu1" "Mmus\Micu1, Mmus\Micu3, Mmus\Micu2" "Hsap\MICU1, Hsap\MICU3, Hsap\MICU2" "partially lethal - majority die,some die during pupal stage" DRSC02752 K 0.112096133 -0.310052943 -0.312297822 -0.507856105 1.961459342 -1.07381608 FBgn0011111 l(1)Q72 lethal (1) Q72 http://flybase.org/reports/FBgn0011111 FBgn0010210 gene - - - l(1)Q72 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085241 CG34212 - http://flybase.org/reports/FBgn0085241 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34212 - CG34212 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085689 CG41558 - http://flybase.org/reports/FBgn0085689 protein_coding_gene - - - CG41558 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086207 E(ls)3 - http://flybase.org/reports/FBgn0086207 gene - - - E(ls)3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010240 Lcch3 Ligand-gated chloride channel homolog 3 http://flybase.org/reports/FBgn0010240 - protein_coding_gene GABA-A receptor activity ; GO:0004890 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000435002 GABA-gated chloride ion channel activity ; GO:0022851 | inferred from direct assay "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR002289, InterPro:IPR006028, InterPro:IPR006029, InterPro:IPR006201" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201 plasma membrane ; GO:0005886 | inferred from direct assay GABA-A receptor complex ; GO:1902711 | inferred from biological aspect of ancestor with PANTHER:PTN000435002" "DmGA_b, DmGABAbeta, LCCH3, CG17336, Lcch3, CT38330" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002289:Gamma-aminobutyric-acid A receptor, beta subunit, IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG17336 11-Aug-17 DroID_v2017_08 "Drer\gabra6a, Drer\gabrp, Drer\gabrb4, Drer\LOC100330554, Drer\gabrz, Drer\glra2, Drer\glra4b, Drer\si:dkey-155h10.3, Drer\glrba, Drer\gabrr1, Drer\glra4a, Drer\LOC561083, Drer\gabrb2, Drer\glrbb, Drer\gabra1, Drer\si:dkey-52k1.6, Drer\gabra6b, Drer\gabra5, Drer\gabrr2b, Drer\LOC562831, Drer\gabrd, Drer\glra3, Drer\LOC100001259, Drer\zgc:110204, Drer\gabrg2, Drer\gabrr3a, Drer\gabrr2a, Drer\gabrb1, Drer\gabrb3" - "Cele\lgc-41, Cele\glc-2, Cele\mod-1, Cele\lgc-37, Cele\gab-1, Cele\lgc-38, Cele\avr-15, Cele\glc-3, Cele\lgc-44, Cele\lgc-36, Cele\lgc-40, Cele\unc-49, Cele\glc-4, Cele\lgc-42, Cele\lgc-39, Cele\ggr-1, Cele\avr-14" "Xtro\gabra2, Xtro\gabrr3, Xtro\gabra6, Xtro\gabrg2, Xtro\glrb, Xtro\gabrb2, Xtro\LOC100490720, Xtro\glra3, Xtro\gabrb3, Xtro\gabrd, Xtro\gabrp, Xtro\glra2, Xtro\glra1, Xtro\gabra5" "Mmus\Glra3, Mmus\Gabrp, Mmus\Gabrg1, Mmus\Gabrb2, Mmus\Gabre, Mmus\Gabra3, Mmus\Gabra2, Mmus\Gabrg2, Mmus\Gabra1, Mmus\Glrb, Mmus\Gabrd, Mmus\Gabrr1, Mmus\Gabra5, Mmus\Glra1, Mmus\Gabrb1, Mmus\Glra4, Mmus\Gabrb3, Mmus\Gabrg3, Mmus\Gabrr3, Mmus\Gabrq, Mmus\Glra2, Mmus\Gabra6, Mmus\Gabrr2" "Hsap\GABRG3, Hsap\GABRG2, Hsap\GABRR1, Hsap\GABRP, Hsap\GLRA3, Hsap\GABRA5, Hsap\GABRB3, Hsap\GABRA2, Hsap\GABRE, Hsap\GLRB, Hsap\GLRA1, Hsap\GABRA6, Hsap\GABRG1, Hsap\GABRA1, Hsap\GABRA4, Hsap\GLRA2, Hsap\GABRR2, Hsap\GABRR3, Hsap\GABRB1, Hsap\GLRA4, Hsap\GABRQ, Hsap\GABRD, Hsap\GABRB2" viable FBgn0035789 mthl6 methuselah-like 6 http://flybase.org/reports/FBgn0035789 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "CG16992, anon-WO0170980.128, anon-WO0170980.127, mthl6" "IPR017981:GPCR, family 2-like, IPR010596:Methuselah, N-terminal domain, IPR000832:GPCR, family 2, secretin-like, IPR022343:GCR1-cAMP receptor, IPR023311:Methuselah ectodomain, domain 2" CG16992 11-Aug-17 DroID_v2017_08 "Drer\adgrf11, Drer\adgrg6" - Cele\lat-2 Xtro\gpr157 Mmus\Adgre1 - viable FBgn0263561 mir-4984 mir-4984 stem loop http://flybase.org/reports/FBgn0263561 miRNA_gene - - - "mir-4984, dme-mir-4984, CR43546" - CR43546 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051266 CG31266 - http://flybase.org/reports/FBgn0051266 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SPH146, CG5240, CG31266" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG31266 11-Aug-17 DroID_v2017_08 "Drer\try, Drer\zgc:171509, Drer\prss59.2, Drer\zmp:0000001088" - Cele\svh-1 - "Mmus\Klk14, Mmus\Klk7, Mmus\Prss54, Mmus\Prss1, Mmus\Prss3, Mmus\Klk1b21, Mmus\Prss55, Mmus\Cfd" "Hsap\KLK14, Hsap\PRSS3, Hsap\CFD, Hsap\KLK7" viable FBgn0028018 l(3)S104913b lethal (3) S104913b http://flybase.org/reports/FBgn0028018 gene - - - "1049/13, l(3)S104913, l(3)S104913b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0036848 CG10424 - http://flybase.org/reports/FBgn0036848 protein_coding_gene ADP-dependent NAD(P)H-hydrate dehydratase activity ; GO:0052855 | inferred from electronic annotation with InterPro:IPR000631 - - CG10424 "IPR000631:ATP-dependent (S)-NAD(P)H-hydrate dehydratase, IPR017953:Carbohydrate kinase, predicted, conserved site, IPR029056:Ribokinase-like" CG10424 11-Aug-17 DroID_v2017_08 Drer\carkd Scer\YKL151C Cele\R107.2 Xtro\carkd Mmus\Naxd Hsap\NAXD "viable,fertile" FBgn0259720 CG42374 - http://flybase.org/reports/FBgn0259720 protein_coding_gene - DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR031821 SOSS complex ; GO:0070876 | inferred from electronic annotation with InterPro:IPR031821 "CG42374, Dromel_CG9666_FBtr0074991_uORF" IPR031821:SOSS complex subunit C CG42374 11-Aug-17 DroID_v2017_08 Drer\inip - - Xtro\inip Mmus\Inip Hsap\INIP FBgn0027500 spd-2 spindle defective 2 http://flybase.org/reports/FBgn0027500 FBgn0014928 protein_coding_gene adenosine-diphosphatase activity ; GO:0043262 | inferred from biological aspect of ancestor with PANTHER:PTN000989736 centrosome organization ; GO:0051297 | inferred from mutant phenotype sperm aster formation ; GO:0035044 | inferred from mutant phenotype astral microtubule organization ; GO:0030953 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay pericentriolar material ; GO:0000242 | inferred from direct assay "SPD2, BcDNA:LD24702, anon-73Ba, Spd-2, CG17286, spd-2, D-SPD2, DSPD-2, SPD-2, DSpd-2, D-Spd2, CG17286-PA, spd2, Dspd-2, DSpd2, Spd2, dSpd2, Cep192, Dspd2, CEP192" IPR013783:Immunoglobulin-like fold CG17286 11-Aug-17 DroID_v2017_08 "Drer\nudt9, Drer\si:rp71-15i12.1" - Cele\ndx-6 - "Mmus\Nudt9, Mmus\Cep192" "Hsap\CEP192, Hsap\NUDT9" "lethal,maternal effect,male sterile,viable,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage,female sterile,uncoordinated" "centriole | ectopic,spermatocyte,onion stage spermatid,aster,spermatid,spermatozoon,asterst-j7),centrosomest-j7),primary spermatocyte" FBgn0001045 fs(3)HO127 female sterile (3) HO127 http://flybase.org/reports/FBgn0001045 - gene - - - "fs(3)127A, fs(3)HO127" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile oocyte FBgn0031130 CG15452 - http://flybase.org/reports/FBgn0031130 protein_coding_gene - - - CG15452 - CG15452 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0065304 l(2)SH1975 lethal (2) SH1975 http://flybase.org/reports/FBgn0065304 gene - - - "l(2)SH1975, l(2)SH2 1975" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065094 snmRNA:419 small non-messenger RNA 419 http://flybase.org/reports/FBgn0065094 non_protein_coding_gene - - - "Dm-419, CR33917, snmRNA:419" - CR33917 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032450 CG5776 - http://flybase.org/reports/FBgn0032450 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960" - - CG5776 "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR029067:CDC48 domain 2-like" CG5776 11-Aug-17 DroID_v2017_08 "Drer\spata5l1, Drer\zgc:136908, Drer\vcp, Drer\spata5" "Scer\CDC48, Scer\AFG2" "Cele\cdc-48.2, Cele\cdc-48.1, Cele\cdc-48.3" "Xtro\mecp2, Xtro\vcp, Xtro\spata5" "Mmus\Spata5, Mmus\Vcp" "Hsap\SPATA5L1, Hsap\SPATA5, Hsap\ATAD2B, Hsap\VCP" "viable,visible" trichogen cell FBgn0035228 CG12091 - http://flybase.org/reports/FBgn0035228 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000001118 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000001118 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence model protein dephosphorylation ; GO:0006470 | inferred by curator from GO:0004722 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000001118 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000001118 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000268440 CG12091 IPR001932:PPM-type phosphatase domain CG12091 11-Aug-17 DroID_v2017_08 "Drer\pptc7a, Drer\pptc7b" Scer\PTC7 Cele\W09D10.4 Xtro\pptc7 Mmus\Pptc7 Hsap\PPTC7 viable FBgn0028894 GMF Glia maturation factor http://flybase.org/reports/FBgn0028894 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR002108 Arp2/3 complex binding ; GO:0071933 | inferred from electronic annotation with InterPro:IPR011171 actin binding ; GO:0003779 | inferred from sequence or structural similarity "negative regulation of Arp2/3 complex-mediated actin nucleation ; GO:0034316 | inferred from direct assay inferred from genetic interaction with Arpc5, flr actin filament debranching ; GO:0071846 | inferred from direct assay regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype regulation of cell projection organization ; GO:0031344 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype" perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay lamellipodium ; GO:0030027 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cell periphery ; GO:0071944 | inferred from direct assay "DS02740.9, BG:DS02740.9, BcDNA:SD03793, GMF, CG5869, dGMF, gmf" "IPR002108:Actin-depolymerising factor homology domain, IPR011171:Glia maturation factor, IPR029006:ADF-H/Gelsolin-like domain" CG5869 11-Aug-17 DroID_v2017_08 "Drer\gmfg, Drer\gmfb" Scer\AIM7 Cele\Y50D7A.10 "Xtro\gmfb, Xtro\gmfg" "Mmus\Gmfg, Mmus\Gmfb" "Hsap\GMFG, Hsap\GMFB" viable FBgn0005480 l(1)ts1137 lethal (1) ts1137 http://flybase.org/reports/FBgn0005480 - gene - - - l(1)ts1137 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0028663 VhaM9.7-b Vacuolar H[+] ATPase M9.7 subunit b http://flybase.org/reports/FBgn0028663 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000262636 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from sequence model with Pfam:PF05493 hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from sequence model with InterPro:IPR008389,InterPro:IPR017385" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model inferred from sequence model with Pfam:PF05493" "proton-transporting V-type ATPase, V0 domain ; GO:0033179 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity" "CG7625, Vha M9.7-2, vhaM9.7-2, vhaM9.2-2, anon-WO0118547.551, VhaM9.7-b, VhaM9.7-2, vhaM9.7-b, ATP6V0M9.7-2" "IPR008389:ATPase, V0 complex, subunit e1/e2, IPR017385:ATPase, V0 complex, subunit e1/e2, metazoa" CG7625 11-Aug-17 DroID_v2017_08 "Drer\pars2, Drer\atp6v0e1, Drer\atpv0e2" Scer\VMA9 Cele\vha-17 "Xtro\atp6v0e1, Xtro\atp6v0e2" "Mmus\Atp6v0e, Mmus\Atp6v0e2, Mmus\Pars2" "Hsap\ATP6V0E2, Hsap\ATP6V0E1" "lethal - all die before end of embryonic stage,some die during embryonic stage,body color defective,partially lethal - majority die,some die during pupal stage" "Malpighian tubule,mesothoracic tergum" FBgn0053120 CG33120 - http://flybase.org/reports/FBgn0053120 protein_coding_gene long-chain-alcohol O-fatty-acyltransferase activity ; GO:0047196 | inferred from biological aspect of ancestor with PANTHER:PTN001270476 diacylglycerol O-acyltransferase activity ; GO:0004144 | inferred from biological aspect of ancestor with PANTHER:PTN001270476 triglyceride biosynthetic process ; GO:0019432 | inferred from biological aspect of ancestor with PANTHER:PTN001270476 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001270476 "CG10599, CG33120" "IPR009721:O-acyltransferase WSD1, C-terminal" CG33120 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0042094 Adk3 Adenylate kinase 3 http://flybase.org/reports/FBgn0042094 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850, InterPro:IPR006259 nucleoside triphosphate adenylate kinase activity ; GO:0046899 | inferred from sequence or structural similarity with UniProtKB:P54819 adenylate kinase activity ; GO:0004017 | inferred from direct assay" ADP biosynthetic process ; GO:0006172 | inferred from sequence or structural similarity with UniProtKB:Q9UIJ7 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q9UIJ7 mitochondrion ; GO:0005739 | inferred from direct assay "DAK3, bs12h03.y1, AK3, CG6612, Adk3, Dak3" "IPR000850:Adenylate kinase/UMP-CMP kinase, IPR006259:Adenylate kinase subfamily, IPR007862:Adenylate kinase, active site lid domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033690:Adenylate kinase, conserved site, IPR028586:Adenylate kinase 3/4, mitochondrial" CG6612 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-199m3.4, Drer\ak8, Drer\ak3, Drer\ak7a, Drer\ak7b, Drer\ak4, Drer\ak2" "Scer\ADK1, Scer\ADK2" Cele\ZK673.2 "Xtro\ak8, Xtro\ak3, Xtro\ak9, Xtro\ak4, Xtro\ak7, Xtro\ak2" "Mmus\Ak7, Mmus\Ak4, Mmus\Ak3, Mmus\Ak2, Mmus\Ak8" "Hsap\AK4, Hsap\AK3, Hsap\AK8, Hsap\AK7, Hsap\AK9, Hsap\AK2" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC16075 K -0.061362466 -0.066519469 0.642398619 0.525573035 1.125668306 2.045279065 FBgn0013987 MAPk-Ak2 MAP kinase activated protein-kinase-2 http://flybase.org/reports/FBgn0013987 FBgn0029802 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement calmodulin binding ; GO:0005516 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN001553005 calcium-dependent protein serine/threonine kinase activity ; GO:0009931 | inferred from biological aspect of ancestor with PANTHER:PTN000681419" protein autophosphorylation ; GO:0046777 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of cell size ; GO:0045793 | inferred from genetic interaction with gig protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:6887 peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 regulation of JNK cascade ; GO:0046328 | inferred from genetic interaction with bsk inferred from genetic interaction with Mkk4 inferred from genetic interaction with Tak1 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype response to salt stress ; GO:0009651 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001553005 cell adhesion ; GO:0007155 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:6887 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6887 "MAPKAP, CG3086, DmMAPKAPK-2, MAPk-Ak2, MK2, MAPKAPK-2, dMK2" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR027442:MAP kinase activated protein kinase, C-terminal domain" CG3086 11-Aug-17 DroID_v2017_08 "Drer\mapkapk3, Drer\mapkapk2a, Drer\mapkapk2b, Drer\mapkapk5" "Scer\RCK1, Scer\RCK2" "Cele\mak-2, Cele\mak-1" "Xtro\mapkapk3, Xtro\mapkapk5, Xtro\mapkapk2" "Mmus\Mapkapk5, Mmus\Mapkapk2, Mmus\Mapkapk3" "Hsap\MAPKAPK2, Hsap\MAPKAPK5, Hsap\MAPKAPK3" " embryonic stage -- adult stage , oogenesis stage && adult stage | female , embryonic stage | early " ovary

"viable,partially lethal - majority live,nutrition conditional,melanotic mass phenotype" "embryonic/larval hindgut,posterior,nutrition conditional" FBgn0019698 l(2)k03111 lethal (2) k03111 http://flybase.net/reports/FBgn0019698.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0002045 l(2)37Di lethal (2) 37Di http://flybase.org/reports/FBgn0002045 - gene - - - "E103, l(2)E103, l(2)37Di" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051021 CG31021 - http://flybase.org/reports/FBgn0051021 protein_coding_gene "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR013547 endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG9708, CG31021" "IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG31021 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\zgc:158254, Drer\p4ha1a, Drer\p4htm, Drer\p4ha3, Drer\zgc:152670" - "Cele\phy-4, Cele\phy-2, Cele\dpy-18, Cele\C14E2.4, Cele\Y43F8B.19, Cele\phy-3" "Xtro\p4ha2, Xtro\p4ha3, Xtro\p4ha1" "Mmus\P4ha3, Mmus\P4ha2, Mmus\P4htm, Mmus\P4ha1" "Hsap\P4HA2, Hsap\P4HA3, Hsap\P4HTM, Hsap\P4HA1" viable FBgn0029154 Menl-1 Malic enzyme like-1 http://flybase.org/reports/FBgn0029154 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NAD+) activity ; GO:0004471 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302, InterPro:IPR015884 malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:0004473 | inferred from biological aspect of ancestor with PANTHER:PTN000601052" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302, InterPro:IPR015884 pyruvate metabolic process ; GO:0006090 | inferred from biological aspect of ancestor with PANTHER:PTN000601050 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000601050" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001157886 "CG30097, CG7964, Menl-1" "IPR001891:Malic oxidoreductase, IPR012301:Malic enzyme, N-terminal domain, IPR012302:Malic enzyme, NAD-binding, IPR015884:Malic enzyme, conserved site, IPR016040:NAD(P)-binding domain" CG7964 11-Aug-17 DroID_v2017_08 "Drer\me1, Drer\me3, Drer\me2, Drer\LOC101882012" Scer\MAE1 Cele\men-1 "Xtro\me3, Xtro\me2" "Mmus\Me3, Mmus\Me2, Mmus\Me1" "Hsap\ME1, Hsap\ME3, Hsap\ME2" DRSC07470 I 1.812401681 0.496558877 0.116615905 -0.227669372 0.531992361 -1.302536282 FBgn0010831 l(3)04063 lethal (3) 04063 http://flybase.org/reports/FBgn0010831 - gene - - - l(3)04063 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020842 l(2)BV "Blacksburg, VA" http://flybase.org/reports/FBgn0020842 - gene - - - l(2)BV - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035666 Jon65Aii Jonah 65Aii http://flybase.org/reports/FBgn0035666 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG6580, Jon65A, SP153, Jon65Aii" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG6580 11-Aug-17 DroID_v2017_08 - - - - "Mmus\C1s1, Mmus\C1s2" - viable FBgn0028408 Drep2 DNA fragmentation factor-related protein 2 http://flybase.org/reports/FBgn0028408 protein_coding_gene nuclease activity ; GO:0004518 | NOT inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of neuron death ; GO:1901215 | inferred from genetic interaction with Fmr1 regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000959605 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003508 postsynaptic membrane ; GO:0045211 | inferred from direct assay synaptic membrane ; GO:0097060 | inferred from direct assay "drep2, CG1975, anon-WO0118547.168, anon-WO0118547.162, Rep2, Drep-2, Drep2, DREP-2, rep2" IPR003508:CIDE-N domain CG1975 11-Aug-17 DroID_v2017_08 "Drer\cideb, Drer\cidea, Drer\cidec, Drer\dffa" - - "Xtro\cidea, Xtro\cidec" "Mmus\Cideb, Mmus\Cidec, Mmus\Dffa, Mmus\Cidea" "Hsap\CIDEA, Hsap\CIDEC, Hsap\DFFA, Hsap\CIDEB" "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0262417 mir-316 mir-316 stem loop http://flybase.org/reports/FBgn0262417 miRNA_gene - - - "miR-316, dme-mir-316, mir-316, MIR-316, CR42965, Mir-316, CR33620, dme-miR-316" - CR42965 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing margin,wing vein" FBgn0001501 l(1)10Cd lethal (1) 10Cd http://flybase.org/reports/FBgn0001501 - gene - - - l(1)10Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033308 CG8736 - http://flybase.org/reports/FBgn0033308 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR033778 - - "BcDNA:RH08259, CG8736" IPR033778:Cuticle protein CPCFC CG8736 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027338 Kap-alpha3 karyopherin alpha3 http://flybase.org/reports/FBgn0027338 "FBgn0024888, FBgn0026235, FBgn0028164" protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A Notch binding ; GO:0005112 | inferred from direct assay mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 response to UV ; GO:0009411 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 "imp alpha3, Imp alpha-3, imp-alpha3, dKap-alpha3, Kap alpha3, 0335/13, Kap-alpha3, l(3)S033513, imp-a3, CG9423, impalpha3, IMPalpha3, Kpna3, Kapalpha3, Dalpha3, Kap-?3, KAP-ALPHA3, dimpalpha3, Imp-alpha3, alphaKap3, kpn-alpha3, Kpn-alpha3" "IPR000225:Armadillo, IPR002652:Importin-alpha, importin-beta-binding domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024931:Importin subunit alpha, IPR032413:Atypical Arm repeat" CG9423 11-Aug-17 DroID_v2017_08 "Drer\spag6, Drer\kpna5, Drer\kpna4, Drer\kpna1, Drer\kpna7, Drer\kpna3, Drer\kpna6" Scer\SRP1 "Cele\ima-3, Cele\ima-1" "Xtro\kpna6, Xtro\kpna1, Xtro\kpna4, Xtro\kpna7, Xtro\spag6, Xtro\armc3, Xtro\kpna3, Xtro\kpna2" "Mmus\Kpna3, Mmus\Kpna4, Mmus\Spag6, Mmus\Kpna6, Mmus\Kpna7, Mmus\Kpna1, Mmus\Spag6l, Mmus\Kpna2" "Hsap\KPNA3, Hsap\KPNA5, Hsap\SPAG6, Hsap\KPNA7, Hsap\KPNA1, Hsap\KPNA6, Hsap\KPNA2, Hsap\KPNA4" embryonic stage -- adult stage "viable,fertile,lethal,female,lethal - all die before end of larval stage,some die during larval stage,wild-type,phototaxis defective,somatic clone,visible,heat sensitive,partially lethal - majority die,neuroanatomy defective" "eye,somatic clone,ommatidium,interommatidial bristle,rhabdomere,photoreceptor cell R7,tormogen cell,tergite,mesothoracic tergum" FBgn0085294 CG34265 - http://flybase.org/reports/FBgn0085294 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34265 - CG34265 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000070 Alu Alula http://flybase.org/reports/FBgn0000070 - gene - - - Alu - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,viable" "alula,wing" FBgn0004228 mex1 midgut expression 1 http://flybase.org/reports/FBgn0004228 - protein_coding_gene - - - "CG7936, mex1" - CG7936 11-Aug-17 DroID_v2017_08 - Scer\ZRG17 - - - Hsap\AP3B1 " embryonic stage | stage 12 , embryonic stage | stage >=12 , embryonic stage | stage >=9 , embryonic stage | stage >=14 , adult stage " " anterior midgut proper primordium

, posterior midgut proper primordium

, embryonic/larval midgut

" "viable,fertile" FBgn0013495 l(1)HA6 lethal (1) HA6 http://flybase.org/reports/FBgn0013495 - gene - - - "HA6, l(1)HA6" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010414 SerT Serotonin transporter http://flybase.org/reports/FBgn0010414 FBgn0011835 protein_coding_gene monoamine transmembrane transporter activity ; GO:0008504 | inferred from direct assay serotonin transmembrane transporter activity ; GO:0015222 | inferred from direct assay cation channel activity ; GO:0005261 | inferred from direct assay dopamine:sodium symporter activity ; GO:0005330 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 serotonin uptake ; GO:0051610 | inferred from direct assay dopamine uptake involved in synaptic transmission ; GO:0051583 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 serotonin transport ; GO:0006837 | inferred from direct assay monoamine transport ; GO:0015844 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype axon ; GO:0030424 | inferred from direct assay axon terminus ; GO:0043679 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:11050 "dSERT, SERT, dSerT, dSERT1, dSert, Sert, CG4545, SerT, DmSERT, DmSerT, dsert, serT, dmSERT" IPR000175:Sodium:neurotransmitter symporter CG4545 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-132b12.1, Drer\slc6a13l, Drer\slc6a1a, Drer\slc6a6a, Drer\slc6a2, Drer\slc6a13, Drer\slc6a13, Drer\slc6a19a.1, Drer\slc6a1b, Drer\slc6a19b, Drer\slc6a1l, Drer\slc6a19a.2, Drer\si:ch211-132b12.6, Drer\slc6a4a, Drer\slc6a11a, Drer\slc6a4b, Drer\slc6a5, Drer\si:ch211-132b12.2, Drer\slc6a14, Drer\slc6a15, Drer\slc6a8, Drer\slc6a16b, Drer\si:ch211-117c9.5, Drer\slc6a17, Drer\slc6a18, Drer\slc6a6b, Drer\slc6a9, Drer\slc6a16a, Drer\zgc:158225" - "Cele\mod-5, Cele\snf-6, Cele\dat-1, Cele\snf-3, Cele\snf-10, Cele\snf-11" "Xtro\slc6a17, Xtro\slc6a14.2, Xtro\slc6a9, Xtro\slc6a1, Xtro\slc6a8, Xtro\slc6a13, Xtro\slc6a5, Xtro\LOC100127682, Xtro\slc6a3, Xtro\slc6a6, Xtro\slc6a19, Xtro\slc6a15, Xtro\slc6a12, Xtro\slc6a7, Xtro\slc6a4, Xtro\slc6a16, Xtro\slc6a2" "Mmus\Slc6a4, Mmus\Slc6a6, Mmus\Slc6a12, Mmus\Slc6a20a, Mmus\Slc6a19, Mmus\Slc6a18, Mmus\Slc6a2, Mmus\Slc6a21, Mmus\Slc6a9, Mmus\Slc6a5, Mmus\Slc6a8, Mmus\Slc6a20b, Mmus\Slc6a7, Mmus\Slc6a17, Mmus\Slc6a13, Mmus\Slc6a11, Mmus\Slc6a14, Mmus\Slc6a1, Mmus\Slc6a15, Mmus\Slc6a3, Mmus\Slc6a16" "Hsap\SLC6A1, Hsap\SLC6A19, Hsap\SLC6A11, Hsap\SLC6A7, Hsap\SLC6A8, Hsap\SLC6A14, Hsap\SLC6A9, Hsap\SLC6A6, Hsap\SLC6A20, Hsap\SLC6A13, Hsap\SLC6A12, Hsap\SLC6A16, Hsap\SLC6A5, Hsap\SLC6A15, Hsap\SLC6A3, Hsap\SLC6A2, Hsap\SLC6A4, Hsap\SLC6A17, Hsap\SLC6A18" " larval stage , adult stage , embryonic stage | stage 15-17 " " larval central nervous system | restricted

, adult head

, embryonic central nervous system | restricted

" viable DRSC04655 I 0.893348037 -2.124372974 0.535584996 0.760108681 0.314793031 0.662334174 FBgn0038690 CG11703 - http://flybase.org/reports/FBgn0038690 protein_coding_gene - potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR000402 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR000402 sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred from electronic annotation with InterPro:IPR000402 "JYbeta2, anon-WO0140519.49, CG11703" IPR000402:Sodium/potassium-transporting ATPase subunit beta CG11703 11-Aug-17 DroID_v2017_08 "Drer\atp1b2a, Drer\atp1b1b, Drer\atp1b2b, Drer\atp1b3b, Drer\atp1b3a, Drer\atp1b4, Drer\atp1b1a" - "Cele\nkb-2, Cele\nkb-1, Cele\nkb-3" "Xtro\atp1b1, Xtro\atp1b3, Xtro\atp1b4, Xtro\atp1b2, Xtro\atp4b" "Mmus\Atp1b1, Mmus\Atp1b3, Mmus\Atp1b2, Mmus\Atp4b, Mmus\Atp1b4" "Hsap\ATP1B1, Hsap\ATP1B4, Hsap\ATP1B3, Hsap\ATP4B, Hsap\ATP1B2" viable FBgn0000688 flrdL flight reduced L http://flybase.org/reports/FBgn0000688 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdL - - 11-Aug-17 DroID_v2017_08 - - - - - - "hypoactive,flight defective" FBgn0062694 EP1236 EP1236 http://flybase.org/reports/FBgn0062694 gene - - - "EP(2)1236, EP1236" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262606 CR43132 - http://flybase.org/reports/FBgn0262606 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43132, CG43132, lincRNA.1005, mdcds_55191" - CR43132 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065433 l(2)SH1482 lethal (2) SH1482 http://flybase.org/reports/FBgn0065433 gene - - - "l(2)SH1482, l(2)SH2 1482" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001438 l(1)7Bf lethal (1) 7Bf http://flybase.org/reports/FBgn0001438 - gene - - - "l(1)GF320, l(1)7Bf" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004367 mei-41 meiotic 41 http://flybase.org/reports/FBgn0004367 "FBgn0002708, FBgn0002880" protein_coding_gene protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:882 protein kinase activity ; GO:0004672 | non-traceable author statement "response to radiation ; GO:0009314 | traceable author statement imaginal disc development ; GO:0007444 | traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from sequence or structural similarity with HGNC:882 regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype inferred from genetic interaction with dup cellularization ; GO:0007349 | traceable author statement double-strand break repair via synthesis-dependent strand annealing ; GO:0045003 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype response to caffeine ; GO:0031000 | inferred from genetic interaction with MAGE actin filament organization ; GO:0007015 | inferred from mutant phenotype phosphorylation ; GO:0016310 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from genetic interaction with tefu, nbs mitotic DNA replication checkpoint ; GO:0033314 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype inferred from genetic interaction with nbs DNA damage checkpoint ; GO:0000077 | traceable author statement DNA replication checkpoint ; GO:0000076 | inferred from mutant phenotype double-strand break repair via single-strand annealing ; GO:0045002 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement oocyte fate determination ; GO:0030716 | inferred from mutant phenotype regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | traceable author statement meiotic nuclear division ; GO:0007126 | traceable author statement mitotic cell cycle checkpoint ; GO:0007093 | traceable author statement meiotic DNA double-strand break processing ; GO:0000706 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement chromosome condensation ; GO:0030261 | inferred from genetic interaction with PR-Set7 protein phosphorylation ; GO:0006468 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:882 "mei-41, ATR, CG4252, meiP41, mus104, mei41, mus103, MEI41/FRP1, Mei-41, MEI41, mus-104, mus(1)104, fs(1)M37, mus(1)103, mus-103, atr, mei-195, DmATR, Mei-41/DATR, 4252, Dmmei41" "IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR003151:PIK-related kinase, FAT, IPR003152:FATC domain, IPR011009:Protein kinase-like domain, IPR012993:UME domain, IPR014009:PIK-related kinase, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR011990:Tetratricopeptide-like helical domain" CG4252 11-Aug-17 DroID_v2017_08 Drer\atr "Scer\MEC1, Scer\TEL1" "Cele\atl-1, Cele\smg-1, Cele\atm-1" Xtro\atr Mmus\Atr Hsap\ATR oogenesis stage && adult stage | female ovary

"female sterile,partially,chemical sensitive,viable,semidominant,heat sensitive,recessive,radiation sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,meiotic cell cycle defective,female fertile,wild-type,lethal,rescuable maternal effect,female semi-sterile,maternal effect,DNA repair defective,dominant,mitotic cell cycle defective,radiation resistant,reduced,decreased cell death,increased cell death" "egg,maternal effect,mitotic interphase | embryonic cycle 12 | maternal effect,mitotic interphase | embryonic cycle 13 | maternal effect,blastoderm embryo,cycle 13 embryo,cycle 14 embryo,spindle,neuroblast,presumptive oocyte,mitosis & nuclear chromosome,eye disc,conditional,morphogenetic furrow,metaphase & condensed nuclear chromosome | conditional qualifier,wing disc,SO0000340chromosome | larval stage" FBgn0065102 snmRNA:184 small non-messenger RNA 184 http://flybase.org/reports/FBgn0065102 non_protein_coding_gene - - - "Dm-184, CR33916, snmRNA:184" - CR33916 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011007 l(3)s1696 lethal (3) s1696 http://flybase.org/reports/FBgn0011007 - gene - - - l(3)s1696 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0037723 SpdS Spermidine Synthase http://flybase.org/reports/FBgn0037723 protein_coding_gene spermidine synthase activity ; GO:0004766 | inferred from biological aspect of ancestor with PANTHER:PTN000900703 spermidine biosynthetic process ; GO:0008295 | inferred from biological aspect of ancestor with PANTHER:PTN000900703 cellular_component ; GO:0005575 | no biological data available "CG8327, SpdS, Spds" "IPR030373:Polyamine biosynthesis domain, conserved site, IPR030374:Polyamine biosynthesis domain, IPR001045:Spermidine/spermine synthases, IPR030668:Spermidine/spermine synthase, eukaryotes, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG8327 11-Aug-17 DroID_v2017_08 "Drer\srm, Drer\sms" "Scer\SPE4, Scer\SPE3" Cele\spds-1 "Xtro\sms, Xtro\srm" "Mmus\Sms, Mmus\Srm" "Hsap\SMS, Hsap\SRM" "long lived,viable" FBgn0058412 CG40412 - http://flybase.org/reports/FBgn0058412 protein_coding_gene - - - CG40412 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082981 snoRNA:Psi28S-2949 snoRNA:Psi28S-2949 http://flybase.org/reports/FBgn0082981 snoRNA_gene - - - "snoRNA:Psi28S-2949, psi28S-2949, Psi 28S-2949, CR34525, Psi28S-2949" - CR34525 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032648 CG15144 - http://flybase.org/reports/FBgn0032648 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15144 "IPR032840:MAATS1 domain, IPR026720:Protein MAATS1" CG15144 11-Aug-17 DroID_v2017_08 Drer\maats1 - - Xtro\maats1 Mmus\Maats1 Hsap\MAATS1 viable FBgn0267257 CR45693 - http://flybase.org/reports/FBgn0267257 non_protein_coding_gene - - - CR45693 - CR45693 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259388 C545 - http://flybase.org/reports/FBgn0259388 gene - - - C545 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0004507 GlyP Glycogen phosphorylase http://flybase.org/reports/FBgn0004507 "FBgn0027859, FBgn0063790" protein_coding_gene glycogen phosphorylase activity ; GO:0008184 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay glycogen phosphorylase activity ; GO:0008184 | inferred from mutant phenotype pyridoxal phosphate binding ; GO:0030170 | inferred from direct assay negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype positive regulation of glycogen catabolic process ; GO:0045819 | inferred from mutant phenotype glycogen catabolic process ; GO:0005980 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000157685 "GlyP, GP, l(2)k07918, Glp1, DGPH, CG7254, BcDNA:LD24485, anon-WO0257455.33, Glyp" "IPR000811:Glycosyl transferase, family 35, IPR011833:Glycogen/starch/alpha-glucan phosphorylase" CG7254 11-Aug-17 DroID_v2017_08 "Drer\pygma, Drer\pygb, Drer\pygl, Drer\pygmb" Scer\GPH1 Cele\T22F3.3 "Xtro\pygl, Xtro\pygm" "Mmus\Pygb, Mmus\Pygm, Mmus\Pygl" "Hsap\PYGM, Hsap\PYGB, Hsap\PYGL" " embryonic stage | 0-2hr , embryonic stage -- adult stage " "long lived,RU486 conditional,viable,reduced" FBgn0060824 l(3)S051701b lethal (3) S051701b http://flybase.org/reports/FBgn0060824 gene - - - "0517/01, l(3)S051701b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004411 het-rep3 heterochromatic repeat 3 http://flybase.org/reports/FBgn0004411 - repeat_region - - - het-rep3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051296 CG31296 - http://flybase.org/reports/FBgn0051296 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "NEST:bs01d08, CG31296" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG31296 11-Aug-17 DroID_v2017_08 "Drer\crispld1a, Drer\pi15a, Drer\r3hdml, Drer\glipr2l, Drer\glipr1b, Drer\crispld1b, Drer\glipr2, Drer\crispld2, Drer\LOC100536500, Drer\pi15b" "Scer\PRY1, Scer\PRY3, Scer\PRY2" "Cele\scl-10, Cele\scl-15, Cele\scl-19, Cele\vap-2, Cele\scl-5, Cele\scl-17, Cele\scl-23, Cele\scl-13, Cele\scl-18, Cele\scl-14, Cele\scl-20, Cele\scl-7, Cele\scl-3, Cele\scl-12, Cele\scl-11, Cele\scl-8, Cele\scl-6, Cele\scl-9, Cele\scl-21, Cele\scl-2, Cele\scl-1" "Xtro\crisp2, Xtro\glipr2, Xtro\crispld2, Xtro\MGC108118, Xtro\crisp3, Xtro\crisp1, Xtro\r3hdml" "Mmus\Crisp1, Mmus\Glipr1, Mmus\Crisp3, Mmus\Clec18a, Mmus\Glipr2, Mmus\Crisp2, Mmus\Pi15, Mmus\Glipr1l1, Mmus\Crispld2, Mmus\Crispld1, Mmus\R3hdml, Mmus\Glipr1l2, Mmus\Crisp4, Mmus\Pi16" "Hsap\CRISP1, Hsap\CRISPLD1, Hsap\CLEC18B, Hsap\CLEC18C, Hsap\PI16, Hsap\GLIPR1L2, Hsap\GLIPR1, Hsap\GLIPR2, Hsap\CRISP2, Hsap\GLIPR1L1, Hsap\CRISPLD2, Hsap\PI15, Hsap\CLEC18A, Hsap\R3HDML" viable FBgn0004061 bip bipolar oocyte http://flybase.org/reports/FBgn0004061 - gene molecular_function ; GO:0003674 | no biological data available oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "bip, BiP" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "dorsal appendage,egg chamber,nurse cell,stage S14B oocyte,oocyte" FBgn0002555 lm limited http://flybase.org/reports/FBgn0002555 - gene - - - lm - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female sterile" "sternite,macrochaeta" FBgn0022963 splinter splinter http://flybase.org/reports/FBgn0022963 - gene - - - splinter - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065354 l(2)SH1775 lethal (2) SH1775 http://flybase.org/reports/FBgn0065354 gene - - - "l(2)SH1775, l(2)SH2 1775" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033501 CG12911 - http://flybase.org/reports/FBgn0033501 protein_coding_gene - - - CG12911 - CG12911 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0037261 CG9775 - http://flybase.org/reports/FBgn0037261 protein_coding_gene - - - CG9775 "IPR025715:Chromatin target of PRMT1 protein, C-terminal" CG9775 11-Aug-17 DroID_v2017_08 Drer\chtopa - - Xtro\chtop Mmus\Chtop Hsap\CHTOP viable DRSC22667 IE 2.748252541 -0.516737251 3.175856949 2.073436003 0.028200923 -0.726305087 FBgn0052023 CG32023 - http://flybase.org/reports/FBgn0052023 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32023 - CG32023 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025506 l(3)72Fa lethal (3) 72Fa http://flybase.org/reports/FBgn0025506 - gene - - - l(3)72Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of first instar larval stage,some die during first instar larval stage" FBgn0065716 l(2)SH0578 lethal (2) SH0578 http://flybase.org/reports/FBgn0065716 gene - - - "l(2)SH0578, l(2)SH2 0578" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005048 exr extra venation http://flybase.org/reports/FBgn0005048 - gene - - - exr - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile,recessive,male fertile,visible" "eye,wing vein,wing" FBgn0024628 l(2)k15306 lethal (2) k15306 http://flybase.org/reports/FBgn0024628 - gene - - - "153/6, l(2)k15306" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0267801 CR46126 - http://flybase.org/reports/FBgn0267801 non_protein_coding_gene - - - CR46126 - CR46126 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013624 l(3)neo15 lethal (3) neo15 http://flybase.org/reports/FBgn0013624 - gene - - - l(3)neo15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0034724 babos babos http://flybase.org/reports/FBgn0034724 protein_coding_gene - regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype perivitelline space ; GO:0098595 | inferred from direct assay "CT12183, babos, CG3624" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013151:Immunoglobulin" CG3624 11-Aug-17 DroID_v2017_08 "Drer\kirrelb, Drer\kirrel3l, Drer\dscama, Drer\si:ch1073-459j12.1, Drer\lrit3a, Drer\itgb4, Drer\igsf9bb, Drer\paplna, Drer\sdk1a, Drer\kirrel3a, Drer\sdk1b, Drer\igsf9a, Drer\kirrel3b, Drer\lrit1b, Drer\kirrela, Drer\ncam1b, Drer\lrit1a, Drer\ush2a, Drer\lrit3b" - - "Xtro\lrit3, Xtro\igsf9b, Xtro\papln, Xtro\kirrel2" "Mmus\Kirrel3, Mmus\Ptprq, Mmus\Kirrel, Mmus\Lrit1, Mmus\Lrit3, Mmus\Papln, Mmus\Igsf9b, Mmus\Sdk1, Mmus\Kirrel2" "Hsap\KIRREL, Hsap\KIRREL2, Hsap\PAPLN, Hsap\USH2A, Hsap\LRIT1, Hsap\LRIT3, Hsap\SDK1, Hsap\IGSF9B, Hsap\KIRREL3" "neuroanatomy defective,viable,partially lethal - majority die,some die during pupal stage" "embryonic/larval salivary gland,embryonic/larval hemocyte | third instar larval stage,dendrite | third instar larval stage,LNv neuron" FBgn0031952 cdc14 cell division cycle 14 http://flybase.org/reports/FBgn0031952 protein_coding_gene protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 protein tyrosine phosphatase activity ; GO:0004725 | inferred from biological aspect of ancestor with PANTHER:PTN000596945 protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with HGNC:1719 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with HGNC:1719 mitotic cell cycle arrest ; GO:0071850 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 peptidyl-tyrosine dephosphorylation ; GO:0035335 | inferred from sequence or structural similarity with HGNC:1719 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 mitotic spindle midzone assembly ; GO:0051256 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 regulation of exit from mitosis ; GO:0007096 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 protein dephosphorylation ; GO:0006470 | non-traceable author statement spindle pole ; GO:0000922 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000596947 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000596945 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:1719 mitotic spindle ; GO:0072686 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 "CDC14, cdc14, CG7134, CDC-14, Cdc14" "IPR000387:Tyrosine specific protein phosphatases domain, IPR000340:Dual specificity phosphatase, catalytic domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR029260:Dual specificity/tyrosine protein phosphatase, N-terminal, IPR029021:Protein-tyrosine phosphatase-like, IPR026070:Tyrosine-protein phosphatase CDC14, IPR003595:Protein-tyrosine phosphatase, catalytic, IPR020422:Dual specificity protein phosphatase domain" CG7134 11-Aug-17 DroID_v2017_08 "Drer\cdkn3, Drer\cdc14b, Drer\cdc14aa, Drer\dusp23b, Drer\cdc14ab, Drer\dusp23a, Drer\ptpdc1b, Drer\ptpdc1a" Scer\CDC14 Cele\cdc-14 "Xtro\dusp23, Xtro\cdc14a, Xtro\cdc14b, Xtro\ptpdc1" "Mmus\Dusp23, Mmus\Cdc14a, Mmus\Ptpdc1, Mmus\Cdkn3, Mmus\Cdc14b" "Hsap\CDC14A, Hsap\PTPDC1, Hsap\CDKN3, Hsap\CDC14B, Hsap\DUSP23" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval hemocyte | third instar larval stage FBgn0010902 l(3)06803 lethal (3) 06803 http://flybase.org/reports/FBgn0010902 - gene - - - l(3)06803 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0262592 CG43127 - http://flybase.org/reports/FBgn0262592 protein_coding_gene - - - "CG43127, CG42519, CG34237, CG42520" - CG43127 11-Aug-17 DroID_v2017_08 "Drer\unc93b1, Drer\unc93a" - - "Xtro\unc93a, Xtro\unc93b1" "Mmus\Gm9992, Mmus\Unc93a, Mmus\Unc93b1" "Hsap\UNC93A, Hsap\UNC93B1" FBgn0265866 CR44655 - http://flybase.org/reports/FBgn0265866 non_protein_coding_gene - - - "lincRNA.990, CR44655" - CR44655 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033324 CG14744 - http://flybase.org/reports/FBgn0033324 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004837 CG14744 IPR004837:Sodium/calcium exchanger membrane region CG14744 11-Aug-17 DroID_v2017_08 "Drer\slc24a4b, Drer\slc8b1" "Scer\ECM27, Scer\YDL206W" "Cele\ncx-7, Cele\ncx-10, Cele\ncx-8, Cele\ncx-9, Cele\ncx-6" Xtro\slc8b1 "Mmus\Slc8b1, Mmus\Slc24a3, Mmus\Slc24a4" "Hsap\SLC24A3, Hsap\SLC8B1, Hsap\SLC24A4" viable FBgn0000970 Fs(2)Etr Female sterile (2) Etre http://flybase.org/reports/FBgn0000970 - gene - - - "Etre, Fs(2)Sz4, Fs(2)Etr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile soma-dependent,dominant" "dorsal appendage,egg,chorion" FBgn0033058 CCHa2-R CCHamide-2 receptor http://flybase.org/reports/FBgn0033058 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from direct assay neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "anon-WO0131005.23, CG14594, CG14593, CCHa2-R, CCHa2r" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001556:Bombesin receptor-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG14593 11-Aug-17 DroID_v2017_08 "Drer\ednrab, Drer\gpr37a, Drer\gpr37l1a, Drer\ednrbb, Drer\nmbr, Drer\gpr37b, Drer\ednrba, Drer\si:ch211-119o8.4, Drer\gpr37l1b, Drer\grpr, Drer\ednraa" - Cele\npr-4 "Xtro\grpr, Xtro\gpr37, Xtro\ednrb2, Xtro\brs3, Xtro\ednrb, Xtro\ednra" "Mmus\Ednra, Mmus\Ednrb, Mmus\Brs3, Mmus\Nmbr, Mmus\Gpr37l1, Mmus\Gpr37, Mmus\Grpr" "Hsap\EDNRB, Hsap\GRPR, Hsap\EDNRA, Hsap\BRS3, Hsap\NMBR, Hsap\GPR37L1, Hsap\GPR37" viable DRSC04870 EK -0.398587106 0.732574989 -0.173721557 2.727721214 2.091305807 0.151875494 FBgn0053453 CG33453 - http://flybase.org/reports/FBgn0053453 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33453 IPR010512:Protein of unknown function DUF1091 CG33453 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003708 tipC temperature-induced paralytic C http://flybase.org/reports/FBgn0003708 - gene - - - tipC - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,heat sensitive" FBgn0032378 CycY Cyclin Y http://flybase.org/reports/FBgn0032378 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR012399 regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | inferred from electronic annotation with InterPro:IPR012399 developmental growth ; GO:0048589 | inferred from mutant phenotype - "i182, anon-WO0118547.165, Dcyclin Y, CycY, CG14939" "IPR006671:Cyclin, N-terminal, IPR012399:Cyclin Y, IPR013763:Cyclin-like" CG14939 11-Aug-17 DroID_v2017_08 "Drer\ccnyl1, Drer\ccny" "Scer\LAM1, Scer\PHO80, Scer\SIP3" Cele\cyy-1 "Xtro\ccnyl1, Xtro\ccny" "Mmus\Ccnyl1, Mmus\Ccny" "Hsap\AGAP4, Hsap\CCNY, Hsap\CCNYL1" viable FBgn0266915 CR45375 - http://flybase.org/reports/FBgn0266915 non_protein_coding_gene - - - CR45375 - CR45375 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003051 Pdr Purpleoider http://flybase.org/reports/FBgn0003051 - gene - - - Pdr - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0267352 BG01272 - http://flybase.org/reports/FBgn0267352 gene - - - BG01272 - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,male,heat stress response defective,female,starvation stress response defective" macrochaeta FBgn0038125 CG8141 - http://flybase.org/reports/FBgn0038125 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-like protein conjugating enzyme binding ; GO:0044390 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 zinc ion binding ; GO:0008270 | inferred from sequence model ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 Derlin-1 retrotranslocation complex ; GO:0036513 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 "BcDNA:AT26376, CG8141" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8141 11-Aug-17 DroID_v2017_08 "Drer\rnf5, Drer\rnf185" Scer\SLX8 Cele\rnf-5 "Xtro\rnf185, Xtro\rnf5" "Mmus\Rnf185, Mmus\Rnf5" "Hsap\RNF185, Hsap\RNF5" viable FBgn0001134 Grd Glycine receptor http://flybase.org/reports/FBgn0001134 - protein_coding_gene GABA-gated chloride ion channel activity ; GO:0022851 | inferred from direct assay extracellular-glycine-gated ion channel activity ; GO:0016933 | inferred from sequence or structural similarity GABA-A receptor activity ; GO:0004890 | inferred from direct assay cation channel activity ; GO:0005261 | inferred from direct assay ligand-gated ion channel activity ; GO:0015276 | inferred from sequence or structural similarity ligand-gated ion channel activity ; GO:0015276 | inferred from direct assay ion transport ; GO:0006811 | inferred from direct assay "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201 integral component of membrane ; GO:0016021 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity" "DmGABA(GRD), CG7446, GRD, Grd, CT22917" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG7446 11-Aug-17 DroID_v2017_08 "Drer\gabrp, Drer\gabrd, Drer\gabrg3, Drer\gabrr2b, Drer\gabrr3a, Drer\gabra3, Drer\glrbb, Drer\gabrb2, Drer\gabra1, Drer\glra3, Drer\si:dkey-155h10.3, Drer\LOC100001259, Drer\gabrb1, Drer\si:dkey-52k1.6, Drer\gabra5, Drer\LOC562831, Drer\gabrr2a, Drer\glra4a, Drer\zgc:110204, Drer\glra4b, Drer\gabrg2, Drer\gabrb3, Drer\gabrr1, Drer\glrba, Drer\LOC100330554, Drer\gabra6a, Drer\glra2, Drer\gabrb4, Drer\gabra6b" - "Cele\avr-14, Cele\ggr-1, Cele\gab-1, Cele\glc-2, Cele\glc-3, Cele\lgc-39, Cele\glc-4, Cele\lgc-44, Cele\lgc-41, Cele\lgc-42, Cele\lgc-38, Cele\lgc-40, Cele\unc-49, Cele\lgc-37, Cele\avr-15, Cele\lgc-36" "Xtro\gabrd, Xtro\gabrb3, Xtro\gabrr3, Xtro\gabra5, Xtro\glra2, Xtro\glrb, Xtro\glra3, Xtro\LOC100490720, Xtro\gabrp, Xtro\gabra6, Xtro\gabra3, Xtro\gabra2, Xtro\gabrg2, Xtro\glra1" "Mmus\Gabrg3, Mmus\Gabra4, Mmus\Glra2, Mmus\Glrb, Mmus\Gabrq, Mmus\Gabra1, Mmus\Gabrr2, Mmus\Gabrr3, Mmus\Gabrb3, Mmus\Gabra3, Mmus\Gabre, Mmus\Gabra2, Mmus\Gabrb1, Mmus\Gabrg1, Mmus\Gabrd, Mmus\Glra1, Mmus\Glra3, Mmus\Gabra5, Mmus\Glra4, Mmus\Gabrb2, Mmus\Gabra6, Mmus\Gabrr1, Mmus\Gabrg2, Mmus\Gabrp" "Hsap\GLRA2, Hsap\GABRA5, Hsap\GABRR1, Hsap\GLRA1, Hsap\GLRA4, Hsap\GABRB2, Hsap\GABRG2, Hsap\GABRB1, Hsap\GABRA3, Hsap\GABRG3, Hsap\GABRA2, Hsap\GABRG1, Hsap\GABRA1, Hsap\GABRD, Hsap\GABRR3, Hsap\GLRA3, Hsap\GLRB, Hsap\GABRE, Hsap\GABRR2, Hsap\GABRQ, Hsap\GABRP, Hsap\GABRB3, Hsap\GABRA4, Hsap\GABRA6" viable FBgn0044377 anon-AE003538.2 anon-AE003538.2 http://flybase.org/reports/FBgn0044377 gene - - - anon-AE003538.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040804 CG13453 - http://flybase.org/reports/FBgn0040804 protein_coding_gene - - - CG13453 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260386 mtg mind the gap http://flybase.org/reports/FBgn0260386 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 carbohydrate derivative binding ; GO:0097367 | inferred from direct assay chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 synapse assembly ; GO:0007416 | inferred from direct assay synaptic cleft ; GO:0043083 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "mtg, CG7549, 0849/10, l(3)S084910, l(3)S084910b, Mtg" "IPR002557:Chitin binding domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG7549 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - FBgn0002727 mfd myofibrillar defect http://flybase.org/reports/FBgn0002727 - gene - - - mfd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066317 29B70 29B70 http://flybase.org/reports/FBgn0066317 gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 29B70 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval mushroom body,somatic clone" FBgn0085764 CR40668 - http://flybase.org/reports/FBgn0085764 rRNA_gene - - - CR40668 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005444 l(1)v150 lethal (1) v150 http://flybase.org/reports/FBgn0005444 - gene - - - "l(1)150, l(1)v150" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022302 l(1)L60.6 lethal (1) L60.6 http://flybase.org/reports/FBgn0022302 - gene - - - "L60.6, l(1)L60.6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058370 CG40370 - http://flybase.org/reports/FBgn0058370 protein_coding_gene - - - CG40370 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265690 CR44497 - http://flybase.org/reports/FBgn0265690 non_protein_coding_gene - - - "lincRNA.113, CR44497" - CR44497 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082592 fiddler-crab fiddler-crab http://flybase.org/reports/FBgn0082592 gene - - - fiddler-crab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003748 Treh Trehalase http://flybase.org/reports/FBgn0003748 "FBgn0014436, FBgn0025313, FBgn0034584" protein_coding_gene "alpha,alpha-trehalase activity ; GO:0004555 | inferred from mutant phenotype trehalase activity ; GO:0015927 | inferred from mutant phenotype alpha,alpha-trehalase activity ; GO:0004555 | inferred from direct assay" neuronal stem cell population maintenance ; GO:0097150 | inferred from mutant phenotype trehalose catabolic process ; GO:0005993 | inferred from mutant phenotype trehalose metabolic process ; GO:0005991 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "TRE, 87D3T, Tre, TREH, anon-sts38, anon-EST:Posey159, ESTS:87D3T, CG9364, Treh, DmTre" "IPR018232:Glycoside hydrolase, family 37, conserved site, IPR001661:Glycoside hydrolase, family 37, IPR008928:Six-hairpin glycosidase-like" CG9364 11-Aug-17 DroID_v2017_08 Drer\treh "Scer\NTH2, Scer\NTH1" "Cele\tre-1, Cele\tre-4, Cele\tre-5, Cele\tre-3, Cele\tre-2" Xtro\treh Mmus\Treh Hsap\TREH "viable,fertile,visible,planar polarity defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0032523 CG16956 - http://flybase.org/reports/FBgn0032523 protein_coding_gene - - - CG16956 - CG16956 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0082930 snoRNA:Me28S-G2703b snoRNA:Me28S-G2703b http://flybase.org/reports/FBgn0082930 snoRNA_gene - - - "snoRNA:Me28S-G2703b, Me28S-Gm2703b, CR34540" - CR34540 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026342 Su(tor)2-113-31 Su(tor)2-113-31 http://flybase.org/reports/FBgn0026342 - gene - - - Su(tor)2-113-31 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037504 CG1142 - http://flybase.org/reports/FBgn0037504 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:24013 biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24013 CG1142 IPR014810:Fcf2 pre-rRNA processing CG1142 11-Aug-17 DroID_v2017_08 Drer\dnttip2 Scer\FCF2 Cele\Y49F6B.2 - Mmus\Dnttip2 Hsap\DNTTIP2 FBgn0025347 anon-11b anon-11b http://flybase.org/reports/FBgn0025347 - gene - - - anon-11b - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0087014 l(3)61Db-S lethal (3) 61Db of Saito http://flybase.org/reports/FBgn0087014 gene - - - "l(3)61Db-S, l(3)61Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004168 5-HT1A 5-hydroxytryptamine (serotonin) receptor 1A http://flybase.org/reports/FBgn0004168 - protein_coding_gene G-protein coupled serotonin receptor activity ; GO:0004993 | traceable author statement Gi/o-coupled serotonin receptor activity ; GO:0001586 | non-traceable author statement G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity neurotransmitter receptor activity ; GO:0030594 | inferred from biological aspect of ancestor with PANTHER:PTN000664111 G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from direct assay G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from sequence or structural similarity "phospholipase C-activating serotonin receptor signaling pathway ; GO:0007208 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype anesthesia-resistant memory ; GO:0007615 | inferred from direct assay adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | inferred from direct assay adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | traceable author statement serotonin receptor signaling pathway ; GO:0007210 | inferred from direct assay serotonin receptor signaling pathway ; GO:0007210 | inferred from sequence or structural similarity phospholipase C-activating serotonin receptor signaling pathway ; GO:0007208 | traceable author statement regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "CG16720, 5HT[[1ADro]], Dm5HTdro2A, 5HT-dro2A, 5-HT[[1ADro]], 5-HT-dro2A, DRO2A, 5htdro2a, 5-HT1ADro, 5HT1A, 5HT-drp[[2A]], 5HT-R2A, 5-HT1A, d5-HT1A, 5-HT[1A]Dro, 5-HT[[1A]], 5-HT[[1A]]DRO, HT1A, 5HT1a" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG16720 11-Aug-17 DroID_v2017_08 "Drer\or137-1, Drer\or137-5, Drer\si:dkeyp-3f10.11, Drer\htr5ab, Drer\or133-1, Drer\or137-8, Drer\or132-2, Drer\or137-2, Drer\or132-4, Drer\or132-3, Drer\or137-4, Drer\or137-3, Drer\or135-1, Drer\htr1d, Drer\or134-1, Drer\or132-5, Drer\htr1fb, Drer\htr1aa, Drer\si:dkeyp-3f10.12, Drer\si:dkeyp-3f10.14, Drer\htr1fa, Drer\htr5aa, Drer\si:dkey-92k1.9, Drer\htr1ab, Drer\or137-9, Drer\htr1e, Drer\or136-1, Drer\or132-1, Drer\or137-7, Drer\htr1b" - Cele\ser-4 "Xtro\htr5a, Xtro\htr1f, Xtro\htr1a" "Mmus\Htr5b, Mmus\Htr1d, Mmus\Htr1f, Mmus\Htr1a, Mmus\Htr1b, Mmus\Htr5a" "Hsap\HTR1F, Hsap\HTR1D, Hsap\HTR5A, Hsap\HTR1B, Hsap\HTR1E, Hsap\HTR1A" " embryonic stage | stage 16-17 , embryonic stage | stage 16,17 " " ventral midline

, embryonic central nervous system

, VUM neuron

" "starvation stress response defective,short lived,cold stress response defective,behavior defective,heat stress response defective,memory defective" FBgn0051563 CG31563 - http://flybase.org/reports/FBgn0051563 protein_coding_gene - - - CG31563 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of pupal stage,some die during pupal stage" DRSC21338 K -1.382546749 1.27048122 -0.867556727 -0.129577522 -0.757207174 -1.692280197 FBgn0039083 CG10177 - http://flybase.org/reports/FBgn0039083 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype signal transduction involved in mitotic DNA damage checkpoint ; GO:1902402 | inferred from biological aspect of ancestor with PANTHER:PTN002389494 Golgi organization ; GO:0007030 | inferred from mutant phenotype peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from biological aspect of ancestor with PANTHER:PTN002389494 negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN002389494 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN002389494 CG10177 "IPR000719:Protein kinase domain, IPR003533:Doublecortin domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG10177 11-Aug-17 DroID_v2017_08 "Drer\LOC100334396, Drer\trioa, Drer\camk1a, Drer\mylk4a, Drer\mylk3, Drer\triob, Drer\camk1b, Drer\dapk1, Drer\zgc:153952, Drer\si:ch211-27e6.1, Drer\chek1, Drer\stk17a, Drer\LOC101886687, Drer\mylk4b, Drer\camkva, Drer\uhmk1, Drer\camkvb, Drer\dapk3, Drer\capsla, Drer\camkvl, Drer\spegb, Drer\dclk2a, Drer\si:dkey-240h12.4, Drer\capslb, Drer\stk17b, Drer\dapk2a, Drer\dapk2b, Drer\camk1gb, Drer\camk4, Drer\camk1db, Drer\si:ch73-60h1.1, Drer\pskh1, Drer\camk1da, Drer\stk33, Drer\pnck, Drer\camk1ga, Drer\ttnb" "Scer\RCK2, Scer\TDA1, Scer\RCK1, Scer\CMK2, Scer\CMK1, Scer\MEK1, Scer\IRE1, Scer\IKS1, Scer\CHK1" "Cele\zyg-8, Cele\R02C2.1, Cele\zyg-1, Cele\T07F12.4" "Xtro\caps, Xtro\trio, Xtro\stk17a, Xtro\dapk3, Xtro\pskh1, Xtro\dclk2, Xtro\dapk1, Xtro\camk4, Xtro\mylk4, Xtro\pnck, Xtro\kalrn, Xtro\mylk3, Xtro\dcx, Xtro\camk1g, Xtro\pskh2, Xtro\camk1d, Xtro\capsl, Xtro\camkv, Xtro\dapk2, Xtro\camk1, Xtro\stk33" "Mmus\Mylk2, Mmus\Stk17b, Mmus\Camk4, Mmus\Dclk1, Mmus\Caps2, Mmus\Camk1g, Mmus\Obscn, Mmus\Speg, Mmus\Camk1, Mmus\Dapk1, Mmus\Capsl, Mmus\Stk33, Mmus\Dclk2, Mmus\Pnck, Mmus\Mylk4, Mmus\Pskh1, Mmus\Camk1d, Mmus\Trio, Mmus\Dapk3, Mmus\Uhmk1, Mmus\Dapk2, Mmus\Camkv, Mmus\Mylk3, Mmus\Dcx" "Hsap\DCLK1, Hsap\DAPK2, Hsap\OBSCN, Hsap\DAPK1, Hsap\MYLK3, Hsap\MYLK2, Hsap\CAMK1, Hsap\SPEG, Hsap\CAPS2, Hsap\DAPK3, Hsap\DCLK2, Hsap\CAPS, Hsap\STK17A, Hsap\UHMK1, Hsap\CAPSL, Hsap\CAMK1D, Hsap\PNCK, Hsap\CAMKV, Hsap\MYLK4, Hsap\STK17B, Hsap\PSKH2, Hsap\CAMK4, Hsap\STK33, Hsap\CAMK1G, Hsap\DCX, Hsap\TRIO, Hsap\PSKH1" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0003298 rud ruddle http://flybase.org/reports/FBgn0003298 - gene - - - rud - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,good,fertile,visible,recessive,eye color defective" pigment cell FBgn0065402 l(2)SH1602 lethal (2) SH1602 http://flybase.org/reports/FBgn0065402 gene - - - "l(2)SH1602, l(2)SH2 1602" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082909 60-16 60-16 http://flybase.org/reports/FBgn0082909 gene - - - 60-16 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023114 anon-10At anon-10At http://flybase.org/reports/FBgn0023114 - gene - - - "13, anon-10At" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028126 l(3)S057809a lethal (3) S057809a http://flybase.org/reports/FBgn0028126 gene - - - "0578/09, l(3)S057809, l(3)S057809a, l(3)s057809" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085528 CG40862 - http://flybase.org/reports/FBgn0085528 protein_coding_gene - - - CG40862 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259664 B0751 - http://flybase.org/reports/FBgn0259664 gene - - - B0751 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "submarginal cell,wing" FBgn0085834 CR42217 - http://flybase.org/reports/FBgn0085834 non_protein_coding_gene - - - CR42217 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259320 EP-M - http://flybase.org/reports/FBgn0259320 gene - - - EP-M - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0016767 anon-17Cd anon-17Cd http://flybase.org/reports/FBgn0016767 - gene - - - "C4, anon-17Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage | female , embryonic stage | early " FBgn0044115 E(rst)C14 E(rst)C14 http://flybase.org/reports/FBgn0044115 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C14, E(rst)C14" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259366 EP-634.2 - http://flybase.org/reports/FBgn0259366 gene - - - EP-634.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing margin,wing vein,chaeta" FBgn0002516 l(3)Sp10 lethal (3) Sp10 http://flybase.org/reports/FBgn0002516 - gene - - - l(3)Sp10 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259373 EP-284 - http://flybase.org/reports/FBgn0259373 gene - - - EP-284 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing" FBgn0036594 CG13047 - http://flybase.org/reports/FBgn0036594 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG13047 - CG13047 11-Aug-17 DroID_v2017_08 - - Cele\T06E4.12 - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011993 tRNA:Thr-AGT-1-5 transfer RNA:Threonine-AGT 1-5 http://flybase.org/reports/FBgn0011993 "FBgn0003833, FBgn0051589, FBgn0060045" tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "AE002708.trna49-ThrAGT, tRNA:T:AGT:AE002708-d, tRNA:thr:90Ca, CR31589, tRNA[[Thr]], chr3R.trna55-ThrAGT, tRNA-Thr-AGT-1-5, tRNA:Thr-AGT-1-5, tRNA:T:90Ca, ACU" - CR31589 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065489 l(2)SH1238 lethal (2) SH1238 http://flybase.org/reports/FBgn0065489 gene - - - "l(2)SH1238, l(2)SH2 1238" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259348 C603 - http://flybase.org/reports/FBgn0259348 gene - - - C603 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing,wing vein,chaeta" FBgn0030966 CG7280 - http://flybase.org/reports/FBgn0030966 protein_coding_gene molybdenum ion binding ; GO:0030151 | inferred from electronic annotation with InterPro:IPR005066 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 sulfite oxidase activity ; GO:0008482 | inferred from sequence or structural similarity with UniProtKB:P51687 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005066, InterPro:IPR008335 nitrate assimilation ; GO:0042128 | inferred from electronic annotation with InterPro:IPR000572 sulfur compound metabolic process ; GO:0006790 | inferred from sequence or structural similarity with UniProtKB:P51687" mitochondrial intermembrane space ; GO:0005758 | inferred from sequence or structural similarity with UniProtKB:P51687 CG7280 "IPR000572:Oxidoreductase, molybdopterin-binding domain, IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR005066:Moybdenum cofactor oxidoreductase, dimerisation, IPR008335:Eukaryotic molybdopterin oxidoreductase, IPR018506:Cytochrome b5, heme-binding site, IPR014756:Immunoglobulin E-set" CG7280 11-Aug-17 DroID_v2017_08 Drer\suox - Cele\suox-1 Xtro\suox Mmus\Suox Hsap\SUOX viable FBgn0010769 l(3)02104 lethal (3) 02104 http://flybase.org/reports/FBgn0010769 - gene - - - l(3)02104 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035639 kri krishah http://flybase.org/reports/FBgn0035639 protein_coding_gene uracil phosphoribosyltransferase activity ; GO:0004845 | inferred from direct assay uridine kinase activity ; GO:0004849 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine nucleobase metabolic process ; GO:0006206 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine nucleoside salvage ; GO:0043097 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 "anon-EST:Posey275, kri, uprt, CG5537" "IPR029057:Phosphoribosyltransferase-like, IPR000836:Phosphoribosyltransferase domain" CG5537 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-243j20.2, Drer\ctnnb2, Drer\uck2b, Drer\jupb, Drer\uckl1a, Drer\ctnnb1, Drer\jupa, Drer\uckl1b, Drer\uck1, Drer\uprt, Drer\uck2a" "Scer\URK1, Scer\FUR1" "Cele\C47B2.2, Cele\F19B6.1" "Xtro\uprt, Xtro\uck2, Xtro\ctnnb1, Xtro\uck1, Xtro\jup" "Mmus\Uckl1, Mmus\Jup, Mmus\Uck1, Mmus\Uck2, Mmus\Ctnnb1, Mmus\Uprt" "Hsap\UCK1, Hsap\UPRT, Hsap\CTNNB1, Hsap\UCK2, Hsap\JUP, Hsap\UCKL1" viable DRSC10515 I 1.571681505 -0.069839514 0.52852737 0.138679518 -0.12533288 0.765727549 FBgn0010811 l(3)03691 lethal (3) 03691 http://flybase.org/reports/FBgn0010811 - gene - - - l(3)03691 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061011 l(3)S026203b lethal (3) S026203b http://flybase.org/reports/FBgn0061011 gene - - - "0262/03, l(3)S026203b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0060373 l(3)S136708 lethal (3) S136708 http://flybase.org/reports/FBgn0060373 gene - - - "1367/08, l(3)S136708" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038789 Ir92a Ionotropic receptor 92a http://flybase.org/reports/FBgn0038789 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 extracellular ammonia-gated ion channel activity ; GO:0036081 | inferred from direct assay olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay cellular response to ammonia ; GO:1903718 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype positive regulation of calcium-mediated signaling ; GO:0050850 | inferred from direct assay cellular response to amine stimulus ; GO:0071418 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir92a, CG15685, IR92a, DmelIR92a" IPR001320:Ionotropic glutamate receptor CG15685 11-Aug-17 DroID_v2017_08 - - "Cele\glr-7, Cele\glr-3" - - Hsap\GRID2 "viable,smell perception defective" sensillum coeloconicum of antennal segment 3 FBgn0033431 CG1827 - http://flybase.org/reports/FBgn0033431 protein_coding_gene N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity ; GO:0003948 | inferred from sequence or structural similarity with UniProtKB:P20933 protein deglycosylation ; GO:0006517 | inferred from sequence or structural similarity with UniProtKB:P20933 lysosome ; GO:0005764 | inferred from sequence or structural similarity with UniProtKB:P20933 "CG1827, cg1827" "IPR000246:Peptidase T2, asparaginase 2, IPR029055:Nucleophile aminohydrolases, N-terminal" CG1827 11-Aug-17 DroID_v2017_08 "Drer\aga, Drer\zgc:153169" - Cele\R04B3.2 Xtro\aga Mmus\Aga Hsap\AGA viable FBgn0065495 l(2)SH1224 lethal (2) SH1224 http://flybase.org/reports/FBgn0065495 gene - - - "l(2)SH1224, l(2)SH2 1224" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053642 CG33642 - http://flybase.org/reports/FBgn0053642 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33642 IPR010512:Protein of unknown function DUF1091 CG33642 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003357 Jon99Ciii Jonah 99Ciii http://flybase.org/reports/FBgn0003357 "FBgn0001288, FBgn0011833, FBgn0051362" protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from sequence model proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "Ser99Db, 99Calpha, Jon99Cbeta, Jon99Calpha, Jon99Cbetaiii, Jon99Calphaii, SP143, CG15519, SER2, Ser5, Ser2, Jon99C1, Jon99C2, Jon99C, CG31362, JonC, Jon99B, Jon99Ciii" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG31362 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013341 Su(var)25F26B Su(var)25F26B http://flybase.org/reports/FBgn0013341 - gene - - - Su(var)25F26B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002200 l(3)67Ad lethal (3) 67Ad http://flybase.org/reports/FBgn0002200 - gene - - - l(3)67Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0266967 CR45418 - http://flybase.org/reports/FBgn0266967 non_protein_coding_gene - - - CR45418 - CR45418 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016821 l(1)L8 lethal (1) L8 http://flybase.org/reports/FBgn0016821 - gene - - - "l(1)L8, L8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003429 slo slowpoke http://flybase.org/reports/FBgn0003429 FBgn0046797 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Slob large conductance calcium-activated potassium channel activity ; GO:0060072 | inferred from biological aspect of ancestor with PANTHER:PTN000002875 calcium-activated potassium channel activity ; GO:0015269 | inferred from direct assay calcium-activated potassium channel activity ; GO:0015269 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P12370 voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000002873 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MR31 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 circadian rhythm ; GO:0007623 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from direct assay circadian behavior ; GO:0048512 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | non-traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement response to drug ; GO:0042493 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | non-traceable author statement membrane ; GO:0016020 | inferred from direct assay voltage-gated potassium channel complex ; GO:0008076 | inferred from biological aspect of ancestor with PANTHER:PTN000002873 neuron projection ; GO:0043005 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "dSlo, dslo, Dslo, CG10693, fSlo, BcDNA:GH10751, slo, Slo, Slo1, dSlo1" "IPR003929:Potassium channel, BK, alpha subunit, IPR005821:Ion transport domain, IPR016040:NAD(P)-binding domain, IPR024939:Calcium-activated potassium channel Slo-1, IPR028325:Voltage-gated potassium channel" CG10693 11-Aug-17 DroID_v2017_08 "Drer\kcnma1a, Drer\kcnma1b" - Cele\slo-1 Xtro\kcnma1 "Mmus\Kcnu1, Mmus\Kcnma1" "Hsap\KCNU1, Hsap\KCNMA1" adult stage adult head

"flight defective,viable,fertile,chemosensitive behavior defective,neurophysiology defective,chemical sensitive,circadian rhythm defective,recessive,behavior defective,chemical resistant,neuroanatomy defective,courtship behavior defective,male,heat sensitive,lethal" "antennal basiconic sensillum ab12,adult olfactory receptor neuron ab11a,indirect flight muscle,neuron,NMJ bouton,supernumerary,neuromuscular junction,muscle fiber,heat sensitive,neuromuscular junction | heat sensitive" FBgn0024688 aos::vn argos::vn http://flybase.org/reports/FBgn0024688 - engineered_fusion_gene - - - "gil::vn, argos::vn, aos::vn" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,eye,ommatidium,anterior crossvein,wing,ectopic,posterior" FBgn0022083 l(2)k07509 lethal (2) k07509 http://flybase.net/reports/FBgn0022083.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0037410 Osi2 Osiris 2 http://flybase.org/reports/FBgn0037410 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi2, CG1148" IPR012464:Protein of unknown function DUF1676 CG1148 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0037186 CG11241 - http://flybase.org/reports/FBgn0037186 protein_coding_gene alanine-glyoxylate transaminase activity ; GO:0008453 | inferred from biological aspect of ancestor with PANTHER:PTN000241036 identical protein binding ; GO:0042802 | inferred from biological aspect of ancestor with PANTHER:PTN000241033 pyridoxal phosphate binding ; GO:0030170 | inferred from biological aspect of ancestor with PANTHER:PTN000241033 - mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000241036 CG11241 "IPR005814:Aminotransferase class-III, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG11241 11-Aug-17 DroID_v2017_08 Drer\agxt2 Scer\ARG8 Cele\T09B4.8 Xtro\agxt2 Mmus\Agxt2 Hsap\AGXT2 FBgn0036815 HipHop HP1-HOAP-interacting protein http://flybase.org/reports/FBgn0036815 protein_coding_gene - CENP-A containing nucleosome assembly ; GO:0034080 | inferred from genetic interaction with Chrac-14 neurogenesis ; GO:0022008 | inferred from mutant phenotype protection from non-homologous end joining at telomere ; GO:0031848 | inferred from direct assay "chromosome, telomeric region ; GO:0000781 | inferred from direct assay" "CG6874, BcDNA:RE10558, hiphop, HipHop, l(3)neo26, HIPHOP, Hiphop" - CG6874 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0033280 CG12126 - http://flybase.org/reports/FBgn0033280 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT16918, CG12126" - CG12126 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027112 mei-P8 mei-P8 http://flybase.org/reports/FBgn0027112 - gene - - - mei-P8 - - 11-Aug-17 DroID_v2017_08 - - - - - - meiotic cell cycle defective FBgn0266147 CR44853 - http://flybase.org/reports/FBgn0266147 non_protein_coding_gene - - - CR44853 - CR44853 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002477 l(3)SG32 lethal (3) SG32 http://flybase.org/reports/FBgn0002477 - gene - - - "l(3)C21L, l(3)SG32" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002148 l(2)K534 lethal (2) K534 http://flybase.org/reports/FBgn0002148 - gene - - - l(2)K534 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025128 su(RpII140[Z36])S19 su(RpII140[Z36])S19 http://flybase.org/reports/FBgn0025128 - gene - - - "Z36[S19], su(RpII140[Z36])S19" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267174 CR45614 - http://flybase.org/reports/FBgn0267174 non_protein_coding_gene - - - CR45614 - CR45614 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024576 l(3)rK344 lethal (3) rK344 http://flybase.org/reports/FBgn0024576 - gene - - - l(3)rK344 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061049 l(3)S023434b lethal (3) S023434b http://flybase.org/reports/FBgn0061049 gene - - - "0234/34, l(3)S023434b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022239 l(2)k02505 lethal (2) k02505 http://flybase.org/reports/FBgn0022239 - gene - - - l(2)k02505 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035830 CG8209 - http://flybase.org/reports/FBgn0035830 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "anon-WO0172774.138, CG8209" "IPR015940:Ubiquitin-associated domain, IPR001012:UBX domain, IPR009060:UBA-like, IPR013087:Zinc finger C2H2-type, IPR029071:Ubiquitin-related domain" CG8209 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-173p19.1, Drer\ubxn1" "Scer\UBX7, Scer\UBX6" "Cele\ubxn-4, Cele\ubxn-1" "Xtro\ubxn1, Xtro\ubxn4" "Mmus\Ubxn1, Mmus\Ubxn4" "Hsap\UBXN4, Hsap\UBXN1" "viable,fertile" FBgn0062580 Mod(var)26 Mod(var)26 http://flybase.org/reports/FBgn0062580 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "26, Mod(var)26" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0051342 CG31342 - http://flybase.org/reports/FBgn0051342 protein_coding_gene - - - "CG7472, CG18551, CG31342" IPR011993:PH domain-like CG31342 11-Aug-17 DroID_v2017_08 "Drer\sdcbp, Drer\sdcbp2" - - Xtro\sdcbp "Mmus\Sdcbp2, Mmus\Sdcbp" "Hsap\SDCBP, Hsap\SDCBP2" FBgn0028185 l(3)S024020a lethal (3) S024020a http://flybase.org/reports/FBgn0028185 gene - - - "0240/20, l(3)S024020, l(3)S024020a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,recessive" FBgn0002830 ms(2)E9 male sterile (2) E9 http://flybase.org/reports/FBgn0002830 - gene - - - "ms2.9, ms(2)2.9, ms(2)E9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0060478 l(3)S111116b lethal (3) S111116b http://flybase.org/reports/FBgn0060478 gene - - - "1111/16, l(3)S111116b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0038643 CG14300 - http://flybase.org/reports/FBgn0038643 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 molecular_function ; GO:0003674 | no biological data available chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 cellular_component ; GO:0005575 | no biological data available CG14300 IPR002557:Chitin binding domain CG14300 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0036942 CG7328 - http://flybase.org/reports/FBgn0036942 protein_coding_gene fructokinase activity ; GO:0008865 | inferred from sequence or structural similarity with HGNC:6315 ketohexokinase activity ; GO:0004454 | inferred from sequence or structural similarity with HGNC:6315 fructose metabolic process ; GO:0006000 | inferred from electronic annotation with InterPro:IPR034093 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:6315 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6315 CG7328 "IPR002173:Carbohydrate/puine kinase, PfkB, conserved site, IPR011611:Carbohydrate kinase PfkB, IPR034093:Ketohexokinase, IPR029056:Ribokinase-like" CG7328 11-Aug-17 DroID_v2017_08 Drer\khk Scer\RBK1 "Cele\grl-3, Cele\grl-29, Cele\grl-31, Cele\grl-5, Cele\grl-27, Cele\grl-21, Cele\grl-28, Cele\grl-15, Cele\grl-30, Cele\R07H5.8, Cele\grl-20, Cele\grl-26, Cele\grl-18, Cele\grl-6" Xtro\khk Mmus\Khk Hsap\KHK viable DRSC10812 K 0.606226763 0.042808107 -1.140026465 0.332921219 -0.024964772 2.220670415 FBgn0015496 l(3)65ACf lethal (3) 65ACf http://flybase.org/reports/FBgn0015496 - gene - - - "VI, l(3)65ACf, l(3)k65ACf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000010 aa anarista http://flybase.org/reports/FBgn0000010 - gene - - - "al-b, aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "arista,wing" FBgn0050413 CG30413 - http://flybase.org/reports/FBgn0050413 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30413 IPR031734:Transcription activator MBF2 CG30413 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033090 CG15909 - http://flybase.org/reports/FBgn0033090 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15909 - CG15909 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016990 ms(3)1342A ms(3)1342A http://flybase.org/reports/FBgn0016990 - gene - - - ms(3)1342A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019788 l(1)15 lethal (1) 15 http://flybase.org/reports/FBgn0019788 - gene - - - l(1)15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033225 CG1550 - http://flybase.org/reports/FBgn0033225 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR013815 catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR013815 cellular protein modification process ; GO:0006464 | inferred from electronic annotation with InterPro:IPR004344 - CG1550 "IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR013815:ATP-grasp fold, subdomain 1, IPR027749:Tubulin--tyrosine ligase-like protein 12" CG1550 11-Aug-17 DroID_v2017_08 Drer\ttll12 - Cele\ttll-12 Xtro\ttll12 Mmus\Ttll12 Hsap\TTLL12 viable FBgn0004928 l(3)mbn2 lethal (3) malignant blood neoplasm 2 http://flybase.org/reports/FBgn0004928 - gene - - - "l(3)mbn-2, l(3)mbn2" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020582 anon-59Cc anon-59Cc http://flybase.org/reports/FBgn0020582 - gene - - - anon-59Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029508 Tsp42Ea Tetraspanin 42Ea http://flybase.org/reports/FBgn0029508 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG18817, Q9U3V4, CG3364, CG18742, Dm.Tsp42Ea, GH05668, BcDNA:GH05668, BcDNA:GM15292, Tsp42Ea" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG18817 11-Aug-17 DroID_v2017_08 Drer\cd63 - "Cele\tsp-1, Cele\tsp-3, Cele\tsp-7, Cele\tsp-14, Cele\tsp-2" Xtro\cd63 Mmus\Cd63 Hsap\CD63 FBgn0005037 Est-9 Esterase 9 http://flybase.org/reports/FBgn0005037 - gene - - - "EST-9, EST9, Est9, Est-9" - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0005018 dk dark on 3 http://flybase.org/reports/FBgn0005018 - gene - - - dk - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0263034 CG43329 - http://flybase.org/reports/FBgn0263034 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43329, CG12377" - CG43329 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061035 l(3)S023941a lethal (3) S023941a http://flybase.org/reports/FBgn0061035 gene - - - "0239/41, l(3)S023941a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003987 vnl venula http://flybase.org/reports/FBgn0003987 - gene - - - vnl - - 11-Aug-17 DroID_v2017_08 - - - - - - wing vein FBgn0000607 E(w[a]) Enhancer of white-apricot http://flybase.org/reports/FBgn0000607 - gene - - - E(w[a]) - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,female sterile" FBgn0000881 fs(1)M79 female sterile (1) M79 http://flybase.org/reports/FBgn0000881 - gene - - - fs(1)M79 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0032798 CG10132 - http://flybase.org/reports/FBgn0032798 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay CG10132 "IPR001680:WD40 repeat, IPR007111:NACHT nucleoside triphosphatase, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019775:WD40 repeat, conserved site" CG10132 11-Aug-17 DroID_v2017_08 - - Cele\T05C3.2 - Mmus\Ttc41 Hsap\NWD1 viable FBgn0259604 B1514 - http://flybase.org/reports/FBgn0259604 gene - - - B1514 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0067897 IM7 Immune induced molecule 7 http://flybase.org/reports/FBgn0067897 gene - defense response ; GO:0006952 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "DIM 7, IM7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265707 CR44514 - http://flybase.org/reports/FBgn0265707 non_protein_coding_gene - - - "incRNA.404, CR44514, lincRNA.404" - CR44514 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015492 l(3)65ACb lethal (3) 65ACb http://flybase.org/reports/FBgn0015492 - gene - - - "II, l(3)65ACb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032414 CG17211 - http://flybase.org/reports/FBgn0032414 protein_coding_gene integrin binding ; GO:0005178 | inferred from sequence or structural similarity with tnc epithelial tube morphogenesis ; GO:0060562 | inferred from sequence or structural similarity with tnc extracellular matrix ; GO:0031012 | inferred from sequence or structural similarity with tnc CG17211 IPR001007:VWFC domain CG17211 11-Aug-17 DroID_v2017_08 "Drer\scaf11, Drer\scaf1, Drer\phrf1" Scer\BMT6 - - "Mmus\Scaf11, Mmus\Scaf1, Mmus\Phrf1" "Hsap\SCAF1, Hsap\PHRF1, Hsap\SCAF11" FBgn0002682 mat(2)twg maternal effect twisted gastrulation http://flybase.org/reports/FBgn0002682 - gene - - - mat(2)twg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002295 l(3)80Ff lethal (3) 80Ff http://flybase.org/reports/FBgn0002295 - gene - - - "l4B, l(3)Lh4B, l(3)80Ff, 80Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001500 l(1)10Cc lethal (1) 10Cc http://flybase.org/reports/FBgn0001500 - gene - - - "L20, HA10, HA-10, l(1)L20, l(1)10Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" FBgn0004744 l(3)85Fa lethal (3) 85Fa http://flybase.org/reports/FBgn0004744 - gene - - - l(3)85Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053255 CR33255 - http://flybase.org/reports/FBgn0053255 pseudogene_attribute - - - "CG33255, CR33255" - CR33255 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265370 CR44311 - http://flybase.org/reports/FBgn0265370 non_protein_coding_gene - - - "CR44311, lincRNA.26" - CR44311 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065636 l(2)SH0769 lethal (2) SH0769 http://flybase.org/reports/FBgn0065636 gene - - - "l(2)SH0769, l(2)SH2 0769" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001937 l(2)25Fc lethal (2) 25Fc http://flybase.org/reports/FBgn0001937 - gene - - - "l(2)gdh-15, l(2)25Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263469 snoRNA:SC35-b - http://flybase.org/reports/FBgn0263469 snoRNA_gene - - - snoRNA:SC35-b - CR43584 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002273 l(3)70Aa lethal (3) 70Aa http://flybase.org/reports/FBgn0002273 - gene - - - "l(3)ZF1, l(3)70Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038796 eIF3g2 eukaryotic translation initiation factor 3 subunit g2 http://flybase.org/reports/FBgn0038796 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000039396 translational initiation ; GO:0006413 | inferred from sequence or structural similarity regulation of cell cycle ; GO:0051726 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000039396 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity "eIF3-S4, cg10881, CG10881, eIF3g2, eIF3gb" "IPR000504:RNA recognition motif domain, IPR017334:Eukaryotic translation initiation factor 3 subunit G, IPR024675:Eukaryotic translation initiation factor 3 subunit G, N-terminal, IPR034240:eIF3G, RNA recognition motif" CG10881 11-Aug-17 DroID_v2017_08 Drer\eif3g Scer\TIF35 Cele\eif-3.G Xtro\eif3g Mmus\Eif3g Hsap\EIF3G lethal DRSC28960 K -0.231662238 -0.036076986 0.322971999 0.975098108 1.819966063 0.16050251 FBgn0011221 goul goulash http://flybase.org/reports/FBgn0011221 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - goul - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0019821 eZ6 eZ6 http://flybase.org/reports/FBgn0019821 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available eZ6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025382 Rab27 Rab27 http://flybase.org/reports/FBgn0025382 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with Rph GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" melanosome transport ; GO:0032402 | inferred from biological aspect of ancestor with PANTHER:PTN001178482 sleep ; GO:0030431 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 positive regulation of exocytosis ; GO:0045921 | inferred from biological aspect of ancestor with PANTHER:PTN001178482 exosomal secretion ; GO:1990182 | inferred from mutant phenotype Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 synaptic vesicle ; GO:0008021 | inferred from direct assay melanosome ; GO:0042470 | inferred from biological aspect of ancestor with PANTHER:PTN001178482 synapse ; GO:0045202 | inferred from direct assay secretory granule ; GO:0030141 | inferred from biological aspect of ancestor with PANTHER:PTN001178482 "dm-Rab27, AAF45635, AAF45634, EG:80H7.4, DmRab27, CG14791, Rab27, rab27, 18543235, O76901" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG14791 11-Aug-17 DroID_v2017_08 "Drer\rab27b, Drer\rab27a" "Scer\YPT1, Scer\SEC4" Cele\aex-6 "Xtro\rab27a, Xtro\rab27b" "Mmus\Rab27a, Mmus\Rab27b" "Hsap\RAB27B, Hsap\RAB27A" "viable,fertile,sleep defective" FBgn0038039 CG5196 - http://flybase.org/reports/FBgn0038039 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay CG5196 "IPR001594:Palmitoyltransferase, DHHC domain" CG5196 11-Aug-17 DroID_v2017_08 Drer\zdhhc6 "Scer\PFA3, Scer\SWF1, Scer\ERF2, Scer\PFA4" "Cele\dhhc-6, Cele\dhhc-5" Xtro\zdhhc6 Mmus\Zdhhc6 Hsap\ZDHHC6 viable FBgn0004936 ABO-2R Abnormal Oocyte on 2R http://flybase.org/reports/FBgn0004936 - region - - - "ABO, ABO-2R" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259963 Sfp33A2 Seminal fluid protein 33A2 http://flybase.org/reports/FBgn0259963 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp33A2, CG42473" - CG42473 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002665 mat(2)ea-B maternal effect early arrest B http://flybase.org/reports/FBgn0002665 - gene - - - "mat(2)earlyPG44, mat(2)ea-B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0029001 ms(3)08724 ms(3)08724 http://flybase.org/reports/FBgn0029001 gene - - - "P1732, ms(3)08724" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262533 CR43087 - http://flybase.org/reports/FBgn0262533 pseudogene_attribute - - - CR43087 - CR43087 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267825 L Lobe http://flybase.org/reports/FBgn0267825 protein_coding_gene - negative regulation of programmed cell death ; GO:0043069 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype cytoplasm ; GO:0005737 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay "L, fee" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000269 ccb central complex broad http://flybase.org/reports/FBgn0000269 - gene - central complex development ; GO:0048036 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype - ccb - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,recessive,behavior defective,memory defective" "ellipsoid body,supernumerary,adult central complex,fan-shaped body,protocerebral bridge" FBgn0265472 Apc::Apc2 - http://flybase.org/reports/FBgn0265472 engineered_fusion_gene - - - Apc::Apc2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065428 l(2)SH1504 lethal (2) SH1504 http://flybase.org/reports/FBgn0065428 gene - - - "l(2)SH1504, l(2)SH2 1504" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001743 l(1)HM13 lethal (1) HM13 http://flybase.org/reports/FBgn0001743 - gene - - - l(1)HM13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female sterile" FBgn0005084 fs(2)OW808 female sterile (2) OW808 http://flybase.org/reports/FBgn0005084 - gene - - - fs(2)OW808 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050071 CG30071 - http://flybase.org/reports/FBgn0050071 protein_coding_gene - - - CG30071 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC22029 E 0.68798794 0.156759211 1.402462133 1.586225263 0.353631181 0.660610817 FBgn0011169 l(1)291-3 lethal (1) 291-3 http://flybase.org/reports/FBgn0011169 FBgn0010199 gene - - - "291-3, l(1)291-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051546 CG31546 - http://flybase.org/reports/FBgn0051546 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "CG2907, anon-WO0140519.189, CG31546" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG31546 11-Aug-17 DroID_v2017_08 "Drer\dhrs1, Drer\zgc:113054, Drer\elovl8b, Drer\pecr, Drer\zgc:101858, Drer\elovl7a, Drer\hsd17b14, Drer\elovl2, Drer\decr1, Drer\elovl1b, Drer\hsdl2, Drer\hsd17b8, Drer\elovl5, Drer\decr2, Drer\cbr4, Drer\dhrs7, Drer\elovl1a, Drer\elovl7b, Drer\elovl8a, Drer\elovl4a, Drer\bdh2, Drer\elovl4b" "Scer\SPS19, Scer\IRC24, Scer\OAR1, Scer\YIR035C" "Cele\F26D2.15, Cele\F28H7.2, Cele\C06E4.3, Cele\Y47G6A.21, Cele\C33E10.10, Cele\ZK829.1, Cele\dhs-23, Cele\Y47G6A.22, Cele\F25D1.5, Cele\dhs-11, Cele\dhs-25, Cele\dhs-14" "Xtro\pecr, Xtro\decr1, Xtro\hsdl2, Xtro\elovl7, Xtro\cbr4, Xtro\MGC79752, Xtro\hsd17b14, Xtro\elovl5, Xtro\decr2, Xtro\dhrs7, Xtro\hsd17b8, Xtro\elovl1, Xtro\MGC147226, Xtro\elovl2, Xtro\dhrs4" "Mmus\Hsd17b14, Mmus\Elovl4, Mmus\Elovl7, Mmus\Hsdl2, Mmus\Dhrs2, Mmus\Decr2, Mmus\Cbr4, Mmus\Dhrs7, Mmus\Bdh2, Mmus\Elovl2, Mmus\Dhrs1, Mmus\Decr1, Mmus\Pecr, Mmus\Elovl5, Mmus\H2-Ke6, Mmus\Dhrs4" "Hsap\ELOVL7, Hsap\DHRS4, Hsap\HSDL2, Hsap\DHRS7, Hsap\DHRS4L2, Hsap\CBR4, Hsap\DHRS2, Hsap\ELOVL4, Hsap\ELOVL2, Hsap\HSD17B8, Hsap\DECR2, Hsap\BDH2, Hsap\HSD17B14, Hsap\DHRS1, Hsap\ELOVL5, Hsap\ELOVL1, Hsap\DECR1, Hsap\PECR" viable FBgn0001639 l(1)dn19 lethal (1) discs normal 19 http://flybase.org/reports/FBgn0001639 - gene - - - "l(1)d.norm.-19, l(1)dn19" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263880 l(3)A38 - http://flybase.org/reports/FBgn0263880 gene - - - l(3)A38 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0036191 Sugb Sugar baby http://flybase.org/reports/FBgn0036191 protein_coding_gene - determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype - "CG7334, Sugb, Sug, sug" "IPR024989:Major facilitator superfamily associated domain, IPR020846:Major facilitator superfamily domain" CG7334 11-Aug-17 DroID_v2017_08 "Drer\mfsd6a, Drer\mfsd6b, Drer\mfsd6l" "Scer\TCM62, Scer\SLA1, Scer\GDS1, Scer\SEC72, Scer\GDH2, Scer\GCR2, Scer\YHR140W" "Cele\F09F3.5, Cele\R13A5.9, Cele\skpo-1" "Xtro\mfsd6l, Xtro\mfsd6" "Mmus\Ptgs2, Mmus\Mfsd6l, Mmus\Mfsd6" "Hsap\SCN10A, Hsap\MFSD6, Hsap\PTGS2, Hsap\MFSD6L" "viable,fertile,long lived" FBgn0052199 CG32199 - http://flybase.org/reports/FBgn0052199 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG13382, CG32199" "IPR011990:Tetratricopeptide-like helical domain, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG32199 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\p4ha1a, Drer\p4htm, Drer\p4ha3, Drer\zgc:152670, Drer\zgc:158254, Drer\p4ha2" - "Cele\C14E2.4, Cele\phy-3, Cele\phy-4, Cele\phy-2, Cele\Y43F8B.19" "Xtro\p4ha2, Xtro\p4ha1, Xtro\p4ha3" "Mmus\P4ha2, Mmus\P4htm, Mmus\P4ha3, Mmus\P4ha1" "Hsap\P4HA1, Hsap\P4HA2, Hsap\P4HA3, Hsap\P4HTM" viable FBgn0265850 CR44639 - http://flybase.org/reports/FBgn0265850 non_protein_coding_gene - - - CR44639 - CR44639 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036665 CG13024 - http://flybase.org/reports/FBgn0036665 protein_coding_gene - - - "BcDNA:RH61817, CG13024" - CG13024 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032437 CR17024 - http://flybase.org/reports/FBgn0032437 pseudogene_attribute - - - "CG17024, CR17024" - CR17024 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032377 CG14937 - http://flybase.org/reports/FBgn0032377 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG14937, FBXO17" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG14937 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015767 Mst302 Male-specific transcript 302 http://flybase.org/reports/FBgn0015767 - gene - - - Mst302 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036552 CG17028 - http://flybase.org/reports/FBgn0036552 protein_coding_gene inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol monophosphate 1-phosphatase activity ; GO:0008934 | non-traceable author statement inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from sequence or structural similarity with HGNC:6050 "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550, InterPro:IPR020552 inositol phosphate dephosphorylation ; GO:0046855 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol metabolic process ; GO:0006020 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 dephosphorylation ; GO:0016311 | non-traceable author statement inositol phosphate dephosphorylation ; GO:0046855 | inferred from sequence or structural similarity with HGNC:6050" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6050 "IMP, CG17028" "IPR000760:Inositol monophosphatase-like, IPR033942:Inositol monophosphatase, IPR020550:Inositol monophosphatase, conserved site, IPR020552:Inositol monophosphatase, Lithium-sensitive, IPR020583:Inositol monophosphatase, metal-binding site" CG17028 11-Aug-17 DroID_v2017_08 "Drer\impa1, Drer\impa2" "Scer\INM1, Scer\INM2" Cele\ttx-7 "Xtro\impa1, Xtro\impa2" "Mmus\Impad1, Mmus\Impa1, Mmus\Impa2" "Hsap\IMPA2, Hsap\IMPAD1, Hsap\IMPA1" viable DRSC29850 K 0.345656475 0.83111402 0.29969736 -0.129991268 1.610369987 -0.166102827 FBgn0036224 Rpt4R Regulatory particle triple-A ATPase 4-related http://flybase.org/reports/FBgn0036224 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ATPase activity ; GO:0016887 | inferred from sequence model proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with Rpt4 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000005785 nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" "Dm_Rpt4c, DmCG7257, Rpt4R, 7257, CG7257" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7257 11-Aug-17 DroID_v2017_08 "Drer\psmc5, Drer\wdr12, Drer\psmc2, Drer\psmc6" Scer\RPT4 "Cele\rpt-4, Cele\F56F11.4, Cele\rpt-6" "Xtro\wdr12, Xtro\psmc2, Xtro\psmc5, Xtro\psmc6" "Mmus\Psmc5, Mmus\Psmc6, Mmus\Psmc2, Mmus\Wdr12" "Hsap\PSMC6, Hsap\PSMC2, Hsap\WDR12, Hsap\PSMC5" "partially lethal - majority die,some die during pupal stage" FBgn0263408 CR43454 - http://flybase.org/reports/FBgn0263408 non_protein_coding_gene - - - CR43454 - CR43454 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020293 l(1)EH275a lethal (1) EH275a http://flybase.org/reports/FBgn0020293 - gene - - - l(1)EH275a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0038974 CG5377 - http://flybase.org/reports/FBgn0038974 protein_coding_gene - - - CG5377 "IPR029058:Alpha/Beta hydrolase fold, IPR000073:Alpha/beta hydrolase fold-1" CG5377 11-Aug-17 DroID_v2017_08 Drer\bphl "Scer\IMO32, Scer\LPX1" Cele\K01A2.5 Xtro\bphl Mmus\Bphl Hsap\BPHL viable FBgn0053516 dpr3 defective proboscis extension response 3 http://flybase.org/reports/FBgn0053516 protein_coding_gene molecular_function ; GO:0003674 | no biological data available store-operated calcium entry ; GO:0002115 | inferred from mutant phenotype sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG15381, CG15380, CG15379, Dpr-3, CT35425, CG33516, dpr3, CRACM2, Dpr3" "IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype, IPR003598:Immunoglobulin subtype 2" CG33516 11-Aug-17 DroID_v2017_08 "Drer\itgb4, Drer\lrit3b, Drer\lrit3a, Drer\kirrelb, Drer\ncam1b, Drer\LOC101885444, Drer\si:ch1073-459j12.1, Drer\kirrel3a, Drer\LOC101885725, Drer\lrit1a, Drer\kirrel3l, Drer\kirrel3b, Drer\ush2a, Drer\si:ch211-163c2.2, Drer\sdk1a, Drer\sdk1b, Drer\kirrela, Drer\dscama, Drer\LOC100333196, Drer\paplna, Drer\igsf9a, Drer\igsf9bb, Drer\lrit1b, Drer\si:ch211-264f5.6, Drer\si:dkey-65b12.12" - Cele\zig-8 "Xtro\kirrel2, Xtro\nfasc, Xtro\papln, Xtro\obsl1, Xtro\lrit3, Xtro\igsf9b" "Mmus\Sdk1, Mmus\Kirrel3, Mmus\Lrit1, Mmus\Lrit3, Mmus\Ptprq, Mmus\Igsf9b, Mmus\Kirrel, Mmus\Kirrel2, Mmus\Papln" "Hsap\KIRREL2, Hsap\IGSF9B, Hsap\KIRREL3, Hsap\LRIT3, Hsap\USH2A, Hsap\LRIT1, Hsap\PAPLN, Hsap\SDK1, Hsap\KIRREL" viable FBgn0032585 CG4580 - http://flybase.org/reports/FBgn0032585 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG4580 "IPR000718:Peptidase M13, IPR018497:Peptidase M13, C-terminal domain, IPR008753:Peptidase M13, N-terminal domain" CG4580 11-Aug-17 DroID_v2017_08 "Drer\ece2b, Drer\phex, Drer\mmel1, Drer\ece1" - "Cele\nep-13, Cele\nep-3, Cele\nep-8, Cele\nep-23, Cele\nep-9, Cele\nep-19, Cele\nep-24, Cele\nep-21, Cele\nep-26, Cele\nep-5, Cele\nep-20, Cele\nep-10, Cele\nep-7, Cele\nep-6, Cele\nep-18, Cele\nep-12" "Xtro\ecel1, Xtro\ece1, Xtro\ece2, Xtro\mmel1" "Mmus\Ecel1, Mmus\Ece2, Mmus\Ece1, Mmus\Mme, Mmus\Phex, Mmus\Kel, Mmus\Mmel1" "Hsap\KEL, Hsap\ECE1, Hsap\MME, Hsap\ECE2, Hsap\PHEX, Hsap\ECEL1, Hsap\MMEL1" viable FBgn0029649 CG4116 - http://flybase.org/reports/FBgn0029649 protein_coding_gene - - - CG4116 - CG4116 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0025483 l(3)Ax27 lethal (3) Ax27 http://flybase.org/reports/FBgn0025483 - gene - - - "Ax27, l(3)Ax27" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030684 CG8260 - http://flybase.org/reports/FBgn0030684 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8260 "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR011705:BTB/Kelch-associated, IPR031750:Domain of unknown function DUF4734" CG8260 11-Aug-17 DroID_v2017_08 Drer\klhl41a - Cele\kel-3 - - - "viable,visible" trichogen cell FBgn0000820 fs(1)K1193 female sterile (1) K1193 http://flybase.org/reports/FBgn0000820 - gene - - - fs(1)K1193 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0023177 Pp4-19C Protein phosphatase 19C http://flybase.org/reports/FBgn0023177 "FBgn0005784, FBgn0031112, FBgn0031113, FBgn0042229, FBgn0052505" protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006186 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement" microtubule-based process ; GO:0007017 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement "centrosome ; GO:0005813 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from physical interaction with Cenp-C protein phosphatase 4 complex ; GO:0030289 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay" "PPP4c, DmPpp4-19C, PP4, CG1459, pp4, PP4 19C, PPX, PpX, CG18339, CG1596, CG32505, Pp4-19C, PP1, PP4C, dPP4, PP4-19C, Ppp4c, PP4c, PP4-19c" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG32505 11-Aug-17 DroID_v2017_08 "Drer\ppp2ca, Drer\ppp4ca, Drer\zgc:56064, Drer\ppp6c, Drer\ppp2cb, Drer\ppp4cb" "Scer\PPH3, Scer\PPH22, Scer\SIT4, Scer\PPG1, Scer\YNL217W, Scer\PPH21" "Cele\pph-4.2, Cele\pph-4.1, Cele\pph-6" "Xtro\ppp6c, Xtro\ppp2cb, Xtro\ppp4c, Xtro\ppp2ca" "Mmus\Ppp2cb, Mmus\Ppp2ca, Mmus\Ppp4c, Mmus\Ppp6c" "Hsap\PPP6C, Hsap\PPP2CB, Hsap\PPP2CA, Hsap\PPP4C" "partially lethal - majority die,maternal effect,recessive,some die during embryonic stage,lethal,neuroanatomy defective,visible,some die during pupal stage,female semi-sterile,female fertile" "centrosome | embryonic stage | maternal effect,microtubule | embryonic stage | maternal effect,mitotic domain,maternal effect,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,synapse,neuromuscular junction" DRSC21251 I -1.040187241 -3.547631511 -1.103693159 -1.353044199 0.049852253 -0.769667735 FBgn0033128 Tsp42Eg Tetraspanin 42Eg http://flybase.org/reports/FBgn0033128 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG12142, Dm.Tsp42Eg, BcDNA:GM06962, Tsp42Eg" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12142 11-Aug-17 DroID_v2017_08 "Drer\tspan9b, Drer\tspan9a, Drer\tspan35, Drer\tspan34, Drer\cd63, Drer\tspan4a, Drer\zgc:64051, Drer\tspan4b, Drer\upk1a, Drer\tspan18b, Drer\tspan37, Drer\tspan18a" - "Cele\tsp-6, Cele\tsp-19, Cele\tsp-7, Cele\tsp-5, Cele\tsp-11, Cele\tsp-4, Cele\tsp-8, Cele\tsp-13, Cele\tsp-10" - "Mmus\Upk1a, Mmus\Upk1b, Mmus\Tspan18, Mmus\Tspan1, Mmus\Tspan8, Mmus\Cd63, Mmus\Tspan9, Mmus\Tspan4, Mmus\Cd53" "Hsap\TSPAN16, Hsap\TSPAN9, Hsap\CD53, Hsap\UPK1A, Hsap\TSPAN18, Hsap\TSPAN8, Hsap\TSPAN1, Hsap\TSPAN4, Hsap\UPK1B" "partially lethal - majority die,some die during pupal stage" FBgn0037368 CG1239 - http://flybase.org/reports/FBgn0037368 protein_coding_gene "methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR010675, InterPro:IPR024160" neurogenesis ; GO:0022008 | inferred from mutant phenotype - "cg1239, CG1239" "IPR010675:RNA methyltransferase bin3, C-terminal, IPR024160:Bin3-type S-adenosyl-L-methionine binding domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG1239 11-Aug-17 DroID_v2017_08 "Drer\si, Drer\mepce, Drer\si:ch1073-157b13.1" - Cele\Y17G7B.18 - "Mmus\Bcdin3d, Mmus\Mepce" "Hsap\BCDIN3D, Hsap\MEPCE" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0065368 l(2)SH1709 lethal (2) SH1709 http://flybase.org/reports/FBgn0065368 gene - - - "l(2)SH1709, l(2)SH2 1709" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265315 CR44288 - http://flybase.org/reports/FBgn0265315 non_protein_coding_gene - - - CR44288 - CR44288 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050390 Sgf29 SAGA-associated factor 29kDa http://flybase.org/reports/FBgn0050390 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay methylated histone binding ; GO:0035064 | inferred from sequence or structural similarity with HGNC:25156 histone acetylation ; GO:0016573 | inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from physical interaction with Ada2a nucleus ; GO:0005634 | inferred from direct assay "CG10509, CG30390, dSgf29, Sgf29" IPR010750:SGF29 tudor-like domain CG30390 11-Aug-17 DroID_v2017_08 Drer\sgf29 Scer\SGF29 "Cele\T22B7.4, Cele\Y17G9B.8" Xtro\sgf29 Mmus\Sgf29 Hsap\SGF29 viable FBgn0004054 zen2 zerknullt-related http://flybase.org/reports/FBgn0004054 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "z2, zpr, CG1048, BG:DS00276.10, zen2" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG1048 11-Aug-17 DroID_v2017_08 "Drer\hoxc3a, Drer\hoxa3a, Drer\mnx1, Drer\gsx1, Drer\hoxb3a, Drer\hoxb6a, Drer\hoxb8b, Drer\hoxb1b, Drer\gsx2, Drer\hoxd4a, Drer\hoxa5a, Drer\hoxc1a, Drer\mnx2a, Drer\hoxa9b, Drer\hoxb2a, Drer\hoxc4a, Drer\hoxc6b, Drer\hoxc6a, Drer\meox2a, Drer\hoxb1a, Drer\gbx2, Drer\hoxb6b, Drer\hoxd3a, Drer\hoxb4a, Drer\hoxc8a, Drer\hoxa4a, Drer\meox2b, Drer\hoxc5a, Drer\hoxa1a, Drer\hoxb7a, Drer\hoxa2b, Drer\pdx1, Drer\hoxb5b, Drer\gbx1, Drer\meox1, Drer\hoxb5a" "Scer\YOX1, Scer\YHP1, Scer\PHO2" "Cele\ceh-12, Cele\ceh-10" "Xtro\hoxc8, Xtro\hoxc3, Xtro\hoxb3, Xtro\hoxd8, Xtro\hoxd3, Xtro\hoxa2, Xtro\mnx1, Xtro\pdx1, Xtro\hoxb8, Xtro\hoxb5, Xtro\hoxc5, Xtro\hoxb2, Xtro\meox2, Xtro\hoxa1, Xtro\gbx2.1, Xtro\hoxb7, Xtro\gsx2, Xtro\hoxb4, Xtro\gsx1, Xtro\hoxd1, Xtro\hoxa5, Xtro\hoxb6, Xtro\hoxc4, Xtro\hoxb1, Xtro\hoxa3, Xtro\gbx2.2" "Mmus\Hoxc6, Mmus\Hoxb2, Mmus\Hoxa3, Mmus\Hoxd1, Mmus\Hoxb6, Mmus\Hoxc8, Mmus\Hoxd4, Mmus\Hoxb7, Mmus\Hoxa4, Mmus\Hoxa6, Mmus\Hoxb4, Mmus\Barx2, Mmus\Meox1, Mmus\Hoxb8, Mmus\Meox2, Mmus\Hoxb3, Mmus\Hoxb5, Mmus\Hoxc4, Mmus\Pdx1, Mmus\Hoxd3, Mmus\Gbx1, Mmus\Hoxb1, Mmus\Hoxa7, Mmus\Hoxc5, Mmus\Gsx1, Mmus\Mnx1, Mmus\Hoxa5, Mmus\Hoxa2, Mmus\Hoxa1, Mmus\Hoxd8, Mmus\Gbx2, Mmus\Gsx2" "Hsap\HOXA4, Hsap\HOXA3, Hsap\HOXD1, Hsap\HOXB4, Hsap\MEOX2, Hsap\HOXB6, Hsap\PDX1, Hsap\HOXD3, Hsap\HOXC4, Hsap\HOXC8, Hsap\HOXA1, Hsap\GBX1, Hsap\HOXC6, Hsap\HOXB5, Hsap\GSX2, Hsap\MNX1, Hsap\HOXA2, Hsap\HOXB3, Hsap\HOXB7, Hsap\HOXC5, Hsap\HOXB1, Hsap\HOXB2, Hsap\HOXB8, Hsap\HOXA7, Hsap\GBX2, Hsap\HOXA5, Hsap\HOXA6, Hsap\HOXD8, Hsap\GSX1, Hsap\HOXD4, Hsap\MEOX1" " embryonic stage | 3.5 hr , embryonic stage | embryonic cycle 14 , embryonic stage | extended germ band , embryonic stage | gastrula , embryonic stage | early , embryonic stage " " dorsal fold

, organism | dorsal & anterior

, amnioserosa

, organism | dorsal

, dorsal ectoderm | restricted

, embryo | dorsal

" lethal FBgn0265643 CR44450 - http://flybase.org/reports/FBgn0265643 non_protein_coding_gene - - - "CR44450, lincRNA.268" - CR44450 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026368 Sbp6 Su(H)-binding protein 6 http://flybase.org/reports/FBgn0026368 - gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "sbp6, Sbp6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019804 ksr::tor ksr::tor http://flybase.org/reports/FBgn0019804 - engineered_fusion_gene - - - ksr::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,visible,dominant" "eye,eye photoreceptor cell,ommatidium,photoreceptor cell R7" FBgn0262472 EP330 - http://flybase.org/reports/FBgn0262472 gene - - - EP330 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001346 l(1)1Ea lethal (1) 1Ea http://flybase.org/reports/FBgn0001346 - gene - - - l(1)1Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,cell lethal,germline clone" FBgn0266862 CR45323 - http://flybase.org/reports/FBgn0266862 non_protein_coding_gene - - - CR45323 - CR45323 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011204 cue cueball http://flybase.org/reports/FBgn0011204 FBgn0035225 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881 triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype primary spermatocyte growth ; GO:0007285 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern inferred from mutant phenotype - "CT5570, CG12086, ms(3)02509, cue" "IPR000033:LDLR class B repeat, IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR001881:EGF-like calcium-binding domain" CG12086 11-Aug-17 DroID_v2017_08 "Drer\lrp2a, Drer\lrp1ba, Drer\ldlrad3, Drer\lrp13, Drer\nid2b, Drer\lrp1bb, Drer\lrp1ab" "Scer\APM3, Scer\APM2, Scer\APM1" "Cele\rme-2, Cele\F14B4.1, Cele\lrp-1" - "Mmus\Lrp1b, Mmus\Egf, Mmus\Lrp1, Mmus\Lrp2, Mmus\Ldlrad3" "Hsap\LRP1, Hsap\LDLRAD3, Hsap\EGF, Hsap\LRP1B, Hsap\LRP2, Hsap\LRP5L" "male sterile,recessive,female semi-sterile,viable" "spermatocyte,primary spermatocyte cyst,testis,ovary" FBgn0030577 CG5334 - http://flybase.org/reports/FBgn0030577 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:7112 zinc ion binding ; GO:0008270 | inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:7112 cellular_component ; GO:0005575 | no biological data available CG5334 "IPR000571:Zinc finger, CCCH-type, IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR018957:Zinc finger, C3HC4 RING-type" CG5334 11-Aug-17 DroID_v2017_08 "Drer\mkrn4, Drer\rnf141, Drer\mkrn2, Drer\mkrn1" Scer\LEE1 "Cele\Y55F3AM.6, Cele\ccch-1" "Xtro\mkrn1, Xtro\mkrn2, Xtro\rnf141, Xtro\mkrn3" "Mmus\Mkrn3, Mmus\Mkrn1, Mmus\Mkrn2, Mmus\Rnf141" "Hsap\MKRN1, Hsap\MKRN2, Hsap\RNF141, Hsap\MKRN3" FBgn0046793 CG32236 - http://flybase.org/reports/FBgn0046793 protein_coding_gene - - - "NEST:bs27g09, BcDNA:GH16763, CG32236" "IPR029000:Cyclophilin-like domain, IPR029488:Hemingway/KIAA1430" CG32236 11-Aug-17 DroID_v2017_08 "Drer\ppifb, Drer\ppiaa, Drer\ppiab, Drer\ppifa" "Scer\CPR3, Scer\CPR1" - "Xtro\ppia, Xtro\ppif" "Mmus\Ranbp2, Mmus\Ppif, Mmus\Ppia" "Hsap\PPIAL4A, Hsap\LOC105371242, Hsap\PPIAL4D, Hsap\PPIAL4E, Hsap\PPIAL4C, Hsap\PPIF, Hsap\RANBP2, Hsap\PPIA, Hsap\PPIAL4G" viable DRSC08117 I 1.54780742 0.302279955 0.014388703 0.000905362 0.9071219 -0.000221745 FBgn0267510 2SrRNA-Psi:CR45850 2S ribosomal RNA pseudogene:CR45850 http://flybase.org/reports/FBgn0267510 pseudogene_attribute - - - "2SrRNA-Psi:CR45850, CR45850" - CR45850 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027214 l(1)G0332 lethal (1) G0332 http://flybase.org/reports/FBgn0027214 - gene - - - l(1)G0332 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265677 CR44484 - http://flybase.org/reports/FBgn0265677 non_protein_coding_gene - - - "lincRNA.20, CR44484" - CR44484 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037024 tzn tenzing norgay http://flybase.org/reports/FBgn0037024 protein_coding_gene hydroxyacylglutathione hydrolase activity ; GO:0004416 | inferred from electronic annotation with InterPro:IPR017782 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione ; GO:0019243 | inferred from electronic annotation with InterPro:IPR017782 response to hypoxia ; GO:0001666 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "CG4365, tzn" "IPR001279:Metallo-beta-lactamase, IPR017782:Hydroxyacylglutathione hydrolase, IPR032282:Hydroxyacylglutathione hydrolase, C-terminal domain" CG4365 11-Aug-17 DroID_v2017_08 "Drer\tmem104, Drer\hagh, Drer\mblac2, Drer\pnkd" "Scer\GLO2, Scer\GLO4" "Cele\Y17G7B.3, Cele\C03A3.2" "Xtro\haghl, Xtro\lactb2, Xtro\mblac2, Xtro\pnkd, Xtro\hagh, Xtro\tmem104" "Mmus\Pnkd, Mmus\Mblac2, Mmus\Tmem104, Mmus\Lactb2, Mmus\Haghl, Mmus\Hagh" "Hsap\HAGHL, Hsap\MBLAC2, Hsap\PNKD, Hsap\HAGH, Hsap\LACTB2, Hsap\TMEM104" viable DRSC11755 I 2.252649256 0.202467921 0.21434577 -0.178385661 0.23953024 -0.245308299 FBgn0002252 l(3)68Ed lethal (3) 68Ed http://flybase.org/reports/FBgn0002252 - gene - - - "rsg14, l(3)rsg14, l(3)68Ed" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065693 l(2)SH0641 lethal (2) SH0641 http://flybase.net/reports/FBgn0065693.html gene l(2)SH2 0641 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0019624 COX5A Cytochrome c oxidase subunit 5A http://flybase.org/reports/FBgn0019624 FBgn0023019 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P20674 cytochrome-c oxidase activity ; GO:0004129 | inferred from biological aspect of ancestor with PANTHER:PTN000367750 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProtKB:P20674 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype positive regulation of cell cycle ; GO:0045787 | inferred from mutant phenotype mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000367750" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P20674 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000367750 "COX, Va, CoVa, tend, CG14724, COXA_DROME, cova, COXA, COX5A, Cox5a" "IPR003204:Cytochrome c oxidase, subunit Va/VI" CG14724 11-Aug-17 DroID_v2017_08 "Drer\cox5aa, Drer\cox5ab" Scer\COX6 Cele\cco-2 Xtro\cox5a Mmus\Cox5a Hsap\COX5A "lethal,recessive,mitotic cell cycle defective,somatic clone,increased cell number,visible,body color defective,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,lens,eye disc posterior to the morphogenetic furrow,cone cell,ommatidial precursor cluster,lamellocyte | third instar larval stage,eye disc,trichogen cell,mesothoracic tergum" DRSC16611 IK -1.158527569 -1.69573182 -1.018231422 -0.830830332 1.678435299 0.731583849 FBgn0019668 mwr more wright http://flybase.org/reports/FBgn0019668 - gene molecular_function ; GO:0003674 | no biological data available female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mwr - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive,lethal,maternal effect,partially" FBgn0041741 l(2)44Fr lethal (2) 44Fr http://flybase.org/reports/FBgn0041741 gene - - - l(2)44Fr - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032888 CheB38c Chemosensory protein B 38c http://flybase.org/reports/FBgn0032888 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model "CG14405, CheB38c" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster, IPR010512:Protein of unknown function DUF1091" CG14405 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030812 wcy wacky http://flybase.org/reports/FBgn0030812 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype positive regulation of TORC1 signaling ; GO:1904263 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype lysosome ; GO:0005764 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "BP1032, CG34014, CG8949, wcy, XE14" IPR001202:WW domain CG8949 11-Aug-17 DroID_v2017_08 "Drer\wacb, Drer\waca" - "Cele\Y40B1A.1, Cele\Y40B1A.2" Xtro\wac Mmus\Wac Hsap\WAC FBgn0028134 l(3)S050407b lethal (3) S050407b http://flybase.org/reports/FBgn0028134 gene - - - "0504/07, l(3)S050407b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262004 CG42822 - http://flybase.org/reports/FBgn0262004 protein_coding_gene - - - "CG42822, CG34035, BP1011" - CG42822 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083951 CG34115 - http://flybase.org/reports/FBgn0083951 protein_coding_gene - - - CG34115 - CG34115 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263516 mir-4958 mir-4958 stem loop http://flybase.org/reports/FBgn0263516 miRNA_gene - - - "mir-4958, CR43501, dme-mir-4958" - CR43501 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082914 wst wasted http://flybase.org/reports/FBgn0082914 gene - sperm storage ; GO:0046693 | inferred from mutant phenotype sperm entry ; GO:0035037 | inferred from mutant phenotype sperm chromatin decondensation ; GO:0035041 | inferred from mutant phenotype - "wst, wasted" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile,male sterile,recessive" male pronucleus FBgn0070022 BG00829 BG00829 http://flybase.org/reports/FBgn0070022 gene - - - BG00829 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0037433 CG17919 - http://flybase.org/reports/FBgn0037433 protein_coding_gene anion binding ; GO:0043168 | inferred from sequence or structural similarity with HGNC:8630 response to bacterium ; GO:0009617 | inferred from expression pattern multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG17919 "IPR001858:Phosphatidylethanolamine-binding, conserved site, IPR008914:Phosphatidylethanolamine-binding protein" CG17919 11-Aug-17 DroID_v2017_08 "Drer\mrpl38, Drer\pebp1, Drer\pebp4" "Scer\MRPL35, Scer\TFS1, Scer\YLR179C" "Cele\F40A3.3, Cele\Y69E1A.5" "Xtro\pebp4, Xtro\pebp1, Xtro\mrpl38" "Mmus\Pebp1, Mmus\Pebp4, Mmus\Mrpl38, Mmus\Pbp2" "Hsap\PEBP1, Hsap\MRPL38, Hsap\PEBP4" "viable,fertile" DRSC27860 K 0.52523435 -0.239638519 0.773168894 0.257416664 1.889964946 3.35145055 FBgn0031407 CG4270 - http://flybase.org/reports/FBgn0031407 protein_coding_gene - - extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR018244 "BcDNA:AT04879, CG4270" "IPR018244:Allergen V5/Tpx-1-related, conserved site, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR002413:Ves allergen, IPR014044:CAP domain, IPR034113:Golgi-associated plant pathogenesis-related protein 1, SCP domain" CG4270 11-Aug-17 DroID_v2017_08 "Drer\r3hdml, Drer\pi15b, Drer\pi15a, Drer\LOC100536500, Drer\glipr1b, Drer\glipr2, Drer\crispld2, Drer\crispld1b, Drer\glipr2l, Drer\im:7150988, Drer\crispld1a" "Scer\CDC25, Scer\PRY2, Scer\PRY1, Scer\PRY3" "Cele\D2062.1, Cele\F09B9.5, Cele\C07A4.2, Cele\F57B7.2, Cele\W05B10.4, Cele\scl-19, Cele\C07A4.3, Cele\scl-1" "Xtro\crispld2, Xtro\crisp1, Xtro\r3hdml, Xtro\MGC108118, Xtro\glipr2, Xtro\crisp3, Xtro\crisp2" "Mmus\Ralgds, Mmus\Crisp2, Mmus\Pi15, Mmus\Crisp1, Mmus\Pi16, Mmus\Crispld1, Mmus\Crisp4, Mmus\R3hdml, Mmus\Clec18a, Mmus\Crisp3, Mmus\Glipr1l1, Mmus\Glipr2, Mmus\Glipr1l2, Mmus\Glipr1, Mmus\Crispld2" "Hsap\CLEC18C, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\CLEC18B, Hsap\RGL4, Hsap\GLIPR2, Hsap\CRISPLD2, Hsap\RALGDS, Hsap\PI16, Hsap\R3HDML, Hsap\PI15, Hsap\CRISPLD1, Hsap\GLIPR1, Hsap\CLEC18A, Hsap\GLIPR1L2, Hsap\CRISP2" "viable,visible" mesothoracic tergum DRSC00648 K 1.13659701 -0.209719651 0.358052422 -0.053894389 0.467995676 1.568416809 FBgn0020826 l(3)03647 lethal (3) 03647 http://flybase.org/reports/FBgn0020826 - gene - - - l(3)03647 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283509 Phm Peptidylglycine-alpha-hydroxylating monooxygenase http://flybase.org/reports/FBgn0283509 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen ; GO:0016715 | inferred from electronic annotation with InterPro:IPR000323, InterPro:IPR014783, InterPro:IPR014784 copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR000323, InterPro:IPR000720" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000323, InterPro:IPR000720, InterPro:IPR014783, InterPro:IPR014784 peptide metabolic process ; GO:0006518 | inferred from electronic annotation with InterPro:IPR000720 regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern memory ; GO:0007613 | inferred from mutant phenotype response to fungus ; GO:0009620 | inferred from expression pattern" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000720 extracellular space ; GO:0005615 | inferred from direct assay "Phm, PHM, CG3832, dPHM, lance-b, ll" "IPR000323:Copper type II, ascorbate-dependent monooxygenase, N-terminal, IPR000720:Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase, IPR008977:PHM/PNGase F domain, IPR014783:Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site, IPR014784:Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, IPR024548:Copper type II ascorbate-dependent monooxygenase, C-terminal" CG3832 11-Aug-17 DroID_v2017_08 Drer\pam - "Cele\pamn-1, Cele\pgal-1, Cele\pghm-1" Xtro\pam "Mmus\Nhlrc3, Mmus\Pam" "Hsap\NHLRC3, Hsap\PAM" visible "wing,eye,adult head" FBgn0051115 CG31115 - http://flybase.org/reports/FBgn0051115 protein_coding_gene S-methyl-5-thioadenosine phosphorylase activity ; GO:0017061 | inferred from electronic annotation with InterPro:IPR010044 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 - CG31115 "IPR000845:Nucleoside phosphorylase domain, IPR010044:Methylthioadenosine phosphorylase (MTAP)" CG31115 11-Aug-17 DroID_v2017_08 Drer\mtap Scer\MEU1 Cele\B0228.7 Xtro\mtap Mmus\Mtap Hsap\MTAP viable FBgn0265267 CG18258 - http://flybase.org/reports/FBgn0265267 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 molecular_function ; GO:0003674 | no biological data available lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR033906 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT41369, CG18258, anon-SAGE:Wang-051" "IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold, IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin" CG18258 11-Aug-17 DroID_v2017_08 "Drer\lipca, Drer\lipib, Drer\lipg, Drer\pla1a, Drer\lipia, Drer\lpl, Drer\LOC101884800, Drer\LOC100331214" - - "Xtro\lipg, Xtro\lpl" "Mmus\Pnlip, Mmus\Lipi, Mmus\Lipg, Mmus\Liph, Mmus\Pnliprp1, Mmus\Lipc, Mmus\Pnliprp2, Mmus\Lpl, Mmus\Pla1a" "Hsap\LIPH, Hsap\LIPG, Hsap\PLA1A, Hsap\PNLIPRP2, Hsap\LIPI, Hsap\LIPC, Hsap\LPL, Hsap\PNLIPRP1, Hsap\PNLIPRP3, Hsap\PNLIP" FBgn0002069 AspRS Aspartyl-tRNA synthetase http://flybase.org/reports/FBgn0002069 "FBgn0022204, FBgn0025948" protein_coding_gene "aspartate-tRNA ligase activity ; GO:0004815 | inferred from electronic annotation with InterPro:IPR004523 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004364, InterPro:IPR004523, InterPro:IPR018150 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004365 aspartate-tRNA ligase activity ; GO:0004815 | traceable author statement" aspartyl-tRNA aminoacylation ; GO:0006422 | inferred from electronic annotation with InterPro:IPR004523 aspartyl-tRNA aminoacylation ; GO:0006422 | traceable author statement growth ; GO:0040007 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004523 cytoplasm ; GO:0005737 | traceable author statement aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG3821, aats-asp, poney, l(2)49Db, l(2)k04508, AspRS, DRS, cDNA1, vr1, l(2)vr1, clone 2.49, anon-EST:Liang-2.49, l(2)v27, Aats-Asp, Aats-asp" "IPR002312:Aspartyl/Asparaginyl-tRNA synthetase, class IIb, IPR004364:Aminoacyl-tRNA synthetase, class II (D/K/N), IPR004365:OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR004523:Aspartate-tRNA synthetase, type 2, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR012340:Nucleic acid-binding, OB-fold" CG3821 11-Aug-17 DroID_v2017_08 Drer\dars Scer\DPS1 Cele\dars-1 Xtro\dars Mmus\Dars Hsap\DARS embryonic stage "

ubiquitous , embryonic/larval salivary gland

" "lethal,recessive,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,cell autonomous,decreased cell size,somatic clone,wild-type,non-suppressor of variegation,dominant,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective" "wing disc,cell autonomous,somatic clone,wing,embryonic/larval neuroblast,ganglion mother cell" FBgn0034824 Klp59C Kinesin-like protein at 59C http://flybase.org/reports/FBgn0034824 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 motor activity ; GO:0003774 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinetochore microtubule ; GO:0005828 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "KLP59C, DmKLP59C, CG3219, DmKlp59C, DmCG3219, Klp59C, KIF 2B, KIF2A/B/C" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3219 11-Aug-17 DroID_v2017_08 "Drer\zgc:103670, Drer\kif2c" Scer\KIP3 Cele\klp-7 "Xtro\kif2a, Xtro\kif2c" "Mmus\Kif24, Mmus\Kif2c, Mmus\Kif2b, Mmus\Kif2a" "Hsap\KIF24, Hsap\KIF2A, Hsap\KIF2C, Hsap\KIF2B" "mitotic cell cycle defective,viable" "mitosis & nuclear chromosome,microtubule" FBgn0032494 CG5945 - http://flybase.org/reports/FBgn0032494 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CT18564, CG5945, cg5945" IPR010562:Haemolymph juvenile hormone binding CG5945 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265696 CR44503 - http://flybase.org/reports/FBgn0265696 non_protein_coding_gene - - - CR44503 - CR44503 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001943 l(2)26Ad lethal (2) 26Ad http://flybase.org/reports/FBgn0001943 - gene - - - "l(2)gdh-5, l(2)26Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005747 l(1)TK239 lethal (1) TK239 http://flybase.org/reports/FBgn0005747 - gene - - - "l239, l(1)TK239" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0014253 l(2)DA2 lethal (2) DA2 http://flybase.org/reports/FBgn0014253 - gene - - - "DA2, l(2)DA2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036580 PDCD-5 Programmed Cell Death 5 http://flybase.org/reports/FBgn0036580 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002836 molecular_function ; GO:0003674 | no biological data available defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype programmed cell death ; GO:0012501 | inferred from biological aspect of ancestor with PANTHER:PTN000089997 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from sequence or structural similarity with HGNC:8764 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000089996 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000089997 "DMPDCD-5, CG13072, BcDNA:RE17056, PDCD-5, PDCD5" IPR002836:PDCD5-related protein CG13072 11-Aug-17 DroID_v2017_08 Drer\pdcd5 Scer\SDD2 Cele\D2005.3 Xtro\pdcd5 "Mmus\Pdcd5, Mmus\Pdcd5-ps" Hsap\PDCD5 "viable,fertile" DRSC09955 E -0.030048743 -0.079465965 -1.523417301 1.718770224 -0.915957609 -0.348538684 FBgn0014917 anon-72ABa anon-72ABa http://flybase.org/reports/FBgn0014917 - gene - - - anon-72ABa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052110 CG32110 - http://flybase.org/reports/FBgn0052110 protein_coding_gene SUMO-specific protease activity ; GO:0016929 | inferred from sequence or structural similarity with SGD:S000005941 protein desumoylation ; GO:0016926 | inferred from sequence or structural similarity with SGD:S000005941 - "anon-AE003540.1, CG32110" "IPR003653:Ulp1 protease family, C-terminal catalytic domain" CG32110 11-Aug-17 DroID_v2017_08 "Drer\senp3b, Drer\senp5, Drer\senp3a, Drer\senp2, Drer\si:dkey-21c19.3" Scer\ULP1 "Cele\ulp-3, Cele\ulp-2, Cele\ulp-1" - "Mmus\Gm5415, Mmus\Senp1, Mmus\AF366264, Mmus\Gm9839, Mmus\4930444G20Rik, Mmus\Senp2, Mmus\Senp3, Mmus\Senp5" "Hsap\SENP5, Hsap\SENP3, Hsap\SENP2, Hsap\SENP1" viable FBgn0053225 CG33225 - http://flybase.org/reports/FBgn0053225 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" cellular_component ; GO:0005575 | no biological data available CG33225 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG33225 11-Aug-17 DroID_v2017_08 "Drer\habp2, Drer\tmprss4a, Drer\plat" - "Cele\try-1, Cele\try-3" - "Mmus\Tmprss4, Mmus\Egfbp2, Mmus\Plat, Mmus\Habp2, Mmus\Gzmk" "Hsap\TMPRSS4, Hsap\PLAT, Hsap\GZMK, Hsap\HABP2" FBgn0030823 CG8918 - http://flybase.org/reports/FBgn0030823 protein_coding_gene - protein polyglutamylation ; GO:0018095 | inferred from electronic annotation with InterPro:IPR027750 - CG8918 "IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027750:Tubulin polyglutamylase TTLL1" CG8918 11-Aug-17 DroID_v2017_08 "Drer\ttll9, Drer\ttll10, Drer\ttll5, Drer\ttll1, Drer\ttll2, Drer\ttl" Scer\PBY1 "Cele\ttll-9, Cele\ttll-5" "Xtro\ttll3, Xtro\ttl, Xtro\ttll5, Xtro\ttll1, Xtro\ttll2, Xtro\LOC100158544" "Mmus\Ttll5, Mmus\Ttll8, Mmus\Ttll9, Mmus\Ttll1, Mmus\Ttll2, Mmus\Ttll10, Mmus\Ttll3, Mmus\Ttl" "Hsap\TTLL5, Hsap\TTLL8, Hsap\TTLL3, Hsap\TTLL2, Hsap\TTL, Hsap\TTLL10, Hsap\TTLL9, Hsap\TTLL1, Hsap\ARPC4-TTLL3" viable FBgn0002507 l(3)SG68 lethal (3) SG68 http://flybase.org/reports/FBgn0002507 FBgn0004733 gene - - - "l(3)dsl-2, l(3)dsl2, l(3)A2, SG68, l(3)SG68" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0038888 CheB93a Chemosensory protein B 93a http://flybase.org/reports/FBgn0038888 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model "CG15503, CheB93a" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG15503 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267159 CR45599 - http://flybase.org/reports/FBgn0267159 non_protein_coding_gene - - - CR45599 - CR45599 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065831 l(2)SH0349 lethal (2) SH0349 http://flybase.org/reports/FBgn0065831 gene - - - "l(2)SH0349, l(2)SH2 0349" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028664 VhaM9.7-c Vacuolar H[+] ATPase M9.7 subunit c http://flybase.org/reports/FBgn0028664 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from sequence model proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000262636" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model" "proton-transporting V-type ATPase, V0 domain ; GO:0033179 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from biological aspect of ancestor with PANTHER:PTN000262688 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model" "CG11589, vhaM9.7-1, vhaM9.2-1, VhaM9.7-c, vhaM9.7-3, VhaM9.7-1, VhaM9.7-3" "IPR008389:ATPase, V0 complex, subunit e1/e2, IPR017385:ATPase, V0 complex, subunit e1/e2, metazoa" CG11589 11-Aug-17 DroID_v2017_08 "Drer\pars2, Drer\atp6v0e1, Drer\atpv0e2" Scer\VMA9 Cele\vha-17 "Xtro\atp6v0e2, Xtro\atp6v0e1" "Mmus\Atp6v0e, Mmus\Atp6v0e2, Mmus\Pars2" "Hsap\ATP6V0E1, Hsap\ATP6V0E2" "viable,visible" trichogen cell FBgn0260326 GSd243 - http://flybase.org/reports/FBgn0260326 gene - - - GSd243 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,segmental nerve" FBgn0005334 podH podoptera of Hannah http://flybase.org/reports/FBgn0005334 - gene - - - "pod-H, podH" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0260506 Pkc53E::Mmus\Rtkn - http://flybase.org/reports/FBgn0260506 engineered_fusion_gene - - - "Pkc53E::Mmus\Rtkn, Rhot-53E" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084211 W145 W145 http://flybase.org/reports/FBgn0084211 gene - - - W145 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0026352 Su(SuRaf1)A2-1 Su(SuRaf1)A2-1 http://flybase.org/reports/FBgn0026352 - gene - - - "Su[Su(Raf)1]A2-1, Su(SuRaf1)A2-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001647 l(1)dn27 lethal (1) discs normal 27 http://flybase.org/reports/FBgn0001647 - gene - - - "l(1)d.norm.-27, l(1)dn27" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032184 CG13135 - http://flybase.org/reports/FBgn0032184 protein_coding_gene - - - CG13135 - CG13135 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028272 l(1)G0433 lethal (1) G0433 http://flybase.org/reports/FBgn0028272 gene - - - l(1)G0433 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266084 Fhos Formin homology 2 domain containing http://flybase.org/reports/FBgn0266084 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity "muscle system process ; GO:0003012 | inferred from expression pattern inferred from genetic interaction with Mhc positive regulation of substrate adhesion-dependent cell spreading ; GO:1900026 | inferred from mutant phenotype positive regulation of cell migration ; GO:0030335 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of stress fiber assembly ; GO:0051496 | inferred from mutant phenotype inferred from genetic interaction with Rok wound healing, spreading of cells ; GO:0044319 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "Fhos, jaz, CG32030, l(3)01629, CG42610, CG5797, CG5775, dFHOS, CG32025, desert, knit" "IPR014768:Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425:Formin, FH2 domain, IPR014767:Diaphanous autoregulatory (DAD) domain, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG42610 11-Aug-17 DroID_v2017_08 "Drer\fhod1, Drer\fhod3a, Drer\fhod3b" "Scer\BNI1, Scer\BNR1" Cele\fhod-1 "Xtro\fhod1, Xtro\fhod3" "Mmus\Fhod1, Mmus\Fhod3" "Hsap\FHOD3, Hsap\FHOD1" FBgn0036725 CG18265 - http://flybase.org/reports/FBgn0036725 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG18265, ORE-10" IPR013087:Zinc finger C2H2-type CG18265 11-Aug-17 DroID_v2017_08 Drer\znf800a - Cele\die-1 Xtro\znf800 Mmus\Zfp800 Hsap\ZNF91 "viable,fertile" DRSC10310 K -0.541188368 0.480334065 0.344347236 0.138431369 0.807926603 -1.737453188 FBgn0250755 CG42233 - http://flybase.org/reports/FBgn0250755 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42233, CG11574, CG2112" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG42233 11-Aug-17 DroID_v2017_08 Drer\dcaf5 - "Cele\R11D1.1, Cele\adpr-1" - Mmus\Dcaf5 Hsap\DCAF5 FBgn0036365 cmb combover http://flybase.org/reports/FBgn0036365 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with mwh imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with mwh - "NEST:bs28e06, CG10732, cmb" - CG10732 11-Aug-17 DroID_v2017_08 Drer\pcm1 - - Xtro\pcm1 Mmus\Pcm1 Hsap\PCM1 viable FBgn0030266 CG11122 - http://flybase.org/reports/FBgn0030266 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - microtubule associated complex ; GO:0005875 | inferred from direct assay CG11122 "IPR011989:Armadillo-like helical, IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG11122 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,eye" FBgn0015517 ms(2)HB223 male sterile (2) HB223 http://flybase.org/reports/FBgn0015517 - gene - - - ms(2)HB223 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032935 Atg18b Autophagy-related 18b http://flybase.org/reports/FBgn0032935 protein_coding_gene - cellular response to oxidative stress ; GO:0034599 | inferred from direct assay - "l(2)k09410, CG8678, Atg18, Atg18-like, Atg18b, ATG18.2" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG8678 11-Aug-17 DroID_v2017_08 "Drer\wipi2, Drer\LOC100332293, Drer\wipi1" "Scer\ATG18, Scer\ATG21" Cele\atg-18 Xtro\wipi1 "Mmus\Wipi1, Mmus\Wipi2" "Hsap\WIPI2, Hsap\WIPI1" "viable,lethal,recessive" DRSC03108 I 1.70367988 0.85034156 -0.01982464 0.269956615 0.058478325 -0.228434101 FBgn0267606 CR45944 - http://flybase.org/reports/FBgn0267606 non_protein_coding_gene - - - CR45944 - CR45944 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004436 Ubc6 Ubiquitin conjugating enzyme 6 http://flybase.org/reports/FBgn0004436 FBgn0064873 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000003026 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 p53 binding ; GO:0002039 | inferred from physical interaction with p53 ubiquitin conjugating enzyme activity ; GO:0061631 | inferred by curator from GO:0042787 protein domain specific binding ; GO:0019904 | inferred from physical interaction with UniProtKB:Q8IMZ4 "DNA repair ; GO:0006281 | inferred from genetic interaction with SGD:S000003026 negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype negative regulation of DNA damage response, signal transduction by p53 class mediator ; GO:0043518 | inferred from mutant phenotype negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ; GO:1902166 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 centrosome organization ; GO:0051297 | inferred from mutant phenotype centrosome separation ; GO:0051299 | inferred from mutant phenotype histone ubiquitination ; GO:0016574 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype" HULC complex ; GO:0033503 | inferred from biological aspect of ancestor with PANTHER:PTN000630652 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000630652 cytoplasm ; GO:0005737 | inferred from direct assay "RAD6, Rad6, Dhr6, CG2013, BcDNA:RE56673, UbcD6, Rad6a, dRad6, dRAD6, Ubc6, UBC6" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG2013 11-Aug-17 DroID_v2017_08 "Drer\ube2al, Drer\ube2a, Drer\ube2b" Scer\RAD6 Cele\ubc-1 "Xtro\ube2b, Xtro\ube2a" "Mmus\Ube2u, Mmus\Ube2b, Mmus\Ube2a" "Hsap\UBE2A, Hsap\UBE2B, Hsap\UBE2U" "lethal - all die before end of larval stage,recessive,neurophysiology defective,increased cell death,lethal,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuromuscular junction,mitochondrion | third instar larval stage,wing" DRSC12370 IEK -1.746964077 -1.14141391 -1.544899447 -1.01139816 1.898146923 -0.48485935 FBgn0065561 l(2)SH0991 lethal (2) SH0991 http://flybase.org/reports/FBgn0065561 gene - - - "l(2)SH0991, l(2)SH2 0991" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029859 CG15892 - http://flybase.org/reports/FBgn0029859 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32918, CG15892" - CG15892 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0060332 l(3)S145613 lethal (3) S145613 http://flybase.org/reports/FBgn0060332 gene - - - "1456/13, l(3)S145613" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266327 CR44992 - http://flybase.org/reports/FBgn0266327 non_protein_coding_gene - - - CR44992 - CR44992 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046639 anon-38D.6 anon-38D.6 http://flybase.org/reports/FBgn0046639 gene - - - "38D.6, anon-38D.6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000437 df defective http://flybase.org/reports/FBgn0000437 - gene - - - df - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority live" "ocellar bristle,interocellar bristle" FBgn0058045 CG40045 - http://flybase.org/reports/FBgn0058045 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12482 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12482 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000629793 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000629793 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "BcDNA:RE63412, CG40045" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG40045 11-Aug-17 DroID_v2017_08 "Drer\cdc34b, Drer\ube2r2, Drer\ube2g1b, Drer\ube2g1a, Drer\ube2g2, Drer\cdc34a" "Scer\CDC34, Scer\UBC7" "Cele\ubc-7, Cele\ubc-14" "Xtro\ube2g2, Xtro\ube2r2, Xtro\ube2g1, Xtro\cdc34" "Mmus\Ube2r2, Mmus\Ube2g1, Mmus\Ube2g2, Mmus\Cdc34" "Hsap\UBE2R2, Hsap\UBE2G1, Hsap\UBE2G2, Hsap\CDC34" DRSC21232 K -0.034833707 0.168078986 0.215030145 0.277643187 0.371501906 2.233570939 FBgn0261839 pre-mod(mdg4)-Y - http://flybase.org/reports/FBgn0261839 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-Y, CG42771, RY" "IPR007588:Zinc finger, FLYWCH-type" CG42771 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050155 tRNA:Trp-CCA-1-1 transfer RNA:Tryptophan-CCA 1-1 http://flybase.org/reports/FBgn0050155 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "AE002787.trna60-TrpCCA, tRNA:W:CCA:AE002787-c, CR30155, chr2R.trna44-TrpCCA, tRNA-Trp-CCA-1-1, tRNA:Trp-CCA-1-1, tRNA:CR30155, UGG" - CR30155 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034986 mRpS17 mitochondrial ribosomal protein S17 http://flybase.org/reports/FBgn0034986 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R5 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R5 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R5 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R5 "MRP-S17, CG4326, mRpS17" "IPR012340:Nucleic acid-binding, OB-fold, IPR000266:Ribosomal protein S17/S11" CG4326 11-Aug-17 DroID_v2017_08 Drer\mrps17 - Cele\mrps-17 Xtro\mrps17 Mmus\Mrps17 Hsap\MRPS17 viable DRSC04463 E -1.234529304 0.007542804 -1.769462037 0.157535672 0.1234868 0.917702378 FBgn0043527 anon-AE003814.3 anon-AE003814.3 http://flybase.org/reports/FBgn0043527 gene - - - anon-AE003814.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015302 Su(SD)3A Suppressor of SD 3A http://flybase.org/reports/FBgn0015302 - gene - - - Su(SD)3A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261452 scaRNA:MeU2-G25 small Cajal body-specific RNA : MeU2-G25 http://flybase.org/reports/FBgn0261452 snoRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "mgU2-25, scaRNA:mask-a, scaRNA:mgU2-25, scaRNA:MeU2-G25" - CR43569 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011642 Zyx Zyxin http://flybase.org/reports/FBgn0011642 "FBgn0047225, FBgn0052018" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 protein binding ; GO:0005515 | inferred from physical interaction with ena "cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with HGNC:13200 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype chitin-based cuticle sclerotization ; GO:0007593 | inferred from mutant phenotype hippo signaling ; GO:0035329 | inferred from mutant phenotype imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype positive regulation of organ growth ; GO:0046622 | inferred from mutant phenotype positive regulation of eclosion ; GO:0045805 | inferred from mutant phenotype" cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity stress fiber ; GO:0001725 | inferred from direct assay cell-cell junction ; GO:0005911 | inferred from sequence or structural similarity with HGNC:13200 focal adhesion ; GO:0005925 | inferred from sequence or structural similarity with HGNC:13200 subapical complex ; GO:0035003 | inferred from direct assay "CG32018, BcDNA:LD06023, zyx102, zyxin, ZYX102, lim, Zyxin, Zyx102, DmLIM-1, Lim102EF, DLim-1, Zyx102EF, Zyx, zyx" "IPR001781:Zinc finger, LIM-type" CG32018 11-Aug-17 DroID_v2017_08 "Drer\trip6, Drer\limd1b, Drer\ajuba, Drer\wtip, Drer\lpp, Drer\fblim1, Drer\zyx, Drer\limd1a" Scer\LRG1 Cele\zyx-1 Xtro\lpp "Mmus\Limd1, Mmus\Trip6, Mmus\Wtip, Mmus\Zyx, Mmus\Fblim1, Mmus\Lpp, Mmus\Ajuba" "Hsap\ZYX, Hsap\TRIP6, Hsap\WTIP, Hsap\LPP, Hsap\FBLIM1, Hsap\LIMD1, Hsap\AJUBA" "viable,locomotor behavior defective,eclosion defective,lethal - all die before end of P-stage,some die during pharate adult stage,fertile,size defective" "wing,adult abdomen,adult cuticle,adult trachea,tracheole,crossvein,ectopic" FBgn0033307 CG14752 - http://flybase.org/reports/FBgn0033307 protein_coding_gene - - - CG14752 - CG14752 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051395 CG31395 - http://flybase.org/reports/FBgn0051395 protein_coding_gene - - - CG31395 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040690 CG13899 - http://flybase.org/reports/FBgn0040690 protein_coding_gene - - - CG13899 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039451 CG6420 - http://flybase.org/reports/FBgn0039451 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein deubiquitination ; GO:0016579 | inferred from biological aspect of ancestor with PANTHER:PTN000364080 cellular_component ; GO:0005575 | no biological data available CG6420 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG6420 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000000529, Drer\wdr20" - Cele\wdr-20 Xtro\wdr20 "Mmus\Wdr20, Mmus\Dmwd, Mmus\Wdr20rt" "Hsap\WDR20, Hsap\DMWD" "viable,fertile" DRSC16035 K -0.39426711 0.241122906 -0.656145642 0.678835876 2.117854079 0.720366585 FBgn0012041 Atn Allatotropin http://flybase.org/reports/FBgn0012041 - gene hormone activity ; GO:0005179 | non-traceable author statement - - Atn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051211 CG31211 - http://flybase.org/reports/FBgn0051211 protein_coding_gene - - - "CG14732, CG18546, cDNA, anon-WO03070958.3, CG31211" IPR031937:PNN-interacting serine/arginine-rich protein CG31211 11-Aug-17 DroID_v2017_08 Drer\pnisr - Cele\rsy-1 Xtro\pnisr Mmus\Pnisr Hsap\PNISR viable FBgn0030475 CG15748 - http://flybase.org/reports/FBgn0030475 protein_coding_gene - - - CG15748 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001446 l(1)7Ch lethal (1) 7Ch http://flybase.org/reports/FBgn0001446 - gene - - - l(1)7Ch - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267508 28SrRNA-Psi:CR45848 28S ribosomal RNA pseudogene:CR45848 http://flybase.org/reports/FBgn0267508 pseudogene_attribute - - - "28SrRNA-Psi:CR45848, CR45848" - CR45848 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082959 snoRNA:Psi28S-3405b snoRNA:Psi28S-3405b http://flybase.org/reports/FBgn0082959 snoRNA_gene - - - "snoRNA:Psi28S-3405b, psi28s-3405b, CR34620" - CR34620 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052250 PMP34 Peroxisomal Membrane Protein 34 http://flybase.org/reports/FBgn0052250 protein_coding_gene FMN transmembrane transporter activity ; GO:0044610 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 AMP transmembrane transporter activity ; GO:0080122 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 ATP transmembrane transporter activity ; GO:0005347 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 FAD transmembrane transporter activity ; GO:0015230 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 NAD transporter activity ; GO:0051724 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 coenzyme A transmembrane transporter activity ; GO:0015228 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 ADP transmembrane transporter activity ; GO:0015217 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 nucleoside transport ; GO:0015858 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:10987 integral component of peroxisomal membrane ; GO:0005779 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 "CG1326, BcDNA:RE36975, PMP34, dPMP34, CG32250" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG32250 11-Aug-17 DroID_v2017_08 "Drer\LOC566378, Drer\slc25a17" "Scer\YEA6, Scer\ANT1, Scer\YIA6" - Xtro\slc25a17 Mmus\Slc25a17 Hsap\SLC25A17 viable FBgn0001189 hfw halfway http://flybase.org/reports/FBgn0001189 FBgn0023532 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to ecdysone ; GO:0035075 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype - "swi, CG3095, EG:171E4.2, SWI, CT10406, l(1)nfw, l(1)2Bf, hfw" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG3095 11-Aug-17 DroID_v2017_08 "Drer\aspn, Drer\si:ch211-237i5.4" - "Cele\lron-2, Cele\slt-1, Cele\lron-1" "Xtro\vasn, Xtro\islr2" "Mmus\Aspn, Mmus\Islr2" Hsap\ISLR2 "viable,reduced,visible,recessive,lethal,male,lethal - all die before end of pupal stage,some die during pupal stage" "wing,adult abdomen" FBgn0024860 l(3)96Bb lethal (3) 96Bb http://flybase.org/reports/FBgn0024860 - gene - - - l(3)96Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034643 CG10321 - http://flybase.org/reports/FBgn0034643 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG10321 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG10321 11-Aug-17 DroID_v2017_08 "Drer\znf827, Drer\znf513, Drer\zbtb40" Scer\AZF1 Cele\klf-3 Xtro\zbtb40 "Mmus\Zfp827, Mmus\Zbtb40, Mmus\Zfp513" "Hsap\ZBTB40, Hsap\ZNF841, Hsap\ZNF836, Hsap\ZNF827, Hsap\ZNF513, Hsap\OSR2" viable FBgn0021811 l(2)k16525 lethal (2) k16525 http://flybase.org/reports/FBgn0021811 - gene - - - l(2)k16525 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039210 CG13625 - http://flybase.org/reports/FBgn0039210 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:28199 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "anon-WO0118547.376, CG13625" IPR018609:Bud13 CG13625 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-69c1.6, Drer\casc3" Scer\BUD13 Cele\R08D7.1 "Xtro\bud13, Xtro\casc3" "Mmus\Bud13, Mmus\Casc3" "Hsap\BUD13, Hsap\CASC3" FBgn0005172 l(2)G583 lethal (2) G583 http://flybase.org/reports/FBgn0005172 - gene - - - l(2)G583 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037018 CG4042 - http://flybase.org/reports/FBgn0037018 protein_coding_gene - - - CG4042 "IPR032675:Leucine-rich repeat domain, L domain-like" CG4042 11-Aug-17 DroID_v2017_08 Drer\si:ch1073-228b5.2 - "Cele\Y53G8AR.8, Cele\C05C8.1" "Xtro\atp5s, Xtro\atp5sl" "Mmus\Atp5sl, Mmus\Atp5s" "Hsap\ATP5SL, Hsap\ATP5S" viable FBgn0032312 CG14071 - http://flybase.org/reports/FBgn0032312 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cell cycle ; GO:0051726 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available CG14071 - CG14071 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002848 msg missing http://flybase.org/reports/FBgn0002848 - gene - - - "ms, msg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female sterile,male fertile,poor" macrochaeta FBgn0000798 fs(1)de9 female sterile (1) defective eggs 9 http://flybase.org/reports/FBgn0000798 - gene - - - "de9, fs(1)de9" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "endochorion,dorsal appendage,chorion" FBgn0004097 l(2)60De lethal (2) 60De http://flybase.org/reports/FBgn0004097 - gene - - - l(2)60De - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible" FBgn0026740 anon-64Ca anon-64Ca http://flybase.org/reports/FBgn0026740 - gene - - - "gene b, anon-64Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011043 l(1)Stark-b lethal (1) of Stark b http://flybase.org/reports/FBgn0011043 FBgn0010212 gene - - - "l(1)Stark-b, l(1)Sb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260047 33AC1 - http://flybase.org/reports/FBgn0260047 gene - - - 33AC1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0065204 l(2)SH2285 lethal (2) SH2285 http://flybase.org/reports/FBgn0065204 gene - - - "l(2)SH2285, l(2)SH2 2285" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034883 Eglp2 Entomoglyceroporin 2 http://flybase.org/reports/FBgn0034883 protein_coding_gene water channel activity ; GO:0015250 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 channel activity ; GO:0015267 | inferred from sequence or structural similarity with Drip ion transmembrane transport ; GO:0034220 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 renal system process ; GO:0003014 | inferred from expression pattern transmembrane transport ; GO:0055085 | inferred from sequence or structural similarity with Drip integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Drip integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 "CG17664, Aqp17664, Eglp2, Eglp 2" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR022357:Major intrinsic protein, conserved site, IPR023271:Aquaporin-like" CG17664 11-Aug-17 DroID_v2017_08 "Drer\aqp7, Drer\aqp9b, Drer\mipa, Drer\mipb, Drer\aqp1a.1, Drer\aqp8a.1, Drer\aqp1a.2, Drer\aqp10a, Drer\aqp3a, Drer\aqp8a.2, Drer\aqp4, Drer\aqp8b" "Scer\AQY1, Scer\AQY2, Scer\YFL054C, Scer\FPS1, Scer\YLL053C" "Cele\aqp-2, Cele\aqp-4, Cele\aqp-7, Cele\aqp-6, Cele\aqp-5, Cele\aqp-8, Cele\aqp-12, Cele\aqp-3" "Xtro\LOC100216133, Xtro\mip, Xtro\aqp2, Xtro\aqp5" "Mmus\Aqp3, Mmus\Aqp5, Mmus\Aqp4, Mmus\Aqp1, Mmus\Aqp2, Mmus\Aqp8, Mmus\Mip, Mmus\Aqp7, Mmus\Aqp6, Mmus\Aqp9" "Hsap\AQP10, Hsap\MIP, Hsap\AQP4, Hsap\AQP8, Hsap\AQP3, Hsap\AQP2, Hsap\AQP1, Hsap\AQP6, Hsap\AQP9, Hsap\AQP7, Hsap\AQP5" "viable,visible,lethal" trichogen cell FBgn0262189 mir-2500 mir-2500 stem loop http://flybase.org/reports/FBgn0262189 miRNA_gene - - - "dme-mir-2500, mir-2500, CR42896, miR-2500" - CR42896 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014848 Eig71Eh Eig71Eh http://flybase.org/reports/FBgn0014848 - protein_coding_gene - defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 metamorphosis ; GO:0007552 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model "L71, CG7594, L71-8, Eig71Eh, EIG71-H" IPR003475:Insect protein of unknown function CG7594 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001294 jyx jaunty-x http://flybase.org/reports/FBgn0001294 - gene - - - jyx - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced,visible" FBgn0266247 CR44942 - http://flybase.org/reports/FBgn0266247 non_protein_coding_gene - - - "CR44942, lincRNA.759" - CR44942 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259653 B0538 - http://flybase.org/reports/FBgn0259653 gene - - - B0538 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing sensillum,ectopic,wing margin bristle,leg,distal" FBgn0025490 l(3)82EFa lethal (3) 82EFa http://flybase.org/reports/FBgn0025490 - gene - - - l(3)82EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035871 BI-1 Bax Inhibitor-1 http://flybase.org/reports/FBgn0035871 protein_coding_gene endoribonuclease inhibitor activity ; GO:0060698 | inferred from sequence or structural similarity with UniProtKB:P55061 negative regulation of apoptotic process ; GO:0043066 | inferred from electronic annotation with InterPro:IPR006213 negative regulation of cell death ; GO:0060548 | inferred from direct assay negative regulation of endoribonuclease activity ; GO:0060702 | inferred from direct assay negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype negative regulation of endoplasmic reticulum unfolded protein response ; GO:1900102 | inferred from sequence or structural similarity with HGNC:11723 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response ; GO:1904721 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006213 integral component of membrane ; GO:0016021 | inferred from sequence model protein complex ; GO:0043234 | inferred from sequence or structural similarity with HGNC:11723 "CG7188, d-BI-1, dTmbim6, BI-1, dBI-1" "IPR006213:Bax inhibitor 1, conserved site, IPR006214:Bax inhibitor 1-related" CG7188 11-Aug-17 DroID_v2017_08 Drer\tegt - Cele\K11H12.8 Xtro\tmbim6 Mmus\Tmbim6 Hsap\TMBIM6 "viable,fertile,starvation stress response defective,long lived,nutrition conditional,short lived,chemical conditional" "embryonic/larval salivary gland | pupal stage,lysosome | nutrition conditionalda.G32,fat body,nutrition conditional,autophagic vacuole | nutrition conditionalda.G32" FBgn0053408 5SrRNA:CR33408 5SrRNA:CR33408 http://flybase.org/reports/FBgn0053408 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33408, 5SrRNA:CR33408" - CR33408 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041589 l(3)S136802 lethal (3) S136802 http://flybase.org/reports/FBgn0041589 gene - - - "1368.02, l(3)S136802" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" presumptive embryonic/larval nervous system FBgn0028973 yew yew http://flybase.org/reports/FBgn0028973 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - yew - - 11-Aug-17 DroID_v2017_08 - - - - - - "dendrite | dorsal | embryonic stage,presumptive embryonic/larval peripheral nervous system,dorsal" FBgn0067787 anon-i118 anon-i118 http://flybase.org/reports/FBgn0067787 gene - - - "i118, anon-i118" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053767 CG33767 - http://flybase.org/reports/FBgn0053767 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14458, CG33767" IPR010512:Protein of unknown function DUF1091 CG33767 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024734 PRL-1 PRL-1 phosphatase http://flybase.org/reports/FBgn0024734 "FBgn0027875, FBgn0062445" protein_coding_gene protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340 protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with RGD:61970 prenylated protein tyrosine phosphatase activity ; GO:0004727 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | inferred from biological aspect of ancestor with PANTHER:PTN000596945 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein dephosphorylation ; GO:0006470 | non-traceable author statement peptidyl-tyrosine dephosphorylation ; GO:0035335 | inferred from sequence or structural similarity with RGD:61970 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000596947 cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "PRL, CG4993, BG:DS07473.3, BcDNA:RE40268, PRL-1, PrL-1, dPRL-1, PRL1" "IPR000387:Tyrosine specific protein phosphatases domain, IPR029021:Protein-tyrosine phosphatase-like, IPR000340:Dual specificity phosphatase, catalytic domain" CG4993 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-251p5.5, Drer\ptp4a1, Drer\ptp4a2b, Drer\ptp4a2a, Drer\ptp4a3" - Cele\T19D2.2 "Xtro\ptp4a3, Xtro\ptp4a1, Xtro\ptp4a2" "Mmus\Ptp4a1, Mmus\Ptp4a2, Mmus\Ptp4a3" "Hsap\PTP4A2, Hsap\PTP4A3, Hsap\PTP4A1" "viable,fertile,size defective,somatic clone,hypoplasia,lethal - all die before end of larval stage,majority die during first instar larval stage,wild-type,partially lethal - majority die,recessive" "wing,eye,somatic clone,head capsule,wing disc" DRSC27332 IK 3.596079543 0.235626341 0.769394229 0.342403053 0.316581321 1.766985396 FBgn0067360 l(2)NC83 lethal (2) NC83 http://flybase.org/reports/FBgn0067360 gene - - - "NC83, l(2)NC83" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0070036 3R-69-15 3R-69-15 http://flybase.org/reports/FBgn0070036 gene molecular_function ; GO:0003674 | no biological data available oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-69-15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg,germline clone,maternal effect,dorsal appendage,non-rescuable maternal effect" FBgn0067060 P307 P307 http://flybase.org/reports/FBgn0067060 gene - - - P307 - - 11-Aug-17 DroID_v2017_08 - - - - - - neurophysiology defective FBgn0013636 l(4)ry1 lethal (4) ry1 http://flybase.org/reports/FBgn0013636 - gene - - - "l(4)1, l(4)ry1" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0045971 PdL75A3 PdL75A3 http://flybase.org/reports/FBgn0045971 gene - - - PdL75A3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265178 CG44243 - http://flybase.org/reports/FBgn0265178 protein_coding_gene lipoyltransferase activity ; GO:0017118 | inferred from sequence or structural similarity with UniProtKB:Q9HKT1 lipoate-protein ligase activity ; GO:0016979 | inferred from biological aspect of ancestor with PANTHER:PTN000285675 protein lipoylation ; GO:0009249 | inferred from biological aspect of ancestor with PANTHER:PTN000285675 protein lipoylation ; GO:0009249 | inferred from sequence or structural similarity with UniProtKB:Q9HKT1 cellular_component ; GO:0005575 | no biological data available "CG44243, CG8446" "IPR004143:Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain, IPR004562:Lipoyltransferase/lipoate-protein ligase" CG44243 11-Aug-17 DroID_v2017_08 "Drer\lipt1, Drer\mrps36" Scer\AIM22 Cele\C45G3.3 "Xtro\mrps36, Xtro\lipt1" "Mmus\Lipt1, Mmus\Mrps36" Hsap\LIPT1 FBgn0060978 l(3)S028705b lethal (3) S028705b http://flybase.org/reports/FBgn0060978 gene - - - "0287/05, l(3)S028705b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065281 l(2)SH2031 lethal (2) SH2031 http://flybase.org/reports/FBgn0065281 gene - - - "l(2)SH2031, l(2)SH2 2031" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265733 CR44540 - http://flybase.org/reports/FBgn0265733 non_protein_coding_gene - - - CR44540 - CR44540 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035470 Ccz1 "Caffeine, calcium, zinc sensitivity 1" http://flybase.org/reports/FBgn0035470 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000000335 endosome to lysosome transport via multivesicular body sorting pathway ; GO:0032510 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | inferred from biological aspect of ancestor with PANTHER:PTN000316458 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with SGD:S000000335 autophagy ; GO:0006914 | inferred from sequence or structural similarity with SGD:S000000335 vesicle ; GO:0031982 | inferred from biological aspect of ancestor with PANTHER:PTN000316458 Mon1-Ccz1 complex ; GO:0035658 | inferred from sequence or structural similarity with SGD:S000000335 cytosol ; GO:0005829 | inferred from direct assay "CG14980, Ccz1, Dccz1, C7orf28B, NP_647835" "IPR013176:Protein of unknown function DUF1712, fungi" CG14980 11-Aug-17 DroID_v2017_08 Drer\ccz1 - Cele\ccz-1 Xtro\ccz1b Mmus\Ccz1 "Hsap\CCZ1B, Hsap\CCZ1" "viable,fertile" endosomeptc-559.1 FBgn0029685 CG2938 - http://flybase.org/reports/FBgn0029685 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG2938 IPR012419:Cas1p 10 TM acyl transferase domain CG2938 11-Aug-17 DroID_v2017_08 Drer\casd1 - - Xtro\casd1 Mmus\Casd1 Hsap\CASD1 "viable,visible,body color defective" "chaeta,mesothoracic tergum" FBgn0023181 Orc4 Origin recognition complex subunit 4 http://flybase.org/reports/FBgn0023181 - protein_coding_gene DNA replication origin binding ; GO:0003688 | inferred from biological aspect of ancestor with PANTHER:PTN000250139 DNA replication initiation ; GO:0006270 | inferred from direct assay nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay "rDmORC, ORC4, orc4, ORC, DmORC4, CG2917, Orc4, dmOrc4" "IPR003593:AAA+ ATPase domain, IPR016527:Origin recognition complex subunit 4, IPR032705:Origin recognition complex subunit 4, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2917 11-Aug-17 DroID_v2017_08 Drer\orc4 Scer\ORC4 - Xtro\orc4 Mmus\Orc4 Hsap\ORC4 embryonic stage && larval stage "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0015928 dfc defaced http://flybase.org/reports/FBgn0015928 - gene - - - dfc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" "mouth hooks,lateral process,dorsal bridge" FBgn0267577 CR45917 - http://flybase.org/reports/FBgn0267577 non_protein_coding_gene - - - "CR45917, pri-mir-92b" - CR45917 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032422 atilla atilla http://flybase.org/reports/FBgn0032422 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6579, atilla" - CG6579 11-Aug-17 DroID_v2017_08 - - "Cele\C15H9.9, Cele\K11H12.7, Cele\K11H12.6" - - - "viable,fertile" FBgn0000627 Eyl Eyeluf http://flybase.org/reports/FBgn0000627 - gene - - - Eyl - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,antenna" FBgn0035155 RabX6 RabX6 http://flybase.org/reports/FBgn0035155 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" lipid particle organization ; GO:0034389 | inferred from biological aspect of ancestor with PANTHER:PTN000756441 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 neuronal cell body ; GO:0043025 | inferred from direct assay "RabX6, CG12015, DmRabX6, rabx6, rabX6" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12015 11-Aug-17 DroID_v2017_08 "Drer\rab2a, Drer\rab18a, Drer\LOC100330257, Drer\dnajc27, Drer\rab18b" Scer\YPT7 Cele\rab-18 "Xtro\rab2a, Xtro\rab39a, Xtro\rab2b, Xtro\dnajc27" "Mmus\Rab2b, Mmus\Rab18, Mmus\Dnajc27, Mmus\Rab2a, Mmus\Agap1, Mmus\Rab42" "Hsap\RAB18, Hsap\AGAP1, Hsap\AGAP4, Hsap\RAB2B, Hsap\RAB2A, Hsap\DNAJC27" "partially lethal - majority die,some die during pupal stage" FBgn0030944 CG6617 - http://flybase.org/reports/FBgn0030944 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey180, CG6617" "IPR024964:CTLH/CRA C-terminal to LisH motif domain, IPR006594:LIS1 homology motif, IPR006595:CTLH, C-terminal LisH motif, IPR013144:CRA domain" CG6617 11-Aug-17 DroID_v2017_08 "Drer\gid8b, Drer\gid8a" Scer\GID8 Cele\tag-304 Xtro\gid8 Mmus\Gid8 Hsap\GID8 FBgn0060433 l(3)S125414b lethal (3) S125414b http://flybase.org/reports/FBgn0060433 gene - - - "1254/14, l(3)S125414b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265993 CR44768 - http://flybase.org/reports/FBgn0265993 non_protein_coding_gene - - - "CR44768, lincRNA.186" - CR44768 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001747 l(1)HM19 lethal (1) HM19 http://flybase.org/reports/FBgn0001747 - gene - - - l(1)HM19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive" FBgn0025809 Paf-AHalpha Platelet-activating factor acetylhydrolase alpha http://flybase.org/reports/FBgn0025809 - protein_coding_gene 1-alkyl-2-acetylglycerophosphocholine esterase activity ; GO:0003847 | NOT inferred from direct assay - - "AAC83820, PAFAHalpha, CG8962, Paf-AHalpha, Dmaalpha[[PAFAH]]" IPR013830:SGNH hydrolase-type esterase domain CG8962 11-Aug-17 DroID_v2017_08 "Drer\ice1, Drer\pafah1b3, Drer\pafah1b2" - - "Xtro\pafah1b2, Xtro\pafah1b3" "Mmus\Ice1, Mmus\Pafah1b3, Mmus\Pafah1b2" "Hsap\PAFAH1B2, Hsap\PAFAH1B3, Hsap\ICE1" viable FBgn0003877 tu(2)48j tumor(2)48j http://flybase.org/reports/FBgn0003877 - gene - - - "tu-48j, tu(2)48j" - - 11-Aug-17 DroID_v2017_08 - - - - - - melanotic mass phenotype FBgn0028407 Drep3 DNA fragmentation factor-related protein 3 http://flybase.org/reports/FBgn0028407 protein_coding_gene - regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000959605 neurogenesis ; GO:0022008 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003508 "drep3, BcDNA:AT08574, CG13187, CG8364, Drep-3, Drep3, DREP-3, Rep3, drep-3" IPR003508:CIDE-N domain CG8364 11-Aug-17 DroID_v2017_08 "Drer\cidec, Drer\dffa, Drer\cidea, Drer\cideb" - - "Xtro\cidea, Xtro\cidec, Xtro\cideb" "Mmus\Cideb, Mmus\Cidec, Mmus\Cidea, Mmus\Dffa" "Hsap\CIDEB, Hsap\CIDEA, Hsap\CIDEC, Hsap\DFFA" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0261629 CG42712 - http://flybase.org/reports/FBgn0261629 protein_coding_gene - - - CG42712 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029893 CG14442 - http://flybase.org/reports/FBgn0029893 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG14442 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR023753:FAD/NAD(P)-binding domain" CG14442 11-Aug-17 DroID_v2017_08 - - Cele\C05D11.13 Xtro\znf821 Mmus\Zfp821 Hsap\ZNF821 "viable,fertile,visible" mesothoracic tergum FBgn0013434 btd::Mmmm\Sp1 btd::Mmmm\Sp1 http://flybase.org/reports/FBgn0013434 - engineered_fusion_gene - - - "btd::mammal\Sp1, btd::Mmmm\Sp1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265799 CR44588 - http://flybase.org/reports/FBgn0265799 non_protein_coding_gene - - - CR44588 - CR44588 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069417 JJF137 JJF137 http://flybase.org/reports/FBgn0069417 gene - - - JJF137 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0264392 CR43840 - http://flybase.org/reports/FBgn0264392 non_protein_coding_gene - - - CR43840 - CR43840 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053435 5SrRNA:CR33435 5SrRNA:CR33435 http://flybase.org/reports/FBgn0053435 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33435, 5SrRNA:CR33435" - CR33435 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016058 rtg rotated genitalia http://flybase.org/reports/FBgn0016058 - gene - - - rtg - - 11-Aug-17 DroID_v2017_08 - - - - - - visible genitalia FBgn0264605 CG43954 - http://flybase.org/reports/FBgn0264605 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from sequence model CG43954 - CG43954 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265493 BG01887 - http://flybase.org/reports/FBgn0265493 gene - - - BG01887 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262227 mir-991 mir-991 stem loop http://flybase.org/reports/FBgn0262227 miRNA_gene - - - "dme-mir-991, mir-991, CR42934, miR-991" - CR42934 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052485 CG32485 - http://flybase.org/reports/FBgn0052485 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2 - Golgi apparatus ; GO:0005794 | inferred from direct assay "CG2159, CG32485" "IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG32485 11-Aug-17 DroID_v2017_08 Drer\mospd2 "Scer\PDR17, Scer\PDR16, Scer\CSR1" "Cele\T03F7.7, Cele\hpo-28, Cele\C34C12.6" - Mmus\Mospd2 Hsap\MOSPD2 viable FBgn0259918 inaF-B inaF-B http://flybase.org/reports/FBgn0259918 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with trp calcium channel regulator activity ; GO:0005246 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from mutant phenotype regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from mutant phenotype rhabdomere ; GO:0016028 | inferred from direct assay inaD signaling complex ; GO:0016027 | inferred from physical interaction with inaD inferred from physical interaction with trp rhabdomere membrane ; GO:0033583 | inferred from direct assay "inaF-B, CG42447, inaF, INAF, InaF, INAF-B" "IPR029162:TRP-interacting helix, InaF motif" CG42447 11-Aug-17 DroID_v2017_08 - - - - - - neurophysiology defective photoreceptor cell FBgn0262908 sax::Agam\sax - http://flybase.org/reports/FBgn0262908 engineered_fusion_gene - - - sax::Agam\sax - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001434 l(1)7Ad lethal (1) 7Ad http://flybase.org/reports/FBgn0001434 - gene - - - "l(1)jnR4, jnR4, l(1)7Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "genitalia,male,wing,wing disc,mesothoracic leg disc" FBgn0035247 metl methyltransferase-like http://flybase.org/reports/FBgn0035247 protein_coding_gene S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from sequence or structural similarity with EMBL:BC006985 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey109, CG13929, metl" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR026113:Methyltransferase-like" CG13929 11-Aug-17 DroID_v2017_08 "Drer\mettl6, Drer\mettl8, Drer\mettl2a" Scer\ABP140 "Cele\ZK1058.5, Cele\metl-2" "Xtro\mettl2b, Xtro\mettl6" "Mmus\Mettl2, Mmus\Mettl6, Mmus\Mettl8" "Hsap\METTL2A, Hsap\METTL2B, Hsap\METTL8, Hsap\METTL6" "wild-type,viable" FBgn0051438 CheB93b Chemosensory protein B 93b http://flybase.org/reports/FBgn0051438 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CG31438, CheB93b" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG31438 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0062442 Cisd2 CDGSH iron sulfur domain 2 http://flybase.org/reports/FBgn0062442 protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR006622, InterPro:IPR018967, InterPro:IPR019610 molecular_function ; GO:0003674 | no biological data available" biological_process ; GO:0008150 | no biological data available "intracellular membrane-bounded organelle ; GO:0043231 | inferred from electronic annotation with InterPro:IPR006622, InterPro:IPR018967, InterPro:IPR019610 cellular_component ; GO:0005575 | no biological data available" "BcDNA:RE49709, CG1458, MitoNEET, Cisd2, cisd2, dWFS2" "IPR018967:Iron sulphur-containing domain, CDGSH-type, IPR019610:Iron sulphur domain-containing, mitoNEET, N-terminal" CG1458 11-Aug-17 DroID_v2017_08 "Drer\zgc:110843, Drer\cisd2, Drer\cisd1" - Cele\cisd-1 "Xtro\cisd2, Xtro\cisd1" "Mmus\Cisd1, Mmus\Cisd2" "Hsap\CISD2, Hsap\CISD1" viable FBgn0266210 CR44905 - http://flybase.org/reports/FBgn0266210 non_protein_coding_gene - - - CR44905 - CR44905 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041756 eth-as314 eth-as314 http://flybase.org/reports/FBgn0041756 gene - - - "eth[as]314, eth-as314" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0028391 anon-50ABc anon-50ABc http://flybase.org/reports/FBgn0028391 gene - - - "C, anon-50ABc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027182 l(2)60A-L lethal (2) 60A-L http://flybase.org/reports/FBgn0027182 - gene - - - l(2)60A-L - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053178 CG33178 - http://flybase.org/reports/FBgn0053178 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from sequence or structural similarity with MGI:MGI:1913850 glutathione metabolic process ; GO:0006749 | inferred from sequence or structural similarity with MGI:MGI:1913850 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:1913850 "CG5579, BcDNA:RH14671, CG33178" "IPR001129:Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein, IPR023352:Membrane associated eicosanoid/glutathione metabolism-like domain" CG33178 11-Aug-17 DroID_v2017_08 "Drer\mgst1.1, Drer\mgst1.2, Drer\ptges" - - "Xtro\mgst1, Xtro\ptges" "Mmus\Ptges, Mmus\Mgst1" "Hsap\PTGES, Hsap\MGST1" viable FBgn0013269 FK506-bp1 FK506-binding protein 1 http://flybase.org/reports/FBgn0013269 - protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR026257 juvenile hormone response element binding ; GO:0070594 | inferred from direct assay FK506 binding ; GO:0005528 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Chd64 histone peptidyl-prolyl isomerization ; GO:0000412 | inferred from electronic annotation with InterPro:IPR026257 negative regulation of macroautophagy ; GO:0016242 | inferred from mutant phenotype negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype juvenile hormone mediated signaling pathway ; GO:0035626 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from electronic annotation with InterPro:IPR026257 microtubule associated complex ; GO:0005875 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay "IFK506-bp1, CG6226, FK506bp1, FKBP39, FKbp39, FK506-bp1" "IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR026257:FK506-binding protein" CG6226 11-Aug-17 DroID_v2017_08 "Drer\fkbp1ab, Drer\fkbp11, Drer\fkbp1b, Drer\fkbp9, Drer\fkbp10b, Drer\fkbp14, Drer\fkbp1aa, Drer\fkbp2, Drer\fkbp7, Drer\fkbp10a, Drer\si:ch73-199g24.2, Drer\si:ch211-208h16.4" "Scer\FPR4, Scer\FPR3" "Cele\fkb-3, Cele\fkb-2, Cele\fkb-5, Cele\fkb-4" "Xtro\fkbp14, Xtro\fkbp7, Xtro\fkbp3, Xtro\fkbp1b, Xtro\fkbp9, Xtro\fkbp15, Xtro\fkbp10" "Mmus\Fkbp3, Mmus\Fkbp2, Mmus\Fkbp11, Mmus\Fkbp14, Mmus\Fkbp1a, Mmus\Fkbp15, Mmus\Fkbp1b, Mmus\Fkbp10, Mmus\Fkbp7, Mmus\Fkbp9" "Hsap\FKBP15, Hsap\FKBP7, Hsap\FKBP11, Hsap\FKBP9, Hsap\FKBP10, Hsap\FKBP1B, Hsap\FKBP2, Hsap\FKBP3, Hsap\FKBP14" " embryonic stage -- adult stage , adult stage && oogenesis stage , adult stage " " ovary

,

ubiquitous " "visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "embryonic/larval fat body,somatic clone,trichogen cell,mesothoracic tergum" DRSC16667 EK 1.201663215 0.791282378 1.69799848 -0.397210135 2.584880987 0.550019966 FBgn0266619 CR45126 - http://flybase.org/reports/FBgn0266619 non_protein_coding_gene - - - CR45126 - CR45126 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264678 CR43963 - http://flybase.org/reports/FBgn0264678 non_protein_coding_gene - - - CR43963 - CR43963 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065647 l(2)SH0749 lethal (2) SH0749 http://flybase.org/reports/FBgn0065647 gene - - - "l(2)SH0749, l(2)SH2 0749" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069912 CR40474 - http://flybase.org/reports/FBgn0069912 non_protein_coding_gene - - - CR40474 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005191 l(2)S51 lethal of Seto 51 http://flybase.org/reports/FBgn0005191 - gene - - - l(2)S51 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" FBgn0020932 Est-B Est-B http://flybase.org/reports/FBgn0020932 - gene - - - Est-B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000023 acclinal-wing acclinal wing http://flybase.org/reports/FBgn0000023 - gene - - - "acc, acclinal-wing" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,good,fertile,flightless" wing FBgn0041129 l(2)45Ag lethal (2) 45Ag http://flybase.org/reports/FBgn0041129 gene - - - l(2)45Ag - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0259710 CG42364 - http://flybase.org/reports/FBgn0259710 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15675, CG42364" - CG42364 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052212 CG32212 - http://flybase.org/reports/FBgn0052212 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32212 - CG32212 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060980 l(3)S028401 lethal (3) S028401 http://flybase.org/reports/FBgn0060980 gene - - - "0284/01, l(3)S028401" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001828 l(1)TS56 lethal (1) TS56 http://flybase.org/reports/FBgn0001828 - gene - - - "l(1)TS-56, l(1)TS56" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval tracheal system,embryonic segment" FBgn0025616 CG13359 - http://flybase.org/reports/FBgn0025616 - protein_coding_gene - - - "EG:34F3.9, CG13359" "IPR032675:Leucine-rich repeat domain, L domain-like" CG13359 11-Aug-17 DroID_v2017_08 - Scer\MSC1 "Cele\dur-1, Cele\lea-1" - - Hsap\EFCAB13 viable FBgn0031940 CG7214 - http://flybase.org/reports/FBgn0031940 protein_coding_gene - positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype - CG7214 IPR031874:Adult cuticle protein 1 CG7214 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC03028 IEK 1.479609521 -2.499599158 1.555861842 1.444557231 1.885904257 0.032893018 FBgn0015766 Msr-110 Msr-110 http://flybase.org/reports/FBgn0015766 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from sequence model "CG10596, Msr-110" IPR022207:Genetic suppressor element-like CG10596 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 11 , embryonic stage | stage 11 | late , embryonic stage | 12-18 hr , embryonic stage | stage 11 | early , larval stage " " embryonic/larval pharynx

, inclusive hindgut primordium

, median tooth

, posterior spiracle primordium

, anal pad | presumptive

, stomodeum

, antenno-maxillary complex | presumptive

, imaginal disc

, epidermis

" viable FBgn0037412 Osi4 Osiris 4 http://flybase.org/reports/FBgn0037412 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi4, CG10303" IPR012464:Protein of unknown function DUF1676 CG10303 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023530 CG3740 - http://flybase.org/reports/FBgn0023530 - protein_coding_gene - neuromuscular process ; GO:0050905 | inferred from genetic interaction with CG11671 - "EG:171E4.4, CG3740" IPR033369:Protein C19orf12 homologue CG3740 11-Aug-17 DroID_v2017_08 "Drer\zgc:101715, Drer\si:ch211-260e23.7, Drer\zgc:112052, Drer\si:ch211-260e23.8" - - Xtro\c19orf12 Mmus\1600014C10Rik Hsap\C19orf12 viable FBgn0058317 CG40317 - http://flybase.org/reports/FBgn0058317 protein_coding_gene - - - CG40317 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263355 CG31688 - http://flybase.org/reports/FBgn0263355 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31688, CG11019, 38C.52, 38C.49, CG18597, CG11017, CG11016, CG31688-PA" IPR001602:Uncharacterised protein family UPF0047 CG31688 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266008 CR44781 - http://flybase.org/reports/FBgn0266008 non_protein_coding_gene - - - CR44781 - CR44781 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020858 fj-s four-jointed-similis http://flybase.org/reports/FBgn0020858 - gene - - - fj-s - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267120 CR45560 - http://flybase.org/reports/FBgn0267120 non_protein_coding_gene - - - CR45560 - CR45560 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024509 Sec13 Secretory 13 http://flybase.org/reports/FBgn0024509 "FBgn0025715, FBgn0027897" protein_coding_gene structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity with SGD:S000004198 chromatin binding ; GO:0003682 | inferred from direct assay inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype ecdysone-mediated polytene chromosome puffing ; GO:0035077 | inferred from direct assay larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from direct assay COPII-coated vesicle budding ; GO:0090114 | inferred from sequence or structural similarity with SGD:S000004198 NLS-bearing protein import into nucleus ; GO:0006607 | NOT inferred from mutant phenotype positive regulation of transcription initiation from RNA polymerase II promoter ; GO:0060261 | inferred from mutant phenotype cellular response to heat ; GO:0034605 | inferred from mutant phenotype chromatin ; GO:0000785 | inferred from direct assay inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay GATOR2 complex ; GO:0061700 | traceable author statement COPII vesicle coat ; GO:0030127 | inferred from sequence or structural similarity with SGD:S000004198 nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with HGNC:10697 Seh1-associated complex ; GO:0035859 | inferred from direct assay Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000004198 "Dsec13, l(3)01031, CK00043, CG6773, BcDNA:LD03471, BEST:CK00043, SEC13, Sec13, sec13" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat" CG6773 11-Aug-17 DroID_v2017_08 Drer\sec13 Scer\SEC13 Cele\npp-20 Xtro\sec13 Mmus\Sec13 Hsap\SEC13 "lethal,recessive" FBgn0024623 l(4)102Ca lethal (4) 102Ca http://flybase.org/reports/FBgn0024623 - gene - - - l(4)102Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060929 l(3)S042016b lethal (3) S042016b http://flybase.org/reports/FBgn0060929 gene - - - "0420/16, l(3)S042016b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265870 CR44659 - http://flybase.org/reports/FBgn0265870 non_protein_coding_gene - - - CR44659 - CR44659 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026727 chs chaos http://flybase.org/reports/FBgn0026727 - gene - - - chs - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic/larval central nervous system,commissure,longitudinal connective" FBgn0036470 EAChm Enhancer of Acetyltransferase Chameau http://flybase.org/reports/FBgn0036470 protein_coding_gene histone acetyltransferase regulator activity ; GO:0035034 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype histone H3 acetylation ; GO:0043966 | inferred from direct assay" - "BcDNA:RE10167, CG13463, EAChm" - CG13463 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011048 l(1)Q1 lethal (1) Q1 http://flybase.org/reports/FBgn0011048 FBgn0010210 gene - - - l(1)Q1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0050197 CG30197 - http://flybase.org/reports/FBgn0050197 protein_coding_gene peptidase inhibitor activity ; GO:0030414 | inferred from electronic annotation with InterPro:IPR008197 biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR008197 "BcDNA:RE05231, CG30197" IPR008197:WAP-type 'four-disulfide core' domain CG30197 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004038 yea4 yeast 4 http://flybase.org/reports/FBgn0004038 - gene - - - yea4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003335 Scn Scutenick http://flybase.org/reports/FBgn0003335 - gene - - - Scn - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "scutellar bristle,ocellus,macrochaeta,eye,cold sensitive,scutellum" FBgn0036230 CG11570 - http://flybase.org/reports/FBgn0036230 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG11570, mlncRNA68E3" IPR002557:Chitin binding domain CG11570 11-Aug-17 DroID_v2017_08 - - Cele\dct-9 - - - "viable,fertile" FBgn0026161 tiz tiziano http://flybase.org/reports/FBgn0026161 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available tiz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037815 Rrp46 Rrp46 http://flybase.org/reports/FBgn0037815 protein_coding_gene - "polyadenylation-dependent snoRNA 3'-end processing ; GO:0071051 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype rRNA 3'-end processing ; GO:0031125 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' ; GO:0034427 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 nuclear mRNA surveillance ; GO:0071028 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 U4 snRNA 3'-end processing ; GO:0034475 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 rRNA catabolic process ; GO:0016075 | inferred from biological aspect of ancestor with PANTHER:PTN000237327" cytoplasm ; GO:0005737 | inferred from direct assay nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000003327 inferred from direct assay cytoplasmic exosome (RNase complex) ; GO:0000177 | inferred from biological aspect of ancestor with PANTHER:PTN000237328 exosome (RNase complex) ; GO:0000178 | inferred from direct assay nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 "CG4043, dRrp46, Rrp46, rrp46" "IPR015847:Exoribonuclease, phosphorolytic domain 2, IPR001247:Exoribonuclease, phosphorolytic domain 1, IPR027408:PNPase/RNase PH domain, IPR020568:Ribosomal protein S5 domain 2-type fold" CG4043 11-Aug-17 DroID_v2017_08 Drer\exosc5 Scer\RRP46 Cele\crn-5 Xtro\exosc5 Mmus\Exosc5 Hsap\EXOSC5 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0015441 l(1)6DEa lethal (1) 6DEa http://flybase.org/reports/FBgn0015441 - gene - - - l(1)6DEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037099 CG7173 - http://flybase.org/reports/FBgn0037099 protein_coding_gene - - - CG7173 "IPR002350:Kazal domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7173 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000778 fs(1)A1371 female sterile (1) A1371 http://flybase.org/reports/FBgn0000778 - gene - - - "fs(1)1371, fs(1)A1371" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,female sterile,recessive,heat sensitive,non-rescuable maternal effect" "blastoderm embryo,gastrula embryo" FBgn0015932 dsRNABP6 ds-RNA binding protein 6 http://flybase.org/reports/FBgn0015932 - gene - - - "dsRNABP#6, dsRNABP6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259335 EP-M89 - http://flybase.org/reports/FBgn0259335 gene - - - EP-M89 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,wing,chaeta" FBgn0060338 l(3)S144507a lethal (3) S144507a http://flybase.org/reports/FBgn0060338 gene - - - "1445/07, l(3)S144507a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262126 Sec24CD Secretory 24CD http://flybase.org/reports/FBgn0262126 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006895 "positive regulation of extracellular matrix constituent secretion ; GO:0003331 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype cargo loading into COPII-coated vesicle ; GO:0090110 | inferred from sequence or structural similarity with SGD:S000001371 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein localization to cell surface ; GO:0034394 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype protein targeting to plasma membrane ; GO:0072661 | inferred from mutant phenotype basement membrane organization ; GO:0071711 | inferred from mutant phenotype maintenance of cell polarity ; GO:0030011 | inferred from mutant phenotype regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype positive regulation of cuticle pigmentation ; GO:0048081 | inferred from mutant phenotype" COPII vesicle coat ; GO:0030127 | inferred from sequence or structural similarity with SGD:S000001371 endoplasmic reticulum exit site ; GO:0070971 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG10882, Sec24, Sec24CD, sten, BcDNA:LP05220, FBgn0031408, gho, sfb3, sec24, Sten" "IPR002035:von Willebrand factor, type A, IPR029006:ADF-H/Gelsolin-like domain, IPR006895:Zinc finger, Sec23/Sec24-type, IPR006896:Sec23/Sec24, trunk domain, IPR006900:Sec23/Sec24, helical domain, IPR007123:Gelsolin-like domain, IPR012990:Sec23/Sec24 beta-sandwich" CG10882 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-13n15.2, Drer\sec24c, Drer\sec24d" "Scer\SFB2, Scer\SFB3, Scer\SEC24" Cele\sec-24.1 Xtro\sec24d "Mmus\Sec24d, Mmus\Sec24c" "Hsap\SEC24C, Hsap\SEC24D" FBgn0061500 l(2)44Fp lethal (2) 44Fp http://flybase.org/reports/FBgn0061500 gene - - - "l(2)44Fk, l(2)44Fp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267887 CR46175 - http://flybase.org/reports/FBgn0267887 pseudogene_attribute - - - "CR46175, CG12717-related" - CR46175 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262387 mir-190 mir-190 stem loop http://flybase.org/reports/FBgn0262387 miRNA_gene - muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-190, mir-190, miR-190, MIR-190, CR42915, dme-miR-190" - CR42915 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "eye,wing,wing margin,wing vein,1st posterior cell" FBgn0267760 CR46091 - http://flybase.org/reports/FBgn0267760 non_protein_coding_gene - - - CR46091 - CR46091 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082622 S(CycE[JP])42S33 S(CycE[JP])42S33 http://flybase.org/reports/FBgn0082622 gene - - - "42S33, S(CycE[JP])42S33" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0001380 l(1)2Bl lethal (1) 2Bl http://flybase.org/reports/FBgn0001380 - gene - - - l(1)2Bl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0040812 CG8750 - http://flybase.org/reports/FBgn0040812 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8750 - CG8750 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005522 l(2)52Db lethal (2) 52Db http://flybase.org/reports/FBgn0005522 - gene - - - l(2)52Db - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031453 Bacc Bacchus http://flybase.org/reports/FBgn0031453 protein_coding_gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CG9894, clone 2.54, anon-EST:Liang-2.54, Bacc" - CG9894 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant,viable,behavior defective,recessive,partially lethal - majority die,fertile" FBgn0001349 l(1)1Ed lethal (1) 1Ed http://flybase.org/reports/FBgn0001349 - gene - - - l(1)1Ed - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0042213 CG18731 - http://flybase.org/reports/FBgn0042213 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18731 IPR028227:Uncharacterised protein family UPF0449 CG18731 11-Aug-17 DroID_v2017_08 Drer\si:ch73-238c9.1 - - Xtro\c19orf25 Mmus\2310011J03Rik Hsap\C19orf25 viable DRSC15377 K 0.122779763 1.181857024 -0.310698265 -0.210586874 0.689266881 1.872992678 FBgn0001467 l(1)7Fd lethal (1) 7Fd http://flybase.org/reports/FBgn0001467 - gene - - - "l(1)VA67, l(1)7Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0266868 CR45329 - http://flybase.org/reports/FBgn0266868 non_protein_coding_gene - - - CR45329 - CR45329 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011976 tRNA:Ser-CGA-1-2 transfer RNA:Serine-CGA 1-2 http://flybase.org/reports/FBgn0011976 "FBgn0003826, FBgn0011968, FBgn0011973, FBgn0052623, FBgn0060062" tRNA_gene UCG codon-amino acid adaptor activity ; GO:0033408 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033408 cytosol ; GO:0005829 | inferred by curator from GO:0033408 "444-2, Ser-tRNA-4, tRNA-Ser, tRNA[Ser], Ser tRNA[Ser], AE002593.trna3-SerCGA, tRNA:S:CGA:AE002593-b, CR32623, tRNA:ser, tRNA:S, tRNA:ser4, tRNA:S4, tRNA:ser4:12Eb, tRNA[[Ser]], chrX.trna7-SerCGA, tRNA-Ser-CGA-1-2, tRNA:Ser-CGA-1-2, tRNA:S4:12Eb, UCG" - CR32623 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028540 CG9008 - http://flybase.org/reports/FBgn0028540 protein_coding_gene "isomerase activity ; GO:0016853 | inferred from electronic annotation with InterPro:IPR008183 carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR008183, InterPro:IPR011013, InterPro:IPR014718 Golgi organization ; GO:0007030 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype" - "BG:DS00797.2, CG9008" "IPR025532:Glucose-6-phosphate 1-epimerase, IPR008183:Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013:Galactose mutarotase-like domain, IPR014718:Glycoside hydrolase-type carbohydrate-binding" CG9008 11-Aug-17 DroID_v2017_08 - Scer\YMR099C - - - - "lethal,visible,body color defective,partially lethal - majority die,some die during pupal stage" "microchaeta & mesothoracic tergum‘±Tub84B.PL,trichogen cell,mesothoracic tergum" FBgn0264738 CG43996 - http://flybase.org/reports/FBgn0264738 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43996, CG12433" - CG43996 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036923 CG17732 - http://flybase.org/reports/FBgn0036923 protein_coding_gene - - - CG17732 - CG17732 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265210 ninaE::Btau\RHO - http://flybase.org/reports/FBgn0265210 engineered_fusion_gene - - - ninaE::Btau\RHO - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266798 CR45260 - http://flybase.org/reports/FBgn0266798 non_protein_coding_gene - - - CR45260 - CR45260 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062611 Mod(var)1310 Mod(var)1310 http://flybase.org/reports/FBgn0062611 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1310, Mod(var)1310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0016841 l(1)N1 lethal (1) N1 http://flybase.org/reports/FBgn0016841 - gene - - - "l(1)N1, N1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003512 Sry-delta Serendipity delta http://flybase.org/reports/FBgn0003512 FBgn0014946 protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" "bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype inferred from genetic interaction with bcd oogenesis ; GO:0048477 | inferred from genetic interaction with bcd positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay "srydelta, sry-delta, sry, EH8, Sry delta, Sry-delta, sry delta, Srydelta, anon-EH8, CG17958" IPR013087:Zinc finger C2H2-type CG17958 11-Aug-17 DroID_v2017_08 "Drer\zgc:171551, Drer\znf1051, Drer\si:dkey-237m9.1, Drer\si:dkey-261j4.4, Drer\im:7141269, Drer\znf1069, Drer\si:dkeyp-113d7.1, Drer\znf1136, Drer\si:dkey-261j4.5, Drer\zgc:113209, Drer\znf1007, Drer\znf1059, Drer\si:ch73-367f21.6, Drer\LOC100537687, Drer\drl, Drer\zgc:173714, Drer\zgc:174646, Drer\LOC100151333, Drer\LOC108183935, Drer\znf1070, Drer\znf1041, Drer\znf1078, Drer\si:dkey-261j4.3" - Cele\sdz-12 - - "Hsap\GZF1, Hsap\ZNF200, Hsap\ZNF449" " adult stage && oogenesis stage | stage >S10B , oogenesis stage | stage , nurse cell

, organism

" " embryonic stage | stage 12-17 , embryonic stage | stage >5 , embryonic stage | stage <5 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S>12 " " embryonic/larval pharynx

,

, nurse cell

, ventral nerve cord

, supraesophageal ganglion

, oocyte , follicle cell

" "wild-type,lethal,recessive,partially" "testis,embryonic/first instar larval cuticle,embryonic/first instar larval cuticle & thoracic segment,telson,posterior,gonad,male,spermatozoon,cephalopharyngeal skeleton" FBgn0038113 CG11668 - http://flybase.org/reports/FBgn0038113 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP115, CG11668" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11668 11-Aug-17 DroID_v2017_08 Drer\f10 - "Cele\try-1, Cele\svh-1" - Mmus\F9 "Hsap\F10, Hsap\MASP1, Hsap\PROC, Hsap\F7" viable FBgn0262734 eIF4H1 eukaryotic translation initiation factor 4H1 http://flybase.org/reports/FBgn0262734 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity ribosomal small subunit binding ; GO:0043024 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 RNA strand annealing activity ; GO:0033592 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 RNA strand-exchange activity ; GO:0034057 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity formation of translation preinitiation complex ; GO:0001731 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 eukaryotic translation initiation factor 4F complex assembly ; GO:0097010 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 translational initiation ; GO:0006413 | inferred from sequence or structural similarity cytoplasmic translation ; GO:0002181 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity "Rbp2, eIF4H, cg4429, CG4429, RRM2, rrm2, anon-EST:fe1B9, MRE9, eIF4H1" "IPR034229:eIF4H, RNA recognition motif, IPR000504:RNA recognition motif domain" CG4429 11-Aug-17 DroID_v2017_08 "Drer\hnrnpabb, Drer\ncoa5, Drer\eif4ba, Drer\raly, Drer\hnrnpd, Drer\zgc:55733, Drer\hnrnpaba, Drer\trnau1apb, Drer\cirbpa, Drer\hnrnpa3, Drer\hnrnpc, Drer\trnau1apa, Drer\srsf10a, Drer\eif4h, Drer\rbm34, Drer\zcrb1, Drer\hnrnpa1b, Drer\wu:fq32h04, Drer\eif4bb, Drer\dazl" "Scer\MRN1, Scer\NAB6, Scer\NOP6, Scer\MUD1, Scer\NGR1, Scer\TIF3, Scer\NOP12, Scer\CWC2, Scer\NAM8" "Cele\H05C05.1, Cele\drr-2" "Xtro\dazl, Xtro\cirbp, Xtro\raly, Xtro\hnrnpa2b1, Xtro\trnau1ap, Xtro\hnrnpdl, Xtro\hnrnpa1, Xtro\hnrnpab, Xtro\eif4b, Xtro\rbm34, Xtro\hnrnpc, Xtro\ralyl, Xtro\hnrnpa3, Xtro\hnrnpd, Xtro\eif4h" "Mmus\Eif4b, Mmus\Hnrnpd, Mmus\Srsf10, Mmus\Zcrb1, Mmus\Slirp, Mmus\Trnau1ap, Mmus\Gm21379, Mmus\Hnrnpab, Mmus\Hnrnpc, Mmus\Hnrnpa1, Mmus\Rbm34, Mmus\Raly, Mmus\Cirbp, Mmus\Eif4h, Mmus\Hnrnpa3, Mmus\Tra2b, Mmus\Boll, Mmus\Dazl, Mmus\Rbm31y, Mmus\Hnrnpa2b1, Mmus\Srsf12" "Hsap\DAZ4, Hsap\SRSF10, Hsap\EIF4B, Hsap\CIRBP, Hsap\RALY, Hsap\DAZ2, Hsap\HNRNPCL1, Hsap\DAZ1, Hsap\DAZ3, Hsap\EIF4H, Hsap\HNRNPD, Hsap\HNRNPA2B1, Hsap\RBM3, Hsap\RBM34, Hsap\HNRNPA1, Hsap\RALYL, Hsap\HNRNPA1L2, Hsap\HNRNPA3, Hsap\DAZL, Hsap\HNRNPAB, Hsap\TRNAU1AP, Hsap\SLIRP, Hsap\HNRNPC, Hsap\BOLL" FBgn0259855 Su(Ste):CR42424 Su(Ste):CR42424 http://flybase.org/reports/FBgn0259855 non_protein_coding_gene - - - "Su(Ste):CR42424, CR42424" - CR42424 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267889 CR46177 - http://flybase.org/reports/FBgn0267889 pseudogene_attribute - - - CR46177 - CR46177 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017386 l(1)15De lethal (1) 15De http://flybase.org/reports/FBgn0017386 - gene - - - l(1)15De - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003633 Su(var)327 Suppressor of variegation 327 http://flybase.org/reports/FBgn0003633 - gene - - - "Su(var)327, 327" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0030915 CG6179 - http://flybase.org/reports/FBgn0030915 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:17946 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000316766 "negative regulation of catalytic activity ; GO:0043086 | inferred from sequence or structural similarity with UniProtKB:Q9Y314 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013 protein ubiquitination ; GO:0016567 | inferred from biological aspect of ancestor with PANTHER:PTN000316766 negative regulation of nitric-oxide synthase activity ; GO:0051001 | inferred from sequence or structural similarity with UniProtKB:Q9Y314" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9Y314 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9Y314 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG6179, NOSIPL" "IPR016818:Nitric oxide synthase-interacting, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR031790:Nitric oxide synthase-interacting protein, zinc-finger" CG6179 11-Aug-17 DroID_v2017_08 Drer\nosip - Cele\R05G6.4 Xtro\nosip Mmus\Nosip Hsap\NOSIP "viable,fertile" FBgn0002271 l(3)69Bc lethal (3) 69Bc http://flybase.org/reports/FBgn0002271 - gene - - - "rsg33, l(3)rsg33, l(3)69Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052076 Alg10 Alpha 3 glucosyltransferase http://flybase.org/reports/FBgn0052076 protein_coding_gene dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity ; GO:0004583 | inferred from electronic annotation with InterPro:IPR016900 dolichol-linked oligosaccharide biosynthetic process ; GO:0006488 | inferred from electronic annotation with InterPro:IPR016900 endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR016900 "Alg10, CG32076, CG7624, alg10, dAlg10" IPR016900:Alpha-2-glucosyltransferase Alg10 CG32076 11-Aug-17 DroID_v2017_08 Drer\alg10 Scer\DIE2 Cele\tag-179 Xtro\alg10 Mmus\Alg10b "Hsap\ALG10, Hsap\ALG10B" FBgn0039237 CG13640 - http://flybase.org/reports/FBgn0039237 protein_coding_gene - - - "BcDNA:RE70528, CG13640" - CG13640 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0030673 CG15601 - http://flybase.org/reports/FBgn0030673 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15601 IPR006578:MADF domain CG15601 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19670 K -0.05866301 0.335403336 -0.049939983 0.56349732 -0.115180018 1.602430298 FBgn0015682 elav::Dvir\elav elav::Dvir\elav http://flybase.org/reports/FBgn0015682 - engineered_fusion_gene - - - elav::Dvir\elav - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,sterile" FBgn0026666 MagR Magnetic receptor http://flybase.org/reports/FBgn0026666 "FBgn0030677, FBgn0063708" protein_coding_gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR016092 structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR016092 protein maturation by iron-sulfur cluster transfer ; GO:0097428 | inferred from electronic annotation with InterPro:IPR016092 response to magnetism ; GO:0071000 | inferred from direct assay - "CG8198, BcDNA:AT26381, l(1)G0136, MagR, dMagR" "IPR000361:FeS cluster biogenesis, IPR016092:FeS cluster insertion protein, IPR017870:FeS cluster insertion, C-terminal, conserved site" CG8198 11-Aug-17 DroID_v2017_08 Drer\isca1 Scer\ISA1 Cele\Y39B6A.3 Xtro\isca1 Mmus\Isca1 Hsap\ISCA1 "lethal,recessive,locomotor rhythm defective" DRSC20092 IK -0.358861444 -1.540499237 -0.490274825 0.13959556 2.862034549 -0.133821632 FBgn0050440 CG30440 - http://flybase.org/reports/FBgn0050440 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with trio positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with trio cellular_component ; GO:0005575 | no biological data available "CG10412, CG12183, CG10416, CG30440" "IPR000219:Dbl homology (DH) domain, IPR001331:Guanine-nucleotide dissociation stimulator, CDC24, conserved site, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG30440 11-Aug-17 DroID_v2017_08 "Drer\arhgef25b, Drer\plekhg4, Drer\LOC559907, Drer\LOC569231, Drer\zgc:158766, Drer\mcf2a, Drer\quo, Drer\mcf2la, Drer\mcf2l2, Drer\arhgef40, Drer\si:dkey-65j6.2, Drer\kalrnb" Scer\CDC24 "Cele\cgef-1, Cele\unc-73" "Xtro\arhgef40, Xtro\kalrn, Xtro\mcf2, Xtro\mcf2l" "Mmus\Arhgef40, Mmus\Mcf2l, Mmus\Mcf2, Mmus\Plekhg4, Mmus\D630003M21Rik" "Hsap\PLEKHG4B, Hsap\MCF2, Hsap\MCF2L2, Hsap\PLEKHG4, Hsap\MCF2L, Hsap\ARHGEF40, Hsap\KALRN" viable FBgn0024675 l(2)k00313 lethal (2) k00313 http://flybase.org/reports/FBgn0024675 - gene - - - "3/13, l(2)k00313" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039448 TwdlQ TweedleQ http://flybase.org/reports/FBgn0039448 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlQ, CG14250" IPR004145:Domain of unknown function DUF243 CG14250 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0028046 l(3)S096901b lethal (3) S096901b http://flybase.org/reports/FBgn0028046 gene - - - "0969/01, l(3)S096901, l(3)S096901b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051496 CG31496 - http://flybase.org/reports/FBgn0051496 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG14604, CG31496" - CG31496 11-Aug-17 DroID_v2017_08 "Drer\zgc:153681, Drer\nxf1" Scer\MEX67 - Xtro\nxf1 "Mmus\Nxf1, Mmus\Nxf7, Mmus\Nxf2, Mmus\Nxf3" "Hsap\NXF5, Hsap\NXF3, Hsap\NXF1, Hsap\NXF2B, Hsap\NXF2" viable FBgn0051051 CG31051 - http://flybase.org/reports/FBgn0051051 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT3186, CG1540, CG31051" - CG31051 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC15034 E -0.112870161 0.915641129 0.359011628 1.623710019 0.425581888 0.435726266 FBgn0086057 snoRNA:Me28S-G2017 - http://flybase.org/reports/FBgn0086057 snoRNA_gene - - - "snoRNA:Me28S-G2017, Me28S-Gm2017, Me28S-C2017, CR34686" - CR34686 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259474 EP-738 - http://flybase.org/reports/FBgn0259474 gene - - - EP-738 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein L3 FBgn0263950 BG00817 - http://flybase.org/reports/FBgn0263950 gene - - - BG00817 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective" FBgn0026778 Rad1 Radiation insensitive 1 http://flybase.org/reports/FBgn0026778 - protein_coding_gene 3'-5' exonuclease activity ; GO:0008408 | inferred from biological aspect of ancestor with PANTHER:PTN000853143 damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000093171 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000093171 DNA damage checkpoint ; GO:0000077 | inferred from biological aspect of ancestor with PANTHER:PTN000093171 checkpoint clamp complex ; GO:0030896 | inferred from direct assay "Rad1[Dm], CG3240, Rad1, Dromel_CG3240_FBtr0077747_rad1_mORF, rad1, DmRad1" "IPR003011:Cell cycle checkpoint protein, Rad1, IPR003021:Rad1/Rec1/Rad17" CG3240 11-Aug-17 DroID_v2017_08 Drer\rad1 Scer\RAD17 Cele\mrt-2 Xtro\rad1 Mmus\Rad1 Hsap\RAD1 "viable,fertile" FBgn0001720 l(1)ESHS41 lethal (1) ESHS41 http://flybase.org/reports/FBgn0001720 - gene - - - l(1)ESHS41 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086301 mace mace http://flybase.org/reports/FBgn0086301 gene - filopodium assembly ; GO:0046847 | inferred from mutant phenotype - mace - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal,recessive" "dendrite | larval stage,dorsal multidendritic neuron ddaA & filopodium" FBgn0085195 CG34166 - http://flybase.org/reports/FBgn0085195 protein_coding_gene - - - "CG34166, CG15281" - CG34166 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028195 l(3)S022348 lethal (3) S022348 http://flybase.org/reports/FBgn0028195 gene - - - "0223/48, l(3)S022348" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035375 pgant6 polypeptide GalNAc transferase 6 http://flybase.org/reports/FBgn0035375 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG2103, pgant6, Pgant6" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG2103 11-Aug-17 DroID_v2017_08 "Drer\galnt10, Drer\galnt16, Drer\LOC101882942, Drer\galnt6, Drer\galnt12, Drer\LOC100535692, Drer\LOC568645, Drer\galnt2, Drer\galnt9, Drer\galnt18b, Drer\wbscr17, Drer\poc1bl, Drer\LOC103910015, Drer\galnt1, Drer\galnt8b, Drer\si:ch211-15e22.3, Drer\LOC101886587, Drer\galnt3, Drer\galnt7, Drer\LOC100334784, Drer\galnt13, Drer\galnt14, Drer\galnt8a.1, Drer\galnt11" - "Cele\gly-11, Cele\gly-10, Cele\gly-7, Cele\gly-9, Cele\gly-3" "Xtro\wbscr17, Xtro\galnt2, Xtro\galnt15, Xtro\galnt9, Xtro\galnt4, Xtro\galnt16, Xtro\galnt1, Xtro\galnt7, Xtro\galnt13, Xtro\galnt14, Xtro\galnt10, Xtro\galnt6.1, Xtro\galnt12" "Mmus\Galnt3, Mmus\Galnt12, Mmus\Galnt13, Mmus\Galnt15, Mmus\Galnt16, Mmus\Galntl5, Mmus\Galntl6, Mmus\Galnt5, Mmus\Wbscr17, Mmus\Galnt7, Mmus\Galnt18, Mmus\Galnt14, Mmus\Galnt11, Mmus\Galnt4, Mmus\Galnt1, Mmus\Galnt9, Mmus\Galnt6, Mmus\Galnt2, Mmus\Galnt10" "Hsap\GALNT7, Hsap\GALNT18, Hsap\GALNTL5, Hsap\GALNT16, Hsap\GALNT5, Hsap\GALNT14, Hsap\GALNT6, Hsap\GALNT10, Hsap\GALNT11, Hsap\GALNTL6, Hsap\GALNT9, Hsap\GALNT4, Hsap\GALNT1, Hsap\GALNT3, Hsap\GALNT8, Hsap\GALNT15, Hsap\GALNT12, Hsap\GALNT2, Hsap\POC1B-GALNT4, Hsap\GALNT13, Hsap\WBSCR17" "viable,fertile,partially lethal - majority die" DRSC26927 K -0.127862827 -0.704383345 1.214036843 0.174381164 -0.643245135 1.533963867 FBgn0067758 l(1)G0029 lethal (1) G0029 http://flybase.org/reports/FBgn0067758 gene - - - l(1)G0029 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0027655 htt huntingtin http://flybase.org/reports/FBgn0027655 - protein_coding_gene - axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG9995, dhtt, HD, Htt, htt, HTT, dHtt, DmHtt" "IPR016024:Armadillo-type fold, IPR024613:Huntingtin, middle-repeat, IPR028426:Huntingtin family, IPR011989:Armadillo-like helical" CG9995 11-Aug-17 DroID_v2017_08 Drer\htt - Cele\F21G4.6 Xtro\htt Mmus\Htt Hsap\HTT "viable,fertile,short lived,visible,progressive,neuroanatomy defective,sleep defective" "axon | larval stageAppl.G1a,embryonic/larval brain,eye,ommatidium,progressive" FBgn0019872 l(3)96Ab lethal (3) 96Ab http://flybase.org/reports/FBgn0019872 - gene - - - "299.1, anon-96Ab, l(3)96Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264268 CR43768 - http://flybase.org/reports/FBgn0264268 non_protein_coding_gene - - - CR43768 - CR43768 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265529 CR44379 - http://flybase.org/reports/FBgn0265529 non_protein_coding_gene - - - "CR44379, lincRNA.327" - CR44379 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037632 CCT7 Chaperonin containing TCP1 subunit 7 http://flybase.org/reports/FBgn0037632 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012720 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000143937 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG8351, tcp-1eta, tcp1eta, Tcp-1-eta1, Tcp-1eta, Cct7, Q9VHL2_DROME, TCP1eta, TCPeta, CCT7, TCP1-eta" "IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012720:T-complex protein 1, eta subunit, IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG8351 11-Aug-17 DroID_v2017_08 "Drer\tcp1, Drer\mkks, Drer\cct7, Drer\bbs10" "Scer\CCT7, Scer\TCP1" Cele\cct-7 Xtro\cct7 "Mmus\Cct7, Mmus\Tcp1, Mmus\Mkks, Mmus\Bbs10" "Hsap\MKKS, Hsap\BBS10, Hsap\TCP1, Hsap\CCT7" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0053505 U3-55K U3 small nuclear riboprotein factor 55K http://flybase.org/reports/FBgn0053505 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:16829 U3 snoRNA binding ; GO:0034511 | inferred from direct assay rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000458584 neurogenesis ; GO:0022008 | inferred from mutant phenotype box C/D snoRNP complex ; GO:0031428 | inferred from sequence or structural similarity with HGNC:16829 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000458584 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with HGNC:16829 "CG10220, U3-55K, CG33505" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG33505 11-Aug-17 DroID_v2017_08 Drer\rrp9 Scer\RRP9 "Cele\Y54E5B.2, Cele\T02H6.1" Xtro\rrp9 Mmus\Rrp9 Hsap\RRP9 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0000838 fs(1)M24 female sterile (1) M24 http://flybase.org/reports/FBgn0000838 - gene - - - fs(1)M24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0031434 insv insensitive http://flybase.org/reports/FBgn0031434 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24478 transcription corepressor activity ; GO:0003714 | inferred from physical interaction with Su(H) chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay "negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype inferred from genetic interaction with numb inferred from genetic interaction with N inferred from genetic interaction with Su(H) negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "CG3227, BcDNA:RE55538, insv, Insv" IPR018379:BEN domain CG3227 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "microchaeta,adult abdominal sensillum,tormogen cell,ectopic,trichogen cell,macrochaeta,supernumerary,wing margin" FBgn0010846 l(3)04696 lethal (3) 04696 http://flybase.org/reports/FBgn0010846 - gene - - - "4712, l(3)04696" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0285910 VhaAC39-1 Vacuolar H[+] ATPase AC39 subunit 1 http://flybase.org/reports/FBgn0285910 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD_LOCUS:VMA6; SGD:S000004439 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181" "compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype vacuolar acidification ; GO:0007035 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR016727 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181" "vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD_LOCUS:VMA6; SGD:S000004439 plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype" "cho, VhaAC39-1, CG2934, vhaAC39, anon-EST:GressD5, vhaAC39-1, VhaAC39, Vhaac39, ATP6V0D1, V0d" "IPR002843:ATPase, V0 complex, c/d subunit, IPR016727:ATPase, V0 complex, subunit d" CG2934 11-Aug-17 DroID_v2017_08 Drer\atp6v0d1 Scer\VMA6 Cele\vha-16 "Xtro\atp6v0d1, Xtro\atp6v0d2" "Mmus\Atp6v0d2, Mmus\Atp6v0d1" "Hsap\ATP6V0D2, Hsap\ATP6V0D1" "eye color defective,viable,fertile" "pigment cell,Malpighian tubule" FBgn0259972 Sfp77F Seminal fluid protein 77F http://flybase.org/reports/FBgn0259972 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp77F, CG42482" - CG42482 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0285917 sbb scribbler http://flybase.org/reports/FBgn0285917 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription corepressor activity ; GO:0003714 | inferred from direct assay "copulation ; GO:0007620 | non-traceable author statement axon target recognition ; GO:0007412 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | traceable author statement regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "sbb, plt, mtv, bks, GM04742, CG5580, Bks, Group IIa, l(2)04440, disc6, sbb/mtv, Brakeless, Sbb" "IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG5580 11-Aug-17 DroID_v2017_08 "Drer\znf608, Drer\LOC796180, Drer\znf609a, Drer\znf609" - - Xtro\znf608 "Mmus\Zfp609, Mmus\Zfp608" "Hsap\ZNF608, Hsap\ZNF609" FBgn0265535 CG44385 - http://flybase.org/reports/FBgn0265535 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44385 - CG44385 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022255 l(2)k01103 lethal (2) k01103 http://flybase.org/reports/FBgn0022255 - gene - - - l(2)k01103 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051409 CG31409 - http://flybase.org/reports/FBgn0051409 protein_coding_gene - - - CG31409 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035737 Cpr65Ec Cuticular protein 65Ec http://flybase.org/reports/FBgn0035737 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr65Ec, CG8634, DmelCpr65Ec" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8634 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0014119 anon-96Fd anon-96Fd http://flybase.org/reports/FBgn0014119 - gene - - - anon-96Fd - - 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage , adult stage " " eye-antennal disc

, adult head

" FBgn0264436 CR43854 - http://flybase.org/reports/FBgn0264436 non_protein_coding_gene - - - CR43854 - CR43854 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002160 l(2)Sp1 lethal (2) Sp1 http://flybase.org/reports/FBgn0002160 - gene - - - l(2)Sp1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265075 CR44186 - http://flybase.org/reports/FBgn0265075 non_protein_coding_gene - - - CR44186 - CR44186 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010458 l(2)00231 lethal (2) 00231 http://flybase.org/reports/FBgn0010458 - gene - - - l(2)00231 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266408 CR45048 - http://flybase.org/reports/FBgn0266408 non_protein_coding_gene - - - CR45048 - CR45048 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058219 CG40219 - http://flybase.org/reports/FBgn0058219 protein_coding_gene - - - CG40219 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060710 l(3)S070209b lethal (3) S070209b http://flybase.org/reports/FBgn0060710 gene - - - "0702/09, l(3)S070209b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028101 l(3)S072613a lethal (3) S072613a http://flybase.org/reports/FBgn0028101 gene - - - "l(3)S072613, 0726/13, l(3)S072613a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0003330 Sce Sex combs extra http://flybase.org/reports/FBgn0003330 FBgn0020911 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with HGNC:10061 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24434 zinc ion binding ; GO:0008270 | inferred from sequence model chromatin silencing ; GO:0006342 | inferred from direct assay ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype histone H2A monoubiquitination ; GO:0035518 | inferred from mutant phenotype sex comb development ; GO:0045498 | inferred from direct assay multicellular organism development ; GO:0007275 | inferred from direct assay ventral cord development ; GO:0007419 | inferred from mutant phenotype "condensed chromosome, centromeric region ; GO:0000779 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay PRC1 complex ; GO:0035102 | inferred from direct assay PRC1 complex ; GO:0035102 | traceable author statement PcG protein complex ; GO:0031519 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay" "dRING1, dRing, RING1, dRING, DRING, Ring, Rnf2, Dring, Ding, CG5595, Sce, SCE, RING, Ring/Sce, dring, dRing1, Sce/dRing, sce, RING/Sce" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR032443:RAWUL domain" CG5595 11-Aug-17 DroID_v2017_08 "Drer\rnf2, Drer\lnx2b, Drer\lnx1" - "Cele\B0432.13, Cele\spat-3" "Xtro\rnf2, Xtro\traip, Xtro\ring1" "Mmus\Pcgf3, Mmus\Brca1, Mmus\Traip, Mmus\Rnf2, Mmus\Ring1" "Hsap\RNF2, Hsap\RING1, Hsap\PCGF3, Hsap\BRCA1" "lethal - all die before end of pupal stage,some die during pupal stage,suppressor of variegation,dominant,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,decreased cell number,somatic clone,mitotic cell cycle defective,tumorigenic,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die" "adult thorax,Fell hairs,ectopic,abdominal 4 ventral denticle belt,denticle belt,embryonic abdominal segment,rescuable maternal effect,embryonic abdominal segment 8,embryonic head,stage 14 embryo,embryonic thoracic segment,larval abdominal segment 7,larval abdominal segment 1,germline clone,larval abdominal segment 2,larval abdominal segment 3,larval abdominal segment 4,larval abdominal segment 5,larval abdominal segment 6,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,Keilin's organ,Kolbchen,egg chamber,somatic clone,germarium region 3,interfollicle cell,cell non-autonomous,neuroblast,embryonic/larval tracheal system,eye disc,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,prothoracic ventral denticle belt,wing,mesothoracic tergum" FBgn0024968 FebpN ftz enhancer binding protein N http://flybase.org/reports/FBgn0024968 - gene DNA binding ; GO:0003677 | inferred from direct assay biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from direct assay FebpN - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020871 anon-Q177 anon-Q177 http://flybase.org/reports/FBgn0020871 - gene - - - "2-Q177, anon-Q177" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0032031 CG13390 - http://flybase.org/reports/FBgn0032031 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006073, InterPro:IPR006169, InterPro:IPR014100, InterPro:IPR031167 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR014100 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR014100" - - CG13390 "IPR005225:Small GTP-binding protein domain, IPR006073:GTP binding domain, IPR006169:GTP1/OBG domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014100:GTP-binding protein Obg/CgtA, IPR031167:OBG-type guanine nucleotide-binding (G) domain" CG13390 11-Aug-17 DroID_v2017_08 "Drer\gtpbp10, Drer\mtg2" "Scer\MTG2, Scer\MSS1" "Cele\C26E6.12, Cele\M01E5.2" "Xtro\gtpbp10, Xtro\mtg2" "Mmus\Gtpbp10, Mmus\Mtg2" "Hsap\GTPBP10, Hsap\MTG2" viable FBgn0086075 snoRNA:Me28S-G3253 - http://flybase.org/reports/FBgn0086075 snoRNA_gene - - - "snoRNA:28S-G3253, 28S-Gm3253, CR34704, snoRNA:Me28S-G3253, Me28S-G3253" - CR34704 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262396 mir-314 mir-314 stem loop http://flybase.org/reports/FBgn0262396 miRNA_gene - - - "dme-mir-314, mir-314, miR-314, CR42933, CR33618, dme-miR-314-5p" - CR42933 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039003 wfs1 wolfram syndrome 1 http://flybase.org/reports/FBgn0039003 protein_coding_gene - - - "CG4917, wfs1" IPR026209:Wolframin family CG4917 11-Aug-17 DroID_v2017_08 "Drer\wfs1a, Drer\wfs1b" - - Xtro\wfs1 Mmus\Wfs1 Hsap\WFS1 "viable,fertile" DRSC15676 K -0.271374309 0.719126685 -0.050197093 0.042517314 2.625593023 0.835816879 FBgn0036608 CG13040 - http://flybase.org/reports/FBgn0036608 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13040 IPR007614:Retinin-like protein CG13040 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0062528 l(3)88EFd lethal (3) 88EFd http://flybase.org/reports/FBgn0062528 gene - - - l(3)88EFd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000587 E(S) Enhancer of Star http://flybase.org/reports/FBgn0000587 - gene - - - E(S) - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" eye FBgn0259286 C575 - http://flybase.org/reports/FBgn0259286 gene - - - C575 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0053222 CR33222 - http://flybase.org/reports/FBgn0053222 pseudogene_attribute - - - "CG33222, CR11386, CR33222" - CR33222 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039925 Kif3C Kinesin family member 3C http://flybase.org/reports/FBgn0039925 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | non-traceable author statement microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 "CG17461, DmKIF3C, KIF3C, CG17459, Kif3C, Kif3c, KIF3Cdm, DmKif3C, KIF 3C, CP38609, KIF 24, KIF17" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019821:Kinesin motor domain, conserved site" CG17461 11-Aug-17 DroID_v2017_08 "Drer\LOC100333558, Drer\kif3b, Drer\kif17, Drer\kif26aa, Drer\LOC100331925, Drer\si:dkey-86l18.8, Drer\kif3cb, Drer\kif26bb, Drer\kif26ba, Drer\kifc1, Drer\kif3a, Drer\kif15" "Scer\CIN8, Scer\KAR3, Scer\KIP1" "Cele\klp-11, Cele\osm-3, Cele\klp-20" "Xtro\kif3a, Xtro\kif3b, Xtro\kif9, Xtro\kif3c, Xtro\kif26a, Xtro\kif15" "Mmus\Kif9, Mmus\Kif3c, Mmus\Kif26b, Mmus\Kifc1, Mmus\Gm1305, Mmus\Kif26a, Mmus\Kifc5b, Mmus\Kif6, Mmus\Kif12, Mmus\Kif3b, Mmus\Kif17, Mmus\Kif15, Mmus\Kif3a" "Hsap\KIF17, Hsap\KIFC1, Hsap\KIF26A, Hsap\KIF15, Hsap\KIF3C, Hsap\KIF9, Hsap\KIF26B, Hsap\KIF3A, Hsap\KIF3B, Hsap\KIF6, Hsap\KIF12" viable FBgn0001230 Hsp68 Heat shock protein 68 http://flybase.org/reports/FBgn0001230 - protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P38646 neurogenesis ; GO:0022008 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P38646 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P38646 lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "hsp68, Hsp-68, HSP68, 68, CG5436, Hsp68, HSP68_DROME, DmHsp68" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG5436 11-Aug-17 DroID_v2017_08 "Drer\hspa13, Drer\hspa5, Drer\hsp70.2, Drer\si:dkey-4p15.3, Drer\hsp70.1, Drer\hspa12b, Drer\hspa14, Drer\hspa8, Drer\hsc70, Drer\si:ch211-199o1.2, Drer\nckap1, Drer\hspa12a, Drer\hsp70l" "Scer\SSA1, Scer\SSB2, Scer\SSA4, Scer\SSA2, Scer\SSA3, Scer\KAR2, Scer\SSQ1, Scer\SSB1, Scer\SSZ1" "Cele\F11F1.1, Cele\hsp-4, Cele\hsp-3, Cele\F44E5.4, Cele\gex-3, Cele\hsp-70, Cele\F44E5.5, Cele\hsp-1" "Xtro\hspa1l, Xtro\hspa2, Xtro\hsp70, Xtro\hspa8, Xtro\hspa5, Xtro\hspa1b, Xtro\hspa14, Xtro\nckap1, Xtro\hspa1a, Xtro\hspa13, Xtro\hspa12b, Xtro\nckap1l" "Mmus\Hspa1b, Mmus\Hspa14, Mmus\Hspa12b, Mmus\Hspa1a, Mmus\Hspa2, Mmus\Hspa13, Mmus\Hspa1l, Mmus\Hspa12a, Mmus\Nckap1l, Mmus\Hspa8, Mmus\Hspa5, Mmus\Nckap1" "Hsap\HSPA8, Hsap\HSPA5, Hsap\HSPA12B, Hsap\HSPA6, Hsap\NCKAP1L, Hsap\NCKAP1, Hsap\HSPA12A, Hsap\HSPA1L, Hsap\HSPA13, Hsap\HSPA1B, Hsap\HSPA1A, Hsap\HSPA2, Hsap\HSPA14" "chemical resistant,long lived,starvation stress response defective,body color defective,partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective" "mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell" FBgn0067748 l(1)G0210 lethal (1) G0210 http://flybase.org/reports/FBgn0067748 gene - - - l(1)G0210 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0002953 nofG no object fixation G http://flybase.org/reports/FBgn0002953 - gene - - - nofG - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective eye FBgn0038429 CG14882 - http://flybase.org/reports/FBgn0038429 protein_coding_gene [methionine synthase] reductase activity ; GO:0030586 | inferred from sequence or structural similarity with HGNC:7473 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR003097, InterPro:IPR017927, InterPro:IPR017938, InterPro:IPR023173 methionine biosynthetic process ; GO:0009086 | inferred from sequence or structural similarity with HGNC:7473" - "BcDNA:SD10961, CG14882" "IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR001709:Flavoprotein pyridine nucleotide cytochrome reductase, IPR003097:FAD-binding, type 1, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel" CG14882 11-Aug-17 DroID_v2017_08 "Drer\mtrr, Drer\porb, Drer\nos2b, Drer\nos1, Drer\pora, Drer\nos2a" "Scer\NCP1, Scer\MET10" Cele\mtrr-1 "Xtro\nos1, Xtro\por, Xtro\mtrr, Xtro\nos2, Xtro\nos3" "Mmus\Nos2, Mmus\Por, Mmus\Mtrr, Mmus\Nos1, Mmus\Nos3" "Hsap\NOS2, Hsap\NOS1, Hsap\POR, Hsap\NOS3, Hsap\MTRR" viable FBgn0038029 GstD11 Glutathione S transferase D11 http://flybase.org/reports/FBgn0038029 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "BcDNA:RE72392, cg17639, CG17639, DmGSTD11, GstD11, gstd11, GSTD11" "IPR004045:Glutathione S-transferase, N-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17639 11-Aug-17 DroID_v2017_08 "Drer\gstt1a, Drer\vars, Drer\gstr, Drer\eef1g, Drer\eef1e1, Drer\gstt2, Drer\mars, Drer\gstt1b" "Scer\GTT1, Scer\CAM1, Scer\TEF4, Scer\GTT2, Scer\YGR201C, Scer\URE2" Cele\gst-34 "Xtro\eef1e1, Xtro\eef1g, Xtro\gstt1" "Mmus\Gstt4, Mmus\Vars, Mmus\Eef1e1, Mmus\Mars, Mmus\Gstt1, Mmus\Gstt2, Mmus\Eef1g, Mmus\Gstt3" "Hsap\EEF1E1, Hsap\GSTT1, Hsap\MARS, Hsap\GSTT2, Hsap\VARS, Hsap\EEF1G, Hsap\GSTT2B" "viable,fertile" FBgn0260255 GSd226 - http://flybase.org/reports/FBgn0260255 gene - - - GSd226 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0039103 CG13819 - http://flybase.org/reports/FBgn0039103 protein_coding_gene - - - CG13819 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC14669 I -0.169621679 4.818628291 0.59764478 0.699219966 0.125739588 -0.867770565 FBgn0267351 Topors Topoisomerase I-interacting protein http://flybase.org/reports/FBgn0267351 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 DNA binding ; GO:0003677 | contributes_to inferred from direct assay lamin binding ; GO:0005521 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P08970 inferred from physical interaction with UniProtKB:Q86B87 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P14003 "protein polyubiquitination ; GO:0000209 | inferred from direct assay centrosome separation ; GO:0051299 | inferred from mutant phenotype meiotic chromosome condensation ; GO:0010032 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from direct assay male meiosis ; GO:0007140 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from direct assay male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from genetic interaction with UniProtKB:P14003 nuclear membrane organization ; GO:0071763 | inferred from mutant phenotype nucleus organization ; GO:0006997 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay "CG15104, Topors, dtopors, nbl, dTopors, TOPORS" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR018957:Zinc finger, C3HC4 RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG15104 11-Aug-17 DroID_v2017_08 "Drer\toporsa, Drer\toporsb" - "Cele\C32D5.11, Cele\C32D5.10" Xtro\topors "Mmus\Toporsl, Mmus\Topors" Hsap\TOPORS DRSC06531 I -0.762372109 1.654920577 0.585662723 -1.185527546 0.456563597 0.994001174 FBgn0015760 Map85 Microtubule-associated protein 85 http://flybase.org/reports/FBgn0015760 - gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay "DMAP-85, Map85" - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage&& larval stage&& adult stage " embryonic stage | early , embryonic stage | 10-15hr , larval stage , embryonic stage | late , embryonic stage | 5hr , embryonic stage | mid , embryonic stage | 1-4hr , embryonic stage | 6-9hr " " longitudinal connective

, embryonic central nervous system

, connective

, amnioserosa

" FBgn0005182 l(2)S4 lethal of Seto 4 http://flybase.org/reports/FBgn0005182 - gene - - - l(2)S4 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "puparium,epidermis" FBgn0085825 CR41619 - http://flybase.org/reports/FBgn0085825 rRNA_gene - - - CR41619 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024725 Su(var)28D Su(var)28D http://flybase.org/reports/FBgn0024725 - gene - - - Su(var)28D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005469 l(1)ts340 lethal (1) ts340 http://flybase.org/reports/FBgn0005469 FBgn0001830 gene - - - l(1)ts340 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0034885 Eglp4 Entomoglyceroporin 4 http://flybase.org/reports/FBgn0034885 protein_coding_gene channel activity ; GO:0015267 | inferred from sequence or structural similarity with Drip water channel activity ; GO:0015250 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 transmembrane transport ; GO:0055085 | inferred from sequence or structural similarity with Drip renal system process ; GO:0003014 | inferred from expression pattern ion transmembrane transport ; GO:0034220 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Drip integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 "CG4019, Aqp4019, Eglp4, Eglp 4" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR022357:Major intrinsic protein, conserved site, IPR023271:Aquaporin-like" CG4019 11-Aug-17 DroID_v2017_08 "Drer\aqp1a.2, Drer\aqp9b, Drer\aqp3a, Drer\aqp8b, Drer\aqp8a.1, Drer\mipb, Drer\mipa, Drer\aqp7, Drer\aqp10a, Drer\aqp8a.2, Drer\aqp1a.1, Drer\aqp4" "Scer\AQY1, Scer\AQY2, Scer\FPS1, Scer\YLL053C, Scer\YFL054C" "Cele\aqp-6, Cele\aqp-5, Cele\aqp-8, Cele\aqp-4, Cele\aqp-7, Cele\aqp-2, Cele\aqp-3" "Xtro\mip, Xtro\LOC100216133, Xtro\aqp5, Xtro\aqp2" "Mmus\Aqp7, Mmus\Aqp8, Mmus\Aqp4, Mmus\Aqp6, Mmus\Aqp3, Mmus\Aqp9, Mmus\Mip, Mmus\Aqp2, Mmus\Aqp5, Mmus\Aqp1" "Hsap\AQP4, Hsap\AQP5, Hsap\AQP9, Hsap\AQP2, Hsap\MIP, Hsap\AQP8, Hsap\AQP10, Hsap\AQP3, Hsap\AQP1, Hsap\AQP6, Hsap\AQP7" "viable,lethal" FBgn0051198 CG31198 - http://flybase.org/reports/FBgn0051198 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "CG5845, anon-WO0140519.12, anon-WO0140519.24, CG31198" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG31198 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-198g19.1, Drer\si:ch211-276a23.5, Drer\ctrl, Drer\enpep, Drer\si:ch211-106j24.1, Drer\erap2, Drer\anpepb, Drer\erap1b, Drer\si:ch211-149p5.1, Drer\anpepa, Drer\lnpep, Drer\npepps, Drer\erap1a" "Scer\APE2, Scer\AAP1, Scer\TMA108" "Cele\mnp-1, Cele\T12E12.6, Cele\R03G8.6, Cele\AC3.5, Cele\Y67D8C.9, Cele\VB0395L.1, Cele\Y53F4B.20, Cele\Y42A5A.1, Cele\F49B2.6, Cele\T16G12.1, Cele\pam-1, Cele\T07F10.1, Cele\R03G8.4" "Xtro\erap1, Xtro\npepps, Xtro\lvrn, Xtro\anpep, Xtro\enpep, Xtro\lnpep" "Mmus\Erap1, Mmus\Enpep, Mmus\Lvrn, Mmus\Anpep, Mmus\Lnpep, Mmus\Npepps, Mmus\Trhde, Mmus\Rnpep" "Hsap\TRHDE, Hsap\LVRN, Hsap\ENPEP, Hsap\ANPEP, Hsap\NPEPPS, Hsap\RNPEP, Hsap\ERAP2, Hsap\ERAP1, Hsap\LNPEP" viable FBgn0036622 CG4753 - http://flybase.org/reports/FBgn0036622 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR002123" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002123 - "CG4753, AGPAT4" "IPR002123:Phospholipid/glycerol acyltransferase, IPR032098:Acyltransferase, C-terminal domain" CG4753 11-Aug-17 DroID_v2017_08 "Drer\agpat3, Drer\lpgat1, Drer\agpat5, Drer\lclat1, Drer\agpat4" "Scer\YDR018C, Scer\CST26" "Cele\acl-11, Cele\acl-8, Cele\acl-9, Cele\bus-18" "Xtro\lclat1, Xtro\lpgat1, Xtro\agpat5, Xtro\agpat3, Xtro\agpat4" "Mmus\Lpgat1, Mmus\Agpat5, Mmus\Agpat3, Mmus\Lclat1, Mmus\Agpat4" "Hsap\LCLAT1, Hsap\LPGAT1, Hsap\AGPAT3, Hsap\AGPAT4, Hsap\AGPAT5" "viable,fertile" FBgn0028981 tRNA:Ser-CGA-1-4 transfer RNA:Serine-CGA 1-4 http://flybase.org/reports/FBgn0028981 tRNA_gene triplet codon-amino acid adaptor activity ; GO:0030533 | non-traceable author statement UCG codon-amino acid adaptor activity ; GO:0033408 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033408 cytosol ; GO:0005829 | inferred by curator from GO:0033408 "CR30224, tRNA(4Ser), EST E, 444-3, tRNA[Ser][[4]], tRNA[Ser], Ser tRNA[Ser], AE002787.trna50-SerCGA, tRNA:S:CGA:AE002787, tRNA:ser, tRNA:S, tRNA:ser4, tRNA:S4, tRNA:S4:64D, tRNA:ser4:64D, tRNA[[Ser]], chr2R.trna33-SerCGA, tRNA-Ser-CGA-1-4, tRNA:Ser-CGA-1-4, tRNA:S4:56D, UCG" - CR30224 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069065 5SrRNA-Psi 5S ribosomal RNA pseudogene http://flybase.org/reports/FBgn0069065 pseudogene_attribute - - - 5SrRNA-Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267280 CR45716 - http://flybase.org/reports/FBgn0267280 pseudogene_attribute - - - CR45716 - CR45716 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011769 Fdx1 Ferredoxin 1 http://flybase.org/reports/FBgn0011769 FBgn0062914 protein_coding_gene "electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with HGNC:3638 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from sequence or structural similarity with HGNC:3638" pupariation ; GO:0035073 | inferred from mutant phenotype positive regulation of ecdysteroid biosynthetic process ; GO:0045998 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:3638 "CG4205, BcDNA:RH67819, Fdx1, Fdxh" "IPR018298:Adrenodoxin, iron-sulphur binding site, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR001055:Adrenodoxin, IPR012675:Beta-grasp domain" CG4205 11-Aug-17 DroID_v2017_08 "Drer\fdx1b, Drer\fdx1l, Drer\fdx1, Drer\cox15" "Scer\COX15, Scer\YAH1" "Cele\Y73F8A.27, Cele\cox-15" "Xtro\fdx1l, Xtro\fdx1" "Mmus\Fdx1l, Mmus\Fdx1, Mmus\Cox15" "Hsap\FDX1, Hsap\FDX1L, Hsap\COX15" viable FBgn0052647 CG32647 - http://flybase.org/reports/FBgn0052647 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT35953, CG15723, CG3794, CG18453, BcDNA:RH40632, CG32647" - CG32647 11-Aug-17 DroID_v2017_08 Drer\dgcr2 - - Xtro\dgcr2 Mmus\Dgcr2 Hsap\DGCR2 "viable,fertile" FBgn0060674 l(3)S077515 lethal (3) S077515 http://flybase.org/reports/FBgn0060674 gene - - - "0775/15, l(3)S077515" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0085413 CG34384 - http://flybase.org/reports/FBgn0085413 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 diacylglycerol kinase activity ; GO:0004143 | inferred from sequence or structural similarity with HGNC:2854 diacylglycerol kinase activity ; GO:0004143 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 diacylglycerol kinase activity ; GO:0004143 | non-traceable author statement metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017438 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 protein oligomerization ; GO:0051259 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 phosphorylation ; GO:0016310 | non-traceable author statement protein kinase C-activating G-protein coupled receptor signaling pathway ; GO:0007205 | inferred from sequence or structural similarity with HGNC:2854 protein kinase C-activating G-protein coupled receptor signaling pathway ; GO:0007205 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 endosome ; GO:0005768 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 "CG34384, CG14462, DGKd, CG9851, CG2667, CG31187, dgkd" "IPR000756:Diacylglycerol kinase, accessory domain, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR001206:Diacylglycerol kinase, catalytic domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR013761:Sterile alpha motif/pointed domain, IPR001660:Sterile alpha motif domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG34384 11-Aug-17 DroID_v2017_08 "Drer\dgkh, Drer\si:dkey-172j4.3" - Cele\dgk-4 Xtro\dgkh "Mmus\Dgkd, Mmus\Dgkh, Mmus\Dgkk" "Hsap\DGKD, Hsap\DGKH, Hsap\DGKK" FBgn0032442 CG15485 - http://flybase.org/reports/FBgn0032442 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG15485 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG15485 11-Aug-17 DroID_v2017_08 "Drer\ece2b, Drer\phex, Drer\mmel1, Drer\ece1" - "Cele\nep-26, Cele\nep-12, Cele\nep-17, Cele\nep-18, Cele\nep-6, Cele\nep-16, Cele\nep-10, Cele\nep-5" "Xtro\ece2, Xtro\ece1, Xtro\ecel1, Xtro\mmel1" "Mmus\Mmel1, Mmus\Mme, Mmus\Ece2, Mmus\Phex, Mmus\Kel, Mmus\Ecel1, Mmus\Ece1" "Hsap\ECE1, Hsap\ECEL1, Hsap\KEL, Hsap\PHEX, Hsap\MMEL1, Hsap\MME, Hsap\ECE2" viable FBgn0037225 TwdlG TweedleG http://flybase.org/reports/FBgn0037225 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlG, CG14643" IPR004145:Domain of unknown function DUF243 CG14643 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020371 Tim17b2 Translocase inner membrane 17 http://flybase.org/reports/FBgn0020371 "FBgn0032565, FBgn0065011, FBgn0065023" protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000050380 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O60830 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O60830 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:O60830 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity "BG:DS01845.2, dmTim17, BcDNA:AT13511, BcDNA:AT05822, Tim17, CG15257, Tim17b2" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG15257 11-Aug-17 DroID_v2017_08 "Drer\timm17a, Drer\timm17b" Scer\TIM17 "Cele\D2096.1, Cele\E04A4.5" Xtro\timm17a "Mmus\Timm17a, Mmus\Timm17b" "Hsap\TIMM17B, Hsap\TIMM17A" viable FBgn0261873 sdt stardust http://flybase.org/reports/FBgn0261873 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with par-6 guanylate kinase activity ; GO:0004385 | inferred from sequence or structural similarity with MGI:MGI:1927339 establishment of epithelial cell polarity ; GO:0090162 | inferred from electronic annotation with InterPro:IPR031185 bicellular tight junction assembly ; GO:0070830 | inferred from electronic annotation with InterPro:IPR031185 establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from expression pattern inferred from mutant phenotype inferred from physical interaction with crb zonula adherens assembly ; GO:0045186 | traceable author statement apical protein localization ; GO:0045176 | inferred from mutant phenotype zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | non-traceable author statement morphogenesis of a polarized epithelium ; GO:0001738 | traceable author statement cell-cell junction assembly ; GO:0007043 | non-traceable author statement establishment or maintenance of polarity of embryonic epithelium ; GO:0016332 | inferred from mutant phenotype photoreceptor cell development ; GO:0042461 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype establishment or maintenance of neuroblast polarity ; GO:0045196 | NOT inferred from expression pattern inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype establishment or maintenance of neuroblast polarity ; GO:0045196 | NOT inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement apical plasma membrane ; GO:0016324 | non-traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay subapical complex ; GO:0035003 | traceable author statement septate junction ; GO:0005918 | traceable author statement subapical complex ; GO:0035003 | inferred from physical interaction with Patj apical plasma membrane ; GO:0016324 | traceable author statement apicolateral plasma membrane ; GO:0016327 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG32717, Sdt, sdt, CG12657, PALS1, Std, CG15341, CG15339, std, anon-EST:fe2E6, l(1)7Ef, CG1617, CG15340, CG12658, CG15342, pal1, Pals1, BP1063, cMAGUK1, cGUK1" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR014775:L27 domain, C-terminal, IPR011511:Variant SH3 domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR008144:Guanylate kinase-like domain, IPR004172:L27 domain, IPR001478:PDZ domain, IPR001452:SH3 domain, IPR020590:Guanylate kinase, conserved site, IPR031185:MAGUK p55 subfamily member 5" CG32717 11-Aug-17 DroID_v2017_08 "Drer\mpp1, Drer\mpp5b, Drer\mpp2a, Drer\mpp5a, Drer\mpp6b, Drer\mpp7a, Drer\mpp3a, Drer\mpp6a, Drer\caska, Drer\mpp4a, Drer\mpp2b, Drer\mpp7b, Drer\mpp3b, Drer\si:ch73-272h16.4, Drer\LOC556594" - "Cele\magu-2, Cele\magu-1, Cele\lin-2" "Xtro\mpp6, Xtro\mpp2, Xtro\mpp7, Xtro\mpp1, Xtro\mpp5, Xtro\cask" "Mmus\Mpp5, Mmus\Cask, Mmus\Mpp7, Mmus\Mpp1, Mmus\Mpp3, Mmus\Mpp4, Mmus\Mpp2, Mmus\Mpp6" "Hsap\MPP1, Hsap\MPP3, Hsap\MPP4, Hsap\MPP2, Hsap\CASK, Hsap\MPP6, Hsap\MPP7, Hsap\MPP5" pupal stage photoreceptor cell stalk | apical

FBgn0000420 dbl dichaete beadex lethal http://flybase.org/reports/FBgn0000420 - gene - - - dbl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,cold sensitive" wing FBgn0051529 CG31529 - http://flybase.org/reports/FBgn0051529 protein_coding_gene - - - "BcDNA:LD01463, CG31529" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030250 CG15206 - http://flybase.org/reports/FBgn0030250 protein_coding_gene - - - CG15206 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028519 hll heimdall http://flybase.org/reports/FBgn0028519 protein_coding_gene long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from direct assay long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from sequence or structural similarity long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from sequence or structural similarity with UniProtKB:Q9V3S9 mesoderm development ; GO:0007498 | inferred from expression pattern long-chain fatty acid metabolic process ; GO:0001676 | inferred from sequence or structural similarity with UniProtKB:Q9V3S9 fatty acid metabolic process ; GO:0006631 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype - "2a9, BG:DS05899.1, I, anon-EST:CL2a9, CG4500, hll, dbb" IPR000873:AMP-dependent synthetase/ligase CG4500 11-Aug-17 DroID_v2017_08 "Drer\acsl2, Drer\acsl1b, Drer\acsl4a, Drer\acsl1a, Drer\acsl5, Drer\acsl4b, Drer\acsbg2, Drer\acsl3b, Drer\acsbg1, Drer\acsl6" "Scer\FAA1, Scer\FAA4, Scer\FAA3, Scer\FAA2" Cele\acs-5 "Xtro\acsl6, Xtro\acsl4, Xtro\acsbg2, Xtro\acsl5, Xtro\acsbg1, Xtro\acsl1" "Mmus\Acsl3, Mmus\Acsl6, Mmus\1700061G19Rik, Mmus\Acsbg2, Mmus\Acsl1, Mmus\Acsl4, Mmus\Acsl5, Mmus\Acsbg1" "Hsap\ACSL4, Hsap\ACSBG2, Hsap\ACSL6, Hsap\ACSL3, Hsap\ACSBG1, Hsap\ACSL1, Hsap\ACSL5" " embryonic stage | stage 5 , embryonic stage | stage 17 , embryonic stage , embryonic stage | stage >5 " " mesoderm anlage

, embryonic/larval fat body

, ventral furrow

, yolk

, mesoderm

" viable FBgn0061037 l(3)S023844b lethal (3) S023844b http://flybase.org/reports/FBgn0061037 gene - - - "0238/44, l(3)S023844b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040007 RpL38 Ribosomal protein L38 http://flybase.org/reports/FBgn0040007 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002675 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "CG18001, E-2b, l(2)41Af, M(2)41A, 41Ag, 41Af, CG40278, l(2)EMS45-72, GroupIV, l(2R)A', M(2)S2, l(2)41Ag, M(2)S3, l(2)EMS4-72, l(2)41Ai, BcDNA:RE42506, RpL38, Rp L38" IPR002675:Ribosomal protein L38e CG18001 11-Aug-17 DroID_v2017_08 "Drer\rpl38, Drer\nr2c2ap" Scer\RPL38 Cele\rpl-38 "Xtro\nr2c2ap, Xtro\rpl38" "Mmus\Nr2c2ap, Mmus\Rpl38" "Hsap\RPL38, Hsap\NR2C2AP" "lethal,developmental rate defective,Minute,dominant,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,increased cell size,decreased cell number,recessive" "prothoracic gland,chaeta,wing vein,ectopic,wing,wing hair,wing margin" DRSC07818 IE -2.199442934 -1.515981937 -0.263835024 -4.066607364 0.843777269 1.449596649 FBgn0053679 CG33679 - http://flybase.org/reports/FBgn0053679 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1003, CG33679" IPR010512:Protein of unknown function DUF1091 CG33679 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0065894 l(2)SH0213 lethal (2) SH0213 http://flybase.org/reports/FBgn0065894 gene - - - "l(2)SH0213, l(2)SH2 0213" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035186 CG13912 - http://flybase.org/reports/FBgn0035186 protein_coding_gene - - - CG13912 - CG13912 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053480 CG33480 - http://flybase.org/reports/FBgn0053480 protein_coding_gene - - - CG33480 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033304 Cyp6a13 Cyp6a13 http://flybase.org/reports/FBgn0033304 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype" - "CG2397, cyp6a13, Cyp6a13, 6a13" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG2397 11-Aug-17 DroID_v2017_08 "Drer\tbxas1, Drer\cyp51, Drer\cyp3c2, Drer\cyp3c1, Drer\cyp3c3, Drer\cyp3c4, Drer\cyp3a65" Scer\ERG11 "Cele\cyp-25A6, Cele\cyp-25A4, Cele\cyp-13A12, Cele\cyp-13B1, Cele\cyp-25A2, Cele\cyp-44A1, Cele\cyp-13A6, Cele\cyp-35B1, Cele\cyp-13A2, Cele\cyp-13A1, Cele\cyp-25A3, Cele\cyp-13A10, Cele\cyp-13B2, Cele\cyp-25A1, Cele\cyp-13A8, Cele\cyp-13A4, Cele\cyp-13A11, Cele\cyp-13A7, Cele\cyp-13A5, Cele\cyp-43A1, Cele\cyp-13A3" "Xtro\LOC100494419, Xtro\cyp3a5, Xtro\tbxas1, Xtro\cyp3a4" "Mmus\Cyp3a13, Mmus\Cyp3a16, Mmus\Cyp3a41a, Mmus\Cyp3a25, Mmus\Cyp3a57, Mmus\Cyp3a59, Mmus\Cyp3a44, Mmus\Cyp3a11, Mmus\Cyp3a41b, Mmus\Cyp51, Mmus\Tbxas1" "Hsap\CYP3A7-CYP3A51P, Hsap\TBXAS1, Hsap\CYP3A43, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\CYP3A4" "viable,fertile" FBgn0051708 DIP-zeta Dpr-interacting protein zeta http://flybase.org/reports/FBgn0051708 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CT32338, CT32337, CG13105, CG13104, CG13103, CG31708, DIP-zeta, 31708" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG31708 11-Aug-17 DroID_v2017_08 "Drer\kirrelb, Drer\f11r.2, Drer\LOC100151468, Drer\mxra8a, Drer\esamb, Drer\dscama, Drer\vsig8a, Drer\cd4-2, Drer\ncam1b, Drer\cd4-1, Drer\jam3a, Drer\negr1, Drer\jam3b, Drer\si:ch1073-459j12.1, Drer\si:ch211-215e19.3, Drer\itgb4, Drer\kirrel3a, Drer\igsf9a, Drer\lrit3b, Drer\f11r.1, Drer\si:dkey-250k15.10, Drer\zgc:110372, Drer\lrit1b, Drer\jam2b, Drer\ush2a, Drer\jam2a, Drer\esama, Drer\cxadr, Drer\pigrl4.2, Drer\kirrel3l, Drer\lrit1a, Drer\lrit3a, Drer\zgc:153073, Drer\gpa33, Drer\si:ch211-9d9.7, Drer\paplna, Drer\ntm, Drer\kirrela, Drer\sdk1b, Drer\sdk1a, Drer\cxcr3.1, Drer\si:dkey-65b12.12, Drer\kirrel3b, Drer\vsig8b, Drer\opcml, Drer\igsf11, Drer\si:zfos-1011f11.1, Drer\igsf9bb, Drer\mxra8b" - "Cele\zig-1, Cele\zig-11, Cele\zig-7, Cele\rig-5" "Xtro\lsamp, Xtro\igsf9b, Xtro\lrit3, Xtro\ntm, Xtro\kirrel2, Xtro\papln, Xtro\negr1" "Mmus\Igsf5, Mmus\Lrit3, Mmus\Kirrel2, Mmus\Jam2, Mmus\F11r, Mmus\Lsamp, Mmus\Ntm, Mmus\Ptprq, Mmus\Jam3, Mmus\Vsig2, Mmus\Negr1, Mmus\Gpa33, Mmus\Vsir, Mmus\Gm1123, Mmus\Hepacam2, Mmus\Igsf11, Mmus\Vsig1, Mmus\Papln, Mmus\Clmp, Mmus\Kirrel, Mmus\Sdk1, Mmus\Esam, Mmus\Mxra8, Mmus\Vsig8, Mmus\Igsf9b, Mmus\Opcml, Mmus\Cxadr, Mmus\Iglon5, Mmus\Kirrel3, Mmus\Lrit1" "Hsap\VSIG2, Hsap\ESAM, Hsap\VSIG1, Hsap\KIRREL2, Hsap\CLMP, Hsap\CXADR, Hsap\PAPLN, Hsap\KIRREL3, Hsap\C1orf204, Hsap\KIRREL, Hsap\USH2A, Hsap\LRIT1, Hsap\IGLON5, Hsap\F11R, Hsap\JAM3, Hsap\VSIG8, Hsap\JAM2, Hsap\LRIT3, Hsap\SDK1, Hsap\IGSF5, Hsap\OPCML, Hsap\IGSF9B, Hsap\LSAMP, Hsap\IGSF11, Hsap\MXRA8, Hsap\C10orf54, Hsap\NEGR1, Hsap\GPA33, Hsap\NTM" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC02204 IE 1.129054264 -2.455230506 1.574180181 1.700076426 0.178792256 -0.648791747 FBgn0039311 CG10513 - http://flybase.org/reports/FBgn0039311 protein_coding_gene - - - "CT29500, CG10513" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG10513 11-Aug-17 DroID_v2017_08 - - "Cele\dhs-27, Cele\H06H21.8, Cele\F56A4.5, Cele\E02C12.10, Cele\E02C12.8, Cele\C18B10.6, Cele\F59B1.10, Cele\C29F7.2, Cele\Y45G12C.4, Cele\nhr-246, Cele\E02C12.9, Cele\F58B4.5, Cele\C29F7.1, Cele\H37A05.2, Cele\E02C12.6" - - - viable FBgn0003588 Su(var)2-8 Suppressor of variegation 2-8 http://flybase.org/reports/FBgn0003588 - gene - - - "Su-var(2)8, Su-var, Su2, Su(var)2-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0004164 fs(2)sun female sterile (2) supernova http://flybase.org/reports/FBgn0004164 - gene - - - "sun, fs(2)sun" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0015036 Cyp4ae1 Cytochrome P450-4ae1 http://flybase.org/reports/FBgn0015036 FBgn0014088 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "Cypae1, 4ae1, EG:152A3.6, CG10755, CYP4E4, P450, P-450, TcD20, I, anon-2Ea, Cyp4e4, Cyp4ae1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10755 11-Aug-17 DroID_v2017_08 "Drer\cyp19a1a, Drer\cyp46a1.2, Drer\cyp19a1b, Drer\cyp4t8, Drer\cyp46a1.1, Drer\cyp20a1, Drer\cyp3c1, Drer\cyp46a1.4, Drer\cyp46a1.3, Drer\cyp4f3, Drer\cyp3c4, Drer\LOC100329425, Drer\cyp4v8, Drer\cyp26b1, Drer\cyp3c3, Drer\cyp3c2, Drer\cyp26a1, Drer\cyp4v7, Drer\cyp3a65, Drer\cyp26c1" "Scer\DIT2, Scer\ERG5" "Cele\cyp-32B1, Cele\cyp-37B1, Cele\cyp-13A1, Cele\cyp-29A4, Cele\cyp-37A1, Cele\cyp-25A4, Cele\cyp-13A10, Cele\cyp-13A12, Cele\cyp-25A2, Cele\cyp-13A11, Cele\cyp-29A3, Cele\cyp-13A3, Cele\cyp-13A8, Cele\cyp-13A5, Cele\cyp-13A7, Cele\cyp-31A5, Cele\cyp-13A4, Cele\cyp-25A3, Cele\cyp-42A1, Cele\cyp-25A1, Cele\cyp-29A2, Cele\cyp-31A3, Cele\cyp-31A2, Cele\cyp-32A1" "Xtro\cyp26b1, Xtro\LOC100488227, Xtro\mgc108213, Xtro\cyp4b1, Xtro\cyp20a1, Xtro\cyp26a1, Xtro\LOC100487918, Xtro\cyp4v2, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\cyp4f2, Xtro\cyp19a1, Xtro\cyp4f22, Xtro\cyp2j2" "Mmus\Cyp4a14, Mmus\Cyp4f37, Mmus\Cyp4a10, Mmus\Cyp4f14, Mmus\Cyp4b1, Mmus\Cyp3a57, Mmus\Cyp4f39, Mmus\Cyp4f40, Mmus\Cyp20a1, Mmus\Cyp4v3, Mmus\Cyp4a12a, Mmus\Cyp3a41b, Mmus\Cyp3a11, Mmus\Cyp4a31, Mmus\Cyp4f15, Mmus\Cyp4f16, Mmus\Cyp3a41a, Mmus\Cyp3a13, Mmus\Cyp3a25, Mmus\Cyp26b1, Mmus\Cyp4a32, Mmus\Cyp3a59, Mmus\Cyp26c1, Mmus\Cyp19a1, Mmus\Cyp4f18, Mmus\Cyp3a16, Mmus\Cyp46a1, Mmus\Cyp26a1, Mmus\Cyp4a12b, Mmus\Cyp4a29, Mmus\Cyp3a44, Mmus\Cyp4f13, Mmus\Cyp4f17, Mmus\Cyp4x1, Mmus\Cyp4a30b" "Hsap\CYP4Z1, Hsap\CYP4V2, Hsap\CYP3A4, Hsap\CYP4F11, Hsap\CYP4F2, Hsap\CYP26B1, Hsap\CYP26C1, Hsap\CYP20A1, Hsap\CYP4F8, Hsap\CYP4F22, Hsap\CYP26A1, Hsap\CYP4F12, Hsap\CYP4X1, Hsap\CYP46A1, Hsap\CYP4F3, Hsap\CYP4B1, Hsap\CYP3A43, Hsap\CYP4A11, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\CYP19A1, Hsap\CYP4A22" viable FBgn0040211 hgo "homogentisate 1,2-dioxygenase" http://flybase.org/reports/FBgn0040211 protein_coding_gene "homogentisate 1,2-dioxygenase activity ; GO:0004411 | inferred from electronic annotation with InterPro:IPR005708" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005708 L-phenylalanine catabolic process ; GO:0006559 | inferred from electronic annotation with InterPro:IPR005708 tyrosine metabolic process ; GO:0006570 | inferred from electronic annotation with InterPro:IPR005708 - "CG4779, hgo" "IPR005708:Homogentisate 1,2-dioxygenase, IPR011051:RmlC-like cupin domain, IPR014710:RmlC-like jelly roll fold" CG4779 11-Aug-17 DroID_v2017_08 Drer\hgd - Cele\hgo-1 Xtro\hgd Mmus\Hgd Hsap\HGD viable FBgn0038157 CG12538 - http://flybase.org/reports/FBgn0038157 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12538 - CG12538 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC14527 E 0.046437574 0.110228914 -0.08017396 2.479050407 0.728833408 0.372081463 FBgn0085190 CG34161 - http://flybase.org/reports/FBgn0085190 protein_coding_gene acylphosphatase activity ; GO:0003998 | inferred from biological aspect of ancestor with PANTHER:PTN000003030 - - CG34161 "IPR017968:Acylphosphatase, conserved site, IPR001792:Acylphosphatase-like domain, IPR020456:Acylphosphatase" CG34161 11-Aug-17 DroID_v2017_08 "Drer\acyp1, Drer\acyp2" - - "Xtro\acyp1, Xtro\acyp2" "Mmus\Acyp2, Mmus\Acyp1" "Hsap\ACYP1, Hsap\ACYP2" FBgn0069111 mus219 mutagen-sensitive 219 http://flybase.org/reports/FBgn0069111 gene - - - mus219 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0085244 CG34215 - http://flybase.org/reports/FBgn0085244 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from biological aspect of ancestor with PANTHER:PTN002219240 - CG34215 IPR029277:Single domain Von Willebrand factor type C domain CG34215 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000641 fc faulty chaetae http://flybase.org/reports/FBgn0000641 - gene - - - fc - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile,recessive" "macrochaeta,scutellar bristle" FBgn0261728 EC666 - http://flybase.org/reports/FBgn0261728 gene - - - EC666 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during third instar larval stage" FBgn0030132 CG12067 - http://flybase.org/reports/FBgn0030132 protein_coding_gene - - - CG12067 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023474 alm almond http://flybase.org/reports/FBgn0023474 - gene - - - alm - - 11-Aug-17 DroID_v2017_08 - - - - - - visible pigment cell FBgn0039740 ZIPIC Zinc-finger protein interacting with CP190 http://flybase.org/reports/FBgn0039740 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Cp190 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay" polytene chromosome ; GO:0005700 | inferred from direct assay "ZIPIC, CG7928" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG7928 11-Aug-17 DroID_v2017_08 - Scer\AZF1 Cele\Y55F3AM.14 "Xtro\prdm15, Xtro\znf654" Mmus\Zfp654 "Hsap\ZNF654, Hsap\CTCFL" "partially lethal - majority die,some die during pupal stage" FBgn0266689 CR45179 - http://flybase.org/reports/FBgn0266689 non_protein_coding_gene - - - CR45179 - CR45179 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262149 CR42875 - http://flybase.org/reports/FBgn0262149 non_protein_coding_gene - - - CR42875 - CR42875 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060437 l(3)S125011 lethal (3) S125011 http://flybase.org/reports/FBgn0060437 gene - - - "1250/11, l(3)S125011" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0014072 TART-element\pol TART-open reading frame 2 http://flybase.org/reports/FBgn0014072 - transposable_element_gene - - - "RT, ORF2, TART-element\ORF2, TART-repeat\ORF2, TART-element\pol, TART ORF2, TART-RT" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004774 l(3)91Cd lethal (3) 91Cd http://flybase.org/reports/FBgn0004774 - gene - - - "l(3)CR3, l(3)91Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039039 lmd lame duck http://flybase.org/reports/FBgn0039039 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with UniProt:Q61602 inferred from sequence or structural similarity with UniProtKB:P10070 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay inferred from mutant phenotype" "muscle organ development ; GO:0007517 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with UniProt:Q61602 inferred from sequence or structural similarity with UniProtKB:P10070 somatic muscle development ; GO:0007525 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype muscle organ development ; GO:0007517 | traceable author statement regulation of hormone levels ; GO:0010817 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "minc, gfl, Lmd, CG4677, K, anon-EST:CL2d4, lmd, LMD" "IPR013087:Zinc finger C2H2-type, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4677 11-Aug-17 DroID_v2017_08 "Drer\klf9, Drer\glis2b, Drer\aaas, Drer\glis3, Drer\LOC100333406, Drer\glis2a" Scer\MIG2 "Cele\tra-1, Cele\M03D4.4" "Xtro\glis3, Xtro\glis2, Xtro\aaas" "Mmus\Glis3, Mmus\Glis1, Mmus\Gli2, Mmus\Gli3, Mmus\Aaas, Mmus\Gli1, Mmus\Glis2" "Hsap\GLI1, Hsap\GLIS1, Hsap\GLI2, Hsap\AAAS, Hsap\GLIS3, Hsap\GLI3, Hsap\GLIS2" embryonic stage | late mesoderm

"lethal,viable,visible" "embryonic somatic muscle,presumptive embryonic/larval muscle system,A1-7 dorsal acute muscle 1,embryonic/larval pericardial cell,supernumerary,muscle founder cell,embryonic myoblast,pharyngeal muscle,embryonic visceral muscle,trichogen cell" FBgn0015463 l(2)37Dk lethal (2) 37Dk http://flybase.org/reports/FBgn0015463 - gene - - - "l(2)E144,M, l(2)37Dk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037737 Pnn Pinin http://flybase.org/reports/FBgn0037737 protein_coding_gene - "cell adhesion ; GO:0007155 | inferred from biological aspect of ancestor with PANTHER:PTN000295178 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" exon-exon junction complex ; GO:0035145 | inferred from biological aspect of ancestor with PANTHER:PTN000295178 cell-cell junction ; GO:0005911 | inferred from biological aspect of ancestor with PANTHER:PTN000295178 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG8383, Pnn, dPnn, FBgn0037737, Pinin" IPR006786:Pinin/SDK/MemA protein CG8383 11-Aug-17 DroID_v2017_08 Drer\pnn - Cele\R186.7 Xtro\pnn Mmus\Pnn Hsap\PNN viable FBgn0260316 GSd479 - http://flybase.org/reports/FBgn0260316 gene - - - GSd479 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053811 His-Psi:CR33811 His-Psi:CR33811 http://flybase.org/reports/FBgn0053811 pseudogene_attribute - - - "CR33811, His-Psi:CR33811" - CR33811 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028024 l(3)S103616 lethal (3) S103616 http://flybase.org/reports/FBgn0028024 gene - - - "1036/16, l(3)S103616" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003369 sg shortened wing http://flybase.org/reports/FBgn0003369 - gene - - - sg - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,wing vein" FBgn0261363 PPO3 Prophenoloxidase 3 http://flybase.org/reports/FBgn0261363 protein_coding_gene L-DOPA monooxygenase activity ; GO:0036263 | inferred from direct assay dopamine monooxygenase activity ; GO:0036264 | inferred from direct assay dopamine metabolic process ; GO:0042417 | inferred by curator from GO:0036264 melanotic encapsulation of foreign target ; GO:0035011 | inferred from genetic interaction with PPO2 extracellular region ; GO:0005576 | inferred from direct assay "Dox-A3, DmePPO3, CG2952, proPO59, PPO3, Pro-PO3, CG42640, ProPO59" "IPR014756:Immunoglobulin E-set, IPR013788:Hemocyanin/hexamerin, IPR005204:Hemocyanin, N-terminal, IPR000896:Hemocyanin/hexamerin middle domain, IPR008922:Uncharacterised domain, di-copper centre, IPR002227:Tyrosinase copper-binding domain, IPR005203:Hemocyanin, C-terminal" CG42640 11-Aug-17 DroID_v2017_08 Drer\tyrp1a - Cele\srj-53 - - - "melanotic mass phenotype,viable" melanotic mass FBgn0040567 CG12332 - http://flybase.org/reports/FBgn0040567 protein_coding_gene - - - CG12332 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002641 mal maroon-like http://flybase.org/reports/FBgn0002641 - protein_coding_gene molybdenum ion binding ; GO:0030151 | inferred from electronic annotation with InterPro:IPR005302 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR005302 Mo-molybdopterin cofactor sulfurase activity ; GO:0008265 | inferred from sequence or structural similarity with UniProtKB:Q96EN8 Mo-molybdopterin cofactor sulfurase activity ; GO:0008265 | inferred from mutant phenotype Mo-molybdopterin cofactor biosynthetic process ; GO:0006777 | inferred from electronic annotation with InterPro:IPR028886 molybdopterin cofactor metabolic process ; GO:0043545 | inferred from sequence or structural similarity with UniProtKB:Q96EN8 molybdopterin cofactor metabolic process ; GO:0043545 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype - "ma-l, bz, 5, CG1692, mal, SRF" "IPR000192:Aminotransferase class V domain, IPR005302:Molybdenum cofactor sulfurase, C-terminal, IPR005303:MOSC, N-terminal beta barrel, IPR011037:Pyruvate kinase-like, insert domain, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR028886:Molybdenum cofactor sulfurase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG1692 11-Aug-17 DroID_v2017_08 Drer\mocos Scer\BNA5 Cele\mocs-1 - Mmus\Mocos Hsap\MOCOS "viable,fertile,eye color defective,male fertile,male,male sterile,chemical sensitive,recessive" "pigment cell,Malpighian tubule" FBgn0037431 CG17917 - http://flybase.org/reports/FBgn0037431 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17917 "IPR001858:Phosphatidylethanolamine-binding, conserved site, IPR008914:Phosphatidylethanolamine-binding protein" CG17917 11-Aug-17 DroID_v2017_08 "Drer\pebp1, Drer\mrpl38" "Scer\MRPL35, Scer\TFS1, Scer\YLR179C" "Cele\Y69E1A.5, Cele\F40A3.3" "Xtro\mrpl38, Xtro\pebp1, Xtro\pebp4" "Mmus\Pbp2, Mmus\Pebp4, Mmus\Mrpl38, Mmus\Pebp1" "Hsap\PEBP1, Hsap\MRPL38, Hsap\PEBP4" "viable,fertile" FBgn0035434 Drsl5 Drosomycin-like 5 http://flybase.org/reports/FBgn0035434 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro5, CG10812, Dro-G, BcDNA:GH09576, Drs-lG, dro5, Drsl5, dmy5" "IPR003614:Knottin, scorpion toxin-like" CG10812 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052039 CG32039 - http://flybase.org/reports/FBgn0052039 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH02734, BcDNA:RE03722, CG32039" IPR031632:Small VCP/p97-interacting protein CG32039 11-Aug-17 DroID_v2017_08 Drer\si:ch73-147o17.1 - Cele\T28C6.7 - Mmus\Svip Hsap\SVIP viable FBgn0022222 l(2)k03205 lethal (2) k03205 http://flybase.net/reports/FBgn0022222.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0262552 Mod(GMroX1)149 - http://flybase.org/reports/FBgn0262552 gene - - - Mod(GMroX1)149 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266307 CR44972 - http://flybase.org/reports/FBgn0266307 non_protein_coding_gene - - - CR44972 - CR44972 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035806 PGRP-SD Peptidoglycan recognition protein SD http://flybase.org/reports/FBgn0035806 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues innate immune response ; GO:0045087 | inferred from electronic annotation with InterPro:IPR017331 peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype innate immune response ; GO:0045087 | non-traceable author statement defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype positive regulation of peptidoglycan recognition protein signaling pathway ; GO:0061059 | inferred from mutant phenotype inferred from genetic interaction with PGRP-LC detection of peptidoglycan ; GO:0032499 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG7496, PGRP-SD, Dm PGRP-SD, pgrp-sd" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR017331:Peptidoglycan recognition protein, PGRP-S" CG7496 11-Aug-17 DroID_v2017_08 "Drer\pglyrp6, Drer\pglyrp5, Drer\pglyrp2" - - "Xtro\pglyrp1, Xtro\pglyrp2, Xtro\pglyrp1" "Mmus\Pglyrp3, Mmus\Pglyrp4, Mmus\Pglyrp2, Mmus\Pglyrp1" "Hsap\PGLYRP4, Hsap\PGLYRP2, Hsap\PGLYRP3, Hsap\PGLYRP1" "viable,fertile,immune response defective" FBgn0013492 l(1)90 lethal (1) 90 http://flybase.org/reports/FBgn0013492 - gene - - - "l90, l(1)90" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267719 CR46052 - http://flybase.org/reports/FBgn0267719 non_protein_coding_gene - - - CR46052 - CR46052 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000625 eyg eyegone http://flybase.org/reports/FBgn0000625 FBgn0011647 protein_coding_gene "RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement" compound eye development ; GO:0048749 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | traceable author statement antennal development ; GO:0007469 | inferred from mutant phenotype notum development ; GO:0007477 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "lun, Bk27, BK27, CG10488, eyg, Eyg, EYG" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain" CG10488 11-Aug-17 DroID_v2017_08 "Drer\pax3a, Drer\mxtx2, Drer\mxtx1, Drer\pax3b, Drer\mixl1, Drer\pax6b, Drer\pax4, Drer\pax7b" - Cele\eyg-1 "Xtro\bix1.1, Xtro\sia1, Xtro\mixer, Xtro\pax7, Xtro\pax6, Xtro\mix1, Xtro\pax3" "Mmus\Pax3, Mmus\Pax4, Mmus\Mixl1, Mmus\Cphx1, Mmus\Duxbl1, Mmus\Duxbl2, Mmus\Pax7, Mmus\Duxbl3, Mmus\Pax6, Mmus\Cphx3" "Hsap\PAX3, Hsap\DUX4, Hsap\PAX6, Hsap\PAX7, Hsap\DUXA, Hsap\MIXL1, Hsap\PAX4" " embryonic stage , larval stage | third instar , embryonic stage | stage >=11 , larval stage | second instar-- L | third instar " " adult eye primordium

, ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, salivary gland body primordium

, eye disc

, embryonic head | restricted

, eye disc | dorsal && morphogenetic furrow | anterior to

, eye disc | anterior

, antennal disc | central

, embryonic/larval posterior spiracle | vicinity of

, epidermis | segmentally repeated

" larval stage | third instar dorsal mesothoracic disc | restricted

"lethal,recessive,cell growth defective,somatic clone,lethal - all die before end of pupal stage,visible,some die during pupal stage,viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,semidominant,partially lethal - majority die,increased cell death,planar polarity defective,hyperplasia" "thorax,eye disc,eye-antennal disc,head,cell non-autonomous,somatic clone,eye,retina,adult head,adult thorax,dorsocentral bristle,mesothoracic tergum,microchaeta,embryonic/larval salivary gland duct,salivary gland imaginal ring,photoreceptor cell,ectopic,ventral,eye | pharate adult stage,thorax | pharate adult stage,supernumerary,wing disc,head | pharate adult stage,scutum,scutellum,macrochaeta,macrochaeta & scutumMS248,macrochaeta & scutum455.2,macrochaeta & scutumush-MD751,macrochaeta & scutumpnr-MD237,macrochaeta & scutumMD-638,wing,adult cuticle,proximal,heat sensitive,trichogen cell" FBgn0037251 CG9804 - http://flybase.org/reports/FBgn0037251 protein_coding_gene "octanoyltransferase activity ; GO:0016415 | inferred from electronic annotation with InterPro:IPR000544, InterPro:IPR020605 lipoyl(octanoyl) transferase activity ; GO:0033819 | inferred from sequence or structural similarity with UniProtKB:Q9SXP7" "lipoate biosynthetic process ; GO:0009107 | inferred from electronic annotation with InterPro:IPR000544, InterPro:IPR020605 protein lipoylation ; GO:0009249 | inferred from sequence or structural similarity with UniProtKB:Q9SXP7" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000544, InterPro:IPR020605" CG9804 "IPR000544:Octanoyltransferase, IPR004143:Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain, IPR020605:Octanoyltransferase, conserved site" CG9804 11-Aug-17 DroID_v2017_08 Drer\lipt2 Scer\LIP2 Cele\lpl-1 Xtro\lipt2 Mmus\Lipt2 Hsap\LIPT2 viable FBgn0066122 E(sda)M E(sda)M http://flybase.org/reports/FBgn0066122 gene - - - "E(sda)M, Line M" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004193 snRNA:U2:84Ca small nuclear RNA U2 at 84Ca http://flybase.org/reports/FBgn0004193 "FBgn0003919, FBgn0003924" snRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "U2 snRNA, snRNA:U2, U2snRNA84Ca, U2snRNA, snRNA:U2:84Ca, U2, dU2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065531 l(2)SH1108 lethal (2) SH1108 http://flybase.org/reports/FBgn0065531 gene - - - "l(2)SH1108, l(2)SH2 1108" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045054 fs(1)217 female sterile (1) 217 http://flybase.org/reports/FBgn0045054 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)217 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg chamber,follicle cell" FBgn0037899 RpL24-like Ribosomal protein L24-like http://flybase.org/reports/FBgn0037899 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype assembly of large subunit precursor of preribosome ; GO:1902626 | inferred from biological aspect of ancestor with PANTHER:PTN000846433 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000846433 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "RpL24-like, CG6764" "IPR000988:Ribosomal protein L24e-related, IPR011017:TRASH domain, IPR023442:Ribosomal protein L24e, conserved site" CG6764 11-Aug-17 DroID_v2017_08 Drer\rsl24d1 Scer\RLP24 Cele\rpl-24.2 Xtro\rsl24d1 Mmus\Rsl24d1 Hsap\RSL24D1 FBgn0260661 U5-40k - http://flybase.org/reports/FBgn0260661 protein_coding_gene - - - U5-40k - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266844 CR45306 - http://flybase.org/reports/FBgn0266844 non_protein_coding_gene - - - CR45306 - CR45306 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065393 l(2)SH1625 lethal (2) SH1625 http://flybase.org/reports/FBgn0065393 gene - - - "l(2)SH1625, l(2)SH2 1625" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044472 EP1592 EP1592 http://flybase.org/reports/FBgn0044472 gene - - - EP1592 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0013999 Op29 Ovary protein-29kD http://flybase.org/reports/FBgn0013999 - gene - - gap junction ; GO:0005921 | inferred from direct assay "Dop29, Op29" - - 11-Aug-17 DroID_v2017_08 - - - - - - oogenesis stage && adult stage | female ovary

FBgn0082375 EP1457 EP1457 http://flybase.org/reports/FBgn0082375 gene - - - EP1457 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0264420 FCO-E - http://flybase.org/reports/FBgn0264420 gene - - - FCO-E - - 11-Aug-17 DroID_v2017_08 - - - - - - "increased cell death,somatic clone" "follicle cell,somatic clone" FBgn0044406 Scim21 Sensitized chromosome inheritance modifier 21 http://flybase.org/reports/FBgn0044406 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0032974 CG3651 - http://flybase.org/reports/FBgn0032974 protein_coding_gene - - - CG3651 - CG3651 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027775 anon-69Da anon-69Da http://flybase.org/reports/FBgn0027775 - non_protein_coding_gene - - - anon-69Da - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027207 l(1)G0394 lethal (1) G0394 http://flybase.org/reports/FBgn0027207 - gene - - - l(1)G0394 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0013567 l(3)78Ac lethal (3) 78Ac http://flybase.org/reports/FBgn0013567 - gene - - - l(3)78Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053548 SmydA-8 "SET and MYND domain containing, arthropod-specific, member 8" http://flybase.org/reports/FBgn0053548 protein_coding_gene S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from sequence or structural similarity with SGD:S000001250 histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 histone lysine methylation ; GO:0034968 | inferred from sequence or structural similarity with SGD:S000001250 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with SGD:S000001250 "Msta, EG:103B4.4, CG18033, CG32799, EG:103B4.5, CG32800, CG33548, MSTA, SmydA-8, msta" IPR001214:SET domain CG33548 11-Aug-17 DroID_v2017_08 "Drer\smyd2b, Drer\smyd3, Drer\smyd1a, Drer\smyd1b, Drer\smyd4, Drer\smyd2a" "Scer\SET5, Scer\SET6" - "Xtro\smyd4, Xtro\smyd5, Xtro\smyd1" "Mmus\Smyd3, Mmus\Smyd1, Mmus\Smyd2, Mmus\Smyd4, Mmus\Smyd5" "Hsap\SMYD5, Hsap\SMYD4, Hsap\SMYD1, Hsap\SMYD2, Hsap\SMYD3" viable FBgn0267770 CR46101 - http://flybase.org/reports/FBgn0267770 non_protein_coding_gene - - - CR46101 - CR46101 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033708 CG8850 - http://flybase.org/reports/FBgn0033708 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model amino acid transmembrane import ; GO:0044745 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model "CG8850, DmNAT4" IPR000175:Sodium:neurotransmitter symporter CG8850 11-Aug-17 DroID_v2017_08 "Drer\slc6a19b, Drer\si:ch211-132b12.2, Drer\zgc:174946, Drer\si:ch211-132b12.6, Drer\si:ch211-132b12.3, Drer\si:ch211-132b12.1, Drer\slc6a8, Drer\slc6a16b, Drer\slc6a9, Drer\si:ch211-117c9.5, Drer\slc6a5, Drer\slc6a14, Drer\slc6a13l, Drer\slc6a15, Drer\slc6a4b, Drer\zgc:158225, Drer\slc6a1b, Drer\slc6a6b, Drer\slc6a17, Drer\slc6a11a, Drer\slc6a13, Drer\slc6a13, Drer\slc6a4a, Drer\slc6a6a, Drer\slc6a1a, Drer\slc6a18, Drer\slc6a19a.1, Drer\slc6a2, Drer\slc6a16a, Drer\slc6a1l" - "Cele\snf-7, Cele\dat-1, Cele\snf-5, Cele\mod-5, Cele\snf-12, Cele\snf-3, Cele\snf-2, Cele\snf-11, Cele\snf-9, Cele\snf-6" "Xtro\slc6a1, Xtro\slc6a8, Xtro\slc6a3, Xtro\slc6a12, Xtro\slc6a4, Xtro\slc6a17, Xtro\slc6a16, Xtro\slc6a9, Xtro\slc6a14.2, Xtro\slc6a7, Xtro\LOC100127682, Xtro\slc6a19, Xtro\slc6a6, Xtro\slc6a5, Xtro\slc6a2, Xtro\slc6a13, Xtro\slc6a15" "Mmus\Slc6a13, Mmus\Slc6a2, Mmus\Slc6a7, Mmus\Slc6a20a, Mmus\Slc6a6, Mmus\Slc6a4, Mmus\Slc6a3, Mmus\Slc6a5, Mmus\Slc6a14, Mmus\Slc6a8, Mmus\Slc6a19, Mmus\Slc6a1, Mmus\Slc6a12, Mmus\Slc6a11, Mmus\Slc6a9, Mmus\Slc6a15, Mmus\Slc6a18, Mmus\Slc6a17, Mmus\Slc6a20b" "Hsap\SLC6A17, Hsap\SLC6A12, Hsap\SLC6A9, Hsap\SLC6A8, Hsap\SLC6A2, Hsap\SLC6A11, Hsap\SLC6A1, Hsap\SLC6A13, Hsap\SLC6A20, Hsap\SLC6A19, Hsap\SLC6A6, Hsap\SLC6A15, Hsap\SLC6A14, Hsap\SLC6A3, Hsap\SLC6A18, Hsap\SLC6A5, Hsap\SLC6A4" FBgn0063780 accord2\pol accord2 element pol http://flybase.org/reports/FBgn0063780 transposable_element_gene - - - "qbert\pol, accord2\pol" "IPR026523:Paraneoplastic antigen Ma, IPR000477:Reverse transcriptase domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030107 CG15370 - http://flybase.org/reports/FBgn0030107 protein_coding_gene - - - CG15370 - CG15370 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0005436 l(1)v47 lethal (1) v47 http://flybase.org/reports/FBgn0005436 - gene - - - "l(1)47, l(1)v47" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086718 aga angina http://flybase.org/reports/FBgn0086718 gene - - - aga - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060417 l(3)S129310b lethal (3) S129310b http://flybase.org/reports/FBgn0060417 gene - - - "1293/10, l(3)S129310b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0016947 tilD touch insensitive larva D http://flybase.org/reports/FBgn0016947 - gene - - - tilD - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective,visible,somatic clone,paralytic" "macrochaeta,somatic clone,leg" FBgn0017423 anon-70Ca anon-70Ca http://flybase.org/reports/FBgn0017423 - gene - - - "t2, anon-70Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage&&larval stage && pupal stage , egg stage | unfertilized egg " unfertilized egg

FBgn0038673 CG14286 - http://flybase.org/reports/FBgn0038673 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14286, 14286" IPR029274:Protein of unknown function DUF4615 CG14286 11-Aug-17 DroID_v2017_08 Drer\zgc:112185 - - Xtro\c8orf33 Mmus\1110038F14Rik Hsap\C8orf33 "viable,fertile" FBgn0060694 l(3)S073015 lethal (3) S073015 http://flybase.org/reports/FBgn0060694 gene - - - "0730/15, l(3)S073015" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0067866 Mod(Prat:bw)3-9 Mod(Prat:bw)3-9 http://flybase.org/reports/FBgn0067866 gene - - - "Mod-3-9, Mod(Prat:bw)3-9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0004623 Gbeta76C G protein beta-subunit 76C http://flybase.org/reports/FBgn0004623 FBgn0016651 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Gγ30A phototransduction ; GO:0007602 | inferred from direct assay rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay phototransduction ; GO:0007602 | inferred from mutant phenotype activation of phospholipase C activity ; GO:0007202 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay rhabdomere ; GO:0016028 | traceable author statement heterotrimeric G-protein complex ; GO:0005834 | inferred from direct assay "Gbeta76C, Gbe, Gbeta, G[q], Gbetae, DGqbeta, G[[beta]]e, gbe, G[[beta]], Gbeta[[e]], Gqbeta, CG8770, Galpha76C, Gbeta{e}, eye Gbeta, eGbeta, G[[beta76C]], G&bgr76C, Gbeta76c" "IPR017986:WD40-repeat-containing domain, IPR001632:G-protein, beta subunit, IPR001680:WD40 repeat, IPR016346:Guanine nucleotide-binding protein, beta subunit, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG8770 11-Aug-17 DroID_v2017_08 "Drer\gnb1a, Drer\gnb5a, Drer\gnb3a, Drer\gnb3b, Drer\gnb4a, Drer\gnb4b, Drer\gnb5b, Drer\gnb2, Drer\gnb1b" Scer\STE4 "Cele\gpb-2, Cele\gpb-1, Cele\npp-20" "Xtro\gnb5, Xtro\gnb1, Xtro\gnb3, Xtro\gnb4" "Mmus\Gnb3, Mmus\Gnb2, Mmus\Gnb4, Mmus\Gnb1" "Hsap\GNB5, Hsap\GNB4, Hsap\GNB1, Hsap\GNB3, Hsap\GNB2" adult stage " adult head

, eye

" adult stage " eye

, photoreceptor cell

, medulla

, lamina

" "wild-type,neurophysiology defective,viable" photoreceptor cell FBgn0051365 CG31365 - http://flybase.org/reports/FBgn0051365 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG4639, CG31365" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG31365 11-Aug-17 DroID_v2017_08 "Drer\zbtb24, Drer\zbtb8b, Drer\zbtb46, Drer\mynn, Drer\zbtb16b, Drer\zbtb17, Drer\zbtb18, Drer\hic2, Drer\zbtb16a, Drer\hic1, Drer\zbtb14, Drer\hic1l, Drer\zbtb49, Drer\bcl6ab, Drer\zbtb7a, Drer\zbtb1" Scer\ZAP1 "Cele\unc-98, Cele\klf-3" "Xtro\zbtb49, Xtro\zbtb18, Xtro\gzf1, Xtro\zbtb26, Xtro\zbtb7c, Xtro\hic2, Xtro\znf630, Xtro\zbtb11, Xtro\zbtb3, Xtro\bcl6, Xtro\hic1, Xtro\zbtb7b, Xtro\znf238.2, Xtro\zbtb14, Xtro\zbtb40, Xtro\zbtb8b" "Mmus\Zbtb26, Mmus\Zscan4d, Mmus\Zbtb7b, Mmus\Bcl6b, Mmus\Zfp719, Mmus\Zbtb7c, Mmus\Zbtb46, Mmus\Zbtb17, Mmus\Zscan4c, Mmus\Hic2, Mmus\Bcl6, Mmus\Zfp131, Mmus\Zbtb14, Mmus\Zbtb18, Mmus\Zbtb49, Mmus\Zbtb3, Mmus\Zbtb24, Mmus\Mynn, Mmus\Zfp341, Mmus\Zbtb7a, Mmus\Zbtb42" "Hsap\ZBTB48, Hsap\ZBTB8B, Hsap\HIC2, Hsap\ZBTB17, Hsap\ZBTB18, Hsap\ZBTB3, Hsap\ZBTB16, Hsap\ZBTB7A, Hsap\GZF1, Hsap\ZNF302, Hsap\ZNF341, Hsap\ZBTB43, Hsap\ZBTB42, Hsap\BCL6, Hsap\ZBTB46, Hsap\MYNN, Hsap\ZBTB49, Hsap\ZBTB24, Hsap\ZNF131, Hsap\ZBTB7C, Hsap\ZBTB11, Hsap\ZBTB14, Hsap\ZBTB7B, Hsap\ZBTB5, Hsap\BCL6B, Hsap\ZNF83, Hsap\ZBTB26, Hsap\ZBTB2" viable FBgn0060358 l(3)S140612 lethal (3) S140612 http://flybase.org/reports/FBgn0060358 gene - - - "1406/12, l(3)S140612" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039681 CG7582 - http://flybase.org/reports/FBgn0039681 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012506 CG7582 IPR012506:YhhN-like CG7582 11-Aug-17 DroID_v2017_08 "Drer\tmem86a, Drer\tmem86b" - Cele\M176.4 Xtro\tmem86a "Mmus\Tmem86a, Mmus\Tmem86b" "Hsap\TMEM86A, Hsap\TMEM86B" viable FBgn0259196 CG42300 - http://flybase.org/reports/FBgn0259196 protein_coding_gene SUMO transferase activity ; GO:0019789 | inferred from electronic annotation with InterPro:IPR026846 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181 double-strand break repair via homologous recombination ; GO:0000724 | inferred from electronic annotation with InterPro:IPR026846 Smc5-Smc6 complex ; GO:0030915 | inferred from electronic annotation with InterPro:IPR026846 "CG42300, CG32584, CG18620" "IPR004181:Zinc finger, MIZ-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR026846:E3 SUMO-protein ligase Nse2 (Mms21)" CG42300 11-Aug-17 DroID_v2017_08 Drer\nsmce2 Scer\MMS21 Cele\ZK1248.11 - Mmus\Nsmce2 Hsap\NSMCE2 "viable,visible,fertile" tormogen cell FBgn0030932 Ggt-1 gamma-glutamyl transpeptidase http://flybase.org/reports/FBgn0030932 protein_coding_gene glutathione hydrolase activity ; GO:0036374 | inferred from sequence or structural similarity with HGNC:4250 inferred from direct assay glutathione catabolic process ; GO:0006751 | inferred from electronic annotation with InterPro:IPR000101 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern glutathione metabolic process ; GO:0006749 | inferred from direct assay response to light stimulus ; GO:0009416 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "Ggt-1, GGT-1, CG6461" "IPR000101:Gamma-glutamyltranspeptidase, IPR029055:Nucleophile aminohydrolases, N-terminal" CG6461 11-Aug-17 DroID_v2017_08 "Drer\ggt1a, Drer\si:ch73-236c18.3, Drer\ggt5a, Drer\ggt1b, Drer\si:ch73-59p9.2, Drer\si:dkey-222h21.12, Drer\ggt5b, Drer\LOC103909498, Drer\ggt1l2.2" Scer\ECM38 "Cele\C53D5.5, Cele\Y97E10AR.2, Cele\H14N18.4, Cele\T19H12.6, Cele\Y7A9A.1, Cele\T03D8.6" "Xtro\ggt5, Xtro\ggt7, Xtro\ggt1" "Mmus\Ggt1, Mmus\Ggt5, Mmus\Ggt7, Mmus\Ggt6" "Hsap\GGT1, Hsap\GGTLC2, Hsap\GGT2, Hsap\GGT6, Hsap\GGT7, Hsap\GGT5, Hsap\GGTLC1" partially lethal - majority die FBgn0024638 l(2)k13525 lethal (2) k13525 http://flybase.org/reports/FBgn0024638 - gene - - - "135/25, l(2)k13525" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0036705 CG13723 - http://flybase.org/reports/FBgn0036705 protein_coding_gene - - - CG13723 - CG13723 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036317 CG10948 - http://flybase.org/reports/FBgn0036317 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "CT30663, cg10948, CG10948" "IPR000504:RNA recognition motif domain, IPR034140:Ecto-NOX disulfide-thiol exchanger, RNA recognition motif" CG10948 11-Aug-17 DroID_v2017_08 "Drer\enox1, Drer\enox2" - - Xtro\enox1 "Mmus\Enox2, Mmus\Enox1" "Hsap\ENOX2, Hsap\ENOX1" "fertile,viable,lethal,partially lethal - majority die" FBgn0005651 Mst59Da Male-specific transcript 59Da http://flybase.org/reports/FBgn0005651 - gene - - - Mst59Da - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043996 Su(rst)D121 Su(rst)D121 http://flybase.org/reports/FBgn0043996 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D121, Su(rst)D121" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0070041 3R-35-29 3R-35-29 http://flybase.org/reports/FBgn0070041 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-35-29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0000773 fs(1)A1187 female sterile (1) A1187 http://flybase.org/reports/FBgn0000773 - gene - - - "fs(1)1187, fs(1)A1187" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,non-rescuable maternal effect,heat sensitive,female sterile,recessive,mitotic cell cycle defective" blastoderm embryo FBgn0005300 mei-O81 meiotic from Ostiense 81 http://flybase.org/reports/FBgn0005300 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mei-O81 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive" spermatocyte & nuclear chromosome FBgn0043992 Su(rst)D49 Su(rst)D49 http://flybase.org/reports/FBgn0043992 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D49, Su(rst)D49" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028550 Atf3 Activating transcription factor 3 http://flybase.org/reports/FBgn0028550 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000837, InterPro:IPR004827 protein dimerization activity ; GO:0046983 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Jra sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR000837 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "EG:33C11.1, CG11405, dATF3, ATF3, Atf3, atf3, A3-3, DM11" "IPR000837:AP-1 transcription factor, IPR004827:Basic-leucine zipper domain" CG11405 11-Aug-17 DroID_v2017_08 "Drer\creb5b, Drer\atf2, Drer\fosb, Drer\jdp2a, Drer\fosl2, Drer\atf7b, Drer\batf3, Drer\atf7a, Drer\atf3, Drer\si:ch211-59d15.4, Drer\si:ch211-153j24.3, Drer\jdp2b, Drer\fosl1b, Drer\fosab, Drer\fosaa, Drer\fosl1a, Drer\batf" "Scer\CST6, Scer\ACA1" "Cele\zip-11, Cele\fos-1" "Xtro\creb5, Xtro\atf7, Xtro\atf3, Xtro\atf2, Xtro\fosl1, Xtro\batf, Xtro\fosl2, Xtro\fosb, Xtro\fos" "Mmus\Fosl2, Mmus\Fosb, Mmus\Atf7, Mmus\Batf, Mmus\Atf3, Mmus\Jdp2, Mmus\Fosl1, Mmus\Batf3, Mmus\Batf2, Mmus\Creb5, Mmus\Atf2, Mmus\Fos" "Hsap\JDP2, Hsap\BATF, Hsap\FOSB, Hsap\ATF2, Hsap\FOSL1, Hsap\BATF3, Hsap\ATF3, Hsap\FOSL2, Hsap\FOS, Hsap\BATF2, Hsap\CREB5, Hsap\ATF7" "visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,lethal,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,female fertile,reduced,partially,recessive" "eye,adult cuticle,dorsal,adult abdomen,somatic clone,embryonic/larval fat body,lipid particle" FBgn0058464 CR40464 - http://flybase.org/reports/FBgn0058464 non_protein_coding_gene - - - CR40464 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044459 EP3373 EP3373 http://flybase.org/reports/FBgn0044459 gene - - - EP3373 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0052546 tRNA:Pro-CGG-2-1 transfer RNA:Proline-CGG 2-1 http://flybase.org/reports/FBgn0052546 tRNA_gene CCG codon-amino acid adaptor activity ; GO:0033424 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033424 cytosol ; GO:0005829 | inferred by curator from GO:0033424 "AE002593.trna10-ProCGG, tRNA:P:CGG:AE002593, CR32546, chrX.trna14-ProCGG, tRNA-Pro-CGG-2-1, tRNA:Pro-CGG-2-1, tRNA:CR32546, CCG" - CR32546 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260125 2L3574 - http://flybase.org/reports/FBgn0260125 gene - - - 2L3574 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030678 CG11679 - http://flybase.org/reports/FBgn0030678 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11679 IPR003734:Domain of unknown function DUF155 CG11679 11-Aug-17 DroID_v2017_08 Drer\rmnd1 "Scer\RMD8, Scer\MRX10, Scer\RMD1" Cele\ZK1010.2 Xtro\rmnd1 Mmus\Rmnd1 Hsap\RMND1 "viable,body color defective" mesothoracic tergum FBgn0052305 CG32305 - http://flybase.org/reports/FBgn0052305 protein_coding_gene guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924" "CG8970, AC, CG32305" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase" CG32305 11-Aug-17 DroID_v2017_08 "Drer\adcy1a, Drer\adcy7, Drer\adcy5, Drer\adcy6b, Drer\adcy6a, Drer\adcy2a, Drer\adcy1b, Drer\adcy8, Drer\adcy2b, Drer\adcy3a, Drer\si:ch211-132f19.7, Drer\si:dkey-206f10.1" - "Cele\acy-4, Cele\acy-2" "Xtro\dnajc27, Xtro\adcy4, Xtro\adcy7, Xtro\adcy6, Xtro\adcy1" "Mmus\Adcy7, Mmus\Adcy6, Mmus\Adcy8, Mmus\Adcy4, Mmus\Adcy1, Mmus\Adcy2, Mmus\Adcy5, Mmus\Adcy3" "Hsap\ADCY3, Hsap\ADCY5, Hsap\ADCY6, Hsap\ADCY4, Hsap\ADCY7, Hsap\ADCY8, Hsap\ADCY1, Hsap\ADCY2" viable FBgn0002188 l(3)63Aa lethal (3) 63Aa http://flybase.org/reports/FBgn0002188 - gene - - - l(3)63Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0030035 PIG-T Phosphatidylinositol glycan anchor biosynthesis class T http://flybase.org/reports/FBgn0030035 protein_coding_gene GPI-anchor transamidase activity ; GO:0003923 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000311103 attachment of GPI anchor to protein ; GO:0016255 | inferred from sequence or structural similarity with protein_id:BAB60854.1 attachment of GPI anchor to protein ; GO:0016255 | inferred from biological aspect of ancestor with PANTHER:PTN000311103 GPI-anchor transamidase complex ; GO:0042765 | inferred from biological aspect of ancestor with PANTHER:PTN000311103 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with protein_id:BAB60854.1 "Dm*AAF46367/27-522, CG11190, PIG-T" IPR007245:GPI transamidase component PIG-T CG11190 11-Aug-17 DroID_v2017_08 Drer\pigt Scer\GPI16 Cele\F17C11.7 Xtro\pigt Mmus\Pigt Hsap\PIGT "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015771 N::tor N::tor http://flybase.org/reports/FBgn0015771 - engineered_fusion_gene - - - N::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "microchaeta,precursor,wing disc" FBgn0030457 CG12096 - http://flybase.org/reports/FBgn0030457 protein_coding_gene - proteasome regulatory particle assembly ; GO:0070682 | inferred from biological aspect of ancestor with PANTHER:PTN000339132 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype "proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from biological aspect of ancestor with PANTHER:PTN000339132" "CG12096, 12096, S5b/PSMD5, dS5b, S5b" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR019538:26S proteasome non-ATPase regulatory subunit 5" CG12096 11-Aug-17 DroID_v2017_08 Drer\psmd5 - Cele\F35G12.12 Xtro\psmd5 Mmus\Psmd5 Hsap\PSMD5 "viable,fertile" FBgn0262455 mir-1 mir-1 stem loop http://flybase.org/reports/FBgn0262455 miRNA_gene - "cardiocyte differentiation ; GO:0035051 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from direct assay positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from genetic interaction with Ge-1, me31B muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype" - "miR-1, mir-1, dme-mir-1, MIR-1, CR43027, dmiR-1, DmiR-1, Mir-1, CR32958, transfrag 8, Mir1, mirR-1, MiR-1, miR1, dme-miR-1-3p, dme-miR-1" - CR43027 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0022983 rdgB::Rnor\PITPNA rdgB::Rnor\PITPNA http://flybase.org/reports/FBgn0022983 - engineered_fusion_gene - - - "rdgB::Rat\PITPNA, rdgB::Rnor\PITPNA" - - 11-Aug-17 DroID_v2017_08 - - - - - - "rhabdomere R5,rhabdomere R6,retina,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4" FBgn0085616 CG41326 - http://flybase.org/reports/FBgn0085616 protein_coding_gene - - - CG41326 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004128 l(2)43Cb lethal (2) 43Cb http://flybase.org/reports/FBgn0004128 FBgn0014246 gene - - - "43Cb, l(2)43Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052163 CG32163 - http://flybase.org/reports/FBgn0052163 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32163 "IPR016181:Acyl-CoA N-acyltransferase, IPR031165:Yjdj-type Gcn5-related N-acetyltransferase" CG32163 11-Aug-17 DroID_v2017_08 "Drer\im:6904045, Drer\natd1" - Cele\ZK1098.11 Xtro\natd1 Mmus\Natd1 Hsap\NATD1 viable DRSC21888 EK -1.004865896 0.362191192 3.828094224 0.167604634 -0.16325746 -1.502401665 FBgn0042198 CG16741 - http://flybase.org/reports/FBgn0042198 protein_coding_gene - - - "CG18463, CG16741" - CG16741 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004512 Mdr49 Multi drug resistance 49 http://flybase.org/reports/FBgn0004512 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 drug transmembrane transporter activity ; GO:0015238 | non-traceable author statement xenobiotic-transporting ATPase activity ; GO:0008559 | inferred from sequence or structural similarity with UniProtKB:Q00748 efflux transmembrane transporter activity ; GO:0015562 | inferred from sequence or structural similarity with UniProtKB:Q00748" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 drug transmembrane transport ; GO:0006855 | non-traceable author statement response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype response to toxic substance ; GO:0009636 | inferred from expression pattern germ cell migration ; GO:0008354 | inferred from mutant phenotype renal tubular secretion ; GO:0097254 | inferred from expression pattern xenobiotic transport ; GO:0042908 | inferred from sequence or structural similarity with UniProtKB:Q00748 ATP-binding cassette (ABC) transporter complex ; GO:0043190 | inferred from sequence or structural similarity with UniProtKB:Q00748 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q00748 integral component of plasma membrane ; GO:0005887 | non-traceable author statement "Mdr49, CG3879, Mes5, MDR49, MDR5, Dm5, mdr49, mrd49" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3879 11-Aug-17 DroID_v2017_08 "Drer\abcb11a, Drer\abcb8, Drer\abcb11b, Drer\abcb4, Drer\abcb3l1, Drer\abcb9, Drer\abcb5, Drer\abcb10" Scer\STE6 "Cele\haf-9, Cele\haf-2, Cele\pgp-7, Cele\haf-4, Cele\pgp-10, Cele\pgp-1, Cele\pgp-6, Cele\pgp-5, Cele\pgp-8, Cele\haf-7, Cele\haf-8, Cele\pgp-2, Cele\pgp-12, Cele\pgp-11, Cele\haf-1, Cele\haf-3, Cele\pgp-9, Cele\pgp-4, Cele\pgp-14, Cele\haf-6, Cele\pgp-13, Cele\pgp-3" "Xtro\LOC100494740, Xtro\abcb8" "Mmus\Abcb1a, Mmus\Abcb5, Mmus\Abcb4, Mmus\Abcb11, Mmus\Abcb1b, Mmus\Abcb10, Mmus\Abcb8, Mmus\Abcb9" "Hsap\ABCB1, Hsap\ABCB8, Hsap\ABCB5, Hsap\ABCB11, Hsap\ABCB10, Hsap\ABCB4" embryonic stage | cellular blastoderm mesoderm anlage

viable "germline cell,pole cell" FBgn0086418 l(3)CHb lethal (3) CHb http://flybase.org/reports/FBgn0086418 gene - - - l(3)CHb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020297 jockey\gag jockey gag http://flybase.org/reports/FBgn0020297 - transposable_element_gene - - - jockey\gag IPR006579:Pre-C2HC domain - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262333 mir-963 mir-963 stem loop http://flybase.org/reports/FBgn0262333 miRNA_gene - "regulation of feeding behavior ; GO:0060259 | inferred from genetic interaction with mir-959, mir-960, mir-961, mir-962, mir-964 immune response ; GO:0006955 | inferred from genetic interaction with mir-959, mir-960, mir-961, mir-962, mir-964" - "dme-mir-963, mir-963, CR43040, miR-963" - CR43040 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing FBgn0019929 Ser7 Ser7 http://flybase.org/reports/FBgn0019929 FBgn0030154 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type peptidase activity ; GO:0008236 | inferred from sequence or structural similarity serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP3, c-SP3, CG2045, SP#2, SP2, Ser7" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site, IPR022700:Proteinase, regulatory CLIP domain" CG2045 11-Aug-17 DroID_v2017_08 Drer\masp2 - "Cele\svh-1, Cele\try-1" - "Mmus\C1s2, Mmus\Klk1b9, Mmus\C1s1, Mmus\Klk1b1, Mmus\Klk1b5" "Hsap\C1S, Hsap\KLK1" viable FBgn0085679 CG41542 - http://flybase.org/reports/FBgn0085679 protein_coding_gene - - - CG41542 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052506 CG32506 - http://flybase.org/reports/FBgn0052506 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG32506 "IPR000195:Rab-GTPase-TBC domain, IPR004012:RUN domain" CG32506 11-Aug-17 DroID_v2017_08 "Drer\sgsm1b, Drer\sgsm1a, Drer\sgsm2" Scer\GYP7 Cele\tbc-8 "Xtro\sgsm2, Xtro\sgsm1" "Mmus\Sgsm2, Mmus\Sgsm1" "Hsap\SGSM2, Hsap\SGSM1" "viable,fertile" FBgn0025627 CG4194 - http://flybase.org/reports/FBgn0025627 - protein_coding_gene - - - "EG:22E5.6, CG4194" - CG4194 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002183 dre4 dre4 http://flybase.org/reports/FBgn0002183 FBgn0002182 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay nucleosome binding ; GO:0031491 | inferred from direct assay histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000360139 regulation of chromatin assembly or disassembly ; GO:0001672 | inferred from mutant phenotype DNA replication-independent nucleosome organization ; GO:0034724 | inferred from biological aspect of ancestor with PANTHER:PTN000360139 positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype FACT complex ; GO:0035101 | traceable author statement FACT complex ; GO:0035101 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Spt16, dSPT16, spt16, dspt16, DRE4/dSPT16, l(3)dre4, l(3)62Bg, CG1828, dre4, dSpt16, SPT16, Dre4, DRE4" "IPR000994:Peptidase M24, IPR013719:Domain of unknown function DUF1747, IPR013953:FACT complex subunit Spt16p/Cdc68p, IPR033825:FACT complex subunit SPT16, IPR029149:Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR029148:FACT complex subunit Spt16, N-terminal lobe domain" CG1828 11-Aug-17 DroID_v2017_08 Drer\supt16h Scer\SPT16 "Cele\F55A3.7, Cele\F55A3.3" Xtro\supt16h Mmus\Supt16 Hsap\SUPT16H "lethal,heat sensitive,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC08714 I -3.721266813 -1.380521877 -0.547079818 -0.614702853 -1.109159874 0.284282458 FBgn0046665 anon-38C.32 anon-38C.32 http://flybase.org/reports/FBgn0046665 gene - - - "38C.32, anon-38C.32" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002617 M(3)76A Minute (3) 76A http://flybase.org/reports/FBgn0002617 - gene - - - "M(3)S34, M(3)76A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022323 l(1)B22.5 lethal (1) B22.5 http://flybase.org/reports/FBgn0022323 - gene - - - "B22.5, l(1)B22.5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039703 CG7829 - http://flybase.org/reports/FBgn0039703 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP136, CG7829" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG7829 11-Aug-17 DroID_v2017_08 Drer\si:ch211-165b19.8 - "Cele\try-1, Cele\svh-1" - "Mmus\Prss55, Mmus\Cfd, Mmus\Prss53, Mmus\Prss36" "Hsap\PRSS36, Hsap\PRSS53, Hsap\CFD" viable FBgn0085723 CG41616 - http://flybase.org/reports/FBgn0085723 protein_coding_gene - - - CG41616 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264717 CR43985 - http://flybase.org/reports/FBgn0264717 non_protein_coding_gene - - - CR43985 - CR43985 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011106 l(1)Q67 lethal (1) Q67 http://flybase.org/reports/FBgn0011106 FBgn0010210 gene - - - l(1)Q67 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0042157 CG18834 - http://flybase.org/reports/FBgn0042157 protein_coding_gene - - - CG18834 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065233 l(2)SH2168 lethal (2) SH2168 http://flybase.org/reports/FBgn0065233 gene - - - l(2)SH2168 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261563 wb wing blister http://flybase.org/reports/FBgn0261563 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype digestive tract mesoderm development ; GO:0007502 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype basal lamina ; GO:0005605 | inferred from sequence or structural similarity basement membrane ; GO:0005604 | inferred from sequence or structural similarity "wb, l(2)br1, A1, l(2)34Fb, l(2)09437, CG15288, BEST:CK02229, BG:DS03792.2, CG32970, CG42677, alpha[[1,2]], CT35236, LM-A/alpha2, BG:DS03792.1, CK02229, DLAM, l34Fb, fus5, LanA1,2, &agr1,2Lan" "IPR000034:Laminin IV, IPR001791:Laminin G domain, IPR002049:Laminin EGF domain, IPR008211:Laminin, N-terminal, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR008979:Galactose-binding domain-like, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000742:EGF-like domain" CG42677 11-Aug-17 DroID_v2017_08 "Drer\ntn1b, Drer\lama4, Drer\lama2, Drer\ush2a, Drer\lama1, Drer\lamc3, Drer\lamc1, Drer\lama5, Drer\ntn5, Drer\ntn2" Scer\IMH1 Cele\lam-3 "Xtro\lama2, Xtro\lama3, Xtro\ntn3, Xtro\lama1, Xtro\lama5, Xtro\lamc2, Xtro\lama4, Xtro\lamc1, Xtro\ntn1" "Mmus\Lama4, Mmus\Ush2a, Mmus\Lamc2, Mmus\Lama2, Mmus\Lama3, Mmus\Lamc1, Mmus\Lamc3, Mmus\Ntn1, Mmus\Ntng1, Mmus\Lama1, Mmus\Lama5, Mmus\Ntn3" "Hsap\LAMA4, Hsap\LAMA5, Hsap\NTN1, Hsap\LAMA3, Hsap\LAMC3, Hsap\LAMC2, Hsap\NTNG1, Hsap\NTN3, Hsap\LAMC1, Hsap\USH2A, Hsap\LAMA1, Hsap\LAMA2" " embryonic stage | early , embryonic stage | stage >12 , embryonic stage | stage 14 , embryonic stage -- adult stage , embryonic stage | stage 9-11 , adult stage && oogenesis stage " "

ubiquitous , visceral mesoderm

, alary cell

, muscle attachment site | vicinity of

, oocyte

, nurse cell

" " larval stage | third instar , embryonic stage | stage >14 , embryonic stage | stage 14 , embryonic stage | stage 10 , embryonic stage | stage >=12 " " dorsal mesothoracic disc | restricted

, ventral nerve cord | dorsal

, muscle attachment site

, mesectoderm

, visceral mesoderm

" DRSC23003 K 1.318098992 1.740092199 FBgn0265697 CR44504 - http://flybase.org/reports/FBgn0265697 non_protein_coding_gene - - - "CR44504, pri-mir-6-3_mir-6-2_mir-6-1_mir-5_mir-4_mir-286_mir-3_mir-309" - CR44504 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015828 TfIIEalpha Transcription factor IIEalpha http://flybase.org/reports/FBgn0015828 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017919 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4650 inferred from sequence or structural similarity with SGD:S000001511 inferred from sequence or structural similarity with protein_id:CAA70050.2 transcription factor TFIIE complex ; GO:0005673 | inferred from sequence or structural similarity with HGNC:4650 inferred from sequence or structural similarity with SGD:S000001511 inferred from sequence or structural similarity with protein_id:CAA70050.2 transcription factor TFIIE complex ; GO:0005673 | inferred from physical interaction with TfIIEβ nucleus ; GO:0005634 | inferred from direct assay "TFIIE, TFIIEalpha, TFIIE-L, CG10415, dTFIIEL, dTFIIE-L, TfIIE, TfIIEalpha, TfIIEa" "IPR002853:Transcription initiation factor IIE subunit alpha, N-terminal, IPR017919:Transcription factor TFE/TFIIEalpha HTH domain, IPR024550:TFIIEalpha/SarR/Rpc3 HTH domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR021600:Transcription factor TFIIE alpha subunit, C-terminal, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10415 11-Aug-17 DroID_v2017_08 Drer\gtf2e1 Scer\TFA1 Cele\ZK550.4 "Xtro\gtf2e1, Xtro\gtf2e1.2" Mmus\Gtf2e1 Hsap\GTF2E1 lethal FBgn0086052 snoRNA:Me18S-G423 - http://flybase.org/reports/FBgn0086052 snoRNA_gene - - - "snoRNA:Me18S-G423, Me18S-Gm423, CR34681" - CR34681 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060297 p74S p74S http://flybase.org/reports/FBgn0060297 gene SH2 domain binding ; GO:0042169 | inferred from direct assay - - "p74, p74S" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025733 sca::Hsap\FGB sca::Hsap\FGB http://flybase.org/reports/FBgn0025733 - engineered_fusion_gene - - - sca::Hsap\FGB - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0004857 elA elbow A http://flybase.org/reports/FBgn0004857 FBgn0000569 gene - - - "el, elb, elA, el[A]" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable" "wing,posterior,wing vein L5,haltere,wing vein L4,alula,dorsal row,costal cell,wing vein L1" FBgn0260062 2L3547 - http://flybase.org/reports/FBgn0260062 gene - - - 2L3547 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0024752 Fs(2)1 Fs(2)1 http://flybase.org/reports/FBgn0024752 - gene - - - Fs(2)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,female sterile germline-dependent,dominant,viable" "egg,dorsal appendage,nurse cell,chorion" FBgn0042148 CG18825 - http://flybase.org/reports/FBgn0042148 protein_coding_gene - - - CG18825 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011635 l(2)T57h8 lethal (2) T57h8 http://flybase.org/reports/FBgn0011635 FBgn0005177 gene - - - l(2)T57h8 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033248 Dic3 Dicarboxylate carrier 3 http://flybase.org/reports/FBgn0033248 protein_coding_gene thiosulfate transmembrane transporter activity ; GO:0015117 | inferred from direct assay oxaloacetate transmembrane transporter activity ; GO:0015131 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transporter activity ; GO:0015140 | NOT inferred from direct assay succinate transmembrane transporter activity ; GO:0015141 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 inorganic phosphate transmembrane transporter activity ; GO:0005315 | inferred from direct assay antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 sulfate transmembrane transporter activity ; GO:0015116 | inferred from direct assay mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transport ; GO:0071423 | NOT inferred from direct assay thiosulfate transport ; GO:0015709 | inferred from direct assay oxaloacetate transport ; GO:0015729 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 phosphate ion transmembrane transport ; GO:0035435 | inferred from direct assay succinate transmembrane transport ; GO:0071422 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 sulfate transport ; GO:0008272 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 mitochondrion ; GO:0005739 | inferred from direct assay "CG11196, Dic3, Dic3p" "IPR002067:Mitochondrial carrier protein, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG11196 11-Aug-17 DroID_v2017_08 "Drer\mrpl12, Drer\si:ch1073-100f3.2, Drer\slc25a10, Drer\ucp2, Drer\slc25a14, Drer\slc25a11" Scer\DIC1 "Cele\ucp-4, Cele\slc-25A10, Cele\mrpl-12" "Xtro\rangrf, Xtro\ucp1, Xtro\slc25a30, Xtro\slc25a10, Xtro\ucp2, Xtro\slc25a27" "Mmus\Mrpl12, Mmus\Ucp2, Mmus\Slc25a27, Mmus\Ucp3, Mmus\Slc25a14, Mmus\Ucp1, Mmus\Slc25a30, Mmus\Slc25a10, Mmus\Slc25a11" "Hsap\UCP2, Hsap\SLC25A14, Hsap\UCP1, Hsap\UCP3, Hsap\SLC25A30, Hsap\MRPL12, Hsap\SLC25A10, Hsap\SLC25A11, Hsap\SLC25A27" "viable,body color defective" mesothoracic tergum FBgn0028012 l(3)S110013 lethal (3) S110013 http://flybase.org/reports/FBgn0028012 gene - - - "1100/13, l(3)S110013" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0032671 CG7200 - http://flybase.org/reports/FBgn0032671 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7200 IPR003347:JmjC domain CG7200 11-Aug-17 DroID_v2017_08 "Drer\jmjd8, Drer\jmjd4" - Cele\jmjd-4 "Xtro\jmjd4, Xtro\jmjd8" "Mmus\Jmjd4, Mmus\Jmjd8" "Hsap\JMJD4, Hsap\JMJD8" viable FBgn0259371 C125 - http://flybase.org/reports/FBgn0259371 gene - - - C125 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,supernumerary,wing" FBgn0011619 l(1)K49c-A7 lethal (1) K49c-A7 http://flybase.org/reports/FBgn0011619 - gene - - - l(1)K49c-A7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005479 l(1)ts1107 lethal (1) ts1107 http://flybase.org/reports/FBgn0005479 - gene - - - l(1)ts1107 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0023528 CG2924 - http://flybase.org/reports/FBgn0023528 - protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:19248 protein K48-linked ubiquitination ; GO:0070936 | inferred from sequence or structural similarity with HGNC:19248 cellular_component ; GO:0005575 | no biological data available "CG2924, EG:25E8.2, NICE5" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG2924 11-Aug-17 DroID_v2017_08 "Drer\ube2ql1, Drer\ube2q1, Drer\ube2q2" Scer\CDC34 Cele\ubc-25 "Xtro\ube2q2, Xtro\ube2ql1" "Mmus\Ube2ql1, Mmus\Ube2q2, Mmus\E330021D16Rik, Mmus\Ube2q1" "Hsap\UBE2Q2, Hsap\UBE2Q1, Hsap\UBE2QL1" FBgn0030963 CG7101 - http://flybase.org/reports/FBgn0030963 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG7101 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG7101 11-Aug-17 DroID_v2017_08 "Drer\zbtb48, Drer\LOC100330321, Drer\gtf3aa, Drer\LOC568955" Scer\PZF1 "Cele\ztf-29, Cele\pqm-1, Cele\F21A9.2, Cele\zag-1, Cele\F10B5.3" "Xtro\znf250, Xtro\zbtb48" Mmus\Gtf3a "Hsap\ZBTB26, Hsap\ZBTB48, Hsap\ZBTB6, Hsap\GTF3A" "viable,fertile" FBgn0001632 l(1)dn11 lethal (1) discs normal 11 http://flybase.org/reports/FBgn0001632 - gene - - - "l(1)d.norm.-11, l(1)dn11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0042143 CG18820 - http://flybase.org/reports/FBgn0042143 protein_coding_gene - - - CG18820 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035887 Jon66Cii Jonah 66Cii http://flybase.org/reports/FBgn0035887 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "66C, CG7170, SP165, Jon66C, Jon66Cii, CCG7170" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG7170 11-Aug-17 DroID_v2017_08 Drer\masp2 - - - "Mmus\C1s2, Mmus\Cela1, Mmus\C1s1" "Hsap\C1S, Hsap\F9, Hsap\PROC" viable FBgn0263037 CG43332 - http://flybase.org/reports/FBgn0263037 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43332, CG32972, BG:DS01523.2, CG15291" - CG43332 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037354 CG12171 - http://flybase.org/reports/FBgn0037354 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "anon-WO0118547.83, CG12171" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG12171 11-Aug-17 DroID_v2017_08 "Drer\decr2, Drer\elovl7a, Drer\elovl5, Drer\hsd17b14, Drer\pecr, Drer\dhrs7, Drer\hsd17b8, Drer\dhrs1, Drer\elovl4a, Drer\elovl8a, Drer\elovl4b, Drer\elovl7b, Drer\elovl1a, Drer\cbr4, Drer\decr1, Drer\elovl8b, Drer\hsdl2, Drer\elovl1b, Drer\zgc:101858, Drer\elovl2, Drer\bdh2, Drer\zgc:113054" "Scer\IRC24, Scer\OAR1, Scer\YIR035C, Scer\SPS19" "Cele\dhs-25, Cele\dhs-9, Cele\Y47G6A.22, Cele\F59E11.2, Cele\dhs-14, Cele\dhs-11, Cele\decr-1.2, Cele\C06E4.3, Cele\F26D2.15, Cele\ZK829.1, Cele\dhs-26, Cele\C33E10.10, Cele\F25D1.5, Cele\F12E12.11, Cele\F28H7.2, Cele\Y47G6A.21, Cele\D1054.8" "Xtro\MGC79752, Xtro\dhrs7, Xtro\elovl1, Xtro\dhrs4, Xtro\cbr4, Xtro\hsdl2, Xtro\elovl5, Xtro\hsd17b14, Xtro\elovl7, Xtro\hsd17b8, Xtro\decr1, Xtro\elovl2, Xtro\pecr, Xtro\MGC147226, Xtro\decr2" "Mmus\Elovl2, Mmus\Dhrs2, Mmus\Elovl7, Mmus\Hsdl2, Mmus\Bdh2, Mmus\Pecr, Mmus\Dhrs1, Mmus\Hsd17b14, Mmus\Elovl5, Mmus\Decr2, Mmus\H2-Ke6, Mmus\Decr1, Mmus\Dhrs7, Mmus\Cbr4, Mmus\Dhrs4, Mmus\Elovl4" "Hsap\DHRS4L2, Hsap\HSDL2, Hsap\ELOVL4, Hsap\ELOVL5, Hsap\PECR, Hsap\HSD17B8, Hsap\DECR2, Hsap\ELOVL7, Hsap\HSD17B14, Hsap\ELOVL2, Hsap\DECR1, Hsap\BDH2, Hsap\CBR4, Hsap\DHRS4, Hsap\DHRS1, Hsap\DHRS2, Hsap\ELOVL1, Hsap\DHRS7" "viable,fertile" FBgn0085232 CG34203 - http://flybase.org/reports/FBgn0085232 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34203 - CG34203 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000438 dfa deformed antennae http://flybase.org/reports/FBgn0000438 - gene - - - dfa - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile,male fertile,visible" "wing,eye,macrochaeta,antenna,arista,trident" FBgn0036623 CG4729 - http://flybase.org/reports/FBgn0036623 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR002123" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002123 endomembrane system ; GO:0012505 | inferred from direct assay "CG4729, AGPAT3" "IPR002123:Phospholipid/glycerol acyltransferase, IPR032098:Acyltransferase, C-terminal domain" CG4729 11-Aug-17 DroID_v2017_08 "Drer\lpgat1, Drer\agpat5, Drer\agpat4, Drer\lclat1, Drer\agpat3" "Scer\CST26, Scer\YDR018C" "Cele\bus-18, Cele\acl-11, Cele\acl-8, Cele\acl-9" "Xtro\lclat1, Xtro\agpat5, Xtro\lpgat1, Xtro\agpat4, Xtro\agpat3" "Mmus\Lpgat1, Mmus\Agpat5, Mmus\Agpat3, Mmus\Agpat4, Mmus\Lclat1" "Hsap\AGPAT3, Hsap\LPGAT1, Hsap\AGPAT4, Hsap\AGPAT5, Hsap\LCLAT1" "viable,fertile" FBgn0263479 scaRNA:PsiU2-35.45 small Cajal body-specific RNA : PsiU2-35.45 http://flybase.org/reports/FBgn0263479 snoRNA_gene snRNA pseudouridylation guide activity ; GO:0030565 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "scaRNA:PsiU2-35.45, pugU2-35/45, snoRNA:gp210-a" - CR43594 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004783 Ccp84Aa Ccp84Aa http://flybase.org/reports/FBgn0004783 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Ccp, cc8, CG2360, BG:DS00004.1, Ccp84Aa, DmelCcp84Aa" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2360 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable DRSC12586 K 0.13265466 -0.464154429 0.190789573 0.374079829 1.653664281 -0.886318367 FBgn0004230 l(3)93Bd lethal (3) 93Bd http://flybase.org/reports/FBgn0004230 - gene - - - "l(3)rlr2, rlr2, l(3)93Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013491 l(1)8PP9 lethal (1) 8PP9 http://flybase.org/reports/FBgn0013491 - gene - - - l(1)8PP9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect" "embryo,germline clone,embryonic/first instar larval cuticle" FBgn0065947 l(2)SH0100 lethal (2) SH0100 http://flybase.org/reports/FBgn0065947 gene - - - "l(2)SH0100, l(2)SH2 0100" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034058 Pex11 Peroxin 11 http://flybase.org/reports/FBgn0034058 protein_coding_gene - "regulation of peroxisome size ; GO:0044375 | inferred from biological aspect of ancestor with PANTHER:PTN000291586 peroxisome organization ; GO:0007031 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8852,HGNC:8853 peroxisome fission ; GO:0016559 | inferred from biological aspect of ancestor with PANTHER:PTN000291586" "integral component of peroxisomal membrane ; GO:0005779 | inferred from electronic annotation with InterPro:IPR008733 peroxisomal membrane ; GO:0005778 | inferred from biological aspect of ancestor with PANTHER:PTN000291586 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8852,HGNC:8853" "CG8315, Pex11, DmelPex11, PEX11A, PEX11B" IPR008733:Peroxisomal biogenesis factor 11 CG8315 11-Aug-17 DroID_v2017_08 "Drer\pex11g, Drer\pex11b, Drer\pex11a" Scer\PEX11 Cele\prx-11 "Xtro\pex11b, Xtro\pex11a, Xtro\pex11g" "Mmus\Itga10, Mmus\Pex11b, Mmus\Pex11a, Mmus\Pex11g" "Hsap\PEX11A, Hsap\PEX11G, Hsap\PEX11B" "viable,fertile" FBgn0034103 prim primacord http://flybase.org/reports/FBgn0034103 protein_coding_gene - detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype - "BcDNA:RH57845, prim, CG15704" - CG15704 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038596 CG14312 - http://flybase.org/reports/FBgn0038596 protein_coding_gene - - - CG14312 - CG14312 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259427 EP-149 - http://flybase.org/reports/FBgn0259427 gene - - - EP-149 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0065266 l(2)SH2068 lethal (2) SH2068 http://flybase.org/reports/FBgn0065266 gene - - - l(2)SH2068 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034850 CG9875 - http://flybase.org/reports/FBgn0034850 protein_coding_gene - - - "BcDNA:GH23338, CG9875" - CG9875 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005231 l(3)R18 lethal of Roberts 18 http://flybase.org/reports/FBgn0005231 - gene - - - "l(3)B18, l(3)R18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0035543 CG15020 - http://flybase.org/reports/FBgn0035543 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with dy cell morphogenesis ; GO:0000902 | inferred from sequence or structural similarity with dyl integral component of membrane ; GO:0016021 | inferred from sequence model CG15020 IPR001507:Zona pellucida domain CG15020 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001031, Drer\si:ch211-229d2.5, Drer\zgc:153932, Drer\si:ch211-103f14.3" - "Cele\cut-5, Cele\cutl-5, Cele\cutl-19, Cele\cutl-2, Cele\cutl-8, Cele\cutl-14, Cele\T01D1.8, Cele\cutl-18, Cele\cutl-11, Cele\cutl-24, Cele\F46G11.6, Cele\cutl-9, Cele\cutl-28, Cele\cut-1, Cele\cutl-29, Cele\cutl-15, Cele\cut-4, Cele\cutl-1, Cele\cutl-22, Cele\cutl-16, Cele\cutl-25, Cele\ram-5, Cele\cutl-4, Cele\cutl-13, Cele\cutl-3, Cele\cutl-12, Cele\cutl-7, Cele\cutl-20, Cele\cut-3, Cele\cutl-6, Cele\dpy-1, Cele\cut-6, Cele\cutl-10, Cele\cutl-26" "Xtro\thdl18, Xtro\MGC89178, Xtro\thdl17" - - "viable,fertile" FBgn0265695 CR44502 - http://flybase.org/reports/FBgn0265695 non_protein_coding_gene - - - CR44502 - CR44502 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260743 GC1 Glutamate Carrier 1 http://flybase.org/reports/FBgn0260743 protein_coding_gene high-affinity glutamate transmembrane transporter activity ; GO:0005314 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 L-glutamate transport ; GO:0015813 | inferred from mutant phenotype mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640304 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with MGI:MGI:1919053 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG18347, 87A7-9/4, anon-87Ac, DmGC1, GC1" "IPR018108:Mitochondrial substrate/solute carrier, IPR002067:Mitochondrial carrier protein, IPR023395:Mitochondrial carrier domain" CG18347 11-Aug-17 DroID_v2017_08 "Drer\slc25a22, Drer\si:ch73-219d10.1, Drer\slc25a12, Drer\slc25a18, Drer\si:dkey-201c1.2, Drer\zgc:92113" "Scer\GGC1, Scer\AGC1" "Cele\F55G1.5, Cele\F20D1.9, Cele\K02F3.2" "Xtro\slc25a22, Xtro\slc25a13, Xtro\slc25a18, Xtro\slc25a12" "Mmus\Slc25a12, Mmus\Slc25a18, Mmus\Slc25a22, Mmus\Slc25a13" "Hsap\SLC25A13, Hsap\SLC25A12, Hsap\SLC25A18, Hsap\SLC25A22" FBgn0004944 agq atrophie gonadique http://flybase.org/reports/FBgn0004944 - gene - - - agq - - 11-Aug-17 DroID_v2017_08 - - - - - - "grandchildless,heat sensitive" "pole cell,heat sensitive,gonad" FBgn0062560 P42 P42 http://flybase.org/reports/FBgn0062560 gene - - - P42 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262362 CG43060 - http://flybase.org/reports/FBgn0262362 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43060 - CG43060 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010770 ppan peter pan http://flybase.org/reports/FBgn0010770 "FBgn0011392, FBgn0026381" protein_coding_gene rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000292112 imaginal disc development ; GO:0007444 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype larval development ; GO:0002164 | inferred from mutant phenotype female gamete generation ; GO:0007292 | inferred from mutant phenotype ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000292112 "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000292112" "l(3)02231, l(3)j6B6, CG5786, ppan, Ppan, PPAN" IPR007109:Brix domain CG5786 11-Aug-17 DroID_v2017_08 "Drer\p2ry11, Drer\ppan" "Scer\SSF2, Scer\SSF1" Cele\lpd-6 Xtro\ppan Mmus\Ppan "Hsap\PPAN-P2RY11, Hsap\PPAN, Hsap\P2RY11" " embryonic stage , adult stage && oogenesis stage "

ubiquitous "lethal,polyphasic,recessive,wild-type,visible,increased cell death,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,adult cuticle,wing margin bristle,egg,nurse cell,oocyte,wing,wing vein,posterior,wing disc,dorsal,wing hair & wing | dorsalBx-MS1096,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC17030 E 0.012365267 0.429085793 -2.129446907 -0.065422564 -0.421742788 -0.527329521 FBgn0035332 CG13801 - http://flybase.org/reports/FBgn0035332 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004680 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004680 CG13801 IPR004680:Citrate transporter-like domain CG13801 11-Aug-17 DroID_v2017_08 Drer\oca2 - Cele\srh-98 Xtro\oca2 Mmus\Oca2 Hsap\OCA2 FBgn0030850 stas Stasimon http://flybase.org/reports/FBgn0030850 protein_coding_gene - "positive regulation of synaptic transmission, cholinergic ; GO:0032224 | inferred from mutant phenotype" - "CG8408, stas, Tmem41b" "IPR032816:SNARE associated Golgi protein, IPR015943:WD40/YVTN repeat-like-containing domain" CG8408 11-Aug-17 DroID_v2017_08 "Drer\tmem41b, Drer\tmem41aa, Drer\tmem41ab, Drer\tmem64" Scer\TVP38 "Cele\tag-175, Cele\bus-19, Cele\Y71A12C.2" Xtro\tmem41b "Mmus\Tmem41a, Mmus\Tmem64, Mmus\Tmem41b" "Hsap\TMEM64, Hsap\TMEM41A, Hsap\TMEM41B" "viable,neurophysiology defective" "embryonic/larval neuromuscular junction | larval stage,embryonic/larval neuromuscular junction" FBgn0022221 l(2)k03303 lethal (2) k03303 http://flybase.org/reports/FBgn0022221 - gene - - - l(2)k03303 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260092 2L2769 - http://flybase.org/reports/FBgn0260092 gene - - - 2L2769 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0267582 CR45922 - http://flybase.org/reports/FBgn0267582 non_protein_coding_gene - - - CR45922 - CR45922 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037801 CG3999 - http://flybase.org/reports/FBgn0037801 protein_coding_gene "glycine dehydrogenase (decarboxylating) activity ; GO:0004375 | inferred from electronic annotation with InterPro:IPR003437, InterPro:IPR020581" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003437, InterPro:IPR020580, InterPro:IPR020581 glycine catabolic process ; GO:0006546 | inferred from electronic annotation with InterPro:IPR020580, InterPro:IPR020581" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000206533 CG3999 "IPR003437:Glycine dehydrogenase (decarboxylating), IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR020581:Glycine cleavage system P protein, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG3999 11-Aug-17 DroID_v2017_08 Drer\gldc Scer\GCV2 Cele\R12C12.1 Xtro\gldc Mmus\Gldc Hsap\GLDC partially lethal - majority die FBgn0003439 smaller-eye smaller eye http://flybase.org/reports/FBgn0003439 - gene - - - "smaller-eye, sme" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable,male,reduced,visible,eye color defective" "pigment cell,eye,wing" FBgn0037426 CG18394 - http://flybase.org/reports/FBgn0037426 protein_coding_gene - - - CG18394 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026339 Su(tor)2-28-23 Su(tor)2-28-23 http://flybase.org/reports/FBgn0026339 - gene - - - Su(tor)2-28-23 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020593 anon-57Cd anon-57Cd http://flybase.org/reports/FBgn0020593 - gene - - - anon-57Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050339 CG30339 - http://flybase.org/reports/FBgn0050339 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "BcDNA:RE54230, CG30339" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG30339 11-Aug-17 DroID_v2017_08 "Drer\rlbp1b, Drer\rlbp1a, Drer\sec14l8, Drer\sec14l7, Drer\clvs2, Drer\ttpal, Drer\ttpa" "Scer\SFH5, Scer\YKL091C, Scer\SEC14" - "Xtro\sec14l3, Xtro\ttpal, Xtro\sec14l5, Xtro\clvs1, Xtro\rlbp1, Xtro\mospd2, Xtro\clvs2, Xtro\ttpa, Xtro\sec14l1" "Mmus\Ttpal, Mmus\Clvs2, Mmus\Sec14l5, Mmus\Sec14l2, Mmus\Rlbp1, Mmus\Ttpa, Mmus\Clvs1, Mmus\Sec14l1, Mmus\Sec14l4, Mmus\Sec14l3" "Hsap\CLVS1, Hsap\SEC14L1, Hsap\CLVS2, Hsap\SEC14L5, Hsap\SEC14L4, Hsap\SEC14L6, Hsap\RLBP1, Hsap\SEC14L3, Hsap\SEC14L2, Hsap\TTPA, Hsap\TTPAL" FBgn0004747 l(3)85Fd lethal (3) 85Fd http://flybase.org/reports/FBgn0004747 - gene - - - l(3)85Fd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014105 anon-4Cd anon-4Cd http://flybase.org/reports/FBgn0014105 - gene - - - "T8a,b, anon-4Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001668 l(1)EN4 lethal (1) from Eugene Nonautonomous 4 http://flybase.org/reports/FBgn0001668 - gene - - - l(1)EN4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084170 Abd-B-PTS6 Abdominal B promoter targeting sequence 6 http://flybase.org/reports/FBgn0084170 regulatory_region - - - "PTS-6, Abd-B-PTS6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0278603 Scr::Mmus\Hoxa5 - http://flybase.org/reports/FBgn0278603 engineered_fusion_gene - - - Scr::Mmus\Hoxa5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003404 Si Ski http://flybase.org/reports/FBgn0003404 - gene - - - Si - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0021914 l(2)k11405 lethal (2) k11405 http://flybase.net/reports/FBgn0021914.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0035704 Vps8 Vacuolar protein sorting 8 http://flybase.org/reports/FBgn0035704 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model GTPase binding ; GO:0051020 | inferred from sequence or structural similarity with SGD:S000000002 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR000547 vesicle-mediated transport ; GO:0016192 | inferred from electronic annotation with InterPro:IPR000547 endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000000002 CORVET complex ; GO:0033263 | inferred from sequence or structural similarity with SGD:S000000002 "anon-WO0118547.365, CG10144, Vps8" "IPR025941:Vacuolar protein sorting-associated protein 8, central domain, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR001841:Zinc finger, RING-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000547:Clathrin, heavy chain/VPS, 7-fold repeat, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10144 11-Aug-17 DroID_v2017_08 Drer\vps8 Scer\VPS8 Cele\C42C1.4 Xtro\vps8 Mmus\Vps8 Hsap\VPS8 viable FBgn0262018 CadN2 Cadherin-N2 http://flybase.org/reports/FBgn0262018 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR001881, InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model receptor activity ; GO:0004872 | inferred from sequence or structural similarity cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity" "homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR002126 cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model R8 cell development ; GO:0045463 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from sequence or structural similarity calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity axon extension involved in axon guidance ; GO:0048846 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR020894 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "CadN2, cadN2, N-Cad2, NCad2, DmNCad2, CG7527, CT23007, DN-like, DN-Cad2, DNcad2, DN-cad2, CG42829, Ncad2" "IPR000233:Cadherin, cytoplasmic domain, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR001881:EGF-like calcium-binding domain, IPR002126:Cadherin, IPR013032:EGF-like, conserved site, IPR015919:Cadherin-like, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR027397:Catenin binding domain, IPR020894:Cadherin conserved site" CG42829 11-Aug-17 DroID_v2017_08 "Drer\pcdh15b, Drer\cdh6, Drer\fat3a, Drer\si:ch211-186j3.6, Drer\pcdh1g30, Drer\pcdh2ab8, Drer\cdh5, Drer\pcdh15a, Drer\pcdh2g1, Drer\pcdh2g8, Drer\pcdh2ab6, Drer\dsc2l, Drer\cdh17, Drer\pcdh1g33, Drer\dchs1a, Drer\pcdh2ab2, Drer\cdh15, Drer\LOC567936, Drer\pcdh2ab11, Drer\fat1b, Drer\pcdh2ab7, Drer\cdh19, Drer\LOC100006797, Drer\fat1a, Drer\cdh26.1, Drer\pcdh1a6, Drer\pcdh2ab9, Drer\cdh8, Drer\cdh10a, Drer\pcdh1gb2, Drer\cdh23, Drer\si:dkey-22o22.2, Drer\pcdh2ab10, Drer\cdh13, Drer\pcdh1g22, Drer\cdh31, Drer\cdh2, Drer\LOC100536351, Drer\dchs1b, Drer\pcdh2ab5, Drer\cdh16, Drer\cdh12a, Drer\pcdh2ab3, Drer\si:dkey-30c15.10, Drer\cdh27, Drer\fat2, Drer\pcdh10a, Drer\cdh1, Drer\cdh4, Drer\pcdh2ab1, Drer\pcdh2aa15, Drer\cdh11, Drer\si:busm1-71b9.3, Drer\cdh7, Drer\pcdh2g3, Drer\LOC100329245, Drer\pcdh1gc5, Drer\pcdh10b, Drer\LOC103909937, Drer\pcdh1g18" - "Cele\cdh-12, Cele\hmr-1, Cele\akir-1, Cele\cdh-7" "Xtro\dchs2, Xtro\fat4, Xtro\fat1" "Mmus\Pcdhb9, Mmus\Pcdh10, Mmus\Cdh12, Mmus\Cdh17, Mmus\Cdh3, Mmus\Cdh24, Mmus\Fat1, Mmus\Pcdhac2, Mmus\Cdh10, Mmus\Dsc3, Mmus\Pcdhb17, Mmus\Cdh8, Mmus\Cdh2, Mmus\Pcdhb7, Mmus\Pcdhb4, Mmus\Cdh16, Mmus\Cdh6, Mmus\Cdh18, Mmus\Dsg2, Mmus\Dchs1, Mmus\Cdh7, Mmus\Pcdhb2, Mmus\Cdhr3, Mmus\Cdh26, Mmus\Pcdhb13, Mmus\Pcdh18, Mmus\Pcdh1, Mmus\Cdh1, Mmus\Fat3, Mmus\Pcdhb8, Mmus\Cdh4, Mmus\Pcdhb15, Mmus\Dsc1, Mmus\Cdh9, Mmus\Cdh13, Mmus\Pcdhb14, Mmus\Cdh22, Mmus\Pcdhb5, Mmus\Cdh15, Mmus\Cdh5, Mmus\Pcdhb16, Mmus\Pcdhb12, Mmus\Cdh20, Mmus\Dsg3, Mmus\Cdh23, Mmus\Dsc2, Mmus\Cdh11, Mmus\Fat2, Mmus\Pcdh17, Mmus\Cdh19, Mmus\Pcdhgc5" "Hsap\CDH10, Hsap\PCDHGB5, Hsap\PCDHGA10, Hsap\PCDHB2, Hsap\PCDHB4, Hsap\CDH12, Hsap\CDH15, Hsap\CDH7, Hsap\PCDHGA4, Hsap\CDH11, Hsap\PCDHA11, Hsap\CDHR3, Hsap\CDH22, Hsap\PCDHA1, Hsap\PCDH10, Hsap\CDH26, Hsap\PCDH18, Hsap\CDH9, Hsap\DSC3, Hsap\AKIRIN2, Hsap\CDH18, Hsap\PCDHB7, Hsap\CDH6, Hsap\CDH8, Hsap\PCDH1, Hsap\PCDHB6, Hsap\PCDHB8, Hsap\PCDH9, Hsap\PCDH17, Hsap\DLK2, Hsap\PCDHGC4, Hsap\AKIRIN1, Hsap\PCDHB13, Hsap\CDH23, Hsap\DSG2, Hsap\CDH4, Hsap\CDH17, Hsap\DSG4, Hsap\CDH5, Hsap\FAT2, Hsap\PCDHGB7, Hsap\CDH19, Hsap\DSG3, Hsap\FAT1, Hsap\PCDHGB1, Hsap\PCDHA3, Hsap\CDH20, Hsap\DSC2, Hsap\PCDHGA2, Hsap\PCDHA2, Hsap\CDH3, Hsap\DSC1, Hsap\CDH1, Hsap\CDH2, Hsap\DCHS1, Hsap\PCDHGC5, Hsap\PCDHGB4, Hsap\DCHS2, Hsap\FAT3, Hsap\PCDHGA12, Hsap\PCDHGA3, Hsap\PCDHA5, Hsap\CDH24, Hsap\FAT4, Hsap\CDH13" "viable,partially lethal - majority die,some die during pupal stage" FBgn0065135 l(3)SH118 lethal (3) SH118 http://flybase.org/reports/FBgn0065135 gene - - - "l(3)SH118, l(2)SH3 118" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065623 l(2)SH0799 lethal (2) SH0799 http://flybase.org/reports/FBgn0065623 gene - - - "l(2)SH0799, l(2)SH2 0799" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038961 CG13850 - http://flybase.org/reports/FBgn0038961 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR010622 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:24676 - "GH07286p, CG13850" "IPR010622:FAST kinase leucine-rich, IPR013579:FAST kinase-like protein, subdomain 2, IPR013584:RAP domain" CG13850 11-Aug-17 DroID_v2017_08 "Drer\fastk, Drer\fastkd1, Drer\tbrg4, Drer\fastkd3, Drer\fastkd5, Drer\fastkd2" - "Cele\fbxa-46, Cele\C52E2.5, Cele\B0564.7" "Xtro\fastkd3, Xtro\fastkd5, Xtro\fastkd1, Xtro\tbrg4" "Mmus\Fastkd5, Mmus\Tbrg4, Mmus\Fastk, Mmus\Fastkd2, Mmus\Fastkd1, Mmus\Fastkd3" "Hsap\FASTKD5, Hsap\FASTK, Hsap\FASTKD1, Hsap\TBRG4, Hsap\FASTKD3, Hsap\FASTKD2" viable FBgn0022086 l(2)k07408 lethal (2) k07408 http://flybase.org/reports/FBgn0022086 - gene - - - "l(2)K07408, l(2)k07408" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265050 CR44165 - http://flybase.org/reports/FBgn0265050 non_protein_coding_gene - - - CR44165 - CR44165 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043474 micropia\pol micropia element pol http://flybase.org/reports/FBgn0043474 transposable_element_gene - - - micropia\pol - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266959 CR45410 - http://flybase.org/reports/FBgn0266959 non_protein_coding_gene - - - CR45410 - CR45410 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033893 CG18371 - http://flybase.org/reports/FBgn0033893 protein_coding_gene acylphosphatase activity ; GO:0003998 | inferred from biological aspect of ancestor with PANTHER:PTN000003030 - - CG18371 "IPR001792:Acylphosphatase-like domain, IPR017968:Acylphosphatase, conserved site, IPR020456:Acylphosphatase" CG18371 11-Aug-17 DroID_v2017_08 "Drer\acyp2, Drer\acyp1" - - "Xtro\acyp2, Xtro\acyp1" "Mmus\Acyp2, Mmus\Acyp1" "Hsap\ACYP1, Hsap\ACYP2" viable FBgn0010025 E(Dl)F10 Enhancer of Delta F10 http://flybase.org/reports/FBgn0010025 - gene - - - E(Dl)F10 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022029 l(2)k01209 lethal (2) k01209 http://flybase.org/reports/FBgn0022029 "FBgn0022251, FBgn0034213" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006083 uridine kinase activity ; GO:0004849 | inferred from sequence or structural similarity with SGD:S000005295 uridine kinase activity ; GO:0004849 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine nucleoside salvage ; GO:0043097 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine-containing compound salvage ; GO:0008655 | inferred from sequence or structural similarity with SGD:S000005295 pyrimidine nucleobase metabolic process ; GO:0006206 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005295 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005295 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 "CG4798, l(2)k08901, l(2)k01209, l(2)K01209" "IPR000764:Uridine kinase-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR029057:Phosphoribosyltransferase-like, IPR006083:Phosphoribulokinase/uridine kinase, IPR000836:Phosphoribosyltransferase domain" CG4798 11-Aug-17 DroID_v2017_08 "Drer\jupa, Drer\ctnnb2, Drer\uckl1a, Drer\uprt, Drer\jupb, Drer\uck1, Drer\si:ch211-243j20.2, Drer\uck2b, Drer\uck2a, Drer\uckl1b, Drer\ctnnb1" "Scer\FUR1, Scer\NRK1, Scer\URK1" "Cele\C47B2.2, Cele\F19B6.1" "Xtro\ctnnb1, Xtro\jup, Xtro\uck1, Xtro\uck2, Xtro\uckl1, Xtro\uprt" "Mmus\Uck1, Mmus\Jup, Mmus\Uckl1, Mmus\Ctnnb1, Mmus\Uprt, Mmus\Uck2" "Hsap\UCKL1, Hsap\UCK1, Hsap\UPRT, Hsap\JUP, Hsap\UCK2, Hsap\CTNNB1" "lethal,recessive,viable,fertile" FBgn0263883 l(3)G34 - http://flybase.org/reports/FBgn0263883 gene - - - l(3)G34 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,mitotic cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0053220 CG33220 - http://flybase.org/reports/FBgn0053220 protein_coding_gene - - - CG33220 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024582 l(3)rO220 lethal (3) rO220 http://flybase.org/reports/FBgn0024582 - gene - - - l(3)rO220 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033828 CG17048 - http://flybase.org/reports/FBgn0033828 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17048 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17048 11-Aug-17 DroID_v2017_08 - - "Cele\T02C1.1, Cele\K09F6.7, Cele\nhl-1, Cele\T24D1.3" - Mmus\Bfar Hsap\BFAR viable FBgn0262421 mir-13b-2 mir-13b-2 stem loop http://flybase.org/reports/FBgn0262421 miRNA_gene - - - "miR-13b-2, mir-13b, mir-13b-2, dme-mir-13b-2, Dme-miR-13b, 13b-1/2, CR42972, miR-13b, miR-13, CR33079, miR-13B, miR-13-b2, dme-mir-13b, dme-miR-13b, dme-miR-13b-2" - CR42972 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage viable FBgn0085337 CG34308 - http://flybase.org/reports/FBgn0085337 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-like protein conjugating enzyme binding ; GO:0044390 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 Derlin-1 retrotranslocation complex ; GO:0036513 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 CG34308 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR017907:Zinc finger, RING-type, conserved site" CG34308 11-Aug-17 DroID_v2017_08 "Drer\rnf185, Drer\rnf5, Drer\timeless" Scer\TOF1 Cele\rnf-5 Xtro\timeless "Mmus\Rnf185, Mmus\Rnf5, Mmus\Timeless" "Hsap\TIMELESS, Hsap\RNF5, Hsap\RNF185" FBgn0250850 rig rigor mortis http://flybase.org/reports/FBgn0250850 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P16375 inferred from physical interaction with UniProtKB:P20153 inferred from physical interaction with UniProtKB:P31396 inferred from physical interaction with UniProtKB:P34021 inferred from physical interaction with UniProtKB:Q05192 "molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype response to ecdysone ; GO:0035075 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype spliceosomal snRNP assembly ; GO:0000387 | inferred from sequence or structural similarity with UniProtKB:Q8TEQ6" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay SMN complex ; GO:0032797 | inferred from genetic interaction with Gem3 "Rig, CG30149, l(2)05056, CG13440, CG11171, rig, anon-SAGE:Wang-132, Gem5" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG30149 11-Aug-17 DroID_v2017_08 "Drer\grwd1, Drer\gemin5" "Scer\RRB1, Scer\WTM1, Scer\WTM2, Scer\UME1" Cele\Y54H5A.1 Xtro\gemin5 "Mmus\Gemin5, Mmus\Grwd1" "Hsap\GEMIN5, Hsap\GRWD1" FBgn0259402 EP-501 - http://flybase.org/reports/FBgn0259402 gene - - - EP-501 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0066359 l(2)199 lethal (2) 199 http://flybase.org/reports/FBgn0066359 gene - - - l(2)199 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0047351 CG31468 - http://flybase.org/reports/FBgn0047351 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs18e02, NEST:bs21c04, NEST:bs34b06, NEST:bs12h04, BcDNA:AT08725, CG31468, Tes37" IPR010736:Sperm-tail PG-rich repeat CG31468 11-Aug-17 DroID_v2017_08 "Drer\odf3l2, Drer\zgc:110183" - - - "Mmus\Odf3l1, Mmus\Odf3l2" "Hsap\ODF3L2, Hsap\ODF3L1" viable FBgn0041233 Gr59e Gustatory receptor 59e http://flybase.org/reports/FBgn0041233 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr59E2, CG15872, 59E2, 59E.2, GR59E.2, CG33151, Gr59e, GR59e, Gr59E" IPR013604:7TM chemoreceptor CG33151 11-Aug-17 DroID_v2017_08 "Drer\asic1a, Drer\asic1c, Drer\asic4a, Drer\asic4b, Drer\asic1b, Drer\asic2" - "Cele\srt-26, Cele\srt-30, Cele\srt-53, Cele\srt-27, Cele\srt-28" "Xtro\scnn1d, Xtro\scnn1a, Xtro\asic4, Xtro\scnn1g, Xtro\asic1, Xtro\asic5, Xtro\scnn1b" "Mmus\Scnn1b, Mmus\Asic5, Mmus\Scnn1a, Mmus\Asic4, Mmus\Scnn1g, Mmus\Asic3, Mmus\Asic2, Mmus\Asic1" "Hsap\ASIC5, Hsap\ASIC2, Hsap\SCNN1G, Hsap\ASIC4, Hsap\ASIC1, Hsap\ASIC3, Hsap\SCNN1A, Hsap\SCNN1B, Hsap\SCNN1D" viable FBgn0022109 l(2)k07001 lethal (2) k07001 http://flybase.org/reports/FBgn0022109 - gene - - - l(2)k07001 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086296 bleb bleb http://flybase.org/reports/FBgn0086296 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - bleb - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0044061 GTD74-198 GTD74-198 http://flybase.org/reports/FBgn0044061 gene - - - GTD74-198 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023054 l(1)3ABb lethal (1) 3ABb http://flybase.org/reports/FBgn0023054 - gene - - - "1200C6, l(1)3ABb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266343 so::Optix - http://flybase.org/reports/FBgn0266343 engineered_fusion_gene - - - so::Optix - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,ectopic" FBgn0283501 CR46115 - http://flybase.org/reports/FBgn0283501 non_protein_coding_gene - - - "CR46115, CR45992" - CR46115 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037275 CG14655 - http://flybase.org/reports/FBgn0037275 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG14655 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG14655 11-Aug-17 DroID_v2017_08 "Drer\znf281a, Drer\bcl6b, Drer\LOC100537687, Drer\bcl6a, Drer\prdm13, Drer\bcl6ab" "Scer\YPR015C, Scer\CMR3" "Cele\zag-1, Cele\ztf-30, Cele\ztf-16, Cele\Y55F3AM.14" "Xtro\znf142, Xtro\bcl6" "Mmus\Bcl6, Mmus\Ikzf5, Mmus\Prdm13, Mmus\Bcl6b" "Hsap\BCL6B, Hsap\BCL6, Hsap\PRDM13, Hsap\ZBTB16, Hsap\ZNF81, Hsap\TIGD1, Hsap\IKZF5" viable FBgn0040091 Ugt58Fa Ugt58Fa http://flybase.org/reports/FBgn0040091 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG4414, AC 004377A, Ugt58Fa, ugt58Fa" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG4414 11-Aug-17 DroID_v2017_08 "Drer\ugt2a6, Drer\ugt1b4, Drer\ugt5f1, Drer\ugt5g1, Drer\ugt2b6, Drer\ugt8, Drer\ugt1b2, Drer\ugt5c3, Drer\zgc:172315, Drer\ugt5b1, Drer\ugt5a1, Drer\ugt2b1, Drer\ugt5e1, Drer\ugt1b7, Drer\ugt1b3, Drer\ugt2a5, Drer\ugt5g2, Drer\ugt5b3, Drer\ugt1ab, Drer\ugt2b5, Drer\ugt2b3, Drer\ugt5b6, Drer\ugt5a4, Drer\ugt5b2, Drer\ugt5c1, Drer\ugt5c2, Drer\ugt5d1, Drer\ugt2a2, Drer\ugt5a5, Drer\ugt1b5, Drer\ugt5a2" Scer\ATG26 "Cele\ugt-25, Cele\ugt-3, Cele\ugt-30, Cele\ugt-28, Cele\ugt-6, Cele\ugt-9, Cele\ugt-1, Cele\ugt-46, Cele\C55H1.1, Cele\F10D2.8, Cele\ugt-11, Cele\ugt-36, Cele\ugt-5, Cele\ugt-14, Cele\ugt-22, Cele\ugt-47, Cele\ugt-29, Cele\ugt-40, Cele\ugt-55, Cele\ugt-49, Cele\ugt-60, Cele\ugt-2, Cele\H23N18.4, Cele\ugt-27, Cele\ugt-56, Cele\ugt-23, Cele\ugt-13, Cele\ugt-8, Cele\ugt-33, Cele\C03A7.13, Cele\K04A8.10, Cele\ugt-51, Cele\ugt-44, Cele\ugt-37, Cele\ugt-35, Cele\ugt-52, Cele\ugt-32, Cele\ugt-18, Cele\ugt-54, Cele\ugt-34, Cele\Y43D4A.2, Cele\ugt-24, Cele\ugt-43, Cele\ugt-15, Cele\ugt-17, Cele\C03A7.12, Cele\ugt-31, Cele\ugt-39, Cele\ugt-50, Cele\ugt-10, Cele\ugt-12, Cele\ugt-59, Cele\ugt-38, Cele\C23G10.6, Cele\ugt-19, Cele\ugt-16, Cele\ugt-4, Cele\ugt-48, Cele\ugt-53, Cele\ugt-58, Cele\ugt-7, Cele\ugt-41, Cele\ugt-45, Cele\ugt-61, Cele\ugt-21, Cele\ugt-20, Cele\ugt-42, Cele\ugt-26, Cele\ugt-62" "Xtro\ugt1a6, Xtro\ugt8, Xtro\ugt3a2, Xtro\ugt2b4, Xtro\ugt2a1" "Mmus\Ugt2b34, Mmus\Ugt8a, Mmus\Ugt2b36, Mmus\Ugt2b37, Mmus\Ugt3a1, Mmus\Ugt2b35, Mmus\Ugt2b1, Mmus\Ugt2b38, Mmus\Ugt1a9, Mmus\Ugt2a1, Mmus\Ugt1a2, Mmus\Ugt1a7c, Mmus\Ugt1a6b, Mmus\Ugt2b5, Mmus\Ugt1a5, Mmus\Ugt1a1, Mmus\Ugt3a2, Mmus\Ugt2a3" "Hsap\UGT3A2, Hsap\UGT1A7, Hsap\UGT2A3, Hsap\UGT2B15, Hsap\UGT2B4, Hsap\UGT1A9, Hsap\UGT2B11, Hsap\UGT8, Hsap\UGT2B10, Hsap\UGT1A6, Hsap\UGT1A1, Hsap\UGT2B17, Hsap\UGT1A5, Hsap\UGT1A10, Hsap\UGT1A4, Hsap\UGT3A1, Hsap\UGT1A3, Hsap\UGT2B7, Hsap\UGT1A8, Hsap\UGT2B28, Hsap\UGT2A2" viable DRSC04470 K 0.182574293 0.710379522 0.472020452 0.037192778 0.4394413 -1.689647062 FBgn0025163 l(2)38Eb lethal (2) 38Eb http://flybase.org/reports/FBgn0025163 - gene - - - l(2)38Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031614 CG11934 - http://flybase.org/reports/FBgn0031614 protein_coding_gene - - - CG11934 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037851 CG4664 - http://flybase.org/reports/FBgn0037851 protein_coding_gene - - - CG4664 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002003 l(2)36Bb lethal (2) 36Bb http://flybase.org/reports/FBgn0002003 - gene - - - "l(2L)HT-7, l(2)HT-7, l(2)36Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0023162 Su(mg)1-6 Suppressor of modifier of gypsy 1-6 http://flybase.org/reports/FBgn0023162 - gene - - - Su(mg)1-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065532 l(2)SH1106 lethal (2) SH1106 http://flybase.org/reports/FBgn0065532 gene - - - "l(2)SH1106, l(2)SH2 1106" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037137 Nopp140 Nopp140 http://flybase.org/reports/FBgn0037137 protein_coding_gene - ribosome biogenesis ; GO:0042254 | inferred from mutant phenotype rRNA 2'-O-methylation ; GO:0000451 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay "CG7421, DmNopp140, Nopp140, nopp140, Nopp- 140" "IPR007718:SRP40, C-terminal, IPR017859:Treacle-like, Treacher Collins Syndrome" CG7421 11-Aug-17 DroID_v2017_08 Drer\nolc1 "Scer\SRP40, Scer\NSP1" "Cele\dao-5, Cele\cec-8" Xtro\nolc1 Mmus\Nolc1 Hsap\NOLC1 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0265988 mv mauve http://flybase.org/reports/FBgn0265988 protein_coding_gene - negative regulation of autophagosome size ; GO:0045771 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000348578 "CG42863, mv, CG11814, CG5691" "IPR011993:PH domain-like, IPR023362:PH-BEACH domain, IPR000409:BEACH domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG42863 11-Aug-17 DroID_v2017_08 "Drer\nbeaa, Drer\nsmaf, Drer\lrba, Drer\nbeal2, Drer\wdfy4, Drer\wdr81, Drer\wdfy3, Drer\nbeab" Scer\BPH1 Cele\lyst-1 "Xtro\wdfy3, Xtro\nsmaf, Xtro\lyst" "Mmus\Nbeal2, Mmus\Nsmaf, Mmus\Wdr81, Mmus\Nbea, Mmus\Wdfy3, Mmus\Lyst, Mmus\Lrba, Mmus\Wdfy4" "Hsap\NBEAL2, Hsap\NSMAF, Hsap\NBEA, Hsap\WDR81, Hsap\LYST, Hsap\WDFY3, Hsap\LRBA, Hsap\WDFY4" FBgn0250840 CG12907 - http://flybase.org/reports/FBgn0250840 protein_coding_gene - - - "CG12907, BcDNA:AT31822, anon-WO0140519.79, anon-SAGE:Wang-109" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034497 CG9090 - http://flybase.org/reports/FBgn0034497 protein_coding_gene phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from biological aspect of ancestor with PANTHER:PTN000639943 phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from sequence or structural similarity with UniProtKB:Q00325 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 phosphate ion transport ; GO:0006817 | inferred from sequence or structural similarity with UniProtKB:Q00325 mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity with UniProtKB:Q00325 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 CG9090 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG9090 11-Aug-17 DroID_v2017_08 "Drer\slc25a3a, Drer\slc25a3b" "Scer\PIC2, Scer\MIR1" "Cele\F01G4.6, Cele\C33F10.12, Cele\C14C10.1, Cele\T05F1.8" Xtro\slc25a3 Mmus\Slc25a3 Hsap\SLC25A3 viable FBgn0002016 l(2)36Fi lethal (2) 36Fi http://flybase.org/reports/FBgn0002016 - gene - - - "l(2)E105, l(2)36Fi" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267028 CR45472 - http://flybase.org/reports/FBgn0267028 non_protein_coding_gene - - - "CR45472, CR43790, CR43CR43790786, CR43791" - CR45472 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029728 CG2861 - http://flybase.org/reports/FBgn0029728 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2861 - CG2861 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259382 EP-329 - http://flybase.org/reports/FBgn0259382 gene - - - EP-329 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0083995 CG41353 - http://flybase.org/reports/FBgn0083995 protein_coding_gene - - - CG41353 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000109 Aprt Adenine phosphoribosyltransferase http://flybase.org/reports/FBgn0000109 "FBgn0035288, FBgn0063099" protein_coding_gene adenine phosphoribosyltransferase activity ; GO:0003999 | inferred from electronic annotation with InterPro:IPR005764 adenine salvage ; GO:0006168 | inferred from electronic annotation with InterPro:IPR005764 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000836 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR005764 "aprt, CG18315, BcDNA:LP07986, Aprt" "IPR000836:Phosphoribosyltransferase domain, IPR005764:Adenine phosphoribosyl transferase, IPR029057:Phosphoribosyltransferase-like" CG18315 11-Aug-17 DroID_v2017_08 "Drer\zgc:174895, Drer\aprt" "Scer\APT2, Scer\APT1" Cele\T19B4.3 "Xtro\aprt, Xtro\LOC100145149" Mmus\Aprt Hsap\APRT "chemical resistant,long lived,electrophoretic variant,fast,slow,viable" FBgn0032772 CG17350 - http://flybase.org/reports/FBgn0032772 protein_coding_gene - - - CG17350 - CG17350 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0030305 Uba5 Ubiquitin activating enzyme 5 http://flybase.org/reports/FBgn0030305 protein_coding_gene UFM1 activating enzyme activity ; GO:0071566 | inferred from sequence or structural similarity with HGNC:23230 protein ufmylation ; GO:0071569 | inferred from sequence or structural similarity with HGNC:23230 locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype molybdopterin synthase complex ; GO:0019008 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:23230 "CG1749, dMoaD, MoeB, Uba5, dUBA5" "IPR000594:THIF-type NAD/FAD binding fold, IPR029752:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1" CG1749 11-Aug-17 DroID_v2017_08 Drer\uba5 Scer\UBA4 Cele\uba-5 Xtro\uba5 Mmus\Uba5 Hsap\UBA5 "lethal,some die during pupal stage,viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0259317 C17 - http://flybase.org/reports/FBgn0259317 gene - - - C17 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0024900 anon-a5 anon-a5 http://flybase.org/reports/FBgn0024900 - repeat_region - - - "a5, anon-a5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001715 l(1)ESHS36 lethal (1) ESHS36 http://flybase.org/reports/FBgn0001715 - gene - - - l(1)ESHS36 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016126 CaMKI Calcium/calmodulin-dependent protein kinase I http://flybase.org/reports/FBgn0016126 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from biological aspect of ancestor with PANTHER:PTN001218105 calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from sequence or structural similarity calmodulin binding ; GO:0005516 | traceable author statement protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from sequence or structural similarity intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 "caMKI, Calcium/calmodulin-dependent protein kinase, CamKI, CG1495, camKI, dCKI, CaMKI, CaMK1, CamK1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG1495 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-27e6.1, Drer\spegb, Drer\stk33, Drer\camk2b, Drer\mylk4b, Drer\stk17b, Drer\camkvb, Drer\dapk2a, Drer\si:dkey-240h12.4, Drer\camk1ga, Drer\dapk2b, Drer\capslb, Drer\camk1a, Drer\uhmk1, Drer\triob, Drer\camk2a, Drer\pskh1, Drer\camk1db, Drer\mylk4a, Drer\camk2d1, Drer\camk1gb, Drer\trioa, Drer\ttnb, Drer\camk1b, Drer\camk1da, Drer\camkvl, Drer\camk4, Drer\camk2g2, Drer\camkva, Drer\zgc:153952, Drer\capsla, Drer\camk2g1, Drer\stk17a, Drer\camk2d2, Drer\pnck, Drer\si:ch73-60h1.1, Drer\dapk3, Drer\dapk1, Drer\camk2b1, Drer\mylk3" "Scer\IKS1, Scer\DUN1, Scer\CMK1, Scer\CMK2, Scer\TDA1, Scer\RCK1, Scer\RCK2, Scer\MEK1, Scer\PRR1" "Cele\R06A10.4, Cele\cmk-1" "Xtro\pskh1, Xtro\capsl, Xtro\pnck, Xtro\camk1, Xtro\caps, Xtro\kalrn, Xtro\camk4, Xtro\camkv, Xtro\stk33, Xtro\dapk3, Xtro\camk1d, Xtro\trio, Xtro\mylk4, Xtro\dapk2, Xtro\camk1g, Xtro\mylk3, Xtro\dapk1, Xtro\pskh2, Xtro\stk17a, Xtro\dclk2" "Mmus\Camk1d, Mmus\Mylk3, Mmus\Dclk2, Mmus\Obscn, Mmus\Stk33, Mmus\Mylk4, Mmus\Pnck, Mmus\Trio, Mmus\Dapk1, Mmus\Speg, Mmus\Dapk2, Mmus\Stk17b, Mmus\Camk1g, Mmus\Mylk2, Mmus\Dclk1, Mmus\Camkv, Mmus\Dapk3, Mmus\Camk2g, Mmus\Camk2a, Mmus\Capsl, Mmus\Camk1, Mmus\Caps2, Mmus\Pskh1, Mmus\Camk2b, Mmus\Camk4, Mmus\Uhmk1" "Hsap\PNCK, Hsap\MYLK4, Hsap\DAPK1, Hsap\CAPSL, Hsap\DAPK2, Hsap\CAMK4, Hsap\CAPS, Hsap\STK17B, Hsap\CAMK2A, Hsap\CAMK1D, Hsap\PSKH2, Hsap\DCLK1, Hsap\CAMK1, Hsap\UHMK1, Hsap\OBSCN, Hsap\TRIO, Hsap\STK17A, Hsap\CAPS2, Hsap\CAMK2D, Hsap\CAMK2G, Hsap\CAMK1G, Hsap\DAPK3, Hsap\CAMK2B, Hsap\MYLK2, Hsap\SPEG, Hsap\MYLK3, Hsap\PSKH1, Hsap\STK33, Hsap\CAMKV" " adult stage , pupal stage&&larval stage&&adult stage " eye

"viable,fertile" FBgn0084036 CG41476 - http://flybase.org/reports/FBgn0084036 protein_coding_gene - - - CG41476 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035420 CG14967 - http://flybase.org/reports/FBgn0035420 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14967 "IPR019443:FMP27, C-terminal, IPR019441:FMP27, GFWDK domain, IPR019439:FMP27, N-terminal, IPR019409:FMP27, domain of unknown function DUF2405" CG14967 11-Aug-17 DroID_v2017_08 - "Scer\FMP27, Scer\YPR117W" Cele\F31C3.3 Xtro\kiaa0100 Mmus\2610507B11Rik Hsap\KIAA0100 viable FBgn0053738 snmRNA:430:CR33738 snmRNA:430:CR33738 http://flybase.org/reports/FBgn0053738 non_protein_coding_gene - - - "CR33738, snmRNA:430:CR33738" - CR33738 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052272 tRNA:Lys-CTT-1-13 transfer RNA:Lysine-CTT 1-13 http://flybase.org/reports/FBgn0052272 tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "CR32272, AE002584.trna20-LysCTT, tRNA[Lys][[2]], tRNA:lys2:63B, tRNA:K2:63B, tRNA:K2, tRNA:K:CTT:AE002584-b, chr3L.trna48-LysCTT, tRNA-Lys-CTT-1-13, tRNA:Lys-CTT-1-13, tRNA:CR32272, AAG" - CR32272 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263834 CR43696 - http://flybase.org/reports/FBgn0263834 pseudogene_attribute - - - CR43696 - CR43696 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060841 l(3)S049413b lethal (3) S049413b http://flybase.org/reports/FBgn0060841 gene - - - "0494/13, l(3)S049413b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036850 Gem2 Gemin2 http://flybase.org/reports/FBgn0036850 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spliceosomal complex assembly ; GO:0000245 | inferred from electronic annotation with InterPro:IPR017364 adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype spliceosomal snRNP assembly ; GO:0000387 | inferred from sequence or structural similarity with UniProtKB:O14893 ribonucleoprotein complex assembly ; GO:0022618 | inferred from direct assay spliceosomal snRNP assembly ; GO:0000387 | inferred from direct assay flight behavior ; GO:0007629 | inferred from mutant phenotype spliceosomal complex ; GO:0005681 | inferred from electronic annotation with InterPro:IPR017364 SmD-containing SMN-Sm protein complex ; GO:0034730 | inferred from direct assay SMN-Gemin2 complex ; GO:0034718 | inferred from direct assay SMN complex ; GO:0032797 | inferred from genetic interaction with Gem3 cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay "Gem2, CG10419, dGem2" IPR017364:Gem-associated protein 2 CG10419 11-Aug-17 DroID_v2017_08 Drer\gemin2 Scer\YLR053C "Cele\col-122, Cele\smi-1" Xtro\gemin2 Mmus\Gemin2 "Hsap\SMAD4, Hsap\GEMIN2" "lethal,heat sensitive,gravitaxis defective,progressive,flight defective,short lived,partially lethal - majority die,some die during pupal stage" FBgn0034638 CG10433 - http://flybase.org/reports/FBgn0034638 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response ; GO:0006952 | inferred from sequence or structural similarity regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model CG10433 - CG10433 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable" FBgn0025131 su(RpII140[Z36])S16 su(RpII140[Z36])S16 http://flybase.org/reports/FBgn0025131 - gene - - - "Z36[S16], su(RpII140[Z36])S16" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010307 mod(r)2 modulator of rudimentary 2 http://flybase.org/reports/FBgn0010307 - gene - - - mod(r)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262694 Su(VGlut)B14 - http://flybase.org/reports/FBgn0262694 gene - - - "Su(VGlut)B14, B14" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053056 CG33056 - http://flybase.org/reports/FBgn0053056 protein_coding_gene purine nucleoside binding ; GO:0001883 | inferred from sequence or structural similarity with HGNC:21257 purine nucleoside metabolic process ; GO:0042278 | inferred from sequence or structural similarity with HGNC:21257 cellular_component ; GO:0005575 | no biological data available "CG10517, CG33056" IPR002589:Macro domain CG33056 11-Aug-17 DroID_v2017_08 "Drer\zgc:113436, Drer\oard1" Scer\POA1 "Cele\F54G2.2, Cele\fbxb-37, Cele\W08F4.12" - Mmus\Oard1 Hsap\OARD1 "viable,visible" "trichogen cell,supernumerary" FBgn0044076 E(rst)I12 E(rst)I12 http://flybase.org/reports/FBgn0044076 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "I12, E(rst)I12" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262881 CG43236 - http://flybase.org/reports/FBgn0262881 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43236 - CG43236 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060619 l(3)S088712b lethal (3) S088712b http://flybase.org/reports/FBgn0060619 gene - - - "0887/12, l(3)S088712b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267268 CR45704 - http://flybase.org/reports/FBgn0267268 non_protein_coding_gene - - - CR45704 - CR45704 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060910 l(3)S042834a lethal (3) S042834a http://flybase.org/reports/FBgn0060910 gene - - - "0428/34, l(3)S042834a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0002820 ms(2)10R male sterile (2) 10R http://flybase.org/reports/FBgn0002820 - gene - - - ms(2)10R - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female fertile" "spermatid axoneme,spermatid,spermatid & nucleus,Nebenkern derivative" FBgn0025772 l(3)89Ac lethal (3) 89Ac http://flybase.org/reports/FBgn0025772 - gene - - - l(3)89Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054000 CG34000 - http://flybase.org/reports/FBgn0054000 protein_coding_gene - - - "BP1067, CG34000" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033698 CG8858 - http://flybase.org/reports/FBgn0033698 protein_coding_gene protein complex scaffold ; GO:0032947 | inferred from electronic annotation with InterPro:IPR024372 molecular_function ; GO:0003674 | no biological data available proteasome assembly ; GO:0043248 | inferred from electronic annotation with InterPro:IPR024372 biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P38737 proteasome complex ; GO:0000502 | inferred from sequence or structural similarity with UniProtKB:P38737 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P38737 CG8858 "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024372:Proteasome component Ecm29" CG8858 11-Aug-17 DroID_v2017_08 Drer\kiaa0368 Scer\ECM29 "Cele\D2045.2, Cele\H04D03.3" Xtro\kiaa0368 Mmus\AI314180 Hsap\KIAA0368 viable FBgn0038235 CG8461 - http://flybase.org/reports/FBgn0038235 protein_coding_gene - "cleavage involved in rRNA processing ; GO:0000469 | inferred from electronic annotation with InterPro:IPR009292 neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000497661" 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000497661 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000497661 CG8461 IPR009292:rRNA biogenesis protein RRP36 CG8461 11-Aug-17 DroID_v2017_08 Drer\rrp36 Scer\RRP36 Cele\T22H9.1 Xtro\klhdc3 Mmus\Rrp36 Hsap\RRP36 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0003495 spz spatzle http://flybase.org/reports/FBgn0003495 - protein_coding_gene Toll binding ; GO:0005121 | traceable author statement Toll binding ; GO:0005121 | non-traceable author statement growth factor activity ; GO:0008083 | inferred from mutant phenotype Toll binding ; GO:0005121 | inferred from physical interaction with Tl protein homodimerization activity ; GO:0042803 | inferred from direct assay Toll binding ; GO:0005121 | inferred from genetic interaction with Tl morphogen activity ; GO:0016015 | non-traceable author statement cytokine activity ; GO:0005125 | traceable author statement "innate immune response ; GO:0045087 | inferred from direct assay larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from direct assay Toll signaling pathway ; GO:0008063 | traceable author statement defense response to fungus ; GO:0050832 | inferred from mutant phenotype defense response ; GO:0006952 | inferred from mutant phenotype defense response ; GO:0006952 | traceable author statement immune response ; GO:0006955 | traceable author statement positive regulation of antifungal peptide biosynthetic process ; GO:0006967 | inferred from mutant phenotype response to fungus ; GO:0009620 | traceable author statement oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from expression pattern dorsal/ventral axis specification ; GO:0009950 | traceable author statement dorsal/ventral axis specification ; GO:0009950 | inferred from genetic interaction with pip dorsal/ventral axis specification ; GO:0009950 | non-traceable author statement defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | traceable author statement innate immune response ; GO:0045087 | non-traceable author statement Toll signaling pathway ; GO:0008063 | non-traceable author statement antifungal humoral response ; GO:0019732 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from direct assay embryonic axis specification ; GO:0000578 | non-traceable author statement regulation of Toll signaling pathway ; GO:0008592 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria ; GO:0006965 | inferred from mutant phenotype positive regulation of protein complex assembly ; GO:0031334 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | traceable author statement" extracellular region ; GO:0005576 | traceable author statement extracellular region ; GO:0005576 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Tl "Spz, spz, CG6134, mel(3)7, SPZ, Spz1, CT19282" "IPR029034:Cystine-knot cytokine, IPR032104:Spaetzle" CG6134 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage && adult stage | female , embryonic stage | 0-2 hr " ovary

"wild-type,immune response defective,recessive,lethal,maternal effect,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,dominant,partially lethal,neuroanatomy defective,locomotor rhythm defective,conditional,viable" "embryo,maternal effect,embryonic/first instar larval cuticle,ventral,dorsal,embryonic/larval somatic muscle,ventral furrow,supernumerary,ectopic,lateral,embryonic/larval fat body,embryonic/larval hemocoel" FBgn0003923 snRNA:U2:38ABb small nuclear RNA U2 at 38ABb http://flybase.org/reports/FBgn0003923 FBgn0003919 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay "U2:38ABb, U2, dU2, U2 snRNA, U2-38ABb, snRNA[[1]], K6, Dm U2-141B, U2-141B, D.U2-4, 141B, U2 141B, snRNA-U2-141B, snRNA:U2:40AB, snRNA:U2, snRNA2, snRNA1, U2snRNA40AB, CR32878, U2snRNA, snRNA:U2:38ABb, U2:39AB, 38A U2, chr2L:19808533..19808709" - CR32878 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038098 CG7381 - http://flybase.org/reports/FBgn0038098 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT22687, CG7381" IPR006149:EB domain CG7381 11-Aug-17 DroID_v2017_08 - - "Cele\D1044.7, Cele\pqn-25" - - - viable FBgn0038507 CG5863 - http://flybase.org/reports/FBgn0038507 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein autoprocessing ; GO:0016540 | inferred from electronic annotation with InterPro:IPR033145 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 - CG5863 "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR033145:Cathepsin E, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG5863 11-Aug-17 DroID_v2017_08 "Drer\ctsd, Drer\zgc:103530, Drer\nots, Drer\zgc:63831, Drer\ren" "Scer\YPS5, Scer\BAR1, Scer\YPS6, Scer\MKC7, Scer\YPS1, Scer\YGL258W-A, Scer\PEP4, Scer\YPS3, Scer\YPS7" "Cele\asp-9, Cele\asp-18, Cele\asp-12, Cele\asp-1, Cele\asp-13, Cele\asp-4, Cele\asp-10, Cele\asp-19, Cele\asp-8, Cele\asp-14, Cele\asp-17, Cele\asp-6, Cele\asp-3, Cele\asp-15, Cele\asp-7, Cele\asp-16, Cele\asp-5, Cele\asp-2" "Xtro\ren, Xtro\ctse, Xtro\ctsd, Xtro\LOC496913, Xtro\pgc, Xtro\bace1, Xtro\napsa, Xtro\bace2, Xtro\pga4" "Mmus\Bace2, Mmus\Ctsd, Mmus\Bace1, Mmus\Cym, Mmus\Ctse, Mmus\Pgc, Mmus\Ren1, Mmus\Napsa, Mmus\Ren2, Mmus\Pga5" "Hsap\BACE1, Hsap\PGC, Hsap\PGA4, Hsap\REN, Hsap\PGA5, Hsap\NAPSA, Hsap\CTSE, Hsap\CTSD, Hsap\BACE2, Hsap\PGA3" "viable,fertile" FBgn0050237 tRNA:Gln-CTG-1-1 transfer RNA:Glutamine-CTG 1-1 http://flybase.org/reports/FBgn0050237 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002787.trna14-GlnCTG, tRNA:Q:CTG:AE002787, CR30237, chr2R.trna73-GlnCTG, tRNA:Gln-CTG-1-1, tRNA:CR30237, tRNA-Gln-CTG-1-1, CAG" - CR30237 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261535 l(2)34Fd lethal (2) 34Fd http://flybase.org/reports/FBgn0261535 protein_coding_gene - - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012580 "CG7516, l(2)34Fd, l(2)br15, br15, A4, BG:DS01068.6" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR012580:NUC153, IPR017986:WD40-repeat-containing domain" CG7516 11-Aug-17 DroID_v2017_08 Drer\nol10 Scer\ENP2 Cele\nol-10 Xtro\nol10 Mmus\Nol10 Hsap\NOL10 FBgn0003683 term terminus http://flybase.org/reports/FBgn0003683 FBgn0036792 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "ter, Term, CG4216, Bsg75C, term" IPR013087:Zinc finger C2H2-type CG4216 11-Aug-17 DroID_v2017_08 - Scer\FUS1 "Cele\edc-3, Cele\nhr-45" - Mmus\Aoc1 - FBgn0039833 CG15564 - http://flybase.org/reports/FBgn0039833 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15564 - CG15564 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0261678 M(2)59B Minute (2) 59B http://flybase.org/reports/FBgn0261678 gene - - - "M(2)59B, RpL23" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034132 S-Lap8 Sperm-Leucylaminopeptidase 8 http://flybase.org/reports/FBgn0034132 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "anon-WO0140519.41, CG4439, S-Lap8, S-LAP 8" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG4439 11-Aug-17 DroID_v2017_08 "Drer\zgc:152830, Drer\rfwd2, Drer\npepl1, Drer\lap3" - "Cele\lap-1, Cele\lap-2" "Xtro\rfwd2, Xtro\lap3" "Mmus\Rfwd2, Mmus\Npepl1, Mmus\Lap3" "Hsap\NPEPL1, Hsap\LAP3" viable DRSC21372 K 0.439770231 0.398592919 0.089189963 -0.980274059 0.904633889 1.558873231 FBgn0032120 CG33298 - http://flybase.org/reports/FBgn0032120 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006539 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR006539 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from sequence or structural similarity with SGD:S000000024 intracellular protein transport ; GO:0006886 | inferred from genetic interaction with Osbp phospholipid translocation ; GO:0045332 | inferred from sequence or structural similarity with SGD:S000000024 response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from genetic interaction with Osbp "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR006539 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000642368" "CG18419, CG13112, CG33298, DmCG33298" "IPR001757:P-type ATPase, IPR006539:P-type ATPase, subfamily IV, IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N, IPR032630:P-type ATPase, C-terminal, IPR032631:P-type ATPase, N-terminal" CG33298 11-Aug-17 DroID_v2017_08 "Drer\atp8b4, Drer\atp8a1, Drer\atp8a2, Drer\atp10b, Drer\atp8b3, Drer\atp8b5b, Drer\atp8b1, Drer\atp11c, Drer\atp10a, Drer\atp11a, Drer\atp10d, Drer\atp8b5a" "Scer\DNF2, Scer\DNF3, Scer\DRS2, Scer\DNF1" "Cele\tat-4, Cele\tat-2, Cele\tat-3" "Xtro\atp8b3, Xtro\atp10a, Xtro\atp11c, Xtro\atp11a, Xtro\atp8b1, Xtro\LOC100490503, Xtro\atp11b, Xtro\atp8b4, Xtro\atp8a1, Xtro\atp10d" "Mmus\Atp8a1, Mmus\Atp10b, Mmus\Atp11a, Mmus\Atp11b, Mmus\Atp11c, Mmus\Atp10d, Mmus\Atp8b3, Mmus\Atp8a2, Mmus\Atp8b2, Mmus\Atp8b4, Mmus\Atp10a, Mmus\Atp8b1, Mmus\Atp8b5" "Hsap\ATP11B, Hsap\ATP10B, Hsap\ATP8A2, Hsap\ATP8B4, Hsap\ATP8B1, Hsap\ATP10A, Hsap\ATP8B3, Hsap\ATP11C, Hsap\ATP10D, Hsap\ATP8A1, Hsap\ATP11A, Hsap\ATP8B2" viable DRSC02672 IK 1.613799992 0.10515359 -0.17819812 0.11138554 1.739709757 0.726226242 FBgn0265958 CR44745 - http://flybase.org/reports/FBgn0265958 non_protein_coding_gene - - - CR44745 - CR44745 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065253 l(2)SH2113 lethal (2) SH2113 http://flybase.org/reports/FBgn0065253 gene - - - "l(2)SH2113, l(2)SH2 2113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020556 bxd bithoraxoid http://flybase.org/reports/FBgn0020556 "FBgn0051273, FBgn0051277" non_protein_coding_gene - "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from expression pattern" nucleus ; GO:0005634 | inferred from direct assay "CR31277, CR31273, bxd" - CR31273 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015880 anon-48Ai anon-48Ai http://flybase.org/reports/FBgn0015880 - gene - - - "XI, anon-48Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005541 l(3)72Di lethal (3) 72Di http://flybase.org/reports/FBgn0005541 - gene - - - l(3)72Di - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal organism FBgn0259602 B0911 - http://flybase.org/reports/FBgn0259602 gene - - - B0911 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein L3,anterior crossvein,antennal segment,arista,tarsal segment,unguis" FBgn0023111 anon-10Aw anon-10Aw http://flybase.org/reports/FBgn0023111 - gene - - - "16, anon-10Aw" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267052 CR45496 - http://flybase.org/reports/FBgn0267052 pseudogene_attribute - - - CR45496 - CR45496 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053263 CG33263 - http://flybase.org/reports/FBgn0053263 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG14106, CG33263" IPR002557:Chitin binding domain CG33263 11-Aug-17 DroID_v2017_08 - - "Cele\cbd-1, Cele\W03F11.1" - - - FBgn0262959 T:SS-Lcp2 Signal sequence of Lcp2 http://flybase.org/reports/FBgn0262959 engineered_tag - - - "T:SS-Lcp2, T:Lcp2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035035 CG3570 - http://flybase.org/reports/FBgn0035035 protein_coding_gene rRNA (adenine) methyltransferase activity ; GO:0016433 | inferred from biological aspect of ancestor with PANTHER:PTN001842290 - nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN001842290 CG3570 "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR021867:25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2" CG3570 11-Aug-17 DroID_v2017_08 Drer\zgc:153606 - - Xtro\c7orf60 Mmus\Bmt2 Hsap\BMT2 viable FBgn0267741 CR46072 - http://flybase.org/reports/FBgn0267741 pseudogene_attribute - - - CR46072 - CR46072 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000469 dlmd dorsal longitudinal muscle-defective http://flybase.org/reports/FBgn0000469 - gene - - - dlmd - - 11-Aug-17 DroID_v2017_08 - - - - - - "flight defective,dominant" FBgn0085737 CR40502 - http://flybase.org/reports/FBgn0085737 rRNA_gene - - - CR40502 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082183 l(4)CB-6471-3 lethal (4) CB-6471-3 http://flybase.org/reports/FBgn0082183 gene - - - l(4)CB-6471-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001413 l(1)3Ec lethal (1) 3Ec http://flybase.org/reports/FBgn0001413 - gene - - - l(1)3Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0039942 CG17163 - http://flybase.org/reports/FBgn0039942 protein_coding_gene - - - CG17163 - CG17163 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011607 l(1)I33h29 lethal (1) I33h29 http://flybase.org/reports/FBgn0011607 FBgn0010206 gene - - - "l(1)I33b29, l(1)33h29, l(1)I33h29" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069338 UY2129 UY2129 http://flybase.org/reports/FBgn0069338 gene - - - UY2129 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell" FBgn0019968 Khc-73 Kinesin heavy chain 73 http://flybase.org/reports/FBgn0019968 FBgn0025191 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 protein homodimerization activity ; GO:0042803 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" plus-end-directed vesicle transport along microtubule ; GO:0072383 | inferred from electronic annotation with InterPro:IPR032923 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cytoskeleton-dependent intracellular transport ; GO:0030705 | inferred from biological aspect of ancestor with PANTHER:PTN000648522 regulation of synapse structure or activity ; GO:0050803 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 establishment of spindle orientation ; GO:0051294 | inferred from mutant phenotype microtubule plus-end ; GO:0035371 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 astral microtubule ; GO:0000235 | colocalizes_with inferred from direct assay "CG8183, DmKlp73, DmKIN73, anon-EST:fe3C9, Khc-73, KLP73, Kinesin-73, Khc73, khc-73, DmKin73, Kin73, KIF 13A, KHC-73, KIF13A/B" "IPR000253:Forkhead-associated (FHA) domain, IPR000938:CAP Gly-rich domain, IPR001752:Kinesin motor domain, IPR008984:SMAD/FHA domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000008:C2 domain, IPR022140:Kinesin-like KIF1-type, IPR022164:Kinesin-like, IPR032405:Kinesin-associated, IPR032923:Kinesin-like protein KIF13" CG8183 11-Aug-17 DroID_v2017_08 "Drer\kif1aa, Drer\kif16ba, Drer\kif16bb, Drer\kif13a, Drer\stard9, Drer\kif14, Drer\si:rp71-84d9.2, Drer\kif1ab, Drer\kif1c, Drer\kif13bb, Drer\kif1b, Drer\kif13ba" "Scer\KIP2, Scer\KIP1, Scer\CIN8" "Cele\klp-4, Cele\klp-6, Cele\unc-104" "Xtro\kif1c, Xtro\kif16b, Xtro\kif14, Xtro\kif1b, Xtro\kif13b, Xtro\kif1a" "Mmus\Gm1305, Mmus\Kif13b, Mmus\Kif1c, Mmus\Stard9, Mmus\Kif13a, Mmus\Kif16b, Mmus\Kif14, Mmus\Kif1a, Mmus\Kif1b" "Hsap\KIF16B, Hsap\STARD9, Hsap\KIF13A, Hsap\KIF1A, Hsap\KIF1C, Hsap\KIF1B, Hsap\KIF13B, Hsap\KIF14" neurophysiology defective t-bar FBgn0266087 CR44829 - http://flybase.org/reports/FBgn0266087 non_protein_coding_gene - - - CR44829 - CR44829 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263210 CR43380 - http://flybase.org/reports/FBgn0263210 pseudogene_attribute - - - CR43380 - CR43380 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041118 l(2)k077 lethal (2) k077 http://flybase.org/reports/FBgn0041118 gene - - - l(2)k077 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022291 l(2)04518b lethal (2) 04518b http://flybase.org/reports/FBgn0022291 - gene - - - l(2)04518b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267428 CG45781 - http://flybase.org/reports/FBgn0267428 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG45781, CG42644, CG40378, 40378, CG43676" "IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype, IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2, IPR013098:Immunoglobulin I-set, IPR013106:Immunoglobulin V-set domain" CG45781 11-Aug-17 DroID_v2017_08 "Drer\pigrl4.2, Drer\mxra8a, Drer\zgc:153073, Drer\negr1, Drer\LOC100151468, Drer\igsf11, Drer\cxadr, Drer\si:zfos-1011f11.1, Drer\opcml, Drer\vsig8a, Drer\si:ch211-9d9.7, Drer\esamb, Drer\jam2b, Drer\mxra8b, Drer\vsig8b, Drer\jam3b, Drer\si:ch211-215e19.3, Drer\f11r.2, Drer\ntm, Drer\si:dkey-65b12.12, Drer\jam2a, Drer\jam3a, Drer\zgc:110372, Drer\cxcr3.1, Drer\lsamp, Drer\si:dkey-250k15.10, Drer\f11r.1, Drer\gpa33, Drer\esama" - Cele\rig-5 "Xtro\ntm, Xtro\negr1, Xtro\lsamp" "Mmus\Cxadr, Mmus\Jam3, Mmus\Igsf11, Mmus\Esam, Mmus\Mxra8, Mmus\Hepacam2, Mmus\F11r, Mmus\Vsig1, Mmus\Jam2, Mmus\Lsamp, Mmus\Gm1123, Mmus\Negr1, Mmus\Clmp, Mmus\Iglon5, Mmus\Ntm, Mmus\Gpa33, Mmus\Vsig2, Mmus\Vsig8, Mmus\Opcml, Mmus\Vsir, Mmus\Igsf5" "Hsap\VSIG8, Hsap\IGSF11, Hsap\MXRA8, Hsap\ESAM, Hsap\F11R, Hsap\LSAMP, Hsap\CLMP, Hsap\VSIG1, Hsap\OPCML, Hsap\CXADR, Hsap\GPA33, Hsap\JAM2, Hsap\NTM, Hsap\JAM3, Hsap\IGLON5, Hsap\NEGR1, Hsap\C10orf54, Hsap\EMB, Hsap\IGSF5, Hsap\C1orf204, Hsap\VSIG2" FBgn0011948 tRNA:Arg-TCG-3-1 transfer RNA:Arginine-TCG 3-1 http://flybase.org/reports/FBgn0011948 "FBgn0011947, FBgn0052622, FBgn0060082" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna4-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-b, CR32622, tRNA:arg12Ea, chrX.trna8-ArgTCG, tRNA-Arg-TCG-3-1, tRNA:Arg-TCG-3-1, tRNA:R:12Ea, CGA" - CR32622 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085516 CG40769 - http://flybase.org/reports/FBgn0085516 protein_coding_gene - - - CG40769 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039331 ND-49L NADH dehydrogenase (ubiquinone) 49 kDa subunit-like http://flybase.org/reports/FBgn0039331 protein_coding_gene NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR001135 quinone binding ; GO:0048038 | inferred from electronic annotation with InterPro:IPR001135 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95299 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95299" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95299 "CG111913, CG11913, Q9VBR4_DROME, NUCM, ND-49L" "IPR001135:NADH-quinone oxidoreductase, subunit D, IPR014029:NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site, IPR029014:NiFe hydrogenase-like, IPR022885:NAD(P)H-quinone oxidoreductase subunit D/H" CG11913 11-Aug-17 DroID_v2017_08 Drer\ndufs2 - "Cele\nduf-2.2, Cele\gas-1" Xtro\ndufs2 Mmus\Ndufs2 Hsap\NDUFS2 viable FBgn0051680 CG31680 - http://flybase.org/reports/FBgn0051680 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "BcDNA:AT19802, CG31680" - CG31680 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0050485 CG30485 - http://flybase.org/reports/FBgn0050485 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13342, CG30485" - CG30485 11-Aug-17 DroID_v2017_08 - - - - Mmus\Akap11 Hsap\AKAP11 viable FBgn0028645 beat-Ib beaten path Ib http://flybase.org/reports/FBgn0028645 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic integral component of plasma membrane ; GO:0005887 | inferred from sequence model "beat-B, beat Ib, CT23325, BG:DS00365.4, CG7644, BcDNA:RE51929, beat-Ib, Beat-Ib" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG7644 11-Aug-17 DroID_v2017_08 "Drer\zgc:172106, Drer\f11r.2, Drer\jam2b" - - Xtro\f11r - Hsap\CADM2 "viable,fertile" FBgn0010295 ng3 new glue 3 http://flybase.org/reports/FBgn0010295 FBgn0063122 protein_coding_gene - - - "ng-3, ng, EG:96G10.3, CG10788, BcDNA:LP03924, ng3" - CG10788 11-Aug-17 DroID_v2017_08 - - - - - - larval stage | third instar embryonic/larval salivary gland

viable FBgn0266136 Gyc76C Guanylyl cyclase at 76C http://flybase.org/reports/FBgn0266136 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 guanylate cyclase activity ; GO:0004383 | inferred from direct assay receptor activity ; GO:0004872 | inferred from direct assay semaphorin receptor binding ; GO:0030215 | inferred from physical interaction with PlexA protein kinase activity ; GO:0004672 | NOT inferred from sequence or structural similarity with CG10738 guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 peptide receptor activity ; GO:0001653 | inferred from physical interaction with Nplp1 "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245 motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with PlexA response to salt stress ; GO:0009651 | inferred from mutant phenotype cGMP-mediated signaling ; GO:0019934 | inferred from direct assay salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype inferred from genetic interaction with LanB2 extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 primary branching, open tracheal system ; GO:0007428 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with Sema1a inferred from genetic interaction with PlexA" integral component of plasma membrane ; GO:0005887 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 "CG42636, CG8742, gyc76C, Gyc76C, l(3)76BDl, DrGC-1, GYC 76C, DGC1, drgc, CG32215, l(3)L0090, gim" "IPR029787:Nucleotide cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR000719:Protein kinase domain, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001828:Receptor, ligand binding region, IPR011009:Protein kinase-like domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR028082:Periplasmic binding protein-like I" CG42636 11-Aug-17 DroID_v2017_08 "Drer\gucy2g, Drer\npr3, Drer\si:dkey-37g12.1, Drer\si:ch73-139e5.4, Drer\gucy2c, Drer\npr1a, Drer\ints3, Drer\gc2, Drer\gc3, Drer\npr1b, Drer\npr2, Drer\gucy2f" - "Cele\gcy-20, Cele\gcy-21, Cele\gcy-11, Cele\gcy-29, Cele\gcy-4, Cele\gcy-19, Cele\gcy-2, Cele\gcy-12, Cele\gcy-9, Cele\gcy-1, Cele\gcy-6, Cele\gcy-17, Cele\gcy-25, Cele\gcy-14, Cele\Y92H12A.4, Cele\gcy-28, Cele\gcy-7, Cele\gcy-22, Cele\gcy-5, Cele\gcy-8, Cele\gcy-18, Cele\gcy-13, Cele\gcy-27, Cele\gcy-15, Cele\gcy-23, Cele\daf-11, Cele\odr-1, Cele\gcy-3" "Xtro\gucy2d, Xtro\gucy2c, Xtro\gucy2f, Xtro\npr1, Xtro\npr3" "Mmus\Gucy2f, Mmus\Npr1, Mmus\Ints3, Mmus\Gucy2d, Mmus\Gucy2e, Mmus\Gucy2c, Mmus\Npr2, Mmus\Npr3, Mmus\Gucy2g" "Hsap\GUCY2D, Hsap\GUCY2F, Hsap\GUCY2C, Hsap\NPR2, Hsap\NPR3, Hsap\NPR1, Hsap\INTS3" " embryonic stage -- adult stage , adult stage , embryonic stage | late , adult stage && oogenesis stage , embryonic stage | early " " adult midgut

, adult brain

, adult proventriculus

, embryonic/larval somatic muscle

, retina

, larval visceral muscle

, oocyte

, optic lobe

, pupal/adult digestive system

,

ubiquitous " FBgn0039798 CG11313 - http://flybase.org/reports/FBgn0039798 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 hemolymph coagulation ; GO:0042381 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence model" extracellular region ; GO:0005576 | inferred from direct assay "CG11313, SP11, c-SP11" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG11313 11-Aug-17 DroID_v2017_08 Drer\st14b - "Cele\svh-1, Cele\try-1" - "Mmus\Klk1b1, Mmus\Klk1b5" Hsap\KLK1 FBgn0032394 CG6746 - http://flybase.org/reports/FBgn0032394 protein_coding_gene enzyme binding ; GO:0019899 | inferred from sequence or structural similarity with HGNC:9639 fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with HGNC:9639 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:9639 "CG6746, HADC[CG6746]" "IPR007482:Protein-tyrosine phosphatase-like, PTPLA" CG6746 11-Aug-17 DroID_v2017_08 "Drer\hacd1, Drer\hacd3, Drer\hacd2" Scer\PHS1 Cele\hpo-8 "Xtro\hacd2, Xtro\hacd1" "Mmus\Hacd3, Mmus\Hacd4, Mmus\Hacd1, Mmus\Hacd2" "Hsap\HACD3, Hsap\HACD1, Hsap\HACD4, Hsap\HACD2" lethal FBgn0033631 Sod3 Superoxide dismutase 3 http://flybase.org/reports/FBgn0033631 protein_coding_gene superoxide dismutase activity ; GO:0004784 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 superoxide dismutase activity ; GO:0004784 | inferred from direct assay superoxide dismutase activity ; GO:0004784 | inferred from mutant phenotype copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001424, InterPro:IPR018152 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype UV protection ; GO:0009650 | inferred from direct assay removal of superoxide radicals ; GO:0019430 | inferred from mutant phenotype removal of superoxide radicals ; GO:0019430 | inferred from biological aspect of ancestor with PANTHER:PTN000000113" extracellular space ; GO:0005615 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000000114 plasma membrane ; GO:0005886 | inferred from direct assay "CG13200, CT25938, Sod3, dSod3, Dmel/CG9027, CG9027, SOD3" "IPR001424:Superoxide dismutase, copper/zinc binding domain, IPR018152:Superoxide dismutase, copper/zinc, binding site" CG9027 11-Aug-17 DroID_v2017_08 "Drer\sod3a, Drer\sod3b, Drer\sod1" "Scer\CCS1, Scer\SOD1" "Cele\sod-4, Cele\sod-5, Cele\sod-1" "Xtro\sod3, Xtro\sod1" "Mmus\Sod1, Mmus\Sod3" "Hsap\SOD3, Hsap\SOD1" "oxidative stress response defective,short lived,viable,body color defective" mesothoracic tergum FBgn0026678 l(1)G0104 lethal (1) G0104 http://flybase.org/reports/FBgn0026678 - gene - - - l(1)G0104 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0005420 l(1)adl9 lethal (1) adl9 http://flybase.org/reports/FBgn0005420 - gene - - - "l(1)adl-9, l(1)adl9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,heat sensitive,partially lethal - majority die,lethal" FBgn0032061 CG9314 - http://flybase.org/reports/FBgn0032061 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 catalase activity ; GO:0004096 | inferred from sequence or structural similarity with UniProtKB:P04762 catalase activity ; GO:0004096 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR011614, InterPro:IPR018028, InterPro:IPR020835, InterPro:IPR024711 response to hydrogen peroxide ; GO:0042542 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 hydrogen peroxide catabolic process ; GO:0042744 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 response to oxidative stress ; GO:0006979 | inferred from sequence or structural similarity with UniProtKB:P04762" peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000157252 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000157252 "CT26521, anon-WO0140519.249, CG9314, CatB" "IPR002226:Catalase haem-binding site, IPR011614:Catalase core domain, IPR010582:Catalase immune-responsive domain, IPR018028:Catalase, mono-functional, haem-containing, IPR020835:Catalase-like domain, IPR024711:Catalase, mono-functional, haem-containing, clades 1 and 3" CG9314 11-Aug-17 DroID_v2017_08 Drer\cat "Scer\CTT1, Scer\CTA1" "Cele\ctl-3, Cele\ctl-1, Cele\ctl-2" "Xtro\cat.2, Xtro\cat.1" Mmus\Cat Hsap\CAT "viable,visible" "adult heart,RU486 conditional,trichogen cell" FBgn0065175 l(3)SH016 lethal (3) SH016 http://flybase.org/reports/FBgn0065175 gene - - - "l(3)SH016, l(2)SH3 016" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037500 CG17944 - http://flybase.org/reports/FBgn0037500 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17944 - CG17944 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC12572 I 0.753408372 -1.940362737 -0.196981762 0.253008363 0.212101108 0.234536605 FBgn0040509 ACXB ACXB http://flybase.org/reports/FBgn0040509 protein_coding_gene adenylate cyclase activity ; GO:0004016 | inferred from sequence model adenylate cyclase activity ; GO:0004016 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054 spermatogenesis ; GO:0007283 | inferred from expression pattern signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 integral component of membrane ; GO:0016021 | inferred from sequence model" "CG17174, AC, DACXB, AC34A, Ac34A, ACXB" "IPR029787:Nucleotide cyclase, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase" CG17174 11-Aug-17 DroID_v2017_08 "Drer\adcy1a, Drer\adcy2a, Drer\adcy3a, Drer\adcy7, Drer\adcy2b, Drer\si:dkey-206f10.1, Drer\adcy6a, Drer\adcy1b, Drer\adcy5, Drer\adcy6b, Drer\si:ch211-132f19.7, Drer\adcy8" - "Cele\acy-4, Cele\acy-2" "Xtro\dnajc27, Xtro\adcy6, Xtro\adcy7, Xtro\adcy1, Xtro\adcy4" "Mmus\Adcy5, Mmus\Adcy1, Mmus\Adcy2, Mmus\Adcy3, Mmus\Adcy4, Mmus\Adcy8, Mmus\Adcy7, Mmus\Adcy6" "Hsap\ADCY5, Hsap\ADCY1, Hsap\ADCY7, Hsap\ADCY6, Hsap\ADCY3, Hsap\ADCY4, Hsap\ADCY2, Hsap\ADCY8" " pupal stage , larval stage | late , adult stage | male && spermatogenesis , adult stage | male " " spermatid | early

, spermatocyte

" viable FBgn0028128 l(3)S056113 lethal (3) S056113 http://flybase.org/reports/FBgn0028128 gene - - - "0561/13, l(3)S056113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051036 CG31036 - http://flybase.org/reports/FBgn0051036 protein_coding_gene - - cilium ; GO:0005929 | colocalizes_with inferred from direct assay "CG15518, CG15516, CG31036" - CG31036 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028977 v(2)k06408 v(2)k06408 http://flybase.org/reports/FBgn0028977 gene - - - v(2)k06408 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" FBgn0061066 l(3)S020202 lethal (3) S020202 http://flybase.org/reports/FBgn0061066 gene - - - "0202/02, l(3)S020202" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035952 CG5280 - http://flybase.org/reports/FBgn0035952 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5280 IPR007914:Uncharacterised protein family UPF0193 CG5280 11-Aug-17 DroID_v2017_08 Drer\si:dkey-43k4.3 - - Xtro\c4h22orf23 Mmus\1700088E04Rik Hsap\C22orf23 viable FBgn0040215 fs(3)BQ16 fs(3)BQ16 http://flybase.org/reports/FBgn0040215 gene - - - fs(3)BQ16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0026562 SPARC "Secreted protein, acidic, cysteine-rich" http://flybase.org/reports/FBgn0026562 FBgn0027691 protein_coding_gene collagen binding ; GO:0005518 | inferred from biological aspect of ancestor with PANTHER:PTN001015480 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN001015480 extracellular matrix binding ; GO:0050840 | inferred from biological aspect of ancestor with PANTHER:PTN001015480 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR019577 larval fat body development ; GO:0007504 | inferred from mutant phenotype anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype trachea development ; GO:0060438 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern cell adhesion ; GO:0007155 | inferred from sequence or structural similarity extracellular matrix constituent secretion ; GO:0070278 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype basement membrane assembly ; GO:0070831 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR019577 extracellular space ; GO:0005615 | colocalizes_with inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity "dsparc, BM-40/SPARC, dSPARC, SPARC, CG6378, BM40, CT19876, anon-EST:Posey291, BM-40-SPARC, Sparc, sparc, BM-40 Sparc, dSparc" "IPR001999:Osteonectin-like, conserved site, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR019577:SPARC/Testican, calcium-binding domain" CG6378 11-Aug-17 DroID_v2017_08 "Drer\sparcl2, Drer\fstl1b, Drer\sparcl1, Drer\sparc, Drer\fstl4" - Cele\ost-1 Xtro\sparc "Mmus\Fstl5, Mmus\Spock3, Mmus\Spock1, Mmus\Fstl4, Mmus\Fstl1, Mmus\Sparcl1, Mmus\Sparc" "Hsap\FSTL5, Hsap\SPOCK3, Hsap\SPARCL1, Hsap\SPARC, Hsap\SPOCK1, Hsap\SPOCK2, Hsap\FSTL4" "viable,lethal" "embryonic/first instar larval cuticle,presumptive embryonic/larval tracheal system,ventral nerve cord" FBgn0040764 CG13230 - http://flybase.org/reports/FBgn0040764 protein_coding_gene - - - CG13230 - CG13230 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034253 CG10936 - http://flybase.org/reports/FBgn0034253 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG10936 IPR000082:SEA domain CG10936 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0011869 tRNA:Gly-GCC-1-10 transfer RNA:Glycine-GCC 1-10 http://flybase.org/reports/FBgn0011869 "FBgn0003782, FBgn0050137, FBgn0050214, FBgn0060216" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "AE002787.trna58-GlyGCC, CR30137, tRNA:G:GCC:AE002787-c, CR30214, tRNA:gly3:56EFa, tRNA[Gly-GCC], chr2R.trna42-GlyGCC, tRNA-Gly-GCC-1-10, tRNA:Gly-GCC-1-10, tRNA:G3:56EFa, GGC" - CR30214 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262447 mir-14 mir-14 stem loop http://flybase.org/reports/FBgn0262447 miRNA_gene - "salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype negative regulation of programmed cell death ; GO:0043069 | inferred from genetic interaction with Dronc AND inferred from genetic interaction with hid AND inferred from genetic interaction with grim AND inferred from genetic interaction with rpr AND inferred from mutant phenotype regulation of lipid metabolic process ; GO:0019216 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype insulin-like growth factor receptor signaling pathway ; GO:0048009 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap negative regulation of apoptotic process ; GO:0043066 | traceable author statement regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype terminal cell fate specification, open tracheal system ; GO:0035154 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype" - "miR-14, dme-mir-14, mir-14, 14, MIR-14, CR43013, Mir-14, l(2)k10213, CR33010, mir14, dme-miR-14, miR14" - CR43013 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0001829 l(1)ts120 lethal (1) ts120 http://flybase.org/reports/FBgn0001829 - gene - - - l(1)ts120 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0267301 CR45737 - http://flybase.org/reports/FBgn0267301 non_protein_coding_gene - - - CR45737 - CR45737 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002685 mb minus bar http://flybase.org/reports/FBgn0002685 - gene - - - mb - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0011078 l(1)Q33 lethal (1) Q33 http://flybase.org/reports/FBgn0011078 FBgn0010210 gene - - - l(1)Q33 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0063261 CG31275 - http://flybase.org/reports/FBgn0063261 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR016561 lateral inhibition ; GO:0046331 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | non-traceable author statement cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR016561 dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG14908, BcDNA:GH08635, CG31275" IPR016561:Dynein light chain roadblock-type 1/2 CG31275 11-Aug-17 DroID_v2017_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb1, Mmus\Dynlrb2" "Hsap\DYNLRB1, Hsap\DYNLRB2" "viable,visible" chaeta FBgn0040536 CG12418 - http://flybase.org/reports/FBgn0040536 protein_coding_gene - - - CG12418 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031568 CG10019 - http://flybase.org/reports/FBgn0031568 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "GH25970, BEST:GH25970, CG10019" "IPR011701:Major facilitator superfamily, IPR015943:WD40/YVTN repeat-like-containing domain, IPR020846:Major facilitator superfamily domain" CG10019 11-Aug-17 DroID_v2017_08 "Drer\slc16a9b, Drer\slc16a9a" "Scer\MCH5, Scer\ESBP6, Scer\MCH4, Scer\MCH2, Scer\ATG22" "Cele\cat-1, Cele\gem-1" Xtro\slc16a9 "Mmus\Slc16a14, Mmus\Slc16a9" "Hsap\SLC16A9, Hsap\SLC16A14" viable FBgn0082631 S(CycE[JP])2.7 S(CycE[JP])2.7 http://flybase.org/reports/FBgn0082631 gene - - - S(CycE[JP])2.7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264521 ff19 - http://flybase.org/reports/FBgn0264521 gene - - - ff19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" spermatid FBgn0082975 snoRNA:Psi28S-3305b snoRNA:Psi28S-3305b http://flybase.org/reports/FBgn0082975 snoRNA_gene - - - "snoRNA:Psi28S-3305b, psi28s-3305b, CR34622" - CR34622 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033639 CG9003 - http://flybase.org/reports/FBgn0033639 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG9003, FBXL2" "IPR001810:F-box domain, IPR006553:Leucine-rich repeat, cysteine-containing subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG9003 11-Aug-17 DroID_v2017_08 "Drer\fbxl2, Drer\fbxl20, Drer\si:ch73-290k24.5, Drer\fbxl13, Drer\fbxl7, Drer\si:dkey-192l18.9" "Scer\RAD7, Scer\GRR1, Scer\AMN1" "Cele\fbxl-1, Cele\F07A11.4, Cele\EEED8.10" Xtro\fbxl20 "Mmus\Fbxl20, Mmus\Fbxl17, Mmus\Fbxl2, Mmus\Fbxl7, Mmus\Fbxl13" "Hsap\FBXL20, Hsap\FBXL7, Hsap\FBXL13, Hsap\FBXL17, Hsap\FBXL2" viable FBgn0259550 GG01430 - http://flybase.org/reports/FBgn0259550 gene - - - GG01430 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,anterior crossvein,tarsal segment,unguis,leg" FBgn0266183 CR44889 - http://flybase.org/reports/FBgn0266183 non_protein_coding_gene - - - CR44889 - CR44889 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032244 RfC3 Replication factor C subunit 3 http://flybase.org/reports/FBgn0032244 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000186208 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from sequence or structural similarity with SGD:S000005234 leading strand elongation ; GO:0006272 | inferred from sequence or structural similarity with SGD:S000005234 sister chromatid cohesion ; GO:0007062 | inferred from sequence or structural similarity with SGD:S000005234 lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA replication factor C complex ; GO:0005663 | inferred from sequence or structural similarity with SGD:S000005234 Elg1 RFC-like complex ; GO:0031391 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 "CG5313, RfC3, DRFC, Rfc3, DmRFC3" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR013748:Replication factor C, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5313 11-Aug-17 DroID_v2017_08 "Drer\rfc5, Drer\rfc2" "Scer\CTF18, Scer\RFC3" "Cele\rfc-2, Cele\rfc-4, Cele\F44B9.8" "Xtro\rfc4, Xtro\rfc5, Xtro\rfc2" "Mmus\Rfc4, Mmus\Rfc2, Mmus\Rfc5" "Hsap\RFC2, Hsap\RFC5" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0032708 CG15166 - http://flybase.org/reports/FBgn0032708 protein_coding_gene - - - CG15166 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052205 CR32205 - http://flybase.org/reports/FBgn0052205 pseudogene_attribute - - - "BcDNA:RE73739, CR32205, hp-CR32205" - CR32205 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016931 smi45E smell impaired 45E http://flybase.org/reports/FBgn0016931 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi45E - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0003258 rm rimy http://flybase.org/reports/FBgn0003258 - gene - - - rm - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,eye color defective,recessive,visible" "eye,wing" FBgn0022227 l(2)k03110 lethal (2) k03110 http://flybase.org/reports/FBgn0022227 FBgn0022243 gene - - - "l(2)k02203, l(2)k03110" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0028269 l(1)G0437 lethal (1) G0437 http://flybase.org/reports/FBgn0028269 gene - - - l(1)G0437 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0022333 f7 f7 http://flybase.org/reports/FBgn0022333 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available f7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,cytokinesis defective,male,recessive" "spermatocyte,primary spermatocyte cyst,onion stage spermatid,spermatozoon" FBgn0032115 CG4438 - http://flybase.org/reports/FBgn0032115 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:14634 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4438 "IPR019380:Casein kinase substrate, phosphoprotein PP28" CG4438 11-Aug-17 DroID_v2017_08 "Drer\pdap1a, Drer\pdap1b" - - Xtro\pdap1 Mmus\Pdap1 Hsap\PDAP1 viable FBgn0039789 CG9717 - http://flybase.org/reports/FBgn0039789 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 CG9717 "IPR002645:STAS domain, IPR011547:SLC26A/SulP transporter domain, IPR001902:SLC26A/SulP transporter" CG9717 11-Aug-17 DroID_v2017_08 "Drer\slc26a3.2, Drer\slc26a11, Drer\slc26a5, Drer\slc26a6l, Drer\slc26a2, Drer\slc26a4, Drer\slc26a3.1, Drer\si:ch211-117c9.2, Drer\slc26a6, Drer\slc26a1, Drer\slc26a10" "Scer\YGR125W, Scer\SUL2, Scer\SUL1, Scer\YPR003C" "Cele\sulp-7, Cele\sulp-2, Cele\sulp-5, Cele\sulp-1, Cele\sulp-4, Cele\sulp-3, Cele\sulp-6, Cele\sulp-8" "Xtro\slc26a2, Xtro\slc26a7, Xtro\slc26a4, Xtro\slc26a6, Xtro\slc26a10, Xtro\slc26a5, Xtro\slc26a1, Xtro\slc26a11, Xtro\slc26a9" "Mmus\Slc26a2, Mmus\Slc26a10, Mmus\Slc26a7, Mmus\Slc26a5, Mmus\Slc26a1, Mmus\Slc26a4, Mmus\Slc26a3, Mmus\Slc26a11, Mmus\Slc26a8, Mmus\Slc26a6, Mmus\Slc26a9" "Hsap\SLC26A8, Hsap\SLC26A5, Hsap\SLC26A10, Hsap\SLC26A3, Hsap\SLC26A11, Hsap\SLC26A6, Hsap\SLC26A4, Hsap\SLC26A9, Hsap\SLC26A1, Hsap\SLC26A7, Hsap\SLC26A2" viable FBgn0004748 l(3)89Ba lethal (3) 89Ba http://flybase.org/reports/FBgn0004748 - gene - - - l(3)89Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051353 CG31353 - http://flybase.org/reports/FBgn0051353 protein_coding_gene - - - CG31353 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC23083 K 0.109900945 1.529388491 FBgn0051882 CG31882 - http://flybase.org/reports/FBgn0051882 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs35a07.y1, NEST:bs35a07, CG31882" - CG31882 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267537 CR45877 - http://flybase.org/reports/FBgn0267537 non_protein_coding_gene - - - CR45877 - CR45877 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051337 CG31337 - http://flybase.org/reports/FBgn0051337 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE40816, CG31337" "IPR022700:Proteinase, regulatory CLIP domain" CG31337 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069226 gl(2L)50-27 gl(2L)50-27 http://flybase.org/reports/FBgn0069226 gene molecular_function ; GO:0003674 | no biological data available anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)50-27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryo,germline clone,maternal effect,posterior" FBgn0031233 Tbc1d15-17 TBC1 domain family member 15/17 http://flybase.org/reports/FBgn0031233 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab5 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 "CG11490, Tbc1d15-17" IPR000195:Rab-GTPase-TBC domain CG11490 11-Aug-17 DroID_v2017_08 "Drer\tbc1d15, Drer\tbc1d17, Drer\si:dkey-238d18.4, Drer\tbc1d25" Scer\GYP7 Cele\tbc-14 "Xtro\tbc1d17, Xtro\tbc1d15" "Mmus\Tbc1d17, Mmus\Tbc1d15, Mmus\Tbc1d25, Mmus\Tbc1d21" "Hsap\TBC1D17, Hsap\TBC1D21, Hsap\TBC1D25, Hsap\TBC1D15" "viable,fertile" FBgn0027603 Ulp1 Ulp1 http://flybase.org/reports/FBgn0027603 - protein_coding_gene SUMO-specific protease activity ; GO:0016929 | inferred from sequence or structural similarity with SGD:S000005941 protein binding ; GO:0005515 | inferred from physical interaction with krz SUMO-specific protease activity ; GO:0016929 | inferred from direct assay endopeptidase activity ; GO:0004175 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 central nervous system projection neuron axonogenesis ; GO:0021952 | inferred from mutant phenotype protein desumoylation ; GO:0016926 | inferred from sequence or structural similarity with SGD:S000005941 negative regulation of inflammatory response ; GO:0050728 | inferred from mutant phenotype negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype dendritic spine morphogenesis ; GO:0060997 | inferred from mutant phenotype negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from direct assay protein desumoylation ; GO:0016926 | inferred from mutant phenotype protein desumoylation ; GO:0016926 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from direct assay nuclear inner membrane ; GO:0005637 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Ulp1, CG12359, DmUlp1, BcDNA:GH02751, ulp1" "IPR003653:Ulp1 protease family, C-terminal catalytic domain" CG12359 11-Aug-17 DroID_v2017_08 "Drer\eif4a1a, Drer\senp8, Drer\senp3a, Drer\senp5, Drer\senp2, Drer\si:dkey-21c19.3, Drer\senp3b" Scer\ULP1 "Cele\K04F10.7, Cele\ulp-2, Cele\ulp-3, Cele\ulp-1" - "Mmus\Senp8, Mmus\Senp2, Mmus\Senp1, Mmus\4930444G20Rik, Mmus\Gm5415, Mmus\AF366264, Mmus\Senp3, Mmus\Gm9839, Mmus\Senp5" "Hsap\SENP8, Hsap\SENP2, Hsap\SENP1, Hsap\SENP5, Hsap\SENP3" "viable,fertile,male sterile,lethal,recessive,partially lethal - majority die,visible" "denticle belt,mesothoracic tergum" FBgn0003063 anon-Pen68A anon-Pen68A http://flybase.org/reports/FBgn0003063 - gene - - - "GCR-16, pen68A, Pen68A, GCR16, anon-Pen68A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039157 Myo95E Myosin 95E http://flybase.org/reports/FBgn0039157 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609 motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR010926" determination of left/right symmetry ; GO:0007368 | NOT inferred from mutant phenotype biological_process ; GO:0008150 | no biological data available "myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR010926" "CG5501, Dm95E, 95E, DmAE003746, CG31135, CG31134, Myo95E, myo 95E, Myo5" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site, IPR001609:Myosin head, motor domain, IPR010926:Class I myosin tail homology domain" CG5501 11-Aug-17 DroID_v2017_08 "Drer\myo1ea, Drer\si:dkeyp-92c9.3, Drer\si:ch211-94l19.4, Drer\myo1ca, Drer\myo1f, Drer\myo1hb, Drer\myo1ha, Drer\myo1cb, Drer\myo1eb, Drer\myo5c, Drer\myo1b" "Scer\MYO3, Scer\MYO5" "Cele\hum-9, Cele\hum-1, Cele\hum-5" "Xtro\myo1h, Xtro\myo1e.1, Xtro\myo1c, Xtro\myo1f, Xtro\myo1d, Xtro\myo1a" "Mmus\Myo1h, Mmus\Myo1b, Mmus\Myo1e, Mmus\Myo1c, Mmus\Myo1g, Mmus\Myo1f, Mmus\Myo1a, Mmus\Myo1d" "Hsap\MYO1F, Hsap\MYO1D, Hsap\MYO1B, Hsap\MYO1E, Hsap\MYO1H, Hsap\MYO1A, Hsap\MYO1C, Hsap\MYO1G" viable male genitalia FBgn0033710 CG17739 - http://flybase.org/reports/FBgn0033710 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CT39321, anon-WO0153538.35, CG17739" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR002861:Reeler domain, IPR009465:Spondin, N-terminal" CG17739 11-Aug-17 DroID_v2017_08 "Drer\spon1a, Drer\spon1b, Drer\thsd7bb, Drer\thsd7ba, Drer\thsd7aa" - Cele\spon-1 "Xtro\thsd7a, Xtro\thsd7b, Xtro\spon1" "Mmus\Thsd7b, Mmus\Reln, Mmus\Spon1, Mmus\Thsd7a, Mmus\Spon2" "Hsap\SPON1, Hsap\RELN, Hsap\THSD7A, Hsap\THSD7B, Hsap\SPON2" viable FBgn0262858 CG43222 - http://flybase.org/reports/FBgn0262858 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43222, DMG4-MB6.chr3R.35.021" - CG43222 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064162 lin-10 lin-10 http://flybase.org/reports/FBgn0064162 gene - - - "Flin-10, lin-10" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054034 CG34034 - http://flybase.org/reports/FBgn0054034 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "BP1088, HDC14863, CG34034" - CG34034 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032478 CG5458 - http://flybase.org/reports/FBgn0032478 protein_coding_gene molecular_function ; GO:0003674 | no biological data available axoneme assembly ; GO:0035082 | inferred from sequence or structural similarity with HGNC:12371 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:12371 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:12371 CG5458 IPR003409:MORN motif CG5458 11-Aug-17 DroID_v2017_08 "Drer\jph3, Drer\als2b, Drer\rsph10b, Drer\rsph1, Drer\jph2, Drer\als2a, Drer\morn4, Drer\jph1b, Drer\jph1a, Drer\si:ch211-146m13.3" - - "Xtro\als2cl, Xtro\morn5, Xtro\rsph10b, Xtro\als2, Xtro\rsph1, Xtro\jph2, Xtro\jph1" "Mmus\Morn5, Mmus\Jph2, Mmus\Jph4, Mmus\Jph3, Mmus\Morn4, Mmus\Jph1, Mmus\Morn3, Mmus\Rsph1, Mmus\Morn1, Mmus\Als2, Mmus\Als2cl" "Hsap\MORN1, Hsap\JPH2, Hsap\JPH4, Hsap\JPH1, Hsap\ALS2CL, Hsap\ALS2, Hsap\MORN5, Hsap\RSPH1, Hsap\RSPH10B, Hsap\MORN4, Hsap\RSPH10B2, Hsap\JPH3, Hsap\MORN3" viable FBgn0013455 fs(2)neo12 fs(2)neo12 http://flybase.net/reports/FBgn0013455.html gene unnamed 11-Aug-17 DroID_v2017_08 "female sterile,lethal,maternal effect" FBgn0003560 Su(f)D "Suppressor of forked, Dominant" http://flybase.org/reports/FBgn0003560 - gene - - - "Su[D]-f, Su(f)D, Su(f)" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female semi-sterile" macrochaeta FBgn0039480 Cpr97Ea Cuticular protein 97Ea http://flybase.org/reports/FBgn0039480 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr97Ea, CG6131" IPR000618:Insect cuticle protein CG6131 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262943 CR43262 - http://flybase.org/reports/FBgn0262943 non_protein_coding_gene - - - CR43262 - CR43262 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027790 GV1 GV1 http://flybase.org/reports/FBgn0027790 "FBgn0035278, FBgn0061378" protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay biological_process ; GO:0008150 | no biological data available nuclear membrane ; GO:0031965 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DIP1, CG12023, BcDNA:RH49123, GV1" - CG12023 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage organism

embryonic stage organism

viable FBgn0266149 CR44855 - http://flybase.org/reports/FBgn0266149 non_protein_coding_gene - - - CR44855 - CR44855 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060413 l(3)S129803 lethal (3) S129803 http://flybase.org/reports/FBgn0060413 gene - - - "1298/03, l(3)S129803" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0264302 CG43780 - http://flybase.org/reports/FBgn0264302 protein_coding_gene - - - "CG43780, CG8600" - CG43780 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0036949 CG7290 - http://flybase.org/reports/FBgn0036949 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG7290 IPR002557:Chitin binding domain CG7290 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\R02F2.4, Cele\cpg-2, Cele\C39D10.7, Cele\cpg-1" - - Hsap\MATN2 viable FBgn0013632 l(3)neo51 lethal (3) neo51 http://flybase.org/reports/FBgn0013632 - gene - - - l(3)neo51 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0031677 CG14036 - http://flybase.org/reports/FBgn0031677 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype - CG14036 "IPR013087:Zinc finger C2H2-type, IPR022776:TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG14036 11-Aug-17 DroID_v2017_08 "Drer\zgc:56699, Drer\LOC100535654" - Cele\T06A10.3 "Xtro\gtsf1, Xtro\LOC100145274" "Mmus\BC048502, Mmus\Gtsf1l, Mmus\Gtsf1, Mmus\Zfp850" "Hsap\GTSF1L, Hsap\GTSF1" viable FBgn0065864 l(2)SH0267 lethal (2) SH0267 http://flybase.org/reports/FBgn0065864 gene - - - l(2)SH0267 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003473 sph sparse hairs http://flybase.org/reports/FBgn0003473 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(1)x-4, l(1)sph, x-4, R-9-5, 4P1, l(1)R-9-5, X-4, l(1)X-4, lX4, l4P1, 30, 27, 26, 18, l(1)S1, l(1)7-96, l(1)20Ea, sph" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,heat sensitive,lethal,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" "adult thorax & microchaeta,eye,wing,adult thorax & microchaeta | conditional ts,heat sensitive,ovariole,germline clone,egg" FBgn0002103 l(2)57Dd lethal (2) 57Dd http://flybase.org/reports/FBgn0002103 - gene - - - l(2)57Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032805 CG10337 - http://flybase.org/reports/FBgn0032805 protein_coding_gene - - - CG10337 IPR006593:Cytochrome b561/ferric reductase transmembrane CG10337 11-Aug-17 DroID_v2017_08 "Drer\cyb561d1, Drer\cyb561d2" - - - "Mmus\Cyb561d1, Mmus\Cyb561d2" "Hsap\CYB561D1, Hsap\CYB561D2" viable FBgn0027930 MP1 Melanization Protease 1 http://flybase.org/reports/FBgn0027930 - protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 melanization defense response ; GO:0035006 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model response to fungus ; GO:0009620 | inferred from expression pattern" - "CG1102, SP25, proPO-AE, BEST:GH02921, MP1" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG1102 11-Aug-17 DroID_v2017_08 - - "Cele\try-1, Cele\svh-1" - Mmus\C2 - "developmental rate defective,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,lethal,wound healing defective,viable" "melanotic mass | larval stage,melanotic mass | P-stage,melanotic mass | adult stage" FBgn0083022 snoRNA:Psi18S-640e snoRNA:Psi18S-640e http://flybase.org/reports/FBgn0083022 snoRNA_gene - - - "snoRNA:Psi18S-640e, psi18s-640e, CR34581" - CR34581 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028952 Kebab Kinetochore and EB1 associated basic protein http://flybase.org/reports/FBgn0028952 protein_coding_gene kinetochore binding ; GO:0043515 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from direct assay biological_process ; GO:0008150 | no biological data available condensed chromosome kinetochore ; GO:0000777 | colocalizes_with inferred from direct assay spindle microtubule ; GO:0005876 | colocalizes_with inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "n(2)k09932, BEST:LD15963, CG4248, Kebab, kebab, keb, CG31672" - CG31672 11-Aug-17 DroID_v2017_08 - - Cele\unc-95 - - Hsap\RHOA "viable,fertile" FBgn0259863 Su(Ste):CR42432 Su(Ste):CR42432 http://flybase.org/reports/FBgn0259863 non_protein_coding_gene - - - "Su(Ste):CR42432, CR42432" - CR42432 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051659 CG31659 - http://flybase.org/reports/FBgn0051659 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG16933, CG31659" "IPR012674:Calycin, IPR022271:Lipocalin, ApoD type" CG31659 11-Aug-17 DroID_v2017_08 "Drer\apoda.1, Drer\apoda.2, Drer\apodb" - Cele\lpr-4 - Mmus\Apod Hsap\APOD viable FBgn0003626 Su(var)314 Suppressor of variegation 314 http://flybase.org/reports/FBgn0003626 - gene - - - Su(var)314 - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,viable" FBgn0028637 ifm(2)RU5 indirect flight muscle (2) RU5 http://flybase.org/reports/FBgn0028637 gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay ifm(2)RU5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,flight defective,sterile,viable" "indirect flight muscle,indirect flight muscle & myofibril,wing,dorsal medial muscle" FBgn0011133 l(1)Q208 lethal (1) Q208 http://flybase.org/reports/FBgn0011133 FBgn0010210 gene - - - l(1)Q208 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265198 CR44258 - http://flybase.org/reports/FBgn0265198 non_protein_coding_gene - - - CR44258 - CR44258 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013656 ms(2)neo1 male sterile (2) neo1 http://flybase.org/reports/FBgn0013656 - gene - - - ms(2)neo1 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0264716 CR43984 - http://flybase.org/reports/FBgn0264716 non_protein_coding_gene - - - CR43984 - CR43984 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065153 l(3)SH064 lethal (3) SH064 http://flybase.org/reports/FBgn0065153 gene - - - "l(3)SH064, l(2)SH3 064" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000983 fs(2)HO308 female sterile (2) HO308 http://flybase.org/reports/FBgn0000983 - gene - - - "fs(2)308A, fs(2)HO308" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005416 l(1)adl5 lethal (1) adl5 http://flybase.org/reports/FBgn0005416 - gene - - - "l(1)adl-5, l(1)adl5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,short lived" FBgn0039051 CG17109 - http://flybase.org/reports/FBgn0039051 protein_coding_gene aminoacylase activity ; GO:0004046 | inferred from electronic annotation with InterPro:IPR010159 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010159 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010159 CG17109 "IPR002933:Peptidase M20, IPR010159:N-acyl-L-amino-acid amidohydrolase, IPR011650:Peptidase M20, dimerisation domain" CG17109 11-Aug-17 DroID_v2017_08 "Drer\acy1, Drer\LOC100001620, Drer\pm20d1.2, Drer\pm20d1.1" Scer\CPS1 "Cele\C06A6.4, Cele\C10C5.4, Cele\C10C5.3, Cele\C10C5.5" "Xtro\acy1.1, Xtro\pm20d1" "Mmus\Pm20d1, Mmus\Acy1, Mmus\Cndp1" "Hsap\PM20D1, Hsap\CNDP1, Hsap\ACY1, Hsap\ABHD14A, Hsap\ABHD14A-ACY1" "partially lethal - majority die,some die during pupal stage,viable" FBgn0031054 Ssu72 Ssu72 CTD phosphatase http://flybase.org/reports/FBgn0031054 protein_coding_gene CTD phosphatase activity ; GO:0008420 | inferred from direct assay phosphatase activity ; GO:0016791 | inferred from direct assay termination of RNA polymerase II transcription ; GO:0006369 | inferred from biological aspect of ancestor with PANTHER:PTN000463875 mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000463875 protein dephosphorylation ; GO:0006470 | inferred from direct assay dephosphorylation of RNA polymerase II C-terminal domain ; GO:0070940 | inferred from direct assay mRNA 3'-end processing ; GO:0031124 | inferred from sequence or structural similarity with SGD:S000005166 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005166 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000463875 "BEST:CK01830, CG14216, Ssu72, dSsu72" IPR006811:RNA polymerase II subunit A CG14216 11-Aug-17 DroID_v2017_08 Drer\ssu72 Scer\SSU72 Cele\ssup-72 Xtro\ssu72 Mmus\Ssu72 Hsap\SSU72 "viable,visible,lethal,recessive" trichogen cell FBgn0001709 l(1)ESHS30 lethal (1) ESHS30 http://flybase.org/reports/FBgn0001709 - gene - - - l(1)ESHS30 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086168 E(var)2-1 Enhancer of variegation 2-1 http://flybase.org/reports/FBgn0086168 gene - - - E(var)2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0083036 snoRNA:Psi18S-525c snoRNA:Psi18S-525c http://flybase.org/reports/FBgn0083036 snoRNA_gene - - - "snoRNA:Psi18S-525c, psi18S-525c, CR34573" - CR34573 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038602 CG7126 - http://flybase.org/reports/FBgn0038602 protein_coding_gene - - - CG7126 - CG7126 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0277428 l(3)psg29 - http://flybase.org/reports/FBgn0277428 gene - - - "l(3)psg29, psg29" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030242 sofe sister of feo http://flybase.org/reports/FBgn0030242 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR007145 signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR015898 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR015898 microtubule cytoskeleton organization ; GO:0000226 | inferred from electronic annotation with InterPro:IPR007145 cytokinesis ; GO:0000910 | inferred from electronic annotation with InterPro:IPR007145 heterotrimeric G-protein complex ; GO:0005834 | inferred from electronic annotation with InterPro:IPR015898 "CG1655, sofe" "IPR007145:Microtubule-associated protein, MAP65/Ase1/PRC1, IPR015898:G-protein gamma-like domain" CG1655 11-Aug-17 DroID_v2017_08 "Drer\zgc:86764, Drer\prc1a, Drer\prc1b" Scer\ASE1 Cele\spd-1 "Xtro\prc1.2, Xtro\jakmip3, Xtro\prc1" Mmus\Prc1 Hsap\PRC1 "viable,fertile" FBgn0262631 CR43148 - http://flybase.org/reports/FBgn0262631 non_protein_coding_gene - - - CR43148 - CR43148 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050122 CG30122 - http://flybase.org/reports/FBgn0050122 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "LD11002, CG18610, CG5477, CG30122, SAF-A" "IPR003034:SAP domain, IPR003877:SPRY domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001870:B30.2/SPRY domain" CG30122 11-Aug-17 DroID_v2017_08 "Drer\hnrnpul1l, Drer\hnrnpub, Drer\si:ch211-107m4.1, Drer\hnrnpua, Drer\hnrnpul1" - "Cele\tofu-2, Cele\Y41E3.11, Cele\acin-1" "Xtro\hnrnpul2, Xtro\hnrnpu, Xtro\rnf123, Xtro\hnrnpul1" "Mmus\Hnrnpul2, Mmus\Rnf123, Mmus\Hnrnpu, Mmus\Hnrnpul1" "Hsap\RNF123, Hsap\HNRNPUL1, Hsap\HNRNPU, Hsap\HNRNPUL2" viable FBgn0065908 l(2)SH0185 lethal (2) SH0185 http://flybase.org/reports/FBgn0065908 gene - - - "l(2)SH0185, l(2)SH2 0185" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039670 CG7567 - http://flybase.org/reports/FBgn0039670 protein_coding_gene - - - "BcDNA:RE47447, CG7567" IPR007931:Protein of unknown function DUF725 CG7567 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0020445 E23 Early gene at 23 http://flybase.org/reports/FBgn0020445 "FBgn0031524, FBgn0031525" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000443108" regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype regulation of circadian rhythm ; GO:0042752 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CG15410, CG3327, E23" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3327 11-Aug-17 DroID_v2017_08 "Drer\abcg5, Drer\abcg2b, Drer\abcg8, Drer\abcg2a, Drer\abcg4a, Drer\abcg1, Drer\abcg4b" "Scer\PDR10, Scer\ADP1, Scer\YOL075C" "Cele\wht-4, Cele\pmp-3" "Xtro\abcg8, Xtro\abcg5" "Mmus\Abcg4, Mmus\Abcd4, Mmus\Abcg3, Mmus\Abcg1, Mmus\Abcg5, Mmus\Abcg2, Mmus\Abcg8" "Hsap\ABCG8, Hsap\ABCG5, Hsap\ABCD4, Hsap\ABCG4, Hsap\ABCG1" "viable,locomotor rhythm defective,lethal,circadian rhythm defective" FBgn0021974 l(2)k09932 lethal (2) k09932 http://flybase.org/reports/FBgn0021974 - gene - - - l(2)k09932 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003159 CG2841 - http://flybase.org/reports/FBgn0003159 FBgn0029614 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "EG:BACH48C10.5, CG2841, ptr" - CG2841 11-Aug-17 DroID_v2017_08 "Drer\cobll1a, Drer\cobll1b" - - - Mmus\Cobll1 Hsap\COBLL1 viable FBgn0259741 CG42395 - http://flybase.org/reports/FBgn0259741 protein_coding_gene - - - CG42395 IPR006696:Protein of unknown function DUF423 CG42395 11-Aug-17 DroID_v2017_08 "Drer\tmem256, Drer\rps29" - "Cele\Y106G6H.8, Cele\rps-29" "Xtro\rps29, Xtro\tmem256" "Mmus\Tmem256, Mmus\Rps29" "Hsap\RPS29, Hsap\TMEM256" FBgn0027315 l(1)G0090 lethal (1) G0090 http://flybase.org/reports/FBgn0027315 - gene - - - l(1)G0090 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002161 l(2)Sp2b lethal (2) Sp2b http://flybase.org/reports/FBgn0002161 - gene - - - l(2)Sp2b - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001991 Ca-alpha1D Ca[2+]-channel protein alpha[[1]] subunit D http://flybase.org/reports/FBgn0001991 FBgn0004881 protein_coding_gene voltage-gated calcium channel activity ; GO:0005245 | inferred from mutant phenotype high voltage-gated calcium channel activity ; GO:0008331 | inferred from biological aspect of ancestor with PANTHER:PTN000004694 voltage-gated calcium channel activity ; GO:0005245 | inferred from sequence or structural similarity voltage-gated calcium channel activity ; GO:0005245 | non-traceable author statement calcium-mediated signaling ; GO:0019722 | inferred from mutant phenotype membrane depolarization during action potential ; GO:0086010 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 muscle contraction ; GO:0006936 | traceable author statement calcium ion transmembrane transport ; GO:0070588 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype epithelial fluid transport ; GO:0042045 | inferred from direct assay inferred from expression pattern calcium ion transport ; GO:0006816 | non-traceable author statement voltage-gated calcium channel complex ; GO:0005891 | non-traceable author statement voltage-gated calcium channel complex ; GO:0005891 | inferred from sequence or structural similarity apical plasma membrane ; GO:0016324 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay voltage-gated calcium channel complex ; GO:0005891 | inferred from genetic interaction with cac "Ca-alpha1D, CG4894, Dmca1D, DmCa1D, alpha1D, BG:DS02795.1, Ca-a1D, Ca-_1D, Ca-alpha1, l(2)35Fa, DmCa1alpha1, alpha1, DroCa1, l35Fa, Ca-alpha[[1]]D, Caalpha1D, ca-alpha1D, cad, Ca_alpha1D, ca-alpha1d, caID, Ca1D" "IPR002077:Voltage-dependent calcium channel, alpha-1 subunit, IPR005446:Voltage-dependent calcium channel, L-type, alpha-1 subunit, IPR005821:Ion transport domain, IPR014873:Voltage-dependent calcium channel, alpha-1 subunit, IQ domain, IPR031649:Voltage-dependent L-type calcium channel, IQ-associated domain, IPR031688:Voltage-gated calcium channel subunit alpha, C-terminal" CG4894 11-Aug-17 DroID_v2017_08 "Drer\cacna1db, Drer\scn4ab, Drer\cacna1ab, Drer\cacna1c, Drer\cacna1fb, Drer\nalcn, Drer\scn4aa, Drer\cacna1bb, Drer\cacna1aa, Drer\cacna1eb, Drer\cacna1e, Drer\cacna1fa, Drer\scn8ab, Drer\scn1a, Drer\cacna1ba, Drer\cacna1sa, Drer\cacna1da, Drer\scn1lab, Drer\cacna1sb" Scer\CCH1 "Cele\nca-2, Cele\egl-19, Cele\unc-77, Cele\unc-2" "Xtro\scn5a, Xtro\cacna1a, Xtro\cacna1d, Xtro\scn4a, Xtro\cacna1f, Xtro\scn3a, Xtro\cacna1e, Xtro\cacna1s, Xtro\nalcn" "Mmus\Catsper2, Mmus\Scn8a, Mmus\Scn5a, Mmus\Scn3a, Mmus\Cacna1e, Mmus\Scn10a, Mmus\Cacna1a, Mmus\Cacna1b, Mmus\Nalcn, Mmus\Cacna1f, Mmus\Cacna1c, Mmus\Scn9a, Mmus\Scn11a, Mmus\Cacna1d, Mmus\Cacna1s" "Hsap\SCN10A, Hsap\CACNA1F, Hsap\CACNA1S, Hsap\CACNA1A, Hsap\SCN9A, Hsap\CACNA1D, Hsap\CACNA1B, Hsap\CACNA1C, Hsap\SCN8A, Hsap\SCN5A, Hsap\SCN11A, Hsap\SCN3A, Hsap\NALCN, Hsap\CACNA1E" " adult stage , pupal stage | late , embryonic stage | 9-12 hr , embryonic stage " " adult head

, embryonic nervous system

" "lethal,recessive,wild-type,neuroanatomy defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,longitudinal connective,abdominal segmental nerve,NMJ bouton,neuromuscular junction,embryonic/larval tracheal system,embryonic/larval midgut,cephalopharyngeal skeleton,embryonic/larval dorsal vessel" FBgn0265380 CR44321 - http://flybase.org/reports/FBgn0265380 non_protein_coding_gene - - - CR44321 - CR44321 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036851 CG14082 - http://flybase.org/reports/FBgn0036851 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14082 - CG14082 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011320 l(3)j2A2 lethal (3) j2A2 http://flybase.org/reports/FBgn0011320 - gene - - - l(3)j2A2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260623 2L3328 - http://flybase.org/reports/FBgn0260623 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3328 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0261526 NT1 Neurotrophin 1 http://flybase.org/reports/FBgn0261526 protein_coding_gene growth factor activity ; GO:0008083 | inferred from mutant phenotype Toll binding ; GO:0005121 | inferred from sequence or structural similarity with spz motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype regulation of cell death ; GO:0010941 | inferred from direct assay Toll signaling pathway ; GO:0008063 | inferred from sequence or structural similarity with spz central nervous system formation ; GO:0021556 | inferred from mutant phenotype regulation of neuronal synaptic plasticity in response to neurotrophin ; GO:0031637 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence or structural similarity with spz "NT1, dNT1, Spz2, CG18318, DNT1, CT30097, spz2, CG42576, CG32242, CG32244, Spz-2" "IPR029034:Cystine-knot cytokine, IPR032104:Spaetzle" CG42576 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028620 l(2)10565a lethal (2) 10565a http://flybase.org/reports/FBgn0028620 gene - - - "l(2)10565, l(2)10565a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262516 Trpml "Transient receptor potential cation channel, mucolipin" http://flybase.org/reports/FBgn0262516 protein_coding_gene "calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with pyx cation channel activity ; GO:0005261 | inferred from direct assay intracellular ligand-gated ion channel activity ; GO:0005217 | inferred from direct assay phosphatidylinositol-3,5-bisphosphate binding ; GO:0080025 | inferred from direct assay" lateral inhibition ; GO:0046331 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype negative regulation of growth of symbiont in host ; GO:0044130 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity cellular calcium ion homeostasis ; GO:0006874 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from sequence or structural similarity with pyx positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from direct assay cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with pyx late endosome ; GO:0005770 | inferred from direct assay endolysosome membrane ; GO:0036020 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "trpml, CT25240, CG8743, l(3)76BDi, DmTRPML, TRPML, Trpml" "IPR013122:Polycystin cation channel, PKD1/PKD2" CG8743 11-Aug-17 DroID_v2017_08 "Drer\mcoln1a, Drer\mcoln3b, Drer\mcoln3a, Drer\mcoln2, Drer\mcoln1b" - Cele\cup-5 "Xtro\mcoln2, Xtro\LOC101734792, Xtro\mcoln3, Xtro\mcoln1" "Mmus\Mcoln3, Mmus\Mcoln2, Mmus\Mcoln1" "Hsap\MCOLN1, Hsap\MCOLN2, Hsap\MCOLN3" DRSC11032 I -1.633237991 -0.323258828 0.189626555 -0.17759202 0.022775855 -0.333471541 FBgn0044345 scratch-like2 scratch-like2 http://flybase.org/reports/FBgn0044345 gene - - - scratch-like2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051528 CG31528 - http://flybase.org/reports/FBgn0051528 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH26112, BcDNA:GH26112, CG31528" "IPR000626:Ubiquitin domain, IPR015940:Ubiquitin-associated domain, IPR015496:Ubiquilin, IPR029071:Ubiquitin-related domain, IPR009060:UBA-like" CG31528 11-Aug-17 DroID_v2017_08 Drer\ubqln4 Scer\DSK2 "Cele\F49C12.9, Cele\ubql-1" "Xtro\ubqln1, Xtro\ubqln4" "Mmus\4931431F19Rik, Mmus\Ubqln2, Mmus\Ubqln1, Mmus\Ubqlnl, Mmus\Ubqln4, Mmus\Ubqln3" "Hsap\UBQLN1, Hsap\UBQLN4, Hsap\UBQLN2, Hsap\UBQLN3, Hsap\UBQLNL" viable FBgn0267728 otk2 off-track2 http://flybase.org/reports/FBgn0267728 protein_coding_gene "coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway ; GO:1904929 | inferred from electronic annotation with InterPro:IPR033592 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with otk protein homodimerization activity ; GO:0042803 | inferred from physical interaction with otk2 Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt2" Wnt signaling pathway ; GO:0016055 | inferred from electronic annotation with InterPro:IPR033592 convergent extension ; GO:0060026 | inferred from electronic annotation with InterPro:IPR033592 establishment of planar polarity ; GO:0001736 | inferred from electronic annotation with InterPro:IPR033592 imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from genetic interaction with otk imaginal disc-derived female genitalia morphogenesis ; GO:0048804 | inferred from genetic interaction with otk internal genitalia morphogenesis ; GO:0035260 | inferred from genetic interaction with otk integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR033592 integral component of membrane ; GO:0016021 | inferred from sequence model "otk2, CG8964, CT25760, l(2)SH1639, l(2)SH2 1639" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR033592:Inactive tyrosine-protein kinase 7, IPR013106:Immunoglobulin V-set domain" CG8964 11-Aug-17 DroID_v2017_08 "Drer\vwa10.2, Drer\LOC100006752, Drer\LOC101884775, Drer\vwa11, Drer\si:ch73-380l3.2, Drer\zmp:0000001289, Drer\sc:d0284, Drer\si:dkey-14o18.6, Drer\si:ch211-286b5.9, Drer\si:ch211-1f22.3, Drer\LOC100535144, Drer\LOC100148735, Drer\zgc:172106, Drer\vwa7, Drer\spegb, Drer\scospondin, Drer\LOC100333105, Drer\hmcn2, Drer\ttnb, Drer\zgc:171470, Drer\cd22, Drer\LOC100333244, Drer\zmp:0000000971, Drer\si:ch211-171h4.5, Drer\vwa10.1, Drer\ptk7a, Drer\LOC101885775, Drer\ptk7b" - Cele\igcm-4 "Xtro\ceacam8, Xtro\MGC89178, Xtro\hmcn2, Xtro\ptk7" "Mmus\Hmcn2, Mmus\Hmcn1, Mmus\Vwa7, Mmus\Obscn, Mmus\Ptk7" "Hsap\SIGLEC15, Hsap\OBSCN, Hsap\PTK7, Hsap\VWA7, Hsap\HMCN1" FBgn0062646 EP531 EP531 http://flybase.org/reports/FBgn0062646 gene - - - "EP(2)0531, EP531" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038746 Surf6 Surfeit 6 http://flybase.org/reports/FBgn0038746 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with MGI:MGI:98447 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 ventral cord development ; GO:0007419 | inferred from mutant phenotype ribosomal small subunit biogenesis ; GO:0042274 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 ribosome biogenesis ; GO:0042254 | inferred from sequence or structural similarity with MGI:MGI:98447 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with MGI:MGI:98447 cytosolic large ribosomal subunit ; GO:0022625 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 "CG4510, Surf6" "IPR007019:Surfeit locus 6, IPR029190:Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain" CG4510 11-Aug-17 DroID_v2017_08 Drer\surf6 Scer\RRP14 Cele\ZK546.14 Xtro\surf6 Mmus\Surf6 Hsap\SURF6 "viable,fertile,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0011140 l(1)Q216 lethal (1) Q216 http://flybase.org/reports/FBgn0011140 FBgn0010210 gene - - - l(1)Q216 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005669 e(mr) enhancer of morula http://flybase.org/reports/FBgn0005669 - gene - - - e(mr) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024691 fsf fruitless stimulation factor http://flybase.org/reports/FBgn0024691 - gene - - - fsf - - 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,male" FBgn0261975 CG42806 - http://flybase.org/reports/FBgn0261975 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42806 - CG42806 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265341 CR44295 - http://flybase.org/reports/FBgn0265341 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44295, CR44295" - CR44295 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032205 CG4957 - http://flybase.org/reports/FBgn0032205 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000283242 CG4957 "IPR002876:Transcriptional regulator TACO1-like, IPR017856:Integrase, N-terminal zinc-binding domain-like, IPR029072:YebC-like, IPR026564:Transcriptional regulator TACO1-like, domain 3" CG4957 11-Aug-17 DroID_v2017_08 "Drer\LOC100534805, Drer\taco1" Scer\YGR021W Cele\taco-1 Xtro\taco1 Mmus\Taco1 Hsap\TACO1 viable FBgn0025475 prd::Mmus\Pax8 Pax8 http://flybase.org/reports/FBgn0025475 - engineered_fusion_gene - - - prd::Mmus\Pax8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264794 CR44024 - http://flybase.org/reports/FBgn0264794 non_protein_coding_gene - - - CR44024 - CR44024 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012001 tRNA:Val-CAC-2-4 transfer RNA:Valine-CAC 2-4 http://flybase.org/reports/FBgn0012001 "FBgn0003853, FBgn0011997, FBgn0051502, FBgn0060026" tRNA_gene GUG codon-amino acid adaptor activity ; GO:0033452 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033452 cytosol ; GO:0005829 | inferred by curator from GO:0033452 "CR31502, valine tRNA, tRNA[Val][[3b]], Val-3b, AE002699.trna1-ValCAC, tRNA:V3b, tRNA:V:CAC:AE002699-a, tRNA:val3b:84Dd, chr3R.trna74-ValCAC, tRNA:Val-CAC-2-4, tRNA:V3b:84Dd, tRNA-Val-CAC-2-4, GUG" - CR31502 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002385 l(3)93Da lethal (3) 93Da http://flybase.org/reports/FBgn0002385 - gene - - - "er1, l(3)er1, l(3)93Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially" FBgn0052114 CG32114 - http://flybase.org/reports/FBgn0052114 protein_coding_gene - - - CG32114 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265644 CR44451 - http://flybase.org/reports/FBgn0265644 non_protein_coding_gene - - - "CR44451, lincRNA.275" - CR44451 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039402 Vps2 Vacuolar protein sorting 2 http://flybase.org/reports/FBgn0039402 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vacuolar transport ; GO:0007034 | inferred from electronic annotation with InterPro:IPR005024 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype multivesicular body ; GO:0005771 | colocalizes_with inferred from direct assay early endosome ; GO:0005769 | colocalizes_with inferred from direct assay ESCRT III complex ; GO:0000815 | inferred from sequence or structural similarity with SGD:S000004409 "NEST:bs02f06, Vps2, Did4, vps2, CG14542, dvps2, DmVPS2, Dvps2" IPR005024:Snf7 family CG14542 11-Aug-17 DroID_v2017_08 Drer\bc2 Scer\DID4 Cele\vps-2 Xtro\chmp2a Mmus\Chmp2a Hsap\CHMP2A "lethal,lethal - all die before end of embryonic stage,hypoplasia,somatic clone,hyperplasia,somatic clone - Minute background,increased cell death" "embryonic/larval brain,wing disc,somatic clone,somatic clone - Minute background,haltere disc,ventral thoracic disc,epithelium,epithelial cell,actin cytoskeleton | somatic clone - Minute background | third instar larval stage,nucleus | somatic clone - Minute background | third instar larval stage,eye,egg chamber,plasma membrane | somatic clone" DRSC14886 K 0.243924232 -0.808890626 0.86566227 -0.834529864 -2.064803496 -1.4775397 FBgn0266536 CR45097 - http://flybase.org/reports/FBgn0266536 non_protein_coding_gene - - - CR45097 - CR45097 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065176 l(3)SH010 lethal (3) SH010 http://flybase.org/reports/FBgn0065176 gene - - - "l(3)SH010, l(2)SH3 010" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005014 dipp-5 defective in phototaxis plasticity 5 http://flybase.org/reports/FBgn0005014 - gene - - - dipp-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,visual behavior defective,phototaxis defective" FBgn0034901 CG11300 - http://flybase.org/reports/FBgn0034901 protein_coding_gene - - - "BcDNA:LP08443, CG11300" - CG11300 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020647 KrT95D Krueppel target at 95D http://flybase.org/reports/FBgn0020647 - protein_coding_gene - protein targeting to plasma membrane ; GO:0072661 | inferred from biological aspect of ancestor with PANTHER:PTN000998635 - "CG5405, KrT95D" IPR019381:Phosphofurin acidic cluster sorting protein 1 CG5405 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-126j24.1, Drer\pacs2, Drer\pacs1a" - Cele\tag-232 "Xtro\pacs2, Xtro\pacs1" "Mmus\Pacs2, Mmus\Pacs1" "Hsap\PACS1, Hsap\PACS2" "viable,fertile,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0052710 CG32710 - http://flybase.org/reports/FBgn0052710 protein_coding_gene - - - CG32710 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053189 CG33189 - http://flybase.org/reports/FBgn0053189 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33189 - CG33189 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015282 Rpt2 Regulatory particle triple-A ATPase 2 http://flybase.org/reports/FBgn0015282 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | inferred from sequence model TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 "proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9547 inferred from direct assay nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000002165 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from direct assay" "pros26.4, S4, p56, dRpt2, Dm_Rpt2, DmP26S4, P26s4, CG5289, Pros26.4, Dm-S4-1, PSMC1, Rpt2, 5289" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5289 11-Aug-17 DroID_v2017_08 "Drer\psmc1a, Drer\psmc1b" Scer\RPT2 "Cele\C10G11.8, Cele\rpt-2" Xtro\psmc1 Mmus\Psmc1 Hsap\PSMC1 "meiotic cell cycle defective,male limited,lethal" "testis,spermatocyte" DRSC16799 IEK -2.739142906 -5.993688164 -2.727832802 -4.097045764 4.025543552 3.135853425 FBgn0063414 l(3)3450-I lethal (3) 3450-I http://flybase.org/reports/FBgn0063414 gene - - - l(3)3450-I - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031454 CG9960 - http://flybase.org/reports/FBgn0031454 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002052 S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from biological aspect of ancestor with PANTHER:PTN000430779 protein methyltransferase activity ; GO:0008276 | inferred from biological aspect of ancestor with PANTHER:PTN000430810 methylation ; GO:0032259 | inferred from electronic annotation with InterPro:IPR002052 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000430779 "CG32951, CG9960, Dromel_CG9960_CG9958_FBtr007773_snapin_mORF, DAMT, damt" "IPR002052:DNA methylase, N-6 adenine-specific, conserved site, IPR004557:Eukaryotic/archaeal PrmC-related, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR007848:Methyltransferase small domain" CG9960 11-Aug-17 DroID_v2017_08 Drer\n6amt1 "Scer\MTQ1, Scer\MTQ2" Cele\mtq-2 Xtro\n6amt1 "Mmus\Hemk1, Mmus\N6amt1" "Hsap\HEMK1, Hsap\N6AMT1" "lethal - all die before end of pupal stage,some die during pupal stage,neurophysiology defective" FBgn0011485 l(3)neo55 lethal (3) neo55 http://flybase.org/reports/FBgn0011485 - gene - - - l(3)neo55 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030506 Lig4 Ligase4 http://flybase.org/reports/FBgn0030506 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000977, InterPro:IPR012310, InterPro:IPR029710 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR012308, InterPro:IPR029710 protein binding ; GO:0005515 | inferred from physical interaction with XRCC4 DNA ligase (ATP) activity ; GO:0003910 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 DNA ligase (ATP) activity ; GO:0003910 | inferred from sequence or structural similarity with HGNC:6601 inferred from sequence or structural similarity with SGD:S000005531" "DNA biosynthetic process ; GO:0071897 | inferred from electronic annotation with InterPro:IPR000977 DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR000977, InterPro:IPR012308, InterPro:IPR012309, InterPro:IPR012310 DNA ligation involved in DNA repair ; GO:0051103 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 telomere maintenance ; GO:0000723 | inferred from genetic interaction with tefu double-strand break repair via nonhomologous end joining ; GO:0006303 | inferred from mutant phenotype nucleotide-excision repair, DNA gap filling ; GO:0006297 | inferred from biological aspect of ancestor with PANTHER:PTN000048698 response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 DNA ligase IV complex ; GO:0032807 | inferred from biological aspect of ancestor with PANTHER:PTN000048698 DNA-dependent protein kinase-DNA ligase 4 complex ; GO:0005958 | inferred from biological aspect of ancestor with PANTHER:PTN000825456 "lig4, RE37186, CG12176, Lig4, ligIV, ligaseIV" "IPR000977:DNA ligase, ATP-dependent, IPR001357:BRCT domain, IPR012309:DNA ligase, ATP-dependent, C-terminal, IPR012310:DNA ligase, ATP-dependent, central, IPR012340:Nucleic acid-binding, OB-fold, IPR029710:DNA ligase 4, IPR012308:DNA ligase, ATP-dependent, N-terminal" CG12176 11-Aug-17 DroID_v2017_08 Drer\lig4 Scer\DNL4 "Cele\K07C5.3, Cele\Y73B6BL.14, Cele\lig-4" Xtro\lig4 Mmus\Lig4 Hsap\LIG4 "radiation sensitive,viable,fertile,rescuable maternal effect" FBgn0037177 CG14454 - http://flybase.org/reports/FBgn0037177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT34135, BcDNA:RE01153, CG14454" - CG14454 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050096 CG30096 - http://flybase.org/reports/FBgn0050096 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30096 - CG30096 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC21744 K 0.241655209 -0.122638804 -0.138504805 -0.712918551 1.889958821 0.966306003 FBgn0001698 l(1)ESHS19 lethal (1) ESHS19 http://flybase.org/reports/FBgn0001698 - gene - - - l(1)ESHS19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267076 CR45520 - http://flybase.org/reports/FBgn0267076 non_protein_coding_gene - - - CR45520 - CR45520 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032023 CG14274 - http://flybase.org/reports/FBgn0032023 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG14274 - CG14274 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0062574 Mod(var)E1261 Mod(var)E1261 http://flybase.org/reports/FBgn0062574 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1261, Mod(var)E1261" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,partially lethal - majority die" FBgn0053397 5SrRNA:CR33397 5SrRNA:CR33397 http://flybase.org/reports/FBgn0053397 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33397, 5SrRNA:CR33397" - CR33397 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259995 CG40169 - http://flybase.org/reports/FBgn0259995 protein_coding_gene - - - "anon-38C.20, CG40169, 38C.20" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC01766 I -1.530770784 0.787159639 -0.355660539 0.129055649 -1.191664174 -0.781883301 FBgn0030334 Karl Karl http://flybase.org/reports/FBgn0030334 protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG4139, Karl, karl" IPR012674:Calycin CG4139 11-Aug-17 DroID_v2017_08 "Drer\apoda.1, Drer\apodb, Drer\apoda.2" - Cele\lpr-4 - Mmus\Apod Hsap\APOD viable FBgn0267756 CR46087 - http://flybase.org/reports/FBgn0267756 non_protein_coding_gene - - - "CR46087, lincRNA.874" - CR46087 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036423 CG3919 - http://flybase.org/reports/FBgn0036423 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - - CG3919 "IPR004210:BESS motif, IPR006578:MADF domain" CG3919 11-Aug-17 DroID_v2017_08 "Drer\LOC100330838, Drer\zgc:152938, Drer\si:ch211-207i20.3" - "Cele\madf-10, Cele\madf-4, Cele\madf-9, Cele\madf-5, Cele\madf-8, Cele\madf-2, Cele\madf-3" - - - viable FBgn0035707 CG8368 - http://flybase.org/reports/FBgn0035707 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 - - CG8368 "IPR012337:Ribonuclease H-like domain, IPR013520:Exonuclease, RNase T/DNA polymerase III" CG8368 11-Aug-17 DroID_v2017_08 "Drer\zgc:152968, Drer\rexo1, Drer\rexo4, Drer\isg20" "Scer\REX3, Scer\RNH70" Cele\C05C8.5 "Xtro\rexo4, Xtro\LOC100036702, Xtro\rexo1, Xtro\LOC100158551" "Mmus\Rexo1, Mmus\Rexo4, Mmus\Isg20, Mmus\2610020H08Rik" "Hsap\LOC81691, Hsap\LOC101929627, Hsap\REXO4, Hsap\ISG20, Hsap\REXO1" viable FBgn0039915 Gat GABA transporter http://flybase.org/reports/FBgn0039915 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 gamma-aminobutyric acid:sodium symporter activity ; GO:0005332 | inferred from sequence model gamma-aminobutyric acid:sodium symporter activity ; GO:0005332 | inferred from biological aspect of ancestor with PANTHER:PTN000177868 neurotransmitter transport ; GO:0006836 | inferred from electronic annotation with InterPro:IPR000175 chemical synaptic transmission ; GO:0007268 | inferred from biological aspect of ancestor with PANTHER:PTN000177868 cellular response to mechanical stimulus ; GO:0071260 | inferred from direct assay gamma-aminobutyric acid transport ; GO:0015812 | inferred from biological aspect of ancestor with PANTHER:PTN000177868 gamma-aminobutyric acid import ; GO:0051939 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay glial cell projection ; GO:0097386 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN000177868 "anon-WO0149848.11, CG1732, CG1732a, DmGAT, CG6218, dGAT, GAT, Gat, gat" IPR000175:Sodium:neurotransmitter symporter CG1732 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-132b12.3, Drer\slc6a1a, Drer\slc6a16b, Drer\slc6a11a, Drer\slc6a19a.2, Drer\slc6a13l, Drer\si:ch211-132b12.6, Drer\slc6a16a, Drer\si:ch211-132b12.2, Drer\slc6a14, Drer\slc6a15, Drer\slc6a4a, Drer\si:ch211-117c9.5, Drer\slc6a4b, Drer\slc6a1b, Drer\slc6a13, Drer\si:ch211-132b12.1, Drer\slc6a5, Drer\zgc:158427, Drer\slc6a13, Drer\slc6a19a.1, Drer\slc6a19b, Drer\slc6a6a, Drer\zgc:158225, Drer\slc6a17, Drer\slc6a8, Drer\slc6a2, Drer\slc6a18, Drer\slc6a9, Drer\slc6a1l, Drer\slc6a6b, Drer\zgc:174946" - "Cele\snf-11, Cele\snf-9, Cele\snf-3, Cele\mod-5, Cele\dat-1, Cele\snf-6" "Xtro\slc6a13, Xtro\slc6a5, Xtro\slc6a15, Xtro\slc6a14.2, Xtro\slc6a3, Xtro\slc6a17, Xtro\slc6a19, Xtro\slc6a2, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a12, Xtro\slc6a9, Xtro\slc6a8, Xtro\slc6a7, Xtro\slc6a16, Xtro\LOC100127682, Xtro\slc6a1" "Mmus\Slc6a20b, Mmus\Slc6a12, Mmus\Slc6a2, Mmus\Slc6a3, Mmus\Slc6a15, Mmus\Slc6a20a, Mmus\Slc6a16, Mmus\Slc6a17, Mmus\Slc6a11, Mmus\Slc6a14, Mmus\Slc6a19, Mmus\Slc6a8, Mmus\Slc6a5, Mmus\Slc6a9, Mmus\Slc6a18, Mmus\Slc6a4, Mmus\Slc6a7, Mmus\Slc6a6, Mmus\Slc6a21, Mmus\Slc6a1, Mmus\Slc6a13" "Hsap\SLC6A16, Hsap\SLC6A4, Hsap\SLC6A13, Hsap\SLC6A2, Hsap\SLC6A18, Hsap\SLC6A5, Hsap\SLC6A15, Hsap\SLC6A3, Hsap\SLC6A19, Hsap\SLC6A9, Hsap\SLC6A7, Hsap\SLC6A8, Hsap\SLC6A11, Hsap\SLC6A1, Hsap\SLC6A14, Hsap\SLC6A6, Hsap\SLC6A20, Hsap\SLC6A17, Hsap\SLC6A12" viable FBgn0262104 CG42857 - http://flybase.org/reports/FBgn0262104 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42857, DMG6-MB6.chr3R.10.010" - CG42857 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053740 snmRNA:430:CR33740 snmRNA:430:CR33740 http://flybase.org/reports/FBgn0053740 non_protein_coding_gene - - - "CR33740, snmRNA:430:CR33740" - CR33740 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053977 CG33977 - http://flybase.org/reports/FBgn0053977 protein_coding_gene dolichyl-phosphate beta-D-mannosyltransferase activity ; GO:0004582 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000419487 protein O-linked mannosylation ; GO:0035269 | inferred from biological aspect of ancestor with PANTHER:PTN000419487 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000419487 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with HGNC:3007 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000419487 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:3007 dolichol-phosphate-mannose synthase complex ; GO:0033185 | inferred from biological aspect of ancestor with PANTHER:PTN000419487 CG33977 IPR013174:Dolichol-phosphate mannosyltransferase subunit 3 CG33977 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\F49E11.8, Cele\fbxa-76, Cele\C24H12.1, Cele\T27A1.3, Cele\dpm-3" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 FBgn0053777 CG33777 - http://flybase.org/reports/FBgn0053777 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33777 IPR010512:Protein of unknown function DUF1091 CG33777 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0085774 CR40779 - http://flybase.org/reports/FBgn0085774 rRNA_gene - - - CR40779 - CR40779 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063508 En(tc) Enhancer of terminal conversion http://flybase.org/reports/FBgn0063508 gene - - - En(tc) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034432 CG7461 - http://flybase.org/reports/FBgn0034432 protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091, InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786" microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG7461, cg7461" "IPR006089:Acyl-CoA dehydrogenase, conserved site, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal" CG7461 11-Aug-17 DroID_v2017_08 "Drer\acad8, Drer\acadm, Drer\acad9, Drer\acadvl, Drer\acads" - "Cele\acdh-9, Cele\acdh-7, Cele\acdh-4, Cele\acdh-1, Cele\acdh-8, Cele\acdh-12" "Xtro\acad8, Xtro\acadsb, Xtro\ivd, Xtro\MGC107841, Xtro\acad9, Xtro\acadm, Xtro\acads" "Mmus\Acadm, Mmus\Acad8, Mmus\Acadvl, Mmus\Acad9, Mmus\Acadsb, Mmus\Ivd, Mmus\Acads" "Hsap\ACADSB, Hsap\IVD, Hsap\ACADS, Hsap\ACAD9, Hsap\ACADM, Hsap\ACADVL, Hsap\ACAD8" "viable,fertile" FBgn0267353 BG02514 - http://flybase.org/reports/FBgn0267353 gene - - - BG02514 - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,female,male,heat stress response defective,starvation stress response defective,chemosensitive behavior defective" macrochaeta FBgn0264650 littoral littoral http://flybase.org/reports/FBgn0264650 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - littoral - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0052552 CG32552 - http://flybase.org/reports/FBgn0052552 protein_coding_gene - - - CG32552 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060756 l(3)S063913b lethal (3) S063913b http://flybase.org/reports/FBgn0060756 gene - - - "0639/13, l(3)S063913b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265725 CG44532 - http://flybase.org/reports/FBgn0265725 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lincRNA.970, CG44532" - CG44532 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025744 maz matzerath http://flybase.org/reports/FBgn0025744 - gene - - - maz - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant,viable" "central nervous system,wing vein,ectopic" FBgn0030804 CG13002 - http://flybase.org/reports/FBgn0030804 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13002 "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG13002 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0261634 CG42717 - http://flybase.org/reports/FBgn0261634 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG42717, HDC10387, DMG4-MB6.chr3L.27.007, DMG4-MB6.chr3L.27.007-MIP19202" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42717 11-Aug-17 DroID_v2017_08 - - "Cele\bli-5, Cele\C10G8.2" - "Mmus\Wfdc6a, Mmus\Eppin, Mmus\Wfdc6b" "Hsap\EPPIN-WFDC6, Hsap\EPPIN" FBgn0004943 agl angle winglike http://flybase.org/reports/FBgn0004943 - gene - - - agl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0030968 CG7322 - http://flybase.org/reports/FBgn0030968 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - CG7322 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG7322 11-Aug-17 DroID_v2017_08 "Drer\dcxr, Drer\zgc:101858" "Scer\AYR1, Scer\SPS19, Scer\YIR035C, Scer\IRC24" "Cele\dhs-21, Cele\T25G12.13, Cele\Y47G6A.22" "Xtro\dcxr, Xtro\MGC79752" "Mmus\Cbr2, Mmus\Dcxr" Hsap\DCXR viable FBgn0266842 CR45304 - http://flybase.org/reports/FBgn0266842 non_protein_coding_gene - - - CR45304 - CR45304 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037489 CG1234 - http://flybase.org/reports/FBgn0037489 protein_coding_gene chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000374010 - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000374010 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q07896 CG1234 "IPR005612:CCAAT-binding factor, IPR011501:Nucleolar complex-associated protein 3, N-terminal, IPR016024:Armadillo-type fold, IPR016903:Nucleolar complex-associated protein 3, IPR011989:Armadillo-like helical" CG1234 11-Aug-17 DroID_v2017_08 Drer\noc3l Scer\NOC3 Cele\C37H5.5 Xtro\noc3l Mmus\Noc3l Hsap\NOC3L "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0259748 CG42397 - http://flybase.org/reports/FBgn0259748 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG42397 IPR002557:Chitin binding domain CG42397 11-Aug-17 DroID_v2017_08 - - "Cele\cpg-1, Cele\C39D10.7, Cele\R02F2.4, Cele\cpg-2" - - - FBgn0014870 Psi P-element somatic inhibitor http://flybase.org/reports/FBgn0014870 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P17133 mRNA binding ; GO:0003729 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR015096 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype negative regulation of mRNA splicing, via spliceosome ; GO:0048025 | inferred from direct assay negative regulation of mRNA splicing, via spliceosome ; GO:0048025 | inferred from mutant phenotype mRNA processing ; GO:0006397 | inferred from direct assay regulation of mRNA splicing, via spliceosome ; GO:0048024 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay U1 snRNP ; GO:0005685 | colocalizes_with inferred from physical interaction with snRNP-U1-70K "PSI, EG:EG0003.2, CG8912, Psi" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR015096:Far upstream element-binding protein, C-terminal" CG8912 11-Aug-17 DroID_v2017_08 "Drer\fubp1, Drer\fubp3, Drer\khsrp" - "Cele\M01A10.1, Cele\C12D8.1, Cele\tofu-7, Cele\C36E6.1, Cele\ZK418.9" "Xtro\fubp3, Xtro\fubp1, Xtro\khsrp" "Mmus\Fubp3, Mmus\Khsrp, Mmus\Fubp1" "Hsap\FUBP1, Hsap\FUBP3, Hsap\KHSRP" " embryonic stage | early , embryonic stage -- adult stage , oogenesis stage && adult stage | female , embryonic stage | 2-8 hr " ovary

"wild-type,courtship behavior defective,mating defective,sterile,male,meiotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,visible" "spermatid,onion stage spermatid,testis,trichogen cell" DRSC07519 I -1.171608483 1.756830099 0.162208376 0.304035022 -0.703060183 -0.937862654 FBgn0267303 CR45739 - http://flybase.org/reports/FBgn0267303 non_protein_coding_gene - - - CR45739 - CR45739 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085515 CG40758 - http://flybase.org/reports/FBgn0085515 protein_coding_gene - - - CG40758 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265065 CR44176 - http://flybase.org/reports/FBgn0265065 non_protein_coding_gene - - - CR44176 - CR44176 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036337 AdenoK Adenosine Kinase http://flybase.org/reports/FBgn0036337 protein_coding_gene adenosine kinase activity ; GO:0004001 | inferred from biological aspect of ancestor with PANTHER:PTN000062161 adenosine kinase activity ; GO:0004001 | inferred from sequence or structural similarity with MGI:MGI:87930 adenosine salvage ; GO:0006169 | inferred from biological aspect of ancestor with PANTHER:PTN000062161 AMP biosynthetic process ; GO:0006167 | inferred from sequence or structural similarity with MGI:MGI:87930 nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG11255, DmAdk2, AdenoK" "IPR001805:Adenosine kinase, IPR002173:Carbohydrate/puine kinase, PfkB, conserved site, IPR011611:Carbohydrate kinase PfkB, IPR029056:Ribokinase-like" CG11255 11-Aug-17 DroID_v2017_08 "Drer\rbm4.2, Drer\zgc:77262, Drer\adkb, Drer\adka" Scer\ADO1 Cele\R07H5.8 Xtro\adk Mmus\Adk Hsap\ADK "viable,fertile,long lived" FBgn0060832 l(3)S050115b lethal (3) S050115b http://flybase.org/reports/FBgn0060832 gene - - - "0501/15, l(3)S050115b, l(3)s050115" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0014047 Su(tor)2-191 Su(tor)2-191 http://flybase.org/reports/FBgn0014047 - gene - - - Su(tor)2-191 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264520 ff4 - http://flybase.org/reports/FBgn0264520 gene - - - ff4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,mitotic cell cycle defective" spermatid FBgn0084352 l(3)S012805 l(3)S012805 http://flybase.org/reports/FBgn0084352 gene - - - l(3)S012805 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024621 meso2 meso2 http://flybase.org/reports/FBgn0024621 FBgn0024481 gene - - - "Clone2, meso2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032434 CG5421 - http://flybase.org/reports/FBgn0032434 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR008388 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | inferred from electronic annotation with InterPro:IPR008388" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008388 "proton-transporting V-type ATPase, V1 domain ; GO:0033180 | inferred from electronic annotation with InterPro:IPR008388" CG5421 "IPR008388:ATPase, V1 complex, subunit S1" CG5421 11-Aug-17 DroID_v2017_08 "Drer\atp6ap1la, Drer\atp6ap1a, Drer\atp6ap1lb, Drer\atp6ap1b" - Cele\vha-19 Xtro\atp6ap1.2 "Mmus\Atp6ap1l, Mmus\Atp6ap1" "Hsap\ATP6AP1, Hsap\ATP6AP1L" FBgn0001065 fs(3)T female sterile of Tabriz http://flybase.org/reports/FBgn0001065 - gene - - - fs(3)T - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,eye color defective" "female reproductive system,pigment cell" FBgn0038861 CG7009 - http://flybase.org/reports/FBgn0038861 protein_coding_gene tRNA methyltransferase activity ; GO:0008175 | inferred from electronic annotation with InterPro:IPR028590 RNA methylation ; GO:0001510 | inferred from electronic annotation with InterPro:IPR015507 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR028590 - CG7009 "IPR002877:Ribosomal RNA methyltransferase FtsJ domain, IPR015507:Ribosomal RNA large subunit methyltransferase E, IPR028590:tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG7009 11-Aug-17 DroID_v2017_08 Drer\ftsj1 Scer\TRM7 "Cele\Y40D12A.1, Cele\R74.7" Xtro\ftsj1 Mmus\Ftsj1 Hsap\FTSJ1 "viable,fertile" FBgn0083082 l(4)B6-C1 lethal (4) B6-C1 http://flybase.org/reports/FBgn0083082 gene - - - l(4)B6-C1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005739 l(1)TK229 lethal (1) TK229 http://flybase.org/reports/FBgn0005739 - gene - - - "l229, l(1)TK229" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0020294 ko knockout http://flybase.org/reports/FBgn0020294 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG10573, ko" "IPR019391:Storkhead-box protein, winged-helix domain" CG10573 11-Aug-17 DroID_v2017_08 "Drer\stox1, Drer\stox2b, Drer\stox2a" - Cele\ham-1 "Xtro\stox2, Xtro\stox1" "Mmus\Stox1, Mmus\Stox2" "Hsap\STOX1, Hsap\STOX2" "viable,fertile,neuroanatomy defective" "RP5 motor neuron,RP3 motor neuron" FBgn0064237 Idgf5 Imaginal disc growth factor 5 http://flybase.org/reports/FBgn0064237 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 imaginal disc growth factor receptor binding ; GO:0008084 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from direct assay" extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "CG5154, IDGF-5, IDGF5, Idgf5, IDGF, Cht14, DmIDGF5, idgf5" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG5154 11-Aug-17 DroID_v2017_08 "Drer\chia.4, Drer\chia.3, Drer\ovgp1, Drer\si:ch211-226m16.2, Drer\chia.6, Drer\chia.5, Drer\chia.2" Scer\CTS2 "Cele\chil-23, Cele\chil-24, Cele\chil-20, Cele\chil-25, Cele\cht-2, Cele\chil-11, Cele\chil-16, Cele\chil-17, Cele\chil-19, Cele\T19H5.6, Cele\chil-5, Cele\chil-15, Cele\lmd-4, Cele\chil-6, Cele\lmd-5, Cele\chil-7, Cele\chil-8, Cele\chil-18, Cele\chil-12, Cele\chil-22, Cele\chil-3, Cele\chil-4, Cele\chil-2, Cele\chil-13" "Xtro\chia, Xtro\LOC548945, Xtro\ctbs, Xtro\chit1" "Mmus\Chil4, Mmus\Ctbs, Mmus\Chit1, Mmus\Chil6, Mmus\Chil3, Mmus\Chil5, Mmus\Ovgp1, Mmus\Chia1, Mmus\Chil1" "Hsap\CHI3L2, Hsap\OVGP1, Hsap\CHIT1, Hsap\CHIA, Hsap\CHI3L1" viable FBgn0030339 Cyp28c1 Cyp28c1 http://flybase.org/reports/FBgn0030339 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "28c1, CG1895, Cyp28c1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG1895 11-Aug-17 DroID_v2017_08 "Drer\cyp3c3, Drer\cyp19a1b, Drer\cyp26b1, Drer\cyp46a1.4, Drer\cyp4f3, Drer\cyp3c2, Drer\cyp26c1, Drer\LOC100329425, Drer\cyp3a65, Drer\cyp4v7, Drer\cyp46a1.1, Drer\cyp46a1.3, Drer\cyp4v8, Drer\cyp19a1a, Drer\cyp26a1, Drer\cyp3c1, Drer\cyp20a1, Drer\tbxas1, Drer\cyp3c4, Drer\cyp46a1.2, Drer\cyp4t8" "Scer\ERG11, Scer\ERG5, Scer\DIT2" "Cele\cyp-25A6, Cele\cyp-13A12, Cele\cyp-25A3, Cele\cyp-13A2, Cele\cyp-13A6, Cele\cyp-13A5, Cele\cyp-13A10, Cele\cyp-13B2, Cele\cyp-13A11, Cele\cyp-13A4, Cele\cyp-44A1, Cele\cyp-25A2, Cele\cyp-13A7, Cele\cyp-25A4, Cele\cyp-13A3, Cele\cyp-13A1, Cele\cyp-43A1, Cele\cyp-13B1, Cele\cyp-25A1, Cele\cyp-13A8" "Xtro\mgc108213, Xtro\cyp3a4, Xtro\cyp19a1, Xtro\cyp4b1, Xtro\LOC100494419, Xtro\cyp4f2, Xtro\cyp4b1.2, Xtro\cyp26c1, Xtro\LOC100488227, Xtro\cyp26b1, Xtro\cyp3a5, Xtro\cyp4v2, Xtro\cyp26a1, Xtro\LOC100487918, Xtro\cyp20a1, Xtro\cyp4f22, Xtro\tbxas1" "Mmus\Cyp4f13, Mmus\Cyp3a13, Mmus\Cyp4f39, Mmus\Cyp4f15, Mmus\Cyp4x1, Mmus\Cyp4f14, Mmus\Tbxas1, Mmus\Cyp46a1, Mmus\Cyp4a12a, Mmus\Cyp26c1, Mmus\Cyp3a44, Mmus\Cyp3a41b, Mmus\Cyp3a59, Mmus\Cyp4a31, Mmus\Cyp19a1, Mmus\Cyp4a14, Mmus\Cyp4f18, Mmus\Cyp4a10, Mmus\Cyp3a25, Mmus\Cyp4a12b, Mmus\Cyp4b1, Mmus\Cyp3a57, Mmus\Cyp4f16, Mmus\Cyp4f17, Mmus\Cyp3a41a, Mmus\Cyp4f40, Mmus\Cyp3a16, Mmus\Cyp4a32, Mmus\Cyp3a11, Mmus\Cyp26a1, Mmus\Cyp4f37, Mmus\Cyp20a1, Mmus\Cyp26b1, Mmus\Cyp4v3" "Hsap\CYP4A22, Hsap\CYP3A5, Hsap\CYP3A4, Hsap\CYP19A1, Hsap\CYP26B1, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4X1, Hsap\CYP4V2, Hsap\CYP46A1, Hsap\CYP4F11, Hsap\CYP26C1, Hsap\CYP3A43, Hsap\CYP20A1, Hsap\CYP4F12, Hsap\TBXAS1, Hsap\CYP4F22, Hsap\CYP4F3, Hsap\CYP4B1, Hsap\CYP4A11, Hsap\CYP4F2, Hsap\CYP4Z1, Hsap\CYP26A1" FBgn0262375 mir-1005 mir-1005 stem loop http://flybase.org/reports/FBgn0262375 miRNA_gene - - - "mir-1005, dme-mir-1005, CR42895, miR-1005" - CR42895 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036617 Cpr72Ea Cuticular protein 72Ea http://flybase.org/reports/FBgn0036617 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr72Ea, CG4818" IPR000618:Insect cuticle protein CG4818 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0026083 tyf twenty-four http://flybase.org/reports/FBgn0026083 FBgn0026082 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Atx2 positive regulation of translation ; GO:0045727 | inferred from direct assay locomotor rhythm ; GO:0045475 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype - "EG:EG0007.4, EG:EG0007.12, tyf, CG4857, CG485, TYF" - CG4857 11-Aug-17 DroID_v2017_08 - - - - - - "circadian behavior defective,locomotor rhythm defective,viable,fertile,recessive,circadian rhythm defective" embryonic/larval hemocyte | third instar larval stage FBgn0019772 l(1)47 lethal (1) 47 http://flybase.org/reports/FBgn0019772 - gene - - - l(1)47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085277 CG34248 - http://flybase.org/reports/FBgn0085277 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34248 - CG34248 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020314 anon-95ABa anon-95ABa http://flybase.org/reports/FBgn0020314 - gene - - - "10A2, anon-95ABa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003102 PL(2)sp-S3 Polygenic locus sternopleural S3 http://flybase.org/reports/FBgn0003102 - gene - - - "PL(2)sp[S3], II, PL(2)sp-S3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039324 CG10553 - http://flybase.org/reports/FBgn0039324 protein_coding_gene - - - "CT29612, CG10553" "IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227" CG10553 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\nhr-246, Cele\C29F7.2, Cele\dhs-27, Cele\F59B1.10, Cele\H06H21.8, Cele\C29F7.1, Cele\F59B1.8" - - - viable FBgn0022310 l(1)J67.3 lethal (1) J67.3 http://flybase.org/reports/FBgn0022310 - gene - - - "J67.3, l(1)J67.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010461 l(2)00297 lethal (2) 00297 http://flybase.org/reports/FBgn0010461 - gene - - - l(2)00297 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011144 l(1)Q220 lethal (1) Q220 http://flybase.org/reports/FBgn0011144 FBgn0010210 gene - - - l(1)Q220 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264473 CR43881 - http://flybase.org/reports/FBgn0264473 non_protein_coding_gene - - - CR43881 - CR43881 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035850 Atg18a Autophagy-related 18a http://flybase.org/reports/FBgn0035850 protein_coding_gene "phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from electronic annotation with InterPro:IPR032911 phosphatidylinositol-3,5-bisphosphate binding ; GO:0080025 | inferred from electronic annotation with InterPro:IPR032911" cellular response to starvation ; GO:0009267 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from mutant phenotype glycophagy ; GO:0061723 | inferred from mutant phenotype negative regulation of phosphatidylinositol 3-kinase signaling ; GO:0014067 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype larval midgut histolysis ; GO:0035069 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype macroautophagy ; GO:0016236 | inferred from mutant phenotype pre-autophagosomal structure ; GO:0000407 | inferred from electronic annotation with InterPro:IPR032911 "ATG18, CG7986, Atg18, atg18, Atg18a, ATG18.1, Atg18A" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032911:WD repeat domain phosphoinositide-interacting protein 2" CG7986 11-Aug-17 DroID_v2017_08 "Drer\wipi1, Drer\wdr45b, Drer\wipi2, Drer\wdr45, Drer\LOC100332293" "Scer\ATG18, Scer\ATG21, Scer\HSV2" "Cele\atg-18, Cele\epg-6" "Xtro\wipi1, Xtro\wipi2, Xtro\wdr45b" "Mmus\Wdr45, Mmus\Wipi1, Mmus\Wipi2" "Hsap\WIPI1, Hsap\WDR45, Hsap\WDR45B, Hsap\WIPI2" "lethal - all die before end of larval stage,recessive,stress response defective,neuroanatomy defective,decreased cell growth,some die during larval stage,viable,immune response defective" "embryonic/larval midgut,neuromuscular junction,NMJ bouton,embryonic/larval fat body,embryonic/larval salivary gland,somatic clone | third instar larval stage" FBgn0011915 tRNA:Met-CAT-1-1 transfer RNA:Methionine-CAT 1-1 http://flybase.org/reports/FBgn0011915 "FBgn0003807, FBgn0050255, FBgn0060137" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "CR30255, AE002787.trna34-MetCAT, tRNA:M:CAT:AE002787-d, tRNA:met2:48Ba, chr2R.trna16-MetCAT, tRNA-Met[CAU], tRNA-Met-CAT-1-1, tRNA:Met-CAT-1-1, tRNA:M2:48Ba" - CR30255 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069109 mus315 mutagen-sensitive 315 http://flybase.org/reports/FBgn0069109 gene - - - mus315 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0260775 DnaJ-60 DnaJ-like-60 http://flybase.org/reports/FBgn0260775 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with ECOGENE:EG10240 protein folding ; GO:0006457 | inferred from sequence or structural similarity with ECOGENE:EG10240 spermatogenesis ; GO:0007283 | inferred from expression pattern membrane ; GO:0016020 | inferred from sequence model "CG42567, DnaJ-60, anon-WO0172774.147, CG12240, DmJ60, DnaJ60" IPR001623:DnaJ domain CG42567 11-Aug-17 DroID_v2017_08 "Drer\dnajc16l, Drer\dnajc4, Drer\dnaja3b, Drer\dnajc24, Drer\dnajc16, Drer\dnaja3a" Scer\MDJ1 "Cele\dnj-4, Cele\dnj-3" "Xtro\dnajc16, Xtro\dnajc4, Xtro\dnajc24" "Mmus\Dnajc24, Mmus\Dnajc16, Mmus\Dnajc4, Mmus\Dnaja3" "Hsap\DNAJA3, Hsap\DNAJC24, Hsap\DNAJC16, Hsap\DNAJC4" FBgn0053415 5SrRNA:CR33415 5SrRNA:CR33415 http://flybase.org/reports/FBgn0053415 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33415, 5SrRNA:CR33415" - CR33415 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001687 l(1)ESHS8 lethal (1) ESHS8 http://flybase.org/reports/FBgn0001687 - gene - - - l(1)ESHS8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052596 CG32596 - http://flybase.org/reports/FBgn0052596 protein_coding_gene - - - CG32596 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035986 CG4022 - http://flybase.org/reports/FBgn0035986 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG4022 "IPR012981:PIH1 domain, IPR011989:Armadillo-like helical" CG4022 11-Aug-17 DroID_v2017_08 Drer\pih1d2 - Cele\F32D8.4 Xtro\pih1d2 Mmus\Pih1d2 Hsap\PIH1D2 "viable,fertile,visible" trichogen cell FBgn0064166 l(3)AP1 lethal (3) AP1 http://flybase.org/reports/FBgn0064166 gene - - - l(3)AP1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010331 Sebp344 Secretion enhancer-binding protein 344 http://flybase.org/reports/FBgn0010331 - gene - - - Sebp344 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265932 CR44721 - http://flybase.org/reports/FBgn0265932 non_protein_coding_gene - - - "CR44721, lincRNA.508" - CR44721 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053251 CG33251 - http://flybase.org/reports/FBgn0053251 protein_coding_gene - - - CG33251 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000449 dib disembodied http://flybase.org/reports/FBgn0000449 FBgn0035492 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 ecdysteroid 22-hydroxylase activity ; GO:0042767 | inferred from direct assay electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 midgut development ; GO:0007494 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from direct assay dorsal closure ; GO:0007391 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity mitochondrion ; GO:0005739 | inferred from direct assay "Cyp302a1, CYP302A1, 302a1, CG12028, l(3)dib, l(3)SH14, l(3)64Ak, dib, Dib, Cyp" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG12028 11-Aug-17 DroID_v2017_08 "Drer\cyp27b1, Drer\si:dkey-91i10.3, Drer\cyp27c1, Drer\si:ch211-113j14.1, Drer\cyp27a1.4, Drer\zgc:136333, Drer\cyp27a7, Drer\cyp24a1, Drer\cyp11a2, Drer\cyp11c1, Drer\cyp27a1.2" Scer\DIT2 "Cele\cyp-35B3, Cele\cyp-35A5, Cele\cyp-33D1, Cele\cyp-35A3, Cele\cyp-35C1, Cele\cyp-44A1" "Xtro\cyp27b1, Xtro\cyp27a1, Xtro\cyp27c1, Xtro\LOC100145331, Xtro\cyp11a1, Xtro\cyp24a1" "Mmus\Cyp27b1, Mmus\Cyp11b2, Mmus\Cyp11b1, Mmus\Cyp11a1, Mmus\Cyp24a1, Mmus\Cyp27a1" "Hsap\CYP11B1, Hsap\CYP11B2, Hsap\CYP11A1, Hsap\CYP27B1, Hsap\CYP27A1, Hsap\CYP27C1, Hsap\CYP24A1" " embryonic stage | early , oogenesis stage | stage S8-11 && adult stage | female , embryonic stage | extended germ band , larval stage | third instar , embryonic stage | stage 14-17 " "

anterior , follicle cell

, embryonic epidermis

, ring gland && prothoracic segment

, ring gland && embryonic prothoracic segment

, organism | striped & posterior

" "viable,fertile,wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,memory defective,RU486 conditional,large body,developmental rate defective" "presumptive embryonic/larval central nervous system,dorsal closure embryo,stage 14 embryo,midgut primordium,hindgut proper primordium,midgut constriction,yolk granule,embryonic/first instar larval cuticle,denticle belt,dorsal hair,cephalopharyngeal skeleton,embryonic ventral epidermis,ventral nerve cord,embryonic/larval midgut,embryonic/larval foregut,embryonic/larval hindgut,commissure,longitudinal connective,glial cell,midline glial cell,ectopic,embryonic head,pupa,mouth hooks" FBgn0000844 fs(1)M31 female sterile (1) M31 http://flybase.org/reports/FBgn0000844 - gene - - - fs(1)M31 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0025720 Ate1 Ate1 http://flybase.org/reports/FBgn0025720 FBgn0021941 protein_coding_gene arginyltransferase activity ; GO:0004057 | inferred from biological aspect of ancestor with PANTHER:PTN000482991 protein arginylation ; GO:0016598 | inferred from biological aspect of ancestor with PANTHER:PTN000482991 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000482991 "Ate, CG9204, ATE1, ate1, Dm-Ate1, l(2)k10809, Ate1" "IPR007471:Arginine-tRNA-protein transferase, N-terminal, IPR007472:Arginine-tRNA-protein transferase, C-terminal, IPR017137:Arginine-tRNA-protein transferase 1, eukaryotic, IPR030700:Arginine-tRNA-protein transferase, IPR016181:Acyl-CoA N-acyltransferase" CG9204 11-Aug-17 DroID_v2017_08 Drer\ate1 Scer\ATE1 Cele\K07A1.9 Xtro\ate1 Mmus\Ate1 Hsap\ATE1 "lethal,recessive,viable" FBgn0033544 CG7220 - http://flybase.org/reports/FBgn0033544 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1914049 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000630458 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630458 protein monoubiquitination ; GO:0006513 | inferred from sequence or structural similarity with MGI:MGI:1914049 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000630458 "BEST:GH28095, BcDNA:GH28095, CG7220, Ube2W" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG7220 11-Aug-17 DroID_v2017_08 "Drer\ube2w, Drer\impad1, Drer\flj11011l" Scer\UBC4 "Cele\ubc-16, Cele\gpap-1" "Xtro\ube2w, Xtro\impad1" "Mmus\Impad1, Mmus\Ube2w" "Hsap\IMPAD1, Hsap\UBE2W" "lethal,viable" FBgn0033972 Ciao1 Ciao1 http://flybase.org/reports/FBgn0033972 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with UniProtKB:O76071 iron-sulfur cluster assembly ; GO:0016226 | inferred from biological aspect of ancestor with PANTHER:PTN000460364 CIA complex ; GO:0097361 | inferred from biological aspect of ancestor with PANTHER:PTN000460364 "CG12797, Ciao1, CiaO1" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR028608:Probable cytosolic iron-sulfur protein assembly protein, CIAO1/Cia1" CG12797 11-Aug-17 DroID_v2017_08 "Drer\nif3l1, Drer\ciao1" Scer\CIA1 Cele\Y18D10A.9 "Xtro\nif3l1, Xtro\ciao1" "Mmus\Ciao1, Mmus\Nif3l1" Hsap\CIAO1 "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0261552 ps pasilla http://flybase.org/reports/FBgn0261552 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with HGNC:7886 inferred from sequence or structural similarity with HGNC:7887 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from expression pattern" nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "ps, PS, NOVA1, CG42670, CG16765, cg8144, EP(3)3406, l(3)10615, CG16776, BcDNA:RE47781, CG18509, CG8144, CG16777" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG42670 11-Aug-17 DroID_v2017_08 "Drer\nova2, Drer\nova1" Scer\PBP2 Cele\Y59A8B.10 "Xtro\nova2, Xtro\nova1" "Mmus\Nova2, Mmus\Nova1" "Hsap\NOVA1, Hsap\NOVA2" """DRSC16388, DRSC22989"" " IEK FBgn0264448 CR43866 - http://flybase.org/reports/FBgn0264448 non_protein_coding_gene - - - CR43866 - CR43866 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039336 CG4553 - http://flybase.org/reports/FBgn0039336 protein_coding_gene - - - CG4553 IPR010487:Neugrin/Rrg9 CG4553 11-Aug-17 DroID_v2017_08 Drer\ngrn - - - Mmus\Ngrn Hsap\NGRN viable FBgn0082358 HM17 HM17 http://flybase.org/reports/FBgn0082358 gene - - - HM17 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267225 CR45665 - http://flybase.org/reports/FBgn0267225 non_protein_coding_gene - - - CR45665 - CR45665 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082910 60-15 60-15 http://flybase.org/reports/FBgn0082910 gene - - - 60-15 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023128 anon-10Aaa anon-10Aaa http://flybase.org/reports/FBgn0023128 - gene - - - "20, anon-10Aaa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029825 CG12728 - http://flybase.org/reports/FBgn0029825 protein_coding_gene - double-strand break repair ; GO:0006302 | inferred from electronic annotation with InterPro:IPR015381 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR015381 "CG12728, XRCC4" IPR015381:XLF family CG12728 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027644 l(3)CL-R lethal (3) Cell Lethal Right http://flybase.org/reports/FBgn0027644 - gene - - - "CL3R, l(3)CL-R" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262836 CG43200 - http://flybase.org/reports/FBgn0262836 protein_coding_gene - - - "CG43200, nc_5744.a" - CG43200 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053358 5SrRNA:CR33358 5SrRNA:CR33358 http://flybase.org/reports/FBgn0053358 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33358, 5SrRNA:CR33358" - CR33358 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000008 a arc http://flybase.org/reports/FBgn0000008 "FBgn0034701, FBgn0034702" protein_coding_gene molecular_function ; GO:0003674 | no biological data available bicellular tight junction assembly ; GO:0070830 | inferred from electronic annotation with InterPro:IPR029906 compound eye development ; GO:0048749 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay "a, CG13505, Arc, CG6741, bran" "IPR001478:PDZ domain, IPR029906:FERM and PDZ domain-containing protein 2, IPR015943:WD40/YVTN repeat-like-containing domain" CG6741 11-Aug-17 DroID_v2017_08 "Drer\frmpd2, Drer\cox16, Drer\pdzd2, Drer\synj2bp, Drer\il16" - "Cele\mics-1, Cele\pqn-92, Cele\Y75B8A.28, Cele\Y75B8A.39" - "Mmus\Synj2bp, Mmus\Pdzd2, Mmus\Il16, Mmus\Cox16, Mmus\Synj2bp-cox16" "Hsap\PDZD2, Hsap\SYNJ2BP, Hsap\IL16, Hsap\SYNJ2BP-COX16, Hsap\FRMPD2, Hsap\COX16" " embryonic stage , embryonic stage | stage >=6 , larval stage | third instar , embryonic stage | early , embryonic stage | stage >12 , embryonic stage | stage >=10 " " embryonic/larval salivary gland

, posterior midgut proper primordium

, embryonic/larval foregut

, morphogenetic furrow

,

anterior posterior gradient , embryonic/larval hindgut

, Malpighian tubule

" " embryonic stage , embryonic stage | stage >=6 , embryonic stage | stage >13 , embryonic stage | stage >=10 , larval stage | third instar " " embryonic/larval salivary gland

, posterior midgut proper primordium

, embryonic/larval foregut

, embryonic/larval hindgut

, Malpighian tubule

, morphogenetic furrow

" "lethal,visible,dominant,viable,recessive,wild-type,sterile,lethal - all die before end of pupal stage,some die during pupal stage" "wing,eye,ommatidium,posterior scutellar bristle,macrochaeta,crossvein" FBgn0025498 l(3)73Bf lethal (3) 73Bf http://flybase.org/reports/FBgn0025498 - gene - - - l(3)73Bf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065665 l(2)SH0701 lethal (2) SH0701 http://flybase.org/reports/FBgn0065665 gene - - - "l(2)SH0701, l(2)SH2 0701" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265375 CR44316 - http://flybase.org/reports/FBgn0265375 non_protein_coding_gene - - - "CR44316, lincRNA.291" - CR44316 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034828 CG13545 - http://flybase.org/reports/FBgn0034828 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13545 - CG13545 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0002096 l(2)57Cb lethal (2) 57Cb http://flybase.org/reports/FBgn0002096 - gene - - - l(2)57Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016885 l(2)39DEj lethal (2) 39DEj http://flybase.org/reports/FBgn0016885 - gene - - - "D244, l(2)39DEj" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001897 l(2)21Fc lethal (2) 21Fc http://flybase.org/reports/FBgn0001897 - gene - - - "l(2)neh-11, l(2)neh11, l(2)21Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265068 CR44179 - http://flybase.org/reports/FBgn0265068 non_protein_coding_gene - - - CR44179 - CR44179 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052075 CG32075 - http://flybase.org/reports/FBgn0052075 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG6316, CG32075" IPR007174:Las1-like CG32075 11-Aug-17 DroID_v2017_08 Drer\las1l Scer\LAS1 Cele\Y6B3B.9 - Mmus\Las1l Hsap\LAS1L "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0041635 EM3-1 EM3-1 http://flybase.org/reports/FBgn0041635 gene - - - EM3-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040031 CG12061 - http://flybase.org/reports/FBgn0040031 protein_coding_gene "calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 potassium ion binding ; GO:0030955 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium, potassium:sodium antiporter activity ; GO:0008273 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 sodium ion binding ; GO:0031402 | inferred from biological aspect of ancestor with PANTHER:PTN000090975" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 cellular calcium ion homeostasis ; GO:0006874 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 "CG40148, CG12061" "IPR004837:Sodium/calcium exchanger membrane region, IPR004481:Sodium/potassium/calcium exchanger" CG12061 11-Aug-17 DroID_v2017_08 "Drer\slc24a1, Drer\slc24a2, Drer\slc24a3, Drer\si:ch73-335m24.5, Drer\slc24a5, Drer\slc24a4a, Drer\slc24a4b" Scer\YDL206W "Cele\ncx-5, Cele\ncx-4" "Xtro\slc24a3, Xtro\slc24a4, Xtro\slc24a5, Xtro\slc24a2" "Mmus\Slc24a5, Mmus\Slc24a1, Mmus\Slc24a4, Mmus\Slc24a3, Mmus\Slc24a2" "Hsap\SLC24A5, Hsap\SLC24A2, Hsap\SLC24A3, Hsap\SLC24A1, Hsap\SLC24A4" viable FBgn0261627 CG42710 - http://flybase.org/reports/FBgn0261627 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42710, HDC01517" - CG42710 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060681 l(3)S076304 lethal (3) S076304 http://flybase.org/reports/FBgn0060681 gene - - - "0763/04, l(3)S076304" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0014856 Gyc89A Guanylyl cyclase at 89A http://flybase.net/reports/FBgn0014856.html gene "0004383=guanylate cyclase activity, 0004872=receptor activity" 0007165=signal transduction 0005886=plasma membrane DrGC-2 11-Aug-17 DroID_v2017_08 FBgn0031951 r2d2 r2d2 http://flybase.org/reports/FBgn0031951 protein_coding_gene double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity regulation of production of small RNA involved in gene silencing by RNA ; GO:0070920 | inferred from direct assay heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype siRNA loading onto RISC involved in RNA interference ; GO:0035087 | inferred from direct assay ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from direct assay siRNA loading onto RISC involved in RNA interference ; GO:0035087 | traceable author statement production of small RNA involved in gene silencing by RNA ; GO:0070918 | inferred from direct assay RISC complex ; GO:0016442 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "r2d2, R2D2, cg7138, CG7138, R2d2" IPR014720:Double-stranded RNA-binding domain CG7138 11-Aug-17 DroID_v2017_08 "Drer\ilf3a, Drer\adarb1a, Drer\prkra, Drer\ilf3b, Drer\strbp, Drer\adarb1b, Drer\stau2, Drer\tarbp2, Drer\stau1, Drer\adarb2" - "Cele\stau-1, Cele\R11H6.5" "Xtro\tarbp2, Xtro\stau1, Xtro\stau2" "Mmus\Stau1, Mmus\Stau2, Mmus\Adarb1, Mmus\Prkra, Mmus\Strbp, Mmus\Tarbp2, Mmus\Adarb2, Mmus\Ilf3" "Hsap\STAU1, Hsap\STAU2, Hsap\STRBP, Hsap\ILF3, Hsap\TARBP2, Hsap\ADARB1, Hsap\PRKRA, Hsap\ADARB2" "immune response defective,recessive,lethal,maternal effect,suppressor of variegation,dominant,conditional,visible,partially lethal - majority die,some die during pupal stage" "interfollicle cell,follicle cell,egg chamber,somatic clone,trichogen cell" FBgn0045045 fs(1)38 female sterile (1) 38 http://flybase.org/reports/FBgn0045045 gene molecular_function ; GO:0003674 | no biological data available eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)38 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg,chorion" FBgn0259538 GG01022 - http://flybase.org/reports/FBgn0259538 gene - - - GG01022 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,unguis,tarsal segment,arista" FBgn0065955 l(2)SH0062 lethal (2) SH0062 http://flybase.org/reports/FBgn0065955 gene - - - "l(2)SH0062, l(2)SH2 0062" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037517 CG10086 - http://flybase.org/reports/FBgn0037517 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10086 "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG10086 11-Aug-17 DroID_v2017_08 "Drer\zgc:110353, Drer\zgc:110626, Drer\arrdc3a, Drer\arrdc1a, Drer\txnipb, Drer\si:ch211-130m23.2, Drer\arrdc1b, Drer\arrdc3b, Drer\LOC799768, Drer\arrdc2, Drer\txnipa" "Scer\ROG3, Scer\LDB19, Scer\RIM8, Scer\ALY2, Scer\ALY1, Scer\ECM21, Scer\ROD1, Scer\ART5, Scer\CSR2" "Cele\arrd-13, Cele\arrd-3, Cele\arrd-9, Cele\arrd-4, Cele\arrd-14, Cele\arrd-1, Cele\arrd-6, Cele\arrd-5, Cele\arrd-15, Cele\arrd-18, Cele\arrd-2, Cele\arrd-11, Cele\arrd-25, Cele\arrd-23, Cele\arrd-8, Cele\rnh-1.2, Cele\arrd-16, Cele\arrd-19, Cele\arrd-27, Cele\arrd-24, Cele\arrd-7, Cele\arrd-22, Cele\arrd-12" "Xtro\arrdc4, Xtro\txnip, Xtro\arrdc3, Xtro\arrdc2" "Mmus\Txnip, Mmus\Arrdc1, Mmus\Arrdc4, Mmus\Arrdc5, Mmus\Arrdc2, Mmus\Arrdc3" "Hsap\ARRDC2, Hsap\ARRDC4, Hsap\ARRDC1, Hsap\TXNIP, Hsap\ARRDC5, Hsap\ARRDC3" viable FBgn0260077 2L0944 - http://flybase.org/reports/FBgn0260077 gene - - - 2L0944 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0021960 l(2)k10127 lethal (2) k10127 http://flybase.net/reports/FBgn0021960.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0058441 CR40441 - http://flybase.org/reports/FBgn0058441 pseudogene_attribute - - - "CR40441, CG40441" - CR40441 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261538 CG42662 - http://flybase.org/reports/FBgn0261538 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42662 - CG42662 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001260 inaA inactivation no afterpotential A http://flybase.org/reports/FBgn0001260 - gene - - - inaA - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,visual behavior defective" "photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6" FBgn0265547 CR44397 - http://flybase.org/reports/FBgn0265547 non_protein_coding_gene - - - "CR44397, lincRNA.176" - CR44397 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037751 topi matotopetli http://flybase.org/reports/FBgn0037751 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein binding ; GO:0005515 | inferred from physical interaction with wuc protein binding ; GO:0005515 | inferred from physical interaction with comr positive regulation of transcription involved in meiotic cell cycle ; GO:0051039 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype nuclear chromatin ; GO:0000790 | inferred from direct assay "CG8484, topi, Topi" IPR013087:Zinc finger C2H2-type CG8484 11-Aug-17 DroID_v2017_08 "Drer\LOC100330167, Drer\si:dkey-208k4.2, Drer\si:dkey-56e3.3" Scer\PZF1 "Cele\Y55F3AM.14, Cele\mep-1, Cele\Y111B2A.10, Cele\pzf-1, Cele\spr-4, Cele\hinf-1" - Mmus\Zfp688 "Hsap\ZNF543, Hsap\ZBTB24, Hsap\ZNF331, Hsap\ZNF785" "meiotic cell cycle defective,male,male sterile,viable,female fertile" "spermatid,secondary spermatocyte,nuclear chromosome & primary spermatocyte,primary spermatocyte & nuclear chromosome,primary spermatocyte & nuclear chromosomeby10)" FBgn0022312 l(1)H30.1 lethal (1) H30.1 http://flybase.org/reports/FBgn0022312 - gene - - - "H30.1, l(1)H30.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029897 RpL17 Ribosomal protein L17 http://flybase.org/reports/FBgn0029897 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001063, InterPro:IPR005721, InterPro:IPR018260 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001063, InterPro:IPR005721, InterPro:IPR018260 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement" large ribosomal subunit ; GO:0015934 | inferred from electronic annotation with InterPro:IPR005721 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG3203, anon-EST:Posey276, RpL17, Rpl17" "IPR018260:Ribosomal protein L22/L17, conserved site, IPR001063:Ribosomal protein L22/L17, IPR005721:Ribosomal protein L22/L17, eukaryotic/archaeal" CG3203 11-Aug-17 DroID_v2017_08 Drer\rpl17 "Scer\RPL17A, Scer\RPL17B" "Cele\rpl-17, Cele\sir-2.4" "Xtro\rpl17, Xtro\sirt6" "Mmus\Sirt6, Mmus\Rpl17" "Hsap\SIRT6, Hsap\RPL17-C18orf32, Hsap\C18orf32, Hsap\RPL17" "viable,fertile,lethal" DRSC18293 IEK -1.788815557 -1.577283294 -0.596978383 -4.520636137 1.872277332 2.38221562 FBgn0028119 l(3)S061207 lethal (3) S061207 http://flybase.org/reports/FBgn0028119 gene - - - "1226/12, 0671/10, 0612/07, l(3)S122612a, l(3)S061207" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0085788 CR41504 - http://flybase.org/reports/FBgn0085788 pseudogene_attribute - - - CR41504 - CR41504 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005390 fs(1)M3 female sterile (1) M3 http://flybase.org/reports/FBgn0005390 "FBgn0000816, FBgn0004681, FBgn0029829" protein_coding_gene - chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence or structural similarity external side of plasma membrane ; GO:0009897 | inferred from direct assay "fs(1)ph, fs(1)polehole, fs(1)phl, fs(1)pole hole, fs(1)K646, Fs(1)K646, CG4790, fs(1)M3" IPR015943:WD40/YVTN repeat-like-containing domain CG4790 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,maternal effect,viable" "vitelline membrane,egg,cephalopharyngeal skeleton,maternal effect,head,anterior,telson,abdominal segment 8,ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 9,abdominal segment 10,labrum,ocular segment,cephalic furrow,terminalia,embryo,posterior,embryonic abdominal segment 8" FBgn0052277 CG32277 - http://flybase.org/reports/FBgn0052277 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP183, CG11531, CG32277" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG32277 11-Aug-17 DroID_v2017_08 - - "Cele\try-1, Cele\svh-1" - Mmus\Klk10 "Hsap\CELA2A, Hsap\KLK10" FBgn0085400 CG34371 - http://flybase.org/reports/FBgn0085400 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG34371, CG13548, CT32921, CT32922, CG13547, CG13546, CG30188, 34371" "IPR013162:CD80-like, immunoglobulin C2-set, IPR007110:Immunoglobulin-like domain, IPR003961:Fibronectin type III, IPR003599:Immunoglobulin subtype, IPR003598:Immunoglobulin subtype 2, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain" CG34371 11-Aug-17 DroID_v2017_08 Drer\nphs1 - - Xtro\nphs1 Mmus\Nphs1 "Hsap\NPHS1, Hsap\MERTK, Hsap\PSG1" viable FBgn0027132 l(3)B5-1 lethal (3) B5-1 http://flybase.org/reports/FBgn0027132 - gene - - - l(3)B5-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265980 CR44759 - http://flybase.org/reports/FBgn0265980 non_protein_coding_gene - - - "lincRNA.374, CR44759" - CR44759 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060937 l(3)S040708b lethal (3) S040708b http://flybase.org/reports/FBgn0060937 gene - - - "0407/08, l(3)S040708b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041144 l(1)1Bm lethal (1) 1Bm http://flybase.org/reports/FBgn0041144 gene - - - l(1)1Bm - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030657 cerv cervantes http://flybase.org/reports/FBgn0030657 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181 SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000000745 double-strand break repair via homologous recombination ; GO:0000724 | inferred from electronic annotation with InterPro:IPR026846 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000000745 Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000000745 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000745 "cerv, CG15645, Cerv" "IPR004181:Zinc finger, MIZ-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR026846:E3 SUMO-protein ligase Nse2 (Mms21)" CG15645 11-Aug-17 DroID_v2017_08 Drer\nsmce2 Scer\MMS21 Cele\ZK1248.11 - Mmus\Nsmce2 Hsap\NSMCE2 viable FBgn0036576 CG5151 - http://flybase.org/reports/FBgn0036576 protein_coding_gene - - - CG5151 - CG5151 11-Aug-17 DroID_v2017_08 Drer\ldlrad4b - - - Mmus\Ldlrad4 Hsap\LDLRAD4 "viable,fertile" FBgn0016855 l(1)N36 lethal (1) N36 http://flybase.org/reports/FBgn0016855 - gene - - - "l(1)N36, N36" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027505 Rab3-GAP Rab3 GTPase activating protein http://flybase.org/reports/FBgn0027505 - protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with UniProtKB:Q5U1Z0 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000279859 enzyme regulator activity ; GO:0030234 | inferred from sequence or structural similarity with UniProtKB:Q5U1Z0 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000279859 regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from biological aspect of ancestor with PANTHER:PTN000279859 neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with UniProtKB:Q5U1Z0 synaptic vesicle ; GO:0008021 | non-traceable author statement "BcDNA:LD23336, CG7061, rab3-GAP, Rab3-GAP" "IPR032839:Rab3-GAP regulatory subunit, N-terminal, IPR029257:Rab3GAP regulatory subunit, C-terminal, IPR026059:Rab3-GAP regulatory subunit" CG7061 11-Aug-17 DroID_v2017_08 Drer\rab3gap2 - Cele\rbg-2 Xtro\rab3gap2 Mmus\Rab3gap2 Hsap\RAB3GAP2 "neurophysiology defective,chemical sensitive,cell migration defective,viable" border follicle cell FBgn0037981 Spt3 Spt3 http://flybase.org/reports/FBgn0037981 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11466 inferred from sequence or structural similarity with SGD:S000002800 SAGA complex ; GO:0000124 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from sequence or structural similarity with HGNC:11466 inferred from sequence or structural similarity with SGD:S000002800 nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11466 inferred from sequence or structural similarity with SGD:S000002800 "dSpt3, TFIID, SPT3, CG3169, Spt3" "IPR003195:Transcription initiation factor IID, subunit 13, IPR009072:Histone-fold" CG3169 11-Aug-17 DroID_v2017_08 Drer\supt3h "Scer\TAF13, Scer\SPT3" Cele\taf-13 "Xtro\supt3h, Xtro\taf13" "Mmus\Taf13, Mmus\Supt3" "Hsap\TAF13, Hsap\SUPT3H" viable FBgn0005742 l(1)TK234 lethal (1) TK234 http://flybase.org/reports/FBgn0005742 - gene - - - "l234, l(1)TK234" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye FBgn0267533 CR45873 - http://flybase.org/reports/FBgn0267533 non_protein_coding_gene - - - CR45873 - CR45873 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033069 eIF3f2 eukaryotic translation initiation factor 3 subunit f2 http://flybase.org/reports/FBgn0033069 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000056988 translation initiation factor binding ; GO:0031369 | inferred from biological aspect of ancestor with PANTHER:PTN000056988 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:3275 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:3275 translational initiation ; GO:0006413 | inferred from sequence or structural similarity translational initiation ; GO:0006413 | inferred from biological aspect of ancestor with PANTHER:PTN000056988 "eukaryotic translation initiation factor 3 complex, eIF3m ; GO:0071541 | inferred from biological aspect of ancestor with PANTHER:PTN000056988 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity" "eIF3-S5, CG8335, eIF3f, eIF3f2" "IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR024969:Rpn11/EIF3F, C-terminal, IPR027531:Eukaryotic translation initiation factor 3 subunit F" CG8335 11-Aug-17 DroID_v2017_08 Drer\eif3f Scer\RPN8 Cele\eif-3.F Xtro\eif3f Mmus\Eif3f Hsap\EIF3F viable FBgn0040124 l(2)23CDd lethal (2) 23CDd http://flybase.org/reports/FBgn0040124 gene - - - l(2)23CDd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000883 fs(1)M81 female sterile (1) M81 http://flybase.org/reports/FBgn0000883 - gene - - - fs(1)M81 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0264262 CR43762 - http://flybase.org/reports/FBgn0264262 non_protein_coding_gene - - - CR43762 - CR43762 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033682 CG18344 - http://flybase.org/reports/FBgn0033682 protein_coding_gene - - - CG18344 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025631 moody moody http://flybase.org/reports/FBgn0025631 FBgn0041254 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype behavioral response to nicotine ; GO:0035095 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype behavioral response to cocaine ; GO:0048148 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay pleated septate junction ; GO:0005919 | inferred from direct assay" "CG4322, 1631, EG:22E5.11, EP1631, moody, Moody" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG4322 11-Aug-17 DroID_v2017_08 "Drer\npy8br, Drer\npy2rl, Drer\prlhr2b, Drer\npy1r, Drer\gpr19, Drer\tmtops2a, Drer\mchr1a, Drer\npy2r, Drer\npy8ar, Drer\mtnr1ba, Drer\mtnr1ab, Drer\gpr88, Drer\prokr1a, Drer\mchr1b, Drer\tmtops2b, Drer\mtnr1c, Drer\prlhr2a, Drer\gpr84, Drer\npy4r, Drer\mtnr1bb, Drer\mtnr1aa, Drer\prokr1b" - "Cele\npr-10, Cele\npr-17, Cele\npr-6" "Xtro\LOC100490436, Xtro\gpr84" "Mmus\Mchr1, Mmus\Npy1r, Mmus\Gpr84, Mmus\Npy6r, Mmus\Npy5r, Mmus\Npy2r, Mmus\Mtnr1b, Mmus\Mtnr1a, Mmus\Npy4r, Mmus\Prokr2, Mmus\Gpr19, Mmus\Prokr1, Mmus\Gpr88, Mmus\Prlhr" "Hsap\MCHR1, Hsap\MTNR1A, Hsap\NPY5R, Hsap\PROKR1, Hsap\PRLHR, Hsap\NPY2R, Hsap\NPY1R, Hsap\GPR88, Hsap\MTNR1B, Hsap\NPY4R, Hsap\GPR84, Hsap\GPR19, Hsap\GPR50, Hsap\PROKR2" "lethal,neuroanatomy defective,behavior defective,viable,chemosensitive behavior defective,partially lethal - majority die,male,recessive,some die during larval stage" "germline cell,ectopic,maternal effect,germline cell | embryonic stage" FBgn0043534 Obp57b Odorant-binding protein 57b http://flybase.org/reports/FBgn0043534 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 transport ; GO:0006810 | non-traceable author statement sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "57b, Obp-e, anon-AE003792.2, CG30142, Obp57b, DmelObp57b, obp57b" IPR006170:Pheromone/general odorant binding protein CG30142 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21914 E -0.231921409 -0.137454033 1.047696293 1.768157677 -0.578103034 0.684722944 FBgn0039966 Rab21 Rab21 http://flybase.org/reports/FBgn0039966 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 phosphatidylinositol 3-kinase catalytic subunit binding ; GO:0036313 | inferred from physical interaction with Pi3K68D protein binding ; GO:0005515 | inferred from physical interaction with Sbf" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 positive regulation of autophagosome maturation ; GO:1901098 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from biological aspect of ancestor with PANTHER:PTN000634504 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 SNARE complex ; GO:0031201 | colocalizes_with inferred from physical interaction with Vamp7 synapse ; GO:0045202 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 recycling endosome ; GO:0055037 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay "CG17515, AAF45341, DmRab21, CG40304, anon-EST:Posey237, Rab21, rab21, Q7PLE8" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17515 11-Aug-17 DroID_v2017_08 "Drer\zgc:154045, Drer\rab22a, Drer\rab31, Drer\rab5c, Drer\rab5ab" "Scer\YPT10, Scer\VPS21, Scer\YPT52, Scer\YPT53" "Cele\rab-21, Cele\rab-5, Cele\C52B11.5, Cele\C56E6.2" "Xtro\rab5a, Xtro\rab5b, Xtro\rab22a, Xtro\rab21, Xtro\mras, Xtro\rab5c" "Mmus\Rab21, Mmus\Rab22a, Mmus\Rab31, Mmus\Rab5a, Mmus\Rab5b, Mmus\Rab5c" "Hsap\RAB5C, Hsap\RAB5A, Hsap\RAB5B, Hsap\RAB21, Hsap\RAB31, Hsap\RAB22A" macrophage DRSC20968 E 0.320072109 -0.03818283 2.295535153 0.356380935 -0.055804499 0.134998578 FBgn0259571 GG01341 - http://flybase.org/reports/FBgn0259571 gene - - - GG01341 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,unguis,antennal segment,arista,wing margin,macrochaeta,mesothoracic tergum,scutellum" FBgn0003673 tc tiny chaetae http://flybase.org/reports/FBgn0003673 - gene - - - tc - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile,lethal" macrochaeta FBgn0025629 CG4045 - http://flybase.org/reports/FBgn0025629 - protein_coding_gene tRNA (guanine-N7-)-methyltransferase activity ; GO:0008176 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q9UBP6 tRNA (guanine-N7-)-methyltransferase activity ; GO:0008176 | inferred from sequence or structural similarity with HGNC:7030 tRNA (guanine-N7-)-methyltransferase activity ; GO:0008176 | inferred from biological aspect of ancestor with PANTHER:PTN000602515 RNA (guanine-N7)-methylation ; GO:0036265 | inferred from biological aspect of ancestor with PANTHER:PTN000602515 RNA (guanine-N7)-methylation ; GO:0036265 | inferred from sequence or structural similarity with HGNC:7030 tRNA modification ; GO:0006400 | inferred from sequence or structural similarity with UniProtKB:Q9UBP6 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:7030 tRNA methyltransferase complex ; GO:0043527 | inferred from biological aspect of ancestor with PANTHER:PTN000602515 "EG:22E5.4, CG4045" "IPR003358:tRNA (guanine-N-7) methyltransferase, Trmb type, IPR025763:tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG4045 11-Aug-17 DroID_v2017_08 Drer\mettl1 Scer\TRM8 Cele\W02B12.10 Xtro\mettl1 Mmus\Mettl1 Hsap\METTL1 viable FBgn0050357 CG30357 - http://flybase.org/reports/FBgn0050357 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT27059, CG30357" "IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR031750:Domain of unknown function DUF4734" CG30357 11-Aug-17 DroID_v2017_08 Drer\klhl41a - - - - Hsap\KLHL31 viable DRSC22472 K 0.291349218 0.429186405 0.804679199 0.544522233 0.918840742 1.545064759 FBgn0028171 l(3)S027344 lethal (3) S027344 http://flybase.org/reports/FBgn0028171 gene - - - "0273/44, l(3)S027344" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0261238 Alh Alhambra http://flybase.org/reports/FBgn0261238 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:16063 inferred from sequence or structural similarity with HGNC:7138 inferred from mutant phenotype" "instar larval development ; GO:0002168 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype haltere development ; GO:0007482 | inferred from genetic interaction with Ubx regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:16063 inferred from sequence or structural similarity with HGNC:7138 inferred from direct assay "Alh, stk, Dalf, AF10, l(3)j8C8, l(3)j13A6, CG1070, anon-WO0118547.226, l(3j8C8, dAF10, l(3)j8c8, l(3)r13, l(3)g5, l(3)g2, l(3)84Be" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR034732:Extended PHD (ePHD) domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1070 11-Aug-17 DroID_v2017_08 "Drer\brd1a, Drer\jade3, Drer\brpf3b, Drer\mllt10, Drer\brpf3a, Drer\jade1" "Scer\NTO1, Scer\SNT2, Scer\HKR1" "Cele\zfp-1, Cele\phf-15, Cele\lin-49, Cele\phf-14" "Xtro\brpf3, Xtro\mllt6, Xtro\brd1, Xtro\mllt10, Xtro\jade3, Xtro\jade1" "Mmus\Brpf3, Mmus\Brd1, Mmus\Mllt10, Mmus\Brpf1, Mmus\Mllt6, Mmus\Jade1, Mmus\Jade3" "Hsap\MLLT6, Hsap\JADE3, Hsap\MLLT10, Hsap\BRPF1, Hsap\JADE1, Hsap\BRD1, Hsap\BRPF3" FBgn0045061 fs(1)127 female sterile (1) 127 http://flybase.org/reports/FBgn0045061 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)127 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "oocyte,nurse cell & nucleus" FBgn0054015 CG34015 - http://flybase.org/reports/FBgn0054015 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011146 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1006, CG34015" IPR011146:HIT-like domain CG34015 11-Aug-17 DroID_v2017_08 "Drer\hint3, Drer\si:dkey-25e12.3" Scer\HNT1 Cele\hint-3 Xtro\hint3 Mmus\Hint3 Hsap\HINT3 FBgn0082168 p160S p160S http://flybase.org/reports/FBgn0082168 gene - - - "p160, p160S" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025146 ms(3)A1 ms(3)A1 http://flybase.org/reports/FBgn0025146 - gene - - - ms(3)A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0031603 CG15432 - http://flybase.org/reports/FBgn0031603 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:24563 biological_process ; GO:0008150 | no biological data available nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000328467 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24563 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:24563 "CG15432, cg15432" "IPR013865:Protein of unknown function DUF1754, eukaryotic" CG15432 11-Aug-17 DroID_v2017_08 Drer\fam32a - Cele\K01G5.8 Xtro\fam32a Mmus\Fam32a Hsap\FAM32A "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC00447 I -0.716213078 2.065140499 -0.397361645 1.424338214 0.637296688 0.106080053 FBgn0002224 l(3)68Ad lethal (3) 68Ad http://flybase.org/reports/FBgn0002224 FBgn0004711 gene - - - "l(3)68Ad', l(3)C117, D, l(3)D, l(3)68Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0267457 CR45807 - http://flybase.org/reports/FBgn0267457 non_protein_coding_gene - - - CR45807 - CR45807 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085581 CG41255 - http://flybase.org/reports/FBgn0085581 protein_coding_gene - - - CG41255 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003250 Rh4 Rhodopsin 4 http://flybase.org/reports/FBgn0003250 - protein_coding_gene G-protein coupled photoreceptor activity ; GO:0008020 | inferred from direct assay G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity G-protein coupled photoreceptor activity ; GO:0008020 | non-traceable author statement G-protein coupled photoreceptor activity ; GO:0008020 | traceable author statement "visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR000856 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000856 detection of UV ; GO:0009589 | traceable author statement phototransduction, UV ; GO:0007604 | traceable author statement phototransduction, UV ; GO:0007604 | non-traceable author statement phototransduction, UV ; GO:0007604 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity phototransduction ; GO:0007602 | non-traceable author statement" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000856, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "Rh4, rh4, CG9668, Rh, FBgn0003250, DMELRH4, Dm Rh4, RH4" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000856:Opsin RH3/RH4, IPR017452:GPCR, rhodopsin-like, 7TM, IPR027430:Visual pigments (opsins) retinal binding site" CG9668 11-Aug-17 DroID_v2017_08 "Drer\opn4xb, Drer\rgra, Drer\opn1mw3, Drer\opn6b, Drer\opn4xa, Drer\valopb, Drer\rho, Drer\opn4a, Drer\opn6a, Drer\opn1mw1, Drer\tmtops3a, Drer\parapinopsinb, Drer\opn7a, Drer\opn7c, Drer\valopa, Drer\opn3, Drer\parietopsin, Drer\exorh, Drer\rrh, Drer\opn9, Drer\opn1sw1, Drer\opn8b, Drer\opn1lw1, Drer\opn4.1, Drer\opn7b, Drer\opn1sw2, Drer\rhol, Drer\opn7d, Drer\opn4b, Drer\opn8c, Drer\tmtops3b, Drer\tmtopsb, Drer\tmtops2b, Drer\rgrb, Drer\tmtops2a, Drer\opn1mw4, Drer\opn1lw2, Drer\opn5" - "Cele\nmur-3, Cele\sro-1" "Xtro\LOC100485437, Xtro\tmtops.2, Xtro\tmtops, Xtro\LOC100485989, Xtro\LOC100124934, Xtro\rho, Xtro\opn1lw, Xtro\rrh, Xtro\opn1sw, Xtro\opn5" "Mmus\Opn1mw, Mmus\Opn5, Mmus\Rrh, Mmus\Opn1sw, Mmus\Opn4, Mmus\Rgr, Mmus\Rho, Mmus\Opn3" "Hsap\RGR, Hsap\OPN1MW3, Hsap\OPN3, Hsap\RRH, Hsap\OPN4, Hsap\RHO, Hsap\OPN5, Hsap\OPN1MW2, Hsap\OPN1LW, Hsap\OPN1MW, Hsap\OPN1SW" " adult stage , pupal stage | late , larval stage " " eye

, adult head

, Bolwig's organ

, photoreceptor cell R7

" adult stage " photoreceptor cell R1..6

{ 0 ninaE- } , photoreceptor cell R1--6

, photoreceptor cell R7 | presumptive

" "viable,fertile" FBgn0051200 CG31200 - http://flybase.org/reports/FBgn0051200 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "SPH169, CG17837, CG31200" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG31200 11-Aug-17 DroID_v2017_08 - - - - - Hsap\PAMR1 viable FBgn0261816 CG42758 - http://flybase.org/reports/FBgn0261816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42758, CG13479" - CG42758 11-Aug-17 DroID_v2017_08 - - - - - Hsap\KRTAP9-6 FBgn0023062 l(1)2Dk lethal (1) 2Dk http://flybase.org/reports/FBgn0023062 - gene - - - "1200B2, l(1)2Dk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002185 l(3)62Bi lethal (3) 62Bi http://flybase.org/reports/FBgn0002185 - gene - - - "dre6, rbd, l(3)dre6, l(3)62Bi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,heat sensitive,some die during pharate adult stage" FBgn0261436 DhpD Dihydropterin deaminase http://flybase.org/reports/FBgn0261436 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR014311 dihydropterin deaminase activity ; GO:0004153 | inferred from direct assay guanine deaminase activity ; GO:0008892 | inferred from direct assay guanine catabolic process ; GO:0006147 | inferred from electronic annotation with InterPro:IPR014311 dihydropteridine metabolic process ; GO:0051067 | inferred from mutant phenotype guanine metabolic process ; GO:0046098 | inferred from mutant phenotype dihydropteridine metabolic process ; GO:0051067 | inferred from direct assay eye pigment biosynthetic process ; GO:0006726 | inferred from mutant phenotype - "DhpD, CG18143" "IPR006680:Amidohydrolase-related, IPR014311:Guanine deaminase, IPR011059:Metal-dependent hydrolase, composite domain, IPR032466:Metal-dependent hydrolase" CG18143 11-Aug-17 DroID_v2017_08 Drer\gda Scer\GUD1 Cele\cpin-1 Xtro\gda Mmus\Gda Hsap\GDA eye color defective pigment cell FBgn0046648 anon-38D.18 anon-38D.18 http://flybase.org/reports/FBgn0046648 gene - - - "38D.18, anon-38D.18" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265156 CR44225 - http://flybase.org/reports/FBgn0265156 non_protein_coding_gene - - - CR44225 - CR44225 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065374 l(2)SH1685 lethal (2) SH1685 http://flybase.org/reports/FBgn0065374 gene - - - "l(2)SH1685, l(2)SH2 1685" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265740 CR44547 - http://flybase.org/reports/FBgn0265740 non_protein_coding_gene - - - "CR44547, lincRNA.502" - CR44547 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266949 CR45400 - http://flybase.org/reports/FBgn0266949 non_protein_coding_gene - - - CR45400 - CR45400 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010896 l(3)06658 lethal (3) 06658 http://flybase.org/reports/FBgn0010896 - gene - - - l(3)06658 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030984 tgy twiggy http://flybase.org/reports/FBgn0030984 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 "CG7440, tgy, dC1GalT5, Tgy" IPR003378:Fringe-like CG7440 11-Aug-17 DroID_v2017_08 "Drer\LOC564281, Drer\si:dkey-202e17.1, Drer\c1galt1a, Drer\c1galt1c1, Drer\c1galt1b" - "Cele\C38H2.2, Cele\bus-4, Cele\T09E11.12, Cele\W09D10.5, Cele\Y38C1AB.5, Cele\F37A4.3, Cele\E03H4.3, Cele\F56H6.1, Cele\C17A2.3, Cele\C02H6.1, Cele\Y38C1AB.1, Cele\C16D9.6" "Xtro\LOC100496837, Xtro\c1galt1" "Mmus\C1galt1c1, Mmus\C1galt1" "Hsap\C1GALT1, Hsap\C1GALT1C1" viable FBgn0053428 5SrRNA:CR33428 5SrRNA:CR33428 http://flybase.org/reports/FBgn0053428 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33428, 5SrRNA:CR33428" - CR33428 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266363 CG45011 - http://flybase.org/reports/FBgn0266363 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45011 IPR002350:Kazal domain CG45011 11-Aug-17 DroID_v2017_08 "Drer\tmeff2b, Drer\tmeff2a, Drer\tmeff1b, Drer\si:dkey-203a12.7" - Cele\ZK813.6 Xtro\tmeff1 "Mmus\Tmeff1, Mmus\Tmeff2" "Hsap\TMEFF1, Hsap\TMEFF2" FBgn0052441 CG32441 - http://flybase.org/reports/FBgn0052441 protein_coding_gene - - ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN001468346 "CG7783, CG32441" IPR029615:ER membrane protein complex subunit 10 CG32441 11-Aug-17 DroID_v2017_08 Drer\emc10 - Cele\Y43F8C.7 Xtro\emc10 Mmus\Emc10 Hsap\EMC10 "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0028191 l(3)S022930 lethal (3) S022930 http://flybase.org/reports/FBgn0028191 gene - - - "0229/30, l(3)S022930" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0065617 l(2)SH0817 lethal (2) SH0817 http://flybase.org/reports/FBgn0065617 gene - - - l(2)SH0817 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043490 en::onecut en::onecut http://flybase.org/reports/FBgn0043490 engineered_fusion_gene - - - en::onecut - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,eye photoreceptor cell,retina,optic lobe" FBgn0003698 thiv thickened veins http://flybase.org/reports/FBgn0003698 - gene - - - "thi, thiv" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,cold sensitive" FBgn0038735 CG4662 - http://flybase.org/reports/FBgn0038735 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - CG4662 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG4662 11-Aug-17 DroID_v2017_08 "Drer\micu1, Drer\micu2, Drer\micu3a, Drer\micu3b" - Cele\C56A3.6 "Xtro\micu3, Xtro\micu1, Xtro\micu2" "Mmus\Micu3, Mmus\Micu1, Mmus\Micu2" "Hsap\MICU1, Hsap\MICU2, Hsap\MICU3" "viable,fertile" FBgn0005352 su(Cy)r "suppressor of Curly, recessive" http://flybase.org/reports/FBgn0005352 - gene - - - "su(Cy)r, su(Cy)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016692 Pas Partial sevenless http://flybase.org/reports/FBgn0016692 - gene molecular_function ; GO:0003674 | no biological data available central nervous system development ; GO:0007417 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Pas - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "presumptive embryonic/larval central nervous system,rhabdomere" FBgn0045973 PdL72A3 PdL72A3 http://flybase.org/reports/FBgn0045973 gene - - - PdL72A3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014090 anon-31Ea anonymous at 31E-a http://flybase.org/reports/FBgn0014090 - gene - - - anon-31Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267136 CR45576 - http://flybase.org/reports/FBgn0267136 non_protein_coding_gene - - - "lincRNA.738, CR45576" - CR45576 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261592 RpS6 Ribosomal protein S6 http://flybase.org/reports/FBgn0261592 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001377, InterPro:IPR014401, InterPro:IPR018282 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000161291 cytoplasmic translation ; GO:0002181 | traceable author statement ribosomal small subunit biogenesis ; GO:0042274 | inferred from biological aspect of ancestor with PANTHER:PTN000161291 centrosome duplication ; GO:0051298 | inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement" ribosome ; GO:0005840 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "RpS6, CG10944, M(1)7BC, M(1)7C, S6, DS6, air8, rps6, pp30, rpS6, air[8], l(1)air[8], l(1)air8, hen, l(1)hen, anon-WO02059370.61, RPS6, Rps6, (Rp)S6, Rp S6" "IPR018282:Ribosomal protein S6e, conserved site, IPR001377:Ribosomal protein S6e, IPR014401:Ribosomal protein S6, eukaryotic" CG10944 11-Aug-17 DroID_v2017_08 "Drer\rps6, Drer\zgc:112083, Drer\hinfp" "Scer\RPS6A, Scer\RPS6B" "Cele\rps-6, Cele\hinf-1" "Xtro\hinfp, Xtro\rps6" "Mmus\Hinfp, Mmus\Rps6" Hsap\RPS6 embryonic stage -- adult stage DRSC18712 EK -1.315846862 -1.054685785 0.72029246 -3.624350145 1.87134093 4.108212097 FBgn0014896 anon-10Ac anon-10Ac http://flybase.org/reports/FBgn0014896 - gene - - - anon-10Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260311 GSd477 - http://flybase.org/reports/FBgn0260311 gene - - - GSd477 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028139 l(3)S048301a lethal (3) S048301a http://flybase.org/reports/FBgn0028139 gene - - - "0483/01, l(3)S048301, l(3)S048301a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0067372 l(2)NC14 lethal (2) NC14 http://flybase.org/reports/FBgn0067372 gene - - - l(2)NC14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265878 CR44667 - http://flybase.org/reports/FBgn0265878 non_protein_coding_gene - - - "CR44667, lincRNA.367" - CR44667 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063384 snoRNA:U29:54Eb snoRNA:U29:54Eb http://flybase.org/reports/FBgn0063384 snoRNA_gene - - - "U29snoRNA, CR32890, snoRNA:U29:54Eb, DmSnR71a" - CR32890 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015029 CU61 Cible d'Ubx 61 http://flybase.org/reports/FBgn0015029 - gene - - - "61, Cu61, CU61" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033547 CG12935 - http://flybase.org/reports/FBgn0033547 protein_coding_gene - nervous system development ; GO:0007399 | inferred from mutant phenotype - CG12935 IPR026100:Transmembrane protein 223 CG12935 11-Aug-17 DroID_v2017_08 Drer\tmem223 - - Xtro\tmem223 Mmus\Tmem223 Hsap\TMEM223 viable DRSC07025 K -0.768590933 0.27342169 0.519999025 -0.233746873 1.771573807 1.230042146 FBgn0066319 24D1 24D1 http://flybase.org/reports/FBgn0066319 gene - - - 24D1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023492 Mst78D Mst78D http://flybase.org/reports/FBgn0023492 - gene - - - Mst78D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259850 Su(Ste):CR42419 Su(Ste):CR42419 http://flybase.org/reports/FBgn0259850 non_protein_coding_gene - - - "Su(Ste):CR42419, CR42419" - CR42419 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261974 snoRNA:Or-CD9b - http://flybase.org/reports/FBgn0261974 snoRNA_gene - - nucleoplasm ; GO:0005654 | inferred from direct assay "CR42805, DmOr_cd9b snoRNA, CR34567, snoRNA:Or-CD9b, orphan CD9b, snoRNA:Or-cd9b, CR34101, snmRNA:60Cb, Dmsnm60b, snm60, DmOrC/D_9b, Snm60b" - CR42805 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034827 Klp59D Kinesin-like protein at 59D http://flybase.org/reports/FBgn0034827 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 regulation of motile cilium assembly ; GO:1905503 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "KLP59D, DmKlp59D, CG12192, Klp59D, KIF2A/B/C" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12192 11-Aug-17 DroID_v2017_08 "Drer\zgc:103670, Drer\kif2c" Scer\KIP3 Cele\klp-7 "Xtro\kif2c, Xtro\kif2a" "Mmus\Kif24, Mmus\Kif2b, Mmus\Kif2c, Mmus\Kif2a" "Hsap\KIF2A, Hsap\KIF2B, Hsap\KIF24, Hsap\KIF2C" viable FBgn0082372 EP2182 EP2182 http://flybase.org/reports/FBgn0082372 gene - - - EP2182 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male,embryonic/larval salivary gland" FBgn0265983 CR44762 - http://flybase.org/reports/FBgn0265983 non_protein_coding_gene - - - CR44762 - CR44762 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028999 nerfin-1 nervous fingers 1 http://flybase.org/reports/FBgn0028999 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype - "CG13906, nerfin-1, Nerfin-1, Nerfin, nerfin" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG13906 11-Aug-17 DroID_v2017_08 "Drer\insm1b, Drer\insm1a" - Cele\egl-46 Xtro\insm2 "Mmus\Insm1, Mmus\Insm2" "Hsap\INSM2, Hsap\ZNF7, Hsap\ZNF707, Hsap\INSM1" "viable,lethal - all die before end of pupal stage,some die during pupal stage" "longitudinal connective,anterior commissure,posterior commissure,pCC neuron,intermediate longitudinal fascicle,lateral longitudinal fascicle,medial longitudinal fascicle" FBgn0266934 CR45385 - http://flybase.org/reports/FBgn0266934 pseudogene_attribute - - - CR45385 - CR45385 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002240 l(3)68Cb lethal (3) 68Cb http://flybase.org/reports/FBgn0002240 - gene - - - "l(3)C605, l(3)68Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,recessive,lethal" FBgn0262761 Mst77Y-12 Male-specific transcript 77Y 12 http://flybase.org/reports/FBgn0262761 nuclear_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F "Mst77Y-12, Mst77Y-12a" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038001 CG17404 - http://flybase.org/reports/FBgn0038001 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP149, CG17404" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG17404 11-Aug-17 DroID_v2017_08 "Drer\st14b, Drer\prss59.2" - "Cele\svh-1, Cele\try-3" - "Mmus\2210010C04Rik, Mmus\Cfd, Mmus\Ovch2, Mmus\Try5, Mmus\Egfbp2, Mmus\Prss2" "Hsap\PRSS3, Hsap\OVCH1, Hsap\CFD, Hsap\OVCH2, Hsap\KLK6" viable DRSC15234 E 0.076363876 0.484088478 1.428018162 1.882274061 0.161500743 -0.068919954 FBgn0028638 ifm(2)RU4 indirect flight muscle (2) RU4 http://flybase.org/reports/FBgn0028638 gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay ifm(2)RU4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,flight defective,fertile,viable" "wing,dorsal medial muscle,dorsal medial muscle & myofibril" FBgn0261732 EC2374 - http://flybase.org/reports/FBgn0261732 gene - - - EC2374 - - 11-Aug-17 DroID_v2017_08 - - - - - - "some die during embryonic stage,lethal - all die before end of embryonic stage" FBgn0052945 CG32945 - http://flybase.org/reports/FBgn0052945 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32945 - CG32945 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262064 EG165 - http://flybase.org/reports/FBgn0262064 gene - - - EG165 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065813 l(2)SH0382 lethal (2) SH0382 http://flybase.org/reports/FBgn0065813 gene - - - "l(2)SH0382, l(2)SH2 0382" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261258 rgn regeneration http://flybase.org/reports/FBgn0261258 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 tissue regeneration ; GO:0042246 | inferred from expression pattern inferred from mutant phenotype - "l(3)00534, rgn, CG6014, BcDNA:GH11973" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG6014 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-28d5.8, Drer\si:ch211-170d8.8, Drer\si:dkey-88n24.9, Drer\si:dkey-81n2.1, Drer\lca5, Drer\si:dkey-28d5.14, Drer\si:dkey-88n24.10, Drer\si:dkey-28d5.13, Drer\si:ch211-282j17.3, Drer\si:dkey-241l7.3, Drer\LOC100000851, Drer\si:ch211-225k7.6, Drer\si:dkey-83f18.10, Drer\si:dkey-83f18.7, Drer\si:ch211-282j17.7, Drer\si:dkey-81n2.2, Drer\si:ch211-272h9.3, Drer\si:ch211-225k7.4, Drer\LOC101882781, Drer\si:dkey-28d5.10, Drer\si:dkey-28d5.12, Drer\si:ch211-63p21.4, Drer\si:ch211-225k7.2, Drer\si:dkey-83f18.3, Drer\si:dkey-88n24.7, Drer\si:dkey-192d15.3, Drer\si:dkey-83f18.9, Drer\si:dkey-241l7.5, Drer\si:dkey-88n24.6, Drer\si:ch73-335d12.2, Drer\si:ch211-193e13.5, Drer\zgc:194252, Drer\si:dkey-28d5.4, Drer\si:ch211-225k7.5, Drer\si:dkey-241l7.6, Drer\si:ch211-282j17.8, Drer\mns1, Drer\si:dkey-83f18.11, Drer\zgc:162060, Drer\si:dkey-26c10.5, Drer\si:ch211-282j17.11, Drer\si:dkey-28d5.9, Drer\si:ch211-282j17.10, Drer\si:dkey-88n24.8, Drer\si:ch211-282j17.1, Drer\si:dkey-83f18.5" - "Cele\clec-52, Cele\clec-22, Cele\clec-24, Cele\clec-53, Cele\clec-196, Cele\clec-25, Cele\clec-146, Cele\clec-51" Xtro\LOC100170489 "Mmus\Klrg1, Mmus\Clec2h, Mmus\Clec12a, Mmus\Klrb1f, Mmus\Klrb1a, Mmus\Reg3g, Mmus\Clec2f, Mmus\Clec7a, Mmus\Klra8, Mmus\Klrb1c, Mmus\Klrg2, Mmus\Clec2d, Mmus\Klra6, Mmus\Reg3d, Mmus\Klra17, Mmus\Clec2j, Mmus\Klrc2, Mmus\Reg4, Mmus\Klri1, Mmus\Klrb1b, Mmus\Clec2l, Mmus\Clec9a, Mmus\Clec1a, Mmus\Reg1, Mmus\Clec2e, Mmus\Klrd1, Mmus\Olr1, Mmus\4922502D21Rik, Mmus\Clec12b, Mmus\Cd69, Mmus\Klra7, Mmus\Reg2, Mmus\Klrc3, Mmus\Klra2, Mmus\Klrb1, Mmus\Klre1, Mmus\Clec5a, Mmus\Klrc1, Mmus\Klra3, Mmus\Klra4, Mmus\Clec2g, Mmus\Klra10, Mmus\Klra9, Mmus\Clec2i, Mmus\Klri2, Mmus\Klra1, Mmus\Gm156, Mmus\Klra5, Mmus\Clec1b, Mmus\Reg3b, Mmus\Klrk1" "Hsap\KLRF1, Hsap\REG3A, Hsap\CLEC9A, Hsap\KLRC1, Hsap\REG1B, Hsap\FCER2, Hsap\CD69, Hsap\REG4, Hsap\CLECL1, Hsap\CLEC1B, Hsap\MRC2, Hsap\COLEC12, Hsap\MRC1, Hsap\KLRF2, Hsap\KLRC4-KLRK1, Hsap\CLEC2L, Hsap\CLEC2D, Hsap\CLEC12B, Hsap\BCAN, Hsap\KLRC3, Hsap\KLRG2, Hsap\KLRD1, Hsap\OLR1, Hsap\CLEC1A, Hsap\CLEC2A, Hsap\KLRB1, Hsap\REG1A, Hsap\NCAN, Hsap\KLRK1, Hsap\KLRC4, Hsap\REG3G, Hsap\CLEC2B, Hsap\KLRG1, Hsap\CLEC12A, Hsap\CLEC5A, Hsap\CLEC7A, Hsap\KLRC2" FBgn0025383 CG14780 - http://flybase.org/reports/FBgn0025383 - protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP95, EG:80H7.3, CG14780" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG14780 11-Aug-17 DroID_v2017_08 "Drer\gzmk, Drer\LOC100004427, Drer\zgc:165423, Drer\zgc:92313, Drer\si:dkeyp-93a5.3, Drer\si:dkey-16l2.17, Drer\gzma, Drer\cfd, Drer\zgc:163079, Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.8, Drer\ovch1, Drer\gzm3, Drer\si:ch211-165b19.9" - "Cele\try-6, Cele\try-1" - "Mmus\Prss2, Mmus\Klk15, Mmus\Klk9" "Hsap\KLK15, Hsap\KLK9" viable FBgn0037610 CG8043 - http://flybase.org/reports/FBgn0037610 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:27302 iron-sulfur cluster assembly ; GO:0016226 | inferred from biological aspect of ancestor with PANTHER:PTN000503456 iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with SGD:S000003883 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000503457 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with SGD:S000003883 "CG8043, Iba57" "IPR006222:Glycine cleavage T-protein-like, N-terminal, IPR013977:Glycine cleavage T-protein, C-terminal barrel domain, IPR017703:YgfZ/GcvT conserved site" CG8043 11-Aug-17 DroID_v2017_08 Drer\iba57 Scer\IBA57 Cele\F39H2.3 Xtro\iba57 Mmus\Iba57 Hsap\IBA57 "partially lethal - majority die,some die during pupal stage,locomotor rhythm defective" FBgn0033279 CG2291 - http://flybase.org/reports/FBgn0033279 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT16234, CG2291" - CG2291 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015359 CG2034 - http://flybase.org/reports/FBgn0015359 - protein_coding_gene - - Elongator holoenzyme complex ; GO:0033588 | inferred from electronic annotation with InterPro:IPR019519 "anon-i1, CG2034" IPR019519:Elongator complex protein 5 CG2034 11-Aug-17 DroID_v2017_08 Drer\elp5 - - - Mmus\Elp5 Hsap\ELP5 viable embryonic/larval hemocyte | third instar larval stage FBgn0034909 CG4797 - http://flybase.org/reports/FBgn0034909 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG4797 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG4797 11-Aug-17 DroID_v2017_08 "Drer\slc2a12, Drer\slc2a6, Drer\slc2a8, Drer\soat1, Drer\soat2, Drer\slc2a10, Drer\slc2a13b, Drer\LOC101882338" "Scer\HXT11, Scer\HXT14, Scer\ITR1, Scer\YDR387C, Scer\VBA1, Scer\SGE1, Scer\MAL11, Scer\VBA3, Scer\VBA5, Scer\YDL199C, Scer\HXT7, Scer\YMR279C, Scer\HXT6, Scer\HXT3, Scer\HXT8, Scer\SNF3, Scer\MAL31, Scer\GAL2, Scer\HXT16, Scer\VBA4, Scer\ENB1, Scer\AZR1, Scer\GEX1, Scer\HXT4, Scer\HXT5, Scer\YFL040W, Scer\GEX2, Scer\HXT2, Scer\HXT9, Scer\VBA2, Scer\HXT13, Scer\HXT15, Scer\HXT10, Scer\HXT17, Scer\MPH2, Scer\ITR2, Scer\RGT2, Scer\HXT1, Scer\MPH3, Scer\STL1, Scer\ATR1" Cele\mboa-1 "Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a12, Xtro\soat1, Xtro\slc2a6, Xtro\soat2" "Mmus\Slc2a6, Mmus\Soat1, Mmus\Soat2, Mmus\Slc2a10, Mmus\Slc2a12, Mmus\Slc2a8, Mmus\Slc2a13" "Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SOAT2, Hsap\SLC2A12, Hsap\SLC2A8, Hsap\SLC2A10, Hsap\SOAT1" "viable,fertile,partially lethal - majority die,visible" mesothoracic tergum FBgn0036474 Or71a Odorant receptor 71a http://flybase.org/reports/FBgn0036474 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "OR71a, Or71c, 71a, DOR14, 71B.1, CG17871, Or71a, or71a" "IPR004117:Olfactory receptor, insect" CG17871 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019770 l(1)48B lethal (1) 48B http://flybase.org/reports/FBgn0019770 - gene - - - l(1)48B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019638 ApII Apurinic/apyrimidinic endonuclease II http://flybase.org/reports/FBgn0019638 - gene DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906 | inferred from direct assay DNA repair ; GO:0006281 | inferred from direct assay - ApII - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002647 mapP midgut amylase pattern PMG http://flybase.org/reports/FBgn0002647 - gene - - - "map, map-PMG, mapP" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034243 Ns2 Nucleostemin 2 http://flybase.org/reports/FBgn0034243 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006073, InterPro:IPR030378 GTPase activity ; GO:0003924 | inferred from direct assay" positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype nucleolus ; GO:0005730 | colocalizes_with inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleoplasm ; GO:0005654 | colocalizes_with inferred from direct assay "CG6501, ns2, Ngp, dmNS2, NS2, Ngp1, Ns2" "IPR030378:Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR006073:GTP binding domain, IPR012971:Nucleolar GTP-binding protein 2, N-terminal domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024929:Nucleolar GTP-binding protein 2, IPR023179:GTP-binding protein, orthogonal bundle domain" CG6501 11-Aug-17 DroID_v2017_08 Drer\gnl2 Scer\NOG2 Cele\ngp-1 Xtro\gnl2 Mmus\Gnl2 Hsap\GNL2 "cell lethalcell lethal,recessive,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal,visible,long lived" "wing disc,somatic clone,eye" DRSC06993 E -1.237858552 0.866919167 2.358023133 -0.671870781 -0.299468794 1.283393864 FBgn0002645 Map205 Microtubule-associated protein 205 http://flybase.org/reports/FBgn0002645 - protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype inferred from genetic interaction with polo centrosome organization ; GO:0051297 | inferred from mutant phenotype spindle ; GO:0005819 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity midbody ; GO:0030496 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "205K MAP, CG1483, MAP4, 205-kDa MAP, MAP205, 205kDa MAP, 205kD MAP, Map205, map205" - CG1483 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0002335 l(3)87Bc lethal (3) 87Bc http://flybase.org/reports/FBgn0002335 - gene - - - "ck15, l(3)ck15, l(3)87Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0011892 tRNA:Lys-CTT-1-6 transfer RNA:Lysine-CTT 1-6 http://flybase.org/reports/FBgn0011892 "FBgn0003796, FBgn0011886, FBgn0011900, FBgn0050300, FBgn0060180" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "tRNA[Lys][[2]], AE002778.trna4-LysCTT, tRNA:K2, tRNA:K4, tRNA:K:CTT:AE002778-d, CR30300, tRNA:lys2:42Ea, tRNAlys, chr2R.trna91-LysCTT, tRNA-Lys-CTT-1-6, tRNA:Lys-CTT-1-6, tRNA:K2:42Ea, AAG" - CR30300 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026395 Or23a Odorant receptor 23a http://flybase.org/reports/FBgn0026395 - protein_coding_gene "transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | non-traceable author statement inferred by curator from GO:0004888,GO:0007608" detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay sensory perception of smell ; GO:0007608 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred from expression pattern dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from direct assay "23a, DOR64, DOR64, AN5, CG9880, 23A.1, Dor64, AN5, dor64, DOR23A.1, Or64, Or23A.1, Or23a, or23a" "IPR004117:Olfactory receptor, insect" CG9880 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " sensory neuron &&of maxillary palpus

, sensory neuron &&of antennal segment 3

" FBgn0036496 CG7804 - http://flybase.org/reports/FBgn0036496 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg7804, CG7804" IPR000504:RNA recognition motif domain CG7804 11-Aug-17 DroID_v2017_08 "Drer\tardbp, Drer\tardbpl" Scer\DDR48 "Cele\sqd-1, Cele\tdp-1" Xtro\tardbp Mmus\Tardbp Hsap\TARDBP "viable,partially lethal - majority die,some die during pupal stage" FBgn0046636 anon-38D.9 anon-38D.9 http://flybase.org/reports/FBgn0046636 gene - - - "38D.9, anon-38D.9" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017562 Oef2 oe1 binding factor 2 http://flybase.org/reports/FBgn0017562 - gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "OEF2, Oef2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010564 l(2)04012a lethal (2) 04012a http://flybase.org/reports/FBgn0010564 - gene - - - "l(2)04012, 4012, l(2)04012a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001625 l(1)dn2 lethal (1) discs normal 2 http://flybase.org/reports/FBgn0001625 - gene - - - "l(1)d.norm.-2, l(1)dn2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0039212 Syx18 Syntaxin 18 http://flybase.org/reports/FBgn0039212 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with Syx17 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNARE binding ; GO:0000149 | inferred from sequence or structural similarity with Syx17 "retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000409677 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000409677 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype" cell cortex ; GO:0005938 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000409677 SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000409677 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with Syx17 "DmSyx18, Ufe1/Syntaxin 18, Dm Ufe1, CG13626, Syx18, Syx, gtx" "IPR000727:Target SNARE coiled-coil homology domain, IPR019529:SNARE-complex protein Syntaxin-18, N-terminal" CG13626 11-Aug-17 DroID_v2017_08 "Drer\cox5aa, Drer\stx18, Drer\cox5ab" Scer\UFE1 "Cele\syx-18, Cele\cco-2" "Xtro\stx18, Xtro\cox5a" "Mmus\Stx18, Mmus\Cox5a" Hsap\STX18 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective,neurophysiology defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,visible,partially lethal - majority die,some die during pupal stage" "NMJ bouton,endomembrane system & embryonic/larval somatic muscle,embryonic/larval somatic muscle,subsynaptic reticulum,neuromuscular junction,embryonic/larval neuromuscular junction,subsynaptic reticulum | ectopicC57,mesothoracic tergum" DRSC14628 I 4.24921079 0.79566397 1.14461768 -0.997504847 -0.23413268 -0.447899628 FBgn0000779 fs(1)A1459 female sterile (1) A1459 http://flybase.org/reports/FBgn0000779 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)1459, fs(1)M23, fs(1)K499, fs(1)M2, fs(1)A1459" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,female sterile,recessive,heat sensitive,non-rescuable maternal effect" "gastrula embryo,maternal effect,blastoderm embryo" FBgn0028475 Hrd3 HMG-coA reductase degradation 3 http://flybase.org/reports/FBgn0028475 protein_coding_gene - - - "BcDNA:LD23587, HRD3, CG10221, Hrd3" IPR006597:Sel1-like repeat CG10221 11-Aug-17 DroID_v2017_08 "Drer\LOC559843, Drer\sel1l, Drer\lrp2bp, Drer\LOC101886164, Drer\zgc:158257" "Scer\ACK1, Scer\SHC1, Scer\SKT5, Scer\HRD3" Cele\sel-1 "Xtro\lrp2bp, Xtro\sel1l3, Xtro\sel1l" "Mmus\Lrp2bp, Mmus\Sel1l2, Mmus\0610009O20Rik, Mmus\Sel1l3, Mmus\Sel1l" "Hsap\SEL1L3, Hsap\LRP2BP, Hsap\SEL1L2, Hsap\SEL1L, Hsap\KIAA0141" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0030099 CG12056 - http://flybase.org/reports/FBgn0030099 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000031542 - endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 CG12056 IPR001199:Cytochrome b5-like heme/steroid binding domain CG12056 11-Aug-17 DroID_v2017_08 "Drer\cyb5d2, Drer\nenf" - Cele\tag-131 "Xtro\cyb5d2, Xtro\nenf" "Mmus\Nenf, Mmus\Cyb5d2" "Hsap\NENF, Hsap\CYB5D2" FBgn0000490 dpp decapentaplegic http://flybase.org/reports/FBgn0000490 FBgn0010065 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR001111, InterPro:IPR001839, InterPro:IPR017948 transforming growth factor beta receptor binding ; GO:0005160 | non-traceable author statement morphogen activity ; GO:0016015 | non-traceable author statement collagen binding ; GO:0005518 | inferred from direct assay transforming growth factor beta receptor binding ; GO:0005160 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 cytokine activity ; GO:0005125 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P07713 heparin binding ; GO:0008201 | inferred from direct assay morphogen activity ; GO:0016015 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with dally protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:P54631" "anterior Malpighian tubule=0061327; hindgut morphogenesis=0007442; cell shape=0008360; apoptotic process=0042981;germ cell=0007281; genital disc=0035215; female germ-line stem cell population maintenance=0036099; cardioblast differentiation=0010002; negative .. salivary gland boundary specification=0045705; cell fate specification=0001708; amnioserosa formation=0007378; wing disc pattern formation=0035222; zygotic specification of dorsal/ventral axis=0007352; imaginal disc pattern formation=0007447; negative .. gene expression=0010629 | inferred from expression pattern open tracheal system=0007424; spectrosome organization=0030721; wing disc pattern formation=0035222; with UniProtKB:P27091 heart=0007507; imaginal disc=0007444; dorsal closure=000739; hindgut morphogenesis=0048619; wing disc proximal/distal pattern formation=0007473; genital disc sexually dimorphic=0035263; imaginal disc pattern formation=0007447; germ-line stem cell division=0042078; progression of morphogenetic furrow involved in compound eye morphogenesis=0007458; labial disc=0035217; branched duct epithelial cell fate determination, open tracheal system=0046845; heart=0007507; BMP signaling pathway involved in Malpighian tubule cell chemotaxis=0061353; genital disc anterior/posterior pattern formation=0035224 | inferred from expression pattern dorsal/ventral axis specification=0009950; ovarian follicle cell=0030707; dorsal closure=0007391; imaginal disc-derived wing vein morphogenesis=0008586; chorion-containing eggshell formation=0007304; hemocyte=0007516; anterior/posterior pattern specification, imaginal disc=0007448; zygotic specification of dorsal/ventral axis=0007352; leg disc proximal/distal pattern formation=0007479; SMAD protein signal transduction=0060395; cell differentiation=0045595; mesoderm=0007498; dorsal appendage formation=0046843; eye-antennal disc morphogenesis=0007455; larval lymph gland hemocyte differentiation=0035168; dorsal closure=0007391 | with bsk cell fate determination=0001709; stem cell population maintenance=0019827; BMP signaling pathway=0030509; nurse cell apoptotic process=0045476; compound eye morphogenesis=0001745; imaginal disc-derived wing vein specification=0007474; cell fate specification=0001708; dorsal closure, leading edge cell fate determination=0007393; epithelial cell migration, open tracheal system=0007427; imaginal disc-derived wing vein specification=0007474; hindgut morphogenesis=0007442; maternal specification of dorsal/ventral axis, oocyte, soma encoded=0007313; open tracheal system=0007424; Malpighian tubule morphogenesis=0007443; pathway-restricted SMAD protein phosphorylation=0010862; germ-line stem cell population maintenance=0030718; imaginal disc growth=0007446; foregut morphogenesis=0007440;organ growth=0046620; germ cell migration=0008354; leg disc proximal/distal pattern formation=0007479; mesoderm=0007498; cell proliferation=0042127; imaginal disc-derived wing morphogenesis=0007476; ectoderm=0007398; germ-line stem cell division=0042078; fusion cell fate specification=0035156; male germ-line stem cell population maintenance=0036098; transforming growth factor beta receptor signaling pathway=0007179; muscle organ=0048636; .. MAPK cascade=0043408; cell proliferation=0008285; pericardial nephrocyte differentiation=0061320; lymph gland=0048542; gene expression=0010629; dorsal/ventral axis specification=0009950; amnioserosa formation=0007378; tube diameter, open tracheal system=0035158; BMP signaling pathway=0030509; anterior/posterior axis specification=0009948" cytoneme ; GO:0035230 | colocalizes_with inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay intracellular ; GO:0005622 | inferred from direct assay endosome ; GO:0005768 | colocalizes_with inferred from direct assay "dpp, Dpp, BMP, DPP, TGF-beta, TGFbeta, Dm-DPP, TGF-b, CG9885, l(2)k17036, l(2)10638, l(2)22Fa, shv, M(2)LS1, ho, blk, Tg, M(2)23AB, Hin-d, DPP-C, TGF-betagr;/SMAD" "IPR001111:TGF-beta, propeptide, IPR001839:Transforming growth factor-beta, C-terminal, IPR015615:Transforming growth factor-beta-related, IPR017948:Transforming growth factor beta, conserved site, IPR029034:Cystine-knot cytokine" CG9885 11-Aug-17 DroID_v2017_08 "Drer\gdf11, Drer\gdf2, Drer\gdf6a, Drer\gdf9, Drer\bmp6, Drer\amh, Drer\mstna, Drer\bmp8a, Drer\ndr2, Drer\inhbab, Drer\bmp16, Drer\bmp2b, Drer\lft1, Drer\inhbb, Drer\bmp2a, Drer\gdf10a, Drer\tgfb2l, Drer\bmp7b, Drer\bmp3, Drer\gdf7, Drer\bmp15, Drer\lft2, Drer\tgfb3, Drer\inha, Drer\bmp10, Drer\spaw, Drer\mstnb, Drer\bmp4, Drer\tgfb1b, Drer\gdf6b, Drer\gdf5, Drer\bmp7a, Drer\gdf3, Drer\bmp10l, Drer\tgfb1a, Drer\ndr1, Drer\admp, Drer\gdf10b, Drer\inhbaa, Drer\tgfb2, Drer\LOC100329520" - "Cele\daf-7, Cele\dbl-1, Cele\unc-129, Cele\tig-2" "Xtro\bmp6, Xtro\gdf11.1, Xtro\bmp15, Xtro\nodal5, Xtro\admp, Xtro\gdf7, Xtro\bmp8, Xtro\lefty, Xtro\bmp2, Xtro\nodal, Xtro\nodal, Xtro\bmp3, Xtro\bmp7.2, Xtro\gdf5, Xtro\bmp10, Xtro\nodal1, Xtro\gdf3, Xtro\nodal6, Xtro\inhbc.1, Xtro\bmp5, Xtro\mstn.1, Xtro\tgfb1, Xtro\gdf10, Xtro\gdf1, Xtro\inha, Xtro\tgfb2, Xtro\bmp7.1, Xtro\bmp4, Xtro\gdf2, Xtro\gdf9" "Mmus\Mstn, Mmus\Gdf7, Mmus\Bmp8b, Mmus\Inhbe, Mmus\Gdf9, Mmus\Inhbc, Mmus\Bmp4, Mmus\Gdf15, Mmus\Bmp6, Mmus\Lefty2, Mmus\Bmp2, Mmus\Lefty1, Mmus\Gdf3, Mmus\Gdf6, Mmus\Bmp5, Mmus\Inha, Mmus\Gdf2, Mmus\Amh, Mmus\Tgfb2, Mmus\Inhbb, Mmus\Gdf11, Mmus\Nodal, Mmus\Tgfb1, Mmus\Bmp10, Mmus\Bmp15, Mmus\Gdf1, Mmus\Bmp3, Mmus\Bmp7, Mmus\Tgfb3, Mmus\Gdf5, Mmus\Gdf10, Mmus\Inhba, Mmus\Bmp8a" "Hsap\INHA, Hsap\BMP2, Hsap\GDF9, Hsap\INHBC, Hsap\GDF1, Hsap\LEFTY2, Hsap\MSTN, Hsap\BMP8A, Hsap\GDF5, Hsap\AMH, Hsap\LEFTY1, Hsap\GDF7, Hsap\NODAL, Hsap\BMP3, Hsap\GDF11, Hsap\BMP4, Hsap\BMP5, Hsap\GDF15, Hsap\GDF2, Hsap\TGFB3, Hsap\BMP10, Hsap\TGFB1, Hsap\BMP6, Hsap\BMP15, Hsap\GDF6, Hsap\BMP8B, Hsap\INHBA, Hsap\GDF10, Hsap\BMP7, Hsap\INHBE, Hsap\TGFB2, Hsap\GDF3, Hsap\INHBB" " larval stage | third instar , embryonic stage | cellular blastoderm , embryonic stage | stage 14 , embryonic stage | stage 13 , embryonic stage , embryonic stage | mid-late , prepupal stage , embryonic stage | stage 11-17 , larval stage | first instar , pupal stage | >=18-20 hr , embryonic stage | stage 11 , prepupal stage | 6-9 hr , embryonic stage | mid &late , embryonic stage | stage 12 , embryonic stage | stage 13-16 , larval stage " " ventral thoracic disc | restricted

, dorsal ectoderm anlage

, dorsal mesothoracic disc | restricted

, male genital disc | restricted

, embryonic/larval esophagus

, embryonic brain

, visceral mesoderm &&of parasegment 8--12

, ventral mesothoracic disc | resticted

, parasegment 7

{ + abd-AM1 } , midgut constriction 3

, female genital disc | restricted

, midgut constriction 2

, imaginal disc primordium

, wing vein | primordium

, eye-antennal disc | restricted

, midgut

{ v dpps21/dpps4 } , parasegment 7 visceral mesoderm

{ - Ubx1 } , thoracic segment

, dorsal mesothoracic disc | restriced

, procephalic segment

, foregut

{ + abd-AM1 } , larval labral segment sense organ

, visceral mesoderm &&of parasegment 7

, larval brain | restricted

, gastric caecum

, dorsal mesothoracic disc | anterior/posterior compartment boundary

, embryonic/larval hindgut

, embryonic/larval foregut

{ - dpps21/dpps4 } , visceral mesoderm &&of parasegment 7--12

, embryonic/larval pharynx

" " embryonic stage | stage 14-17 , larval stage | third instar , embryonic stage | mid-late , embryonic stage | stage 16-17 , embryonic stage | stage 12 " " midgut constriction 2

, morphogenetic furrow

, parasegment 3,8..12 visceral mesoderm

{ + Ubxhs.PU, Ubx-, abd-A- } , parasegment 7 &&of endoderm

, visceral mesoderm &&of parasegment 2--12

, parasegment 7 &&of visceral mesoderm

, visceral mesoderm &&of parasegment 7

, eye disc | ubiquitous

, parasegment 6..7 visceral mesoderm

{ + Ubxhs.PU } , dorsal mesothoracic disc | ubiquitous

, parasegment 3,6..7 visceral mesoderm

{ - Ubx6.28 } , parasegment 3..7 visceral mesoderm

{ + abd-AMX1 } , parasegment 3,6..12 visceral mesoderm

{ $ Ubx-, abd-A- } , ventral thoracic disc | ubiquitous

, dorsal mesothoracic disc | anterior posterior gradient

" "visible,recessive,lethal,some die during embryonic stage,dominant,short lived,RU486 conditional,circadian rhythm defective,heat sensitive,viable,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,wild-type,increased cell death,somatic clone,partially lethal - majority die,size defective,reduced,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,female fertile,increased cell number,immune response defective,conditional,homeotic,tumorigenic,female sterile,hyperplasia,decreased cell number" ",embryonic/first instar larval cuticle,wing vein,wing,unguis,leg,eye,antenna,medulla neuropil,ommatidium,embryonic dorsal epidermis,cephalopharyngeal skeleton,filzkorper,embryonic thorax,embryonic head,head,antennal disc,ventral thoracic disc,spermatogonium,ventral nerve cord commissure,longitudinal connective,frons,retina,morphogenetic furrow,eye-antennal disc,male genitalia,penis,gonopod thorn bristle,gonopod long bristle,dorsal appendage,mesothoracic extracoxal depressor muscle 66,submarginal cell,1st posterior cell,cephalic furrow,amnioserosa,vibrissae,maxillary palpus,rostral membrane,gena,adult head,sternite,clasper,female gonopod,follicle cell,tergite,embryonic epidermis,dil cell,crossvein,wing cell,anterior crossvein,dpphr4,germarium,female germline stem cell,embryonic abdomen,abdominal segment,chorion,egg operculum,egg,micropyle,embryonic head epidermis,embryonic optic lobe primordium,wing disc,cardial valve,alula,female analia,male terminalia,capitellum,tibia,femur,sex comb,arista,fourth segment of antenna,fifth segment of antenna,taste bristle,genital disc,imaginal disc,egg chamber,macrochaeta,microchaeta,scutum,anal plate,lateral plate,head capsule,haltere,crystal cell,posterior crossvein,embryonic gnathal segment,cardiogenic mesoderm,embryonic/larval lymph gland,cardioblast,embryonic optic lobe,mitotic domain 1,mitotic domain 3,mitotic domain 5,embryonic hindgut,embryonic large intestine,extended germ band embryo,cuticle,Bolwig organ,corpus cardiacum primordium,embryo,larval head,gastric caecum,embryonic/larval midgut,scutellar bristle,third segment of antenna,dorsal hair,tegula,supraalar bristle,secondary pigment cell,tertiary pigment cell,interommatidial bristle,wing margin bristle,embryonic anal pad,maxillary palp sense organ,antennal sense organ,gastric caecum primordium,midgut constriction,embryonic dorsal pouch primordium,male analia,pseudotrachea,dpphr56,germline cell,hub cell,genital disc primordium,labellum,scutellum,embryonic/larval cuticle,embryonic/larval foregut,embryonic/larval pericardial cell,mesoderm,embryonic/larval heart,hemocyte,plasmatocyte,lamellocyte,A1-7 dorsal oblique muscle 1,haltere disc,sensillum campaniformium of dorsal radius,sensillum campaniformium of proximal ventral radius,prescutum,vulva,dorsal double row,ventral double row,dorsal triple row,medial triple row,ventral triple row,terminalia,tracheocyte,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,eye disc,wing hair,germarium cap cell,stem cell fusome,male germline stem cell,primary spermatocyte,tracheal branch primordium,embryonic/larval tracheal system,germline cyst,oocyte,interfollicle cell,presumptive embryonic/larval tracheal system,embryonic/larval dorsal branch,embryonic anterior Malpighian tubule,zen.Kr.PF,twi.PGa,fat body/gonad primordium,epidermis,spermatocyte,primary gonial cell,spermatid,testis,wing disc |,embryonic/larval visceral branch,tracheal tip cell |,btl.PS,spiracular chamber,midgut,GMR.PF,subretinal glial cell,dorsal mesothoracic disc primordium,prothoracic leg,mesothoracic leg,metathoracic leg,dpp.blk1,visual primordium,labral segment,ovary,female germline cell,adult midgut precursor cell" DRSC00118 I 0.328255955 2.378687749 -0.31386119 0.123479339 -0.259937839 -0.103012015 FBgn0020182 Ddc::ftz Ddc::ftz http://flybase.org/reports/FBgn0020182 - engineered_fusion_gene - - - Ddc::ftz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019639 ApI Apurinic/apyrimidinic endonuclease I http://flybase.org/reports/FBgn0019639 - gene DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906 | inferred from direct assay DNA repair ; GO:0006281 | inferred from direct assay - ApI - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069069 20-51 20-51 http://flybase.org/reports/FBgn0069069 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 20-51 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" FBgn0266500 s-200 - http://flybase.org/reports/FBgn0266500 gene - - - s-200 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040026 CG17653 - http://flybase.org/reports/FBgn0040026 protein_coding_gene - - - CG17653 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032104 aust australin http://flybase.org/reports/FBgn0032104 protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay mitotic sister chromatid segregation ; GO:0000070 | inferred from biological aspect of ancestor with PANTHER:PTN001815752 male meiosis sister chromatid cohesion ; GO:0007065 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype chromosome passenger complex ; GO:0032133 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay meiotic spindle midzone ; GO:1990385 | colocalizes_with inferred from direct assay "CG17009, aust" IPR018867:Cell division protein borealin CG17009 11-Aug-17 DroID_v2017_08 "Drer\cdca9, Drer\cdca8" - - "Xtro\cdca8, Xtro\cdca9" Mmus\Cdca8 Hsap\CDCA8 "viable,visible,cytokinesis defective,male,meiotic cell cycle defective,male sterile" mesothoracic tergum FBgn0023178 Pdf Pigment-dispersing factor http://flybase.org/reports/FBgn0023178 "FBgn0044602, FBgn0044606, FBgn0047045" protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR009396 neuropeptide hormone activity ; GO:0005184 | non-traceable author statement receptor binding ; GO:0005102 | inferred from physical interaction with UniProtKB:Q9W4Y2 neuropeptide hormone activity ; GO:0005184 | traceable author statement "circadian sleep/wake cycle ; GO:0042745 | inferred from genetic interaction with ITP gravitaxis ; GO:0042332 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern circadian rhythm ; GO:0007623 | traceable author statement neuropeptide signaling pathway ; GO:0007218 | traceable author statement eclosion rhythm ; GO:0008062 | traceable author statement circadian rhythm ; GO:0007623 | inferred from mutant phenotype positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010579 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay circadian sleep/wake cycle ; GO:0042745 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from direct assay locomotor rhythm ; GO:0045475 | non-traceable author statement entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype regulation of circadian sleep/wake cycle ; GO:0042749 | inferred from mutant phenotype mating behavior ; GO:0007617 | inferred from mutant phenotype regulation of locomotor rhythm ; GO:1904059 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | traceable author statement positive regulation of circadian sleep/wake cycle, wakefulness ; GO:0010841 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from expression pattern circadian rhythm ; GO:0007623 | non-traceable author statement" extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred by curator from GO:0005184 "pdf, PDF, cPDH, PAP, PDH, Drm-PDH, Drm-pdf, Drm-PDF, CG6496, BcDNA:RH08487, anon-WO0140519.3, anon-WO0140519.261, Pdf" IPR009396:Pigment-dispersing hormone CG6496 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult head

larval stage | third instar " cell body &&of larval lateral neuron

, larval lateral neuron

" "locomotor rhythm defective,mating rhythm defective,mating defective,recessive,circadian rhythm defective,photoperiod response variant,behavior defective,gravitaxis defective,circadian behavior defective,body color defective,partially lethal - majority die,some die during pupal stage" "LNv neuron,LNd neuron,mesothoracic tergum" DRSC16786 K 0.958538982 -0.114084029 -0.66076399 -0.057835684 1.864466002 0.203631205 FBgn0028622 qsm quasimodo http://flybase.org/reports/FBgn0028622 protein_coding_gene - locomotor rhythm ; GO:0045475 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from sequence or structural similarity with dyl - "qsm, CG13432, l(2)k009920, EP2356, EP2587, CG13433, l(2)05510, lethal (2) 05510, L(2)05510, QSM" IPR001507:Zona pellucida domain CG13432 11-Aug-17 DroID_v2017_08 - - "Cele\cutl-2, Cele\T01D1.8, Cele\cutl-5, Cele\cut-1, Cele\cutl-14, Cele\cutl-28, Cele\cutl-10, Cele\cut-5, Cele\cutl-20, Cele\cutl-25, Cele\cutl-17, Cele\cutl-9, Cele\cutl-7, Cele\cutl-16, Cele\cutl-6, Cele\cutl-12, Cele\cutl-26, Cele\cutl-15, Cele\F46G11.6, Cele\cutl-1, Cele\cutl-29, Cele\cutl-24, Cele\cut-4, Cele\cutl-8, Cele\cutl-19, Cele\noah-1, Cele\cutl-3, Cele\cutl-13, Cele\cut-3, Cele\cutl-18, Cele\cutl-22, Cele\cutl-11, Cele\cut-6, Cele\dpy-1, Cele\cutl-4, Cele\ram-5" - - - "lethal,recessive,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,locomotor rhythm defective,neuroanatomy defective" "adult thorax,ommatidium,eye,embryonic/larval salivary gland,dorsocentral bristle,scutellar bristle,trichogen cell,tormogen cell,intersegmental nerve,anterior fascicle & synapse | supernumerary,embryonic/larval central nervous system,wing" DRSC06393 I -0.998993484 -1.853041451 -0.784492151 -0.266703295 0.316416831 0.206354582 FBgn0052405 Cpr65Av Cuticular protein 65Av http://flybase.org/reports/FBgn0052405 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG10461, BcDNA:RE31218, Cpr65Av, CG32405, DmelCpr65Av" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG32405 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0010774 Ref1 RNA and export factor binding protein 1 http://flybase.org/reports/FBgn0010774 FBgn0027857 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" nucleoplasm ; GO:0005654 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:19071 nucleus ; GO:0005634 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "ref1, REF1, CG1101, dmREF1, DmREF1, cg1101, l(3)02267, BcDNA:LD24793, Aly, ALY, Ref1, aly" "IPR025715:Chromatin target of PRMT1 protein, C-terminal, IPR000504:RNA recognition motif domain" CG1101 11-Aug-17 DroID_v2017_08 "Drer\poldip3, Drer\alyref" Scer\YRA1 "Cele\C02B10.4, Cele\Y37E11AL.9, Cele\aly-1, Cele\aly-2, Cele\R06C1.4, Cele\aly-3" "Xtro\poldip3, Xtro\alyref" "Mmus\Alyref2, Mmus\Gm4307, Mmus\Gm4305, Mmus\Gm21312, Mmus\Gm6763, Mmus\Gm4312, Mmus\Gm20765, Mmus\Gm4303, Mmus\Gm4302, Mmus\Gm21293, Mmus\Poldip3, Mmus\Alyref, Mmus\Gm8764, Mmus\Gm4340, Mmus\Gm21304, Mmus\Gm4301" "Hsap\ALYREF, Hsap\POLDIP3, Hsap\CSTF2T"

"lethal,recessive,viable,visible,planar polarity defective,female semi-sterile,female fertile" "trichogen cell,supernumerary" DRSC22387 IE 2.800958662 1.499724054 7.369790215 4.863691565 0.035585267 -0.082481817 FBgn0259830 ifm(2)RS14 indirect flight muscle (2) RS14 http://flybase.org/reports/FBgn0259830 gene - adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS14 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable indirect flight muscle FBgn0001711 l(1)ESHS32 lethal (1) ESHS32 http://flybase.org/reports/FBgn0001711 - gene - - - l(1)ESHS32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0064193 arbl arborless http://flybase.org/reports/FBgn0064193 gene - - - arbl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085486 CG34457 - http://flybase.org/reports/FBgn0085486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34457, CG5197, SP118" - CG34457 11-Aug-17 DroID_v2017_08 Drer\cfap161 - - Xtro\cfap161 Mmus\Cfap161 Hsap\CFAP161 FBgn0259839 Su(Ste):CR42408 Su(Ste):CR42408 http://flybase.org/reports/FBgn0259839 non_protein_coding_gene - - - "Su(Ste):CR42408, CR42408" - CR42408 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033354 FANCI Fanconi anemia complementation group I http://flybase.org/reports/FBgn0033354 protein_coding_gene DNA polymerase binding ; GO:0070182 | inferred from biological aspect of ancestor with PANTHER:PTN000497925 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR026171 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs - "CG13745, FANCI, fanci" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR029314:FANCI solenoid 4 domain, IPR029315:FANCI solenoid 2 domain, IPR029313:FANCI solenoid 3 domain, IPR029308:FANCI solenoid 1 domain, IPR029312:FANCI helical domain 2, IPR026171:Fanconi anemia group I protein" CG13745 11-Aug-17 DroID_v2017_08 Drer\fanci - Cele\fnci-1 Xtro\polg Mmus\Fanci Hsap\FANCI viable FBgn0034803 CG9849 - http://flybase.org/reports/FBgn0034803 protein_coding_gene - muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:Q9BSG0 CG9849 IPR003137:PA domain CG9849 11-Aug-17 DroID_v2017_08 - - "Cele\ZC506.1, Cele\T07F12.2" Xtro\pradc1 Mmus\Pradc1 Hsap\PRADC1 viable embryonic/larval salivary gland FBgn0051752 CG31752 - http://flybase.org/reports/FBgn0051752 protein_coding_gene - - - "CG10599, CG31752" - CG31752 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC22599 K -0.315661475 0.552585453 0.027950964 -0.70852202 2.693544161 -0.079404907 FBgn0023496 Lip1 Lipase 1 http://flybase.org/reports/FBgn0023496 - protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 digestion ; GO:0007586 | inferred from expression pattern extracellular region ; GO:0005576 | non-traceable author statement "CG7279, lip1, Dmlip1, Lip1, dLip1, Lip, LIP1Dm, dilp1" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG7279 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH2, Scer\YEH1, Scer\TGL1" "Cele\lipl-5, Cele\lipl-6, Cele\lipl-1, Cele\lipl-2, Cele\lipl-3, Cele\lipl-7, Cele\lipl-4, Cele\lipl-8" Xtro\lipa "Mmus\Lipo4, Mmus\Lipa, Mmus\Lipf, Mmus\Lipo2, Mmus\Lipm, Mmus\Lipk, Mmus\Lipn, Mmus\Lipo3, Mmus\Lipo1" "Hsap\LIPN, Hsap\LIPJ, Hsap\LIPK, Hsap\LIPF, Hsap\LIPA, Hsap\LIPM" " adult stage | female , larval stage && pupal stage , adult stage | male , embryonic stage | late , embryonic stage | stage >=14 " " embryonic/larval pharynx

, embryonic/larval proventriculus

" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0262485 CG43075 - http://flybase.org/reports/FBgn0262485 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43075 - CG43075 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043967 U5E3sis U5E3sis http://flybase.org/reports/FBgn0043967 gene - - - U5E3sis - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083976 CG34140 - http://flybase.org/reports/FBgn0083976 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001406, InterPro:IPR020094, InterPro:IPR020095, InterPro:IPR020097, InterPro:IPR020103 pseudouridine synthase activity ; GO:0009982 | inferred from biological aspect of ancestor with PANTHER:PTN000124732" tRNA pseudouridine synthesis ; GO:0031119 | inferred from biological aspect of ancestor with PANTHER:PTN000124732 cellular_component ; GO:0005575 | no biological data available "CG7042, CG34140" "IPR020097:Pseudouridine synthase I, TruA, alpha/beta domain, IPR020103:Pseudouridine synthase, catalytic domain, IPR020095:Pseudouridine synthase I, TruA, C-terminal, IPR001406:Pseudouridine synthase I, TruA" CG34140 11-Aug-17 DroID_v2017_08 "Drer\pusl1, Drer\pus3" Scer\DEG1 "Cele\tag-124, Cele\Y73B6BL.29" Xtro\pusl1 "Mmus\Pus3, Mmus\Pusl1" "Hsap\PUSL1, Hsap\PUS3" "viable,fertile" FBgn0034363 CG5327 - http://flybase.org/reports/FBgn0034363 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs33e07, CG5327" "IPR008560:Protein of unknown function DUF842, eukaryotic" CG5327 11-Aug-17 DroID_v2017_08 Drer\fam136a - Cele\ZK637.2 Xtro\fam136a Mmus\Fam136a Hsap\FAM136A viable DRSC06930 K 0.175423074 0.010592763 0.998783334 0.601073732 3.331109329 0.389815284 FBgn0263588 CR43613 - http://flybase.org/reports/FBgn0263588 non_protein_coding_gene - - - "CR43613, lincRNA.892" - CR43613 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019812 fs(2)R female sterile (2) Ruplekha http://flybase.org/reports/FBgn0019812 - gene - - - fs(2)R - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,viable,female,poor" FBgn0037236 Skp2 S-phase kinase-associated protein 2 http://flybase.org/reports/FBgn0037236 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model regulation of protein stability ; GO:0031647 | inferred from mutant phenotype positive regulation of cell cycle ; GO:0045787 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype endomitotic cell cycle ; GO:0007113 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay "CG9772, 153298_at, Skp2, SKP2, FBXL1, dSkp2, F-box" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR006553:Leucine-rich repeat, cysteine-containing subtype" CG9772 11-Aug-17 DroID_v2017_08 Drer\skp2 Scer\RAD7 "Cele\T28B4.1, Cele\skpt-1" Xtro\skp2 Mmus\Skp2 Hsap\SKP2 "endomitotic cell cycle defective,mitotic cell cycle defective,increased cell death,lethal - all die before end of P-stage,some die during P-stage,viable,visible,decreased cell number,somatic clone" "embryonic/larval salivary gland,embryonic/larval brain,eye disc,wing disc,trichogen cell,wing hair,eye,somatic clone,wing margin,scutellum,mesothoracic tergum,chaeta" FBgn0266788 CR45253 - http://flybase.org/reports/FBgn0266788 non_protein_coding_gene - - - "CR45253, lincRNA.540" - CR45253 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037183 CG14451 - http://flybase.org/reports/FBgn0037183 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG14451 IPR013087:Zinc finger C2H2-type CG14451 11-Aug-17 DroID_v2017_08 "Drer\znf366, Drer\atmin" - "Cele\pag-3, Cele\zfp-2" Xtro\atmin "Mmus\Atmin, Mmus\Zfp366" Hsap\ZNF366 viable DRSC11708 I 0.507167396 -2.021058542 -0.557611659 0.372803626 -0.23982946 0.415282259 FBgn0266703 CR45193 - http://flybase.org/reports/FBgn0266703 non_protein_coding_gene - - - "CR45193, lincRNA.793" - CR45193 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264635 cincher cincher http://flybase.org/reports/FBgn0264635 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - cincher - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval dorsal trunk,embryonic/larval tracheal system,eye,somatic clone" FBgn0040053 CG17674 - http://flybase.org/reports/FBgn0040053 protein_coding_gene - - - CG17674 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015963 l(2)46DEa lethal (2) 46DEa http://flybase.org/reports/FBgn0015963 - gene - - - "group 5, l(2)46DEa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038453 Arl6IP1 ADP-ribosylation factor-like 6 interacting protein 1 http://flybase.org/reports/FBgn0038453 protein_coding_gene - endoplasmic reticulum tubular network membrane organization ; GO:1990809 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000468827 "CG10326, Arl6IP1" - CG10326 11-Aug-17 DroID_v2017_08 "Drer\arl6ip1, Drer\fam134a" - - Xtro\arl6ip1 "Mmus\Arl6ip1, Mmus\Fam134a" "Hsap\FAM134A, Hsap\ARL6IP1" "viable,fertile" DRSC14231 K 0.423422477 -1.159857152 0.550802758 0.499688451 2.509930766 0.834729044 FBgn0004738 l(3)85De lethal (3) 85De http://flybase.org/reports/FBgn0004738 - gene - - - l(3)85De - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039984 CG17473 - http://flybase.org/reports/FBgn0039984 protein_coding_gene - - - CG17473 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022994 ophthalmosa ophthalmosa http://flybase.org/reports/FBgn0022994 - gene - - - "ophthalmosa, opt" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260615 2L3064 - http://flybase.org/reports/FBgn0260615 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3064 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "dorsal air sac primordium,somatic clone" FBgn0265967 CR44754 - http://flybase.org/reports/FBgn0265967 non_protein_coding_gene - - - CR44754 - CR44754 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250841 CG17242 - http://flybase.org/reports/FBgn0250841 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular space ; GO:0005615 | inferred from direct assay "CG17242, SPH187, anon-SAGE:Wang-110" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG17242 11-Aug-17 DroID_v2017_08 Drer\si:ch211-165b19.9 - Cele\try-1 - "Mmus\Egfbp2, Mmus\Tmprss11a, Mmus\Tmprss11g, Mmus\Klk1b3, Mmus\Tmprss11f, Mmus\Prss53, Mmus\Klk1b8, Mmus\Klk1b9, Mmus\Prss50, Mmus\Klk1b5" "Hsap\CFD, Hsap\PRSS50, Hsap\TMPRSS11F, Hsap\TMPRSS11A, Hsap\PRSS36" FBgn0002057 l(2)40Fa lethal (2) 40Fa http://flybase.org/reports/FBgn0002057 - gene - - - "40Fa, l(2Lh)Fa, 40-18, GroupIX, l(2)EMS56-8, l(2)40Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,dominant,lethal" eye FBgn0002233 l(3)68Bf lethal (3) 68Bf http://flybase.org/reports/FBgn0002233 - gene - - - "l(3)B76, l(3)K, l(3)68Bf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal,polyphasic" "leg,wing" FBgn0264294 Cyt-b5 Cytochrome b5 http://flybase.org/reports/FBgn0264294 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Cyt-b5, CG2140, CYTB5, l(2)01857, 1857, BcDNA:RE66521, BcDNA:GH02503, CYT-B5, dpld, l(2)k00107" "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR018506:Cytochrome b5, heme-binding site" CG2140 11-Aug-17 DroID_v2017_08 "Drer\cyb5b, Drer\cyb5a" "Scer\CYB5, Scer\OLE1, Scer\CYB2, Scer\SCS7" "Cele\cytb-5.2, Cele\C25A1.5, Cele\cytb-5.1, Cele\D2023.1" "Xtro\cyb5b, Xtro\cyb5a" "Mmus\Cyb5d1, Mmus\Cyb5a, Mmus\Cyb5b, Mmus\Fa2h" "Hsap\FA2H, Hsap\CYB5B, Hsap\CYB5A" FBgn0082998 snoRNA:Psi28S-1192d snoRNA:Psi28S-1192d http://flybase.org/reports/FBgn0082998 snoRNA_gene - - - "snoRNA:Psi28S-1192d, Psi28S-1192d, psi28S-1192d, CR34594, chrX:16977850..16978043" - CR34594 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040477 cid centromere identifier http://flybase.org/reports/FBgn0040477 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000164, InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 microtubule motor activity ; GO:0003777 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with cal1" mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from genetic interaction with BubR1 kinetochore assembly ; GO:0051382 | inferred from mutant phenotype kinetochore organization ; GO:0051383 | inferred from direct assay mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype "chromosome, centromeric region ; GO:0000775 | inferred from direct assay condensed nuclear chromosome inner kinetochore ; GO:0000941 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay nuclear nucleosome ; GO:0000788 | inferred from physical interaction with His2A, His2B, His4 CENP-A containing nucleosome ; GO:0043505 | inferred from direct assay kinetochore ; GO:0000776 |" "CID, Cid, cid, CENP-A, CID/CENP-A, cenH3, cenpA, CENP-A/CID, CENP-A/Cid, CG13329, BcDNA:RE21270, CenpA/CID, CenH3, CenH3[Cid], Cenp-A, Cid[Mel], CenpA, CENPA, CENH3, CenH3[CID]" "IPR000164:Histone H3/CENP-A, IPR007125:Histone H2A/H2B/H3, IPR009072:Histone-fold" CG13329 11-Aug-17 DroID_v2017_08 "Drer\hist2h3c, Drer\zgc:113984, Drer\h3f3b.1, Drer\LOC108190746, Drer\zgc:113983, Drer\h3f3a, Drer\LOC108190747, Drer\zgc:173552, Drer\h3f3c, Drer\h3f3d, Drer\cenpa" "Scer\HHT1, Scer\CSE4, Scer\HHT2" "Cele\ZC155.2, Cele\his-71, Cele\his-73, Cele\hcp-3, Cele\his-69, Cele\cpar-1, Cele\F20D6.9" "Xtro\h3f3b, Xtro\cenpa, Xtro\hist2h3d" "Mmus\H3f3b, Mmus\Hist1h3i, Mmus\H3f3a, Mmus\Hist1h3d, Mmus\Hist1h3f, Mmus\Hist1h3c, Mmus\Hist2h3c1, Mmus\Hist2h3b, Mmus\Hist1h3g, Mmus\Cenpa, Mmus\Hist1h3b, Mmus\Hist1h3h, Mmus\Hist1h3e, Mmus\Hist1h3a, Mmus\Hist2h3c2" "Hsap\HIST1H3B, Hsap\HIST2H3C, Hsap\HIST1H3E, Hsap\CENPA, Hsap\HIST1H3I, Hsap\HIST3H3, Hsap\HIST1H3F, Hsap\H3F3B, Hsap\HIST1H3G, Hsap\HIST1H3J, Hsap\H3F3C, Hsap\HIST2H3D, Hsap\HIST1H3A, Hsap\HIST1H3C, Hsap\H3F3A, Hsap\HIST2H3A, Hsap\HIST1H3H, Hsap\HIST1H3D" " egg stage | fertilized egg , adult stage , embryonic stage " " male pronucleus

, spermatid

, female pronucleus

" "mitotic cell cycle defective,visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,cell cycle defective" "condensed nuclear chromosome,metaphase,nucleus,spindle,mitotic cell cycle,mitotic anaphase,anaphase & condensed nuclear chromosome,eye,ommatidium,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,chromosome,anaphase,telophase,metaphase plate" FBgn0060839 l(3)S049514 lethal (3) S049514 http://flybase.org/reports/FBgn0060839 gene - - - "0495/14, l(3)S049514" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0015850 anon-10Cc anon-10Cc http://flybase.org/reports/FBgn0015850 - gene - - - anon-10Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263943 BG00297 - http://flybase.org/reports/FBgn0263943 gene - - - BG00297 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0065234 l(2)SH2167 lethal (2) SH2167 http://flybase.org/reports/FBgn0065234 gene - - - "l(2)SH2167, l(2)SH2 2167" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041624 Or65b Odorant receptor 65b http://flybase.org/reports/FBgn0041624 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "CG32402, 65b, LU27.1, DOR63, Or65b" "IPR004117:Olfactory receptor, insect" CG32402 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040347 mus81 mus81 http://flybase.org/reports/FBgn0040347 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006166, InterPro:IPR020819 3'-flap endonuclease activity ; GO:0048257 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 crossover junction endodeoxyribonuclease activity ; GO:0008821 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000335543" double-strand break repair via break-induced replication ; GO:0000727 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 resolution of meiotic recombination intermediates ; GO:0000712 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 intra-S DNA damage checkpoint ; GO:0031573 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with mei-9 replication fork processing ; GO:0031297 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 DNA repair ; GO:0006281 | inferred from genetic interaction with Blm Holliday junction resolvase complex ; GO:0048476 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 "EG:BACR7A4.16, CG3026, mus81, Mus81" "IPR006166:ERCC4 domain, IPR010996:DNA polymerase beta-like, N-terminal domain, IPR011335:Restriction endonuclease type II-like" CG3026 11-Aug-17 DroID_v2017_08 Drer\mus81 Scer\MUS81 "Cele\mus-81, Cele\eme-1" Xtro\mus81 Mmus\Mus81 Hsap\MUS81 "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,chemical sensitive" FBgn0263981 CR43730 - http://flybase.org/reports/FBgn0263981 non_protein_coding_gene - - - CR43730 - CR43730 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016927 smi26D smell impaired 26D http://flybase.org/reports/FBgn0016927 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi26D - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0011667 Mst40 Male-specific RNA 40 http://flybase.org/reports/FBgn0011667 "FBgn0045090, FBgn0045255" gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "ORF1, bs35e07.y1, bs18c05.y1, NEST:bs35e07, NEST:bs18c05, Mst40, mst40" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052554 CG32554 - http://flybase.org/reports/FBgn0052554 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7871, CG32554" - CG32554 11-Aug-17 DroID_v2017_08 "Drer\cp, Drer\hephl1b" "Scer\FET3, Scer\FET5, Scer\GMC1" - Xtro\hephl1 "Mmus\Hephl1, Mmus\Cp, Mmus\Heph" "Hsap\HEPH, Hsap\CP, Hsap\HEPHL1" FBgn0001004 Fs(2)Ugr Female sterile (2) Ugra http://flybase.org/reports/FBgn0001004 - gene - eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype - "Fs(2)Ugra, Ugra, fs(2)Ugra, Fs(2)Sz12, Fs(2)Ugr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile soma-dependent,dominant,female sterile" "nurse cell,egg,egg chamber,vitelline membrane,inner chorionic layer,endochorion,oocyte & cytoplasm" FBgn0060389 l(3)S133807 lethal (3) S133807 http://flybase.org/reports/FBgn0060389 gene - - - "1338/07, l(3)S133807" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265897 CR44686 - http://flybase.org/reports/FBgn0265897 non_protein_coding_gene - - - CR44686 - CR44686 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052459 CG32459 - http://flybase.org/reports/FBgn0052459 protein_coding_gene - - - "CG8220, anon-WO0140519.31, CG32459" - CG32459 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0024709 anon-76Ca anon-76Ca http://flybase.org/reports/FBgn0024709 - gene - - - anon-76Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005218 l(3)ET10 lethal Elaine Tasaka 10 http://flybase.org/reports/FBgn0005218 - gene - - - l(3)ET10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,visible" tergite FBgn0046646 anon-38D.20 anon-38D.20 http://flybase.org/reports/FBgn0046646 gene - - - "38D.20, anon-38D.20" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053355 5SrRNA:CR33355 5SrRNA:CR33355 http://flybase.org/reports/FBgn0053355 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33355, 5SrRNA:CR33355" - CR33355 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259678 sqa spaghetti-squash activator http://flybase.org/reports/FBgn0259678 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 myosin light chain kinase activity ; GO:0004687 | inferred from biological aspect of ancestor with PANTHER:PTN002389378 protein kinase activity ; GO:0004672 | inferred from genetic interaction with Tsc1 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype" peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 autophagy ; GO:0006914 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from genetic interaction with Tsc1 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 positive regulation of TOR signaling ; GO:0032008 | inferred from genetic interaction with Tsc1 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 "CG1776, CG30004, sqa, CG42347, FBgn0259678" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG42347 11-Aug-17 DroID_v2017_08 "Drer\zgc:153952, Drer\si:dkey-240h12.4, Drer\phkg2, Drer\capsla, Drer\dscama, Drer\camk4, Drer\camk1a, Drer\uhmk1, Drer\camk1da, Drer\camk1gb, Drer\mylk4b, Drer\ttnb, Drer\pnck, Drer\si:ch211-27e6.1, Drer\mylk2, Drer\triob, Drer\camkva, Drer\pskh1, Drer\camk1b, Drer\stk17a, Drer\mylka, Drer\stk17b, Drer\stk33, Drer\si:ch73-60h1.1, Drer\camkvb, Drer\camk1ga, Drer\mylk3, Drer\phkg1a, Drer\mylkb, Drer\camkvl, Drer\trioa, Drer\dapk3, Drer\mylk4a, Drer\camk1db, Drer\capslb, Drer\dapk2a, Drer\dapk2b, Drer\dapk1, Drer\spegb" "Scer\RCK2, Scer\CMK2, Scer\KIC1, Scer\MEK1, Scer\PRR1, Scer\DUN1, Scer\CMK1, Scer\TDA1, Scer\RCK1, Scer\IKS1" "Cele\Y50D7A.3, Cele\ZC373.4, Cele\par-1, Cele\ZK524.4, Cele\unc-89" "Xtro\dscaml1, Xtro\dclk2, Xtro\capsl, Xtro\mylk, Xtro\dapk2, Xtro\stk17a, Xtro\dapk3, Xtro\pskh1, Xtro\kalrn, Xtro\mylk4, Xtro\dapk1, Xtro\pnck, Xtro\caps, Xtro\dscam, Xtro\phkg1, Xtro\phkg2, Xtro\camkv, Xtro\stk33, Xtro\mylk3, Xtro\trio, Xtro\camk1, Xtro\camk1d, Xtro\camk1g, Xtro\pskh2, Xtro\camk4" "Mmus\Dscam, Mmus\Capsl, Mmus\Phkg1, Mmus\Uhmk1, Mmus\Dapk2, Mmus\Mylk, Mmus\Pnck, Mmus\Caps2, Mmus\Dapk3, Mmus\Pskh1, Mmus\Camk1g, Mmus\Speg, Mmus\Mylk3, Mmus\Phkg2, Mmus\Camk1, Mmus\Dclk1, Mmus\Dapk1, Mmus\Stk17b, Mmus\Dscaml1, Mmus\Camkv, Mmus\Camk4, Mmus\Trio, Mmus\Camk1d, Mmus\Dclk2, Mmus\Snrk, Mmus\Stk33, Mmus\Mylk2, Mmus\Obscn, Mmus\Mylk4" "Hsap\MYLK4, Hsap\CAMK1G, Hsap\PHKG1, Hsap\CAPSL, Hsap\MYLK, Hsap\STK17A, Hsap\PHKG2, Hsap\CAMK1, Hsap\OBSCN, Hsap\CAMK1D, Hsap\CAMKV, Hsap\PSKH2, Hsap\DSCAML1, Hsap\UHMK1, Hsap\DAPK1, Hsap\CAMK4, Hsap\TRIO, Hsap\MYLK3, Hsap\MYLK2, Hsap\CAPS2, Hsap\DAPK3, Hsap\DAPK2, Hsap\ABL1, Hsap\SPEG, Hsap\PNCK, Hsap\DCLK1, Hsap\STK17B, Hsap\PSKH1, Hsap\STK33, Hsap\DSCAM, Hsap\CAPS" FBgn0019954 Nrt::wg Nrt::wg http://flybase.org/reports/FBgn0019954 - engineered_fusion_gene - - - "N-Wg, Nrt::wg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing & macrochaetaC-765,macrochaeta,ectopic,denticle belt" FBgn0028038 l(3)S100209 lethal (3) S100209 http://flybase.org/reports/FBgn0028038 gene - - - "1002/09, l(3)S100209" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0011743 Arp53D Actin-related protein 53D http://flybase.org/reports/FBgn0011743 - protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity actin filament ; GO:0005884 | inferred from sequence or structural similarity "arp53D, CG5409, ARP53D, arp5, Actr53D, Arp53D, Arp_G, ArpG" "IPR020902:Actin/actin-like conserved site, IPR004000:Actin family" CG5409 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-241j12.3, Drer\actr1, Drer\actb2, Drer\zgc:86725, Drer\actc1a, Drer\si:ch73-187m15.4, Drer\acta2, Drer\actb1, Drer\acta1a, Drer\zgc:86709, Drer\acta1b, Drer\ankrd52b, Drer\actc1b, Drer\actr10" "Scer\ARP1, Scer\ARP8, Scer\ARP9, Scer\ACT1" "Cele\act-3, Cele\act-2, Cele\act-1, Cele\act-4" "Xtro\acta1, Xtro\actr1a, Xtro\acta2, Xtro\actc1, Xtro\actr10, Xtro\ankrd52, Xtro\act3, Xtro\actb, Xtro\actg1" "Mmus\Actc1, Mmus\Actb, Mmus\Actrt1, Mmus\Actr1a, Mmus\Actr1b, Mmus\Actrt3, Mmus\Actr10, Mmus\Actg2, Mmus\Acta1, Mmus\Actr8, Mmus\Actbl2, Mmus\Actg1, Mmus\Actl9, Mmus\Actl11, Mmus\Actl7b, Mmus\Actl7a, Mmus\Actrt2, Mmus\Actl10, Mmus\Acta2" "Hsap\POTEJ, Hsap\ACTB, Hsap\POTEE, Hsap\ACTRT1, Hsap\ACTR8, Hsap\ACTRT3, Hsap\ACTL7A, Hsap\ACTL10, Hsap\ACTR1A, Hsap\ACTC1, Hsap\ACTR1B, Hsap\ACTG1, Hsap\ACTG2, Hsap\ACTRT2, Hsap\ACTR10, Hsap\ACTBL2, Hsap\ACTL7B, Hsap\ACTL9, Hsap\ACTA2, Hsap\ACTA1, Hsap\ACTL8, Hsap\POTEI, Hsap\POTEF" " pupal stage , spermatogenesis && adult stage , adult stage | male " testis

viable FBgn0067879 Mod(Prat:bw)2-4 Mod(Prat:bw)2-4 http://flybase.org/reports/FBgn0067879 gene - - - "Mod-2-4, Mod(Prat:bw)2-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0042199 CG13713 - http://flybase.org/reports/FBgn0042199 protein_coding_gene - regulation of localization ; GO:0032879 | inferred from sequence or structural similarity with halo - "HL2, CG18465, CG13713" IPR007970:Protein of unknown function DUF733 CG13713 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038804 CG10877 - http://flybase.org/reports/FBgn0038804 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR003673 - - CG10877 "IPR003673:CoA-transferase family III, IPR023606:CoA-transferase family III domain" CG10877 11-Aug-17 DroID_v2017_08 "Drer\amacr, Drer\sugct" - Cele\C24A3.4 "Xtro\amacr, Xtro\sugct" "Mmus\Amacr, Mmus\Sugct" "Hsap\SUGCT, Hsap\AMACR" viable FBgn0027592 MED15 Mediator complex subunit 15 http://flybase.org/reports/FBgn0027592 - protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with UniProtKB:Q9W0P8 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR019087 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with UniProtKB:Q9W0P8 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from sequence or structural similarity with UniProtKB:Q9W0P8 "Arc105, Med9/ARC105, dARC105, CG4184, BcDNA:GH03922, MED15, Med15, med15" "IPR019087:Mediator of RNA polymerase II transcription subunit 15, IPR003101:Coactivator CBP, KIX domain" CG4184 11-Aug-17 DroID_v2017_08 Drer\med15 - - Xtro\LOC100493634 Mmus\Med15 Hsap\MED15 "visible,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage" "wing margin,wing,wing vein L2,distal,wing sensillum,ectopic,wing disc" DRSC00267 IK 0.93621912 1.842426673 0.26150271 1.259472352 0.93466722 2.099781538 FBgn0031164 CG1724 - http://flybase.org/reports/FBgn0031164 protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000050380 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O60830 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O60830 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:O60830 "BcDNA:AT13347, CG1724" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG1724 11-Aug-17 DroID_v2017_08 "Drer\timm17a, Drer\timm17b" Scer\TIM17 "Cele\E04A4.5, Cele\D2096.1, Cele\C47G2.3" Xtro\timm17a "Mmus\Timm17b, Mmus\Timm17a" "Hsap\TIMM17B, Hsap\TIMM17A" viable FBgn0002135 l(2)K224 lethal (2) K224 http://flybase.org/reports/FBgn0002135 - gene - - - l(2)K224 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032014 CG7840 - http://flybase.org/reports/FBgn0032014 protein_coding_gene "oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from electronic annotation with InterPro:IPR001104" dolichol metabolic process ; GO:0019348 | inferred from sequence or structural similarity with UniProtKB:Q9H8P0 polyprenol catabolic process ; GO:0016095 | inferred from sequence or structural similarity with UniProtKB:Q9H8P0 dolichol-linked oligosaccharide biosynthetic process ; GO:0006488 | inferred from sequence or structural similarity with UniProtKB:Q9H8P0 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001104 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001104 "cg7840, CG7840" "IPR001104:3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal" CG7840 11-Aug-17 DroID_v2017_08 Drer\srd5a3 Scer\DFG10 Cele\B0024.13 Xtro\srd5a3 Mmus\Srd5a3 Hsap\SRD5A3 viable FBgn0024251 bbx bobby sox http://flybase.org/reports/FBgn0024251 "FBgn0014083, FBgn0052527, FBtr0077200, FBpp0076899, FBtr0077201, FBpp0076900, FBtr0077202, FBpp0076901" protein_coding_gene - - - "tu2, CG32527, anon-19Fb, CG1414, bbx" IPR009071:High mobility group box domain CG1414 11-Aug-17 DroID_v2017_08 "Drer\cica, Drer\cicb, Drer\sox21b" - - - "Mmus\Cic, Mmus\Bbx" "Hsap\BBX, Hsap\SOX14, Hsap\SOX21" "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0265165 CR44234 - http://flybase.org/reports/FBgn0265165 non_protein_coding_gene - - - "CR44234, lincRNA.762" - CR44234 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262412 mir-1008 mir-1008 stem loop http://flybase.org/reports/FBgn0262412 miRNA_gene - - - "mir-1008, dme-mir-1008, CR42957, miR-1008, dme-miR-1008" - CR42957 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000020 abt abnormal tergites http://flybase.org/reports/FBgn0000020 - gene - - - abt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male,male sterile,partially,recessive,male semi-sterile,body color defective" "adult abdomen & microchaeta,eye,ommatidium,wing,wing vein,tergite,adult abdomen" FBgn0043554 Su(ro[DOM])519 Su(ro[DOM])519 http://flybase.org/reports/FBgn0043554 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])519 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,dominant" eye FBgn0044049 Ilp4 Insulin-like peptide 4 http://flybase.org/reports/FBgn0044049 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 larval feeding behavior ; GO:0030536 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "mes3, CG6736, dilp4, dilp, Mes3, anon-EST:CLB3, dilp-4, DILP, Dilp, Dilp 4, Dirlp, DILP4, A, BcDNA:RE27042, Ilp4, Ilp, ilp4, Ilp-4, Dilp4, DILP-4, dILP4" "IPR016179:Insulin-like, IPR022352:Insulin family, IPR022353:Insulin, conserved site" CG6736 11-Aug-17 DroID_v2017_08 "Drer\insl3, Drer\insl5b" - - - Mmus\Insl3 Hsap\INSL3 " embryonic stage | stage >5 , larval stage | third instar , embryonic stage | cellular blastoderm , embryonic stage | stage 12-16 , embryonic stage | stage 2-12 , embryonic stage | stage 5 " " mesoderm

, embryonic/larval midgut

, mesoderm anlage

, anterior midgut proper primordium

" "feeding behavior defective,large body,viable" embryonic/larval neuroblast FBgn0035763 CG8602 - http://flybase.org/reports/FBgn0035763 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "anon-WO0118547.382, anon-WO0118547.349, CG8602" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8602 11-Aug-17 DroID_v2017_08 "Drer\mfsd1, Drer\im:7160594" - - "Xtro\mfsd1, Xtro\LOC100487982" Mmus\Mfsd1 Hsap\MFSD1 FBgn0016953 tilJ touch insensitive larva J http://flybase.org/reports/FBgn0016953 - gene - - - "line 366, tilJ" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective,uncoordinated" FBgn0044455 EP3561 EP3561 http://flybase.org/reports/FBgn0044455 gene - - - EP3561 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0037779 CG12811 - http://flybase.org/reports/FBgn0037779 protein_coding_gene - - - CG12811 IPR031993:Domain of unknown function DUF4789 CG12811 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033190 CG2137 - http://flybase.org/reports/FBgn0033190 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from sequence or structural similarity with UniProtKB:P43304 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000447, InterPro:IPR006076, InterPro:IPR023753 glycerol-3-phosphate metabolic process ; GO:0006072 | inferred from electronic annotation with InterPro:IPR000447 glycerol metabolic process ; GO:0006071 | inferred from sequence or structural similarity with UniProtKB:P43304" glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR000447 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P43304 "146747_at, CG2137, alpha-GPO, Gpo, GPO, gpo-2, GPO-2" "IPR000447:FAD-dependent glycerol-3-phosphate dehydrogenase, IPR002048:EF-hand domain, IPR006076:FAD dependent oxidoreductase, IPR011992:EF-hand domain pair, IPR031656:Alpha-glycerophosphate oxidase, C-terminal, IPR023753:FAD/NAD(P)-binding domain" CG2137 11-Aug-17 DroID_v2017_08 Drer\gpd2 Scer\GUT2 "Cele\Y50E8A.6, Cele\T25G3.4" Xtro\gpd2 Mmus\Gpd2 Hsap\GPD2 viable FBgn0002558 lop lobula plateless http://flybase.org/reports/FBgn0002558 - gene - - - "N684, lop" - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective lobula plate FBgn0011634 l(2)T57h7 lethal (2) T57h7 http://flybase.org/reports/FBgn0011634 FBgn0005177 gene - - - l(2)T57h7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259876 Cap-G Chromosome associated protein G http://flybase.org/reports/FBgn0259876 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype sister chromatid segregation ; GO:0000819 | inferred from mutant phenotype synaptonemal complex disassembly ; GO:0070194 | inferred from mutant phenotype "chromatin ; GO:0000785 | inferred from direct assay nuclear heterochromatin ; GO:0005720 | colocalizes_with inferred from direct assay chromosome, centromeric region ; GO:0000775 | colocalizes_with inferred from direct assay condensin complex ; GO:0000796 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:24304 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000373921" "CAP-G, Cap-G, CapG, l(2)49Ff, CG17054, CG30057, CG13327, dcap-g, cap-G, dCAP-G, DCAP-G, CG34438, vr9, vr-9, l(2)vr9, DmCAP-G, dCap-G, cap-g" "IPR016024:Armadillo-type fold, IPR027165:Condensin complex subunit 3, IPR011989:Armadillo-like helical, IPR025977:Nuclear condensin complex subunit 3, C-terminal domain" CG34438 11-Aug-17 DroID_v2017_08 Drer\ncapg Scer\YCG1 - Xtro\ncapg Mmus\Ncapg Hsap\NCAPG DRSC06653 IE 3.254948018 0.570605478 1.724249188 0.641673269 -0.18038739 1.071479412 FBgn0266418 wake wide awake http://flybase.org/reports/FBgn0266418 protein_coding_gene GABA receptor binding ; GO:0050811 | inferred from physical interaction with Rdl "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000159 regulation of establishment of bipolar cell polarity ; GO:0061172 | inferred from mutant phenotype asymmetric stem cell division ; GO:0098722 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype" spindle ; GO:0005819 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "ban, wake, CG42686, CG6954, CG45058, CG17622, CG17623" "IPR020683:Ankyrin repeat-containing domain, IPR002110:Ankyrin repeat, IPR013783:Immunoglobulin-like fold, IPR003961:Fibronectin type III, IPR000159:Ras-associating (RA) domain" CG45058 11-Aug-17 DroID_v2017_08 Drer\si:ch211-277e21.2 - Cele\R07E4.1 "Xtro\ankfn1, Xtro\LOC100490407" Mmus\Ankfn1 Hsap\ANKFN1 FBgn0266100 CG44837 - http://flybase.org/reports/FBgn0266100 protein_coding_gene dipeptidase activity ; GO:0016805 | inferred from biological aspect of ancestor with PANTHER:PTN000047764 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008257 - "CG44837, CG14126, CG34420, CG5917, CG14129" "IPR008257:Renal dipeptidase family, IPR032466:Metal-dependent hydrolase" CG44837 11-Aug-17 DroID_v2017_08 "Drer\dpep1, Drer\dpep2" - - "Xtro\dpep1, Xtro\dpep2" "Mmus\Dpep2, Mmus\Dpep1, Mmus\Dpep3" "Hsap\DPEP2, Hsap\DPEP1, Hsap\DPEP3" DRSC10133 I -0.636539603 -1.534662136 0.855732895 -1.464536939 0.727738114 -0.04722746 FBgn0037068 Cpr78Cb Cuticular protein 78Cb http://flybase.org/reports/FBgn0037068 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "anon-EST:ParkEST240, BcDNA:RE38359, Cpr78Cb, CG7663, DmelCpr78Cb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG7663 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0026357 Su(SuRaf1)10 Su(SuRaf1)10 http://flybase.org/reports/FBgn0026357 - gene - - - "Su[Su(Raf)1]10, Su(SuRaf1)10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021805 l(2)k16801 lethal (2) k16801 http://flybase.org/reports/FBgn0021805 - gene - - - l(2)k16801 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0250733 l(3)S006313 lethal (3) S006313 http://flybase.org/reports/FBgn0250733 gene - - - "l(3)S006313, l(3)s006313" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266459 CG45084 - http://flybase.org/reports/FBgn0266459 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45084, Dromel_CG4824_FBtr0080804_bicc_uORF" - CG45084 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023465 anon-56Cc anon-56Cc http://flybase.org/reports/FBgn0023465 - gene - - - anon-56Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage && oogenesis stage " ovary

, nurse cell

" FBgn0051493 CG31493 - http://flybase.org/reports/FBgn0051493 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 "CG2640, CG31493" IPR016181:Acyl-CoA N-acyltransferase CG31493 11-Aug-17 DroID_v2017_08 - - "Cele\anat-1, Cele\T10B5.4" - - - viable FBgn0085308 CG34279 - http://flybase.org/reports/FBgn0085308 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34279 IPR002350:Kazal domain CG34279 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086909 CG31751 - http://flybase.org/reports/FBgn0086909 protein_coding_gene - - - "ct, CG15164, CG15163, CG31751, anon-ct" "IPR002575:Aminoglycoside phosphotransferase, IPR011009:Protein kinase-like domain" CG31751 11-Aug-17 DroID_v2017_08 "Drer\hykk.2, Drer\hykk.1" - - Xtro\hykk Mmus\Hykk Hsap\HYKK embryonic stage -- adult stage FBgn0265755 CR44562 - http://flybase.org/reports/FBgn0265755 non_protein_coding_gene - - - CR44562 - CR44562 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026438 Eaat2 Excitatory amino acid transporter 2 http://flybase.org/reports/FBgn0026438 - protein_coding_gene glutamate:sodium symporter activity ; GO:0015501 | inferred from sequence or structural similarity taurine:sodium symporter activity ; GO:0005369 | inferred from direct assay L-aspartate transmembrane transporter activity ; GO:0015183 | inferred from direct assay taurine transport ; GO:0015734 | inferred from direct assay taurine transport ; GO:0015734 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001991 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "dEAAT2, EAAT, CG3159, Eaat2, dEaat2" "IPR018107:Sodium:dicarboxylate symporter, conserved site, IPR001991:Sodium:dicarboxylate symporter" CG3159 11-Aug-17 DroID_v2017_08 "Drer\slc1a9, Drer\slc1a7b, Drer\slc1a3b, Drer\slc1a2b, Drer\slc1a7a, Drer\slc1a8a, Drer\slc1a4, Drer\slc1a5, Drer\slc1a6, Drer\slc1a1, Drer\slc1a2a, Drer\slc1a8b, Drer\slc1a3a" - "Cele\glt-1, Cele\glt-7, Cele\glt-4, Cele\glt-6, Cele\glt-3, Cele\glt-5" "Xtro\slc1a3, Xtro\slc1a1, Xtro\slc1a7, Xtro\slc1a4, Xtro\LOC100496635, Xtro\slc1a5, Xtro\slc1a2, Xtro\slc1a6" "Mmus\Slc1a3, Mmus\Slc1a7, Mmus\Slc1a5, Mmus\Slc1a2, Mmus\Slc1a6, Mmus\Slc1a4, Mmus\Slc1a1" "Hsap\SLC1A1, Hsap\SLC1A5, Hsap\SLC1A6, Hsap\SLC1A7, Hsap\SLC1A4, Hsap\SLC1A3, Hsap\SLC1A2" " embryonic stage | stage 15-16 , embryonic stage | stage 17 , adult stage , embryonic stage | stage 16-17 , larval stage | third instar " " Bolwig's organ | presumptive

, interneuron

, midline glial cell

, ocellus

, sense organ & neuron | subset

, larval central nervous system

, adult head

, retina

, ventral nerve cord

,

anterior , glial cell

, CNS glial cell | subset

" "viable,chemosensitive behavior defective" FBgn0259222 CG42322 - http://flybase.org/reports/FBgn0259222 protein_coding_gene - - - "CG42322, CG15690, CG15689, CG15688, CG31203" IPR026505:Solute carrier family 35 member F3/F4 CG42322 11-Aug-17 DroID_v2017_08 "Drer\slc35f3b, Drer\slc35f3a, Drer\slc35f4" - Cele\Y73B6BL.31 "Xtro\slc35f4, Xtro\slc35f3" "Mmus\Slc35f4, Mmus\Slc35f3" "Hsap\SLC35F3, Hsap\SLC35F4" FBgn0031751 CG9016 - http://flybase.org/reports/FBgn0031751 protein_coding_gene - - - "bs24f02.y1, bs20d08.y1, bs36f07.y1, bs29f11.y1, bs29e04.y1, bs28b03.y1, bs27b06.y1, bs25d03.y1, bs22a02.y1, bs21a02.y1, bs19d06.y1, bs18b05.y1, bs16d01.y1, bs16c10.y1, bs14b11.y1, bs13h06.y1, bs10f09.y1, bs10d11.y1, bs09c06.y1, bs07e11.y1, bs05g03.y1, bs03c03.y1, NEST:bs24f02, NEST:bs20d08, BcDNA:AT19175, NEST:bs09a09, NEST:bs36a03, CG9016" - CG9016 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0003935 snRNA:U5:34A small nuclear RNA U5 at 34AB http://flybase.org/reports/FBgn0003935 "FBgn0003932, FBgn0051853" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-34A, snRNA[[3]], K2, dU5, snRNA:U5:34AB, snRNA:U5, snRNA4, snRNA3, U5snRNA34AB, CR31853, U5snRNA, snRNA:U5:34A, U5:34A, U5 snRNA, U5 snRNA 34A, 34B U5" - CR31853 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004686 mei-I1 meiotic I1 http://flybase.org/reports/FBgn0004686 - gene - - - mei-I1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive" "meiosis I,spermatocyte,spermatid" FBgn0016782 anon-8Db anon-8Db http://flybase.org/reports/FBgn0016782 - gene - - - anon-8Db - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010866 l(3)05430 lethal (3) 05430 http://flybase.org/reports/FBgn0010866 - gene molecular_function ; GO:0003674 | no biological data available embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(3)05430 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive,maternal effect,poor" "embryonic/first instar larval cuticle,maternal effect" FBgn0035816 CG13685 - http://flybase.org/reports/FBgn0035816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13685 - CG13685 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025773 l(3)89Ab lethal (3) 89Ab http://flybase.org/reports/FBgn0025773 - gene - - - l(3)89Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005574 l(3)85Ej lethal (3) 85Ej http://flybase.org/reports/FBgn0005574 - gene - - - l(3)85Ej - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022137 l(2)k06327 lethal (2) k06327 http://flybase.org/reports/FBgn0022137 - gene - - - l(2)k06327 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005398 pch parched http://flybase.org/reports/FBgn0005398 "FBgn0000050, FBgn0001333, FBgn0003043, FBgn0004645" gene - - - "l(1)1Aa, lEC1, EC1, EC2, l[EC1], l(1)[d], l(1)d, l(1)HF310, l(1)7e, dmd, addB, pch" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0001412 l(1)3Eb lethal (1) 3Eb http://flybase.org/reports/FBgn0001412 - gene - - - "GF332, l(1)3Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovary,germline clone,follicle cell" FBgn0266468 noix - http://flybase.org/reports/FBgn0266468 gene - - - noix - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cell polarity defective,germline clone" "egg chamber,germline clone,oocyte,centrosome | germline clone" FBgn0025753 l(3)93DFi lethal (3) 93DFi http://flybase.org/reports/FBgn0025753 - gene - - - l(3)93DFi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069131 mei(2)yh15 mei(2)yh15 http://flybase.org/reports/FBgn0069131 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(2)yh15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,female fertile" FBgn0267782 CR46113 - http://flybase.org/reports/FBgn0267782 non_protein_coding_gene - - - CR46113 - CR46113 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030876 CG6762 - http://flybase.org/reports/FBgn0030876 protein_coding_gene sulfiredoxin activity ; GO:0032542 | inferred from biological aspect of ancestor with PANTHER:PTN002328029 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR016692 cellular response to oxidative stress ; GO:0034599 | inferred from biological aspect of ancestor with PANTHER:PTN002328029 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN002328029 CG6762 "IPR016692:Sulfiredoxin, IPR003115:ParB/Sulfiredoxin" CG6762 11-Aug-17 DroID_v2017_08 Drer\srxn1 Scer\SRX1 - - Mmus\Srxn1 Hsap\SRXN1 viable FBgn0036938 CG14187 - http://flybase.org/reports/FBgn0036938 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern chorion ; GO:0042600 | inferred by curator from GO:0007304 CG14187 - CG14187 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052418 vito viriato http://flybase.org/reports/FBgn0052418 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype nucleolus organization ; GO:0007000 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay "CG10569, vito, CG32418" IPR019186:Nucleolar protein 12 CG32418 11-Aug-17 DroID_v2017_08 "Drer\pkmyt1, Drer\wee2, Drer\wee1, Drer\nol12" "Scer\RRP17, Scer\SWE1" - "Xtro\nol12, Xtro\pkmyt1" "Mmus\Wee2, Mmus\Wee1, Mmus\Pkmyt1, Mmus\Nol12" "Hsap\WEE2, Hsap\WEE1, Hsap\PKMYT1, Hsap\NOL12" "size defective,recessive,developmental rate defective,increased cell death,decreased cell number,somatic clone,decreased cell size,viable,visible" "eye,eye disc,somatic clone | third instar larval stage,embryonic/larval salivary gland,nucleolus | third instar larval stageptc-559.1,trichogen cell" FBgn0038332 CG6136 - http://flybase.org/reports/FBgn0038332 protein_coding_gene "copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR005627, InterPro:IPR023648" "copper ion homeostasis ; GO:0055070 | inferred from electronic annotation with InterPro:IPR005627, InterPro:IPR023648 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" - CG6136 "IPR005627:Copper homeostasis protein CutC, IPR023648:Copper homeostasis CutC domain" CG6136 11-Aug-17 DroID_v2017_08 Drer\cutc - Cele\cutc-1 Xtro\cutc Mmus\Cutc Hsap\CUTC viable FBgn0266895 CR45355 - http://flybase.org/reports/FBgn0266895 non_protein_coding_gene - - - CR45355 - CR45355 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061003 l(3)S026532 lethal (3) S026532 http://flybase.org/reports/FBgn0061003 gene - - - "0265/32, l(3)S026532" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0002087 l(2)52Ea lethal (2) 52Ea http://flybase.org/reports/FBgn0002087 - gene - - - "KL-32-1, l(2)52Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060997 l(3)S027114 lethal (3) S027114 http://flybase.org/reports/FBgn0060997 gene - - - "0271/14, l(3)S027114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0032846 CG10721 - http://flybase.org/reports/FBgn0032846 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 - "38B.14, CG10721" IPR023753:FAD/NAD(P)-binding domain CG10721 11-Aug-17 DroID_v2017_08 Drer\ryroxd1 - Cele\C26D10.3 Xtro\pyroxd1 Mmus\Pyroxd1 Hsap\PYROXD1 viable FBgn0033587 CG13218 - http://flybase.org/reports/FBgn0033587 protein_coding_gene - - - CG13218 - CG13218 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264295 CG43773 - http://flybase.org/reports/FBgn0264295 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43773, CG10039" - CG43773 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043050 anon-50Ea anon-50Ea http://flybase.org/reports/FBgn0043050 gene - - - "t2, T2, anon-50Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265964 CR44751 - http://flybase.org/reports/FBgn0265964 non_protein_coding_gene - - - CR44751 - CR44751 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260279 GSd496 - http://flybase.org/reports/FBgn0260279 gene - - - GSd496 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0001171 ha hair bristles http://flybase.org/reports/FBgn0001171 - gene - - - ha - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,female,reduced,male fertile,female sterile,recessive,visible" macrochaeta FBgn0005141 l(2)CA6 lethal (2) CA6 http://flybase.org/reports/FBgn0005141 - gene - - - "l(2)br6, l(1)br6, l(2)CA6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259979 CG17337 - http://flybase.org/reports/FBgn0259979 protein_coding_gene dipeptidase activity ; GO:0016805 | inferred from electronic annotation with InterPro:IPR017153 metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR001261 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001261 extracellular region ; GO:0005576 | inferred from direct assay "CG17337, Y, anon-41Fb, Dm52" "IPR001261:ArgE/DapE/ACY1/CPG2/YscS, conserved site, IPR002933:Peptidase M20, IPR011650:Peptidase M20, dimerisation domain, IPR017153:Cytosolic nonspecific dipeptidase/DUG1" CG17337 11-Aug-17 DroID_v2017_08 "Drer\cndp2, Drer\zgc:114181" "Scer\DUG1, Scer\DUG2" "Cele\pes-9, Cele\Y71H2AM.11" "Xtro\cndp2, Xtro\cndp1, Xtro\darmin" "Mmus\Cndp1, Mmus\Cndp2" "Hsap\CNDP1, Hsap\CNDP2" embryonic stage embryonic/larval digestive system

FBgn0026619 Taz Tafazzin http://flybase.org/reports/FBgn0026619 - protein_coding_gene "phosphatidylcholine:cardiolipin O-linoleoyltransferase activity ; GO:0032577 | inferred from direct assay transferase activity, transferring acyl groups ; GO:0016746 | inferred from direct assay" cardiolipin metabolic process ; GO:0032048 | inferred from direct assay cardiolipin acyl-chain remodeling ; GO:0035965 | inferred from biological aspect of ancestor with PANTHER:PTN000281558 cardiolipin biosynthetic process ; GO:0032049 | inferred from mutant phenotype mitochondrial membrane organization ; GO:0007006 | inferred from direct assay inner mitochondrial membrane organization ; GO:0007007 | inferred from biological aspect of ancestor with PANTHER:PTN000281558 phospholipid metabolic process ; GO:0006644 | inferred by curator from GO:0032577 sperm individualization ; GO:0007291 | inferred from mutant phenotype phospholipid metabolic process ; GO:0006644 | inferred from direct assay mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000281558 intrinsic component of membrane ; GO:0031224 | inferred from biological aspect of ancestor with PANTHER:PTN000281557 mitochondrion ; GO:0005739 | inferred from direct assay "CG8766, Taz, tafazzin, dTAZ, TAZ" "IPR000872:Tafazzin, IPR002123:Phospholipid/glycerol acyltransferase" CG8766 11-Aug-17 DroID_v2017_08 Drer\taz Scer\TAZ1 Cele\acl-3 Xtro\taz Mmus\Taz Hsap\TAZ "locomotor behavior defective,male sterile,recessive,viable,body color defective" "indirect flight muscle & mitochondrion,mitochondrial crista,mitochondrion,individualization stage spermatid,spermatid cyst,mesothoracic tergum" FBgn0030467 CG1764 - http://flybase.org/reports/FBgn0030467 protein_coding_gene - - - "CG1764, cg1764" IPR033199:Dimethylarginine dimethylaminohydrolase/arginine deiminase CG1764 11-Aug-17 DroID_v2017_08 "Drer\ddah1, Drer\ddah2" - "Cele\ZK1307.1, Cele\fbxa-11, Cele\T22B7.3" "Xtro\ddah2, Xtro\ddah1" "Mmus\Ddah2, Mmus\Ddah1" "Hsap\DDAH1, Hsap\DDAH2" "viable,fertile" FBgn0065350 l(2)SH1806 lethal (2) SH1806 http://flybase.org/reports/FBgn0065350 gene - - - "l(2)SH1806, l(2)SH2 1806" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027788 Hey Hairy/E(spl)-related with YRPW motif http://flybase.org/reports/FBgn0027788 FBgn0027789 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q9QUS4 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650 negative regulation of Notch signaling pathway ; GO:0045746 | inferred from sequence or structural similarity with UniProtKB:Q9QUS4 neuron fate determination ; GO:0048664 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9QUS4 "Hey, d-hey, CG11194, Hesr-1, dHey, hesr-1, hey, bHLHe44, HEY" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG11194 11-Aug-17 DroID_v2017_08 "Drer\her9, Drer\her8.2, Drer\heyl, Drer\her8a, Drer\hes6, Drer\helt, Drer\hes2.1, Drer\hey1, Drer\her5, Drer\hey2, Drer\her11, Drer\her1, Drer\bhlhe41, Drer\her6, Drer\bhlhe40, Drer\her13, Drer\hes2.2" Scer\PHO4 Cele\lin-22 "Xtro\hey1, Xtro\bhlhe41, Xtro\hes7.1, Xtro\hes2, Xtro\hes1, Xtro\hes6.1, Xtro\hey2, Xtro\hes4, Xtro\hes7.2, Xtro\bhlhe40" "Mmus\Heyl, Mmus\Bhlhe41, Mmus\Hey2, Mmus\Hes7, Mmus\Helt, Mmus\Bhlhe40, Mmus\Hey1, Mmus\Hes6, Mmus\Hes1, Mmus\Hes2" "Hsap\HEY1, Hsap\HELT, Hsap\HEYL, Hsap\HES6, Hsap\BHLHE41, Hsap\HEY2, Hsap\HES1, Hsap\HES2, Hsap\HES4, Hsap\BHLHE40" "lethal - all die before end of second instar larval stage,some die during embryonic stage,majority die during first instar larval stage,neuroanatomy defective" "RP2 motor neuron,RP2sib neuron,dMP2 neuron,vMP2 neuron" FBgn0265151 CR44220 - http://flybase.org/reports/FBgn0265151 non_protein_coding_gene - - - CR44220 - CR44220 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266322 CR44987 - http://flybase.org/reports/FBgn0266322 non_protein_coding_gene - - - CR44987 - CR44987 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011316 l(3)j1D5 lethal (3) j1D5 http://flybase.org/reports/FBgn0011316 - gene - - - l(3)j1D5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262999 CG43307 - http://flybase.org/reports/FBgn0262999 protein_coding_gene - - - "CG43307, lincRNA.52" IPR002350:Kazal domain CG43307 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039151 CG13607 - http://flybase.org/reports/FBgn0039151 protein_coding_gene - - - "CG13607, 150482_at" - CG13607 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060994 l(3)S027318b lethal (3) S027318b http://flybase.org/reports/FBgn0060994 gene - - - "0273/18, l(3)S027318b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0043010 Fsn F-box synaptic protein http://flybase.org/reports/FBgn0043010 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with hiw inferred from physical interaction with Rae1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NB71 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model cell cortex ; GO:0005938 | inferred from direct assay pole plasm ; GO:0045495 | inferred from direct assay SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "BEST:GH20696, DFsn, Wals, Fsn, CG4643, FBXO2, dFsn, fsn" "IPR001810:F-box domain, IPR001870:B30.2/SPRY domain, IPR003877:SPRY domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG4643 11-Aug-17 DroID_v2017_08 "Drer\fbxo45, Drer\spsb3b, Drer\spsb1, Drer\spsb4b, Drer\spsb4a" - "Cele\spsb-1, Cele\fsn-1, Cele\spsb-2" "Xtro\fbxo45, Xtro\spsb1" "Mmus\Spsb2, Mmus\Spsb4, Mmus\Spsb1, Mmus\Fbxo45" "Hsap\SPSB1, Hsap\SPSB2, Hsap\FBXO45, Hsap\SPSB4" "partially lethal - majority live,maternal effect,viable,male sterile,neuroanatomy defective,neurophysiology defective,body color defective" "type I bouton,supernumerary,embryonic/larval neuromuscular junction,pole cell,maternal effect,mesothoracic tergum" FBgn0019674 mor(1)5 mortality gene (1)5 http://flybase.org/reports/FBgn0019674 - gene - - - mor(1)5 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0023137 WppF White prepupal locus F http://flybase.org/reports/FBgn0023137 - gene - - - "8, 15, WppF" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029820 CG16721 - http://flybase.org/reports/FBgn0029820 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cAMP-mediated signaling ; GO:0019933 | inferred from sequence or structural similarity with SGD:S000002413 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002413 CG16721 IPR008862:T-complex 11 CG16721 11-Aug-17 DroID_v2017_08 "Drer\tcp11l1, Drer\tcp11l2" Scer\SOK1 Cele\M05D6.2 "Xtro\tcp11l1, Xtro\tcp11l2" "Mmus\Tcp11x2, Mmus\Tcp11, Mmus\Tcp11l1, Mmus\Tcp11l2" "Hsap\TCP11L2, Hsap\TCP11X1, Hsap\TCP11X2, Hsap\TCP11, Hsap\TCP11L1" viable FBgn0061101 l(3)S008831b lethal (3) S008831b http://flybase.org/reports/FBgn0061101 gene - - - "0088/31, l(3)S008831b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027263 l(1)G0223 lethal (1) G0223 http://flybase.org/reports/FBgn0027263 - gene - - - l(1)G0223 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001071 Fs(3)Zer Female sterile (3) Zerind http://flybase.org/reports/FBgn0001071 - gene molecular_function ; GO:0003674 | no biological data available meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Zer, Fs(3)Zerind, Fs(3)Sz25, Fs(3)Zer" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,meiotic cell cycle defective" "female pronucleus | maternal effect,pronucleus | maternal effect" FBgn0011104 l(1)Q65 lethal (1) Q65 http://flybase.org/reports/FBgn0011104 FBgn0010210 gene - - - l(1)Q65 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020243 ziti ziti http://flybase.org/reports/FBgn0020243 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available ziti - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019637 Atu Another transcription unit http://flybase.org/reports/FBgn0019637 FBgn0011015 protein_coding_gene RNA polymerase II C-terminal domain phosphoserine binding ; GO:1990269 | inferred from biological aspect of ancestor with PANTHER:PTN000567381 histone modification ; GO:0016570 | inferred from electronic annotation with InterPro:IPR007149 positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from biological aspect of ancestor with PANTHER:PTN000567381 regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype Cdc73/Paf1 complex ; GO:0016593 | inferred from electronic annotation with InterPro:IPR007149 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000567381 "atu, l(3)s1938, CG1433, Atu" IPR007149:Leo1-like protein CG1433 11-Aug-17 DroID_v2017_08 Drer\leo1 Scer\LEO1 Cele\leo-1 Xtro\leo1 Mmus\Leo1 Hsap\LEO1 "lethal,recessive,viable,body color defective" mesothoracic tergum FBgn0030196 Psf3 Psf3 http://flybase.org/reports/FBgn0030196 protein_coding_gene 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype GINS complex ; GO:0000811 | inferred from direct assay "CG2222, Psf3" "IPR010492:GINS complex, subunit Psf3, IPR021151:GINS subunit, domain A" CG2222 11-Aug-17 DroID_v2017_08 Drer\gins3 Scer\PSF3 Cele\psf-3 Xtro\gins3 Mmus\Gins3 Hsap\GINS3 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0032194 CG4901 - http://flybase.org/reports/FBgn0032194 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 helicase activity ; GO:0004386 | inferred from sequence or structural similarity" neurogenesis ; GO:0022008 | inferred from mutant phenotype RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN001053657 "cg4901, CG4901" "IPR001650:Helicase, C-terminal, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR011545:DEAD/DEAH box helicase domain" CG4901 11-Aug-17 DroID_v2017_08 "Drer\dhx40, Drer\dhx33, Drer\dhx34, Drer\dhx8, Drer\dhx15, Drer\dhx16" "Scer\DHR2, Scer\PRP22" "Cele\mog-4, Cele\mog-5, Cele\let-355, Cele\ddx-15, Cele\mog-1" "Xtro\dhx38, Xtro\dhx40, Xtro\dhx33, Xtro\dhx8, Xtro\dhx16, Xtro\ythdc2, Xtro\dhx15, Xtro\dhx34" "Mmus\Dhx15, Mmus\Dhx34, Mmus\Dhx16, Mmus\Dhx38, Mmus\Dhx33, Mmus\Ythdc2, Mmus\Dhx40, Mmus\Dhx8" "Hsap\DHX8, Hsap\DHX33, Hsap\YTHDC2, Hsap\DHX40, Hsap\DHX15, Hsap\DHX34, Hsap\DHX16, Hsap\DHX38" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0040349 CG3699 - http://flybase.org/reports/FBgn0040349 protein_coding_gene "2,4-dienoyl-CoA reductase (NADPH) activity ; GO:0008670 | inferred from sequence or structural similarity with HGNC:2754" fatty acid beta-oxidation ; GO:0006635 | non-traceable author statement - "CT12411, EG:BACR7A4.14, CG3699" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG3699 11-Aug-17 DroID_v2017_08 "Drer\pecr, Drer\dhrs7, Drer\decr1, Drer\decr2, Drer\elovl8a, Drer\zgc:101858, Drer\elovl7a, Drer\elovl4a, Drer\elovl4b, Drer\hsdl2, Drer\elovl1b, Drer\hsd17b14, Drer\hsd17b8, Drer\elovl1a, Drer\cbr4, Drer\bdh2, Drer\elovl7b, Drer\dhrs1, Drer\zgc:113054, Drer\elovl8b, Drer\elovl2, Drer\elovl5" "Scer\OAR1, Scer\IRC24, Scer\YIR035C, Scer\SPS19" "Cele\F12E12.11, Cele\T01G6.1, Cele\F28H7.2, Cele\decr-1.2, Cele\R05D8.9, Cele\F02C12.2, Cele\dhs-15, Cele\C06E4.3, Cele\C01G12.5, Cele\Y47G6A.22, Cele\R05D8.7, Cele\C06E4.6, Cele\decr-1.3, Cele\W03F9.9, Cele\D1054.8, Cele\C06B8.3, Cele\Y47G6A.21, Cele\F26D2.15, Cele\dhs-11, Cele\F25D1.5, Cele\ZK829.1, Cele\T01G6.10, Cele\dhs-25, Cele\F12E12.12, Cele\dhs-14" "Xtro\elovl7, Xtro\dhrs4, Xtro\cbr4, Xtro\hsdl2, Xtro\MGC147226, Xtro\elovl2, Xtro\MGC79752, Xtro\elovl5, Xtro\pecr, Xtro\decr1, Xtro\decr2, Xtro\elovl1, Xtro\hsd17b8, Xtro\hsd17b14, Xtro\dhrs7" "Mmus\Dhrs1, Mmus\Dhrs2, Mmus\Hsdl2, Mmus\Pecr, Mmus\H2-Ke6, Mmus\Elovl4, Mmus\Decr2, Mmus\Elovl2, Mmus\Dhrs4, Mmus\Decr1, Mmus\Dhrs7, Mmus\Bdh2, Mmus\Elovl7, Mmus\Elovl5, Mmus\Hsd17b14, Mmus\Cbr4" "Hsap\HSD17B8, Hsap\DHRS2, Hsap\DHRS4, Hsap\ELOVL4, Hsap\DECR2, Hsap\DHRS4L2, Hsap\ELOVL5, Hsap\DHRS1, Hsap\DHRS7, Hsap\ELOVL7, Hsap\DECR1, Hsap\HSDL2, Hsap\NME4, Hsap\ELOVL1, Hsap\CBR4, Hsap\ELOVL2, Hsap\BDH2, Hsap\HSD17B14, Hsap\PECR" viable FBgn0029762 NAAT1 Nutrient Amino Acid Transporter 1 http://flybase.org/reports/FBgn0029762 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neutral amino acid transmembrane transporter activity ; GO:0015175 | inferred from direct assay cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model L-amino acid transmembrane transporter activity ; GO:0015179 | inferred from direct assay neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT sodium:amino acid symporter activity ; GO:0005283 | inferred from mutant phenotype D-amino acid transmembrane transporter activity ; GO:0042943 | inferred from direct assay neutral amino acid transport ; GO:0015804 | inferred from direct assay neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT D-amino acid transport ; GO:0042940 | inferred from direct assay L-amino acid transport ; GO:0015807 | inferred from direct assay sodium ion transport ; GO:0006814 | inferred from mutant phenotype amino acid transmembrane import ; GO:0044745 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0005283 integral component of membrane ; GO:0016021 | inferred from sequence model "anon-WO0149848.3, CG3252, NAAT1, DmNAT1, dmNAT1" IPR000175:Sodium:neurotransmitter symporter CG3252 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-117c9.5, Drer\slc6a9, Drer\slc6a13, Drer\slc6a13l, Drer\slc6a4b, Drer\si:ch211-132b12.1, Drer\si:ch211-132b12.6, Drer\slc6a2, Drer\slc6a4a, Drer\zgc:174946, Drer\slc6a8, Drer\slc6a6b, Drer\slc6a16b, Drer\slc6a13, Drer\slc6a16a, Drer\slc6a1l, Drer\slc6a11a, Drer\si:ch211-132b12.2, Drer\slc6a5, Drer\slc6a15, Drer\zgc:158225, Drer\slc6a19b, Drer\slc6a1a, Drer\slc6a19a.1, Drer\slc6a14, Drer\slc6a17, Drer\slc6a18, Drer\si:ch211-132b12.3, Drer\slc6a6a, Drer\slc6a1b" - "Cele\snf-5, Cele\mod-5, Cele\snf-6, Cele\dat-1, Cele\snf-7, Cele\snf-11, Cele\snf-2, Cele\snf-9, Cele\snf-12, Cele\snf-3" "Xtro\slc6a14.2, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a17, Xtro\slc6a9, Xtro\slc6a12, Xtro\slc6a8, Xtro\slc6a16, Xtro\slc6a1, Xtro\slc6a19, Xtro\LOC100127682, Xtro\slc6a2, Xtro\slc6a5, Xtro\slc6a3, Xtro\slc6a13, Xtro\slc6a7, Xtro\slc6a15" "Mmus\Slc6a19, Mmus\Slc6a15, Mmus\Slc6a5, Mmus\Slc6a11, Mmus\Slc6a2, Mmus\Slc6a12, Mmus\Slc6a20a, Mmus\Slc6a3, Mmus\Slc6a18, Mmus\Slc6a6, Mmus\Slc6a7, Mmus\Slc6a14, Mmus\Slc6a8, Mmus\Slc6a4, Mmus\Slc6a9, Mmus\Slc6a13, Mmus\Slc6a1, Mmus\Slc6a17, Mmus\Slc6a20b" "Hsap\SLC6A1, Hsap\SLC6A2, Hsap\SLC6A9, Hsap\SLC6A17, Hsap\SLC6A20, Hsap\SLC6A11, Hsap\SLC6A19, Hsap\SLC6A15, Hsap\SLC6A18, Hsap\SLC6A6, Hsap\SLC6A4, Hsap\SLC6A8, Hsap\SLC6A5, Hsap\SLC6A14, Hsap\SLC6A12, Hsap\SLC6A3, Hsap\SLC6A13" viable FBgn0264998 CR44149 - http://flybase.org/reports/FBgn0264998 non_protein_coding_gene - - - "lincRNA.91, CR44149" - CR44149 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031520 CG8837 - http://flybase.org/reports/FBgn0031520 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG8837 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG8837 11-Aug-17 DroID_v2017_08 "Drer\slc2a12, Drer\slc2a10, Drer\LOC101882338, Drer\slc2a8, Drer\slc2a13b, Drer\slc2a6" "Scer\GAL2, Scer\HXT2, Scer\YDR387C, Scer\GEX2, Scer\ITR1, Scer\VBA2, Scer\HXT15, Scer\YFL040W, Scer\AZR1, Scer\ENB1, Scer\HXT9, Scer\MAL11, Scer\HXT3, Scer\GEX1, Scer\HXT7, Scer\HXT5, Scer\STL1, Scer\HXT11, Scer\HXT13, Scer\MPH2, Scer\SGE1, Scer\RGT2, Scer\ITR2, Scer\HXT4, Scer\VBA4, Scer\VBA5, Scer\SNF3, Scer\HXT17, Scer\HXT8, Scer\YDL199C, Scer\MAL31, Scer\VBA3, Scer\HXT14, Scer\MPH3, Scer\YMR279C, Scer\ATR1, Scer\HXT10, Scer\HXT16, Scer\VBA1, Scer\HXT1, Scer\HXT6" Cele\F48E3.2 "Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a12, Xtro\slc2a10" "Mmus\Slc2a13, Mmus\Slc2a10, Mmus\Slc2a8, Mmus\Slc2a6, Mmus\Slc2a12" "Hsap\SLC2A10, Hsap\SLC2A6, Hsap\SLC2A8, Hsap\SLC2A13, Hsap\SLC2A12" viable FBgn0035645 CG5592 - http://flybase.org/reports/FBgn0035645 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR011701" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG5592 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain, IPR011701:Major facilitator superfamily" CG5592 11-Aug-17 DroID_v2017_08 "Drer\zgc:175176, Drer\slc22a7b.3, Drer\zmp:0000001102, Drer\oatx, Drer\slc22a6l, Drer\slc22a7b.1, Drer\sv2, Drer\LOC100334012, Drer\slc22a5, Drer\slc22a7b.2, Drer\LOC101884074, Drer\slc22a21, Drer\slc22a13" "Scer\TPO2, Scer\GIT1, Scer\QDR1, Scer\DTR1, Scer\PHO84, Scer\HXT5, Scer\HXT9, Scer\YHK8, Scer\QDR3, Scer\TPO3, Scer\TPO1, Scer\AQR1, Scer\FLR1, Scer\HXT2, Scer\QDR2" "Cele\Y66D12A.13, Cele\C06H5.6, Cele\oct-1, Cele\T22F7.1, Cele\C53B4.1, Cele\Y57G11C.23, Cele\C46C2.2, Cele\ZK892.3, Cele\B0361.11, Cele\B0252.3, Cele\Y51A2D.18" Xtro\slc22a6 "Mmus\Slc22a16, Mmus\Slc22a20, Mmus\Slc22a27, Mmus\Slc22a14, Mmus\Slc22a7, Mmus\Slc22a21, Mmus\Slc22a30, Mmus\Svop, Mmus\Slc22a4, Mmus\Slc22a26, Mmus\Slc22a22, Mmus\Slc22a2, Mmus\Slc22a19, Mmus\Slc22a29, Mmus\Slc22a28, Mmus\Sv2c, Mmus\Slc22a23, Mmus\Slc22a8, Mmus\Slc22a6, Mmus\Slc22a5" "Hsap\SLC22A12, Hsap\SLC22A24, Hsap\SLC22A14, Hsap\SVOP, Hsap\SLC22A1, Hsap\SLC22A2, Hsap\SLC22A10, Hsap\SLC22A23, Hsap\SLC22A8, Hsap\SLC22A7, Hsap\SLC22A11, Hsap\SLC22A13, Hsap\SLC22A4, Hsap\SV2C, Hsap\SLC22A5, Hsap\SLC22A25, Hsap\SLC22A9, Hsap\SV2B, Hsap\SLC22A6" "partially lethal - majority die,some die during pupal stage" FBgn0266523 Nadsyn::Mmus\Ube4b - http://flybase.org/reports/FBgn0266523 engineered_fusion_gene - - - "CG9940::Mmus\Ube4b, Nadsyn::Mmus\Ube4b" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065459 l(2)SH1382 lethal (2) SH1382 http://flybase.org/reports/FBgn0065459 gene - - - "l(2)SH1382, l(2)SH2 1382" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037004 CG17637 - http://flybase.org/reports/FBgn0037004 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG17637 "IPR001958:Tetracycline resistance protein TetA/multidrug resistance protein MdtG, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG17637 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-87m7.2, Drer\LOC557306, Drer\si:ch211-262i1.4, Drer\LOC100002406, Drer\slc46a3, Drer\slc46a1, Drer\zgc:174356, Drer\hiat1b, Drer\si:dkey-5g14.1, Drer\hiat1a" Scer\YJL163C "Cele\F40F9.5, Cele\C46C11.2, Cele\T25D3.4, Cele\Y4C6B.5, Cele\Y71G12B.25" "Xtro\mfsd14b, Xtro\slc46a1, Xtro\mfsd14a" "Mmus\Slc46a2, Mmus\Mfsd14b, Mmus\Slc46a1, Mmus\Slc46a3, Mmus\Mfsd14a" "Hsap\SLC46A1, Hsap\SLC46A2, Hsap\MFSD14B, Hsap\SLC46A3, Hsap\MFSD14A" FBgn0034540 Lrt Leucine-rich tendon-specific protein http://flybase.org/reports/FBgn0034540 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with robo1 negative regulation of muscle cell chemotaxis toward tendon cell ; GO:2001282 | inferred from mutant phenotype Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell ; GO:2001283 | inferred from genetic interaction with robo1 protein complex ; GO:0043234 | inferred from physical interaction with robo1 muscle tendon junction ; GO:0005927 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "tartan/capricious-like, CT31131, Lrt, CG11136, lrt" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG11136 11-Aug-17 DroID_v2017_08 "Drer\nyx, Drer\flrt1a, Drer\flrt1b, Drer\lrit2, Drer\flrt3, Drer\lrit3b, Drer\lrrc24" Scer\CYR1 "Cele\clec-1, Cele\lron-11" "Xtro\slitrk2, Xtro\slitrk1, Xtro\flrt1, Xtro\LOC100488097, Xtro\flrt3, Xtro\nyx, Xtro\tril" "Mmus\Nyx, Mmus\Flrt1, Mmus\Lrit2, Mmus\Pkd1, Mmus\Flrt3, Mmus\Tril, Mmus\Rtn4rl2, Mmus\Lrrc24, Mmus\Lgi4" "Hsap\LRRC24, Hsap\LRIT2, Hsap\AMIGO2, Hsap\RTN4RL2, Hsap\LRRC70, Hsap\FLRT3, Hsap\PKD1, Hsap\FLRT1, Hsap\NYX" viable "ventral longitudinal muscle,embryonic/larval somatic muscle,A1-7 ventral oblique muscle 4,A1-7 ventral acute muscle 3" DRSC06045 E -0.790561286 0.424615961 -0.107030463 1.665103435 -0.043728304 0.44673536 FBgn0262315 mir-2493 mir-2493 stem loop http://flybase.org/reports/FBgn0262315 miRNA_gene - - - "mir-2493, CR43022, dme-mir-2493, dme-miR-2493-5p" - CR43022 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036998 CG5969 - http://flybase.org/reports/FBgn0036998 protein_coding_gene - vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from electronic annotation with InterPro:IPR019013 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "BcDNA:GM09417, BcDNA:RE53796, CG32426, CG5969" IPR019013:Vacuolar ATPase assembly integral membrane protein Vma21 CG5969 11-Aug-17 DroID_v2017_08 "Drer\qpct, Drer\vma21" Scer\VMA21 "Cele\R07E5.7, Cele\H27A22.1, Cele\pdcd-2" "Xtro\vma21, Xtro\qpct" "Mmus\Qpct, Mmus\Vma21" "Hsap\QPCT, Hsap\QPCTL, Hsap\VMA21" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0085202 CG34173 - http://flybase.org/reports/FBgn0085202 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34173 - CG34173 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262979 CR43287 - http://flybase.org/reports/FBgn0262979 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43287, CG43287" - CR43287 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029740 CG12680 - http://flybase.org/reports/FBgn0029740 protein_coding_gene - - - CG12680 - CG12680 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264395 CG43843 - http://flybase.org/reports/FBgn0264395 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43843, CG15049" - CG43843 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004524 l(4)102EFa lethal (4) 102EFa http://flybase.org/reports/FBgn0004524 - gene - - - "l(4)9, l(4)BU-1, l(4)1-JFC, l(4)102EFa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002043 l(2)37Dg lethal (2) 37Dg http://flybase.org/reports/FBgn0002043 - gene - - - "l(2)OE39, l(2)37Dg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037093 Cdk12 Cyclin-dependent kinase 12 http://flybase.org/reports/FBgn0037093 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 cyclin binding ; GO:0030332 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity cyclin binding ; GO:0030332 | inferred from physical interaction with UniProtKB:Q961D1 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | inferred from sequence or structural similarity with SGD:S000001622 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity with SGD:S000001622 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | inferred from direct assay" positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity phosphorylation of RNA polymerase II C-terminal domain ; GO:0070816 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000001622 phagocytosis ; GO:0006909 | inferred from mutant phenotype phosphorylation of RNA polymerase II C-terminal domain ; GO:0070816 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 polytene chromosome puff ; GO:0005703 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay cyclin/CDK positive transcription elongation factor complex ; GO:0008024 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 nuclear cyclin-dependent protein kinase holoenzyme complex ; GO:0019908 | inferred from direct assay "AC017581, anon-WO0140519.165, gi24668141, CG7597, cg7597, Cdk12, dCDK12, CDK12" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG7597 11-Aug-17 DroID_v2017_08 "Drer\cdk13, Drer\cdk9, Drer\prpf4bb, Drer\akt3b" "Scer\SGV1, Scer\SNF1, Scer\SWE1, Scer\CTK1, Scer\FPK1" "Cele\cdk-12, Cele\cdk-9" "Xtro\cdk12, Xtro\cdk9, Xtro\prpf4b, Xtro\cdk13" "Mmus\Cdk13, Mmus\Cdk9, Mmus\Cdk12, Mmus\Prpf4b" "Hsap\CDK9, Hsap\CDK12, Hsap\CDK13" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC11836 I -2.145831887 3.612852403 1.160552934 -0.263228052 -0.605919049 -0.430251493 FBgn0034198 CG11400 - http://flybase.org/reports/FBgn0034198 protein_coding_gene - - - CG11400 - CG11400 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086901 cv-c crossveinless c http://flybase.org/reports/FBgn0086901 protein_coding_gene "lipid binding ; GO:0008289 | inferred from electronic annotation with InterPro:IPR002913 GTPase activator activity ; GO:0005096 | inferred from genetic interaction with Rac1, Rac2, Rho1 GTPase activator activity ; GO:0005096 | inferred from mutant phenotype" "open tracheal system development ; GO:0007424 | inferred from mutant phenotype spindle localization ; GO:0051653 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype Rho protein signal transduction ; GO:0007266 | inferred from genetic interaction with Rac1, Rac2, Rho1 assembly of actomyosin apparatus involved in cytokinesis ; GO:0000912 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype metaphase/anaphase transition of mitotic cell cycle ; GO:0007091 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype negative regulation of Rho protein signal transduction ; GO:0035024 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with Rho1 epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" cell cortex ; GO:0005938 | inferred by curator from GO:0030866 basolateral plasma membrane ; GO:0016323 | inferred from direct assay "CG34389, cv-c, l(3)06951, CG8480, CG14845, CG31319, CG14848, CG14849, CG31330, CG14847, CG14846, RhoGAP88C, rhoGAP88C, Cv-c" "IPR013761:Sterile alpha motif/pointed domain, IPR000198:Rho GTPase-activating protein domain, IPR002913:START domain, IPR008936:Rho GTPase activation protein, IPR023393:START-like domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG34389 11-Aug-17 DroID_v2017_08 "Drer\dlc1, Drer\si:dkeyp-23e4.3, Drer\arhgap11a, Drer\arhgap28, Drer\stard13b, Drer\arhgap18, Drer\stard8, Drer\stard13a, Drer\si:ch211-247j9.1, Drer\gmip, Drer\zgc:153345" "Scer\BAG7, Scer\LRG1" Cele\gei-1 "Xtro\dlc1, Xtro\gmip, Xtro\arhgap40, Xtro\arhgap11a.2, Xtro\arhgap18, Xtro\stard13, Xtro\arhgap11a.1, Xtro\arhgap28, Xtro\stard8" "Mmus\Arhgap18, Mmus\Arhgap28, Mmus\Dlc1, Mmus\Stard13, Mmus\Gmip, Mmus\Arhgap40, Mmus\Stard8, Mmus\Arhgap11a" "Hsap\ARHGAP18, Hsap\ARHGAP11A, Hsap\STARD13, Hsap\ARHGAP28, Hsap\ARHGAP40, Hsap\GMIP, Hsap\STARD8, Hsap\DLC1" FBgn0065794 l(2)SH0419 lethal (2) SH0419 http://flybase.org/reports/FBgn0065794 gene - - - "l(2)SH0419, l(2)SH2 0419" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065184 l(3)06142b lethal (3) 06142b http://flybase.org/reports/FBgn0065184 gene - - - "l(3)06142, l(3)06142b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053688 CG33688 - http://flybase.org/reports/FBgn0053688 protein_coding_gene molecular_function ; GO:0003674 | no biological data available lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG33688 IPR010512:Protein of unknown function DUF1091 CG33688 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - "viable,visible" chaeta FBgn0043848 412\ORF2 412 element ORF2 http://flybase.org/reports/FBgn0043848 transposable_element_gene - - - "412\ORF2, ORF2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085493 CG40506 - http://flybase.org/reports/FBgn0085493 protein_coding_gene - - - CG40506 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082636 S(CycE[JP])1S3 S(CycE[JP])1S3 http://flybase.org/reports/FBgn0082636 gene - - - "1S3, S(CycE[JP])1S3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043064 Tehao::Tl Tehao::Tl http://flybase.org/reports/FBgn0043064 engineered_fusion_gene - - - Tehao::Tl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014993 l(3)90DEa lethal (3) 90DEa http://flybase.org/reports/FBgn0014993 - gene - - - "l(3)5D4, l(3)90DEa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015969 l(2)55Da lethal (2) 55Da http://flybase.org/reports/FBgn0015969 - gene - - - l(2)55Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025782 anon-MMS91 anon-MMS91 http://flybase.org/reports/FBgn0025782 - gene - - - anon-MMS91 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265256 CG44270 - http://flybase.org/reports/FBgn0265256 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44270, lincRNA.207" - CG44270 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027509 TBCD tubulin folding cofactor D http://flybase.org/reports/FBgn0027509 - protein_coding_gene beta-tubulin binding ; GO:0048487 | inferred from sequence or structural similarity with HGNC:11581 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with HGNC:11581 beta-tubulin binding ; GO:0048487 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 post-chaperonin tubulin folding pathway ; GO:0007023 | inferred from electronic annotation with InterPro:IPR033162 adherens junction assembly ; GO:0034333 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype tubulin complex assembly ; GO:0007021 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype bicellular tight junction assembly ; GO:0070830 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 microtubule cytoskeleton organization involved in mitosis ; GO:1902850 | inferred from genetic interaction with Arl2 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:11581 establishment or maintenance of neuroblast polarity ; GO:0045196 | inferred from genetic interaction with Arl2 protein folding ; GO:0006457 | inferred from sequence or structural similarity with HGNC:11581 negative regulation of microtubule polymerization ; GO:0031115 | inferred from sequence or structural similarity with HGNC:11581 positive regulation of GTPase activity ; GO:0043547 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 lateral plasma membrane ; GO:0016328 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 adherens junction ; GO:0005912 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 bicellular tight junction ; GO:0005923 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 microtubule ; GO:0005874 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 "CG7261, BcDNA:LD22320, TBCD, tbcd" "IPR016024:Armadillo-type fold, IPR022577:Tubulin-specific chaperone D, C-terminal, IPR011989:Armadillo-like helical, IPR033162:Tubulin-folding cofactor D" CG7261 11-Aug-17 DroID_v2017_08 Drer\tbcd Scer\CIN1 Cele\tbcd-1 Xtro\tbcd Mmus\Tbcd Hsap\TBCD "viable,visible" trichogen cell FBgn0035031 CG13587 - http://flybase.org/reports/FBgn0035031 protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from biological aspect of ancestor with PANTHER:PTN000177070 - integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177070 CG13587 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG13587 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-94g1.1, Drer\zgc:162060, Drer\si:dkey-28d5.14, Drer\si:dkey-83f18.11, Drer\si:dkey-28d5.3, Drer\si:dkey-81n2.2, Drer\si:ch211-282j17.11, Drer\si:dkey-88n24.9, Drer\si:dkey-88n24.8, Drer\si:dkey-88n24.10, Drer\mrc1a, Drer\mrc2, Drer\si:ch211-282j17.1, Drer\mrc1b, Drer\si:ch211-272h9.3, Drer\si:dkey-11o15.4, Drer\si:ch211-282j17.3, Drer\LOC101886741, Drer\pla2r1, Drer\si:ch211-63p21.4, Drer\si:dkey-28d5.10, Drer\si:dkey-28d5.12, Drer\si:ch211-282j17.10, Drer\si:dkey-88n24.7, Drer\si:dkey-83f18.7, Drer\si:dkey-83f18.15, Drer\si:ch211-225k7.6, Drer\si:dkey-88n24.6, Drer\si:dkey-83f18.3, Drer\si:ch211-225k7.3, Drer\si:dkey-83f18.9, Drer\si:ch211-225k7.2, Drer\si:ch211-282j17.7, Drer\si:dkey-28d5.4, Drer\si:ch211-225k7.4, Drer\si:dkey-83f18.10, Drer\si:ch211-225k7.5, Drer\si:dkey-81n2.1, Drer\si:dkey-28d5.13, Drer\si:ch73-335d12.2, Drer\si:dkey-192d15.3, Drer\ly75, Drer\si:dkey-83f18.5, Drer\si:dkey-28d5.9, Drer\si:ch211-282j17.8, Drer\LOC101885237, Drer\si:dkey-28d5.8" - "Cele\clec-49, Cele\clec-50, Cele\clec-48" - "Mmus\Mrc1, Mmus\Pla2r1, Mmus\Cd302, Mmus\Mrc2, Mmus\Ly75" "Hsap\REG1A, Hsap\CLEC10A, Hsap\MRC1, Hsap\LY75, Hsap\CD302, Hsap\PLA2R1, Hsap\ASGR1, Hsap\MRC2, Hsap\CLEC4M, Hsap\CLEC17A" viable FBgn0267069 CR45513 - http://flybase.org/reports/FBgn0267069 non_protein_coding_gene - - - CR45513 - CR45513 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034570 CG10543 - http://flybase.org/reports/FBgn0034570 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 gravitaxis ; GO:0042332 | inferred from mutant phenotype - CG10543 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013087:Zinc finger C2H2-type" CG10543 11-Aug-17 DroID_v2017_08 "Drer\LOC100535506, Drer\si:dkeyp-2e4.8, Drer\zgc:174623, Drer\zgc:171422, Drer\si:dkey-253d23.2, Drer\zgc:172128, Drer\zgc:113119, Drer\zgc:113452" Scer\ZAP1 "Cele\let-391, Cele\eor-1, Cele\ztf-23" - - - "gravitaxis defective,viable" FBgn0011172 l(1)291-9 lethal (1) 291-9 http://flybase.org/reports/FBgn0011172 FBgn0010199 gene - - - "291-9, l(1)291-9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085622 CG41336 - http://flybase.org/reports/FBgn0085622 protein_coding_gene - - - CG41336 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034739 CG3927 - http://flybase.org/reports/FBgn0034739 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 RNA binding ; GO:0003723 | inferred from sequence model lateral inhibition ; GO:0046331 | inferred from mutant phenotype nuclear speck ; GO:0016607 | inferred from direct assay "CG3927, cg3927, BcDNA:AT29209" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG3927 11-Aug-17 DroID_v2017_08 "Drer\khdrbs2, Drer\qkib, Drer\khdrbs1b, Drer\qki2, Drer\khdrbs1a, Drer\khdrbs3, Drer\qkia" Scer\MSL5 "Cele\sfa-1, Cele\K07H8.9, Cele\gld-1, Cele\Y57G11C.36, Cele\asd-2, Cele\B0280.11, Cele\F54D1.1" "Xtro\khdrbs3, Xtro\khdrbs2, Xtro\khdrbs1, Xtro\qki" "Mmus\Qk, Mmus\Khdrbs2, Mmus\Sf1, Mmus\Khdrbs1, Mmus\Khdrbs3" "Hsap\KHDRBS2, Hsap\SF1, Hsap\KHDRBS1, Hsap\QKI, Hsap\KHDRBS3" "male fertile,viable,fertile,visible" "chaeta,trichogen cell,supernumerary,tormogen cell" DRSC04433 K -0.088671866 0.721271406 -0.180078422 -0.129856307 0.808576664 -1.84220885 FBgn0039698 CG7789 - http://flybase.org/reports/FBgn0039698 protein_coding_gene - "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550" - CG7789 "IPR000760:Inositol monophosphatase-like, IPR020550:Inositol monophosphatase, conserved site, IPR020583:Inositol monophosphatase, metal-binding site" CG7789 11-Aug-17 DroID_v2017_08 "Drer\bpnt1, Drer\si:ch211-160o17.2" - Cele\bpnt-1 "Xtro\inpp1, Xtro\bpnt1" "Mmus\Inpp1, Mmus\Bpnt1" "Hsap\INPP1, Hsap\IMPAD1, Hsap\BPNT1" FBgn0053270 CG33270 - http://flybase.org/reports/FBgn0053270 protein_coding_gene molecular_function ; GO:0003674 | no biological data available lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG6100, CG14139, CG32084, CG33270" - CG33270 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC10584 K 1.879979195 1.062089543 FBgn0058270 CG40270 - http://flybase.org/reports/FBgn0058270 protein_coding_gene - - - CG40270 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264676 CR43961 - http://flybase.org/reports/FBgn0264676 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43961, CR43961" - CR43961 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266772 CR45237 - http://flybase.org/reports/FBgn0266772 non_protein_coding_gene - - - CR45237 - CR45237 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028523 CG5888 - http://flybase.org/reports/FBgn0028523 protein_coding_gene - - - "BG:DS02780.1, CT18477, CG5888" "IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG5888 11-Aug-17 DroID_v2017_08 "Drer\lrit1b, Drer\LOC100330212, Drer\LOC101882074, Drer\lrit3b, Drer\lrit1a, Drer\lrrc53, Drer\lrit3a, Drer\si:dkey-52j6.3" - "Cele\egg-6, Cele\pan-1, Cele\lron-9" - "Mmus\Lrit1, Mmus\Tril, Mmus\Chadl, Mmus\Lrg1, Mmus\Lrrc26, Mmus\Lrrc52, Mmus\Cpn2, Mmus\Lgr5, Mmus\Lgr6, Mmus\Lrit3" "Hsap\LRIT3, Hsap\LRG1, Hsap\TRIL, Hsap\LGR5, Hsap\LRRC52, Hsap\LRRC26, Hsap\LRIT1, Hsap\CHADL, Hsap\CPN2, Hsap\LGR6" "viable,fertile" FBgn0051262 CG31262 - http://flybase.org/reports/FBgn0051262 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "CG31262, dSLC5A14" IPR001734:Sodium/solute symporter CG31262 11-Aug-17 DroID_v2017_08 "Drer\slc5a8, Drer\slc5a11, Drer\slc5a1, Drer\slc5a3a, Drer\slc5a9, Drer\LOC568338, Drer\si:dkeyp-9d4.5, Drer\slc5a6a, Drer\slc5a5, Drer\slc5a2, Drer\slc5a12, Drer\slc5a8l, Drer\slc5a6b" Scer\DUR3 "Cele\ZK822.5, Cele\F52H2.4" "Xtro\slc5a2, Xtro\slc5a5, Xtro\slc5a11, Xtro\slc5a12, Xtro\slc5a1.1, Xtro\slc5a8, Xtro\slc5a9" "Mmus\Slc5a1, Mmus\Slc5a5, Mmus\Slc5a6, Mmus\Slc5a3, Mmus\Slc5a4a, Mmus\Gm5134, Mmus\Slc5a2, Mmus\Slc5a11, Mmus\Slc5a10, Mmus\Slc5a8, Mmus\Slc5a12, Mmus\Slc5a9, Mmus\Slc5a4b" "Hsap\SLC5A8, Hsap\SLC5A3, Hsap\SLC5A10, Hsap\SLC5A5, Hsap\SLC5A6, Hsap\SLC5A1, Hsap\SLC5A9, Hsap\SLC5A4, Hsap\SLC5A12, Hsap\SLC5A2, Hsap\SLC5A11" DRSC13216 E -1.231515161 0.755300449 2.343924069 0.917808139 -0.487631205 -0.304477817 FBgn0034735 CG4610 - http://flybase.org/reports/FBgn0034735 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000211371 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 mitochondrial tRNA wobble uridine modification ; GO:0070899 | inferred from biological aspect of ancestor with PANTHER:PTN000211372 tRNA methylation ; GO:0030488 | inferred from biological aspect of ancestor with PANTHER:PTN000211371 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000211372 CG4610 "IPR002218:tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related, IPR004416:tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, IPR020595:MnmG-related, conserved site, IPR026904:GidA associated domain 3, IPR023753:FAD/NAD(P)-binding domain" CG4610 11-Aug-17 DroID_v2017_08 Drer\mto1 Scer\MTO1 Cele\mtcu-2 - Mmus\Mto1 Hsap\MTO1 viable DRSC04477 K -0.943990332 0.139024208 -0.083137501 0.79969315 1.618695336 0.119877691 FBgn0010727 l(3)00720 lethal (3) 00720 http://flybase.org/reports/FBgn0010727 - gene - - - "P720, l(3)00720" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031869 CG18304 - http://flybase.org/reports/FBgn0031869 protein_coding_gene - regulation of autophagy ; GO:0010506 | inferred from electronic annotation with InterPro:IPR027881 extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR027881 "CG13774, CG18304" IPR027881:Protein SOGA CG18304 11-Aug-17 DroID_v2017_08 "Drer\soga3, Drer\soga1, Drer\si:ch211-197l9.2, Drer\mtcl1, Drer\soga3b" - Cele\tag-241 "Xtro\soga3, Xtro\soga1" "Mmus\Mtcl1, Mmus\Soga1, Mmus\Soga3" "Hsap\SOGA3, Hsap\SOGA1, Hsap\MTCL1" viable FBgn0027629 ms(1)RA20 ms(1)RA20 http://flybase.org/reports/FBgn0027629 - gene - - - ms(1)RA20 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile spermatocyte FBgn0266770 CR45235 - http://flybase.org/reports/FBgn0266770 non_protein_coding_gene - - - CR45235 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261987 Pxt Peroxinectin-like http://flybase.org/reports/FBgn0261987 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from sequence or structural similarity with UniProtKB:P82600 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 prostaglandin-endoperoxide synthase activity ; GO:0004666 | inferred from sequence model oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 eggshell chorion assembly ; GO:0007306 | inferred from sequence or structural similarity with UniProtKB:P82600 chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype hydrogen peroxide metabolic process ; GO:0042743 | inferred from sequence or structural similarity with UniProtKB:P82600 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype prostaglandin biosynthetic process ; GO:0001516 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "pxt, Pxt, Dpxt, CG7660, anon-WO0172774.128, pxd" "IPR029590:Chorion peroxidase, IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal" CG7660 11-Aug-17 DroID_v2017_08 "Drer\ptgs1, Drer\tpo, Drer\igsf9bb, Drer\ptgs2b, Drer\ptgs2a" - "Cele\pxn-1, Cele\C46A5.4, Cele\T06D8.10, Cele\K10B4.1, Cele\skpo-3, Cele\mlt-7" "Xtro\ptgs1, Xtro\pxdn, Xtro\ptgs2, Xtro\epx, Xtro\mpo, Xtro\tpo" "Mmus\Lpo, Mmus\Mpo, Mmus\Pxdn, Mmus\Ptgs2, Mmus\Ptgs1, Mmus\Tpo, Mmus\Epx" "Hsap\LPO, Hsap\PTGS2, Hsap\PTGS1, Hsap\PXDNL, Hsap\PXDN, Hsap\MPO, Hsap\EPX, Hsap\TPO" FBgn0085489 CG34460 - http://flybase.org/reports/FBgn0085489 protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from sequence model "CG34460, bs26g12.y1, CG6301, bs26g12" IPR029277:Single domain Von Willebrand factor type C domain CG34460 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051506 tRNA:Leu-TAA-1-1 transfer RNA:Leucine-TAA 1-1 http://flybase.org/reports/FBgn0051506 tRNA_gene UUA codon-amino acid adaptor activity ; GO:0033403 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033403 cytosol ; GO:0005829 | inferred by curator from GO:0033403 "AE002708.trna40-LeuTAA, tRNA:L:TAA:AE002708-c, CR31506, chr3R.trna46-LeuTAA, tRNA-Leu-TAA-1-1, tRNA:Leu-TAA-1-1, tRNA:CR31506, UUA" - CR31506 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263513 mir-4953 mir-4953 stem loop http://flybase.org/reports/FBgn0263513 miRNA_gene - - - "mir-4953, CR43616, dme-mir-4953" - CR43616 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265345 CR44299 - http://flybase.org/reports/FBgn0265345 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44299, CR44299" - CR44299 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265364 CR44305 - http://flybase.org/reports/FBgn0265364 non_protein_coding_gene - - - CR44305 - CR44305 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082359 HM165 HM165 http://flybase.org/reports/FBgn0082359 gene - - - HM165 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066114 GlcAT-I GlcAT-I http://flybase.org/reports/FBgn0066114 protein_coding_gene galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ; GO:0015018 | inferred from direct assay glucuronosyltransferase activity ; GO:0015020 | non-traceable author statement carbohydrate metabolic process ; GO:0005975 | inferred from biological aspect of ancestor with PANTHER:PTN000096174 chondroitin sulfate biosynthetic process ; GO:0030206 | non-traceable author statement proteoglycan biosynthetic process ; GO:0030166 | non-traceable author statement heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement chondroitin sulfate metabolic process ; GO:0030204 | inferred from biological aspect of ancestor with PANTHER:PTN000855563 chondroitin sulfate proteoglycan biosynthetic process ; GO:0050650 | inferred from biological aspect of ancestor with PANTHER:PTN000855563 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005027 "DmGlcAT-I, CAA21824, DGlcAT-I, RE38067, EG:EG0007.5, CG32775, BcDNA:GH05057, GlcAT-I, GlcAT1, GH05057p, dGlcAT-I" "IPR005027:Glycosyl transferase, family 43, IPR029044:Nucleotide-diphospho-sugar transferases" CG32775 11-Aug-17 DroID_v2017_08 "Drer\b3gat1b, Drer\b3gat2, Drer\b3gat1a, Drer\b3gat3" - "Cele\glct-3, Cele\glct-1, Cele\glct-4, Cele\sqv-8, Cele\glct-6, Cele\glct-2, Cele\glct-5" "Xtro\b3gat1, Xtro\b3gat3, Xtro\b3gat2" "Mmus\B3gat1, Mmus\B3gat3, Mmus\B3gat2" "Hsap\B3GAT2, Hsap\B3GAT3, Hsap\B3GAT1" embryonic stage -- adult stage "viable,fertile" FBgn0060584 l(3)S094405b lethal (3) S094405b http://flybase.org/reports/FBgn0060584 gene - - - "0944/05, l(3)S094405b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010821 l(3)03847 lethal (3) 03847 http://flybase.org/reports/FBgn0010821 - gene - - - l(3)03847 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011959 tRNA:Arg-ACG-1-10 transfer RNA:Arginine-ACG 1-10 http://flybase.org/reports/FBgn0011959 "FBgn0003758, FBgn0011947, FBgn0051581, FBgn0060097" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "tRNA[arg], tRNA[Arg][[2]], AE002708.trna62-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002708-a, CR31581, tRNA:arg2:84Fa, chr3R.trna68-ArgACG, tRNA-Arg-ACG-1-10, tRNA:Arg-ACG-1-10, tRNA:R2:84Fa, CGU" - CR31581 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002002 l(2)36Ba lethal (2) 36Ba http://flybase.org/reports/FBgn0002002 FBgn0010489 gene - - - "l(2)HT-4, l(2L)HT-4, l(2)01433, l(2)36Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053370 5SrRNA:CR33370 5SrRNA:CR33370 http://flybase.org/reports/FBgn0053370 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33370, 5SrRNA:CR33370" - CR33370 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053441 5SrRNA:CR33441 5SrRNA:CR33441 http://flybase.org/reports/FBgn0053441 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33441, 5SrRNA:CR33441" - CR33441 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0277427 l(3)psg20 - http://flybase.org/reports/FBgn0277427 gene - - - "l(3)psg20, psg20" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022266 l(2)k00609 lethal (2) k00609 http://flybase.org/reports/FBgn0022266 - gene - - - l(2)k00609 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020283 l(3)10532 lethal (3) 10532 http://flybase.org/reports/FBgn0020283 - gene - - - l(3)10532 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004685 l(1)Mc51 lethal (1) Mc51 http://flybase.org/reports/FBgn0004685 - gene - - - l(1)Mc51 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing,somatic clone,wing hair" FBgn0024307 SS3-1 Suppressor of GMR-sina 3-1 http://flybase.org/reports/FBgn0024307 - gene - - - SS3-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070009 BG01367 BG01367 http://flybase.org/reports/FBgn0070009 gene - - - BG01367 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0016829 l(1)MZ16 lethal (1) MZ16 http://flybase.org/reports/FBgn0016829 - gene - - - "l(1)MZ16, M16" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030162 CG1986 - http://flybase.org/reports/FBgn0030162 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available CG1986 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG1986 11-Aug-17 DroID_v2017_08 "Drer\lipib, Drer\lipca, Drer\lipg, Drer\LOC100331214, Drer\pla1a, Drer\LOC101884800, Drer\lpl, Drer\lipia" - - "Xtro\lpl, Xtro\lipg" "Mmus\Lpl, Mmus\Pnlip, Mmus\Lipi, Mmus\Lipg, Mmus\Liph, Mmus\Lipc, Mmus\Pla1a, Mmus\Pnliprp1, Mmus\Pnliprp2" "Hsap\PNLIPRP2, Hsap\PLA1A, Hsap\PNLIPRP3, Hsap\LIPC, Hsap\LIPH, Hsap\LPL, Hsap\LIPG, Hsap\PNLIP, Hsap\PNLIPRP1, Hsap\LIPI" FBgn0060850 l(3)S048518 lethal (3) S048518 http://flybase.org/reports/FBgn0060850 gene - - - "0485/18, l(3)S048518" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040932 CG12650 - http://flybase.org/reports/FBgn0040932 protein_coding_gene - - - CG12650 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036568 ATPsynbetaL "ATP synthase, beta subunit-like" http://flybase.org/reports/FBgn0036568 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000003882 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000003882" ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000003882 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P06576 regulation of proton transport ; GO:0010155 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype "mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P06576 lipid particle ; GO:0005811 | inferred from direct assay" "CG5389, ATPB, ATPsynbetaL, ms(3)72Dt" "IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR003593:AAA+ ATPase domain, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005722:ATP synthase, F1 complex, beta subunit, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024034:ATPase, F1/V1 complex, beta/alpha subunit, C-terminal, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site" CG5389 11-Aug-17 DroID_v2017_08 "Drer\zgc:163069, Drer\atp5b" Scer\ATP2 Cele\atp-2 Xtro\atp5b Mmus\Atp5b Hsap\ATP5B "male sterile,long lived,female,RU486 conditional,female semi-fertile,short lived,calorie restriction conditional,viable,fertile" FBgn0020347 anon-47Ea anon-47Ea http://flybase.org/reports/FBgn0020347 - gene - - - "528, anon-47Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034859 CG3520 - http://flybase.org/reports/FBgn0034859 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG3520 "IPR011989:Armadillo-like helical, IPR022542:Domain of unknown function DUF3730, IPR016024:Armadillo-type fold, IPR021392:Focadhesin" CG3520 11-Aug-17 DroID_v2017_08 Drer\focad - - Xtro\focad Mmus\Focad Hsap\FOCAD "viable,fertile" FBgn0005554 l(3)85Fg lethal (3) 85Fg http://flybase.org/reports/FBgn0005554 - gene - - - l(3)85Fg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0027343 fz3 frizzled 3 http://flybase.org/reports/FBgn0027343 FBgn0025619 protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from electronic annotation with InterPro:IPR017981 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt2 inferred from physical interaction with wg Wnt-activated receptor activity ; GO:0042813 | inferred by curator from GO:0017147 transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity "cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR000539, InterPro:IPR017981 establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with fz signal transduction ; GO:0007165 | inferred from sequence or structural similarity" "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000539, InterPro:IPR017981 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | non-traceable author statement" "fz3, CG16785, Dfz3, dfz3, DFz3, EG:34F3.6, dFz3, Dm Fz3, Fz3" "IPR017981:GPCR, family 2-like, IPR000539:Frizzled protein, IPR015526:Frizzled/secreted frizzled-related protein, IPR020067:Frizzled domain, IPR000504:RNA recognition motif domain" CG16785 11-Aug-17 DroID_v2017_08 "Drer\fzd5, Drer\fzd8a, Drer\si:cabz01033205.3, Drer\fzd2, Drer\sfrp1b, Drer\sfrp2l, Drer\fzd10, Drer\sfrp5, Drer\sfrp2, Drer\tlc, Drer\corin, Drer\smo, Drer\fzd9a, Drer\fzd8b, Drer\LOC101884738, Drer\fzd3a, Drer\fzd7a, Drer\fzd7b, Drer\frzb, Drer\fzd3b, Drer\fzd9b, Drer\szl, Drer\sfrp1a" - Cele\sfrp-1 "Xtro\fzd7, Xtro\smo, Xtro\fzd9, Xtro\fzd6, Xtro\fzd5, Xtro\fzd3, Xtro\frzb, Xtro\sfrp1, Xtro\fzd10, Xtro\sfrp2, Xtro\sfrpx, Xtro\fzd8, Xtro\cpz, Xtro\mfrp, Xtro\frzb2, Xtro\sfrp5, Xtro\col18a1, Xtro\corin, Xtro\szl, Xtro\fzd4, Xtro\fzd2" "Mmus\Fzd2, Mmus\Sfrp2, Mmus\Sfrp4, Mmus\Mfrp, Mmus\Corin, Mmus\Cpz, Mmus\Fzd3, Mmus\Fzd8, Mmus\Fzd4, Mmus\Fzd6, Mmus\Smo, Mmus\Frzb, Mmus\Sfrp1, Mmus\Fzd9, Mmus\Sfrp5, Mmus\Fzd10, Mmus\Fzd7, Mmus\Fzd1, Mmus\Fzd5" "Hsap\SFRP1, Hsap\CORIN, Hsap\SFRP2, Hsap\FZD4, Hsap\FZD8, Hsap\FZD1, Hsap\SMO, Hsap\MFRP, Hsap\FZD10, Hsap\FZD9, Hsap\CPZ, Hsap\FZD5, Hsap\SFRP4, Hsap\FZD6, Hsap\SFRP5, Hsap\FZD7, Hsap\FRZB, Hsap\FZD2, Hsap\FZD3" larval stage | third instar " dorsal mesothoracic disc | restricted

, ventral thoracic disc | resticted

, eye-antennal disc | resticted

" "viable,fertile" FBgn0005525 l(2)52ACb lethal (2) 52ACb http://flybase.org/reports/FBgn0005525 - gene - - - l(2)52ACb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036076 CG10427 - http://flybase.org/reports/FBgn0036076 protein_coding_gene - - - CG10427 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025166 l(2)38EFe lethal (2) 38EFe http://flybase.org/reports/FBgn0025166 - gene - - - l(2)38EFe - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal,recessive" FBgn0062575 Mod(var)E1178 Mod(var)E1178 http://flybase.org/reports/FBgn0062575 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1178, Mod(var)E1178" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0058442 CG40442 - http://flybase.org/reports/FBgn0058442 protein_coding_gene - - - CG40442 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041167 anon-A6 anon-A6 http://flybase.org/reports/FBgn0041167 gene - - - "A6, anon-A6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051236 CG31236 - http://flybase.org/reports/FBgn0051236 protein_coding_gene - - - "BcDNA:GM01352, CG31236" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264901 CR44092 - http://flybase.org/reports/FBgn0264901 non_protein_coding_gene - - - CR44092 - CR44092 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083097 bi::org-1 bi::org-1 http://flybase.org/reports/FBgn0083097 engineered_fusion_gene - - - bi::org-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,arista,leg,ectopic,ommatidium,microchaeta,interommatidial bristle" FBgn0040102 lectin-24Db lectin-24Db http://flybase.org/reports/FBgn0040102 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 mannose binding ; GO:0005537 | inferred from direct assay galactose binding ; GO:0005534 | inferred from sequence or structural similarity fucose binding ; GO:0042806 | inferred from direct assay - - "CG2958, AC004371a, AC 004371A, lectin-24Db" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG2958 11-Aug-17 DroID_v2017_08 "Drer\hbl4, Drer\hbl2, Drer\illr1, Drer\hbl3, Drer\zmp:0000000937, Drer\illr3, Drer\LOC101882781, Drer\clec3ba, Drer\colec11, Drer\si:ch73-343l4.8, Drer\clec11a, Drer\si:ch211-125e6.14, Drer\hbl1, Drer\clec3bb" - "Cele\clec-149, Cele\clec-239, Cele\clec-78, Cele\clec-28" "Xtro\colec11, Xtro\clec10a, Xtro\colec10, Xtro\clec3b, Xtro\clec3a" "Mmus\Sftpa1, Mmus\Sftpd, Mmus\Olr1, Mmus\Selp, Mmus\Clec4g, Mmus\Clec4e, Mmus\Clec3b, Mmus\Clec10a, Mmus\Fcer2a, Mmus\Clec12b, Mmus\Klra17, Mmus\Mgl2, Mmus\Clec4a2, Mmus\Cd209b, Mmus\Clec11a, Mmus\Mbl2, Mmus\Clec1b, Mmus\Clec4a1, Mmus\Asgr2, Mmus\Klra9, Mmus\Klra4, Mmus\Clec4f, Mmus\Klra2, Mmus\Colec11, Mmus\Colec10, Mmus\Asgr1, Mmus\Cd207, Mmus\Mbl1, Mmus\Klra10" "Hsap\ASGR1, Hsap\CLEC4E, Hsap\ASGR2, Hsap\CLEC2B, Hsap\PRG3, Hsap\SFTPA2, Hsap\CD72, Hsap\COLEC10, Hsap\FCER2, Hsap\OLR1, Hsap\CLEC1B, Hsap\SFTPD, Hsap\KLRC2, Hsap\CLEC4M, Hsap\SFTPA1, Hsap\CLEC3A, Hsap\MBL2, Hsap\CLEC10A, Hsap\COLEC11, Hsap\CLEC1A, Hsap\CLEC3B, Hsap\CLEC4A, Hsap\CLEC4G, Hsap\CLEC4F, Hsap\CLEC11A" viable FBgn0003873 Tu Turned-up wing http://flybase.org/reports/FBgn0003873 - gene - - - Tu - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable" wing FBgn0065892 l(2)SH0217 lethal (2) SH0217 http://flybase.org/reports/FBgn0065892 gene - - - "l(2)SH0217, l(2)SH2 0217" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061494 l(3)18304 lethal (3) 18304 http://flybase.org/reports/FBgn0061494 gene - - - l(3)18304 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic head,germline clone,maternal effect,embryonic thorax,embryonic abdomen,ectopic" FBgn0034554 CG15227 - http://flybase.org/reports/FBgn0034554 protein_coding_gene - - - CG15227 "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class" CG15227 11-Aug-17 DroID_v2017_08 "Drer\ca6, Drer\ca8, Drer\ca16b, Drer\ca4a, Drer\ca10b, Drer\ca5a, Drer\zgc:153760, Drer\ptprga, Drer\ca9, Drer\ca7, Drer\ca12, Drer\ca4c, Drer\ca4b, Drer\ca14, Drer\car15, Drer\ca2, Drer\ca15b, Drer\ca15a, Drer\ca10a, Drer\ca15c, Drer\cahz" - "Cele\cah-5, Cele\cah-3" "Xtro\ca11, Xtro\ca3, Xtro\ca8, Xtro\ca1, Xtro\ca7, Xtro\ca10, Xtro\ca4, Xtro\LOC779564, Xtro\ca2, Xtro\ca12, Xtro\ca14, Xtro\ca6, Xtro\ca5b" "Mmus\Car1, Mmus\Car9, Mmus\Car3, Mmus\Car8, Mmus\Car2, Mmus\Car5b, Mmus\Car5a, Mmus\Car13, Mmus\Car10, Mmus\Car4, Mmus\Ptprg, Mmus\Car7, Mmus\Car15, Mmus\Car11, Mmus\Car6, Mmus\Car12, Mmus\Car14" "Hsap\CA5B, Hsap\CA11, Hsap\CA13, Hsap\CA2, Hsap\CA7, Hsap\CA12, Hsap\CA5A, Hsap\CA4, Hsap\CA6, Hsap\CA1, Hsap\CA10, Hsap\CA9, Hsap\CA8, Hsap\PTPRG, Hsap\CA3, Hsap\CA14" FBgn0024578 l(3)rL203 lethal (3) rL203 http://flybase.org/reports/FBgn0024578 - gene - - - l(3)rL203 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065084 snmRNA:763 small non-messenger RNA 763 http://flybase.org/reports/FBgn0065084 non_protein_coding_gene - - - "Dm-763, CR33711, snmRNA:763" - CR33711 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035056 spz6 spatzle 6 http://flybase.org/reports/FBgn0035056 protein_coding_gene Toll binding ; GO:0005121 | inferred from sequence or structural similarity with spz Toll signaling pathway ; GO:0008063 | inferred from sequence or structural similarity with spz extracellular region ; GO:0005576 | inferred from sequence or structural similarity with spz "BcDNA:LP10725, CG9196, Spz6, spz6, CT26280" IPR029034:Cystine-knot cytokine CG9196 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0040248 anon-49Db anon-49Db http://flybase.org/reports/FBgn0040248 gene - - - "11A, anon-49Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085641 CG41395 - http://flybase.org/reports/FBgn0085641 protein_coding_gene - - - CG41395 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267049 CG45493 - http://flybase.org/reports/FBgn0267049 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45493 - CG45493 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067311 CheB38b Chemosensory protein B 38b http://flybase.org/reports/FBgn0067311 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model "CG9329, 38E.23, CG33321, CheB38b" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster, IPR010512:Protein of unknown function DUF1091" CG33321 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038054 CG5509 - http://flybase.org/reports/FBgn0038054 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5509 - CG5509 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267604 CR45942 - http://flybase.org/reports/FBgn0267604 non_protein_coding_gene - - - CR45942 - CR45942 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053191 CG33191 - http://flybase.org/reports/FBgn0053191 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH01761, BcDNA:GH01761, anon-WO0140519.60, CG33191" - CG33191 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037227 TwdlV TweedleV http://flybase.org/reports/FBgn0037227 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlV, CG14640" IPR004145:Domain of unknown function DUF243 CG14640 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037185 CG11367 - http://flybase.org/reports/FBgn0037185 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR015414 cellular_component ; GO:0005575 | no biological data available CG11367 "IPR015414:Transmembrane protein TMEM64, IPR032816:SNARE associated Golgi protein" CG11367 11-Aug-17 DroID_v2017_08 "Drer\tmem41b, Drer\tmem41ab, Drer\tmem41aa, Drer\tmem64" Scer\TVP38 - "Xtro\tmem64, Xtro\tmem41b" "Mmus\Tmem64, Mmus\Tmem41b, Mmus\Tmem41a" "Hsap\TMEM41A, Hsap\TMEM64, Hsap\TMEM41B" "viable,fertile" FBgn0037213 CG12581 - http://flybase.org/reports/FBgn0037213 protein_coding_gene - - - CG12581 "IPR011993:PH domain-like, IPR006020:PTB/PI domain" CG12581 11-Aug-17 DroID_v2017_08 - - Cele\R148.5 - - - "visible,partially lethal - majority die,some die during pupal stage,viable,body color defective" "trichogen cell,chaeta,supernumerary,mesothoracic tergum" FBgn0037698 CG16779 - http://flybase.org/reports/FBgn0037698 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN001043031" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 histone deacetylase complex ; GO:0000118 | inferred from biological aspect of ancestor with PANTHER:PTN000412838 CG16779 "IPR000949:ELM2 domain, IPR001005:SANT/Myb domain, IPR013087:Zinc finger C2H2-type, IPR009057:Homeobox domain-like, IPR017884:SANT domain, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG16779 11-Aug-17 DroID_v2017_08 "Drer\LOC100535969, Drer\si:dkey-19b23.10, Drer\elmsan1b, Drer\elmsan1a" - "Cele\Y105C5A.1, Cele\saeg-1, Cele\Y73B3A.13, Cele\F28F8.7" "Xtro\elmsan1, Xtro\trerf1" "Mmus\Elmsan1, Mmus\Zfp541, Mmus\Trerf1" "Hsap\ELMSAN1, Hsap\ZNF541, Hsap\TRERF1" viable DRSC15153 K -0.330473416 -1.147200459 0.047791599 -1.104240657 -1.326210351 -3.034568446 FBgn0262708 ifm(2)RS1 - http://flybase.org/reports/FBgn0262708 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0036089 CG14151 - http://flybase.org/reports/FBgn0036089 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14151 IPR031720:Protein of unknown function DUF4728 CG14151 11-Aug-17 DroID_v2017_08 - - Cele\sre-55 - - - "viable,body color defective" mesothoracic tergum DRSC10153 E 0.056923002 -1.327908386 2.299723351 -0.242262893 0.933765552 0.178061266 FBgn0031765 CG9109 - http://flybase.org/reports/FBgn0031765 protein_coding_gene "transferase activity, transferring glycosyl groups ; GO:0016757 | inferred from electronic annotation with InterPro:IPR003378" - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 "CG9109, dC1GalT9" IPR003378:Fringe-like CG9109 11-Aug-17 DroID_v2017_08 "Drer\b3glcta, Drer\b3glctb" - Cele\ZC250.2 Xtro\b3glct Mmus\B3glct Hsap\B3GLCT "lethal,body color defective" mesothoracic tergum FBgn0259465 C495 - http://flybase.org/reports/FBgn0259465 gene - - - C495 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing vein L4" FBgn0039296 CG10420 - http://flybase.org/reports/FBgn0039296 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616 | inferred from sequence or structural similarity with UniProtKB:Q08199" endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q08199 endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN001062495 "CG10420, SIL1" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG10420 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-195b11.7, Drer\hspbp1" "Scer\SIL1, Scer\FES1" - "Xtro\sil1, Xtro\hspbp1" "Mmus\Sil1, Mmus\Hspbp1" "Hsap\SIL1, Hsap\HSPBP1" viable DRSC14242 E 0.528342786 0.257767637 1.952200948 1.30461057 -0.426873822 0.774138065 FBgn0063419 l(3)3450-D lethal (3) 3450-D http://flybase.org/reports/FBgn0063419 gene - - - l(3)3450-D - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0062652 EP374 EP374 http://flybase.org/reports/FBgn0062652 gene - - - "EP(3)0374, EP374" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,scutellum,adult thorax,dorsal" FBgn0034583 CG10527 - http://flybase.org/reports/FBgn0034583 protein_coding_gene farnesoic acid O-methyltransferase activity ; GO:0019010 | NOT inferred from direct assay - cytoplasm ; GO:0005737 | inferred from direct assay "CG10527, FAMeT" "IPR006616:DM9 repeat, IPR024518:Domain of unknown function DUF3421, IPR022041:Farnesoic acid O-methyl transferase" CG10527 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,viable,chemical resistant" FBgn0061080 l(3)S014310b lethal (3) S014310b http://flybase.org/reports/FBgn0061080 gene - - - "0143/10, l(3)S014310b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0003905 ty tiny http://flybase.org/reports/FBgn0003905 - gene - oogenesis ; GO:0048477 | traceable author statement - "l(1)4-103, ty" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,female sterile" "macrochaeta & thorax,eye" FBgn0259753 ms(2)Fra-4 - http://flybase.org/reports/FBgn0259753 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - ms(2)Fra-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "Y chromosome loop,Nebenkern,spermatid,nucleus & spermatid,spermatozoon" FBgn0034911 CG5549 - http://flybase.org/reports/FBgn0034911 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT glycine:sodium symporter activity ; GO:0015375 | inferred from sequence model transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 glycine transport ; GO:0015816 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 CG5549 IPR000175:Sodium:neurotransmitter symporter CG5549 11-Aug-17 DroID_v2017_08 "Drer\slc6a6b, Drer\slc6a9, Drer\slc6a1a, Drer\slc6a16b, Drer\si:ch211-132b12.1, Drer\slc6a15, Drer\slc6a13, Drer\slc6a8, Drer\si:ch211-132b12.6, Drer\si:ch211-132b12.2, Drer\slc6a4b, Drer\slc6a17, Drer\slc6a1l, Drer\slc6a19a.1, Drer\slc6a2, Drer\slc6a11a, Drer\slc6a19b, Drer\slc6a16a, Drer\si:ch211-117c9.5, Drer\slc6a13, Drer\slc6a6a, Drer\si:ch211-132b12.3, Drer\zgc:174946, Drer\slc6a1b, Drer\slc6a13l, Drer\slc6a4a, Drer\zgc:158225, Drer\slc6a14, Drer\slc6a5, Drer\slc6a18" - "Cele\dat-1, Cele\snf-2, Cele\F56F4.3, Cele\snf-6, Cele\snf-7, Cele\mod-5, Cele\snf-9, Cele\snf-11, Cele\C09E8.1, Cele\snf-3, Cele\snf-5" "Xtro\slc6a13, Xtro\slc6a19, Xtro\slc6a2, Xtro\slc6a6, Xtro\slc6a17, Xtro\slc6a14.2, Xtro\slc6a15, Xtro\slc6a12, Xtro\slc6a8, Xtro\LOC100127682, Xtro\slc6a7, Xtro\slc6a1, Xtro\slc6a5, Xtro\slc6a16, Xtro\slc6a3, Xtro\slc6a4, Xtro\slc6a9" "Mmus\Slc6a1, Mmus\Slc6a4, Mmus\Slc6a8, Mmus\Slc6a13, Mmus\Slc6a2, Mmus\Slc6a14, Mmus\Slc6a11, Mmus\Slc6a6, Mmus\Slc6a7, Mmus\Slc6a5, Mmus\Slc6a9, Mmus\Slc6a15, Mmus\Slc6a20a, Mmus\Slc6a3, Mmus\Slc6a12, Mmus\Slc6a18, Mmus\Slc6a17, Mmus\Slc6a20b, Mmus\Slc6a19" "Hsap\SLC6A18, Hsap\SLC6A19, Hsap\SLC6A3, Hsap\SLC6A1, Hsap\SLC6A8, Hsap\SLC6A9, Hsap\SLC6A4, Hsap\SLC6A12, Hsap\SLC6A11, Hsap\SLC6A15, Hsap\SLC6A2, Hsap\SLC6A17, Hsap\SLC6A13, Hsap\SLC6A7, Hsap\SLC6A6, Hsap\SLC6A20, Hsap\SLC6A5, Hsap\SLC6A14" "viable,visible" trichogen cell FBgn0027136 l(3)88EFa lethal (3) 88EFa http://flybase.org/reports/FBgn0027136 - gene - - - l(3)88EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020895 Su(osk)G71 Suppressor of oskar G71 http://flybase.org/reports/FBgn0020895 - gene - - - "G71, Su(osk)G71" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069423 JJF028 JJF028 http://flybase.org/reports/FBgn0069423 gene - - - JJF028 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0035358 CG14949 - http://flybase.org/reports/FBgn0035358 protein_coding_gene - - - CG14949 - CG14949 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262025 CR42836 - http://flybase.org/reports/FBgn0262025 non_protein_coding_gene - - - "CR42836, lincRNA.818" - CR42836 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024998 CG2685 - http://flybase.org/reports/FBgn0024998 - protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:16461 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from biological aspect of ancestor with PANTHER:PTN000331938" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "EG:100G10.1, CG2685" IPR019007:WW domain binding protein 11 CG2685 11-Aug-17 DroID_v2017_08 Drer\wbp11 - "Cele\F33H1.3, Cele\C31G12.4" Xtro\wbp11 Mmus\Wbp11 Hsap\WBP11 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC18463 E -1.496589167 -0.933106189 1.688498094 -1.846632426 0.961629419 1.147872764 FBgn0063391 snoRNA:U14:30Eb snoRNA:U14:30Eb http://flybase.org/reports/FBgn0063391 snoRNA_gene - - - "Dm-396, U14snoRNA, snoRNA:U14:b, CR32876, snoRNA:U14:30Eb" - CR32876 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001458 l(1)7Dl lethal (1) 7Dl http://flybase.org/reports/FBgn0001458 - gene - - - l(1)7Dl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "ovariole,germline clone,egg,maternal effect" FBgn0082933 snoRNA:Me28S-G1083c snoRNA:Me28S-G1083c http://flybase.org/reports/FBgn0082933 snoRNA_gene rRNA 2'-O-ribose methylation guide activity ; GO:0030562 | inferred from sequence model rRNA 2'-O-methylation ; GO:0000451 | inferred from sequence model nucleolus ; GO:0005730 | inferred from direct assay "snoRNA:Me28S-G1083c, Me28S-Gm1083c, CR34564, DmSnR60, DmSnR60c" - CR34564 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266699 CR45189 - http://flybase.org/reports/FBgn0266699 non_protein_coding_gene - - - CR45189 - CR45189 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029582 CG3729 - http://flybase.org/reports/FBgn0029582 protein_coding_gene - - - CG3729 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040545 CG14702 - http://flybase.org/reports/FBgn0040545 protein_coding_gene - - - CG14702 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046667 anon-38C.3 anon-38C.3 http://flybase.org/reports/FBgn0046667 gene - - - "38C.3, anon-38C.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000143 at arctus oculus http://flybase.org/reports/FBgn0000143 - gene - - - at - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,good,fertile" eye FBgn0051826 CG31826 - http://flybase.org/reports/FBgn0051826 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "CG13241, BG:DS09217.6, CG31826" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG31826 11-Aug-17 DroID_v2017_08 "Drer\ttpa, Drer\sec14l7, Drer\rlbp1a, Drer\sec14l8, Drer\ttpal, Drer\clvs2" "Scer\SFH5, Scer\SEC14, Scer\YKL091C" - "Xtro\mospd2, Xtro\sec14l5, Xtro\clvs2, Xtro\ttpa, Xtro\rlbp1, Xtro\clvs1, Xtro\ttpal, Xtro\sec14l1, Xtro\sec14l3" "Mmus\Sec14l2, Mmus\Ttpal, Mmus\Sec14l1, Mmus\Sec14l3, Mmus\Rlbp1, Mmus\Sec14l4, Mmus\Ttpa, Mmus\Clvs2, Mmus\Sec14l5, Mmus\Clvs1" "Hsap\RLBP1, Hsap\CLVS1, Hsap\CLVS2, Hsap\TTPAL, Hsap\SEC14L1, Hsap\SEC14L4, Hsap\TTPA, Hsap\SEC14L6, Hsap\SEC14L3, Hsap\SEC14L5, Hsap\SEC14L2" viable FBgn0263401 CG43447 - http://flybase.org/reports/FBgn0263401 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43447, lincRNA.869" - CG43447 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034838 CG12782 - http://flybase.org/reports/FBgn0034838 protein_coding_gene - - - CG12782 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG12782 11-Aug-17 DroID_v2017_08 Drer\rae1 "Scer\GLE2, Scer\BUB3" Cele\rae-1 Xtro\rae1 Mmus\Rae1 Hsap\RAE1 viable FBgn0022810 E(faf)bE160 Enhancer of faf bE160 http://flybase.org/reports/FBgn0022810 - gene - - - E(faf)bE160 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264445 CR43863 - http://flybase.org/reports/FBgn0264445 non_protein_coding_gene - - - CR43863 - CR43863 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036993 CG5910 - http://flybase.org/reports/FBgn0036993 protein_coding_gene - - - "CK02563, CG5910" - CG5910 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0035121 Tudor-SN Tudor staphylococcal nuclease http://flybase.org/reports/FBgn0035121 protein_coding_gene nuclease activity ; GO:0004518 | inferred from direct assay gene silencing by RNA ; GO:0031047 | inferred from electronic annotation with InterPro:IPR016685 spermatogenesis ; GO:0007283 | inferred from mutant phenotype RNA catabolic process ; GO:0006401 | inferred from biological aspect of ancestor with PANTHER:PTN000266556 negative regulation of transposition ; GO:0010529 | inferred from genetic interaction with piwi nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay RISC complex ; GO:0016442 | inferred from direct assay "TSN, TSN-1, CG7008, Tudor-SN, tudor-SN, TUDOR-SN, p100, SND1, dP100" "IPR002999:Tudor domain, IPR016071:Staphylococcal nuclease (SNase-like), OB-fold, IPR016685:RNA-induced silencing complex, nuclease component Tudor-SN" CG7008 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-93d12.1, Drer\tdrd7a, Drer\stk31, Drer\snd1" Scer\LCL3 Cele\tsn-1 Xtro\snd1 "Mmus\Stk31, Mmus\Snd1, Mmus\Tdrd6" "Hsap\TDRD6, Hsap\SND1, Hsap\TDRD15, Hsap\STK31, Hsap\TDRD5" "viable,fertile" FBgn0037566 mRpL1 mitochondrial ribosomal protein L1 http://flybase.org/reports/FBgn0037566 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049632 box H/ACA snoRNA binding ; GO:0034513 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 structural constituent of ribosome ; GO:0003735 | traceable author statement snRNA pseudouridine synthesis ; GO:0031120 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 rRNA pseudouridine synthesis ; GO:0031118 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 mitochondrial translation ; GO:0032543 | traceable author statement maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049632 cleavage involved in rRNA processing ; GO:0000469 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 box H/ACA snoRNP complex ; GO:0031429 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049632 "L1, CG7494, mRpL1" "IPR005879:Ribosomal protein L1, mitochondrial, IPR016095:Ribosomal protein L1, 3-layer alpha/beta-sandwich, IPR028364:Ribosomal protein L1/ribosomal biogenesis protein, IPR023674:Ribosomal protein L1-like" CG7494 11-Aug-17 DroID_v2017_08 Drer\mrpl1 "Scer\NHP2, Scer\PLM2, Scer\MRPL1" Cele\mrpl-1 Xtro\mrpl1 Mmus\Mrpl1 Hsap\MRPL1 "viable,fertile,visible" trichogen cell DRSC16251 I -1.85613842 -0.653112708 -0.926021638 -0.212620155 0.304789144 1.146192678 FBgn0069971 CG40496 - http://flybase.org/reports/FBgn0069971 protein_coding_gene - - - CG40496 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024358 ES2-1 Enhancer of GMR-sina 2-1 http://flybase.org/reports/FBgn0024358 - gene - - - ES2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036732 Oatp74D Organic anion transporting polypeptide 74D http://flybase.org/reports/FBgn0036732 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with Oatp58Db active transmembrane transporter activity ; GO:0022804 | inferred from sequence or structural similarity with Oatp58Db organic substance transport ; GO:0071702 | inferred from sequence or structural similarity with Oatp58Db integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Oatp58Db intracellular organelle ; GO:0043229 | inferred from direct assay "CG7571, oatp 74D, Oatp74D" "IPR020846:Major facilitator superfamily domain, IPR004156:Organic anion transporter polypeptide OATP, IPR002350:Kazal domain" CG7571 11-Aug-17 DroID_v2017_08 "Drer\slco5a1, Drer\slco1f1, Drer\slco2b1, Drer\slco4a1, Drer\LOC570448, Drer\LOC101883455, Drer\slco1d1, Drer\LOC100334356, Drer\slco1f4, Drer\slco1c1, Drer\slco1f3, Drer\slco3a1, Drer\LOC100536648, Drer\slco1f2, Drer\slco2a1" - "Cele\Y32F6B.1, Cele\F21G4.1, Cele\F47E1.2, Cele\F47E1.4" "Xtro\slco1b3, Xtro\slco3a1, Xtro\slco4c1, Xtro\slco5a1, Xtro\slco2a1, Xtro\slco4a1" "Mmus\Slco2a1, Mmus\Slco1a5, Mmus\Slco2b1, Mmus\Slco4c1, Mmus\Slco1a1, Mmus\Slco1a6, Mmus\Slco1a4, Mmus\Slco4a1, Mmus\Gm5724, Mmus\Slco6d1, Mmus\Slco3a1, Mmus\Slco1b2, Mmus\Slco1c1, Mmus\Gm6614, Mmus\Slco5a1, Mmus\Slco6c1" "Hsap\SLCO5A1, Hsap\SLCO1B7, Hsap\SLCO1B3, Hsap\SLCO2A1, Hsap\SLCO6A1, Hsap\SLCO3A1, Hsap\SLCO1B1, Hsap\SLCO1A2, Hsap\SLCO1C1, Hsap\SLCO2B1, Hsap\SLCO4C1, Hsap\SLCO4A1" "viable,visible" mesothoracic tergum FBgn0011952 tRNA:Arg-TCG-2-1 transfer RNA:Arginine-TCG 2-1 http://flybase.org/reports/FBgn0011952 "FBgn0011947, FBgn0052624, FBgn0060083" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna1-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-a, CR32624, tRNA:arg12Ee, chrX.trna5-ArgTCG, tRNA-Arg-TCG-2-1, tRNA:Arg-TCG-2-1, tRNA:R:12Ee, CGA" - CR32624 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030124 CG12667 - http://flybase.org/reports/FBgn0030124 protein_coding_gene - - - CG12667 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263572 mir-4981 mir-4981 stem loop http://flybase.org/reports/FBgn0263572 miRNA_gene - - - "mir-4981, dme-mir-4981, CR43557" - CR43557 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023446 dre dark red http://flybase.org/reports/FBgn0023446 - gene - - - "dr, dre" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible pigment cell FBgn0001676 l(1)EN13 lethal (1) from Eugene Nonautonomous 13 http://flybase.org/reports/FBgn0001676 - gene - - - l(1)EN13 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030806 CG13001 - http://flybase.org/reports/FBgn0030806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available nervous system development ; GO:0007399 | inferred from sequence or structural similarity with HGNC:24931 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:24931 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24931 CG13001 "IPR018482:Zinc finger, C4H2-type" CG13001 11-Aug-17 DroID_v2017_08 Drer\zc4h2 - "Cele\ZK930.2, Cele\vab-23" Xtro\zc4h2 Mmus\Zc4h2 Hsap\ZC4H2 viable FBgn0065595 l(2)SH0892 lethal (2) SH0892 http://flybase.org/reports/FBgn0065595 gene - - - "l(2)SH0892, l(2)SH2 0892" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065815 l(2)SH0379 lethal (2) SH0379 http://flybase.org/reports/FBgn0065815 gene - - - l(2)SH0379 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260777 CG42571 - http://flybase.org/reports/FBgn0260777 protein_coding_gene - - - "CG42571, chr3L.16.093a" - CG42571 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013587 l(3)97Db lethal (3) 97Db http://flybase.org/reports/FBgn0013587 - gene - - - "l(3)155, l(3)97Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0045863 blood\sORF blood element sORF http://flybase.org/reports/FBgn0045863 transposable_element_gene - - - blood\sORF - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029118 Sucb Sucb http://flybase.org/reports/FBgn0029118 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR013815, InterPro:IPR013816 succinate-CoA ligase (GDP-forming) activity ; GO:0004776 | inferred from sequence or structural similarity with UniProtKB:Q96I99" succinyl-CoA metabolic process ; GO:0006104 | inferred from electronic annotation with InterPro:IPR034722 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:Q96I99 adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype succinate-CoA ligase complex (GDP-forming) ; GO:0045244 | inferred from sequence or structural similarity with UniProtKB:Q96I99 lipid particle ; GO:0005811 | inferred from direct assay "142911_at, sucB, sucb, CG10622, Sucb, G-Sbeta" "IPR005809:Succinate--CoA synthetase, beta subunit, IPR005811:ATP-citrate lyase/succinyl-CoA ligase, IPR013650:ATP-grasp fold, succinyl-CoA synthetase-type, IPR013815:ATP-grasp fold, subdomain 1, IPR016102:Succinyl-CoA synthetase-like, IPR017866:Succinyl-CoA synthetase, beta subunit, conserved site, IPR034722:Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial" CG10622 11-Aug-17 DroID_v2017_08 "Drer\suclg2, Drer\sucla2" Scer\LSC2 "Cele\suca-1, Cele\sucg-1" "Xtro\suclg2, Xtro\sucla2" "Mmus\Sucla2, Mmus\Suclg2" "Hsap\SUCLG2, Hsap\SUCLA2" viable DRSC11294 K 1.405500056 0.080852975 0.703715679 -0.10521442 -0.050090907 1.520624111 FBgn0030930 GalNAc-T2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 http://flybase.org/reports/FBgn0030930 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement endomembrane system ; GO:0012505 | inferred from direct assay "pgant7, CG6394, dGalNAc-T2, anon-WO02059370.15, GalNAc-T2, PGANT7" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG6394 11-Aug-17 DroID_v2017_08 "Drer\galnt16, Drer\galnt11, Drer\galnt3, Drer\galnt10, Drer\LOC103910015, Drer\wbscr17, Drer\LOC100535692, Drer\LOC100334784, Drer\galnt7, Drer\si:ch211-15e22.3, Drer\galnt2, Drer\galnt8a.1, Drer\LOC101882942, Drer\galnt9, Drer\galnt1, Drer\LOC568645, Drer\galnt6, Drer\galnt13, Drer\galnt18b, Drer\galnt14, Drer\galnt8b, Drer\LOC101886587, Drer\poc1bl, Drer\galnt12" - "Cele\gly-7, Cele\gly-11, Cele\gly-9, Cele\gly-3, Cele\gly-10" "Xtro\galnt6.1, Xtro\galnt7, Xtro\galnt15, Xtro\galnt16, Xtro\wbscr17, Xtro\galnt13, Xtro\galnt4, Xtro\galnt10, Xtro\galnt14, Xtro\galnt2, Xtro\galnt9, Xtro\galnt12, Xtro\galnt1" "Mmus\Galnt3, Mmus\Galnt18, Mmus\Galntl6, Mmus\Galnt1, Mmus\Galnt7, Mmus\Galnt12, Mmus\Galnt9, Mmus\Galnt13, Mmus\Galntl5, Mmus\Galnt2, Mmus\Galnt15, Mmus\Galnt16, Mmus\Galnt14, Mmus\Galnt11, Mmus\Galnt5, Mmus\Galnt4, Mmus\Galnt6, Mmus\Wbscr17, Mmus\Galnt10" "Hsap\GALNT15, Hsap\WBSCR17, Hsap\GALNT3, Hsap\GALNT18, Hsap\GALNT6, Hsap\GALNT4, Hsap\GALNT16, Hsap\GALNT5, Hsap\GALNT10, Hsap\GALNT13, Hsap\GALNTL5, Hsap\GALNT2, Hsap\GALNT8, Hsap\GALNT7, Hsap\GALNT1, Hsap\GALNT12, Hsap\GALNTL6, Hsap\POC1B-GALNT4, Hsap\GALNT11, Hsap\GALNT9, Hsap\GALNT14" "viable,fertile,lethal,partially lethal - majority die" FBgn0026441 ear ENL/AF9-related http://flybase.org/reports/FBgn0026441 FBgn0038317 protein_coding_gene "transcription factor activity, core RNA polymerase II binding ; GO:0000991 | inferred from sequence or structural similarity with SGD:S000006050" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR005033 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with HGNC:7136 inferred from sequence or structural similarity with SGD:S000005051 inferred from sequence or structural similarity with SGD:S000006050" ELL-EAF complex ; GO:0032783 | inferred from physical interaction with Su(Tpl) inferred from physical interaction with Su(Tpl) inferred from physical interaction with Su(Tpl) inferred from physical interaction with Su(Tpl) transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with HGNC:7136 inferred from sequence or structural similarity with SGD:S000005051 inferred from sequence or structural similarity with SGD:S000006050 transcription factor TFIIF complex ; GO:0005674 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with SGD:S000006050 "ENL/AF-9, CG4913, ENL/AF9, dENL/AF9, ear, Ear" IPR005033:YEATS CG4913 11-Aug-17 DroID_v2017_08 "Drer\yeats2, Drer\mllt1a, Drer\yeats4, Drer\mllt1b, Drer\mllt3" "Scer\FYV8, Scer\SAS5, Scer\TAF14, Scer\YAF9" - "Xtro\mllt3, Xtro\mllt1, Xtro\yeats2, Xtro\yeats4" "Mmus\Yeats4, Mmus\Mllt3, Mmus\Yeats2, Mmus\Mllt1" "Hsap\YEATS2, Hsap\MLLT3, Hsap\YEATS4, Hsap\MLLT1" viable DRSC15675 E 1.017548008 0.815218848 2.45208999 1.647138559 -1.044325768 -0.264757704 FBgn0065205 l(2)SH2280 lethal (2) SH2280 http://flybase.org/reports/FBgn0065205 gene - - - "l(2)SH2280, l(2)SH2 2280" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265821 CR44610 - http://flybase.org/reports/FBgn0265821 non_protein_coding_gene - - - CR44610 - CR44610 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015000 betaggt-I beta subunit of type I geranylgeranyl transferase http://flybase.org/reports/FBgn0015000 - protein_coding_gene CAAX-protein geranylgeranyltransferase activity ; GO:0004662 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000206684 protein geranylgeranyltransferase activity ; GO:0004661 | inferred from sequence or structural similarity with protein_id:AAA35888.1 inferred from sequence or structural similarity with protein_id:CAA78143.1 neurogenesis ; GO:0022008 | inferred from mutant phenotype protein geranylgeranylation ; GO:0018344 | inferred from biological aspect of ancestor with PANTHER:PTN000206684 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D CAAX-protein geranylgeranyltransferase complex ; GO:0005953 | inferred from biological aspect of ancestor with PANTHER:PTN000206684 "GGT1, beta GGT-I, beta-GGT, betaGGT-I, ggt1, SR2-2, betaggt-I, ggt-1, CG3469, bro3, betaGGTI, ggt-I, betaggt, betaGGT" "IPR001330:PFTB repeat, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid" CG3469 11-Aug-17 DroID_v2017_08 Drer\pggt1b "Scer\BET2, Scer\CDC43" Cele\Y48E1B.3 Xtro\pggt1b Mmus\Pggt1b Hsap\PGGT1B "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic pericardial cell,cardioblast,embryonic/larval neuroblast,ganglion mother cell" FBgn0041099 ppo poco pelo http://flybase.org/reports/FBgn0041099 gene - - - "EP2478, ppo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,wild-type,recessive,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage" "macrochaeta,microchaeta,thecogen cell,ectopic,tormogen cell,trichogen cell,wing margin,scutellum,wing margin bristle,supernumerary,somatic clone,adult thoracic sensillum" FBgn0001805 l(1)Mc35 lethal (1) Mc35 http://flybase.org/reports/FBgn0001805 - gene - - - l(1)Mc35 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031045 CG14212 - http://flybase.org/reports/FBgn0031045 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000467154 pyrophosphatase activity ; GO:0016462 | inferred from sequence or structural similarity with HGNC:16815 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14212, CG14122, 19527979" "IPR006384:Pyridoxal phosphate phosphatase-related, IPR016965:Phosphatase PHOSPHO-type, IPR023214:HAD-like domain" CG14212 11-Aug-17 DroID_v2017_08 "Drer\phospho2, Drer\phospho1" - "Cele\irld-56, Cele\irld-39, Cele\irld-64, Cele\irld-49, Cele\irld-67, Cele\irld-60, Cele\hpa-1, Cele\irld-51" Xtro\phospho2 "Mmus\Phospho1, Mmus\Phospho2" "Hsap\PHOSPHO2, Hsap\PHOSPHO1" "viable,fertile" FBgn0264551 CR43930 - http://flybase.org/reports/FBgn0264551 non_protein_coding_gene - - - CR43930 - CR43930 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002107 l(2)64 lethal (2) 64 http://flybase.org/reports/FBgn0002107 - gene - - - l(2)64 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082669 GS2143 GS2143 http://flybase.org/reports/FBgn0082669 gene - - - GS2143 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027514 CG1024 - http://flybase.org/reports/FBgn0027514 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BcDNA:LD21969, CG1024" "IPR013087:Zinc finger C2H2-type, IPR022755:Zinc finger, double-stranded RNA binding" CG1024 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-154p10.3, Drer\ctcf" Scer\PZF1 - - "Mmus\Ctcf, Mmus\Ctcfl" "Hsap\CTCFL, Hsap\CTCF" "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC12496 K 1.282010376 -0.715777293 1.405237754 -1.309526606 -2.017089235 -0.674651051 FBgn0035239 CG18170 - http://flybase.org/reports/FBgn0035239 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32316, CG18170" "IPR032106:2-oxoglutarate dehydrogenase E1 component, N-terminal domain" CG18170 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036791 CG7271 - http://flybase.org/reports/FBgn0036791 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG7271 IPR013087:Zinc finger C2H2-type CG7271 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250744 l(3)S139908 lethal (3) S139908 http://flybase.org/reports/FBgn0250744 gene - - - "l(3)S139908, l(3)s139908" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0067358 l(3)4106 lethal (3) 4106 http://flybase.org/reports/FBgn0067358 gene - - - l(3)4106 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020327 anon-72Da anon-72Da http://flybase.org/reports/FBgn0020327 - gene - - - "5B3, anon-72Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034712 CG3264 - http://flybase.org/reports/FBgn0034712 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG3264 "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG3264 11-Aug-17 DroID_v2017_08 "Drer\alpi.1, Drer\alp3, Drer\alpi.2, Drer\alpl" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1" "Mmus\Akp3, Mmus\Alpl, Mmus\Alppl2, Mmus\Alpi" "Hsap\ALPL, Hsap\ALPPL2, Hsap\ALPI, Hsap\ALPP" viable FBgn0261864 lzb lazybones http://flybase.org/reports/FBgn0261864 gene - larval foraging behavior ; GO:0035177 | inferred from mutant phenotype - lzb - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0034173 CG9010 - http://flybase.org/reports/FBgn0034173 protein_coding_gene "oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor ; GO:0016620 | inferred from electronic annotation with InterPro:IPR006424, InterPro:IPR020828, InterPro:IPR020829, InterPro:IPR020830, InterPro:IPR020831 NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR006424 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006424" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006424, InterPro:IPR020828, InterPro:IPR020829, InterPro:IPR020830, InterPro:IPR020831 glucose metabolic process ; GO:0006006 | inferred from electronic annotation with InterPro:IPR006424" - "anon-WO0140519.132, CG9010" "IPR006424:Glyceraldehyde-3-phosphate dehydrogenase, type I, IPR020828:Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain, IPR020829:Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, IPR020830:Glyceraldehyde 3-phosphate dehydrogenase, active site, IPR020831:Glyceraldehyde/Erythrose phosphate dehydrogenase family, IPR016040:NAD(P)-binding domain" CG9010 11-Aug-17 DroID_v2017_08 "Drer\gapdh, Drer\gapdhs" "Scer\TDH2, Scer\TDH3, Scer\TDH1" "Cele\gpd-4, Cele\gpd-1, Cele\gpd-2, Cele\gpd-3" - "Mmus\Gapdh-ps15, Mmus\Pnmal2, Mmus\Gapdhs, Mmus\Gapdh" "Hsap\GAPDH, Hsap\PNMAL2, Hsap\GAPDHS" viable FBgn0266402 CR45042 - http://flybase.org/reports/FBgn0266402 non_protein_coding_gene - - - CR45042 - CR45042 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259647 B0091 - http://flybase.org/reports/FBgn0259647 gene - - - B0091 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0001029 Fs(3)Bak Female sterile (3) Baksa http://flybase.org/reports/FBgn0001029 - gene molecular_function ; GO:0003674 | no biological data available embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Bak, Fs(3)Baksa, Fs(3)Sz3, Fs(3)Bak" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,dominant,maternal effect,some die during embryonic stage" FBgn0086215 jhu2388 - http://flybase.org/reports/FBgn0086215 gene - - - jhu2388 - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic salivary gland,circular visceral muscle primordium" FBgn0050083 CG30083 - http://flybase.org/reports/FBgn0050083 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG30083 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG30083 11-Aug-17 DroID_v2017_08 "Drer\tmprss13a, Drer\si:dkey-21e2.15, Drer\si:dkey-21e2.7, Drer\si:ch211-165b19.9, Drer\LOC100331291, Drer\tmprss13b, Drer\si:dkey-21e2.12, Drer\si:ch211-165b19.5, Drer\gzm3" - "Cele\try-1, Cele\try-3" - "Mmus\Gzmg, Mmus\Klk1b5, Mmus\Gzmd, Mmus\Egfbp2, Mmus\Tmprss11c, Mmus\Gzme, Mmus\Mcpt9, Mmus\Mcpt4, Mmus\Ctsg, Mmus\Tmprss11e, Mmus\Mcpt1, Mmus\Cma2, Mmus\Tmprss11b, Mmus\Prss57, Mmus\Prss40, Mmus\Klk6, Mmus\Gzmc, Mmus\Mcpt8, Mmus\Prss39, Mmus\Gzmf, Mmus\Cma1, Mmus\Tmprss11d, Mmus\Gzmb, Mmus\Prss45" "Hsap\TMPRSS11D, Hsap\CTSG, Hsap\PRSS45, Hsap\GZMB, Hsap\TMPRSS11E, Hsap\CMA1, Hsap\GZMH, Hsap\TMPRSS11B, Hsap\PRSS57" viable FBgn0026201 mog mogura http://flybase.org/reports/FBgn0026201 - gene - - - "mgr, mog" - - 11-Aug-17 DroID_v2017_08 - - - - - - "radiation sensitive,visible" eye FBgn0030055 CG12772 - http://flybase.org/reports/FBgn0030055 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of autophagy ; GO:0010507 | inferred from sequence or structural similarity with HGNC:28991 early endosome ; GO:0005769 | inferred from sequence or structural similarity with HGNC:28991 "CG12772, FBgn 30055" "IPR025258:Putative zinc-RING and/or ribbon, IPR015943:WD40/YVTN repeat-like-containing domain" CG12772 11-Aug-17 DroID_v2017_08 "Drer\rufy2, Drer\def8, Drer\si:ch211-260b17.6, Drer\rundc3ab, Drer\rundc3aa, Drer\rubcn, Drer\snx29, Drer\rundc3b, Drer\rufy1, Drer\plekhm3" - Cele\Y56A3A.16 "Xtro\rufy1, Xtro\snx29, Xtro\rundc3b, Xtro\rundc3a, Xtro\rufy3, Xtro\plekhm3, Xtro\rufy2" "Mmus\Snx29, Mmus\Rufy3, Mmus\Plekhm3, Mmus\Rufy1, Mmus\Def8, Mmus\Rubcnl, Mmus\Rufy2, Mmus\Rubcn, Mmus\Rundc3b, Mmus\Rundc3a" "Hsap\PLEKHM3, Hsap\RUNDC3B, Hsap\RUFY1, Hsap\DEF8, Hsap\RUFY2, Hsap\SNX29, Hsap\RUFY3, Hsap\RUBCN, Hsap\RUBCNL, Hsap\RUNDC3A" "viable,fertile" FBgn0264002 MsR2 Myosuppressin receptor 2 http://flybase.org/reports/FBgn0264002 protein_coding_gene myosuppressin receptor activity ; GO:0035013 | inferred from direct assay G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model myosuppressin receptor activity ; GO:0035013 | inferred from physical interaction with Ms neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ; GO:0007193 | inferred from direct assay larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype behavioral defense response ; GO:0002209 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "DmsR-2, CG43745, CG13802, DmsR, CG13803, DMSR-2, anon-WO0170980.161, anon-WO0170980.160, Dm CG13803, MsR2, DMS-R2, MS-R" "IPR017452:GPCR, rhodopsin-like, 7TM, IPR019427:7TM GPCR, serpentine receptor class w (Srw), IPR000276:G protein-coupled receptor, rhodopsin-like" CG43745 11-Aug-17 DroID_v2017_08 "Drer\gper1, Drer\gpr142" - "Cele\K01A6.6, Cele\Y70C5A.4, Cele\srw-123, Cele\srw-107, Cele\C41G6.16, Cele\srw-35, Cele\srw-24, Cele\srw-44, Cele\srw-130, Cele\srw-31, Cele\srw-98, Cele\dmsr-11, Cele\srw-121, Cele\dmsr-4, Cele\srw-20, Cele\srw-32, Cele\T27C5.10, Cele\dmsr-13, Cele\srw-61, Cele\srw-72, Cele\C09F12.3, Cele\srw-87, Cele\dmsr-2, Cele\srw-134, Cele\srw-141, Cele\srw-10, Cele\srw-14, Cele\T02D1.4, Cele\srw-89, Cele\srw-67, Cele\srw-137, Cele\srw-115, Cele\dmsr-3, Cele\srw-2, Cele\srw-95, Cele\dmsr-15, Cele\dmsr-10, Cele\frpr-13, Cele\srw-60, Cele\dmsr-9, Cele\srw-66, Cele\srw-133, Cele\srw-76, Cele\srw-94, Cele\srw-63, Cele\srw-3, Cele\F38E1.6, Cele\srw-54, Cele\Y75B12B.10, Cele\srw-73, Cele\srw-101, Cele\srw-68, Cele\srw-55, Cele\srw-4, Cele\srw-9, Cele\dmsr-6, Cele\srw-99, Cele\dmsr-1, Cele\srw-33, Cele\srw-40, Cele\T26H8.4, Cele\F09C6.16, Cele\srw-100, Cele\egl-6, Cele\srw-62, Cele\srw-142, Cele\srw-82, Cele\srw-120, Cele\srw-36, Cele\srw-42, Cele\srw-53, Cele\srw-19, Cele\srw-39, Cele\srw-71, Cele\sprr-3, Cele\srw-97, Cele\srw-21, Cele\srw-6, Cele\srw-111, Cele\dmsr-8, Cele\srw-69, Cele\dmsr-14, Cele\srw-108, Cele\srw-90, Cele\dmsr-5, Cele\srw-88, Cele\srw-103, Cele\srw-34, Cele\srw-11, Cele\C47E8.3, Cele\srw-136, Cele\srw-41, Cele\srw-38, Cele\frpr-7, Cele\srw-23, Cele\dmsr-12, Cele\srw-12, Cele\srw-22, Cele\srw-17, Cele\srw-56, Cele\srw-8, Cele\srw-15, Cele\srw-122, Cele\srw-7, Cele\srw-143, Cele\srw-119, Cele\srw-85, Cele\srw-117, Cele\M03F8.7, Cele\srw-16, Cele\srw-26, Cele\srw-75, Cele\srw-1, Cele\srw-139, Cele\srw-29, Cele\srw-51, Cele\dmsr-7, Cele\srw-84, Cele\srw-129, Cele\srw-77, Cele\srw-140, Cele\F13H6.5, Cele\srw-124, Cele\dmsr-16, Cele\C25F9.13, Cele\srw-48, Cele\srw-118, Cele\srw-59, Cele\srw-83, Cele\srw-57, Cele\srw-145, Cele\srw-13, Cele\srw-138, Cele\T26H8.5, Cele\srw-127, Cele\srw-113, Cele\srw-43, Cele\srw-91, Cele\srw-109, Cele\srw-79, Cele\srw-102, Cele\srw-112, Cele\M01G12.6, Cele\srw-144, Cele\srw-30" - "Mmus\Gpr142, Mmus\Gpr139" "Hsap\GPR139, Hsap\GPR142" DRSC22440 E 0.526483414 0.355720274 1.580070182 0.124020341 0.811318223 -0.171148876 FBgn0024620 meso3 meso3 http://flybase.org/reports/FBgn0024620 FBgn0024480 gene - - - "Clone3, meso3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067673 ninja\pol ninja element pol http://flybase.org/reports/FBgn0067673 transposable_element_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR012337" DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - ninja\pol "IPR021109:Aspartic peptidase domain, IPR001584:Integrase, catalytic core, IPR008042:Retrotransposon, Pao, IPR012337:Ribonuclease H-like domain, IPR005312:Protein of unknown function DUF1759, IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002481 l(3)SG38 lethal (3) SG38 http://flybase.org/reports/FBgn0002481 - gene - - - "l(3)m45, l(3)SG38" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,cell cycle" FBgn0003927 snRNA:U3:82E small nuclear RNA U3 at 82E http://flybase.org/reports/FBgn0003927 FBgn0003925 snRNA_gene - - - "snRNA[[2]], K7, snRNA:U3, snRNA3, snRNA2, U3snRNA82E, U3snRNA, snRNA:U3:82E" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051008 CG31008 - http://flybase.org/reports/FBgn0051008 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from sequence or structural similarity with HGNC:21645 mitochondrion organization ; GO:0007005 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with HGNC:21645 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:21645 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:21645 "bs08f11.y1, BEST:GH26101, CG31008" IPR010625:CHCH CG31008 11-Aug-17 DroID_v2017_08 "Drer\chchd2, Drer\chchd10" Scer\MIX17 Cele\har-1 "Xtro\gpat3, Xtro\chchd10" "Mmus\Chchd2, Mmus\Chchd10" "Hsap\CHCHD10, Hsap\CHCHD2" viable FBgn0260593 2L2653 - http://flybase.org/reports/FBgn0260593 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2653 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0052285 tRNA:Lys-CTT-1-12 transfer RNA:Lysine-CTT 1-12 http://flybase.org/reports/FBgn0052285 tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "CR32285, AE002584.trna17-LysCTT, tRNA[Lys][[2]], tRNA:lys2:63B, tRNA:K2:63B, tRNA:K2, tRNA:K:CTT:AE002584-a, chr3L.trna17-LysCTT, tRNA-Lys-CTT-1-12, tRNA:Lys-CTT-1-12, tRNA:CR32285, AAG" - CR32285 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260228 CG42502 - http://flybase.org/reports/FBgn0260228 protein_coding_gene - - - "CG42502, Dromel_CG10570_FBtr0081122_uORF" - CG42502 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263952 BG00907 - http://flybase.org/reports/FBgn0263952 gene - - - BG00907 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0043872 nompE no mechanoreceptor potential E http://flybase.org/reports/FBgn0043872 gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - nompE - - 11-Aug-17 DroID_v2017_08 - - - - - - "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective" "wing,leg,macrochaeta,adult antennal nerve" FBgn0284221 Sema5c Semaphorin 5c http://flybase.org/reports/FBgn0284221 protein_coding_gene metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR024079 embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from expression pattern startle response ; GO:0001964 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype central complex development ; GO:0048036 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002165 "Sema-5C, Sema 5c, CG5661, sema-5c, CT17880, sema 5c, CK02567, BEST:CK02567, BG01245, Sema3A, Dsema3a, Sema-3a, Sema5c, Sema-5c, sema5c" "IPR024079:Metallopeptidase, catalytic domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR001627:Sema domain, IPR002165:Plexin repeat, IPR016201:PSI domain, IPR027231:Semaphorin" CG5661 11-Aug-17 DroID_v2017_08 "Drer\sema4c, Drer\sema4e, Drer\sema3fb, Drer\sema3fa, Drer\sema6a, Drer\sema3e, Drer\sema3c, Drer\sema6d, Drer\sema4f, Drer\si:ch211-168n16.1, Drer\sema4ga, Drer\sema3d, Drer\si:dkey-49n23.1, Drer\sema4ba, Drer\sema6e, Drer\sema5bb, Drer\si:ch211-113g11.6, Drer\sema5ba, Drer\sema4gb, Drer\sema4bb, Drer\sema4ab, Drer\sema4d, Drer\rttn, Drer\sema6dl, Drer\sema3bl, Drer\sema3gb, Drer\sema3aa, Drer\sema6bb, Drer\sema5a, Drer\LOC798168, Drer\sema7a, Drer\sema3ab, Drer\sema3b, Drer\sema3h, Drer\sema3ga, Drer\si:ch211-129c21.1" - "Cele\smp-1, Cele\C36B7.5, Cele\mab-20" "Xtro\sema6a, Xtro\sema4c, Xtro\sema5b, Xtro\sema4d, Xtro\sema3b, Xtro\sema4g, Xtro\sema3d, Xtro\sema3c, Xtro\sema4b, Xtro\sema6d, Xtro\sema6b, Xtro\sema3a, Xtro\sema3f, Xtro\sema4a" "Mmus\Sema4g, Mmus\Sema6a, Mmus\Sema4d, Mmus\Sema3c, Mmus\Sspo, Mmus\Sema3b, Mmus\Sema6b, Mmus\Sema4b, Mmus\Sema6c, Mmus\Sema3d, Mmus\Sema4c, Mmus\Sema3e, Mmus\Sema4f, Mmus\Sema4a, Mmus\Sema5b, Mmus\Sema7a, Mmus\Sema3a, Mmus\Sema3f, Mmus\Sema6d, Mmus\Sema5a, Mmus\Sema3g" "Hsap\SEMA4C, Hsap\SEMA3E, Hsap\SEMA4F, Hsap\SEMA3B, Hsap\SEMA7A, Hsap\SEMA3F, Hsap\SEMA3A, Hsap\SEMA6C, Hsap\SEMA6B, Hsap\SEMA4A, Hsap\SEMA3D, Hsap\SEMA3G, Hsap\SEMA4B, Hsap\SEMA5B, Hsap\SEMA3C, Hsap\SEMA4G, Hsap\SEMA4D, Hsap\SEMA5A, Hsap\SEMA6D, Hsap\SEMA6A" FBgn0042167 CG18847 - http://flybase.org/reports/FBgn0042167 protein_coding_gene - - - CG18847 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038876 CG5919 - http://flybase.org/reports/FBgn0038876 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797 isopentenyl-diphosphate delta-isomerase activity ; GO:0004452 | inferred from sequence or structural similarity with HGNC:5387 isopentenyl-diphosphate delta-isomerase activity ; GO:0004452 | inferred from biological aspect of ancestor with PANTHER:PTN000094419" isoprenoid biosynthetic process ; GO:0008299 | inferred from sequence or structural similarity with HGNC:5387 isopentenyl diphosphate biosynthetic process ; GO:0009240 | inferred from biological aspect of ancestor with PANTHER:PTN000094419 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:5387 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000094419 "CG5919, IPPI" "IPR000086:NUDIX hydrolase domain, IPR011876:Isopentenyl-diphosphate delta-isomerase, type 1, IPR015797:NUDIX hydrolase domain-like" CG5919 11-Aug-17 DroID_v2017_08 Drer\idi1 Scer\IDI1 Cele\idi-1 Xtro\idi1 "Mmus\Idi1, Mmus\Gm38481, Mmus\Idi2" "Hsap\IDI2, Hsap\IDI1" "viable,visible" tormogen cell FBgn0026874 CG13358 - http://flybase.org/reports/FBgn0026874 - protein_coding_gene - - - "CG13358, EG:34F3.10" - CG13358 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052857 CG32857 - http://flybase.org/reports/FBgn0052857 protein_coding_gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR001075 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001075 molecular_function ; GO:0003674 | no biological data available "iron-sulfur cluster assembly ; GO:0016226 | inferred from electronic annotation with InterPro:IPR001075, InterPro:IPR017065 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available CG32857 "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR014824:Scaffold protein Nfu/NifU, N-terminal, IPR001075:NIF system FeS cluster assembly, NifU, C-terminal, IPR017065:NFU1 iron-sulfur cluster scaffold homologue" CG32857 11-Aug-17 DroID_v2017_08 "Drer\zgc:110319, Drer\nfu1" Scer\NFU1 Cele\lpd-8 Xtro\nfu1 Mmus\Nfu1 Hsap\NFU1 FBgn0085512 RYa RYamide http://flybase.org/reports/FBgn0085512 protein_coding_gene receptor agonist activity ; GO:0048018 | inferred from physical interaction with RYa-R cell surface receptor signaling pathway ; GO:0007166 | inferred from direct assay negative regulation of feeding behavior ; GO:2000252 | inferred from direct assay "extracellular space ; GO:0005615 | inferred by curator from GO:0007166,GO:0048018 extracellular region ; GO:0005576 | inferred by curator from GO:0007166,GO:0048018" "CG40733, dRYamide, RYa, RYamide" - CG40733 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025824 HelIII HelIII http://flybase.org/reports/FBgn0025824 - gene helicase activity ; GO:0004386 | inferred from direct assay - - "DHEL III, HelIII" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000270 ccd central complex deranged http://flybase.org/reports/FBgn0000270 - gene - - - ccd - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,recessive,memory defective,locomotor behavior defective" ellipsoid body FBgn0000939 fs(2)A9 female sterile (2) A9 http://flybase.org/reports/FBgn0000939 - gene - - - fs(2)A9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "female reproductive system,egg,chorion,nucleus | pre-blastoderm stage" FBgn0005388 fs(1)A457 female sterile (1) A457 http://flybase.org/reports/FBgn0005388 "FBgn0000757, FBgn0000772" gene - - - "fs(1)457, fs(1)M22, fs(1)A457" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,non-rescuable maternal effect,maternal effect,mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,rescuable maternal effect" "gastrula embryo,blastoderm embryo,rescuable maternal effect,egg,maternal effect" FBgn0039124 tbrd-1 testis-specifically expressed bromodomain containing protein-1 http://flybase.org/reports/FBgn0039124 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay "spermatogenesis ; GO:0007283 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 spermatid differentiation ; GO:0048515 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay nuclear body ; GO:0016604 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "tbrd-1, CG13597, tBRD-1" "IPR001487:Bromodomain, IPR018359:Bromodomain, conserved site" CG13597 11-Aug-17 DroID_v2017_08 "Drer\brd3a, Drer\brdt, Drer\brd3b, Drer\brd4, Drer\brd2b, Drer\brd2a" "Scer\BDF2, Scer\SPT7, Scer\BDF1" "Cele\bet-1, Cele\baz-2, Cele\bet-2, Cele\F59F5.7" "Xtro\brd2, Xtro\brdt, Xtro\pbrm1, Xtro\brd3, Xtro\brd4" "Mmus\Brd2, Mmus\Baz1a, Mmus\Brd3, Mmus\Brdt, Mmus\Brd4, Mmus\Cecr2" "Hsap\BRDT, Hsap\BRD2, Hsap\BAZ1A, Hsap\BRD4, Hsap\BRD3, Hsap\CCDC127, Hsap\CECR2" "male sterile,male fertile,viable" "spermatid,Nebenkern,sperm individualization complex" FBgn0031664 CG8892 - http://flybase.org/reports/FBgn0031664 protein_coding_gene - - - CG8892 "IPR001012:UBX domain, IPR006577:UAS, IPR009060:UBA-like, IPR017346:UBX domain-containing protein 2/7, IPR012336:Thioredoxin-like fold, IPR029071:Ubiquitin-related domain" CG8892 11-Aug-17 DroID_v2017_08 Drer\ubxn7 Scer\UBX5 "Cele\C16C8.9, Cele\T05E12.6, Cele\ZK1037.6" Xtro\ubxn7 Mmus\Ubxn7 Hsap\UBXN7 viable FBgn0034903 sona sol narae http://flybase.org/reports/FBgn0034903 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001590 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001590 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype inferred from genetic interaction with wg imaginal disc-derived appendage development ; GO:0048737 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from direct assay Golgi-associated vesicle ; GO:0005798 | inferred from direct assay "dimp, Dimp, CG11169, CG9850, sona" "IPR001590:Peptidase M12B, ADAM/reprolysin, IPR024079:Metallopeptidase, catalytic domain, IPR034030:Salivary gland reprolysin domain, IPR011990:Tetratricopeptide-like helical domain" CG9850 11-Aug-17 DroID_v2017_08 "Drer\adamts15a, Drer\LOC100002059, Drer\adamtsl5, Drer\adamts18, Drer\adamtsl3, Drer\adamts8a, Drer\thsd7bb, Drer\adamts13, Drer\adamts12, Drer\adamts6, Drer\adamts2, Drer\adamts7, Drer\adamts1, Drer\adamtsl2, Drer\LOC568792" - Cele\mig-17 "Xtro\adamts18, Xtro\adamts7, Xtro\adamts15, Xtro\adamts16, Xtro\adamts20, Xtro\adamts12, Xtro\adamts6, Xtro\adamts9" "Mmus\Adamts6, Mmus\Adamts13, Mmus\Adamts20, Mmus\Adamts8, Mmus\Thsd7a, Mmus\Adamts1, Mmus\Adamts12, Mmus\Adamts9, Mmus\Adamts4, Mmus\Adamts16, Mmus\Adamts7, Mmus\Thsd4, Mmus\Adamts18, Mmus\Adamtsl4, Mmus\Adamtsl1, Mmus\Sspo, Mmus\Adamts10, Mmus\Adamtsl5, Mmus\Adamts19, Mmus\Adamts5, Mmus\Adamts15, Mmus\Adamts14" "Hsap\ADAMTSL1, Hsap\ADAMTS7, Hsap\ADAMTS16, Hsap\ADAMTSL5, Hsap\ADAMTS19, Hsap\ADAMTS6, Hsap\ADAMTS8, Hsap\ADAMTS12, Hsap\ADAMTS13, Hsap\THSD4, Hsap\ADAMTS15, Hsap\ADAMDEC1, Hsap\ADAMTS18, Hsap\ADAMTS10, Hsap\ADAM17, Hsap\ADAMTSL4, Hsap\ADAMTS20, Hsap\ADAMTS9, Hsap\THSD7B, Hsap\ADAMTS4, Hsap\ADAMTS5, Hsap\ADAMTS17, Hsap\ADAMTS14, Hsap\ADAMTS1" "viable,fertile" DRSC04089 E -0.253965377 0.560930084 1.780878089 0.499976519 -0.495817229 0.746732139 FBgn0050355 CG30355 - http://flybase.org/reports/FBgn0050355 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs23a07, NEST:bs23e07, NEST:bs06e10, NEST:bs04f07, BcDNA:AT24812, NEST:bs10b08, CG30355" - CG30355 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0021785 l(3)02670 lethal (3) 02670 http://flybase.org/reports/FBgn0021785 - gene - - - "l(2)02670, l(3)02670" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263599 l(3)72Ab lethal (3) 72Ab http://flybase.org/reports/FBgn0263599 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000000974 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from sequence or structural similarity ventral cord development ; GO:0007419 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with UniProtKB:O75643" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleus ; GO:0005634 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from physical interaction with Prp8 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with UniProtKB:O75643 "brr2, CG5931, l(3)72Ab, ASCC3L1, Brr2, cg5931, clone 1.21, anon-EST:Liang-1.21" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR001650:Helicase, C-terminal, IPR004179:Sec63 domain, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014756:Immunoglobulin E-set, IPR000008:C2 domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5931 11-Aug-17 DroID_v2017_08 "Drer\ascc3, Drer\snrnp200, Drer\hfm1" "Scer\HFM1, Scer\SLH1, Scer\BRR2" "Cele\dnj-29, Cele\Y54E2A.4, Cele\snrp-200" Xtro\snrnp200 "Mmus\Snrnp200, Mmus\Ascc3, Mmus\Hfm1" "Hsap\HFM1, Hsap\SNRNP200, Hsap\ASCC3" DRSC10559 IE -0.824683325 2.703476299 -2.048692294 -0.893859185 -1.160825837 -0.489464655 FBgn0034345 CG5174 - http://flybase.org/reports/FBgn0034345 protein_coding_gene - - - "BcDNA:RH27395, BcDNA:RE18604, CG5174" IPR007327:Tumour protein D52 CG5174 11-Aug-17 DroID_v2017_08 "Drer\tpd52l2b, Drer\tpd52l2a, Drer\tpd52, Drer\tpd52l1" - Cele\F13E6.1 "Xtro\tpd52, Xtro\tpd52l1" "Mmus\Trpd52l3, Mmus\Tpd52l2, Mmus\Tpd52, Mmus\Tpd52l1" "Hsap\TPD52L3, Hsap\TPD52L2, Hsap\TPD52, Hsap\TPD52L1" "viable,fertile" FBgn0020819 l(3)98Dk lethal (3) 98Dk http://flybase.org/reports/FBgn0020819 - gene - - - "M31, l(3)98Dk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069408 JJF178 JJF178 http://flybase.org/reports/FBgn0069408 gene - - - JJF178 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0060687 l(3)S074913 lethal (3) S074913 http://flybase.org/reports/FBgn0060687 gene - - - "0749/13, l(3)S074913" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013610 l(3)E8-3-54 lethal (3) E8-3-54 http://flybase.org/reports/FBgn0013610 - gene - - - l(3)E8-3-54 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264549 CR43928 - http://flybase.org/reports/FBgn0264549 non_protein_coding_gene - - - CR43928 - CR43928 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060751 l(3)S064912 lethal (3) S064912 http://flybase.org/reports/FBgn0060751 gene - - - "0649/12, l(3)S064912" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0036279 Ncc69 sodium chloride cotransporter 69 http://flybase.org/reports/FBgn0036279 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 sodium:potassium:chloride symporter activity ; GO:0008511 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 potassium ion transport ; GO:0006813 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from direct assay rubidium ion transport ; GO:0035826 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004842 plasma membrane ; GO:0005886 | inferred from direct assay "CG4357, CG43567, CK01027, NCC69, BEST:CK01027, Ncc69, mdcds_25302" "IPR002443:Na/K/Cl co-transporter, IPR004841:Amino acid permease/ SLC12A domain, IPR004842:SLC12A transporter family, IPR018491:SLC12A transporter, C-terminal" CG4357 11-Aug-17 DroID_v2017_08 "Drer\slc12a10.3, Drer\slc12a10.1, Drer\slc12a2, Drer\slc12a10.2, Drer\slc12a8, Drer\slc12a1, Drer\slc12a3" Scer\VHC1 "Cele\nkcc-1, Cele\B0303.11" "Xtro\slc12a2, Xtro\slc12a3, Xtro\slc12a1" "Mmus\Slc12a2, Mmus\Slc12a3, Mmus\Slc12a1, Mmus\Slc12a8" "Hsap\SLC12A1, Hsap\SLC12A8, Hsap\SLC12A2, Hsap\SLC12A3" "viable,neuroanatomy defective,fertile,bang sensitive,paralytic" "abdominal nerve,abdominal nerve | third instar larval stage" DRSC10413 I 1.940446653 1.702325733 0.728097408 1.081331537 -0.191863888 -0.223638111 FBgn0051053 CG31053 - http://flybase.org/reports/FBgn0051053 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model SUMO transferase activity ; GO:0019789 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 synapsis ; GO:0007129 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 protein sumoylation ; GO:0016925 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 synaptonemal complex ; GO:0000795 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 CG31053 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31053 11-Aug-17 DroID_v2017_08 - Scer\CST9 "Cele\D1081.9, Cele\zhp-3, Cele\F55A12.10, Cele\R06C7.2, Cele\Y39B6A.16" - "Mmus\Rnf212b, Mmus\Rnf212" "Hsap\RNF212B, Hsap\RNF212" viable FBgn0069942 CG41101 - http://flybase.org/reports/FBgn0069942 protein_coding_gene - - - CG41101 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015782 Pa Puffrmel http://flybase.org/reports/FBgn0015782 - gene - - - Pa - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" wing FBgn0017444 anon-15Dc anon-15Dc http://flybase.org/reports/FBgn0017444 - gene - - - anon-15Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004035 yea1 yeast 1 http://flybase.org/reports/FBgn0004035 - gene - - - yea1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002142 l(2)K327 lethal (2) K327 http://flybase.org/reports/FBgn0002142 - gene - - - l(2)K327 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002769 mit(1)21 mitotic 21 http://flybase.org/reports/FBgn0002769 - gene - - - mit(1)21 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267322 CR45758 - http://flybase.org/reports/FBgn0267322 non_protein_coding_gene - - - CR45758 - CR45758 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265853 CR44642 - http://flybase.org/reports/FBgn0265853 non_protein_coding_gene - - - CR44642 - CR44642 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022153 l(2)k05819 lethal (2) k05819 http://flybase.org/reports/FBgn0022153 FBgn0044723 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR023299 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3054, anon-WO0140519.156, l(2)k05819" "IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N, IPR023298:P-type ATPase, transmembrane domain" CG3054 11-Aug-17 DroID_v2017_08 Drer\tmem94 - Cele\D1007.15 Xtro\tmem94 Mmus\Tmem94 Hsap\TMEM94 "lethal,recessive,viable,fertile" FBgn0032373 Vha100-5 Vacuolar H[+] ATPase 100kD subunit 5 http://flybase.org/reports/FBgn0032373 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000005796 ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000179505" vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence or structural similarity with SGD:S000005796 vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 "vacuolar proton-transporting V-type ATPase complex ; GO:0016471 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000907964 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000005796" "CG12602, Vha100-5, vha100-5" "IPR002490:V-type ATPase, V0 complex, 116kDa subunit family, IPR026028:ATPase, V0 complex, subunit 116kDa, eukaryotic" CG12602 11-Aug-17 DroID_v2017_08 "Drer\tcirg1b, Drer\si:ch73-173p19.2, Drer\atp6v0a2a, Drer\atp6v0a1a, Drer\atp6v0a1b, Drer\tcirg1a, Drer\atp6v0a2b" "Scer\STV1, Scer\VPH1" "Cele\vha-7, Cele\unc-32, Cele\vha-6, Cele\vha-5" "Xtro\atp6v0a4, Xtro\tcirg1, Xtro\atp6v0a1, Xtro\atp6v0a2" "Mmus\Atp6v0a4, Mmus\Tcirg1, Mmus\Atp6v0a2, Mmus\Atp6v0a1" "Hsap\ATP6V0A2, Hsap\ATP6V0A1, Hsap\ATP6V0A4, Hsap\TCIRG1" "visible,viable" wing DRSC02175 IEK 1.635735752 -1.118750573 -1.286887755 -2.065949073 1.529998519 0.080140718 FBgn0082939 snoRNA:Me28S-C3227b snoRNA:Me28S-C3227b http://flybase.org/reports/FBgn0082939 snoRNA_gene - - - "snoRNA:Me28S-C3227b, Me28S-Cm3227b, CR34534" - CR34534 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010470 Fkbp14 FK506-binding protein 14 http://flybase.org/reports/FBgn0010470 "FBgn0027068, FBgn0064945" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 FK506 binding ; GO:0005528 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 FK506 binding ; GO:0005528 | inferred from sequence or structural similarity peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from sequence or structural similarity peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 chaeta development ; GO:0022416 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with Dl inferred from genetic interaction with Psn imaginal disc development ; GO:0007444 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 endomembrane system ; GO:0012505 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "FKB13, BcDNA.GM07659, l(2)00734, GM07659, CG9847, BcDNA:GM07659, BcDNA:GH08925, Fkbp13, FKBP13, fkbp13, Fkbp14, FKBP14" "IPR018247:EF-Hand 1, calcium-binding site, IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR002048:EF-hand domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR011992:EF-hand domain pair" CG9847 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-208h16.4, Drer\fkbp14, Drer\fkbp1ab, Drer\fkbp10a, Drer\fkbp11, Drer\fkbp7, Drer\fkbp2, Drer\fkbp10b, Drer\fkbp1aa, Drer\fkbp1b, Drer\si:ch73-199g24.2, Drer\fkbp9" Scer\FPR2 "Cele\fkb-2, Cele\fkb-3, Cele\fkb-5, Cele\fkb-4, Cele\fkb-7, Cele\fkb-1" "Xtro\fkbp9, Xtro\fkbp15, Xtro\fkbp7, Xtro\fkbp1b, Xtro\fkbp10, Xtro\fkbp14, Xtro\fkbp3" "Mmus\Fkbp3, Mmus\Fkbp9, Mmus\Fkbp2, Mmus\Fkbp1b, Mmus\Fkbp15, Mmus\Fkbp1a, Mmus\Fkbp14, Mmus\Fkbp10, Mmus\Fkbp11, Mmus\Fkbp7" "Hsap\FKBP14, Hsap\FKBP11, Hsap\FKBP2, Hsap\FKBP1B, Hsap\FKBP10, Hsap\FKBP7, Hsap\FKBP5, Hsap\FKBP15, Hsap\FKBP9, Hsap\FKBP3" "lethal - all die before end of P-stage,lethal,female sterile,germline clone,cell lethal,somatic clone,viable,behavior defective,recessive,long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective,fertile,neuroanatomy defective" "mesothoracic bristle,notal microchaeta,wing margin,wing margin bristle,sensory mother cell,wing disc,imaginal disc,synapse" FBgn0263769 CR43686 - http://flybase.org/reports/FBgn0263769 non_protein_coding_gene - - - CR43686 - CR43686 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021985 l(2)k09837 lethal (2) k09837 http://flybase.org/reports/FBgn0021985 - gene - - - l(2)k09837 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025797 Su(var)401 Suppressor of variegation 401 http://flybase.org/reports/FBgn0025797 - gene - - - "Su-var(2)401, Su(var)401" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082945 snoRNA:Me28S-A2634b snoRNA:Me28S-A2634b http://flybase.org/reports/FBgn0082945 snoRNA_gene - - - "snoRNA:Me28S-A2634b, Me28S-Am2634b, CR34635, Me28S-A2634b" - CR34635 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266114 CR44840 - http://flybase.org/reports/FBgn0266114 non_protein_coding_gene - - - CR44840 - CR44840 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033294 Mal-A4 Maltase A4 http://flybase.org/reports/FBgn0033294 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "Mal-A4, mal_A4, CG8693, Drome_A4" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG8693 11-Aug-17 DroID_v2017_08 "Drer\slc3a2a, Drer\zgc:158423, Drer\si:dkey-202g17.3, Drer\slc3a2b, Drer\slc3a1" "Scer\IMA4, Scer\IMA1, Scer\IMA5, Scer\IMA2, Scer\MAL12, Scer\IMA3, Scer\MAL32" "Cele\atgp-2, Cele\atgp-1" "Xtro\slc3a2, Xtro\slc3a1" "Mmus\Slc3a2, Mmus\Slc3a1" "Hsap\SLC3A1, Hsap\SLC3A2" viable DRSC07236 K -0.625453206 -0.343737192 0.532224439 -0.705245538 -0.502000565 1.876948051 FBgn0045840 lambdaDsubFC4 lambdaDsubFC4 http://flybase.org/reports/FBgn0045840 gene - - - lambdaDsubFC4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040987 CG15139 - http://flybase.org/reports/FBgn0040987 protein_coding_gene - - - CG15139 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045465 HP1c::Su(var)205 HP1c::Su(var)205 http://flybase.org/reports/FBgn0045465 engineered_fusion_gene - - - HP1c::Su(var)205 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086077 snoRNA:Me18S-G962 - http://flybase.org/reports/FBgn0086077 snoRNA_gene - - - "snoRNA:Me18S-G962, Me18S-Gm962, CR34706" - CR34706 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033402 Myd88 Myd88 http://flybase.org/reports/FBgn0033402 protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with wek Toll binding ; GO:0005121 | inferred from physical interaction with Tl protein binding ; GO:0005515 | inferred from physical interaction with Fadd phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from mutant phenotype" innate immune response ; GO:0045087 | non-traceable author statement dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement Toll signaling pathway ; GO:0008063 | inferred from genetic interaction with tub inferred from genetic interaction with pll defense response to fungus ; GO:0050832 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype positive regulation of antifungal peptide production ; GO:0002804 | inferred from direct assay response to fungus ; GO:0009620 | traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement antifungal peptide production ; GO:0002781 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "dMyd88, Kra, MyD88, dMyD88, kra, DMMYD88, DmMyD88, CG2078, LD20892, EP(2)2535, DmMyd88, Myd88, myd88, MYD88, Myd88F, dMYd88" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR011029:Death-like domain" CG2078 11-Aug-17 DroID_v2017_08 Drer\myd88 - - Xtro\myd88 Mmus\Myd88 "Hsap\TIRAP, Hsap\MYD88, Hsap\SIGIRR" "immune response defective,recessive,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female fertile,viable,lethal,dorsal/ventral axis specification defective,germline clone,non-rescuable maternal effect" "filzkorper,denticle belt,embryonic epidermis,ventral" FBgn0024993 CG2662 - http://flybase.org/reports/FBgn0024993 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 - - "EG:100G10.6, CG2662, snuts, MAD" "IPR001660:Sterile alpha motif domain, IPR001965:Zinc finger, PHD-type, IPR013761:Sterile alpha motif/pointed domain, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR011011:Zinc finger, FYVE/PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2662 11-Aug-17 DroID_v2017_08 "Drer\samd1a, Drer\samd1b, Drer\samd13" Scer\SFP1 "Cele\mys-4, Cele\dpff-1" Xtro\samd13 "Mmus\4930503B20Rik, Mmus\Samd1, Mmus\Dpf2" "Hsap\SAMD13, Hsap\SAMD1, Hsap\DPF2, Hsap\THAP10" viable DRSC18468 IK 2.18349238 1.75573769 1.082161342 0.172355973 1.689209517 0.294458768 FBgn0267154 CR45594 - http://flybase.org/reports/FBgn0267154 non_protein_coding_gene - - - CR45594 - CR45594 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037429 Osi19 Osiris 19 http://flybase.org/reports/FBgn0037429 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi19, CG15189" IPR012464:Protein of unknown function DUF1676 CG15189 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029161 slmo slowmo http://flybase.org/reports/FBgn0029161 protein_coding_gene - germarium-derived oocyte differentiation ; GO:0030706 | inferred from mutant phenotype peristalsis ; GO:0030432 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from mutant phenotype "CT26166, kisir, CG9131, slmo" IPR006797:PRELI/MSF1 domain CG9131 11-Aug-17 DroID_v2017_08 "Drer\prelid3b, Drer\prelid3a" "Scer\UPS3, Scer\UPS2" Cele\F15D3.6 "Xtro\prelid3a, Xtro\prelid2" "Mmus\Prelid2, Mmus\Slmo1, Mmus\Slmo2" "Hsap\PRELID3A, Hsap\PRELID3B, Hsap\PRELID2" "viable,male sterile,recessive,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,lethal,flight defective,visible" "wing,trichogen cell,mesothoracic tergum" DRSC03143 IEK -1.518622585 -1.072497697 -0.957496416 -2.747169355 1.595478521 0.490373303 FBgn0033154 CG1850 - http://flybase.org/reports/FBgn0033154 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG1850 - CG1850 11-Aug-17 DroID_v2017_08 "Drer\zgc:162964, Drer\acbd3, Drer\tmed8" - Cele\Y41E3.7 - "Mmus\Tmed8, Mmus\Acbd3" "Hsap\TMED8, Hsap\ACBD3" viable FBgn0010062 M(2)34d M(2)34d http://flybase.org/reports/FBgn0010062 - gene - - - M(2)34d - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0065512 l(2)SH1166 lethal (2) SH1166 http://flybase.org/reports/FBgn0065512 gene - - - l(2)SH1166 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005038 Est-A Esterase A http://flybase.org/reports/FBgn0005038 - gene - - - "Est18, Est-A" - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0085762 CG40648 - http://flybase.org/reports/FBgn0085762 protein_coding_gene - - - "CG40648, CR40648" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267875 CR46163 - http://flybase.org/reports/FBgn0267875 pseudogene_attribute - - - CR46163 - CR46163 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031947 CG7154 - http://flybase.org/reports/FBgn0031947 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - "CG7154, BRD7" "IPR001487:Bromodomain, IPR021900:Protein of unknown function DUF3512" CG7154 11-Aug-17 DroID_v2017_08 "Drer\brd9, Drer\brd7" - Cele\swsn-9 "Xtro\brd9, Xtro\brd7" "Mmus\Brd9, Mmus\Brd7" "Hsap\BRD9, Hsap\BRD7" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC03017 E -0.697418664 0.719613499 0.226420442 -1.509175214 -0.521056247 1.062154707 FBgn0030718 ND-20 NADH dehydrogenase (ubiquinone) 20 kDa subunit http://flybase.org/reports/FBgn0030718 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR006138 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR006138 quinone binding ; GO:0048038 | inferred from electronic annotation with InterPro:IPR006138 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O75251" "mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O75251 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype response to reactive oxygen species ; GO:0000302 | inferred from mutant phenotype" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O75251 "CG9172, 20 kDa, NUKM, ND-20, Dmel_CG9172, PSST" "IPR006137:NADH:ubiquinone oxidoreductase-like, 20kDa subunit, IPR006138:NADH-ubiquinone oxidoreductase, 20 Kd subunit" CG9172 11-Aug-17 DroID_v2017_08 Drer\ndufs7 - Cele\nduf-7 Xtro\ndufs7 Mmus\Ndufs7 Hsap\NDUFS7 "lethal - all die before end of larval stage,some die during larval stage,long lived,female,RU486 conditional,female semi-fertile,stress response defective,viable,visible" "trichogen cell,mesothoracic tergum,adult heart,RU486 conditional" FBgn0020280 laf labial associated factor http://flybase.org/reports/FBgn0020280 "FBgn0015605, FBgn0037285" protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - "C6, CG14660, laf" - CG14660 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001847 l(1)ts3803 lethal (1) ts3803 http://flybase.org/reports/FBgn0001847 - gene - - - l(1)ts3803 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0045053 fs(1)221a female sterile (1) 221a http://flybase.org/reports/FBgn0045053 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)221a - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "nurse cell & nucleus,nurse cell,follicle cell,border follicle cell" FBgn0260756 CG42554 - http://flybase.org/reports/FBgn0260756 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG13886, CT33419, CG42554" - CG42554 11-Aug-17 DroID_v2017_08 "Drer\nrbf2b, Drer\nrbf2a, Drer\zgc:55781" - - Xtro\c7orf25 "Mmus\AW209491, Mmus\Nrbf2" "Hsap\C7orf25, Hsap\NRBF2" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,mesothoracic tergum" FBgn0004991 chy chunky http://flybase.org/reports/FBgn0004991 - gene - - - chy - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,adult abdomen" FBgn0010930 l(3)08724 lethal (3) 08724 http://flybase.org/reports/FBgn0010930 - gene - - - l(3)08724 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083080 luke lucky luke http://flybase.org/reports/FBgn0083080 gene - - - luke - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069958 CG41059 - http://flybase.org/reports/FBgn0069958 protein_coding_gene - - - CG41059 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051820 CG31820 - http://flybase.org/reports/FBgn0051820 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs36g10, NEST:bs10d03, CG31820" - CG31820 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004032 wz wizened http://flybase.org/reports/FBgn0004032 - gene - - - wz - - 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,recessive,visible,body color defective" macrochaeta FBgn0044040 Masc29a Masc29a http://flybase.org/reports/FBgn0044040 gene - - - Masc29a - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051862 CG31862 - http://flybase.org/reports/FBgn0051862 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31862 - CG31862 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053648 CG33648 - http://flybase.org/reports/FBgn0053648 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33648 IPR010512:Protein of unknown function DUF1091 CG33648 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263331 CR43412 - http://flybase.org/reports/FBgn0263331 non_protein_coding_gene - - - CR43412 - CR43412 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086611 Lcp65Ag3 Larval cuticle protein http://flybase.org/reports/FBgn0086611 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Lcp65Ag3, Lcp-g3, g3, CG18779, DmelLcp65Ag3" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG18779 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " larval stage , embryonic stage , pupal stage | 7-13 hr " FBgn0030815 CG8945 - http://flybase.org/reports/FBgn0030815 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "CG8945, Cg8945" "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG8945 11-Aug-17 DroID_v2017_08 "Drer\aebp1, Drer\cpa6, Drer\si:ch1073-459j12.1, Drer\cpa2, Drer\cpo, Drer\cpb1, Drer\cpa1, Drer\cpb2, Drer\cpa5, Drer\cpa4" Scer\ECM14 "Cele\F02D8.4, Cele\Y59C2A.1" "Xtro\cpa3, Xtro\cpo, Xtro\cpb1, Xtro\cpb2, Xtro\cpa1" "Mmus\Cpa6, Mmus\Cpb2, Mmus\Cpa2, Mmus\Cpa1, Mmus\Cpa4, Mmus\Cpb1, Mmus\Cpa5, Mmus\Cpa3, Mmus\Cpn1" "Hsap\CPA2, Hsap\CPA3, Hsap\CPA1, Hsap\CPO, Hsap\CPA5, Hsap\CPA4, Hsap\CPNE1, Hsap\CPA6, Hsap\CPB1, Hsap\CPB2" "viable,fertile" FBgn0038046 CG5641 - http://flybase.org/reports/FBgn0038046 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006116 transferase activity ; GO:0016740 | inferred from electronic annotation with InterPro:IPR006116 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q12905 double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity with UniProtKB:Q12905 "immune response ; GO:0006955 | inferred from electronic annotation with InterPro:IPR006116 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:Q12905 transcription, DNA-templated ; GO:0006351 | inferred from sequence or structural similarity with UniProtKB:Q12905 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q12905 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q12905 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG5641 "IPR006116:2-5-oligoadenylate synthetase, N-terminal, IPR006561:DZF domain" CG5641 11-Aug-17 DroID_v2017_08 Drer\ilf2 Scer\TAD1 "Cele\R11H6.5, Cele\Y95B8A.8" Xtro\ilf2 Mmus\Ilf2 Hsap\ILF2 viable DRSC15852 E 0.126167555 -0.339090084 -1.603873037 0.347652821 -0.241072059 -0.20936792 FBgn0032421 crok crooked http://flybase.org/reports/FBgn0032421 protein_coding_gene - "regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay "BcDNA:RE65321, CG17218, crok" - CG17218 11-Aug-17 DroID_v2017_08 - - "Cele\K11H12.6, Cele\K11H12.7, Cele\C15H9.9, Cele\F35C5.11" - - - "lethal,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval dorsal trunk,presumptive embryonic salivary gland,embryonic/larval tracheal system,septate junction" FBgn0002821 ms(2)11R male sterile (2) 11R http://flybase.org/reports/FBgn0002821 - gene - - - ms(2)11R - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0034217 Lhr Lethal hybrid rescue http://flybase.org/reports/FBgn0034217 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 protein binding ; GO:0005515 | inferred from physical interaction with Hmr negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype regulation of transposition ; GO:0010528 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype "chromocenter ; GO:0010369 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay" "CG18468, Lhr, mel-Lhr, HP3, LHR, LHR[[mel]]" IPR004210:BESS motif CG18468 11-Aug-17 DroID_v2017_08 - - - - - - "female semi-sterile,recessive,progressive,viable" FBgn0001784 l(1)M82 lethal (1) M82 http://flybase.org/reports/FBgn0001784 - gene - - - l(1)M82 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" macrochaeta FBgn0263869 CR43716 - http://flybase.org/reports/FBgn0263869 non_protein_coding_gene - - - CR43716 - CR43716 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030317 CG1561 - http://flybase.org/reports/FBgn0030317 protein_coding_gene - - - "e, CG1561" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG1561 11-Aug-17 DroID_v2017_08 - - "Cele\dhs-27, Cele\H06H21.8, Cele\nhr-246, Cele\F59B1.8, Cele\C29F7.2" - - - partially lethal - majority die FBgn0065373 l(2)SH1692 lethal (2) SH1692 http://flybase.org/reports/FBgn0065373 gene - - - "l(2)SH1692, l(2)SH2 1692" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001341 l(1)1Bi lethal (1) 1Bi http://flybase.org/reports/FBgn0001341 - protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007015 DNA-directed DNA polymerase activity ; GO:0003887 | inferred from electronic annotation with InterPro:IPR007015 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR007015" - "l(1)lBi, EG:115C2.2, CG6189, l(1)Bi, HM-52, HM-419, l(1)1Bi" "IPR007015:DNA polymerase V, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG6189 11-Aug-17 DroID_v2017_08 Drer\mybbp1a Scer\POL5 Cele\K04C2.2 - Mmus\Mybbp1a Hsap\MYBBP1A " adult stage , embryonic stage " "wild-type,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,visible,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" macrochaeta FBgn0261679 CG42726 - http://flybase.org/reports/FBgn0261679 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG12258, CG31392, CG42726" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG42726 11-Aug-17 DroID_v2017_08 Drer\zgc:162971 Scer\AZF1 "Cele\C27A2.7, Cele\slr-2" Xtro\LOC100496354 - "Hsap\ZNF44, Hsap\ZNF679" viable FBgn0000761 fs(1)A476 female sterile (1) A476 http://flybase.org/reports/FBgn0000761 - gene - - - fs(1)A476 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0262544 CG43098 - http://flybase.org/reports/FBgn0262544 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43098, chr3L_3658997_3659727.0" - CG43098 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014077 anon-10Ba anon-10Ba http://flybase.org/reports/FBgn0014077 - gene - - - "anon-10B, anon-10Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060759 l(3)S063602 lethal (3) S063602 http://flybase.org/reports/FBgn0060759 gene - - - "0636/02, l(3)S063602" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0260817 gkt glaikit http://flybase.org/reports/FBgn0260817 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 3'-tyrosyl-DNA phosphodiesterase activity ; GO:0017005 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 3'-tyrosyl-DNA phosphodiesterase activity ; GO:0017005 | inferred from sequence or structural similarity with UniProtKB:P38319 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 double-strand break repair ; GO:0006302 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 single strand break repair ; GO:0000012 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with UniProtKB:P38319 central nervous system development ; GO:0007417 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P38319 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 "gkt, c22, Tdp1, CG8826, CG8825, anon-23Db, Gkt, TDP1" "IPR010347:Tyrosyl-DNA phosphodiesterase I, IPR019406:Zinc finger, C2H2, APLF-like, IPR027415:Tyrosyl-DNA phosphodiesterase C-terminal domain" CG8825 11-Aug-17 DroID_v2017_08 Drer\tdp1 Scer\TDP1 Cele\F52C12.1 Xtro\tdp1 Mmus\Tdp1 Hsap\TDP1 FBgn0017602 Hrb3 Hrb3 http://flybase.org/reports/FBgn0017602 - gene - - - Hrb3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265678 CR44485 - http://flybase.org/reports/FBgn0265678 non_protein_coding_gene - - - CR44485 - CR44485 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051939 tRNA:Gln-CTG-2-4 transfer RNA:Glutamine-CTG 2-4 http://flybase.org/reports/FBgn0051939 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002638.trna6-GlnCTG, tRNA:Q:CTG:AE002638-c, CR31939, chr2L.trna39-GlnCTG, tRNA:Gln-CTG-2-4, tRNA:CR31939, tRNA-Gln-CTG-2-4, CAG" - CR31939 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261877 Z2-2626 - http://flybase.org/reports/FBgn0261877 gene - sleep ; GO:0030431 | inferred from mutant phenotype - Z2-2626 - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective FBgn0021792 l(2)k17031 lethal (2) k17031 http://flybase.org/reports/FBgn0021792 - gene - - - "l(2)k17035, l(2)k17031" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014453 17.6\pol 17.6 element transposase http://flybase.org/reports/FBgn0014453 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "17.6\T, 17.6\pol, pol" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261708 CR42745 - http://flybase.org/reports/FBgn0261708 non_protein_coding_gene - - - CR42745 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037360 CG2182 - http://flybase.org/reports/FBgn0037360 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001006389 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001006389 CG2182 IPR026073:Gametogenetin-binding protein 2 CG2182 11-Aug-17 DroID_v2017_08 Drer\ggnbp2 - - Xtro\ggnbp2 Mmus\Ggnbp2 Hsap\GGNBP2 viable FBgn0020828 l(2)SA104 lethal (2) SA104 http://flybase.org/reports/FBgn0020828 - gene - - - "l(2)SA#104, l(2)SA104" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026227 l(1)16Fn lethal (1) 16Fn http://flybase.org/reports/FBgn0026227 - gene - - - "HL-IX, l(1)16Fn" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263611 CR43620 - http://flybase.org/reports/FBgn0263611 non_protein_coding_gene - - - CR43620 - CR43620 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032981 CG3635 - http://flybase.org/reports/FBgn0032981 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - CG3635 "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG3635 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH2, Scer\YEH1, Scer\TGL1" "Cele\lipl-8, Cele\lipl-6, Cele\lipl-4, Cele\lipl-7, Cele\lipl-3, Cele\lipl-2, Cele\lipl-1, Cele\lipl-5" Xtro\lipa "Mmus\Lipo3, Mmus\Lipn, Mmus\Lipa, Mmus\Lipm, Mmus\Lipo2, Mmus\Lipo4, Mmus\Lipo1, Mmus\Lipf, Mmus\Lipk" "Hsap\LIPK, Hsap\LIPJ, Hsap\LIPA, Hsap\LIPM, Hsap\LIPN, Hsap\LIPF" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0013799 Deaf1 Deformed epidermal autoregulatory factor-1 http://flybase.org/reports/FBgn0013799 "FBtr0074882, FBpp0074651" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "regulation of immune response ; GO:0050776 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay regulation of multicellular organismal development ; GO:2000026 | inferred from biological aspect of ancestor with PANTHER:PTN000812953 embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "DEAF-1, Deaf-1, CG8567, Deaf1, DEAF1, deaf1, l(3)76BDv" "IPR000770:SAND domain, IPR002893:Zinc finger, MYND-type, IPR010919:SAND domain-like, IPR024119:Transcription factor DEAF-1" CG8567 11-Aug-17 DroID_v2017_08 "Drer\gmeb1, Drer\sp100.3, Drer\si:ch73-302a13.2, Drer\deaf1" - - "Xtro\gmeb2, Xtro\gmeb1" "Mmus\Gmeb2, Mmus\Deaf1, Mmus\Gmeb1" "Hsap\GMEB2, Hsap\DEAF1, Hsap\GMEB1" embryonic stage | early

ubiquitous " embryonic stage , embryonic stage | stage >15 " "

ubiquitous , embryonic nervous system

" "lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,partially,visible,eye color defective,viable" "embryonic segment,non-rescuable maternal effect,dorsal closure embryo,heat sensitive,extended germ band embryo,wing,wing vein L3,mesothoracic bristle,scutellar bristle,eye,ommatidium,macrochaeta" DRSC22786 E -0.997237593 -0.579331667 -3.031508297 -0.737916073 -0.49978891 0.005221521 FBgn0031266 Sf3b1 Splicing factor 3b subunit 1 http://flybase.org/reports/FBgn0031266 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000250426 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:10768 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004901 spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000250426" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000004901 U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000250426 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000250426 U2 snRNP ; GO:0005686 | colocalizes_with inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "anon-21Cd, CG2807, SF3B, Sf3b1, SF3B1" "IPR011989:Armadillo-like helical, IPR015016:Splicing factor 3B subunit 1, IPR016024:Armadillo-type fold, IPR034085:TOG domain" CG2807 11-Aug-17 DroID_v2017_08 "Drer\asxl2, Drer\sf3b1" Scer\HSH155 Cele\sftb-1 Xtro\sf3b1 Mmus\Sf3b1 Hsap\SF3B1 lethal DRSC00535 IEK -1.485029124 2.2305001 -1.800193323 -4.542704503 -5.848987187 -4.354462971 FBgn0263545 mir-4963 mir-4963 stem loop http://flybase.org/reports/FBgn0263545 miRNA_gene - - - "mir-4963, dme-mir-4963, CR43530" - CR43530 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262020 CG42831 - http://flybase.org/reports/FBgn0262020 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42831 - CG42831 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262952 mt:ND4 mitochondrial NADH-ubiquinone oxidoreductase chain 4 http://flybase.org/reports/FBgn0262952 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR003918 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from electronic annotation with InterPro:IPR000260" - "ND4, nd4, CG34085, URF4, mt:ND4, nad4, CK00534, BEST:CK00534" "IPR000260:NADH:ubiquinone oxidoreductase chain 4, N-terminal, IPR001750:NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit, IPR003918:NADH:ubiquinone oxidoreductase" CG34085 11-Aug-17 DroID_v2017_08 Drer\ND4 - Cele\ND4 Xtro\ND4 Mmus\ND4 Hsap\ND4 FBgn0016754 sba six-banded http://flybase.org/reports/FBgn0016754 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001739, InterPro:IPR016177 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN001441501" - chromocenter ; GO:0010369 | inferred from biological aspect of ancestor with PANTHER:PTN001441501 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001441501 "AAF56201, Dm Sba, CG13598, TF125, F125, Tf125, sba, DMTF125" "IPR001739:Methyl-CpG DNA binding, IPR000313:PWWP domain, IPR016177:DNA-binding domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG13598 11-Aug-17 DroID_v2017_08 Drer\mbd6 - - "Xtro\mbd6, Xtro\mbd5" "Mmus\Mbd6, Mmus\Mbd5, Mmus\Dnmt3a" "Hsap\DNMT3A, Hsap\MBD5, Hsap\MBD6" viable wing vein DRSC13643 IK -2.070235085 -1.41869342 -1.231892304 -1.499617228 -1.699100309 0.903474607 FBgn0035522 CG1273 - http://flybase.org/reports/FBgn0035522 protein_coding_gene - - - "CG1273, 1273" - CG1273 11-Aug-17 DroID_v2017_08 "Drer\fndc1, Drer\abi3bpb" - Cele\F49E10.2 - "Mmus\Abi3bp, Mmus\Fndc1" "Hsap\ABI3BP, Hsap\FNDC1" "viable,fertile" FBgn0263441 CR43464 - http://flybase.org/reports/FBgn0263441 non_protein_coding_gene - - - CR43464 - CR43464 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084776 W220 W220 http://flybase.org/reports/FBgn0084776 gene - - - W220 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0045500 Gr22b Gustatory receptor 22b http://flybase.org/reports/FBgn0045500 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity with Gr5a olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from sequence or structural similarity with Gr5a response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | inferred from sequence model dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr22bP, Gr2940.4, CR31931, CG31931, Gr22b, GR22b" IPR013604:7TM chemoreceptor CG31931 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - "partially lethal - majority die,some die during pupal stage" FBgn0267568 CR45908 - http://flybase.org/reports/FBgn0267568 non_protein_coding_gene - - - CR45908 - CR45908 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001719 l(1)ESHS40 lethal (1) ESHS40 http://flybase.org/reports/FBgn0001719 - gene - - - l(1)ESHS40 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031422 PIG-Wa Phosphatidylinositol glycan anchor biosynthesis class W a http://flybase.org/reports/FBgn0031422 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR009447" GPI anchor biosynthetic process ; GO:0006506 | inferred from electronic annotation with InterPro:IPR009447 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009447 "CG9870, PIG-Wa, PIG-W" IPR009447:GWT1 CG9870 11-Aug-17 DroID_v2017_08 Drer\pigw Scer\GWT1 Cele\hpo-20 Xtro\pigw Mmus\Pigw Hsap\PIGW viable FBgn0264995 CR44146 - http://flybase.org/reports/FBgn0264995 non_protein_coding_gene - - - CR44146 - CR44146 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038114 CG11670 - http://flybase.org/reports/FBgn0038114 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP27, CG11670" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11670 11-Aug-17 DroID_v2017_08 - - "Cele\svh-1, Cele\try-3" - - Hsap\MASP1 "viable,fertile" FBgn0261991 CG42809 - http://flybase.org/reports/FBgn0261991 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42809, CG16849" - CG42809 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038251 Hexim Hexamethylene bisacetamide inducible http://flybase.org/reports/FBgn0038251 protein_coding_gene cyclin-dependent protein serine/threonine kinase inhibitor activity ; GO:0004861 | inferred from electronic annotation with InterPro:IPR024872 7SK snRNA binding ; GO:0097322 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from electronic annotation with InterPro:IPR024872 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR024872 nucleus ; GO:0005634 | inferred from direct assay "Hexim, dHEXIM, CG3508" IPR024872:HEXIM CG3508 11-Aug-17 DroID_v2017_08 Drer\hexim1 - - Xtro\hexim1 "Mmus\Hexim1, Mmus\Hexim2" "Hsap\HEXIM1, Hsap\HEXIM2" "lethal,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile" "leg,wing,eye" FBgn0028870 CG4691 - http://flybase.org/reports/FBgn0028870 protein_coding_gene - - - "BG:DS06874.1, anon-WO0140519.47, CG4691" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG4691 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266283 ddt double double trouble http://flybase.org/reports/FBgn0266283 gene - - - ddt - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,somatic clone,lethal,conditional" "eye,somatic clone,conditional" FBgn0052010 CR32010 - http://flybase.org/reports/FBgn0052010 pseudogene_attribute - - - "CG32010, CR32010" - CR32010 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016779 anon-77Bc anon-77Bc http://flybase.org/reports/FBgn0016779 - gene - - - "D, anon-77Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004123 l(2)43Bb lethal (2) 43Bb http://flybase.org/reports/FBgn0004123 - gene - - - "43Bb, l(2)04614, l(2)43Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020269 mspo M-spondin http://flybase.org/reports/FBgn0020269 - protein_coding_gene - regulation of myoblast fusion ; GO:1901739 | inferred from mutant phenotype - "CT28539, CG10145, mspo, Mspo, m-spo" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR009465:Spondin, N-terminal" CG10145 11-Aug-17 DroID_v2017_08 "Drer\spon2a, Drer\spon1a, Drer\spon2b, Drer\spon1b" - Cele\spon-1 Xtro\spon2 "Mmus\Spon1, Mmus\Spon2" "Hsap\SPON2, Hsap\SPON1" "viable,fertile" "dorsal acute muscle 1,nucleus | supernumerary,nucleuseve.eme" FBgn0036827 CG6843 - http://flybase.org/reports/FBgn0036827 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with HGNC:24217" nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24217 CG6843 "IPR019339:CBF1-interacting co-repressor CIR, N-terminal domain" CG6843 11-Aug-17 DroID_v2017_08 Drer\rp9 - Cele\cir-1 Xtro\cir1 "Mmus\Cir1, Mmus\Rp9" "Hsap\CIR1, Hsap\RP9" FBgn0264510 CR43909 - http://flybase.org/reports/FBgn0264510 non_protein_coding_gene - - - CR43909 - CR43909 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045859 csn casanova http://flybase.org/reports/FBgn0045859 gene - - - "ms(3)HB156, csn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile,viable,recessive" FBgn0284421 Psn Presenilin http://flybase.org/reports/FBgn0284421 protein_coding_gene "aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001108, InterPro:IPR006639 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Psn" intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001493 protein processing ; GO:0016485 | inferred from electronic annotation with InterPro:IPR001108 Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype copper ion import ; GO:0015677 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype membrane protein ectodomain proteolysis ; GO:0006509 | traceable author statement regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of heart rate ; GO:0002027 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | traceable author statement neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype "recycling endosome ; GO:0055037 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay gamma-secretase complex ; GO:0070765 | inferred from physical interaction with aph-1, nct, pen-2 cytoplasm ; GO:0005737 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay" "CG18803, Psn, psn, CG5868, PS, DPsn, Dps, PS1, DPS, pres, l(3)77CDb, DmPS, DrosPS, dPsn, PSN, 493/14, 0493/14, l(3)S049314, l(3)S049314a, 0480/15, l(3)S048015a" "IPR001493:Peptidase A22A, presenilin 2, IPR001108:Peptidase A22A, presenilin, IPR006639:Presenilin/signal peptide peptidase" CG18803 11-Aug-17 DroID_v2017_08 "Drer\psen2, Drer\psen1" - "Cele\sel-12, Cele\spe-4, Cele\hop-1" "Xtro\psen2, Xtro\psen1" "Mmus\Psen2, Mmus\Psen1" "Hsap\PSEN1, Hsap\PSEN2" "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259186 Ir60c Ionotropic receptor 60c http://flybase.org/reports/FBgn0259186 pseudogene_attribute - - - "CG13582, DmelIR60c, CG42290, Ir60c, IR60c, CR42290" - CR42290 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015001 iotaTry iotaTrypsin http://flybase.org/reports/FBgn0015001 - protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "143775_at, SP129, CG7754, iotaTry" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG7754 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.9, Drer\zgc:55888, Drer\si:ch211-165b19.8, Drer\LOC562139, Drer\zgc:112160, Drer\ctrl" - "Cele\svh-1, Cele\try-1" - "Mmus\Prss36, Mmus\Klk14, Mmus\Mcpt8, Mmus\Prss55, Mmus\Prss53" "Hsap\KLK14, Hsap\PRSS53, Hsap\PRSS36, Hsap\GZMB" viable FBgn0085334 CG34305 - http://flybase.org/reports/FBgn0085334 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34305 - CG34305 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261639 CR42722 - http://flybase.org/reports/FBgn0261639 pseudogene_attribute - - - CR42722 - CR42722 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051390 MED7 Mediator complex subunit 7 http://flybase.org/reports/FBgn0051390 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W5P1 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR009244 transcription from RNA polymerase II promoter ; GO:0006366 | inferred by curator from GO:0001104 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000484466 mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred by curator from GO:0001104 core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN000484466 "Med7, dMED7, dTRAP34, CG6529, CG31390, MED7" "IPR009244:Mediator complex, subunit Med7" CG31390 11-Aug-17 DroID_v2017_08 Drer\med7 Scer\MED7 Cele\let-49 Xtro\med7 Mmus\Med7 Hsap\MED7 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16059 IEK -2.266768988 1.656760997 -2.911276715 0.498031782 2.355447936 3.348135134 FBgn0037764 CG9459 - http://flybase.org/reports/FBgn0037764 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "CT26804, CG9459" "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG9459 11-Aug-17 DroID_v2017_08 "Drer\elovl4a, Drer\elovl8b, Drer\elovl1a, Drer\elovl5, Drer\elovl7a, Drer\elovl4b, Drer\elovl8a, Drer\elovl2, Drer\elovl1b, Drer\elovl7b" "Scer\ELO2, Scer\ELO1, Scer\ELO3" Cele\elo-9 "Xtro\elovl2, Xtro\elovl1, Xtro\elovl7, Xtro\elovl5" "Mmus\Elovl3, Mmus\Elovl7, Mmus\Elovl5, Mmus\Elovl4, Mmus\Elovl2, Mmus\Elovl1" "Hsap\ELOVL4, Hsap\ELOVL3, Hsap\ELOVL1, Hsap\ELOVL5, Hsap\ELOVL2, Hsap\ELOVL7" viable FBgn0085569 CG41242 - http://flybase.org/reports/FBgn0085569 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG41242 - CG41242 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052424 CG32424 - http://flybase.org/reports/FBgn0052424 protein_coding_gene - - - CG32424 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037313 CG1161 - http://flybase.org/reports/FBgn0037313 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008853 CG1161 IPR008853:TMEM9 CG1161 11-Aug-17 DroID_v2017_08 "Drer\tmem9, Drer\tmem9b" - Cele\R12C12.6 - "Mmus\Tmem9b, Mmus\Tmem9" "Hsap\TMEM9, Hsap\TMEM9B" lethal FBgn0011653 mas masquerade http://flybase.org/reports/FBgn0011653 - protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues peptidase activity ; GO:0008233 | NOT traceable author statement "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" plasma membrane ; GO:0005886 | inferred from direct assay "SPH79, c-SPH79, CG15002, mas" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG15002 11-Aug-17 DroID_v2017_08 - - Cele\svh-1 Xtro\cfi Mmus\Cfi "Hsap\CFI, Hsap\PLG, Hsap\PRSS21" " embryonic stage--pupal stage , embryonic stage | stage 12-17 , embryonic stage | stage 14-17 , embryonic stage | stage 11-13 " " epidermis

, tracheal system

, ventral midline | restricted

" " embryonic stage , embryonic stage | stage 14-17 " " tracheal system

, embryonic/larval tracheal system

, epidermis

" "smell perception defective,taste perception defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "lateral transverse muscle,ventral acute muscle,ventral longitudinal muscle,lateral oblique muscle 1,longitudinal connective,commissure,aCC neuron,pCC neuron,peripheral nervous system" FBgn0039359 RpL27 Ribosomal protein L27 http://flybase.org/reports/FBgn0039359 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001141, InterPro:IPR018262 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001141, InterPro:IPR018262 centrosome organization ; GO:0051297 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001141, InterPro:IPR018262 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "CG4759, RpL27, RpL27e, RPL27, chr3R:21510055..21510241" "IPR018262:Ribosomal protein L27e, conserved site, IPR001141:Ribosomal protein L27e, IPR005824:KOW, IPR008991:Translation protein SH3-like domain, IPR014722:Ribosomal protein L2 domain 2" CG4759 11-Aug-17 DroID_v2017_08 Drer\rpl27 "Scer\RPL27A, Scer\RPL27B" Cele\rpl-27 Xtro\rpl27 "Mmus\LOC108167922, Mmus\Rpl27" Hsap\RPL27 lethal DRSC15638 EK -1.495305073 -0.258025489 0.356025419 -4.000192804 1.491885399 4.7943074 FBgn0002779 mo micro-oculus http://flybase.org/reports/FBgn0002779 - gene - - - mo - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" "eye,wing,wing hair" FBgn0003035 par paralog http://flybase.org/reports/FBgn0003035 - gene molecular_function ; GO:0003674 | no biological data available nuclear migration ; GO:0007097 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "fs(1)A1122[ts], fs(1)A1122, par" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,maternal effect,recessive,heat sensitive" "ovary,maternal effect,heat sensitive,egg chamber,blastoderm embryo,pole cell,gonad,adult cuticle,wing vein,cleavage nucleus" FBgn0038922 CG6439 - http://flybase.org/reports/FBgn0038922 protein_coding_gene isocitrate dehydrogenase (NAD+) activity ; GO:0004449 | inferred from sequence or structural similarity with UniProtKB:O43837 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:O43837 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O43837 microtubule associated complex ; GO:0005875 | inferred from direct assay "FBgn0038922, CG6439, Idh" "IPR004434:Isocitrate dehydrogenase NAD-dependent, IPR024084:Isopropylmalate dehydrogenase-like domain" CG6439 11-Aug-17 DroID_v2017_08 "Drer\idh3b, Drer\idh3a, Drer\idh3g" Scer\IDH1 "Cele\idha-1, Cele\idhg-2, Cele\idhb-1, Cele\idhg-1" "Xtro\idh3g, Xtro\idh3a, Xtro\idh3b" "Mmus\Idh3g, Mmus\4933405O20Rik, Mmus\Idh3a, Mmus\Idh3b" "Hsap\IDH3A, Hsap\IDH3B, Hsap\IDH3G" "lethal,viable,fertile,partially lethal - majority die" FBgn0011166 l(1)DM-3 lethal (1) DM-3 http://flybase.org/reports/FBgn0011166 FBgn0010204 gene - - - l(1)DM-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0082688 E(ftz)1815 E(ftz)1815 http://flybase.org/reports/FBgn0082688 gene - - - "1815, E(ftz)1815" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001194 hir heterochromatic recombination inducer http://flybase.org/reports/FBgn0001194 - gene - - - hir - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259556 B2011 - http://flybase.org/reports/FBgn0259556 gene - - - B2011 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000899 fs(1)M108 female sterile (1) M108 http://flybase.org/reports/FBgn0000899 - gene - - - fs(1)M108 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0262899 CG43254 - http://flybase.org/reports/FBgn0262899 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43254, lincRNA.715" - CG43254 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000026 acj2 abnormal chemosensory jump 2 http://flybase.org/reports/FBgn0000026 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,recessive" FBgn0040513 kappaB-Ras kappaB-Ras http://flybase.org/reports/FBgn0040513 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR020849 GTP binding ; GO:0005525 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with cact GTPase activity ; GO:0003924 | NOT inferred from sequence model" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 negative regulation of I-kappaB kinase/NF-kappaB signaling ; GO:0043124 | inferred from sequence or structural similarity membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 "dkappaB-Ras, kappaB-Ras, CG1669, BcDNA:RH38596, B7YZS7, Q9V4L4-1" "IPR001806:Small GTPase superfamily, IPR020849:Small GTPase superfamily, Ras type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1669 11-Aug-17 DroID_v2017_08 "Drer\LOC100332969, Drer\rap2ab, Drer\rap2b, Drer\nkiras1, Drer\nkiras2, Drer\rap2c" - "Cele\rap-2, Cele\ZK669.5, Cele\kbrl-1, Cele\D1081.4, Cele\rap-3, Cele\Y52B11A.4" "Xtro\nkiras2, Xtro\nkiras1" "Mmus\Rap2b, Mmus\Nkiras2, Mmus\Gm266, Mmus\Nkiras1, Mmus\Rap2a, Mmus\Rap2c" "Hsap\RAP2C, Hsap\NKIRAS2, Hsap\RAP2A, Hsap\RAP2B, Hsap\NKIRAS1" FBgn0260755 CG42553 - http://flybase.org/reports/FBgn0260755 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13886, CT33419, CG42553" IPR010733:Protein of unknown function DUF1308 CG42553 11-Aug-17 DroID_v2017_08 Drer\zgc:55781 - Cele\F33G12.3 Xtro\c7orf25 Mmus\AW209491 Hsap\C7orf25 FBgn0003590 Su(var)2-3 Suppressor of variegation 2-3 http://flybase.org/reports/FBgn0003590 - gene - - - "Su-var(2)3, Su(var)2-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0023436 ifa irregular facet http://flybase.org/reports/FBgn0023436 - gene - - - ifa - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "pigment cell,ommatidium" FBgn0037636 CG9821 - http://flybase.org/reports/FBgn0037636 protein_coding_gene - - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001034975 "CG31442, anon-WO0118547.424, anon-WO0118547.399, CG9821, Ov29" IPR026780:Proline-rich nuclear receptor coactivator 1/2 CG9821 11-Aug-17 DroID_v2017_08 "Drer\pnrc1, Drer\pnrc2" - - - "Mmus\Pnrc2, Mmus\Pnrc1" "Hsap\PNRC1, Hsap\PNRC2" "lethal,viable,fertile,neuroanatomy defective" "presumptive embryonic/larval peripheral nervous system,ventral nerve cord commissure" DRSC16570 EK -0.611206603 0.813672327 -0.525268671 -3.069052823 2.284551098 1.981705373 FBgn0262099 CG42852 - http://flybase.org/reports/FBgn0262099 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42852, lincRNA.585" - CG42852 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085256 CG34227 - http://flybase.org/reports/FBgn0085256 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from direct assay "CG34227, CG7738" - CG34227 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266683 CR45173 - http://flybase.org/reports/FBgn0266683 non_protein_coding_gene - - - CR45173 - CR45173 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025684 MFS18 Major Facilitator Superfamily Transporter 18 http://flybase.org/reports/FBgn0025684 FBgn0031605 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "CK02623, BEST:CK02623, CG15438, MFS18" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG15438 11-Aug-17 DroID_v2017_08 "Drer\slc17a9a, Drer\slc17a9b" "Scer\THI73, Scer\YIL166C, Scer\TNA1, Scer\DAL5" "Cele\cima-1, Cele\slc-17.9, Cele\vnut-1" Xtro\slc17a9 Mmus\Slc17a9 Hsap\SLC17A9 viable FBgn0030314 CG11696 - http://flybase.org/reports/FBgn0030314 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "b, CG11696" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG11696 11-Aug-17 DroID_v2017_08 "Drer\znf865, Drer\zgc:153116, Drer\prdm5" - "Cele\klf-3, Cele\klu-1, Cele\Y55F3AM.14" - "Mmus\Zfp212, Mmus\Zfp865, Mmus\Zfp667" "Hsap\ZNF805, Hsap\ZSCAN12, Hsap\ZNF865, Hsap\ZNF667, Hsap\ZNF783, Hsap\ZNF254, Hsap\ZNF671, Hsap\ZNF662, Hsap\PRDM5, Hsap\ZNF212, Hsap\ZNF763" FBgn0085276 CG34247 - http://flybase.org/reports/FBgn0085276 protein_coding_gene - - - CG34247 - CG34247 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051720 mthl15 methuselah-like 15 http://flybase.org/reports/FBgn0051720 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 response to stress ; GO:0006950 | inferred from electronic annotation with InterPro:IPR010596 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with mth "CG31720, mthl15" "IPR017981:GPCR, family 2-like, IPR023311:Methuselah ectodomain, domain 2, IPR000832:GPCR, family 2, secretin-like, IPR010596:Methuselah, N-terminal domain" CG31720 11-Aug-17 DroID_v2017_08 Drer\adgrf11 - - Xtro\gpr157 Mmus\Adgrb2 - FBgn0265309 CR44282 - http://flybase.org/reports/FBgn0265309 non_protein_coding_gene - - - CR44282 - CR44282 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264785 Hph HIF prolyl hydroxylase http://flybase.org/reports/FBgn0264785 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620 iron ion binding ; GO:0005506 | inferred from sequence model peptidyl-proline 4-dioxygenase activity ; GO:0031545 | inferred from sequence or structural similarity with HGNC:1232,HGNC:14660,HGNC:14661 zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 peptidyl-proline dioxygenase activity ; GO:0031543 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from genetic interaction with CycD, Cdk4 positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype peptidyl-proline hydroxylation ; GO:0019511 | inferred from direct assay response to hypoxia ; GO:0001666 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype peptidyl-proline hydroxylation to 4-hydroxy-L-proline ; GO:0018401 | inferred from sequence or structural similarity with HGNC:1232,HGNC:14660,HGNC:14661 protein export from nucleus ; GO:0006611 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from direct assay "Hph, PHD, hph, dPHD, CG44015, CG31543, dPHD2, fga, CG14665, l(3)02255, CG1114, dmHPH, Dm.egl-9, 0303/04, anon-EST:Posey69, l(3)S030304, dHPH, 31543, l(3)82Fe, CG2676, CR31541, fatiga, FgaB" "IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR002893:Zinc finger, MYND-type" CG44015 11-Aug-17 DroID_v2017_08 "Drer\egln1a, Drer\taf5, Drer\egln2, Drer\egln1b, Drer\egln3" - Cele\egl-9 "Xtro\taf5l, Xtro\egln3, Xtro\taf5, Xtro\egln1, Xtro\egln2" "Mmus\Egln2, Mmus\Egln1, Mmus\Taf5l, Mmus\Egln3, Mmus\Taf5" "Hsap\EGLN3, Hsap\TAF5, Hsap\EGLN2, Hsap\EGLN1, Hsap\TAF5L" FBgn0064155 oosy out of sync http://flybase.org/reports/FBgn0064155 gene - nuclear axial expansion ; GO:0035191 | inferred from mutant phenotype nuclear cortical migration ; GO:0035192 | inferred from mutant phenotype regulation of preblastoderm mitotic cell cycle ; GO:0007347 | inferred from mutant phenotype - oosy - - 11-Aug-17 DroID_v2017_08 - - - - - - "pole cell,maternal effect,cleavage nucleus,germline clone" FBgn0266535 CR45096 - http://flybase.org/reports/FBgn0266535 non_protein_coding_gene - - - CR45096 - CR45096 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053902 His2B:CG33902 His2B:CG33902 http://flybase.org/reports/FBgn0053902 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33902, His2B:CG33902" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33902 11-Aug-17 DroID_v2017_08 "Drer\LOC100329560, Drer\LOC100329290, Drer\si:ch1073-159d7.13, Drer\hist2h2l, Drer\si:dkey-108k21.27, Drer\si:ch211-113a14.28, Drer\si:ch1073-153i20.3, Drer\zgc:194989, Drer\si:dkey-261m9.19, Drer\ano9a, Drer\si:ch1073-159d7.5, Drer\si:ch211-113a14.29, Drer\si:dkey-23a13.1, Drer\si:ch73-368j24.8, Drer\zgc:173587, Drer\si:dkey-261m9.6, Drer\si:dkey-108k21.11, Drer\si:ch73-36p18.3, Drer\zgc:114046, Drer\zgc:173585, Drer\LOC100334559, Drer\si:ch211-113a14.11, Drer\LOC100334869, Drer\si:dkey-23a13.5, Drer\hist1h2ba, Drer\si:dkey-23a13.16, Drer\zgc:92591" "Scer\HTB2, Scer\HTB1" "Cele\his-20, Cele\his-66, Cele\his-4, Cele\his-8, Cele\his-41, Cele\his-54, Cele\his-15, Cele\his-48, Cele\his-58, Cele\his-22, Cele\his-39, Cele\his-11, Cele\his-29, Cele\his-62, Cele\his-44, Cele\his-34, Cele\his-52" "Xtro\LOC101731959, Xtro\LOC100498647, Xtro\LOC100486870, Xtro\LOC101733171, Xtro\LOC100496445, Xtro\hist1h2bj, Xtro\LOC100487485, Xtro\LOC100495041, Xtro\LOC100496436, Xtro\hist1h2bm, Xtro\LOC101734862, Xtro\LOC101731067, Xtro\LOC100496181, Xtro\LOC100485294, Xtro\LOC101733489, Xtro\LOC100497915, Xtro\hist2h2be, Xtro\LOC100486150, Xtro\hist1h2bk, Xtro\LOC100495578, Xtro\LOC101735164, Xtro\LOC100497082, Xtro\LOC100492632, Xtro\LOC101731852, Xtro\LOC101735218, Xtro\LOC100495396, Xtro\LOC100498072, Xtro\LOC100495415, Xtro\LOC101733828, Xtro\LOC100498329, Xtro\LOC100498553, Xtro\LOC100485134, Xtro\LOC101734494, Xtro\LOC101730940" "Mmus\Hist2h2be, Mmus\Hist1h2bn, Mmus\Hist1h2bh, Mmus\Hist1h2bq, Mmus\Hist1h2bp, Mmus\Hist1h2bf, Mmus\Hist1h2ba, Mmus\Hist1h2bj, Mmus\Hist1h2bk, Mmus\Hist1h2br, Mmus\Hist1h2bb, Mmus\Hist1h2bc, Mmus\Hist3h2ba, Mmus\Hist2h2bb, Mmus\Hist1h2be, Mmus\Hist1h2bm, Mmus\Hist1h2bl, Mmus\H2bfm, Mmus\1700024P04Rik, Mmus\Hist1h2bg" "Hsap\HIST1H2BM, Hsap\H2BFM, Hsap\HIST1H2BA, Hsap\HIST1H2BF, Hsap\HIST3H2BB, Hsap\HIST2H2BE, Hsap\HIST2H2BF, Hsap\HIST1H2BL, Hsap\HIST1H2BG, Hsap\HIST1H2BO, Hsap\HIST1H2BI, Hsap\H2BFWT, Hsap\HIST1H2BC, Hsap\HIST1H2BE, Hsap\HIST1H2BN, Hsap\HIST1H2BD, Hsap\HIST1H2BJ, Hsap\HIST1H2BH, Hsap\HIST1H2BB, Hsap\HIST1H2BK" FBgn0259111 Ndae1 Na[+]-driven anion exchanger 1 http://flybase.org/reports/FBgn0259111 protein_coding_gene "inorganic anion exchanger activity ; GO:0005452 | inferred from electronic annotation with InterPro:IPR001717, InterPro:IPR003020, InterPro:IPR003024 anion:anion antiporter activity ; GO:0015301 | inferred from direct assay" proton transport ; GO:0015992 | inferred from direct assay regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000894242 sodium ion transport ; GO:0006814 | inferred from direct assay bicarbonate transport ; GO:0015701 | inferred from direct assay anion transport ; GO:0006820 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000894242 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG4675, Ndae1, CG42253, 153385_at, ndae1, NDAE1, l(2)k10316, Ndae-1, anon-WO0257455.13, CG31906" "IPR003020:Bicarbonate transporter, eukaryotic, IPR003024:Sodium bicarbonate cotransporter, IPR011531:Bicarbonate transporter, C-terminal, IPR013769:Band 3 cytoplasmic domain, IPR016152:Phosphotransferase/anion transporter, IPR001717:Anion exchange protein" CG42253 11-Aug-17 DroID_v2017_08 "Drer\slc4a5, Drer\nek10, Drer\slc4a8, Drer\slc4a4b, Drer\slc4a2b, Drer\LOC557642, Drer\slc4a2a, Drer\slc4a10a, Drer\slc4a1a, Drer\slc4a4a, Drer\si:ch211-48m9.1, Drer\slc4a7, Drer\slc4a11, Drer\slc4a1b, Drer\slc4a3" Scer\BOR1 "Cele\abts-3, Cele\abts-2, Cele\abts-4, Cele\abts-1" "Xtro\slc4a7, Xtro\slc4a10, Xtro\slc4a4, Xtro\slc4a8, Xtro\slc4a3, Xtro\slc4a1, Xtro\slc4a5, Xtro\nek10, Xtro\slc4a11" "Mmus\Slc4a1, Mmus\Slc4a3, Mmus\Nek10, Mmus\Slc4a5, Mmus\Slc4a9, Mmus\Slc4a4, Mmus\Slc4a2, Mmus\Slc4a11, Mmus\Slc4a8, Mmus\Slc4a7, Mmus\Slc4a10" "Hsap\NEK10, Hsap\SLC4A1, Hsap\SLC4A10, Hsap\SLC4A8, Hsap\SLC4A9, Hsap\SLC4A11, Hsap\SLC4A7, Hsap\SLC4A2, Hsap\SLC4A5, Hsap\SLC4A3, Hsap\SLC4A4" FBgn0053732 snmRNA:430:CR33732 snmRNA:430:CR33732 http://flybase.org/reports/FBgn0053732 non_protein_coding_gene - - - "CR33732, snmRNA:430:CR33732" - CR33732 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000326 clt cricklet http://flybase.org/reports/FBgn0000326 "FBgn0027353, FBgn0034640" protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | non-traceable author statement carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 male mating behavior ; GO:0060179 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "CG9858, anon-57Fb, clt, Est-R" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR029058:Alpha/Beta hydrolase fold" CG9858 11-Aug-17 DroID_v2017_08 "Drer\ces2, Drer\nlgn4a, Drer\si:ch211-93f2.1, Drer\nlgn2a, Drer\cel.1, Drer\ces3, Drer\nlgn3b, Drer\nlgn2b, Drer\nlgn1, Drer\nlgn4b, Drer\cell, Drer\nlgn3a" - "Cele\C52A10.1, Cele\F56C11.6, Cele\B0238.7, Cele\F13H6.3, Cele\C17H12.4, Cele\T28C12.4, Cele\K07C11.4, Cele\B0238.1, Cele\F15A8.6, Cele\T28C12.5, Cele\K11G9.3, Cele\C01B10.4, Cele\R173.3, Cele\W02B12.4, Cele\C01B10.10, Cele\ges-1, Cele\Y71H2AM.13, Cele\T07H6.1, Cele\T02B5.3, Cele\K11G9.1, Cele\F07C4.12, Cele\K11G9.2" "Xtro\LOC100494782, Xtro\cel, Xtro\ces3, Xtro\nlgn2, Xtro\ces2, Xtro\nlgn3, Xtro\nlgn4x" "Mmus\Ces1d, Mmus\Cel, Mmus\Ces2c, Mmus\Ces1e, Mmus\Ces2f, Mmus\Ces2g, Mmus\Nlgn1, Mmus\Ces1f, Mmus\Ces2a, Mmus\Ces3b, Mmus\Ces1b, Mmus\Ces4a, Mmus\Bche, Mmus\Ces3a, Mmus\Ces1h, Mmus\Ces1g, Mmus\Ces2h, Mmus\Ces2e, Mmus\Ces1c, Mmus\Ces5a, Mmus\Nlgn2, Mmus\Nlgn3, Mmus\Ces2b" "Hsap\CEL, Hsap\CES1, Hsap\CES4A, Hsap\CES5A, Hsap\BCHE, Hsap\NLGN2, Hsap\CES2, Hsap\NLGN1, Hsap\NLGN4Y, Hsap\CES3, Hsap\NLGN4X, Hsap\NLGN3" "stress response defective,mating defective,male,recessive" "oocyte,embryonic/larval fat body" FBgn0040486 BobB Brother of Bearded B http://flybase.org/reports/FBgn0040486 gene protein binding ; GO:0005515 | inferred from physical interaction with neur - - "Bob-B, Bob, BobB" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052233 CG32233 - http://flybase.org/reports/FBgn0052233 protein_coding_gene - - - CG32233 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039092 CG16723 - http://flybase.org/reports/FBgn0039092 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG16723 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG16723 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\nrf-6, Cele\oac-9, Cele\oac-55, Cele\ndg-4, Cele\oac-5, Cele\oac-3, Cele\oac-31, Cele\oac-53, Cele\oac-46, Cele\oac-50, Cele\oac-39, Cele\rhy-1, Cele\oac-20, Cele\oac-32, Cele\oac-6, Cele\oac-14, Cele\oac-54, Cele\oac-7" Xtro\LOC101732251 Mmus\Oacyl - "partially lethal - majority die,some die during pupal stage" FBgn0260318 GSd317 - http://flybase.org/reports/FBgn0260318 gene - - - GSd317 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0086302 polk polka dot http://flybase.org/reports/FBgn0086302 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - polk - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0050372 Asap "ArfGAP with SH3 domain, ankyrin repeat and PH domain" http://flybase.org/reports/FBgn0050372 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 phosphatidylinositol phosphate binding ; GO:1901981 | inferred from sequence or structural similarity with MGI:MGI:1342335 GTPase activator activity ; GO:0005096 | inferred from sequence model regulation of GTPase activity ; GO:0043087 | inferred from sequence model cytoplasm ; GO:0005737 | inferred from direct assay adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay "CG2226, CG14758, CG30372, dAsap, Asap, Asap1, ASAP" "IPR001164:Arf GTPase activating protein, IPR001452:SH3 domain, IPR001849:Pleckstrin homology domain, IPR002110:Ankyrin repeat, IPR011993:PH domain-like, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR020683:Ankyrin repeat-containing domain" CG30372 11-Aug-17 DroID_v2017_08 "Drer\zgc:162872, Drer\acap3a, Drer\asap1a, Drer\acap3b, Drer\si:ch211-168b3.1, Drer\asap3, Drer\asap1b, Drer\appl1, Drer\asap2a, Drer\asap2b, Drer\appl2, Drer\unm_sa1614" "Scer\AGE1, Scer\AGE2, Scer\GTS1" - "Xtro\acap1, Xtro\asap1, Xtro\acap3, Xtro\appl1, Xtro\arap3, Xtro\appl2, Xtro\acap2, Xtro\asap2" "Mmus\Acap1, Mmus\Asap3, Mmus\Appl2, Mmus\9030624G23Rik, Mmus\Appl1, Mmus\Acap3, Mmus\Asap2, Mmus\Acap2, Mmus\Asap1" "Hsap\ASAP3, Hsap\ACAP2, Hsap\APPL2, Hsap\APPL1, Hsap\ASAP1, Hsap\ACAP1, Hsap\ACAP3, Hsap\ASAP2" viable FBgn0004429 LysP Lysozyme P http://flybase.org/reports/FBgn0004429 FBgn0002575 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 lysozyme activity ; GO:0003796 | inferred from sequence or structural similarity - - "LysP, lysP, CG9116" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CG9116 11-Aug-17 DroID_v2017_08 "Drer\LOC100536671, Drer\lyz, Drer\LOC100334363" - - Xtro\MGC89221 "Mmus\Lalba, Mmus\Spaca5, Mmus\Spaca7, Mmus\Spaca3, Mmus\9530003J23Rik, Mmus\Spaca1, Mmus\Spaca4, Mmus\Lyz1, Mmus\Lyz2, Mmus\Lyzl6, Mmus\Lyzl4, Mmus\1700016D06Rik, Mmus\Lyzl1" "Hsap\LALBA, Hsap\SPACA4, Hsap\SPACA7, Hsap\LYZL6, Hsap\SPACA3, Hsap\LYZL4, Hsap\LYZL1, Hsap\SPACA1, Hsap\LYZ, Hsap\SPACA5, Hsap\SPACA5B, Hsap\LYZL2" adult stage adult salivary gland

viable FBgn0085329 CG34300 - http://flybase.org/reports/FBgn0085329 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34300 - CG34300 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065638 l(2)SH0764 lethal (2) SH0764 http://flybase.org/reports/FBgn0065638 gene - - - "l(2)SH0764, l(2)SH2 0764" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021998 l(2)k09328 lethal (2) k09328 http://flybase.org/reports/FBgn0021998 - gene - - - l(2)k09328 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021883 l(2)k13412 lethal (2) k13412 http://flybase.org/reports/FBgn0021883 - gene - - - l(2)k13412 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038437 Sdhaf3 Succinate dehydrogenase assembly factor 3 http://flybase.org/reports/FBgn0038437 protein_coding_gene - musculoskeletal movement ; GO:0050881 | inferred from mutant phenotype mitochondrial respiratory chain complex II assembly ; GO:0034553 | inferred from biological aspect of ancestor with PANTHER:PTN000320077 regulation of gluconeogenesis ; GO:0006111 | inferred from biological aspect of ancestor with PANTHER:PTN000320077 succinate metabolic process ; GO:0006105 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype response to hyperoxia ; GO:0055093 | inferred from mutant phenotype mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN000320077 "BcDNA:RE23580, Sdhaf3, CG14898, sdh7, dSdhaf3, Sdh7" IPR008381:ACN9 CG14898 11-Aug-17 DroID_v2017_08 Drer\sdhaf3 Scer\SDH7 Cele\F25H9.7 Xtro\sdhaf3 Mmus\Sdhaf3 Hsap\SDHAF3 viable DRSC15020 K -0.130708578 0.83602864 0.429028768 0.487062194 0.358231109 4.842556114 FBgn0051887 CG31887 - http://flybase.org/reports/FBgn0051887 protein_coding_gene - - - CG31887 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024525 l(3)j5E7 lethal (3) j5E7 http://flybase.org/reports/FBgn0024525 - gene - - - l(3)j5E7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0063909 N::Mmus\Notch1 Notch1 http://flybase.org/reports/FBgn0063909 engineered_fusion_gene - - - N::Mmus\Notch1 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "dorsal abdominal cluster,presumptive embryonic/larval peripheral nervous system,S2 cell-line" FBgn0040735 CG16836 - http://flybase.org/reports/FBgn0040735 protein_coding_gene - - - CG16836 IPR013172:Immune-induced protein Dim CG16836 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0082376 E(GMR-wIR)A28 Enhancer(GMR-wIR)A28 http://flybase.org/reports/FBgn0082376 gene - - - E(GMR-wIR)A28 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004781 Ccp84Ac Ccp84Ac http://flybase.org/reports/FBgn0004781 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "cc6, CG1327, BG:DS00004.3, Ccp84Ac, Ccp, DmelCcp84Ac" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG1327 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC12588 K 0.444798667 0.296208733 -0.002042957 0.016943411 1.099519121 -1.759340902 FBgn0036890 CG9368 - http://flybase.org/reports/FBgn0036890 protein_coding_gene - - - "BcDNA:RH51268, CG9368" - CG9368 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC11067 I -0.326665271 1.646061633 -0.168937514 0.147620142 -0.11164128 -0.566697809 FBgn0026168 spnl space-needle http://flybase.org/reports/FBgn0026168 - gene - - - spnl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028406 Drep4 DNA fragmentation factor-related protein 4 http://flybase.org/reports/FBgn0028406 protein_coding_gene deoxyribonuclease activity ; GO:0004536 | inferred from biological aspect of ancestor with PANTHER:PTN000990874 apoptotic DNA fragmentation ; GO:0006309 | inferred from electronic annotation with InterPro:IPR015311 apoptotic DNA fragmentation ; GO:0006309 | traceable author statement cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR015311 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000990874 "dCAD, CG9414, CAD, drep4, DREP-4, Rep4, Drep4, Drep-4" "IPR003508:CIDE-N domain, IPR015311:Apoptosis, DNA fragmentation factor 40kDa" CG9414 11-Aug-17 DroID_v2017_08 "Drer\impa2, Drer\dffb" "Scer\INM1, Scer\INM2" - "Xtro\dffb, Xtro\impa1" "Mmus\Impa1, Mmus\Dffb" "Hsap\IMPA1, Hsap\DFFB" viable FBgn0267888 CR46176 - http://flybase.org/reports/FBgn0267888 pseudogene_attribute - - - "CR46176, CG12717-related" - CR46176 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069998 BG01656 BG01656 http://flybase.org/reports/FBgn0069998 gene - - - BG01656 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0039641 CG14511 - http://flybase.org/reports/FBgn0039641 protein_coding_gene GDP-fucose transmembrane transporter activity ; GO:0005457 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 UDP-xylose transmembrane transporter activity ; GO:0005464 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 UDP-N-acetylglucosamine transmembrane transporter activity ; GO:0005462 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 UDP-N-acetylglucosamine transmembrane transport ; GO:1990569 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 GDP-fucose transport ; GO:0015783 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 Golgi medial cisterna ; GO:0005797 | inferred from direct assay integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 CG14511 IPR013657:UAA transporter CG14511 11-Aug-17 DroID_v2017_08 Drer\slc35b4 Scer\YEA4 "Cele\nstp-1, Cele\nstp-2" - Mmus\Slc35b4 Hsap\SLC35B4 viable FBgn0259424 EP-650 - http://flybase.org/reports/FBgn0259424 gene - - - EP-650 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing" FBgn0053377 5SrRNA:CR33377 5SrRNA:CR33377 http://flybase.org/reports/FBgn0053377 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33377, 5SrRNA:CR33377" - CR33377 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004407 DNApol-gamma35 DNA polymerase gamma 35kD http://flybase.org/reports/FBgn0004407 "FBgn0000476, FBgn0001962, FBgn0020398, FBgn0053084, FBgn0053650, FBtr0089832, FBpp0088773, FBtr0089833, FBpp0088774" protein_coding_gene DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity with UniProtKB:Q9UHN1 glycine-tRNA ligase activity ; GO:0004820 | inferred from biological aspect of ancestor with PANTHER:PTN000078674 axonal transport of mitochondrion ; GO:0019896 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from physical interaction with tam mitochondrial DNA replication ; GO:0006264 | traceable author statement glycyl-tRNA aminoacylation ; GO:0006426 | inferred from biological aspect of ancestor with PANTHER:PTN000078674 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from sequence or structural similarity with UniProtKB:Q9UHN1 mitochondrial genome maintenance ; GO:0000002 | inferred from mutant phenotype mitochondrial DNA replication ; GO:0006264 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from physical interaction with tam gamma DNA polymerase complex ; GO:0005760 | inferred from physical interaction with tam mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9UHN1 gamma DNA polymerase complex ; GO:0005760 | inferred from sequence or structural similarity "pol gamma-beta, l(2)34De, polgamma-beta, MtPolB, BG:DS00941.9, polgamma, Polgamma, l(2)br16, DNApol-gamma, br16, CG33084, CG33650, CG8969, DNApol-gamma35, DNA pol-gam.35, DNApol-gamma.35, D-pol gamma-beta, pol gamma35, PolG, Pol gamma, Polg" "IPR004154:Anticodon-binding, IPR027031:Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2" CG33650 11-Aug-17 DroID_v2017_08 "Drer\gars, Drer\polg2" "Scer\GRS1, Scer\GRS2" - "Xtro\polg2, Xtro\gars" "Mmus\Gars, Mmus\Polg2" "Hsap\GARS, Hsap\POLG2" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,locomotor behavior defective" "mitochondrion,embryonic/larval central nervous system,mitochondrionb80c1)" FBgn0025007 E(var)102-1 E(var)102-1 http://flybase.org/reports/FBgn0025007 - gene - - - "E-102/1, E(var)102-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002403 l(3)99Dd lethal (3) 99Dd http://flybase.org/reports/FBgn0002403 - gene - - - l(3)99Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260763 CG42561 - http://flybase.org/reports/FBgn0260763 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14481, CG42561" - CG42561 11-Aug-17 DroID_v2017_08 - - - - - - DRSC05676 K 0.01097758 -0.362677984 -0.134144017 0.583906239 1.618992325 -0.442379407 FBgn0265810 CR44599 - http://flybase.org/reports/FBgn0265810 non_protein_coding_gene - - - CR44599 - CR44599 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053192 MtnD Metallothionein D http://flybase.org/reports/FBgn0053192 protein_coding_gene metal ion binding ; GO:0046872 | inferred from direct assay response to metal ion ; GO:0010038 | inferred from sequence or structural similarity with MtnE metal ion homeostasis ; GO:0055065 | inferred from mutant phenotype response to metal ion ; GO:0010038 | inferred from direct assay response to copper ion ; GO:0046688 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "CG33192, MtnD, mtnD" "IPR000966:Metallothionein, family 5, Diptera" CG33192 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22733 K 0.427786275 0.495561886 1.043114874 -0.407423976 -1.582004459 0.296703443 FBgn0004075 ms(2)35Eb male sterile (2) 35Eb http://flybase.org/reports/FBgn0004075 - gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(2)35Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0041719 snRNA:U4:25F snRNA:U4:25F http://flybase.org/reports/FBgn0041719 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U4 snRNP ; GO:0005687 | inferred from sequence or structural similarity "U4, U4-25F, K3, U4-2, dU4, snRNA:U4, CR32998, U4snRNA, snRNA:U4:25F, U4:25F, U4 snRNA, snRNA, U425F, U4-snRNA" - CR32998 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022045 l(2)k08306 lethal (2) k08306 http://flybase.org/reports/FBgn0022045 - gene - - - l(2)k08306 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060655 l(3)S082908a lethal (3) S082908a http://flybase.org/reports/FBgn0060655 gene - - - "0829/08, l(3)S082908a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0053465 CG33465 - http://flybase.org/reports/FBgn0053465 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "BP1080, CR33465, HDC06631, CG33465" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG33465 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\LOC558805" - Cele\try-3 - - Hsap\PRSS54 FBgn0044324 Chro Chromator http://flybase.org/reports/FBgn0044324 protein_coding_gene "histone binding ; GO:0042393 | inferred from physical interaction with His1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z8P9 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCH5,UniProtKB:Q9VGA4,UniProtKB:Q9VP57" chromosome organization ; GO:0051276 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype metaphase plate congression ; GO:0051310 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "Chriz, Chr, CG10712, anon-EST:fe2E3, Chro, CHRO, Chromator, Chiz, CHRIZ, CHRIZ/CHRO, Chro(Chriz)" "IPR000953:Chromo/chromo shadow domain, IPR016197:Chromo domain-like, IPR023780:Chromo domain, IPR029058:Alpha/Beta hydrolase fold" CG10712 11-Aug-17 DroID_v2017_08 "Drer\cbx3a, Drer\cbx3b" - "Cele\set-31, Cele\hpl-1" - Mmus\Cbx3 Hsap\CBX3 "lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,size defective,lethal - all die before end of larval stage,some die during third instar larval stage" "abdominal temporary eclosion muscle DA,A1-7 dorsal oblique muscle,wing,embryonic/larval neuroblast,imaginal disc,embryonic/larval brain,spindle | third instar larval stage,polytene chromosome" DRSC11630 EK -1.202313509 -1.343129555 -1.505271314 -1.25953784 2.164606305 0.181784419 FBgn0036324 CG12520 - http://flybase.org/reports/FBgn0036324 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG12520, FBgn0036324" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG12520 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0265730 CR44537 - http://flybase.org/reports/FBgn0265730 non_protein_coding_gene - - - "CR44537, incRNA.408, lincRNA.408" - CR44537 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050027 CG30027 - http://flybase.org/reports/FBgn0050027 protein_coding_gene - - - CG30027 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264384 CR43836 - http://flybase.org/reports/FBgn0264384 non_protein_coding_gene - - - CR43836 - CR43836 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263539 mir-4978 mir-4978 stem loop http://flybase.org/reports/FBgn0263539 miRNA_gene - - - "mir-4978, dme-mir-4978, CR43524" - CR43524 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264469 CR43877 - http://flybase.org/reports/FBgn0264469 non_protein_coding_gene - - - CR43877 - CR43877 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267524 2SrRNA:CR45864 2S ribosomal RNA:CR45864 http://flybase.org/reports/FBgn0267524 rRNA_gene - - - "2SrRNA:CR45864, CR45864" - CR45864 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022311 l(1)J30.4 lethal (1) J30.4 http://flybase.org/reports/FBgn0022311 - gene - - - "J30.4, l(1)J30.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060926 l(3)S042203b lethal (3) S042203b http://flybase.org/reports/FBgn0060926 gene - - - "0422/03, l(3)S042203b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0020060 E(spl)m8-HLH::h E(spl)::h http://flybase.org/reports/FBgn0020060 - engineered_fusion_gene - - - "E(spl)::h, E(spl)m8-HLH::h" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female" FBgn0061096 l(3)S009911 lethal (3) S009911 http://flybase.org/reports/FBgn0061096 gene - - - "0099/11, l(3)S009911" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262509 nrm neuromusculin http://flybase.org/reports/FBgn0262509 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synaptic target recognition ; GO:0008039 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from sequence or structural similarity inferred from direct assay "nrm, CG32458, CG43079, CT16082, CG8779, CG41452, CG4307" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2" CG43079 11-Aug-17 DroID_v2017_08 Drer\si:dkey-234i14.9 - Cele\egl-15 "Xtro\LOC100498328, Xtro\LOC100497709, Xtro\LOC100216153" "Mmus\Ceacam11, Mmus\Psg27, Mmus\Psg19, Mmus\F830045P16Rik, Mmus\Psg23, Mmus\Btnl2, Mmus\Sirpa, Mmus\Ceacam10, Mmus\Sirpb1a, Mmus\Psg28, Mmus\Psg18, Mmus\Psg26, Mmus\Psg16, Mmus\Ceacam14, Mmus\Psg17, Mmus\Psg21, Mmus\Hepacam, Mmus\Ceacam13, Mmus\Gm5155, Mmus\Ceacam5, Mmus\Ceacam12, Mmus\Ceacam9, Mmus\Psg25, Mmus\Psg29, Mmus\Psg22" "Hsap\SIRPG, Hsap\HEPACAM2, Hsap\CD276, Hsap\SIRPB1, Hsap\SIRPA, Hsap\CRTAM" " embryonic stage | stage >=15 , embryonic stage | stage 9-12 , embryonic stage | stage 9 " " larval muscle system

, embryonic peripheral nervous system

, sensory mother cell

" FBgn0062526 l(3)88EFf lethal (3) 88EFf http://flybase.org/reports/FBgn0062526 gene - - - l(3)88EFf - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005056 fs(2)OW102 female sterile (2) OW102 http://flybase.org/reports/FBgn0005056 - gene - - - fs(2)OW102 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266261 CG44956 - http://flybase.org/reports/FBgn0266261 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44956 - CG44956 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044073 E(rst)J25 E(rst)J25 http://flybase.org/reports/FBgn0044073 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "J25, E(rst)J25" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267084 CR45528 - http://flybase.org/reports/FBgn0267084 non_protein_coding_gene - - - CR45528 - CR45528 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034425 CG11906 - http://flybase.org/reports/FBgn0034425 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "11906, CG11906" IPR013087:Zinc finger C2H2-type CG11906 11-Aug-17 DroID_v2017_08 "Drer\aga, Drer\im:7147486, Drer\zgc:153169, Drer\znf142" Scer\RME1 - Xtro\aga "Mmus\Aga, Mmus\Zfp574, Mmus\Zfp142" "Hsap\ZNF142, Hsap\AGA, Hsap\ZNF33A, Hsap\ZNF574" "viable,fertile" FBgn0266513 s-523.2 - http://flybase.org/reports/FBgn0266513 gene - - - s-523.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034950 Pask PAS kinase http://flybase.org/reports/FBgn0034950 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:17270" regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:17270 protein phosphorylation ; GO:0006468 | non-traceable author statement nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:17270 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:17270 "pask, Pask, CG3105" "IPR000014:PAS domain, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG3105 11-Aug-17 DroID_v2017_08 "Drer\pask, Drer\pim3, Drer\LOC108179363, Drer\zgc:66101" "Scer\PSK2, Scer\PSK1" "Cele\kin-33, Cele\prk-2" Xtro\pim3 "Mmus\Sik3, Mmus\Pask, Mmus\Pim1, Mmus\Pim3, Mmus\Pim2" "Hsap\PIM3, Hsap\PASK, Hsap\PIM2, Hsap\SIK3" viable FBgn0262752 Mst77Y-3Psi Male-specific pseudogene 77Y 3 http://flybase.org/reports/FBgn0262752 pseudogene_attribute - - - Mst77Y-3Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019733 l(1)A13 lethal (1) A13 http://flybase.org/reports/FBgn0019733 - gene - - - l(1)A13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010622 DCTN3-p24 "Dynactin 3, p24 subunit" http://flybase.org/reports/FBgn0010622 FBgn0034813 protein_coding_gene - microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype dynactin complex ; GO:0005869 | inferred from sequence or structural similarity with MGI:MGI:1859251 dynactin complex ; GO:0005869 | inferred from sequence or structural similarity "CG9893, l(2)06496, p24, l(2)06 496, p22/p24, DCTN3, DCTN3-p24, P24" IPR009991:Dynactin subunit p22 CG9893 11-Aug-17 DroID_v2017_08 Drer\dctn3 - - - Mmus\Dctn3 Hsap\DCTN3 "lethal,recessive" FBgn0060461 l(3)S115510b lethal (3) S115510b http://flybase.org/reports/FBgn0060461 gene - - - "1155/10, l(3)S115510b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052398 CG32398 - http://flybase.org/reports/FBgn0052398 protein_coding_gene - - - CG32398 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040329 EY3-2 EY3-2 http://flybase.org/reports/FBgn0040329 gene - - - EY3-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000124 Ars-region2 Autonomous replicating sequence region 2 http://flybase.org/reports/FBgn0000124 - region - - - "DmARS-2, Ars-region2, Ars2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034162 CG6426 - http://flybase.org/reports/FBgn0034162 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR008597 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "l(2)k04810, n(2)k04810, BcDNA:RH01665, CG6426" IPR008597:Destabilase CG6426 11-Aug-17 DroID_v2017_08 - - "Cele\ilys-3, Cele\ilys-4, Cele\ilys-6, Cele\ilys-1, Cele\ilys-5, Cele\ilys-2" - - - "viable,fertile" FBgn0036469 CG18649 - http://flybase.org/reports/FBgn0036469 protein_coding_gene - - - "BcDNA:RE73239, CG18649" - CG18649 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC10334 IK 1.514783743 1.90338617 0.33761691 -0.227576919 -0.502353603 1.602338918 FBgn0035299 CG11815 - http://flybase.org/reports/FBgn0035299 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial respiratory chain complex I ; GO:0005747 | inferred from electronic annotation with InterPro:IPR026193 cellular_component ; GO:0005575 | no biological data available CG11815 IPR026193:NADH-ubiquinone oxidoreductase flavoprotein 3 CG11815 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038608 WRNexo WRN exonuclease http://flybase.org/reports/FBgn0038608 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002562, InterPro:IPR012337 single-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008310 | inferred from direct assay double-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008311 | inferred from direct assay 3'-5' exonuclease activity ; GO:0008408 | inferred from sequence or structural similarity with HGNC:12791 3'-5' exonuclease activity ; GO:0008408 | inferred from mutant phenotype" "replication fork protection ; GO:0048478 | inferred from genetic interaction with spn-A negative regulation of mitotic recombination ; GO:0045950 | inferred from mutant phenotype DNA catabolic process, exonucleolytic ; GO:0000738 | inferred from direct assay DNA catabolic process, exonucleolytic ; GO:0000738 | inferred by curator from GO:0008408" nucleus ; GO:0005634 | inferred from direct assay "WRNexo, CG7670, DmWRNexo" "IPR002562:3'-5' exonuclease domain, IPR012337:Ribonuclease H-like domain" CG7670 11-Aug-17 DroID_v2017_08 "Drer\wrn, Drer\exd2" - Cele\wrn-1 "Xtro\wrn, Xtro\exd2" "Mmus\Exd2, Mmus\Wrn" "Hsap\WRN, Hsap\EXD2" "viable,fertile,female sterile,male fertile,chemical sensitive,partially lethal - majority die,some die during pupal stage" DRSC16278 K 0.267051824 0.122949397 0.463713755 0.412671518 1.965578096 -1.673582142 FBgn0000935 fs(2)A5 female sterile (2) A5 http://flybase.org/reports/FBgn0000935 - gene - - - fs(2)A5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0053983 obst-H obstructor-H http://flybase.org/reports/FBgn0053983 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG17014, CG7973, obst-H, CG7973(short), CG33983, FBgn0036507" IPR002557:Chitin binding domain CG33983 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\cpg-2, Cele\C39D10.7, Cele\cpg-1" - - - viable FBgn0065182 l(3)SH001 lethal (3) SH001 http://flybase.org/reports/FBgn0065182 gene - - - "l(3)SH001, l(2)SH3 001" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266589 CR45114 - http://flybase.org/reports/FBgn0266589 non_protein_coding_gene - - - "CR45114, lincRNA.452" - CR45114 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022075 l(2)k07713 lethal (2) k07713 http://flybase.org/reports/FBgn0022075 - gene - - - l(2)k07713 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021917 l(2)k11325 lethal (2) k11325 http://flybase.org/reports/FBgn0021917 - gene - - - l(2)k11325 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069171 mcl(3)Z0589 mcl(3)Z0589 http://flybase.org/reports/FBgn0069171 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z0589 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0016861 l(1)N9 lethal (1) N9 http://flybase.org/reports/FBgn0016861 - gene - - - "l(1)N9, N9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020774 vi vena interrupta http://flybase.org/reports/FBgn0020774 - gene - - - vi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265888 CR44677 - http://flybase.org/reports/FBgn0265888 non_protein_coding_gene - - - "CR44677, lincRNA.626" - CR44677 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067045 U12 U12 http://flybase.org/reports/FBgn0067045 gene - - - U12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" chaeta FBgn0004550 l(4)102CDv lethal (4) 102CDv http://flybase.org/reports/FBgn0004550 - gene - - - "l(4)37, l(4)102CDv" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262709 ifm(2)RS2 - http://flybase.org/reports/FBgn0262709 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0043375 EP1216b EP1216b http://flybase.org/reports/FBgn0043375 gene - - - EP1216b - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "macrochaeta,ectopic,trichogen cell,tormogen cell" FBgn0067661 pup poulpe http://flybase.org/reports/FBgn0067661 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available pup - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,germline clone" FBgn0058244 CG40244 - http://flybase.org/reports/FBgn0058244 protein_coding_gene - - - CG40244 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21814 IEK 5.560697221 -2.22747849 10.01167853 -0.067034215 -7.683167223 -5.327016062 FBgn0051767 CR31767 - http://flybase.org/reports/FBgn0051767 non_protein_coding_gene - - - CR31767 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060725 l(3)S068016 lethal (3) S068016 http://flybase.org/reports/FBgn0060725 gene - - - "0680/16, l(3)S068016" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040493 grsm granny smith http://flybase.org/reports/FBgn0040493 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "BcDNA:LD41548, CG7340, l(3)c00064, grsm, granny-smith, granny smith" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG7340 11-Aug-17 DroID_v2017_08 "Drer\lap3, Drer\zgc:152830, Drer\npepl1" - "Cele\lap-2, Cele\lap-1" "Xtro\lap3, Xtro\npepl1" "Mmus\Lap3, Mmus\Npepl1" "Hsap\LAP3, Hsap\NPEPL1" "lethal,recessive,viable,fertile" FBgn0036159 CG7557 - http://flybase.org/reports/FBgn0036159 protein_coding_gene - - - "anon-WO0140519.44, CG7557" IPR027417:P-loop containing nucleoside triphosphate hydrolase CG7557 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004069 fs(2)mel3 female sterile (2) maternal effect lethal 3 http://flybase.org/reports/FBgn0004069 - gene - - - "mel 3, fs(2)mel3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "chorion | maternal effect,dorsal appendage,maternal effect,egg,pole cell,amnioproctodeal invagination,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,cephalic furrow,abdominal segment 2,abdominal segment 3,abdominal segment 4,embryonic/larval posterior spiracle,filzkorper,embryonic head" FBgn0014924 anon-72ABh anon-72ABh http://flybase.org/reports/FBgn0014924 - gene - - - anon-72ABh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004441 prd8 paired-like 8 http://flybase.org/reports/FBgn0004441 - gene - - - prd8 - - 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage , embryonic stage | <8-12 hr " FBgn0033677 CG8321 - http://flybase.org/reports/FBgn0033677 protein_coding_gene - - - CG8321 IPR029383:ADP-ribosylation factor-like protein 6-interacting protein 6 CG8321 11-Aug-17 DroID_v2017_08 Drer\arl6ip6 - - - Mmus\Arl6ip6 Hsap\ARL6IP6 "learning defective,viable" FBgn0039038 CG6688 - http://flybase.org/reports/FBgn0039038 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 multicellular organism development ; GO:0007275 | inferred from electronic annotation with InterPro:IPR004162 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR004162 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR004162 CG6688 "IPR001478:PDZ domain, IPR001841:Zinc finger, RING-type, IPR004162:E3 ubiquitin-protein ligase SIN-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6688 11-Aug-17 DroID_v2017_08 "Drer\cyhr1, Drer\grip2b, Drer\il16, Drer\dlg5a, Drer\grip1, Drer\slc9a3r1, Drer\grid2ipa, Drer\siah2l, Drer\lnx1, Drer\pdzd7b, Drer\si:dkey-92i15.4, Drer\pard3bb, Drer\siah1, Drer\inadl" - Cele\siah-1 "Xtro\grip2, Xtro\siah1, Xtro\dlg5, Xtro\siah2, Xtro\lnx1, Xtro\grid2ip, Xtro\grip1" "Mmus\Mpdz, Mmus\Pdzd11, Mmus\Ush1c, Mmus\Grip1, Mmus\Pdzd2, Mmus\Patj, Mmus\Siah1a, Mmus\Grasp, Mmus\6330408A02Rik, Mmus\Cyhr1, Mmus\Slc9a3r2, Mmus\Il16, Mmus\Grid2ip, Mmus\Siah3, Mmus\Grip2, Mmus\Siah1b, Mmus\Lnx1, Mmus\Pdzph1, Mmus\Siah2, Mmus\Dlg5" "Hsap\GRID2IP, Hsap\SIAH3, Hsap\FRMPD2, Hsap\C19orf68, Hsap\PARD3B, Hsap\IL16, Hsap\PATJ, Hsap\SLC9A3R2, Hsap\USH1C, Hsap\CYHR1, Hsap\PDZD2, Hsap\GRASP, Hsap\MPDZ, Hsap\SIAH2, Hsap\LNX1, Hsap\SIAH1, Hsap\GRIP1, Hsap\DLG5" "viable,fertile" FBgn0065073 snoRNA:229 snoRNA:229 http://flybase.org/reports/FBgn0065073 snoRNA_gene - - - "Dm-229, snoR229, CR33684, snoRNA:229, DmOr_cd3, SnoR229, chr2R:18581419..18581570" - CR33684 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029898 CG14439 - http://flybase.org/reports/FBgn0029898 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG14439 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG14439 11-Aug-17 DroID_v2017_08 "Drer\spns2, Drer\spns3, Drer\spns1" - - Xtro\spns1 "Mmus\Spns1, Mmus\Spns3, Mmus\Spns2" "Hsap\SPNS1, Hsap\SPNS2, Hsap\SPNS3" "viable,fertile" FBgn0069416 JJF144 JJF144 http://flybase.org/reports/FBgn0069416 gene - - - JJF144 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0260005 wtrw water witch http://flybase.org/reports/FBgn0260005 protein_coding_gene cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with pyx calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from sequence or structural similarity with pyx calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity response to humidity ; GO:0009270 | inferred from mutant phenotype cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with pyx "CG17817, wtrw, CG31284, 153412_at, CT29234, CG10409, Wtrw, dTRPA3, trpA3" "IPR002110:Ankyrin repeat, IPR005821:Ion transport domain, IPR020683:Ankyrin repeat-containing domain" CG31284 11-Aug-17 DroID_v2017_08 "Drer\trpa1a, Drer\trpa1b" - "Cele\osm-9, Cele\trpa-1" Xtro\trpa1 "Mmus\Trpv1, Mmus\Trpa1" "Hsap\TRPA1, Hsap\TRPV1" FBgn0051952 CG31952 - http://flybase.org/reports/FBgn0051952 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15413, BcDNA:AT14709, CG31952" - CG31952 11-Aug-17 DroID_v2017_08 - - - - Mmus\Basp1 - "viable,visible" "chaeta,supernumerary" DRSC21997 IK -1.550360148 0.05717731 -1.285798533 -1.056348261 0.418455833 1.683162186 FBgn0061005 l(3)S026437 lethal (3) S026437 http://flybase.org/reports/FBgn0061005 gene - - - "0264/37, l(3)S026437" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266145 CR44851 - http://flybase.org/reports/FBgn0266145 non_protein_coding_gene - - - CR44851 - CR44851 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000853 fs(1)M43 female sterile (1) M43 http://flybase.org/reports/FBgn0000853 - gene - - - fs(1)M43 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,lethal - all die before end of embryonic stage,maternal effect,heat sensitive,some die during embryonic stage" "egg,maternal effect" FBgn0032303 CG6508 - http://flybase.org/reports/FBgn0032303 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 - CG6508 "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG6508 11-Aug-17 DroID_v2017_08 "Drer\zgc:103530, Drer\ren, Drer\nots, Drer\ctsd, Drer\zgc:63831" "Scer\MKC7, Scer\YGL258W-A, Scer\YPS6, Scer\YPS5, Scer\YPS1, Scer\YPS3, Scer\BAR1, Scer\YPS7, Scer\PEP4" "Cele\asp-10, Cele\asp-17, Cele\asp-13, Cele\asp-9, Cele\asp-8, Cele\asp-4, Cele\asp-2, Cele\asp-6, Cele\asp-15, Cele\asp-7, Cele\asp-16, Cele\asp-18, Cele\asp-19, Cele\asp-5, Cele\asp-3, Cele\asp-12, Cele\asp-1" "Xtro\pgc, Xtro\ctse, Xtro\pga4, Xtro\ctsd, Xtro\ren, Xtro\bace1, Xtro\napsa, Xtro\LOC496913, Xtro\bace2" "Mmus\Pgc, Mmus\Ren1, Mmus\Napsa, Mmus\Ctse, Mmus\Cym, Mmus\Ctsd, Mmus\Pga5, Mmus\Bace1, Mmus\Bace2" "Hsap\BACE1, Hsap\PGA3, Hsap\CTSE, Hsap\CTSD, Hsap\PGA5, Hsap\PGC, Hsap\BACE2, Hsap\PGA4, Hsap\NAPSA, Hsap\REN" viable FBgn0030582 CG14411 - http://flybase.org/reports/FBgn0030582 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from sequence model phosphatidylinositol-3-phosphatase activity ; GO:0004438 | inferred from sequence or structural similarity with SGD:S000003871 phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from sequence or structural similarity with SGD:S000003871 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003871 CG14411 "IPR030564:Myotubularin family, IPR011993:PH domain-like, IPR029021:Protein-tyrosine phosphatase-like, IPR010569:Myotubularin-like phosphatase domain, IPR022587:Myotubularin-related 12-like C-terminal domain" CG14411 11-Aug-17 DroID_v2017_08 "Drer\mtmr8, Drer\sbf1, Drer\mtmr2, Drer\mtmr6, Drer\mtmr12, Drer\zgc:154055, Drer\mtmr11, Drer\mtmr7a, Drer\sbf2, Drer\mtmr7b, Drer\mtmr1b, Drer\mtmr10, Drer\mtmr9, Drer\mtmr1a" Scer\YMR1 "Cele\mtm-5, Cele\mtm-3, Cele\mtm-1, Cele\Y48G1C.10" "Xtro\mtmr10, Xtro\mtmr6, Xtro\mtm1, Xtro\mtmr1, Xtro\asb12.2, Xtro\mtmr2, Xtro\mtmr7, Xtro\mtmr12, Xtro\LOC100216114, Xtro\mtmr9" "Mmus\Mtm1, Mmus\Sbf2, Mmus\Mtmr2, Mmus\Mtmr12, Mmus\Mtmr7, Mmus\Mtmr1, Mmus\Mtmr10, Mmus\Mtmr6, Mmus\Mtmr9, Mmus\Mtmr11, Mmus\Sbf1" "Hsap\MTMR1, Hsap\MTM1, Hsap\SBF2, Hsap\MTMR9, Hsap\MTMR10, Hsap\MTMR7, Hsap\SBF1, Hsap\MTMR2, Hsap\MTMR6, Hsap\MTMR8, Hsap\MTMR11, Hsap\MTMR12" viable FBgn0023202 Hci Hci http://flybase.org/reports/FBgn0023202 - gene - - - "DHCI, Hci" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028229 l(3)S004624 lethal (3) S004624 http://flybase.org/reports/FBgn0028229 gene - - - "0245/33, 0475/22, l(3)S024533a, l(3)S047522, l(3)S004624" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0264276 Su(Mir)2 - http://flybase.org/reports/FBgn0264276 gene - - - Su(Mir)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile,lethal" FBgn0267775 CR46106 - http://flybase.org/reports/FBgn0267775 non_protein_coding_gene - - - CR46106 - CR46106 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069106 mus318 mutagen-sensitive 318 http://flybase.org/reports/FBgn0069106 gene - - - mus318 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0060570 l(3)S096003b lethal (3) S096003b http://flybase.org/reports/FBgn0060570 gene - - - "0960/03, l(3)S096003b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0065352 l(2)SH1797 lethal (2) SH1797 http://flybase.org/reports/FBgn0065352 gene - - - "l(2)SH1797, l(2)SH2 1797" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036390 CG13738 - http://flybase.org/reports/FBgn0036390 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE61257, CG13738" - CG13738 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC10065 IE 0.413682796 -2.651382887 0.34192245 -1.669579992 -0.781042733 0.202180698 FBgn0263968 nonC no-on-and-no-off transient C http://flybase.org/reports/FBgn0263968 protein_coding_gene protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 protein kinase activity ; GO:0004672 | non-traceable author statement "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from direct assay RNA interference ; GO:0016246 | NOT inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 gene silencing by miRNA ; GO:0035195 | NOT inferred from mutant phenotype response to stress ; GO:0006950 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 phosphorylation ; GO:0016310 | non-traceable author statement nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | NOT inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from direct assay synapse organization ; GO:0050808 | inferred from direct assay synaptic vesicle transport ; GO:0048489 | inferred from direct assay peptidyl-serine phosphorylation ; GO:0018105 | inferred from sequence or structural similarity with UniProtKB:Q96Q15" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 "nonC, smg1, CG32743, rst(1a)cyr, CG4555, CG4549, SMG1, clone 1.24, anon-EST:Liang-1.24, anon-WO0170980.133, Smg1, Smg, dSmg1" "IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR003152:FATC domain, IPR011009:Protein kinase-like domain, IPR014009:PIK-related kinase, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR031559:Serine/threonine-protein kinase SMG1" CG32743 11-Aug-17 DroID_v2017_08 "Drer\smg1, Drer\prkdc" "Scer\TOR1, Scer\TOR2" Cele\smg-1 "Xtro\mtor, Xtro\smg1, Xtro\prkdc" "Mmus\Prkdc, Mmus\Smg1, Mmus\Mtor" "Hsap\BOLA2-SMG1P6, Hsap\BOLA2B, Hsap\BOLA2, Hsap\PRKDC, Hsap\MTOR, Hsap\SMG1" FBgn0061512 frogger\polyprotein frogger element polyprotein http://flybase.org/reports/FBgn0061512 transposable_element_gene - - - frogger\polyprotein "IPR013103:Reverse transcriptase, RNA-dependent DNA polymerase" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042110 CG18765 - http://flybase.org/reports/FBgn0042110 protein_coding_gene - - - CG18765 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG18765 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.10, Cele\F59B1.8, Cele\nhr-246, Cele\C29F7.2" - - - viable FBgn0086038 snoRNA:Me28S-C1237 - http://flybase.org/reports/FBgn0086038 snoRNA_gene - - - "snoRNA:Me28S-C1237, Me28S-Cm1237, CR34667" - CR34667 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259848 Su(Ste):CR42417 Su(Ste):CR42417 http://flybase.org/reports/FBgn0259848 non_protein_coding_gene - - - "Su(Ste):CR42417, CR42417" - CR42417 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029050 l(1)G0462 lethal (1) G0462 http://flybase.org/reports/FBgn0029050 gene - - - l(1)G0462 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261565 Lmpt Limpet http://flybase.org/reports/FBgn0261565 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781, InterPro:IPR010442" defense response to fungus ; GO:0050832 | inferred from mutant phenotype - "Lmpt, CG42679, CG11915, CG11914, CG9959, CG11916, CG32171, BcDNA:RE37250, lmpt, CG33256" "IPR001781:Zinc finger, LIM-type, IPR010442:PET domain" CG42679 11-Aug-17 DroID_v2017_08 "Drer\leo1, Drer\fhl2b, Drer\rp1, Drer\fhl2a" Scer\YFR016C Cele\lim-9 "Xtro\leo1, Xtro\fhl2" "Mmus\Fhl2, Mmus\Dmp1, Mmus\Rp1, Mmus\Leo1, Mmus\Ibsp" "Hsap\DMP1, Hsap\FHL2, Hsap\IBSP, Hsap\LEO1, Hsap\RP1" DRSC22921 I 1.762778912 -0.415694471 -0.52595675 -0.322251979 0.200986473 -0.647340685 FBgn0014016 Rbp13 RNA-binding protein 13 http://flybase.org/reports/FBgn0014016 - gene - - - "RBP, Rbp, Rbp13" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004554 Edg91 Ecdysone-dependent gene 91 http://flybase.org/reports/FBgn0004554 - protein_coding_gene structural constituent of pupal chitin-based cuticle ; GO:0008011 | traceable author statement - - "EDG-91, EDG91, CG7539, Edg91" - CG7539 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013613 l(3)L1042 lethal (3) L1042 http://flybase.org/reports/FBgn0013613 - gene - - - l(3)L1042 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060781 l(3)S060402 lethal (3) S060402 http://flybase.org/reports/FBgn0060781 gene - - - "0604/02, l(3)S060402" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0069985 BG02201 BG02201 http://flybase.org/reports/FBgn0069985 gene - - - BG02201 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0082576 Curled_like Curled like http://flybase.org/reports/FBgn0082576 gene - - - "Curled_like, Cul" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" wing FBgn0263465 snoRNA:kis-a - http://flybase.org/reports/FBgn0263465 snoRNA_gene - - - "snoRNA:kis-a, snoCD_02" - CR43580 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266020 CR44785 - http://flybase.org/reports/FBgn0266020 non_protein_coding_gene - - - "CR44785, lincRNA.210" - CR44785 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032448 CG5781 - http://flybase.org/reports/FBgn0032448 protein_coding_gene - - - CG5781 - CG5781 11-Aug-17 DroID_v2017_08 - - Cele\ZK1053.3 - - - viable FBgn0032424 CG17010 - http://flybase.org/reports/FBgn0032424 protein_coding_gene ribokinase activity ; GO:0004747 | inferred from sequence or structural similarity with SGD:S000000632 carbohydrate kinase activity ; GO:0019200 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 D-ribose metabolic process ; GO:0006014 | inferred from sequence or structural similarity with SGD:S000000632 carbohydrate phosphorylation ; GO:0046835 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000632 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000632 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 CG17010 "IPR002139:Ribokinase/fructokinase, IPR011611:Carbohydrate kinase PfkB, IPR029056:Ribokinase-like, IPR011877:Ribokinase" CG17010 11-Aug-17 DroID_v2017_08 Drer\rbks Scer\RBK1 Cele\F07A11.5 Xtro\rbks Mmus\Rbks Hsap\RBKS FBgn0000222 brw broader wing http://flybase.org/reports/FBgn0000222 - gene - - - brw - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,poor,male sterile,visible,recessive" wing FBgn0010890 l(3)06465 lethal (3) 06465 http://flybase.org/reports/FBgn0010890 - gene - - - l(3)06465 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003653 svs shortened veins http://flybase.org/reports/FBgn0003653 - gene - - - "shv, svs" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male fertile,viable,male,reduced,visible" "wing,wing vein,wing vein L4,eye,posterior crossvein" FBgn0029170 TwdlT TweedleT http://flybase.org/reports/FBgn0029170 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "CG5812, GCR(ich), TwdlT" IPR004145:Domain of unknown function DUF243 CG5812 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014219 l(2)31Db lethal (2) 31Db http://flybase.org/reports/FBgn0014219 - gene - - - l(2)31Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033330 CG8746 - http://flybase.org/reports/FBgn0033330 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8746 - CG8746 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004049 yrt yurt http://flybase.org/reports/FBgn0004049 "FBgn0000466, FBgn0002363, FBgn0038155" protein_coding_gene cytoskeletal protein binding ; GO:0008092 | inferred from electronic annotation with InterPro:IPR000798 structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity eye photoreceptor cell development ; GO:0042462 | inferred from mutant phenotype establishment or maintenance of apical/basal cell polarity ; GO:0035088 | inferred from mutant phenotype amnioserosa maintenance ; GO:0046665 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from genetic interaction with aPKC actomyosin structure organization ; GO:0031032 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 head involution ; GO:0008258 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype extrinsic component of membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000798 zonula adherens ; GO:0005915 | inferred from direct assay cytoskeleton ; GO:0005856 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 septate junction ; GO:0005918 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "yrt, l(3)m112, CG9764, Nbl4, l(3)87Ek, m112, l(3)E19, dlhB, Yrt" "IPR000299:FERM domain, IPR000798:Ezrin/radixin/moesin-like, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR014847:FERM adjacent (FA), IPR018980:FERM, C-terminal PH-like domain, IPR018979:FERM, N-terminal, IPR019747:FERM conserved site, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain" CG9764 11-Aug-17 DroID_v2017_08 "Drer\epb41l4b, Drer\epb41l5" - Cele\frm-2 Xtro\epb41l5 "Mmus\Epb41l5, Mmus\Epb41l4b" "Hsap\EPB41L4B, Hsap\EPB41L5" "lethal,cell polarity defective,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable" "macrochaeta,ommatidium,epidermis,germline clone,trachea,embryonic/first instar larval cuticle,eye photoreceptor cell stalk,eye photoreceptor cell,conditional,rhabdomere of eye photoreceptor cell,adherens junction,embryonic head,amnioserosa,embryo,dorsal,posterior,dorsal ridge,embryonic/larval cuticle" FBgn0259369 EP-596 - http://flybase.org/reports/FBgn0259369 gene - - - EP-596 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing,wing margin" FBgn0036852 CG14083 - http://flybase.org/reports/FBgn0036852 protein_coding_gene - - - CG14083 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260327 GSd031 - http://flybase.org/reports/FBgn0260327 gene - - - GSd031 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0085606 CG41310 - http://flybase.org/reports/FBgn0085606 protein_coding_gene - - - CG41310 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019797 l(1)08 lethal (1) 08 http://flybase.org/reports/FBgn0019797 - gene - - - l(1)08 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0000700 fltF flight defective F http://flybase.org/reports/FBgn0000700 - gene - - - fltF - - 11-Aug-17 DroID_v2017_08 - - - - - - "jumping defective,flight defective" FBgn0038858 CG5793 - http://flybase.org/reports/FBgn0038858 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011234 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR011234 - "CG5793, FBgn0038858" "IPR011234:Fumarylacetoacetase, C-terminal-related" CG5793 11-Aug-17 DroID_v2017_08 "Drer\fahd1, Drer\fahd2a" Scer\FMP41 Cele\fahd-1 "Xtro\fahd2a, Xtro\fahd1" "Mmus\Fahd1, Mmus\Fahd2a" "Hsap\FAHD1, Hsap\FAHD2B, Hsap\FAHD2A" viable FBgn0262875 CG43230 - http://flybase.org/reports/FBgn0262875 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43230 - CG43230 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028173 l(3)S026430 lethal (3) S026430 http://flybase.org/reports/FBgn0028173 gene - - - "0264/30, l(3)S026430" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0265146 CG44215 - http://flybase.org/reports/FBgn0265146 protein_coding_gene - - - "CR44215, CG44215" - CG44215 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014242 l(2)32Ac lethal (2) 32Ac http://flybase.org/reports/FBgn0014242 - gene - - - l(2)32Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002221 l(3)68Aa lethal (3) 68Aa http://flybase.org/reports/FBgn0002221 - gene - - - "l(3)C288, l(3)68Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage" macrochaeta FBgn0267193 CR45633 - http://flybase.org/reports/FBgn0267193 non_protein_coding_gene - - - CR45633 - CR45633 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037852 Tpc1 Thiamine pyrophosphate carrier protein 1 http://flybase.org/reports/FBgn0037852 protein_coding_gene thiamine pyrophosphate-transporting ATPase activity ; GO:0015619 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 mitochondrial transport ; GO:0006839 | inferred from genetic interaction with SGD:S000003328 thiamine pyrophosphate transport ; GO:0030974 | inferred from direct assay integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000756668 "CG6608, Tpc1, DmTpc1, Q9VGU9" "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG6608 11-Aug-17 DroID_v2017_08 "Drer\slc25a43, Drer\slc25a19, Drer\slc25a16" "Scer\YPR011C, Scer\LEU5, Scer\TPC1" "Cele\C47E12.2, Cele\F47B8.10, Cele\hpo-12" "Xtro\slc25a43, Xtro\slc25a19, Xtro\slc25a42" "Mmus\Slc25a43, Mmus\Slc25a42, Mmus\Slc25a19, Mmus\Slc25a16" "Hsap\SLC25A43, Hsap\SLC25A16, Hsap\SLC25A42, Hsap\SLC25A19" "visible,viable" wing DRSC15614 I -0.252611386 -2.59170152 -0.350131061 -1.220479227 0.552369677 0.253307087 FBgn0035179 CG12038 - http://flybase.org/reports/FBgn0035179 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12038 "IPR029244:FAM69, N-terminal, IPR022049:FAM69, protein-kinase domain" CG12038 11-Aug-17 DroID_v2017_08 "Drer\fam69aa, Drer\fam69b, Drer\fam69c, Drer\fam69ab" - Cele\C53D5.1 "Xtro\fam69a, Xtro\fam69b, Xtro\fam69c" "Mmus\Fam69a, Mmus\Fam69c, Mmus\Fam69b" "Hsap\FAM69C, Hsap\FAM69A, Hsap\FAM69B" FBgn0065278 l(2)SH2044 lethal (2) SH2044 http://flybase.org/reports/FBgn0065278 gene - - - "l(2)SH2044, l(2)SH2 2044" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020261 pcm pacman http://flybase.org/reports/FBgn0020261 - protein_coding_gene exonuclease activity ; GO:0004527 | inferred from electronic annotation with InterPro:IPR004859 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004859 "nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' ; GO:0034428 | inferred from mutant phenotype regulation of cytoplasmic mRNA processing body assembly ; GO:0010603 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern nuclear-transcribed mRNA catabolic process, non-stop decay ; GO:0070481 | inferred from mutant phenotype inferred from genetic interaction with pix" cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay "XRN1, CG3291, pcm, XRN1/pcm, Xrn1p, Pcm, Xrn1, DmXrn1" "IPR004859:Putative 5-3 exonuclease, IPR027073:5'-3' exoribonuclease, IPR029060:PIN domain-like" CG3291 11-Aug-17 DroID_v2017_08 "Drer\xrn2, Drer\xrn1" "Scer\RAT1, Scer\XRN1" "Cele\xrn-1, Cele\xrn-2" "Xtro\xrn2, Xtro\xrn1" "Mmus\Xrn2, Mmus\Xrn1" "Hsap\XRN2, Hsap\XRN1" " adult stage && oogenesis stage , adult stage | male , adult stage | female , embryonic stage | 0-8hr , embryonic stage | stage 1-7 " " nurse cell

, oocyte

,

ubiquitous " "visible,partially lethal - majority die,some die during pupal stage,viable,wound healing defective,fertile,reduced,female semi-sterile,recessive,cold sensitive,partially lethal - majority live" "mesothoracic tergum,testis,spermatozoon,egg chamber,wing,cold sensitive,posterior wing margin,metathoracic femur,cytoplasmic mRNA processing body | cold sensitive,pupal thorax,embryonic/first instar larval cuticle,cytoplasmic mRNA processing body | cold sensitiveJA27)" FBgn0028700 RfC38 Replication factor C 38kD subunit http://flybase.org/reports/FBgn0028700 protein_coding_gene DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000186208 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from sequence or structural similarity with SGD:S000000291 leading strand elongation ; GO:0006272 | inferred from sequence or structural similarity with SGD:S000000291 sister chromatid cohesion ; GO:0007062 | inferred from sequence or structural similarity with SGD:S000000291 neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 microtubule associated complex ; GO:0005875 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from sequence or structural similarity with SGD:S000000291 Elg1 RFC-like complex ; GO:0031391 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 "l(2)rfc38, l(2)k13807, n(2)k13807, Rfc38, CG6258, BcDNA:LD06837, RfC38, DmRFC5" "IPR013748:Replication factor C, C-terminal, IPR003593:AAA+ ATPase domain, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG6258 11-Aug-17 DroID_v2017_08 Drer\rfc3 Scer\RFC5 Cele\rfc-3 Xtro\rfc3 Mmus\Rfc3 Hsap\RFC3 "lethal,recessive,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0065814 l(2)SH0381 lethal (2) SH0381 http://flybase.org/reports/FBgn0065814 gene - - - "l(2)SH0381, l(2)SH2 0381" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259965 Sfp35C Seminal fluid protein 35C http://flybase.org/reports/FBgn0259965 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp35C, CG42475" - CG42475 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260278 GSd098 - http://flybase.org/reports/FBgn0260278 gene - - - GSd098 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035027 CG3511 - http://flybase.org/reports/FBgn0035027 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 biological_process ; GO:0008150 | no biological data available" catalytic step 2 spliceosome ; GO:0071013 | inferred from sequence or structural similarity with HGNC:28954 CG3511 "IPR001680:WD40 repeat, IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain" CG3511 11-Aug-17 DroID_v2017_08 Drer\ppwd1 "Scer\CPR2, Scer\CPR5" Cele\cyn-15 Xtro\ppwd1 Mmus\Ppwd1 Hsap\PPWD1 "large body,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,visible" mesothoracic tergum FBgn0030870 CG6398 - http://flybase.org/reports/FBgn0030870 protein_coding_gene - establishment of glial blood-brain barrier ; GO:0060857 | NOT inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004031 apical cortex ; GO:0045179 | inferred from direct assay septate junction ; GO:0005918 | inferred from sequence or structural similarity with sinu CG6398 IPR004031:PMP-22/EMP/MP20/Claudin superfamily CG6398 11-Aug-17 DroID_v2017_08 "Drer\cacng7a, Drer\si:ch211-150g13.3, Drer\zgc:194665, Drer\cacng5b, Drer\cacng5a, Drer\tmem178, Drer\tmem178b, Drer\si:ch211-87j1.4" - Cele\F53B3.5 Xtro\cldnd1 "Mmus\Cacng5, Mmus\Cacng7" "Hsap\CACNG7, Hsap\CACNG5, Hsap\CLDND1" viable FBgn0259860 Su(Ste):CR42429 Su(Ste):CR42429 http://flybase.org/reports/FBgn0259860 non_protein_coding_gene - - - "Su(Ste):CR42429, SuSte{}RR42263, CR42429" - CR42429 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263448 CR43471 - http://flybase.org/reports/FBgn0263448 non_protein_coding_gene - - - CR43471 - CR43471 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024629 l(2)k15211 lethal (2) k15211 http://flybase.org/reports/FBgn0024629 - gene - - - "152/11, l(2)k15211" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031601 Dim1 Dim1 http://flybase.org/reports/FBgn0031601 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000006286 spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000248409 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000006286 U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000248409 U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000248409 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "BcDNA:RE13747, U5-15kD, Dim1, CG3058" "IPR004123:Dim1 family, IPR012336:Thioredoxin-like fold" CG3058 11-Aug-17 DroID_v2017_08 "Drer\txnl4b, Drer\txnl4a" Scer\DIB1 Cele\Y54G2A.75 "Xtro\txnl4a, Xtro\txnl4b" "Mmus\Txnl4a, Mmus\Txnl4b" "Hsap\TXNL4A, Hsap\TXNL4B" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" "embryonic/larval neuroblast,ganglion mother cell" FBgn0010324 Fs1 Female-specific 1 http://flybase.org/reports/FBgn0010324 - gene - - - Fs1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043895 im(1)457 im(1)457 http://flybase.org/reports/FBgn0043895 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available im(1)457 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000277 CecA2 Cecropin A2 http://flybase.org/reports/FBgn0000277 - protein_coding_gene - defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay antibacterial humoral response ; GO:0019731 | inferred from expression pattern AND inferred from sequence or structural similarity humoral immune response ; GO:0006959 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CecA2, CecA, Cec, CG1367, cecA2, cecA, cec, crpA2, Cec A2" "IPR020400:Cecropin, diptera, IPR000875:Cecropin" CG1367 11-Aug-17 DroID_v2017_08 - - - - - - " pupal stage , adult stage , larval stage " " adult fat body

, embryonic/larval hemocyte

" viable FBgn0040234 c12.2 c12.2 http://flybase.org/reports/FBgn0040234 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR011704 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12149, c12.2" "IPR002035:von Willebrand factor, type A, IPR003593:AAA+ ATPase domain, IPR011704:ATPase, dynein-related, AAA domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12149 11-Aug-17 DroID_v2017_08 Drer\vwa8 Scer\MDN1 Cele\F11C1.5 "Xtro\vwa8, Xtro\mdn1" "Mmus\Mdn1, Mmus\Vwa8" "Hsap\VWA8, Hsap\MDN1" viable FBgn0266204 CR44899 - http://flybase.org/reports/FBgn0266204 non_protein_coding_gene - - - CR44899 - CR44899 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035883 CG13669 - http://flybase.org/reports/FBgn0035883 protein_coding_gene - - - CG13669 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001235 hth homothorax http://flybase.org/reports/FBgn0001235 "FBgn0010875, FBgn0011583, FBgn0015762, FBgn0016022, FBgn0025968" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40427 transcription factor binding ; GO:0008134 | inferred from physical interaction with exd DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with exd transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from physical interaction with exd transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype enhancer binding ; GO:0035326 | inferred from physical interaction with dpp" "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype salivary gland boundary specification ; GO:0007432 | traceable author statement salivary gland boundary specification ; GO:0007432 | non-traceable author statement compound eye development ; GO:0048749 | inferred from genetic interaction with L peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement brain development ; GO:0007420 | inferred from mutant phenotype protein localization to nucleus ; GO:0034504 | inferred from physical interaction with exd head morphogenesis ; GO:0060323 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype regulation of cell fate specification ; GO:0042659 | inferred from mutant phenotype regulation of neuron differentiation ; GO:0045664 | inferred from mutant phenotype proximal/distal pattern formation ; GO:0009954 | traceable author statement Malpighian tubule development ; GO:0072002 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype protein import into nucleus, translocation ; GO:0000060 | inferred from mutant phenotype specification of animal organ identity ; GO:0010092 | traceable author statement positive regulation of decapentaplegic signaling pathway ; GO:0090098 | inferred from mutant phenotype" transcription factor complex ; GO:0005667 | inferred from physical interaction with abd-A inferred from physical interaction with exd nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "MEIS1, Hth, Dm-HTH, P53, CG17117, dtl, hth2, hth1, 1422/04, 1323/07, anon-EST:Liang-2.13, clone 2.13, l(3)86Ca, l(3)05745, Meis1, hth, HTH, homothorax" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR008422:Homeobox KN domain, IPR032453:Homeobox protein PKNOX/Meis, N-terminal" CG17117 11-Aug-17 DroID_v2017_08 "Drer\irx2a, Drer\meis2b, Drer\pknox1.2, Drer\irx5b, Drer\meis1a, Drer\tgif1, Drer\meis2a, Drer\meis3, Drer\pknox1.1, Drer\irx7, Drer\irx6a, Drer\mkxa, Drer\irx3b, Drer\irx5a, Drer\irx4a, Drer\irx4b, Drer\irx1b, Drer\irx1a, Drer\irx3a, Drer\meis1b, Drer\pknox2" "Scer\TOS8, Scer\HMRA2, Scer\MATALPHA2, Scer\HMLALPHA2, Scer\CUP9" Cele\unc-62 "Xtro\meis1, Xtro\pknox2, Xtro\irx5, Xtro\meis3, Xtro\tgif2, Xtro\mkx, Xtro\meis2, Xtro\irx2, Xtro\irx4, Xtro\irx3, Xtro\irx1, Xtro\tgif1" "Mmus\Pknox2, Mmus\Irx3, Mmus\Meis1, Mmus\Irx4, Mmus\Mkx, Mmus\Meis3, Mmus\Tgif2lx2, Mmus\Tgif1, Mmus\Meis2, Mmus\Tgif2lx1, Mmus\Pknox1, Mmus\Tgif2, Mmus\Irx1, Mmus\Irx5, Mmus\Irx6, Mmus\Irx2" "Hsap\IRX5, Hsap\TGIF2LY, Hsap\IRX1, Hsap\IRX4, Hsap\PKNOX1, Hsap\MEIS1, Hsap\MEIS2, Hsap\IRX3, Hsap\TGIF2LX, Hsap\TGIF2-C20orf24, Hsap\IRX6, Hsap\TGIF1, Hsap\TGIF2, Hsap\MEIS3, Hsap\MKX, Hsap\PKNOX2, Hsap\IRX2" " embryonic stage , larval stage | third instar , larval stage , embryonic stage | mid , embryonic stage | stage 7 , embryonic stage | stage >=15 , embryonic stage | stage >=11 , embryonic stage | stage >=6 , embryonic stage | stage >=13 , embryonic stage | cellular blastoderm , embryonic stage -- adult stage " " embryonic thorax

, embryonic nervous system

, antennal disc

, midgut constriction 1 | posterior to

, ventral thoracic disc

, endoderm | mid

, mesothoracic pleurum | presumptive

, Malpighian tubule

, organism | 10-90% egg length

, gastric caecum | primordium

, embryonic nervous system of thorax

, labral segment

, ectoderm

, peripodial epithelium

, embryonic central nervous system

, wing hinge | presumptive

, visceral mesoderm

, midgut constriction 3 | anterior to

, scutum | presumptive

, dorsal mesothoracic disc

, photoreceptor cell

, embryonic maxillary segment

, eye-antennal disc

, eye disc

, embryonic Malpighian tubule

, embryonic mandibular segment

, ptilinum | presumptive

, head capsule | presumptive

, ocellus | presumptive

" " larval stage | third instar , embryonic stage | stage >=13 , embryonic stage | stage >=11 , embryonic stage | stage >=15 , embryonic stage | stage >=6 , larval stage | second instar , embryonic stage " " ventral thoracic disc

, wing hinge | presumptive

, embryonic central nervous system

, labral segment

, embryonic nervous system of thorax

, dorsal mesothoracic disc

, ectoderm

, embryonic maxillary segment

, ocellus | presumptive

, embryonic Malpighian tubule

, peripodial epithelium

, ptilinum | presumptive

, mesothoracic pleurum | presumptive

, eye disc

, antennal disc

, visceral mesoderm

, embryonic mandibular segment

, head capsule | presumptive

, scutum | presumptive

, photoreceptor cell

, embryonic thorax

" "lethal,recessive,homeotic,partially lethal - majority die,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,viable,visible,somatic clone,cell autonomous,size defective,dominant,male,planar polarity defective,cell non-autonomous,heat sensitive" "lch5 neuron,leg,ectopic,antenna,peripheral nervous system,sense organ & neuron,cephalopharyngeal skeleton,embryonic head,embryonic segment,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,abdominal lateral pentascolopidial chordotonal organ lch5,embryonic epidermis,somatic clone,metatarsus,tarsal segment 2,tarsal segment 3,tarsal segment 4,tarsal segment,pretarsus,mesothoracic tibial spur bristle,mesothoracic tibial apical bristle,prothoracic leg,mesothoracic leg,metathoracic leg,eye disc,embryonic/first instar larval cuticle,denticle belt,female genitalia,clasper,adult head,ventral,eye-antennal disc,antennal segment 2 & leg | somatic clone,antennal segment 3 & leg | somatic clone,eye & adult head | ventral,eye,photoreceptor cell,coxa,femur,tibia,motor neuron,glial cell,longitudinal connective,posterior commissure,embryonic ventral nervous system,cell autonomous,bract,wing margin,posterior,alula,wing sclerite,wing hinge,axillary cord,costal vein,wing vein L3,proximal,wing,double row,sensillum campaniformium of dorsal radius,wing margin bristle,scutellar bristle,wing disc,gena,rostral membrane,maxillary palpus,dorsal,embryonic thorax,abdominal segment 1,trochanter,dch3 neuron,embryonic/larval oenocyte precursor,medulla,transmedullary neuron Tm1,medullary intrinsic neuron Mi1,neuroblast NB6-4 of abdomen,neuroblast NB6-4 of thorax,flight muscle,extracoxal depressor muscle,embryonic brain & axon,adult abdominal segment 4,male,adult abdominal segment 5,ommatidium,eye photoreceptor cell,dorsal margin photoreceptor,somatic clone - Minute background,heat sensitive,second segment of antenna,third segment of antenna,presumptive embryonic/larval peripheral nervous system,embryonic/larval lymph gland,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,embryonic thorax & denticle | ectopic,photoreceptor cell & eye-antennal disc | ventral,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,embryonic abdominal segment 1,prothoracic dorsal triscolopidial chordotonal organ dch3 & neuron,mesothoracic dorsal triscolopidial chordotonal organ dch3 & neuron,metathoracic dorsal triscolopidial chordotonal organ dch3 & neuron,distal,abdominal tergite 2,abdominal tergite 3,abdominal tergite & trichome | male | somatic clone,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,pseudotrachea,arista,sex comb,abdominal tergite 5 & trichome | malepnr-MD237,abdominal tergite 6 & trichome | malepnr-MD237,tergite,dorsal margin photoreceptor cell R8,photoreceptor cell R8,dorsal margin photoreceptor cell R7,ventral thoracic disc,morphogenetic furrow,leg sensillum,leg & trichome | somatic clone,unguis,alula & wing sensillumBx-MS1096,scutum,medial,cell non-autonomous,dorsocentral bristle,microchaeta & scutumMS248,antennal disc,head capsule,abdominal tergite 5,abdominal tergite 6,head,wing blade,haltere,retina,photoreceptor cell R7,abdominal segment 2,abdominal segment,Keilin's organ" FBgn0027635 ms(1)266 ms(1)266 http://flybase.org/reports/FBgn0027635 - gene - - - ms(1)266 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile spermatid & nucleus FBgn0030796 CG4829 - http://flybase.org/reports/FBgn0030796 protein_coding_gene glutathione hydrolase activity ; GO:0036374 | inferred from electronic annotation with InterPro:IPR000101 glutathione catabolic process ; GO:0006751 | inferred from electronic annotation with InterPro:IPR000101 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - CG4829 "IPR000101:Gamma-glutamyltranspeptidase, IPR029055:Nucleophile aminohydrolases, N-terminal" CG4829 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-222h21.12, Drer\si:ch73-59p9.2, Drer\ggt1l2.2, Drer\ggt5a, Drer\ggt5b, Drer\si:ch73-236c18.3, Drer\ggt1a, Drer\ggt1b" Scer\ECM38 "Cele\Y7A9A.1, Cele\Y97E10AR.2, Cele\H14N18.4, Cele\C53D5.5, Cele\T03D8.6, Cele\T19H12.6" "Xtro\ggt7, Xtro\ggt1, Xtro\ggt5" "Mmus\Ggt7, Mmus\Ggt1, Mmus\Ggt5, Mmus\Ggt6" "Hsap\GGT7, Hsap\GGT2, Hsap\GGT5, Hsap\GGTLC1, Hsap\GGTLC2, Hsap\GGT1, Hsap\GGT6" FBgn0086034 snoRNA:Me28S-G2743 - http://flybase.org/reports/FBgn0086034 snoRNA_gene - - - "snoRNA:Me28S-G2743, Me28S-Gm2743, CR34663" - CR34663 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028150 l(3)S044601 lethal (3) S044601 http://flybase.org/reports/FBgn0028150 gene - - - "0446/01, l(3)S044601" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004083 Y-seqs Y-chromosome sequences http://flybase.org/reports/FBgn0004083 FBgn0013400 repeat_region - - - "Y95-2, anon-Y95-2, Y-seqs" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037848 Tsp86D Tetraspanin 86D http://flybase.org/reports/FBgn0037848 protein_coding_gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG4591, Dm.Tsp86D, Tsp86D" "IPR018499:Tetraspanin/Peripherin, IPR018503:Tetraspanin, conserved site, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG4591 11-Aug-17 DroID_v2017_08 "Drer\tspan5a, Drer\tspan33a, Drer\rom1b, Drer\prph2b, Drer\zgc:113223, Drer\LOC799194, Drer\zmp:0000000545, Drer\zgc:110329, Drer\tspan5b, Drer\prph2a, Drer\rom1a, Drer\tspan14, Drer\tspan15, Drer\prph2l, Drer\tspan33b" - "Cele\tsp-12, Cele\tsp-20" "Xtro\prph2, Xtro\LOC100489375, Xtro\tspan5, Xtro\tspan33, Xtro\tspan14, Xtro\tspan17, Xtro\tspan15" "Mmus\Tspan14, Mmus\Tspan5, Mmus\Prph2, Mmus\Tspan15, Mmus\Rom1, Mmus\Tspan17, Mmus\Tspan10, Mmus\Tspan33" "Hsap\TSPAN33, Hsap\TSPAN14, Hsap\PRPH2, Hsap\TSPAN5, Hsap\TSPAN10, Hsap\ROM1, Hsap\TSPAN15, Hsap\TSPAN17" viable "sensory mother cell,somatic clone,supernumerary" FBgn0038838 TotB Turandot B http://flybase.org/reports/FBgn0038838 protein_coding_gene - cellular response to UV ; GO:0034644 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from expression pattern response to heat ; GO:0009408 | inferred from direct assay cellular response to heat ; GO:0034605 | inferred from expression pattern response to UV ; GO:0009411 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence or structural similarity with TotA extracellular region ; GO:0005576 | inferred from sequence model "tot, CG5609, BcDNA:LP06769, TotB, Tot B" IPR010825:Stress-inducible humoral factor Turandot CG5609 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264721 CR43989 - http://flybase.org/reports/FBgn0264721 non_protein_coding_gene - - - CR43989 - CR43989 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010076 Ni-K Nicked of Klein http://flybase.org/reports/FBgn0010076 - gene - - - "Ni-K, Ni" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0084807 1.1.3 1.1.3 http://flybase.org/reports/FBgn0084807 gene - - - 1.1.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0003121 pod podgy http://flybase.org/reports/FBgn0003121 - gene - - - pod - - 11-Aug-17 DroID_v2017_08 - - - - - - mitotic cell cycle defective FBgn0062537 anon-3929 anon-3929 http://flybase.org/reports/FBgn0062537 gene - - - "3929, anon-3929" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052986 CG32986 - http://flybase.org/reports/FBgn0052986 protein_coding_gene - - - "CG15866, CG32986" - CG32986 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02509 K 0.532379035 -0.119388262 -0.003069778 0.695146429 2.088412578 0.367085636 FBgn0069150 mcl(3)Z3401 mcl(3)Z3401 http://flybase.org/reports/FBgn0069150 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3401 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0030899 Hesr HES-related http://flybase.org/reports/FBgn0030899 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003650 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650" - "CG5927, Hesr, Her, bHLHc21" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG5927 11-Aug-17 DroID_v2017_08 "Drer\hey1, Drer\hes2.1, Drer\hey2, Drer\her12, Drer\her4.3, Drer\hes6, Drer\her8.2, Drer\bhlhe41, Drer\her4.2, Drer\her15.1, Drer\her15.2, Drer\LOC100149863, Drer\her4.4, Drer\hes2.2, Drer\her2, Drer\her7, Drer\her6, Drer\her5, Drer\her9, Drer\her11, Drer\helt, Drer\her1, Drer\her8a, Drer\bhlhe40, Drer\her13, Drer\heyl, Drer\her3" Scer\PHO4 "Cele\hlh-25, Cele\hlh-27, Cele\lin-22" "Xtro\hey1, Xtro\hes2, Xtro\hes6.1, Xtro\bhlhe40, Xtro\hes1, Xtro\hes4, Xtro\hey2, Xtro\hes7.1, Xtro\hes7.2, Xtro\bhlhe41" "Mmus\Bhlhe41, Mmus\Hes5, Mmus\Hes2, Mmus\Hey2, Mmus\Heyl, Mmus\Hes6, Mmus\Bhlhe40, Mmus\Helt, Mmus\Hes7, Mmus\Hey1, Mmus\Hes3, Mmus\Hes1" "Hsap\HES4, Hsap\BHLHE41, Hsap\HES5, Hsap\HES1, Hsap\HES3, Hsap\HEY1, Hsap\HES6, Hsap\HEYL, Hsap\BHLHE40, Hsap\HELT, Hsap\HEY2, Hsap\HES7, Hsap\HES2" viable FBgn0033770 wuc Wake-up-call http://flybase.org/reports/FBgn0033770 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with aly inferred from physical interaction with comr inferred from physical interaction with topi male meiosis ; GO:0007140 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype DRM complex ; GO:0070176 | inferred from electronic annotation with InterPro:IPR018737 nuclear chromatin ; GO:0000790 | inferred from direct assay "147114_at, BcDNA:AT27450, wuc, CG12442" IPR018737:Protein LIN52 CG12442 11-Aug-17 DroID_v2017_08 Drer\lin52 - Cele\lin-52 Xtro\lin52 Mmus\Lin52 Hsap\LIN52 viable FBgn0036567 CG13074 - http://flybase.org/reports/FBgn0036567 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG13074 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR007110:Immunoglobulin-like domain" CG13074 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039582 Or98b Odorant receptor 98b http://flybase.org/reports/FBgn0039582 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "98b, CG1867, DOR121, 98C.1, Or98b, Or98bP, or98b" "IPR004117:Olfactory receptor, insect" CG1867 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033817 GstE14 Glutathione S transferase E14 http://flybase.org/reports/FBgn0033817 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay ecdysteroid biosynthetic process ; GO:0045456 | inferred from mutant phenotype glutathione metabolic process ; GO:0006749 | inferred from direct assay cholesterol homeostasis ; GO:0042632 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG4688, GstE14, gste14, GSTE14, nobo" "IPR004045:Glutathione S-transferase, N-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold, IPR004046:Glutathione S-transferase, C-terminal" CG4688 11-Aug-17 DroID_v2017_08 "Drer\gstr, Drer\gstt1b, Drer\gstt1a, Drer\eef1e1, Drer\vars, Drer\gstt2, Drer\mars, Drer\eef1g" "Scer\CAM1, Scer\YGR201C, Scer\TEF4, Scer\GTT2, Scer\URE2, Scer\GTT1" "Cele\gst-44, Cele\gst-34, Cele\C02D5.4, Cele\gst-35, Cele\gsto-3, Cele\gsto-2" "Xtro\eef1e1, Xtro\gstt1, Xtro\gsto1, Xtro\eef1g" "Mmus\Gstt4, Mmus\Eef1g, Mmus\Mars, Mmus\Gsto1, Mmus\Eef1e1, Mmus\Gstt2, Mmus\Gstt1, Mmus\Vars, Mmus\Gstt3" "Hsap\EEF1E1, Hsap\GSTT2, Hsap\GSTT2B, Hsap\VARS, Hsap\GSTO2, Hsap\MARS, Hsap\EEF1G, Hsap\GSTO1, Hsap\GSTT1" viable FBgn0065083 snmRNA:765 small non-messenger RNA 765 http://flybase.org/reports/FBgn0065083 non_protein_coding_gene - - - "Dm-765, CR33789, snmRNA:765" - CR33789 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004225 l(3)84Fm lethal (3) 84Fm http://flybase.org/reports/FBgn0004225 - gene - - - l(3)84Fm - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035255 RabX5 RabX5 http://flybase.org/reports/FBgn0035255 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 synapse ; GO:0045202 | inferred from direct assay "DmRabX5, CG7980, RabX5, rabX5, Q9W0A7" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7980 11-Aug-17 DroID_v2017_08 "Drer\rab34a, Drer\rab34b, Drer\rpl23a, Drer\rab36" "Scer\TEM1, Scer\RHO4, Scer\RPL25, Scer\YPT6" "Cele\Y71H2AM.12, Cele\C56E6.2" "Xtro\rab34, Xtro\rpl23a, Xtro\rab36" "Mmus\Rpl23a, Mmus\Rab36, Mmus\Rab34" "Hsap\NARR, Hsap\RAB36, Hsap\RAB34, Hsap\RPL23A" "viable,fertile" FBgn0037705 mura murashka http://flybase.org/reports/FBgn0037705 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN001021049 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:18052 long-term memory ; GO:0007616 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:18052 learning or memory ; GO:0007611 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN001021049 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:18052 "CG9381, CG9382, mura, Mura" "IPR001841:Zinc finger, RING-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9381 11-Aug-17 DroID_v2017_08 "Drer\wu:fb39e10, Drer\rnf44, Drer\rnf126, Drer\rnf32, Drer\rnf11a, Drer\zswim2, Drer\si:dkey-51a16.9, Drer\rnf38, Drer\rnf24, Drer\rlim, Drer\rnf165a, Drer\znrf3, Drer\rnf103, Drer\rnf165b, Drer\rnf11b, Drer\rnf130, Drer\rnf6, Drer\rnf215, Drer\si:ch211-81a5.1, Drer\si:ch1073-392o20.1, Drer\rnf150, Drer\rnf115, Drer\pja2, Drer\rnf111, Drer\rnf150a, Drer\zgc:175214" "Scer\ASR1, Scer\YBR062C" "Cele\toe-4, Cele\plr-1" "Xtro\rnf11, Xtro\rlim, Xtro\rnf24, Xtro\rnf181, Xtro\rnf115, Xtro\znrf3, Xtro\rnf149, Xtro\rnf11.2, Xtro\rnf32, Xtro\chmp3, Xtro\rnf44, Xtro\rnf111, Xtro\pja2, Xtro\rnf38, Xtro\rnf126" "Mmus\Rnf24, Mmus\Rnf44, Mmus\Znrf3, Mmus\Rnf43, Mmus\Rnf165, Mmus\Rnf111, Mmus\Rnf126, Mmus\Rnf103, Mmus\Pja2, Mmus\Rnf181, Mmus\Rnf130, Mmus\Rnf150, Mmus\Rnf11, Mmus\4930595M18Rik, Mmus\Rnf38, Mmus\Rnf215, Mmus\Rnf149, Mmus\Pja1, Mmus\Rnf122, Mmus\Rnf115, Mmus\Rlim, Mmus\Rnf32, Mmus\Rnf6, Mmus\Zswim2" "Hsap\ZNRF3, Hsap\RNF43, Hsap\CHMP3, Hsap\RNF6, Hsap\RNF215, Hsap\PJA1, Hsap\RNF130, Hsap\RNF149, Hsap\RNF181, Hsap\RNF150, Hsap\RNF103, Hsap\RNF122, Hsap\RNF11, Hsap\RNF24, Hsap\RNF38, Hsap\PJA2, Hsap\RNF126, Hsap\RNF115, Hsap\RNF44, Hsap\RLIM, Hsap\ZSWIM2, Hsap\RNF111, Hsap\RNF165, Hsap\RNF32" "viable,fertile,learning defective,memory defective,chemical resistant" DRSC23145 K 1.603695716 -0.197794796 FBgn0046880 Obp56b Odorant-binding protein 56b http://flybase.org/reports/FBgn0046880 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "56b, CG15129, OBP56b, CG30129, Obp56b, DmelObp56b" IPR006170:Pheromone/general odorant binding protein CG30129 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029079 icln icln http://flybase.org/reports/FBgn0029079 protein_coding_gene - spliceosomal snRNP assembly ; GO:0000387 | inferred from electronic annotation with InterPro:IPR003521 cell volume homeostasis ; GO:0006884 | inferred from electronic annotation with InterPro:IPR003521 chloride transport ; GO:0006821 | inferred from electronic annotation with InterPro:IPR003521 plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR003521 pICln-Sm protein complex ; GO:0034715 | inferred from electronic annotation with InterPro:IPR003521 cytosol ; GO:0005829 | inferred from electronic annotation with InterPro:IPR003521 methylosome ; GO:0034709 | inferred from electronic annotation with InterPro:IPR003521 "CG4924, icln, pICln" IPR003521:ICln CG4924 11-Aug-17 DroID_v2017_08 Drer\clns1a Scer\LOT5 "Cele\icln-1, Cele\icl-1" Xtro\clns1a Mmus\Clns1a Hsap\CLNS1A viable FBgn0040041 CG17506 - http://flybase.org/reports/FBgn0040041 protein_coding_gene - - - "CG40223, CG17506" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264708 CR43977 - http://flybase.org/reports/FBgn0264708 non_protein_coding_gene - - - CR43977 - CR43977 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016900 l(3)72CDb lethal (3) 72CDb http://flybase.org/reports/FBgn0016900 - gene - - - l(3)72CDb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable" FBgn0038852 HHEX Hematopoietically expressed homeobox http://flybase.org/reports/FBgn0038852 protein_coding_gene "transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001227 | inferred from biological aspect of ancestor with PANTHER:PTN001963821 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with MGI:MGI:96086 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001963821" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:96086 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN001963821 response to sucrose ; GO:0009744 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype glucose metabolic process ; GO:0006006 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:96086 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001963821 "CG7056, HHEX, dHHEX" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR020479:Homeobox domain, metazoa" CG7056 11-Aug-17 DroID_v2017_08 "Drer\hhex, Drer\hmx2, Drer\tlx2, Drer\tlx1, Drer\hmx3b, Drer\hmx4, Drer\LOC100008066, Drer\hmx1" - "Cele\ceh-93, Cele\pha-2, Cele\ceh-51, Cele\ttx-1, Cele\ceh-76, Cele\mls-2" "Xtro\nkx3-1, Xtro\tlx3, Xtro\tlx1, Xtro\tlx2, Xtro\hmx3, Xtro\hmx1, Xtro\hmx2, Xtro\hhex" "Mmus\Tlx2, Mmus\Hmx3, Mmus\Hhex, Mmus\Hmx2, Mmus\Hmx1, Mmus\Nkx2-9, Mmus\Nkx3-1, Mmus\Dbx2, Mmus\Tlx3, Mmus\Tlx1" "Hsap\HHEX, Hsap\HMX3, Hsap\NKX3-1, Hsap\HMX2, Hsap\TLX2, Hsap\TLX1, Hsap\TLX3, Hsap\DBX2, Hsap\ALX3" "lethal,chemical conditional,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,chemical sensitive,male limited,small body,female limited,viable,fertile" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC16186 E 1.06117676 -0.050501548 3.497706995 -1.716624444 -1.272295111 -0.103251705 FBgn0039470 CG6296 - http://flybase.org/reports/FBgn0039470 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG6296, DmelL7" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6296 11-Aug-17 DroID_v2017_08 "Drer\lipca, Drer\lpl, Drer\LOC101884800, Drer\lipib, Drer\LOC100331214, Drer\pla1a, Drer\lipg, Drer\lipia" - - "Xtro\lipg, Xtro\lpl" "Mmus\Lipi, Mmus\Pnliprp1, Mmus\Pnliprp2, Mmus\Lpl, Mmus\Lipg, Mmus\Pla1a, Mmus\Liph, Mmus\Pnlip, Mmus\Lipc" "Hsap\PNLIPRP2, Hsap\PNLIPRP3, Hsap\PLA1A, Hsap\LPL, Hsap\PNLIPRP1, Hsap\PNLIP, Hsap\LIPH, Hsap\LIPC, Hsap\LIPI, Hsap\LIPG" "viable,fertile" FBgn0054024 CR34024 - http://flybase.org/reports/FBgn0054024 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1090, HDC15672, CG34024, CR34024" - CR34024 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002285 soba suppressor of bulge and argos http://flybase.org/reports/FBgn0002285 - gene - - - "l(3)std4, l(3)73Aj, soba" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0044518 ifm(2)RU486 indirect flight muscle (2) RU486 http://flybase.org/reports/FBgn0044518 gene - - - "RU486, ifm(2)RU486" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,sterile,recessive,flight defective" "wing,indirect flight muscle" FBgn0267526 CR45866 - http://flybase.org/reports/FBgn0267526 non_protein_coding_gene - - - CR45866 - CR45866 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028590 l(3)L4222a lethal (3) L4222a http://flybase.org/reports/FBgn0028590 gene - - - "l(3)L4222, l(3)L4222a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266164 CR44870 - http://flybase.org/reports/FBgn0266164 non_protein_coding_gene - - - CR44870 - CR44870 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022103 l(2)k07118b lethal (2) k07118b http://flybase.org/reports/FBgn0022103 - gene - - - "l(2)k07118, l(2)k07118b, l(2)k0711b, (2)k07118b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038492 Mur89F Mucin related 89F http://flybase.org/reports/FBgn0038492 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "CT13556, Mur89F, CG4090" IPR002557:Chitin binding domain CG4090 11-Aug-17 DroID_v2017_08 "Drer\chia.2, Drer\ovgp1, Drer\chia.5, Drer\si:ch211-226m16.2" Scer\CTS2 "Cele\cbd-1, Cele\W03F11.1" "Xtro\chit1, Xtro\chia, Xtro\LOC548945, Xtro\ctbs" "Mmus\Ovgp1, Mmus\Chit1, Mmus\Chil1, Mmus\Chil3, Mmus\Ctbs, Mmus\Chil6, Mmus\Chia1, Mmus\Chil4, Mmus\Chil5" "Hsap\CHIA, Hsap\OVGP1, Hsap\CHI3L1, Hsap\CHI3L2, Hsap\CHIT1" viable DRSC15544 I 1.745683474 0.433702246 -0.635136681 -0.055825722 -0.394560534 -0.977250275 FBgn0267579 CR45919 - http://flybase.org/reports/FBgn0267579 non_protein_coding_gene - - - "CR45919, pri-mir-124" - CR45919 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064153 p124 p124 http://flybase.org/reports/FBgn0064153 gene - - - "P124, p124" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261814 CR42756 - http://flybase.org/reports/FBgn0261814 non_protein_coding_gene - - - CR42756 - CR42756 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003922 snRNA:U2:38ABa small nuclear RNA U2 at 38ABa http://flybase.org/reports/FBgn0003922 FBgn0003919 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay "U2:38ABa, U2, dU2, U2 snRNA, U2-38ABa, snRNA[[1]], K6, Dm U2-141A, D.U2-3, U2-141A, 141A, snRNA-U2-141A, snRNA:U2:39B, snRNA:U2, snRNA2, snRNA1, U2snRNA39B, CR32882, U2snRNA, snRNA:U2:38ABa, U2:39AB, 38A U2" - CR32882 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260346 GSd497 - http://flybase.org/reports/FBgn0260346 gene - - - GSd497 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,intersegmental nerve" FBgn0040759 CG13177 - http://flybase.org/reports/FBgn0040759 protein_coding_gene - - - CG13177 - CG13177 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038359 CG5614 - http://flybase.org/reports/FBgn0038359 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5614 IPR006594:LIS1 homology motif CG5614 11-Aug-17 DroID_v2017_08 Drer\fopnl - - - Mmus\Fopnl Hsap\FOPNL "viable,fertile" FBgn0069240 fz::smo fz::smo http://flybase.org/reports/FBgn0069240 engineered_fusion_gene - - - fz::smo - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,costal cell,wing vein,ectopic,1st posterior cell" FBgn0014355 lup-2 loop unfolding protein-2 http://flybase.org/reports/FBgn0014355 - gene - sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype - "ms(3)HB267, lup-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" "Y chromosome loop,spermatid axoneme,axonemal dynein complex,axonemal microtubule | ectopic,axonemal microtubule | supernumerary" FBgn0038662 Mpc1 Mitochondrial pyruvate carrier http://flybase.org/reports/FBgn0038662 protein_coding_gene pyruvate transmembrane transporter activity ; GO:0050833 | inferred from sequence or structural similarity with SGD:S000003048 pyruvate transmembrane transporter activity ; GO:0050833 | inferred from biological aspect of ancestor with PANTHER:PTN000365848 mitochondrial pyruvate transport ; GO:0006850 | inferred from sequence or structural similarity with SGD:S000003048 mitochondrial pyruvate transmembrane transport ; GO:1902361 | inferred from biological aspect of ancestor with PANTHER:PTN000365848 pyruvate metabolic process ; GO:0006090 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay integral component of mitochondrial inner membrane ; GO:0031305 | inferred from sequence or structural similarity with SGD:S000003048 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000365848 "CG14290, Mpc1, dMPC1" IPR005336:Mitochondrial pyruvate carrier CG14290 11-Aug-17 DroID_v2017_08 Drer\mpc1 Scer\MPC1 Cele\R07E5.13 Xtro\mpc1 Mmus\Mpc1 "Hsap\MPC1, Hsap\MPC1L" "viable,fertile,neuroanatomy defective,lethal,nutrition conditional" neurite | pharate adult stage FBgn0044071 E(rst)K137 E(rst)K137 http://flybase.org/reports/FBgn0044071 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "K137, E(rst)K137" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259453 EP-J63.2 - http://flybase.org/reports/FBgn0259453 gene - - - EP-J63.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0265859 CR44648 - http://flybase.org/reports/FBgn0265859 non_protein_coding_gene - - - CR44648 - CR44648 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034362 CG5323 - http://flybase.org/reports/FBgn0034362 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5323 "IPR008560:Protein of unknown function DUF842, eukaryotic" CG5323 11-Aug-17 DroID_v2017_08 Drer\fam136a - Cele\ZK637.2 Xtro\fam136a Mmus\Fam136a Hsap\FAM136A viable FBgn0069426 JJF015 JJF015 http://flybase.org/reports/FBgn0069426 gene - - - JJF015 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0025763 l(3)89Em lethal (3) 89Em http://flybase.org/reports/FBgn0025763 - gene - - - "l(3)M96, l(3)89Em" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035797 CG14837 - http://flybase.org/reports/FBgn0035797 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14837 - CG14837 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016080 xmas-1 xmas-1 http://flybase.org/reports/FBgn0016080 "FBgn0030822, FBgn0052561" protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG8919, xmas, l(1)15Ea, ms3, ms(1)3, m(1)3, CG32561, xmas-1" - CG32561 11-Aug-17 DroID_v2017_08 "Drer\mcm3ap, Drer\si:zfos-452g4.1" Scer\SAC3 - Xtro\mcm3ap "Mmus\Mcm3ap, Mmus\Sac3d1" "Hsap\MCM3AP, Hsap\SAC3D1" "meiotic cell cycle defective,male sterile,viable" FBgn0082988 snoRNA:Psi28S-2442b snoRNA:Psi28S-2442b http://flybase.org/reports/FBgn0082988 snoRNA_gene - - - "snoRNA:Psi28S-2442b, psi28s-2442b, CR34612, chr3R:1424176..1424319" - CR34612 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003697 thic thickened aristae http://flybase.org/reports/FBgn0003697 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available thic - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,eye color defective" "arista,sex comb,eye" FBgn0032636 CG5043 - http://flybase.org/reports/FBgn0032636 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5043 - CG5043 11-Aug-17 DroID_v2017_08 - - Cele\ceh-44 - - - FBgn0033207 CG12826 - http://flybase.org/reports/FBgn0033207 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12826 - CG12826 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069075 ttf tintenfisch http://flybase.org/reports/FBgn0069075 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available ttf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic thorax,germline clone,maternal effect,embryonic head,embryonic abdominal segment 7,embryonic abdominal segment 8" FBgn0268063 ltl larval translucida http://flybase.org/reports/FBgn0268063 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "ltl, l(3)tr, lincRNA.S4366, CG32372, CG7545, CT15760, F, CG14836, anon-EST:CL1a11" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype" CG32372 11-Aug-17 DroID_v2017_08 "Drer\chadlb, Drer\chadla" - - Xtro\slitrk6 "Mmus\Gp1ba, Mmus\Tlr4" Hsap\TLR4 FBgn0026249 ego early germ cell overproliferation http://flybase.org/reports/FBgn0026249 - gene - - - ego - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035211 CG2211 - http://flybase.org/reports/FBgn0035211 protein_coding_gene - - - "anon-WO0118547.230, CG2211" - CG2211 11-Aug-17 DroID_v2017_08 - - Cele\jmjd-4 - - Hsap\JMJD6 viable FBgn0060369 l(3)S138102 lethal (3) S138102 http://flybase.org/reports/FBgn0060369 gene - - - "1381/02, l(3)S138102" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083981 RunxA Runt related A http://flybase.org/reports/FBgn0083981 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR008967, InterPro:IPR012346, InterPro:IPR013524 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000040 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR012346, InterPro:IPR013524" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR008967, InterPro:IPR012346, InterPro:IPR013524 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR012346" "CG1379, CG15453, CG34145, RunxA" "IPR000040:Acute myeloid leukemia 1 protein (AML1)/Runt, IPR008967:p53-like transcription factor, DNA-binding, IPR012346:p53/RUNT-type transcription factor, DNA-binding domain, IPR013524:Runt domain" CG34145 11-Aug-17 DroID_v2017_08 "Drer\runx2b, Drer\runx1, Drer\runx3, Drer\runx2a" - Cele\rnt-1 "Xtro\runx3, Xtro\runx2, Xtro\runx1" "Mmus\Runx3, Mmus\Runx1, Mmus\Runx2" "Hsap\RUNX1, Hsap\RUNX3, Hsap\RUNX2" "lethal,neuroanatomy defective" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa" FBgn0025141 ms(3)A6 ms(3)A6 http://flybase.org/reports/FBgn0025141 - gene - - - ms(3)A6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0267738 CR46069 - http://flybase.org/reports/FBgn0267738 non_protein_coding_gene - - - "CR46069, Mgn94068" - CR46069 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032175 CG13131 - http://flybase.org/reports/FBgn0032175 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13131 - CG13131 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0259478 EP-336 - http://flybase.org/reports/FBgn0259478 gene - - - EP-336 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin,chaeta,ectopic" FBgn0265197 CG44257 - http://flybase.org/reports/FBgn0265197 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44257 - CG44257 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023085 fcG fcG http://flybase.org/reports/FBgn0023085 - gene - - - fcG - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083000 snoRNA:Psi28S-1192b snoRNA:Psi28S-1192b http://flybase.org/reports/FBgn0083000 snoRNA_gene - - - "snoRNA:Psi28S-1192b, Psi28S-1192b, psi28S-1192b, CR34596, chrX:16978184..16978371" - CR34596 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001589 l(1)carot6 lethal (1) carot6 http://flybase.org/reports/FBgn0001589 - gene - - - l(1)carot6 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265610 CG44428 - http://flybase.org/reports/FBgn0265610 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44428 - CG44428 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032787 CG10195 - http://flybase.org/reports/FBgn0032787 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797" - - CG10195 "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like" CG10195 11-Aug-17 DroID_v2017_08 Drer\nudt19 - Cele\ndx-7 Xtro\nudt19 Mmus\Nudt19 Hsap\NUDT19 "viable,fertile" DRSC02026 I 0.919479269 2.004256654 -0.465537298 0.716693186 -0.803214372 -0.06901763 FBgn0000377 crn crooked neck http://flybase.org/reports/FBgn0000377 "FBgn0004044, FBgn0042162" protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:15762 "axon ensheathment ; GO:0008366 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 oenocyte development ; GO:0007438 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay nuclear speck ; GO:0016607 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG3193, Crn, EG:30B8.1, yok, l30, RC63, l(1)2, l(1)CRN, N10, N5, 62D9.a, crn, CG18842, l(1)crn, l(1)N7, l(1)2Fa" "IPR003107:HAT (Half-A-TPR) repeat, IPR013026:Tetratricopeptide repeat-containing domain, IPR011990:Tetratricopeptide-like helical domain" CG3193 11-Aug-17 DroID_v2017_08 Drer\crnkl1 Scer\CLF1 Cele\M03F8.3 Xtro\crnkl1 Mmus\Crnkl1 Hsap\CRNKL1 " embryonic stage , adult stage | female "

ubiquitous "some die during embryonic stage,recessive,lethal - all die before end of embryonic stage,wild-type,lethal,germline clone,dominant,neuroanatomy defective,cell lethal,viable,lethal - all die before end of pupal stage,some die during pupal stage" "glial cell,embryo,Malpighian tubule,embryonic Malpighian tubule,embryonic/larval neuroblast,ganglion mother cell,embryonic/larval glial cell,peripheral glial cell,embryonic/larval oenocyte precursor" DRSC18184 EK -0.735668429 0.757430033 2.329051917 0.656615062 -1.877734444 0.163732937 FBgn0026713 l(1)G0007 lethal (1) G0007 http://flybase.org/reports/FBgn0026713 "FBgn0026709, FBgn0027309, FBgn0028281, FBgn0029047, FBgn0030546, FBgn0030550, FBgn0040139, FBgn0040178, FBgn0040194, FBgn0044447, FBgn0044450, FBgn0052604" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000001794 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338" "inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000001794" spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000001794 spliceosomal complex ; GO:0005681 | inferred from biological aspect of ancestor with PANTHER:PTN000433947 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "l(1)G0476, CG1405, CG32604, cg1405, l(1)G0103, l(1)G0176, l(1)G0491, l(1)G0308, l(1)G0028, l(1)G0416, EP784, EP764, CG1375, l(1)G0007, lethal (1) G0007, Prp16, prp16" "IPR001650:Helicase, C-terminal, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011545:DEAD/DEAH box helicase domain" CG32604 11-Aug-17 DroID_v2017_08 "Drer\dhx32a, Drer\dhx38, Drer\zgc:158828, Drer\dhx15, Drer\dhx8, Drer\dhx16, Drer\dhx33, Drer\dhx32b" "Scer\PRP16, Scer\DHR2, Scer\PRP43, Scer\PRP2, Scer\PRP22" "Cele\ddx-35, Cele\let-355, Cele\ddx-15, Cele\mog-5, Cele\mog-1, Cele\mog-4" "Xtro\dhx16, Xtro\dhx15, Xtro\dhx35, Xtro\dhx33, Xtro\dhx38, Xtro\dhx8" "Mmus\Dhx8, Mmus\Dhx16, Mmus\Dhx33, Mmus\Dhx35, Mmus\Dhx38, Mmus\Dhx32, Mmus\Dqx1, Mmus\Dhx15" "Hsap\DHX8, Hsap\DHX32, Hsap\DHX16, Hsap\DHX38, Hsap\DHX33, Hsap\DQX1, Hsap\DHX35, Hsap\DHX15" "behavior defective,recessive,long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,male limited,viable,fertile,lethal,neuroanatomy defective,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,some die during pupal stage" "macrochaeta,intersegmental nerve,anterior fascicle & synapse,embryonic/larval brain,mesothoracic tergum,trichogen cell" FBgn0005154 l(2)G97 lethal (2) G97 http://flybase.org/reports/FBgn0005154 - gene - - - l(2)G97 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0084016 CG41453 - http://flybase.org/reports/FBgn0084016 protein_coding_gene - - - CG41453 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030946 CG6659 - http://flybase.org/reports/FBgn0030946 protein_coding_gene mannosyltransferase activity ; GO:0000030 | inferred from biological aspect of ancestor with PANTHER:PTN001266774 protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan ; GO:0018406 | inferred from biological aspect of ancestor with PANTHER:PTN001266774 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR018732 nuclear inner membrane ; GO:0005637 | inferred from biological aspect of ancestor with PANTHER:PTN001266774 CG6659 "IPR018732:Dpy-19/Dpy-19-like, IPR030038:C-mannosyltransferase Dpy-19" CG6659 11-Aug-17 DroID_v2017_08 "Drer\dpy19l1l, Drer\dpy19l3" - Cele\dpy-19 "Xtro\dpy19l4, Xtro\dpy19l1" "Mmus\Dpy19l3, Mmus\Dpy19l2, Mmus\Dpy19l4, Mmus\Dpy19l1" "Hsap\DPY19L3, Hsap\DPY19L2, Hsap\DPY19L4, Hsap\DPY19L1" "viable,fertile" FBgn0033132 Tsp42Ej Tetraspanin 42Ej http://flybase.org/reports/FBgn0033132 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cellular response to high light intensity ; GO:0071486 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model lysosome ; GO:0005764 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "sun, CG12143, Sun, Dm.Tsp42Ej, Tsp42Ej, tsp42ej" "IPR018499:Tetraspanin/Peripherin, IPR008952:Tetraspanin, EC2 domain" CG12143 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-139j3.4, Drer\tspan37" - Cele\tsp-13 Xtro\LOC100145428 - "Hsap\TSPAN19, Hsap\TSPAN16, Hsap\TSPAN6" "viable,fertile,visible" "retina,trichogen cell" FBgn0264524 ff18 - http://flybase.org/reports/FBgn0264524 gene - - - ff18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" spermatid FBgn0065655 l(2)SH0723 lethal (2) SH0723 http://flybase.org/reports/FBgn0065655 gene - - - l(2)SH0723 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016123 Alp4 Alkaline phosphatase 4 http://flybase.org/reports/FBgn0016123 FBgn0010913 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 epithelial fluid transport ; GO:0042045 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern nervous system development ; GO:0007399 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 extracellular space ; GO:0005615 | inferred from sequence model "CG1462, pMY51, l(3)07028, aph-4, Aph-4, Alp4" "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG1462 11-Aug-17 DroID_v2017_08 "Drer\alpi.1, Drer\alpl, Drer\alpi.2, Drer\alp3" Scer\PHO8 - "Xtro\alpi.1, Xtro\alpl" "Mmus\Alpi, Mmus\Alppl2, Mmus\Alpl, Mmus\Akp3" "Hsap\ALPL, Hsap\ALPPL2, Hsap\ALPI, Hsap\ALPP" " adult stage , larval stage && adult stage " " Malpighian tubule

, ellipsoid body

" "viable,partially lethal - majority die,recessive,lethal" adult Malpighian tubule FBgn0267017 CR45461 - http://flybase.org/reports/FBgn0267017 non_protein_coding_gene - - - CR45461 - CR45461 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040109 l(3)tk21 lethal (3) tk21 http://flybase.org/reports/FBgn0040109 gene - - - "tk21, l(3)tk21" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060897 l(3)S044306 lethal (3) S044306 http://flybase.org/reports/FBgn0060897 gene - - - "0443/06, l(3)S044306" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0261918 EndoA::Hsap\ARFIP2 - http://flybase.org/reports/FBgn0261918 engineered_fusion_gene - - - "endoA::Hsap\ARFIP2, EndoA::Hsap\ARFIP2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004483 l(1)air10 lethal aberrant immune response 10 http://flybase.org/reports/FBgn0004483 - gene - - - "air10, l(1)air10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass" FBgn0052856 CG32856 - http://flybase.org/reports/FBgn0052856 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR029138 molecular_function ; GO:0003674 | no biological data available" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from electronic annotation with InterPro:IPR029138 transcription initiation from RNA polymerase III promoter ; GO:0006384 | inferred from electronic annotation with InterPro:IPR029138 biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR029138 cellular_component ; GO:0005575 | no biological data available "BcDNA:GM32296, CG32856" IPR029138:snRNA-activating protein complex subunit 5 CG32856 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040038 klhl10 kelch like family member 10 http://flybase.org/reports/FBgn0040038 protein_coding_gene - sperm individualization ; GO:0007291 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from mutant phenotype Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from physical interaction with Cul3 "anon-WO0140519.152, CG12423, klhl10" "IPR000210:BTB/POZ domain, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR015916:Galactose oxidase, beta-propeller, IPR015915:Kelch-type beta propeller" CG12423 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-253p14.2, Drer\LOC101882758, Drer\klhdc8a, Drer\kbtbd11, Drer\klhdc8b, Drer\klhl10b.1, Drer\klhl10a, Drer\klhl32, Drer\klhl11, Drer\klhl42, Drer\klhl10b.2" - "Cele\C53A5.9, Cele\kel-10, Cele\C53A5.11, Cele\C53A5.6, Cele\spe-26, Cele\F47D12.7" "Xtro\klhl10, Xtro\kbtbd13, Xtro\klhdc8a, Xtro\klhdc8b, Xtro\kbtbd11, Xtro\klhl32" "Mmus\Klhl33, Mmus\Klhl11, Mmus\Klhl42, Mmus\Klhdc8b, Mmus\Klhl32, Mmus\Klhl10, Mmus\Kbtbd13, Mmus\Klhdc8a, Mmus\Klhdc7a, Mmus\Klhdc7b, Mmus\Kbtbd11" "Hsap\KLHL32, Hsap\KLHDC7B, Hsap\KLHL42, Hsap\KLHDC8B, Hsap\KBTBD11, Hsap\KLHL33, Hsap\KBTBD13, Hsap\KLHL10, Hsap\KLHDC7A, Hsap\KLHDC8A, Hsap\KLHL11" "viable,visible,male sterile,recessive" "eye,ommatidium,spermatid" DRSC20925 I 1.728214047 0.063898099 -0.681175424 0.391517731 FBgn0011194 l(1)302-3 lethal (1) 302-3 http://flybase.org/reports/FBgn0011194 FBgn0010202 gene - - - "302-3, l(1)302-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263886 l(3)C26 - http://flybase.org/reports/FBgn0263886 gene - - - l(3)C26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0051301 CG31301 - http://flybase.org/reports/FBgn0051301 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467, InterPro:IPR001374" signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001043816 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN001043816 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001043816 "CG31301, CG12258" "IPR000467:G-patch domain, IPR001374:R3H domain, IPR034071:NF-kappaB-repression factor, R3H domain, IPR021859:XRN-Two Binding Domain, XTBD" CG31301 11-Aug-17 DroID_v2017_08 "Drer\cdkn2aipnl, Drer\nkrf, Drer\cdkn2aip" - Cele\paxt-1 "Xtro\cdkn2aip, Xtro\cdkn2aipnl, Xtro\nkrf" "Mmus\Cdkn2aipnl, Mmus\Nkrf, Mmus\Cdkn2aip" "Hsap\CDKN2AIP, Hsap\NKRF, Hsap\CDKN2AIPNL" "viable,fertile" FBgn0067402 Rst(2)DDT-EMS2 Resistant to DDT on II EMS2 http://flybase.org/reports/FBgn0067402 gene - - - "Rst(2)DDT, Rst(2)DDT-EMS2" - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0037894 Ranbp9 Ranbp9 http://flybase.org/reports/FBgn0037894 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001494 - "CG5252, Ranbp9" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG5252 11-Aug-17 DroID_v2017_08 Drer\ipo9 Scer\KAP114 Cele\xpo-2 Xtro\ipo9 Mmus\Ipo9 Hsap\IPO9 viable FBgn0266259 CG44954 - http://flybase.org/reports/FBgn0266259 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44954, lincRNA.900" - CG44954 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033806 FLASH FLICE-associated huge protein http://flybase.org/reports/FBgn0033806 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Lsm11 mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype histone locus body ; GO:0035363 | inferred from direct assay histone pre-mRNA 3'end processing complex ; GO:0071204 | inferred from direct assay "dFLASH, FLASH, CG4616" - CG4616 11-Aug-17 DroID_v2017_08 Drer\casp8ap2 - - - Mmus\Casp8ap2 Hsap\CASP8AP2 "viable,female sterile,female semi-sterile" FBgn0036109 Cpr67Fa2 Cuticular protein 67Fa2 http://flybase.org/reports/FBgn0036109 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:LP01241, CG18349, Cpr67Fa2, DmelCpr67Fa2" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG18349 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - FBgn0040753 CG13341 - http://flybase.org/reports/FBgn0040753 protein_coding_gene - - - CG13341 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004993 Cli Clipped wings http://flybase.org/reports/FBgn0004993 - gene - - - Cli - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,dominant" wing FBgn0060543 l(3)S099102 lethal (3) S099102 http://flybase.org/reports/FBgn0060543 gene - - - "0991/02, l(3)S099102" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266186 Vamp7 Vesicle-associated membrane protein 7 http://flybase.org/reports/FBgn0266186 protein_coding_gene "SNARE binding ; GO:0000149 | inferred from physical interaction with Snap29, Syx17 syntaxin binding ; GO:0019905 | inferred from sequence or structural similarity with RGD:619747 SNAP receptor activity ; GO:0005484 | inferred from physical interaction with Snap29, Syx17 SNAP receptor activity ; GO:0005484 | inferred by curator from GO:0006906,GO:0019905,GO:0031201" endocytosis ; GO:0006897 | inferred from biological aspect of ancestor with PANTHER:PTN000474284 vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 vesicle fusion ; GO:0006906 | inferred from sequence or structural similarity with RGD:619747 endosome to lysosome transport ; GO:0008333 | inferred from sequence or structural similarity with RGD:619747 autophagosome maturation ; GO:0097352 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001388 SNARE complex ; GO:0031201 | inferred from direct assay autolysosome ; GO:0044754 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from sequence or structural similarity with RGD:619747 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with RGD:619747 "VAMP7, CG1599, TI-VAMP, Vamp7, dVamp7" "IPR001388:Synaptobrevin, IPR010908:Longin domain, IPR011012:Longin-like domain" CG1599 11-Aug-17 DroID_v2017_08 "Drer\sybl1, Drer\vamp1, Drer\sec22bb, Drer\sec22a, Drer\zgc:92912, Drer\sec22ba, Drer\vamp8, Drer\vamp2, Drer\sec22c" Scer\NYV1 "Cele\snb-1, Cele\vamp-7, Cele\vamp-8, Cele\sec-22" "Xtro\sec22b, Xtro\vamp7, Xtro\vamp2, Xtro\sec22c, Xtro\vamp3, Xtro\vamp1, Xtro\sec22a, Xtro\ykt6, Xtro\vamp4" "Mmus\Sec22a, Mmus\Vamp1, Mmus\Ykt6, Mmus\Vamp3, Mmus\Vamp7, Mmus\Sec22c, Mmus\Vamp2, Mmus\Vamp4, Mmus\Vamp8, Mmus\Sec22b, Mmus\Gm35911" "Hsap\SEC22C, Hsap\VAMP2, Hsap\SEC22B, Hsap\VAMP8, Hsap\YKT6, Hsap\VAMP7, Hsap\VAMP1, Hsap\VAMP3, Hsap\VAMP4" FBgn0047114 CG31142 - http://flybase.org/reports/FBgn0047114 protein_coding_gene - - - "BcDNA:RE39515, CG31142" "IPR019191:Essential protein Yae1, N-terminal" CG31142 11-Aug-17 DroID_v2017_08 Drer\otulina - - Xtro\yae1d1 Mmus\Yae1d1 Hsap\YAE1D1 "viable,visible" trichogen cell FBgn0023218 E(lz)205 E(lz)205 http://flybase.org/reports/FBgn0023218 - gene - - - E(lz)205 - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0267152 CR45592 - http://flybase.org/reports/FBgn0267152 non_protein_coding_gene - - - CR45592 - CR45592 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011694 EbpII Ejaculatory bulb protein II http://flybase.org/reports/FBgn0011694 - protein_coding_gene - "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern post-mating behavior ; GO:0045297 | inferred from sequence or structural similarity with UniProtKB:Q9U6L5 negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "PEB, PEBmeII, CG2665, PebII, PEBII, PEB2, EbpII" - CG2665 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069070 194-26 194-26 http://flybase.org/reports/FBgn0069070 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 194-26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" FBgn0266395 CR45035 - http://flybase.org/reports/FBgn0266395 non_protein_coding_gene - - - CR45035 - CR45035 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000072 Ama-1 alpha Amanitin-resistant 1 http://flybase.org/reports/FBgn0000072 - gene - - - Ama-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022241 l(2)k02206 lethal (2) k02206 http://flybase.org/reports/FBgn0022241 - gene - - - "l(2)k02206, l(2)K02206" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266316 CR44981 - http://flybase.org/reports/FBgn0266316 non_protein_coding_gene - - - CR44981 - CR44981 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064245 E(tc) Enhancer of terminal gene conversion http://flybase.org/reports/FBgn0064245 gene molecular_function ; GO:0003674 | no biological data available telomere maintenance ; GO:0000723 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available E(tc) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260263 GSd491 - http://flybase.org/reports/FBgn0260263 gene - - - GSd491 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261290 CheA84a Chemosensory protein A 84a http://flybase.org/reports/FBgn0261290 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheA29a extracellular region ; GO:0005576 | inferred from sequence model "CG33779, CheA84a" IPR010512:Protein of unknown function DUF1091 CG33779 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264488 CG43896 - http://flybase.org/reports/FBgn0264488 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG43896, CG17824, CG6947" IPR002557:Chitin binding domain CG43896 11-Aug-17 DroID_v2017_08 - - "Cele\Y55F3BR.2, Cele\W03F11.1, Cele\cbd-1" - - - FBgn0052079 CG32079 - http://flybase.org/reports/FBgn0052079 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 "CG11806, CG32079" "IPR013057:Amino acid transporter, transmembrane domain" CG32079 11-Aug-17 DroID_v2017_08 "Drer\slc36a1, Drer\slc36a4" "Scer\AVT3, Scer\AVT4" "Cele\skat-1, Cele\Y43F4B.7, Cele\slc-36.4, Cele\slc-36.5, Cele\slc-36.3, Cele\slc-36.2" "Xtro\slc36a4, Xtro\slc36a1" "Mmus\Slc36a3, Mmus\Slc36a2, Mmus\Slc36a1, Mmus\Slc36a4" "Hsap\SLC36A3, Hsap\SLC36A2, Hsap\SLC36A1, Hsap\SLC36A4" viable FBgn0065245 l(2)SH2139 lethal (2) SH2139 http://flybase.org/reports/FBgn0065245 gene - - - l(2)SH2139 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083978 CG17672 - http://flybase.org/reports/FBgn0083978 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG11271, BcDNA:RH29995, CG17672" IPR029034:Cystine-knot cytokine CG17672 11-Aug-17 DroID_v2017_08 - - - - - - DRSC09230 IEK -1.596333134 -4.667639633 -3.107365662 -7.463030115 -2.166717698 -0.27010061 FBgn0261796 Ote::Hsap\EMD - http://flybase.org/reports/FBgn0261796 engineered_fusion_gene - - - Ote::Hsap\EMD - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039376 CG14354 - http://flybase.org/reports/FBgn0039376 protein_coding_gene molecular_function ; GO:0003674 | no biological data available developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 cellular_component ; GO:0005575 | no biological data available CG14354 IPR007999:Protein of unknown function DUF745 CG14354 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265681 CR44488 - http://flybase.org/reports/FBgn0265681 non_protein_coding_gene - - - CR44488 - CR44488 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052574 Twdlalpha Tweedlealpha http://flybase.org/reports/FBgn0052574 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD neurogenesis ; GO:0022008 | inferred from mutant phenotype body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "CG4724, Twdlalpha, CG32574" IPR004145:Domain of unknown function DUF243 CG32574 11-Aug-17 DroID_v2017_08 "Drer\ppp2r5a, Drer\ppp2r5b, Drer\ppp2r5ca, Drer\ppp2r5ea, Drer\ppp2r5eb, Drer\ppp2r5d" Scer\RTS1 - "Xtro\ppp2r5a, Xtro\ppp2r5e, Xtro\ppp2r5b, Xtro\ppp2r5c" "Mmus\Ppp2r5c, Mmus\Ppp2r5b, Mmus\Ppp2r5d, Mmus\Ppp2r5e, Mmus\Ppp2r5a" "Hsap\PPP2R5A, Hsap\PPP2R5C, Hsap\PPP2R5B, Hsap\PPP2R5D, Hsap\PPP2R5E" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0267122 CR45562 - http://flybase.org/reports/FBgn0267122 non_protein_coding_gene - - - CR45562 - CR45562 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086206 E(ls)1 - http://flybase.org/reports/FBgn0086206 gene - - - E(ls)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033987 ckn caskin http://flybase.org/reports/FBgn0033987 protein_coding_gene "signaling adaptor activity ; GO:0035591 | inferred from physical interaction with Lar, dock protein phosphatase binding ; GO:0019903 | inferred from physical interaction with Lar" axon guidance ; GO:0007411 | inferred from mutant phenotype transmembrane receptor protein tyrosine phosphatase signaling pathway ; GO:0007185 | inferred from genetic interaction with Lar axonogenesis ; GO:0007409 | inferred from mutant phenotype focal adhesion ; GO:0005925 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "BcDNA:GM06913, ckn, CG12424" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG12424 11-Aug-17 DroID_v2017_08 "Drer\ostf1, Drer\si:dkeyp-9d4.3, Drer\LOC564253, Drer\LOC100535210, Drer\caskin1" - "Cele\C46H3.2, Cele\Y106G6H.14" "Xtro\caskin1, Xtro\caskin2" "Mmus\Ostf1, Mmus\Caskin2, Mmus\Caskin1" "Hsap\CASKIN1, Hsap\CASKIN2, Hsap\OSTF1" "learning defective,lethal,neuroanatomy defective,viable" "axon | embryonic stageelav.PLu,fascicle | embryonic stage,intersegmental nerve branch ISNb of A1-7 | embryonic stage,axon | embryonic stageexex-Gal4,intersegmental nerve,intersegmental nerve branch ISNb of A1-7" FBgn0044811 TotF Turandot F http://flybase.org/reports/FBgn0044811 protein_coding_gene - response to bacterium ; GO:0009617 | inferred from expression pattern cellular response to heat ; GO:0034605 | inferred from expression pattern response to UV ; GO:0009411 | inferred from direct assay cellular response to UV ; GO:0034644 | inferred from expression pattern response to heat ; GO:0009408 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with TotA "tot, CG13963, CG31691, TotF, Tot F" IPR010825:Stress-inducible humoral factor Turandot CG31691 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069201 l(2)DJ684 lethal (2) DJ684 http://flybase.org/reports/FBgn0069201 gene - - - l(2)DJ684 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037249 eIF3a eukaryotic translation initiation factor 3 subunit a http://flybase.org/reports/FBgn0037249 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000360893 mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000360893 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with UniProtKB:Q7K550 translation reinitiation ; GO:0002188 | inferred from biological aspect of ancestor with PANTHER:PTN000360893 formation of cytoplasmic translation initiation complex ; GO:0001732 | inferred from biological aspect of ancestor with PANTHER:PTN000360893 translational initiation ; GO:0006413 | inferred from sequence or structural similarity regulation of translational initiation ; GO:0006446 | inferred from sequence or structural similarity with UniProtKB:Q7K550 "multi-eIF complex ; GO:0043614 | inferred from biological aspect of ancestor with PANTHER:PTN000360893 cytosol ; GO:0005829 | inferred from sequence or structural similarity eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay eukaryotic translation initiation factor 3 complex, eIF3e ; GO:0071540 | inferred from biological aspect of ancestor with PANTHER:PTN000360893 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with UniProtKB:Q7K550 eukaryotic translation initiation factor 3 complex, eIF3m ; GO:0071541 | inferred from biological aspect of ancestor with PANTHER:PTN000360893" "CG9805, eIF3-S10, MMAP140, anon-WO0118547.261, eIF3-s10, EIF3-S10, eIF3a" "IPR000717:Proteasome component (PCI) domain, IPR027512:Eukaryotic translation initiation factor 3 subunit A, IPR011991:Winged helix-turn-helix DNA-binding domain" CG9805 11-Aug-17 DroID_v2017_08 Drer\eif3s10 Scer\RPG1 Cele\egl-45 Xtro\eif3a Mmus\Eif3a Hsap\EIF3A "lethal,female fertile,female sterile" DRSC28481 IEK -2.942826222 -1.26835195 -2.418198991 -4.103788702 0.591454306 1.608240127 FBgn0024983 CG4293 - http://flybase.org/reports/FBgn0024983 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000004532 ER to Golgi transport vesicle ; GO:0030134 | inferred from sequence or structural similarity with SGD:S000004532 "154711_at, EG:65F1.1, CG4293" "IPR012936:Endoplasmic reticulum vesicle transporter, C-terminal" CG4293 11-Aug-17 DroID_v2017_08 "Drer\ergic1, Drer\ergic2, Drer\si:ch211-225b10.3, Drer\ergic3" "Scer\ERV46, Scer\ERV41" Cele\C18B12.6 "Xtro\ergic3, Xtro\ergic1, Xtro\ergic2" "Mmus\Ergic1, Mmus\Ergic3, Mmus\Ergic2" "Hsap\ERGIC1, Hsap\ERGIC3, Hsap\ERGIC2" "viable,fertile" FBgn0063649 CG6006 - http://flybase.org/reports/FBgn0063649 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 "BcDNA:SD04753, CG6006" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG6006 11-Aug-17 DroID_v2017_08 - "Scer\PHO84, Scer\HXT9, Scer\GIT1, Scer\HXT2, Scer\HXT5" "Cele\oct-2, Cele\K05F1.6, Cele\str-176, Cele\oat-1, Cele\F17C11.12, Cele\F32H5.4" "Xtro\slc22a15.2, Xtro\slc22a15.1" "Mmus\Slc22a29, Mmus\Slc22a15, Mmus\Slc22a28, Mmus\Slc22a22, Mmus\Slc22a21, Mmus\Slc22a30, Mmus\Slc22a14" "Hsap\SLC22A14, Hsap\SLC22A15, Hsap\SLC22A5" "viable,fertile" FBgn0061077 l(3)S015012 lethal (3) S015012 http://flybase.org/reports/FBgn0061077 gene - - - "0150/12, l(3)S015012" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0023445 dsx-c98D doublesex cognate 98D http://flybase.org/reports/FBgn0023445 - gene - - - "dsx-c98, dsx-c98D" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005457 l(1)v454 lethal (1) v454 http://flybase.org/reports/FBgn0005457 - gene - - - "l(1)454, l(1)v454" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262204 mir-2279 mir-2279 stem loop http://flybase.org/reports/FBgn0262204 miRNA_gene - - - "mir-2279, CR42911, miR-2279, dme-mir-2279" - CR42911 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260252 GSd332 - http://flybase.org/reports/FBgn0260252 gene - - - GSd332 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069067 30-1 30-1 http://flybase.org/reports/FBgn0069067 gene - - - 30-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038337 CG6125 - http://flybase.org/reports/FBgn0038337 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 CG6125 "IPR011547:SLC26A/SulP transporter domain, IPR001902:SLC26A/SulP transporter, IPR002645:STAS domain" CG6125 11-Aug-17 DroID_v2017_08 "Drer\slc26a10, Drer\slc26a4, Drer\slc26a3.2, Drer\slc26a6, Drer\slc26a5, Drer\slc26a1, Drer\si:ch211-117c9.2, Drer\slc26a6l, Drer\slc26a2, Drer\slc26a3.1, Drer\slc26a11" "Scer\YPR003C, Scer\SUL1, Scer\YGR125W, Scer\SUL2" "Cele\sulp-6, Cele\sulp-4, Cele\sulp-1, Cele\sulp-2, Cele\sulp-3, Cele\sulp-8, Cele\sulp-5, Cele\sulp-7" "Xtro\slc26a4, Xtro\slc26a10, Xtro\slc26a6, Xtro\slc26a1, Xtro\slc26a11, Xtro\slc26a5, Xtro\slc26a7, Xtro\slc26a9, Xtro\slc26a2" "Mmus\Slc26a7, Mmus\Slc26a1, Mmus\Slc26a6, Mmus\Slc26a3, Mmus\Slc26a2, Mmus\Slc26a4, Mmus\Slc26a9, Mmus\Slc26a11, Mmus\Slc26a10, Mmus\Slc26a8, Mmus\Slc26a5" "Hsap\SLC26A1, Hsap\SLC26A6, Hsap\SLC26A2, Hsap\SLC26A4, Hsap\SLC26A5, Hsap\SLC26A9, Hsap\SLC26A10, Hsap\SLC26A3, Hsap\SLC26A11, Hsap\SLC26A8, Hsap\SLC26A7" viable FBgn0036106 CG6409 - http://flybase.org/reports/FBgn0036106 protein_coding_gene - - - CG6409 - CG6409 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002018 l(2)37Ab lethal (2) 37Ab http://flybase.org/reports/FBgn0002018 - gene - - - "Ab, l(2)E129, l(2)37Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065779 l(2)SH0446 lethal (2) SH0446 http://flybase.org/reports/FBgn0065779 gene - - - "l(2)SH0446, l(2)SH2 0446" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259289 C174 - http://flybase.org/reports/FBgn0259289 gene - - - C174 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing vein" FBgn0260753 Pdfr Pigment-dispersing factor receptor http://flybase.org/reports/FBgn0260753 protein_coding_gene calcitonin receptor activity ; GO:0004948 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O96690 neuropeptide receptor activity ; GO:0008188 | inferred from physical interaction with UniProtKB:O96690 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model circadian sleep/wake cycle ; GO:0042745 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay gravitaxis ; GO:0042332 | inferred from direct assay circadian temperature homeostasis ; GO:0060086 | inferred from mutant phenotype copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype regulation of circadian sleep/wake cycle ; GO:0042749 | inferred from mutant phenotype circadian behavior ; GO:0048512 | inferred from mutant phenotype positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010579 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity locomotor rhythm ; GO:0045475 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype circadian behavior ; GO:0048512 | inferred from direct assay circadian rhythm ; GO:0007623 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay neuron projection ; GO:0043005 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "han, Pdfr, pdfr, PdfR, PDFR, Han, EG:BACR25B3.3, BACR25B3.3, anon-WO0170980.158, anon-WO0170980.157, CG13758, PDF-R1, Pdf-R1, gop, DmeCG13758, pdfR" "IPR017981:GPCR, family 2-like, IPR017983:GPCR, family 2, secretin-like, conserved site, IPR000832:GPCR, family 2, secretin-like, IPR001879:GPCR, family 2, extracellular hormone receptor domain" CG13758 11-Aug-17 DroID_v2017_08 "Drer\crhr2, Drer\calcrl2, Drer\ghrhrb, Drer\ghrhrl, Drer\pth2r, Drer\adcyap1r1a, Drer\pth1ra, Drer\pth1rb, Drer\ghrhr2, Drer\gipr, Drer\calcr, Drer\gcgra, Drer\vipr1b, Drer\vipr1a, Drer\si:dkeyp-4h4.1, Drer\adcyap1r1b, Drer\vipr2, Drer\ghrhra, Drer\crhr1, Drer\calcrlb, Drer\calcrla, Drer\gcgrb" - "Cele\seb-3, Cele\pdfr-1" "Xtro\calcrl, Xtro\gipr, Xtro\pth1r, Xtro\crhr1.1, Xtro\vipr1, Xtro\crhr1.2, Xtro\pth2r, Xtro\adcyap1r1, Xtro\gcgr" "Mmus\Calcrl, Mmus\Sctr, Mmus\Gipr, Mmus\Pth2r, Mmus\Crhr1, Mmus\Glp2r, Mmus\Crhr2, Mmus\Gcgr, Mmus\Glp1r, Mmus\Vipr2, Mmus\Adcyap1r1, Mmus\Pth1r, Mmus\Ghrhr, Mmus\Calcr, Mmus\Vipr1" "Hsap\GLP2R, Hsap\GIPR, Hsap\SCTR, Hsap\GHRHR, Hsap\CALCR, Hsap\VIPR2, Hsap\CALCRL, Hsap\GCGR, Hsap\GLP1R, Hsap\CRHR2, Hsap\VIPR1, Hsap\CRHR1-IT1-CRHR1, Hsap\PTH2R, Hsap\PTH1R, Hsap\CRHR1, Hsap\ADCYAP1R1" FBgn0260401 MED9 Mediator complex subunit 9 http://flybase.org/reports/FBgn0260401 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with UniProtKB:Q9VEC1 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR011425 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with UniProtKB:Q9VEC1 mediator complex ; GO:0016592 | inferred from sequence or structural similarity with UniProtKB:Q9VEC1 mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000464837 "MED9, CG5134, CG30112, CG30113, BcDNA:LD07740, BcDNA:RH42446, CG42517, med9, Med9" IPR011425:Mediator of RNA polymerase II transcription subunit 9 CG42517 11-Aug-17 DroID_v2017_08 Drer\si:ch73-105m5.1 - - Xtro\med9 Mmus\Med9 Hsap\MED9 DRSC06917 K -1.291763872 1.456262888 -1.139790733 0.540936479 1.892200088 2.329893108 FBgn0035907 GstO1 Glutathione S transferase O1 http://flybase.org/reports/FBgn0035907 protein_coding_gene "glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione dehydrogenase (ascorbate) activity ; GO:0045174 | inferred from direct assay pyrimidodiazepine synthase activity ; GO:0004734 | NOT inferred from direct assay transferase activity, transferring sulfur-containing groups ; GO:0016782 | inferred from direct assay" glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GstO1, GSTO1, CG6662, DmGSTO1" "IPR004045:Glutathione S-transferase, N-terminal, IPR005442:Glutathione S-transferase, omega-class, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG6662 11-Aug-17 DroID_v2017_08 "Drer\gsto2, Drer\gsto1" - "Cele\gsto-3, Cele\gsto-1, Cele\C02D5.4, Cele\gst-44, Cele\gsto-2" "Xtro\LOC100498493, Xtro\gsto2, Xtro\gsto1" "Mmus\Gsto2, Mmus\Gsto1" "Hsap\GSTO1, Hsap\GSTO2" viable DRSC10688 I 0.784712297 1.521778987 -0.353827186 0.135821259 0.443717298 0.145578918 FBgn0011679 NssBF Nuclear single stranded DNA-binding factor http://flybase.org/reports/FBgn0011679 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay - - NssBF - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262972 CR43283 - http://flybase.org/reports/FBgn0262972 non_protein_coding_gene - - - "CR43283, Dm_3R:37919, lincRNA.752" - CR43283 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030239 CG17333 - http://flybase.org/reports/FBgn0030239 protein_coding_gene 6-phosphogluconolactonase activity ; GO:0017057 | inferred from biological aspect of ancestor with PANTHER:PTN000114544 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR005900, InterPro:IPR006148 pentose-phosphate shunt, oxidative branch ; GO:0009051 | inferred from biological aspect of ancestor with PANTHER:PTN000114544" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000114544 "CG17333, Pgls" "IPR005900:6-phosphogluconolactonase, DevB-type, IPR006148:Glucosamine/galactosamine-6-phosphate isomerase" CG17333 11-Aug-17 DroID_v2017_08 "Drer\pgls, Drer\h6pd, Drer\gnpda1" "Scer\SOL3, Scer\SOL1, Scer\SOL4, Scer\SOL2" Cele\Y57G11C.3 "Xtro\h6pd, Xtro\pgls" "Mmus\Pgls, Mmus\H6pd" "Hsap\PGLS, Hsap\H6PD" "viable,fertile" FBgn0051210 CG31210 - http://flybase.org/reports/FBgn0051210 protein_coding_gene - - - "CG31210, CG4836" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040740 CG14494 - http://flybase.org/reports/FBgn0040740 protein_coding_gene - - - CG14494 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069203 l(2)46Fa lethal (2) 46Fa http://flybase.org/reports/FBgn0069203 gene - - - l(2)46Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0028392 anon-50ABb anon-50ABb http://flybase.org/reports/FBgn0028392 gene - - - "B, anon-50ABb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065943 l(2)SH0109 lethal (2) SH0109 http://flybase.org/reports/FBgn0065943 gene - - - "l(2)SH0109, l(2)SH2 0109" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035546 CG11345 - http://flybase.org/reports/FBgn0035546 protein_coding_gene - - - CG11345 - CG11345 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261841 pre-mod(mdg4)-AD - http://flybase.org/reports/FBgn0261841 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-AD, CG42773, RAD" "IPR007588:Zinc finger, FLYWCH-type" CG42773 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033497 CG12912 - http://flybase.org/reports/FBgn0033497 protein_coding_gene - - - CG12912 - CG12912 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031643 CG3008 - http://flybase.org/reports/FBgn0031643 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000687, InterPro:IPR017406 protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR000687, InterPro:IPR017406 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with SGD:S000005645" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000005645 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005645 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005645 CG3008 "IPR000687:RIO kinase, IPR011009:Protein kinase-like domain, IPR017406:Serine/threonine-protein kinase Rio3" CG3008 11-Aug-17 DroID_v2017_08 Drer\riok3 Scer\RIO1 Cele\riok-3 Xtro\riok3 Mmus\Riok3 Hsap\RIOK3 viable DRSC00560 I 1.853955276 0.044058262 0.205067846 0.01739177 0.082206766 0.184365511 FBgn0031613 HP6 Heterochromatin protein 6 http://flybase.org/reports/FBgn0031613 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95RV2 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with Su(var)205 female meiotic division ; GO:0007143 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from sequence or structural similarity with Su(var)205 "heterochromatin ; GO:0000792 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay chromatin ; GO:0000785 | inferred from sequence or structural similarity with Su(var)205 nucleolus ; GO:0005730 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay" "CG15636, HP6, Umbrea, umbrea, UMB, UMBREA" "IPR000953:Chromo/chromo shadow domain, IPR008251:Chromo shadow domain, IPR016197:Chromo domain-like" CG15636 11-Aug-17 DroID_v2017_08 "Drer\cbx1a, Drer\cdyl, Drer\cbx5, Drer\cbx1b, Drer\cbx3b, Drer\cbx3a" - "Cele\hpl-1, Cele\hpl-2, Cele\set-31, Cele\H04D03.6" "Xtro\cbx5, Xtro\cbx1, Xtro\cbx3" "Mmus\Cbx1, Mmus\Cdyl, Mmus\Cbx3, Mmus\Cbx5, Mmus\Mphosph8, Mmus\Cdyl2" "Hsap\CBX5, Hsap\CDY2A, Hsap\CDY1B, Hsap\MPHOSPH8, Hsap\CDY1, Hsap\CBX3, Hsap\CDY2B, Hsap\CDYL, Hsap\CBX1, Hsap\CDYL2" "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,neuroanatomy defective,viable,visible" "eye,polytene chromosome, telomeric regionG61,embryonic/larval salivary gland,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,polar body nucleus" FBgn0034705 CG11170 - http://flybase.org/reports/FBgn0034705 protein_coding_gene - regulation of signal transduction ; GO:0009966 | inferred from biological aspect of ancestor with PANTHER:PTN001279849 - "CG11170, CG30279" "IPR022049:FAM69, protein-kinase domain" CG11170 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-147f11.1, Drer\dia1b, Drer\dia1a" - - Xtro\c3orf58 "Mmus\4930578C19Rik, Mmus\1190002N15Rik" "Hsap\CXorf36, Hsap\C3orf58" viable FBgn0084432 Su(dpp)YE12 Su(dpp)YE12 http://flybase.org/reports/FBgn0084432 gene - - - Su(dpp)YE12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male sterile" FBgn0053373 5SrRNA:CR33373 5SrRNA:CR33373 http://flybase.org/reports/FBgn0053373 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33373, 5SrRNA:CR33373" - CR33373 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025378 CG3795 - http://flybase.org/reports/FBgn0025378 FBgn0063223 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "EG:9D2.4, SP160, BcDNA:GH24985, CG3795" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG3795 11-Aug-17 DroID_v2017_08 "Drer\cfd, Drer\gzma, Drer\si:dkeyp-93a5.3, Drer\si:dkey-16l2.17, Drer\zgc:165423, Drer\zgc:163079, Drer\ovch1, Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.9, Drer\si:ch211-165b19.8, Drer\zgc:92313, Drer\gzmk, Drer\LOC100004427, Drer\gzm3" - "Cele\try-1, Cele\try-6" - "Mmus\Klk15, Mmus\Klk9" "Hsap\KLK9, Hsap\KLK15" viable FBgn0026335 Su(tor)278-22 Su(tor)278-22 http://flybase.org/reports/FBgn0026335 - gene - - - Su(tor)278-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266426 Dfd::Scr Dfd::Scr http://flybase.org/reports/FBgn0266426 engineered_fusion_gene - - - "Dfd::Scr, Dfd[Scr]" - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic mesothoracic segment,embryonic metathoracic segment,denticle,ectopic,cirri" FBgn0083294 E(smoDN)198 Enhancer of smoDN 198 http://flybase.org/reports/FBgn0083294 gene - - - E(smoDN)198 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259446 C246 - http://flybase.org/reports/FBgn0259446 gene - - - C246 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing,chaeta" FBgn0263734 dco::Hsap\CSNK1E - http://flybase.org/reports/FBgn0263734 engineered_fusion_gene - - - "dco::Hsap\CSNK1E, ckIepsilon-dbt" - - 11-Aug-17 DroID_v2017_08 - - - - - - locomotor rhythm defective FBgn0052238 CG32238 - http://flybase.org/reports/FBgn0052238 protein_coding_gene - protein polyglutamylation ; GO:0018095 | inferred from electronic annotation with InterPro:IPR027750 - "CG32238, CG7474" "IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027750:Tubulin polyglutamylase TTLL1" CG32238 11-Aug-17 DroID_v2017_08 "Drer\ttll1, Drer\ttll2, Drer\ttll9, Drer\ttll5, Drer\ttll10, Drer\ttl" Scer\PBY1 "Cele\ttll-15, Cele\ttll-5, Cele\ttll-9, Cele\ttll-4" "Xtro\ttll2, Xtro\ttll3, Xtro\LOC100158544, Xtro\ttll5, Xtro\ttll1, Xtro\ttl" "Mmus\Ttll2, Mmus\Ttll3, Mmus\Ttll9, Mmus\Ttll10, Mmus\Ttll5, Mmus\Ttl, Mmus\Ttll1, Mmus\Ttll8" "Hsap\TTLL3, Hsap\TTLL5, Hsap\ARPC4-TTLL3, Hsap\TTLL9, Hsap\TTLL10, Hsap\TTLL8, Hsap\TTLL2, Hsap\TTL, Hsap\TTLL1" viable FBgn0000287 salr spalt-related http://flybase.org/reports/FBgn0000287 - protein_coding_gene "transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from sequence or structural similarity with WB:WBGene00004773 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000579295" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 antennal joint development ; GO:0048098 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 male genitalia development ; GO:0030539 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with WB:WBGene00004773 sensory perception of sound ; GO:0007605 | inferred from genetic interaction with salm neurogenesis ; GO:0022008 | inferred from mutant phenotype male gonad development ; GO:0008584 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000579295" nucleus ; GO:0005634 | inferred from sequence or structural similarity with WB:WBGene00004773 nucleus ; GO:0005634 | inferred from direct assay "spalt, sal, Spalt, sal-r, Sal-r, salR, 32F, Cf3, CG4881, salr, Salr" IPR013087:Zinc finger C2H2-type CG4881 11-Aug-17 DroID_v2017_08 "Drer\znf1004, Drer\sall3b, Drer\znf219, Drer\znf526, Drer\znf217, Drer\rreb1a, Drer\znf536, Drer\sall3a, Drer\sall2, Drer\si:ch211-212k18.5, Drer\sall1a, Drer\znf516, Drer\sall4, Drer\rreb1b, Drer\znf983, Drer\si:ch211-202h22.10, Drer\znf1010, Drer\LOC100537687, Drer\si:ch211-266d19.4" - "Cele\sem-4, Cele\Y48G8AL.10" "Xtro\znf568, Xtro\znf236, Xtro\sall3, Xtro\sall2, Xtro\znf208, Xtro\sall1, Xtro\sall4" "Mmus\Rbak, Mmus\Zfp235, Mmus\Zfp236, Mmus\Zfp458, Mmus\Sall1, Mmus\Zfp229, Mmus\Zfp74, Mmus\Zfp560, Mmus\Zfp182, Mmus\Rreb1, Mmus\Gm14432, Mmus\Sall2, Mmus\Zfp808, Mmus\Zfp27, Mmus\Zfp334, Mmus\Zfp217, Mmus\Zfp619, Mmus\Zfp536, Mmus\Zfp62, Mmus\Gm14124, Mmus\Zfp26, Mmus\Zfp516, Mmus\Zfp219, Mmus\Sall3, Mmus\Zfp709, Mmus\Sall4" "Hsap\ZNF268, Hsap\SALL4, Hsap\ZNF433, Hsap\ZNF585B, Hsap\SALL3, Hsap\ZNF775, Hsap\ZNF721, Hsap\ZNF699, Hsap\ZNF709, Hsap\ZNF717, Hsap\ZNF160, Hsap\ZNF536, Hsap\SALL2, Hsap\ZNF236, Hsap\ZNF227, Hsap\ZNF761, Hsap\ZNF234, Hsap\ZNF135, Hsap\ZNF226, Hsap\ZNF251, Hsap\ZNF107, Hsap\ZNF443, Hsap\ZNF182, Hsap\ZNF91, Hsap\ZFP62, Hsap\ZNF229, Hsap\ZNF516, Hsap\ZNF850, Hsap\ZNF217, Hsap\ZNF585A, Hsap\ZNF836, Hsap\HKR1, Hsap\RREB1, Hsap\ZNF235, Hsap\ZNF574, Hsap\SALL1, Hsap\ZNF337, Hsap\ZNF845, Hsap\ZNF219" " embryonic stage -- adult stage , larval stage | third instar " dorsal mesothoracic disc | restricted

" embryonic stage | stage 16 , embryonic stage | late , larval stage , larval stage | third instar " " embryonic/larval posterior spiracle

, embryonic central nervous system

, larval central nervous system

, dorsal mesothoracic disc | dorsal comparment & medial

, imaginal disc

, dorsal mesothoracic disc | restricted

" "visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "macrochaeta,ectopic,anterior dorsocentral bristle,anterior postalar bristle,precursor,posterior postalar bristle,anterior notopleural bristle,posterior notopleural bristle,dorsocentral bristle,notopleural bristle,postalar bristle,wing vein L2,wing vein L5,posterior dorsocentral bristle,posterior scutellar bristle,adult thorax & macrochaetaBx-MS1096,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,wing vein,wing" FBgn0002891 mus205 mutagen-sensitive 205 http://flybase.org/reports/FBgn0002891 FBgn0033223 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006134 nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR006134, InterPro:IPR006172, InterPro:IPR017964 3'-5' exonuclease activity ; GO:0008408 | NOT inferred from direct assay DNA-directed DNA polymerase activity ; GO:0003887 | inferred from direct assay" translesion synthesis ; GO:0019985 | non-traceable author statement double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype error-prone translesion synthesis ; GO:0042276 | inferred from biological aspect of ancestor with PANTHER:PTN000035411 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000035347 zeta DNA polymerase complex ; GO:0016035 | inferred from biological aspect of ancestor with PANTHER:PTN000035411 "154926_at, Dmpolzeta, CG1925, AAF59191, DmREV3, DhRev3, mus 205, mus-205, mus(2)205, mus205, Mus205, rev3" "IPR017964:DNA-directed DNA polymerase, family B, conserved site, IPR025687:C4-type zinc-finger of DNA polymerase delta, IPR006134:DNA-directed DNA polymerase, family B, multifunctional domain, IPR006172:DNA-directed DNA polymerase, family B, IPR012337:Ribonuclease H-like domain, IPR006133:DNA-directed DNA polymerase, family B, exonuclease domain, IPR023211:DNA polymerase, palm domain" CG1925 11-Aug-17 DroID_v2017_08 "Drer\pold1, Drer\si:ch211-134n22.1, Drer\si:dkey-114c15.7, Drer\rev3l" Scer\REV3 Cele\Y37B11A.2 "Xtro\pold1, Xtro\rev3l" "Mmus\Rev3l, Mmus\C77370, Mmus\Pold1" "Hsap\REV3L, Hsap\KIAA2022, Hsap\POLD1" "chemical sensitive,radiation sensitive,DNA repair defective,recessive,viable,radiation resistant,fertile,maternal effect,female fertile,reduced" FBgn0014202 l(1)16Fi lethal (1) 16Fi http://flybase.org/reports/FBgn0014202 - gene - - - l(1)16Fi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0004026 wtl weltlike http://flybase.org/reports/FBgn0004026 - gene - - - wtl - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "eye,arista,wing" FBgn0082343 HM515 HM515 http://flybase.org/reports/FBgn0082343 gene - - - HM515 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263073 GS5246 - http://flybase.org/reports/FBgn0263073 gene - - - GS5246 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002878 mus101 mutagen-sensitive 101 http://flybase.org/reports/FBgn0002878 FBgn0030515 protein_coding_gene - mitotic DNA replication checkpoint ; GO:0033314 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | traceable author statement oogenesis ; GO:0048477 | traceable author statement mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype inferred from genetic interaction with nbs DNA replication initiation ; GO:0006270 | inferred from biological aspect of ancestor with PANTHER:PTN000339409 - "DmMus101, anon-WO0148202.1, fs(1)K451, mus 101, mus(1)101, mus-101, CG11156, mus101, Mus101, TOPBP1" IPR001357:BRCT domain CG11156 11-Aug-17 DroID_v2017_08 "Drer\ect2, Drer\topbp1" Scer\DPB11 "Cele\ect-2, Cele\mus-101" "Xtro\ect2, Xtro\topbp1, Xtro\slf1" "Mmus\Ect2, Mmus\Slf1, Mmus\Topbp1" "Hsap\SLF1, Hsap\ECT2, Hsap\TOPBP1" embryonic stage | 0-4 hr "chemical sensitive,radiation sensitive,DNA repair defective,wild-type,lethal,recessive,female sterile,partially,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,female sterile germline-dependent,viable" "imaginal disc,mitosis & nuclear chromosome,heterochromatin,chromatin" FBgn0001054 Fs(3)Kar Female sterile (3) Kartal http://flybase.org/reports/FBgn0001054 - gene molecular_function ; GO:0003674 | no biological data available embryonic cleavage ; GO:0040016 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Kar, Fs(3)Kartal, Fs(3)Sz27, Fs(3)Kar" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cleavage stage embryo,maternal effect" FBgn0016737 SR3-7 SR3-7 http://flybase.org/reports/FBgn0016737 - gene - - - SR3-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265160 CR44229 - http://flybase.org/reports/FBgn0265160 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44229, CR44229" - CR44229 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060970 l(3)SzB90Co lethal (3) SzB90Co http://flybase.org/reports/FBgn0060970 gene - - - "0297/01, l(3)S029701b, l(3)SzB90Co" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263829 CG34334 - http://flybase.org/reports/FBgn0263829 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "CG34334, cg9561, CG9561" "IPR000504:RNA recognition motif domain, IPR034201:RNPS1, RNA recognition motif" CG34334 11-Aug-17 DroID_v2017_08 "Drer\srsf2b, Drer\pabpn1l, Drer\pabpn1, Drer\rnps1, Drer\srsf2a, Drer\LOC103909923" Scer\SGN1 "Cele\rnp-5, Cele\rsp-4" "Xtro\srsf2, Xtro\pabpn1, Xtro\rnps1, Xtro\pabpn1l" "Mmus\Pnn, Mmus\Pabpn1l, Mmus\Rnps1, Mmus\Srsf2, Mmus\Pabpn1, Mmus\Bcl2l2" "Hsap\RNPS1, Hsap\SRSF2, Hsap\BCL2L2, Hsap\BCL2L2-PABPN1, Hsap\PABPN1, Hsap\PABPN1L" FBgn0027630 ms(1)66 ms(1)66 http://flybase.org/reports/FBgn0027630 - gene - - - ms(1)66 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile meiosis I FBgn0032803 CG13082 - http://flybase.org/reports/FBgn0032803 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13082 - CG13082 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" trichogen cell FBgn0065900 l(2)SH0201 lethal (2) SH0201 http://flybase.org/reports/FBgn0065900 gene - - - l(2)SH0201 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002390 l(3)93Dg lethal (3) 93Dg http://flybase.org/reports/FBgn0002390 - gene - - - "er13, l(3)er13, l(3)93Dg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067778 els ellsworth http://flybase.org/reports/FBgn0067778 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available els - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "nurse cell,germline clone,oocyte,egg,embryonic head" FBgn0051017 PH4alphaNE3 prolyl-4-hydroxylase-alpha NE3 http://flybase.org/reports/FBgn0051017 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG9708, CG31017, PH4alphaNE3" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG31017 11-Aug-17 DroID_v2017_08 "Drer\zgc:158254, Drer\p4htm, Drer\p4ha2, Drer\p4ha1a, Drer\zgc:152670, Drer\p4ha1b, Drer\p4ha3" - "Cele\phy-4, Cele\Y43F8B.19, Cele\phy-2, Cele\phy-3, Cele\C14E2.4" "Xtro\p4ha2, Xtro\p4ha1, Xtro\p4ha3" "Mmus\P4ha3, Mmus\P4htm, Mmus\P4ha2, Mmus\P4ha1" "Hsap\P4HA2, Hsap\P4HA3, Hsap\P4HA1, Hsap\P4HTM" viable FBgn0001542 l(1)14Ea lethal (1) 14Ea http://flybase.org/reports/FBgn0001542 - gene - - - "l(1)k22a, k22a, l(1)14Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004513 Mdr65 Multi drug resistance 65 http://flybase.org/reports/FBgn0004513 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 efflux transmembrane transporter activity ; GO:0015562 | inferred from direct assay xenobiotic-transporting ATPase activity ; GO:0008559 | inferred from direct assay" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 establishment of glial blood-brain barrier ; GO:0060857 | inferred from direct assay renal tubular secretion ; GO:0097254 | inferred from expression pattern response to toxic substance ; GO:0009636 | inferred from expression pattern xenobiotic transport ; GO:0042908 | inferred from direct assay ATP-binding cassette (ABC) transporter complex ; GO:0043190 | inferred from direct assay pleated septate junction ; GO:0005919 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "Mdr65A, CG10181, Mdr65, mdr65, MDR65, P-gp, P-glycoprotein" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10181 11-Aug-17 DroID_v2017_08 "Drer\abcb4, Drer\abcb8, Drer\abcb3l1, Drer\abcb11a, Drer\abcb11b, Drer\abcb10, Drer\abcb9, Drer\abcb5" Scer\STE6 "Cele\pgp-5, Cele\haf-4, Cele\haf-8, Cele\haf-1, Cele\pgp-7, Cele\pgp-9, Cele\haf-6, Cele\pgp-1, Cele\pgp-4, Cele\haf-2, Cele\pgp-10, Cele\haf-3, Cele\pgp-8, Cele\pgp-6, Cele\pgp-14, Cele\pgp-12, Cele\pgp-3, Cele\pgp-2, Cele\haf-7, Cele\pgp-13, Cele\pgp-11, Cele\haf-9" "Xtro\abcb8, Xtro\LOC100494740" "Mmus\Abcb9, Mmus\Abcb11, Mmus\Abcb1a, Mmus\Abcb10, Mmus\Abcb4, Mmus\Abcb5, Mmus\Abcb8, Mmus\Abcb1b" "Hsap\ABCB11, Hsap\ABCB4, Hsap\ABCB8, Hsap\ABCB5, Hsap\ABCB1, Hsap\ABCB10" viable FBgn0036531 CG6244 - http://flybase.org/reports/FBgn0036531 protein_coding_gene RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 transcription elongation factor complex ; GO:0008023 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 CG6244 IPR007808:Transcription elongation factor 1 CG6244 11-Aug-17 DroID_v2017_08 Drer\elof1 Scer\ELF1 Cele\Y54G11A.11 Xtro\elof1 "Mmus\Elof1, Mmus\Gm36718" Hsap\ELOF1 FBgn0030907 CG15058 - http://flybase.org/reports/FBgn0030907 protein_coding_gene - - - CG15058 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029100 anon-89Bc anon-89Bc http://flybase.org/reports/FBgn0029100 gene - - - anon-89Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065734 l(2)SH0545 lethal (2) SH0545 http://flybase.org/reports/FBgn0065734 gene - - - "l(2)SH0545, l(2)SH2 0545" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014880 Sry-beta::Sry-delta Sry-beta::Sry-delta http://flybase.org/reports/FBgn0014880 - engineered_fusion_gene - - - Sry-beta::Sry-delta - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0058139 CG40139 - http://flybase.org/reports/FBgn0058139 protein_coding_gene - - - CG40139 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032554 CG15278 - http://flybase.org/reports/FBgn0032554 protein_coding_gene - - - "bs32h08.y1, NEST:bs32h08, CG15278" - CG15278 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037252 CG14650 - http://flybase.org/reports/FBgn0037252 protein_coding_gene - - - CG14650 "IPR001623:DnaJ domain, IPR032843:Cleavage inducing molecular chaperone, Jiv" CG14650 11-Aug-17 DroID_v2017_08 Drer\dnajc14 Scer\HLJ1 Cele\dnj-5 Xtro\dnajc14 Mmus\Dnajc14 Hsap\DNAJC14 viable FBgn0263084 HP1Lcsd Heterochromatin Protein 1L chromoshadow domain http://flybase.org/reports/FBgn0263084 protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with Su(var)205 chromosome organization ; GO:0051276 | inferred from sequence or structural similarity with Su(var)205 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008251 chromatin ; GO:0000785 | inferred from sequence or structural similarity with Su(var)205 "HP1Lcsd, lincRNA.384, CG43352" "IPR016197:Chromo domain-like, IPR008251:Chromo shadow domain" CG43352 11-Aug-17 DroID_v2017_08 "Drer\cbx5, Drer\cbx1b, Drer\cbx1a" - - - "Mmus\Cbx5, Mmus\Cbx1" "Hsap\CBX1, Hsap\CBX5" FBgn0260320 GSd404 - http://flybase.org/reports/FBgn0260320 gene - - - GSd404 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "intersegmental nerve,segmental nerve" FBgn0031644 CG15625 - http://flybase.org/reports/FBgn0031644 protein_coding_gene - - - CG15625 "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG15625 11-Aug-17 DroID_v2017_08 - - - - Mmus\Samd15 Hsap\SAMD15 "viable,fertile" FBgn0264912 CR44103 - http://flybase.org/reports/FBgn0264912 non_protein_coding_gene - - - "CR44103, lincRNA.679" - CR44103 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027262 l(1)G0228 lethal (1) G0228 http://flybase.org/reports/FBgn0027262 - gene - - - l(1)G0228 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" adult abdomen FBgn0020857 fs(2)261404 female sterile(2)261404 http://flybase.org/reports/FBgn0020857 - gene - - - "fs(2)A, fs(2)261404" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0260800 l(2)GSG317 - http://flybase.org/reports/FBgn0260800 gene - - - l(2)GSG317 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034671 CG13494 - http://flybase.org/reports/FBgn0034671 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT17606, CG13494" - CG13494 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0014869 Pglym78 Phosphoglyceromutase http://flybase.org/reports/FBgn0014869 - protein_coding_gene "2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity ; GO:0046538 | inferred from biological aspect of ancestor with PANTHER:PTN000231842" regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 regulation of pentose-phosphate shunt ; GO:0043456 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 myoblast fusion ; GO:0007520 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype gluconeogenesis ; GO:0006094 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 Z disc ; GO:0030018 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 M band ; GO:0031430 | inferred from direct assay "PGAM, Pglym, CG1721, Pglym78, PGLYM, pglym78" "IPR001345:Phosphoglycerate/bisphosphoglycerate mutase, active site, IPR005952:Phosphoglycerate mutase 1, IPR013078:Histidine phosphatase superfamily, clade-1, IPR029033:Histidine phosphatase superfamily" CG1721 11-Aug-17 DroID_v2017_08 "Drer\pgam1b, Drer\bpgm, Drer\pgam2, Drer\pgam1a, Drer\tigara" "Scer\GPM1, Scer\GPM2, Scer\GPM3" - "Xtro\pgam1, Xtro\bpgm, Xtro\pgam2" "Mmus\Bpgm, Mmus\Pgam2, Mmus\Pgam1" "Hsap\BPGM, Hsap\PGAM1, Hsap\PGAM2, Hsap\PGAM4" "embryonic/larval somatic muscle,embryonic myoblast,segment border muscle,A1-7 dorsal acute muscle 1" FBgn0011646 Low Lightener of white http://flybase.org/reports/FBgn0011646 - gene - - - Low - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" pigment cell FBgn0019810 ftz::RpP1 ftz::RpP1 http://flybase.org/reports/FBgn0019810 - engineered_fusion_gene - - - "ftz::RpA-70, ftz::RpP1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013595 l(3)A6-3-56 lethal (3) A6-3-56 http://flybase.org/reports/FBgn0013595 - gene - - - l(3)A6-3-56 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028411 Nxt1 NTF2-related export protein 1 http://flybase.org/reports/FBgn0028411 protein_coding_gene - negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "p15, Nxt, dmP15, dNxt, DmNXT1, dmNXT1, nxt1, CG12752, Nxt1, dmNXT" "IPR018222:Nuclear transport factor 2, eukaryote, IPR002075:Nuclear transport factor 2, IPR032710:NTF2-like domain" CG12752 11-Aug-17 DroID_v2017_08 Drer\nxt2 "Scer\MTR2, Scer\NTF2" Cele\nxt-1 Xtro\nxt2 "Mmus\Nxt1, Mmus\Nxt2" "Hsap\NXT1, Hsap\NXT2" "visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" mesothoracic tergum DRSC04630 I 2.127790577 -0.39622592 -0.673188721 1.417723194 0.176290143 0.803750775 FBgn0023034 l(2)46Ei lethal (2) 46Ei http://flybase.org/reports/FBgn0023034 - gene - - - "S, l(2)46Ei" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,some die during larval stage" FBgn0261111 BHD Birt-Hogg-Dube http://flybase.org/reports/FBgn0261111 protein_coding_gene guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from electronic annotation with InterPro:IPR032035 molecular_function ; GO:0003674 | no biological data available germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding ; GO:1901840 | inferred from direct assay negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter ; GO:1901837 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "DBHD, BHD, CG8616, CT25610, dFLCN" "IPR021713:Folliculin, IPR032035:Folliculin, C-terminal" CG8616 11-Aug-17 DroID_v2017_08 Drer\flcn Scer\LST7 Cele\flcn-1 Xtro\flcn Mmus\Flcn Hsap\FLCN FBgn0266670 Sec5 Secretory 5 http://flybase.org/reports/FBgn0266670 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab30 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab11 "transcytosis ; GO:0045056 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype protein localization to cell cortex ; GO:0072697 | inferred from mutant phenotype Golgi to plasma membrane transport ; GO:0006893 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype synaptic vesicle targeting ; GO:0016080 | non-traceable author statement innate immune response ; GO:0045087 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | non-traceable author statement positive regulation of Golgi vesicle fusion to target membrane ; GO:0048215 | inferred from mutant phenotype protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype synaptic vesicle docking ; GO:0016081 | non-traceable author statement exocyst assembly ; GO:0001927 | inferred from biological aspect of ancestor with PANTHER:PTN000315823 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype Golgi to plasma membrane protein transport ; GO:0043001 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype protein localization to adherens junction ; GO:0071896 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype" cell cortex ; GO:0005938 | inferred from direct assay annulate lamellae ; GO:0005642 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay exocyst ; GO:0000145 | inferred from direct assay exocyst ; GO:0000145 | inferred from biological aspect of ancestor with PANTHER:PTN000315823 exocyst ; GO:0000145 | non-traceable author statement exocyst ; GO:0000145 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay clathrin-coated vesicle ; GO:0030136 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay subapical complex ; GO:0035003 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay "sec5, Sec5, SEC5, Sec-5, Sec5p, dsec5, CG8843" "IPR002909:IPT domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR029175:Exocyst complex component EXOC2/Sec5" CG8843 11-Aug-17 DroID_v2017_08 Drer\exoc2 Scer\SEC5 Cele\sec-5 Xtro\exoc2 Mmus\Exoc2 Hsap\EXOC2 FBgn0021789 l(2)rH280 lethal (2) rH280 http://flybase.org/reports/FBgn0021789 - gene - - - l(2)rH280 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069071 zih ziehharmonika http://flybase.org/reports/FBgn0069071 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available zih - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect,filzkorper,embryonic segment" FBgn0032472 CG9928 - http://flybase.org/reports/FBgn0032472 protein_coding_gene - - - "CT27834, BcDNA:RH70154, CG9928" - CG9928 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0067056 Q7 Q7 http://flybase.org/reports/FBgn0067056 gene - - - Q7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,viable" eye FBgn0031410 CG17237 - http://flybase.org/reports/FBgn0031410 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" - myosin complex ; GO:0016459 | inferred from sequence or structural similarity "DmAAF51272, BcDNA:AT15471, CG17237, ELC4" IPR011992:EF-hand domain pair CG17237 11-Aug-17 DroID_v2017_08 "Drer\mylz3, Drer\cmlc1, Drer\zgc:153867, Drer\zgc:163073, Drer\myl4, Drer\myl13, Drer\myl6, Drer\myl1" Scer\MLC1 "Cele\cal-7, Cele\mlc-5, Cele\mlc-7, Cele\mlc-6" "Xtro\myl1, Xtro\myl4, Xtro\myl3, Xtro\myl6" "Mmus\Myl3, Mmus\Myl6, Mmus\Myl1, Mmus\Myl4, Mmus\Myl6b" "Hsap\MYL3, Hsap\MYL1, Hsap\MYL6, Hsap\MYL6B, Hsap\MYL4" FBgn0065614 l(2)SH0824 lethal (2) SH0824 http://flybase.org/reports/FBgn0065614 gene - - - "l(2)SH0824, l(2)SH2 0824" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264090 CG43759 - http://flybase.org/reports/FBgn0264090 protein_coding_gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - "CG43759, CG32541, CG14188, EP(X)1644, LD15404, CG12527, CG42506" - CG43759 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066292 CheB42c Chemosensory protein B 42c http://flybase.org/reports/FBgn0066292 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CG15241, CG33350, CheB42c" "IPR010512:Protein of unknown function DUF1091, IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG33350 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal" FBgn0023058 l(1)2Ed lethal (1) 2Ed http://flybase.org/reports/FBgn0023058 - gene - - - "E3/34.12, l(1)2Ed" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000656 fil fine lash http://flybase.org/reports/FBgn0000656 - gene - - - fil - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" "macrochaeta,eye" FBgn0266861 CR45322 - http://flybase.org/reports/FBgn0266861 non_protein_coding_gene - - - CR45322 - CR45322 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032374 CG14931 - http://flybase.org/reports/FBgn0032374 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14931 - CG14931 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035484 CG11594 - http://flybase.org/reports/FBgn0035484 protein_coding_gene "phosphotransferase activity, alcohol group as acceptor ; GO:0016773 | inferred from electronic annotation with InterPro:IPR000577, InterPro:IPR006003, InterPro:IPR018484, InterPro:IPR018485" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000577, InterPro:IPR006003, InterPro:IPR018484, InterPro:IPR018485 response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype" - CG11594 "IPR006003:FGGY carbohydrate kinase, pentulose kinase, IPR018485:Carbohydrate kinase, FGGY, C-terminal, IPR018484:Carbohydrate kinase, FGGY, N-terminal, IPR000577:Carbohydrate kinase, FGGY" CG11594 11-Aug-17 DroID_v2017_08 Drer\fggy "Scer\YDR109C, Scer\MPA43" - Xtro\fggy Mmus\Fggy Hsap\FGGY viable FBgn0030519 CG11151 - http://flybase.org/reports/FBgn0030519 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence model peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000009767 "2, CG11151" IPR003033:SCP2 sterol-binding domain CG11151 11-Aug-17 DroID_v2017_08 "Drer\scp2b, Drer\hsd17b4" Scer\FOX2 "Cele\dhrs-4, Cele\maoc-1, Cele\nlt-1, Cele\dhs-28" Xtro\hsd17b4 "Mmus\Hsd17b4, Mmus\Scp2d1" "Hsap\SCP2D1, Hsap\HSD17B4" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC19387 I 2.264954329 -0.438673305 -0.114434953 0.435375769 -1.119534833 0.781024737 FBgn0005678 mcd1 muscle cell death 1 http://flybase.org/reports/FBgn0005678 - gene - - - "mcd-1, mcd1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "muscle 18a,maternal effect,muscle 18b" FBgn0013521 l(1)x lethal (1) x http://flybase.org/reports/FBgn0013521 - gene - - - "l(x), l(1)x" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065756 l(2)SH0488 lethal (2) SH0488 http://flybase.org/reports/FBgn0065756 gene - - - "l(2)SH0488, l(2)SH2 0488" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022367 Pt-6 Larval protein-6 http://flybase.org/reports/FBgn0022367 - gene - - - Pt-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260287 GSd451 - http://flybase.org/reports/FBgn0260287 gene - - - GSd451 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034664 CG4377 - http://flybase.org/reports/FBgn0034664 protein_coding_gene - - - "CT14296, CG4377" IPR008472:Domain of unknown function DUF753 CG4377 11-Aug-17 DroID_v2017_08 - - "Cele\F55B11.4, Cele\D1081.6, Cele\C54D10.13, Cele\ZK757.10" - "Mmus\Ly6d, Mmus\Lynx1, Mmus\Slurp2, Mmus\2010109I03Rik" "Hsap\LYNX1, Hsap\LY6D" viable FBgn0023066 l(1)20BFa lethal (1) 20BFa http://flybase.org/reports/FBgn0023066 - gene - - - "400C20a, l(1)20BFa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013268 Eip4F Eip4F http://flybase.org/reports/FBgn0013268 - gene - - - "4F, Eip4F" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060773 l(3)S061308 lethal (3) S061308 http://flybase.org/reports/FBgn0060773 gene - - - "0613/08, l(3)S061308" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal" FBgn0040707 CG15430 - http://flybase.org/reports/FBgn0040707 protein_coding_gene - - - CG15430 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034052 CG8299 - http://flybase.org/reports/FBgn0034052 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP65, CG8299" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG8299 11-Aug-17 DroID_v2017_08 "Drer\LOC560023, Drer\zmp:0000001088, Drer\si:dkey-33m11.8" - "Cele\try-1, Cele\svh-1" - "Mmus\Prss47, Mmus\Prss36, Mmus\Prss53" "Hsap\PRSS36, Hsap\PRSS53" viable FBgn0259297 EP-232 - http://flybase.org/reports/FBgn0259297 gene - - - EP-232 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing" FBgn0015481 l(2)45Cb lethal (2) 45Cb http://flybase.org/reports/FBgn0015481 - gene - - - l(2)45Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0045852 ham hamlet http://flybase.org/reports/FBgn0045852 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype" "dendrite morphogenesis ; GO:0048813 | traceable author statement neuroblast fate commitment ; GO:0014017 | inferred from mutant phenotype regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype" nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "CG15906, CG10568, CG31753, CG15907, ham, Ham, HAM_DROME, hamlet" "IPR013087:Zinc finger C2H2-type, IPR030413:Evi1/Prdm16, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31753 11-Aug-17 DroID_v2017_08 "Drer\mecom, Drer\znf1010, Drer\znf1015, Drer\si:ch211-263k4.2, Drer\znf1004" "Scer\MSN2, Scer\MSN4, Scer\COM2" "Cele\zag-1, Cele\egl-43" "Xtro\klf17, Xtro\znf850, Xtro\znf180" "Mmus\Zfp442, Mmus\Prdm16, Mmus\AU041133, Mmus\Zfp617, Mmus\Zfp729a, Mmus\Zfp27, Mmus\Zfp62, Mmus\Zfp316, Mmus\Gli1, Mmus\Zfp26, Mmus\Zfp112, Mmus\Klf11, Mmus\Klf10, Mmus\Mecom, Mmus\Zfp619, Mmus\Zfp808, Mmus\Zfp236" "Hsap\ZNF85, Hsap\ZNF605, Hsap\ZNF808, Hsap\ZFP62, Hsap\ZNF721, Hsap\ZNF107, Hsap\ZNF883, Hsap\MECOM, Hsap\ZNF160, Hsap\ZNF91, Hsap\ZNF260, Hsap\PRDM16, Hsap\ZNF99, Hsap\ZNF211, Hsap\ZNF628, Hsap\ZNF208, Hsap\ZNF850, Hsap\ZNF676, Hsap\ZNF624, Hsap\ZNF587, Hsap\ZNF841, Hsap\ZNF836, Hsap\ZNF347, Hsap\ZNF696, Hsap\ZNF236, Hsap\KLF10, Hsap\ZNF780B, Hsap\ZNF658, Hsap\ZNF729" "viable,neuroanatomy defective,visible,decreased cell number,decreased cell size" "multidendritic neuron,supernumerary,dorsal abdominal cluster,eo neuron,trichogen cell,ectopic,tormogen cell,somatic clone,embryonic/larval nervous system,abdominal ventral sensillum campaniformium vc4a,secondary neuroblast,chaeta,type II neuroblast,type I neuroblast,ganglion mother cell" DRSC02070 K 0.544462478 0.908231016 -0.347781259 0.546755864 1.575814222 0.329884486 FBgn0039238 CG7016 - http://flybase.org/reports/FBgn0039238 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7016 - CG7016 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0082351 HM385 HM385 http://flybase.org/reports/FBgn0082351 gene - - - HM385 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262685 CG43155 - http://flybase.org/reports/FBgn0262685 protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" "CG43155, CG1756, CG15194, anon-WO0109301.9, anon-WO0109301.52, anon-WO0109301.51" "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG43155 11-Aug-17 DroID_v2017_08 "Drer\kcnk6, Drer\kcnk18, Drer\kcnk1b, Drer\kcnk10a, Drer\kcnk3a, Drer\kcnk7, Drer\kcnk10b, Drer\kcnk1a, Drer\kcnk15, Drer\kcnk2a, Drer\kcnk5a, Drer\kcnk9, Drer\kcnk5b, Drer\kcnk3b" "Scer\CTF3, Scer\TOK1" "Cele\twk-30, Cele\twk-3, Cele\twk-23, Cele\twk-46, Cele\twk-47, Cele\unc-58, Cele\twk-28, Cele\twk-32, Cele\twk-17, Cele\twk-7, Cele\twk-43, Cele\twk-2, Cele\twk-5, Cele\twk-29, Cele\twk-16, Cele\twk-10, Cele\egl-23, Cele\twk-20, Cele\twk-13, Cele\twk-37, Cele\sup-9, Cele\twk-4, Cele\twk-9, Cele\twk-40" "Xtro\kcnk18, Xtro\kcnk16, Xtro\LOC100486031, Xtro\kcnk7, Xtro\kcnk1, Xtro\kcnk6, Xtro\kcnk2, Xtro\kcnk4, Xtro\kcnk10, Xtro\kcnk5" "Mmus\Kcnk9, Mmus\Kcnk1, Mmus\Kcnk2, Mmus\Kcnk10, Mmus\Kcnk16, Mmus\Kcnk7, Mmus\Kcnk3, Mmus\Kcnk18, Mmus\Kcnk4, Mmus\Kcnk5, Mmus\Kcnk15, Mmus\Kcnk6" "Hsap\KCNK15, Hsap\KCNK2, Hsap\KCNK5, Hsap\KCNK9, Hsap\KCNK1, Hsap\BCL2, Hsap\KCNK6, Hsap\KCNK7, Hsap\KCNK17, Hsap\KCNK16, Hsap\KCNK3, Hsap\KCNK4, Hsap\KCNK10, Hsap\KCNK18" DRSC19777 K 0.856439848 0.672049348 -0.083395298 0.06439373 0.615555262 -1.797781903 FBgn0084019 CG41457 - http://flybase.org/reports/FBgn0084019 protein_coding_gene - - - CG41457 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036602 CG13042 - http://flybase.org/reports/FBgn0036602 protein_coding_gene - - - CG13042 IPR007614:Retinin-like protein CG13042 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011815 mei-269 mei-269 http://flybase.org/reports/FBgn0011815 - gene - - - mei-269 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060386 l(3)S134306a lethal (3) S134306a http://flybase.org/reports/FBgn0060386 gene - - - "1343/06, l(3)S134306a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027608 CG2082 - http://flybase.org/reports/FBgn0027608 - protein_coding_gene - - - "BcDNA:GH02439, CG2082" "IPR004142:NDRG, IPR029058:Alpha/Beta hydrolase fold" CG2082 11-Aug-17 DroID_v2017_08 "Drer\ndrg1a, Drer\ndrg2, Drer\ndrg4, Drer\ndrg3a, Drer\ndrg3b, Drer\ndrg1b" - "Cele\ZK1073.1, Cele\Y48G10A.3" "Xtro\ndrg2, Xtro\ndrg3, Xtro\ndrg1, Xtro\ndrg4" "Mmus\Ndrg4, Mmus\Ndrg2, Mmus\Ndrg3, Mmus\Ndrg1" "Hsap\NDRG4, Hsap\NDRG1, Hsap\NDRG3, Hsap\NDRG2" "viable,fertile,partially lethal - majority die" DRSC12125 E 0.014805064 0.822488474 3.187014626 0.687041031 -0.885840314 -0.544545221 FBgn0024224 ird10 immune response deficient 10 http://flybase.org/reports/FBgn0024224 - gene - positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype - "ird, ird10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033735 CG8525 - http://flybase.org/reports/FBgn0033735 protein_coding_gene deoxyribose-phosphate aldolase activity ; GO:0004139 | inferred from biological aspect of ancestor with PANTHER:PTN000095292 carbohydrate catabolic process ; GO:0016052 | inferred from biological aspect of ancestor with PANTHER:PTN000095292 deoxyribonucleotide catabolic process ; GO:0009264 | inferred from biological aspect of ancestor with PANTHER:PTN000095292 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011343 CG8525 "IPR002915:DeoC/FbaB/ lacD aldolase, IPR011343:Deoxyribose-phosphate aldolase, IPR013785:Aldolase-type TIM barrel" CG8525 11-Aug-17 DroID_v2017_08 Drer\dera - Cele\F09E5.3 Xtro\dera Mmus\Dera Hsap\DERA "viable,fertile" FBgn0035346 CG1146 - http://flybase.org/reports/FBgn0035346 protein_coding_gene - - - CG1146 - CG1146 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08189 E 0.732530614 0.410930236 -0.056289523 1.517949701 -0.018094121 -0.701037578 FBgn0267941 CR46221 - http://flybase.org/reports/FBgn0267941 non_protein_coding_gene - - - "CR46221, lincRNA.688" - CR46221 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065684 l(2)SH0660 lethal (2) SH0660 http://flybase.org/reports/FBgn0065684 gene - - - "l(2)SH0660, l(2)SH2 0660" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085350 inaF-C inaF-C http://flybase.org/reports/FBgn0085350 protein_coding_gene channel regulator activity ; GO:0016247 | inferred from sequence or structural similarity with inaF-B regulation of membrane potential ; GO:0042391 | inferred from sequence or structural similarity with inaF-B membrane ; GO:0016020 | inferred from sequence or structural similarity with inaF-B "inaF-C, CG34321, inaF, INAF, InaF" "IPR029162:TRP-interacting helix, InaF motif" CG34321 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034623 CG9822 - http://flybase.org/reports/FBgn0034623 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG9822, Agr-like" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG9822 11-Aug-17 DroID_v2017_08 "Drer\LOC101883528, Drer\pi15a, Drer\pi15b, Drer\r3hdml, Drer\crispld1b, Drer\glipr2l, Drer\crispld1a, Drer\glipr1b, Drer\glipr2, Drer\LOC100536500, Drer\crispld2" "Scer\PRY3, Scer\PRY1, Scer\PRY2" "Cele\scl-21, Cele\scl-5, Cele\scl-12, Cele\scl-9, Cele\scl-20, Cele\scl-15, Cele\scl-8, Cele\scl-17, Cele\scl-27, Cele\scl-2, Cele\scl-3, Cele\scl-23, Cele\scl-1, Cele\scl-19, Cele\scl-18, Cele\scl-13, Cele\scl-11, Cele\scl-10, Cele\scl-7, Cele\scl-14, Cele\scl-6" "Xtro\crispld2, Xtro\r3hdml, Xtro\MGC108118, Xtro\crisp2, Xtro\crisp1, Xtro\glipr2, Xtro\pi15, Xtro\crisp3" "Mmus\Pi15, Mmus\R3hdml, Mmus\Crisp2, Mmus\Pi16, Mmus\Clec18a, Mmus\Crispld1, Mmus\Glipr1l1, Mmus\Glipr1, Mmus\Crispld2, Mmus\Glipr2, Mmus\Glipr1l2, Mmus\Crisp4, Mmus\Crisp3, Mmus\Crisp1" "Hsap\CLEC18B, Hsap\CRISPLD1, Hsap\GLIPR1L1, Hsap\PI15, Hsap\PI16, Hsap\CRISPLD2, Hsap\CRISP1, Hsap\CLEC18C, Hsap\R3HDML, Hsap\CLEC18A, Hsap\GLIPR2, Hsap\CRISP2, Hsap\GLIPR1L2, Hsap\GLIPR1" viable FBgn0001342 l(1)1Bk lethal (1) 1Bk http://flybase.org/reports/FBgn0001342 - gene - - - "HM441, l(1)1Bk" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , embryonic stage " "wild-type,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025494 l(3)82CDc lethal (3) 82CDc http://flybase.org/reports/FBgn0025494 - gene - - - l(3)82CDc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable" FBgn0083001 snoRNA:Psi28S-1192a snoRNA:Psi28S-1192a http://flybase.org/reports/FBgn0083001 snoRNA_gene - - - "snoRNA:Psi28S-1192a, Psi28S-1192a, psi28S-1192a, Psi 28S-1192a, CR34597" - CR34597 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260002 snoRNA:Me28S-U2134b - http://flybase.org/reports/FBgn0260002 snoRNA_gene - - - "snoRNA:Me28S-U2134b, Me28S-Um2134b, CR34679, snoRNA:U34" - CR34679 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037291 CG14662 - http://flybase.org/reports/FBgn0037291 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT34440, CG14662" "IPR032675:Leucine-rich repeat domain, L domain-like" CG14662 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266133 c105 - http://flybase.org/reports/FBgn0266133 gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - c105 - - 11-Aug-17 DroID_v2017_08 - - - - - - gravitaxis defective FBgn0023120 anon-10An anon-10An http://flybase.org/reports/FBgn0023120 - gene - - - "6, anon-10An" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015935 eg-1 eg-1 http://flybase.org/reports/FBgn0015935 - gene - - - eg-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052022 CG32022 - http://flybase.org/reports/FBgn0052022 protein_coding_gene - tail-anchored membrane protein insertion into ER membrane ; GO:0071816 | inferred from electronic annotation with InterPro:IPR028945 oogenesis ; GO:0048477 | inferred from mutant phenotype - "CG5950, BcDNA:AT11343, CG32022, Chd5, Wrb" IPR028945:WRB/Get1 family CG32022 11-Aug-17 DroID_v2017_08 Drer\wrb Scer\GET1 Cele\wrb-1 Xtro\wrb Mmus\Wrb Hsap\WRB viable "nurse cell,germline clone,ring canal" FBgn0085430 CG34401 - http://flybase.org/reports/FBgn0085430 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007527 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG34401, CG17757, CG7307, CG7317, CG15037, CG32542" "IPR007527:Zinc finger, SWIM-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011990:Tetratricopeptide-like helical domain" CG34401 11-Aug-17 DroID_v2017_08 "Drer\zswim8, Drer\zswim5, Drer\zswim6" - Cele\ebax-1 "Xtro\zswim4, Xtro\zswim6, Xtro\zswim5, Xtro\zswim8" "Mmus\Zswim5, Mmus\Zswim6, Mmus\Zswim4, Mmus\Zswim8" "Hsap\ZSWIM8, Hsap\ZSWIM5, Hsap\ZSWIM6, Hsap\ZSWIM4" FBgn0051855 CG31855 - http://flybase.org/reports/FBgn0051855 protein_coding_gene - regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032434 | inferred from electronic annotation with InterPro:IPR033575 - "CG6537, CG31855" "IPR018276:DET1- and DDB1-associated protein 1, N-terminal, IPR033575:DET1- and DDB1-associated protein 1" CG31855 11-Aug-17 DroID_v2017_08 Drer\dda1 - Cele\F48C1.5 Xtro\dda1 Mmus\Dda1 Hsap\DDA1 viable DRSC02968 IK -1.499167095 -1.52824462 -0.10632783 0.163934937 -0.713775287 -1.672948211 FBgn0044065 GT7-45 GT7-45 http://flybase.org/reports/FBgn0044065 gene - - - GT7-45 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023415 Acp32CD Accessory gland protein 32CD http://flybase.org/reports/FBgn0023415 - protein_coding_gene hormone activity ; GO:0005179 | non-traceable author statement "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of female receptivity, post-mating ; GO:0045434 | non-traceable author statement" extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | traceable author statement extracellular region ; GO:0005576 | inferred from sequence model "CG4605, Acp32CD" - CG4605 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028552 gammaSnap1 gamma Soluble NSF attachment protein 1 http://flybase.org/reports/FBgn0028552 protein_coding_gene soluble NSF attachment protein activity ; GO:0005483 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 soluble NSF attachment protein activity ; GO:0005483 | non-traceable author statement syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 "membrane fusion ; GO:0061025 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 synaptic vesicle priming ; GO:0016082 | non-traceable author statement intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 neurotransmitter secretion ; GO:0007269 | non-traceable author statement wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap regulation of cell cycle ; GO:0051726 | inferred from direct assay" vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 cytoplasm ; GO:0005737 | non-traceable author statement SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay "gamma SNAP, gammaSnap, gamma-SNAP, CG3988, gammaSNAP-2, gSnap, gamma-Snap, gammaSnap1" "IPR000744:NSF attachment protein, IPR011990:Tetratricopeptide-like helical domain" CG3988 11-Aug-17 DroID_v2017_08 "Drer\napg, Drer\napga" - "Cele\Y59A8B.25, Cele\Y59A8B.8" Xtro\napg Mmus\Napg Hsap\NAPG viable DRSC04686 E 0.541054403 0.451811215 1.866366196 0.450903514 -0.302287334 -0.218194556 FBgn0036583 CG13055 - http://flybase.org/reports/FBgn0036583 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13055 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR032050:Domain of unknown function DUF4797" CG13055 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0045460 MCP-PRE MCP Polycomb group response element http://flybase.org/reports/FBgn0045460 regulatory_region - - - "MCP, Mcp, MCP-PRE, PRE, mcp, Mcp PRE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002724 mex Malic enzyme modifier http://flybase.org/reports/FBgn0002724 - gene - - - "Mex, mex" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065177 l(3)SH009 lethal (3) SH009 http://flybase.org/reports/FBgn0065177 gene - - - "l(3)SH009, l(2)SH3 009" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000360 Cp38 Chorion protein 38 http://flybase.org/reports/FBgn0000360 FBgn0004940 protein_coding_gene - - - "Cp38, CG11213, CP38, Dms38, S38, s38-1, s38, E3, ACE1, cp38" IPR008449:Chorion S36/S38 CG11213 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && oogenesis stage | stage >=S10B , oogenesis stage | stage S10-14 " follicle cell

adult stage | female " ovary

{ v fs(1)A1059K1 } , ovary

{ 0 swa6 } , ovary

, ovary

{ v mus101K451 } " "electrophoretic variant,viable" FBgn0001199 His3 Histone H3 http://flybase.org/reports/FBgn0001199 FBgn0062243 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000164, InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072" - RCAF complex ; GO:0035059 | inferred from direct assay nucleosome ; GO:0000786 | traceable author statement polytene chromosome ; GO:0005700 | inferred from direct assay nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR000164 nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay condensed nuclear chromosome ; GO:0000794 | "H3, histone H3, PH3, pH3, Ph3, his3, HisC, dH3, His, DmeH3, H3.1, anon-WO0118547.10, His3, histone, his, P~H3, DmH3, H3.3, HH3, phosph-H3, H[[3]], His3.2, h3, H3/H3.2, H3K9, Histone H3" "IPR000164:Histone H3/CENP-A, IPR007125:Histone H2A/H2B/H3, IPR009072:Histone-fold" - 11-Aug-17 DroID_v2017_08 - - - - - - spermatogenesis && adult stage " Y chromosome loop

, spermatid

, protein body

, spermatocyte

" "lethal - all die before end of embryonic stage,homeotic,somatic clone" FBgn0262855 CG43219 - http://flybase.org/reports/FBgn0262855 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43219, DMG4-MB6.chr3L.36.014" - CG43219 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085743 CR40560 - http://flybase.org/reports/FBgn0085743 rRNA_gene - - - CR40560 - CR40560 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062273 G192 G192 http://flybase.org/reports/FBgn0062273 gene - - - G192 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039727 Vps13B Vacuolar protein sorting 13B http://flybase.org/reports/FBgn0039727 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein targeting to vacuole ; GO:0006623 | inferred from sequence or structural similarity with SGD:S000003963 extrinsic component of membrane ; GO:0019898 | inferred from sequence or structural similarity with SGD:S000003963 "Vps13B, CG15523" "IPR026847:Vacuolar protein sorting-associated protein 13, IPR026854:Vacuolar protein sorting-associated protein 13, N-terminal domain, IPR031645:Vacuolar protein sorting-associated protein 13, C-terminal, IPR031646:Vacuolar protein sorting-associated protein 13, second N-terminal domain" CG15523 11-Aug-17 DroID_v2017_08 "Drer\vps13c, Drer\LOC101882151, Drer\vps13a, Drer\vps13d" Scer\VPS13 "Cele\T08G11.1, Cele\C25H3.11, Cele\C25H3.8" Xtro\vps13b "Mmus\Vps13c, Mmus\Vps13b, Mmus\Vps13a, Mmus\Vps13d" "Hsap\VPS13B, Hsap\VPS13A, Hsap\VPS13D, Hsap\VPS13C" viable FBgn0085510 CG40715 - http://flybase.org/reports/FBgn0085510 protein_coding_gene - - - CG40715 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261587 CG42697 - http://flybase.org/reports/FBgn0261587 protein_coding_gene - - - CG42697 - CG42697 11-Aug-17 DroID_v2017_08 - - - - - - learning defective FBgn0267345 l(4)7-M1365 lethal (4) 7-M1365 http://flybase.org/reports/FBgn0267345 gene - - - l(4)7-M1365 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267199 CR45639 - http://flybase.org/reports/FBgn0267199 non_protein_coding_gene - - - CR45639 - CR45639 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053196 dpy dumpy http://flybase.org/reports/FBgn0053196 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000967 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000967 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000967 chitin-based cuticle attachment to epithelium ; GO:0040005 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR000967 extracellular matrix ; GO:0031012 | inferred from sequence model "dp, Dp, CT35799, CG15637, SP460, DP, olv[D], l(2)24Fd, CR33195, CG31966, CG31968, CG31967, CG33000, CG31725, CG31727, CG33086, CG31965, CG31964, CG31726, CG31724, CG33196, BcDNA:SD02173, Mur24F, DPY, Q8IQ18_DROME, dpy, dumpy" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR006150:Cysteine-rich repeat, IPR001881:EGF-like calcium-binding domain, IPR009030:Growth factor receptor cysteine-rich domain, IPR003645:Follistatin-like, N-terminal, IPR000742:EGF-like domain, IPR001507:Zona pellucida domain, IPR013032:EGF-like, conserved site, IPR024731:EGF domain, IPR000967:Zinc finger, NF-X1-type" CG33196 11-Aug-17 DroID_v2017_08 "Drer\adgrl4, Drer\zgc:158328, Drer\jag1b, Drer\scube1, Drer\col28a1a, Drer\LOC100535882, Drer\col28a1a, Drer\jag1a, Drer\otogl, Drer\ltbp3, Drer\efemp1, Drer\dpy19l1l, Drer\LOC562634, Drer\si:ch73-173h19.3, Drer\crb2b, Drer\sned1, Drer\scospondin, Drer\megf6b, Drer\fbln7, Drer\dlb, Drer\matn3a, Drer\LOC799643, Drer\jag2b, Drer\LOC100332841, Drer\adgrf6, Drer\vwf, Drer\svep1, Drer\jag2a, Drer\scube3, Drer\fbln1, Drer\asic2, Drer\crb2a" "Scer\FLO11, Scer\PRM7, Scer\HKR1, Scer\YMR317W, Scer\MSB2, Scer\HPF1, Scer\FLO1, Scer\FIG2, Scer\FLO5, Scer\FLO9, Scer\YIL169C" "Cele\noah-2, Cele\F32B4.8, Cele\cutl-17, Cele\let-653, Cele\clec-223, Cele\H43E16.1, Cele\fbn-1, Cele\F52C9.5, Cele\T23F1.5, Cele\cutl-27, Cele\H03E18.1, Cele\R07A4.4, Cele\C34C12.7, Cele\ZC449.1, Cele\srap-1, Cele\ZC449.2, Cele\T26C5.2, Cele\H02F09.3, Cele\cutl-18, Cele\ZC178.2, Cele\H42K12.3, Cele\C16D9.1, Cele\noah-1, Cele\dpy-6" "Xtro\svep1, Xtro\matn4, Xtro\notch1, Xtro\ltbp1, Xtro\crb2, Xtro\ltbp4, Xtro\hgfac, Xtro\nell1, Xtro\f12, Xtro\col14a1, Xtro\jag1, Xtro\ltbp3, Xtro\fbn1" "Mmus\Ltbp2, Mmus\Ltbp3, Mmus\Ltbp4, Mmus\Muc2, Mmus\Sned1, Mmus\Dlk1, Mmus\Dlk2, Mmus\Muc4, Mmus\F12, Mmus\Egfl7, Mmus\Col22a1, Mmus\Jag1, Mmus\Muc5ac, Mmus\Tdgf1, Mmus\Vwa1, Mmus\Jag2, Mmus\Fbn1, Mmus\Muc5b, Mmus\Ltbp1, Mmus\Matn3, Mmus\Habp2, Mmus\Scube2, Mmus\Vwde, Mmus\Cfc1, Mmus\Crb2, Mmus\Col28a1, Mmus\Sspo, Mmus\Svep1, Mmus\Fbln7, Mmus\Vwce, Mmus\Scube3, Mmus\Dll3, Mmus\Vwf, Mmus\Hgfac, Mmus\Dll4, Mmus\Muc6, Mmus\Hmcn2" "Hsap\FBN2, Hsap\COL14A1, Hsap\MUC5B, Hsap\SSPO, Hsap\MUC6, Hsap\DLK2, Hsap\COL22A1, Hsap\SCUBE2, Hsap\JAG2, Hsap\HGFAC, Hsap\CFC1B, Hsap\OTOG, Hsap\LOC100996717, Hsap\EGFL7, Hsap\SCUBE3, Hsap\LTBP4, Hsap\TDGF1, Hsap\MUC17, Hsap\CRB2, Hsap\DLK1, Hsap\MUC2, Hsap\LTBP1, Hsap\LTBP3, Hsap\F12, Hsap\SVEP1, Hsap\NOTCH2NL, Hsap\CFC1, Hsap\DLL3, Hsap\DLL4, Hsap\MATN3, Hsap\EYS, Hsap\MUC19, Hsap\SNED1, Hsap\LTBP2, Hsap\MUC4, Hsap\FBLN7, Hsap\MUC16, Hsap\VWA1, Hsap\VWF, Hsap\HABP2, Hsap\JAG1, Hsap\VWCE" "visible,recessive,lethal,enhancer of variegation,dominant,suppressor of variegation,semidominant,immune response defective,somatic clone,cold sensitive,partially lethal - majority die,viable,reduced,wild-type,fertile,planar polarity defective" "adult thorax & adult epidermis,wing,presumptive embryonic/larval tracheal system,adult thorax,thorax,cerebral branch,ventral cephalic branch,pharyngeal branch,dorsal branch,visceral branch,lateral trunk anterior branch,lateral trunk posterior branch,leg,adult abdomen,dorsocentral bristle,mesothoracic tergum,sternopleural bristle,adult,wing blade,somatic clone,endocuticle,thorax & microchaeta,wing vein,macrochaeta,muscle attachment site,chaeta,supernumerary,trichogen cell" FBgn0262448 mir-279 mir-279 stem loop http://flybase.org/reports/FBgn0262448 miRNA_gene - "brain morphogenesis ; GO:0048854 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype gene silencing by RNA ; GO:0031047 | inferred from direct assay wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - "miR-279, mir-279, 279, MIR-279, CR43015, mir-279a, Mir-279, CR33590, dme-mir-279, 0962/07, l(3)S096207, miR279, MiR-279, miR, dme-miR-279, dme-miR-279-3p" - CR43015 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261916 Burdock\env - http://flybase.org/reports/FBgn0261916 transposable_element_gene - - - "Burdock\env, env" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039434 TwdlM TweedleM http://flybase.org/reports/FBgn0039434 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlM, CG5468" IPR004145:Domain of unknown function DUF243 CG5468 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0016662 HeT-A\gag HeT-A element gag http://flybase.org/reports/FBgn0016662 FBgn0013980 transposable_element_gene - - "nuclear chromosome, telomeric region ; GO:0000784 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay chromosome, telomeric region ; GO:0000781 | inferred from direct assay" "ORF, Orf2, Orf1, HeT-A\T, HeT-A\gag, GAG, HeT-A gag, HeT-A Gag, ORF1p, Gag" IPR006579:Pre-C2HC domain - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053242 Ste:CG33242 Ste:CG33242 http://flybase.org/reports/FBgn0053242 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG32605, CG33242, Ste:CG33242" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33242 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0016883 l(2)39DEh lethal (2) 39DEh http://flybase.org/reports/FBgn0016883 - gene - - - "D95, l(2)39DEh" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0061061 l(3)S022242b lethal (3) S022242b http://flybase.org/reports/FBgn0061061 gene - - - "0222/42, l(3)S022242b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0066127 E(sda)G E(sda)G http://flybase.org/reports/FBgn0066127 gene - - - "E(sda)G, Line G" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015936 elg elongatus http://flybase.org/reports/FBgn0015936 - gene - - - elg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060390 l(3)S133804 lethal (3) S133804 http://flybase.org/reports/FBgn0060390 gene - - - "1338/04, l(3)S133804" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011063 l(1)Q16 lethal (1) Q16 http://flybase.org/reports/FBgn0011063 FBgn0010210 gene - - - l(1)Q16 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040629 CG18673 - http://flybase.org/reports/FBgn0040629 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from electronic annotation with InterPro:IPR018338 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR018338 - CG18673 "IPR001148:Alpha carbonic anhydrase, IPR018338:Carbonic anhydrase, alpha-class, conserved site, IPR023561:Carbonic anhydrase, alpha-class" CG18673 11-Aug-17 DroID_v2017_08 "Drer\ca4b, Drer\ca4a, Drer\ca15a, Drer\car15, Drer\ptprga, Drer\ca6, Drer\si:ch211-173d10.4, Drer\ca14, Drer\ca7, Drer\ca4c, Drer\ca10a, Drer\cahz, Drer\ca15b, Drer\ca5a, Drer\ca2, Drer\ca15c, Drer\zgc:153760, Drer\ca16b, Drer\ca8, Drer\ca10b, Drer\ca9, Drer\ca12" - "Cele\cah-6, Cele\cah-5, Cele\cah-3, Cele\cah-4" "Xtro\ca11, Xtro\ca8, Xtro\ca1, Xtro\ca6, Xtro\ca12, Xtro\ca14, Xtro\ca10, Xtro\ca4, Xtro\ca3, Xtro\ca5b, Xtro\LOC779564, Xtro\ca7, Xtro\ca2" "Mmus\Car14, Mmus\Car7, Mmus\Car1, Mmus\Car13, Mmus\Car5b, Mmus\Car11, Mmus\Car12, Mmus\Car10, Mmus\Car6, Mmus\Ptprg, Mmus\Car9, Mmus\Car2, Mmus\Car8, Mmus\Car15, Mmus\Car4, Mmus\Car5a, Mmus\Car3" "Hsap\CA5B, Hsap\CA10, Hsap\CA3, Hsap\CA7, Hsap\CA5A, Hsap\PTPRG, Hsap\CA6, Hsap\CA8, Hsap\CA4, Hsap\CA14, Hsap\CA9, Hsap\CA12, Hsap\CA2, Hsap\CA13, Hsap\CA1, Hsap\CA11" viable FBgn0004215 l(3)84Fc lethal (3) 84Fc http://flybase.org/reports/FBgn0004215 - gene - - - l(3)84Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065744 l(2)SH0520 lethal (2) SH0520 http://flybase.org/reports/FBgn0065744 gene - - - "l(2)SH0520, l(2)SH2 0520" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067735 l(1)G0460 lethal (1) G0460 http://flybase.org/reports/FBgn0067735 gene - - - l(1)G0460 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0260001 TK2 - http://flybase.org/reports/FBgn0260001 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from direct assay TK2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052537 CG32537 - http://flybase.org/reports/FBgn0052537 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG8020, CG32537" - CG32537 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC20073 K 0.475083853 0.638240862 0.134488535 0.052061886 -0.478559526 -1.679502451 FBgn0085642 CG41418 - http://flybase.org/reports/FBgn0085642 protein_coding_gene - - - CG41418 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028953 CG14478 - http://flybase.org/reports/FBgn0028953 protein_coding_gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "CG14478, gene 4, GENE 4, BEST:LD13441" IPR015943:WD40/YVTN repeat-like-containing domain CG14478 11-Aug-17 DroID_v2017_08 "Drer\zgc:194285, Drer\si:ch211-276i12.9, Drer\si:dkey-77f5.3" - Cele\F13B6.1 - - - "behavior defective,recessive,viable" FBgn0260584 2L3267 - http://flybase.org/reports/FBgn0260584 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3267 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0267107 CR45547 - http://flybase.org/reports/FBgn0267107 non_protein_coding_gene - - - CR45547 - CR45547 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005316 Mudd Muddled http://flybase.org/reports/FBgn0005316 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "Muddy, Mudd, Mud" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,viable,male,poor,visible,dominant,eye color defective" "pigment cell,eye" FBgn0042152 CG18829 - http://flybase.org/reports/FBgn0042152 protein_coding_gene - - - CG18829 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053182 Kdm4B Lysine (K)-specific demethylase 4B http://flybase.org/reports/FBgn0053182 protein_coding_gene histone demethylase activity (H3-K9 specific) ; GO:0032454 | inferred from mutant phenotype histone demethylase activity (H3-K36 specific) ; GO:0051864 | inferred from sequence or structural similarity with UniProtKB:O75164 histone demethylase activity (H3-K9 specific) ; GO:0032454 | inferred from direct assay histone demethylase activity (H3-K36 specific) ; GO:0051864 | inferred from mutant phenotype histone demethylase activity (H3-K36 specific) ; GO:0051864 | inferred from direct assay "histone demethylation ; GO:0016577 | inferred from sequence or structural similarity with UniProtKB:O75164 histone H3-K36 demethylation ; GO:0070544 | inferred from mutant phenotype histone H3-K9 demethylation ; GO:0033169 | inferred from direct assay histone H3-K9 demethylation ; GO:0033169 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:O75164" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:O75164 "KDM4B, CG4037, CG33182, Kdm4B, dKDM4B, dJMJD2(2), dKdm4B" "IPR003347:JmjC domain, IPR003349:JmjN domain" CG33182 11-Aug-17 DroID_v2017_08 "Drer\kdm4ab, Drer\kdm4b, Drer\kdm4c, Drer\kdm4aa" "Scer\RPH1, Scer\GIS1" Cele\jmjd-2 "Xtro\kdm4c, Xtro\kdm4a, Xtro\kdm4b" "Mmus\Kdm4a, Mmus\Kdm4b, Mmus\Kdm4d, Mmus\Kdm4c" "Hsap\KDM4E, Hsap\KDM4B, Hsap\KDM4D, Hsap\KDM4C, Hsap\KDM4A" "viable,fertile,radiation sensitive,dominant" embryonic/larval hemocyte | third instar larval stage FBgn0039831 CG12054 - http://flybase.org/reports/FBgn0039831 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000551582" - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000551582 CG12054 IPR013087:Zinc finger C2H2-type CG12054 11-Aug-17 DroID_v2017_08 "Drer\jazf1a, Drer\jazf1b, Drer\LOC572950" Scer\SFP1 Cele\Y67H2A.10 Xtro\jazf1 Mmus\Jazf1 Hsap\JAZF1 DRSC23137 IEK -0.238862644 -2.001025039 0.717613883 3.777608237 -1.687718773 1.232026842 FBgn0034503 MED8 Mediator complex subunit 8 http://flybase.org/reports/FBgn0034503 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR019364 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity regulation of cell cycle ; GO:0051726 | inferred from direct assay transcription from RNA polymerase II promoter ; GO:0006366 | inferred by curator from GO:0001104 mediator complex ; GO:0016592 | inferred from electronic annotation with InterPro:IPR019364 mediator complex ; GO:0016592 | inferred by curator from GO:0001104 mediator complex ; GO:0016592 | inferred from sequence or structural similarity "Arc32, Med8/ARC32, CG13867, dARC32, CG30140, MED8, ARC32, Med8" "IPR019364:Mediator complex, subunit Med8, fungi/metazoa" CG13867 11-Aug-17 DroID_v2017_08 "Drer\med8, Drer\sb:cb829" Scer\MED8 Cele\mdt-8 Xtro\med8 Mmus\Med8 Hsap\MED8 "viable,visible" "chaeta,supernumerary,mesothoracic tergum" DRSC06426 IE -0.290937039 2.253608859 -3.038851375 -0.258714591 0.435619361 0.32275711 FBgn0036380 CG8757 - http://flybase.org/reports/FBgn0036380 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "CG8757, FOHSDR" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG8757 11-Aug-17 DroID_v2017_08 "Drer\zgc:153724, Drer\dhrs11b, Drer\dhrs11a, Drer\zgc:92630" Scer\YMR226C "Cele\F28H7.2, Cele\H04M03.3" Xtro\dhrs11 Mmus\Dhrs11 "Hsap\BDH1, Hsap\DHRS11" viable FBgn0264281 Su(Mir)2A2-1 - http://flybase.org/reports/FBgn0264281 gene - - - Su(Mir)2A2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263844 CR43705 - http://flybase.org/reports/FBgn0263844 non_protein_coding_gene - - - CR43705 - CR43705 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000780 fs(1)A1509 female sterile (1) A1509 http://flybase.org/reports/FBgn0000780 - gene - - - "fs(1)1509, fs(1)A1509" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,non-rescuable maternal effect,recessive,female sterile" gastrula embryo FBgn0265270 CR43239 - http://flybase.org/reports/FBgn0265270 non_protein_coding_gene - - - "lincRNA.170, CR43239, anon-SAGE:Wang-098" - CR43239 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051320 HEATR2 HEAT repeat containing 2 http://flybase.org/reports/FBgn0051320 protein_coding_gene dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN001045098 dynein intermediate chain binding ; GO:0045505 | inferred from sequence or structural similarity with HGNC:26013 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype cilium movement involved in cell motility ; GO:0060294 | inferred from mutant phenotype cilium movement ; GO:0003341 | inferred from biological aspect of ancestor with PANTHER:PTN001045098 inner dynein arm assembly ; GO:0036159 | inferred from mutant phenotype cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:Q86Y56 outer dynein arm assembly ; GO:0036158 | inferred from mutant phenotype flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype motile cilium ; GO:0031514 | NOT inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "NEST:bs27f03, HEATR2, CG31320" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG31320 11-Aug-17 DroID_v2017_08 "Drer\dnaaf5, Drer\dnaaf5" - - Xtro\dnaaf5 Mmus\Dnaaf5 Hsap\DNAAF5 "viable,visible" trichogen cell FBgn0032691 Atac2 Ada2a-containing complex component 2 http://flybase.org/reports/FBgn0032691 protein_coding_gene H4 histone acetyltransferase activity ; GO:0010485 | inferred from direct assay H2A histone acetyltransferase activity ; GO:0043998 | inferred from direct assay positive regulation of histone H4-K16 acetylation ; GO:2000620 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from direct assay histone H2A acetylation ; GO:0043968 | inferred from direct assay histone H4 acetylation ; GO:0043967 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from physical interaction with Ada2a "Atac2, dATAC2, CG10414, KAT14" "IPR000182:GNAT domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR016181:Acyl-CoA N-acyltransferase, IPR019786:Zinc finger, PHD-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10414 11-Aug-17 DroID_v2017_08 Drer\csrp2bp - - Xtro\csrp2bp Mmus\Csrp2bp "Hsap\KAT14, Hsap\PET117" "viable,fertile,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,somatic clone" "intestinal stem cell,somatic clone,supernumerary" FBgn0052267 CG32267 - http://flybase.org/reports/FBgn0052267 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32267 - CG32267 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0065051 scaRNA:MeU5-U42 small Cajal body-specific RNA : MeU5-U42 http://flybase.org/reports/FBgn0065051 snoRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "Dm-755, snoR755, CR33716, MeU5-U42(SnoR755), snoRNA:755, mgU5-42, scaRNA:MeU5-U42, snoRNA:MeU5-U42" - CR33716 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003957 ups upright scutellars http://flybase.org/reports/FBgn0003957 - gene - - - ups - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,reduced,male sterile" "eye,wing,posterior scutellar bristle" FBgn0037021 CG11399 - http://flybase.org/reports/FBgn0037021 protein_coding_gene - "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - CG11399 "IPR001202:WW domain, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR022035:Phosphorylated CTD interacting factor 1, WW domain" CG11399 11-Aug-17 DroID_v2017_08 Drer\pcif1 - - Xtro\pcif1 Mmus\Pcif1 Hsap\PCIF1 "viable,fertile,visible" "wing vein,ectopic,embryonic/larval hemocyte | third instar larval stage,macrochaeta" FBgn0266598 Kmn2 kinetochore Mis12-Ndc80 network component 2 http://flybase.org/reports/FBgn0266598 protein_coding_gene - - Ndc80 complex ; GO:0031262 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay "HDC12388, Kmn2, CG42550" - CG42550 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250836 CG8628 - http://flybase.org/reports/FBgn0250836 protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 - - "CG8628, anon-SAGE:Wang-073" "IPR000582:Acyl-CoA-binding protein, ACBP, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR022408:Acyl-CoA-binding protein, ACBP, conserved site" CG8628 11-Aug-17 DroID_v2017_08 "Drer\mettl23, Drer\acbd6, Drer\zgc:92030, Drer\acbd5b, Drer\LOC103909942, Drer\dbi, Drer\acbd7, Drer\acbd4" Scer\ACB1 "Cele\acbp-1, Cele\acbp-5, Cele\acbp-6, Cele\acbp-4, Cele\acbp-3, Cele\maa-1" "Xtro\acbd5, Xtro\eci2, Xtro\acbd7, Xtro\acbd6, Xtro\mettl23" "Mmus\Acbd5, Mmus\Eci2, Mmus\Mettl23, Mmus\Dbi, Mmus\Acbd7, Mmus\Dbil5, Mmus\Acbd6, Mmus\Acbd4" "Hsap\ACBD5, Hsap\ACBD6, Hsap\ACBD4, Hsap\ACBD7, Hsap\DBI, Hsap\ECI2, Hsap\METTL23" FBgn0266206 CR44901 - http://flybase.org/reports/FBgn0266206 non_protein_coding_gene - - - CR44901 - CR44901 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085488 CG34459 - http://flybase.org/reports/FBgn0085488 protein_coding_gene molecular_function ; GO:0003674 | no biological data available developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 cellular_component ; GO:0005575 | no biological data available "CG34459, CG6301" IPR007999:Protein of unknown function DUF745 CG34459 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037162 CG11449 - http://flybase.org/reports/FBgn0037162 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11449 IPR033253:Cilia- and flagella-associated protein 45 CG11449 11-Aug-17 DroID_v2017_08 Drer\cfap45 - Cele\K09F6.9 Xtro\cfap45 Mmus\Cfap45 Hsap\CFAP45 viable DRSC11662 E 0.317413761 1.135001344 -1.551967676 0.94914908 0.45962852 0.739851471 FBgn0031248 CG11912 - http://flybase.org/reports/FBgn0031248 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP140, anon-WO0140519.112, CG11912" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11912 11-Aug-17 DroID_v2017_08 "Drer\zgc:112160, Drer\si:dkey-238d18.3, Drer\ctrb1, Drer\ctrl, Drer\LOC562139, Drer\zgc:171592" - - - "Mmus\Prss38, Mmus\Ctrl, Mmus\Ctrb1, Mmus\Prtn3" "Hsap\CTRL, Hsap\CTRB2, Hsap\PRTN3, Hsap\PRSS38, Hsap\AZU1, Hsap\CTRB1" viable FBgn0065543 l(2)SH1056 lethal (2) SH1056 http://flybase.org/reports/FBgn0065543 gene - - - "l(2)SH1056, l(2)SH2 1056" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0054050 CG34050 - http://flybase.org/reports/FBgn0054050 protein_coding_gene - - - "BP1085, HDC09511, CG34050, mdcds_24470" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC09067 IK -0.596218742 -2.4328824 -0.25498206 -1.423359296 0.963259994 2.818725041 FBgn0017389 l(1)15Db lethal (1) 15Db http://flybase.org/reports/FBgn0017389 - gene - - - l(1)15Db - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024716 anon-26Ab anon-26Ab http://flybase.org/reports/FBgn0024716 - gene - - - anon-26Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031085 CG9570 - http://flybase.org/reports/FBgn0031085 protein_coding_gene - - - CG9570 IPR032145:Protein of unknown function DUF4818 CG9570 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0067779 dbr debra http://flybase.org/reports/FBgn0067779 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 long-term memory ; GO:0007616 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 multivesicular body ; GO:0005771 | inferred from direct assay "dbr, CG11371, Dbr, EP456, BcDNA:LD26519, EP0456, Debra" "IPR012934:Zinc finger, AD-type" CG11371 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,RU486 conditional,visible,lethal,viable" "wing vein L3,somatic clone,wing vein L4,ectopic,crossvein,macrochaeta,tormogen cell,trichogen cell,eye,external sensory organ,micropyle,drug conditional,dorsal appendage" FBgn0250819 CG33521 - http://flybase.org/reports/FBgn0250819 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 - - "CG17467, anon2D9, 2D9, anon-EST:fe2E7, anon-EST:fe2D9, anon-EST:fe2A9, CG32015, CG33521, BcDNA:RE73965" "IPR001781:Zinc finger, LIM-type" CG33521 11-Aug-17 DroID_v2017_08 "Drer\csrp1b, Drer\csrp1a, Drer\csrp3, Drer\nrap, Drer\csrp2" Scer\LRG1 "Cele\tag-273, Cele\mlp-1" Xtro\lima1 "Mmus\Csrp2, Mmus\Csrp1, Mmus\Csrp3, Mmus\Nrap, Mmus\Limd2, Mmus\Lima1" "Hsap\CSRP3, Hsap\LIMA1, Hsap\CSRP1, Hsap\NRAP, Hsap\LIMD2, Hsap\CSRP2" FBgn0036939 CG7365 - http://flybase.org/reports/FBgn0036939 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR001087" phagocytosis ; GO:0006909 | inferred from mutant phenotype - CG7365 "IPR001087:GDSL lipase/esterase, IPR013830:SGNH hydrolase-type esterase domain" CG7365 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-177p2.18, Drer\si:ch211-214p16.3" - "Cele\T19D7.7, Cele\F09C8.1, Cele\Y40B10A.9, Cele\F36A2.9, Cele\W02B12.1, Cele\F13H8.11, Cele\R07B7.9, Cele\Y73B6BL.37, Cele\R07B7.8, Cele\Y65B4BR.1" "Xtro\plb1, Xtro\LOC101732808" Mmus\Plb1 Hsap\PLB1 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0267601 CR45939 - http://flybase.org/reports/FBgn0267601 non_protein_coding_gene - - - CR45939 - CR45939 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013609 l(3)E7-3-58 lethal (3) E7-3-58 http://flybase.org/reports/FBgn0013609 - gene - - - l(3)E7-3-58 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0041599 l(2)IIa lethal (2) IIa http://flybase.org/reports/FBgn0041599 gene - - - l(2)IIa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032311 CG12517 - http://flybase.org/reports/FBgn0032311 protein_coding_gene cytokine activity ; GO:0005125 | inferred from sequence or structural similarity with Gbp1 signal transduction ; GO:0007165 | inferred from sequence or structural similarity with Gbp1 chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern chorion ; GO:0042600 | inferred by curator from GO:0007304 CG12517 - CG12517 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032966 CG1421 - http://flybase.org/reports/FBgn0032966 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:LP11549, CG1421" "IPR007846:RNA-recognition motif (RRM) Nup35-type domain, IPR000504:RNA recognition motif domain" CG1421 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029514 312 312 http://flybase.org/reports/FBgn0029514 protein_coding_gene ribosomal large subunit binding ; GO:0043023 | inferred from biological aspect of ancestor with PANTHER:PTN000471516 negative regulation of translation ; GO:0017148 | inferred from biological aspect of ancestor with PANTHER:PTN000471516 negative regulation of ribosome biogenesis ; GO:0090071 | inferred from biological aspect of ancestor with PANTHER:PTN000471516 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000471518 "BEST:CK01660, CG9166, 312" IPR004394:Protein Iojap/ribosomal silencing factor RsfS CG9166 11-Aug-17 DroID_v2017_08 Drer\si:zfos-1192g2.3 - Cele\K12H4.2 Xtro\malsu1 Mmus\Malsu1 Hsap\MALSU1 viable FBgn0058121 CG40121 - http://flybase.org/reports/FBgn0058121 protein_coding_gene - - - CG40121 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065427 l(2)SH1513 lethal (2) SH1513 http://flybase.org/reports/FBgn0065427 gene - - - l(2)SH1513 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034126 jtb jetboil http://flybase.org/reports/FBgn0034126 protein_coding_gene - detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype - "CG4398, jtb" IPR010629:Insect allergen-related CG4398 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0041614 TAS Telomeric Associated Sequences http://flybase.org/reports/FBgn0041614 repeat_region - - - TAS - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038564 CG7785 - http://flybase.org/reports/FBgn0038564 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7785, CLLD6" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR003877:SPRY domain" CG7785 11-Aug-17 DroID_v2017_08 "Drer\spryd7a, Drer\spryd7b" - Cele\F18H3.1 Xtro\spryd7 Mmus\Spryd7 Hsap\SPRYD7 "viable,fertile" FBgn0001716 l(1)ESHS37 lethal (1) ESHS37 http://flybase.org/reports/FBgn0001716 - gene - - - l(1)ESHS37 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262144 CG42870 - http://flybase.org/reports/FBgn0262144 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42870, lincRNA.828" - CG42870 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263336 CR43417 - http://flybase.org/reports/FBgn0263336 non_protein_coding_gene - - - CR43417 - CR43417 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000916 fs(1)ne2 female sterile (1) no eggs 2 http://flybase.org/reports/FBgn0000916 - gene - - - "ne2, fs(1)ne[2], fs(1)ne2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "dorsal appendage,chorion,endochorion,oocyte" FBgn0028651 anon-55Ea anon-55Ea http://flybase.org/reports/FBgn0028651 gene - - - "A-2300, anon-55Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017387 l(1)15Dd lethal (1) 15Dd http://flybase.org/reports/FBgn0017387 - gene - - - l(1)15Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000372 cripA crippled A http://flybase.org/reports/FBgn0000372 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "crpA, cripA" - - 11-Aug-17 DroID_v2017_08 - - - - - - "hypoactive,uncoordinated" FBgn0035070 CG3650 - http://flybase.org/reports/FBgn0035070 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP159, CG3650" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG3650 11-Aug-17 DroID_v2017_08 - - "Cele\try-1, Cele\try-5, Cele\svh-1" - Mmus\Gzmk - pupal stage salivary gland

viable FBgn0082936 snoRNA:Me28S-C2645c - http://flybase.org/reports/FBgn0082936 snoRNA_gene - - - "CR34589, snoRNA:Me28S-C2645c, Me28S-Cm2645c, snoRNA:Me28S-Cm2645c, DmSnR64c" - CR34589 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052728 CR32728 - http://flybase.org/reports/FBgn0052728 non_protein_coding_gene - - - CR32728 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019847 anon-XVIII anon-XVIII http://flybase.org/reports/FBgn0019847 - gene - - - "XVIII, anon-XVIII" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013594 l(3)A519.1F3 lethal (3) A519.1F3 http://flybase.org/reports/FBgn0013594 - gene - - - l(3)A519.1F3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069244 daltonian daltonian http://flybase.org/reports/FBgn0069244 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available daltonian - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086021 snoRNA:MeU6-C68 - http://flybase.org/reports/FBgn0086021 snoRNA_gene - - - "snoRNA:MeU6-C68, MeU6-Cm68, MeU6-C68, CR34650, mgU6-68" - CR34650 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069079 stoc stocherkahn http://flybase.org/reports/FBgn0069079 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available stoc - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal,germline clone,non-rescuable maternal effect" "dorsal closure embryo,germline clone,non-rescuable maternal effect,maternal effect" FBgn0019985 mGluR metabotropic Glutamate Receptor http://flybase.org/reports/FBgn0019985 - protein_coding_gene group II metabotropic glutamate receptor activity ; GO:0001641 | inferred from direct assay glutamate binding ; GO:0016595 | inferred from direct assay G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity glutamate receptor activity ; GO:0008066 | inferred from sequence or structural similarity cholesterol binding ; GO:0015485 | inferred from direct assay "long-term memory ; GO:0007616 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype learning ; GO:0007612 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype regulation of synaptic transmission, glutamatergic ; GO:0051966 | inferred from mutant phenotype G-protein coupled glutamate receptor signaling pathway ; GO:0007216 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from mutant phenotype G-protein coupled glutamate receptor signaling pathway ; GO:0007216 | inferred from sequence or structural similarity" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity G-protein coupled receptor homodimeric complex ; GO:0038038 | inferred from sequence or structural similarity with HGNC:4593 integral component of plasma membrane ; GO:0005887 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay membrane raft ; GO:0045121 | inferred from direct assay "CAA67993.1_Dr, DmGluAR, DmGluRA, DmGlu-A, DmGluR[[A]], DmGluR, dmGluRA, CG11144, mGluR, DmGlu-RA, Glu-RA, DmGlu[[A]]R, DmGluA, GluR, mGLuR, mGluRA" "IPR017978:GPCR family 3, C-terminal, IPR017979:GPCR, family 3, conserved site, IPR000162:GPCR, family 3, metabotropic glutamate receptor, IPR000337:GPCR, family 3, IPR001828:Receptor, ligand binding region, IPR011500:GPCR, family 3, nine cysteines domain, IPR028082:Periplasmic binding protein-like I" CG11144 11-Aug-17 DroID_v2017_08 "Drer\grm1b, Drer\grm5b, Drer\grm5a, Drer\grm6a, Drer\si:ch1073-155h21.1, Drer\grm8a, Drer\grm2b, Drer\grm6b, Drer\grm3, Drer\grm4, Drer\gprc5c, Drer\tas1r3, Drer\tas1r2.1, Drer\gprc5bb, Drer\grm1a, Drer\grm8b, Drer\tas1r2.2, Drer\grm2a" - "Cele\mgl-3, Cele\mgl-2, Cele\mgl-1" "Xtro\gprc5a, Xtro\grm5, Xtro\gprc5c, Xtro\gprc5c, Xtro\grm3, Xtro\grm4, Xtro\grm7, Xtro\grm1" "Mmus\Vmn2r20, Mmus\Vmn2r102, Mmus\Vmn2r106, Mmus\Vmn2r90, Mmus\Vmn2r108, Mmus\Vmn2r94, Mmus\Vmn2r110, Mmus\Gprc5b, Mmus\Vmn2r109, Mmus\Grm3, Mmus\Vmn2r58, Mmus\Vmn2r92, Mmus\Grm1, Mmus\Grm7, Mmus\Vmn2r100, Mmus\Vmn2r104, Mmus\Grm5, Mmus\Vmn2r21, Mmus\Tas1r1, Mmus\Grm4, Mmus\Vmn2r59, Mmus\Tas1r3, Mmus\Vmn2r60, Mmus\Vmn2r56, Mmus\Vmn2r97, Mmus\Vmn2r105, Mmus\Grm2, Mmus\Vmn2r22, Mmus\Grm6, Mmus\Grm8, Mmus\Gprc5d, Mmus\Vmn2r61, Mmus\Vmn2r98, Mmus\Gprc5a" "Hsap\GRM2, Hsap\GRM3, Hsap\GPRC5C, Hsap\GPRC5D, Hsap\TAS1R3, Hsap\GPRC5B, Hsap\GRM4, Hsap\GRM5, Hsap\GRM7, Hsap\GPRC5A, Hsap\GRM1, Hsap\GRM6, Hsap\TAS1R1, Hsap\GRM8" "viable,neurophysiology defective,neuroanatomy defective,recessive" "type I bouton,bouton,supernumerary" FBgn0039483 CG14259 - http://flybase.org/reports/FBgn0039483 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG14259 IPR010562:Haemolymph juvenile hormone binding CG14259 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265704 CR44511 - http://flybase.org/reports/FBgn0265704 non_protein_coding_gene - - - "lincRNA.396, CR44511" - CR44511 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265102 Oseg1 Outer segment 1 http://flybase.org/reports/FBgn0265102 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein localization to cilium ; GO:0061512 | inferred from biological aspect of ancestor with PANTHER:PTN000298746 intraciliary retrograde transport ; GO:0035721 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern intraciliary transport particle A ; GO:0030991 | inferred from sequence or structural similarity with HGNC:13556 non-motile cilium ; GO:0097730 | inferred from direct assay intraciliary transport particle A ; GO:0030991 | inferred from biological aspect of ancestor with PANTHER:PTN000298746 "Oseg1, IFT122, mecC, DAF-10, OSEG1, CG7161, oseg1, OSEG, OSM-4, Wdr10" "IPR011990:Tetratricopeptide-like helical domain, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat" CG7161 11-Aug-17 DroID_v2017_08 Drer\ift122 - Cele\daf-10 Xtro\ift122 "Mmus\Wdr19, Mmus\Ift122" "Hsap\IFT122, Hsap\IFT172" FBgn0065416 l(2)SH1541 lethal (2) SH1541 http://flybase.org/reports/FBgn0065416 gene - - - "l(2)SH1541, l(2)SH2 1541" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266203 CR44898 - http://flybase.org/reports/FBgn0266203 non_protein_coding_gene - - - CR44898 - CR44898 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035016 CG4612 - http://flybase.org/reports/FBgn0035016 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity poly(A) binding ; GO:0008143 | inferred from sequence or structural similarity with SGD:S000000967 positive regulation of translation ; GO:0045727 | inferred from direct assay long-term memory ; GO:0007616 | inferred from mutant phenotype - "cg4612, CG4612" IPR000504:RNA recognition motif domain CG4612 11-Aug-17 DroID_v2017_08 "Drer\eif4h, Drer\srsf10a, Drer\cirbpa, Drer\hnrnpaba, Drer\trnau1apb, Drer\trnau1apa, Drer\ncoa5, Drer\zgc:55733, Drer\rbm34, Drer\pabpc1b, Drer\zcrb1, Drer\hnrpdl, Drer\hnrnpa3, Drer\wu:fq32h04, Drer\hnrnpabb, Drer\pabpc1a, Drer\hnrnpd, Drer\hnrnpc, Drer\pabpc1l, Drer\dazl, Drer\hnrnpa1b, Drer\raly, Drer\pabpc4, Drer\eif4ba" "Scer\NGR1, Scer\PRP24, Scer\NOP12, Scer\NOP6, Scer\RIM4, Scer\MUD1, Scer\NSR1, Scer\NAB6, Scer\NAM8, Scer\CWC2, Scer\MRN1, Scer\PAB1" "Cele\K07H8.10, Cele\pab-1, Cele\sart-3, Cele\pab-2, Cele\R05D3.8" "Xtro\dazl, Xtro\hnrnpdl, Xtro\ralyl, Xtro\trnau1ap, Xtro\hnrnpa2b1, Xtro\cirbp, Xtro\pabpc4, Xtro\hnrnpab, Xtro\hnrnpa1, Xtro\pabpc1, Xtro\hnrnpd, Xtro\hnrnpc, Xtro\eif4h, Xtro\pabpc1l, Xtro\raly, Xtro\hnrnpa3, Xtro\eif4b, Xtro\rbm34" "Mmus\Gm21379, Mmus\Trnau1ap, Mmus\Boll, Mmus\Pabpc2, Mmus\Pabpc1, Mmus\Srsf10, Mmus\Hnrnpc, Mmus\Hnrnpa1, Mmus\Rbm34, Mmus\Slirp, Mmus\Hnrnpdl, Mmus\Srsf12, Mmus\Dazl, Mmus\Pabpc1l, Mmus\Cirbp, Mmus\Sart3, Mmus\Pabpc4, Mmus\Hnrnpa3, Mmus\Eif4h, Mmus\Pabpc6, Mmus\Raly, Mmus\Eif4b, Mmus\Rbm31y, Mmus\Hnrnpd, Mmus\Hnrnpab, Mmus\Hnrnpa2b1, Mmus\Tra2b, Mmus\Pabpc5, Mmus\Zcrb1, Mmus\Pabpc4l" "Hsap\DAZ4, Hsap\PABPC1L2A, Hsap\PABPC4L, Hsap\HNRNPA3, Hsap\HNRNPAB, Hsap\PABPC1, Hsap\PABPC1L, Hsap\RBM3, Hsap\DAZ1, Hsap\BOLL, Hsap\EIF4B, Hsap\PABPC5, Hsap\HNRNPA2B1, Hsap\HNRNPC, Hsap\SRSF10, Hsap\RALY, Hsap\HNRNPA1, Hsap\EIF4H, Hsap\CIRBP, Hsap\DAZL, Hsap\HNRNPCL1, Hsap\DAZ2, Hsap\PABPC4, Hsap\SART3, Hsap\RALYL, Hsap\RBM34, Hsap\HNRNPD, Hsap\PABPC1L2B, Hsap\HNRNPA1L2, Hsap\TRNAU1AP, Hsap\DAZ3, Hsap\SLIRP, Hsap\HNRNPDL, Hsap\PABPC3" visible wing FBgn0005146 l(2)DTS9 lethal (2) DTS9 http://flybase.org/reports/FBgn0005146 - gene - - - "DTS-L9, l(2)DTS9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,recessive" FBgn0020844 l(2)21Ba1 lethal (2) 21Ba1 http://flybase.org/reports/FBgn0020844 - gene - - - "21Ba1, l(2)21Ba1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065940 l(2)SH0116 lethal (2) SH0116 http://flybase.org/reports/FBgn0065940 gene - - - l(2)SH0116 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083075 ms(3)236 ms(3)236 http://flybase.org/reports/FBgn0083075 gene - - - ms(3)236 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042147 CG18824 - http://flybase.org/reports/FBgn0042147 protein_coding_gene - - - CG18824 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027609 morgue "modifier of rpr and grim, ubiquitously expressed" http://flybase.org/reports/FBgn0027609 - protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model K48-linked polyubiquitin binding ; GO:0036435 | inferred from direct assay regulation of retinal cell programmed cell death ; GO:0046668 | non-traceable author statement SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype positive regulation of compound eye retinal cell apoptotic process ; GO:1901694 | inferred from mutant phenotype inferred from genetic interaction with Diap1 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | non-traceable author statement "CG15437, BcDNA:GH02435, morgue, Morgue, FBXO18" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR001810:F-box domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG15437 11-Aug-17 DroID_v2017_08 "Drer\ube2e2, Drer\ube2d3, Drer\ube2t, Drer\ube2d4, Drer\ube2d2, Drer\ube2na, Drer\ube2d2l, Drer\ube2d1a, Drer\ube2e3, Drer\ube2e1, Drer\ube2d1b, Drer\ube2nb" "Scer\UBC13, Scer\UBC5, Scer\UBC4, Scer\PEX4" "Cele\let-70, Cele\uev-2" "Xtro\ube2d4, Xtro\ube2e3, Xtro\ube2e2, Xtro\ube2d1, Xtro\ube2d3, Xtro\ube2e1, Xtro\ube2n" "Mmus\Ube2e1, Mmus\Ube2dnl2, Mmus\Ube2d3, Mmus\Ube2d2b, Mmus\Ube2t, Mmus\Ube2dnl1, Mmus\Ube2n, Mmus\Ube2d1, Mmus\Ube2d2a, Mmus\Ube2e3, Mmus\Ube2e2" "Hsap\UBE2NL, Hsap\UBE2E1, Hsap\UBE2N, Hsap\UBE2D3, Hsap\UBE2T, Hsap\UBE2E3, Hsap\UBE2D2, Hsap\UBE2D1, Hsap\UBE2E2, Hsap\UBE2D4" " embryonic stage -- adult stage , pupal stage--adult stage , pupal stage " " organism

, primary pigment cell

, tertiary pigment cell

, secondary pigment cell

" "viable,hypoactive,visible,decreased cell death,recessive,partially lethal - majority die,melanotic mass phenotype,lethal,some die during third instar larval stage,some die during pupal stage,partially lethal" "anterior pupal spiracle,tergite,midline glial cell,supernumerary,pigment cell,chaeta,leg,melanotic mass,embryonic peripheral glial cell 10,support cell of the dorsal bipolar dendritic cell" DRSC00264 I 0.578050001 -1.543783132 0.284723587 0.115384271 -0.532947828 -0.51377844 FBgn0046709 GIIIC GIIIC http://flybase.org/reports/FBgn0046709 gene phospholipase A2 activity ; GO:0004623 | non-traceable author statement - extracellular region ; GO:0005576 | non-traceable author statement "dGIIIC, GIIIC" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023507 D2hgdh D-2-hydroxyglutaric acid dehydrogenase http://flybase.org/reports/FBgn0023507 - protein_coding_gene FAD binding ; GO:0071949 | inferred from biological aspect of ancestor with PANTHER:PTN001714811 (R)-2-hydroxyglutarate dehydrogenase activity ; GO:0051990 | inferred from mutant phenotype D-lactate dehydrogenase (cytochrome) activity ; GO:0004458 | inferred from biological aspect of ancestor with PANTHER:PTN001714811 lactate oxidation ; GO:0019516 | inferred from biological aspect of ancestor with PANTHER:PTN001714811 respiratory electron transport chain ; GO:0022904 | inferred from biological aspect of ancestor with PANTHER:PTN001714811 oxidation-reduction process ; GO:0055114 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000202300 "EG87B1, EG:87B1.3, CG3835, D2hgdh, D2HGDH" "IPR004113:FAD-linked oxidase, C-terminal, IPR006094:FAD linked oxidase, N-terminal, IPR016164:FAD-linked oxidase-like, C-terminal, IPR016166:FAD-binding, type 2, IPR016167:FAD-binding, type 2, subdomain 1, IPR016169:CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR016171:Vanillyl-alcohol oxidase, C-terminal subdomain 2" CG3835 11-Aug-17 DroID_v2017_08 Drer\d2hgdh "Scer\DLD1, Scer\DLD3, Scer\DLD2" Cele\F54D5.12 Xtro\d2hgdh "Mmus\Ldhd, Mmus\D2hgdh" "Hsap\D2HGDH, Hsap\LDHD" "partially lethal - majority die,some die during pupal stage" FBgn0065710 l(2)SH0598 lethal (2) SH0598 http://flybase.org/reports/FBgn0065710 gene - - - "l(2)SH0598, l(2)SH2 0598" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035791 CG8539 - http://flybase.org/reports/FBgn0035791 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG8539 "IPR000834:Peptidase M14, carboxypeptidase A, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain" CG8539 11-Aug-17 DroID_v2017_08 "Drer\cpo, Drer\cpa4, Drer\cpa6, Drer\cpb2, Drer\cpa2, Drer\cpa5, Drer\cpb1, Drer\cpa1" Scer\ECM14 "Cele\suro-1, Cele\W01A8.6, Cele\T06A4.3, Cele\Y47G6A.19, Cele\T06A4.1, Cele\F02D8.4, Cele\Y18H1A.9, Cele\Y59C2A.1, Cele\ZC434.9" "Xtro\cpo, Xtro\cpa1, Xtro\cpb2, Xtro\cpb1, Xtro\cpa3" "Mmus\Cpa3, Mmus\Cpa1, Mmus\Cpa5, Mmus\Cpa2, Mmus\Cpa6, Mmus\Cpb1, Mmus\Cpb2, Mmus\Cpa4" "Hsap\CPA6, Hsap\CPO, Hsap\CPA5, Hsap\CPB1, Hsap\CPA1, Hsap\CPA2, Hsap\CPA4, Hsap\CPA3, Hsap\CPB2" FBgn0061482 rover\pol rover element pol http://flybase.org/reports/FBgn0061482 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - rover\pol "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069086 sah sahnehaeubchen http://flybase.org/reports/FBgn0069086 gene molecular_function ; GO:0003674 | no biological data available oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sah - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" chorion | germline clone | maternal effect FBgn0001057 Fs(3)Kev Female sterile (3) Keve http://flybase.org/reports/FBgn0001057 - gene - - - "Fs(3)Keve, Fs(3)Sz16, Fs(3)Kev" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0266943 CR45394 - http://flybase.org/reports/FBgn0266943 non_protein_coding_gene - - - CR45394 - CR45394 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260770 CG42568 - http://flybase.org/reports/FBgn0260770 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42568, CG13571, CG12240" - CG42568 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062696 EP1191 EP1191 http://flybase.org/reports/FBgn0062696 gene - - - "EP(3)1191, EP1191" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031857 LUBEL Linear Ubiquitin E3 ligase http://flybase.org/reports/FBgn0031857 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001876 K63-linked polyubiquitin binding ; GO:0070530 | inferred from direct assay K48-linked polyubiquitin binding ; GO:0036435 | inferred from direct assay ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:16031 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay linear polyubiquitin binding ; GO:1990450 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model" protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:16031 protein linear polyubiquitination ; GO:0097039 | inferred from direct assay heat acclimation ; GO:0010286 | inferred from mutant phenotype LUBAC complex ; GO:0071797 | inferred from electronic annotation with InterPro:IPR026254 cellular_component ; GO:0005575 | no biological data available "AAF52435.2, LUBEL, CG11321" "IPR001876:Zinc finger, RanBP2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR026254:E3 ubiquitin-protein ligase RNF31, IPR001841:Zinc finger, RING-type, IPR002867:IBR domain, IPR032065:E3 ubiquitin-protein ligase RNF31, UB-associated-like domain" CG11321 11-Aug-17 DroID_v2017_08 "Drer\LOC100334178, Drer\si:dkey-181m9.8, Drer\rnf216" - - "Xtro\rnf31, Xtro\rnf216" "Mmus\Rnf216, Mmus\Rnf31" "Hsap\RNF31, Hsap\RNF216" viable FBgn0266707 CR45197 - http://flybase.org/reports/FBgn0266707 non_protein_coding_gene - - - CR45197 - CR45197 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266213 CR44908 - http://flybase.org/reports/FBgn0266213 non_protein_coding_gene - - - CR44908 - CR44908 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085495 CG40534 - http://flybase.org/reports/FBgn0085495 protein_coding_gene - - - CG40534 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004772 l(3)91Ca lethal (3) 91Ca http://flybase.org/reports/FBgn0004772 - gene - - - "l(3)CR1, l(3)91Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030088 Arfrp1 ADP-ribosylation factor related protein 1 http://flybase.org/reports/FBgn0030088 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006689, InterPro:IPR024156" small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 biological_process ; GO:0008150 | no biological data available intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR024156 cellular_component ; GO:0005575 | no biological data available "CG7039, Q9W389, Arp1, Arfrp1, ARFRP1, ARP" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024156:Small GTPase superfamily, ARF type" CG7039 11-Aug-17 DroID_v2017_08 "Drer\arfrp1, Drer\arl13b" Scer\ARL3 Cele\Y54E10BR.2 "Xtro\eral1, Xtro\arfrp1" "Mmus\Arl13b, Mmus\Arfrp1" "Hsap\ARL13B, Hsap\ARFRP1" "lethal,viable,visible" "embryonic/larval brain,trichogen cell" DRSC18417 K -0.099003464 -0.10536053 -0.472733818 -1.35336419 0.352440365 1.628296447 FBgn0265745 CR44552 - http://flybase.org/reports/FBgn0265745 non_protein_coding_gene - - - CR44552 - CR44552 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024862 l(3)09402 lethal (3) 09402 http://flybase.org/reports/FBgn0024862 - gene - - - "9402, l(3)09402" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051308 CG31308 - http://flybase.org/reports/FBgn0051308 protein_coding_gene - - - CG31308 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025839 ND-B14.5A NADH dehydrogenase (ubiquinone) B14.5 A subunit http://flybase.org/reports/FBgn0025839 "FBgn0014087, FBgn0047059" protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR009947 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95182 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from biological aspect of ancestor with PANTHER:PTN000968153 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95182" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000968153 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95182 "anon-2Db, 152A3.7, EG:152A3.7, RNAA, anon-2D, BcDNA:RE75088, CG3621, N4AM, ND-B14.5A" IPR009947:NADH:ubiquinone oxidoreductase subunit B14.5a CG3621 11-Aug-17 DroID_v2017_08 Drer\ndufa7 - Cele\F45H10.3 - Mmus\Ndufa7 Hsap\NDUFA7 FBgn0035077 CG9083 - http://flybase.org/reports/FBgn0035077 protein_coding_gene - - - CG9083 - CG9083 11-Aug-17 DroID_v2017_08 - Scer\RNQ1 - - - - FBgn0040247 anon-57Ba anon-57Ba http://flybase.org/reports/FBgn0040247 gene - - - anon-57Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263443 CR43466 - http://flybase.org/reports/FBgn0263443 non_protein_coding_gene - - - CR43466 - CR43466 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267046 CG45490 - http://flybase.org/reports/FBgn0267046 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45490 - CG45490 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001527 l(1)11Ec lethal (1) 11Ec http://flybase.org/reports/FBgn0001527 - gene - - - l(1)11Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0050274 CG30274 - http://flybase.org/reports/FBgn0050274 protein_coding_gene "kinase activity ; GO:0016301 | inferred from electronic annotation with InterPro:IPR022413, InterPro:IPR022414" - - "CG13529, CG30274" "IPR000749:ATP:guanido phosphotransferase, IPR014746:Glutamine synthetase/guanido kinase, catalytic domain, IPR022413:ATP:guanido phosphotransferase, N-terminal, IPR022414:ATP:guanido phosphotransferase, catalytic domain" CG30274 11-Aug-17 DroID_v2017_08 "Drer\ckbb, Drer\ckmt2b, Drer\ckma, Drer\ckmb, Drer\ckba, Drer\zgc:172076, Drer\ckmt1, Drer\ckmt2a" - "Cele\ZC434.8, Cele\F32B5.1, Cele\F11G11.13, Cele\F46H5.3, Cele\argk-1, Cele\W10C8.5" "Xtro\ckb, Xtro\ckm, Xtro\ckmt1b" "Mmus\Ckmt2, Mmus\Ckmt1, Mmus\Ckm, Mmus\Ckb" "Hsap\CKM, Hsap\CKMT1A, Hsap\CKMT1B, Hsap\CKMT2, Hsap\CKB" viable FBgn0010123 l(1)EN7 lethal (1) from Eugene Nonautonomous 7 http://flybase.org/reports/FBgn0010123 - gene - - - l(1)EN7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" fat body FBgn0015913 big bendless interacting gene product http://flybase.org/reports/FBgn0015913 - gene - - - big - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028844 CG15283 - http://flybase.org/reports/FBgn0028844 protein_coding_gene - regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype - "DS08340.1, BG:DS08340.1, CG15283" IPR012875:Protein of unknown function DUF1674 CG15283 11-Aug-17 DroID_v2017_08 Drer\sdhaf4 Scer\SDH8 Cele\W02D3.12 Xtro\sdhaf4 Mmus\Sdhaf4 Hsap\SDHAF4 "viable,planar polarity defective" "wing hair,ommatidium" FBgn0039101 CG16710 - http://flybase.org/reports/FBgn0039101 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG16710, SP16" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG16710 11-Aug-17 DroID_v2017_08 "Drer\f9a, Drer\masp2, Drer\f10" - "Cele\svh-1, Cele\try-1" Xtro\f2 "Mmus\Klk1b9, Mmus\F10, Mmus\Klk1b5, Mmus\F9" "Hsap\F2, Hsap\MASP1" "viable,visible" trichogen cell FBgn0040322 GNBP2 Gram-negative bacteria binding protein 2 http://flybase.org/reports/FBgn0040322 protein_coding_gene (1->3)-beta-D-glucan binding ; GO:0001872 | inferred from direct assay lipopolysaccharide binding ; GO:0001530 | inferred from direct assay signaling pattern recognition receptor activity ; GO:0008329 | inferred from sequence or structural similarity with GNBP1 beta-glucanase activity ; GO:0052736 | NOT inferred from key residues carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000757 regulation of innate immune response ; GO:0045088 | inferred from sequence or structural similarity with UniProtKB:Q9NHB0 innate immune response-activating signal transduction ; GO:0002758 | inferred from sequence or structural similarity with GNBP1 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:Q9NHB0 proteasome complex ; GO:0000502 | colocalizes_with inferred from direct assay "GNBP, DGNBP-2, CG4144, GNBP2, gnbp2" "IPR000757:Glycoside hydrolase family 16, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR031756:Beta-1,3-glucan-binding protein, N-terminal" CG4144 11-Aug-17 DroID_v2017_08 - "Scer\CRR1, Scer\UTR2, Scer\CRH1" Cele\Y53H1B.4 - - - viable FBgn0063904 Neurodegeneration-7 Neurodegeneration 7 http://flybase.org/reports/FBgn0063904 gene - - - "ND8, ND7, Neurodegeneration-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,dominant" "central nervous system,brain" FBgn0053245 Ste:CG33245 Ste:CG33245 http://flybase.org/reports/FBgn0053245 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG32605, CG33245, Ste:CG33245" "IPR016149:Casein kinase II, regulatory subunit, alpha-helical, IPR000704:Casein kinase II, regulatory subunit" CG33245 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0000840 fs(1)M27 female sterile (1) M27 http://flybase.org/reports/FBgn0000840 - gene - - - fs(1)M27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0260025 fonseca fonseca http://flybase.org/reports/FBgn0260025 gene - - - fonseca - - 11-Aug-17 DroID_v2017_08 - - - - - - chorion | germline clone FBgn0028889 tRNA:Leu-TAA-3-1 transfer RNA:Leucine-TAA 3-1 http://flybase.org/reports/FBgn0028889 tRNA_gene UUA codon-amino acid adaptor activity ; GO:0033403 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033403 cytosol ; GO:0005829 | inferred by curator from GO:0033403 "DtL[b], BG:DS03192.1, tRNA:leu, AE002690.trna13-LeuTAA, tRNA:L:TAA:AE002690, CR31831, tRNA[Leu], tRNA[LEU], chr2L.trna22-LeuTAA, tRNA-Leu-TAA-3-1, tRNA:Leu-TAA-3-1, tRNA:L:35C, UUA" - CR31831 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000144 Attenuated Attenuated http://flybase.org/reports/FBgn0000144 - gene - - - "Attenuated, At" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male fertile,female fertile,visible,dominant,good,fertile" wing FBgn0040230 dbo diablo http://flybase.org/reports/FBgn0040230 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 actin binding ; GO:0003779 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from direct assay neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype cell growth ; GO:0016049 | inferred from mutant phenotype regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from biological aspect of ancestor with PANTHER:PTN001973695 "Dm.DBO, DIABLO, Smac, CG6224, dbo, Dbo, henji" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR017096:BTB-kelch protein, IPR011043:Galactose oxidase/kelch, beta-propeller, IPR015915:Kelch-type beta propeller" CG6224 11-Aug-17 DroID_v2017_08 "Drer\klhl17, Drer\klhl20, Drer\klhl2, Drer\klhl18, Drer\klhl12, Drer\klhl5, Drer\klhl3" - "Cele\R12E2.1, Cele\kel-1, Cele\kel-3" "Xtro\klhl17, Xtro\klhl20, Xtro\klhl4, Xtro\klhl12, Xtro\klhl5" "Mmus\Klhl5, Mmus\Klhl1, Mmus\Klhl12, Mmus\Klhl2, Mmus\Klhl17, Mmus\Klhl20, Mmus\Klhl3, Mmus\Klhl4, Mmus\Klhl18" "Hsap\KLHL17, Hsap\KLHL5, Hsap\KLHL4, Hsap\KLHL3, Hsap\KLHL1, Hsap\KLHL12, Hsap\KLHL18, Hsap\KLHL20, Hsap\KLHL2" "planar polarity defective,viable,fertile" wing hair FBgn0035976 PGRP-LC Peptidoglycan recognition protein LC http://flybase.org/reports/FBgn0035976 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965, InterPro:IPR006619 protein dimerization activity ; GO:0046983 | inferred from direct assay peptidoglycan receptor activity ; GO:0016019 | non-traceable author statement N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues signaling pattern recognition receptor activity ; GO:0008329 | traceable author statement peptidoglycan receptor activity ; GO:0016019 | traceable author statement peptidoglycan receptor activity ; GO:0016019 | inferred from mutant phenotype peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b peptidoglycan binding ; GO:0042834 | non-traceable author statement peptidoglycan binding ; GO:0042834 | traceable author statement peptidoglycan binding ; GO:0042834 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with pirk protein dimerization activity ; GO:0046983 | non-traceable author statement" defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | traceable author statement regulation of humoral immune response ; GO:0002920 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement immune response ; GO:0006955 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype innate immune response ; GO:0045087 | traceable author statement positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype phagocytosis ; GO:0006909 | traceable author statement positive regulation of peptidoglycan recognition protein signaling pathway ; GO:0061059 | inferred from genetic interaction with PGRP-SD defense response to virus ; GO:0051607 | inferred from mutant phenotype innate immune response ; GO:0045087 | non-traceable author statement regulation of synaptic plasticity ; GO:0048167 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 response to bacterium ; GO:0009617 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from direct assay regulation of melanization defense response ; GO:0035007 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from genetic interaction with imd antibacterial humoral response ; GO:0019731 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay integral component of membrane ; GO:0016021 | traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement presynapse ; GO:0098793 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | inferred from direct assay spanning component of plasma membrane ; GO:0044214 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay "pgrp-lc, CG4432, ird7, PGRP-LCx, PGRP-LCa, tot, PGRP-LC, (PGRP)-LC, Dm PGRP-LC, PGRPLC, Pgrp-LC, pgrp lc" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR001965:Zinc finger, PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019787:Zinc finger, PHD-finger" CG4432 11-Aug-17 DroID_v2017_08 "Drer\pglyrp2, Drer\pglyrp5, Drer\pglyrp6" - - "Xtro\pglyrp2, Xtro\pglyrp1, Xtro\pglyrp1" "Mmus\Pglyrp1, Mmus\Pglyrp4, Mmus\Pglyrp3, Mmus\Pglyrp2" "Hsap\PGLYRP4, Hsap\PGLYRP3, Hsap\PGLYRP1, Hsap\PGLYRP2" "immune response defective,visible,short lived,conditional,viable,recessive,fertile,lethal,melanotic mass phenotype" wing FBgn0084374 E-3a Enhancer on chromosome 3-complementation group a http://flybase.org/reports/FBgn0084374 gene - - - E-3a - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,haltere" FBgn0039094 CG10184 - http://flybase.org/reports/FBgn0039094 protein_coding_gene L-allo-threonine aldolase activity ; GO:0008732 | inferred from biological aspect of ancestor with PANTHER:PTN000033149 glycine biosynthetic process ; GO:0006545 | inferred from biological aspect of ancestor with PANTHER:PTN000033149 threonine catabolic process ; GO:0006567 | inferred from biological aspect of ancestor with PANTHER:PTN000033149 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000033149 CG10184 "IPR001597:Aromatic amino acid beta-eliminating lyase/threonine aldolase, IPR023603:Threonine aldolase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase" CG10184 11-Aug-17 DroID_v2017_08 Drer\tha1 Scer\GLY1 Cele\R102.4 Xtro\tha1p Mmus\Tha1 - viable FBgn0036449 bmm brummer http://flybase.org/reports/FBgn0036449 protein_coding_gene triglyceride lipase activity ; GO:0004806 | inferred from direct assay lipid metabolic process ; GO:0006629 | inferred from mutant phenotype lipid catabolic process ; GO:0016042 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern positive regulation of lipid storage ; GO:0010884 | inferred from direct assay lipid homeostasis ; GO:0055088 | inferred from mutant phenotype triglyceride mobilization ; GO:0006642 | inferred from mutant phenotype triglyceride catabolic process ; GO:0019433 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000274414 lipid particle ; GO:0005811 | inferred from direct assay "bmm, CG5295, ATGL, Atgl, Bmm, BMM, ATGL/bmm" "IPR002641:Patatin-like phospholipase domain, IPR016035:Acyl transferase/acyl hydrolase/lysophospholipase, IPR033562:Patatin-like phospholipase domain-containing protein" CG5295 11-Aug-17 DroID_v2017_08 "Drer\pnpla3, Drer\pnpla2" - "Cele\B0524.2, Cele\atgl-1, Cele\D1054.1" "Xtro\pnpla2, Xtro\pnpla3, Xtro\pnpla4" "Mmus\Pnpla2, Mmus\Pnpla3, Mmus\Pnpla5, Mmus\Pnpla1" "Hsap\PNPLA4, Hsap\PNPLA3, Hsap\PNPLA5, Hsap\PNPLA2, Hsap\PNPLA1" "viable,short lived,recessive,long lived,stress response defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,visible" "adult fat body,embryonic/larval midgut,lipid droplet & larval oenocyteppl.PP,lipid droplet & larval oenocyteLsp2.PH,chaeta,supernumerary" FBgn0082686 E(ftz)20 E(ftz)20 http://flybase.org/reports/FBgn0082686 gene - - - "20, E(ftz)20" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005414 l(1)adl3 lethal (1) adl3 http://flybase.org/reports/FBgn0005414 - gene - - - "l(1)adl-3, l(1)adl3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile,short lived,gravitaxis defective,phototaxis defective,behavior defective" FBgn0039069 CG6763 - http://flybase.org/reports/FBgn0039069 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026" - CG6763 "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG6763 11-Aug-17 DroID_v2017_08 "Drer\c6ast4, Drer\he2, Drer\si:cabz01033205.3, Drer\LOC797085, Drer\mep1a.1, Drer\neto1l, Drer\si:ch211-167j6.5, Drer\mep1a.2, Drer\bmp1a, Drer\he1a, Drer\he1b, Drer\csmd1a, Drer\c6ast1, Drer\mep1b, Drer\npsn, Drer\LOC100003133, Drer\cdcp2, Drer\bmp1b, Drer\tnfaip6, Drer\tll1, Drer\si:ch73-40a17.3, Drer\c6ast3, Drer\neto1, Drer\neto2b" - "Cele\nas-2, Cele\Y19D10A.6, Cele\nas-9, Cele\nas-39, Cele\nas-13, Cele\ZC116.3, Cele\nas-6, Cele\nas-8, Cele\nas-15, Cele\nas-33, Cele\nas-14, Cele\nas-5, Cele\nas-4, Cele\nas-7, Cele\nas-1, Cele\nas-12" "Xtro\tnfaip6, Xtro\LOC100489456, Xtro\mep1a, Xtro\uvs.2, Xtro\accs, Xtro\cubn, Xtro\bmp1, Xtro\LOC100492324, Xtro\tll1, Xtro\mep1b, Xtro\tll2" "Mmus\Tnfaip6, Mmus\Adgrg6, Mmus\Tll2, Mmus\Cdcp2, Mmus\Astl, Mmus\Tll1, Mmus\Neto1, Mmus\Neto2, Mmus\Bmp1, Mmus\Mfrp, Mmus\Mep1b, Mmus\Mep1a, Mmus\Cubn" "Hsap\TLL1, Hsap\CUBN, Hsap\MEP1B, Hsap\ASTL, Hsap\CDCP2, Hsap\MEP1A, Hsap\TLL2, Hsap\NETO1, Hsap\BMP1, Hsap\NETO2, Hsap\MFRP, Hsap\ADGRG6, Hsap\TNFAIP6" viable FBgn0019726 l(2)46CFb lethal (2) 46CFb http://flybase.org/reports/FBgn0019726 - gene - - - "1.11, l(2)46CFb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029022 l(3)77ABj lethal (3) 77ABj http://flybase.org/reports/FBgn0029022 gene - - - l(3)77ABj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage" FBgn0062678 EP2087 EP2087 http://flybase.org/reports/FBgn0062678 gene - - - "EP(2)2087, EP2087" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053145 GalT1 "beta1,3-galactosyltransferase 1" http://flybase.org/reports/FBgn0053145 protein_coding_gene "beta-1,3-galactosyltransferase activity ; GO:0048531 | inferred from direct assay" protein N-linked glycosylation ; GO:0006487 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "CG33145, CG8976, GalT1, dbeta3GnT" "IPR002659:Glycosyl transferase, family 31" CG33145 11-Aug-17 DroID_v2017_08 "Drer\b3gnt7, Drer\b3galt1a, Drer\si:dkeyp-98a7.1, Drer\b3galnt2, Drer\b3gnt9, Drer\LOC565422, Drer\b3gnt3, Drer\si:ch211-126g16.11, Drer\b3gnt2a, Drer\b3gnt2b, Drer\b3galt1b, Drer\LOC100535930, Drer\zgc:194330, Drer\b3gnt2l, Drer\b3gnt7l, Drer\b3galt2, Drer\si:dkey-160o24.3, Drer\zgc:86586, Drer\zgc:194551, Drer\b3gnt5a, Drer\si:dkey-175m17.6, Drer\b3gnt5b" - "Cele\B0024.15, Cele\bus-2, Cele\E03H4.11, Cele\bus-17, Cele\C47F8.5, Cele\sqv-2" "Xtro\b3gnt5, Xtro\LOC100487553, Xtro\LOC100494986, Xtro\b3galt2, Xtro\LOC100493833, Xtro\b3galt4, Xtro\LOC100489267, Xtro\b3gnt3, Xtro\b3gnt6, Xtro\b3gnt2, Xtro\b3galt1, Xtro\b3gnt3, Xtro\b3galnt2, Xtro\LOC100494668, Xtro\b3gnt4" "Mmus\B3gnt6, Mmus\B3gnt3, Mmus\B3gnt8, Mmus\B3galnt1, Mmus\B3gnt5, Mmus\B3galnt2, Mmus\B3gnt9, Mmus\B3gnt4, Mmus\B3gnt2, Mmus\B3galt5, Mmus\B3galt2, Mmus\B3galt4, Mmus\B3galt1, Mmus\B3gnt7" "Hsap\B3GALT2, Hsap\B3GNT9, Hsap\B3GNT8, Hsap\B3GNT7, Hsap\B3GALNT1, Hsap\B3GALT4, Hsap\B3GALT5, Hsap\B3GALT1, Hsap\B3GNT6, Hsap\B3GNT3, Hsap\B3GALNT2, Hsap\B3GNT5, Hsap\B3GNT4, Hsap\B3GNT2" "viable,fertile" FBgn0046670 anon-38C.25 anon-38C.25 http://flybase.org/reports/FBgn0046670 gene - - - "38C.25, anon-38C.25" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004014 wi witty eye http://flybase.org/reports/FBgn0004014 - gene - - - wi - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,ommatidium,vibrissae" FBgn0083979 Ir10a Ionotropic receptor 10a http://flybase.org/reports/FBgn0083979 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir10a, CG12623, CG12624, CG34143, DmelIR10a, IR10a" - CG34143 11-Aug-17 DroID_v2017_08 - - - - - "Hsap\GRID1, Hsap\GRID2" viable FBgn0030486 Set2 SET domain containing 2 http://flybase.org/reports/FBgn0030486 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR017956 histone-lysine N-methyltransferase activity ; GO:0018024 | inferred from sequence or structural similarity with UniProtKB:Q9BZ95 histone methyltransferase activity (H3-K36 specific) ; GO:0046975 | inferred from mutant phenotype phosphoprotein binding ; GO:0051219 | inferred from physical interaction with RpII215 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR013257 histone methylation ; GO:0016571 | inferred from sequence or structural similarity with UniProtKB:Q9BZ95 instar larval development ; GO:0002168 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from genetic interaction with EcR histone H3-K36 methylation ; GO:0010452 | inferred from mutant phenotype" chromosome ; GO:0005694 | inferred from electronic annotation with InterPro:IPR013257 nucleus ; GO:0005634 | inferred from direct assay "SET2, Set2, CG1716, dSet2, set2, Hypb, dHypb" "IPR001202:WW domain, IPR001214:SET domain, IPR003616:Post-SET domain, IPR006560:AWS domain, IPR017956:AT hook, DNA-binding motif, IPR013257:SRI, Set2 Rpb1 interacting" CG1716 11-Aug-17 DroID_v2017_08 "Drer\phf3, Drer\setd2, Drer\nsd1b, Drer\whsc1, Drer\ash1l, Drer\whsc1l1, Drer\phf20l1, Drer\phf20b, Drer\kmt2d, Drer\kmt2e, Drer\setd1ba" "Scer\BYE1, Scer\SET3, Scer\SET1, Scer\SET4, Scer\CTI6, Scer\SET2" "Cele\set-19, Cele\mes-4, Cele\set-26, Cele\set-9, Cele\C16A11.4, Cele\set-5, Cele\set-20, Cele\lin-59, Cele\set-12, Cele\set-16, Cele\met-1" "Xtro\setd2, Xtro\setd1b" "Mmus\Whsc1l1, Mmus\Phf3, Mmus\Setd1a, Mmus\Ash1l, Mmus\Phf20l1, Mmus\Kmt2c, Mmus\Kmt2d, Mmus\Setd2, Mmus\Whsc1, Mmus\Setd5, Mmus\Nsd1, Mmus\Dido1, Mmus\Spocd1, Mmus\Kmt2e, Mmus\Setd1b" "Hsap\KMT2D, Hsap\KMT2E, Hsap\SETD5, Hsap\WHSC1, Hsap\DIDO1, Hsap\ASH1L, Hsap\PHF20L1, Hsap\SETD1B, Hsap\KMT2C, Hsap\SETD1A, Hsap\NSD1, Hsap\PHF20, Hsap\SETD2, Hsap\WHSC1L1" "visible,developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,viable,recessive,somatic clone" "wing,eye,somatic clone" FBgn0052462 CG32462 - http://flybase.org/reports/FBgn0052462 protein_coding_gene - - - "CG8220, CG32462" - CG32462 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0036207 CG10907 - http://flybase.org/reports/FBgn0036207 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG10907 "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG10907 11-Aug-17 DroID_v2017_08 Drer\cwc27 "Scer\CPR2, Scer\CWC27, Scer\CPR5" Cele\cyn-16 Xtro\cwc27 Mmus\Cwc27 Hsap\CWC27 viable FBgn0054038 CG34038 - http://flybase.org/reports/FBgn0054038 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1023, CG34038, Dm_2R:93795, Dm_2R:93799" IPR031941:Domain of unknown function DUF4773 CG34038 11-Aug-17 DroID_v2017_08 - - Cele\C09D4.2 - - - FBgn0019984 Gp14B Glycoprotein 14B http://flybase.org/reports/FBgn0019984 - gene - - - "gp, Gp14B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262458 mir-305 mir-305 stem loop http://flybase.org/reports/FBgn0262458 miRNA_gene - response to starvation ; GO:0042594 | inferred from mutant phenotype intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype cellular response to nutrient ; GO:0031670 | inferred from mutant phenotype regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from direct assay regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay - "mir-305, 305, dme-mir-305, miR-305, MIR-305, CR43032, CR33608, mir305, miR 305, miR305, MiR-305, dme-miR-305, miR-305-5p" - CR43032 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing FBgn0000423 ddl displaced-like http://flybase.org/reports/FBgn0000423 - gene - - - "dd[3], ddl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced,male sterile,male,poor" "adult head,eye,macrochaeta & adult thorax,wing" FBgn0035157 CG13894 - http://flybase.org/reports/FBgn0035157 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 - - "dmCG13894, CG13894" "IPR006600:HTH CenpB-type DNA-binding domain, IPR006612:Zinc finger, C2CH-type, IPR009057:Homeobox domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG13894 11-Aug-17 DroID_v2017_08 Drer\si:dkey-20i10.7 - - - Mmus\Thap11 - viable FBgn0040642 CG12545 - http://flybase.org/reports/FBgn0040642 protein_coding_gene - - - CG12545 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084765 1577 1577 http://flybase.org/reports/FBgn0084765 gene - - - 1577 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014918 anon-72ABb anon-72ABb http://flybase.org/reports/FBgn0014918 - gene - - - anon-72ABb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085267 CG34238 - http://flybase.org/reports/FBgn0085267 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34238 - CG34238 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250820 meigo medial glomeruli http://flybase.org/reports/FBgn0250820 protein_coding_gene UDP-galactose transmembrane transporter activity ; GO:0005459 | inferred from biological aspect of ancestor with PANTHER:PTN000081293 dendrite guidance ; GO:0070983 | inferred from mutant phenotype UDP-galactose transmembrane transport ; GO:0072334 | inferred from biological aspect of ancestor with PANTHER:PTN000081293 axon guidance ; GO:0007411 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype inferred from genetic interaction with Hsc70-3 protein N-linked glycosylation ; GO:0006487 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 "anon-EST:fe1H6, NEST:bs03h03, CG5802, meigo, Meigo" IPR013657:UAA transporter CG5802 11-Aug-17 DroID_v2017_08 "Drer\slc35b1, Drer\slc35b2" Scer\HUT1 "Cele\hut-1, Cele\pst-1" Xtro\slc35b1 "Mmus\Slc35b1, Mmus\Slc35b2" "Hsap\SLC35B1, Hsap\SLC35B2" FBgn0037320 CG14668 - http://flybase.org/reports/FBgn0037320 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14668 - CG14668 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0062524 l(3)88EFh lethal (3) 88EFh http://flybase.org/reports/FBgn0062524 gene - - - l(3)88EFh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic head,abdominal 8 ventral denticle belt" FBgn0066366 dru drujok http://flybase.org/reports/FBgn0066366 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available dru - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0065699 l(2)SH0624 lethal (2) SH0624 http://flybase.org/reports/FBgn0065699 gene - - - "l(2)SH0624, l(2)SH2 0624" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065649 l(2)SH0735 lethal (2) SH0735 http://flybase.org/reports/FBgn0065649 gene - - - "l(2)SH0735, l(2)SH2 0735" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025463 Bap60 Brahma associated protein 60kD http://flybase.org/reports/FBgn0025463 - protein_coding_gene "transcription coactivator activity ; GO:0003713 | inferred from mutant phenotype contributes_to DNA binding ; GO:0003677 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from mutant phenotype myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 RNA polymerase II transcription factor binding ; GO:0001085 | inferred from physical interaction with sisA inferred from physical interaction with sc protein binding ; GO:0005515 | inferred from physical interaction with mor transcription factor binding ; GO:0008134 | inferred from sequence or structural similarity with HGNC:11106" "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay positive regulation of heterochromatin assembly ; GO:0031453 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from genetic interaction with brm neuron development ; GO:0048666 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype" nuclear euchromatin ; GO:0005719 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay PBAF complex ; GO:0070604 | inferred from direct assay "BAP60, CG4303, i127, i133, BAPp60, Bap60, bap60, BAF60" "IPR003121:SWIB/MDM2 domain, IPR019835:SWIB domain" CG4303 11-Aug-17 DroID_v2017_08 "Drer\smarcd1, Drer\asic1b, Drer\asic2, Drer\smarcd2, Drer\smarcd3b, Drer\smarcd3a, Drer\asic1a" "Scer\TRI1, Scer\SNF12, Scer\RSC6, Scer\UAF30" "Cele\ham-3, Cele\acd-5, Cele\swsn-2.2, Cele\T24G10.2" "Xtro\smarcd2, Xtro\smarcd1, Xtro\smarcd3" "Mmus\Asic2, Mmus\Smarcd2, Mmus\Smarcd1, Mmus\Smarcd3, Mmus\Asic1" "Hsap\SMARCD1, Hsap\ASIC1, Hsap\SMARCD3, Hsap\SMARCD2, Hsap\ASIC2" "viable,lethal,recessive,germline clone,non-rescuable maternal effect,suppressor of variegation,dominant" embryonic/larval brain FBgn0261262 CG42613 - http://flybase.org/reports/FBgn0261262 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sleep ; GO:0030431 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "CG42613, CG5449, tld-like, CT33918, CT17110, CG14289, CG31149, CG31222" "IPR000859:CUB domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG42613 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-233f16.1, Drer\si:cabz01033205.3" - "Cele\sol-1, Cele\sol-2, Cele\lev-10" Xtro\mfrp "Mmus\Nrp2, Mmus\Mfrp" "Hsap\MFRP, Hsap\NRP2" DRSC13332 K -0.608738434 1.4562073 -0.171171736 1.493621161 2.15543771 2.346558651 FBgn0267663 CR46001 - http://flybase.org/reports/FBgn0267663 non_protein_coding_gene - - - CR46001 - CR46001 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001957 l(2)28Bc lethal (2) 28Bc http://flybase.org/reports/FBgn0001957 - gene - - - "O, l(2)28Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001686 l(1)ESHS7 lethal (1) ESHS7 http://flybase.org/reports/FBgn0001686 - gene - - - l(1)ESHS7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0064119 CG33934 - http://flybase.org/reports/FBgn0064119 protein_coding_gene succinate transmembrane transporter activity ; GO:0015141 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 citrate transmembrane transporter activity ; GO:0015137 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR001898 succinate transmembrane transport ; GO:0071422 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000815082 "CG4961, CG32921-ORFB, CG32921, anon-WO0140519.217, CG33934" IPR001898:Solute carrier family 13 CG33934 11-Aug-17 DroID_v2017_08 "Drer\slc13a2, Drer\slc13a3, Drer\slc13a5a, Drer\slc13a4, Drer\slc13a5b, Drer\slc13a1" "Scer\PHO90, Scer\PHO91, Scer\PHO87" "Cele\nac-1, Cele\B0285.6, Cele\nac-2, Cele\nac-3" "Xtro\slc13a3, Xtro\slc13a1, Xtro\slc13a4, Xtro\slc13a2, Xtro\slc13a5" "Mmus\Slc13a2, Mmus\Slc13a4, Mmus\Slc13a1, Mmus\Slc13a3, Mmus\Slc13a5" "Hsap\SLC13A2, Hsap\SLC13A1, Hsap\SLC13A5, Hsap\SLC13A3, Hsap\SLC13A4" FBgn0005712 l(1)TK115 lethal (1) TK115 http://flybase.org/reports/FBgn0005712 - gene - - - "l115, l(1)TK115" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0085710 CG41586 - http://flybase.org/reports/FBgn0085710 protein_coding_gene - - - CG41586 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262795 CR43176 - http://flybase.org/reports/FBgn0262795 pseudogene_attribute - - - "CG43176, CR43176, CG40648, Mst77Y" - CR43176 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000573 elr elliptical rough http://flybase.org/reports/FBgn0000573 - gene - - - elr - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile" "wing,eye" FBgn0266119 TART-A\RT reverse transcriptase http://flybase.org/reports/FBgn0266119 transposable_element_gene - - - TART-A\RT - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086045 snoRNA:Me18S-A627 - http://flybase.org/reports/FBgn0086045 snoRNA_gene - - - "snoRNA:Me18S-A627, Me18S-Am627, CR34674" - CR34674 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014284 l(3)64Ac lethal (3) 64Ac http://flybase.org/reports/FBgn0014284 - gene - - - l(3)64Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032538 CG16885 - http://flybase.org/reports/FBgn0032538 protein_coding_gene - - - "CG18634, CG16885, vajk-2" - CG16885 11-Aug-17 DroID_v2017_08 - - Cele\T26C11.2 - Mmus\Ggn "Hsap\GGN, Hsap\TPRX1" DRSC02540 E -0.87157237 0.185291407 1.86025452 -0.635924003 0.454532625 -0.844055447 FBgn0003549 su(B)4 suppressor of Bar on 4 http://flybase.org/reports/FBgn0003549 - gene - - - "m(B)4, su(B)4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025119 su(RpII140[Z36])S9 su(RpII140[Z36])S9 http://flybase.org/reports/FBgn0025119 - gene - - - "Z36[S9], su(RpII140[Z36])S9" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260036 33Q1 - http://flybase.org/reports/FBgn0260036 gene - - - 33Q1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0029970 Nek2 Nek2 http://flybase.org/reports/FBgn0029970 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay" protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from direct assay positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with dsh inferred from genetic interaction with wg midbody ; GO:0030496 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "CG17256, DmNek2, NEK2, Nek2, Dm Nek2, dNek2" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG17256 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-285c6.3, Drer\si:dkey-192d15.2, Drer\si:ch211-217i17.1, Drer\LOC100536894, Drer\nek7, Drer\nek12, Drer\nek11, Drer\nek4, Drer\nek2, Drer\nek1, Drer\nek8, Drer\LOC101885992, Drer\si:ch211-285c6.2" Scer\KIN3 "Cele\nekl-2, Cele\T07F12.4, Cele\nekl-3" "Xtro\nek5, Xtro\nek8, Xtro\nek2, Xtro\nek9, Xtro\nek1, Xtro\nek3, Xtro\stkld1, Xtro\nek4, Xtro\nek10" "Mmus\Stkld1, Mmus\Nek7, Mmus\Nek11, Mmus\Nek3, Mmus\Nek1, Mmus\Nek4, Mmus\Nek8, Mmus\Nek9, Mmus\Nek5, Mmus\Nek6, Mmus\Nek2, Mmus\Nek10" "Hsap\NEK7, Hsap\NEK4, Hsap\NEK2, Hsap\NEK11, Hsap\NEK8, Hsap\STKLD1, Hsap\NEK9, Hsap\NEK6, Hsap\NEK1, Hsap\NEK3, Hsap\NEK10, Hsap\NEK5" "mitotic cell cycle defective,cytokinesis defective,visible,viable,size defective" "mitotic metaphase & cytoplasm,mitotic anaphase & cytoplasm,mitotic metaphase & spindle,mitotic anaphase & spindle,spindle,centrosome | supernumerary,microtubule,centrosome,mitotic anaphase,mitotic telophase,mitotic telophase & midbody,wing,chaeta,ectopic,centrosomeptc-559.1,wing disc,mesothoracic tergum,scutellum,eye,ommatidium" DRSC18124 K 0.206720188 0.732992709 -0.191069027 0.012796813 1.942243985 -0.117738817 FBgn0052072 Elo68alpha Elongase 68alpha http://flybase.org/reports/FBgn0052072 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from direct assay fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond "pheromone biosynthetic process ; GO:0042811 | inferred from mutant phenotype fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond fatty acid elongation, unsaturated fatty acid ; GO:0019368 | inferred from direct assay long-chain fatty acid biosynthetic process ; GO:0042759 | inferred from direct assay" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "elo68alpha, CG6261, Elo68alpha, CG32072" "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG32072 11-Aug-17 DroID_v2017_08 "Drer\elovl8b, Drer\elovl8a, Drer\elovl2, Drer\elovl4b, Drer\elovl4a, Drer\dhrs7, Drer\zgc:101858, Drer\elovl1b, Drer\hsd17b8, Drer\elovl1a, Drer\elovl7a, Drer\elovl5, Drer\elovl7b" "Scer\ELO3, Scer\ELO1, Scer\ELO2" "Cele\F25D1.5, Cele\dhs-11, Cele\elo-2, Cele\dhs-25, Cele\Y47G6A.21, Cele\elo-7, Cele\C06E4.3, Cele\Y47G6A.22, Cele\dhs-14, Cele\F28H7.2, Cele\F26D2.15, Cele\ZK829.1" "Xtro\elovl7, Xtro\cbr4, Xtro\dhrs7, Xtro\elovl2, Xtro\elovl5, Xtro\MGC79752, Xtro\hsd17b8, Xtro\elovl1" "Mmus\H2-Ke6, Mmus\Elovl7, Mmus\Dhrs7, Mmus\Elovl4, Mmus\Elovl5, Mmus\Elovl1, Mmus\Elovl2, Mmus\Cbr4" "Hsap\ELOVL7, Hsap\HSD17B8, Hsap\ELOVL2, Hsap\ELOVL4, Hsap\ELOVL5, Hsap\DHRS7, Hsap\ELOVL1, Hsap\CBR4" viable FBgn0002529 Lap-A Leucine aminopeptidase A http://flybase.org/reports/FBgn0002529 - gene - - - "LAP, Lap, LAP-A, LapA, Lap-A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "electrophoretic variant,slow,fast" FBgn0023139 WppD White prepupal locus D http://flybase.org/reports/FBgn0023139 - gene - - - "4, 20, 13, WppD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060921 l(3)S042412 lethal (3) S042412 http://flybase.org/reports/FBgn0060921 gene - - - "0424/12, l(3)S042412" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0024517 l(3)j1B10 lethal (3) j1B10 http://flybase.org/reports/FBgn0024517 - gene - - - l(3)j1B10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050484 CG30484 - http://flybase.org/reports/FBgn0050484 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13342, CG30484" - CG30484 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030540 CG11581 - http://flybase.org/reports/FBgn0030540 protein_coding_gene - - - CG11581 - CG11581 11-Aug-17 DroID_v2017_08 - - Cele\rol-6 - - - "partially lethal - majority die,some die during pupal stage" FBgn0262452 mir-79 mir-79 stem loop http://flybase.org/reports/FBgn0262452 miRNA_gene - - - "mir-79, 79, dme-mir-79, miR-79, CR43019, CR33570, MiR-79, dme-miR-79-3p, dme-miR-79" - CR43019 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage "viable,visible,male,lethal" "wing,male,wing disc" FBgn0260303 GSd483 - http://flybase.org/reports/FBgn0260303 gene - - - GSd483 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011121 l(1)Q82 lethal (1) Q82 http://flybase.org/reports/FBgn0011121 FBgn0010210 gene - - - l(1)Q82 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034904 CG15800 - http://flybase.org/reports/FBgn0034904 protein_coding_gene - "ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR016072, InterPro:IPR016073" - "CG15800, SkpG" "IPR011333:SKP1/BTB/POZ domain, IPR016072:SKP1 component, dimerisation, IPR016073:SKP1 component, POZ domain, IPR001232:S-phase kinase-associated protein 1-like" CG15800 11-Aug-17 DroID_v2017_08 Drer\skp1 Scer\SKP1 "Cele\skr-6, Cele\skr-3, Cele\skr-2, Cele\skr-19, Cele\skr-16, Cele\skr-9, Cele\skr-7, Cele\skr-12, Cele\skr-8, Cele\skr-20, Cele\skr-10, Cele\C16D2.1, Cele\skr-4, Cele\skr-13, Cele\skr-18, Cele\skr-1, Cele\skr-21, Cele\skr-14, Cele\skr-17, Cele\skr-5, Cele\skr-15" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 viable FBgn0035396 CG14953 - http://flybase.org/reports/FBgn0035396 protein_coding_gene - - - CG14953 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017366 l(3)89Bp lethal (3) 89Bp http://flybase.org/reports/FBgn0017366 - gene - - - "l(3)89Bn, l(3)89Bp" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026255 clumsy clumsy http://flybase.org/reports/FBgn0026255 FBgn0032933 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity with HGNC:4579 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 regulation of synaptic activity ; GO:0060025 | inferred from sequence or structural similarity with GluRIIA plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with GluRIIA "CG8681, GluR39B, CT9037, clumsy, Clumsy, Dmelclumsy" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG8681 11-Aug-17 DroID_v2017_08 "Drer\gria2b, Drer\gria4b, Drer\grik4, Drer\gria3b, Drer\si:ch211-251b21.1, Drer\grik1a, Drer\gria2a, Drer\grik1b, Drer\LOC100334689, Drer\si:dkey-183j2.10, Drer\grik5, Drer\grik2, Drer\LOC100331381, Drer\gria3a, Drer\gria1a" - "Cele\glr-4, Cele\glr-8, Cele\glr-5, Cele\glr-6, Cele\glr-3" "Xtro\grik5, Xtro\gria3, Xtro\grik1, Xtro\grik4, Xtro\gria4, Xtro\gria1" "Mmus\Gria3, Mmus\Grik3, Mmus\Grik5, Mmus\Grik4, Mmus\Grik1, Mmus\Gria1, Mmus\Grik2, Mmus\Gria2, Mmus\Gria4" "Hsap\GRID2, Hsap\GRIK4, Hsap\GRIA3, Hsap\GRIK2, Hsap\GRIK1, Hsap\GRIA1, Hsap\GRIK3, Hsap\GRIA4, Hsap\GRIK5, Hsap\GRIA2" "phototaxis defective,viable,lethal" FBgn0053508 ppk13 pickpocket 13 http://flybase.org/reports/FBgn0053508 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG14398, PPK13, CG33508, ppk13" IPR001873:Epithelial sodium channel CG33508 11-Aug-17 DroID_v2017_08 "Drer\asic4b, Drer\asic2, Drer\asic1c, Drer\asic4a, Drer\asic1a, Drer\asic1b" - "Cele\acd-1, Cele\acd-4, Cele\acd-5, Cele\delm-1, Cele\flr-1, Cele\asic-2, Cele\del-4, Cele\del-7, Cele\del-1, Cele\unc-105, Cele\delm-2, Cele\acd-3, Cele\del-8, Cele\acd-2, Cele\mec-10" "Xtro\asic5, Xtro\scnn1a, Xtro\scnn1b, Xtro\asic4, Xtro\scnn1d, Xtro\asic1, Xtro\scnn1g" "Mmus\Asic5, Mmus\Asic4, Mmus\Asic2, Mmus\Scnn1g, Mmus\Asic3, Mmus\Scnn1a, Mmus\Scnn1b, Mmus\Asic1" "Hsap\SCNN1D, Hsap\ASIC4, Hsap\ASIC5, Hsap\SCNN1A, Hsap\ASIC2, Hsap\ASIC1, Hsap\SCNN1G, Hsap\SCNN1B, Hsap\ASIC3" viable FBgn0033379 Mys45A Mystery 45A http://flybase.org/reports/FBgn0033379 protein_coding_gene - ribosomal large subunit export from nucleus ; GO:0000055 | inferred from electronic annotation with InterPro:IPR027312 ribosomal large subunit biogenesis ; GO:0042273 | inferred from electronic annotation with InterPro:IPR027312 neurogenesis ; GO:0022008 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from biological aspect of ancestor with PANTHER:PTN000296326 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000296326 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q9NVU7 "CG8070, anon-WO0118547.170, Mys45A, Mys45a, Mys-45A" "IPR007949:SDA1 domain, IPR012977:Uncharacterised domain NUC130/133, N-terminal, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR027312:Sda1" CG8070 11-Aug-17 DroID_v2017_08 Drer\sdad1 Scer\SDA1 Cele\pro-3 Xtro\sdad1 Mmus\Sdad1 Hsap\SDAD1 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC07067 E -0.992750705 -0.336367895 1.712238022 -1.179810931 0.825241156 0.109580337 FBgn0267170 CR45610 - http://flybase.org/reports/FBgn0267170 non_protein_coding_gene - - - CR45610 - CR45610 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039444 TwdlD TweedleD http://flybase.org/reports/FBgn0039444 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from direct assay chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype body morphogenesis ; GO:0010171 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from direct assay "TwdlD, CG14243" IPR004145:Domain of unknown function DUF243 CG14243 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265899 CR44688 - http://flybase.org/reports/FBgn0265899 non_protein_coding_gene - - - "CR44688, lincRNA.656" - CR44688 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267972 Der-1 Derlin-1 http://flybase.org/reports/FBgn0267972 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR022764 peptidase activity ; GO:0008233 | inferred from sequence or structural similarity with UniProtKB:P38307 misfolded or incompletely synthesized protein catabolic process ; GO:0006515 | inferred from sequence or structural similarity with UniProtKB:P38307 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from sequence or structural similarity with UniProtKB:P38307 positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR022764 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with UniProtKB:P38307 "CG10908, Derlin-1, Der-1, l(2)SH1964, l(2)SH2 1964" "IPR007599:Derlin, IPR022764:Peptidase S54, rhomboid domain" CG10908 11-Aug-17 DroID_v2017_08 "Drer\derl3, Drer\abhd11, Drer\derl1, Drer\derl2" "Scer\DER1, Scer\DFM1" "Cele\R151.6, Cele\abhd-11.2, Cele\abhd-11.1, Cele\cup-2" "Xtro\derl1, Xtro\derl2, Xtro\abhd11" "Mmus\Abhd11, Mmus\Derl3, Mmus\Derl1, Mmus\Derl2" "Hsap\ABHD11, Hsap\DERL3, Hsap\DERL2, Hsap\DERL1" FBgn0005684 cpy clumpy http://flybase.org/reports/FBgn0005684 - gene - - - cpy - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "eye,rhabdomere,photoreceptor cell R2,photoreceptor cell R4" FBgn0001706 l(1)ESHS27 lethal (1) ESHS27 http://flybase.org/reports/FBgn0001706 - gene - - - l(1)ESHS27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041202 Lipocalin Lipocalin http://flybase.org/reports/FBgn0041202 gene - - - "Dmel.Lip, Lipocalin" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029702 CG15572 - http://flybase.org/reports/FBgn0029702 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15572 IPR031957:Domain of unknown function DUF4777 CG15572 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263265 com2 - http://flybase.org/reports/FBgn0263265 gene - gonad development ; GO:0008406 | inferred from mutant phenotype - com2 - - 11-Aug-17 DroID_v2017_08 - - - - - - gonad FBgn0058386 CG40386 - http://flybase.org/reports/FBgn0058386 protein_coding_gene - - - CG40386 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000755 fs(1)A436 female sterile (1) A436 http://flybase.org/reports/FBgn0000755 - gene - - - fs(1)A436 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect" embryo FBgn0267626 CR45964 - http://flybase.org/reports/FBgn0267626 non_protein_coding_gene - - - CR45964 - CR45964 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051104 CG31104 - http://flybase.org/reports/FBgn0051104 protein_coding_gene - - - "CG13657, CG31104" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG31104 11-Aug-17 DroID_v2017_08 - - "Cele\dhs-27, Cele\D1044.1, Cele\C29F7.2, Cele\C29F7.1, Cele\nhr-246, Cele\H06H21.8" - - - viable FBgn0043962 anon-19Ca anon-19Ca http://flybase.org/reports/FBgn0043962 gene - - - anon-19Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035270 CG13933 - http://flybase.org/reports/FBgn0035270 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001496 ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 "dmASBa, CG13933" "IPR001496:SOCS box domain, IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG13933 11-Aug-17 DroID_v2017_08 Drer\asb18 - Cele\unc-44 "Xtro\asb13, Xtro\asb12" Mmus\Ripk4 Hsap\RIPK4 viable FBgn0024893 dud dud http://flybase.org/reports/FBgn0024893 - gene - Nebenkern assembly ; GO:0007287 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype - "ms(2)Hb328, dud" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,partially lethal - majority die" "spermatozoon,primary spermatocyte cyst,spermatid & nucleus,Nebenkern" FBgn0037436 Hr83 Hormone receptor 83 http://flybase.org/reports/FBgn0037436 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR013088" nucleolus ; GO:0005730 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DHR83, Hr83, CG10296, NR2E5" "IPR001628:Zinc finger, nuclear hormone receptor-type, IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR013088:Zinc finger, NHR/GATA-type" CG10296 11-Aug-17 DroID_v2017_08 "Drer\nr2e1, Drer\esr2a, Drer\pparaa, Drer\nr2f6a, Drer\nr0b1, Drer\rxraa, Drer\rarab, Drer\esrra, Drer\ppardb, Drer\nr2f1a, Drer\pparg, Drer\rxrab, Drer\thrab, Drer\nr5a1a, Drer\nr2e3, Drer\nr1h4, Drer\pparda, Drer\esr2b, Drer\pparab, Drer\nr1h5, Drer\esr1, Drer\vdrb, Drer\nr2c1, Drer\nr2f1b, Drer\nr2f2, Drer\raraa, Drer\nr6a1b, Drer\nr2c2, Drer\nr2f5, Drer\esrrd, Drer\rargb, Drer\nr2f6b, Drer\pgr, Drer\nr0b2a, Drer\nr3c1, Drer\esrrga, Drer\rxrba, Drer\rxrga, Drer\nr0b2b, Drer\rxrbb, Drer\vdra, Drer\nr1i2, Drer\ar" - "Cele\nhr-38, Cele\nhr-87, Cele\nhr-92, Cele\nhr-108, Cele\nhr-239, Cele\nhr-111, Cele\nhr-237, Cele\nhr-236, Cele\nhr-162, Cele\nhr-150, Cele\fax-1, Cele\nhr-114, Cele\nhr-226, Cele\nhr-88" "Xtro\rara, Xtro\esrrg, Xtro\esr1, Xtro\nr2e1, Xtro\rxrg, Xtro\nr1h5, Xtro\pgr, Xtro\esr2, Xtro\rxrb, Xtro\nr2c2, Xtro\nr2f1, Xtro\ppara, Xtro\vdr, Xtro\esrrgr, Xtro\nr0b1, Xtro\esrra, Xtro\nr2c1, Xtro\nr3c2, Xtro\nr1h2, Xtro\nr0b2, Xtro\ppard, Xtro\nr2f6, Xtro\rarb, Xtro\esrrb, Xtro\nr1i2, Xtro\nr2e3, Xtro\pparg, Xtro\nr3c1, Xtro\rxra, Xtro\ar, Xtro\nr6a1, Xtro\nr2f2, Xtro\rarg, Xtro\nr2f5, Xtro\thrb" "Mmus\Nr2f2, Mmus\Ppara, Mmus\Nr1h2, Mmus\Ppard, Mmus\Rxrb, Mmus\Nr6a1, Mmus\Nr1h5, Mmus\Nr1i2, Mmus\Nr0b1, Mmus\Nr2c1, Mmus\Rxra, Mmus\Esrrb, Mmus\Esrrg, Mmus\Esr1, Mmus\Pparg, Mmus\Rxrg, Mmus\Esrra, Mmus\Nr1i3, Mmus\Nr2e1, Mmus\Nr3c1, Mmus\Nr0b2, Mmus\Rarb, Mmus\Ar, Mmus\Nr2c2, Mmus\Rara, Mmus\Nr1h4, Mmus\Vdr, Mmus\Thrb, Mmus\Rarg, Mmus\Thra, Mmus\Nr2f1, Mmus\Nr2f6, Mmus\Nr1h3, Mmus\Nr2e3, Mmus\Nr3c2, Mmus\Esr2, Mmus\Pgr" "Hsap\RXRG, Hsap\NR2F6, Hsap\NR3C1, Hsap\THRA, Hsap\VDR, Hsap\NR1H4, Hsap\NR0B2, Hsap\NR1I2, Hsap\RARA, Hsap\NR0B1, Hsap\ESRRA, Hsap\THRB, Hsap\ESR1, Hsap\PPARG, Hsap\AR, Hsap\RXRB, Hsap\NR2F1, Hsap\NR2F2, Hsap\NR6A1, Hsap\NR1I3, Hsap\PPARA, Hsap\ESRRG, Hsap\NR2C1, Hsap\NR2C2, Hsap\RXRA, Hsap\PPARD, Hsap\RARB, Hsap\ESR2, Hsap\NR1H2, Hsap\NR1H3, Hsap\ESRRB, Hsap\NR2E1, Hsap\NR2E3, Hsap\NR3C2, Hsap\PGR, Hsap\RARG" "viable,fertile" DRSC25662 K 0.873255297 0.386978935 -0.107382817 -0.185233339 -0.091751032 -1.634616063 FBgn0020527 mit(3)R2 mitotic R2 http://flybase.org/reports/FBgn0020527 - gene - - - mit(3)R2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034248 CG14483 - http://flybase.org/reports/FBgn0034248 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN002143768 mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from biological aspect of ancestor with PANTHER:PTN002143768 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN002143768 CG14483 IPR018625:Protein Pet100 CG14483 11-Aug-17 DroID_v2017_08 Drer\pet100 Scer\PET100 Cele\Y53F4B.14 - Mmus\Pet100 Hsap\PET100 viable FBgn0262260 mir-2282 mir-2282 stem loop http://flybase.org/reports/FBgn0262260 miRNA_gene - - - "mir-2282, CR42967, miR-2282, dme-mir-2282" - CR42967 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039415 CG6142 - http://flybase.org/reports/FBgn0039415 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753" - CG6142 "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG6142 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0024764 EC19 EC19 http://flybase.org/reports/FBgn0024764 - gene - - - EC19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,non-enhancer of variegation" FBgn0040754 CG17059 - http://flybase.org/reports/FBgn0040754 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay positive regulation of cell proliferation ; GO:0008284 | inferred from sequence or structural similarity with UniProtKB:Q8WXC6 cellular response to UV ; GO:0034644 | inferred from sequence or structural similarity with UniProtKB:Q8WXC6 COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity with UniProtKB:Q8WXC6 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with UniProtKB:Q8WXC6 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q8WXC6 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:Q8WXC6 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q8WXC6 "BcDNA:GH04581, CG17059" IPR029391:Myeloma-overexpressed 2-like CG17059 11-Aug-17 DroID_v2017_08 Drer\myeov2 - - Xtro\myeov2 Mmus\Myeov2 Hsap\COPS9 viable FBgn0052544 CG32544 - http://flybase.org/reports/FBgn0052544 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32544 - CG32544 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040228 DCTN5-p25 "Dynactin 5, p25 subunit" http://flybase.org/reports/FBgn0040228 protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity retrograde axonal transport ; GO:0008090 | inferred from mutant phenotype dynactin complex ; GO:0005869 | inferred from sequence or structural similarity "p25, CG10846, DS00929.1, l(2)35Bf, BG:DS00929.1, l(2)br2, br2, C4, dyn-p25, DCTN5, DCTN5-p25, P25" "IPR011004:Trimeric LpxA-like, IPR001451:Hexapeptide repeat" CG10846 11-Aug-17 DroID_v2017_08 Drer\dctn5 - Cele\dnc-5 Xtro\dctn5 Mmus\Dctn5 Hsap\DCTN5 "lethal,recessive,male sterile,female sterile,partially lethal - majority die,visible" "macrochaeta & thoraxA400),macrochaeta & thorax64j),macrochaeta,wing,mesothoracic tergum" FBgn0005517 l(1)2Dh lethal (1) 2Dh http://flybase.org/reports/FBgn0005517 - gene - - - "N5, N2, l(1)N5, l(1)2Dh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051125 CG31125 - http://flybase.org/reports/FBgn0051125 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD02419, CG31125" - CG31125 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC25124 IK 0.497681195 3.064095326 1.299976598 1.355885029 1.82492997 0.318881681 FBgn0036808 Dic4 Dicarboxylate carrier 4 http://flybase.org/reports/FBgn0036808 protein_coding_gene sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 dicarboxylic acid transmembrane transporter activity ; GO:0005310 | NOT inferred from direct assay phosphate transmembrane transporter activity ; GO:1901677 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transmembrane transporter activity ; GO:0015117 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transport ; GO:0015709 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 phosphate ion transmembrane transport ; GO:0035435 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 dicarboxylic acid transport ; GO:0006835 | NOT inferred from direct assay mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 sulfate transport ; GO:0008272 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 mitochondrion ; GO:0005739 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG18363, Dic4, DmDic4p" "IPR002067:Mitochondrial carrier protein, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG18363 11-Aug-17 DroID_v2017_08 "Drer\slc25a10, Drer\si:ch1073-100f3.2, Drer\slc25a11" Scer\DIC1 Cele\slc-25A10 "Xtro\slc25a10, Xtro\ucp2, Xtro\rangrf" "Mmus\Slc25a11, Mmus\Slc25a10" "Hsap\MRPL12, Hsap\SLC25A11, Hsap\SLC25A10" viable FBgn0005562 M(3)65F Minute (3) 65F http://flybase.org/reports/FBgn0005562 "FBgn0002613, FBgn0002614" gene - - - "M(3)h, M(3)h[S37], M(3L)h, M(3)S37, M(3)66A, M(3)65F" - - 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,dominant,visible,Minute" macrochaeta FBgn0030761 CG9784 - http://flybase.org/reports/FBgn0030761 protein_coding_gene inositol trisphosphate phosphatase activity ; GO:0046030 | non-traceable author statement phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from electronic annotation with InterPro:IPR000300 dephosphorylation ; GO:0016311 | non-traceable author statement - "IPP, CG9784, lincRNA.S9473" "IPR000300:Inositol polyphosphate-related phosphatase, IPR005135:Endonuclease/exonuclease/phosphatase" CG9784 11-Aug-17 DroID_v2017_08 "Drer\inpp5ka, Drer\inpp5jb, Drer\inpp5j, Drer\inppl1a, Drer\inpp5e, Drer\sh2d1aa, Drer\inpp5d, Drer\inpp5l, Drer\inppl1b, Drer\inpp5kb, Drer\inpp5b, Drer\ocrl" "Scer\INP54, Scer\INP51, Scer\INP52, Scer\INP53" "Cele\cil-1, Cele\ipp-5" "Xtro\inpp5k, Xtro\inpp5d, Xtro\inpp5j, Xtro\inpp5a.1, Xtro\sec16a, Xtro\inpp5b" "Mmus\Sh2d1a, Mmus\Ocrl, Mmus\Inpp5e, Mmus\Inpp5j, Mmus\Inpp5k, Mmus\Inpp5d, Mmus\Sh2d1b1, Mmus\Inpp5a, Mmus\Sh2d1b2, Mmus\Inppl1, Mmus\Inpp5b" "Hsap\INPP5E, Hsap\OCRL, Hsap\INPP5B, Hsap\INPP5J, Hsap\INPPL1, Hsap\INPP5K, Hsap\SH2D1B, Hsap\INPP5D, Hsap\INPP5A" viable "synapse,neuromuscular junction" FBgn0045058 fs(1)162 female sterile (1) 162 http://flybase.org/reports/FBgn0045058 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)162 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "ovary,egg" FBgn0032439 Ref2 RNA and export factor binding protein 2 http://flybase.org/reports/FBgn0032439 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "CG17031, REF2, cg17031, Ref2, ref2" IPR000504:RNA recognition motif domain CG17031 11-Aug-17 DroID_v2017_08 "Drer\poldip3, Drer\myef2, Drer\alyref, Drer\srsf5a, Drer\rbm46" Scer\YRA1 "Cele\aly-1, Cele\C02B10.4, Cele\Y37E11AL.9, Cele\aly-2, Cele\aly-3" "Xtro\alyref, Xtro\poldip3" "Mmus\Gm4302, Mmus\Gm4301, Mmus\Gm21293, Mmus\Gm21304, Mmus\Gm4340, Mmus\Alyref2, Mmus\Alyref, Mmus\Gm8764, Mmus\Gm21312, Mmus\Gm4305, Mmus\Gm4312, Mmus\Poldip3, Mmus\Gm20765, Mmus\Gm4303, Mmus\Gm4307, Mmus\Gm6763" "Hsap\A1CF, Hsap\ALYREF, Hsap\POLDIP3" viable FBgn0085543 CG40950 - http://flybase.org/reports/FBgn0085543 protein_coding_gene - - - CG40950 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064214 T:Rep-en Repressor domain of en http://flybase.org/reports/FBgn0064214 engineered_tag - - - "T:Rep-en, T:en" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019753 l(1)815-12 lethal (1) 815-12 http://flybase.org/reports/FBgn0019753 - gene - - - l(1)815-12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082953 snoRNA:Psi28S-612 snoRNA:Psi28S-612 http://flybase.org/reports/FBgn0082953 snoRNA_gene - - - "snoRNA:Psi28S-612, psi28s-612, CR34640" - CR34640 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026640 l(2)k09315 lethal (2) k09315 http://flybase.org/reports/FBgn0026640 - gene - - - l(2)k09315 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031460 CG15399 - http://flybase.org/reports/FBgn0031460 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15399 IPR027417:P-loop containing nucleoside triphosphate hydrolase CG15399 11-Aug-17 DroID_v2017_08 Drer\rabl3 Scer\YPT10 Cele\Y116A8C.10 Xtro\rabl3 Mmus\Rabl3 Hsap\RABL3 "partially lethal - majority die,some die during pupal stage" DRSC00413 E -1.037797951 -0.62101112 1.703992514 -1.937104701 FBgn0086044 snoRNA:Me28S-U1688 - http://flybase.org/reports/FBgn0086044 snoRNA_gene - - - "snoRNA:Me28S-U1688, Me28S-Um1688, CR34673" - CR34673 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263199 Galk Galactokinase http://flybase.org/reports/FBgn0263199 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000705, InterPro:IPR006203, InterPro:IPR006204, InterPro:IPR006206 galactokinase activity ; GO:0004335 | inferred from sequence or structural similarity with HGNC:4118" carbohydrate phosphorylation ; GO:0046835 | inferred from electronic annotation with InterPro:IPR000705 galactose metabolic process ; GO:0006012 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:4118 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:4118 membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:4118 "CG5288, Galk, GALK, dGALK, CT16885, cg5288" "IPR000705:Galactokinase, IPR006203:GHMP kinase, ATP-binding, conserved site, IPR006204:GHMP kinase N-terminal domain, IPR006206:Mevalonate/galactokinase, IPR013750:GHMP kinase, C-terminal domain, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR019539:Galactokinase galactose-binding domain, IPR019741:Galactokinase, conserved site, IPR020568:Ribosomal protein S5 domain 2-type fold" CG5288 11-Aug-17 DroID_v2017_08 "Drer\galk2, Drer\galk1" "Scer\GAL3, Scer\GAL1" Cele\tag-96 "Xtro\galk2, Xtro\galk1" "Mmus\Galk1, Mmus\Galk2" "Hsap\GALK1, Hsap\GALK2" FBgn0040305 MTF-1 Metal response element-binding Transcription Factor-1 http://flybase.org/reports/FBgn0040305 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay" stress response to cadmium ion ; GO:1990170 | inferred from mutant phenotype response to metal ion ; GO:0010038 | inferred from mutant phenotype cellular metal ion homeostasis ; GO:0006875 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from mutant phenotype zinc ion homeostasis ; GO:0055069 | inferred from mutant phenotype response to copper ion ; GO:0046688 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "dMTF-1, mtf-1, CG3743, anon-WO0118547.411, MTF-1, Mtf-1" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011989:Armadillo-like helical" CG3743 11-Aug-17 DroID_v2017_08 "Drer\mtf1, Drer\zgc:174574" Scer\CRZ1 Cele\blmp-1 Xtro\mtf1 Mmus\Mtf1 "Hsap\GLIS1, Hsap\MTF1, Hsap\GLIS2" "chemical sensitive,short lived,chemical conditional,chemical resistant,long lived,oxidative stress response defective,starvation stress response defective,calorie restriction conditional,female sterile,visible,partially lethal - majority die,developmental rate defective,viable,fertile,recessive,lethal - all die before end of larval stage,some die during third instar larval stage,some die during pupal stage" "wing,mesothoracic tergum" DRSC21341 K -0.616102367 1.136536646 -0.471056923 -0.580371751 2.130648884 -0.061581028 FBgn0066344 laska laska http://flybase.org/reports/FBgn0066344 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available laska - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0042084 Bap26 Brahma associated protein 26kD http://flybase.org/reports/FBgn0042084 gene - - brahma complex ; GO:0035060 | colocalizes_with inferred from direct assay "BAP26, Bap26" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033913 CG8468 - http://flybase.org/reports/FBgn0033913 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG8468 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8468 11-Aug-17 DroID_v2017_08 "Drer\slc16a4, Drer\slc16a6b, Drer\LOC103911912, Drer\slc16a12b, Drer\slc16a6a, Drer\zgc:114041, Drer\mfsd6b, Drer\si:dkey-246g23.4, Drer\slc16a12a, Drer\slc16a13, Drer\slc16a9b, Drer\slc16a9a" "Scer\MCH2, Scer\MCH4, Scer\ESBP6, Scer\ATG22, Scer\MCH5" "Cele\mct-6, Cele\mct-1, Cele\mct-2, Cele\mct-5, Cele\mct-4, Cele\mct-3" Xtro\slc16a9 "Mmus\Slc16a12, Mmus\Slc16a9, Mmus\Slc16a14, Mmus\Slc16a4, Mmus\Slc16a11, Mmus\Slc16a6, Mmus\Slc16a13" "Hsap\SLC16A13, Hsap\SLC16A9, Hsap\SLC16A11, Hsap\SLC16A4, Hsap\SLC16A14, Hsap\SLC16A6, Hsap\SLC16A12, Hsap\SLC16A8" viable FBgn0003532 stmC stambha C http://flybase.org/reports/FBgn0003532 - gene - - - "stm-C, stmC" - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,recessive,heat sensitive" FBgn0005507 l(2)24EFe lethal (2) 24EFe http://flybase.org/reports/FBgn0005507 - gene - - - "l(2)Gr.V, l(2)24EFe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010055 JmX Ju myoX http://flybase.org/reports/FBgn0010055 - gene - - - "Jm X, X, JmX" - - 11-Aug-17 DroID_v2017_08 - - - - - - long lived FBgn0013933 E(Pc)17B E(Pc)17B http://flybase.org/reports/FBgn0013933 - gene - - - "E(Pc)14B, E(Pc)17B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058418 CG40418 - http://flybase.org/reports/FBgn0058418 protein_coding_gene - - - CG40418 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053452 5SrRNA:CR33452 5SrRNA:CR33452 http://flybase.org/reports/FBgn0053452 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33452, 5SrRNA:CR33452" - CR33452 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035929 CG13311 - http://flybase.org/reports/FBgn0035929 protein_coding_gene - - - "BcDNA:RE29808, CG13311" - CG13311 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267064 CR45508 - http://flybase.org/reports/FBgn0267064 non_protein_coding_gene - - - CR45508 - CR45508 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083290 E(smoDN)2042 Enhancer of smoDN 2042 http://flybase.org/reports/FBgn0083290 gene - - - E(smoDN)2042 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038621 CG10864 - http://flybase.org/reports/FBgn0038621 protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" CG10864 "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG10864 11-Aug-17 DroID_v2017_08 "Drer\kcnk5b, Drer\kcnk10b, Drer\kcnk10a, Drer\kcnk5a, Drer\kcnk1a, Drer\kcnk6, Drer\kcnk7, Drer\kcnk18, Drer\kcnk2a, Drer\kcnk1b" Scer\TOK1 "Cele\twk-24, Cele\twk-48, Cele\twk-39, Cele\twk-28" "Xtro\LOC100486031, Xtro\kcnk1, Xtro\kcnk4, Xtro\kcnk16, Xtro\kcnk5, Xtro\kcnk6, Xtro\kcnk2, Xtro\kcnk7, Xtro\kcnk18, Xtro\kcnk10" "Mmus\Kcnk10, Mmus\Kcnk6, Mmus\Kcnk12, Mmus\Kcnk18, Mmus\Kcnk5, Mmus\Kcnk7, Mmus\Kcnk16, Mmus\Kcnk4, Mmus\Kcnk1, Mmus\Kcnk2" "Hsap\KCNK4, Hsap\KCNK18, Hsap\KCNK5, Hsap\KCNK7, Hsap\KCNK2, Hsap\KCNK10, Hsap\KCNK12, Hsap\KCNK16, Hsap\KCNK17, Hsap\KCNK6, Hsap\KCNK1" viable FBgn0264957 CR44126 - http://flybase.org/reports/FBgn0264957 non_protein_coding_gene - - - "lincRNA.251, CR44126" - CR44126 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265930 CR44719 - http://flybase.org/reports/FBgn0265930 non_protein_coding_gene - - - CR44719 - CR44719 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267553 CR45893 - http://flybase.org/reports/FBgn0267553 non_protein_coding_gene - - - CR45893 - CR45893 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267522 28SrRNA-Psi:CR45862 28S ribosomal RNA pseudogene:CR45862 http://flybase.org/reports/FBgn0267522 pseudogene_attribute - - - "28SrRNA-Psi:CR45862, CR45862" - CR45862 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259328 C109 - http://flybase.org/reports/FBgn0259328 gene - - - C109 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0263451 CR43474 - http://flybase.org/reports/FBgn0263451 non_protein_coding_gene - - - CR43474 - CR43474 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037753 CG12947 - http://flybase.org/reports/FBgn0037753 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12947 - CG12947 11-Aug-17 DroID_v2017_08 - - - - Mmus\Wfdc8 Hsap\WFDC8 viable FBgn0267755 CR46086 - http://flybase.org/reports/FBgn0267755 non_protein_coding_gene - - - CR46086 - CR46086 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002038 l(2)37Db lethal (2) 37Db http://flybase.org/reports/FBgn0002038 - gene - - - "E19, l(2)E19, l(2)37Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266823 CR45285 - http://flybase.org/reports/FBgn0266823 non_protein_coding_gene - - - CR45285 - CR45285 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017373 l(2)C103 lethal (2) C103 http://flybase.org/reports/FBgn0017373 - gene - - - "C103, l(2)C103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0010556 l(2)03788 lethal (2) 03788 http://flybase.org/reports/FBgn0010556 - gene - - - l(2)03788 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0005311 ms(2)73d male sterile (2) 73d http://flybase.org/reports/FBgn0005311 - gene - - - ms(2)73d - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" spermatid FBgn0002019 l(2)37Ac lethal (2) 37Ac http://flybase.org/reports/FBgn0002019 - gene - - - "37Ac, Ac, l(2)E145, l(2)37Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259761 dolly-2 double loops of the Y 2 http://flybase.org/reports/FBgn0259761 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "142-046, dolly-2, ms(3)142-46" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male sterile" "Y chromosome loop,spermatozoon" FBgn0011084 l(1)Q42 lethal (1) Q42 http://flybase.org/reports/FBgn0011084 FBgn0010210 gene - - - l(1)Q42 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038504 Sur-8 Sur-8 http://flybase.org/reports/FBgn0038504 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from biological aspect of ancestor with PANTHER:PTN002351899 protein phosphatase binding ; GO:0019903 | inferred from biological aspect of ancestor with PANTHER:PTN002351899 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D protein phosphatase type 1 complex ; GO:0000164 | inferred from biological aspect of ancestor with PANTHER:PTN001504428 "Sur8, SUR-8, CT17146, CG5407, Sur-8" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5" CG5407 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-106h11.1, Drer\shoc2" Scer\CYR1 "Cele\F43C1.1, Cele\ZK546.2, Cele\soc-2" Xtro\shoc2 "Mmus\Lrrd1, Mmus\Phlpp2, Mmus\Shoc2, Mmus\Phlpp1" "Hsap\PHLPP2, Hsap\SHOC2, Hsap\PHLPP1" viable FBgn0085193 CG34164 - http://flybase.org/reports/FBgn0085193 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34164 - CG34164 11-Aug-17 DroID_v2017_08 "Drer\rpl7l1, Drer\rpl7" "Scer\RLP7, Scer\RPL7B, Scer\RPL7A" - Xtro\rpl7 "Mmus\Npsr1, Mmus\Rpl7, Mmus\Rpl7l1" "Hsap\NPSR1, Hsap\RPL7L1, Hsap\RPL7" FBgn0005751 l(1)TK305 lethal (1) TK305 http://flybase.org/reports/FBgn0005751 - gene - - - "l305, l(1)TK305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086907 Cyt-c-d Cytochrome c distal http://flybase.org/reports/FBgn0086907 protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR002327, InterPro:IPR009056 electron carrier activity ; GO:0009055 | inferred from direct assay" "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000238899 sperm individualization ; GO:0007291 | inferred from mutant phenotype regulation of compound eye retinal cell programmed cell death ; GO:0046669 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000238899 oxidative phosphorylation ; GO:0006119 | inferred from sequence or structural similarity with SGD:S000003809" mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with SGD:S000003809 mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN000238899 "CG13263, cyt-c-d, cytochrome c, bln, Cytc, bs30f07.y1, cyt.c, DC3, CytC1, pDMc02, CytC-1, Cyt-c1, ms(2)04445, Cyt-c-d, Cytc-d, dc3, cyt c-d, cyt c, Cyt c, CytC, Cyt C, CYC, cyt.c-d" "IPR002327:Cytochrome c, class IA/ IB, IPR009056:Cytochrome c-like domain" CG13263 11-Aug-17 DroID_v2017_08 Drer\cycsb "Scer\CYC7, Scer\CYC1" "Cele\cyc-2.2, Cele\cyc-2.1" "Xtro\cyct, Xtro\cycs" "Mmus\Cycs, Mmus\Cyct" Hsap\CYCS " adult stage , larval stage--adult stage " " adult abdomen

, adult thorax

, adult head

" FBgn0002722 m(Est-6) modifier of Esterase 6 http://flybase.org/reports/FBgn0002722 - gene - - - "m-est, M-est, m(Est-6), m(Est6)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036534 DCP2 Decapping protein 2 http://flybase.org/reports/FBgn0036534 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR007722 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR007722 m7G(5')pppN diphosphatase activity ; GO:0050072 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VKK1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI2 "gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | NOT inferred from mutant phenotype regulation of cytoplasmic mRNA processing body assembly ; GO:0010603 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from mutant phenotype deadenylation-dependent decapping of nuclear-transcribed mRNA ; GO:0000290 | inferred from direct assay" cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "LD07107, BEST:LD07107, dDcp2, DCP2, CG6169, DCp2p, dcp2, dDcp, dDCP2, Dcp2" "IPR000086:NUDIX hydrolase domain, IPR007722:mRNA decapping protein 2, Box A domain, IPR015797:NUDIX hydrolase domain-like, IPR020084:NUDIX hydrolase, conserved site" CG6169 11-Aug-17 DroID_v2017_08 Drer\dcp2 Scer\DCP2 Cele\dcap-2 Xtro\dcp2 Mmus\Dcp2 Hsap\DCP2 "lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,lethal" cytoplasmic mRNA processing body | germline clone DRSC10597 EK -0.508309891 -0.117026778 -2.84195425 -3.90546502 2.911549358 2.172683374 FBgn0032731 Swip-1 Swiprosin-1 http://flybase.org/reports/FBgn0032731 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 mesoderm development ; GO:0007498 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from direct assay muscle tendon junction ; GO:0005927 | inferred from direct assay "CG10641, Swip-1, DSwip-1, EFhd2, efhd2, efhd" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG10641 11-Aug-17 DroID_v2017_08 "Drer\efhd2, Drer\efhd1" - Cele\efhd-1 "Xtro\efhd2, Xtro\efhd1" "Mmus\Efhd2, Mmus\Efhd1" "Hsap\EFHD2, Hsap\EFHD1" "visible,partially lethal - majority die,some die during pharate adult stage,viable,fertile" mesothoracic tergum FBgn0011165 l(1)DM-2 lethal (1) DM-2 http://flybase.org/reports/FBgn0011165 FBgn0010204 gene - - - l(1)DM-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024222 IKKbeta I-kappaB kinase beta http://flybase.org/reports/FBgn0024222 "FBgn0028725, FBgn0028726, FBgn0029099, FBgn0029160" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9GYV5 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity IkappaB kinase activity ; GO:0008384 | inferred from direct assay IkappaB kinase activity ; GO:0008384 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000540281 protein kinase activity ; GO:0004672 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q03017 regulation of innate immune response ; GO:0045088 | inferred from mutant phenotype positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype positive regulation of NF-kappaB transcription factor activity ; GO:0051092 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from direct assay positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | non-traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement protein catabolic process ; GO:0030163 | inferred from direct assay I-kappaB phosphorylation ; GO:0007252 | inferred from direct assay peptidyl-serine phosphorylation ; GO:0018105 | inferred from direct assay antibacterial humoral response ; GO:0019731 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 anatomical structure morphogenesis ; GO:0009653 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 defense response to virus ; GO:0051607 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype tumor necrosis factor-mediated signaling pathway ; GO:0033209 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype IkappaB kinase complex ; GO:0008385 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 cytoplasm ; GO:0005737 | inferred from direct assay "ird, dIKK-beta, IKK, IKK-beta, dIKK, IKKB, DmIKKb, DmIkkbeta, dmIKKbeta, ird5/DmIkk[beta], DmIKKbeta, CG4201, DmIKK, Dmikkbeta, DmIKKBeta, dLak, Ird-5, Ik, ikk, LRK, DLAK, DIK, anon-89Bd, Lak, IK, dIKKbeta, IKKbeta, IKKb, Ird5, ird5, IRD-5, IRD5, Ikkbeta, Dmikkb, ird-5, Ikkb, ird[5]" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG4201 11-Aug-17 DroID_v2017_08 "Drer\chuk, Drer\ikbke, Drer\ikbkb, Drer\tbk1" - - "Xtro\LOC101732839, Xtro\chuk, Xtro\ikbkb, Xtro\tbk1" "Mmus\Ikbke, Mmus\Tbk1, Mmus\Ikbkb, Mmus\Chuk" "Hsap\IKBKB, Hsap\IKBKE, Hsap\CHUK, Hsap\ERLIN1, Hsap\TBK1" embryonic stage -- adult stage "immune response defective,viable,fertile,recessive,partially lethal - majority die" FBgn0000981 fs(2)HO294 female sterile (2) HO294 http://flybase.org/reports/FBgn0000981 - gene - - - "fs(2)294A, fs(2)HO294" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005083 fs(2)OW807 female sterile (2) OW807 http://flybase.org/reports/FBgn0005083 - gene - - - fs(2)OW807 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005057 fs(2)OW103 female sterile (2) OW103 http://flybase.org/reports/FBgn0005057 - gene - - - fs(2)OW103 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086519 Cpr47Eg Cuticular protein 47Eg http://flybase.org/reports/FBgn0086519 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Lcp2a, BcDNA:RE09259, CG9070, Cpr47Eg, Cpr47eg" "IPR000618:Insect cuticle protein, IPR031305:Casein alpha/beta, conserved site" CG9070 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0033442 CG1690 - http://flybase.org/reports/FBgn0033442 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG1690 - CG1690 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC06636 I 1.675317898 1.408913124 -0.268452981 1.010431759 0.164064832 0.337068218 FBgn0043852 vizhichai vizhichai http://flybase.org/reports/FBgn0043852 gene - - - vizhichai - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031115 CG11710 - http://flybase.org/reports/FBgn0031115 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR009349 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000311349 "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN000311349" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000311349 CG11710 "IPR009349:Zinc finger, C2HC5-type, IPR007374:ASCH domain, IPR015947:PUA-like domain" CG11710 11-Aug-17 DroID_v2017_08 Drer\trip4 Scer\YKR023W Cele\asc-1 Xtro\trip4 Mmus\Trip4 Hsap\TRIP4 "viable,fertile" FBgn0066304 Rpp20 Rpp20 http://flybase.org/reports/FBgn0066304 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002775 protein binding ; GO:0005515 | inferred from physical interaction with SA-2 ribonuclease P activity ; GO:0004526 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001433784 "RNA phosphodiester bond hydrolysis, endonucleolytic ; GO:0090502 | inferred from biological aspect of ancestor with PANTHER:PTN001433784 tRNA processing ; GO:0008033 | inferred from biological aspect of ancestor with PANTHER:PTN001433784" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mitochondrial ribonuclease P complex ; GO:0030678 | non-traceable author statement ribonuclease P complex ; GO:0030677 | non-traceable author statement "dRpp20, CG12533, CG32530, CG33931, BcDNA:RE70209, CG32530-ORFA, Rpp20" "IPR002775:DNA/RNA-binding protein Alba-like, IPR014612:Ribonucleases P/MRP protein subunit Rpp20" CG33931 11-Aug-17 DroID_v2017_08 Drer\pop7 - Cele\Y62E10A.2 - Mmus\Pop7 Hsap\POP7 DRSC19467 I -0.252305484 1.617374953 0.031056917 -0.890437835 -0.378523315 -0.463887417 FBgn0031834 CG13766 - http://flybase.org/reports/FBgn0031834 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG13766, FBXO16" "IPR032675:Leucine-rich repeat domain, L domain-like" CG13766 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265905 CR44694 - http://flybase.org/reports/FBgn0265905 non_protein_coding_gene - - - CR44694 - CR44694 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264324 spg sponge http://flybase.org/reports/FBgn0264324 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with mbc small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR026791 central nervous system development ; GO:0007417 | inferred from mutant phenotype R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype activation of GTPase activity ; GO:0090630 | inferred from sequence or structural similarity with mbc cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG31048, spg, mat(3)6, mat3(6), CG14530, CG11754, Dm Dock4, Spg" "IPR027357:DHR-2 domain, IPR027007:DHR-1 domain, IPR026791:Dedicator of cytokinesis, IPR031057:DOCK1 homologue, IPR011989:Armadillo-like helical, IPR001452:SH3 domain, IPR010703:Dedicator of cytokinesis, C-terminal, IPR032376:Dedicator of cytokinesis, N-terminal domain" CG31048 11-Aug-17 DroID_v2017_08 "Drer\dock5, Drer\dock4b, Drer\dock1, Drer\dock3, Drer\si:dkey-81e3.1" Scer\DCK1 Cele\ced-5 "Xtro\dock2, Xtro\dock4, Xtro\dock1, Xtro\dock3" "Mmus\Dock4, Mmus\Dock5, Mmus\Dock3, Mmus\Dock1, Mmus\Dock2" "Hsap\DOCK2, Hsap\DOCK3, Hsap\DOCK1, Hsap\DOCK4, Hsap\DOCK5" DRSC14373 K 0.514689583 -0.029580176 -0.674992531 -0.268635216 1.278231026 1.870291905 FBgn0034931 CG2812 - http://flybase.org/reports/FBgn0034931 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2812 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain" CG2812 11-Aug-17 DroID_v2017_08 "Drer\wdr47a, Drer\wdr47b" Scer\STE4 Cele\nmtn-1 Xtro\wdr47 Mmus\Wdr47 Hsap\WDR47 DRSC04319 E 0.110972793 -0.660044717 1.312456419 -2.172168795 -0.325159383 0.517171597 FBgn0053493 CG33493 - http://flybase.org/reports/FBgn0053493 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6463, CG33493" - CG33493 11-Aug-17 DroID_v2017_08 Drer\ndufa5 - - Xtro\ndufa5 Mmus\Ndufa5 Hsap\NDUFA5 DRSC10642 K 0.787123651 0.548234082 -0.009949425 0.956559679 0.383486706 1.65407862 FBgn0039067 wda will decrease acetylation http://flybase.org/reports/FBgn0039067 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype histone H3-K9 acetylation ; GO:0043970 | inferred from mutant phenotype SAGA complex ; GO:0000124 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Wda, wda, CG4448, WFA, WDA" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR007582:TFIID subunit TAF5, NTD2 domain" CG4448 11-Aug-17 DroID_v2017_08 "Drer\egln1a, Drer\taf5, Drer\taf5l, Drer\egln1b, Drer\egln3, Drer\egln2" Scer\TAF5 Cele\taf-5 "Xtro\egln3, Xtro\egln2, Xtro\egln1, Xtro\taf5, Xtro\taf5l" "Mmus\Egln1, Mmus\Taf5, Mmus\Egln2, Mmus\Taf5l, Mmus\Wdr38, Mmus\Egln3" "Hsap\EGLN1, Hsap\EGLN2, Hsap\EGLN3, Hsap\TAF5L, Hsap\TAF5" "lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,visible" trichogen cell DRSC15579 IE 1.694845856 0.932294183 0.097777079 1.661479182 0.21828886 0.372780212 FBgn0050326 tRNA:Val-AAC-2-2 transfer RNA:Valine-AAC 2-2 http://flybase.org/reports/FBgn0050326 tRNA_gene GUU codon-amino acid adaptor activity ; GO:0033449 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033449 cytosol ; GO:0005829 | inferred by curator from GO:0033449 "CR30326, AE002787.trna52-ValAAC, valine tRNA, tRNA[Val][[4]], tRNA:val4:56D, tRNA:V4:56D, tRNA:V:AAC:AE002787-b, CR30226, tRNA[Val-AAC], chr2R.trna35-ValAAC, tRNA:Val-AAC-2-2, tRNA:CR30326, tRNA-Val-AAC-2-2, GUU" - CR30326 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058096 CG40096 - http://flybase.org/reports/FBgn0058096 protein_coding_gene - - - CG40096 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030100 CG12106 - http://flybase.org/reports/FBgn0030100 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GH03263, CG12106" IPR017920:COMM domain CG12106 11-Aug-17 DroID_v2017_08 Drer\commd3 - Cele\B0281.4 - Mmus\Commd3 Hsap\COMMD3 "viable,planar polarity defective" FBgn0015417 l(1)16ACa lethal (1) 16ACa http://flybase.org/reports/FBgn0015417 - gene - - - l(1)16ACa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014208 l(1)9-38-1 lethal (1) 9-38-1 http://flybase.org/reports/FBgn0014208 - gene - - - "l(1)14Cc, l(1)9-38-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260363 GSd248 - http://flybase.org/reports/FBgn0260363 gene - - - GSd248 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0020290 l(2)M167 lethal (2) M167 http://flybase.org/reports/FBgn0020290 - gene - - - l(2)M167 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,recessive" FBgn0266808 CR45270 - http://flybase.org/reports/FBgn0266808 non_protein_coding_gene - - - CR45270 - CR45270 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051333 tRNA:Thr-CGT-1-3 transfer RNA:Threonine-CGT 1-3 http://flybase.org/reports/FBgn0051333 tRNA_gene ACG codon-amino acid adaptor activity ; GO:0033440 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033440 cytosol ; GO:0005829 | inferred by curator from GO:0033440 "AE002708.trna25-ThrCGT, tRNA[Thr][[4]], tRNA[Thr][[3]], tRNA:T3:93AB, tRNA:thr4:93A, tRNA:T4:93A, tRNA:T:CGT:AE002708-c, CR31333, tRNA[[Thr]], chr3R.trna31-ThrCGT, tRNA-Thr-CGT-1-3, tRNA:Thr-CGT-1-3, tRNA:CR31333, ACG" - CR31333 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017610 Grt Glucose repressible transcripts http://flybase.org/reports/FBgn0017610 - gene - - - Grt - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040646 CG14580 - http://flybase.org/reports/FBgn0040646 protein_coding_gene - - - CG14580 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024237 fl338 fl338 http://flybase.org/reports/FBgn0024237 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available fl338 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female,dosage compensation defective" FBgn0259187 Ir60d Ionotropic receptor 60d http://flybase.org/reports/FBgn0259187 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG13582, DmelIR60d, CG42291, Ir60d, IR60d" - CG42291 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005097 Fs(2)Y12 Female sterile (2) Y12 http://flybase.org/reports/FBgn0005097 - gene - - - "fs(2)Y12, Fs(2)Y12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,semidominant" egg FBgn0261880 Taf Tripped-and-fell http://flybase.org/reports/FBgn0261880 gene - - - Taf - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,dominant,heat sensitive,neurophysiology defective,viable" FBgn0265189 sud1 sudestada1 http://flybase.org/reports/FBgn0265189 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620, InterPro:IPR019601 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620, InterPro:IPR019601 L-ascorbic acid binding ; GO:0031418 | inferred from sequence model with InterPro:IPR006620,InterPro:IPR019601 peptidyl-proline dioxygenase activity ; GO:0031543 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR019601 regulation of translation ; GO:0006417 | inferred from mutant phenotype oxidation-reduction process ; GO:0055114 | inferred from sequence model with InterPro:IPR005123,InterPro:IPR006620,InterPro:IPR019601 regulation of translational termination ; GO:0006449 | inferred from biological aspect of ancestor with PANTHER:PTN000251752 peptidyl-proline hydroxylation ; GO:0019511 | inferred from mutant phenotype protein hydroxylation ; GO:0018126 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG44254, CG18761, CG31120, sud1" "IPR019601:Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG44254 11-Aug-17 DroID_v2017_08 Drer\ogfod1 "Scer\TPA1, Scer\GPI17" "Cele\hpo-5, Cele\C17G10.1" Xtro\ogfod1 "Mmus\Pigs, Mmus\Ogfod1" "Hsap\OGFOD1, Hsap\PIGS" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0065080 snoRNA:Me18S-A1374 - http://flybase.org/reports/FBgn0065080 snoRNA_gene - - - "Dm-122, snoR122, CR33634, snoRNA:Me18S-A1374, Me18S-A1374(snoR122), snoRNA:122" - CR33634 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011074 l(1)Q27 lethal (1) Q27 http://flybase.org/reports/FBgn0011074 FBgn0010210 gene - - - l(1)Q27 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065371 l(2)SH1701 lethal (2) SH1701 http://flybase.org/reports/FBgn0065371 gene - - - "l(2)SH1701, l(2)SH2 1701" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039227 polybromo polybromo http://flybase.org/reports/FBgn0039227 protein_coding_gene chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR001025 "vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype negative regulation of chromatin silencing ; GO:0031936 | inferred from genetic interaction with Pc, Bap170 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from genetic interaction with Bap170 inferred from genetic interaction with Bap170, e(y)3 inferred from genetic interaction with Bap170, e(y)3 eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype" polytene chromosome ; GO:0005700 | inferred from direct assay PBAF complex ; GO:0070604 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay "Polybromo, CG11375, baf180, BAF180, anon-WO0140519.158, polybromo, bap180, PB, Pb, Bap180, POLYBROMO" "IPR018359:Bromodomain, conserved site, IPR001025:Bromo adjacent homology (BAH) domain, IPR001487:Bromodomain, IPR009071:High mobility group box domain" CG11375 11-Aug-17 DroID_v2017_08 "Drer\pbrm1l, Drer\pbrm1" "Scer\RSC2, Scer\RSC1, Scer\RSC4" Cele\pbrm-1 Xtro\pbrm1 Mmus\Pbrm1 Hsap\PBRM1 "viable,fertile,visible,dominant,female sterile,homeotic,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,enhancer of variegation" "wing vein,ectopic,vitelline membrane,chorion,adult abdominal segment 6,adult abdominal segment 5" FBgn0029791 CG4096 - http://flybase.org/reports/FBgn0029791 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001590, InterPro:IPR002870, InterPro:IPR006586, InterPro:IPR010294 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002870, InterPro:IPR013273" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001590, InterPro:IPR002870 negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Ras85D inferred from genetic interaction with vn, Krn inferred from genetic interaction with spi, Krn" proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR013273 "CT13580, CG4096" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR001590:Peptidase M12B, ADAM/reprolysin, IPR002870:Peptidase M12B, propeptide, IPR010294:ADAM-TS Spacer 1, IPR013273:Peptidase M12B, ADAM-TS, IPR024079:Metallopeptidase, catalytic domain, IPR006586:ADAM, cysteine-rich" CG4096 11-Aug-17 DroID_v2017_08 "Drer\adamts17, Drer\thsd7bb, Drer\adamts18, Drer\adamts8a, Drer\adamtsl3, Drer\spint2, Drer\col6a3, Drer\adamtsl5, Drer\paplna, Drer\adamts10, Drer\adamts12, Drer\adamts7, Drer\adamts1, Drer\adamtsl2, Drer\paplnb, Drer\adamtsl7, Drer\adamts2, Drer\tfpia, Drer\tfpi2, Drer\LOC568792, Drer\adamts15a, Drer\adamts13, Drer\LOC100002059, Drer\adamts6" - "Cele\Y8A9A.2, Cele\T02G6.11, Cele\mig-6, Cele\T19D2.1, Cele\gon-1, Cele\adt-2, Cele\adt-1" "Xtro\adamts13, Xtro\adamts15, Xtro\adamtsl4, Xtro\adamts14, Xtro\adamts6, Xtro\adamts9, Xtro\adamts3, Xtro\adamts16, Xtro\adamts18, Xtro\adamts20, Xtro\adamts12, Xtro\spint2, Xtro\papln, Xtro\adamts10, Xtro\adamts7, Xtro\tfpi2, Xtro\adamts2, Xtro\adamts17" "Mmus\Adamts19, Mmus\Adamts20, Mmus\Adamts18, Mmus\Adamts3, Mmus\Adamts15, Mmus\Col6a3, Mmus\Adamts13, Mmus\Adamts9, Mmus\Adamts17, Mmus\Adamts12, Mmus\Adamts16, Mmus\Adamts8, Mmus\Adamts10, Mmus\Tfpi, Mmus\Sspo, Mmus\Thsd7a, Mmus\Adamts14, Mmus\Thsd4, Mmus\Adamts6, Mmus\Adamtsl5, Mmus\Adamts2, Mmus\Adamts1, Mmus\Adamtsl4, Mmus\Adamts4, Mmus\Adamts7, Mmus\Adamtsl1, Mmus\Papln, Mmus\Tfpi2" "Hsap\ADAMTS12, Hsap\SPINT3, Hsap\PAPLN, Hsap\ADAMTS9, Hsap\ADAMTS18, Hsap\ADAMTS7, Hsap\ADAMTS14, Hsap\ADAMTS10, Hsap\ADAMTS6, Hsap\ADAMTS3, Hsap\ADAMTSL5, Hsap\ADAMTSL1, Hsap\TFPI2, Hsap\COL6A3, Hsap\ADAMTS2, Hsap\ADAMTS13, Hsap\TFPI, Hsap\ADAMTS20, Hsap\ADAMTS4, Hsap\THSD4, Hsap\ADAMTSL4, Hsap\ADAMTS1, Hsap\ADAMTS19, Hsap\THSD7B, Hsap\ADAMTS15, Hsap\ADAMTS17, Hsap\ADAMTS16, Hsap\ADAMTS8" "viable,fertile,visible" "wing vein,ectopic,wing" FBgn0039355 CG4730 - http://flybase.org/reports/FBgn0039355 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG4730 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG4730 11-Aug-17 DroID_v2017_08 "Drer\klf12b, Drer\klf12a, Drer\vezf1a, Drer\znf281a, Drer\si:ch211-166g5.4, Drer\klf3, Drer\LOC100535691, Drer\znf740a, Drer\si:dkey-262g12.7, Drer\znf281b, Drer\znf740b, Drer\LOC101882721, Drer\vezf1b" Scer\AZF1 "Cele\eor-1, Cele\snai-1, Cele\ZK686.5, Cele\ztf-6" Xtro\zfp1 "Mmus\Zfp1, Mmus\Klf8, Mmus\Maz, Mmus\Zfp637, Mmus\Klf12, Mmus\Zfp362, Mmus\Klf3, Mmus\Vezf1, Mmus\Zfp281" "Hsap\ZNF362, Hsap\KLF8, Hsap\KLF3, Hsap\ZFP1, Hsap\MAZ, Hsap\ZNF32, Hsap\ZNF281, Hsap\ZNF740, Hsap\VEZF1, Hsap\KLF12" "viable,fertile" FBgn0044051 Ilp1 Insulin-like peptide 1 http://flybase.org/reports/FBgn0044051 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from biological aspect of ancestor with PANTHER:PTN001414741 insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 regulation of glucose metabolic process ; GO:0010906 | inferred from biological aspect of ancestor with PANTHER:PTN001414741 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "dilp, DILP, dilp-1, Dilp, dilp1, Dilp 1, DILP1, CG14173, Ilp1, Ilp, Dilp-1, Dilp1, Ilp-1, ilp1, DILP-1, dILP1" "IPR016179:Insulin-like, IPR022352:Insulin family, IPR022353:Insulin, conserved site" CG14173 11-Aug-17 DroID_v2017_08 - - Cele\ins-1 - - - "viable,small body" FBgn0267318 CR45754 - http://flybase.org/reports/FBgn0267318 non_protein_coding_gene - - - CR45754 - CR45754 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066132 E(sda)A E(sda)A http://flybase.org/reports/FBgn0066132 gene molecular_function ; GO:0003674 | no biological data available mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E(sda)A, Line A" - - 11-Aug-17 DroID_v2017_08 - - - - - - bang sensitive FBgn0058116 CG40116 - http://flybase.org/reports/FBgn0058116 protein_coding_gene - - - CG40116 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052254 CG32254 - http://flybase.org/reports/FBgn0052254 protein_coding_gene - - - "BcDNA:RH01388, CG32254" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21905 K 0.77029418 -0.079294308 -0.352191149 -0.541997711 1.980851792 0.120688902 FBgn0000433 depl depressed-like http://flybase.org/reports/FBgn0000433 - gene - - - "dep[r], depl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority live,body color defective" "wing,macrochaeta" FBgn0260299 GSd498 - http://flybase.org/reports/FBgn0260299 gene - - - GSd498 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266023 CR44788 - http://flybase.org/reports/FBgn0266023 non_protein_coding_gene - - - "CR44788, lincRNA.12" - CR44788 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010865 l(3)05408 lethal (3) 05408 http://flybase.org/reports/FBgn0010865 FBgn0011308 gene - - - "l(3)j1B3, l(3)05408" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040394 CG16903 - http://flybase.org/reports/FBgn0040394 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR015429 cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of phosphorylation of RNA polymerase II C-terminal domain ; GO:1901409 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 "EG:67A9.2, anon-WO03040301.211, CG16903" "IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like, IPR015429:Cyclin L/T, IPR004367:Cyclin, C-terminal domain" CG16903 11-Aug-17 DroID_v2017_08 "Drer\ccnl1b, Drer\ccnl1a" "Scer\BUR2, Scer\SSN8" "Cele\cit-1.2, Cele\cyl-1" "Xtro\ccnl2, Xtro\ccnl1" "Mmus\Ccnl1, Mmus\Ccnl2" "Hsap\CCNL2, Hsap\CCNL1" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0065836 l(2)SH0336 lethal (2) SH0336 http://flybase.org/reports/FBgn0065836 gene - - - "l(2)SH0336, l(2)SH2 0336" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037232 Suv3 Suv3 helicase http://flybase.org/reports/FBgn0037232 protein_coding_gene DNA helicase activity ; GO:0003678 | inferred from sequence or structural similarity with UniProtKB:Q8IYB8 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q8IYB8 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN002281432 RNA catabolic process ; GO:0006401 | inferred from biological aspect of ancestor with PANTHER:PTN002281432 DNA duplex unwinding ; GO:0032508 | inferred from sequence or structural similarity with UniProtKB:Q8IYB8 mitochondrial mRNA polyadenylation ; GO:0097222 | inferred from mutant phenotype regulation of mitochondrial mRNA stability ; GO:0044528 | inferred from mutant phenotype positive regulation of mitochondrial translation ; GO:0070131 | inferred from mutant phenotype mitochondrial RNA processing ; GO:0000963 | inferred from mutant phenotype oxidative phosphorylation ; GO:0006119 | inferred from mutant phenotype respiratory electron transport chain ; GO:0022904 | inferred from mutant phenotype mitochondrial tRNA processing ; GO:0090646 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q8IYB8 mitochondrial degradosome ; GO:0045025 | inferred from biological aspect of ancestor with PANTHER:PTN000252978 "CG9791, Suv3, dmsuv3, SUV3" "IPR001650:Helicase, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022192:Mitochondrial degradasome RNA helicase subunit, C-terminal domain" CG9791 11-Aug-17 DroID_v2017_08 Drer\supv3l1 Scer\SUV3 Cele\C08F8.2 Xtro\supv3l1 Mmus\Supv3l1 Hsap\SUPV3L1 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC12335 K -0.201561247 -0.564395001 -1.280551535 0.37742834 1.946842975 0.058877952 FBgn0041245 Gr39b Gustatory receptor 39b http://flybase.org/reports/FBgn0041245 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr39D1, 39D1, 39D.1, CG31620, GR39D.1, Gr39b, GR39b" IPR013604:7TM chemoreceptor CG31620 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - viable DRSC01848 IK -1.956293302 1.418062416 0.49927517 -0.068433708 -1.969369262 -0.498308641 FBgn0028878 CG15269 - http://flybase.org/reports/FBgn0028878 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "BG:DS04929.3, DS04929.3, CG15269" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15269 11-Aug-17 DroID_v2017_08 "Drer\plagl2, Drer\plagx, Drer\zbtb41" Scer\AZF1 "Cele\Y48G8AL.10, Cele\blmp-1, Cele\Y55F3AM.14, Cele\M03D4.4, Cele\sdz-12, Cele\fezf-1, Cele\Y5F2A.4, Cele\row-1" Xtro\plag1 "Mmus\Plag1, Mmus\Plagl2, Mmus\Zfp273, Mmus\Zscan10, Mmus\Plagl1, Mmus\Zfp13, Mmus\Zfp276, Mmus\Zfp629, Mmus\Zfp384, Mmus\Zfp362" "Hsap\ZNF629, Hsap\ZNF613, Hsap\ZNF628, Hsap\ZNF652, Hsap\ZNF667, Hsap\ZNF232, Hsap\ZNF621, Hsap\ZNF276, Hsap\PLAGL2, Hsap\PLAGL1, Hsap\PLAG1, Hsap\PRDM16, Hsap\ZNF205" viable FBgn0034009 CG8155 - http://flybase.org/reports/FBgn0034009 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype autophagosome ; GO:0005776 | inferred from biological aspect of ancestor with PANTHER:PTN000538498 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG8155 IPR000195:Rab-GTPase-TBC domain CG8155 11-Aug-17 DroID_v2017_08 "Drer\tbc1d15, Drer\tbc1d17, Drer\tbc1d25, Drer\si:dkey-238d18.4" Scer\GYP7 - - "Mmus\Tbc1d25, Mmus\Tbc1d15, Mmus\Tbc1d21, Mmus\Tbc1d17" "Hsap\TBC1D21, Hsap\TBC1D15, Hsap\TBC1D17, Hsap\TBC1D25" "long lived,visible,partially lethal - majority die,some die during pupal stage,cell migration defective" "trichogen cell,mesothoracic tergum,border follicle cell" FBgn0033635 Prip Prip http://flybase.org/reports/FBgn0033635 protein_coding_gene channel activity ; GO:0015267 | inferred from sequence or structural similarity with Drip water channel activity ; GO:0015250 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 transmembrane transport ; GO:0055085 | inferred from sequence or structural similarity with Drip ion transmembrane transport ; GO:0034220 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Drip integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 "CG7777, Aqp7777, Prip" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR023271:Aquaporin-like" CG7777 11-Aug-17 DroID_v2017_08 "Drer\aqp1a.1, Drer\aqp8a.2, Drer\aqp3b, Drer\mipa, Drer\aqp1a.2, Drer\aqp8b, Drer\aqp4, Drer\aqp3a, Drer\mipb, Drer\si:dkey-30h22.11, Drer\aqp8a.1" "Scer\AQY2, Scer\YLL053C, Scer\YFL054C, Scer\AQY1" "Cele\aqp-4, Cele\aqp-7, Cele\aqp-6, Cele\aqp-2, Cele\aqp-8, Cele\aqp-5" "Xtro\mip, Xtro\LOC100216133, Xtro\aqp2, Xtro\fam188b, Xtro\aqp5, Xtro\LOC100489792, Xtro\aqp1, Xtro\aqp8" "Mmus\Aqp1, Mmus\Aqp2, Mmus\Aqp4, Mmus\Aqp3, Mmus\Aqp8, Mmus\Aqp5, Mmus\Aqp6, Mmus\Mip, Mmus\Aqp7, Mmus\Fam188b" "Hsap\MIP, Hsap\FAM188B2, Hsap\AQP3, Hsap\AQP6, Hsap\AQP5, Hsap\AQP7, Hsap\AQP9, Hsap\AQP1, Hsap\AQP4, Hsap\AQP8, Hsap\AQP2" viable FBgn0063393 sip sine prole http://flybase.org/reports/FBgn0063393 gene - cystoblast division ; GO:0007282 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype - sip - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "spermatozoon,spermatid,egg chamber,nurse cell,ovary,follicle cell" FBgn0265548 CR44398 - http://flybase.org/reports/FBgn0265548 non_protein_coding_gene - - - "CR44398, lincRNA.176" - CR44398 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267549 CR45889 - http://flybase.org/reports/FBgn0267549 non_protein_coding_gene - - - CR45889 - CR45889 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027836 Dgp-1 Dgp-1 http://flybase.org/reports/FBgn0027836 - protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG5729, Dgp-1" "IPR000795:Transcription factor, GTP-binding domain, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5729 11-Aug-17 DroID_v2017_08 "Drer\gtpbp1l, Drer\gtpbp2, Drer\gtpbp1" - "Cele\cgp-1, Cele\T04H1.2" "Xtro\gtpbp1, Xtro\gtpbp2" "Mmus\Gtpbp1, Mmus\Gtpbp2" "Hsap\GTPBP2, Hsap\GTPBP1" "viable,fertile,body color defective" mesothoracic tergum FBgn0033571 Rpb5 Rpb5 http://flybase.org/reports/FBgn0033571 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000783, InterPro:IPR005571, InterPro:IPR020609 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000056681 RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000056681 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9192 inferred from sequence or structural similarity with SGD:S000000358 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000056681" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9192 inferred from sequence or structural similarity with SGD:S000000358 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9192 inferred from sequence or structural similarity with SGD:S000000358 DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from biological aspect of ancestor with PANTHER:PTN000056681 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN000056681 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000056681" "RPB5, CG11979, DmRPB5, Rpb5" "IPR000783:RNA polymerase, subunit H/Rpb5 C-terminal, IPR005571:RNA polymerase, Rpb5, N-terminal, IPR014381:DNA-directed RNA polymerase RPB5 subunit, eukaryote/virus, IPR020609:Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit, IPR020608:RNA polymerase, subunit H/Rpb5, conserved site" CG11979 11-Aug-17 DroID_v2017_08 "Drer\polr2ea, Drer\polr2eb" Scer\RPB5 Cele\rpb-5 Xtro\polr2e Mmus\Polr2e Hsap\POLR2E DRSC06100 IEK -0.798890607 1.895526195 -4.049868687 -0.928224466 1.34282151 4.602999553 FBgn0027324 l(1)G0041 lethal (1) G0041 http://flybase.org/reports/FBgn0027324 - gene - - - l(1)G0041 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,melanotic mass phenotype,recessive" melanotic mass FBgn0030536 CG11068 - http://flybase.org/reports/FBgn0030536 protein_coding_gene - - - CG11068 - CG11068 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013668 ms(3)neo4 ms(3)neo4 http://flybase.org/reports/FBgn0013668 - gene - - - ms(3)neo4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "semi-sterile,male sterile" FBgn0053099 CG33099 - http://flybase.org/reports/FBgn0053099 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005123 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 - "CG5340, CG33099" "IPR027443:Isopenicillin N synthase-like, IPR026992:Non-haem dioxygenase N-terminal domain, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG33099 11-Aug-17 DroID_v2017_08 Drer\si:dkey-10o6.2 - - - - - viable FBgn0058363 CG40363 - http://flybase.org/reports/FBgn0058363 protein_coding_gene - - - CG40363 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028980 tant tantalus http://flybase.org/reports/FBgn0028980 protein_coding_gene - sensory organ development ; GO:0007423 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG6586, tan, tant" IPR028149:Tantalus-like CG6586 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,fertile,recessive,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "interocellar bristle,eye,ommatidium,interommatidial bristle,supernumerary,macrochaeta,scutellar bristle,abdominal sternite bristle,ectopic,abdominal tergite & macrochaeta,abdominal tergite & macrochaeta | ectopic,wing vein L5,postvertical bristle,wing vein,sex comb,joint,tarsal segment,wing,wing margin,macrochaeta & thorax-537.4,ocellar bristle" FBgn0086397 BG02320 - http://flybase.org/reports/FBgn0086397 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02320 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0051260 CG31260 - http://flybase.org/reports/FBgn0051260 protein_coding_gene - - - CG31260 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262459 mir-34 mir-34 stem loop http://flybase.org/reports/FBgn0262459 miRNA_gene mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-34, mir-34, miR-34, 34, MIR-34, CR43033, Mir-34, CR33326, dme-miR-34, dme-miR-34-5p, miR-34-5p" - CR43033 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage--prepupal stage , adult stage " "viable,lethal,long lived,short lived,gravitaxis defective,conditional,heat stress response defective,neuroanatomy defective" "wing,adult brain,conditional" FBgn0035198 CG9133 - http://flybase.org/reports/FBgn0035198 protein_coding_gene - - - "bs29f09.y1, CG32332, BEST:GH19464, BEST:GH19274, anon-WO0140519.53, anon-WO0140519.145, CG9133, AT07490" - CG9133 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084058 l(3)82CDe lethal (3) 82CDe http://flybase.org/reports/FBgn0084058 gene - - - l(3)82CDe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0062567 Mod(var)E646 Mod(var)E646 http://flybase.org/reports/FBgn0062567 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E646, Mod(var)E646" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0002794 ms(1)1 male sterile (1) 1 http://flybase.org/reports/FBgn0002794 - gene - - - ms(1)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile,viable" "spermatid axoneme,spermatid" FBgn0028571 ren renegade http://flybase.org/reports/FBgn0028571 gene - - - ren - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263945 BG00528 - http://flybase.org/reports/FBgn0263945 gene - - - BG00528 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0025481 ms(3)85E male sterile (3) 85E http://flybase.org/reports/FBgn0025481 - gene - - - "ms(3)KM27, ms(3)85E" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0265691 CR44498 - http://flybase.org/reports/FBgn0265691 non_protein_coding_gene - - - CR44498 - CR44498 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002531 Lcp1 Larval cuticle protein 1 http://flybase.org/reports/FBgn0002531 - protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from direct assay larval chitin-based cuticle development ; GO:0008363 | inferred by curator from GO:0008010 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from sequence model "Lcp1, DMLCP1, L[[3]]CP1, LCP-1, 1, I, CP1, LCP1, CG11650, DmelLcp1, lcp1" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG11650 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " larval stage | late third instar larval stage , larval stage | third instar stage 2 " " organism

, integumentary system

" "electrophoretic variant,viable" FBgn0267588 CR45926 - http://flybase.org/reports/FBgn0267588 non_protein_coding_gene - - - "CR45926, Mgn3564" - CR45926 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065444 l(2)SH1445 lethal (2) SH1445 http://flybase.org/reports/FBgn0065444 gene - - - "l(2)SH1445, l(2)SH2 1445" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024182 waw waclaw http://flybase.org/reports/FBgn0024182 "FBgn0014083, FBgn0052527, FBtr0077200, FBpp0076899, FBtr0077201, FBpp0076900, FBtr0077202, FBpp0076901" protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR005225, InterPro:IPR006297" - - "tu2, CG32527, anon-19Fb, CG1410, waw" "IPR000640:Translation elongation factor EFG, V domain, IPR000795:Transcription factor, GTP-binding domain, IPR005225:Small GTP-binding protein domain, IPR006297:Elongation factor 4, IPR009022:Elongation factor G, III-V domain, IPR013842:GTP-binding protein LepA, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031157:Tr-type G domain, conserved site" CG1410 11-Aug-17 DroID_v2017_08 Drer\guf1 Scer\GUF1 Cele\ZK1236.1 Xtro\guf1 Mmus\Guf1 Hsap\GUF1 "viable,fertile" FBgn0037986 CG14736 - http://flybase.org/reports/FBgn0037986 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001972 CG14736 "IPR001107:Band 7 domain, IPR001972:Stomatin family" CG14736 11-Aug-17 DroID_v2017_08 "Drer\stoml1, Drer\stoml3a, Drer\stoml3b, Drer\zgc:112408, Drer\stom, Drer\nphs2" - "Cele\unc-1, Cele\unc-24, Cele\sto-6, Cele\sto-1, Cele\sto-5, Cele\sto-3, Cele\sto-2, Cele\mec-2, Cele\sto-4" "Xtro\stoml1, Xtro\stoml3" "Mmus\Nphs2, Mmus\Stom, Mmus\Stoml1, Mmus\Stoml3" "Hsap\NPHS2, Hsap\STOML1, Hsap\STOM, Hsap\STOML3" FBgn0260331 GSd113 - http://flybase.org/reports/FBgn0260331 gene - - - GSd113 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0045974 PdL45C1 PdL45C1 http://flybase.org/reports/FBgn0045974 gene - - - PdL45C1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266656 CR45163 - http://flybase.org/reports/FBgn0266656 non_protein_coding_gene - - - CR45163 - CR45163 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005016 dipp-7 defective in phototaxis plasticity 7 http://flybase.org/reports/FBgn0005016 - gene - - - dipp-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,visual behavior defective,phototaxis defective" photoreceptor FBgn0031436 ND-B17.2 NADH dehydrogenase (ubiquinone) B17.2 subunit http://flybase.org/reports/FBgn0031436 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR007763 electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR007763 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:Q9UI09 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:Q9UI09 response to oxidative stress ; GO:0006979 | inferred from biological aspect of ancestor with PANTHER:PTN000308146" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:Q9UI09 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000308146 "anon-EST:Posey62, BcDNA:GH12382, CG3214, B17.2, N7BM, ND-B17.2" IPR007763:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 CG3214 11-Aug-17 DroID_v2017_08 "Drer\ndufa12, Drer\ndufaf2" - Cele\Y94H6A.8 Xtro\ndufa12 "Mmus\Ndufaf2, Mmus\Ndufa12" "Hsap\NDUFA12, Hsap\NDUFAF2" "viable,visible" trichogen cell FBgn0260267 GSd318 - http://flybase.org/reports/FBgn0260267 gene - - - GSd318 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0005451 l(1)v231 lethal (1) v231 http://flybase.org/reports/FBgn0005451 - gene - - - "l(1)231, l(1)v231" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016882 l(2)39DEg lethal (2) 39DEg http://flybase.org/reports/FBgn0016882 - gene - - - "K213, l(2)39DEg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005088 fs(2)OW812 female sterile (2) OW812 http://flybase.org/reports/FBgn0005088 - gene - - - fs(2)OW812 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002300 l(3)81Fa lethal (3) 81Fa http://flybase.org/reports/FBgn0002300 - gene - - - "l(3)Rh1, l(3)81Fa, 81Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001149 GstD1 Glutathione S transferase D1 http://flybase.org/reports/FBgn0001149 FBgn0010045 protein_coding_gene DDT-dehydrochlorinase activity ; GO:0018833 | inferred from direct assay glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GST-1, GSTD1, DmGSTD1-1, CG10045, T5, DmGSTD1, gstD1, DmGST1, DmGST-1, Gst, GST1, gst-D1-1, GST, G-S-T, Gst1-1, GST1-1, GSt1-1, Gst1, DmGst1, GSTase, Gst1.1, GstD1, gstd1, GST-D1, gst-D, dmGSTD1, Gst-D1, D1, gstD, GstD" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG10045 11-Aug-17 DroID_v2017_08 "Drer\gstt2, Drer\mars, Drer\eef1e1, Drer\gstr, Drer\gstt1a, Drer\vars, Drer\eef1g, Drer\gstt1b" "Scer\YGR201C, Scer\GTT2, Scer\TEF4, Scer\URE2, Scer\CAM1, Scer\GTT1" - "Xtro\gstt1, Xtro\eef1e1, Xtro\eef1g" "Mmus\Eef1g, Mmus\Eef1e1, Mmus\Gstt1, Mmus\Gstt4, Mmus\Gstt2, Mmus\Gstt3, Mmus\Vars, Mmus\Mars" "Hsap\EEF1G, Hsap\MARS, Hsap\GSTT1, Hsap\GSTT2, Hsap\GSTT2B, Hsap\EEF1E1, Hsap\VARS" adult stage viable FBgn0031458 aph-1 anterior pharynx defective 1 http://flybase.org/reports/FBgn0031458 protein_coding_gene endopeptidase activity ; GO:0004175 | inferred from mutant phenotype positive regulation of catalytic activity ; GO:0043085 | inferred from electronic annotation with InterPro:IPR009294 Notch receptor processing ; GO:0007220 | inferred from biological aspect of ancestor with PANTHER:PTN000306733 protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000306732 Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with l(2)gd1 "late endosome ; GO:0005770 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | non-traceable author statement recycling endosome ; GO:0055037 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000306732 gamma-secretase complex ; GO:0070765 | inferred from physical interaction with nct, pen-2, Psn integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000306732" "Aph-1, Pen-1, Dm APH-1, pen-1, l(2)23Ag, l(2)23AB6, CG2855, aph-1, dAph-1, aph1, aph, Aph1" IPR009294:Gamma-secretase subunit Aph-1 CG2855 11-Aug-17 DroID_v2017_08 "Drer\aph1b, Drer\zgc:114200" - Cele\aph-1 Xtro\aph1a "Mmus\Aph1b, Mmus\Aph1c, Mmus\Aph1a" "Hsap\APH1A, Hsap\APH1B" "neuroanatomy defective,lethal,recessive,size defective,dominant,partially lethal,viable,visible" "embryonic/larval optic lobe,presumptive embryonic/larval nervous system,sensory mother cell & dorsal mesothoracic disc,wing,microchaeta,eye,macrochaeta,germline clone,maternal effect,tormogen cell" FBgn0041117 l(2)k09834 lethal (2) k09834 http://flybase.org/reports/FBgn0041117 gene - - - l(2)k09834 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030403 CG1824 - http://flybase.org/reports/FBgn0030403 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:Q9NUT2 transporter activity ; GO:0005215 | inferred from sequence or structural similarity with UniProtKB:Q9NUT2" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011527 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q9NUT2 CG1824 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG1824 11-Aug-17 DroID_v2017_08 "Drer\abcb8, Drer\si:dkey-57h18.2, Drer\abcb5, Drer\abcb11a, Drer\abcb10, Drer\abcb4, Drer\abcb3l1, Drer\tap1, Drer\abcb11b, Drer\abcb9" "Scer\MDL2, Scer\MDL1" "Cele\haf-1, Cele\pgp-14, Cele\pgp-9, Cele\haf-2, Cele\pgp-5, Cele\haf-4, Cele\haf-3, Cele\haf-7, Cele\pgp-7, Cele\pgp-8, Cele\pgp-6, Cele\pgp-1, Cele\haf-6, Cele\pgp-13, Cele\pgp-12, Cele\pgp-2, Cele\pgp-4, Cele\haf-8" "Xtro\tap2, Xtro\tap1, Xtro\abcb8, Xtro\LOC100494740" "Mmus\Tap2, Mmus\Abcb8, Mmus\Tap1, Mmus\Abcb1b, Mmus\Abcb10, Mmus\Abcb9, Mmus\Abcb1a, Mmus\Abcb4, Mmus\Abcb11, Mmus\Abcb5" "Hsap\ABCB5, Hsap\ABCB10, Hsap\TAP1, Hsap\TAP2, Hsap\ABCB11, Hsap\ABCB8, Hsap\ABCB9, Hsap\ABCB4" viable FBgn0086782 amn amnesiac http://flybase.org/reports/FBgn0086782 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity neuropeptide hormone activity ; GO:0005184 | traceable author statement neuropeptide hormone activity ; GO:0005184 | non-traceable author statement G-protein coupled receptor binding ; GO:0001664 | non-traceable author statement neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern courtship behavior ; GO:0007619 | traceable author statement cAMP-mediated signaling ; GO:0019933 | traceable author statement activation of adenylate cyclase activity ; GO:0007190 | traceable author statement memory ; GO:0007613 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype perineurial glial growth ; GO:0042066 | inferred from mutant phenotype olfactory learning ; GO:0008355 | traceable author statement long-term memory ; GO:0007616 | traceable author statement behavioral response to ethanol ; GO:0048149 | non-traceable author statement behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype learning ; GO:0007612 | NOT traceable author statement regulation of heart contraction ; GO:0008016 | non-traceable author statement cAMP-mediated signaling ; GO:0019933 | non-traceable author statement medium-term memory ; GO:0072375 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype cAMP biosynthetic process ; GO:0006171 | traceable author statement behavioral response to pain ; GO:0048266 | inferred from mutant phenotype anesthesia-resistant memory ; GO:0007615 | traceable author statement learning or memory ; GO:0007611 | non-traceable author statement thermosensory behavior ; GO:0040040 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | traceable author statement neuropeptide signaling pathway ; GO:0007218 | traceable author statement olfactory learning ; GO:0008355 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "amn, CG11937, EP(X)1442, Drm-amn, chpd, PACAP, PACAP-38, PACAP38, PACAP38-like, PACAP-like, Pacap38, Amn, Anm" - CG11937 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260070 2L1554 - http://flybase.org/reports/FBgn0260070 gene - - - 2L1554 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive,viable" "embryonic/larval tracheal system,somatic clone" FBgn0039075 CG4393 - http://flybase.org/reports/FBgn0039075 protein_coding_gene - - - CG4393 "IPR002110:Ankyrin repeat, IPR006020:PTB/PI domain, IPR011993:PH domain-like, IPR020683:Ankyrin repeat-containing domain, IPR013761:Sterile alpha motif/pointed domain, IPR001660:Sterile alpha motif domain, IPR033635:Ankyrin repeat and SAM domain-containing protein 1" CG4393 11-Aug-17 DroID_v2017_08 "Drer\anks1b, Drer\LOC564253, Drer\anks1ab" - Cele\C11E4.6 "Xtro\caskin2, Xtro\anks1a, Xtro\caskin1" "Mmus\Anks1b, Mmus\Caskin2, Mmus\Anks1" "Hsap\ANKS1B, Hsap\ANKS1A, Hsap\CASKIN2" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266202 CR44897 - http://flybase.org/reports/FBgn0266202 non_protein_coding_gene - - - CR44897 - CR44897 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032612 CG13282 - http://flybase.org/reports/FBgn0032612 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available CG13282 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG13282 11-Aug-17 DroID_v2017_08 "Drer\lpl, Drer\LOC100331214, Drer\lipca, Drer\lipia, Drer\sco1, Drer\lipg, Drer\pla1a, Drer\lipib, Drer\LOC101884800, Drer\sco2" - "Cele\sco-1, Cele\C41H7.6, Cele\C41H7.4, Cele\C08A9.6, Cele\Y51H4A.5, Cele\B0454.9, Cele\C06C3.8, Cele\T10B5.7, Cele\C40H1.2, Cele\C14E2.6" "Xtro\pnliprp3, Xtro\lpl, Xtro\lipg, Xtro\pnliprp2" "Mmus\Lipi, Mmus\Lpl, Mmus\Pnlip, Mmus\Sco2, Mmus\Liph, Mmus\Pla1a, Mmus\Pnliprp1, Mmus\Lipc, Mmus\Pnliprp2, Mmus\Lipg, Mmus\Sco1" "Hsap\PNLIP, Hsap\PNLIPRP1, Hsap\LIPI, Hsap\PNLIPRP3, Hsap\SCO2, Hsap\LIPH, Hsap\LIPC, Hsap\SCO1, Hsap\LIPG, Hsap\PLA1A, Hsap\PNLIPRP2, Hsap\LPL" viable FBgn0017410 ci::en ci::en http://flybase.org/reports/FBgn0017410 - engineered_fusion_gene - - - ci::en - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing vein L3,wing vein L4,gastric caecum primordium" FBgn0023141 WppB White prepupal locus B http://flybase.org/reports/FBgn0023141 - gene - - - "5, 2, WppB" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250899 zaa90g02 - http://flybase.org/reports/FBgn0250899 gene - - - "zaa90g02, zaa90g02y1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083058 snoRNA:Psi18S-1086 snoRNA:Psi18S-1086 http://flybase.org/reports/FBgn0083058 snoRNA_gene - - - "snoRNA:Psi18S-1086, psi18s-1086, Psi 18S-1086, CR34633" - CR34633 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061113 l(3)S005916b lethal (3) S005916b http://flybase.org/reports/FBgn0061113 gene - - - "0059/16, l(3)S005916b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal" FBgn0262820 CG43191 - http://flybase.org/reports/FBgn0262820 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43191, noncoding_6153" - CG43191 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016949 tilF touch insensitive larva F http://flybase.org/reports/FBgn0016949 - gene - - - "line 70, tilF" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" "embryonic/larval central nervous system,embryonic/larval peripheral nervous system" FBgn0010339 128up upstream of RpIII128 http://flybase.org/reports/FBgn0010339 "FBgn0010196, FBtr0087976, FBpp0087084" protein_coding_gene GTP binding ; GO:0005525 | inferred from direct assay - - "128up, X71866, CG8340, GTP-bp, Gtp-bp" "IPR004095:TGS, IPR005225:Small GTP-binding protein domain, IPR006073:GTP binding domain, IPR006074:GTP1/OBG, conserved site, IPR012676:TGS-like, IPR012675:Beta-grasp domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031167:OBG-type guanine nucleotide-binding (G) domain, IPR031662:GTP binding protein, second domain" CG8340 11-Aug-17 DroID_v2017_08 Drer\drg1 Scer\RBG1 Cele\T28D6.6 "Xtro\drg2, Xtro\drg1" "Mmus\Drg2, Mmus\Drg1" "Hsap\DRG2, Hsap\DRG1" " adult stage , embryonic stage " viable FBgn0038419 CG14879 - http://flybase.org/reports/FBgn0038419 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR001079 - - "BcDNA:RE20991, CG14879" "IPR001079:Galectin, carbohydrate recognition domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG14879 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0061193 Src64B::unc-5 Src64B::unc-5 http://flybase.org/reports/FBgn0061193 engineered_fusion_gene - - - Src64B::unc-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002887 mus201 mutagen-sensitive 201 http://flybase.org/reports/FBgn0002887 "FBgn0015712, FBgn0052956, FBtr0079668, FBpp0079283, FBtr0079669, FBpp0079284, FBtr0079670, FBpp0079285, FBtr0079671, FBpp0079286, FBtr0079672, FBpp0079287" protein_coding_gene endonuclease activity ; GO:0004519 | inferred from electronic annotation with InterPro:IPR001044 single-stranded DNA binding ; GO:0003697 | inferred from electronic annotation with InterPro:IPR001044 nucleotide-excision repair ; GO:0006289 | inferred from electronic annotation with InterPro:IPR001044 UV-damage excision repair ; GO:0070914 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001044 "DmXPG, xpg/mus201, XPG[Dm], XPG, mus-201, XPG[DM], ESTS:55A11T, 55A11T, rad202, mus(2)201, CG32956, CG10890, mus201" "IPR001044:XPG/Rad2 endonuclease, eukaryotes, IPR003903:Ubiquitin interacting motif, IPR006085:XPG N-terminal, IPR006086:XPG-I domain, IPR008918:Helix-hairpin-helix motif, class 2, IPR019974:XPG conserved site, IPR020045:5'-3' exonuclease, C-terminal domain, IPR006084:XPG/Rad2 endonuclease, IPR029060:PIN domain-like" CG10890 11-Aug-17 DroID_v2017_08 Drer\ercc5 "Scer\RAD2, Scer\YEN1" "Cele\gen-1, Cele\xpg-1" Xtro\ercc5 Mmus\Ercc5 "Hsap\ERCC5, Hsap\BIVM-ERCC5" "viable,chemical sensitive,recessive,DNA repair defective,fertile,lethal,partially,radiation sensitive,increased cell death,conditional,female fertile" "eye,conditional" FBgn0031885 Mnn1 Menin 1 http://flybase.org/reports/FBgn0031885 protein_coding_gene Y-form DNA binding ; GO:0000403 | inferred from biological aspect of ancestor with PANTHER:PTN000976222 histone-lysine N-methyltransferase activity ; GO:0018024 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000976222 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000976222 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN000976222 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000976222 "response to oxidative stress ; GO:0006979 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype proboscis development ; GO:0048728 | inferred from mutant phenotype mitotic G1 DNA damage checkpoint ; GO:0031571 | inferred from mutant phenotype nucleotide-excision repair ; GO:0006289 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred by curator from GO:0044665 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000976222 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype histone lysine methylation ; GO:0034968 | inferred from biological aspect of ancestor with PANTHER:PTN000976222 interstrand cross-link repair ; GO:0036297 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with Jra response to heat ; GO:0009408 | inferred from mutant phenotype response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype positive regulation of JNK cascade ; GO:0046330 | inferred from genetic interaction with kay response to salt stress ; GO:0009651 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from biological aspect of ancestor with PANTHER:PTN000976222" MLL1/2 complex ; GO:0044665 | inferred from direct assay chromatin ; GO:0000785 | inferred from biological aspect of ancestor with PANTHER:PTN000976222 nucleus ; GO:0005634 | inferred from direct assay "MEN1, menin, Menin1, CG33266, CG13778, Mnn1, mnn1, Menin, Mnn" "IPR007747:Menin, IPR011990:Tetratricopeptide-like helical domain" CG13778 11-Aug-17 DroID_v2017_08 Drer\men1 - - Xtro\men1 Mmus\Men1 Hsap\MEN1 "viable,fertile,stress response defective,chemical sensitive,lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage,lethal,conditional,radiation sensitive,DNA repair defective,wild-type,short lived,male,melanotic mass phenotype,lethal - all die before end of P-stage,some die during pharate adult stage" "distiproboscis,wing,adult thorax,chaeta" FBgn0000880 fs(1)M78 female sterile (1) M78 http://flybase.org/reports/FBgn0000880 - gene - - - fs(1)M78 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0263537 mir-4951 mir-4951 stem loop http://flybase.org/reports/FBgn0263537 miRNA_gene - - - "mir-4951, dme-mir-4951, CR43522" - CR43522 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031307 MFS3 Major Facilitator Superfamily Transporter 3 http://flybase.org/reports/FBgn0031307 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 cytosol ; GO:0005829 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "MFS3, CG4726" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG4726 11-Aug-17 DroID_v2017_08 "Drer\slc17a9a, Drer\slc17a6b, Drer\slc17a8, Drer\si:ch1073-513e17.1, Drer\slc17a5, Drer\slc17a6a, Drer\ppt1, Drer\slc17a7a" "Scer\DAL5, Scer\YIL166C, Scer\THI73, Scer\TNA1" "Cele\T01H3.3, Cele\M162.5, Cele\Y19D10A.8, Cele\Y19D10A.5, Cele\T19D12.9, Cele\Y4C6B.3, Cele\T28H11.8, Cele\slc-17.4, Cele\C01B4.8, Cele\Y15E3A.4, Cele\F41C3.2, Cele\vglu-2, Cele\C39E9.7, Cele\K11G9.5, Cele\C18H9.5, Cele\slc-17.5, Cele\T22F3.7, Cele\F10C2.7, Cele\T22F3.10, Cele\T22F3.8, Cele\vglu-3, Cele\F56A4.10, Cele\T02B11.6, Cele\eat-4, Cele\cima-1, Cele\C35A5.3, Cele\T19D12.10, Cele\Y4C6B.4, Cele\Y19D10A.4, Cele\W04C9.6, Cele\slc-17.1, Cele\M117.1, Cele\F11A5.9, Cele\Y19D10A.11, Cele\H11E01.2, Cele\T27D12.1, Cele\slc-17.8, Cele\T22F3.11, Cele\F59A1.13, Cele\slc-17.3, Cele\slc-17.9, Cele\K08C7.1, Cele\F56A4.12, Cele\R10D12.1, Cele\C01B4.7, Cele\C18D1.2, Cele\slc-17.2, Cele\Y51B9A.6, Cele\D1046.4, Cele\F44E7.7" Xtro\slc17a7 "Mmus\Slc17a3, Mmus\Slc17a7, Mmus\Slc17a2, Mmus\Slc17a5, Mmus\Slc17a4, Mmus\Slc17a6, Mmus\Slc17a1, Mmus\Slc17a8" "Hsap\SLC17A3, Hsap\SLC17A2, Hsap\SLC17A6, Hsap\SLC17A8, Hsap\SLC17A5, Hsap\SLC17A7, Hsap\SLC17A1, Hsap\SLC17A4" FBgn0050008 CG30008 - http://flybase.org/reports/FBgn0050008 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "CG12138, anon-WO0140519.246, CG30008" IPR002076:ELO family CG30008 11-Aug-17 DroID_v2017_08 "Drer\elovl7b, Drer\elovl1b, Drer\elovl8a, Drer\elovl4a, Drer\elovl7a, Drer\elovl5, Drer\elovl4b, Drer\elovl2, Drer\elovl8b, Drer\elovl1a" "Scer\ELO2, Scer\ELO1, Scer\ELO3" - "Xtro\elovl2, Xtro\elovl1, Xtro\elovl7, Xtro\elovl5" "Mmus\Elovl1, Mmus\Elovl5, Mmus\Elovl7, Mmus\Elovl2, Mmus\Elovl4" "Hsap\ELOVL7, Hsap\ELOVL4, Hsap\ELOVL2, Hsap\ELOVL5, Hsap\ELOVL1" viable FBgn0263525 mir-4911 mir-4911 stem loop http://flybase.org/reports/FBgn0263525 miRNA_gene - - - "mir-4911, dme-mir-4911, CR43510" - CR43510 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037231 Vps24 Vacuolar protein sorting 24 http://flybase.org/reports/FBgn0037231 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vacuolar transport ; GO:0007034 | inferred from electronic annotation with InterPro:IPR005024 phagocytosis ; GO:0006909 | inferred from mutant phenotype intralumenal vesicle formation ; GO:0070676 | inferred from sequence or structural similarity with SGD:S000001524 ESCRT III complex ; GO:0000815 | inferred from sequence or structural similarity with SGD:S000001524 "CG9779, Vps24, dvps24, DmVPS24, ESCRT, vps24" IPR005024:Snf7 family CG9779 11-Aug-17 DroID_v2017_08 Drer\chmp3 Scer\VPS24 Cele\vps-24 Xtro\chmp3 Mmus\Chmp3 "Hsap\CHMP3, Hsap\RNF103-CHMP3, Hsap\RNF103" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC12332 I -0.390687981 1.520651184 0.089116212 0.480321887 0.024683216 -0.458769256 FBgn0060774 l(3)S061301b lethal (3) S061301b http://flybase.org/reports/FBgn0060774 gene - - - "0613/01, l(3)S061301b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033145 CG12828 - http://flybase.org/reports/FBgn0033145 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12828 - CG12828 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065562 l(2)SH0987 lethal (2) SH0987 http://flybase.org/reports/FBgn0065562 gene - - - "l(2)SH0987, l(2)SH2 0987" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038914 fit female-specific independent of transformer http://flybase.org/reports/FBgn0038914 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Fit, CG17820, fit" - CG17820 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0041154 flk flanker http://flybase.org/reports/FBgn0041154 gene - - - flk - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004076 segB short egg B http://flybase.org/reports/FBgn0004076 - gene - - - segB - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060786 l(3)S059613 lethal (3) S059613 http://flybase.org/reports/FBgn0060786 gene - - - "0596/13, l(3)S059613" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016042 lup-4 loop unfolding protein 4 http://flybase.org/reports/FBgn0016042 - gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "ms(2)HA10, ms(2)HA30, lup-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,meiotic cell cycle defective,male" "Y chromosome loop,spermatocyte,spermatid,spermatozoon" FBgn0264988 CG44139 - http://flybase.org/reports/FBgn0264988 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44139 - CG44139 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022126 l(2)k06502 lethal (2) k06502 http://flybase.org/reports/FBgn0022126 FBgn0022292 gene - - - "l(2)02839, l(2)k06502" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044414 Scim13 Sensitized chromosome inheritance modifier 13 http://flybase.org/reports/FBgn0044414 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0032225 CG5022 - http://flybase.org/reports/FBgn0032225 protein_coding_gene cytoskeletal protein binding ; GO:0008092 | inferred from electronic annotation with InterPro:IPR000798 structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity actomyosin structure organization ; GO:0031032 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 extrinsic component of membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000798 cytoskeleton ; GO:0005856 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 CG5022 "IPR000299:FERM domain, IPR000798:Ezrin/radixin/moesin-like, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR014847:FERM adjacent (FA), IPR018980:FERM, C-terminal PH-like domain, IPR019748:FERM central domain, IPR018979:FERM, N-terminal, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain" CG5022 11-Aug-17 DroID_v2017_08 "Drer\epb41l4a, Drer\frmd6, Drer\LOC570903, Drer\epb41l4b, Drer\frmd5, Drer\frmd3" - Cele\frm-4 "Xtro\frmd5, Xtro\epb41l4a, Xtro\frmd3" "Mmus\Frmd6, Mmus\Frmd5, Mmus\Epb41l4a, Mmus\Frmd3" "Hsap\EPB41L4A, Hsap\FRMD6, Hsap\FRMD5, Hsap\FRMD3" viable FBgn0003656 sws swiss cheese http://flybase.org/reports/FBgn0003656 FBgn0004059 protein_coding_gene protein kinase A catalytic subunit binding ; GO:0034236 | inferred from physical interaction with Pka-C3 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P16912 lysophospholipase activity ; GO:0004622 | inferred from direct assay phospholipid metabolic process ; GO:0006644 | inferred from mutant phenotype glial cell apoptotic process ; GO:0034349 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype negative regulation of cAMP-dependent protein kinase activity ; GO:2000480 | inferred from mutant phenotype protein localization to membrane ; GO:0072657 | inferred from mutant phenotype neuron apoptotic process ; GO:0051402 | inferred from mutant phenotype phosphatidylcholine metabolic process ; GO:0046470 | inferred from direct assay ensheathment of neurons ; GO:0007272 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype membrane lipid metabolic process ; GO:0006643 | inferred from direct assay membrane organization ; GO:0061024 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "sws, olfE, CG2212, Sws, PNPLA6, SWS" "IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR001423:Lysophospholipase patatin, conserved site, IPR002641:Patatin-like phospholipase domain, IPR014710:RmlC-like jelly roll fold, IPR016035:Acyl transferase/acyl hydrolase/lysophospholipase" CG2212 11-Aug-17 DroID_v2017_08 "Drer\pnpla6, Drer\pnpla7b, Drer\pnpla7a" Scer\NTE1 "Cele\ZK370.4, Cele\M110.7" Xtro\pnpla6 "Mmus\Pnpla7, Mmus\Pnpla6" "Hsap\PNPLA6, Hsap\PNPLA7" " adult stage , embryonic stage -- adult stage " adult head

"viable,smell perception defective,recessive,neuroanatomy defective,short lived" "adult brain,cell body rind of lamina,neuropil,CNS glial cell,epithelial glial cell,eye photoreceptor cell" FBgn0022349 CG1910 - http://flybase.org/reports/FBgn0022349 "FBgn0061695, FBgn0062042" protein_coding_gene molecular_function ; GO:0003674 | no biological data available long-term memory ; GO:0007616 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "anon1A3, Anon1A3, 1A3, anon-WO0118547.745, anon-WO0118547.398, anon-EST:fe1A3, CG1910" IPR031945:Protein of unknown function DUF4775 CG1910 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "macrochaeta,trichogen cell" FBgn0061000 l(3)S026905 lethal (3) S026905 http://flybase.org/reports/FBgn0061000 gene - - - "0269/05, l(3)S026905" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0043995 Su(rst)D124 Su(rst)D124 http://flybase.org/reports/FBgn0043995 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D124, Su(rst)D124" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013446 fs(1)gammaa5 fs(1)gammaa5 http://flybase.org/reports/FBgn0013446 - gene - - - fs(1)gammaa5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015362 anon-k anon-k http://flybase.org/reports/FBgn0015362 - repeat_region - - - anon-k - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041732 mini-dumpy mini-dumpy http://flybase.org/reports/FBgn0041732 gene - - - mini-dumpy - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040235 c12.1 c12.1 http://flybase.org/reports/FBgn0040235 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:P78794 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with UniProtKB:P78794" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P78794 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG12135, c12.1, cwc15, C12.1" IPR006973:Pre-mRNA-splicing factor Cwf15/Cwc15 CG12135 11-Aug-17 DroID_v2017_08 Drer\cwc15 Scer\CWC15 "Cele\xtr-2, Cele\T10C6.5" Xtro\cwc15 Mmus\Cwc15 Hsap\CWC15 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0028512 BG:DS07721.1 BG:DS07721.1 http://flybase.org/reports/FBgn0028512 gene - - - "DS07721.1, BG:DS07721.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001338 l(1)1Bc lethal (1) 1Bc http://flybase.org/reports/FBgn0001338 - gene - - - "l(1)EC5, EC5, l(1)1Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005768 L12 L12 http://flybase.org/reports/FBgn0005768 - gene - - - L12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038956 CG5379 - http://flybase.org/reports/FBgn0038956 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from electronic annotation with InterPro:IPR018338 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR018338 - CG5379 "IPR001148:Alpha carbonic anhydrase, IPR018338:Carbonic anhydrase, alpha-class, conserved site, IPR023561:Carbonic anhydrase, alpha-class" CG5379 11-Aug-17 DroID_v2017_08 "Drer\ca14, Drer\ca15c, Drer\ca8, Drer\ca9, Drer\ca2, Drer\ca4b, Drer\ptprga, Drer\ca10b, Drer\zgc:153760, Drer\ca15b, Drer\ca4a, Drer\ca6, Drer\cahz, Drer\ca12, Drer\car15, Drer\ca10a, Drer\ca16b, Drer\ca5a, Drer\si:ch211-173d10.4, Drer\ca15a, Drer\ca7, Drer\ca4c" - "Cele\cah-6, Cele\cah-4, Cele\cah-3, Cele\cah-5" "Xtro\ca7, Xtro\ca10, Xtro\ca11, Xtro\ca4, Xtro\ca3, Xtro\ca5b, Xtro\ca14, Xtro\ca6, Xtro\ca2, Xtro\ca12, Xtro\LOC779564, Xtro\ca1, Xtro\ca8" "Mmus\Car12, Mmus\Ptprg, Mmus\Car6, Mmus\Car8, Mmus\Car13, Mmus\Car15, Mmus\Car5b, Mmus\Car9, Mmus\Car1, Mmus\Car11, Mmus\Car3, Mmus\Car5a, Mmus\Car2, Mmus\Car4, Mmus\Car7, Mmus\Car14, Mmus\Car10" "Hsap\CA5B, Hsap\CA14, Hsap\PTPRG, Hsap\CA9, Hsap\CA13, Hsap\CA2, Hsap\CA3, Hsap\CA10, Hsap\CA5A, Hsap\CA1, Hsap\CA8, Hsap\CA4, Hsap\CA12, Hsap\CA11, Hsap\CA7, Hsap\CA6" viable FBgn0016668 Hrp70 Hrp70 http://flybase.org/reports/FBgn0016668 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available nucleolus ; GO:0005730 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "hrp70, Hrp70" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019690 l(3)69Ai lethal (3) 69Ai http://flybase.org/reports/FBgn0019690 - gene - - - "l(3)69Ab, l(3)69Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265747 CR44554 - http://flybase.org/reports/FBgn0265747 non_protein_coding_gene - - - "CR44554, lincRNA.531" - CR44554 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022102 l(2)k07126 lethal (2) k07126 http://flybase.org/reports/FBgn0022102 - gene - - - l(2)k07126 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053401 5SrRNA:CR33401 5SrRNA:CR33401 http://flybase.org/reports/FBgn0053401 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33401, 5SrRNA:CR33401" - CR33401 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065760 l(2)SH0479 lethal (2) SH0479 http://flybase.org/reports/FBgn0065760 gene - - - "l(2)SH0479, l(2)SH2 0479" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036150 Ir68a Ionotropic receptor 68a http://flybase.org/reports/FBgn0036150 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir68a, CT19410, CG6185, DmelIR68a, IR68a" IPR001320:Ionotropic glutamate receptor CG6185 11-Aug-17 DroID_v2017_08 "Drer\grid2, Drer\grid1b, Drer\LOC100537813, Drer\grid1a" - - - "Mmus\Grik4, Mmus\Grid1" Hsap\GRID1 "viable,fertile" FBgn0260292 GSd436 - http://flybase.org/reports/FBgn0260292 gene - - - GSd436 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265206 T:Mito-CG9393 Mitochondrial outer membrane targeting sequence of CG9393 http://flybase.org/reports/FBgn0265206 engineered_tag - - - T:Mito-CG9393 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032870 CG2608 - http://flybase.org/reports/FBgn0032870 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001374 - - "38D.26, CG2608" "IPR001374:R3H domain, IPR017330:Sperm-associated antigen 7, IPR034068:Sperm-associated antigen 7, R3H domain" CG2608 11-Aug-17 DroID_v2017_08 Drer\spag7 - - - Mmus\Spag7 Hsap\SPAG7 "viable,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0260501 Pkn::Mmus\Rtkn - http://flybase.org/reports/FBgn0260501 engineered_fusion_gene - - - "Pkn::Mmus\Rtkn, Rhot-Pkn" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002354 l(3)87Df lethal (3) 87Df http://flybase.org/reports/FBgn0002354 "FBgn0038112, FBgn0062841" protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from biological aspect of ancestor with PANTHER:PTN001269069 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN001269069 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001269069 "l(3)S12, l(3)s12, S12, CG7620, BcDNA:SD27354, l(3)87Df" "IPR022533:Cox20/FAM36A, IPR023242:FAM36A" CG7620 11-Aug-17 DroID_v2017_08 Drer\cox20 Scer\COX20 - Xtro\cox20 Mmus\Cox20 Hsap\COX20 "viable,fertile,wild-type,lethal,recessive,cold sensitive,female sterile,partially,heat sensitive" macrochaeta FBgn0038438 Der-2 Derlin-2 http://flybase.org/reports/FBgn0038438 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR022764 molecular_function ; GO:0003674 | no biological data available endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from sequence or structural similarity with HGNC:17943 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from sequence or structural similarity with HGNC:17943 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from sequence or structural similarity with HGNC:17943 "DER1, Der-2, CG14899, Cg14899" "IPR007599:Derlin, IPR022764:Peptidase S54, rhomboid domain" CG14899 11-Aug-17 DroID_v2017_08 "Drer\derl2, Drer\derl3, Drer\derl1" "Scer\DER1, Scer\DFM1" "Cele\cup-2, Cele\R151.6" "Xtro\derl2, Xtro\derl1" "Mmus\Derl1, Mmus\Derl3, Mmus\Derl2" "Hsap\DERL3, Hsap\DERL2, Hsap\DERL1" FBgn0069231 gl(2L)260-24 gl(2L)260-24 http://flybase.org/reports/FBgn0069231 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)260-24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0003362 sesE stress-sensitive E http://flybase.org/reports/FBgn0003362 - gene - - - sesE - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,paralytic,somatic clone,behavior defective" "leg,somatic clone" FBgn0003486 spo spook http://flybase.org/reports/FBgn0003486 FBgn0035618 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from sequence model oxidoreductase activity ; GO:0016491 | inferred from sequence model" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 midgut development ; GO:0007494 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype embryonic digestive tract development ; GO:0048566 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay "Cyp307a1, CYP307A1-Dm, 307a1, Spo, CG10594, spo, Dmspo, spook, CYP307A1" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG10594 11-Aug-17 DroID_v2017_08 "Drer\cyp1d1, Drer\cyp2x6, Drer\cyp2x7, Drer\cyp2aa12, Drer\cyp21a2, Drer\cyp2p8, Drer\cyp2k16, Drer\cyp2p6, Drer\cyp2x8, Drer\cyp2k21, Drer\cyp2u1, Drer\cyp2k31, Drer\cyp1b1, Drer\si:zfos-411a11.2, Drer\cyp2aa2, Drer\cyp2p7, Drer\cyp2aa6, Drer\cyp2j20, Drer\cyp2n13, Drer\cyp17a1, Drer\cyp2k18, Drer\cyp2k20, Drer\cyp2x10.2, Drer\cyp2aa1, Drer\cyp2x9, Drer\cyp2x12, Drer\cyp1a, Drer\cyp2k19, Drer\cyp2aa11, Drer\cyp2ad6, Drer\cyp2r1, Drer\cyp17a2, Drer\cyp2aa8, Drer\cyp2k22, Drer\cyp2y3, Drer\cyp2aa4, Drer\cyp2k17, Drer\cyp2k8, Drer\cyp2aa3, Drer\cyp2aa9, Drer\cyp2ad2, Drer\cyp2ae1, Drer\si:dkey-286h2.7, Drer\LOC100148115" - Cele\cyp-14A4 "Xtro\cyp2b6, Xtro\cyp21a2.1, Xtro\LOC100486127, Xtro\cyp2c8.1, Xtro\cyp2d6, Xtro\cyp2g1p, Xtro\LOC100493194, Xtro\cyp1a1, Xtro\cyp2c8.2, Xtro\LOC100036663, Xtro\cyp2u1, Xtro\MGC107969, Xtro\LOC100145323, Xtro\cyp2j2, Xtro\LOC100145541, Xtro\LOC548374, Xtro\cyp2e1, Xtro\cyp2f2, Xtro\cyp2a13, Xtro\LOC100497460, Xtro\LOC100497184, Xtro\LOC100145084, Xtro\cyp2a6, Xtro\LOC100145695, Xtro\cyp1b1, Xtro\cyp1d1, Xtro\cyp2r1, Xtro\MGC69353, Xtro\cyp2w1, Xtro\LOC619584, Xtro\MGC69416, Xtro\cyp17a1" "Mmus\Cyp2b10, Mmus\Cyp2d22, Mmus\Cyp2e1, Mmus\Cyp2d40, Mmus\Cyp2d10, Mmus\Cyp2j11, Mmus\Cyp2c39, Mmus\Cyp2b23, Mmus\Cyp2c66, Mmus\Cyp2b9, Mmus\Cyp2j8, Mmus\Cyp2c50, Mmus\Cyp2j12, Mmus\Cyp2j5, Mmus\Cyp2c55, Mmus\Cyp2b13, Mmus\Cyp2c68, Mmus\Cyp2d34, Mmus\Cyp17a1, Mmus\Cyp1a2, Mmus\Cyp2c54, Mmus\Cyp1a1, Mmus\Cyp21a1, Mmus\Cyp2j13, Mmus\Cyp2u1, Mmus\Cyp2a22, Mmus\Cyp2c67, Mmus\Cyp2a12, Mmus\Cyp2c44, Mmus\Cyp2c37, Mmus\Cyp2c65, Mmus\Cyp2d26, Mmus\Cyp2c70, Mmus\Cyp2r1, Mmus\Cyp2s1, Mmus\Cyp2d11, Mmus\Cyp2d9, Mmus\Cyp2j6, Mmus\Cyp2c40, Mmus\Cyp1b1, Mmus\Cyp2b19, Mmus\Cyp2a5, Mmus\Cyp2j9, Mmus\Cyp2ab1, Mmus\Cyp2c29, Mmus\Cyp2g1, Mmus\Cyp2w1, Mmus\Cyp2a4, Mmus\Cyp2c38, Mmus\Cyp2d12, Mmus\Cyp2f2, Mmus\Cyp2c69, Mmus\Cyp2t4" "Hsap\CYP2F1, Hsap\CYP1A2, Hsap\CYP2C9, Hsap\CYP2A7, Hsap\CYP2W1, Hsap\CYP21A2, Hsap\CYP2U1, Hsap\CYP2C19, Hsap\CYP17A1, Hsap\CYP2R1, Hsap\CYP2E1, Hsap\CYP2A6, Hsap\CYP3A43, Hsap\CYP2S1, Hsap\CYP2C8, Hsap\CYP2A13, Hsap\CYP1B1, Hsap\CYP2C18, Hsap\CYP1A1, Hsap\CYP2D6, Hsap\CYP2B6, Hsap\CYP2J2" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,fertile,lethal" "embryonic/larval midgut,presumptive embryonic/larval central nervous system,commissure,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,cephalopharyngeal skeleton,embryonic/first instar larval cuticle,dorsal closure embryo,embryonic ventral epidermis,ventral nerve cord,embryonic/larval foregut,embryonic/larval hindgut,longitudinal connective,glial cell,midline glial cell,ectopic,midgut primordium,denticle belt,embryonic hindgut" FBgn0263250 CG43393 - http://flybase.org/reports/FBgn0263250 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43393 - CG43393 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038862 Usp8 Ubiquitin specific protease 8 http://flybase.org/reports/FBgn0038862 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from genetic interaction with smo protein deubiquitination ; GO:0016579 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CT18196, USP8, CG5798, dUBPY, usp8, UBPY, UBPY/USP8, UbpY, Usp8, Ubpy, Q9VDD8, ubpy" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR001763:Rhodanese-like domain, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain, IPR015063:USP8 dimerisation domain" CG5798 11-Aug-17 DroID_v2017_08 "Drer\usp2a, Drer\usp32, Drer\usp2b, Drer\usp8, Drer\usp11, Drer\usp4, Drer\usp1, Drer\usp21, Drer\usp43b" "Scer\DOA4, Scer\UBP8, Scer\UBP7, Scer\UBP11, Scer\UBP5, Scer\UBP12" "Cele\usp-3, Cele\cyk-3, Cele\F07A11.4, Cele\H34C03.2, Cele\usp-50, Cele\usp-33" "Xtro\usp21, Xtro\usp8, Xtro\usp2, Xtro\usp15, Xtro\usp37" "Mmus\Usp8, Mmus\Usp22, Mmus\Usp15, Mmus\Usp1, Mmus\Usp32, Mmus\Usp27x, Mmus\Usp26, Mmus\Usp3, Mmus\Usp21, Mmus\Usp29, Mmus\Usp37, Mmus\Usp4, Mmus\Usp43, Mmus\Usp2, Mmus\Usp50, Mmus\Usp11" "Hsap\USP11, Hsap\USP26, Hsap\USP21, Hsap\USP3, Hsap\USP29, Hsap\USP43, Hsap\USP4, Hsap\USP37, Hsap\USP50, Hsap\USP22, Hsap\USP8, Hsap\USP27X, Hsap\USP1, Hsap\USP2, Hsap\USP32" "visible,locomotor rhythm defective,lethal,lethal - all die before end of pupal stage,somatic clone,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" "wing,wing vein L3,wing margin bristle" FBgn0262077 JC09 - http://flybase.org/reports/FBgn0262077 gene - response to anesthetic ; GO:0072347 | inferred from mutant phenotype - JC09 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0000724 fr fringed http://flybase.org/reports/FBgn0000724 - gene - - - fr - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive,viable,reduced,female semi-sterile,female sterile,poor,male sterile" "wing,dorsal row,ventral row,adult abdomen,eye,macrochaeta" FBgn0028249 l(3)93Bj lethal (3) 93Bj http://flybase.org/reports/FBgn0028249 gene - - - l(3)93Bj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039420 CG6154 - http://flybase.org/reports/FBgn0039420 protein_coding_gene dipeptidase activity ; GO:0016805 | inferred from biological aspect of ancestor with PANTHER:PTN000047764 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008257 - CG6154 "IPR008257:Renal dipeptidase family, IPR032466:Metal-dependent hydrolase" CG6154 11-Aug-17 DroID_v2017_08 "Drer\dpep1, Drer\dpep2" - Cele\math-31 "Xtro\dpep1, Xtro\dpep2" "Mmus\Dpep3, Mmus\Dpep2, Mmus\Dpep1" "Hsap\DPEP1, Hsap\DPEP3, Hsap\DPEP2" viable FBgn0085552 CG41010 - http://flybase.org/reports/FBgn0085552 protein_coding_gene - - - CG41010 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263747 CG43672 - http://flybase.org/reports/FBgn0263747 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 "CG43672, CG8473, CG33173" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR026082:ABC transporter A, ABCA" CG43672 11-Aug-17 DroID_v2017_08 "Drer\abca3b, Drer\abca12, Drer\abca1b, Drer\abca5, Drer\abch1, Drer\abca1a, Drer\abca2" - "Cele\abt-2, Cele\abt-1" "Xtro\abca9, Xtro\abca8, Xtro\abca1, Xtro\abca10, Xtro\abca4, Xtro\abca2, Xtro\abca3" "Mmus\Abca13, Mmus\Abca5, Mmus\Abca9, Mmus\Abca8b, Mmus\Abca8a, Mmus\Abca16, Mmus\Abca1, Mmus\Abca2, Mmus\Abca12, Mmus\Abca3, Mmus\Abca17, Mmus\Abca4, Mmus\Abca7, Mmus\Abca14, Mmus\Abca15, Mmus\Abca6" "Hsap\ABCA9, Hsap\ABCA4, Hsap\ABCA1, Hsap\ABCA13, Hsap\ABCA10, Hsap\ABCA8, Hsap\ABCA2, Hsap\ABCA6, Hsap\ABCA3, Hsap\ABCA5, Hsap\ABCA7, Hsap\ABCA12" "partially lethal - majority die,some die during pupal stage,viable,visible" "chaeta,supernumerary" FBgn0032748 CG10492 - http://flybase.org/reports/FBgn0032748 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - "TuB1, TU37B1, B1, anon-37B-1, CG10492" "IPR001878:Zinc finger, CCHC-type" CG10492 11-Aug-17 DroID_v2017_08 "Drer\zcchc14, Drer\zcchc2" - Cele\gls-1 Xtro\zcchc2 "Mmus\Zcchc2, Mmus\Zcchc14" "Hsap\ZCCHC14, Hsap\ZCCHC2" "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0038575 CG7208 - http://flybase.org/reports/FBgn0038575 protein_coding_gene - - - "CG7208, CG 7208" IPR031961:Domain of unknown function DUF4780 CG7208 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028916 CG33090 - http://flybase.org/reports/FBgn0028916 protein_coding_gene beta-glucosidase activity ; GO:0008422 | inferred from sequence or structural similarity with UniProtKB:Q9HCG7 glycoside catabolic process ; GO:0016139 | inferred from sequence or structural similarity with UniProtKB:Q9HCG7 bile acid metabolic process ; GO:0008206 | inferred from sequence or structural similarity with UniProtKB:Q9HCG7 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9HCG7 "BG:DS01068.2, CG7469, CG31837, CG15287, CG33090" "IPR008928:Six-hairpin glycosidase-like, IPR024462:Glycosyl-hydrolase family 116, N-terminal, IPR006775:Glycosyl-hydrolase family 116, catalytic region" CG33090 11-Aug-17 DroID_v2017_08 Drer\gba2 - "Cele\hpo-13, Cele\R08F11.1" Xtro\gba2 Mmus\Gba2 Hsap\GBA2 "viable,fertile,male" FBgn0041736 l(3)63Eg lethal (3) 63Eg http://flybase.org/reports/FBgn0041736 gene - - - "group III, l(3)63Eg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037703 JHDM2 JmjC domain-containing histone demethylase 2 http://flybase.org/reports/FBgn0037703 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from biological aspect of ancestor with PANTHER:PTN000284569 histone demethylase activity (H3-K9 specific) ; GO:0032454 | inferred from mutant phenotype transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from biological aspect of ancestor with PANTHER:PTN000284569 histone demethylase activity ; GO:0032452 | inferred from sequence model histone demethylation ; GO:0016577 | inferred from sequence model histone H3-K9 demethylation ; GO:0033169 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok nucleus ; GO:0005634 | inferred from sequence model nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000284569 chromatin ; GO:0000785 | inferred from direct assay "CG31123, CG8165, JHDM2" IPR003347:JmjC domain CG8165 11-Aug-17 DroID_v2017_08 "Drer\kdm3b, Drer\jmjd1cb, Drer\jmjd1ca" - "Cele\R10E8.3, Cele\C05C12.5, Cele\C01B9.1, Cele\fbxa-134, Cele\F57G4.1, Cele\R10E8.2" "Xtro\jmjd1c, Xtro\kdm3b, Xtro\kdm3a" "Mmus\Kdm3a, Mmus\Kdm3b, Mmus\Jmjd1c, Mmus\Hr" "Hsap\KDM3A, Hsap\KDM3B, Hsap\JMJD1C, Hsap\HR" "viable,fertile" FBgn0038279 Sdr Secreted decoy of InR http://flybase.org/reports/FBgn0038279 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006211 transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from electronic annotation with InterPro:IPR006211 insulin-like growth factor binding ; GO:0005520 | inferred from physical interaction with Ilp3 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from electronic annotation with InterPro:IPR006211 protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR006211 negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006211 extracellular space ; GO:0005615 | inferred from direct assay "Sdr, CG3837" "IPR000494:Receptor L-domain, IPR006211:Furin-like cysteine-rich domain, IPR003961:Fibronectin type III, IPR032675:Leucine-rich repeat domain, L domain-like, IPR013783:Immunoglobulin-like fold" CG3837 11-Aug-17 DroID_v2017_08 "Drer\LOC100329589, Drer\ephb6, Drer\epha7, Drer\epha2b, Drer\epha6, Drer\epha5, Drer\ephb3, Drer\igf1rb, Drer\epha4l, Drer\epha8, Drer\epha2a, Drer\ek1, Drer\ephb4b, Drer\ephb2b, Drer\ephb4a, Drer\ephb2a, Drer\insra, Drer\epha4b, Drer\igf1ra, Drer\insrb, Drer\ephb3a, Drer\epha4a" - "Cele\vab-1, Cele\daf-2, Cele\ddr-2, Cele\rol-3, Cele\F09A5.2" "Xtro\igf1r, Xtro\insrr, Xtro\insr" "Mmus\Epha8, Mmus\Epha6, Mmus\Epha3, Mmus\Ephb1, Mmus\Epha7, Mmus\Igf1r, Mmus\Insr, Mmus\Epha10, Mmus\Epha1, Mmus\Epha5, Mmus\Ephb3, Mmus\Ros1, Mmus\Ephb2, Mmus\Ephb4, Mmus\Insrr, Mmus\Epha4, Mmus\Epha2" "Hsap\EPHB4, Hsap\EPHA4, Hsap\INSR, Hsap\INSRR, Hsap\EPHA10, Hsap\EPHA3, Hsap\EPHA5, Hsap\EPHB3, Hsap\EPHB2, Hsap\EPHA6, Hsap\EPHA7, Hsap\EPHA1, Hsap\IGF1R, Hsap\ROS1, Hsap\EPHA2, Hsap\EPHB1, Hsap\EPHA8" "large body,size defective,decreased cell size,viable,increased cell size,increased cell number,visible" "trichogen cell,mesothoracic tergum" FBgn0050267 CR30267 - http://flybase.org/reports/FBgn0050267 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT28638, CG30267, CR30267" - CR30267 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033867 Cpr50Ca Cuticular protein 50Ca http://flybase.org/reports/FBgn0033867 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr50Ca, CG13338" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG13338 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263562 mir-4948 mir-4948 stem loop http://flybase.org/reports/FBgn0263562 miRNA_gene - - - "mir-4948, dme-mir-4948, CR43547" - CR43547 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011099 l(1)Q59 lethal (1) Q59 http://flybase.org/reports/FBgn0011099 FBgn0010210 gene - - - l(1)Q59 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003305 raised-wing raised wing http://flybase.org/reports/FBgn0003305 - gene - - - "rw, raised-wing" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced" wing FBgn0022321 l(1)B6.1 lethal (1) B6.1 http://flybase.org/reports/FBgn0022321 - gene - - - "B6.1, l(1)B6.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032793 CG10189 - http://flybase.org/reports/FBgn0032793 protein_coding_gene tRNA binding ; GO:0000049 | inferred from electronic annotation with InterPro:IPR019407 sulfurtransferase activity ; GO:0016783 | inferred from biological aspect of ancestor with PANTHER:PTN000466898 tRNA thio-modification ; GO:0034227 | inferred from sequence or structural similarity with UniProtKB:P53923 tRNA wobble uridine modification ; GO:0002098 | inferred from sequence or structural similarity with UniProtKB:P53923 tRNA wobble position uridine thiolation ; GO:0002143 | inferred from biological aspect of ancestor with PANTHER:PTN000466898 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000466898 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P53923 "i180, i199, CG10189" "IPR019407:Cytoplasmic tRNA 2-thiolation protein 2, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG10189 11-Aug-17 DroID_v2017_08 Drer\ctu2 "Scer\NCS6, Scer\NCS2" Cele\tut-2 Xtro\ctu2 "Mmus\Ctu2, Mmus\Ctu1" "Hsap\CTU1, Hsap\CTU2" "viable,fertile" FBgn0000001 4.5SRNA 4.5SRNA http://flybase.org/reports/FBgn0000001 - non_protein_coding_gene - - - 4.5SRNA - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025683 CG3164 - http://flybase.org/reports/FBgn0025683 FBgn0031221 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CK02656, BEST:CK02656, CG3164" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG3164 11-Aug-17 DroID_v2017_08 "Drer\abcg8, Drer\abcg4b, Drer\abcg4a, Drer\abcg2c, Drer\abcg5, Drer\abcg1, Drer\abcg2b, Drer\abcg2a" "Scer\YOL075C, Scer\SNQ2, Scer\PDR10, Scer\PDR15, Scer\ADP1, Scer\PDR18" "Cele\wht-3, Cele\wht-7, Cele\wht-8, Cele\wht-4, Cele\wht-6, Cele\wht-1, Cele\abch-1" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg3, Mmus\Abcg1, Mmus\Abcg2, Mmus\Abcg5, Mmus\Abcg8, Mmus\Abcg4" "Hsap\ABCG4, Hsap\ABCG5, Hsap\ABCG8, Hsap\ABCG2, Hsap\ABCG1" "viable,partially lethal - majority die" FBgn0039199 CG13615 - http://flybase.org/reports/FBgn0039199 protein_coding_gene - - - CG13615 IPR006631:Protein of unknown function DM4/12 CG13615 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC24018 K -0.438474938 -0.297190115 -0.408138967 -0.275194658 2.451486296 -0.102750772 FBgn0027622 297\pol 297 element pol http://flybase.org/reports/FBgn0027622 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001969 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001969 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "297\pol, pol" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR001969:Aspartic peptidase, active site, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035213 CG2199 - http://flybase.org/reports/FBgn0035213 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG2199, FBpp0072605" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG2199 11-Aug-17 DroID_v2017_08 "Drer\im:7147486, Drer\znf142" Scer\RME1 - - "Mmus\Zfp142, Mmus\Zfp574" "Hsap\ZNF574, Hsap\ZNF142, Hsap\TP63" "viable,visible" trichogen cell FBgn0013526 l(2)23AB4 lethal (2) 23AB4 http://flybase.org/reports/FBgn0013526 - gene - - - "l(2)23Af, l(2)23AB4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259463 C442 - http://flybase.org/reports/FBgn0259463 gene - - - C442 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0050049 CG30049 - http://flybase.org/reports/FBgn0050049 protein_coding_gene - - cellular_component ; GO:0005575 | no biological data available "CG30049, CG30049-PA" IPR007484:Peptidase M28 CG30049 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\YDR415C, Scer\VPS70, Scer\APE3, Scer\PFF1" "Cele\B0495.7, Cele\C44B7.11" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable DRSC21345 I 0.419832993 -1.923645196 0.164386021 1.429592861 0.038733218 -0.622010035 FBgn0046630 anon-38E.6 anon-38E.6 http://flybase.org/reports/FBgn0046630 gene - - - "38E.6, anon-38E.6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066341 mirta mirta http://flybase.org/reports/FBgn0066341 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mirta - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0002648 mar metaphase arrest http://flybase.org/reports/FBgn0002648 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mar - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0028569 robl37BC robl37BC http://flybase.org/reports/FBgn0028569 protein_coding_gene "dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity dynein intermediate chain binding ; GO:0045505 | inferred from sequence or structural similarity with robl" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with robl microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from sequence or structural similarity with robl dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG15171, robl37BC, Robl37BC" IPR004942:Roadblock/LAMTOR2 domain CG15171 11-Aug-17 DroID_v2017_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb1, Xtro\dynlrb2" "Mmus\Dynlrb1, Mmus\Dynlrb2" "Hsap\DYNLRB1, Hsap\DYNLRB2" viable FBgn0015350 CG10349 - http://flybase.org/reports/FBgn0015350 - protein_coding_gene - - - "CG-CG10349, CT29078, II, anon-89Ea, CG10349" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0065594 l(2)SH0895 lethal (2) SH0895 http://flybase.org/reports/FBgn0065594 gene - - - "l(2)SH0895, l(2)SH2 0895" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060854 l(3)S048319 lethal (3) S048319 http://flybase.org/reports/FBgn0060854 gene - - - "0483/19, l(3)S048319" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0025147 ms(2)A9 ms(2)A9 http://flybase.org/reports/FBgn0025147 - gene - - - ms(2)A9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0016698 Ptpa Phosphotyrosyl phosphatase activator http://flybase.org/reports/FBgn0016698 - protein_coding_gene protein tyrosine phosphatase activator activity ; GO:0008160 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 regulation of asymmetric protein localization involved in cell fate determination ; GO:1904785 | inferred from mutant phenotype basal protein localization ; GO:0045175 | inferred from mutant phenotype mitotic spindle organization in nucleus ; GO:0030472 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 protein phosphatase type 2A complex ; GO:0000159 | inferred from sequence or structural similarity with UniProtKB:Q15257 protein phosphatase type 2A complex ; GO:0000159 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 "PTPA, DPTPA, CG3289, Ptpa" "IPR004327:Phosphotyrosyl phosphatase activator, PTPA" CG3289 11-Aug-17 DroID_v2017_08 Drer\ppp2r4 "Scer\RRD2, Scer\RRD1" Cele\Y71H2AM.20 Xtro\ppp2r4 Mmus\Ptpa Hsap\PTPA "viable,planar polarity defective" FBgn0035638 Tektin-C Tektin C http://flybase.org/reports/FBgn0035638 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity cilium movement involved in cell motility ; GO:0060294 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 flagellated sperm motility ; GO:0030317 | inferred from biological aspect of ancestor with PANTHER:PTN000462268 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity sperm flagellum ; GO:0036126 | inferred from biological aspect of ancestor with PANTHER:PTN000462268 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 "CG10541, Tektin-C" IPR000435:Tektin CG10541 11-Aug-17 DroID_v2017_08 "Drer\tekt3, Drer\tekt2, Drer\tekt4, Drer\tekt1" Scer\SPC110 Cele\R02E12.4 "Xtro\tekt1, Xtro\tekt4, Xtro\tekt2, Xtro\tekt3" "Mmus\Tekt2, Mmus\Tekt1, Mmus\Tekt3, Mmus\Tekt5, Mmus\Tekt4" "Hsap\TEKT4, Hsap\TEKT5, Hsap\TEKT1, Hsap\TEKT2, Hsap\TEKT3" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC09741 EK -0.80103823 -0.161306532 1.067311886 -3.731354252 1.74754327 0.915708564 FBgn0262524 ver verrocchio http://flybase.org/reports/FBgn0262524 protein_coding_gene single-stranded telomeric DNA binding ; GO:0043047 | contributes_to inferred from direct assay "telomere capping ; GO:0016233 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred by curator from GO:0000782,GO:0043047" "telomere cap complex ; GO:0000782 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay" "ver, CG14121, 1479/10, anon-WO0172774.89, anon-WO0172774.87, anon-WO0172774.86, l(3)S147910, Ver" - CG14121 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086324 JR8 - http://flybase.org/reports/FBgn0086324 gene - - - JR8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0003983 Vm34Ca Vitelline membrane 34Ca http://flybase.org/reports/FBgn0003983 - protein_coding_gene - - - "Vm34Ca, VM34C, VM26A.1, VM34C.1, Vm34C, CG9271, Vm34Cc" IPR013135:Vitelline membrane cysteine-rich domain CG9271 11-Aug-17 DroID_v2017_08 - - - - - - oogenesis stage | stage S8-10 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0082675 E(fu) Enhancer of fused http://flybase.org/reports/FBgn0082675 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available E(fu) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039622 eIF4E6 eukaryotic translation initiation factor 4E6 http://flybase.org/reports/FBgn0039622 protein_coding_gene "translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR001040, InterPro:IPR019770 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation repressor activity ; GO:0030371 | traceable author statement RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay eukaryotic initiation factor 4G binding ; GO:0031370 | NOT inferred from direct assay RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity" "translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR001040, InterPro:IPR019770 negative regulation of translation ; GO:0017148 | traceable author statement" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001040, InterPro:IPR019770 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity" "CG1442, eIF4E, BcDNA:RH55324, eIF4E6, eIF4E-6" "IPR001040:Translation Initiation factor eIF- 4e, IPR023398:Translation Initiation factor eIF- 4e-like, IPR019770:Eukaryotic translation initiation factor 4E (eIF-4E), conserved site" CG1442 11-Aug-17 DroID_v2017_08 "Drer\eif4ea, Drer\sesn1, Drer\sesn2, Drer\eif4e1c, Drer\eif4e1b, Drer\eif4e3, Drer\eif4eb, Drer\si:zfos-80g12.1" Scer\CDC33 "Cele\ife-1, Cele\ife-5, Cele\ife-3, Cele\ife-2" "Xtro\sesn3, Xtro\sesn1, Xtro\eif4e, Xtro\eif4e1b" "Mmus\Eif4e1b, Mmus\Eif4e, Mmus\Sesn3, Mmus\Eif4e3, Mmus\Sesn2, Mmus\Sesn1" "Hsap\SESN3, Hsap\SESN1, Hsap\EIF4E3, Hsap\EIF4E, Hsap\EIF4E1B, Hsap\SESN2" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0051139 CG31139 - http://flybase.org/reports/FBgn0051139 protein_coding_gene UDP-xylosyltransferase activity ; GO:0035252 | inferred from biological aspect of ancestor with PANTHER:PTN000954275 UDP-glucosyltransferase activity ; GO:0035251 | inferred from sequence or structural similarity with HGNC:22954 UDP-glucosyltransferase activity ; GO:0035251 | inferred from biological aspect of ancestor with PANTHER:PTN000954275 protein O-linked glycosylation ; GO:0006493 | inferred from sequence or structural similarity with HGNC:22954 glycolipid metabolic process ; GO:0006664 | inferred from biological aspect of ancestor with PANTHER:PTN000258330 protein O-linked glycosylation ; GO:0006493 | inferred from biological aspect of ancestor with PANTHER:PTN000258397 positive regulation of Notch signaling pathway ; GO:0045747 | inferred from biological aspect of ancestor with PANTHER:PTN000258397 endoplasmic reticulum lumen ; GO:0005788 | inferred from sequence or structural similarity with HGNC:22954 endoplasmic reticulum lumen ; GO:0005788 | inferred from biological aspect of ancestor with PANTHER:PTN000258341 "CG17138, BcDNA:AT07872, CG31139" IPR006598:Lipopolysaccharide-modifying protein CG31139 11-Aug-17 DroID_v2017_08 "Drer\poglut1, Drer\kdelc1, Drer\kdelc2" - - "Xtro\kdelc2, Xtro\kdelc1" "Mmus\Kdelc1, Mmus\Poglut1, Mmus\Kdelc2" "Hsap\KDELC2, Hsap\POGLUT1, Hsap\KDELC1" FBgn0261461 RhoGAP18B Rho GTPase activating protein at 18B http://flybase.org/reports/FBgn0261461 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from direct assay Rho GTPase binding ; GO:0017048 | inferred from physical interaction with Rac1 inferred from physical interaction with Cdc42 inferred from physical interaction with Rho1 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000571279 "RhoGAP18B, CG7481, whir, 5-131, CG42274, CG7531, CG17015, CG7502" "IPR000198:Rho GTPase-activating protein domain, IPR008936:Rho GTPase activation protein" CG42274 11-Aug-17 DroID_v2017_08 "Drer\gmip, Drer\racgap1, Drer\arhgap15, Drer\arhgap12a, Drer\hmha1b, Drer\arhgap29a, Drer\arhgap29b, Drer\hmha1a, Drer\arhgap27l, Drer\syde1, Drer\arhgap12b, Drer\arhgap9, Drer\syde2, Drer\si:ch1073-416j23.1" "Scer\RGD1, Scer\BEM3, Scer\RGA2, Scer\RGA1, Scer\ECM25" "Cele\srgp-1, Cele\spv-1" "Xtro\hmha1, Xtro\arhgap29, Xtro\arhgap12, Xtro\gmip, Xtro\racgap1, Xtro\arhgap27" "Mmus\Arhgap29, Mmus\Syde2, Mmus\Racgap1, Mmus\Gmip, Mmus\Hmha1, Mmus\Arhgap27, Mmus\Arhgap15, Mmus\Arhgap9, Mmus\Arhgap12, Mmus\Syde1" "Hsap\ARHGAP29, Hsap\SYDE1, Hsap\RACGAP1, Hsap\ARHGAP9, Hsap\GMIP, Hsap\ARHGAP15, Hsap\SYDE2, Hsap\ARHGAP12, Hsap\ARHGAP27, Hsap\ARHGAP45" FBgn0036052 CG10809 - http://flybase.org/reports/FBgn0036052 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10809 "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG10809 11-Aug-17 DroID_v2017_08 "Drer\ankrd46b, Drer\ankrd54" "Scer\NAS6, Scer\SPT23" - - "Mmus\Ankrd61, Mmus\Ankrd54, Mmus\Ankrd46" "Hsap\ANKRD46, Hsap\ANKRD61, Hsap\ANKRD54" "viable,fertile" FBgn0017433 anon-4Ba anon-4Ba http://flybase.org/reports/FBgn0017433 - gene - - - anon-4Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069424 JJF025 JJF025 http://flybase.org/reports/FBgn0069424 gene - - - JJF025 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0263708 CR43660 - http://flybase.org/reports/FBgn0263708 non_protein_coding_gene - - - "CR43660, lincRNA.336" - CR43660 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029819 Usp30 Ubiquitin specific protease 30 http://flybase.org/reports/FBgn0029819 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with MGI:MGI:2144157 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein K11-linked deubiquitination ; GO:0035871 | inferred from sequence or structural similarity with UniProtKB:Q70CQ3 protein K6-linked deubiquitination ; GO:0044313 | inferred from sequence or structural similarity with UniProtKB:Q70CQ3 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with MGI:MGI:2144157 response to paraquat ; GO:1901562 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG3016, dUSP30, Usp30, USP30, Q9W462" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG3016 11-Aug-17 DroID_v2017_08 "Drer\usp3, Drer\usp49, Drer\usp44, Drer\usp30, Drer\LOC100537262" "Scer\UBP16, Scer\UBP1, Scer\UBP8" Cele\Y67D2.2 "Xtro\usp30, Xtro\usp22, Xtro\usp3, Xtro\usp44, Xtro\usp49" "Mmus\Usp30, Mmus\Usp3, Mmus\Usp44, Mmus\Usp22, Mmus\Usp49, Mmus\Usp27x, Mmus\Usp51" "Hsap\USP30, Hsap\USP22, Hsap\USP51, Hsap\USP49, Hsap\USP44, Hsap\USP3" "locomotor behavior defective,short lived,viable" FBgn0005685 cob cobblestone http://flybase.org/reports/FBgn0005685 - gene - compound eye development ; GO:0048749 | inferred from mutant phenotype - cob - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "eye,ommatidium,eye photoreceptor cell" FBgn0031961 CG7102 - http://flybase.org/reports/FBgn0031961 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 spliceosomal snRNP assembly ; GO:0000387 | inferred from sequence or structural similarity with HGNC:11161 catalytic step 2 spliceosome ; GO:0071013 | inferred from sequence or structural similarity with HGNC:11161 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "CG17973, CG7102" "IPR000210:BTB/POZ domain, IPR006571:TLDc domain, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain" CG7102 11-Aug-17 DroID_v2017_08 - Scer\YIL001W - "Xtro\btbd9, Xtro\btbd19" Mmus\Btbd9 "Hsap\BTBD19, Hsap\BTBD9" viable DRSC03007 K -0.330952588 -0.370821336 -0.482054164 -0.382802781 -1.888000227 -0.290695145 FBgn0039028 CG13840 - http://flybase.org/reports/FBgn0039028 protein_coding_gene - - - CG13840 - CG13840 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028398 Taf10 TBP-associated factor 10 http://flybase.org/reports/FBgn0028398 protein_coding_gene "transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay" transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11543 inferred from sequence or structural similarity with SGD:S000002574 transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11543 inferred from sequence or structural similarity with SGD:S000002574 histone acetyltransferase complex ; GO:0000123 | inferred from sequence or structural similarity with HGNC:11543 inferred from sequence or structural similarity with SGD:S000002574 nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "dTAF[[II]]24, TAF[[II]]24, dmTAF10, dmTaf10, TAF, taf24, TFIID, TAF[[II]], TAF10, CG2859, dtafII24, dTAFII24, TafII24, Taf24, BcDNA:RE73934, Taf10, dTAF10" "IPR003923:Transcription initiation factor TFIID, 23-30kDa subunit" CG2859 11-Aug-17 DroID_v2017_08 Drer\taf10 Scer\TAF10 Cele\taf-10 Xtro\taf10 Mmus\Taf10 Hsap\TAF10 "planar polarity defective,partially lethal - majority die,some die during pupal stage" DRSC30091 K 0.664342779 1.806765162 FBgn0014185 gyn-2 gyn-2 http://flybase.org/reports/FBgn0014185 - gene - - - gyn-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267555 CR45895 - http://flybase.org/reports/FBgn0267555 non_protein_coding_gene - - - CR45895 - CR45895 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267006 CR45450 - http://flybase.org/reports/FBgn0267006 non_protein_coding_gene - - - CR45450 - CR45450 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260098 2L2218 - http://flybase.org/reports/FBgn0260098 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L2218 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0005192 l(2)S55 lethal of Seto 55 http://flybase.org/reports/FBgn0005192 - gene - - - l(2)S55 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0060992 l(3)S027342b lethal (3) S027342b http://flybase.org/reports/FBgn0060992 gene - - - "0273/42, l(3)S027342b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0027496 epsilonCOP Coat Protein (coatomer) epsilon http://flybase.org/reports/FBgn0027496 - protein_coding_gene structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR006822 "ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000086687 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000086687 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000086687" COPI vesicle coat ; GO:0030126 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "BcDNA:LD29885, CG9543, epsilonCOP, bcDNA:LD29885, epsilon-COP, epsilon-Cop" "IPR006822:Coatomer, epsilon subunit, IPR011990:Tetratricopeptide-like helical domain" CG9543 11-Aug-17 DroID_v2017_08 Drer\cope Scer\SEC28 Cele\cope-1 Xtro\cope Mmus\Cope Hsap\COPE viable FBgn0002858 Mst51F Male-specific RNA 51F http://flybase.org/reports/FBgn0002858 - gene - - - "mst-35, mst(2)ag-35, Mst51F" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025004 E(var)3-101 E(var)3-101 http://flybase.org/reports/FBgn0025004 - gene - - - "E-(3)1[01], E(var)3-101" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031990 PAPLA1 Phosphatidic Acid Phospholipase A1 http://flybase.org/reports/FBgn0031990 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR004177 phospholipase activity ; GO:0004620 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype ER to Golgi transport vesicle ; GO:0030134 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG14278, CG8552, Sec23-IP, PAPLA1" "IPR004170:WWE domain, IPR004177:DDHD domain, IPR029058:Alpha/Beta hydrolase fold" CG8552 11-Aug-17 DroID_v2017_08 "Drer\sec23ip, Drer\ddhd2, Drer\ddhd1a, Drer\ddhd1b" "Scer\YOR022C, Scer\FIG2" "Cele\lec-2, Cele\ipla-1" "Xtro\ddhd2, Xtro\sec23ip" "Mmus\Ddhd1, Mmus\Ddhd2, Mmus\Sec23ip" "Hsap\SEC23IP, Hsap\DDHD1, Hsap\DDHD2" "viable,fertile" FBgn0084797 G56 G56 http://flybase.org/reports/FBgn0084797 gene - - - G56 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062636 EP995 EP995 http://flybase.org/reports/FBgn0062636 gene - - - "EP(3)0995, EP995" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260431 CG42526 - http://flybase.org/reports/FBgn0260431 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42526 IPR006578:MADF domain CG42526 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-207i20.3, Drer\LOC100330838, Drer\zgc:152938" - "Cele\madf-8, Cele\madf-10, Cele\madf-2, Cele\madf-3, Cele\madf-9, Cele\madf-4, Cele\madf-5" - - - FBgn0032213 CG5390 - http://flybase.org/reports/FBgn0032213 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" extracellular region ; GO:0005576 | inferred from direct assay "CG5390, c-SPH35, SPH35, gh06341, BEST:GH06341, SPH" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG5390 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\f7" - Cele\try-1 - "Mmus\Klkb1, Mmus\Klk1b5, Mmus\Klk1b11, Mmus\F11, Mmus\Klk1b3, Mmus\Klk1b22, Mmus\Klk1b1, Mmus\Klk1b9, Mmus\Klk1b8, Mmus\Klk11, Mmus\Klk1, Mmus\Klk1b21, Mmus\Klk1b16, Mmus\Klk1b27, Mmus\Egfbp2, Mmus\Klk1b4, Mmus\Klk1b24, Mmus\Klk1b26" "Hsap\KLK11, Hsap\KLK3, Hsap\KLK2, Hsap\F11, Hsap\KLKB1, Hsap\KLK1" viable FBgn0266157 CR44863 - http://flybase.org/reports/FBgn0266157 non_protein_coding_gene - - - CR44863 - CR44863 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023508 Ocrl Oculocerebrorenal syndrome of Lowe http://flybase.org/reports/FBgn0023508 - protein_coding_gene phosphatidylinositol bisphosphate phosphatase activity ; GO:0034593 | inferred from mutant phenotype GTPase activator activity ; GO:0005096 | NOT inferred from key residues GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with HGNC:8108 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype actomyosin contractile ring localization ; GO:0032187 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with HGNC:8108 phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from mutant phenotype regulation of cytokinesis, actomyosin contractile ring assembly ; GO:2000431 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype" early endosome ; GO:0005769 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay "EG:86E4.5, CG3573, ocrl, Ocrl, dOCRL" "IPR000198:Rho GTPase-activating protein domain, IPR000300:Inositol polyphosphate-related phosphatase, IPR005135:Endonuclease/exonuclease/phosphatase, IPR008936:Rho GTPase activation protein, IPR013783:Immunoglobulin-like fold, IPR031896:Type II inositol 1,4,5-trisphosphate 5-phosphatase, PH domain" CG3573 11-Aug-17 DroID_v2017_08 "Drer\inpp5jb, Drer\inpp5ka, Drer\inpp5b, Drer\inpp5kb, Drer\sh2d1aa, Drer\ocrl, Drer\inppl1b, Drer\inpp5d, Drer\inpp5e, Drer\inpp5j, Drer\inppl1a" "Scer\INP52, Scer\INP54, Scer\INP51, Scer\INP53" Cele\ocrl-1 "Xtro\inpp5k, Xtro\inpp5b, Xtro\inpp5d, Xtro\sec16a, Xtro\ocrl, Xtro\inpp5j" "Mmus\Inpp5e, Mmus\Inpp5d, Mmus\Sh2d1b2, Mmus\Inpp5k, Mmus\Inpp5b, Mmus\Ocrl, Mmus\Inpp5j, Mmus\Inppl1, Mmus\Sh2d1b1, Mmus\Sh2d1a" "Hsap\INPP5D, Hsap\OCRL, Hsap\SH2D1B, Hsap\INPP5J, Hsap\INPP5B, Hsap\INPP5E, Hsap\INPP5K, Hsap\INPPL1" "viable,fertile,visible" "chaeta,supernumerary" FBgn0026430 Grip84 Gamma-tubulin ring protein 84 http://flybase.org/reports/FBgn0026430 - protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule minus-end binding ; GO:0051011 | contributes_to inferred from direct assay structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin binding ; GO:0043015 | inferred from direct assay microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype interphase microtubule nucleation by interphase microtubule organizing center ; GO:0051415 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 microtubule nucleation ; GO:0007020 | inferred from direct assay astral microtubule organization ; GO:0030953 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 spermatogenesis ; GO:0007283 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity gamma-tubulin small complex ; GO:0008275 | inferred from direct assay mitotic spindle ; GO:0072686 | colocalizes_with inferred from direct assay centrosome ; GO:0005813 | colocalizes_with inferred from direct assay equatorial microtubule organizing center ; GO:0000923 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin small complex ; GO:0008275 | inferred from physical interaction with Grip91 inferred from physical interaction with γTub23C "Grip84, Dgrip84, Dgrips84, GCP2, CG3917, l(1)[[t]]PG66, l(1)[[t]]PG36, grip84, DGrip84" IPR007259:Gamma-tubulin complex component protein CG3917 11-Aug-17 DroID_v2017_08 "Drer\tubgcp2, Drer\tubgcp3, Drer\tubgcp4" "Scer\SPC97, Scer\SPC98" - "Xtro\tubgcp2, Xtro\tubgcp3, Xtro\tubgcp4" "Mmus\Tubgcp2, Mmus\Tubgcp3, Mmus\Tubgcp4" "Hsap\TUBGCP4, Hsap\TUBGCP3, Hsap\TUBGCP2" embryonic stage "lethal,recessive,mitotic cell cycle defective,partially lethal - majority die,male sterile,meiotic cell cycle defective,viable,visible" "chromosome & procephalic neuroblast | third instar larval stage,spindle & procephalic neuroblast | third instar larval stage,pericentriolar material & procephalic neuroblast | third instar larval stage,macrochaeta & thorax,cuticle & abdomen,nucleus & onion stage spermatid,Nebenkern & onion stage spermatid,nucleus & onion stage spermatid | supernumerary,Nebenkern & onion stage spermatid | supernumerary,pericentriolar material & primary spermatocyte,spindle & primary spermatocyte,aster & primary spermatocyte,trichogen cell" DRSC20248 I 3.925465832 -0.200243084 0.222298365 -0.035259642 -0.087225277 0.584048881 FBgn0261956 baz::par-6 - http://flybase.org/reports/FBgn0261956 engineered_fusion_gene - - - baz::par-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "follicle cell,somatic clone" FBgn0053080 CG33080 - http://flybase.org/reports/FBgn0053080 protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR000322" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000322 - "CG3141, CG15775, CG15774, CG33080" "IPR000322:Glycoside hydrolase family 31, IPR017853:Glycoside hydrolase superfamily" CG33080 11-Aug-17 DroID_v2017_08 "Drer\ganab, Drer\gaa, Drer\si:ch211-236l14.4, Drer\si:ch211-117c19.1, Drer\si:dkey-228b2.5, Drer\si:ch73-12o23.1, Drer\zgc:171967" Scer\ROT2 "Cele\aagr-4, Cele\aagr-3" "Xtro\mgam, Xtro\gaa, Xtro\kiaa1161" "Mmus\AI464131, Mmus\Mgam, Mmus\Gaa, Mmus\Sis, Mmus\Ganab" "Hsap\GANAB, Hsap\MGAM, Hsap\SI, Hsap\MGAM2, Hsap\GAA, Hsap\KIAA1161" "partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,viable" DRSC18285 I -1.507725032 0.564026369 -0.384340044 0.090007679 0.24180156 -0.663448441 FBgn0011118 l(1)Q79 lethal (1) Q79 http://flybase.org/reports/FBgn0011118 FBgn0010210 gene - - - l(1)Q79 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003544 stw straw http://flybase.org/reports/FBgn0003544 - gene - - - "stw, str" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,body color defective,viable,poor,semidominant" "wing,macrochaeta,microchaeta" FBgn0005196 l(3)36d10 lethal (3) 36d10 http://flybase.org/reports/FBgn0005196 - gene - - - l(3)36d10 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265688 CR44495 - http://flybase.org/reports/FBgn0265688 non_protein_coding_gene - - - CR44495 - CR44495 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065962 l(2)SH0030 lethal (2) SH0030 http://flybase.org/reports/FBgn0065962 gene - - - "l(2)SH0030, l(2)SH2 0030" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028109 l(3)S068911 lethal (3) S068911 http://flybase.org/reports/FBgn0028109 gene - - - "0689/11, l(3)S068911" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031413 CG9967 - http://flybase.org/reports/FBgn0031413 protein_coding_gene - - - CG9967 IPR032016:Protein of unknown function DUF4796 CG9967 11-Aug-17 DroID_v2017_08 "Drer\mkrn2os.1, Drer\mkrn2os.2" - "Cele\W10D9.6, Cele\W10D9.3" - Mmus\Mkrn2os Hsap\MKRN2OS viable FBgn0026880 E(Ubx)3L E(Ubx)3L http://flybase.org/reports/FBgn0026880 - gene - - - E(Ubx)3L - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260438 rad201 radiation-resistant 201 http://flybase.org/reports/FBgn0260438 protein_coding_gene - - - "rad(2)201, rad(2)201[G1], rad201" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive,radiation sensitive" "egg chamber,oocyte,egg" FBgn0038892 CG15498 - http://flybase.org/reports/FBgn0038892 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15498 - CG15498 11-Aug-17 DroID_v2017_08 Drer\cfap161 - - Xtro\cfap161 Mmus\Cfap161 Hsap\CFAP161 viable FBgn0032533 CG16888 - http://flybase.org/reports/FBgn0032533 protein_coding_gene - - - CG16888 - CG16888 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264837 CR44045 - http://flybase.org/reports/FBgn0264837 non_protein_coding_gene - - - CR44045 - CR44045 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052846 CG32846 - http://flybase.org/reports/FBgn0052846 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32846 - CG32846 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029909 mAChR-C "muscarinic Acetylcholine Receptor, C-type" http://flybase.org/reports/FBgn0029909 protein_coding_gene "G-protein coupled acetylcholine receptor activity ; GO:0016907 | inferred from direct assay dopamine neurotransmitter receptor activity, coupled via Gs ; GO:0001588 | inferred from biological aspect of ancestor with PANTHER:PTN001205456 G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity" G-protein coupled acetylcholine receptor signaling pathway ; GO:0007213 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0016907" "CG12796, mAChR-C" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG12796 11-Aug-17 DroID_v2017_08 Drer\htr6 - "Cele\F57C9.6, Cele\C01F1.4, Cele\F59D12.1, Cele\F36D4.4, Cele\tyra-2" - "Mmus\Gpr119, Mmus\Chrm3, Mmus\Gpr12" "Hsap\GPR12, Hsap\GPR119, Hsap\CHRM3" viable FBgn0058158 CG40158 - http://flybase.org/reports/FBgn0058158 protein_coding_gene - - - CG40158 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266818 CR45280 - http://flybase.org/reports/FBgn0266818 non_protein_coding_gene - - - CR45280 - CR45280 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069301 XRCC4 XRCC4 http://flybase.org/reports/FBgn0069301 gene protein binding ; GO:0005515 | inferred from physical interaction with Lig4 - - XRCC4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085551 CG40995 - http://flybase.org/reports/FBgn0085551 protein_coding_gene - - - CG40995 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060547 l(3)S098614 lethal (3) S098614 http://flybase.org/reports/FBgn0060547 gene - - - "0986/14, l(3)S098614" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266806 CR45268 - http://flybase.org/reports/FBgn0266806 non_protein_coding_gene - - - CR45268 - CR45268 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004984 blu blunt http://flybase.org/reports/FBgn0004984 - gene - - - blu - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0038330 CG14868 - http://flybase.org/reports/FBgn0038330 protein_coding_gene - - - CG14868 IPR019179:Coiled-coil domain-containing protein 149-A CG14868 11-Aug-17 DroID_v2017_08 "Drer\ccdc149a, Drer\ccdc149b" - Cele\ccdc-149 Xtro\ccdc149 Mmus\Ccdc149 Hsap\CCDC149 DRSC14991 I 1.010259923 1.533437542 0.94208393 0.962579695 -0.118877228 0.478200638 FBgn0002797 ms(1)7 male sterile (1) 7 http://flybase.org/reports/FBgn0002797 - gene - - - ms(1)7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile,viable" FBgn0259564 B0578 - http://flybase.org/reports/FBgn0259564 gene - - - B0578 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025827 CG6421 - http://flybase.org/reports/FBgn0025827 FBgn0034163 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR008597 - - "EG:EG0003.8, CG6421" "IPR008597:Destabilase, IPR023346:Lysozyme-like domain" CG6421 11-Aug-17 DroID_v2017_08 - - "Cele\ilys-4, Cele\ilys-1, Cele\ilys-5, Cele\ilys-2, Cele\ilys-3, Cele\ilys-6" - - - viable FBgn0017376 l(1)HM452 lethal (1) HM452 http://flybase.org/reports/FBgn0017376 - gene - - - l(1)HM452 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038123 CG8508 - http://flybase.org/reports/FBgn0038123 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.216, CG8508" - CG8508 11-Aug-17 DroID_v2017_08 "Drer\ovgp1, Drer\chia.5, Drer\si:ch211-226m16.2, Drer\chia.2" Scer\CTS2 - "Xtro\chia, Xtro\chit1, Xtro\LOC548945, Xtro\ctbs" "Mmus\Chil1, Mmus\Ovgp1, Mmus\Chil3, Mmus\Chia1, Mmus\Ctbs, Mmus\Chit1, Mmus\Chil5, Mmus\Chil6, Mmus\Chil4" "Hsap\CHI3L1, Hsap\CHI3L2, Hsap\CHIT1, Hsap\OVGP1, Hsap\CHIA" viable FBgn0004522 l(4)102CDf lethal (4) 102CDf http://flybase.org/reports/FBgn0004522 - gene - - - "l(4)CDf, l(4)7, l(4)102CDf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0013295 M(2)OE227 M(2)OE227 http://flybase.org/reports/FBgn0013295 - gene - - - M(2)OE227 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001468 l(1)8 lethal (1) 8 http://flybase.org/reports/FBgn0001468 - gene - - - "tsl(1)8, l(1)8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,heat sensitive,lethal,male" "spermatid,primary spermatocyte cyst,spermatocyte" FBgn0264565 CR43937 - http://flybase.org/reports/FBgn0264565 non_protein_coding_gene - - - CR43937 - CR43937 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039801 Npc2h Niemann-Pick type C-2h http://flybase.org/reports/FBgn0039801 protein_coding_gene lipid antigen binding ; GO:0030882 | inferred from direct assay lipoteichoic acid binding ; GO:0070891 | inferred from direct assay lipopolysaccharide binding ; GO:0001530 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from direct assay sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 intracellular cholesterol transport ; GO:0032367 | inferred from electronic annotation with InterPro:IPR033916 hemolymph coagulation ; GO:0042381 | inferred from expression pattern sterol transport ; GO:0015918 | inferred from sequence or structural similarity with Npc2a extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "DmML1A, BcDNA:RH68460, BcDNA:RH04252, BcDNA:GH26608, npc2h, Npc2h, CG11315" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set, IPR033916:ML domain, Npc2 like" CG11315 11-Aug-17 DroID_v2017_08 "Drer\npc2, Drer\zgc:193725" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 viable FBgn0036660 CG13025 - http://flybase.org/reports/FBgn0036660 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:25539 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:25539 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:25539 CG13025 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13025 11-Aug-17 DroID_v2017_08 Drer\rfwd3 - Cele\ZC13.1 Xtro\rfwd3 Mmus\Rfwd3 Hsap\RFWD3 "viable,fertile" FBgn0053728 snmRNA:430:CR33728 snmRNA:430:CR33728 http://flybase.org/reports/FBgn0053728 non_protein_coding_gene - - - "CR33728, snmRNA:430:CR33728" - CR33728 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063374 snoRNA:snR38:54Eb snoRNA:snR38:54Eb http://flybase.org/reports/FBgn0063374 snoRNA_gene - - - "Snr38snoRNA, CR32896, snoRNA:snR38:54Eb" - CR32896 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039711 CG7824 - http://flybase.org/reports/FBgn0039711 protein_coding_gene - - - CG7824 IPR031961:Domain of unknown function DUF4780 CG7824 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265452 CR44352 - http://flybase.org/reports/FBgn0265452 non_protein_coding_gene - - - "CR44352, lincRNA.83" - CR44352 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002420 l(3)DTS8 lethal (3) DTS8 http://flybase.org/reports/FBgn0002420 - gene - - - "DTS-8, l(3)DTS8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,lethal - all die before end of larval stage,some die during larval stage" FBgn0015987 l(2)PC4-Q lethal (2) PC4-Q http://flybase.org/reports/FBgn0015987 - gene - - - l(2)PC4-Q - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015699 E(var)8 Enhancer of variegation 8 http://flybase.org/reports/FBgn0015699 - gene - - - E(var)8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0035415 CG14966 - http://flybase.org/reports/FBgn0035415 protein_coding_gene - - - CG14966 IPR003746:Protein of unknown function DUF167 CG14966 11-Aug-17 DroID_v2017_08 Drer\zgc:193812 - Cele\W01A8.2 Xtro\c15orf40 Mmus\3110040N11Rik Hsap\C15orf40 viable FBgn0031878 sip2 septin interacting protein 2 http://flybase.org/reports/FBgn0031878 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sep1 inferred from physical interaction with Sep2 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG9188, sip2" - CG9188 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002425 l(3)F24 lethal (3) F24 http://flybase.org/reports/FBgn0002425 - gene - - - "l(3)24, l(3)F24" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone,wing hair" FBgn0004492 DhpO Dihydropterin oxidase http://flybase.org/reports/FBgn0004492 - gene dihydropterin oxidase activity ; GO:0004154 | inferred from direct assay dihydropteridine metabolic process ; GO:0051067 | inferred from direct assay - DhpO - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035208 CG9184 - http://flybase.org/reports/FBgn0035208 protein_coding_gene - - - CG9184 - CG9184 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08636 E 0.879868527 1.027657362 1.746869918 1.431078397 0.604011885 -0.022614165 FBgn0267709 CR46042 - http://flybase.org/reports/FBgn0267709 non_protein_coding_gene - - - CR46042 - CR46042 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052539 CG32539 - http://flybase.org/reports/FBgn0052539 protein_coding_gene - - - CG32539 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063645 CE3-1 "Calcineurin enhancer, chromosome 3, group 1" http://flybase.org/reports/FBgn0063645 gene - - - CE3-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013319 Pcp25 Pupal-cuticle-protein-25kD http://flybase.org/reports/FBgn0013319 - gene - - - Pcp25 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005068 fs(2)OW209 female sterile (2) OW209 http://flybase.org/reports/FBgn0005068 - gene - - - fs(2)OW209 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065510 l(2)SH1177 lethal (2) SH1177 http://flybase.org/reports/FBgn0065510 gene - - - l(2)SH1177 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262383 mir-284 mir-284 stem loop http://flybase.org/reports/FBgn0262383 miRNA_gene - - - "dme-mir-284, mir-284, miR-284, CR42906, CR33600, dme-miR-284, MiR-284" - CR42906 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal - all die before end of larval stage,some die during larval stage" wing FBgn0069163 mcl(3)Z1641 mcl(3)Z1641 http://flybase.org/reports/FBgn0069163 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1641 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0021894 l(2)k13116 lethal (2) k13116 http://flybase.org/reports/FBgn0021894 - gene - - - l(2)k13116 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037550 CG9667 - http://flybase.org/reports/FBgn0037550 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:29201 first spliceosomal transesterification activity ; GO:0000384 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000314659 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA 3'-splice site recognition ; GO:0000389 | inferred from biological aspect of ancestor with PANTHER:PTN000314659 generation of catalytic spliceosome for second transesterification step ; GO:0000350 | inferred from biological aspect of ancestor with PANTHER:PTN000314659" precatalytic spliceosome ; GO:0071011 | inferred from direct assay post-mRNA release spliceosomal complex ; GO:0071014 | inferred from biological aspect of ancestor with PANTHER:PTN000314659 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay post-spliceosomal complex ; GO:0071020 | inferred from biological aspect of ancestor with PANTHER:PTN000314659 catalytic step 1 spliceosome ; GO:0071012 | inferred from biological aspect of ancestor with PANTHER:PTN000314659 Prp19 complex ; GO:0000974 | inferred from direct assay "CG9667, ISY1" IPR009360:Pre-mRNA-splicing factor Isy1 CG9667 11-Aug-17 DroID_v2017_08 "Drer\isy1, Drer\cdk4" Scer\ISY1 Cele\F53B7.3 Xtro\isy1 Mmus\Isy1 "Hsap\ISY1, Hsap\ISY1-RAB43, Hsap\RAB43" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC16535 I -0.087595313 2.574076219 1.099386934 0.353109175 -0.334236746 0.178483692 FBgn0265101 Sgt1 suppressor-of-G2-allele-of-skp1 http://flybase.org/reports/FBgn0265101 protein_coding_gene "protein binding, bridging ; GO:0030674 | inferred from sequence or structural similarity with SGD:S000005583 chaperone binding ; GO:0051087 | inferred from sequence or structural similarity with SGD:S000005583" centrosome organization ; GO:0051297 | inferred from mutant phenotype maintenance of neuroblast polarity ; GO:0045201 | inferred from direct assay neuroblast proliferation ; GO:0007405 | inferred from direct assay protein stabilization ; GO:0050821 | inferred from mutant phenotype cleavage furrow ; GO:0032154 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "sgt1, Sgt1, CG9617, l(3)s2383, DmSgt1, Q9VHT3" "IPR007052:CS domain, IPR007699:SGS domain, IPR008978:HSP20-like chaperone" CG9617 11-Aug-17 DroID_v2017_08 "Drer\cacybp, Drer\sgut1" Scer\SGT1 Cele\D1054.3 "Xtro\sugt1, Xtro\cacybp" "Mmus\Chordc1, Mmus\Cacybp, Mmus\Sugt1" "Hsap\CHORDC1, Hsap\SUGT1" FBgn0065731 l(2)SH0553 lethal (2) SH0553 http://flybase.org/reports/FBgn0065731 gene - - - "l(2)SH0553, l(2)SH2 0553" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002049 l(2)37Fb lethal (2) 37Fb http://flybase.org/reports/FBgn0002049 - gene - - - "l(2)E146, l(2)37Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261738 EC3322 - http://flybase.org/reports/FBgn0261738 gene - - - EC3322 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0033945 CG12868 - http://flybase.org/reports/FBgn0033945 protein_coding_gene - - - "CT32008, CG12868" - CG12868 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0062517 CG16984 - http://flybase.org/reports/FBgn0062517 protein_coding_gene calmodulin binding ; GO:0005516 | inferred from sequence or structural similarity with MGI:MGI:1918483 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT01695, CG16984" "IPR027012:Enkurin domain, IPR026150:Enkurin" CG16984 11-Aug-17 DroID_v2017_08 Drer\enkur - - Xtro\enkur Mmus\Enkur Hsap\ENKUR FBgn0260805 EP3-612 - http://flybase.org/reports/FBgn0260805 gene - - - EP3-612 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000515 dvw divergent wings http://flybase.org/reports/FBgn0000515 - gene - - - dvw - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male,wild-type,female,male limited,recessive" "wing,macrochaeta" FBgn0065225 l(2)SH2211 lethal (2) SH2211 http://flybase.org/reports/FBgn0065225 gene - - - "l(2)SH2211, l(2)SH2 2211" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024598 spi::vn spi::vn http://flybase.org/reports/FBgn0024598 - engineered_fusion_gene - - - "spi::vn, VN::SPI" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing vein,ectopic,eye,border follicle cell,somatic clone" FBgn0024677 l(1)LefEM7 lethal (1) LefEM7 http://flybase.org/reports/FBgn0024677 - gene - - - "EM7, l(1)LefEM7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263232 Nxf3 Nuclear export factor 3 http://flybase.org/reports/FBgn0263232 protein_coding_gene - poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from biological aspect of ancestor with PANTHER:PTN000070434 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000070434 "Nxf3, CG32135, NXF3, nxf3" "IPR030217:Nuclear RNA export factor, IPR032675:Leucine-rich repeat domain, L domain-like, IPR032710:NTF2-like domain, IPR001611:Leucine-rich repeat, IPR018222:Nuclear transport factor 2, eukaryote, IPR002075:Nuclear transport factor 2" CG32135 11-Aug-17 DroID_v2017_08 "Drer\nxf1, Drer\zgc:153681" Scer\MEX67 "Cele\nxf-1, Cele\nxf-2" Xtro\nxf1 "Mmus\Nxf2, Mmus\Tmem223, Mmus\Nxf1, Mmus\Nxf3, Mmus\Nxf7" "Hsap\NXF5, Hsap\NXF1, Hsap\NXF2, Hsap\NXF3, Hsap\NXF2B" FBgn0001635 l(1)dn15 lethal (1) discs normal 15 http://flybase.org/reports/FBgn0001635 - gene - - - "l(1)d norm-15, l(1)d.norm.-15, l(1)dn15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0022364 Pt-8 Larval protein-8 http://flybase.org/reports/FBgn0022364 - gene - - - Pt-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040370 CG13375 - http://flybase.org/reports/FBgn0040370 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available "EG:BACR37P7.8, CG13375" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG13375 11-Aug-17 DroID_v2017_08 "Drer\diras1b, Drer\kras, Drer\diras2, Drer\si:dkey-27j5.5, Drer\gem, Drer\zgc:171704, Drer\diras1a, Drer\ralab, Drer\hrasb, Drer\rasl12, Drer\rrad, Drer\rergla, Drer\rasl11b, Drer\rsg1, Drer\zgc:153845, Drer\hrasa, Drer\zgc:110699, Drer\LOC100332969, Drer\rit1, Drer\zgc:152698, Drer\ralba, Drer\mras, Drer\si:dkeyp-59c12.1, Drer\rerglb, Drer\ralbb, Drer\rhebl1, Drer\rap1ab, Drer\rap1aa, Drer\rap2c, Drer\ralaa, Drer\rem2, Drer\rasd1, Drer\rras2, Drer\zgc:64022, Drer\rap2ab, Drer\rasl10a, Drer\rheb, Drer\si:ch73-116o1.2, Drer\rap2b, Drer\rem1, Drer\rasl11a, Drer\rras, Drer\nras, Drer\zgc:114118" "Scer\RAS1, Scer\RAS2, Scer\RSR1, Scer\RHB1" "Cele\ssr-2, Cele\D1081.4" "Xtro\gem, Xtro\diras2, Xtro\kras, Xtro\rem2, Xtro\rap2b, Xtro\rasd1, Xtro\LOC733456, Xtro\rem1, Xtro\rasl10a, Xtro\rap2a, Xtro\rap2c, Xtro\rit1, Xtro\rhebl1, Xtro\nras, Xtro\ras-dva, Xtro\rerg, Xtro\diras1, Xtro\rala, Xtro\rergl, Xtro\rasd2, Xtro\rheb, Xtro\hras, Xtro\rsg1, Xtro\rrad, Xtro\ralb, Xtro\rap1b, Xtro\rap1a, Xtro\diras3, Xtro\rasl11b" "Mmus\Rap1a, Mmus\Diras2, Mmus\Rap1b, Mmus\Gem, Mmus\Rasl10a, Mmus\Rheb, Mmus\Rrad, Mmus\Rasl12, Mmus\Gm266, Mmus\Eras, Mmus\Rasd2, Mmus\Mras, Mmus\Rergl, Mmus\Rasd1, Mmus\Rem2, Mmus\Rerg, Mmus\Rhebl1, Mmus\Rras, Mmus\Rasl11b, Mmus\Rap2c, Mmus\Rit2, Mmus\Rsg1, Mmus\Ralb, Mmus\Rem1, Mmus\Hras, Mmus\Diras1, Mmus\Nras, Mmus\Rasl11a, Mmus\Rasl10b, Mmus\Rit1, Mmus\Rap2a, Mmus\Rap2b, Mmus\Rras2, Mmus\Rala, Mmus\Kras" "Hsap\RHEBL1, Hsap\KRAS, Hsap\DIRAS1, Hsap\RERGL, Hsap\MRAS, Hsap\RRAS, Hsap\DIRAS2, Hsap\DIRAS3, Hsap\RRAD, Hsap\RAP2B, Hsap\RASL10B, Hsap\RASD2, Hsap\RASL12, Hsap\RAP2A, Hsap\RAP1A, Hsap\RASL11A, Hsap\RIT2, Hsap\RASL11B, Hsap\RHEB, Hsap\REM2, Hsap\HRAS, Hsap\RERG, Hsap\GEM, Hsap\NRAS, Hsap\RALB, Hsap\RALA, Hsap\RRAS2, Hsap\REM1, Hsap\RIT1, Hsap\RASD1, Hsap\RASL10A, Hsap\RAP1B, Hsap\RAP2C, Hsap\RSG1, Hsap\ERAS" viable FBgn0036590 CG13065 - http://flybase.org/reports/FBgn0036590 protein_coding_gene - - - "BcDNA:RH56745, CG13065" - CG13065 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" DRSC09948 E 0.468574293 0.050841571 1.727710267 -0.831450725 -0.065332039 0.04374212 FBgn0036551 CG17029 - http://flybase.org/reports/FBgn0036551 protein_coding_gene inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from sequence or structural similarity with HGNC:6051 inositol monophosphate 1-phosphatase activity ; GO:0008934 | non-traceable author statement "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550, InterPro:IPR020552 inositol metabolic process ; GO:0006020 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol phosphate dephosphorylation ; GO:0046855 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol phosphate dephosphorylation ; GO:0046855 | inferred from sequence or structural similarity with HGNC:6051 dephosphorylation ; GO:0016311 | non-traceable author statement" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6051 "IMP, CG17029" "IPR000760:Inositol monophosphatase-like, IPR033942:Inositol monophosphatase, IPR020550:Inositol monophosphatase, conserved site, IPR020552:Inositol monophosphatase, Lithium-sensitive, IPR020583:Inositol monophosphatase, metal-binding site" CG17029 11-Aug-17 DroID_v2017_08 "Drer\impa2, Drer\impa1" "Scer\INM1, Scer\INM2" Cele\ttx-7 "Xtro\impa2, Xtro\impa1" "Mmus\Impa1, Mmus\Impa2" "Hsap\IMPA2, Hsap\IMPA1" viable FBgn0085650 CG41489 - http://flybase.org/reports/FBgn0085650 protein_coding_gene - - - CG41489 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034138 RpS15 Ribosomal protein S15 http://flybase.org/reports/FBgn0034138 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR002222, InterPro:IPR005713, InterPro:IPR023575 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR020934 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002222, InterPro:IPR005713, InterPro:IPR023575 cytoplasmic translation ; GO:0002181 | traceable author statement ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000222938" small ribosomal subunit ; GO:0015935 | inferred from electronic annotation with InterPro:IPR005713 cytoplasm ; GO:0005737 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement nucleolus ; GO:0005730 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay "CG8332, anon-EST:Posey185, anon-EST:Posey137, RpS15, s15, S15" "IPR002222:Ribosomal protein S19/S15, IPR005713:Ribosomal protein S19A/S15e, IPR023575:Ribosomal protein S19, superfamily, IPR020934:Ribosomal protein S19 conserved site" CG8332 11-Aug-17 DroID_v2017_08 Drer\rps15 "Scer\RPS15, Scer\RSM19" Cele\rps-15 Xtro\rps15 Mmus\Rps15 Hsap\RPS15 lethal DRSC07151 EK -0.624074692 -0.792128335 -2.281032805 -3.803663871 1.896970021 3.03628177 FBgn0033138 Tsp42Eq Tetraspanin 42Eq http://flybase.org/reports/FBgn0033138 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model "CG12832, Dm.Tsp42Eq, Tsp42Eq" "IPR008952:Tetraspanin, EC2 domain, IPR018499:Tetraspanin/Peripherin" CG12832 11-Aug-17 DroID_v2017_08 Drer\cd63 - "Cele\tsp-1, Cele\tsp-14, Cele\tsp-5, Cele\tsp-7, Cele\tsp-2, Cele\tsp-3" Xtro\cd63 Mmus\Cd63 Hsap\CD63 "viable,fertile" FBgn0260030 22F2 - http://flybase.org/reports/FBgn0260030 gene - - - 22F2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0259663 B0969 - http://flybase.org/reports/FBgn0259663 gene - - - B0969 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0060961 l(3)S032401b lethal (3) S032401b http://flybase.org/reports/FBgn0060961 gene - - - "0324/01, l(3)S032401b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001534 l(1)14Ab lethal (1) 14Ab http://flybase.org/reports/FBgn0001534 - gene - - - "h5c, l(1)14Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015477 Rme-8 Receptor mediated endocytosis 8 http://flybase.org/reports/FBgn0015477 FBgn0033390 protein_coding_gene - receptor-mediated endocytosis ; GO:0006898 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG8014, l(2)45Ba, E(shi)2-1, Rme-8, rme-8" "IPR025640:Domain of unknown function DUF4339, IPR001623:DnaJ domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR011993:PH domain-like" CG8014 11-Aug-17 DroID_v2017_08 - - Cele\rme-8 Xtro\dnajc13 Mmus\Dnajc13 Hsap\DNAJC13 "lethal - all die before end of larval stage,recessive,some die during larval stage,cell size defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "border follicle cell,somatic clone,garland cell & endosome,eye photoreceptor cell,rhabdomere,ommatidium,endosome & garland cell | somatic clone,trichogen cell" FBgn0030051 spirit Serine Protease Immune Response Integrator http://flybase.org/reports/FBgn0030051 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred by curator from GO:0050832 "SP33, c-SP33, spirit, CG2056, Spirit" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site, IPR022700:Proteinase, regulatory CLIP domain" CG2056 11-Aug-17 DroID_v2017_08 - - Cele\try-3 - - - "immune response defective,viable" FBgn0040822 CG14150 - http://flybase.org/reports/FBgn0040822 protein_coding_gene - - - CG14150 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051044 CR31044 - http://flybase.org/reports/FBgn0051044 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD09455, CG31044, CR31044, pri-mir-279_mir-996" - CR31044 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "mushroom body & axon7B,Kenyon cell,adult mushroom body,embryonic/larval hemocyte | third instar larval stage" FBgn0003551 su(Cbx) suppressor of Contrabithorax http://flybase.org/reports/FBgn0003551 FBgn0003552 gene - - - su(Cbx) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019640 Antp::ftz Antp::ftz http://flybase.org/reports/FBgn0019640 - engineered_fusion_gene - - - Antp::ftz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266783 CR45248 - http://flybase.org/reports/FBgn0266783 non_protein_coding_gene - - - CR45248 - CR45248 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026644 l(2)k06131 lethal (2) k06131 http://flybase.org/reports/FBgn0026644 - gene - - - l(2)k06131 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033741 CG8545 - http://flybase.org/reports/FBgn0033741 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR011023, InterPro:IPR018314 rRNA (cytosine-C5-)-methyltransferase activity ; GO:0009383 | inferred from biological aspect of ancestor with PANTHER:PTN000515974" maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000515974 rRNA base methylation ; GO:0070475 | inferred from biological aspect of ancestor with PANTHER:PTN000515974 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000515974 "CG8545, Nol1Nt" "IPR001678:SAM-dependent methyltransferase RsmB/NOP2-type, IPR011023:Nop2p, IPR018314:Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR023267:RNA (C5-cytosine) methyltransferase, IPR023273:RNA (C5-cytosine) methyltransferase, NOP2, IPR031341:Ribosomal RNA small subunit methyltransferase F, N-terminal" CG8545 11-Aug-17 DroID_v2017_08 "Drer\nop2, Drer\nsun6" Scer\NOP2 Cele\nol-1 "Xtro\nsun6, Xtro\nop2" "Mmus\Nop2, Mmus\Nsun6" "Hsap\NOP2, Hsap\NSUN6" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014212 l(2)31Ab lethal (2) 31Ab http://flybase.org/reports/FBgn0014212 - gene - - - l(2)31Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026136 CkIIbeta2 Casein kinase II beta2 subunit http://flybase.org/reports/FBgn0026136 - protein_coding_gene "protein kinase regulator activity ; GO:0019887 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150" protein phosphorylation ; GO:0006468 | non-traceable author statement "protein kinase CK2 complex ; GO:0005956 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150" "CK2, CKIIbeta', CK2beta', DmCKIIbeta', CKIIb2, CG8914, CkIIbeta2, DmCK2beta', dCK2beta', CKIIbeta2, Dm-CK2-beta'" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG8914 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B "lethal,viable" FBgn0000532 E111 E111 http://flybase.org/reports/FBgn0000532 - gene - - - E111 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040071 tara taranis http://flybase.org/reports/FBgn0040071 protein_coding_gene - "lateral inhibition ; GO:0046331 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from genetic interaction with brm inferred from genetic interaction with tna inferred from genetic interaction with osa chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from genetic interaction with brm inferred from genetic interaction with Pc inferred from genetic interaction with trx inferred from genetic interaction with ph-p inferred from genetic interaction with pb inferred from genetic interaction with osa sleep ; GO:0030431 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype" - "CG6889, l(3)jlC5, EP(3)3463, l(3)03881, 5472, l(3)j1C5, anon-WO0257455.25, tara, Tara" "IPR009263:SERTA domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG6889 11-Aug-17 DroID_v2017_08 "Drer\sertad2b, Drer\sertad2a, Drer\si:dkey-177p2.6, Drer\cdca4" - - - "Mmus\Sertad2, Mmus\Sertad1, Mmus\Cdca4" "Hsap\SERTAD2, Hsap\SERTAD1, Hsap\CDCA4" "learning defective,viable,lethal,fertile,partially lethal - majority live,visible,recessive,dominant,wild-type,poor,body color defective" "wing,posterior compartment,macrochaeta,wing vein L5,adult abdominal sensillum,ectopic,scutellar bristle,trichogen cell,tormogen cell,arista,haltere,wing vein,eye,chaeta,supernumerary,mesothoracic tergum" FBgn0065911 l(2)SH0180 lethal (2) SH0180 http://flybase.org/reports/FBgn0065911 gene - - - l(2)SH0180 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022087 l(2)k07406 lethal (2) k07406 http://flybase.net/reports/FBgn0022087.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive,partially lethal" FBgn0005233 l(3)R33 lethal of Roberts 33 http://flybase.org/reports/FBgn0005233 - gene - - - "l(3)B33, l(3)R33" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0069400 KH5 KH5 http://flybase.org/reports/FBgn0069400 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available KH5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012000 tRNA:Val-CAC-2-3 transfer RNA:Valine-CAC 2-3 http://flybase.org/reports/FBgn0012000 "FBgn0003853, FBgn0011997, FBgn0051500, FBgn0060025" tRNA_gene GUG codon-amino acid adaptor activity ; GO:0033452 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033452 cytosol ; GO:0005829 | inferred by curator from GO:0033452 "CR31500, valine tRNA, tRNA[Val][[3b]], Val-3b, AE002699.trna2-ValCAC, tRNA:V3b, tRNA:V:CAC:AE002699-b, tRNA:val3b:84Dc, chr3R.trna75-ValCAC, tRNA:Val-CAC-2-3, tRNA:V3b:84Dc, tRNA-Val-CAC-2-3, GUG" - CR31500 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264751 Vti1b Vesicle transport through interaction with t-SNAREs 1b http://flybase.org/reports/FBgn0264751 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence model vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with SGD:S000004810 vesicle-mediated transport ; GO:0016192 | inferred from sequence model SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with RGD:1560475 SNARE complex ; GO:0031201 | inferred from sequence model Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:17793 "Vti1b, CG44009, CG7682, CG31232, EP(3)1037" IPR000727:Target SNARE coiled-coil homology domain CG44009 11-Aug-17 DroID_v2017_08 "Drer\ccnt1, Drer\ccnk, Drer\vti1b, Drer\fam58a, Drer\ccnt2a, Drer\ccnt2b" "Scer\VTI1, Scer\CTK2" - "Xtro\ccnt1, Xtro\ccnt2, Xtro\ccnk, Xtro\vti1b, Xtro\fam58a" "Mmus\Ccnt2, Mmus\Ccnk, Mmus\Vti1b, Mmus\Ccnt1, Mmus\Fam58b" "Hsap\CCNT2, Hsap\CCNK, Hsap\VTI1B, Hsap\CCNT1, Hsap\FAM58A" "viable,fertile" FBgn0030185 CG15310 - http://flybase.org/reports/FBgn0030185 protein_coding_gene - - - CG15310 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020799 ni-s nicked-similis http://flybase.org/reports/FBgn0020799 - gene - - - ni-s - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000592 Est-6 Esterase 6 http://flybase.org/reports/FBgn0000592 FBgn0017620 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay "ovulation ; GO:0030728 | traceable author statement sperm storage ; GO:0046693 | traceable author statement sperm competition ; GO:0046692 | NOT traceable author statement regulation of female receptivity, post-mating ; GO:0046008 | traceable author statement pheromone biosynthetic process ; GO:0042811 | inferred from direct assay inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern regulation of oviposition ; GO:0046662 | traceable author statement courtship behavior ; GO:0007619 | inferred from mutant phenotype mating ; GO:0007618 | traceable author statement" extracellular space ; GO:0005615 | inferred from direct assay "EST-6, Est6, CG6917, EST-5, est-6, EST6, Est, est6, Est-5, Est-D, Est-6, Est-5B, Est 6" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG6917 11-Aug-17 DroID_v2017_08 "Drer\nlgn2b, Drer\ces2, Drer\nlgn3a, Drer\cel.1, Drer\cell, Drer\nlgn4a, Drer\nlgn1, Drer\nlgn3b, Drer\nlgn4b, Drer\nlgn2a, Drer\si:ch211-93f2.1, Drer\ces3" - "Cele\F15A8.6, Cele\T07H6.1, Cele\F07C4.12, Cele\Y71H2AM.13, Cele\C52A10.2, Cele\B0238.1, Cele\T28C12.4, Cele\K11G9.2, Cele\R173.3, Cele\K07C11.4, Cele\K11G9.1, Cele\C52A10.1, Cele\F56C11.6, Cele\K11G9.3, Cele\F13H6.3, Cele\ges-1, Cele\T28C12.5" "Xtro\LOC100494782, Xtro\nlgn4x, Xtro\nlgn3, Xtro\ces2, Xtro\nlgn2, Xtro\cel, Xtro\ces3" "Mmus\Ces1d, Mmus\Ces4a, Mmus\Ces1c, Mmus\Nlgn1, Mmus\Ces2b, Mmus\Ces1e, Mmus\Ces2a, Mmus\Cel, Mmus\Ces3a, Mmus\Ces2g, Mmus\Nlgn2, Mmus\Ces1h, Mmus\Ces5a, Mmus\Ces3b, Mmus\Ces2e, Mmus\Ces2h, Mmus\Ces2f, Mmus\Ces1f, Mmus\Ces1b, Mmus\Nlgn3, Mmus\Ces1g, Mmus\Ces2c" "Hsap\NLGN1, Hsap\CES2, Hsap\NLGN4X, Hsap\CES5A, Hsap\CES1, Hsap\NLGN2, Hsap\CES3, Hsap\CES4A, Hsap\NLGN3, Hsap\CEL, Hsap\NLGN4Y" " adult stage | male , embryonic stage -- adult stage , pupal stage--adult stage " "electrophoretic variant,fast,slow,partially lethal - majority die,some die during pupal stage" FBgn0000545 Extra-combs Extra combs http://flybase.org/reports/FBgn0000545 - gene - - - "Eco, Extra-combs" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002241 l(3)68Cc lethal (3) 68Cc http://flybase.org/reports/FBgn0002241 - gene - - - "l(3)C70, l(3)68Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal" "wing,macrochaeta" FBgn0042098 CG18735 - http://flybase.org/reports/FBgn0042098 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP22, CG18735" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG18735 11-Aug-17 DroID_v2017_08 "Drer\prss60.2, Drer\si:dkey-16l2.17, Drer\try, Drer\ovch1, Drer\prss56, Drer\cfd, Drer\zgc:112038, Drer\si:dkeyp-93a5.3, Drer\zgc:92590, Drer\zgc:92511, Drer\gzm3, Drer\si:ch211-165b19.9, Drer\tmprss15, Drer\zgc:153968, Drer\tmprss4a, Drer\gzmk, Drer\tmprss4b, Drer\ela3l, Drer\ctrb1, Drer\zgc:171592, Drer\si:dkey-57c15.4, Drer\ela2, Drer\si:ch211-165b19.5, Drer\zgc:123295, Drer\zgc:92313, Drer\si:ch211-165b19.8, Drer\zgc:163079, Drer\ela2l, Drer\prss60.1, Drer\LOC100004427, Drer\si:dkeyp-93a5.2, Drer\zgc:165423, Drer\ctrl, Drer\zgc:154142, Drer\zgc:92041, Drer\zmp:0000001114, Drer\gzma, Drer\zgc:92745, Drer\mst1, Drer\zgc:112302, Drer\pamr1, Drer\si:dkey-238d18.3, Drer\LOC562139, Drer\zgc:112160, Drer\prss60.3, Drer\zgc:112285, Drer\zgc:112368" - "Cele\try-6, Cele\try-1, Cele\svh-1" "Xtro\cela2a, Xtro\cela3a, Xtro\ctrb1, Xtro\mst1, Xtro\ctrb2, Xtro\LOC100135144, Xtro\prss29" "Mmus\Tmprss11b, Mmus\Tmprss11a, Mmus\Tmprss11g, Mmus\Klk15, Mmus\Hgf, Mmus\Prss33, Mmus\Tmprss11c, Mmus\Cela3b, Mmus\Prss30, Mmus\Try10, Mmus\Gm5771, Mmus\Ctrb1, Mmus\Prss34, Mmus\Prss3, Mmus\Tmprss11d, Mmus\Cela3a, Mmus\Prss1, Mmus\Prss2, Mmus\Ctrl, Mmus\Cela2a, Mmus\Tmprss11e, Mmus\Gm10334, Mmus\Klk9, Mmus\Tmprss4, Mmus\Try4, Mmus\2210010C04Rik, Mmus\Tmprss11f, Mmus\Cela1, Mmus\Tmprss2, Mmus\Mst1, Mmus\St14, Mmus\Ctrc" "Hsap\PRSS1, Hsap\CELA3A, Hsap\TMPRSS4, Hsap\PRSS3, Hsap\ST14, Hsap\CTRB1, Hsap\MST1, Hsap\HPN, Hsap\MST1L, Hsap\CTRL, Hsap\PRSS33, Hsap\KLK9, Hsap\CTRB2, Hsap\TMPRSS5, Hsap\TMPRSS3, Hsap\CELA2B, Hsap\CELA1, Hsap\TMPRSS2, Hsap\KLK15, Hsap\HGF, Hsap\CELA2A, Hsap\CTRC, Hsap\CELA3B" viable FBgn0263381 CR43433 - http://flybase.org/reports/FBgn0263381 non_protein_coding_gene - - - CR43433 - CR43433 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030722 CG12395 - http://flybase.org/reports/FBgn0030722 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12395 IPR010441:CH-like domain in sperm protein CG12395 11-Aug-17 DroID_v2017_08 "Drer\spata4, Drer\zgc:66426" - - - "Mmus\Spef1, Mmus\Spata4, Mmus\6430531B16Rik" "Hsap\SPEF1, Hsap\SPATA4" viable FBgn0043856 roo\ORF roo element ORF http://flybase.org/reports/FBgn0043856 transposable_element_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001995" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001995 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "roo\env, roo\ORF, ORF, roo, gag, pol, env" "IPR021109:Aspartic peptidase domain, IPR008737:Peptidase aspartic, putative, IPR001995:Peptidase A2A, retrovirus, catalytic, IPR005312:Protein of unknown function DUF1759, IPR022048:Envelope fusion protein-like, IPR001584:Integrase, catalytic core, IPR008042:Retrotransposon, Pao, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030247 CG15208 - http://flybase.org/reports/FBgn0030247 protein_coding_gene - sperm competition ; GO:0046692 | inferred from mutant phenotype - "anon-WO0140519.64, CG15208, lincRNA.977" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG15208 11-Aug-17 DroID_v2017_08 Drer\si:cabz01080295.1 - Cele\F09G8.5 Xtro\c21orf2 Mmus\1810043G02Rik Hsap\C21orf2 viable FBgn0039093 CG10183 - http://flybase.org/reports/FBgn0039093 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG10183 "IPR006621:Nose resistant-to-fluoxetine protein, N-terminal, IPR002656:Acyltransferase 3" CG10183 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-5, Cele\oac-31, Cele\ndg-4, Cele\oac-20, Cele\oac-50, Cele\oac-7, Cele\oac-3, Cele\nrf-6, Cele\rhy-1, Cele\oac-9, Cele\oac-55, Cele\oac-32, Cele\oac-54, Cele\oac-6, Cele\oac-46, Cele\oac-53, Cele\oac-39, Cele\oac-14" Xtro\LOC101732251 Mmus\Oacyl - viable DRSC14203 K 0.843733208 0.148688822 -0.24731013 0.352897598 -1.785955169 -1.335952468 FBgn0035243 CG13926 - http://flybase.org/reports/FBgn0035243 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13926 "IPR008493:Domain of unknown function DUF775, IPR031318:OPI10 family" CG13926 11-Aug-17 DroID_v2017_08 Drer\zgc:110091 Scer\OPI10 Cele\F42A6.6 Xtro\c11orf73 Mmus\Hikeshi Hsap\HIKESHI "viable,fertile" FBgn0041745 l(1)em4 lethal (1) em4 http://flybase.org/reports/FBgn0041745 gene - - - l(1)em4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086055 snoRNA:Me18S-C1096 - http://flybase.org/reports/FBgn0086055 snoRNA_gene - - - "snoRNA:Me18S-C1096, Me18S-Cm1096, Me18S-C1096, CR34684" - CR34684 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014160 eve::prd eve::prd http://flybase.org/reports/FBgn0014160 - engineered_fusion_gene - - - eve::prd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028838 CSN1a COP9 signalosome subunit 1a http://flybase.org/reports/FBgn0028838 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay protein deneddylation ; GO:0000338 | inferred from sequence or structural similarity with HGNC:454 COP9 signalosome ; GO:0008180 | non-traceable author statement COP9 signalosome ; GO:0008180 | inferred from biological aspect of ancestor with PANTHER:PTN000365417 COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity with MGI:MGI:2384801 inferred from sequence or structural similarity with TAIR:gene:2098850 "csn1, Dch1, CSN1, BG:DS06874.2, Dch1-1, CG4697, CH1-1, CSN1a, Csn1A, COP9, Csn1a" "IPR019585:26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1, IPR011990:Tetratricopeptide-like helical domain, IPR033008:COP9 signalosome complex subunit 1" CG4697 11-Aug-17 DroID_v2017_08 Drer\gps1 Scer\RPN7 Cele\csn-1 Xtro\gps1 Mmus\Gps1 Hsap\GPS1 viable FBgn0033317 CG8635 - http://flybase.org/reports/FBgn0033317 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8635 "IPR000571:Zinc finger, CCCH-type, IPR032378:ZC3H15/TMA46 family, C-terminal, IPR032297:Torus domain" CG8635 11-Aug-17 DroID_v2017_08 Drer\zc3h15 Scer\TMA46 "Cele\F27D4.4, Cele\Y55F3AM.6" Xtro\zc3h15 Mmus\Zc3h15 Hsap\ZC3H15 "viable,fertile" FBgn0032376 Tsp33B Tetraspanin 33B http://flybase.org/reports/FBgn0032376 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG14936, Dm.Tsp33B, Tsp33B" "IPR008952:Tetraspanin, EC2 domain" CG14936 11-Aug-17 DroID_v2017_08 "Drer\tspan15, Drer\tspan17, Drer\tspan36, Drer\tspan5b, Drer\zgc:110329, Drer\tspan5a, Drer\tspan3b" - "Cele\tsp-12, Cele\tsp-20, Cele\tsp-7" "Xtro\tspan36, Xtro\tspan3, Xtro\tspan7" "Mmus\Tspan15, Mmus\Tspan17, Mmus\Tspan5, Mmus\Tspan3, Mmus\Cd63" "Hsap\CD63, Hsap\TSPAN15, Hsap\PRPH2, Hsap\TSPAN3, Hsap\TSPAN17, Hsap\TSPAN7, Hsap\TSPAN5" "viable,fertile" DRSC02418 E -0.324509361 0.080316874 -1.630618941 -0.136923901 0.200748664 0.561493451 FBgn0266797 CR45259 - http://flybase.org/reports/FBgn0266797 non_protein_coding_gene - - - CR45259 - CR45259 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020792 palla palla http://flybase.org/reports/FBgn0020792 - gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - "palla, pla" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "follicle cell,egg,dorsal appendage" FBgn0003149 Prm Paramyosin http://flybase.org/reports/FBgn0003149 "FBgn0010949, FBgn0028212" protein_coding_gene motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR002928 motor activity ; GO:0003774 | non-traceable author statement myofibril assembly ; GO:0030239 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR002928 "prm, pm, l(3)10631, PM/mPM, FBgn0003149, CG5939, mPM, PM, Para, 0106/05, l(3)S010605, Prm" IPR002928:Myosin tail CG5939 11-Aug-17 DroID_v2017_08 "Drer\myo5ab, Drer\myhz2, Drer\myhz1.1, Drer\myo5aa, Drer\myh9a, Drer\myh11a, Drer\myo18ab, Drer\myh7bb, Drer\LOC100333572, Drer\LOC100333206, Drer\LOC100329748, Drer\vmhc, Drer\myh11b, Drer\LOC100537963, Drer\LOC100329813, Drer\smyhc1, Drer\vmhcl, Drer\myh14, Drer\myh7ba, Drer\ns:zf-e68, Drer\myo5b, Drer\myhc4, Drer\myo5c, Drer\si:dkey-110c1.10, Drer\LOC103909185, Drer\smyhc2, Drer\myh10, Drer\smyhc3, Drer\myh6, Drer\myhb, Drer\LOC100331349, Drer\myha, Drer\myo18aa, Drer\myhz1.2, Drer\myh9b" "Scer\MYO1, Scer\MYO4, Scer\MYO2" "Cele\myo-1, Cele\hum-2, Cele\hum-9, Cele\nmy-1, Cele\unc-54, Cele\myo-2, Cele\nmy-2, Cele\myo-5, Cele\myo-3, Cele\myo-6, Cele\unc-15" "Xtro\myh6, Xtro\myh8, Xtro\myh13, Xtro\myh11, Xtro\myh9, Xtro\myo5b, Xtro\myh2, Xtro\myh15, Xtro\myo18b, Xtro\myh4, Xtro\myo5a" "Mmus\Myh10, Mmus\Myh9, Mmus\Myh7, Mmus\Myh1, Mmus\Myo18b, Mmus\Myo5b, Mmus\Myh11, Mmus\Myh8, Mmus\Myh3, Mmus\Myh4, Mmus\Myo5a, Mmus\Myh15, Mmus\Myh2, Mmus\Myh6, Mmus\Myo18a, Mmus\Myh13, Mmus\Myh14, Mmus\Myo5c, Mmus\Ccdc158, Mmus\Myh7b" "Hsap\MYH15, Hsap\MYO18A, Hsap\MYH14, Hsap\MYH4, Hsap\MYH13, Hsap\MYO5B, Hsap\MYO18B, Hsap\MYH7, Hsap\MYH9, Hsap\MYH6, Hsap\MYH8, Hsap\MYO5C, Hsap\MYH7B, Hsap\MYO5A, Hsap\MYH3, Hsap\MYH10, Hsap\MYH2, Hsap\MYH1, Hsap\MYH11" "partially lethal - majority die,recessive,lethal,neurophysiology defective,flight defective,visible,some die during pupal stage" "myofibril,striated muscle myosin thick filament,sarcomere,somatic muscle,trichogen cell" FBgn0011812 Lcp1Psi Larval cuticle protein 1 pseudogene http://flybase.org/reports/FBgn0011812 FBgn0050367 pseudogene_attribute - - - "PsiLcp, LcpPsi, Lcp1Psi, Psi1, PsiI, CG30367, CR30367" - CR30367 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083114 W41 W41 http://flybase.org/reports/FBgn0083114 gene - - - W41 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable wing FBgn0266250 CR44945 - http://flybase.org/reports/FBgn0266250 non_protein_coding_gene - - - "CR44945, lincRNA.798" - CR44945 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266051 CR44816 - http://flybase.org/reports/FBgn0266051 non_protein_coding_gene - - - CR44816 - CR44816 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082588 ms(2)n55 male sterile (2) n55 http://flybase.org/reports/FBgn0082588 gene - - - "n55, ms(2)n55" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060701 l(3)S071705 lethal (3) S071705 http://flybase.org/reports/FBgn0060701 gene - - - "0717/05, l(3)S071705" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028643 bls bractless http://flybase.org/reports/FBgn0028643 gene - - - bls - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259734 Nost Nostrin http://flybase.org/reports/FBgn0259734 protein_coding_gene lipid binding ; GO:0008289 | inferred from direct assay phospholipid binding ; GO:0005543 | inferred from sequence model germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from genetic interaction with Cip4 membrane tubulation ; GO:0097320 | inferred from direct assay regulation of adherens junction organization ; GO:1903391 | inferred from genetic interaction with Cip4 plasma membrane organization ; GO:0007009 | inferred from genetic interaction with Cip4 imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with Cip4 endosome ; GO:0005768 | inferred from direct assay "CG4040, CG33224, CG15364, CG42388, NOSTRIN, Nost, nost" "IPR001060:FCH domain, IPR001452:SH3 domain, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR031160:F-BAR domain" CG42388 11-Aug-17 DroID_v2017_08 Drer\nostrin - Cele\C36E8.4 Xtro\nostrin Mmus\Nostrin Hsap\NOSTRIN FBgn0083042 snoRNA:Psi18S-1854a snoRNA:Psi18S-1854a http://flybase.org/reports/FBgn0083042 snoRNA_gene - - - "snoRNA:Psi18S-1854a, Psi18S-1854a, psi18S-1854a, Psi 18S-1854a, CR34602, chrX:16979867..16979988" - CR34602 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002600 M(2)40c Minute (2) 40c http://flybase.org/reports/FBgn0002600 - gene - - - M(2)40c - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible" macrochaeta FBgn0002892 mus206 mutagen-sensitive 206 http://flybase.org/reports/FBgn0002892 - gene - double-strand break repair ; GO:0006302 | inferred from mutant phenotype - mus206 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,radiation sensitive,DNA repair defective,sterile" FBgn0060292 snoRNA:U49:66Da snoRNA:U49:66Da http://flybase.org/reports/FBgn0060292 snoRNA_gene - - - "Dmel\U49a, U49a, CR32911, snoRNA:U49:66Da, Me28S-C3341(U49), snoRNA:U49/66Da" - CR32911 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028704 Nckx30C Nckx30C http://flybase.org/reports/FBgn0028704 protein_coding_gene "sodium ion binding ; GO:0031402 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium, potassium:sodium antiporter activity ; GO:0008273 | inferred from direct assay potassium ion binding ; GO:0030955 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium, potassium:sodium antiporter activity ; GO:0008273 | inferred from sequence or structural similarity with HGNC:10975 inferred from direct assay calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000090975" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity with HGNC:10975 inferred from direct assay neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from mutant phenotype cellular calcium ion homeostasis ; GO:0006874 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 compound eye development ; GO:0048749 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 integral component of membrane ; GO:0016021 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:10975 "CG4106, potassium-dependent sodium/calcium, CG18660, Nckx30C, NcKX30C, NckX30C" "IPR004481:Sodium/potassium/calcium exchanger, IPR004837:Sodium/calcium exchanger membrane region" CG18660 11-Aug-17 DroID_v2017_08 "Drer\slc24a2, Drer\slc24a1, Drer\slc24a5, Drer\slc24a3, Drer\slc24a4a, Drer\slc24a4b, Drer\si:ch73-335m24.5" Scer\YDL206W "Cele\ncx-4, Cele\ncx-5" "Xtro\slc24a3, Xtro\slc24a5, Xtro\slc24a2, Xtro\slc24a4" "Mmus\Slc24a5, Mmus\Slc24a2, Mmus\Slc24a3, Mmus\Slc24a4, Mmus\Slc24a1" "Hsap\SLC24A5, Hsap\SLC24A2, Hsap\SLC24A1, Hsap\SLC24A3, Hsap\SLC24A4" " embryonic stage | stage 13 , adult stage , larval stage | third instar , embryonic stage | stage 15-16 , embryonic stage | stage 16 , embryonic stage -- adult stage " " embryonic central nervous system

, eye

, dorsal mesothoracic disc | restricted

, ventral thoracic disc | restricted

, ventral nerve cord

, eye-antennal disc | restricted

, brain | restricted

, embryonic brain

, head

, dorsal metathoracic disc | restricted

" "viable,fertile" FBgn0263088 CR43356 - http://flybase.org/reports/FBgn0263088 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR43356 - CR43356 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267143 CR45583 - http://flybase.org/reports/FBgn0267143 non_protein_coding_gene - - - CR45583 - CR45583 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011290 Taf12 TBP-associated factor 12 http://flybase.org/reports/FBgn0011290 "FBgn0011303, FBgn0011304" protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf4 inferred from physical interaction with Taf1 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Taf12 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000262707 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000262707 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly ; GO:0001129 | inferred from physical interaction with Tbp RNA polymerase II activating transcription factor binding ; GO:0001102 | inferred from biological aspect of ancestor with PANTHER:PTN000262707" positive regulation of transcription of Notch receptor target ; GO:0007221 | NOT inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11545 inferred from sequence or structural similarity with SGD:S000002552 histone H3 acetylation ; GO:0043966 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11545 inferred from sequence or structural similarity with SGD:S000002552 "dTAF12, dTAF[[II]]30alpha, TAF30alpha/28/22, TAF, TFIID, TAF[[II]], dmTAF12, CG17358, TAF[II]30alpha, TAF[[II]]230, TAF12, TAF[[II]]30alpha, d28/22, TAF30alpha/28, dTAFII30 alpha, TFIID 28, TFIID 22, dTAF[[II]]30, TAFII30alpha/22, TAF[[II]]30alpha/28 TAF[[II]]22, dTAF[[II]]30alpha/22, Taf30alpha, TAF30alpha, dTAFII30, TAF30a, TAF[[II]]30alpha/28/22, dTAF28, dTAF22, Taf[[II]]30alpha, p28, p22, Taf32, Taf28, Taf22, TFIID-p28, Taf12, T2DA_DROME" "IPR003228:Transcription initiation factor TFIID, subunit 12, IPR009072:Histone-fold" CG17358 11-Aug-17 DroID_v2017_08 Drer\taf12 Scer\TAF12 "Cele\ZC53.1, Cele\taf-12" Xtro\taf12 Mmus\Taf12 Hsap\TAF12 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC28181 IK 0.158766024 2.314028454 -0.665535627 0.894596532 1.000345435 4.628406568 FBgn0260651 l(3)76BDh lethal (3) 76BDh http://flybase.org/reports/FBgn0260651 gene - - - l(3)76BDh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030911 CR15061 - http://flybase.org/reports/FBgn0030911 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15061, CR15061" - CR15061 11-Aug-17 DroID_v2017_08 - - - - - - DRSC28470 K -0.433916443 0.287138948 -0.168484679 0.041678996 -1.674889766 0.002883187 FBgn0037488 CG14607 - http://flybase.org/reports/FBgn0037488 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14607 IPR002557:Chitin binding domain CG14607 11-Aug-17 DroID_v2017_08 "Drer\cda, Drer\zgc:103586" - "Cele\cdd-2, Cele\cdd-1, Cele\Y56A3A.6, Cele\pqn-54" - "Mmus\Gm15114, Mmus\Maged1, Mmus\Tro, Mmus\Cda, Mmus\Maged2" "Hsap\MAGED2, Hsap\RAF1, Hsap\MAGED4B, Hsap\TRO, Hsap\CDA, Hsap\MAGED1, Hsap\MAGED4" viable DRSC12551 I 1.584014649 0.861477607 -0.028439761 0.503654287 0.00483301 1.021456109 FBgn0010611 Hmgs HMG Coenzyme A synthase http://flybase.org/reports/FBgn0010611 "FBgn0034115, FBgn0034116" protein_coding_gene "hydroxymethylglutaryl-CoA synthase activity ; GO:0004421 | inferred from electronic annotation with InterPro:IPR000590, InterPro:IPR010122, InterPro:IPR013528, InterPro:IPR013746" "isoprenoid biosynthetic process ; GO:0008299 | inferred from electronic annotation with InterPro:IPR000590, InterPro:IPR010122, InterPro:IPR013528, InterPro:IPR013746 lateral inhibition ; GO:0046331 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "CG4311, CG16796, l(2)06214, Hmgs, Ov25, HMGS" "IPR000590:Hydroxymethylglutaryl-coenzyme A synthase, active site, IPR010122:Hydroxymethylglutaryl-CoA synthase, eukaryotic, IPR013528:Hydroxymethylglutaryl-coenzyme A synthase, N-terminal, IPR013746:Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain, IPR016039:Thiolase-like" CG4311 11-Aug-17 DroID_v2017_08 Drer\hmgcs1 Scer\ERG13 Cele\hmgs-1 Xtro\hmgcs1 "Mmus\Hmgcs1, Mmus\Hmgcs2" "Hsap\HMGCS1, Hsap\HMGCS2" "viable,fertile,lethal,recessive,maternal effect,poor,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/first instar larval cuticle,maternal effect,abdomen,dorsal,posterior,embryonic/larval neuroblast,chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0028004 l(3)S119005 lethal (3) S119005 http://flybase.org/reports/FBgn0028004 gene - - - "1190/05, l(3)S119005" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0020812 mei(1)g13 mei(1)g13 http://flybase.org/reports/FBgn0020812 - gene - - - mei(1)g13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,female" FBgn0040957 CG14272 - http://flybase.org/reports/FBgn0040957 protein_coding_gene - - - CG14272 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267564 CR45904 - http://flybase.org/reports/FBgn0267564 non_protein_coding_gene - - - CR45904 - CR45904 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053499 Sdic4 Sperm-specific dynein intermediate chain 4 http://flybase.org/reports/FBgn0053499 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 biological_process ; GO:0008150 | no biological data available cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 sperm flagellum ; GO:0036126 | inferred from sequence or structural similarity with Sdic1 "CG33499, Sdic4, Sdic:CG33499" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2" CG33499 11-Aug-17 DroID_v2017_08 "Drer\LOC103908626, Drer\dnai2a, Drer\dync1i2b, Drer\dnai1.1, Drer\dync1i1" "Scer\PAC11, Scer\PFS2" "Cele\dyci-1, Cele\prp-17, Cele\C27F2.1" "Xtro\dync1i1, Xtro\dync1i2" "Mmus\Dync1i2, Mmus\Wdr63, Mmus\Dync1i1" "Hsap\DYNC1I1, Hsap\DYNC1I2, Hsap\WDR60" FBgn0011862 tRNA:Gly-GCC-1-4 transfer RNA:Glycine-GCC 1-4 http://flybase.org/reports/FBgn0011862 "FBgn0003778, FBgn0051977, FBgn0060223" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "BG:DS04641.3, AE002690.trna10-GlyGCC, tRNA:G:GCC:AE002690-b, CR31977, tRNA:gly3:35Ba, tRNA[Gly-GCC], chr2L.trna19-GlyGCC, tRNA-Gly-GCC-1-4, tRNA:Gly-GCC-1-4, tRNA:G3:35Ba, GGC" - CR31977 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266825 CR45287 - http://flybase.org/reports/FBgn0266825 non_protein_coding_gene - - - CR45287 - CR45287 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038246 CG14853 - http://flybase.org/reports/FBgn0038246 protein_coding_gene - - - CG14853 "IPR026703:Glutamate-rich protein 2, IPR011990:Tetratricopeptide-like helical domain" CG14853 11-Aug-17 DroID_v2017_08 Drer\erich2 - - - Mmus\Erich2 Hsap\ERICH2 viable FBgn0263046 CG43341 - http://flybase.org/reports/FBgn0263046 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43341, CG30492" - CG43341 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001785 l(1)M83 lethal (1) M83 http://flybase.org/reports/FBgn0001785 - gene - - - l(1)M83 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0016710 Reg-15 Rhythmically expressed gene 15 http://flybase.org/reports/FBgn0016710 - gene - - - "Dreg-15, Reg-15" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , embryonic stage | late " adult head

FBgn0265044 CR44161 - http://flybase.org/reports/FBgn0265044 non_protein_coding_gene - - - CR44161 - CR44161 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001147 gsb-n gooseberry-neuro http://flybase.org/reports/FBgn0001147 - protein_coding_gene RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay DNA binding ; GO:0003677 | non-traceable author statement "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001523, InterPro:IPR017970 segment polarity determination ; GO:0007367 | inferred from genetic interaction with gsb neurogenesis ; GO:0022008 | inferred from genetic interaction with gsb segment polarity determination ; GO:0007367 | inferred from expression pattern" nucleus ; GO:0005634 | inferred from direct assay "GsbN, gsbn, gsb, gsb-p, gsbp, BSH4, gsb-neuro, Gsb-p, BSH-4, CG2692, gsb-n, Gsbn, gsbN, Gsb-n" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG2692 11-Aug-17 DroID_v2017_08 "Drer\pax6a, Drer\mixl1, Drer\pax7b, Drer\mxtx2, Drer\pax6b, Drer\pax3a, Drer\pax4, Drer\pax7a, Drer\msx3, Drer\pax2a, Drer\arxa, Drer\pax8, Drer\pax1b, Drer\pax1a, Drer\arxb, Drer\pax9, Drer\pax10, Drer\pax5, Drer\pax2b, Drer\pax3b, Drer\mxtx1" - "Cele\alr-1, Cele\mls-2, Cele\pax-2, Cele\pax-1, Cele\pax-3, Cele\vab-3, Cele\egl-38" "Xtro\pax9, Xtro\pax8, Xtro\mixer, Xtro\bix1.1, Xtro\pax2, Xtro\mix1, Xtro\pax1, Xtro\arx, Xtro\pax3, Xtro\pax7, Xtro\sia1, Xtro\pax5, Xtro\pax6" "Mmus\Pax5, Mmus\Arx, Mmus\Pax1, Mmus\Pax3, Mmus\Cphx3, Mmus\Pax4, Mmus\Pax2, Mmus\Mixl1, Mmus\Pax8, Mmus\Cphx1, Mmus\Duxbl3, Mmus\Pax7, Mmus\Pax9, Mmus\Duxbl1, Mmus\Duxbl2, Mmus\Pax6" "Hsap\PAX4, Hsap\PAX8, Hsap\PAX7, Hsap\PAX5, Hsap\PAX1, Hsap\DUX4, Hsap\PAX3, Hsap\PAX2, Hsap\PAX9, Hsap\MIXL1, Hsap\ARX, Hsap\PAX6, Hsap\DUXA" " embryonic stage | stage 12 , embryonic stage | stage 13 , embryonic stage | late , embryonic stage | >=stage 9 , embryonic stage | stage 11 , larval stage , embryonic stage | 4-12 hr , embryonic stage | stage 9 , embryonic stage " " embryonic neuroblast

, embryonic neuron | segmentally repeated pattern

, organism | striped

, ventral neurogenic region | segmentally repeated

, epidermis

, neuroblast

, ventral nervous system

" " embryonic stage | stage >13 , embryonic stage | stage >11 , embryonic stage | stage 10 , embryonic stage | stage >10 , larval stage | third instar " " neuron &&of abdominal segment 9

, embryonic neuron | segmentally repeated pattern

, ganglion mother cell

, anal pad

, embryonic/larval pharynx

, embryonic neuron

, ventral oblique muscle

, female genital disc | restricted

, neuron &&of embryonic brain

, male genital disc | restricted

, neuroblast

" "partially lethal - majority live,partially lethal - majority die,recessive,pair rule phenotype,wild-type" "RP2 motor neuron,EL neuron,U neuron,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,embryonic epidermis,Keilin's organ,aCC neuron,pCC neuron" FBgn0011101 l(1)Q62 lethal (1) Q62 http://flybase.org/reports/FBgn0011101 FBgn0010210 gene - - - l(1)Q62 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037878 CG6693 - http://flybase.org/reports/FBgn0037878 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6693 "IPR001623:DnaJ domain, IPR018253:DnaJ domain, conserved site" CG6693 11-Aug-17 DroID_v2017_08 Drer\dnajc9 - Cele\dnj-23 Xtro\dnajc9 Mmus\Dnajc9 Hsap\DNAJC9 FBgn0025104 CalpII Calpain II http://flybase.org/reports/FBgn0025104 - gene calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay - CalpII - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050334 CG30334 - http://flybase.org/reports/FBgn0050334 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs09a11, CG30334" - CG30334 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010847 l(3)04708 lethal (3) 04708 http://flybase.org/reports/FBgn0010847 - gene - - - l(3)04708 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0259580 B2026 - http://flybase.org/reports/FBgn0259580 gene - - - B2026 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0267423 CR45776 - http://flybase.org/reports/FBgn0267423 pseudogene_attribute - - - "CR45776, Mst77Y" - CR45776 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036439 CG13474 - http://flybase.org/reports/FBgn0036439 protein_coding_gene adenosine kinase activity ; GO:0004001 | inferred from electronic annotation with InterPro:IPR001805 molecular_function ; GO:0003674 | no biological data available purine ribonucleoside salvage ; GO:0006166 | inferred from electronic annotation with InterPro:IPR001805 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT29351, CG13474" "IPR001805:Adenosine kinase, IPR029056:Ribokinase-like, IPR011611:Carbohydrate kinase PfkB" CG13474 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC10018 IE 0.010564706 -1.832633119 0.054269873 -1.839346939 -0.987484971 0.423756823 FBgn0011191 l(1)296-19 lethal (1) 296-19 http://flybase.org/reports/FBgn0011191 FBgn0010201 gene - - - "296-19, l(1)296-19" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035478 CG10853 - http://flybase.org/reports/FBgn0035478 protein_coding_gene - - - "BcDNA:LP09837, CG10853" - CG10853 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" DRSC23600 IK -0.322274411 1.896518952 0.242037808 0.629290473 -1.511820929 0.244926703 FBgn0024853 moz mozzarella http://flybase.org/reports/FBgn0024853 - gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "ms(2)UK, ms(2)5720, moz2, moz1, moz" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,viable" "spermatozoon,primary spermatocyte cyst,spermatid & nucleus" FBgn0000548 E(da) Enhancer of daughterless http://flybase.org/reports/FBgn0000548 - gene - - - E(da) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031155 CG15446 - http://flybase.org/reports/FBgn0031155 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG15446 IPR013087:Zinc finger C2H2-type CG15446 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038274 Nup93-2 Nucleoporin 93kD-2 http://flybase.org/reports/FBgn0038274 protein_coding_gene structural constituent of nuclear pore ; GO:0017056 | inferred from sequence or structural similarity with SGD:S000001898 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR007231 nuclear pore organization ; GO:0006999 | inferred from sequence or structural similarity with SGD:S000001898 nuclear pore nuclear basket ; GO:0044615 | inferred from sequence or structural similarity with SGD:S000001898 "CG7262, Cg7262, nup93, Nup93-2, Nup93" "IPR007231:Nucleoporin interacting component Nup93/Nic96, IPR011990:Tetratricopeptide-like helical domain" CG7262 11-Aug-17 DroID_v2017_08 Drer\nup93 Scer\NIC96 Cele\npp-13 Xtro\nup93 Mmus\Nup93 Hsap\NUP93 viable FBgn0030617 CG9095 - http://flybase.org/reports/FBgn0030617 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - "CT26106, CG9095" "IPR000436:Sushi/SCR/CCP domain, IPR001304:C-type lectin-like, IPR008979:Galactose-binding domain-like, IPR018378:C-type lectin, conserved site, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold, IPR015943:WD40/YVTN repeat-like-containing domain, IPR006585:Fucolectin tachylectin-4 pentraxin-1" CG9095 11-Aug-17 DroID_v2017_08 "Drer\cfhl2, Drer\cfhl3, Drer\zgc:152863, Drer\sez6a, Drer\cfh, Drer\cfhl1, Drer\susd6, Drer\selp" - "Cele\C54G4.4, Cele\lev-9" "Xtro\brf1, Xtro\selp" "Mmus\Selp, Mmus\Sell, Mmus\Susd6, Mmus\Sez6, Mmus\Sele" "Hsap\SEZ6, Hsap\SELE, Hsap\SELP, Hsap\SELL, Hsap\SUSD6" "viable,fertile" FBgn0260221 5-SZ-3716 - http://flybase.org/reports/FBgn0260221 gene - - - 5-SZ-3716 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "sex comb,sex comb tooth" FBgn0034401 MetRS Methionyl-tRNA synthetase http://flybase.org/reports/FBgn0034401 protein_coding_gene "methionine-tRNA ligase activity ; GO:0004825 | inferred from electronic annotation with InterPro:IPR014758, InterPro:IPR023458 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000738, InterPro:IPR001412, InterPro:IPR009080, InterPro:IPR014758, InterPro:IPR015413 methionine-tRNA ligase activity ; GO:0004825 | inferred from sequence or structural similarity methionine-tRNA ligase activity ; GO:0004825 | traceable author statement" methionyl-tRNA aminoacylation ; GO:0006431 | inferred from electronic annotation with InterPro:IPR014758 methionyl-tRNA aminoacylation ; GO:0006431 | traceable author statement methionyl-tRNA aminoacylation ; GO:0006431 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000235771 microtubule associated complex ; GO:0005875 | inferred from direct assay "MRS, p120, clone 2.15, anon-EST:Liang-2.15, CG15100, MetRS, dMetRS" "IPR000738:WHEP-TRS domain, IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR009068:S15/NS1, RNA-binding, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR010987:Glutathione S-transferase, C-terminal-like, IPR023458:Methionine-tRNA ligase, type 1, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR014758:Methionyl-tRNA synthetase, IPR015413:Methionyl/Leucyl tRNA synthetase, IPR033911:Methioninyl-tRNA synthetase core domain, IPR004045:Glutathione S-transferase, N-terminal, IPR029038:Methionyl-tRNA synthetase, Zn-domain, IPR004046:Glutathione S-transferase, C-terminal" CG15100 11-Aug-17 DroID_v2017_08 Drer\mars Scer\MES1 Cele\mars-1 Xtro\mars Mmus\Mars Hsap\MARS "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0034665 CG4372 - http://flybase.org/reports/FBgn0034665 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000246 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4372 "IPR000246:Peptidase T2, asparaginase 2, IPR029055:Nucleophile aminohydrolases, N-terminal" CG4372 11-Aug-17 DroID_v2017_08 "Drer\aga, Drer\zgc:153169" - Cele\R04B3.2 Xtro\aga Mmus\Aga Hsap\AGA viable FBgn0027130 l(3)C109 lethal (3) C109 http://flybase.org/reports/FBgn0027130 - gene - - - l(3)C109 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262879 CR43234 - http://flybase.org/reports/FBgn0262879 non_protein_coding_gene - - - "CG43234, CR43234" - CR43234 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027158 l(2)PN-6 lethal (2) PN-6 http://flybase.org/reports/FBgn0027158 - gene - - - l(2)PN-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265398 EP1618 - http://flybase.org/reports/FBgn0265398 gene - - - EP1618 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0243511 psidin phagocyte signaling impaired http://flybase.org/reports/FBgn0243511 protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000511059 actin filament binding ; GO:0051015 | inferred from direct assay "border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype inferred from genetic interaction with tsr immune response ; GO:0006955 | inferred from mutant phenotype N-terminal peptidyl-methionine acetylation ; GO:0017196 | inferred from biological aspect of ancestor with PANTHER:PTN000511059 sensory neuron axon guidance ; GO:0097374 | inferred from mutant phenotype positive regulation of lamellipodium assembly ; GO:0010592 | inferred from mutant phenotype actin filament depolymerization ; GO:0030042 | inferred from genetic interaction with tsr activation of immune response ; GO:0002253 | inferred from mutant phenotype phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype" lysosome ; GO:0005764 | inferred from direct assay NatB complex ; GO:0031416 | inferred from physical interaction with Naa20A neuron projection ; GO:0043005 | inferred from direct assay growth cone lamellipodium ; GO:1990761 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG4845, psidin, ird16, psid, Naa25" "IPR013026:Tetratricopeptide repeat-containing domain, IPR011990:Tetratricopeptide-like helical domain, IPR019183:N-acetyltransferase B complex, non-catalytic subunit" CG4845 11-Aug-17 DroID_v2017_08 Drer\naa25 Scer\MDM20 Cele\cra-1 Xtro\naa25 Mmus\Naa25 Hsap\NAA25 FBgn0016840 l(1)MZ9 lethal (1) MZ9 http://flybase.org/reports/FBgn0016840 - gene - - - "l(1)MZ9, M9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261878 Z2-2729 - http://flybase.org/reports/FBgn0261878 gene - sleep ; GO:0030431 | inferred from mutant phenotype - Z2-2729 - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective FBgn0051025 Ppi1 Protein phosphatase 1c interacting protein 1 http://flybase.org/reports/FBgn0051025 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B - - "CG2164, anon-WO0140519.94, CG31025, Ppi1, ppi1" "IPR031949:Domain of unknown function DUF4776, IPR031992:Domain of unknown function DUF4788" CG31025 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC15421 E -0.336677409 -0.582472439 -1.762603895 -0.686971283 -0.348750529 1.307820621 FBgn0264280 Su(Mir)3D1-1 - http://flybase.org/reports/FBgn0264280 gene - - - Su(Mir)3D1-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052069 CG32069 - http://flybase.org/reports/FBgn0052069 protein_coding_gene - ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000407112 neurogenesis ; GO:0022008 | inferred from mutant phenotype ER to Golgi transport vesicle ; GO:0030134 | inferred from biological aspect of ancestor with PANTHER:PTN000407112 endomembrane system ; GO:0012505 | inferred from direct assay integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000407112 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000407112 "CG6316, CG32069" IPR013880:Yos1-like CG32069 11-Aug-17 DroID_v2017_08 "Drer\hdhd2, Drer\ier3ip1, Drer\lhpp" Scer\YOS1 "Cele\W09G3.8, Cele\C13C4.4, Cele\K08B12.3" Xtro\ier3ip1 "Mmus\Lhpp, Mmus\Ier3ip1, Mmus\Hdhd2" "Hsap\IER3IP1, Hsap\HDHD2, Hsap\LHPP" "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0052219 CG32219 - http://flybase.org/reports/FBgn0052219 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "BcDNA:AT25132, CG32219" - CG32219 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0054006 CR34006 - http://flybase.org/reports/FBgn0054006 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1010, CG34006, CR34006" - CR34006 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005170 l(2)G571 lethal (2) G571 http://flybase.org/reports/FBgn0005170 - gene - - - l(2)G571 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060387 l(3)S134304b lethal (3) S134304b http://flybase.org/reports/FBgn0060387 gene - - - "1343/04, l(3)S134304b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0051889 tRNA:Asp-GTC-1-7 transfer RNA:Aspartic acid-GTC 1-7 http://flybase.org/reports/FBgn0051889 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "AE002690.trna7-AspGTC, tRNA:asp2:29E, tRNA:D2:29E, tRNA:D:GTC:AE002690-c, CR31889, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna16-AspGTC, tRNA:Asp-GTC-1-7, tRNA:CR31889, tRNA-Asp-GTC-1-7, GAC" - CR31889 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044387 Scim7 Sensitized chromosome inheritance modifier 7 http://flybase.org/reports/FBgn0044387 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0047205 CR32385 - http://flybase.org/reports/FBgn0047205 non_protein_coding_gene - - - "LD18889, BcDNA:LD18889, anon-WO0118547.23, CR32385" - CR32385 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060739 l(3)S066620b lethal (3) S066620b http://flybase.org/reports/FBgn0060739 gene - - - "0666/20, l(3)S066620b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003440 smh smaller thinner http://flybase.org/reports/FBgn0003440 - gene - - - smh - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" macrochaeta FBgn0267252 Ggamma30A G protein subunit gamma at 30A http://flybase.org/reports/FBgn0267252 protein_coding_gene "signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR001770, InterPro:IPR015898 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Gβ76C" regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from physical interaction with Gβ76C G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay cellular response to carbon dioxide ; GO:0071244 | inferred from mutant phenotype heterotrimeric G-protein complex ; GO:0005834 | inferred from physical interaction with Gβ76C cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay "Ggamma30A, GNG gene like, lincRNA.S701, Ggamma, Ggammae, G[[gamma]], Ggamma[[e]], CG18511, CG3694, Galpha30A, G-gamma30A, G[[gamma30A]], CG43733" "IPR001770:G-protein, gamma subunit, IPR015898:G-protein gamma-like domain" CG3694 11-Aug-17 DroID_v2017_08 "Drer\gngt1, Drer\si:dkey-204f11.64, Drer\gng2, Drer\gng10, Drer\gngt2b, Drer\gng8, Drer\si:dkey-44g17.6, Drer\si:dkey-117i10.1, Drer\gngt2a, Drer\gng5, Drer\gng13b, Drer\gng13a, Drer\gng7, Drer\gng3, Drer\gng12a" - "Cele\gpc-2, Cele\gpc-1" "Xtro\gngt1, Xtro\gng2, Xtro\gng7, Xtro\gng5, Xtro\gng13" "Mmus\Gng2, Mmus\Gng10, Mmus\Gng3, Mmus\Gngt2, Mmus\Gng12, Mmus\Gng13, Mmus\Gm5741, Mmus\Gngt1, Mmus\Gng8, Mmus\Gng7, Mmus\Gng4, Mmus\Gng5, Mmus\Gng11" "Hsap\GNG8, Hsap\GNG12, Hsap\GNG4, Hsap\GNGT1, Hsap\GNG5, Hsap\GNG7, Hsap\GNG2, Hsap\GNG13, Hsap\GNG11, Hsap\GNG10, Hsap\GNGT2, Hsap\GNG3" adult stage head

adult stage " medulla

, photoreceptor cell

, lamina

" FBgn0024326 Mkk4 MAP kinase kinase 4 http://flybase.org/reports/FBgn0024326 "FBgn0024950, FBgn0040310" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 MAP kinase kinase activity ; GO:0004708 | traceable author statement receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement" protein phosphorylation ; GO:0006468 | non-traceable author statement JNK cascade ; GO:0007254 | inferred from genetic interaction with hep inferred from genetic interaction with egr neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from genetic interaction with Ask1 neuron development ; GO:0048666 | inferred from mutant phenotype activation of JUN kinase activity ; GO:0007257 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 axon ; GO:0030424 | inferred from direct assay "SEK1/MKK4, 142758_at, dMKK4, mkk4, MKK4, CT27508, CG9738, JNKK2, D-MKK4, DMKK4, Mpk4, Mkk4, P-MKK4, hep, MAPKK4, dMkk4" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG9738 11-Aug-17 DroID_v2017_08 "Drer\map2k4a, Drer\map2k4b, Drer\map2k7, Drer\map2k2a, Drer\map2k6" "Scer\STE7, Scer\PBS2" "Cele\jkk-1, Cele\sek-3, Cele\mek-1, Cele\sek-6, Cele\sek-1, Cele\mek-2, Cele\sek-5, Cele\sek-4, Cele\mkk-4" "Xtro\map2k4, Xtro\map2k6, Xtro\map2k1, Xtro\map2k7" "Mmus\Map2k7, Mmus\Map2k3, Mmus\Map2k4, Mmus\Map2k2, Mmus\Map2k1, Mmus\Map2k6" "Hsap\MAP2K4, Hsap\MAP2K1, Hsap\MAP2K3, Hsap\MAP2K6, Hsap\MAP2K7, Hsap\MAP2K2" embryonic stage "

ubiquitous , ventral nerve cord

" "neuroanatomy defective,somatic clone,viable,visible" "Kenyon cell,somatic clone,axon | somatic clone,trichogen cell" FBgn0267431 Myo81F Myosin 81F http://flybase.org/reports/FBgn0267431 protein_coding_gene "motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000159 biological_process ; GO:0008150 | no biological data available myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609 myosin complex ; GO:0016459 | inferred from sequence or structural similarity "CG15831, CG42621, CG40155, CG42622, CG41518, CG42623, CG40204, CG42624, CG41281, CG41527, Myo81F, CG45784" "IPR019748:FERM central domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000857:MyTH4 domain, IPR000048:IQ motif, EF-hand binding site, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain, IPR011993:PH domain-like, IPR001609:Myosin head, motor domain, IPR000159:Ras-associating (RA) domain, IPR000299:FERM domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle" CG45784 11-Aug-17 DroID_v2017_08 - Scer\MYO2 - - - - FBgn0067668 p160M p160M http://flybase.org/reports/FBgn0067668 gene - - - "p160, p160M" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040550 CG14389 - http://flybase.org/reports/FBgn0040550 protein_coding_gene - - - CG14389 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000978 fs(2)HO164 female sterile (2) HO164 http://flybase.org/reports/FBgn0000978 - gene - - - "fs(2)164A, fs(2)HO164" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260503 Pkc53E::Pkn - http://flybase.org/reports/FBgn0260503 engineered_fusion_gene - - - "Pkc53E::Pkn, Pkn-PKC53E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0037040 CG12983 - http://flybase.org/reports/FBgn0037040 protein_coding_gene - - - "bs29a07.y1, NEST:bs29a07, CG12983" "IPR022110:Casc1 domain, IPR031826:Cancer susceptibility candidate 1, N-terminal" CG12983 11-Aug-17 DroID_v2017_08 Drer\casc1 - Cele\K09E2.2 - Mmus\Casc1 Hsap\CASC1 viable FBgn0283471 wupA wings up A http://flybase.org/reports/FBgn0283471 protein_coding_gene actin binding ; GO:0003779 | non-traceable author statement skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype muscle contraction ; GO:0006936 | inferred from biological aspect of ancestor with PANTHER:PTN000348305 muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype nuclear division ; GO:0000280 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype cardiac muscle tissue development ; GO:0048738 | inferred from mutant phenotype heart contraction ; GO:0060047 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype troponin complex ; GO:0005861 | inferred from biological aspect of ancestor with PANTHER:PTN000348305 troponin complex ; GO:0005861 | non-traceable author statement nucleus ; GO:0005634 | colocalizes_with inferred from direct assay "wupA, fliH, TnI, hdp-a, hdp, CG7178, TpnI, HL08042, wup-A, HL-I, DROTROPONI, HLI, HDP, Tn I, DmTpnI, WupA, hdp2, chrX:17947374..17947524" IPR001978:Troponin CG7178 11-Aug-17 DroID_v2017_08 "Drer\tnni2b.1, Drer\tnni1al, Drer\zgc:101560, Drer\tnni2a.4, Drer\tnni2a.2, Drer\tnni2b.2, Drer\tnni1a, Drer\zgc:112242, Drer\tnni1c, Drer\tnni2a.3, Drer\tnni2a.1, Drer\si:dkey-206m15.8, Drer\tnni1d, Drer\tnni1b" - "Cele\tni-3, Cele\tni-1, Cele\unc-27, Cele\tni-4" "Xtro\tnni2, Xtro\tnni1, Xtro\tnni1, Xtro\tnni3" "Mmus\Tnni2, Mmus\Tnni1, Mmus\Tnni3" "Hsap\TNNI3, Hsap\TNNI2, Hsap\TNNI1" FBgn0070051 37 37 http://flybase.org/reports/FBgn0070051 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "#37, 37" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052392 CG32392 - http://flybase.org/reports/FBgn0052392 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "CG10099, CG14912, CG32392" IPR009290:Radial spoke 3 CG32392 11-Aug-17 DroID_v2017_08 Drer\rsph3 - - Xtro\rsph3 "Mmus\Rsph3a, Mmus\Rsph3b" Hsap\RSPH3 viable DRSC10211 K 0.749526917 0.218008449 0.249511587 0.641071253 0.5324798 -1.727269421 FBgn0062614 Mod(var)1260 Mod(var)1260 http://flybase.org/reports/FBgn0062614 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1260, Mod(var)1260" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0026684 l(1)G0078 lethal (1) G0078 http://flybase.org/reports/FBgn0026684 - gene - - - l(1)G0078 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025178 l(1)1070 lethal (1) 1070 http://flybase.org/reports/FBgn0025178 - gene - - - l(1)1070 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "egg chamber,maternal effect,somatic clone,chorion | maternal effect | somatic clone,follicle cell" FBgn0015458 l(2)37CDc lethal (2) 37CDc http://flybase.org/reports/FBgn0015458 FBgn0013293 gene - - - "l(2)E151, l(2)37CDc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" macrochaeta FBgn0267200 CR45640 - http://flybase.org/reports/FBgn0267200 non_protein_coding_gene - - - CR45640 - CR45640 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020833 l(2)NA "North Amherst, Mass" http://flybase.org/reports/FBgn0020833 - gene - - - l(2)NA - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051551 CG31551 - http://flybase.org/reports/FBgn0051551 protein_coding_gene - - - "CG11005, CG31551" - CG31551 11-Aug-17 DroID_v2017_08 Drer\si:ch211-116m6.3 - "Cele\F49E2.5, Cele\che-10, Cele\H39E23.3, Cele\ajm-1" - "Mmus\Tchh, Mmus\Nefh" "Hsap\TCHH, Hsap\NEFH" lethal DRSC22403 I 1.234520337 -1.892002965 1.212805483 0.329119309 0.651052808 0.19906572 FBgn0014976 l(1)64 lethal (1) 64 http://flybase.org/reports/FBgn0014976 - gene - - - l(1)64 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032753 CG17572 - http://flybase.org/reports/FBgn0032753 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "c-SPH64, SPH64, CG17572" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG17572 11-Aug-17 DroID_v2017_08 "Drer\f10, Drer\f9a" - "Cele\try-1, Cele\svh-1" - "Mmus\Prss51, Mmus\Klk1b9, Mmus\Klk1b5, Mmus\Prss8" Hsap\PRSS8 "partially lethal - majority die,some die during pupal stage" FBgn0052368 CG32368 - http://flybase.org/reports/FBgn0052368 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RH61042, CG32368" - CG32368 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0050465 CG30465 - http://flybase.org/reports/FBgn0050465 protein_coding_gene - - - "BcDNA:RH63320, CG30465" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067884 Mod(Prat:bw)1-3 Mod(Prat:bw)1-3 http://flybase.org/reports/FBgn0067884 gene - - - "Mod-1-3, Mod(Prat:bw)1-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067666 p58 p58 http://flybase.org/reports/FBgn0067666 gene - - - p58 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036670 CG13029 - http://flybase.org/reports/FBgn0036670 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "BcDNA:AT31918, anon-WO0118547.38, CG13029" "IPR001594:Palmitoyltransferase, DHHC domain" CG13029 11-Aug-17 DroID_v2017_08 "Drer\zdhhc20a, Drer\zdhhc18a, Drer\zdhhc5b, Drer\zdhhc9, Drer\zgc:77880, Drer\zdhhc12b, Drer\zdhhc23a, Drer\zdhhc24, Drer\zdhhc5a, Drer\zdhhc14, Drer\zdhhc23b, Drer\zdhhc21, Drer\LOC100334198, Drer\zdhhc22, Drer\zdhhc8b, Drer\zdhhc12a, Drer\zdhhc1, Drer\zdhhc3b, Drer\zdhhc7, Drer\zdhhc20b, Drer\zdhhc3a" "Scer\ERF2, Scer\PFA5" "Cele\dhhc-10, Cele\dhhc-9, Cele\dhhc-12, Cele\dhhc-1" "Xtro\dnz1, Xtro\zdhhc7, Xtro\zdhhc21, Xtro\zdhhc24, Xtro\zdhhc1, Xtro\zdhhc9, Xtro\zdhhc3, Xtro\zdhhc12, Xtro\zdhhc14, Xtro\zdhhc8" "Mmus\Zdhhc12, Mmus\Zdhhc20, Mmus\Zdhhc19, Mmus\Zdhhc8, Mmus\Zdhhc25, Mmus\Zdhhc21, Mmus\Zdhhc7, Mmus\Zdhhc14, Mmus\Zdhhc5, Mmus\Zdhhc9, Mmus\Zdhhc1, Mmus\Zdhhc24, Mmus\Zdhhc4, Mmus\Zdhhc11, Mmus\Zdhhc3, Mmus\Zdhhc22, Mmus\Zdhhc18, Mmus\Zdhhc23" "Hsap\ZDHHC18, Hsap\ZDHHC4, Hsap\ZDHHC1, Hsap\ZDHHC21, Hsap\ZDHHC7, Hsap\ZDHHC22, Hsap\ZDHHC20, Hsap\ZDHHC24, Hsap\ZDHHC14, Hsap\ZDHHC12, Hsap\ZDHHC23, Hsap\ZDHHC11, Hsap\ZDHHC3, Hsap\ZDHHC5, Hsap\ZDHHC8, Hsap\ZDHHC9, Hsap\ZDHHC19" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266492 SclB Sarcolamban B http://flybase.org/reports/FBgn0266492 protein_coding_gene - regulation of cardiac muscle contraction ; GO:0055117 | inferred from mutant phenotype - "ORF-B, pncr:003:2L, SclB, pncr003:2L, mel2, BcDNA:RE28911, BEST:LP06756, CR31696, scl, pncr003:2L ORFB, CG45091, pncr003" - CG45091 11-Aug-17 DroID_v2017_08 - - - - - - adult heart FBgn0067355 l(3)95EFa lethal (3) 95EFa http://flybase.org/reports/FBgn0067355 gene - - - l(3)95EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013941 E(sina)6 Enhancer of seven in absentia 6 http://flybase.org/reports/FBgn0013941 - gene - - - E(sina)6 - - 11-Aug-17 DroID_v2017_08 - - - - - - photoreceptor cell R7 FBgn0265492 BG01602 - http://flybase.org/reports/FBgn0265492 gene - - - BG01602 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069182 mcl(2)Z0338 mcl(2)Z0338 http://flybase.org/reports/FBgn0069182 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z0338 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0038585 Non3 Novel nucleolar protein 3 http://flybase.org/reports/FBgn0038585 protein_coding_gene rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000296192 "mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000463 | inferred from biological aspect of ancestor with PANTHER:PTN000296192 neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000296192" nucleolus ; GO:0005730 | inferred from direct assay "Non3, CG7993" IPR007109:Brix domain CG7993 11-Aug-17 DroID_v2017_08 Drer\rpf2 Scer\RPF2 Cele\Y54E10A.10 Xtro\rpf2 Mmus\Rpf2 Hsap\RPF2 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0250731 5.8SrRNA:CR40454 5.8SrRNA:CR40454 http://flybase.org/reports/FBgn0250731 rRNA_gene - - - "5.8SrRNA:CR40454, CR40454" - CR40454 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029962 CG1402 - http://flybase.org/reports/FBgn0029962 protein_coding_gene - - - CG1402 "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class" CG1402 11-Aug-17 DroID_v2017_08 "Drer\ca4b, Drer\ca4c, Drer\ca9, Drer\ca12, Drer\ca2, Drer\ca6, Drer\zgc:153760, Drer\ca14, Drer\ca15b, Drer\cahz, Drer\ca7, Drer\ca15a, Drer\ca10b, Drer\car15, Drer\ca10a, Drer\ca16b, Drer\ca4a, Drer\ca15c, Drer\ca8, Drer\ca5a, Drer\ptprga" - "Cele\cah-2, Cele\cah-1" "Xtro\ca6, Xtro\ca3, Xtro\ca5b, Xtro\ca1, Xtro\ca14, Xtro\ca10, Xtro\ca12, Xtro\ca7, Xtro\ca11, Xtro\ca4, Xtro\LOC779564, Xtro\ca8, Xtro\ca2" "Mmus\Car1, Mmus\Car12, Mmus\Ptprg, Mmus\Car4, Mmus\Car8, Mmus\Car7, Mmus\Car5a, Mmus\Car10, Mmus\Car13, Mmus\Car11, Mmus\Car5b, Mmus\Car3, Mmus\Car14, Mmus\Car15, Mmus\Car2, Mmus\Car9, Mmus\Car6" "Hsap\CA5A, Hsap\CA4, Hsap\CA2, Hsap\CA5B, Hsap\CA9, Hsap\CA12, Hsap\CA8, Hsap\CA7, Hsap\CA3, Hsap\CA11, Hsap\PTPRG, Hsap\CA13, Hsap\CA6, Hsap\CA1, Hsap\CA14, Hsap\CA10" viable DRSC17905 I -0.312340393 1.769573916 -0.106505895 0.307861083 -0.252666746 -0.153191377 FBgn0028430 He Hemese http://flybase.org/reports/FBgn0028430 protein_coding_gene - innate immune response ; GO:0045087 | inferred from mutant phenotype encapsulation of foreign target ; GO:0035010 | traceable author statement negative regulation of lamellocyte differentiation ; GO:0035204 | traceable author statement - "H2, CG31770, He, he, hem" - CG31770 11-Aug-17 DroID_v2017_08 - - - - - - "immune response defective,viable" "lamellocyte,ectopic,hemocyte" FBgn0259866 Su(Ste):CR42435 Su(Ste):CR42435 http://flybase.org/reports/FBgn0259866 non_protein_coding_gene - - - "Su(Ste):CR42435, CR42435" - CR42435 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001844 l(1)ts1891 lethal (1) ts1891 http://flybase.org/reports/FBgn0001844 - gene - - - l(1)ts1891 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0035216 CG9168 - http://flybase.org/reports/FBgn0035216 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular space ; GO:0005615 | inferred from direct assay "CG9168, gi23092768" "IPR004245:Protein of unknown function DUF229, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG9168 11-Aug-17 DroID_v2017_08 - - "Cele\Y41E3.1, Cele\T07G12.3, Cele\T23E1.1, Cele\F07C3.3, Cele\R03G8.1, Cele\M03F8.5, Cele\F32G8.2, Cele\R03G8.3, Cele\Y38A10A.2, Cele\K03A11.4, Cele\F10C2.3, Cele\Y73F8A.35, Cele\F15H10.7, Cele\F32D8.2" - - - viable FBgn0267171 CR45611 - http://flybase.org/reports/FBgn0267171 non_protein_coding_gene - - - CR45611 - CR45611 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019907 anon-14Bc anon-14Bc http://flybase.org/reports/FBgn0019907 - gene - - - anon-14Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262852 CR43216 - http://flybase.org/reports/FBgn0262852 pseudogene_attribute - - - "CR43216, noncoding_23159, noncoding_23161" - CR43216 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052752 CG32752 - http://flybase.org/reports/FBgn0052752 protein_coding_gene - - - CG32752 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262203 mir-967 mir-967 stem loop http://flybase.org/reports/FBgn0262203 miRNA_gene - - - "miR-967, mir-967, CR42910, dme-mir-967" - CR42910 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002293 l(3)80Fd lethal (3) 80Fd http://flybase.org/reports/FBgn0002293 - gene - - - "l5B, l(3)Lh5, l(3)80Fd, 80Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029032 l(2)R209 lethal (2) R209 http://flybase.org/reports/FBgn0029032 gene - - - "R209, l(2)R209" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067052 Rab9D Rab at 9D http://flybase.org/reports/FBgn0067052 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 plasma membrane ; GO:0005886 | inferred from direct assay endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 "anon-AE003451.1, CG32678, Rab9D" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG32678 11-Aug-17 DroID_v2017_08 "Drer\rab1aa, Drer\rab1ab, Drer\rab1ba, Drer\rab35b, Drer\rabl6b, Drer\si:dkey-16l2.16, Drer\rab35a, Drer\zgc:101559, Drer\rab33a, Drer\rab19, Drer\rabl6a, Drer\zgc:171927, Drer\rab33ba, Drer\rab1bb, Drer\rab43" "Scer\TEM1, Scer\YPT1" "Cele\rab-35, Cele\rab-28" "Xtro\rabl6, Xtro\rab1a, Xtro\rab19, Xtro\rab33b, Xtro\rab33a, Xtro\rab28" "Mmus\Rab35, Mmus\Rab33b, Mmus\Rab28, Mmus\Rabl6, Mmus\Rab1a, Mmus\Rab1b, Mmus\Rab43, Mmus\Rab33a, Mmus\Rab19" "Hsap\RAB19, Hsap\RAB1A, Hsap\RABL6, Hsap\RAB28, Hsap\RAB35, Hsap\RAB33A, Hsap\RAB33B, Hsap\RAB1B, Hsap\RAB43" "viable,fertile" DRSC19853 K -0.173170085 -0.51929645 -0.432503261 0.179406866 -0.093187044 -1.988927987 FBgn0001082 Fum Fumarase http://flybase.org/reports/FBgn0001082 - gene fumarate hydratase activity ; GO:0004333 | inferred from direct assay - - "FUM, Fuh, Fum" - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0015572 alpha-Est4 alpha-Esterase-4 http://flybase.org/reports/FBgn0015572 - protein_coding_gene - - - "alphaE4, aE4, C, CG1082, alpha-Est4, DmalphaE4, FBgn0015572" "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG1082 11-Aug-17 DroID_v2017_08 "Drer\nlgn3a, Drer\cel.1, Drer\nlgn2a, Drer\nlgn4b, Drer\nlgn4a, Drer\nlgn1, Drer\ces3, Drer\ces2, Drer\nlgn2b, Drer\nlgn3b, Drer\cell, Drer\si:ch211-93f2.1" - "Cele\F56C11.6, Cele\T28C12.5, Cele\Y71H2AM.13, Cele\F13H6.3, Cele\T28C12.4, Cele\K11G9.3, Cele\K11G9.2, Cele\C01B10.10, Cele\R173.3, Cele\K11G9.1, Cele\F07C4.12, Cele\C52A10.1, Cele\B0238.1, Cele\B0238.7, Cele\C17H12.4, Cele\F15A8.6" "Xtro\cel, Xtro\ces3, Xtro\LOC100494782, Xtro\ces2, Xtro\nlgn4x, Xtro\nlgn3, Xtro\nlgn2" "Mmus\Ces1b, Mmus\Ces4a, Mmus\Nlgn3, Mmus\Ces2e, Mmus\Ces2a, Mmus\Ces5a, Mmus\Ces3a, Mmus\Ces1c, Mmus\Ces1g, Mmus\Ces2b, Mmus\Ces2g, Mmus\Bche, Mmus\Ces2c, Mmus\Cel, Mmus\Ces3b, Mmus\Ces2h, Mmus\Nlgn1, Mmus\Ces1d, Mmus\Ces2f, Mmus\Ces1h, Mmus\Ces1e, Mmus\Ces1f, Mmus\Nlgn2" "Hsap\NLGN1, Hsap\CES2, Hsap\NLGN4Y, Hsap\BCHE, Hsap\NLGN2, Hsap\NLGN4X, Hsap\NLGN3, Hsap\CES4A, Hsap\CES1, Hsap\CES3, Hsap\CEL, Hsap\CES5A" viable FBgn0003389 she sherry http://flybase.org/reports/FBgn0003389 - gene - - - she - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" pigment cell FBgn0264405 FCG-H - http://flybase.org/reports/FBgn0264405 gene - - - FCG-H - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0265651 CR44458 - http://flybase.org/reports/FBgn0265651 non_protein_coding_gene - - - "lincRNA.316, CR44458" - CR44458 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043475 micropia\gag micropia element gag http://flybase.org/reports/FBgn0043475 transposable_element_gene - - - micropia\gag - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036731 CG6333 - http://flybase.org/reports/FBgn0036731 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6333 - CG6333 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037085 Neu2 Neuroectoderm-expressed 2 http://flybase.org/reports/FBgn0037085 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG7204, Neu2" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG7204 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113e8.10, Drer\znf1014, Drer\LOC100535385, Drer\znf1008, Drer\LOC101885450, Drer\si:ch73-138e16.4, Drer\zgc:66443, Drer\LOC101886546, Drer\si:ch73-40a17.4, Drer\LOC103911751, Drer\LOC100332787, Drer\LOC101884416" "Scer\STP4, Scer\STP3, Scer\PZF1" Cele\zfp-2 - "Mmus\Zfp91, Mmus\Zfp7" "Hsap\ZNF7, Hsap\ZFP91" embryonic stage | stage 5 ventral neurogenic region | restricted

viable FBgn0062629 Mod(var)1025 Mod(var)1025 http://flybase.org/reports/FBgn0062629 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1025, Mod(var)1025" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0082970 snoRNA:Psi28S-3316c snoRNA:Psi28S-3316c http://flybase.org/reports/FBgn0082970 snoRNA_gene - - - "snoRNA:Psi28S-3316c, Psi28S-3316c, psi28S-3316c, CR34550" - CR34550 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030361 CG1492 - http://flybase.org/reports/FBgn0030361 protein_coding_gene glutathione hydrolase activity ; GO:0036374 | inferred from electronic annotation with InterPro:IPR000101 glutathione catabolic process ; GO:0006751 | inferred from electronic annotation with InterPro:IPR000101 - CG1492 "IPR000101:Gamma-glutamyltranspeptidase, IPR029055:Nucleophile aminohydrolases, N-terminal" CG1492 11-Aug-17 DroID_v2017_08 "Drer\ggt5a, Drer\ggt1a, Drer\si:ch73-236c18.3, Drer\si:dkey-222h21.12, Drer\si:ch73-59p9.2, Drer\ggt1l2.2, Drer\ggt1b, Drer\ggt5b" Scer\ECM38 "Cele\Y7A9A.1, Cele\Y97E10AR.2, Cele\H14N18.4, Cele\C53D5.5, Cele\T19H12.6, Cele\T03D8.6" "Xtro\ggt1, Xtro\ggt7, Xtro\ggt5" "Mmus\Ggt5, Mmus\Ggt7, Mmus\Ggt6, Mmus\Ggt1" "Hsap\GGTLC1, Hsap\GGTLC2, Hsap\GGT1, Hsap\GGT7, Hsap\GGT5, Hsap\GGT6, Hsap\GGT2" viable DRSC19605 E -0.182157153 -0.471713977 0.071032606 -2.206825679 -0.768534303 0.152363915 FBgn0067371 l(2)NC148 lethal (2) NC148 http://flybase.org/reports/FBgn0067371 gene - - - l(2)NC148 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052687 CG32687 - http://flybase.org/reports/FBgn0052687 protein_coding_gene - - - "CG2892, CG2143, CT7080, CT6984, BcDNA:RH29237, CG32687, Cg32687" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG32687 11-Aug-17 DroID_v2017_08 "Drer\lrrc58b, Drer\lrrc58a" - Cele\Y42G9A.3 Xtro\lrrc58 Mmus\Lrrc58 Hsap\LRRC58 viable FBgn0024640 l(2)k12702 lethal (2) k12702 http://flybase.org/reports/FBgn0024640 - gene - - - "127/2, l(2)k12702" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027119 l(?)rO127 lethal (?) rO127 http://flybase.org/reports/FBgn0027119 - gene - - - l(?)rO127 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022024 l(2)k08931 lethal (2) k08931 http://flybase.org/reports/FBgn0022024 - gene - - - l(2)k08931 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003466 sp speck http://flybase.org/reports/FBgn0003466 - gene - - - sp - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,body color defective" FBgn0035583 CG13704 - http://flybase.org/reports/FBgn0035583 protein_coding_gene - - - "BcDNA:RE40159, CG13704" - CG13704 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031176 CG1678 - http://flybase.org/reports/FBgn0031176 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "BcDNA:GH04760, CG1678" - CG1678 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0284256 bsf bicoid stability factor http://flybase.org/reports/FBgn0284256 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000755749 mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay endonuclease activity ; GO:0004519 | inferred from biological aspect of ancestor with PANTHER:PTN000755749 polycistronic mRNA processing ; GO:0031426 | inferred from mutant phenotype mitochondrial mRNA polyadenylation ; GO:0097222 | inferred from mutant phenotype regulation of mitochondrial mRNA stability ; GO:0044528 | inferred from mutant phenotype regulation of transcription from mitochondrial promoter ; GO:1903108 | inferred from mutant phenotype mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from mutant phenotype mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from mutant phenotype RNA modification ; GO:0009451 | inferred from biological aspect of ancestor with PANTHER:PTN000755749 mitochondrial respiratory chain complex III assembly ; GO:0034551 | inferred from mutant phenotype positive regulation of oxidative phosphorylation ; GO:1903862 | inferred from mutant phenotype regulation of mitochondrial translation ; GO:0070129 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN002368489 Z disc ; GO:0030018 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN002368489 mitochondrion ; GO:0005739 | inferred from direct assay H zone ; GO:0031673 | inferred from direct assay RNA cap binding complex ; GO:0034518 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "bsf, CG10302, BSF, DmLrpprc1, l(2)SH1181, l(2)SH2 1181" "IPR011990:Tetratricopeptide-like helical domain, IPR002885:Pentatricopeptide repeat" CG10302 11-Aug-17 DroID_v2017_08 Drer\lrpprc - "Cele\C04E6.11, Cele\mma-1" Xtro\lrpprc Mmus\Lrpprc Hsap\LRPPRC "viable,fertile" FBgn0025508 l(2)59ABb lethal (2) 59ABb http://flybase.org/reports/FBgn0025508 - gene - - - l(2)59ABb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267162 CR45602 - http://flybase.org/reports/FBgn0267162 non_protein_coding_gene - - - CR45602 - CR45602 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259164 CG42269 - http://flybase.org/reports/FBgn0259164 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 "CG6600, CG42269, CG6596" "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG42269 11-Aug-17 DroID_v2017_08 "Drer\LOC100334012, Drer\slc22a5, Drer\slc22a7b.2, Drer\slc22a21, Drer\sv2, Drer\slc22a7b.3, Drer\slc22a7b.1, Drer\LOC101884074, Drer\slc22a6l, Drer\oatx, Drer\zmp:0000001102, Drer\slc22a13, Drer\zgc:175176" "Scer\QDR1, Scer\DTR1, Scer\TPO2, Scer\GIT1, Scer\YHK8, Scer\PHO84, Scer\AQR1, Scer\FLR1, Scer\HXT9, Scer\QDR2, Scer\TPO1, Scer\TPO3, Scer\QDR3" "Cele\C06H5.6, Cele\B0252.3, Cele\ZK892.3, Cele\C46C2.2, Cele\T22F7.1, Cele\Y66D12A.13, Cele\C53B4.1, Cele\Y57G11C.23, Cele\oct-1, Cele\B0361.11, Cele\Y51A2D.18" Xtro\slc22a6 "Mmus\Slc22a21, Mmus\Slc22a20, Mmus\Slc22a29, Mmus\Svop, Mmus\Slc22a27, Mmus\Slc22a30, Mmus\Sv2c, Mmus\Slc22a14, Mmus\Slc22a26, Mmus\Slc22a2, Mmus\Slc22a23, Mmus\Slc22a6, Mmus\Slc22a19, Mmus\Slc22a8, Mmus\Slc22a22, Mmus\Slc22a16, Mmus\Slc22a5, Mmus\Slc22a4, Mmus\Slc22a7, Mmus\Slc22a28" "Hsap\SVOP, Hsap\SLC22A5, Hsap\SLC22A6, Hsap\SLC22A1, Hsap\SLC22A10, Hsap\SLC22A12, Hsap\SV2B, Hsap\SLC22A24, Hsap\SV2C, Hsap\SLC22A2, Hsap\SLC22A11, Hsap\SLC22A8, Hsap\SLC22A23, Hsap\SLC22A9, Hsap\SLC22A4, Hsap\SLC22A25, Hsap\SLC22A7" FBgn0003125 pop popeye http://flybase.org/reports/FBgn0003125 - gene - - - pop - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,viable,male,reduced,visible" "eye,ommatidium,wing" FBgn0020898 Su(osk)E2 Suppressor of oskar E2 http://flybase.org/reports/FBgn0020898 - gene - - - "E2, Su(osk)E2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000102 aperA abnormal proboscis extension reflex A http://flybase.org/reports/FBgn0000102 - gene - proboscis extension reflex ; GO:0007637 | inferred from mutant phenotype - aperA - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,recessive,behavior defective" FBgn0015416 l(1)15DFb lethal (1) 15DFb http://flybase.org/reports/FBgn0015416 - gene - - - l(1)15DFb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263004 CG43312 - http://flybase.org/reports/FBgn0263004 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43312 - CG43312 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051935 CG31935 - http://flybase.org/reports/FBgn0051935 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000484253 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with UniProtKB:Q15042 Rab GTPase binding ; GO:0017137 | inferred from sequence or structural similarity with UniProtKB:Q15042 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with HGNC:17063 regulation of Rab protein signal transduction ; GO:0032483 | inferred from sequence or structural similarity with UniProtKB:Q15042 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:17063 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with UniProtKB:Q80UJ7 regulation of calcium ion-dependent exocytosis of neurotransmitter ; GO:1903233 | inferred from sequence or structural similarity with UniProtKB:Q80UJ7 positive regulation of endoplasmic reticulum tubular network organization ; GO:1903373 | inferred from sequence or structural similarity with UniProtKB:Q15042 regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from sequence or structural similarity with UniProtKB:Q80UJ7 excitatory postsynaptic potential ; GO:0060079 | inferred from sequence or structural similarity with UniProtKB:Q80UJ7 lipid particle organization ; GO:0034389 | inferred from sequence or structural similarity with UniProtKB:Q15042 positive regulation of GTPase activity ; GO:0043547 | inferred from biological aspect of ancestor with PANTHER:PTN000484253 establishment of protein localization to endoplasmic reticulum membrane ; GO:0097051 | inferred from sequence or structural similarity with UniProtKB:Q15042 positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization ; GO:0061646 | inferred from sequence or structural similarity with UniProtKB:Q80UJ7 endoplasmic reticulum tubular network ; GO:0071782 | inferred from sequence or structural similarity with UniProtKB:Q15042 protein complex ; GO:0043234 | inferred from sequence or structural similarity with UniProtKB:Q15042 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000484253 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q15042 "CG7373, CG10870, CG31935" IPR026147:Rab3 GTPase-activating protein catalytic subunit CG31935 11-Aug-17 DroID_v2017_08 Drer\rab3gap1 - Cele\rbg-1 Xtro\rab3gap1 Mmus\Rab3gap1 Hsap\RAB3GAP1 "viable,fertile" DRSC00291 I 1.721827207 0.184901134 0.860447172 -0.404708244 -0.011526002 -0.205525264 FBgn0263096 CR43364 - http://flybase.org/reports/FBgn0263096 pseudogene_attribute - - - CR43364 - CR43364 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023091 dimm dimmed http://flybase.org/reports/FBgn0023091 FBgn0032942 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "neuroendocrine cell differentiation ; GO:0061101 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with cato positive regulation of peptide secretion ; GO:0002793 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype positive regulation of hormone secretion ; GO:0046887 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "c929, Dimm, CG8667, Mistr, dimm, DIMM, bHLHa16, dim" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8667 11-Aug-17 DroID_v2017_08 "Drer\neurod4, Drer\neurod2, Drer\neurod6a, Drer\neurod6b, Drer\neurod1, Drer\bhlha15" - Cele\cnd-1 "Xtro\neurod4, Xtro\bhlha15, Xtro\neurod6, Xtro\neurod1" "Mmus\Bhlha15, Mmus\Neurod4, Mmus\Neurod2, Mmus\Neurod6" "Hsap\NEUROD6, Hsap\NEUROD2, Hsap\NEUROD4, Hsap\BHLHA15, Hsap\NEUROD1" "viable,fertile,lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "eye photoreceptor cell,rhabdomereGMR.PU" FBgn0036515 AIMP2 aaRS-interacting multifunctional protein 2 http://flybase.org/reports/FBgn0036515 protein_coding_gene - - - "p38, CG12304, AIMP2" "IPR010987:Glutathione S-transferase, C-terminal-like" CG12304 11-Aug-17 DroID_v2017_08 Drer\aimp2 - - Xtro\aimp2 Mmus\Aimp2 Hsap\AIMP2 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0060642 l(3)S084101b lethal (3) S084101b http://flybase.org/reports/FBgn0060642 gene - - - "0841/01, l(3)S084101b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028022 l(3)S103909 lethal (3) S103909 http://flybase.org/reports/FBgn0028022 gene - - - "1039/09, l(3)S103909" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0039321 CG10550 - http://flybase.org/reports/FBgn0039321 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG10550 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG10550 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.8, Cele\C29F7.1, Cele\F59B1.10" - - - viable FBgn0265171 T:TM-shg Transmembrane domain of shg http://flybase.org/reports/FBgn0265171 engineered_tag - - - T:TM-shg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027139 l(3)87ABa lethal (3) 87ABa http://flybase.org/reports/FBgn0027139 - gene - - - l(3)87ABa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031102 CG15462 - http://flybase.org/reports/FBgn0031102 protein_coding_gene - - - CG15462 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030830 CG5172 - http://flybase.org/reports/FBgn0030830 protein_coding_gene - - - "CT16557, BcDNA:RH06401, CG5172" - CG5172 11-Aug-17 DroID_v2017_08 - - - - - - DRSC19936 I 0.294965684 2.200949359 0.528468348 0.249105804 -1.470969945 -0.774451201 FBgn0002888 mus202 mutagen-sensitive 202 http://flybase.org/reports/FBgn0002888 - gene - - - mus202 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,radiation sensitive" FBgn0038053 CG18549 - http://flybase.org/reports/FBgn0038053 protein_coding_gene - - - CG18549 "IPR020846:Major facilitator superfamily domain, IPR010291:Ion channel regulatory protein, UNC-93" CG18549 11-Aug-17 DroID_v2017_08 "Drer\LOC799265, Drer\mfsd11" - "Cele\C27C12.4, Cele\ZK6.8, Cele\F31D5.2, Cele\Y39D8A.1, Cele\B0554.7, Cele\C08D8.1, Cele\Y37A1A.2, Cele\ZK6.6, Cele\Y52E8A.6, Cele\F31D5.1, Cele\M153.2, Cele\Y39B6A.29, Cele\F36G9.3, Cele\Y39B6A.27, Cele\Y11D7A.3, Cele\B0554.5, Cele\plep-1" Xtro\mfsd11 "Mmus\Mettl23, Mmus\Mfsd11" Hsap\MFSD11 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0001490 l(1)10Ba lethal (1) 10Ba http://flybase.org/reports/FBgn0001490 - gene - - - "10Bc, l(1)GLM16, l(1)G16, l(1)10Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,polyphasic" FBgn0019795 l(1)100 lethal (1) 100 http://flybase.org/reports/FBgn0019795 - gene - - - l(1)100 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000094 Anp Andropin http://flybase.org/reports/FBgn0000094 - protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern response to bacterium ; GO:0009617 | traceable author statement positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria ; GO:0006965 | inferred from direct assay male-specific antibacterial humoral response ; GO:0006962 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "Anp, CEC, CG1361, Cec, And, k-9" IPR000875:Cecropin CG1361 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male ejaculatory duct

viable FBgn0011612 l(1)I33e27 lethal (1) I33e27 http://flybase.org/reports/FBgn0011612 FBgn0010206 gene - - - "l(1)33e27, l(1)I33e27" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260118 2L3120 - http://flybase.org/reports/FBgn0260118 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L3120 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0086658 snoRNA:Psi28S-1180 snoRNA:Psi28S-1180 http://flybase.org/reports/FBgn0086658 snoRNA_gene - - - "psi28s-1180, snoRNA:535, Psi 28S-1180(SnoR535), snoRNA:Psi28S-1180, Dm-535, snoR535, CR33661, chr2R:7107301..7107415" - CR33661 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017466 TfIIH-116 Transcription factor IIH-116kD http://flybase.net/reports/FBgn0017466.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TfIIH, TFIIH" 11-Aug-17 DroID_v2017_08 FBgn0263629 mir-3643 mir-3643 stem loop http://flybase.org/reports/FBgn0263629 miRNA_gene - - - "mir-3643, CR43509" - CR43509 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001680 l(1)ESHS1 lethal (1) ESHS1 http://flybase.org/reports/FBgn0001680 - gene - - - l(1)ESHS1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267253 CG32700 - http://flybase.org/reports/FBgn0267253 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32700, CG2994, CG12652, CG12651, CG18429, BcDNA:GH19985, Tes89, CR43497" - CG32700 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262736 Vha16-1 Vacuolar H[+] ATPase 16kD subunit 1 http://flybase.org/reports/FBgn0262736 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR002379, InterPro:IPR011555 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 dsRNA transport ; GO:0033227 | inferred from mutant phenotype lysosomal lumen acidification ; GO:0007042 | inferred from biological aspect of ancestor with PANTHER:PTN000813819 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" "plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000000753 fusome ; GO:0045169 | inferred from direct assay vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000813763" "CG3161, Vha16-1, vha16, V-ATPase, vha16-1, Vhac, EP2372, DucC, BcDNA:SD02875, Vha1, Vha16, MRE15, ATP6V0C" "IPR000245:V-ATPase proteolipid subunit, IPR002379:V-ATPase proteolipid subunit C-like domain, IPR011555:V-ATPase proteolipid subunit C, eukaryotic" CG3161 11-Aug-17 DroID_v2017_08 "Drer\atp6v0ca, Drer\atp6v0cb" "Scer\VMA11, Scer\VMA3" "Cele\vha-2, Cele\vha-3, Cele\vha-1" Xtro\atp6v0c Mmus\Atp6v0c Hsap\ATP6V0C DRSC05020 E -0.052804946 -0.120237927 0.748986477 -1.836981377 -0.163276801 -0.660154995 FBgn0264646 ichor ichor http://flybase.org/reports/FBgn0264646 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - "ichor, ichorous" - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0038752 CG4462 - http://flybase.org/reports/FBgn0038752 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG4462 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG4462 11-Aug-17 DroID_v2017_08 "Drer\slc22a5, Drer\LOC100334012, Drer\slc22a2, Drer\slc22a6l, Drer\slc22a4, Drer\slc22a7b.2, Drer\slc22a21, Drer\zgc:175176, Drer\zmp:0000001102, Drer\slc22a13, Drer\LOC101884074, Drer\oatx, Drer\slc22a7b.1, Drer\sv2, Drer\slc22a7b.3" "Scer\QDR1, Scer\QDR3, Scer\QDR2, Scer\TPO3, Scer\FLR1, Scer\TPO2, Scer\TPO1, Scer\DTR1, Scer\YHK8, Scer\AQR1" "Cele\K09E9.1, Cele\oct-2, Cele\T22F7.1" Xtro\slc22a6 "Mmus\Sv2c, Mmus\Slc22a3, Mmus\Slc22a19, Mmus\Svop, Mmus\Slc22a30, Mmus\Slc22a2, Mmus\Slc22a1, Mmus\Slc22a29, Mmus\Slc22a23, Mmus\Slc22a14, Mmus\Slc22a26, Mmus\Slc22a7, Mmus\Slc22a8, Mmus\Slc22a6, Mmus\Slc22a4, Mmus\Slc22a28, Mmus\Slc22a27, Mmus\Slc22a22, Mmus\Slc22a16, Mmus\Slc22a20" "Hsap\SV2B, Hsap\SLC22A24, Hsap\SV2C, Hsap\SLC22A9, Hsap\SLC22A25, Hsap\SLC22A23, Hsap\SLC22A3, Hsap\SLC22A11, Hsap\SLC22A10, Hsap\SLC22A6, Hsap\SLC22A1, Hsap\SLC22A7, Hsap\SLC22A12, Hsap\SLC22A8, Hsap\SLC22A2, Hsap\SVOP" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0084421 l(3)S090114 l(3)S090114 http://flybase.org/reports/FBgn0084421 gene - - - l(3)S090114 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004476 Exh Epoxide hydrolase http://flybase.org/reports/FBgn0004476 - gene epoxide hydrolase activity ; GO:0004301 | inferred from direct assay - intracellular membrane-bounded organelle ; GO:0043231 | inferred from direct assay "EH, Exh" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040559 CG14359 - http://flybase.org/reports/FBgn0040559 protein_coding_gene - - - CG14359 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC14822 K -0.100329697 -0.158764521 0.777055153 -0.306254371 -1.622359899 -0.618809154 FBgn0085428 Nox NADPH oxidase http://flybase.org/reports/FBgn0085428 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 superoxide-generating NADPH oxidase activity ; GO:0016175 | inferred from electronic annotation with InterPro:IPR029648 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR013112, InterPro:IPR013121, InterPro:IPR017927, InterPro:IPR017938 superoxide anion generation ; GO:0042554 | inferred from electronic annotation with InterPro:IPR029648 ovulation ; GO:0030728 | inferred from mutant phenotype positive regulation of smooth muscle contraction ; GO:0045987 | inferred from mutant phenotype positive regulation of calcium-mediated signaling ; GO:0050850 | inferred from mutant phenotype" - "CG34399, dNox, CG3896, Nox, CG15924, dnox, NOX-1, Nox1" "IPR013130:Ferric reductase transmembrane component-like domain, IPR013121:Ferric reductase, NAD binding domain, IPR013112:FAD-binding 8, IPR011992:EF-hand domain pair, IPR002048:EF-hand domain, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR018247:EF-Hand 1, calcium-binding site, IPR017938:Riboflavin synthase-like beta-barrel, IPR029648:NADPH oxidase 5" CG34399 11-Aug-17 DroID_v2017_08 "Drer\nox5, Drer\duox, Drer\nox1" "Scer\FRE6, Scer\FRE8, Scer\AIM14, Scer\FRE7, Scer\FRE4, Scer\FRE2, Scer\FRE5, Scer\FRE3, Scer\FRE1" - "Xtro\nox1, Xtro\duox1, Xtro\duox2, Xtro\cybb, Xtro\nox5" "Mmus\Cybb, Mmus\Nox1, Mmus\Nox3, Mmus\Duox1, Mmus\Duox2, Mmus\Nox4" "Hsap\NOX3, Hsap\NOX4, Hsap\NOX5, Hsap\DUOX1, Hsap\CYBB, Hsap\DUOX2, Hsap\NOX1" "viable,visible" trichogen cell DRSC06596 K 0.29095809 0.989383219 0.180497155 0.434073305 1.759216109 1.310402486 FBgn0069911 CR40475 - http://flybase.org/reports/FBgn0069911 non_protein_coding_gene - - - CR40475 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025624 CG4025 - http://flybase.org/reports/FBgn0025624 FBgn0044709 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of autophagy ; GO:0010506 | inferred from sequence or structural similarity with HGNC:25645 lysosome ; GO:0005764 | inferred from sequence or structural similarity with HGNC:25645 lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN001467492 "EG:22E5.9, anon-WO0140519.169, CG4025, DRAM" IPR019402:Frag1/DRAM/Sfk1 CG4025 11-Aug-17 DroID_v2017_08 "Drer\zgc:86738, Drer\LOC103911695, Drer\si:dkey-228d14.5, Drer\LOC792944, Drer\dram2b, Drer\zgc:154058, Drer\tmem150c, Drer\dram1, Drer\zgc:123244, Drer\tmem150aa, Drer\tmem150ab" Scer\SFK1 "Cele\C33A11.2, Cele\W03A5.2, Cele\F11E6.6" "Xtro\tmem150b, Xtro\tmem150a, Xtro\dram1" "Mmus\Tmem150a, Mmus\Tmem150c, Mmus\Dram1, Mmus\Tmem150b, Mmus\Dram2" "Hsap\DRAM2, Hsap\TMEM150B, Hsap\TMEM150C, Hsap\TMEM150A, Hsap\DRAM1" viable FBgn0261528 vainsE vainsE http://flybase.org/reports/FBgn0261528 protein_coding_gene - - - vainsE - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0261549 rdgA retinal degeneration A http://flybase.org/reports/FBgn0261549 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 diacylglycerol kinase activity ; GO:0004143 | non-traceable author statement diacylglycerol kinase activity ; GO:0004143 | inferred from sequence or structural similarity with Dgk diacylglycerol kinase activity ; GO:0004143 | traceable author statement protein kinase C-activating G-protein coupled receptor signaling pathway ; GO:0007205 | inferred from electronic annotation with InterPro:IPR000756 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 lipid phosphorylation ; GO:0046834 | traceable author statement rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype phosphatidic acid biosynthetic process ; GO:0006654 | traceable author statement phosphorylation ; GO:0016310 | non-traceable author statement rhodopsin metabolic process ; GO:0046154 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype phototransduction ; GO:0007602 | traceable author statement photoreceptor cell maintenance ; GO:0045494 | traceable author statement phototransduction ; GO:0007602 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from genetic interaction with trp thermotaxis ; GO:0043052 | inferred from direct assay phosphatidylinositol biosynthetic process ; GO:0006661 | traceable author statement sensory perception of sound ; GO:0007605 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "rdgA, CG42667, CG15352, CG34344, DGK, CG10966, dDGK2, DGK2, x35, CG12660, RDGA, dgk-5" "IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1, IPR000756:Diacylglycerol kinase, accessory domain, IPR002110:Ankyrin repeat, IPR001206:Diacylglycerol kinase, catalytic domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR020683:Ankyrin repeat-containing domain" CG42667 11-Aug-17 DroID_v2017_08 "Drer\dgki, Drer\dgkza, Drer\dgkzb" - "Cele\dgk-5, Cele\dgk-2" Xtro\dgkz "Mmus\Dgki, Mmus\Dgkz" "Hsap\DGKZ, Hsap\DGKI" adult stage " eye

, adult head

" FBgn0085085 C30 C30 http://flybase.org/reports/FBgn0085085 gene - - - C30 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0061124 l(3)S003831b lethal (3) S003831b http://flybase.org/reports/FBgn0061124 gene - - - "0038/31, l(3)S003831b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0003903 twt twirled tips http://flybase.org/reports/FBgn0003903 - gene - - - twt - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable,male,poor,visible" wing FBgn0024634 l(2)k13914 lethal (2) k13914 http://flybase.org/reports/FBgn0024634 - gene - - - "139/14, l(2)k13914" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036176 CG7377 - http://flybase.org/reports/FBgn0036176 protein_coding_gene - - - "HDC09644, CG7377" - CG7377 11-Aug-17 DroID_v2017_08 - - - - - - DRSC10830 K -0.451229146 -0.177714508 0.254978093 -0.060171851 1.60108159 0.08202611 FBgn0037677 CG12951 - http://flybase.org/reports/FBgn0037677 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP87, CG12951" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG12951 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001088, Drer\prss59.2, Drer\LOC103908930" - "Cele\svh-1, Cele\try-1" - "Mmus\Klk1b27, Mmus\Klk1b3, Mmus\Prss36, Mmus\Klk9, Mmus\Klk7, Mmus\Klk13, Mmus\Klk1b16, Mmus\Klk1b11, Mmus\Klk1b21, Mmus\Klk8, Mmus\Klk1, Mmus\Klk1b22, Mmus\Klk11, Mmus\Klk6, Mmus\Klk1b9, Mmus\Klk1b4, Mmus\Klk12, Mmus\Klk1b5, Mmus\Klk10, Mmus\Klk1b26, Mmus\Klk14, Mmus\Klk5, Mmus\Proz, Mmus\Prss53, Mmus\Egfbp2, Mmus\Klk1b24, Mmus\Klk1b8, Mmus\Klk15, Mmus\Mcpt8, Mmus\Klk4, Mmus\Klk1b1" "Hsap\KLK5, Hsap\CTSG, Hsap\CFD, Hsap\KLK7, Hsap\KLK15, Hsap\KLK1, Hsap\KLK10, Hsap\KLK8, Hsap\KLK12, Hsap\KLK3, Hsap\PRSS36, Hsap\PRSS53, Hsap\KLK11, Hsap\KLK6, Hsap\PRSS57, Hsap\KLK13, Hsap\KLK2, Hsap\PRSS48, Hsap\PROZ, Hsap\KLK14, Hsap\KLK4, Hsap\KLK9" viable FBgn0037844 CG4570 - http://flybase.org/reports/FBgn0037844 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002492 "transposition, DNA-mediated ; GO:0006313 | inferred from electronic annotation with InterPro:IPR002492 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR002492 developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN001124877" - CG4570 "IPR002492:Transposase, Tc1-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG4570 11-Aug-17 DroID_v2017_08 Drer\si:dkey-77f5.3 - Cele\F13B6.1 - - - viable DRSC15602 I 0.575526501 1.997074849 0.827526756 0.383149066 -0.453905845 0.23599162 FBgn0003293 rta reduced tarsi http://flybase.org/reports/FBgn0003293 - gene - - - rta - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male sterile,viable,poor" "eye,wing,macrochaeta,tarsal segment" FBgn0267320 CR45756 - http://flybase.org/reports/FBgn0267320 non_protein_coding_gene - - - "CR45756, lincRNA.587" - CR45756 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051943 tRNA:Gln-CTG-2-2 transfer RNA:Glutamine-CTG 2-2 http://flybase.org/reports/FBgn0051943 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002638.trna9-GlnCTG, tRNA:Q:CTG:AE002638-d, CR31943, chr2L.trna2-GlnCTG, tRNA:Gln-CTG-2-2, tRNA:CR31943, tRNA-Gln-CTG-2-2, CAG" - CR31943 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022980 rrpA reduced receptor potential A http://flybase.org/reports/FBgn0022980 - gene - - - rrpA - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013530 l(2)ry28 lethal (2) ry28 http://flybase.org/reports/FBgn0013530 - gene - - - "l(2)28, l(2)ry28" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085680 CG41545 - http://flybase.org/reports/FBgn0085680 protein_coding_gene - - - CG41545 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038079 NijC Ninjurin C http://flybase.org/reports/FBgn0038079 protein_coding_gene - tissue regeneration ; GO:0042246 | inferred from electronic annotation with InterPro:IPR007007 cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR007007 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007007 "NijC, CG14394" IPR007007:Ninjurin CG14394 11-Aug-17 DroID_v2017_08 "Drer\ninj2, Drer\si:ch1073-278o19.1" - - Xtro\ninj1 "Mmus\Ninj2, Mmus\Ninj1" "Hsap\NINJ2, Hsap\NINJ1" viable FBgn0033951 CG10139 - http://flybase.org/reports/FBgn0033951 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10139 - CG10139 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0042205 CG18764 - http://flybase.org/reports/FBgn0042205 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG18764 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG18764 11-Aug-17 DroID_v2017_08 "Drer\bcl6ab, Drer\znf408" Scer\AZF1 "Cele\lin-29, Cele\Y55F3AM.14, Cele\blmp-1, Cele\M03D4.4, Cele\ztf-23" - "Mmus\Rbak, Mmus\Zfp276, Mmus\Zfp110, Mmus\Zfp24, Mmus\Zfp445, Mmus\Zfp810, Mmus\Zscan5b, Mmus\Zfp369" "Hsap\ZNF3, Hsap\ZNF205, Hsap\ZNF621, Hsap\ZFP92, Hsap\ZNF773, Hsap\ZNF483, Hsap\ZNF662, Hsap\ZNF460, Hsap\ZNF2, Hsap\ZSCAN30, Hsap\ZKSCAN1, Hsap\ZSCAN23, Hsap\ZNF354C, Hsap\ZNF19, Hsap\ZNF140, Hsap\ZNF302, Hsap\ZNF514, Hsap\ZSCAN10, Hsap\ZNF18, Hsap\ZNF550, Hsap\ZNF496, Hsap\ZNF565, Hsap\ZKSCAN3, Hsap\ZNF75D, Hsap\ZKSCAN8, Hsap\ZNF620, Hsap\ZNF169, Hsap\ZSCAN1, Hsap\ZNF669, Hsap\MZF1, Hsap\ZNF202, Hsap\ZNF232, Hsap\ZKSCAN7, Hsap\ZNF684, Hsap\ZSCAN22, Hsap\ZNF701, Hsap\ZFP69B, Hsap\ZNF213, Hsap\ZNF582, Hsap\ZNF444, Hsap\ZNF383, Hsap\ZNF789, Hsap\ZNF735, Hsap\ZNF24, Hsap\ZNF517, Hsap\ZNF101, Hsap\ZNF736, Hsap\ZNF10, Hsap\ZNF806, Hsap\ZSCAN25, Hsap\ZNF197, Hsap\ZNF500, Hsap\ZNF554, Hsap\ZNF397, Hsap\ZNF557, Hsap\ZNF274, Hsap\ZKSCAN5, Hsap\ZKSCAN4, Hsap\ZNF276, Hsap\ZIM3, Hsap\ZNF584, Hsap\ZNF566, Hsap\ZNF574, Hsap\ZNF449, Hsap\ZNF8, Hsap\ZNF641, Hsap\ZFP69, Hsap\ZNF649, Hsap\ZNF124, Hsap\ZNF485, Hsap\ZNF560, Hsap\ZSCAN16, Hsap\ZNF506, Hsap\ZNF844, Hsap\ZNF577, Hsap\ZNF154, Hsap\ZNF263, Hsap\GZF1, Hsap\ZNF281, Hsap\ZSCAN31, Hsap\ZNF286A, Hsap\ZSCAN26, Hsap\ZNF285, Hsap\ZNF829, Hsap\ZNF547, Hsap\ZNF20, Hsap\ZSCAN12, Hsap\ZNF562, Hsap\ZNF396, Hsap\ZSCAN20, Hsap\ZSCAN21, Hsap\ZNF350" viable FBgn0038651 Epg5 ectopic P-granules autophagy protein 5 http://flybase.org/reports/FBgn0038651 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from biological aspect of ancestor with PANTHER:PTN001579556 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001579556 "Epg5, CG14299, epg5" IPR029651:Ectopic P granules protein 5 CG14299 11-Aug-17 DroID_v2017_08 Drer\epg5 - "Cele\epg-5, Cele\C56C10.11" Xtro\epg5 Mmus\Epg5 Hsap\EPG5 "viable,visible" chaeta DRSC14778 I -1.960208172 -0.179971839 -1.031354948 -0.216407363 0.299610992 -0.307584695 FBgn0000869 fs(1)M64 female sterile (1) M64 http://flybase.org/reports/FBgn0000869 - gene - - - fs(1)M64 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0001112 Gld Glucose dehydrogenase http://flybase.org/reports/FBgn0001112 - protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 pupal chitin-based cuticle development ; GO:0008364 | traceable author statement sperm storage ; GO:0046693 | inferred from mutant phenotype glucose metabolic process ; GO:0006006 | traceable author statement sperm storage ; GO:0046693 | traceable author statement" - "Go, gld, GDH, GLD, l(3)84Cg, CG1152, Gld, glucose dehydrogenase" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG1152 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH " larval stage--pupal stage , adult stage | male " ejaculatory duct

"viable,fertile,wild-type,lethal,electrophoretic variant,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0267408 AOX1 Aldehyde oxidase 1 http://flybase.org/reports/FBgn0267408 protein_coding_gene "electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001041 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR006058 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR016166 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR016208 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 xanthine dehydrogenase activity ; GO:0004854 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 pyridoxal oxidase activity ; GO:0004732 | inferred from direct assay inferred from mutant phenotype" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002346, InterPro:IPR002888, InterPro:IPR008274, InterPro:IPR016166, InterPro:IPR016208 pyridoxal metabolic process ; GO:0042817 | inferred from mutant phenotype xanthine catabolic process ; GO:0009115 | inferred from biological aspect of ancestor with PANTHER:PTN000225632" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 "AOX1, CG18522, CT42272, DmAO1, lpo, PO, Po, LPO" "IPR000674:Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR002346:Molybdopterin dehydrogenase, FAD-binding, IPR002888:[2Fe-2S]-binding, IPR005107:CO dehydrogenase flavoprotein, C-terminal, IPR006058:2Fe-2S ferredoxin, iron-sulphur binding site, IPR008274:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding, IPR016166:FAD-binding, type 2, IPR016169:CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR016208:Aldehyde oxidase/xanthine dehydrogenase, IPR012675:Beta-grasp domain, IPR016167:FAD-binding, type 2, subdomain 1" CG18522 11-Aug-17 DroID_v2017_08 "Drer\aox6, Drer\aox5, Drer\xdh" - "Cele\F15E6.6, Cele\gad-3, Cele\F55B11.1" Xtro\xdh "Mmus\Aox1, Mmus\Aox3, Mmus\Aox4, Mmus\Xdh, Mmus\Aox2" "Hsap\XDH, Hsap\AOX1" FBgn0263263 fus2 - http://flybase.org/reports/FBgn0263263 gene - gonad development ; GO:0008406 | inferred from mutant phenotype - fus2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "gonad,gonadal sheath proper primordium" FBgn0032810 CG13077 - http://flybase.org/reports/FBgn0032810 protein_coding_gene - - - CG13077 IPR006593:Cytochrome b561/ferric reductase transmembrane CG13077 11-Aug-17 DroID_v2017_08 "Drer\cyb561d2, Drer\cyb561d1" - - Xtro\cyb561d2 "Mmus\Cyb561d1, Mmus\Cyb561d2" "Hsap\CYB561D2, Hsap\CYB561D1" DRSC02181 K -1.386450746 0.270070209 0.882256616 -0.032382211 1.65907269 1.404041946 FBgn0040357 CG14624 - http://flybase.org/reports/FBgn0040357 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "EG:BACR42I17.9, BACR42I17.9, CG14624" - CG14624 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" DRSC25253 K 0.110635356 0.769433935 0.456507648 -0.003715191 0.460723883 1.728989613 FBgn0028421 Kap3 Kinesin associated protein 3 http://flybase.org/reports/FBgn0028421 protein_coding_gene kinesin binding ; GO:0019894 | inferred from electronic annotation with InterPro:IPR008658 protein binding ; GO:0005515 | inferred from physical interaction with Apc2 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity with NCBI_gi:861365 non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype anterograde axonal transport ; GO:0008089 | inferred from mutant phenotype establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with NCBI_gi:861365 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | NOT inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with NCBI_gi:861365 "CG11759, DmKap, KAP3, Kap, DmKAP, dKAP3, Kap3, KAP, kap3" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR008658:Kinesin-associated protein 3" CG11759 11-Aug-17 DroID_v2017_08 "Drer\kifap3a, Drer\kifap3b" - Cele\kap-1 Xtro\kifap3 Mmus\Kifap3 Hsap\KIFAP3 "uncoordinated,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,neurophysiology defective,auditory perception defective,neuroanatomy defective,lethal,female,locomotor behavior defective,viable" "Johnston's organ & scolopidial cilium,sensillum trichodeum of antennal segment 3,sensillum basiconicum of antennal segment 3,labellar taste bristle,cilium" FBgn0003488 sprw spread wings http://flybase.org/reports/FBgn0003488 - gene - - - "sprw, spr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female sterile" wing FBgn0013456 fs(2)neo4 fs(2)neo4 http://flybase.org/reports/FBgn0013456 - gene - - - fs(2)neo4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal,maternal effect" FBgn0065090 snmRNA:558 small non-messenger RNA 558 http://flybase.org/reports/FBgn0065090 non_protein_coding_gene - - - "Dm-558, snmRNA:558" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033996 CG11807 - http://flybase.org/reports/FBgn0033996 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 - - "CT14564, CG11807" "IPR001683:Phox homologous domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG11807 11-Aug-17 DroID_v2017_08 "Drer\snx24, Drer\snx22, Drer\sgk3, Drer\stk11ip, Drer\nisch" - Cele\F13E9.1 "Xtro\nisch, Xtro\stk11ip" "Mmus\Stk11ip, Mmus\Snx22, Mmus\Sgk3, Mmus\Snx24, Mmus\Nisch" "Hsap\SNX24, Hsap\SNX20, Hsap\SNX22, Hsap\C8orf44-SGK3, Hsap\NISCH, Hsap\STK11IP" viable FBgn0029746 CG15465 - http://flybase.org/reports/FBgn0029746 protein_coding_gene - - - "CG15465, CG15465/CG6775" IPR015943:WD40/YVTN repeat-like-containing domain CG15465 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0050411 CG30411 - http://flybase.org/reports/FBgn0050411 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE06996, CG30411" IPR031734:Transcription activator MBF2 CG30411 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039193 CG13613 - http://flybase.org/reports/FBgn0039193 protein_coding_gene - - - CG13613 IPR006631:Protein of unknown function DM4/12 CG13613 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051702 CG31702 - http://flybase.org/reports/FBgn0051702 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004343 RNA polymerase II C-terminal domain phosphoserine binding ; GO:1990269 | inferred from biological aspect of ancestor with PANTHER:PTN000319032 transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from biological aspect of ancestor with PANTHER:PTN000319032" histone modification ; GO:0016570 | inferred from electronic annotation with InterPro:IPR031102 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from electronic annotation with InterPro:IPR031102 Cdc73/Paf1 complex ; GO:0016593 | inferred from biological aspect of ancestor with PANTHER:PTN000319032 CG31702 "IPR004343:Plus-3 domain, IPR031102:RNA polymerase-associated protein Rtf1" CG31702 11-Aug-17 DroID_v2017_08 Drer\rtf1 Scer\RTF1 Cele\rtfo-1 Xtro\rtf1 Mmus\Rtf1 Hsap\RTF1 DRSC03687 I 0.090913164 -1.807668958 -0.666848206 -0.453463609 -0.374582422 0.093253773 FBgn0052463 Tengl2 Testis EndoG-Like 2 http://flybase.org/reports/FBgn0052463 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG17006, CG32463, Tengl2" "IPR018524:DNA/RNA non-specific endonuclease, active site, IPR001604:DNA/RNA non-specific endonuclease, IPR020821:Extracellular Endonuclease, subunit A" CG32463 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165i18.2, Drer\LOC100332173, Drer\si:dkey-85k7.10, Drer\si:ch211-133n4.4, Drer\zmp:0000000699, Drer\zgc:172339, Drer\endog, Drer\LOC103910196, Drer\LOC103909050, Drer\LOC100333474, Drer\zgc:158445" Scer\NUC1 Cele\cps-6 "Xtro\endog, Xtro\endod1, Xtro\exog" "Mmus\Endod1, Mmus\Endog, Mmus\Exog" "Hsap\EXOG, Hsap\ENDOG, Hsap\ENDOD1" "viable,visible" chaeta FBgn0023214 edl ETS-domain lacking http://flybase.org/reports/FBgn0023214 "FBgn0019696, FBgn0024241, FBgn0034373, FBgn0064196, FBgn0064197" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR003118 transcriptional repressor activity, RNA polymerase II transcription factor binding ; GO:0001191 | inferred from physical interaction with pnt protein binding ; GO:0005515 | inferred from physical interaction with aop inferred from physical interaction with pnt RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000218930" "regulation of Ras protein signal transduction ; GO:0046578 | inferred from physical interaction with aop inferred from physical interaction with pnt regulation of transcription, DNA-templated ; GO:0006355 | inferred from physical interaction with aop inferred from physical interaction with pnt embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype photoreceptor cell development ; GO:0042461 | inferred from mutant phenotype nuclear export ; GO:0051168 | inferred from direct assay sensory organ development ; GO:0007423 | inferred from mutant phenotype regulation of phosphorylation ; GO:0042325 | inferred from direct assay regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from expression pattern traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with pnt" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 "edl, CG15085, Mae, MAE, mae, edl/mae, l(2)k06602, Edl, EDL, anon-WO02077276.3, anon-WO02077276.2" "IPR003118:Pointed domain, IPR013761:Sterile alpha motif/pointed domain" CG15085 11-Aug-17 DroID_v2017_08 Drer\etv7 - - - - - " larval stage | third instar ," " eye disc | restricted

, chordotonal organ precursor cell | subset

" "lethal,recessive,neuroanatomy defective,visible,increased cell death" "denticle belt & embryonic abdominal segment 3,embryonic ventral epidermis & embryonic abdominal segment 1,embryonic ventral epidermis & embryonic abdominal segment 2,embryonic ventral epidermis & embryonic abdominal segment 3,embryonic ventral epidermis & embryonic abdominal segment 4,denticle belt & embryonic abdominal segment 1,denticle belt & embryonic abdominal segment 2,denticle belt & embryonic abdominal segment 4,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,presumptive embryonic/larval central nervous system,ommatidium,eye,eye photoreceptor cell,ommatidial precursor cluster,dorsal appendage,wing,eye disc,mesothoracic tergum,drug conditional" FBgn0039030 CG6660 - http://flybase.org/reports/FBgn0039030 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 CG6660 "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG6660 11-Aug-17 DroID_v2017_08 "Drer\hsd17b8, Drer\elovl5, Drer\elovl1a, Drer\elovl1b, Drer\elovl7a, Drer\elovl2, Drer\elovl7b, Drer\elovl4a, Drer\dhrs7, Drer\zgc:101858, Drer\elovl8b, Drer\elovl4b, Drer\elovl8a" "Scer\ELO1, Scer\ELO3, Scer\ELO2" "Cele\F28H7.2, Cele\elo-6, Cele\dhs-25, Cele\ZK829.1, Cele\dhs-11, Cele\Y47G6A.21, Cele\elo-1, Cele\C06E4.3, Cele\Y47G6A.22, Cele\F26D2.15, Cele\F25D1.5, Cele\dhs-14" "Xtro\dhrs7, Xtro\elovl1, Xtro\elovl5, Xtro\cbr4, Xtro\elovl7, Xtro\MGC79752, Xtro\hsd17b8, Xtro\elovl2" "Mmus\Cbr4, Mmus\Dhrs7, Mmus\Elovl7, Mmus\Elovl1, Mmus\Elovl2, Mmus\H2-Ke6, Mmus\Elovl5, Mmus\Elovl4" "Hsap\ELOVL2, Hsap\DHRS7, Hsap\ELOVL1, Hsap\ELOVL4, Hsap\ELOVL5, Hsap\CBR4, Hsap\HSD17B8, Hsap\ELOVL7" "viable,lethal - all die during larval stage" embryonic/larval spiracle | larval stage FBgn0011509 SrpRbeta Signal recognition particle receptor beta http://flybase.org/reports/FBgn0011509 "FBgn0011516, FBgn0028478, FBgn0053162" protein_coding_gene signal recognition particle binding ; GO:0005047 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from sequence or structural similarity signal recognition particle binding ; GO:0005047 | inferred from biological aspect of ancestor with PANTHER:PTN000449834 larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype SRP-dependent cotranslational protein targeting to membrane ; GO:0006614 | inferred from biological aspect of ancestor with PANTHER:PTN000449834 SRP-dependent cotranslational protein targeting to membrane ; GO:0006614 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay signal recognition particle receptor complex ; GO:0005785 | inferred from biological aspect of ancestor with PANTHER:PTN000449834 signal recognition particle receptor complex ; GO:0005785 | inferred from sequence or structural similarity "srpRbeta, Dm SRbeta, SRbeta, l(3)rK561, l(3)rL537, CG5950, BcDNA:GM04779, CG33162, SrpRbeta, Q9VSN9" "IPR019009:Signal recognition particle receptor, beta subunit, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG33162 11-Aug-17 DroID_v2017_08 "Drer\tfa, Drer\srprb, Drer\otomp, Drer\zgc:172271" Scer\SRP102 "Cele\R186.3, Cele\F54D5.4" "Xtro\tf, Xtro\srprb, Xtro\mfi2, Xtro\depdc5" "Mmus\Trf, Mmus\Srprb, Mmus\Mfi2, Mmus\Ltf, Mmus\1300017J02Rik" "Hsap\TF, Hsap\MELTF, Hsap\LTF, Hsap\SRPRB" "lethal,recessive,neuroanatomy defective" "ventral nerve cord,peripheral nervous system,lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous,embryonic/larval neuroblast,ganglion mother cell" FBgn0259229 CG42329 - http://flybase.org/reports/FBgn0259229 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - "CG14343, CG5156, CG42329, CT16503" "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG42329 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-7, Cele\oac-54, Cele\oac-46, Cele\oac-53, Cele\oac-32, Cele\oac-50, Cele\oac-5, Cele\oac-14, Cele\oac-9, Cele\nrf-6, Cele\oac-39, Cele\rhy-1, Cele\oac-31, Cele\oac-55, Cele\oac-3, Cele\oac-20, Cele\oac-6, Cele\ndg-4" Xtro\LOC101732251 Mmus\Oacyl - FBgn0000052 ade2 adenosine 2 http://flybase.org/reports/FBgn0000052 - protein_coding_gene phosphoribosylformylglycinamidine synthase activity ; GO:0004642 | inferred from sequence or structural similarity with SGD:S000003293 'de novo' IMP biosynthetic process ; GO:0006189 | inferred from electronic annotation with InterPro:IPR010073 purine nucleotide biosynthetic process ; GO:0006164 | inferred from sequence or structural similarity with SGD:S000003293 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003293 "153122_at, pym, CG9127, ade2, Ade2, Paics" "IPR010073:Phosphoribosylformylglycinamidine synthase, IPR010918:AIR synthase-related protein, C-terminal domain, IPR016188:PurM-like, N-terminal domain, IPR017926:Glutamine amidotransferase, IPR029062:Class I glutamine amidotransferase-like" CG9127 11-Aug-17 DroID_v2017_08 Drer\pfas Scer\ADE6 Cele\F10F2.2 Xtro\pfas Mmus\Pfas Hsap\PFAS "auxotroph,recessive,male sterile,visible,eye color defective,female sterile,viable,poor,lethal,male fertile,female fertile,melanotic necrosis,partially lethal - majority die,some die during pupal stage,increased cell death,lethal - all die before end of pupal stage" "wing vein,trichome of the posterior wing margin,macrochaeta,pigment cell,wing,posterior crossvein,ocellus pigment granule,dorsal row,ventral row,genitalia,wing disc" FBgn0024686 knax knobby axons http://flybase.org/reports/FBgn0024686 - gene molecular_function ; GO:0003674 | no biological data available Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available knax - - 11-Aug-17 DroID_v2017_08 - - - - - - viable Bolwig nerve FBgn0032390 dgt2 dim gamma-tubulin 2 http://flybase.org/reports/FBgn0032390 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with wac microtubule binding ; GO:0008017 | inferred from direct assay mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype HAUS complex ; GO:0070652 | colocalizes_with inferred from direct assay spindle ; GO:0005819 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay spindle ; GO:0005819 | colocalizes_with inferred from direct assay meiotic spindle ; GO:0072687 | inferred from direct assay protein complex ; GO:0043234 | inferred from direct assay inferred from genetic interaction with wac "Dgt2, dgt2, CG16969" - CG16969 11-Aug-17 DroID_v2017_08 - - - - - - DRSC02548 I 4.394329998 0.152605355 1.267882049 0.458646349 -0.520527722 -0.535886001 FBgn0014002 Pdi Protein disulfide isomerase http://flybase.org/reports/FBgn0014002 - protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 peptidyl-proline 4-dioxygenase activity ; GO:0031545 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001053176 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017937 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway ; GO:1902175 | inferred from biological aspect of ancestor with PANTHER:PTN001053176" endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay rough endoplasmic reticulum ; GO:0005791 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay spindle envelope ; GO:0070732 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay cell pole ; GO:0060187 | inferred from direct assay "PDI, CG6988, EP(3)1022, pdi, dpdi, Dpdi, Pdi" "IPR005788:Disulphide isomerase, IPR005792:Protein disulphide isomerase, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site" CG6988 11-Aug-17 DroID_v2017_08 "Drer\pdia3, Drer\txndc11, Drer\zgc:77086, Drer\pdia2, Drer\p4hb, Drer\zgc:136472, Drer\zgc:100906, Drer\pdia4" "Scer\PDI1, Scer\EUG1" "Cele\pdi-1, Cele\F42G8.7, Cele\pdi-2, Cele\pdi-3, Cele\C14B9.2" "Xtro\txndc9, Xtro\pdia2, Xtro\p4hb, Xtro\txndc11, Xtro\pdia4, Xtro\pdia3, Xtro\pdilt" "Mmus\Pdia2, Mmus\P4hb, Mmus\Txndc9, Mmus\Pdia4, Mmus\Txndc11, Mmus\Pdia3, Mmus\Pdilt, Mmus\Erp27" "Hsap\P4HB, Hsap\TXNDC11, Hsap\PDIA2, Hsap\PDIA4, Hsap\TXNDC9, Hsap\PDILT, Hsap\PDIA3, Hsap\ERP27" "lethal,viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0035046 ND-19 NADH dehydrogenase (ubiquinone) 19 kDa subunit http://flybase.org/reports/FBgn0035046 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P51970 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P51970" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P51970 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000331160 "CG3683, NDUFA8, RH23043p, NUPM, ND-19, Ndufa8" "IPR016680:NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8, IPR010625:CHCH" CG3683 11-Aug-17 DroID_v2017_08 Drer\ndufa8 - Cele\Y54F10AM.5 Xtro\ndufa8 Mmus\Ndufa8 Hsap\NDUFA8 "viable,visible" "trichogen cell,mitochondrionple.PF" FBgn0023468 anon-52Db anon-52Db http://flybase.org/reports/FBgn0023468 - gene - - - anon-52Db - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065909 l(2)SH0184 lethal (2) SH0184 http://flybase.org/reports/FBgn0065909 gene - - - "l(2)SH0184, l(2)SH2 0184" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065725 l(2)SH0562 lethal (2) SH0562 http://flybase.org/reports/FBgn0065725 gene - - - "l(2)SH0562, l(2)SH2 0562" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038369 Arpc3A "Actin-related protein 2/3 complex, subunit 3A" http://flybase.org/reports/FBgn0038369 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with HGNC:706 Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from sequence or structural similarity with HGNC:706 Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with HGNC:706 "CG4560, ARC-P21, Arpc3A, ARPC, Arpc3a" IPR007204:Actin-related protein 2/3 complex subunit 3 CG4560 11-Aug-17 DroID_v2017_08 Drer\arpc3 Scer\ARC18 Cele\arx-5 Xtro\arpc3 Mmus\Arpc3 Hsap\ARPC3 adult stage "viable,visible" "chaeta,supernumerary" FBgn0035630 CG10576 - http://flybase.org/reports/FBgn0035630 protein_coding_gene - - - "BEST:CK00496, CG10576" "IPR000994:Peptidase M24, IPR004545:PA2G4 family, IPR011991:Winged helix-turn-helix DNA-binding domain" CG10576 11-Aug-17 DroID_v2017_08 "Drer\pa2g4b, Drer\pa2g4a" "Scer\ARX1, Scer\MAP2" Cele\W08E12.7 Xtro\pa2g4 Mmus\Pa2g4 Hsap\PA2G4 "viable,fertile" presumptive embryonic/larval muscle system FBgn0051324 CG31324 - http://flybase.org/reports/FBgn0051324 protein_coding_gene - - - "CG14557, BcDNA:RH68619, CG14555, CG31324" - CG31324 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001995 mRpL4 mitochondrial ribosomal protein L4 http://flybase.org/reports/FBgn0001995 FBgn0032584 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000078778 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049635 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049635 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity cytosolic ribosome ; GO:0022626 | inferred from biological aspect of ancestor with PANTHER:PTN000078778 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049635 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity "l(2)35Fe, L4, Rpl4, BG:DS02740.17, l(2)k14608, l35Fe, CG5818, mRpL4, mrpL4" "IPR002136:Ribosomal protein L4/L1e, IPR013005:50S ribosomal protein uL4, IPR023574:Ribosomal protein L4 domain" CG5818 11-Aug-17 DroID_v2017_08 Drer\mrpl4 Scer\YML6 Cele\mrpl-4 Xtro\mrpl4 Mmus\Mrpl4 Hsap\MRPL4 "lethal,recessive,visible,somatic clone,mitotic cell cycle defective,viable" "eye,somatic clone,eye disc,lens" FBgn0058130 CG40130 - http://flybase.org/reports/FBgn0058130 protein_coding_gene - - - CG40130 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260344 GSd441 - http://flybase.org/reports/FBgn0260344 gene - - - GSd441 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037250 CG1074 - http://flybase.org/reports/FBgn0037250 protein_coding_gene "methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR002052, InterPro:IPR016691 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002052" methylation ; GO:0032259 | inferred from electronic annotation with InterPro:IPR002052 - "anon-WO0118547.308, CG1074" "IPR000241:Putative RNA methylase domain, IPR002052:DNA methylase, N-6 adenine-specific, conserved site, IPR016691:tRNA guanosine-2'-O-methyltransferase, TRM11, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG1074 11-Aug-17 DroID_v2017_08 Drer\trmt11 Scer\TRM11 Cele\Y71F9AL.1 Xtro\trmt11 Mmus\Trmt11 Hsap\TRMT11 viable FBgn0025138 su(RpII140[Z36])S1 su(RpII140[Z36])S1 http://flybase.org/reports/FBgn0025138 - gene - - - "Z36[S1], su(RpII140[Z36])S1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265514 E(comt[6])E32 - http://flybase.org/reports/FBgn0265514 gene - - - E(comt[6])E32 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037385 glob3 globin 3 http://flybase.org/reports/FBgn0037385 protein_coding_gene "oxygen binding ; GO:0019825 | inferred from electronic annotation with InterPro:IPR000971, InterPro:IPR012292 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR000971, InterPro:IPR012292 heme binding ; GO:0020037 | inferred from sequence model oxygen binding ; GO:0019825 | inferred from sequence model" - cytoplasm ; GO:0005737 | inferred from sequence model "glob3, CG14675, DmeGb3, GLOB3" "IPR009050:Globin-like, IPR000971:Globin" CG14675 11-Aug-17 DroID_v2017_08 - - - Xtro\hba3 - Hsap\MB "viable,fertile" FBgn0001397 l(1)2Dg lethal (1) 2Dg http://flybase.org/reports/FBgn0001397 - gene - - - "l(1)90, N3, l(1)N3, l(1)2Dg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062536 anon-5187 anon-5187 http://flybase.org/reports/FBgn0062536 gene - - - "5187, anon-5187" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003604 Su(var)3-13 Suppressor of variegation 3-13 http://flybase.org/reports/FBgn0003604 - gene - - - "Su-var(3)13, Su(var)3-13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,lethal,recessive" FBgn0034869 CG13558 - http://flybase.org/reports/FBgn0034869 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13558 - CG13558 11-Aug-17 DroID_v2017_08 - - - - - - DRSC04196 K 0.089536904 -0.08729302 0.053414725 0.260902088 0.045184435 1.529522059 FBgn0002571 Mal-A3 Maltase A3 http://flybase.org/reports/FBgn0002571 - protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "L, V, CG8695, Mal-A3, mal_A3, LvpL, lvpL, Drome_A3" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG8695 11-Aug-17 DroID_v2017_08 "Drer\slc3a2b, Drer\slc3a1, Drer\zgc:158423, Drer\si:dkey-202g17.3, Drer\slc3a2a" "Scer\IMA1, Scer\MAL12, Scer\IMA3, Scer\MAL32, Scer\IMA4, Scer\IMA2, Scer\IMA5" "Cele\atgp-2, Cele\atgp-1" "Xtro\slc3a1, Xtro\slc3a2" "Mmus\Slc3a1, Mmus\Slc3a2" "Hsap\SLC3A1, Hsap\SLC3A2" " larval stage | early third instar larval stage , adult stage , larval stage | first instar , larval stage | second instar " organism

viable FBgn0000979 fs(2)HO192 female sterile (2) HO192 http://flybase.org/reports/FBgn0000979 - gene - - - "fs(2)192A, fs(2)HO192" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" ovary FBgn0265211 fs(2)Z2-965 - http://flybase.org/reports/FBgn0265211 gene - - - fs(2)Z2-965 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0011266 srh short rhabdomeres http://flybase.org/reports/FBgn0011266 - gene - - - srh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050449 tRNA:Glu-CTC-5-1Psi transfer RNA:Glutamic acid-CTC 5-1 pseudogene http://flybase.org/reports/FBgn0050449 pseudogene_attribute - - - "CR30221, CR30449, chr2R.trna39-GluCTC, tRNA:Glu-CTC-5-1Psi, tRNA:CR30449, tRNA-Glu-CTC-5-1" - CR30449 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013485 l(1)5P4 lethal (1) 5P4 http://flybase.org/reports/FBgn0013485 - gene - - - l(1)5P4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0259954 CG42464 - http://flybase.org/reports/FBgn0259954 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG42464 "IPR020901:Proteinase inhibitor I2, Kunitz, conserved site, IPR002223:Pancreatic trypsin inhibitor Kunitz domain" CG42464 11-Aug-17 DroID_v2017_08 "Drer\wfikkn1, Drer\tfpia, Drer\si:dkeyp-73b11.8, Drer\wfikkn2b, Drer\tfpi2, Drer\si:dkey-117n7.5, Drer\spint1b, Drer\spint1a, Drer\ambp, Drer\wfikkn2a, Drer\col6a4a, Drer\spint2" - "Cele\mlt-11, Cele\T22F7.5" "Xtro\tfpi2, Xtro\ambp, Xtro\spint2, Xtro\spint1" "Mmus\Ambp, Mmus\Spint2, Mmus\Spint4, Mmus\Wfdc6b, Mmus\Tfpi, Mmus\Wfdc6a, Mmus\Spint5, Mmus\Tfpi2, Mmus\Spint3, Mmus\Eppin, Mmus\Wfikkn2, Mmus\Spint1, Mmus\Wfdc8, Mmus\Wfikkn1" "Hsap\TFPI, Hsap\SPINT2, Hsap\EPPIN-WFDC6, Hsap\SPINT3, Hsap\WFIKKN1, Hsap\WFIKKN2, Hsap\SPINT1, Hsap\SPINT4, Hsap\TFPI2, Hsap\WFDC8, Hsap\WFDC6, Hsap\AMBP" FBgn0024865 l(3)04836 lethal (3) 04836 http://flybase.org/reports/FBgn0024865 - gene - - - "4836, l(3)04836" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065877 l(2)SH0240 lethal (2) SH0240 http://flybase.org/reports/FBgn0065877 gene - - - "l(2)SH0240, l(2)SH2 0240" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259270 C832 - http://flybase.org/reports/FBgn0259270 gene - - - C832 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0020662 E(spl)m8-HLH::E(spl)m5-HLH - http://flybase.org/reports/FBgn0020662 - engineered_fusion_gene - - - "E(spl)m8-HLH::E(spl)m5-HLH, E(spl)::E(spl)m5-HLH, E(spl)::HLHm5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259437 EP-207 - http://flybase.org/reports/FBgn0259437 gene - - - EP-207 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing hair,wing margin,chaeta,ectopic" FBgn0051224 CG31224 - http://flybase.org/reports/FBgn0051224 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG7696, l(3)c00083, CG17796, CG31224" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG31224 11-Aug-17 DroID_v2017_08 "Drer\znf618, Drer\zbtb44, Drer\si:dkey-66i24.8, Drer\LOC101886047" - "Cele\C28G1.4, Cele\Y5F2A.4, Cele\Y55F3AM.14, Cele\Y48G8AL.10" - "Mmus\Fiz1, Mmus\Zfp618, Mmus\Zbtb44, Mmus\Zfp579" "Hsap\FIZ1, Hsap\ZBTB44, Hsap\ZNF579, Hsap\ZNF618" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" DRSC16290 K -0.531553635 -0.13698214 0.488603924 1.492804615 -1.858871294 -0.89770294 FBgn0046660 anon-38C.45 anon-38C.45 http://flybase.org/reports/FBgn0046660 gene - - - "38C.45, anon-38C.45" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060789 l(3)S059403 lethal (3) S059403 http://flybase.org/reports/FBgn0060789 gene - - - "0594/03, l(3)S059403" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014937 anon-92Ec anon-92Ec http://flybase.org/reports/FBgn0014937 - gene - - - "mic, anon-92Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085234 CG34205 - http://flybase.org/reports/FBgn0085234 protein_coding_gene - - - "CG34205, CG13504" - CG34205 11-Aug-17 DroID_v2017_08 Drer\pou2af1 - - - Mmus\Pou2af1 Hsap\POU2AF1 FBgn0060317 l(3)S147406a lethal (3) S147406a http://flybase.org/reports/FBgn0060317 gene - - - "l(3)s147406, 1474/06, l(3)S147406a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0065251 l(2)SH2120 lethal (2) SH2120 http://flybase.org/reports/FBgn0065251 gene - - - "l(2)SH2120, l(2)SH2 2120" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026013 WC1 WC1 http://flybase.org/reports/FBgn0026013 - gene - - - "1(1)WC1, WC1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic epidermis,embryonic head" FBgn0065241 l(2)SH2154 lethal (2) SH2154 http://flybase.org/reports/FBgn0065241 gene - - - "l(2)SH2154, l(2)SH2 2154" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260935 Vps15 Vacuolar protein sorting 15 http://flybase.org/reports/FBgn0260935 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000426471 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with SGD:S000000301" protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000426471 pexophagy ; GO:0030242 | inferred from biological aspect of ancestor with PANTHER:PTN000426471 macroautophagy ; GO:0016236 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000000301 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype protein targeting to vacuole ; GO:0006623 | inferred from biological aspect of ancestor with PANTHER:PTN000426471 regulation of antimicrobial peptide production ; GO:0002784 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype late endosome to vacuole transport ; GO:0045324 | inferred from biological aspect of ancestor with PANTHER:PTN000426471 autophagy ; GO:0006914 | inferred from mutant phenotype inferred from genetic interaction with Pi3K59F "late endosome ; GO:0005770 | inferred from biological aspect of ancestor with PANTHER:PTN000426471 nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN000426471 nucleus-vacuole junction ; GO:0071561 | inferred from biological aspect of ancestor with PANTHER:PTN000426471 phosphatidylinositol 3-kinase complex, class III, type I ; GO:0034271 | inferred from direct assay phosphatidylinositol 3-kinase complex, class III, type II ; GO:0034272 | inferred from biological aspect of ancestor with PANTHER:PTN000426471" "Vps15, ird1, CG9746, vps15, ird, Ird1, dVps15/p150, dVps15" "IPR000719:Protein kinase domain, IPR001680:WD40 repeat, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR016024:Armadillo-type fold, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011989:Armadillo-like helical" CG9746 11-Aug-17 DroID_v2017_08 Drer\pik3r4 Scer\VPS15 Cele\vps-15 Xtro\pik3r4 Mmus\Pik3r4 Hsap\PIK3R4 FBgn0266593 CR45118 - http://flybase.org/reports/FBgn0266593 non_protein_coding_gene - - - CR45118 - CR45118 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262531 CG43085 - http://flybase.org/reports/FBgn0262531 protein_coding_gene - - - CG43085 - CG43085 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024706 anon-84Ab anon-84Ab http://flybase.org/reports/FBgn0024706 - gene - - - anon-84Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028074 l(3)S088501a lethal (3) S088501a http://flybase.org/reports/FBgn0028074 gene - - - "0885/01, l(3)S088501, l(3)S088501a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032551 CG18636 - http://flybase.org/reports/FBgn0032551 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH130, CG18636" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan" CG18636 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.12, Drer\si:ch211-165b19.5, Drer\si:dkey-21e2.15, Drer\gzm3, Drer\si:dkey-21e2.7, Drer\si:ch211-165b19.9" - Cele\try-3 - "Mmus\Mcpt1, Mmus\Klk1b9, Mmus\Egfbp2, Mmus\Gzmf, Mmus\Klk1b5, Mmus\Klk6, Mmus\Ctsg, Mmus\Gzmg, Mmus\Gzme, Mmus\Cma2, Mmus\Gzmb, Mmus\Cma1, Mmus\Gzmd, Mmus\Gzmc, Mmus\Mcpt9, Mmus\Mcpt4, Mmus\Mcpt8" "Hsap\CTSG, Hsap\GZMB, Hsap\CMA1, Hsap\GZMH" FBgn0029881 pigs pickled eggs http://flybase.org/reports/FBgn0029881 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR003108 ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype actin cytoskeleton ; GO:0015629 | colocalizes_with inferred from direct assay cytoplasmic microtubule ; GO:0005881 | colocalizes_with inferred from direct assay "CG3973, pigs" "IPR001715:Calponin homology domain, IPR003108:Gas2-related domain" CG3973 11-Aug-17 DroID_v2017_08 "Drer\gas2l2, Drer\flna, Drer\flnbl, Drer\gas2b, Drer\gas2, Drer\flncb, Drer\gas2l1, Drer\flnca, Drer\gas2l3" - "Cele\anc-1, Cele\D2096.11" "Xtro\gas2l1, Xtro\gas2l2" "Mmus\Flnb, Mmus\Gas2l2, Mmus\Gas2, Mmus\Gas2l1, Mmus\Flna, Mmus\Flnc, Mmus\Gas2l3" "Hsap\FLNC, Hsap\GAS2, Hsap\FLNA, Hsap\GAS2L1, Hsap\GAS2L2, Hsap\FLNB, Hsap\GAS2L3" "viable,flightless,partially lethal - majority live,female sterile,fertile" "indirect flight muscle,ovary,interfollicle cell,female germline stem cell,supernumerary,nurse cell ring canal,germarium,egg chamber,somatic clone,polar follicle cell,germarium cap cell,follicle cell" FBgn0024619 meso4 meso4 http://flybase.org/reports/FBgn0024619 FBgn0024479 gene - - - "Clone4, meso4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037891 CG5214 - http://flybase.org/reports/FBgn0037891 protein_coding_gene dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149 | inferred from sequence or structural similarity with UniProtKB:P36957 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P36957 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype cellular respiration ; GO:0045333 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial oxoglutarate dehydrogenase complex ; GO:0009353 | inferred from sequence or structural similarity with UniProtKB:P36957 lipid particle ; GO:0005811 | inferred from direct assay "CG5214, alpha-KGDHC" "IPR000089:Biotin/lipoyl attachment, IPR001078:2-oxoacid dehydrogenase acyltransferase, catalytic domain, IPR003016:2-oxo acid dehydrogenase, lipoyl-binding site, IPR006255:Dihydrolipoamide succinyltransferase, IPR011053:Single hybrid motif" CG5214 11-Aug-17 DroID_v2017_08 Drer\dlst Scer\KGD2 "Cele\dlst-1, Cele\C30H6.7" Xtro\dlst Mmus\Dlst Hsap\DLST "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0028042 l(3)S098916 lethal (3) S098916 http://flybase.org/reports/FBgn0028042 gene - - - "0989/16, l(3)S098916" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0026409 Mpcp Mitochondrial phosphate carrier protein http://flybase.org/reports/FBgn0026409 FBgn0010721 protein_coding_gene phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from sequence or structural similarity with UniProtKB:Q00325 phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from biological aspect of ancestor with PANTHER:PTN000639943 phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from sequence or structural similarity "phosphate ion transport ; GO:0006817 | inferred from sequence or structural similarity phosphate ion transport ; GO:0006817 | inferred from sequence or structural similarity with UniProtKB:Q00325 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity with UniProtKB:Q00325 lipid particle ; GO:0005811 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG4994, MPCP, PpsM, l(3)00564, Mpcp, Mcpc" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG4994 11-Aug-17 DroID_v2017_08 "Drer\slc25a3a, Drer\slc25a3b" "Scer\PIC2, Scer\MIR1" "Cele\T05F1.8, Cele\C33F10.12, Cele\F01G4.6, Cele\C14C10.1" Xtro\slc25a3 Mmus\Slc25a3 Hsap\SLC25A3 "lethal,recessive,viable,visible" "mesothoracic leg sensillum,metathoracic leg sensillum,prothoracic leg sensillum,antennal sense organ,trichogen cell" FBgn0037260 Mur82C Mucin related 82C http://flybase.org/reports/FBgn0037260 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from biological aspect of ancestor with PANTHER:PTN001977669 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model biological_process ; GO:0008150 | no biological data available extracellular matrix ; GO:0031012 | inferred from sequence model "Mur82C, CG12586" - CG12586 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC12011 IE -0.952939843 -2.369737312 -0.526836068 -4.952584323 -0.347196467 -0.336546737 FBgn0000681 flrdD flight reduced D http://flybase.org/reports/FBgn0000681 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdD - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,cold sensitive,jumping defective,flight defective" FBgn0065169 l(3)SH029 lethal (3) SH029 http://flybase.org/reports/FBgn0065169 gene - - - "l(3)SH029, l(2)SH3 029" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264719 CR43987 - http://flybase.org/reports/FBgn0264719 non_protein_coding_gene - - - "CR43987, lincRNA.612" - CR43987 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001871 l(1)Xi08 lethal (1) Xi08 http://flybase.org/reports/FBgn0001871 - gene - - - l(1)Xi08 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250825 CG34241 - http://flybase.org/reports/FBgn0250825 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34241, NEST:bs31h06, NEST:bs29g03, NEST:bs11f11" - CG34241 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262368 mir-282 mir-282 stem loop http://flybase.org/reports/FBgn0262368 miRNA_gene - "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" - "miR-282, mir-282, dme-mir-282, 282, MIR-282, CR42880, mir282, CR33598, dme-mir-276a, mir-282-RA, miR282, dme-miR-282" - CR42880 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,partially lethal - majority die,short lived,female semi-sterile,female fertile,germline clone,lethal - all die during second instar larval stage,lethal" "wing vein,ectopic,germarium" FBgn0010406 RNaseX25 Ribonuclease X25 http://flybase.org/reports/FBgn0010406 "FBtr0076752, FBpp0076469" protein_coding_gene "ribonuclease T2 activity ; GO:0033897 | inferred from electronic annotation with InterPro:IPR001568, InterPro:IPR018188 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001568, InterPro:IPR018188 ribonuclease activity ; GO:0004540 | inferred from sequence or structural similarity" multicellular organism reproduction ; GO:0032504 | inferred from expression pattern RNA catabolic process ; GO:0006401 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from sequence model "CG8194, DmRNase-X25, DmRNase-66B, RNaseX25, RNase X25" "IPR001568:Ribonuclease T2-like, IPR033130:Ribonuclease T2, His active site 2, IPR033697:Ribonuclease T2, eukaryotic" CG8194 11-Aug-17 DroID_v2017_08 "Drer\rnaset2l, Drer\rnaset2" Scer\RNY1 Cele\K10C9.3 Xtro\rnaset2 "Mmus\Gm1604b, Mmus\Rnaset2b, Mmus\Rnaset2a" Hsap\RNASET2 viable FBgn0065969 l(2)SH0006 lethal (2) SH0006 http://flybase.org/reports/FBgn0065969 gene - - - "l(2)SH0006, l(2)SH2 0006" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039010 CG4907 - http://flybase.org/reports/FBgn0039010 protein_coding_gene mannose-ethanolamine phosphotransferase activity ; GO:0051377 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 CG4907 "IPR007070:GPI ethanolamine phosphate transferase 1, IPR017850:Alkaline-phosphatase-like, core domain, IPR017852:GPI ethanolamine phosphate transferase 1, C-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG4907 11-Aug-17 DroID_v2017_08 Drer\pign Scer\MCD4 Cele\Y54E10BR.1 - Mmus\Pign Hsap\PIGN viable FBgn0053354 5SrRNA:CR33354 5SrRNA:CR33354 http://flybase.org/reports/FBgn0053354 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33354, 5SrRNA:CR33354" - CR33354 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265141 Ir47b Ionotropic receptor 47b http://flybase.org/reports/FBgn0265141 pseudogene_attribute - - - "Ir47b, DmelIR47b, CR44210" - CR44210 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014126 ax axed on 2 http://flybase.org/reports/FBgn0014126 - gene - - - ax - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" thorax FBgn0005343 Rst(1)mth Resistance to malathion http://flybase.org/reports/FBgn0005343 - gene - - - Rst(1)mth - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004760 l(3)89Ca lethal (3) 89Ca http://flybase.org/reports/FBgn0004760 - gene - - - l(3)89Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033210 U2A U2A http://flybase.org/reports/FBgn0033210 protein_coding_gene U2 snRNA binding ; GO:0030620 | inferred from biological aspect of ancestor with PANTHER:PTN000058203 "chromatin organization ; GO:0006325 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000006134 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000058203 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 spermatogenesis ; GO:0007283 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000058203 precatalytic spliceosome ; GO:0071011 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000006134 "U2A', l(2)43Ee, dU2A', CG1406, BcDNA:RE56869, U2A, u2a, U2A-prime" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG1406 11-Aug-17 DroID_v2017_08 "Drer\lrrc51, Drer\c13h10orf11, Drer\snrpa1" Scer\LEA1 Cele\mog-2 "Xtro\lrtomt, Xtro\c10orf11, Xtro\lrrc9, Xtro\snrpa1" "Mmus\1700112E06Rik, Mmus\Snrpa1, Mmus\Lrrc9, Mmus\Lrrc51" "Hsap\SNRPA1, Hsap\LRRC6, Hsap\C10orf11" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0020831 l(2)PW27 lethal (2) PW27 http://flybase.org/reports/FBgn0020831 - gene - - - "l(2)PW#27, l(2)PW27" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060901 l(3)S044006 lethal (3) S044006 http://flybase.org/reports/FBgn0060901 gene - - - "440/6, 0440/06, l(3)S044006" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0002058 l(2)40Fc lethal (2) 40Fc http://flybase.org/reports/FBgn0002058 - gene - - - "40Fc, l(2Lh)Fc, GroupVIII, l(2)EMS40-2, l(2)EMS40-01, l(2)40Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,recessive" "eye,wing" FBgn0267986 CR46253 - http://flybase.org/reports/FBgn0267986 non_protein_coding_gene - - - CR46253 - CR46253 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265041 CG44158 - http://flybase.org/reports/FBgn0265041 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44158 - CG44158 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032153 CG4537 - http://flybase.org/reports/FBgn0032153 protein_coding_gene PDZ domain binding ; GO:0030165 | inferred from sequence or structural similarity with RGD:621545 cytoplasmic microtubule organization ; GO:0031122 | inferred from sequence or structural similarity with RGD:621545 dendrite ; GO:0030425 | inferred from sequence or structural similarity with RGD:621545 CG4537 "IPR019367:PDZ-binding protein, CRIPT" CG4537 11-Aug-17 DroID_v2017_08 Drer\cript - Cele\C36B1.14 Xtro\cript Mmus\Cript Hsap\CRIPT FBgn0029663 CG10804 - http://flybase.org/reports/FBgn0029663 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT neurotransmitter transport ; GO:0006836 | inferred from sequence model transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 CG10804 IPR000175:Sodium:neurotransmitter symporter CG10804 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-132b12.1, Drer\slc6a15, Drer\slc6a14, Drer\slc6a13, Drer\slc6a1a, Drer\si:ch211-132b12.2, Drer\slc6a19a.2, Drer\slc6a13l, Drer\slc6a8, Drer\slc6a19b, Drer\slc6a9, Drer\slc6a16a, Drer\slc6a5, Drer\slc6a18, Drer\slc6a19a.1, Drer\slc6a2, Drer\slc6a1l, Drer\slc6a1b, Drer\slc6a13, Drer\zgc:158225, Drer\slc6a6a, Drer\slc6a16b, Drer\slc6a4b, Drer\slc6a6b, Drer\si:ch211-117c9.5, Drer\slc6a11a, Drer\slc6a17, Drer\slc6a4a, Drer\si:ch211-132b12.6" - "Cele\snf-3, Cele\snf-6, Cele\dat-1, Cele\mod-5, Cele\snf-11" "Xtro\slc6a19, Xtro\slc6a2, Xtro\slc6a4, Xtro\slc6a9, Xtro\slc6a16, Xtro\slc6a1, Xtro\slc6a8, Xtro\slc6a14.2, Xtro\slc6a12, Xtro\LOC100127682, Xtro\slc6a6, Xtro\slc6a13, Xtro\slc6a17, Xtro\slc6a7, Xtro\slc6a3, Xtro\slc6a15, Xtro\slc6a5" "Mmus\Slc6a11, Mmus\Slc6a17, Mmus\Slc6a20b, Mmus\Slc6a19, Mmus\Slc6a14, Mmus\Slc6a2, Mmus\Slc6a18, Mmus\Slc6a20a, Mmus\Slc6a3, Mmus\Slc6a6, Mmus\Slc6a12, Mmus\Slc6a8, Mmus\Slc6a21, Mmus\Slc6a5, Mmus\Slc6a9, Mmus\Slc6a4, Mmus\Slc6a1, Mmus\Slc6a13, Mmus\Slc6a16, Mmus\Slc6a7, Mmus\Slc6a15" "Hsap\SLC6A3, Hsap\SLC6A2, Hsap\SLC6A14, Hsap\SLC6A9, Hsap\SLC6A18, Hsap\SLC6A11, Hsap\SLC6A19, Hsap\SLC6A20, Hsap\SLC6A7, Hsap\SLC6A6, Hsap\SLC6A16, Hsap\SLC6A4, Hsap\SLC6A17, Hsap\SLC6A8, Hsap\SLC6A1, Hsap\SLC6A12, Hsap\SLC6A5, Hsap\SLC6A13, Hsap\SLC6A15" "viable,planar polarity defective" FBgn0015465 l(2)37Dm lethal (2) 37Dm http://flybase.org/reports/FBgn0015465 - gene - - - "l(2)E12, l(2)37Dm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005064 fs(2)OW204 female sterile (2) OW204 http://flybase.org/reports/FBgn0005064 - gene - - - fs(2)OW204 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030622 CG9101 - http://flybase.org/reports/FBgn0030622 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9101 IPR009069:Cysteine alpha-hairpin motif superfamily CG9101 11-Aug-17 DroID_v2017_08 "Drer\chchd7, Drer\chchd6b, Drer\chchd3b, Drer\chchd3a" Scer\COX23 Cele\chch-3 "Xtro\chchd6, Xtro\chchd3" "Mmus\Chchd7, Mmus\Chchd3, Mmus\Chchd6" "Hsap\CHCHD6, Hsap\CHCHD3, Hsap\CHCHD7" FBgn0031440 CG15395 - http://flybase.org/reports/FBgn0031440 protein_coding_gene - - - CG15395 - CG15395 11-Aug-17 DroID_v2017_08 Drer\tpx2 - Cele\ZK1053.3 - Mmus\Tpx2 Hsap\TPX2 viable FBgn0264573 CR43945 - http://flybase.org/reports/FBgn0264573 non_protein_coding_gene - - - "CR43945, lincRNA.637" - CR43945 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033376 CG8777 - http://flybase.org/reports/FBgn0033376 protein_coding_gene - nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from mutant phenotype - "CG8777, SKI3, ski3, dSki3" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG8777 11-Aug-17 DroID_v2017_08 Drer\ttc37 "Scer\TOM70, Scer\TOM71, Scer\SKI3" Cele\Y47A7.1 Xtro\ttc37 Mmus\Ttc37 Hsap\TTC37 FBgn0001597 l(1)CP7 lethal (1) CP7 http://flybase.org/reports/FBgn0001597 - gene - - - l(1)CP7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0017362 l(3)89Bt lethal (3) 89Bt http://flybase.org/reports/FBgn0017362 - gene - - - "l(3)89Br, l(3)89Bt" - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0038339 CG6118 - http://flybase.org/reports/FBgn0038339 protein_coding_gene - regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 CG6118 "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG6118 11-Aug-17 DroID_v2017_08 - - Cele\ztf-25 - Mmus\Zbtb39 Hsap\ZBTB39 lethal FBgn0260625 d00627 - http://flybase.org/reports/FBgn0260625 gene - - - d00627 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0034299 CG5757 - http://flybase.org/reports/FBgn0034299 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR018094, InterPro:IPR018095 uridylate kinase activity ; GO:0009041 | inferred from biological aspect of ancestor with PANTHER:PTN000038985 thymidylate kinase activity ; GO:0004798 | inferred from sequence or structural similarity with SGD:S000003818 thymidylate kinase activity ; GO:0004798 | inferred from biological aspect of ancestor with PANTHER:PTN000038985 uridylate kinase activity ; GO:0009041 | inferred from sequence or structural similarity with SGD:S000003818" dUDP biosynthetic process ; GO:0006227 | inferred from sequence or structural similarity with SGD:S000003818 dTDP biosynthetic process ; GO:0006233 | inferred from biological aspect of ancestor with PANTHER:PTN000038985 dTTP biosynthetic process ; GO:0006235 | inferred from sequence or structural similarity with SGD:S000003818 dTTP biosynthetic process ; GO:0006235 | inferred from biological aspect of ancestor with PANTHER:PTN000038985 dUDP biosynthetic process ; GO:0006227 | inferred from biological aspect of ancestor with PANTHER:PTN000038985 dTDP biosynthetic process ; GO:0006233 | inferred from sequence or structural similarity with SGD:S000003818 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000038985 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000003818 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003818 CG5757 "IPR018094:Thymidylate kinase, IPR018095:Thymidylate kinase, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5757 11-Aug-17 DroID_v2017_08 "Drer\dtymk, Drer\cmpk2" Scer\CDC8 Cele\dtmk-1 "Xtro\cmpk2, Xtro\dtymk" "Mmus\Cmpk2, Mmus\Dtymk" "Hsap\CMPK2, Hsap\DTYMK" "viable,fertile" FBgn0262411 mir-92a mir-92a stem loop http://flybase.org/reports/FBgn0262411 miRNA_gene - "head involution ; GO:0008258 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from direct assay positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from genetic interaction with Ge-1, me31B" - "miR-92a, mir-92a, MIR-92, CR42955, CR33571, dme-mir-92a, miR-92A, mIR-92a, miR-92, mir-92, dme-miR-92a" - CR42955 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage "visible,lethal" "wing,wing hair,wing sensillum,ectopic" FBgn0025122 su(RpII140[Z36])S6 su(RpII140[Z36])S6 http://flybase.org/reports/FBgn0025122 - gene - - - "Z36[S6], su(RpII140[Z36])S6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016997 limbo limbo http://flybase.org/reports/FBgn0016997 - gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "lio, limbo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile,male fertile" "lamina anlage,medulla anlage,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon" FBgn0264890 CR44081 - http://flybase.org/reports/FBgn0264890 non_protein_coding_gene - - - CR44081 - CR44081 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065258 l(2)SH2098 lethal (2) SH2098 http://flybase.org/reports/FBgn0065258 gene - - - "l(2)SH2098, l(2)SH2 2098" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037624 CG8223 - http://flybase.org/reports/FBgn0037624 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - nucleus ; GO:0005634 | inferred from direct assay CG8223 "IPR011990:Tetratricopeptide-like helical domain, IPR019734:Tetratricopeptide repeat" CG8223 11-Aug-17 DroID_v2017_08 Drer\nasp - "Cele\nasp-2, Cele\nasp-1" Xtro\nasp Mmus\Nasp Hsap\NASP "viable,visible" trichogen cell FBgn0053198 pen-2 presenilin enhancer http://flybase.org/reports/FBgn0053198 protein_coding_gene - Notch receptor processing ; GO:0007220 | inferred from biological aspect of ancestor with PANTHER:PTN000418973 "late endosome ; GO:0005770 | inferred from direct assay gamma-secretase complex ; GO:0070765 | inferred from physical interaction with aph-1, nct, Psn recycling endosome ; GO:0055037 | inferred from direct assay" "Pen-2, CG33198, anon-AE003800.1, pen-2, dPen-2" "IPR019379:Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunit" CG33198 11-Aug-17 DroID_v2017_08 Drer\psenen - Cele\pen-2 Xtro\psenen Mmus\Psenen "Hsap\PSENEN, Hsap\LIN37" viable FBgn0026374 Rhp Rhophilin http://flybase.org/reports/FBgn0026374 - protein_coding_gene - signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR011072 - "CG8497, Rhp" "IPR001478:PDZ domain, IPR004328:BRO1 domain, IPR011072:HR1 rho-binding repeat" CG8497 11-Aug-17 DroID_v2017_08 "Drer\brox, Drer\rhpn1, Drer\pdcd6ip, Drer\ptpn23b, Drer\rhpn2, Drer\ptpn23a" "Scer\BRO1, Scer\RIM20" "Cele\B0507.2, Cele\ego-2" "Xtro\rhpn1, Xtro\rhpn2, Xtro\ptpn23, Xtro\brox, Xtro\pdcd6ip" "Mmus\Rhpn1, Mmus\Ptpn23, Mmus\Pdcd6ip, Mmus\Brox, Mmus\Rhpn2" "Hsap\PDCD6IP, Hsap\BROX, Hsap\RHPN2, Hsap\RHPN1, Hsap\PTPN23" "lethal,recessive,viable" FBgn0011594 fs(3)6284 fs(3)6284 http://flybase.org/reports/FBgn0011594 - gene - - - fs(3)6284 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile ovary FBgn0004171 Mst98Cb Male-specific RNA 98Cb http://flybase.org/reports/FBgn0004171 "FBgn0039575, FBgn0044584" protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatid development ; GO:0007286 | inferred from expression pattern sperm flagellum ; GO:0036126 | inferred from direct assay "MST98Cb, Mst, Mst98C, mst(3)gl-13, CG18396, anon-WO0140519.46, Mst98Cb" - CG18396 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22495 K -0.469181941 -0.297419183 -0.158950211 0.263174333 -1.801402851 -1.037328446 FBgn0034446 Arl6 ADP ribosylation factor-like 6 http://flybase.org/reports/FBgn0034446 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006689, InterPro:IPR024156 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with WB:WBGene00000193" small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 intracellular transport ; GO:0046907 | inferred from sequence or structural similarity with WB:WBGene00000193 cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern axoneme ; GO:0005930 | inferred from sequence or structural similarity with WB:WBGene00000193 cilium ; GO:0005929 | inferred by curator from GO:0060271 "CG7735, A1ZBK9, Arl6, BBS3, ARL6" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024156:Small GTPase superfamily, ARF type" CG7735 11-Aug-17 DroID_v2017_08 "Drer\arf2a, Drer\arf3a, Drer\arl6, Drer\arl5a, Drer\arf5, Drer\arl14, Drer\arl4ab, Drer\arl9, Drer\arl8, Drer\si:ch1073-165f9.2, Drer\arl4d, Drer\arf1, Drer\arl4cb, Drer\arf3b, Drer\arl4ca, Drer\arf4a, Drer\arl5c, Drer\arl4aa, Drer\zgc:110286, Drer\trim23, Drer\arl11, Drer\zgc:77650" "Scer\ARF2, Scer\ARF3, Scer\ARF1" Cele\arl-6 "Xtro\arl14, Xtro\arf3, Xtro\arl11, Xtro\arl11, Xtro\arf5, Xtro\arf4, Xtro\arl4c, Xtro\arl9, Xtro\arl5b, Xtro\arl5a, Xtro\arl4a, Xtro\arl6, Xtro\arf1, Xtro\trim23, Xtro\arl5c" "Mmus\Arl4c, Mmus\Arf4, Mmus\Arl5b, Mmus\Arl5a, Mmus\Arf1, Mmus\Arl11, Mmus\Arl4d, Mmus\Arf5, Mmus\Arl6, Mmus\Arl5c, Mmus\Trim23, Mmus\Arl9, Mmus\Arl4a, Mmus\Arf3, Mmus\Arf2" "Hsap\ARL5C, Hsap\ARL5A, Hsap\TRIM23, Hsap\ARF1, Hsap\ARL9, Hsap\ARF5, Hsap\ARL14, Hsap\ARL4C, Hsap\ARL17B, Hsap\ARL4D, Hsap\ARL4A, Hsap\ARL6, Hsap\ARL11, Hsap\ARL5B, Hsap\ARF3, Hsap\ARF4" "viable,fertile" FBgn0026402 NiPp1 Nuclear inhibitor of Protein phosphatase 1 http://flybase.org/reports/FBgn0026402 FBgn0034178 protein_coding_gene mRNA binding ; GO:0003729 | inferred from direct assay protein serine/threonine phosphatase inhibitor activity ; GO:0004865 | inferred from direct assay protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B protein phosphatase inhibitor activity ; GO:0004864 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype negative regulation of protein dephosphorylation ; GO:0035308 | inferred from mutant phenotype nuclear speck ; GO:0016607 | inferred from direct assay "NIPP1Dm, NIPP-1Dm, NiPp-1, CG8980, NiPp1, NIPP1, nipp1" "IPR000253:Forkhead-associated (FHA) domain, IPR008984:SMAD/FHA domain" CG8980 11-Aug-17 DroID_v2017_08 "Drer\ppp1r8a, Drer\ppp1r8b" - Cele\B0511.7 Xtro\ppp1r8 Mmus\Ppp1r8 Hsap\PPP1R8 "visible,lethal,mitotic cell cycle defective,locomotor rhythm defective,viable" "wing,photoreceptor cell R1 & axonGMR.PF,photoreceptor cell R2 & axonGMR.PF,photoreceptor cell R3 & axonGMR.PF,photoreceptor cell R4 & axonGMR.PF,photoreceptor cell R5 & axonGMR.PF,embryonic/larval optic neuropil,mitosis & nuclear chromosomearm.PS,indirect flight muscle,trichogen cell" FBgn0085371 CG34342 - http://flybase.org/reports/FBgn0085371 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34342, CG10629, CG32422" "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG34342 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" - Cele\fard-1 Xtro\far1 "Mmus\Far1, Mmus\Far2" "Hsap\FAR2, Hsap\FAR1" FBgn0083956 CG34120 - http://flybase.org/reports/FBgn0083956 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 "CG1819, BcDNA:AT04622, CG32516, CG34120" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026082:ABC transporter A, ABCA" CG34120 11-Aug-17 DroID_v2017_08 "Drer\abca3b, Drer\abca1a, Drer\abch1, Drer\abca5, Drer\abca1b, Drer\abca12, Drer\abca2" - "Cele\abt-5, Cele\ced-7, Cele\abt-2, Cele\abt-4" "Xtro\abca4, Xtro\abca3, Xtro\abca9, Xtro\abca1, Xtro\abca8, Xtro\abca10, Xtro\abca2" "Mmus\Abca8b, Mmus\Abca1, Mmus\Abca14, Mmus\Abca7, Mmus\Abca4, Mmus\Abca12, Mmus\Abca2, Mmus\Abca5, Mmus\Abca8a, Mmus\Abca15, Mmus\Abca9, Mmus\Abca6, Mmus\Abca16, Mmus\Abca13, Mmus\Abca17, Mmus\Abca3" "Hsap\ABCA9, Hsap\ABCA4, Hsap\ABCA1, Hsap\ABCA12, Hsap\ABCA13, Hsap\ABCA7, Hsap\ABCA10, Hsap\ABCA6, Hsap\ABCA2, Hsap\ABCA5, Hsap\ABCA8, Hsap\ABCA3" viable FBgn0266128 82Y - http://flybase.org/reports/FBgn0266128 gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - 82Y - - 11-Aug-17 DroID_v2017_08 - - - - - - gravitaxis defective FBgn0011821 Pbp135 Phenylalkylamine-binding protein 135kD http://flybase.org/reports/FBgn0011821 - gene phenylalkylamine binding ; GO:0008145 | inferred from direct assay - - Pbp135 - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult head

FBgn0050025 CG30025 - http://flybase.org/reports/FBgn0050025 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 CG30025 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG30025 11-Aug-17 DroID_v2017_08 "Drer\zgc:153968, Drer\zgc:92590, Drer\tmprss4b, Drer\ctrl, Drer\prss60.1, Drer\LOC562139, Drer\zgc:163079, Drer\prss60.3, Drer\si:dkeyp-93a5.2, Drer\si:ch211-165b19.9, Drer\try, Drer\zgc:123295, Drer\zgc:55888, Drer\prss60.2, Drer\zgc:112160, Drer\zgc:112038" - "Cele\rab-11.1, Cele\try-1" - "Mmus\Prss55, Mmus\Prss34, Mmus\Gm10334, Mmus\Prss2, Mmus\Prss1, Mmus\Gm5771, Mmus\Try4, Mmus\Prss3, Mmus\Prss53, Mmus\2210010C04Rik, Mmus\Prss36, Mmus\Try10" "Hsap\PRSS27, Hsap\PRSS1, Hsap\PRSS53, Hsap\PRSS36, Hsap\PRSS45, Hsap\PRSS38, Hsap\PRSS22, Hsap\TPSG1, Hsap\PRSS33, Hsap\CMA1, Hsap\PRSS3, Hsap\PRSS8" FBgn0267849 Syx7 Syntaxin 7 http://flybase.org/reports/FBgn0267849 protein_coding_gene SNARE binding ; GO:0000149 | inferred from sequence or structural similarity with RGD:619747 protein binding ; GO:0005515 | inferred from physical interaction with Vps33B SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNAP receptor activity ; GO:0005484 | non-traceable author statement SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 protein binding ; GO:0005515 | inferred from physical interaction with Vps45 "multicellular organism growth ; GO:0035264 | inferred from mutant phenotype endosomal vesicle fusion ; GO:0034058 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | non-traceable author statement trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity plasma membrane to endosome transport ; GO:0048227 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype vesicle docking ; GO:0048278 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 neurotransmitter secretion ; GO:0007269 | non-traceable author statement establishment or maintenance of apical/basal cell polarity ; GO:0035088 | inferred from mutant phenotype positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype vesicle fusion ; GO:0006906 | inferred from sequence or structural similarity with RGD:619747" early endosome ; GO:0005769 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 plasma membrane ; GO:0005886 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with RGD:619747 early endosome ; GO:0005769 | "Syx7, avl, braided, Avl, dSyn7, CG5081, Syx, DmSyx7, Dm Syx7, SYX7, syx7, Aval, syx7/avl, FCP-C" "IPR010989:SNARE, IPR006011:Syntaxin, N-terminal domain, IPR000727:Target SNARE coiled-coil homology domain" CG5081 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-208k15.1, Drer\stx16, Drer\stx12, Drer\stx12l, Drer\stx17, Drer\stx7l" "Scer\VAM3, Scer\TLG2, Scer\PEP12" "Cele\syx-4, Cele\syx-3, Cele\syx-7, Cele\syx-17, Cele\syx-16" "Xtro\stx16, Xtro\tsnare1, Xtro\stx12, Xtro\stx7" "Mmus\Stx17, Mmus\Stx16, Mmus\Stx7, Mmus\Stx12" "Hsap\STX7, Hsap\STX16, Hsap\STX17, Hsap\TSNARE1, Hsap\STX12" FBgn0020562 anon-VII-C7 anon-VII-C7 http://flybase.org/reports/FBgn0020562 - gene - - - anon-VII-C7 - - 11-Aug-17 DroID_v2017_08 - - - - - - Bolwig nerve FBgn0060515 l(3)S103807b lethal (3) S103807b http://flybase.org/reports/FBgn0060515 gene - - - "1038/07, l(3)S103807b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085298 CG34269 - http://flybase.org/reports/FBgn0085298 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34269 IPR009071:High mobility group box domain CG34269 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265863 CR44652 - http://flybase.org/reports/FBgn0265863 non_protein_coding_gene - - - "lincRNA.366, CR44652" - CR44652 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029966 Ir7c Ionotropic receptor 7c http://flybase.org/reports/FBgn0029966 protein_coding_gene "ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR019594 extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model" detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR019594 integral component of membrane ; GO:0016021 | inferred from sequence model" "Ir7c, CT35324, CG15324, DmelIR7c, IR7c" "IPR001320:Ionotropic glutamate receptor, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG15324 11-Aug-17 DroID_v2017_08 "Drer\grid1a, Drer\LOC100537813, Drer\grid1b" - Cele\glr-8 - "Mmus\Grid1, Mmus\Grik4" Hsap\GRID1 viable FBgn0082584 spy spermeye http://flybase.org/reports/FBgn0082584 gene - - - spy - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065851 l(2)SH0306 lethal (2) SH0306 http://flybase.org/reports/FBgn0065851 gene - - - "l(2)SH0306, l(2)SH2 0306" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035504 Teh4 tipE homolog 4 http://flybase.org/reports/FBgn0035504 protein_coding_gene sodium channel regulator activity ; GO:0017080 | inferred from sequence or structural similarity with tipE regulation of sodium ion transport ; GO:0002028 | inferred from sequence or structural similarity with tipE integral component of membrane ; GO:0016021 | inferred from sequence model "CG15003, TEH4, anon-WO0172774.111, Teh4" IPR031578:Na+ channel auxiliary subunit TipE CG15003 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038234 mRpL11 mitochondrial ribosomal protein L11 http://flybase.org/reports/FBgn0038234 protein_coding_gene rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000184007 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049638 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049638 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000184007 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9Y3B7 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049638 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CG3351, L11, BcDNA:RE67638, mRpL11, rpl-11" "IPR000911:Ribosomal protein L11/L12, IPR020783:Ribosomal protein L11, C-terminal, IPR020784:Ribosomal protein L11, N-terminal" CG3351 11-Aug-17 DroID_v2017_08 Drer\mrpl11 Scer\MRPL19 Cele\mrpl-11 Xtro\mrpl11 Mmus\Mrpl11 Hsap\MRPL11 "viable,visible,lethal,recessive" trichogen cell FBgn0031372 CG7295 - http://flybase.org/reports/FBgn0031372 protein_coding_gene - - - CG7295 IPR001199:Cytochrome b5-like heme/steroid binding domain CG7295 11-Aug-17 DroID_v2017_08 - - "Cele\vem-1, Cele\tag-131" - - - viable DRSC00699 I -1.302535052 2.02421705 0.305493597 0.451989103 0.314887206 0.913530876 FBgn0017564 Nuc3 Nuclease 3 http://flybase.org/reports/FBgn0017564 - gene nuclease activity ; GO:0004518 | inferred from direct assay - mitochondrion ; GO:0005739 | inferred from direct assay Nuc3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069410 JJF175 JJF175 http://flybase.org/reports/FBgn0069410 gene - - - JJF175 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0040724 CG16906 - http://flybase.org/reports/FBgn0040724 protein_coding_gene - - - CG16906 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003734 torp torpid http://flybase.org/reports/FBgn0003734 - gene - - - torp - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,heat sensitive,neurophysiology defective" FBgn0050087 CG30087 - http://flybase.org/reports/FBgn0050087 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "CG8215, SP41, CR30087, CG30087" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG30087 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.7, Drer\si:dkey-21e2.12, Drer\si:dkey-21e2.15, Drer\si:ch211-165b19.9, Drer\si:ch211-165b19.5, Drer\gzm3" - "Cele\try-1, Cele\svh-1, Cele\try-3" - "Mmus\Cma2, Mmus\Mcpt1, Mmus\Gzme, Mmus\Gzmf, Mmus\Cma1, Mmus\Gzmg, Mmus\Mcpt9, Mmus\Gzmd, Mmus\Klk6, Mmus\Mcpt8, Mmus\Gzmc, Mmus\Mcpt4, Mmus\Gzmb, Mmus\Ctsg" "Hsap\CTSG, Hsap\CMA1, Hsap\GZMH, Hsap\GZMB" viable FBgn0260466 Indy-2 I'm not dead yet 2 http://flybase.org/reports/FBgn0260466 protein_coding_gene succinate transmembrane transporter activity ; GO:0015141 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 succinate transmembrane transporter activity ; GO:0015141 | inferred from sequence or structural similarity with UniProtKB:Q9VVT2 pyruvate transmembrane transporter activity ; GO:0050833 | inferred from sequence or structural similarity with UniProtKB:Q9VVT2 citrate transmembrane transporter activity ; GO:0015137 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 citrate transmembrane transporter activity ; GO:0015137 | inferred from sequence or structural similarity with UniProtKB:Q9VVT2 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR001898 pyruvate transport ; GO:0006848 | inferred from sequence or structural similarity with UniProtKB:Q9VVT2 determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:Q9VVT2 succinate transport ; GO:0015744 | inferred from sequence or structural similarity with UniProtKB:Q9VVT2 citrate transport ; GO:0015746 | inferred from sequence or structural similarity with UniProtKB:Q9VVT2 succinate transmembrane transport ; GO:0071422 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000815082 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with UniProtKB:Q9VVT2 "CG4961, CG32921, CG33933, anon-WO0140519.217, Indy-2" "IPR001898:Solute carrier family 13, IPR031312:Sodium/sulphate symporter, conserved site" CG33933 11-Aug-17 DroID_v2017_08 "Drer\slc13a3, Drer\slc13a5a, Drer\slc13a2, Drer\slc13a1, Drer\slc13a5b, Drer\slc13a4" "Scer\PHO91, Scer\PHO90, Scer\PHO87" "Cele\nac-2, Cele\nac-3, Cele\nac-1, Cele\B0285.6" "Xtro\slc13a1, Xtro\slc13a5, Xtro\slc13a2, Xtro\slc13a3, Xtro\slc13a4" "Mmus\Slc13a2, Mmus\Slc13a1, Mmus\Slc13a5, Mmus\Slc13a4, Mmus\Slc13a3" "Hsap\SLC13A3, Hsap\SLC13A5, Hsap\SLC13A1, Hsap\SLC13A4, Hsap\SLC13A2" FBgn0069414 JJF164 JJF164 http://flybase.org/reports/FBgn0069414 gene - - - JJF164 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0035786 Tsp66A Tetraspanin 66A http://flybase.org/reports/FBgn0035786 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008952, InterPro:IPR018499 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model" "CG16991, CG1699, Dm.Tsp66A, Tsp66A" "IPR008952:Tetraspanin, EC2 domain, IPR018499:Tetraspanin/Peripherin" CG16991 11-Aug-17 DroID_v2017_08 - - - - - Hsap\CD63 FBgn0035148 CG3402 - http://flybase.org/reports/FBgn0035148 protein_coding_gene - regulation of Wnt signaling pathway ; GO:0030111 | inferred from electronic annotation with InterPro:IPR017268 Rho protein signal transduction ; GO:0007266 | inferred from electronic annotation with InterPro:IPR017268 - "BcDNA:LD06317, CG3402" "IPR001478:PDZ domain, IPR017268:Tax1-binding protein 3" CG3402 11-Aug-17 DroID_v2017_08 "Drer\tax1bp3, Drer\synj2bp" - Cele\C45G9.7 Xtro\tax1bp3 "Mmus\Sdcbp, Mmus\Tax1bp3, Mmus\Slc9a3r2, Mmus\Synj2bp-cox16, Mmus\Sdcbp2" "Hsap\TAX1BP3, Hsap\SLC9A3R2, Hsap\SLC9A3R1, Hsap\SDCBP, Hsap\SYNJ2BP" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0085460 CG34431 - http://flybase.org/reports/FBgn0085460 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34431, CG14766" - CG34431 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263941 BG00121 - http://flybase.org/reports/FBgn0263941 gene - - - BG00121 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0028380 fal falten http://flybase.org/reports/FBgn0028380 protein_coding_gene - - cellular_component ; GO:0005575 | no biological data available "CG9670, fal, Q9VVY4_DROME" "IPR003607:HD/PDEase domain, IPR006674:HD domain" CG9670 11-Aug-17 DroID_v2017_08 "Drer\LOC793232, Drer\LOC572225, Drer\si:ch211-233g6.2, Drer\samhd1" - Cele\ZK177.8 Xtro\samhd1 Mmus\Samhd1 Hsap\SAMHD1 viable DRSC11087 E -1.003268317 -0.02813143 1.685470732 1.182592967 -1.064316741 -0.319328393 FBgn0267337 rn rotund http://flybase.org/reports/FBgn0267337 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred by curator from GO:0000977,GO:0005634" "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with WB:WBGene00003015 "rn, roe, Rn, CG42277, CG10040, 5.3, P5.3, Dipr, CG14603, CG14600, CG32466, CG14601, CG32467, tot, tod" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG42277 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-155e24.3, Drer\LOC103909987, Drer\im:7141269, Drer\si:ch211-241b2.4, Drer\LOC560148, Drer\drl, Drer\zgc:165514, Drer\si:ch73-40a17.4, Drer\wu:fe17e08, Drer\znf384l, Drer\LOC108179164, Drer\si:ch211-198a12.6, Drer\znf362a, Drer\si:ch211-154o6.2, Drer\si:dkey-261j4.4, Drer\zbtb24, Drer\LOC101883594, Drer\LOC799968, Drer\si:dkey-262g12.3, Drer\LOC101883230, Drer\si:ch73-299h12.9, Drer\LOC100537317, Drer\LOC103911016, Drer\si:dkey-261j4.5, Drer\si:dkey-34m19.3, Drer\znf362b, Drer\si:ch211-276c2.4, Drer\LOC100333031, Drer\LOC100330167, Drer\zgc:112998, Drer\LOC100538142, Drer\si:dkey-261j4.3, Drer\si:ch211-222k6.2, Drer\zgc:171673" Scer\AZF1 "Cele\sdz-12, Cele\C46E10.9, Cele\scrt-1, Cele\Y48G8AL.10, Cele\klf-1, Cele\che-1, Cele\Y56A3A.28, Cele\Y55F3AM.14, Cele\lin-29" "Xtro\znf384, Xtro\znf367" "Mmus\Zfp853, Mmus\Maz, Mmus\Zfp367, Mmus\Zfp362, Mmus\Zbtb24, Mmus\Zfp384, Mmus\Zfp637, Mmus\Vezf1" "Hsap\ZNF384, Hsap\ZNF362, Hsap\ZNF367, Hsap\ZNF32, Hsap\MAZ, Hsap\ZNF853, Hsap\VEZF1, Hsap\ZNF850" " spermatogenesis && adult stage , prepupal stage | 0-2 hr , pupal stage | early , pupal stage && spermatogenesis && adult stage , embryonic stage--pupal stage , larval stage && pupal stage " " testis

, dorsal metathoracic disc

, imaginal disc

, adepithelial cell &&of dorsal mesothoracic disc

, ventral thoracic disc

, genital disc

, labial disc

, antennal disc

, spermatocyte

, dorsal mesothoracic disc

" """DRSC12543, DRSC22291"" " EK FBgn0027623 297\env 297 element env http://flybase.org/reports/FBgn0027623 - transposable_element_gene - - - "297\env, env" "IPR012014:Retroelement-encoded protein, env-related" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014373 poil-rare poil-rare http://flybase.org/reports/FBgn0014373 - gene - - - poil-rare - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263246 CG43389 - http://flybase.org/reports/FBgn0263246 protein_coding_gene - - - CG43389 - CG43389 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005659 Ets98B Ets at 98B http://flybase.org/reports/FBgn0005659 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418, InterPro:IPR003118 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000218930" cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 "D-ets4, D-ets-4, Ets, ETS4, D-Ets-4, ets98B, Ets4, CG5583, Ets98B" "IPR000418:Ets domain, IPR003118:Pointed domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR013761:Sterile alpha motif/pointed domain" CG5583 11-Aug-17 DroID_v2017_08 "Drer\spic, Drer\si:dkey-257i7.5, Drer\spi1a, Drer\spdef, Drer\spi1b" - Cele\ets-4 "Xtro\spib, Xtro\spdef, Xtro\spi1" "Mmus\Spic, Mmus\Spi1, Mmus\Spdef, Mmus\Spib" "Hsap\SPIC, Hsap\SPDEF, Hsap\SPIB, Hsap\SPI1" embryonic stage "

ubiquitous , pole cell

" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0086602 snoRNA:Psi28S-3436b snoRNA:Psi28S-3436b http://flybase.org/reports/FBgn0086602 snoRNA_gene - - - "snoRNA:75, psi28S-3436b, Dm-75, snoR75, CR33799, Psi28S-3436b, snoRNA:Psi28S-3436b" - CR33799 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003951 uncl uncoordinated-like http://flybase.org/reports/FBgn0003951 - gene - adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype - "l(1)Q-456, R-10-10, l(1)R-10-10, l(1)R10-10, Q456, 25, 24, 17, l(1)20Ae, uncl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective,lethal,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,touch sensitivity defective,germline clone,maternal effect,lethal - all die before end of larval stage,some die during larval stage,touch perception defective,somatic clone" "wing,leg,macrochaeta,adult antennal nerve,egg chamber,germline clone,maternal effect" FBgn0003667 tiny-bristle tiny bristle http://flybase.org/reports/FBgn0003667 - gene - - - "tiny-bristle, tb" - - 11-Aug-17 DroID_v2017_08 - - - - - - female semi-sterile "macrochaeta,wing" FBgn0084775 EP2370 EP2370 http://flybase.org/reports/FBgn0084775 gene - - - EP2370 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032079 CG31886 - http://flybase.org/reports/FBgn0032079 protein_coding_gene - - - "CG31886, CG9524, anon-WO0172774.161, anon-WO0172774.159" "IPR032008:Domain of unknown function DUF4792, IPR032010:Domain of unknown function DUF4793" CG31886 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,viable" FBgn0005317 N-b Notch b http://flybase.org/reports/FBgn0005317 - gene - - - "N-2, N-b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" wing FBgn0037315 Cerk Ceramide kinase http://flybase.org/reports/FBgn0037315 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 ceramide kinase activity ; GO:0001729 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern ceramide metabolic process ; GO:0006672 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype pole cell migration ; GO:0007280 | inferred from genetic interaction with Mulk imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "dcerk, DCERK, CG16708, Cerk, Dcerk, CerK" "IPR001206:Diacylglycerol kinase, catalytic domain, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG16708 11-Aug-17 DroID_v2017_08 "Drer\zgc:158263, Drer\cerk, Drer\cerkl" "Scer\LCB5, Scer\LCB4" "Cele\F52C9.3, Cele\sphk-1, Cele\T10B11.2" "Xtro\cerkl, Xtro\cerk" "Mmus\Cerkl, Mmus\Cerk, Mmus\Sphk2, Mmus\Sphk1" "Hsap\CERK, Hsap\SPHK2, Hsap\CERKL, Hsap\SPHK1" "partially lethal - majority die,neurophysiology defective,viable,visible,some die during pupal stage" "rhabdomere,eye photoreceptor cell,trichogen cell,mesothoracic tergum" FBgn0260721 CR42548 - http://flybase.org/reports/FBgn0260721 pseudogene_attribute - - - CR42548 - CR42548 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027123 l(?)13R lethal (?) 13R http://flybase.org/reports/FBgn0027123 - gene - - - l(?)13R - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004428 LysE Lysozyme E http://flybase.org/reports/FBgn0004428 "FBgn0002575, FBgn0063103" protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 lysozyme activity ; GO:0003796 | inferred from sequence or structural similarity negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype - "LysE, lysE, CG1180, BcDNA:LP07339, Lys E" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CG1180 11-Aug-17 DroID_v2017_08 "Drer\lyz, Drer\LOC100334363, Drer\LOC100536671" - - Xtro\MGC89221 "Mmus\Lyz2, Mmus\Spaca7, Mmus\9530003J23Rik, Mmus\Lyzl6, Mmus\Spaca1, Mmus\Lyz1, Mmus\Lyzl1, Mmus\Spaca4, Mmus\Spaca3, Mmus\1700016D06Rik, Mmus\Lalba, Mmus\Lyzl4, Mmus\Spaca5" "Hsap\LYZL6, Hsap\LYZL4, Hsap\SPACA5, Hsap\LYZ, Hsap\SPACA1, Hsap\LYZL1, Hsap\SPACA3, Hsap\LYZL2, Hsap\SPACA4, Hsap\SPACA5B, Hsap\SPACA7, Hsap\LALBA" " larval stage&&adult stage , adult stage , larval stage " " adult midgut

, embryonic/larval midgut

" FBgn0039180 CG5715 - http://flybase.org/reports/FBgn0039180 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026 phagocytosis ; GO:0006909 | inferred from mutant phenotype" - CG5715 "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG5715 11-Aug-17 DroID_v2017_08 "Drer\tnfaip6, Drer\tll1, Drer\he1a, Drer\bmp1a, Drer\mep1b, Drer\neto1l, Drer\LOC100003133, Drer\mep1a.2, Drer\si:ch211-167j6.5, Drer\neto1, Drer\he2, Drer\LOC797085, Drer\cdcp2, Drer\c6ast4, Drer\si:ch73-40a17.3, Drer\si:cabz01033205.3, Drer\c6ast1, Drer\csmd1a, Drer\mep1a.1, Drer\npsn, Drer\neto2b, Drer\bmp1b, Drer\he1b, Drer\c6ast3" - "Cele\ZC116.3, Cele\nas-13, Cele\nas-14, Cele\nas-7, Cele\nas-15, Cele\nas-12, Cele\nas-33, Cele\nas-1, Cele\nas-9, Cele\nas-6, Cele\Y19D10A.6, Cele\nas-4, Cele\nas-8, Cele\nas-3, Cele\nas-2, Cele\nas-39" "Xtro\bmp1, Xtro\LOC100489456, Xtro\tnfaip6, Xtro\mep1b, Xtro\cubn, Xtro\accs, Xtro\mep1a, Xtro\uvs.2, Xtro\tll1, Xtro\tll2, Xtro\LOC100492324" "Mmus\Tnfaip6, Mmus\Astl, Mmus\Cdcp2, Mmus\Tll1, Mmus\Adgrg6, Mmus\Tll2, Mmus\Cubn, Mmus\Mep1b, Mmus\Mfrp, Mmus\Mep1a, Mmus\Neto2, Mmus\Neto1, Mmus\Bmp1" "Hsap\TLL2, Hsap\MFRP, Hsap\TLL1, Hsap\MEP1A, Hsap\BMP1, Hsap\NETO1, Hsap\CUBN, Hsap\CDCP2, Hsap\ASTL, Hsap\MEP1B, Hsap\TNFAIP6, Hsap\ADGRG6, Hsap\NETO2" viable FBgn0000049 l(1)adl1 lethal (1) adl1 http://flybase.org/reports/FBgn0000049 FBgn0005127 gene - - - "l(1)7Dn, adl-1, l(1)adl-1, l(1)J1649, addA, l(1)adl1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,heat sensitive,lethal" FBgn0086380 BG00386 - http://flybase.org/reports/FBgn0086380 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - BG00386 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective,behavior defective,recessive" FBgn0010029 E(Dl)F42 Enhancer of Delta F42 http://flybase.org/reports/FBgn0010029 - gene - - - E(Dl)F42 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069108 mus316 mutagen-sensitive 316 http://flybase.org/reports/FBgn0069108 gene - - - mus316 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0262442 mir-2501 mir-2501 stem loop http://flybase.org/reports/FBgn0262442 miRNA_gene - - - "mir-2501, CR43005" - CR43005 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010547 l(2)03605 lethal (2) 03605 http://flybase.net/reports/FBgn0010547.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0053107 CG33107 - http://flybase.org/reports/FBgn0053107 protein_coding_gene - - - "CG5275, CG33107" - CG33107 11-Aug-17 DroID_v2017_08 - Scer\DPH5 - Xtro\dph5 Mmus\Dph5 Hsap\DPH5 "viable,visible" trichogen cell DRSC21898 K -0.259922383 0.837030916 -0.238442443 0.456770809 2.008709802 -0.938442979 FBgn0052198 CG32198 - http://flybase.org/reports/FBgn0052198 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32198 - CG32198 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053310 CG33310 - http://flybase.org/reports/FBgn0053310 protein_coding_gene - sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR000402 potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR000402 sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred from electronic annotation with InterPro:IPR000402 "BG:DS00929.6, CG15274, CG33310" IPR000402:Sodium/potassium-transporting ATPase subunit beta CG33310 11-Aug-17 DroID_v2017_08 "Drer\atp1b2b, Drer\atp1b2a, Drer\atp1b1a, Drer\gabbr1a, Drer\atp1b4, Drer\atp1b1b, Drer\atp1b3a, Drer\gabbr2, Drer\atp1b3b, Drer\gpr156" - "Cele\nkb-2, Cele\nkb-3, Cele\nkb-1" "Xtro\atp1b1, Xtro\atp1b2, Xtro\gabbr2, Xtro\atp1b3, Xtro\atp4b, Xtro\gabbr1, Xtro\atp1b4" "Mmus\Atp1b3, Mmus\Atp1b2, Mmus\Atp1b4, Mmus\Gpr156, Mmus\Gabbr1, Mmus\Gabbr2, Mmus\Atp1b1, Mmus\Atp4b" "Hsap\ATP4B, Hsap\ATP1B3, Hsap\ATP1B1, Hsap\ATP1B2, Hsap\GPR156, Hsap\ATP1B4, Hsap\GABBR1, Hsap\GABBR2" viable FBgn0033860 S-Lap5 Sperm-Leucylaminopeptidase 5 http://flybase.org/reports/FBgn0033860 protein_coding_gene "metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283 mesoderm development ; GO:0007498 | inferred from expression pattern" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "CG18369, S-Lap5, S-LAP 5" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG18369 11-Aug-17 DroID_v2017_08 "Drer\lap3, Drer\zgc:152830, Drer\rfwd2, Drer\npepl1" - "Cele\lap-1, Cele\lap-2" "Xtro\lap3, Xtro\rfwd2" "Mmus\Lap3, Mmus\Npepl1, Mmus\Rfwd2" "Hsap\NPEPL1, Hsap\LAP3" FBgn0035039 Adck aarF domain containing kinase http://flybase.org/reports/FBgn0035039 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from sequence or structural similarity with SGD:S000004243 protein phosphorylation ; GO:0006468 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from sequence or structural similarity with SGD:S000004243 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with SGD:S000004243 "CG3608, cg3608, Adck" "IPR000719:Protein kinase domain, IPR004147:UbiB domain, IPR011009:Protein kinase-like domain" CG3608 11-Aug-17 DroID_v2017_08 "Drer\adck1, Drer\adck5" "Scer\YPL109C, Scer\MCP2" "Cele\Y32H12A.7, Cele\D2023.6" Xtro\adck1 "Mmus\Adck1, Mmus\Adck2, Mmus\Adck5" "Hsap\ADCK5, Hsap\ADCK2, Hsap\ADCK1" "viable,visible" trichogen cell FBgn0005185 l(2)S13 lethal of Seto 13 http://flybase.org/reports/FBgn0005185 - gene - - - l(2)S13 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262283 mir-985 mir-985 stem loop http://flybase.org/reports/FBgn0262283 miRNA_gene - - - "dme-mir-985, mir-985, CR42990, miR-985, lincRNA.1008" - CR42990 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010530 l(2)03105 lethal (2) 03105 http://flybase.org/reports/FBgn0010530 FBgn0021809 gene - - - "l(2)3105, l(2)k16702, l(2)03105" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267063 CR45507 - http://flybase.org/reports/FBgn0267063 non_protein_coding_gene - - - CR45507 - CR45507 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262578 CG43118 - http://flybase.org/reports/FBgn0262578 protein_coding_gene - - - CG43118 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267492 Mst77Y-7 Male-specific transcript 77Y 7 http://flybase.org/reports/FBgn0267492 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F "Mst77Y-7, CG45768, Mst77Y-7a, MST77Y" - CG45768 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051199 CG31199 - http://flybase.org/reports/FBgn0051199 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "CG17837, CG31199" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG31199 11-Aug-17 DroID_v2017_08 - - - - - Hsap\PAMR1 viable FBgn0000586 es ether-sensitive http://flybase.org/reports/FBgn0000586 - gene - - - es - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced,chemical sensitive,recessive" FBgn0005710 l(1)TK113 lethal (1) TK113 http://flybase.org/reports/FBgn0005710 - gene - - - "l113, l(1)TK113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" eye FBgn0016958 tilO touch insensitive larva O http://flybase.org/reports/FBgn0016958 - gene - - - "line 317, tilO" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective,visible,somatic clone" "macrochaeta,somatic clone,trichome" FBgn0067089 I16 I16 http://flybase.org/reports/FBgn0067089 gene - - - I16 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0027652 l(2)32BCa lethal (2) 32BCa http://flybase.org/reports/FBgn0027652 - gene - - - l(2)32BCa - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0004172 Mst84Da Male-specific RNA 84Da http://flybase.org/reports/FBgn0004172 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis ; GO:0007283 | inferred from genetic interaction with Mst84Db, Mst84Dc, Mst84Dd sperm axoneme assembly ; GO:0007288 | inferred from genetic interaction with Mst84Db, Mst84Dc, Mst84Dd" cellular_component ; GO:0005575 | no biological data available "Mst, Mstprox, Mst ORF, Mst84, Mst87D, mst(3)gl-1, CG17946, Mst84Da" IPR005634:Male specific sperm protein CG17946 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038953 CG18596 - http://flybase.org/reports/FBgn0038953 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001537 tRNA (guanine) methyltransferase activity ; GO:0016423 | inferred from biological aspect of ancestor with PANTHER:PTN000247165 rRNA (guanosine-2'-O-)-methyltransferase activity ; GO:0070039 | inferred from biological aspect of ancestor with PANTHER:PTN001738495 enzyme-directed rRNA 2'-O-methylation ; GO:0000453 | inferred from biological aspect of ancestor with PANTHER:PTN001738495 tRNA methylation ; GO:0030488 | inferred from biological aspect of ancestor with PANTHER:PTN000247165 - CG18596 "IPR001537:tRNA/rRNA methyltransferase, SpoU type, IPR011989:Armadillo-like helical, IPR029028:Alpha/beta knot methyltransferases, IPR029026:tRNA (guanine-N1-)-methyltransferase, N-terminal" CG18596 11-Aug-17 DroID_v2017_08 Drer\si:dkey-85a20.4 Scer\TRM3 Cele\T14B4.1 - Mmus\Tarbp1 Hsap\TARBP1 viable FBgn0011246 ms(2)42D male sterile (2) 42D http://flybase.org/reports/FBgn0011246 - gene - - - "ms(2)09967, ms(2)42D" - - 11-Aug-17 DroID_v2017_08 - - - - - - male semi-sterile FBgn0030630 CG12608 - http://flybase.org/reports/FBgn0030630 protein_coding_gene molecular_function ; GO:0003674 | no biological data available ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with MGI:MGI:1915333 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with MGI:MGI:1915333 CG12608 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG12608 11-Aug-17 DroID_v2017_08 "Drer\wdr55, Drer\pak1ip1" "Scer\JIP5, Scer\MAK11" Cele\Y44F5A.1 Xtro\pak1ip1 "Mmus\Wdr55, Mmus\Pak1ip1" "Hsap\PAK1IP1, Hsap\WDR55" FBgn0031800 CG9497 - http://flybase.org/reports/FBgn0031800 protein_coding_gene - - - CG9497 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG9497 11-Aug-17 DroID_v2017_08 - - "Cele\dhs-27, Cele\H06H21.8, Cele\C29F7.1, Cele\C29F7.2, Cele\nhr-246" - - - "viable,fertile" FBgn0083961 CG34125 - http://flybase.org/reports/FBgn0083961 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31652, CG34125" IPR022730:DAZ associated protein 2 CG34125 11-Aug-17 DroID_v2017_08 Drer\dazap2 - - - Mmus\Dazap2 Hsap\DAZAP2 FBgn0023183 Ocu Oculess http://flybase.org/reports/FBgn0023183 - gene - - - Ocu - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086030 snoRNA:Me18S-G393 - http://flybase.org/reports/FBgn0086030 snoRNA_gene - - - "snoRNA:Me18S-G393, Me18S-Gm393, CR34659" - CR34659 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016048 noose noose http://flybase.org/reports/FBgn0016048 - gene - - - noose - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" embryonic/larval brain FBgn0028054 l(3)S095109 lethal (3) S095109 http://flybase.org/reports/FBgn0028054 gene - - - "0951/09, l(3)S095109" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0066371 beluy beluy http://flybase.org/reports/FBgn0066371 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available beluy - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,memory defective" FBgn0015407 l(1)12Bb lethal (1) 12Bb http://flybase.org/reports/FBgn0015407 - gene - - - l(1)12Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,visible,male fertile,body color defective" "wing,adult abdomen,female" FBgn0036360 CG10713 - http://flybase.org/reports/FBgn0036360 protein_coding_gene - - - "CT28585, CG10713" IPR015943:WD40/YVTN repeat-like-containing domain CG10713 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002971 Nuc Nuclease http://flybase.org/reports/FBgn0002971 - gene - - - Nuc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005055 fs(2)OW101 female sterile (2) OW101 http://flybase.org/reports/FBgn0005055 - gene - - - fs(2)OW101 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265893 CR44682 - http://flybase.org/reports/FBgn0265893 non_protein_coding_gene - - - CR44682 - CR44682 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051064 CG31064 - http://flybase.org/reports/FBgn0051064 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab4 phagocytosis ; GO:0006909 | inferred from mutant phenotype - "CG6001, CG14261, CG31064, RUFY1" "IPR000306:FYVE zinc finger, IPR004012:RUN domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR017455:Zinc finger, FYVE-related, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31064 11-Aug-17 DroID_v2017_08 "Drer\zfyve28, Drer\rundc3ab, Drer\snx29, Drer\rubcn, Drer\pikfyve, Drer\rufy1, Drer\rufy3, Drer\rundc3aa, Drer\rufy2, Drer\rundc3b" "Scer\PIB2, Scer\FAB1" "Cele\B0416.4, Cele\lst-2, Cele\ppk-3" "Xtro\snx29, Xtro\zfyve28, Xtro\rufy2, Xtro\rundc3a, Xtro\rufy1, Xtro\rundc3b, Xtro\rufy3" "Mmus\Rufy2, Mmus\Pikfyve, Mmus\Rubcn, Mmus\Snx29, Mmus\Zfyve28, Mmus\Rundc3a, Mmus\Rufy1, Mmus\Rundc3b, Mmus\Rufy3" "Hsap\RUNDC3A, Hsap\RUFY2, Hsap\RUFY1, Hsap\RUFY3, Hsap\RUBCN, Hsap\ZFYVE28, Hsap\PIKFYVE, Hsap\SNX29, Hsap\RUNDC3B" viable FBgn0263974 qin qin http://flybase.org/reports/FBgn0263974 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:2685973 zinc ion binding ; GO:0008270 | inferred from sequence model" protein autoubiquitination ; GO:0051865 | inferred from sequence or structural similarity with MGI:MGI:2685973 posttranscriptional gene silencing by RNA ; GO:0035194 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay "qin, CG14303, CG14306, CG43726, kumo, Qin" "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR017907:Zinc finger, RING-type, conserved site, IPR000315:B-box-type zinc finger, IPR002999:Tudor domain" CG43726 11-Aug-17 DroID_v2017_08 "Drer\tdrd1, Drer\tdrd6, Drer\snd1, Drer\si:ch211-189e2.3, Drer\rnf17, Drer\si:dkeyp-93d12.1, Drer\tdrd7a" - - Xtro\snd1 "Mmus\Tdrd1, Mmus\Tdrd6, Mmus\Snd1, Mmus\Rnf17" "Hsap\TDRD5, Hsap\TDRD1, Hsap\TDRD15, Hsap\SND1, Hsap\RNF17, Hsap\TDRD7, Hsap\TDRD6" FBgn0044068 F72 F72 http://flybase.org/reports/FBgn0044068 gene - - - F72 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001015 fs(3)A6 female sterile (3) A6 http://flybase.org/reports/FBgn0001015 - gene - - - fs(3)A6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0051286 CG31286 - http://flybase.org/reports/FBgn0051286 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "NEST:bs36b12, BcDNA:AT25568, CG31286" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034113:Golgi-associated plant pathogenesis-related protein 1, SCP domain" CG31286 11-Aug-17 DroID_v2017_08 "Drer\crispld2, Drer\glipr2l, Drer\pi15a, Drer\pi15b, Drer\im:7150988, Drer\crispld1a, Drer\glipr1b, Drer\crispld1b, Drer\glipr2, Drer\r3hdml, Drer\LOC100536500, Drer\LOC101883528" "Scer\PRY1, Scer\PRY2, Scer\PRY3" "Cele\D2062.1, Cele\C07A4.3, Cele\scl-19, Cele\C07A4.2, Cele\vap-2" "Xtro\crisp2, Xtro\crispld2, Xtro\crisp1, Xtro\r3hdml, Xtro\crisp3, Xtro\MGC108118, Xtro\glipr2" "Mmus\Pi16, Mmus\Crispld1, Mmus\Glipr2, Mmus\R3hdml, Mmus\Crisp3, Mmus\Clec18a, Mmus\Glipr1l2, Mmus\Pi15, Mmus\Crisp4, Mmus\Crispld2, Mmus\Crisp2, Mmus\Glipr1, Mmus\Glipr1l1, Mmus\Crisp1" "Hsap\GLIPR1, Hsap\GLIPR2, Hsap\GLIPR1L1, Hsap\CRISP2, Hsap\CRISP1, Hsap\PI15, Hsap\CLEC18C, Hsap\PI16, Hsap\R3HDML, Hsap\GLIPR1L2, Hsap\CLEC18A, Hsap\CRISPLD1, Hsap\CRISPLD2, Hsap\CLEC18B" FBgn0028342 ATPsyndelta "ATP synthase, delta subunit" http://flybase.org/reports/FBgn0028342 protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000352454 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000002162" ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000002162 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000352454 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P30049 "mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from biological aspect of ancestor with PANTHER:PTN000352457 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P30049 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay" "CG2968, anon-WO03040301.110, anon-WO03040301.109, l(1)G0230, l (1) G0230, ATP5D, ATPD, ATPsyndelta" "IPR001469:ATP synthase, F1 complex, delta/epsilon subunit, IPR020547:ATP synthase delta/epsilon subunit, C-terminal domain, IPR020546:ATP synthase, F1 complex, delta/epsilon subunit, N-terminal" CG2968 11-Aug-17 DroID_v2017_08 Drer\atp5d Scer\ATP16 Cele\F58F12.1 Xtro\atp5d Mmus\Atp5d Hsap\ATP5D "viable,fertile,lethal,recessive" FBgn0266962 CG45413 - http://flybase.org/reports/FBgn0266962 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45413 - CG45413 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086402 BG02510 - http://flybase.org/reports/FBgn0086402 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02510 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0011966 tRNA:Arg-TCG-2-3 transfer RNA:Arginine-TCG 2-3 http://flybase.org/reports/FBgn0011966 "FBgn0003756, FBgn0011947, FBgn0051443, FBgn0060076" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002708.trna1-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002708-a, CR31443, tRNA:arg85Ca, chr3R.trna7-ArgTCG, tRNA-Arg-TCG-2-3, tRNA:Arg-TCG-2-3, tRNA:R:85Ca, CGA" - CR31443 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001394 l(1)2Da lethal (1) 2Da http://flybase.org/reports/FBgn0001394 - gene - - - "l(1)DF967, l(1)2Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0044478 EP643 EP643 http://flybase.org/reports/FBgn0044478 gene - - - "EP0643, EP643" - - 11-Aug-17 DroID_v2017_08 - - - - - - intersegmental nerve FBgn0005380 l(3)SG76 lethal (3) SG76 http://flybase.org/reports/FBgn0005380 - gene - - - l(3)SG76 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0038716 CG7342 - http://flybase.org/reports/FBgn0038716 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG7342 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG7342 11-Aug-17 DroID_v2017_08 "Drer\slc22a21, Drer\slc22a5" "Scer\HXT9, Scer\PHO84, Scer\GIT1, Scer\HXT2" "Cele\B0361.11, Cele\C53B4.1, Cele\T22F7.1, Cele\C46C2.2, Cele\Y66D12A.13, Cele\oct-1, Cele\ZK892.3, Cele\B0252.3, Cele\Y57G11C.23, Cele\Y51A2D.18, Cele\C06H5.6" - "Mmus\Slc22a5, Mmus\Slc22a21, Mmus\Slc22a27, Mmus\Slc22a4" "Hsap\SLC22A5, Hsap\SLC22A4" viable FBgn0085724 CG41622 - http://flybase.org/reports/FBgn0085724 protein_coding_gene - - - CG41622 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039752 CG15530 - http://flybase.org/reports/FBgn0039752 protein_coding_gene - - - CG15530 - CG15530 11-Aug-17 DroID_v2017_08 Drer\badb - - - Mmus\Bad Hsap\BAD viable FBgn0070052 2L-393-17 2L-393-17 http://flybase.org/reports/FBgn0070052 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 2L-393-17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "dorsal closure embryo,germline clone,maternal effect" FBgn0082360 HM160 HM160 http://flybase.org/reports/FBgn0082360 gene - - - HM160 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060618 l(3)S089013 lethal (3) S089013 http://flybase.org/reports/FBgn0060618 gene - - - "0890/13, l(3)S089013" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0060933 l(3)S041506 lethal (3) S041506 http://flybase.org/reports/FBgn0060933 gene - - - "0415/06, l(3)S041506" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002570 Mal-A1 Maltase A1 http://flybase.org/reports/FBgn0002570 - protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "CG8696, H, V, Mal-A1, mal_A1, LvpH, lvpH, Drome_A1" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG8696 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-202g17.3, Drer\slc3a2b, Drer\slc3a1, Drer\zgc:158423, Drer\slc3a2a" "Scer\IMA4, Scer\IMA1, Scer\MAL32, Scer\IMA3, Scer\MAL12, Scer\IMA2, Scer\IMA5" "Cele\atgp-1, Cele\atgp-2" "Xtro\slc3a2, Xtro\slc3a1" "Mmus\Slc3a1, Mmus\Slc3a2" "Hsap\SLC3A2, Hsap\SLC3A1" " larval stage | early third instar larval stage , larval stage | first instar , adult stage , larval stage | second instar " organism

viable FBgn0014305 l(3)neo53a lethal (3) neo53a http://flybase.org/reports/FBgn0014305 - gene - - - l(3)neo53a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011788 l(3)j1B8 lethal (3) j1B8 http://flybase.org/reports/FBgn0011788 - gene - - - l(3)j1B8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062686 EP1501 EP1501 http://flybase.org/reports/FBgn0062686 gene - - - "EP(X)1501, EP1501" - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0029750 CG3323 - http://flybase.org/reports/FBgn0029750 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3323 - CG3323 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085830 CR42197 - http://flybase.org/reports/FBgn0085830 non_protein_coding_gene - - - CR42197 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266926 CR45377 - http://flybase.org/reports/FBgn0266926 non_protein_coding_gene - - - CR45377 - CR45377 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002948 nod no distributive disjunction http://flybase.org/reports/FBgn0002948 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule motor activity ; GO:0003777 | inferred from mutant phenotype microtubule plus-end binding ; GO:0051010 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from biological aspect of ancestor with PANTHER:PTN001537455" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity distributive segregation ; GO:0032837 | inferred from mutant phenotype establishment of meiotic spindle orientation ; GO:0051296 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 positive regulation of microtubule polymerization ; GO:0031116 | inferred from direct assay meiotic chromosome segregation ; GO:0045132 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype spindle assembly involved in female meiosis I ; GO:0007057 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from direct assay "Nod, CG1763, DnMod, DmNod, l(1)TW6, nod, NOD, KIF 22, KIF22" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR010994:RuvA domain 2-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1763 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-375g18.1, Drer\kif21a, Drer\kif7, Drer\kif21b, Drer\LOC100149074, Drer\LOC100537698, Drer\kif4" Scer\KIP2 Cele\klp-19 "Xtro\kif21b, Xtro\kif7, Xtro\kif27, Xtro\kif21a, Xtro\kif4a" "Mmus\Kif4, Mmus\Kif21b, Mmus\Kif21a, Mmus\Kif7, Mmus\Kif27" "Hsap\KIF2C, Hsap\KIF21A, Hsap\KIF4B, Hsap\KIF27, Hsap\KIF21B, Hsap\KIF7, Hsap\KIF4A" " adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-3 , embryonic stage -- adult stage " " germarium

, ovariole

" "viable,meiotic cell cycle defective,female,fertile,recessive,lethal,male,cold sensitive,mitotic cell cycle defective,dominant" "meiosis & nuclear chromosome | female,meiosis & nuclear chromosome & oocyte,mitosis & nuclear chromosome,polytene chromosome chromocenter" FBgn0265748 CR44555 - http://flybase.org/reports/FBgn0265748 non_protein_coding_gene - - - "CR44555, lincRNA.542" - CR44555 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019887 anon-50Aa anon-50Aa http://flybase.org/reports/FBgn0019887 - gene - - - anon-50Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0265525 CR44375 - http://flybase.org/reports/FBgn0265525 non_protein_coding_gene - - - CR44375 - CR44375 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069085 sax::wit sax::wit http://flybase.org/reports/FBgn0069085 engineered_fusion_gene - - - sax::wit - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067770 frk franklin http://flybase.org/reports/FBgn0067770 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available frk - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "egg chamber,germline clone" FBgn0014136 cact::N cact::N http://flybase.org/reports/FBgn0014136 - engineered_fusion_gene - - - cact::N - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031138 CG11229 - http://flybase.org/reports/FBgn0031138 protein_coding_gene - - - CG11229 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0082341 HM54 HM54 http://flybase.org/reports/FBgn0082341 gene - - - HM54 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026063 KP78b KP78b http://flybase.org/reports/FBgn0026063 FBgn0022392 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:21680" microtubule cytoskeleton organization ; GO:0000226 | inferred from electronic annotation with InterPro:IPR033624 establishment of cell polarity ; GO:0030010 | inferred from electronic annotation with InterPro:IPR033624 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:21680 cellular_component ; GO:0005575 | no biological data available "CG17216, Kp78B, KP78B, KP78b, Kp78b" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR033624:Serine/threonine-protein kinase MARK/par1" CG17216 11-Aug-17 DroID_v2017_08 "Drer\sik2a, Drer\si:dkey-31m14.7, Drer\sik2b, Drer\mark2b, Drer\mark1, Drer\sik1, Drer\prkaa1, Drer\mark4a, Drer\mark2a, Drer\mark3b, Drer\mark3a" "Scer\KIN1, Scer\PRR1, Scer\KIN2, Scer\SNF1, Scer\FRK1" "Cele\kin-29, Cele\tag-257, Cele\par-1" "Xtro\mark4, Xtro\prkaa2, Xtro\prkaa1, Xtro\sik3, Xtro\mark2, Xtro\mark3, Xtro\sik2" "Mmus\Smok3b, Mmus\Gm5174, Mmus\Gm14147, Mmus\Gm6176, Mmus\Mark1, Mmus\Gm6902, Mmus\Gm7168, Mmus\Gm5157, Mmus\Gm5891, Mmus\Prkaa2, Mmus\1810024B03Rik, Mmus\Gm10662, Mmus\4921509C19Rik, Mmus\Gm4922, Mmus\Smok2b, Mmus\Gm10668, Mmus\Gm4565, Mmus\Sik3, Mmus\Sik1, Mmus\Smok2a, Mmus\Gm14151, Mmus\Mark3, Mmus\Gm4567, Mmus\Gm6882, Mmus\Mark2, Mmus\Prkaa1, Mmus\Mark4, Mmus\Nuak2, Mmus\Smok3a, Mmus\Gm6729, Mmus\Sik2" "Hsap\SIK3, Hsap\MARK1, Hsap\PRKAA1, Hsap\SIK1, Hsap\SIK2, Hsap\MARK4, Hsap\MARK3, Hsap\PRKAA2, Hsap\MARK2, Hsap\NUAK2" embryonic stage | extended germ band mesoderm | segmentally repeated

FBgn0266889 CR45350 - http://flybase.org/reports/FBgn0266889 non_protein_coding_gene - - - CR45350 - CR45350 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028187 l(3)S023825 lethal (3) S023825 http://flybase.org/reports/FBgn0028187 gene - - - "1165/12, 0826/09, 0816/07, 0743/09, 0690/07, 0685/02, 0621/12, 0428/24, 0300/04, 0291/20, 0238/26, 0238/16, 0610/02, 0238/25, 0238/20, l(3)S082609a, l(3)S116512, l(3)S081607, l(3)S074309a, l(3)S069007, l(3)S068502, l(3)S062112, l(3)S042824, l(3)S030004, l(3)S029120, l(3)S023816, l(3)S023826, l(3)S023825" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0031409 CG4271 - http://flybase.org/reports/FBgn0031409 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SPH164, CG4271" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG4271 11-Aug-17 DroID_v2017_08 "Drer\st14b, Drer\si:ch211-165b19.9" - - Xtro\tpsab1 Mmus\Egfbp2 Hsap\CFD viable FBgn0020271 moa moa http://flybase.org/reports/FBgn0020271 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)59ABd, sac, moa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,somatic clone,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage" "wing,somatic clone,larva" FBgn0019876 e(olfC) e(olfC) http://flybase.org/reports/FBgn0019876 - gene - - - "1a, anon-7Aa, e(olfC)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038225 soti scotti http://flybase.org/reports/FBgn0038225 protein_coding_gene - sperm individualization ; GO:0007291 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "soti, CG8489" IPR031397:Male-specific protein scotti CG8489 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile,male sterile,recessive,visible,body color defective" "individualization stage spermatid,chaeta,supernumerary,tormogen cell,mesothoracic tergum,waste bag,cystic bulge,nucleus & individualization stage spermatid" FBgn0259310 EP-Ib - http://flybase.org/reports/FBgn0259310 gene - - - EP-Ib - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin" FBgn0264790 CR44020 - http://flybase.org/reports/FBgn0264790 non_protein_coding_gene - - - CR44020 - CR44020 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011506 l(3)rK145 lethal (3) rK145 http://flybase.org/reports/FBgn0011506 - gene - - - l(3)rK145 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0065660 l(2)SH0714 lethal (2) SH0714 http://flybase.org/reports/FBgn0065660 gene - - - "l(2)SH0714, l(2)SH2 0714" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267186 CR45626 - http://flybase.org/reports/FBgn0267186 non_protein_coding_gene - - - CR45626 - CR45626 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030297 Gr10b Gustatory receptor 10b http://flybase.org/reports/FBgn0030297 protein_coding_gene - sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 "Gr10B2, CG12622, Gr10b, GR10b" IPR013604:7TM chemoreceptor CG12622 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0046323 ORY Occludin-Related Y http://flybase.org/reports/FBgn0046323 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "ory, ORY, CG40446, Ory" - CG40446 11-Aug-17 DroID_v2017_08 "Drer\ccdc146, Drer\cfap58" - - "Xtro\ccdc146, Xtro\cfap58" "Mmus\Cfap58, Mmus\Ccdc146, Mmus\Ccdc110" "Hsap\CCDC146, Hsap\CFAP58, Hsap\CCDC110" FBgn0034537 DMAP1 DNA methyltransferase 1 associated protein 1 http://flybase.org/reports/FBgn0034537 protein_coding_gene transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN000304415 "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from electronic annotation with InterPro:IPR008468 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR027109 chromatin remodeling ; GO:0006338 | inferred from electronic annotation with InterPro:IPR027109 histone H2A acetylation ; GO:0043968 | inferred from biological aspect of ancestor with PANTHER:PTN000304415 positive regulation of antimicrobial peptide production ; GO:0002225 | inferred from mutant phenotype histone H4 acetylation ; GO:0043967 | inferred from biological aspect of ancestor with PANTHER:PTN000304415 histone acetylation ; GO:0016573 | inferred from direct assay positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype" NuA4 histone acetyltransferase complex ; GO:0035267 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DMA, CG11132, dDMAP1, DMAP1, Q7K3D8_DROME" "IPR008468:DNA methyltransferase 1-associated 1, IPR027109:SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1, IPR032563:DAMP1, SANT/Myb-like domain" CG11132 11-Aug-17 DroID_v2017_08 Drer\dmap1 Scer\SWC4 Cele\ekl-4 Xtro\dmap1 Mmus\Dmap1 Hsap\DMAP1 "lethal,lethal - all die before end of pupal stage,some die during pupal stage" DRSC06044 IEK -0.472910919 -1.852406259 0.852557476 -4.447652564 1.572572328 0.947616583 FBgn0039326 CG10562 - http://flybase.org/reports/FBgn0039326 protein_coding_gene - - - CG10562 "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG10562 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.8, Cele\dhs-27, Cele\C29F7.1, Cele\nhr-246, Cele\F59B1.10, Cele\C29F7.2, Cele\H06H21.8" - - - "viable,visible" mesothoracic tergum FBgn0001842 l(1)ts1704 lethal (1) ts1704 http://flybase.org/reports/FBgn0001842 - gene - - - l(1)ts1704 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0022105 l(2)k07109a lethal (2) k07109a http://flybase.org/reports/FBgn0022105 - gene - - - "l(2)k07109, l(2)k07109a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016715 Reg-2 Rhythmically expressed gene 2 http://flybase.org/reports/FBgn0016715 - protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR006439 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 - "CG3200, Dreg-2, Reg-2, 21483246" "IPR011949:HAD-superfamily hydrolase, subfamily IA, REG-2-like, IPR006439:HAD hydrolase, subfamily IA, IPR023214:HAD-like domain" CG3200 11-Aug-17 DroID_v2017_08 "Drer\nanp, Drer\ephx2, Drer\hdhd3" Scer\YMR130W Cele\K01G5.10 "Xtro\nanp, Xtro\hdhd3, Xtro\acad10, Xtro\ephx2" "Mmus\Nanp, Mmus\Acad10, Mmus\Ephx2, Mmus\Hdhd3" "Hsap\EPHX2, Hsap\NANP, Hsap\ACAD10, Hsap\HDHD3" adult stage viable FBgn0036057 CG14164 - http://flybase.org/reports/FBgn0036057 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - CG14164 IPR019181:Anticodon-binding domain CG14164 11-Aug-17 DroID_v2017_08 "Drer\lsm12a, Drer\lsm12b" Scer\LSM12 Cele\M142.5 Xtro\lsm12 Mmus\Lsm12 Hsap\LSM12 FBgn0267597 CR45935 - http://flybase.org/reports/FBgn0267597 non_protein_coding_gene - - - "CR45935, lincRNA.600" - CR45935 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266251 CR44946 - http://flybase.org/reports/FBgn0266251 non_protein_coding_gene - - - "CR44946, lincRNA.805, R5_3R:14200046..14202222" - CR44946 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000975 fs(2)HO100 female sterile (2) HO100 http://flybase.org/reports/FBgn0000975 - gene - - - "fs(2)100A, fs(2)HO100" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" ovary FBgn0038469 CG4009 - http://flybase.org/reports/FBgn0038469 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 chorion ; GO:0042600 | inferred from direct assay CG4009 "IPR010255:Haem peroxidase, IPR029585:Peroxidase, insect, IPR019791:Haem peroxidase, animal" CG4009 11-Aug-17 DroID_v2017_08 "Drer\ptgs2b, Drer\igsf9bb, Drer\ptgs2a, Drer\tpo, Drer\ptgs1" - "Cele\C46A5.4, Cele\mlt-7, Cele\R08F11.7, Cele\F09F3.5, Cele\K10B4.1, Cele\T06D8.10, Cele\skpo-2, Cele\skpo-3" "Xtro\tpo, Xtro\ptgs1, Xtro\ptgs2, Xtro\epx, Xtro\mpo, Xtro\pxdn" "Mmus\Pxdn, Mmus\Epx, Mmus\Mpo, Mmus\Ptgs1, Mmus\Tpo, Mmus\Lpo, Mmus\Ptgs2" "Hsap\EPX, Hsap\PTGS2, Hsap\TPO, Hsap\PTGS1, Hsap\MPO, Hsap\LPO, Hsap\PXDNL, Hsap\PXDN" viable FBgn0013339 Spf Spadefoot http://flybase.org/reports/FBgn0013339 - gene - - - Spf - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" FBgn0053511 CG33511 - http://flybase.org/reports/FBgn0053511 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14398, CG33511" "IPR011009:Protein kinase-like domain, IPR004119:Protein of unknown function DUF227, IPR015897:CHK kinase-like" CG33511 11-Aug-17 DroID_v2017_08 - - "Cele\F59B1.10, Cele\C29F7.1, Cele\dhs-27, Cele\H06H21.8, Cele\T16G1.3, Cele\C04F6.7, Cele\C29F7.2, Cele\nhr-246" - - - FBgn0058236 CG40236 - http://flybase.org/reports/FBgn0058236 protein_coding_gene - - - CG40236 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262065 SG16 - http://flybase.org/reports/FBgn0262065 gene - - - SG16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031659 CG14043 - http://flybase.org/reports/FBgn0031659 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:Q96EK5 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q96EK5 CG14043 "IPR011990:Tetratricopeptide-like helical domain, IPR022083:KIF-1 binding protein" CG14043 11-Aug-17 DroID_v2017_08 Drer\kif1bp - - Xtro\kif1bp Mmus\Kif1bp Hsap\KIF1BP viable FBgn0000517 dw-24E dwarf 24F http://flybase.org/reports/FBgn0000517 - gene - - - "dw-24F, dw-24E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced,fertile" "adult abdomen,adult thorax,eye,wing,macrochaeta" FBgn0267516 pre-rRNA-Psi:CR45856 ribosomal RNA primary transcript pseudogene:CR45856 http://flybase.org/reports/FBgn0267516 pseudogene_attribute - - - "pre-rRNA-Psi:CR45856, CR45856" - CR45856 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051055 CG31055 - http://flybase.org/reports/FBgn0051055 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs23c05.y1, NEST:bs23c05, NEST:bs01f03, BcDNA:AT11054, BcDNA:AT22836, CG31055" - CG31055 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031219 CG13694 - http://flybase.org/reports/FBgn0031219 protein_coding_gene - - - CG13694 IPR002350:Kazal domain CG13694 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053202 dpr11 defective proboscis extension response 11 http://flybase.org/reports/FBgn0053202 protein_coding_gene molecular_function ; GO:0003674 | no biological data available photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype regulation of neuromuscular junction development ; GO:1904396 | inferred from mutant phenotype sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype establishment of synaptic specificity at neuromuscular junction ; GO:0007529 | inferred from direct assay synapse organization ; GO:0050808 | inferred from expression pattern neuron projection membrane ; GO:0032589 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG33202, CG15183, Dpr-11, CG31309, CT35098, CG15182, CG15181, BcDNA:GH22307, dpr11, Dpr11" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG33202 11-Aug-17 DroID_v2017_08 "Drer\lrit1b, Drer\itgb4, Drer\kirrel3a, Drer\dscama, Drer\lrit3b, Drer\ncam1b, Drer\si:dkey-65b12.12, Drer\kirrel3l, Drer\si:ch1073-459j12.1, Drer\si:ch211-264f5.6, Drer\sdk1a, Drer\kirrelb, Drer\kirrel3b, Drer\igsf9a, Drer\LOC101885725, Drer\paplna, Drer\igsf9bb, Drer\LOC100333196, Drer\lrit3a, Drer\si:ch211-163c2.2, Drer\kirrela, Drer\sdk1b, Drer\lrit1a, Drer\ush2a, Drer\LOC101885444" - Cele\zig-8 "Xtro\cadm2, Xtro\obsl1, Xtro\kirrel2, Xtro\igsf9b, Xtro\papln, Xtro\lrit3, Xtro\nfasc" "Mmus\Ptprq, Mmus\Amica1, Mmus\Papln, Mmus\Lrit3, Mmus\Sdk1, Mmus\Igsf9b, Mmus\Kirrel3, Mmus\Kirrel, Mmus\Lrit1, Mmus\Kirrel2" "Hsap\KIRREL, Hsap\KIRREL3, Hsap\IGSF9B, Hsap\KIRREL2, Hsap\USH2A, Hsap\LRIT3, Hsap\PAPLN, Hsap\SDK1, Hsap\LRIT1" "viable,fertile" FBgn0046225 CG17230 - http://flybase.org/reports/FBgn0046225 protein_coding_gene - - - "BcDNA:GH24095, CG5286, CG17230" IPR026773:Trichoplein keratin filament-binding protein CG17230 11-Aug-17 DroID_v2017_08 "Drer\cfap53, Drer\tchp" - - Xtro\tchp "Mmus\Tchp, Mmus\Cfap53" "Hsap\IVL, Hsap\CFAP53, Hsap\TCHP" viable FBgn0036830 CG14077 - http://flybase.org/reports/FBgn0036830 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000161400 enzyme regulator activity ; GO:0030234 | inferred from biological aspect of ancestor with PANTHER:PTN000161400 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000161400 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000161400" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000161401 "VIa, CG14077" "IPR001349:Cytochrome c oxidase, subunit VIa" CG14077 11-Aug-17 DroID_v2017_08 "Drer\cox6a1, Drer\cox6a2" Scer\COX13 Cele\tag-174 "Xtro\cox6a2, Xtro\cox6a1" "Mmus\Cox6a2, Mmus\Cox6a1" "Hsap\COX6A1, Hsap\COX6A2" viable DRSC10082 K -0.669673064 0.96390079 -0.368771524 0.802115012 1.724375166 -0.645718191 FBgn0060333 l(3)S145609 lethal (3) S145609 http://flybase.org/reports/FBgn0060333 gene - - - "1456/09, l(3)S145609" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0067097 H71 H71 http://flybase.org/reports/FBgn0067097 gene - - - H71 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable" FBgn0065275 l(2)SH2049 lethal (2) SH2049 http://flybase.org/reports/FBgn0065275 gene - - - "l(2)SH2049, l(2)SH2 2049" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082947 snoRNA:Me18S-U1356c snoRNA:Me18S-U1356c http://flybase.org/reports/FBgn0082947 snoRNA_gene - - - "snoRNA:Me18S-U1356c, Me18S-Um1356c, CR34646" - CR34646 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266095 CR44832 - http://flybase.org/reports/FBgn0266095 non_protein_coding_gene - - - CR44832 - CR44832 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051109 CG31109 - http://flybase.org/reports/FBgn0051109 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG13649, BcDNA:RE17222, CG31109" "IPR012934:Zinc finger, AD-type" CG31109 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0265103 CR44205 - http://flybase.org/reports/FBgn0265103 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44205, CR44205" - CR44205 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030925 Hayan Hayan http://flybase.org/reports/FBgn0030925 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model regulation of melanization defense response ; GO:0035007 | inferred from mutant phenotype" - "SP31, c-SP31, Hayan, CG6361" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site, IPR022700:Proteinase, regulatory CLIP domain" CG6361 11-Aug-17 DroID_v2017_08 - - "Cele\svh-1, Cele\try-3" - - - "short lived,conditional,viable,fertile,wound healing defective,partially lethal - majority die,some die during larval stage" trachea FBgn0027305 l(1)G0120 lethal (1) G0120 http://flybase.org/reports/FBgn0027305 - gene - - - "l(1)G0120, l(1)G01290" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065980 iab-6-1.as iab-6-1.as http://flybase.org/reports/FBgn0065980 gene - - - "6-1 as, iab-6-1.as" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034096 CG7786 - http://flybase.org/reports/FBgn0034096 protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from biological aspect of ancestor with PANTHER:PTN000945219 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000945219 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR004827 multicellular organism development ; GO:0007275 | inferred from biological aspect of ancestor with PANTHER:PTN000945219" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000945219 "CG7786, DM7, DM33" IPR004827:Basic-leucine zipper domain CG7786 11-Aug-17 DroID_v2017_08 "Drer\cebpb, Drer\cebp1, Drer\hlfb, Drer\si:dkey-172o19.2, Drer\dbpa, Drer\ddit3, Drer\nfil3-2, Drer\hlfa, Drer\nfil3-4, Drer\nfil3-5, Drer\tefa, Drer\dbpb, Drer\tefb" - "Cele\zip-6, Cele\atf-2, Cele\ces-2, Cele\atf-8, Cele\zip-7" "Xtro\tef, Xtro\cebpb, Xtro\hlf, Xtro\dbp" "Mmus\Dbp, Mmus\Cebpb, Mmus\Hlf, Mmus\Cebpe, Mmus\Cebpa, Mmus\Tef" "Hsap\TEF, Hsap\HLF, Hsap\DBP, Hsap\CEBPA" viable FBgn0032490 CG16813 - http://flybase.org/reports/FBgn0032490 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from sequence or structural similarity - - "CG16813, DM26" - CG16813 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032733 CG15170 - http://flybase.org/reports/FBgn0032733 protein_coding_gene - wound healing ; GO:0042060 | inferred from mutant phenotype - CG15170 IPR008472:Domain of unknown function DUF753 CG15170 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265819 CR44608 - http://flybase.org/reports/FBgn0265819 non_protein_coding_gene - - - "lincRNA.31, CR44608, R5_2L:4228805..4232740" - CR44608 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000918 fs(1)ne4 female sterile (1) no eggs 4 http://flybase.org/reports/FBgn0000918 - gene - - - "ne4, fs(1)ne[4], fs(1)ne4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,female sterile germline-dependent" "dorsal appendage,chorion,endochorion,oocyte" FBgn0003493 spw spur wing http://flybase.org/reports/FBgn0003493 - gene - - - spw - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,wing vein" FBgn0038028 CG10035 - http://flybase.org/reports/FBgn0038028 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "clone 20, anon-EST:Liang-20, CG10035" - CG10035 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" FBgn0017383 l(1)1Ai lethal (1) 1Ai http://flybase.org/reports/FBgn0017383 - gene - - - "HM17, l(1)1Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025774 l(2)k04206 lethal (2) k04206 http://flybase.org/reports/FBgn0025774 - gene - - - l(2)k04206 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263566 mir-4909 mir-4909 stem loop http://flybase.org/reports/FBgn0263566 miRNA_gene - - - "mir-4909, dme-mir-4909, CR43551" - CR43551 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061042 l(3)S023733 lethal (3) S023733 http://flybase.org/reports/FBgn0061042 gene - - - "0237/33, l(3)S023733" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266897 CR45357 - http://flybase.org/reports/FBgn0266897 non_protein_coding_gene - - - CR45357 - CR45357 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266372 CR45016 - http://flybase.org/reports/FBgn0266372 non_protein_coding_gene - - - CR45016 - CR45016 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266312 CR44977 - http://flybase.org/reports/FBgn0266312 non_protein_coding_gene - - - CR44977 - CR44977 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001974 l(2)35Bd lethal (2) 35Bd http://flybase.org/reports/FBgn0001974 FBgn0027886 protein_coding_gene mRNA (guanine-N7-)-methyltransferase activity ; GO:0004482 | inferred from biological aspect of ancestor with PANTHER:PTN000257091 mRNA (guanine-N7-)-methyltransferase activity ; GO:0004482 | inferred from sequence or structural similarity with UniProtKB:O43148 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:O43148 mRNA (guanine-N7-)-methyltransferase activity ; GO:0004482 | inferred from sequence or structural similarity RNA (guanine-N7)-methylation ; GO:0036265 | inferred from biological aspect of ancestor with PANTHER:PTN000257091 7-methylguanosine mRNA capping ; GO:0006370 | inferred from sequence or structural similarity with UniProtKB:O43148 7-methylguanosine mRNA capping ; GO:0006370 | inferred from biological aspect of ancestor with PANTHER:PTN000257091 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:O43148 mRNA cap binding complex ; GO:0005845 | inferred from biological aspect of ancestor with PANTHER:PTN000257091 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000257091 "l(2)10408, BG:DS00929.5, l(2)br9, br9, C2, CG3688, l(2)35Bd" "IPR004971:mRNA (guanine-N(7))-methyltransferase domain, IPR016899:mRNA (guanine-N(7))-methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG3688 11-Aug-17 DroID_v2017_08 Drer\rnmt Scer\ABD1 Cele\tag-72 Xtro\rnmt Mmus\Rnmt Hsap\RNMT "lethal,recessive,viable,visible" mesothoracic tergum FBgn0027968 l(3)S144607b lethal (3) S144607b http://flybase.org/reports/FBgn0027968 gene - - - "1446/07, l(3)S144607, l(3)S144607b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0085231 CG34202 - http://flybase.org/reports/FBgn0085231 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34202 - CG34202 11-Aug-17 DroID_v2017_08 Drer\si:ch1073-340i21.3 - - - - - FBgn0005052 flu fluorouracil response http://flybase.org/reports/FBgn0005052 - gene - - - flu - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,chemical resistant" FBgn0037756 CG8507 - http://flybase.org/reports/FBgn0037756 protein_coding_gene low-density lipoprotein particle receptor binding ; GO:0050750 | inferred from electronic annotation with InterPro:IPR010483 heparin binding ; GO:0008201 | inferred from electronic annotation with InterPro:IPR010483 - endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR010483 endomembrane system ; GO:0012505 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay CG8507 "IPR009066:Alpha-2-macroglobulin receptor-associated protein, domain 1, IPR010483:Alpha-2-macroglobulin RAP, C-terminal" CG8507 11-Aug-17 DroID_v2017_08 Drer\lrpap1 - Cele\C15C8.4 Xtro\lrpap1 Mmus\Lrpap1 Hsap\LRPAP1 viable FBgn0038147 CCHa2 CCHamide-2 http://flybase.org/reports/FBgn0038147 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model inferred from direct assay "BcDNA:RE10132, CG14375, CCHa2, Dm-CCHa2, CCM, CCH2, CCHamide-2" - CG14375 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065626 l(2)SH0794 lethal (2) SH0794 http://flybase.org/reports/FBgn0065626 gene - - - "l(2)SH0794, l(2)SH2 0794" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264571 CR43943 - http://flybase.org/reports/FBgn0264571 non_protein_coding_gene - - - CR43943 - CR43943 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065983 iab-5-1.s iab-5-1.s http://flybase.org/reports/FBgn0065983 gene - - - "5-1 s, iab-5-1.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052591 CG32591 - http://flybase.org/reports/FBgn0052591 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs18d12, NEST:bs09h01, CG32591" "IPR027710:Enkurin domain-containing protein 1, IPR027012:Enkurin domain" CG32591 11-Aug-17 DroID_v2017_08 Drer\si:ch211-220d9.3 - - Xtro\enkd1 Mmus\Enkd1 Hsap\ENKD1 FBgn0038205 Kif19A Kinesin family member 19A http://flybase.org/reports/FBgn0038205 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "CG9913, DmKIF19A, Kif19A, DmKlp19A, KIF19A, KIF 19A" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9913 11-Aug-17 DroID_v2017_08 "Drer\kif18a, Drer\cenpe, Drer\kif22, Drer\kif19, Drer\si:dkey-26i13.8" "Scer\KIP3, Scer\KIP2" Cele\klp-13 "Xtro\kif18b, Xtro\kif19, Xtro\kif18a, Xtro\kif22, Xtro\cenpe" "Mmus\Kif22, Mmus\LOC101055939, Mmus\Kif18a, Mmus\Kif19a, Mmus\Kif18b, Mmus\Cenpe" "Hsap\CENPE, Hsap\GPR142, Hsap\KIF22, Hsap\KIF19, Hsap\KIF18B, Hsap\KIF18A" viable FBgn0013481 l(1)1PP22 lethal (1) 1PP22 http://flybase.org/reports/FBgn0013481 - gene - - - l(1)1PP22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect" "epidermis,germline clone,ventral" FBgn0065478 l(2)SH1296 lethal (2) SH1296 http://flybase.org/reports/FBgn0065478 gene - - - "l(2)SH1296, l(2)SH2 1296" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032897 CG9336 - http://flybase.org/reports/FBgn0032897 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE71975, CG9336" - CG9336 11-Aug-17 DroID_v2017_08 - - "Cele\K11H12.7, Cele\K11H12.6, Cele\C15H9.9" - - - "viable,body color defective" mesothoracic tergum FBgn0045037 scc split central complex http://flybase.org/reports/FBgn0045037 gene - brain development ; GO:0007420 | inferred from mutant phenotype - scc - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "ellipsoid body,fan-shaped body" FBgn0027173 l(2)7-1 lethal (2) 7-1 http://flybase.org/reports/FBgn0027173 - gene - - - l(2)7-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023109 anon-10Ay anon-10Ay http://flybase.org/reports/FBgn0023109 - gene - - - "18, anon-10Ay" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266902 CR45362 - http://flybase.org/reports/FBgn0266902 non_protein_coding_gene - - - CR45362 - CR45362 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038076 Cyp313a4 Cyp313a4 http://flybase.org/reports/FBgn0038076 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" - "313a4, CG6802, Cyp313a4, Cyp313A4" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG6802 11-Aug-17 DroID_v2017_08 "Drer\cyp46a1.3, Drer\LOC100329425, Drer\zgc:123299, Drer\cyp26b1, Drer\cyp20a1, Drer\cyp4f3, Drer\cyp46a1.1, Drer\cyp46a1.4, Drer\cyp26c1, Drer\cyp4v7, Drer\cyp46a1.2, Drer\cyp26a1, Drer\cyp4v8, Drer\cyp19a1a, Drer\cyp19a1b, Drer\cyp4t8" "Scer\DIT2, Scer\ERG5, Scer\ERG11" - "Xtro\cyp20a1, Xtro\cyp4f2, Xtro\cyp4v2, Xtro\cyp26b1, Xtro\cyp4b1, Xtro\cyp26a1, Xtro\cyp19a1, Xtro\cyp26c1, Xtro\cyp4f22, Xtro\mgc108213, Xtro\cyp4b1.2, Xtro\LOC100488227, Xtro\LOC100487918" "Mmus\Cyp4f16, Mmus\Cyp26b1, Mmus\Cyp46a1, Mmus\Cyp26c1, Mmus\Cyp4a12b, Mmus\Cyp4x1, Mmus\Cyp4v3, Mmus\Cyp4f14, Mmus\Cyp4b1, Mmus\Cyp4a31, Mmus\Cyp4f37, Mmus\Cyp4f17, Mmus\Cyp4a32, Mmus\Cyp4f18, Mmus\Cyp26a1, Mmus\Cyp4f40, Mmus\Cyp20a1, Mmus\Cyp4a10, Mmus\Cyp4f15, Mmus\Cyp19a1, Mmus\Cyp4f13, Mmus\Cyp4f39, Mmus\Cyp4a14, Mmus\Cyp4a12a" "Hsap\CYP4B1, Hsap\CYP46A1, Hsap\CYP4F11, Hsap\CYP4F12, Hsap\CYP26B1, Hsap\CYP4Z1, Hsap\CYP4F2, Hsap\CYP20A1, Hsap\CYP26A1, Hsap\CYP4F3, Hsap\CYP26C1, Hsap\CYP4V2, Hsap\CYP19A1, Hsap\CYP4X1, Hsap\CYP4A11, Hsap\CYP4A22, Hsap\CYP4F22" FBgn0030643 CG15641 - http://flybase.org/reports/FBgn0030643 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG15641 - CG15641 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19677 I 1.834890459 0.154324858 0.305928813 0.456902712 0.383329122 0.182856077 FBgn0032530 CG9263 - http://flybase.org/reports/FBgn0032530 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9263 - CG9263 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020874 anon-M8 anon-M8 http://flybase.org/reports/FBgn0020874 - gene - - - "2-M8, anon-M8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0032050 CG13096 - http://flybase.org/reports/FBgn0032050 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 cytosolic large ribosomal subunit ; GO:0022625 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 CG13096 "IPR023674:Ribosomal protein L1-like, IPR028364:Ribosomal protein L1/ribosomal biogenesis protein, IPR016095:Ribosomal protein L1, 3-layer alpha/beta-sandwich" CG13096 11-Aug-17 DroID_v2017_08 "Drer\rpl10a, Drer\rsl1d1" "Scer\TOS4, Scer\RPL1A, Scer\CIC1, Scer\RPL1B, Scer\UTP30" "Cele\rpl-1, Cele\mrpl-1, Cele\F53F4.11" - "Mmus\Rpl10a, Mmus\Rsl1d1" "Hsap\RPL10A, Hsap\RSL1D1" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0004621 l(2)hs lethal heat-sensitive http://flybase.org/reports/FBgn0004621 - gene - - - l(2)hs - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0020617 Rx Retinal Homeobox http://flybase.org/reports/FBgn0020617 "FBgn0000530, FBgn0003998, FBgn0005641" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR032967 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970" "transcription from RNA polymerase II promoter ; GO:0006366 | inferred from electronic annotation with InterPro:IPR032967 visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR032967 camera-type eye development ; GO:0043010 | inferred from electronic annotation with InterPro:IPR032967 regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "drx, CG10052, DRx, Drx, W60, bk50, PPH17, E97, wom, Rx, rx" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR003654:OAR domain, IPR009057:Homeobox domain-like, IPR032967:Retinal homeobox protein Rx" CG10052 11-Aug-17 DroID_v2017_08 "Drer\rx1, Drer\arxa, Drer\rx2, Drer\alx1, Drer\alx4a, Drer\rx3, Drer\alx3" - "Cele\ceh-8, Cele\alr-1, Cele\ceh-10" "Xtro\arx, Xtro\alx1, Xtro\alx4, Xtro\rax" "Mmus\Alx3, Mmus\Rax, Mmus\Arx, Mmus\Alx4" "Hsap\ALX4, Hsap\ALX3, Hsap\ALX1, Hsap\ARX, Hsap\RAX2, Hsap\RAX" " embryonic stage | stage 10-11 , embryonic stage | stage >=13 , embryonic stage | stage >=11 , embryonic stage | stage >=8 " " eye disc | primordium

, antenno-maxillary complex

, embryonic central nervous system

, embryonic procephalic segment

, labral segment

" " embryonic stage | stage 13 , larval stage | third instar , adult stage " " adult clypeo-labral primordium

, embryonic brain | medial & restricted

, larval brain | medial & restricted

, brain | dorsal & posterior & restricted

, clypeo-labral disc | restricted

" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC03837 E -0.315416541 0.333019043 0.959948549 -2.256926715 0.941995902 -0.150906432 FBgn0038790 MtnC Metallothionein C http://flybase.org/reports/FBgn0038790 protein_coding_gene metal ion binding ; GO:0046872 | inferred from direct assay response to metal ion ; GO:0010038 | inferred from direct assay metal ion homeostasis ; GO:0055065 | inferred from mutant phenotype response to metal ion ; GO:0010038 | inferred from sequence or structural similarity with MtnE cellular_component ; GO:0005575 | no biological data available "CG5097, MtnC" "IPR000966:Metallothionein, family 5, Diptera" CG5097 11-Aug-17 DroID_v2017_08 - "Scer\CUP1-1, Scer\CUP1-2" - - - - viable FBgn0011710 Sep1 Septin 1 http://flybase.org/reports/FBgn0011710 "FBgn0005665, FBgn0013404, FBgn0014082, FBgn0024226" protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from direct assay GTP binding ; GO:0005525 | inferred from direct assay GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with pnut GTPase activity ; GO:0003924 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with sip2 ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with park cellularization ; GO:0007349 | traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from sequence or structural similarity positive regulation of apoptotic process ; GO:0043065 | inferred from direct assay "septin complex ; GO:0031105 | inferred from physical interaction with Sep1, pnut septin complex ; GO:0031105 | inferred from physical interaction with pnut, Sep2 septin ring ; GO:0005940 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay septin complex ; GO:0031105 | inferred from direct assay contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay" "sep1, CG1403, iby, tu1, anon-19Fa, Diff6, Sep1, 38960, DSep1, dSEPT1" "IPR030379:Septin-type guanine nucleotide-binding (G) domain, IPR016491:Septin, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1403 11-Aug-17 DroID_v2017_08 "Drer\sept15, Drer\sept5a, Drer\sept4b, Drer\zgc:162239, Drer\sept8a, Drer\sept2, Drer\zgc:63587, Drer\sept7b, Drer\sept3, Drer\sept4a, Drer\sept6, Drer\sept12, Drer\sept7a, Drer\sept5b, Drer\sept10, Drer\sept8b" "Scer\CDC11, Scer\SHS1, Scer\SPR3, Scer\SPR28, Scer\CDC3, Scer\CDC12, Scer\CDC10" "Cele\unc-61, Cele\unc-59" "Xtro\sept11, Xtro\sept10, Xtro\sept7, Xtro\sept8, Xtro\sept6, Xtro\sept5, Xtro\sept2-a, Xtro\sept2" "Mmus\Sept5, Mmus\Sept10, Mmus\Sept2, Mmus\Sept6, Mmus\Sept3, Mmus\Sept9, Mmus\Sept4, Mmus\Sept7, Mmus\Sept1, Mmus\Sept12, Mmus\Sept14, Mmus\Sept11, Mmus\Sept8" "Hsap\SEPT11, Hsap\SEPT1, Hsap\SEPT10, Hsap\SEPT2, Hsap\SEPT4, Hsap\SEPT3, Hsap\SEPT14, Hsap\SEPT8, Hsap\C9orf69, Hsap\SEPT5, Hsap\SEPT7, Hsap\SEPT9, Hsap\SEPT12, Hsap\SEPT6" embryonic stage -- adult stage viable FBgn0021751 3R-C 3R-C http://flybase.org/reports/FBgn0021751 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-C - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing,somatic clone,wing vein" FBgn0063422 l(3)3450-A lethal (3) 3450-A http://flybase.org/reports/FBgn0063422 gene - - - l(3)3450-A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0261834 CG42766 - http://flybase.org/reports/FBgn0261834 protein_coding_gene - - - "CG42766, FBgn0261834" - CG42766 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046657 anon-38C.56 anon-38C.56 http://flybase.org/reports/FBgn0046657 gene - - - "38C.56, anon-38C.56" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263948 BG00761 - http://flybase.org/reports/FBgn0263948 gene - - - BG00761 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,starvation stress response defective,gravitaxis defective" FBgn0030991 CG7453 - http://flybase.org/reports/FBgn0030991 protein_coding_gene - - - CG7453 - CG7453 11-Aug-17 DroID_v2017_08 "Drer\mansc1, Drer\wu:fa25f02" - - - "Mmus\1810055G02Rik, Mmus\Mansc4, Mmus\Mansc1" "Hsap\C11orf24, Hsap\MANSC4, Hsap\MANSC1" viable FBgn0261682 CG42729 - http://flybase.org/reports/FBgn0261682 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG42729, CG7973, CG17014, CG33984" IPR002557:Chitin binding domain CG42729 11-Aug-17 DroID_v2017_08 - - "Cele\W03F11.1, Cele\cbd-1" - - - FBgn0264705 CR43974 - http://flybase.org/reports/FBgn0264705 non_protein_coding_gene - - - CR43974 - CR43974 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041238 Gr58b Gustatory receptor 58b http://flybase.org/reports/FBgn0041238 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr58A2, 58A2, 58A.2, GR58A.2, CG13495, Gr58b" IPR013604:7TM chemoreceptor CG13495 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0267226 CR45666 - http://flybase.org/reports/FBgn0267226 non_protein_coding_gene - - - CR45666 - CR45666 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061056 l(3)S022558 lethal (3) S022558 http://flybase.org/reports/FBgn0061056 gene - - - "0225/58, l(3)S022558" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040063 yip3 yippee interacting protein 3 http://flybase.org/reports/FBgn0040063 protein_coding_gene threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353 proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from electronic annotation with InterPro:IPR001353 proteasome core complex ; GO:0005839 | inferred from electronic annotation with InterPro:IPR001353 "bs18b12.y1, NEST:bs18b12, CG13549, BcDNA:AT20887, yip3" "IPR001353:Proteasome, subunit alpha/beta, IPR029055:Nucleophile aminohydrolases, N-terminal" CG13549 11-Aug-17 DroID_v2017_08 - Scer\PUP1 - - - - "viable,fertile" DRSC04724 I 0.401612727 1.536688449 0.18715439 -0.504370684 1.472119323 0.98469622 FBgn0266376 CR45018 - http://flybase.org/reports/FBgn0266376 non_protein_coding_gene - - - CR45018 - CR45018 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086298 camo camouflaged http://flybase.org/reports/FBgn0086298 gene - - - camo - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite & filopodium & larva FBgn0022738 cnr censor http://flybase.org/reports/FBgn0022738 - gene - - - cnr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033275 CG14756 - http://flybase.org/reports/FBgn0033275 protein_coding_gene - - - CG14756 - CG14756 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0038715 CG7333 - http://flybase.org/reports/FBgn0038715 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG7333 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG7333 11-Aug-17 DroID_v2017_08 "Drer\slc22a5, Drer\slc22a21" "Scer\HXT2, Scer\PHO84, Scer\GIT1, Scer\HXT9, Scer\HXT5" "Cele\Y51A2D.18, Cele\C06H5.6, Cele\Y66D12A.13, Cele\C46C2.2, Cele\oct-1, Cele\C44C10.3, Cele\B0252.3, Cele\B0361.11, Cele\Y57G11C.23, Cele\ZK892.3, Cele\T22F7.1, Cele\C53B4.1" - "Mmus\Slc22a5, Mmus\Slc22a21, Mmus\Slc22a4" "Hsap\SLC22A4, Hsap\SLC22A5" "partially lethal - majority die,some die during pupal stage" FBgn0267218 CR45658 - http://flybase.org/reports/FBgn0267218 non_protein_coding_gene - - - CR45658 - CR45658 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260794 ctrip circadian trip http://flybase.org/reports/FBgn0260794 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018123 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12306 positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype positive regulation of circadian rhythm ; GO:0042753 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:12306 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:12306 "CG17735, CG14656, ctrip, CG42574, CTRIP" "IPR018123:WWE domain, subgroup, IPR000569:HECT domain, IPR004170:WWE domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG42574 11-Aug-17 DroID_v2017_08 "Drer\hectd1, Drer\trip12" Scer\UFD4 Cele\hecd-1 Xtro\trip12 "Mmus\Hectd1, Mmus\Trip12" "Hsap\TRIP12, Hsap\HECTD1" DRSC12242 E 0.693357252 -0.927077153 0.017965532 -3.364668582 -0.48129339 -0.801808619 FBgn0069173 mcl(3)Z0317 mcl(3)Z0317 http://flybase.org/reports/FBgn0069173 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z0317 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0264960 CR44129 - http://flybase.org/reports/FBgn0264960 non_protein_coding_gene - - - CR44129 - CR44129 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005245 l(3)R142 lethal of Roberts 142 http://flybase.org/reports/FBgn0005245 - gene - - - "l(3)B142, l(3)R142" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0042646 elav::Sxl elav::Sxl http://flybase.org/reports/FBgn0042646 engineered_fusion_gene - - - elav::Sxl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000805 fs(1)de16 female sterile (1) defective eggs 16 http://flybase.org/reports/FBgn0000805 - gene - - - "de16, fs(1)de16" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "endochorion,dorsal appendage,chorion" FBgn0039839 ppk24 pickpocket 24 http://flybase.org/reports/FBgn0039839 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG15555, ppk24, Ppk24" "IPR001873:Epithelial sodium channel, IPR020903:Epithelial sodium channel, conserved site" CG15555 11-Aug-17 DroID_v2017_08 "Drer\asic1c, Drer\asic1b, Drer\asic1a, Drer\asic4b, Drer\asic4a, Drer\asic2" - "Cele\delm-2, Cele\acd-1, Cele\degt-1, Cele\deg-1, Cele\acd-2, Cele\acd-5, Cele\acd-3, Cele\acd-4, Cele\delm-1, Cele\flr-1" "Xtro\asic4, Xtro\asic5, Xtro\scnn1b, Xtro\scnn1d, Xtro\scnn1a, Xtro\scnn1g, Xtro\asic1" "Mmus\Asic4, Mmus\Asic2, Mmus\Scnn1a, Mmus\Asic3, Mmus\Scnn1b, Mmus\Asic1, Mmus\Asic5, Mmus\Scnn1g" "Hsap\ASIC1, Hsap\ASIC5, Hsap\SCNN1A, Hsap\ASIC2, Hsap\SCNN1B, Hsap\ASIC3, Hsap\SCNN1D, Hsap\ASIC4, Hsap\SCNN1G" viable DRSC15093 I 1.06605634 4.087822039 1.334483322 0.343195714 0.426111986 -0.118601551 FBgn0052695 CG32695 - http://flybase.org/reports/FBgn0052695 protein_coding_gene - - - "CG15246, BcDNA:RH68724, CG32695" - CG32695 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0067652 sd-3 sd-3 http://flybase.org/reports/FBgn0067652 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032964 CG11630 - http://flybase.org/reports/FBgn0032964 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017850 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017850 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "gi7302136, CG11630" "IPR017850:Alkaline-phosphatase-like, core domain, IPR004245:Protein of unknown function DUF229, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG11630 11-Aug-17 DroID_v2017_08 - - "Cele\T23E1.1, Cele\K03A11.4, Cele\F32G8.2, Cele\F15H10.7, Cele\T07G12.3, Cele\R03G8.1, Cele\F10C2.3, Cele\Y73F8A.35, Cele\F32D8.2, Cele\Y41E3.1, Cele\R03G8.3, Cele\M03F8.5, Cele\Y38A10A.2, Cele\F07C3.3" - - - viable FBgn0063420 l(3)3450-C lethal (3) 3450-C http://flybase.org/reports/FBgn0063420 gene - - - l(3)3450-C - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0263618 CR43627 - http://flybase.org/reports/FBgn0263618 non_protein_coding_gene - - - "CR43627, lincRNA.437" - CR43627 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051520 CG31520 - http://flybase.org/reports/FBgn0051520 protein_coding_gene - - - CG31520 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265684 CR44491 - http://flybase.org/reports/FBgn0265684 non_protein_coding_gene - - - CR44491 - CR44491 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263596 CG43618 - http://flybase.org/reports/FBgn0263596 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43618 - CG43618 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260455 CG10332 - http://flybase.org/reports/FBgn0260455 protein_coding_gene - - - "CG10332-ORFA, BcDNA:AT19986, anon-WO0153538.58, anon-WO0153538.57, anon-WO0153538.56, CG10332" - CG10332 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065965 l(2)SH0022 lethal (2) SH0022 http://flybase.org/reports/FBgn0065965 gene - - - "l(2)SH0022, l(2)SH2 0022" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038052 CG5538 - http://flybase.org/reports/FBgn0038052 protein_coding_gene - - - "bs11a11.y1, anon-WO0140519.84, CG5538" - CG5538 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013812 Dhc93AB Dynein heavy chain at 93AB http://flybase.org/reports/FBgn0013812 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity sensory perception of sound ; GO:0007605 | inferred from mutant phenotype outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q8TE73 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "CG3723, dhc, DHC, Dhc, Dhc93AB, Dhc 93AB, dhc93AB, DHC4C" "IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain, IPR013594:Dynein heavy chain, domain-1" CG3723 11-Aug-17 DroID_v2017_08 "Drer\dnah7, Drer\si:dkeyp-86b9.1, Drer\dnah11, Drer\dnah12, Drer\dnah3, Drer\dnah2, Drer\dnah1, Drer\dync1h1, Drer\dnah7l, Drer\dnah9l, Drer\si:dkeyp-87a6.1, Drer\wu:fj30b09, Drer\dnah9" Scer\DYN1 "Cele\dhc-1, Cele\che-3" "Xtro\dnah7, Xtro\dnah2, Xtro\dnah14, Xtro\dnah9" "Mmus\Dnah11, Mmus\Dync1h1, Mmus\Dnah17, Mmus\Dnhd1, Mmus\Dnah7a, Mmus\Dnah2, Mmus\Dnah7b, Mmus\Dnah3, Mmus\Dync2h1, Mmus\Dnah1, Mmus\Dnah12, Mmus\Dnah9, Mmus\Dnah8, Mmus\Dnah5, Mmus\Dnah6, Mmus\Dnah10" "Hsap\DNAH12, Hsap\DNAH10, Hsap\DNAH7, Hsap\DNAH2, Hsap\DYNC1H1, Hsap\DNAH14, Hsap\DNAH11, Hsap\DNAH5, Hsap\DYNC2H1, Hsap\DNAH6, Hsap\DNAH1, Hsap\DNAH8, Hsap\DNAH9, Hsap\DNAH17, Hsap\DNAH3, Hsap\DNHD1, Hsap\CCDC88B" " adult stage | female , embryonic stage , adult stage | male " "auditory perception defective,neurophysiology defective,viable" FBgn0002578 Kaz-m1 Kazal-type protease inhibitor m1 http://flybase.org/reports/FBgn0002578 FBgn0063010 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from sequence model regulation of proteolysis ; GO:0030162 | inferred by curator from GO:0004867 cellular_component ; GO:0005575 | no biological data available "CG8342, HLHm1, E(spl)-m1, E(spl)m1, BcDNA:RE44854, Kaz-m1, m1, lincRNA.856" IPR002350:Kazal domain CG8342 11-Aug-17 DroID_v2017_08 - - Cele\ZK813.6 - - - " embryonic stage , embryonic stage | 6-10 hr " " posterior embryonic/larval midgut | anterior

, anterior embryonic/larval midgut | posterior

, embryonic/larval proventriculus

" viable FBgn0004563 l(3)63Bi lethal (3) 63Bi http://flybase.org/reports/FBgn0004563 - gene - - - l(3)63Bi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035137 CG1233 - http://flybase.org/reports/FBgn0035137 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG1233 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG1233 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-154p10.3, Drer\zbtb44, Drer\bcl6ab, Drer\zbtb48, Drer\zbtb46, Drer\hic2" - "Cele\pag-3, Cele\R10E4.11, Cele\Y55F3AM.14, Cele\blmp-1, Cele\ztf-16" Xtro\LOC733928 "Mmus\Zfp354c, Mmus\Zbtb49, Mmus\Zfp787, Mmus\Zbtb46, Mmus\Zfp316, Mmus\Prdm5" "Hsap\ZBTB49, Hsap\PRDM5, Hsap\ZBTB7C, Hsap\ZBTB10, Hsap\ZNF787, Hsap\ZNF316, Hsap\ZBTB46" viable FBgn0038273 CG14860 - http://flybase.org/reports/FBgn0038273 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612 - - CG14860 "IPR006612:Zinc finger, C2CH-type" CG14860 11-Aug-17 DroID_v2017_08 "Drer\zgc:153292, Drer\arl14ep, Drer\thap1, Drer\thap3, Drer\zgc:163143, Drer\znfl2a, Drer\LOC101883087, Drer\zgc:113364" - - Xtro\thap1 "Mmus\Thap1, Mmus\Thap3, Mmus\Thap2" "Hsap\THAP2, Hsap\THAP10, Hsap\THAP1, Hsap\THAP3" viable FBgn0004184 snRNA:U1:82Ec small nuclear RNA U1 at 82Ec http://flybase.org/reports/FBgn0004184 FBgn0003917 pseudogene_attribute - - - "U1, U1 snRNA, U1a-82Ec, 82.2, U1-82.2, U1 82E(pDm6Y), snRNA:U1, snRNA-U1-82.2, U1snRNA82Ec, snRNA:U1:82Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003665 tar tarry http://flybase.org/reports/FBgn0003665 - gene - - - "ta, tar" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced" "femur,tibia,leg,coxa" FBgn0052362 tRNA:Leu-CAG-1-6 transfer RNA:Leucine-CAG 1-6 http://flybase.org/reports/FBgn0052362 tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "CR32362, AE002602.trna6-LeuCAG, tRNA[Leu][[2]], tRNA:leu2:66B, tRNA:L2:66B, tRNA:L:CAG:AE002602-b, chr3L.trna40-LeuCAG, tRNA-Leu-CAG-1-6, tRNA:Leu-CAG-1-6, tRNA:CR32362, CUG" - CR32362 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014158 eppy epilated periorbitally http://flybase.org/reports/FBgn0014158 - gene - - - "eppy, Eps15" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013467 igl igloo http://flybase.org/reports/FBgn0013467 - protein_coding_gene calmodulin binding ; GO:0005516 | inferred from direct assay myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis - cell cortex ; GO:0005938 | inferred from direct assay "CG18285, igl, Igl" "IPR000048:IQ motif, EF-hand binding site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG18285 11-Aug-17 DroID_v2017_08 "Drer\nrgna, Drer\gap43, Drer\spa17" - "Cele\F39H12.3, Cele\ZK1320.13" Xtro\spa17 "Mmus\Spa17, Mmus\Gap43, Mmus\Nrgn" "Hsap\NRGN, Hsap\SPA17, Hsap\GAP43" " embryonic stage--pupal stage , embryonic stage | stage >=15 , embryonic stage -- adult stage " " embryonic peripheral nervous system

, central nervous system

" DRSC28961 K 0.553638708 -0.944848549 0.319138291 0.883986508 -0.378895205 -2.753896913 FBgn0065701 l(2)SH0621 lethal (2) SH0621 http://flybase.org/reports/FBgn0065701 gene - - - "l(2)SH0621, l(2)SH2 0621" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265871 CR44660 - http://flybase.org/reports/FBgn0265871 non_protein_coding_gene - - - CR44660 - CR44660 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036858 CG14088 - http://flybase.org/reports/FBgn0036858 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "SPH199, CG14088" "IPR009003:Peptidase S1, PA clan, IPR001254:Serine proteases, trypsin domain" CG14088 11-Aug-17 DroID_v2017_08 Drer\zgc:123217 - - - - Hsap\F7 viable FBgn0044378 anon-AE003538.1 anon-AE003538.1 http://flybase.org/reports/FBgn0044378 gene - - - anon-AE003538.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053627 CG33627 - http://flybase.org/reports/FBgn0053627 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33627 IPR010512:Protein of unknown function DUF1091 CG33627 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038652 CG7720 - http://flybase.org/reports/FBgn0038652 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "BcDNA:RH05973, CG7720, ORE-8, dSLC5A1" IPR001734:Sodium/solute symporter CG7720 11-Aug-17 DroID_v2017_08 "Drer\slc5a8l, Drer\slc5a9, Drer\slc5a6b, Drer\slc5a3a, Drer\slc5a11, Drer\LOC568338, Drer\slc5a2, Drer\si:dkeyp-9d4.5, Drer\slc5a6a, Drer\slc5a8, Drer\slc5a1, Drer\slc5a5, Drer\slc5a12" Scer\DUR3 Cele\F52H2.4 "Xtro\slc5a12, Xtro\slc5a2, Xtro\slc5a11, Xtro\slc5a9, Xtro\slc5a1.1, Xtro\slc5a5, Xtro\slc5a8" "Mmus\Slc5a2, Mmus\Slc5a1, Mmus\Slc5a10, Mmus\Slc5a8, Mmus\Slc5a12, Mmus\Slc5a11, Mmus\Slc5a4a, Mmus\Slc5a4b, Mmus\Gm5134, Mmus\Slc5a3, Mmus\Slc5a6, Mmus\Slc5a9, Mmus\Slc5a5" "Hsap\SLC5A11, Hsap\SLC5A3, Hsap\SLC5A4, Hsap\SLC5A6, Hsap\SLC5A10, Hsap\SLC5A1, Hsap\SLC5A5, Hsap\SLC5A8, Hsap\SLC5A2, Hsap\SLC5A9, Hsap\SLC5A12" "viable,fertile" FBgn0032779 CG16771 - http://flybase.org/reports/FBgn0032779 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG16771 "IPR001952:Alkaline phosphatase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG16771 11-Aug-17 DroID_v2017_08 "Drer\alpi.1, Drer\alpl, Drer\alp3, Drer\alpi.2" Scer\PHO8 - "Xtro\alpi.1, Xtro\alpl" "Mmus\Alppl2, Mmus\Akp3, Mmus\Alpi, Mmus\Alpl" "Hsap\ALPI, Hsap\ALPL, Hsap\ALPPL2, Hsap\ALPP" "viable,flightless" FBgn0036222 SdhAL "Succinate dehydrogenase, subunit A (flavoprotein)-like" http://flybase.org/reports/FBgn0036222 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR011281, InterPro:IPR014006 succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from biological aspect of ancestor with PANTHER:PTN000180259 succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from sequence or structural similarity with HGNC:10680 electron carrier activity ; GO:0009055 | inferred from biological aspect of ancestor with PANTHER:PTN000180228" "anaerobic respiration ; GO:0009061 | inferred from biological aspect of ancestor with PANTHER:PTN000180228 mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from biological aspect of ancestor with PANTHER:PTN000180258 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000180364 respiratory electron transport chain ; GO:0022904 | inferred from sequence or structural similarity with HGNC:10680" "mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from biological aspect of ancestor with PANTHER:PTN000180258" "CG5718, DHSA, SdhAL" "IPR003952:Fumarate reductase/succinate dehydrogenase, FAD-binding site, IPR003953:FAD-dependent oxidoreductase 2, FAD binding domain, IPR011281:Succinate dehydrogenase, flavoprotein subunit, IPR015939:Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal, IPR027477:Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain, IPR014006:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, IPR030664:Succinate dehydrogenase/fumarate reductase/adenylylsulphate reductase, flavoprotein subunit, IPR023753:FAD/NAD(P)-binding domain" CG5718 11-Aug-17 DroID_v2017_08 Drer\sdha "Scer\OSM1, Scer\SDH1, Scer\YJL045W, Scer\FRD1" "Cele\sdha-1, Cele\sdha-2" Xtro\sdha Mmus\Sdha Hsap\SDHA viable FBgn0030961 CG7058 - http://flybase.org/reports/FBgn0030961 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000698511 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 CG7058 "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain" CG7058 11-Aug-17 DroID_v2017_08 "Drer\spopla, Drer\klhl11, Drer\spop, Drer\kbtbd4, Drer\si:dkey-260j18.2, Drer\spoplb" Scer\YIL001W "Cele\bath-40, Cele\bath-43, Cele\bath-42, Cele\bath-41, Cele\hpo-9" "Xtro\kbtbd4, Xtro\spop" "Mmus\Gm10696, Mmus\Tdpoz5, Mmus\Gm4858, Mmus\Klhl11, Mmus\Gm9125, Mmus\Tdpoz1, Mmus\Tdpoz2, Mmus\Tdpoz4, Mmus\Kbtbd4, Mmus\Tdpoz3, Mmus\Spop, Mmus\Gm10697, Mmus\Spopl" "Hsap\KBTBD4, Hsap\SPOP, Hsap\KLHL11, Hsap\SPOPL" "partially lethal - majority die,some die during pupal stage" DRSC20021 K -0.128695932 -0.243223875 0.443894608 0.120395991 1.955790064 0.940835089 FBgn0036442 CG13473 - http://flybase.org/reports/FBgn0036442 protein_coding_gene "oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ; GO:0016671 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 thioredoxin-disulfide reductase activity ; GO:0004791 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 protein-disulfide reductase activity ; GO:0047134 | inferred from biological aspect of ancestor with PANTHER:PTN000047179" glycerol ether metabolic process ; GO:0006662 | inferred from electronic annotation with InterPro:IPR005746 cell redox homeostasis ; GO:0045454 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 cellular response to oxidative stress ; GO:0034599 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 CG13473 "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site, IPR005746:Thioredoxin" CG13473 11-Aug-17 DroID_v2017_08 "Drer\ahnak, Drer\zgc:56493, Drer\txn, Drer\txn2" "Scer\TRX3, Scer\TRX1, Scer\TRX2" "Cele\trx-4, Cele\trx-2, Cele\Y55F3AR.2, Cele\trx-1" "Xtro\LOC100498224, Xtro\nme9, Xtro\ahnak, Xtro\LOC100170420, Xtro\txn, Xtro\prx" "Mmus\Ahnak2, Mmus\Nme8, Mmus\Txndc8, Mmus\Ahnak, Mmus\Txn1, Mmus\Txn2, Mmus\Txndc2" "Hsap\TXNDC2, Hsap\TXN2, Hsap\TXN, Hsap\AHNAK, Hsap\TXNDC8, Hsap\AHNAK2, Hsap\NME8" viable FBgn0011280 Obp19d Odorant-binding protein 19d http://flybase.org/reports/FBgn0011280 "FBgn0062913, FBgn0063177" protein_coding_gene pheromone binding ; GO:0005550 | inferred from sequence or structural similarity pheromone binding ; GO:0005550 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "pbprp2, Obp19d, PBPRP-2, 19d, PBP2, CG1668, PBPRP2, pbprp-2, PB-PRP2, BcDNA:HL07789, BcDNA:RH68082, DmelObp19d, Pbprp2" IPR006170:Pheromone/general odorant binding protein CG1668 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " maxillary palpus

, sensillum coeloconica of antennal segment 3

, taste-sensory region glomerulus

, sensillum basiconicum of antennal segment 3

, antennal segment 3

, proboscis

, sensillum trichodeum of antennal segment 3

, ventral cibarial sense organ

" viable DRSC20569 K 0.541956213 -0.080552862 -0.000989213 0.217615473 1.100732064 1.846486009 FBgn0085805 CR41583 - http://flybase.org/reports/FBgn0085805 rRNA_gene - - - CR41583 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003260 Rm4 Ring magnifier on 4 http://flybase.org/reports/FBgn0003260 - gene - - - Rm4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020902 Su(osk)3-O26 Suppressor of oskar 3-O26 http://flybase.org/reports/FBgn0020902 - gene - - - "O26, Su(osk)3-O26" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000875 fs(1)M73 female sterile (1) M73 http://flybase.org/reports/FBgn0000875 - gene - - - fs(1)M73 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0065719 l(2)SH0573 lethal (2) SH0573 http://flybase.org/reports/FBgn0065719 gene - - - "l(2)SH0573, l(2)SH2 0573" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262477 FoxP Forkhead box P http://flybase.org/reports/FBgn0262477 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766 male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype operant conditioning ; GO:0035106 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "FoxP, CG43067, Dmcg16899, CG16899, CG32937, DmFoxP, fd85E, dFoxP" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR032354:FOXP, coiled-coil domain, IPR030456:Fork head domain conserved site 2" CG43067 11-Aug-17 DroID_v2017_08 "Drer\foxp3a, Drer\foxp2, Drer\foxp1b, Drer\foxp4, Drer\foxp3b, Drer\foxp1a" "Scer\HCM1, Scer\FKH2, Scer\FHL1, Scer\FKH1" "Cele\fkh-7, Cele\fkh-8" "Xtro\foxp1, Xtro\foxp4, Xtro\foxp2" "Mmus\Foxp2, Mmus\Foxp4, Mmus\Foxp3, Mmus\Foxp1" "Hsap\FOXP4, Hsap\FOXP1, Hsap\FOXP2, Hsap\FOXP3" DRSC29407 K -0.617406818 -0.26338598 0.731750493 -0.091460133 2.468415972 0.226901796 FBgn0267934 CR46214 - http://flybase.org/reports/FBgn0267934 non_protein_coding_gene - - - "CR46214, lincRNA.586" - CR46214 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032629 beat-IIIc beat-IIIc http://flybase.org/reports/FBgn0032629 protein_coding_gene molecular_function ; GO:0003674 | no biological data available motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype - "beat IIIc, CG6365, CG15138, BcDNA:RE14414, beat-IIIc, Beat-IIIC, Beat-IIIc" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG15138 11-Aug-17 DroID_v2017_08 "Drer\jam2b, Drer\zgc:172106, Drer\f11r.2" - - Xtro\f11r - Hsap\CADM2 viable FBgn0053306 CG33306 - http://flybase.org/reports/FBgn0053306 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG16887, BG:DS00941.11, DS00941.11, BcDNA:GM14937, CG33306" IPR010562:Haemolymph juvenile hormone binding CG33306 11-Aug-17 DroID_v2017_08 - - Cele\fbxa-14 - - - viable FBgn0001259 in inturned http://flybase.org/reports/FBgn0001259 - protein_coding_gene - establishment of planar polarity ; GO:0001736 | traceable author statement non-sensory hair organization ; GO:0035316 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "B, CG16993, in" IPR001478:PDZ domain CG16993 11-Aug-17 DroID_v2017_08 Drer\intu - - Xtro\intu Mmus\Intu Hsap\INTU "viable,fertile,visible,recessive,cold sensitive,wild-type,planar polarity defective,heat sensitive,lethal,cell autonomous,somatic clone" "macrochaeta,cold sensitive,wing cell,wing hair,microchaeta & wing,wing hair & 1st posterior cell,macrochaeta & adult thorax,microchaeta & adult thorax,microchaeta & leg,bract,wing,heat sensitive,supernumerary,cell autonomous,somatic clone" FBgn0261597 RpS26 Ribosomal protein S26 http://flybase.org/reports/FBgn0261597 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000892 mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000283756 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000892 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000892 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "RpS26, rpS31, rpS26, l(2)04553, anon-EST:fe2A3, CG10305, M(2)m, M[[s]], l(2)36Fa, M(2)S13, M(2)36F, Rps26" IPR000892:Ribosomal protein S26e CG10305 11-Aug-17 DroID_v2017_08 "Drer\rps26, Drer\rps26l" "Scer\RPS26A, Scer\RPS26B" Cele\rps-26 Xtro\rps26 Mmus\Rps26 "Hsap\LOC101929876, Hsap\LOC100996747, Hsap\RPS26" DRSC03420 IEK -2.27667225 -1.8482029 0.627828527 -3.618983175 -0.17589863 2.754710464 FBgn0085502 CG40624 - http://flybase.org/reports/FBgn0085502 protein_coding_gene - - - CG40624 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028882 tRNA:Pro-AGG-1-1 transfer RNA:Proline-AGG 1-1 http://flybase.org/reports/FBgn0028882 tRNA_gene CCU codon-amino acid adaptor activity ; GO:0033421 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033421 cytosol ; GO:0005829 | inferred by curator from GO:0033421 "BG:DS04641.2, tRNA:pro, AE002690.trna9-ProAGG, tRNA:P:AGG:AE002690-a, CR31985, chr2L.trna18-ProAGG, tRNA-Pro-AGG-1-1, tRNA:Pro-AGG-1-1, tRNA:P:35Bd, CCU" - CR31985 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265086 CR44197 - http://flybase.org/reports/FBgn0265086 non_protein_coding_gene - - - CR44197 - CR44197 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040772 CG12430 - http://flybase.org/reports/FBgn0040772 protein_coding_gene - - - CG12430 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069928 CG41123 - http://flybase.org/reports/FBgn0069928 protein_coding_gene - - - CG41123 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265711 CR44518 - http://flybase.org/reports/FBgn0265711 non_protein_coding_gene - - - "incRNA.445, CR44518, lincRNA.445" - CR44518 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266881 CR45342 - http://flybase.org/reports/FBgn0266881 non_protein_coding_gene - - - CR45342 - CR45342 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261832 CG42764 - http://flybase.org/reports/FBgn0261832 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42764 "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG42764 11-Aug-17 DroID_v2017_08 Drer\glipr2l - Cele\F57B7.2 - Mmus\Glipr2 Hsap\GLIPR2 FBgn0061045 l(3)S023637a lethal (3) S023637a http://flybase.org/reports/FBgn0061045 gene - - - "0236/37, l(3)S023637a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086707 ncm nucampholin http://flybase.org/reports/FBgn0086707 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000427685 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:Q9HCG8 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VHS8 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000427686 phagocytosis ; GO:0006909 | inferred from mutant phenotype" U2-type catalytic step 1 spliceosome ; GO:0071006 | inferred from biological aspect of ancestor with PANTHER:PTN000427686 catalytic step 2 spliceosome ; GO:0071013 | inferred from biological aspect of ancestor with PANTHER:PTN000427686 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with UniProtKB:Q9HCG8 "CG12750, E-2a, l(2)SH0931, ncm, l(2)SH2 0931, NCM" "IPR003891:Initiation factor eIF-4 gamma, MA3, IPR003890:MIF4G-like, type 3, IPR016024:Armadillo-type fold" CG12750 11-Aug-17 DroID_v2017_08 Drer\cwc22 Scer\CWC22 Cele\let-858 Xtro\cwc22 Mmus\Cwc22 Hsap\CWC22 DRSC02179 I -0.785395089 1.633931138 1.136503344 0.429024101 -0.693422318 -1.155720537 FBgn0065540 l(2)SH1061 lethal (2) SH1061 http://flybase.org/reports/FBgn0065540 gene - - - "l(2)SH1061, l(2)SH2 1061" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020772 vta vena transversa interrupta http://flybase.org/reports/FBgn0020772 - gene - - - vta - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005360 sup superwith http://flybase.org/reports/FBgn0005360 - gene - - - sup - - 11-Aug-17 DroID_v2017_08 - - - - - - body color defective trident FBgn0005463 l(1)ts66 lethal (1) ts66 http://flybase.org/reports/FBgn0005463 - gene - - - l(1)ts66 - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,lethal,heat sensitive,chemical sensitive,uncoordinated,gravitaxis defective,phototaxis defective,locomotor behavior defective,flight defective" FBgn0014042 Su(tor)2-113 Su(tor)2-113 http://flybase.org/reports/FBgn0014042 - gene - - - Su(tor)2-113 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051556 CG31556 - http://flybase.org/reports/FBgn0051556 protein_coding_gene - - - "CG31556, mdcds_43655" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC22177 IEK -1.568126033 2.028385134 2.089500495 1.741794365 2.326056651 0.104316319 FBgn0260968 CG42591 - http://flybase.org/reports/FBgn0260968 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42591 - CG42591 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033362 CG8172 - http://flybase.org/reports/FBgn0033362 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP32, c-SP32, CG8172" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG8172 11-Aug-17 DroID_v2017_08 "Drer\ela2l, Drer\zgc:112160, Drer\zgc:171592, Drer\si:dkey-238d18.3, Drer\si:dkey-16l2.17, Drer\ctrl, Drer\zgc:92511, Drer\zgc:92745, Drer\ctrb1, Drer\zgc:112368, Drer\zgc:92041, Drer\zgc:112302, Drer\zgc:112285, Drer\LOC562139, Drer\st14b, Drer\zgc:92313, Drer\ela2, Drer\si:dkey-57c15.4, Drer\ela3l, Drer\zgc:154142" - "Cele\try-1, Cele\try-3" "Xtro\cela2a, Xtro\cela3a, Xtro\LOC100135144, Xtro\ctrb2, Xtro\LOC101732100, Xtro\ctrb1" "Mmus\Cela2a, Mmus\Cela1, Mmus\Ctrl, Mmus\Prss22, Mmus\Prss41, Mmus\Ctrc, Mmus\Cela3b, Mmus\Cela3a, Mmus\Ctrb1" "Hsap\PRSS21, Hsap\CTRC, Hsap\CTRL, Hsap\PRSS48, Hsap\TMPRSS11D, Hsap\CELA2A, Hsap\CELA2B, Hsap\PRSS41, Hsap\CTRB2, Hsap\CELA3A, Hsap\CELA3B, Hsap\PRSS22, Hsap\CTRB1, Hsap\CELA1, Hsap\TMPRSS11B" FBgn0014228 l(2)31Eg lethal (2) 31Eg http://flybase.org/reports/FBgn0014228 - gene - - - l(2)31Eg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037669 Ibf2 Insulator binding factor 2 http://flybase.org/reports/FBgn0037669 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Cp190 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay regulation of gene expression ; GO:0010468 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from genetic interaction with w nucleus ; GO:0005634 | inferred from direct assay "Ibf2, CG9740" - CG9740 11-Aug-17 DroID_v2017_08 - - - - - - "homeotic,partially lethal - majority live,male sterile,short lived,dominant,viable" "abdominal sternite 7,female limited" FBgn0266437 CG45067 - http://flybase.org/reports/FBgn0266437 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from sequence model with InterPro:IPR008795 "CG45067, CG14955" - CG45067 11-Aug-17 DroID_v2017_08 "Drer\prom1b, Drer\prom2, Drer\prom1a" - Cele\prmn-1 "Xtro\prom2, Xtro\prom1" "Mmus\Prom1, Mmus\Prom2" "Hsap\PROM1, Hsap\PROM2" "viable,visible" mesothoracic tergum FBgn0036769 Tsp74F Tetraspanin 74F http://flybase.org/reports/FBgn0036769 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "Tsp74F, CG5492, Dm.Tsp74F" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG5492 11-Aug-17 DroID_v2017_08 "Drer\cd151, Drer\tspan35, Drer\tspan11, Drer\tspan34, Drer\tspan18b, Drer\cd151l, Drer\cd63, Drer\tspan18a" - "Cele\tsp-15, Cele\tsp-7, Cele\tsp-11, Cele\tsp-16" "Xtro\cd151, Xtro\tspan16, Xtro\tspan18, Xtro\tspan1" "Mmus\Tspan1, Mmus\Tspan18, Mmus\Cd63, Mmus\Cd151, Mmus\Tspan11" "Hsap\TSPAN1, Hsap\TSPAN18, Hsap\TSPAN11, Hsap\CD63, Hsap\CD151" "lethal,maternal effect,some die during embryonic stage,viable" "egg,maternal effect" FBgn0085316 CG34287 - http://flybase.org/reports/FBgn0085316 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34287 - CG34287 11-Aug-17 DroID_v2017_08 - - Cele\F31E9.3 - - - FBgn0000756 fs(1)A456 female sterile (1) A456 http://flybase.org/reports/FBgn0000756 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)456v24, fs(1)456, fs(1)M66, fs(1)A456" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,female sterile soma-dependent" egg FBgn0036394 CG9040 - http://flybase.org/reports/FBgn0036394 protein_coding_gene - - - "BcDNA:LP10528, CG9040" - CG9040 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0005762 l(1)TK409 lethal (1) TK409 http://flybase.org/reports/FBgn0005762 - gene - - - "l409, l(1)TK409" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0030495 CG11816 - http://flybase.org/reports/FBgn0030495 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11816 - CG11816 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19428 IE -2.00389823 -0.332720571 -1.79439505 -0.703366178 1.271309279 0.124621133 FBgn0030346 CG11802 - http://flybase.org/reports/FBgn0030346 protein_coding_gene - - - CG11802 "IPR018780:Tumour suppressor protein, LOH1CR12" CG11802 11-Aug-17 DroID_v2017_08 Drer\borcs5 - Cele\sam-4 Xtro\borcs5 Mmus\Borcs5 Hsap\BORCS5 viable FBgn0024541 l(3)L2100 lethal (3) L2100 http://flybase.org/reports/FBgn0024541 - gene - - - l(3)L2100 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005155 l(2)G99 lethal (2) G99 http://flybase.org/reports/FBgn0005155 - gene - - - l(2)G99 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003595 Su(var)3-4 Suppressor of variegation 3-4 http://flybase.org/reports/FBgn0003595 - gene - - - "Su(var)3-401, Su-var(3)401, Su-var(3)4, Suvar(3)4, Su(var)3-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0044475 EP1463 EP1463 http://flybase.org/reports/FBgn0044475 gene - - - EP1463 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0031628 CG3294 - http://flybase.org/reports/FBgn0031628 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 pre-mRNA 3'-splice site binding ; GO:0030628 | inferred from biological aspect of ancestor with PANTHER:PTN000289700 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with protein_id:BAA08533 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000289700 wound healing ; GO:0042060 | inferred from mutant phenotype" spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with protein_id:BAA08533 U2AF ; GO:0089701 | inferred from biological aspect of ancestor with PANTHER:PTN000289700 spliceosomal complex ; GO:0005681 | inferred from biological aspect of ancestor with PANTHER:PTN000289700 "cg3294, CG3294" "IPR000504:RNA recognition motif domain, IPR000571:Zinc finger, CCCH-type, IPR009145:U2 auxiliary factor small subunit" CG3294 11-Aug-17 DroID_v2017_08 "Drer\zrsr2, Drer\u2af1" - Cele\uaf-2 Xtro\u2af1 "Mmus\U2af1l4, Mmus\Zrsr2, Mmus\U2af1, Mmus\Zrsr1" "Hsap\U2AF1L4, Hsap\U2AF1, Hsap\ZRSR2" "viable,fertile" DRSC00590 K -0.116433967 0.155967847 -0.180058277 0.540385362 -3.209488663 0.226632257 FBgn0039288 CG13653 - http://flybase.org/reports/FBgn0039288 protein_coding_gene - - - CG13653 - CG13653 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265724 CR44531 - http://flybase.org/reports/FBgn0265724 non_protein_coding_gene - - - "incRNA.419, CR44531, lincRNA.419" - CR44531 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001005 Fs(2)Vaj Female sterile (2) Vaja http://flybase.org/reports/FBgn0001005 - gene - - - "Vaja, Fs(2)Sz13, Fs(2)Vaj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,dominant" FBgn0016007 l(3)63Fa lethal (3) 63Fa http://flybase.org/reports/FBgn0016007 - gene - - - "l(3)SH8, l(3)63Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020886 Sxl::U2af65 Sxl::U2af65 http://flybase.org/reports/FBgn0020886 - engineered_fusion_gene - - - Sxl::U2af65 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male,viable,female" FBgn0014942 anon-98Dc anon-98Dc http://flybase.org/reports/FBgn0014942 - gene - - - anon-98Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035548 CG15023 - http://flybase.org/reports/FBgn0035548 protein_coding_gene - - - CG15023 - CG15023 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0043021 snRNA:U5:38ABb snRNA:U5:38ABb http://flybase.org/reports/FBgn0043021 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-38ABb, K2, dU5, CR32880, U5snRNA, snRNA:U5, snRNA:U5:38ABb, U5var:38ABb, U5:38ABb, U5 snRNA, U5 38ABb, 38A U5" - CR32880 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053095 CG33095 - http://flybase.org/reports/FBgn0053095 protein_coding_gene - - - "FBgn0039275, CG11938, CG11935, CG33095" - CG33095 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262570 CG43110 - http://flybase.org/reports/FBgn0262570 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "CG43110, MB7.chr2R.pasa.4777" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG43110 11-Aug-17 DroID_v2017_08 "Drer\gzm3, Drer\si:ch211-165b19.9, Drer\si:ch211-165b19.5, Drer\si:dkey-21e2.12, Drer\si:dkey-21e2.7, Drer\si:dkey-21e2.15" - - - "Mmus\Gzmc, Mmus\Klk6, Mmus\Mcpt4, Mmus\Gzmf, Mmus\Cma1, Mmus\Gzmb, Mmus\Gzmd, Mmus\Mcpt9, Mmus\Ctsg, Mmus\Mcpt1, Mmus\Mcpt8, Mmus\Gzmg, Mmus\Gzme, Mmus\Cma2" "Hsap\CTSG, Hsap\GZMB, Hsap\CMA1, Hsap\GZMH" FBgn0069973 CG40485 - http://flybase.org/reports/FBgn0069973 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG40485, FOHSDR" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG40485 11-Aug-17 DroID_v2017_08 "Drer\dhrs11b, Drer\rdh8b, Drer\zgc:92630, Drer\rdh8a, Drer\dhrs11a, Drer\zgc:153724" Scer\YMR226C "Cele\R05D8.7, Cele\F28H7.2, Cele\H04M03.3" "Xtro\dhrs11, Xtro\rdh7, Xtro\rdh8" "Mmus\Rdh8, Mmus\Rdh1, Mmus\Dhrs11" "Hsap\DHRS11, Hsap\RDH8, Hsap\RDH16" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0087016 l(3)61Dd lethal (3) 61Dd http://flybase.org/reports/FBgn0087016 gene - - - l(3)61Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037777 CG11722 - http://flybase.org/reports/FBgn0037777 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from electronic annotation with InterPro:IPR009622 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT14909, CG11722" IPR009622:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 CG11722 11-Aug-17 DroID_v2017_08 Drer\ndufaf4 - Cele\B0035.15 Xtro\ndufaf4 Mmus\Ndufaf4 Hsap\NDUFAF4 "viable,visible" mesothoracic tergum FBgn0261683 B9d2 B9d2 http://flybase.org/reports/FBgn0261683 protein_coding_gene - ciliary transition zone assembly ; GO:1905349 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype ciliary transition zone ; GO:0035869 | inferred from direct assay MKS complex ; GO:0036038 | inferred from sequence or structural similarity with MGI:MGI:2387643 "CG9227, CG42730, B9d2, B9D2" IPR010796:B9 domain CG42730 11-Aug-17 DroID_v2017_08 "Drer\b9d2, Drer\mks1, Drer\b9d1" - "Cele\mksr-2, Cele\mks-1, Cele\mksr-1" "Xtro\mks1, Xtro\b9d1, Xtro\b9d2" "Mmus\Mks1, Mmus\B9d2, Mmus\B9d1" "Hsap\B9D2, Hsap\MKS1" FBgn0267746 CR46077 - http://flybase.org/reports/FBgn0267746 non_protein_coding_gene - - - CR46077 - CR46077 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036709 Or74a Odorant receptor 74a http://flybase.org/reports/FBgn0036709 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "74a, DOR26, 74A.1, CG13726, Or74a" "IPR004117:Olfactory receptor, insect" CG13726 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,viable" FBgn0034269 CG6406 - http://flybase.org/reports/FBgn0034269 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6406 IPR018619:Hyccin CG6406 11-Aug-17 DroID_v2017_08 "Drer\zgc:158316, Drer\fam126a" - Cele\D1069.3 "Xtro\fam126a, Xtro\fam126b" "Mmus\Fam126a, Mmus\Fam126b" "Hsap\FAM126B, Hsap\FAM126A" FBgn0261374 Phox Phenol oxidase http://flybase.org/reports/FBgn0261374 gene catechol oxidase activity ; GO:0004097 | inferred from direct assay monophenol monooxygenase activity ; GO:0004503 | inferred from direct assay - - "Phox, PHOX" - - 11-Aug-17 DroID_v2017_08 - - - - - - "electrophoretic variant,fast,slow,intermediate" FBgn0263849 CG43710 - http://flybase.org/reports/FBgn0263849 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43710 - CG43710 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266940 CR45391 - http://flybase.org/reports/FBgn0266940 pseudogene_attribute - - - CR45391 - CR45391 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267730 CR46061 - http://flybase.org/reports/FBgn0267730 non_protein_coding_gene - - - CR46061 - CR46061 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037798 CG12817 - http://flybase.org/reports/FBgn0037798 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "BcDNA:RE53107, CG12817" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG12817 11-Aug-17 DroID_v2017_08 "Drer\mcfd2, Drer\cgref1" - "Cele\F55A11.1, Cele\T04F3.4, Cele\C29E4.14" "Xtro\mcfd2, Xtro\cgref1" "Mmus\Cgref1, Mmus\Mcfd2" "Hsap\CGREF1, Hsap\MCFD2" viable FBgn0011484 l(3)neo54 lethal (3) neo54 http://flybase.org/reports/FBgn0011484 - gene - - - l(3)neo54 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085757 CR40621 - http://flybase.org/reports/FBgn0085757 rRNA_gene - - - CR40621 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036463 Reck Reversion-inducing-cysteine-rich protein with kazal motifs http://flybase.org/reports/FBgn0036463 protein_coding_gene - - - "RECK, Reck, CG5392" IPR002350:Kazal domain CG5392 11-Aug-17 DroID_v2017_08 "Drer\tmeff2b, Drer\reck, Drer\tmeff1a, Drer\tmeff1b" - - Xtro\reck "Mmus\Spink2, Mmus\Spink13, Mmus\Spink1, Mmus\Spink4, Mmus\Spink7, Mmus\Reck, Mmus\Fstl3, Mmus\Spink6" "Hsap\SPINK7, Hsap\SPINK6, Hsap\FSTL3, Hsap\SPINK1, Hsap\RECK, Hsap\SPINK13, Hsap\SPINK4" FBgn0001889 l(2)21Dc lethal (2) 21Dc http://flybase.org/reports/FBgn0001889 - gene - - - "l(2)neh-3, l(2)neh3, l(2)21Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261702 CR42738 - http://flybase.org/reports/FBgn0261702 non_protein_coding_gene - - - CR42738 - CR42738 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063416 l(3)3450-G lethal (3) 3450-G http://flybase.org/reports/FBgn0063416 gene - - - l(3)3450-G - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0263322 CG43403 - http://flybase.org/reports/FBgn0263322 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43403 - CG43403 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262891 CG43246 - http://flybase.org/reports/FBgn0262891 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43246 - CG43246 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052588 CG32588 - http://flybase.org/reports/FBgn0052588 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs07c08.y1, NEST:bs07c08, BcDNA:AT31812, CG32588" - CG32588 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040522 CG10928 - http://flybase.org/reports/FBgn0040522 protein_coding_gene - - - CG10928 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260564 MENE(3R)-A - http://flybase.org/reports/FBgn0260564 gene - - - "MENE(3R)-A, MENE (3R)-A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye disc,somatic clone" FBgn0066353 l(3)99DEb lethal (3) 99DEb http://flybase.org/reports/FBgn0066353 gene - - - l(3)99DEb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003517 sta stubarista http://flybase.org/reports/FBgn0003517 "FBgn0010239, FBgn0026668, FBgn0029057" protein_coding_gene ribosome binding ; GO:0043022 | inferred from physical interaction with UniProtKB:O76927 structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001865, InterPro:IPR005707, InterPro:IPR018130, InterPro:IPR027498 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000461 | inferred from biological aspect of ancestor with PANTHER:PTN000160708 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000160708 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 rRNA export from nucleus ; GO:0006407 | inferred from biological aspect of ancestor with PANTHER:PTN000160708 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000160708" "small ribosomal subunit ; GO:0015935 | inferred from electronic annotation with InterPro:IPR005707, InterPro:IPR027498 microtubule associated complex ; GO:0005875 | inferred from direct assay 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000160708 ribosome ; GO:0005840 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay" "CG14792, RpSA, Sa, P40, EG:80H7.6, k14, clone 2.56, Rp40, 37LRP/p40, l(1)G0130, l(1)G0448, l(1)2Af, anon-EST:Liang-2.56, Lam-r, sta, STA, Rp 40, Sta, chrX:1339078..1339216" "IPR018130:Ribosomal protein S2, conserved site, IPR001865:Ribosomal protein S2, IPR005707:Ribosomal protein S2, eukaryotic/archaeal, IPR023591:Ribosomal protein S2, flavodoxin-like domain, IPR027498:Ribosomal protein S2, eukaryotic, IPR032281:40S ribosomal protein SA, C-terminal domain" CG14792 11-Aug-17 DroID_v2017_08 "Drer\zgc:110181, Drer\rpsa" "Scer\RPS0A, Scer\RPS0B" Cele\rps-0 Xtro\rpsa Mmus\Rpsa Hsap\RPSA "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,wild-type,visible,viable,female sterile,aging defective,lethal - all die before end of pupal stage,some die during pupal stage" "antenna,macrochaeta,arista,embryonic/larval lymph gland,primary lobe of embryonic/larval lymph gland" DRSC18838 K -1.492578197 -0.9814571 0.763278568 -1.159016268 0.896750291 3.086639783 FBgn0038199 CCHa1 CCHamide-1 http://flybase.org/reports/FBgn0038199 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG14358, CCHa1, Dm-CCHa1, CCM, CCH1, CCHamide-1" - CG14358 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267774 CR46105 - http://flybase.org/reports/FBgn0267774 non_protein_coding_gene - - - CR46105 - CR46105 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011621 l(1)K49h10-5 lethal (1) K49h10-5 http://flybase.org/reports/FBgn0011621 - gene - - - l(1)K49h10-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0043864 pf-2 pairing failure-2 http://flybase.org/reports/FBgn0043864 gene - - - "CG2, pf-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031399 mio missing oocyte http://flybase.org/reports/FBgn0031399 protein_coding_gene - regulation of meiotic nuclear division ; GO:0040020 | inferred from mutant phenotype negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype oocyte fate determination ; GO:0030716 | inferred from mutant phenotype double-strand break repair ; GO:0006302 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype regulation of TORC1 signaling ; GO:1903432 | inferred from mutant phenotype oocyte differentiation ; GO:0009994 | inferred from mutant phenotype positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from physical interaction with Nup44A Seh1-associated complex ; GO:0035859 | inferred from direct assay female germ cell nucleus ; GO:0001674 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay GATOR2 complex ; GO:0061700 | traceable author statement autolysosome ; GO:0044754 | inferred from direct assay Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000000200 "CG15384, CG7074, mio, Mio, SEA4, FBtr0077835, Sea4" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011042:Six-bladed beta-propeller, TolB-like, IPR031488:WD repeat protein mio, zinc-ribbon like domain" CG7074 11-Aug-17 DroID_v2017_08 Drer\mios Scer\SEA4 Cele\F39C12.1 Xtro\mios Mmus\Mios "Hsap\MIOS, Hsap\WDR24" "female sterile,recessive,partially lethal - majority die,some die during pupal stage" "nurse cell,egg chamber,oocyte,centriole,microtubule,oocyte & germarium,synaptonemal complex & presumptive oocyte & germarium region 2a,presumptive oocyte & pachytene,presumptive oocyte & zygotene" FBgn0039619 CG14519 - http://flybase.org/reports/FBgn0039619 protein_coding_gene - - - CG14519 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0022173 l(2)k05421 lethal (2) k05421 http://flybase.net/reports/FBgn0022173.html gene l(2)k05433 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0032751 CG17343 - http://flybase.org/reports/FBgn0032751 protein_coding_gene - - - "CG17343, Cdc26" - CG17343 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0050080 CG30080 - http://flybase.org/reports/FBgn0050080 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12965, BcDNA:RE70859, BcDNA:RE42467, CG30080" - CG30080 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" DRSC05571 IK 0.734612714 1.501406068 0.168046301 0.117828075 0.703203324 2.191254959 FBgn0060434 l(3)S125310b lethal (3) S125310b http://flybase.org/reports/FBgn0060434 gene - - - "1253/10, l(3)S125310b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085207 CG34178 - http://flybase.org/reports/FBgn0085207 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34178 IPR029277:Single domain Von Willebrand factor type C domain CG34178 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052363 tRNA:Leu-CAG-1-7 transfer RNA:Leucine-CAG 1-7 http://flybase.org/reports/FBgn0052363 tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "CR32363, AE002602.trna5-LeuCAG, tRNA[Leu][[2]], tRNA:leu2:66B, tRNA:L2:66B, tRNA:L:CAG:AE002602-a, chr3L.trna39-LeuCAG, tRNA-Leu-CAG-1-7, tRNA:Leu-CAG-1-7, tRNA:CR32363, CUG" - CR32363 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044107 E(rst)C389 E(rst)C389 http://flybase.org/reports/FBgn0044107 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C389, E(rst)C389" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0034512 CG18067 - http://flybase.org/reports/FBgn0034512 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CT40493, CG18067" IPR008972:Cupredoxin CG18067 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0086610 CG33342 HDC15381 http://flybase.org/reports/FBgn0086610 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG33342, BP1089, HDC15381, mdcds_42691" IPR006631:Protein of unknown function DM4/12 CG33342 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263852 Dad1 Defender against apoptotic cell death 1 http://flybase.org/reports/FBgn0263852 protein_coding_gene dolichyl-diphosphooligosaccharide-protein glycotransferase activity ; GO:0004579 | inferred from electronic annotation with InterPro:IPR003038 oligosaccharyl transferase activity ; GO:0004576 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000076010 protein N-linked glycosylation ; GO:0006487 | inferred from biological aspect of ancestor with PANTHER:PTN000076010 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR003038 oligosaccharyltransferase complex ; GO:0008250 | inferred from biological aspect of ancestor with PANTHER:PTN000076010 endomembrane system ; GO:0012505 | inferred from direct assay "CG13393, BcDNA:RE23864, Dad1, dDad1, l(2)k12914, OST" IPR003038:DAD/Ost2 CG13393 11-Aug-17 DroID_v2017_08 Drer\dad1 Scer\OST2 Cele\dad-1 Xtro\dad1 Mmus\Dad1 Hsap\DAD1 FBgn0261861 CR42790 - http://flybase.org/reports/FBgn0261861 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lincRNA.863, CG42790, CR42790" - CR42790 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265348 CR44302 - http://flybase.org/reports/FBgn0265348 non_protein_coding_gene - - - CR44302 - CR44302 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265592 CR44419 - http://flybase.org/reports/FBgn0265592 non_protein_coding_gene - - - CR44419 - CR44419 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266526 CG45093 - http://flybase.org/reports/FBgn0266526 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45093 - CG45093 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262449 mir-2b-2 mir-2b-2 stem loop http://flybase.org/reports/FBgn0262449 miRNA_gene - negative regulation of translational initiation ; GO:0045947 | inferred from direct assay negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "mir-2b-2, mir-2b, 2b-2, miR-2, dme-mir-2b-2, 2b-1/2, MIR-2, CR43016, miR-2b, miR-2b-2, miR2b, CR32964, miR2, dme-miR-2b, dme-miR-2b-2" - CR43016 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage "visible,lethal" wing FBgn0267086 CR45530 - http://flybase.org/reports/FBgn0267086 non_protein_coding_gene - - - CR45530 - CR45530 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035736 Cpr65Eb Cuticular protein 65Eb http://flybase.org/reports/FBgn0035736 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:RE28679, Cpr65Eb, CG8638, DmelCpr65Eb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8638 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\H2-K1, Mmus\2410137M14Rik" - "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0014317 l(3)ry125b lethal (3) ry125b http://flybase.org/reports/FBgn0014317 - gene - - - l(3)ry125b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003581 Su(ss) Suppressor of spineless http://flybase.org/reports/FBgn0003581 - gene - - - Su(ss) - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "posterior scutellar bristle,macrochaeta" FBgn0011663 mrr myosin rod-related http://flybase.org/reports/FBgn0011663 - gene - - - mrr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031533 CG2772 - http://flybase.org/reports/FBgn0031533 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - "BcDNA:RE45077, CG2772" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG2772 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH1, Scer\TGL1, Scer\YEH2" "Cele\lipl-7, Cele\lipl-8, Cele\lipl-2, Cele\lipl-3, Cele\lipl-5, Cele\lipl-1, Cele\lipl-4, Cele\lipl-6" Xtro\lipa "Mmus\Lipo3, Mmus\Lipk, Mmus\Lipo2, Mmus\Lipf, Mmus\Lipm, Mmus\Lipn, Mmus\Lipa, Mmus\Lipo1, Mmus\Lipo4" "Hsap\LIPK, Hsap\LIPM, Hsap\LIPA, Hsap\LIPN, Hsap\LIPF, Hsap\LIPJ" viable FBgn0039807 CG15546 - http://flybase.org/reports/FBgn0039807 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15546 - CG15546 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267282 CR45718 - http://flybase.org/reports/FBgn0267282 non_protein_coding_gene - - - CR45718 - CR45718 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052484 Sk2 Sphingosine kinase 2 http://flybase.org/reports/FBgn0052484 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 D-erythro-sphingosine kinase activity ; GO:0017050 | inferred from direct assay diacylglycerol kinase activity ; GO:0004143 | non-traceable author statement sphingolipid metabolic process ; GO:0006665 | inferred from direct assay flight behavior ; GO:0007629 | inferred from mutant phenotype oviposition ; GO:0018991 | inferred from mutant phenotype phosphorylation ; GO:0016310 | non-traceable author statement phosphorylation ; GO:0016310 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from direct assay "CG32484, CG2159, Sphk2, SK2, Sk2, sk2" "IPR001206:Diacylglycerol kinase, catalytic domain, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG32484 11-Aug-17 DroID_v2017_08 "Drer\sphk1, Drer\sphk2, Drer\cerk, Drer\zgc:158263" "Scer\LCB4, Scer\TIM54, Scer\LCB5" "Cele\F52C9.3, Cele\sphk-1, Cele\T10B11.2" "Xtro\sphk1, Xtro\cerkl, Xtro\sphk2" "Mmus\Cerk, Mmus\Sphk2, Mmus\Sphk1" "Hsap\CERK, Hsap\CERKL, Hsap\SPHK1, Hsap\SPHK2" "viable,female sterile,recessive,flight defective,fertile" "eye,photoreceptor cell,ommatidium,rhabdomereGMR.PF,heat sensitive,rhabdomere | heat sensitiveGMR.PF, GAL80ts.‘±Tub84B" FBgn0266729 CR45202 - http://flybase.org/reports/FBgn0266729 non_protein_coding_gene - - - CR45202 - CR45202 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032847 Taf13 TBP-associated factor 13 http://flybase.org/reports/FBgn0032847 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from sequence or structural similarity with HGNC:11546 inferred from sequence or structural similarity with SGD:S000004564" transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11546 transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11546 inferred from sequence or structural similarity with SGD:S000004564 "dTAF[[II]]18, TAF, TFIID, TAF[[II]], TAF[[II]]18, TAF13, 38B.15, CG10756, TAF18, Taf18, Taf13" "IPR003195:Transcription initiation factor IID, subunit 13, IPR009072:Histone-fold" CG10756 11-Aug-17 DroID_v2017_08 Drer\taf13 "Scer\TAF13, Scer\SPT3" Cele\taf-13 Xtro\taf13 "Mmus\Supt3, Mmus\Taf13" "Hsap\TAF13, Hsap\SUPT3H" "viable,visible" "chaeta,supernumerary" FBgn0052545 CG32545 - http://flybase.org/reports/FBgn0052545 protein_coding_gene - - - CG32545 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023221 E(lz)15 E(lz)15 http://flybase.org/reports/FBgn0023221 - gene - - - E(lz)15 - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0065827 l(2)SH0357 lethal (2) SH0357 http://flybase.org/reports/FBgn0065827 gene - - - "l(2)SH0357, l(2)SH2 0357" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084271 l(3)AS69 lethal (3) AS69 http://flybase.org/reports/FBgn0084271 gene - - - l(3)AS69 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031277 CG13947 - http://flybase.org/reports/FBgn0031277 protein_coding_gene - - - CG13947 - CG13947 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060344 l(3)S143609 lethal (3) S143609 http://flybase.org/reports/FBgn0060344 gene - - - "1436/09, l(3)S143609" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0021992 l(2)k09610 lethal (2) k09610 http://flybase.net/reports/FBgn0021992.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0003614 Su(var)2-12 Suppressor of variegation 2-12 http://flybase.org/reports/FBgn0003614 - gene - - - "Su-var(2)12, Su(var)2-12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0039225 Ets96B Ets96B http://flybase.org/reports/FBgn0039225 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000218930" "positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 response to starvation ; GO:0042594 | inferred from mutant phenotype regulation of dopamine receptor signaling pathway ; GO:0060159 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000218930" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 "Ets, CG6892, Ets96B, ets96B" "IPR000418:Ets domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG6892 11-Aug-17 DroID_v2017_08 "Drer\elk3, Drer\gabpa, Drer\elk1, Drer\ets2, Drer\erf, Drer\etv2, Drer\etv5b, Drer\erg, Drer\elk4, Drer\etv1, Drer\fli1a, Drer\fli1b, Drer\etv4, Drer\LOC100537796, Drer\fev, Drer\erfl3, Drer\etv5a" - "Cele\ets-9, Cele\ets-8" "Xtro\elk3, Xtro\ets2, Xtro\ets1, Xtro\etv2, Xtro\erg, Xtro\elk4, Xtro\gabpa, Xtro\etv1, Xtro\etv3, Xtro\elk1, Xtro\erf" "Mmus\Etv3, Mmus\Ets2, Mmus\Etv5, Mmus\Etv4, Mmus\Elk4, Mmus\Erg, Mmus\Erf, Mmus\Fli1, Mmus\Ets1, Mmus\Gabpa, Mmus\Fev, Mmus\Elk1, Mmus\Etv2, Mmus\Elk3, Mmus\Etv1" "Hsap\ETV5, Hsap\ETV1, Hsap\ELK3, Hsap\ETS2, Hsap\ERG, Hsap\ETS1, Hsap\ELK1, Hsap\ETV4, Hsap\ERF, Hsap\FEV, Hsap\GABPA, Hsap\ETV2, Hsap\FLI1, Hsap\ETV3, Hsap\ETV3L, Hsap\ELK4" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16127 IK 1.561532078 -0.398148557 -0.083853677 -0.00114459 1.684860398 0.798561845 FBgn0262100 CG42853 - http://flybase.org/reports/FBgn0262100 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42853 IPR003388:Reticulon CG42853 11-Aug-17 DroID_v2017_08 "Drer\rtn2a, Drer\rtn4a, Drer\rtn4b, Drer\rtn2b, Drer\rtn1b, Drer\rtn3, Drer\rtn1a" "Scer\RTN1, Scer\RTN2" Cele\ret-1 "Xtro\rtn4, Xtro\rtn2, Xtro\rtn1, Xtro\rtn3" "Mmus\Rtn2, Mmus\Rtn4, Mmus\Rtn1, Mmus\Rtn3" "Hsap\RTN4, Hsap\RTN3, Hsap\RTN1, Hsap\RTN2" FBgn0044004 Su(rst)C195 Su(rst)C195 http://flybase.org/reports/FBgn0044004 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C195, Su(rst)C195" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0266685 CR45175 - http://flybase.org/reports/FBgn0266685 non_protein_coding_gene - - - CR45175 - CR45175 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061403 CG32738 - http://flybase.org/reports/FBgn0061403 protein_coding_gene - - - "BcDNA:RE36972, CG32738" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004985 bow bow wings http://flybase.org/reports/FBgn0004985 - gene - - - bow - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0045036 stuk stuk http://flybase.org/reports/FBgn0045036 gene - - - stuk - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005779 PpD6 Protein phosphatase D6 http://flybase.org/reports/FBgn0005779 FBgn0031503 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006186 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity" protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity protein dephosphorylation ; GO:0006470 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CG8822, D6, PpD6, PP1" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like, IPR031675:Serine-threonine protein phosphatase, N-terminal" CG8822 11-Aug-17 DroID_v2017_08 "Drer\ppp1caa, Drer\ppp1cab, Drer\ppp1cbl, Drer\ppp1cc" "Scer\GLC7, Scer\PPQ1, Scer\PPZ1, Scer\PPZ2" "Cele\Y71G12B.30, Cele\F20D6.6, Cele\F22D6.9, Cele\F52H3.6, Cele\F23B12.1, Cele\pph-1, Cele\T25B9.2, Cele\ZK938.1, Cele\R13A5.11, Cele\C30A5.4, Cele\gsp-2, Cele\C34D4.2, Cele\Y69E1A.4" "Xtro\ppp1cb, Xtro\ppp1ca" "Mmus\Ppp1ca, Mmus\Ppp1cc" "Hsap\PPP1CA, Hsap\PPP1CC" "viable,fertile,lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0036789 AstC-R2 Allatostatin C receptor 2 http://flybase.org/reports/FBgn0036789 protein_coding_gene somatostatin receptor activity ; GO:0004994 | inferred from electronic annotation with InterPro:IPR000586 allatostatin receptor activity ; GO:0008261 | inferred from direct assay neuropeptide binding ; GO:0042923 | inferred from biological aspect of ancestor with PANTHER:PTN000659780 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger ; GO:0007187 | inferred from biological aspect of ancestor with PANTHER:PTN001200938 neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity" integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN001200938 integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0008261 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG13702, Drostar2, anon-WO0170980.155, anon-WO0170980.154, AlCR2, ASTC-R2, AlCR-2, AstC-R2, lincRNA.610, Aicr2" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000586:Somatostatin receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG13702 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-160i9.3, Drer\hcar1-1, Drer\LOC100535160, Drer\sstr1a, Drer\LOC571123, Drer\c5ar1, Drer\sstr5, Drer\oprl1, Drer\sstr3, Drer\si:dkey-148a17.5, Drer\sstr2a, Drer\gpr1, Drer\p2ry12, Drer\cxcr2, Drer\bdkrb1, Drer\sstr2b, Drer\si:dkey-42l23.4, Drer\gpr17, Drer\gpr174, Drer\gpr183a, Drer\cxcr3.2, Drer\ccr12a, Drer\p2ry10, Drer\si:dkey-165n16.5, Drer\p2ry2.2, Drer\f2rl1.1, Drer\gpr34a, Drer\oprd1a, Drer\LOC100005512, Drer\oprd1b, Drer\si:dkey-96n2.3, Drer\ptafr, Drer\p2ry2.1, Drer\si:zfos-169g10.2, Drer\gpr34b, Drer\LOC556451, Drer\zgc:194202, Drer\ccr6b, Drer\p2ry4, Drer\si:ch211-184m13.4, Drer\cysltr1, Drer\xcr1a.1, Drer\mchr1a, Drer\p2ry1, Drer\ccr9a, Drer\fpr1, Drer\LOC564730, Drer\LOC101883086, Drer\mchr1b, Drer\si:dkey-211g8.1, Drer\si:dkey-42l23.2, Drer\p2ry2.3, Drer\gpr183b, Drer\cysltr2a, Drer\LOC793479, Drer\LOC100333697, Drer\LOC799203, Drer\LOC100334739, Drer\gpr34l, Drer\gpr171, Drer\oprk1, Drer\gpr4, Drer\oprm1, Drer\sstr1b, Drer\LOC558520, Drer\ackr3a, Drer\cmklr1, Drer\hcar1-2" - "Cele\npr-16, Cele\npr-30, Cele\npr-24, Cele\F16C3.1, Cele\npr-18, Cele\F36D4.4" "Xtro\npbwr1, Xtro\oprk1, Xtro\p2ry13, Xtro\p2ry12, Xtro\cysltr1, Xtro\gpr25, Xtro\lpar5, Xtro\sstr5, Xtro\c5ar1, Xtro\LOC100487226, Xtro\sstr4, Xtro\sstr2, Xtro\cxcr4, Xtro\cmklr1, Xtro\mchr1.1, Xtro\p2ry1, Xtro\c3ar1, Xtro\cxcr5, Xtro\ptafr, Xtro\LOC100497020, Xtro\ccr7, Xtro\sstr3, Xtro\p2ry4, Xtro\lpar4, Xtro\oprm1, Xtro\f2rl3, Xtro\cxcr3, Xtro\p2ry14" "Mmus\Sstr5, Mmus\Gpr1, Mmus\Ccr1, Mmus\Ccr10, Mmus\C3ar1, Mmus\Ptgdr2, Mmus\Fpr-rs4, Mmus\Lpar6, Mmus\Sstr4, Mmus\Sstr1, Mmus\Ltb4r2, Mmus\Bdkrb2, Mmus\Cxcr2, Mmus\Mchr1, Mmus\Ltb4r1, Mmus\Gpr87, Mmus\Cmklr1, Mmus\Cysltr2, Mmus\Ackr3, Mmus\Fpr-rs6, Mmus\Oprm1, Mmus\Gpr17, Mmus\Sstr2, Mmus\Npbwr1, Mmus\P2ry12, Mmus\Gpr34, Mmus\Ptafr, Mmus\Ackr2, Mmus\Gpr171, Mmus\Gpr183, Mmus\P2ry4, Mmus\Rxfp4, Mmus\Cxcr1, Mmus\Fpr2, Mmus\Gpr33, Mmus\Fpr-rs3, Mmus\Oprd1, Mmus\Cysltr1, Mmus\C5ar1, Mmus\Fpr1, Mmus\Gpr149, Mmus\F2rl3, Mmus\C5ar2, Mmus\P2ry1, Mmus\P2ry13, Mmus\Oprl1, Mmus\Fpr3, Mmus\Gpr82, Mmus\Sstr3, Mmus\Cxcr3, Mmus\P2ry14, Mmus\Oprk1, Mmus\Cx3cr1" "Hsap\SSTR1, Hsap\GPR33, Hsap\ACKR4, Hsap\OPRD1, Hsap\CYSLTR2, Hsap\OPRM1, Hsap\SSTR2, Hsap\SSTR4, Hsap\MCHR2, Hsap\GPR34, Hsap\C3AR1, Hsap\SSTR5, Hsap\GPR183, Hsap\GPR17, Hsap\HCAR3, Hsap\OPRPN, Hsap\C5AR2, Hsap\GPR32, Hsap\P2RY13, Hsap\PTGDR2, Hsap\NPBWR1, Hsap\CYSLTR1, Hsap\XCR1, Hsap\P2RY12, Hsap\F2R, Hsap\GPR171, Hsap\LPAR6, Hsap\CCR9, Hsap\PTAFR, Hsap\P2RY1, Hsap\CXCR1, Hsap\CXCR3, Hsap\P2RY14, Hsap\CX3CR1, Hsap\CCRL2, Hsap\OPRK1, Hsap\RXFP4, Hsap\FPR2, Hsap\FPR3, Hsap\ACKR2, Hsap\NPBWR2, Hsap\SSTR3, Hsap\FPR1, Hsap\BDKRB2, Hsap\CXCR2, Hsap\LTB4R2, Hsap\OPRL1, Hsap\GPR87, Hsap\GPR1, Hsap\P2RY4, Hsap\MCHR1, Hsap\GPR149" " adult stage , larval stage " " lamina & glial cell

, pars intercerebralis | restricted

, larval central nervous system | restricted

, monopolar laminar cell

" "viable,fertile" FBgn0010222 Nmdmc NAD-dependent methylenetetrahydrofolate dehydrogenase http://flybase.org/reports/FBgn0010222 FBgn0037658 protein_coding_gene methenyltetrahydrofolate cyclohydrolase activity ; GO:0004477 | inferred from sequence or structural similarity methenyltetrahydrofolate cyclohydrolase activity ; GO:0004477 | inferred from sequence or structural similarity with UniProtKB:P09440 methenyltetrahydrofolate cyclohydrolase activity ; GO:0004477 | inferred from biological aspect of ancestor with PANTHER:PTN000002250 magnesium ion binding ; GO:0000287 | inferred from sequence or structural similarity with UniProtKB:P13995 methylenetetrahydrofolate dehydrogenase (NAD+) activity ; GO:0004487 | inferred from biological aspect of ancestor with PANTHER:PTN000002329 methylenetetrahydrofolate dehydrogenase (NAD+) activity ; GO:0004487 | inferred from sequence or structural similarity with UniProtKB:P13995 methylenetetrahydrofolate dehydrogenase (NADP+) activity ; GO:0004488 | inferred from biological aspect of ancestor with PANTHER:PTN000002250 methenyltetrahydrofolate cyclohydrolase activity ; GO:0004477 | inferred from sequence or structural similarity with UniProtKB:P13995 methylenetetrahydrofolate dehydrogenase (NADP+) activity ; GO:0004488 | inferred from sequence or structural similarity with UniProtKB:P13995 phosphate ion binding ; GO:0042301 | inferred from sequence or structural similarity with UniProtKB:P13995 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000672, InterPro:IPR020630, InterPro:IPR020631, InterPro:IPR020867 folic acid-containing compound biosynthetic process ; GO:0009396 | inferred from electronic annotation with InterPro:IPR000672, InterPro:IPR020630, InterPro:IPR020631, InterPro:IPR020867 one-carbon metabolic process ; GO:0006730 | inferred from biological aspect of ancestor with PANTHER:PTN000002250 carbohydrate metabolic process ; GO:0005975 | inferred from sequence or structural similarity with UniProtKB:P13995 tetrahydrofolate metabolic process ; GO:0046653 | inferred from sequence or structural similarity with UniProtKB:P13995 10-formyltetrahydrofolate metabolic process ; GO:0009256 | inferred from sequence or structural similarity with UniProtKB:P13995" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P09440 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000002329 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P13995 "151767_at, CG18466, DNMDMC, dNMDMC, Dnmdmc, Nmdmc, nmdmc, Mthfd2" "IPR000672:Tetrahydrofolate dehydrogenase/cyclohydrolase, IPR016040:NAD(P)-binding domain, IPR020630:Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, IPR020631:Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, IPR020867:Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site" CG18466 11-Aug-17 DroID_v2017_08 "Drer\mthfd2, Drer\mthfd1l, Drer\mthfd1b, Drer\mthfd1a, Drer\grhprb, Drer\mthfd2l, Drer\zgc:136493, Drer\grhpra" "Scer\MTD1, Scer\ADE3, Scer\MIS1" "Cele\dao-3, Cele\K07E3.4" "Xtro\grhpr.2, Xtro\mthfd2, Xtro\mthfd2l, Xtro\grhpr.1" "Mmus\Grhpr, Mmus\Mthfd2, Mmus\Mthfd1, Mmus\Mthfd1l, Mmus\Mthfd2l" "Hsap\MTHFD2, Hsap\MTHFD2L, Hsap\MTHFD1, Hsap\MTHFD1L" embryonic stage -- adult stage "viable,fertile" FBgn0263206 CG43376 - http://flybase.org/reports/FBgn0263206 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43376 - CG43376 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023105 anon-23Aa anon-23Aa http://flybase.org/reports/FBgn0023105 - gene - - - anon-23Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266630 CR45137 - http://flybase.org/reports/FBgn0266630 non_protein_coding_gene - - - CR45137 - CR45137 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010166 pseudoscute pseudoscute http://flybase.org/reports/FBgn0010166 - gene - - - "pseudoscute, psc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022192 l(2)k05104 lethal (2) k05104 http://flybase.org/reports/FBgn0022192 - gene - - - l(2)k05104 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262616 CR43142 - http://flybase.org/reports/FBgn0262616 pseudogene_attribute - - - CR43142 - CR43142 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028110 l(3)S068609 lethal (3) S068609 http://flybase.org/reports/FBgn0028110 gene - - - l(3)S068609 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034232 CG4866 - http://flybase.org/reports/FBgn0034232 protein_coding_gene rRNA binding ; GO:0019843 | inferred from electronic annotation with InterPro:IPR001912 snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000216482 cellular response to starvation ; GO:0009267 | inferred from expression pattern rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000216482 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000216482 Mpp10 complex ; GO:0034457 | inferred from biological aspect of ancestor with PANTHER:PTN000216482 "mRpS4, CG4866" "IPR002942:RNA-binding S4 domain, IPR001912:Ribosomal protein S4/S9, N-terminal, IPR022801:Ribosomal protein S4/S9" CG4866 11-Aug-17 DroID_v2017_08 Drer\imp3 Scer\IMP3 Cele\C48B6.2 Xtro\imp3 Mmus\Imp3 Hsap\IMP3 "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0028689 Rpn6 Regulatory particle non-ATPase 6 http://flybase.org/reports/FBgn0028689 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from biological aspect of ancestor with PANTHER:PTN000073599 protein binding ; GO:0005515 | inferred from physical interaction with Rpn7 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000073599 proteasome assembly ; GO:0043248 | inferred from biological aspect of ancestor with PANTHER:PTN000073599 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 "proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000002255 proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9556 inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000073599 microtubule associated complex ; GO:0005875 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay" "p42B, CG10149, l(2)k00103, BcDNA.LD18931, Pros44.5, BcDNA:LD18931, Rpn6, rpn6, S9, CG5289, dPSMD11" "IPR000717:Proteasome component (PCI) domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain" CG10149 11-Aug-17 DroID_v2017_08 "Drer\psmd11a, Drer\psmd11b" Scer\RPN6 "Cele\rpn-6.1, Cele\rpn-6.2" Xtro\psmd11 Mmus\Psmd11 Hsap\PSMD11 "lethal,recessive,neuroanatomy defective,somatic clone,decreased cell number,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,cell lethalcell lethal" "mushroom body gamma-lobe,somatic clone,neuroblast,adult mushroom body" DRSC07541 IEK -2.917126882 -2.849851167 -1.833524703 -3.83491377 -1.036150642 -2.002357269 FBgn0005260 l(3)SG80 lethal (3) SG80 http://flybase.org/reports/FBgn0005260 - gene - - - l(3)SG80 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267500 2SrRNA:CR45840 2S ribosomal RNA:CR45840 http://flybase.org/reports/FBgn0267500 rRNA_gene - - - "2SrRNA:CR45840, CR45840" - CR45840 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002417 l(3)DTS4 lethal (3) DTS4 http://flybase.org/reports/FBgn0002417 - gene - - - "DTS-4, l(3)DTS4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive" FBgn0260224 CG42498 - http://flybase.org/reports/FBgn0260224 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42498, Dromel_CG14550_FBtr0084974_uORF, Dm pcc1" IPR015419:CTAG/Pcc1 family CG42498 11-Aug-17 DroID_v2017_08 "Drer\pigp, Drer\lage3" Scer\PCC1 Cele\F59A2.5 Xtro\pigp "Mmus\Gm6880, Mmus\Lage3, Mmus\Ctag2, Mmus\Gm6890, Mmus\Pigp" "Hsap\LAGE3, Hsap\CTAG2, Hsap\CTAG1A, Hsap\CTAG1B" FBgn0262772 Su(E1)-F - http://flybase.org/reports/FBgn0262772 gene - - - Su(E1)-F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004856 Bx42 Bx42 http://flybase.org/reports/FBgn0004856 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with asf1 transcription cofactor activity ; GO:0003712 | inferred from biological aspect of ancestor with PANTHER:PTN002281016 "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN002281016 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype generation of catalytic spliceosome for second transesterification step ; GO:0000350 | inferred from biological aspect of ancestor with PANTHER:PTN002281016" Prp19 complex ; GO:0000974 | inferred from direct assay post-mRNA release spliceosomal complex ; GO:0071014 | inferred from biological aspect of ancestor with PANTHER:PTN002281016 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay SMAD protein complex ; GO:0071141 | inferred from biological aspect of ancestor with PANTHER:PTN002281016 nuclear chromatin ; GO:0000790 | colocalizes_with non-traceable author statement "CG8264, Bx42, Skip, SKIP, BX42, bx42" "IPR004015:SKI-interacting protein SKIP, SNW domain, IPR017862:SKI-interacting protein, SKIP" CG8264 11-Aug-17 DroID_v2017_08 "Drer\tbc1d22b, Drer\tbc1d22a, Drer\snw1" Scer\PRP45 Cele\skp-1 "Xtro\tbc1d22b, Xtro\tbc1d22a, Xtro\snw1" "Mmus\Tbc1d22b, Mmus\Snw1, Mmus\Tbc1d22a" "Hsap\TBC1D22B, Hsap\TBC1D22A, Hsap\SNW1" embryonic stage

ubiquitous " larval stage | third instar , adult stage && oogenesis stage , embryonic stage | cellular blastoderm , embryonic stage " " larval salivary gland

, follicle cell

, nurse cell

" "viable,fertile,neuroanatomy defective,lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,salivary gland,eye,antenna,ectopic,head | P-stage,gnathal segment,mouthpart,anterior scutellar bristle,posterior scutellar bristle,anterior crossvein,wing vein L3,leg,1st posterior cell,wing vein" DRSC17743 EK -1.15987685 -0.345352015 -3.921648019 -4.411487858 -3.03720369 -0.587458187 FBgn0033286 CG2127 - http://flybase.org/reports/FBgn0033286 protein_coding_gene - - - "CG2127, bs19a07.y1, NEST:bs19a07, anon-WO0140519.25" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG2127 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0039424 ppk15 pickpocket 15 http://flybase.org/reports/FBgn0039424 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG14239, ppk15" IPR001873:Epithelial sodium channel CG14239 11-Aug-17 DroID_v2017_08 "Drer\asic1a, Drer\asic4b, Drer\asic1b, Drer\asic2, Drer\asic4a, Drer\asic1c" - "Cele\del-7, Cele\delm-1, Cele\acd-4, Cele\acd-2, Cele\delm-2, Cele\acd-1, Cele\acd-3, Cele\acd-5, Cele\flr-1" "Xtro\scnn1a, Xtro\asic4, Xtro\asic5, Xtro\scnn1b, Xtro\scnn1g, Xtro\asic1, Xtro\scnn1d" "Mmus\Asic4, Mmus\Scnn1b, Mmus\Asic2, Mmus\Scnn1g, Mmus\Asic5, Mmus\Asic1, Mmus\Asic3, Mmus\Scnn1a" "Hsap\ASIC5, Hsap\ASIC2, Hsap\ASIC1, Hsap\SCNN1D, Hsap\SCNN1B, Hsap\SCNN1G, Hsap\ASIC3, Hsap\SCNN1A, Hsap\ASIC4" viable FBgn0032512 CG9305 - http://flybase.org/reports/FBgn0032512 protein_coding_gene TFIIIB-type transcription factor activity ; GO:0001026 | inferred from electronic annotation with InterPro:IPR030701 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 TFIIIC-class transcription factor binding ; GO:0001156 | inferred from biological aspect of ancestor with PANTHER:PTN000532088 RNA polymerase III transcriptional preinitiation complex assembly ; GO:0070898 | inferred from biological aspect of ancestor with PANTHER:PTN000532088 neurogenesis ; GO:0022008 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype transcription factor TFIIIB complex ; GO:0000126 | inferred from biological aspect of ancestor with PANTHER:PTN000532088 "CG9305, Bdp1" "IPR001005:SANT/Myb domain, IPR009057:Homeobox domain-like, IPR030701:Transcription factor TFIIIB component B''" CG9305 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-204c21.1, Drer\zgc:162472" Scer\BDP1 Cele\B0261.1 - Mmus\Bdp1 Hsap\BDP1 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC03192 K 0.398334979 -0.678673429 0.589984839 -0.972481727 -1.701147062 -0.974367294 FBgn0011738 wwy wrong way http://flybase.org/reports/FBgn0011738 - gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available wwy - - 11-Aug-17 DroID_v2017_08 - - - - - - "chordotonal organ & axon | lateral,commissure,longitudinal connective" FBgn0039702 Vps16B Vacuolar protein sorting 16B http://flybase.org/reports/FBgn0039702 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Vps33B intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR006925 phagosome-lysosome fusion ; GO:0090385 | inferred from mutant phenotype regulation of SNARE complex assembly ; GO:0035542 | inferred from sequence or structural similarity with SGD:S000005966 phagosome maturation ; GO:0090382 | inferred from direct assay endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000005966 immune response ; GO:0006955 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9H9C1 CORVET complex ; GO:0033263 | inferred from sequence or structural similarity with SGD:S000005966 HOPS complex ; GO:0030897 | inferred from direct assay HOPS complex ; GO:0030897 | inferred from sequence or structural similarity with SGD:S000005966 "CG18112, Vps16B, dVps16B, fob, Vps16b" "IPR006925:Vps16, C-terminal" CG18112 11-Aug-17 DroID_v2017_08 "Drer\vipas39, Drer\golga5" - Cele\spe-39 "Xtro\golga5, Xtro\vipas39" "Mmus\Golga5, Mmus\Vipas39" "Hsap\GOLGA5, Hsap\VIPAS39" "visible,partially lethal - majority die,some die during pupal stage,viable,fertile,immune response defective" "trichogen cell,hemocyte" FBgn0000696 fltB flight defective B http://flybase.org/reports/FBgn0000696 - gene - - - fltB - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0017484 Su(var)324 Suppressor of variegation 324 http://flybase.org/reports/FBgn0017484 - gene - - - Su(var)324 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant" FBgn0261863 lnr lingerer on 2L http://flybase.org/reports/FBgn0261863 gene - larval foraging behavior ; GO:0035177 | inferred from mutant phenotype - lnr - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263567 mir-4915 mir-4915 stem loop http://flybase.org/reports/FBgn0263567 miRNA_gene - - - "mir-4915, dme-mir-4915, CR43552" - CR43552 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010282 TfIIFalpha Transcription factor IIFalpha http://flybase.org/reports/FBgn0010282 FBgn0010281 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR008851 catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011039 TFIIF-class transcription factor binding ; GO:0001096 | inferred from physical interaction with TfIIFβ neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4652 inferred from sequence or structural similarity with SGD:S000003418 positive regulation of transcription initiation from RNA polymerase II promoter ; GO:0060261 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay transcription factor TFIIF complex ; GO:0005674 | inferred from sequence or structural similarity with HGNC:4652 inferred from sequence or structural similarity with SGD:S000003418 transcription factor TFIIF complex ; GO:0005674 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "154355_at, CG10281, TFIIF, TFIIF-L, TFIIFalpha, F5a, TfIIF, TfIIFalpha, TFIIFa, DmTFIIF" "IPR011039:Transcription Factor IIF, Rap30/Rap74, interaction, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR008851:Transcription initiation factor IIF, alpha subunit" CG10281 11-Aug-17 DroID_v2017_08 Drer\gtf2f1 Scer\TFG1 Cele\C01F1.1 Xtro\gtf2f1 Mmus\Gtf2f1 Hsap\GTF2F1 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC12608 IK 0.717110214 3.410797271 -0.905632142 0.80246442 1.579373929 0.604596943 FBgn0259637 B0625 - http://flybase.org/reports/FBgn0259637 gene - - - B0625 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein L3 FBgn0265491 BG01478 - http://flybase.org/reports/FBgn0265491 gene - - - BG01478 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263514 mir-4966-1 mir-4966-1 stem loop http://flybase.org/reports/FBgn0263514 miRNA_gene - - - "CR43499, dme-mir-4966, chou39-1, mir-4966-1, dme-mir-4966-1, mir-4966" - CR43499 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040183 l(1)G0257 lethal (1) G0257 http://flybase.org/reports/FBgn0040183 gene - - - l(1)G0257 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039591 CG9988 - http://flybase.org/reports/FBgn0039591 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG9988, gi23172514" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG9988 11-Aug-17 DroID_v2017_08 - - "Cele\M03F8.5, Cele\T07G12.3, Cele\F07C3.3, Cele\R03G8.1, Cele\T23E1.1, Cele\F10C2.3, Cele\Y38A10A.2, Cele\F32D8.2, Cele\K03A11.4, Cele\R03G8.3, Cele\Y41E3.1, Cele\F15H10.7, Cele\Y73F8A.35, Cele\F32G8.2" - - - viable FBgn0065213 l(2)SH2258 lethal (2) SH2258 http://flybase.org/reports/FBgn0065213 gene - - - "l(2)SH2258, l(2)SH2 2258" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004496 fs(1)201 female sterile (1) 201 http://flybase.org/reports/FBgn0004496 - gene - - - fs(1)201 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004432 Cyp1 Cyclophilin 1 http://flybase.org/reports/FBgn0004432 FBgn0047257 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from sequence or structural similarity" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern" cytosol ; GO:0005829 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "Cpy1, cyp-1, CyP-1, Cyp-1, cyp1, CG9916, BcDNA:GM09255, Cyp1, CyP1" "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG9916 11-Aug-17 DroID_v2017_08 "Drer\LOC103911964, Drer\ppie, Drer\ppifb, Drer\nktr, Drer\ppil6, Drer\si:ch1073-55a19.2, Drer\LOC100333141, Drer\ppiaa, Drer\ppig, Drer\ppih, Drer\ppib, Drer\ppid, Drer\ppifa, Drer\ppiab" "Scer\CPR3, Scer\CPR6, Scer\CPR4, Scer\CPR1" "Cele\cyn-9, Cele\cyn-7, Cele\T22F3.12, Cele\cyn-11, Cele\cyn-6, Cele\cyn-5, Cele\cyn-2, Cele\cyn-8, Cele\cyn-1, Cele\cyn-3, Cele\Y17G9B.4" "Xtro\ppid, Xtro\ranbp2, Xtro\ppie, Xtro\ppil6, Xtro\ppif, Xtro\ppib, Xtro\ppia, Xtro\ppic, Xtro\ppih, Xtro\nktr" "Mmus\Ppid, Mmus\Ppib, Mmus\Nktr, Mmus\Ppig, Mmus\Ppih, Mmus\Ppic, Mmus\Ppif, Mmus\Ppil6, Mmus\Ppia, Mmus\Ranbp2, Mmus\Ppie" "Hsap\LOC105371242, Hsap\PPIF, Hsap\PPIA, Hsap\NKTR, Hsap\PPIG, Hsap\PPIL6, Hsap\PPIAL4A, Hsap\RGPD2, Hsap\PPIAL4C, Hsap\PPID, Hsap\RGPD5, Hsap\PPIH, Hsap\RGPD4, Hsap\PPIC, Hsap\RGPD1, Hsap\PPIB, Hsap\RGPD8, Hsap\RANBP2, Hsap\RGPD3, Hsap\PPIAL4E, Hsap\RGPD6, Hsap\PPIE, Hsap\PPIAL4D, Hsap\PPIAL4G" larval stage | third instar dorsal mesothoracic disc

"lethal,recessive,viable,visible" trichogen cell FBgn0265589 CR44416 - http://flybase.org/reports/FBgn0265589 non_protein_coding_gene - - - CR44416 - CR44416 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046330 l(2)38ABb lethal (2) 38ABb http://flybase.org/reports/FBgn0046330 gene - - - "lethal in 38A/B, l(2)38ABb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035953 CG5087 - http://flybase.org/reports/FBgn0035953 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:4868 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:4868 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:4868 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:4868 "CG5087, NM_140022.1" "IPR000048:IQ motif, EF-hand binding site, IPR000569:HECT domain" CG5087 11-Aug-17 DroID_v2017_08 "Drer\ube3c, Drer\ube3b" Scer\HUL5 "Cele\oxi-1, Cele\D2085.4" "Xtro\ube3b, Xtro\ube3c" "Mmus\Ube3c, Mmus\Ube3b" "Hsap\UBE3C, Hsap\UBE3B" viable FBgn0036443 CG13471 - http://flybase.org/reports/FBgn0036443 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13471 - CG13471 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040821 CG14148 - http://flybase.org/reports/FBgn0040821 protein_coding_gene - - - CG14148 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259214 PMCA plasma membrane calcium ATPase http://flybase.org/reports/FBgn0259214 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006408, InterPro:IPR030319 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250 calcium-transporting ATPase activity ; GO:0005388 | inferred from biological aspect of ancestor with PANTHER:PTN000643812" "calcium ion transmembrane transport ; GO:0070588 | inferred from electronic annotation with InterPro:IPR006408, InterPro:IPR030319 cellular calcium ion homeostasis ; GO:0006874 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000642960 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000642960 "PMCA, CK02288, BEST:CK01140, BEST:CK02288, CG2165, BP1021, CG34036, CG42314, BEST:CK" "IPR023299:P-type ATPase, cytoplasmic domain N, IPR018303:P-type ATPase, phosphorylation site, IPR001757:P-type ATPase, IPR004014:Cation-transporting P-type ATPase, N-terminal, IPR006068:Cation-transporting P-type ATPase, C-terminal, IPR006408:P-type ATPase, subfamily IIB, IPR008250:P-type ATPase, A domain, IPR022141:Plasma membrane calcium transporting P-type ATPase, C-terminal, IPR023214:HAD-like domain, IPR023298:P-type ATPase, transmembrane domain" CG42314 11-Aug-17 DroID_v2017_08 "Drer\atp2b4, Drer\atp2b1a, Drer\atp2b3a, Drer\atp2b1b, Drer\atp2b3b, Drer\atp2b2" Scer\PMC1 "Cele\mca-3, Cele\mca-2, Cele\mca-1" "Xtro\atp2b3, Xtro\atp2b2, Xtro\LOC100488346" "Mmus\Atp2b1, Mmus\Atp2b2, Mmus\Atp2b3, Mmus\Atp2b4" "Hsap\ATP2B1, Hsap\ATP2B3, Hsap\ATP2B2, Hsap\ATP2B4" FBgn0030342 CG10347 - http://flybase.org/reports/FBgn0030342 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:24306 "CG10347, Q9VYT5, HSP20" "IPR007052:CS domain, IPR008978:HSP20-like chaperone" CG10347 11-Aug-17 DroID_v2017_08 Drer\nudcd1 - Cele\C44E4.5 Xtro\nudcd1 Mmus\Nudcd1 Hsap\NUDCD1 viable FBgn0000602 E(var)301 Enhancer of variegation 301 http://flybase.org/reports/FBgn0000602 - gene - - - "En(var)301, E(var)301" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,enhancer of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0266509 s-454 - http://flybase.org/reports/FBgn0266509 gene - - - s-454 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066072 Su(var)2-14 Su(var)2-14 http://flybase.org/reports/FBgn0066072 gene - - - Su(var)2-14 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086265 psd palisade http://flybase.org/reports/FBgn0086265 protein_coding_gene - vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype follicle cell microvillus organization ; GO:0032529 | inferred from mutant phenotype chorion ; GO:0042600 | inferred from direct assay vitelline envelope ; GO:0060388 | inferred from direct assay "CG9050, TU-1, BcDNA:GM32356, psd, Fcp26Aa" - CG9050 11-Aug-17 DroID_v2017_08 - - - - - - adult stage && oogenesis stage | stage S8-10B oocyte | posterior

"female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "microvillus & follicle cell,vitelline membrane,microvillus & follicle celldm-PG45,cortical actin cytoskeleton & oocytedm-PG45" FBgn0015541 sda slamdance http://flybase.org/reports/FBgn0015541 FBgn0027573 protein_coding_gene aminopeptidase activity ; GO:0004177 | inferred from direct assay metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with kcc somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype regulation of membrane potential ; GO:0042391 | inferred from mutant phenotype cell dedifferentiation ; GO:0043697 | inferred from mutant phenotype mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "CG5518, BcDNA:GH07466, sda, Sda" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG5518 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-149p5.1, Drer\anpepb, Drer\si:ch211-106j24.1, Drer\enpep, Drer\anpepa, Drer\erap1b, Drer\npepps, Drer\erap2, Drer\si:ch211-198g19.1, Drer\si:ch211-276a23.5, Drer\erap1a, Drer\lnpep" "Scer\AAP1, Scer\TMA108, Scer\APE2" "Cele\T12E12.6, Cele\T07F10.1, Cele\R03G8.4, Cele\VB0395L.1, Cele\AC3.5, Cele\Y67D8C.9, Cele\T16G12.1, Cele\mnp-1, Cele\R03G8.6, Cele\F49B2.6, Cele\Y42A5A.1, Cele\pam-1, Cele\Y53F4B.20" "Xtro\enpep, Xtro\lvrn, Xtro\lnpep, Xtro\erap1, Xtro\anpep, Xtro\npepps" "Mmus\Lvrn, Mmus\Anpep, Mmus\Lnpep, Mmus\Enpep, Mmus\Trhde, Mmus\Erap1, Mmus\Npepps" "Hsap\TRHDE, Hsap\LNPEP, Hsap\ANPEP, Hsap\ERAP1, Hsap\ENPEP, Hsap\ERAP2, Hsap\LVRN, Hsap\NPEPPS" "viable,fertile,neurophysiology defective,bang sensitive,lethal,recessive,dominant,paralytic,drug conditional,semidominant,body color defective,planar polarity defective,partially lethal - majority die,some die during pupal stage" "aCC neuron,RP2 motor neuron,mesothoracic tergum" FBgn0019704 l(2)42Bd lethal (2) 42Bd http://flybase.org/reports/FBgn0019704 - gene - - - "l(2)4LL1, 4LL1, l(2)42Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267614 CR45952 - http://flybase.org/reports/FBgn0267614 non_protein_coding_gene - - - CR45952 - CR45952 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034788 CG13532 - http://flybase.org/reports/FBgn0034788 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG13532, CT32907" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG13532 11-Aug-17 DroID_v2017_08 "Drer\wu:fu71h07, Drer\zgc:194627, Drer\LOC797620" - - - "Mmus\Skint10, Mmus\Skint11" - viable FBgn0024907 anon-99Fb anon-99Fb http://flybase.org/reports/FBgn0024907 - gene - - - "K8, anon-99Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027972 l(3)S142603b lethal (3) S142603b http://flybase.org/reports/FBgn0027972 gene - - - "1426/03, l(3)S142603, l(3)S142603b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0061479 sorc sorciere http://flybase.org/reports/FBgn0061479 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sorc - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg,egg chamber,germline clone" FBgn0031573 CG3407 - http://flybase.org/reports/FBgn0031573 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR027775 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR027775" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR027775 "CG3407, cg3407" "IPR013087:Zinc finger C2H2-type, IPR027775:C2H2- zinc finger protein family subset" CG3407 11-Aug-17 DroID_v2017_08 "Drer\fezf2, Drer\fezf1, Drer\znf408, Drer\im:7147486, Drer\znf142" Scer\RME1 "Cele\lin-48, Cele\blmp-1, Cele\Y55F3AM.14" "Xtro\fezf1, Xtro\fezf2" "Mmus\Zfp142, Mmus\Zfp354b, Mmus\Zfp574, Mmus\Fezf1, Mmus\Zfp90, Mmus\Zfp354a, Mmus\Fezf2" "Hsap\ZFP90, Hsap\ZNF311, Hsap\KRBOX1, Hsap\ZNF142, Hsap\FEZF1, Hsap\ZNF354B, Hsap\ZNF574, Hsap\ZNF354A, Hsap\FEZF2" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0000337 cn cinnabar http://flybase.org/reports/FBgn0000337 - protein_coding_gene FAD binding ; GO:0071949 | inferred from electronic annotation with InterPro:IPR002938 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000350492 kynurenine 3-monooxygenase activity ; GO:0004502 | traceable author statement kynurenine 3-monooxygenase activity ; GO:0004502 | inferred from sequence or structural similarity with UniProtKB:Q86PM2 NAD(P)H oxidase activity ; GO:0016174 | inferred from biological aspect of ancestor with PANTHER:PTN000350492 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 quinolinate biosynthetic process ; GO:0019805 | inferred from electronic annotation with InterPro:IPR027545 tryptophan catabolic process ; GO:0006569 | inferred from electronic annotation with InterPro:IPR027545 ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype positive regulation of neuron death ; GO:1901216 | inferred from mutant phenotype NAD metabolic process ; GO:0019674 | inferred from biological aspect of ancestor with PANTHER:PTN000350493 tryptophan catabolic process ; GO:0006569 | traceable author statement kynurenine metabolic process ; GO:0070189 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | traceable author statement NAD metabolic process ; GO:0019674 | inferred from sequence or structural similarity with UniProtKB:Q86PM2 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:O88867 "cn, Dmel\cn, CG1555, KMO" "IPR002938:FAD-binding domain, IPR027545:Kynurenine 3-monooxygenase, IPR023753:FAD/NAD(P)-binding domain" CG1555 11-Aug-17 DroID_v2017_08 Drer\kmo Scer\BNA4 "Cele\kmo-2, Cele\kmo-1" Xtro\kmo Mmus\Kmo Hsap\KMO larval stage--pupal stage "eye color defective,recessive,visible,male sterile,female sterile,viable" "pigment cell,ocellus,ocellus pigment granule,Malpighian tubule" FBgn0030311 CG11699 - http://flybase.org/reports/FBgn0030311 protein_coding_gene - - - CG11699 IPR009792:Transmembrane protein 242 CG11699 11-Aug-17 DroID_v2017_08 Drer\tmem242 - Cele\F28D9.4 Xtro\tmem242 Mmus\Tmem242 Hsap\TMEM242 "viable,fertile,chemical sensitive,behavior defective" DRSC19419 K 0.631602312 0.51563869 -0.28271621 0.620936729 -1.95884653 -0.697266057 FBgn0054016 CG34016 - http://flybase.org/reports/FBgn0054016 protein_coding_gene - - - "BP1070, CG34016" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051676 CG31676 - http://flybase.org/reports/FBgn0051676 protein_coding_gene - - - "CG14404, CG14403, BcDNA:RH34376, CG31676" - CG31676 11-Aug-17 DroID_v2017_08 - - "Cele\K11H12.6, Cele\C15H9.9, Cele\K11H12.7" - - - "viable,fertile" FBgn0036519 CG7650 - http://flybase.org/reports/FBgn0036519 protein_coding_gene queuine tRNA-ribosyltransferase activity ; GO:0008479 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000239043 queuosine biosynthetic process ; GO:0008616 | inferred from biological aspect of ancestor with PANTHER:PTN000239043 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000239043 "BcDNA:AT27057, CG7650" "IPR001200:Phosducin, IPR012336:Thioredoxin-like fold, IPR024253:Phosducin, thioredoxin-like domain, IPR023196:Phosducin N-terminal domain" CG7650 11-Aug-17 DroID_v2017_08 "Drer\pdca, Drer\pdcl, Drer\pdcb" Scer\PLP2 "Cele\txdc-9, Cele\mau-8" "Xtro\pdcl, Xtro\pdc" "Mmus\Pdcl, Mmus\Pdc" "Hsap\PDC, Hsap\PDCL" "viable,visible" mesothoracic tergum FBgn0032644 CG5131 - http://flybase.org/reports/FBgn0032644 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR019165 - - CG5131 "IPR019165:Peptidase M76, ATP23, IPR024079:Metallopeptidase, catalytic domain" CG5131 11-Aug-17 DroID_v2017_08 Drer\xrcc6bp1 Scer\ATP23 - Xtro\xrcc6bp1 Mmus\Xrcc6bp1 Hsap\ATP23 "viable,fertile" FBgn0013698 mt:tRNA:Leu-TAG mitochondrial transfer RNA:Leucine-TAG http://flybase.org/reports/FBgn0013698 FBgn0002867 tRNA_gene - - - "CR34093, mtdbD00006312, mt:tRNA:Leu-TAG, mt:tRNA:L:CUN, tRNA[Leu(CUN)], mt:tRNA[Leu(CUN)]" - CR34093 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263212 CR43382 - http://flybase.org/reports/FBgn0263212 pseudogene_attribute - - - CR43382 - CR43382 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051922 CG31922 - http://flybase.org/reports/FBgn0051922 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR013085 molecular_function ; GO:0003674 | no biological data available "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with HGNC:28046" small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000420170 U12-type spliceosomal complex ; GO:0005689 | inferred from sequence or structural similarity with HGNC:28046 "20K, anon-AE003587.1, CG31922" "IPR013085:U1-C, C2H2-type zinc finger, IPR013087:Zinc finger C2H2-type" CG31922 11-Aug-17 DroID_v2017_08 Drer\zmat5 Scer\YHC1 - "Xtro\zmat5, Xtro\snrpc" "Mmus\Snrpc, Mmus\Zmat5" "Hsap\ZMAT5, Hsap\SNRPC" viable FBgn0036218 Sprn Spermitin http://flybase.org/reports/FBgn0036218 protein_coding_gene - intracellular transport ; GO:0046907 | inferred from electronic annotation with InterPro:IPR000156 Nebenkern ; GO:0016006 | inferred from direct assay "CG14128, Sprn, sprn" "IPR011993:PH domain-like, IPR000156:Ran binding domain" CG14128 11-Aug-17 DroID_v2017_08 Drer\si:ch211-232d19.4 - - Xtro\ccdc181 Mmus\Ccdc181 Hsap\CCDC181 viable FBgn0267266 CR45702 - http://flybase.org/reports/FBgn0267266 non_protein_coding_gene - - - CR45702 - CR45702 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017632 Eig12E Eig12E http://flybase.org/reports/FBgn0017632 - gene - - - "Eig12, Eig12E" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060372 l(3)S136808b lethal (3) S136808b http://flybase.org/reports/FBgn0060372 gene - - - "1368/08, l(3)S136808b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034468 Obp56a Odorant-binding protein 56a http://flybase.org/reports/FBgn0034468 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush response to pheromone ; GO:0019236 | inferred from sequence or structural similarity with UniProtKB:O02372 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 olfactory behavior ; GO:0042048 | inferred from sequence or structural similarity with UniProtKB:O02372 sensory perception of smell ; GO:0007608 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:O02372 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "56a, CG11797, BcDNA:RE46170, Obp56a, obp56a, DmelObp56a" IPR006170:Pheromone/general odorant binding protein CG11797 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC06085 E -0.245131351 1.157026317 -0.069054714 1.544745426 -0.91077311 -0.118708152 FBgn0003704 thvd thick vein delta http://flybase.org/reports/FBgn0003704 - gene - - - "dtv, thvd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,viable,male,reduced,visible,recessive" "wing,wing vein,wing vein L2,anal plate,genital arch,genitalia" FBgn0002194 l(3)63Be lethal (3) 63Be http://flybase.org/reports/FBgn0002194 - gene - - - l(3)63Be - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0020837 l(2)F9 Florida 9 http://flybase.org/reports/FBgn0020837 - gene - - - "l(2)Fla.'9, l(2)F9" - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0003291 Rst(3)ns Resistant to nicotine http://flybase.org/reports/FBgn0003291 - gene - - - Rst(3)ns - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0003686 tfd two-faced http://flybase.org/reports/FBgn0003686 - gene - - - tfd - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,head bristle,adult cuticle,ocellus,antenna,labellum,eye-antennal disc" FBgn0024633 l(2)k14039 lethal (2) k14039 http://flybase.org/reports/FBgn0024633 - gene - - - "140/39, l(2)k14039" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0085343 Sws1 SWIM domain containing Srs2 interacting protein 1 http://flybase.org/reports/FBgn0085343 protein_coding_gene - - - "Sws1, CG34314, dmSws1, Dromel_CG3240_FBtr0077747_rad1_uORF" - CG34314 11-Aug-17 DroID_v2017_08 Drer\rad1 - Cele\mrt-2 Xtro\rad1 Mmus\Rad1 Hsap\RAD1 FBgn0030504 CG2691 - http://flybase.org/reports/FBgn0030504 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q12754 "CG2691, RRP12" "IPR012978:Uncharacterised domain NUC173, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG2691 11-Aug-17 DroID_v2017_08 Drer\rrp12 Scer\RRP12 Cele\Y46E12BL.2 Xtro\rrp12 Mmus\Rrp12 Hsap\RRP12 "viable,fertile" FBgn0002136 l(2)K225 lethal (2) K225 http://flybase.org/reports/FBgn0002136 - gene - - - l(2)K225 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259704 Nsun5 Nop2/Sun-like domain containing protein 5 http://flybase.org/reports/FBgn0259704 protein_coding_gene S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from biological aspect of ancestor with PANTHER:PTN000515868 RNA methyltransferase activity ; GO:0008173 | inferred from biological aspect of ancestor with PANTHER:PTN000515868 rRNA base methylation ; GO:0070475 | inferred from biological aspect of ancestor with PANTHER:PTN000515911 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000515911 "CG5558, Nsun5, CG42358, dNsun5" "IPR001678:SAM-dependent methyltransferase RsmB/NOP2-type, IPR023267:RNA (C5-cytosine) methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG42358 11-Aug-17 DroID_v2017_08 Drer\nsun5 Scer\RCM1 Cele\nsun-5 Xtro\nsun5 "Mmus\Nsun5, Mmus\Nsun7" "Hsap\NSUN5, Hsap\NSUN7" viable FBgn0033238 azot ahuizotl http://flybase.org/reports/FBgn0033238 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype - "BcDNA:AT10229, BcDNA:AT23738, azot, CG11165, CBP2" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG11165 11-Aug-17 DroID_v2017_08 "Drer\cabp1b, Drer\pvalb2, Drer\pvalb3, Drer\calb2a, Drer\calm3b, Drer\pvalb4, Drer\calm2b, Drer\tnnc1a, Drer\si:ch211-197n1.2, Drer\rhbdl3, Drer\cabp5b, Drer\calm1a, Drer\efcab2, Drer\scgn, Drer\calm2a, Drer\pvalb9, Drer\efcab11, Drer\caln1, Drer\calml4b, Drer\calb2b, Drer\cabp4, Drer\caln2, Drer\tnnc2, Drer\cabp5a, Drer\cabp2a, Drer\calm1b, Drer\efcab6, Drer\pvalb6, Drer\pvalb8, Drer\tnnc1b, Drer\pvalb1, Drer\cabp1a, Drer\calm3a, Drer\calml4a, Drer\cabp2b, Drer\cabp7b, Drer\calb1" "Scer\MLC1, Scer\CMD1, Scer\MLC2" "Cele\tnc-2, Cele\cmd-1, Cele\cal-1, Cele\cal-3, Cele\cal-2, Cele\cal-4" "Xtro\LOC548651, Xtro\pvalb.2, Xtro\calm1, Xtro\scgn, Xtro\tnnc1, Xtro\calb1, Xtro\pvalb, Xtro\cabp4, Xtro\ocm.2, Xtro\tnnc2, Xtro\ocm, Xtro\pgm1, Xtro\efcab6, Xtro\calml4, Xtro\calm2, Xtro\cabp7, Xtro\pvalb.1" "Mmus\Efcab3, Mmus\Cabp2, Mmus\Calml4, Mmus\Tnnc1, Mmus\Calm5, Mmus\Efcab7, Mmus\Cabp7, Mmus\Calm4, Mmus\Efcab6, Mmus\Caln1, Mmus\1700023F06Rik, Mmus\Tnnc2, Mmus\Rhbdl3, Mmus\Pvalb, Mmus\Cabp5, Mmus\Calb1, Mmus\Cabp1, Mmus\Scgn, Mmus\Spata21, Mmus\Calm1, Mmus\Efcab11, Mmus\Calml3, Mmus\Ocm, Mmus\Cabp4, Mmus\Calm3, Mmus\Calb2, Mmus\Efcab9, Mmus\Efcab2, Mmus\Calm2" "Hsap\CALM2, Hsap\OCM, Hsap\CALB2, Hsap\CABP1, Hsap\TNNC2, Hsap\CALB1, Hsap\SCGN, Hsap\CALM3, Hsap\CALM1, Hsap\EFCAB6, Hsap\CALML4, Hsap\EFCAB2, Hsap\EFCAB13, Hsap\EFCAB7, Hsap\CABP5, Hsap\PVALB, Hsap\CALML6, Hsap\OCM2, Hsap\CABP2, Hsap\CABP4, Hsap\CALML3, Hsap\C2orf61, Hsap\EFCAB11, Hsap\EFCAB3, Hsap\SPATA21, Hsap\RHBDL3, Hsap\CABP7, Hsap\CALML5, Hsap\CALN1, Hsap\TNNC1, Hsap\EFCAB9" viable FBgn0033600 Cpr47Ec Cuticular protein 47Ec http://flybase.org/reports/FBgn0033600 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr47Ec, CG9077, DmelCpr47Ec, Cpr47eg" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG9077 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0265095 CR44200 - http://flybase.org/reports/FBgn0265095 non_protein_coding_gene - - - "CR44200, lincRNA.260" - CR44200 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001874 l(1)XN75b lethal (1) XN75b http://flybase.org/reports/FBgn0001874 - gene - - - l(1)XN75b - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002763 mit(1)13 mitotic 13 http://flybase.org/reports/FBgn0002763 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0005726 l(1)TK136 lethal (1) TK136 http://flybase.org/reports/FBgn0005726 - gene - - - "l136, l(1)TK136" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "eye,lamina,retina,photoreceptor cell,ectopic" FBgn0284408 trol terribly reduced optic lobes http://flybase.org/reports/FBgn0284408 protein_coding_gene - maintenance of epithelial cell apical/basal polarity ; GO:0045199 | inferred from mutant phenotype response to anesthetic ; GO:0072347 | inferred from mutant phenotype defasciculation of motor neuron axon ; GO:0007415 | inferred from mutant phenotype positive regulation of semaphorin-plexin signaling pathway ; GO:2001262 | inferred from genetic interaction with Sema1a inferred from genetic interaction with PlexA motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay basement membrane ; GO:0005604 | inferred from sequence or structural similarity nucleoplasm ; GO:0005654 | inferred from direct assay "trol, Pcan, CG7981, TROL, CG33950, Trol, Troll, CG12497, CT23996, pcan, GC7891, EG:BACR25B3.10, EG:BACR25B3.1, EG:BACR25B3.11, EG:BACR25B3.2, l(1)3Ac, zw-1, l(1)trol, zw1, l(1)zw1, l(1)zwl, ZW-1, troll, l(1)VA51, l(1)9-96, CG33675, BcDNA:GM02481, anon-WO0153538.72, l(1)G0023, l(1)G0271, l(1)G0374, Trol-A, Trol-B, MRE7, l(1)G0021, l(1)G0181, l(1)G0412, l(1)G0019, l(1)G0211" "IPR032984:Hemicentin-1/2, IPR000082:SEA domain, IPR013151:Immunoglobulin, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR000034:Laminin IV, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR002049:Laminin EGF domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG33950 11-Aug-17 DroID_v2017_08 "Drer\lama4, Drer\hspg2, Drer\egflam, Drer\agrn, Drer\sid4, Drer\LOC101884253" - "Cele\T19D12.6, Cele\unc-52, Cele\agr-1" "Xtro\egflam, Xtro\LOC100491172, Xtro\agrn, Xtro\hspg2" "Mmus\Egflam, Mmus\Agrn, Mmus\Hspg2" "Hsap\EGFLAM, Hsap\EYS, Hsap\HSPG2, Hsap\AGRN" "lethal - all die before end of larval stage,some die during larval stage" FBgn0052698 CG32698 - http://flybase.org/reports/FBgn0052698 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG9683, CG9678, CG32698" "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class" CG32698 11-Aug-17 DroID_v2017_08 "Drer\ca12, Drer\ca9, Drer\ca2, Drer\ca6, Drer\ca10a, Drer\ca15c, Drer\ca16b, Drer\ca4a, Drer\cahz, Drer\ca4b, Drer\zgc:153760, Drer\ca7, Drer\car15, Drer\ca8, Drer\ca10b, Drer\ca15a, Drer\ca14, Drer\ca15b, Drer\ca5a, Drer\ca4c, Drer\ptprga" - "Cele\cah-1, Cele\cah-2" "Xtro\ca4, Xtro\ca3, Xtro\ca8, Xtro\ca14, Xtro\ca5b, Xtro\ca10, Xtro\ca1, Xtro\ca12, Xtro\ca2, Xtro\ca11, Xtro\LOC779564, Xtro\ca6, Xtro\ca7" "Mmus\Car7, Mmus\Car4, Mmus\Car15, Mmus\Car5b, Mmus\Car9, Mmus\Car13, Mmus\Car1, Mmus\Car14, Mmus\Car10, Mmus\Car11, Mmus\Car8, Mmus\Car12, Mmus\Car2, Mmus\Car6, Mmus\Ptprg, Mmus\Car5a, Mmus\Car3" "Hsap\CA1, Hsap\PTPRG, Hsap\CA7, Hsap\CA2, Hsap\CA12, Hsap\CA8, Hsap\CA9, Hsap\CA4, Hsap\CA11, Hsap\CA3, Hsap\CA10, Hsap\CA6, Hsap\CA5A, Hsap\CA13, Hsap\CA14, Hsap\CA5B" "viable,fertile,lethal" FBgn0001909 l(2)24Fa lethal (2) 24Fa http://flybase.org/reports/FBgn0001909 - gene - - - "jf6, l(2)jf6, l(2)jf5, l(2)24Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065589 l(2)SH0906 lethal (2) SH0906 http://flybase.org/reports/FBgn0065589 gene - - - "l(2)SH0906, l(2)SH2 0906" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069965 CG41042 - http://flybase.org/reports/FBgn0069965 protein_coding_gene - - - CG41042 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000036 nAChRalpha1 nicotinic Acetylcholine Receptor alpha1 http://flybase.org/reports/FBgn0000036 - protein_coding_gene acetylcholine receptor activity ; GO:0015464 | contributes_to inferred from direct assay acetylcholine-gated cation channel activity ; GO:0022848 | contributes_to inferred from direct assay acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity "cation transport ; GO:0006812 | inferred from direct assay response to insecticide ; GO:0017085 | inferred from mutant phenotype synaptic transmission, cholinergic ; GO:0007271 | inferred from expression pattern" postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated channel complex ; GO:0005892 | inferred from direct assay acetylcholine-gated channel complex ; GO:0005892 | inferred from physical interaction with nAChRα2 acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity "CG5610, nAcRalpha-96Aa, nAChR, ALS, nAcr96Aa, nAcRs, Acr96Aa, als, alpha1, alpha-like, ALs, AcrB, Acr96A, dALS, nAChRalpha1, CG5610-PA, Dalpha1, nAChRalpha-96Aa, NAcRa96Aa, nAChR-alpha96Aa" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG5610 11-Aug-17 DroID_v2017_08 "Drer\chrna5, Drer\htr3b, Drer\si:ch211-256e16.4, Drer\htr3a, Drer\chrnb4, Drer\LOC798522, Drer\chrna2b, Drer\chrnb1l, Drer\chrng, Drer\chrnb2a, Drer\LOC101882451, Drer\si:ch73-380n15.2, Drer\chrna6, Drer\chrne, Drer\chrnb2l, Drer\chrnb3b, Drer\chrnb1, Drer\si:ch211-39a7.1, Drer\chrna2a, Drer\chrnb2b, Drer\chrnb3a, Drer\chrna3, Drer\chrna4b, Drer\chrna9, Drer\chrna1, Drer\chrna10a, Drer\chrnd" - "Cele\unc-63, Cele\acr-15, Cele\acr-9, Cele\acr-2, Cele\acr-7, Cele\lgc-4, Cele\acr-14, Cele\acr-8, Cele\unc-38, Cele\acr-3, Cele\acr-12, Cele\acr-11, Cele\acr-10, Cele\lev-1, Cele\eat-2, Cele\acr-19, Cele\acr-21, Cele\lev-8, Cele\acr-6, Cele\acr-25, Cele\acr-16" "Xtro\chrna7, Xtro\chrna6, Xtro\chrna9, Xtro\chrna1, Xtro\chrna1.2, Xtro\chrna2, Xtro\chrnd, Xtro\chrng, Xtro\chrna5, Xtro\chrnb3, Xtro\chrnb2, Xtro\chrne" "Mmus\Chrnb1, Mmus\Chrne, Mmus\Chrng, Mmus\Chrna4, Mmus\Chrna3, Mmus\Chrnb2, Mmus\Chrna9, Mmus\Htr3b, Mmus\Chrna6, Mmus\Chrna1, Mmus\Htr3a, Mmus\Chrnb3, Mmus\Chrna7, Mmus\Chrnb4, Mmus\Chrna10, Mmus\Chrnd, Mmus\Chrna2, Mmus\Chrna5" "Hsap\CHRND, Hsap\HTR3D, Hsap\CHRNG, Hsap\CHRNB3, Hsap\CHRNA6, Hsap\CHRNB4, Hsap\CHRFAM7A, Hsap\CHRNA1, Hsap\CHRNE, Hsap\CHRNB2, Hsap\CHRNA5, Hsap\HTR3A, Hsap\HTR3B, Hsap\CHRNA7, Hsap\CHRNA3, Hsap\CHRNA4, Hsap\HTR3E, Hsap\HTR3C, Hsap\CHRNA9, Hsap\CHRNA10, Hsap\CHRNA2, Hsap\CHRNB1" larval stage " larval brain | restricted

, fat body

" "viable,chemical resistant,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0036754 CG5589 - http://flybase.org/reports/FBgn0036754 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000003139 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000619239 - "DmRH17, cg5589, CG5589" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR014001:Helicase superfamily 1/2, ATP-binding domain" CG5589 11-Aug-17 DroID_v2017_08 Drer\ddx52 Scer\ROK1 Cele\R05D11.4 Xtro\ddx52 Mmus\Ddx52 Hsap\DDX52 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0050376 CG30376 - http://flybase.org/reports/FBgn0050376 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT30260, CG30376" - CG30376 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0065400 l(2)SH1604 lethal (2) SH1604 http://flybase.org/reports/FBgn0065400 gene - - - "l(2)SH1604, l(2)SH2 1604" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031563 CG10031 - http://flybase.org/reports/FBgn0031563 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10031 IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG10031 11-Aug-17 DroID_v2017_08 "Drer\spint1b, Drer\col6a4a, Drer\spint2, Drer\spint1a, Drer\si:dkeyp-73b11.8, Drer\tfpi2, Drer\si:dkey-117n7.5, Drer\tfpia, Drer\ambp" - "Cele\mlt-11, Cele\mec-9, Cele\mec-1" "Xtro\spint1, Xtro\spint2, Xtro\ambp, Xtro\tfpi2" "Mmus\Spint4, Mmus\Spint5, Mmus\Tfpi2, Mmus\Wfdc8, Mmus\Wfdc6b, Mmus\Spint3, Mmus\Spint2, Mmus\Col28a1, Mmus\Eppin, Mmus\Spint1, Mmus\Wfdc6a, Mmus\Ambp, Mmus\Tfpi" "Hsap\WFDC6, Hsap\SPINT2, Hsap\EPPIN-WFDC6, Hsap\TFPI, Hsap\SPINT3, Hsap\TFPI2, Hsap\SPINT4, Hsap\AMBP, Hsap\WFDC8, Hsap\SPINT1" viable DRSC00286 K 0.083435295 -0.381492381 0.469131226 -0.019625059 -0.673698093 -1.724764975 FBgn0260940 lsn larsen http://flybase.org/reports/FBgn0260940 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell proliferation ; GO:0008283 | inferred from mutant phenotype bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype parturition ; GO:0007567 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype multivesicular body assembly ; GO:0036258 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from mutant phenotype protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043328 | inferred from biological aspect of ancestor with PANTHER:PTN000301561 regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from expression pattern regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype ESCRT II complex ; GO:0000814 | inferred from sequence or structural similarity with SGD:S000005923 ESCRT II complex ; GO:0000814 | inferred from biological aspect of ancestor with PANTHER:PTN000301561 "lsn, Vps22, vps22, CG6637, Lsn" "IPR007286:EAP30, IPR016689:ESCRT-2 complex, Snf8, IPR011991:Winged helix-turn-helix DNA-binding domain" CG6637 11-Aug-17 DroID_v2017_08 Drer\snf8 Scer\SNF8 Cele\vps-22 Xtro\snf8 Mmus\Snf8 Hsap\SNF8 FBgn0069986 BG02131 BG02131 http://flybase.org/reports/FBgn0069986 gene - - - BG02131 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0060559 l(3)S097201b lethal (3) S097201b http://flybase.org/reports/FBgn0060559 gene - - - "0972/01, l(3)S097201b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0040606 CG6503 - http://flybase.org/reports/FBgn0040606 protein_coding_gene - - - "pncr007:3R, CT20261, BcDNA:RH63361, CG6503" - CG6503 11-Aug-17 DroID_v2017_08 - - Cele\C17E4.4 - - - viable FBgn0263554 mir-4952 mir-4952 stem loop http://flybase.org/reports/FBgn0263554 miRNA_gene - - - "mir-4952, dme-mir-4952, CR43539" - CR43539 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036891 CG9372 - http://flybase.org/reports/FBgn0036891 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype response to fungus ; GO:0009620 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence model" - "c-SP34, SP34, CG9372" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site, IPR022700:Proteinase, regulatory CLIP domain" CG9372 11-Aug-17 DroID_v2017_08 "Drer\ctrb1, Drer\si:dkey-57c15.4, Drer\ela3l, Drer\si:dkey-238d18.3, Drer\zgc:112368, Drer\zgc:112285, Drer\zgc:92745, Drer\zgc:112160, Drer\zgc:154142, Drer\st14b, Drer\ela2l, Drer\zgc:171592, Drer\zgc:92511, Drer\ela2, Drer\zgc:92041, Drer\ctrl, Drer\zgc:112302, Drer\LOC562139" - "Cele\try-1, Cele\try-3, Cele\svh-1" "Xtro\ctrb2, Xtro\LOC100135144, Xtro\ctrb1, Xtro\cela3a, Xtro\proc, Xtro\cela2a, Xtro\proz" "Mmus\Cela3a, Mmus\Ctrl, Mmus\Ctrb1, Mmus\Prss12, Mmus\Cela1, Mmus\Ctrc, Mmus\Proz, Mmus\Cela2a, Mmus\Cela3b" "Hsap\CTRB2, Hsap\CELA1, Hsap\CELA3B, Hsap\PROZ, Hsap\CTRC, Hsap\CELA2A, Hsap\CTRB1, Hsap\CTRL, Hsap\CELA3A, Hsap\CELA2B, Hsap\PRSS12" viable FBgn0026228 l(1)16Fm lethal (1) 16Fm http://flybase.org/reports/FBgn0026228 - gene - - - "HL-XII, l(1)16Fm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039707 Prtl99C Protamine-like 99C http://flybase.org/reports/FBgn0039707 protein_coding_gene - sperm chromatin condensation ; GO:0035092 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG15510, BcDNA:AT14346, Prtl99C" "IPR009071:High mobility group box domain, IPR024460:Protamine-like" CG15510 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034551 CG15225 - http://flybase.org/reports/FBgn0034551 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model CG15225 - CG15225 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031224 CG11454 - http://flybase.org/reports/FBgn0031224 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity single-stranded RNA binding ; GO:0003727 | inferred from biological aspect of ancestor with PANTHER:PTN001012985 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from biological aspect of ancestor with PANTHER:PTN001012985" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001012985 "cg11454, CG11454, dRbm7" IPR000504:RNA recognition motif domain CG11454 11-Aug-17 DroID_v2017_08 "Drer\rbm11, Drer\rbm7" "Scer\HSH49, Scer\RNA15" "Cele\cpf-2, Cele\Y37D8A.21, Cele\M01D7.9, Cele\rnp-8" "Xtro\rbm7, Xtro\rbm11" "Mmus\Rbm7, Mmus\Rbm11" "Hsap\RBM11, Hsap\RBM7" viable FBgn0066349 l(3)99DEf lethal (3) 99DEf http://flybase.org/reports/FBgn0066349 gene - - - l(3)99DEf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003965 v vermilion http://flybase.org/reports/FBgn0003965 - protein_coding_gene "heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000015587 tryptophan 2,3-dioxygenase activity ; GO:0004833 | traceable author statement heme binding ; GO:0020037 | inferred from direct assay tryptophan 2,3-dioxygenase activity ; GO:0004833 | inferred from direct assay heme binding ; GO:0020037 | inferred from sequence or structural similarity with UniProtKB:Q17P71 tryptophan 2,3-dioxygenase activity ; GO:0004833 | inferred from sequence or structural similarity with UniProtKB:Q17P71" compound eye pigmentation ; GO:0048072 | traceable author statement tryptophan catabolic process ; GO:0006569 | traceable author statement positive regulation of neuron death ; GO:1901216 | inferred from mutant phenotype tryptophan catabolic process to acetyl-CoA ; GO:0019442 | inferred from biological aspect of ancestor with PANTHER:PTN000015587 tryptophan catabolic process to kynurenine ; GO:0019441 | inferred from direct assay kynurenine metabolic process ; GO:0070189 | inferred from mutant phenotype protein homotetramerization ; GO:0051289 | inferred from direct assay tryptophan catabolic process to kynurenine ; GO:0019441 | inferred from sequence or structural similarity with UniProtKB:Q17P71 ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype - "v, vm, 152559_at, NP_511113, Ver, CG2155, ver, DmTDO, TDO" "IPR004981:Tryptophan 2,3-dioxygenase" CG2155 11-Aug-17 DroID_v2017_08 "Drer\tdo2b, Drer\tdo2a" - Cele\tdo-2 Xtro\tdo2 Mmus\Tdo2 Hsap\TDO2 " adult stage , embryonic stage -- adult stage "

{ ^ su(s)35 } "fertile,viable,visible,recessive,eye color defective,male,long lived,male sterile,wild-type,male fertile,lethal,body color defective,female sterile,sterile" "pigment cell,ocellus pigment granule,eye" FBgn0040097 lectin-30A lectin-30A http://flybase.org/reports/FBgn0040097 protein_coding_gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG17011, AC005889a, AC 005889A, lectin-30A, Lectin-30A" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG17011 11-Aug-17 DroID_v2017_08 "Drer\hbl4, Drer\hbl3, Drer\si:dkey-88n24.7, Drer\clec11a, Drer\colec11, Drer\hbl2" - Cele\clec-149 - "Mmus\Mbl1, Mmus\Cd209g, Mmus\Colec11" "Hsap\CD209, Hsap\CLEC3B, Hsap\SFTPD, Hsap\COLEC10, Hsap\COLEC11" "viable,visible" "trichogen cell,mesothoracic tergum" DRSC02560 K 0.80405199 0.220464309 0.357874715 -0.161842736 1.059307675 1.62267659 FBgn0264476 CR43884 - http://flybase.org/reports/FBgn0264476 non_protein_coding_gene - - - CR43884 - CR43884 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053958 CG33958 - http://flybase.org/reports/FBgn0053958 protein_coding_gene guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 guanylate cyclase activity ; GO:0004383 | non-traceable author statement "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "GYC, CG14501, CG5719, CG33958" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase, IPR013587:Nitrate/nitrite sensing protein, IPR011645:Haem NO binding associated" CG33958 11-Aug-17 DroID_v2017_08 "Drer\npr1b, Drer\gc3, Drer\gc2, Drer\gucy2c, Drer\si:dkey-37g12.1, Drer\gucy2f, Drer\npr3, Drer\gucy2g, Drer\si:ch73-139e5.4, Drer\npr1a" - "Cele\gcy-23, Cele\gcy-27, Cele\acy-3, Cele\gcy-12, Cele\gcy-18, Cele\gcy-37" "Xtro\gucy2f, Xtro\npr1, Xtro\npr3, Xtro\gucy2d, Xtro\gucy2c" "Mmus\Npr2, Mmus\Npr1, Mmus\Npr3, Mmus\Gucy2c, Mmus\Gucy2d, Mmus\Gucy2e, Mmus\Gucy2f, Mmus\Gucy2g" "Hsap\GUCY2C, Hsap\NPR2, Hsap\NPR3, Hsap\NPR1, Hsap\GUCY2F, Hsap\GUCY2D" "viable,fertile" FBgn0277423 l(3)psg27 - http://flybase.org/reports/FBgn0277423 gene - - - "l(3)psg27, psg27" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028735 F8 F8 http://flybase.org/reports/FBgn0028735 gene - - - F8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020282 l(3)rF149 lethal (3) rF149 http://flybase.org/reports/FBgn0020282 - gene - - - l(3)rF149 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062521 lgs::pygo lgs::pygo http://flybase.org/reports/FBgn0062521 engineered_fusion_gene - - - lgs::pygo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028533 CG7953 - http://flybase.org/reports/FBgn0028533 protein_coding_gene - - - "DS00941.14, BG:DS00941.14, anon-WO0140519.73, CG7953" IPR010562:Haemolymph juvenile hormone binding CG7953 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0058323 CG40323 - http://flybase.org/reports/FBgn0058323 protein_coding_gene - - - CG40323 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065431 l(2)SH1495 lethal (2) SH1495 http://flybase.org/reports/FBgn0065431 gene - - - "l(2)SH1495, l(2)SH2 1495" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030482 CG1673 - http://flybase.org/reports/FBgn0030482 protein_coding_gene branched-chain-amino-acid transaminase activity ; GO:0004084 | inferred from sequence or structural similarity with UniProtKB:O15382 branched-chain-amino-acid transaminase activity ; GO:0004084 | inferred from biological aspect of ancestor with PANTHER:PTN000214534 leucine biosynthetic process ; GO:0009098 | inferred from biological aspect of ancestor with PANTHER:PTN000214534 branched-chain amino acid biosynthetic process ; GO:0009082 | inferred from sequence or structural similarity with UniProtKB:O15382 valine biosynthetic process ; GO:0009099 | inferred from biological aspect of ancestor with PANTHER:PTN000214534 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O15382 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000214537 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:O15382 "CG1673, cg1673" "IPR001544:Aminotransferase class IV, IPR005786:Branched-chain amino acid aminotransferase II, IPR018300:Aminotransferase, class IV, conserved site, IPR033939:Branched-chain aminotransferase" CG1673 11-Aug-17 DroID_v2017_08 "Drer\bcat2, Drer\bcat1" "Scer\ABZ2, Scer\BAT1, Scer\BAT2" "Cele\Y44A6D.5, Cele\bcat-1" "Xtro\bcat2, Xtro\bcat1" "Mmus\Bcat2, Mmus\Bcat1" "Hsap\BCAT2, Hsap\BCAT1" "viable,body color defective" mesothoracic tergum FBgn0262617 CG43143 - http://flybase.org/reports/FBgn0262617 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 structural molecule activity ; GO:0005198 | inferred from biological aspect of ancestor with PANTHER:PTN000273496 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:14311 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:14311 protein phosphorylation ; GO:0006468 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:14311 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:14311 "CG11871, NUAK, CG43143, EMK/KIAA0537, CG11870, Omphk1, CG11872" "IPR017404:Ladinin 1, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG43143 11-Aug-17 DroID_v2017_08 "Drer\nuak1a, Drer\lad1, Drer\nuak1b, Drer\nuak2" Scer\SNF1 Cele\unc-82 "Xtro\nuak2, Xtro\nuak1" "Mmus\Lad1, Mmus\Nuak2, Mmus\Nuak1" "Hsap\NUAK2, Hsap\LAD1, Hsap\NUAK1" FBgn0064227 Rdh Rdh http://flybase.org/reports/FBgn0064227 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14975, Rdh" - CG14975 11-Aug-17 DroID_v2017_08 - - - - - - long lived FBgn0022394 Hex2 Hexokinase 2 http://flybase.org/reports/FBgn0022394 - gene - - - "HK, HEX, HEX-2, Hex2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034093 CG15706 - http://flybase.org/reports/FBgn0034093 protein_coding_gene - - - CG15706 "IPR024989:Major facilitator superfamily associated domain, IPR020846:Major facilitator superfamily domain" CG15706 11-Aug-17 DroID_v2017_08 "Drer\mfsd6b, Drer\mfsd6l, Drer\mfsd6a" - Cele\R13A5.9 "Xtro\mfsd6, Xtro\mfsd6l" "Mmus\Mfsd6l, Mmus\Mfsd6" "Hsap\MFSD6, Hsap\MFSD6L" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0265808 CR44597 - http://flybase.org/reports/FBgn0265808 non_protein_coding_gene - - - "lincRNA.119, CR44597" - CR44597 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014268 l(2)k08634 lethal (2) k08634 http://flybase.org/reports/FBgn0014268 - gene molecular_function ; GO:0003674 | no biological data available lymph gland development ; GO:0048542 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)86/34, l(2)k08634" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval brain,embryonic/larval lymph gland" FBgn0267220 CR45660 - http://flybase.org/reports/FBgn0267220 non_protein_coding_gene - - - CR45660 - CR45660 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028436 ECSIT ECSIT http://flybase.org/reports/FBgn0028436 protein_coding_gene "oxidoreductase activity, acting on NAD(P)H ; GO:0016651 | inferred from sequence or structural similarity with UniProtKB:Q9BQ95 protein binding ; GO:0005515 | inferred from physical interaction with Traf6" innate immune response ; GO:0045087 | inferred from direct assay regulation of oxidoreductase activity ; GO:0051341 | inferred from sequence or structural similarity with UniProtKB:Q9BQ95 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9BQ95 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9BQ95 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9BQ95 "DmECSIT, dECSIT, CG10610, ECSIT" "IPR010418:ECSIT, IPR029342:ECSIT, C-terminal domain" CG10610 11-Aug-17 DroID_v2017_08 Drer\ecsit - Cele\Y17G9B.5 Xtro\ecsit Mmus\Ecsit Hsap\ECSIT "viable,fertile" FBgn0060682 l(3)S076201b lethal (3) S076201b http://flybase.org/reports/FBgn0060682 gene - - - "0762/01, l(3)S076201b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0014217 l(2)31Cb lethal (2) 31Cb http://flybase.org/reports/FBgn0014217 - gene - - - l(2)31Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259263 EP-332 - http://flybase.org/reports/FBgn0259263 gene - - - EP-332 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0003306 Rw Rough wing http://flybase.org/reports/FBgn0003306 - gene - - - Rw - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,dominant" "wing,wing vein,antenna,ectopic" FBgn0259337 EP-23 - http://flybase.org/reports/FBgn0259337 gene - - - EP-23 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta" FBgn0085315 CG34286 - http://flybase.org/reports/FBgn0085315 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34286 - CG34286 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022307 l(1)L19.1 lethal (1) L19.1 http://flybase.org/reports/FBgn0022307 - gene - - - "L19.1, l(1)L19.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043561 Su(hh)VI Su(hh)VI http://flybase.org/reports/FBgn0043561 gene - - - Su(hh)VI - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263976 CR43728 - http://flybase.org/reports/FBgn0263976 non_protein_coding_gene - - - CR43728 - CR43728 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044095 E(rst)D17 E(rst)D17 http://flybase.org/reports/FBgn0044095 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D17, E(rst)D17" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028653 anon-47Ec anon-47Ec http://flybase.org/reports/FBgn0028653 gene - - - "3B1, anon-47Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039621 CG14518 - http://flybase.org/reports/FBgn0039621 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14518 IPR010512:Protein of unknown function DUF1091 CG14518 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0065154 l(3)SH054 lethal (3) SH054 http://flybase.org/reports/FBgn0065154 gene - - - "l(3)SH054, l(2)SH3 054" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022272 l(2)k00224 lethal (2) k00224 http://flybase.org/reports/FBgn0022272 - gene - - - l(2)k00224 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,wing vein,wing" FBgn0037892 mRpL40 mitochondrial ribosomal protein L40 http://flybase.org/reports/FBgn0037892 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AI760300 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AI760300 mitochondrial translation ; GO:0032543 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AI760300 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CG5242, MRPL22(24), mRpL22-24, mRpL40" "IPR019192:Ribosomal protein L28/L40, mitochondrial" CG5242 11-Aug-17 DroID_v2017_08 Drer\mrpl40 Scer\MRPL28 Cele\mrpl-40 Xtro\mrpl40 Mmus\Mrpl40 Hsap\MRPL40 "visible,partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective" "trichogen cell,mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell" FBgn0053169 CG33169 - http://flybase.org/reports/FBgn0053169 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "EP3524, CG8244, BcDNA:RH56317, CG33169" IPR027960:Domian of unknown function DUF4519 CG33169 11-Aug-17 DroID_v2017_08 Drer\smco4 - - Xtro\smco4 Mmus\Smco4 Hsap\SMCO4 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,female fertile" "intersegmental nerve,trichogen cell,mesothoracic tergum" FBgn0259339 EP-878 - http://flybase.org/reports/FBgn0259339 gene - - - EP-878 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0260266 GSd212 - http://flybase.org/reports/FBgn0260266 gene - - - GSd212 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0022743 anon-UJ4c anon-UJ4c http://flybase.org/reports/FBgn0022743 - gene - - - anon-UJ4c - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000667 Actn alpha actinin http://flybase.org/reports/FBgn0000667 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 actin binding ; GO:0003779 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Lasp protein binding ; GO:0005515 | inferred from physical interaction with rols actin binding ; GO:0003779 | inferred from physical interaction with UniProtKB:A1ZA47 actin filament binding ; GO:0051015 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from direct assay cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity sarcomere organization ; GO:0045214 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype Z disc ; GO:0030018 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from sequence or structural similarity "l(1)2Cb, fliA, actn, EG:133E12.1, CG4376, CT14232, CT14163, HM-29, GA17, l(1)EA82, alpha-actinin, y, Actn, ACTN, alphaActn" "IPR018159:Spectrin/alpha-actinin, IPR018247:EF-Hand 1, calcium-binding site, IPR001589:Actinin-type actin-binding domain, conserved site, IPR001715:Calponin homology domain, IPR002017:Spectrin repeat, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR014837:EF-hand, Ca insensitive" CG4376 11-Aug-17 DroID_v2017_08 "Drer\ehbp1l1b, Drer\actn3a, Drer\sptb, Drer\gas2l3, Drer\si:ch211-137a8.2, Drer\gas2b, Drer\LOC558044, Drer\syne3, Drer\actn4, Drer\gas2, Drer\spna2, Drer\actn1, Drer\actn2b, Drer\actn3b, Drer\ehbp1, Drer\pleca, Drer\sptbn1, Drer\zgc:165653" - "Cele\sma-1, Cele\atn-1" "Xtro\ehbp1l1, Xtro\actn4, Xtro\sptan1, Xtro\actn2, Xtro\sptbn2, Xtro\actn1, Xtro\sptbn5, Xtro\actn3, Xtro\ehbp1" "Mmus\Actn3, Mmus\Gas2, Mmus\Sptan1, Mmus\Actn4, Mmus\Plec, Mmus\Sptbn4, Mmus\Syne3, Mmus\Actn2, Mmus\Spta1, Mmus\Ehbp1l1, Mmus\Sptbn2, Mmus\Ehbp1, Mmus\Actn1, Mmus\Gas2l3, Mmus\Sptbn1" "Hsap\SPTAN1, Hsap\SPTBN1, Hsap\SPTBN2, Hsap\ACTN3, Hsap\GAS2L3, Hsap\SPTA1, Hsap\ACTN2, Hsap\GAS2, Hsap\ACTN4, Hsap\ACTN1, Hsap\SPTBN5, Hsap\EHBP1, Hsap\EHBP1L1, Hsap\SPTBN4, Hsap\SYNE3, Hsap\PLEC" " pupal stage | mid-late , embryonic stage -- adult stage , embryonic stage | mid-late " adult stage muscle cell

"viable,fertile,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,flightless,cold sensitive,flight defective,heat sensitive,female fertile,semidominant,hypoactive,small body,polyphasic,lethal - all die before end of embryonic stage,some die during embryonic stage,visible" "third instar larva,somatic muscle,muscle cell,myofibril,indirect flight muscle,sarcomere,actin filament bundle & egg chamber,ovariole,egg,germline clone,actin filament & follicle cell | somatic clone,eye,Z discMef2.PR,trichogen cell" DRSC25653 K -0.29073372 0.237851182 -0.186165933 -0.078904112 -0.639887683 1.942805924 FBgn0066345 l(3)99DEj lethal (3) 99DEj http://flybase.org/reports/FBgn0066345 gene - - - l(3)99DEj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267260 CR45696 - http://flybase.org/reports/FBgn0267260 non_protein_coding_gene - - - "lincRNA.169, CR45696" - CR45696 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086035 snoRNA:Me18S-G642 - http://flybase.org/reports/FBgn0086035 snoRNA_gene - - - "snoRNA:Me18S-G642, Me18S-Gm642, CR34664" - CR34664 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061091 l(3)S011302 lethal (3) S011302 http://flybase.org/reports/FBgn0061091 gene - - - "0113/02, l(3)S011302" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083738 Dje Dje http://flybase.org/reports/FBgn0083738 gene - - - Dje - - 11-Aug-17 DroID_v2017_08 - - - - - - immune response defective FBgn0034097 CG3687 - http://flybase.org/reports/FBgn0034097 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT22273, CG3687" - CG3687 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0261857 CR42786 - http://flybase.org/reports/FBgn0261857 pseudogene_attribute - - - "CR42786, lincRNA.821" - CR42786 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034300 CG5098 - http://flybase.org/reports/FBgn0034300 protein_coding_gene transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000383895 - - CG5098 IPR034732:Extended PHD (ePHD) domain CG5098 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165g14.1, Drer\tcf20, Drer\si:dkey-94l16.4, Drer\rai1" - Cele\F01D4.5 "Xtro\tcf20, Xtro\rai1" "Mmus\Tcf20, Mmus\Zfp957, Mmus\Rai1" "Hsap\AFF1, Hsap\RAI1, Hsap\TCF20" lethal FBgn0267216 CR45656 - http://flybase.org/reports/FBgn0267216 non_protein_coding_gene - - - CR45656 - CR45656 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029521 Or1a Odorant receptor 1a http://flybase.org/reports/FBgn0029521 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay olfactory behavior ; GO:0042048 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "1a, DOR68, 1A.1, CG17885, Or1a, OR1a" "IPR004117:Olfactory receptor, insect" CG17885 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC18689 I -2.188090806 0.167983671 -0.505942403 0.418849929 -0.231042621 -0.809183105 FBgn0082338 HM689 HM689 http://flybase.org/reports/FBgn0082338 gene - - - HM689 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053124 CG33124 - http://flybase.org/reports/FBgn0053124 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "CG10879, CG33124, CG33124-PB, dSLC5A13" IPR001734:Sodium/solute symporter CG33124 11-Aug-17 DroID_v2017_08 "Drer\slc5a8, Drer\slc5a6b, Drer\LOC568338, Drer\slc5a2, Drer\slc5a11, Drer\slc5a8l, Drer\slc5a9, Drer\slc5a1, Drer\slc5a3a, Drer\si:dkeyp-9d4.5, Drer\slc5a12, Drer\slc5a6a, Drer\slc5a5" Scer\DUR3 "Cele\F52H2.4, Cele\ZK822.5" "Xtro\slc5a12, Xtro\slc5a11, Xtro\slc5a2, Xtro\slc5a1.1, Xtro\slc5a9, Xtro\slc5a5, Xtro\slc5a8" "Mmus\Slc5a2, Mmus\Slc5a4a, Mmus\Slc5a10, Mmus\Slc5a1, Mmus\Slc5a8, Mmus\Slc5a9, Mmus\Slc5a12, Mmus\Slc5a5, Mmus\Slc5a4b, Mmus\Slc5a6, Mmus\Slc5a11, Mmus\Slc5a3, Mmus\Gm5134" "Hsap\SLC5A4, Hsap\SLC5A9, Hsap\SLC5A6, Hsap\SLC5A1, Hsap\SLC5A2, Hsap\SLC5A8, Hsap\SLC5A10, Hsap\SLC5A5, Hsap\SLC5A3, Hsap\SLC5A12, Hsap\SLC5A11" viable FBgn0024339 KHD-5 KH domain cDNA KHD-5 http://flybase.org/reports/FBgn0024339 - gene - - - KHD-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085313 CG34284 - http://flybase.org/reports/FBgn0085313 protein_coding_gene - - - CG34284 - CG34284 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264492 CkIIalpha casein kinase IIalpha http://flybase.org/reports/FBgn0264492 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with CkIIα-i1 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement" axon guidance ; GO:0007411 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype negative regulation of protein ubiquitination ; GO:0031397 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with fz inferred from genetic interaction with fz2 chaeta development ; GO:0022416 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype inferred from genetic interaction with orb positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from direct assay regulation of protein stability ; GO:0031647 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype intracellular mRNA localization involved in pattern specification process ; GO:0060810 | inferred from genetic interaction with CkIIβ cellular response to starvation ; GO:0009267 | inferred from expression pattern positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CK2, CkIIalpha, CKII alpha, CK2alpha, ck2alpha, CK2a, CKII, CKIIa, CG17520, CJIIalpha, dCK2alpha, CKIIalpha, alphaCK2, DmCK2alpha, CKIIalfa, dCKII, DmCKIIalpha, CK-II, CKII-alpha, Tik, CK II, CK2 alpha, CkII, CK-II alpha, CK-2, Cask-II-a, anon-WO02059370.53, dCKII alpha, Ck2alpha, CK2-alpha, ckIIalpha, 0958/08, l(3)S095808, Dm-CK2-alpha" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG17520 11-Aug-17 DroID_v2017_08 "Drer\csnk2a4, Drer\zgc:86598, Drer\csnk2a2b, Drer\csnk2a2a, Drer\csnk2a1" "Scer\CKA1, Scer\CKA2" "Cele\kin-3, Cele\cdk-2" "Xtro\csnk2a1, Xtro\csnk2a2" "Mmus\Csnk2a2, Mmus\Csnk2a1" "Hsap\CSNK2A3, Hsap\CSNK2A2, Hsap\CSNK2A1" FBgn0052755 CG32755 - http://flybase.org/reports/FBgn0052755 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - CG32755 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG32755 11-Aug-17 DroID_v2017_08 Drer\st14b - Cele\try-1 - Mmus\Klk6 Hsap\KLK6 viable FBgn0058233 CG40233 - http://flybase.org/reports/FBgn0058233 protein_coding_gene - - - CG40233 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011608 l(1)I32b6 lethal (1) I32b6 http://flybase.org/reports/FBgn0011608 FBgn0010206 gene - - - "l(1)I33b6, l(1)32b6, l(1)I32b6" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024991 CG2694 - http://flybase.org/reports/FBgn0024991 FBgn0024979 protein_coding_gene molecular_function ; GO:0003674 | no biological data available DNA demethylation ; GO:0080111 | inferred from biological aspect of ancestor with PANTHER:PTN000559411 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000559411 "EG:95B7.10, EG:100G10.8, CG2694" IPR006640:SprT-like CG2694 11-Aug-17 DroID_v2017_08 Drer\acrc Scer\FYV8 Cele\ZK328.4 - - Hsap\GCNA viable FBgn0003949 un uneven http://flybase.org/reports/FBgn0003949 - gene - - - "ro-63, un" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" "eye,wing,ommatidium,optic lobe,scutellum,scutellum & macrochaeta" FBgn0266331 CR44996 - http://flybase.org/reports/FBgn0266331 non_protein_coding_gene - - - CR44996 - CR44996 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037828 tomboy20 tomboy20 http://flybase.org/reports/FBgn0037828 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:Q15388 mitochondrion targeting sequence binding ; GO:0030943 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000277108 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 mitochondrial outer membrane translocase complex assembly ; GO:0070096 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q15388 tRNA import into mitochondrion ; GO:0016031 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 integral component of mitochondrial outer membrane ; GO:0031307 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from sequence or structural similarity with UniProtKB:Q15388 "CG14690, tomboy20" "IPR002056:Protein import receptor MAS20, IPR023392:Mitochondrial outer membrane translocase complex, subunit Tom20 domain, IPR022422:Protein import receptor MAS20, metazoan" CG14690 11-Aug-17 DroID_v2017_08 "Drer\tomm20a, Drer\tomm20b" Scer\TOM20 "Cele\F32B4.2, Cele\tomm-20" Xtro\tomm20 "Mmus\Tomm20l, Mmus\Tomm20" "Hsap\TOMM20L, Hsap\TOMM20" viable FBgn0032095 Toll-4 Toll-4 http://flybase.org/reports/FBgn0032095 protein_coding_gene single-stranded RNA binding ; GO:0003727 | inferred from electronic annotation with InterPro:IPR026880 transmembrane signaling receptor activity ; GO:0004888 | inferred from electronic annotation with InterPro:IPR026880 MyD88-dependent toll-like receptor signaling pathway ; GO:0002755 | inferred from electronic annotation with InterPro:IPR026880 defense response to virus ; GO:0051607 | inferred from electronic annotation with InterPro:IPR026880 toll-like receptor 7 signaling pathway ; GO:0034154 | inferred from electronic annotation with InterPro:IPR026880 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR026880 "dToll4, toll, dTLR4, TL4, CT29238, CG18241, Tl-4, Toll-4" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR000372:Leucine-rich repeat N-terminal domain, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR026880:Toll-like receptor 7" CG18241 11-Aug-17 DroID_v2017_08 "Drer\tlr2, Drer\LOC572462, Drer\tlr4bb, Drer\il1rapl1b, Drer\LOC100332783, Drer\il1rapl2, Drer\ncam1a, Drer\tlr7, Drer\tlr4ba, Drer\fgfr2, Drer\tlr5a, Drer\tlr22, Drer\zgc:101569, Drer\LOC799279, Drer\il1rapl1a, Drer\tlr9, Drer\tlr20.2, Drer\tlr18, Drer\tlr3, Drer\tlr21, Drer\LOC100332583, Drer\tlr1, Drer\cd180, Drer\tlr5b, Drer\LOC100005571, Drer\tlr8b" - Cele\tol-1 "Xtro\tlr2, Xtro\tlr9, Xtro\il1r2, Xtro\LOC100485512, Xtro\fgfr1, Xtro\LOC100485706, Xtro\tlr3, Xtro\tlr7, Xtro\LOC100485164, Xtro\tlr5, Xtro\fgfr3, Xtro\tlr6, Xtro\LOC100485201, Xtro\LOC100495326" "Mmus\Il1r2, Mmus\Tlr3, Mmus\Tlr6, Mmus\Tlr12, Mmus\Tlr7, Mmus\Tlr11, Mmus\Il1rl2, Mmus\Tlr5, Mmus\Il1rapl1, Mmus\Il1rap, Mmus\Tlr9, Mmus\Sigirr, Mmus\Cd180, Mmus\Il18rap, Mmus\Il18r1, Mmus\Il1rl1, Mmus\Tlr4, Mmus\Tlr1, Mmus\Fgfr1, Mmus\Il1r1, Mmus\Tlr8, Mmus\Tlr2, Mmus\Il1rapl2, Mmus\Tlr13" "Hsap\IL1R1, Hsap\IL1RAP, Hsap\IL18R1, Hsap\TLR8, Hsap\FGFR1, Hsap\TLR5, Hsap\TLR7, Hsap\TLR10, Hsap\TLR4, Hsap\TLR9, Hsap\TLR3, Hsap\SIGIRR, Hsap\IL18RAP, Hsap\IL1RL2, Hsap\TLR1, Hsap\TLR2, Hsap\IL1RAPL2, Hsap\CD180, Hsap\IL1RL1, Hsap\TLR6, Hsap\IL1R2, Hsap\IL1RAPL1" FBgn0060943 l(3)S039206b lethal (3) S039206b http://flybase.org/reports/FBgn0060943 gene - - - "0392/06, l(3)S039206b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001702 l(1)ESHS23 lethal (1) ESHS23 http://flybase.org/reports/FBgn0001702 - gene - - - l(1)ESHS23 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003636 su(ve) suppressor of veinlet http://flybase.org/reports/FBgn0003636 - gene - - - su(ve) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265856 CR44645 - http://flybase.org/reports/FBgn0265856 non_protein_coding_gene - - - CR44645 - CR44645 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264834 CR44042 - http://flybase.org/reports/FBgn0264834 non_protein_coding_gene - - - CR44042 - CR44042 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051117 CG31117 - http://flybase.org/reports/FBgn0051117 protein_coding_gene - - - CG31117 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024611 olf701 olfactory 701 http://flybase.org/reports/FBgn0024611 - gene - - - olf701 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005743 l(1)TK235 lethal (1) TK235 http://flybase.org/reports/FBgn0005743 - gene - - - "l235, l(1)TK235" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0065125 l(3)SH141 lethal (3) SH141 http://flybase.org/reports/FBgn0065125 gene - - - "l(3)SH141, l(2)SH3 141" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015943 furrow furrow http://flybase.org/reports/FBgn0015943 - gene - - - furrow - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265253 CR44267 - http://flybase.org/reports/FBgn0265253 non_protein_coding_gene - - - CR44267 - CR44267 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052558 CR32558 - http://flybase.org/reports/FBgn0052558 non_protein_coding_gene - - - CR32558 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041773 amanda amanda http://flybase.org/reports/FBgn0041773 gene - - - "amanda, ada" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,recessive,lethal,hyperplasia" "salivary gland,melanotic mass,embryonic/larval brain" FBgn0052817 CG32817 - http://flybase.org/reports/FBgn0052817 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32817 IPR022773:Siva CG32817 11-Aug-17 DroID_v2017_08 Drer\siva1 - - Xtro\siva1 Mmus\Siva1 Hsap\SIVA1 FBgn0001777 l(1)M58 lethal (1) M58 http://flybase.org/reports/FBgn0001777 - gene - - - l(1)M58 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "macrochaeta,wing" FBgn0085431 CG34402 - http://flybase.org/reports/FBgn0085431 protein_coding_gene - - - "CG34402, CG17793, CG31218, SOL-1, sol-1, CT39356, CG17756, CG4940" IPR000859:CUB domain CG34402 11-Aug-17 DroID_v2017_08 "Drer\si:cabz01033205.3, Drer\pcolceb" - Cele\sol-1 - - - DRSC15681 K 0.472735568 -0.456273087 -0.248648253 -0.096946189 -1.745926199 0.466052849 FBgn0084245 tre-3 tre-3 http://flybase.org/reports/FBgn0084245 - - - - "tre-3, CG34647, CR34647" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025133 su(RpII140[Z36])S14 su(RpII140[Z36])S14 http://flybase.org/reports/FBgn0025133 - gene - - - "Z36[S14], su(RpII140[Z36])S14" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064178 l(1)B.8 lethal (1) B.8 http://flybase.org/reports/FBgn0064178 gene - - - l(1)B.8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032111 CG13110 - http://flybase.org/reports/FBgn0032111 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "BcDNA:AT19071, CG13110" - CG13110 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264394 CR43842 - http://flybase.org/reports/FBgn0264394 non_protein_coding_gene - - - CR43842 - CR43842 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000503 dss disturbed segmentation http://flybase.org/reports/FBgn0000503 - gene - - - dss - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,visible,viable,male,poor,female sterile,body color defective" "adult abdomen,adult abdomen & microchaeta,macrochaeta,eye" FBgn0030133 CG15316 - http://flybase.org/reports/FBgn0030133 protein_coding_gene - - - CG15316 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053502 CG33502 - http://flybase.org/reports/FBgn0053502 protein_coding_gene molecular_function ; GO:0003674 | no biological data available iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR001075 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001075 "biological_process ; GO:0008150 | no biological data available iron-sulfur cluster assembly ; GO:0016226 | inferred from electronic annotation with InterPro:IPR001075, InterPro:IPR017065" cellular_component ; GO:0005575 | no biological data available "BcDNA:GM32035, CG18856, CG33502" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR014824:Scaffold protein Nfu/NifU, N-terminal, IPR001075:NIF system FeS cluster assembly, NifU, C-terminal, IPR017065:NFU1 iron-sulfur cluster scaffold homologue" CG33502 11-Aug-17 DroID_v2017_08 "Drer\nfu1, Drer\zgc:110319" Scer\NFU1 Cele\lpd-8 Xtro\nfu1 Mmus\Nfu1 Hsap\NFU1 FBgn0004529 l(4)102CDk lethal (4) 102CDk http://flybase.org/reports/FBgn0004529 - gene - - - "l(4)ST-1, l(4)21, l(4)102CDk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033377 Pmm45A Phosphomannomutase 45A http://flybase.org/reports/FBgn0033377 protein_coding_gene "intramolecular transferase activity, phosphotransferases ; GO:0016868 | inferred from electronic annotation with InterPro:IPR005841, InterPro:IPR005843, InterPro:IPR005844, InterPro:IPR005846, InterPro:IPR016055 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR016066" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR005841, InterPro:IPR005844, InterPro:IPR005845, InterPro:IPR005846, InterPro:IPR016055" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000501326 "CG8073, Pmm45A" "IPR005841:Alpha-D-phosphohexomutase superfamily, IPR005844:Alpha-D-phosphohexomutase, alpha/beta/alpha domain I, IPR005845:Alpha-D-phosphohexomutase, alpha/beta/alpha domain II, IPR016055:Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III, IPR016066:Alpha-D-phosphohexomutase, conserved site, IPR005843:Alpha-D-phosphohexomutase, C-terminal, IPR005846:Alpha-D-phosphohexomutase, alpha/beta/alpha domain III" CG8073 11-Aug-17 DroID_v2017_08 "Drer\pgm2l1, Drer\pgm2" Scer\PRM15 Cele\Y43F4B.5 "Xtro\pgm2, Xtro\pgm2l1" "Mmus\Pgm2l1, Mmus\Pgm1" "Hsap\PGM2L1, Hsap\PGM2" viable FBgn0016639 ER2-3 ER2-3 http://flybase.org/reports/FBgn0016639 - gene - - - ER2-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036232 CG14125 - http://flybase.org/reports/FBgn0036232 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14125 "IPR002557:Chitin binding domain, IPR006970:PT repeat" CG14125 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030927 CG15046 - http://flybase.org/reports/FBgn0030927 protein_coding_gene - - - CG15046 "IPR009003:Peptidase S1, PA clan, IPR022700:Proteinase, regulatory CLIP domain" CG15046 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039552 CG12426 - http://flybase.org/reports/FBgn0039552 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12426 - CG12426 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0001752 l(1)J1024 lethal (1) J1024 http://flybase.org/reports/FBgn0001752 - gene - - - l(1)J1024 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" "spermatid,testis" FBgn0010175 RpA-8 Replication Protein A 8 http://flybase.org/reports/FBgn0010175 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay DNA-dependent DNA replication ; GO:0006261 | inferred from direct assay DNA replication factor A complex ; GO:0005662 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DmRPA, RPA, RP-A, dRP-A, DRP-A, D-SSB, Ssb-8, RpA-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage FBgn0029948 CheA7a Chemosensory protein A 7a http://flybase.org/reports/FBgn0029948 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheA29a extracellular region ; GO:0005576 | inferred from sequence model "CG15033, CheA7a" IPR010512:Protein of unknown function DUF1091 CG15033 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0265583 CR44410 - http://flybase.org/reports/FBgn0265583 non_protein_coding_gene - - - CR44410 - CR44410 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000110 apx apexless http://flybase.org/reports/FBgn0000110 - gene - - - apx - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,male fertile,female fertile,reduced,female sterile,partially" "eye,ommatidium,wing,wing vein L1,wing vein L4,wing vein L5,costal vein,wing vein L3" FBgn0020222 Chr2 Chloroform resistant 2 http://flybase.org/reports/FBgn0020222 - gene - - - Chr2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,maternal effect,semidominant" FBgn0034731 CG10384 - http://flybase.org/reports/FBgn0034731 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 - - "cg10384, CG10384" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG10384 11-Aug-17 DroID_v2017_08 "Drer\qkib, Drer\qkia, Drer\khdrbs2, Drer\khdrbs3, Drer\khdrbs1b, Drer\qki2, Drer\khdrbs1a" Scer\MSL5 Cele\asd-2 "Xtro\khdrbs3, Xtro\qki, Xtro\khdrbs2, Xtro\khdrbs1" "Mmus\Khdrbs2, Mmus\Khdrbs3, Mmus\Khdrbs1, Mmus\Qk" "Hsap\QKI, Hsap\KHDRBS2, Hsap\KHDRBS3, Hsap\KHDRBS1" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0033366 Ance-4 Ance-4 http://flybase.org/reports/FBgn0033366 protein_coding_gene peptidyl-dipeptidase activity ; GO:0008241 | inferred from electronic annotation with InterPro:IPR001548 metallopeptidase activity ; GO:0008237 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001548 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001548 "CG8196, Ance-4, ance-4" "IPR001548:Peptidase M2, peptidyl-dipeptidase A" CG8196 11-Aug-17 DroID_v2017_08 "Drer\ace, Drer\ace2, Drer\si:dkey-194e6.1" - Cele\acn-1 "Xtro\tmem27, Xtro\ace2, Xtro\ace" "Mmus\Ace, Mmus\Ace3, Mmus\Tmem27, Mmus\Ace2" "Hsap\ACE, Hsap\ACE2, Hsap\TMEM27" "viable,visible" mesothoracic tergum FBgn0065502 l(2)SH1205 lethal (2) SH1205 http://flybase.org/reports/FBgn0065502 gene - - - "l(2)SH1205, l(2)SH2 1205" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036158 CG6149 - http://flybase.org/reports/FBgn0036158 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006838 CG6149 IPR006838:FAR-17a/AIG1-like protein CG6149 11-Aug-17 DroID_v2017_08 "Drer\LOC100537455, Drer\zgc:112175, Drer\mybl2a, Drer\aig1" Scer\YHR140W "Cele\cTel55X.1, Cele\C37E2.2, Cele\C37E2.3" Xtro\myo15a "Mmus\Aig1, Mmus\Adtrp" "Hsap\ADTRP, Hsap\AIG1" viable FBgn0067377 l(2)NC114 lethal (2) NC114 http://flybase.org/reports/FBgn0067377 gene - - - l(2)NC114 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0054052 CR34052 - http://flybase.org/reports/FBgn0054052 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1069, CG34052, CR34052" - CR34052 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003443 small-narrow small narrow http://flybase.org/reports/FBgn0003443 - gene - - - "small-narrow, smn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,poor,male sterile,visible" "adult abdomen,wing" FBgn0265804 CR44593 - http://flybase.org/reports/FBgn0265804 non_protein_coding_gene - - - "CR44593, Mgn00375, Mgn00376" - CR44593 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038016 MBD-R2 MBD-R2 http://flybase.org/reports/FBgn0038016 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001739, InterPro:IPR016177 promoter-specific chromatin binding ; GO:1990841 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q86BS3,UniProtKB:Q9VCH5,UniProtKB:Q9VP57" neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay NSL complex ; GO:0044545 | inferred from direct assay "dMBD-R2, TAM3, Dm Tam3, CG10042, MBD, CG17393, MBD-R2, MBDR2, mbd-R2, Mbdr2, Mbrd2, MBD-R2/NSL" "IPR001739:Methyl-CpG DNA binding, IPR006612:Zinc finger, C2CH-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR016177:DNA-binding domain, IPR019786:Zinc finger, PHD-type, conserved site, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR002999:Tudor domain" CG10042 11-Aug-17 DroID_v2017_08 "Drer\phf3, Drer\kmt2d, Drer\whsc1, Drer\phf20a, Drer\setd1ba, Drer\kmt2e, Drer\nsd1b, Drer\phf20b, Drer\phf20l1, Drer\ash1l, Drer\whsc1l1" "Scer\CTI6, Scer\SET3, Scer\SET2, Scer\BYE1, Scer\SET4, Scer\SET1" "Cele\mes-4, Cele\set-9, Cele\set-12, Cele\set-26, Cele\lin-59, Cele\set-16, Cele\C16A11.4, Cele\set-5, Cele\met-1" "Xtro\mbd4, Xtro\phf20, Xtro\phf20l1, Xtro\setd1b, Xtro\kmt2e" "Mmus\Setd1b, Mmus\Setd2, Mmus\Whsc1, Mmus\Phf3, Mmus\Mbd3, Mmus\Phf20, Mmus\Dido1, Mmus\Kmt2e, Mmus\Mbd3l2, Mmus\Setd5, Mmus\Kmt2d, Mmus\Spocd1, Mmus\Nsd1, Mmus\Ash1l, Mmus\Mbd3l1, Mmus\Kmt2c, Mmus\Mbd4, Mmus\Phf13, Mmus\Mecp2, Mmus\Phf20l1, Mmus\Whsc1l1, Mmus\Setd1a" "Hsap\WHSC1, Hsap\PHF20, Hsap\ASH1L, Hsap\MBD3L5, Hsap\PHF20L1, Hsap\SETD1A, Hsap\MECP2, Hsap\DIDO1, Hsap\MBD4, Hsap\KMT2E, Hsap\KMT2C, Hsap\SETD5, Hsap\MBD3L4, Hsap\NSD1, Hsap\KMT2D, Hsap\MBD3L3, Hsap\SETD1B, Hsap\MBD3L2, Hsap\WHSC1L1, Hsap\SETD2, Hsap\MBD3L1" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC14180 E -1.185644906 -1.363071689 0.127676691 -4.337460815 -0.266085184 -0.813038192 FBgn0060801 l(3)S057115b lethal (3) S057115b http://flybase.org/reports/FBgn0060801 gene - - - "0571/15, l(3)S057115b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0060626 l(3)S087217b lethal (3) S087217b http://flybase.org/reports/FBgn0060626 gene - - - "0872/17, l(3)S087217b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0020358 anon-28Aa anon-28Aa http://flybase.org/reports/FBgn0020358 - gene - - - "551, anon-28Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262143 CG42869 - http://flybase.org/reports/FBgn0262143 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42869 - CG42869 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259300 C388 - http://flybase.org/reports/FBgn0259300 gene - - - C388 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing,chaeta" FBgn0050199 tRNA:Ala-CGC-1-2 transfer RNA:Alanine-CGC 1-2 http://flybase.org/reports/FBgn0050199 tRNA_gene GCG codon-amino acid adaptor activity ; GO:0033456 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033456 cytosol ; GO:0005829 | inferred by curator from GO:0033456 "CR30199, AE002575.trna7-AlaCGC, tRNA:A:CGC:AE002575-b, tRNA[[Ala]], chr2R.trna51-AlaCGC, tRNA-Ala-CGC-1-2, tRNA:Ala-CGC-1-2, tRNA:CR30199, GCG" - CR30199 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060606 l(3)S090613b lethal (3) S090613b http://flybase.org/reports/FBgn0060606 gene - - - "0906/13, l(3)S090613b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033067 CG11211 - http://flybase.org/reports/FBgn0033067 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - "BcDNA:RH26557, CG11211" "IPR001304:C-type lectin-like, IPR018378:C-type lectin, conserved site, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG11211 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-125e6.13, Drer\si:ch211-125e6.12, Drer\si:dkey-9i23.4, Drer\si:dkey-241l7.6, Drer\si:dkey-216e24.3, Drer\si:dkeyp-75b4.10, Drer\si:dkey-9i23.5, Drer\si:dkey-241l7.5, Drer\si:ch211-125e6.5, Drer\si:dkey-241l7.2, Drer\zgc:172053, Drer\si:ch211-170d8.5, Drer\si:dkey-241l7.3, Drer\si:ch211-125e6.11, Drer\clec19a" - "Cele\clec-26, Cele\clec-4, Cele\clec-49, Cele\clec-50, Cele\clec-39, Cele\clec-187, Cele\clec-17, Cele\clec-31, Cele\clec-83, Cele\clec-9, Cele\clec-38, Cele\clec-48, Cele\clec-7" "Xtro\clec3b, Xtro\clec3a" Mmus\Pla2r1 "Hsap\PLA2R1, Hsap\COLEC11" "viable,fertile" FBgn0015401 kni::knrl kni::knrl http://flybase.org/reports/FBgn0015401 - engineered_fusion_gene - - - kni::knrl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264839 CR44047 - http://flybase.org/reports/FBgn0264839 non_protein_coding_gene - - - CR44047 - CR44047 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053554 Nipped-A Nipped-A http://flybase.org/reports/FBgn0053554 protein_coding_gene kinase activity ; GO:0016301 | inferred from electronic annotation with InterPro:IPR000403 histone acetyltransferase activity ; GO:0004402 | inferred from direct assay contributes_to histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay "mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from direct assay transcription, DNA-templated ; GO:0006351 | inferred from direct assay positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with mam inferred from genetic interaction with N phagocytosis ; GO:0006909 | inferred from mutant phenotype wing disc pattern formation ; GO:0035222 | inferred from genetic interaction with mam inferred from genetic interaction with N histone exchange ; GO:0043486 | inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont microtubule associated complex ; GO:0005875 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "dTra1, dmTRRAP, TRRAP, CG2905, tra1, 41Ah, Nipped[A], l(2)41Ah, l(2)EMS34-12, GroupV, Tra-1, CG33554, l(2)C123, CG10549, Tra1, Nipped-A, NipA, Nip-A, dTRRAP, Nipped A, TRA1" "IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR003151:PIK-related kinase, FAT, IPR003152:FATC domain, IPR014009:PIK-related kinase, IPR016024:Armadillo-type fold, IPR011009:Protein kinase-like domain, IPR011989:Armadillo-like helical, IPR033317:Transcription-associated protein 1, IPR011990:Tetratricopeptide-like helical domain" CG33554 11-Aug-17 DroID_v2017_08 Drer\trrap Scer\TRA1 Cele\trr-1 Xtro\trrap Mmus\Trrap Hsap\TRRAP "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,lethal,partially,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,increased cell death" "wing,ocellus,embryonic/larval neuroblast,ganglion mother cell,embryonic/larval brain,trichogen cell,mesothoracic tergum,imaginal disc" DRSC22386 IEK -2.471628354 -2.510615658 -3.383750856 -5.756960909 2.561044333 1.76685858 FBgn0037282 CG14657 - http://flybase.org/reports/FBgn0037282 protein_coding_gene - - - CG14657 - CG14657 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036826 arx asterix http://flybase.org/reports/FBgn0036826 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype gene silencing by RNA ; GO:0031047 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "BcDNA:LD18018, CG3893, Gtsf1, DmGTSF1, arx, gtsf1" "IPR013087:Zinc finger C2H2-type, IPR022776:TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG3893 11-Aug-17 DroID_v2017_08 "Drer\LOC100535654, Drer\zgc:56699" - Cele\T06A10.3 "Xtro\gtsf1, Xtro\LOC100145274" "Mmus\Zfp850, Mmus\Gtsf1l, Mmus\Gtsf1, Mmus\BC048502" "Hsap\GTSF1L, Hsap\GTSF1" "viable,female sterile,male fertile,female fertile" "ovary,polar follicle cell,oocyte" FBgn0026172 slow-phase slow phase http://flybase.org/reports/FBgn0026172 - gene - - - "sph, slow-phase" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265793 CR44582 - http://flybase.org/reports/FBgn0265793 non_protein_coding_gene - - - CR44582 - CR44582 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030157 CG1468 - http://flybase.org/reports/FBgn0030157 protein_coding_gene - - - "BcDNA:GH18955, CG1468" - CG1468 11-Aug-17 DroID_v2017_08 - - Cele\clec-186 - - - FBgn0266567 E(spl)mgamma-HLH::E(spl)mdelta-HLH - http://flybase.org/reports/FBgn0266567 engineered_fusion_gene - - - E(spl)mgamma-HLH::E(spl)mdelta-HLH - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "chaeta,mesothoracic tergum" FBgn0033888 CG18568 - http://flybase.org/reports/FBgn0033888 protein_coding_gene - - - "anon-WO0140519.113, CG18568" - CG18568 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005445 l(1)v163 lethal (1) v163 http://flybase.org/reports/FBgn0005445 - gene - - - "l(1)163, l(1)v163" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016020 l(3)843 lethal (3) 843 http://flybase.org/reports/FBgn0016020 - gene - - - l(3)843 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062600 Mod(var)1457 Mod(var)1457 http://flybase.org/reports/FBgn0062600 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1457, Mod(var)1457" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0011932 tRNA:Asn-GTT-1-5 transfer RNA:Asparagine-GTT 1-5 http://flybase.org/reports/FBgn0011932 "FBgn0003759, FBgn0050308, FBgn0050511" tRNA_gene - - - "asn-tRNA, tRNA:asn5:42Ab, CR30308, CR30511, chr2R.trna4-AsnGTT, tRNA-Asn-GTT-1-5, tRNA:Asn-GTT-1-5, tRNA:N5:42Ab, AAC" - CR30511 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037676 CG8861 - http://flybase.org/reports/FBgn0037676 protein_coding_gene - - - CG8861 - CG8861 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030263 CG2076 - http://flybase.org/reports/FBgn0030263 protein_coding_gene - - - CG2076 IPR006214:Bax inhibitor 1-related CG2076 11-Aug-17 DroID_v2017_08 Drer\ghitm - Cele\K11H12.8 Xtro\ghitm Mmus\Ghitm Hsap\GHITM "viable,fertile" FBgn0002580 M(1)3E Minute (1) 3E http://flybase.org/reports/FBgn0002580 - gene - - - M(1)3E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034438 CG9416 - http://flybase.org/reports/FBgn0034438 protein_coding_gene - - - "CG9416, CG9416-PA" IPR007484:Peptidase M28 CG9416 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\VPS70, Scer\YDR415C, Scer\PFF1, Scer\APE3" "Cele\C44B7.11, Cele\B0495.7" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0267773 CR46104 - http://flybase.org/reports/FBgn0267773 non_protein_coding_gene - - - CR46104 - CR46104 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034894 sigmar salivary glands marred http://flybase.org/reports/FBgn0034894 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR013785 cysteine-type endopeptidase inhibitor activity involved in apoptotic process ; GO:0043027 | inferred from sequence or structural similarity with UniProtKB:O95379 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern regulation of autophagy ; GO:0010506 | inferred from mutant phenotype regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from mutant phenotype cell projection ; GO:0042995 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:O95379 "CG4091, sigmar" "IPR008477:Protein of unknown function DUF758, IPR013785:Aldolase-type TIM barrel" CG4091 11-Aug-17 DroID_v2017_08 "Drer\tnfaip8l2b, Drer\tnfaip8l1, Drer\tnfaip8l3, Drer\tnfaip8l2a" - Cele\sdz-15 "Xtro\tnfaip8l2, Xtro\tnfaip8, Xtro\tnfaip8l3" "Mmus\Tnfaip8l1, Mmus\Tnfaip8, Mmus\Tnfaip8l3, Mmus\Tnfaip8l2" "Hsap\TNFAIP8L2, Hsap\TNFAIP8, Hsap\TNFAIP8L3, Hsap\TNFAIP8L1" "lethal,viable,fertile,visible" trichogen cell FBgn0065382 l(2)SH1663 lethal (2) SH1663 http://flybase.org/reports/FBgn0065382 gene - - - "l(2)SH1663, l(2)SH2 1663" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084333 LA00007 LA00007 http://flybase.org/reports/FBgn0084333 gene - - - LA00007 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050479 CG30479 - http://flybase.org/reports/FBgn0050479 protein_coding_gene - - - "CG18373, CG30479" - CG30479 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028137 l(3)S049217d lethal (3) S049217d http://flybase.org/reports/FBgn0028137 gene - - - "0492/17, l(3)S049217, l(3)S049217d" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0051769 CG31769 - http://flybase.org/reports/FBgn0051769 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RH26533, CG31769" - CG31769 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259861 Su(Ste):CR42430 Su(Ste):CR42430 http://flybase.org/reports/FBgn0259861 non_protein_coding_gene - - - "Su(Ste):CR42430, SuSte{}RR42320, CR42430" - CR42430 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067771 fried fried http://flybase.org/reports/FBgn0067771 gene molecular_function ; GO:0003674 | no biological data available karyosome formation ; GO:0030717 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fried - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone,karyosome,nurse cell & nucleus | germ-line clone" FBgn0060438 l(3)S125006b lethal (3) S125006b http://flybase.org/reports/FBgn0060438 gene - - - "1250/06, l(3)S125006b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0060454 l(3)S119016b lethal (3) S119016b http://flybase.org/reports/FBgn0060454 gene - - - "1190/16, l(3)S119016b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0029143 P(3)91A P(3)91A http://flybase.org/reports/FBgn0029143 gene - - - P(3)91A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267894 CR46182 - http://flybase.org/reports/FBgn0267894 pseudogene_attribute - - - "CR46182, CG12717-related" - CR46182 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067746 l(1)G0256 lethal (1) G0256 http://flybase.org/reports/FBgn0067746 gene - - - l(1)G0256 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0012036 Aldh Aldehyde dehydrogenase http://flybase.org/reports/FBgn0012036 FBgn0032114 protein_coding_gene acetaldehyde dehydrogenase (acetylating) activity ; GO:0008774 | inferred from direct assay aldehyde dehydrogenase (NAD) activity ; GO:0004029 | inferred from sequence or structural similarity with UniProtKB:P05091 aldehyde dehydrogenase (NAD) activity ; GO:0004029 | inferred from direct assay "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016160, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163, InterPro:IPR029510 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:P05091 response to ethanol ; GO:0045471 | inferred from mutant phenotype acetaldehyde metabolic process ; GO:0006117 | inferred from mutant phenotype negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P05091 lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "ALDH, Aldh, 146084_at, CG3752, ACDH, CG 3752, ALDHA1" "IPR015590:Aldehyde dehydrogenase domain, IPR016160:Aldehyde dehydrogenase, cysteine active site, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR029510:Aldehyde dehydrogenase, glutamic acid active site" CG3752 11-Aug-17 DroID_v2017_08 "Drer\aldh1l2, Drer\aldh1a3, Drer\aldh9a1b, Drer\aldh9a1a.1, Drer\aldh2.1, Drer\aldh1a2, Drer\wu:fb14d09, Drer\aldh16a1, Drer\aldh2.2, Drer\aldh8a1, Drer\aldh1l1" "Scer\MSC7, Scer\ALD2, Scer\ALD5, Scer\ALD3, Scer\ALD6, Scer\ALD4" "Cele\alh-11, Cele\alh-1, Cele\alh-3, Cele\alh-2, Cele\alh-10" "Xtro\aldh1a1, Xtro\aldh9a1, Xtro\aldh1a2, Xtro\aldh1b1, Xtro\aldh16a1, Xtro\aldh1a3, Xtro\aldh1l2, Xtro\aldh2, Xtro\aldh1l1" "Mmus\Aldh16a1, Mmus\Aldh1b1, Mmus\Aldh8a1, Mmus\Aldh1a3, Mmus\Aldh1a7, Mmus\Aldh1a2, Mmus\Aldh2, Mmus\Aldh1l1, Mmus\Aldh9a1, Mmus\Aldh1l2, Mmus\Aldh1a1" "Hsap\ALDH1A3, Hsap\ALDH1A1, Hsap\ALDH16A1, Hsap\ALDH1L1, Hsap\ALDH8A1, Hsap\ALDH9A1, Hsap\ALDH1A2, Hsap\ALDH1L2, Hsap\ALDH2, Hsap\ALDH1B1" "viable,chemical sensitive,starvation stress response defective,oxidative stress response defective,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0010148 l(3)96Ff lethal (3) 96Ff http://flybase.org/reports/FBgn0010148 - gene - - - l(3)96Ff - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014225 l(2)31Ed lethal (2) 31Ed http://flybase.org/reports/FBgn0014225 - gene - - - l(2)31Ed - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037193 CG17812 - http://flybase.org/reports/FBgn0037193 protein_coding_gene - - - CG17812 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263528 mir-4970 mir-4970 stem loop http://flybase.org/reports/FBgn0263528 miRNA_gene - - - "mir-4970, dme-mir-4970, CR43513" - CR43513 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037709 CG8199 - http://flybase.org/reports/FBgn0037709 protein_coding_gene alpha-ketoacid dehydrogenase activity ; GO:0003826 | inferred from electronic annotation with InterPro:IPR034616 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity ; GO:0003863 | inferred from sequence or structural similarity with UniProtKB:P12694 branched-chain amino acid catabolic process ; GO:0009083 | inferred from electronic annotation with InterPro:IPR034616 fatty-acyl-CoA biosynthetic process ; GO:0046949 | inferred from sequence or structural similarity with UniProtKB:P12694 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex ; GO:0017086 | inferred from sequence or structural similarity with UniProtKB:P12694 CG8199 "IPR001017:Dehydrogenase, E1 component, IPR034616:2-oxoisovalerate dehydrogenase subunit alpha, IPR029061:Thiamin diphosphate-binding fold" CG8199 11-Aug-17 DroID_v2017_08 Drer\bckdha Scer\PDA1 "Cele\Y39E4A.3, Cele\Y43F4A.4" Xtro\bckdha Mmus\Bckdha "Hsap\TMEM91, Hsap\BCKDHA" viable FBgn0020287 l(3)02693 lethal (3) 02693 http://flybase.org/reports/FBgn0020287 - gene - - - l(3)02693 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266475 cacahuete - http://flybase.org/reports/FBgn0266475 gene - - - cacahuete - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "egg chamber,germline clone,oocyte,ring canal" FBgn0266774 CR45239 - http://flybase.org/reports/FBgn0266774 non_protein_coding_gene - - - CR45239 - CR45239 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067039 XG47 XG47 http://flybase.org/reports/FBgn0067039 gene molecular_function ; GO:0003674 | no biological data available wing disc development ; GO:0035220 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available XG47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable" wing FBgn0004520 l(4)102CDd lethal (4) 102CDd http://flybase.org/reports/FBgn0004520 - gene - - - "l(4)5, l(4)102CDd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032907 CG9272 - http://flybase.org/reports/FBgn0032907 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000445 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR003651 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity ; GO:0000703 | inferred from biological aspect of ancestor with PANTHER:PTN000040498" "cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype base-excision repair, AP site formation ; GO:0006285 | inferred from biological aspect of ancestor with PANTHER:PTN000040498 nucleotide-excision repair, DNA incision, 5'-to lesion ; GO:0006296 | inferred from biological aspect of ancestor with PANTHER:PTN000040498" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000040500 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000040501 "CG9272, 9272" "IPR003265:HhH-GPD domain, IPR003651:Endonuclease III-like, iron-sulphur cluster loop motif, IPR004036:Endonuclease III-like, conserved site-2, IPR011257:DNA glycosylase, IPR030841:Endonuclease III-like protein 1, IPR000445:Helix-hairpin-helix motif, IPR023170:Helix-turn-helix, base-excision DNA repair, C-terminal" CG9272 11-Aug-17 DroID_v2017_08 Drer\nthl1 "Scer\NTG2, Scer\NTG1" Cele\nth-1 Xtro\nthl1 Mmus\Nthl1 Hsap\NTHL1 viable FBgn0001924 l(2)25Ce lethal (2) 25Ce http://flybase.org/reports/FBgn0001924 - gene - - - "jf19, l(2)jf19, l(2)25Ce" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010788 l(3)02733 lethal (3) 02733 http://flybase.org/reports/FBgn0010788 - gene - - - l(3)02733 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267072 CR45516 - http://flybase.org/reports/FBgn0267072 non_protein_coding_gene - - - CR45516 - CR45516 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085593 CG41277 - http://flybase.org/reports/FBgn0085593 protein_coding_gene - - - CG41277 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259535 B2007 - http://flybase.org/reports/FBgn0259535 gene - - - B2007 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,leg,wing,arista,third segment of antenna" FBgn0003069 pers persimmon http://flybase.org/reports/FBgn0003069 - gene - - - pers - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,eye color defective" "pigment cell,Malpighian tubule" FBgn0069187 l(3)c00213 lethal (3) c00213 http://flybase.org/reports/FBgn0069187 gene - - - l(3)c00213 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267900 CR46188 - http://flybase.org/reports/FBgn0267900 pseudogene_attribute - - - "CR46188, CG12717-related" - CR46188 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016845 l(1)N23 lethal (1) N23 http://flybase.org/reports/FBgn0016845 - gene - - - "l(1)N23, N23" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053335 CG33335 - http://flybase.org/reports/FBgn0053335 protein_coding_gene - - - CG33335 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043982 Su(rst)E392 Su(rst)E392 http://flybase.org/reports/FBgn0043982 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E392, Su(rst)E392" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037809 CG12818 - http://flybase.org/reports/FBgn0037809 protein_coding_gene molecular_function ; GO:0003674 | no biological data available lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG12818 "IPR019339:CBF1-interacting co-repressor CIR, N-terminal domain" CG12818 11-Aug-17 DroID_v2017_08 Drer\leng1 - Cele\Y18H1A.2 Xtro\leng1 Mmus\Leng1 Hsap\LENG1 "viable,visible" "chaeta,supernumerary" FBgn0065363 l(2)SH1725 lethal (2) SH1725 http://flybase.org/reports/FBgn0065363 gene - - - "l(2)SH1725, l(2)SH2 1725" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266867 CR45328 - http://flybase.org/reports/FBgn0266867 non_protein_coding_gene - - - CR45328 - CR45328 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260986 mei-38 meiotic 38 http://flybase.org/reports/FBgn0260986 protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay microtubule bundle formation ; GO:0001578 | inferred from direct assay meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype homologous chromosome segregation ; GO:0045143 | inferred from mutant phenotype distributive segregation ; GO:0032837 | inferred from mutant phenotype inferred from genetic interaction with mei-218 mitotic spindle ; GO:0072686 | colocalizes_with inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay polar microtubule ; GO:0005827 | inferred from direct assay spindle midzone ; GO:0051233 | NOT inferred from direct assay spindle ; GO:0005819 | colocalizes_with inferred from direct assay "mei-38, EG:80H7.11, ssp1, CG14781, Ssp1, Mei-38, D-TPX2, rush-3'utr" - CG14781 11-Aug-17 DroID_v2017_08 Drer\tpx2 - Cele\ZK1053.3 - Mmus\Tpx2 Hsap\TPX2 "spindle microtubule & oocyte,spindle pole & oocyte,karyosome & oocyte,spindle microtubule & larval brain,spindle pole & larval brain" FBgn0083053 snoRNA:Psi18S-1347b snoRNA:Psi18S-1347b http://flybase.org/reports/FBgn0083053 snoRNA_gene - - - "snoRNA:Psi18S-1347b, Psi18S-1347b, psi18S-1347b, CR34545, chr2R:13657839..13657931" - CR34545 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031039 Shawn Shawn http://flybase.org/reports/FBgn0031039 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from sequence model mitochondrial transmembrane transport ; GO:1990542 | inferred from sequence model metal ion homeostasis ; GO:0055065 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "CG33075, CG14209, Shawn, sh" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG14209 11-Aug-17 DroID_v2017_08 "Drer\slc25a40, Drer\slc25a39" Scer\MTM1 Cele\C16C10.1 "Xtro\slc25a40, Xtro\slc25a39" "Mmus\Slc25a39, Mmus\Slc25a40" "Hsap\SLC25A39, Hsap\SLC25A40" FBgn0265272 CG30060 - http://flybase.org/reports/FBgn0265272 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG30060, anon-SAGE:Wang-129" IPR008914:Phosphatidylethanolamine-binding protein CG30060 11-Aug-17 DroID_v2017_08 "Drer\atp10b, Drer\atp8b5a, Drer\atp11a, Drer\atp8a1, Drer\atp11c, Drer\atp8b3, Drer\atp8b5b, Drer\pebp1, Drer\atp8b4" "Scer\YLR179C, Scer\DNF1, Scer\TFS1, Scer\DNF2, Scer\MRPL35, Scer\DRS2" "Cele\Y69E1A.5, Cele\F40A3.3" "Xtro\atp11a, Xtro\atp8b4, Xtro\atp11c, Xtro\atp10a, Xtro\atp8b1, Xtro\LOC100490503, Xtro\atp11b, Xtro\atp10d, Xtro\pebp4, Xtro\pebp1" "Mmus\Atp11b, Mmus\Pbp2, Mmus\Atp8b3, Mmus\Atp10b, Mmus\Pebp1, Mmus\Atp11c, Mmus\Atp11a, Mmus\Atp10a, Mmus\Pebp4, Mmus\Atp8b5, Mmus\Atp8b2" "Hsap\ATP8B2, Hsap\ATP10A, Hsap\PEBP4, Hsap\PEBP1, Hsap\ATP11B, Hsap\ATP10B, Hsap\ATP11C, Hsap\ATP10D, Hsap\ATP8B4, Hsap\ATP11A" FBgn0058396 CG40396 - http://flybase.org/reports/FBgn0058396 protein_coding_gene - - - "BcDNA:AT30578, CG40396" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21812 IE 0.549685848 -1.945275937 0.04330481 2.288341993 0.540464787 -0.091829053 FBgn0027493 AdSS Adenylosuccinate Synthetase http://flybase.org/reports/FBgn0027493 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001114, InterPro:IPR018220 adenylosuccinate synthase activity ; GO:0004019 | inferred from biological aspect of ancestor with PANTHER:PTN000217844" neurogenesis ; GO:0022008 | inferred from mutant phenotype 'de novo' AMP biosynthetic process ; GO:0044208 | inferred from biological aspect of ancestor with PANTHER:PTN000217844 IMP metabolic process ; GO:0046040 | inferred from biological aspect of ancestor with PANTHER:PTN000217844 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000217844 "BcDNA:LD32788, CG17273, PURA_DROME, AdSS" "IPR001114:Adenylosuccinate synthetase, IPR018220:Adenylosuccinate synthase, GTP-binding site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033128:Adenylosuccinate synthase, active site" CG17273 11-Aug-17 DroID_v2017_08 "Drer\adssl, Drer\adssl1, Drer\adss" Scer\ADE12 Cele\adss-1 "Xtro\adssl1, Xtro\adss" "Mmus\Adssl1, Mmus\Adss" "Hsap\ADSS, Hsap\ADSSL1" "lethal - all die during larval stage,recessive,long lived,lethal,neuroanatomy defective,viable" ganglion mother cell DRSC14162 K -1.165420469 0.037736422 -0.57451367 0.156889503 2.061754958 0.047266587 FBgn0067406 Pcp-1 Pcp-1 cuticular protein http://flybase.org/reports/FBgn0067406 gene - - - Pcp-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026334 Svop SVtwo-related protein http://flybase.org/reports/FBgn0026334 - gene - - - "SVOP, Svop" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083033 snoRNA:Psi18S-525f snoRNA:Psi18S-525f http://flybase.org/reports/FBgn0083033 snoRNA_gene - - - "snoRNA:Psi18S-525f, psi18S-525f, CR34579" - CR34579 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261000 AGAR-52 Autosomal general anesthetic resistant 52 http://flybase.org/reports/FBgn0261000 gene - - - AGAR-52 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0023116 anon-10Ar anon-10Ar http://flybase.org/reports/FBgn0023116 - gene - - - "11, anon-10Ar" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037707 RnpS1 RNA-binding protein S1 http://flybase.org/reports/FBgn0037707 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "RNA splicing ; GO:0008380 | inferred from mutant phenotype negative regulation of transposition, DNA-mediated ; GO:0000335 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from direct assay "DEK, CG16788, cg16788, RnpS1, rnps1, RNPS1, Rnps1" "IPR000504:RNA recognition motif domain, IPR034201:RNPS1, RNA recognition motif" CG16788 11-Aug-17 DroID_v2017_08 "Drer\pabpn1l, Drer\LOC103909923, Drer\rnps1, Drer\srsf2b, Drer\srsf2a, Drer\pabpn1" Scer\SGN1 "Cele\rnp-5, Cele\rsp-4" "Xtro\pabpn1l, Xtro\pabpn1, Xtro\rnps1, Xtro\srsf2" "Mmus\Rnps1, Mmus\Srsf2, Mmus\Pabpn1l, Mmus\Bcl2l2, Mmus\Pabpn1" "Hsap\PABPN1, Hsap\RNPS1, Hsap\SRSF2, Hsap\BCL2L2-PABPN1, Hsap\BCL2L2, Hsap\PABPN1L"

"neuroanatomy defective,female semi-sterile,female sterile" "intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" DRSC15154 E 1.227943017 1.301145037 1.50919055 0.868104742 -0.394009413 0.135163129 FBgn0262794 CG43175 - http://flybase.org/reports/FBgn0262794 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43175 - CG43175 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022337 da::Drer\E12 E12 http://flybase.org/reports/FBgn0022337 - engineered_fusion_gene - - - "da::Brer\E12, da::Drer\E12" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028738 ETH Ecdysis triggering hormone http://flybase.org/reports/FBgn0028738 protein_coding_gene ecdysis-triggering hormone activity ; GO:0008255 | non-traceable author statement neuropeptide hormone activity ; GO:0005184 | traceable author statement ecdysis-triggering hormone activity ; GO:0008255 | inferred from direct assay G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with ETHR receptor binding ; GO:0005102 | inferred from sequence or structural similarity "ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | traceable author statement neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern ecdysis, chitin-based cuticle ; GO:0018990 | inferred from direct assay" extracellular space ; GO:0005615 | inferred by curator from GO:0008255 extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "eth, Drm-ETH-1, Drm-ETH-2, ETH-1, ETH2, ETH1, CG18105, DmETH, ETH, ETH-2, Eth" - CG18105 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,behavior defective,lethal - all die before end of larval stage,some die during larval stage,recessive,viable" "tracheal system,trachea,embryonic/larval cuticle" FBgn0010187 tu(3)pb tu(3)pb http://flybase.org/reports/FBgn0010187 - gene - - - "tu-pb, Tu-pb, tu(3)pb" - - 11-Aug-17 DroID_v2017_08 - - - - - - melanotic mass phenotype proboscis FBgn0034935 Orcokinin Orcokinin http://flybase.org/reports/FBgn0034935 protein_coding_gene - - - "BcDNA:RH09340, CG13565, Orcokinin, CG1565, orcokinin, Orco" - CG13565 11-Aug-17 DroID_v2017_08 - - "Cele\F46C5.1, Cele\F46C5.10" - - - viable FBgn0000294 Cg63-64 Collagen-like 63-64 http://flybase.net/reports/FBgn0000294.html gene "DCg8, Cg8" 11-Aug-17 DroID_v2017_08 FBgn0035551 CG7465 - http://flybase.org/reports/FBgn0035551 protein_coding_gene - - - CG7465 "IPR004011:GYR motif, IPR004019:YLP motif" CG7465 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,supernumerary,mesothoracic tergum" FBgn0037498 CG10029 - http://flybase.org/reports/FBgn0037498 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 protein disulfide isomerase activity ; GO:0003756 | inferred from sequence or structural similarity with SGD:S000002926 peptide disulfide oxidoreductase activity ; GO:0015037 | inferred from sequence or structural similarity with SGD:S000002926 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 protein folding ; GO:0006457 | inferred from sequence or structural similarity with SGD:S000002926 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000002926 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 CG10029 "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain" CG10029 11-Aug-17 DroID_v2017_08 Drer\erp44 "Scer\PDI1, Scer\MPD1, Scer\EUG1" "Cele\F42G8.7, Cele\C06A6.5, Cele\C30H7.2" Xtro\erp44 Mmus\Erp44 Hsap\ERP44 viable FBgn0031240 CG3345 - http://flybase.org/reports/FBgn0031240 protein_coding_gene - - mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001858153 "anon-WO0140519.207, CG3345" - CG3345 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Gm595, Mmus\Fsip2" Hsap\FSIP2 viable FBgn0011065 l(1)Q18 lethal (1) Q18 http://flybase.org/reports/FBgn0011065 FBgn0010210 gene - - - l(1)Q18 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031148 Cbs Cystathionine beta-synthase http://flybase.org/reports/FBgn0031148 protein_coding_gene cystathionine beta-synthase activity ; GO:0004122 | inferred from electronic annotation with InterPro:IPR005857 pyridoxal phosphate binding ; GO:0030170 | inferred from biological aspect of ancestor with PANTHER:PTN000034104 cysteine biosynthetic process via cystathionine ; GO:0019343 | inferred from electronic annotation with InterPro:IPR005857 cysteine biosynthetic process from serine ; GO:0006535 | inferred from electronic annotation with InterPro:IPR001216 response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000034104 "CG1753, Cbs, dCBS, CBS, DmCBS" "IPR000644:CBS domain, IPR001216:Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site, IPR001926:Tryptophan synthase beta subunit-like PLP-dependent enzyme, IPR005857:Cystathionine beta-synthase" CG1753 11-Aug-17 DroID_v2017_08 "Drer\cbsa, Drer\cbsb" Scer\CYS4 "Cele\cysl-4, Cele\cbs-2, Cele\cysl-2, Cele\cysl-3, Cele\cysl-1, Cele\T25D3.3, Cele\cbs-1, Cele\F01D4.8, Cele\F13B12.4" Xtro\cbs Mmus\Cbs "Hsap\CBS, Hsap\CBSL" "short lived,long lived,RU486 conditional,viable,fertile" FBgn0262967 CR43278 - http://flybase.org/reports/FBgn0262967 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available - "CG43278, CR43278, mdcds_60948" - CR43278 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046644 anon-38D.22 anon-38D.22 http://flybase.org/reports/FBgn0046644 gene - - - "38D.22, anon-38D.22" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033483 egr eiger http://flybase.org/reports/FBgn0033483 protein_coding_gene tumor necrosis factor receptor binding ; GO:0005164 | inferred from electronic annotation with InterPro:IPR006052 tumor necrosis factor receptor superfamily binding ; GO:0032813 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with wgn tumor necrosis factor receptor binding ; GO:0005164 | non-traceable author statement tumor necrosis factor receptor binding ; GO:0005164 | traceable author statement receptor binding ; GO:0005102 | inferred from direct assay tumor necrosis factor receptor superfamily binding ; GO:0032813 | inferred from sequence or structural similarity with HGNC:11892 JNK cascade ; GO:0007254 | inferred from mutant phenotype inferred from genetic interaction with bsk inferred from genetic interaction with hep inferred from genetic interaction with msn inferred from genetic interaction with Tak1 apoptotic process ; GO:0006915 | inferred from mutant phenotype melanization defense response ; GO:0035006 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with Ank2 extrinsic apoptotic signaling pathway ; GO:0097191 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | inferred from mutant phenotype apical protein localization ; GO:0045176 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from genetic interaction with Ank2 innate immune response ; GO:0045087 | inferred from mutant phenotype glial cell proliferation ; GO:0014009 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype engulfment of apoptotic cell ; GO:0043652 | inferred from mutant phenotype apoptotic process ; GO:0006915 | non-traceable author statement apoptotic process ; GO:0006915 | inferred from direct assay immune response ; GO:0006955 | inferred from mutant phenotype positive regulation of sensory perception of pain ; GO:1904058 | inferred from mutant phenotype spanning component of plasma membrane ; GO:0044214 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG12919, Ect1, regg1, darth, dt1, BcDNA:RH51659, egr, Egr, TNF-alpha, Regg1, TNF, eiger, TNFalpha, Eiger" "IPR006052:Tumour necrosis factor domain, IPR008983:Tumour necrosis factor-like domain, IPR021184:Tumour necrosis factor, conserved site" CG12919 11-Aug-17 DroID_v2017_08 "Drer\tnfsf12, Drer\eda, Drer\tnfsf13b, Drer\tnfsf13" - Cele\col-165 - "Mmus\Tnfsf13, Mmus\Eda, Mmus\Tnfsf13b, Mmus\Tnfsf11, Mmus\Tnfsf12, Mmus\Tnfsfm13" "Hsap\TNFSF13, Hsap\TNFSF12, Hsap\TNFSF12-TNFSF13, Hsap\TNFSF13B, Hsap\EDA" embryonic stage | cellular blastoderm dorsal ectoderm anlage

"immune response defective,viable,fertile,visible,size defective,increased cell death,cell death defective,nutrition conditional,feeding behavior defective,somatic clone,partially lethal - majority die,heat sensitive,partially lethal - majority live,temperature conditional,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage" "eye,plasmatocyte,wing disc | third instar larval stage,wing,macrochaeta & scutellum-537.4,macrochaeta & mesothoracic tergum-537.4,adult abdomen,embryonic/larval hemolymph,egg chamber,nutrition conditional,follicle cell,somatic clone,eye photoreceptor cell | third instar larval stage,embryonic/larval optic stalk,embryonic/larval hemolymph | third instar larval stage,eye-antennal disc,scutellum,wing margin,wing disc,ventral furrow" FBgn0021810 l(2)k16529 lethal (2) k16529 http://flybase.org/reports/FBgn0021810 - gene - - - l(2)k16529 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027117 mei-P15 mei-P15 http://flybase.org/reports/FBgn0027117 - gene - - - mei-P15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0013515 l(1)14Ad lethal (1) 14Ad http://flybase.org/reports/FBgn0013515 - gene - - - "XIV, l(1)XIV, l(1)13Fg, l(1)14Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040817 CG14132 - http://flybase.org/reports/FBgn0040817 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from biological aspect of ancestor with PANTHER:PTN002219240 extracellular space ; GO:0005615 | inferred from sequence model "CG14132, DIGF-7" IPR029277:Single domain Von Willebrand factor type C domain CG14132 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032715 CG17597 - http://flybase.org/reports/FBgn0032715 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002155, InterPro:IPR020613, InterPro:IPR020615, InterPro:IPR020616, InterPro:IPR020617" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002155, InterPro:IPR016039, InterPro:IPR020613, InterPro:IPR020615, InterPro:IPR020616, InterPro:IPR020617" peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:10606 inferred from sequence model CG17597 "IPR002155:Thiolase, IPR016039:Thiolase-like, IPR020613:Thiolase, conserved site, IPR020615:Thiolase, acyl-enzyme intermediate active site, IPR020617:Thiolase, C-terminal, IPR020616:Thiolase, N-terminal" CG17597 11-Aug-17 DroID_v2017_08 "Drer\LOC100330644, Drer\scp2b, Drer\scp2a" Scer\FOX2 Cele\daf-22 "Xtro\rsbn1, Xtro\scp2, Xtro\rsbn1l" "Mmus\Rsbn1, Mmus\Scp2d1, Mmus\Rsbn1l, Mmus\Scp2" "Hsap\SCP2, Hsap\CTDSP2, Hsap\SCP2D1, Hsap\RSBN1L" viable FBgn0013627 l(3)neo23 lethal (3) neo23 http://flybase.org/reports/FBgn0013627 - gene - - - l(3)neo23 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085228 CG34199 - http://flybase.org/reports/FBgn0085228 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34199 IPR032011:Domain of unknown function DUF4794 CG34199 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011589 Elk Eag-like K[+] channel http://flybase.org/reports/FBgn0011589 - protein_coding_gene phosphorelay sensor kinase activity ; GO:0000155 | inferred from electronic annotation with InterPro:IPR000700 voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 voltage-gated cation channel activity ; GO:0022843 | inferred from sequence or structural similarity with eag voltage-gated potassium channel activity ; GO:0005249 | non-traceable author statement transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 phosphorelay signal transduction system ; GO:0000160 | inferred from electronic annotation with InterPro:IPR000700 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 potassium ion transport ; GO:0006813 | non-traceable author statement potassium ion transport ; GO:0006813 | inferred from sequence or structural similarity with eag regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 voltage-gated potassium channel complex ; GO:0008076 | non-traceable author statement voltage-gated potassium channel complex ; GO:0008076 | inferred from sequence or structural similarity with eag "CG5076, dmELK, Elk, elk" "IPR018490:Cyclic nucleotide-binding-like, IPR000014:PAS domain, IPR000595:Cyclic nucleotide-binding domain, IPR000700:PAS-associated, C-terminal, IPR001610:PAC motif, IPR003938:Potassium channel, voltage-dependent, EAG/ELK/ERG, IPR003950:Potassium channel, voltage-dependent, ELK, IPR005821:Ion transport domain, IPR014710:RmlC-like jelly roll fold" CG5076 11-Aug-17 DroID_v2017_08 "Drer\hcn4l, Drer\hcn4, Drer\kcnh7, Drer\kcnh2a, Drer\hcn3, Drer\kcnh5a, Drer\kcnh1a, Drer\kcnh4b, Drer\kcnh5b, Drer\hcn2b, Drer\kcnh4a, Drer\kcnh8, Drer\kcnh6b, Drer\kcnh6a, Drer\LOC101883600, Drer\kcnh3, Drer\si:rp71-68n21.12, Drer\kcnh1b, Drer\LOC100334297" - Cele\cng-3 "Xtro\kcnh1, Xtro\kcnh6, Xtro\kcnh8, Xtro\hcn4, Xtro\hcn1, Xtro\kcnh7" "Mmus\Kcnh2, Mmus\Hcn3, Mmus\Kcnh8, Mmus\Hcn4, Mmus\Kcnh6, Mmus\Kcnh5, Mmus\Kcnh7, Mmus\Hcn1, Mmus\Kcnh1, Mmus\Hcn2, Mmus\Kcnh4, Mmus\Kcnh3" "Hsap\KCNH7, Hsap\HCN2, Hsap\HCN4, Hsap\KCNH8, Hsap\KCNH1, Hsap\KCNH5, Hsap\KCNH6, Hsap\KCNH4, Hsap\KCNH3, Hsap\HCN1, Hsap\HCN3, Hsap\KCNH2" "partially lethal - majority die,some die during pupal stage,viable" FBgn0028023 l(3)S103710 lethal (3) S103710 http://flybase.org/reports/FBgn0028023 gene - - - "1037/10, l(3)S103710" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051542 CG31542 - http://flybase.org/reports/FBgn0051542 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs29h01, NEST:bs08f12, NEST:bs01d10, BcDNA:AT15479, CG31542" - CG31542 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC21544 E -1.496970381 -1.136386051 -1.161421121 -2.274157499 0.336180417 0.607748264 FBgn0025739 pon partner of numb http://flybase.org/reports/FBgn0025739 - protein_coding_gene - embryonic heart tube development ; GO:0035050 | inferred from genetic interaction with jumu inferred from genetic interaction with CHES-1-like asymmetric neuroblast division ; GO:0055059 | traceable author statement asymmetric protein localization ; GO:0008105 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay basal part of cell ; GO:0045178 | traceable author statement cell cortex ; GO:0005938 | inferred from direct assay basal cortex ; GO:0045180 | non-traceable author statement "Pon, PON, CG3346, pon" IPR015943:WD40/YVTN repeat-like-containing domain CG3346 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage " neuroblast

, myoblast

, sensory mother cell

" " prepupal stage , embryonic stage , embryonic stage | stage 13-14 , embryonic stage | stage 10-11 " " external sensory organ precursor cell && imaginal disc

, neuroblast

, sensory mother cell

, myoblast

" "viable,fertile,hyperplasia,somatic clone,neuroanatomy defective" "neuroblast,somatic clone,embryonic/larval pericardial cell,abdominal 2 lateral transverse muscle 3,abdominal 3 lateral transverse muscle 3,abdominal 4 lateral transverse muscle 3,abdominal 5 lateral transverse muscle 3,abdominal 6 lateral transverse muscle 3,abdominal 7 lateral transverse muscle 3,embryonic/larval somatic muscle" FBgn0037483 CG14609 - http://flybase.org/reports/FBgn0037483 protein_coding_gene - - - CG14609 - CG14609 11-Aug-17 DroID_v2017_08 Drer\ccdc151 - - - - Hsap\UACA FBgn0016712 Reg-17 Rhythmically expressed gene 17 http://flybase.org/reports/FBgn0016712 - gene - - - "Dreg-17, Reg-17" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , embryonic stage | late " adult head

FBgn0265606 Prosalpha4T1 "Proteasome alpha4 subunit, Testis-specific 1" http://flybase.org/reports/FBgn0265606 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 molecular_function ; GO:0003674 | no biological data available" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000005398 "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from sequence or structural similarity with SGD:S000005398" "Pros28.1A, CG17268, alpha4T1, Prosalpha4T1, alpha4t1, a4-t1, dalpha7, alpha4t1_dm, pros28.1A, Pros28.2" "IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR023332:Proteasome alpha-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG17268 11-Aug-17 DroID_v2017_08 "Drer\psma2, Drer\psma8" Scer\PRE6 Cele\pas-4 "Xtro\psma7, Xtro\psma2, Xtro\psma5" "Mmus\Psma8, Mmus\Psma5, Mmus\Psma7, Mmus\Psma2" "Hsap\PSMA5, Hsap\PSMA7, Hsap\PSMA2, Hsap\PSMA8" DRSC28895 K -0.105060456 -0.465304183 -0.295765505 0.516458549 2.62304026 1.352178717 FBgn0005516 l(1)DC1112 lethal (1) DC1112 http://flybase.org/reports/FBgn0005516 - gene - - - l(1)DC1112 - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,recessive,lethal" FBgn0021841 l(2)k14902 lethal (2) k14902 http://flybase.org/reports/FBgn0021841 - gene - - - l(2)k14902 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032080 CG9525 - http://flybase.org/reports/FBgn0032080 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017850 molecular_function ; GO:0003674 | no biological data available metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017850 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG9525, gi7297470" "IPR017850:Alkaline-phosphatase-like, core domain, IPR004245:Protein of unknown function DUF229, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG9525 11-Aug-17 DroID_v2017_08 - - "Cele\F10C2.3, Cele\Y41E3.1, Cele\F15H10.7, Cele\R03G8.3, Cele\F32G8.2, Cele\F07C3.3, Cele\Y73F8A.35, Cele\F32D8.2, Cele\Y38A10A.2, Cele\T07G12.3, Cele\K03A11.4, Cele\T23E1.1, Cele\R03G8.1, Cele\M03F8.5" - - - DRSC03249 I 2.085457933 0.516635877 1.249179374 0.904306587 -1.178757528 -0.044796488 FBgn0023427 olfactory-defective-A olfactory defective A http://flybase.org/reports/FBgn0023427 - gene - - - "odA, olfactory-defective-A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,recessive" FBgn0066361 john john http://flybase.org/reports/FBgn0066361 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available john - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,memory defective,chemical sensitive" FBgn0261992 CG42810 - http://flybase.org/reports/FBgn0261992 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42810, CG16849" - CG42810 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0061143 l(3)S000616b lethal (3) S000616b http://flybase.org/reports/FBgn0061143 gene - - - "0006/16, l(3)S000616b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015288 RpL22 Ribosomal protein L22 http://flybase.org/reports/FBgn0015288 FBgn0025289 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002671 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG7434, rpL22, EG:BACR19J1.4, rpl22, Rpl22, PBP-12, RL22, L22, anon-EST:Posey53, RpL22, RPL22, Rp L22, RL22_DROME" IPR002671:Ribosomal protein L22e CG7434 11-Aug-17 DroID_v2017_08 "Drer\rpl22l1, Drer\rpl22" "Scer\RPL22B, Scer\RPL22A" Cele\rpl-22 "Xtro\rpl22l1, Xtro\rpl22" "Mmus\Rpl22l1, Mmus\Rpl22" "Hsap\RPL22, Hsap\RPL22L1" "lethal,recessive" DRSC22819 IEK -1.501733944 0.101010891 5.430292018 -3.853988658 0.132640886 3.696400528 FBgn0014897 anon-10Ad anon-10Ad http://flybase.org/reports/FBgn0014897 - gene - - - anon-10Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035104 CG13875 - http://flybase.org/reports/FBgn0035104 protein_coding_gene - - - "CG13875, RE30146P" "IPR029071:Ubiquitin-related domain, IPR033593:N-terminal RASSF family" CG13875 11-Aug-17 DroID_v2017_08 "Drer\rassf8b, Drer\rassf7a, Drer\rassf10a, Drer\rassf9, Drer\rassf7b, Drer\LOC100003291" - - "Xtro\rassf10, Xtro\rassf9, Xtro\rassf8, Xtro\rassf7" "Mmus\Rassf10, Mmus\Rassf9, Mmus\Rassf7, Mmus\Rassf8" "Hsap\RASSF10, Hsap\RASSF8, Hsap\RASSF9, Hsap\RASSF7" "viable,fertile" FBgn0041757 eth-as313 eth-as313 http://flybase.org/reports/FBgn0041757 gene - - - "eth[as]313, eth-as313" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0040575 CG15922 - http://flybase.org/reports/FBgn0040575 protein_coding_gene - - - "BcDNA:RH34302, CG15922" - CG15922 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041137 l(2)44Ea lethal (2) 44Ea http://flybase.org/reports/FBgn0041137 gene - - - l(2)44Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0033688 Prp8 pre-mRNA processing factor 8 http://flybase.org/reports/FBgn0033688 protein_coding_gene U6 snRNA binding ; GO:0017070 | inferred from electronic annotation with InterPro:IPR019580 U5 snRNA binding ; GO:0030623 | inferred from electronic annotation with InterPro:IPR019581 snRNA binding ; GO:0017069 | inferred from sequence or structural similarity with SGD:S000001208 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000001208 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 ventral cord development ; GO:0007419 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from physical interaction with CG12320 inferred from physical interaction with CG4849 inferred from physical interaction with l(3)72Ab inferred from physical interaction with l(3)72Ab cytoplasm ; GO:0005737 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity with SGD:S000001208 "prp8, CG8877, E-2e, Prp8, A1Z8U0" "IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR012591:PRO8NT domain, IPR012592:PROCN domain, IPR012984:PROCT domain, IPR012337:Ribonuclease H-like domain, IPR019580:Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding, IPR019581:Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding, IPR019582:RNA recognition motif, spliceosomal PrP8, IPR027652:Pre-mRNA-processing-splicing factor 8, IPR021983:PRP8 domain IV core" CG8877 11-Aug-17 DroID_v2017_08 Drer\prpf8 Scer\PRP8 Cele\prp-8 Xtro\prpf8 Mmus\Prpf8 Hsap\PRPF8 "increased cell death,small body,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,partially lethal - majority die,visible,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,wing disc,anterior crossvein,1st posterior cell,prothoracic gland | larval stage,scutellar bristle,wing" DRSC07293 I -0.734796401 2.267346494 -0.281473739 -1.026809643 -1.188915651 -0.818240457 FBgn0053386 5SrRNA:CR33386 5SrRNA:CR33386 http://flybase.org/reports/FBgn0053386 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33386, 5SrRNA:CR33386" - CR33386 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060731 l(3)S067304 lethal (3) S067304 http://flybase.org/reports/FBgn0060731 gene - - - "0673/04, l(3)S067304" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0264879 CR44070 - http://flybase.org/reports/FBgn0264879 non_protein_coding_gene - - - CR44070 - CR44070 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032923 CG9248 - http://flybase.org/reports/FBgn0032923 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001736 - - CG9248 "IPR001736:Phospholipase D/Transphosphatidylase, IPR032803:PLD-like domain" CG9248 11-Aug-17 DroID_v2017_08 "Drer\pld3, Drer\si:ch211-194e18.2, Drer\si:dkeyp-110e4.6, Drer\LOC101885593" - "Cele\Y51A2D.13, Cele\T05C3.6, Cele\E04F6.4, Cele\F09G2.8" Xtro\pld3 "Mmus\Pld3, Mmus\Pld5, Mmus\Pld4" "Hsap\PLD5, Hsap\PLD4, Hsap\PLD3" viable FBgn0003395 shm short macros http://flybase.org/reports/FBgn0003395 - gene - - - shm - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,visible,viable,male,reduced" macrochaeta FBgn0033886 Rpn13 Regulatory particle non-ATPase 13 http://flybase.org/reports/FBgn0033886 protein_coding_gene proteasome binding ; GO:0070628 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000004413 endopeptidase activator activity ; GO:0061133 | inferred from sequence or structural similarity with UniProtKB:Q16186 endopeptidase activator activity ; GO:0061133 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 proteasome assembly ; GO:0043248 | inferred from sequence or structural similarity with UniProtKB:Q16186 lateral inhibition ; GO:0046331 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity with SGD:S000004413 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 "cytoplasm ; GO:0005737 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000004413 proteasome complex ; GO:0000502 | inferred from sequence or structural similarity with UniProtKB:Q16186 proteasome regulatory particle ; GO:0005838 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000259827" "GC13349, p42E, CG13349, Rpn13" "IPR006773:26S proteasome complex ubiquitin receptor, subunit Rpn13, IPR032368:UCH-binding domain" CG13349 11-Aug-17 DroID_v2017_08 Drer\adrm1 Scer\RPN13 Cele\rpn-13 Xtro\adrm1 Mmus\Adrm1 Hsap\ADRM1 "viable,visible,neuroanatomy defective" "chaeta,supernumerary,intersegmental nerve,anterior fascicle & synapse" FBgn0265537 CR44387 - http://flybase.org/reports/FBgn0265537 non_protein_coding_gene - - - "CR44387, lincRNA.332" - CR44387 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262228 mir-975 mir-975 stem loop http://flybase.org/reports/FBgn0262228 miRNA_gene - - - "mir-975, CR42935, miR-975" - CR42935 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016055 pir pirouette http://flybase.org/reports/FBgn0016055 - gene - - - pir - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced,auditory perception defective,behavior defective" "optic lobe,photoreceptor cell,axon,ommatidium" FBgn0069081 sna::wor sna::wor http://flybase.org/reports/FBgn0069081 engineered_fusion_gene - - - sna::wor - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032335 CG14915 - http://flybase.org/reports/FBgn0032335 protein_coding_gene - - - CG14915 - CG14915 11-Aug-17 DroID_v2017_08 - - - - - - "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0261997 CG42815 - http://flybase.org/reports/FBgn0261997 protein_coding_gene - - - "CG42815, CG32186, CG5587, CG5944" - CG42815 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0002219 l(3)67BDq lethal (3) 67BDq http://flybase.org/reports/FBgn0002219 - gene - - - l(3)67BDq - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0045861 cact::Hsap\NFKBIA NFKBIA http://flybase.org/reports/FBgn0045861 engineered_fusion_gene - - - cact::Hsap\NFKBIA - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0065715 l(2)SH0579 lethal (2) SH0579 http://flybase.org/reports/FBgn0065715 gene - - - "l(2)SH0579, l(2)SH2 0579" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263219 Dscam4 Down syndrome cell adhesion molecule 4 http://flybase.org/reports/FBgn0263219 protein_coding_gene identical protein binding ; GO:0042802 | inferred from sequence or structural similarity with Dscam2 cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with Dscam2 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG33274, Dscam4, CG42330, CG13672, CG7060, CG18630, CT21829" "IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013098:Immunoglobulin I-set" CG42330 11-Aug-17 DroID_v2017_08 "Drer\nfasca, Drer\mylk3, Drer\nrcama, Drer\mylk4a, Drer\mylk4b, Drer\dscamb, Drer\chl1b, Drer\dscama, Drer\spegb, Drer\mylkb, Drer\si:dkey-250k15.7, Drer\nadl1.1, Drer\mylka, Drer\dscaml1" - "Cele\unc-89, Cele\him-4, Cele\egl-15, Cele\ZC373.4, Cele\ver-3" "Xtro\mylk3, Xtro\dscam, Xtro\mylk4, Xtro\mylk, Xtro\dscaml1" "Mmus\Mylk4, Mmus\L1cam, Mmus\Mylk3, Mmus\Dscam, Mmus\Mylk2, Mmus\Nrcam, Mmus\Mylk, Mmus\Nfasc, Mmus\Dscaml1, Mmus\Speg" "Hsap\NRCAM, Hsap\MYLK4, Hsap\SPEG, Hsap\NFASC, Hsap\DSCAML1, Hsap\HSPG2, Hsap\MYLK2, Hsap\DSCAM, Hsap\VSIG10L, Hsap\L1CAM, Hsap\MYLK3, Hsap\MYLK" FBgn0267586 CR45924 - http://flybase.org/reports/FBgn0267586 non_protein_coding_gene - - - CR45924 - CR45924 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085321 CG34292 - http://flybase.org/reports/FBgn0085321 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34292 - CG34292 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002827 ms(2)E6 male sterile (2) E6 http://flybase.org/reports/FBgn0002827 - gene - - - "ms2.6, ms(2)2.6, ms(2)E6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0260858 Ykt6 YKT6 v-SNARE http://flybase.org/reports/FBgn0260858 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with HGNC:16959 SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with HGNC:16959 SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 "ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with HGNC:16959 exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with HGNC:16959 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001388 integral component of membrane ; GO:0016021 | NOT traceable author statement SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with HGNC:16959 transport vesicle ; GO:0030133 | inferred from sequence or structural similarity endosome ; GO:0005768 | inferred from sequence or structural similarity with HGNC:16959 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:16959 SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 "CG1515, YKT6, Ykt6p, Ykt6, l(1)G0155, cg1515" "IPR001388:Synaptobrevin, IPR010908:Longin domain, IPR011012:Longin-like domain" CG1515 11-Aug-17 DroID_v2017_08 "Drer\sybl1, Drer\ykt6, Drer\sec22bb, Drer\sec22a, Drer\vamp8, Drer\vamp1, Drer\sec22c, Drer\sec22ba, Drer\vamp2, Drer\zgc:92912" Scer\YKT6 "Cele\vamp-8, Cele\ykt-6, Cele\snb-1, Cele\vamp-7, Cele\sec-22" "Xtro\vamp1, Xtro\ykt6, Xtro\vamp2, Xtro\vamp7, Xtro\sec22c, Xtro\sec22a, Xtro\vamp3, Xtro\sec22b, Xtro\vamp4" "Mmus\Vamp4, Mmus\Ykt6, Mmus\Vamp2, Mmus\Vamp1, Mmus\Sec22a, Mmus\Vamp8, Mmus\Sec22c, Mmus\Vamp7, Mmus\Vamp3, Mmus\Sec22b" "Hsap\SEC22B, Hsap\VAMP3, Hsap\VAMP4, Hsap\YKT6, Hsap\VAMP1, Hsap\VAMP8, Hsap\SEC22C, Hsap\VAMP2, Hsap\VAMP7" FBgn0026166 su(rdgB)82 su(rdgB)82 http://flybase.org/reports/FBgn0026166 - gene - - - su(rdgB)82 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033344 CG8252 - http://flybase.org/reports/FBgn0033344 protein_coding_gene - - - CG8252 IPR025663:A-kinase anchor protein 28kDa CG8252 11-Aug-17 DroID_v2017_08 - - - - Mmus\Akap14 Hsap\AKAP14 FBgn0002318 l(3)85Eb lethal (3) 85Eb http://flybase.org/reports/FBgn0002318 - gene - - - "l(3)SG35, l(3)J5, l(3)85Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" FBgn0002263 l(3)69Ab lethal (3) 69Ab http://flybase.org/reports/FBgn0002263 - gene - - - "rsg25, l(3)rsg25, l(3)69Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259343 C7 - http://flybase.org/reports/FBgn0259343 gene - - - C7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing vein,wing hair" FBgn0014876 Pt9 Protein 9 http://flybase.org/reports/FBgn0014876 - gene - - - Pt9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004183 snRNA:U1:82Eb small nuclear RNA U1 at 82Eb http://flybase.org/reports/FBgn0004183 "FBgn0003915, FBgn0003917" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity chromatin organization ; GO:0006325 | inferred from mutant phenotype" U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity "U1, U1 snRNA, U1a-82Eb, U1-82.3, U1snRNA, K5, snRNA-U1-82.3, U1snRNA82Eb, CR32862, snRNA:U1, snRNA:U1:82Eb, U1:82Eb, U1-82Eb, chr3R:773643..773870, snRNA:U1:82 Eb" - CR32862 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266146 CR44852 - http://flybase.org/reports/FBgn0266146 non_protein_coding_gene - - - CR44852 - CR44852 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035204 CG2277 - http://flybase.org/reports/FBgn0035204 protein_coding_gene 5'-nucleotidase activity ; GO:0008253 | inferred from biological aspect of ancestor with PANTHER:PTN000250728 - - "CG2277, 28575006" "IPR008380:HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase, IPR023214:HAD-like domain" CG2277 11-Aug-17 DroID_v2017_08 "Drer\nt5dc1, Drer\nt5c2l1" - - "Xtro\nt5dc4, Xtro\nt5c2, Xtro\abhd10" "Mmus\Nt5dc1, Mmus\Nt5c2" "Hsap\NT5C2, Hsap\NT5DC4, Hsap\NT5DC1" viable FBgn0042186 CG17239 - http://flybase.org/reports/FBgn0042186 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP138, CG17239" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG17239 11-Aug-17 DroID_v2017_08 "Drer\gzmk, Drer\si:ch211-165b19.8" - "Cele\svh-1, Cele\try-1" "Xtro\gzmak, Xtro\gzmh" "Mmus\Prss53, Mmus\Mcpt4, Mmus\Cma2, Mmus\Prtn3, Mmus\Prss55, Mmus\Klk9, Mmus\Klk14, Mmus\Prss36" "Hsap\CMA1, Hsap\PRSS53, Hsap\AZU1, Hsap\KLK14, Hsap\GZMA, Hsap\PRSS36, Hsap\KLK11" FBgn0034195 Spn53F Serpin 53F http://flybase.org/reports/FBgn0034195 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG10956, Spn53F" "IPR000215:Serpin family, IPR023796:Serpin domain" CG10956 11-Aug-17 DroID_v2017_08 "Drer\serping1, Drer\agt, Drer\serpinf2a, Drer\serpini1, Drer\serpind1, Drer\zgc:174260, Drer\serpine2, Drer\serpinf1, Drer\serpina7, Drer\serpinf2b" - "Cele\C28G1.2, Cele\srp-6, Cele\srp-3, Cele\srp-1, Cele\srp-7, Cele\srp-2, Cele\srp-8" "Xtro\serpine2, Xtro\serpini1" "Mmus\Serpinb2, Mmus\Serpinf1, Mmus\Serpinf2, Mmus\Serpine1, Mmus\Serpind1, Mmus\Agt, Mmus\Serpini2, Mmus\Serpine2, Mmus\Serpini1, Mmus\Serpinb7" "Hsap\SERPINI2, Hsap\SERPINB2, Hsap\SERPINF2, Hsap\SERPIND1, Hsap\AGT, Hsap\SERPINE1, Hsap\SERPINI1, Hsap\SERPINF1, Hsap\SERPINE2, Hsap\SERPINB7, Hsap\SERPINA7" viable FBgn0069103 mus321 mutagen-sensitive 321 http://flybase.org/reports/FBgn0069103 gene - - - mus321 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0265913 CR44702 - http://flybase.org/reports/FBgn0265913 non_protein_coding_gene - - - "lincRNA.554, CR44702, R5_3L:14878427..14879399" - CR44702 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000203 bod bowed http://flybase.org/reports/FBgn0000203 - gene - - - bod - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "wing,eye" FBgn0261879 Z2-3941 - http://flybase.org/reports/FBgn0261879 gene - sleep ; GO:0030431 | inferred from mutant phenotype - Z2-3941 - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective FBgn0065076 snoRNA:185 snoRNA:185 http://flybase.org/reports/FBgn0065076 snoRNA_gene - - - "snoRNA:185, Dm-185, snoR185, CR33930, DmOr_cd5(SnoR185)" - CR33930 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013509 l(1)Uc-1 lethal (1) Uc-1 http://flybase.org/reports/FBgn0013509 - gene - - - l(1)Uc-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002484 l(3)SG43 lethal (3) SG43 http://flybase.org/reports/FBgn0002484 FBgn0005204 gene - - - "l(3)dsl-10, l(3)dsl10, l(3)A10, 7m63, l(3)SG43" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0023070 l(1)20Ag lethal (1) 20Ag http://flybase.org/reports/FBgn0023070 - gene - - - "B2/45.8, l(1)20Ag" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002289 l(3)73Cd lethal (3) 73Cd http://flybase.org/reports/FBgn0002289 - gene - - - "l(3)73CD, l(3)73Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal tergite FBgn0038928 Fadd Fas-associated death domain http://flybase.org/reports/FBgn0038928 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8IRY7 CARD domain binding ; GO:0050700 | inferred from physical interaction with Dredd protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NHG0 protein binding ; GO:0005515 | inferred from physical interaction with Myd88 defense response to Gram-negative bacterium ; GO:0050829 | inferred from genetic interaction with PGRP-LE apoptotic process ; GO:0006915 | non-traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement immune response ; GO:0006955 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from direct assay positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | traceable author statement peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from genetic interaction with imd positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "dFADD, FADD, Fadd, dFadd, CG12297, dfadd, fadd, BG4, BG4_DROME" "IPR000488:Death domain, IPR011029:Death-like domain" CG12297 11-Aug-17 DroID_v2017_08 "Drer\zgc:174906, Drer\fadd" - - - "Mmus\Fadd, Mmus\Pidd1" "Hsap\FADD, Hsap\PIDD1" "viable,fertile,immune response defective,recessive,wild-type" spermatid FBgn0263249 CG43392 - http://flybase.org/reports/FBgn0263249 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43392 - CG43392 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034599 hng1 hinge1 http://flybase.org/reports/FBgn0034599 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - - "CG9437, hng1" "IPR004210:BESS motif, IPR006578:MADF domain" CG9437 11-Aug-17 DroID_v2017_08 "Drer\LOC100330838, Drer\si:ch211-207i20.3, Drer\zgc:152938, Drer\si:ch73-59f11.3" - "Cele\madf-3, Cele\madf-5, Cele\madf-8, Cele\madf-10, Cele\madf-2, Cele\madf-4, Cele\madf-9" - - - "visible,size defective,flightless" "wing hinge,wing blade,distal" FBgn0263087 CG43355 - http://flybase.org/reports/FBgn0263087 protein_coding_gene - - - "CG43355, chr2L:11486634..11486740" - CG43355 11-Aug-17 DroID_v2017_08 - - - - - Hsap\PRB1 FBgn0263399 CG43445 - http://flybase.org/reports/FBgn0263399 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43445 - CG43445 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022207 l(2)k04222b lethal (2) k04222b http://flybase.org/reports/FBgn0022207 - gene - - - l(2)k04222b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052521 CG32521 - http://flybase.org/reports/FBgn0052521 protein_coding_gene - - - "CG1735, CG1726, CG32521" - CG32521 11-Aug-17 DroID_v2017_08 - - Cele\col-103 - Mmus\Hoxa10 - "viable,fertile,visible,lethal - all die before end of pupal stage,some die during pupal stage" eye DRSC20550 I 0.021676317 -2.297563827 0.534901343 -0.400981107 -0.189883549 0.16270183 FBgn0029753 CG4198 - http://flybase.org/reports/FBgn0029753 protein_coding_gene - - - CG4198 - CG4198 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0027994 l(3)S126014 lethal (3) S126014 http://flybase.org/reports/FBgn0027994 gene - - - l(3)S126014 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037477 CG14610 - http://flybase.org/reports/FBgn0037477 protein_coding_gene - - - CG14610 - CG14610 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0283442 vas vasa http://flybase.org/reports/FBgn0283442 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 protein binding ; GO:0005515 | inferred from physical interaction with gus mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with piwi inferred from physical interaction with Fmr1 inferred from physical interaction with Dcr-1 RNA helicase activity ; GO:0003724 | traceable author statement RNA binding ; GO:0003723 | inferred from direct assay pole plasm assembly ; GO:0007315 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | traceable author statement intracellular mRNA localization ; GO:0008298 | traceable author statement oocyte anterior/posterior axis specification ; GO:0007314 | non-traceable author statement protein localization ; GO:0008104 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype regulation of translation ; GO:0006417 | traceable author statement regulation of oskar mRNA translation ; GO:0046011 | traceable author statement karyosome formation ; GO:0030717 | non-traceable author statement positive regulation of oskar mRNA translation ; GO:0046012 | non-traceable author statement pole plasm RNA localization ; GO:0007316 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement P granule ; GO:0043186 | traceable author statement perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay pole plasm ; GO:0045495 | inferred from direct assay spectrosome ; GO:0045170 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic ribonucleoprotein granule ; GO:0036464 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay "CG46283, BG:DS00929.14, vas, Vas, Vasa, VASA, CG43081, EP(2)0812, VAS, DmRH25, cgt, CG3506, vasa, fs(2)ltoRJ36" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG46283 11-Aug-17 DroID_v2017_08 Drer\ddx4 - "Cele\glh-1, Cele\glh-4, Cele\glh-3, Cele\glh-2" - Mmus\Ddx4 Hsap\DDX4 "lethal,maternal effect,grandchildless,recessive,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,female semi-sterile,male sterile,heat sensitive,non-enhancer of variegation,non-suppressor of variegation,sterile,partially,mitotic cell cycle defective,female,wild-type" "dorsal appendage,karyosome,pole granule,maternal effect,pole cell,embryonic abdominal segment,pole plasm,egg,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,embryonic/larval salivary gland,micropyle,egg chamber,oocyte,ovary,follicle cell,P granule,spermatocyte,abdominal segment,ectopic,chorion | maternal effect,germline cyst,female germline stem cell,cystocyte,germarium region 1,nurse cell,oocyte nucleus,stage S6 oocyte,stage S9 oocyte,stage S10 oocyte,synaptonemal complex,cystoblast" FBgn0040372 G9a G9a http://flybase.org/reports/FBgn0040372 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003606, InterPro:IPR007728 histone-lysine N-methyltransferase activity ; GO:0018024 | inferred from direct assay" positive regulation of histone H3-K9 dimethylation ; GO:1900111 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype histone H3-K9 methylation ; GO:0051567 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from genetic interaction with EcR nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay euchromatin ; GO:0000791 | colocalizes_with inferred from direct assay "dG9a, cab65850 G9a Dm, EG:BACR37P7.2, G9a, CG2995, EHMT" "IPR001214:SET domain, IPR002110:Ankyrin repeat, IPR007728:Pre-SET domain, IPR020683:Ankyrin repeat-containing domain" CG2995 11-Aug-17 DroID_v2017_08 "Drer\whsc1l1, Drer\suv39h1b, Drer\ehmt1b, Drer\suv39h1a, Drer\ehmt1a, Drer\ehmt2, Drer\myca, Drer\setmar" Scer\SET2 Cele\set-11 "Xtro\ehmt2, Xtro\ehmt1, Xtro\suv39h2" "Mmus\Suv39h1, Mmus\Setmar, Mmus\Whsc1l1, Mmus\Ehmt1, Mmus\Suv39h2, Mmus\Ehmt2" "Hsap\EHMT2, Hsap\EHMT1, Hsap\SUV39H1, Hsap\WHSC1L1, Hsap\SUV39H2, Hsap\SETMAR" "memory defective,viable,neuroanatomy defective,locomotor behavior defective,learning defective,fertile,non-suppressor of variegation,developmental rate defective,lethal - all die before end of P-stage,some die during pharate adult stage,visible,melanotic mass phenotype,lethal - all die before end of larval stage,some die during third instar larval stage" "ventral multidendritic neuron,multidendritic dendrite,wing vein,puparial operculum,wing" FBgn0065480 l(2)SH1284 lethal (2) SH1284 http://flybase.org/reports/FBgn0065480 gene - - - "l(2)SH1284, l(2)SH2 1284" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267723 CR46056 - http://flybase.org/reports/FBgn0267723 non_protein_coding_gene - - - CR46056 - CR46056 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038967 CG13847 - http://flybase.org/reports/FBgn0038967 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13847 - CG13847 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary" DRSC23172 K -1.104585369 -0.724132648 -0.7416529 -0.459395922 -0.734676971 2.531774788 FBgn0267550 CR45890 - http://flybase.org/reports/FBgn0267550 non_protein_coding_gene - - - CR45890 - CR45890 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039985 CG17474 - http://flybase.org/reports/FBgn0039985 protein_coding_gene - - - CG17474 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035802 Pura Puratrophin-1-like http://flybase.org/reports/FBgn0035802 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with RhoGEF4 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of locomotor rhythm ; GO:1904059 | inferred from genetic interaction with Rho1 positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with RhoGEF4 imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG7515, CG33167, CG7520, CG7511, CG7513, CG33275, Pura" "IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR011990:Tetratricopeptide-like helical domain" CG33275 11-Aug-17 DroID_v2017_08 "Drer\zgc:158766, Drer\kalrnb, Drer\arhgef40, Drer\plekhg4, Drer\quo, Drer\si:dkey-65j6.2, Drer\plekhn1, Drer\LOC101885278, Drer\arhgef25b" Scer\CDC24 - "Xtro\arhgef40, Xtro\kalrn" "Mmus\Arhgef40, Mmus\D630003M21Rik, Mmus\Plekhg4" "Hsap\PLEKHG4B, Hsap\KIAA1755, Hsap\ARHGEF40, Hsap\PLEKHG4" "viable,fertile" FBgn0037936 CG6908 - http://flybase.org/reports/FBgn0037936 protein_coding_gene - copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype - CG6908 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG6908 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\E02C12.9, Cele\H06H21.8, Cele\C29F7.1, Cele\F59B1.10, Cele\E02C12.8, Cele\F49C12.7, Cele\E02C12.10, Cele\T16G1.6, Cele\F59B1.8, Cele\H37A05.2, Cele\Y45G12C.4, Cele\nhr-246, Cele\dhs-27, Cele\E02C12.6, Cele\F56A4.5" - - - viable FBgn0011403 l(3)j7C3 lethal (3) j7C3 http://flybase.org/reports/FBgn0011403 - gene - - - l(3)j7C3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001175 hap hapless http://flybase.org/reports/FBgn0001175 - gene molecular_function ; GO:0003674 | no biological data available Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available hap - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0066116 Fol2 Follistatin-related 2 http://flybase.org/reports/FBgn0066116 gene - - - "dFol2, Fol2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051151 wge winged eye http://flybase.org/reports/FBgn0051151 protein_coding_gene transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 cell differentiation ; GO:0030154 | inferred from electronic annotation with InterPro:IPR029616 heterochromatin assembly ; GO:0031507 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 imaginal disc morphogenesis ; GO:0007560 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 chromatin silencing complex ; GO:0005677 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 chromatin ; GO:0000785 | inferred from direct assay "CG31151, CG4902, CG17621, wge" "IPR001025:Bromo adjacent homology (BAH) domain, IPR029616:Protein winged eye" CG31151 11-Aug-17 DroID_v2017_08 "Drer\LOC797750, Drer\bahcc1, Drer\tnrc18" - - "Xtro\tnrc18, Xtro\bahcc1" "Mmus\Bahcc1, Mmus\Tnrc18" "Hsap\BAHCC1, Hsap\TNRC18" FBgn0001454 l(1)7Dh lethal (1) 7Dh http://flybase.org/reports/FBgn0001454 - gene - - - l(1)7Dh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065859 l(2)SH0285 lethal (2) SH0285 http://flybase.org/reports/FBgn0065859 gene - - - "l(2)SH0285, l(2)SH2 0285" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004153 l(2)57Ag lethal (2) 57Ag http://flybase.org/reports/FBgn0004153 - gene - - - l(2)57Ag - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002533 Lcp2 Larval cuticle protein 2 http://flybase.org/reports/FBgn0002533 - protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from direct assay chitin-based cuticle development ; GO:0040003 | inferred from sequence model larval chitin-based cuticle development ; GO:0008363 | inferred by curator from GO:0008010 extracellular matrix ; GO:0031012 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from direct assay "CP2, L[[3]]CP2, LCP-2, 2, II, LCP2, CG8697, Lcp2, DmelLcp2, lcp2" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8697 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\H2-K1, Mmus\2410137M14Rik" - " larval stage | late third instar larval stage , larval stage | third instar stage 2 " " organism

, integumentary system

" "electrophoretic variant,viable" FBgn0060719 l(3)S068802 lethal (3) S068802 http://flybase.org/reports/FBgn0060719 gene - - - "0688/02, l(3)S068802" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0030834 CG8675 - http://flybase.org/reports/FBgn0030834 protein_coding_gene - - - CG8675 IPR019351:Protein of unknown function DUF2039 CG8675 11-Aug-17 DroID_v2017_08 Drer\zgc:101016 - - Xtro\c9orf85 Mmus\1110059E24Rik Hsap\C9orf85 viable FBgn0003399 shr shrunken http://flybase.org/reports/FBgn0003399 - gene - - - shr - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,small body,body color defective" FBgn0069946 CG41089 - http://flybase.org/reports/FBgn0069946 protein_coding_gene - - - CG41089 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015998 l(3)12E7 lethal (3) 12E7 http://flybase.org/reports/FBgn0015998 - gene - - - l(3)12E7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037675 HP1e Heterochromatin Protein 1e http://flybase.org/reports/FBgn0037675 protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with Su(var)205 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with HGNC:1555 "chromosome organization ; GO:0051276 | inferred from sequence or structural similarity with Su(var)205 mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype sperm chromatin condensation ; GO:0035092 | inferred from mutant phenotype positive regulation of chromatin silencing at telomere ; GO:0031940 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008251 nucleus ; GO:0005634 | inferred by curator from GO:0031940 chromatin ; GO:0000785 | inferred from sequence or structural similarity with Su(var)205 "CG8120, HP1e, HP1E" "IPR000953:Chromo/chromo shadow domain, IPR008251:Chromo shadow domain, IPR016197:Chromo domain-like, IPR023779:Chromo domain, conserved site, IPR023780:Chromo domain" CG8120 11-Aug-17 DroID_v2017_08 "Drer\cdyl, Drer\cbx3a, Drer\cbx1a, Drer\cbx5, Drer\cbx3b, Drer\cbx1b" - "Cele\hpl-2, Cele\set-31, Cele\H04D03.6, Cele\hpl-1" "Xtro\cbx5, Xtro\cbx3, Xtro\cbx1" "Mmus\Cbx1, Mmus\Cbx5, Mmus\Mphosph8, Mmus\Cdyl, Mmus\Cdyl2, Mmus\Cbx3" "Hsap\CDYL, Hsap\CBX5, Hsap\CBX1, Hsap\CDY1, Hsap\CDYL2, Hsap\CDY2B, Hsap\CDY2A, Hsap\MPHOSPH8, Hsap\CDY1B, Hsap\CBX3" viable FBgn0010031 E(Dl)KP254 Enhancer of Delta KP254 http://flybase.org/reports/FBgn0010031 - gene - - - E(Dl)KP254 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035782 CG14835 - http://flybase.org/reports/FBgn0035782 protein_coding_gene - - - CG14835 - CG14835 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0061356 CG18003 - http://flybase.org/reports/FBgn0061356 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR000262, InterPro:IPR008259, InterPro:IPR012133 FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR012133" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR008259, InterPro:IPR012133" peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:4809 inferred from sequence model "CG30019, CG18003" "IPR000262:FMN-dependent dehydrogenase, IPR008259:FMN-dependent alpha-hydroxy acid dehydrogenase, active site, IPR012133:Alpha-hydroxy acid dehydrogenase, FMN-dependent, IPR013785:Aldolase-type TIM barrel" CG18003 11-Aug-17 DroID_v2017_08 "Drer\hao1, Drer\hao2" Scer\CYB2 Cele\F41E6.5 "Xtro\hao1, Xtro\hao2" "Mmus\Carns1, Mmus\Hao2, Mmus\Hao1" "Hsap\HAO2, Hsap\HAO1, Hsap\CARNS1" "viable,fertile" FBgn0013704 mt:tRNA:Arg-TCG mitochondrial transfer RNA:Arginine-TCG http://flybase.org/reports/FBgn0013704 FBgn0002867 tRNA_gene - - - "CR34078, Arg-maxi, tRNA[Arg], mtdbD00006303, mt:tRNA:Arg-TCG, mt:tRNA:R" - CR34078 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011580 Dlw Dorsal wing http://flybase.org/reports/FBgn0011580 - gene molecular_function ; GO:0003674 | no biological data available wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Dlw - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,somatic clone,dominant,lethal - all die before end of larval stage,some die during larval stage" "wing,somatic clone,mesothoracic tergum & macrochaeta | somatic clone,macrochaeta,dorsal,ventral compartment" FBgn0051112 CG31112 - http://flybase.org/reports/FBgn0051112 protein_coding_gene - - - CG31112 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025344 anon-17Ac anon-17Ac http://flybase.org/reports/FBgn0025344 - gene - - - anon-17Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061152 l(2)J73 lethal (2) J73 http://flybase.org/reports/FBgn0061152 gene - - - "J73, l(2)J73" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262205 mir-932 mir-932 stem loop http://flybase.org/reports/FBgn0262205 miRNA_gene - regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype - "dme-mir-932, miR-932, mir-932, MIR-932, CR42912, dme-miR-932" - CR42912 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "eye,wing,wing blade" FBgn0065386 l(2)SH1636 lethal (2) SH1636 http://flybase.org/reports/FBgn0065386 gene - - - "l(2)SH1636, l(2)SH2 1636" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261921 CG8176::EndoA - http://flybase.org/reports/FBgn0261921 engineered_fusion_gene - - - "CG8176::endoA, CG8176::EndoA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030170 CG2990 - http://flybase.org/reports/FBgn0030170 protein_coding_gene 5'-flap endonuclease activity ; GO:0017108 | inferred from electronic annotation with InterPro:IPR026851 single-stranded DNA-dependent ATPase activity ; GO:0043142 | inferred from electronic annotation with InterPro:IPR026851 "DNA replication, Okazaki fragment processing ; GO:0033567 | inferred from electronic annotation with InterPro:IPR026851" - CG2990 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014808:DNA replication factor Dna2, N-terminal, IPR026851:Dna2" CG2990 11-Aug-17 DroID_v2017_08 Drer\dna2 Scer\DNA2 Cele\dna-2 Xtro\dna2 Mmus\Dna2 Hsap\DNA2 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0063417 l(3)3450-F lethal (3) 3450-F http://flybase.org/reports/FBgn0063417 gene - - - l(3)3450-F - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0267138 CR45578 - http://flybase.org/reports/FBgn0267138 non_protein_coding_gene - - - CR45578 - CR45578 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066111 su(f)::Hsap\CSTF3 CSTF3 http://flybase.org/reports/FBgn0066111 engineered_fusion_gene - - - "Hsap\CSTF3::su(f), su(f)::Hsap\CSTF3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260119 2L4117 - http://flybase.org/reports/FBgn0260119 gene - "lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype" - 2L4117 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0026638 l(2)k11006 lethal (2) k11006 http://flybase.org/reports/FBgn0026638 - gene - - - l(2)k11006 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266863 CR45324 - http://flybase.org/reports/FBgn0266863 non_protein_coding_gene - - - CR45324 - CR45324 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085791 CR41508 - http://flybase.org/reports/FBgn0085791 pseudogene_attribute - - - CR41508 - CR41508 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042118 Cpr65Ax2 Cuticular protein 65Ax2 http://flybase.org/reports/FBgn0042118 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:RE62456, Cpr65Ax2, CG18777, DmelCpr65Ax2" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG18777 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0039743 CG7946 - http://flybase.org/reports/FBgn0039743 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG7946 "IPR000313:PWWP domain, IPR021567:Lens epithelium-derived growth factor (LEDGF)" CG7946 11-Aug-17 DroID_v2017_08 "Drer\hdgfrp3, Drer\si:ch211-116m6.3, Drer\hdgfrp2, Drer\psip1" "Scer\PDP3, Scer\IOC4" Cele\C06A5.3 "Xtro\psip1, Xtro\hdgfrp2, Xtro\hdgf, Xtro\hdgfrp3" "Mmus\Hdgfrp2, Mmus\Hdgfrp3, Mmus\Hdgf, Mmus\Hdgfl1, Mmus\Psip1" "Hsap\PSIP1, Hsap\HDGFRP2, Hsap\HDGFRP3, Hsap\HDGF, Hsap\HDGFL1" "viable,female fertile" FBgn0038353 CG5399 - http://flybase.org/reports/FBgn0038353 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5399 IPR012674:Calycin CG5399 11-Aug-17 DroID_v2017_08 - - - - - - DRSC15791 I 2.077510487 -1.682918453 0.784730096 -0.45022926 -0.423011268 -0.362055339 FBgn0037338 Snm1 Snm1 http://flybase.org/reports/FBgn0037338 protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000581728 5'-3' exodeoxyribonuclease activity ; GO:0035312 | inferred from biological aspect of ancestor with PANTHER:PTN000581728 interstrand cross-link repair ; GO:0036297 | inferred from biological aspect of ancestor with PANTHER:PTN000581728 double-strand break repair via nonhomologous end joining ; GO:0006303 | inferred from biological aspect of ancestor with PANTHER:PTN000581728 protection from non-homologous end joining at telomere ; GO:0031848 | inferred from biological aspect of ancestor with PANTHER:PTN000581728 "nuclear chromosome, telomeric region ; GO:0000784 | inferred from biological aspect of ancestor with PANTHER:PTN000581728" "mus322, SNM1, CG10018, Snm1" "IPR011084:DNA repair metallo-beta-lactamase, IPR001279:Metallo-beta-lactamase" CG10018 11-Aug-17 DroID_v2017_08 "Drer\dclre1a, Drer\dclre1b, Drer\dclre1c" Scer\PSO2 Cele\mrt-1 "Xtro\dclre1b, Xtro\dclre1c" "Mmus\Dclre1c, Mmus\Dclre1a, Mmus\Dclre1b" "Hsap\DCLRE1C, Hsap\DCLRE1B, Hsap\DCLRE1A" "viable,chemical sensitive" FBgn0050160 CG30160 - http://flybase.org/reports/FBgn0050160 protein_coding_gene - - "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000301, InterPro:IPR008952, InterPro:IPR018499" CG30160 "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG30160 11-Aug-17 DroID_v2017_08 "Drer\cd63, Drer\zgc:171713" - "Cele\tsp-7, Cele\tsp-2, Cele\tsp-14, Cele\tsp-3, Cele\tsp-1" Xtro\cd63 Mmus\Cd63 Hsap\CD63 DRSC04961 I 1.646148338 0.310735068 1.031219393 -0.517580823 0.2887113 -1.347242236 FBgn0266167 CR44873 - http://flybase.org/reports/FBgn0266167 non_protein_coding_gene - - - CR44873 - CR44873 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065621 l(2)SH0804 lethal (2) SH0804 http://flybase.org/reports/FBgn0065621 gene - - - "l(2)SH0804, l(2)SH2 0804" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005496 l(1)tsSD19 lethal (1) tsSD19 http://flybase.org/reports/FBgn0005496 - gene - - - l(1)tsSD19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0085436 Not1 Not1 http://flybase.org/reports/FBgn0085436 protein_coding_gene protein complex scaffold ; GO:0032947 | inferred from biological aspect of ancestor with PANTHER:PTN000322838 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 poly(A)-specific ribonuclease activity ; GO:0004535 | inferred from direct assay "negative regulation of translation ; GO:0017148 | inferred from biological aspect of ancestor with PANTHER:PTN000322838 neurogenesis ; GO:0022008 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | inferred from biological aspect of ancestor with PANTHER:PTN000322838 muscle organ development ; GO:0007517 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from direct assay nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs negative regulation of translation ; GO:0017148 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000322838 CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000322838 CCR4-NOT complex ; GO:0030014 | inferred from direct assay "CG34407, CG1884, NOT, NOT1, clone 1.29, anon-WO0118547.221, anon-EST:Liang-1.29, Not1, CG1874, not1" "IPR007196:CCR4-Not complex component, Not1, C-terminal, IPR024557:CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819, IPR011989:Armadillo-like helical, IPR032191:CCR4-NOT transcription complex subunit 1, CAF1-binding domain, IPR032194:CCR4-NOT transcription complex subunit 1, HEAT repeat, IPR032193:CCR4-NOT transcription complex subunit 1, TTP binding domain" CG34407 11-Aug-17 DroID_v2017_08 Drer\cnot1 Scer\CDC39 Cele\let-711 Xtro\cnot1 Mmus\Cnot1 Hsap\CNOT1 "visible,lethal,neuroanatomy defective" "wing vein,ectopic,wing,eye,embryonic/larval neuroblast,ganglion mother cell" DRSC06787 IEK 1.611823337 -1.971264058 -3.275680596 -4.408509334 2.656337605 2.313634322 FBgn0039697 CG7834 - http://flybase.org/reports/FBgn0039697 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with UniProtKB:P38117 electron carrier activity ; GO:0009055 | inferred from biological aspect of ancestor with PANTHER:PTN000480317 oxidative phosphorylation ; GO:0006119 | inferred from sequence or structural similarity with UniProtKB:P13803 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype oxidation-reduction process ; GO:0055114 | inferred from biological aspect of ancestor with PANTHER:PTN000480317 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000480375 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial electron transfer flavoprotein complex ; GO:0017133 | inferred from sequence or structural similarity with UniProtKB:P38117 "CG7834, CG 7834, ETFB" "IPR000049:Electron transfer flavoprotein, beta-subunit, conserved site, IPR012255:Electron transfer flavoprotein, beta subunit, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR014730:Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, IPR033948:Electron transfer flavoprotein, beta subunit, N-terminal" CG7834 11-Aug-17 DroID_v2017_08 Drer\etfb Scer\CIR1 Cele\F23C8.5 Xtro\etfb Mmus\Etfb Hsap\ETFB "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0043993 Su(rst)D231 Su(rst)D231 http://flybase.org/reports/FBgn0043993 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D231, Su(rst)D231" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051716 Cnot4 CCR4-NOT transcription complex subunit 4 http://flybase.org/reports/FBgn0051716 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000000870 ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN000288208 zinc ion binding ; GO:0008270 | inferred from sequence model mRNA binding ; GO:0003729 | inferred from sequence or structural similarity protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000000870 regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype CCR4-NOT complex ; GO:0030014 | inferred from biological aspect of ancestor with PANTHER:PTN000288208 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000870 "NOT4, CG5251, cg5251, CG5244, CG31716, Not4, Cnot4, Cont4, Q8IPB9_DROME, not4" "IPR000504:RNA recognition motif domain, IPR001841:Zinc finger, RING-type, IPR000571:Zinc finger, CCCH-type, IPR034261:CNOT4, RNA recognition motif, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR003954:RNA recognition motif domain, eukaryote" CG31716 11-Aug-17 DroID_v2017_08 "Drer\cnot4a, Drer\cnot4b" Scer\MOT2 Cele\ntl-4 Xtro\cnot4 Mmus\Cnot4 Hsap\CNOT4 "viable,fertile" DRSC02831 K 0.508440888 -0.254914402 0.258938133 0.152073587 2.710025203 1.194609827 FBgn0051892 tRNA:Asp-GTC-1-3 transfer RNA:Aspartic acid-GTC 1-3 http://flybase.org/reports/FBgn0051892 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "AE002690.trna22-AspGTC, tRNA:asp2:29D, tRNA:D2:29D, tRNA:D:GTC:AE002690-f, CR31892, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna32-AspGTC, tRNA:Asp-GTC-1-3, tRNA:CR31892, tRNA-Asp-GTC-1-3, GAC" - CR31892 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001505 l(1)10Dc lethal (1) 10Dc http://flybase.org/reports/FBgn0001505 - gene - - - l(1)10Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011672 Mvl Malvolio http://flybase.org/reports/FBgn0011672 - protein_coding_gene "manganese ion transmembrane transporter activity ; GO:0005384 | inferred from mutant phenotype symporter activity ; GO:0015293 | inferred from genetic interaction with SGD:S000001092,SGD:S000004024,SGD:S000005482 copper ion transmembrane transporter activity ; GO:0005375 | inferred from mutant phenotype iron ion transmembrane transporter activity ; GO:0005381 | inferred from mutant phenotype" "transition metal ion homeostasis ; GO:0055076 | inferred from mutant phenotype iron assimilation ; GO:0033212 | inferred from direct assay copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype multicellular organismal iron ion homeostasis ; GO:0060586 | inferred from direct assay sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype divalent metal ion transport ; GO:0070838 | inferred from genetic interaction with SGD:S000001092,SGD:S000004024,SGD:S000005482 viral entry into host cell ; GO:0046718 | inferred from mutant phenotype copper ion import ; GO:0015677 | inferred from mutant phenotype transition metal ion transport ; GO:0000041 | inferred from mutant phenotype positive regulation of iron ion transmembrane transport ; GO:0034761 | inferred from mutant phenotype" endosome ; GO:0005768 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay "mvl, NRM2, CG3671, Mvl, DMT1, dNRAMP" IPR001046:NRAMP family CG3671 11-Aug-17 DroID_v2017_08 Drer\slc11a2 "Scer\SMF3, Scer\SMF1, Scer\SMF2" "Cele\smf-2, Cele\smf-3, Cele\smf-1" "Xtro\slc11a1, Xtro\slc11a2" "Mmus\Slc11a1, Mmus\Slc11a2" "Hsap\SLC11A1, Hsap\SLC11A2" " embryonic stage | stage 16 , embryonic stage -- adult stage , embryonic stage | stage 10 " " antenno-maxillary complex

, procephalic segment

, tracheal pit | vicinity

, amnioserosa

" "lethal,recessive,behavior defective,semidominant,taste perception defective,conditional,partially lethal - majority die,female limited,chemical sensitive,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0264696 CG43965 - http://flybase.org/reports/FBgn0264696 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43965 - CG43965 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032018 CG7806 - http://flybase.org/reports/FBgn0032018 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011527 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 "Dme_CG7806, CG7806" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG7806 11-Aug-17 DroID_v2017_08 "Drer\abcc2, Drer\abcc10, Drer\abcc1, Drer\abcc8, Drer\abcc9, Drer\LOC100329706, Drer\cftr, Drer\abcc3, Drer\abcc6a, Drer\abcc5, Drer\abcc6b.2, Drer\abcc13, Drer\abcc4, Drer\abcc12" "Scer\YBT1, Scer\NFT1, Scer\VMR1, Scer\YKR104W, Scer\YOR1, Scer\BPT1, Scer\YCF1" "Cele\mrp-8, Cele\mrp-4, Cele\mrp-7, Cele\mrp-1, Cele\mrp-6, Cele\mrp-3, Cele\mrp-2, Cele\mrp-5" "Xtro\abcc10, Xtro\abcc1, Xtro\abcc4, Xtro\abcc6, Xtro\abcc3, Xtro\cftr" "Mmus\Abcc8, Mmus\Abcc9, Mmus\Abcc2, Mmus\Abcc6, Mmus\Cftr, Mmus\Abcc3, Mmus\Abcc5, Mmus\Abcc4, Mmus\Abcc1, Mmus\Abcc12, Mmus\Abcc10" "Hsap\ABCC6, Hsap\ABCC3, Hsap\ABCC9, Hsap\ABCC12, Hsap\ABCC2, Hsap\ABCC10, Hsap\ABCC5, Hsap\ABCC1, Hsap\ABCC8, Hsap\ABCC4, Hsap\ABCC11, Hsap\CFTR" "viable,fertile" FBgn0003034 SP Sex Peptide http://flybase.org/reports/FBgn0003034 FBgn0010084 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR012608 G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with SPR hormone activity ; GO:0005179 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O97148 "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern regulation of post-mating oviposition ; GO:0048042 | inferred from direct assay negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype negative regulation of female receptivity ; GO:0007621 | traceable author statement post-mating behavior ; GO:0045297 | traceable author statement negative regulation of female receptivity, post-mating ; GO:0045434 | traceable author statement regulation of post-mating oviposition ; GO:0048042 | traceable author statement regulation of oviposition ; GO:0046662 | traceable author statement negative regulation of female receptivity ; GO:0007621 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay juvenile hormone biosynthetic process ; GO:0006718 | non-traceable author statement oviposition ; GO:0018991 | traceable author statement regulation of female receptivity, post-mating ; GO:0046008 | inferred from mutant phenotype regulation of juvenile hormone biosynthetic process ; GO:0007557 | traceable author statement adult feeding behavior ; GO:0008343 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | traceable author statement "SP, ACP, Acp70, Spg70, PapB, CG17673, Acp70A, Acp70a, DrmSP, Acp-70A, Apc70A, Sex Peptide, ACP70A, sex peptide, mSP" IPR012608:Sex peptide CG17673 11-Aug-17 DroID_v2017_08 - - - - - - "mating behavior defective,virgin female limited,lethal,female,courtship behavior defective,feeding behavior defective,female limited,behavior defective,mated female limited" spermatozoon FBgn0063409 l(3)3450-N lethal (3) 3450-N http://flybase.org/reports/FBgn0063409 gene - - - l(3)3450-N - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0040748 CG13943 - http://flybase.org/reports/FBgn0040748 protein_coding_gene - - - CG13943 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014171 fs(3)83Ba fs(3)83Ba http://flybase.org/reports/FBgn0014171 - gene - - - fs(3)83Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "dorsal appendage,nurse cell,egg" FBgn0004199 l(3)84Da lethal (3) 84Da http://flybase.org/reports/FBgn0004199 - gene - - - l(3)84Da - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039280 Mocs2 Molybdenum cofactor synthesis 2 http://flybase.org/reports/FBgn0039280 protein_coding_gene molybdopterin synthase activity ; GO:0030366 | inferred from sequence or structural similarity with UniProtKB:O96007 molybdopterin synthase activity ; GO:0030366 | inferred from sequence or structural similarity with HGNC:7193 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay molybdopterin synthase activity ; GO:0030366 | inferred from biological aspect of ancestor with PANTHER:PTN000600812 molybdopterin cofactor biosynthetic process ; GO:0032324 | inferred from biological aspect of ancestor with PANTHER:PTN000600812 chromatin remodeling ; GO:0006338 | inferred from direct assay Mo-molybdopterin cofactor biosynthetic process ; GO:0006777 | inferred from sequence or structural similarity with HGNC:7193 histone acetylation ; GO:0016573 | inferred from direct assay Mo-molybdopterin cofactor biosynthetic process ; GO:0006777 | inferred from sequence or structural similarity with UniProtKB:O96007 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000600812 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:O96007 molybdopterin synthase complex ; GO:0019008 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from physical interaction with Ada2a Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay "Mocs2, CG10238, Dromel_CG10238_FBtr0084782_mocs_mORF, MOCS2, dMoaE, MBIP/dMoaE, Mbip" "IPR003448:Molybdopterin biosynthesis MoaE, IPR028888:Molybdopterin synthase catalytic subunit, eukaryotes" CG10238 11-Aug-17 DroID_v2017_08 "Drer\nmrk2, Drer\nmrk1, Drer\LOC103911725" Scer\NRK1 Cele\T27A3.6 "Xtro\mocs2, Xtro\mbip, Xtro\nmrk2" "Mmus\Mbip, Mmus\Nmrk2, Mmus\Mocs2, Mmus\Nmrk1" "Hsap\NMRK1, Hsap\NMRK2, Hsap\MBIP, Hsap\MOCS2" viable FBgn0038236 Cyp313a1 Cyp313a1 http://flybase.org/reports/FBgn0038236 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" - "313a1p, 313a1, Cyp313a1p, CG3360, Cyp313a1, Cyp313a, Cyp313A1, CYP313a1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG3360 11-Aug-17 DroID_v2017_08 "Drer\cyp46a1.3, Drer\cyp4f3, Drer\cyp26b1, Drer\zgc:123299, Drer\cyp46a1.1, Drer\LOC100329425, Drer\cyp46a1.2, Drer\cyp26a1, Drer\cyp46a1.4, Drer\cyp20a1, Drer\cyp19a1a, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp4t8, Drer\cyp26c1, Drer\cyp19a1b" "Scer\ERG5, Scer\ERG11, Scer\DIT2" "Cele\cyp-25A2, Cele\cyp-25A1" "Xtro\cyp4b1, Xtro\mgc108213, Xtro\cyp4v2, Xtro\cyp26b1, Xtro\cyp20a1, Xtro\cyp26c1, Xtro\cyp4f22, Xtro\cyp19a1, Xtro\cyp26a1, Xtro\cyp4b1.2, Xtro\LOC100488227, Xtro\cyp4f2, Xtro\LOC100487918" "Mmus\Cyp4a14, Mmus\Cyp4a12b, Mmus\Cyp4f40, Mmus\Cyp4f15, Mmus\Cyp20a1, Mmus\Cyp46a1, Mmus\Cyp4f16, Mmus\Cyp4x1, Mmus\Cyp4f13, Mmus\Cyp26c1, Mmus\Cyp4f39, Mmus\Cyp4f18, Mmus\Cyp4a32, Mmus\Cyp4f37, Mmus\Cyp4b1, Mmus\Cyp26b1, Mmus\Cyp4f17, Mmus\Cyp4v3, Mmus\Cyp4a10, Mmus\Cyp19a1, Mmus\Cyp4a12a, Mmus\Cyp4a31, Mmus\Cyp26a1, Mmus\Cyp4f14" "Hsap\CYP4X1, Hsap\CYP26A1, Hsap\CYP4Z1, Hsap\CYP26C1, Hsap\CYP46A1, Hsap\CYP19A1, Hsap\CYP20A1, Hsap\CYP26B1, Hsap\CYP4A22, Hsap\CYP4F22, Hsap\CYP4F2, Hsap\CYP4F12, Hsap\CYP4F11, Hsap\CYP4A11, Hsap\CYP4V2, Hsap\CYP4F3, Hsap\CYP4B1" viable DRSC16624 K 0.185306243 0.776872943 0.332012511 0.214795089 -0.08819302 -1.625350741 FBgn0064164 l(3)S007631 lethal (3) S007631 http://flybase.org/reports/FBgn0064164 gene - - - l(3)S007631 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0003576 Su(S) Suppressor of Star http://flybase.org/reports/FBgn0003576 - gene - - - "Su(S), su(s)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066346 l(3)99DEi lethal (3) 99DEi http://flybase.org/reports/FBgn0066346 gene - - - l(3)99DEi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004614 Adv Additional veins http://flybase.org/reports/FBgn0004614 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Adv - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "wing vein,wing vein L1,wing vein L3,wing vein L2,ectopic" FBgn0035237 CG13917 - http://flybase.org/reports/FBgn0035237 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 CG13917 "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain" CG13917 11-Aug-17 DroID_v2017_08 Drer\si:ch73-389b16.2 - - - Mmus\Btbd8 Hsap\BTBD8 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0061146 l(3)S000122b lethal (3) S000122b http://flybase.org/reports/FBgn0061146 gene - - - "0001/22, l(3)S000122b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031314 IntS14 Integrator 14 http://flybase.org/reports/FBgn0031314 protein_coding_gene - snRNA 3'-end processing ; GO:0034472 | inferred from direct assay integrator complex ; GO:0032039 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG4785, Q9VPY0, IntS14" "IPR002035:von Willebrand factor, type A" CG4785 11-Aug-17 DroID_v2017_08 "Drer\vwa9, Drer\dnajc2" - Cele\dnj-11 "Xtro\vwa9, Xtro\dnajc2" "Mmus\Vwa9, Mmus\Dnajc2" "Hsap\DNAJC2, Hsap\VWA9" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035424 CG11505 - http://flybase.org/reports/FBgn0035424 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11505 "IPR006630:RNA-binding protein Lupus La, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR000504:RNA recognition motif domain" CG11505 11-Aug-17 DroID_v2017_08 "Drer\larp4aa, Drer\larp4ab, Drer\larp4b" "Scer\SLF1, Scer\SRO9, Scer\LHP1" "Cele\larp-1, Cele\larp-5" "Xtro\larp4, Xtro\larp4b" "Mmus\Larp4b, Mmus\Larp4" "Hsap\LARP4, Hsap\LARP4B" "viable,fertile,lethal" FBgn0005419 l(1)adl8 lethal (1) adl8 http://flybase.org/reports/FBgn0005419 - gene - - - "l(1)adl-8, l(1)adl8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,heat sensitive,partially lethal - majority die,lethal" FBgn0265613 CR44431 - http://flybase.org/reports/FBgn0265613 non_protein_coding_gene - - - CR44431 - CR44431 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032797 Hasp Hig-anchoring scaffold protein http://flybase.org/reports/FBgn0032797 protein_coding_gene peptidase inhibitor activity ; GO:0030414 | inferred from electronic annotation with InterPro:IPR008197 - synaptic cleft ; GO:0043083 | inferred from direct assay "CT28647, anon-EST:Posey189, Hasp, CG10186, hasp" "IPR000436:Sushi/SCR/CCP domain, IPR007110:Immunoglobulin-like domain, IPR008197:WAP-type 'four-disulfide core' domain, IPR013783:Immunoglobulin-like fold" CG10186 11-Aug-17 DroID_v2017_08 "Drer\rca2.1, Drer\susd4, Drer\cfhl2, Drer\si:ch73-217n20.1, Drer\cfhl1, Drer\cfh, Drer\sele, Drer\im:7151449, Drer\rca2.2, Drer\si:ch211-233f16.1, Drer\csmd2" - "Cele\F36H2.3, Cele\T07H6.4, Cele\lev-9" "Xtro\f13b, Xtro\cfh" "Mmus\Csmd2, Mmus\Svep1, Mmus\Csmd3, Mmus\Csmd1, Mmus\Cfhr2, Mmus\Susd4, Mmus\F13b, Mmus\Gm4788, Mmus\Sele, Mmus\Cr1l, Mmus\Cr2, Mmus\Cfh, Mmus\Cfhr1, Mmus\Cd46" "Hsap\CD46, Hsap\CSMD2, Hsap\CFH, Hsap\SVEP1, Hsap\C4BPB, Hsap\CFHR4, Hsap\CFHR1, Hsap\CFHR2, Hsap\CSMD1, Hsap\SELE, Hsap\CR1, Hsap\CFHR3, Hsap\CFHR5, Hsap\SUSD4, Hsap\F13B, Hsap\CSMD3" viable FBgn0060572 l(3)S095812b lethal (3) S095812b http://flybase.org/reports/FBgn0060572 gene - - - "0958/12, l(3)S095812b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0031860 CG11236 - http://flybase.org/reports/FBgn0031860 protein_coding_gene "D-amino-acid oxidase activity ; GO:0003884 | inferred from electronic annotation with InterPro:IPR006181, InterPro:IPR023209 FAD binding ; GO:0071949 | inferred from electronic annotation with InterPro:IPR023209" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR006181 D-amino acid metabolic process ; GO:0046416 | inferred from electronic annotation with InterPro:IPR023209" peroxisome ; GO:0005777 | inferred from sequence model CG11236 "IPR006076:FAD dependent oxidoreductase, IPR006181:D-amino acid oxidase, conserved site, IPR023209:D-amino-acid oxidase" CG11236 11-Aug-17 DroID_v2017_08 "Drer\dao.1, Drer\dao.3, Drer\dao.2, Drer\zgc:172341" - "Cele\ddo-2, Cele\ddo-1, Cele\daao-1, Cele\ddo-3" "Xtro\ddo, Xtro\dao" "Mmus\Dao, Mmus\Ddo" "Hsap\DDO, Hsap\DAO, Hsap\METTL24" viable FBgn0020609 alf aloof http://flybase.org/reports/FBgn0020609 - gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype axonal fasciculation ; GO:0007413 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available alf - - 11-Aug-17 DroID_v2017_08 - - - - - - "Bolwig organ,Bolwig nerve" FBgn0067782 att-ORFB alternative testis transcripts open reading frame B http://flybase.org/reports/FBgn0067782 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "att, CG33488, att-ORFB" - CG33488 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033950 CG12862 - http://flybase.org/reports/FBgn0033950 protein_coding_gene - - - CG12862 IPR031750:Domain of unknown function DUF4734 CG12862 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266284 Ns3 Nucleostemin 3 http://flybase.org/reports/FBgn0266284 protein_coding_gene GTP binding ; GO:0005525 | inferred from sequence or structural similarity with UniProtKB:Q9H089 GTPase activity ; GO:0003924 | inferred from direct assay ribosomal subunit export from nucleus ; GO:0000054 | inferred from mutant phenotype regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype nuclear export ; GO:0051168 | inferred from sequence or structural similarity with UniProtKB:Q9H089 cellular response to starvation ; GO:0009267 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q9H089 Cajal body ; GO:0015030 | inferred from sequence or structural similarity with UniProtKB:Q9H089 "CG14788, ns3, l(1)2Ad, Ns3, l(1)G0431, BACN32G11.5, EG:BACN32G11.5, dNS3, dmNuc3, l(1)BA11, A60" "IPR030378:Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR006073:GTP binding domain, IPR023179:GTP-binding protein, orthogonal bundle domain" CG14788 11-Aug-17 DroID_v2017_08 "Drer\lsg1, Drer\gnl1" "Scer\GEP3, Scer\LSG1" Cele\C53H9.2 "Xtro\gnl1, Xtro\lsg1" "Mmus\Gnl1, Mmus\Lsg1" "Hsap\GNL1, Hsap\LSG1" FBgn0019742 l(1)8e3-43 lethal (1) 8e3-43 http://flybase.org/reports/FBgn0019742 - gene - - - l(1)8e3-43 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010873 l(3)05697 lethal (3) 05697 http://flybase.org/reports/FBgn0010873 - gene - - - l(3)05697 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025798 Su(var)1301 Suppressor of variegation 1301 http://flybase.org/reports/FBgn0025798 - gene - - - "Su-var(2), Su(var)1301" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015278 Pi3K68D Phosphotidylinositol 3 kinase 68D http://flybase.org/reports/FBgn0015278 FBgn0047208 protein_coding_gene "phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 phospholipid binding ; GO:0005543 | inferred from direct assay Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab21 1-phosphatidylinositol-4-phosphate 3-kinase activity ; GO:0035005 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Sbf 1-phosphatidylinositol-3-kinase activity ; GO:0016303 | inferred from direct assay phosphatidylinositol-4,5-bisphosphate 3-kinase activity ; GO:0046934 | NOT inferred from direct assay phosphatidylinositol 3-kinase activity ; GO:0035004 | non-traceable author statement phosphatidylinositol 3-kinase activity ; GO:0035004 | inferred from direct assay 1-phosphatidylinositol-3-kinase activity ; GO:0016303 | inferred from sequence or structural similarity with EMBL:Y13367 1-phosphatidylinositol-4-phosphate 3-kinase activity ; GO:0035005 | inferred from sequence or structural similarity with EMBL:Y13367" phosphatidylinositol-mediated signaling ; GO:0048015 | inferred from electronic annotation with InterPro:IPR015433 phagocytosis ; GO:0006909 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype phosphatidylinositol phosphorylation ; GO:0046854 | non-traceable author statement phosphatidylinositol phosphorylation ; GO:0046854 | inferred from sequence or structural similarity with EMBL:Y13367 phosphatidylinositol phosphorylation ; GO:0046854 | inferred from direct assay cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000005674 endosome membrane ; GO:0010008 | inferred from direct assay phosphatidylinositol 3-kinase complex ; GO:0005942 | inferred from biological aspect of ancestor with PANTHER:PTN000005674 "PI3K68D, Pi3K, PI3K, dPI3K, PI3K_68D, CG11621, PI(3)K, cpk, PI3K 68D, PI3K-68D/E, Cpk, PI3K 68_D, PI3K-68D, dPIK, BcDNA:LD15217, Pi3K68D, PI[[3]]K, 11621, pi3k68d, dPI3k" "IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR000008:C2 domain, IPR000341:Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR001263:Phosphoinositide 3-kinase, accessory (PIK) domain, IPR001683:Phox homologous domain, IPR002420:Phosphatidylinositol 3-kinase, C2 domain, IPR011009:Protein kinase-like domain, IPR015433:Phosphatidylinositol kinase, IPR016024:Armadillo-type fold, IPR029071:Ubiquitin-related domain" CG11621 11-Aug-17 DroID_v2017_08 "Drer\pik3c2g, Drer\pik3c2b, Drer\pik3c2a" Scer\VPS34 "Cele\age-1, Cele\piki-1" Xtro\pik3c2a "Mmus\Pik3c2a, Mmus\Pik3c2g, Mmus\Pik3c2b" "Hsap\PIK3C2B, Hsap\PIK3C2G, Hsap\PIK3C2A" larval stage--adult stage "visible,partially lethal - majority die,some die during pupal stage" "wing,scutellum,scutellar bristle,wing basal cell 1,proximal,haltere,wing vein,ectopic,wing margin,chaeta,supernumerary,sensillum campaniformium,embryonic/larval hemocyte,macrophage" FBgn0051087 CG31087 - http://flybase.org/reports/FBgn0051087 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG10551, CG31087" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31087 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.8, Cele\nhr-246, Cele\F20D6.5, Cele\D1044.1, Cele\C29F7.1, Cele\dhs-27, Cele\H06H21.8, Cele\C29F7.2, Cele\F59B1.10" - - - "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell" DRSC14253 I 1.726659438 -0.110506557 0.093540046 0.225407553 -0.119012126 -0.005958847 FBgn0005475 l(1)ts1006 lethal (1) ts1006 http://flybase.org/reports/FBgn0005475 - gene - - - l(1)ts1006 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0065085 snmRNA:705 small non-messenger RNA 705 http://flybase.org/reports/FBgn0065085 non_protein_coding_gene - - - "Dm-705, snmRNA:705" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086538 MRE6 mRNA-like ncRNA in embryogenesis 6 http://flybase.org/reports/FBgn0086538 non_protein_coding_gene - - - "MRE6, GM04458" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266347 nAChRalpha4 nicotinic Acetylcholine Receptor alpha4 http://flybase.org/reports/FBgn0266347 protein_coding_gene acetylcholine-gated cation channel activity ; GO:0022848 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine receptor activity ; GO:0015464 | contributes_to inferred from direct assay acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006029, InterPro:IPR006201 sleep ; GO:0030431 | inferred from mutant phenotype" postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity acetylcholine-gated channel complex ; GO:0005892 | inferred from direct assay "nAcRalpha-80B, CG12414, rye, Dalpha4, nAChRalpha4, nAChR, nAcRalpha-4, nAcRalpha-80, nAcRaplha-80B, CG17552, anon-WO0138359.1, nAChR-alpha80B" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG12414 11-Aug-17 DroID_v2017_08 "Drer\htr3a, Drer\chrnb1, Drer\chrnb2a, Drer\chrne, Drer\LOC798522, Drer\chrna2b, Drer\LOC101882451, Drer\chrna5, Drer\chrng, Drer\htr3b, Drer\chrna6, Drer\chrna3, Drer\chrna2a, Drer\si:ch211-39a7.1, Drer\chrna4b, Drer\si:ch211-256e16.4, Drer\chrnd, Drer\chrnb3b, Drer\chrnb1l, Drer\chrna9, Drer\chrnb4, Drer\chrnb2b, Drer\chrnb3a, Drer\chrna1, Drer\chrnb2l, Drer\si:ch73-380n15.2, Drer\chrna10a" - "Cele\acr-7, Cele\acr-2, Cele\acr-21, Cele\acr-16, Cele\acr-12, Cele\lgc-4, Cele\acr-15, Cele\unc-38, Cele\acr-8, Cele\unc-63, Cele\lev-1, Cele\lev-8, Cele\acr-14, Cele\acr-25, Cele\acr-19, Cele\eat-2, Cele\acr-6, Cele\acr-3, Cele\acr-9, Cele\acr-10, Cele\acr-11" "Xtro\chrnd, Xtro\chrna6, Xtro\chrna3, Xtro\chrne, Xtro\chrna1.2, Xtro\chrna7, Xtro\chrna5, Xtro\chrna2, Xtro\chrng, Xtro\chrnb3, Xtro\chrna9, Xtro\chrna1, Xtro\chrnb2" "Mmus\Chrnb2, Mmus\Chrna10, Mmus\Htr3b, Mmus\Chrnb3, Mmus\Chrna4, Mmus\Chrnd, Mmus\Chrna6, Mmus\Chrna3, Mmus\Htr3a, Mmus\Chrna5, Mmus\Chrng, Mmus\Chrne, Mmus\Chrna7, Mmus\Chrna2, Mmus\Chrna9, Mmus\Chrnb4, Mmus\Chrna1, Mmus\Chrnb1" "Hsap\HTR3E, Hsap\CHRNA3, Hsap\CHRNG, Hsap\CHRNB1, Hsap\CHRNB3, Hsap\CHRNA2, Hsap\CHRNA10, Hsap\CHRNA5, Hsap\CHRNB2, Hsap\CHRNB4, Hsap\HTR3A, Hsap\CHRNA1, Hsap\HTR3D, Hsap\CHRNA9, Hsap\CHRNA7, Hsap\HTR3C, Hsap\CHRND, Hsap\CHRFAM7A, Hsap\HTR3B, Hsap\CHRNA4, Hsap\CHRNA6, Hsap\CHRNE" FBgn0065737 l(2)SH0540 lethal (2) SH0540 http://flybase.org/reports/FBgn0065737 gene - - - "l(2)SH0540, l(2)SH2 0540" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052111 CR32111 - http://flybase.org/reports/FBgn0052111 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32111, CR32111" - CR32111 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002583 Rp7-8 Ribosomal protein 7/8 http://flybase.org/reports/FBgn0002583 - gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity translation ; GO:0006412 | inferred from sequence or structural similarity ribosome ; GO:0005840 | inferred from sequence or structural similarity "Rp7/8, M(1)5D6A, Rp7-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052851 CG32851 - http://flybase.org/reports/FBgn0052851 protein_coding_gene - - - CG32851 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266852 CR45313 - http://flybase.org/reports/FBgn0266852 non_protein_coding_gene - - - CR45313 - CR45313 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001683 l(1)ESHS4 lethal (1) ESHS4 http://flybase.org/reports/FBgn0001683 - gene - - - l(1)ESHS4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030326 CG2444 - http://flybase.org/reports/FBgn0030326 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model "BcDNA:LP01642, CG2444, DIGF-6" IPR029277:Single domain Von Willebrand factor type C domain CG2444 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004477 l(1)air1 lethal aberrant immune response 1 http://flybase.org/reports/FBgn0004477 - gene - - - "air1, l(1)air[1], l(1)air1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,embryonic/larval hindgut,embryonic/larval lymph gland,melanotic mass" FBgn0267704 flam flamenco http://flybase.org/reports/FBgn0267704 non_protein_coding_gene - male courtship behavior ; GO:0008049 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype - "flam, CR46037, lincRNA.1041, flamenco, COM, COM/flam" - CR46037 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266799 CR45261 - http://flybase.org/reports/FBgn0266799 non_protein_coding_gene - - - CR45261 - CR45261 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024210 miscue miscue http://flybase.org/reports/FBgn0024210 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available miscue - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085285 CG34256 - http://flybase.org/reports/FBgn0085285 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34256 IPR012674:Calycin CG34256 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041616 SM3-6 SM3-6 http://flybase.org/reports/FBgn0041616 gene - - - SM3-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069235 gl(2L)137-8 gl(2L)137-8 http://flybase.org/reports/FBgn0069235 gene molecular_function ; GO:0003674 | no biological data available anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)137-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,non-rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryo,germline clone,maternal effect,posterior" FBgn0039986 CG18257 - http://flybase.org/reports/FBgn0039986 protein_coding_gene - - - CG18257 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264301 CG43779 - http://flybase.org/reports/FBgn0264301 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43779, CG15639" - CG43779 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263352 Unr Upstream of N-ras http://flybase.org/reports/FBgn0263352 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002059 mRNA 3'-UTR binding ; GO:0003730 | inferred from physical interaction with msl-2 protein binding ; GO:0005515 | inferred from physical interaction with Sxl "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002059 dosage compensation complex assembly ; GO:0042714 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype dosage compensation ; GO:0007549 | inferred from direct assay negative regulation of translation ; GO:0017148 | inferred from direct assay dosage compensation by hyperactivation of X chromosome ; GO:0009047 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay "Unr, UNR, BcDNA:LD13080, CR32028, MRE30, CG7015, dUNR, unr" "IPR002059:Cold-shock protein, DNA-binding, IPR011129:Cold shock domain, IPR019844:Cold-shock conserved site, IPR012340:Nucleic acid-binding, OB-fold, IPR015943:WD40/YVTN repeat-like-containing domain" CG7015 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-121d4.3, Drer\csde1" - - Xtro\csde1 Mmus\Csde1 Hsap\CSDE1 FBgn0037584 CG7963 - http://flybase.org/reports/FBgn0037584 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG7963 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7963 11-Aug-17 DroID_v2017_08 "Drer\LOC100535458, Drer\LOC100148466, Drer\LOC103910994, Drer\zgc:113090, Drer\LOC101885678, Drer\zgc:174275, Drer\LOC101883594, Drer\zgc:113372, Drer\zgc:174623, Drer\LOC100332847, Drer\zgc:163077, Drer\si:ch1073-224n8.1, Drer\LOC560148, Drer\LOC100536348, Drer\si:dkey-201g16.1" Scer\ZAP1 "Cele\eor-1, Cele\M03D4.4, Cele\klf-3, Cele\klf-1, Cele\lsy-2" Xtro\hic1 Mmus\Gm14322 - viable FBgn0263478 snoRNA:Edc3-a - http://flybase.org/reports/FBgn0263478 snoRNA_gene - - - snoRNA:Edc3-a - CR43593 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085417 natalisin natalisin http://flybase.org/reports/FBgn0085417 protein_coding_gene - male mating behavior ; GO:0060179 | inferred from mutant phenotype - "CG34388, CG14842, CG14843, natalisin, NTL, ntl, Ntl" IPR011989:Armadillo-like helical CG34388 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,courtship behavior defective,male,grooming behavior defective,female,mating behavior defective" FBgn0262361 CG43059 - http://flybase.org/reports/FBgn0262361 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43059 - CG43059 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082938 snoRNA:Me28S-C2645a - http://flybase.org/reports/FBgn0082938 snoRNA_gene - - - "CR34587, snoRNA:Me28S-C2645a, Me28S-C2645a(DmSnR64), snoRNA:Me28S-Cm2645a, Me28S-Cm2645a, DmSnR64, DmSnR64a, SnR64, Me28S-C2645a" - CR34587 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001053 fs(3)K1 female sterile (3) K1 http://flybase.org/reports/FBgn0001053 - gene - - - fs(3)K1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "dorsal appendage,maternal effect" FBgn0260087 2L4333 - http://flybase.org/reports/FBgn0260087 gene - - - 2L4333 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0069961 CG41051 - http://flybase.org/reports/FBgn0069961 protein_coding_gene - - - CG41051 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013650 ms(2)ry6 ms(2)ry6 http://flybase.org/reports/FBgn0013650 - gene - - - "ms(2)6, ms(2)ry6" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0011086 l(1)Q44 lethal (1) Q44 http://flybase.org/reports/FBgn0011086 FBgn0010210 gene - - - l(1)Q44 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030108 Gr8a Gustatory receptor 8a http://flybase.org/reports/FBgn0030108 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 chemosensory behavior ; GO:0007635 | inferred from mutant phenotype response to insecticide ; GO:0017085 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement sensory perception of taste ; GO:0050909 | non-traceable author statement response to L-canavanine ; GO:1901354 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr8D1, CG15371, Gr8a, GR8a" IPR013604:7TM chemoreceptor CG15371 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,chemosensitive behavior defective,neurophysiology defective" "S-type sensilla S3,S-type sensilla S5,S-type sensilla S10" FBgn0262944 CR43263 - http://flybase.org/reports/FBgn0262944 non_protein_coding_gene - - - CR43263 - CR43263 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026677 l(1)G0105 lethal (1) G0105 http://flybase.org/reports/FBgn0026677 - gene - - - l(1)G0105 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033222 CG12824 - http://flybase.org/reports/FBgn0033222 protein_coding_gene - - - CG12824 - CG12824 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266869 CR45330 - http://flybase.org/reports/FBgn0266869 non_protein_coding_gene - - - CR45330 - CR45330 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263092 CR43360 - http://flybase.org/reports/FBgn0263092 pseudogene_attribute - - - CR43360 - CR43360 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027955 l(3)j6E3 lethal (3) j6E3 http://flybase.org/reports/FBgn0027955 gene - - - l(3)j6E3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036139 CG6216 - http://flybase.org/reports/FBgn0036139 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6216 - CG6216 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011617 l(1)I33g20 lethal (1) I33g20 http://flybase.org/reports/FBgn0011617 FBgn0010206 gene - - - "l(1)33g20, l(1)I33g20" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0086062 snoRNA:Me28S-C788b - http://flybase.org/reports/FBgn0086062 snoRNA_gene - - - "snoRNA:Me28S-C788b, Me28S-Cm788b, CR34691, DmSnR58b" - CR34691 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005240 l(3)R78 lethal of Roberts 78 http://flybase.org/reports/FBgn0005240 - gene - - - "l(3)B78, l(3)R78" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0045047 fs(1)261EL female sterile (1) 261EL http://flybase.org/reports/FBgn0045047 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)261EL - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile ovary FBgn0028104 l(3)S071710 lethal (3) S071710 http://flybase.org/reports/FBgn0028104 gene - - - "0717/10, l(3)S071710" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0032017 CG7810 - http://flybase.org/reports/FBgn0032017 protein_coding_gene - - U2 snRNP ; GO:0005686 | colocalizes_with inferred from direct assay CG7810 "IPR018613:Protein of unknown function DUF2052, coiled-coil" CG7810 11-Aug-17 DroID_v2017_08 Drer\ccdc97 - Cele\R10D12.13 Xtro\ccdc97 Mmus\Ccdc97 Hsap\CCDC97 viable FBgn0037760 FBXO11 F-box protein 11 http://flybase.org/reports/FBgn0037760 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003126 ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model protein ubiquitination ; GO:0016567 | inferred from electronic annotation with InterPro:IPR029799 regulation of gene silencing by RNA ; GO:0060966 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model siRNA loading onto RISC involved in chromatin silencing by small RNA ; GO:0070923 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern ubiquitin ligase complex ; GO:0000151 | inferred from electronic annotation with InterPro:IPR029799 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model cytoplasm ; GO:0005737 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "Fbxo11, dFBX011, CG9461, FBX011, FBXO11, UBR6" "IPR007742:Periplasmic copper-binding protein NosD, beta helix domain, IPR001810:F-box domain, IPR003126:Zinc finger, UBR-type, IPR006626:Parallel beta-helix repeat, IPR006633:Carbohydrate-binding/sugar hydrolysis domain, IPR011050:Pectin lyase fold/virulence factor, IPR029799:F-box only protein 11, IPR022441:Parallel beta-helix repeat-2, IPR012334:Pectin lyase fold" CG9461 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-245p14.2, Drer\fbxo11a, Drer\fbxo11b" - "Cele\dre-1, Cele\BE0003N10.3" "Xtro\fbxo11, Xtro\fbxo10" "Mmus\Fbxo11, Mmus\Fbxo10" "Hsap\FBXO11, Hsap\FBXO10" "viable,fertile" FBgn0011262 EnNuc-m Endonuclease mitochondrial http://flybase.org/reports/FBgn0011262 - gene endodeoxyribonuclease activity ; GO:0004520 | inferred from direct assay "DNA catabolic process, endonucleolytic ; GO:0000737 | inferred from direct assay" mitochondrion ; GO:0005739 | inferred from direct assay EnNuc-m - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031317 Charon Charon http://flybase.org/reports/FBgn0031317 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay NF-kappaB binding ; GO:0051059 | inferred from direct assay negative regulation of NF-kappaB transcription factor activity ; GO:0032088 | inferred from mutant phenotype positive regulation of NF-kappaB import into nucleus ; GO:0042346 | inferred from mutant phenotype regulation of defense response to bacterium ; GO:1900424 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype regulation of innate immune response ; GO:0045088 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype positive regulation of NF-kappaB transcription factor activity ; GO:0051092 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "anon-WO0140519.11, CG5118, pickle, Charon" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG5118 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0044409 Scim18 Sensitized chromosome inheritance modifier 18 http://flybase.org/reports/FBgn0044409 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0022749 anon-E1 anon-E1 http://flybase.org/reports/FBgn0022749 - gene - - - "E1, anon-E1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040299 Myo28B1 Myosin 28B1 http://flybase.org/reports/FBgn0040299 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609 motor activity ; GO:0003774 | inferred from sequence or structural similarity with NCBI_gi:613788 actin-dependent ATPase activity ; GO:0030898 | inferred from direct assay microfilament motor activity ; GO:0000146 | inferred by curator from GO:0016459,GO:0030898 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from sequence or structural similarity with NCBI_gi:613788" "actin filament-based movement ; GO:0030048 | inferred by curator from GO:0016459,GO:0030898" myosin complex ; GO:0016459 | inferred from direct assay myosin complex ; GO:0016459 | inferred from sequence or structural similarity "Myo28B, 28B, VIIb 28B, DmVIIB, CG6976, Myo28B1, myo 28B1, myo28B, Myo18" "IPR000048:IQ motif, EF-hand binding site, IPR000299:FERM domain, IPR000857:MyTH4 domain, IPR001609:Myosin head, motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR018979:FERM, N-terminal, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR029071:Ubiquitin-related domain, IPR011993:PH domain-like" CG6976 11-Aug-17 DroID_v2017_08 "Drer\myo9ab, Drer\myo15ab, Drer\myo7ab, Drer\myo9aa, Drer\myo7aa, Drer\LOC556989, Drer\myo15aa, Drer\myo7bb, Drer\si:ch73-194h10.2, Drer\myo3b, Drer\myo10l1, Drer\myo10l3, Drer\myo10, Drer\myo9b, Drer\myo15b" "Scer\MYO2, Scer\MYO1" Cele\hum-6 "Xtro\myo7a, Xtro\myo3b, Xtro\myo10.2, Xtro\myo3a, Xtro\myo10, Xtro\myo9a" "Mmus\Myo7b, Mmus\Myo3a, Mmus\Myo7a, Mmus\Myo3b, Mmus\Myo9b, Mmus\Myo9a, Mmus\Myo15, Mmus\Myo10" "Hsap\MYO9B, Hsap\MYO7A, Hsap\MYO9A, Hsap\MYO15A, Hsap\MYO3A, Hsap\MYO7B, Hsap\MYO3B, Hsap\MYO10" "viable,visible" "trichogen cell,male genitalia" FBgn0004542 l(4)102CDm lethal (4) 102CDm http://flybase.org/reports/FBgn0004542 - gene - - - "l(4)CDm, l(4)27, l(4)102CDm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0037519 CG3014 - http://flybase.org/reports/FBgn0037519 protein_coding_gene - - - CG3014 "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG3014 11-Aug-17 DroID_v2017_08 "Drer\arrdc1a, Drer\si:ch211-130m23.2, Drer\LOC799768, Drer\arrdc3a, Drer\txnipb, Drer\txnipa, Drer\arrdc3b, Drer\arrdc2, Drer\zgc:110626, Drer\zgc:110353, Drer\arrdc1b" "Scer\ECM21, Scer\RIM8, Scer\ALY2, Scer\ART5, Scer\ALY1, Scer\CSR2, Scer\ROD1, Scer\ROG3, Scer\LDB19" "Cele\arrd-5, Cele\arrd-25, Cele\arrd-16, Cele\rnh-1.2, Cele\arrd-27, Cele\arrd-19, Cele\arrd-18, Cele\arrd-7, Cele\arrd-22, Cele\arrd-23, Cele\arrd-3, Cele\arrd-2, Cele\arrd-14, Cele\arrd-4, Cele\arrd-1, Cele\arrd-6, Cele\arrd-15, Cele\arrd-24, Cele\arrd-9, Cele\arrd-12, Cele\arrd-8, Cele\arrd-11, Cele\arrd-13" "Xtro\arrdc4, Xtro\arrdc2, Xtro\arrdc3, Xtro\txnip" "Mmus\Arrdc2, Mmus\Arrdc1, Mmus\Arrdc4, Mmus\Arrdc5, Mmus\Arrdc3, Mmus\Txnip" "Hsap\ARRDC3, Hsap\TXNIP, Hsap\ARRDC1, Hsap\ARRDC4, Hsap\ARRDC2, Hsap\ARRDC5" FBgn0060651 l(3)S083407b lethal (3) S083407b http://flybase.org/reports/FBgn0060651 gene - - - "l(3)S083407, 0834/07, l(3)S083407b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053394 5SrRNA:CR33394 5SrRNA:CR33394 http://flybase.org/reports/FBgn0053394 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33394, 5SrRNA:CR33394" - CR33394 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002853 Msp Muscle-specific protein http://flybase.org/reports/FBgn0002853 - gene - - - Msp - - 11-Aug-17 DroID_v2017_08 - - - - - - ventral oblique muscle FBgn0041241 Gr47b Gustatory receptor 47b http://flybase.org/reports/FBgn0041241 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "CG30030, Gr47F1, 47F.1, GR47F.1, Gr47b, GR47b" - CG30030 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0069422 JJF064 JJF064 http://flybase.org/reports/FBgn0069422 gene - - - JJF064 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0266803 CR45265 - http://flybase.org/reports/FBgn0266803 non_protein_coding_gene - - - CR45265 - CR45265 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259944 Ttd9 TRPL translocation defect 9 http://flybase.org/reports/FBgn0259944 protein_coding_gene - - - Ttd9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051717 CG31717 - http://flybase.org/reports/FBgn0051717 protein_coding_gene - - - "Css2, BcDNA:AT30094, CG31717" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG31717 11-Aug-17 DroID_v2017_08 "Drer\plpp7, Drer\plpp6" - Cele\T13C5.6 "Xtro\plpp6, Xtro\plpp7" "Mmus\Plpp6, Mmus\Plpp7" "Hsap\PLPP7, Hsap\PLPP6" "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0260295 GSd417 - http://flybase.org/reports/FBgn0260295 gene - - - GSd417 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004998 cr-c cream c http://flybase.org/reports/FBgn0004998 - gene - - - cr-c - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0025488 l(3)82EFc lethal (3) 82EFc http://flybase.org/reports/FBgn0025488 - gene - - - l(3)82EFc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0001266 Indented Indented http://flybase.org/reports/FBgn0001266 - gene - - - "Ind, Indented" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive" "eye,heat sensitive" FBgn0036862 Gbs-76A Glycogen binding subunit 76A http://flybase.org/reports/FBgn0036862 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B - - "149039_at, CG9619, Gbs-76A, GBS-76A" "IPR005036:CBM21 (carbohydrate binding type-21) domain, IPR013783:Immunoglobulin-like fold" CG9619 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-167b20.8, Drer\ppp1r3b, Drer\zgc:77112, Drer\ppp1r3cb, Drer\si:ch211-152c8.5, Drer\ppp1r3ca, Drer\ppp1r3ab, Drer\ppp1r3aa, Drer\ppp1r3db, Drer\ppp1r3da" "Scer\PIG1, Scer\GIP2, Scer\PIG2, Scer\GAC1" "Cele\H18N23.2, Cele\CC8.2" "Xtro\ppp1r3c.2, Xtro\ppp1r3b, Xtro\ppp1r3c.1, Xtro\ppp1r3d" "Mmus\Ppp1r3d, Mmus\Ppp1r3c, Mmus\Ppp1r3g, Mmus\Ppp1r3a, Mmus\Ppp1r3b, Mmus\Ppp1r3f, Mmus\Ppp1r3e" "Hsap\PPP1R3E, Hsap\PPP1R3F, Hsap\PPP1R3C, Hsap\PPP1R3A, Hsap\PPP1R3G, Hsap\PPP1R3D, Hsap\PPP1R3B" "viable,fertile" FBgn0034529 FAM21 Family with sequence similarity 21 http://flybase.org/reports/FBgn0034529 protein_coding_gene - - WASH complex ; GO:0071203 | inferred from direct assay "FAM21, CG16742, fam21" - CG16742 11-Aug-17 DroID_v2017_08 "Drer\fam21c, Drer\dub, Drer\zgc:153184" - Cele\H39E23.3 Xtro\fam21a "Mmus\Rcsd1, Mmus\Fam21" "Hsap\RCSD1, Hsap\WASHC2A, Hsap\WASHC2C" viable FBgn0001939 l(2)25Fe lethal (2) 25Fe http://flybase.org/reports/FBgn0001939 - gene - - - "l(2)gdh-3, l(2)25Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030955 CG6891 - http://flybase.org/reports/FBgn0030955 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR002108 - intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR002108 CG6891 "IPR002108:Actin-depolymerising factor homology domain, IPR029006:ADF-H/Gelsolin-like domain" CG6891 11-Aug-17 DroID_v2017_08 Drer\cotl1 - - Xtro\cotl1 Mmus\Cotl1 Hsap\COTL1 viable FBgn0003868 tt tilt http://flybase.org/reports/FBgn0003868 - gene - - - tt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" "wing,wing vein L3,pigment cell" FBgn0013227 E(var)125 E(var)125 http://flybase.org/reports/FBgn0013227 - gene - - - E(var)125 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0031111 Obp19c Odorant-binding protein 19c http://flybase.org/reports/FBgn0031111 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "19c, CG15457, Obp19c, DmelObp19c" IPR006170:Pheromone/general odorant binding protein CG15457 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0058288 CG40288 - http://flybase.org/reports/FBgn0058288 protein_coding_gene - - - CG40288 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083029 snoRNA:Psi18S-525j snoRNA:Psi18S-525j http://flybase.org/reports/FBgn0083029 snoRNA_gene - - - "snoRNA:Psi18S-525j, psi18S-525j, CR34586" - CR34586 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005201 l(3)AM1 lethal (3) AM1 http://flybase.org/reports/FBgn0005201 - gene - - - l(3)AM1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,partially" FBgn0082628 S(CycE[JP])20S1 S(CycE[JP])20S1 http://flybase.org/reports/FBgn0082628 gene - - - "20S1, S(CycE[JP])20S1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026566 CG1307 - http://flybase.org/reports/FBgn0026566 - protein_coding_gene aminoacyl-tRNA hydrolase activity ; GO:0004045 | inferred from electronic annotation with InterPro:IPR002833 - mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9Y3E5 "BG:DS00004.12, CG1307" "IPR002833:Peptidyl-tRNA hydrolase, PTH2, IPR023476:Peptidyl-tRNA hydrolase II domain" CG1307 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-19e4.5, Drer\ptrh2" Scer\PTH2 Cele\C24G6.8 Xtro\ptrh2 Mmus\Ptrh2 Hsap\PTRH2 FBgn0026570 CG5704 - http://flybase.org/reports/FBgn0026570 FBgn0035310 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "LD30049, BEST:LD30049, CG5704" "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG5704 11-Aug-17 DroID_v2017_08 Drer\serhl Scer\YNR064C Cele\W01A11.1 "Xtro\serhl2, Xtro\serhl" Mmus\Serhl Hsap\SERHL2 viable FBgn0051515 CG31515 - http://flybase.org/reports/FBgn0051515 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG31515 "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG31515 11-Aug-17 DroID_v2017_08 - - "Cele\tag-290, Cele\C34F6.1, Cele\mec-1" - Mmus\Spint3 - DRSC13610 IE 3.641029502 3.459508277 4.668911547 4.633936408 -0.668408913 1.097790976 FBgn0060844 l(3)S049205 lethal (3) S049205 http://flybase.org/reports/FBgn0060844 gene - - - "0492/05, l(3)S049205" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024547 l(3)L3659 lethal (3) L3659 http://flybase.org/reports/FBgn0024547 - gene - - - "1(3)L3659, l(3)L3659" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004151 l(2)57Ae lethal (2) 57Ae http://flybase.org/reports/FBgn0004151 - gene - - - l(2)57Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052510 CG32510 - http://flybase.org/reports/FBgn0052510 protein_coding_gene - - - CG32510 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262070 EG149 - http://flybase.org/reports/FBgn0262070 gene - - - EG149 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000631 fai faint http://flybase.org/reports/FBgn0000631 - gene - - - fai - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval cuticle,cephalopharyngeal skeleton" FBgn0034782 CG12490 - http://flybase.org/reports/FBgn0034782 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 CG12490 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG12490 11-Aug-17 DroID_v2017_08 "Drer\slc17a8, Drer\ppt1, Drer\slc17a5, Drer\slc17a7a, Drer\slc17a9a, Drer\si:ch1073-513e17.1, Drer\slc17a6b, Drer\slc17a6a" "Scer\TNA1, Scer\YIL166C, Scer\THI73, Scer\DAL5" "Cele\T27D12.1, Cele\Y51B9A.6, Cele\K08C7.1, Cele\vglu-3, Cele\M117.1, Cele\W04C9.6, Cele\T19D12.9, Cele\F56A4.10, Cele\slc-17.4, Cele\F41C3.2, Cele\C18H9.5, Cele\T22F3.10, Cele\slc-17.9, Cele\slc-17.2, Cele\eat-4, Cele\Y4C6B.4, Cele\Y19D10A.11, Cele\R10D12.1, Cele\Y4C6B.3, Cele\T22F3.11, Cele\T22F3.7, Cele\C01B4.7, Cele\F59A1.13, Cele\Y19D10A.5, Cele\C01B4.8, Cele\slc-17.5, Cele\slc-17.3, Cele\Y15E3A.4, Cele\C39E9.7, Cele\T22F3.8, Cele\C35A5.3, Cele\K11G9.5, Cele\F10C2.7, Cele\T19D12.10, Cele\M162.5, Cele\D1046.4, Cele\Y19D10A.8, Cele\F56A4.12, Cele\vglu-2, Cele\Y19D10A.4, Cele\slc-17.8, Cele\F44E7.7, Cele\H11E01.2, Cele\C18D1.2, Cele\F11A5.9, Cele\slc-17.1, Cele\T02B11.6, Cele\cima-1, Cele\T01H3.3, Cele\T28H11.8" Xtro\slc17a7 "Mmus\Slc17a5, Mmus\Slc17a4, Mmus\Slc17a3, Mmus\Slc17a6, Mmus\Slc17a1, Mmus\Slc17a8, Mmus\Slc17a2, Mmus\Slc17a7" "Hsap\SLC17A6, Hsap\SLC17A2, Hsap\SLC17A3, Hsap\SLC17A5, Hsap\SLC17A7, Hsap\SLC17A1, Hsap\SLC17A8, Hsap\SLC17A4" "partially lethal - majority die,some die during pupal stage" FBgn0283455 EC2-12 Enhancer of CCT 2-12 http://flybase.org/reports/FBgn0283455 gene - - - EC2-12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039443 TwdlS TweedleS http://flybase.org/reports/FBgn0039443 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlS, CG14242" IPR004145:Domain of unknown function DUF243 CG14242 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267235 CR45675 - http://flybase.org/reports/FBgn0267235 non_protein_coding_gene - - - "CR45675, lincRNA.426" - CR45675 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265344 CR44298 - http://flybase.org/reports/FBgn0265344 non_protein_coding_gene - - - CR44298 - CR44298 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060942 l(3)S039605c lethal (3) S039605c http://flybase.org/reports/FBgn0060942 gene - - - "0396/05, l(3)S039605c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0065795 l(2)SH0417 lethal (2) SH0417 http://flybase.org/reports/FBgn0065795 gene - - - "l(2)SH0417, l(2)SH2 0417" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022728 l(3)GPMG-30 lethal (3) GPMG-30 http://flybase.org/reports/FBgn0022728 - gene - - - "GPMG-30, l(3)GPMG-30" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259250 EP-489 - http://flybase.org/reports/FBgn0259250 gene - - - EP-489 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0028891 CG18482 - http://flybase.org/reports/FBgn0028891 protein_coding_gene - - - "DS03023.4, BG:DS03023.4, CG18482" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC01931 IK 0.054826439 -2.234369904 0.732995415 -0.420752721 -0.366047108 2.132660175 FBgn0044512 l(3)S007708 lethal (3) S007708 http://flybase.org/reports/FBgn0044512 gene - - - "0077/08, l(3)S007708" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001651 l(1)ds3 lethal (1) discs small 3 http://flybase.org/reports/FBgn0001651 - gene - - - "l(1)d.sml.-3, l(1)ds3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0261616 CG42705 - http://flybase.org/reports/FBgn0261616 protein_coding_gene - - - "CG42705, CG47205" - CG42705 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036018 CG3335 - http://flybase.org/reports/FBgn0036018 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity helicase activity ; GO:0004386 | inferred from sequence or structural similarity - - "Dm-RBD-1, Q9VT19, cg3335, CG3335" "IPR000504:RNA recognition motif domain, IPR034423:Probable RNA-binding protein 19, RNA recognition motif 5, IPR034421:Probable RNA-binding protein 19, RNA recognition motif 6, IPR034420:Probable RNA-binding protein 19, RNA recognition motif 4, IPR034419:Probable RNA-binding protein 19, RNA recognition motif 3, IPR034418:Probable RNA-binding protein 19, RNA recognition motif 1" CG3335 11-Aug-17 DroID_v2017_08 Drer\rbm19 Scer\MRD1 Cele\rbd-1 Xtro\rbm19 Mmus\Rbm19 Hsap\RBM19 FBgn0263777 CG43694 - http://flybase.org/reports/FBgn0263777 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43694 - CG43694 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067886 Mod(Prat:bw)1-1 Mod(Prat:bw)1-1 http://flybase.org/reports/FBgn0067886 gene - - - "Mod-1-1, Mod(Prat:bw)1-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052289 tRNA:Cys-GCA-1-2 transfer RNA:Cysteine-GCA 1-2 http://flybase.org/reports/FBgn0052289 tRNA_gene UGC codon-amino acid adaptor activity ; GO:0033414 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033414 cytosol ; GO:0005829 | inferred by curator from GO:0033414 "CR32289, AE002584.trna15-CysGCA, tRNA:C:GCA:AE002584-d, chr3L.trna15-CysGCA, tRNA:Cys-GCA-1-2, tRNA:CR32289, tRNA-Cys-GCA-1-2, UGC" - CR32289 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003570 Su(par) Suppressor of paralog http://flybase.org/reports/FBgn0003570 - gene - - - Su(par) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034050 bug bunker gear http://flybase.org/reports/FBgn0034050 protein_coding_gene - detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype - "CG8297, bug" IPR012336:Thioredoxin-like fold CG8297 11-Aug-17 DroID_v2017_08 Drer\txndc15 - Cele\C53D6.4 Xtro\txndc15 Mmus\Txndc15 Hsap\TXNDC15 viable FBgn0028130 l(3)S051311 lethal (3) S051311 http://flybase.org/reports/FBgn0028130 gene - - - "0513/11, l(3)S051311" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050192 CG30192 - http://flybase.org/reports/FBgn0050192 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT30929, CG30192" - CG30192 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267124 CR45564 - http://flybase.org/reports/FBgn0267124 non_protein_coding_gene - - - "lincRNA.916, CR45564" - CR45564 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022273 l(2)k00213 lethal (2) k00213 http://flybase.org/reports/FBgn0022273 - gene - - - l(2)k00213 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039373 CG5024 - http://flybase.org/reports/FBgn0039373 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "BcDNA:AT16150, CG5024, gene1, MLC1" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG5024 11-Aug-17 DroID_v2017_08 "Drer\calb2a, Drer\cabp4, Drer\tnnc1b, Drer\cabp2b, Drer\calb2b, Drer\efcab6, Drer\cabp5b, Drer\calm3a, Drer\si:ch211-197n1.2, Drer\calm2b, Drer\calml4b, Drer\pvalb3, Drer\rhbdl3, Drer\cabp7b, Drer\pvalb9, Drer\efcab2, Drer\pvalb6, Drer\calm2a, Drer\pvalb2, Drer\efcab11, Drer\pvalb8, Drer\pvalb1, Drer\cabp2a, Drer\caln1, Drer\tnnc2, Drer\pvalb4, Drer\caln2, Drer\cabp1a, Drer\tnnc1a, Drer\calb1, Drer\calm1b, Drer\cabp5a, Drer\calml4a, Drer\cabp1b, Drer\calm1a, Drer\calm3b, Drer\scgn" "Scer\MLC2, Scer\MLC1, Scer\CMD1" "Cele\cal-4, Cele\cmd-1, Cele\cal-2, Cele\cal-3, Cele\cal-1" "Xtro\scgn, Xtro\tnnc2, Xtro\ocm, Xtro\ocm.2, Xtro\cabp7, Xtro\pgm1, Xtro\pvalb.2, Xtro\pvalb.1, Xtro\tnnc1, Xtro\calm2, Xtro\LOC548651, Xtro\efcab6, Xtro\pvalb, Xtro\cabp4, Xtro\calml4, Xtro\calm1, Xtro\calb1" "Mmus\Cabp7, Mmus\Efcab7, Mmus\Cabp2, Mmus\Pvalb, Mmus\Calm5, Mmus\Efcab2, Mmus\Cabp1, Mmus\Tnnc1, Mmus\Calml4, Mmus\Calb2, Mmus\Calm4, Mmus\Caln1, Mmus\Cabp5, Mmus\Efcab3, Mmus\Calm1, Mmus\Tnnc2, Mmus\Efcab11, Mmus\Cabp4, Mmus\Calb1, Mmus\Calml3, Mmus\Scgn, Mmus\Calm2, Mmus\Efcab9, Mmus\Ocm, Mmus\1700023F06Rik, Mmus\Spata21, Mmus\Calm3, Mmus\Rhbdl3, Mmus\Efcab6" "Hsap\PVALB, Hsap\CALML3, Hsap\EFCAB6, Hsap\EFCAB9, Hsap\CALML5, Hsap\EFCAB11, Hsap\CALB1, Hsap\CALB2, Hsap\CABP4, Hsap\CABP1, Hsap\EFCAB13, Hsap\CALML4, Hsap\OCM, Hsap\CALML6, Hsap\SCGN, Hsap\TNNC2, Hsap\EFCAB7, Hsap\TNNC1, Hsap\CABP7, Hsap\CALM2, Hsap\CALN1, Hsap\CABP5, Hsap\OCM2, Hsap\CABP2, Hsap\CALM1, Hsap\EFCAB3, Hsap\CALM3, Hsap\SPATA21, Hsap\RHBDL3, Hsap\EFCAB2" viable FBgn0085230 CG34201 - http://flybase.org/reports/FBgn0085230 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34201 - CG34201 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038957 CG7059 - http://flybase.org/reports/FBgn0038957 protein_coding_gene "2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity ; GO:0046538 | inferred from biological aspect of ancestor with PANTHER:PTN000231842" gluconeogenesis ; GO:0006094 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 regulation of pentose-phosphate shunt ; GO:0043456 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 CG7059 "IPR001345:Phosphoglycerate/bisphosphoglycerate mutase, active site, IPR005952:Phosphoglycerate mutase 1, IPR013078:Histidine phosphatase superfamily, clade-1, IPR029033:Histidine phosphatase superfamily" CG7059 11-Aug-17 DroID_v2017_08 "Drer\pgam1a, Drer\bpgm, Drer\pgam2, Drer\pgam1b, Drer\tigara" "Scer\GPM3, Scer\YOR283W, Scer\GPM1, Scer\GPM2" - "Xtro\pgam2, Xtro\pgam1, Xtro\bpgm" "Mmus\Bpgm, Mmus\Tigar, Mmus\Pgam1, Mmus\Pgam2" "Hsap\PGAM1, Hsap\PGAM2, Hsap\PGAM4, Hsap\BPGM, Hsap\TIGAR" "viable,fertile" DRSC16187 E -0.335509939 0.096334528 -1.626037336 -0.695894881 1.072807439 -0.133014348 FBgn0052468 CG32468 - http://flybase.org/reports/FBgn0052468 protein_coding_gene - - - CG32468 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0029866 CG3842 - http://flybase.org/reports/FBgn0029866 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - - "CG3842, lincRNA.959" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG3842 11-Aug-17 DroID_v2017_08 "Drer\dhrs13a.2, Drer\rdh14b, Drer\cbr1l, Drer\si:dkey-174n20.1, Drer\si:ch211-165b10.3, Drer\ascc1, Drer\rdh12, Drer\dhrs13l1, Drer\zgc:153441, Drer\si:ch211-107o10.3, Drer\flj13639, Drer\dhrs13a.1, Drer\si:dkey-94e7.2, Drer\rdh14a, Drer\cbr1, Drer\dhrs13a.3, Drer\si:dkey-73n8.3, Drer\dhrsx, Drer\dhrs12, Drer\si:dkey-23o4.6, Drer\zgc:64106, Drer\zgc:112332, Drer\rdh12l" "Scer\ERG27, Scer\ENV9, Scer\GPI11, Scer\YKL107W, Scer\YNL181W" "Cele\E04F6.15, Cele\C27D8.4, Cele\dhs-22, Cele\DC2.5" "Xtro\ascc1, Xtro\dhrs13, Xtro\dhrs12, Xtro\rdh11, Xtro\rdh13, Xtro\rdh14, Xtro\dhrsx" "Mmus\Dhrs13, Mmus\Rdh14, Mmus\Rdh12, Mmus\Hsd17b7, Mmus\Dhrsx, Mmus\1700003E16Rik, Mmus\Rdh13, Mmus\Rdh11, Mmus\Ascc1, Mmus\Cbr1, Mmus\Wwox, Mmus\Cbr3" "Hsap\C2orf81, Hsap\OSTC, Hsap\CBR3, Hsap\RDH12, Hsap\RDH14, Hsap\RDH13, Hsap\DHRS12, Hsap\DHRS13, Hsap\HSD17B7, Hsap\CBR1, Hsap\RDH11, Hsap\DHRSX" "viable,fertile" FBgn0040634 CG4186 - http://flybase.org/reports/FBgn0040634 protein_coding_gene - - - CG4186 IPR009069:Cysteine alpha-hairpin motif superfamily CG4186 11-Aug-17 DroID_v2017_08 Drer\chchd7 Scer\COX23 Cele\chch-3 Xtro\chchd7 Mmus\Chchd7 Hsap\CHCHD7 viable FBgn0259460 C919 - http://flybase.org/reports/FBgn0259460 gene - - - C919 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0002149 l(2)KE33 lethal (2) KE33 http://flybase.org/reports/FBgn0002149 - gene - - - l(2)KE33 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260450 CalpC Calpain C http://flybase.org/reports/FBgn0260450 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | NOT non-traceable author statement inferred from key residues proteolysis ; GO:0006508 | NOT non-traceable author statement inferred from key residues cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000021568 cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement "CG3692, CalpC" "IPR001300:Peptidase C2, calpain, catalytic domain, IPR011992:EF-hand domain pair, IPR033883:Calpain subdomain III, IPR002048:EF-hand domain, IPR022682:Peptidase C2, calpain, large subunit, domain III, IPR022683:Peptidase C2, calpain, domain III, IPR022684:Peptidase C2, calpain family" CG3692 11-Aug-17 DroID_v2017_08 "Drer\adgb, Drer\capn3b, Drer\capn10, Drer\capn15, Drer\capn1a, Drer\si:ch211-202f3.4, Drer\capn12, Drer\si:dkeyp-50d11.2, Drer\capn5b, Drer\capn2l, Drer\capn2b, Drer\capn5a, Drer\capn1b, Drer\si:dkey-19b23.13, Drer\capn9, Drer\capn3a, Drer\zgc:136872, Drer\zgc:92480, Drer\si:ch211-202f3.3, Drer\zgc:85932, Drer\zgc:162184, Drer\zgc:55262" Scer\RIM13 "Cele\clp-3, Cele\clp-4, Cele\clp-6, Cele\tra-3, Cele\clp-1, Cele\cal-4, Cele\clp-7" "Xtro\capn1, Xtro\LOC100497805, Xtro\LOC100494922, Xtro\capn2.2, Xtro\capn6, Xtro\capn8, Xtro\capn13, Xtro\capn9, Xtro\capn10, Xtro\capn3, Xtro\capn7, Xtro\capn15" "Mmus\Capn8, Mmus\Capn12, Mmus\Adgb, Mmus\Capn15, Mmus\Capn13, Mmus\Capn3, Mmus\Capn7, Mmus\Capn2, Mmus\Capn5, Mmus\Capn11, Mmus\Capn1, Mmus\Capn9, Mmus\Capn6, Mmus\Capn10" "Hsap\CAPN15, Hsap\CAPN3, Hsap\CAPN10, Hsap\CAPN5, Hsap\CAPN8, Hsap\CAPN13, Hsap\CAPN7, Hsap\CAPN11, Hsap\CAPN9, Hsap\CAPN6, Hsap\CAPN2, Hsap\CAPN1, Hsap\CAPN12, Hsap\ADGB, Hsap\CAPN14" " larval stage , oogenesis stage && embryonic stage--adult stage " " larval salivary gland

, organism

" viable FBgn0051560 CG31560 - http://flybase.org/reports/FBgn0051560 protein_coding_gene - - - "CG10314, CG31560" - CG31560 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031064 CG12531 - http://flybase.org/reports/FBgn0031064 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002293 CG12531 "IPR002293:Amino acid/polyamine transporter I, IPR029485:Cationic amino acid transporter, C-terminal" CG12531 11-Aug-17 DroID_v2017_08 "Drer\zgc:63694, Drer\slc7a3a, Drer\slc7a3b, Drer\slc7a9, Drer\slc7a1, Drer\slc7a14a, Drer\slc7a4, Drer\slc7a6, Drer\slc7a8a, Drer\slc7a5, Drer\zgc:175280, Drer\slc7a14b, Drer\slc7a2" "Scer\LYP1, Scer\HIP1, Scer\UGA4, Scer\ALP1, Scer\MMP1, Scer\DIP5, Scer\AGP3, Scer\GAP1, Scer\CAN1, Scer\AGP1, Scer\SSY1, Scer\TAT1, Scer\PUT4, Scer\GNP1, Scer\SAM3, Scer\BAP2, Scer\BAP3, Scer\TAT2, Scer\MUP1, Scer\AGP2" "Cele\aat-4, Cele\aat-2, Cele\C50D2.2, Cele\B0454.6, Cele\F23F1.6, Cele\aat-1, Cele\Y53F4B.12" "Xtro\slc7a8, Xtro\slc7a3, Xtro\slc7a6, Xtro\slc7a14, Xtro\slc7a2.2, Xtro\slc7a4, Xtro\slc7a2.1, Xtro\slc7a1, Xtro\slc7a5" "Mmus\AU018091, Mmus\Slc7a5, Mmus\Slc7a1, Mmus\Slc7a2, Mmus\Slc7a4, Mmus\Slc7a14, Mmus\Slc7a6, Mmus\Slc7a3, Mmus\Slc7a8, Mmus\Slc7a9, Mmus\Slc7a7" "Hsap\SLC7A14, Hsap\SLC7A7, Hsap\SLC7A1, Hsap\SLC7A5, Hsap\SLC7A2, Hsap\SLC7A6, Hsap\SLC7A3, Hsap\SLC7A8, Hsap\SLC7A4, Hsap\SLC7A9" viable FBgn0003540 sts streaked sterni http://flybase.org/reports/FBgn0003540 - gene - - - sts - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,poor,fertile,reduced,body color defective" sternite FBgn0034539 CG11159 - http://flybase.org/reports/FBgn0034539 protein_coding_gene - salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern - CG11159 "IPR001916:Glycoside hydrolase, family 22, IPR023346:Lysozyme-like domain, IPR019799:Glycoside hydrolase, family 22, conserved site" CG11159 11-Aug-17 DroID_v2017_08 "Drer\lyz, Drer\LOC100334363, Drer\LOC100536671" - - Xtro\MGC89221 "Mmus\Lalba, Mmus\Lyzl6, Mmus\1700016D06Rik, Mmus\Spaca7, Mmus\Spaca4, Mmus\Spaca1, Mmus\Spaca3, Mmus\Lyz1, Mmus\Lyzl1, Mmus\9530003J23Rik, Mmus\Lyz2, Mmus\Spaca5, Mmus\Lyzl4" "Hsap\LYZL4, Hsap\LYZL6, Hsap\SPACA4, Hsap\SPACA5B, Hsap\LYZL1, Hsap\SPACA5, Hsap\SPACA7, Hsap\SPACA3, Hsap\LALBA, Hsap\LYZ, Hsap\SPACA1, Hsap\LYZL2" FBgn0067669 p105 p105 http://flybase.org/reports/FBgn0067669 gene - - - p105 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051907 CG31907 - http://flybase.org/reports/FBgn0051907 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR027328 - - "NEST:bs25f07, NEST:bs29b10, NEST:bs06f02, CG31907" "IPR001715:Calponin homology domain, IPR027328:Microtubule-associated protein RP/EB" CG31907 11-Aug-17 DroID_v2017_08 "Drer\mapre3b, Drer\mapre1a, Drer\mapre2, Drer\mapre3a, Drer\mapre1b" "Scer\BIM1, Scer\IMH1" "Cele\ebp-3, Cele\ebp-1, Cele\ebp-2" Xtro\mapre1 "Mmus\Mapre3, Mmus\Mapre2, Mmus\Mapre1" "Hsap\MAPRE1, Hsap\MAPRE3, Hsap\MAPRE2" viable DRSC00967 IE 1.503585057 0.354032456 1.613227878 0.611293931 0.228689891 -0.44140417 FBgn0023132 Z66 Z66 http://flybase.org/reports/FBgn0023132 - gene - - - Z66 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052230 ND-MLRQ NADH dehydrogenase (ubiquinone) MLRQ subunit http://flybase.org/reports/FBgn0052230 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O00483 cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001023184 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O00483" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN001023184 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O00483 "BEST:GH04411, BcDNA:RE56733, NUML, ND-MLRQ, CG32230" IPR010530:NADH-ubiquinone reductase complex 1 MLRQ subunit CG32230 11-Aug-17 DroID_v2017_08 "Drer\zgc:153317, Drer\ndufa4l2, Drer\ndufa4l, Drer\ndufa4l2a, Drer\ndufa4" - - Xtro\ndufa4 "Mmus\Ndufa4l2, Mmus\AA467197, Mmus\Ndufa4" "Hsap\NDUFA4, Hsap\NDUFA4L2, Hsap\C15orf48" "viable,fertile" DRSC11913 E -1.014917992 -0.660773253 -2.029159282 -0.854329629 1.364449046 0.13089929 FBgn0083267 E(smoDN)418 Enhancer of smoDN 418 http://flybase.org/reports/FBgn0083267 gene - - - E(smoDN)418 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023003 l(4)K-2 lethal (4) K-2 http://flybase.org/reports/FBgn0023003 - gene - - - l(4)K-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025482 l(3)Ax7 lethal (3) Ax7 http://flybase.org/reports/FBgn0025482 - gene - - - "Ax7, l(3)Ax7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004155 l(2)51Db lethal (2) 51Db http://flybase.org/reports/FBgn0004155 - gene - - - l(2)51Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005098 fs(3)108-17 female sterile (3) 108-17 http://flybase.org/reports/FBgn0005098 - gene - - - fs(3)108-17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "dorsal appendage,endochorion" FBgn0085159 l(3)S009515 l(3)S009515 http://flybase.org/reports/FBgn0085159 gene - - - l(3)S009515 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083971 CG34135 - http://flybase.org/reports/FBgn0083971 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34135 - CG34135 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005243 l(3)R112 lethal of Roberts 112 http://flybase.org/reports/FBgn0005243 - gene - - - "l(3)112, l(3)R112" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0024672 l(2)k02113 lethal (2) k02113 http://flybase.org/reports/FBgn0024672 - gene - - - "21/13, l(2)k02113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083094 cia ciambella http://flybase.org/reports/FBgn0083094 gene - meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype - cia - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern,spindle & meiotic telophase I | male,contractile ring & meiotic telophase I | male,spindle & meiotic telophase II | male,contractile ring & meiotic telophase II | male" FBgn0270925 CG4836 - http://flybase.org/reports/FBgn0270925 protein_coding_gene - "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR013154" - "CG4836, DM_7300579, bs36e10.y1, bs15h04.y1, anon-WO0140519.33, anon-WO0140519.105, SODH-1, Srd" "IPR011032:GroES-like, IPR013154:Alcohol dehydrogenase, N-terminal, IPR016040:NAD(P)-binding domain" CG4836 11-Aug-17 DroID_v2017_08 Drer\c2h1orf27 "Scer\BDH2, Scer\YML131W, Scer\SOR1, Scer\XYL2, Scer\SOR2, Scer\BDH1" "Cele\R04B5.5, Cele\D2063.1, Cele\R04B5.6" Xtro\sord Mmus\Sord Hsap\SORD "partially lethal - majority die,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0004501 fs(1)gammaa6 female sterile (1) gammaa6 http://flybase.org/reports/FBgn0004501 - gene - - - fs(1)gammaa6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028365 l(1)G0011 lethal (1) G0011 http://flybase.org/reports/FBgn0028365 gene - - - l(1)G0011 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0053144 CG33144 - http://flybase.org/reports/FBgn0053144 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with ari-1 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with ari-1 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 "CG12339, CG7621, CG33144, AAF58756.2, lincRNA.281" "IPR001841:Zinc finger, RING-type, IPR002867:IBR domain, IPR017907:Zinc finger, RING-type, conserved site, IPR031127:E3 ubiquitin ligase RBR family" CG33144 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-278j3.3, Drer\arih2, Drer\ankib1a, Drer\arih1l, Drer\rnf19b, Drer\rnf144b, Drer\ankib1b, Drer\rnf19a, Drer\rnf217, Drer\shrprbck1r, Drer\arih1, Drer\rnf144aa, Drer\rbck1, Drer\rnf144ab" "Scer\HEL1, Scer\ITT1" - "Xtro\rnf144b, Xtro\arih2, Xtro\rnf19a, Xtro\rnf217, Xtro\rnf144a, Xtro\cul9" "Mmus\Rnf144a, Mmus\Rnf144b, Mmus\Cul9, Mmus\Ankib1, Mmus\Sharpin, Mmus\Rnf19a, Mmus\Arih1, Mmus\Rnf19b, Mmus\Cul7, Mmus\Arih2, Mmus\Rbck1, Mmus\Rnf217" "Hsap\RBCK1, Hsap\RNF144A, Hsap\CUL7, Hsap\RNF217, Hsap\RNF144B, Hsap\RNF19B, Hsap\CUL9, Hsap\RNF19A, Hsap\ARIH2, Hsap\ARIH1, Hsap\ANKIB1" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC07024 E 0.007413568 -0.576921436 3.38040597 0.770979179 -0.008975287 -0.21984095 FBgn0033574 Spn47C Serpin 47C http://flybase.org/reports/FBgn0033574 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "Spn47C, CG7722, spn47C" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG7722 11-Aug-17 DroID_v2017_08 "Drer\serpinf1, Drer\serpine1, Drer\serpini1, Drer\serpine3, Drer\serpinb1l3, Drer\serpinb1, Drer\serpina7, Drer\agt, Drer\serping1, Drer\si:ch1073-416d2.3, Drer\serpinb1l2, Drer\zgc:174259, Drer\serpind1, Drer\serpina1l, Drer\serpinc1, Drer\serpine2, Drer\si:ch211-186e20.7, Drer\serpinf2a, Drer\serpinf2b, Drer\zgc:173729" - "Cele\srp-3, Cele\C28G1.2, Cele\srp-6, Cele\srp-7, Cele\srp-8, Cele\srp-2, Cele\srp-1" "Xtro\serpina1, Xtro\serpinb4, Xtro\serpini1, Xtro\serpinb1, Xtro\serpinc1, Xtro\serpinb11, Xtro\serpina10, Xtro\serpinb6, Xtro\serpine2, Xtro\serpina3m, Xtro\serpinb5, Xtro\serpini2, Xtro\serpina3k, Xtro\serpine1, Xtro\serpind1, Xtro\serpina3" "Mmus\Serpina3i, Mmus\Serpina3f, Mmus\Serpinb2, Mmus\Serpina3c, Mmus\Agt, Mmus\Serpina3n, Mmus\Serpinb6a, Mmus\Serpina7, Mmus\Serpinb9e, Mmus\Serpina3j, Mmus\Serpini1, Mmus\Serpinb11, Mmus\Serpinb5, Mmus\Serpine1, Mmus\Serpina6, Mmus\Serpina9, Mmus\Serpina1e, Mmus\Serpinb6c, Mmus\Serpina1c, Mmus\Serpini2, Mmus\Serpina3a, Mmus\Serpina12, Mmus\Serpine2, Mmus\Serpinb6e, Mmus\Serpina3g, Mmus\Serpinb1b, Mmus\Serpinb6b, Mmus\Serpinb13, Mmus\Serpinb8, Mmus\Serpinc1, Mmus\Serpinb9d, Mmus\Serpinb7, Mmus\Gm11397, Mmus\Serpinb3a, Mmus\Serpinb9c, Mmus\Serpina10, Mmus\Serpinf1, Mmus\Serpina11, Mmus\Serpina1a, Mmus\Serpinb1a, Mmus\Serpinb9b, Mmus\Serpinb1c, Mmus\Serpina16, Mmus\Serpina1d, Mmus\Serpina5, Mmus\Serpinb9, Mmus\Serpinb3d, Mmus\Serpinb9g, Mmus\Serpind1, Mmus\Serpina3k, Mmus\Serpinf2, Mmus\Serpinb12, Mmus\Serpinb9f, Mmus\Serpinb6d, Mmus\Serpinb3c, Mmus\Serpine3" "Hsap\SERPINE2, Hsap\SERPINE3, Hsap\SERPINB11, Hsap\SERPIND1, Hsap\SERPINF2, Hsap\SERPINB6, Hsap\SERPINA9, Hsap\SERPINI2, Hsap\SERPINI1, Hsap\SERPINA5, Hsap\SERPINA1, Hsap\SERPINB9, Hsap\SERPINB8, Hsap\SERPINA7, Hsap\AGT, Hsap\SERPINB5, Hsap\SERPINA3, Hsap\SERPINB1, Hsap\SERPINC1, Hsap\SERPINA12, Hsap\SERPINA6, Hsap\SERPINA11, Hsap\SERPINE1, Hsap\SERPINB10, Hsap\SERPINB12, Hsap\SERPINB2, Hsap\SERPINA10, Hsap\SERPINF1, Hsap\SERPINA4, Hsap\SERPINB4, Hsap\SERPINB7, Hsap\SERPINB13" viable FBgn0040933 CG15315 - http://flybase.org/reports/FBgn0040933 protein_coding_gene - - - CG15315 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036421 CG13481 - http://flybase.org/reports/FBgn0036421 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:25539 zinc ion binding ; GO:0008270 | inferred from sequence model protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:25539 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:25539 CG13481 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13481 11-Aug-17 DroID_v2017_08 Drer\rfwd3 - Cele\T01G5.7 Xtro\rfwd3 Mmus\Rfwd3 Hsap\RFWD3 "viable,body color defective" mesothoracic tergum FBgn0267498 18SrRNA:CR45838 18S ribosomal RNA:CR45838 http://flybase.org/reports/FBgn0267498 rRNA_gene - - - "18SrRNA:CR45838, CR45838" - CR45838 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031730 CG7236 - http://flybase.org/reports/FBgn0031730 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with HGNC:11411" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:11411 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | non-traceable author statement nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:11411 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:11411 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 "KKIALRE, AC018104, CG7236, CG7236/Cdk1l" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG7236 11-Aug-17 DroID_v2017_08 "Drer\cdkl5, Drer\cdkl1" Scer\KIN28 Cele\cdkl-1 "Xtro\cdkl1, Xtro\cdkl5, Xtro\cdkl2" "Mmus\Cdkl4, Mmus\Cdkl3, Mmus\Cdkl5, Mmus\Cdkl1, Mmus\Cdkl2" "Hsap\CDKL4, Hsap\CDKL5, Hsap\CDKL3, Hsap\CDKL1, Hsap\CDKL2" FBgn0027113 mei-P44 mei-P44 http://flybase.org/reports/FBgn0027113 - gene - - - mei-P44 - - 11-Aug-17 DroID_v2017_08 - - - - - - meiotic cell cycle defective FBgn0053440 5SrRNA:CR33440 5SrRNA:CR33440 http://flybase.org/reports/FBgn0053440 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33440, 5SrRNA:CR33440" - CR33440 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000376 crm cramped http://flybase.org/reports/FBgn0000376 - protein_coding_gene DNA binding ; GO:0003677 | non-traceable author statement chromatin binding ; GO:0003682 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement segment specification ; GO:0007379 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "CG2714, EG:95B7.2, zw-9, swa, zw9, l(1)zw9, sa, ZW-9, l(1)3C1, sta[P], l(1)3Ca, crm" IPR001005:SANT/Myb domain CG2714 11-Aug-17 DroID_v2017_08 Drer\cramp1 - Cele\R151.8 Xtro\cramp1 Mmus\Cramp1l Hsap\CRAMP1 " embryonic stage , larval stage | third instar , embryonic stage | early " " pole cell

, embryonic nervous system

, embryonic/larval salivary gland

, gonad

" "viable,fertile,wild-type,lethal,recessive,male sterile,visible,female sterile,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage,male,reduced,male fertile,female,poor,female fertile,partially,maternal effect,polyphasic,eye color defective,body color defective,sterile,suppressor of variegation,dominant,temperature conditional,size defective" "sex comb & prothoracic tarsal segment 2,sex comb & mesothoracic tarsal segment 2,postvertical bristle,wing,arista,antenna,third segment of antenna,sex comb,ectopic,ovary,prothoracic leg,mesothoracic leg,metathoracic leg,eye,tarsal segment 2,ovariole,germline clone,leg,prothoracic tarsal segment 2,pigment cell,supernumerary,temperature conditional,adult abdomen,wing margin,wing disc,adult thorax" FBgn0264286 Su(Mir)1F2-3 - http://flybase.org/reports/FBgn0264286 gene - - - Su(Mir)1F2-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028694 Rpn11 Regulatory particle non-ATPase 11 http://flybase.org/reports/FBgn0028694 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with SGD:S000001900 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with SGD:S000001900 "proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000001900 microtubule associated complex ; GO:0005875 | inferred from direct assay" "p37B, yip5, S13, CG18174, Rpn11, RPn11, RPN11, rpn11, DmS13, 37B, Q9V3H2, PSMD14" "IPR024969:Rpn11/EIF3F, C-terminal, IPR000555:JAB1/MPN/MOV34 metalloenzyme domain" CG18174 11-Aug-17 DroID_v2017_08 "Drer\brcc3, Drer\psmd14, Drer\mpnd, Drer\mysm1" "Scer\RPN11, Scer\RRI1" "Cele\rpn-11, Cele\F37A4.5" "Xtro\psmd14, Xtro\mysm1, Xtro\brcc3, Xtro\mpnd" "Mmus\Mpnd, Mmus\Mysm1, Mmus\Brcc3, Mmus\Psmd14" "Hsap\PSMD14, Hsap\MPND, Hsap\BRCC3, Hsap\MYSM1" "lethal - all die before end of larval stage,some die during larval stage,lethal,short lived,visible,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere,progressive,eye,wing,wing margin bristle" DRSC03422 IEK -3.097075604 -2.940798446 -4.987137804 -3.422478875 -0.45211326 -1.711354921 FBgn0013242 E(var)231 E(var)231 http://flybase.org/reports/FBgn0013242 - gene - - - E(var)231 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0061064 l(3)S021204b lethal (3) S021204b http://flybase.org/reports/FBgn0061064 gene - - - "0212/04, l(3)S021204b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0021925 l(2)k11206 lethal (2) k11206 http://flybase.net/reports/FBgn0021925.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0054031 CG34031 - http://flybase.org/reports/FBgn0054031 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG34031, BP1068, CR34031" "IPR020479:Homeobox domain, metazoa, IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG34031 11-Aug-17 DroID_v2017_08 "Drer\nkx1.2lb, Drer\ved, Drer\tlx1, Drer\barx1, Drer\barhl1b, Drer\lbx2, Drer\tlx3b, Drer\dbx1b, Drer\barx2, Drer\vox, Drer\tlx2, Drer\barhl2, Drer\lbx1a, Drer\lbx1b, Drer\LOC100008066, Drer\pnx, Drer\hlx1" - Cele\ceh-19 "Xtro\ventx1.2, Xtro\tlx2, Xtro\dbx1, Xtro\nkx1-1, Xtro\tlx3, Xtro\barhl1, Xtro\tlx1, Xtro\nkx1-2, Xtro\hlx, Xtro\barx1, Xtro\barhl2" "Mmus\Tlx1, Mmus\Tlx3, Mmus\Lbx2, Mmus\Nkx1-2, Mmus\Barhl1, Mmus\Tlx2, Mmus\Barx1, Mmus\Lbx1, Mmus\Hlx, Mmus\Barx2, Mmus\Dbx2, Mmus\Nkx1-1, Mmus\Dbx1, Mmus\Barhl2" "Hsap\TLX1, Hsap\HLX, Hsap\TLX2, Hsap\DBX1, Hsap\NKX1-1, Hsap\DBX2, Hsap\BARX2, Hsap\BARX1, Hsap\BARHL2, Hsap\LBX2, Hsap\LBX1, Hsap\TLX3, Hsap\BARHL1" FBgn0085687 CG41556 - http://flybase.org/reports/FBgn0085687 protein_coding_gene - - - CG41556 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027607 CG8230 - http://flybase.org/reports/FBgn0027607 - protein_coding_gene - Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000307154 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000307154 "BcDNA:GH02536, CG8230" "IPR019142:Dymeclin, IPR011989:Armadillo-like helical" CG8230 11-Aug-17 DroID_v2017_08 Drer\dym - Cele\C47D12.2 Xtro\dym Mmus\Dym Hsap\DYM viable FBgn0036290 CG10638 - http://flybase.org/reports/FBgn0036290 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" - "anon-WO0172774.89, CG32101, CG10638, AKR" "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG10638 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-180p18.9, Drer\akr1b1, Drer\akr1a1a, Drer\zgc:56622, Drer\zgc:110366, Drer\akr1a1b, Drer\zgc:101765, Drer\zgc:110782" "Scer\YDL124W, Scer\ARA1, Scer\GCY1, Scer\GRE3, Scer\YJR096W, Scer\YPR1" "Cele\K07C5.2, Cele\ZC443.1, Cele\F53F1.2, Cele\T08H10.1, Cele\Y39G8B.1, Cele\C07D8.6, Cele\Y39G8B.2, Cele\C56G3.2, Cele\F53F1.3, Cele\C01G5.5, Cele\C35D10.6, Cele\ZK1290.5" "Xtro\LOC548351, Xtro\akr1b1, Xtro\akr1c1, Xtro\akr1d1, Xtro\akr1c2, Xtro\akr1a1, Xtro\akr1c8p" "Mmus\Akr1b8, Mmus\Akr1c13, Mmus\Akr1c12, Mmus\Akr1d1, Mmus\Akr1c18, Mmus\Akr1c14, Mmus\Akr1b3, Mmus\Akr1c21, Mmus\Akr1c6, Mmus\Akr1cl, Mmus\Akr1c20, Mmus\Akr1c19, Mmus\Akr1a1, Mmus\Akr1b10, Mmus\Akr1b7, Mmus\Akr1e1" "Hsap\AKR1C3, Hsap\AKR1E2, Hsap\AKR1B1, Hsap\AKR1B10, Hsap\AKR1C1, Hsap\AKR1C2, Hsap\AKR1A1, Hsap\AKR1C4, Hsap\AKR1B15, Hsap\AKR1D1" "viable,fertile" DRSC09762 E 1.455188505 0.610534036 3.778715186 0.730468809 0.005748208 0.969895056 FBgn0051526 CR31526 - http://flybase.org/reports/FBgn0051526 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31526, CR31526" - CR31526 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263260 sel seele http://flybase.org/reports/FBgn0263260 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "enzyme linked receptor protein signaling pathway ; GO:0007167 | inferred from biological aspect of ancestor with PANTHER:PTN001000330 polarity specification of dorsal/ventral axis ; GO:0009951 | inferred from mutant phenotype regulation of protein processing ; GO:0070613 | inferred from mutant phenotype tissue development ; GO:0009888 | inferred from biological aspect of ancestor with PANTHER:PTN001000330 maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | inferred from mutant phenotype regulation of protein secretion ; GO:0050708 | inferred from mutant phenotype" endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "sel, CG12918, Sle" IPR021852:Domain of unknown function DUF3456 CG12918 11-Aug-17 DroID_v2017_08 "Drer\cnpy1, Drer\cnpy2" - "Cele\Y47H9C.8, Cele\F01F1.11, Cele\F01F1.15" "Xtro\cnpy1, Xtro\cnpy2" "Mmus\Cnpy1, Mmus\Cnpy2" "Hsap\CNPY2, Hsap\CNPY1" FBgn0037151 CG7130 - http://flybase.org/reports/FBgn0037151 protein_coding_gene - - - CG7130 "IPR001623:DnaJ domain, IPR018253:DnaJ domain, conserved site" CG7130 11-Aug-17 DroID_v2017_08 "Drer\dnajb1b, Drer\dnajb5, Drer\zgc:122979, Drer\dnajb12a, Drer\dnajc18, Drer\dnajc5ab, Drer\dnajb12b, Drer\dnajb2, Drer\dnajc5aa, Drer\im:7136940, Drer\dnajb14, Drer\dnajc5b, Drer\dnajc5gb, Drer\dnajc22, Drer\dnajc5ga, Drer\dnajb1a, Drer\dnajb4, Drer\dnajb9a" "Scer\SIS1, Scer\JJJ2, Scer\XDJ1, Scer\APJ1, Scer\HLJ1, Scer\JJJ1, Scer\SCJ1, Scer\ERJ5, Scer\CWC23" "Cele\dnj-12, Cele\dnj-26, Cele\dnj-14, Cele\F54F2.9, Cele\dnj-19, Cele\dnj-22, Cele\dnj-13, Cele\dnj-1" "Xtro\dnajb1, Xtro\dnajc22, Xtro\dnajb5, Xtro\dnajb12, Xtro\dnajb2, Xtro\dnajb6, Xtro\dnajc5g, Xtro\dnajb13, Xtro\dnajb4, Xtro\dnajb9, Xtro\dnajb14, Xtro\dnajc18" "Mmus\Dnajc5b, Mmus\Dnajc5, Mmus\Dnajb7, Mmus\Dnajb8, Mmus\Dnajb1, Mmus\Dnajb6, Mmus\Dnajb12, Mmus\Dnajb3, Mmus\Dnajc21, Mmus\Dnajb4, Mmus\Dnajc5g, Mmus\Dnajc22, Mmus\Dnajb14, Mmus\Dnajb2, Mmus\Dnajc18, Mmus\Dnajb5, Mmus\Dnajb9, Mmus\Dnajb13" "Hsap\DNAJC22, Hsap\DNAJB13, Hsap\DNAJB12, Hsap\DNAJB3, Hsap\DNAJB4, Hsap\DNAJB7, Hsap\DNAJB2, Hsap\DNAJB1, Hsap\DNAJC5G, Hsap\DNAJB14, Hsap\DNAJC5B, Hsap\DNAJB5, Hsap\DNAJB6, Hsap\DNAJC18, Hsap\DNAJB9, Hsap\DNAJC5, Hsap\DNAJB8" viable FBgn0015379 dod dodo http://flybase.org/reports/FBgn0015379 - protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from sequence or structural similarity with HGNC:8988 inferred from sequence or structural similarity with SGD:S000003778 regulation of locomotor rhythm ; GO:1904059 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Pin1, CG17051, dod" "IPR000297:Peptidyl-prolyl cis-trans isomerase, PpiC-type, IPR001202:WW domain, IPR023058:Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site" CG17051 11-Aug-17 DroID_v2017_08 Drer\pin1 Scer\ESS1 "Cele\Y40B1A.2, Cele\pinn-1" Xtro\pin1 "Mmus\Pin1rt1, Mmus\Pin1" Hsap\PIN1 viable FBgn0020771 wv wv http://flybase.org/reports/FBgn0020771 - gene - - - wv - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0002089 l(2)55i lethal (2) 55i http://flybase.org/reports/FBgn0002089 - gene - - - l(2)55i - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0267495 CR45185 - http://flybase.org/reports/FBgn0267495 non_protein_coding_gene - - - "CR45185, CR45219" - CR45185 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005247 l(3)R200 lethal of Roberts 200 http://flybase.org/reports/FBgn0005247 - gene - - - "l(3)200, l(3)R200" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0086706 pix pixie http://flybase.org/reports/FBgn0086706 protein_coding_gene "ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATP binding ; GO:0005524 | inferred from mutant phenotype iron ion binding ; GO:0005506 | inferred from biological aspect of ancestor with PANTHER:PTN000443727 translation initiation factor binding ; GO:0031369 | inferred from physical interaction with UniProtKB:Q0E940 inferred from physical interaction with UniProtKB:Q7K550 ribosomal small subunit binding ; GO:0043024 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCK0" "nuclear-transcribed mRNA catabolic process, non-stop decay ; GO:0070481 | inferred from genetic interaction with pcm translation ; GO:0006412 | inferred from mutant phenotype ribosome disassembly ; GO:0032790 | inferred from sequence or structural similarity with SGD:S000002498 negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype ribosomal subunit export from nucleus ; GO:0000054 | inferred from biological aspect of ancestor with PANTHER:PTN000443727 translational initiation ; GO:0006413 | inferred from mutant phenotype translational termination ; GO:0006415 | inferred from biological aspect of ancestor with PANTHER:PTN000443727 cell growth ; GO:0016049 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | colocalizes_with inferred from direct assay "CG5651, E3-c, BEST:GH18088, pix, ABCE1" "IPR013283:RLI1, IPR007209:RNase L inhibitor RLI, possible metal-binding domain, IPR003593:AAA+ ATPase domain, IPR003439:ABC transporter-like, IPR017871:ABC transporter, conserved site, IPR017896:4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR017900:4Fe-4S ferredoxin, iron-sulphur binding, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR034348:RLI, domain 1" CG5651 11-Aug-17 DroID_v2017_08 Drer\abce1 Scer\RLI1 Cele\abce-1 Xtro\abce1 Mmus\Abce1 Hsap\ABCE1 DRSC10533 EK -0.717102901 0.220478252 1.733002634 -1.354949744 -0.31188342 2.370738049 FBgn0260482 CG32599 - http://flybase.org/reports/FBgn0260482 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12047, GM07807, CG32599" - CG32599 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031782 WDR79 WD repeat domain 79 http://flybase.org/reports/FBgn0031782 protein_coding_gene box C/D snoRNA binding ; GO:0034512 | inferred from direct assay Cajal body organization ; GO:0030576 | inferred from mutant phenotype Cajal body ; GO:0015030 | inferred from direct assay "WDR79, p70, CG9226, dWDR79" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG9226 11-Aug-17 DroID_v2017_08 Drer\wrap53 Scer\SWT21 Cele\Y105E8A.8 - Mmus\Wrap53 Hsap\WRAP53 "viable,fertile" "Cajal body,Cajal bodyda.PU" FBgn0060555 l(3)S097408 lethal (3) S097408 http://flybase.org/reports/FBgn0060555 gene - - - "0974/08, l(3)S097408" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002966 nr nesher http://flybase.org/reports/FBgn0002966 - gene - - - nr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033773 Mos Mos oncogene http://flybase.org/reports/FBgn0033773 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 kinase activity ; GO:0016301 | inferred from mutant phenotype protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN002356424 protein kinase activity ; GO:0004672 | inferred from genetic interaction with Tsc1" oocyte development ; GO:0048599 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype cell cycle arrest ; GO:0007050 | inferred from mutant phenotype negative regulation of metaphase/anaphase transition of meiotic cell cycle ; GO:1902103 | inferred from biological aspect of ancestor with PANTHER:PTN001147960 positive regulation of MAPK cascade ; GO:0043410 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from genetic interaction with Tsc1 positive regulation of TOR signaling ; GO:0032008 | inferred from genetic interaction with Tsc1 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001147960 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:97052 "dmos, DMOS, CG8767, D-mos, MOS, mos, Mos" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG8767 11-Aug-17 DroID_v2017_08 "Drer\ripk3, Drer\lrrk2, Drer\zak, Drer\dstyk, Drer\ripk2, Drer\map3k9, Drer\ripk1l, Drer\pbk, Drer\si:ch211-120p12.3, Drer\ripk4, Drer\map3k10, Drer\LOC405768, Drer\mos" Scer\SWE1 - "Xtro\ripk4, Xtro\ankk1, Xtro\zak, Xtro\map3k7, Xtro\map3k9, Xtro\LOC100490493, Xtro\ripk1, Xtro\pbk, Xtro\dstyk, Xtro\mlkl, Xtro\lrrk1, Xtro\lrrk2, Xtro\map3k10" "Mmus\Ripk2, Mmus\Map3k9, Mmus\Map3k7, Mmus\Mos, Mmus\BC021891, Mmus\Lrrk1, Mmus\Mlkl, Mmus\Map3k11, Mmus\Ripk3, Mmus\Ripk4, Mmus\Ripk1, Mmus\Zak, Mmus\Dstyk, Mmus\Pbk, Mmus\Lrrk2, Mmus\Map3k10" "Hsap\MAP3K10, Hsap\MAP3K11, Hsap\RIPK3, Hsap\MAP3K20, Hsap\MLKL, Hsap\LRRK1, Hsap\DSTYK, Hsap\MAP3K21, Hsap\MOS, Hsap\RIPK2, Hsap\LRRK2, Hsap\PBK, Hsap\RIPK4, Hsap\MAP3K9, Hsap\MAP3K7, Hsap\RIPK1" "viable,male fertile,female semi-sterile,increased cell death" ovary DRSC07258 E -1.015046391 0.321482375 -1.737465678 0.759144058 -0.176972329 0.108918286 FBgn0266355 CR45003 - http://flybase.org/reports/FBgn0266355 non_protein_coding_gene - - - CR45003 - CR45003 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014140 chec che caos http://flybase.org/reports/FBgn0014140 - gene - - - chec - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,male sterile,female sterile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" spindle FBgn0036734 CG7564 - http://flybase.org/reports/FBgn0036734 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000271979 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002245 inferred from sequence or structural similarity with protein_id:BAA91737 mRNA splice site selection ; GO:0006376 | inferred from biological aspect of ancestor with PANTHER:PTN000271979" U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000271979 precatalytic spliceosome ; GO:0071011 | inferred from direct assay U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity with SGD:S000002245 inferred from sequence or structural similarity with protein_id:BAA91737 U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000271979 "CG7564, Alsin2" IPR004882:Luc7-related CG7564 11-Aug-17 DroID_v2017_08 "Drer\zgc:158803, Drer\luc7l, Drer\luc7l3" Scer\LUC7 "Cele\Y119D3B.12, Cele\B0495.8, Cele\C50D2.8" "Xtro\luc7l2, Xtro\luc7l3, Xtro\luc7l" "Mmus\Luc7l3, Mmus\Luc7l, Mmus\Luc7l2" "Hsap\LUC7L2, Hsap\LUC7L3, Hsap\LUC7L" "viable,visible" mesothoracic tergum DRSC10880 IK 2.576048087 -0.637347914 0.285858667 -0.447730023 1.560449189 1.597239532 FBgn0069412 JJF171 JJF171 http://flybase.org/reports/FBgn0069412 gene - - - JJF171 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0262766 Mst77Y-18Psi Male-specific pseudogene 77Y 18 http://flybase.org/reports/FBgn0262766 pseudogene_attribute - - - Mst77Y-18Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027350 anon-93Bc anon-93Bc http://flybase.org/reports/FBgn0027350 - gene - - - anon-93Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005244 l(3)R138 lethal of Roberts 138 http://flybase.org/reports/FBgn0005244 - gene - - - "l(3)138, l(3)R138" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0082907 Alh::Hsap\KMT2A MLL http://flybase.org/reports/FBgn0082907 engineered_fusion_gene - - - "Alh::Hsap\MLL, Alh::Hsap\KMT2A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259537 GG01510 - http://flybase.org/reports/FBgn0259537 gene - - - GG01510 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,leg,arista,wing,third segment of antenna" FBgn0266654 CR45161 - http://flybase.org/reports/FBgn0266654 non_protein_coding_gene - - - CR45161 - CR45161 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005716 l(1)TK121 lethal (1) TK121 http://flybase.org/reports/FBgn0005716 - gene - - - "l121, l(1)TK121" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0267749 CR46080 - http://flybase.org/reports/FBgn0267749 non_protein_coding_gene - - - CR46080 - CR46080 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263343 CR43424 - http://flybase.org/reports/FBgn0263343 non_protein_coding_gene - - - CR43424 - CR43424 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082934 snoRNA:Me28S-G1083b snoRNA:Me28S-G1083b http://flybase.org/reports/FBgn0082934 snoRNA_gene rRNA 2'-O-ribose methylation guide activity ; GO:0030562 | inferred from sequence model rRNA 2'-O-methylation ; GO:0000451 | inferred from sequence model nucleolus ; GO:0005730 | inferred from direct assay "snoRNA:Me28S-G1083b, Me28S-Gm1083b, CR34563, DmSnR60, DmSnR60b" - CR34563 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266383 CR45025 - http://flybase.org/reports/FBgn0266383 non_protein_coding_gene - - - CR45025 - CR45025 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030354 Upf1 Upf1 http://flybase.org/reports/FBgn0030354 protein_coding_gene helicase activity ; GO:0004386 | inferred from electronic annotation with InterPro:IPR018999 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR018999 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR018999 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018999 "positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:2000624 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | NOT inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype RNA interference ; GO:0016246 | NOT inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR018999 exon-exon junction complex ; GO:0035145 | colocalizes_with inferred from direct assay "UPF1, CG1559, DmUpf1, Dm-Upf1, Upf1, upf1, Upf1p, smg-2" "IPR018999:RNA helicase UPF1, UPF2-interacting domain, IPR006935:Helicase/UvrB, N-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1559 11-Aug-17 DroID_v2017_08 Drer\upf1 "Scer\ECM32, Scer\NAM7" Cele\smg-2 "Xtro\upf1, Xtro\zgrf1" "Mmus\Zgrf1, Mmus\Upf1" "Hsap\ZGRF1, Hsap\UPF1" "lethal - all die before end of larval stage,lethal,mitotic cell cycle defective,germline clone,lethal - all die before end of second instar larval stage,male limited,some die during second instar larval stage,some die during third instar larval stage" "adult tracheal system,somatic clone,eye,dorsal appendage,germline clone,follicle cell" DRSC19667 I -0.535036313 -2.556182212 -0.817297391 -1.353204726 0.717216744 0.213075128 FBgn0032553 CG4480 - http://flybase.org/reports/FBgn0032553 protein_coding_gene - - - CG4480 - CG4480 11-Aug-17 DroID_v2017_08 - - "Cele\srd-56, Cele\C46E10.2" - - - "partially lethal - majority die,some die during pupal stage" FBgn0002396 l(3)93Fc lethal (3) 93Fc http://flybase.org/reports/FBgn0002396 - gene - - - "er18, l(3)er18, l(3)93Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,female sterile,lethal,partially" wing FBgn0037383 CG2023 - http://flybase.org/reports/FBgn0037383 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with HGNC:1082 endoplasmic reticulum membrane fusion ; GO:0016320 | inferred from sequence or structural similarity with HGNC:1082 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with HGNC:1082 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:1082 "CG2023, Cg2023, lincRNA.683, Sec20" IPR005606:Sec20 CG2023 11-Aug-17 DroID_v2017_08 "Drer\bnip1a, Drer\bnip1b" Scer\SEC20 Cele\sec-20 Xtro\bnip1 Mmus\Bnip1 Hsap\BNIP1 FBgn0036214 CG7264 - http://flybase.org/reports/FBgn0036214 protein_coding_gene - - - CG7264 IPR008805:RIB43A CG7264 11-Aug-17 DroID_v2017_08 "Drer\ribc2, Drer\ribc1, Drer\cfap53" - - "Xtro\ribc1, Xtro\ribc2" "Mmus\Ribc2, Mmus\Ribc1" "Hsap\RIBC2, Hsap\RIBC1" viable FBgn0266706 CR45196 - http://flybase.org/reports/FBgn0266706 non_protein_coding_gene - - - CR45196 - CR45196 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250749 alpha-Spec::beta-Spec - http://flybase.org/reports/FBgn0250749 engineered_fusion_gene - - - alpha-Spec::beta-Spec - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001414 l(1)3Ed lethal (1) 3Ed http://flybase.org/reports/FBgn0001414 - gene - - - "JC43, l(1)GA58, l(1)GA2, l(1)3Ed" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260351 GSd489 - http://flybase.org/reports/FBgn0260351 gene - - - GSd489 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010588 l(2)05006 lethal (2) 05006 http://flybase.org/reports/FBgn0010588 - gene - - - l(2)05006 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260056 2L3918 - http://flybase.org/reports/FBgn0260056 gene - - - 2L3918 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0002047 l(2)37Ea lethal (2) 37Ea http://flybase.org/reports/FBgn0002047 - gene - - - "l(2)E124, l(2)37Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,recessive" FBgn0011740 alpha-Man-IIa alpha-Mannosidase class II a http://flybase.org/reports/FBgn0011740 "FBgn0037691, FBgn0042203" protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR015341 mannosidase activity ; GO:0015923 | inferred from direct assay alpha-mannosidase activity ; GO:0004559 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 protein deglycosylation ; GO:0006517 | inferred from mutant phenotype encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype mannose metabolic process ; GO:0006013 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 protein deglycosylation ; GO:0006517 | inferred from direct assay N-glycan processing ; GO:0006491 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000176398 endoplasmic reticulum ; GO:0005783 | non-traceable author statement Golgi stack ; GO:0005795 | non-traceable author statement "dGMIIb, dGMII, GMII, DM-GII.1, GmII, MAN-2, alpha-Man-II, CG8139, CG18474, CG18802, Man, Man-II, alpha-Man-IIa" "IPR000602:Glycoside hydrolase family 38, N-terminal domain, IPR011013:Galactose mutarotase-like domain, IPR011682:Glycosyl hydrolase family 38, C-terminal, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR015341:Glycoside hydrolase family 38, central domain, IPR028995:Glycoside hydrolase families 57/38, central domain, IPR027291:Glycoside hydrolase 38/57, N-terminal domain" CG18802 11-Aug-17 DroID_v2017_08 "Drer\man2b1, Drer\man2a1, Drer\man2a2, Drer\man2b2" Scer\AMS1 "Cele\aman-1, Cele\aman-3, Cele\aman-2" "Xtro\man2b1, Xtro\man2a1, Xtro\man2a2, Xtro\man2b2" "Mmus\Man2a1, Mmus\Man2b2, Mmus\Man2b1, Mmus\Man2c1, Mmus\Man2a2" "Hsap\MAN2C1, Hsap\MAN2A2, Hsap\MAN2B1, Hsap\MAN2A1, Hsap\MAN2B2" "visible,long lived,viable,immune response defective" eye FBgn0005015 dipp-6 defective in phototaxis plasticity 6 http://flybase.org/reports/FBgn0005015 - gene - - - dipp-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,mating defective,female,visual behavior defective,phototaxis defective" photoreceptor FBgn0065985 iab-4-2.s iab-4-2.s http://flybase.org/reports/FBgn0065985 gene - - - "4-2 s, iab-4-2.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061502 l(2)44Fn lethal (2) 44Fn http://flybase.org/reports/FBgn0061502 gene - - - l(2)44Fn - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005409 l(1)11Ai lethal (1) 11Ai http://flybase.org/reports/FBgn0005409 - gene - - - l(1)11Ai - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065611 l(2)SH0837 lethal (2) SH0837 http://flybase.org/reports/FBgn0065611 gene - - - "l(2)SH0837, l(2)SH2 0837" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060672 l(3)S078708 lethal (3) S078708 http://flybase.org/reports/FBgn0060672 gene - - - "0787/08, l(3)S078708" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0083046 snoRNA:Psi18S-1389a snoRNA:Psi18S-1389a http://flybase.org/reports/FBgn0083046 snoRNA_gene - - - "snoRNA:Psi18S-1389a, psi18s-1389a, Psi 18S-1389a, CR34556, chr2R:16841577..16841810" - CR34556 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266892 CR45352 - http://flybase.org/reports/FBgn0266892 non_protein_coding_gene - - - CR45352 - CR45352 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002546 lfb little faint ball http://flybase.org/reports/FBgn0002546 - gene - dorsal closure ; GO:0007391 | inferred from mutant phenotype - lfb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" dorsal closure embryo FBgn0044100 E(rst)C544 E(rst)C544 http://flybase.org/reports/FBgn0044100 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C544, E(rst)C544" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050277 Oatp58Da Organic anion transporting polypeptide 58Da http://flybase.org/reports/FBgn0050277 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with Oatp58Db active transmembrane transporter activity ; GO:0022804 | inferred from sequence or structural similarity with Oatp58Db organic substance transport ; GO:0071702 | inferred from sequence or structural similarity with Oatp58Db integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Oatp58Db "oatp 58Da, CG3387, CG30277, Oatp58Da" "IPR020846:Major facilitator superfamily domain, IPR004156:Organic anion transporter polypeptide OATP, IPR002350:Kazal domain" CG30277 11-Aug-17 DroID_v2017_08 "Drer\slco3a1, Drer\slco2a1, Drer\slco1c1, Drer\slco5a1, Drer\slco2b1, Drer\slco1f1, Drer\LOC100334356, Drer\LOC100536648, Drer\slco1f4, Drer\LOC101883455, Drer\slco4a1, Drer\slco1d1, Drer\slco1f3, Drer\LOC570448, Drer\slco1f2" - "Cele\F47E1.2, Cele\F21G4.1, Cele\K02G10.5, Cele\F47E1.4, Cele\Y32F6B.1, Cele\F53B1.8, Cele\Y70G10A.3" "Xtro\slco4c1, Xtro\slco4a1, Xtro\slco1b3, Xtro\slco5a1, Xtro\slco2a1, Xtro\slco3a1" "Mmus\Slco5a1, Mmus\Slco1c1, Mmus\Slco3a1, Mmus\Slco6d1, Mmus\Gm6614, Mmus\Slco2a1, Mmus\Slco1a4, Mmus\Slco2b1, Mmus\Slco4a1, Mmus\Slco1a1, Mmus\Slco4c1, Mmus\Slco1b2, Mmus\Slco1a5, Mmus\Slco1a6, Mmus\Gm5724, Mmus\Slco6c1" "Hsap\SLCO6A1, Hsap\SLCO1C1, Hsap\SLCO2A1, Hsap\SLCO4A1, Hsap\SLCO2B1, Hsap\SLCO3A1, Hsap\SLCO4C1, Hsap\SLCO1B1, Hsap\SLCO1B3, Hsap\SLCO1B7, Hsap\SLCO1A2, Hsap\SLCO5A1" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0040977 CG15292 - http://flybase.org/reports/FBgn0040977 protein_coding_gene - - - CG15292 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058230 CG40230 - http://flybase.org/reports/FBgn0058230 protein_coding_gene - - - CG40230 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083012 snoRNA:Psi28S-1135a snoRNA:Psi28S-1135a http://flybase.org/reports/FBgn0083012 snoRNA_gene - - - "snoRNA:Psi28S-1135a, Psi28S-1135a, Psi28S-1135, psi28S-1135a, Psi 28S-1135a, CR34606, chrX:16980527..16980719" - CR34606 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063497 GstE3 Glutathione S transferase E3 http://flybase.org/reports/FBgn0063497 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTE3, CG17524, BEST:GH09055, GstE3, GSTE3, GST-E3, E3, gste3" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17524 11-Aug-17 DroID_v2017_08 "Drer\gstt1a, Drer\eef1g, Drer\eef1e1, Drer\mars, Drer\vars, Drer\gstr, Drer\gstt2, Drer\gstt1b" "Scer\GTT1, Scer\GTT2, Scer\YGR201C, Scer\URE2, Scer\CAM1, Scer\TEF4" "Cele\gst-21, Cele\gst-29" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Mars, Mmus\Eef1g, Mmus\Gstt4, Mmus\Gstt3, Mmus\Eef1e1, Mmus\Gstt1, Mmus\Gstt2, Mmus\Vars" "Hsap\GSTT1, Hsap\EEF1E1, Hsap\GSTT2, Hsap\EEF1G, Hsap\VARS, Hsap\MARS, Hsap\GSTT2B" viable FBgn0038129 TBC1D5 TBC1 domain family member 5 http://flybase.org/reports/FBgn0038129 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab18 inferred from physical interaction with Rab6 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Golgi apparatus ; GO:0005794 | inferred from direct assay "CG8449, TBC1D5" IPR000195:Rab-GTPase-TBC domain CG8449 11-Aug-17 DroID_v2017_08 Drer\tbc1d5 Scer\GYP6 Cele\rbg-3 Xtro\tbc1d5 "Mmus\Tbc1d5, Mmus\Tbc1d21" "Hsap\TBC1D21, Hsap\TBC1D5" viable FBgn0032524 CG9267 - http://flybase.org/reports/FBgn0032524 protein_coding_gene enzyme binding ; GO:0019899 | inferred from sequence or structural similarity with HGNC:24175 fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with HGNC:24175 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:24175 "Q9VJX8, CG9267, HADC[CG9267]" "IPR007052:CS domain, IPR007482:Protein-tyrosine phosphatase-like, PTPLA, IPR008978:HSP20-like chaperone" CG9267 11-Aug-17 DroID_v2017_08 "Drer\hacd3, Drer\hacd2, Drer\ptges3a, Drer\si:ch73-41h24.1, Drer\ptges3b" "Scer\SBA1, Scer\PHS1" "Cele\ZC395.10, Cele\R10E4.9" "Xtro\hacd1, Xtro\hacd3, Xtro\hacd2" "Mmus\Hacd1, Mmus\Hacd4, Mmus\Hacd2, Mmus\Hacd3" "Hsap\HACD4, Hsap\HACD1, Hsap\PTGES3, Hsap\HACD3, Hsap\HACD2" "viable,fertile" FBgn0013298 MT:DNA Mitochondrial DNA http://flybase.org/reports/FBgn0013298 FBgn0003457 mitochondrial_sequence - - - "mtDNA, MtDNA, MT:DNA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261919 Amph::EndoA - http://flybase.org/reports/FBgn0261919 engineered_fusion_gene - - - "Amph::endoA, Amph::EndoA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013466 grunt grunt http://flybase.org/reports/FBgn0013466 - gene molecular_function ; GO:0003674 | no biological data available grooming behavior ; GO:0007625 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available grunt - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive,behavior defective" FBgn0029178 E(Khc)ek9 E(Khc)ek9 http://flybase.org/reports/FBgn0029178 gene - - - E(Khc)ek9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002490 l(3)SG50 lethal (3) SG50 http://flybase.org/reports/FBgn0002490 - gene - - - "l(3)7m-75, l(3)SG50" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0033460 Sec24AB Secretory 24AB http://flybase.org/reports/FBgn0033460 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006895 transporter activity ; GO:0005215 | inferred by curator from GO:0030127,GO:0090110 signal sequence binding ; GO:0005048 | inferred from sequence or structural similarity with SGD:S000001371" "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR006895, InterPro:IPR006896, InterPro:IPR006900 cargo loading into COPII-coated vesicle ; GO:0090110 | inferred from sequence or structural similarity with SGD:S000001371" COPII vesicle coat ; GO:0030127 | inferred from sequence or structural similarity with SGD:S000001371 "CG1472, Sec24, SEC24, Sec24AB, sec24, Hau" "IPR006895:Zinc finger, Sec23/Sec24-type, IPR006896:Sec23/Sec24, trunk domain, IPR006900:Sec23/Sec24, helical domain, IPR007123:Gelsolin-like domain, IPR012990:Sec23/Sec24 beta-sandwich, IPR002035:von Willebrand factor, type A, IPR029006:ADF-H/Gelsolin-like domain" CG1472 11-Aug-17 DroID_v2017_08 "Drer\sec24c, Drer\sec24d, Drer\sec24a, Drer\sec24b" "Scer\SEC24, Scer\SFB2, Scer\SFB3" Cele\sec-24.2 "Xtro\sec24b, Xtro\sec24a, Xtro\sec24d" "Mmus\Sec24d, Mmus\Sec24b, Mmus\Sec24a, Mmus\Sec24c" "Hsap\SEC24C, Hsap\SEC24A, Hsap\SEC24B, Hsap\SEC24D" viable FBgn0025006 E(var)129-1 E(var)129-1 http://flybase.org/reports/FBgn0025006 - gene - - - "E-129/1, E(var)129-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004157 l(2)Ta lethal (2) with Thickened arista http://flybase.org/reports/FBgn0004157 - gene - - - l(2)Ta - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage" FBgn0003353 sei seizure http://flybase.org/reports/FBgn0003353 - protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | non-traceable author statement voltage-gated cation channel activity ; GO:0022843 | inferred from sequence or structural similarity with eag voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | non-traceable author statement regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 potassium ion transport ; GO:0006813 | inferred from sequence or structural similarity with eag voltage-gated potassium channel complex ; GO:0008076 | inferred from sequence or structural similarity with eag integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 voltage-gated potassium channel complex ; GO:0008076 | non-traceable author statement "Derg, erg, CG3182, sei" "IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR003938:Potassium channel, voltage-dependent, EAG/ELK/ERG, IPR003967:Potassium channel, voltage-dependent, ERG, IPR005821:Ion transport domain, IPR014710:RmlC-like jelly roll fold" CG3182 11-Aug-17 DroID_v2017_08 "Drer\kcnh1a, Drer\kcnh1b, Drer\kcnh8, Drer\kcnh5a, Drer\hcn4l, Drer\hcn3, Drer\kcnh5b, Drer\LOC101883600, Drer\kcnh6a, Drer\kcnh4b, Drer\si:rp71-68n21.12, Drer\kcnh3, Drer\kcnh6b, Drer\kcnh4a, Drer\hcn2b, Drer\LOC100334297, Drer\kcnh7, Drer\hcn4, Drer\kcnh2a" - Cele\unc-103 "Xtro\hcn1, Xtro\kif23, Xtro\kcnh7, Xtro\kcnh6, Xtro\hcn4, Xtro\kcnh1, Xtro\kcnh8" "Mmus\Hcn4, Mmus\Kcnh4, Mmus\Hcn1, Mmus\Kif23, Mmus\Kcnh7, Mmus\Hcn2, Mmus\Hcn3, Mmus\Kcnh6, Mmus\Kcnh8, Mmus\Kcnh3, Mmus\Kcnh2, Mmus\Kcnh5, Mmus\Kcnh1" "Hsap\KCNH6, Hsap\KIF23, Hsap\KCNH8, Hsap\KCNH3, Hsap\KCNH4, Hsap\KCNH5, Hsap\KCNH1, Hsap\KCNH7, Hsap\KCNH2, Hsap\HCN1, Hsap\HCN3, Hsap\HCN4, Hsap\HCN2" " adult stage , embryonic stage " embryonic central nervous system

"neuroanatomy defective,heat sensitive,visible,wild-type,paralytic,behavior defective,temperature conditional,neurophysiology defective,codominant,viable,locomotor behavior defective,auditory perception defective,lethal" "neuromuscular junction,NMJ bouton,supernumerary,heat sensitive,neuromuscular junction | heat sensitive,ectopic,eye,neuromuscular junction & synapse,synapse | ectopic | heat sensitive,adult central nervous system,neuromuscular junction | temperature conditional,temperature conditional,dorsal medial muscle,adult brain,motor neuron" FBgn0002279 l(3)73Ad lethal (3) 73Ad http://flybase.org/reports/FBgn0002279 - gene - - - "l(3)std8, l(3)73Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0036503 CG13454 - http://flybase.org/reports/FBgn0036503 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13454 - CG13454 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0046320 roX2-CES roX2 chromatin entry site http://flybase.org/reports/FBgn0046320 region - - - "roX2-CES, CES" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052011 CR32011 - http://flybase.org/reports/FBgn0052011 pseudogene_attribute - - - "CG32011, CR32011" - CR32011 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036112 CG14147 - http://flybase.org/reports/FBgn0036112 protein_coding_gene - - - "BcDNA:RE16005, CG14147" - CG14147 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023042 l(2)46Ea lethal (2) 46Ea http://flybase.org/reports/FBgn0023042 FBgn0019708 gene - - - "P, 24.15, l(2)46CFt, l(2)46Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0037116 Als2 Amyotrophic lateral sclerosis 2 http://flybase.org/reports/FBgn0037116 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence or structural similarity with HGNC:443 guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from direct assay Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence model melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay regulation of Rab protein signal transduction ; GO:0032483 | inferred from sequence model vesicle ; GO:0031982 | inferred from sequence or structural similarity with HGNC:443 "CG7158, Als2, dALS2, ALS2" "IPR000408:Regulator of chromosome condensation, RCC1, IPR003123:VPS9 domain, IPR003409:MORN motif, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR011993:PH domain-like" CG7158 11-Aug-17 DroID_v2017_08 "Drer\als2a, Drer\rcc1, Drer\sergef, Drer\wbscr16, Drer\jph3, Drer\jph2, Drer\morn4, Drer\rpgra, Drer\rccd1, Drer\herc2, Drer\ftr97, Drer\jph1b, Drer\si:ch211-146m13.3, Drer\herc1, Drer\rsph10b, Drer\jph1a, Drer\rpgrb, Drer\rsph1, Drer\als2b, Drer\rcbtb2, Drer\rcbtb1" "Scer\SRM1, Scer\ATS1, Scer\FMP25" Cele\jph-1 "Xtro\als2cl, Xtro\rsph10b, Xtro\rcbtb2, Xtro\morn5, Xtro\als2, Xtro\jph2, Xtro\rsph1, Xtro\jph1, Xtro\rcc1, Xtro\nek9, Xtro\herc1, Xtro\rcbtb1, Xtro\herc2, Xtro\wbscr16" "Mmus\Herc2, Mmus\Rcbtb1, Mmus\Morn1, Mmus\Rcbtb2, Mmus\Rcc1, Mmus\Als2cl, Mmus\Rsph1, Mmus\Als2, Mmus\Jph2, Mmus\Morn4, Mmus\Morn5, Mmus\Gm15800, Mmus\Jph1, Mmus\Jph4, Mmus\Nek9, Mmus\Rccd1, Mmus\Rpgr, Mmus\Sergef, Mmus\Wbscr16, Mmus\Jph3, Mmus\Morn3, Mmus\Herc1" "Hsap\SERGEF, Hsap\HERC1, Hsap\RCBTB1, Hsap\JPH3, Hsap\RPGR, Hsap\MORN3, Hsap\RSPH1, Hsap\MORN4, Hsap\JPH4, Hsap\RCBTB2, Hsap\JPH1, Hsap\ALS2, Hsap\MORN5, Hsap\JPH2, Hsap\RSPH10B, Hsap\HECTD4, Hsap\ALS2CL, Hsap\RCC1L, Hsap\NEK9, Hsap\MORN1, Hsap\HERC2, Hsap\RSPH10B2, Hsap\RCC1, Hsap\RCCD1" "viable,fertile,locomotor behavior defective,progressive,gravitaxis defective,visible,immune response defective" "NMJ bouton,mesothoracic tergum" FBgn0001504 l(1)10Db lethal (1) 10Db http://flybase.org/reports/FBgn0001504 - gene - - - l(1)10Db - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264432 CG43850 - http://flybase.org/reports/FBgn0264432 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43850 - CG43850 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051749 CG31749 - http://flybase.org/reports/FBgn0051749 protein_coding_gene - - - CG31749 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22776 K -0.106948989 -0.13256047 -0.20011671 -0.142590586 -0.545266494 -2.382984487 FBgn0011455 ND-SGDH NADH dehydrogenase (ubiquinone) SGDH subunit http://flybase.org/reports/FBgn0011455 FBgn0036256 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O43674 "response to reactive oxygen species ; GO:0000302 | inferred from mutant phenotype mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O43674 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O43674 mitochondrion ; GO:0005739 | inferred from direct assay "CG9762, l(3)neo18, NISM, ND-SGDH" "IPR019173:NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit" CG9762 11-Aug-17 DroID_v2017_08 Drer\ndufb5 - Cele\C25H3.9 Xtro\ndufb5 Mmus\Ndufb5 Hsap\NDUFB5 "lethal,recessive,stress response defective,aging defective,long lived,female,RU486 conditional,female semi-fertile,viable" FBgn0065835 l(2)SH0338 lethal (2) SH0338 http://flybase.org/reports/FBgn0065835 gene - - - "l(2)SH0338, l(2)SH2 0338" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083274 E(smoDN)2578 Enhancer of smoDN 2578 http://flybase.org/reports/FBgn0083274 gene - - - E(smoDN)2578 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003024 ov oval http://flybase.org/reports/FBgn0003024 - gene - - - ov - - 11-Aug-17 DroID_v2017_08 - - - - - - eye FBgn0267772 CR46103 - http://flybase.org/reports/FBgn0267772 non_protein_coding_gene - - - CR46103 - CR46103 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065937 l(2)SH0123 lethal (2) SH0123 http://flybase.org/reports/FBgn0065937 gene - - - "l(2)SH0123, l(2)SH2 0123" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259421 EP-686 - http://flybase.org/reports/FBgn0259421 gene - - - EP-686 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0266161 CR44867 - http://flybase.org/reports/FBgn0266161 non_protein_coding_gene - - - CR44867 - CR44867 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016638 ER2-1 ER2-1 http://flybase.org/reports/FBgn0016638 - gene - - - ER2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022308 l(1)K87.2 lethal (1) K87.2 http://flybase.org/reports/FBgn0022308 - gene - - - l(1)K87.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051257 CG31257 - http://flybase.org/reports/FBgn0051257 protein_coding_gene - - - CG31257 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025354 Tdc Tyrosine decarboxylase http://flybase.org/reports/FBgn0025354 - gene tyrosine decarboxylase activity ; GO:0004837 | inferred from direct assay behavioral response to cocaine ; GO:0048148 | non-traceable author statement - "TDC, Tdc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266969 CR45420 - http://flybase.org/reports/FBgn0266969 non_protein_coding_gene - - - "CR45420, lincRNA.452" - CR45420 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261641 CG42724 - http://flybase.org/reports/FBgn0261641 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG33097, CG42724, CG15187, CG31367" "IPR011990:Tetratricopeptide-like helical domain, IPR001202:WW domain, IPR002713:FF domain" CG42724 11-Aug-17 DroID_v2017_08 "Drer\tcerg1b, Drer\tcerg1a, Drer\arhgap5" Scer\PRP40 "Cele\ZK1127.6, Cele\tcer-1" "Xtro\tcerg1l, Xtro\tcerg1" "Mmus\Tcerg1l, Mmus\Arhgap5, Mmus\Tcerg1" "Hsap\TCERG1L, Hsap\TCERG1, Hsap\ARHGAP5" """DRSC22275, DRSC12567"" " IE FBgn0262692 Su(VGlut)B8 - http://flybase.org/reports/FBgn0262692 gene - - - "Su(VGlut)B8, B8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030040 CG15347 - http://flybase.org/reports/FBgn0030040 protein_coding_gene - - - CG15347 IPR008472:Domain of unknown function DUF753 CG15347 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051895 tRNA:Phe-GAA-1-3 transfer RNA:Phenylalanine-GAA 1-3 http://flybase.org/reports/FBgn0051895 tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "Phe-tRNA, AE002690.trna5-PheGAA, tRNA:F:GAA:AE002690, CR31895, chr2L.trna14-PheGAA, tRNA-Phe-GAA-1-3, tRNA:Phe-GAA-1-3, tRNA:CR31895, UUC" - CR31895 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030160 CG9691 - http://flybase.org/reports/FBgn0030160 protein_coding_gene - - - "CT27394, BcDNA:RH12290, CG9691" - CG9691 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052251 Claspin Claspin http://flybase.org/reports/FBgn0052251 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic DNA replication checkpoint ; GO:0033314 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG1326, claspin, CG32251, Claspin" IPR024146:Claspin CG32251 11-Aug-17 DroID_v2017_08 - - "Cele\clsp-1, Cele\F49E2.5" Xtro\clspn Mmus\Clspn Hsap\CLSPN "chemical sensitive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,partially lethal - majority die,viable,fertile" FBgn0060560 l(3)S096901a lethal (3) S096901a http://flybase.org/reports/FBgn0060560 gene - - - "0969/01, l(3)S096901a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0061021 l(3)S025255 lethal (3) S025255 http://flybase.org/reports/FBgn0061021 gene - - - "0252/55, l(3)S025255" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0263074 BG01354 - http://flybase.org/reports/FBgn0263074 gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - BG01354 - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive" FBgn0005349 stuck stuck http://flybase.org/reports/FBgn0005349 - gene - copulation ; GO:0007620 | traceable author statement - "sk, stuck" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011474 PR-Set7 PR/SET domain containing protein 7 http://flybase.org/reports/FBgn0011474 FBgn0038222 protein_coding_gene histone methyltransferase activity (H4-K20 specific) ; GO:0042799 | traceable author statement histone methyltransferase activity (H4-K20 specific) ; GO:0042799 | inferred from mutant phenotype histone methylation ; GO:0016571 | inferred from mutant phenotype histone methylation ; GO:0016571 | traceable author statement chromosome condensation ; GO:0030261 | inferred from direct assay inferred from genetic interaction with mei-41 negative regulation of histone acetylation ; GO:0035067 | traceable author statement DNA damage checkpoint ; GO:0000077 | inferred from direct assay histone H4-K20 monomethylation ; GO:0034771 | inferred from mutant phenotype polytene chromosome ; GO:0005700 | inferred from direct assay "PRSET7, PR-Set7, Set8, Set7, PR/SET07, CG3307, dSET8, dSet8, l(3)neo41, pr-Set7, Pr-set-7, PR-SET7, dPR-Set7, pr-set7, SET8, PrSet7" "IPR016858:Histone H4-K20 methyltransferase, IPR001214:SET domain" CG3307 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-23a23.2, Drer\setd8a, Drer\setd8b, Drer\avpr2aa" - Cele\set-1 Xtro\kmt5a Mmus\Kmt5a Hsap\KMT5A "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,suppressor of variegation,dominant,non-suppressor of variegation,non-enhancer of variegation,mitotic cell cycle defective,viable,visible" "eye,wing margin,macrochaeta,melanotic mass,embryonic/larval cuticle,embryonic/larval digestive system,embryonic/larval brain,ventral thoracic disc,wing disc,neuroblast,chromosome,condensed chromosome,embryonic/larval tracheal system,mesothoracic tergum" FBgn0265499 CR44368 - http://flybase.org/reports/FBgn0265499 non_protein_coding_gene - - - CR44368 - CR44368 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044866 MMS-1 MMS-1 http://flybase.org/reports/FBgn0044866 gene - - - MMS-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0034532 CG13436 - http://flybase.org/reports/FBgn0034532 protein_coding_gene - - - CG13436 IPR021897:Cilia- and flagella-associated protein 206 CG13436 11-Aug-17 DroID_v2017_08 Drer\cfap206 - - Xtro\cfap206 Mmus\Cfap206 Hsap\CFAP206 FBgn0267813 CR46138 - http://flybase.org/reports/FBgn0267813 non_protein_coding_gene - - - CR46138 - CR46138 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044078 E(rst)H74 E(rst)H74 http://flybase.org/reports/FBgn0044078 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H74, E(rst)H74" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0053378 5SrRNA:CR33378 5SrRNA:CR33378 http://flybase.org/reports/FBgn0053378 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33378, 5SrRNA:CR33378" - CR33378 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051559 CG31559 - http://flybase.org/reports/FBgn0051559 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR002109 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR002109 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR002109 cellular_component ; GO:0005575 | no biological data available "CG31559, CG15584, CG11461, 31559" "IPR002109:Glutaredoxin, IPR012336:Thioredoxin-like fold" CG31559 11-Aug-17 DroID_v2017_08 "Drer\grxcr1, Drer\si:dkey-109l4.6" - Cele\Y46E12A.3 - "Mmus\Grxcr1, Mmus\Grxcr2" "Hsap\GRXCR1, Hsap\GRXCR2" viable FBgn0267769 CR46100 - http://flybase.org/reports/FBgn0267769 non_protein_coding_gene - - - CR46100 - CR46100 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053199 CG33199 - http://flybase.org/reports/FBgn0053199 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33199 - CG33199 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0035512 Cpr64Ac Cuticular protein 64Ac http://flybase.org/reports/FBgn0035512 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr64Ac, CG15008, DmelCpr64Ac" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG15008 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000120 Arr1 Arrestin 1 http://flybase.org/reports/FBgn0000120 - protein_coding_gene opsin binding ; GO:0002046 | inferred from sequence or structural similarity metarhodopsin inactivation ; GO:0016060 | inferred from genetic interaction with Arr2 endocytosis ; GO:0006897 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from genetic interaction with Arr2 deactivation of rhodopsin mediated signaling ; GO:0016059 | traceable author statement metarhodopsin inactivation ; GO:0016060 | non-traceable author statement photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype desensitization of G-protein coupled receptor protein signaling pathway by arrestin ; GO:0002032 | inferred from mutant phenotype rhabdomere ; GO:0016028 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "FBgn0000120, DmArr1, Arr, arr1, ArrA, PRII, DA, Dmarrestin, 3H10, DS-Ag, CG5711, Arr1, ARR1, Dro.-Arr.I, DAI" "IPR014753:Arrestin, N-terminal, IPR014756:Immunoglobulin E-set, IPR000698:Arrestin, IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR017864:Arrestin, conserved site" CG5711 11-Aug-17 DroID_v2017_08 "Drer\arrb2a, Drer\sagb, Drer\arr3a, Drer\arrb2b, Drer\arrb1, Drer\arr3b, Drer\saga" - Cele\arr-1 "Xtro\arrb1, Xtro\arr3, Xtro\arrb2, Xtro\sag" "Mmus\Arrb1, Mmus\Arrb2, Mmus\Sag, Mmus\Arr3" "Hsap\ARRB1, Hsap\SAG, Hsap\ARR3, Hsap\ARRB2" " adult stage , spermatogenesis && adult stage , adult stage | early , pupal stage | late " " photoreceptor cell &&of ocellus

, testis

, photoreceptor cell &&of retina

" adult stage rhabdomere

"smell perception defective,dominant,increased cell death,viable" "ommatidial cluster & endocytic vesicle,rhabdomere,eye photoreceptor cell" FBgn0005237 l(3)R52 lethal of Roberts 52 http://flybase.org/reports/FBgn0005237 - gene - - - "l(3)B52, l(3)R52" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0005406 l(1)10Dd lethal (1) 10Dd http://flybase.org/reports/FBgn0005406 - gene - - - l(1)10Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031753 CG13999 - http://flybase.org/reports/FBgn0031753 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:26944 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000999503 cilium ; GO:0005929 | inferred from sequence or structural similarity with HGNC:26944 cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN000999503 CG13999 IPR024133:Transmembrane protein 138 CG13999 11-Aug-17 DroID_v2017_08 Drer\tmem138 - Cele\tmem-138 Xtro\tmem138 Mmus\Tmem138 Hsap\TMEM138 viable FBgn0002011 l(2)36Fd lethal (2) 36Fd http://flybase.org/reports/FBgn0002011 - gene - - - "36Fd, Fd, l(2)E51, l(2)36Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011075 l(1)Q28 lethal (1) Q28 http://flybase.org/reports/FBgn0011075 FBgn0010210 gene - - - l(1)Q28 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025770 l(3)89Bu lethal (3) 89Bu http://flybase.org/reports/FBgn0025770 - gene - - - "l(3)M1511, l(3)89Bu" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265978 CR44757 - http://flybase.org/reports/FBgn0265978 non_protein_coding_gene - - - CR44757 - CR44757 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031392 AIF Apoptosis inducing factor http://flybase.org/reports/FBgn0031392 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR016156 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR029324 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR016156, InterPro:IPR023753 DNA binding ; GO:0003677 | NOT inferred from key residues" programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype mitochondrial ATP synthesis coupled electron transport ; GO:0042775 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype mitochondrial intermembrane space ; GO:0005758 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "AIF, aif, CG7263, DmAIF, SD03428p" "IPR023753:FAD/NAD(P)-binding domain, IPR016156:FAD/NAD-linked reductase, dimerisation domain, IPR029324:Mitochondrial apoptosis-inducing factor, C-terminal domain" CG7263 11-Aug-17 DroID_v2017_08 Drer\aifm1 - Cele\wah-1 Xtro\aifm1 Mmus\Aifm1 "Hsap\TXNDC12, Hsap\AIFM1" "immune response defective,dominant,small body,decreased cell death,lethal - all die before end of larval stage,some die during larval stage,lethal,partially,visible,increased cell death,viable" "hemocyte,plasmatocyte,ventral nerve cord,Bolwig organ,eye,ommatidium,eye disc,mesothoracic bristle,trichogen cell" FBgn0036203 Muc68D Mucin 68D http://flybase.org/reports/FBgn0036203 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "anon-WO0153538.48, anon-WO0153538.47, Muc68D, CG6004" IPR002557:Chitin binding domain CG6004 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\W03F11.1, Cele\cbd-1" Xtro\tcof1 - - viable FBgn0067656 sd-11 sd-11 http://flybase.org/reports/FBgn0067656 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0011006 l(3)s1629b lethal (3) s1629b http://flybase.org/reports/FBgn0011006 - gene - - - "l(3)s1629, l(3)s1629b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030675 CG8191 - http://flybase.org/reports/FBgn0030675 protein_coding_gene - - - CG8191 - CG8191 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266516 s-563.1 - http://flybase.org/reports/FBgn0266516 gene - - - s-563.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001816 l(1)P1 lethal (1) P1 http://flybase.org/reports/FBgn0001816 - gene - - - l(1)P1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male,recessive,cold sensitive,viable,female" FBgn0065720 l(2)SH0570 lethal (2) SH0570 http://flybase.org/reports/FBgn0065720 gene - - - l(2)SH0570 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035102 CG7049 - http://flybase.org/reports/FBgn0035102 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN001899580 CG7049 "IPR005532:Sulfatase-modifying factor enzyme, IPR016187:C-type lectin fold" CG7049 11-Aug-17 DroID_v2017_08 "Drer\sumf2, Drer\sumf1" - Cele\F45E1.5 "Xtro\sumf1, Xtro\sumf2" "Mmus\Sumf2, Mmus\Sumf1" "Hsap\SUMF2, Hsap\SUMF1" viable FBgn0033112 Spn42Db Serpin 42Db http://flybase.org/reports/FBgn0033112 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "Spn42Db, CG9454" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG9454 11-Aug-17 DroID_v2017_08 "Drer\serpinh2, Drer\serpine2, Drer\serpinb1l4, Drer\serpina10a, Drer\serpina1l, Drer\serpinb1l1, Drer\zgc:174259, Drer\serpina7, Drer\serpinb1l2, Drer\si:ch1073-416d2.3, Drer\si:ch211-186e20.7, Drer\serpinc1, Drer\serpinh1a, Drer\serpini1, Drer\zgc:173729, Drer\serpinh1b, Drer\serpinb1l3, Drer\serpine3, Drer\serpine1, Drer\serpind1, Drer\serpinb1" - "Cele\srp-6, Cele\srp-1, Cele\srp-8, Cele\srp-3, Cele\srp-7, Cele\srp-2" "Xtro\serpinb6, Xtro\serpine2, Xtro\serpinc1, Xtro\serpine1, Xtro\serpina1, Xtro\serpina10, Xtro\serpinb11, Xtro\serpinb4, Xtro\serpini2, Xtro\serpini1, Xtro\serpina3, Xtro\serpinb1, Xtro\serpinb5, Xtro\serpina3k, Xtro\serpind1, Xtro\serpina3m" "Mmus\Serpini2, Mmus\Serpinb7, Mmus\Serpind1, Mmus\Serpinb3a, Mmus\Serpine1, Mmus\Serpinb1b, Mmus\Serpinb2, Mmus\Serpinb9c, Mmus\Serpinb9g, Mmus\Serpinb11, Mmus\Serpinb12, Mmus\Serpina3c, Mmus\Serpina3a, Mmus\Serpinb9d, Mmus\Serping1, Mmus\Serpina7, Mmus\Serpinb9, Mmus\Serpini1, Mmus\Serpinb6d, Mmus\Serpinb6b, Mmus\Serpina12, Mmus\Serpina1e, Mmus\Serpinb3b, Mmus\Serpina1f, Mmus\Serpinb8, Mmus\Serpinb3c, Mmus\Serpina10, Mmus\Serpinb9f, Mmus\Serpina1c, Mmus\Serpina3f, Mmus\Serpinb6a, Mmus\Serpine2, Mmus\Serpina9, Mmus\Serpina16, Mmus\Gm11397, Mmus\Serpina3i, Mmus\Serpinb1c, Mmus\Serpina1d, Mmus\Serpinb6e, Mmus\Serpinb5, Mmus\Serpinh1, Mmus\Serpina11, Mmus\Serpina3g, Mmus\Serpinb6c, Mmus\Serpina3j, Mmus\Serpina6, Mmus\Serpinb9b, Mmus\Serpinc1, Mmus\Serpina1a, Mmus\Serpinb3d, Mmus\Serpina5, Mmus\Serpinb13, Mmus\Serpina3n, Mmus\Serpina3k, Mmus\Serpinb9e, Mmus\Serpinb10, Mmus\Serpinb1a, Mmus\Serpine3" "Hsap\SERPINB3, Hsap\SERPINA2, Hsap\SERPINA9, Hsap\SERPINI2, Hsap\SERPINA12, Hsap\SERPINB13, Hsap\SERPINB2, Hsap\SERPINB12, Hsap\SERPINA6, Hsap\SERPINA7, Hsap\SERPINB9, Hsap\SERPINB8, Hsap\SERPINC1, Hsap\SERPINB1, Hsap\SERPINA5, Hsap\HMSD, Hsap\SERPINE1, Hsap\SERPIND1, Hsap\SERPINA4, Hsap\SERPINA3, Hsap\SERPINE2, Hsap\SERPINA11, Hsap\SERPINB6, Hsap\SERPINB7, Hsap\SERPINB10, Hsap\SERPINH1, Hsap\SERPINA10, Hsap\SERPINI1, Hsap\SERPINB5, Hsap\SERPINB4, Hsap\SERPINA1, Hsap\SERPINB11, Hsap\SERPING1, Hsap\SERPINE3" viable FBgn0267702 CR46035 - http://flybase.org/reports/FBgn0267702 non_protein_coding_gene - - - CR46035 - CR46035 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267453 CR45803 - http://flybase.org/reports/FBgn0267453 non_protein_coding_gene - - - CR45803 - CR45803 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085733 CR40375 - http://flybase.org/reports/FBgn0085733 non_protein_coding_gene - - - "BcDNA:RE28552, CR40375" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027996 l(3)S125015b lethal (3) S125015b http://flybase.org/reports/FBgn0027996 gene - - - "1250/15, l(3)S125015, l(3)S125015b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "some die during larval stage,lethal,recessive,lethal - all die before end of larval stage" FBgn0031769 CG9135 - http://flybase.org/reports/FBgn0031769 protein_coding_gene - negative regulation of GTPase activity ; GO:0034260 | inferred from sequence or structural similarity with HGNC:30297 microtubule associated complex ; GO:0005875 | inferred from direct assay CG9135 "IPR000408:Regulator of chromosome condensation, RCC1, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG9135 11-Aug-17 DroID_v2017_08 "Drer\sergef, Drer\rcc2" "Scer\FMP25, Scer\ATS1, Scer\HUL4" "Cele\W09G3.7, Cele\glo-4" Xtro\rcc2 "Mmus\Rcc2, Mmus\Sergef" "Hsap\RCC2, Hsap\SERGEF" "viable,fertile,body color defective" mesothoracic tergum FBgn0051075 CG31075 - http://flybase.org/reports/FBgn0051075 protein_coding_gene aldehyde dehydrogenase (NAD) activity ; GO:0004029 | inferred from sequence or structural similarity with UniProtKB:P05091 aldehyde dehydrogenase (NAD) activity ; GO:0004029 | inferred from biological aspect of ancestor with PANTHER:PTN000192421 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016160, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163, InterPro:IPR029510 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:P05091" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P05091 "150697_at, CG6309, CT19744, CG31075, GH20910p" "IPR015590:Aldehyde dehydrogenase domain, IPR016160:Aldehyde dehydrogenase, cysteine active site, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR029510:Aldehyde dehydrogenase, glutamic acid active site" CG31075 11-Aug-17 DroID_v2017_08 "Drer\aldh1l1, Drer\aldh2.1, Drer\aldh16a1, Drer\aldh9a1b, Drer\aldh1a2, Drer\aldh1a3, Drer\aldh8a1, Drer\aldh2.2, Drer\wu:fb14d09, Drer\aldh1l2, Drer\aldh9a1a.1" "Scer\ALD2, Scer\ALD6, Scer\ALD4, Scer\ALD5, Scer\ALD3, Scer\MSC7" "Cele\alh-11, Cele\alh-3, Cele\alh-1, Cele\alh-10, Cele\alh-2" "Xtro\aldh1l2, Xtro\aldh1a1, Xtro\aldh1a3, Xtro\aldh1b1, Xtro\aldh16a1, Xtro\aldh1l1, Xtro\aldh2, Xtro\aldh1a2, Xtro\aldh9a1" "Mmus\Aldh1a7, Mmus\Aldh16a1, Mmus\Aldh1a2, Mmus\Aldh1a1, Mmus\Aldh1b1, Mmus\Aldh9a1, Mmus\Aldh2, Mmus\Aldh1a3, Mmus\Aldh1l1, Mmus\Aldh8a1, Mmus\Aldh1l2" "Hsap\ALDH1A1, Hsap\ALDH9A1, Hsap\ALDH8A1, Hsap\ALDH2, Hsap\ALDH1L2, Hsap\ALDH1A2, Hsap\ALDH1A3, Hsap\ALDH1L1, Hsap\ALDH16A1, Hsap\ALDH1B1" "viable,fertile" FBgn0010649 l(2)08492 lethal (2) 08492 http://flybase.org/reports/FBgn0010649 FBgn0033213 gene - - - l(2)08492 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263341 CR43422 - http://flybase.org/reports/FBgn0263341 non_protein_coding_gene - - - CR43422 - CR43422 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265080 CR44191 - http://flybase.org/reports/FBgn0265080 non_protein_coding_gene - - - CR44191 - CR44191 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069438 EP2190 EP2190 http://flybase.org/reports/FBgn0069438 gene - - - EP2190 - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval salivary gland FBgn0264561 Glg1 Golgi complex-localized glycoprotein 1 http://flybase.org/reports/FBgn0264561 protein_coding_gene fibroblast growth factor binding ; GO:0017134 | inferred from biological aspect of ancestor with PANTHER:PTN000223213 biological_process ; GO:0008150 | no biological data available endomembrane system ; GO:0012505 | inferred from direct assay Golgi medial cisterna ; GO:0005797 | inferred from direct assay Golgi cis cisterna ; GO:0000137 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay Golgi membrane ; GO:0000139 | inferred from direct assay Golgi trans cisterna ; GO:0000138 | inferred from direct assay Golgi medial cisterna ; GO:0005797 | "CG33214, p120-Golgi, dGLG1, Glg1, 120 kDa, 120kDa, GLG1, CG7195, CG7193, CG7190, p120, p120kD, d120kd, 120KD, DG13, d120kD, gp120, d120, 120-kDa" "IPR017873:Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote, IPR001893:Cysteine-rich Golgi apparatus protein 1 repeat" CG33214 11-Aug-17 DroID_v2017_08 "Drer\glg1b, Drer\glg1a" - Cele\F14E5.2 Xtro\glg1 Mmus\Glg1 Hsap\GLG1 FBgn0267285 CR45721 - http://flybase.org/reports/FBgn0267285 non_protein_coding_gene - - - CR45721 - CR45721 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003237 Rev Revolute http://flybase.org/reports/FBgn0003237 - gene - - - "C-K, Rev" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035445 CG12014 - http://flybase.org/reports/FBgn0035445 protein_coding_gene sulfuric ester hydrolase activity ; GO:0008484 | inferred from electronic annotation with InterPro:IPR000917 "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850" - "anon-EST:Posey282, CG12014" "IPR000917:Sulfatase, N-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site" CG12014 11-Aug-17 DroID_v2017_08 "Drer\sgsh, Drer\arsh, Drer\arsg, Drer\si:dkey-174i8.1, Drer\arsia, Drer\LOC563783, Drer\arsk, Drer\arsa, Drer\LOC559800, Drer\LOC101884179, Drer\galns, Drer\ids" - - "Xtro\arsj, Xtro\arsd, Xtro\ids, Xtro\arsh, Xtro\arsa.1, Xtro\arsi, Xtro\sts, Xtro\arsk, Xtro\arsb, Xtro\sgsh" "Mmus\Arsi, Mmus\Arsb, Mmus\Arsk, Mmus\Sgsh, Mmus\Ids, Mmus\Arsg, Mmus\Arsa, Mmus\Arsj, Mmus\Galns" "Hsap\ARSI, Hsap\IDS, Hsap\SGSH, Hsap\ARSK, Hsap\ARSF, Hsap\GALNS, Hsap\ARSA, Hsap\ARSG, Hsap\ARSJ, Hsap\ARSH, Hsap\ARSB, Hsap\STS, Hsap\ARSE, Hsap\ARSD" viable DRSC08222 K 0.844550724 0.405215387 0.116084204 -0.014748685 0.405921189 1.876709539 FBgn0265184 CG44249 - http://flybase.org/reports/FBgn0265184 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 nucleic acid binding ; GO:0003676 | inferred from sequence model with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000467 | inferred from biological aspect of ancestor with PANTHER:PTN000548993 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0005693,GO:0034693" U12 snRNP ; GO:0005693 | inferred from direct assay U11/U12 snRNP ; GO:0034693 | inferred from direct assay U12-type spliceosomal complex ; GO:0005689 | inferred from sequence or structural similarity with HGNC:18666 "CG42257, CG44249, CG30327, CG11478, cg11478, 65K" IPR000504:RNA recognition motif domain CG44249 11-Aug-17 DroID_v2017_08 Drer\eri1 - "Cele\R02D3.8, Cele\crn-4, Cele\eri-1, Cele\M02B7.2" - "Mmus\Eri1, Mmus\Eri3" "Hsap\ERI3, Hsap\ERI1" FBgn0034726 Mes4 Mesoderm-expressed 4 http://flybase.org/reports/FBgn0034726 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype - "MES4, NF-Yc, CG11301, BcDNA:GM21739, Mes4, 11301" "IPR003958:Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072:Histone-fold" CG11301 11-Aug-17 DroID_v2017_08 "Drer\nfyc, Drer\chrac1, Drer\pole4" "Scer\DPB3, Scer\HAP5, Scer\DLS1" "Cele\nfyc-1, Cele\Y53F4B.3" "Xtro\pole4, Xtro\nfyc" "Mmus\Nfyc, Mmus\Chrac1, Mmus\Pole4" "Hsap\NFYC, Hsap\POLE4, Hsap\CHRAC1" " embryonic stage | gastrula , embryonic stage | syncytial blastoderm , embryonic stage | stage 5 " " mesoderm anlage | pair rule

, mesoderm anlage

" "viable,visible,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing disc" FBgn0060812 l(3)S054507b lethal (3) S054507b http://flybase.org/reports/FBgn0060812 gene - - - "0545/07, l(3)S054507b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0022373 Pt-2 Larval protein-2 http://flybase.org/reports/FBgn0022373 - gene - - - Pt-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014186 gyn-3 gyn-3 http://flybase.org/reports/FBgn0014186 - gene - - - gyn-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000152 Axs Abnormal X segregation http://flybase.org/reports/FBgn0000152 "FBtr0074372, FBpp0074146" protein_coding_gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype distributive segregation ; GO:0032837 | inferred from mutant phenotype inferred from genetic interaction with Mps1 inferred from genetic interaction with ncd meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype distributive segregation ; GO:0032837 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity cell cortex ; GO:0005938 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay nuclear outer membrane ; GO:0005640 | inferred from direct assay "axs, CG9703, Axs" IPR007632:Anoctamin CG9703 11-Aug-17 DroID_v2017_08 "Drer\ano10b, Drer\ano10a, Drer\ano8a, Drer\ano8b" Scer\IST2 Cele\anoh-2 "Xtro\ano10, Xtro\ano8" "Mmus\Ano10, Mmus\Ano8" "Hsap\ANO8, Hsap\ANO10" "meiotic cell cycle defective,female,dominant,semidominant,recessive,viable,visible" "meiosis & nuclear chromosome | female,meiosis & nuclear chromosomenos.UTR.THsimVP16,meiosis & nuclear chromosome & spindlenos.UTR.THsimVP16,trichogen cell,mesothoracic tergum" FBgn0002737 M(G6PD) Modifier of Gpdh http://flybase.org/reports/FBgn0002737 - gene - - - "M[Zw], L-a[Zw], M(G6PD)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051604 tRNA:Asp-GTC-1-4 transfer RNA:Aspartic acid-GTC 1-4 http://flybase.org/reports/FBgn0051604 tRNA_gene - - - "tRNA:asp2:29E, tRNA:D2:29E, CR31604, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna31-AspGTC, tRNA:Asp-GTC-1-4, tRNA:CR31604, tRNA-Asp-GTC-1-4, GAC" - CR31604 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067330 2F26 2F26 http://flybase.org/reports/FBgn0067330 gene - - - 2F26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing vein,ectopic,somatic clone,wing,wing vein L3" FBgn0004502 fs(1)gammaa7 female sterile (1) gammaa7 http://flybase.org/reports/FBgn0004502 - gene - - - fs(1)gammaa7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038017 CG4115 - http://flybase.org/reports/FBgn0038017 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - CG4115 "IPR001304:C-type lectin-like, IPR018378:C-type lectin, conserved site, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG4115 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-28d5.12, Drer\si:dkey-28d5.4, Drer\si:ch211-225k7.2, Drer\si:dkey-28d5.10, Drer\si:dkey-28d5.15, Drer\si:dkey-83f18.7, Drer\si:ch211-282j17.11, Drer\si:ch211-282j17.8, Drer\si:ch211-225k7.3, Drer\si:dkey-83f18.10, Drer\si:dkey-88n24.10, Drer\si:ch211-63p21.4, Drer\si:ch211-282j17.7, Drer\si:dkey-28d5.14, Drer\si:dkey-28d5.8" - - - Mmus\Sell "Hsap\CLEC3B, Hsap\CLEC3A, Hsap\SELL" "viable,fertile" FBgn0014024 Rnp4F RNA-binding protein 4F http://flybase.org/reports/FBgn0014024 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR003107 central nervous system development ; GO:0007417 | inferred from mutant phenotype - "4f-rnp, rnp-4f, RNP-4F, 4F-rnp, CG3312, Rnp4F, Rnp-4F" "IPR000504:RNA recognition motif domain, IPR008669:LSM-interacting domain, IPR003107:HAT (Half-A-TPR) repeat, IPR011990:Tetratricopeptide-like helical domain" CG3312 11-Aug-17 DroID_v2017_08 Drer\sart3 "Scer\NOP13, Scer\NOP12, Scer\PRP24" Cele\sart-3 Xtro\sart3 "Mmus\Rbm31y, Mmus\Sart3, Mmus\Srsf7" "Hsap\SART3, Hsap\RBM23" " embryonic stage | stage 4 , embryonic stage | stage 4-16 , embryonic stage | stage 14-16 , embryonic stage , embryonic stage | stage 14 , adult stage , embryonic stage&&larval stage&&adult stage , oogenesis stage | stage >=S10A , oogenesis stage | stage >=S6 , embryonic stage | stage 13 , embryonic stage | stage 10 , pupal stage " " pole cell

, ventral nerve cord commissure

, epidermis

, muscle system | restricted

, ventral nerve cord | dorsal

segmentally repeated , adult head

, embryonic/larval foregut

, oocyte

, embryonic central nervous system

, proctodeum

, nurse cell

, stomodeum

, longitudinal connective

, embryonic/larval hindgut

" "wild-type,lethal,recessive,viable" FBgn0051013 CG31013 - http://flybase.org/reports/FBgn0051013 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG9713, CG31013" "IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG31013 11-Aug-17 DroID_v2017_08 "Drer\p4ha3, Drer\p4ha1b, Drer\p4htm, Drer\zgc:152670, Drer\p4ha2, Drer\p4ha1a, Drer\zgc:158254" - "Cele\phy-2, Cele\Y43F8B.19, Cele\C14E2.4, Cele\phy-3, Cele\phy-4, Cele\dpy-18" "Xtro\p4ha3, Xtro\p4ha2, Xtro\p4ha1" "Mmus\P4ha3, Mmus\P4ha2, Mmus\P4ha1, Mmus\P4htm" "Hsap\P4HA3, Hsap\P4HTM, Hsap\P4HA1, Hsap\P4HA2" viable FBgn0003172 Pw Pointed wing http://flybase.org/reports/FBgn0003172 - gene - - - "Pt, Pw" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" wing FBgn0032727 CG10623 - http://flybase.org/reports/FBgn0032727 protein_coding_gene - - - CG10623 IPR003726:Homocysteine-binding domain CG10623 11-Aug-17 DroID_v2017_08 Drer\zgc:172121 "Scer\YMR321C, Scer\SAM4, Scer\MHT1" "Cele\metr-1, Cele\T13G4.4" "Xtro\mtr, Xtro\MGC75760" "Mmus\Bhmt, Mmus\Bhmt2, Mmus\Mtr" "Hsap\BHMT2, Hsap\MTR, Hsap\BHMT" viable FBgn0011860 tRNA:Gly-GCC-1-2 transfer RNA:Glycine-GCC 1-2 http://flybase.org/reports/FBgn0011860 "FBgn0003776, FBgn0051945, FBgn0060225" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "tRNA:gly3:22BCb, AE002638.trna11-GlyGCC, tRNA:G:GCC:AE002638-b, CR31945, tRNA[Gly-GCC], chr2L.trna4-GlyGCC, tRNA-Gly-GCC-1-2, tRNA:Gly-GCC-1-2, tRNA:G3:22BCb, GGC" - CR31945 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036587 CG4950 - http://flybase.org/reports/FBgn0036587 protein_coding_gene - - - "CT15890, CG4950" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5, IPR003591:Leucine-rich repeat, typical subtype" CG4950 11-Aug-17 DroID_v2017_08 "Drer\tlr8b, Drer\igfals" - Cele\let-4 Xtro\igfals "Mmus\Igfals, Mmus\Tlr3" "Hsap\TLR3, Hsap\IGFALS" viable FBgn0035876 Pex2 Peroxin 2 http://flybase.org/reports/FBgn0035876 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000003746 zinc ion binding ; GO:0008270 | inferred from sequence model peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:9717 peroxisome organization ; GO:0007031 | inferred from mutant phenotype spermatocyte division ; GO:0048137 | inferred from mutant phenotype primary spermatocyte growth ; GO:0007285 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with SGD:S000003746 spermatid development ; GO:0007286 | inferred from mutant phenotype protein import into peroxisome matrix ; GO:0016558 | inferred from mutant phenotype peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:9717 "CG7081, pex2, Pex2, DmelPex2, PEX2" "IPR001841:Zinc finger, RING-type, IPR006845:Pex, N-terminal, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7081 11-Aug-17 DroID_v2017_08 "Drer\si:busm1-163l24.4, Drer\ftr80, Drer\ftr70, Drer\ftr50, Drer\zgc:136302, Drer\ftr29, Drer\ftr54, Drer\ftr97, Drer\ftr43, Drer\pex2, Drer\ftr06, Drer\ftr49, Drer\ftr95, Drer\ftr30, Drer\ftr69, Drer\LOC100330744, Drer\ftr79, Drer\LOC100001589, Drer\ftr15, Drer\ftr03, Drer\ftr27, Drer\ftr33, Drer\ftr35, Drer\ftr66, Drer\LOC100000832, Drer\ftr85, Drer\ftr67, Drer\ftr55" "Scer\PEX2, Scer\PSH1" Cele\prx-2 Xtro\pex2 "Mmus\Rfpl4b, Mmus\Rfpl4, Mmus\Pex2" "Hsap\RFPL4B, Hsap\RFPL3, Hsap\RFPL2, Hsap\RFPL4A, Hsap\RFPL1, Hsap\PEX2, Hsap\RFPL4AL1" "lethal,viable,male sterile,female semi-sterile,developmental rate defective,cytokinesis defective,meiotic cell cycle defective" "spermatid,testis" FBgn0038082 CG5724 - http://flybase.org/reports/FBgn0038082 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG5724 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG5724 11-Aug-17 DroID_v2017_08 "Drer\ugt5f1, Drer\ugt1b5, Drer\ugt5b6, Drer\ugt2a2, Drer\ugt2b5, Drer\ugt2a6, Drer\ugt1b3, Drer\ugt2b6, Drer\ugt5g1, Drer\ugt5d1, Drer\ugt5c3, Drer\ugt2b3, Drer\ugt5b1, Drer\ugt5c2, Drer\ugt5a4, Drer\ugt5c1, Drer\ugt5b3, Drer\ugt5e1, Drer\ugt2b1, Drer\ugt5a2, Drer\ugt1ab, Drer\ugt1b4, Drer\ugt5a5, Drer\zgc:172315, Drer\ugt5b2, Drer\ugt5g2, Drer\ugt5a1, Drer\ugt2a5, Drer\ugt8, Drer\ugt1b7, Drer\ugt1b2" Scer\ATG26 "Cele\ugt-4, Cele\ugt-44, Cele\ugt-51, Cele\F10D2.8, Cele\ugt-53, Cele\ugt-42, Cele\ugt-11, Cele\ugt-26, Cele\ugt-59, Cele\H23N18.4, Cele\ugt-5, Cele\ugt-15, Cele\ugt-12, Cele\ugt-37, Cele\ugt-31, Cele\ugt-2, Cele\ugt-28, Cele\ugt-19, Cele\K04A8.10, Cele\ugt-29, Cele\ugt-22, Cele\ugt-18, Cele\ugt-46, Cele\ugt-33, Cele\ugt-6, Cele\ugt-38, Cele\ugt-14, Cele\ugt-58, Cele\ugt-9, Cele\ugt-23, Cele\ugt-7, Cele\ugt-25, Cele\ugt-43, Cele\ugt-62, Cele\ugt-13, Cele\ugt-34, Cele\ugt-56, Cele\ugt-35, Cele\C03A7.13, Cele\ugt-16, Cele\ugt-17, Cele\ugt-1, Cele\ugt-60, Cele\ugt-50, Cele\ugt-3, Cele\ugt-40, Cele\ugt-61, Cele\ugt-30, Cele\ugt-52, Cele\ugt-55, Cele\ugt-27, Cele\ugt-49, Cele\ugt-45, Cele\ugt-47, Cele\ugt-57, Cele\Y43D4A.2, Cele\ugt-41, Cele\ugt-21, Cele\ugt-39, Cele\ugt-20, Cele\ugt-8, Cele\C03A7.12, Cele\ugt-32, Cele\C55H1.1, Cele\ugt-24, Cele\ugt-10, Cele\ugt-48, Cele\ugt-54, Cele\C23G10.6, Cele\ugt-36" "Xtro\ugt3a2, Xtro\ugt2b4, Xtro\ugt8, Xtro\ugt2a1, Xtro\ugt1a6" "Mmus\Ugt1a6b, Mmus\Ugt2b1, Mmus\Ugt2a1, Mmus\Ugt1a1, Mmus\Ugt1a9, Mmus\Ugt2b5, Mmus\Ugt2b37, Mmus\Ugt3a1, Mmus\Ugt2b36, Mmus\Ugt1a7c, Mmus\Ugt1a2, Mmus\Ugt2b35, Mmus\Ugt1a5, Mmus\Ugt2a3, Mmus\Ugt2b34, Mmus\Ugt2b38, Mmus\Ugt3a2, Mmus\Ugt8a" "Hsap\UGT1A9, Hsap\UGT2B11, Hsap\UGT2B15, Hsap\UGT8, Hsap\UGT2B10, Hsap\UGT2B28, Hsap\UGT1A1, Hsap\UGT1A6, Hsap\UGT2B17, Hsap\UGT1A3, Hsap\UGT1A5, Hsap\UGT2B7, Hsap\UGT2B4, Hsap\UGT1A7, Hsap\UGT1A8, Hsap\UGT1A10, Hsap\UGT2A2, Hsap\UGT1A4, Hsap\UGT2A3, Hsap\UGT3A2, Hsap\UGT3A1" "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell FBgn0001017 fs(3)A8 female sterile (3) A8 http://flybase.org/reports/FBgn0001017 - gene - - - fs(3)A8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0259652 B0462 - http://flybase.org/reports/FBgn0259652 gene - - - B0462 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,antennal segment,arista,proboscis" FBgn0082971 snoRNA:Psi28S-3316b snoRNA:Psi28S-3316b http://flybase.org/reports/FBgn0082971 snoRNA_gene - - - "snoRNA:Psi28S-3316b, Psi28S-3316b, psi28S-3316b, CR34548" - CR34548 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262845 CG43209 - http://flybase.org/reports/FBgn0262845 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43209, DMG4-MB6.chr2R.33.028" - CG43209 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250906 Pgk Phosphoglycerate kinase http://flybase.org/reports/FBgn0250906 protein_coding_gene ATP binding ; GO:0005524 | inferred from sequence or structural similarity with UniProtKB:P00559 phosphoglycerate kinase activity ; GO:0004618 | inferred from sequence or structural similarity with SGD:S000000605 phosphoglycerate kinase activity ; GO:0004618 | inferred from sequence or structural similarity phosphoglycerate kinase activity ; GO:0004618 | inferred from sequence or structural similarity with UniProtKB:P41759 chemical synaptic transmission ; GO:0007268 | inferred from direct assay phosphorylation ; GO:0016310 | inferred from sequence or structural similarity with UniProtKB:P41759 somatic muscle development ; GO:0007525 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype glycolytic process ; GO:0006096 | inferred from sequence or structural similarity with SGD:S000000605 muscle cell cellular homeostasis ; GO:0046716 | inferred from genetic interaction with Dg M band ; GO:0031430 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay "Pgk, CG3127, pgk, l(2)23Ac, 169C9S, PGK, anon-sts18, ESTS:169C9S, l(2)23AB3, pgk1" "IPR015824:Phosphoglycerate kinase, N-terminal, IPR015911:Phosphoglycerate kinase, conserved site, IPR001576:Phosphoglycerate kinase" CG3127 11-Aug-17 DroID_v2017_08 Drer\pgk1 Scer\PGK1 Cele\pgk-1 Xtro\pgk1 "Mmus\Pgk2, Mmus\Pgk1" "Hsap\PGK2, Hsap\PGK1" FBgn0041242 Gr47a Gustatory receptor 47a http://flybase.org/reports/FBgn0041242 protein_coding_gene taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity sensory perception of bitter taste ; GO:0050913 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 "Gr47A1, CG12906, 47A1, 47A.1, GR47A.1, Gr47a, Gr47A" IPR013604:7TM chemoreceptor CG12906 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260505 Pkc53E::Rok - http://flybase.org/reports/FBgn0260505 engineered_fusion_gene - - - "Rok-53E, Pkc53E::rok, Pkc53E::Rok" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020803 ms(3)C131 ms(3)C131 http://flybase.org/reports/FBgn0020803 - gene - - - "3-C131, ms(3)C131" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,male sterile" FBgn0030105 CG15369 - http://flybase.org/reports/FBgn0030105 protein_coding_gene cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from electronic annotation with InterPro:IPR000010 - - CG15369 IPR000010:Cystatin domain CG15369 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0016013 Faa Fumarylacetoacetase http://flybase.org/reports/FBgn0016013 FBgn0035494 protein_coding_gene "fumarylacetoacetase activity ; GO:0004334 | inferred from electronic annotation with InterPro:IPR005959, InterPro:IPR015377" "aromatic amino acid family metabolic process ; GO:0009072 | inferred from electronic annotation with InterPro:IPR005959, InterPro:IPR015377" - "CG14993, l(3)64Al, dfaa, l(3)SH11, Faa" "IPR005959:Fumarylacetoacetase, IPR011234:Fumarylacetoacetase, C-terminal-related, IPR015377:Fumarylacetoacetase, N-terminal" CG14993 11-Aug-17 DroID_v2017_08 Drer\fah - Cele\fah-1 Xtro\fah Mmus\Fah Hsap\FAH "wild-type,lethal,recessive,viable" FBgn0051334 tRNA:Thr-CGT-1-2 transfer RNA:Threonine-CGT 1-2 http://flybase.org/reports/FBgn0051334 tRNA_gene ACG codon-amino acid adaptor activity ; GO:0033440 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033440 cytosol ; GO:0005829 | inferred by curator from GO:0033440 "AE002708.trna24-ThrCGT, tRNA[Thr][[4]], tRNA[Thr][[3]], tRNA:T3:93AB, tRNA:thr4:93A, tRNA:T4:93A, tRNA:T:CGT:AE002708-b, CR31334, tRNA[[Thr]], chr3R.trna30-ThrCGT, tRNA-Thr-CGT-1-2, tRNA:Thr-CGT-1-2, tRNA:CR31334, ACG" - CR31334 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039576 UQCR-14L Ubiquinol-cytochrome c reductase 14 kDa subunit-like http://flybase.org/reports/FBgn0039576 protein_coding_gene ubiquinol-cytochrome-c reductase activity ; GO:0008121 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000246311 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:P14927 "mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:P14927 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 response to reactive oxygen species ; GO:0000302 | inferred from mutant phenotype mitochondrial respiratory chain complex III assembly ; GO:0034551 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:P14927 "CG17856, UCR6, UQCR-14L" IPR003197:Cytochrome b-c1 complex subunit 7 CG17856 11-Aug-17 DroID_v2017_08 Drer\uqcrb Scer\QCR7 Cele\T02H6.11 Xtro\LOC101732809 Mmus\Uqcrb Hsap\UQCRB "lethal - all die before end of larval stage,some die during larval stage,long lived,female,RU486 conditional,female semi-fertile,stress response defective,lethal,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval brain,trichogen cell,mesothoracic tergum,adult heart,RU486 conditional" FBgn0004200 l(3)84Db lethal (3) 84Db http://flybase.org/reports/FBgn0004200 - gene - - - l(3)84Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible" male genitalia FBgn0020649 Hsp64 Heat shock protein 64 http://flybase.net/reports/FBgn0020649.html gene 0009408=response to heat HSP64 11-Aug-17 DroID_v2017_08 FBgn0265369 CR44310 - http://flybase.org/reports/FBgn0265369 non_protein_coding_gene - - - CR44310 - CR44310 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010457 l(2)00064 lethal (2) 00064 http://flybase.org/reports/FBgn0010457 - gene - - - l(2)00064 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0265208 T:SS-Lsp1beta Signal sequence of Lsp1beta http://flybase.org/reports/FBgn0265208 engineered_tag - - - T:SS-Lsp1beta - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035596 CG10677 - http://flybase.org/reports/FBgn0035596 protein_coding_gene - - - "anon-WO0172774.40, CG10677" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038078 CG14391 - http://flybase.org/reports/FBgn0038078 protein_coding_gene - - - "BcDNA:AT22529, CG14391" - CG14391 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263768 CR43685 - http://flybase.org/reports/FBgn0263768 non_protein_coding_gene - - - "CR43685, lincRNA.703" - CR43685 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262307 mir-990 mir-990 stem loop http://flybase.org/reports/FBgn0262307 miRNA_gene - - - "dme-mir-990, mir-990, CR43014, miR-990" - CR43014 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040813 Nplp2 Neuropeptide-like precursor 2 http://flybase.org/reports/FBgn0040813 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | non-traceable author statement humoral immune response ; GO:0006959 | inferred from expression pattern neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "CG11051, NPLP2, BcDNA:RH08410, Nplp2, NPLP 2, nplp2, NEF" - CG11051 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069152 mcl(3)Z3320 mcl(3)Z3320 http://flybase.org/reports/FBgn0069152 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3320 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0015403 l(1)10Bp lethal (1) 10Bp http://flybase.org/reports/FBgn0015403 - gene - - - l(1)10Bp - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262825 CR43196 - http://flybase.org/reports/FBgn0262825 non_protein_coding_gene - - - "CG43196, CR43196" - CR43196 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085675 CG41536 - http://flybase.org/reports/FBgn0085675 protein_coding_gene - - - CG41536 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011805 l(3)rQ303 lethal (3) rQ303 http://flybase.org/reports/FBgn0011805 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(3)rQ303 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,rescuable maternal effect" "embryonic/first instar larval cuticle,amnioserosa" FBgn0065088 snmRNA:641 small non-messenger RNA 641 http://flybase.org/reports/FBgn0065088 non_protein_coding_gene - - - "Dm-641, CR33683, snmRNA:641" - CR33683 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044864 MMS-3 MMS-3 http://flybase.org/reports/FBgn0044864 gene - - - MMS-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0084043 CG41483 - http://flybase.org/reports/FBgn0084043 protein_coding_gene - - - CG41483 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262876 CG43231 - http://flybase.org/reports/FBgn0262876 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43231 - CG43231 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015433 l(1)4Ca lethal (1) 4Ca http://flybase.org/reports/FBgn0015433 - gene - - - l(1)4Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267806 CR46131 - http://flybase.org/reports/FBgn0267806 non_protein_coding_gene - - - CR46131 - CR46131 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027872 rdgBbeta rdgBbeta http://flybase.org/reports/FBgn0027872 - protein_coding_gene phosphatidylinositol transporter activity ; GO:0008526 | inferred from sequence or structural similarity with UniProtKB:Q9UKF7 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001666 signal transduction ; GO:0007165 | inferred from sequence or structural similarity with UniProtKB:Q9UKF7 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9UKF7 "RdgBbeta, RdgB-beta, CG17818, BcDNA.LD14189, DrdgBbeta, BcDNA:LD14189, rdgBbeta" "IPR001666:Phosphatidylinositol transfer protein, IPR023393:START-like domain" CG17818 11-Aug-17 DroID_v2017_08 "Drer\pitpnbl, Drer\pitpnab, Drer\plrdgb, Drer\pitpnaa, Drer\pitpnm3, Drer\zgc:101640, Drer\pitpnc1" - "Cele\Y71G12B.17, Cele\Y54F10AR.1" "Xtro\pitpnm3, Xtro\pitpnc1, Xtro\pitpnb.2, Xtro\pitpnb" "Mmus\Pitpnm2, Mmus\Pitpnb, Mmus\Pitpna, Mmus\Pitpnm3, Mmus\Pitpnm1, Mmus\Pitpnc1" "Hsap\PITPNM2, Hsap\PITPNM1, Hsap\PITPNA, Hsap\PITPNM3, Hsap\PITPNB, Hsap\PITPNC1" viable FBgn0035713 velo veloren http://flybase.org/reports/FBgn0035713 protein_coding_gene receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000687652 SUMO-specific protease activity ; GO:0016929 | inferred from sequence or structural similarity with SGD:S000001293 protein desumoylation ; GO:0016926 | inferred from sequence or structural similarity with SGD:S000001293 negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype dendritic spine morphogenesis ; GO:0060997 | inferred from mutant phenotype central nervous system projection neuron axonogenesis ; GO:0021952 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype toll-like receptor signaling pathway ; GO:0002224 | inferred from biological aspect of ancestor with PANTHER:PTN000687652 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000687652 nucleus ; GO:0005634 | inferred from direct assay "velo, CG10107" "IPR003653:Ulp1 protease family, C-terminal catalytic domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG10107 11-Aug-17 DroID_v2017_08 "Drer\tlr3, Drer\si:dkey-100n23.3, Drer\senp6b, Drer\tlr8a, Drer\tlr9, Drer\LOC100332583, Drer\senp2, Drer\senp7b, Drer\senp6a" Scer\ULP2 "Cele\ulp-2, Cele\tol-1, Cele\ulp-5, Cele\ulp-4" Xtro\senp6 "Mmus\Tlr13, Mmus\Senp7, Mmus\Tlr8, Mmus\Tlr4, Mmus\Cd180, Mmus\Senp6" "Hsap\SENP6, Hsap\SENP7, Hsap\TLR8, Hsap\CD180, Hsap\TLR4" "lethal,neuroanatomy defective,somatic clone,partially lethal - majority die,visible" "adult antennal lobe projection neuron DL1 adPN,somatic clone,antennal lobe glomerulus DL1,dendrite | somatic clone,mesothoracic tergum" DRSC08841 IK -0.236035971 2.018281599 0.418522679 0.756669789 -2.311660769 1.007875968 FBgn0083263 E(smoDN)548 Enhancer of smoDN 548 http://flybase.org/reports/FBgn0083263 gene - - - E(smoDN)548 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035203 CG9149 - http://flybase.org/reports/FBgn0035203 protein_coding_gene acetyl-CoA C-acetyltransferase activity ; GO:0003985 | inferred from biological aspect of ancestor with PANTHER:PTN000432235 acetyl-CoA C-acyltransferase activity ; GO:0003988 | inferred from sequence or structural similarity with HGNC:82 fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000432120 fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:82 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000432235 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:82 "CG9149, ACAT" "IPR002155:Thiolase, IPR016039:Thiolase-like, IPR020615:Thiolase, acyl-enzyme intermediate active site, IPR020616:Thiolase, N-terminal, IPR020610:Thiolase, active site, IPR020613:Thiolase, conserved site, IPR020617:Thiolase, C-terminal" CG9149 11-Aug-17 DroID_v2017_08 "Drer\LOC103910030, Drer\acat2, Drer\acaa2, Drer\acat1, Drer\acaa1, Drer\zgc:123276" Scer\ERG10 "Cele\T02G5.7, Cele\acaa-2, Cele\kat-1" "Xtro\acat1, Xtro\acaa1, Xtro\acaa2, Xtro\acat2" "Mmus\Acaa1b, Mmus\Acat2, Mmus\Acat1, Mmus\Acaa2, Mmus\Acat3, Mmus\Acaa1a" "Hsap\ACAT2, Hsap\ACAT1, Hsap\ACAA1, Hsap\ACAA2" "viable,fertile" DRSC08630 I -0.054740627 1.629565541 -0.063521707 0.303186237 0.075826385 -0.202413332 FBgn0029031 l(2)R89 lethal (2) R89 http://flybase.org/reports/FBgn0029031 gene - - - "R89, l(2)R89" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035397 CG11486 - http://flybase.org/reports/FBgn0035397 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR030844 poly(A)-specific ribonuclease activity ; GO:0004535 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000263578 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 protein kinase activity ; GO:0004672 | NOT inferred from key residues mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR030844 nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from biological aspect of ancestor with PANTHER:PTN000263578 deadenylation-dependent decapping of nuclear-transcribed mRNA ; GO:0000290 | inferred from biological aspect of ancestor with PANTHER:PTN000263578 positive regulation of cytoplasmic mRNA processing body assembly ; GO:0010606 | inferred from biological aspect of ancestor with PANTHER:PTN000263578 protein phosphorylation ; GO:0006468 | NOT inferred from key residues cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000263578 cytoplasm ; GO:0005737 | inferred from direct assay PAN complex ; GO:0031251 | inferred from biological aspect of ancestor with PANTHER:PTN000263578 "PAN3, CG11486" "IPR011009:Protein kinase-like domain, IPR030844:PAB-dependent poly(A)-specific ribonuclease subunit PAN3, IPR032050:Domain of unknown function DUF4797" CG11486 11-Aug-17 DroID_v2017_08 Drer\pan3 Scer\PAN3 Cele\panl-3 Xtro\pan3 Mmus\Pan3 Hsap\PAN3 "viable,fertile,neuroanatomy defective" "intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0265574 Cdc5 Cell division cycle 5 http://flybase.org/reports/FBgn0265574 protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000067606 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:1743 transcription factor activity, RNA polymerase II transcription factor recruiting ; GO:0001135 | inferred from biological aspect of ancestor with PANTHER:PTN000067606 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000067606 sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000067606" "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004826 inferred from sequence or structural similarity with protein_id:AAB61210 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000067606 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000067606" spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000004826 inferred from sequence or structural similarity with protein_id:AAB61210 nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay Prp19 complex ; GO:0000974 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG6905, Cdc5, cef1, cdc5-like, Cdc5Dm, cdc5" "IPR001005:SANT/Myb domain, IPR009057:Homeobox domain-like, IPR017930:Myb domain, IPR021786:Pre-mRNA splicing factor component Cdc5p/Cef1" CG6905 11-Aug-17 DroID_v2017_08 Drer\cdc5l Scer\CEF1 Cele\cdc-5L Xtro\cdc5l "Mmus\Cdc5l, Mmus\Myb" "Hsap\MYB, Hsap\CDC5L" DRSC26879 K -0.429861821 0.152921757 -0.934409282 0.526976763 0.258285986 2.205826794 FBgn0266977 CG45428 - http://flybase.org/reports/FBgn0266977 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45428 - CG45428 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052204 CG32204 - http://flybase.org/reports/FBgn0052204 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32204 IPR031720:Protein of unknown function DUF4728 CG32204 11-Aug-17 DroID_v2017_08 - - - - - - DRSC09574 IE 2.613808098 4.792811906 2.330333898 1.473867504 -0.526476424 1.029875889 FBgn0263937 BG00008 - http://flybase.org/reports/FBgn0263937 gene - - - BG00008 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0261579 CG42689 - http://flybase.org/reports/FBgn0261579 protein_coding_gene - - - CG42689 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039638 dgt6 dim gamma-tubulin 6 http://flybase.org/reports/FBgn0039638 protein_coding_gene - spindle assembly ; GO:0051225 | inferred from electronic annotation with InterPro:IPR026797 regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype HAUS complex ; GO:0070652 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay spindle ; GO:0005819 | colocalizes_with inferred from direct assay "Dgt6, dgt6, CG11881, msd4" "IPR026797:HAUS augmin-like complex subunit 6, IPR028163:HAUS augmin-like complex subunit 6, N-terminal" CG11881 11-Aug-17 DroID_v2017_08 Drer\haus6 - - Xtro\haus6 Mmus\Haus6 Hsap\HAUS6 viable FBgn0003958 upt upturned bristles http://flybase.org/reports/FBgn0003958 - gene - - - upt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "dorsocentral bristle,anterior scutellar bristle" FBgn0259785 pzg putzig http://flybase.org/reports/FBgn0259785 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q86BS3,UniProtKB:Q9VCH5,UniProtKB:Q9VGA4" neurogenesis ; GO:0022008 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with N negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with H positive regulation of mitotic cell cycle ; GO:0045931 | inferred from mutant phenotype polytene chromosome interband ; GO:0005705 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay NURF complex ; GO:0016589 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG7752, Z4, pzg, p160, Pzg, z4, Q9VP57_DROME, Pzg/Z4" IPR013087:Zinc finger C2H2-type CG7752 11-Aug-17 DroID_v2017_08 "Drer\LOC563292, Drer\zfx, Drer\znf711" - "Cele\C04F5.9, Cele\ztf-29, Cele\Y48G8AL.10, Cele\zag-1" "Xtro\zfx, Xtro\znf711, Xtro\znf639" "Mmus\Zfy2, Mmus\Zfp639, Mmus\Zfx, Mmus\Zfp711, Mmus\Zfy1" "Hsap\ZNF639, Hsap\ZNF711, Hsap\ZFX, Hsap\ZFY" DRSC11848 I -1.050601956 -2.025602304 -1.251805105 -1.494414055 0.619320857 0.60379245 FBgn0028172 l(3)S027302b lethal (3) S027302b http://flybase.org/reports/FBgn0028172 gene - - - "0273/02, l(3)S027302, l(3)S027302b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261399 Pp1-Y1 "Protein phosphatase 1, Y-linked 1" http://flybase.org/reports/FBgn0261399 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with MGI:MGI:104871 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with MGI:MGI:104871 protein phosphatase type 1 complex ; GO:0000164 | colocalizes_with inferred from direct assay "CG41534, Pp1-Y1, DmPp1-Y1, Pp1Y1" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like, IPR031675:Serine-threonine protein phosphatase, N-terminal" CG41534 11-Aug-17 DroID_v2017_08 "Drer\ppp1cbl, Drer\ppp1cb" "Scer\PPQ1, Scer\PPZ2, Scer\GLC7, Scer\PPZ1" "Cele\R13A5.11, Cele\F58G1.3, Cele\T25B9.2, Cele\Y71G12B.30, Cele\F52H3.6, Cele\ZK938.1, Cele\pph-1, Cele\F23B12.1, Cele\F22D6.9, Cele\C30A5.4, Cele\C34D4.2, Cele\gsp-1, Cele\C06A1.3, Cele\Y69E1A.4" "Xtro\ppp1cb, Xtro\ppp1ca" Mmus\Ppp1cb Hsap\PPP1CB FBgn0261059 Sfp78E Seminal fluid protein 78E http://flybase.org/reports/FBgn0261059 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp78E, CG42607" - CG42607 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035751 CG14829 - http://flybase.org/reports/FBgn0035751 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14829 IPR006631:Protein of unknown function DM4/12 CG14829 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082350 HM388 HM388 http://flybase.org/reports/FBgn0082350 gene - - - HM388 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266214 CR44909 - http://flybase.org/reports/FBgn0266214 non_protein_coding_gene - - - CR44909 - CR44909 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267267 CR45703 - http://flybase.org/reports/FBgn0267267 non_protein_coding_gene - - - CR45703 - CR45703 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022082 l(2)k07525 lethal (2) k07525 http://flybase.org/reports/FBgn0022082 - gene - - - l(2)k07525 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0012051 CalpA Calpain-A http://flybase.org/reports/FBgn0012051 FBgn0034444 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | inferred from direct assay calcium ion binding ; GO:0005509 | non-traceable author statement dorsal/ventral pattern formation ; GO:0009953 | inferred from direct assay protein autoprocessing ; GO:0016540 | traceable author statement larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype protein autoprocessing ; GO:0016540 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from direct assay BMP signaling pathway involved in spinal cord dorsal/ventral patterning ; GO:0021919 | inferred from direct assay neuron remodeling ; GO:0016322 | inferred from mutant phenotype inferred from genetic interaction with Ca-β cuticle development ; GO:0042335 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000021568 intracellular ; GO:0005622 | inferred from direct assay actin cytoskeleton ; GO:0015629 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "CG7563, EST C, CG18152, CalpA, calpA" "IPR000169:Cysteine peptidase, cysteine active site, IPR001300:Peptidase C2, calpain, catalytic domain, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR033883:Calpain subdomain III, IPR022682:Peptidase C2, calpain, large subunit, domain III, IPR022683:Peptidase C2, calpain, domain III, IPR022684:Peptidase C2, calpain family" CG7563 11-Aug-17 DroID_v2017_08 "Drer\capn1a, Drer\capn15, Drer\capn12, Drer\capn2b, Drer\zgc:162184, Drer\zgc:85932, Drer\zgc:136872, Drer\si:ch211-202f3.3, Drer\capn3a, Drer\zgc:92480, Drer\capn3b, Drer\capn5a, Drer\si:dkey-19b23.13, Drer\adgb, Drer\capn5b, Drer\capn9, Drer\capn8, Drer\capn10, Drer\capn1b, Drer\si:dkeyp-50d11.2, Drer\capn2l, Drer\si:ch211-202f3.4, Drer\zgc:55262, Drer\capn2a" "Scer\PEF1, Scer\RIM13" "Cele\clp-7, Cele\clp-1, Cele\clp-3, Cele\clp-6, Cele\clp-4" "Xtro\capn7, Xtro\LOC100494922, Xtro\capn8, Xtro\capn15, Xtro\capn10, Xtro\capn1, Xtro\capn3, Xtro\capn13, Xtro\capn9, Xtro\LOC100497805, Xtro\capn2.2, Xtro\capn6" "Mmus\Capn7, Mmus\Capn2, Mmus\Capn11, Mmus\Capn9, Mmus\Capn1, Mmus\Capn6, Mmus\Capn13, Mmus\Capn5, Mmus\Capn8, Mmus\Capn15, Mmus\Capn3, Mmus\Adgb, Mmus\Capn10, Mmus\Capn12" "Hsap\CAPN5, Hsap\CAPN14, Hsap\CAPN10, Hsap\CAPN2, Hsap\CAPN3, Hsap\CAPN13, Hsap\ADGB, Hsap\CAPN9, Hsap\CAPN8, Hsap\CAPN6, Hsap\CAPN12, Hsap\CAPN1, Hsap\CAPN15, Hsap\CAPN7, Hsap\CAPN11" " adult stage , embryonic stage -- adult stage , oogenesis stage && larval stage , larval stage " " adult proventriculus

, ovary

, adult midgut | restricted

, adult central nervous system

, embryonic/larval hemocoel

" " embryonic stage | cycle 8-13 , adult stage , embryonic stage | early , larval stage " "

, adult midgut | restricted

, tritocerebrum | restricted

, protocerebrum | restricted

,

anterior , pole bud

, adult central nervous system | restricted

, embryonic/larval fat body

,

posterior " "viable,long lived,immune response defective" FBgn0016642 ER2-7A ER2-7A http://flybase.org/reports/FBgn0016642 - gene - - - ER2-7A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067317 Cby Chibby http://flybase.org/reports/FBgn0067317 protein_coding_gene - non-motile cilium assembly ; GO:1905515 | inferred from genetic interaction with dila segment polarity determination ; GO:0007367 | inferred from genetic interaction with arm sperm axoneme assembly ; GO:0007288 | inferred from genetic interaction with dila protein localization to ciliary transition zone ; GO:1904491 | inferred from genetic interaction with dila spermatid development ; GO:0007286 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype axoneme assembly ; GO:0035082 | inferred from mutant phenotype ciliary basal body docking ; GO:0097711 | inferred from genetic interaction with dila ciliary transition zone assembly ; GO:1905349 | inferred from genetic interaction with dila negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype inferred from genetic interaction with wg centriole ; GO:0005814 | colocalizes_with inferred from direct assay ciliary transition zone ; GO:0035869 | inferred from direct assay ciliary basal body ; GO:0036064 | inferred from direct assay "CG13415, Cby, cby" IPR028118:Chibby family CG13415 11-Aug-17 DroID_v2017_08 Drer\cby1 - - Xtro\cby1 "Mmus\Spert, Mmus\Cby1" "Hsap\CBY3, Hsap\CBY1, Hsap\SPERT" "viable,male semi-fertile,gravitaxis defective,auditory perception defective,small body" "denticle,ectopic,embryonic head,Johnston organ,chordotonal organ,scolopidial cilium,microtubule,cilium axoneme,ciliary basal body,ciliary transition zone,ciliary membrane,spermatid,Nebenkern derivative,embryonic/first instar larval cuticle,midgut constriction 1" FBgn0065520 l(2)SH1134 lethal (2) SH1134 http://flybase.org/reports/FBgn0065520 gene - - - "l(2)SH1134, l(2)SH2 1134" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264703 CR43972 - http://flybase.org/reports/FBgn0264703 pseudogene_attribute - - - CR43972 - CR43972 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039881 CG1971 - http://flybase.org/reports/FBgn0039881 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG1971 - CG1971 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC28390 K 0.481974853 0.562227074 0.391371725 -0.034819512 1.989987787 -0.66991197 FBgn0033715 CG8490 - http://flybase.org/reports/FBgn0033715 protein_coding_gene - - - CG8490 - CG8490 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025333 anon-85Aa anon-85Aa http://flybase.org/reports/FBgn0025333 - gene - - - anon-85Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013141 sev::Dvir\sev sev::Dvir\sev http://flybase.org/reports/FBgn0013141 - engineered_fusion_gene - - - sev::Dvir\sev - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022712 406 406 http://flybase.org/reports/FBgn0022712 - gene - - - 406 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002714 mei-S282 meiotic from via Salaria 282 http://flybase.org/reports/FBgn0002714 - gene molecular_function ; GO:0003674 | no biological data available female meiotic division ; GO:0007143 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mei-282, mei-S282" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,female,recessive,mitotic cell cycle defective" FBgn0038149 GILT1 Gamma-interferon-inducible lysosomal thiol reductase 1 http://flybase.org/reports/FBgn0038149 protein_coding_gene disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence model with Pfam:PF03227 positive regulation of defense response to bacterium ; GO:1900426 | inferred from mutant phenotype oxidation-reduction process ; GO:0055114 | inferred from sequence model with Pfam:PF03227 plasma membrane ; GO:0005886 | inferred from direct assay "CG9796, GILT, GILT1" IPR004911:Gamma interferon inducible lysosomal thiol reductase GILT CG9796 11-Aug-17 DroID_v2017_08 "Drer\ifi30, Drer\si:dkey-197i20.6" - "Cele\ZK669.3, Cele\W04A4.3, Cele\pqn-48, Cele\C02D5.2, Cele\ZK669.2, Cele\Y18D10A.2, Cele\R07E5.4, Cele\F37H8.5" Xtro\ifi30 Mmus\Ifi30 Hsap\IFI30 "immune response defective,viable,fertile,body color defective" mesothoracic tergum DRSC16565 K -0.549458203 0.456991065 0.055643934 0.389739385 0.080759842 1.747843653 FBgn0082927 snoRNA:Me28S-G3255b snoRNA:Me28S-G3255b http://flybase.org/reports/FBgn0082927 snoRNA_gene - - - "snoRNA:Me28S-G3255b, Me28S-Gm3255b, CR34529, DmSnR48b" - CR34529 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260055 2L3301 - http://flybase.org/reports/FBgn0260055 gene - - - 2L3301 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0263325 CR43406 - http://flybase.org/reports/FBgn0263325 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43406, CG43406, mdcds_4120, mdcds_4123" - CR43406 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028037 l(3)S100604 lethal (3) S100604 http://flybase.org/reports/FBgn0028037 gene - - - "1006/04, l(3)S100604" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264989 CG44140 - http://flybase.org/reports/FBgn0264989 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44140 - CG44140 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000335 cmp crumpled http://flybase.org/reports/FBgn0000335 - gene - - - "cm, cmp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,dorsal row,ventral row,medial triple row,leg,macrochaeta,scutellar bristle,arista" FBgn0050085 Rif1 Rap1 interacting factor 1 http://flybase.org/reports/FBgn0050085 protein_coding_gene - maintenance of chromatin silencing at telomere ; GO:0035392 | NOT inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | NOT inferred from direct assay inferred from mutant phenotype regulation of DNA-dependent DNA replication initiation ; GO:0030174 | inferred from mutant phenotype "chromosome ; GO:0005694 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear heterochromatin ; GO:0005720 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay" "BcDNA:LD22218, Rif1, dRif1, CG30085" "IPR016024:Armadillo-type fold, IPR028566:Telomere-associated protein Rif1, IPR011989:Armadillo-like helical, IPR022031:Telomere-associated protein Rif1, N-terminal" CG30085 11-Aug-17 DroID_v2017_08 Drer\rif1 Scer\RIF1 "Cele\F19H6.3, Cele\F11E6.7" Xtro\rif1 Mmus\Rif1 Hsap\RIF1 viable FBgn0043366 EP2002b EP2002b http://flybase.org/reports/FBgn0043366 gene - - - EP2002b - - 11-Aug-17 DroID_v2017_08 - - - - - - visible tormogen cell FBgn0011200 l(1)304-71 lethal (1) 304-71 http://flybase.org/reports/FBgn0011200 FBgn0010203 gene - - - "304-71, l(1)304-71" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065845 l(2)SH0319 lethal (2) SH0319 http://flybase.org/reports/FBgn0065845 gene - - - "l(2)SH0319, l(2)SH2 0319" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003391 shg shotgun http://flybase.org/reports/FBgn0003391 "FBgn0010661, FBgn0012050" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with N myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A protein homodimerization activity ; GO:0042803 | inferred from physical interaction with shg receptor activity ; GO:0004872 | inferred from sequence or structural similarity calcium ion binding ; GO:0005509 | inferred from direct assay beta-catenin binding ; GO:0008013 | non-traceable author statement cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity "morphogenesis of an epithelium=0002009 | <> segment specification=0007379 |...<> germarium-derived female germ-line cyst encapsulation=0030708 | traceable author statement <> cell adhesion=0007155 |...<> homophilic cell adhesion via plasma membrane adhesion molecules=0007156 |... direct assay <> asymmetric cell division=0008356 |...<> nervous system development=0007399 |...<> wound healing=0042060 |...<> gastrulation involving germ band extension=0010004 |...<> gonad development=0008406 | traceable author statement <> border follicle cell migration=0007298 |...<> calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules=0016339 |... sequence or structural similarity <> branch fusion, open tracheal system=0035147 | traceable author statement <> head involution=0008258 |...<> gonad morphogenesis=0035262 |...inferred from genetic interaction with foi <> pole cell migration=0007280 | traceable author statement <> oocyte localization involved in germarium-derived egg chamber formation=0030720 | traceable author statement <> border follicle cell migration=0007298 | traceable author statement <> compound eye morphogenesis=0001745 |... genetic interaction with p120ctn <> determination of digestive tract left/right asymmetry=0071907 |...<> ventral furrow formation=0007370 |...<> outflow tract morphogenesis=0003151 |...<> cell-cell adhesion mediated by cadherin=0044331 |... direct assay <> germ-line stem cell division=0042078 | traceable author statement <> ommatidial rotation=0016318 |...<> female germ-line stem cell population maintenance=0036099 |...<> germ cell development=0007281 |...<> apical protein localization=0045176 |...<> cell competition in a multicellular organism=0035212 |...<> brain development=0007420 |...<> establishment or maintenance of cell polarity=0007163 | <> oocyte anterior/posterior axis specification=0007314 | <> gonadal mesoderm development=0007506 |...<> axonogenesis=0007409 |...<> heart development=0007507 |...<> homophilic cell adhesion via plasma membrane adhesion molecules=0007156 |... sequence or structural similarity <> asymmetric protein localization=0008105 |...<> salivary gland morphogenesis=0007435 |... genetic interaction with Rac1 <> hemocyte migration=0035099 |... genetic interaction with RhoL <> germ cell migration=0008354 |...<> somatic stem cell division=0048103 | traceable author statement <> cuticle development=0042335 |... genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 <> oogenesis=0048477 |...<> calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules=0016339 |... direct assay <> single organismal cell-cell adhesion=0016337 |...<> zonula adherens assembly=0045186 |...<> optic lobe placode development=0001748 |...<> maintenance of epithelial integrity, open tracheal system=0035160 |...<> cell projection assembly=0030031 |...<> cell morphogenesis=0000902 |...<> axon guidance=0007411 | <> defense response to fungus=0050832 |...<> male germline stem cell symmetric division=0098730 |...<> open tracheal system development=0007424 | traceable author statement <> somatic stem cell population maintenance=0035019 | traceable author statement <> branch fusion, open tracheal system=0035147 |...<> somatic stem cell population maintenance=0035019 |...<> ovarian follicle cell migration=0007297 | traceable author statement <> heart development=0007507 | traceable author statement <> compound eye morphogenesis=0001745 |...<> oogenesis=0048477 | traceable author statement <> gonad development=0008406 |...<> open tracheal system development=0007424 |...<> morphogenesis of an epithelium=0002009 | traceable author statement <> morphogenesis of a polarized epithelium=0001738 |... mutant phenotype" zonula adherens ; GO:0005915 | non-traceable author statement filopodium ; GO:0030175 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity adherens junction ; GO:0005912 | non-traceable author statement cell-cell adherens junction ; GO:0005913 | traceable author statement cell-cell adherens junction ; GO:0005913 | inferred from direct assay plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay spot adherens junction ; GO:0005914 | inferred from direct assay spot adherens junction ; GO:0005914 | non-traceable author statement catenin complex ; GO:0016342 | inferred from direct assay apical junction complex ; GO:0043296 | inferred from direct assay adherens junction ; GO:0005912 | "DE-Cad, shg, E-cad, DE-cad, E-Cad, Ecad, DCAD2, DE-cadherin, E-cadherin, Cad, Shg, CT12481, shg/DE-Cad, DE, DE[cyto], DE-CAD, CADH, DCad, DEC, l(2)k10220, l(2)k03401, DECad, D-cad, gp150, l(2)10469, CadE, CG3722, DEcad, De-Cad, DE-Cadherin, e-cad, ECad, N-cad, cadh, DE-cadh, ECadh, DE Cad, DE-Cad2, E-CAD, E-Cadherin, ECAD, cad, dEcad, DE-CAD2, Cadh, DCAD, ECad2, DCad2, com5, DECadh, de-cad, D-CAD2, D E-cad, DE Cadh, DE-Cadh, E-Ca, DECAD, ecad" "IPR015919:Cadherin-like, IPR000233:Cadherin, cytoplasmic domain, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR002126:Cadherin, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR027397:Catenin binding domain, IPR020894:Cadherin conserved site" CG3722 11-Aug-17 DroID_v2017_08 "Drer\LOC100536716, Drer\fat1b, Drer\cdh8, Drer\cdh23, Drer\cdh15, Drer\cdh19, Drer\fat3a, Drer\cdh12a, Drer\fat2, Drer\LOC567936, Drer\LOC570372, Drer\cdh2, Drer\cdh31, Drer\si:dkey-22o22.2, Drer\pcdh15b, Drer\cdh6, Drer\LOC100534755, Drer\dchs1b, Drer\si:dkey-30c15.12, Drer\fat1a, Drer\cdh10a, Drer\pcdh15a, Drer\cdh11, Drer\LOC100329245, Drer\cdh18a, Drer\dchs1a, Drer\si:ch211-186j3.6, Drer\cdh18b, Drer\cdh4, Drer\cdh7, Drer\cdh1, Drer\cdh5" - Cele\hmr-1 "Xtro\fat1, Xtro\dchs2, Xtro\fat4" "Mmus\Cdh12, Mmus\Fat1, Mmus\Cdh19, Mmus\Dsg1c, Mmus\Fat2, Mmus\Cdh5, Mmus\Cdh15, Mmus\Cdh11, Mmus\Fat3, Mmus\Dsg1a, Mmus\Cdh7, Mmus\Cdh24, Mmus\Cdh1, Mmus\Cdh4, Mmus\Cdh23, Mmus\Cdh3, Mmus\Cdh18, Mmus\Cdh22, Mmus\Cdh10, Mmus\Cdh20, Mmus\Dsg1b, Mmus\Cdh9, Mmus\Cdh8, Mmus\Cdh6, Mmus\Cdh2, Mmus\Dchs1, Mmus\Pcdh15" "Hsap\PCDH15, Hsap\CDH8, Hsap\FAT2, Hsap\CDH10, Hsap\FAT1, Hsap\FAT3, Hsap\CDH11, Hsap\CDH22, Hsap\CDH9, Hsap\DCHS1, Hsap\CDH5, Hsap\CDH12, Hsap\CDH15, Hsap\CDH3, Hsap\CDH23, Hsap\DCHS2, Hsap\CDH7, Hsap\CDH24, Hsap\CDH6, Hsap\CDH19, Hsap\DSG1, Hsap\DLK2, Hsap\CDH1, Hsap\CDH2, Hsap\CDH20, Hsap\FAT4, Hsap\CDH4, Hsap\CDH18" " embryonic stage , embryonic stage | stage >=12 , embryonic stage | stage 17 , embryonic stage | stage 8 , egg stage | unfertilized egg " " amnioserosa

, midgut primordium

, gonadal sheath

, embryonic/larval tracheal system

, embryonic/larval dorsal vessel

, dorsal ectoderm

, epithelial cell

, embryonic/larval hindgut

, embryonic/larval salivary gland

, embryonic epidermis

, ventral neurogenic region

, unfertilized egg

, embryonic/larval foregut

, Malpighian tubule

, subperineurial glial cell

" " embryonic stage , embryonic stage | cellular blastoderm , embryonic stage | stage 17 , embryonic stage | stage 13-14 " " Malpighian tubule

, epidermis

, embryonic/larval hindgut

, gonad | restricted & anterior

, embryonic/larval salivary gland

, ectoderm

, embryonic/larval tracheal system

, gonad | restricted

" "cell polarity defective,immune response defective,dominant,lethal,viable,recessive,cell migration defective,cell non-autonomous,somatic clone,wound healing defective,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,size defective,germline clone,cell adhesion defective,cell shape defective,increased cell death,visible,mitotic cell cycle defective,wild-type,lethal - all die before end of pupal stage,some die during pupal stage" "hemocyte,embryonic head,embryonic ventral epidermis,cell-cell adherens junction | embryonic stage, with shgR69,ventral furrow,border follicle cell,somatic clone,embryonic/first instar larval cuticle,oocyte,embryonic head & embryonic/first instar larval cuticle,ventral,egg chamber,epithelial cell,cardioblast,cardioblast & adherens junction,sensory mother cell,ommatidial precursor cluster,cell non-autonomous,organism | embryonic stage,ommatidium,wing,Malpighian tubule,tracheal branch primordium,embryonic/larval dorsal trunk,follicle stem cell,gonad,embryonic/larval hindgut,female germline stem cell,germline clone,cone cell,primary pigment cell,centripetally migrating follicle cell,male germline stem cell,embryonic/larval trachea,imaginal disc,cell-cell adherens junction | embryonic stage, with shgDE‘î734-1316.Ubi.TAvicGFP-EGFP,germinal proliferation center hub,germline cell,maternal effect,embryonic epidermis,ovary,egg,embryonic/larval dorsal vessel,follicle cell,embryonic head epidermis,embryonic/first instar larval cuticle & embryonic head,presumptive embryonic/larval tracheal system,endoderm,neurogenic region,presumptive embryonic/larval peripheral nervous system,stomatogastric nervous system,visual primordium,gonadal sheath proper primordium,fat body/gonad primordium,male,cell | cell autonomous | somatic clone,embryonic/larval tracheal system,embryonic epidermis & embryonic head,head,lateral,tracheal system,embryonic optic lobe primordium,embryonic optic lobe,tracheolar cell,embryonic trachea & cortical actin cytoskeleton,Bolwig organ,posterior spiracle primordium,presumptive embryonic/larval nervous system,adherens junction | embryonic stage,embryonic/larval dorsal branch,border follicle cell & filopodium | somatic clone | cell non-autonomous,border follicle cell & filopodium | somatic clone,cell | apical | cell autonomous | somatic clone,nurse cell,nurse cell ring canal,wing disc,apical plasma membrane & cell & dorsal mesothoracic disc & third instar larva | somatic clone,cyst progenitor cell,microtubule & adherens junctionbtl.PS,morphogenetic furrow,nucleus | blastoderm stagemat.‘±Tub67C.THsimVP16,plasma membrane | blastoderm stagemat.‘±Tub67C.THsimVP16,spindlemat.‘±Tub67C.THsimVP16,neuroblast,gastrula embryo,zonula adherens | embryonic stagemat.‘±Tub67C.THsimVP16,embryonic/larval brain,anterior protocerebral neuromere,neuropil associated CNS glial cell,cortex associated CNS glial cell,neuropil,ectopic,fascicle,lamina cortex & satellite glial cellnrv2.PS,embryonic/larval cell body glial cell,wing margin,denticle & embryonic epidermis | somatic clone‘±Tub84B.PP,denticle,posterior compartment,embryonic/larval salivary gland,histoblast,histoblast nest,male genitalia,heat sensitive,wing hair,wing blade,flight muscle" DRSC27751 K 0.330875855 0.250418305 0.002929325 0.044303028 1.557147448 -0.831267202 FBgn0003060 CG9757 - http://flybase.org/reports/FBgn0003060 - protein_coding_gene - - - "GCR 20, GCR-20, pen50DE, anon-Pen50DE, Pen50DE, GCR20, CG9757" - CG9757 11-Aug-17 DroID_v2017_08 - - Cele\F12A10.7 - - - FBgn0250741 l(3)S044324 lethal (3) S044324 http://flybase.org/reports/FBgn0250741 gene - - - "l(3)S044324, l(3)s044324" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052313 CG32313 - http://flybase.org/reports/FBgn0052313 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - extracellular region ; GO:0005576 | inferred from sequence model CG32313 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain" CG32313 11-Aug-17 DroID_v2017_08 "Drer\glipr2l, Drer\glipr2, Drer\crispld2, Drer\pi15b, Drer\r3hdml, Drer\crispld1a, Drer\crispld1b, Drer\glipr1b, Drer\im:7150988, Drer\LOC101883528, Drer\pi15a, Drer\LOC100536500" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\D2062.1, Cele\scl-19, Cele\C07A4.2, Cele\vap-2" "Xtro\r3hdml, Xtro\MGC108118, Xtro\glipr2, Xtro\crispld2, Xtro\crisp2, Xtro\crisp3, Xtro\crisp1" "Mmus\Pi16, Mmus\R3hdml, Mmus\Glipr1l1, Mmus\Glipr1, Mmus\Crisp1, Mmus\Pi15, Mmus\Glipr2, Mmus\Clec18a, Mmus\Crisp2, Mmus\Crisp4, Mmus\Glipr1l2, Mmus\Crispld2, Mmus\Crisp3, Mmus\Crispld1" "Hsap\CRISPLD1, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\CRISPLD2, Hsap\PI15, Hsap\CLEC18A, Hsap\R3HDML, Hsap\CRISP2, Hsap\GLIPR2, Hsap\GLIPR1, Hsap\PI16, Hsap\CLEC18B" viable FBgn0001201 Hiv Haploinviable http://flybase.org/reports/FBgn0001201 - gene - - - "L(1)7C, Hiv" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031610 CG15436 - http://flybase.org/reports/FBgn0031610 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG15436 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15436 11-Aug-17 DroID_v2017_08 "Drer\LOC100535458, Drer\LOC100148466, Drer\si:dkey-201g16.1, Drer\LOC101882721, Drer\si:dkey-262g12.7, Drer\zgc:163077, Drer\LOC101883594, Drer\zgc:174275, Drer\LOC560148, Drer\zgc:66483, Drer\si:ch73-138e16.8" Scer\PZF1 "Cele\Y5F2A.4, Cele\lsy-2, Cele\klu-2, Cele\ztf-14, Cele\snai-1, Cele\blmp-1, Cele\lsl-1, Cele\Y55F3AM.14, Cele\ehn-3, Cele\M03D4.4, Cele\hinf-1, Cele\zfp-2, Cele\eor-1, Cele\ZK177.3" "Xtro\zfp1, Xtro\LOC100495617" "Mmus\Zfp1, Mmus\Zfp637, Mmus\Zfp771, Mmus\Zfp664, Mmus\Zfp935, Mmus\Zfp146" "Hsap\ZNF510, Hsap\ZFP1, Hsap\ZNF32, Hsap\ZNF560, Hsap\ZNF577" "viable,fertile" DRSC29550 K 0.87064539 0.118036584 0.37362367 -0.15678215 -0.508593914 -3.87609668 FBgn0028919 CG16865 - http://flybase.org/reports/FBgn0028919 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "BG:DS00941.3, CG16865" IPR029704:UPF0428 family CG16865 11-Aug-17 DroID_v2017_08 Drer\zgc:103697 - Cele\Y66D12A.8 Xtro\cxorf56 Mmus\C330007P06Rik Hsap\CXorf56 "viable,fertile" FBgn0045038 Proc Proctolin http://flybase.org/reports/FBgn0045038 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 proctolin receptor binding ; GO:0071860 | inferred from physical interaction with Proc-R neuropeptide hormone activity ; GO:0005184 | inferred from direct assay positive regulation of heart rate ; GO:0010460 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG7105, Prct, PROC, PROCT, Proc, proct, Proct" "IPR004088:K Homology domain, type 1" CG7105 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" embryonic/larval heart FBgn0032492 Prosalpha6T "Proteasome alpha6 subunit, Testis-specific" http://flybase.org/reports/FBgn0032492 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332" ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR000426 sperm individualization ; GO:0007291 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype spermatid nucleus elongation ; GO:0007290 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426 cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay male germ cell nucleus ; GO:0001673 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay" "Prosalpha6T, CG5648, prosalpha6T, 5648, Alpha6T, alpha6T" "IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR023332:Proteasome alpha-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG5648 11-Aug-17 DroID_v2017_08 Drer\psma1 Scer\PRE5 Cele\pas-6 Xtro\psma1 Mmus\Psma1 Hsap\PSMA1 "viable,male sterile,recessive" "cystic bulge,spermatozoon,nucleus & elongation stage spermatid" FBgn0264085 CR43754 - http://flybase.org/reports/FBgn0264085 non_protein_coding_gene - - - "CR43754, lincRNA.14" - CR43754 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039163 CG5515 - http://flybase.org/reports/FBgn0039163 protein_coding_gene - cytoplasmic translation ; GO:0002181 | inferred from biological aspect of ancestor with PANTHER:PTN000265414 polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN000265414 CG5515 "IPR006575:RWD domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR032378:ZC3H15/TMA46 family, C-terminal" CG5515 11-Aug-17 DroID_v2017_08 "Drer\rwdd1, Drer\rwdd" Scer\GIR2 "Cele\Y53G8AR.5, Cele\T26E3.4" "Xtro\rwdd4, Xtro\rwdd1" "Mmus\Rwdd1, Mmus\Rwdd4a" "Hsap\RWDD4, Hsap\RWDD1" viable FBgn0265307 CR44280 - http://flybase.org/reports/FBgn0265307 non_protein_coding_gene - - - "CR44280, lincRNA.266" - CR44280 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005415 l(1)adl4 lethal (1) adl4 http://flybase.org/reports/FBgn0005415 - gene - - - "l(1)adl-4, l(1)adl4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,short lived,partially lethal - majority die" FBgn0003889 betaTub85D beta-Tubulin at 85D http://flybase.org/reports/FBgn0003889 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002453, InterPro:IPR008280, InterPro:IPR017975 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002453 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002453, InterPro:IPR017975 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype inferred from genetic interaction with if inferred from genetic interaction with mew microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity" "microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002453, InterPro:IPR017975 microtubule ; GO:0005874 | inferred from sequence or structural similarity" "betaTub85D, beta-tub, beta2, CG9359, BETA2, BETA 85D, D.m.BETA-85D, B2t, beta(2)Tu, beta2t, Dmbeta2, beta2tub, 2t, beta[[2]]-tubulin, beta85D, DTB4, ms(3)KK[D], betaTub2, beta-Tub85D, Tub, beta(2)Tub, beta-tub85D, beta;Tub85D, betatub85D, beta2-tub, Tub2A, BetaTub85D" "IPR000217:Tubulin, IPR002453:Beta tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain, IPR013838:Beta tubulin, autoregulation binding site" CG9359 11-Aug-17 DroID_v2017_08 "Drer\zgc:55461, Drer\tubb4b, Drer\zgc:65894, Drer\tubb2, Drer\zgc:153264, Drer\tubb2b, Drer\tubb5, Drer\zgc:153426, Drer\tubb1, Drer\tubb6" Scer\TUB2 "Cele\tbb-2, Cele\ben-1, Cele\tbb-4, Cele\mec-7, Cele\tbb-1" "Xtro\tubb4a, Xtro\tubb6, Xtro\tubb, Xtro\tubb2b, Xtro\tubb3, Xtro\tubb4b, Xtro\tube1" "Mmus\Tubb4b, Mmus\Tubb1, Mmus\Tubb3, Mmus\Tubb4a, Mmus\Tubb2b, Mmus\Tubb5, Mmus\Tube1, Mmus\Tubb2a, Mmus\Tubb6" "Hsap\TUBB3, Hsap\TUBB1, Hsap\TUBE1, Hsap\TUBB6, Hsap\TUBB4B, Hsap\TUBB2B, Hsap\TUBB2A, Hsap\TUBB4A, Hsap\TUBB, Hsap\TUBB8" " spermatogenesis && adult stage , embryonic stage , pupal stage , embryonic stage | 0-3 hr , prepupal stage , larval stage | third instar " " testis

, somatic mesoderm

{ e neur* } , somatic mesoderm

{ e E(spl)* } , somatic mesoderm

{ e amx* } , larval muscle system

{ e Dl* } , somatic mesoderm

{ e mam* } , somatic mesoderm

, somatic mesoderm

{ e Nj* } , somatic mesoderm

{ e bib* } " larval stage | third instar dorsal mesothoracic disc

"male sterile,recessive,cytokinesis defective,male fertile,meiotic cell cycle defective,wild-type,male,semidominant,electrophoretic variant,dominant,female fertile,viable" "spermatid,primary spermatocyte cyst,axoneme,spermatozoon,spermatid axoneme,microtubule,testis,microtubule & testis,spermatid & nucleus,presumptive embryonic salivary gland,meiotic cell cycle & spindle | male,meiotic cell cycle | male,spermatocyte,fusion competent cell,muscle founder cell,Nebenkern derivative,meiosis II,meiosis I,spindle & meiotic cell cycle | male,spindle,astral microtubule | male,spindle microtubule | male,spermatozoon & axoneme,seminal vesicle" DRSC16910 IE 3.47296445 -0.301228752 2.577472917 -0.737393981 -0.540914464 -0.050679354 FBgn0085369 Drgx Dorsal root ganglia homeobox http://flybase.org/reports/FBgn0085369 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 muscle organ development ; GO:0007517 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" - "CG34340, CG10017, CG2808, Drgx" "IPR001356:Homeobox domain, IPR003654:OAR domain, IPR017970:Homeobox, conserved site, IPR009057:Homeobox domain-like" CG34340 11-Aug-17 DroID_v2017_08 "Drer\phox2a, Drer\drgx, Drer\phox2bb" - "Cele\lim-7, Cele\ceh-8, Cele\ceh-17" "Xtro\phox2b, Xtro\drgx, Xtro\phox2a" "Mmus\Prrxl1, Mmus\Phox2a, Mmus\Phox2b" "Hsap\PHOX2A, Hsap\PHOX2B, Hsap\IRX5, Hsap\DRGX" viable FBgn0069151 mcl(3)Z3370 mcl(3)Z3370 http://flybase.org/reports/FBgn0069151 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3370 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0052081 CG32081 - http://flybase.org/reports/FBgn0052081 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 "CG11806, BcDNA:AT27573, CG32081, FBgn 52081" "IPR013057:Amino acid transporter, transmembrane domain" CG32081 11-Aug-17 DroID_v2017_08 "Drer\slc36a4, Drer\slc36a1" "Scer\AVT4, Scer\AVT3" "Cele\F13H10.3, Cele\slc-36.5, Cele\Y43F4B.7, Cele\skat-1, Cele\slc-36.4, Cele\slc-36.3, Cele\slc-36.2" "Xtro\slc36a4, Xtro\slc36a1" "Mmus\Slc36a4, Mmus\Slc36a3, Mmus\Slc36a2, Mmus\Slc38a9, Mmus\Slc36a1" "Hsap\SLC36A4, Hsap\SLC36A1, Hsap\SLC36A3, Hsap\SLC36A2, Hsap\SLC38A9" "viable,fertile" DRSC09861 K 0.191345641 0.484433443 -0.163845201 0.553202622 1.785168679 0.603234702 FBgn0267192 CR45632 - http://flybase.org/reports/FBgn0267192 non_protein_coding_gene - - - "CR45632, lincRNA.829" - CR45632 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036259 CG9760 - http://flybase.org/reports/FBgn0036259 protein_coding_gene - - - CG9760 - CG9760 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0041730 ovr overheated http://flybase.org/reports/FBgn0041730 gene molecular_function ; GO:0003674 | no biological data available adult locomotory behavior ; GO:0008344 | inferred from genetic interaction with comt cellular_component ; GO:0005575 | no biological data available ovr - - 11-Aug-17 DroID_v2017_08 - - - - - - "locomotor behavior defective,heat sensitive" FBgn0267729 CR46060 - http://flybase.org/reports/FBgn0267729 non_protein_coding_gene - - - CR46060 - CR46060 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085698 CG41569 - http://flybase.org/reports/FBgn0085698 protein_coding_gene - - - CG41569 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262302 mir-954 mir-954 stem loop http://flybase.org/reports/FBgn0262302 miRNA_gene - - - "mir-954, CR43009, miR-954, dme-mir-954, dme-miR-954-5p" - CR43009 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000441 dfw deflected wing http://flybase.org/reports/FBgn0000441 - gene - - - dfw - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female sterile,viable,male,female,poor,male fertile,sterile,partially lethal - majority live" "wing,eye" FBgn0260507 Pak::Pkc53E - http://flybase.org/reports/FBgn0260507 engineered_fusion_gene - - - "Pak::Pkc53E, Pak-53E" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053269 CG33269 - http://flybase.org/reports/FBgn0053269 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6100, CG14139, CG32084, CG33269" - CG33269 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004829 fir fireworks http://flybase.org/reports/FBgn0004829 - gene - - - fir - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,mitotic cell cycle defective" "neuroblast,mitotic metaphase,meiosis II,spermatid,Nebenkern derivative" FBgn0058335 CG40335 - http://flybase.org/reports/FBgn0058335 protein_coding_gene - - - CG40335 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005256 l(3)SG75 lethal (3) SG75 http://flybase.org/reports/FBgn0005256 - gene - - - l(3)SG75 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061079 l(3)S014708 lethal (3) S014708 http://flybase.org/reports/FBgn0061079 gene - - - "0147/08, l(3)S014708" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061093 l(3)S011001a lethal (3) S011001a http://flybase.org/reports/FBgn0061093 gene - - - l(3)S011001a - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031389 CG4259 - http://flybase.org/reports/FBgn0031389 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "SPH173, CG4259" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG4259 11-Aug-17 DroID_v2017_08 Drer\zgc:163025 - Cele\try-1 - "Mmus\Klk1b26, Mmus\Egfbp2, Mmus\Klk1b4, Mmus\Klk1b22, Mmus\Klkb1, Mmus\Klk1b11, Mmus\Klk1b5, Mmus\Klk1b3, Mmus\Klk1, Mmus\Klk1b27, Mmus\Klk1b16, Mmus\Klk1b21, Mmus\Klk1b8, Mmus\Klk1b24, Mmus\Klk11, Mmus\F11, Mmus\Klk1b9, Mmus\Klk1b1" "Hsap\KLK11, Hsap\KLK1, Hsap\KLK3, Hsap\KLKB1, Hsap\F11, Hsap\KLK2" viable FBgn0034191 CG6984 - http://flybase.org/reports/FBgn0034191 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001753, InterPro:IPR018376" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR001753, InterPro:IPR018376" - CG6984 "IPR001753:Crotonase superfamily, IPR018376:Enoyl-CoA hydratase/isomerase, conserved site, IPR014748:Crontonase, C-terminal, IPR029045:ClpP/crotonase-like domain" CG6984 11-Aug-17 DroID_v2017_08 Drer\echdc3 "Scer\ECI1, Scer\DCI1" Cele\ech-2 Xtro\echdc3 Mmus\Echdc3 Hsap\ECHDC3 viable DRSC07013 I 6.422902345 -0.830144718 -0.335946628 0.692738551 -0.271182461 -0.297267751 FBgn0265413 CG44325 - http://flybase.org/reports/FBgn0265413 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44325, CG15366, CG7267" - CG44325 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041786 S(Sev-CycE)D16 S(Sev-CycE)D16 http://flybase.org/reports/FBgn0041786 gene - - - S(Sev-CycE)D16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011880 tRNA:Ile-AAT-1-1 transfer RNA:Isoleucine-AAT 1-1 http://flybase.org/reports/FBgn0011880 "FBgn0050313, FBgn0060202" tRNA_gene AUU codon-amino acid adaptor activity ; GO:0033433 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033433 cytosol ; GO:0005829 | inferred by curator from GO:0033433 "tRNA Ile, AE002769.trna15-IleAAT, tRNA:I:AAT:AE002769, tRNA:ile:42A, CR30313, tRNA[Ile], chr2R.trna7-IleAAT, tRNA-Ile[AAU], tRNA-Ile-AAT-1-1, tRNA:Ile-AAT-1-1, tRNA:I:42A, AUU" - CR30313 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020813 l(4)Fox lethal (4) Fox http://flybase.org/reports/FBgn0020813 - gene - - - l(4)Fox - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264947 CR44116 - http://flybase.org/reports/FBgn0264947 non_protein_coding_gene - - - CR44116 - CR44116 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266570 CG2982 - http://flybase.org/reports/FBgn0266570 protein_coding_gene "histone demethylase activity (H3-K36 specific) ; GO:0051864 | inferred from sequence or structural similarity with UniProtKB:Q9JJF3 iron ion binding ; GO:0005506 | inferred from sequence or structural similarity with UniProtKB:Q9JJF3 histone demethylase activity (H3-K4 specific) ; GO:0032453 | inferred from sequence or structural similarity with UniProtKB:Q9JJF3 histone demethylase activity (H3-K36 specific) ; GO:0051864 | inferred from biological aspect of ancestor with PANTHER:PTN000318179 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors ; GO:0016706 | inferred from sequence or structural similarity with UniProtKB:Q9JJF3 histone demethylase activity (H3-K4 specific) ; GO:0032453 | inferred from biological aspect of ancestor with PANTHER:PTN000318179" "peptidyl-arginine hydroxylation ; GO:0030961 | inferred from biological aspect of ancestor with PANTHER:PTN001773197 histone H3-K4 demethylation ; GO:0034720 | inferred from sequence or structural similarity with UniProtKB:Q9JJF3 histone H3-K36 demethylation ; GO:0070544 | inferred from sequence or structural similarity with UniProtKB:Q9JJF3 negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from biological aspect of ancestor with PANTHER:PTN000991806 negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q9JJF3 chromatin remodeling ; GO:0006338 | inferred from biological aspect of ancestor with PANTHER:PTN000318179" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9JJF3 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000991806 "CG2982, anon-4Bd" "IPR003347:JmjC domain, IPR013109:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66" CG2982 11-Aug-17 DroID_v2017_08 "Drer\zgc:162967, Drer\minal" - Cele\jmjc-1 "Xtro\mina, Xtro\c14orf169" "Mmus\Mina, Mmus\2410016O06Rik" "Hsap\MINA, Hsap\C14orf169" FBgn0030270 CG15199 - http://flybase.org/reports/FBgn0030270 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from biological aspect of ancestor with PANTHER:PTN002219240 extracellular space ; GO:0005615 | inferred from sequence model "CG15199, DIGF-3" IPR029277:Single domain Von Willebrand factor type C domain CG15199 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002768 mit(1)20 mitotic 20 http://flybase.org/reports/FBgn0002768 - gene - - - mit(1)20 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069955 CG41065 - http://flybase.org/reports/FBgn0069955 protein_coding_gene - - - CG41065 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015986 l(2)PC4-P lethal (2) PC4-P http://flybase.org/reports/FBgn0015986 - gene - - - l(2)PC4-P - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267026 CR45470 - http://flybase.org/reports/FBgn0267026 pseudogene_attribute - - - CR45470 - CR45470 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005151 l(2)G84 lethal (2) G84 http://flybase.org/reports/FBgn0005151 - gene - - - l(2)G84 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0023400 C55 C55 http://flybase.org/reports/FBgn0023400 - gene - - - C55 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004041 yea7 yeast 7 http://flybase.org/reports/FBgn0004041 - gene - - - yea7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045474 Gr77a Gustatory receptor 77a http://flybase.org/reports/FBgn0045474 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr77E1, 77E.1, CG32433, GR77E.1, Gr77a, GR77a" IPR013604:7TM chemoreceptor CG32433 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - FBgn0264844 CR44052 - http://flybase.org/reports/FBgn0264844 non_protein_coding_gene - - - CR44052 - CR44052 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004544 l(4)102CDo lethal (4) 102CDo http://flybase.org/reports/FBgn0004544 - gene - - - "l(4)CDo, l(4)30, l(4)102CDo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0001551 l(1)18Fa lethal (1) 18Fa http://flybase.org/reports/FBgn0001551 - gene - - - "l(1)HC233, l(1)18Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031514 CG3332 - http://flybase.org/reports/FBgn0031514 protein_coding_gene - - - CG3332 IPR004878:Otopetrin CG3332 11-Aug-17 DroID_v2017_08 "Drer\otop1, Drer\otop2" - "Cele\otpl-6, Cele\otpl-7, Cele\otpl-2, Cele\otpl-3, Cele\otpl-8, Cele\otpl-4, Cele\otpl-1, Cele\otpl-5" "Xtro\otop3, Xtro\otop2, Xtro\otop1" "Mmus\Otop3, Mmus\Otop1, Mmus\Otop2" "Hsap\OTOP2, Hsap\OTOP1, Hsap\OTOP3" "visible,viable" "wing,mesothoracic tergum" DRSC00594 I -0.016380007 -2.205016852 -0.532506015 -0.016646432 1.086811359 0.775698678 FBgn0037739 CG12948 - http://flybase.org/reports/FBgn0037739 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12948 IPR028019:Protein of unknown function DUF4508 CG12948 11-Aug-17 DroID_v2017_08 Drer\si:ch211-14a17.11 - - Xtro\c14orf119 Mmus\1700123O20Rik Hsap\C14orf119 viable FBgn0016014 l(3)64Am lethal (3) 64Am http://flybase.org/reports/FBgn0016014 - gene - - - "l(3)SH13, l(3)64Am" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0066332 prem premjera http://flybase.org/reports/FBgn0066332 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available prem - - 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,chemical sensitive" FBgn0003911 Tyr2 Tyrosine 2 http://flybase.org/reports/FBgn0003911 - gene - - - "Tyr-2, Tyr2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265920 CR44709 - http://flybase.org/reports/FBgn0265920 non_protein_coding_gene - - - "CR44709, lincRNA.433, lincRNA.434" - CR44709 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000867 fs(1)M62 female sterile (1) M62 http://flybase.org/reports/FBgn0000867 - gene - - - fs(1)M62 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0267422 CR45775 - http://flybase.org/reports/FBgn0267422 pseudogene_attribute - - - "CR45775, Mst77Y" - CR45775 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011871 tRNA:Gly-GCC-1-12 transfer RNA:Glycine-GCC 1-12 http://flybase.org/reports/FBgn0011871 "FBgn0003783, FBgn0050207, FBgn0060227" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "CR30207, AE002575.trna13-GlyGCC, tRNA:G:GCC:AE002575-b, tRNA:gly3:57BCa, tRNA[Gly-GCC], chr2R.trna57-GlyGCC, tRNA-Gly-GCC-1-12, tRNA:Gly-GCC-1-12, tRNA:G3:57BCa, GGC" - CR30207 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004999 crip cripple http://flybase.org/reports/FBgn0004999 - gene - - - crip - - 11-Aug-17 DroID_v2017_08 - - - - - - visible leg FBgn0020906 Jon25Bi Jonah 25Bi http://flybase.org/reports/FBgn0020906 "FBgn0001284, FBtr0079054, FBpp0078690" protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 endopeptidase activity ; GO:0004175 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "25B, Ser4, SP137, CG8867, Jon25B, Jon25Bi, Jon25" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG8867 11-Aug-17 DroID_v2017_08 - - - - - Hsap\KLK3 larval stage | third instar embryonic/larval digestive system | restricted

"viable,visible" trichogen cell FBgn0085638 CG41378 - http://flybase.org/reports/FBgn0085638 protein_coding_gene - - - CG41378 IPR004911:Gamma interferon inducible lysosomal thiol reductase GILT CG41378 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-197i20.6, Drer\ifi30" - "Cele\ZK669.2, Cele\F37H8.5, Cele\R07E5.4, Cele\W04A4.3, Cele\Y18D10A.2, Cele\pqn-48, Cele\ZK669.3, Cele\C02D5.2" Xtro\ifi30 Mmus\Ifi30 Hsap\IFI30 FBgn0020570 anon-85Cb anon-85Cb http://flybase.org/reports/FBgn0020570 - gene - - - anon-85Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011126 l(1)Q89 lethal (1) Q89 http://flybase.org/reports/FBgn0011126 FBgn0010210 gene - - - l(1)Q89 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037138 P5CDh1 delta-1-Pyrroline-5-carboxylate dehydrogenase 1 http://flybase.org/reports/FBgn0037138 protein_coding_gene 1-pyrroline-5-carboxylate dehydrogenase activity ; GO:0003842 | inferred from sequence or structural similarity with UniProtKB:P30038 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016160, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163, InterPro:IPR029510 glutamate biosynthetic process ; GO:0006537 | inferred from electronic annotation with InterPro:IPR005931 proline biosynthetic process ; GO:0006561 | inferred from electronic annotation with InterPro:IPR005931 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype proline metabolic process ; GO:0006560 | inferred from sequence or structural similarity with UniProtKB:P30038 proline metabolic process ; GO:0006560 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P30038 "CG7145, P5CDh1, DmP5CDh1, P5CDh" "IPR005931:Delta-1-pyrroline-5-carboxylate dehydrogenase, IPR015590:Aldehyde dehydrogenase domain, IPR016160:Aldehyde dehydrogenase, cysteine active site, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR029510:Aldehyde dehydrogenase, glutamic acid active site" CG7145 11-Aug-17 DroID_v2017_08 "Drer\iffo2a, Drer\aldh4a1" Scer\PUT2 Cele\alh-6 Xtro\aldh4a1 "Mmus\Aldh4a1, Mmus\Iffo2" "Hsap\IFFO2, Hsap\ALDH4A1" "lethal,recessive,developmental rate defective,body size defective,viable" mitochondrion FBgn0041240 Gr57a Gustatory receptor 57a http://flybase.org/reports/FBgn0041240 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr57B1, CG13441, 57B.1, GR57B.1, Gr57a, GR57a" IPR013604:7TM chemoreceptor CG13441 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0262394 mir-281-1 mir-281-1 stem loop http://flybase.org/reports/FBgn0262394 miRNA_gene - - - "mir-281, mir-281-1, miR-281-1, MIR-281, CR42931, CR33594, miR-281a, mir-281a, miR-281, CR33592, dme-mir-281-1, dme-miR-281-1, CR33595, miR-281aS, mir-281aS, mir-281-1*, dme-miR-281" - CR42931 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0019703 l(2)50CDa lethal (2) 50CDa http://flybase.org/reports/FBgn0019703 - gene - - - l(2)50CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023061 l(1)2Dl lethal (1) 2Dl http://flybase.org/reports/FBgn0023061 - gene - - - "E3/36.11, C2/5.11, B2/34.27, l(1)2Dl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050227 tRNA:Trp-CCA-2-2 transfer RNA:Tryptophan-CCA 2-2 http://flybase.org/reports/FBgn0050227 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "CR30227, AE002787.trna48-TrpCCA, tRNA:W:CCA:AE002787-b, chr2R.trna31-TrpCCA, tRNA-Trp-CCA-2-2, tRNA:Trp-CCA-2-2, tRNA:CR30227, UGG" - CR30227 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024270 ZAM\pol ZAM element pol http://flybase.org/reports/FBgn0024270 - transposable_element_gene integrase activity ; GO:0008907 | inferred from direct assay nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "ORF2, ZAM\pol, pol, ZAM-IN" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266618 CR45125 - http://flybase.org/reports/FBgn0266618 non_protein_coding_gene - - - CR45125 - CR45125 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069125 mir-P323-1 mir-P323-1 http://flybase.org/reports/FBgn0069125 miRNA_gene - - - mir-P323-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040729 CG15126 - http://flybase.org/reports/FBgn0040729 protein_coding_gene - - - CG15126 - CG15126 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003741 tra transformer http://flybase.org/reports/FBgn0003741 - protein_coding_gene pre-mRNA binding ; GO:0036002 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with tra2 "male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype sex determination ; GO:0007530 | traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred from direct assay female somatic sex determination ; GO:0019101 | traceable author statement RNA splicing ; GO:0008380 | traceable author statement somatic sex determination ; GO:0018993 | non-traceable author statement spliceosomal complex assembly ; GO:0000245 | non-traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | traceable author statement female sex determination ; GO:0030237 | inferred from mutant phenotype sex differentiation ; GO:0007548 | traceable author statement female sex differentiation ; GO:0046660 | inferred from direct assay negative regulation of translation ; GO:0017148 | non-traceable author statement" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR010519 "TRA, Dmtra, CG16724, tra, Tra" IPR010519:Female-specific protein transformer CG16724 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage -- adult stage , larval stage--adult stage | female , pupal stage--adult stage " organism

"female sterile,male fertile,viable,fertile,visible,male limited,wild-type,sex-determination defective,dominant,neuroanatomy defective,male,courtship behavior defective,sterile,recessive,female,locomotor behavior defective,mating defective,behavior defective,reduced,male sterile,partially,song defective,mating behavior defective" "germline cell,adult external abdomen,male reproductive system,spermatocyte fusome,spermatocyte ring canal,ovary,male genitalia,sex comb,gonad,adult brain & neuron | medial | female,gonadal sheath proper primordium,female,spectrosome,fusome,nurse cell ring canal,serotonergic neuron,adult fruitless pMP-e (female) neuron,ectopic,hub cell,adult brain,female genitalia,male,prothoracic leg taste bristle,adult nervous system,male genital disc,female genital disc,female repressed primordium,antennal lobe glomerulus DA1,abdomen,seminal receptacle,spermathecum,testis,spermatozoon,germline cell | embryonic stage,flight muscle,male limited" FBgn0052985 CG32985 - http://flybase.org/reports/FBgn0052985 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850 molecular_function ; GO:0003674 | no biological data available" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" cellular_component ; GO:0005575 | no biological data available "CG17789, CG32985, gi22945998, gi21430910" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG32985 11-Aug-17 DroID_v2017_08 - - "Cele\R03G8.3, Cele\F07C3.3, Cele\M03F8.5, Cele\F32D8.2, Cele\Y73F8A.35, Cele\F15H10.7, Cele\F32G8.2, Cele\T07G12.3, Cele\F10C2.3, Cele\Y38A10A.2, Cele\Y41E3.1, Cele\K03A11.4, Cele\R03G8.1, Cele\T23E1.1" - - - viable FBgn0010091 Su(vg)B27 Suppressor of vestigial B27 http://flybase.org/reports/FBgn0010091 - gene - - - "vg[BUR27], vg[[BUR27]], Su(vg)B27" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083044 snoRNA:Psi18S-1397 snoRNA:Psi18S-1397 http://flybase.org/reports/FBgn0083044 snoRNA_gene - - - "snoRNA:Psi18S-1397, Psi18S-1397, psi18S-1397, Psi 18S-1397, CR34637, chr3L:5736789..5736893" - CR34637 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266761 shg::Mmus\cdh1 - http://flybase.org/reports/FBgn0266761 engineered_fusion_gene - - - shg::Mmus\cdh1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000783 fs(1)A1559 female sterile (1) A1559 http://flybase.org/reports/FBgn0000783 - gene - - - fs(1)A1559 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0000653 ff fluff http://flybase.org/reports/FBgn0000653 - gene - - - ff - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile" "macrochaeta,wing" FBgn0031829 IFT52 Intraflagellar transport 52 http://flybase.org/reports/FBgn0031829 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with MGI:MGI:2387217 cilium assembly ; GO:0060271 | inferred from sequence model cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:2387217 intraciliary transport particle ; GO:0030990 | inferred from sequence or structural similarity with UniProtKB:Q946G4 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:2387217 "CG9595, IFT52, NGD5, OSM-6, osm-6, Osm-6, Osm6" IPR029062:Class I glutamine amidotransferase-like CG9595 11-Aug-17 DroID_v2017_08 Drer\ift52 - Cele\osm-6 Xtro\ift52 Mmus\Ift52 Hsap\IFT52 viable FBgn0266936 CR45387 - http://flybase.org/reports/FBgn0266936 non_protein_coding_gene - - - CR45387 - CR45387 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267284 CR45720 - http://flybase.org/reports/FBgn0267284 non_protein_coding_gene - - - "lincRNA.32, CR45720" - CR45720 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003954 unexpanded-irregular unexpanded irregular http://flybase.org/reports/FBgn0003954 - gene - - - "unexpanded-irregular, unr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,fertile,reduced" wing FBgn0261110 G38 - http://flybase.org/reports/FBgn0261110 gene - - - G38 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0261109 mrn marionette http://flybase.org/reports/FBgn0261109 protein_coding_gene "ATP-dependent DNA helicase activity ; GO:0004003 | inferred from electronic annotation with InterPro:IPR004598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000322344 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN000322344 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000322344 transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675 ATPase activator activity ; GO:0001671 | inferred from direct assay" nucleotide-excision repair ; GO:0006289 | inferred from direct assay transcriptional open complex formation at RNA polymerase II promoter ; GO:0001113 | inferred from sequence or structural similarity with HGNC:4658 nucleotide-excision repair ; GO:0006289 | inferred from direct assay inferred from mutant phenotype response to UV-B ; GO:0010224 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4658 inferred from sequence or structural similarity with SGD:S000006043 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay phosphorylation of RNA polymerase II C-terminal domain ; GO:0070816 | inferred from biological aspect of ancestor with PANTHER:PTN000322344 promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from sequence or structural similarity with HGNC:4658 "core TFIIH complex ; GO:0000439 | inferred from physical interaction with Xpd holo TFIIH complex ; GO:0005675 | inferred from direct assay core TFIIH complex ; GO:0000439 | inferred from sequence or structural similarity with SGD:S000006043 nucleus ; GO:0005634 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:4658 inferred from sequence or structural similarity with SGD:S000006043 holo TFIIH complex ; GO:0005675 | inferred from physical interaction with hay, CycH, Mat1, Xpd, Cdk7" "Tfb2, 154538_at, TFB2, CG7764, p52, anon-WO0118547.648, nc16, ms(3)nc16, l(3)E35, mrn, Dmp52" IPR004598:Transcription factor TFIIH subunit p52/Tfb2 CG7764 11-Aug-17 DroID_v2017_08 Drer\gtf2h4 Scer\TFB2 Cele\Y73F8A.24 "Xtro\LOC101731871, Xtro\gtf2h4" Mmus\Gtf2h4 Hsap\GTF2H4 FBgn0034031 CG12963 - http://flybase.org/reports/FBgn0034031 protein_coding_gene - - - "BcDNA:AT28470, CG12963" - CG12963 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036818 CG14074 - http://flybase.org/reports/FBgn0036818 protein_coding_gene - - - CG14074 - CG14074 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263585 CR43610 - http://flybase.org/reports/FBgn0263585 non_protein_coding_gene - - - "CR43610, lincRNA.59" - CR43610 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259216 RhoGAP102A Rho GTPase activating protein at 102A http://flybase.org/reports/FBgn0259216 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with MGI:MGI:1196332 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with MGI:MGI:1196332" cellular_component ; GO:0005575 | no biological data available "CG42316, CG1748, RhoGAP102A, BP1050, CG34013, Dm_4:1183, mlncRNA102B1, rhoGAP102A" "IPR000198:Rho GTPase-activating protein domain, IPR008936:Rho GTPase activation protein" CG42316 11-Aug-17 DroID_v2017_08 "Drer\arhgap6, Drer\chn1, Drer\arhgap11a, Drer\zgc:153345, Drer\chn2, Drer\LOC100005008" "Scer\LRG1, Scer\BEM3, Scer\SAC7, Scer\BAG7" "Cele\chin-1, Cele\rga-6" "Xtro\arhgap6, Xtro\arhgap11a.1, Xtro\chn2, Xtro\chn1, Xtro\arhgap11a.2" "Mmus\Arhgap36, Mmus\Arhgap6, Mmus\Arhgap11a, Mmus\Chn2, Mmus\Chn1" "Hsap\CHN2, Hsap\ARHGAP36, Hsap\ARHGAP11A, Hsap\CHN1, Hsap\ARHGAP11B, Hsap\ARHGAP6" FBgn0052481 tRNA:Ile-TAT-1-2 transfer RNA:Isoleucine-TAT 1-2 http://flybase.org/reports/FBgn0052481 tRNA_gene AUA codon-amino acid adaptor activity ; GO:0033435 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033435 cytosol ; GO:0005829 | inferred by curator from GO:0033435 "CR32481, AE002584.trna2-IleTAT, tRNA:I:TAT:AE002584-b, chr3L.trna2-IleTAT, tRNA-Ile-TAT-1-2, tRNA:Ile-TAT-1-2, tRNA:CR32481, AUA" - CR32481 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038821 CG17267 - http://flybase.org/reports/FBgn0038821 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17267 - CG17267 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065145 l(3)SH091 lethal (3) SH091 http://flybase.org/reports/FBgn0065145 gene - - - "l(3)SH091, l(2)SH3 091" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051086 CG31086 - http://flybase.org/reports/FBgn0051086 protein_coding_gene - - - "CG14558, CG31086" "IPR006616:DM9 repeat, IPR024518:Domain of unknown function DUF3421" CG31086 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028567 robl62A robl62A http://flybase.org/reports/FBgn0028567 protein_coding_gene "dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity dynein intermediate chain binding ; GO:0045505 | inferred from sequence or structural similarity with robl" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with robl cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR016561 dynein complex ; GO:0030286 | inferred from sequence or structural similarity with robl dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG1014, robl62A, rob162A" "IPR016561:Dynein light chain roadblock-type 1/2, IPR004942:Roadblock/LAMTOR2 domain" CG1014 11-Aug-17 DroID_v2017_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb2, Mmus\Dynlrb1" "Hsap\DYNLRB2, Hsap\DYNLRB1" FBgn0060730 l(3)S067309 lethal (3) S067309 http://flybase.org/reports/FBgn0060730 gene - - - "0673/09, l(3)S067309" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0052343 Atac3 Ada2a-containing complex component 3 http://flybase.org/reports/FBgn0052343 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001195199 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN001195199 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay" histone acetylation ; GO:0016573 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN001195199 chromatin remodeling ; GO:0006338 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from physical interaction with Ada2a "cg6994, CG6994, dATAC3, CG32343, Atac3" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG32343 11-Aug-17 DroID_v2017_08 "Drer\gabpb2a, Drer\gabpb2b, Drer\gabpb1, Drer\ddx54" "Scer\YAR1, Scer\DBP10" - "Xtro\ddx54, Xtro\gabpb2, Xtro\gabpb1" "Mmus\Gabpb2, Mmus\Ddx54, Mmus\Gabpb1" "Hsap\FLJ10038, Hsap\ANKRD62, Hsap\DDX54, Hsap\GABPB2" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0030330 Tango10 Transport and Golgi organization 10 http://flybase.org/reports/FBgn0030330 protein_coding_gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG1841, TANGO10, Tango10, tango10" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR011705:BTB/Kelch-associated" CG1841 11-Aug-17 DroID_v2017_08 "Drer\lgals3bpb, Drer\btbd6b, Drer\lgals3bpa, Drer\btbd6a, Drer\btbd3b, Drer\btbd2, Drer\zgc:112492, Drer\btbd3a, Drer\btbd17a, Drer\btbd17b" - Cele\W07A12.4 "Xtro\btbd2, Xtro\btbd3, Xtro\btbd1, Xtro\btbd6, Xtro\btbd17" "Mmus\Btbd17, Mmus\Lgals3bp, Mmus\Btbd3, Mmus\Btbd1, Mmus\Btbd2, Mmus\Btbd6" "Hsap\BTBD1, Hsap\BTBD3, Hsap\BTBD6, Hsap\LGALS3BP, Hsap\BTBD2, Hsap\BTBD17" DRSC19807 IE -0.172547307 3.120933771 -1.077524622 -1.735624488 -0.033408575 -0.265975694 FBgn0040054 CG12475 - http://flybase.org/reports/FBgn0040054 protein_coding_gene - - - CG12475 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265513 E(comt[6])21E - http://flybase.org/reports/FBgn0265513 gene - - - E(comt[6])21E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010662 l(2)10481 lethal (2) 10481 http://flybase.org/reports/FBgn0010662 FBgn0010533 gene - - - "l(2)03263, l(2)10481" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0004427 LysD Lysozyme D http://flybase.org/reports/FBgn0004427 FBgn0002575 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from sequence or structural similarity chitinase activity ; GO:0004568 | inferred from direct assay lysozyme activity ; GO:0003796 | inferred from direct assay - - "LysD, lysD, CG9118" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CG9118 11-Aug-17 DroID_v2017_08 "Drer\LOC100536671, Drer\lyz, Drer\LOC100334363" - - Xtro\MGC89221 "Mmus\Spaca5, Mmus\Lyz1, Mmus\Lyzl1, Mmus\Spaca4, Mmus\Spaca7, Mmus\9530003J23Rik, Mmus\1700016D06Rik, Mmus\Lyzl6, Mmus\Lalba, Mmus\Spaca3, Mmus\Spaca1, Mmus\Lyzl4, Mmus\Lyz2" "Hsap\SPACA4, Hsap\SPACA1, Hsap\SPACA5B, Hsap\SPACA5, Hsap\LYZL2, Hsap\LYZ, Hsap\LYZL1, Hsap\SPACA7, Hsap\LALBA, Hsap\LYZL6, Hsap\LYZL4, Hsap\SPACA3" " larval stage , adult stage , larval stage && pupal stage && adult stage , larval stage && adult stage " " gastric caecum

, adult midgut | anterior

, embryonic/larval midgut

, adult midgut

, anterior embryonic/larval midgut

" FBgn0266626 CR45133 - http://flybase.org/reports/FBgn0266626 non_protein_coding_gene - - - CR45133 - CR45133 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259278 EP-720 - http://flybase.org/reports/FBgn0259278 gene - - - EP-720 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing" FBgn0020885 Tbf1 TE1 binding factor 1 http://flybase.org/reports/FBgn0020885 - gene DNA binding ; GO:0003677 | inferred from direct assay - - "TBF1, Tbf1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264986 CR44137 - http://flybase.org/reports/FBgn0264986 non_protein_coding_gene - - - CR44137 - CR44137 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027126 l(3)IH4 lethal (3) IH4 http://flybase.org/reports/FBgn0027126 - gene - - - l(3)IH4 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044017 Scad67 Suppressor of constitutively activated Dpp signaling 67 http://flybase.org/reports/FBgn0044017 gene - - - Scad67 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039970 CG17508 - http://flybase.org/reports/FBgn0039970 protein_coding_gene - - - CG17508 IPR009688:Domain of unknown function DUF1279 CG17508 11-Aug-17 DroID_v2017_08 Drer\fam210b Scer\NAT2 Cele\Y56A3A.22 - Mmus\Fam210b Hsap\FAM210B "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0067752 l(1)G0187 lethal (1) G0187 http://flybase.org/reports/FBgn0067752 gene - - - l(1)G0187 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "wing,chaeta" FBgn0001634 l(1)dn14 lethal (1) discs normal 14 http://flybase.org/reports/FBgn0001634 - gene - - - "l(1)d.norm.-14, l(1)dn14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039342 CG5107 - http://flybase.org/reports/FBgn0039342 protein_coding_gene - - - "anon-WO0140519.57, CG5107" - CG5107 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0021921 l(2)k11301 lethal (2) k11301 http://flybase.net/reports/FBgn0021921.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0085815 CR41605 - http://flybase.org/reports/FBgn0085815 rRNA_gene - - - CR41605 - CR41605 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050384 CG30384 - http://flybase.org/reports/FBgn0050384 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG11074, CG30384" IPR032707:MYCBP-associated protein CG30384 11-Aug-17 DroID_v2017_08 Drer\mycbpap - - - Mmus\Mycbpap - viable FBgn0053062 CG33062 - http://flybase.org/reports/FBgn0053062 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD02058, CG33062" - CG33062 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050105 CG30105 - http://flybase.org/reports/FBgn0050105 protein_coding_gene molecular_function ; GO:0003674 | no biological data available RNA catabolic process ; GO:0006401 | inferred from electronic annotation with InterPro:IPR013924 biological_process ; GO:0008150 | no biological data available ribonuclease H2 complex ; GO:0032299 | inferred from electronic annotation with InterPro:IPR013924 cellular_component ; GO:0005575 | no biological data available "CG30105, BcDNA:RE11282" "IPR013924:Ribonuclease H2, subunit C" CG30105 11-Aug-17 DroID_v2017_08 Drer\rnaseh2c - Cele\ZK1127.13 Xtro\rnaseh2c Mmus\Rnaseh2c Hsap\RNASEH2C viable DRSC05668 K 0.054141047 0.019714824 0.192379554 0.265321676 -0.273559115 1.528921631 FBgn0019661 roX1 RNA on the X 1 http://flybase.org/reports/FBgn0019661 "FBgn0015564, FBgn0052777, FBgn0063259" non_protein_coding_gene - dosage compensation ; GO:0007549 | traceable author statement dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome ; GO:0016457 | non-traceable author statement dosage compensation by hyperactivation of X chromosome ; GO:0009047 | traceable author statement negative regulation of chromatin silencing ; GO:0031936 | inferred from genetic interaction with roX2 dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome ; GO:0016457 | inferred from mutant phenotype "X chromosome ; GO:0000805 | traceable author statement X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | traceable author statement X chromosome ; GO:0000805 | non-traceable author statement MSL complex ; GO:0072487 | inferred from direct assay" "roX1, roX, rox1, EG:EG0002.2, CR32777, BcDNA:GH10432, chrX:3706836..3706970, RoX1, rox-1" - CR32777 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage | male , embryonic stage | stage >=5 , larval stage | third instar , spermatogenesis && adult stage , embryonic stage | stage 5-13 " " adult fat body

, embryonic brain

, interneuron &&of antennal lobe

, neuron &&of antennal segment 3

, embryonic/larval garland cell

, ejaculatory bulb

, ring gland

, cell body &&of adult brain

, ventral nerve cord

, thoracico-abdominal ganglion

, optic lobe neuron

, pupal/adult digestive system

, photoreceptor cell

, male reproductive system

, adult brain

, embryonic/larval salivary gland

, cell body &&of mushroom body

, gastric caecum

" "viable,fertile,lethal" FBgn0000577 en engrailed http://flybase.org/reports/FBgn0000577 "FBgn0003492, FBgn0014157, FBgn0016969" protein_coding_gene "RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "compartment pattern specification ; GO:0007386 | non-traceable author statement gonad development ; GO:0008406 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | traceable author statement segment polarity determination ; GO:0007367 | non-traceable author statement genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern ventral midline development ; GO:0007418 | inferred from mutant phenotype wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement compartment pattern specification ; GO:0007386 | traceable author statement trunk segmentation ; GO:0035290 | traceable author statement imaginal disc-derived female genitalia development ; GO:0007486 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement anterior/posterior lineage restriction, imaginal disc ; GO:0048099 | traceable author statement posterior compartment specification ; GO:0007388 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype anterior/posterior pattern specification, imaginal disc ; GO:0007448 | traceable author statement anterior commissure morphogenesis ; GO:0021960 | inferred from mutant phenotype analia development ; GO:0007487 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype imaginal disc-derived male genitalia development ; GO:0007485 | traceable author statement posterior head segmentation ; GO:0035289 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype anterior head segmentation ; GO:0035288 | traceable author statement imaginal disc pattern formation ; GO:0007447 | traceable author statement genital disc development ; GO:0035215 | inferred from mutant phenotype genital disc anterior/posterior pattern formation ; GO:0035224 | traceable author statement imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | inferred from genetic interaction with gsb, inv inferred from genetic interaction with gsb, inv, ptc" nucleus ; GO:0005634 | inferred from direct assay "en, En, 153867_at, Eng, Engrailed/Invected, spt, Engrailed, V, Es, CG9015, Apa, EN, EnR, Engr, en1, spa2, engrailed" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR000747:Homeobox domain engrailed, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR019549:Homeobox engrailed, C-terminal, IPR019737:Homeobox engrailed-type, conserved site, IPR020479:Homeobox domain, metazoa, IPR020683:Ankyrin repeat-containing domain" CG9015 11-Aug-17 DroID_v2017_08 "Drer\eng2a, Drer\eng1b, Drer\eng1a, Drer\eng2b" Scer\RSC58 "Cele\ceh-58, Cele\ceh-41, Cele\ceh-16" "Xtro\en2, Xtro\en1" "Mmus\Cphx3, Mmus\En1, Mmus\Cphx1, Mmus\Cphx2, Mmus\En2" "Hsap\HOXA13, Hsap\EN2, Hsap\HOXB13, Hsap\EN1, Hsap\HOXC13, Hsap\HOXD13" " larval stage , embryonic stage--pupal stage , larval stage | third instar , embryonic stage | stage >= 6 , embryonic stage | stage 5 , embryonic stage | 3-12 hr " " ventral thoracic disc

, ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, dorsal metathoracic disc

,

segment polarity , dorsal mesothoracic disc

,

60% egg length " " embryonic stage | stage 11 , embryonic stage | stage 7-11 , embryonic stage , larval stage | third instar , embryonic stage | stage 8-11 , embryonic stage | stage 7 , embryonic stage | stage 8 , embryonic stage | stage >=8 , embryonic stage | stage 12-15 , embryonic stage | stage 9-11 , embryonic stage | stage 6 , embryonic stage | stage 10,11 " " ventral nervous system | posterior & segmentally repeated

, parasegment | restricted

segmentally repeated , ectoderm

, female genital disc | restricted

, neuroblast NB7-1

, parasegment 2--15

, embryonic gnathal segment | posterior <

, male genital disc | restricted

, labral segment

, intercalary segment

,

posterior | segmentally repeated , antennal segment

, epidermis | segmentally repeated

, embryonic thoracic segment | posterior <

, ectoderm

{ v arm* } , head

, neuroblast NB7-2

, embryonic abdominal segment 1--9 | posterior

, neuroblast NB7-4

, embryonic maxillary segment | posterior

, central nervous system | segmentally repeated

, embryonic maxillary segment | posterior && embryonic labial segment | posterior && embryonic thoracic segment | posterior && embryonic abdominal segment 1--7 | posterior

, neuroblast NB6-2

,

segmentally repeated , neuroblast NB6-1

, neuroblast NB1-1

" "visible,lethal,recessive,viable,sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,heat sensitive,dominant,neuroanatomy defective,pair rule phenotype,fertile,female,reduced,lethal - all die during embryonic stage,embryonic/larval segmentation phenotype,planar polarity defective,segment polarity phenotype,some die during third instar larval stage,some die during pupal stage,lethal - all die before end of pupal stage,partially lethal - majority die" "wing vein,anterior crossvein,posterior crossvein,wing,wing vein L5,gonad,gonadal sheath proper primordium,second segment of antenna,posterior compartment,prothoracic tibial transverse row bristle,posterior,wing vein L3,campaniform sensillum of anterior crossvein,sensillum campaniformium,scutellum,prothoracic leg,wing disc,somatic clone,anterior/posterior compartment boundary,wing vein L4,sex comb,ectopic,metathoracic tibial transverse bristle row,antenna,third segment of antenna,wing & macrochaeta,hypandrium,penis,genital arch,clasper,female gonopod,prothoracic tarsal segment,mesothoracic tarsal bristle longitudinal row 2,mesothoracic tarsal bristle longitudinal row 2.5,trichome of the posterior wing margin,alula,tergite,neuroblast NB7-3,presumptive embryonic/larval central nervous system,EL neuron,embryonic epidermis,heat sensitive,denticle belt,embryonic head,cephalopharyngeal skeleton,abdominal tergite & trichome,abdominal tergite & macrochaeta,adult abdomen,haltere,anterior compartment,male genitalia,male terminalia sensillum,hypandrial process,basal apodeme of penis,hypandrial bristle,gonopod thorn bristle,gonopod long bristle,abdominal tergite | anterior & trichome,anterior,embryonic/first instar larval cuticle,proboscis,leg,lateral plate,anal plate,central nervous system,epidermis,Keilin's organ,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,longitudinal connective,commissure,presumptive embryonic/larval muscle system,embryonic/larval central nervous system,embryonic/larval peripheral nervous system,serotonergic neuron,segment,cuticle,apodeme,embryonic/larval somatic muscle,embryonic abdomen,ventral nerve cord,posterior commissure,anterior commissure,lateral tract,metathoracic ventral denticle belt,embryonic gnathal segment,embryonic/larval fat body,stigmatophore,genital disc primordium,terminal filament,embryonic metathoracic segment,embryonic abdominal segment 2,embryonic prothoracic segment,embryonic abdominal segment 4,abdominal segment 6,abdominal segment 8,embryonic segment,cell non-autonomous,embryonic/larval cuticle,imaginal disc,embryo,spermathecum,spermathecal duct,tarsal segment,antennal sense organ,fat body/gonad primordium & parasegment 4twi.PGa,fat body/gonad primordium & parasegment 5twi.PGa,fat body/gonad primordium & parasegment 6twi.PGa,fat body/gonad primordium & parasegment 7twi.PGa,fat body/gonad primordium & parasegment 8twi.PGa,fat body/gonad primordium & parasegment 9twi.PGa,visceral mesoderm,precursor,embryonic/larval heart,fat body/gonad primordium & parasegment 6zen.Kr.PF,fat body/gonad primordium & parasegment 7zen.Kr.PF,fat body/gonad primordium & parasegment 8zen.Kr.PF,dorsal,costal cell,embryonic myoblast,embryonic/larval pericardial cell & embryonic myoblasthow-24B, twi.PG,midline glial cell,proximal,embryonic hindgut,dorsal triple row,medial triple row,ventral triple row,eye,adult head,commissure | embryonic stage,intersegmental nerve,segmental nerve,connective,RP neuron,MP1 neuron,fascicle,motor neuron & growth cone & embryo,presumptive embryonic/larval peripheral nervous system,neuromuscular junction | embryonic stage,midline neuronal primordium,UMI interneuron & axonsim.PS,VUM neuron & axonsim.PS,embryonic leading edge cell,mesothoracic tergum" FBgn0005062 fs(2)OW202 female sterile (2) OW202 http://flybase.org/reports/FBgn0005062 - gene - - - fs(2)OW202 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039756 CG9743 - http://flybase.org/reports/FBgn0039756 protein_coding_gene "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water ; GO:0016717 | inferred from electronic annotation with InterPro:IPR015876" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015876 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804 - "anon-WO0118547.264, CG9743" "IPR005804:Fatty acid desaturase domain, IPR015876:Acyl-CoA desaturase" CG9743 11-Aug-17 DroID_v2017_08 "Drer\scd, Drer\scdb" Scer\OLE1 "Cele\fat-5, Cele\fat-6, Cele\fat-7" Xtro\scd "Mmus\Scd1, Mmus\Scd2, Mmus\Scd4, Mmus\Scd3" "Hsap\SCD, Hsap\SCD5" FBgn0001986 Mtr4 Mtr4 helicase http://flybase.org/reports/FBgn0001986 "FBgn0027576, FBgn0027880, FBgn0032570, FBgn0041116" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR016438 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN002281432 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000003586 "neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN002281442 RNA catabolic process ; GO:0006401 | inferred from biological aspect of ancestor with PANTHER:PTN002281432 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013 defense response to virus ; GO:0051607 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG4152, cg4152, l.2.35Df, BG:DS09217.2, l(2)k14423, l(2)br44, br44, l(2)k14422, BcDNA:GH07290, lethal(2)35Df, Mtr4, l(2)35Df, L(2)35Df, dMtr4" "IPR025696:rRNA-processing arch domain, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR012961:ATP-dependent RNA helicase Ski2, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR016438:ATP-dependent RNA helicase Ski2, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4152 11-Aug-17 DroID_v2017_08 "Drer\skiv2l, Drer\skiv2l2" "Scer\SKI2, Scer\MTR4" Cele\mtr-4 "Xtro\skiv2l2, Xtro\skiv2l" "Mmus\Skiv2l2, Mmus\Skiv2l, Mmus\Ddx60" "Hsap\SKIV2L2, Hsap\SKIV2L, Hsap\DDX60L" "lethal,recessive,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective" "egg,macrochaeta,embryonic/larval neuroblast,ganglion mother cell" DRSC03560 E -0.699592539 0.797843571 0.337412133 -1.811410611 -0.062741721 0.669681342 FBgn0267105 CG45545 - http://flybase.org/reports/FBgn0267105 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45545 - CG45545 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016908 l(3)X27 lethal (3) X27 http://flybase.org/reports/FBgn0016908 - gene - - - "X27, l(3)X27" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030078 CG10970 - http://flybase.org/reports/FBgn0030078 protein_coding_gene acylphosphatase activity ; GO:0003998 | inferred from biological aspect of ancestor with PANTHER:PTN000003030 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:HL08157, CG10970" IPR001792:Acylphosphatase-like domain CG10970 11-Aug-17 DroID_v2017_08 "Drer\acyp2, Drer\acyp1" - - "Xtro\acyp1, Xtro\acyp2" "Mmus\Acyp2, Mmus\Acyp1" "Hsap\ACYP2, Hsap\ACYP1" viable FBgn0029103 anon-47Ba anon-47Ba http://flybase.org/reports/FBgn0029103 gene - - - "Fw RE, anon-47Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266894 CR45354 - http://flybase.org/reports/FBgn0266894 non_protein_coding_gene - - - CR45354 - CR45354 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083273 E(smoDN)2583 Enhancer of smoDN 2583 http://flybase.org/reports/FBgn0083273 gene - - - E(smoDN)2583 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263584 CR43609 - http://flybase.org/reports/FBgn0263584 non_protein_coding_gene - - - CR43609 - CR43609 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015331 abs abstrakt http://flybase.org/reports/FBgn0015331 "FBgn0010723, FBgn0011549, FBgn0062100" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR011545 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 helicase activity ; GO:0004386 | inferred from sequence or structural similarity" "sleep ; GO:0030431 | inferred from expression pattern mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "ABS, DmRH23, l(3)06863, l(3)06862, l(3)04505, l(3)00620, anon-WO0118547.315, CG14637, abs" "IPR001650:Helicase, C-terminal, IPR001878:Zinc finger, CCHC-type, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG14637 11-Aug-17 DroID_v2017_08 Drer\ddx41 Scer\PRP28 Cele\sacy-1 Xtro\ddx41 Mmus\Ddx41 Hsap\DDX41 embryonic stage

"lethal,recessive,heat sensitive,lethal - all die before end of larval stage,some die during third instar larval stage,wild-type,cell death defective" "retina,retina & axon,longitudinal connective,central nervous system,ommatidium,photoreceptor cell,ectopic,melanotic mass,Bolwig nerve,embryonic head,heat sensitive,nurse cell,follicle cell,pole cell,stage 5 embryo,ventral,embryonic neuroblast,neurite,spindle | heat sensitive,mitotic cell cycle | heat sensitive,egg chamber,oocyte nucleus,mesoderm,neuroblast,RP2 motor neuron,RP2sib neuron,A1-7 dorsal acute muscle 1" FBgn0015413 l(1)14Db lethal (1) 14Db http://flybase.org/reports/FBgn0015413 - gene - - - l(1)14Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266733 CR45206 - http://flybase.org/reports/FBgn0266733 non_protein_coding_gene - - - CR45206 - CR45206 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003906 tyb2 tiny bristle 2 http://flybase.org/reports/FBgn0003906 - gene - - - "tyb-2, tyb2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile" macrochaeta FBgn0013589 l(3)97De lethal (3) 97De http://flybase.org/reports/FBgn0013589 - gene - - - l(3)97De - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" FBgn0085632 CG41363 - http://flybase.org/reports/FBgn0085632 protein_coding_gene - - - CG41363 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019805 ifx iron felix http://flybase.org/reports/FBgn0019805 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ifx - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "wing vein,macrochaeta & wing,eye,ommatidium,wing" FBgn0067356 l(3)9358 lethal (3) 9358 http://flybase.org/reports/FBgn0067356 gene - - - l(3)9358 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043355 EP3015a EP3015a http://flybase.org/reports/FBgn0043355 gene - - - EP3015a - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "scutellar bristle,ectopic,tormogen cell,trichogen cell" FBgn0045827 CG13245 - http://flybase.org/reports/FBgn0045827 protein_coding_gene - - - "bs34a02.y1, BEST:GH09435, BEST:GH06096, BEST:GH21951, CG13245" - CG13245 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043471 kappaTry kappaTry http://flybase.org/reports/FBgn0043471 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SPH109, CG12388, kappaTry" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG12388 11-Aug-17 DroID_v2017_08 "Drer\LOC103908930, Drer\prss59.2, Drer\prss59.1, Drer\si:ch211-165b19.8" - Cele\try-1 - "Mmus\Klk11, Mmus\Klk1b21, Mmus\Prss54, Mmus\Klk1b11, Mmus\Klk1b16, Mmus\Mcpt8, Mmus\Klk1b22, Mmus\Klk9, Mmus\Klk10, Mmus\Prss55, Mmus\Egfbp2, Mmus\Klk1b24" "Hsap\KLK6, Hsap\KLK12, Hsap\KLK10, Hsap\KLK9, Hsap\KLK15, Hsap\AZU1, Hsap\CTSG, Hsap\PRSS57, Hsap\KLK2, Hsap\KLK3, Hsap\KLK1" FBgn0083276 E(smoDN)2576 Enhancer of smoDN 2576 http://flybase.org/reports/FBgn0083276 gene - - - E(smoDN)2576 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043039 l(2)42Be lethal (2) 42Be http://flybase.org/reports/FBgn0043039 gene - - - l(2)42Be - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061491 lsr loser http://flybase.org/reports/FBgn0061491 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available lsr - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0024931 Su(var)2-1001 Su(var)2-1001 http://flybase.org/reports/FBgn0024931 - gene - - - "Su-var(2)1001, Su(var)2-1001" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082356 HM274 HM274 http://flybase.org/reports/FBgn0082356 gene - - - HM274 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036702 CG6512 - http://flybase.org/reports/FBgn0036702 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000642, InterPro:IPR003959, InterPro:IPR003960, InterPro:IPR011546 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011546 metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity with UniProtKB:Q9Y4W6" lateral inhibition ; GO:0046331 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence or structural similarity with UniProtKB:Q9Y4W6 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011546 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9Y4W6 "DmCG6512, CG6512, AFG3L2" "IPR000642:Peptidase M41, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005936:Peptidase, FtsH, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011546:Peptidase M41, FtsH extracellular" CG6512 11-Aug-17 DroID_v2017_08 "Drer\yme1l1a, Drer\afg3l2, Drer\si:ch1073-174d20.2, Drer\spg7" "Scer\YME1, Scer\YTA12, Scer\AFG3" "Cele\ymel-1, Cele\spg-7, Cele\ppgn-1" "Xtro\afg3l2, Xtro\spg7, Xtro\afg3l1p" "Mmus\Yme1l1, Mmus\Afg3l2, Mmus\Afg3l1, Mmus\Spg7" "Hsap\AFG3L2, Hsap\SPG7, Hsap\YME1L1" "viable,visible" "chaeta,trichogen cell" FBgn0050482 CG30482 - http://flybase.org/reports/FBgn0050482 protein_coding_gene - - - CG30482 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary" FBgn0051404 CG31404 - http://flybase.org/reports/FBgn0051404 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3575, CG31404" IPR006623:Testicular haploid expressed repeat CG31404 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020346 anon-48Fa anon-48Fa http://flybase.org/reports/FBgn0020346 - gene - - - "543, anon-48Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264341 CG43797 - http://flybase.org/reports/FBgn0264341 protein_coding_gene - - - CG43797 "IPR016187:C-type lectin fold, IPR016186:C-type lectin-like/link domain, IPR001304:C-type lectin-like" CG43797 11-Aug-17 DroID_v2017_08 "Drer\LOC101886537, Drer\zmp:0000000924, Drer\si:dkey-187i8.2, Drer\si:ch211-133n4.7, Drer\illr2, Drer\LOC100007376, Drer\LOC101884526, Drer\zmp:0000000937, Drer\si:ch211-283g2.3, Drer\si:ch211-214k5.3, Drer\cd209, Drer\si:ch73-343l4.8, Drer\si:ch73-86n18.1, Drer\si:ch73-122g19.1, Drer\illr4, Drer\LOC100331140, Drer\si:ch211-232p21.6, Drer\si:ch73-361h17.1, Drer\illr1, Drer\si:dkey-61f9.1, Drer\illr3, Drer\si:dkey-61f9.2, Drer\zgc:174904, Drer\si:ch73-111e15.1, Drer\si:ch211-170d8.5, Drer\si:ch73-343l4.2, Drer\LOC101884413" - "Cele\clec-184, Cele\clec-160, Cele\clec-185, Cele\clec-198, Cele\clec-149, Cele\clec-202, Cele\C25G4.17, Cele\clec-199" - "Mmus\Clec4b2, Mmus\Cd209d, Mmus\Cd209g, Mmus\Cd207, Mmus\Asgr1, Mmus\Clec4a2, Mmus\Clec10a, Mmus\Mgl2, Mmus\Fcer2a, Mmus\Clec4n, Mmus\Clec4f, Mmus\Asgr2, Mmus\Cd209e, Mmus\Clec4a4, Mmus\Clec4g, Mmus\Clec4a3, Mmus\Clec4b1, Mmus\Cd209a, Mmus\Clec4a1, Mmus\Clec4d, Mmus\Cd209b, Mmus\Clec4e, Mmus\Cd209c, Mmus\Cd209f" "Hsap\CLEC4F, Hsap\CLEC6A, Hsap\CLEC4A, Hsap\CLEC4E, Hsap\ASGR1, Hsap\CD207, Hsap\CLEC4G, Hsap\CLEC4C, Hsap\CLEC17A, Hsap\CLEC4D, Hsap\CLEC10A, Hsap\ASGR2, Hsap\CLEC4M, Hsap\FCER2, Hsap\CD209" FBgn0030030 CG1636 - http://flybase.org/reports/FBgn0030030 protein_coding_gene - - - CG1636 - CG1636 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC18111 IK -0.275580997 1.856855587 0.230439509 0.322116667 2.007826609 0.859828206 FBgn0001334 l(1)1Ac lethal (1) 1Ac http://flybase.org/reports/FBgn0001334 FBgn0005413 gene - - - "lJ1, l(1)Ac, l(1)J1, J1, l(1)Jl, l(1)RF17, l(1)L61, l(1)G11, l(1)G1, l(1)A33, l(1)1Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0010130 l(1)tsW1 lethal (1) tsW1 http://flybase.org/reports/FBgn0010130 - gene - - - l(1)tsW1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0000281 Cec2 Cecropin 2 http://flybase.org/reports/FBgn0000281 - pseudogene_attribute - - - "CecPsi2, cec-Psi2, CR32924, CG32924, CR32934, CG32934, Cec2, Cec" - CR32934 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035260 CG7991 - http://flybase.org/reports/FBgn0035260 protein_coding_gene - - - CG7991 IPR001452:SH3 domain CG7991 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030499 CG11178 - http://flybase.org/reports/FBgn0030499 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell migration ; GO:0016477 | inferred from sequence or structural similarity with HGNC:28994 localization ; GO:0051179 | inferred from biological aspect of ancestor with PANTHER:PTN001256550 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001256550 recycling endosome ; GO:0055037 | inferred from sequence or structural similarity with HGNC:28994 CG11178 IPR018307:AVL9/DENND6 domain CG11178 11-Aug-17 DroID_v2017_08 Drer\avl9 Scer\AVL9 Cele\T26A5.6 Xtro\avl9 Mmus\Avl9 Hsap\AVL9 viable FBgn0037463 djl don juan like http://flybase.org/reports/FBgn0037463 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial derivative ; GO:0016007 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay sperm flagellum ; GO:0036126 | inferred from direct assay "dj like, CG1984, djl, dj-like, Don Juan-like" - CG1984 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,viable" FBgn0267126 CR45566 - http://flybase.org/reports/FBgn0267126 non_protein_coding_gene - - - CR45566 - CR45566 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069248 attP:Dps3 pseudo attP recognition site Dps3 http://flybase.org/reports/FBgn0069248 region - - - attP:Dps3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053340 CG33340 - http://flybase.org/reports/FBgn0053340 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13612, BEST:GH24664, BcDNA:AT31672, CG33340" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG33340 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0083308 E(smoDN)1438 Enhancer of smoDN 1438 http://flybase.org/reports/FBgn0083308 gene - - - E(smoDN)1438 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264409 FCE-B - http://flybase.org/reports/FBgn0264409 gene - - - FCE-B - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,somatic clone" FBgn0260042 circe circe http://flybase.org/reports/FBgn0260042 gene - - - circe - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0003881 tu(3)C4 tumor(3)C4 http://flybase.org/reports/FBgn0003881 - gene - - - "tu-C4, tu(3)C4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029643 CG14420 - http://flybase.org/reports/FBgn0029643 protein_coding_gene - - - CG14420 - CG14420 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary" DRSC25167 IEK 0.848598515 2.454644649 2.30721626 -0.767427185 2.414727452 -0.263012826 FBgn0000045 Act79B Actin 79B http://flybase.org/reports/FBgn0000045 - protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity actin filament ; GO:0005884 | inferred from sequence or structural similarity "Actin, 143060_f_at, actin, D, CG7478, mus79B, act 79B, act79B, Act79B, ArpF" "IPR020902:Actin/actin-like conserved site, IPR004000:Actin family, IPR004001:Actin, conserved site" CG7478 11-Aug-17 DroID_v2017_08 "Drer\zgc:86709, Drer\actc1a, Drer\actr1, Drer\acta1b, Drer\zgc:86725, Drer\si:ch211-241j12.3, Drer\actc1b, Drer\actb2, Drer\actr10, Drer\actb1, Drer\acta1a, Drer\si:ch73-187m15.4, Drer\acta2, Drer\ankrd52b" "Scer\ACT1, Scer\ARP6, Scer\ARP9, Scer\ARP1" "Cele\act-3, Cele\act-4, Cele\act-5, Cele\arp-1, Cele\act-1, Cele\act-2, Cele\arp-6" "Xtro\act3, Xtro\actg1, Xtro\ankrd52, Xtro\actb, Xtro\actc1, Xtro\actr1a, Xtro\acta2, Xtro\acta1, Xtro\actr10" "Mmus\Actrt1, Mmus\Actl7a, Mmus\Actg2, Mmus\Actl7b, Mmus\Actg1, Mmus\Actr1b, Mmus\Actl10, Mmus\Actl11, Mmus\Actr6, Mmus\Actr10, Mmus\Actb, Mmus\Actbl2, Mmus\Actr1a, Mmus\Actrt2, Mmus\Actl9, Mmus\Acta2, Mmus\Actrt3, Mmus\Actc1, Mmus\Acta1" "Hsap\ACTR1A, Hsap\ACTA2, Hsap\ACTBL2, Hsap\ACTB, Hsap\ACTG1, Hsap\POTEG, Hsap\ACTL9, Hsap\POTEF, Hsap\ACTG2, Hsap\ACTRT3, Hsap\POTEB, Hsap\ACTR10, Hsap\ACTC1, Hsap\POTED, Hsap\ACTRT1, Hsap\POTEH, Hsap\POTEJ, Hsap\POTEI, Hsap\POTEE, Hsap\ACTRT2, Hsap\ACTR6, Hsap\ACTL10, Hsap\POTEC, Hsap\ACTL8, Hsap\ACTA1, Hsap\ACTL7A, Hsap\POTEB2, Hsap\POTEA, Hsap\ACTL7B, Hsap\ACTR1B" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC11604 IEK -0.483749854 -2.954443186 0.425419399 -1.522535291 1.731784002 0.937078932 FBgn0263005 CG43313 - http://flybase.org/reports/FBgn0263005 protein_coding_gene acetylgalactosaminyltransferase activity ; GO:0008376 | inferred from electronic annotation with InterPro:IPR008428 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype Golgi cisterna membrane ; GO:0032580 | inferred from electronic annotation with InterPro:IPR008428 "CG43313, CG4351, CG12714, dCHPF" IPR008428:Chondroitin N-acetylgalactosaminyltransferase CG43313 11-Aug-17 DroID_v2017_08 "Drer\chpfa, Drer\chpf2, Drer\chpfb, Drer\LOC794660" - Cele\mig-22 "Xtro\chpf, Xtro\chpf2" "Mmus\Chpf2, Mmus\Chpf" "Hsap\CHPF2, Hsap\CHPF" FBgn0001866 l(1)X10 lethal (1) X10 http://flybase.org/reports/FBgn0001866 - gene - - - l(1)X10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0016713 Reg-18 Rhythmically expressed gene 18 http://flybase.org/reports/FBgn0016713 - gene - - - "Dreg-18, Reg-18" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | late , adult stage " adult head

FBgn0267648 pre-mod(mdg4)-G - http://flybase.org/reports/FBgn0267648 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-G, CG45986" "IPR007588:Zinc finger, FLYWCH-type" CG45986 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Flywch1, Mmus\Flywch2" - FBgn0067762 l(1)E-81 lethal (1) E-81 http://flybase.org/reports/FBgn0067762 gene - - - l(1)E-81 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002468 l(3)SG23 lethal (3) SG23 http://flybase.org/reports/FBgn0002468 - gene - - - "l(3)g49, l(3)SG23" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0034521 Mgat1 "Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1" http://flybase.org/reports/FBgn0034521 protein_coding_gene "acetylglucosaminyltransferase activity ; GO:0008375 | inferred from direct assay alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity ; GO:0003827 | inferred from direct assay" mushroom body development ; GO:0016319 | inferred from mutant phenotype brain segmentation ; GO:0035284 | inferred from mutant phenotype protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from direct assay encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype protein N-linked glycosylation ; GO:0006487 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype Golgi medial cisterna ; GO:0005797 | inferred from direct assay "dMGAT1, GlcNAc-TI, CG13431, MGAT1, Mgat1, GlcNAcT1" "IPR004139:Glycosyl transferase, family 13, IPR029044:Nucleotide-diphospho-sugar transferases" CG13431 11-Aug-17 DroID_v2017_08 "Drer\mgat1b, Drer\mgat1a" - "Cele\gly-14, Cele\gly-13, Cele\gly-12" Xtro\mgat1 Mmus\Mgat1 Hsap\MGAT1 "immune response defective,long lived,RU486 conditional,oxidative stress response defective,short lived,locomotor behavior defective,viable,conditional,hypoactive,recessive,male sterile,female fertile,female,male,neuroanatomy defective,dominant" mushroom body beta-lobe FBgn0017447 anon-14Ca anon-14Ca http://flybase.org/reports/FBgn0017447 - gene - - - anon-14Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050240 tRNA:Glu-TTC-1-2 transfer RNA:Glutamic acid-TTC 1-2 http://flybase.org/reports/FBgn0050240 tRNA_gene GAA codon-amino acid adaptor activity ; GO:0033459 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033459 cytosol ; GO:0005829 | inferred by curator from GO:0033459 "AE002787.trna43-GluTTC, tRNA:glu4:53A, tRNA:E4:53A, tRNA:E:TTC:AE002787-e, CR30240, tRNA:Glu, chr2R.trna26-GluTTC, tRNA:Glu-TTC-1-2, tRNA:CR30240, tRNA-Glu-TTC-1-2, GAA" - CR30240 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003671 tbr tracheae broken http://flybase.org/reports/FBgn0003671 - gene - - - "tb, tbr" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable embryonic/larval tracheal system FBgn0015877 anon-48Af anon-48Af http://flybase.org/reports/FBgn0015877 - gene - - - "VIII, anon-48Af" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267300 CR45736 - http://flybase.org/reports/FBgn0267300 non_protein_coding_gene - - - CR45736 - CR45736 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265744 CR44551 - http://flybase.org/reports/FBgn0265744 non_protein_coding_gene - - - CR44551 - CR44551 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062627 Mod(var)1044 Mod(var)1044 http://flybase.org/reports/FBgn0062627 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1044, Mod(var)1044" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0039577 CG12516 - http://flybase.org/reports/FBgn0039577 protein_coding_gene - - - CG12516 IPR009961:Protein of unknown function DUF1487 CG12516 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266778 CR45243 - http://flybase.org/reports/FBgn0266778 non_protein_coding_gene - - - CR45243 - CR45243 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267933 CR46213 - http://flybase.org/reports/FBgn0267933 non_protein_coding_gene - - - "CR46213, lincRNA.565" - CR46213 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015007 Abl::Mmus\Abl Abl::Mmus\Abl http://flybase.org/reports/FBgn0015007 - engineered_fusion_gene - - - "Abl::Mus\Abl, Abl::Mmus\Abl" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266212 CR44907 - http://flybase.org/reports/FBgn0266212 non_protein_coding_gene - - - CR44907 - CR44907 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035385 FMRFaR FMRFamide Receptor http://flybase.org/reports/FBgn0035385 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from physical interaction with FMRFa peptide receptor activity ; GO:0001653 | inferred from direct assay G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay positive regulation of cytosolic calcium ion concentration ; GO:0007204 | inferred from direct assay larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model behavioral defense response ; GO:0002209 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG2114, FMRFaR, DrmFMRFa-R, FR, Dm FMRFa-R, FMRFa-R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM, IPR019427:7TM GPCR, serpentine receptor class w (Srw)" CG2114 11-Aug-17 DroID_v2017_08 "Drer\valopa, Drer\gpr35.1, Drer\s1pr2, Drer\gpr142" - "Cele\sri-50, Cele\sri-71, Cele\srsx-9, Cele\F56A11.4, Cele\sri-54, Cele\sri-24, Cele\R11F4.2, Cele\frpr-10, Cele\frpr-4, Cele\Y37E11AL.1, Cele\sri-1, Cele\sri-25, Cele\sri-29, Cele\srh-79, Cele\D1079.1, Cele\sri-7, Cele\sri-34, Cele\sri-11, Cele\M01G12.6, Cele\frpr-5, Cele\Y27F2A.10, Cele\B0034.5, Cele\sri-73, Cele\srh-231, Cele\frpr-9, Cele\sri-12, Cele\frpr-18, Cele\Y40C5A.4, Cele\sri-20, Cele\Y41D4B.24, Cele\sri-43, Cele\sri-32, Cele\sri-14, Cele\sri-74, Cele\F32D8.10, Cele\frpr-7, Cele\sri-37, Cele\sri-31, Cele\sri-21, Cele\frpr-8, Cele\sri-53, Cele\sri-46, Cele\sri-61, Cele\frpr-6, Cele\sri-63, Cele\sri-27, Cele\frpr-2, Cele\frpr-12, Cele\E04D5.2, Cele\sri-18, Cele\sri-4, Cele\sri-42, Cele\B0334.6, Cele\ZK105.8, Cele\sri-33, Cele\sri-66, Cele\sri-26, Cele\Y27F2A.11, Cele\sri-47, Cele\srh-257, Cele\frpr-16, Cele\sri-10, Cele\frpr-19, Cele\sri-62, Cele\frpr-1, Cele\sri-28, Cele\sri-67, Cele\frpr-13, Cele\daf-37, Cele\sri-6, Cele\sri-70, Cele\sri-30, Cele\frpr-17, Cele\sri-51, Cele\T11F9.1, Cele\F15A8.4, Cele\sri-45, Cele\sri-36, Cele\sri-57, Cele\srsx-11, Cele\C54D10.5, Cele\sri-77, Cele\srh-258, Cele\sri-40, Cele\sri-48, Cele\sri-13, Cele\frpr-14, Cele\sri-39, Cele\F20A1.2, Cele\C09F12.3, Cele\frpr-11, Cele\sri-16, Cele\sri-5, Cele\sri-69, Cele\C39B10.1, Cele\sri-78, Cele\sri-15, Cele\F57A8.4, Cele\frpr-3, Cele\sri-65, Cele\frpr-15, Cele\sri-60, Cele\sri-17, Cele\sri-19, Cele\ZK1307.7, Cele\sri-38, Cele\srsx-18" - "Mmus\Olfr659, Mmus\Olfr584, Mmus\Gpr142, Mmus\Olfr1179, Mmus\Olfr582, Mmus\Gpr139, Mmus\Cysltr2" "Hsap\GPR139, Hsap\OR52K1, Hsap\P2RY10" "viable,fertile" FBgn0086049 snoRNA:Me28S-U3344a - http://flybase.org/reports/FBgn0086049 snoRNA_gene - - - "snoRNA:Me28S-U3344a, Me28S-Um3344a, MeS8SU3344a, CR34678, mg28S-3344" - CR34678 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259227 CG42327 - http://flybase.org/reports/FBgn0259227 protein_coding_gene "protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR000242, InterPro:IPR016130 protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement" protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000242 protein dephosphorylation ; GO:0006470 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CG42327, CG18479, anon-WO0118547.710, CG14713, CG14714" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR003595:Protein-tyrosine phosphatase, catalytic" CG42327 11-Aug-17 DroID_v2017_08 "Drer\ptpn5, Drer\ptpn1, Drer\ptpn2a, Drer\ca16c, Drer\ptpn22, Drer\ptprc, Drer\ptprz1b, Drer\ptpn6, Drer\ptprga, Drer\ptpn18, Drer\ptpn11b, Drer\ptprr, Drer\ptpn2b, Drer\ca16b" "Scer\PTP1, Scer\PTP3, Scer\PTP2" "Cele\F36H12.10, Cele\F10G8.1, Cele\M04G7.2, Cele\C55B7.3, Cele\B0207.1, Cele\F36H1.3, Cele\T22C1.8, Cele\ZK616.65, Cele\ZK484.7, Cele\H06I04.5, Cele\C33H5.16, Cele\ZK616.8, Cele\F47B3.1, Cele\Y39A3A.4, Cele\C02B10.6, Cele\F47B3.7, Cele\K07F5.8, Cele\Y48G9A.9, Cele\T27A3.5, Cele\ZK354.8, Cele\C17H12.3, Cele\F47B3.6" "Xtro\ptprr, Xtro\ptpn2, Xtro\ptprz1, Xtro\ptpn1, Xtro\ptpn12, Xtro\ptpn23, Xtro\ptpn22" "Mmus\Ptpn22, Mmus\Ptpn7, Mmus\Ptprr, Mmus\Ptpn12, Mmus\Ptpn20, Mmus\Ptpn1, Mmus\Ptpn5, Mmus\Ptpn2, Mmus\Ptpn18, Mmus\Ptpn23, Mmus\Ptpn6, Mmus\Ptprg, Mmus\Ptprc" "Hsap\PTPRC, Hsap\PTPN23, Hsap\PTPN2, Hsap\PTPN7, Hsap\PTPRG, Hsap\PTPN12, Hsap\PTPN1, Hsap\PTPN6, Hsap\PTPN22, Hsap\PTPRR, Hsap\PTPN5, Hsap\PTPN18, Hsap\PTPN20" DRSC14937 E -0.701053665 0.902262282 4.131896222 0.299274902 0.971734764 -0.102033293 FBgn0267140 CR45580 - http://flybase.org/reports/FBgn0267140 non_protein_coding_gene - - - CR45580 - CR45580 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050093 COX6AL Cytochrome c oxidase subunit 6A-like http://flybase.org/reports/FBgn0050093 protein_coding_gene enzyme regulator activity ; GO:0030234 | inferred from biological aspect of ancestor with PANTHER:PTN000161400 cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000161400 "aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000161400 aerobic respiration ; GO:0009060 | inferred from sequence or structural similarity with SGD:S000003159 mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000161400" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000161401 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000003159 "NEST:bs02a12, CG30093, COXD, COXE, COX6AL" "IPR001349:Cytochrome c oxidase, subunit VIa" CG30093 11-Aug-17 DroID_v2017_08 "Drer\cox6a2, Drer\cox6a1" Scer\COX13 Cele\tag-174 "Xtro\cox6a2, Xtro\cox6a1" "Mmus\Cox6a1, Mmus\Cox6a2" "Hsap\COX6A2, Hsap\COX6A1" viable FBgn0067342 l(3)L3F lethal (3) L3F http://flybase.org/reports/FBgn0067342 gene - - - l(3)L3F - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027281 l(1)G0191 lethal (1) G0191 http://flybase.org/reports/FBgn0027281 - gene - - - l(1)G0191 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0259414 EP-17 - http://flybase.org/reports/FBgn0259414 gene - - - EP-17 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0038271 UQCR-C1 Ubiquinol-cytochrome c reductase core protein 1 http://flybase.org/reports/FBgn0038271 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000220169 metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000220169 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:P31930 metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity with UniProtKB:O75439 "protein processing ; GO:0016485 | inferred from sequence or structural similarity with UniProtKB:O75439 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000220240 cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000220240 protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000220169 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:P31930" mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN000220240 mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:P31930 microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:O75439 "CG3731, CG 3731, UCR1, MPPB, UQCR-C1, Mpp" "IPR001431:Peptidase M16, zinc-binding site, IPR007863:Peptidase M16, C-terminal, IPR011765:Peptidase M16, N-terminal, IPR011249:Metalloenzyme, LuxS/M16 peptidase-like" CG3731 11-Aug-17 DroID_v2017_08 "Drer\uqcrc1, Drer\pmpcb" "Scer\QCR2, Scer\COR1, Scer\MAS1" "Cele\ucr-1, Cele\mppb-1" "Xtro\uqcrc1, Xtro\pmpcb" "Mmus\Uqcrc1, Mmus\Pmpcb" "Hsap\UQCRC1, Hsap\PMPCB" "viable,fertile,visible,lethal" mesothoracic tergum DRSC15508 K -0.645110582 -0.598806369 -1.21188733 -1.255991359 1.78948517 -0.095624857 FBgn0024664 l(2)k06020 lethal (2) k06020 http://flybase.org/reports/FBgn0024664 - gene - - - "60/20, l(2)k06020" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024986 CG3719 - http://flybase.org/reports/FBgn0024986 "FBgn0029575, FBgn0063169" protein_coding_gene disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence or structural similarity with UniProtKB:Q99757 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR005746, InterPro:IPR013766" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q99757 "EG:132E8.3, BcDNA:LD03613, CG3719" "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain" CG3719 11-Aug-17 DroID_v2017_08 Drer\txn2 "Scer\RIM1, Scer\WHI3" "Cele\trx-2, Cele\gei-4" Xtro\txn2 "Mmus\Txn2, Mmus\Smad1" "Hsap\SMAD1, Hsap\ZNF396, Hsap\TXN2" "viable,fertile,lethal,recessive" FBgn0086070 snoRNA:Or-CD11c - http://flybase.org/reports/FBgn0086070 snoRNA_gene - - - "snoRNA:Or-CD11c, orphan CD11c, CR34699" - CR34699 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060917 l(3)S042610 lethal (3) S042610 http://flybase.org/reports/FBgn0060917 gene - - - "0426/10, l(3)S042610" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0021955 l(2)k10237 lethal (2) k10237 http://flybase.org/reports/FBgn0021955 - gene - - - l(2)k10237 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015011 AhcyL2 Adenosylhomocysteinase like 2 http://flybase.org/reports/FBgn0015011 - protein_coding_gene "adenosylhomocysteinase activity ; GO:0004013 | inferred from electronic annotation with InterPro:IPR000043, InterPro:IPR020082" "one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR000043, InterPro:IPR020082 S-adenosylmethionine cycle ; GO:0033353 | inferred from biological aspect of ancestor with PANTHER:PTN000602759" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000602759 "AHCY, pH200, S-AHCY, CG8956, Ahcy89E, dAhcyL2, AhcyL2" "IPR000043:Adenosylhomocysteinase-like, IPR015878:S-adenosyl-L-homocysteine hydrolase, NAD binding domain, IPR016040:NAD(P)-binding domain, IPR020082:S-adenosyl-L-homocysteine hydrolase, conserved site" CG8956 11-Aug-17 DroID_v2017_08 "Drer\ahcyl1, Drer\zgc:158222, Drer\ahcy, Drer\ahcyl2" Scer\SAH1 Cele\ahcy-1 "Xtro\ahcyl2, Xtro\ahcy, Xtro\ahcyl1" "Mmus\Ahcy, Mmus\Ahcyl2, Mmus\Gm4737, Mmus\Ahcyl1" "Hsap\AHCY, Hsap\AHCYL1, Hsap\AHCYL2" embryonic stage " embryonic/larval midgut

, somatic mesoderm

" viable FBgn0014193 hty hypersprouty http://flybase.org/reports/FBgn0014193 - gene - - - hty - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263490 mld molting defective http://flybase.org/reports/FBgn0263490 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "mld, CG34100, CG13620, CG33343, CG9469, CG31312, Mld, l(3)3[DTS], DTS-3, L(3)3[DTS], l(3)DTS3" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG34100 11-Aug-17 DroID_v2017_08 "Drer\gtf3aa, Drer\LOC100330321, Drer\LOC568955, Drer\si:ch73-347e22.4" Scer\PZF1 "Cele\F21A9.2, Cele\pqm-1, Cele\F10B5.3" Xtro\znf250 Mmus\Gtf3a Hsap\GTF3A FBgn0044045 J3220 J3220 http://flybase.org/reports/FBgn0044045 gene - - - J3220 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266768 CR45233 - http://flybase.org/reports/FBgn0266768 non_protein_coding_gene - - - CR45233 - CR45233 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262269 mir-955 mir-955 stem loop http://flybase.org/reports/FBgn0262269 miRNA_gene - - - "mir-955, CR42976, miR-955" - CR42976 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0064243 EP3617 EP3617 http://flybase.org/reports/FBgn0064243 gene - - - EP3617 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0266667 Exo70 Exocyst 70 http://flybase.org/reports/FBgn0266667 protein_coding_gene "beta-catenin binding ; GO:0008013 | inferred from physical interaction with arm phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from sequence or structural similarity with SGD:S000003621" exocytosis ; GO:0006887 | inferred from electronic annotation with InterPro:IPR004140 synaptic vesicle targeting ; GO:0016080 | non-traceable author statement synaptic vesicle docking ; GO:0016081 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity exocyst ; GO:0000145 | inferred from electronic annotation with InterPro:IPR004140 exocyst ; GO:0000145 | inferred from sequence or structural similarity exocyst ; GO:0000145 | non-traceable author statement "exo70, Exo70, CG7127, Exo70p" "IPR004140:Exocyst complex component Exo70, IPR016159:Cullin repeat-like-containing domain" CG7127 11-Aug-17 DroID_v2017_08 Drer\exoc7 Scer\EXO70 Cele\exoc-7 Xtro\exoc7 Mmus\Exoc7 Hsap\EXOC7 FBgn0010033 E(var)21 E(var)21 http://flybase.org/reports/FBgn0010033 - gene - - - E(var)21 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003669 tbd tiny bristloid http://flybase.org/reports/FBgn0003669 - gene - - - tbd - - 11-Aug-17 DroID_v2017_08 - - - - - - "small body,viable,fertile" macrochaeta FBgn0060568 l(3)S096507b lethal (3) S096507b http://flybase.org/reports/FBgn0060568 gene - - - "0965/07, l(3)S096507b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0037609 CG9773 - http://flybase.org/reports/FBgn0037609 protein_coding_gene - transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000303504 integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000303504 CG9773 IPR007881:UNC-50 CG9773 11-Aug-17 DroID_v2017_08 Drer\unc50 Scer\GMH1 Cele\unc-50 Xtro\unc50 Mmus\Unc50 Hsap\UNC50 FBgn0005320 ney narrow eye http://flybase.org/reports/FBgn0005320 - gene - - - ney - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile" eye FBgn0034153 Acp53C14b Accessory gland protein 53C14b http://flybase.org/reports/FBgn0034153 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG15616, Acp53C14b, Acp53Cb, Acp53" IPR009392:Drosophila ACP53EA CG15616 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0034833 CG13539 - http://flybase.org/reports/FBgn0034833 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13539 IPR009961:Protein of unknown function DUF1487 CG13539 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065329 l(2)SH1890 lethal (2) SH1890 http://flybase.org/reports/FBgn0065329 gene - - - "l(2)SH1890, l(2)SH2 1890" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001450 l(1)7Dd lethal (1) 7Dd http://flybase.org/reports/FBgn0001450 - gene - - - l(1)7Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0265195 veg vegetable http://flybase.org/reports/FBgn0265195 gene - - - "CG6657, veg, l(2)k01206" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal" "presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,fascicle,presumptive embryonic/larval central nervous system" FBgn0004114 Su(var)303 Suppressor of variegation 303 http://flybase.org/reports/FBgn0004114 - gene - - - Su(var)303 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004211 l(3)84Ei lethal (3) 84Ei http://flybase.org/reports/FBgn0004211 - gene - - - l(3)84Ei - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002642 Malf Malformed http://flybase.org/reports/FBgn0002642 - gene - - - "Mal, Malf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,dominant" "eye,ommatidium" FBgn0262542 CR43096 - http://flybase.org/reports/FBgn0262542 pseudogene_attribute - - - CR43096 - CR43096 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028320 l(1)G0343 lethal (1) G0343 http://flybase.org/reports/FBgn0028320 gene - - - l(1)G0343 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002199 l(3)67Ac lethal (3) 67Ac http://flybase.org/reports/FBgn0002199 - gene - - - l(3)67Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,recessive,some die during immature adult stage" "eye,wing" FBgn0031741 CG11034 - http://flybase.org/reports/FBgn0031741 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR001375 dipeptidyl-peptidase activity ; GO:0008239 | inferred from direct assay "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001375, InterPro:IPR002469" - CG11034 "IPR002469:Dipeptidylpeptidase IV, N-terminal domain, IPR029058:Alpha/Beta hydrolase fold, IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain" CG11034 11-Aug-17 DroID_v2017_08 "Drer\fap, Drer\zgc:136971, Drer\LOC101883320, Drer\dpp6b, Drer\dpp6a, Drer\LOC101886435, Drer\apeh, Drer\dpp4" "Scer\STE13, Scer\DAP2" "Cele\dpf-2, Cele\dpf-1" "Xtro\apeh, Xtro\dpp6, Xtro\dpp4, Xtro\dpp10" "Mmus\Dpp10, Mmus\Dpp6, Mmus\Fap, Mmus\Dpp4, Mmus\Apeh" "Hsap\DPP4, Hsap\DPP10, Hsap\DPP6, Hsap\FAP, Hsap\APEH" viable DRSC02122 K -0.071220947 0.43645371 -0.297776783 0.530207358 1.630051079 0.054299364 FBgn0000886 fs(1)M84 female sterile (1) M84 http://flybase.org/reports/FBgn0000886 - gene - - - fs(1)M84 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0022040 l(2)k08320 lethal (2) k08320 http://flybase.org/reports/FBgn0022040 - gene - - - l(2)k08320 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036715 Cad74A Cadherin 74A http://flybase.org/reports/FBgn0036715 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Cad74A calcium ion binding ; GO:0005509 | inferred from direct assay dorsal appendage formation ; GO:0046843 | inferred from direct assay calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from direct assay homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from direct assay microvillus ; GO:0005902 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "CG6445, DCad74B, Cad74B, CT20086, Cad74A, cad74A" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site" CG6445 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-22o22.2, Drer\fat1b, Drer\dchs1b, Drer\fat2, Drer\cdh23, Drer\cdh17, Drer\dchs1a, Drer\cdh16, Drer\cdhr5b, Drer\fat1a, Drer\cdhr2, Drer\si:ch211-186j3.6, Drer\cdhr5a, Drer\cdh13, Drer\fat3a" - "Cele\cdh-3, Cele\cdh-8, Cele\cdh-9, Cele\fmi-1" "Xtro\dchs2, Xtro\fat1, Xtro\fat4" "Mmus\Fat1, Mmus\Fat3, Mmus\Cdhr1, Mmus\Cdhr2, Mmus\Cdh23, Mmus\Cdh17, Mmus\Cdh13, Mmus\Fat2, Mmus\Dchs1" "Hsap\CDHR2, Hsap\CDHR1, Hsap\DCHS2, Hsap\FAT2, Hsap\FAT1, Hsap\CDH13, Hsap\FAT3, Hsap\CDH23, Hsap\DLK2, Hsap\FAT4, Hsap\CDH17, Hsap\DCHS1" "viable,fertile,body color defective" "dorsal appendage,follicle cell,egg chamber,mesothoracic tergum" FBgn0002073 l(2)49Fb lethal (2) 49Fb http://flybase.org/reports/FBgn0002073 FBgn0002076 gene - - - "vr8, vr4, vr-8, vr-4, l(2)vr4, l(2)vr8, l(2)49Fe, l(2)49Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,non-suppressor of variegation,dominant,viable" FBgn0020855 fs(2)C10 fs(2)C10 http://flybase.org/reports/FBgn0020855 - gene - - - "2-C10, fs(2)C10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,female sterile" FBgn0066331 prx Pavlov's Rex http://flybase.org/reports/FBgn0066331 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Rex, prx, rex" - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0086423 l(3)CHg lethal (3) CHg http://flybase.org/reports/FBgn0086423 gene - - - l(3)CHg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261296 GJ20676 - http://flybase.org/reports/FBgn0261296 protein_coding_gene - - - "GJ20676, HSF" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267793 CR45232 - http://flybase.org/reports/FBgn0267793 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR45232, CG43265, mdcds_12606" - CR45232 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262392 mir-1004 mir-1004 stem loop http://flybase.org/reports/FBgn0262392 miRNA_gene - - - "dme-mir-1004, miR-1004, mir-1004, CR42926" - CR42926 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037298 CG2604 - http://flybase.org/reports/FBgn0037298 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005097 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005097 chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp wing disc development ; GO:0035220 | inferred from genetic interaction with Bx lipid particle ; GO:0005811 | inferred from direct assay "CT40966, CG2604" "IPR005097:Saccharopine dehydrogenase, NADP binding domain, IPR016040:NAD(P)-binding domain" CG2604 11-Aug-17 DroID_v2017_08 "Drer\sccpdhb, Drer\ruvbl2, Drer\sccpdha, Drer\ruvbl1, Drer\zgc:174379" - "Cele\Y50D4B.2, Cele\ruvb-1, Cele\F22F7.2, Cele\ruvb-2, Cele\ldp-1" "Xtro\ruvbl1, Xtro\LOC100490002, Xtro\ruvbl2, Xtro\sccpdh" "Mmus\Ruvbl1, Mmus\Ruvbl2, Mmus\Sccpdh" "Hsap\RUVBL1, Hsap\SCCPDH, Hsap\RUVBL2" viable "wing vein,ectopic" DRSC29919 K -0.200320031 -0.703547224 -0.168330664 0.069099755 -1.234252589 2.70731242 FBgn0266244 CR44939 - http://flybase.org/reports/FBgn0266244 non_protein_coding_gene - - - CR44939 - CR44939 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052626 AMPdeam AMP deaminase http://flybase.org/reports/FBgn0052626 protein_coding_gene AMP deaminase activity ; GO:0003876 | inferred from electronic annotation with InterPro:IPR006329 protein binding ; GO:0005515 | inferred from physical interaction with egg IMP salvage ; GO:0032264 | inferred from electronic annotation with InterPro:IPR006329 cytosol ; GO:0005829 | inferred from direct assay "CG11058, CG15762, CG11065, CG32626, AMPdeam, AMP deam" "IPR001365:Adenosine/AMP deaminase domain, IPR006329:AMP deaminase, IPR006650:Adenosine/AMP deaminase active site, IPR029749:AMP deaminase 2, IPR032466:Metal-dependent hydrolase" CG32626 11-Aug-17 DroID_v2017_08 "Drer\ampd2a, Drer\ampd2b, Drer\ampd1, Drer\ampd3a, Drer\ampd3b" "Scer\AMD1, Scer\YBR284W, Scer\YJL070C" Cele\ampd-1 "Xtro\ampd2, Xtro\ampd1, Xtro\ampd3" "Mmus\Ampd1, Mmus\Ampd2, Mmus\Ampd3" "Hsap\AMPD3, Hsap\AMPD2, Hsap\AMPD1" "partially lethal - majority die,some die during pupal stage,viable" DRSC19368 I 0.596557059 3.058047761 1.002544423 -0.715926298 -1.109213934 -0.085549501 FBgn0023065 l(1)20Bd lethal (1) 20Bd http://flybase.org/reports/FBgn0023065 - gene - - - "C2/5.3, l(1)20Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053446 5SrRNA:CR33446 5SrRNA:CR33446 http://flybase.org/reports/FBgn0053446 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33446, 5SrRNA:CR33446" - CR33446 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052176 CG32176 - http://flybase.org/reports/FBgn0052176 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG13730, CG13729, CG32176" - CG32176 11-Aug-17 DroID_v2017_08 "Drer\caap1, Drer\hdgfrp2" - Cele\F15D4.2 Xtro\caap1 Mmus\Caap1 Hsap\CAAP1 "viable,fertile,planar polarity defective" FBgn0062255 Su(Sd)2a-1 Suppressor of SD 2a-1 http://flybase.org/reports/FBgn0062255 gene - - - "Su(SD)[2a-1], Su(Sd)2a-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259589 B0193 - http://flybase.org/reports/FBgn0259589 gene - - - B0193 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,antennal segment,arista,tarsal segment" FBgn0084970 gloin gloin http://flybase.org/reports/FBgn0084970 gene - "primary branching, open tracheal system ; GO:0007428 | inferred from mutant phenotype" - "glo, gloin" - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic/larval tracheal system,visceral branch primordium,dorsal trunk primordium,tracheal system" FBgn0262539 CG43093 - http://flybase.org/reports/FBgn0262539 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43093 - CG43093 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037369 CG2100 - http://flybase.org/reports/FBgn0037369 protein_coding_gene nucleotidyltransferase activity ; GO:0016779 | inferred from electronic annotation with InterPro:IPR002646 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002646 RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR002646 neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG2100 "IPR002646:Poly A polymerase, head domain, IPR032828:tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain" CG2100 11-Aug-17 DroID_v2017_08 Drer\trnt1 Scer\CCA1 Cele\hpo-31 Xtro\trnt1 Mmus\Trnt1 Hsap\TRNT1 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell FBgn0259615 B1515 - http://flybase.org/reports/FBgn0259615 gene - - - B1515 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030459 CG12723 - http://flybase.org/reports/FBgn0030459 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12723 - CG12723 11-Aug-17 DroID_v2017_08 Drer\marco - - - Mmus\Marco Hsap\MARCO viable FBgn0259236 comm3 comm3 http://flybase.org/reports/FBgn0259236 protein_coding_gene - axon guidance ; GO:0007411 | inferred from electronic annotation with InterPro:IPR031878 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern - "CG42334, CG33209, CG13448, CG13447, comm3, CG13446" IPR031878:Commissureless CG42334 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031693 Cyp4ac1 Cyp4ac1 http://flybase.org/reports/FBgn0031693 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CG14032, 4ac1, Cyp4ac1, cyp4ac1, CYP4ac1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG14032 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp46a1.4, Drer\cyp4v8, Drer\cyp4t8, Drer\cyp4f3, Drer\cyp46a1.2, Drer\cyp26c1, Drer\cyp26b1, Drer\cyp4v7, Drer\cyp19a1b, Drer\cyp19a1a, Drer\cyp3c4, Drer\cyp46a1.1, Drer\LOC100329425, Drer\cyp26a1, Drer\cyp46a1.3, Drer\cyp20a1, Drer\cyp3c2" "Scer\ERG5, Scer\DIT2" "Cele\cyp-31A5, Cele\cyp-25A1, Cele\cyp-29A2, Cele\cyp-37A1, Cele\cyp-42A1, Cele\cyp-13A8, Cele\cyp-13A5, Cele\cyp-25A3, Cele\cyp-37B1, Cele\cyp-13A1, Cele\cyp-32A1, Cele\cyp-13A11, Cele\cyp-13A12, Cele\cyp-25A2, Cele\cyp-13A10, Cele\cyp-29A4, Cele\cyp-13A3, Cele\cyp-13A7, Cele\cyp-29A3, Cele\cyp-32B1, Cele\cyp-31A3, Cele\cyp-31A2, Cele\cyp-25A4, Cele\cyp-13A4" "Xtro\LOC100487918, Xtro\cyp26b1, Xtro\cyp4v2, Xtro\cyp26c1, Xtro\cyp4f22, Xtro\LOC100488227, Xtro\cyp4b1.2, Xtro\cyp4b1, Xtro\cyp19a1, Xtro\mgc108213, Xtro\cyp4f2, Xtro\cyp20a1, Xtro\cyp26a1" "Mmus\Cyp20a1, Mmus\Cyp26a1, Mmus\Cyp4a10, Mmus\Cyp4a31, Mmus\Cyp4x1, Mmus\Cyp4f15, Mmus\Cyp3a44, Mmus\Cyp26c1, Mmus\Cyp4f13, Mmus\Cyp4f40, Mmus\Cyp3a57, Mmus\Cyp4a32, Mmus\Cyp3a41b, Mmus\Cyp26b1, Mmus\Cyp3a16, Mmus\Cyp4a29, Mmus\Cyp4f18, Mmus\Cyp3a25, Mmus\Cyp4a30b, Mmus\Cyp19a1, Mmus\Cyp4a14, Mmus\Cyp3a13, Mmus\Cyp46a1, Mmus\Cyp3a41a, Mmus\Cyp4f37, Mmus\Cyp4f14, Mmus\Cyp3a11, Mmus\Cyp4f17, Mmus\Cyp4f39, Mmus\Cyp4f16, Mmus\Cyp3a59, Mmus\Cyp4a12b, Mmus\Cyp4b1, Mmus\Cyp4v3, Mmus\Cyp4a12a" "Hsap\CYP4B1, Hsap\CYP4F12, Hsap\CYP26A1, Hsap\CYP20A1, Hsap\CYP3A4, Hsap\CYP4A11, Hsap\CYP4Z1, Hsap\CYP26B1, Hsap\CYP4F3, Hsap\CYP4F8, Hsap\CYP3A7, Hsap\CYP4F2, Hsap\CYP46A1, Hsap\CYP4V2, Hsap\CYP3A5, Hsap\CYP4X1, Hsap\CYP3A43, Hsap\CYP26C1, Hsap\CYP4A22, Hsap\CYP4F11, Hsap\CYP4F22, Hsap\CYP19A1" FBgn0001127 gp gap http://flybase.org/reports/FBgn0001127 - gene - - - gp - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein L4 FBgn0034435 fest wurstfest http://flybase.org/reports/FBgn0034435 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern spindle assembly involved in male meiosis I ; GO:0007054 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "fest, CG9975" - CG9975 11-Aug-17 DroID_v2017_08 - - Cele\C44B9.2 - - - "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval neuroblast FBgn0034975 enok enoki mushroom http://flybase.org/reports/FBgn0034975 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR005818 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 histone acetyltransferase activity (H3-K23 specific) ; GO:0043994 | inferred from direct assay "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818 regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002717 negative regulation of stem cell differentiation ; GO:2000737 | inferred from mutant phenotype inferred from genetic interaction with bru1 mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from mutant phenotype neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype histone H3 acetylation ; GO:0043966 | inferred from direct assay dorsal/ventral axon guidance ; GO:0033563 | inferred from mutant phenotype" nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818 MOZ/MORF histone acetyltransferase complex ; GO:0070776 | inferred from direct assay "dmHAG406, anon-WO0200864.2, CG11290, rot, S1, anon-WO0200864.1, anon-60Ba, enok, KAT6, Enok, Cg11290" "IPR001965:Zinc finger, PHD-type, IPR002717:Histone acetyltransferase domain, MYST-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005818:Linker histone H1/H5, domain H15, IPR016181:Acyl-CoA N-acyltransferase, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11290 11-Aug-17 DroID_v2017_08 "Drer\kat7b, Drer\kat5a, Drer\kat7a, Drer\kat8, Drer\kat5b, Drer\kat6a, Drer\kat6b" "Scer\ESA1, Scer\SAS2, Scer\SAS3" "Cele\mys-4, Cele\lsy-12" "Xtro\kat7, Xtro\xnf7, Xtro\kat5, Xtro\trim69.1, Xtro\kat8" "Mmus\Kat6b, Mmus\Kat8, Mmus\Kat7, Mmus\Kat6a, Mmus\Kat5" "Hsap\KAT7, Hsap\KAT5, Hsap\KAT8, Hsap\KAT6B, Hsap\KAT6A" "neuroanatomy defective,somatic clone,size defective,female semi-sterile,germline clone,lethal,recessive,viable,visible" "female germline stem cell,progressive,heat sensitive,germarium cap cell,germline clone,axon | somatic clone | third instar larval stage,somatic clone,adult mushroom body,mesothoracic tergum" FBgn0029018 l(3)77CDg lethal (3) 77CDg http://flybase.org/reports/FBgn0029018 gene - - - l(3)77CDg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015021 Chap50 Chromosome-associated protein 50kD http://flybase.org/reports/FBgn0015021 - gene chromatin binding ; GO:0003682 | inferred from direct assay - - Chap50 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037766 Teh1 tipE homolog 1 http://flybase.org/reports/FBgn0037766 protein_coding_gene sodium channel regulator activity ; GO:0017080 | inferred from direct assay regulation of sodium ion transport ; GO:0002028 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG12806, TEH1, Teh1" IPR031578:Na+ channel auxiliary subunit TipE CG12806 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005664 Crys Crystallin http://flybase.org/reports/FBgn0005664 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of eye lens ; GO:0005212 | inferred from direct assay calcium ion binding ; GO:0005509 | inferred from direct assay visual perception ; GO:0007601 | inferred by curator from GO:0005212 compound eye corneal lens development ; GO:0048058 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from direct assay "dcy, CG16963, DmelCry, Crys, Cry, c" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG16963 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - " pupal stage , pharate adult stage | stage P10-15 " " cone cell

, organism

, ocellus retinula cell

, primary pigment cell

, ocellus corneagenous cell

, ocellus

" " adult stage , pupal stage | mid-late " " cornea

, lens

, primary pigment cell

" viable FBgn0036994 CG5199 - http://flybase.org/reports/FBgn0036994 protein_coding_gene nuclear membrane proteasome anchor ; GO:1990919 | inferred from biological aspect of ancestor with PANTHER:PTN001997857 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process ; GO:0071630 | inferred from biological aspect of ancestor with PANTHER:PTN001997857 proteasome localization ; GO:0031144 | inferred from mutant phenotype proteasome localization to nuclear periphery ; GO:1990920 | inferred from biological aspect of ancestor with PANTHER:PTN001997857 nuclear membrane ; GO:0031965 | colocalizes_with inferred from direct assay "CG5199, CUT8" IPR013868:Tethering factor for nuclear proteasome Cut8/Sts1 CG5199 11-Aug-17 DroID_v2017_08 - Scer\STS1 - - - - viable FBgn0037875 ZnT86D Zinc transporter 86D http://flybase.org/reports/FBgn0037875 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016323 zinc ion transmembrane transporter activity ; GO:0005385 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 cation transport ; GO:0006812 | inferred from electronic annotation with InterPro:IPR002524 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002524 response to zinc ion ; GO:0010043 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype regulation of sequestering of zinc ion ; GO:0061088 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002524 Golgi apparatus ; GO:0005794 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "dZnT86D, dZnT7, CG6672, ZnT86D, cg6672, dZNT86D" IPR002524:Cation efflux protein CG6672 11-Aug-17 DroID_v2017_08 "Drer\slc30a1b, Drer\slc30a5, Drer\slc30a1a, Drer\slc30a6, Drer\slc30a7" "Scer\COT1, Scer\MSC2, Scer\ZRC1" "Cele\ttm-1, Cele\cdf-1, Cele\Y105E8A.3" "Xtro\slc30a5, Xtro\slc30a7, Xtro\slc30a6, Xtro\slc30a1" "Mmus\Slc30a1, Mmus\Slc30a5, Mmus\Slc30a7, Mmus\Slc30a10, Mmus\Slc30a6, Mmus\Slc30a8" "Hsap\SLC30A1, Hsap\SLC30A8, Hsap\SLC30A6, Hsap\SLC30A5, Hsap\SLC30A7, Hsap\SLC30A10" "viable,visible,developmental rate defective,lethal - all die before end of larval stage,body color defective,lethal - all die during larval stage" eye FBgn0044422 M82-19 M82-19 http://flybase.org/reports/FBgn0044422 gene molecular_function ; GO:0003674 | no biological data available eye photoreceptor cell differentiation ; GO:0001754 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available M82-19 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002006 l(2)36Ca lethal (2) 36Ca http://flybase.org/reports/FBgn0002006 - gene - - - "l(2)HT-1, l(2L)HT-1, l(2)36Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039325 CG10560 - http://flybase.org/reports/FBgn0039325 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10560 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG10560 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\C29F7.1, Cele\dhs-27, Cele\C29F7.2, Cele\F59B1.8, Cele\nhr-246, Cele\H06H21.8, Cele\F59B1.10" - - - "viable,fertile,lethal" FBgn0260014 nds indios http://flybase.org/reports/FBgn0260014 gene - - - nds - - 11-Aug-17 DroID_v2017_08 - - - - - - "chorion,dorsal appendage,chorion | germline clone" FBgn0022012 l(2)k09107 lethal (2) k09107 http://flybase.org/reports/FBgn0022012 - gene - - - l(2)k09107 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032069 LManVI Lysosomal alpha-mannosidase VI http://flybase.org/reports/FBgn0032069 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR015341 alpha-mannosidase activity ; GO:0004559 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 mannose metabolic process ; GO:0006013 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 protein deglycosylation ; GO:0006517 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 - "LManVI, CG9468" "IPR000602:Glycoside hydrolase family 38, N-terminal domain, IPR011013:Galactose mutarotase-like domain, IPR011682:Glycosyl hydrolase family 38, C-terminal, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR015341:Glycoside hydrolase family 38, central domain, IPR027291:Glycoside hydrolase 38/57, N-terminal domain, IPR028995:Glycoside hydrolase families 57/38, central domain" CG9468 11-Aug-17 DroID_v2017_08 "Drer\man2b1, Drer\man2a2, Drer\man2b2" - Cele\aman-1 "Xtro\man2a1, Xtro\man2b1, Xtro\man2b2, Xtro\man2a2" "Mmus\Man2b1, Mmus\Man2a1, Mmus\Man2b2" "Hsap\MAN2B1, Hsap\MAN2A1, Hsap\MAN2B2, Hsap\MAN2A2" viable DRSC03224 I 1.522227275 1.555148586 1.411921477 -0.442056916 -0.4299295 0.315761799 FBgn0035710 SP1173 SP1173 http://flybase.org/reports/FBgn0035710 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG10121, SP1173" "IPR020846:Major facilitator superfamily domain, IPR024989:Major facilitator superfamily associated domain" CG10121 11-Aug-17 DroID_v2017_08 "Drer\mfsd6a, Drer\mfsd6l, Drer\mfsd6b" - Cele\R13A5.9 "Xtro\mfsd6l, Xtro\mfsd6" "Mmus\Mfsd6l, Mmus\Mfsd6" "Hsap\MFSD6L, Hsap\MFSD6" "viable,fertile" FBgn0060458 l(3)S117902 lethal (3) S117902 http://flybase.org/reports/FBgn0060458 gene - - - "1179/02, l(3)S117902" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032818 CG10628 - http://flybase.org/reports/FBgn0032818 protein_coding_gene "molecular_function ; GO:0003674 | no biological data available GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006073, InterPro:IPR006169, InterPro:IPR014100, InterPro:IPR031167 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR014100 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR014100" biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10628 "IPR006073:GTP binding domain, IPR006169:GTP1/OBG domain, IPR014100:GTP-binding protein Obg/CgtA, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031167:OBG-type guanine nucleotide-binding (G) domain" CG10628 11-Aug-17 DroID_v2017_08 "Drer\mtg2, Drer\gtpbp10" "Scer\MTG2, Scer\MSS1" "Cele\C26E6.12, Cele\M01E5.2" "Xtro\gtpbp10, Xtro\mtg2" "Mmus\Mtg2, Mmus\Gtpbp10" "Hsap\GTPBP10, Hsap\MTG2" "viable,visible" trichogen cell DRSC02080 IE 2.75036691 -0.201003573 4.769571053 -0.300649533 0.770052649 -0.581744254 FBgn0023418 8H11 8H11 http://flybase.org/reports/FBgn0023418 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available 8H11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266199 CR44894 - http://flybase.org/reports/FBgn0266199 non_protein_coding_gene - - - CR44894 - CR44894 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028474 CG4119 - http://flybase.org/reports/FBgn0028474 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000428218 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" nucleus ; GO:0005634 | inferred by curator from GO:0000381 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "BcDNA:LD23634, cg4119, CG4119, BcDNA.LD23634" "IPR000504:RNA recognition motif domain, IPR002483:PWI domain, IPR034268:RBM25, RNA recognition motif" CG4119 11-Aug-17 DroID_v2017_08 Drer\rbm25b Scer\SNU71 Cele\W04D2.6 Xtro\rbm25 Mmus\Rbm25 Hsap\RBM25 viable FBgn0036187 RIOK1 RIO kinase 1 http://flybase.org/reports/FBgn0036187 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000687, InterPro:IPR018935 protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR000687, InterPro:IPR017407, InterPro:IPR018935 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with SGD:S000005645" cellular response to starvation ; GO:0009267 | inferred from expression pattern protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000005645 positive regulation of glial cell proliferation ; GO:0060252 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005645 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005645 "CG11660, RIOK1, dRIOK1, Rio1" "IPR000687:RIO kinase, IPR011009:Protein kinase-like domain, IPR018935:RIO kinase, conserved site, IPR017407:Serine/threonine-protein kinase Rio1" CG11660 11-Aug-17 DroID_v2017_08 "Drer\riok3, Drer\riok1" Scer\RIO1 "Cele\try-1, Cele\riok-3, Cele\riok-1" "Xtro\riok3, Xtro\riok1" "Mmus\Riok3, Mmus\Riok1" "Hsap\RIOK3, Hsap\RIOK1" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0001543 l(1)14Fa lethal (1) 14Fa http://flybase.org/reports/FBgn0001543 - gene - - - "l(1)16f, 16f, l(1)14Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002755 mit(1)5 mitotic 5 http://flybase.org/reports/FBgn0002755 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0261294 CheB74a Chemosensory protein B 74a http://flybase.org/reports/FBgn0261294 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model "CheB74a, CG33924" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG33924 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025130 su(RpII140[Z36])S17 su(RpII140[Z36])S17 http://flybase.org/reports/FBgn0025130 - gene - - - "Z36[S17], su(RpII140[Z36])S17" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024328 Methyl-transferase-like Methyl transferase like http://flybase.org/reports/FBgn0024328 - gene - - - Methyl-transferase-like - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005295 mei-2593 meiotic 2593 http://flybase.org/reports/FBgn0005295 - gene - - - "2593, mei-2593" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0020515 A3 A3 http://flybase.org/reports/FBgn0020515 - gene molecular_function ; GO:0003674 | no biological data available - - A3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020790 pyg pygoscelis http://flybase.org/reports/FBgn0020790 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "pomp, pen, pyg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone" FBgn0029804 CG3097 - http://flybase.org/reports/FBgn0029804 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG3097 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG3097 11-Aug-17 DroID_v2017_08 "Drer\cpb1, Drer\cpa4, Drer\cpa5, Drer\cpa2, Drer\cpa1, Drer\cpa6, Drer\cpb2, Drer\cpo" Scer\ECM14 "Cele\Y47G6A.19, Cele\Y59C2A.1, Cele\T06A4.1, Cele\F02D8.4, Cele\suro-1, Cele\T06A4.3, Cele\Y18H1A.9, Cele\ZC434.9, Cele\W01A8.6" "Xtro\cpa1, Xtro\cpb1, Xtro\cpa6, Xtro\cpo, Xtro\cpa3, Xtro\cpb2" "Mmus\Cpa3, Mmus\Cpa6, Mmus\Cpb1, Mmus\Cpa1, Mmus\Cpa4, Mmus\Cpb2, Mmus\Cpa5, Mmus\Cpa2" "Hsap\CPA1, Hsap\CPA6, Hsap\CPA5, Hsap\CPA3, Hsap\CPA4, Hsap\CPO, Hsap\CPB2, Hsap\CPB1, Hsap\CPA2" "viable,fertile" FBgn0285892 tea telomere ends associated http://flybase.org/reports/FBgn0285892 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "tea, III, l(2)46Cc, CG30007, Tea, CG12138, l(2)SH0071, l(2)SH2 0071" - CG30007 11-Aug-17 DroID_v2017_08 "Drer\elovl4b, Drer\elovl8a, Drer\elovl2, Drer\elovl4a, Drer\elovl7a, Drer\elovl5, Drer\elovl8b, Drer\elovl1a, Drer\elovl7b, Drer\elovl1b" "Scer\ELO3, Scer\ELO2" - "Xtro\elovl7, Xtro\elovl2, Xtro\elovl1, Xtro\elovl5" "Mmus\Elovl2, Mmus\Elovl5, Mmus\Elovl4, Mmus\Elovl7, Mmus\Elovl1" "Hsap\ELOVL4, Hsap\ELOVL7, Hsap\ELOVL2, Hsap\ELOVL1, Hsap\ELOVL5" "lethal,male sterile,lethal - all die before end of larval stage,some die during larval stage" FBgn0002302 l(3)84Bb lethal (3) 84Bb http://flybase.org/reports/FBgn0002302 - gene - - - "l(3)84Ba, l(3)84Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive,visible" FBgn0086672 snoRNA:Or-aca5 snoRNA:Or-aca5 http://flybase.org/reports/FBgn0086672 snoRNA_gene - - - "snoRNA:227, DmOr_aca5, Dm-227, snoR227, CR33637, DmOr_aca5(SnoR227), DmOr_aca5 snoRNA, snoRNA:Or-aca5, Or-aca5, chr2R:4607488..4607590" - CR33637 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020011 Fab-7 Fab-7 http://flybase.org/reports/FBgn0020011 - insulator - - - "Fab7, Fab-7 PRE, FAB-7, Fab7 PRE, Fab-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063423 l(2)45Ar lethal (2) 45Ar http://flybase.org/reports/FBgn0063423 gene - - - l(2)45Ar - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002904 mus307 mutagen-sensitive 307 http://flybase.org/reports/FBgn0002904 - gene - - - mus307 - - 11-Aug-17 DroID_v2017_08 - - - - - - "radiation sensitive,chemical sensitive,recessive" FBgn0025109 Bem46 Bem46 http://flybase.org/reports/FBgn0025109 FBgn0031486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "c1.6, CG18642, Bem46" "IPR029058:Alpha/Beta hydrolase fold, IPR005645:Serine hydrolase FSH, IPR022742:Serine aminopeptidase, S33" CG18642 11-Aug-17 DroID_v2017_08 "Drer\abhd17c, Drer\abhd13" Scer\YNL320W "Cele\aho-3, Cele\C50B6.9, Cele\F01D5.7" "Xtro\abhd13, Xtro\abhd17b, Xtro\abhd17c" "Mmus\Abhd13, Mmus\Abhd17b, Mmus\Abhd17c" "Hsap\ABHD17B, Hsap\ABHD13, Hsap\ABHD17C" viable FBgn0266032 CR44797 - http://flybase.org/reports/FBgn0266032 non_protein_coding_gene - - - CR44797 - CR44797 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021993 l(2)k09601 lethal (2) k09601 http://flybase.org/reports/FBgn0021993 - gene - - - l(2)k09601 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086665 snoRNA:Psi18S-1377a snoRNA:Psi18S-1377a http://flybase.org/reports/FBgn0086665 snoRNA_gene - - - "psi18S-1377a, snoRNA:328, Psi 18S-1377a(SnoR328), snoR328, Psi18S-1377a, snoRNA:Psi18S-1377a, Dm-328, CR33750, chr3R:26033540..26033785" - CR33750 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265302 CR44275 - http://flybase.org/reports/FBgn0265302 non_protein_coding_gene - - - CR44275 - CR44275 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035777 CG8563 - http://flybase.org/reports/FBgn0035777 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG8563 "IPR009020:Protease propeptides/proteinase inhibitor I9, IPR003146:Carboxypeptidase, activation peptide, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR000834:Peptidase M14, carboxypeptidase A" CG8563 11-Aug-17 DroID_v2017_08 "Drer\cpa4, Drer\cpo, Drer\cpa6, Drer\cpa2, Drer\cpa1, Drer\cpb1, Drer\cpa5, Drer\cpb2" Scer\ECM14 "Cele\T06A4.1, Cele\Y47G6A.19, Cele\W01A8.6, Cele\Y18H1A.9, Cele\ZC434.9, Cele\Y59C2A.1, Cele\F02D8.4, Cele\suro-1, Cele\T06A4.3" "Xtro\cpb2, Xtro\cpb1, Xtro\cpa3, Xtro\cpo, Xtro\cpa1" "Mmus\Cpa3, Mmus\Cpa6, Mmus\Cpa1, Mmus\Cpa5, Mmus\Cpb2, Mmus\Cpa4, Mmus\Cpa2, Mmus\Cpn1, Mmus\Cpb1" "Hsap\CPA3, Hsap\CPA5, Hsap\CPA4, Hsap\CPO, Hsap\CPNE1, Hsap\CPB1, Hsap\CPA6, Hsap\CPA1, Hsap\CPA2, Hsap\CPB2" "partially lethal - majority die,some die during pupal stage" FBgn0022094 l(2)k07237 lethal (2) k07237 http://flybase.org/reports/FBgn0022094 - gene - - - l(2)k07237 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" crystal cell FBgn0037384 dgrn degringolade http://flybase.org/reports/FBgn0037384 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 SUMO binding ; GO:0032183 | inferred from physical interaction with smt3 zinc ion binding ; GO:0008270 | inferred from sequence model RNA polymerase II repressing transcription factor binding ; GO:0001103 | inferred from physical interaction with h ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay "regulation of establishment of protein localization ; GO:0070201 | inferred from direct assay protein ubiquitination ; GO:0016567 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from genetic interaction with E(spl)m8-HLH inferred from genetic interaction with E(spl)m8-HLH inferred from genetic interaction with E(spl)m8-HLH sex determination ; GO:0007530 | inferred from mutant phenotype regulation of protein binding ; GO:0043393 | inferred from direct assay double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000548413" "nucleus ; GO:0005634 | inferred from direct assay SUMO-targeted ubiquitin ligase complex ; GO:0033768 | inferred by curator from GO:0032183,GO:0061630 nuclear periphery ; GO:0034399 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay" "dgrn, CG10981, STUbL, Dgrn" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10981 11-Aug-17 DroID_v2017_08 "Drer\trim35-28, Drer\trim35-7, Drer\trim35-24, Drer\LOC100536643, Drer\trim35-12, Drer\si:ch73-106l15.3, Drer\trim35-9, Drer\trim35-35, Drer\trim35-33, Drer\trim35-30, Drer\trim35-19, Drer\trim35-31, Drer\trim35-25, Drer\rnf20, Drer\trim35-3, Drer\trim35-13, Drer\si:ch211-12p12.2, Drer\trim35-20, Drer\pex10, Drer\si:ch211-247l8.8, Drer\si:ch73-106l15.2, Drer\trim35-23, Drer\si:ch211-175l6.2, Drer\trim35-34, Drer\si:ch73-166o21.1, Drer\rnf185, Drer\trim35-1, Drer\rnf4, Drer\trim35-10, Drer\si:ch1073-324l1.1, Drer\rnf220a, Drer\trim35-29, Drer\trim35-14, Drer\ftr70" "Scer\PEX10, Scer\SLX8, Scer\BRE1" "Cele\Y54E10BR.3, Cele\rnf-5, Cele\rfp-1, Cele\C28G1.6, Cele\T01G5.7, Cele\Y38C1AA.6, Cele\Y47G6A.31" "Xtro\trim69.2, Xtro\rnf220.1, Xtro\rnf5, Xtro\rnf4" "Mmus\Trim7, Mmus\Rnf40, Mmus\Rnf20, Mmus\Rnf5, Mmus\Trim26, Mmus\Trim39, Mmus\Rnf4, Mmus\Pex10, Mmus\Trim10, Mmus\Trim35, Mmus\Rnf185" "Hsap\TRIM35, Hsap\PEX10, Hsap\TRIM10, Hsap\RNF40, Hsap\RNF185, Hsap\RNF20, Hsap\TRIM26, Hsap\RNF4, Hsap\TRIM39, Hsap\TRIM7, Hsap\RNF5" "female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal,male,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" FBgn0031496 CG17258 - http://flybase.org/reports/FBgn0031496 protein_coding_gene - - - CG17258 IPR026174:Coiled-coil domain-containing protein 191 CG17258 11-Aug-17 DroID_v2017_08 Drer\ccdc191 - - - Mmus\Ccdc191 Hsap\CCDC191 "viable,visible" "chaeta,supernumerary" DRSC00495 E 0.346568903 1.389608345 2.617268929 1.009217771 0.240223121 -0.238024844 FBgn0069120 ms(3)Z2995 ms(3)Z2995 http://flybase.org/reports/FBgn0069120 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(3)Z2995 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile testis FBgn0038401 CG5916 - http://flybase.org/reports/FBgn0038401 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG5916 IPR000195:Rab-GTPase-TBC domain CG5916 11-Aug-17 DroID_v2017_08 "Drer\sgsm3, Drer\si:dkey-110k5.6, Drer\tbc1d10ab, Drer\grtp1a, Drer\tbc1d30, Drer\grtp1b, Drer\tbc1d2, Drer\tbc1d2b, Drer\tbc1d9" "Scer\MDR1, Scer\MSB4, Scer\MSB3, Scer\BUB2" "Cele\tbc-10, Cele\tbc-18, Cele\tbc-9, Cele\tbc-6, Cele\tbc-19, Cele\tbc-2" "Xtro\grtp1, Xtro\tbc1d2b, Xtro\tbc1d10a" "Mmus\Tbc1d9b, Mmus\Tbc1d2, Mmus\Tbc1d10a, Mmus\Tbc1d8, Mmus\Tbc1d2b, Mmus\Tbc1d30, Mmus\Grtp1, Mmus\Tbc1d8b, Mmus\Tbc1d9, Mmus\Tbc1d10b, Mmus\Sgsm3" "Hsap\TBC1D10A, Hsap\TBC1D7-LOC100130357, Hsap\TBC1D8, Hsap\TBC1D10B, Hsap\TBC1D9, Hsap\SGSM3, Hsap\TBC1D8B, Hsap\GRTP1, Hsap\TBC1D2, Hsap\TBC1D9B, Hsap\TBC1D30, Hsap\TBC1D2B" FBgn0001949 l(2)27Db lethal (2) 27Db http://flybase.org/reports/FBgn0001949 - gene - - - "E, l(2)27Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032773 fon fondue http://flybase.org/reports/FBgn0032773 protein_coding_gene - hemolymph coagulation ; GO:0042381 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype hemolymph coagulation ; GO:0042381 | inferred from direct assay inferred from mutant phenotype hemolymph coagulation ; GO:0042381 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG15825, fon, Fon, FON" - CG15825 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of pupal stage,recessive,some die during pupal stage,wound healing defective,immune response defective,partially lethal - majority die" "larva,pupa,pupal spiracle,hemolymph,pupal cuticle" FBgn0061097 l(3)S009826b lethal (3) S009826b http://flybase.org/reports/FBgn0061097 gene - - - "0098/26, l(3)S009826b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003979 Vm26Aa Vitelline membrane 26Aa http://flybase.org/reports/FBgn0003979 - protein_coding_gene - vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from expression pattern oogenesis ; GO:0048477 | inferred from mutant phenotype vitelline envelope ; GO:0060388 | inferred from direct assay "Vm26Aa, sV17, VM26A.1, Vm26A.1, Vm26A1, Vm26A, TU-2, CG9048, VM26Aa" IPR013135:Vitelline membrane cysteine-rich domain CG9048 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage | stage S8-10 , adult stage && oogenesis stage | stage S8-10 , oogenesis stage | stage S8-11 , adult stage && oogenesis stage " " oocyte

, follicle cell

" " oogenesis stage | stage S10-14 && adult stage | female , embryonic stage " " organism

, vitelline membrane

" viable FBgn0034307 CG10914 - http://flybase.org/reports/FBgn0034307 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006073 - - CG10914 "IPR006073:GTP binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10914 11-Aug-17 DroID_v2017_08 "Drer\noa1, Drer\LOC101883563, Drer\pigp" Scer\NUG1 Cele\Y48E1B.2 "Xtro\noa1, Xtro\pigp" "Mmus\Noa1, Mmus\Pigp" "Hsap\PIGP, Hsap\NOA1" "partially lethal - majority die,some die during pupal stage" FBgn0010143 l(2)Sp18 lethal (2) Sp18 http://flybase.org/reports/FBgn0010143 - gene - - - l(2)Sp18 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015612 Calpastatin Calpastatin http://flybase.org/reports/FBgn0015612 - gene cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from direct assay - - Calpastatin - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028329 l(1)G0299 lethal (1) G0299 http://flybase.org/reports/FBgn0028329 gene - - - l(1)G0299 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,male,female" FBgn0023142 WppA White prepupal locus A http://flybase.org/reports/FBgn0023142 - gene - - - "1, WppA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031992 CG8498 - http://flybase.org/reports/FBgn0031992 protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 - - CG8498 "IPR000582:Acyl-CoA-binding protein, ACBP, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR022408:Acyl-CoA-binding protein, ACBP, conserved site" CG8498 11-Aug-17 DroID_v2017_08 "Drer\LOC103909942, Drer\acbd5b, Drer\acbd4, Drer\zgc:92030, Drer\acbd6, Drer\acbd7, Drer\dbi, Drer\mettl23" Scer\ACB1 "Cele\maa-1, Cele\ech-4, Cele\acbp-6, Cele\acbp-1, Cele\acbp-5, Cele\acbp-4, Cele\acbp-3, Cele\acbp-7" "Xtro\mettl23, Xtro\acbd6, Xtro\eci2, Xtro\acbd5, Xtro\acbd7" "Mmus\Dbil5, Mmus\Acbd4, Mmus\Eci2, Mmus\Acbd7, Mmus\Dbi, Mmus\Acbd6, Mmus\Acbd5, Mmus\Mettl23" "Hsap\DBI, Hsap\ECI2, Hsap\METTL23, Hsap\ACBD4, Hsap\ACBD5, Hsap\ACBD7, Hsap\ACBD6" viable FBgn0037503 CG14598 - http://flybase.org/reports/FBgn0037503 protein_coding_gene - - - CG14598 - CG14598 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC12541 I 1.535334074 1.534834829 0.679083342 0.097024236 -0.17339263 1.122427761 FBgn0065179 l(3)SH004 lethal (3) SH004 http://flybase.org/reports/FBgn0065179 gene - - - "l(3)SH004, l(2)SH3 004" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028521 BG:DS03192.4 BG:DS03192.4 http://flybase.org/reports/FBgn0028521 gene - - - "DS03192.4, DS003192.4, BG:DS03192.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015536 ros rosario http://flybase.org/reports/FBgn0015536 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "fs(3)ros, ros" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259873 Su(Ste):CR42442 Su(Ste):CR42442 http://flybase.org/reports/FBgn0259873 non_protein_coding_gene - - - "Su(Ste):CR42442, RR41471, CR42442" - CR42442 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005616 msl-2 male-specific lethal 2 http://flybase.org/reports/FBgn0005616 "FBgn0001317, FBgn0002852" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 DNA binding ; GO:0003677 | inferred from direct assay chromatin binding ; GO:0003682 | contributes_to inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with msl-1 dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome ; GO:0016457 | traceable author statement dosage compensation by hyperactivation of X chromosome ; GO:0009047 | non-traceable author statement histone H4-K16 acetylation ; GO:0043984 | inferred from biological aspect of ancestor with PANTHER:PTN001042522 protein ubiquitination ; GO:0016567 | inferred from direct assay dosage compensation ; GO:0007549 | inferred from mutant phenotype protein autoubiquitination ; GO:0051865 | inferred from direct assay "X chromosome ; GO:0000805 | non-traceable author statement X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | non-traceable author statement X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | traceable author statement X chromosome ; GO:0000805 | inferred from direct assay MSL complex ; GO:0072487 | inferred from direct assay dosage compensation complex ; GO:0046536 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay" "MSL2, msl2, Msl2, MSL, msl, MSL-2, km(2)A, kmA, CG3241, msl-2, Msl 1-3, Msl-2" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR032049:E3 ubiquitin-protein ligase Msl2, CXC domain, IPR032043:E3 ubiquitin-protein ligase Msl2, zinc RING finger, IPR033467:Tesmin/TSO1-like CXC domain" CG3241 11-Aug-17 DroID_v2017_08 "Drer\msl2b, Drer\msl2a" - - Xtro\msl2 Mmus\Msl2 Hsap\MSL2 " larval stage | male , adult stage | female , adult stage | male , larval stage | female " " adult stage | male , larval stage | male " "lethal,male,female sterile,partially,developmental rate defective,female,viable,poor,heat sensitive,wild-type,visible,female limited,recessive,lethal - all die before end of larval stage,some die during larval stage" "eye,female" DRSC00829 I -0.194014437 1.848854694 -0.242461389 0.822805245 1.182746631 -0.325735184 FBgn0043594 E(ro[DOM])2051 E(ro[DOM])2051 http://flybase.org/reports/FBgn0043594 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available E(ro[DOM])2051 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065889 l(2)SH0222 lethal (2) SH0222 http://flybase.org/reports/FBgn0065889 gene - - - l(2)SH0222 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267034 CR45478 - http://flybase.org/reports/FBgn0267034 non_protein_coding_gene - - - CR45478 - CR45478 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035604 Ir64a Ionotropic receptor 64a http://flybase.org/reports/FBgn0035604 protein_coding_gene AMPA glutamate receptor activity ; GO:0004971 | inferred from biological aspect of ancestor with PANTHER:PTN000438080 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model olfactory receptor activity ; GO:0004984 | contributes_to inferred from direct assay extracellular ligand-gated ion channel activity ; GO:0005230 | contributes_to inferred from direct assay cellular response to acidic pH ; GO:0071468 | inferred from mutant phenotype cellular response to acetate ; GO:0071311 | inferred from direct assay olfactory behavior ; GO:0042048 | inferred from mutant phenotype response to chlorate ; GO:0010157 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern positive regulation of calcium-mediated signaling ; GO:0050850 | inferred from mutant phenotype response to acetate ; GO:0010034 | inferred from mutant phenotype AMPA glutamate receptor complex ; GO:0032281 | inferred from biological aspect of ancestor with PANTHER:PTN000438080 integral component of membrane ; GO:0016021 | inferred from sequence model sensory dendrite ; GO:0071683 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from direct assay "CT29782, Ir64a, IR64a, Ir64, CG10633, DmelIR64a, ir64a" IPR001320:Ionotropic glutamate receptor CG10633 11-Aug-17 DroID_v2017_08 "Drer\grid1b, Drer\grid1a, Drer\gria2a, Drer\gria3a, Drer\gria2b, Drer\gria4b, Drer\LOC100537813, Drer\gria4a, Drer\gria3b" - Cele\glr-8 - "Mmus\Gria3, Mmus\Gria2, Mmus\Grid1, Mmus\Grik4, Mmus\Gria4, Mmus\Gria1" "Hsap\GRIA3, Hsap\GRID1, Hsap\GRIA1, Hsap\GRIA2, Hsap\GRIA4" "viable,smell perception defective,neurophysiology defective,recessive,auditory perception defective" "adult lateral horn type II neuron,antennal lobe glomerulus DP1m" FBgn0028175 l(3)S026409a lethal (3) S026409a http://flybase.org/reports/FBgn0028175 gene - - - "0264/09, l(3)S026409, l(3)S026409a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0016059 Sema1b Semaphorin 1b http://flybase.org/reports/FBgn0016059 "FBgn0023424, FBgn0028501" protein_coding_gene - embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from expression pattern cytosol ; GO:0005829 | inferred from direct assay "CG6446, Sema1b, Sema 1b, Sema III, sema-III, D-semaIII, BcDNA:GH03186, sema1b, Sema-1b" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001627:Sema domain, IPR027231:Semaphorin" CG6446 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-168n16.1, Drer\sema6d, Drer\si:dkey-49n23.1, Drer\sema3h, Drer\sema3fa, Drer\sema3e, Drer\si:ch211-129c21.1, Drer\sema4e, Drer\sema3fb, Drer\sema7a, Drer\sema6e, Drer\LOC798168, Drer\sema3aa, Drer\sema5bb, Drer\sema3b, Drer\sema3gb, Drer\sema4c, Drer\sema3bl, Drer\sema6dl, Drer\si:ch211-113g11.6, Drer\sema6bb, Drer\sema3ab, Drer\sema6a, Drer\sema4ba, Drer\sema5ba, Drer\sema3ga, Drer\rttn, Drer\sema5a, Drer\sema4ga, Drer\sema3d, Drer\sema4gb, Drer\stap2a, Drer\sema3c, Drer\sema4d, Drer\sema4ab" - "Cele\mab-20, Cele\smp-1, Cele\F23H12.5, Cele\smp-2" "Xtro\sema6a, Xtro\sema3f, Xtro\sema3d, Xtro\sema5b, Xtro\sema4c, Xtro\sema4d, Xtro\sema3c, Xtro\sema3b, Xtro\sema3a, Xtro\sema4a, Xtro\sema6d, Xtro\sema4g, Xtro\sema4b, Xtro\sema6b" "Mmus\Sema5a, Mmus\Sema4f, Mmus\Sema4b, Mmus\Sema6a, Mmus\Sema4a, Mmus\Sema3f, Mmus\Sema3e, Mmus\Sema3c, Mmus\Sema3g, Mmus\Sema6b, Mmus\Sema7a, Mmus\Sema6c, Mmus\Sema3a, Mmus\Sema4g, Mmus\Sema3b, Mmus\Sema3d, Mmus\Sspo, Mmus\Sema6d, Mmus\Sema4d, Mmus\Sema5b" "Hsap\SEMA5B, Hsap\SEMA4G, Hsap\SEMA6D, Hsap\SEMA4D, Hsap\SEMA6B, Hsap\SEMA3G, Hsap\SEMA3F, Hsap\SEMA6A, Hsap\SEMA4A, Hsap\SEMA4F, Hsap\SEMA5A, Hsap\SEMA7A, Hsap\SEMA4B, Hsap\SEMA4C, Hsap\SEMA3E, Hsap\SEMA3A, Hsap\SEMA3D, Hsap\SEMA3C, Hsap\SEMA6C" " embryonic stage | stage 5-10 , embryonic stage && pupal stage , adult stage && oogenesis stage | stage S10 , embryonic stage | stage 2 , embryonic stage | stage 12-15 , adult stage && oogenesis stage | stage S2-8 " " mesectoderm

, nurse cell

,

ubiquitous , ectoderm

, ovariole

" neuroanatomy defective "filamentous actin,intersegmental nerve" FBgn0040514 CG17169 - http://flybase.org/reports/FBgn0040514 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17169 - CG17169 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000533 ea easter http://flybase.org/reports/FBgn0000533 - protein_coding_gene serine-type peptidase activity ; GO:0008236 | non-traceable author statement peptidase activity ; GO:0008233 | traceable author statement serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from direct assay "proteolysis ; GO:0006508 | traceable author statement Toll signaling pathway ; GO:0008063 | non-traceable author statement zymogen activation ; GO:0031638 | inferred from direct assay proteolysis ; GO:0006508 | inferred from sequence model Toll signaling pathway ; GO:0008063 | traceable author statement maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | traceable author statement dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | traceable author statement" extracellular region ; GO:0005576 | inferred from direct assay "ea, SP24, c-SP24, CG4920, EA" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG4920 11-Aug-17 DroID_v2017_08 "Drer\st14b, Drer\masp2, Drer\si:dkey-78l4.10" - Cele\try-1 - "Mmus\Klk1b5, Mmus\Klk1b1" Hsap\KLK1 " oogenesis stage && adult stage | female , embryonic stage | early " ovary

"female fertile,wild-type,female sterile,dominant,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,viable,germline clone,non-rescuable maternal effect,heat sensitive" "embryonic/first instar larval cuticle,maternal effect,embryo,ventral,embryonic epidermis,head,extended germ band embryo,dorsal closure embryo,ventral furrow,denticle belt,cephalic furrow,dorsal fold,filzkorper,dorsal hair,embryonic head,heat sensitive,cephalopharyngeal skeleton" FBgn0283741 prage prage http://flybase.org/reports/FBgn0283741 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 molecular_function ; GO:0003674 | no biological data available egg activation ; GO:0007343 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "prg, CG42666, prage, CG14801, CG14799, CG14800, CG17968, EG:137E7.1, EG:131F2.2" "IPR012337:Ribonuclease H-like domain, IPR013520:Exonuclease, RNase T/DNA polymerase III" CG42666 11-Aug-17 DroID_v2017_08 "Drer\rexo1, Drer\zgc:152968" "Scer\RNH70, Scer\REX3" "Cele\C05C8.5, Cele\Y56A3A.33, Cele\pqe-1" "Xtro\rexo1, Xtro\LOC100036702, Xtro\LOC100158551" "Mmus\2610020H08Rik, Mmus\Rexo1" "Hsap\LOC101929627, Hsap\REXO1, Hsap\LOC81691, Hsap\LOC100288562" FBgn0038525 CG14329 - http://flybase.org/reports/FBgn0038525 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14329 - CG14329 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC14808 I 0.098117955 1.8109032 -0.422408207 -1.219247385 -0.485741985 0.713217373 FBgn0261699 CR42735 - http://flybase.org/reports/FBgn0261699 non_protein_coding_gene - - - "CG42735, HDC01070, CR42735" - CR42735 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040649 CG15461 - http://flybase.org/reports/FBgn0040649 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15461 - CG15461 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069141 mcl(3)Z5468 mcl(3)Z5468 http://flybase.org/reports/FBgn0069141 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z5468 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0002796 ms(1)4 male sterile (1) 4 http://flybase.org/reports/FBgn0002796 - gene - - - ms(1)4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile,viable" "major mitochondrial derivative,spermatozoon" FBgn0041110 medo medo http://flybase.org/reports/FBgn0041110 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available medo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027140 l(3)77Ea lethal (3) 77Ea http://flybase.org/reports/FBgn0027140 - gene - - - l(3)77Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267631 CR45969 - http://flybase.org/reports/FBgn0267631 non_protein_coding_gene - - - CR45969 - CR45969 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259231 CCKLR-17D1 Cholecystokinin-like receptor at 17D1 http://flybase.org/reports/FBgn0259231 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity gastrin receptor activity ; GO:0015054 | NOT inferred from direct assay neuropeptide receptor activity ; GO:0008188 | inferred from physical interaction with Dsk neuropeptide receptor activity ; GO:0008188 | inferred from sequence model cholecystokinin receptor activity ; GO:0004951 | NOT inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype positive regulation of cytosolic calcium ion concentration ; GO:0007204 | inferred from direct assay neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay multicellular organismal response to stress ; GO:0033555 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity terminal bouton ; GO:0043195 | colocalizes_with inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "CG42301, Dm CG6857, CG6857, anon-WO0170980.62, anon-WO0170980.61, CCKLR-17D1, CCKLR, DSK-R2, CCKLR-D1, DskR-2, SK-R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR009126:Cholecystokinin receptor, IPR017452:GPCR, rhodopsin-like, 7TM, IPR000314:Gastrin receptor" CG42301 11-Aug-17 DroID_v2017_08 "Drer\LOC100331465, Drer\si:dkey-1h24.2, Drer\cckar" - "Cele\ckr-2, Cele\R13H4.7, Cele\ckr-1, Cele\C34B4.3" Xtro\cckar "Mmus\Cckar, Mmus\Cckbr, Mmus\Gpr146" "Hsap\CCKBR, Hsap\GPR146, Hsap\CCKAR" "neuroanatomy defective,viable,lethal" "embryonic/larval neuromuscular junction,NMJ bouton,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage" FBgn0036014 CG3222 - http://flybase.org/reports/FBgn0036014 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs17c12.y1, NEST:bs17c12, CG3222" IPR003409:MORN motif CG3222 11-Aug-17 DroID_v2017_08 "Drer\als2a, Drer\jph3, Drer\jph1a, Drer\jph2, Drer\morn5, Drer\rsph10b, Drer\morn4, Drer\als2b, Drer\rsph1, Drer\jph1b, Drer\si:ch211-146m13.3" - - "Xtro\morn5, Xtro\rsph1, Xtro\als2, Xtro\jph1, Xtro\als2cl, Xtro\jph2, Xtro\rsph10b" "Mmus\Jph3, Mmus\Jph2, Mmus\Morn1, Mmus\Jph1, Mmus\Als2cl, Mmus\Als2, Mmus\Morn4, Mmus\Jph4, Mmus\Morn3, Mmus\Morn5, Mmus\Rsph1" "Hsap\ALS2CL, Hsap\ALS2, Hsap\MORN3, Hsap\JPH3, Hsap\JPH1, Hsap\RSPH10B2, Hsap\MORN4, Hsap\RSPH1, Hsap\JPH4, Hsap\MORN5, Hsap\RSPH10B, Hsap\JPH2, Hsap\MORN1" viable FBgn0046637 anon-38D.8 anon-38D.8 http://flybase.org/reports/FBgn0046637 gene - - - "38D.8, anon-38D.8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260265 GSd440 - http://flybase.org/reports/FBgn0260265 gene - - - GSd440 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0084001 CG41434 - http://flybase.org/reports/FBgn0084001 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG41434, lincRNA.226" - CG41434 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005732 l(1)TK214 lethal (1) TK214 http://flybase.org/reports/FBgn0005732 - gene - - - "l214, l(1)TK214" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0267444 Su(Ste):CR45794 Supressor of Stellate:CR45794 http://flybase.org/reports/FBgn0267444 non_protein_coding_gene - - - "Su(Ste):CR45794, CR45794" - CR45794 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065768 l(2)SH0470 lethal (2) SH0470 http://flybase.org/reports/FBgn0065768 gene - - - "l(2)SH0470, l(2)SH2 0470" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031957 TwdlE TweedleE http://flybase.org/reports/FBgn0031957 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlF chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlF proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlF "TwdlE, CG14534" IPR004145:Domain of unknown function DUF243 CG14534 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die" pupa FBgn0265907 CR44696 - http://flybase.org/reports/FBgn0265907 non_protein_coding_gene - - - CR44696 - CR44696 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259450 EP-572 - http://flybase.org/reports/FBgn0259450 gene - - - EP-572 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0000484 double double http://flybase.org/reports/FBgn0000484 - gene - - - double - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced" "postvertical bristle,wing" FBgn0002564 Lsp1gamma Larval serum protein 1 gamma http://flybase.org/reports/FBgn0002564 - protein_coding_gene - - larval serum protein complex ; GO:0005616 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Lsp1gamma, Lsp1, CG6821, Lsp-1gamma, DmeLSP1g, LSP-1gamma, Lsp1-gamma, LSP 1, LSP-1 gamma, LSP1, Lsp1gama, Lsp1[gamma]" "IPR000896:Hemocyanin/hexamerin middle domain, IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR008922:Uncharacterised domain, di-copper centre, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set" CG6821 11-Aug-17 DroID_v2017_08 - - "Cele\C49A9.3, Cele\F58F9.4, Cele\C49A9.2" - - - " larval stage | second instar -- larval stage | third instar , larval stage | third instar " embryonic/larval fat body

larval stage | second instar -- larval stage | third instar embryonic/larval fat body

"viable,fertile" egg FBgn0001279 Jag Jagged http://flybase.org/reports/FBgn0001279 - gene - - - Jag - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,recessive" "wing,eye" FBgn0264345 CR43801 - http://flybase.org/reports/FBgn0264345 non_protein_coding_gene - - - "CR43801, lincRNA.56" - CR43801 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259561 B2014 - http://flybase.org/reports/FBgn0259561 gene - - - B2014 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,tarsal segment" FBgn0034629 Acox57D-d acyl-Coenzyme A oxidase at 57D distal http://flybase.org/reports/FBgn0034629 protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012258, InterPro:IPR013786 acyl-CoA oxidase activity ; GO:0003997 | inferred from sequence or structural similarity with HGNC:119" fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:119 "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:119,HGNC:120 inferred from sequence model" "acox, D-acox, CG9709, Acox57Dd, Acox57D-d" "IPR002655:Acyl-CoA oxidase, C-terminal, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR012258:Acyl-CoA oxidase, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR029320:Acyl-coenzyme A oxidase, N-terminal" CG9709 11-Aug-17 DroID_v2017_08 "Drer\acox3, Drer\acox1" Scer\POX1 "Cele\F59F4.1, Cele\acdh-13, Cele\acox-3, Cele\acox-2, Cele\acox-1, Cele\acox-5, Cele\acox-4" "Xtro\acox1, Xtro\acox2" "Mmus\Acox2, Mmus\Acox3, Mmus\Acox1" "Hsap\ACOX1, Hsap\ACOX2, Hsap\ACOX3" viable FBgn0000813 fs(1)K163 female sterile (1) K163 http://flybase.org/reports/FBgn0000813 - gene - - - fs(1)K163 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority live,female sterile,recessive,lethal,rescuable maternal effect" egg FBgn0069308 X-40-2 X-40-2 http://flybase.org/reports/FBgn0069308 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-40-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,cephalopharyngeal skeleton" FBgn0039973 CG12563 - http://flybase.org/reports/FBgn0039973 protein_coding_gene - - - CG12563 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262656 Myc Myc http://flybase.org/reports/FBgn0262656 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with gro protein binding ; GO:0005515 | inferred from physical interaction with lid protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V3K3 inferred from physical interaction with UniProtKB:Q9VH07 DNA binding ; GO:0003677 | inferred from direct assay" "embryo development ending in birth or egg hatching ; GO:0009792 | inferred from expression pattern regulation of autophagy ; GO:0010506 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from expression pattern positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | traceable author statement negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with N cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype regulation of cell growth ; GO:0001558 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from genetic interaction with Egfr regulation of transcription from RNA polymerase III promoter ; GO:0006359 | inferred from direct assay inferred from physical interaction with Brf DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype positive regulation of growth ; GO:0045927 | inferred from mutant phenotype transcription from RNA polymerase I promoter ; GO:0006360 | inferred from direct assay positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | traceable author statement regulation of organ growth ; GO:0046620 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype positive regulation of neurogenesis ; GO:0050769 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | traceable author statement positive regulation of growth ; GO:0045927 | traceable author statement positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement positive regulation of developmental growth ; GO:0048639 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement regulation of trehalose metabolic process ; GO:0090062 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from genetic interaction with Egfr regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay" protein complex ; GO:0043234 | inferred from physical interaction with gro histone locus body ; GO:0035363 | colocalizes_with inferred from direct assay "dMyc, Myc, dmyc, d-myc, dm, myc, c-Myc, c-MYC, dMYC, CG10798, D-Myc, Dmyc, DMYc, dmyc1, dMyc1, l(1)G0139, anon-WO03040301.171, EG:BACN5I9.1, dm/dMyc, c-myc, bHLHe57, Dm, MYC, dm/myc, l(1)G0354, l(1)G0359, DM, da" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG10798 11-Aug-17 DroID_v2017_08 "Drer\mych, Drer\myclb, Drer\mycb, Drer\mycn, Drer\myca, Drer\mycla" - - "Xtro\mycn, Xtro\myc, Xtro\mycl" "Mmus\Mycs, Mmus\Bmyc, Mmus\Mycl, Mmus\Mycn, Mmus\Myc" "Hsap\MYC, Hsap\MYCL, Hsap\MYCN" " oogenesis stage , embryonic stage | early , embryonic stage | extended germ band , embryonic stage -- adult stage , embryonic stage | stage >8 " " organism | anterior & posterior

, anterior midgut proper primordium

, posterior midgut proper primordium

, mesoderm | presumptive

" FBgn0014017 Re Rough eye http://flybase.org/reports/FBgn0014017 - gene - - - Re - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" eye FBgn0266584 Gli::spi - http://flybase.org/reports/FBgn0266584 engineered_fusion_gene - - - Gli::spi - - 11-Aug-17 DroID_v2017_08 - - - - - - "photoreceptor,ectopic,somatic clone,eye disc,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7" FBgn0065330 l(2)SH1889 lethal (2) SH1889 http://flybase.org/reports/FBgn0065330 gene - - - "l(2)SH1889, l(2)SH2 1889" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022205 l(2)k04308 lethal (2) k04308 http://flybase.org/reports/FBgn0022205 - gene - - - l(2)k04308 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" crystal cell FBgn0051282 tRNA:Thr-AGT-1-4 transfer RNA:Threonine-AGT 1-4 http://flybase.org/reports/FBgn0051282 tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "AE002708.trna8-ThrAGT, tRNA:T:AGT:AE002708-a, CR31282, tRNA[[Thr]], chr3R.trna14-ThrAGT, tRNA-Thr-AGT-1-4, tRNA:Thr-AGT-1-4, tRNA:CR31282, ACU" - CR31282 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024943 PIP82 PIP82 http://flybase.org/reports/FBgn0024943 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available cellular response to light stimulus ; GO:0071482 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "CG11219, PIP82" - CG11219 11-Aug-17 DroID_v2017_08 - - Cele\dpy-22 - - - photoreceptor cell

viable FBgn0045961 Stalker\ORF2 Stalker element ORF2 http://flybase.org/reports/FBgn0045961 transposable_element_gene - - - Stalker\ORF2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060922 l(3)S042239 lethal (3) S042239 http://flybase.org/reports/FBgn0060922 gene - - - "0422/39, l(3)S042239" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031571 bark bark beetle http://flybase.org/reports/FBgn0031571 protein_coding_gene scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001190 carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 "liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype tricellular tight junction assembly ; GO:1904274 | inferred from mutant phenotype cell-cell junction maintenance ; GO:0045217 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype establishment of endothelial intestinal barrier ; GO:0090557 | inferred from mutant phenotype" "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001190, InterPro:IPR017448 septate junction ; GO:0005918 | inferred from direct assay tricellular tight junction ; GO:0061689 | inferred from direct assay septate junction ; GO:0005918 | inferred from mutant phenotype adherens junction ; GO:0005912 | inferred from direct assay" "bark, CG3921, aka" "IPR001190:SRCR domain, IPR000859:CUB domain, IPR006626:Parallel beta-helix repeat, IPR011050:Pectin lyase fold/virulence factor, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold, IPR017448:SRCR-like domain, IPR012334:Pectin lyase fold, IPR012332:P22 tailspike C-terminal domain-like" CG3921 11-Aug-17 DroID_v2017_08 "Drer\loxl3a, Drer\si:dkey-21h14.3, Drer\loxl2b, Drer\loxl3b, Drer\si:dkey-14d8.20, Drer\LOC101885539" - Cele\C06B8.7 Xtro\loxl2 "Mmus\Cd5, Mmus\Gm21451, Mmus\Loxl3, Mmus\Cd163l1, Mmus\Dmbt1, Mmus\5830411N06Rik, Mmus\5430419D17Rik" "Hsap\CD5, Hsap\LOXL3, Hsap\LOXL2, Hsap\DMBT1, Hsap\CD163L1" "lethal,recessive" FBgn0267366 mil milkah http://flybase.org/reports/FBgn0267366 protein_coding_gene histone binding ; GO:0042393 | inferred from direct assay memory ; GO:0007613 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype nucleosome assembly ; GO:0006334 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR002164 cytosol ; GO:0005829 | inferred from direct assay Nebenkern ; GO:0016006 | inferred from direct assay "CG5017, milkah, mil, hanabi, tNAP" IPR002164:Nucleosome assembly protein (NAP) CG5017 11-Aug-17 DroID_v2017_08 "Drer\nap1l1, Drer\nap1l4b, Drer\nap1l4a" "Scer\NAP1, Scer\VPS75" Cele\nap-1 "Xtro\nap1l4, Xtro\nap1l1" "Mmus\Nap1l2, Mmus\Nap1l1, Mmus\Nap1l3, Mmus\Nap1l4, Mmus\Nap1l5" "Hsap\NAP1L4, Hsap\NAP1L3, Hsap\NAP1L1, Hsap\NAP1L5, Hsap\NAP1L2" FBgn0029799 CG15772 - http://flybase.org/reports/FBgn0029799 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR001337 - viral capsid ; GO:0019028 | inferred from electronic annotation with InterPro:IPR001337 CG15772 "IPR001337:Tobacco mosaic virus-like, coat protein" CG15772 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0000037 mAChR-A "muscarinic Acetylcholine Receptor, A-type" http://flybase.org/reports/FBgn0000037 - protein_coding_gene G-protein coupled acetylcholine receptor activity ; GO:0016907 | inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity G-protein coupled acetylcholine receptor activity ; GO:0016907 | inferred from sequence or structural similarity "phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway ; GO:0007207 | inferred from biological aspect of ancestor with PANTHER:PTN001207082 phospholipase C-activating G-protein coupled receptor signaling pathway ; GO:0007200 | inferred from direct assay G-protein coupled acetylcholine receptor signaling pathway ; GO:0007213 | inferred from sequence or structural similarity adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway ; GO:0007197 | inferred from biological aspect of ancestor with PANTHER:PTN001207082 synaptic transmission, cholinergic ; GO:0007271 | inferred from biological aspect of ancestor with PANTHER:PTN001207082 G-protein coupled acetylcholine receptor signaling pathway ; GO:0007213 | inferred from direct assay" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN001207082 integral component of plasma membrane ; GO:0005887 | inferred from direct assay "DM1, mAChR, Dm1, Acr60C, mAChR-1, CG4356, AcrC, mAcR60C, mAcR-60C, mAChR-A, mAChR A, Dm-mAChR-A, mAcR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000995:Muscarinic acetylcholine receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG4356 11-Aug-17 DroID_v2017_08 "Drer\chrm2b, Drer\chrm4a, Drer\chrm2a, Drer\chrm5b, Drer\hrh1, Drer\chrm1a, Drer\si:ch73-151m17.5, Drer\chrm1b, Drer\chrm3a, Drer\chrm5a, Drer\fmn2a, Drer\chrm3b" - Cele\gar-3 "Xtro\chrm3, Xtro\chrm2, Xtro\chrm1, Xtro\chrm5, Xtro\hrh1" "Mmus\Hrh1, Mmus\Chrm2, Mmus\Chrm3, Mmus\Chrm4, Mmus\Chrm1, Mmus\Chrm5" "Hsap\CHRM4, Hsap\CHRM1, Hsap\CHRM2, Hsap\CHRM5, Hsap\HRH1, Hsap\CHRM3" "viable,visible" mesothoracic tergum DRSC04702 IEK -1.892221833 -3.827775328 -3.300800693 -1.655518805 1.501080088 0.579795602 FBgn0005225 l(3)PL lethal Payne Left http://flybase.org/reports/FBgn0005225 - gene - - - l(3)PL - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060378 l(3)S135305 lethal (3) S135305 http://flybase.org/reports/FBgn0060378 gene - - - "1353/05, l(3)S135305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0039149 CG18428 - http://flybase.org/reports/FBgn0039149 protein_coding_gene - - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001414168 CG18428 "IPR019532:Nuclear RNA-splicing-associated protein, SR-25" CG18428 11-Aug-17 DroID_v2017_08 Drer\arl6ip4 - - Xtro\arl6ip4 Mmus\Arl6ip4 Hsap\ARL6IP4 viable FBgn0011588 eightless eightless http://flybase.org/reports/FBgn0011588 - gene - - - eightless - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039188 Golgin84 Golgin-84 http://flybase.org/reports/FBgn0039188 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from sequence or structural similarity with HGNC:4428 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with UniProtKB:Q8TBA6 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with HGNC:4428 "Golgi vesicle transport ; GO:0048193 | inferred from sequence or structural similarity with HGNC:4428 Golgi organization ; GO:0007030 | inferred from sequence or structural similarity with HGNC:4428 Golgi organization ; GO:0007030 | inferred from sequence or structural similarity with UniProtKB:Q8TBA6 Golgi vesicle transport ; GO:0048193 | inferred from sequence or structural similarity with UniProtKB:Q8TBA6 retrograde transport, vesicle recycling within Golgi ; GO:0000301 | inferred from biological aspect of ancestor with PANTHER:PTN000352326 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000352326" Golgi cisterna ; GO:0031985 | inferred from biological aspect of ancestor with PANTHER:PTN000352326 Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000352326 Golgi cisterna ; GO:0031985 | inferred from sequence or structural similarity with HGNC:4428 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with UniProtKB:Q8TBA6 "CG17785, Golgin84" IPR019177:Golgin subfamily A member 5 CG17785 11-Aug-17 DroID_v2017_08 "Drer\golga5, Drer\vipas39" - Cele\T24B1.1 "Xtro\golga5, Xtro\vipas39" "Mmus\Vipas39, Mmus\Golga5" "Hsap\VIPAS39, Hsap\GOLGA5" viable FBgn0266070 CR44823 - http://flybase.org/reports/FBgn0266070 non_protein_coding_gene - - - CR44823 - CR44823 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001324 kto kohtalo http://flybase.org/reports/FBgn0001324 FBgn0036912 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from direct assay RNA polymerase II transcription coactivator activity ; GO:0001105 | inferred from biological aspect of ancestor with PANTHER:PTN001795839 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KTX8 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P25008 inferred from physical interaction with UniProtKB:Q9VT57 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype sex comb development ; GO:0045498 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype "mediator complex ; GO:0016592 | inferred from physical interaction with CycC, Cdk8 mediator complex ; GO:0016592 | inferred from sequence or structural similarity polytene chromosome ; GO:0005700 | inferred from direct assay mediator complex ; GO:0016592 | inferred from direct assay core mediator complex ; GO:0070847 | inferred from physical interaction with MED17 mediator complex ; GO:0016592 | inferred from physical interaction with skd" "med12, psg14, MED12, Med12, Kto, CG8491, Srb8/KTO/TRAP230, Trap230, dTRAP230, SRB8, Kto/Med12, kto, siren1, dTrap230, med12/kto, l(3)76BDc, Brm @ Kto" "IPR019035:Mediator complex, subunit Med12, IPR011989:Armadillo-like helical, IPR021990:Mediator complex, subunit Med12, LCEWAV-domain" CG8491 11-Aug-17 DroID_v2017_08 Drer\med12 "Scer\SRB8, Scer\SNT1" "Cele\dpy-22, Cele\gei-8" - "Mmus\Med12l, Mmus\Med12" "Hsap\MED12L, Hsap\MED12" larval stage organism | ubiquitous

"lethal,recessive,visible,partially,somatic clone,partially lethal - majority die,some die during pupal stage" "embryonic/larval salivary gland,leg,eye disc,photoreceptor cell,antennal disc,heart primordium,wing disc,somatic clone,somatic clone - Minute background,sex comb tooth,prothoracic tarsal segment,eye,mesothoracic bristle,wing margin,wing,trichogen cell,mesothoracic tergum" DRSC10983 IEK 0.766543982 1.513557464 0.593589389 1.933794038 1.632139166 1.232516512 FBgn0029920 CR4575 - http://flybase.org/reports/FBgn0029920 pseudogene_attribute - - - "CR4575, CG4575, DM21" - CR4575 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262569 CG43109 - http://flybase.org/reports/FBgn0262569 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43109 - CG43109 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053238 Ste:CG33238 Ste:CG33238 http://flybase.org/reports/FBgn0053238 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG32605, CG33238, Ste:CG33238" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33238 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0261057 Sfp36F Seminal fluid protein 36F http://flybase.org/reports/FBgn0261057 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp36F, CG42605" - CG42605 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003569 supact suppressor activated http://flybase.org/reports/FBgn0003569 - gene - - - supact - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,female,macrochaeta" FBgn0000217 bre bright eye http://flybase.org/reports/FBgn0000217 - gene - - - bre - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,male fertile,fertile,female,poor,eye color defective,female fertile,reduced" "wing,abdomen,pigment cell,adult abdomen" FBgn0083025 snoRNA:Psi18S-640b snoRNA:Psi18S-640b http://flybase.org/reports/FBgn0083025 snoRNA_gene - - - "snoRNA:Psi18S-640b, psi18s-640b, CR34574" - CR34574 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065882 l(2)SH0232 lethal (2) SH0232 http://flybase.org/reports/FBgn0065882 gene - - - "l(2)SH0232, l(2)SH2 0232" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264880 CR44071 - http://flybase.org/reports/FBgn0264880 non_protein_coding_gene - - - CR44071 - CR44071 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067665 p70 p70 http://flybase.org/reports/FBgn0067665 gene - - - p70 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051614 His-Psi:CR31614 His-Psi:CR31614 http://flybase.org/reports/FBgn0051614 pseudogene_attribute - - - "CR31614, His-Psi:CR31614" - CR31614 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065138 l(3)SH114 lethal (3) SH114 http://flybase.org/reports/FBgn0065138 gene - - - "l(3)SH114, l(2)SH3 114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052764 CR32764 - http://flybase.org/reports/FBgn0052764 non_protein_coding_gene - - - CR32764 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011281 Obp83a Odorant-binding protein 83a http://flybase.org/reports/FBgn0011281 FBgn0010404 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 pheromone binding ; GO:0005550 | inferred from sequence or structural similarity odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "OS-F, DmelObp83a, Obp83a, PBPRP-3, 83a, PBPRP3, OS-F/PBP3, pbprp3(OS-F), PB-PRP3, Os-F, pbprp-3, PBP-H2, CG11421, obp83a, Pbprp3, Obp33a, pbprp3" IPR006170:Pheromone/general odorant binding protein CG11421 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " antennal segment 3

, sensillum trichodeum of antennal segment 3

, antennal segment 3 | anterior

" viable FBgn0030016 Or7a Odorant receptor 7a http://flybase.org/reports/FBgn0030016 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "7a, DOR30, 7D.1, CG10759, Or7a, DmOR7a, Or7A" "IPR004117:Olfactory receptor, insect" CG10759 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0032294 Vha16-5 Vacuolar H[+] ATPase 16kD subunit 5 http://flybase.org/reports/FBgn0032294 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from sequence model proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000813763" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR002379, InterPro:IPR011555 lysosomal lumen acidification ; GO:0007042 | inferred from biological aspect of ancestor with PANTHER:PTN000813819 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model" "vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model" "Vha16-5, vha16-5, CG6737" "IPR000245:V-ATPase proteolipid subunit, IPR002379:V-ATPase proteolipid subunit C-like domain, IPR011555:V-ATPase proteolipid subunit C, eukaryotic" CG6737 11-Aug-17 DroID_v2017_08 "Drer\atp6v0cb, Drer\atp6v0ca" "Scer\VMA3, Scer\VMA11" "Cele\vha-3, Cele\vha-1, Cele\vha-2" Xtro\atp6v0c Mmus\Atp6v0c Hsap\ATP6V0C "viable,body color defective" mesothoracic tergum DRSC02986 E 0.074986612 0.70753882 1.839979567 -0.014668084 -0.143423252 -0.02190931 FBgn0259374 EP-644 - http://flybase.org/reports/FBgn0259374 gene - - - EP-644 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0020775 vd vena decussata http://flybase.org/reports/FBgn0020775 - gene - - - vd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044328 CG32052 - http://flybase.org/reports/FBgn0044328 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843 - - "Smase, aSMase, BEST:HL01355, CG8163, CG32052" "IPR029052:Metallo-dependent phosphatase-like, IPR004843:Calcineurin-like phosphoesterase domain, ApaH type" CG32052 11-Aug-17 DroID_v2017_08 "Drer\smpdl3b, Drer\smpd1, Drer\smpdl3a" Scer\PPN1 "Cele\asm-1, Cele\asm-3, Cele\asm-2, Cele\ZK856.5" "Xtro\smpdl3b, Xtro\smpdl3a" "Mmus\Smpdl3a, Mmus\Smpdl3b, Mmus\Smpd1" "Hsap\SMPD1, Hsap\SMPDL3A, Hsap\SMPDL3B" viable FBgn0000668 fliB flightless B http://flybase.org/reports/FBgn0000668 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fliB - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,heat sensitive,jumping defective,flight defective" FBgn0024867 l(3)01619 lethal (3) 01619 http://flybase.org/reports/FBgn0024867 - gene - - - "1619, l(3)01619" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040000 CG15215 - http://flybase.org/reports/FBgn0040000 protein_coding_gene - - - CG15215 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266174 pre-mod(mdg4)-L - http://flybase.org/reports/FBgn0266174 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-L, CG44880" - CG44880 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261726 EC497 - http://flybase.org/reports/FBgn0261726 gene - - - EC497 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of first instar larval stage,some die during first instar larval stage" FBgn0011142 l(1)Q218 lethal (1) Q218 http://flybase.org/reports/FBgn0011142 FBgn0010210 gene - - - l(1)Q218 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259758 ms(3)Z1190 - http://flybase.org/reports/FBgn0259758 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "150-016, ms(3)Z1190, ms(3)150-16" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable" Y chromosome loop FBgn0025771 l(3)89Ad lethal (3) 89Ad http://flybase.org/reports/FBgn0025771 - gene - - - l(3)89Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005322 nmd no mitochondrial derivative http://flybase.org/reports/FBgn0005322 "FBgn0010653, FBgn0013648, FBgn0025974, FBgn0032212" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | inferred from sequence or structural similarity" "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap spermatid development ; GO:0007286 | traceable author statement" mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 "nmd, CG5395, DmCG5395, Msp1, l(2)08774, clone 1.79, anon-EST:Liang-1.79, ms(2)ry4, ms(2)4, Msp, Nmd" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5395 11-Aug-17 DroID_v2017_08 "Drer\atad1b, Drer\atad1a" Scer\MSP1 Cele\mspn-1 Xtro\atad1 Mmus\Atad1 Hsap\ATAD1 "male sterile,recessive,female fertile,lethal,visible,partially lethal - majority die,some die during pupal stage" "onion stage spermatid,Nebenkern derivative,spermatid axoneme,lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous,mesothoracic tergum" FBgn0037242 CG9855 - http://flybase.org/reports/FBgn0037242 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:26025 zinc ion binding ; GO:0008270 | inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:26025 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with HGNC:26025 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with HGNC:26025 CG9855 "IPR011016:Zinc finger, RING-CH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033275:E3 ubiquitin-protein ligase MARCH-like" CG9855 11-Aug-17 DroID_v2017_08 "Drer\march5l, Drer\march5" - Cele\M110.3 Xtro\march5 Mmus\March5 Hsap\MARCH5 viable FBgn0260123 2L1281 - http://flybase.org/reports/FBgn0260123 gene - - - 2L1281 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval epidermis,somatic clone" FBgn0266719 stac staccato http://flybase.org/reports/FBgn0266719 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "synaptic vesicle priming ; GO:0016082 | non-traceable author statement branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement" synaptic vesicle ; GO:0008021 | non-traceable author statement secretory vesicle ; GO:0099503 | inferred from direct assay "CG11819, CG34349, BP1013, CG34037, dunc-13-4B, unc-13-4B, stac, Unc-13-4B" "IPR000008:C2 domain, IPR014770:Munc13 homology 1, IPR014772:Mammalian uncoordinated homology 13, domain 2" CG34349 11-Aug-17 DroID_v2017_08 "Drer\unc13d, Drer\baiap3" - Cele\esyt-2 Xtro\baiap3 "Mmus\Unc13d, Mmus\Baiap3" "Hsap\UNC13D, Hsap\BAIAP3" FBgn0030847 CG12991 - http://flybase.org/reports/FBgn0030847 protein_coding_gene - - - CG12991 - CG12991 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0086473 l(3)EY09182 - http://flybase.org/reports/FBgn0086473 gene - - - l(3)EY09182 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069976 CG40473 - http://flybase.org/reports/FBgn0069976 protein_coding_gene - - - CG40473 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019673 mor(1)6 mortality gene (1)6 http://flybase.org/reports/FBgn0019673 - gene - - - mor(1)6 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0030518 CG11134 - http://flybase.org/reports/FBgn0030518 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence or structural similarity with UniProtKB:Q96GX9 methylthioribulose 1-phosphate dehydratase activity ; GO:0046570 | inferred from sequence or structural similarity with UniProtKB:Q96GX9 "L-methionine biosynthetic process from methylthioadenosine ; GO:0019509 | inferred from electronic annotation with InterPro:IPR017714, InterPro:IPR027514" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR017714, InterPro:IPR027514" "1, CG11134" "IPR001303:Class II aldolase/adducin N-terminal, IPR017714:Methylthioribulose-1-phosphate dehydratase, IPR027514:Methylthioribulose-1-phosphate dehydratase, eukaryotes" CG11134 11-Aug-17 DroID_v2017_08 Drer\apip Scer\MDE1 Cele\ZC373.5 Xtro\apip Mmus\Apip Hsap\APIP embryonic/larval hemocyte | third instar larval stage DRSC19384 E 0.859439463 1.2964004 1.86941592 -0.223484528 0.07425959 1.147245039 FBgn0044117 E(rst)C109 E(rst)C109 http://flybase.org/reports/FBgn0044117 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C109, E(rst)C109" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036550 CG17026 - http://flybase.org/reports/FBgn0036550 protein_coding_gene inositol monophosphate 1-phosphatase activity ; GO:0008934 | non-traceable author statement inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from sequence or structural similarity with HGNC:6051 inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550, InterPro:IPR020552 inositol phosphate dephosphorylation ; GO:0046855 | inferred from sequence or structural similarity with HGNC:6051 dephosphorylation ; GO:0016311 | non-traceable author statement inositol phosphate dephosphorylation ; GO:0046855 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol metabolic process ; GO:0006020 | inferred from biological aspect of ancestor with PANTHER:PTN000465134" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6051 "CG17026, cg17026" "IPR000760:Inositol monophosphatase-like, IPR033942:Inositol monophosphatase, IPR020550:Inositol monophosphatase, conserved site, IPR020552:Inositol monophosphatase, Lithium-sensitive, IPR020583:Inositol monophosphatase, metal-binding site" CG17026 11-Aug-17 DroID_v2017_08 "Drer\impa2, Drer\impa1" "Scer\INM2, Scer\INM1" Cele\ttx-7 "Xtro\impa1, Xtro\impa2" "Mmus\Impa2, Mmus\Impa1" "Hsap\IMPA2, Hsap\IMPA1" viable FBgn0029963 CG10920 - http://flybase.org/reports/FBgn0029963 protein_coding_gene - positive regulation of apoptotic process ; GO:0043065 | inferred from biological aspect of ancestor with PANTHER:PTN001324730 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001324730 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001324730 CG10920 "IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG10920 11-Aug-17 DroID_v2017_08 Drer\mtch2 "Scer\RIM2, Scer\YIA6" Cele\mtch-1 Xtro\mtch2 "Mmus\Mtch1, Mmus\Mtch2" "Hsap\MTCH1, Hsap\MTCH2" viable DRSC17765 K 0.589942067 -0.00125173 0.81691895 0.224616099 1.469723823 2.111677332 FBgn0039428 CG14237 - http://flybase.org/reports/FBgn0039428 protein_coding_gene - - - CG14237 - CG14237 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266366 CR45014 - http://flybase.org/reports/FBgn0266366 non_protein_coding_gene - - - CR45014 - CR45014 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026239 gukh GUK-holder http://flybase.org/reports/FBgn0026239 "FBgn0038668, FBgn0038669, FBgn0038670, FBgn0038671, FBgn0051043, FBgn0062172" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with dlg1 inferred from physical interaction with scrib actin cytoskeleton organization ; GO:0030036 | inferred from electronic annotation with InterPro:IPR028288 protein localization ; GO:0008104 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR028288 presynaptic membrane ; GO:0042734 | colocalizes_with inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay "Gukh, GUKh, CG6003, CG5456, CG14288, CG14287, CG31043, anon-WO0118547.205, gukh, GUKH, GukH" IPR028288:SCAR/WAVE family CG31043 11-Aug-17 DroID_v2017_08 "Drer\nhsa, Drer\wasf3b, Drer\si:ch73-362m14.4, Drer\nhsl1b, Drer\wasf2, Drer\wasf3a, Drer\nhsl2, Drer\wasf1, Drer\LOC101885310" - - "Xtro\wasf2, Xtro\wasf1" "Mmus\Wasf3, Mmus\Nhs, Mmus\Wasf2, Mmus\Wasf1" "Hsap\WASF1, Hsap\WASF3, Hsap\NHS, Hsap\NHSL1, Hsap\WASF2" "viable,neuroanatomy defective,somatic clone,lethal,recessive" FBgn0262095 CR42848 - http://flybase.org/reports/FBgn0262095 non_protein_coding_gene - - - "CG42848, CR42848" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039077 CG17380 - http://flybase.org/reports/FBgn0039077 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "BcDNA:AT18288, CG17380" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG17380 11-Aug-17 DroID_v2017_08 - - "Cele\tag-290, Cele\apl-1, Cele\K11D12.6" - "Mmus\Spint3, Mmus\Wfdc6a, Mmus\App" Hsap\APP viable FBgn0039473 CG17191 - http://flybase.org/reports/FBgn0039473 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG17191, DmelL4" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG17191 11-Aug-17 DroID_v2017_08 "Drer\lipg, Drer\lipia, Drer\lipca, Drer\lpl, Drer\LOC100331214, Drer\LOC101884800, Drer\pla1a, Drer\lipib" - - "Xtro\lipg, Xtro\lpl" "Mmus\Pnlip, Mmus\Pla1a, Mmus\Lipg, Mmus\Lpl, Mmus\Lipc, Mmus\Lipi, Mmus\Pnliprp1, Mmus\Pnliprp2, Mmus\Liph" "Hsap\PNLIPRP1, Hsap\LIPI, Hsap\PNLIPRP2, Hsap\PNLIPRP3, Hsap\LIPH, Hsap\PLA1A, Hsap\LPL, Hsap\LIPG, Hsap\PNLIP, Hsap\LIPC" FBgn0052229 CR32229 - http://flybase.org/reports/FBgn0052229 non_protein_coding_gene - - - CR32229 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039089 beat-IV beat-IV http://flybase.org/reports/FBgn0039089 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic - "beat IV, CG13823, CG10152, beat-IV, Beat-IV, beatIV" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG10152 11-Aug-17 DroID_v2017_08 - - - - - Hsap\CADM2 "oxidative stress response defective,partially lethal - majority die,some die during pupal stage" FBgn0061136 l(3)S001012 lethal (3) S001012 http://flybase.org/reports/FBgn0061136 gene - - - "0010/12, l(3)S001012" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260969 CG42592 - http://flybase.org/reports/FBgn0260969 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42592 IPR032145:Protein of unknown function DUF4818 CG42592 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001617 l(1)10Eb lethal (1) 10Eb http://flybase.org/reports/FBgn0001617 - gene - - - l(1)10Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0065055 snoRNA:Psi28S-2648 - http://flybase.org/reports/FBgn0065055 snoRNA_gene - - - "Dm-72, snoR72, CR33693, psi28s-2648 snoRNA, snoRNA:Psi28S-2648, psi28s-2648, snoRNA:72, Psi 28S-2648(SnoR72)" - CR33693 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032506 CG9395 - http://flybase.org/reports/FBgn0032506 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9395 IPR008166:Glycosyltransferase family 92 CG9395 11-Aug-17 DroID_v2017_08 "Drer\zgc:194839, Drer\si:zfos-464b6.2, Drer\si:dkey-56i24.1, Drer\si:ch73-211l2.1" - "Cele\ZK1025.4, Cele\ZK488.6, Cele\Y47D3B.4, Cele\K06H6.4, Cele\F54D10.8, Cele\C05C8.8, Cele\galt-1, Cele\K08D9.2, Cele\F36F12.3, Cele\D1014.5, Cele\Y105C5B.25, Cele\D1014.7, Cele\F46F5.7, Cele\R08C7.4, Cele\C14C6.6, Cele\C01G5.9, Cele\C14C6.8, Cele\F28H7.7, Cele\D1014.6, Cele\T15D6.10, Cele\C17A2.2, Cele\R05A10.6, Cele\T06A1.5, Cele\T05B11.4, Cele\C31B8.7, Cele\ZK488.5, Cele\T06A1.1, Cele\C08B6.3, Cele\C13A2.2" "Xtro\LOC100492375, Xtro\LOC100145503" - - viable DRSC03218 I 1.388632043 1.592936079 1.415024982 0.43074705 -0.848257943 -0.210018955 FBgn0010192 tu-mwh tu-mwh http://flybase.org/reports/FBgn0010192 - gene - - - tu-mwh - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval lymph gland FBgn0052206 CG32206 - http://flybase.org/reports/FBgn0052206 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG9600, CG14092, CG14091, CG14090, CG32206" "IPR000859:CUB domain, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG32206 11-Aug-17 DroID_v2017_08 Drer\f5 - "Cele\nas-8, Cele\nas-7, Cele\lev-10, Cele\nas-1" - Mmus\F5 Hsap\F5 "viable,fertile,visible" "chaeta,trichogen cell" FBgn0005737 l(1)TK226 lethal (1) TK226 http://flybase.org/reports/FBgn0005737 - gene - - - "l226, l(1)TK226" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0266033 CR44798 - http://flybase.org/reports/FBgn0266033 non_protein_coding_gene - - - CR44798 - CR44798 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000053 ade3 adenosine 3 http://flybase.org/reports/FBgn0000053 "FBgn0051628, FBgn0063628" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011761, InterPro:IPR013815, InterPro:IPR013816 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011761 phosphoribosylformylglycinamidine cyclo-ligase activity ; GO:0004641 | inferred from direct assay phosphoribosylglycinamide formyltransferase activity ; GO:0004644 | inferred from direct assay phosphoribosylamine-glycine ligase activity ; GO:0004637 | inferred from direct assay" "'de novo' IMP biosynthetic process ; GO:0006189 | inferred from electronic annotation with InterPro:IPR004607, InterPro:IPR004733 purine nucleobase biosynthetic process ; GO:0009113 | inferred from electronic annotation with InterPro:IPR000115, InterPro:IPR020559, InterPro:IPR020560, InterPro:IPR020562 purine nucleobase biosynthetic process ; GO:0009113 | inferred by curator from GO:0004637,GO:0004641,GO:0004644" cytosol ; GO:0005829 | inferred from direct assay "143062_at, Gart, GART, Gart/ade3, gart, D, ADE8, l(2)27Da, CG8761, CG31628, ade3, Ade3" "IPR013815:ATP-grasp fold, subdomain 1, IPR000115:Phosphoribosylglycinamide synthetase, IPR001555:Phosphoribosylglycinamide formyltransferase, active site, IPR002376:Formyl transferase, N-terminal, IPR004607:Phosphoribosylglycinamide formyltransferase, IPR004733:Phosphoribosylformylglycinamidine cyclo-ligase, IPR010918:AIR synthase-related protein, C-terminal domain, IPR011054:Rudiment single hybrid motif, IPR011761:ATP-grasp fold, IPR016185:Pre-ATP-grasp domain, IPR016188:PurM-like, N-terminal domain, IPR020559:Phosphoribosylglycinamide synthetase, conserved site, IPR020560:Phosphoribosylglycinamide synthetase, C-domain, IPR020561:Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain, IPR020562:Phosphoribosylglycinamide synthetase, N-terminal" CG31628 11-Aug-17 DroID_v2017_08 Drer\gart "Scer\ADE8, Scer\ADE5,7" Cele\F38B6.4 Xtro\gart Mmus\Gart Hsap\GART "auxotroph,recessive,lethal,visible,eye color defective,viable" "wing,wing vein,dorsal row,ventral row,trichome of the posterior wing margin,macrochaeta,tarsal segment,pigment cell" FBgn0017611 Gelatinase Gelatinase http://flybase.org/reports/FBgn0017611 - gene metalloendopeptidase activity ; GO:0004222 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available Gelatinase - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027161 l(2)KC-E l(2)Karp and Cherbas E http://flybase.org/reports/FBgn0027161 - gene - - - "E, l(2)KC-E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267172 CR45612 - http://flybase.org/reports/FBgn0267172 non_protein_coding_gene - - - CR45612 - CR45612 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001080 Fuc alpha Fucosidase http://flybase.org/reports/FBgn0001080 - gene - - - "a-FUC, alpha-FUC, Fuc, fuc, CG6128" - - 11-Aug-17 DroID_v2017_08 - - - - - - "electrophoretic variant,fertile,viable" FBgn0065646 l(2)SH0750 lethal (2) SH0750 http://flybase.org/reports/FBgn0065646 gene - - - "l(2)SH0750, l(2)SH2 0750" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038859 Obp93a Odorant-binding protein 93a http://flybase.org/reports/FBgn0038859 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "CG17284, Obp93a, DmelObp93a" IPR006170:Pheromone/general odorant binding protein CG17284 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026633 mys::tor mys::tor http://flybase.org/reports/FBgn0026633 - engineered_fusion_gene - - - mys::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "amnioserosa,dorsal ectoderm,wing" FBgn0067064 Nrt::wntD Nrt::wntD http://flybase.org/reports/FBgn0067064 engineered_fusion_gene - - - "Nrt::Wnt8, Nrt::wntD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044404 Scim23 Sensitized chromosome inheritance modifier 23 http://flybase.org/reports/FBgn0044404 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim23 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0025795 Su(var)502 Suppressor of variegation 502 http://flybase.org/reports/FBgn0025795 - gene - - - "Su-var(2)502, Su(var)502" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063779 s(3)4B s(3)4B http://flybase.org/reports/FBgn0063779 gene - - - s(3)4B - - 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,recessive" FBgn0065676 l(2)SH0675 lethal (2) SH0675 http://flybase.org/reports/FBgn0065676 gene - - - "l(2)SH0675, l(2)SH2 0675" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264641 dark-matter dark matter http://flybase.org/reports/FBgn0264641 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - dark-matter - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0039518 CG13978 - http://flybase.org/reports/FBgn0039518 protein_coding_gene mannose-ethanolamine phosphotransferase activity ; GO:0051377 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 CG13978 "IPR007070:GPI ethanolamine phosphate transferase 1, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR017852:GPI ethanolamine phosphate transferase 1, C-terminal, IPR002591:Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase" CG13978 11-Aug-17 DroID_v2017_08 Drer\pign Scer\MCD4 Cele\Y54E10BR.1 - Mmus\Pign "Hsap\PIGN, Hsap\ENPP4" viable FBgn0026739 anon-64Cb anon-64Cb http://flybase.org/reports/FBgn0026739 - gene - - - "gene c, anon-64Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036461 Zip71B Zinc/iron regulated transporter-related protein 71B http://flybase.org/reports/FBgn0036461 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred from biological aspect of ancestor with PANTHER:PTN000953562 cellular zinc ion homeostasis ; GO:0006882 | inferred from biological aspect of ancestor with PANTHER:PTN000953562 zinc II ion transmembrane import ; GO:0071578 | inferred from biological aspect of ancestor with PANTHER:PTN000953562 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000953562 "Zip71B, dZip71B, cg10006, CG10006" IPR003689:Zinc/iron permease CG10006 11-Aug-17 DroID_v2017_08 "Drer\slc39a10, Drer\slc39a5, Drer\slc39a4, Drer\slc39a7, Drer\slc39a8, Drer\slc39a6" Scer\YKE4 "Cele\tag-141, Cele\tag-140, Cele\Y55F3BL.2" "Xtro\slc39a6, Xtro\slc39a5, Xtro\slc39a12, Xtro\slc39a4, Xtro\slc39a7, Xtro\slc39a8, Xtro\slc39a10, Xtro\slc39a14" "Mmus\Slc39a14, Mmus\Slc39a10, Mmus\Slc39a7, Mmus\Slc39a6, Mmus\Slc39a12, Mmus\Slc39a5, Mmus\Slc39a8, Mmus\Slc39a4" "Hsap\SLC39A4, Hsap\SLC39A12, Hsap\SLC39A5, Hsap\SLC39A6, Hsap\SLC39A7, Hsap\SLC39A10, Hsap\SLC39A14, Hsap\SLC39A8" viable FBgn0004768 l(3)89Eg lethal (3) 89Eg http://flybase.org/reports/FBgn0004768 - gene - - - l(3)89Eg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264340 CG43796 - http://flybase.org/reports/FBgn0264340 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43796 - CG43796 11-Aug-17 DroID_v2017_08 "Drer\LOC100006122, Drer\rasip1, Drer\myo5b, Drer\radil, Drer\myo5c, Drer\si:dkey-110c1.10, Drer\myo19, Drer\myo5aa, Drer\myo5ab" - - "Xtro\myo5a, Xtro\myo19, Xtro\rasip1" "Mmus\Myo5c, Mmus\Myo1g, Mmus\Iqcb1, Mmus\Rasip1, Mmus\Myo19, Mmus\Myh10, Mmus\Myo5b, Mmus\Myo5a" "Hsap\RASIP1, Hsap\MYO5B, Hsap\MYO5C, Hsap\IQCB1, Hsap\MYO5A, Hsap\MYO19, Hsap\MYO1G" FBgn0047299 CG31535 - http://flybase.org/reports/FBgn0047299 protein_coding_gene - - - "BcDNA:GH26355, CG31535" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034351 rswl roswell http://flybase.org/reports/FBgn0034351 protein_coding_gene - mitochondrial tRNA processing ; GO:0090646 | inferred from mutant phenotype ATP metabolic process ; GO:0046034 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "CG5190, rswl, MRPP1" "IPR025812:Mitochondrial ribonuclease P protein 1, IPR007356:tRNA (guanine-N1-)-methyltransferase, eukaryotic, IPR016009:tRNA methyltransferase TRMD/TRM10-type domain, IPR028564:tRNA methyltransferase TRM10-type domain" CG5190 11-Aug-17 DroID_v2017_08 "Drer\trmt10a, Drer\trmt10b, Drer\trmt10c" Scer\TRM10 "Cele\C56G2.3, Cele\F25H8.1, Cele\F46F11.10, Cele\C37A5.7" "Xtro\trmt10a, Xtro\trmt10c" "Mmus\Trmt10a, Mmus\Trmt10c, Mmus\Trmt10b" "Hsap\TRMT10C, Hsap\TRMT10B, Hsap\TRMT10A" "viable,visible" trichogen cell FBgn0060361 l(3)S139213 lethal (3) S139213 http://flybase.org/reports/FBgn0060361 gene - - - "1392/13, l(3)S139213" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003025 ove over-etherised http://flybase.org/reports/FBgn0003025 - gene - - - ove - - 11-Aug-17 DroID_v2017_08 - - - - - - uncoordinated FBgn0004908 Arl2 ADP ribosylation factor-like 2 http://flybase.org/reports/FBgn0004908 - protein_coding_gene GTP binding ; GO:0005525 | inferred from sequence or structural similarity with HGNC:693 inferred from sequence model GTPase activity ; GO:0003924 | inferred from sequence or structural similarity small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 neurotransmitter secretion ; GO:0007269 | traceable author statement synaptic vesicle endocytosis ; GO:0048488 | traceable author statement microtubule cytoskeleton organization involved in mitosis ; GO:1902850 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype endosomal transport ; GO:0016197 | traceable author statement establishment or maintenance of neuroblast polarity ; GO:0045196 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR024156 cellular_component ; GO:0005575 | no biological data available "Dm Arf84F, Arf, Q06849, Arf84D, CG7435, Arl84F, arl2, Arl2, Arf84F, CG 7435, ARL2" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR024156:Small GTPase superfamily, ARF type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7435 11-Aug-17 DroID_v2017_08 "Drer\arl2, Drer\arl13a, Drer\arl3, Drer\arl3l1, Drer\zgc:110197" "Scer\ARF2, Scer\CIN4" "Cele\arl-3, Cele\ifta-2, Cele\evl-20" "Xtro\arl3.2, Xtro\arl3.1, Xtro\arl13a, Xtro\arl2" "Mmus\Arl3, Mmus\Arl2, Mmus\Arl13a" "Hsap\ARL3, Hsap\ARL2, Hsap\ARL13A" embryonic stage -- adult stage "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0026592 Fie Fire exit http://flybase.org/reports/FBgn0026592 FBgn0035467 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model "HL04053, BEST:HL04053, Fie, CG1079" IPR031720:Protein of unknown function DUF4728 CG1079 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially lethal - majority die,visible,wild-type,fertile" "tarsal segment,trichome,eye" FBgn0266042 CR44807 - http://flybase.org/reports/FBgn0266042 non_protein_coding_gene - - - CR44807 - CR44807 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028252 l(3)87Ce lethal (3) 87Ce http://flybase.org/reports/FBgn0028252 gene - - - l(3)87Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032198 eEF1delta eukaryotic translation elongation factor 1 delta http://flybase.org/reports/FBgn0032198 protein_coding_gene "translation elongation factor activity ; GO:0003746 | inferred from electronic annotation with InterPro:IPR001326, InterPro:IPR014038 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity" "translational elongation ; GO:0006414 | inferred from electronic annotation with InterPro:IPR001326, InterPro:IPR014038 translational elongation ; GO:0006414 | inferred from sequence or structural similarity" "eukaryotic translation elongation factor 1 complex ; GO:0005853 | inferred from electronic annotation with InterPro:IPR001326, InterPro:IPR014038 eukaryotic translation elongation factor 1 complex ; GO:0005853 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay" "eEF1delta, CG4912, eEF1d, eEf1delta" "IPR001326:Translation elongation factor EF1B, beta/delta chains, conserved site, IPR014038:Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain, IPR014717:Translation elongation factor EF1B/ribosomal protein S6, IPR018940:Elongation factor 1 beta central acidic region, eukaryote" CG4912 11-Aug-17 DroID_v2017_08 "Drer\eef1db, Drer\eef1da, Drer\eef1b2" Scer\EFB1 "Cele\eef-1B.1, Cele\eef-1B.2" "Xtro\eef1b2, Xtro\eef1d" "Mmus\Eef1b2, Mmus\Eef1d" "Hsap\EEF1B2, Hsap\EEF1D" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0016034 mael maelstrom http://flybase.org/reports/FBgn0016034 - protein_coding_gene transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay "oogenesis ; GO:0048477 | inferred from mutant phenotype piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype pole plasm mRNA localization ; GO:0019094 | non-traceable author statement germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype oocyte fate commitment ; GO:0048600 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | traceable author statement gene silencing by RNA ; GO:0031047 | inferred from mutant phenotype oocyte nucleus migration involved in oocyte dorsal/ventral axis specification ; GO:0007312 | inferred from mutant phenotype regulation of gene silencing by miRNA ; GO:0060964 | inferred from direct assay dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype miRNA metabolic process ; GO:0010586 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | traceable author statement microtubule organizing center organization ; GO:0031023 | inferred from mutant phenotype piRNA metabolic process ; GO:0034587 | inferred from biological aspect of ancestor with PANTHER:PTN001849055 male meiosis ; GO:0007140 | inferred from biological aspect of ancestor with PANTHER:PTN001849055" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "CG11254, mael, Mael, mae1, MAEL" "IPR024970:Maelstrom domain, IPR009071:High mobility group box domain" CG11254 11-Aug-17 DroID_v2017_08 - - - Xtro\mael Mmus\Mael Hsap\MAEL " adult stage && oogenesis stage | stage S1-8 , adult stage | female && oogenesis stage " " nurse cell

, germarium && germline cell

" "female sterile,male sterile,sterile,wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,female semi-sterile" "dorsal appendage,germline clone,maternal effect,male germline cell,male germline cyst,spermatocyte ring canal,male germline stem cell,ectopic,female germline stem cell,supernumerary,cystoblast,germarium region 3,germline cell,egg chamber,ovary,karyosome,oocyte & microtubule,oocyte & centriole79E-F),oocyte & microtubule organizing center79E-F),chorion | germline clone,oocyte,follicle cell,microtubule & oocyte" FBgn0004092 l(2)60Cd lethal (2) 60Cd http://flybase.org/reports/FBgn0004092 - gene - - - l(2)60Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0032088 CG13102 - http://flybase.org/reports/FBgn0032088 protein_coding_gene - - - "BcDNA:RE57454, CG13102" - CG13102 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016889 l(2)39DEn lethal (2) 39DEn http://flybase.org/reports/FBgn0016889 - gene - - - "L110, l(2)39DEn" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002603 M(2)53 Minute (2) 53 http://flybase.org/reports/FBgn0002603 - gene - - - "M(2)53-1, M(2)53C, M(2)S-7, M(2)S7, M(2R)S7, M(2)53" - - 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,dominant,visible,Minute,small body" macrochaeta FBgn0033428 Updo Updo http://flybase.org/reports/FBgn0033428 protein_coding_gene uroporphyrinogen decarboxylase activity ; GO:0004853 | inferred from biological aspect of ancestor with PANTHER:PTN000472797 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000472797 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000472797 "CG1818, Updo" "IPR000257:Uroporphyrinogen decarboxylase (URO-D), IPR006361:Uroporphyrinogen decarboxylase HemE" CG1818 11-Aug-17 DroID_v2017_08 Drer\urod Scer\HEM12 - Xtro\urod Mmus\Urod Hsap\UROD DRSC30007 K -0.858619708 -0.28628326 -0.014652526 -0.062674511 1.553191606 2.34894202 FBgn0033808 CG4627 - http://flybase.org/reports/FBgn0033808 protein_coding_gene - - - CG4627 IPR026571:Transmembrane protein 186 CG4627 11-Aug-17 DroID_v2017_08 Drer\tmem186 - - - Mmus\Tmem186 Hsap\TMEM186 "partially lethal - majority die,some die during pupal stage" FBgn0063392 snoRNA:U14:30Ea snoRNA:U14:30Ea http://flybase.org/reports/FBgn0063392 snoRNA_gene - - - "Dm-396, U14snoRNA, snoRNA:U14:a, CR32875, snoRNA:U14:30Ea, DmU14a(U14), chr2L:9894175..9894283, U14:30Ea" - CR32875 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053384 5SrRNA:CR33384 5SrRNA:CR33384 http://flybase.org/reports/FBgn0053384 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33384, 5SrRNA:CR33384" - CR33384 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020825 l(3)98Da lethal (3) 98Da http://flybase.org/reports/FBgn0020825 - gene - - - "M313, l(3)M3-13, l(3)98D-Ea, l(3)98Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065163 l(3)SH039 lethal (3) SH039 http://flybase.org/reports/FBgn0065163 gene - - - "l(3)SH039, l(2)SH3 039" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004025 wt welt http://flybase.org/reports/FBgn0004025 - gene - - - wt - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,macrochaeta,postvertical bristle,abdomen,wing,eye disc,wing disc" FBgn0052762 CG32762 - http://flybase.org/reports/FBgn0052762 protein_coding_gene - - - CG32762 - CG32762 11-Aug-17 DroID_v2017_08 "Drer\phex, Drer\mmel1, Drer\ece2b, Drer\ece1" - - "Xtro\mmel1, Xtro\ece2, Xtro\ecel1, Xtro\ece1" "Mmus\Ece1, Mmus\Mme, Mmus\Kel, Mmus\Phex, Mmus\Ece2, Mmus\Mmel1, Mmus\Ecel1" "Hsap\PHEX, Hsap\ECEL1, Hsap\MME, Hsap\MMEL1, Hsap\ECE2, Hsap\KEL, Hsap\ECE1" DRSC18298 I 1.782959867 -0.168214914 0.760168683 0.330907505 -0.188345434 -0.276319349 FBgn0025513 fs(3)82EFc fs(3)82EFc http://flybase.org/reports/FBgn0025513 - gene - - - fs(3)82EFc - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0061114 l(3)S005912 lethal (3) S005912 http://flybase.org/reports/FBgn0061114 gene - - - "0059/12, l(3)S005912" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0067058 P61 P61 http://flybase.org/reports/FBgn0067058 gene - - - P61 - - 11-Aug-17 DroID_v2017_08 - - - - - - neurophysiology defective FBgn0024756 EC91 EC91 http://flybase.org/reports/FBgn0024756 - gene - - - EC91 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,female,non-enhancer of variegation,male" FBgn0266750 CR45223 - http://flybase.org/reports/FBgn0266750 non_protein_coding_gene - - - CR45223 - CR45223 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052073 CG32073 - http://flybase.org/reports/FBgn0052073 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32073 - CG32073 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011211 blw bellwether http://flybase.org/reports/FBgn0011211 "FBgn0010487, FBgn0010561, FBgn0011298, FBgn0022274" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | inferred from sequence or structural similarity with MGI:MGI:88115" electron transport chain ; GO:0022900 | inferred from direct assay spermatid development ; GO:0007286 | inferred from mutant phenotype regulation of choline O-acetyltransferase activity ; GO:1902769 | inferred from direct assay growth ; GO:0040007 | inferred from mutant phenotype proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P25705 ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000000195 lipid storage ; GO:0019915 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype "mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P25705 microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay" "blw, l(2)k00212, CG3612, A2(2nd)27, ATPsyn-alpha, l(2)59ABa, ms(2)Pry58F, ms(2)01504, l(2)03972, l(2)01410, ATP5a, C-V-alpha, Blw, CValpha, ATPA_DROME, CxV, ATPA, ATPsynalpha, ATP syn-alpha, C-Va, ATP5A" "IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR000793:ATP synthase, alpha subunit, C-terminal, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005294:ATP synthase, F1 complex, alpha subunit, IPR023366:ATP synthase subunit alpha-like domain, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033732:ATP synthase, F1 complex, alpha subunit nucleotide-binding domain" CG3612 11-Aug-17 DroID_v2017_08 Drer\atp5a1 Scer\ATP1 "Cele\T26E3.7, Cele\H28O16.1" Xtro\atp5a1 Mmus\Atp5a1 Hsap\ATP5A1 larval stage | third instar dorsal mesothoracic disc

"male sterile,recessive,viable,fertile,lethal,mitotic cell cycle defective,cell autonomous,decreased cell size,somatic clone,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,visible" "wing disc,cell autonomous,somatic clone,mesothoracic tergum" DRSC04675 K -0.410897119 0.230155598 -1.369506692 -0.017553756 1.761256119 2.056332329 FBgn0011028 l(3)s2500 lethal (3) s2500 http://flybase.org/reports/FBgn0011028 - gene - - - l(3)s2500 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031099 CG17065 - http://flybase.org/reports/FBgn0031099 protein_coding_gene N-acetylglucosamine-6-phosphate deacetylase activity ; GO:0008448 | inferred from electronic annotation with InterPro:IPR003764 N-acetylglucosamine metabolic process ; GO:0006044 | inferred from electronic annotation with InterPro:IPR003764 cellular_component ; GO:0005575 | no biological data available CG17065 "IPR003764:N-acetylglucosamine-6-phosphate deacetylase, IPR006680:Amidohydrolase-related, IPR011059:Metal-dependent hydrolase, composite domain, IPR032466:Metal-dependent hydrolase" CG17065 11-Aug-17 DroID_v2017_08 Drer\amdhd2 - Cele\F59B2.3 Xtro\amdhd2 Mmus\Amdhd2 Hsap\AMDHD2 "viable,fertile,partially lethal - majority die" FBgn0024258 acd(2)5N18 auditory courtship defective 5N18 http://flybase.org/reports/FBgn0024258 - gene molecular_function ; GO:0003674 | no biological data available adult walking behavior ; GO:0007628 | inferred from mutant phenotype auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5N18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective,smell perception defective" adult brain FBgn0266143 CR44849 - http://flybase.org/reports/FBgn0266143 non_protein_coding_gene - - - CR44849 - CR44849 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036065 CG14161 - http://flybase.org/reports/FBgn0036065 protein_coding_gene - - - CG14161 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051072 Lerp lysosomal enzyme receptor protein http://flybase.org/reports/FBgn0051072 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR000479 protein binding ; GO:0005515 | inferred from physical interaction with Gga positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype post-Golgi vesicle-mediated transport ; GO:0006892 | inferred from direct assay lysosomal transport ; GO:0007041 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000479 clathrin-coated vesicle ; GO:0030136 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytoplasm ; GO:0005737 | inferred by curator from GO:0007041 trans-Golgi network ; GO:0005802 | inferred from direct assay "CG31072, LERP, CG6396, CG14255, CG14256, CG6390, anon-WO0118547.383, Lerp" "IPR000479:Cation-independent mannose-6-phosphate receptor, IPR009011:Mannose-6-phosphate receptor binding domain" CG31072 11-Aug-17 DroID_v2017_08 "Drer\igf2r, Drer\fn1a, Drer\fn1b, Drer\m6pr" Scer\MRL1 Cele\F31B9.4 "Xtro\fn1, Xtro\igf2r" "Mmus\Igf2r, Mmus\Bsph2, Mmus\M6pr, Mmus\Bsph1, Mmus\Fn1" "Hsap\FN1, Hsap\ELSPBP1, Hsap\IGF2R, Hsap\BSPH1" "viable,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0001845 l(1)ts2864 lethal (1) ts2864 http://flybase.org/reports/FBgn0001845 - gene - - - l(1)ts2864 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0063403 l(3)CG4 lethal (3) CG4 http://flybase.org/reports/FBgn0063403 gene - - - l(3)CG4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011049 l(1)Q2 lethal (1) Q2 http://flybase.org/reports/FBgn0011049 FBgn0010210 gene - - - l(1)Q2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033856 CG13334 - http://flybase.org/reports/FBgn0033856 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR001557, InterPro:IPR015955, InterPro:IPR022383" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR015955 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001236, InterPro:IPR001557, InterPro:IPR015955, InterPro:IPR022383 carboxylic acid metabolic process ; GO:0019752 | inferred from electronic annotation with InterPro:IPR001557" - "NEST:bs27e02, CG13334" "IPR001236:Lactate/malate dehydrogenase, N-terminal, IPR001557:L-lactate/malate dehydrogenase, IPR015955:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR016040:NAD(P)-binding domain, IPR022383:Lactate/malate dehydrogenase, C-terminal" CG13334 11-Aug-17 DroID_v2017_08 "Drer\uevld, Drer\ldhba, Drer\ldhbb, Drer\ldha" Scer\MDH3 Cele\ldh-1 "Xtro\uevld, Xtro\ldhb, Xtro\ldha" "Mmus\Ldhc, Mmus\Ldhb, Mmus\Ldha, Mmus\Uevld, Mmus\Ldhal6b" "Hsap\UEVLD, Hsap\LDHA, Hsap\LDHC, Hsap\LDHAL6A, Hsap\LDHAL6B, Hsap\LDHB" viable FBgn0037456 CG1138 - http://flybase.org/reports/FBgn0037456 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG1138 IPR031883:Protein of unknown function DUF4763 CG1138 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267219 CR45659 - http://flybase.org/reports/FBgn0267219 non_protein_coding_gene - - - "CR45659, lincRNA.655" - CR45659 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031813 CG9527 - http://flybase.org/reports/FBgn0031813 protein_coding_gene acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012258 acyl-CoA oxidase activity ; GO:0003997 | inferred from sequence or structural similarity with HGNC:119 phagocytosis ; GO:0006909 | inferred from mutant phenotype fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:119 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:121 inferred from sequence model "CG9527, LCAD" "IPR002655:Acyl-CoA oxidase, C-terminal, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR012258:Acyl-CoA oxidase, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal" CG9527 11-Aug-17 DroID_v2017_08 "Drer\acox1, Drer\acox3, Drer\acoxl" Scer\POX1 Cele\acox-6 "Xtro\acox1, Xtro\acox3, Xtro\acox2" "Mmus\Acox3, Mmus\Acox2, Mmus\Acoxl, Mmus\Acox1" "Hsap\ACOX2, Hsap\ACOXL, Hsap\ACOX1, Hsap\ACOX3" viable FBgn0035409 CG14963 - http://flybase.org/reports/FBgn0035409 protein_coding_gene - - - CG14963 IPR010629:Insect allergen-related CG14963 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032656 CG5674 - http://flybase.org/reports/FBgn0032656 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG5674 - CG5674 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0060376 l(3)SzB90Cn lethal (3) SzB90Cn http://flybase.org/reports/FBgn0060376 gene - - - "1357/07, l(3)S135707b, l(3)SzB90Cn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069362 MTIP motif 2 interacting protein http://flybase.org/reports/FBgn0069362 gene - - - MTIP - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036601 CG13063 - http://flybase.org/reports/FBgn0036601 protein_coding_gene - - - CG13063 IPR007614:Retinin-like protein CG13063 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266140 CR44846 - http://flybase.org/reports/FBgn0266140 non_protein_coding_gene - - - CR44846 - CR44846 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066119 EP3219 EP3219 http://flybase.org/reports/FBgn0066119 gene - - - EP3219 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,small body,female sterile,decreased cell size" FBgn0014053 Su(tor)2-321 Su(tor)2-321 http://flybase.org/reports/FBgn0014053 - gene - - - Su(tor)2-321 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0032370 CG12307 - http://flybase.org/reports/FBgn0032370 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12307 - CG12307 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028656 anon-35F-36Aa anon-35F-36Aa http://flybase.org/reports/FBgn0028656 gene - - - "anon-35F/36Aa, anon-35F-36Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052482 tRNA:iMet-CAT-1-3 transfer RNA:initiator Methionine-CAT 1-3 http://flybase.org/reports/FBgn0052482 tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "tRNA[[i]][Met], AE002584.trna21-MetCAT, tRNA:met3:61Dg, tRNA:met3:61Df, tRNA:met3:61De, tRNA:met3:61Dd, tRNA:met-i:61Db, tRNA:met-i:61Da, tRNA:met-i, tRNA:M3:61Dg, tRNA:M3:61Df, tRNA:M3:61De, tRNA:M3:61Dd, tRNA:M-i:61Db, tRNA:M-i:61Da, tRNA:M-i, tRNA:M:CAT:AE002584-b, CR32482, tRNA[Met-ATG], chr3L.trna49-MetCAT, RNA:M-i:61D, tRNA-iMet-CAT-1-3, tRNA:iMet-CAT-1-3, tRNA:M-i:61D" - CR32482 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,large body" FBgn0264378 CR43830 - http://flybase.org/reports/FBgn0264378 non_protein_coding_gene - - - "CR43830, lincRNA.311" - CR43830 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035987 CG3689 - http://flybase.org/reports/FBgn0035987 protein_coding_gene "mRNA binding ; GO:0003729 | inferred from electronic annotation with InterPro:IPR016706 hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797" mRNA polyadenylation ; GO:0006378 | inferred from electronic annotation with InterPro:IPR016706 mRNA cleavage factor complex ; GO:0005849 | inferred from electronic annotation with InterPro:IPR016706 "CG3689, CF I[[m]]25" "IPR000086:NUDIX hydrolase domain, IPR016706:Cleavage/polyadenylation specificity factor subunit 5, IPR015797:NUDIX hydrolase domain-like" CG3689 11-Aug-17 DroID_v2017_08 Drer\nudt21 - Cele\cfim-1 Xtro\nudt21 Mmus\Nudt21 Hsap\NUDT21 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,tormogen cell,mesothoracic tergum" FBgn0003354 sens(3)str sensitive to streptomycin http://flybase.org/reports/FBgn0003354 - gene - - - "str[s], sens(3)str" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0060758 l(3)S063811 lethal (3) S063811 http://flybase.org/reports/FBgn0060758 gene - - - "0638/11, l(3)S063811" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0265839 CR44628 - http://flybase.org/reports/FBgn0265839 non_protein_coding_gene - - - CR44628 - CR44628 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033588 CG13228 - http://flybase.org/reports/FBgn0033588 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13228 - CG13228 11-Aug-17 DroID_v2017_08 - - Cele\F12A10.7 - - - viable FBgn0001946 l(2)27Ca lethal (2) 27Ca http://flybase.org/reports/FBgn0001946 - gene - - - "A, l(2)27Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028903 CG13243 - http://flybase.org/reports/FBgn0028903 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "BG:DS02252.1, CG13243" "IPR003117:cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain" CG13243 11-Aug-17 DroID_v2017_08 Drer\catip - - Xtro\catip Mmus\Catip Hsap\CATIP "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0016864 l(2)39ADb lethal (2) 39ADb http://flybase.org/reports/FBgn0016864 - gene - - - "J50, l(2)39ADb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030483 CG12725 - http://flybase.org/reports/FBgn0030483 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12725 "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG12725 11-Aug-17 DroID_v2017_08 Drer\ubb - - - Mmus\Rps27a Hsap\UBB viable FBgn0262327 mir-2281 mir-2281 stem loop http://flybase.org/reports/FBgn0262327 miRNA_gene - - - "mir-2281, CR43034, miR-2281, dme-mir-2281" - CR43034 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028251 l(3)90Ea lethal (3) 90Ea http://flybase.org/reports/FBgn0028251 gene - - - l(3)90Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003128 port-b port b http://flybase.org/reports/FBgn0003128 - gene - - - port-b - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective" pigment cell FBgn0038425 CG14881 - http://flybase.org/reports/FBgn0038425 protein_coding_gene - - - CG14881 "IPR002539:MaoC-like domain, IPR016024:Armadillo-type fold, IPR029069:HotDog domain, IPR011989:Armadillo-like helical" CG14881 11-Aug-17 DroID_v2017_08 "Drer\hsd17b4, Drer\armc7" Scer\FOX2 - Xtro\hsd17b4 "Mmus\Hsd17b4, Mmus\Armc7" "Hsap\ARMC7, Hsap\RPP14, Hsap\HSD17B4" viable FBgn0260970 Ubr3 Ubr3 ubiquitin ligase http://flybase.org/reports/FBgn0260970 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR003126 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay" protein autoubiquitination ; GO:0051865 | inferred from direct assay ubiquitin-dependent protein catabolic process via the N-end rule pathway ; GO:0071596 | inferred from biological aspect of ancestor with PANTHER:PTN000486924 positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype positive regulation of MyD88-dependent toll-like receptor signaling pathway ; GO:0034126 | inferred from mutant phenotype protein K48-linked ubiquitination ; GO:0070936 | inferred from direct assay negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from mutant phenotype ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000486924 cytosol ; GO:0005829 | inferred from direct assay "Ubr3, ubr3, CG42593, CG1531, CG1530, UBR3" "IPR003126:Zinc finger, UBR-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG42593 11-Aug-17 DroID_v2017_08 Drer\ubr3 "Scer\UBR1, Scer\UBR2" Cele\F10G7.10 Xtro\ubr3 Mmus\Ubr3 Hsap\UBR3 FBgn0031822 Phf5a PHD finger protein 5a http://flybase.org/reports/FBgn0031822 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:18000 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with HGNC:18000 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000319347 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000319347 U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000319347 "BcDNA:RH02789, CG9548, Phf5a, PHF5A" IPR005345:PHF5-like CG9548 11-Aug-17 DroID_v2017_08 Drer\phf5a Scer\RDS3 "Cele\Y54F10BM.1, Cele\phf-5" Xtro\phf5a Mmus\Phf5a Hsap\PHF5A "lethal - all die before end of pupal stage,some die during pupal stage,female fertile" DRSC03261 I -0.257919123 1.945898208 0.022653043 0.447401283 0.499423496 -0.531294774 FBgn0037746 CG8478 - http://flybase.org/reports/FBgn0037746 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG8478 IPR013087:Zinc finger C2H2-type CG8478 11-Aug-17 DroID_v2017_08 "Drer\znf1016, Drer\zbtb47b, Drer\znf1008, Drer\znf982, Drer\zgc:66472, Drer\si:ch211-266d19.4, Drer\znf646, Drer\znf652, Drer\znf526, Drer\znf983, Drer\znf990, Drer\si:dkey-89b17.4, Drer\zbtb37, Drer\znf1035, Drer\LOC103910265, Drer\zbtb34, Drer\zbtb47a, Drer\znf1010" Scer\RME1 - - "Mmus\Zbtb37, Mmus\Zbtb34, Mmus\Zfp748, Mmus\Zfp30, Mmus\Zfp526, Mmus\Zfp619, Mmus\Zfp788, Mmus\Zfp764, Mmus\Zfp652, Mmus\Zfp759, Mmus\Zfp738, Mmus\Zbtb1, Mmus\Zfp553, Mmus\Zfp457, Mmus\Zfp953, Mmus\Zfp458, Mmus\Zfp651, Mmus\Zfp689, Mmus\Zfp459, Mmus\Zfp282, Mmus\Gm14295, Mmus\Zfp92, Mmus\Zfp65, Mmus\Zfp74, Mmus\Zfp658, Mmus\Zfp324, Mmus\Zfp771" "Hsap\ZNF208, Hsap\ZNF99, Hsap\ZNF785, Hsap\ZNF84, Hsap\ZNF665, Hsap\ZNF160, Hsap\ZNF850, Hsap\ZNF845, Hsap\ZNF497, Hsap\ZNF771, Hsap\ZNF347, Hsap\ZBTB47, Hsap\ZFP92, Hsap\ZNF764, Hsap\ZNF594, Hsap\ZBTB1, Hsap\ZNF473, Hsap\ZNF324, Hsap\ZNF689, Hsap\ZNF526, Hsap\ZNF184, Hsap\ZNF48, Hsap\ZNF282, Hsap\ZNF324B, Hsap\ZNF805, Hsap\ZBTB37, Hsap\ZNF729, Hsap\ZNF107, Hsap\ZBTB34, Hsap\ZNF569, Hsap\ZNF354B, Hsap\ZNF91, Hsap\ZNF264, Hsap\ZNF652" viable FBgn0044103 E(rst)C45 E(rst)C45 http://flybase.org/reports/FBgn0044103 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C45, E(rst)C45" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0069443 E(br)72 E(br)72 http://flybase.org/reports/FBgn0069443 gene - - - E(br)72 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0267490 Mst77Y-4 Male-specific transcript 77Y 4 http://flybase.org/reports/FBgn0267490 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F "Mst77Y-4, CG45763, Mst77Y-4a, MST77Y" - CG45763 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035811 CG12262 - http://flybase.org/reports/FBgn0035811 protein_coding_gene medium-chain-acyl-CoA dehydrogenase activity ; GO:0070991 | inferred from electronic annotation with InterPro:IPR034180 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786 acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from sequence or structural similarity with UniProtKB:P11310 fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with UniProtKB:P11310 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG12262, CG 12262, ACAD, MCAD" "IPR006089:Acyl-CoA dehydrogenase, conserved site, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR034180:Medium-chain specific acyl-CoA dehydrogenase" CG12262 11-Aug-17 DroID_v2017_08 "Drer\acadm, Drer\acads, Drer\acad8, Drer\acad9, Drer\acadvl" - "Cele\acdh-8, Cele\acdh-7, Cele\acdh-1, Cele\acdh-4, Cele\acdh-10, Cele\acdh-9" "Xtro\acadsb, Xtro\acad9, Xtro\ivd, Xtro\acads, Xtro\acad8, Xtro\acadm" "Mmus\Acadm, Mmus\Acad8, Mmus\Acadvl, Mmus\Acads, Mmus\Acad9, Mmus\Acadsb, Mmus\Ivd" "Hsap\IVD, Hsap\ACAD9, Hsap\ACAD8, Hsap\ACADS, Hsap\ACADVL, Hsap\ACADSB, Hsap\ACADM" viable FBgn0022807 E(faf)bE365 Enhancer of faf bE365 http://flybase.org/reports/FBgn0022807 - gene - - - E(faf)bE365 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038694 CG5217 - http://flybase.org/reports/FBgn0038694 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.188, CG5217" - CG5217 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0067744 l(1)G0275 lethal (1) G0275 http://flybase.org/reports/FBgn0067744 gene - - - l(1)G0275 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0085709 CG41584 - http://flybase.org/reports/FBgn0085709 protein_coding_gene - - - CG41584 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011232 scat scattered http://flybase.org/reports/FBgn0011232 FBgn0032118 protein_coding_gene syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000311465 "Golgi to vacuole transport ; GO:0006896 | inferred from sequence or structural similarity with UniProtKB:Q12071 Golgi to vacuole transport ; GO:0006896 | inferred from biological aspect of ancestor with PANTHER:PTN000311465 spermatid nucleus elongation ; GO:0007290 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from direct assay acrosome assembly ; GO:0001675 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN000311465 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with UniProtKB:Q12071" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q12071 GARP complex ; GO:0000938 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with UniProtKB:Q12071 GARP complex ; GO:0000938 | inferred from sequence or structural similarity with HGNC:18652 Golgi trans cisterna ; GO:0000138 | inferred from direct assay "CG3766, ms(2)30B, ms(2)05289, scat, Vps54, Scat" "IPR012501:Vps54-likeVacuolar protein sorting-associated protein 54, C-terminal, IPR019515:Vacuolar protein sorting-associated protein 54, N-terminal" CG3766 11-Aug-17 DroID_v2017_08 Drer\vps54 Scer\VPS54 Cele\vps-54 Xtro\vps54 Mmus\Vps54 Hsap\VPS54 "male sterile,recessive,partially lethal - majority die,viable,fertile" "spermatozoon,primary spermatocyte cyst,spermatid" FBgn0010815 l(3)03719 lethal (3) 03719 http://flybase.org/reports/FBgn0010815 FBgn0011345 gene molecular_function ; GO:0003674 | no biological data available periodic partitioning ; GO:0007365 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(3)j3B3, l(3)03719" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect" "embryonic/first instar larval cuticle,maternal effect,segment" FBgn0060351 l(3)S142206 lethal (3) S142206 http://flybase.org/reports/FBgn0060351 gene - - - "1422/06, l(3)S142206" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267240 CR45680 - http://flybase.org/reports/FBgn0267240 non_protein_coding_gene - - - CR45680 - CR45680 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033194 Vps13 Vacuolar protein sorting 13 http://flybase.org/reports/FBgn0033194 protein_coding_gene - protein targeting to vacuole ; GO:0006623 | inferred from sequence or structural similarity with SGD:S000003963 - "BEST:LD02743, Vps13, CG2093" "IPR009543:Vacuolar protein sorting-associated protein 13, SHR-binding domain, IPR026847:Vacuolar protein sorting-associated protein 13, IPR026854:Vacuolar protein sorting-associated protein 13, N-terminal domain, IPR031642:VPS13, repeated coiled region, IPR031646:Vacuolar protein sorting-associated protein 13, second N-terminal domain, IPR031645:Vacuolar protein sorting-associated protein 13, C-terminal" CG2093 11-Aug-17 DroID_v2017_08 "Drer\LOC101882151, Drer\vps13a, Drer\vps13d, Drer\vps13c" Scer\VPS13 "Cele\C25H3.11, Cele\T08G11.1, Cele\C25H3.8" "Xtro\vps13a, Xtro\vps13b" "Mmus\Vps13b, Mmus\Vps13a, Mmus\Vps13d, Mmus\Vps13c" "Hsap\VPS13D, Hsap\VPS13A, Hsap\VPS13B, Hsap\VPS13C" viable FBgn0035969 CG4476 - http://flybase.org/reports/FBgn0035969 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model amino acid transmembrane import ; GO:0044745 | inferred from sequence model transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 visual behavior ; GO:0007632 | inferred from mutant phenotype neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay "anon-WO0149848.7, CG4476, DmNAT3" IPR000175:Sodium:neurotransmitter symporter CG4476 11-Aug-17 DroID_v2017_08 "Drer\slc6a16b, Drer\slc6a5, Drer\slc6a19b, Drer\zgc:158225, Drer\slc6a18, Drer\slc6a6a, Drer\slc6a17, Drer\slc6a4b, Drer\slc6a15, Drer\slc6a19a.1, Drer\slc6a1l, Drer\slc6a11a, Drer\slc6a6b, Drer\zgc:174946, Drer\slc6a8, Drer\slc6a13, Drer\slc6a2, Drer\si:ch211-132b12.2, Drer\slc6a9, Drer\si:ch211-117c9.5, Drer\slc6a13l, Drer\si:ch211-132b12.1, Drer\si:ch211-132b12.6, Drer\slc6a16a, Drer\slc6a13, Drer\slc6a4a, Drer\slc6a14, Drer\slc6a1a, Drer\si:ch211-132b12.3, Drer\slc6a1b" - "Cele\mod-5, Cele\snf-7, Cele\snf-11, Cele\snf-9, Cele\snf-3, Cele\snf-6, Cele\dat-1, Cele\snf-2, Cele\snf-5, Cele\snf-12, Cele\F56F4.3" "Xtro\slc6a17, Xtro\slc6a14.2, Xtro\slc6a2, Xtro\slc6a4, Xtro\slc6a8, Xtro\slc6a9, Xtro\slc6a7, Xtro\slc6a1, Xtro\slc6a13, Xtro\slc6a16, Xtro\slc6a15, Xtro\slc6a6, Xtro\slc6a5, Xtro\slc6a12, Xtro\slc6a3, Xtro\LOC100127682, Xtro\slc6a19" "Mmus\Slc6a20b, Mmus\Slc6a17, Mmus\Slc6a8, Mmus\Slc6a1, Mmus\Slc6a20a, Mmus\Slc6a7, Mmus\Slc6a6, Mmus\Slc6a19, Mmus\Slc6a15, Mmus\Slc6a3, Mmus\Slc6a4, Mmus\Slc6a11, Mmus\Slc6a12, Mmus\Slc6a13, Mmus\Slc6a18, Mmus\Slc6a9, Mmus\Slc6a5, Mmus\Slc6a2, Mmus\Slc6a14" "Hsap\SLC6A18, Hsap\SLC6A12, Hsap\SLC6A17, Hsap\SLC6A9, Hsap\SLC6A2, Hsap\SLC6A20, Hsap\SLC6A8, Hsap\SLC6A14, Hsap\SLC6A5, Hsap\SLC6A13, Hsap\SLC6A15, Hsap\SLC6A1, Hsap\SLC6A3, Hsap\SLC6A6, Hsap\SLC6A11, Hsap\SLC6A19, Hsap\SLC6A4" "viable,fertile,visual behavior defective" DRSC10424 E -0.215300238 -0.442615215 2.628437419 0.661281863 -0.245176889 -1.087931906 FBgn0027330 l(1)G0020 lethal (1) G0020 http://flybase.org/reports/FBgn0027330 FBgn0030062 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR033688 tRNA N-acetyltransferase activity ; GO:0051392 | inferred from biological aspect of ancestor with PANTHER:PTN002249848 tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN002249848 rRNA cytidine N-acetyltransferase activity ; GO:1990883 | inferred from biological aspect of ancestor with PANTHER:PTN000100786 neurogenesis ; GO:0022008 | inferred from mutant phenotype tRNA wobble cytosine modification ; GO:0002101 | inferred from biological aspect of ancestor with PANTHER:PTN002249848 rRNA acetylation involved in maturation of SSU-rRNA ; GO:1904812 | inferred from biological aspect of ancestor with PANTHER:PTN000100786 tRNA acetylation ; GO:0051391 | inferred from biological aspect of ancestor with PANTHER:PTN002249848 histone acetylation ; GO:0016573 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000100787 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000100787 "p110, CG1994, l(1)G0020, NAT10" "IPR013562:tRNA(Met) cytidine acetyltransferase TmcA, N-terminal, IPR032672:TmcA/NAT10/Kre33, IPR027992:Possible tRNA binding domain, IPR000182:GNAT domain, IPR007807:Helicase domain, IPR016181:Acyl-CoA N-acyltransferase, IPR033688:RNA cytidine acetyltransferase NAT10" CG1994 11-Aug-17 DroID_v2017_08 Drer\nat10 Scer\KRE33 Cele\nath-10 Xtro\nat10 Mmus\Nat10 Hsap\NAT10 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0031292 CG15824 - http://flybase.org/reports/FBgn0031292 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15824 IPR013783:Immunoglobulin-like fold CG15824 11-Aug-17 DroID_v2017_08 Drer\fbxo31 - - Xtro\fbxo31 Mmus\Fbxo31 Hsap\FBXO31 "viable,visible" trichogen cell FBgn0004065 Gsg71A Gastrula-specific transcript 71A http://flybase.org/reports/FBgn0004065 - gene - - - "gsg71A, Gsg71A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036972 CR6434 - http://flybase.org/reports/FBgn0036972 pseudogene_attribute - - - "CG6434, CR6434, mdcds_29715" - CR6434 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0263547 mir-4944 mir-4944 stem loop http://flybase.org/reports/FBgn0263547 miRNA_gene - - - "mir-4944, dme-mir-4944, CR43532" - CR43532 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262604 CR43130 - http://flybase.org/reports/FBgn0262604 non_protein_coding_gene - - - "CG43130, CR43130" - CR43130 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038748 CG12378 - http://flybase.org/reports/FBgn0038748 protein_coding_gene - - - CG12378 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013482 l(1)3P5 lethal (1) 3P5 http://flybase.org/reports/FBgn0013482 - gene - - - l(1)3P5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,rescuable maternal effect" FBgn0004047 Yp3 Yolk protein 3 http://flybase.org/reports/FBgn0004047 FBgn0000781 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 sex differentiation ; GO:0007548 | non-traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from expression pattern embryo development ; GO:0009790 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay extracellular region ; GO:0005576 | inferred from mutant phenotype P granule ; GO:0043186 | inferred from physical interaction with tud inferred from physical interaction with vas "Yp3, YP, yp3, yp, YP3, fs(1)1526, YP-3, YP[[3]], VG3, fs(1)A1526, CG11129, VIT3Dm, DIM 30, RH08557p" "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG11129 11-Aug-17 DroID_v2017_08 "Drer\lipca, Drer\lipia, Drer\pla1a, Drer\lipg, Drer\LOC101884800, Drer\lpl, Drer\LOC100331214, Drer\lipib" - - "Xtro\lpl, Xtro\lipg" "Mmus\Pnliprp1, Mmus\Lpl, Mmus\Lipc, Mmus\Liph, Mmus\Pnliprp2, Mmus\Pnlip, Mmus\Lipi, Mmus\Lipg, Mmus\Pla1a" "Hsap\LIPC, Hsap\LPL, Hsap\LIPG, Hsap\LIPI, Hsap\LIPH, Hsap\PNLIPRP3, Hsap\PNLIPRP2, Hsap\PNLIPRP1, Hsap\PNLIP, Hsap\PLA1A" "electrophoretic variant,lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0032851 CG13970 - http://flybase.org/reports/FBgn0032851 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "38B.19, CG13970" - CG13970 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038983 CG5326 - http://flybase.org/reports/FBgn0038983 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond neurogenesis ; GO:0022008 | inferred from mutant phenotype fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available CG5326 IPR002076:ELO family CG5326 11-Aug-17 DroID_v2017_08 "Drer\hsd17b8, Drer\zgc:101858, Drer\dhrs7, Drer\elovl4b, Drer\elovl8a, Drer\elovl7b, Drer\elovl8b, Drer\elovl5, Drer\elovl2, Drer\elovl1b, Drer\elovl7a, Drer\elovl4a, Drer\elovl1a" "Scer\ELO3, Scer\ELO1, Scer\ELO2" "Cele\F28H7.2, Cele\F25D1.5, Cele\Y47G6A.21, Cele\F26D2.15, Cele\ZK829.1, Cele\dhs-11, Cele\Y47G6A.22, Cele\dhs-14, Cele\C06E4.3, Cele\dhs-25" "Xtro\dhrs7, Xtro\MGC79752, Xtro\elovl2, Xtro\elovl1, Xtro\elovl5, Xtro\hsd17b8, Xtro\cbr4, Xtro\elovl7" "Mmus\Elovl5, Mmus\Elovl2, Mmus\Elovl1, Mmus\Cbr4, Mmus\H2-Ke6, Mmus\Elovl7, Mmus\Elovl4, Mmus\Dhrs7" "Hsap\ELOVL2, Hsap\HSD17B8, Hsap\CBR4, Hsap\DHRS7, Hsap\ELOVL1, Hsap\ELOVL5, Hsap\ELOVL4, Hsap\ELOVL7" "partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0001883 l(1)YQ09 lethal (1) YQ09 http://flybase.org/reports/FBgn0001883 - gene - - - l(1)YQ09 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051639 CG31639 - http://flybase.org/reports/FBgn0051639 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from electronic annotation with InterPro:IPR001578 molecular_function ; GO:0003674 | no biological data available ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR001578 protein deubiquitination ; GO:0016579 | inferred from electronic annotation with InterPro:IPR017390 biological_process ; GO:0008150 | no biological data available intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001578 cellular_component ; GO:0005575 | no biological data available "NEST:bs21c05, NEST:bs29d12, CG31639" "IPR001578:Peptidase C12, ubiquitin carboxyl-terminal hydrolase, IPR017390:Ubiquitinyl hydrolase, UCH37 type" CG31639 11-Aug-17 DroID_v2017_08 Drer\uchl5 - Cele\ubh-4 - Mmus\Uchl5 Hsap\UCHL5 viable FBgn0053771 CG33771 - http://flybase.org/reports/FBgn0053771 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14458, CG33771" IPR010512:Protein of unknown function DUF1091 CG33771 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005524 l(2)52ACa lethal (2) 52ACa http://flybase.org/reports/FBgn0005524 - gene - - - l(2)52ACa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050349 CG30349 - http://flybase.org/reports/FBgn0050349 protein_coding_gene - cellular response to starvation ; GO:0009267 | inferred from expression pattern - "CG2396, CG13750, CG30349" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR007148:Small-subunit processome, Utp12" CG30349 11-Aug-17 DroID_v2017_08 Drer\wdr43 Scer\UTP5 Cele\T10B5.3 Xtro\wdr43 Mmus\Wdr43 Hsap\WDR43 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039406 RpL34a Ribosomal protein L34a http://flybase.org/reports/FBgn0039406 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR008195 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000844532 structural constituent of ribosome ; GO:0003735 | traceable author statement myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR008195 translation ; GO:0006412 | inferred from sequence model ribosome biogenesis ; GO:0042254 | inferred from biological aspect of ancestor with PANTHER:PTN000844532 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR008195 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG6090, RpL34a, L34, RpL34" "IPR018065:Ribosomal protein L34e, conserved site, IPR008195:Ribosomal protein L34Ae" CG6090 11-Aug-17 DroID_v2017_08 Drer\rpl34 "Scer\RPL34B, Scer\RPL34A" Cele\rpl-34 Xtro\rpl34 "Mmus\Rpl34-ps1, Mmus\Rpl34, Mmus\Gm4705" Hsap\RPL34 lethal FBgn0036479 CG13458 - http://flybase.org/reports/FBgn0036479 protein_coding_gene - - - CG13458 "IPR002893:Zinc finger, MYND-type, IPR032717:Mitochondrial splicing suppressor 51, zinc-finger" CG13458 11-Aug-17 DroID_v2017_08 - - - - Mmus\Mss51 Hsap\MSS51 "viable,fertile" FBgn0046629 anon-38E.8 anon-38E.8 http://flybase.org/reports/FBgn0046629 gene - - - "38E.8, anon-38E.8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020052 E(w[a])829 E(w[a])829 http://flybase.org/reports/FBgn0020052 - gene - - - "E829, E(w[a])829" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,eye color defective" pigment cell FBgn0267123 CR45563 - http://flybase.org/reports/FBgn0267123 non_protein_coding_gene - - - CR45563 - CR45563 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001595 l(1)carot12 lethal (1) carot12 http://flybase.org/reports/FBgn0001595 - gene - - - l(1)carot12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032260 CG13144 - http://flybase.org/reports/FBgn0032260 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR001337 - viral capsid ; GO:0019028 | inferred from electronic annotation with InterPro:IPR001337 CG13144 "IPR001337:Tobacco mosaic virus-like, coat protein" CG13144 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" DRSC02241 K -0.811305917 -0.288616302 0.764629073 0.605461656 0.514386673 -2.522339945 FBgn0259788 anon-A24 - http://flybase.org/reports/FBgn0259788 gene - - - "anon-A24, DmA24" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065474 l(2)SH1314 lethal (2) SH1314 http://flybase.org/reports/FBgn0065474 gene - - - "l(2)SH1314, l(2)SH2 1314" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053372 5SrRNA:CR33372 5SrRNA:CR33372 http://flybase.org/reports/FBgn0053372 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33372, 5SrRNA:CR33372" - CR33372 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022936 CycH Cyclin H http://flybase.org/reports/FBgn0022936 - protein_coding_gene "cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | contributes_to inferred from direct assay cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | contributes_to inferred from direct assay transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of phosphorylation of RNA polymerase II C-terminal domain ; GO:1901409 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:1594 inferred from sequence or structural similarity with SGD:S000006229 "TFIIK complex ; GO:0070985 | inferred from electronic annotation with InterPro:IPR027081 holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:1594 inferred from sequence or structural similarity with SGD:S000006229 cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 holo TFIIH complex ; GO:0005675 | inferred from physical interaction with hay, Mat1, mrn, Xpd, Cdk7 carboxy-terminal domain protein kinase complex ; GO:0032806 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from direct assay" "142767_at, CG7405, CycH, CCNH" "IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like, IPR027081:CyclinH/Ccl1, IPR031658:Cyclin, C-terminal domain 2" CG7405 11-Aug-17 DroID_v2017_08 Drer\ccnh Scer\CCL1 Cele\cyh-1 Xtro\ccnh Mmus\Ccnh Hsap\CCNH "increased cell death,viable" spermatogonium FBgn0030778 CG4678 - http://flybase.org/reports/FBgn0030778 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000163972 peptide metabolic process ; GO:0006518 | inferred from biological aspect of ancestor with PANTHER:PTN000163972 protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000163972 cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000164185 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000163972 CG4678 "IPR000834:Peptidase M14, carboxypeptidase A, IPR008969:Carboxypeptidase-like, regulatory domain, IPR027062:Carboxypeptidase M" CG4678 11-Aug-17 DroID_v2017_08 "Drer\cpz, Drer\si:ch1073-459j12.1, Drer\cpdb, Drer\cpm, Drer\cpxm1b, Drer\cpda, Drer\cpe, Drer\cpn1, Drer\aebp1, Drer\cpxm1a" - "Cele\cpd-1, Cele\cpd-2, Cele\egl-21" "Xtro\cpn1, Xtro\cpz, Xtro\ebf4, Xtro\cpe, Xtro\cpxm2, Xtro\cpm" "Mmus\Cpe, Mmus\Cpxm1, Mmus\Cpz, Mmus\Aebp1, Mmus\Cpxm2, Mmus\Cpm, Mmus\Cpn1, Mmus\Cpd" "Hsap\CPZ, Hsap\CPM, Hsap\CPD, Hsap\CPXM1, Hsap\CPN1, Hsap\AEBP1, Hsap\CPE, Hsap\CPXM2" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" DRSC19911 K -0.151640671 0.10520871 0.551603192 0.155784418 1.55142103 0.568742998 FBgn0001955 l(2)28Ba lethal (2) 28Ba http://flybase.org/reports/FBgn0001955 - gene - - - "M, l(2)28Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051745 CG31745 - http://flybase.org/reports/FBgn0051745 protein_coding_gene - - - CG31745 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265728 CR44535 - http://flybase.org/reports/FBgn0265728 non_protein_coding_gene - - - "CR44535, incRNA.418, lincRNA.418" - CR44535 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261272 esi-2 endogenous siRNA 2 http://flybase.org/reports/FBgn0261272 gene - - - "esi-2, esiRNA-sl, hp-CG4068, hp-CG4068B, hp-CG4068G, CG4068B, esiRNA-sl-1, esi-2.1, esi-sl-1, esi-sl-4, esi-sl-4as, hpCG4068B, esl-2, esi CG4068-B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033855 link link http://flybase.org/reports/FBgn0033855 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype vesicle ; GO:0031982 | inferred from direct assay "link, CG13333" - CG13333 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC06368 IE 3.559409506 2.719408951 2.505935109 -1.426940535 -0.40172273 0.9166344 FBgn0028570 robl22E robl22E http://flybase.org/reports/FBgn0028570 protein_coding_gene "dynein intermediate chain binding ; GO:0045505 | inferred from sequence or structural similarity with robl dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with robl microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR016561 dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from sequence or structural similarity with robl dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG10838, robl22E, Robl22E" "IPR004942:Roadblock/LAMTOR2 domain, IPR016561:Dynein light chain roadblock-type 1/2" CG10838 11-Aug-17 DroID_v2017_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb1, Xtro\dynlrb2" "Mmus\Dynlrb1, Mmus\Dynlrb2" "Hsap\DYNLRB2, Hsap\DYNLRB1" viable FBgn0259714 DIP-epsilon Dpr-interacting protein epsilon http://flybase.org/reports/FBgn0259714 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG9511, CG9508, CG33295, CG13981, CG42368, 42368, DIP-epsilon" "IPR003598:Immunoglobulin subtype 2, IPR013098:Immunoglobulin I-set, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype" CG42368 11-Aug-17 DroID_v2017_08 "Drer\esama, Drer\igsf9bb, Drer\zgc:110372, Drer\si:ch1073-459j12.1, Drer\esamb, Drer\lrit1b, Drer\kirrelb, Drer\jam3a, Drer\vsig8a, Drer\lrit1a, Drer\jam2b, Drer\LOC100151468, Drer\cxadr, Drer\ncam1b, Drer\kirrel3l, Drer\lsamp, Drer\si:dkey-250k15.10, Drer\itgb4, Drer\si:ch211-215e19.3, Drer\sdk1b, Drer\sdk1a, Drer\ntm, Drer\si:dkey-65b12.12, Drer\si:zfos-1011f11.1, Drer\paplna, Drer\lrit3b, Drer\si:ch211-9d9.7, Drer\jam2a, Drer\ush2a, Drer\zgc:153073, Drer\opcml, Drer\cxcr3.1, Drer\lrit3a, Drer\gpa33, Drer\mxra8a, Drer\f11r.2, Drer\f11r.1, Drer\pigrl4.2, Drer\negr1, Drer\kirrel3b, Drer\dscama, Drer\vsig8b, Drer\igsf11, Drer\kirrela, Drer\kirrel3a, Drer\igsf9a, Drer\jam3b, Drer\mxra8b" - "Cele\zig-7, Cele\rig-5, Cele\zig-1, Cele\zig-11" "Xtro\kirrel2, Xtro\ntm, Xtro\igsf9b, Xtro\negr1, Xtro\papln, Xtro\lsamp, Xtro\lrit3" "Mmus\Hepacam2, Mmus\Kirrel3, Mmus\Cxadr, Mmus\Ntm, Mmus\Lsamp, Mmus\Esam, Mmus\Vsig1, Mmus\Kirrel2, Mmus\Mxra8, Mmus\F11r, Mmus\Jam3, Mmus\Vsir, Mmus\Igsf9b, Mmus\Vsig8, Mmus\Papln, Mmus\Lrit3, Mmus\Jam2, Mmus\Negr1, Mmus\Clmp, Mmus\Opcml, Mmus\Igsf5, Mmus\Iglon5, Mmus\Igsf11, Mmus\Vsig2, Mmus\Kirrel, Mmus\Gpa33, Mmus\Gm1123, Mmus\Ptprq, Mmus\Lrit1, Mmus\Sdk1" "Hsap\CLMP, Hsap\SDK1, Hsap\ESAM, Hsap\VSIG1, Hsap\OPCML, Hsap\CXADR, Hsap\NTM, Hsap\JAM3, Hsap\C10orf54, Hsap\KIRREL, Hsap\LRIT3, Hsap\KIRREL2, Hsap\IGLON5, Hsap\F11R, Hsap\IGSF9B, Hsap\IGSF11, Hsap\VSIG8, Hsap\NEGR1, Hsap\PAPLN, Hsap\VSIG2, Hsap\C1orf204, Hsap\JAM2, Hsap\GPA33, Hsap\LRIT1, Hsap\KIRREL3, Hsap\LSAMP, Hsap\USH2A, Hsap\MXRA8, Hsap\IGSF5" "viable,visible" mesothoracic tergum """DRSC02313, DRSC00932, DRSC29110"" " IEK FBgn0036679 CG13022 - http://flybase.org/reports/FBgn0036679 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13022 - CG13022 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069449 E(br)187 E(br)187 http://flybase.org/reports/FBgn0069449 gene - - - E(br)187 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262810 CG43181 - http://flybase.org/reports/FBgn0262810 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43181, chrX_244575_245164.0" - CG43181 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032633 Lrch Leucine-rich-repeats and calponin homology domain protein http://flybase.org/reports/FBgn0032633 protein_coding_gene - signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN002351852 cell cortex ; GO:0005938 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay "CT21229, Lrch, CG6860, dLRCH" "IPR000595:Cyclic nucleotide-binding domain, IPR001611:Leucine-rich repeat, IPR001715:Calponin homology domain, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG6860 11-Aug-17 DroID_v2017_08 "Drer\lrch3, Drer\lrch4, Drer\lrch2, Drer\lrrc18b, Drer\lrrc18a, Drer\mfhas1, Drer\lrch1" - "Cele\lrch-1, Cele\F56A8.3" "Xtro\lrch3, Xtro\lrch1, Xtro\lrsam1, Xtro\lrch2" "Mmus\Mfhas1, Mmus\Lrch2, Mmus\Lrch1, Mmus\Lrch3, Mmus\Lrrc18, Mmus\Lrch4, Mmus\Erbin" "Hsap\LRCH3, Hsap\ERBIN, Hsap\LRCH2, Hsap\MFHAS1, Hsap\LRRC18, Hsap\LRCH4, Hsap\LRCH1" viable FBgn0037222 CG14642 - http://flybase.org/reports/FBgn0037222 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP29, CG14642" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG14642 11-Aug-17 DroID_v2017_08 - - "Cele\try-3, Cele\svh-1" - - - viable FBgn0053414 5SrRNA:CR33414 5SrRNA:CR33414 http://flybase.org/reports/FBgn0053414 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33414, 5SrRNA:CR33414" - CR33414 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004534 l(4)102ABf lethal (4) 102ABf http://flybase.org/reports/FBgn0004534 - gene - - - "l(4)20, l(4)102ABf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0004687 Mlc-c Myosin light chain cytoplasmic http://flybase.org/reports/FBgn0004687 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 protein binding ; GO:0005515 | inferred from physical interaction with asp myosin heavy chain binding ; GO:0032036 | inferred from physical interaction with didum myosin binding ; GO:0017022 | inferred from physical interaction with didum myosin heavy chain binding ; GO:0032036 | inferred from physical interaction with ck inferred from physical interaction with jar inferred from physical interaction with zip actin filament-based movement ; GO:0030048 | inferred by curator from GO:0016460 actin filament-based movement ; GO:0030048 | inferred from direct assay myosin V complex ; GO:0031475 | inferred from physical interaction with didum myosin II complex ; GO:0016460 | inferred from physical interaction with zip myosin VII complex ; GO:0031477 | inferred from physical interaction with ck myosin VI complex ; GO:0031476 | inferred from physical interaction with jar myosin complex ; GO:0016459 | inferred from sequence or structural similarity "nmELC, DmMLC_C, CG3201, Mlc-c, mlc-c, MyoII, ELC1, ELC" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG3201 11-Aug-17 DroID_v2017_08 "Drer\zgc:153867, Drer\mylz3, Drer\zgc:163073, Drer\myl1, Drer\myl13, Drer\myl6, Drer\cmlc1, Drer\myl4" Scer\MLC1 "Cele\mlc-5, Cele\mlc-7, Cele\cal-7, Cele\mlc-6" "Xtro\myl6, Xtro\myl4, Xtro\myl3, Xtro\myl1" "Mmus\Myl6, Mmus\Myl6b, Mmus\Myl1, Mmus\Myl4, Mmus\Myl3" "Hsap\MYL6, Hsap\MYL6B, Hsap\MYL1, Hsap\MYL4, Hsap\MYL3" viable FBgn0001117 gn glisten http://flybase.org/reports/FBgn0001117 - gene - - - gn - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,ommatidium,interommatidial bristle" FBgn0265067 CR44178 - http://flybase.org/reports/FBgn0265067 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44178, CR44178" - CR44178 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031623 Taf12L TBP-associated factor 30kD subunit alpha-2 http://flybase.org/reports/FBgn0031623 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with nht RNA polymerase II activating transcription factor binding ; GO:0001102 | inferred from biological aspect of ancestor with PANTHER:PTN000262707 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000262707 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000262707 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000262707 RNA polymerase II transcriptional preinitiation complex assembly ; GO:0051123 | inferred from biological aspect of ancestor with PANTHER:PTN000262707 histone H3 acetylation ; GO:0043966 | inferred from biological aspect of ancestor with PANTHER:PTN000262707 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11545 inferred from sequence or structural similarity with SGD:S000002552 male germ cell nucleus ; GO:0001673 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11545 inferred from sequence or structural similarity with SGD:S000002552 SAGA complex ; GO:0000124 | inferred from biological aspect of ancestor with PANTHER:PTN000262707 transcription factor TFIID complex ; GO:0005669 | inferred from biological aspect of ancestor with PANTHER:PTN000262707 "dTAF12L, rye, dTAF12, TAF, TFIID, dTAF[[II]]30a, dmTAF12b, dTAF[[II]]30alpha-2, TAF[[II]], dmTAF12L, CG15632, Taf30alpha-2, TAF30alpha-2, Taf12L, TAF12L, Rye" "IPR003228:Transcription initiation factor TFIID, subunit 12, IPR009072:Histone-fold" CG15632 11-Aug-17 DroID_v2017_08 Drer\taf12 Scer\TAF12 Cele\taf-12 Xtro\taf12 Mmus\Taf12 Hsap\TAF12 FBgn0032276 CG17098 - http://flybase.org/reports/FBgn0032276 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN001128910 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17098 "IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013087:Zinc finger C2H2-type" CG17098 11-Aug-17 DroID_v2017_08 "Drer\zmat4b, Drer\znf385a, Drer\znf385b, Drer\zgc:171482, Drer\zmat4a, Drer\zmat3, Drer\znf385c, Drer\zgc:114104, Drer\znf346" - - "Xtro\znf385a, Xtro\znf385b, Xtro\znf385c, Xtro\krcc1" "Mmus\Zmat1, Mmus\Zmat3, Mmus\Krcc1, Mmus\Zfp385c, Mmus\Zfp346, Mmus\Zfp385b, Mmus\Zmat4, Mmus\Zfp385a" "Hsap\ZNF385B, Hsap\ZNF385D, Hsap\ZNF385A, Hsap\ZMAT3, Hsap\ZMAT4, Hsap\KRCC1, Hsap\ZNF346, Hsap\ZNF385C, Hsap\ZMAT1" DRSC02570 K -0.776278929 0.104380633 0.143300691 0.649355764 1.628176788 0.590614665 FBgn0264386 Ca-alpha1T Ca[2+]-channel protein alpha[[1]] subunit T http://flybase.org/reports/FBgn0264386 protein_coding_gene low voltage-gated calcium channel activity ; GO:0008332 | inferred from mutant phenotype voltage-gated sodium channel activity ; GO:0005248 | inferred from biological aspect of ancestor with PANTHER:PTN000798901 neuronal action potential ; GO:0019228 | inferred from biological aspect of ancestor with PANTHER:PTN000798901 membrane depolarization during action potential ; GO:0086010 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 calcium ion transmembrane transport ; GO:0070588 | inferred from mutant phenotype voltage-gated calcium channel complex ; GO:0005891 | inferred from electronic annotation with InterPro:IPR005445 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 "Ca-alpha1T, DmalphaG, CG15899, Caalpha1T, CG4222, CG12544, Dmca1G, Ca1G, Ca-alphaT-RC, cat, alpha1T" "IPR005445:Voltage-dependent calcium channel, T-type, alpha-1 subunit, IPR005821:Ion transport domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG15899 11-Aug-17 DroID_v2017_08 "Drer\cacna1g, Drer\cacna1hb, Drer\cacna1i, Drer\cacna1ha" Scer\CCH1 Cele\cca-1 "Xtro\cacna1h, Xtro\cacna1i, Xtro\cacna1g" "Mmus\Cacna1i, Mmus\Cacna1g, Mmus\Cacna1h" "Hsap\CACNA1G, Hsap\CATSPER1, Hsap\CACNA1I, Hsap\CACNA1H" DRSC17842 K 0.080944759 -0.370035843 -0.064673309 -0.315747088 -1.76304499 -0.56085166 FBgn0039712 CG15514 - http://flybase.org/reports/FBgn0039712 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 - - "CG15514, CC30" "IPR003656:Zinc finger, BED-type, IPR013087:Zinc finger C2H2-type" CG15514 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264669 wavy-lumens wavy lumens http://flybase.org/reports/FBgn0264669 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - wavy-lumens - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0040699 CG15024 - http://flybase.org/reports/FBgn0040699 protein_coding_gene - - - CG15024 - CG15024 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085405 CG34376 - http://flybase.org/reports/FBgn0085405 protein_coding_gene - regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 "CG34376, CG13845, CG31160, CG13851, CG13846" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR007588:Zinc finger, FLYWCH-type" CG34376 11-Aug-17 DroID_v2017_08 - - - - - "Hsap\NACC1, Hsap\NACC2, Hsap\ZBTB9" FBgn0267963 CR46243 - http://flybase.org/reports/FBgn0267963 non_protein_coding_gene - - - "CR46243, lincRNA.940" - CR46243 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038195 CG3061 - http://flybase.org/reports/FBgn0038195 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay CG3061 "IPR001623:DnaJ domain, IPR015399:Domain of unknown function DUF1977, DnaJ-like" CG3061 11-Aug-17 DroID_v2017_08 "Drer\dnajb1b, Drer\dnajb12a, Drer\dnajc22, Drer\dnajc18, Drer\dnajc4, Drer\dnajb9a, Drer\dnajc7, Drer\dnajb12b, Drer\dnajb14, Drer\dnajb1a, Drer\dnajb5, Drer\dnajb4, Drer\dnajb2" "Scer\DJP1, Scer\XDJ1, Scer\HLJ1, Scer\SIS1, Scer\MDJ1" "Cele\dnj-18, Cele\dnj-16, Cele\dnj-17, Cele\dnj-1, Cele\dnj-26" "Xtro\dnajb14, Xtro\dnajb6, Xtro\dnajb1, Xtro\dnajb5, Xtro\dnajb13, Xtro\dnajb4, Xtro\dnajc18, Xtro\dnajb12, Xtro\dnajb9, Xtro\dnajb2, Xtro\dnajc22" "Mmus\Dnajb1, Mmus\Dnajb12, Mmus\Dnajc4, Mmus\Dnajb4, Mmus\Dnajb9, Mmus\Dnajb6, Mmus\Dnajb2, Mmus\4930503B20Rik, Mmus\Dnajc18, Mmus\Dnajb14, Mmus\Dnajc21, Mmus\Dnajb3, Mmus\Dnajc7, Mmus\Dnajb13, Mmus\Dnajb8, Mmus\Dnajb5, Mmus\Dnajb7, Mmus\Dnajc22" "Hsap\DNAJB12, Hsap\DNAJC18, Hsap\DNAJB8, Hsap\DNAJC7, Hsap\DNAJB7, Hsap\DNAJB13, Hsap\DNAJB6, Hsap\DNAJB1, Hsap\DNAJB5, Hsap\DNAJC22, Hsap\DNAJB9, Hsap\DNAJB2, Hsap\DNAJB4, Hsap\DNAJB14, Hsap\DNAJC4" viable FBgn0085367 CG34338 - http://flybase.org/reports/FBgn0085367 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34338 - CG34338 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045033 ultB ultrahair B http://flybase.org/reports/FBgn0045033 gene - - - "uhr, ultB" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051974 CG31974 - http://flybase.org/reports/FBgn0051974 protein_coding_gene - - - "CG18501, CG31974" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG31974 11-Aug-17 DroID_v2017_08 - - "Cele\H06H21.8, Cele\F59B1.10, Cele\dhs-27, Cele\C29F7.1, Cele\C29F7.2, Cele\F59B1.8, Cele\nhr-246" - - - viable FBgn0082944 snoRNA:Me28S-A2634c snoRNA:Me28S-A2634c http://flybase.org/reports/FBgn0082944 snoRNA_gene - - - "snoRNA:Me28S-A2634c, Me28S-Am2634c, CR34634, Me28S-A2634c" - CR34634 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011561 adm all discs missing http://flybase.org/reports/FBgn0011561 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc growth ; GO:0007446 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available adm - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036334 CG11267 - http://flybase.org/reports/FBgn0036334 protein_coding_gene metal ion binding ; GO:0046872 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 response to unfolded protein ; GO:0006986 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 chaperone mediated protein folding requiring cofactor ; GO:0051085 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000080669 mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "anon-WO0118547.175, CG11267, Hsp10" "IPR011032:GroES-like, IPR020818:GroES chaperonin family" CG11267 11-Aug-17 DroID_v2017_08 Drer\hspe1 Scer\HSP10 Cele\Y22D7AL.10 Xtro\hspe1 Mmus\Hspe1 Hsap\HSPE1 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0035581 Dnah3 "dynein, axonemal, heavy chain 3" http://flybase.org/reports/FBgn0035581 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" sperm competition ; GO:0046692 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 response to auditory stimulus ; GO:0010996 | inferred from mutant phenotype dynein complex ; GO:0030286 | inferred from sequence or structural similarity inner dynein arm ; GO:0036156 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 "CG17150, DHC7B, DHC64C, Dnah3" "IPR004273:Dynein heavy chain domain, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain" CG17150 11-Aug-17 DroID_v2017_08 "Drer\dync1h1, Drer\wu:fj30b09, Drer\dnah1, Drer\si:dkeyp-86b9.1, Drer\dnah7, Drer\dnah12, Drer\dnah7l, Drer\dnah2, Drer\dnah3, Drer\dnah9l, Drer\si:dkeyp-87a6.1" Scer\DYN1 "Cele\che-3, Cele\dhc-1" "Xtro\dnah14, Xtro\dnah2, Xtro\dnah7, Xtro\dnah3" "Mmus\Dnah2, Mmus\Dnah17, Mmus\Dnhd1, Mmus\Dnah10, Mmus\Dnah7a, Mmus\Dnah11, Mmus\Dnah12, Mmus\Dnah7c, Mmus\Dnah1, Mmus\Dnah5, Mmus\Dnah9, Mmus\Dnah3, Mmus\Dnah8, Mmus\Dnah6, Mmus\Dnah7b, Mmus\Dync2h1, Mmus\Dync1h1" "Hsap\DNAH1, Hsap\DNAH10, Hsap\DNAH12, Hsap\DNAH17, Hsap\DNHD1, Hsap\DYNC1H1, Hsap\DYNC2H1, Hsap\DNAH7, Hsap\DNAH9, Hsap\DNAH3, Hsap\CCDC88B, Hsap\DNAH11, Hsap\DNAH14, Hsap\DNAH8, Hsap\DNAH2, Hsap\DNAH6, Hsap\DNAH5" "viable,fertile" FBgn0014908 anon-4Fb anon-4Fb http://flybase.org/reports/FBgn0014908 - gene - - - anon-4Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041098 quiescin quiescin http://flybase.org/reports/FBgn0041098 gene - - - "PDI(II), quiescin" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020546 iab-4 iab-4 http://flybase.org/reports/FBgn0020546 "FBan0031271, FBgn0051271" non_protein_coding_gene - - - "iab, I, CR31271, iab-4, pri-mir-iab-4_mir-iab-4as" - CR31271 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 1-17 , embryonic stage | stage stage 8 , embryonic stage | stage 4 , embryonic stage | stage 8 " " parasegment 8-14 &&of embryonic ventral nervous system

,

posterior , parasegment 8--14

,

10-60% egg length " "viable,visible,homeotic,male sterile,female sterile,recessive" "adult abdominal segment 2,adult abdominal segment 5,adult abdominal segment 4,gonad,precursor,pole cell,adult abdominal segment 1,ovary,oviduct,testis" FBgn0039532 Mtl Mig-2-like http://flybase.org/reports/FBgn0039532 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with WB:WBGene00003239" "lamellipodium assembly ; GO:0030032 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | traceable author statement JNK cascade ; GO:0007254 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from genetic interaction with Rac1, Rac2 hemocyte migration ; GO:0035099 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype positive regulation of wound healing ; GO:0090303 | inferred from genetic interaction with Rac1, Rac2 establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement Rho protein signal transduction ; GO:0007266 | inferred from sequence or structural similarity with HGNC:672 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype dorsal closure, elongation of leading edge cells ; GO:0007394 | inferred from mutant phenotype" intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003578 cellular_component ; GO:0005575 | no biological data available "Rac GTPase, mtl, dMig-2, Mt1/Mig2-like, CG5588, Mtl, Rac, Rac-like, MTL, 5588, Mig-2-like" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003578:Small GTPase superfamily, Rho type" CG5588 11-Aug-17 DroID_v2017_08 "Drer\rnd3a, Drer\rnd3b, Drer\rhov, Drer\rac1a, Drer\rnd1a, Drer\cdc42l, Drer\cdc42l2, Drer\rhoj, Drer\rhoga, Drer\si:dkey-6b12.5, Drer\rhobtb2a, Drer\cdc42, Drer\si:dkey-263f15.2, Drer\LOC100331257, Drer\rhoac, Drer\rnd1b, Drer\LOC100537765, Drer\rhogc, Drer\rac3a, Drer\rhof, Drer\rnd2, Drer\rhogb, Drer\rhobtb1, Drer\rhoua, Drer\rhoh, Drer\rac1l, Drer\rhobtb2b, Drer\rhogd, Drer\rhoub, Drer\rhoab, Drer\rhocb, Drer\rac3b, Drer\si:ch211-133l11.10, Drer\rhoca, Drer\rhoq, Drer\rac1b, Drer\rhoaa, Drer\rac2" "Scer\RHO2, Scer\RHO1, Scer\RHO5, Scer\RHO4, Scer\CDC42, Scer\RHO3" "Cele\cdc-42, Cele\rac-2, Cele\mig-2, Cele\ced-10" "Xtro\rhoa, Xtro\rhov, Xtro\rnd1, Xtro\rhob, Xtro\rac2, Xtro\cdc42, Xtro\rhobtb2, Xtro\rhobtb3, Xtro\rhoc, Xtro\rnd3, Xtro\rhou, Xtro\rhoj, Xtro\rhobtb1, Xtro\rac1, Xtro\rhof, Xtro\rhoa.2" "Mmus\Rhobtb3, Mmus\Rhoc, Mmus\Rac3, Mmus\Rhof, Mmus\Rhoh, Mmus\Rac1, Mmus\Cdc42, Mmus\Rnd1, Mmus\Rac2, Mmus\Rhou, Mmus\Rhobtb1, Mmus\Rhod, Mmus\Rhoj, Mmus\Rhoa, Mmus\Rnd2, Mmus\Rhov, Mmus\Rhog, Mmus\Rhob, Mmus\4930544G11Rik, Mmus\Rnd3, Mmus\Rhobtb2, Mmus\Rhoq" "Hsap\RHOF, Hsap\RHOH, Hsap\RHOA, Hsap\RND3, Hsap\RHOG, Hsap\RHOB, Hsap\RHOD, Hsap\RHOJ, Hsap\RHOQ, Hsap\RND1, Hsap\RHOV, Hsap\RND2, Hsap\RHOC, Hsap\RAC2, Hsap\RAC3, Hsap\RHOU, Hsap\RHOBTB3, Hsap\CDC42, Hsap\RAC1, Hsap\RHOBTB1, Hsap\RHOBTB2" "viable,fertile,planar polarity defective,wild-type,cell shape defective" "eye,ommatidium,wing hair,supernumerary,longitudinal connective,adult mushroom body,presumptive embryonic salivary gland" FBgn0267661 CR45999 - http://flybase.org/reports/FBgn0267661 non_protein_coding_gene - - - CR45999 - CR45999 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051130 tRNA:Leu-TAA-4-1 transfer RNA:Leucine-TAA 4-1 http://flybase.org/reports/FBgn0051130 tRNA_gene UUA codon-amino acid adaptor activity ; GO:0033403 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033403 cytosol ; GO:0005829 | inferred by curator from GO:0033403 "AE002708.trna29-LeuTAA, tRNA:L:TAA:AE002708-b, CR31130, chr3R.trna35-LeuTAA, tRNA-Leu-TAA-4-1, tRNA:Leu-TAA-4-1, tRNA:CR31130, UUA" - CR31130 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038257 smp-30 Senescence marker protein-30 http://flybase.org/reports/FBgn0038257 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with HGNC:9989 negative regulation of imaginal disc-derived wing size ; GO:0044720 | inferred from mutant phenotype cold acclimation ; GO:0009631 | inferred from expression pattern regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis ; GO:0090256 | inferred from mutant phenotype cold acclimation ; GO:0009631 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from sequence model "Smp-30, CT22723, Dca, CG7390, smp-30" "IPR011042:Six-bladed beta-propeller, TolB-like, IPR005511:Senescence marker protein-30 (SMP-30), IPR013658:SMP-30/Gluconolactonase/LRE-like region" CG7390 11-Aug-17 DroID_v2017_08 Drer\rgn Scer\YBR053C - Xtro\rgn Mmus\Rgn Hsap\RGN "size defective,viable" wing FBgn0062618 Mod(var)1205 Mod(var)1205 http://flybase.org/reports/FBgn0062618 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1205, Mod(var)1205" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced,suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0069453 E(br)121 E(br)121 http://flybase.org/reports/FBgn0069453 gene - - - E(br)121 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semidominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" leg FBgn0058195 CG40195 - http://flybase.org/reports/FBgn0058195 protein_coding_gene - - - CG40195 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259219 CG42319 - http://flybase.org/reports/FBgn0259219 protein_coding_gene - - - "CG42319, CG17041, CG17042" IPR001478:PDZ domain CG42319 11-Aug-17 DroID_v2017_08 "Drer\ldb3b, Drer\pdlim7, Drer\ldb3a, Drer\LOC103910026, Drer\pdlim5a, Drer\pdlim5b, Drer\pdlim2" - "Cele\alp-1, Cele\ZK1321.4" Xtro\pdlim7 "Mmus\Pdlim7, Mmus\Pdlim5, Mmus\Ldb3, Mmus\Pdlim2" "Hsap\PDLIM7, Hsap\LDB3, Hsap\PDLIM2, Hsap\PDLIM5" FBgn0263608 l(3)72Dr lethal (3) 72Dr http://flybase.org/reports/FBgn0263608 protein_coding_gene omega peptidase activity ; GO:0008242 | inferred from electronic annotation with InterPro:IPR015527 "glutamine metabolic process ; GO:0006541 | inferred from electronic annotation with InterPro:IPR011697, InterPro:IPR015527 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available "CG32154, l(3)72Dr, CG5082" "IPR011697:Peptidase C26, IPR015527:Peptidase C26, gamma-glutamyl hydrolase, IPR029062:Class I glutamine amidotransferase-like" CG32154 11-Aug-17 DroID_v2017_08 "Drer\zgc:171566, Drer\ggh, Drer\LOC553228" - - Xtro\ggh Mmus\Ggh Hsap\GGH FBgn0011185 l(1)294-31 lethal (1) 294-31 http://flybase.org/reports/FBgn0011185 FBgn0010200 gene - - - "294-31, l(1)294-31" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025514 fs(3)82EFb fs(3)82EFb http://flybase.org/reports/FBgn0025514 - gene - - - fs(3)82EFb - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0030026 sni sniffer http://flybase.org/reports/FBgn0030026 protein_coding_gene carbonyl reductase (NADPH) activity ; GO:0004090 | inferred from direct assay oxidation-reduction process ; GO:0055114 | inferred from direct assay - "CG10964, anon-WO03040301.183, sni, SNI, Sni" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG10964 11-Aug-17 DroID_v2017_08 "Drer\zgc:65997, Drer\zgc:158868, Drer\zgc:92161, Drer\zgc:110339, Drer\si:dkey-12e7.4, Drer\zgc:112146, Drer\zgc:163083, Drer\si:ch73-186j5.2, Drer\zgc:123284" "Scer\TDA5, Scer\YKL071W" "Cele\C30G12.2, Cele\ZK697.14, Cele\C55A6.3, Cele\sdz-8, Cele\C55A6.6, Cele\dhs-31, Cele\F20G2.1, Cele\C55A6.7, Cele\dhs-12, Cele\C55A6.4, Cele\F20G2.2" Xtro\MGC147117 "Mmus\Rdh5, Mmus\Hsd17b2" Hsap\RDH5 "viable,short lived,neuroanatomy defective,increased cell death,chemical sensitive,gravitaxis defective,locomotor behavior defective,long lived,conditional,chemical resistant" "lamina monopolar neuron,lamina & glial cell" FBgn0051461 CG31461 - http://flybase.org/reports/FBgn0051461 protein_coding_gene - - - CG31461 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032214 CG4968 - http://flybase.org/reports/FBgn0032214 protein_coding_gene NEDD8-specific protease activity ; GO:0019784 | inferred from biological aspect of ancestor with PANTHER:PTN000309332 ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000309332 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from biological aspect of ancestor with PANTHER:PTN000309332 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:23077 protein K48-linked deubiquitination ; GO:0071108 | inferred from sequence or structural similarity with HGNC:23077 protein K48-linked deubiquitination ; GO:0071108 | inferred from biological aspect of ancestor with PANTHER:PTN000309332 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000309332 "CG4968, Q9VL00, OTUB1" "IPR003323:OTU domain, IPR016615:Ubiquitin thioesterase Otubain, IPR019400:Peptidase C65, otubain, IPR030298:Ubiquitin thioesterase OTUB1" CG4968 11-Aug-17 DroID_v2017_08 "Drer\otub1b, Drer\otub1a" - Cele\otub-1 Xtro\otub2 "Mmus\Otub2, Mmus\Otub1" "Hsap\OTUB2, Hsap\OTUB1" viable FBgn0037918 CG6791 - http://flybase.org/reports/FBgn0037918 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG6791 IPR013087:Zinc finger C2H2-type CG6791 11-Aug-17 DroID_v2017_08 "Drer\LOC568955, Drer\gtf3aa, Drer\znf1010" Scer\PZF1 "Cele\F21A9.2, Cele\pqm-1, Cele\F10B5.3" - "Mmus\Gtf3a, Mmus\Zfp444" "Hsap\ZNF444, Hsap\GTF3A" "partially lethal - majority die,some die during pupal stage" FBgn0061107 l(3)S007915 lethal (3) S007915 http://flybase.org/reports/FBgn0061107 gene - - - "0079/15, l(3)S007915" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262572 CG43112 - http://flybase.org/reports/FBgn0262572 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43112, MIP12787" - CG43112 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025176 l(1)TW24 lethal (1) TW24 http://flybase.org/reports/FBgn0025176 - gene - - - l(1)TW24 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262951 CR43270 - http://flybase.org/reports/FBgn0262951 non_protein_coding_gene - - - "CR43270, pri-mir-958" - CR43270 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034084 CG8435 - http://flybase.org/reports/FBgn0034084 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG8435 IPR007590:CWC16 protein CG8435 11-Aug-17 DroID_v2017_08 "Drer\ccdc130, Drer\ccdc94" Scer\YJU2 "Cele\ZK1307.9, Cele\F37C12.1" Xtro\ccdc94 "Mmus\Ccdc130, Mmus\Ccdc94" "Hsap\CCDC130, Hsap\CCDC94" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC07179 E 0.985389042 1.381681456 0.232652494 1.652620704 0.17262788 -0.091062901 FBgn0264365 CR43817 - http://flybase.org/reports/FBgn0264365 non_protein_coding_gene - - - CR43817 - CR43817 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005193 l(2)S59 lethal of Seto 59 http://flybase.org/reports/FBgn0005193 - gene - - - l(2)S59 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "wing,leg" FBgn0001423 l(1)6Dg lethal (1) 6Dg http://flybase.org/reports/FBgn0001423 - gene - - - l(1)6Dg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,maternal effect" "egg,germline clone,maternal effect,female reproductive system,ovariole" FBgn0001514 l(1)10Fh lethal (1) 10Fh http://flybase.org/reports/FBgn0001514 - gene - - - l(1)10Fh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040508 ACXC ACXC http://flybase.org/reports/FBgn0040508 protein_coding_gene guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 adenylate cyclase activity ; GO:0004016 | inferred from sequence model adenylate cyclase activity ; GO:0004016 | non-traceable author statement intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054 spermatogenesis ; GO:0007283 | inferred from expression pattern cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 "integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG5983, AC, DACXC, ACXC, Acxc" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR029787:Nucleotide cyclase" CG5983 11-Aug-17 DroID_v2017_08 "Drer\adcy3a, Drer\adcy2a, Drer\adcy1b, Drer\adcy7, Drer\adcy6a, Drer\adcy5, Drer\si:ch211-132f19.7, Drer\adcy1a, Drer\adcy8, Drer\adcy6b, Drer\si:dkey-206f10.1, Drer\adcy2b" - "Cele\acy-2, Cele\acy-4" "Xtro\adcy1, Xtro\adcy6, Xtro\adcy4, Xtro\dnajc27, Xtro\adcy7" "Mmus\Adcy3, Mmus\Adcy8, Mmus\Adcy5, Mmus\Adcy4, Mmus\Adcy2, Mmus\Adcy1, Mmus\Adcy7, Mmus\Adcy6" "Hsap\ADCY2, Hsap\ADCY7, Hsap\ADCY4, Hsap\ADCY5, Hsap\ADCY3, Hsap\ADCY8, Hsap\ADCY1, Hsap\ADCY6" " adult stage | male && spermatogenesis , larval stage | late , pupal stage , adult stage | male " " spermatocyte

, spermatid

" viable FBgn0262408 mir-5 mir-5 stem loop http://flybase.org/reports/FBgn0262408 miRNA_gene - - - "mir-5, 5, miR-5, CR42952, CR33036, dme-miR-5, dme-mir-5" - CR42952 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , larval stage | first instar " "viable,visible" 1st posterior cell FBgn0262856 CG43220 - http://flybase.org/reports/FBgn0262856 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43220, DMG8-chr2L.31.003" - CG43220 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263321 CG43402 - http://flybase.org/reports/FBgn0263321 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43402 - CG43402 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013559 l(3)ry59 lethal (3) ry59 http://flybase.org/reports/FBgn0013559 - gene - - - "l(3)59, l(3)ry59" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005139 l(2)1542 lethal (2) 1542 http://flybase.org/reports/FBgn0005139 - gene - - - l(2)1542 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,tumorigenic" "ganglion mother cell,imaginal disc,neuroblast" FBgn0065618 l(2)SH0810 lethal (2) SH0810 http://flybase.org/reports/FBgn0065618 gene - - - "l(2)SH0810, l(2)SH2 0810" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038214 CG9616 - http://flybase.org/reports/FBgn0038214 protein_coding_gene - - - CG9616 "IPR031986:Serine protease gd, N-terminal domain" CG9616 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037290 CG1124 - http://flybase.org/reports/FBgn0037290 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CT1789, CG1124" IPR010562:Haemolymph juvenile hormone binding CG1124 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037855 CG6621 - http://flybase.org/reports/FBgn0037855 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - "CG6621, TTC14" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG6621 11-Aug-17 DroID_v2017_08 Drer\ttc14 - - Xtro\ttc14 Mmus\Ttc14 Hsap\TTC14 viable FBgn0003417 Splotched Splotched http://flybase.org/reports/FBgn0003417 - gene - - - "Splotched, Sl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable,good,male" wing hair FBgn0082194 aos::spi::vn argos::spi::vn http://flybase.org/reports/FBgn0082194 engineered_fusion_gene - - - "argos::spi::vn, aos::spi::vn" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible anterior crossvein FBgn0039167 CG17786 - http://flybase.org/reports/FBgn0039167 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17786 - CG17786 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" tormogen cell DRSC15270 E -0.042932761 -0.05074378 -1.618146893 -0.534345131 0.084292027 0.02986792 FBgn0019787 l(1)16 lethal (1) 16 http://flybase.org/reports/FBgn0019787 - gene - - - l(1)16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003864 telescope telescope http://flybase.org/reports/FBgn0003864 - gene - - - "telescope, ts" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,adult abdominal segment" FBgn0034549 CG18413 - http://flybase.org/reports/FBgn0034549 protein_coding_gene - - - CG18413 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005257 l(3)SG77 lethal (3) SG77 http://flybase.org/reports/FBgn0005257 - gene - - - l(3)SG77 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0011804 l(3)rQ197 lethal (3) rQ197 http://flybase.org/reports/FBgn0011804 - gene - - - l(3)rQ197 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003678 tdd tiddler http://flybase.org/reports/FBgn0003678 - gene - - - tdd - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile" FBgn0259621 B0995 - http://flybase.org/reports/FBgn0259621 gene - - - B0995 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing,antennal segment,leg,arista" FBgn0044064 GTD1-1.1 GTD1-1.1 http://flybase.org/reports/FBgn0044064 gene - - - GTD1-1.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000187 bis bistre http://flybase.org/reports/FBgn0000187 - gene - - - bis - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041768 anon-d36 anon-d36 http://flybase.org/reports/FBgn0041768 gene - - - "d36, anon-d36" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011822 pcl pepsinogen-like http://flybase.org/reports/FBgn0011822 "FBgn0013391, FBgn0025377" protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein autoprocessing ; GO:0016540 | inferred from electronic annotation with InterPro:IPR033145 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype - "T2, EG:EG0001.1, CG13374, scbeta, pcl, PCL" "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR033145:Cathepsin E, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG13374 11-Aug-17 DroID_v2017_08 "Drer\nots, Drer\ctsd, Drer\zgc:103530, Drer\zgc:63831, Drer\ren" "Scer\YGL258W-A, Scer\MKC7, Scer\PEP4, Scer\YPS5, Scer\YPS7, Scer\YPS1, Scer\BAR1, Scer\YPS3, Scer\YPS6" "Cele\asp-7, Cele\asp-15, Cele\asp-3, Cele\asp-5, Cele\asp-9, Cele\asp-6, Cele\asp-12, Cele\asp-13, Cele\asp-2, Cele\asp-1, Cele\asp-8, Cele\asp-17, Cele\asp-10, Cele\asp-14, Cele\asp-18, Cele\asp-19, Cele\asp-4, Cele\asp-16" "Xtro\pgc, Xtro\ren, Xtro\napsa, Xtro\pga4, Xtro\LOC496913, Xtro\ctse, Xtro\ctsd, Xtro\bace1, Xtro\bace2" "Mmus\Ren2, Mmus\Pga5, Mmus\Cym, Mmus\Ctse, Mmus\Bace2, Mmus\Ren1, Mmus\Bace1, Mmus\Ctsd, Mmus\Pgc, Mmus\Napsa" "Hsap\BACE1, Hsap\PGA5, Hsap\REN, Hsap\PGC, Hsap\PGA3, Hsap\CTSD, Hsap\NAPSA, Hsap\PGA4, Hsap\CTSE, Hsap\BACE2" "lethal - all die during larval stage,recessive,planar polarity defective,somatic clone" "wing margin,somatic clone,wing hair" FBgn0035755 CG14830 - http://flybase.org/reports/FBgn0035755 protein_coding_gene - - - CG14830 - CG14830 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08876 K 0.222560701 0.270460876 -1.482717183 0.017707489 -0.457998003 -1.550117265 FBgn0034510 CG13426 - http://flybase.org/reports/FBgn0034510 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from electronic annotation with InterPro:IPR008158 protein targeting ; GO:0006605 | inferred from electronic annotation with InterPro:IPR001901 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001901, InterPro:IPR008158" CG13426 "IPR001901:Protein translocase complex, SecE/Sec61-gamma subunit, IPR008158:Protein translocase SEC61 complex, gamma subunit, IPR023391:Protein translocase SecE domain, IPR022943:Preprotein translocase subunit SecE" CG13426 11-Aug-17 DroID_v2017_08 Drer\sec61g "Scer\CHL4, Scer\SSS1" Cele\emo-1 Xtro\sec61g "Mmus\Gm4184, Mmus\Sec61g" Hsap\SEC61G "viable,body color defective" mesothoracic tergum FBgn0267866 CR46154 - http://flybase.org/reports/FBgn0267866 pseudogene_attribute - - - CR46154 - CR46154 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001721 l(1)ESHS42 lethal (1) ESHS42 http://flybase.org/reports/FBgn0001721 - gene - - - l(1)ESHS42 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060890 l(3)S044626 lethal (3) S044626 http://flybase.org/reports/FBgn0060890 gene - - - "0446/28, 0446/26, l(3)S044628b, l(3)S044626" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038348 AOX2 Aldehyde oxidase 2 http://flybase.org/reports/FBgn0038348 protein_coding_gene "electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001041 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR006058 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR016166 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR016208 xanthine dehydrogenase activity ; GO:0004854 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 aldehyde oxidase activity ; GO:0004031 | inferred from mutant phenotype flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000225632" oxidation-reduction process ; GO:0055114 | inferred from mutant phenotype xanthine catabolic process ; GO:0009115 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 cellular aldehyde metabolic process ; GO:0006081 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 "CG18519, DmAO2, AOX2" "IPR000674:Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR002346:Molybdopterin dehydrogenase, FAD-binding, IPR002888:[2Fe-2S]-binding, IPR005107:CO dehydrogenase flavoprotein, C-terminal, IPR006058:2Fe-2S ferredoxin, iron-sulphur binding site, IPR008274:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding, IPR016166:FAD-binding, type 2, IPR016169:CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR016208:Aldehyde oxidase/xanthine dehydrogenase, IPR016167:FAD-binding, type 2, subdomain 1, IPR012675:Beta-grasp domain" CG18519 11-Aug-17 DroID_v2017_08 "Drer\xdh, Drer\aox5, Drer\aox6" - "Cele\gad-3, Cele\F15E6.6, Cele\F55B11.1" Xtro\xdh "Mmus\Xdh, Mmus\Aox1, Mmus\Aox4, Mmus\Aox2, Mmus\Aox3" "Hsap\AOX1, Hsap\XDH" FBgn0262262 mir-997-1 mir-997-1 stem loop http://flybase.org/reports/FBgn0262262 miRNA_gene - - - "CR42969, miR-997, miR997, miR-997-1, mir-997-1, dme-mir-997-1, mir-997, hp-mir-997-1" - CR42969 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263522 mir-4982 mir-4982 stem loop http://flybase.org/reports/FBgn0263522 miRNA_gene - - - "mir-4982, dme-mir-4982, CR43507" - CR43507 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002719 Men Malic enzyme http://flybase.org/reports/FBgn0002719 "FBgn0038081, FBgn0062124" protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NAD+) activity ; GO:0004471 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302, InterPro:IPR015884 malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:0004473 | inferred from direct assay malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:0004473 | inferred from mutant phenotype" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302, InterPro:IPR015884 malate metabolic process ; GO:0006108 | inferred from mutant phenotype pyruvate metabolic process ; GO:0006090 | inferred from biological aspect of ancestor with PANTHER:PTN000601050 sleep ; GO:0030431 | inferred from mutant phenotype regulation of cell death ; GO:0010941 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001157886 "ME, CG10120, Me, MDH, Mdh-NADP, anon-WO0118547.278, Men, men, mem, MEN" "IPR001891:Malic oxidoreductase, IPR012301:Malic enzyme, N-terminal domain, IPR012302:Malic enzyme, NAD-binding, IPR015884:Malic enzyme, conserved site, IPR016040:NAD(P)-binding domain" CG10120 11-Aug-17 DroID_v2017_08 "Drer\me1, Drer\me3, Drer\LOC101882012, Drer\me2" Scer\MAE1 Cele\men-1 "Xtro\me3, Xtro\me1, Xtro\me2" "Mmus\Me1, Mmus\Me3, Mmus\Me2" "Hsap\ME1, Hsap\ME3, Hsap\ME2" "viable,visible,long lived,sleep defective,poor,fertile,electrophoretic variant,fast,intermediate,slow" "germline cell,male,eye" DRSC22694 I -2.491778434 -0.78040352 -0.604042791 -0.665376059 0.461028839 0.110123436 FBgn0005578 Ae Aechna http://flybase.org/reports/FBgn0005578 - gene - - - Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" wing FBgn0017463 TfIIH-66 Transcription factor IIH-66kD http://flybase.net/reports/FBgn0017463.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TfIIH, TFIIH" 11-Aug-17 DroID_v2017_08 FBgn0065855 l(2)SH0298 lethal (2) SH0298 http://flybase.org/reports/FBgn0065855 gene - - - "l(2)SH0298, l(2)SH2 0298" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005285 M(3)x Minute (3) x http://flybase.org/reports/FBgn0005285 - gene - - - M(3)x - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible" macrochaeta FBgn0002360 l(3)87Eh lethal (3) 87Eh http://flybase.org/reports/FBgn0002360 - gene - - - "m116, l(3)m116, l(3)87Eh" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034568 CG3216 - http://flybase.org/reports/FBgn0034568 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 receptor activity ; GO:0004872 | inferred from sequence or structural similarity with Gyc76C guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 protein kinase activity ; GO:0004672 | NOT inferred from key residues guanylate cyclase activity ; GO:0004383 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from sequence or structural similarity with Gyc76C signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 cGMP-mediated signaling ; GO:0019934 | inferred from sequence or structural similarity with Gyc76C protein phosphorylation ; GO:0006468 | NOT inferred from key residues "guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Gyc76C" "GYC, CG3216" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001170:Adenylyl cyclase class-4/guanylyl cyclase, IPR001828:Receptor, ligand binding region, IPR011009:Protein kinase-like domain, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase, IPR000719:Protein kinase domain, IPR028082:Periplasmic binding protein-like I, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR011645:Haem NO binding associated" CG3216 11-Aug-17 DroID_v2017_08 "Drer\npr1b, Drer\gc3, Drer\si:ch73-139e5.4, Drer\gucy2c, Drer\npr2, Drer\gucy2g, Drer\si:dkey-37g12.1, Drer\ints3, Drer\npr1a, Drer\gc2, Drer\gucy2f, Drer\npr3" - "Cele\gcy-28, Cele\gcy-7, Cele\gcy-22, Cele\gcy-1, Cele\gcy-19, Cele\gcy-5, Cele\gcy-6, Cele\gcy-3, Cele\gcy-12, Cele\gcy-13, Cele\gcy-4, Cele\gcy-21, Cele\gcy-2, Cele\gcy-14, Cele\Y92H12A.4, Cele\gcy-17" "Xtro\gucy2f, Xtro\gucy2c, Xtro\gucy2d, Xtro\npr3, Xtro\npr1" "Mmus\Npr3, Mmus\Gucy2e, Mmus\Ints3, Mmus\Gucy2d, Mmus\Gucy2f, Mmus\Gucy2c, Mmus\Npr1, Mmus\Gucy2g, Mmus\Npr2" "Hsap\INTS3, Hsap\NPR3, Hsap\GUCY2F, Hsap\GUCY2D, Hsap\NPR1, Hsap\NPR2, Hsap\GUCY2C" viable FBgn0060861 l(3)S047716 lethal (3) S047716 http://flybase.org/reports/FBgn0060861 gene - - - "0477/16, l(3)S047716" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011928 tRNA:iMet-CAT-1-5 transfer RNA:initiator Methionine-CAT 1-5 http://flybase.org/reports/FBgn0011928 "FBgn0003814, FBgn0052144, FBgn0060144" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "CR32144, AE002602.trna23-MetCAT, tRNA:M:CAT:AE002602-b, tRNA:met3:70Fb, tRNA[Met-ATG], chr3L.trna28-MetCAT, tRNA-iMet-CAT-1-5, tRNA:iMet-CAT-1-5, tRNA:M3:70Fb" - CR32144 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040526 CG11602 - http://flybase.org/reports/FBgn0040526 protein_coding_gene - - - CG11602 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030954 CCKLR-17D3 Cholecystokinin-like receptor at 17D3 http://flybase.org/reports/FBgn0030954 protein_coding_gene gastrin receptor activity ; GO:0015054 | inferred from electronic annotation with InterPro:IPR000314 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000314, InterPro:IPR009126 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000314, InterPro:IPR009126, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "CG6894, CG6881, DSK-R1, CG6861, anon-WO0170980.65, anon-WO0170980.64, anon-WO0131005.21, CG32540, CCKLR-17D3, CCKLR-D3, DskR-1, SK-R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000314:Gastrin receptor, IPR009126:Cholecystokinin receptor, IPR017452:GPCR, rhodopsin-like, 7TM" CG32540 11-Aug-17 DroID_v2017_08 "Drer\LOC100331465, Drer\cckar, Drer\si:dkey-1h24.2" - "Cele\ckr-1, Cele\R13H4.7, Cele\ckr-2, Cele\C34B4.3" Xtro\cckar "Mmus\Cckar, Mmus\Cckbr" "Hsap\CCKBR, Hsap\CCKAR" viable DRSC20015 IK 0.414043394 1.562345011 0.187170275 0.628441402 1.579028434 2.087046909 FBgn0069181 mcl(2)Z0756 mcl(2)Z0756 http://flybase.org/reports/FBgn0069181 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z0756 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0043781 Burdock\pol Burdock element pol http://flybase.org/reports/FBgn0043781 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001969 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001969 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - Burdock\pol "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR001969:Aspartic peptidase, active site, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086681 Mst36Fa Male-specific transcript 36Fa http://flybase.org/reports/FBgn0086681 protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "mst36Fa, CG15165, CG31801, Mst36Fa" - CG31801 11-Aug-17 DroID_v2017_08 - - - - - - male semi-fertile FBgn0259553 B2012 - http://flybase.org/reports/FBgn0259553 gene - - - B2012 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" antennal segment FBgn0031078 Nup205 Nucleoporin 205kD http://flybase.org/reports/FBgn0031078 protein_coding_gene structural constituent of nuclear pore ; GO:0017056 | inferred from sequence or structural similarity with SGD:S000003576 structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000772288 centrosome organization ; GO:0051297 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype nuclear pore organization ; GO:0006999 | inferred from sequence or structural similarity with SGD:S000003576 nuclear pore organization ; GO:0006999 | inferred from biological aspect of ancestor with PANTHER:PTN000772288 nuclear pore inner ring ; GO:0044611 | inferred from sequence or structural similarity with SGD:S000003576 nuclear pore inner ring ; GO:0044611 | inferred from biological aspect of ancestor with PANTHER:PTN000772288 cytoplasm ; GO:0005737 | inferred from direct assay "CG11943, anon-EST:Posey281, Ov4, nup205, Nup205" IPR021827:Nucleoporin Nup186/Nup192/Nup205 CG11943 11-Aug-17 DroID_v2017_08 Drer\nup205 Scer\NUP192 Cele\npp-3 Xtro\nup205 Mmus\Nup205 Hsap\NUP205 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,gravitaxis defective" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC19432 E 0.558450567 -0.888722566 0.161035721 1.579147723 0.297141831 -0.173698284 FBgn0000788 fs(1)C4 female sterile (1) C4 http://flybase.org/reports/FBgn0000788 - gene - - - fs(1)C4 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "chorion,ovary" FBgn0086027 snoRNA:Or-CD1 - http://flybase.org/reports/FBgn0086027 snoRNA_gene - - - "snoRNA:Or-CD1, orphan CD1, DmOr_cd1, CR34656, snoRNA:OR-CD1" - CR34656 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030524 CG10993 - http://flybase.org/reports/FBgn0030524 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000472 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000480 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 small-subunit processome assembly ; GO:0034462 | inferred from biological aspect of ancestor with PANTHER:PTN000267771" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 "BcDNA:GH23064, CG10993" "IPR000504:RNA recognition motif domain, IPR034353:ABT1/ESF2, RNA recognition motif" CG10993 11-Aug-17 DroID_v2017_08 Drer\abt1 Scer\ESF2 Cele\F57B10.8 Xtro\abt1 Mmus\Abt1 Hsap\ABT1 viable FBgn0069440 E(zip)31-6 E(zip)31-6 http://flybase.org/reports/FBgn0069440 gene - - - "31-6, E(zip)31-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,visible" leg FBgn0005750 l(1)TK303 lethal (1) TK303 http://flybase.org/reports/FBgn0005750 - gene - - - "l303, l(1)TK303" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" eye FBgn0002673 twe twine http://flybase.org/reports/FBgn0002673 FBgn0016862 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR000751 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity positive regulation of cell cycle G2/M phase transition ; GO:1902751 | inferred from electronic annotation with InterPro:IPR000751 protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000751 spermatogenesis ; GO:0007283 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity protein dephosphorylation ; GO:0006470 | non-traceable author statement embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype meiotic nuclear envelope disassembly ; GO:0051078 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | traceable author statement regulation of meiotic cell cycle ; GO:0051445 | inferred from mutant phenotype meiotic G2/MI transition ; GO:0008315 | traceable author statement regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | inferred from mutant phenotype spindle ; GO:0005819 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "twe, twn, Cdc25, CG4965, TWINE, cdc25, l(2)35Fh, BG:DS02740.1, mat(2)synHB5, mat(2)syn[HB5], mat(2)syn-A, Twe, twine" "IPR000751:M-phase inducer phosphatase, IPR001763:Rhodanese-like domain" CG4965 11-Aug-17 DroID_v2017_08 "Drer\cdc25d, Drer\cdc25b" "Scer\MIH1, Scer\ARR2, Scer\YCH1" "Cele\cdc-25.3, Cele\cdc-25.1, Cele\cdc-25.4, Cele\cdc-25.2" "Xtro\cdc25c, Xtro\cdc25b, Xtro\cdc25a" "Mmus\Cdc25c, Mmus\Cdc25b, Mmus\Cdc25a" "Hsap\CDC25A, Hsap\CDC25C, Hsap\CDC25B" " adult stage | male , adult stage && oogenesis stage , spermatogenesis && adult stage , adult stage && oogenesis stage | stage >S6 , embryonic stage | early " " testis

, nurse cell

, oocyte

, spermatocyte

, primary spermatocyte cyst

" "meiotic cell cycle defective,viable,male sterile,recessive,visible,female fertile,mitotic cell cycle defective,wild-type,male,female,female sterile,cytokinesis defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "spermatocyte,scutellar bristle,ectopic,dorsocentral bristle,trichogen cell,tormogen cell,spindle,pole cell,maternal effect,oocyte,spindle & oocyte,spindle | embryonic stage,yolk,oocyte nucleus,spermatocyte & meiotic cell cycle" FBgn0033661 CG13185 - http://flybase.org/reports/FBgn0033661 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR011704, InterPro:IPR012099" rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000529705 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000529705 cellular response to starvation ; GO:0009267 | inferred from expression pattern "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000529705" "CG18329, CG13185" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR002035:von Willebrand factor, type A, IPR011704:ATPase, dynein-related, AAA domain, IPR003593:AAA+ ATPase domain" CG13185 11-Aug-17 DroID_v2017_08 Drer\mdn1 Scer\MDN1 "Cele\Y6B3B.1, Cele\D1086.9, Cele\F55F10.1" "Xtro\vwa8, Xtro\mdn1" "Mmus\Mdn1, Mmus\Tchhl1, Mmus\Samd15" "Hsap\SAMD15, Hsap\MDN1" "viable,visible" trichogen cell FBgn0029501 Crtp Caldesmon-related protein http://flybase.org/reports/FBgn0029501 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13580, Crtp" - CG13580 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051220 CG31220 - http://flybase.org/reports/FBgn0051220 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "CG16731, SP6, c-SP6, CG31220" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG31220 11-Aug-17 DroID_v2017_08 Drer\masp2 - Cele\try-1 - "Mmus\F10, Mmus\Klk1b1, Mmus\Klk1b5" Hsap\KLK1 viable FBgn0001664 l(1)EA61 lethal (1) EA61 http://flybase.org/reports/FBgn0001664 - gene - - - l(1)EA61 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,polyphasic" FBgn0050468 Ir52c Ionotropic receptor 52c http://flybase.org/reports/FBgn0050468 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG12961, DmelIR52c, CG30468, Ir52c, IR52c" - CG30468 11-Aug-17 DroID_v2017_08 - - Cele\glr-7 - - Hsap\GRIK3 FBgn0020797 ochre ochre http://flybase.org/reports/FBgn0020797 - gene - - - ochre - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0267321 CR45757 - http://flybase.org/reports/FBgn0267321 non_protein_coding_gene - - - CR45757 - CR45757 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085374 CG34345 - http://flybase.org/reports/FBgn0085374 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG34345, CG11053, BP1012, CG34009" "IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG34345 11-Aug-17 DroID_v2017_08 "Drer\zgc:152670, Drer\p4htm, Drer\zgc:158254, Drer\p4ha3, Drer\p4ha1b, Drer\p4ha2, Drer\p4ha1a" - "Cele\phy-3, Cele\phy-2, Cele\phy-4, Cele\C14E2.4, Cele\Y43F8B.19" "Xtro\p4ha1, Xtro\p4ha2, Xtro\p4ha3" "Mmus\P4ha3, Mmus\P4htm, Mmus\P4ha2, Mmus\P4ha1" "Hsap\P4HA2, Hsap\P4HA3, Hsap\P4HTM, Hsap\P4HA1" "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,wing" FBgn0004409 het-rep1 heterochromatic repeat 1 http://flybase.org/reports/FBgn0004409 - repeat_region - - - het-rep1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085320 CG34291 - http://flybase.org/reports/FBgn0085320 protein_coding_gene - - - CG34291 - CG34291 11-Aug-17 DroID_v2017_08 - - Cele\C17E4.4 - - - FBgn0014074 Tsc Triple sex combs http://flybase.org/reports/FBgn0014074 - gene - - - Tsc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031764 CG9107 - http://flybase.org/reports/FBgn0031764 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000324102 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000324102 cellular response to starvation ; GO:0009267 | inferred from expression pattern CURI complex ; GO:0032545 | inferred from biological aspect of ancestor with PANTHER:PTN000324102 UTP-C complex ; GO:0034456 | inferred from biological aspect of ancestor with PANTHER:PTN000324102 "CG9107, Rrp7" "IPR024326:Ribosomal RNA-processing protein 7, IPR000504:RNA recognition motif domain" CG9107 11-Aug-17 DroID_v2017_08 Drer\rrp7a Scer\RRP7 Cele\ZC434.4 Xtro\rrp7a Mmus\Rrp7a Hsap\RRP7A FBgn0031515 CG9664 - http://flybase.org/reports/FBgn0031515 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 olfactory behavior ; GO:0042048 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 CG9664 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9664 11-Aug-17 DroID_v2017_08 "Drer\abcg1, Drer\abcg2c, Drer\abcg2a, Drer\abcg2b, Drer\abcg8, Drer\abcg5, Drer\abcg4b, Drer\abcg4a" "Scer\ADP1, Scer\SNQ2, Scer\PDR18, Scer\YOL075C, Scer\PDR15, Scer\PDR10" "Cele\wht-8, Cele\abch-1, Cele\wht-6, Cele\wht-7, Cele\wht-3, Cele\wht-4, Cele\wht-1" "Xtro\abcg8, Xtro\abcg5" "Mmus\Abcg5, Mmus\Abcg3, Mmus\Abcg2, Mmus\Abcg1, Mmus\Abcg8, Mmus\Abcg4" "Hsap\ABCG8, Hsap\ABCG2, Hsap\ABCG4, Hsap\ABCG5, Hsap\ABCG1" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0050461 CG30461 - http://flybase.org/reports/FBgn0050461 protein_coding_gene - - - "CG33142, BcDNA:AT13932, CR30461, CG30461" - CG30461 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0014214 l(2)31Bb lethal (2) 31Bb http://flybase.org/reports/FBgn0014214 - gene - - - l(2)31Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031006 rictor rapamycin-insensitive companion of Tor http://flybase.org/reports/FBgn0031006 protein_coding_gene enzyme activator activity ; GO:0008047 | inferred from biological aspect of ancestor with PANTHER:PTN000329282 TOR signaling ; GO:0031929 | inferred from electronic annotation with InterPro:IPR028268 actin cytoskeleton reorganization ; GO:0031532 | inferred from biological aspect of ancestor with PANTHER:PTN000329282 cellular response to starvation ; GO:0009267 | inferred from direct assay stress granule assembly ; GO:0034063 | inferred from mutant phenotype establishment of cell polarity ; GO:0030010 | inferred from biological aspect of ancestor with PANTHER:PTN000329282 establishment or maintenance of actin cytoskeleton polarity ; GO:0030950 | inferred from biological aspect of ancestor with PANTHER:PTN000329282 synaptic growth at neuromuscular junction ; GO:0051124 | inferred from genetic interaction with Rheb regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype regulation of phosphorylation ; GO:0042325 | inferred from biological aspect of ancestor with PANTHER:PTN000329282 regulation of actin cytoskeleton organization ; GO:0032956 | inferred from biological aspect of ancestor with PANTHER:PTN000329282 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | inferred from mutant phenotype positive regulation of protein kinase B signaling ; GO:0051897 | inferred from biological aspect of ancestor with PANTHER:PTN000329282 TORC2 complex ; GO:0031932 | inferred from biological aspect of ancestor with PANTHER:PTN000329282 "rictor, dRictor, CG8002, dRic, Rictor, 8002" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR029452:Rapamycin-insensitive companion of mTOR, domain 5, IPR029453:Rapamycin-insensitive companion of mTOR, domain 4, IPR029451:Rapamycin-insensitive companion of mTOR, middle domain, IPR028268:Pianissimo family, IPR028267:Rapamycin-insensitive companion of mTOR, N-terminal domain" CG8002 11-Aug-17 DroID_v2017_08 "Drer\rictora, Drer\rictorb" Scer\TSC11 Cele\rict-1 Xtro\rictor Mmus\Rictor Hsap\RICTOR "small body,viable,fertile,neuroanatomy defective,cell autonomous,somatic clone,developmental rate defective,partially lethal - majority die" "wing,class IV dendritic arborizing neuron,dendrite,cell autonomous,somatic clone,dendrite | cell autonomous | somatic clone,ventral multidendritic neuron vdaB,abdominal anterior ventral multidendritic neuron vdaa,dorsal multidendritic neuron ddaC,embryonic/larval neuromuscular junction" FBgn0086378 Alg-2 Apoptosis-linked gene-2 http://flybase.org/reports/FBgn0086378 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | inferred from biological aspect of ancestor with PANTHER:PTN000021568 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000021568 positive regulation of JNK cascade ; GO:0046330 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000021568 "CG40410, Alg-2, CG17661, ALG-2, DALG-2" "IPR018247:EF-Hand 1, calcium-binding site, IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG40410 11-Aug-17 DroID_v2017_08 "Drer\capns1a, Drer\sri, Drer\pef1, Drer\capns1b, Drer\zgc:92027, Drer\pdcd6" Scer\PEF1 Cele\M04F3.4 "Xtro\pdcd6, Xtro\pef1, Xtro\gca, Xtro\sri, Xtro\capns2" "Mmus\Pdcd6, Mmus\Capns1, Mmus\Sri, Mmus\Capns2, Mmus\Gca, Mmus\Pef1, Mmus\Capn13" "Hsap\PDCD6, Hsap\GCA, Hsap\SRI, Hsap\PEF1, Hsap\CAPN13, Hsap\CAPNS1" FBgn0012025 tRNA:Tyr-GTA-1-7 transfer RNA:Tyrosine-GTA 1-7 http://flybase.org/reports/FBgn0012025 "FBgn0003849, FBgn0012014, FBgn0051433, FBgn0060004" tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "Tyr-tRNA T85b, 85Ab, tRNA-Tyr, tRNA[Tyr][[1gamma]], AE002708.trna58-TyrGTA, tRNA:Y, tRNA:Y:GTA:AE002708-b, CR31433, tRNA:tyr1:85Ab, tRNA[Tyr], chr3R.trna64-TyrGTA, tRNA:Tyr-GTA-1-7, tRNA:Y1:85Ab, tRNA-Tyr-GTA-1-7, UAC" - CR31433 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038486 CG5265 - http://flybase.org/reports/FBgn0038486 protein_coding_gene carnitine O-acetyltransferase activity ; GO:0004092 | inferred from sequence or structural similarity with UniProtKB:P43155 carnitine metabolic process ; GO:0009437 | inferred from sequence or structural similarity with UniProtKB:P43155 fatty acid metabolic process ; GO:0006631 | inferred from sequence or structural similarity with UniProtKB:P43155 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:P43155 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:P43155 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with UniProtKB:P43155 peroxisome ; GO:0005777 | inferred from sequence model CG5265 IPR000542:Acyltransferase ChoActase/COT/CPT CG5265 11-Aug-17 DroID_v2017_08 "Drer\cpt1ab, Drer\crot, Drer\cratb, Drer\LOC101884918, Drer\zgc:154046, Drer\chata, Drer\si:ch211-256m1.8, Drer\cpt1b, Drer\cpt1cb, Drer\cpt1aa, Drer\crata" Scer\CAT2 "Cele\B0395.3, Cele\cha-1, Cele\W03F9.4" "Xtro\crat.2, Xtro\chat, Xtro\LOC100490391, Xtro\cpt1b, Xtro\crat.1" "Mmus\Cpt1c, Mmus\Crot, Mmus\Cpt1b, Mmus\Chat, Mmus\Cpt1a, Mmus\Crat, Mmus\Chkb" "Hsap\CRAT, Hsap\CPT1B, Hsap\CROT, Hsap\CPT1C, Hsap\CHAT, Hsap\CPT1A, Hsap\CHKB" "viable,visible" mesothoracic tergum FBgn0043562 Su(hh)V Su(hh)V http://flybase.org/reports/FBgn0043562 gene - - - Su(hh)V - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050098 CG30098 - http://flybase.org/reports/FBgn0050098 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern" cellular_component ; GO:0005575 | no biological data available CG30098 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG30098 11-Aug-17 DroID_v2017_08 - - Cele\try-3 - - - FBgn0027378 MRG15 MORF-related gene 15 http://flybase.org/reports/FBgn0027378 FBgn0024526 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay methylated histone binding ; GO:0035064 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Cap-H2 "histone H2A acetylation ; GO:0043968 | inferred from biological aspect of ancestor with PANTHER:PTN000093964 histone acetylation ; GO:0016573 | inferred from direct assay histone H4 acetylation ; GO:0043967 | inferred from biological aspect of ancestor with PANTHER:PTN000093964 chromosome separation ; GO:0051304 | inferred from mutant phenotype inferred from genetic interaction with glu, Cap-H2 histone exchange ; GO:0043486 | inferred from direct assay chromatin silencing ; GO:0006342 | inferred from mutant phenotype histone deacetylation ; GO:0016575 | inferred from biological aspect of ancestor with PANTHER:PTN000093964 chromosome organization ; GO:0051276 | inferred from mutant phenotype inferred from genetic interaction with Cap-H2" histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "dMrg15, CG6363, dMRG15, Dmrg15, DmMRG15, l(3)j6A3, MRG15, Mrg15" "IPR000953:Chromo/chromo shadow domain, IPR008676:MRG, IPR016197:Chromo domain-like, IPR025995:RNA binding activity-knot of a chromodomain, IPR026541:MRG domain" CG6363 11-Aug-17 DroID_v2017_08 "Drer\arid4a, Drer\morf4l1, Drer\arid4b" Scer\EAF3 "Cele\cec-7, Cele\mrg-1" "Xtro\arid4a, Xtro\arid4b, Xtro\morf4l1" "Mmus\Msl3, Mmus\Morf4l2, Mmus\Msl3l2, Mmus\Arid4b, Mmus\Morf4l1, Mmus\Morf4l1b, Mmus\Arid4a" "Hsap\ARID4A, Hsap\MORF4L2, Hsap\ARID4B, Hsap\MORF4L1, Hsap\MSL3" "female semi-sterile,short lived,lethal,recessive,suppressor of variegation,dominant,viable,non-suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage,male limited" FBgn0050094 CG30094 - http://flybase.org/reports/FBgn0050094 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000058 - - "CG15700, BcDNA:SD13256, CG30094" "IPR000058:Zinc finger, AN1-type" CG30094 11-Aug-17 DroID_v2017_08 Drer\ighmbp2 Scer\HCS1 "Cele\eri-7, Cele\Y106G6D.5" Xtro\ighmbp2 Mmus\Ighmbp2 Hsap\IGHMBP2 "viable,fertile" FBgn0262023 CG42834 - http://flybase.org/reports/FBgn0262023 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42834 - CG42834 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041598 l(2)Ia lethal (2) Ia http://flybase.org/reports/FBgn0041598 gene - - - l(2)Ia - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022284 l(2)IR12 lethal (2) IR12 http://flybase.org/reports/FBgn0022284 - gene - - - l(2)IR12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039109 CG10365 - http://flybase.org/reports/FBgn0039109 protein_coding_gene Notch binding ; GO:0005112 | inferred from sequence or structural similarity with MGI:MGI:1916315 gamma-glutamylcyclotransferase activity ; GO:0003839 | inferred from biological aspect of ancestor with PANTHER:PTN001742855 neurogenesis ; GO:0022008 | inferred from sequence or structural similarity with MGI:MGI:1916315 glutathione catabolic process ; GO:0006751 | inferred from biological aspect of ancestor with PANTHER:PTN001742855 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001742855 trans-Golgi network ; GO:0005802 | inferred from sequence or structural similarity with MGI:MGI:1916315 "anon-WO0118547.386, CG10365" "IPR006840:Glutathione-specific gamma-glutamylcyclotransferase, IPR013024:Gamma-glutamyl cyclotransferase-like" CG10365 11-Aug-17 DroID_v2017_08 "Drer\chac1, Drer\chac2" Scer\GCG1 Cele\F22F7.7 Xtro\chac2 "Mmus\Chac1, Mmus\Chac2" "Hsap\CHAC2, Hsap\CHAC1" viable FBgn0037630 Ir85a Ionotropic receptor 85a http://flybase.org/reports/FBgn0037630 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir85a, CT32618, CG11775, DmelIR85a, IR85a" IPR001320:Ionotropic glutamate receptor CG11775 11-Aug-17 DroID_v2017_08 "Drer\grid1a, Drer\grid1b, Drer\LOC100537813" - Cele\glr-8 - "Mmus\Grik4, Mmus\Grid1" "Hsap\GRID1, Hsap\GRID2" viable FBgn0005074 fs(2)OW215 female sterile (2) OW215 http://flybase.org/reports/FBgn0005074 - gene - - - fs(2)OW215 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030507 CG11164 - http://flybase.org/reports/FBgn0030507 protein_coding_gene - - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR019024 CG11164 "IPR019024:Ribonuclease H2, subunit B" CG11164 11-Aug-17 DroID_v2017_08 Drer\rnaseh2b - Cele\F21D5.6 Xtro\rnaseh2b Mmus\Rnaseh2b Hsap\RNASEH2B "viable,fertile" DRSC19392 K 0.008772921 0.034548103 -0.264672176 0.299891017 -0.509876431 1.507405748 FBgn0264978 Slh SLY-1 homologous http://flybase.org/reports/FBgn0264978 protein_coding_gene SNARE binding ; GO:0000149 | inferred from sequence or structural similarity syntaxin binding ; GO:0019905 | inferred from sequence or structural similarity with UniProtKB:Q62991 "vesicle docking involved in exocytosis ; GO:0006904 | inferred from electronic annotation with InterPro:IPR001619 cell morphogenesis ; GO:0000902 | inferred from mutant phenotype regulation of ER to Golgi vesicle-mediated transport ; GO:0060628 | inferred from sequence or structural similarity with UniProtKB:Q62991 response to hypoxia ; GO:0001666 | inferred from sequence or structural similarity with UniProtKB:Q62991 phagocytosis ; GO:0006909 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap post-Golgi vesicle-mediated transport ; GO:0006892 | inferred from sequence or structural similarity with UniProtKB:Q62991 response to toxic substance ; GO:0009636 | inferred from sequence or structural similarity with UniProtKB:Q8WVM8 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with UniProtKB:Q62991 neurogenesis ; GO:0022008 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity" Golgi transport complex ; GO:0017119 | colocalizes_with inferred from sequence or structural similarity with UniProtKB:Q62991 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q62991 Golgi-associated vesicle ; GO:0005798 | inferred from sequence or structural similarity with UniProtKB:Q62991 SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay cis-Golgi network ; GO:0005801 | inferred from sequence or structural similarity with UniProtKB:Q8WVM8 "Slh, Sly1, slh, CG3539, Sly1p, d-sly, Sly, SLY1, CG15393" IPR001619:Sec1-like protein CG3539 11-Aug-17 DroID_v2017_08 Drer\scfd1 Scer\SLY1 Cele\sly-1 Xtro\scfd1 Mmus\Scfd1 Hsap\SCFD1 embryonic stage | stage >=14 " embryonic/larval salivary gland

, embryonic/larval esophagus

, embryonic/larval midgut | posterior

" DRSC00789 IE 0.172701001 2.255084099 2.910395869 -1.364833688 -0.391035765 0.648986177 FBgn0041832 Eth-AR315 Eth-AR315 http://flybase.org/reports/FBgn0041832 gene - - - "Eth[AR]315, Eth-AR315" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0053530 Acp53C14c Accessory gland protein 53C14c http://flybase.org/reports/FBgn0053530 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG33530, Acp53C14c, HDC06801" IPR009392:Drosophila ACP53EA CG33530 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029723 Proc-R Proctolin receptor http://flybase.org/reports/FBgn0029723 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from sequence model proctolin receptor activity ; GO:0035236 | inferred from physical interaction with Proc proctolin receptor activity ; GO:0035236 | inferred from direct assay G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay "anon-WO0170980.74, anon-WO0170980.73, CG6986, Proc R, Proc-R, ProcR, PROC-R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM, IPR019427:7TM GPCR, serpentine receptor class w (Srw)" CG6986 11-Aug-17 DroID_v2017_08 - - "Cele\F59B2.13, Cele\H09F14.1, Cele\K03H6.5, Cele\R13H7.2, Cele\frpr-8, Cele\frpr-7, Cele\H23L24.4, Cele\B0334.6, Cele\frpr-10, Cele\K03H6.1, Cele\W10C4.1, Cele\F40A3.7, Cele\D1014.2, Cele\T10E10.3" - "Mmus\Gpr142, Mmus\Gpr139" "Hsap\CCR1, Hsap\GPR139, Hsap\GPR18" adult stage head

viable FBgn0266144 CR44850 - http://flybase.org/reports/FBgn0266144 non_protein_coding_gene - - - CR44850 - CR44850 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267587 CR45925 - http://flybase.org/reports/FBgn0267587 non_protein_coding_gene - - - CR45925 - CR45925 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065808 l(2)SH0389 lethal (2) SH0389 http://flybase.org/reports/FBgn0065808 gene - - - "l(2)SH0389, l(2)SH2 0389" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003030 patulous patulous http://flybase.org/reports/FBgn0003030 - gene - - - "patulous, pa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile,partially" wing FBgn0037296 Prosbeta2R2 Proteasome beta2 subunit-related 2 http://flybase.org/reports/FBgn0037296 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | inferred from sequence or structural similarity with SGD:S000005683" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000005683 "proteasome core complex, beta-subunit complex ; GO:0019774 | inferred from sequence or structural similarity with SGD:S000005683" "Prosbeta2R2, CG12161, beta2R2" "IPR000243:Peptidase T1A, proteasome beta-subunit, IPR001353:Proteasome, subunit alpha/beta, IPR023333:Proteasome B-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG12161 11-Aug-17 DroID_v2017_08 "Drer\zgc:92791, Drer\psmb7, Drer\psmb10" Scer\PUP1 Cele\pbs-2 "Xtro\psmb7.2, Xtro\psmb7" "Mmus\Psmb10, Mmus\Psmb7" "Hsap\PSMB10, Hsap\PSMB7" viable FBgn0014395 tilB touch insensitive larva B http://flybase.org/reports/FBgn0014395 FBgn0031185 protein_coding_gene - "temperature compensation of the circadian clock ; GO:0010378 | inferred from mutant phenotype cilium-dependent cell motility ; GO:0060285 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype axoneme assembly ; GO:0035082 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype" motile cilium ; GO:0031514 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG14620, tilB" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR008978:HSP20-like chaperone" CG14620 11-Aug-17 DroID_v2017_08 "Drer\tlr4bb, Drer\si:dkey-267j14.7, Drer\tlr4ba, Drer\tlr4al, Drer\cep97, Drer\si:ch211-103e16.5, Drer\lrrc23, Drer\lrriq1, Drer\lrrc9, Drer\lrrc61, Drer\ppp1r7, Drer\lrrc17, Drer\drc3, Drer\lrrc6, Drer\lrrcc1, Drer\zgc:91976, Drer\sgms2, Drer\lrguk" "Scer\NUD1, Scer\SDS22" "Cele\F09G8.5, Cele\R02F11.4, Cele\F53B1.2" "Xtro\lrrc49, Xtro\lrrc6, Xtro\sgms2, Xtro\lrrc56, Xtro\sgms1, Xtro\drc3, Xtro\cep97, Xtro\ppp1r7, Xtro\dnal1, Xtro\lrrc23, Xtro\lrrc9, Xtro\lrrcc1, Xtro\samd8" "Mmus\Samd8, Mmus\1810043G02Rik, Mmus\Lrrcc1, Mmus\Lrrc17, Mmus\Dnal1, Mmus\Cep97, Mmus\Sgms2, Mmus\Lrrc61, Mmus\Lrrc46, Mmus\Lrrc43, Mmus\Lrrc56, Mmus\Lrrc6, Mmus\Lrrc48, Mmus\Lrriq1, Mmus\Lrrc49, Mmus\Lrguk, Mmus\Lrrc23, Mmus\Sgms1, Mmus\Ppp1r7, Mmus\Lrrc9, Mmus\Lrriq3" "Hsap\DNAL1, Hsap\CEP97, Hsap\LRRC6, Hsap\C21orf2, Hsap\LRRC43, Hsap\LRRC46, Hsap\SAMD8, Hsap\LRRIQ1, Hsap\LRRCC1, Hsap\DRC3, Hsap\LRRIQ3, Hsap\LRRC23, Hsap\SGMS1, Hsap\SGMS2, Hsap\LRRC61, Hsap\PPP1R7, Hsap\LRRC49, Hsap\LRRC56, Hsap\LRGUK, Hsap\LRRC17" "locomotor behavior defective,locomotor rhythm defective,touch sensitivity defective,recessive,behavior defective,courtship behavior defective,auditory perception defective,male sterile,song defective,neuroanatomy defective,viable" "adult antennal nerve,spermatid axoneme,arista,cilium,scolopidial cilium,Johnston organ" FBgn0025186 ari-2 ariadne 2 http://flybase.org/reports/FBgn0025186 FBgn0010640 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001878 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:690 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from biological aspect of ancestor with PANTHER:PTN000188395" positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:690 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 "CG5709, ari2, l(2)07768, ari-2, AAF46823.1" "IPR001841:Zinc finger, RING-type, IPR002867:IBR domain, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR031127:E3 ubiquitin ligase RBR family" CG5709 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-278j3.3, Drer\rnf144b, Drer\shrprbck1r, Drer\arih2, Drer\rnf19a, Drer\rnf144aa, Drer\rbck1, Drer\rnf19b, Drer\rnf144ab, Drer\arih1, Drer\rnf217, Drer\ankib1b, Drer\ankib1a, Drer\arih1l" Scer\HEL1 "Cele\C27A12.7, Cele\F56D2.2, Cele\F56D2.5, Cele\T12E12.1, Cele\tag-349, Cele\C27A12.6, Cele\ari-1" "Xtro\rnf144a, Xtro\rnf217, Xtro\rnf19a, Xtro\arih2, Xtro\cul9, Xtro\rnf144b" "Mmus\Rnf217, Mmus\Rnf144a, Mmus\Sharpin, Mmus\Rnf19a, Mmus\Rnf19b, Mmus\Cul7, Mmus\Ankib1, Mmus\Arih2, Mmus\Cul9, Mmus\Arih1, Mmus\Rbck1, Mmus\Rnf144b" "Hsap\ARIH1, Hsap\RNF19A, Hsap\RNF217, Hsap\CUL9, Hsap\ARIH2, Hsap\ANKIB1, Hsap\RNF19B, Hsap\RNF144A, Hsap\CUL7, Hsap\RBCK1, Hsap\RNF144B" "viable,fertile,lethal,recessive,neuroanatomy defective,somatic clone,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "neuroblast,somatic clone" DRSC04672 IEK -0.236320795 1.881179688 2.457436611 0.652991621 2.463064756 -0.143321998 FBgn0000868 fs(1)M63 female sterile (1) M63 http://flybase.org/reports/FBgn0000868 - gene - - - fs(1)M63 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0011442 l(3)j13E7 lethal (3) j13E7 http://flybase.org/reports/FBgn0011442 - gene - - - l(3)j13E7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037411 Osi3 Osiris 3 http://flybase.org/reports/FBgn0037411 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi3, CG1150, osi3" IPR012464:Protein of unknown function DUF1676 CG1150 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267742 CR46073 - http://flybase.org/reports/FBgn0267742 non_protein_coding_gene - - - CR46073 - CR46073 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259617 B1510 - http://flybase.org/reports/FBgn0259617 gene - - - B1510 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible tarsal segment FBgn0026347 Su(da[lyh])26H6 Su(da[lyh])26H6 http://flybase.org/reports/FBgn0026347 - gene - - - "Su(lyh), Su(da[lyh]), Su(da[lyh])26H6" - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0025346 anon-11c anon-11c http://flybase.org/reports/FBgn0025346 - gene - - - anon-11c - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022143 l(2)k06113 lethal (2) k06113 http://flybase.org/reports/FBgn0022143 - gene - - - l(2)k06113 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051901 Mur29B Mucin related 29B http://flybase.org/reports/FBgn0051901 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model biological_process ; GO:0008150 | no biological data available extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:LP08232, Mur29B, CG31901" - CG31901 11-Aug-17 DroID_v2017_08 Drer\LOC799879 - - Xtro\spty2d1 Mmus\D6Ertd527e - "viable,fertile" FBgn0011832 Ser12 Serine protease 12 http://flybase.org/reports/FBgn0011832 - protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 wound healing ; GO:0042060 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP92, CG17240, Ser12" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG17240 11-Aug-17 DroID_v2017_08 - - "Cele\svh-1, Cele\try-1" - "Mmus\Prss55, Mmus\Klk14, Mmus\Prss53, Mmus\Egfbp2, Mmus\Klk9, Mmus\Prss36" "Hsap\PRSS57, Hsap\KLK11, Hsap\KLK14, Hsap\PRSS36, Hsap\PRSS53" viable DRSC00786 K 0.372886302 0.164008239 -0.227467698 0.426881724 -0.846291776 -2.227627711 FBgn0039080 Ir94h Ionotropic receptor 94h http://flybase.org/reports/FBgn0039080 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir94h, IR94h, CG17382, DmelIR94h" - CG17382 11-Aug-17 DroID_v2017_08 "Drer\grid1b, Drer\grid1a, Drer\grik2, Drer\LOC100537813, Drer\grik5, Drer\grid2, Drer\LOC100334689" - "Cele\F59E12.8, Cele\glr-6, Cele\glr-3" - "Mmus\Grid2, Mmus\Grik2, Mmus\Grik5, Mmus\Grik3, Mmus\Grid1" "Hsap\GRIK5, Hsap\GRID2, Hsap\GRID1, Hsap\GRIK3, Hsap\GRIK2" viable FBgn0030298 Or10a Odorant receptor 10a http://flybase.org/reports/FBgn0030298 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from direct assay "10a, DOR92, 10B.1, CG17867, Or10a" "IPR004117:Olfactory receptor, insect" CG17867 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,taste perception defective" FBgn0260446 GABA-B-R1 metabotropic GABA-B receptor subtype 1 http://flybase.org/reports/FBgn0260446 protein_coding_gene G-protein coupled GABA receptor activity ; GO:0004965 | inferred from sequence or structural similarity G-protein coupled GABA receptor activity ; GO:0004965 | contributes_to inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with GABA-B-R2 gamma-aminobutyric acid signaling pathway ; GO:0007214 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity negative regulation of adenylate cyclase activity ; GO:0007194 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity G-protein coupled receptor heterodimeric complex ; GO:0038039 | inferred from physical interaction with GABA-B-R2 integral component of plasma membrane ; GO:0005887 | inferred from direct assay "GB1, GABA[[B]]R1, CG15274, D-Gaba1, D-GABA[[B]]R1, BG:DS00929.6, anon-WO0170980.176, anon-WO0170980.175, GABA-B-R1, GABA[[B]], GABA[[B]]R, GABA(B)R1, GABA-BR1, GABA[[B]]-R1" "IPR017978:GPCR family 3, C-terminal, IPR001828:Receptor, ligand binding region, IPR002455:GPCR family 3, GABA-B receptor, IPR002456:GPCR family 3, gamma-aminobutyric acid receptor, type B1, IPR028082:Periplasmic binding protein-like I" CG15274 11-Aug-17 DroID_v2017_08 "Drer\atp1b3a, Drer\atp1b2a, Drer\atp1b1b, Drer\atp1b1a, Drer\atp1b3b, Drer\gpr156, Drer\gabbr1b, Drer\gabbr1a, Drer\atp1b4, Drer\gabbr2, Drer\atp1b2b" - "Cele\gbb-1, Cele\gbb-2" "Xtro\gabbr1, Xtro\gabbr2, Xtro\atp1b2, Xtro\atp4b, Xtro\atp1b3, Xtro\atp1b4, Xtro\atp1b1" "Mmus\Gpr156, Mmus\Atp1b1, Mmus\Gabbr1, Mmus\Atp1b3, Mmus\Atp1b4, Mmus\Atp1b2, Mmus\Atp4b, Mmus\Gabbr2" "Hsap\GABBR2, Hsap\ATP1B4, Hsap\ATP4B, Hsap\GABBR1, Hsap\ATP1B2, Hsap\GPR156, Hsap\ATP1B1, Hsap\ATP1B3" FBgn0263658 CR43649 - http://flybase.org/reports/FBgn0263658 non_protein_coding_gene - - - CR43649 - CR43649 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026358 Su(SuRaf1)1 Su(SuRaf1)1 http://flybase.org/reports/FBgn0026358 - gene - - - "Su[Su(Raf)1]1, Su(SuRaf1)1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004816 fs(2)ltoRU26 female sterile (2) ltoRU26 http://flybase.org/reports/FBgn0004816 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Ru26, fs(2)ltoRU26" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0260861 Trs23 TRAPP subunit 23 http://flybase.org/reports/FBgn0260861 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000002654 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000583159 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000002654 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000583159 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000002654 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity TRAPP complex ; GO:0030008 | inferred from biological aspect of ancestor with PANTHER:PTN000583159 "CG9298, TRS23, Trs23p, Trs23" "IPR007233:Trafficking protein particle complex subunit, IPR011012:Longin-like domain" CG9298 11-Aug-17 DroID_v2017_08 Drer\trappc4 Scer\TRS23 Cele\trpp-4 Xtro\trappc4 Mmus\Trappc4 Hsap\TRAPPC4 DRSC03190 I 0.38319755 1.59979925 1.234167473 0.470031792 -0.230695005 0.632184629 FBgn0053390 5SrRNA:CR33390 5SrRNA:CR33390 http://flybase.org/reports/FBgn0053390 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33390, 5SrRNA:CR33390" - CR33390 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086385 BG01563 - http://flybase.org/reports/FBgn0086385 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01563 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0016922 put::tor put::tor http://flybase.org/reports/FBgn0016922 - engineered_fusion_gene - - - put::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016770 anon-47Aa anon-47Aa http://flybase.org/reports/FBgn0016770 - gene - - - anon-47Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025480 ms(3)nc14 male sterile (3) noncomplementer 14 http://flybase.org/reports/FBgn0025480 - gene - - - ms(3)nc14 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0024658 l(2)k07620 lethal (2) k07620 http://flybase.org/reports/FBgn0024658 - gene - - - "76/20, l(2)k07620" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,wing,trichome" FBgn0035429 CG12017 - http://flybase.org/reports/FBgn0035429 protein_coding_gene - - - CG12017 - CG12017 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004206 l(3)84Ed lethal (3) 84Ed http://flybase.org/reports/FBgn0004206 - gene - - - l(3)84Ed - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053834 His1:CG33834 His1:CG33834 http://flybase.org/reports/FBgn0053834 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33834, His1:CG33834" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33834 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.14, Drer\h1f0, Drer\si:dkey-108k21.21, Drer\zgc:110425, Drer\si:ch211-113a14.24, Drer\zgc:163061, Drer\h1fx, Drer\histh1l, Drer\si:ch73-36p18.1, Drer\zgc:110216, Drer\h1m, Drer\si:dkey-261m9.12, Drer\si:ch1073-159d7.7, Drer\si:dkey-108k21.10, Drer\zgc:153405" Scer\HHO1 "Cele\hil-4, Cele\hil-6, Cele\hil-3, Cele\hil-5, Cele\his-24, Cele\hil-2" Xtro\h1f0 "Mmus\Hist1h1e, Mmus\Hist1h1d, Mmus\H1foo, Mmus\Hist1h1b, Mmus\Hist1h1a, Mmus\Hils1, Mmus\Hist1h1t, Mmus\Hist1h1c, Mmus\H1fnt, Mmus\H1fx" "Hsap\H1FOO, Hsap\HIST1H1B, Hsap\HIST1H1A, Hsap\H1FX, Hsap\HIST1H1E, Hsap\H1F0, Hsap\H1FNT, Hsap\HIST1H1D, Hsap\HIST1H1T, Hsap\HIST1H1C" FBgn0030941 wgn wengen http://flybase.org/reports/FBgn0030941 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W3I9 tumor necrosis factor-activated receptor activity ; GO:0005031 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with egr tumor necrosis factor-activated receptor activity ; GO:0005031 | inferred from mutant phenotype tumor necrosis factor-activated receptor activity ; GO:0005031 | inferred from sequence or structural similarity with HGNC:11916 apoptotic process ; GO:0006915 | non-traceable author statement cell surface receptor signaling pathway ; GO:0007166 | inferred from genetic interaction with egr photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from direct assay negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from genetic interaction with Ank2 neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with Ank2 cell surface ; GO:0009986 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:11916 inferred from direct assay "vader, CG6531, wgn, Wgn, TNFR" IPR001368:TNFR/NGFR cysteine-rich region CG6531 11-Aug-17 DroID_v2017_08 - - - - Mmus\Tnfrsf4 Hsap\TNFRSF4 "neuroanatomy defective,somatic clone,viable,fertile" "lamina,medulla,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R8,somatic clone,lamina plexus | third instar larval stage,medulla | third instar larval stage,lamina plexus,cell non-autonomous | third instar larval stage,cell autonomous | third instar larval stage" FBgn0022317 l(1)D10.2 lethal (1) D10.2 http://flybase.org/reports/FBgn0022317 - gene - - - "D10.2, l(1)D10.2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037546 mAChR-B "muscarinic Acetylcholine Receptor, B-type" http://flybase.org/reports/FBgn0037546 protein_coding_gene G-protein coupled acetylcholine receptor activity ; GO:0016907 | inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity with mAChR-A "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mAChR-A synaptic transmission, cholinergic ; GO:0007271 | inferred from biological aspect of ancestor with PANTHER:PTN001205349 G-protein coupled acetylcholine receptor signaling pathway ; GO:0007213 | inferred from direct assay" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mAChR-A "anon-WO0170980.91, anon-WO0170980.92, CG7918, mAcR-CG7918, mAChR-B, mAChR B, Dm-mAChR-B" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG7918 11-Aug-17 DroID_v2017_08 "Drer\hrh1, Drer\hrh4, Drer\LOC100331077, Drer\hrh3" - "Cele\ser-6, Cele\gar-2, Cele\gar-1" "Xtro\hrh3, Xtro\hrh1" "Mmus\Hrh4, Mmus\Hrh1, Mmus\Gpr162, Mmus\Hrh3" "Hsap\HRH1, Hsap\GPR153, Hsap\HRH4, Hsap\HRH3" DRSC16345 IE 0.384868772 -2.627452625 -0.649298535 -4.683847635 1.055493342 1.212806216 FBgn0029088 disp dispatched http://flybase.org/reports/FBgn0029088 protein_coding_gene - exocytosis ; GO:0006887 | traceable author statement pole cell migration ; GO:0007280 | inferred from genetic interaction with hh inferred from genetic interaction with Hmgcr smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000731 membrane ; GO:0016020 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "anon-WO0146227.1, CG2019, disp, Disp" "IPR000731:Sterol-sensing domain, IPR030223:Protein dispatched, IPR003392:Protein patched/dispatched" CG2019 11-Aug-17 DroID_v2017_08 "Drer\disp1, Drer\disp2, Drer\si:dkey-32e23.6" - "Cele\ptr-16, Cele\che-14, Cele\ptr-3, Cele\ptd-2, Cele\ptr-17" "Xtro\disp2, Xtro\ptchd2.2, Xtro\disp1" "Mmus\Disp1, Mmus\Ptchd2, Mmus\Disp2" "Hsap\DISP3, Hsap\DISP2, Hsap\DISP1" " larval stage , embryonic stage " " dorsal mesothoracic disc | ubiquitous

, embryo | ubiquitous

" "lethal,recessive,rescuable maternal effect,segment polarity phenotype,wild-type,visible,somatic clone,viable" "denticle,germline clone,maternal effect,embryonic/first instar larval cuticle,denticle belt,ventral,wing,somatic clone,1st posterior cell,eye" FBgn0020571 anon-85Ca anon-85Ca http://flybase.org/reports/FBgn0020571 - gene - - - "2.2kb, anon-85Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030269 CDK2AP1 CDK2-associated protein 1 http://flybase.org/reports/FBgn0030269 protein_coding_gene DNA polymerase binding ; GO:0070182 | inferred from sequence or structural similarity with HGNC:14002 positive regulation of protein phosphorylation ; GO:0001934 | inferred from sequence or structural similarity with HGNC:14002 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:14002 "anon-WO03040301.144, CDK2AP1, DOC1, CG18292" IPR017266:Cyclin-dependent kinase 2-associated protein 1/2 CG18292 11-Aug-17 DroID_v2017_08 Drer\cdk2ap2 - Cele\Y43F4B.10 "Xtro\cdk2ap2, Xtro\cdk2ap1" "Mmus\Cdk2ap1, Mmus\Cdk2ap2" "Hsap\CDK2AP1, Hsap\CDK2AP2" FBgn0002843 msc melanoscutellum http://flybase.org/reports/FBgn0002843 - gene - - - "ms, msc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive,body color defective" "scutellum,macrochaeta & adult thorax,scutellar bristle,eye,wing" FBgn0060334 l(3)S144812 lethal (3) S144812 http://flybase.org/reports/FBgn0060334 gene - - - "1448/12, l(3)S144812" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035495 CG14989 - http://flybase.org/reports/FBgn0035495 protein_coding_gene - - - "BcDNA:GH06302, CG14989" - CG14989 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC25585 K 0.225219301 0.252159666 -0.326452191 0.849593942 2.296285827 0.197026145 FBgn0035513 Cpr64Ad Cuticular protein 64Ad http://flybase.org/reports/FBgn0035513 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model lipid particle ; GO:0005811 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr64Ad, CG1259, DmelCpr64Ad" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG1259 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "partially lethal - majority die,some die during pupal stage" FBgn0067676 nain nain http://flybase.org/reports/FBgn0067676 gene molecular_function ; GO:0003674 | no biological data available oocyte growth ; GO:0001555 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available nain - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "oocyte,germline clone" FBgn0021902 l(2)k12402 lethal (2) k12402 http://flybase.org/reports/FBgn0021902 - gene - - - l(2)k12402 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027205 l(1)G0398 lethal (1) G0398 http://flybase.org/reports/FBgn0027205 - gene - - - l(1)G0398 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033961 ND-B15 NADH dehydrogenase (ubiquinone) B15 subunit http://flybase.org/reports/FBgn0033961 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR009866 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95168 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95168" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95168 mitochondrion ; GO:0005739 | inferred from direct assay "CG12859, anon-EST:fe3B12, CG 12859, NB5M, ND-B15" "IPR009866:NADH:ubiquinone oxidoreductase, subunit NDUFB4" CG12859 11-Aug-17 DroID_v2017_08 Drer\ndufb4 - Cele\nuo-6 - "Mmus\Gm3873, Mmus\Ndufb4" Hsap\NDUFB4 "lethal,visible" trichogen cell FBgn0046837 l(3)A4-4L7 lethal (3) A4-4L7 http://flybase.org/reports/FBgn0046837 gene - - - l(3)A4-4L7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037191 CG14448 - http://flybase.org/reports/FBgn0037191 protein_coding_gene - - - CG14448 - CG14448 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0024253 ami anosmic http://flybase.org/reports/FBgn0024253 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available ami - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0037069 Cpr78Cc Cuticular protein 78Cc http://flybase.org/reports/FBgn0037069 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "anon-EST:ParkEST167, BcDNA:RE32113, Cpr78Cc, CG7658, DmelCpr78Cc" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG7658 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0022026 l(2)k08914 lethal (2) k08914 http://flybase.org/reports/FBgn0022026 - gene - - - l(2)k08914 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266636 CR45143 - http://flybase.org/reports/FBgn0266636 non_protein_coding_gene - - - CR45143 - CR45143 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032955 CG2201 - http://flybase.org/reports/FBgn0032955 protein_coding_gene choline kinase activity ; GO:0004103 | non-traceable author statement ethanolamine kinase activity ; GO:0004305 | non-traceable author statement ethanolamine kinase activity ; GO:0004305 | inferred from sequence or structural similarity with SGD:S000004123 choline kinase activity ; GO:0004103 | inferred from sequence or structural similarity with SGD:S000004123 phosphorylation ; GO:0016310 | non-traceable author statement phosphatidylethanolamine biosynthetic process ; GO:0006646 | inferred from sequence or structural similarity with SGD:S000004123 phosphatidylcholine biosynthetic process ; GO:0006656 | inferred from sequence or structural similarity with SGD:S000004123 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000004123 CG2201 IPR011009:Protein kinase-like domain CG2201 11-Aug-17 DroID_v2017_08 "Drer\chka, Drer\chkb" "Scer\CKI1, Scer\EKI1" "Cele\ckb-2, Cele\ckb-1, Cele\cka-1, Cele\cka-2, Cele\ckc-1, Cele\ckb-3, Cele\ckb-4" "Xtro\chkb, Xtro\chka" "Mmus\Chkb, Mmus\Chka" "Hsap\CHKB, Hsap\CHKA" viable FBgn0060365 l(3)S138307 lethal (3) S138307 http://flybase.org/reports/FBgn0060365 gene - - - "1383/07, l(3)S138307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266910 CR45370 - http://flybase.org/reports/FBgn0266910 non_protein_coding_gene - - - CR45370 - CR45370 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266255 CR44950 - http://flybase.org/reports/FBgn0266255 non_protein_coding_gene - - - "CR44950, lincRNA.857" - CR44950 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020589 anon-57Ch anon-57Ch http://flybase.org/reports/FBgn0020589 - gene - - - anon-57Ch - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005009 dil(w[a]) dilutor of white-apricot http://flybase.org/reports/FBgn0005009 - gene - - - "dil-w[a], dil(w[a])" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0036154 CG6168 - http://flybase.org/reports/FBgn0036154 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from sequence model CG6168 IPR007484:Peptidase M28 CG6168 11-Aug-17 DroID_v2017_08 "Drer\qpctlb, Drer\qpct, Drer\qpctla" Scer\YFR018C Cele\H27A22.1 "Xtro\qpctl, Xtro\qpct" "Mmus\Qpct, Mmus\Qpctl" "Hsap\QPCT, Hsap\QPCTL" viable FBgn0005425 l(1)adl14 lethal (1) adl14 http://flybase.org/reports/FBgn0005425 - gene - - - "l(1)adl-14, l(1)adl14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,short lived" FBgn0264513 CR43912 - http://flybase.org/reports/FBgn0264513 non_protein_coding_gene - - - "CR43912, lincRNA.538, lincRNA.539" - CR43912 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039600 CG1646 - http://flybase.org/reports/FBgn0039600 protein_coding_gene pre-mRNA 5'-splice site binding ; GO:0030627 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000425278 "mRNA 5'-splice site recognition ; GO:0000395 | inferred from biological aspect of ancestor with PANTHER:PTN000425278 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004509 inferred from sequence or structural similarity with protein_id:BAA92024" U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000425278 U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity with SGD:S000004509 inferred from sequence or structural similarity with protein_id:BAA92024 commitment complex ; GO:0000243 | inferred from biological aspect of ancestor with PANTHER:PTN000425278 nucleus ; GO:0005634 | inferred by curator from GO:0000381 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000425278 "Prp39, CG1646" "IPR003107:HAT (Half-A-TPR) repeat, IPR011990:Tetratricopeptide-like helical domain" CG1646 11-Aug-17 DroID_v2017_08 "Drer\prpf39, Drer\si:ch211-114c17.1" "Scer\PRP39, Scer\PRP42" Cele\F25B4.5 "Xtro\prpf39.1, Xtro\prpf39.2" Mmus\Prpf39 Hsap\PRPF39 viable FBgn0013621 l(3)neo11 lethal (3) neo11 http://flybase.org/reports/FBgn0013621 - gene - - - l(3)neo11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016694 Pdp1 PAR-domain protein 1 http://flybase.org/reports/FBgn0016694 "FBgn0035820, FBgn0044667" protein_coding_gene "protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000945219 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype growth ; GO:0040007 | inferred from mutant phenotype regulation of lipid metabolic process ; GO:0019216 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay multicellular organism development ; GO:0007275 | inferred from biological aspect of ancestor with PANTHER:PTN000945219 response to nutrient ; GO:0007584 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from direct assay inferred from mutant phenotype inferred from genetic interaction with vri" nucleus ; GO:0005634 | inferred by curator from GO:0003700 nucleus ; GO:0005634 | inferred from direct assay "PAR-domain protein 1, Pdp1epsilon, pdp1, CG17888, PDP1, anon-WO0140519.206, Pdp1, PDP, PDP1epsilon, Pdp1 epsilon, pdp1epsilon, mel_pdp1, pdp, Pdp-1, Pdp1e, DM1, DM32, Pdp1&e;gr" "IPR004827:Basic-leucine zipper domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG17888 11-Aug-17 DroID_v2017_08 "Drer\nfil3-4, Drer\hlfa, Drer\dbpb, Drer\tefb, Drer\cebpb, Drer\ddit3, Drer\tefa, Drer\nfil3-2, Drer\hlfb, Drer\cebp1, Drer\si:dkey-172o19.2, Drer\nfil3-5, Drer\dbpa" - "Cele\ces-2, Cele\atf-2, Cele\zip-6, Cele\zip-7, Cele\atf-8" "Xtro\tef, Xtro\cebpb, Xtro\dbp, Xtro\hlf" "Mmus\Hlf, Mmus\Tef, Mmus\Cebpb, Mmus\Cebpe, Mmus\Dbp, Mmus\Cebpa" "Hsap\DBP, Hsap\HLF, Hsap\CEBPA, Hsap\TEF" "viable,fertile,circadian behavior defective,recessive,developmental rate defective,lethal,small body,mitotic cell cycle defective,cell non-autonomous,lethal - all die before end of larval stage,some die during larval stage" DRSC08897 K -1.676708196 -0.556742061 FBgn0022309 l(1)K84.3 lethal (1) K84.3 http://flybase.org/reports/FBgn0022309 - gene - - - l(1)K84.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030177 CG2972 - http://flybase.org/reports/FBgn0030177 protein_coding_gene endoribonuclease activity ; GO:0004521 | inferred from biological aspect of ancestor with PANTHER:PTN001766042 cellular response to starvation ; GO:0009267 | inferred from expression pattern maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN001766042 cleavage involved in rRNA processing ; GO:0000469 | inferred from biological aspect of ancestor with PANTHER:PTN001766042 neurogenesis ; GO:0022008 | inferred from mutant phenotype "preribosome, small subunit precursor ; GO:0030688 | inferred from biological aspect of ancestor with PANTHER:PTN001766042" CG2972 "IPR014881:Nin one binding (NOB1) Zn-ribbon-like, IPR017117:Ribonuclease Nob1, eukaryote, IPR029060:PIN domain-like, IPR033411:Ribonuclease, PIN domain" CG2972 11-Aug-17 DroID_v2017_08 Drer\nob1 Scer\NOB1 Cele\Y54E10BR.4 Xtro\nob1 Mmus\Nob1 Hsap\NOB1 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0039042 CG13837 - http://flybase.org/reports/FBgn0039042 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG13837 IPR002557:Chitin binding domain CG13837 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\cbd-1, Cele\W03F11.1" - - - viable FBgn0083041 snoRNA:Psi18S-1854b snoRNA:Psi18S-1854b http://flybase.org/reports/FBgn0083041 snoRNA_gene - - - "snoRNA:Psi18S-1854b, Psi18S-1854b, psi18S-1854b, CR34600, chrX:16979518..16979650" - CR34600 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000701 fltG flight defective G http://flybase.org/reports/FBgn0000701 - gene - - - fltG - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0031194 CG17598 - http://flybase.org/reports/FBgn0031194 protein_coding_gene cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR000222 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from electronic annotation with InterPro:IPR015655 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with HGNC:18583 protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR015655 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:18583 protein dephosphorylation ; GO:0006470 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:18583 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:18583 "PP2C, CG17598" "IPR000222:PPM-type phosphatase, divalent cation binding, IPR001932:PPM-type phosphatase domain, IPR015655:Protein phosphatase 2C family" CG17598 11-Aug-17 DroID_v2017_08 "Drer\ppm1j, Drer\ppm1h" - "Cele\tap-1, Cele\C42C1.2" "Xtro\ppm1j, Xtro\ppm1h" "Mmus\Ppm1h, Mmus\Ppm1m, Mmus\Ppm1j" "Hsap\PPM1H, Hsap\PPM1M, Hsap\PPM1J" viable DRSC20636 K -0.11600613 -0.720911304 -0.241919384 -0.403741787 1.70573182 -0.339971052 FBgn0038708 CG6255 - http://flybase.org/reports/FBgn0038708 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR005810, InterPro:IPR005811 cofactor binding ; GO:0048037 | inferred from electronic annotation with InterPro:IPR003781" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR005810, InterPro:IPR005811 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" - "AAF55672, anon-WO0140519.197, CG6255" "IPR003781:CoA-binding, IPR005810:Succinyl-CoA ligase, alpha subunit, IPR005811:ATP-citrate lyase/succinyl-CoA ligase, IPR016040:NAD(P)-binding domain, IPR016102:Succinyl-CoA synthetase-like, IPR017440:ATP-citrate lyase/succinyl-CoA ligase, active site, IPR033847:ATP-citrate lyase/succinyl-CoA ligase, conserved site" CG6255 11-Aug-17 DroID_v2017_08 Drer\suclg1 Scer\LSC1 "Cele\sucl-1, Cele\sucl-2" Xtro\suclg1 Mmus\Suclg1 Hsap\SUCLG1 "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0266599 Hsc70-4 Heat shock protein cognate 4 http://flybase.org/reports/FBgn0266599 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P38646 chaperone binding ; GO:0051087 | inferred from direct assay "heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P38646 nervous system development ; GO:0007399 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype inferred from genetic interaction with Csp inferred from physical interaction with Csp ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype late endosomal microautophagy ; GO:0061738 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay RNA interference ; GO:0016246 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype membrane organization ; GO:0061024 | inferred from direct assay axonal fasciculation ; GO:0007413 | inferred from mutant phenotype cellular response to topologically incorrect protein ; GO:0035967 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay perichromatin fibrils ; GO:0005726 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P38646 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | colocalizes_with inferred from direct assay Z disc ; GO:0030018 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG4264, mtHsp 70, HSC70-4, Hsc70-4, hsc70-4, Hsc4, HSC4, Q3KN45_DROME, Hsc70, BAP74, hsc4, i190, HSC-70, HSC70, hsc70, bs17d06.y1, E(nd)195, Hsc4p, E(csp)1545, scd, dhsc70, l(3)L3929, l(3)j7A4, l(3)03550, anon-WO0118547.237, Hsc-4, hsp70, Hsp70, Hsp-c4, Bap74, Hsc-70-4, chr3R:11070155..11070315, dHsp70, dHSP70, HSP70" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG4264 11-Aug-17 DroID_v2017_08 "Drer\hspa8, Drer\si:ch211-199o1.2, Drer\hspa12b, Drer\si:dkey-4p15.3, Drer\hspa13, Drer\hsp70.1, Drer\hspa14, Drer\hspa12a, Drer\hsp70.2, Drer\hspa5, Drer\nckap1, Drer\hsc70, Drer\hsp70l" "Scer\SSB2, Scer\SSA4, Scer\SSA2, Scer\KAR2, Scer\SSB1, Scer\SSA3, Scer\SSZ1, Scer\SSA1" "Cele\hsp-4, Cele\F11F1.1, Cele\hsp-1, Cele\F44E5.4, Cele\gex-3, Cele\F44E5.5, Cele\hsp-70, Cele\hsp-3" "Xtro\hspa12b, Xtro\hspa14, Xtro\hspa5, Xtro\hspa8, Xtro\hsp70, Xtro\nckap1l, Xtro\hspa13, Xtro\hspa1l, Xtro\hspa2, Xtro\hspa1b, Xtro\hspa1a, Xtro\nckap1" "Mmus\Hspa12b, Mmus\Hspa1b, Mmus\Nckap1l, Mmus\Hspa14, Mmus\Hspa1a, Mmus\Nckap1, Mmus\Hspa13, Mmus\Hspa5, Mmus\Hspa12a, Mmus\Hspa8, Mmus\Hspa2, Mmus\Hspa1l" "Hsap\HSPA2, Hsap\HSPA1B, Hsap\HSPA1A, Hsap\HSPA12B, Hsap\HSPA13, Hsap\NCKAP1, Hsap\HSPA1L, Hsap\NCKAP1L, Hsap\HSPA6, Hsap\HSPA12A, Hsap\HSPA5, Hsap\HSPA14, Hsap\HSPA8" DRSC16711 E 0.296934844 -0.719750652 -4.781154456 -1.760949267 1.133715354 0.518721172 FBgn0004918 spk spike http://flybase.org/reports/FBgn0004918 - gene - - - spk - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261631 CG42714 - http://flybase.org/reports/FBgn0261631 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42714, DMG8-chr3L.11.020" - CG42714 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002597 M(2)31A Minute (2) 31A http://flybase.org/reports/FBgn0002597 - gene - - - "M(2)e, M(2)30A, M(2)fs, M(2)LS3, M[[e]], M(2)t, M(2)S11, M(2)31A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible,developmental rate defective,female sterile" "macrochaeta,ovary,adult abdomen" FBgn0034255 Oxp Oxpecker http://flybase.org/reports/FBgn0034255 protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with Su(var)205 chromosome organization ; GO:0051276 | inferred from sequence or structural similarity with Su(var)205 chromatin ; GO:0000785 | inferred from sequence or structural similarity with Su(var)205 "Oxp, OXP, CG18186" "IPR017984:Chromo domain subgroup, IPR000953:Chromo/chromo shadow domain, IPR016197:Chromo domain-like, IPR023780:Chromo domain" CG18186 11-Aug-17 DroID_v2017_08 "Drer\cdyl, Drer\cbx3a, Drer\cbx1b, Drer\cbx1a, Drer\cbx3b" - "Cele\set-31, Cele\hpl-1" Xtro\cbx3 "Mmus\Cbx3, Mmus\Cdyl, Mmus\Mphosph8, Mmus\Cdyl2, Mmus\Cbx6" "Hsap\CDY1B, Hsap\CDY2A, Hsap\CBX3, Hsap\CDY1, Hsap\CDY2B, Hsap\CDYL, Hsap\MPHOSPH8, Hsap\CDYL2" viable FBgn0002594 M(2)24D Minute (2) 24D http://flybase.org/reports/FBgn0002594 - gene - - - "M(2)LS2, l(2)24Db, M(2)24D" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065946 l(2)SH0105 lethal (2) SH0105 http://flybase.org/reports/FBgn0065946 gene - - - "l(2)SH0105, l(2)SH2 0105" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062697 EP1154 EP1154 http://flybase.org/reports/FBgn0062697 gene - - - "EP(3)1154, EP1154" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005143 l(2)DTS1 lethal (2) DTS1 http://flybase.org/reports/FBgn0005143 - gene - - - l(2)DTS1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive" FBgn0016924 rope rope http://flybase.org/reports/FBgn0016924 - gene - - - rope - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052112 CG32112 - http://flybase.org/reports/FBgn0052112 protein_coding_gene - - - "CG10982, CG32112" "IPR019149:Abhydrolase domain containing 18, IPR029058:Alpha/Beta hydrolase fold" CG32112 11-Aug-17 DroID_v2017_08 Drer\abhd18 - Cele\C54G4.7 Xtro\abhd18 Mmus\Abhd18 Hsap\ABHD18 "viable,fertile" FBgn0036586 CG13070 - http://flybase.org/reports/FBgn0036586 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13070 - CG13070 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010595 l(2)05327b lethal (2) 05327b http://flybase.org/reports/FBgn0010595 - gene - - - "l(2)05327, l(2)05327b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0040052 CG17398 - http://flybase.org/reports/FBgn0040052 protein_coding_gene - - - CG17398 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037849 CG4596 - http://flybase.org/reports/FBgn0037849 protein_coding_gene - - - CG4596 IPR029386:TMEM169 protein CG4596 11-Aug-17 DroID_v2017_08 Drer\tmem169a - - Xtro\tmem169 Mmus\Tmem169 Hsap\TMEM169 viable FBgn0030309 CG1572 - http://flybase.org/reports/FBgn0030309 protein_coding_gene - positive regulation of hemocyte proliferation ; GO:0035208 | inferred from genetic interaction with hop integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001103553 CG1572 IPR008253:Marvel domain CG1572 11-Aug-17 DroID_v2017_08 "Drer\cmtm4, Drer\zgc:136605, Drer\cmtm6, Drer\cmtm3, Drer\cmtm7, Drer\plp2" - "Cele\K09G1.1, Cele\drr-1" - "Mmus\Cmtm7, Mmus\Cmtm2a, Mmus\Cmtm2b, Mmus\Cklf, Mmus\Cmtm1, Mmus\Cmtm5, Mmus\Plp2, Mmus\Cmtm3, Mmus\Cmtm6, Mmus\Cmtm4" "Hsap\CMTM4, Hsap\CMTM1, Hsap\CMTM2, Hsap\CMTM3, Hsap\CMTM6, Hsap\CKLF, Hsap\CMTM7, Hsap\PLP2, Hsap\CMTM5" viable FBgn0000765 fs(1)A1001 female sterile (1) A1001 http://flybase.org/reports/FBgn0000765 - gene - - - "fs(1)1001, fs(1)A1001" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile soma-dependent,recessive" FBgn0067658 sd-1 sd-1 http://flybase.org/reports/FBgn0067658 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,neurophysiology defective,somatic clone,phototaxis defective,lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0035192 CG9194 - http://flybase.org/reports/FBgn0035192 protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "lateral inhibition ; GO:0046331 | inferred from mutant phenotype potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" "anon-WO0109301.38, anon-WO0109301.37, anon-WO0109301.36, anon-WO0109301.34, anon-WO0109301.33, anon-WO0109301.32, anon-WO0109301.31, anon-WO0109301.29, anon-WO0109301.28, anon-WO0109301.27, anon-WO0109301.26, anon-WO0109301.25, anon-WO0109301.24, anon-WO0109301.23, anon-WO0109301.22, anon-WO0109301.21, anon-WO0109301.20, anon-WO0109301.19, anon-WO0109301.3, CG9194, C9194" "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG9194 11-Aug-17 DroID_v2017_08 "Drer\kcnk5a, Drer\kcnk1a, Drer\kcnk10a, Drer\kcnk6, Drer\kcnk1b, Drer\kcnk18, Drer\kcnk5b, Drer\kcnk10b, Drer\kcnk2a, Drer\kcnk7" Scer\TOK1 "Cele\twk-24, Cele\twk-28, Cele\twk-39, Cele\sup-9, Cele\twk-7, Cele\twk-48" "Xtro\kcnk5, Xtro\kcnk6, Xtro\kcnk18, Xtro\kcnk10, Xtro\kcnk7, Xtro\kcnk16, Xtro\LOC100486031, Xtro\kcnk2, Xtro\kcnk4, Xtro\kcnk1" "Mmus\Kcnk16, Mmus\Kcnk5, Mmus\Kcnk1, Mmus\Kcnk6, Mmus\Kcnk4, Mmus\Kcnk9, Mmus\Kcnk10, Mmus\Kcnk7, Mmus\Kcnk18, Mmus\Kcnk2" "Hsap\KCNK9, Hsap\KCNK7, Hsap\KCNK1, Hsap\KCNK18, Hsap\KCNK10, Hsap\KCNK16, Hsap\KCNK6, Hsap\KCNK17, Hsap\KCNK4, Hsap\KCNK5, Hsap\KCNK2" "visible,partially lethal - majority die,some die during pupal stage,viable" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0051934 CG31934 - http://flybase.org/reports/FBgn0051934 protein_coding_gene - - - CG31934 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031021 ND-18 NADH dehydrogenase (ubiquinone) 18 kDa subunit http://flybase.org/reports/FBgn0031021 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from sequence or structural similarity with UniProtKB:O43181 electron transport chain ; GO:0022900 | inferred from electronic annotation with InterPro:IPR006885 mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from sequence or structural similarity with HGNC:7711 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000259406 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O43181 "CG12203, IP11020p, NUYM, ND-18" "IPR006885:NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial" CG12203 11-Aug-17 DroID_v2017_08 Drer\ndufs4 - Cele\lpd-5 Xtro\ndufs4 Mmus\Ndufs4 Hsap\NDUFS4 "viable,visible" trichogen cell FBgn0033651 Ir48c Ionotropic receptor 48c http://flybase.org/reports/FBgn0033651 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model Golgi organization ; GO:0007030 | inferred from mutant phenotype detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a protein secretion ; GO:0009306 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG12444, TANGO3, Ir48c, DmelIR48c, IR48c, Tango3" - CG12444 11-Aug-17 DroID_v2017_08 - - Cele\glr-7 - - - viable DRSC06154 IE 0.159248029 1.596882124 2.137769543 -1.341743998 -0.095900073 0.971379028 FBgn0262818 CG43189 - http://flybase.org/reports/FBgn0262818 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43189 - CG43189 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259393 EP-730 - http://flybase.org/reports/FBgn0259393 gene - - - EP-730 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing" FBgn0264845 Tep5 Thioester-containing protein 5 http://flybase.org/reports/FBgn0264845 protein_coding_gene endopeptidase inhibitor activity ; GO:0004866 | inferred from electronic annotation with InterPro:IPR001599 - extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR011626 "Tep5, CG13079, TEP5mel, CG13080, dTEPV, TepV" "IPR013783:Immunoglobulin-like fold, IPR001599:Alpha-2-macroglobulin, IPR011626:Alpha-macroglobulin complement component, IPR009048:Alpha-macroglobulin, receptor-binding, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid" CG13079 11-Aug-17 DroID_v2017_08 "Drer\cpamd8, Drer\c3a.4, Drer\sb:cb37, Drer\c3b.1, Drer\c4, Drer\zgc:171426, Drer\a2ml, Drer\zgc:165453, Drer\c3a.2, Drer\c3b.2, Drer\cd109, Drer\zgc:165518, Drer\zgc:171445, Drer\LOC103909927, Drer\c3a.6, Drer\c5, Drer\si:dkey-105h12.2, Drer\si:ch211-212c13.10, Drer\si:dkey-46g23.5, Drer\si:dkey-8k3.2, Drer\si:dkey-46g23.2, Drer\c3a.3" - "Cele\F13D2.1, Cele\tep-1" "Xtro\a2ml1, Xtro\c3, Xtro\c5, Xtro\ovos2, Xtro\c4a" "Mmus\Pzp, Mmus\A2m, Mmus\BC048546, Mmus\AI182371, Mmus\Hc, Mmus\Cd109, Mmus\C3, Mmus\Mug2, Mmus\Mug1, Mmus\C4b" "Hsap\A2ML1, Hsap\OVOS, Hsap\A2M, Hsap\C4B, Hsap\C5, Hsap\C3, Hsap\PZP, Hsap\C4A, Hsap\CD109, Hsap\OVOS2" FBgn0035587 Gdap1 Gdap1 http://flybase.org/reports/FBgn0035587 protein_coding_gene - mitochondrial fission ; GO:0000266 | inferred from sequence or structural similarity with HGNC:15968 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:15968 "Gdap1, CG4623, GDAP1" "IPR004045:Glutathione S-transferase, N-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG4623 11-Aug-17 DroID_v2017_08 "Drer\gdap1, Drer\gdap1l1, Drer\eef1g" "Scer\TEF4, Scer\CAM1, Scer\GTT2, Scer\YGR201C" Cele\eef-1G "Xtro\gdap1, Xtro\gdap1l1" "Mmus\Gstt2, Mmus\Eef1g, Mmus\Gdap1l1, Mmus\Gdap1" "Hsap\GDAP1L1, Hsap\GDAP1, Hsap\GSTT2, Hsap\EEF1G" viable FBgn0060842 l(3)S049405b lethal (3) S049405b http://flybase.org/reports/FBgn0060842 gene - - - "0494/05, l(3)S049405b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028248 l(3)94Ba lethal (3) 94Ba http://flybase.org/reports/FBgn0028248 gene - - - l(3)94Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086545 MRE13 mRNA-like ncRNA in embryogenesis 13 http://flybase.org/reports/FBgn0086545 non_protein_coding_gene - - - "MRE13, GM09828" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011120 l(1)Q81 lethal (1) Q81 http://flybase.org/reports/FBgn0011120 FBgn0010210 gene - - - l(1)Q81 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267798 CR46123 - http://flybase.org/reports/FBgn0267798 non_protein_coding_gene - - - CR46123 - CR46123 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265148 CR44217 - http://flybase.org/reports/FBgn0265148 non_protein_coding_gene - - - "CR44217, lincRNA.223" - CR44217 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267449 WDY WD40 Y http://flybase.org/reports/FBgn0267449 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "WDY, CG40449, CG40245, CG40583, CG40551, CG41020, CG45799" "IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR019775:WD40 repeat, conserved site, IPR011992:EF-hand domain pair, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG45799 11-Aug-17 DroID_v2017_08 Drer\wdr95 "Scer\UTP4, Scer\MET30, Scer\RPN14, Scer\PAC1" - "Xtro\wdr49, Xtro\efcab8" "Mmus\Wdr64, Mmus\Wdr95, Mmus\Wdr49" "Hsap\WDR49, Hsap\EFCAB8, Hsap\WDR64" FBgn0262266 mir-980 mir-980 stem loop http://flybase.org/reports/FBgn0262266 miRNA_gene - memory ; GO:0007613 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype - "miR-980, mir-980, 980, CR42973, dme-miR-980, miR980" - CR42973 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing,wing vein,ectopic,wing vein L4,wing margin,wing blade,2nd posterior cell" FBgn0031615 CG11933 - http://flybase.org/reports/FBgn0031615 protein_coding_gene - - - "CT35796, CG11933" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065587 l(2)SH0909 lethal (2) SH0909 http://flybase.org/reports/FBgn0065587 gene - - - "l(2)SH0909, l(2)SH2 0909" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266980 CR45431 - http://flybase.org/reports/FBgn0266980 non_protein_coding_gene - - - CR45431 - CR45431 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267047 CG45491 - http://flybase.org/reports/FBgn0267047 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45491 - CG45491 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040873 CG12696 - http://flybase.org/reports/FBgn0040873 protein_coding_gene - - - CG12696 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011382 l(3)j5C7 lethal (3) j5C7 http://flybase.org/reports/FBgn0011382 - gene - - - l(3)j5C7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005458 l(1)v455 lethal (1) v455 http://flybase.org/reports/FBgn0005458 - gene - - - "l(1)455, l(1)v455" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041128 l(2)45Ah lethal (2) 45Ah http://flybase.org/reports/FBgn0041128 gene - - - l(2)45Ah - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" FBgn0260480 CG32295 - http://flybase.org/reports/FBgn0260480 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG16757, NEST:bs09a12, BEST:GH20547, CG32295" IPR027831:Domain of unknown function DUF4485 CG32295 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036091 CG18628 - http://flybase.org/reports/FBgn0036091 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "BcDNA:GH08251, CG18628" - CG18628 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060588 l(3)S093705b lethal (3) S093705b http://flybase.org/reports/FBgn0060588 gene - - - "0937/05, l(3)S093705b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262117 IntS3 Integrator 3 http://flybase.org/reports/FBgn0262117 protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:26153 Golgi apparatus ; GO:0005794 | inferred from direct assay integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:26153 "CG17665, IntS3, NC19, l(2)NC19, NC28, l(2)NC28, IR23, l(2Rh)IR23, l(2)IR23, Int3" IPR019333:Integrator complex subunit 3 CG17665 11-Aug-17 DroID_v2017_08 "Drer\gucy2g, Drer\si:dkey-37g12.1, Drer\ints3, Drer\npr2, Drer\npr1b, Drer\npr1a" - "Cele\gcy-1, Cele\gcy-28, Cele\gcy-4, Cele\gcy-22, Cele\gcy-13, Cele\gcy-12, Cele\gcy-7, Cele\gcy-2, Cele\Y92H12A.4, Cele\gcy-19, Cele\gcy-6, Cele\gcy-3, Cele\gcy-5, Cele\gcy-14, Cele\gcy-21, Cele\gcy-17" Xtro\npr1 "Mmus\Npr2, Mmus\Npr1, Mmus\Gucy2g, Mmus\Ints3" "Hsap\INTS3, Hsap\NPR1, Hsap\NPR2" DRSC21215 I 1.991568184 0.648212648 0.772768913 -0.565764732 0.779632106 1.004574303 FBgn0053541 CG33541 - http://flybase.org/reports/FBgn0053541 protein_coding_gene - - - "HDC14318, CG33541" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045476 Gr64e Gustatory receptor 64e http://flybase.org/reports/FBgn0045476 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype "detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from electronic annotation with InterPro:IPR009318 sensory perception of sweet taste ; GO:0050916 | inferred from genetic interaction with Gr64d, Gr64c, Gr64b, Gr64a, Gr64f sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009318 "DmGr64e, CG14988, Gr64A2, CG33157, CG32258, Gr64e, Dmel64e, Gr64, GR64e, gr64e" IPR009318:Gustatory receptor CG32258 11-Aug-17 DroID_v2017_08 - - - - - - "feeding behavior defective,taste perception defective" FBgn0044060 GTD74-236 GTD74-236 http://flybase.org/reports/FBgn0044060 gene - - - GTD74-236 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032602 ppk17 pickpocket 17 http://flybase.org/reports/FBgn0032602 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG13278, ppk17" IPR001873:Epithelial sodium channel CG13278 11-Aug-17 DroID_v2017_08 - - - - - "Hsap\ASIC2, Hsap\ASIC3" viable FBgn0028572 qtc quick-to-court http://flybase.org/reports/FBgn0028572 protein_coding_gene - "protein targeting to Golgi ; GO:0000042 | inferred from electronic annotation with InterPro:IPR000237 courtship behavior ; GO:0007619 | traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype mating behavior, sex discrimination ; GO:0048047 | inferred from direct assay" - "CG14039, qtc" IPR000237:GRIP domain CG14039 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage | male , adult stage , adult stage | female " " adult head

, antennal segment 3

, testis

, retina

, optic lobe

, antennal segment 2

, central nervous system &&of adult head

, subesophageal ganglion

, adult brain cortex

, antenna

, ejaculatory bulb

, maxillary palpus

, olfactory sensory organ

, female reproductive system | restricted

" "viable,fertile,courtship behavior defective,male,visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0067349 l(3)95Ec lethal (3) 95Ec http://flybase.org/reports/FBgn0067349 gene - - - l(3)95Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "wing margin,somatic clone,macrochaeta,eye,wing vein,embryo" FBgn0266057 Su(var)212 - http://flybase.org/reports/FBgn0266057 gene - - - "Su(var)212, 212" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0065157 l(3)SH048 lethal (3) SH048 http://flybase.org/reports/FBgn0065157 gene - - - "l(3)SH048, l(2)SH3 048" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053230 CG33230 - http://flybase.org/reports/FBgn0053230 protein_coding_gene protein-lysine N-methyltransferase activity ; GO:0016279 | inferred from biological aspect of ancestor with PANTHER:PTN000327874 ribosome biogenesis ; GO:0042254 | inferred from biological aspect of ancestor with PANTHER:PTN000327876 peptidyl-lysine monomethylation ; GO:0018026 | inferred from biological aspect of ancestor with PANTHER:PTN000327874 peptidyl-lysine trimethylation ; GO:0018023 | inferred from biological aspect of ancestor with PANTHER:PTN000327876 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000327876 CG33230 - CG33230 11-Aug-17 DroID_v2017_08 "Drer\setd6, Drer\setd4, Drer\setd3" "Scer\CTM1, Scer\RKM4, Scer\RKM2, Scer\EFM1, Scer\RKM3, Scer\RKM1" "Cele\set-29, Cele\set-27" "Xtro\setd6, Xtro\setd3, Xtro\setd4" "Mmus\Setd4, Mmus\Setd6, Mmus\Setd3" "Hsap\SETD6, Hsap\SETD3, Hsap\SETD4" "viable,visible" trichogen cell FBgn0029937 CG8300 - http://flybase.org/reports/FBgn0029937 protein_coding_gene - - - CG8300 IPR028260:FAM177 family CG8300 11-Aug-17 DroID_v2017_08 "Drer\fam177b, Drer\zgc:153383, Drer\fam177a1" - - Xtro\galnt11 "Mmus\Fam177a, Mmus\1700047I17Rik2" "Hsap\FAM177B, Hsap\FAM177A1" viable FBgn0024889 Kap-alpha1 karyopherin alpha1 http://flybase.org/reports/FBgn0024889 FBgn0062126 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 spermatogenesis ; GO:0007283 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 "imp alpha1, Kap alpha1, Kap-alpha1, CG8548, anon-WO0118547.276, IMPalpha1, Kpna1, Imp-alpha1, Dalpha1, Dmalpha1, impalpha1, Kapalpha1S1, alphaKap1, imp-alpha1" "IPR000225:Armadillo, IPR002652:Importin-alpha, importin-beta-binding domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024931:Importin subunit alpha, IPR032413:Atypical Arm repeat" CG8548 11-Aug-17 DroID_v2017_08 "Drer\kpna3, Drer\kpna1, Drer\spag6, Drer\kpna7, Drer\kpna4, Drer\kpna5, Drer\kpna6" Scer\SRP1 "Cele\ima-1, Cele\ima-3" "Xtro\kpna4, Xtro\armc3, Xtro\spag6, Xtro\kpna6, Xtro\kpna3, Xtro\kpna2, Xtro\kpna1, Xtro\kpna7" "Mmus\Kpna2, Mmus\Spag6, Mmus\Kpna3, Mmus\Kpna1, Mmus\Kpna4, Mmus\Kpna7, Mmus\Spag6l, Mmus\Kpna6" "Hsap\KPNA1, Hsap\KPNA4, Hsap\KPNA6, Hsap\KPNA2, Hsap\KPNA5, Hsap\SPAG6, Hsap\KPNA3, Hsap\KPNA7" "male sterile,lethal,heat sensitive,viable" tergite FBgn0060790 l(3)SzB90Cm lethal (3) SzB90Cm http://flybase.org/reports/FBgn0060790 gene - - - "0592/13, l(3)S059213b, l(3)SzB90Cm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0069341 TAHRE\pol TAHRE element pol http://flybase.org/reports/FBgn0069341 transposable_element_gene - - - "TAHRE\pol, ORF2" "IPR005135:Endonuclease/exonuclease/phosphatase, IPR000477:Reverse transcriptase domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028231 l(3)S004021 lethal (3) S004021 http://flybase.org/reports/FBgn0028231 gene - - - "0040/21, l(3)S004021" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044075 E(rst)I19 E(rst)I19 http://flybase.org/reports/FBgn0044075 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "I19, E(rst)I19" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027526 Ublcp1 Ubiquitin-like domain-containing C-terminal domain phosphatase 1 http://flybase.org/reports/FBgn0027526 - protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with HGNC:28110 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from biological aspect of ancestor with PANTHER:PTN001279492 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:28110 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:28110 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001279492 "CG6697, BcDNA:LD21504, UBLCP1, DmUBLCP1, Ublcp1, 4972728" "IPR000626:Ubiquitin domain, IPR004274:FCP1 homology domain, IPR011943:HAD-superfamily hydrolase, subfamily IIID, IPR029071:Ubiquitin-related domain, IPR023214:HAD-like domain" CG6697 11-Aug-17 DroID_v2017_08 "Drer\ctdspl3, Drer\ctdsplb, Drer\ublcp1, Drer\ctdsp2, Drer\ctdnep1a, Drer\ctdspl2a, Drer\usp14, Drer\ubfd1, Drer\ctdnep1b, Drer\ctdspla, Drer\ctdspl2b, Drer\ctdsp1, Drer\LOC103910001" "Scer\UBP6, Scer\PSR1, Scer\PSR2, Scer\NEM1" - "Xtro\ctdnep1, Xtro\ctdspl2, Xtro\ctdsp1, Xtro\ctdsp2, Xtro\usp14, Xtro\ctdspl, Xtro\ublcp1" "Mmus\Ctdspl2, Mmus\Ctdnep1, Mmus\Ublcp1, Mmus\Usp14, Mmus\Ctdsp2, Mmus\Ubfd1, Mmus\Ctdsp1, Mmus\Ctdspl" "Hsap\CTDSPL2, Hsap\USP14, Hsap\CTDSP1, Hsap\CTDSPL, Hsap\UBLCP1, Hsap\CTDNEP1, Hsap\UBFD1, Hsap\CTDSP2" viable FBgn0037435 CG18048 - http://flybase.org/reports/FBgn0037435 protein_coding_gene tRNA methyltransferase activity ; GO:0008175 | inferred from biological aspect of ancestor with PANTHER:PTN000313293 tRNA methylation ; GO:0030488 | inferred from biological aspect of ancestor with PANTHER:PTN000313293 - CG18048 "IPR021721:Zinc finger, CCCH-type, TRM13, IPR007871:Methyltransferase TRM13, IPR022776:TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG18048 11-Aug-17 DroID_v2017_08 Drer\trmt13 Scer\TRM13 Cele\Y49A3A.3 Xtro\trmt13 Mmus\Trmt13 Hsap\TRMT13 viable FBgn0027265 l(1)G0220 lethal (1) G0220 http://flybase.org/reports/FBgn0027265 - gene - - - l(1)G0220 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,male,female" FBgn0265096 CR44201 - http://flybase.org/reports/FBgn0265096 non_protein_coding_gene - - - CR44201 - CR44201 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267544 CR45884 - http://flybase.org/reports/FBgn0267544 non_protein_coding_gene - - - CR45884 - CR45884 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260370 GSd309 - http://flybase.org/reports/FBgn0260370 gene - - - GSd309 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065702 l(2)SH0620 lethal (2) SH0620 http://flybase.org/reports/FBgn0065702 gene - - - "l(2)SH0620, l(2)SH2 0620" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011409 l(3)j8B6 lethal (3) j8B6 http://flybase.org/reports/FBgn0011409 - gene - - - l(3)j8B6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044441 HMS-Beagle\pol HMS-Beagle element pol http://flybase.org/reports/FBgn0044441 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "midline-jumper\pol, midline-element\pol, HMS-Beagle\pol" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011029 l(3)s2521 lethal (3) s2521 http://flybase.org/reports/FBgn0011029 - gene - - - l(3)s2521 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084047 CG41516 - http://flybase.org/reports/FBgn0084047 protein_coding_gene - - - CG41516 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052311 zormin zormin http://flybase.org/reports/FBgn0052311 protein_coding_gene actin binding ; GO:0003779 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with rols - Z disc ; GO:0030018 | inferred from direct assay M band ; GO:0031430 | inferred from direct assay Z disc ; GO:0030018 | inferred from physical interaction with rols "CG5699, CT36990, CG32311, CG32310, CG32307, CG32309, CG11952, CG11953, CG1282, CG11850, CG33484, BcDNA:GH09541, zormin" "IPR003598:Immunoglobulin subtype 2, IPR002017:Spectrin repeat, IPR013098:Immunoglobulin I-set, IPR013783:Immunoglobulin-like fold, IPR018159:Spectrin/alpha-actinin, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype" CG33484 11-Aug-17 DroID_v2017_08 "Drer\leo1, Drer\palld, Drer\si:dkey-65j6.2, Drer\LOC569231, Drer\myot, Drer\triob, Drer\rp1, Drer\sestd1, Drer\trioa, Drer\spega, Drer\quo" Scer\YFR016C "Cele\sax-3, Cele\F21C10.7" "Xtro\sestd1, Xtro\myot, Xtro\leo1, Xtro\trio" "Mmus\Trio, Mmus\Mcf2, Mmus\Leo1, Mmus\Myot, Mmus\Palld, Mmus\Mypn, Mmus\Mylk, Mmus\Ibsp, Mmus\Dmp1, Mmus\Sestd1, Mmus\Rp1, Mmus\Kalrn" "Hsap\LEO1, Hsap\PLEKHG4B, Hsap\MYOT, Hsap\SESTD1, Hsap\RP1, Hsap\MCF2, Hsap\PALLD, Hsap\DMP1, Hsap\MYPN, Hsap\KALRN, Hsap\MYLK, Hsap\MCF2L2, Hsap\TRIO, Hsap\CCDC141, Hsap\IBSP" "viable,visible,planar polarity defective" "trichogen cell,mesothoracic tergum,chaeta,supernumerary" FBgn0051787 CG31787 - http://flybase.org/reports/FBgn0051787 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence model transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR009038 Golgi vesicle transport ; GO:0048193 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from sequence model "CG31787, p24" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG31787 11-Aug-17 DroID_v2017_08 "Drer\tmed1a, Drer\tmed1b, Drer\tmed3, Drer\tmed5, Drer\tmed7" "Scer\EMP24, Scer\ERP3, Scer\ERP4, Scer\ERP2" "Cele\K08E4.6, Cele\F57B10.5" "Xtro\tmed5, Xtro\tmed7, Xtro\tmed1" "Mmus\Tmed1, Mmus\Tmed7, Mmus\Tmed3, Mmus\Tmed5" "Hsap\TMED3, Hsap\TMED1, Hsap\TMED5, Hsap\TMED7, Hsap\TMED7-TICAM2, Hsap\TICAM2" viable DRSC01632 E -0.22589936 0.024686309 -1.510855192 -1.054397393 -0.307105363 0.295794255 FBgn0005505 l(2)24EFc lethal (2) 24EFc http://flybase.org/reports/FBgn0005505 - gene - - - "l(2)Gr.III, l(2)24EFc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029814 CG15765 - http://flybase.org/reports/FBgn0029814 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 transmembrane signaling receptor activity ; GO:0004888 | inferred from biological aspect of ancestor with PANTHER:PTN000177070 nervous system development ; GO:0007399 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177070 CG15765 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold, IPR015943:WD40/YVTN repeat-like-containing domain" CG15765 11-Aug-17 DroID_v2017_08 Drer\cd302 - "Cele\clec-51, Cele\clec-161, Cele\clec-53, Cele\clec-148, Cele\clec-180, Cele\clec-89, Cele\clec-162, Cele\clec-52" - - Hsap\LINC00083 "viable,fertile" FBgn0031497 SerRS Seryl-tRNA synthetase http://flybase.org/reports/FBgn0031497 protein_coding_gene serine-tRNA ligase activity ; GO:0004828 | inferred from electronic annotation with InterPro:IPR002317 ATP binding ; GO:0005524 | inferred from direct assay serine-tRNA ligase activity ; GO:0004828 | traceable author statement seryl-tRNA aminoacylation ; GO:0006434 | inferred from electronic annotation with InterPro:IPR002317 seryl-tRNA aminoacylation ; GO:0006434 | traceable author statement cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002317 cytoplasm ; GO:0005737 | traceable author statement "SerRS, DmSRS1, CG17259" "IPR002314:Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR002317:Serine-tRNA ligase, type1, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR010978:tRNA-binding arm, IPR015866:Serine-tRNA synthetase, type1, N-terminal, IPR033729:Serine-tRNA ligase catalytic core domain" CG17259 11-Aug-17 DroID_v2017_08 "Drer\sars2, Drer\sars" "Scer\SES1, Scer\DIA4" "Cele\sars-2, Cele\sars-1" "Xtro\sars2, Xtro\sars" "Mmus\Sars, Mmus\Sars2" "Hsap\SARS, Hsap\SARS2" lysosome & larval fat body | somatic clone | cell autonomous FBgn0002404 l(3)99De lethal (3) 99De http://flybase.org/reports/FBgn0002404 - gene - - - l(3)99De - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011778 l(2)DTS91 lethal (2) DTS91 http://flybase.org/reports/FBgn0011778 - gene - - - "DTS-91, DTS91, l(2)DTS91" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive" FBgn0020551 fs(2)35Ec fs(2)35Ec http://flybase.org/reports/FBgn0020551 - gene - - - fs(2)35Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050378 CG30378 - http://flybase.org/reports/FBgn0050378 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "NEST:bs08d04, CG30378, CBP6" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG30378 11-Aug-17 DroID_v2017_08 "Drer\pvalb1, Drer\cabp1b, Drer\calm1a, Drer\rhbdl3, Drer\pvalb3, Drer\calm2b, Drer\calm2a, Drer\scgn, Drer\calm3a, Drer\caln1, Drer\calml4a, Drer\calb1, Drer\calb2b, Drer\pvalb4, Drer\tnnc1a, Drer\pvalb8, Drer\cabp1a, Drer\si:ch211-197n1.2, Drer\pvalb9, Drer\cabp5a, Drer\tnnc2, Drer\cabp7b, Drer\calm3b, Drer\efcab6, Drer\calb2a, Drer\cabp5b, Drer\pvalb6, Drer\efcab2, Drer\calml4b, Drer\caln2, Drer\efcab11, Drer\calm1b, Drer\cabp2a, Drer\pvalb2, Drer\tnnc1b" "Scer\MLC2, Scer\MLC1, Scer\CMD1, Scer\CDC31" "Cele\H10E21.4, Cele\cal-3, Cele\cal-2, Cele\cal-5, Cele\cal-1, Cele\cal-4" "Xtro\tnnc2, Xtro\LOC548651, Xtro\pvalb.2, Xtro\calml4, Xtro\cabp7, Xtro\ocm.2, Xtro\pgm1, Xtro\calm2, Xtro\pvalb.1, Xtro\tnnc1, Xtro\calm1, Xtro\cabp4, Xtro\pvalb, Xtro\calb1, Xtro\scgn, Xtro\ocm, Xtro\efcab6" "Mmus\Cabp1, Mmus\Scgn, Mmus\1700023F06Rik, Mmus\Efcab9, Mmus\Spata21, Mmus\Cabp7, Mmus\Tnnc2, Mmus\Efcab7, Mmus\Ocm, Mmus\Efcab11, Mmus\Efcab2, Mmus\Rhbdl3, Mmus\Pvalb, Mmus\Efcab6, Mmus\Caln1, Mmus\Calm2, Mmus\Cabp2, Mmus\Calb2, Mmus\Calm1, Mmus\Efcab3, Mmus\Cabp4, Mmus\Calb1, Mmus\Tnnc1, Mmus\Calml4, Mmus\Calm4, Mmus\Calml3, Mmus\Calm3, Mmus\Cabp5" "Hsap\CABP1, Hsap\SCGN, Hsap\CALML5, Hsap\EFCAB3, Hsap\CALN1, Hsap\CALB1, Hsap\EFCAB2, Hsap\CALM2, Hsap\TNNC2, Hsap\EFCAB6, Hsap\CALM3, Hsap\CABP7, Hsap\CALML6, Hsap\CALM1, Hsap\SPATA21, Hsap\EFCAB13, Hsap\CALML4, Hsap\CALML3, Hsap\TNNC1, Hsap\EFCAB9, Hsap\PVALB, Hsap\EFCAB7, Hsap\CABP2, Hsap\CALB2, Hsap\OCM, Hsap\EFCAB11, Hsap\OCM2, Hsap\CABP5, Hsap\RHBDL3, Hsap\CABP4" viable FBgn0266036 CR44801 - http://flybase.org/reports/FBgn0266036 non_protein_coding_gene - - - "CR44801, lincRNA.6" - CR44801 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034805 CG13534 - http://flybase.org/reports/FBgn0034805 protein_coding_gene - - - CG13534 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260354 GSd201 - http://flybase.org/reports/FBgn0260354 gene - - - GSd201 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0001674 l(1)EN11 lethal (1) from Eugene Nonautonomous 11 http://flybase.org/reports/FBgn0001674 - gene - - - l(1)EN11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,melanotic mass phenotype" melanotic mass FBgn0000976 fs(2)HO103 female sterile (2) HO103 http://flybase.org/reports/FBgn0000976 - gene - - - "fs(2)103B, fs(2)HO103" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083241 EP2 EP2 http://flybase.org/reports/FBgn0083241 gene - - - EP2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264572 CR43944 - http://flybase.org/reports/FBgn0264572 non_protein_coding_gene - - - CR43944 - CR43944 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002275 l(3)70Ac lethal (3) 70Ac http://flybase.org/reports/FBgn0002275 - gene - - - "l(3)ZF3, l(3)70Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033713 CG8841 - http://flybase.org/reports/FBgn0033713 protein_coding_gene molecular_function ; GO:0003674 | no biological data available intracellular protein transport ; GO:0006886 | inferred from sequence or structural similarity with HGNC:15736 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000491103 Golgi medial cisterna ; GO:0005797 | inferred from biological aspect of ancestor with PANTHER:PTN000491103 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000491103 Golgi trans cisterna ; GO:0000138 | inferred from biological aspect of ancestor with PANTHER:PTN000491103 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:15736 "CG8841, Dmc1" IPR026705:Hid-1/Ecm30 CG8841 11-Aug-17 DroID_v2017_08 "Drer\hid1b, Drer\hid1a" Scer\ECM30 Cele\hid-1 Xtro\hid1 Mmus\Hid1 Hsap\HID1 viable FBgn0037544 CG11035 - http://flybase.org/reports/FBgn0037544 protein_coding_gene - - - "anon-WO0118547.426, CG11035" "IPR001623:DnaJ domain, IPR018253:DnaJ domain, conserved site" CG11035 11-Aug-17 DroID_v2017_08 "Drer\dnajc30, Drer\zgc:122979, Drer\dnajc30b" "Scer\JJJ2, Scer\APJ1, Scer\SCJ1, Scer\ERJ5, Scer\JJJ1, Scer\JJJ3" "Cele\dnj-18, Cele\dnj-4" - "Mmus\Dnajc30, Mmus\4930503B20Rik" Hsap\DNAJC30 viable FBgn0060708 l(3)S070316 lethal (3) S070316 http://flybase.org/reports/FBgn0060708 gene - - - "0703/16, l(3)S070316" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0065528 l(2)SH1114 lethal (2) SH1114 http://flybase.net/reports/FBgn0065528.html gene l(2)SH2 1114 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0029020 l(3)77CDd lethal (3) 77CDd http://flybase.org/reports/FBgn0029020 gene - - - l(3)77CDd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0085613 CG41322 - http://flybase.org/reports/FBgn0085613 protein_coding_gene - - - CG41322 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051821 CG31821 - http://flybase.org/reports/FBgn0051821 protein_coding_gene serine-type carboxypeptidase activity ; GO:0004185 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 serine-type carboxypeptidase activity ; GO:0004185 | inferred from sequence or structural similarity proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 - "BG:DS00365.3, CG7647, CG31821" "IPR001563:Peptidase S10, serine carboxypeptidase, IPR018202:Serine carboxypeptidase, serine active site, IPR029058:Alpha/Beta hydrolase fold" CG31821 11-Aug-17 DroID_v2017_08 Drer\scpep1 "Scer\YBR139W, Scer\KEX1" "Cele\Y32F6A.5, Cele\ctsa-1, Cele\C08H9.1, Cele\F41C3.5, Cele\F32A5.3, Cele\K10C2.1" Xtro\scpep1 "Mmus\Scpep1, Mmus\Ctsa" "Hsap\SCPEP1, Hsap\CTSA" "viable,visible" trichogen cell FBgn0262470 EP1318 - http://flybase.org/reports/FBgn0262470 gene - - - EP1318 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014049 Su(tor)2-278 Su(tor)2-278 http://flybase.org/reports/FBgn0014049 - gene - - - Su(tor)2-278 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0065201 l(2)SH2293 lethal (2) SH2293 http://flybase.org/reports/FBgn0065201 gene - - - "l(2)SH2293, l(2)SH2 2293" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013684 mt:ND5 mitochondrial NADH-ubiquinone oxidoreductase chain 5 http://flybase.org/reports/FBgn0013684 FBgn0002867 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR010934, InterPro:IPR018393" "ATP synthesis coupled electron transport ; GO:0042773 | inferred from electronic annotation with InterPro:IPR010934, InterPro:IPR018393" - "CG34083, ND5, NADH5, URF5, mt:ND5, nd5, nad5" "IPR018393:NADH-plastoquinone oxidoreductase, chain 5 subgroup, IPR001516:NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal, IPR001750:NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit, IPR010934:NADH dehydrogenase subunit 5, C-terminal" CG34083 11-Aug-17 DroID_v2017_08 Drer\ND5 - Cele\ND5 Xtro\ND5 Mmus\ND5 Hsap\ND5 FBgn0052831 CG33695 - http://flybase.org/reports/FBgn0052831 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 - MLL1 complex ; GO:0071339 | inferred from biological aspect of ancestor with PANTHER:PTN001086092 NURF complex ; GO:0016589 | inferred from biological aspect of ancestor with PANTHER:PTN001086092 "CG16917, CG32955, l(2)k07716, CG4831, CG32831, CG32955-ORFB, CG33695" IPR009057:Homeobox domain-like CG33695 11-Aug-17 DroID_v2017_08 "Drer\zgc:103508, Drer\zgc:92664" - Cele\Y43F8C.6 Xtro\c17orf49 Mmus\0610010K14Rik Hsap\C17orf49 DRSC01163 IE -1.874611492 -1.177843601 2.49473981 0.328624915 0.114850001 -0.329066544 FBgn0050462 ste24c ste24c prenyl protease type I http://flybase.org/reports/FBgn0050462 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000012712 spermatogenesis ; GO:0007283 | inferred from mutant phenotype CAAX-box protein processing ; GO:0071586 | inferred from biological aspect of ancestor with PANTHER:PTN000012712 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000012714 "CG33142, CG30462, CG9002, ste24c, Dmel\Ste24, Dmel\Ste24c" "IPR001915:Peptidase M48, IPR027057:CAAX prenyl protease 1, IPR032456:CAAX prenyl protease 1, N-terminal" CG9002 11-Aug-17 DroID_v2017_08 Drer\zmpste24 Scer\STE24 Cele\fce-1 Xtro\zmpste24 Mmus\Zmpste24 Hsap\ZMPSTE24 "viable,fertile" FBgn0030478 CG1640 - http://flybase.org/reports/FBgn0030478 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR015421, InterPro:IPR015422 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839" biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004839 cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CG1640, ALT, cg1640" "IPR004839:Aminotransferase, class I/classII, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase" CG1640 11-Aug-17 DroID_v2017_08 "Drer\gpt2l, Drer\sharpin, Drer\LOC101882185, Drer\gpt2, Drer\gpt, Drer\si:ch211-217a12.1" "Scer\ALT1, Scer\ALT2" "Cele\C32F10.8, Cele\T04F3.1" Xtro\gpt2 "Mmus\Gpt2, Mmus\Gpt" "Hsap\GPT2, Hsap\GPT" "viable,fertile,visible" trichogen cell FBgn0083288 E(smoDN)2070 Enhancer of smoDN 2070 http://flybase.org/reports/FBgn0083288 gene - - - E(smoDN)2070 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026646 l(2)k02405 lethal (2) k02405 http://flybase.org/reports/FBgn0026646 - gene - - - l(2)k02405 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010881 l(3)05967 lethal (3) 05967 http://flybase.org/reports/FBgn0010881 - gene - - - l(3)05967 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002212 l(3)67BDj lethal (3) 67BDj http://flybase.org/reports/FBgn0002212 - gene - - - "l(3)e80A6-2, l(3)67BDj" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044416 Scim11 Sensitized chromosome inheritance modifier 11 http://flybase.org/reports/FBgn0044416 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0265757 CR44564 - http://flybase.org/reports/FBgn0265757 non_protein_coding_gene - - - "CR44564, lincRNA.589" - CR44564 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069218 gl(3R)60-38 gl(3R)60-38 http://flybase.org/reports/FBgn0069218 gene molecular_function ; GO:0003674 | no biological data available anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(3R)60-38 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryo,germline clone,maternal effect,posterior" FBgn0033081 geminin geminin http://flybase.org/reports/FBgn0033081 protein_coding_gene - negative regulation of DNA replication ; GO:0008156 | inferred from direct assay negative regulation of DNA replication ; GO:0008156 | inferred from mutant phenotype negative regulation of DNA replication ; GO:0008156 | inferred from direct assay inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with brm endomitotic cell cycle ; GO:0007113 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | traceable author statement negative regulation of DNA replication ; GO:0008156 | traceable author statement regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Gem, CG3183, Dm Geminin, Dm geminin, v(2)k09107, l(2)k14019, anon-WO0257455.1, geminin, Geminin, gem" IPR022786:Geminin/Multicilin CG3183 11-Aug-17 DroID_v2017_08 "Drer\gmnc, Drer\gmnn" - - Xtro\gmnn "Mmus\Gmnc, Mmus\Mcidas, Mmus\Gmnn" "Hsap\GMNC, Hsap\MCIDAS, Hsap\GMNN" "lethal - all die before end of P-stage,some die during P-stage,lethal,recessive,visible,female sterile,partially,increased cell death,endomitotic cell cycle defective,mitotic cell cycle defective" "imaginal disc,follicle cell,cycle 16 embryo,mitotic cell cycleST1),mitotic anaphaseST1),anaphase & condensed nuclear chromosomeST1),embryonic/larval midgut primordium,embryonic hindgut,embryonic Malpighian tubule,presumptive embryonic/larval central nervous system,eye disc,eye,S phaseGMR.PF,ommatidium,S phaseen-e16E,mitotic M phaseen-e16E,embryonic/larval neuron,ectopic,presumptive embryonic/larval peripheral nervous system,peripheral nervous system,S phaseey.PH,lch5 neuron,wing disc | third instar larval stage" DRSC04984 K -0.284681822 -0.79704177 -0.04788526 -0.75284165 2.502252921 3.215856551 FBgn0041751 hocher hocher http://flybase.org/reports/FBgn0041751 gene - - - hocher - - 11-Aug-17 DroID_v2017_08 - - - - - - visible adult thorax FBgn0060750 l(3)S065104b lethal (3) S065104b http://flybase.org/reports/FBgn0060750 gene - - - "0651/04, l(3)S065104b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266952 CR45403 - http://flybase.org/reports/FBgn0266952 non_protein_coding_gene - - - CR45403 - CR45403 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010840 l(3)04449 lethal (3) 04449 http://flybase.org/reports/FBgn0010840 - gene - - - "86/14, 1295/10, 0708/15, 0086/14, l(3)04449" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025868 C8-3-37 C8-3-37 http://flybase.org/reports/FBgn0025868 - gene - - - C8-3-37 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0262608 CG43134 - http://flybase.org/reports/FBgn0262608 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43134 - CG43134 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267916 CR46197 - http://flybase.org/reports/FBgn0267916 non_protein_coding_gene - - - "CR46197, lincRNA.579" - CR46197 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035539 slow slowdown http://flybase.org/reports/FBgn0035539 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" synaptic target recognition ; GO:0008039 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype muscle tendon junction ; GO:0005927 | inferred from mutant phenotype "CT22877, slomo, CG7447, slow, Slow, blr" "IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR011489:EMI domain, IPR013032:EGF-like, conserved site, IPR018097:EGF-like calcium-binding, conserved site" CG7447 11-Aug-17 DroID_v2017_08 "Drer\LOC101884488, Drer\egfl7, Drer\npnt, Drer\tdgf1, Drer\egfl6, Drer\ccbe1" - "Cele\mec-9, Cele\egas-4" "Xtro\MGC89178, Xtro\egfl8, Xtro\egfl6, Xtro\egfl7" "Mmus\Cd93, Mmus\Tdgf1, Mmus\Cfc1, Mmus\Egfl7, Mmus\Egfl6, Mmus\Npnt, Mmus\Proz, Mmus\Egfl8" "Hsap\PROZ, Hsap\EGFL7, Hsap\CFC1, Hsap\TDGF1, Hsap\CFC1B, Hsap\NPNT, Hsap\EGFL6, Hsap\EGFL8" "partially lethal - majority live,locomotor rhythm defective,flight defective,size defective,viable" "embryonic/larval somatic muscle,muscle attachment site,wing,posterior" FBgn0035004 Pgam5-2 Phosphoglycerate mutase 5-2 http://flybase.org/reports/FBgn0035004 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with Pgam5 positive regulation of mitochondrial fission ; GO:0090141 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with Pgam5 cellular_component ; GO:0005575 | no biological data available "CG15874, Pgam5-2, dPGAM5-2" "IPR013078:Histidine phosphatase superfamily, clade-1, IPR029033:Histidine phosphatase superfamily" CG15874 11-Aug-17 DroID_v2017_08 Drer\pgam5 Scer\YOR283W Cele\pgam-5 Xtro\pgam5 Mmus\Pgam5 "Hsap\PGAM5, Hsap\PXMP2" "short lived,viable,fertile" mitochondrionda.G32 FBgn0034662 CG13492 - http://flybase.org/reports/FBgn0034662 protein_coding_gene - - - CG13492 IPR008472:Domain of unknown function DUF753 CG13492 11-Aug-17 DroID_v2017_08 - - "Cele\gfi-1, Cele\mup-4" Xtro\kcp - - viable FBgn0000168 bd balding http://flybase.org/reports/FBgn0000168 - gene - - - "bald, bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" acrostichal bristle FBgn0085707 CG41581 - http://flybase.org/reports/FBgn0085707 protein_coding_gene - - - CG41581 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035590 Prpk p53-related protein kinase http://flybase.org/reports/FBgn0035590 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR010440 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000258657 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:16197" positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:16197 positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype tRNA threonylcarbamoyladenosine metabolic process ; GO:0070525 | inferred from biological aspect of ancestor with PANTHER:PTN000258658 positive regulation of TOR signaling ; GO:0032008 | inferred from genetic interaction with S6k membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR010440 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000258658 EKC/KEOPS complex ; GO:0000408 | inferred from biological aspect of ancestor with PANTHER:PTN000258658 cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000258657 "Prpk, CG10673, Dm bud32" "IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR022495:Serine/threonine-protein kinase Bud32, IPR010440:Lipopolysaccharide kinase" CG10673 11-Aug-17 DroID_v2017_08 Drer\tp53rk "Scer\BUD32, Scer\STE11" Cele\F52C12.6 Xtro\tp53rk "Mmus\Trp53rkb, Mmus\Tex9, Mmus\Trp53rka" Hsap\TP53RK "visible,decreased cell size,small body,lethal,viable" "1st posterior cell,wing disc,somatic clone | third instar larval stage,embryonic/larval fat body" FBgn0069139 mcl(3)Z5578 mcl(3)Z5578 http://flybase.org/reports/FBgn0069139 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z5578 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0024630 l(2)k14403 lethal (2) k14403 http://flybase.org/reports/FBgn0024630 - gene - - - "144/3, l(2)k14403" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262180 mir-2283 mir-2283 stem loop http://flybase.org/reports/FBgn0262180 miRNA_gene - - - "mir-2283, CR42887, miR-2283, dme-mir-2283" - CR42887 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013734 spb split brain http://flybase.org/reports/FBgn0013734 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available spb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065408 l(2)SH1576 lethal (2) SH1576 http://flybase.org/reports/FBgn0065408 gene - - - "l(2)SH1576, l(2)SH2 1576" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019890 Smg5 Smg5 http://flybase.org/reports/FBgn0019890 FBgn0027901 protein_coding_gene telomerase RNA binding ; GO:0070034 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 telomeric DNA binding ; GO:0042162 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 ribonuclease activity ; GO:0004540 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 ribonucleoprotein complex binding ; GO:0043021 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 "mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 RNA interference ; GO:0016246 | NOT inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype regulation of RNA stability ; GO:0043487 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 gene silencing by miRNA ; GO:0035195 | NOT inferred from mutant phenotype telomere maintenance via telomerase ; GO:0007004 | inferred from biological aspect of ancestor with PANTHER:PTN000403280" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 telomerase holoenzyme complex ; GO:0005697 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 "CG8954, SMG5, anon-34Ea, BG:DS08220.2, Smg5, dSMG5, smg5" "IPR018834:DNA/RNA-binding domain, Est1-type, IPR019458:Telomerase activating protein Est1, IPR011990:Tetratricopeptide-like helical domain, IPR002716:PIN domain, IPR029060:PIN domain-like" CG8954 11-Aug-17 DroID_v2017_08 "Drer\smg7, Drer\smg5" "Scer\EST1, Scer\EBS1" Cele\smg-6 Xtro\smg7 "Mmus\Smg5, Mmus\Smg7" "Hsap\SMG5, Hsap\SMG7" "viable,neuroanatomy defective" "intersegmental nerve,anterior fascicle & synapse" DRSC03124 IE -0.924971499 -4.650349812 -1.236786519 -2.743007985 0.111009153 -0.350325352 FBgn0011157 l(1)Q235 lethal (1) Q235 http://flybase.org/reports/FBgn0011157 FBgn0010210 gene - - - l(1)Q235 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004773 l(3)91Cb lethal (3) 91Cb http://flybase.org/reports/FBgn0004773 - gene - - - "l(3)CR2, l(3)91Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0084237 2335 2335 http://flybase.org/reports/FBgn0084237 gene - - - 2335 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026219 l(3)05143 lethal (3) 05143 http://flybase.org/reports/FBgn0026219 - gene - - - l(3)05143 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024624 l(3)63Dc lethal (3) 63Dc http://flybase.org/reports/FBgn0024624 - gene - - - l(3)63Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037846 CG6574 - http://flybase.org/reports/FBgn0037846 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000841430 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000841430 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002666 CG6574 "IPR002666:Reduced folate carrier, IPR020846:Major facilitator superfamily domain" CG6574 11-Aug-17 DroID_v2017_08 "Drer\slc19a1, Drer\slc19a2, Drer\slc19a3b, Drer\slc19a3a" - "Cele\folt-2, Cele\folt-3, Cele\folt-1" "Xtro\slc19a2, Xtro\slc19a1" "Mmus\Slc19a2, Mmus\Slc19a3, Mmus\Slc19a1" "Hsap\C2orf83, Hsap\SLC19A3, Hsap\SLC19A1, Hsap\SLC19A2" "viable,fertile" DRSC16070 K -0.791634782 0.145794394 -0.082180911 0.179523725 -0.366187422 1.596677914 FBgn0267442 CR45792 - http://flybase.org/reports/FBgn0267442 non_protein_coding_gene - - - "CR45792, Mgn94021" - CR45792 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005375 x5 x5 http://flybase.org/reports/FBgn0005375 - gene - - - x5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005319 neu neuter http://flybase.org/reports/FBgn0005319 - gene - - - "neu, Neu" - - 11-Aug-17 DroID_v2017_08 - - - - - - "sex-determination defective,female,recessive,male fertile" FBgn0065664 l(2)SH0702 lethal (2) SH0702 http://flybase.org/reports/FBgn0065664 gene - - - "l(2)SH0702, l(2)SH2 0702" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024249 cato cousin of atonal http://flybase.org/reports/FBgn0024249 - protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR032664 neurogenesis ; GO:0022008 | inferred from electronic annotation with InterPro:IPR032664 sensory organ development ; GO:0007423 | inferred from mutant phenotype sensory organ development ; GO:0007423 | traceable author statement" - "Cato, DATH-B, CG7760, cato, bHLHa12" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR032664:Protein atonal/amos/lin-32" CG7760 11-Aug-17 DroID_v2017_08 "Drer\neurod1, Drer\atoh1b, Drer\atoh1a, Drer\ptf1a, Drer\si:ch211-246m6.4, Drer\atoh1c, Drer\neurod6b, Drer\nhlh2, Drer\scxb, Drer\neurod4, Drer\tcf15, Drer\neurod6a, Drer\atoh7, Drer\scxa" - "Cele\ngn-1, Cele\cnd-1, Cele\lin-32, Cele\hlh-15, Cele\hlh-13, Cele\hlh-3, Cele\hlh-12" "Xtro\scx, Xtro\neurod6, Xtro\tcf15, Xtro\atoh7, Xtro\neurod4, Xtro\nhlh1, Xtro\atoh1, Xtro\ptf1a" "Mmus\Ascl5, Mmus\Scx, Mmus\Neurod1, Mmus\Atoh7, Mmus\Neurod4, Mmus\Bhlha15, Mmus\Tcf15, Mmus\Atoh1, Mmus\Neurod6" "Hsap\ATOH1, Hsap\NEUROD4, Hsap\TCF15, Hsap\ASCL5, Hsap\NEUROD6, Hsap\NEUROD1, Hsap\PTF1A, Hsap\SCX, Hsap\ATOH7, Hsap\NHLH2" " larval stage , embryonic stage | stage 11-13 , embryonic stage | stage 10-13 , embryonic stage | stage 10,11 , embryonic stage | stage 10 " " peripheral nervous system

, sensory mother cell

, embryonic peripheral nervous system

, chordotonal organ precursor cell

, external sensory organ precursor cell

, imaginal disc

, C1 chordotonal organ precursor cell

" "viable,neuroanatomy defective" "chordotonal organ,ectopic,macrochaeta,scolopidium,scolopidial neuron,supernumerary,abdominal lch1 neuron" FBgn0266727 CR45200 - http://flybase.org/reports/FBgn0266727 non_protein_coding_gene - - - CR45200 - CR45200 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062700 EP1113 EP1113 http://flybase.org/reports/FBgn0062700 gene - - - "EP(3)1113, EP1113" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031805 CG9505 - http://flybase.org/reports/FBgn0031805 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG9505 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG9505 11-Aug-17 DroID_v2017_08 "Drer\phex, Drer\ece1, Drer\mmel1, Drer\ece2b" - "Cele\nep-13, Cele\nep-21, Cele\nep-6, Cele\nep-17, Cele\nep-7, Cele\nep-8, Cele\nep-23, Cele\nep-3, Cele\nep-9, Cele\nep-19, Cele\nep-5, Cele\nep-10, Cele\nep-16, Cele\nep-20, Cele\nep-18, Cele\nep-12, Cele\nep-26, Cele\nep-24" "Xtro\ece2, Xtro\ecel1, Xtro\ece1, Xtro\mmel1" "Mmus\Ece2, Mmus\Mme, Mmus\Phex, Mmus\Mmel1, Mmus\Ecel1, Mmus\Kel, Mmus\Ece1" "Hsap\MME, Hsap\ECE1, Hsap\PHEX, Hsap\ECEL1, Hsap\MMEL1, Hsap\KEL, Hsap\ECE2" viable FBgn0001086 fzy fizzy http://flybase.org/reports/FBgn0001086 - protein_coding_gene anaphase-promoting complex binding ; GO:0010997 | inferred from electronic annotation with InterPro:IPR033010 ubiquitin-protein transferase activator activity ; GO:0097027 | inferred from electronic annotation with InterPro:IPR033010 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from direct assay female meiosis I ; GO:0007144 | inferred from genetic interaction with cort female meiosis II ; GO:0007147 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype positive regulation of ubiquitin protein ligase activity ; GO:1904668 | inferred from sequence or structural similarity with HGNC:24824 protein catabolic process ; GO:0030163 | inferred from mutant phenotype anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from sequence or structural similarity with HGNC:24824 neurogenesis ; GO:0022008 | inferred from mutant phenotype neuronal stem cell population maintenance ; GO:0097150 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of exit from mitosis ; GO:0007096 | traceable author statement negative regulation of necrotic cell death ; GO:0060547 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | traceable author statement kinetochore ; GO:0000776 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay anaphase-promoting complex ; GO:0005680 | inferred from direct assay kinetochore ; GO:0000776 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement anaphase-promoting complex ; GO:0005680 | inferred from sequence or structural similarity with HGNC:24824 spindle ; GO:0005819 | inferred from direct assay centrosome ; GO:0005813 | traceable author statement "cdc20, CDC20, Cdc20/Fizzy, cdc20/fizzy, Cdc20, Fizzy, Cdc20[Fzy], Cdc20[fizzy], BG:DS02740.14, dFZY, CG4274, fzy, Fzy, Cdc20/Fzy, Fzy/Cdc20, dCDC20, FZY" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR033010:The WD repeat Cdc20/Fizzy family, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG4274 11-Aug-17 DroID_v2017_08 "Drer\fzr1b, Drer\fzr1a, Drer\cdc20" "Scer\CDH1, Scer\CDC20, Scer\AMA1" "Cele\fzy-1, Cele\fzr-1" "Xtro\cdc20, Xtro\fzr1" "Mmus\Fzr1, Mmus\Cdc20b, Mmus\Cdc20" "Hsap\CDC20B, Hsap\FZR1, Hsap\CDC20" " embryonic stage | stage 14 , embryonic stage | stage 11 , embryonic stage | stage 5-10 " " neuroblast | restricted

, embryonic central nervous system | presumptive

,

ubiquitous , ganglion mother cell | restricted

" "neuroanatomy defective,locomotor behavior defective,somatic clone,progressive,visible,wild-type,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,heat sensitive,meiotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage" "neuroblast,neuropil,somatic clone,wing,mitotic cell cycle & epidermis & embryo | ventral,mitotic cell cycle & spindle & epidermis & embryo | ventral,female germline stem cell,germline clone,embryonic ventral nervous system,embryonic ventral epidermis,spindle | embryonic stage,mitotic cell cycle,mitosis & nuclear chromosome,embryonic/larval optic lobe,posterior compartment,embryonic/larval neuroblast,ganglion mother cell,trichogen cell" DRSC03534 IE -0.762369643 -3.972417903 -1.465568427 -4.982800005 -0.506211735 1.238405932 FBgn0058175 CG40175 - http://flybase.org/reports/FBgn0058175 protein_coding_gene - - - CG40175 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262894 CG43249 - http://flybase.org/reports/FBgn0262894 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43249, lincRNA.583" - CG43249 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019754 l(1)7B lethal (1) 7B http://flybase.org/reports/FBgn0019754 - gene - - - l(1)7B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002156 l(2)MV lethal (2) MV http://flybase.org/reports/FBgn0002156 - gene - - - l(2)MV - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive,fertile" FBgn0025918 mei-99 mei-99 http://flybase.org/reports/FBgn0025918 - gene - reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - mei-99 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004395 unk unkempt http://flybase.org/reports/FBgn0004395 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model DNA binding ; GO:0003677 | non-traceable author statement zinc ion binding ; GO:0008270 | non-traceable author statement larval development ; GO:0002164 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype neuron differentiation ; GO:0030182 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG4620, unk" "IPR000571:Zinc finger, CCCH-type, IPR001841:Zinc finger, RING-type" CG4620 11-Aug-17 DroID_v2017_08 "Drer\unkl, Drer\unk" - Cele\C34D10.2 "Xtro\unkl, Xtro\unk" "Mmus\Unk, Mmus\Unkl" "Hsap\UNK, Hsap\UNKL" " embryonic stage | stage 1-15 , embryonic stage , embryonic stage | stage 13-17 " "

ubiquitous , embryonic central nervous system

" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,viable,visible,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic head,ommatidium,wing,scutellar bristle,trichogen cell" DRSC17093 E -0.489287832 -0.188488417 0.269309836 -1.519441135 -0.0451476 0.17268388 FBgn0014417 CG13397 - http://flybase.org/reports/FBgn0014417 FBgn0032041 protein_coding_gene alpha-N-acetylglucosaminidase activity ; GO:0004561 | inferred from sequence or structural similarity - - "ESTS:172F5T, 172F5T, anon-sts19, CG13397" "IPR007781:Alpha-N-acetylglucosaminidase, IPR017853:Glycoside hydrolase superfamily, IPR024240:Alpha-N-acetylglucosaminidase, N-terminal, IPR024732:Alpha-N-acetylglucosaminidase, C-terminal, IPR024733:Alpha-N-acetylglucosaminidase, tim-barrel domain" CG13397 11-Aug-17 DroID_v2017_08 Drer\naglu - Cele\K09E4.4 Xtro\naglu Mmus\Naglu Hsap\NAGLU "viable,fertile" FBgn0014889 Su(phl)9 Suppressor of pole hole 9 http://flybase.org/reports/FBgn0014889 - gene - - - "Su(D-raf)9, Su(phl)9" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260487 CG42534 - http://flybase.org/reports/FBgn0260487 protein_coding_gene - - - "CG42534, CG13980, CG14264, CG6599" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG42534 11-Aug-17 DroID_v2017_08 "Drer\ankdd1b, Drer\ankdd1a, Drer\si:ch211-203b8.6, Drer\ppp1r12c, Drer\ankk1" - "Cele\mlt-4, Cele\ikb-1, Cele\nphp-2" "Xtro\shank1, Xtro\ankdd1a, Xtro\ankhd1" "Mmus\Ankdd1a, Mmus\Ankdd1b, Mmus\Ankrd65, Mmus\Ppp1r12a" "Hsap\ANKRD65, Hsap\PLEKHO2, Hsap\ANKDD1B" FBgn0265928 CR44717 - http://flybase.org/reports/FBgn0265928 non_protein_coding_gene - - - "CR44717, lincRNA.504" - CR44717 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000292 Cg16-17 Collagen-like 16-17 http://flybase.net/reports/FBgn0000292.html gene "DCg6, Cg6" 11-Aug-17 DroID_v2017_08 FBgn0001868 l(1)XC46 lethal (1) XC46 http://flybase.org/reports/FBgn0001868 - gene - - - l(1)XC46 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037603 CG11753 - http://flybase.org/reports/FBgn0037603 protein_coding_gene - protein targeting to Golgi ; GO:0000042 | inferred from biological aspect of ancestor with PANTHER:PTN000310658 Golgi to plasma membrane protein transport ; GO:0043001 | inferred from biological aspect of ancestor with PANTHER:PTN000310658 Golgi to endosome transport ; GO:0006895 | inferred from biological aspect of ancestor with PANTHER:PTN000310658 integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000310658 trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000310658 CG11753 "IPR016973:Integral membrane protein SYS1, IPR019185:Integral membrane protein SYS1-related" CG11753 11-Aug-17 DroID_v2017_08 Drer\sys1 Scer\SYS1 Cele\T03F1.12 Xtro\sys1 Mmus\Sys1 "Hsap\SYS1, Hsap\DBNDD2" "body color defective,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum FBgn0264985 CR44136 - http://flybase.org/reports/FBgn0264985 non_protein_coding_gene - - - CR44136 - CR44136 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065945 l(2)SH0107 lethal (2) SH0107 http://flybase.org/reports/FBgn0065945 gene - - - "l(2)SH0107, l(2)SH2 0107" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065839 l(2)SH0328 lethal (2) SH0328 http://flybase.org/reports/FBgn0065839 gene - - - "l(2)SH0328, l(2)SH2 0328" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039249 CG11168 - http://flybase.org/reports/FBgn0039249 protein_coding_gene - - - CG11168 "IPR002110:Ankyrin repeat, IPR006020:PTB/PI domain, IPR011993:PH domain-like, IPR020683:Ankyrin repeat-containing domain, IPR033635:Ankyrin repeat and SAM domain-containing protein 1" CG11168 11-Aug-17 DroID_v2017_08 "Drer\anks1b, Drer\anks1ab, Drer\LOC564253" - Cele\C11E4.6 "Xtro\caskin1, Xtro\anks1a, Xtro\caskin2" "Mmus\Anks1, Mmus\Caskin2, Mmus\Anks1b" "Hsap\CASKIN2, Hsap\ANKS1B, Hsap\ANKS1A" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0034658 Grx1t "Glutaredoxin 1, testis-specific" http://flybase.org/reports/FBgn0034658 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR002109 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR002109 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR002109, InterPro:IPR011899" - "CG7975, Grx-1, Grx1t" "IPR002109:Glutaredoxin, IPR011899:Glutaredoxin, eukaryotic/virial, IPR012336:Thioredoxin-like fold, IPR014025:Glutaredoxin subgroup" CG7975 11-Aug-17 DroID_v2017_08 "Drer\glrx2, Drer\txnrd1, Drer\glrx" "Scer\GRX6, Scer\PRM4, Scer\GRX1, Scer\GRX8, Scer\GRX7, Scer\GRX2" "Cele\glrx-21, Cele\glrx-10, Cele\ZC334.7, Cele\glrx-22" "Xtro\glrx2, Xtro\glrx, Xtro\txnrd3, Xtro\txnrd1" "Mmus\Glrx2, Mmus\Glrx, Mmus\Txnrd3" "Hsap\TXNRD3, Hsap\GLRX, Hsap\TXNRD1, Hsap\GLRX2" viable FBgn0000015 Abd-B Abdominal B http://flybase.org/reports/FBgn0000015 "FBgn0002692, FBgn0010098, FBgn0026843, FBgn0026859, FBgn0038456, FBgn0038457" protein_coding_gene "transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "segment specification ; GO:0007379 | inferred from mutant phenotype genital disc sexually dimorphic development ; GO:0035263 | inferred from mutant phenotype salivary gland development ; GO:0007431 | non-traceable author statement negative regulation of female receptivity ; GO:0007621 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype external genitalia morphogenesis ; GO:0035261 | inferred from mutant phenotype negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement female genitalia development ; GO:0030540 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype male pigmentation ; GO:0048094 | inferred from direct assay open tracheal system development ; GO:0007424 | inferred from mutant phenotype positive regulation of apoptotic process involved in morphogenesis ; GO:1902339 | inferred from mutant phenotype positive regulation of developmental pigmentation ; GO:0048087 | non-traceable author statement determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype negative regulation of striated muscle tissue development ; GO:0045843 | inferred from mutant phenotype imaginal disc-derived genitalia development ; GO:0007484 | traceable author statement genital disc development ; GO:0035215 | traceable author statement sex differentiation ; GO:0007548 | non-traceable author statement specification of segmental identity, abdomen ; GO:0007385 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement heart development ; GO:0007507 | non-traceable author statement sex-specific pigmentation ; GO:0048071 | traceable author statement sperm storage ; GO:0046693 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype midgut development ; GO:0007494 | traceable author statement male gonad development ; GO:0008584 | inferred from mutant phenotype gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype negative regulation of cardioblast cell fate specification ; GO:0009997 | inferred from mutant phenotype neuroendocrine cell differentiation ; GO:0061101 | inferred from mutant phenotype specification of segmental identity, abdomen ; GO:0007385 | non-traceable author statement male genitalia development ; GO:0030539 | inferred from mutant phenotype pole cell migration ; GO:0007280 | traceable author statement genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern imaginal disc-derived female genitalia development ; GO:0007486 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay developmental pigmentation ; GO:0048066 | non-traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "Abd-B, AbdB, iab-7, iab-6, Fab7, Fab-7, iab-8, AdbB, Abd-b, iab-5, AbdB-II, AbdB-I, abd-B, Abd B, iab6, Mcp, DROABDB, pH189, ABDB, AbdB(CA)[[26]], abdB, MCP, FAB, Mc, iab9, iab8, iab7, iab5, Tab, Sab, twig, tuh-3, l(3)89Ed, iab, iab8.9, Uab-5[Sab], CG10291, CG11648, Iab-7, IAB5, IAB8, bex, IAB 5, Droabdb, BX-C, iab-8,9, ABD-B, Fab-8, AbdBm, Fab-6, Abd0B, DmAbdB, Abdb, IAB7" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG11648 11-Aug-17 DroID_v2017_08 "Drer\hoxb7a, Drer\hoxd9a, Drer\pou5f3, Drer\lmx1bb, Drer\hoxa4a, Drer\hoxa9b, Drer\hoxc13b, Drer\pou3f1, Drer\hoxa13b, Drer\hoxc12a, Drer\hoxd11a, Drer\hoxb10a, Drer\hoxc11a, Drer\hoxa9a, Drer\hoxa11b, Drer\hoxd12a, Drer\pou3f3b, Drer\hoxa10b, Drer\pou3f2b, Drer\hoxc11b, Drer\hoxa11a, Drer\hoxb4a, Drer\hoxc12b, Drer\lmx1ba, Drer\hoxd10a, Drer\hoxb9a, Drer\hoxa13a, Drer\lmx1a, Drer\hoxc9a, Drer\hoxd13a, Drer\hoxb13a, Drer\hoxc13a, Drer\pou2f3, Drer\hoxc10a" "Scer\YOX1, Scer\PHO2, Scer\YHP1" "Cele\egl-5, Cele\nob-1, Cele\lim-6, Cele\ceh-6, Cele\php-3" "Xtro\hoxc10, Xtro\hoxb9, Xtro\hoxa13, Xtro\hoxa11, Xtro\hoxd13, Xtro\hoxd9, Xtro\hoxc9, Xtro\pou3f1, Xtro\hoxc12, Xtro\hoxd10, Xtro\hoxa7, Xtro\hoxc13, Xtro\hoxc11" "Mmus\Hoxd13, Mmus\Pou3f4, Mmus\Hoxb9, Mmus\Hoxa4, Mmus\Hoxd10, Mmus\Hoxc12, Mmus\Hoxa7, Mmus\Hoxa10, Mmus\Hoxb4, Mmus\Hoxa9, Mmus\Hoxa11, Mmus\Pou3f1, Mmus\Hoxd9, Mmus\Hoxc4, Mmus\Hoxb13, Mmus\Lmx1b, Mmus\Hoxc13, Mmus\Hoxc9, Mmus\Hoxb7, Mmus\Lmx1a, Mmus\Hoxc11, Mmus\Hoxc10, Mmus\Hoxd4, Mmus\Hoxa13, Mmus\Hoxd12, Mmus\Pou3f2, Mmus\Hoxd11, Mmus\Pou3f3" "Hsap\HOXB9, Hsap\HOXA4, Hsap\HOXA10, Hsap\HOXD9, Hsap\HOXC11, Hsap\HOXB13, Hsap\HOXA9, Hsap\HOXC12, Hsap\HOXB7, Hsap\HOXA11, Hsap\HOXA7, Hsap\HOXC10, Hsap\HOXD12, Hsap\HOXB4, Hsap\POU3F3, Hsap\HOXD13, Hsap\HOXC9, Hsap\POU3F4, Hsap\POU3F1, Hsap\HOXC13, Hsap\HOXC4, Hsap\POU3F2, Hsap\HOXA13, Hsap\HOXD11, Hsap\HOXD10, Hsap\HOXD4, Hsap\LMX1B, Hsap\LMX1A" " embryonic stage | late , larval stage , embryonic stage | cellular blastoderm , embryonic stage | extended germ band , adult stage , embryonic stage | 4-10 hr , embryonic stage | 4-7 hr , embryonic stage | 10-13 hr , embryonic stage , pupal stage " " parasegment 13

, parasegment 14

, parasegment 14 &&of embryonic central nervous system

, epidermis &&of abdominal segment 9

, parasegment 10--14

, parasegment 11--13 &&of embryonic central nervous system

, parasegment 14 &&of epidermis

" " embryonic stage | mid-late , embryonic stage | mid & late , embryonic stage | stage 13 , embryonic stage | stage 12 , embryonic stage , larval stage | third instar , embryonic stage | stage 13-14 , embryonic stage | stage 11-13 , embryonic stage | stage 11 , embryonic stage | late , embryonic stage | stage >=12 , embryonic stage | stage 10 , larval stage , embryonic stage | stage >12 " " proctodeum

{ + Pc- } , ectoderm &&of parasegment 13--15

, ectoderm &&of parasegment 10--13

, visceral mesoderm

, parasegment 11--14

, ectoderm

, mesoderm &&of parasegment 11--15

, parasegment 10--14

, Malpighian tubule

, male genital disc | restricted

, female genital disc | restricted

, parasegment 13

, parasegment 12--14 &&of embryonic central nervous system

, visceral mesoderm &&of embryonic/larval hindgut &&of parasegment 13--15

, parasegment 11--15

, visceral mesoderm &&of parasegment 11--14

, embryonic dorsal vessel |posterior

, parasegment 14

, parasegment 13--15

, larval fat body | posterior

, visceral mesoderm &&of parasegment 11--13 &&of embryonic/larval midgut

, spiracle

, parasegment 11--13

, central nervous system

{ + Pc- } " "visible,homeotic,lethal,partially,recessive,female sterile,fertile,lethal - all die before end of larval stage,some die during larval stage,dominant,male sterile,male limited,mating defective,viable,female,male,somatic clone,body color defective,sterile,semi-sterile,good,cell autonomous,neuroanatomy defective,decreased cell death" "gonad,precursor,genitalia,female,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,parasegment 10,parasegment 11,parasegment 12,parasegment 13,abdominal tergite 5,male,abdominal tergite 7,abdominal sternite 6,ectopic,tergite,sternite,abdominal sternite 7,trichome,abdominal tergite 8,adult abdominal segment 6,adult abdominal segment 7,female genitalia,embryonic abdominal segment 8,abdominal 8 ventral denticle belt,posterior spiracle primordium,testis,male genitalia,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 8,embryonic/larval posterior spiracle,abdominal tergite 6,anal plate,abdominal tergite 5 & trichomeAbd-BS10),male limited,adult abdominal sensillum,abdominal sternite 5,male accessory gland secondary cell,head,adult head,terminalia,female terminalia,male terminalia,female analia,male analia,parasegment 14,embryonic abdominal segment 9,gonopod thorn bristle,mesothoracic segment,abdominal 9 ventral denticle belt,filzkorper,somatic clone,sclerite & abdominal segment 8 & embryo | somatic clone,sclerite,denticle & embryonic abdominal segment 9 | somatic clone,denticle,parasegment 9,abdominal segment 4,adult abdomen,eye,ommatidium,ocellus,occiput,head bristle,antenna,occipital bristle,frons,eye-antennal disc,scutum,adult cuticle & abdominal segment 3 | male,adult cuticle & abdominal segment 4 | male,leg,adult abdominal segment 1,genital disc primordium,adult antennal segment,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,female accessory gland,spermathecum,denticle belt,sensillum basiconicum,embryonic segment,sense organ,larval abdominal segment,anterior,adult abdominal segment 3,adult abdominal segment 2,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,spiracular sense organ (obsolete FBbt00000431),larval head,abdominal segment,prothoracic segment,metathoracic segment,tracheal system,procephalic segment,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,T1 beard,distal,arista,third segment of antenna,heart primordium,larval abdominal segment 5,larval abdominal segment 4,embryonic/larval spiracle,epiproct,abdominal segment 9,dMP2 neuron,MP1 neuron,embryonic/first instar larval cuticle,scutellar bristle,gonadal sheath proper primordium,dMP2 neuron | embryonic stage 17,MP1 neuron | embryonic stage 17,dorsal,ventral,adult mesothoracic segment,adult metathoracic segment,abdominal segment 1,abdominal segment 2,abdominal segment 3,embryonic peripheral nervous system & embryonic abdominal segment 8,stigmatophore,cell autonomous,unguis,tibia,tarsal segment,mesothoracic tibial apical bristle,vulva,female gonopod,hypandrium,penis,clasper,second segment of antenna,neuroblast NB6-4 of abdomen,neuroblast NB6-4 of thorax,cardioblast,embryonic/larval heart,embryonic somatic muscle,embryonic dorsal vessel,fat body/gonad primordium,wing vein,wing margin,embryonic tritocerebrum,scutellum,scutum & macrochaetaC-765,wing,gonad | embryonic stage,pretarsus,parasegment 8,trichogen cell,embryonic/larval dorsal trunk,embryonic/larval tracheal system" FBgn0033542 CG12309 - http://flybase.org/reports/FBgn0033542 protein_coding_gene - - - CG12309 "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class" CG12309 11-Aug-17 DroID_v2017_08 "Drer\ca6, Drer\ca14, Drer\ptprga, Drer\ca9, Drer\ca4c, Drer\ca8, Drer\ca5a, Drer\ca7, Drer\ca10b, Drer\ca2, Drer\cahz, Drer\ca4b, Drer\ca15b, Drer\ca16b, Drer\zgc:153760, Drer\ca10a, Drer\car15, Drer\ca15c, Drer\ca12, Drer\ca15a, Drer\ca4a" - "Cele\cah-5, Cele\cah-3" "Xtro\ca11, Xtro\ca6, Xtro\ca14, Xtro\ca4, Xtro\LOC779564, Xtro\ca7, Xtro\ca8, Xtro\ca5b, Xtro\ca12, Xtro\ca1, Xtro\ca10, Xtro\ca3, Xtro\ca2" "Mmus\Car6, Mmus\Car9, Mmus\Car5b, Mmus\Car5a, Mmus\Car7, Mmus\Car3, Mmus\Car1, Mmus\Car14, Mmus\Car10, Mmus\Car2, Mmus\Car11, Mmus\Ptprg, Mmus\Car15, Mmus\Car13, Mmus\Car12, Mmus\Car4, Mmus\Car8" "Hsap\CA5B, Hsap\CA10, Hsap\CA2, Hsap\CA8, Hsap\CA11, Hsap\CA7, Hsap\CA13, Hsap\CA12, Hsap\PTPRG, Hsap\CA14, Hsap\CA3, Hsap\CA1, Hsap\CA5A, Hsap\CA9, Hsap\CA4, Hsap\CA6" "viable,body color defective" mesothoracic tergum DRSC24093 IK 1.527097691 0.829892684 0.24072524 0.111083419 1.848060994 1.599467847 FBgn0032293 Dpy-30L1 Dpy-30-like 1 http://flybase.org/reports/FBgn0032293 protein_coding_gene histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000599398 chromatin silencing at telomere ; GO:0006348 | inferred from biological aspect of ancestor with PANTHER:PTN000599398 histone H3-K4 methylation ; GO:0051568 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype MLL1/2 complex ; GO:0044665 | inferred from sequence or structural similarity with HGNC:24590 MLL3/4 complex ; GO:0044666 | inferred from direct assay Set1C/COMPASS complex ; GO:0048188 | inferred from direct assay "CG6444, dpy-30L1, Dpy-30L1, dDPY30-L1, Dpy30, dpy30, DPY30" IPR007858:Dpy-30 motif CG6444 11-Aug-17 DroID_v2017_08 Drer\dpy30 Scer\SDC1 "Cele\F34D10.6, Cele\R05G6.5, Cele\dpy-30" "Xtro\ak7, Xtro\dpy30" Mmus\Dpy30 "Hsap\DPY30, Hsap\MEMO1" "chemical sensitive,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0030437 hec hector http://flybase.org/reports/FBgn0030437 protein_coding_gene calcitonin receptor activity ; GO:0004948 | inferred from electronic annotation with InterPro:IPR003287 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model calcitonin receptor activity ; GO:0004948 | inferred from sequence or structural similarity "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000832, InterPro:IPR003287, InterPro:IPR017983 cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model male courtship behavior ; GO:0008049 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000832 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "anon-WO0170980.2, anon-WO0170980.1, CG4395, hec" "IPR000832:GPCR, family 2, secretin-like, IPR001879:GPCR, family 2, extracellular hormone receptor domain, IPR003287:GPCR, family 2, calcitonin receptor family, IPR017981:GPCR, family 2-like, IPR017983:GPCR, family 2, secretin-like, conserved site" CG4395 11-Aug-17 DroID_v2017_08 "Drer\ghrhra, Drer\gipr, Drer\pth1rb, Drer\calcrla, Drer\vipr1b, Drer\pth1ra, Drer\ghrhrb, Drer\gcgrb, Drer\ghrhr2, Drer\crhr1, Drer\calcrlb, Drer\vipr1a, Drer\vipr2, Drer\calcrl2, Drer\adcyap1r1b, Drer\adcyap1r1a, Drer\crhr2, Drer\calcr, Drer\pth2r, Drer\si:dkeyp-4h4.1, Drer\gcgra" - "Cele\seb-2, Cele\seb-3" "Xtro\gipr, Xtro\vipr1, Xtro\crhr1.1, Xtro\pth1r, Xtro\pth2r, Xtro\adcyap1r1, Xtro\crhr1.2, Xtro\calcrl, Xtro\gcgr" "Mmus\Adcyap1r1, Mmus\Calcrl, Mmus\Ghrhr, Mmus\Sctr, Mmus\Glp2r, Mmus\Glp1r, Mmus\Crhr2, Mmus\Calcr, Mmus\Gcgr, Mmus\Pth1r, Mmus\Crhr1, Mmus\Vipr2, Mmus\Gipr, Mmus\Vipr1, Mmus\Pth2r" "Hsap\VIPR2, Hsap\CRHR2, Hsap\PTH1R, Hsap\CALCR, Hsap\CALCRL, Hsap\PTH2R, Hsap\CRHR1, Hsap\GLP2R, Hsap\ADCYAP1R1, Hsap\GLP1R, Hsap\SCTR, Hsap\GCGR, Hsap\GIPR, Hsap\GHRHR, Hsap\VIPR1" "mating behavior defective,male limited,viable" FBgn0261564 Reep1 Receptor expression enhancing protein 1 http://flybase.org/reports/FBgn0261564 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG42678, CG9848, CG30190, BcDNA:RE29641, BcDNA:LD42159, anon-WO0118547.113, CG30193, Reep1, D-reep1, reep1" IPR004345:TB2/DP1/HVA22-related protein CG42678 11-Aug-17 DroID_v2017_08 "Drer\reep2, Drer\reep1, Drer\reep3b, Drer\reep3a" Scer\YOP1 "Cele\W01D2.3, Cele\T19C3.4, Cele\C06E1.1" "Xtro\reep3, Xtro\reep4, Xtro\reep2" "Mmus\Reep2, Mmus\Reep3, Mmus\Reep1, Mmus\Reep4" "Hsap\REEP2, Hsap\REEP3, Hsap\REEP4, Hsap\REEP1" FBgn0267236 CG45676 - http://flybase.org/reports/FBgn0267236 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45676 - CG45676 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267807 CR46132 - http://flybase.org/reports/FBgn0267807 non_protein_coding_gene - - - CR46132 - CR46132 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038478 cal1 chromosome alignment defect 1 http://flybase.org/reports/FBgn0038478 protein_coding_gene "histone binding ; GO:0042393 | inferred from electronic annotation with InterPro:IPR018465 protein binding ; GO:0005515 | inferred from physical interaction with cid protein binding, bridging ; GO:0030674 | inferred from physical interaction with cid, Cenp-C" "positive regulation of CENP-A containing nucleosome assembly ; GO:1903099 | inferred from direct assay protein localization to kinetochore ; GO:0034501 | inferred from mutant phenotype regulation of kinetochore assembly ; GO:0090234 | inferred from direct assay protein localization to chromosome, centromeric region ; GO:0071459 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype" "kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay" "cal1, CG5148, Cal1, CLD2, CAL1" IPR018465:Centromere protein Scm3/HJURP CG5148 11-Aug-17 DroID_v2017_08 "Drer\mtdha, Drer\mtdhb" - - - Mmus\Mtdh Hsap\MTDH "neuroanatomy defective,recessive,meiotic cell cycle defective,semidominant,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,lethal,mitotic cell cycle defective" "nucleus,embryonic/larval central nervous system,presumptive embryonic/larval central nervous system,trichogen cell,mesothoracic tergum" FBgn0024142 Bip-p15 Bcd interacting protein p15 http://flybase.org/reports/FBgn0024142 - gene - - - "p15, Bip-p15" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037512 CG2616 - http://flybase.org/reports/FBgn0037512 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 CG2616 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG2616 11-Aug-17 DroID_v2017_08 "Drer\slc25a39, Drer\slc25a40" Scer\MTM1 Cele\C16C10.1 "Xtro\slc25a39, Xtro\slc25a40" "Mmus\Slc25a40, Mmus\Slc25a39" "Hsap\SLC25A40, Hsap\SLC25A39" viable FBgn0259642 B2036 - http://flybase.org/reports/FBgn0259642 gene - - - B2036 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "submarginal cell,anterior crossvein,wing vein L3,wing vein" FBgn0000226 bsc bent scutellars http://flybase.org/reports/FBgn0000226 - gene - - - bsc - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,poor,fertile,reduced,male fertile" "scutellar bristle,eye,wing,macrochaeta" FBgn0046769 CG32331 - http://flybase.org/reports/FBgn0046769 protein_coding_gene - - - "BcDNA:LD40851, CG32331" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21332 I -0.404863425 -1.878941061 0.031248613 0.512350503 -1.200168432 0.586933741 FBgn0265214 fs(2)Z2-3774 - http://flybase.org/reports/FBgn0265214 gene - - - fs(2)Z2-3774 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0005250 l(3)R340 lethal of Roberts 340 http://flybase.org/reports/FBgn0005250 - gene - - - "l(3)340, l(3)R340" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0003199 rai raisin http://flybase.org/reports/FBgn0003199 - gene - - - rai - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,recessive,visible" pigment cell FBgn0005683 pie pineapple eye http://flybase.org/reports/FBgn0005683 "FBgn0002088, FBgn0002668, FBgn0032245" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype - "mat(2)QM47, l(2)54, l(2)31Ek, mat(2)earlyQM47, mat(2)ea-E, CG5354, pie" "IPR001965:Zinc finger, PHD-type, IPR034732:Extended PHD (ePHD) domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5354 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-37e10.1, Drer\phf11, Drer\si:ch211-57f7.7, Drer\phf6, Drer\g2e3" - - "Xtro\phf6, Xtro\g2e3" "Mmus\Phf11a, Mmus\Phf7, Mmus\G2e3, Mmus\Phf11d, Mmus\Gm6904, Mmus\Phf6, Mmus\Phf11c, Mmus\Phf11b" "Hsap\G2E3, Hsap\PHF6, Hsap\PHF11, Hsap\PHF7" "lethal,sterile,recessive,developmental rate defective,partially lethal - majority die,female sterile,male semi-sterile,viable,increased cell death,somatic clone,partially lethal - majority live,visible,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,neuroanatomy defective,female fertile" "eye,ommatidium,somatic clone,photoreceptor cell,cone cell,pigment cell,eye photoreceptor cell,ventral thoracic disc,wing disc,eye disc,wing,embryonic/larval neuroblast,ganglion mother cell" FBgn0029840 raptor raptor http://flybase.org/reports/FBgn0029840 protein_coding_gene "protein binding, bridging ; GO:0030674 | inferred from biological aspect of ancestor with PANTHER:PTN000304084" positive regulation of cell growth ; GO:0030307 | inferred from biological aspect of ancestor with PANTHER:PTN000304084 oogenesis ; GO:0048477 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with Rheb eclosion ; GO:0007562 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of protein phosphorylation ; GO:0001934 | inferred from mutant phenotype TOR signaling ; GO:0031929 | inferred from biological aspect of ancestor with PANTHER:PTN000304084 cellular response to starvation ; GO:0009267 | inferred from biological aspect of ancestor with PANTHER:PTN000304084 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype positive regulation of protein serine/threonine kinase activity ; GO:0071902 | inferred from biological aspect of ancestor with PANTHER:PTN000304084 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from biological aspect of ancestor with PANTHER:PTN000304084 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cellular response to amino acid stimulus ; GO:0071230 | inferred from biological aspect of ancestor with PANTHER:PTN000304084 regulation of cell size ; GO:0008361 | inferred from biological aspect of ancestor with PANTHER:PTN000304084 autophagy ; GO:0006914 | inferred from mutant phenotype TORC1 complex ; GO:0031931 | inferred from biological aspect of ancestor with PANTHER:PTN000304084 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000304084 "raptor, dRaptor, CG4320, Raptor, raptor/CG4320, dRap, 4320" "IPR029347:Raptor, N-terminal CASPase-like domain, IPR011989:Armadillo-like helical, IPR004083:Regulatory associated protein of TOR, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR016024:Armadillo-type fold, IPR000357:HEAT repeat" CG4320 11-Aug-17 DroID_v2017_08 Drer\rptor Scer\KOG1 Cele\daf-15 Xtro\rptor Mmus\Rptor Hsap\RPTOR "neuroanatomy defective,size defective,decreased cell size,decreased cell number,visible,lethal" "NMJ bouton | third instar larval stage,wing" DRSC18359 I -1.306402847 3.25450797 -0.59535879 -0.035422718 -0.131587717 0.80808625 FBgn0065359 l(2)SH1750 lethal (2) SH1750 http://flybase.org/reports/FBgn0065359 gene - - - "l(2)SH1750, l(2)SH2 1750" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010366 anon-32D anon-32D http://flybase.org/reports/FBgn0010366 - gene - - - "Ubx-t9, anon-32D" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085744 CR40561 - http://flybase.org/reports/FBgn0085744 rRNA_gene - - - CR40561 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263742 CG43667 - http://flybase.org/reports/FBgn0263742 protein_coding_gene - - - "CG43667, CG15226" - CG43667 11-Aug-17 DroID_v2017_08 "Drer\zgc:165600, Drer\lamp2, Drer\lamp1, Drer\si:ch211-212k18.7" - "Cele\lmp-1, Cele\lmp-2" - "Mmus\Lamp1, Mmus\Cd68, Mmus\Lamp2, Mmus\Lamp3, Mmus\Lamp5" "Hsap\LAMP1, Hsap\LAMP3, Hsap\LAMP2, Hsap\CD68, Hsap\LAMP5" FBgn0013305 Nmda1 N-methyl-D-aspartate receptor-associated protein http://flybase.org/reports/FBgn0013305 - protein_coding_gene - regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype - "NMDARA1, DRONMDA, dNMDARA1, cDNA2, CG3798, Nmda1, dTmbim3" IPR006214:Bax inhibitor 1-related CG3798 11-Aug-17 DroID_v2017_08 "Drer\tmbim1, Drer\grinab, Drer\faim2a, Drer\si:ch211-284o19.8, Drer\grinaa, Drer\tmbim4, Drer\LOC566927, Drer\zgc:110410, Drer\faim2b" Scer\BXI1 "Cele\tag-120, Cele\xbx-6, Cele\Y42H9AR.2, Cele\tmbi-4" "Xtro\grina, Xtro\faim2, Xtro\tmbim1, Xtro\tmbim4" "Mmus\Grina, Mmus\Tmbim1, Mmus\Tmbim4, Mmus\Tmbim7, Mmus\Faim2" "Hsap\GRINA, Hsap\TMBIM1, Hsap\FAIM2, Hsap\TMBIM4" viable heart primordium FBgn0001863 l(1)VE807 lethal (1) VE807 http://flybase.org/reports/FBgn0001863 - gene - - - l(1)VE807 - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005404 l(1)10Cg lethal (1) 10Cg http://flybase.org/reports/FBgn0005404 - gene - - - l(1)10Cg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065778 l(2)SH0447 lethal (2) SH0447 http://flybase.org/reports/FBgn0065778 gene - - - "l(2)SH0447, l(2)SH2 0447" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036836 CG11619 - http://flybase.org/reports/FBgn0036836 protein_coding_gene starch binding ; GO:2001070 | inferred from electronic annotation with InterPro:IPR002044 glycerophosphocholine phosphodiesterase activity ; GO:0047389 | inferred from biological aspect of ancestor with PANTHER:PTN001120996 glycerophosphodiester phosphodiesterase activity ; GO:0008889 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 cellular phosphate ion homeostasis ; GO:0030643 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 glycerophospholipid catabolic process ; GO:0046475 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 - CG11619 "IPR030395:Glycerophosphodiester phosphodiesterase domain, IPR000909:Phosphatidylinositol-specific phospholipase C, X domain, IPR002044:Carbohydrate binding module family 20, IPR013783:Immunoglobulin-like fold, IPR013784:Carbohydrate-binding-like fold, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR033506:Glycerophosphodiester phosphodiesterase Gde1" CG11619 11-Aug-17 DroID_v2017_08 Drer\gpcpd1 "Scer\GDE1, Scer\PHO81" "Cele\gpcp-2, Cele\gpcp-1" - Mmus\Gpcpd1 Hsap\GPCPD1 viable DRSC09849 K 1.015241888 0.700768109 -0.061673317 -0.199184474 0.017372658 1.674695605 FBgn0032298 CG6724 - http://flybase.org/reports/FBgn0032298 protein_coding_gene - "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000463 | inferred from sequence or structural similarity with UniProtKB:Q9GZL7 neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000458000 maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000458000" "PeBoW complex ; GO:0070545 | inferred from biological aspect of ancestor with PANTHER:PTN000458000 plasma membrane ; GO:0005886 | inferred from direct assay PeBoW complex ; GO:0070545 | inferred from sequence or structural similarity with UniProtKB:Q9GZL7 cytosol ; GO:0005829 | inferred from direct assay preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000458000" CG6724 "IPR001680:WD40 repeat, IPR012972:NLE, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR028599:WD repeat WDR12/Ytm1" CG6724 11-Aug-17 DroID_v2017_08 Drer\wdr12 Scer\YTM1 Cele\wdr-12 Xtro\wdr12 Mmus\Wdr12 Hsap\WDR12 "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0033701 CG13171 - http://flybase.org/reports/FBgn0033701 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13171 - CG13171 11-Aug-17 DroID_v2017_08 - - Cele\F15G9.5 - - - viable FBgn0002108 l(2)85 lethal (2) 85 http://flybase.org/reports/FBgn0002108 - gene - - - l(2)85 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036975 CG5618 - http://flybase.org/reports/FBgn0036975 protein_coding_gene carboxy-lyase activity ; GO:0016831 | inferred from electronic annotation with InterPro:IPR002129 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 carboxylic acid metabolic process ; GO:0019752 | inferred from electronic annotation with InterPro:IPR002129 - CG5618 "IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG5618 11-Aug-17 DroID_v2017_08 "Drer\zgc:163121, Drer\gad2, Drer\csad, Drer\gad1a" - Cele\unc-25 "Xtro\gad2, Xtro\csad, Xtro\gad1.2, Xtro\gadl1, Xtro\gad1.1" "Mmus\Csad, Mmus\Gad1, Mmus\Gadl1, Mmus\Gad2" "Hsap\GAD1, Hsap\CSAD, Hsap\GADL1, Hsap\GAD2" "viable,fertile" FBgn0031552 CG15416 - http://flybase.org/reports/FBgn0031552 protein_coding_gene - - - CG15416 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262680 CR43150 - http://flybase.org/reports/FBgn0262680 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43150, CG43150, mdcds_33995" - CR43150 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069444 E(br)65 E(br)65 http://flybase.org/reports/FBgn0069444 gene molecular_function ; GO:0003674 | no biological data available dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available E(br)65 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/first instar larval cuticle,anterior" FBgn0002739 mgt midget http://flybase.org/reports/FBgn0002739 - gene - - - mgt - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,reduced,female,male fertile,visible,recessive" FBgn0045048 fs(1)260 female sterile (1) 260 http://flybase.org/reports/FBgn0045048 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)260 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "ovary,border follicle cell,nurse cell,supernumerary" FBgn0082319 LpR2::Mmus\Egf Egf http://flybase.org/reports/FBgn0082319 engineered_fusion_gene - - - LpR2::Mmus\Egf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005168 l(2)G563 lethal (2) G563 http://flybase.org/reports/FBgn0005168 - gene - - - l(2)G563 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035033 CG3548 - http://flybase.org/reports/FBgn0035033 protein_coding_gene - - - CG3548 IPR028002:Myb/SANT-like DNA-binding domain CG3548 11-Aug-17 DroID_v2017_08 - - - - Mmus\Msantd3 Hsap\MSANTD3 "viable,fertile" DRSC04387 E 0.949498679 0.40933099 1.91603909 -1.686024417 -0.649097544 -0.461686586 FBgn0065347 l(2)SH1811 lethal (2) SH1811 http://flybase.org/reports/FBgn0065347 gene - - - "l(2)SH1811, l(2)SH2 1811" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041721 snRNA:U12:73B snRNA:U12:73B http://flybase.org/reports/FBgn0041721 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U12 snRNP ; GO:0005693 | inferred from sequence or structural similarity "dU12, U12, CR32162, anon-WO0172774.79, snRNA:U12:73B, U12:73B, 73B U12" - CR32162 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028884 CG4892 - http://flybase.org/reports/FBgn0028884 protein_coding_gene - - - "DS04095.2, BG:DS04095.2, BcDNA:AT24169, CG4892" IPR026806:Protein CDV3 CG4892 11-Aug-17 DroID_v2017_08 Drer\cdv3 - - Xtro\cdv3 Mmus\Cdv3 Hsap\CDV3 "viable,fertile" DRSC01937 I 1.723887641 -0.431798428 -1.093632781 0.258722026 0.270787918 0.086115712 FBgn0043869 nompJ no mechanoreceptor potential J http://flybase.org/reports/FBgn0043869 gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - nompJ - - 11-Aug-17 DroID_v2017_08 - - - - - - "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective" "wing,leg,macrochaeta,adult antennal nerve" FBgn0060952 l(3)S036901b lethal (3) S036901b http://flybase.org/reports/FBgn0060952 gene - - - "0369/01, l(3)S036901b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0260273 GSd213 - http://flybase.org/reports/FBgn0260273 gene - - - GSd213 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014315 l(3)ry116 lethal (3) ry116 http://flybase.org/reports/FBgn0014315 - gene - - - l(3)ry116 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083039 snoRNA:Psi18S-301 snoRNA:Psi18S-301 http://flybase.org/reports/FBgn0083039 snoRNA_gene - - - "snoRNA:Psi18S-301, psi18s-301, Psi 18S-301, CR34614, chr3R:16400618..16400867" - CR34614 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065570 l(2)SH0970 lethal (2) SH0970 http://flybase.org/reports/FBgn0065570 gene - - - "l(2)SH0970, l(2)SH2 0970" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014372 pll::tor pll::tor http://flybase.org/reports/FBgn0014372 - engineered_fusion_gene - - - pll::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283464 mir-4966-2 mir-4966-2 stem loop http://flybase.org/reports/FBgn0283464 miRNA_gene - - - "mir-4966-2, dme-mir-4966-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0087018 l(3)61Df lethal (3) 61Df http://flybase.org/reports/FBgn0087018 gene - - - l(3)61Df - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die" FBgn0035262 CG18171 - http://flybase.org/reports/FBgn0035262 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18171 "IPR032675:Leucine-rich repeat domain, L domain-like" CG18171 11-Aug-17 DroID_v2017_08 Drer\tcte1 - - Xtro\tcte1 Mmus\Tcte1 Hsap\TCTE1 viable FBgn0036205 CG14131 - http://flybase.org/reports/FBgn0036205 protein_coding_gene - - - "CG14131, Pi3K68D" - CG14131 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0050208 tRNA:Trp-CCA-2-4 transfer RNA:Tryptophan-CCA 2-4 http://flybase.org/reports/FBgn0050208 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "CR30208, AE002575.trna1-TrpCCA, tRNA:W:CCA:AE002575-a, chr2R.trna45-TrpCCA, tRNA-Trp-CCA-2-4, tRNA:Trp-CCA-2-4, tRNA:CR30208, UGG" - CR30208 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004037 yea3 yeast 3 http://flybase.org/reports/FBgn0004037 - gene - - - yea3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267560 CR45900 - http://flybase.org/reports/FBgn0267560 non_protein_coding_gene - - - CR45900 - CR45900 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259650 B1521 - http://flybase.org/reports/FBgn0259650 gene - - - B1521 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "chaeta,ectopic,wing,distal" FBgn0058274 CG40274 - http://flybase.org/reports/FBgn0058274 protein_coding_gene - - - CG40274 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21725 K -0.45427785 0.510755802 -0.24317685 0.259994663 1.652206491 0.687832454 FBgn0085341 CG34312 - http://flybase.org/reports/FBgn0085341 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34312 - CG34312 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028035 l(3)S101310 lethal (3) S101310 http://flybase.org/reports/FBgn0028035 gene - - - "1013/10, l(3)S101310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0036678 CG11905 - http://flybase.org/reports/FBgn0036678 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay CG11905 IPR031942:Domain of unknown function DUF4774 CG11905 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002105 l(2)57Eb lethal (2) 57Eb http://flybase.org/reports/FBgn0002105 - gene - - - "l(2)57DEFb, l(2)57Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010903 l(3)06811 lethal (3) 06811 http://flybase.org/reports/FBgn0010903 - gene - - - l(3)06811 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015623 Cpr Cytochrome P450 reductase http://flybase.org/reports/FBgn0015623 - protein_coding_gene "FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR008254 NADPH-hemoprotein reductase activity ; GO:0003958 | inferred from biological aspect of ancestor with PANTHER:PTN000453822" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR003097, InterPro:IPR017927, InterPro:IPR017938, InterPro:IPR023173, InterPro:IPR023208 biological_process ; GO:0008150 | no biological data available" endomembrane system ; GO:0012505 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "DMR, DmCPR, cpr, NCPR, CPR, P450, CG11567, Cpr, CCR" "IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR001709:Flavoprotein pyridine nucleotide cytochrome reductase, IPR003097:FAD-binding, type 1, IPR008254:Flavodoxin/nitric oxide synthase, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel, IPR029039:Flavoprotein-like domain, IPR001094:Flavodoxin-like, IPR023208:NADPH-cytochrome P450 reductase" CG11567 11-Aug-17 DroID_v2017_08 "Drer\porb, Drer\pora, Drer\nos2a, Drer\nos1, Drer\nos2b, Drer\mtrr" "Scer\NCP1, Scer\MET10" Cele\emb-8 "Xtro\nos3, Xtro\por, Xtro\nos2, Xtro\mtrr, Xtro\nos1" "Mmus\Nos2, Mmus\Mtrr, Mmus\Nos1, Mmus\Por, Mmus\Nos3" "Hsap\POR, Hsap\MTRR, Hsap\NOS2, Hsap\NOS3, Hsap\NOS1" " embryonic stage , adult stage " antenna

"lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0082336 HM745 HM745 http://flybase.org/reports/FBgn0082336 gene - - - HM745 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024641 l(2)k12602 lethal (2) k12602 http://flybase.org/reports/FBgn0024641 - gene - - - "126/2, l(2)k12602" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0013502 l(1)PB2 lethal (1) PB2 http://flybase.org/reports/FBgn0013502 - gene - - - l(1)PB2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg" FBgn0024309 SM-20d Similar to rat Smooth Muscle-20 http://flybase.org/reports/FBgn0024309 - gene - - - "SM-20, SM-20d" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028950 CG15255 - http://flybase.org/reports/FBgn0028950 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026 neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "BG:BACR44L22.1, CG15255" "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG15255 11-Aug-17 DroID_v2017_08 "Drer\bmp1b, Drer\npsnl, Drer\c6ast1, Drer\si:ch73-40a17.3, Drer\he1a, Drer\mep1a.2, Drer\tll1, Drer\bmp1a, Drer\he1b, Drer\c6ast3, Drer\npsn, Drer\mep1b, Drer\LOC797085, Drer\c6ast4, Drer\tnfaip6, Drer\he2, Drer\mep1a.1, Drer\LOC100003133" - "Cele\nas-8, Cele\Y19D10A.6, Cele\nas-13, Cele\nas-6, Cele\nas-39, Cele\ZC116.3, Cele\nas-1, Cele\nas-15, Cele\nas-7, Cele\nas-14, Cele\nas-12, Cele\nas-2, Cele\nas-4" "Xtro\uvs.2, Xtro\bmp1, Xtro\mep1b, Xtro\LOC100489456, Xtro\tll1, Xtro\mep1a, Xtro\cubn, Xtro\LOC100492324, Xtro\tnfaip6, Xtro\accs, Xtro\tll2" "Mmus\Adgrg6, Mmus\Tll2, Mmus\Astl, Mmus\Tll1, Mmus\Cubn, Mmus\Bmp1, Mmus\Mep1a, Mmus\Mep1b, Mmus\Tnfaip6" "Hsap\BMP1, Hsap\ADGRG6, Hsap\TLL2, Hsap\TNFAIP6, Hsap\ASTL, Hsap\MEP1B, Hsap\TLL1, Hsap\MEP1A, Hsap\CUBN" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0000834 fs(1)M17 female sterile (1) M17 http://flybase.org/reports/FBgn0000834 - gene - - - fs(1)M17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "egg,maternal effect" FBgn0013602 l(3)B9-3-53 lethal (3) B9-3-53 http://flybase.org/reports/FBgn0013602 - gene - - - l(3)B9-3-53 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260636 l(3)72-73a - http://flybase.org/reports/FBgn0260636 gene - - - "l(3)72-73a, 72CDd, l(3)72CDd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060505 l(3)S104913a lethal (3) S104913a http://flybase.org/reports/FBgn0060505 gene - - - "1049/13, l(3)S104913a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264720 CR43988 - http://flybase.org/reports/FBgn0264720 non_protein_coding_gene - - - "CR43988, lincRNA.397" - CR43988 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264878 CR44069 - http://flybase.org/reports/FBgn0264878 non_protein_coding_gene - - - CR44069 - CR44069 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261632 CR42715 - http://flybase.org/reports/FBgn0261632 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR42715, CG42715, mdcds_11421, mdcds_11422" - CR42715 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259877 cid::His3 - http://flybase.org/reports/FBgn0259877 engineered_fusion_gene - - - cid::His3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051267 CG31267 - http://flybase.org/reports/FBgn0051267 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" - "SPH146, CG5240, CG31267" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG31267 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-33m11.8, Drer\prss59.2, Drer\zmp:0000001088, Drer\LOC103908930" - Cele\try-1 - "Mmus\Klk14, Mmus\Prss2, Mmus\Prss1, Mmus\2210010C04Rik, Mmus\Prss55, Mmus\Klk7, Mmus\Klk1b21, Mmus\1810009J06Rik, Mmus\Cfd, Mmus\Klk1b11, Mmus\Prss3, Mmus\Try5, Mmus\Try10, Mmus\Try4, Mmus\Gm5771" "Hsap\CFD, Hsap\KLK13, Hsap\KLK14" viable FBgn0039592 CG14062 - http://flybase.org/reports/FBgn0039592 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - "CG14062, LP23408p" IPR001604:DNA/RNA non-specific endonuclease CG14062 11-Aug-17 DroID_v2017_08 "Drer\LOC103910196, Drer\LOC100333474, Drer\endog" Scer\NUC1 Cele\cps-6 - Mmus\Endog Hsap\ENDOG viable FBgn0002882 mus106 mutagen-sensitive 106 http://flybase.org/reports/FBgn0002882 - gene - - - "mus(1)106, mus-106, mus106" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,DNA repair defective,recessive,radiation sensitive,female sterile" FBgn0001461 l(1)7Eb lethal (1) 7Eb http://flybase.org/reports/FBgn0001461 - gene - - - "JA4, l(1)7Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0267657 CR45995 - http://flybase.org/reports/FBgn0267657 non_protein_coding_gene - - - CR45995 - CR45995 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262565 CR43105 - http://flybase.org/reports/FBgn0262565 pseudogene_attribute - - - "CG43105, CR43105" - CR43105 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013763 Idgf6 Imaginal disc growth factor 6 http://flybase.org/reports/FBgn0013763 - protein_coding_gene chitinase activity ; GO:0004568 | NOT inferred from direct assay chitin binding ; GO:0008061 | inferred from direct assay chitinase activity ; GO:0004568 | non-traceable author statement imaginal disc growth factor receptor binding ; GO:0008084 | inferred from sequence or structural similarity with Idgf4 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from sequence or structural similarity with Idgf4 cuticle chitin catabolic process ; GO:0006036 | non-traceable author statement" extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG5210, chit, DS47, ds47, Cht13, DmDS47, Chit, Chit13, Idgf6, DmIDGF6, idgf6" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG5210 11-Aug-17 DroID_v2017_08 "Drer\chia.5, Drer\ovgp1, Drer\chia.6, Drer\chia.4, Drer\chia.3, Drer\si:ch211-226m16.2, Drer\chia.2" Scer\CTS2 "Cele\chil-12, Cele\chil-18, Cele\chil-4, Cele\chil-8, Cele\chil-15, Cele\chil-5, Cele\chil-16, Cele\chil-22, Cele\lmd-4, Cele\lmd-5, Cele\chil-11, Cele\T19H5.6, Cele\chil-23, Cele\chil-6, Cele\chil-2, Cele\chil-17, Cele\chil-19, Cele\cht-2, Cele\chil-3, Cele\chil-24, Cele\chil-25, Cele\chil-7, Cele\chil-20, Cele\chil-13" "Xtro\ctbs, Xtro\chit1, Xtro\chia, Xtro\LOC548945" "Mmus\Chit1, Mmus\Chia1, Mmus\Chil3, Mmus\Chil1, Mmus\Ctbs, Mmus\Ovgp1, Mmus\Chil4, Mmus\Chil5, Mmus\Chil6" "Hsap\CHIT1, Hsap\CHI3L2, Hsap\CHIA, Hsap\OVGP1, Hsap\CHI3L1" " larval stage , embryonic stage&&larval stage , adult stage | male , adult stage | female " " embryonic/larval fat body

, hemolymph

" " larval stage , embryonic stage -- adult stage " " embryonic/larval fat body

, hemolymph

" viable DRSC07360 K -0.016641266 0.56892805 -0.172799061 0.032153275 -1.558531472 0.189659516 FBgn0086389 BG01803 - http://flybase.org/reports/FBgn0086389 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01803 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0032486 mRF1 mitochondrial translation release factor 1 http://flybase.org/reports/FBgn0032486 protein_coding_gene "translation release factor activity, codon specific ; GO:0016149 | inferred from sequence or structural similarity with UniProtKB:O75570" translational termination ; GO:0006415 | inferred from sequence or structural similarity with UniProtKB:O75570 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O75570 "mRF1, CG5705" "IPR000352:Peptide chain release factor class I/class II, IPR005139:Peptide chain release factor" CG5705 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-275j6.5, Drer\mtrf1, Drer\mtrf1l" Scer\MRF1 Cele\W03F8.3 "Xtro\mtrf1, Xtro\taf8, Xtro\mtrf1l" "Mmus\Mtrf1l, Mmus\Taf8, Mmus\Mtrf1" "Hsap\MTRF1, Hsap\MTRF1L, Hsap\C12orf65, Hsap\TAF8" viable FBgn0025342 anon-58Fa anon-58Fa http://flybase.org/reports/FBgn0025342 - gene - - - "K3, anon-58Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044118 E(rst)B94 E(rst)B94 http://flybase.org/reports/FBgn0044118 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B94, E(rst)B94" - - 11-Aug-17 DroID_v2017_08 - - - - - - "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0267183 CR45623 - http://flybase.org/reports/FBgn0267183 non_protein_coding_gene - - - CR45623 - CR45623 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016714 Reg-19 Rhythmically expressed gene 19 http://flybase.org/reports/FBgn0016714 - gene - - - "Dreg-19, Reg-19" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , embryonic stage | late " adult head

FBgn0004927 l(3)dco2 lethal (3) discs overgrown 2 http://flybase.org/reports/FBgn0004927 - gene - - - "l(3)dco-2, l(3)dco2" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013736 stld stalled http://flybase.org/reports/FBgn0013736 - gene - grooming behavior ; GO:0007625 | inferred from mutant phenotype - stld - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive" FBgn0065801 l(2)SH0408 lethal (2) SH0408 http://flybase.org/reports/FBgn0065801 gene - - - "l(2)SH0408, l(2)SH2 0408" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046634 anon-38E.18 anon-38E.18 http://flybase.org/reports/FBgn0046634 gene - - - "38E.18, anon-38E.18" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262451 ban bantam http://flybase.org/reports/FBgn0262451 miRNA_gene mRNA 3'-UTR binding ; GO:0003730 | traceable author statement regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | traceable author statement positive regulation of growth ; GO:0045927 | traceable author statement miRNA mediated inhibition of translation ; GO:0035278 | traceable author statement cell growth ; GO:0016049 | traceable author statement negative regulation of translation ; GO:0017148 | traceable author statement gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype inferred from direct assay regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from direct assay regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype regulation of apoptotic signaling pathway ; GO:2001233 | inferred from genetic interaction with hpo regulation of cell proliferation ; GO:0042127 | inferred from genetic interaction with hpo eye development ; GO:0001654 | inferred from genetic interaction with hpo hippo signaling ; GO:0035329 | inferred from physical interaction with yki decapentaplegic signaling pathway ; GO:0008101 | inferred from physical interaction with Mad positive regulation of growth ; GO:0045927 | inferred from mutant phenotype formation of a compartment boundary ; GO:0060288 | inferred from mutant phenotype dendrite regeneration ; GO:0031104 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with hid AND inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | traceable author statement cellular response to X-ray ; GO:0071481 | inferred from direct assay positive regulation of stem cell proliferation ; GO:2000648 | inferred from mutant phenotype hippo signaling ; GO:0035329 | inferred from genetic interaction with yki inferred from genetic interaction with sav muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "ban, dme-bantam, CR43018, bantam, CR33559, cot, EP3208, miR-ban" - CR43018 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage -- adult stage , larval stage " " organism

, brain

restricted , dorsal mesothoracic disc

" FBgn0025120 su(RpII140[Z36])S8 su(RpII140[Z36])S8 http://flybase.org/reports/FBgn0025120 - gene - - - "Z36[S8], su(RpII140[Z36])S8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041140 l(2)44Da lethal (2) 44Da http://flybase.org/reports/FBgn0041140 gene - - - l(2)44Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0001115 gm gleam http://flybase.org/reports/FBgn0001115 - gene - - - gm - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced" "eye,ommatidium,interommatidial bristle" FBgn0014201 l(1)16Fh lethal (1) 16Fh http://flybase.org/reports/FBgn0014201 - gene - - - "HL-XI, l(1)16Fh" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038325 Atg4b Autophagy-related 4b http://flybase.org/reports/FBgn0038325 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity with SGD:S000005167 autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 nucleophagy ; GO:0044804 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 protein targeting to membrane ; GO:0006612 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 C-terminal protein lipidation ; GO:0006501 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 autophagy ; GO:0006914 | inferred from sequence or structural similarity with SGD:S000005167 mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 protein delipidation ; GO:0051697 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 cytosol ; GO:0005829 | inferred from sequence or structural similarity with SGD:S000005167 "DmAtg4-like, Atg4b, CG6194, Atg4, APG4, AUT2, atg4" IPR005078:Peptidase C54 CG6194 11-Aug-17 DroID_v2017_08 "Drer\atg4da, Drer\atg4b, Drer\atg4a, Drer\atg4db, Drer\atg4c" Scer\ATG4 "Cele\atg-4.2, Cele\atg-4.1" "Xtro\atg4a, Xtro\atg4b, Xtro\atg4c, Xtro\atg4d" "Mmus\Atg4d, Mmus\Atg4c, Mmus\Atg4b, Mmus\Atg4a" "Hsap\ATG4A, Hsap\ATG4D, Hsap\ATG4B, Hsap\ATG4C" pupal stage salivary gland

"viable,visible,fertile" "chaeta,supernumerary,trichogen cell" FBgn0039710 dgt1 dim gamma-tubulin 1 http://flybase.org/reports/FBgn0039710 protein_coding_gene histone acetyltransferase activity (H4-K8 specific) ; GO:0043996 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001003176 histone acetyltransferase activity (H4-K5 specific) ; GO:0043995 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001003176 histone acetyltransferase activity (H4-K16 specific) ; GO:0046972 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001003176 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs neurogenesis ; GO:0022008 | inferred from mutant phenotype NSL complex ; GO:0044545 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG18041, NSL2, Dgt1, dgt1" "IPR025927:Potential DNA-binding domain, IPR026316:KAT8 regulatory NSL complex subunit 2" CG18041 11-Aug-17 DroID_v2017_08 "Drer\kansl2, Drer\ino80db" - Cele\ins-33 Xtro\kansl2 "Mmus\Kansl2, Mmus\Ino80d" "Hsap\KANSL2, Hsap\INO80D" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC15301 E -0.546845495 -0.339042802 -0.497507385 -3.34504605 -0.951560735 -1.015911756 FBgn0035149 MED30 Mediator complex subunit 30 http://flybase.org/reports/FBgn0035149 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | contributes_to inferred by curator from GO:0016592 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 inferred from physical interaction with UniProtKB:Q9VEC1 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred by curator from GO:0016592 nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from direct assay "MED30, Med30, Trap25, CG17183, Med11/TRAP25, dMED20, dTRAP25, Med20, med30" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR021019:Mediator complex, subunit Med30, metazoa" CG17183 11-Aug-17 DroID_v2017_08 "Drer\zgc:114119, Drer\med30" - - Xtro\med30 Mmus\Med30 Hsap\MED30 "viable,visible" "trichogen cell,tormogen cell" DRSC30026 K 1.396496184 1.619990061 FBgn0039780 PH4alphaNE1 prolyl-4-hydroxylase-alpha NE1 http://flybase.org/reports/FBgn0039780 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG9728, PH4alphaNE1" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG9728 11-Aug-17 DroID_v2017_08 "Drer\p4ha2, Drer\p4ha3, Drer\p4ha1a, Drer\p4ha1b, Drer\zgc:158254, Drer\p4htm, Drer\zgc:152670" - "Cele\dpy-18, Cele\C14E2.4, Cele\phy-2, Cele\phy-3, Cele\phy-4, Cele\Y43F8B.19" "Xtro\p4ha3, Xtro\p4ha1, Xtro\p4ha2" "Mmus\P4ha1, Mmus\P4htm, Mmus\P4ha3, Mmus\P4ha2" "Hsap\P4HTM, Hsap\P4HA3, Hsap\P4HA2, Hsap\P4HA1" viable FBgn0036467 CG12310 - http://flybase.org/reports/FBgn0036467 protein_coding_gene - - - "BcDNA:RE02926, CG12310, chr3L:15015907..15016009" - CG12310 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001568 soz sozzled http://flybase.org/reports/FBgn0001568 - gene - - - "EA41, A72, l(1)20Bb, l(1)HM41, soz" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,viable" FBgn0005001 cu-X curled on X http://flybase.org/reports/FBgn0005001 - gene - - - cu-X - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male" "wing,male" FBgn0283473 S6KL S6 Kinase Like http://flybase.org/reports/FBgn0283473 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000682064" protein phosphorylation ; GO:0006468 | non-traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 "Pk17E, S6KL, BIN4, Bin4, CG7001, bin4, 3-10, Pk?4, pk17e, BcdK, PK17E" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain" CG7001 11-Aug-17 DroID_v2017_08 "Drer\sgk494b, Drer\rps6kb1a, Drer\prkcda, Drer\pkn1b, Drer\prkchb, Drer\prkca, Drer\prkcha, Drer\rps6kb1b, Drer\pkn2, Drer\prkcg, Drer\prkcea, Drer\prkceb, Drer\prkcbb, Drer\pkn1a, Drer\sgk494a, Drer\prkcq" "Scer\YPK3, Scer\RIM15, Scer\PKC1, Scer\DBF2, Scer\DBF20" "Cele\F31E3.2, Cele\F28C10.3, Cele\R04A9.7, Cele\rsks-1" "Xtro\pkn3, Xtro\prkcq, Xtro\prkcd, Xtro\gpha2, Xtro\tnfrsf1a, Xtro\LOC100493742, Xtro\prkcb, Xtro\prkce, Xtro\prkcg, Xtro\prkch, Xtro\pkn1" "Mmus\Pkn2, Mmus\BC030499, Mmus\Rps6kb2, Mmus\Prkcq, Mmus\Prkcd, Mmus\Prkch, Mmus\Prkca, Mmus\Rps6kb1, Mmus\Prkcg, Mmus\Prkce, Mmus\Pkn1, Mmus\Pkn3, Mmus\Prkcb" "Hsap\PRKCQ, Hsap\PKN3, Hsap\PKN2, Hsap\PKN1, Hsap\PRKCA, Hsap\PRKCD, Hsap\RPS6KB1, Hsap\RPS6KB2, Hsap\PRKCB, Hsap\SGK494, Hsap\PRKCG, Hsap\PRKCH, Hsap\PRKCE" "viable,fertile,neuroanatomy defective" anterior fascicle & synapse DRSC23147 K -0.728183635 -0.183412265 -0.101875161 0.511737199 -2.874983619 0.361835384 FBgn0051244 CG31244 - http://flybase.org/reports/FBgn0051244 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000283242 "CG18491, CG31244" "IPR002876:Transcriptional regulator TACO1-like, IPR029072:YebC-like" CG31244 11-Aug-17 DroID_v2017_08 "Drer\taco1, Drer\ino80, Drer\LOC100534805" "Scer\YGR021W, Scer\SWR1, Scer\INO80" Cele\taco-1 Xtro\taco1 "Mmus\Ino80, Mmus\Taco1" "Hsap\INO80, Hsap\TACO1" FBgn0263215 CR43385 - http://flybase.org/reports/FBgn0263215 pseudogene_attribute - - - CR43385 - CR43385 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024879 l(2)52Fb lethal (2) 52Fb http://flybase.org/reports/FBgn0024879 - gene - - - "D2.33, l(2)52Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259318 EP-64 - http://flybase.org/reports/FBgn0259318 gene - - - EP-64 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta,ectopic" FBgn0262771 Su(E1)-E - http://flybase.org/reports/FBgn0262771 gene - - - Su(E1)-E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261983 l(2)gd1 lethal (2) giant discs 1 http://flybase.org/reports/FBgn0261983 protein_coding_gene "phospholipid binding ; GO:0005543 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000317389" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000317389 sensory organ precursor cell division ; GO:0045035 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype multivesicular body organization ; GO:0036257 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000317389 cytoplasm ; GO:0005737 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "lgd, l(2)gd1, CG4713, l(2)gd, l(2)giant disc, gd, l[[2]]gd, l(2)SH0495, l(2)SH2 0495, SH495" "IPR006608:Domain of unknown function DM14, IPR000008:C2 domain" CG4713 11-Aug-17 DroID_v2017_08 "Drer\cc2d1b, Drer\cc2d1a" - Cele\Y37H9A.3 "Xtro\cc2d1b, Xtro\cc2d1a" "Mmus\Cc2d1b, Mmus\Cc2d1a" "Hsap\CC2D1A, Hsap\CC2D1B" FBgn0263529 mir-4977 mir-4977 stem loop http://flybase.org/reports/FBgn0263529 miRNA_gene - - - "mir-4977, dme-mir-4977, CR43514" - CR43514 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016910 l(3)X4 lethal (3) X4 http://flybase.org/reports/FBgn0016910 - gene - - - "X4, l(3)X4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020366 anon-10Ea anon-10Ea http://flybase.org/reports/FBgn0020366 - gene - - - "9H9, anon-10Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265997 CR44772 - http://flybase.org/reports/FBgn0265997 non_protein_coding_gene - - - "CR44772, lincRNA.19" - CR44772 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266901 CR45361 - http://flybase.org/reports/FBgn0266901 non_protein_coding_gene - - - "CR45361, pri-mir-1" - CR45361 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027574 CG5815 - http://flybase.org/reports/FBgn0027574 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 phospholipase D activity ; GO:0004630 | inferred from electronic annotation with InterPro:IPR016555 biological_process ; GO:0008150 | no biological data available inositol lipid-mediated signaling ; GO:0048017 | inferred from electronic annotation with InterPro:IPR016555 phosphatidic acid biosynthetic process ; GO:0006654 | inferred from electronic annotation with InterPro:IPR016555 cellular_component ; GO:0005575 | no biological data available "BcDNA:GH07089, BcDNA:GH07346, CG5815, Spt2" "IPR013256:Chromatin SPT2, IPR016555:Phospholipase D1/D2, IPR001683:Phox homologous domain, IPR011993:PH domain-like, IPR025202:Phospholipase D-like domain, IPR001736:Phospholipase D/Transphosphatidylase, IPR015679:Phospholipase D family" CG5815 11-Aug-17 DroID_v2017_08 "Drer\pld2, Drer\si:ch211-168k14.2, Drer\spty2d1, Drer\pld1b" - - "Xtro\pld2, Xtro\pld1, Xtro\spty2d1" "Mmus\Pld2, Mmus\Spty2d1" "Hsap\PLD2, Hsap\SPTY2D1" viable FBgn0283440 solo sisters on the loose http://flybase.org/reports/FBgn0283440 protein_coding_gene SMC family protein binding ; GO:0043221 | inferred from physical interaction with SMC1 "meiotic sister chromatid cohesion, centromeric ; GO:0051754 | inferred from mutant phenotype synaptonemal complex organization ; GO:0070193 | inferred from mutant phenotype cohesin loading ; GO:0071921 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype" "chromosome, centromeric region ; GO:0000775 | inferred from direct assay synaptonemal complex ; GO:0000795 | colocalizes_with inferred from direct assay" "solo, CG46282, BG:DS00929.15, CG43081, cgt, pf7, CG33678, fs(2)ltoRJ36, SOLO" - CG46282 11-Aug-17 DroID_v2017_08 "Drer\ddx3b, Drer\ddx3a, Drer\ddx4" "Scer\MRH4, Scer\DBP1, Scer\DED1" - Xtro\ddx3x "Mmus\Ddx3y, Mmus\Ddx4, Mmus\Ddx3x, Mmus\D1Pas1" "Hsap\DDX3Y, Hsap\DDX3X, Hsap\DDX4" "viable,female sterile" FBgn0046651 anon-38D.13 anon-38D.13 http://flybase.org/reports/FBgn0046651 gene - - - "38D.13, anon-38D.13" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045845 mdg1\sORF2 mdg1 element sORF2 http://flybase.org/reports/FBgn0045845 transposable_element_gene - - - "sORF, mdg1\sORF2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002833 ms(2)E12 male sterile (2) E12 http://flybase.org/reports/FBgn0002833 - gene - - - "ms2.12, ms(2)2.12, ms(2)E12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0037377 CG1218 - http://flybase.org/reports/FBgn0037377 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from direct assay poly-ADP-D-ribose binding ; GO:0072572 | inferred from direct assay - - CG1218 "IPR019361:Histone PARylation factor 1, IPR019406:Zinc finger, C2H2, APLF-like" CG1218 11-Aug-17 DroID_v2017_08 Drer\zgc:101819 - Cele\JC8.7 Xtro\c4orf27 Mmus\Hpf1 Hsap\HPF1 viable FBgn0022314 l(1)D47.6 lethal (1) D47.6 http://flybase.org/reports/FBgn0022314 - gene - - - "D47.6, l(1)D47.6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053426 5SrRNA:CR33426 5SrRNA:CR33426 http://flybase.org/reports/FBgn0053426 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33426, 5SrRNA:CR33426" - CR33426 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050134 CR30134 - http://flybase.org/reports/FBgn0050134 non_protein_coding_gene - - - CR30134 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046873 Pif2 PFTAIRE-interacting factor 2 http://flybase.org/reports/FBgn0046873 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Eip63E biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "PIF-2, bs20e01.y1, NEST:bs19e11, NEST:bs25a03, NEST:bs35g11, NEST:bs20e01, NEST:bs18a02, CG31483, BcDNA:AT26658, Pif2, pif2" - CG31483 11-Aug-17 DroID_v2017_08 - - Cele\Y39G8B.7 - "Mmus\Krtap4-13, Mmus\Gm11563, Mmus\Krtap4-2, Mmus\Krtap4-1, Mmus\Gm11554, Mmus\Krtap1-3" "Hsap\KRTAP5-9, Hsap\KRTAP9-3, Hsap\KRTAP4-4, Hsap\KRTAP4-2, Hsap\KRTAP9-4, Hsap\KRTAP9-6, Hsap\KRTAP4-5" FBgn0265306 CR44279 - http://flybase.org/reports/FBgn0265306 non_protein_coding_gene - - - CR44279 - CR44279 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027868 Nup107 Nucleoporin 107kD http://flybase.org/reports/FBgn0027868 - protein_coding_gene nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000313483 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with HGNC:29914 structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000313483 "mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000313483 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery ; GO:0000973 | inferred from biological aspect of ancestor with PANTHER:PTN000313483 regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000313483 mRNA export from nucleus ; GO:0006406 | inferred from sequence or structural similarity with HGNC:29914 SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype" nuclear envelope ; GO:0005635 | inferred from direct assay nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with HGNC:29914 kinetochore ; GO:0000776 | NOT inferred from direct assay nuclear pore outer ring ; GO:0031080 | inferred from biological aspect of ancestor with PANTHER:PTN000313483 "CG6743, BcDNA:LD18761, Nup107, Nup170, nup107, dmNup107, Nup 107" IPR007252:Nuclear pore protein 84/107 CG6743 11-Aug-17 DroID_v2017_08 Drer\nup107 Scer\NUP84 Cele\npp-5 Xtro\nup107 Mmus\Nup107 Hsap\NUP107 "lethal,recessive" DRSC01999 I -1.773437527 -0.484563148 1.461795437 -0.705786728 -0.771244062 -0.04787634 FBgn0000296 Cg67C Collagen-like 67C http://flybase.net/reports/FBgn0000296.html gene "DCg20, DCg16, Cg11, DCg22, DCg17, DCg11" 11-Aug-17 DroID_v2017_08 FBgn0028858 CG10839 - http://flybase.org/reports/FBgn0028858 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from sequence or structural similarity "BG:DS07486.2, CG10839" "IPR025875:Leucine rich repeat 4, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG10839 11-Aug-17 DroID_v2017_08 "Drer\lrrc9, Drer\cep97, Drer\lrguk, Drer\ppp1r7, Drer\lrrc23, Drer\dnal1, Drer\lrriq1, Drer\lrrc6, Drer\lrrcc1, Drer\drc3, Drer\si:ch211-103e16.5, Drer\si:dkey-267j14.7, Drer\lrrc61" "Scer\NUD1, Scer\SDS22" - "Xtro\ppp1r7, Xtro\lrrc9, Xtro\lrrc56, Xtro\lrrc49, Xtro\lrrc6, Xtro\drc3, Xtro\lrrcc1, Xtro\lrrc23, Xtro\dnal1, Xtro\cep97" "Mmus\Lrrc43, Mmus\Lrrc9, Mmus\Lrrc6, Mmus\Lrguk, Mmus\Lrrcc1, Mmus\Lrrc23, Mmus\Dnal1, Mmus\Cep97, Mmus\Lrrc56, Mmus\Lrrc61, Mmus\Lrriq3, Mmus\Ppp1r7, Mmus\Lrriq1, Mmus\Lrrc46, Mmus\Lrrc49, Mmus\Lrrc48" "Hsap\LRRC46, Hsap\PPP1R7, Hsap\DRC3, Hsap\LRRC56, Hsap\LRRIQ3, Hsap\LRRCC1, Hsap\LRGUK, Hsap\LRRC49, Hsap\DNAL1, Hsap\LRRC23, Hsap\LRRC43, Hsap\CEP97, Hsap\LRRC6, Hsap\LRRC61, Hsap\LRRIQ1" viable FBgn0065219 l(2)SH2234 lethal (2) SH2234 http://flybase.org/reports/FBgn0065219 gene - - - "l(2)SH2234, l(2)SH2 2234" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015521 RpS21 Ribosomal protein S21 http://flybase.org/reports/FBgn0015521 "FBgn0010545, FBgn0014276" protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement ribosome binding ; GO:0043022 | inferred from physical interaction with UniProtKB:P38979 structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001931, InterPro:IPR018279 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000461 | inferred from biological aspect of ancestor with PANTHER:PTN000047682 lymph gland development ; GO:0048542 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000047682 regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype" cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay "RpS21, rpS21, l(2)168/14, oho23, l(2)k16814, l(2)03575, CG2986, oho23B, M(2)23B" "IPR018279:Ribosomal protein S21e, conserved site, IPR001931:Ribosomal protein S21e" CG2986 11-Aug-17 DroID_v2017_08 Drer\rps21 "Scer\RPS21B, Scer\RPS21A" Cele\rps-21 Xtro\rps21 Mmus\Rps21 Hsap\RPS21 embryonic stage -- adult stage embryonic stage -- adult stage "lethal,recessive,wild-type,developmental rate defective,dominant,hyperplasia,visible,short lived,lethal - all die before end of larval stage,some die during larval stage,Minute" "embryonic/larval lymph gland,imaginal disc,ventral thoracic disc,wing disc,adult head,primary lobe of embryonic/larval lymph gland,embryonic/larval hemocyte,macrochaeta,scutum,embryonic/larval brain" DRSC00833 IEK -0.351015164 -1.704300758 -0.942362025 -3.302513483 -0.003517076 2.205533813 FBgn0032740 CG15172 - http://flybase.org/reports/FBgn0032740 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15172 - CG15172 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015615 SMC3 Structural maintenance of chromosomes 3 http://flybase.org/reports/FBgn0015615 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR010935 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with HGNC:2468 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with MGI:MGI:1339795 mitotic sister chromatid cohesion ; GO:0007064 | inferred from electronic annotation with InterPro:IPR029685 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR029685 establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cohesin complex ; GO:0008278 | inferred from direct assay cohesin complex ; GO:0008278 | non-traceable author statement "SMC3, Smc3, DmSMC3, cap, DmSMC3/Cap, CG9802, dCAP, Cap, dSMC3, CAP" "IPR003395:RecF/RecN/SMC, N-terminal, IPR010935:SMCs flexible hinge, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024704:Structural maintenance of chromosomes protein, IPR029685:Structural maintenance of chromosomes protein 3" CG9802 11-Aug-17 DroID_v2017_08 Drer\smc3 Scer\SMC3 Cele\smc-3 Xtro\smc3 Mmus\Smc3 Hsap\SMC3 larval stage&&adult stage "planar polarity defective,somatic clone,visible,cell size defective,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,partially lethal - majority die" "wing hair,wing margin,somatic clone,wing vein,ectopic,wing,ganglion mother cell,trichogen cell,supernumerary,mesothoracic tergum" DRSC20227 K 0.863071539 0.302431162 -0.508684499 0.874764233 1.843428084 1.709508332 FBgn0259522 GG01017 - http://flybase.org/reports/FBgn0259522 gene - - - GG01017 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,antennal segment,arista" FBgn0243513 cnir cornichon related http://flybase.org/reports/FBgn0243513 protein_coding_gene - vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR003377 "cnir, Cnir, CG17262" IPR003377:Cornichon CG17262 11-Aug-17 DroID_v2017_08 "Drer\cnih2, Drer\cnih3, Drer\cnih1, Drer\cnih4" "Scer\ERV14, Scer\ERV15" Cele\cni-1 "Xtro\cnih2, Xtro\cnih4, Xtro\cnih1" "Mmus\Cnih2, Mmus\Cnih3, Mmus\Cnih1, Mmus\Cnih4" "Hsap\CNIH2, Hsap\CNIH4, Hsap\CNIH3, Hsap\CNIH1" FBgn0003205 Ras85D Ras oncogene at 85D http://flybase.org/reports/FBgn0003205 "FBgn0011008, FBgn0011548" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Rgl GTPase activity ; GO:0003924 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with spri" "imaginal disc-derived wing vein morphogenesis=0008586 |...<> dorsal closure, amnioserosa morphology change=0046664 | NOT inferred from<> cell fate specification=0001708 | traceable author statement <> peripheral nervous system development=0007422 |...<> ovarian follicle cell development=0030707 | traceable author statement <> compound eye development=0048749 |...<> chorion-containing eggshell pattern formation=0030381 |...<> cellular response to starvation=0009267 |...<> stem cell fate commitment=0048865 |...<> regulation of cell growth=0001558 | traceable author statement <> negative regulation of compound eye retinal cell programmed cell death=0046673 |...<> stem cell differentiation=0048863 |...<> negative regulation of macroautophagy=0016242 |...<> Malpighian tubule development=0072002 |...<> negative regulation of autophagy=0010507 |...<> regulation of multicellular organism growth=0040014 |...<> negative regulation of apoptotic process=0043066 |...<> tracheal outgrowth, open tracheal system=0007426 |...<> imaginal disc-derived wing morphogenesis=0007476 |...<> border follicle cell migration=0007298 | traceable author statement <> cell growth=0016049 | traceable author statement <> positive regulation of MAPK cascade=0043410 |...<> regulation of growth=0040008 | traceable author statement <> establishment or maintenance of apical/basal cell polarity=0035088 |...<> negative regulation of compound eye retinal cell programmed cell death=0046673 | traceable author statement <> positive regulation of cell growth=0030307 | traceable author statement <> wing disc morphogenesis=0007472 |...<> anterior/posterior axis specification, embryo=0008595 | traceable author statement <> positive regulation of cell size=0045793 |...<> regulation of apoptotic process=0042981 |...<> gastrulation=0007369 |...<> dorsal closure=0007391 | traceable author statement <> trachea development=0060438 |...<> intestinal stem cell homeostasis=0036335 |...<> determination of adult lifespan=0008340 |...<> positive regulation of cell proliferation=0008284 |...<> regulation of hemocyte differentiation=0045610 |...<> cell fate determination=0001709 |...<> primary branching, open tracheal system=0007428 | traceable author statement <> negative regulation of apoptotic process=0043066 | <> torso signaling pathway=0008293 | traceable author statement <> G1/S transition of mitotic cell cycle=0000082 | traceable author statement <> stem cell proliferation=0072089 |...<> regulation of cell size=0008361 |...<> metamorphosis=0007552 |...<> border follicle cell migration=0007298 |...<> protein import into nucleus=0006606 |... genetic interaction with rl <> photoreceptor cell morphogenesis=0008594 |...<> oocyte axis specification=0007309 |...<> eye-antennal disc morphogenesis=0007455 |...<> cell proliferation=0008283 |...<> heart development=0007507 | <> TORC1 signaling=0038202 |...<> sevenless signaling pathway=0045500 | traceable author statement <> hemocyte migration=0035099 |...<> negative regulation of apoptotic signaling pathway=2001234 |... genetic interaction with hid inferred from genetic interaction with rpr <> regulation of growth=0040008 |...inferred from genetic interaction with scrib <> positive regulation of photoreceptor cell differentiation=0046534 |...<> instar larval development=0002168 |... mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay "Ras, ras, RAS85D, RAS, RasV12, Ras1, dRas, D-Ras1, RTK, dRas1, ras1, D-Ras, Dras1, dras1, Dm Ras1, S35097, DRas85D/Ras, Dras, DRAS1, Ras-1, DRas, dRAS1, ras 1, EK3-4, ras85D, ras85B, RAS1, RasI, l(3)06677, D-ras1, Dras85D, E(faf), E(sev)3C, Su(tor)3-2, p21[Ras1], D-ras-1, Dmras85D, l(3)s1747, fs(3)05703, CG9375, C-ras1, Ras85D, Ras1/RAs85D, EC3-3, Ras85, dRas85D, Ras[V12], Ras 85D, P08646, Ras85DNt, Ras185D" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR020849:Small GTPase superfamily, Ras type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9375 11-Aug-17 DroID_v2017_08 "Drer\zgc:153845, Drer\rsg1, Drer\zgc:171704, Drer\si:dkey-27j5.5, Drer\nras, Drer\LOC103909873, Drer\gem, Drer\rit1, Drer\rras2, Drer\rasl12, Drer\si:ch73-116o1.2, Drer\zgc:110699, Drer\hrasa, Drer\mras, Drer\rap1aa, Drer\rasl11a, Drer\ralbb, Drer\rerglb, Drer\rap1b, Drer\rrad, Drer\rap1ab, Drer\diras1b, Drer\zgc:64022, Drer\hrasb, Drer\diras1a, Drer\rem2, Drer\ralab, Drer\kras, Drer\rap2b, Drer\ralaa, Drer\rheb, Drer\rap2c, Drer\rergla, Drer\si:dkeyp-59c12.1, Drer\zgc:55558, Drer\rasl11b, Drer\ralba, Drer\diras2, Drer\rap2ab, Drer\rhebl1, Drer\rem1, Drer\zgc:152698, Drer\rasd1, Drer\rasl10a, Drer\zgc:114118, Drer\rras, Drer\LOC100332969" "Scer\RHB1, Scer\RAS2, Scer\RAS1, Scer\RSR1" "Cele\ras-1, Cele\C44B7.12, Cele\let-60, Cele\rap-1, Cele\ral-1" "Xtro\rap1b, Xtro\LOC733456, Xtro\nras, Xtro\adal, Xtro\diras1, Xtro\rit1, Xtro\rergl, Xtro\kras, Xtro\rheb, Xtro\hras, Xtro\rasl10a, Xtro\rap2a, Xtro\rem2, Xtro\ralb, Xtro\rras, Xtro\gem, Xtro\rap2b, Xtro\rala, Xtro\diras2, Xtro\rasd2, Xtro\rap2c, Xtro\LOC100485959, Xtro\ras-dva, Xtro\rhebl1, Xtro\diras3, Xtro\rem1, Xtro\rap1a, Xtro\rsg1, Xtro\rasd1, Xtro\rrad, Xtro\rasl11b, Xtro\rerg" "Mmus\Rap1b, Mmus\Rit2, Mmus\Rsg1, Mmus\Rap2b, Mmus\Rap2a, Mmus\Adal, Mmus\Rergl, Mmus\Rerg, Mmus\Rras, Mmus\Rras2, Mmus\Kras, Mmus\Rasl10a, Mmus\Nras, Mmus\Rap1a, Mmus\Hras, Mmus\Rasd2, Mmus\Rit1, Mmus\Rasd1, Mmus\Rheb, Mmus\Diras1, Mmus\Gem, Mmus\Gm266, Mmus\Eras, Mmus\Rasl10b, Mmus\Mras, Mmus\Rem1, Mmus\Diras2, Mmus\Rrad, Mmus\Rala, Mmus\Rap2c, Mmus\Rasl11b, Mmus\Rhebl1, Mmus\Rem2, Mmus\Ralb, Mmus\Rasl12, Mmus\Rasl11a" "Hsap\RHEB, Hsap\REM1, Hsap\DIRAS1, Hsap\RASL11B, Hsap\RASD2, Hsap\KRAS, Hsap\RERG, Hsap\RERGL, Hsap\RRAS, Hsap\RAP1B, Hsap\RSG1, Hsap\ERAS, Hsap\RASL11A, Hsap\NRAS, Hsap\RIT1, Hsap\DIRAS3, Hsap\RASL12, Hsap\RALA, Hsap\RALB, Hsap\REM2, Hsap\RAP1A, Hsap\RAP2B, Hsap\RAP2C, Hsap\MRAS, Hsap\HRAS, Hsap\RASL10A, Hsap\RRAD, Hsap\RIT2, Hsap\DIRAS2, Hsap\RAP2A, Hsap\RRAS2, Hsap\GEM, Hsap\RHEBL1, Hsap\RASD1, Hsap\RASL10B" " embryonic stage , egg stage | unfertilized egg , embryonic stage | early , adult stage , adult stage && oogenesis stage , larval stage | third instar " " unfertilized egg

, thoracico-abdominal ganglion

, oocyte

, dorsal mesothoracic disc

, eye-antennal disc

, larval brain | restricted

, adult brain | resticted

, genital disc

" "increased cell size,partially lethal - majority die,recessive,female sterile,visible,neuroanatomy defective,viable,partially,lethal,dominant,decreased cell death,wild-type,cell polarity defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,increased cell death,hyperplasia,lethal - all die before end of P-stage,heat sensitive,some die during pharate adult stage,somatic clone,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,cell autonomous,cell non-autonomous,decreased cell size,decreased cell number,germline clone,terminal phenotype,small body,lethal - all die before end of pupal stage,some die during pupal stage,large body,developmental rate defective,temperature conditional,increased cell number,tumorigenic,conditional,cell size defective,learning defective,increased cell growth,short lived,RU486 conditional,cell death defective,some die during P-stage,majority die during P-stage,neoplasia,size defective,female semi-sterile" "eye disc,adult heart,adult heart muscle,myofilament,cardial cell,dorsal appendage,ommatidium,egg chamber,nurse cell,oocyte,ovary,chorion,head,female terminalia,male terminalia,abdominal segment,embryonic/first instar larval cuticle,type I bouton,germarium,spectrosome,egg,tergite,midgut,wing,photoreceptor cell,,eye,midline glial cell,posterior crossvein,wing vein,cone cell,pigment cell,filzkorper,embryonic head,border follicle cell,embryo,eye-antennal disc,secondary pigment cell,tertiary pigment cell,mesothoracic tibial bract,bract,macrochaeta,abdominal ventral monoscolopidial chordotonal organ,abdominal lateral pentascolopidial chordotonal organ,pericardial cell primordium,A1-7 ventral acute muscle 2,imaginal disc,pole cell,salivary gland common duct primordium,gastrula embryo,follicle cell,oocyte associated follicle cell,ommatidial precursor cluster,cyst progenitor cell,adult midgut precursor cell,adult Malpighian tubule,enterocyte,intestinal stem cell,adult head,wing disc,dorsal air sac primordium,ganglionic branch 1 |,germline stem cell,embryonic/larval somatic muscle,dorsal oblique muscle,pericardial cell,dorsal acute muscle,muscle founder cell,mesoderm,mitotic cell cycle,bi-omb-Gal4,hs.PB,interface glial cell,pCC neuron,dMP2 neuron,vMP2 neuron,morphogenetic furrow,anterior crossvein,embryonic/larval ganglionic branch,‘±Tub84B.PP,mesothoracic tergum,repo,peripheral glial cell |,motor neuron |,presumptive embryonic/larval peripheral nervous system,fascicle |,bouton,embryonic segment,tracheal branch primordium,fusion competent cell,embryonic hemocyte,adult gut,enteroblast of posterior adult midgut epithelium,embryonic/larval hemocyte,wing disc posterior compartment,adult midgut precursor cell |,embryonic/larval neuromuscular junction | larval stage,gastric caecum,embryonic/larval oenocyte,wing disc |,embryonic epidermis,GMR.PF,optic cartridge |,lamina,sensory mother cell,-C253,‘±Tub84B.PL,chaeta,coxa,sensillum trichodeum,arista,third segment of antenna,capitellum,haltere pedicel,gonopod thorn bristle,embryonic/larval tracheal system,embryonic/larval trachea,midgut constriction,abdominal dorsal adult muscle precursor cell,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,prothoracic gland,denticle,twi.2PE,melanotic mass,hemocyte,interommatidial bristle,rhabdomere,embryonic/larval salivary gland,wing margin,ventral nerve cord,embryonic cardioblast,wing hair,amnioserosa,embryo | dorsal closure stage,embryonic leading edge cell,embryonic/larval brain |,embryonic/larval brain,glial cell,adult brain,optic lobe,embryonic/larval peripheral nervous system |,embryonic/larval midgut,adult midgut precursor cell | prepupal stage P1" DRSC16814 IEK -2.053766822 -5.933335433 -2.961312249 -5.70836373 -3.474241308 -4.513458333 FBgn0263386 CG43438 - http://flybase.org/reports/FBgn0263386 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43438, lincRNA.111" - CG43438 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015896 anon-95EFb anon-95EFb http://flybase.org/reports/FBgn0015896 - gene - - - anon-95EFb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084005 CG41439 - http://flybase.org/reports/FBgn0084005 protein_coding_gene - - - CG41439 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261285 Ppcs Phosphopantothenoylcysteine synthetase http://flybase.org/reports/FBgn0261285 protein_coding_gene phosphopantothenate--cysteine ligase activity ; GO:0004632 | inferred from sequence alignment with AGI_LocusCode:AT1G12350 "actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype phospholipid homeostasis ; GO:0055091 | inferred from mutant phenotype cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype coenzyme A biosynthetic process ; GO:0015937 | inferred from sequence alignment with AGI_LocusCode:AT1G12350 ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype" - "Ppcs, CG5629, PPCS, dPPCS, GH03502, BcDNA:GH03502, anon-WO0118547.401" "IPR007085:DNA/pantothenate metabolism flavoprotein, C-terminal" CG5629 11-Aug-17 DroID_v2017_08 Drer\ppcs Scer\CAB2 Cele\Y71H2AM.6 Xtro\ppcs Mmus\Ppcs Hsap\PPCS FBgn0082923 snoRNA:Or-aca3 snoRNA:Or-aca3 http://flybase.org/reports/FBgn0082923 snoRNA_gene - - - "snoRNA:Or-aca3, DmOr_aca3 snoRNA, Or_aca3 snoRNA, DmOr_aca3, CR34617, Or-aca3, chr3R:23749517..23749792, snoRNA:Or-ACA3" - CR34617 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012058 Cdc27 Cell division cycle 27 http://flybase.org/reports/FBgn0012058 FBgn0024570 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred by curator from GO:0005680 "anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay condensed chromosome ; GO:0000793 | colocalizes_with inferred from direct assay anaphase-promoting complex ; GO:0005680 | inferred from physical interaction with APC7 "mks, cdc27, CDC27Dm, Dmcdc27, l(3)L7123, CG8610, Cdc27, CDC27, Apc3, APC3" "IPR013026:Tetratricopeptide repeat-containing domain, IPR011990:Tetratricopeptide-like helical domain, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1" CG8610 11-Aug-17 DroID_v2017_08 Drer\cdc27 Scer\CDC27 Cele\mat-1 Xtro\cdc27 "Mmus\Cdc27, Mmus\Ttc37" "Hsap\CDC27, Hsap\TTC37" "visible,lethal,recessive,partially lethal - majority die,female limited,female sterile,partially,sterile,short lived,mitotic cell cycle defective,lethal - all die before end of P-stage,some die during pharate adult stage,decreased cell number,somatic clone,increased cell death,neuroanatomy defective,some die during pupal stage" "wing,spindle & neuroblast,aster & neuroblast,chromosome & neuroblast,chromatin & neuroblast,mitotic metaphase & neuroblast,chromosome | supernumerary,eye,chaeta,mitotic cell cycle,mitosis & nuclear chromosome,spindle & neuroblast & larva,chromosome,chromatin,mitotic metaphase,condensed chromosome & neuroblast & larva,embryonic/larval brain,somatic clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC11112 IEK 3.114990628 -4.071975121 6.123000568 -6.573465093 -1.602426924 -2.155705423 FBgn0041229 Gr93a Gustatory receptor 93a http://flybase.org/reports/FBgn0041229 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement response to caffeine ; GO:0031000 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr93F1, CG13417, 93F.1, GR93F.1, Gr93a, GR93, GR93a" IPR013604:7TM chemoreceptor CG13417 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - "chemosensitive behavior defective,viable,fertile" FBgn0038084 beat-Vc beat-Vc http://flybase.org/reports/FBgn0038084 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic - "beat Vc, CG14390, beat-Vc, Beat-Vc" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG14390 11-Aug-17 DroID_v2017_08 "Drer\jam2b, Drer\f11r.2" - - - - Hsap\CADM2 viable FBgn0034366 Atg7 Autophagy-related 7 http://flybase.org/reports/FBgn0034366 protein_coding_gene Atg8 activating enzyme activity ; GO:0019779 | inferred from sequence or structural similarity with SGD:S000001214 Atg12 activating enzyme activity ; GO:0019778 | inferred from sequence or structural similarity with SGD:S000001214 ubiquitin activating enzyme activity ; GO:0004839 | NOT inferred from direct assay Atg8 activating enzyme activity ; GO:0019779 | inferred from direct assay oogenesis ; GO:0048477 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | NOT inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from sequence or structural similarity with UniProtKB:Q9D906 autophagosome assembly ; GO:0000045 | inferred from sequence or structural similarity with UniProtKB:Q9D906 protein modification by small protein conjugation ; GO:0032446 | inferred from sequence or structural similarity with SGD:S000001214 positive regulation of macroautophagy ; GO:0016239 | inferred from mutant phenotype protein modification by small protein conjugation ; GO:0032446 | inferred from direct assay protein lipidation ; GO:0006497 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from sequence or structural similarity with SGD:S000001214 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with UniProtKB:Q9D906 negative regulation of cell death ; GO:0060548 | inferred from sequence or structural similarity with UniProtKB:Q9D906 autophagy ; GO:0006914 | inferred from sequence or structural similarity with UniProtKB:Q9D906 autophagy ; GO:0006914 | inferred from mutant phenotype macroautophagy ; GO:0016236 | inferred from mutant phenotype regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype regulation of hemopoiesis ; GO:1903706 | inferred from sequence or structural similarity with UniProtKB:Q9D906 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype C-terminal protein lipidation ; GO:0006501 | inferred from sequence or structural similarity with SGD:S000001214 pre-autophagosomal structure ; GO:0000407 | inferred from sequence or structural similarity with SGD:S000001214 "Atg7, CG5489, atg7, atg-7, ATG7, dAtg7" "IPR000594:THIF-type NAD/FAD binding fold, IPR006285:Ubiquitin-like modifier-activating enzyme Atg7, IPR032197:Ubiquitin-like modifier-activating enzyme Atg7, N-terminal" CG5489 11-Aug-17 DroID_v2017_08 Drer\atg7 Scer\ATG7 Cele\atg-7 Xtro\atg7 Mmus\Atg7 Hsap\ATG7 pupal stage salivary gland

"viable,immune response defective,RU486 conditional,memory defective,progressive,decreased cell death,short lived,chemical sensitive,stress response defective,nutrition conditional,somatic clone" "major mitochondrial derivativenos.PG, nos.UTR.THsimVP16, otu.THsimVP16,intestinal stem cell,chemical conditional,autophagic vacuole & larval midgut,embryonic/larval midgut,adult brain,major mitochondrial derivative,embryonic/larval fat body,germarium region 2,nutrition conditional,female germline cyst,egg chamber,egg,somatic clone,germarium,rhabdomere" DRSC05741 IE -1.93654014 -1.692957226 -1.787479904 -0.913538235 -0.494455303 0.165497783 FBgn0003104 PL(3)sp-T2 Polygenic locus sternopleural T2 http://flybase.org/reports/FBgn0003104 - gene - - - "PL(3)sp[T2], 3b, PL(3)sp-T2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032857 CG10947 - http://flybase.org/reports/FBgn0032857 protein_coding_gene S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from sequence or structural similarity with SGD:S000002547 regulation of translation ; GO:0006417 | inferred from sequence or structural similarity with SGD:S000002547 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002547 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002547 "38C.42, CG10947" "IPR019410:Lysine methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG10947 11-Aug-17 DroID_v2017_08 Drer\si:ch73-54n14.2 - Cele\Y48E1C.1 Xtro\camkmt Mmus\Camkmt Hsap\CAMKMT viable FBgn0266569 CG42259 - http://flybase.org/reports/FBgn0266569 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with Hml hemolymph coagulation ; GO:0042381 | inferred from sequence or structural similarity with Hml extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Hml "CG42259, C, anon-1Ea" "IPR002919:Trypsin Inhibitor-like, cysteine rich domain" CG42259 11-Aug-17 DroID_v2017_08 - - "Cele\F36H9.4, Cele\C25E10.7, Cele\C25E10.8, Cele\T01D3.3, Cele\spi-1, Cele\swm-1, Cele\C10G8.4, Cele\Y26D4A.12, Cele\C53B7.2, Cele\F32D8.3, Cele\B0238.12, Cele\C25E10.10, Cele\K07A1.6" - - - FBgn0032993 CG18117 - http://flybase.org/reports/FBgn0032993 protein_coding_gene - - - CG18117 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262574 CG43114 - http://flybase.org/reports/FBgn0262574 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response ; GO:0006952 | inferred from electronic annotation with InterPro:IPR003614 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43114, MIP09856" "IPR003614:Knottin, scorpion toxin-like" CG43114 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266117 CR44843 - http://flybase.org/reports/FBgn0266117 non_protein_coding_gene - - - CR44843 - CR44843 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065714 l(2)SH0580 lethal (2) SH0580 http://flybase.org/reports/FBgn0065714 gene - - - l(2)SH0580 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067305 D11 D11 http://flybase.org/reports/FBgn0067305 gene - - - D11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable" FBgn0051316 CG31316 - http://flybase.org/reports/FBgn0051316 protein_coding_gene - - - "BcDNA:RH30043, CG31316" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051397 CG31397 - http://flybase.org/reports/FBgn0051397 protein_coding_gene - - - CG31397 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC12794 E 0.595782569 0.7106473 1.646060369 -0.994312779 -0.403439417 -0.497844953 FBgn0002155 l(2)mr lethal (2) with morula http://flybase.org/reports/FBgn0002155 - gene - - - "l(2)mr[2], l(2)mr" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265679 CR44486 - http://flybase.org/reports/FBgn0265679 non_protein_coding_gene - - - "lincRNA.184, CR44486" - CR44486 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060364 l(3)S138415a lethal (3) S138415a http://flybase.org/reports/FBgn0060364 gene - - - "1384/15, l(3)S138415a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004767 l(3)89Ef lethal (3) 89Ef http://flybase.org/reports/FBgn0004767 - gene - - - l(3)89Ef - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003578 Su(sc) Suppressor of scute http://flybase.org/reports/FBgn0003578 - gene - - - "sc-Inh-3, Ext-sct-3, Su(sc)" - - 11-Aug-17 DroID_v2017_08 - - - - - - macrochaeta FBgn0051408 CG31408 - http://flybase.org/reports/FBgn0051408 protein_coding_gene - - - CG31408 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023412 Ars-region21 Autonomous replicating sequence region 21 http://flybase.org/reports/FBgn0023412 - region - - - "dARS21, Ars-region21, Ars21" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033250 CG14762 - http://flybase.org/reports/FBgn0033250 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from biological aspect of ancestor with PANTHER:PTN000689992 - "CT34565, CG14762" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG14762 11-Aug-17 DroID_v2017_08 "Drer\slit3, Drer\lrfn1, Drer\lrfn5a, Drer\slitrk3b, Drer\lrfn4a, Drer\zmp:0000001073, Drer\lrfn2b, Drer\lrrn1, Drer\zgc:172282, Drer\lrfn4b, Drer\slit1a, Drer\lrfn5b, Drer\lrrn3, Drer\si:ch211-180f4.1, Drer\slit2, Drer\LOC100535105, Drer\lrrn2, Drer\lrrc15" - "Cele\sym-1, Cele\lron-1, Cele\pan-1, Cele\lron-12, Cele\slt-1, Cele\lron-2, Cele\let-4" "Xtro\lrfn1, Xtro\lrfn2, Xtro\lrfn3, Xtro\lrfn5, Xtro\lrrn1-like" "Mmus\Lrfn5, Mmus\Lrfn3, Mmus\Lrfn2, Mmus\Slit3, Mmus\Lrrn3, Mmus\Lrfn1, Mmus\Aspn, Mmus\Gp5, Mmus\Lrfn4, Mmus\Slit1, Mmus\Lrrn2, Mmus\Slit2, Mmus\Lrrn1" "Hsap\LRFN5, Hsap\GP5, Hsap\SLIT1, Hsap\LRRN1, Hsap\LRRN2, Hsap\SLIT3, Hsap\LRFN3, Hsap\RXFP2, Hsap\LRRN3, Hsap\LRFN4, Hsap\LRFN2, Hsap\ASPN, Hsap\LRFN1, Hsap\SLIT2" viable FBgn0265301 CR44274 - http://flybase.org/reports/FBgn0265301 non_protein_coding_gene - - - CR44274 - CR44274 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267914 CR46195 - http://flybase.org/reports/FBgn0267914 non_protein_coding_gene - - - CR46195 - CR46195 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030912 CG6023 - http://flybase.org/reports/FBgn0030912 protein_coding_gene - - - CG6023 - CG6023 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0011986 tRNA:Ser-AGA-2-5 transfer RNA:Serine-AGA 2-5 http://flybase.org/reports/FBgn0011986 "FBgn0011968, FBgn0011979, FBgn0052419, FBgn0060066" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "777-5, tRNA[Ser][[7]], tRNA[[7]][Ser], tRNA[Ser], AE002602.trna13-SerAGA, tRNA:S:AGA:AE002602, CR32419, tRNA:ser, tRNA:S, tRNA:S7, tRNA:ser7, tRNA:ser7:56D, tRNA:S7:56D, tRNA[[Ser]], chr3L.trna19-SerAGA, tRNA-Ser-AGA-2-5, tRNA:Ser-AGA-2-5, tRNA:S7:64D, UCU" - CR32419 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030031 CG2156 - http://flybase.org/reports/FBgn0030031 protein_coding_gene - - - CG2156 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060648 l(3)S083606b lethal (3) S083606b http://flybase.org/reports/FBgn0060648 gene - - - "0836/06, l(3)S083606b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025640 CG13369 - http://flybase.org/reports/FBgn0025640 - protein_coding_gene ribokinase activity ; GO:0004747 | inferred from sequence or structural similarity with SGD:S000000632 D-ribose metabolic process ; GO:0006014 | inferred from sequence or structural similarity with SGD:S000000632 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000632 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000632 "EG:115C2.1, CG13369" "IPR002139:Ribokinase/fructokinase, IPR002173:Carbohydrate/puine kinase, PfkB, conserved site, IPR011611:Carbohydrate kinase PfkB, IPR029056:Ribokinase-like, IPR011877:Ribokinase" CG13369 11-Aug-17 DroID_v2017_08 Drer\rbks Scer\RBK1 Cele\F07A11.5 Xtro\rbks Mmus\Rbks Hsap\RBKS "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,supernumerary" FBgn0011745 Arp1 Actin-related protein 1 http://flybase.org/reports/FBgn0011745 FBgn0026240 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity anterograde axonal transport ; GO:0008089 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype retrograde axonal transport ; GO:0008090 | inferred from mutant phenotype axonal transport of mitochondrion ; GO:0019896 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from direct assay dynactin complex ; GO:0005869 | inferred from electronic annotation with InterPro:IPR029909 actin filament ; GO:0005884 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay "ARP1, Arp-1, grid, Arp1, CG6174, ARP87C, gdl, Arp, arp1, Actr87C, Arp87C, Arp87c" "IPR004001:Actin, conserved site, IPR029909:Actin-related protein 1 family, IPR004000:Actin family, IPR020902:Actin/actin-like conserved site" CG6174 11-Aug-17 DroID_v2017_08 "Drer\ankrd52b, Drer\actc1a, Drer\si:ch73-187m15.4, Drer\actr1, Drer\acta1a, Drer\zgc:86709, Drer\acta1b, Drer\acta2, Drer\si:ch211-241j12.3, Drer\actr10, Drer\zgc:86725, Drer\actb2, Drer\actb1, Drer\actc1b" "Scer\ARP1, Scer\ACT1, Scer\ARP9, Scer\ARP7" "Cele\arp-1, Cele\act-4" "Xtro\actb, Xtro\acta1, Xtro\act3, Xtro\actg1, Xtro\actc1, Xtro\actr1a, Xtro\acta2, Xtro\actr10, Xtro\ankrd52" "Mmus\Actg1, Mmus\Acta1, Mmus\Actc1, Mmus\Actl9, Mmus\Actb, Mmus\Acta2, Mmus\Actr1b, Mmus\Actr10, Mmus\Actl10, Mmus\Actl7a, Mmus\Actrt2, Mmus\Actl11, Mmus\Actr1a, Mmus\Actrt3, Mmus\Actbl2, Mmus\Actg2, Mmus\Actl7b, Mmus\Actrt1" "Hsap\ACTR1A, Hsap\ACTRT2, Hsap\POTEI, Hsap\ACTRT1, Hsap\POTEF, Hsap\POTEE, Hsap\ACTG1, Hsap\ACTR10, Hsap\ACTL7A, Hsap\ACTL7B, Hsap\ACTL9, Hsap\POTEJ, Hsap\ACTR1B, Hsap\ACTG2, Hsap\ACTL8, Hsap\ACTC1, Hsap\ACTA1, Hsap\ACTB, Hsap\ACTBL2, Hsap\ACTL10, Hsap\ACTA2, Hsap\ACTRT3" "increased cell death,mitotic cell cycle defective,locomotor behavior defective,cell lethalcell lethal,somatic clone" "synapse,embryonic/larval neuroblast,embryonic/larval brain,oocyte,germline clone" FBgn0031270 CG13689 - http://flybase.org/reports/FBgn0031270 protein_coding_gene - - - CG13689 - CG13689 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0250822 CG34222 - http://flybase.org/reports/FBgn0250822 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34222, NEST:bs08e11, NEST:bs11e07, NEST:bs12c06" - CG34222 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063495 GstE5 Glutathione S transferase E5 http://flybase.org/reports/FBgn0063495 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG17527, DmGSTE5, GstE5, GSTE5, gste5, gstE5" "IPR004045:Glutathione S-transferase, N-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold, IPR004046:Glutathione S-transferase, C-terminal" CG17527 11-Aug-17 DroID_v2017_08 "Drer\vars, Drer\eef1g, Drer\mars, Drer\eef1e1, Drer\gstt1a, Drer\gstr, Drer\gstt2, Drer\gstt1b" "Scer\URE2, Scer\YGR201C, Scer\GTT1, Scer\GTT2, Scer\TEF4, Scer\CAM1" "Cele\gst-29, Cele\gst-21" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Mars, Mmus\Gstt2, Mmus\Gstt3, Mmus\Gstt1, Mmus\Gstt4, Mmus\Eef1e1, Mmus\Vars, Mmus\Eef1g" "Hsap\GSTT1, Hsap\EEF1E1, Hsap\EEF1G, Hsap\GSTT2B, Hsap\MARS, Hsap\GSTT2, Hsap\VARS" viable FBgn0052509 CG32509 - http://flybase.org/reports/FBgn0052509 protein_coding_gene - - - "BcDNA:GH23462, CG32509" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082165 pkdt polka dots http://flybase.org/reports/FBgn0082165 gene - - - pkdt - - 11-Aug-17 DroID_v2017_08 - - - - - - "hemocyte,lamellocyte,supernumerary" FBgn0061158 l(1)7Fi lethal (1) 7Fi http://flybase.org/reports/FBgn0061158 gene - - - l(1)7Fi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041165 anon-F1 anon-F1 http://flybase.org/reports/FBgn0041165 gene - - - "F1, anon-F1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001300 ke kidney eye http://flybase.org/reports/FBgn0001300 - gene - - - ke - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,sterile" "eye,wing,antenna,macrochaeta,wing vein" FBgn0002111 l(2)a lethal (2) a http://flybase.org/reports/FBgn0002111 - gene - - - l(2)a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,body color defective" FBgn0263504 CR43493 - http://flybase.org/reports/FBgn0263504 non_protein_coding_gene - - - CR43493 - CR43493 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262594 CheA46a Chemosensory protein A 46a http://flybase.org/reports/FBgn0262594 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheA29a extracellular region ; GO:0005576 | inferred from sequence model "CheA46a, CG33800" - CG33800 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037125 CG14573 - http://flybase.org/reports/FBgn0037125 protein_coding_gene - - - CG14573 - CG14573 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002618 M(3)80 Minute (3) 80 http://flybase.org/reports/FBgn0002618 - gene - - - "QIII, M(3)LS4[Q-III], Q-III, M(3)LS4, M(3)Q-III, M(3)80" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,semidominant,heat sensitive,lethal,developmental rate defective,female sterile,recessive,male sterile,maternal effect,dominant" "eye,heat sensitive,macrochaeta,ocellus,antenna,arista,adult head,adult thorax,scutellum,adult mesothoracic segment,wing vein L2,wing vein L4,leg,prothoracic leg,tarsal segment,femur,sex comb,male genitalia,adult abdomen" FBgn0014368 nol no optic lobe http://flybase.org/reports/FBgn0014368 FBgn0052077 protein_coding_gene - - - "CG32077, nol" - CG32077 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263655 CG43646 - http://flybase.org/reports/FBgn0263655 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43646, mlncRNA42E5-2, lincRNA.258" - CG43646 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063646 CE2-3 "Calcineurin enhancer, chromosome 2, group 3" http://flybase.org/reports/FBgn0063646 gene - - - CE2-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265445 CR44345 - http://flybase.org/reports/FBgn0265445 non_protein_coding_gene - - - CR44345 - CR44345 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004552 Akh Adipokinetic hormone http://flybase.org/reports/FBgn0004552 "FBgn0004086, FBgn0004508" protein_coding_gene adipokinetic hormone receptor binding ; GO:0097005 | inferred from physical interaction with AkhR neuropeptide hormone activity ; GO:0005184 | traceable author statement neuropeptide hormone activity ; GO:0005184 | non-traceable author statement neuropeptide hormone activity ; GO:0005184 | inferred from direct assay lipid homeostasis ; GO:0055088 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype carbohydrate homeostasis ; GO:0033500 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern neuropeptide signaling pathway ; GO:0007218 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "akh, dAkh, AKH, Drm-AKH, Hrth, CG1171, Akh, AKH1" "IPR002047:Adipokinetic hormone, conserved site, IPR010475:Adipokinetic hormone/red pigment-concentrating hormone" CG1171 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult thorax

viable lipid particlefat FBgn0264679 CR43964 - http://flybase.org/reports/FBgn0264679 non_protein_coding_gene - - - CR43964 - CR43964 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020503 CLIP-190 Cytoplasmic linker protein 190 http://flybase.org/reports/FBgn0020503 - protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay microtubule plus-end binding ; GO:0051010 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSS1 myosin VI heavy chain binding ; GO:0070854 | inferred from physical interaction with jar protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q01989 actin binding ; GO:0003779 | inferred from direct assay microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity cellularization ; GO:0007349 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay spindle microtubule ; GO:0005876 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay microtubule plus-end ; GO:0035371 | inferred from direct assay axonal growth cone ; GO:0044295 | inferred from direct assay microtubule plus-end ; GO:0035371 | colocalizes_with inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay "CLIP190, Clip190, D-CLIP-19, Clip-190, D-CLIP-195, CG5020, D-CLIP-190, D-CLIP-90, CLIP-190, D-Clip-190, Clip- 190" "IPR000938:CAP Gly-rich domain, IPR032108:CLIP1, zinc knuckle" CG5020 11-Aug-17 DroID_v2017_08 "Drer\dmd, Drer\clip1b, Drer\clip1a, Drer\drp2, Drer\clip2, Drer\clip3" "Scer\BIK1, Scer\PAC2, Scer\NIP100" "Cele\dnc-1, Cele\clip-1" "Xtro\clip1, Xtro\clip3, Xtro\tpm1" "Mmus\Drp2, Mmus\Clip1, Mmus\Clip3, Mmus\Utrn, Mmus\Mmrn2, Mmus\Ccdc27, Mmus\Dctn1, Mmus\Clip2" "Hsap\NBPF8, Hsap\NBPF1, Hsap\NBPF3, Hsap\MMRN2, Hsap\CCDC27, Hsap\DCTN1, Hsap\NBPF15, Hsap\NBPF20, Hsap\NBPF11, Hsap\NBPF9, Hsap\CLIP1, Hsap\CLIP2, Hsap\DRP2, Hsap\NBPF14, Hsap\CLIP3, Hsap\NBPF6" viable FBgn0036062 CG6685 - http://flybase.org/reports/FBgn0036062 protein_coding_gene - - - CG6685 - CG6685 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019700 l(2)94 lethal (2) 94 http://flybase.org/reports/FBgn0019700 - gene - - - l(2)94 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000741 fs(1)A125 female sterile (1) A125 http://flybase.org/reports/FBgn0000741 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)125, fs(1)A125" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female semi-sterile,recessive,heat sensitive" dorsal appendage FBgn0036225 CG5883 - http://flybase.org/reports/FBgn0036225 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG5883 IPR002557:Chitin binding domain CG5883 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\C39D10.7, Cele\R02F2.4, Cele\cpg-2, Cele\cpg-1" - - Hsap\MATN2 viable FBgn0040846 CG17496 - http://flybase.org/reports/FBgn0040846 protein_coding_gene - - - CG17496 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266882 CR45343 - http://flybase.org/reports/FBgn0266882 non_protein_coding_gene - - - CR45343 - CR45343 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262545 CG43099 - http://flybase.org/reports/FBgn0262545 protein_coding_gene - - - CG43099 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030316 CG11695 - http://flybase.org/reports/FBgn0030316 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "c, CG11695" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG11695 11-Aug-17 DroID_v2017_08 "Drer\prdm5, Drer\zgc:113343, Drer\znf865, Drer\zgc:153116" - "Cele\hinf-1, Cele\ztf-23, Cele\lin-13" Xtro\prdm5 "Mmus\Zfp865, Mmus\Zfy2, Mmus\Zfy1, Mmus\Zfp667, Mmus\Zim1, Mmus\Zfp212" "Hsap\ZNF783, Hsap\ZNF763, Hsap\ZNF852, Hsap\ZNF30, Hsap\ZNF865, Hsap\ZNF544, Hsap\ZNF667, Hsap\ZNF805, Hsap\ZNF212, Hsap\PRDM5, Hsap\ZNF671, Hsap\ZNF100, Hsap\ZNF71, Hsap\ZNF227, Hsap\ZNF662" "viable,fertile" FBgn0262955 RpII140 RNA polymerase II 140kD subunit http://flybase.org/reports/FBgn0262955 protein_coding_gene "ribonucleoside binding ; GO:0032549 | inferred from electronic annotation with InterPro:IPR015712 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007120, InterPro:IPR007121, InterPro:IPR007641, InterPro:IPR007642, InterPro:IPR007644, InterPro:IPR007645, InterPro:IPR007646 RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000466005 DNA-directed RNA polymerase activity ; GO:0003899 | non-traceable author statement" transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9188 inferred from sequence or structural similarity with SGD:S000005677 "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9188 inferred from sequence or structural similarity with SGD:S000005677 DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | non-traceable author statement" "RNA Pol II 140, pol II, Pol IIc, Pol II, RNAP, wimp, PolII, rpII140/wimp, RNAP II, RNA Pol IIc, H5, polII, RNA Pol II, RP140, RNA pol II, CG3180, RNA polII, DmRP140, II, PolIIc, RNApolII, l(3)RplII140, RPII140, RpII140, RpII140[wimp], Rpll140, RPB2_DROME, Rpb2" "IPR015712:DNA-directed RNA polymerase, subunit 2, IPR007120:DNA-directed RNA polymerase, subunit 2, domain 6, IPR007121:RNA polymerase, beta subunit, conserved site, IPR007641:RNA polymerase Rpb2, domain 7, IPR007642:RNA polymerase Rpb2, domain 2, IPR007644:RNA polymerase, beta subunit, protrusion, IPR007645:RNA polymerase Rpb2, domain 3, IPR007646:RNA polymerase Rpb2, domain 4, IPR007647:RNA polymerase Rpb2, domain 5" CG3180 11-Aug-17 DroID_v2017_08 "Drer\polr2b, Drer\polr3b" "Scer\RET1, Scer\RPB2" "Cele\rpb-2, Cele\rpc-2" Xtro\polr2b "Mmus\Polr3b, Mmus\Polr2b" "Hsap\POLR3B, Hsap\POLR2B" DRSC16831 IEK 0.285200585 3.984708868 -0.012586792 -2.186545947 2.058492903 1.987690337 FBgn0264856 AP-2alpha::numb - http://flybase.org/reports/FBgn0264856 engineered_fusion_gene - - - "alpha-Adaptin::numb, AP-2alpha::numb" - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective secondary neuroblast FBgn0264429 CR43847 - http://flybase.org/reports/FBgn0264429 non_protein_coding_gene - - - "CR43847, lincRNA.851" - CR43847 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024635 l(2)k13825 lethal (2) k13825 http://flybase.org/reports/FBgn0024635 - gene - - - "138/25, l(2)k13825" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036395 CG17361 - http://flybase.org/reports/FBgn0036395 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG17361 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG17361 11-Aug-17 DroID_v2017_08 - - Cele\M03D4.4 - - - "viable,fertile" FBgn0035584 CG17030 - http://flybase.org/reports/FBgn0035584 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000002466 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with SGD:S000002466 cellular_component ; GO:0005575 | no biological data available CG17030 "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG17030 11-Aug-17 DroID_v2017_08 "Drer\ube2l3a, Drer\ube2l3b" Scer\UBC4 "Cele\ubc-18, Cele\ubc-24" Xtro\ube2l3 "Mmus\Ube2l3, Mmus\Ube2l6" "Hsap\UBE2L6, Hsap\UBE2L3" viable FBgn0027287 Gmap Golgi microtubule-associated protein http://flybase.org/reports/FBgn0027287 "FBgn0030649, FBgn0030650, FBgn0052587" protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2 protein targeting to Golgi ; GO:0000042 | inferred from electronic annotation with InterPro:IPR000237 Golgi organization ; GO:0007030 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from direct assay Golgi cis cisterna ; GO:0000137 | inferred from direct assay Golgi stack ; GO:0005795 | inferred from direct assay Golgi membrane ; GO:0000139 | inferred from direct assay cis-Golgi network ; GO:0005801 | "dGMAP, CG7821, CG6350, CG32587, CG33206, Gmap, l(1)G0168, GMAP210, GMAP, GMAP-210" IPR000237:GRIP domain CG33206 11-Aug-17 DroID_v2017_08 Drer\trip11 Scer\RUD3 Cele\sql-1 Xtro\trip11 Mmus\Trip11 Hsap\TRIP11 "visible,viable,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" "wing,costal cell,Golgi stackunspecified" FBgn0036592 CG13049 - http://flybase.org/reports/FBgn0036592 protein_coding_gene - Golgi organization ; GO:0007030 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay "BcDNA:RE26528, CG13049" - CG13049 11-Aug-17 DroID_v2017_08 - - Cele\T06E4.14 - - - "viable,visible" mesothoracic tergum FBgn0039228 CG6980 - http://flybase.org/reports/FBgn0039228 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.171, CG6980" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG6980 11-Aug-17 DroID_v2017_08 "Drer\stip1, Drer\si:dkey-33c12.4, Drer\ttc9c, Drer\ttc12, Drer\zgc:123010, Drer\sgut1, Drer\ttc9b, Drer\ttc9" "Scer\STI1, Scer\SGT2, Scer\CNS1" "Cele\ZK370.8, Cele\C17G10.2" "Xtro\stip1, Xtro\ttc9c, Xtro\sugt1" "Mmus\Ttc9, Mmus\Stip1, Mmus\Ttc9c, Mmus\Ttc12, Mmus\Ttc4, Mmus\Sugt1, Mmus\Ttc9b" "Hsap\SUGT1, Hsap\TTC9C, Hsap\TTC12, Hsap\TTC31, Hsap\TTC9, Hsap\STIP1, Hsap\TTC28, Hsap\TTC9B, Hsap\TTC4" viable FBgn0034245 UQCR-6.4 Ubiquinol-cytochrome c reductase 6.4 kDa subunit http://flybase.org/reports/FBgn0034245 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR015089 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from biological aspect of ancestor with PANTHER:PTN001035181 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:O14957 "mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:O14957" mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001035181 mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:O14957 "CG14482, UCRY, UQCR-6.4" IPR015089:Cytochrome b-c1 complex subunit 10 CG14482 11-Aug-17 DroID_v2017_08 - - Cele\ucr-11 - Mmus\Uqcr11 Hsap\UQCR11 viable FBgn0035622 TM9SF3 Transmembrane 9 superfamily protein member 3 http://flybase.org/reports/FBgn0035622 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000080197 "TM9SF3, CG10590" IPR004240:Nonaspanin (TM9SF) CG10590 11-Aug-17 DroID_v2017_08 "Drer\tm9sf1, Drer\tm9sf3" "Scer\TMN2, Scer\EMP70" Cele\Y41D4A.4 "Xtro\tm9sf3, Xtro\tm9sf1" "Mmus\Tm9sf3, Mmus\Tm9sf1" "Hsap\CHMP4A, Hsap\TM9SF1, Hsap\TM9SF3" viable FBgn0001936 l(2)25Fb lethal (2) 25Fb http://flybase.org/reports/FBgn0001936 - gene - - - "l(2)gdh-17, l(2)25Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035154 CG3344 - http://flybase.org/reports/FBgn0035154 protein_coding_gene serine-type carboxypeptidase activity ; GO:0004185 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 - CG3344 "IPR001563:Peptidase S10, serine carboxypeptidase, IPR029058:Alpha/Beta hydrolase fold" CG3344 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-122f10.4, Drer\scpep1, Drer\cpvl" "Scer\PRC1, Scer\YBR139W, Scer\KEX1" "Cele\F41C3.5, Cele\ctsa-1, Cele\ctsa-2, Cele\F13D12.6, Cele\Y32F6A.5, Cele\F22E12.1" "Xtro\cpvl, Xtro\scpep1, Xtro\ctsa" "Mmus\Ctsa, Mmus\Cpvl, Mmus\Scpep1" "Hsap\SCPEP1, Hsap\CTSA" viable DRSC08564 K 0.961224219 0.281742135 0.7139568 0.730464274 -1.600264103 -0.530084701 FBgn0283429 CR46272 - http://flybase.org/reports/FBgn0283429 pseudogene_attribute - - - CR46272 - CR46272 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005136 l(1)Y110 lethal (1) Y110 http://flybase.org/reports/FBgn0005136 - gene - - - l(1)Y110 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal ommatidium FBgn0036242 CG6793 - http://flybase.org/reports/FBgn0036242 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay CG6793 - CG6793 11-Aug-17 DroID_v2017_08 Drer\sclt1 - Cele\K09F6.9 "Xtro\cep152, Xtro\sclt1" Mmus\Hmmr Hsap\SYCP1 FBgn0039766 CG15536 - http://flybase.org/reports/FBgn0039766 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15536 - CG15536 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263449 CR43472 - http://flybase.org/reports/FBgn0263449 non_protein_coding_gene - - - CR43472 - CR43472 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035981 CG4452 - http://flybase.org/reports/FBgn0035981 protein_coding_gene - - - "cg4452, anon-WO0172774.118, CG4452" "IPR029660:FAM76A, IPR029661:FAM76B, IPR032017:FAM76 protein" CG4452 11-Aug-17 DroID_v2017_08 Drer\fam76b - Cele\K04F10.7 Xtro\fam76b "Mmus\Fam76b, Mmus\Fam76a" "Hsap\FAM76B, Hsap\FAM76A" "viable,fertile" DRSC10422 E 0.675023533 0.296345421 1.988799592 0.791214071 0.298275154 0.058985484 FBgn0002883 mus108 mutagen-sensitive 108 http://flybase.org/reports/FBgn0002883 - gene - - - mus108 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,radiation sensitive" FBgn0051183 CG31183 - http://flybase.org/reports/FBgn0051183 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 guanylate cyclase activity ; GO:0004383 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from sequence or structural similarity with Gyc76C receptor activity ; GO:0004872 | inferred from sequence or structural similarity with Gyc76C protein kinase activity ; GO:0004672 | NOT inferred from key residues guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 protein phosphorylation ; GO:0006468 | NOT inferred from key residues signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 cGMP-mediated signaling ; GO:0019934 | inferred from sequence or structural similarity with Gyc76C "integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Gyc76C plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "FBgn0038379, GYC, CG4224, CG11846, CG31183, DrGC-2, Gyc89A" "IPR000719:Protein kinase domain, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001170:Adenylyl cyclase class-4/guanylyl cyclase, IPR001828:Receptor, ligand binding region, IPR011009:Protein kinase-like domain, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase, IPR028082:Periplasmic binding protein-like I, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG31183 11-Aug-17 DroID_v2017_08 "Drer\npr1a, Drer\si:dkey-37g12.1, Drer\npr3, Drer\gucy2g, Drer\ints3, Drer\gucy2c, Drer\npr1b, Drer\npr2, Drer\si:ch73-139e5.4, Drer\gc3, Drer\gucy2f, Drer\gc2" - "Cele\gcy-21, Cele\gcy-17, Cele\Y92H12A.4, Cele\gcy-5, Cele\gcy-4, Cele\gcy-1, Cele\gcy-6, Cele\gcy-14, Cele\gcy-12, Cele\gcy-13, Cele\gcy-22, Cele\gcy-7, Cele\gcy-28, Cele\gcy-2, Cele\gcy-3, Cele\gcy-19" "Xtro\npr1, Xtro\gucy2c, Xtro\gucy2d, Xtro\gucy2f, Xtro\npr3" "Mmus\Npr2, Mmus\Npr3, Mmus\Gucy2g, Mmus\Ints3, Mmus\Gucy2e, Mmus\Gucy2f, Mmus\Gucy2c, Mmus\Gucy2d, Mmus\Npr1" "Hsap\GUCY2F, Hsap\INTS3, Hsap\GUCY2C, Hsap\NPR3, Hsap\NPR2, Hsap\GUCY2D, Hsap\NPR1" viable DRSC15554 K 0.80358871 0.401442482 0.142888164 0.679235797 0.915804915 4.396174871 FBgn0085795 CR41535 - http://flybase.org/reports/FBgn0085795 rRNA_gene - - - CR41535 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016853 l(1)N34 lethal (1) N34 http://flybase.org/reports/FBgn0016853 - gene - - - "l(1)N34, N34" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037974 CG12224 - http://flybase.org/reports/FBgn0037974 protein_coding_gene - - - CG12224 IPR023210:NADP-dependent oxidoreductase domain CG12224 11-Aug-17 DroID_v2017_08 Drer\srm "Scer\YPL088W, Scer\ARA2, Scer\AAD14" "Cele\F53F1.3, Cele\C07D8.6, Cele\F53F1.2, Cele\mec-14" Xtro\srm "Mmus\Kcnab2, Mmus\Srm" "Hsap\SRM, Hsap\KCNAB2" viable DRSC14480 K 0.289866199 0.397684889 0.680578299 0.387322333 1.860860217 0.235889008 FBgn0015965 l(2)46DEc lethal (2) 46DEc http://flybase.org/reports/FBgn0015965 - gene - - - "group 7, l(2)46DEc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027101 Dyrk3 Dual-specificity tyrosine phosphorylation-regulated kinase 3 http://flybase.org/reports/FBgn0027101 "FBgn0062988, FBgn0069975" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271" cellular_component ; GO:0005575 | no biological data available "CG40478, DDYRK3, BcDNA:RE60792, Dyrk3, DYRK3, Dm3, FBtr0100406, DmDyrk3" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG40478 11-Aug-17 DroID_v2017_08 "Drer\dyrk1aa, Drer\zgc:172180, Drer\dyrk1b, Drer\hipk3a, Drer\hipk3b, Drer\hipk1a, Drer\hipk2, Drer\dyrk2, Drer\dyrk4, Drer\dyrk1ab, Drer\si:ch211-160o17.4" Scer\YAK1 "Cele\hpk-1, Cele\mbk-1, Cele\mbk-2, Cele\C36B7.1" "Xtro\hipk1, Xtro\hipk3, Xtro\hipk2, Xtro\dyrk1a, Xtro\dyrk3, Xtro\dyrk2" "Mmus\Dyrk2, Mmus\Dyrk1b, Mmus\Dyrk1a, Mmus\Hipk1, Mmus\Hipk4, Mmus\Dyrk4, Mmus\Dyrk3, Mmus\Hipk3, Mmus\Hipk2" "Hsap\DYRK1B, Hsap\HIPK2, Hsap\HIPK1, Hsap\DYRK1A, Hsap\DYRK3, Hsap\HIPK3, Hsap\DYRK4, Hsap\HIPK4, Hsap\DYRK2" viable FBgn0031895 CG4497 - http://flybase.org/reports/FBgn0031895 protein_coding_gene - - - CG4497 IPR026716:FAM122 CG4497 11-Aug-17 DroID_v2017_08 Drer\fam122b - Cele\F46H5.2 Xtro\fam122a "Mmus\Fam122b, Mmus\Fam122a, Mmus\Fam122c" "Hsap\FAM122A, Hsap\FAM122C, Hsap\FAM122B" "viable,fertile" FBgn0062635 ER2-8A ER2-8A http://flybase.org/reports/FBgn0062635 gene - - - ER2-8A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032900 CG14401 - http://flybase.org/reports/FBgn0032900 protein_coding_gene - - - CG14401 - CG14401 11-Aug-17 DroID_v2017_08 - - "Cele\K11H12.7, Cele\K11H12.6, Cele\C15H9.9" - - - viable DRSC21710 I 3.551163599 1.243030575 -0.319566656 0.272119786 0.996092046 -0.172098153 FBgn0063368 Gpb5 Glycoprotein hormone beta 5 http://flybase.org/reports/FBgn0063368 protein_coding_gene hormone activity ; GO:0005179 | contributes_to inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Gpa2 G-protein coupled receptor binding ; GO:0001664 | contributes_to inferred from physical interaction with Lgr1 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from biological aspect of ancestor with PANTHER:PTN000162063 cell-cell signaling ; GO:0007267 | inferred from biological aspect of ancestor with PANTHER:PTN000162063 hormone-mediated signaling pathway ; GO:0009755 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000162063 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000162063 extracellular space ; GO:0005615 | inferred by curator from GO:0005179 "CG40041, Dmbeta, Gpb5, GPB5, beta-glycoprotein-hormone-related, gpb5" "IPR001545:Gonadotropin, beta subunit, IPR029034:Cystine-knot cytokine, IPR006208:Glycoprotein hormone subunit beta, cystine knot" CG40041 11-Aug-17 DroID_v2017_08 "Drer\lhb, Drer\tshba, Drer\gphb5, Drer\fshb" - Cele\T23B12.8 "Xtro\lhb, Xtro\fshb" "Mmus\Lhb, Mmus\Gphb5, Mmus\Fshb, Mmus\Tshb" "Hsap\LHB, Hsap\CGB3, Hsap\CGB7, Hsap\GPHB5, Hsap\CGB8, Hsap\FSHB, Hsap\TSHB, Hsap\CGB5, Hsap\CGB2, Hsap\CGB1" partially lethal - majority die FBgn0263344 CR43425 - http://flybase.org/reports/FBgn0263344 non_protein_coding_gene - - - CR43425 - CR43425 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032235 CG5096 - http://flybase.org/reports/FBgn0032235 protein_coding_gene - - - "CT16355, CG5096" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5" CG5096 11-Aug-17 DroID_v2017_08 Drer\zgc:153913 - Cele\lron-7 - - - viable DRSC02813 K 0.274781647 0.455684965 0.197854546 -0.212803788 2.158008308 -0.485972745 FBgn0052748 tRNA:Phe-GAA-1-1 transfer RNA:Phenylalanine-GAA 1-1 http://flybase.org/reports/FBgn0052748 tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "AE002566.trna4-PheGAA, tRNA:F:GAA:AE002566-a, CR32748, chrX.trna4-PheGAA, tRNA-Phe-GAA-1-1, tRNA:Phe-GAA-1-1, tRNA:CR32748, UUC" - CR32748 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014122 anon-96Ca anon-96Ca http://flybase.org/reports/FBgn0014122 - gene - - - anon-96Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033127 Tsp42Ef Tetraspanin 42Ef http://flybase.org/reports/FBgn0033127 protein_coding_gene molecular_function ; GO:0003674 | no biological data available determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG12845, Dm.Tsp42Ef, Tsp42Ef" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12845 11-Aug-17 DroID_v2017_08 "Drer\tspan17, Drer\tspan5a, Drer\cd63, Drer\tspan15, Drer\tspan5b, Drer\zgc:110329" - "Cele\tsp-7, Cele\tsp-12" - "Mmus\Cd63, Mmus\Tspan5, Mmus\Tspan17, Mmus\Tspan15" "Hsap\TSPAN5, Hsap\TSPAN17, Hsap\TSPAN15" "viable,long lived,RU486 conditional,female limited,short lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0002544 lem lemon http://flybase.org/reports/FBgn0002544 - gene - - - lem - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,semi-sterile,body color defective" FBgn0010877 l(3)05822 lethal (3) 05822 http://flybase.org/reports/FBgn0010877 FBgn0038599 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "l(3)05822, CG7129, l(3)5822, clot 3142, LD12970, 5822, L(3)05822" IPR001452:SH3 domain CG7129 11-Aug-17 DroID_v2017_08 "Drer\sh3d19, Drer\ncf4" - Cele\B0303.7 Xtro\sh3d19 "Mmus\Ncf4, Mmus\Sh3d19" Hsap\SH3D19 "lethal,recessive" FBgn0034856 yellow-d2 yellow-d2 http://flybase.org/reports/FBgn0034856 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CT27880, CG9891, yellow-d2, yel-d2, d2" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG9891 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC04591 IK 2.785719553 -0.005359327 0.412312804 -0.004518426 1.121096033 1.553029613 FBgn0028006 l(3)S115909 lethal (3) S115909 http://flybase.org/reports/FBgn0028006 gene - - - "1159/09, l(3)S115909" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003010 orn ornamented http://flybase.org/reports/FBgn0003010 - gene - - - orn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019676 mor(1)3 mortality gene (1)3 http://flybase.org/reports/FBgn0019676 - gene - - - mor(1)3 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0065990 doc docked http://flybase.org/reports/FBgn0065990 gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available doc - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,recessive,visible" wing FBgn0265486 BG00737 - http://flybase.org/reports/FBgn0265486 gene - - - BG00737 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085284 Blos3 "Biogenesis of lysosome-related organelles complex 1, subunit 3" http://flybase.org/reports/FBgn0085284 protein_coding_gene molecular_function ; GO:0003674 | no biological data available endosomal transport ; GO:0016197 | inferred from biological aspect of ancestor with PANTHER:PTN001592525 BLOC-1 complex ; GO:0031083 | inferred from biological aspect of ancestor with PANTHER:PTN001592525 BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:20914 "CG34255, Dm Blos3, BLOS3, NP_001097640, Blos3, blos3" "IPR017245:BLOC-1 complex, subunit 3" CG34255 11-Aug-17 DroID_v2017_08 Drer\bloc1s3 - - - Mmus\Bloc1s3 Hsap\BLOC1S3 FBgn0262286 mir-1001 mir-1001 stem loop http://flybase.org/reports/FBgn0262286 miRNA_gene - muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-1001, miR-1001, mir-1001, CR42993" - CR42993 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male limited" FBgn0038533 CG7523 - http://flybase.org/reports/FBgn0038533 protein_coding_gene - - - CG7523 IPR029399:TMEM192 family CG7523 11-Aug-17 DroID_v2017_08 Drer\tmem192 - - Xtro\tmem192 Mmus\Tmem192 Hsap\TMEM192 FBgn0036328 CG10749 - http://flybase.org/reports/FBgn0036328 protein_coding_gene L-malate dehydrogenase activity ; GO:0030060 | inferred from sequence or structural similarity with UniProtKB:P40926 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR015955 malate metabolic process ; GO:0006108 | inferred from electronic annotation with InterPro:IPR001252, InterPro:IPR010097 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P40926" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P40926 CG10749 "IPR001236:Lactate/malate dehydrogenase, N-terminal, IPR001252:Malate dehydrogenase, active site, IPR001557:L-lactate/malate dehydrogenase, IPR010097:Malate dehydrogenase, type 1, IPR015955:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR016040:NAD(P)-binding domain, IPR022383:Lactate/malate dehydrogenase, C-terminal" CG10749 11-Aug-17 DroID_v2017_08 Drer\mdh2 "Scer\MDH1, Scer\MDH3, Scer\MDH2" "Cele\mdh-1, Cele\mdh-2" Xtro\mdh2 Mmus\Mdh2 Hsap\MDH2 viable FBgn0037811 CG12592 - http://flybase.org/reports/FBgn0037811 protein_coding_gene - rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000529705 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000529705 "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000529705" "CG12592, CG12592-PA" - CG12592 11-Aug-17 DroID_v2017_08 "Drer\zgc:66447, Drer\slain2, Drer\mdn1, Drer\slain1a" Scer\MDN1 "Cele\D1086.9, Cele\Y6B3B.1, Cele\F55F10.1" "Xtro\slain1, Xtro\slain2" "Mmus\Slain1, Mmus\Samd15, Mmus\Tchhl1, Mmus\Slain2, Mmus\Mdn1" "Hsap\SLAIN1, Hsap\SLAIN2, Hsap\SAMD15, Hsap\MDN1" FBgn0038938 CG7084 - http://flybase.org/reports/FBgn0038938 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 neurogenesis ; GO:0022008 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG7084 "IPR020846:Major facilitator superfamily domain, IPR005828:Major facilitator, sugar transporter-like" CG7084 11-Aug-17 DroID_v2017_08 "Drer\slc22a7b.1, Drer\slc22a7b.3, Drer\LOC101884074, Drer\slc22a6l, Drer\slc22a5, Drer\slc22a13, Drer\zgc:175176, Drer\zmp:0000001102, Drer\LOC100334012, Drer\slc22a21, Drer\slc22a7b.2, Drer\sv2, Drer\oatx" "Scer\DTR1, Scer\QDR3, Scer\FLR1, Scer\TPO3, Scer\TPO2, Scer\GIT1, Scer\YHK8, Scer\QDR2, Scer\PHO84, Scer\AQR1, Scer\TPO1, Scer\QDR1" "Cele\Y66D12A.13, Cele\oct-1, Cele\Y57G11C.23, Cele\Y51A2D.18, Cele\C53B4.1, Cele\F32H5.4, Cele\ZK892.3, Cele\C46C2.2" Xtro\slc22a6 "Mmus\Slc22a14, Mmus\Slc22a5, Mmus\Svop, Mmus\Slc22a19, Mmus\Slc22a7, Mmus\Slc22a23, Mmus\Slc22a28, Mmus\Slc22a20, Mmus\Sv2c, Mmus\Slc22a26, Mmus\Slc22a21, Mmus\Slc22a27, Mmus\Slc22a22, Mmus\Slc22a2, Mmus\Slc22a29, Mmus\Slc22a4, Mmus\Slc22a6, Mmus\Slc22a16, Mmus\Slc22a8, Mmus\Slc22a30" "Hsap\SLC22A7, Hsap\SLC22A2, Hsap\SLC22A8, Hsap\SLC22A1, Hsap\SV2C, Hsap\SLC22A5, Hsap\SLC22A9, Hsap\SLC22A12, Hsap\SLC22A4, Hsap\SLC22A10, Hsap\SLC22A24, Hsap\SLC22A25, Hsap\SLC22A23, Hsap\SVOP, Hsap\SLC22A6, Hsap\SLC22A11, Hsap\SV2B" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,trichogen cell,mesothoracic tergum" FBgn0262249 mir-958 mir-958 stem loop http://flybase.org/reports/FBgn0262249 miRNA_gene - - - "mir-958, miR-958, CR42956, dme-miR-958" - CR42956 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during P-stage" "wing,wing vein,ectopic" FBgn0042131 CG18808 - http://flybase.org/reports/FBgn0042131 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003767 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003767 - CG18808 IPR003767:Malate/L-lactate dehydrogenase CG18808 11-Aug-17 DroID_v2017_08 - - "Cele\F36A2.3, Cele\VF13D12L.3" - - - viable FBgn0034228 CG14479 - http://flybase.org/reports/FBgn0034228 protein_coding_gene - - - CG14479 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032945 CG8665 - http://flybase.org/reports/FBgn0032945 protein_coding_gene "hydroxymethyl-, formyl- and related transferase activity ; GO:0016742 | inferred from electronic annotation with InterPro:IPR002376, InterPro:IPR005793 aldehyde dehydrogenase (NAD) activity ; GO:0004029 | inferred from biological aspect of ancestor with PANTHER:PTN000192421 formyltetrahydrofolate dehydrogenase activity ; GO:0016155 | inferred from biological aspect of ancestor with PANTHER:PTN000916306" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR011407, InterPro:IPR015590, InterPro:IPR016160, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163, InterPro:IPR029510 10-formyltetrahydrofolate catabolic process ; GO:0009258 | inferred from electronic annotation with InterPro:IPR011407 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR011407 biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR002376, InterPro:IPR005793" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011407 CG8665 "IPR001555:Phosphoribosylglycinamide formyltransferase, active site, IPR002376:Formyl transferase, N-terminal, IPR005793:Formyl transferase, C-terminal, IPR009081:Phosphopantetheine binding ACP domain, IPR011034:Formyl transferase, C-terminal-like, IPR011407:10-formyltetrahydrofolate dehydrogenase, IPR015590:Aldehyde dehydrogenase domain, IPR016160:Aldehyde dehydrogenase, cysteine active site, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR029510:Aldehyde dehydrogenase, glutamic acid active site" CG8665 11-Aug-17 DroID_v2017_08 "Drer\aldh9a1a.1, Drer\aldh1a3, Drer\aldh2.2, Drer\wu:fb14d09, Drer\aldh9a1b, Drer\aldh1l2, Drer\aldh8a1, Drer\aldh16a1, Drer\aldh2.1, Drer\aldh1l1, Drer\aldh1a2" "Scer\ALD6, Scer\ALD2, Scer\ALD5, Scer\ALD3, Scer\ALD4" "Cele\alh-2, Cele\alh-10, Cele\alh-3, Cele\alh-11" "Xtro\aldh9a1, Xtro\aldh1b1, Xtro\aldh2, Xtro\aldh1a3, Xtro\aldh1l1, Xtro\aldh1a1, Xtro\aldh1a2, Xtro\aldh16a1, Xtro\aldh1l2" "Mmus\Aldh1a7, Mmus\Aldh16a1, Mmus\Aldh8a1, Mmus\Aldh1a1, Mmus\Aldh1l2, Mmus\Aldh1a3, Mmus\Aldh2, Mmus\Aldh1a2, Mmus\Aldh9a1, Mmus\Aldh1b1, Mmus\Aldh1l1" "Hsap\ALDH2, Hsap\ALDH1L1, Hsap\ALDH1L2, Hsap\ALDH1A2, Hsap\ALDH1A1, Hsap\ALDH16A1, Hsap\ALDH1A3, Hsap\ALDH8A1, Hsap\ALDH9A1, Hsap\ALDH1B1" viable FBgn0038172 Adgf-D Adenosine deaminase-related growth factor D http://flybase.org/reports/FBgn0038172 protein_coding_gene adenosine deaminase activity ; GO:0004000 | inferred from direct assay growth factor activity ; GO:0008083 | inferred from direct assay adenosine catabolic process ; GO:0006154 | inferred from direct assay cell proliferation ; GO:0008283 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG9621, ADGF-D, adgfd, Adgf-D, ADGFD, AdgfD" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG9621 11-Aug-17 DroID_v2017_08 "Drer\ada, Drer\cecr1a, Drer\cecr1b, Drer\adal" Scer\AAH1 Cele\C44B7.12 "Xtro\cecr1, Xtro\adal, Xtro\ada.2, Xtro\ada" "Mmus\Adal, Mmus\Ada" "Hsap\ADAL, Hsap\ADA, Hsap\CECR1" viable FBgn0266428 CR43463 - http://flybase.org/reports/FBgn0266428 non_protein_coding_gene - - - "CR43463, anon-35Aa" - CR43463 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015506 l(3)EGX4 lethal (3) EGX4 http://flybase.org/reports/FBgn0015506 - gene - - - "PGX4, EGX4, l(3)EGX4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023044 l(1)5-39-1 lethal (1) 5-39-1 http://flybase.org/reports/FBgn0023044 - gene - - - l(1)5-39-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050279 CG30279 - http://flybase.org/reports/FBgn0050279 protein_coding_gene - - - CG30279 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265944 CR44731 - http://flybase.org/reports/FBgn0265944 non_protein_coding_gene - - - CR44731 - CR44731 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005076 fs(2)OW217 female sterile (2) OW217 http://flybase.org/reports/FBgn0005076 - gene - - - fs(2)OW217 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028632 ksh-15 ksh-15 http://flybase.org/reports/FBgn0028632 gene - - - ksh-15 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000960 fs(2)E7 female sterile (2) E7 http://flybase.org/reports/FBgn0000960 - gene - - - "fs2.7, fs(2)E7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "vitelline membrane,egg" FBgn0243515 nrv2::nrv3 - http://flybase.org/reports/FBgn0243515 engineered_fusion_gene - - - nrv2::nrv3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260393 CG17147 - http://flybase.org/reports/FBgn0260393 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG17147 IPR002557:Chitin binding domain CG17147 11-Aug-17 DroID_v2017_08 Drer\thbd - Cele\R02F2.4 - - Hsap\MATN2 viable FBgn0264479 CR43887 - http://flybase.org/reports/FBgn0264479 non_protein_coding_gene - - - CR43887 - CR43887 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263201 scaRNA:MeU1b-A234 small Cajal body-specific RNA : MeU1b-A234 http://flybase.org/reports/FBgn0263201 snoRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "scaDm46E3, snoRNA:46E1, Dm46E1, scaRNA:46E3, Dm46E3, scaRNA:MeU1b-A234" - CR43567 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033584 CG7737 - http://flybase.org/reports/FBgn0033584 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" - CG7737 "IPR002937:Amine oxidase, IPR023753:FAD/NAD(P)-binding domain" CG7737 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-275b16.2, Drer\smox, Drer\zgc:66484, Drer\paox1" Scer\FMS1 "Cele\amx-3, Cele\hpo-15, Cele\amx-1" "Xtro\LOC100145496, Xtro\paox, Xtro\smox" "Mmus\Kdm1b, Mmus\Paox, Mmus\Smox" "Hsap\SMOX, Hsap\PAOX, Hsap\KDM1B" viable FBgn0264999 CR44150 - http://flybase.org/reports/FBgn0264999 non_protein_coding_gene - - - "lincRNA.94, CR44150" - CR44150 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260481 CG32454 - http://flybase.org/reports/FBgn0260481 protein_coding_gene aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR007865 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR007865 - - "CG11367, CG32454" "IPR000994:Peptidase M24, IPR029149:Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR028980:Creatinase/Aminopeptidase P, N-terminal, IPR007865:Aminopeptidase P, N-terminal" CG32454 11-Aug-17 DroID_v2017_08 "Drer\xpnpep2, Drer\xpnpep3" "Scer\ICP55, Scer\FRA1" Cele\R119.2 Xtro\xpnpep3 "Mmus\Xpnpep3, Mmus\Xpnpep2" "Hsap\RBX1, Hsap\XPNPEP2, Hsap\XPNPEP3" viable FBgn0040874 CG15600 - http://flybase.org/reports/FBgn0040874 protein_coding_gene - - - CG15600 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000205 bos bordosteril http://flybase.org/reports/FBgn0000205 - gene - - - bos - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,fertile,male,female sterile,eye color defective" "eye,Malpighian tubule,pigment cell" FBgn0000064 Ald Aldolase http://flybase.org/reports/FBgn0000064 FBgn0064914 protein_coding_gene fructose-bisphosphate aldolase activity ; GO:0004332 | inferred from direct assay mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs glycolytic process ; GO:0006096 | inferred from direct assay mesoderm development ; GO:0007498 | non-traceable author statement M band ; GO:0031430 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay "CG6058, T12, T7, T6, T4, FBA, ald, ALD, BcDNA:LP07735, Ald, Aldolase, dALDOA" "IPR013785:Aldolase-type TIM barrel, IPR000741:Fructose-bisphosphate aldolase, class-I, IPR029768:Fructose-bisphosphate aldolase class-I active site" CG6058 11-Aug-17 DroID_v2017_08 "Drer\aldocb, Drer\aldoab, Drer\aldoaa, Drer\aldob, Drer\aldoca" - "Cele\aldo-1, Cele\aldo-2" "Xtro\aldoa, Xtro\aldoc, Xtro\aldob" "Mmus\Aldoa, Mmus\Aldob, Mmus\Aldoc, Mmus\Aldoart2, Mmus\Aldoart1" "Hsap\ALDOB, Hsap\ALDOA, Hsap\ALDOC" "paralytic,recessive,heat sensitive,short lived,neuroanatomy defective,progressive,viable,fertile,electrophoretic variant,fast,slow,visible,lethal" "adult brain,progressive,optic lobe,trichogen cell" FBgn0261293 CheB53b Chemosensory protein B 53b http://flybase.org/reports/FBgn0261293 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model "CheB53b, CG33457, CG33524" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG33524 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033482 CG1371 - http://flybase.org/reports/FBgn0033482 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR013784 - endomembrane system ; GO:0012505 | inferred from direct assay CG1371 "IPR013784:Carbohydrate-binding-like fold, IPR013783:Immunoglobulin-like fold" CG1371 11-Aug-17 DroID_v2017_08 Drer\nomo - Cele\nra-4 Xtro\nomo3 Mmus\Nomo1 "Hsap\NOMO3, Hsap\LOC102723728, Hsap\NOMO1" "partially lethal - majority die,some die during pupal stage" FBgn0011071 l(1)Q24 lethal (1) Q24 http://flybase.org/reports/FBgn0011071 FBgn0010210 gene - - - l(1)Q24 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028224 l(3)S005818 lethal (3) S005818 http://flybase.org/reports/FBgn0028224 gene - - - "58/18, 0058/18, l(3)S005818" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0267016 CR45460 - http://flybase.org/reports/FBgn0267016 non_protein_coding_gene - - - CR45460 - CR45460 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030668 CG8128 - http://flybase.org/reports/FBgn0030668 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797, InterPro:IPR020084" regulation of cell cycle ; GO:0051726 | inferred from direct assay - CG8128 "IPR000086:NUDIX hydrolase domain, IPR003293:Nudix hydrolase 6-like, IPR015797:NUDIX hydrolase domain-like, IPR020084:NUDIX hydrolase, conserved site, IPR020476:NUDIX hydrolase" CG8128 11-Aug-17 DroID_v2017_08 Drer\nudt6 - Cele\ndx-1 Xtro\nudt6 Mmus\Nudt6 "Hsap\NUDT18, Hsap\NUDT6" viable FBgn0003003 opb opaque broad http://flybase.org/reports/FBgn0003003 - gene - - - opb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,female sterile,male fertile,viable,male,poor,eye color defective" "wing,abdomen,genitalia,leg,adult abdomen,pigment cell" FBgn0033629 Tsp47F Tetraspanin 47F http://flybase.org/reports/FBgn0033629 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG9033, Dm.Tsp47F, Tsp47F" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG9033 11-Aug-17 DroID_v2017_08 "Drer\tspan7b, Drer\cd63, Drer\cd151, Drer\tspan11, Drer\cd151l, Drer\tspan7" - "Cele\tsp-14, Cele\tsp-3, Cele\tsp-7, Cele\tsp-2, Cele\tsp-1" "Xtro\cd151, Xtro\tspan6, Xtro\cd63" "Mmus\Cd63, Mmus\Cd151, Mmus\Tspan6, Mmus\Tspan7, Mmus\Tspan11" "Hsap\CD63, Hsap\TSPAN6, Hsap\TSPAN7, Hsap\TSPAN11, Hsap\CD151" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC07325 E -1.304622244 -1.174516611 -0.013770338 -1.697743159 0.01999032 -0.228397189 FBgn0034535 CG11110 - http://flybase.org/reports/FBgn0034535 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR000223 signal peptide processing ; GO:0006465 | inferred from biological aspect of ancestor with PANTHER:PTN000272698 protein processing involved in protein targeting to mitochondrion ; GO:0006627 | inferred from biological aspect of ancestor with PANTHER:PTN000272697 mitochondrial respiratory chain complex assembly ; GO:0033108 | inferred from biological aspect of ancestor with PANTHER:PTN000272697 mitochondrial inner membrane peptidase complex ; GO:0042720 | inferred from biological aspect of ancestor with PANTHER:PTN000272697 CG11110 "IPR000223:Peptidase S26A, signal peptidase I, IPR015927:Peptidase S24/S26A/S26B/S26C" CG11110 11-Aug-17 DroID_v2017_08 Drer\immp2l Scer\IMP2 Cele\immp-2 - Mmus\Immp2l Hsap\IMMP2L viable DRSC27355 EK 1.479846205 1.458789777 2.145063884 0.668947345 1.737248778 0.539701275 FBgn0250851 CG33981 - http://flybase.org/reports/FBgn0250851 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG33981, APC13, BEST:GH01256, Fab1" IPR008401:Apc13p CG33981 11-Aug-17 DroID_v2017_08 "Drer\anapc13, Drer\utp23" - Cele\C34E10.10 "Xtro\anapc13.1, Xtro\utp23" "Mmus\Anapc13, Mmus\Utp23" Hsap\ANAPC13 FBgn0031381 Npc2a Niemann-Pick type C-2a http://flybase.org/reports/FBgn0031381 protein_coding_gene lipopolysaccharide binding ; GO:0001530 | inferred from direct assay lipoteichoic acid binding ; GO:0070891 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from direct assay lipid antigen binding ; GO:0030882 | inferred from direct assay sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 intracellular cholesterol transport ; GO:0032367 | inferred from electronic annotation with InterPro:IPR033916 sterol homeostasis ; GO:0055092 | inferred from mutant phenotype sterol transport ; GO:0015918 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype ecdysteroid biosynthetic process ; GO:0045456 | inferred from genetic interaction with Npc2b synaptic target recognition ; GO:0008039 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "CT22505, DmML3, CG7291, dnpc2a, BEST:GH08376, BcDNA:RH53228, BcDNA:GH22047, npc2a, Npc2a, NPC2" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set, IPR033916:ML domain, Npc2 like" CG7291 11-Aug-17 DroID_v2017_08 "Drer\npc2, Drer\zgc:193725" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 "viable,fertile,short lived" Malpighian tubule DRSC00698 K 0.270171765 0.323355966 -0.381211452 0.264135258 2.008471713 1.145146139 FBgn0014178 ftz::Dr ftz::Dr http://flybase.org/reports/FBgn0014178 - engineered_fusion_gene - - - "ftz::msh, ftz::Dr" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266900 CR45360 - http://flybase.org/reports/FBgn0266900 non_protein_coding_gene - - - CR45360 - CR45360 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022332 fs(3)160 fs(3)160 http://flybase.org/reports/FBgn0022332 - gene - - - "fs160, fs(3)160" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030369 Cyp318a1 Cyp318a1 http://flybase.org/reports/FBgn0030369 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972" - "CG1786, 318a1, CG11364, Cyp318a1, Cyp318A1" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV, IPR017972:Cytochrome P450, conserved site" CG1786 11-Aug-17 DroID_v2017_08 "Drer\cyp4v7, Drer\cyp19a1b, Drer\cyp19a1a, Drer\cyp4f3, Drer\cyp46a1.3, Drer\cyp46a1.2, Drer\cyp46a1.4, Drer\zgc:123299, Drer\cyp20a1, Drer\cyp4t8, Drer\cyp4v8, Drer\cyp46a1.1, Drer\LOC100329425, Drer\cyp26a1, Drer\cyp26b1, Drer\cyp26c1" "Scer\ERG5, Scer\DIT2, Scer\ERG11" - "Xtro\cyp26b1, Xtro\mgc108213, Xtro\cyp26c1, Xtro\cyp19a1, Xtro\cyp20a1, Xtro\cyp4b1, Xtro\LOC100487918, Xtro\cyp4f22, Xtro\cyp26a1, Xtro\cyp4f2, Xtro\cyp4v2, Xtro\LOC100488227, Xtro\cyp4b1.2" "Mmus\Cyp4f39, Mmus\Cyp4f15, Mmus\Cyp4v3, Mmus\Cyp4f37, Mmus\Cyp4a32, Mmus\Cyp26a1, Mmus\Cyp4f14, Mmus\Cyp4f18, Mmus\Cyp26b1, Mmus\Cyp26c1, Mmus\Cyp4a10, Mmus\Cyp4f40, Mmus\Cyp20a1, Mmus\Cyp4a31, Mmus\Cyp4x1, Mmus\Cyp46a1, Mmus\Cyp4a12a, Mmus\Cyp4f16, Mmus\Cyp4b1, Mmus\Cyp4f13, Mmus\Cyp4a14, Mmus\Cyp19a1, Mmus\Cyp4a12b, Mmus\Cyp4f17" "Hsap\CYP26A1, Hsap\CYP4F12, Hsap\CYP4V2, Hsap\CYP4X1, Hsap\CYP4F22, Hsap\CYP4F11, Hsap\CYP19A1, Hsap\CYP4B1, Hsap\CYP4Z1, Hsap\CYP26B1, Hsap\CYP4A22, Hsap\CYP26C1, Hsap\CYP4F2, Hsap\CYP20A1, Hsap\CYP4A11, Hsap\CYP46A1, Hsap\CYP4F3" "viable,fertile" FBgn0021763 sim::trh sim::trh http://flybase.org/reports/FBgn0021763 - engineered_fusion_gene - - - sim::trh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036016 CG3306 - http://flybase.org/reports/FBgn0036016 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3306 IPR003409:MORN motif CG3306 11-Aug-17 DroID_v2017_08 "Drer\jph1b, Drer\jph2, Drer\morn4, Drer\als2a, Drer\jph1a, Drer\rsph1, Drer\morn5, Drer\als2b, Drer\rsph10b, Drer\jph3, Drer\si:ch211-146m13.3, Drer\morn2" - - "Xtro\rsph1, Xtro\jph2, Xtro\morn5, Xtro\jph1, Xtro\als2, Xtro\als2cl, Xtro\rsph10b" "Mmus\Jph4, Mmus\Morn5, Mmus\Jph3, Mmus\Jph2, Mmus\Morn2, Mmus\Morn3, Mmus\Als2cl, Mmus\Als2, Mmus\Morn1, Mmus\Rsph1, Mmus\Jph1, Mmus\Morn4" "Hsap\MORN5, Hsap\RSPH10B, Hsap\ALS2CL, Hsap\MORN4, Hsap\JPH1, Hsap\ALS2, Hsap\JPH2, Hsap\MORN1, Hsap\JPH3, Hsap\JPH4, Hsap\MORN2, Hsap\RSPH1, Hsap\MORN3, Hsap\RSPH10B2" viable FBgn0035667 Jon65Ai Jonah 65Ai http://flybase.org/reports/FBgn0035667 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG10475, CT29408, Jon65A, SP145, Jon65Ai, Jon65" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG10475 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Cela1, Mmus\C1s1, Mmus\C1s2" "Hsap\F9, Hsap\PROC" viable DRSC24837 K -0.684455362 0.449427691 -0.174294669 0.176657859 -0.836945439 1.540782932 FBgn0060450 l(3)S120307 lethal (3) S120307 http://flybase.org/reports/FBgn0060450 gene - - - "1203/07, l(3)S120307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0060807 l(3)S055009a lethal (3) S055009a http://flybase.org/reports/FBgn0060807 gene - - - "0550/09, l(3)S055009a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001381 l(1)2Bm lethal (1) 2Bm http://flybase.org/reports/FBgn0001381 - gene - - - "l(1)HC255, l(1)2Bm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0050446 Tdc2 Tyrosine decarboxylase 2 http://flybase.org/reports/FBgn0050446 protein_coding_gene "carboxy-lyase activity ; GO:0016831 | inferred from electronic annotation with InterPro:IPR002129, InterPro:IPR010977, InterPro:IPR021115 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 tyrosine decarboxylase activity ; GO:0004837 | inferred from sequence or structural similarity" cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010977 locomotory behavior ; GO:0007626 | inferred from mutant phenotype behavioral response to cocaine ; GO:0048148 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype oviposition ; GO:0018991 | inferred from mutant phenotype - "dTdc2, CG3686, CG30446, Tdc2, TDC2, tdc2, tdc" "IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR010977:Aromatic-L-amino-acid decarboxylase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase, IPR021115:Pyridoxal-phosphate binding site" CG30446 11-Aug-17 DroID_v2017_08 "Drer\ddc, Drer\hdc" - "Cele\basl-1, Cele\tdc-1, Cele\bas-1, Cele\hdl-1" "Xtro\hdc, Xtro\ddc" "Mmus\Ddc, Mmus\Hdc" "Hsap\DDC, Hsap\HDC" "locomotor rhythm defective,female sterile,recessive,locomotor behavior defective,semidominant,chemosensitive behavior defective,mating behavior defective,female limited,courtship behavior defective,starvation stress response defective" "adult brain,multidendritic neuron,type II bouton,embryonic/larval neuromuscular junction" FBgn0046162 Doe Downstream of Eyeless http://flybase.org/reports/FBgn0046162 gene - - - Doe - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016957 tilN touch insensitive larva N http://flybase.org/reports/FBgn0016957 - gene - - - "line 301, tilN" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0027131 l(3)B6 lethal (3) B6 http://flybase.org/reports/FBgn0027131 - gene - - - l(3)B6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051701 CG31701 - http://flybase.org/reports/FBgn0051701 protein_coding_gene - - - CG31701 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035199 tfc triforce http://flybase.org/reports/FBgn0035199 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype - "CG9134, tfc" "IPR001304:C-type lectin-like, IPR018378:C-type lectin, conserved site, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG9134 11-Aug-17 DroID_v2017_08 "Drer\hbl4, Drer\clec3a, Drer\LOC100331140, Drer\clec11a, Drer\illr4, Drer\acanb, Drer\si:dkey-216e24.3, Drer\hbl2, Drer\zmp:0000000924, Drer\illr3, Drer\si:ch73-86n18.1, Drer\zgc:174904, Drer\si:ch73-361h17.1, Drer\LOC101884413, Drer\si:ch211-232p21.6, Drer\colec11, Drer\si:dkey-187i8.2, Drer\si:ch211-193e13.5, Drer\LOC101884526, Drer\si:ch211-214k5.3, Drer\si:ch211-133n4.7, Drer\si:ch211-283g2.3, Drer\si:ch211-170d8.5, Drer\clec3ba, Drer\zmp:0000000937, Drer\si:ch73-111e15.1, Drer\LOC100007376, Drer\cd209, Drer\hbl3, Drer\clec3bb, Drer\si:dkey-61f9.1, Drer\illr1, Drer\illr2, Drer\hbl1, Drer\si:ch73-343l4.2, Drer\LOC101886537, Drer\si:ch73-343l4.8, Drer\si:dkey-61f9.2, Drer\LOC101882781, Drer\si:ch73-122g19.1" - "Cele\clec-4, Cele\clec-193, Cele\clec-9, Cele\clec-102, Cele\clec-26, Cele\clec-117, Cele\clec-160, Cele\clec-5, Cele\clec-184, Cele\clec-198, Cele\clec-6, Cele\clec-7, Cele\clec-38, Cele\C25G4.17, Cele\clec-28, Cele\clec-39, Cele\T15B7.1, Cele\clec-45, Cele\clec-83, Cele\clec-202, Cele\clec-185, Cele\clec-199, Cele\clec-149, Cele\clec-178, Cele\clec-31" "Xtro\colec11, Xtro\colec10, Xtro\reg4, Xtro\clec3a, Xtro\sftpa, Xtro\clec3b" "Mmus\Asgr1, Mmus\Clec4n, Mmus\Clec12b, Mmus\Cd209e, Mmus\Clec4e, Mmus\Cd209f, Mmus\Klrb1c, Mmus\Clec9a, Mmus\Asgr2, Mmus\Clec4f, Mmus\Clec4a1, Mmus\Fcer2a, Mmus\Bcan, Mmus\Acan, Mmus\Mgl2, Mmus\Clec4g, Mmus\Clec4b2, Mmus\Clec3a, Mmus\Cd209d, Mmus\Clec10a, Mmus\Clec4b1, Mmus\Olr1, Mmus\Klra1, Mmus\Mbl2, Mmus\Clec1a, Mmus\Klre1, Mmus\Cd209b, Mmus\Vcan, Mmus\Sell, Mmus\Colec12, Mmus\Cd209c, Mmus\Cd209a, Mmus\Clec11a, Mmus\Clec4a4, Mmus\Clec4d, Mmus\Sftpa1, Mmus\Cd207, Mmus\Clec3b, Mmus\Colec10, Mmus\Clec4a2, Mmus\Mbl1, Mmus\Sftpd, Mmus\Cd209g, Mmus\Colec11, Mmus\Clec4a3" "Hsap\CD209, Hsap\CLEC4G, Hsap\COLEC10, Hsap\CLEC4E, Hsap\CLEC4D, Hsap\CD207, Hsap\CLEC3A, Hsap\SFTPA1, Hsap\MBL2, Hsap\CLEC3B, Hsap\CLEC11A, Hsap\FCER2, Hsap\CLEC17A, Hsap\CLEC4F, Hsap\CLEC4M, Hsap\OLR1, Hsap\KLRG1, Hsap\COLEC11, Hsap\CLEC12B, Hsap\ASGR2, Hsap\ASGR1, Hsap\SFTPA2, Hsap\CLEC10A, Hsap\CLEC4C, Hsap\BCAN, Hsap\SFTPD, Hsap\ACAN, Hsap\CLEC4A, Hsap\CLEC7A, Hsap\CLEC6A, Hsap\SELL, Hsap\VCAN" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032224 Sps2 Selenophosphate synthetase 2 http://flybase.org/reports/FBgn0032224 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR004536 catalytic activity ; GO:0003824 | traceable author statement ATP binding ; GO:0005524 | traceable author statement purine nucleotide binding ; GO:0017076 | inferred from sequence or structural similarity selenide, water dikinase activity ; GO:0004756 | inferred from sequence or structural similarity with HGNC:19686" selenocysteine biosynthetic process ; GO:0016260 | inferred from sequence or structural similarity with HGNC:19686 - "SPS2, dsps2, Dsps2, CG5025, Sps2, dSPS2, sps2" "IPR004536:Selenophosphate synthetase, IPR010918:AIR synthase-related protein, C-terminal domain, IPR016188:PurM-like, N-terminal domain" CG5025 11-Aug-17 DroID_v2017_08 "Drer\sps2, Drer\sephs1" - Cele\seld-1 Xtro\sephs1 "Mmus\Sephs1, Mmus\Sephs2" "Hsap\SEPHS2, Hsap\SEPHS1" " embryonic stage | stage 13 , adult stage && oogenesis stage , larval stage , embryonic stage | gastrula , embryonic stage | stage <= 5 , adult stage , embryonic stage " " embryonic nervous system

, nurse cell

, oocyte

, midgut primordium

, organism

, embryonic digestive system

" viable FBgn0020872 anon-P97 anon-P97 http://flybase.org/reports/FBgn0020872 - gene - - - "2-P97, anon-P97" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0036377 CG10710 - http://flybase.org/reports/FBgn0036377 protein_coding_gene - - - CG10710 - CG10710 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045501 Gr22a Gustatory receptor 22a http://flybase.org/reports/FBgn0045501 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr2940.5, CG31662, Gr22a, GR22a" IPR013604:7TM chemoreceptor CG31662 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - DRSC22283 K -0.068837186 0.191432576 -0.327301367 0.007651483 0.154130124 1.602965159 FBgn0031231 mRpL10 mitochondrial ribosomal protein L10 http://flybase.org/reports/FBgn0031231 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q3MHY7 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AW249086 structural constituent of ribosome ; GO:0003735 | traceable author statement ribosome biogenesis ; GO:0042254 | inferred from electronic annotation with InterPro:IPR001790 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AW249086 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q3MHY7 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AW249086 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q3MHY7 inferred from sequence or structural similarity with UniProtKB:Q7Z7H8 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement intracellular ribonucleoprotein complex ; GO:0030529 | inferred from sequence or structural similarity with UniProtKB:Q3MHY7 "L10, CG11488, mRpL10" IPR001790:Ribosomal protein L10P CG11488 11-Aug-17 DroID_v2017_08 Drer\mrpl10 Scer\MRPL11 Cele\mrpl-10 Xtro\mrpl10 Mmus\Mrpl10 Hsap\MRPL10 "viable,visible" trichogen cell FBgn0052451 SPoCk Secretory Pathway Calcium atpase http://flybase.org/reports/FBgn0052451 protein_coding_gene "nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR008250, InterPro:IPR023299 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250 calcium-transporting ATPase activity ; GO:0005388 | inferred from sequence or structural similarity with SGD:S000003135 manganese-transporting ATPase activity ; GO:0015410 | inferred from sequence or structural similarity with SGD:S000003135" sequestering of calcium ion ; GO:0051208 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from mutant phenotype calcium-mediated signaling ; GO:0019722 | inferred from mutant phenotype fluid transport ; GO:0042044 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR006413 Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay peroxisome ; GO:0005777 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay" "CG7651, CG14449, CG32451, anon-WO0118547.249, SPoCk, SPoCK" "IPR018303:P-type ATPase, phosphorylation site, IPR001757:P-type ATPase, IPR004014:Cation-transporting P-type ATPase, N-terminal, IPR006068:Cation-transporting P-type ATPase, C-terminal, IPR006413:P-type ATPase, subfamily IIA, PMR1-type, IPR008250:P-type ATPase, A domain, IPR023214:HAD-like domain, IPR023298:P-type ATPase, transmembrane domain, IPR023299:P-type ATPase, cytoplasmic domain N" CG32451 11-Aug-17 DroID_v2017_08 "Drer\atp2a3, Drer\atp2a1, Drer\atp2a1l, Drer\si:dkey-28b4.8, Drer\atp2c1, Drer\atp2a2b, Drer\atp2a2a" "Scer\PMA1, Scer\ENA2, Scer\PMA2, Scer\ENA5, Scer\PMR1, Scer\ENA1" "Cele\sca-1, Cele\pmr-1" "Xtro\atp2a2, Xtro\atp2c2, Xtro\atp2c1, Xtro\atp2a1" "Mmus\Atp2a2, Mmus\Atp2c1, Mmus\Atp2a1, Mmus\Atp2a3, Mmus\Atp2c2" "Hsap\ATP2C1, Hsap\ATP2C2, Hsap\ATP2A2, Hsap\ATP2A1, Hsap\ATP2A3" viable Malpighian tubule DRSC11706 E 0.263156096 -1.397511711 3.436917197 -1.088587593 0.541954827 0.046866632 FBgn0037761 CG8534 - http://flybase.org/reports/FBgn0037761 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available CG8534 "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG8534 11-Aug-17 DroID_v2017_08 "Drer\elovl4a, Drer\elovl8b, Drer\elovl2, Drer\elovl8a, Drer\elovl1b, Drer\elovl7b, Drer\zgc:101858, Drer\dhrs7, Drer\elovl4b, Drer\elovl5, Drer\hsd17b8, Drer\elovl7a, Drer\elovl1a" "Scer\ELO2, Scer\ELO3, Scer\ELO1" "Cele\F25D1.5, Cele\elo-5, Cele\elo-4, Cele\dhs-25, Cele\dhs-14, Cele\dhs-11, Cele\ZK829.1, Cele\C06E4.3, Cele\Y47G6A.22, Cele\F26D2.15, Cele\F28H7.2, Cele\Y47G6A.21, Cele\elo-3" "Xtro\elovl5, Xtro\hsd17b8, Xtro\MGC79752, Xtro\dhrs7, Xtro\elovl2, Xtro\elovl7, Xtro\cbr4, Xtro\elovl1" "Mmus\Elovl5, Mmus\H2-Ke6, Mmus\Cbr4, Mmus\Elovl7, Mmus\Elovl2, Mmus\Elovl6, Mmus\Elovl1, Mmus\Elovl4, Mmus\Dhrs7" "Hsap\ELOVL6, Hsap\HSD17B8, Hsap\ELOVL7, Hsap\ELOVL4, Hsap\ELOVL5, Hsap\ELOVL1, Hsap\DHRS7, Hsap\CBR4, Hsap\ELOVL2" viable FBgn0001408 l(1)3Bc lethal (1) 3Bc http://flybase.org/reports/FBgn0001408 - gene - - - "zw-12, l(1)zw12, zw12, ZW-12, l(1)3Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone" "egg,germline clone,female reproductive system" FBgn0053881 His4:CG33881 His4:CG33881 http://flybase.org/reports/FBgn0053881 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33881, His4:CG33881" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33881 11-Aug-17 DroID_v2017_08 "Drer\zgc:153409, Drer\LOC100331412, Drer\si:ch73-368j24.14, Drer\LOC570405, Drer\si:ch211-113a14.6, Drer\hist1h4l, Drer\si:dkey-108k21.12, Drer\si:ch211-113a14.17, Drer\LOC562770, Drer\si:dkey-108k21.19, Drer\si:dkey-23a13.7, Drer\si:ch73-36p18.3, Drer\zgc:194989, Drer\si:dkey-108k21.28, Drer\LOC100150038, Drer\si:dkey-261m9.18, Drer\si:ch73-36p18.4, Drer\si:ch211-113a14.26, Drer\zgc:163040, Drer\LOC794549, Drer\LOC100329358, Drer\zgc:154164, Drer\si:dkey-261m9.17" "Scer\HHF1, Scer\HHF2" "Cele\his-14, Cele\his-38, Cele\his-50, Cele\his-10, Cele\his-64, Cele\his-56, Cele\his-37, Cele\his-46, Cele\his-1, Cele\his-67, Cele\his-26, Cele\his-60, Cele\his-28, Cele\his-18, Cele\his-31, Cele\his-5" "Xtro\LOC100493041, Xtro\hist1h4k, Xtro\hist1h4c" "Mmus\Hist1h4c, Mmus\Hist1h4a, Mmus\Hist2h4, Mmus\Hist1h4m, Mmus\Hist1h4d, Mmus\Hist1h4k, Mmus\Hist1h4i, Mmus\Hist1h4b, Mmus\Hist1h4n, Mmus\Hist1h4f, Mmus\Hist1h4j, Mmus\Hist1h4h, Mmus\Hist4h4" "Hsap\HIST1H4F, Hsap\HIST1H4A, Hsap\HIST2H4B, Hsap\HIST1H4K, Hsap\HIST1H4E, Hsap\HIST1H4H, Hsap\HIST1H4D, Hsap\HIST1H4J, Hsap\HIST1H4C, Hsap\HIST1H4L, Hsap\HIST1H4B, Hsap\HIST1H4I, Hsap\HIST2H4A, Hsap\HIST1H4G, Hsap\HIST4H4" FBgn0028291 l(1)G0400 lethal (1) G0400 http://flybase.org/reports/FBgn0028291 gene - - - l(1)G0400 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039864 CG11550 - http://flybase.org/reports/FBgn0039864 protein_coding_gene - - - CG11550 "IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG11550 11-Aug-17 DroID_v2017_08 "Drer\clvs2, Drer\rlbp1b, Drer\sec14l7, Drer\ttpa, Drer\sec14l8, Drer\ttpal, Drer\rlbp1a" "Scer\YKL091C, Scer\SFH5, Scer\SEC14" - "Xtro\clvs2, Xtro\sec14l5, Xtro\ttpal, Xtro\clvs1, Xtro\sec14l1, Xtro\sec14l3, Xtro\ttpa, Xtro\mospd2, Xtro\rlbp1" "Mmus\Ttpa, Mmus\Sec14l2, Mmus\Clvs1, Mmus\Sec14l1, Mmus\Rlbp1, Mmus\Sec14l3, Mmus\Ttpal, Mmus\Sec14l4, Mmus\Sec14l5, Mmus\Clvs2" "Hsap\SEC14L4, Hsap\TTPA, Hsap\SEC14L1, Hsap\SEC14L3, Hsap\CLVS2, Hsap\SEC14L6, Hsap\RLBP1, Hsap\SEC14L2, Hsap\TTPAL, Hsap\SEC14L5, Hsap\CLVS1" FBgn0004665 ms(3)HO5B male sterile (3) HO5B http://flybase.org/reports/FBgn0004665 "FBgn0002835, FBgn0002837, FBgn0005314" gene - - - "ms(3)m2, ms(3)ms2[5A], ms(3)ms2, ms(3)HO5B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" "testis,spermatozoon" FBgn0263831 Gen XPG-like endonuclease http://flybase.org/reports/FBgn0263831 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR008918, InterPro:IPR020045 endodeoxyribonuclease activity ; GO:0004520 | inferred from direct assay endonuclease activity ; GO:0004519 | inferred from sequence or structural similarity double-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008311 | inferred from direct assay single-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008310 | inferred from direct assay 5'-3' exodeoxyribonuclease activity ; GO:0035312 | inferred from direct assay" "DNA repair ; GO:0006281 | inferred from mutant phenotype inferred from genetic interaction with Blm DNA catabolic process, exonucleolytic ; GO:0000738 | inferred from direct assay double-strand break repair ; GO:0006302 | inferred from mutant phenotype DNA catabolic process, endonucleolytic ; GO:0000737 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "Gen, mus324, DmGEN, CG10670, BcDNA:GM10765" "IPR006084:XPG/Rad2 endonuclease, IPR006085:XPG N-terminal, IPR006086:XPG-I domain, IPR008918:Helix-hairpin-helix motif, class 2, IPR020045:5'-3' exonuclease, C-terminal domain, IPR029060:PIN domain-like" CG10670 11-Aug-17 DroID_v2017_08 "Drer\zgc:110269, Drer\fen1" "Scer\YEN1, Scer\RAD27" "Cele\xpg-1, Cele\crn-1" "Xtro\gen1, Xtro\fen1" "Mmus\Gen1, Mmus\Fen1" "Hsap\FEN1, Hsap\GEN1" FBgn0083975 Nlg4 Neuroligin 4 http://flybase.org/reports/FBgn0083975 protein_coding_gene receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 neurexin family protein binding ; GO:0042043 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 "sleep ; GO:0030431 | inferred from mutant phenotype modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synaptic transmission, GABAergic ; GO:0051932 | inferred from direct assay synapse assembly ; GO:0007416 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538" cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 "CG31209, CG5035, BcDNA:AT13703, CG5030, CG31499, CG15683, CG15682, CG34139, Nlg4, dnlg4" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029058:Alpha/Beta hydrolase fold" CG34139 11-Aug-17 DroID_v2017_08 "Drer\nlgn4b, Drer\nlgn2a, Drer\si:ch211-93f2.1, Drer\ces2, Drer\nlgn1, Drer\ces3, Drer\nlgn4a, Drer\nlgn3a, Drer\nlgn3b, Drer\cel.1, Drer\cell, Drer\nlgn2b" - "Cele\nlg-1, Cele\W02B12.4, Cele\ZC376.1, Cele\T02B5.1, Cele\T02B5.3, Cele\ZK994.1, Cele\Y75B8A.3, Cele\glit-1, Cele\ZC376.3, Cele\ZC376.2" "Xtro\ces3, Xtro\ces2, Xtro\cel, Xtro\LOC100494782, Xtro\nlgn3, Xtro\nlgn4x, Xtro\nlgn2" "Mmus\Ces3a, Mmus\Nlgn3, Mmus\Ces2b, Mmus\Ces2e, Mmus\Cel, Mmus\Ces1g, Mmus\Ces5a, Mmus\Ces1e, Mmus\Ces1c, Mmus\Ces2g, Mmus\Ces2c, Mmus\Ces2f, Mmus\Nlgn1, Mmus\Ces1h, Mmus\Ces4a, Mmus\Ces3b, Mmus\Ces1d, Mmus\Nlgn2, Mmus\Ces1b, Mmus\Ces1f, Mmus\Ces2a, Mmus\Ces2h" "Hsap\CES5A, Hsap\NLGN4X, Hsap\NLGN2, Hsap\CES4A, Hsap\NLGN4Y, Hsap\CES2, Hsap\NLGN3, Hsap\NLGN1, Hsap\CES1, Hsap\CEL, Hsap\CES3" "lethal,sleep defective,heat sensitive,neuroanatomy defective,neurophysiology defective,viable,visible" "l-LNv neuron,trichogen cell" DRSC22243 IE 1.558935339 -2.039759475 1.667793225 -1.05426555 0.126635893 0.599242554 FBgn0026737 CG6171 - http://flybase.org/reports/FBgn0026737 - protein_coding_gene endodeoxyribonuclease activity ; GO:0004520 | inferred from direct assay 3'-5' exonuclease activity ; GO:0008408 | inferred from direct assay DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906 | inferred from direct assay "double-strand break repair ; GO:0006302 | inferred from sequence or structural similarity with HGNC:28724 DNA catabolic process, endonucleolytic ; GO:0000737 | inferred from direct assay single strand break repair ; GO:0000012 | inferred from sequence or structural similarity with HGNC:28724 nucleic acid phosphodiester bond hydrolysis ; GO:0090305 | inferred from direct assay" nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:28724 "anon-Becker2, CG6171" "IPR019406:Zinc finger, C2H2, APLF-like" CG6171 11-Aug-17 DroID_v2017_08 "Drer\zgc:165656, Drer\si:ch1073-147h9.1" - - Xtro\aplf Mmus\Aplf Hsap\APLF viable FBgn0085542 CG40949 - http://flybase.org/reports/FBgn0085542 protein_coding_gene - - - CG40949 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001673 l(1)EN10a lethal (1) from Eugene Nonautonomous 10a http://flybase.org/reports/FBgn0001673 - gene - - - l(1)EN10a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0264381 CR43833 - http://flybase.org/reports/FBgn0264381 non_protein_coding_gene - - - CR43833 - CR43833 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005215 l(3)ET6 lethal Elaine Tasaka 6 http://flybase.org/reports/FBgn0005215 - gene - - - l(3)ET6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" FBgn0033110 CG9447 - http://flybase.org/reports/FBgn0033110 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG9447 IPR002656:Acyltransferase 3 CG9447 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-9, Cele\oac-32, Cele\ndg-4, Cele\oac-54, Cele\oac-3, Cele\oac-5, Cele\oac-39, Cele\oac-31, Cele\oac-55, Cele\oac-7, Cele\oac-53, Cele\oac-50, Cele\nrf-6, Cele\rhy-1, Cele\oac-6, Cele\oac-20, Cele\oac-46, Cele\oac-14" - Mmus\Oacyl - viable FBgn0066343 lis lis http://flybase.org/reports/FBgn0066343 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available lis - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0015888 anon-6Eb anon-6Eb http://flybase.org/reports/FBgn0015888 - gene - - - anon-6Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022176 l(2)k05416 lethal (2) k05416 http://flybase.org/reports/FBgn0022176 - gene - - - l(2)k05416 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003157 pte pterygion http://flybase.org/reports/FBgn0003157 - gene - - - pte - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced,visible,recessive" "wing,eye,adult abdomen" FBgn0012024 tRNA:Tyr-GTA-1-8 transfer RNA:Tyrosine-GTA 1-8 http://flybase.org/reports/FBgn0012024 "FBgn0003849, FBgn0012014, FBgn0051435, FBgn0060005" tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "Tyr-tRNA T85a, tRNA-Tyr, 85Aa, tRNA[Tyr][[1gamma]], AE002708.trna57-TyrGTA, tRNA:Y, tRNA:Y:GTA:AE002708-a, CR31435, tRNA:tyr1:85Aa, tRNA[Tyr], chr3R.trna63-TyrGTA, tRNA:Tyr-GTA-1-8, tRNA:Y1:85Aa, tRNA-Tyr-GTA-1-8, UAC" - CR31435 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084972 l(3)S016805 l(3)S016805 http://flybase.org/reports/FBgn0084972 gene - - - l(3)S016805 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036527 CG7304 - http://flybase.org/reports/FBgn0036527 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern oligosaccharide biosynthetic process ; GO:0009312 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 - "CG7304, dppGalNAcT11" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG7304 11-Aug-17 DroID_v2017_08 "Drer\LOC101882942, Drer\galnt18b, Drer\galnt8b, Drer\galnt10, Drer\galnt7, Drer\galnt13, Drer\galnt18a, Drer\LOC568645, Drer\wbscr17, Drer\poc1bl, Drer\galnt3, Drer\LOC103910015, Drer\galnt1, Drer\galnt11, Drer\galnt12, Drer\galnt6, Drer\LOC101886587, Drer\galnt8a.1, Drer\LOC100535692, Drer\si:ch211-15e22.3, Drer\galnt9, Drer\LOC100334784" - "Cele\gly-8, Cele\gly-10" "Xtro\galnt1, Xtro\galnt7, Xtro\galnt10, Xtro\galnt9, Xtro\galnt15, Xtro\wbscr17, Xtro\galnt6.1, Xtro\galnt13, Xtro\galnt4, Xtro\galnt12" "Mmus\Galnt13, Mmus\Galnt7, Mmus\Galntl6, Mmus\Galnt10, Mmus\Galntl5, Mmus\Galnt3, Mmus\Galnt5, Mmus\Galnt4, Mmus\Galnt12, Mmus\Galnt11, Mmus\Galnt9, Mmus\Wbscr17, Mmus\Galnt6, Mmus\Galnt1, Mmus\Galnt15, Mmus\Galnt18" "Hsap\GALNTL6, Hsap\GALNT1, Hsap\GALNTL5, Hsap\GALNT12, Hsap\GALNT18, Hsap\GALNT15, Hsap\POC1B-GALNT4, Hsap\GALNT4, Hsap\GALNT3, Hsap\GALNT8, Hsap\GALNT6, Hsap\GALNT13, Hsap\WBSCR17, Hsap\GALNT9, Hsap\GALNT5, Hsap\GALNT10, Hsap\GALNT7, Hsap\GALNT11" "viable,fertile" FBgn0029657 CG12535 - http://flybase.org/reports/FBgn0029657 protein_coding_gene - - - CG12535 - CG12535 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035249 CG17249 - http://flybase.org/reports/FBgn0035249 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic cell cycle checkpoint ; GO:0007093 | inferred from sequence or structural similarity with HGNC:9343 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:9343 CG17249 IPR018800:Proline-rich protein PRCC CG17249 11-Aug-17 DroID_v2017_08 Drer\prcc - Cele\C39E9.11 Xtro\prcc Mmus\Prcc Hsap\PRCC viable FBgn0011218 emm emmenthal http://flybase.org/reports/FBgn0011218 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(2)06268, emm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" Nebenkern FBgn0024984 CG3457 - http://flybase.org/reports/FBgn0024984 - protein_coding_gene - - - "EG:17E2.1, CG3457" - CG3457 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0020525 mit(3)r135 mitotic r135 http://flybase.org/reports/FBgn0020525 - gene - - - mit(3)r135 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014180 grb gorbun http://flybase.org/reports/FBgn0014180 - gene - - - "gor, grb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267275 CR45711 - http://flybase.org/reports/FBgn0267275 non_protein_coding_gene - - - "lincRNA.1017, CR45711" - CR45711 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035089 Phk-3 Pherokine 3 http://flybase.org/reports/FBgn0035089 protein_coding_gene - response to bacterium ; GO:0009617 | inferred from expression pattern metamorphosis ; GO:0007552 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | inferred from sequence model "CG9358, BcDNA:RE09339, Phk-3, PHK-3, DmelCSP3" IPR005055:Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 CG9358 11-Aug-17 DroID_v2017_08 Drer\ifit15 - - - - - "viable,visible" mesothoracic tergum FBgn0027958 l(3)S147913 lethal (3) S147913 http://flybase.org/reports/FBgn0027958 gene - - - "1479/13, l(3)S147913" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0051406 CG31406 - http://flybase.org/reports/FBgn0051406 protein_coding_gene molecular_function ; GO:0003674 | no biological data available notum morphogenesis ; GO:0048802 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "BcDNA:AT13367, CG31406" - CG31406 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal - all die before end of P-stage,some die during pharate adult stage" "trichogen cell,scutellum" FBgn0021881 l(2)k13506 lethal (2) k13506 http://flybase.org/reports/FBgn0021881 - gene - - - l(2)k13506 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002430 l(3)F60 lethal (3) F60 http://flybase.org/reports/FBgn0002430 - gene - - - "l(3)60, l(3)F60" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,scutum" FBgn0011473 l(3)neo40 lethal (3) neo40 http://flybase.org/reports/FBgn0011473 - gene - - - l(3)neo40 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067672 omelet omelet http://flybase.org/reports/FBgn0067672 gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - omelet - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0070047 3L-215-13 3L-215-13 http://flybase.org/reports/FBgn0070047 gene molecular_function ; GO:0003674 | no biological data available eggshell formation ; GO:0030703 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3L-215-13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg,germline clone,non-rescuable maternal effect,dorsal appendage,maternal effect" FBgn0031645 CG3036 - http://flybase.org/reports/FBgn0031645 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from direct assay "151989_at, CT10168, CG3036" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG3036 11-Aug-17 DroID_v2017_08 "Drer\slc17a7a, Drer\slc17a8, Drer\slc17a6b, Drer\si:ch1073-513e17.1, Drer\ppt1, Drer\slc17a5, Drer\slc17a6a, Drer\slc17a9a" "Scer\DAL5, Scer\YIL166C, Scer\TNA1, Scer\THI73" "Cele\F47B8.10, Cele\Y19D10A.5, Cele\C18H9.5, Cele\Y51B9A.6, Cele\vglu-2, Cele\C01B4.7, Cele\vglu-3, Cele\R10D12.1, Cele\slc-17.4, Cele\slc-17.7, Cele\slc-17.8, Cele\slc-17.9, Cele\H11E01.2, Cele\T22F3.11, Cele\slc-17.2, Cele\T01H3.3, Cele\D1046.4, Cele\F44E7.7, Cele\slc-17.3, Cele\C18D1.2, Cele\K08C7.1, Cele\T28H11.8, Cele\T19D12.9, Cele\T02B11.6, Cele\M162.5, Cele\slc-17.6, Cele\T27D12.1, Cele\Y19D10A.8, Cele\W04C9.6, Cele\T22F3.8, Cele\Y4C6B.4, Cele\C35A5.3, Cele\F56A4.10, Cele\T22F3.10, Cele\F56A4.12, Cele\slc-17.1, Cele\cima-1, Cele\K11G9.5, Cele\Y15E3A.4, Cele\Y19D10A.11, Cele\F11A5.9, Cele\Y4C6B.3, Cele\T22F3.7, Cele\Y19D10A.4, Cele\eat-4, Cele\F59A1.13, Cele\M117.1, Cele\C39E9.7, Cele\slc-17.5, Cele\F10C2.7, Cele\C01B4.8, Cele\F41C3.2, Cele\T19D12.10" Xtro\slc17a7 "Mmus\Slc17a4, Mmus\Slc17a3, Mmus\Slc17a6, Mmus\Slc17a5, Mmus\Slc17a8, Mmus\Slc17a7, Mmus\Slc17a2, Mmus\Slc37a4, Mmus\Slc17a1" "Hsap\SLC17A5, Hsap\SLC17A8, Hsap\SLC17A7, Hsap\SLC17A4, Hsap\SLC37A4, Hsap\SLC17A2, Hsap\SLC17A6, Hsap\SLC17A3, Hsap\SLC17A1" viable rhabdomere R7 FBgn0036262 CG6910 - http://flybase.org/reports/FBgn0036262 protein_coding_gene inositol oxygenase activity ; GO:0050113 | inferred from electronic annotation with InterPro:IPR007828 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR007828 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR007828 inositol catabolic process ; GO:0019310 | inferred from electronic annotation with InterPro:IPR007828 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR007828 CG6910 IPR007828:Inositol oxygenase CG6910 11-Aug-17 DroID_v2017_08 Drer\miox - Cele\C54E4.5 Xtro\miox Mmus\Miox Hsap\MIOX "viable,fertile" FBgn0027115 mei-P37 mei-P37 http://flybase.org/reports/FBgn0027115 - gene - - - mei-P37 - - 11-Aug-17 DroID_v2017_08 - - - - - - meiotic cell cycle defective FBgn0010301 fs(2)lto3 female sterile (2) lto3 http://flybase.org/reports/FBgn0010301 "FBgn0000990, FBgn0000991, FBgn0004802" gene molecular_function ; GO:0003674 | no biological data available dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "fs(2)ltoRE57, fs(2)lo-C, fs(2)lto3" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0040751 CG13018 - http://flybase.org/reports/FBgn0040751 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from biological aspect of ancestor with PANTHER:PTN002007797 mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from sequence or structural similarity with SGD:S000003795 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN002007797 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000003795 CG13018 IPR018793:Cytochrome c oxidase assembly protein PET191 CG13018 11-Aug-17 DroID_v2017_08 Drer\coa5 Scer\PET191 Cele\Y18D10A.16 Xtro\coa5 Mmus\Coa5 Hsap\COA5 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0070021 BG00977 BG00977 http://flybase.org/reports/FBgn0070021 gene - - - BG00977 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0031856 CG11322 - http://flybase.org/reports/FBgn0031856 protein_coding_gene molecular_function ; GO:0003674 | no biological data available DNA demethylation ; GO:0080111 | inferred from biological aspect of ancestor with PANTHER:PTN000559411 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000559411 CG11322 IPR006640:SprT-like CG11322 11-Aug-17 DroID_v2017_08 Drer\acrc Scer\FYV8 Cele\ZK328.4 - - Hsap\GCNA viable FBgn0017485 Su(var)315 Suppressor of variegation 315 http://flybase.org/reports/FBgn0017485 - gene - - - Su(var)315 - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,viable" FBgn0033608 CG13220 - http://flybase.org/reports/FBgn0033608 protein_coding_gene - - - CG13220 - CG13220 11-Aug-17 DroID_v2017_08 - - Cele\C09G9.1 - - - FBgn0053498 CR33498 - http://flybase.org/reports/FBgn0053498 pseudogene_attribute - - - "CG33498, CR33498" - CR33498 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082596 drmo-o57 drymouth o57 http://flybase.org/reports/FBgn0082596 gene - - - drmo-o57 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024855 l(3)96Bg lethal (3) 96Bg http://flybase.org/reports/FBgn0024855 - gene - - - l(3)96Bg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028216 l(3)S008418 lethal (3) S008418 http://flybase.org/reports/FBgn0028216 gene - - - "1483/18, 1398/10, 1193/13, 0256/37, 0092/23, 0084/18, l(3)S008418" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043871 nompF no mechanoreceptor potential F http://flybase.org/reports/FBgn0043871 gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - nompF - - 11-Aug-17 DroID_v2017_08 - - - - - - "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective" "wing,leg,macrochaeta,adult antennal nerve" FBgn0034206 CG18469 - http://flybase.org/reports/FBgn0034206 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT30190, CG18469" - CG18469 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015958 l(1)m-C lethal (1) m-Caggese http://flybase.org/reports/FBgn0015958 - gene - - - l(1)m-C - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051015 PH4alphaPV prolyl-4-hydroxylase-alpha PV http://flybase.org/reports/FBgn0051015 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG9713, CG31015, PH4alphaPV" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG31015 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\p4ha3, Drer\p4ha1a, Drer\p4ha2, Drer\zgc:152670, Drer\zgc:158254, Drer\p4htm" - "Cele\Y43F8B.19, Cele\phy-3, Cele\phy-4, Cele\C14E2.4, Cele\phy-2, Cele\dpy-18" "Xtro\p4ha1, Xtro\p4ha3, Xtro\p4ha2" "Mmus\P4ha3, Mmus\P4ha1, Mmus\P4htm, Mmus\P4ha2" "Hsap\P4HA3, Hsap\P4HTM, Hsap\P4HA2, Hsap\P4HA1" viable FBgn0054026 CG34026 - http://flybase.org/reports/FBgn0054026 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1064, CG34026" IPR031734:Transcription activator MBF2 CG34026 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265593 CR44420 - http://flybase.org/reports/FBgn0265593 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR44420 - CR44420 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263089 CR43357 - http://flybase.org/reports/FBgn0263089 non_protein_coding_gene - - - CR43357 - CR43357 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267082 CR45526 - http://flybase.org/reports/FBgn0267082 non_protein_coding_gene - - - CR45526 - CR45526 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067084 M8 M8 http://flybase.org/reports/FBgn0067084 gene - - - "M8, m8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective,lethal,viable" "eye,pigment cell" FBgn0037453 CG10690 - http://flybase.org/reports/FBgn0037453 protein_coding_gene - - - CG10690 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033241 CG2915 - http://flybase.org/reports/FBgn0033241 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" endomembrane system ; GO:0012505 | inferred from direct assay extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 vesicle ; GO:0031982 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay CG2915 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG2915 11-Aug-17 DroID_v2017_08 "Drer\cpa5, Drer\cpa2, Drer\cpb2, Drer\cpa4, Drer\cpa6, Drer\cpb1, Drer\cpa1, Drer\cpo" Scer\ECM14 "Cele\suro-1, Cele\W01A8.6, Cele\Y47G6A.19, Cele\T06A4.3, Cele\ZC434.9, Cele\Y18H1A.9, Cele\F02D8.4, Cele\T06A4.1, Cele\Y59C2A.1" "Xtro\cpo, Xtro\LOC100487462, Xtro\cpa1, Xtro\LOC100490370, Xtro\cpb1, Xtro\cpa3, Xtro\cpb2" "Mmus\Cpa2, Mmus\Cpa6, Mmus\Cpb2, Mmus\Cpa4, Mmus\Cpa1, Mmus\Cpa3, Mmus\Cpb1, Mmus\Cpa5" "Hsap\CPA6, Hsap\CPA4, Hsap\CPA5, Hsap\CPA3, Hsap\CPO, Hsap\CPA2, Hsap\CPA1, Hsap\CPB2, Hsap\CPB1" viable FBgn0065606 l(2)SH0848 lethal (2) SH0848 http://flybase.org/reports/FBgn0065606 gene - - - "l(2)SH0848, l(2)SH2 0848" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261740 b6-22 - http://flybase.org/reports/FBgn0261740 gene - "regulation of development, heterochronic ; GO:0040034 | inferred from mutant phenotype" - b6-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - developmental rate defective FBgn0082960 snoRNA:Psi28S-3405a snoRNA:Psi28S-3405a http://flybase.org/reports/FBgn0082960 snoRNA_gene - - - "snoRNA:Psi28S-3405a, psi28s-3405a, Psi 28S-3405a, CR34618" - CR34618 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060419 l(3)S129114 lethal (3) S129114 http://flybase.org/reports/FBgn0060419 gene - - - "1291/14, l(3)S129114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266813 CR45275 - http://flybase.org/reports/FBgn0266813 non_protein_coding_gene - - - CR45275 - CR45275 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038579 CG14313 - http://flybase.org/reports/FBgn0038579 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14313 - CG14313 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264077 Cnx14D Calnexin 14D http://flybase.org/reports/FBgn0264077 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001580, InterPro:IPR009033, InterPro:IPR018124 unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001580 calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity" protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001580 protein folding ; GO:0006457 | inferred from sequence or structural similarity endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR001580 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity "Cnx, CG9906, Cnx14D, Xcbp1" "IPR001580:Calreticulin/calnexin, IPR009033:Calreticulin/calnexin, P domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR018124:Calreticulin/calnexin, conserved site" CG9906 11-Aug-17 DroID_v2017_08 "Drer\canx, Drer\si:ch211-274f20.2, Drer\calr, Drer\clgn" Scer\CNE1 "Cele\cnx-1, Cele\crt-1" "Xtro\calr, Xtro\canx" "Mmus\Calr, Mmus\Clgn, Mmus\Canx" "Hsap\CALR, Hsap\CANX, Hsap\CLGN" FBgn0065529 l(2)SH1112 lethal (2) SH1112 http://flybase.org/reports/FBgn0065529 gene - - - "l(2)SH1112, l(2)SH2 1112" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037950 HisCl1 Histamine-gated chloride channel subunit 1 http://flybase.org/reports/FBgn0037950 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 histamine-gated chloride channel activity ; GO:0019182 | inferred from direct assay thermotaxis ; GO:0043052 | inferred from mutant phenotype chloride transport ; GO:0006821 | inferred from direct assay histamine-gated chloride channel complex ; GO:0019183 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG14723, hclB, hisCl1, DmHisCl1, HisCl1, DMHisClalpha2, Dm-HCLB, HA-CI II, CT34515, HisCl-alpha2" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG14723 11-Aug-17 DroID_v2017_08 "Drer\gabrr2b, Drer\si:dkey-155h10.3, Drer\glra4a, Drer\LOC562831, Drer\glrbb, Drer\gabrr3a, Drer\glra2, Drer\gabrb3, Drer\gabrb1, Drer\gabrg2, Drer\LOC100001259, Drer\gabrp, Drer\gabra6b, Drer\gabrd, Drer\gabra6a, Drer\gabrr1, Drer\gabra1, Drer\glrba, Drer\gabrr2a, Drer\glra1, Drer\glra4b, Drer\glra3, Drer\si:dkey-52k1.6, Drer\zgc:110204, Drer\gabrb4, Drer\gabrb2, Drer\LOC100330554, Drer\gabra5" - "Cele\avr-14, Cele\gab-1, Cele\lgc-44, Cele\lgc-36, Cele\lgc-42, Cele\lgc-41, Cele\glc-3, Cele\lgc-40, Cele\lgc-39, Cele\lgc-45, Cele\lgc-37, Cele\ggr-1, Cele\glc-2, Cele\avr-15, Cele\lgc-38, Cele\unc-49, Cele\lgc-43, Cele\glc-4" "Xtro\gabrd, Xtro\gabra2, Xtro\glra2, Xtro\gabrg2, Xtro\LOC100490720, Xtro\gabra6, Xtro\gabrr3, Xtro\glrb, Xtro\glra3, Xtro\gabrp, Xtro\gabra5, Xtro\glra1, Xtro\gabrb3" "Mmus\Gabra5, Mmus\Gabrd, Mmus\Gabrq, Mmus\Gabrb1, Mmus\Gabrr2, Mmus\Gabra3, Mmus\Gabre, Mmus\Gabra1, Mmus\Glra2, Mmus\Gabrr1, Mmus\Gabra2, Mmus\Gabrg1, Mmus\Gabrr3, Mmus\Gabrg3, Mmus\Gabra6, Mmus\Gabrg2, Mmus\Gabrb2, Mmus\Gabrb3, Mmus\Glra3, Mmus\Glra4, Mmus\Gabrp, Mmus\Glrb, Mmus\Glra1" "Hsap\GABRP, Hsap\GABRB1, Hsap\GABRA1, Hsap\GABRB3, Hsap\GABRD, Hsap\GLRA1, Hsap\GLRA3, Hsap\GABRE, Hsap\GABRA5, Hsap\GABRR3, Hsap\GABRQ, Hsap\GABRR2, Hsap\GLRB, Hsap\GLRA2, Hsap\GABRA2, Hsap\GABRA6, Hsap\GABRG1, Hsap\GLRA4, Hsap\GABRR1, Hsap\GABRG3, Hsap\GABRB2, Hsap\GABRG2, Hsap\GABRA4" "chemical resistant,neurophysiology defective,paralytic,heat sensitive,chemical sensitive,partially lethal - majority die,some die during pupal stage,viable,thermotaxis behavior defective,recessive,lethal" FBgn0264711 CG43980 - http://flybase.org/reports/FBgn0264711 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "CG43980, CG33291, CG11250, CG33292" "IPR009072:Histone-fold, IPR000210:BTB/POZ domain, IPR002110:Ankyrin repeat, IPR011333:SKP1/BTB/POZ domain, IPR020683:Ankyrin repeat-containing domain" CG43980 11-Aug-17 DroID_v2017_08 "Drer\btbd11a, Drer\btbd11b, Drer\abtb2b, Drer\abtb2a" - - "Xtro\abtb2, Xtro\btbd11" "Mmus\Btbd11, Mmus\Abtb2" "Hsap\ABTB2, Hsap\BTBD11" DRSC11500 E 0.174452997 0.294712213 2.434766404 0.083883545 0.39343533 -0.528620544 FBgn0265154 Ir60f Ionotropic receptor 60f http://flybase.org/reports/FBgn0265154 pseudogene_attribute - - - "Ir60f, DmelIR60f, CR44223" - CR44223 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265686 CR44493 - http://flybase.org/reports/FBgn0265686 non_protein_coding_gene - - - CR44493 - CR44493 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027782 Su(y)P22 Su(y)P22 http://flybase.org/reports/FBgn0027782 - gene - - - "Su(y)[P22], Su(y)P22" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037126 CG14567 - http://flybase.org/reports/FBgn0037126 protein_coding_gene - - - CG14567 - CG14567 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0243498 l(2)CA07436 - http://flybase.org/reports/FBgn0243498 gene - - - l(2)CA07436 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0266771 CR45236 - http://flybase.org/reports/FBgn0266771 non_protein_coding_gene - - - CR45236 - CR45236 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031299 CG4629 - http://flybase.org/reports/FBgn0031299 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678822" regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 cell adhesion ; GO:0007155 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 "anon-WO0257455.15, CG4629" "IPR011009:Protein kinase-like domain, IPR008271:Serine/threonine-protein kinase, active site, IPR000719:Protein kinase domain, IPR017441:Protein kinase, ATP binding site" CG4629 11-Aug-17 DroID_v2017_08 "Drer\LOC100333844, Drer\nim1k, Drer\si:ch211-22d5.2" "Scer\PTK1, Scer\SNF1, Scer\PTK2" Cele\F49C5.4 Xtro\nim1k Mmus\Nim1k Hsap\NIM1K viable FBgn0034360 CG10927 - http://flybase.org/reports/FBgn0034360 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR016193 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002125 - - CG10927 "IPR002125:Cytidine and deoxycytidylate deaminases, zinc-binding, IPR016193:Cytidine deaminase-like" CG10927 11-Aug-17 DroID_v2017_08 Drer\adat3 Scer\TAD3 "Cele\T24A6.7, Cele\Y47D3A.14, Cele\C08E8.4, Cele\C37C3.1, Cele\irg-1" - "Mmus\Adat3, Mmus\Scamp4" Hsap\ADAT3 viable FBgn0028096 l(3)S074606b lethal (3) S074606b http://flybase.org/reports/FBgn0028096 gene - - - "0746/06, l(3)S074606, l(3)S074606b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030163 CG1791 - http://flybase.org/reports/FBgn0030163 protein_coding_gene transmembrane receptor protein tyrosine kinase activator activity ; GO:0030297 | inferred from sequence or structural similarity with HGNC:487 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with HGNC:487 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:487 "CG1791, AAM52597, AAF46535, FBpp0071364" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG1791 11-Aug-17 DroID_v2017_08 "Drer\angpt1, Drer\fibcd1, Drer\angptl2b, Drer\angptl5, Drer\angptl2a, Drer\si:zfos-2330d3.3, Drer\wu:fj11g02, Drer\si:ch1073-110a20.3, Drer\si:ch211-203k16.3, Drer\si:zfos-2330d3.6, Drer\si:ch1073-110a20.2, Drer\tnxba, Drer\fgl2a, Drer\tnc, Drer\angptl4, Drer\zmp:0000000846, Drer\fga, Drer\si:zfos-2330d3.8, Drer\LOC555374, Drer\angpt2b, Drer\si:zfos-2330d3.1, Drer\zgc:173915, Drer\mfap4, Drer\angpt2a, Drer\tnr, Drer\zgc:194887, Drer\angptl3, Drer\LOC100007488, Drer\si:dkeyp-51b7.3, Drer\angptl1a, Drer\si:ch211-287a12.9, Drer\angpt4, Drer\fgb, Drer\angptl6, Drer\fgl2b, Drer\tnw, Drer\si:ch211-157b11.8, Drer\fgg, Drer\angptl7, Drer\si:ch1073-110a20.1, Drer\fgl1, Drer\zgc:171687" - "Cele\Y26D4A.12, Cele\C08G9.2, Cele\let-805, Cele\ensh-1, Cele\ZC504.1, Cele\eea-1, Cele\T15B7.1, Cele\Y69H2.10, Cele\Y69H2.3, Cele\K10D3.4, Cele\Y43C5A.2, Cele\W05B2.2, Cele\C18E9.7" "Xtro\angpt1, Xtro\fga, Xtro\angpt4, Xtro\fgl2, Xtro\fcn3, Xtro\LOC100491105, Xtro\angptl3, Xtro\fcn2, Xtro\fgl1, Xtro\tnr, Xtro\tnc, Xtro\mfap4, Xtro\fgg, Xtro\LOC100488177, Xtro\tnn, Xtro\angptl4, Xtro\fibcd1, Xtro\fgb, Xtro\LOC100497330, Xtro\angptl5, Xtro\fcn1, Xtro\tnxb, Xtro\angptl2" "Mmus\Angptl2, Mmus\Tnc, Mmus\Fga, Mmus\Angptl1, Mmus\Mfap4, Mmus\Fcna, Mmus\Angpt1, Mmus\Tnn, Mmus\Fgl1, Mmus\Angptl7, Mmus\Fcnb, Mmus\Fgl2, Mmus\Tnxb, Mmus\Angptl3, Mmus\Fgg, Mmus\Tnr, Mmus\Angptl6, Mmus\Angptl4, Mmus\Fibcd1, Mmus\Fgb, Mmus\Angpt4, Mmus\Angpt2" "Hsap\FCN2, Hsap\ANGPTL6, Hsap\FIBCD1, Hsap\FCN3, Hsap\TNXB, Hsap\FGL1, Hsap\MFAP4, Hsap\TNR, Hsap\ANGPTL7, Hsap\ANGPTL5, Hsap\ANGPT4, Hsap\TNN, Hsap\ANGPTL2, Hsap\FCN1, Hsap\ANGPTL4, Hsap\TNC, Hsap\FGA, Hsap\FGB, Hsap\FGG, Hsap\ANGPTL1, Hsap\FGL2, Hsap\ANGPT2, Hsap\ANGPT1, Hsap\ANGPTL3" viable DRSC29301 K -0.094167122 -0.129779061 0.387101592 -0.108230934 -0.523416556 3.118458144 FBgn0034467 CG15128 - http://flybase.org/reports/FBgn0034467 protein_coding_gene - - - CG15128 "IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR011990:Tetratricopeptide-like helical domain" CG15128 11-Aug-17 DroID_v2017_08 - - - - - Hsap\TTC25 viable FBgn0027190 l(2)60A-B lethal (2) 60A-B http://flybase.org/reports/FBgn0027190 - gene - - - l(2)60A-B - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002276 l(3)73Aa lethal (3) 73Aa http://flybase.org/reports/FBgn0002276 - gene - - - "l(3)std6, l(3)73Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261287 ymp yellow-emperor http://flybase.org/reports/FBgn0261287 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "ymp, BcDNA:AT03213, CG12250" - CG12250 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026326 Mad1 Mitotic arrest-deficient 1 http://flybase.org/reports/FBgn0026326 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype attachment of mitotic spindle microtubules to kinetochore ; GO:0051315 | inferred from mutant phenotype nuclear envelope ; GO:0005635 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay mitotic spindle ; GO:0072686 | colocalizes_with inferred from direct assay "CG2072, Mad1, TXBP181-like, mad1" IPR008672:Spindle assembly checkpoint component Mad1 CG2072 11-Aug-17 DroID_v2017_08 Drer\mad1l1 Scer\MAD1 Cele\mdf-1 "Xtro\pibf1, Xtro\mad1l1" Mmus\Mad1l1 Hsap\MAD1L1 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0033751 CG8818 - http://flybase.org/reports/FBgn0033751 protein_coding_gene - - - CG8818 - CG8818 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0086386 BG01672 - http://flybase.org/reports/FBgn0086386 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01672 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0001590 l(1)carot7 lethal (1) carot7 http://flybase.org/reports/FBgn0001590 - gene - - - l(1)carot7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035632 Ppat-Dpck Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase http://flybase.org/reports/FBgn0035632 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001977 dephospho-CoA kinase activity ; GO:0004140 | inferred from biological aspect of ancestor with PANTHER:PTN000075336 pantetheine-phosphate adenylyltransferase activity ; GO:0004595 | inferred from sequence alignment with MGI:MGI:1918993 dephospho-CoA kinase activity ; GO:0004140 | inferred from sequence alignment with MGI:MGI:1918993 "ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype coenzyme A biosynthetic process ; GO:0015937 | inferred from sequence alignment with MGI:MGI:1918993 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype coenzyme A biosynthetic process ; GO:0015937 | inferred from biological aspect of ancestor with PANTHER:PTN000075336 triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype" - "CG10575, DPCK/PPAT, Ppat-Dpck, PPAT-DPCK, dPPAT-DPCK, dCOASY" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001977:Dephospho-CoA kinase, IPR004821:Cytidyltransferase-like domain, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG10575 11-Aug-17 DroID_v2017_08 "Drer\dcakd, Drer\coasy" "Scer\CAB5, Scer\CAB4" Cele\Y65B4A.8 "Xtro\coasy, Xtro\dcakd" "Mmus\Coasy, Mmus\Dcakd" "Hsap\DCAKD, Hsap\COASY" "locomotor behavior defective,paralytic,heat sensitive,female sterile,partially,recessive,flightless,flight defective,short lived,visible,chemical sensitive,radiation sensitive,increased cell death,sterile,viable" "wing,embryonic/larval brain,wing vein,ectopic,egg,maternal effect,egg chamber,follicle cell,lipid droplet & egg chamber" FBgn0070014 BG01130 BG01130 http://flybase.org/reports/FBgn0070014 gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - BG01130 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,behavior defective,recessive" FBgn0034700 CG11269 - http://flybase.org/reports/FBgn0034700 protein_coding_gene endoribonuclease activity ; GO:0004521 | inferred from biological aspect of ancestor with PANTHER:PTN002421559 rRNA transcription ; GO:0009303 | inferred from biological aspect of ancestor with PANTHER:PTN002421559 - CG11269 IPR026770:Ribonuclease kappa CG11269 11-Aug-17 DroID_v2017_08 "Drer\rnasekb, Drer\rnaseka" Scer\YPR170W-B "Cele\F49C12.12, Cele\C46G7.1" Xtro\rnasek Mmus\Rnasek Hsap\RNASEK viable FBgn0015968 l(2)55BCa lethal (2) 55BCa http://flybase.org/reports/FBgn0015968 - gene - - - l(2)55BCa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266909 CR45369 - http://flybase.org/reports/FBgn0266909 non_protein_coding_gene - - - CR45369 - CR45369 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030658 CG7872 - http://flybase.org/reports/FBgn0030658 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available endomembrane system ; GO:0012505 | inferred from direct assay CG7872 "IPR001623:DnaJ domain, IPR018253:DnaJ domain, conserved site" CG7872 11-Aug-17 DroID_v2017_08 Drer\dnajc25 - "Cele\dnj-2, Cele\C47A4.1" Xtro\dnajc25 Mmus\Dnajc25 "Hsap\DNAJC25, Hsap\DNAJC25-GNG10" "viable,fertile" FBgn0046842 ird26 immune response deficient 26 http://flybase.org/reports/FBgn0046842 gene molecular_function ; GO:0003674 | no biological data available humoral immune response ; GO:0006959 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ird26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,immune response defective" FBgn0261986 RASSF8 Ras association domain family member 8 http://flybase.org/reports/FBgn0261986 protein_coding_gene - signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000159 negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype adherens junction ; GO:0005912 | inferred from direct assay "dmRASSF7/8, CG5053, dRASSF8, RASSF8, Boa" "IPR029071:Ubiquitin-related domain, IPR000159:Ras-associating (RA) domain, IPR033593:N-terminal RASSF family" CG5053 11-Aug-17 DroID_v2017_08 "Drer\rassf9, Drer\LOC100003291, Drer\rassf8b, Drer\rassf7a, Drer\rassf7b" - Cele\K05B2.2 "Xtro\rassf7, Xtro\rassf9, Xtro\rassf10, Xtro\rassf8" "Mmus\Rassf7, Mmus\Rassf8, Mmus\Rassf9" "Hsap\RASSF9, Hsap\RASSF7, Hsap\RASSF8" FBgn0022231 l(2)k03003 lethal (2) k03003 http://flybase.org/reports/FBgn0022231 - gene - - - l(2)k03003 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261536 CG42660 - http://flybase.org/reports/FBgn0261536 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42660 - CG42660 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016895 l(3)64Ce lethal (3) 64Ce http://flybase.org/reports/FBgn0016895 - gene - - - l(3)64Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263402 CG43448 - http://flybase.org/reports/FBgn0263402 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43448, lincRNA.898" - CG43448 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0284435 tyn trynity http://flybase.org/reports/FBgn0284435 protein_coding_gene molecular_function ; GO:0003674 | no biological data available actin filament organization ; GO:0007015 | inferred from mutant phenotype apical constriction ; GO:0003383 | inferred from mutant phenotype cell-matrix adhesion ; GO:0007160 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay "CG17131, tyn, CG17131-ORFA, CG17131-ORFB, SP71, EP(X)1421, P277, EP1421, l(1)G0259" "IPR003609:PAN/Apple domain, IPR001507:Zona pellucida domain" CG17131 11-Aug-17 DroID_v2017_08 - - "Cele\ZC449.1, Cele\cutl-17, Cele\noah-2, Cele\noah-1, Cele\ZC449.2, Cele\F52C9.5, Cele\R07A4.4, Cele\T23F1.5, Cele\C16D9.1, Cele\let-653, Cele\cutl-28, Cele\cutl-18, Cele\H42K12.3, Cele\H03E18.1, Cele\T26C5.2, Cele\cutl-15, Cele\cutl-27, Cele\F32B4.8, Cele\C34C12.7, Cele\cutl-23, Cele\cut-6, Cele\cutl-14" - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028534 CG7916 - http://flybase.org/reports/FBgn0028534 protein_coding_gene - - - "CT23894, BG:DS00941.13, CG7916, LP05416" IPR010562:Haemolymph juvenile hormone binding CG7916 11-Aug-17 DroID_v2017_08 - - Cele\fbxa-14 - - - viable FBgn0051851 Naa20B N(alpha)-acetyltransferase 20 B http://flybase.org/reports/FBgn0051851 protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from biological aspect of ancestor with PANTHER:PTN000558065 N-terminal peptidyl-methionine acetylation ; GO:0017196 | inferred from biological aspect of ancestor with PANTHER:PTN000558099 NatB complex ; GO:0031416 | inferred from biological aspect of ancestor with PANTHER:PTN000558099 "CG16821, Naa20B, Naa20, CG31851" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG31851 11-Aug-17 DroID_v2017_08 Drer\naa20 Scer\NAT3 Cele\Y97E10AL.3 - Mmus\Naa20 Hsap\NAA20 "viable,fertile" FBgn0062440 CG17680 - http://flybase.org/reports/FBgn0062440 protein_coding_gene - calcium ion transmembrane import into mitochondrion ; GO:0036444 | inferred from electronic annotation with InterPro:IPR018782 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype mitochondrial calcium ion transport ; GO:0006851 | inferred from mutant phenotype mitochondrial calcium ion homeostasis ; GO:0051560 | inferred from mutant phenotype uniplex complex ; GO:1990246 | inferred from electronic annotation with InterPro:IPR018782 "BcDNA:RE55001, CG17680, EMRE" "IPR018782:Essential MCU regulator, mitochondrial" CG17680 11-Aug-17 DroID_v2017_08 Drer\smdt1b - Cele\emre-1 Xtro\smdt1 Mmus\Smdt1 Hsap\SMDT1 "lethal,body color defective" mesothoracic tergum FBgn0001439 l(1)7Ca lethal (1) 7Ca http://flybase.org/reports/FBgn0001439 - gene - - - l(1)7Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0001587 l(1)carot4 lethal (1) carot4 http://flybase.org/reports/FBgn0001587 - gene - - - l(1)carot4 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034865 Or59b Odorant receptor 59b http://flybase.org/reports/FBgn0034865 protein_coding_gene olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "59b, DOR119, 59E.1, CG3569, Or59b, DmOR59B" "IPR004117:Olfactory receptor, insect" CG3569 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0039584 beat-VI beat-VI http://flybase.org/reports/FBgn0039584 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic anchored component of membrane ; GO:0031225 | inferred from sequence model "beat VI, CG12089, CG14064, beat-VI, Beat-VI, beat" "IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold" CG14064 11-Aug-17 DroID_v2017_08 "Drer\zgc:172120, Drer\LOC797620, Drer\zgc:172106, Drer\zgc:153911, Drer\si:dkey-71p21.13, Drer\cd276" - - "Xtro\f11r, Xtro\clmp, Xtro\esam" - "Hsap\F11R, Hsap\CADM2" viable FBgn0026612 A69 A69 http://flybase.org/reports/FBgn0026612 - gene - - - A69 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032287 CG6415 - http://flybase.org/reports/FBgn0032287 protein_coding_gene aminomethyltransferase activity ; GO:0004047 | inferred from sequence or structural similarity with UniProtKB:P48728 glycine catabolic process ; GO:0006546 | inferred from sequence or structural similarity with UniProtKB:P48728 lipid particle ; GO:0005811 | inferred from direct assay glycine cleavage complex ; GO:0005960 | inferred from sequence or structural similarity with UniProtKB:P48728 "151967_at, anon-32Aa, CG6415" "IPR006222:Glycine cleavage T-protein-like, N-terminal, IPR006223:Glycine cleavage system T protein, IPR013977:Glycine cleavage T-protein, C-terminal barrel domain, IPR028896:Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA, IPR029043:Glycine cleavage T-protein/YgfZ, C-terminal domain" CG6415 11-Aug-17 DroID_v2017_08 Drer\amt Scer\GCV1 "Cele\gcst-1, Cele\M04B2.4" Xtro\amt Mmus\Amt Hsap\AMT FBgn0019803 l(1)01 lethal (1) 01 http://flybase.org/reports/FBgn0019803 - gene - - - l(1)01 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0043368 EP1523 EP1523 http://flybase.org/reports/FBgn0043368 gene - - - EP1523 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "scutellar bristle,ectopic" FBgn0004832 Xpac Xeroderma pigmentosum group A-like http://flybase.org/reports/FBgn0004832 - protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000015717 "nucleotide-excision repair ; GO:0006289 | inferred from direct assay inferred from genetic interaction with HGNC:12814 UV-damage excision repair ; GO:0070914 | inferred from biological aspect of ancestor with PANTHER:PTN000015717 nucleotide-excision repair, DNA damage recognition ; GO:0000715 | inferred from biological aspect of ancestor with PANTHER:PTN000015717 base-excision repair ; GO:0006284 | inferred from biological aspect of ancestor with PANTHER:PTN000015717 nucleotide-excision repair involved in interstrand cross-link repair ; GO:1901255 | inferred from biological aspect of ancestor with PANTHER:PTN000015717 nucleotide-excision repair, DNA incision ; GO:0033683 | inferred from biological aspect of ancestor with PANTHER:PTN000015717" nucleotide-excision repair factor 1 complex ; GO:0000110 | inferred from biological aspect of ancestor with PANTHER:PTN000015717 nucleus ; GO:0005634 | inferred from direct assay "Xpa, dxpa, XPAC, Dxpa, DhXPA, DhR14, DmXPA, dmXPA, EG:EG0007.8, CG6358, Xpac, XPA_DROME" "IPR000465:XPA, IPR009061:Putative DNA-binding domain, IPR022652:Zinc finger, XPA-type, conserved site, IPR022656:XPA C- terminal, IPR022658:XPA, conserved site" CG6358 11-Aug-17 DroID_v2017_08 Drer\xpa Scer\RAD14 Cele\xpa-1 Xtro\xpa Mmus\Xpa Hsap\XPA " embryonic stage , adult stage , pupal stage | mid , larval stage | third instar , pupal stage | early " " adult stage , embryonic stage " " muscle cell

, lamina

, retina

, adult central nervous system

, ventral nerve cord

" viable FBgn0003962 us undersized http://flybase.org/reports/FBgn0003962 - gene - - - us - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile" FBgn0035847 mthl7 methuselah-like 7 http://flybase.org/reports/FBgn0035847 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "CG7476, anon-WO0170980.85, anon-WO0170980.86, mthl7" "IPR017981:GPCR, family 2-like, IPR010596:Methuselah, N-terminal domain, IPR023311:Methuselah ectodomain, domain 2" CG7476 11-Aug-17 DroID_v2017_08 "Drer\adgrg6, Drer\adgrf11" - Cele\lat-2 Xtro\gpr157 Mmus\Adgre1 - viable FBgn0036219 CCDC151 Coiled-coil domain containing protein 151 http://flybase.org/reports/FBgn0036219 protein_coding_gene molecular_function ; GO:0003674 | no biological data available axonemal dynein complex assembly ; GO:0070286 | inferred from sequence or structural similarity with UniProtKB:F1QFD6 negative gravitaxis ; GO:0048060 | inferred from mutant phenotype cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:F1QFD6 outer dynein arm assembly ; GO:0036158 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 cilium movement ; GO:0003341 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 ciliary rootlet ; GO:0035253 | inferred from direct assay cell body ; GO:0044297 | inferred from direct assay motile cilium ; GO:0031514 | inferred from direct assay ciliary tip ; GO:0097542 | inferred from direct assay axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 "CG14127, CCDC151" - CG14127 11-Aug-17 DroID_v2017_08 Drer\ccdc151 - - Xtro\ccdc151 "Mmus\Ccdc151, Mmus\Ccdc183" "Hsap\CCDC183, Hsap\CCDC151" "bang sensitive,gravitaxis defective,viable" FBgn0053392 5SrRNA:CR33392 5SrRNA:CR33392 http://flybase.org/reports/FBgn0053392 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33392, 5SrRNA:CR33392" - CR33392 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053257 CG33257 - http://flybase.org/reports/FBgn0053257 protein_coding_gene molecular_function ; GO:0003674 | no biological data available developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 cellular_component ; GO:0005575 | no biological data available "CG13037, CG33257" IPR007999:Protein of unknown function DUF745 CG33257 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065687 l(2)SH0650 lethal (2) SH0650 http://flybase.org/reports/FBgn0065687 gene - - - "l(2)SH0650, l(2)SH2 0650" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265759 CR44566 - http://flybase.org/reports/FBgn0265759 non_protein_coding_gene - - - "CR44566, lincRNA.591" - CR44566 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033596 CG7738 - http://flybase.org/reports/FBgn0033596 protein_coding_gene - - - "CG7738, BcDNA:RH51528" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002663 mat(2)cell-L maternal effect cellularisation defect L http://flybase.org/reports/FBgn0002663 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)cellRQ41, mat(2)cell-L" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" "stage 5 embryo,embryonic/first instar larval cuticle" FBgn0085340 CR34311 - http://flybase.org/reports/FBgn0085340 pseudogene_attribute - - - CR34311 - CR34311 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019679 mor(1)12 mortality gene (1)12 http://flybase.org/reports/FBgn0019679 - gene - - - mor(1)12 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0262730 dtn detonator http://flybase.org/reports/FBgn0262730 protein_coding_gene - detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001780530 "MRE2, lincRNA.S8753, CG14446, dtn" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR026307:Transmembrane protein 132, IPR031437:Transmembrane protein family 132, middle domain, IPR031436:Transmembrane protein TMEM132, C-terminal, IPR031435:Transmembrane protein TMEM132, N-terminal" CG14446 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-14d3.1, Drer\tmem132e, Drer\tmem132a, Drer\si:dkey-112m2.1, Drer\si:dkey-1d7.3, Drer\si:dkey-215k6.1" - Cele\Y71H2AM.10 "Xtro\tmem132d, Xtro\tmem132c, Xtro\tmem132e, Xtro\tmem132a" "Mmus\Tmem132d, Mmus\Tmem132e, Mmus\Tmem132a, Mmus\Tmem132c, Mmus\Tmem132b" "Hsap\TMEM132C, Hsap\TMEM132A, Hsap\TMEM132D, Hsap\TMEM132B, Hsap\TMEM132E" FBgn0010220 Dbp45A DEAD box protein 45A http://flybase.org/reports/FBgn0010220 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000001212 "RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0000381 "DBP45A, DmRH18, dbp45A, Dbp45, CG12759, Dbp45A" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12759 11-Aug-17 DroID_v2017_08 Drer\ddx49 Scer\DBP8 Cele\H20J04.4 Xtro\ddx49 Mmus\Ddx49 Hsap\DDX49 embryonic stage -- adult stage "viable,visible" "trichogen cell,mesothoracic tergum" DRSC07395 I -1.509884774 0.827415492 -0.432689055 -0.380810194 0.449817345 0.564759769 FBgn0003874 tu(1)53 tumor(1)53 http://flybase.org/reports/FBgn0003874 - gene - - - "tu-53l, tu(1)53" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,partially lethal - majority die,developmental rate defective" wing FBgn0041256 E(csw)3B E(csw)3B http://flybase.org/reports/FBgn0041256 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available E(csw)3B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031351 CG14352 - http://flybase.org/reports/FBgn0031351 protein_coding_gene - - - CG14352 IPR028002:Myb/SANT-like DNA-binding domain CG14352 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031182 Cyp6t1 Cyp6t1 http://flybase.org/reports/FBgn0031182 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CG1644, Cyp6t1, 6t1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG1644 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp3c4, Drer\cyp3c1, Drer\cyp3c3, Drer\cyp3c2, Drer\tbxas1" Scer\ERG11 "Cele\cyp-13A2, Cele\cyp-13A11, Cele\cyp-13B1, Cele\cyp-13A8, Cele\cyp-13A12, Cele\cyp-25A3, Cele\cyp-25A2, Cele\cyp-13A4, Cele\cyp-25A4, Cele\cyp-13A6, Cele\cyp-13A3, Cele\cyp-43A1, Cele\cyp-13A5, Cele\cyp-44A1, Cele\cyp-25A1, Cele\cyp-13B2, Cele\cyp-25A6, Cele\cyp-13A7, Cele\cyp-13A1, Cele\cyp-13A10" "Xtro\cyp3a5, Xtro\cyp3a4, Xtro\tbxas1, Xtro\LOC100494419" "Mmus\Cyp3a16, Mmus\Cyp3a57, Mmus\Cyp3a41b, Mmus\Cyp3a11, Mmus\Cyp3a41a, Mmus\Cyp3a59, Mmus\Cyp3a25, Mmus\Tbxas1, Mmus\Cyp3a13, Mmus\Cyp3a44" "Hsap\CYP3A5, Hsap\CYP3A4, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A7, Hsap\CYP3A43, Hsap\TBXAS1" "viable,fertile" FBgn0028686 Rpt3 Regulatory particle triple-A ATPase 3 http://flybase.org/reports/FBgn0028686 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001270, InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | inferred from sequence model proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "male germ cell nucleus ; GO:0001673 | inferred from direct assay nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9551 inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000002802" "p48A, Dm_Rpt3a, Dmp48A, l(1)G0052, CG16916, Rpt3, 16916, TBP7, S6B, S6" "IPR001270:ClpA/B family, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG16916 11-Aug-17 DroID_v2017_08 "Drer\psmc1a, Drer\psmc4" Scer\RPT3 "Cele\C10G11.8, Cele\rpt-3, Cele\rpt-2" "Xtro\psmc4, Xtro\psmc1" "Mmus\Psmc4, Mmus\Psmc1" "Hsap\PSMC4, Hsap\PSMC1" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" DRSC20283 IEK -3.267273407 -3.960803336 -3.571212589 -3.382874364 0.764042517 -1.693399715 FBgn0042173 CG18853 - http://flybase.org/reports/FBgn0042173 protein_coding_gene deoxyribodipyrimidine photo-lyase activity ; GO:0003904 | inferred from biological aspect of ancestor with PANTHER:PTN000025285 photoreactive repair ; GO:0000719 | inferred from biological aspect of ancestor with PANTHER:PTN000025285 - "143303_at, CG18853, CG18853-PA" "IPR005101:Cryptochrome/DNA photolyase, FAD-binding domain, IPR032673:DNA photolyase class 2, conserved site, IPR023370:TsaA-like domain" CG18853 11-Aug-17 DroID_v2017_08 "Drer\cry1aa, Drer\cry1ab, Drer\cry1bb, Drer\cry1ba, Drer\trmo, Drer\cry-dash, Drer\zgc:66475, Drer\cry4, Drer\cry5, Drer\si:ch1073-390k14.1" Scer\PHR1 - "Xtro\cry2, Xtro\cry1, Xtro\cry4" "Mmus\Trmo, Mmus\Cry1, Mmus\Cry2" "Hsap\TRMO, Hsap\CRY2, Hsap\CRY1" "viable,fertile" DRSC20757 K -0.87766115 0.463158151 0.492163446 -0.752932001 -1.920071978 -1.708189136 FBgn0027978 l(3)S138815 lethal (3) S138815 http://flybase.org/reports/FBgn0027978 gene - - - "1388/15, l(3)S138815" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037910 CG14708 - http://flybase.org/reports/FBgn0037910 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14708 - CG14708 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266629 CR45136 - http://flybase.org/reports/FBgn0266629 non_protein_coding_gene - - - CR45136 - CR45136 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265318 CR44291 - http://flybase.org/reports/FBgn0265318 non_protein_coding_gene - - - CR44291 - CR44291 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033243 CG14763 - http://flybase.org/reports/FBgn0033243 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity CG14763 IPR005334:Tctex-1 CG14763 11-Aug-17 DroID_v2017_08 "Drer\tctex1d2, Drer\tctex1d1, Drer\tctex1d4" - Cele\dylt-2 Xtro\tctex1d1 "Mmus\Tctex1d4, Mmus\Tctex1d2, Mmus\Gm3448, Mmus\Gm3417, Mmus\Tcte3, Mmus\Tctex1d1" "Hsap\TCTEX1D2, Hsap\TCTEX1D4, Hsap\TCTEX1D1, Hsap\TCTE3" viable FBgn0035780 CG18417 - http://flybase.org/reports/FBgn0035780 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "CG18417, carboxypeptidase b1" "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG18417 11-Aug-17 DroID_v2017_08 "Drer\cpa4, Drer\cpa5, Drer\cpb1, Drer\cpa2, Drer\cpb2, Drer\cpa1, Drer\cpa6, Drer\cpo" Scer\ECM14 "Cele\Y59C2A.1, Cele\F02D8.4, Cele\T06A4.3, Cele\W01A8.6, Cele\Y18H1A.9, Cele\T06A4.1, Cele\ZC434.9, Cele\suro-1, Cele\Y47G6A.19" "Xtro\cpo, Xtro\cpb1, Xtro\cpa3, Xtro\cpa1, Xtro\cpb2" "Mmus\Cpa1, Mmus\Cpa2, Mmus\Cpa4, Mmus\Cpa3, Mmus\Cpb2, Mmus\Cpa5, Mmus\Cpb1, Mmus\Cpa6" "Hsap\CPA1, Hsap\CPA3, Hsap\CPA4, Hsap\CPA5, Hsap\CPA6, Hsap\CPB2, Hsap\CPB1, Hsap\CPO, Hsap\CPA2" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0044862 MMS-6 MMS-6 http://flybase.org/reports/FBgn0044862 gene - - - MMS-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0024235 fs(1)513 fs(1)513 http://flybase.org/reports/FBgn0024235 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available fs(1)513 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg chamber,stage S7 oocyte,nurse cell" FBgn0053461 CG33461 - http://flybase.org/reports/FBgn0053461 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 proteolysis ; GO:0006508 | inferred from sequence model" - "SP41, CG8215, CG30086, CG33461" "IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR001254:Serine proteases, trypsin domain" CG33461 11-Aug-17 DroID_v2017_08 - - Cele\try-3 - Mmus\Egfbp2 - DRSC22892 K -0.963308304 0.695166571 0.025626953 -0.551202839 0.922651279 1.784772587 FBgn0022746 anon-H2 anon-H2 http://flybase.org/reports/FBgn0022746 - gene - - - "H2, anon-H2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002130 l(2)K203 lethal (2) K203 http://flybase.org/reports/FBgn0002130 - gene - - - l(2)K203 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052693 Gr9a Gustatory receptor 9a http://flybase.org/reports/FBgn0052693 protein_coding_gene taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity with Gr5a detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from sequence or structural similarity with Gr5a integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | inferred from sequence model "CG32693, Gr9a, GR9a" IPR013604:7TM chemoreceptor CG32693 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053280 CG33280 - http://flybase.org/reports/FBgn0053280 protein_coding_gene - - - CG33280 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040703 CG12494 - http://flybase.org/reports/FBgn0040703 protein_coding_gene - - - CG12494 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015540 scs' special chromatin structure' http://flybase.org/reports/FBgn0015540 - insulator - - - "scs', SCS'" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052944 CG32944 - http://flybase.org/reports/FBgn0052944 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000683254" peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 actin filament organization ; GO:0007015 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 "CG9818, CG10532, CG32944" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG32944 11-Aug-17 DroID_v2017_08 "Drer\rps6kal, Drer\akt3a, Drer\LOC100331306, Drer\rps6kb1a, Drer\akt2, Drer\stk32a, Drer\sgk2a, Drer\rps6ka1, Drer\akt3b, Drer\sgk1, Drer\sgk3, Drer\si:ch211-195b13.1, Drer\rps6ka2, Drer\rps6ka3a, Drer\sgk2b, Drer\rps6kb1b, Drer\rps6ka4, Drer\rps6ka3b, Drer\rps6ka5" "Scer\DBF20, Scer\YPK1, Scer\YPK3, Scer\YPK2, Scer\SCH9, Scer\RIM15, Scer\DBF2" "Cele\M03C11.1, Cele\sel-5" "Xtro\stk32b, Xtro\sgk1, Xtro\rps6kb1, Xtro\rps6ka4, Xtro\sgk2, Xtro\akt1, Xtro\stk32a, Xtro\akt2, Xtro\rps6ka1, Xtro\rps6ka6, Xtro\rps6ka3, Xtro\rps6ka2" "Mmus\Stk32c, Mmus\Stk32a, Mmus\Sgk1, Mmus\Rps6kb1, Mmus\Akt3, Mmus\Stk32b, Mmus\Rps6ka1, Mmus\Rps6ka4, Mmus\Rps6ka6, Mmus\Sgk3, Mmus\Akt1, Mmus\Rps6ka2, Mmus\Rps6ka3, Mmus\Rps6kb2, Mmus\Akt2, Mmus\Sgk2" "Hsap\RPS6KA4, Hsap\RPS6KA5, Hsap\RPS6KB1, Hsap\SGK3, Hsap\STK32B, Hsap\AKT1, Hsap\SGK1, Hsap\RPS6KA3, Hsap\SGK2, Hsap\STK32A, Hsap\AKT2, Hsap\RPS6KA6, Hsap\STK32C, Hsap\RPS6KA1, Hsap\AKT3, Hsap\RPS6KB2, Hsap\MAP4K5, Hsap\RPS6KA2" "viable,fertile" DRSC12341 E -0.275653851 -0.608386977 -1.804873754 0.080624562 -0.012839207 0.003319323 FBgn0011203 boc bocce http://flybase.org/reports/FBgn0011203 - gene - primary spermatocyte growth ; GO:0007285 | inferred from mutant phenotype - "ms(2)boc, ms(2)02530, boc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female semi-sterile" "testis,primary spermatocyte cyst" FBgn0032483 CG15482 - http://flybase.org/reports/FBgn0032483 protein_coding_gene - - - CG15482 IPR031732:Protein of unknown function DUF4729 CG15482 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043060 Tl::Tollo Tl::Tollo http://flybase.org/reports/FBgn0043060 engineered_fusion_gene - - - Tl::Tollo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033337 CG8272 - http://flybase.org/reports/FBgn0033337 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CT8327, CG8272, FBXL9" "IPR001810:F-box domain, IPR006553:Leucine-rich repeat, cysteine-containing subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG8272 11-Aug-17 DroID_v2017_08 Drer\lrrc29 Scer\GRR1 Cele\EEED8.10 - "Mmus\Usp26, Mmus\Lrrc29" "Hsap\LRRC29, Hsap\AK8, Hsap\USP29, Hsap\USP26" viable FBgn0042642 fof failure to fuse http://flybase.org/reports/FBgn0042642 gene - - - fof - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028429 I-2 Inhibitor-2 http://flybase.org/reports/FBgn0028429 protein_coding_gene protein phosphatase inhibitor activity ; GO:0004864 | inferred from mutant phenotype protein phosphatase inhibitor activity ; GO:0004864 | inferred from direct assay protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B regulation of signal transduction ; GO:0009966 | inferred from electronic annotation with InterPro:IPR007062 negative regulation of protein dephosphorylation ; GO:0035308 | inferred from mutant phenotype regulation of phosphoprotein phosphatase activity ; GO:0043666 | inferred from biological aspect of ancestor with PANTHER:PTN000273866 negative regulation of protein dephosphorylation ; GO:0035308 | inferred from direct assay protein phosphatase type 1 complex ; GO:0000164 | colocalizes_with inferred from direct assay "I-2, CG10574, I-2Dm, Dm I-2, I-2PP1, SET, DI-2" IPR007062:Protein phosphatase inhibitor 2 (IPP-2) CG10574 11-Aug-17 DroID_v2017_08 Drer\ppp1r2 Scer\GLC8 Cele\szy-2 Xtro\ppp1r2 "Mmus\Ppp1r2, Mmus\2810408A11Rik" Hsap\PPP1R2 " embryonic stage | 0-24 hr , adult stage , pupal stage , adult stage | male , larval stage , embryonic stage | early , spermatogenesis && adult stage , embryonic stage , adult stage | female " " adult head

, larval brain

, imaginal disc

, spermatocyte

" viable DRSC11194 IE -0.805357948 -2.044235907 -4.00460864 -2.869504569 1.178547913 -0.286681012 FBgn0025441 Dhc1 Dynein heavy chain 1 http://flybase.org/reports/FBgn0025441 - gene motor activity ; GO:0003774 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "DHC, dhc, Dhc, DmDhc1, Dhc1, dynein" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066076 Stalker4\ORF2 Stalker4 element ORF2 http://flybase.org/reports/FBgn0066076 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "Stalker4\ORF2, ORF2" "IPR026523:Paraneoplastic antigen Ma, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain, IPR015416:Zinc finger, H2C2-type, histone UAS binding" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014999 tmo tammo http://flybase.org/reports/FBgn0014999 - gene - - - tmo - - 11-Aug-17 DroID_v2017_08 - - - - - - macrochaeta FBgn0003342 sct scooped thickvein http://flybase.org/reports/FBgn0003342 - gene - - - sct - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority live,male sterile,eye color defective" "wing,wing vein,eye,tergite" FBgn0261598 M(2)31E Minute (2) 31E http://flybase.org/reports/FBgn0261598 gene - - - M(2)31E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028028 l(3)S103114 lethal (3) S103114 http://flybase.org/reports/FBgn0028028 gene - - - "1031/14, l(3)S103114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266359 CR45007 - http://flybase.org/reports/FBgn0266359 non_protein_coding_gene - - - CR45007 - CR45007 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267809 CR46134 - http://flybase.org/reports/FBgn0267809 non_protein_coding_gene - - - CR46134 - CR46134 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266412 CR45052 - http://flybase.org/reports/FBgn0266412 non_protein_coding_gene - - - CR45052 - CR45052 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001877 l(1)YA13 lethal (1) YA13 http://flybase.org/reports/FBgn0001877 - gene - - - l(1)YA13 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267160 CR45600 - http://flybase.org/reports/FBgn0267160 non_protein_coding_gene - - - CR45600 - CR45600 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015453 l(1)HM32 lethal (1) HM32 http://flybase.org/reports/FBgn0015453 - gene - - - l(1)HM32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021968 l(2)k10012 lethal (2) k10012 http://flybase.org/reports/FBgn0021968 - gene - - - l(2)k10012 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046878 Obp83cd Odorant-binding protein 83cd http://flybase.org/reports/FBgn0046878 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "CG15582, Obp83c, Obp83d, 83c-2, 83c-1, 83d, 83c, Obp83cd, DmelObp83cd" IPR006170:Pheromone/general odorant binding protein CG15582 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259215 Ir93a Ionotropic receptor 93a http://flybase.org/reports/FBgn0259215 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir93a, IR93a, CT35907, CG17274, CG17275, DmelIR93a, CG42315, ir93a" IPR001320:Ionotropic glutamate receptor CG42315 11-Aug-17 DroID_v2017_08 "Drer\grin2aa, Drer\LOC100149482, Drer\grin2ab, Drer\grin2bb, Drer\grin2da, Drer\grin3ba, Drer\LOC100329743, Drer\grin3a, Drer\grin2cb, Drer\grin3bb" - "Cele\nmr-2, Cele\glr-1, Cele\glr-8, Cele\glr-2" - "Mmus\Grin2c, Mmus\Grin2b, Mmus\Grin2a, Mmus\Grin3b, Mmus\Grin3a, Mmus\Grin2d" "Hsap\GRIN2B, Hsap\GRIN3B, Hsap\GRIN2D, Hsap\GRIN3A, Hsap\GRIN2A, Hsap\GRIN2C" viable FBgn0083153 S(smoDN)189 Suppressor of smoDN 189 http://flybase.org/reports/FBgn0083153 gene - - - S(smoDN)189 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034075 Asph Aspartyl beta-hydroxylase http://flybase.org/reports/FBgn0034075 protein_coding_gene - peptidyl-amino acid modification ; GO:0018193 | inferred from electronic annotation with InterPro:IPR007803 endomembrane system ; GO:0012505 | inferred from direct assay "BAH/humbug, CG18658, CG8421, Asph" "IPR007803:Aspartyl/asparaginy/proline hydroxylase, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR027443:Isopenicillin N synthase-like" CG8421 11-Aug-17 DroID_v2017_08 "Drer\leo1, Drer\unm_hu7910, Drer\asphd2, Drer\asphd1, Drer\asph, Drer\rp1" Scer\YFR016C Cele\K09A9.6 Xtro\leo1 "Mmus\Dmp1, Mmus\Leo1, Mmus\Asph, Mmus\Asphd2, Mmus\Rp1, Mmus\Asphd1, Mmus\Ibsp" "Hsap\ASPH, Hsap\DMP1, Hsap\LEO1, Hsap\IBSP, Hsap\ASPHD1, Hsap\ASPHD2, Hsap\RP1" "viable,fertile" FBgn0085637 CG41374 - http://flybase.org/reports/FBgn0085637 protein_coding_gene - - - CG41374 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053629 CR33629 - http://flybase.org/reports/FBgn0053629 pseudogene_attribute - - - "CG33629, CR33629" - CR33629 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004660 l(2)41Ae lethal (2) 41Ae http://flybase.org/reports/FBgn0004660 "FBgn0002065, FBgn0002166, FBgn0002169, FBgn0020393" gene - - - "41Ae, l(2)EMS34-14, l(2R)34-2, GroupIV, l(2R)A', l(2)Sp9b, l(2)C147, l(2)C124, l(2)41Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267256 CR45692 - http://flybase.org/reports/FBgn0267256 non_protein_coding_gene - - - CR45692 - CR45692 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031163 CG14579 - http://flybase.org/reports/FBgn0031163 protein_coding_gene - - - CG14579 - CG14579 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035788 CG8541 - http://flybase.org/reports/FBgn0035788 protein_coding_gene - - - CG8541 IPR022727:Pupal cuticle protein C1 CG8541 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069305 X-75-9 X-75-9 http://flybase.org/reports/FBgn0069305 gene molecular_function ; GO:0003674 | no biological data available nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-75-9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,neurogenic phenotype,recessive,some die during embryonic stage" FBgn0259870 Su(Ste):CR42439 Su(Ste):CR42439 http://flybase.org/reports/FBgn0259870 non_protein_coding_gene - - - "Su(Ste):CR42439, CR42439" - CR42439 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261674 CG42709 - http://flybase.org/reports/FBgn0261674 protein_coding_gene - axonogenesis ; GO:0007409 | inferred from biological aspect of ancestor with PANTHER:PTN000689992 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 proteinaceous extracellular matrix ; GO:0005578 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 "CG17667, CG42709, EP3622, EP(3)3622" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype" CG42709 11-Aug-17 DroID_v2017_08 "Drer\lingo2b, Drer\ogmb, Drer\zmp:0000001073, Drer\zgc:153913, Drer\si:ch211-191d15.2, Drer\LOC100535105, Drer\lrrtm1, Drer\lrrc3, Drer\lrrc4c, Drer\lrit2, Drer\si:ch211-180f4.1, Drer\lrtm2b, Drer\LOC101883217, Drer\zgc:193598, Drer\lrrc38a, Drer\chad, Drer\lrfn2b, Drer\lrit3b, Drer\lrfn5a, Drer\si:ch211-106k21.5, Drer\lingo3a, Drer\ogn, Drer\lrfn5b, Drer\aspn, Drer\lrfn4a, Drer\si:dkey-90m5.4, Drer\nyx, Drer\lingo2a, Drer\zgc:172282, Drer\optc, Drer\epyc, Drer\lrfn1, Drer\lrit1b, Drer\lrfn2, Drer\lrrc3b, Drer\lrrn2, Drer\si:ch211-159i8.4, Drer\LOC100151059, Drer\lrrn1, Drer\lrrc38b, Drer\lrfn4b, Drer\lingo1b, Drer\lrtm2a, Drer\lingo1a" - Cele\lron-8 "Xtro\lgi4, Xtro\prelp, Xtro\lgi1, Xtro\lrtm2, Xtro\lum, Xtro\lrrc3b, Xtro\nyx, Xtro\lrrc3" "Mmus\Lrfn1, Mmus\Nyx, Mmus\Lingo1, Mmus\Tlr9, Mmus\Cpn2, Mmus\Lrfn2, Mmus\Lrrc17, Mmus\Lrrc52, Mmus\Gp5, Mmus\Lrrc3b, Mmus\Lrrc3, Mmus\Lrfn4, Mmus\Lrrc26, Mmus\Lrrn3, Mmus\Lrrc55, Mmus\Epyc, Mmus\Lrrc38, Mmus\Lrtm2, Mmus\Lrit2, Mmus\Ogn, Mmus\Lingo3, Mmus\Lrrn1, Mmus\Lrfn3, Mmus\Lingo2, Mmus\Slitrk3, Mmus\Omg, Mmus\Lrfn5, Mmus\Lrrn2" "Hsap\LRRC38, Hsap\LRRN2, Hsap\LRRC52, Hsap\LINGO2, Hsap\LRTM2, Hsap\CPN2, Hsap\LRRC55, Hsap\LRRC3B, Hsap\LRRC17, Hsap\LRRC3, Hsap\ASPN, Hsap\LRRN3, Hsap\LRRC70, Hsap\LRRC3C, Hsap\OMG, Hsap\LRRC26, Hsap\EPYC, Hsap\TLR9, Hsap\GP5, Hsap\OGN, Hsap\RTN4R, Hsap\LRFN2, Hsap\LRFN1, Hsap\LINGO1, Hsap\LINGO3, Hsap\LRRN1, Hsap\LRIT2, Hsap\LRFN3, Hsap\LRFN5, Hsap\LRFN4, Hsap\LRTM1" FBgn0001142 Gs1 Glutamine synthetase 1 http://flybase.org/reports/FBgn0001142 FBgn0003695 protein_coding_gene glutamate-ammonia ligase activity ; GO:0004356 | inferred from direct assay glutamine biosynthetic process ; GO:0006542 | inferred from electronic annotation with InterPro:IPR008147 phagocytosis ; GO:0006909 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype inferred from genetic interaction with SelD glutamine metabolic process ; GO:0006541 | inferred from mutant phenotype inferred from genetic interaction with SelD mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "GS1, mt-gs, fs(2)throng, fs(2)P52, GSI, gs-m, gsI, thg, l(2)21Bc, GsI, CG2718, Gs1" "IPR008146:Glutamine synthetase, catalytic domain, IPR008147:Glutamine synthetase, beta-Grasp domain, IPR014746:Glutamine synthetase/guanido kinase, catalytic domain, IPR027302:Glutamine synthetase, N-terminal conserved site, IPR027303:Glutamine synthetase, glycine-rich site" CG2718 11-Aug-17 DroID_v2017_08 "Drer\glulc, Drer\lgsn, Drer\glulb, Drer\glula" Scer\GLN1 "Cele\gln-6, Cele\gln-2, Cele\gln-5, Cele\gln-1, Cele\gln-3" "Xtro\lgsn, Xtro\glul" "Mmus\Lgsn, Mmus\Glul" "Hsap\LGSN, Hsap\GLUL" " pupal stage | late , larval stage | second instar , embryonic stage , larval stage | first instar " "chemical sensitive,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,female sterile,non-rescuable maternal effect,lethal,wild-type,electrophoretic variant,slow,fast,immune response defective,viable" "A1-7 dorsal oblique muscle 2,embryonic somatic muscle,muscle attachment site" FBgn0004374 neb nebbish http://flybase.org/reports/FBgn0004374 "FBgn0010543, FBgn0015262, FBgn0019965, FBgn0022079" protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity chromatin binding ; GO:0003682 | traceable author statement protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with Pp1-87B protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity with Khc ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | traceable author statement" "microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | traceable author statement microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with Khc mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from genetic interaction with nod mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype" heterochromatin ; GO:0000792 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "Klp38B, KLP38B, CG10718, Dm0332, 38B.12, 38B.10, DmKlp38B, l(2)k00802, tio, KLP 38B, Klp38, klp38B, KLP-38B, Mot, sl(2)ry3, sl(2)ry, l(2)k07614, l(2)03552, neb, Neb, nebb, KIF 14, DmNeb, KIF14" "IPR000253:Forkhead-associated (FHA) domain, IPR001752:Kinesin motor domain, IPR008984:SMAD/FHA domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10718 11-Aug-17 DroID_v2017_08 "Drer\stard9, Drer\kif1c, Drer\kif1aa, Drer\kif13ba, Drer\kif16ba, Drer\si:rp71-84d9.2, Drer\kif1ab, Drer\kif13bb, Drer\kif16bb, Drer\kif14" "Scer\CIN8, Scer\KIP1, Scer\SMY1" Cele\klp-6 "Xtro\kif14, Xtro\kif1a, Xtro\kif16b, Xtro\kif1c, Xtro\kif1b, Xtro\kif13b" "Mmus\Stard9, Mmus\Gm1305, Mmus\Kif16b, Mmus\Kif14, Mmus\Kif13a, Mmus\Kif1a, Mmus\Kif13b, Mmus\Kif1c, Mmus\Kif1b" "Hsap\KIF1A, Hsap\KIF14, Hsap\KIF1C, Hsap\STARD9, Hsap\KIF13A, Hsap\KIF13B, Hsap\KIF16B, Hsap\KIF1B" " adult stage && oogenesis stage , embryonic stage | mid , spermatogenesis && adult stage , embryonic stage && adult stage , adult stage , larval stage | third instar , larval stage , embryonic stage , embryonic stage | early " " ovary

, procephalic neuroblast

, testis

, spermatocyte

, primary gonial cell

, imaginal disc

, larval brain | restricted

, imaginal disc | restricted

, nurse cell

, ventral nerve cord

, follicle cell

" "mitotic cell cycle defective,lethal,recessive,female sterile,male sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during immature adult stage,behavior defective,partially lethal - majority die,some die during larval stage,viable,maternal effect,partially,rescuable maternal effect,wild-type,germline clone" "nuclear chromosome,centrosome,eye,macrochaeta,external sensory organ,multidendritic neuron,chordotonal organ,lateral,neuron,interommatidial bristle,wing,egg,maternal effect,embryo,syncytial blastoderm embryo,pole cell,nucleus | blastoderm stage | maternal effect,spindle | embryonic stage | maternal effect,chromatin | embryonic stage | maternal effect,ommatidium,adult abdominal sensillum,spermatozoon,egg chamber,ovary,follicle cell,adult neuroblast & mitosis & nuclear chromosome,adult neuroblast & spindle,humeral bristle,adult abdomen,embryonic/larval brain,embryonic epidermis,germline clone,embryonic/first instar larval cuticle,embryonic abdominal segment,embryonic head,embryonic abdomen" FBgn0259630 B2034 - http://flybase.org/reports/FBgn0259630 gene - - - B2034 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,unguis,wing,eye" FBgn0066096 MSu1 MSu1 http://flybase.org/reports/FBgn0066096 gene - - - MSu1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005617 msl-1 male-specific lethal 1 http://flybase.org/reports/FBgn0005617 "FBgn0001318, FBgn0002851" protein_coding_gene DNA binding ; GO:0003677 | non-traceable author statement DNA binding ; GO:0003677 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with tamo ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with msl-2 transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay protein dimerization activity ; GO:0046983 | inferred from physical interaction with msl-1 histone H4-K16 acetylation ; GO:0043984 | inferred from electronic annotation with InterPro:IPR026711 dosage compensation by hyperactivation of X chromosome ; GO:0009047 | non-traceable author statement dosage compensation ; GO:0007549 | inferred from mutant phenotype negative regulation of chromatin silencing ; GO:0031936 | inferred from mutant phenotype dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome ; GO:0016457 | traceable author statement "MSL complex ; GO:0072487 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | non-traceable author statement X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | traceable author statement dosage compensation complex ; GO:0046536 | inferred from direct assay X chromosome ; GO:0000805 | non-traceable author statement chromosome ; GO:0005694 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay" "MSL1, msl1, msl-1, MSL-1, msl, Msl1, MSL, i94, CG10385, mls-1, km(2)B, kmB, Msl 1-3, Msl-1" "IPR029332:PEHE domain, IPR026711:Protein male-specific lethal-1" CG10385 11-Aug-17 DroID_v2017_08 "Drer\msl1b, Drer\msl1a" - - Xtro\msl1 Mmus\Msl1 Hsap\MSL1 " embryonic stage -- adult stage , adult stage | female , adult stage | male " " adult stage | male , larval stage | male , larval stage | female , embryonic stage " "viable,fertile,lethal,male limited,heat sensitive,male,female,recessive,wild-type,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,partially,short lived,visible" "trichogen cell,mesothoracic tergum" FBgn0261866 ltr loiterer http://flybase.org/reports/FBgn0261866 gene - larval foraging behavior ; GO:0035177 | inferred from mutant phenotype - ltr - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0065341 l(2)SH1834 lethal (2) SH1834 http://flybase.net/reports/FBgn0065341.html gene l(2)SH2 1834 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0014990 l(2)46Df lethal (2) 46Df http://flybase.org/reports/FBgn0014990 - gene - - - "XII, l(2)46Df" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265416 Neto Neuropilin and tolloid-like http://flybase.org/reports/FBgn0265416 protein_coding_gene molecular_function ; GO:0003674 | no biological data available glutamate receptor clustering ; GO:0097688 | inferred from mutant phenotype postsynaptic density organization ; GO:0097106 | inferred from mutant phenotype hatching behavior ; GO:0035187 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of BMP signaling pathway ; GO:0030510 | inferred from genetic interaction with put inferred from genetic interaction with Mad inferred from genetic interaction with wit inferred from genetic interaction with gbb neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype receptor clustering ; GO:0043113 | inferred from mutant phenotype postsynaptic membrane organization ; GO:0001941 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype ionotropic glutamate receptor complex ; GO:0008328 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay "net, CG44328, CG32635, tld-like, CT36003, CG15752, CG15751, CG12727, Neto, neto, CG15753, NETO" "IPR000859:CUB domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR011990:Tetratricopeptide-like helical domain" CG44328 11-Aug-17 DroID_v2017_08 "Drer\neto1, Drer\si:ch211-233f16.1, Drer\neto1l, Drer\neto2b" - Cele\neto-1 "Xtro\neto2, Xtro\neto1" "Mmus\Neto1, Mmus\Neto2" "Hsap\NETO1, Hsap\NETO2" DRSC19503 K 0.150061825 0.125724018 0.910320035 0.018075519 -1.657726525 -0.803162426 FBgn0029906 xit xiantuan http://flybase.org/reports/FBgn0029906 protein_coding_gene "dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity ; GO:0042283 | inferred from sequence or structural similarity with SGD:S000005593 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity ; GO:0042281 | inferred from biological aspect of ancestor with PANTHER:PTN000275691" germ-band extension ; GO:0007377 | inferred from mutant phenotype oligosaccharide-lipid intermediate biosynthetic process ; GO:0006490 | inferred from sequence or structural similarity with SGD:S000005593 oligosaccharide-lipid intermediate biosynthetic process ; GO:0006490 | inferred from biological aspect of ancestor with PANTHER:PTN000275691 protein N-linked glycosylation ; GO:0006487 | inferred from sequence or structural similarity with SGD:S000005593 protein N-linked glycosylation ; GO:0006487 | inferred from biological aspect of ancestor with PANTHER:PTN000275691 protein glycosylation ; GO:0006486 | inferred from mutant phenotype apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000275691 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with SGD:S000005593 "xit, CG4542, Dalg8, dAlg8" "IPR004856:Glycosyl transferase, ALG6/ALG8" CG4542 11-Aug-17 DroID_v2017_08 "Drer\mmp24, Drer\mmp23ba, Drer\mmp15a, Drer\alg8, Drer\mmp20a, Drer\mmp14a, Drer\mmp23bb, Drer\mmp2, Drer\mmp15b, Drer\mmp14b, Drer\mmp28, Drer\mmp20b, Drer\mmp17b, Drer\mmp25b, Drer\mmp11a, Drer\mmp17a, Drer\mmp11b, Drer\mmp30, Drer\mmp25a, Drer\mmp19, Drer\mmp13b, Drer\mmp16b" "Scer\ALG6, Scer\ALG8" "Cele\C08B11.8, Cele\zmp-3, Cele\zmp-6, Cele\zmp-2, Cele\zmp-5, Cele\W01F3.2, Cele\C08H9.3" "Xtro\mmp2, Xtro\mmp13, Xtro\mmp19, Xtro\mmp15, Xtro\alg8, Xtro\mmp25, Xtro\mmp1, Xtro\mmp8, Xtro\LOC100490019, Xtro\mmp14, Xtro\mmp24, Xtro\mmp16, Xtro\mmp28, Xtro\mmp17, Xtro\mmp11, Xtro\mmp3" "Mmus\Alg8, Mmus\Mmp15, Mmus\Mmp16, Mmus\Mmp27, Mmus\Mmp3, Mmus\Mmp7, Mmus\Mmp1a, Mmus\Mmp14, Mmus\Mmp13, Mmus\Mmp11, Mmus\Mmp17, Mmus\Mmp8, Mmus\Mmp12, Mmus\Mmp2, Mmus\Mmp20, Mmus\Mmp23, Mmus\Mmp28, Mmus\Mmp25, Mmus\Mmp19, Mmus\Mmp10, Mmus\Mmp24" "Hsap\MMP20, Hsap\MMP15, Hsap\MMP24, Hsap\MMP7, Hsap\MMP19, Hsap\MMP17, Hsap\MMP26, Hsap\MMP2, Hsap\MMP13, Hsap\MMP14, Hsap\MMP11, Hsap\MMP27, Hsap\ALG8, Hsap\MMP1, Hsap\MMP25, Hsap\MMP3, Hsap\MMP28, Hsap\MMP12, Hsap\MMP10, Hsap\MMP16, Hsap\MMP8" viable "cephalic furrow,germline clone,ventral furrow" FBgn0052113 CG32113 - http://flybase.org/reports/FBgn0052113 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay "CG11003, CG11002, CG32113" "IPR000772:Ricin B, lectin domain, IPR009543:Vacuolar protein sorting-associated protein 13, SHR-binding domain, IPR026847:Vacuolar protein sorting-associated protein 13, IPR026854:Vacuolar protein sorting-associated protein 13, N-terminal domain, IPR031642:VPS13, repeated coiled region, IPR031646:Vacuolar protein sorting-associated protein 13, second N-terminal domain, IPR031645:Vacuolar protein sorting-associated protein 13, C-terminal" CG32113 11-Aug-17 DroID_v2017_08 "Drer\vps13a, Drer\LOC101882151, Drer\vps13d" Scer\VPS13 "Cele\T08G11.1, Cele\C25H3.11, Cele\C25H3.8" Xtro\vps13d "Mmus\Vps13b, Mmus\Vps13d, Mmus\Vps13c, Mmus\Vps13a" "Hsap\VPS13C, Hsap\VPS13A, Hsap\VPS13B, Hsap\VPS13D" "viable,visible" trichogen cell FBgn0267075 CR45519 - http://flybase.org/reports/FBgn0267075 non_protein_coding_gene - - - CR45519 - CR45519 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043043 Desat2 Desaturase 2 http://flybase.org/reports/FBgn0043043 protein_coding_gene "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water ; GO:0016717 | inferred from electronic annotation with InterPro:IPR015876" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015876 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804 - "desat2/Fad, ds2, CG5925, 7-11HD, desat, Fad, Desat2, desat2, desat-2" "IPR005804:Fatty acid desaturase domain, IPR015876:Acyl-CoA desaturase" CG5925 11-Aug-17 DroID_v2017_08 "Drer\scdb, Drer\scd" Scer\OLE1 "Cele\fat-7, Cele\fat-6, Cele\fat-5" Xtro\scd "Mmus\Scd4, Mmus\Scd3, Mmus\Scd2, Mmus\Scd1" "Hsap\SCD5, Hsap\SCD" FBgn0034390 CG15093 - http://flybase.org/reports/FBgn0034390 protein_coding_gene "phosphogluconate dehydrogenase (decarboxylating) activity ; GO:0004616 | inferred from electronic annotation with InterPro:IPR006115 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR011548, InterPro:IPR029154 3-hydroxyisobutyrate dehydrogenase activity ; GO:0008442 | inferred from sequence or structural similarity with UniProtKB:P31937" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002204, InterPro:IPR006115, InterPro:IPR008927, InterPro:IPR011548, InterPro:IPR013328, InterPro:IPR015815 cellular amino acid metabolic process ; GO:0006520 | inferred from sequence or structural similarity with UniProtKB:P31937" lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P31937 "CT34968, CG15093, CG 15093" "IPR002204:3-hydroxyisobutyrate dehydrogenase-related, conserved site, IPR006115:6-phosphogluconate dehydrogenase, NADP-binding, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR011548:3-hydroxyisobutyrate dehydrogenase, IPR015815:3-hydroxyisobutyrate dehydrogenase-related, IPR013328:6-phosphogluconate dehydrogenase, domain 2, IPR016040:NAD(P)-binding domain, IPR029154:3-hydroxyisobutyrate dehydrogenase, NAD-binding domain" CG15093 11-Aug-17 DroID_v2017_08 "Drer\glyr1, Drer\hibadhb, Drer\rogdi, Drer\hibadha" - Cele\B0250.5 "Xtro\hibadh, Xtro\glyr1" "Mmus\Glyr1, Mmus\Hibadh" "Hsap\HIBADH, Hsap\GLYR1" "viable,fertile" FBgn0053673 CG33673 - http://flybase.org/reports/FBgn0053673 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33673 IPR006214:Bax inhibitor 1-related CG33673 11-Aug-17 DroID_v2017_08 "Drer\faim2b, Drer\grinaa, Drer\LOC566927, Drer\faim2a, Drer\grinab, Drer\zgc:110410, Drer\si:ch211-284o19.8, Drer\tmbim4, Drer\tmbim1" Scer\BXI1 "Cele\Y42H9AR.2, Cele\tag-120, Cele\xbx-6" "Xtro\faim2, Xtro\tmbim1, Xtro\tmbim4" "Mmus\Grina, Mmus\Tmbim1, Mmus\Tmbim4, Mmus\Faim2, Mmus\Tmbim7" "Hsap\FAIM2, Hsap\GRINA, Hsap\TMBIM1, Hsap\TMBIM4" FBgn0263472 snoRNA:2R:9445205 - http://flybase.org/reports/FBgn0263472 snoRNA_gene - - - "snoRNA:2R:9445205, snoRNA:2R_9445205, chr2R:9073472..9073780" - CR43587 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002965 npr3 non-pupariating 3 http://flybase.org/reports/FBgn0002965 FBgn0001608 gene - - - "l(1)d deg-12, l(1)d.deg.12, l(1)npr-3, l(1)dd12, l(1)d.deg.-12, npr3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,cell cycle" FBgn0259440 EP-435 - http://flybase.org/reports/FBgn0259440 gene - - - EP-435 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0010040 GstD4 Glutathione S transferase D4 http://flybase.org/reports/FBgn0010040 FBgn0038023 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTD4, DmGST23, Gst, GST, gstD23, GstD23, CG11512, GstD4, GSTD4, DmGstd4, gstd4" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG11512 11-Aug-17 DroID_v2017_08 "Drer\eef1g, Drer\gstt1a, Drer\vars, Drer\gstr, Drer\mars, Drer\gstt2, Drer\eef1e1, Drer\gstt1b" "Scer\TEF4, Scer\GTT2, Scer\URE2, Scer\CAM1, Scer\YGR201C, Scer\GTT1" - "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Mars, Mmus\Eef1g, Mmus\Gstt1, Mmus\Gstt4, Mmus\Gstt3, Mmus\Eef1e1, Mmus\Gstt2, Mmus\Vars" "Hsap\VARS, Hsap\EEF1G, Hsap\EEF1E1, Hsap\MARS, Hsap\GSTT2B, Hsap\GSTT1, Hsap\GSTT2" adult stage viable FBgn0259370 EP-1152.2 - http://flybase.org/reports/FBgn0259370 gene - - - EP-1152.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0013348 TpnC41C Troponin C at 41C http://flybase.org/reports/FBgn0013348 "FBan0041446, FBgn0084010" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "TnC, CG2981, DmTpnCIIIa, DmTpnC41C, TpnC IIIa, DmTnC1, TPNC, TnC41C, TpnC41C, TnC1, TpnCIIIa, TNC41C, TpnC41, Tnc1" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG2981 11-Aug-17 DroID_v2017_08 "Drer\caln1, Drer\calml4a, Drer\calm3a, Drer\cabp2a, Drer\calb1, Drer\calb2b, Drer\scgn, Drer\efcab11, Drer\calm1a, Drer\pvalb4, Drer\pvalb6, Drer\calb2a, Drer\cabp1b, Drer\pvalb1, Drer\cabp7b, Drer\pvalb2, Drer\calm3b, Drer\rhbdl3, Drer\si:ch211-197n1.2, Drer\efcab6, Drer\calml4b, Drer\calm2a, Drer\pvalb8, Drer\cabp5a, Drer\tnnc2, Drer\caln2, Drer\cabp4, Drer\calm2b, Drer\cabp5b, Drer\pvalb3, Drer\calm1b, Drer\pvalb9, Drer\efcab2, Drer\tnnc1a, Drer\tnnc1b, Drer\cabp1a, Drer\cabp2b" "Scer\MLC1, Scer\CMD1, Scer\CDC31, Scer\MLC2" "Cele\pat-10, Cele\cmd-1, Cele\cal-4, Cele\cal-2, Cele\cal-1, Cele\cal-3, Cele\tnc-2" "Xtro\calm2, Xtro\cabp7, Xtro\pgm1, Xtro\calm1, Xtro\pvalb.1, Xtro\cabp4, Xtro\calb1, Xtro\tnnc1, Xtro\scgn, Xtro\calml4, Xtro\tnnc2, Xtro\pvalb, Xtro\ocm.2, Xtro\ocm, Xtro\efcab6, Xtro\pvalb.2, Xtro\LOC548651" "Mmus\Calb2, Mmus\Caln1, Mmus\Cabp1, Mmus\1700023F06Rik, Mmus\Tnnc1, Mmus\Efcab3, Mmus\Ocm, Mmus\Cabp5, Mmus\Pvalb, Mmus\Calm2, Mmus\Cabp2, Mmus\Calm5, Mmus\Calm3, Mmus\Spata21, Mmus\Calb1, Mmus\Efcab11, Mmus\Efcab9, Mmus\Efcab7, Mmus\Calml4, Mmus\Efcab6, Mmus\Calm1, Mmus\Cabp7, Mmus\Scgn, Mmus\Rhbdl3, Mmus\Efcab2, Mmus\Calm4, Mmus\Calml3, Mmus\Tnnc2, Mmus\Cabp4" "Hsap\CALML5, Hsap\TNNC2, Hsap\CALB1, Hsap\EFCAB2, Hsap\EFCAB7, Hsap\TNNC1, Hsap\CABP5, Hsap\RHBDL3, Hsap\CALML6, Hsap\CALM3, Hsap\CABP1, Hsap\CALB2, Hsap\EFCAB9, Hsap\OCM, Hsap\CALML3, Hsap\CABP2, Hsap\EFCAB13, Hsap\CALM2, Hsap\EFCAB11, Hsap\SCGN, Hsap\PVALB, Hsap\EFCAB6, Hsap\CALM1, Hsap\OCM2, Hsap\EFCAB3, Hsap\CALML4, Hsap\CABP7, Hsap\CABP4, Hsap\CALN1, Hsap\SPATA21" " pupal stage | mid , adult stage , pupal stage--adult stage , pupal stage | late " organism

adult stage " leg

, indirect flight muscle

" FBgn0264528 ff25 - http://flybase.org/reports/FBgn0264528 gene - - - ff25 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" FBgn0065975 iab4-5.s iab4-5.s http://flybase.org/reports/FBgn0065975 gene - - - "4-5 s, iab4-5.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034496 CG9143 - http://flybase.org/reports/FBgn0034496 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000000346 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "cg9143, CG9143" "IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9143 11-Aug-17 DroID_v2017_08 Drer\ddx24 Scer\MAK5 Cele\F55F8.2 Xtro\ddx24 Mmus\Ddx24 Hsap\DDX24 "viable,fertile" FBgn0065168 l(3)SH031 lethal (3) SH031 http://flybase.org/reports/FBgn0065168 gene - - - "l(3)SH031, l(2)SH3 031" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016003 l(3)61Da lethal (3) 61Da http://flybase.org/reports/FBgn0016003 - gene - - - l(3)61Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031493 Sf3b2 Splicing factor 3b subunit 2 http://flybase.org/reports/FBgn0031493 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:10769 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004853 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN001765154" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2-type spliceosomal complex ; GO:0005684 | inferred from biological aspect of ancestor with PANTHER:PTN001765154 U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000004853 U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN001765154 U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN001765154 "CG3605, Sf3b2, SF3B2" "IPR006568:PSP, proline-rich, IPR007180:Domain of unknown function DUF382" CG3605 11-Aug-17 DroID_v2017_08 Drer\sf3b2 Scer\CUS1 Cele\W03F9.10 Xtro\sf3b2 Mmus\Sf3b2 Hsap\SF3B2 lethal DRSC00619 EK -0.44974458 1.428024303 -2.493881031 -1.830599245 -1.666780762 -1.307860185 FBgn0034821 CG9876 - http://flybase.org/reports/FBgn0034821 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - CG9876 "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site" CG9876 11-Aug-17 DroID_v2017_08 "Drer\prrx1b, Drer\isl2b, Drer\si:dkey-43p13.5, Drer\alx4a, Drer\alx3, Drer\uncx, Drer\uncx4.1, Drer\alx1, Drer\prrx1a" - "Cele\unc-42, Cele\dsc-1, Cele\alr-1, Cele\unc-4" "Xtro\prrx1, Xtro\alx1, Xtro\prrx2, Xtro\alx4, Xtro\uncx" "Mmus\Lmx1b, Mmus\Prrx1, Mmus\Prrx2, Mmus\Alx3, Mmus\Uncx, Mmus\Alx1, Mmus\Alx4" "Hsap\ALX3, Hsap\ALX1, Hsap\UNCX, Hsap\ALX4, Hsap\PRRX2, Hsap\PRRX1" "viable,fertile" DRSC04586 I 1.769620343 0.214193936 1.027371655 -0.075117282 -0.30382595 -1.063932979 FBgn0265543 CR44393 - http://flybase.org/reports/FBgn0265543 non_protein_coding_gene - - - "CR44393, lincRNA.164" - CR44393 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013537 l(2)ry41 lethal (2) ry41 http://flybase.org/reports/FBgn0013537 - gene - - - "l(2)41, l(2)ry41" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0030700 CG15914 - http://flybase.org/reports/FBgn0030700 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "PIG, CG15914" "IPR001296:Glycosyl transferase, family 1, IPR022701:Glycosyltransferase family 1, N-terminal" CG15914 11-Aug-17 DroID_v2017_08 Drer\gtdc1 - - Xtro\gtdc1 Mmus\Gtdc1 Hsap\GTDC1 viable FBgn0259552 GG01228 - http://flybase.org/reports/FBgn0259552 gene - - - GG01228 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0040011 Slmap Sarcolemma associated protein http://flybase.org/reports/FBgn0040011 protein_coding_gene - positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D - "CG17494, Slmap" "IPR000253:Forkhead-associated (FHA) domain, IPR008984:SMAD/FHA domain" CG17494 11-Aug-17 DroID_v2017_08 "Drer\LOC100330186, Drer\slmapa, Drer\ccdc136b, Drer\slmapb" "Scer\VPS64, Scer\DMA2, Scer\FAR10, Scer\DMA1" Cele\M4.1 "Xtro\ccdc136, Xtro\slmap" "Mmus\Slmap, Mmus\Traf3ip3, Mmus\Ccdc136" "Hsap\CCDC136, Hsap\TRAF3IP3, Hsap\SLMAP" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0066088 RH13 RNA Helicase 13 http://flybase.org/reports/FBgn0066088 gene - - - "DmRH13, RH13" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085555 CG41018 - http://flybase.org/reports/FBgn0085555 protein_coding_gene - - - CG41018 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259471 EP-241 - http://flybase.org/reports/FBgn0259471 gene - - - EP-241 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0263850 CG43711 - http://flybase.org/reports/FBgn0263850 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43711 - CG43711 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039867 CstF50 Cleavage stimulation factor 50 kD subunit http://flybase.org/reports/FBgn0039867 protein_coding_gene - - nucleoplasm ; GO:0005654 | inferred from direct assay mRNA cleavage stimulating factor complex ; GO:0005848 | inferred from direct assay "CstF50, CG2261, CstF-50" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like, IPR032028:Cleavage stimulation factor subunit 1, dimerisation domain, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG2261 11-Aug-17 DroID_v2017_08 Drer\cstf1 Scer\TAF5 Cele\cpf-1 Xtro\cstf1 Mmus\Cstf1 Hsap\CSTF1 viable DRSC15434 I 2.516826499 2.220094545 0.882436123 0.258475278 -0.027015959 -0.090801024 FBgn0004115 Su(var)311 Suppressor of variegation 311 http://flybase.org/reports/FBgn0004115 - gene - - - Su(var)311 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265950 CR44737 - http://flybase.org/reports/FBgn0265950 non_protein_coding_gene - - - "CR44737, lincRNA.188, lincRNA.189" - CR44737 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267488 Mcr Macroglobulin complement-related http://flybase.org/reports/FBgn0267488 protein_coding_gene "endopeptidase inhibitor activity ; GO:0004866 | inferred from electronic annotation with InterPro:IPR001599, InterPro:IPR002890 protein binding ; GO:0005515 | inferred from physical interaction with egg structural molecule activity ; GO:0005198 | inferred from mutant phenotype" "lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype phagocytosis, recognition ; GO:0006910 | inferred from mutant phenotype" septate junction ; GO:0005918 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model apicolateral plasma membrane ; GO:0016327 | inferred from direct assay "Mcr, luf, CG7586, TEP6mel, Tep6, DmTEP6, TepVI, dTEPVI, mcr, alpha-2-Mrp, anon-28DE, TEP6, E(br)155" "IPR001599:Alpha-2-macroglobulin, IPR011626:Alpha-macroglobulin complement component, IPR011625:Alpha-2-macroglobulin, N-terminal 2, IPR009048:Alpha-macroglobulin, receptor-binding, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR002890:Alpha-2-macroglobulin, N-terminal, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR013783:Immunoglobulin-like fold" CG7586 11-Aug-17 DroID_v2017_08 "Drer\zgc:171445, Drer\zgc:165453, Drer\c3a.1, Drer\si:dkey-46g23.5, Drer\si:dkey-8k3.2, Drer\LOC103909927, Drer\zgc:165518, Drer\si:dkey-52d15.2, Drer\cd109, Drer\si:dkey-105h12.2, Drer\c5, Drer\a2ml, Drer\c3a.6, Drer\zgc:171446, Drer\si:ch211-212c13.10, Drer\zgc:171426, Drer\c3b.2, Drer\c3a.3, Drer\c3a.4, Drer\c3a.2, Drer\sb:cb37, Drer\c4, Drer\c3b.1, Drer\cpamd8, Drer\si:dkey-46g23.2" - Cele\tep-1 "Xtro\a2ml1, Xtro\c4a, Xtro\c5, Xtro\ovos2, Xtro\a2m, Xtro\pzp, Xtro\c3" "Mmus\Mug2, Mmus\AI182371, Mmus\Hc, Mmus\Pzp, Mmus\C3, Mmus\Mug1, Mmus\A2m, Mmus\BC048546, Mmus\C4b, Mmus\Cd109" "Hsap\C4B_2, Hsap\C5, Hsap\OVOS2, Hsap\CPAMD8, Hsap\A2M, Hsap\PZP, Hsap\A2ML1, Hsap\C4A, Hsap\C4B, Hsap\C3" " spermatogenesis && adult stage , embryonic stage " " spermatocyte

, testis

, embryonic peripheral nervous system

" FBgn0259938 cwo clockwork orange http://flybase.org/reports/FBgn0259938 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003650 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with Hey negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay circadian regulation of gene expression ; GO:0032922 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "cwo, CG17100, AAF24476.1, GM05287, bHLHe49, mel_cwo, CWO, Cwo, dcwo" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG17100 11-Aug-17 DroID_v2017_08 "Drer\her9, Drer\her7, Drer\her2, Drer\her8a, Drer\her4.4, Drer\her12, Drer\her4.3, Drer\her3, Drer\LOC100149863, Drer\hey1, Drer\her4.2, Drer\her15.2, Drer\hes6, Drer\hes2.2, Drer\her11, Drer\helt, Drer\bhlhe40, Drer\her6, Drer\her5, Drer\her8.2, Drer\heyl, Drer\hey2, Drer\her15.1, Drer\hes2.1, Drer\bhlhe41, Drer\her13, Drer\her1" Scer\PHO4 "Cele\lin-22, Cele\hlh-25, Cele\hlh-27" "Xtro\hes7.2, Xtro\hey2, Xtro\bhlhe40, Xtro\hey1, Xtro\hes6.1, Xtro\bhlhe41, Xtro\hes7.1, Xtro\hes4, Xtro\hes2, Xtro\hes1" "Mmus\Hes6, Mmus\Hes2, Mmus\Helt, Mmus\Hes1, Mmus\Heyl, Mmus\Bhlhe40, Mmus\Hey2, Mmus\Hes7, Mmus\Hey1, Mmus\Hes3, Mmus\Hes5, Mmus\Bhlhe41" "Hsap\HEY1, Hsap\HELT, Hsap\HES2, Hsap\HES3, Hsap\BHLHE41, Hsap\HES4, Hsap\HES1, Hsap\BHLHE40, Hsap\HES6, Hsap\HES5, Hsap\HEYL, Hsap\HEY2, Hsap\HES7" DRSC17072 E 1.004402566 -0.720398823 0.656748718 -2.280856114 0.498138928 -0.226399457 FBgn0011894 tRNA:Lys-CTT-1-8 transfer RNA:Lysine-CTT 1-8 http://flybase.org/reports/FBgn0011894 "FBgn0003796, FBgn0011886, FBgn0050302, FBgn0060182" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "tRNA[Lys][[2]], AE002778.trna2-LysCTT, tRNA:K2, tRNA:K:CTT:AE002778-b, CR30302, tRNA:lys2:42Ec, tRNAlys, chr2R.trna89-LysCTT, tRNA-Lys-CTT-1-8, tRNA:Lys-CTT-1-8, tRNA:K2:42Ec, AAG" - CR30302 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037888 scpr-B SCP-containing protein B http://flybase.org/reports/FBgn0037888 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "SCPR-B, CG17210, anon-WO0140519.115, scpr-B, scp-B, cg17210" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG17210 11-Aug-17 DroID_v2017_08 "Drer\pi15a, Drer\glipr1b, Drer\crispld2, Drer\r3hdml, Drer\LOC100536500, Drer\glipr2l, Drer\crispld1b, Drer\glipr2, Drer\pi15b, Drer\crispld1a" "Scer\PRY1, Scer\PRY2, Scer\PRY3" "Cele\scl-10, Cele\scl-1, Cele\vap-2, Cele\scl-23, Cele\scl-6, Cele\scl-20" "Xtro\crisp3, Xtro\crispld2, Xtro\crisp2, Xtro\r3hdml, Xtro\MGC108118, Xtro\glipr2, Xtro\crisp1" "Mmus\Crisp2, Mmus\Clec18a, Mmus\Crisp4, Mmus\Crisp1, Mmus\Glipr1l2, Mmus\Pi16, Mmus\Crispld2, Mmus\Crisp3, Mmus\Glipr1l1, Mmus\Pi15, Mmus\R3hdml, Mmus\Glipr2, Mmus\Crispld1, Mmus\Glipr1" "Hsap\PI16, Hsap\CRISP1, Hsap\R3HDML, Hsap\GLIPR1L2, Hsap\GLIPR1, Hsap\CLEC18B, Hsap\CRISP2, Hsap\CLEC18A, Hsap\GLIPR1L1, Hsap\CRISPLD2, Hsap\GLIPR2, Hsap\CRISPLD1, Hsap\PI15, Hsap\CLEC18C" "viable,fertile" FBgn0014241 l(2)32Ab lethal (2) 32Ab http://flybase.org/reports/FBgn0014241 - gene - - - l(2)32Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034612 CG10505 - http://flybase.org/reports/FBgn0034612 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" response to zinc ion ; GO:0010043 | inferred from genetic interaction with MTF-1 response to copper ion ; GO:0046688 | inferred from genetic interaction with MTF-1 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "Dme_CG10505, CG10505" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG10505 11-Aug-17 DroID_v2017_08 "Drer\abcc8, Drer\abcc12, Drer\abcc13, Drer\LOC100329706, Drer\abcc4, Drer\abcc3, Drer\cftr, Drer\abcc6b.2, Drer\abcc2, Drer\abcc5, Drer\abcc10, Drer\abcc9, Drer\abcc1, Drer\abcc6a" "Scer\BPT1, Scer\YBT1, Scer\VMR1, Scer\NFT1, Scer\STE6, Scer\YCF1, Scer\YKR104W, Scer\YOR1" "Cele\mrp-1, Cele\mrp-7, Cele\mrp-5, Cele\mrp-2, Cele\mrp-8, Cele\mrp-3, Cele\mrp-6, Cele\mrp-4" "Xtro\abcc3, Xtro\abcc4, Xtro\abcc1, Xtro\cftr, Xtro\abcc10, Xtro\abcc6" "Mmus\Abcc1, Mmus\Abcc8, Mmus\Abcc4, Mmus\Abcc9, Mmus\Abcc6, Mmus\Cftr, Mmus\Abcc5, Mmus\Abcc10, Mmus\Abcc3, Mmus\Abcc12, Mmus\Abcc2" "Hsap\ABCC11, Hsap\ABCC3, Hsap\ABCC1, Hsap\ABCC9, Hsap\CFTR, Hsap\ABCC2, Hsap\ABCC12, Hsap\ABCC6, Hsap\ABCC4, Hsap\ABCC10, Hsap\ABCC5, Hsap\ABCC8" viable FBgn0052704 Ir8a Ionotropic receptor 8a http://flybase.org/reports/FBgn0052704 protein_coding_gene "ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR019594 extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 olfactory receptor activity ; GO:0004984 | contributes_to inferred from direct assay extracellular phenylacetaldehyde-gated ion channel activity ; GO:0036082 | contributes_to inferred from direct assay ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model extracellular ligand-gated ion channel activity ; GO:0005230 | contributes_to inferred from direct assay receptor binding ; GO:0005102 | inferred from physical interaction with Ir84a coreceptor activity ; GO:0015026 | inferred from direct assay" ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 response to acetate ; GO:0010034 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern positive regulation of calcium-mediated signaling ; GO:0050850 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype response to chlorate ; GO:0010157 | inferred from mutant phenotype transmission of nerve impulse ; GO:0019226 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype cellular response to acetate ; GO:0071311 | inferred from direct assay receptor complex ; GO:0043235 | inferred from direct assay sensory dendrite ; GO:0071683 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from direct assay "Ir8a, CT7438, CG12666, CG12122, IR8a, CG32704, DmelIR8a" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG32704 11-Aug-17 DroID_v2017_08 "Drer\grin2da, Drer\grin2bb, Drer\LOC100149482, Drer\grid1a, Drer\grin3bb, Drer\grin2cb, Drer\grin2ab, Drer\LOC100329743, Drer\grin3ba, Drer\grin3a, Drer\grid2, Drer\grin2aa, Drer\grid1b" - "Cele\glr-2, Cele\glr-1, Cele\nmr-2" "Xtro\grid2, Xtro\grid1" "Mmus\Grin2a, Mmus\Grid1, Mmus\Grin3a, Mmus\Grid2, Mmus\Grin2c, Mmus\Grin2b, Mmus\Grin2d, Mmus\Grin3b" "Hsap\GRIN3B, Hsap\GRIN3A, Hsap\GRIN2C, Hsap\GRIN2B, Hsap\GRIN2A, Hsap\GRID2, Hsap\GRIN2D, Hsap\GRID1" "smell perception defective,viable,fertile,neurophysiology defective" sensillum coeloconicum of antennal segment 3 FBgn0065442 l(2)SH1454 lethal (2) SH1454 http://flybase.org/reports/FBgn0065442 gene - - - "l(2)SH1454, l(2)SH2 1454" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033507 CG12909 - http://flybase.org/reports/FBgn0033507 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG12909 "IPR014898:Zinc finger, C2H2, LYAR-type, IPR013087:Zinc finger C2H2-type" CG12909 11-Aug-17 DroID_v2017_08 Drer\lyar Scer\YCR087C-A Cele\C16C10.8 Xtro\lyar Mmus\Lyar Hsap\LYAR viable FBgn0043988 Su(rst)E156 Su(rst)E156 http://flybase.org/reports/FBgn0043988 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E156, Su(rst)E156" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052483 CG32483 - http://flybase.org/reports/FBgn0052483 protein_coding_gene serine-type carboxypeptidase activity ; GO:0004185 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 - CG32483 "IPR001563:Peptidase S10, serine carboxypeptidase, IPR029058:Alpha/Beta hydrolase fold" CG32483 11-Aug-17 DroID_v2017_08 "Drer\scpep1, Drer\cpvl, Drer\si:ch211-122f10.4" "Scer\KEX1, Scer\PRC1, Scer\YBR139W" "Cele\ctsa-1, Cele\F41C3.5, Cele\F13D12.6, Cele\F22E12.1, Cele\ctsa-2, Cele\Y32F6A.5" "Xtro\cpvl, Xtro\ctsa, Xtro\scpep1" "Mmus\Cpvl, Mmus\Ctsa, Mmus\Scpep1" "Hsap\SCPEP1, Hsap\CTSA" viable FBgn0002099 l(2)57Ce lethal (2) 57Ce http://flybase.org/reports/FBgn0002099 - gene - - - "l(2)57CDa, l(2)57Ce" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030410 Aven Apoptosis and caspase activation inhibitor http://flybase.org/reports/FBgn0030410 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of G2/M transition of mitotic cell cycle ; GO:0010972 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG15727, Aven, dAven" IPR026187:Cell death regulator Aven CG15727 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,mitotic cell cycle defective,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,lethal,temperature conditional,viable" "ovary,adult fat body" FBgn0045849 l(4)102Fd lethal (4) 102Fd http://flybase.org/reports/FBgn0045849 gene - - - l(4)102Fd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032886 CG9328 - http://flybase.org/reports/FBgn0032886 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cell growth ; GO:0001558 | inferred from sequence or structural similarity with HGNC:30827 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:30827 "38E.22, LD01639, BEST:LD01639, BcDNA:SD01241, CG9328" IPR009533:Protein of unknown function DUF1151 CG9328 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-160o17.6, Drer\fam107b, Drer\fam107a, Drer\si:ch211-218o21.4, Drer\zgc:195245, Drer\si:ch211-236d3.4" - Cele\Y82E9BR.4 "Xtro\fam107a, Xtro\fam107b" "Mmus\Fam107a, Mmus\Fam107b" "Hsap\FAM107B, Hsap\FAM107A" viable FBgn0062253 Su(dpp)YE10 Su(dpp)YE10 http://flybase.org/reports/FBgn0062253 gene - - - Su(dpp)YE10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "denticle belt,amnioserosa,abdominal 4 ventral denticle belt" FBgn0029766 CG15784 - http://flybase.org/reports/FBgn0029766 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15784 IPR011989:Armadillo-like helical CG15784 11-Aug-17 DroID_v2017_08 - - Cele\abf-6 - - - "viable,fertile,lethal,recessive,partially lethal - majority die,visible" mesothoracic tergum FBgn0032048 Dh31 Diuretic hormone 31 http://flybase.org/reports/FBgn0032048 protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with Dh31-R diuretic hormone activity ; GO:0008613 | inferred from direct assay diuretic hormone activity ; GO:0008613 | non-traceable author statement neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity "positive regulation of circadian sleep/wake cycle, wakefulness ; GO:0010841 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay body fluid secretion ; GO:0007589 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from sequence or structural similarity positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010579 | inferred from direct assay" extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "DH31, drome-DH31, DH-II, CG13094, Drome-DH[[31]], Drm-DH[[31]], anon-EST:Posey114, anon-WO02059370.45, Dh31, dh31, DH 31, DH[[31], Dh[[31]], DH[[31]], DH[31]" IPR034439:Peptide hormone DH31-like CG13094 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0016768 l(1)1Bl lethal (1) 1Bl http://flybase.org/reports/FBgn0016768 - gene - - - "anon-1Bd, l(1)1Bl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065395 l(2)SH1616 lethal (2) SH1616 http://flybase.org/reports/FBgn0065395 gene - - - "l(2)SH1616, l(2)SH2 1616" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035120 wac wee Augmin http://flybase.org/reports/FBgn0035120 protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with dgt2 spindle assembly involved in female meiosis ; GO:0007056 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype cell division ; GO:0051301 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay HAUS complex ; GO:0070652 | colocalizes_with inferred from direct assay meiotic spindle ; GO:0072687 | inferred from direct assay protein complex ; GO:0043234 | inferred from direct assay inferred from genetic interaction with dgt2 spindle ; GO:0005819 | inferred from direct assay "wac, Wac, was, CG13879, Dgt8" - CG13879 11-Aug-17 DroID_v2017_08 - - - - - - "viable,mitotic cell cycle defective,female sterile" "oocyte,meiotic spindle,spindle pole,eye,macrochaeta,adult cuticle,chromosome,spindle" FBgn0085749 CR40574 - http://flybase.org/reports/FBgn0085749 rRNA_gene - - - CR40574 - CR40574 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027080 TyrRS Tyrosyl-tRNA synthetase http://flybase.org/reports/FBgn0027080 "FBgn0025537, FBgn0036630" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002305, InterPro:IPR002307 tyrosine-tRNA ligase activity ; GO:0004831 | traceable author statement tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 tyrosine-tRNA ligase activity ; GO:0004831 | inferred from direct assay chemoattractant activity ; GO:0042056 | inferred from direct assay inferred from mutant phenotype" tyrosyl-tRNA aminoacylation ; GO:0006437 | inferred from electronic annotation with InterPro:IPR002307 regulation of macrophage chemotaxis ; GO:0010758 | inferred from direct assay inferred from mutant phenotype tyrosyl-tRNA aminoacylation ; GO:0006437 | traceable author statement positive chemotaxis ; GO:0050918 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement extracellular space ; GO:0005615 | inferred from direct assay methionyl glutamyl tRNA synthetase complex ; GO:0017102 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 "Aats-tyr, CG4561, TyrRS, YRS, anon-EST:Posey261, dTyrRS, dYARS, YARS" "IPR002305:Aminoacyl-tRNA synthetase, class Ic, IPR002307:Tyrosine-tRNA ligase, IPR002547:tRNA-binding domain, IPR012340:Nucleic acid-binding, OB-fold, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG4561 11-Aug-17 DroID_v2017_08 "Drer\yars, Drer\zgc:101853, Drer\aimp1" "Scer\ARC1, Scer\TYS1" Cele\yars-1 "Xtro\aimp1, Xtro\yars" "Mmus\Yars, Mmus\Aimp1" "Hsap\YARS, Hsap\AIMP1" embryonic stage "

ubiquitous , embryonic/larval salivary gland

" "locomotor behavior defective,lethal,partially lethal - majority die,viable,decreased cell size,cell autonomous,somatic clone" "lysosome & larval fat body | somatic clone | cell autonomous,scutellar bristle" DRSC10430 I -1.817513107 0.79666709 0.800816708 0.562389039 0.025846277 -0.196815075 FBgn0069442 E(zip)12-5 E(zip)12-5 http://flybase.org/reports/FBgn0069442 gene - - - "12-5, E(zip)12-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259955 CG42465 - http://flybase.org/reports/FBgn0259955 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG42465 IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42465 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259606 B0216 - http://flybase.org/reports/FBgn0259606 gene - - - B0216 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "antennal segment,leg,arista" FBgn0266681 CR45171 - http://flybase.org/reports/FBgn0266681 non_protein_coding_gene - - - CR45171 - CR45171 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013676 mt:CoIII mitochondrial Cytochrome c oxidase subunit III http://flybase.org/reports/FBgn0013676 FBgn0002867 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from electronic annotation with InterPro:IPR013833 aerobic electron transport chain ; GO:0019646 | inferred from electronic annotation with InterPro:IPR024791 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000298, InterPro:IPR013833, InterPro:IPR024791" "CG34074, COX, CO III, III, COIII, CO, mt:CoIII, CO3, COXIII, cox3, mt-CO3, CcO subunit III, Co III, COX III, CcO III, coxIII, COX3, mt:Cox3, CoIII, Co-III" "IPR000298:Cytochrome c oxidase-like subunit III, IPR013833:Cytochrome c oxidase, subunit III, 4-helical bundle, IPR033945:Cytochrome c oxidase subunit III domain, IPR024791:Cytochrome c oxidase subunit III" CG34074 11-Aug-17 DroID_v2017_08 Drer\COX3 "Scer\cox3, Scer\COX3" Cele\COX3 Xtro\COX3 Mmus\COX3 Hsap\COX3 FBgn0023472 anon-30Fb anon-30Fb http://flybase.org/reports/FBgn0023472 - gene - - - anon-30Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005446 l(1)v216 lethal (1) v216 http://flybase.org/reports/FBgn0005446 - gene - - - "l(1)216, l(1)v216" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051497 tRNA:Thr-AGT-1-3 transfer RNA:Threonine-AGT 1-3 http://flybase.org/reports/FBgn0051497 tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "AE002708.trna52-ThrAGT, tRNA:T:AGT:AE002708-e, CR31497, tRNA[[Thr]], chr3R.trna58-ThrAGT, tRNA-Thr-AGT-1-3, tRNA:Thr-AGT-1-3, tRNA:CR31497, ACU" - CR31497 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027242 l(1)G0270 lethal (1) G0270 http://flybase.org/reports/FBgn0027242 - gene - - - l(1)G0270 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053557 CG33557 - http://flybase.org/reports/FBgn0053557 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with da" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with da" nucleus ; GO:0005634 | inferred by curator from GO:0003700 "CG12648, CG33557" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG33557 11-Aug-17 DroID_v2017_08 "Drer\mespab, Drer\figla, Drer\nhlh2, Drer\msc, Drer\hand2, Drer\mespaa, Drer\tcf24, Drer\tcf23, Drer\scxa, Drer\msgn1, Drer\tal2, Drer\tcf21, Drer\tal1, Drer\scxb, Drer\atoh1c, Drer\si:ch211-246m6.4, Drer\ascl1b, Drer\tcf15, Drer\lyl1, Drer\ptf1a, Drer\ascl1a, Drer\mespba" - "Cele\hlh-17, Cele\hlh-12, Cele\hlh-19, Cele\hlh-16, Cele\hlh-15, Cele\hlh-3, Cele\hlh-13, Cele\hlh-32, Cele\hlh-31, Cele\lin-32" "Xtro\msgn1, Xtro\lyl1, Xtro\scx, Xtro\ptf1a, Xtro\hand1, Xtro\ascl2, Xtro\tcf21, Xtro\nhlh1, Xtro\hand2, Xtro\tcf15, Xtro\msc, Xtro\ascl3, Xtro\tal1, Xtro\figla, Xtro\mespb, Xtro\mespa" "Mmus\Figla, Mmus\Nhlh2, Mmus\Ascl4, Mmus\Tcf23, Mmus\Ascl5, Mmus\Msgn1, Mmus\Mesp2, Mmus\Hand2, Mmus\Hand1, Mmus\Scx, Mmus\Msc, Mmus\Tal2, Mmus\Ferd3l, Mmus\Ascl1, Mmus\Mesp1, Mmus\Ascl3, Mmus\Lyl1, Mmus\Nhlh1, Mmus\Tcf15, Mmus\Ptf1a, Mmus\Tal1, Mmus\Tcf21" "Hsap\MSC, Hsap\TCF21, Hsap\ASCL1, Hsap\MESP2, Hsap\HAND2, Hsap\FIGLA, Hsap\HAND1, Hsap\TCF24, Hsap\TAL1, Hsap\ASCL3, Hsap\TCF15, Hsap\ASCL5, Hsap\TAL2, Hsap\MESP1, Hsap\TCF23, Hsap\ASCL4, Hsap\MSGN1, Hsap\PTF1A, Hsap\NHLH2, Hsap\SCX, Hsap\LYL1, Hsap\NHLH1" viable FBgn0082335 HM781 HM781 http://flybase.org/reports/FBgn0082335 gene - - - HM781 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040218 fs(2)BP76 fs(2)BP76 http://flybase.org/reports/FBgn0040218 gene - - - fs(2)BP76 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0003690 telegraph telegraph http://flybase.org/reports/FBgn0003690 - gene - - - "tg, telegraph" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing vein L2,posterior scutellar bristle" FBgn0000201 bn band http://flybase.org/reports/FBgn0000201 - gene - - - bn - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "trident,adult thorax,microchaeta & thorax" FBgn0034595 CG15657 - http://flybase.org/reports/FBgn0034595 protein_coding_gene - - - "BcDNA:AT24036, CG15657" - CG15657 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263204 HipHop::ms(3)K81 - http://flybase.org/reports/FBgn0263204 engineered_fusion_gene - - - "hiphop-k81, HipHop::ms(3)K81" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036570 IntS9 Integrator 9 http://flybase.org/reports/FBgn0036570 protein_coding_gene - snRNA 3'-end processing ; GO:0034472 | inferred from direct assay mRNA polyadenylation ; GO:0006378 | inferred from sequence or structural similarity with protein_id:BAA91867 snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:25592 mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with protein_id:BAA91867 integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:25592 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from sequence or structural similarity with protein_id:BAA91867 "CG5222, IntS9, Ints9, Int9" "IPR001279:Metallo-beta-lactamase, IPR027074:Integrator complex subunit 9, IPR022712:Beta-Casp domain" CG5222 11-Aug-17 DroID_v2017_08 Drer\ints9 - Cele\F19F10.12 Xtro\ints9 Mmus\Ints9 Hsap\INTS9 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0000621 e(y)5 enhancer of yellow 5 http://flybase.org/reports/FBgn0000621 - gene - - - e(y)5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,visible" "head bristle,macrochaeta,microchaeta" FBgn0010280 Taf4 TBP-associated factor 4 http://flybase.org/reports/FBgn0010280 "FBgn0005542, FBgn0010419, FBgn0013958" protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf12 DNA binding ; GO:0003677 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Dlip3 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000388601 TFIIA-class transcription factor binding ; GO:0001092 | inferred from physical interaction with TfIIA-L" "transcription from RNA polymerase II promoter ; GO:0006366 | inferred from physical interaction with UniProtKB:P51123 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from physical interaction with UniProtKB:P51123 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay regulation of transcription, DNA-templated ; GO:0006355 | inferred from physical interaction with UniProtKB:P51123 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11537 inferred from sequence or structural similarity with SGD:S000004607 muscle organ development ; GO:0007517 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11537 inferred from sequence or structural similarity with SGD:S000004607 transcription factor TFIID complex ; GO:0005669 | inferred from physical interaction with Taf6 transcription factor TFIID complex ; GO:0005669 | inferred from physical interaction with UniProtKB:P51123 "dTAF[[II]]110, TAFII110, TAF[[II]]110, dmTAF4, dTAF4, TAF110, Taf110, TAF, TFIID, taf110, TAF[[II]], TAF[II]110, TAF4, dTAFII110, d110, CG5444, SY3-2 TAF110, TFIID 110, SR3-3, Taf[[II]]110, p110, l(3)72Dj, Taf4" "IPR003894:TAFH/NHR1, IPR009072:Histone-fold, IPR015943:WD40/YVTN repeat-like-containing domain, IPR007900:Transcription initiation factor TFIID component TAF4" CG5444 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-219c3.2, Drer\taf4b, Drer\LOC101885225, Drer\taf4a" Scer\TAF4 Cele\taf-4 Xtro\taf4 "Mmus\Taf4b, Mmus\Taf4" "Hsap\TAF4, Hsap\TAF4B" "lethal,recessive,cell cycle defective,somatic clone,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of P-stage,some die during pharate adult stage" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast,ganglion mother cell" DRSC11297 IEK -2.292296628 0.766085108 -2.123428118 -0.381937944 1.830149585 0.906543716 FBgn0051768 CG31768 - http://flybase.org/reports/FBgn0051768 protein_coding_gene - - - "BcDNA:RH43029, CG31768" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028649 anon-55Ec anon-55Ec http://flybase.org/reports/FBgn0028649 gene - - - "E-2000, D-1700, anon-55Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010482 l(2)01289 lethal (2) 01289 http://flybase.org/reports/FBgn0010482 "FBgn0013956, FBgn0033098, FBgn0033099, FBgn0050444" protein_coding_gene - cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 - "l(2)01289, CG9432, CG30444, CG9435" "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain" CG9432 11-Aug-17 DroID_v2017_08 "Drer\txndc16, Drer\erp27, Drer\dnajc10, Drer\txndc5, Drer\pdia6" "Scer\MPD1, Scer\MPD2, Scer\EPS1" Cele\D2092.4 "Xtro\txndc5, Xtro\pdia6, Xtro\txndc16" "Mmus\Pdia6, Mmus\Erp27, Mmus\Txndc5, Mmus\Txndc16, Mmus\Dnajc10, Mmus\Pdia5" "Hsap\TXNDC16, Hsap\ERP27, Hsap\PDILT, Hsap\PDIA6, Hsap\PDIA5, Hsap\DNAJC10, Hsap\TXNDC5" "lethal,recessive,viable" FBgn0033819 CG4714 - http://flybase.org/reports/FBgn0033819 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.159, CG4714" IPR025254:Domain of unknown function DUF4201 CG4714 11-Aug-17 DroID_v2017_08 Drer\ccdc96 - - - Mmus\Ccdc96 Hsap\CCDC96 viable FBgn0060345 l(3)S143517 lethal (3) S143517 http://flybase.org/reports/FBgn0060345 gene - - - "1435/17, l(3)S143517" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0001101 ge genitalless http://flybase.org/reports/FBgn0001101 - gene - - - "gen, ge" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,viable,visible,melanotic mass phenotype,male" "male genitalia,macrochaeta,wing,melanotic mass,tergite" FBgn0082976 snoRNA:Psi28S-3305a snoRNA:Psi28S-3305a http://flybase.org/reports/FBgn0082976 snoRNA_gene - - - "snoRNA:Psi28S-3305a, psi28s-3305a, Psi 28S-3305a, CR34619" - CR34619 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028943 CG15638 - http://flybase.org/reports/FBgn0028943 protein_coding_gene - - - "BG:BACR48E02.1, CG15638" - CG15638 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004036 yea2 yeast 2 http://flybase.org/reports/FBgn0004036 - gene - - - yea2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000714 fmf factor for male fertility http://flybase.org/reports/FBgn0000714 - gene - - - fmf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000491 droopy droopy http://flybase.org/reports/FBgn0000491 - gene - - - "droopy, dr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile" "wing,alula" FBgn0069409 JJF177 JJF177 http://flybase.org/reports/FBgn0069409 gene - - - JJF177 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0265957 CR44744 - http://flybase.org/reports/FBgn0265957 non_protein_coding_gene - - - CR44744 - CR44744 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085734 CR40450 - http://flybase.org/reports/FBgn0085734 pseudogene_attribute - - - CR40450 - CR40450 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265887 CR44676 - http://flybase.org/reports/FBgn0265887 non_protein_coding_gene - - - CR44676 - CR44676 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033537 CG11834 - http://flybase.org/reports/FBgn0033537 protein_coding_gene - - - CG11834 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265070 CR44181 - http://flybase.org/reports/FBgn0265070 non_protein_coding_gene - - - CR44181 - CR44181 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037076 ebd2 earthbound 2 http://flybase.org/reports/FBgn0037076 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - "ebd2, CG12972" "IPR007889:DNA binding HTH domain, Psq-type, IPR006600:HTH CenpB-type DNA-binding domain, IPR009057:Homeobox domain-like" CG12972 11-Aug-17 DroID_v2017_08 Drer\LOC100150296 - Cele\F21D5.4 - - - "viable,fertile" dorsal medial muscle FBgn0065203 l(2)SH2288 lethal (2) SH2288 http://flybase.org/reports/FBgn0065203 gene - - - l(2)SH2288 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034249 RhoGAP54D Rho GTPase activating protein at 54D http://flybase.org/reports/FBgn0034249 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with SGD:S000005660 imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype small GTPase mediated signal transduction ; GO:0007264 | inferred from sequence or structural similarity with SGD:S000005660 cellular_component ; GO:0005575 | no biological data available "CG6477, RhoGAP54D" "IPR000198:Rho GTPase-activating protein domain, IPR008936:Rho GTPase activation protein" CG6477 11-Aug-17 DroID_v2017_08 "Drer\arhgap19, Drer\arhgap28" Scer\LRG1 - "Xtro\arhgap18, Xtro\arhgap19, Xtro\arhgap28" "Mmus\Arhgap19, Mmus\Stard13" "Hsap\ARHGAP19, Hsap\SLIT1" viable FBgn0031719 CG18269 - http://flybase.org/reports/FBgn0031719 protein_coding_gene - - - CG18269 IPR007970:Protein of unknown function DUF733 CG18269 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265264 CG17097 - http://flybase.org/reports/FBgn0265264 protein_coding_gene lipase activity ; GO:0016298 | inferred from sequence or structural similarity multicellular organism reproduction ; GO:0032504 | inferred from expression pattern lipid metabolic process ; GO:0006629 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG17097, anon-SAGE:Wang-018" "IPR029058:Alpha/Beta hydrolase fold, IPR000073:Alpha/beta hydrolase fold-1" CG17097 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\TGL1, Scer\YEH1, Scer\YEH2" "Cele\lipl-3, Cele\lipl-6, Cele\lipl-7, Cele\lipl-4, Cele\lipl-2, Cele\lipl-1, Cele\lipl-5, Cele\lipl-8" Xtro\lipa "Mmus\Lipf, Mmus\Lipa, Mmus\Lipo3, Mmus\Lipo4, Mmus\Lipo2, Mmus\Lipm, Mmus\Lipo1, Mmus\Lipn, Mmus\Lipk" "Hsap\LIPK, Hsap\LIPN, Hsap\LIPA, Hsap\LIPM, Hsap\LIPF, Hsap\LIPJ" FBgn0065806 l(2)SH0394 lethal (2) SH0394 http://flybase.org/reports/FBgn0065806 gene - - - "l(2)SH0394, l(2)SH2 0394" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036428 Gbs-70E Glycogen binding subunit 70E http://flybase.org/reports/FBgn0036428 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B glycogen binding ; GO:2001069 | inferred from direct assay behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype regulation of glycogen metabolic process ; GO:0070873 | inferred from mutant phenotype - "Gbs-70E, anon-WO0118547.400, CG9238" "IPR005036:CBM21 (carbohydrate binding type-21) domain, IPR017434:Protein phosphatase 1 regulatory subunit 3B/C/D, metazoa, IPR013783:Immunoglobulin-like fold" CG9238 11-Aug-17 DroID_v2017_08 "Drer\ppp1r3db, Drer\ppp1r3ab, Drer\zgc:77112, Drer\si:dkey-242g16.2, Drer\ppp1r3ca, Drer\ppp1r3b, Drer\ppp1r3aa, Drer\ppp1r3cb, Drer\ppp1r3da" "Scer\PIG1, Scer\PIG2, Scer\GIP2, Scer\GAC1" "Cele\H18N23.2, Cele\CC8.2" "Xtro\ppp1r3b, Xtro\ppp1r3c.1, Xtro\ppp1r3c.2" "Mmus\Ppp1r3c, Mmus\Ppp1r3d, Mmus\Ppp1r3b, Mmus\Ppp1r3g, Mmus\Ppp1r3f, Mmus\Ppp1r3a, Mmus\Ppp1r3e" "Hsap\PPP1R3C, Hsap\PPP1R3G, Hsap\PPP1R3F, Hsap\PPP1R3D, Hsap\PPP1R3B, Hsap\PPP1R3E, Hsap\PPP1R3A" "hyperactive,conditional,chemical resistant,short lived,female semi-sterile,viable" FBgn0037491 CG1227 - http://flybase.org/reports/FBgn0037491 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000539981 protein kinase activity ; GO:0004672 | non-traceable author statement positive regulation of cell size ; GO:0045793 | inferred from genetic interaction with gig protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000539981 protein phosphorylation ; GO:0006468 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000540112 "MPSK/PSK, CG1227, Psk" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG1227 11-Aug-17 DroID_v2017_08 Drer\stk16 Scer\ENV7 "Cele\D2045.7, Cele\tag-257" Xtro\stk16 Mmus\Stk16 Hsap\STK16 viable FBgn0028537 CG31775 - http://flybase.org/reports/FBgn0028537 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BG:DS00810.2, BcDNA:LP08165, BcDNA:RH25462, BcDNA:RE38252, CG31775" - CG31775 11-Aug-17 DroID_v2017_08 - - - - - - DRSC01413 IK -1.519455633 -1.062312123 -1.334795566 -0.953429441 -0.813126301 1.522373458 FBgn0033285 CG18449 - http://flybase.org/reports/FBgn0033285 protein_coding_gene - - - CG18449 "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG18449 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264895 RapGAP1 Rap GTPase activating protein 1 http://flybase.org/reports/FBgn0264895 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from direct assay inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype negative regulation of small GTPase mediated signal transduction ; GO:0051058 | inferred from direct assay germ plasm ; GO:0060293 | inferred from direct assay "RapGAP1, CG44086, Rapgap1, CG34374, CG6682, CG13789, CG33529, CG13790, RapGap1, rapgap1, CG13791, Q9VM02_DROME, FBpp0111515, rapgap" "IPR008979:Galactose-binding domain-like, IPR003109:GoLoco motif, IPR000331:Rap GTPase activating protein domain" CG44086 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001168, Drer\LOC101882292, Drer\rap1gap2a, Drer\si:ch1073-90m23.1, Drer\sipa1l3, Drer\si:dkey-166d12.2, Drer\rap1gap, Drer\sipa1l1, Drer\si:ch211-182d3.1, Drer\sipa1l2, Drer\rap1gap2b, Drer\ralgapa2" - Cele\F53A10.2 "Xtro\rap1gap2, Xtro\tsc2, Xtro\sipa1l1, Xtro\ralgapa1, Xtro\rap1gap, Xtro\garnl3" "Mmus\Sipa1l3, Mmus\Sipa1l1, Mmus\Ralgapa1, Mmus\Garnl3, Mmus\Sipa1l2, Mmus\Ralgapa2, Mmus\Sipa1, Mmus\Rap1gap2, Mmus\Rap1gap, Mmus\Tsc2" "Hsap\RAP1GAP, Hsap\SIPA1L2, Hsap\GARNL3, Hsap\RAP1GAP2, Hsap\TSC2, Hsap\SIPA1, Hsap\RALGAPA2, Hsap\SIPA1L3, Hsap\RALGAPA1, Hsap\SIPA1L1" " larval stage , embryonic stage | stage >12 , embryonic stage | early , embryonic stage | stage 8-11 " " ommatidial precursor cluster

, garland cell

, embryonic peripheral nervous system

, pole cell

, embryonic/larval midgut

, larval optic lobe

, morphogenetic furrow

, ventral neurogenic region

, optic nerve

, morphogenetic furrow | posterior to

, eye disc

" DRSC02293 K -0.569615305 -0.295575372 -0.327940078 0.394825394 -1.559783334 -0.69270326 FBgn0043479 l(3)66EFg lethal (3) 66EFg http://flybase.org/reports/FBgn0043479 gene - - - l(3)66EFg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067765 l(1)16-1-27 lethal (1) 16-1-27 http://flybase.org/reports/FBgn0067765 gene - - - l(1)16-1-27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065959 l(2)SH0042 lethal (2) SH0042 http://flybase.org/reports/FBgn0065959 gene - - - "l(2)SH0042, l(2)SH2 0042" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033117 CG3358 - http://flybase.org/reports/FBgn0033117 protein_coding_gene "endodeoxyribonuclease activity, producing 5'-phosphomonoesters ; GO:0016888 | inferred from electronic annotation with InterPro:IPR001130, InterPro:IPR018228 deoxyribonuclease activity ; GO:0004536 | inferred from biological aspect of ancestor with PANTHER:PTN000006754" DNA catabolic process ; GO:0006308 | inferred from biological aspect of ancestor with PANTHER:PTN000006754 - CG3358 "IPR001130:TatD family, IPR018228:Deoxyribonuclease, TatD-related, conserved site, IPR032466:Metal-dependent hydrolase" CG3358 11-Aug-17 DroID_v2017_08 "Drer\tatdn3, Drer\LOC571912, Drer\tatdn2, Drer\tatdn1" "Scer\YMR262W, Scer\YBL055C" "Cele\crn-2, Cele\Y37H2A.1, Cele\Y24F12A.1, Cele\B0432.8" Xtro\tatdn1 "Mmus\Tatdn2, Mmus\Tatdn3, Mmus\Tatdn1" "Hsap\TATDN1, Hsap\TATDN3, Hsap\TATDN2" "partially lethal - majority die,some die during pupal stage" FBgn0035184 CG9094 - http://flybase.org/reports/FBgn0035184 protein_coding_gene - - - CG9094 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083295 E(smoDN)1889 Enhancer of smoDN 1889 http://flybase.org/reports/FBgn0083295 gene - - - E(smoDN)1889 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265987 CR44766 - http://flybase.org/reports/FBgn0265987 non_protein_coding_gene - - - CR44766 - CR44766 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259936 Uhg3 Uhg3 http://flybase.org/reports/FBgn0259936 non_protein_coding_gene - - - "Uhg3, dUhg3, CR32957, BcDNA:GH14469, pncr012:2L, GH14469" - CR32957 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027212 l(1)G0346 lethal (1) G0346 http://flybase.org/reports/FBgn0027212 - gene - - - l(1)G0346 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0264747 CG44005 - http://flybase.org/reports/FBgn0264747 protein_coding_gene - - - "CG44005, CG34252" "IPR032675:Leucine-rich repeat domain, L domain-like" CG44005 11-Aug-17 DroID_v2017_08 - - "Cele\C34F6.9, Cele\T01E8.1" - - - FBgn0000720 fol folded wings http://flybase.org/reports/FBgn0000720 - gene - - - fol - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0030738 CG9915 - http://flybase.org/reports/FBgn0030738 protein_coding_gene - "regulation of mRNA processing ; GO:0050684 | inferred from biological aspect of ancestor with PANTHER:PTN001114632 regulation of histone H3-K36 trimethylation ; GO:2001253 | inferred from biological aspect of ancestor with PANTHER:PTN001114632 regulation of DNA-templated transcription, elongation ; GO:0032784 | inferred from biological aspect of ancestor with PANTHER:PTN001114632 regulation of mRNA export from nucleus ; GO:0010793 | inferred from biological aspect of ancestor with PANTHER:PTN001114632" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001114632 CG9915 "IPR017923:Transcription factor IIS, N-terminal" CG9915 11-Aug-17 DroID_v2017_08 Drer\iws1 Scer\SPN1 Cele\F13B12.1 Xtro\iws1 Mmus\Iws1 Hsap\IWS1 DRSC21565 K 0.455239793 0.24318825 0.689885855 1.032420403 -0.274329083 2.035005342 FBgn0023428 lad ladybird http://flybase.org/reports/FBgn0023428 - gene - - - lad - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "pigment cell,eye" FBgn0086023 snoRNA:Me28S-A2589a - http://flybase.org/reports/FBgn0086023 snoRNA_gene - - - "snoRNA:Me28S-A2589a, Me28S-Am2589a, Me28S-A2589a, CR34652" - CR34652 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0285925 Fas1 Fasciclin 1 http://flybase.org/reports/FBgn0285925 protein_coding_gene cell adhesion molecule binding ; GO:0050839 | inferred from direct assay neuron recognition ; GO:0008038 | inferred from direct assay axon guidance ; GO:0007411 | inferred from genetic interaction with Abl calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules ; GO:0016338 | inferred from direct assay homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG6588, fas1, Fas1, DROFASI, FasI, Fas I, fasI, DROFAS, DROFAS1, fas-I, gasI, fas I, MRE24, FGM222E05" IPR000782:FAS1 domain CG6588 11-Aug-17 DroID_v2017_08 "Drer\postna, Drer\postnb, Drer\tgfbi" Scer\YLR001C Cele\F26E4.7 "Xtro\tgfbi, Xtro\postn" "Mmus\Tgfbi, Mmus\Postn" "Hsap\POSTN, Hsap\TGFBI" FBgn0036609 CG13039 - http://flybase.org/reports/FBgn0036609 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT27312, CG13039" - CG13039 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC09920 I 1.819788267 -0.326099151 0.685699411 0.938916328 -0.169303213 -0.551693835 FBgn0085559 CG41038 - http://flybase.org/reports/FBgn0085559 protein_coding_gene - - - CG41038 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031559 CG3513 - http://flybase.org/reports/FBgn0031559 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG3513 "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG3513 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-117n7.5, Drer\ambp, Drer\aplp2, Drer\tfpia, Drer\spint1a, Drer\tfpi2, Drer\col6a4a, Drer\spint2, Drer\spint1b, Drer\si:dkeyp-73b11.8" - "Cele\apl-1, Cele\C34F6.1, Cele\Y43F8B.3, Cele\tag-290" "Xtro\tfpi2, Xtro\app, Xtro\spint1, Xtro\spint2, Xtro\ambp" "Mmus\App, Mmus\Wfdc6a, Mmus\Spint5, Mmus\Ambp, Mmus\Col6a3, Mmus\Wfdc8, Mmus\Spint2, Mmus\Spint3, Mmus\Spint4, Mmus\Aplp2, Mmus\Spint1, Mmus\Aplp1, Mmus\Tfpi2, Mmus\Tfpi, Mmus\Eppin, Mmus\Wfdc6b" "Hsap\WFDC8, Hsap\SPINT4, Hsap\EPPIN-WFDC6, Hsap\TFPI2, Hsap\COL6A3, Hsap\APLP2, Hsap\APP, Hsap\AMBP, Hsap\SPINT1, Hsap\WFDC6, Hsap\APLP1, Hsap\SPINT2, Hsap\TFPI, Hsap\WFIKKN1, Hsap\SPINT3" "partially lethal - majority die,some die during pupal stage" FBgn0029714 CG3527 - http://flybase.org/reports/FBgn0029714 protein_coding_gene rRNA (pseudouridine) methyltransferase activity ; GO:0070037 | inferred from sequence or structural similarity with SGD:S000004176 rRNA (pseudouridine) methyltransferase activity ; GO:0070037 | inferred from sequence or structural similarity with UniProtKB:Q92979 rRNA (pseudouridine) methyltransferase activity ; GO:0070037 | inferred from biological aspect of ancestor with PANTHER:PTN000290839 rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000290839 "rRNA base methylation ; GO:0070475 | inferred from biological aspect of ancestor with PANTHER:PTN000290839 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000290839 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype rRNA methylation ; GO:0031167 | inferred from sequence or structural similarity with SGD:S000004176 neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000290839 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000290839 "CG3527, dNEP1" "IPR005304:Ribosomal biogenesis, methyltransferase, EMG1/NEP1, IPR029028:Alpha/beta knot methyltransferases" CG3527 11-Aug-17 DroID_v2017_08 Drer\emg1 Scer\EMG1 Cele\Y39A1A.14 Xtro\emg1 Mmus\Emg1 Hsap\EMG1 "viable,fertile,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0262519 Mi-2 Mi-2 http://flybase.org/reports/FBgn0262519 protein_coding_gene "ATP-dependent helicase activity ; GO:0008026 | inferred from electronic annotation with InterPro:IPR002464 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR002464, InterPro:IPR012957, InterPro:IPR012958 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965, InterPro:IPR012957, InterPro:IPR012958 helicase activity ; GO:0004386 | inferred from sequence or structural similarity chromatin binding ; GO:0003682 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay nucleosome-dependent ATPase activity ; GO:0070615 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with simj ATPase activity ; GO:0016887 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model nucleosome binding ; GO:0031491 | inferred from direct assay nucleosome-dependent ATPase activity ; GO:0070615 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with MEP-1 ATP-dependent DNA helicase activity ; GO:0004003 | inferred from sequence or structural similarity" "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with UniProtKB:P05084 ATP-dependent chromatin remodeling ; GO:0043044 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype chromosome decondensation ; GO:0051312 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype negative regulation of cohesin loading ; GO:0071923 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay nucleosome mobilization ; GO:0042766 | inferred from direct assay muscle organ development ; GO:0007517 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" transcriptionally active chromatin ; GO:0035327 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay NuRD complex ; GO:0016581 | inferred from sequence or structural similarity polytene chromosome ; GO:0005700 | inferred from direct assay NuRD complex ; GO:0016581 | traceable author statement cytosol ; GO:0005829 | inferred from direct assay "CG8103, Mi-2, dMi-2, Chd4, l(3)76BDe, Mi2, dMi, dMI-2, MI2, Mi 2, Pha, Dm-Mi-2, l(3)S085401, l(3)S000606, hip76, l(3)A154.3M3, 0854/01, 0006/06, pha, l(3)j3D4, l(3)01058, dMi2, MI-2, l(3)L1243, M-i2" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR009071:High mobility group box domain, IPR000330:SNF2-related, N-terminal domain, IPR000953:Chromo/chromo shadow domain, IPR001650:Helicase, C-terminal, IPR001965:Zinc finger, PHD-type, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR009462:Domain of unknown function DUF1086, IPR009463:Domain of unknown function DUF1087, IPR011011:Zinc finger, FYVE/PHD-type, IPR012957:CHD, C-terminal 2, IPR012958:CHD, N-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR016197:Chromo domain-like, IPR019787:Zinc finger, PHD-finger, IPR019786:Zinc finger, PHD-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR023780:Chromo domain" CG8103 11-Aug-17 DroID_v2017_08 "Drer\smarca1, Drer\smarca5, Drer\chd6, Drer\phf21b, Drer\chd3, Drer\chd5, Drer\chd4a, Drer\phf21ab, Drer\phf21aa, Drer\chd4b" "Scer\CHD1, Scer\ISW1, Scer\ISW2" "Cele\let-418, Cele\isw-1, Cele\chd-3" "Xtro\chd4, Xtro\smarca5, Xtro\chd8, Xtro\chd5, Xtro\chd3, Xtro\smarca1" "Mmus\Smarca5, Mmus\Chd4, Mmus\Chd3, Mmus\Chd5, Mmus\Chd6, Mmus\Chd2, Mmus\Chd1, Mmus\Phf21b, Mmus\Chd8, Mmus\Smarca1" "Hsap\CHD6, Hsap\CHD3, Hsap\CHD5, Hsap\SMARCA1, Hsap\CHD8, Hsap\CHD4, Hsap\CHD1, Hsap\SMARCA5, Hsap\CHD2" embryonic stage DRSC11222 IEK -1.958727306 -0.520254985 -1.855189637 -0.125224747 2.174374019 4.602912116 FBgn0015334 anon-100Aa anon-100Aa http://flybase.org/reports/FBgn0015334 - gene - - - "T1, anon-100Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011159 l(1)Q237 lethal (1) Q237 http://flybase.org/reports/FBgn0011159 FBgn0010210 gene - - - l(1)Q237 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261291 CheA86a Chemosensory protein A 86a http://flybase.org/reports/FBgn0261291 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheA29a extracellular region ; GO:0005576 | inferred from sequence model "CG33698, CheA86a" IPR010512:Protein of unknown function DUF1091 CG33698 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062522 l(3)ff29 lethal (3) ff29 http://flybase.org/reports/FBgn0062522 gene - - - l(3)ff29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0002537 Lcp6 Larval cuticle protein 6 http://flybase.org/reports/FBgn0002537 - gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 - - "LCP6, L[[3]]CP6, Lcp6" IPR000618:Insect cuticle protein - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0022041 l(2)k08317 lethal (2) k08317 http://flybase.org/reports/FBgn0022041 - gene - - - l(2)k08317 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267112 CR45552 - http://flybase.org/reports/FBgn0267112 non_protein_coding_gene - - - CR45552 - CR45552 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032943 Tsp39D Tetraspanin 39D http://flybase.org/reports/FBgn0032943 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG8666, Dm.Tsp39D, Tsp39D" "IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain, IPR018499:Tetraspanin/Peripherin" CG8666 11-Aug-17 DroID_v2017_08 "Drer\tspan4b, Drer\tspan11, Drer\tspan7b, Drer\cd151l, Drer\cd151, Drer\tspan7, Drer\cd63" - "Cele\tsp-2, Cele\tsp-1, Cele\tsp-7, Cele\tsp-14, Cele\tsp-3" "Xtro\tspan6, Xtro\cd63, Xtro\cd151" "Mmus\Tspan7, Mmus\Tspan6, Mmus\Cd63, Mmus\Cd151, Mmus\Tspan11" "Hsap\CD63, Hsap\TSPAN7, Hsap\TSPAN11, Hsap\TSPAN6, Hsap\CD151" viable FBgn0050275 CG30275 - http://flybase.org/reports/FBgn0050275 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 - "CG13520, CG30275" "IPR023753:FAD/NAD(P)-binding domain, IPR032151:Cilia- and flagella-associated protein 61, N-terminal domain" CG30275 11-Aug-17 DroID_v2017_08 - - - Xtro\cfap61 Mmus\Cfap61 Hsap\CFAP61 "partially lethal - majority die,some die during pupal stage" FBgn0038398 sxe2 sex-specific enzyme 2 http://flybase.org/reports/FBgn0038398 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR033906 cellular_component ; GO:0005575 | no biological data available "CG4979, sxe2" "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG4979 11-Aug-17 DroID_v2017_08 "Drer\lipca, Drer\lipib, Drer\lipia, Drer\lipg, Drer\pla1a, Drer\LOC100331214, Drer\lpl, Drer\LOC101884800" - - "Xtro\lpl, Xtro\lipg" "Mmus\Lipg, Mmus\Lpl, Mmus\Pnliprp1, Mmus\Pnliprp2, Mmus\Pnlip, Mmus\Liph, Mmus\Pla1a, Mmus\Lipc, Mmus\Lipi" "Hsap\PNLIPRP1, Hsap\LIPH, Hsap\PNLIPRP2, Hsap\PNLIPRP3, Hsap\LIPC, Hsap\PLA1A, Hsap\LIPI, Hsap\PNLIP, Hsap\LPL, Hsap\LIPG" viable FBgn0025842 E(var)104 E(var)104 http://flybase.org/reports/FBgn0025842 - gene - - - "E-104, E(var)104" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042142 CG18819 - http://flybase.org/reports/FBgn0042142 protein_coding_gene - - - CG18819 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032409 Ced-12 Ced-12 http://flybase.org/reports/FBgn0032409 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with msk "border follicle cell migration ; GO:0007298 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype activation of GTPase activity ; GO:0090630 | inferred from genetic interaction with Rac1, Rac2, mbc inferred from genetic interaction with Rac1, mbc central nervous system development ; GO:0007417 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from genetic interaction with WB:WBGene00000426 muscle attachment ; GO:0016203 | inferred from mutant phenotype inferred from genetic interaction with mbc inferred from genetic interaction with msk" nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "ELMO, CG5336, Dced-12, Ced-12, ced-12, dced-12, elmo, Ced12, Elmo, dCed-12, ced12, dCed12" "IPR024574:Domain of unknown function DUF3361, IPR016024:Armadillo-type fold, IPR006816:ELMO domain, IPR011993:PH domain-like, IPR011989:Armadillo-like helical, IPR030719:Engulfment and cell motility protein 3, IPR001849:Pleckstrin homology domain" CG5336 11-Aug-17 DroID_v2017_08 "Drer\elmo3, Drer\elmo2, Drer\elmo1, Drer\si:dkey-56f14.7" Scer\LMO1 "Cele\ced-12, Cele\C56G7.3" "Xtro\elmo3, Xtro\elmo1, Xtro\elmo2" "Mmus\Elmo1, Mmus\Elmo2, Mmus\Elmo3" "Hsap\ELMO2, Hsap\ELMO3, Hsap\ELMO1" "lethal,neuroanatomy defective,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "muscle fiber,germline clone,embryonic myoblast,presumptive embryonic/larval muscle system,lateral longitudinal fascicle,border follicle cell,somatic clone,thorax,embryonic myoblast | embryonic stage 16,presumptive embryonic/larval muscle system | embryonic stage 16,reticular neuropil associated glial cell,gamma Kenyon cell,muscle attachment site,tendon cell,muscle fiber | third instar larval stage" FBgn0038916 dnd dead end http://flybase.org/reports/FBgn0038916 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006689, InterPro:IPR024156 GTP binding ; GO:0005525 | inferred from sequence alignment with HGNC:694" "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from sequence model" microtubule cytoskeleton ; GO:0015630 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Arl3, CG6560, dnd, Q9VD64, ARL3, Dnd" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024156:Small GTPase superfamily, ARF type" CG6560 11-Aug-17 DroID_v2017_08 "Drer\arl3, Drer\npm3, Drer\arl3l2, Drer\arl2, Drer\arl13b, Drer\arl3l1, Drer\zgc:110197" Scer\ARF2 "Cele\arl-13, Cele\evl-20, Cele\arl-3" "Xtro\arl2, Xtro\arl3.2, Xtro\arl3.1" "Mmus\Arl3, Mmus\Arl13b, Mmus\Arl2" "Hsap\ARL2, Hsap\ARL3, Hsap\ARL13B" "visible,dominant,wild-type,recessive" "dorsal branch primordium,dorsal trunk primordium" FBgn0028591 l(3)05218 lethal (3) 05218 http://flybase.org/reports/FBgn0028591 gene - - - l(3)05218 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259202 CG42306 - http://flybase.org/reports/FBgn0259202 protein_coding_gene - - - "CG42306, Dromel_CG5469_FBtr0086654_gint3_uORF" - CG42306 11-Aug-17 DroID_v2017_08 Drer\ubxn6 Scer\UBX4 - "Xtro\ubxn6, Xtro\aspscr1" "Mmus\Ubxn6, Mmus\Aspscr1" "Hsap\ASPSCR1, Hsap\UBXN6" FBgn0002535 Lcp4 Larval cuticle protein 4 http://flybase.org/reports/FBgn0002535 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "L[[3]]CP4, LCP-4, 4, IV, LCP4, CG2044, Lcp4, DmelLcp4, lcp4" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2044 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " embryonic stage , pupal stage | 7-13 hr , larval stage , larval stage | third instar stage 2 , larval stage | late third instar larval stage " " integumentary system

, organism

" viable FBgn0013971 Gpr5B G protein-coupled receptor 5B http://flybase.org/reports/FBgn0013971 - gene - - - Gpr5B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028201 l(3)S018801 lethal (3) S018801 http://flybase.org/reports/FBgn0028201 gene - - - "0188/01, l(3)S018801" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0040769 CG12431 - http://flybase.org/reports/FBgn0040769 protein_coding_gene - - - CG12431 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265257 CG44271 - http://flybase.org/reports/FBgn0265257 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44271 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR017907:Zinc finger, RING-type, conserved site" CG44271 11-Aug-17 DroID_v2017_08 "Drer\trim35-29, Drer\trim35-28, Drer\ftr70, Drer\si:ch73-106l15.3, Drer\trim35-7, Drer\trim35-1, Drer\trim35-19, Drer\trim35-24, Drer\trim35-9, Drer\si:ch211-175l6.2, Drer\trim35-20, Drer\trim35-35, Drer\trim35-31, Drer\trim35-13, Drer\si:ch73-166o21.1, Drer\LOC100536643, Drer\si:ch73-106l15.2, Drer\rnf4, Drer\trim35-14, Drer\trim35-10, Drer\trim35-30, Drer\trim35-34, Drer\trim35-3, Drer\trim35-25, Drer\si:ch1073-324l1.1, Drer\trim35-12, Drer\trim35-23, Drer\si:ch211-12p12.2, Drer\trim35-33" - "Cele\C28G1.6, Cele\Y38C1AA.6, Cele\T01G5.7" "Xtro\rnf4, Xtro\trim69.2" "Mmus\Trim7, Mmus\Trim10, Mmus\Rnf4, Mmus\Trim26, Mmus\Trim35" "Hsap\TRIM7, Hsap\RNF4, Hsap\TRIM35, Hsap\TRIM10, Hsap\TRIM26" FBgn0039863 CG1815 - http://flybase.org/reports/FBgn0039863 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 zinc ion binding ; GO:0008270 | inferred from sequence model transcription cofactor activity ; GO:0003712 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000371549" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000371549" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 CG1815 "IPR000313:PWWP domain, IPR001487:Bromodomain, IPR001965:Zinc finger, PHD-type, IPR002893:Zinc finger, MYND-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1815 11-Aug-17 DroID_v2017_08 "Drer\zmynd8, Drer\prkcbp1l" Scer\RCO1 "Cele\bra-1, Cele\bra-2" Xtro\zmynd11 "Mmus\Zmynd8, Mmus\Zmynd11" "Hsap\ZMYND11, Hsap\ZMYND8" viable FBgn0020350 anon-44Aa anon-44Aa http://flybase.org/reports/FBgn0020350 - gene - - - anon-44Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266632 CR45139 - http://flybase.org/reports/FBgn0266632 non_protein_coding_gene - - - CR45139 - CR45139 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260258 GSd321 - http://flybase.org/reports/FBgn0260258 gene - - - GSd321 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040904 CG15577 - http://flybase.org/reports/FBgn0040904 protein_coding_gene - - - CG15577 - CG15577 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001881 l(1)Yi29 lethal (1) Yi29 http://flybase.org/reports/FBgn0001881 - gene - - - l(1)Yi29 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002012 l(2)36Fe lethal (2) 36Fe http://flybase.org/reports/FBgn0002012 - gene - - - "36Fe, Fe, l(2)E134, l(2)36Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025345 anon-17Ab anon-17Ab http://flybase.org/reports/FBgn0025345 - gene - - - anon-17Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044497 DTD45.1 DTD45.1 http://flybase.org/reports/FBgn0044497 gene - - - DTD45.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034907 CG5539 - http://flybase.org/reports/FBgn0034907 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5539 IPR004345:TB2/DP1/HVA22-related protein CG5539 11-Aug-17 DroID_v2017_08 "Drer\reep2, Drer\reep1, Drer\reep3b, Drer\reep3a" Scer\YOP1 "Cele\T19C3.4, Cele\Y110A2AR.1, Cele\W01D2.3, Cele\C06E1.1" "Xtro\reep4, Xtro\reep3" "Mmus\Reep1, Mmus\Reep4, Mmus\Reep2, Mmus\Reep3" "Hsap\REEP3, Hsap\REEP4, Hsap\REEP2, Hsap\REEP1" viable FBgn0266328 CR44993 - http://flybase.org/reports/FBgn0266328 non_protein_coding_gene - - - CR44993 - CR44993 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051272 CG31272 - http://flybase.org/reports/FBgn0051272 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 lipase activity ; GO:0016298 | inferred from sequence or structural similarity transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 lipid metabolic process ; GO:0006629 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 "CG6529, CG31272" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG31272 11-Aug-17 DroID_v2017_08 "Drer\sv2c, Drer\svopa, Drer\sv2, Drer\sv2a, Drer\sv2ba, Drer\svopl, Drer\sv2bb, Drer\svopb" Scer\GAL2 "Cele\oat-1, Cele\svop-1" Xtro\sv2b "Mmus\Sv2a, Mmus\Svopl, Mmus\Sv2b, Mmus\Svop, Mmus\Sv2c" "Hsap\SV2C, Hsap\SVOPL, Hsap\SVOP, Hsap\SV2A, Hsap\SV2B" FBgn0024306 SS3-5 Suppressor of GMR-sina 3-5 http://flybase.org/reports/FBgn0024306 - gene - - - SS3-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053422 5SrRNA:CR33422 5SrRNA:CR33422 http://flybase.org/reports/FBgn0053422 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33422, 5SrRNA:CR33422" - CR33422 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010158 lzl lozengelike http://flybase.org/reports/FBgn0010158 - gene - - - lzl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male fertile,female fertile" eye FBgn0283626 CR46299 - http://flybase.org/reports/FBgn0283626 non_protein_coding_gene - - - "CR46299, CR46222, CR46223, lincRNA.705" - CR46299 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085728 CG42226 - http://flybase.org/reports/FBgn0085728 protein_coding_gene - - - CG42226 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265798 CR44587 - http://flybase.org/reports/FBgn0265798 non_protein_coding_gene - - - "lincRNA.118, CR44587" - CR44587 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004190 snRNA:U6:96Ac small nuclear RNA U6 at 96Ac http://flybase.org/reports/FBgn0004190 "FBgn0003455, FBgn0003939, FBgn0003940, FBgn0051539" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U6 snRNP ; GO:0005688 | inferred from sequence or structural similarity "snRNA:U6:96Ac, CR31539, U6, U6-96Ac, snRNA-b, U6-3, U6snRNA, U6 RNA, DU6-3, snRNA[[4]], K1, dU6, snRNA:U6, snRNA6, snRNA4, U6snRNA96Ac, U6:96Ac, U6 snRNA, U6-snRNA" - CR31539 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086727 Dje5 - http://flybase.org/reports/FBgn0086727 gene - - - "Dje5, Dje 5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031801 CG9498 - http://flybase.org/reports/FBgn0031801 protein_coding_gene - - - CG9498 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG9498 11-Aug-17 DroID_v2017_08 - - "Cele\nhr-246, Cele\Y11D7A.8, Cele\C29F7.2, Cele\C29F7.1" - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC03235 I -0.595652173 1.514980297 0.590529056 0.341236634 -0.312163311 -0.464585315 FBgn0259428 C840 - http://flybase.org/reports/FBgn0259428 gene - - - C840 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0035286 CG13924 - http://flybase.org/reports/FBgn0035286 protein_coding_gene - - - CG13924 IPR026687:Coiled-coil domain-containing protein 181 CG13924 11-Aug-17 DroID_v2017_08 Drer\si:ch211-232d19.4 - - - Mmus\Ccdc181 Hsap\CCDC181 "viable,female fertile" FBgn0035865 CG7201 - http://flybase.org/reports/FBgn0035865 protein_coding_gene - - - CG7201 IPR006631:Protein of unknown function DM4/12 CG7201 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060768 l(3)S062310 lethal (3) S062310 http://flybase.org/reports/FBgn0060768 gene - - - "0623/10, l(3)S062310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031566 CG2818 - http://flybase.org/reports/FBgn0031566 protein_coding_gene starch binding ; GO:2001070 | inferred from electronic annotation with InterPro:IPR002044 glycerophosphocholine phosphodiesterase activity ; GO:0047389 | inferred from biological aspect of ancestor with PANTHER:PTN001120996 glycerophosphodiester phosphodiesterase activity ; GO:0008889 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 glycerophospholipid catabolic process ; GO:0046475 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 cellular phosphate ion homeostasis ; GO:0030643 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 - CG2818 "IPR030395:Glycerophosphodiester phosphodiesterase domain, IPR000909:Phosphatidylinositol-specific phospholipase C, X domain, IPR002044:Carbohydrate binding module family 20, IPR013783:Immunoglobulin-like fold, IPR013784:Carbohydrate-binding-like fold, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR033506:Glycerophosphodiester phosphodiesterase Gde1" CG2818 11-Aug-17 DroID_v2017_08 Drer\gpcpd1 "Scer\PHO81, Scer\GDE1" "Cele\gpcp-1, Cele\gpcp-2" Xtro\gpcpd1 Mmus\Gpcpd1 Hsap\GPCPD1 viable FBgn0025125 su(RpII140[Z36])S3 su(RpII140[Z36])S3 http://flybase.org/reports/FBgn0025125 - gene - - - "Z36[S3], su(RpII140[Z36])S3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022259 l(2)k00808 lethal (2) k00808 http://flybase.net/reports/FBgn0022259.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0033725 Cpr49Ac Cuticular protein 49Ac http://flybase.org/reports/FBgn0033725 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 hemolymph coagulation ; GO:0042381 | inferred from expression pattern chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model extracellular region ; GO:0005576 | inferred from direct assay "Cpr49Ac, CG8502" IPR000618:Insect cuticle protein CG8502 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\F44F1.4, Cele\math-34" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0259733 tal-AA tarsal-less AA http://flybase.org/reports/FBgn0259733 protein_coding_gene molecular_function ; GO:0003674 | no biological data available actin filament organization ; GO:0007015 | inferred from genetic interaction with tal morphogenesis of an epithelium ; GO:0002009 | inferred from genetic interaction with tal cellular_component ; GO:0005575 | no biological data available "Dm4, tal-AA, CG42387, Pep4, ORF4, tal, ORF AA, pri, Dm_3R:52381" - CG42387 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024659 l(2)k07403 lethal (2) k07403 http://flybase.org/reports/FBgn0024659 - gene - - - "74/3, l(2)k07403" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,anterior compartment" FBgn0037923 CG6813 - http://flybase.org/reports/FBgn0037923 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG31372, CG6813" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG6813 11-Aug-17 DroID_v2017_08 "Drer\LOC103911751, Drer\si:ch211-241b2.4" - "Cele\blmp-1, Cele\M03D4.4, Cele\klf-3, Cele\ztf-23" - "Mmus\Zfp110, Mmus\Zscan5b, Mmus\Zfp445, Mmus\Zfp24, Mmus\Rbak, Mmus\Zfp369" "Hsap\ZSCAN22, Hsap\ZFP69B, Hsap\ZNF3, Hsap\ZNF302, Hsap\ZNF684, Hsap\ZNF10, Hsap\ZNF19, Hsap\ZNF557, Hsap\ZNF844, Hsap\ZNF560, Hsap\ZNF396, Hsap\ZSCAN20, Hsap\ZNF202, Hsap\ZNF806, Hsap\ZNF554, Hsap\ZNF18, Hsap\ZKSCAN4, Hsap\ZNF383, Hsap\ZNF263, Hsap\ZNF514, Hsap\ZNF547, Hsap\ZNF101, Hsap\ZKSCAN7, Hsap\ZNF205, Hsap\ZNF197, Hsap\ZNF232, Hsap\ZNF460, Hsap\ZNF621, Hsap\MZF1, Hsap\ZNF701, Hsap\ZNF75D, Hsap\ZNF577, Hsap\ZNF483, Hsap\ZNF213, Hsap\ZNF620, Hsap\ZNF506, Hsap\ZKSCAN3, Hsap\ZNF641, Hsap\ZNF829, Hsap\ZIM3, Hsap\ZNF8, Hsap\ZNF285, Hsap\ZNF500, Hsap\ZNF154, Hsap\ZSCAN16, Hsap\ZNF354C, Hsap\ZSCAN23, Hsap\ZNF773, Hsap\ZNF286A, Hsap\ZNF169, Hsap\ZNF649, Hsap\ZNF550, Hsap\ZNF2, Hsap\ZSCAN12, Hsap\ZNF485, Hsap\ZKSCAN1, Hsap\ZNF496, Hsap\ZNF584, Hsap\ZNF565, Hsap\ZSCAN25, Hsap\ZSCAN31, Hsap\ZNF562, Hsap\ZSCAN26, Hsap\ZNF397, Hsap\ZNF735, Hsap\ZNF350, Hsap\ZSCAN10, Hsap\ZNF124, Hsap\ZNF449, Hsap\ZNF662, Hsap\ZNF517, Hsap\ZSCAN1, Hsap\ZNF274, Hsap\ZFP69, Hsap\ZNF582, Hsap\ZNF24, Hsap\ZKSCAN5, Hsap\ZNF444, Hsap\ZNF574, Hsap\ZSCAN21, Hsap\GZF1, Hsap\ZNF736, Hsap\ZFP92, Hsap\ZNF566, Hsap\ZNF789, Hsap\ZSCAN30, Hsap\ZKSCAN8, Hsap\ZNF140, Hsap\ZNF669" "viable,fertile" FBgn0053533 lectin-37Db lectin-37Db http://flybase.org/reports/FBgn0053533 protein_coding_gene galactose binding ; GO:0005534 | inferred from direct assay galactose binding ; GO:0005534 | inferred from sequence or structural similarity calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model inferred from direct assay "AC007082c, AC 007082C, CG9978, CG33533, lectin-37Db, DL3" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG33533 11-Aug-17 DroID_v2017_08 "Drer\colec11, Drer\si:dkey-83f18.10, Drer\si:ch211-283g2.3, Drer\selp, Drer\si:ch73-361h17.1" - "Cele\clec-178, Cele\F52E1.2, Cele\clec-149" "Xtro\clec10a, Xtro\clec4e, Xtro\colec10" "Mmus\Clec4a4, Mmus\Clec4a3, Mmus\Clec4d, Mmus\Clec4a2, Mmus\Clec4n, Mmus\Sell, Mmus\Clec4b1, Mmus\Asgr2, Mmus\Clec4a1, Mmus\Clec4b2, Mmus\Cd209d, Mmus\Colec10" "Hsap\COLEC10, Hsap\CLEC3A, Hsap\CLEC11A, Hsap\ASGR2" FBgn0261734 EC2388 - http://flybase.org/reports/FBgn0261734 gene - - - EC2388 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0260776 CG42570 - http://flybase.org/reports/FBgn0260776 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42570, new ORF" IPR020846:Major facilitator superfamily domain CG42570 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010664 l(2)10505 lethal (2) 10505 http://flybase.net/reports/FBgn0010664.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0005674 GluProRS Glutamyl-prolyl-tRNA synthetase http://flybase.org/reports/FBgn0005674 FBgn0027089 protein_coding_gene "glutamate-tRNA ligase activity ; GO:0004818 | inferred from electronic annotation with InterPro:IPR004526 proline-tRNA ligase activity ; GO:0004827 | inferred from electronic annotation with InterPro:IPR004499, InterPro:IPR016061, InterPro:IPR017449 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000738, InterPro:IPR000924, InterPro:IPR001412, InterPro:IPR002314, InterPro:IPR004499, InterPro:IPR004526, InterPro:IPR016061, InterPro:IPR017449, InterPro:IPR020058, InterPro:IPR020059, InterPro:IPR020061 proline-tRNA ligase activity ; GO:0004827 | traceable author statement glutamate-tRNA ligase activity ; GO:0004818 | traceable author statement" "glutamyl-tRNA aminoacylation ; GO:0006424 | inferred from electronic annotation with InterPro:IPR004526 prolyl-tRNA aminoacylation ; GO:0006433 | inferred from electronic annotation with InterPro:IPR004499, InterPro:IPR016061, InterPro:IPR017449 glutamyl-tRNA aminoacylation ; GO:0006424 | traceable author statement prolyl-tRNA aminoacylation ; GO:0006433 | traceable author statement" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000924, InterPro:IPR004499, InterPro:IPR004526, InterPro:IPR016061, InterPro:IPR017449, InterPro:IPR020059, InterPro:IPR020061 aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement" "CG5394, EPRS, p200, AATS, AATs-GluPro, GluProRS, glutamyl-prolyl-tRNA synthetase, GluRS, ERS, GluPro-RS, Aats-glu, Aa-tRNA-syn-glupro, Aats-glupro, Glu-ProRS, FBpp0083898" "IPR000738:WHEP-TRS domain, IPR000924:Glutamyl/glutaminyl-tRNA synthetase, IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002314:Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR004154:Anticodon-binding, IPR004499:Proline-tRNA ligase, class IIa, archaeal-type, IPR004526:Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR009068:S15/NS1, RNA-binding, IPR010987:Glutathione S-transferase, C-terminal-like, IPR011035:Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR016061:Proline-tRNA ligase, class II, C-terminal, IPR017449:Prolyl-tRNA synthetase, class II, IPR020058:Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain, IPR020059:Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain, IPR020061:Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain, IPR020056:Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain, IPR004046:Glutathione S-transferase, C-terminal, IPR033721:Prolyl-tRNA synthetase, catalytic domain" CG5394 11-Aug-17 DroID_v2017_08 "Drer\eprs, Drer\rprd2b" "Scer\YHR020W, Scer\GUS1" "Cele\pars-1, Cele\ears-1" Xtro\eprs Mmus\Eprs Hsap\EPRS embryonic stage

ubiquitous "female fertile,reduced,lethal" DRSC14095 K -0.578235006 0.346191897 -0.186586759 0.265234653 -1.179654268 1.530766105 FBgn0031042 CG14221 - http://flybase.org/reports/FBgn0031042 protein_coding_gene - "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017937" - CG14221 "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site, IPR031827:Domain of unknown function DUF4746" CG14221 11-Aug-17 DroID_v2017_08 Drer\nme8 - - - "Mmus\Nme8, Mmus\Nme9" Hsap\NME9 viable FBgn0024689 fws four way stop http://flybase.org/reports/FBgn0024689 "FBgn0027736, FBgn0027744, FBgn0032641" protein_coding_gene molecular_function ; GO:0003674 | no biological data available meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000325596 spermatid nucleus elongation ; GO:0007290 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000004996 acrosome assembly ; GO:0001675 | inferred from mutant phenotype membrane organization ; GO:0061024 | non-traceable author statement Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi transport complex ; GO:0017119 | inferred from direct assay "fws, dCOG5, CG6549, anon-EST:Posey186, anon-EST:Posey162, COG5, FWS, Cog5, Fws" IPR019465:Conserved oligomeric Golgi complex subunit 5 CG6549 11-Aug-17 DroID_v2017_08 "Drer\cdk10, Drer\cog5, Drer\cdk11b" Scer\COG5 "Cele\cdk-11.2, Cele\cogc-5, Cele\K09F6.4, Cele\cdk-11.1" "Xtro\cdk10, Xtro\cdk11b" "Mmus\Cdk11b, Mmus\Cdk10, Mmus\Cog5" "Hsap\CDK10, Hsap\COG5, Hsap\CDK11A, Hsap\CDK11B" "meiotic cell cycle defective,male,cytokinesis defective,mitotic cell cycle defective,recessive,viable" "spermatid & nucleus | supernumeraryqua1374),Nebenkern,spindle & meiotic telophase I | malequa1374),contractile ring & meiotic telophase I | malequa1374),spindle & meiotic telophase II | malequa1374),contractile ring & meiotic telophase II | malequa1374),spermatid & nucleus | supernumerary,spindle & meiotic telophase I | male,contractile ring & meiotic telophase I | male,spindle & meiotic telophase II | male,contractile ring & meiotic telophase II | male" DRSC29678 IK 1.507880744 -0.176093941 0.248858866 0.204749529 1.235833111 1.890138981 FBgn0031321 Tgt tRNA-guanine transglycosylase http://flybase.org/reports/FBgn0031321 protein_coding_gene queuine tRNA-ribosyltransferase activity ; GO:0008479 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q9JMA2 tRNA modification ; GO:0006400 | inferred from electronic annotation with InterPro:IPR002616 queuosine biosynthetic process ; GO:0008616 | inferred from sequence or structural similarity with UniProtKB:Q9JMA2 - "CG4947, TGT, Tgt, tgt" "IPR002616:tRNA-guanine(15) transglycosylase-like, IPR004803:tRNA-guanine transglycosylase" CG4947 11-Aug-17 DroID_v2017_08 Drer\qtrt1 - Cele\tgt-1 Xtro\qtrt1 Mmus\Qtrt1 Hsap\QTRT1 viable FBgn0038388 CG4287 - http://flybase.org/reports/FBgn0038388 protein_coding_gene - - - CG4287 - CG4287 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,wild-type,lethal - all die before end of larval stage,some die during larval stage" larva FBgn0013614 l(3)L1159 lethal (3) L1159 http://flybase.org/reports/FBgn0013614 - gene - - - l(3)L1159 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029968 Ir7g Ionotropic receptor 7g http://flybase.org/reports/FBgn0029968 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir7g, DmelIR7g, CG15325, IR7g" - CG15325 11-Aug-17 DroID_v2017_08 "Drer\grik4, Drer\grik1b, Drer\si:ch211-251b21.1, Drer\si:dkey-183j2.10, Drer\grik1a" - "Cele\glr-8, Cele\glr-5, Cele\glr-4" - "Mmus\Grik4, Mmus\Grik1" "Hsap\GRIK4, Hsap\GRIN2C, Hsap\GRIK3, Hsap\GRIK1, Hsap\GRID1" viable FBgn0033140 CG12836 - http://flybase.org/reports/FBgn0033140 protein_coding_gene - - - "CG12836, mdcds_19139" IPR005334:Tctex-1 CG12836 11-Aug-17 DroID_v2017_08 "Drer\tctex1d2, Drer\tctex1d1" - Cele\dylt-2 Xtro\tctex1d1 "Mmus\Tcte3, Mmus\Tctex1d2, Mmus\Tctex1d4, Mmus\Gm3448, Mmus\Gm3417, Mmus\Tctex1d1" "Hsap\TCTE3, Hsap\TCTEX1D1, Hsap\TCTEX1D4, Hsap\TCTEX1D2" viable FBgn0265636 CR44443 - http://flybase.org/reports/FBgn0265636 non_protein_coding_gene - - - "CR44443, lincRNA.259" - CR44443 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053411 5SrRNA:CR33411 5SrRNA:CR33411 http://flybase.org/reports/FBgn0053411 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33411, 5SrRNA:CR33411" - CR33411 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033005 CG3107 - http://flybase.org/reports/FBgn0033005 protein_coding_gene "metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011237, InterPro:IPR011249 metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity with UniProtKB:Q5JRX3" proteolysis ; GO:0006508 | inferred from sequence or structural similarity with UniProtKB:Q5JRX3 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q5JRX3 CG3107 "IPR007863:Peptidase M16, C-terminal, IPR013578:Peptidase M16C associated, IPR011249:Metalloenzyme, LuxS/M16 peptidase-like, IPR011765:Peptidase M16, N-terminal" CG3107 11-Aug-17 DroID_v2017_08 Drer\pitrm1 "Scer\AXL1, Scer\CYM1, Scer\SDD3" Cele\C05D11.1 Xtro\pitrm1 Mmus\Pitrm1 Hsap\PITRM1 viable FBgn0285896 btl breathless http://flybase.org/reports/FBgn0285896 protein_coding_gene "fibroblast growth factor-activated receptor activity ; GO:0005007 | inferred from sequence or structural similarity fibroblast growth factor-activated receptor activity ; GO:0005007 | inferred from sequence or structural similarity with MGD:Fgfr1; MGI:MGI:95522 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement fibroblast growth factor-activated receptor activity ; GO:0005007 | traceable author statement ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441" "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from expression pattern glial cell migration ; GO:0008347 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | inferred from mutant phenotype secondary branching, open tracheal system ; GO:0007429 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement open tracheal system development ; GO:0007424 | non-traceable author statement terminal branching, open tracheal system ; GO:0007430 | traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement open tracheal system development ; GO:0007424 | traceable author statement morphogenesis of a branching structure ; GO:0001763 | traceable author statement salivary gland morphogenesis ; GO:0007435 | non-traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | non-traceable author statement genital disc development ; GO:0035215 | inferred from expression pattern filopodium assembly ; GO:0046847 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | traceable author statement secondary branching, open tracheal system ; GO:0007429 | traceable author statement epithelial cell type specification, open tracheal system ; GO:0035153 | inferred from mutant phenotype negative regulation of axon extension ; GO:0030517 | inferred from mutant phenotype activation of MAPK activity ; GO:0000187 | inferred from expression pattern border follicle cell migration ; GO:0007298 | inferred from mutant phenotype branching involved in open tracheal system development ; GO:0060446 | inferred from mutant phenotype trachea development ; GO:0060438 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred by curator from GO:0005007 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC_gene:FGFR1; HGNC:3688; OMIM:136350 plasma membrane ; GO:0005886 | inferred from direct assay cytoneme ; GO:0035230 | colocalizes_with inferred from direct assay "btl, dev, FGFR, D-FGFR, DFR2, CT20816, CG6714, BTL/FGFR2, dtk2, DFGF-R1, DmHD-311, Dfr-2, 0844/01, Btl, FGFR1, Fgf-r, fgf-r, dFGFR, l(3)00208, Tk2, HD-311, Dtk2, CG32134, lambdatop, l(3)j2E11" "IPR000719:Protein kinase domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013783:Immunoglobulin-like fold, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR013098:Immunoglobulin I-set, IPR013151:Immunoglobulin" CG32134 11-Aug-17 DroID_v2017_08 "Drer\tek, Drer\fgfrl1a, Drer\tada2b, Drer\styk1, Drer\fgfr2, Drer\pdgfra, Drer\fgfr4, Drer\tie1, Drer\fgfr1b, Drer\si:dkey-14o18.6, Drer\kdr, Drer\kdrl, Drer\ret, Drer\kita, Drer\pdgfrl, Drer\flt3, Drer\flt4, Drer\kitb, Drer\csf1ra, Drer\si:ch73-206d17.1, Drer\fgfr3, Drer\si:ch211-167j9.5, Drer\fgfr1a, Drer\csf1rb, Drer\fgfrl1b, Drer\pdgfrb, Drer\flt1, Drer\LOC569566" Scer\SKM1 "Cele\R151.1, Cele\F09A5.2, Cele\egl-15, Cele\C24G6.2, Cele\F09G2.1, Cele\svh-2, Cele\kin-9" "Xtro\pdgfra, Xtro\pdgfrl, Xtro\fgfr1, Xtro\kdr, Xtro\fgfr4, Xtro\tada2b, Xtro\fgfrl1, Xtro\ret, Xtro\pdgfrl.2, Xtro\flt4, Xtro\flt1, Xtro\styk1, Xtro\fgfr2, Xtro\csf1r, Xtro\fgfr3, Xtro\tek, Xtro\tie1" "Mmus\Fgfr2, Mmus\Flt4, Mmus\Fgfr1, Mmus\Kit, Mmus\Tada2b, Mmus\Fgfrl1, Mmus\Csf1r, Mmus\Fgfr3, Mmus\Flt3, Mmus\Flt1, Mmus\Styk1, Mmus\Tie1, Mmus\Ret, Mmus\Pdgfra, Mmus\Tek, Mmus\Pdgfrb, Mmus\Fgfr4, Mmus\Pdgfrl, Mmus\Kdr" "Hsap\FLT4, Hsap\FLT1, Hsap\FLT3, Hsap\KIT, Hsap\TADA2B, Hsap\RET, Hsap\FGFR4, Hsap\FGFRL1, Hsap\FGFR2, Hsap\FGFR1, Hsap\PDGFRB, Hsap\KDR, Hsap\STYK1, Hsap\TEK, Hsap\PDGFRA, Hsap\TIE1, Hsap\FGFR3, Hsap\PDGFRL, Hsap\CSF1R" "lethal,recessive" FBgn0022539 Gld::Dpse\Gld Gld::Dpse\Gld http://flybase.org/reports/FBgn0022539 - engineered_fusion_gene - - - Gld::Dpse\Gld - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011489 l(3)neo59 lethal (3) neo59 http://flybase.org/reports/FBgn0011489 - gene - - - l(3)neo59 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0250867 CG42238 - http://flybase.org/reports/FBgn0250867 protein_coding_gene - - - "CG42238, CG9266" - CG42238 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259362 C389 - http://flybase.org/reports/FBgn0259362 gene - - - C389 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,chaeta" FBgn0000692 flrdP flight reduced P http://flybase.org/reports/FBgn0000692 - gene - - - flrdP - - 11-Aug-17 DroID_v2017_08 - - - - - - "jumping defective,bang sensitive,uncoordinated,conditional,flight defective" FBgn0016067 slbo::Rat\C-EBP-alpha C-EBP-alpha http://flybase.org/reports/FBgn0016067 - engineered_fusion_gene - - - "slbo::Rat\C/EBP-alpha, slbo::Rat\C-EBP-alpha" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023541 Cyp4d14 Cyp4d14 http://flybase.org/reports/FBgn0023541 FBgn0029602 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4d14, EG:152A3.2, CG3540, CYP4D14, Cyp4d14" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG3540 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp4v8, Drer\cyp46a1.3, Drer\cyp4v7, Drer\cyp46a1.1, Drer\cyp4f3, Drer\LOC100329425, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp3c2, Drer\cyp3c4, Drer\cyp4t8, Drer\cyp19a1b, Drer\cyp26a1, Drer\cyp19a1a, Drer\cyp26b1, Drer\cyp20a1, Drer\cyp46a1.2, Drer\cyp46a1.4, Drer\cyp26c1" "Scer\ERG5, Scer\DIT2" "Cele\cyp-32A1, Cele\cyp-25A2, Cele\cyp-13A8, Cele\cyp-25A1, Cele\cyp-29A3, Cele\cyp-29A2, Cele\cyp-25A3, Cele\cyp-13A7, Cele\cyp-13A3, Cele\cyp-13A1, Cele\cyp-42A1, Cele\cyp-37A1, Cele\cyp-13A10, Cele\cyp-31A3, Cele\cyp-31A2, Cele\cyp-13A11, Cele\cyp-25A4, Cele\cyp-13A12, Cele\cyp-13A4, Cele\cyp-31A5, Cele\cyp-13A5, Cele\cyp-29A4, Cele\cyp-32B1, Cele\cyp-37B1" "Xtro\cyp20a1, Xtro\cyp4v2, Xtro\cyp26a1, Xtro\cyp4b1, Xtro\cyp4f22, Xtro\cyp26c1, Xtro\cyp19a1, Xtro\mgc108213, Xtro\LOC100487918, Xtro\LOC100488227, Xtro\cyp4f2, Xtro\cyp26b1, Xtro\cyp4b1.2" "Mmus\Cyp3a44, Mmus\Cyp26a1, Mmus\Cyp3a13, Mmus\Cyp3a11, Mmus\Cyp46a1, Mmus\Cyp26b1, Mmus\Cyp26c1, Mmus\Cyp4a31, Mmus\Cyp3a59, Mmus\Cyp4v3, Mmus\Cyp19a1, Mmus\Cyp4a12a, Mmus\Cyp4a14, Mmus\Cyp4f37, Mmus\Cyp4f13, Mmus\Cyp4f18, Mmus\Cyp4a10, Mmus\Cyp3a41b, Mmus\Cyp4a12b, Mmus\Cyp4f17, Mmus\Cyp4f16, Mmus\Cyp3a16, Mmus\Cyp20a1, Mmus\Cyp4f15, Mmus\Cyp4f40, Mmus\Cyp4x1, Mmus\Cyp4a32, Mmus\Cyp4b1, Mmus\Cyp3a25, Mmus\Cyp4a30b, Mmus\Cyp3a41a, Mmus\Cyp3a57, Mmus\Cyp4a29, Mmus\Cyp4f14, Mmus\Cyp4f39" "Hsap\CYP4V2, Hsap\CYP4F12, Hsap\CYP4Z1, Hsap\CYP4A11, Hsap\CYP3A4, Hsap\CYP26C1, Hsap\CYP26A1, Hsap\CYP4F3, Hsap\CYP4B1, Hsap\CYP26B1, Hsap\CYP3A5, Hsap\CYP20A1, Hsap\CYP4A22, Hsap\CYP4F8, Hsap\CYP3A43, Hsap\CYP46A1, Hsap\CYP4F11, Hsap\CYP19A1, Hsap\CYP4F22, Hsap\CYP3A7, Hsap\CYP4X1, Hsap\CYP4F2" viable FBgn0024533 l(3)L1022 lethal (3) L1022 http://flybase.org/reports/FBgn0024533 - gene - - - "LD11808, EP(3)3334, l(3)L1022" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083284 E(smoDN)2162 Enhancer of smoDN 2162 http://flybase.org/reports/FBgn0083284 gene - - - E(smoDN)2162 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051926 CG31926 - http://flybase.org/reports/FBgn0051926 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 eggshell chorion assembly ; GO:0007306 | inferred from expression pattern inferred from genomic context protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 chorion ; GO:0042600 | inferred from genomic context "CG10872, CG31926" "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG31926 11-Aug-17 DroID_v2017_08 "Drer\ren, Drer\zgc:103530, Drer\ctsd, Drer\zgc:63831, Drer\nots" "Scer\YPS5, Scer\YPS3, Scer\YPS7, Scer\BAR1, Scer\YPS1, Scer\YGL258W-A, Scer\PEP4, Scer\YPS6, Scer\MKC7" "Cele\asp-10, Cele\asp-17, Cele\asp-3, Cele\asp-1, Cele\asp-16, Cele\asp-8, Cele\asp-4, Cele\asp-14, Cele\asp-15, Cele\asp-5, Cele\asp-13, Cele\asp-6, Cele\asp-7, Cele\asp-19, Cele\asp-2, Cele\asp-12, Cele\asp-9, Cele\asp-18" "Xtro\pgc, Xtro\napsa, Xtro\pga4, Xtro\LOC496913, Xtro\ctsd, Xtro\bace2, Xtro\ctse, Xtro\bace1, Xtro\ren" "Mmus\Ctse, Mmus\Ren2, Mmus\Napsa, Mmus\Pga5, Mmus\Ren1, Mmus\Bace1, Mmus\Pgc, Mmus\Ctsd, Mmus\Cym, Mmus\Bace2" "Hsap\PGC, Hsap\REN, Hsap\NAPSA, Hsap\PGA5, Hsap\CTSE, Hsap\BACE1, Hsap\CTSD, Hsap\BACE2, Hsap\PGA4, Hsap\PGA3" FBgn0065547 l(2)SH1046 lethal (2) SH1046 http://flybase.org/reports/FBgn0065547 gene - - - "l(2)SH1046, l(2)SH2 1046" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033761 CG8778 - http://flybase.org/reports/FBgn0033761 protein_coding_gene enoyl-CoA hydratase activity ; GO:0004300 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 cold acclimation ; GO:0009631 | inferred from expression pattern mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000941570 microtubule associated complex ; GO:0005875 | inferred from direct assay CG8778 "IPR001753:Crotonase superfamily, IPR018376:Enoyl-CoA hydratase/isomerase, conserved site, IPR029045:ClpP/crotonase-like domain, IPR014748:Crontonase, C-terminal" CG8778 11-Aug-17 DroID_v2017_08 "Drer\auh, Drer\spcs3, Drer\echdc2" "Scer\DCI1, Scer\ECI1" "Cele\K12H4.4, Cele\C32E8.9, Cele\ech-5" "Xtro\auh, Xtro\echdc2, Xtro\spcs3" "Mmus\Arxes2, Mmus\Echdc2, Mmus\Auh, Mmus\Spcs3, Mmus\Arxes1" "Hsap\SPCS3, Hsap\ECHDC2, Hsap\AUH" "viable,fertile" FBgn0001028 Fs(3)Ava Female sterile (3) Avar http://flybase.org/reports/FBgn0001028 - gene molecular_function ; GO:0003674 | no biological data available oviposition ; GO:0018991 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Fs(3)Avar, Fs(3)Sz2, Fs(3)Ava" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,dominant,maternal effect,some die during embryonic stage" "ovary,maternal effect" FBgn0261375 Dox-3 Dopa oxidase-3 http://flybase.org/reports/FBgn0261375 gene - - - "Dox-3, Dox, Dox3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "electrophoretic variant,fast,slow,viable" FBgn0024921 Trn Transportin http://flybase.org/reports/FBgn0024921 - protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nuclear localization sequence binding ; GO:0008139 | inferred from sequence or structural similarity with SGD:S000000221 "protein import into nucleus ; GO:0006606 | inferred from sequence or structural similarity with SGD:S000000221 neurogenesis ; GO:0022008 | inferred from mutant phenotype protein import into nucleus, translocation ; GO:0000060 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 ribosomal protein import into nucleus ; GO:0006610 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype regulation of protein import into nucleus ; GO:0042306 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 phagocytosis ; GO:0006909 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nuclear periphery ; GO:0034399 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 cytosol ; GO:0005829 | inferred from sequence or structural similarity with SGD:S000000221 nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "dTRN, Trn1, CG7398, Tm, TRN, Trn, IMPbeta2, dTNPO, dTrn" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG7398 11-Aug-17 DroID_v2017_08 "Drer\tnpo1, Drer\LOC100005536, Drer\tnpo2" Scer\KAP104 Cele\imb-2 "Xtro\tnpo2, Xtro\tnpo1" "Mmus\Tnpo2, Mmus\Tnpo1" "Hsap\TNPO1, Hsap\TNPO2" "lethal,neuroanatomy defective,partially lethal - majority die,visible,female sterile,viable" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,embryonic/larval brain" DRSC11309 EK -0.891989817 -0.119561299 -0.96755615 -2.849460769 1.294085931 1.766691323 FBgn0027650 l(2)50B lethal (2) 50B http://flybase.org/reports/FBgn0027650 - gene - - - l(2)50B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037626 CG8236 - http://flybase.org/reports/FBgn0037626 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8236 - CG8236 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0261477 slim scruin like at the midline http://flybase.org/reports/FBgn0261477 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of stress-activated MAPK cascade ; GO:0032874 | inferred from direct assay Cul2-RING ubiquitin ligase complex ; GO:0031462 | inferred from direct assay "CG5186, slim, l(2)s1866" "IPR015915:Kelch-type beta propeller, IPR006652:Kelch repeat type 1, IPR015916:Galactose oxidase, beta-propeller" CG5186 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001301, Drer\klhdc10, Drer\zgc:163014, Drer\krcp, Drer\rabepk, Drer\si:dkey-3d4.3, Drer\klhdc3" "Scer\KEL2, Scer\KEL3, Scer\KEL1" Cele\Y67H2A.2 "Xtro\fbxo42, Xtro\klhdc9, Xtro\klhdc1, Xtro\rabepk, Xtro\klhdc2, Xtro\klhdc10" "Mmus\Klhdc10, Mmus\Klhdc2, Mmus\Fbxo42, Mmus\Klhdc1, Mmus\Klhdc9, Mmus\Rabepk, Mmus\Klhdc3" "Hsap\KLHDC10, Hsap\KLHDC1, Hsap\KLHDC3, Hsap\RABEPK, Hsap\KLHDC2, Hsap\FBXO42, Hsap\KLHDC9" FBgn0266134 c189 - http://flybase.org/reports/FBgn0266134 gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - c189 - - 11-Aug-17 DroID_v2017_08 - - - - - - gravitaxis defective FBgn0032126 CG13113 - http://flybase.org/reports/FBgn0032126 protein_coding_gene - eggshell chorion assembly ; GO:0007306 | inferred from expression pattern inferred from genomic context chorion ; GO:0042600 | inferred from genomic context CG13113 - CG13113 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003646 Su(z)4 Suppressor of zeste 4 http://flybase.org/reports/FBgn0003646 - gene - - - Su(z)4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" pigment cell FBgn0033748 vis vismay http://flybase.org/reports/FBgn0033748 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR008422, InterPro:IPR009057 protein binding ; GO:0005515 | inferred from physical interaction with Mad inferred from physical interaction with Smox transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" "spermatogenesis ; GO:0007283 | inferred from expression pattern inferred from mutant phenotype inferred from physical interaction with aly inferred from physical interaction with comr positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay spermatogenesis ; GO:0007283 | inferred from expression pattern inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "zaa, CG8821, vis, achi/vis, TGIFa, dTGIFa" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR008422:Homeobox KN domain" CG8821 11-Aug-17 DroID_v2017_08 "Drer\irx6a, Drer\irx4b, Drer\meis1b, Drer\meis2b, Drer\irx1b, Drer\pknox2, Drer\tgif1, Drer\pknox1.2, Drer\meis2a, Drer\meis1a, Drer\irx2a, Drer\irx5a, Drer\irx3a, Drer\irx3b, Drer\irx1a, Drer\mkxa, Drer\pknox1.1, Drer\meis3, Drer\irx4a, Drer\irx5b, Drer\irx7" "Scer\TOS8, Scer\HMRA2, Scer\CUP9, Scer\MATALPHA2, Scer\HMLALPHA2" "Cele\unc-62, Cele\psa-3" "Xtro\meis1, Xtro\meis2, Xtro\irx1, Xtro\mkx, Xtro\irx5, Xtro\irx3, Xtro\meis3, Xtro\tgif1, Xtro\pknox2, Xtro\tgif2, Xtro\irx4, Xtro\irx2" "Mmus\Pknox1, Mmus\Irx2, Mmus\Meis2, Mmus\Irx4, Mmus\Irx6, Mmus\Meis3, Mmus\Irx1, Mmus\Irx3, Mmus\Tgif2lx1, Mmus\Meis1, Mmus\Tgif2, Mmus\Tgif1, Mmus\Tgif2lx2, Mmus\Pknox2, Mmus\Mkx, Mmus\Irx5" "Hsap\IRX5, Hsap\PKNOX2, Hsap\MEIS2, Hsap\MEIS1, Hsap\TGIF2, Hsap\TGIF2LX, Hsap\TGIF2LY, Hsap\IRX1, Hsap\IRX4, Hsap\IRX6, Hsap\IRX3, Hsap\TGIF1, Hsap\IRX2, Hsap\MKX, Hsap\TGIF2-C20orf24, Hsap\PKNOX1" " adult stage , embryonic stage -- adult stage " " organism

, testis | restricted

, testis

" " embryonic stage , adult stage , adult stage | male , larval stage " " organism

, egg chamber

, spermatid

, spermatocyte

, testis

, dorsal mesothoracic disc

, ovary

" "viable,visible" "trichogen cell,supernumerary" FBgn0038903 RpI12 RpI12 http://flybase.org/reports/FBgn0038903 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR012164 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001222" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR012164 mRNA cleavage ; GO:0006379 | inferred from electronic annotation with InterPro:IPR034004" - "CG13418, RpI12" "IPR001222:Zinc finger, TFIIS-type, IPR012164:DNA-directed RNA polymerase subunit/transcription factor S, IPR034004:Pol I subunit A12, C-terminal zinc ribbon, IPR019761:DNA-directed RNA polymerase M, 15kDa subunit, conserved site" CG13418 11-Aug-17 DroID_v2017_08 Drer\znrd1 Scer\RPA12 Cele\rpoa-12 Xtro\znrd1 Mmus\Znrd1 Hsap\ZNRD1 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0065260 l(2)SH2088 lethal (2) SH2088 http://flybase.org/reports/FBgn0065260 gene - - - "l(2)SH2088, l(2)SH2 2088" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262982 CG43290 - http://flybase.org/reports/FBgn0262982 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43290 - CG43290 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262990 CR43298 - http://flybase.org/reports/FBgn0262990 non_protein_coding_gene - - - "CR43298, lincRNA.943" - CR43298 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029894 CG14440 - http://flybase.org/reports/FBgn0029894 protein_coding_gene - - - CG14440 - CG14440 11-Aug-17 DroID_v2017_08 Drer\znf821 - Cele\C05D11.13 Xtro\znf821 Mmus\Zfp821 Hsap\ZNF821 viable FBgn0265639 CR44446 - http://flybase.org/reports/FBgn0265639 non_protein_coding_gene - - - "CR44446, lincRNA.264" - CR44446 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004589 Eig71Eb Ecdysone-induced gene 71Eb http://flybase.org/reports/FBgn0004589 - protein_coding_gene - defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 extracellular region ; GO:0005576 | inferred from sequence model "L71, CG7355, L71-2, II, gene II, gene-II, Eig71Eb" IPR003475:Insect protein of unknown function CG7355 11-Aug-17 DroID_v2017_08 - - Cele\W08F4.10 - - - DRSC11149 K 0.654948817 0.327867619 -0.038734697 0.218238894 -0.323373148 -1.567154995 FBgn0065553 l(2)SH1024 lethal (2) SH1024 http://flybase.org/reports/FBgn0065553 gene - - - "l(2)SH1024, l(2)SH2 1024" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040366 CG11398 - http://flybase.org/reports/FBgn0040366 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - "EG:BACR42I17.11, CG11398" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG11398 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-40a17.4, Drer\si:ch211-276c2.4, Drer\si:ch211-198a12.6, Drer\zgc:165514, Drer\zgc:171673, Drer\si:ch211-222k6.2, Drer\si:dkey-261j4.5, Drer\LOC100330167, Drer\si:ch73-299h12.9, Drer\LOC799968, Drer\LOC100538142, Drer\si:dkey-261j4.3, Drer\LOC103911016, Drer\si:dkey-34m19.3, Drer\LOC101883594, Drer\LOC101883230, Drer\LOC100537317, Drer\drl, Drer\im:7141269, Drer\LOC100333031, Drer\si:ch211-241b2.4, Drer\zgc:112998, Drer\LOC103909987, Drer\si:dkey-261j4.4, Drer\LOC108179164, Drer\si:dkey-262g12.3, Drer\zbtb24, Drer\znf366, Drer\wu:fe17e08, Drer\LOC560148, Drer\si:ch211-155e24.3" Scer\AZF1 "Cele\Y56A3A.28, Cele\che-1, Cele\lin-29, Cele\scrt-1" "Xtro\LOC100488817, Xtro\zfp1, Xtro\LOC100496354, Xtro\znf577" "Mmus\Zfp853, Mmus\Zfp202, Mmus\Zfp637, Mmus\Zbtb24" "Hsap\ZNF319, Hsap\ZNF202, Hsap\ZNF32, Hsap\ZNF853" "neuroanatomy defective,viable" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC" FBgn0035159 CG13896 - http://flybase.org/reports/FBgn0035159 protein_coding_gene - - - CG13896 - CG13896 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267785 CR46116 - http://flybase.org/reports/FBgn0267785 non_protein_coding_gene - - - CR46116 - CR46116 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002370 l(3)91Fb lethal (3) 91Fb http://flybase.org/reports/FBgn0002370 FBgn0002376 gene - - - "l(DIX43)c3, C3, l(3)C3, l(3)BE52, l(3)BE51, l(3)BE50, l(3)92Ab, l(3)91Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015412 l(1)14BCa lethal (1) 14BCa http://flybase.org/reports/FBgn0015412 - gene - - - "l(1)14Ce, l(1)14-12, l(1)14BCa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031802 ppk7 pickpocket 7 http://flybase.org/reports/FBgn0031802 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK7, CG9499, ppk7" "IPR001873:Epithelial sodium channel, IPR020903:Epithelial sodium channel, conserved site" CG9499 11-Aug-17 DroID_v2017_08 "Drer\asic1a, Drer\asic2, Drer\asic1b, Drer\asic4a, Drer\asic4b, Drer\asic1c" - "Cele\asic-1, Cele\delm-1, Cele\flr-1, Cele\del-10, Cele\delm-2, Cele\unc-8, Cele\degt-1, Cele\del-1, Cele\acd-2, Cele\deg-1, Cele\mec-4, Cele\egas-1, Cele\egas-4, Cele\egas-3, Cele\asic-2, Cele\del-4, Cele\unc-105, Cele\egas-2, Cele\mec-10" "Xtro\scnn1d, Xtro\asic5, Xtro\scnn1b, Xtro\asic1, Xtro\scnn1g, Xtro\asic4, Xtro\scnn1a" "Mmus\Asic4, Mmus\Asic5, Mmus\Scnn1b, Mmus\Asic3, Mmus\Asic1, Mmus\Asic2, Mmus\Scnn1a, Mmus\Scnn1g" "Hsap\SCNN1B, Hsap\SCNN1G, Hsap\ASIC2, Hsap\ASIC5, Hsap\ASIC4, Hsap\SCNN1A, Hsap\SCNN1D, Hsap\ASIC3, Hsap\ASIC1" "viable,lethal" FBgn0025504 l(3)72Fc lethal (3) 72Fc http://flybase.org/reports/FBgn0025504 - gene - - - l(3)72Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013323 Ptth Prothoracicotropic hormone http://flybase.org/reports/FBgn0013323 FBgn0031269 protein_coding_gene cytokine activity ; GO:0005125 | inferred from electronic annotation with InterPro:IPR010345 prothoracicotrophic hormone activity ; GO:0018445 | inferred from direct assay negative phototaxis ; GO:0046957 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype regulation of endocrine process ; GO:0044060 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | inferred from mutant phenotype positive regulation of ecdysteroid biosynthetic process ; GO:0045998 | inferred from direct assay extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR010345 varicosity ; GO:0043196 | inferred from direct assay "PTTH, CG13687, Ptth, ptth, phm" "IPR029034:Cystine-knot cytokine, IPR010345:Interleukin-17 family" CG13687 11-Aug-17 DroID_v2017_08 - - - - - - "small body,developmental rate defective,size defective,viable,phototaxis defective" "wing,embryo" FBgn0264630 balloon balloon http://flybase.org/reports/FBgn0264630 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - balloon - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval dorsal trunk,embryonic/larval tracheal system,eye,somatic clone" FBgn0024762 EC66 EC66 http://flybase.org/reports/FBgn0024762 - gene - - - EC66 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,non-enhancer of variegation" FBgn0051823 CG31823 - http://flybase.org/reports/FBgn0051823 protein_coding_gene serine-type carboxypeptidase activity ; GO:0004185 | inferred from sequence or structural similarity serine-type carboxypeptidase activity ; GO:0004185 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 - "BG:DS00365.3, CG7647, CG31823" "IPR001563:Peptidase S10, serine carboxypeptidase, IPR018202:Serine carboxypeptidase, serine active site, IPR029058:Alpha/Beta hydrolase fold" CG31823 11-Aug-17 DroID_v2017_08 "Drer\scpep1, Drer\si:ch211-122f10.4, Drer\cpvl" "Scer\YBR139W, Scer\KEX1, Scer\PRC1" "Cele\F41C3.5, Cele\F13D12.6, Cele\K10C2.1, Cele\ctsa-2, Cele\Y16B4A.2, Cele\Y32F6A.5" "Xtro\cpvl, Xtro\scpep1, Xtro\ctsa" "Mmus\Cpvl, Mmus\Scpep1, Mmus\Ctsa" "Hsap\SCPEP1, Hsap\CPVL, Hsap\CTSA" viable FBgn0002080 l(2)49Fi lethal (2) 49Fi http://flybase.org/reports/FBgn0002080 - gene - - - "l(2)vr29, l(2)vr20, l(2)49Fi" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040085 p74 p74 http://flybase.org/reports/FBgn0040085 gene - - - p74 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065413 l(2)SH1560 lethal (2) SH1560 http://flybase.org/reports/FBgn0065413 gene - - - "l(2)SH1560, l(2)SH2 1560" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030638 CG11655 - http://flybase.org/reports/FBgn0030638 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002657 CG11655 "IPR002657:Bile acid:sodium symporter/arsenical resistance protein Acr3, IPR004710:Bile acid:sodium symporter" CG11655 11-Aug-17 DroID_v2017_08 "Drer\slc10a3, Drer\slc10a4, Drer\slc10a2, Drer\slc10a1" - Cele\Y71G10AR.4 "Xtro\slc10a4, Xtro\slc10a6" "Mmus\Slc10a6, Mmus\Slc10a2, Mmus\Gm5868, Mmus\Slc10a4, Mmus\Slc10a1, Mmus\Slc10a5, Mmus\Slc10a3" "Hsap\SLC10A1, Hsap\SLC10A2, Hsap\SLC10A4, Hsap\SLC10A3, Hsap\SLC10A6, Hsap\SLC10A5" "viable,fertile" FBgn0260080 2L0439 - http://flybase.org/reports/FBgn0260080 gene - "dorsal trunk growth, open tracheal system ; GO:0035001 | inferred from mutant phenotype" - 2L0439 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone,dorsal trunk primordium" FBgn0030037 Miga Mitoguardin http://flybase.org/reports/FBgn0030037 protein_coding_gene - regulation of mitochondrial fusion ; GO:0010635 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype mitochondrial fusion ; GO:0008053 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "miga, Miga, CG12125" IPR019392:Mitoguardin CG12125 11-Aug-17 DroID_v2017_08 "Drer\fam73a, Drer\fam73b" - Cele\K01D12.6 "Xtro\fam73b, Xtro\fam73a" "Mmus\Miga1, Mmus\Miga2" "Hsap\MIGA2, Hsap\MIGA1" viable FBgn0051050 CG31050 - http://flybase.org/reports/FBgn0051050 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs32b08.y1, NEST:bs32b08, CG31050" - CG31050 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0261990 CG42808 - http://flybase.org/reports/FBgn0261990 protein_coding_gene - - - "CG42808, CG13335, CG6183" "IPR027390:Endoglucanase F, domain 3" CG42808 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004741 l(3)85Dh lethal (3) 85Dh http://flybase.org/reports/FBgn0004741 - gene - - - l(3)85Dh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065518 l(2)SH1140 lethal (2) SH1140 http://flybase.org/reports/FBgn0065518 gene - - - "l(2)SH1140, l(2)SH2 1140" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001911 l(2)24Fc lethal (2) 24Fc http://flybase.org/reports/FBgn0001911 - gene - - - "jf7, l(2)jf7, l(2)24Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003201 rar1 radiation-resistant on 1 http://flybase.org/reports/FBgn0003201 - gene - - - rar1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "radiation resistant,chemical resistant" FBgn0020532 l(3)1A1 lethal (3) 1A1 http://flybase.org/reports/FBgn0020532 - gene - - - "1A1, l(3)1A1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263100 pyr::ths - http://flybase.org/reports/FBgn0263100 engineered_fusion_gene - - - pyr::ths - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267151 CR45591 - http://flybase.org/reports/FBgn0267151 non_protein_coding_gene - - - CR45591 - CR45591 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004915 TfIIB Transcription factor IIB http://flybase.org/reports/FBgn0004915 FBgn0023206 protein_coding_gene TBP-class protein binding ; GO:0017025 | inferred from electronic annotation with InterPro:IPR013150 transcription factor binding ; GO:0008134 | inferred from physical interaction with Trf DNA-templated transcriptional preinitiation complex assembly ; GO:0070897 | inferred from electronic annotation with InterPro:IPR000812 regulation of DNA binding ; GO:0051101 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4648 inferred from sequence or structural similarity with SGD:S000006290 transcriptional start site selection at RNA polymerase II promoter ; GO:0001174 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcriptional preinitiation complex ; GO:0097550 | inferred from sequence or structural similarity with SGD:S000006290 "TfIIB, dmTFIIB, TFIIB, CG5193, dTFIIB, Tfiib, dTfIIB, TfllB, tfIIb" "IPR000812:Transcription factor TFIIB, IPR013137:Zinc finger, TFIIB-type, IPR013150:Transcription factor TFIIB, cyclin-like domain, IPR013763:Cyclin-like, IPR023486:Transcription factor TFIIB, conserved site" CG5193 11-Aug-17 DroID_v2017_08 Drer\gtf2b Scer\SUA7 Cele\ttb-1 Xtro\gtf2b Mmus\Gtf2b Hsap\GTF2B embryonic stage DRSC03454 IEK -0.017377511 2.684900986 -1.726682066 -0.415752645 1.198984549 2.086247614 FBgn0019808 aos::shg argos::shg http://flybase.net/reports/FBgn0019808.html engineered_fusion_gene "gil::shg, argos::shg" 11-Aug-17 DroID_v2017_08 "visible,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing margin,posterior,wing margin bristle,posterior crossvein,posterior compartment,eye,ommatidium,interommatidial bristle,ectopic,microchaeta & mesothoracic tergumpnr-MD237,microchaeta | supernumerary & mesothoracic tergumpnr-MD237,embryonic/first instar larval cuticle,dorsal,scutum,head,wing blade" FBgn0058068 CR40068 - http://flybase.org/reports/FBgn0058068 pseudogene_attribute - - - "CR40068, CG40068" - CR40068 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266002 CR44776 - http://flybase.org/reports/FBgn0266002 non_protein_coding_gene - - - CR44776 - CR44776 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033911 VGAT Vesicular GABA Transporter http://flybase.org/reports/FBgn0033911 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 sleep ; GO:0030431 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from direct assay amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 - "CG8394.2, VIAAT, vGAT, Vgat, VGAT, CG8394" "IPR013057:Amino acid transporter, transmembrane domain" CG8394 11-Aug-17 DroID_v2017_08 "Drer\slc32a1, Drer\si:dkey-126h10.1" "Scer\AVT7, Scer\AVT1" Cele\unc-47 Xtro\slc32a1 Mmus\Slc32a1 Hsap\SLC32A1 "optomotor response defective,behavior defective,viable,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0043590 EK2-5 EK2-5 http://flybase.org/reports/FBgn0043590 gene - - - EK2-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264329 CG43788 - http://flybase.org/reports/FBgn0264329 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43788 - CG43788 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037973 CG18547 - http://flybase.org/reports/FBgn0037973 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020471 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR020471 - CG18547 "IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG18547 11-Aug-17 DroID_v2017_08 "Drer\srm, Drer\kcnab1a, Drer\kcnab2a, Drer\kcnab2b" "Scer\YPL088W, Scer\AAD14, Scer\ARA2" "Cele\C07D8.6, Cele\F53F1.2, Cele\F53F1.3, Cele\mec-14" "Xtro\srm, Xtro\kcnab2" "Mmus\Srm, Mmus\Kcnab1, Mmus\Kcnab3, Mmus\Kcnab2" "Hsap\KCNAB2, Hsap\KCNAB1, Hsap\KCNAB3, Hsap\SRM" "viable,fertile" FBgn0083272 E(smoDN)2590 Enhancer of smoDN 2590 http://flybase.org/reports/FBgn0083272 gene - - - E(smoDN)2590 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004682 grg giant ring gland http://flybase.org/reports/FBgn0004682 - gene - - - "l(1)giant ring gland, l(1)grg, grg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ring gland,neurosecretory neuron" FBgn0261531 CG42659 - http://flybase.org/reports/FBgn0261531 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42659, noncoding_3557" - CG42659 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035733 CG8641 - http://flybase.org/reports/FBgn0035733 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available "CG8641, Q9VS10" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG8641 11-Aug-17 DroID_v2017_08 "Drer\nras, Drer\ralab, Drer\rit1, Drer\rap1aa, Drer\zgc:110699, Drer\mras, Drer\zgc:153845, Drer\zgc:64022, Drer\rem1, Drer\rem2, Drer\zgc:114118, Drer\si:dkeyp-59c12.1, Drer\rhebl1, Drer\diras1a, Drer\LOC100332969, Drer\rsg1, Drer\ralbb, Drer\zgc:171704, Drer\si:dkey-27j5.5, Drer\rerglb, Drer\rasl10a, Drer\hrasb, Drer\rap2ab, Drer\si:ch73-116o1.2, Drer\rasl11a, Drer\rergla, Drer\rap1ab, Drer\diras2, Drer\rap2c, Drer\gem, Drer\hrasa, Drer\rheb, Drer\diras1b, Drer\rap2b, Drer\ralaa, Drer\ralba, Drer\rasd1, Drer\rras2, Drer\rrad, Drer\rasl12, Drer\rras, Drer\rasl11b, Drer\kras, Drer\zgc:152698" "Scer\RHB1, Scer\RAS2, Scer\RAS1, Scer\RSR1" "Cele\rsef-1, Cele\ssr-2" "Xtro\rerg, Xtro\gem, Xtro\rit1, Xtro\rasd2, Xtro\rap1b, Xtro\hras, Xtro\ras-dva, Xtro\rsg1, Xtro\rem1, Xtro\nras, Xtro\rap1a, Xtro\diras1, Xtro\rergl, Xtro\rap2b, Xtro\rrad, Xtro\rasd1, Xtro\rasl11b, Xtro\rhebl1, Xtro\ralb, Xtro\diras2, Xtro\diras3, Xtro\rheb, Xtro\kras, Xtro\rasl10a, Xtro\rem2, Xtro\LOC733456, Xtro\rala, Xtro\rap2c, Xtro\rap2a" "Mmus\Rheb, Mmus\Rasd2, Mmus\Gem, Mmus\Rasl11a, Mmus\Rhebl1, Mmus\Rsg1, Mmus\Rit1, Mmus\Kras, Mmus\Rit2, Mmus\Rrad, Mmus\Rasl10b, Mmus\Ralb, Mmus\Gm266, Mmus\Rem2, Mmus\Rap1b, Mmus\Rap1a, Mmus\Rala, Mmus\Eras, Mmus\Diras2, Mmus\Rem1, Mmus\Rergl, Mmus\Diras1, Mmus\Rap2c, Mmus\Rasl11b, Mmus\Rras2, Mmus\Nras, Mmus\Rasd1, Mmus\Hras, Mmus\Rerg, Mmus\Mras, Mmus\Rasl12, Mmus\Rap2a, Mmus\Rap2b, Mmus\Rras, Mmus\Rasl10a" "Hsap\RERGL, Hsap\DIRAS3, Hsap\RALB, Hsap\RAP2A, Hsap\KRAS, Hsap\RALA, Hsap\RASD2, Hsap\RHEB, Hsap\HRAS, Hsap\RERG, Hsap\DIRAS2, Hsap\RAP2C, Hsap\RASD1, Hsap\ERAS, Hsap\RAP1B, Hsap\RIT1, Hsap\RASL10B, Hsap\GEM, Hsap\RAP2B, Hsap\RIT2, Hsap\RRAS2, Hsap\RRAD, Hsap\REM1, Hsap\RAP1A, Hsap\RASL12, Hsap\RASL10A, Hsap\MRAS, Hsap\NRAS, Hsap\RSG1, Hsap\DIRAS1, Hsap\RASL11B, Hsap\RRAS, Hsap\RASL11A, Hsap\REM2, Hsap\RHEBL1" viable FBgn0265269 CG15425 - http://flybase.org/reports/FBgn0265269 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15425, anon-SAGE:Wang-056" - CG15425 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028630 ksh-17 ksh-17 http://flybase.org/reports/FBgn0028630 gene - - - ksh-17 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267675 CR46011 - http://flybase.org/reports/FBgn0267675 non_protein_coding_gene - - - CR46011 - CR46011 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003620 Su(var)2-142 Suppressor of variegation 2-142 http://flybase.org/reports/FBgn0003620 - gene - - - Su(var)2-142 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040613 CG12509 - http://flybase.org/reports/FBgn0040613 protein_coding_gene - - - CG12509 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267713 CR46046 - http://flybase.org/reports/FBgn0267713 non_protein_coding_gene - - - CR46046 - CR46046 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037388 CG14676 - http://flybase.org/reports/FBgn0037388 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14676 - CG14676 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065915 l(2)SH0169 lethal (2) SH0169 http://flybase.org/reports/FBgn0065915 gene - - - l(2)SH0169 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000912 fs(1)M122 female sterile (1) M122 http://flybase.org/reports/FBgn0000912 - gene - - - fs(1)M122 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0017375 l(1)lpr-1 lethal (1) lpr-1 http://flybase.org/reports/FBgn0017375 - gene - - - l(1)lpr-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "puparium,prepupal cuticle" FBgn0028230 l(3)S004209b lethal (3) S004209b http://flybase.org/reports/FBgn0028230 gene - - - "0042/09, l(3)S004209, l(3)S004209b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0037718 P58IPK P58IPK http://flybase.org/reports/FBgn0037718 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay "P58IPK, SD05682.5prime, BEST:SD05682, CG8286, dIPK" "IPR001623:DnaJ domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1" CG8286 11-Aug-17 DroID_v2017_08 "Drer\dnajc3b, Drer\dnajc7, Drer\dnajc3a" Scer\SIS1 "Cele\dnj-28, Cele\dnj-7" Xtro\dnajc3 "Mmus\Dnajc3, Mmus\Dnajc7" "Hsap\DNAJC7, Hsap\DNAJC3" viable FBgn0026163 tRNA:Lys-TTT-2-2 transfer RNA:Lysine-TTT 2-2 http://flybase.org/reports/FBgn0026163 "FBgn0003793, FBgn0011901, FBgn0051487, FBgn0060175" tRNA_gene AAA codon-amino acid adaptor activity ; GO:0033443 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033443 cytosol ; GO:0005829 | inferred by curator from GO:0033443 "CR31487, lys5:84ABc, AE002699.trna5-LysTTT, tRNA:K:TTT:AE002699-b, tRNA:K5, BG:DS00276.3, chr3R.trna78-LysTTT, tRNA-Lys-TTT-2-2, tRNA:Lys-TTT-2-2, tRNA:K5:84ABc, AAA" - CR31487 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083967 Muted Muted http://flybase.org/reports/FBgn0083967 protein_coding_gene molecular_function ; GO:0003674 | no biological data available endosomal transport ; GO:0016197 | inferred from biological aspect of ancestor with PANTHER:PTN001589637 transport vesicle ; GO:0030133 | inferred from electronic annotation with InterPro:IPR017243 BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:18561 BLOC-1 complex ; GO:0031083 | inferred from biological aspect of ancestor with PANTHER:PTN001589637 "Dromel_CG7071_FBtr0084211_uORF, CG34131, Muted, NP_001036744, muted" IPR017243:Biogenesis of lysosome-related organelles complex 1 subunit 5 CG34131 11-Aug-17 DroID_v2017_08 Drer\bloc1s5 - - - Mmus\Bloc1s5 Hsap\BLOC1S5 FBgn0032391 escl escl http://flybase.org/reports/FBgn0032391 protein_coding_gene histone methyltransferase activity ; GO:0042054 | contributes_to inferred from direct assay histone H3-K27 methylation ; GO:0070734 | inferred from genetic interaction with esc ESC/E(Z) complex ; GO:0035098 | inferred from direct assay "ESC-LIKE, CG5202, escl, ESCL, ESC, ESC1, CG5202-PA" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG5202 11-Aug-17 DroID_v2017_08 Drer\eed - Cele\mes-6 Xtro\eed "Mmus\Lrwd1, Mmus\Eed" "Hsap\LRWD1, Hsap\EED, Hsap\DAW1" "viable,fertile" FBgn0085678 CG41541 - http://flybase.org/reports/FBgn0085678 protein_coding_gene - - - CG41541 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023029 l(2)CA2 lethal (2) CA2 http://flybase.org/reports/FBgn0023029 - gene - - - l(2)CA2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011207 pelo pelota http://flybase.org/reports/FBgn0011207 - protein_coding_gene ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000091436 "nuclear-transcribed mRNA catabolic process, non-stop decay ; GO:0070481 | inferred from electronic annotation with InterPro:IPR004405 RNA surveillance ; GO:0071025 | inferred from electronic annotation with InterPro:IPR004405 meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype meiotic nuclear envelope disassembly ; GO:0051078 | inferred from mutant phenotype ribosome disassembly ; GO:0032790 | inferred from biological aspect of ancestor with PANTHER:PTN000091436 translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN000091436 spermatocyte division ; GO:0048137 | inferred from mutant phenotype meiotic G2/MI transition ; GO:0008315 | traceable author statement nuclear-transcribed mRNA catabolic process, no-go decay ; GO:0070966 | inferred from biological aspect of ancestor with PANTHER:PTN000091436 male meiosis I ; GO:0007141 | traceable author statement female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype nonfunctional rRNA decay ; GO:0070651 | inferred from biological aspect of ancestor with PANTHER:PTN000091436 germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype posttranscriptional gene silencing ; GO:0016441 | inferred from mutant phenotype" Dom34-Hbs1 complex ; GO:1990533 | inferred from physical interaction with HBS1 cytoplasm ; GO:0005737 | inferred from direct assay "ms(2)01559, CG3959, pelo" "IPR004405:Translation release factor pelota, IPR005140:eRF1 domain 1/Pelota-like, IPR005141:eRF1 domain 2, IPR005142:eRF1 domain 3, IPR029064:50S ribosomal protein L30e-like" CG3959 11-Aug-17 DroID_v2017_08 Drer\pelo "Scer\DOM34, Scer\YCL001W-A, Scer\YCL001W-B" Cele\R74.6 Xtro\pelo Mmus\Pelo Hsap\PELO embryonic stage -- adult stage "viable,fertile,male sterile,partially lethal - majority die,increased cell death,female sterile,partially,meiotic cell cycle defective,recessive,cold sensitive,wild-type" "female germline stem cell,germline cyst,follicle cell,somatic clone,egg chamber,spermatocyte,spermatid,eye,ommatidium,interommatidial bristle,ovary,germarium,Nebenkern" FBgn0014232 l(2)31Eo lethal (2) 31Eo http://flybase.org/reports/FBgn0014232 - gene - - - l(2)31Eo - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028062 l(3)S092708 lethal (3) S092708 http://flybase.org/reports/FBgn0028062 gene - - - "0927/08, l(3)S092708" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0031036 CG14220 - http://flybase.org/reports/FBgn0031036 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from biological aspect of ancestor with PANTHER:PTN001095090 histone deacetylase activity ; GO:0004407 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001095090 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN001095090 histone deacetylation ; GO:0016575 | inferred from biological aspect of ancestor with PANTHER:PTN001095090 Sin3-type complex ; GO:0070822 | inferred from direct assay "CG14220, cg14220, SDS3, Sds3" IPR013907:Sds3-like CG14220 11-Aug-17 DroID_v2017_08 "Drer\brms1la, Drer\brms1lb, Drer\suds3" "Scer\DEP1, Scer\SDS3" - "Xtro\brms1, Xtro\brms1l, Xtro\suds3" "Mmus\Brms1, Mmus\Suds3, Mmus\Brms1l" "Hsap\BRMS1, Hsap\BRMS1L, Hsap\SUDS3" FBgn0044431 LYT106 LYT106 http://flybase.org/reports/FBgn0044431 gene - - - LYT106 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264602 CR43951 - http://flybase.org/reports/FBgn0264602 non_protein_coding_gene - - - CR43951 - CR43951 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027270 l(1)G0209 lethal (1) G0209 http://flybase.org/reports/FBgn0027270 - gene - - - l(1)G0209 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,melanotic mass phenotype" melanotic mass FBgn0033174 CG11125 - http://flybase.org/reports/FBgn0033174 protein_coding_gene - - - CG11125 "IPR027710:Enkurin domain-containing protein 1, IPR027012:Enkurin domain" CG11125 11-Aug-17 DroID_v2017_08 Drer\si:ch211-220d9.3 - - Xtro\enkd1 Mmus\Enkd1 Hsap\ENKD1 viable FBgn0067070 Mpp10 Mpp10 http://flybase.org/reports/FBgn0067070 gene - - - "dMpp10, Mpp10" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001894 l(2)21Ea lethal (2) 21Ea http://flybase.org/reports/FBgn0001894 - gene - - - "l(2)neh-8, l(2)neh8, l(2)21Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016790 bose bose http://flybase.org/reports/FBgn0016790 - gene - - - bose - - 11-Aug-17 DroID_v2017_08 - - - - - - macrochaeta FBgn0015939 fs(2)PC4-U fs(2)PC4-U http://flybase.org/reports/FBgn0015939 - gene - - - "l(2)PC4-T, fs(2)PC4-T, fs(2)PC4-U" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0002037 l(2)37Da lethal (2) 37Da http://flybase.org/reports/FBgn0002037 - gene - - - "l(2)OE23, l(2)37Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,heat sensitive,visible" genitalia FBgn0013477 l(1)1Ab lethal (1) 1Ab http://flybase.org/reports/FBgn0013477 - gene - - - l(1)1Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040338 TfIIA-S-2 TfIIA-S-2 http://flybase.org/reports/FBgn0040338 protein_coding_gene "RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly ; GO:0001129 | inferred from sequence or structural similarity with TfIIA-S" transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4647 inferred from sequence or structural similarity with SGD:S000001541 transcription factor TFIIA complex ; GO:0005672 | inferred from sequence or structural similarity with HGNC:4647 inferred from sequence or structural similarity with SGD:S000001541 "CG11639, TFIIA, EG:BACR7A4.7, TfIIA-S-2, tfiia-s-2" "IPR015871:Transcription initiation factor IIA, gamma subunit, C-terminal, IPR015872:Transcription initiation factor IIA, gamma subunit, N-terminal, IPR003194:Transcription initiation factor IIA, gamma subunit, IPR009083:Transcription factor IIA, helical, IPR009088:Transcription factor IIA, beta-barrel" CG11639 11-Aug-17 DroID_v2017_08 Drer\gtf2a2 Scer\TOA2 "Cele\B0336.13, Cele\Y111B2A.13" Xtro\gtf2a2 Mmus\Gtf2a2 Hsap\GTF2A2 viable FBgn0003564 Su(Gl)57 Suppressor of Glued 57 http://flybase.org/reports/FBgn0003564 - gene - - - Su(Gl)57 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015438 l(1)5Aa lethal (1) 5Aa http://flybase.org/reports/FBgn0015438 - gene - - - l(1)5Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259405 EP-666 - http://flybase.org/reports/FBgn0259405 gene - - - EP-666 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,chaeta" FBgn0260385 GSd481 - http://flybase.org/reports/FBgn0260385 gene - - - GSd481 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0015418 l(1)16ACb lethal (1) 16ACb http://flybase.org/reports/FBgn0015418 - gene - - - l(1)16ACb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065196 l(2)SH2323 lethal (2) SH2323 http://flybase.org/reports/FBgn0065196 gene - - - "l(2)SH2323, l(2)SH2 2323" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021756 blis blisterwing http://flybase.org/reports/FBgn0021756 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "2L-F, blis" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing,somatic clone,distal" FBgn0051789 CG31789 - http://flybase.org/reports/FBgn0051789 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31789 IPR031734:Transcription activator MBF2 CG31789 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0011237 ptl pointless http://flybase.org/reports/FBgn0011237 - gene molecular_function ; GO:0003674 | no biological data available insemination ; GO:0007320 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ptl - - 11-Aug-17 DroID_v2017_08 - - - - - - male semi-sterile FBgn0267701 CR46034 - http://flybase.org/reports/FBgn0267701 non_protein_coding_gene - - - CR46034 - CR46034 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065300 l(2)SH1989 lethal (2) SH1989 http://flybase.org/reports/FBgn0065300 gene - - - "l(2)SH1989, l(2)SH2 1989" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011154 l(1)Q232 lethal (1) Q232 http://flybase.org/reports/FBgn0011154 FBgn0010210 gene - - - l(1)Q232 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013679 mt:ND1 mitochondrial NADH-ubiquinone oxidoreductase chain 1 http://flybase.org/reports/FBgn0013679 FBgn0002867 protein_coding_gene - cellular respiration ; GO:0045333 | inferred from biological aspect of ancestor with PANTHER:PTN000153361 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000153361 "CG34092, ND-1, ND1, URF1, mt:ND1, mt ND1, nd1, nad1, MT-ND1, mt-ND1" "IPR018086:NADH:ubiquinone oxidoreductase, subunit 1, conserved site, IPR001694:NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H" CG34092 11-Aug-17 DroID_v2017_08 Drer\ND1 - Cele\ND1 Xtro\ND1 Mmus\ND1 Hsap\ND1 FBgn0032429 CG5446 - http://flybase.org/reports/FBgn0032429 protein_coding_gene transcription corepressor activity ; GO:0003714 | inferred from electronic annotation with InterPro:IPR009643 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx - "BcDNA:RE36920, CG5446" IPR009643:Heat shock factor binding 1 CG5446 11-Aug-17 DroID_v2017_08 "Drer\hsbp1b, Drer\hsbp1a, Drer\hsbp1l1" - Cele\hsb-1 Xtro\hsbp1 "Mmus\Hsbp1l1, Mmus\Hsbp1" "Hsap\HSBP1L1, Hsap\HSBP1" viable FBgn0050076 CG30076 - http://flybase.org/reports/FBgn0050076 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30076 - CG30076 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0021855 l(2)k14517 lethal (2) k14517 http://flybase.org/reports/FBgn0021855 - gene - - - l(2)k14517 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029587 CG14797 - http://flybase.org/reports/FBgn0029587 protein_coding_gene - - - CG14797 - CG14797 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267311 CR45747 - http://flybase.org/reports/FBgn0267311 non_protein_coding_gene - - - CR45747 - CR45747 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085056 tre-1 tre-1 http://flybase.org/reports/FBgn0085056 - - - - "tre-1, CG34649, CR34649" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259253 EP-B5 - http://flybase.org/reports/FBgn0259253 gene - - - EP-B5 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,chaeta" FBgn0266698 CR45188 - http://flybase.org/reports/FBgn0266698 non_protein_coding_gene - - - CR45188 - CR45188 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053654 CG33654 - http://flybase.org/reports/FBgn0053654 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33654 IPR010512:Protein of unknown function DUF1091 CG33654 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266499 s-171.2 - http://flybase.org/reports/FBgn0266499 gene - - - s-171.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032321 YL-1 YL-1 http://flybase.org/reports/FBgn0032321 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR008895 histone exchange ; GO:0043486 | inferred from direct assay negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from direct assay" NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from physical interaction with UniProtKB:Q9VH07 nucleus ; GO:0005634 | inferred from direct assay "dYL-1, CG4621, YL-1, dYL1" "IPR008895:Vps72/YL1 family, IPR013272:Vps72/YL1, C-terminal" CG4621 11-Aug-17 DroID_v2017_08 "Drer\vps72, Drer\si:ch211-203d17.1" Scer\VPS72 Cele\C17E4.6 Xtro\vps72 Mmus\Vps72 Hsap\VPS72 "viable,visible,female semi-sterile,female fertile" trichogen cell DRSC23798 K -0.454799507 1.24803293 0.810624856 0.609134302 1.887901613 1.007531081 FBgn0067766 kol koldewey http://flybase.org/reports/FBgn0067766 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available kol - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "nurse cell,germline clone,egg" FBgn0001240 Hx Hexaptera http://flybase.org/reports/FBgn0001240 - gene - - - Hx - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "adult prothoracic segment,adult epidermis" FBgn0011423 l(3)j9E7 lethal (3) j9E7 http://flybase.org/reports/FBgn0011423 - gene - - - l(3)j9E7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039049 CG6726 - http://flybase.org/reports/FBgn0039049 protein_coding_gene aminoacylase activity ; GO:0004046 | inferred from electronic annotation with InterPro:IPR010159 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010159 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010159 CG6726 "IPR002933:Peptidase M20, IPR010159:N-acyl-L-amino-acid amidohydrolase, IPR011650:Peptidase M20, dimerisation domain" CG6726 11-Aug-17 DroID_v2017_08 "Drer\pm20d1.1, Drer\acy1, Drer\pm20d1.2, Drer\LOC100001620" Scer\CPS1 "Cele\C10C5.4, Cele\C06A6.4, Cele\C10C5.3, Cele\C44E12.1, Cele\C10C5.5" "Xtro\acy1.1, Xtro\pm20d1" "Mmus\Pm20d1, Mmus\Acy1" "Hsap\ABHD14A-ACY1, Hsap\PM20D1, Hsap\ACY1, Hsap\ABHD14A" viable FBgn0267824 PRAS40 Proline-rich Akt substrate 40 kDa http://flybase.org/reports/FBgn0267824 protein_coding_gene - neurotrophin TRK receptor signaling pathway ; GO:0048011 | inferred from electronic annotation with InterPro:IPR026682 negative regulation of TOR signaling ; GO:0032007 | inferred from genetic interaction with S6k TORC1 signaling ; GO:0038202 | inferred from mutant phenotype TORC1 signaling ; GO:0038202 | inferred from biological aspect of ancestor with PANTHER:PTN001094901 negative regulation of TOR signaling ; GO:0032007 | inferred from biological aspect of ancestor with PANTHER:PTN001094901 cytosol ; GO:0005829 | inferred from direct assay "CG46146, CG10109, PRAS40, dPRAS40, L" IPR026682:Proline-rich AKT1 substrate 1 protein CG46146 11-Aug-17 DroID_v2017_08 Drer\akt1s1 - - - Mmus\Akt1s1 Hsap\AKT1S1 FBgn0034849 CG3500 - http://flybase.org/reports/FBgn0034849 protein_coding_gene COPII adaptor activity ; GO:0097020 | inferred from biological aspect of ancestor with PANTHER:PTN000321972 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000321972 ER to Golgi transport vesicle ; GO:0030134 | inferred from biological aspect of ancestor with PANTHER:PTN000321972 integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000321972 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000321972 "BcDNA:AT03803, CG3500" IPR007277:Transmembrane adaptor Erv26 CG3500 11-Aug-17 DroID_v2017_08 Drer\tex261 Scer\SVP26 Cele\srh-21 Xtro\tex261 Mmus\Tex261 Hsap\TEX261 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035020 CG13585 - http://flybase.org/reports/FBgn0035020 protein_coding_gene - - - "BcDNA:AT28250, CG13585" "IPR020309:Uncharacterised protein family, CD034/YQF4" CG13585 11-Aug-17 DroID_v2017_08 Drer\smim14 - Cele\C34C12.4 Xtro\smim14 Mmus\Smim14 Hsap\SMIM14 "viable,fertile" FBgn0016798 l(1)18 lethal (1) 18 http://flybase.org/reports/FBgn0016798 - gene - - - l(1)18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0001344 l(1)1Da lethal (1) 1Da http://flybase.org/reports/FBgn0001344 - gene - - - "HM-454, HM454, l(1)1Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266518 Dpit47 DNA polymerase interacting tpr containing protein of 47kD http://flybase.org/reports/FBgn0266518 protein_coding_gene - - nucleus ; GO:0005634 | inferred from direct assay "CG3189, Dpit47, cn20" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG3189 11-Aug-17 DroID_v2017_08 "Drer\ttc12, Drer\ttc4" Scer\CNS1 Cele\C17G10.2 Xtro\ttc4 "Mmus\Ttc4, Mmus\Ttc12" "Hsap\TTC12, Hsap\TTC4" DRSC04985 E -0.379222834 -1.4049634 -2.957148118 -0.346833677 0.743502592 0.192099193 FBgn0265836 CG44625 - http://flybase.org/reports/FBgn0265836 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44625 - CG44625 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011665 Mse9.4 Modifier of split & Enhancer of split 9.4 http://flybase.org/reports/FBgn0011665 - gene - - - "MSE9.4, Mse9.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259702 CG42356 - http://flybase.org/reports/FBgn0259702 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32308, CG42356" - CG42356 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265753 CR44560 - http://flybase.org/reports/FBgn0265753 non_protein_coding_gene - - - "CR44560, lincRNA.551" - CR44560 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083250 E(smoDN)N Enhancer of smoDN group N http://flybase.org/reports/FBgn0083250 gene - smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "Group N, E(smoDN)N" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259139 glo glorund http://flybase.org/reports/FBgn0259139 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 protein binding ; GO:0005515 | inferred from physical interaction with Hrb27C inferred from physical interaction with hfp mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype regulation of translation ; GO:0006417 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype intracellular mRNA localization involved in pattern specification process ; GO:0060810 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype" protein complex ; GO:0043234 | inferred from physical interaction with Hrb27C inferred from physical interaction with hfp "p67, CG6946, l(3)S11046, cg6946, l(3)S011046, 110/46, anon-WO0118547.328, glo, Glo, p67-K" IPR000504:RNA recognition motif domain CG6946 11-Aug-17 DroID_v2017_08 "Drer\hnrnph3, Drer\grsf1, Drer\hnrnph1, Drer\esrp1, Drer\hnrnph1l, Drer\esrp2" - "Cele\hrpf-1, Cele\hrpf-2, Cele\sym-2" "Xtro\hnrnph1, Xtro\esrp1, Xtro\hnrnph3, Xtro\grsf1" "Mmus\Hnrnpf, Mmus\Grsf1, Mmus\Hnrnph2, Mmus\Hnrnph1, Mmus\Hnrnph3, Mmus\Esrp1, Mmus\Esrp2" "Hsap\ESRP1, Hsap\GRSF1, Hsap\HNRNPH3, Hsap\RPL36A, Hsap\HNRNPH1, Hsap\HNRNPF, Hsap\ESRP2, Hsap\HNRNPH2" DRSC16145 IK -0.654184709 -1.553854985 -0.614357653 -0.232783258 -1.987972557 -1.658163712 FBgn0030566 betaNACtes4 "Nascent-associated complex beta-subunit-like, testis 4" http://flybase.org/reports/FBgn0030566 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18313, betaNACtes4" IPR002715:Nascent polypeptide-associated complex NAC domain CG18313 11-Aug-17 DroID_v2017_08 "Drer\btf3l4, Drer\tab2, Drer\btf3, Drer\tab3" "Scer\BTT1, Scer\WWM1, Scer\YML020W, Scer\EGD1" Cele\icd-1 "Xtro\btf3, Xtro\btf3l4" "Mmus\Tab3, Mmus\Btf3, Mmus\Btf3l4, Mmus\Tab2" "Hsap\BTF3, Hsap\TAB3, Hsap\BTF3L4, Hsap\TAB2" viable FBgn0262809 CG43180 - http://flybase.org/reports/FBgn0262809 protein_coding_gene - - - "CG43180, chr2L_1199311_1199719.0" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005391 Yp2 Yolk protein 2 http://flybase.org/reports/FBgn0005391 "FBgn0000847, FBgn0004046" protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 neurogenesis ; GO:0022008 | inferred from mutant phenotype sex differentiation ; GO:0007548 | traceable author statement oogenesis ; GO:0048477 | traceable author statement sex differentiation ; GO:0007548 | non-traceable author statement lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay ACF complex ; GO:0016590 | NOT inferred from direct assay extracellular region ; GO:0005576 | traceable author statement "Yp2, CG2979, YP, yp2, yp, YP2, YP-2, YP[[2]], VG2, fs(1)K313, fs(1)M35, fs(1)m35, YPII, fs(1)A59, VIT2Dm" "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG2979 11-Aug-17 DroID_v2017_08 "Drer\LOC100331214, Drer\lipia, Drer\lipib, Drer\pla1a, Drer\lipca, Drer\lpl, Drer\lipg, Drer\LOC101884800" - - "Xtro\lpl, Xtro\lipg" "Mmus\Lipi, Mmus\Pnliprp1, Mmus\Pnlip, Mmus\Lpl, Mmus\Liph, Mmus\Pla1a, Mmus\Lipg, Mmus\Lipc, Mmus\Pnliprp2" "Hsap\PNLIPRP2, Hsap\LIPG, Hsap\PNLIPRP3, Hsap\LIPH, Hsap\PNLIP, Hsap\PNLIPRP1, Hsap\LIPI, Hsap\LPL, Hsap\PLA1A, Hsap\LIPC" "viable,fertile,electrophoretic variant,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0000141 ascutex ascutex http://flybase.org/reports/FBgn0000141 - gene - - intercalary heterochromatin ; GO:0005725 | non-traceable author statement "ASX, ascutex, asx" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,body color defective" "leg,mesothoracic suture,scutellum" FBgn0044062 GTD74-135-2 GTD74-135-2 http://flybase.org/reports/FBgn0044062 gene - - - GTD74-135-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031306 CG4577 - http://flybase.org/reports/FBgn0031306 protein_coding_gene - - - CG4577 IPR015943:WD40/YVTN repeat-like-containing domain CG4577 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0283465 mir-312-as mir-312-as stem loop http://flybase.org/reports/FBgn0283465 miRNA_gene - - - "mir-312-as, dme-mir-312-as" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015862 anon-2216 anon-2216 http://flybase.org/reports/FBgn0015862 - gene - - - anon-2216 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069303 X-87-21 X-87-21 http://flybase.org/reports/FBgn0069303 gene molecular_function ; GO:0003674 | no biological data available nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-87-21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,neurogenic phenotype,recessive,some die during embryonic stage" FBgn0036970 Spn77Bc Serpin 77Bc http://flybase.org/reports/FBgn0036970 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG6289, Spn77Bc, Spn77" "IPR000215:Serpin family, IPR023796:Serpin domain" CG6289 11-Aug-17 DroID_v2017_08 "Drer\serpini1, Drer\serpinf2a, Drer\serpind1, Drer\serping1, Drer\serpinf2b, Drer\agt, Drer\serpinf1" - "Cele\srp-3, Cele\srp-7, Cele\srp-8, Cele\srp-1, Cele\C28G1.2, Cele\srp-2, Cele\srp-6" "Xtro\serpinf2, Xtro\serpine1" "Mmus\Serpinf1, Mmus\Serpini1, Mmus\Agt, Mmus\Serpini2, Mmus\Serpinb7, Mmus\Serpinf2, Mmus\Serpind1" "Hsap\SERPINF1, Hsap\SERPINI1, Hsap\SERPINB7, Hsap\SERPIND1, Hsap\SERPINF2, Hsap\AGT, Hsap\SERPINI2" "lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile" DRSC10689 K -0.776142602 0.296785787 -0.246607215 -0.081125441 -0.897519964 -1.618398823 FBgn0039800 Npc2g Niemann-Pick type C-2g http://flybase.org/reports/FBgn0039800 protein_coding_gene sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 intracellular cholesterol transport ; GO:0032367 | inferred from electronic annotation with InterPro:IPR033916 sterol transport ; GO:0015918 | inferred from sequence or structural similarity with Npc2a hemolymph coagulation ; GO:0042381 | inferred from expression pattern mesoderm development ; GO:0007498 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay "BcDNA:RE56164, npc2g, Npc2g, CG11314" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set, IPR033916:ML domain, Npc2 like" CG11314 11-Aug-17 DroID_v2017_08 "Drer\npc2, Drer\zgc:193725" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 viable FBgn0030417 CG15725 - http://flybase.org/reports/FBgn0030417 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 - Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from biological aspect of ancestor with PANTHER:PTN001973695 CG15725 "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR013087:Zinc finger C2H2-type" CG15725 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039830 ATPsynC "ATP synthase, subunit C" http://flybase.org/reports/FBgn0039830 protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | inferred from biological aspect of ancestor with PANTHER:PTN000003242 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000007274" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR002379 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000003242 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProt:P48201 inferred from sequence or structural similarity with UniProt:Q06055 inferred from sequence or structural similarity with UniProtKB:P05496 ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000007274 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from biological aspect of ancestor with PANTHER:PTN000003243 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with UniProt:P48201 inferred from sequence or structural similarity with UniProt:Q06055 inferred from sequence or structural similarity with UniProtKB:P05496" "anon-EST:Posey224, CG1746, AT91, ATPsynC" "IPR000454:ATP synthase, F0 complex, subunit C, IPR002379:V-ATPase proteolipid subunit C-like domain, IPR020537:ATP synthase, F0 complex, subunit C, DCCD-binding site" CG1746 11-Aug-17 DroID_v2017_08 "Drer\atp5g3a, Drer\atp5g1, Drer\atp5g3b" "Scer\atp9, Scer\OLI1" Cele\Y82E9BR.3 "Xtro\atp5g3, Xtro\atp5g1" "Mmus\Atp5g2, Mmus\Atp5g3, Mmus\Atp5g1" "Hsap\ATP5G1, Hsap\ATP5G2, Hsap\ATP5G3" FBgn0011056 l(1)Q9 lethal (1) Q9 http://flybase.org/reports/FBgn0011056 FBgn0010210 gene - - - l(1)Q9 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034098 krimp krimper http://flybase.org/reports/FBgn0034098 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 negative regulation of oskar mRNA translation ; GO:0007319 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay "CG15707, krimp, mtc, KRIMP, Krimp" "IPR002999:Tudor domain, IPR000571:Zinc finger, CCCH-type" CG15707 11-Aug-17 DroID_v2017_08 - - - - - - "female semi-sterile,female sterile,recessive" "karyosome,chorion,chorion | germline clone" FBgn0284251 l(2)05287 lethal (2) 05287 http://flybase.org/reports/FBgn0284251 protein_coding_gene microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 cellular response to starvation ; GO:0009267 | inferred from expression pattern microtubule ; GO:0005874 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 microtubule associated complex ; GO:0005875 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 kinetochore ; GO:0000776 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 cell cortex ; GO:0005938 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 "l(2)05287, CG12050" "IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR011044:Quinoprotein amine dehydrogenase, beta chain-like" CG12050 11-Aug-17 DroID_v2017_08 "Drer\nwd1, Drer\wdr75" "Scer\ELP2, Scer\NAN1" "Cele\elpc-2, Cele\F49D11.10" Xtro\wdr75 Mmus\Wdr75 "Hsap\WDR75, Hsap\APAF1" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02151 I -1.897178203 -0.786246653 0.017748284 0.037476666 0.862965381 -0.38943408 FBgn0038642 Muc91C Mucin 91C http://flybase.org/reports/FBgn0038642 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype extracellular matrix ; GO:0031012 | inferred from sequence model "CG7709, Muc91C, Mucin 91C" IPR032059:Mucin-like domain CG7709 11-Aug-17 DroID_v2017_08 "Drer\zgc:64189, Drer\col10a1a, Drer\col8a2" "Scer\NSP1, Scer\DDR48" Cele\D1086.9 Xtro\col4a5 "Mmus\Pom121, Mmus\Sbsn, Mmus\Col25a1, Mmus\Col9a1" "Hsap\DAZ2, Hsap\COL9A1, Hsap\POM121C, Hsap\MUC1" "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC21696 I -0.525797613 2.030186698 -1.282301825 0.757747248 -0.242011862 -0.788227803 FBgn0034405 Jheh2 Juvenile hormone epoxide hydrolase 2 http://flybase.org/reports/FBgn0034405 protein_coding_gene cis-stilbene-oxide hydrolase activity ; GO:0033961 | inferred from electronic annotation with InterPro:IPR016292 - - "CT34977, DmEH, CG15102, Jheh2, jheh2" "IPR000639:Epoxide hydrolase-like, IPR010497:Epoxide hydrolase, N-terminal, IPR016292:Epoxide hydrolase, IPR029058:Alpha/Beta hydrolase fold" CG15102 11-Aug-17 DroID_v2017_08 "Drer\ephx5, Drer\ephx1, Drer\ephx4" Scer\YNR064C "Cele\dod-24, Cele\C45B11.6, Cele\Y17D7B.2, Cele\C32H11.3, Cele\ZK896.1, Cele\C49G7.12, Cele\dod-22, Cele\K08D8.5, Cele\F17C11.11, Cele\dod-21, Cele\K09D9.1, Cele\F55G11.7, Cele\K10D11.4, Cele\C49C3.9, Cele\F55G11.8, Cele\F55G11.4, Cele\C49G7.10, Cele\dct-19, Cele\ZK896.4, Cele\K10D11.2, Cele\C45B11.2, Cele\K10D11.7, Cele\K10D11.3, Cele\T05E12.6, Cele\C32H11.9, Cele\K08D8.4, Cele\C32H11.1, Cele\dod-17, Cele\ZK1037.6, Cele\F55C9.6, Cele\C06B3.6, Cele\Y17D7B.3, Cele\C29F3.7, Cele\irg-2, Cele\K10D11.5, Cele\F55G11.6, Cele\K08D8.3, Cele\K08D8.6, Cele\C49G7.7, Cele\W01A11.1, Cele\C06B3.7, Cele\F55G11.2, Cele\K10D11.6, Cele\ZK896.5, Cele\ceeh-2, Cele\T19C9.8, Cele\C32H11.4, Cele\ceeh-1" Xtro\ephx1 "Mmus\Ephx2, Mmus\Ephx3, Mmus\Ephx4, Mmus\Ephx1" "Hsap\EPHX2, Hsap\EPHX1, Hsap\ABHD8, Hsap\EPHX4, Hsap\EPHX3" viable FBgn0065622 l(2)SH0802 lethal (2) SH0802 http://flybase.org/reports/FBgn0065622 gene - - - "l(2)SH0802, l(2)SH2 0802" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038897 CG5849 - http://flybase.org/reports/FBgn0038897 protein_coding_gene peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 CG5849 "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG5849 11-Aug-17 DroID_v2017_08 "Drer\lnpep, Drer\erap1b, Drer\enpep, Drer\anpepb, Drer\erap2, Drer\erap1a, Drer\si:ch211-198g19.1, Drer\si:ch211-149p5.1, Drer\si:ch211-276a23.5, Drer\npepps, Drer\anpepa, Drer\si:ch211-106j24.1" "Scer\APE2, Scer\TMA108, Scer\AAP1" "Cele\Y53F4B.20, Cele\T07F10.1, Cele\pam-1, Cele\Y67D8C.9, Cele\AC3.5, Cele\R03G8.6, Cele\Y42A5A.1, Cele\T16G12.1, Cele\R03G8.4, Cele\F49B2.6, Cele\VB0395L.1, Cele\mnp-1, Cele\T12E12.6" "Xtro\enpep, Xtro\erap1, Xtro\npepps, Xtro\lnpep, Xtro\anpep, Xtro\lvrn" "Mmus\Anpep, Mmus\Lnpep, Mmus\Enpep, Mmus\Erap1, Mmus\Npepps, Mmus\Trhde, Mmus\Lvrn" "Hsap\ERAP1, Hsap\LVRN, Hsap\LNPEP, Hsap\ERAP2, Hsap\ANPEP, Hsap\TRHDE, Hsap\ENPEP, Hsap\NPEPPS" viable FBgn0058253 CR40253 - http://flybase.org/reports/FBgn0058253 non_protein_coding_gene - - - CR40253 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026059 Mhcl Myosin heavy chain-like http://flybase.org/reports/FBgn0026059 "FBgn0038399, FBgn0051045" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity actin-dependent ATPase activity ; GO:0030898 | NOT inferred from direct assay actin filament binding ; GO:0051015 | inferred from direct assay microfilament motor activity ; GO:0000146 | NOT inferred from direct assay" biological_process ; GO:0008150 | no biological data available "myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR002928 sarcomere ; GO:0030017 | inferred from direct assay myosin complex ; GO:0016459 | inferred from sequence or structural similarity" "CG10224, CG10218, MHCL(PDZ), DmPDZ, CG31045, Mhcl, Myo7A" "IPR000048:IQ motif, EF-hand binding site, IPR001478:PDZ domain, IPR001609:Myosin head, motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR002928:Myosin tail" CG31045 11-Aug-17 DroID_v2017_08 "Drer\LOC100331349, Drer\si:dkey-92i15.4, Drer\myhz2, Drer\myha, Drer\lnx1, Drer\myh7ba, Drer\myo18ab, Drer\myh9a, Drer\LOC100333572, Drer\LOC100329813, Drer\vmhc, Drer\vmhcl, Drer\myh11a, Drer\smyhc3, Drer\il16, Drer\pdzd7b, Drer\dlg5a, Drer\myh9b, Drer\grip1, Drer\LOC100333206, Drer\smyhc1, Drer\smyhc2, Drer\grip2b, Drer\myhc4, Drer\myo5c, Drer\myh10, Drer\grid2ipa, Drer\myo5b, Drer\LOC100537963, Drer\myhz1.1, Drer\pard3bb, Drer\myhz1.2, Drer\ns:zf-e68, Drer\inadl, Drer\slc9a3r1, Drer\myo18aa, Drer\myh6, Drer\myh14, Drer\myo5aa, Drer\myh7bb, Drer\LOC100329748, Drer\myhb" "Scer\MYO4, Scer\MYO2, Scer\MYO1" - "Xtro\lnx1, Xtro\myh9, Xtro\myo5a, Xtro\dlg5, Xtro\myh6, Xtro\myh2, Xtro\myo18b, Xtro\grip2, Xtro\myh15, Xtro\grip1, Xtro\myh13, Xtro\grid2ip, Xtro\myo5b, Xtro\myh11, Xtro\myh4, Xtro\myh8" "Mmus\Myh14, Mmus\Myo5a, Mmus\Grip1, Mmus\Myh10, Mmus\Grip2, Mmus\Myh13, Mmus\Dlg5, Mmus\Lnx1, Mmus\Pdzph1, Mmus\Patj, Mmus\Myh7b, Mmus\Mpdz, Mmus\Pdzd11, Mmus\Myh6, Mmus\Myo5c, Mmus\Myh8, Mmus\Myh11, Mmus\Myh1, Mmus\Grasp, Mmus\Pdzd2, Mmus\Ush1c, Mmus\Myo18a, Mmus\Grid2ip, Mmus\Myo5b, Mmus\Myh4, Mmus\Myo18b, Mmus\Il16, Mmus\Myh2, Mmus\Myh7, Mmus\Myh15, Mmus\Myh9" "Hsap\MPDZ, Hsap\MYH2, Hsap\LNX1, Hsap\GRID2IP, Hsap\GRIP1, Hsap\MYH13, Hsap\MYO18B, Hsap\MYO5A, Hsap\PATJ, Hsap\PDZD2, Hsap\GRASP, Hsap\MYH9, Hsap\MYH15, Hsap\MYH8, Hsap\MYO18A, Hsap\MYO5B, Hsap\MYH7B, Hsap\MYH6, Hsap\IL16, Hsap\MYO5C, Hsap\MYH1, Hsap\MYH7, Hsap\DLG5, Hsap\PARD3B, Hsap\MYH4, Hsap\MYH3, Hsap\MYH11, Hsap\MYH14, Hsap\MYH10, Hsap\USH1C, Hsap\FRMPD2" neuroanatomy defective "ventral nerve cord,peripheral nervous system" FBgn0053003 CG33003 - http://flybase.org/reports/FBgn0053003 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33003 - CG33003 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037284 CG14659 - http://flybase.org/reports/FBgn0037284 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14659 - CG14659 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC12245 I 1.507633067 0.412635702 1.013589177 1.30208749 -1.362482308 -0.878120672 FBgn0001281 janB janus B http://flybase.org/reports/FBgn0001281 FBgn0051024 protein_coding_gene phosphohistidine phosphatase activity ; GO:0008969 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 peptidyl-histidine dephosphorylation ; GO:0035971 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 sex differentiation ; GO:0007548 | inferred from expression pattern cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 "janus, bs30f02.y1, jan, jan B, Jan, CG31024, CG7931, janB, Jan-B" IPR007702:Janus CG7931 11-Aug-17 DroID_v2017_08 "Drer\phpt1, Drer\si:dkey-51e6.1" - Cele\phip-1 Xtro\phpt1 Mmus\Phpt1 Hsap\PHPT1 " spermatogenesis && adult stage , larval stage | third instar--adult stage | male " " spermatocyte

, organism

, testis | restricted

" pupal stage | late testis | restricted

viable FBgn0014298 l(3)64Bi lethal (3) 64Bi http://flybase.org/reports/FBgn0014298 - gene - - - l(3)64Bi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002311 l(3)85Ab lethal (3) 85Ab http://flybase.org/reports/FBgn0002311 - gene - - - "L2, l(3)85Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264541 CG43920 - http://flybase.org/reports/FBgn0264541 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43920, CG43920" - CG43920 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259433 C278 - http://flybase.org/reports/FBgn0259433 gene - - - C278 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta,ectopic" FBgn0065705 l(2)SH0613 lethal (2) SH0613 http://flybase.org/reports/FBgn0065705 gene - - - "l(2)SH0613, l(2)SH2 0613" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001498 l(1)10Bl lethal (1) 10Bl http://flybase.org/reports/FBgn0001498 - gene - - - l(1)10Bl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022035 l(2)k08612 lethal (2) k08612 http://flybase.org/reports/FBgn0022035 - gene - - - l(2)k08612 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001265 inb incised balloon http://flybase.org/reports/FBgn0001265 - gene - - - inb - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0026213 l(3)S027714 lethal (3) S027714 http://flybase.org/reports/FBgn0026213 - gene - - - "l(3)027714, 0277/14, 0041/08, l(3)S027714" - - 11-Aug-17 DroID_v2017_08 - - - - - - larval stage | third instar embryonic/larval proventriculus

"lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0039902 Zip102B Zinc/iron regulated transporter-related protein 102B http://flybase.org/reports/FBgn0039902 protein_coding_gene metal ion transmembrane transporter activity ; GO:0046873 | inferred from electronic annotation with InterPro:IPR003689 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003689 metal ion transport ; GO:0030001 | inferred from electronic annotation with InterPro:IPR003689 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003689 "CG2177, dZip102B, Zip102B, cg2177" IPR003689:Zinc/iron permease CG2177 11-Aug-17 DroID_v2017_08 "Drer\LOC571446, Drer\slc39a9" Scer\ATX2 Cele\T01D3.5 Xtro\slc39a9 Mmus\Slc39a9 Hsap\SLC39A9 FBgn0000516 dw dwarf http://flybase.org/reports/FBgn0000516 - gene - - - dw - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female sterile" FBgn0267750 CR46081 - http://flybase.org/reports/FBgn0267750 non_protein_coding_gene - - - "CR46081, Mgn959" - CR46081 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005755 l(1)TK310 lethal (1) TK310 http://flybase.org/reports/FBgn0005755 - gene - - - "l310, l(1)TK310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0266148 CR44854 - http://flybase.org/reports/FBgn0266148 non_protein_coding_gene - - - "CR44854, lincRNA.136" - CR44854 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034413 CG15115 - http://flybase.org/reports/FBgn0034413 protein_coding_gene - - - CG15115 - CG15115 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038589 CG18598 - http://flybase.org/reports/FBgn0038589 protein_coding_gene - - - "CT42539, CG18598" IPR025314:Domain of unknown function DUF4219 CG18598 11-Aug-17 DroID_v2017_08 - "Scer\YHL009W-A, Scer\YJL114W, Scer\YJL113W, Scer\YHL009W-B" - - - - FBgn0032824 CG13962 - http://flybase.org/reports/FBgn0032824 protein_coding_gene - - - CG13962 - CG13962 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0062649 EP417 EP417 http://flybase.org/reports/FBgn0062649 gene - - - "EP(3)0417, EP417" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262201 mir-973 mir-973 stem loop http://flybase.org/reports/FBgn0262201 miRNA_gene - - - "dme-mir-973, 973, mir-973, CR42908, miR-973" - CR42908 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014983 l(2)46Cd lethal (2) 46Cd http://flybase.org/reports/FBgn0014983 - gene - - - "433, IV, l(2)46Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005122 l(1)nd lethal no differentiation http://flybase.org/reports/FBgn0005122 - gene - - - l(1)nd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal imaginal disc primordium FBgn0259298 C503 - http://flybase.org/reports/FBgn0259298 gene - - - C503 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin" FBgn0005128 l(1)J1660 lethal (1) J1660 http://flybase.org/reports/FBgn0005128 - gene - - - l(1)J1660 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" FBgn0013970 Gebf-I glue enhancer binding factor-I http://flybase.org/reports/FBgn0013970 - gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "GEBF-I, Gebf-I" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262721 CG43165 - http://flybase.org/reports/FBgn0262721 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG43165 "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG43165 11-Aug-17 DroID_v2017_08 "Drer\spint1b, Drer\si:dkeyp-73b11.8, Drer\si:dkey-117n7.5, Drer\spint1a, Drer\tfpia, Drer\tfpi2, Drer\ambp, Drer\col6a4a, Drer\spint2" - "Cele\Y55F3BR.2, Cele\T22F7.3, Cele\F30H5.3, Cele\ZC84.1, Cele\ZC84.6, Cele\C02F12.5" "Xtro\ambp, Xtro\tfpi2, Xtro\spint2, Xtro\spint1" "Mmus\Tfpi, Mmus\Ambp, Mmus\Spint5, Mmus\Wfdc6a, Mmus\Eppin, Mmus\Spint3, Mmus\Spint1, Mmus\Tfpi2, Mmus\Spint4, Mmus\Wfdc8, Mmus\Spint2, Mmus\Wfdc6b" "Hsap\AMBP, Hsap\SPINT2, Hsap\WFDC8, Hsap\SPINT3, Hsap\EPPIN-WFDC6, Hsap\TFPI2, Hsap\TFPI, Hsap\SPINT1, Hsap\WFDC6, Hsap\SPINT4" FBgn0023086 eve::h eve::h http://flybase.org/reports/FBgn0023086 - engineered_fusion_gene - - - eve::h - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially,lethal,female limited" FBgn0036353 CG10171 - http://flybase.org/reports/FBgn0036353 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002794 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000331550 CG10171 "IPR002794:Protein of unknown function DUF92, TMEM19" CG10171 11-Aug-17 DroID_v2017_08 Drer\tmem19 - Cele\srx-128 Xtro\tmem19 Mmus\Tmem19 Hsap\TMEM19 viable FBgn0035735 Cpr65Ea Cuticular protein 65Ea http://flybase.org/reports/FBgn0035735 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr65Ea, CG8640, DmelCpr65Ea" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8640 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 Scer\QDR1 "Cele\math-34, Cele\F44F1.4, Cele\sdz-30, Cele\mes-4" - "Mmus\2410137M14Rik, Mmus\H2-K1" Hsap\ADAM2 viable FBgn0039528 dsd distracted http://flybase.org/reports/FBgn0039528 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synaptic target recognition ; GO:0008039 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CT17798, CG5634, dsd" "IPR000742:EGF-like domain, IPR000859:CUB domain, IPR002049:Laminin EGF domain, IPR013032:EGF-like, conserved site, IPR015915:Kelch-type beta propeller, IPR016201:PSI domain, IPR015916:Galactose oxidase, beta-propeller" CG5634 11-Aug-17 DroID_v2017_08 "Drer\atrnl1b, Drer\tmem145, Drer\atrn, Drer\atrnl1a" - Cele\tag-53 "Xtro\atrn, Xtro\atrnl1" "Mmus\Megf8, Mmus\Pafah1b3, Mmus\Atrnl1, Mmus\Atrn" "Hsap\ATRN, Hsap\ATRNL1, Hsap\MEGF8" viable FBgn0042180 CG18870 - http://flybase.org/reports/FBgn0042180 protein_coding_gene - - - "anon-57Fa, CG18870" - CG18870 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0050051 Tmem18 - http://flybase.org/reports/FBgn0050051 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG30051, anon-AE003822.1, Tmem18" IPR026721:Transmembrane protein 18 CG30051 11-Aug-17 DroID_v2017_08 Drer\tmem18 - Cele\srj-27 Xtro\tmem18 Mmus\Tmem18 Hsap\TMEM18 viable FBgn0003415 skd skuld http://flybase.org/reports/FBgn0003415 "FBgn0024200, FBgn0024569, FBgn0024577, FBgn0037043, FBgn0041162" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VW47 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P25008 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with HGNC:22474 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from direct assay "compound eye development ; GO:0048749 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap chaeta development ; GO:0022416 | inferred from mutant phenotype imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:22474 sex comb development ; GO:0045498 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype cell fate commitment ; GO:0045165 | inferred from genetic interaction with Scr sex comb development ; GO:0045498 | inferred from mutant phenotype inferred from genetic interaction with Scr regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay" "mediator complex ; GO:0016592 | inferred from sequence or structural similarity with HGNC:22474 mediator complex ; GO:0016592 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay core mediator complex ; GO:0070847 | inferred from physical interaction with MED17 nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from physical interaction with CycC, Cdk8" "TRAP240, dmMED13, pap, MED13, Skd/Pap/Bli, LD28662, Pap/Trap, Pap, SPH203, bli, Srb9/AMIB/PAP/TRAP240, dTRAP240, Scad78, pap/dTRAP240, bls, l(3)rK760, Skd/Med13, l(3)L7062, CG9936, skd, Trap240, Skd, dTrap240, siren9, Med13, dMED13, skd/MED13" "IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR021643:Mediator complex, subunit Med13, N-terminal, metazoa/fungi, IPR009401:Mediator complex, subunit Med13" CG9936 11-Aug-17 DroID_v2017_08 "Drer\med13a, Drer\med13b" - Cele\let-19 "Xtro\med13l, Xtro\med13" "Mmus\Med13l, Mmus\Med13" "Hsap\MED13, Hsap\MED13L" larval stage organism | ubiquitous

"lethal,viable,fertile,recessive,visible,dominant,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,partially,somatic clone,partially lethal - majority die,some die during pupal stage" "crystal cell,mitotic cell cycle,adult abdomen,maternal effect,embryonic/larval mouth,sex comb,cell autonomous,ectopic,somatic clone,prothoracic leg,distal,maxillary palpus,eye disc,photoreceptor cell,antennal disc,wing disc,leg,somatic clone - Minute background,sex comb tooth,prothoracic tarsal segment,eye,mesothoracic bristle,wing margin,wing,mesothoracic tergum" DRSC11898 IEK -0.135743256 1.897175355 -2.380304117 1.886270415 2.746434393 3.319092141 FBgn0022965 snRNPF snRNPF http://flybase.org/reports/FBgn0022965 - gene - - nucleus ; GO:0005634 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from direct assay "F, snRNPF" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259274 EP-234 - http://flybase.org/reports/FBgn0259274 gene - - - EP-234 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta" FBgn0060991 l(3)S027418 lethal (3) S027418 http://flybase.org/reports/FBgn0060991 gene - - - "0274/18, l(3)S027418" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0010700 l(2)s4831 lethal (2) s4831 http://flybase.org/reports/FBgn0010700 - gene - - - l(2)s4831 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" crystal cell FBgn0084688 tre-2 tre-2 http://flybase.org/reports/FBgn0084688 - - - - "tre-2, CG34648, CR34648" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035993 Nf-YA Nuclear factor Y-box A http://flybase.org/reports/FBgn0035993 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001289 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay" "regulation of cell cycle ; GO:0051726 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype" CCAAT-binding factor complex ; GO:0016602 | inferred from direct assay "NF-YA, dNF-YA, Nf-YA, CG3891" IPR001289:Nuclear transcription factor Y subunit A CG3891 11-Aug-17 DroID_v2017_08 "Drer\nfyal, Drer\nfya" Scer\HAP2 "Cele\nfya-2, Cele\nfya-1" Xtro\nfya Mmus\Nfya Hsap\NFYA "lethal,partially lethal - majority die,visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during third instar larval stage,some die during larval stage" "chaeta,supernumerary,mesothoracic tergum,head | pharate adult stage,eye,ommatidium,antenna,ectopic,adult thorax" FBgn0046653 anon-38D.11 anon-38D.11 http://flybase.org/reports/FBgn0046653 gene - - - "38D.11, anon-38D.11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265420 CR44332 - http://flybase.org/reports/FBgn0265420 non_protein_coding_gene - - - CR44332 - CR44332 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060341 l(3)S144002 lethal (3) S144002 http://flybase.org/reports/FBgn0060341 gene - - - "1440/02, l(3)S144002" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265414 CR44326 - http://flybase.org/reports/FBgn0265414 non_protein_coding_gene - - - CR44326 - CR44326 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046682 anon-38B.1 anon-38B.1 http://flybase.org/reports/FBgn0046682 gene - - - "38B.1, anon-38B.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014233 l(2)31Ep lethal (2) 31Ep http://flybase.org/reports/FBgn0014233 - gene - - - l(2)31Ep - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041094 scyl scylla http://flybase.org/reports/FBgn0041094 protein_coding_gene - negative regulation of signal transduction ; GO:0009968 | inferred from electronic annotation with InterPro:IPR012918 cell death ; GO:0008219 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from genetic interaction with chrb head involution ; GO:0008258 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype regulation of TOR signaling ; GO:0032006 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9NX09 "scy, CG7590, anon-WO0118547.215, scyl, scylla, 7590" IPR012918:RTP801-like CG7590 11-Aug-17 DroID_v2017_08 Drer\ddit4 - - Xtro\ddit4 "Mmus\Ddit4l, Mmus\Ddit4" "Hsap\DDIT4, Hsap\DDIT4L" "decreased cell size,somatic clone,small body,long lived,viable,fertile" FBgn0005091 fs(2)OWc3 female sterile (2) OWc3 http://flybase.org/reports/FBgn0005091 - gene - - - fs(2)OWc3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053299 CG33299 - http://flybase.org/reports/FBgn0053299 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33299 - CG33299 11-Aug-17 DroID_v2017_08 - - Cele\T26C11.2 - Mmus\Ggn "Hsap\GGN, Hsap\TPRX1" viable FBgn0037933 Ho Heme oxygenase http://flybase.org/reports/FBgn0037933 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000076411 heme oxygenase (decyclizing) activity ; GO:0004392 | inferred from direct assay heme oxidation ; GO:0006788 | inferred from biological aspect of ancestor with PANTHER:PTN000076411 heme catabolic process ; GO:0042167 | inferred from biological aspect of ancestor with PANTHER:PTN000076411 iron ion homeostasis ; GO:0055072 | inferred from biological aspect of ancestor with PANTHER:PTN000076411 heme metabolic process ; GO:0042168 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from biological aspect of ancestor with PANTHER:PTN000076411 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000076411 endomembrane system ; GO:0012505 | inferred from direct assay "CT34507, DmHO, HO, CG14716, Ho, dHO, HO-1" "IPR002051:Haem oxygenase, IPR016053:Haem oxygenase-like, IPR016084:Haem oxygenase-like, multi-helical" CG14716 11-Aug-17 DroID_v2017_08 "Drer\hmox1a, Drer\hmox2b, Drer\hmox1b, Drer\hmox2a" Scer\HMX1 - "Xtro\hmox2, Xtro\hmox1" "Mmus\Hmox2, Mmus\Hmox1" "Hsap\HMOX2, Hsap\HMOX1" "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "eye,eye disc,temperature conditional" FBgn0043543 anon-AE003534.1 anon-AE003534.1 http://flybase.org/reports/FBgn0043543 gene - - - anon-AE003534.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016803 l(1)K5 lethal (1) K5 http://flybase.org/reports/FBgn0016803 - gene - - - "l(1)K5, K5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086663 snoRNA:Psi18S-1275 snoRNA:Psi18S-1275 http://flybase.org/reports/FBgn0086663 snoRNA_gene - - - "psi18s-1275, snoRNA:783, Dm-783, snoR783, CR33625, Psi 18S-1275(SnoR783), snoRNA:Psi18S-1275" - CR33625 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029639 CG14419 - http://flybase.org/reports/FBgn0029639 protein_coding_gene - - - CG14419 - CG14419 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067350 l(3)95Eb lethal (3) 95Eb http://flybase.org/reports/FBgn0067350 gene - - - l(3)95Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034394 CG15096 - http://flybase.org/reports/FBgn0034394 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "CT42567, CG15096" "IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG15096 11-Aug-17 DroID_v2017_08 "Drer\slc17a8, Drer\slc17a6a, Drer\ppt1, Drer\slc17a6b, Drer\slc17a5, Drer\slc17a9a, Drer\si:ch1073-513e17.1, Drer\slc17a7a" "Scer\TNA1, Scer\DAL5, Scer\THI73, Scer\YIL166C, Scer\FEN2, Scer\YCT1" "Cele\C18H9.5, Cele\T19D12.9, Cele\slc-17.8, Cele\T22F3.7, Cele\Y4C6B.4, Cele\T02B11.6, Cele\F56A4.12, Cele\W04C9.6, Cele\T28H11.8, Cele\F44E7.7, Cele\cima-1, Cele\C35A5.3, Cele\C18D1.2, Cele\T01H3.3, Cele\T22F3.11, Cele\slc-17.9, Cele\F41C3.2, Cele\C01B4.7, Cele\F59A1.13, Cele\M162.5, Cele\H11E01.2, Cele\K08C7.1, Cele\slc-17.3, Cele\F10C2.7, Cele\slc-17.2, Cele\slc-17.4, Cele\Y19D10A.8, Cele\T22F3.10, Cele\Y15E3A.4, Cele\C01B4.8, Cele\Y19D10A.4, Cele\K11G9.5, Cele\slc-17.1, Cele\slc-17.5, Cele\Y4C6B.3, Cele\eat-4, Cele\F11A5.9, Cele\M117.1, Cele\vglu-2, Cele\T27D12.1, Cele\D1046.4, Cele\Y51B9A.6, Cele\Y19D10A.5, Cele\vnut-1, Cele\Y19D10A.11, Cele\C39E9.7, Cele\F56A4.10, Cele\vglu-3, Cele\R10D12.1, Cele\T22F3.8, Cele\T19D12.10" Xtro\slc17a7 "Mmus\Slc17a6, Mmus\Slc17a5, Mmus\Slc17a9, Mmus\Slc17a2, Mmus\Slc17a4, Mmus\Slc17a8, Mmus\Slc17a7, Mmus\Slc17a3, Mmus\Slc17a1" "Hsap\SLC17A7, Hsap\SLC17A6, Hsap\SLC17A8, Hsap\SLC17A1, Hsap\SLC17A5, Hsap\SLC17A4, Hsap\SLC17A2, Hsap\SLC17A3, Hsap\SLC17A9" "viable,fertile" FBgn0264413 FCE-F - http://flybase.org/reports/FBgn0264413 gene - - - FCE-F - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,somatic clone" FBgn0069154 mcl(3)Z2761 mcl(3)Z2761 http://flybase.org/reports/FBgn0069154 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z2761 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0035724 CG10064 - http://flybase.org/reports/FBgn0035724 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10064 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR033015:Cilia- and flagella-associated protein 52" CG10064 11-Aug-17 DroID_v2017_08 "Drer\wsb2, Drer\cfap52, Drer\wdr90, Drer\ambra1a, Drer\wdr5" "Scer\TUP1, Scer\SWD3" Cele\H24G06.1 "Xtro\wdr90, Xtro\ambra1, Xtro\cfap52, Xtro\wdr5" "Mmus\Cfap52, Mmus\Wdr5, Mmus\Nwd1, Mmus\Wsb2, Mmus\Wdr90, Mmus\Ambra1, Mmus\Wdr95, Mmus\Wdr38, Mmus\Wsb1" "Hsap\WDR5, Hsap\WDR5B, Hsap\CFAP52, Hsap\WSB2, Hsap\WDR90, Hsap\WDR38, Hsap\WDR88" viable FBgn0065473 l(2)SH1315 lethal (2) SH1315 http://flybase.org/reports/FBgn0065473 gene - - - "l(2)SH1315, l(2)SH2 1315" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086242 Pla2 Phospholipase A2 http://flybase.org/reports/FBgn0086242 gene - - - "Pla2, pla2, PLA[[2]]" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034683 CG13500 - http://flybase.org/reports/FBgn0034683 protein_coding_gene - - - CG13500 - CG13500 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266993 CR45444 - http://flybase.org/reports/FBgn0266993 non_protein_coding_gene - - - CR45444 - CR45444 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085628 CG41347 - http://flybase.org/reports/FBgn0085628 protein_coding_gene - - - CG41347 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040878 CG15911 - http://flybase.org/reports/FBgn0040878 protein_coding_gene - - - CG15911 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041702 CG15107 - http://flybase.org/reports/FBgn0041702 protein_coding_gene - - - CG15107 IPR028002:Myb/SANT-like DNA-binding domain CG15107 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0265191 Glycogenin Glycogenin http://flybase.org/reports/FBgn0265191 protein_coding_gene glycogenin glucosyltransferase activity ; GO:0008466 | inferred from sequence or structural similarity with RGD:621785 glycogen biosynthetic process ; GO:0005978 | inferred from sequence or structural similarity with RGD:621785 cytosol ; GO:0005829 | inferred from direct assay "CG44244, CG9480, NEST:bs16a02, Glycogenin" "IPR002495:Glycosyl transferase, family 8, IPR029044:Nucleotide-diphospho-sugar transferases" CG44244 11-Aug-17 DroID_v2017_08 "Drer\gyg2, Drer\gyg1a, Drer\gyg1b" "Scer\IDS2, Scer\GLG1, Scer\GLG2, Scer\GNT1" "Cele\gyg-2, Cele\gyg-1" "Xtro\gyg2, Xtro\gyg1" Mmus\Gyg "Hsap\GYG1, Hsap\GYG2" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0011650 Mads-2 Mads-2 http://flybase.org/reports/FBgn0011650 - gene - - - Mads-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001049 Fs(3)Hod Female sterile (3) Hodos http://flybase.org/reports/FBgn0001049 - gene molecular_function ; GO:0003674 | no biological data available pronuclear fusion ; GO:0007344 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Hod, Fs(3)Hodos, Fs(3)Sz10, Fs(3)Hod" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "male pronucleus | maternal effect,female pronucleus | maternal effect" FBgn0010223 Galphaf G protein alpha f subunit http://flybase.org/reports/FBgn0010223 - protein_coding_gene guanyl nucleotide binding ; GO:0019001 | inferred from electronic annotation with InterPro:IPR001019 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 sensory perception of chemical stimulus ; GO:0007606 | inferred from biological aspect of ancestor with PANTHER:PTN000026754 mesoderm development ; GO:0007498 | inferred from expression pattern adenylate cyclase-activating dopamine receptor signaling pathway ; GO:0007191 | inferred from biological aspect of ancestor with PANTHER:PTN000026754 positive regulation of hemocyte proliferation ; GO:0035208 | inferred from genetic interaction with hop regulation of filopodium assembly ; GO:0051489 | inferred from mutant phenotype heterotrimeric G-protein complex ; GO:0005834 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 "Galpha73B, Gfalpha, CG12232, Gf, G[[f]], GNAS/L, Galphaf, Galpha[[f]]73B, Galpha73b" "IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12232 11-Aug-17 DroID_v2017_08 "Drer\gnal, Drer\gnas, Drer\gnal2" Scer\GPA1 "Cele\gpa-10, Cele\gpa-5, Cele\gpa-18, Cele\gsa-1, Cele\gpa-6" "Xtro\gnal, Xtro\gnas" "Mmus\Gnal, Mmus\Gnas" "Hsap\GNAS, Hsap\GNAL" " adult stage && oogenesis stage , embryonic stage " " nurse cell

, oocyte

, amnioserosa

, anterior embryonic/larval midgut

, posterior embryonic/larval midgut

, gastric caecum

" "partially lethal,viable,fertile" "embryonic/larval hemocyte,filopodium" FBgn0031026 CG12231 - http://flybase.org/reports/FBgn0031026 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12231 IPR008580:PPPDE putative peptidase domain CG12231 11-Aug-17 DroID_v2017_08 "Drer\LOC794838, Drer\desi1a, Drer\desi1b, Drer\desi2" - Cele\F36D4.5 Xtro\desi1 "Mmus\Desi2, Mmus\Desi1" "Hsap\DESI1, Hsap\DESI2" viable FBgn0011107 l(1)Q68 lethal (1) Q68 http://flybase.org/reports/FBgn0011107 FBgn0010210 gene - - - l(1)Q68 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033085 CG15908 - http://flybase.org/reports/FBgn0033085 protein_coding_gene - - - CG15908 IPR021475:Protein of unknown function DUF3128 CG15908 11-Aug-17 DroID_v2017_08 Drer\si:ch211-51h9.6 Scer\EMI1 - - Mmus\2510002D24Rik Hsap\C22orf39 viable FBgn0260376 GSd468 - http://flybase.org/reports/FBgn0260376 gene - - - GSd468 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0011127 l(1)Q201 lethal (1) Q201 http://flybase.org/reports/FBgn0011127 FBgn0010210 gene - - - l(1)Q201 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060340 l(3)S144201b lethal (3) S144201b http://flybase.org/reports/FBgn0060340 gene - - - "1442/01, l(3)S144201b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052720 CG32720 - http://flybase.org/reports/FBgn0052720 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs01f06, CG32720" - CG32720 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036595 CG13046 - http://flybase.org/reports/FBgn0036595 protein_coding_gene - - - CG13046 - CG13046 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0016886 l(2)39DEk lethal (2) 39DEk http://flybase.org/reports/FBgn0016886 - gene - - - "D282, l(2)39DEk" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0278598 CR46268 - http://flybase.org/reports/FBgn0278598 non_protein_coding_gene - - - CR46268 - CR46268 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001524 l(1)11Dc lethal (1) 11Dc http://flybase.org/reports/FBgn0001524 - gene - - - l(1)11Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0083121 Uhg7 Uhg7 http://flybase.org/reports/FBgn0083121 non_protein_coding_gene - - - "Uhg7, dUhg7, CR42453, dUHG7" - CR42453 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051973 Cda5 Chitin deacetylase-like 5 http://flybase.org/reports/FBgn0051973 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from electronic annotation with InterPro:IPR002509 chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR002509, InterPro:IPR011330 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG2761, CG2776, BcDNA:RH43162, Cda5, DmCDA5, CG31973" "IPR002509:NodB homology domain, IPR002557:Chitin binding domain, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR015943:WD40/YVTN repeat-like-containing domain" CG31973 11-Aug-17 DroID_v2017_08 Drer\chid1 - "Cele\chil-10, Cele\lgx-1, Cele\chil-14, Cele\F48E3.8" - Mmus\Chid1 Hsap\CHID1 "viable,fertile" DRSC21330 IEK 1.719152867 -1.655016048 0.938005562 1.794342424 1.899090472 0.201780002 FBgn0013705 mt:tRNA:Ser-GCT mitochondrial transfer RNA:Serine-GCT http://flybase.org/reports/FBgn0013705 FBgn0002867 tRNA_gene - - - "CR34080, tRNA[Ser]GCU, mt-tRNA[Ser] (GCU), tRNA[Ser]AGY, mtdbD00006305, tRNA[Ser], mt:tRNA:Ser-GCT, mt:tRNA:S:AGY" - CR34080 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085344 CG34315 - http://flybase.org/reports/FBgn0085344 protein_coding_gene - - - CG34315 - CG34315 11-Aug-17 DroID_v2017_08 - - Cele\xbx-6 - - - FBgn0043034 l(2)42Ca lethal (2) 42Ca http://flybase.org/reports/FBgn0043034 gene - - - l(2)42Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029867 CG3847 - http://flybase.org/reports/FBgn0029867 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG3847 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG3847 11-Aug-17 DroID_v2017_08 - - "Cele\fezf-1, Cele\ces-1, Cele\hbl-1" - - - DRSC18327 I -1.692950441 0.173307437 -0.377675886 1.000185728 0.168212147 1.178618953 FBgn0014375 popeye popeye http://flybase.net/reports/FBgn0014375.html gene 11-Aug-17 DroID_v2017_08 FBgn0035685 CG13297 - http://flybase.org/reports/FBgn0035685 protein_coding_gene - - - "BcDNA:RE64858, CG13297" - CG13297 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031208 CG11023 - http://flybase.org/reports/FBgn0031208 protein_coding_gene endopeptidase activity ; GO:0004175 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 SUMO-specific protease activity ; GO:0016929 | inferred from sequence or structural similarity with SGD:S000005941 SUMO-specific protease activity ; GO:0016929 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 protein desumoylation ; GO:0016926 | inferred from sequence or structural similarity with SGD:S000005941 protein desumoylation ; GO:0016926 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 CG11023 "IPR003653:Ulp1 protease family, C-terminal catalytic domain" CG11023 11-Aug-17 DroID_v2017_08 "Drer\senp8, Drer\senp3b, Drer\senp2, Drer\eif4a1a, Drer\senp5, Drer\senp3a, Drer\si:dkey-21c19.3" Scer\ULP1 "Cele\K04F10.7, Cele\ulp-3, Cele\ulp-1" - "Mmus\Senp8, Mmus\AF366264, Mmus\Gm9839, Mmus\Senp1, Mmus\Gm5415, Mmus\Senp5, Mmus\Senp2, Mmus\Senp3, Mmus\4930444G20Rik" "Hsap\SENP2, Hsap\SENP3, Hsap\SENP1, Hsap\SENP8, Hsap\SENP5" FBgn0051804 CG31804 - http://flybase.org/reports/FBgn0051804 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs27h11, NEST:bs34f07, NEST:bs13h04, NEST:bs12c10, CG31804" - CG31804 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264574 Glut1 Glucose transporter 1 http://flybase.org/reports/FBgn0264574 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from electronic annotation with InterPro:IPR003663 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003663, InterPro:IPR005828, InterPro:IPR005829 adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "DmGluT1, Glut-1, Glut1, CG43946, Glt1, glut1, l(3)L1H, GLU, CG1086, Dmglut1, 0074/12, l(3)S007412, l(3)61Ea, DmGLUT1, CG13908, Glu T1" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR003663:Sugar/inositol transporter, IPR020846:Major facilitator superfamily domain" CG43946 11-Aug-17 DroID_v2017_08 "Drer\slc2a15a, Drer\slc2a2, Drer\slc2a3a, Drer\slc2a11l, Drer\slc2a13b, Drer\slc2a11a, Drer\slc2a9l1, Drer\LOC101882338, Drer\slc2a1b, Drer\slc2a15b, Drer\slc2a3b, Drer\LOC100331510, Drer\slc2a11b, Drer\LOC100334818, Drer\slc2a1a" "Scer\ITR2, Scer\ITR1, Scer\HXT14, Scer\YBR241C, Scer\YDR387C, Scer\VPS73" "Cele\Y39E4B.5, Cele\fgt-1, Cele\Y37A1A.3, Cele\Y39B6A.41, Cele\F53H8.3, Cele\hmit-1.3, Cele\K09C4.1, Cele\slcf-2, Cele\F13B12.2, Cele\hmit-1.2, Cele\R09B5.11, Cele\K08F9.1, Cele\K09C4.4, Cele\C03B1.13, Cele\F11D5.7, Cele\F11D5.5, Cele\K08H10.6, Cele\F48E3.2, Cele\hmit-1.1, Cele\C35A11.4, Cele\Y61A9LA.1, Cele\K09C4.5, Cele\ZK829.9, Cele\F14E5.1" "Xtro\LOC100496725, Xtro\slc2a11, Xtro\slc2a1, Xtro\slc2a5, Xtro\slc2a7, Xtro\slc2a9, Xtro\slc2a2, Xtro\slc2a3" "Mmus\Slc2a4, Mmus\Slc2a1, Mmus\Slc2a5, Mmus\Slc2a2, Mmus\Slc2a13, Mmus\Slc2a7, Mmus\Slc2a3, Mmus\Slc2a9" "Hsap\SLC2A5, Hsap\SLC2A9, Hsap\SLC2A7, Hsap\SLC2A3, Hsap\SLC2A14, Hsap\SLC2A4, Hsap\SLC2A1, Hsap\SLC2A13, Hsap\SLC2A2, Hsap\SLC2A11" FBgn0261065 Cpsf73 Cleavage and polyadenylation specificity factor 73 http://flybase.org/reports/FBgn0261065 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSU4 mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from sequence or structural similarity with protein_id:AAB70268 mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with protein_id:AAB70268 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from sequence or structural similarity with protein_id:AAB70268 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | non-traceable author statement mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from direct assay "Cpsf73, CPSF73, CPSF-73, cpsf-73, CG7698, dCPSF-73" "IPR001279:Metallo-beta-lactamase, IPR011108:Zn-dependent metallo-hydrolase, RNA specificity domain, IPR021718:Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term, IPR022712:Beta-Casp domain" CG7698 11-Aug-17 DroID_v2017_08 "Drer\cpsf3l, Drer\cpsf3" Scer\YSH1 Cele\cpsf-3 Xtro\cpsf3 "Mmus\Cpsf3, Mmus\Cpsf3l" "Hsap\CPSF3L, Hsap\CPSF3" DRSC16291 E 0.471566024 -0.003234465 1.518107582 -0.405623021 -0.418749736 -0.676282221 FBgn0025595 AkhR Adipokinetic hormone receptor http://flybase.org/reports/FBgn0025595 FBgn0043817 protein_coding_gene adipokinetic hormone receptor activity ; GO:0097003 | inferred from direct assay adipokinetic hormone binding ; GO:0097004 | inferred from physical interaction with Akh neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity carbohydrate homeostasis ; GO:0033500 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model response to peptide ; GO:1901652 | inferred from biological aspect of ancestor with PANTHER:PTN001202348 cellular response to hormone stimulus ; GO:0032870 | inferred from biological aspect of ancestor with PANTHER:PTN001202348 lipid catabolic process ; GO:0016042 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype "integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001202348 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from sequence model inferred by curator from GO:0007186,GO:0097003 integral component of membrane ; GO:0016021 | inferred from direct assay" "CG11325, DAKHR, GRHR/CG11325, DGRHR, BEST:GH19447, AkhR, akhr, AKHR, Akhr, GnRHR, DAKHR-1, GRHR, AKH-R, AkhR/GRHR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG11325 11-Aug-17 DroID_v2017_08 "Drer\gnrhr4, Drer\gpr22b, Drer\gnrhr2, Drer\gpr22a, Drer\gnrhr3, Drer\gnrhr1" - "Cele\gnrr-5, Cele\gnrr-7, Cele\gnrr-2, Cele\daf-38, Cele\gnrr-6, Cele\gnrr-3, Cele\gnrr-1" "Xtro\gnrhr2, Xtro\gnrhr, Xtro\gnrhr2/nmi" "Mmus\Gnrhr, Mmus\Gpr22" "Hsap\GNRHR, Hsap\GPR22" "viable,fertile,stress response defective" "lipid particle,adult fat body,embryonic/larval midgut" FBgn0023494 Maupiti Maupiti http://flybase.org/reports/FBgn0023494 - region - - - Maupiti - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053393 5SrRNA:CR33393 5SrRNA:CR33393 http://flybase.org/reports/FBgn0053393 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33393, 5SrRNA:CR33393" - CR33393 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065303 l(2)SH1977 lethal (2) SH1977 http://flybase.org/reports/FBgn0065303 gene - - - "l(2)SH1977, l(2)SH2 1977" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021907 l(2)k11702 lethal (2) k11702 http://flybase.org/reports/FBgn0021907 - gene - - - l(2)k11702 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264389 opm opossum http://flybase.org/reports/FBgn0264389 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence model reproduction ; GO:0000003 | inferred from mutant phenotype regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype positive regulation of Wnt protein secretion ; GO:0061357 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from sequence model endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG9053, opm, opo, p24" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG9053 11-Aug-17 DroID_v2017_08 "Drer\tmed6, Drer\tmed5, Drer\tmed1a, Drer\tmed1b, Drer\tmed7" "Scer\ERP3, Scer\EMP24, Scer\ERP4, Scer\ERP2" "Cele\F57B10.5, Cele\K08E4.6" "Xtro\tmed5, Xtro\tmed6, Xtro\tmed7, Xtro\tmed1" "Mmus\Tmed1, Mmus\Tmed7, Mmus\Tmed6, Mmus\Tmed3, Mmus\Tmed5" "Hsap\TMED1, Hsap\TMED6, Hsap\TMED5, Hsap\TMED3, Hsap\TMED7-TICAM2" DRSC22135 IEK 1.187507653 1.776691718 1.981034054 0.690165731 0.832875937 1.967223728 FBgn0058298 CG40298 - http://flybase.org/reports/FBgn0058298 protein_coding_gene - - - CG40298 - CG40298 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22274 IE 0.301637306 1.772498418 0.201109496 1.593466778 1.164481439 0.195856927 FBgn0053658 CG33658 - http://flybase.org/reports/FBgn0053658 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1056, CG33658" IPR010512:Protein of unknown function DUF1091 CG33658 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0001677 l(1)EN15 lethal (1) from Eugene Nonautonomous 15 http://flybase.org/reports/FBgn0001677 - gene - - - l(1)EN15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264376 CR43828 - http://flybase.org/reports/FBgn0264376 non_protein_coding_gene - - - CR43828 - CR43828 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024219 ird9 immune response deficient 9 http://flybase.org/reports/FBgn0024219 - gene - positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype - "ird, ird9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,immune response defective,recessive,melanotic mass phenotype" melanotic mass FBgn0024183 vig vasa intronic gene http://flybase.org/reports/FBgn0024183 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence model heterochromatin organization ; GO:0070828 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from physical interaction with AGO2 RISC complex ; GO:0016442 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay RISC complex ; GO:0016442 | inferred from physical interaction with AGO2 polytene chromosome ; GO:0005700 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "VIG, EP(2)0812, BG:DS00929.13, CG4170, vig, Vig" IPR006861:Hyaluronan/mRNA-binding protein CG4170 11-Aug-17 DroID_v2017_08 "Drer\zgc:103482, Drer\serbp1a, Drer\serbp1b" "Scer\STM1, Scer\STF2, Scer\TMA10" Cele\vig-1 "Xtro\serbp1, Xtro\habp4" "Mmus\Habp4, Mmus\Serbp1" "Hsap\SERBP1, Hsap\HABP4" "viable,fertile,female sterile,suppressor of variegation,dominant" embryonic/larval salivary gland FBgn0035370 Non2 Novel nucleolar protein 2 http://flybase.org/reports/FBgn0035370 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay "CG1240, Non2" "IPR003121:SWIB/MDM2 domain, IPR014876:DEK, C-terminal, IPR019835:SWIB domain" CG1240 11-Aug-17 DroID_v2017_08 "Drer\smarcd3a, Drer\smarcd2, Drer\smarcd3b, Drer\smarcd1" "Scer\SNF12, Scer\RSC6, Scer\UAF30, Scer\TRI1" "Cele\swsn-2.2, Cele\ham-3, Cele\T24G10.2" Xtro\smarcd2 "Mmus\Smarcd1, Mmus\Smarcd3, Mmus\Smarcd2" "Hsap\SMARCD3, Hsap\SMARCD1, Hsap\SMARCD2" "viable,visible,lethal" trichogen cell FBgn0000452 dil dilute http://flybase.org/reports/FBgn0000452 - gene - - - dil - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0265182 CG44247 - http://flybase.org/reports/FBgn0265182 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009635 cellular_component ; GO:0005575 | no biological data available "CG44247, CG3749, CG30420" IPR009635:Neural proliferation differentiation control-1 CG44247 11-Aug-17 DroID_v2017_08 "Drer\npdc1b, Drer\npdc1a" - Cele\cab-1 - Mmus\Npdc1 Hsap\NPDC1 viable FBgn0264726 CR43994 - http://flybase.org/reports/FBgn0264726 non_protein_coding_gene - - - CR43994 - CR43994 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260614 2L883 - http://flybase.org/reports/FBgn0260614 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L883 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "dorsal air sac primordium,somatic clone" FBgn0265985 CR44764 - http://flybase.org/reports/FBgn0265985 non_protein_coding_gene - - - "lincRNA.377, CR44764" - CR44764 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034651 CG15676 - http://flybase.org/reports/FBgn0034651 protein_coding_gene tubulin binding ; GO:0015631 | inferred from biological aspect of ancestor with PANTHER:PTN000274575 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR016655 microtubule-based process ; GO:0007017 | inferred from biological aspect of ancestor with PANTHER:PTN000274575 tubulin complex assembly ; GO:0007021 | inferred from biological aspect of ancestor with PANTHER:PTN000274575 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000274575 prefoldin complex ; GO:0016272 | inferred from biological aspect of ancestor with PANTHER:PTN000274575 polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN000274575 CG15676 "IPR004127:Prefoldin alpha-like, IPR016655:Prefoldin subunit 3" CG15676 11-Aug-17 DroID_v2017_08 "Drer\vbp1, Drer\pfdn5" "Scer\GIM5, Scer\PAC10" "Cele\pfd-3, Cele\pfd-5" Xtro\vbp1 "Mmus\Pfdn5, Mmus\Vbp1" "Hsap\PFDN5, Hsap\VBP1" viable DRSC27015 K 0.313234376 -0.247144738 -0.25080294 -0.185405363 1.969298654 1.080663229 FBgn0061041 l(3)S023809 lethal (3) S023809 http://flybase.org/reports/FBgn0061041 gene - - - "0238/09, l(3)S023809" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal" FBgn0039430 CG5455 - http://flybase.org/reports/FBgn0039430 protein_coding_gene molecular_function ; GO:0003674 | no biological data available extracellular matrix organization ; GO:0030198 | inferred from sequence or structural similarity with MGI:MGI:2447813 proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with MGI:MGI:2447813 "CT17296, CG5455" IPR029058:Alpha/Beta hydrolase fold CG5455 11-Aug-17 DroID_v2017_08 Drer\serac1 - Cele\F17H10.1 - Mmus\Serac1 Hsap\SERAC1 "viable,fertile" FBgn0052479 Usp10 Ubiquitin specific protease 10 http://flybase.org/reports/FBgn0052479 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:12608 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:12608 cytosol ; GO:0005829 | inferred from direct assay "CG13903, CG12503, Usp10, CG32479, Q9W0L7" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG32479 11-Aug-17 DroID_v2017_08 Drer\usp10 "Scer\UBP3, Scer\UBP1" Cele\usp-3 Xtro\usp10 "Mmus\Usp10, Mmus\Galnt2" Hsap\USP10 "visible,lethal,viable,fertile" "scutellar bristle,wing,supernumerary" FBgn0262371 mir-263b mir-263b stem loop http://flybase.org/reports/FBgn0262371 miRNA_gene - negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from direct assay compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with bft chaeta development ; GO:0022416 | inferred from genetic interaction with bft - "dme-mir-263b, mir-263b, miR-263b, CR42886, CR33581, miR-263, dme-miR-263b" - CR42886 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "eye,wing,wing vein,wing margin,interommatidial bristle" FBgn0051815 CG31815 - http://flybase.org/reports/FBgn0051815 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31815 IPR031958:Protein of unknown function DUF4778 CG31815 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0002098 l(2)57Cd lethal (2) 57Cd http://flybase.org/reports/FBgn0002098 - gene - - - l(2)57Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085583 CG41258 - http://flybase.org/reports/FBgn0085583 protein_coding_gene - - - CG41258 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004742 l(3)85Di lethal (3) 85Di http://flybase.org/reports/FBgn0004742 - gene - - - l(3)85Di - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028609 l(2)W16 lethal (2) W16 http://flybase.org/reports/FBgn0028609 gene - - - "l(2R)W16, l(2)W16" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015981 l(2)PC4-G lethal (2) PC4-G http://flybase.org/reports/FBgn0015981 - gene - - - "l(2)PC4-J, l(2)PC4-G" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033754 Ak6 Adenylate kinase 6 http://flybase.org/reports/FBgn0033754 protein_coding_gene adenylate kinase activity ; GO:0004017 | inferred from direct assay ATP binding ; GO:0005524 | inferred from biological aspect of ancestor with PANTHER:PTN000287630 cellular response to starvation ; GO:0009267 | inferred from expression pattern nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000287630 "Ak6, DAK6, CG8816" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020618:Adenylate kinase isoenzyme 6" CG8816 11-Aug-17 DroID_v2017_08 Drer\zgc:86811 Scer\FAP7 Cele\E02H1.6 Xtro\ak6 "Mmus\Ak6, Mmus\Taf9" "Hsap\AK6, Hsap\TAF9" viable FBgn0061207 MS101a MS101a http://flybase.org/reports/FBgn0061207 gene - - - "gst-3,2, MS101a" - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0026751 XRCC1 XRCC1 http://flybase.org/reports/FBgn0026751 - protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR002706 "single strand break repair ; GO:0000012 | inferred from electronic annotation with InterPro:IPR002706 base-excision repair, AP site formation ; GO:0006285 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR002706 "Xrcc1, CG4208, XRCC1, 4208" "IPR001357:BRCT domain, IPR002706:DNA-repair protein Xrcc1, N-terminal, IPR008979:Galactose-binding domain-like" CG4208 11-Aug-17 DroID_v2017_08 "Drer\trpc2b, Drer\zgc:110224, Drer\xrcc1" - Cele\T27A8.4 "Xtro\trpc2, Xtro\xrcc1" "Mmus\Trpc2, Mmus\Xndc1, Mmus\Xrcc1" Hsap\XRCC1 "viable,fertile,visible" "chaeta,trichogen cell" FBgn0261845 pre-mod(mdg4)-U - http://flybase.org/reports/FBgn0261845 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-U, CG42777, RU" "IPR007588:Zinc finger, FLYWCH-type" CG42777 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010741 Pfdn2 Prefoldin 2 http://flybase.org/reports/FBgn0010741 "FBgn0011417, FBgn0036123" protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR002777 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000329566 oogenesis ; GO:0048477 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000329566 establishment or maintenance of neuroblast polarity ; GO:0045196 | inferred from mutant phenotype prefoldin complex ; GO:0016272 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000329566 prefoldin complex ; GO:0016272 | inferred from direct assay "CG6302, P01239, l(3)j9B4, l(3)01239, Pfdn2, pfdn2" "IPR002777:Prefoldin beta-like, IPR027235:Prefoldin subunit 2" CG6302 11-Aug-17 DroID_v2017_08 Drer\pfdn2 Scer\GIM4 Cele\pfd-2 Xtro\pfdn2 Mmus\Pfdn2 Hsap\PFDN2 "lethal,recessive,female sterile,visible,partially lethal - majority die,some die during pupal stage" "ovariole,germline clone,oocyte,embryonic/larval brain,trichogen cell" FBgn0083262 E(smoDN)786 Enhancer of smoDN 786 http://flybase.org/reports/FBgn0083262 gene - - - E(smoDN)786 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035490 CG1136 - http://flybase.org/reports/FBgn0035490 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 - - "novel, CG1136" IPR000618:Insect cuticle protein CG1136 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038416 CG17930 - http://flybase.org/reports/FBgn0038416 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 CG17930 "IPR020846:Major facilitator superfamily domain, IPR005828:Major facilitator, sugar transporter-like" CG17930 11-Aug-17 DroID_v2017_08 "Drer\slc2a10, Drer\slc2a12, Drer\LOC101882338, Drer\slc2a8, Drer\slc2a6, Drer\slc2a13b" "Scer\MPH3, Scer\VBA5, Scer\HXT1, Scer\ITR1, Scer\YMR279C, Scer\GEX1, Scer\RGT2, Scer\MAL31, Scer\HXT10, Scer\ITR2, Scer\HXT2, Scer\HXT13, Scer\HXT6, Scer\HXT17, Scer\VBA1, Scer\STL1, Scer\SGE1, Scer\VBA4, Scer\YDR387C, Scer\VBA3, Scer\HXT14, Scer\HXT11, Scer\HXT16, Scer\HXT7, Scer\MPH2, Scer\HXT5, Scer\HXT3, Scer\SNF3, Scer\YDL199C, Scer\AZR1, Scer\HXT8, Scer\ATR1, Scer\GEX2, Scer\YFL040W, Scer\GAL2, Scer\VBA2, Scer\MAL11, Scer\HXT9, Scer\HXT15, Scer\HXT4, Scer\ENB1" "Cele\fgt-1, Cele\hmit-1.2" "Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a6, Xtro\slc2a12" "Mmus\Slc2a10, Mmus\Slc2a6, Mmus\Slc2a8, Mmus\Slc2a12, Mmus\Slc2a13" "Hsap\SLC2A10, Hsap\SLC2A13, Hsap\SLC2A6, Hsap\SLC2A12, Hsap\SLC2A8" viable FBgn0039064 CG4467 - http://flybase.org/reports/FBgn0039064 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "CG13825, CG4467" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG4467 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-106j24.1, Drer\erap1a, Drer\enpep, Drer\lnpep, Drer\si:ch211-276a23.5, Drer\erap1b, Drer\si:ch211-198g19.1, Drer\npepps, Drer\anpepb, Drer\erap2, Drer\anpepa, Drer\si:ch211-149p5.1" "Scer\TMA108, Scer\AAP1, Scer\APE2" "Cele\Y53F4B.20, Cele\pam-1, Cele\VB0395L.1, Cele\R03G8.6, Cele\F49B2.6, Cele\mnp-1, Cele\Y67D8C.9, Cele\T07F10.1, Cele\AC3.5, Cele\T16G12.1, Cele\T12E12.6, Cele\Y42A5A.1, Cele\R03G8.4" "Xtro\npepps, Xtro\erap1, Xtro\anpep, Xtro\enpep, Xtro\lnpep, Xtro\lvrn" "Mmus\Erap1, Mmus\Enpep, Mmus\Trhde, Mmus\Anpep, Mmus\Npepps, Mmus\Lvrn, Mmus\Lnpep" "Hsap\LNPEP, Hsap\ANPEP, Hsap\NPEPPS, Hsap\ERAP1, Hsap\ENPEP, Hsap\TRHDE, Hsap\ERAP2, Hsap\LVRN" viable DRSC14675 E 0.228041432 0.275159701 1.591409726 0.111235047 0.29627186 -0.43312686 FBgn0053877 His4:CG33877 His4:CG33877 http://flybase.org/reports/FBgn0053877 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33877, His4:CG33877" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33877 11-Aug-17 DroID_v2017_08 "Drer\LOC100331412, Drer\si:ch73-368j24.14, Drer\zgc:194989, Drer\si:ch211-113a14.17, Drer\si:dkey-108k21.19, Drer\LOC570405, Drer\si:dkey-261m9.18, Drer\zgc:154164, Drer\zgc:153409, Drer\si:dkey-261m9.17, Drer\si:ch211-113a14.6, Drer\LOC100150038, Drer\hist1h4l, Drer\si:ch73-36p18.3, Drer\LOC794549, Drer\LOC562770, Drer\si:ch73-36p18.4, Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.26, Drer\LOC100329358, Drer\si:dkey-108k21.12, Drer\si:dkey-108k21.28, Drer\zgc:163040" "Scer\HHF1, Scer\HHF2" "Cele\his-1, Cele\his-31, Cele\his-18, Cele\his-10, Cele\his-46, Cele\his-38, Cele\his-14, Cele\his-64, Cele\his-37, Cele\his-50, Cele\his-26, Cele\his-5, Cele\his-67, Cele\his-56, Cele\his-60, Cele\his-28" "Xtro\LOC100493041, Xtro\hist1h4c, Xtro\hist1h4k" "Mmus\Hist2h4, Mmus\Hist1h4m, Mmus\Hist1h4n, Mmus\Hist1h4a, Mmus\Hist1h4c, Mmus\Hist1h4j, Mmus\Hist4h4, Mmus\Hist1h4b, Mmus\Hist1h4h, Mmus\Hist1h4f, Mmus\Hist1h4k, Mmus\Hist1h4i, Mmus\Hist1h4d" "Hsap\HIST1H4E, Hsap\HIST1H4I, Hsap\HIST1H4B, Hsap\HIST1H4C, Hsap\HIST1H4A, Hsap\HIST1H4H, Hsap\HIST1H4J, Hsap\HIST1H4G, Hsap\HIST2H4A, Hsap\HIST1H4F, Hsap\HIST1H4D, Hsap\HIST1H4K, Hsap\HIST1H4L, Hsap\HIST2H4B, Hsap\HIST4H4" FBgn0010939 l(3)10112 lethal (3) 10112 http://flybase.org/reports/FBgn0010939 - gene - - - l(3)10112 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262819 CG43190 - http://flybase.org/reports/FBgn0262819 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43190, DMG8-chr2R.14.008" - CG43190 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038142 CheA87a Chemosensory protein A 87a http://flybase.org/reports/FBgn0038142 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheA29a extracellular region ; GO:0005576 | inferred from sequence model "CG14379, CheA87a" IPR010512:Protein of unknown function DUF1091 CG14379 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264379 CR43831 - http://flybase.org/reports/FBgn0264379 non_protein_coding_gene - - - CR43831 - CR43831 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014427 CG11899 - http://flybase.org/reports/FBgn0014427 FBgn0039649 protein_coding_gene O-phospho-L-serine:2-oxoglutarate aminotransferase activity ; GO:0004648 | inferred from biological aspect of ancestor with PANTHER:PTN000475583 L-serine biosynthetic process ; GO:0006564 | inferred from biological aspect of ancestor with PANTHER:PTN000475583 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000475583 "ESTS:39C10S, 39C10S, anon-sts29, CG11899, Ov8" "IPR000192:Aminotransferase class V domain, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase, IPR020578:Aminotransferase class-V, pyridoxal-phosphate binding site, IPR022278:Phosphoserine aminotransferase" CG11899 11-Aug-17 DroID_v2017_08 Drer\psat1 Scer\SER1 "Cele\F26H9.5, Cele\agxt-1" Xtro\psat1 Mmus\Psat1 Hsap\PSAT1 viable FBgn0027109 NPF neuropeptide F http://flybase.org/reports/FBgn0027109 - protein_coding_gene neuropeptide hormone activity ; GO:0005184 | inferred from mutant phenotype neuropeptide F receptor binding ; GO:0071859 | inferred from physical interaction with NPFR neuropeptide hormone activity ; GO:0005184 | traceable author statement neuropeptide hormone activity ; GO:0005184 | non-traceable author statement larval locomotory behavior ; GO:0008345 | traceable author statement larval feeding behavior ; GO:0030536 | inferred from mutant phenotype regulation of response to food ; GO:0032095 | inferred from mutant phenotype circadian behavior ; GO:0048512 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern neuropeptide signaling pathway ; GO:0007218 | traceable author statement larval foraging behavior ; GO:0035177 | inferred from mutant phenotype social behavior ; GO:0035176 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay circadian rhythm ; GO:0007623 | inferred from expression pattern neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "dnpf, NPF, Dm-NPF, NPF-A2, NPF-A1, NPF89D3, dNPF, NP-PP, CG10342, Drm-NPF, npf, Npf, DmNPF" - CG10342 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,developmental rate defective,conditional,chemical sensitive,feeding behavior defective,viable" FBgn0027599 CG2790 - http://flybase.org/reports/FBgn0027599 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003604 - - "BcDNA:GH03108, CG2790" "IPR001623:DnaJ domain, IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR018253:DnaJ domain, conserved site, IPR013087:Zinc finger C2H2-type, IPR022755:Zinc finger, double-stranded RNA binding" CG2790 11-Aug-17 DroID_v2017_08 "Drer\dnajb2, Drer\dnajc22, Drer\dnajb4, Drer\dnajc21, Drer\dnajb1a, Drer\dnajb5" "Scer\APJ1, Scer\JJJ1, Scer\ERJ5, Scer\SCJ1" "Cele\dnj-19, Cele\dnj-26, Cele\dnj-12, Cele\dnj-22, Cele\F54F2.9, Cele\dnj-17, Cele\dnj-1, Cele\dnj-13" Xtro\dnajc21 "Mmus\Dnajb5, Mmus\Dnajc22, Mmus\Dnajb1, Mmus\Dnajc21, Mmus\Dnajb4" "Hsap\DNAJC21, Hsap\DNAJB1, Hsap\DNAJB5, Hsap\DNAJC22, Hsap\DNAJB4" "viable,visible" trichogen cell FBgn0020414 Idgf3 Imaginal disc growth factor 3 http://flybase.org/reports/FBgn0020414 - protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 imaginal disc growth factor receptor binding ; GO:0008084 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 wound healing ; GO:0042060 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from direct assay chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "IDGF3, CG4559, IDGF-3, idgf3, BG:DS02780.2, IDGF, Idgf3, DmIDGF3, lincRNA.163" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG4559 11-Aug-17 DroID_v2017_08 "Drer\ovgp1, Drer\si:ch211-226m16.2, Drer\chia.6, Drer\chia.4, Drer\chia.2, Drer\chia.5, Drer\chia.3" Scer\CTS2 "Cele\chil-19, Cele\chil-24, Cele\lmd-4, Cele\lmd-5, Cele\chil-8, Cele\chil-4, Cele\chil-7, Cele\chil-2, Cele\cht-2, Cele\chil-6, Cele\chil-16, Cele\chil-17, Cele\chil-12, Cele\chil-23, Cele\chil-11, Cele\chil-3, Cele\chil-20, Cele\chil-25, Cele\chil-18, Cele\chil-22, Cele\chil-15, Cele\T19H5.6, Cele\chil-5, Cele\chil-13" "Xtro\chit1, Xtro\ctbs, Xtro\LOC548945, Xtro\chia" "Mmus\Chit1, Mmus\Chil1, Mmus\Chil6, Mmus\Chia1, Mmus\Ovgp1, Mmus\Chil3, Mmus\Ctbs, Mmus\Chil5, Mmus\Chil4" "Hsap\CHIT1, Hsap\CHI3L2, Hsap\CHI3L1, Hsap\CHIA, Hsap\OVGP1" " larval stage | third instar , adult stage && oogenesis stage , embryonic stage , embryonic stage && larval stage " " ring gland

, oocyte

, amnioproctodeal invagination | vicinity of

, embryonic/larval tracheal system

, ventral furrow | vicinity of

, embryonic/larval fat body

, nurse cell

, imaginal disc

, larval optic lobe

, yolk

, embryonic/larval salivary gland

, larval brain

, cephalic furrow | vicinity of

, lymph gland

" viable FBgn0064766 CG7600 - http://flybase.org/reports/FBgn0064766 protein_coding_gene - - - CG7600 "IPR028091:FAM91, N-terminal domain, IPR028097:FAM91, C-terminal domain" CG7600 11-Aug-17 DroID_v2017_08 "Drer\aclya, Drer\fam91a1, Drer\aclyb" - "Cele\F33H2.2, Cele\acly-2" "Xtro\fam91a1, Xtro\acly" Mmus\Fam91a1 "Hsap\FAM91A1, Hsap\ACLY" viable FBgn0259547 GG01546 - http://flybase.org/reports/FBgn0259547 gene - - - GG01546 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0021977 l(2)k09923 lethal (2) k09923 http://flybase.org/reports/FBgn0021977 - gene - - - l(2)k09923 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000922 fs(1)ne9 female sterile (1) no eggs 9 http://flybase.org/reports/FBgn0000922 - gene - - - "ne9, fs(1)ne[9], fs(1)ne9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,recessive,female sterile" "dorsal appendage,chorion,endochorion,oocyte" FBgn0040926 CG15334 - http://flybase.org/reports/FBgn0040926 protein_coding_gene - - - CG15334 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019875 anon-92Da anon-92Da http://flybase.org/reports/FBgn0019875 - gene - - - anon-92Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,partially lethal - majority die" eye FBgn0010353 Nc94B Neural conserved at 94B http://flybase.org/reports/FBgn0010353 - gene - - - "nPKC, Nc94B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051741 CG31741 - http://flybase.org/reports/FBgn0051741 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "CG5750, CG31741" IPR002159:CD36 family CG31741 11-Aug-17 DroID_v2017_08 "Drer\scarb2, Drer\LOC564077, Drer\cd36, Drer\scarb1" - "Cele\scav-3, Cele\scav-2, Cele\scav-5, Cele\scav-1" "Xtro\cd36, Xtro\scarb2, Xtro\scarb1" "Mmus\Scarb1, Mmus\Cd36, Mmus\Scarb2" "Hsap\SCARB1, Hsap\CD36, Hsap\SCARB2" viable FBgn0025558 CG4101 - http://flybase.org/reports/FBgn0025558 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009621 "anon73B1, anon-73B1, CG4101" IPR009621:Uncharacterised protein family UPF0239 CG4101 11-Aug-17 DroID_v2017_08 Drer\manbal - - - Mmus\Manbal Hsap\MANBAL viable FBgn0030808 RhoGAP15B Rho GTPase activating protein at 15B http://flybase.org/reports/FBgn0030808 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence model GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with HGNC:16925 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 regulation of GTPase activity ; GO:0043087 | inferred from sequence model imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:16925" Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:16925 "CG4937, RhoGAP15B, gap20" "IPR000198:Rho GTPase-activating protein domain, IPR001849:Pleckstrin homology domain, IPR008936:Rho GTPase activation protein, IPR029071:Ubiquitin-related domain, IPR011993:PH domain-like" CG4937 11-Aug-17 DroID_v2017_08 "Drer\agfg1b, Drer\zmp:0000000660, Drer\LOC100005008, Drer\si:ch211-135f11.1, Drer\agfg1a, Drer\arap3" Scer\GTS1 Cele\F23H11.4 Xtro\arap3 "Mmus\Arap1, Mmus\Arap2, Mmus\Arap3, Mmus\Agfg1" "Hsap\ARAP2, Hsap\ARAP3, Hsap\AGFG1, Hsap\ARAP1" partially lethal - majority die FBgn0005532 l(2)57Df lethal (2) 57Df http://flybase.org/reports/FBgn0005532 - gene - - - l(2)57Df - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262872 milt milton http://flybase.org/reports/FBgn0262872 protein_coding_gene myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A microtubule motor activity ; GO:0003777 | inferred from mutant phenotype mitochondrion distribution ; GO:0048311 | inferred from mutant phenotype Nebenkern assembly ; GO:0007287 | inferred from mutant phenotype sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype axonal transport of mitochondrion ; GO:0019896 | inferred from expression pattern inferred from mutant phenotype establishment of mitochondrion localization ; GO:0051654 | inferred from mutant phenotype axonal transport of mitochondrion ; GO:0019896 | inferred from direct assay phototransduction ; GO:0007602 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "milt, CG43227, CG13777, l(2)k04704, anon-WO0153538.19, CG31630, Milt, Milton" "IPR006933:HAP1, N-terminal, IPR022154:Trafficking kinesin-binding protein domain" CG43227 11-Aug-17 DroID_v2017_08 "Drer\trak2, Drer\si:dkey-28e7.3, Drer\trak1" - "Cele\T23F2.2, Cele\trak-1" "Xtro\hap1, Xtro\trak1" "Mmus\Trak1, Mmus\Trak2, Mmus\Ccdc64b, Mmus\Hap1" "Hsap\HAP1, Hsap\TRAK1, Hsap\TRAK2" FBgn0063437 ferm ferm http://flybase.org/reports/FBgn0063437 gene - - - ferm - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066101 LpR1 Lipophorin receptor 1 http://flybase.org/reports/FBgn0066101 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 receptor activity ; GO:0004872 | inferred from mutant phenotype" receptor-mediated endocytosis ; GO:0006898 | inferred from expression pattern inferred from mutant phenotype - "CG31094, CT15569, CG4861, CG4874, CG4870, CG31095, LpR1, lpr1" "IPR009030:Growth factor receptor cysteine-rich domain, IPR018097:EGF-like calcium-binding, conserved site, IPR000033:LDLR class B repeat, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG31094 11-Aug-17 DroID_v2017_08 "Drer\lrp8, Drer\si:dkey-88l16.3, Drer\vldlr, Drer\ldlra, Drer\lrp10, Drer\si:dkey-258f14.3, Drer\lrp3, Drer\lrp12" "Scer\APM3, Scer\APM2, Scer\APM1" "Cele\T13C2.6, Cele\nid-1, Cele\F14B4.1, Cele\lrp-2" "Xtro\lrp8, Xtro\vldlr, Xtro\ldlr" "Mmus\Lrp8, Mmus\Vldlr, Mmus\Lrp3, Mmus\Lrp12, Mmus\Lrp10, Mmus\Ldlr" "Hsap\LDLR, Hsap\LRP12, Hsap\LRP3, Hsap\LRP10, Hsap\LRP8, Hsap\VLDLR" "viable,female fertile,fertile" FBgn0003038 pat patchytergum http://flybase.org/reports/FBgn0003038 - gene - - - pat - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,viable,male,reduced,body color defective" "wing,ocellus,abdominal tergite 5,anterior" FBgn0038361 CG9589 - http://flybase.org/reports/FBgn0038361 protein_coding_gene uroporphyrinogen-III synthase activity ; GO:0004852 | inferred from biological aspect of ancestor with PANTHER:PTN000273374 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000273374 uroporphyrinogen III biosynthetic process ; GO:0006780 | inferred from biological aspect of ancestor with PANTHER:PTN000273374 - "BcDNA:AT11468, CG9589" "IPR003754:Tetrapyrrole biosynthesis, uroporphyrinogen III synthase" CG9589 11-Aug-17 DroID_v2017_08 Drer\uros "Scer\MET1, Scer\HEM4" Cele\Y111B2A.3 Xtro\uros Mmus\Uros Hsap\UROS FBgn0017563 Oef1 oe1 binding factor 1 http://flybase.org/reports/FBgn0017563 - gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "OEF1, Oef1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032780 CG13085 - http://flybase.org/reports/FBgn0032780 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG13085, FBXO3" "IPR032675:Leucine-rich repeat domain, L domain-like" CG13085 11-Aug-17 DroID_v2017_08 - Scer\RCN1 - - - - FBgn0263198 Acn Acinus http://flybase.org/reports/FBgn0263198 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 protein binding ; GO:0005515 | inferred from physical interaction with Aac11 "apoptotic process ; GO:0006915 | inferred from sequence or structural similarity RNA splicing ; GO:0008380 | inferred from mutant phenotype negative regulation of transposition, DNA-mediated ; GO:0000335 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of autophagy ; GO:0010506 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "Acn, hkl, CG10473, l(2)37Ba, Ba, CG10437, dAcn, dacn, Acinus" "IPR034257:Acinus, RNA recognition motif, IPR000504:RNA recognition motif domain, IPR032552:Acin1, RNSP1-SAP18 binding (RSB) motif" CG10473 11-Aug-17 DroID_v2017_08 "Drer\acin1a, Drer\acin1b" Scer\SWR1 Cele\acin-1 "Xtro\acin1, Xtro\rsf1" Mmus\Acin1 "Hsap\ACIN1, Hsap\KIAA0754" DRSC02062 I 1.507061166 1.586493224 0.645977127 0.811754394 -0.649156411 0.121123388 FBgn0002141 l(2)K326 lethal (2) K326 http://flybase.org/reports/FBgn0002141 - gene - - - l(2)K326 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013760 Cbp46A Calmodulin-binding protein 46A http://flybase.org/reports/FBgn0013760 - gene - - - Cbp46A - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage head

FBgn0044342 springer\pol springer element pol http://flybase.org/reports/FBgn0044342 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "ORF2, springer\pol" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028997 nmdyn-D7 nmdyn-D7 http://flybase.org/reports/FBgn0028997 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011410 nucleoside diphosphate kinase activity ; GO:0004550 | inferred from sequence or structural similarity with SGD:S000001550 CTP biosynthetic process ; GO:0006241 | inferred from electronic annotation with InterPro:IPR001564 UTP biosynthetic process ; GO:0006228 | inferred from electronic annotation with InterPro:IPR001564 GTP biosynthetic process ; GO:0006183 | inferred from electronic annotation with InterPro:IPR001564 nucleoside diphosphate phosphorylation ; GO:0006165 | inferred from sequence or structural similarity with SGD:S000001550 nucleoside triphosphate biosynthetic process ; GO:0009142 | inferred from sequence or structural similarity with SGD:S000001550 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000001550 "CG8362, nmdyn-D7" "IPR001564:Nucleoside diphosphate kinase, IPR006602:Uncharacterised domain DM10, IPR011410:Nucleoside diphosphate kinase, NDK7, IPR010554:Domain of unknown function DUF1126" CG8362 11-Aug-17 DroID_v2017_08 "Drer\nme6, Drer\nme4, Drer\nme7, Drer\nme5, Drer\nme2b.1" Scer\YNK1 - "Xtro\nme5, Xtro\nme2, Xtro\nme4, Xtro\nme3, Xtro\nme7, Xtro\nme9, Xtro\nme6" "Mmus\Nme3, Mmus\Nme6, Mmus\Nme4, Mmus\Nme7, Mmus\Nme2, Mmus\Nme1, Mmus\Nme5, Mmus\Nme8" "Hsap\NME3, Hsap\NME8, Hsap\NME7, Hsap\NME5, Hsap\NME1, Hsap\NME6, Hsap\NME2, Hsap\NME4" viable FBgn0263491 ScrPRE Sex-combs-reduced Polycomb group response element http://flybase.org/reports/FBgn0263491 regulatory_region - - - "scrPRE, ScrPRE, Scr PRE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017446 anon-15Da anon-15Da http://flybase.org/reports/FBgn0017446 - gene - - - anon-15Da - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040245 anon-57Bc anon-57Bc http://flybase.org/reports/FBgn0040245 gene - - - anon-57Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019879 anon-69Ad anon-69Ad http://flybase.org/reports/FBgn0019879 - gene - - - anon-69Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage -- adult stage , embryonic stage&&pupal stage " FBgn0264907 CG44098 - http://flybase.org/reports/FBgn0264907 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR011701" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 "CG44098, CG9767, CG12588, CG31530, CG14654" "IPR020846:Major facilitator superfamily domain, IPR011701:Major facilitator superfamily, IPR005828:Major facilitator, sugar transporter-like" CG44098 11-Aug-17 DroID_v2017_08 "Drer\LOC566640, Drer\slc22a6l, Drer\slc22a7b.2, Drer\sv2, Drer\slc22a7b.3, Drer\LOC101884074, Drer\slc22a2, Drer\slc22a13, Drer\si:dkey-166k12.1, Drer\LOC100334012, Drer\slc22a4, Drer\zgc:153639, Drer\slc22a5, Drer\zgc:175176, Drer\zmp:0000001102, Drer\slc22a7b.1, Drer\oatx, Drer\slc22a21" "Scer\YHK8, Scer\TPO1, Scer\DTR1, Scer\AQR1, Scer\HXT2, Scer\QDR1, Scer\TPO3, Scer\HXT9, Scer\FLR1, Scer\QDR2, Scer\GIT1, Scer\QDR3, Scer\PHO84, Scer\TPO2" "Cele\ZK892.3, Cele\T12B3.2, Cele\F23F12.13, Cele\C44C10.3, Cele\oct-2, Cele\Y51A2D.18, Cele\K09E9.1, Cele\T22F7.1, Cele\F17C11.12, Cele\pes-23, Cele\T08B1.1, Cele\C53B4.1, Cele\Y57G11C.23, Cele\F23F12.3, Cele\Y66D12A.13, Cele\F32H5.4" "Xtro\slc22a13, Xtro\slc22a6" "Mmus\Slc22a19, Mmus\Slc22a13, Mmus\Slc22a28, Mmus\Slc22a20, Mmus\Slc22a16, Mmus\Slc22a26, Mmus\Slc22a22, Mmus\Slc22a6, Mmus\Slc22a29, Mmus\Slc22a3, Mmus\Slc22a14, Mmus\Slc22a4, Mmus\Slc22a23, Mmus\Slc22a8, Mmus\Slc22a2, Mmus\Slc22a1, Mmus\Slc22a30, Mmus\Slc22a27, Mmus\Sv2c, Mmus\Slc22a7, Mmus\Svop" "Hsap\SLC22A11, Hsap\SLC22A14, Hsap\SLC22A13, Hsap\SLC22A1, Hsap\SVOP, Hsap\SLC22A3, Hsap\SLC22A23, Hsap\SLC22A7, Hsap\SLC22A6, Hsap\SLC22A9, Hsap\SV2B, Hsap\SLC22A10, Hsap\SLC22A25, Hsap\SV2C, Hsap\SLC22A8, Hsap\SLC22A2, Hsap\SLC22A24, Hsap\SLC22A12" FBgn0038221 CG3259 - http://flybase.org/reports/FBgn0038221 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR018799 molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with MGI:MGI:1921269 intraciliary transport ; GO:0042073 | inferred from biological aspect of ancestor with PANTHER:PTN000773545 cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000773545 cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:1921269 intraciliary transport particle B ; GO:0030992 | inferred from biological aspect of ancestor with PANTHER:PTN000773545 cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN000773545 intraciliary transport particle ; GO:0030990 | inferred from sequence or structural similarity with MGI:MGI:1921269 "CG3259, MIP-T3, IFT54" IPR018799:TRAF3-interacting protein 1 CG3259 11-Aug-17 DroID_v2017_08 Drer\traf3ip1 Scer\USO1 Cele\dyf-11 Xtro\traf3ip1 Mmus\Traf3ip1 Hsap\TRAF3IP1 viable FBgn0004959 phm phantom http://flybase.org/reports/FBgn0004959 "FBgn0000613, FBgn0003080, FBgn0030948" protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 ecdysteroid 25-hydroxylase activity ; GO:0035302 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 ecdysone biosynthetic process ; GO:0006697 | inferred from direct assay ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CYP306A1, phm, Cyp306a1-Dm, exo, Cyp306a1, 306a1, CG6578, ptm, PHM" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG6578 11-Aug-17 DroID_v2017_08 "Drer\cyp17a1, Drer\cyp2aa8, Drer\cyp2y3, Drer\cyp2x12, Drer\cyp2x8, Drer\cyp2n13, Drer\cyp2ae1, Drer\cyp2p7, Drer\cyp2p10, Drer\cyp2ad6, Drer\cyp2k8, Drer\cyp2aa12, Drer\cyp2k18, Drer\cyp1b1, Drer\cyp2k16, Drer\cyp2p8, Drer\si:dkey-286h2.7, Drer\cyp2ad2, Drer\cyp2aa9, Drer\cyp2p9, Drer\cyp1a, Drer\cyp2x10.2, Drer\cyp2u1, Drer\cyp2k17, Drer\cyp1c2, Drer\cyp17a2, Drer\cyp2aa11, Drer\cyp2k19, Drer\cyp2k6, Drer\cyp2aa3, Drer\cyp2k22, Drer\si:zfos-411a11.2, Drer\cyp2k20, Drer\cyp2j20, Drer\cyp2k31, Drer\cyp2ad3, Drer\cyp2aa4, Drer\cyp2aa1, Drer\cyp1d1, Drer\cyp2p6, Drer\cyp2aa2, Drer\cyp21a2, Drer\cyp2k21, Drer\cyp2r1, Drer\cyp2x7, Drer\cyp2v1, Drer\LOC100148115, Drer\cyp1c1, Drer\cyp2x9, Drer\cyp2x6" - "Cele\cyp-23A1, Cele\cyp-33C3, Cele\cyp-35B2, Cele\cyp-33C7, Cele\cyp-36A1, Cele\daf-9, Cele\cyp-34A7, Cele\cyp-34A9, Cele\cyp-34A5, Cele\cyp-35A3, Cele\cyp-33E2, Cele\cyp-34A8, Cele\cyp-33C4, Cele\cyp-34A2, Cele\cyp-34A4, Cele\cyp-35A1, Cele\cyp-34A6, Cele\cyp-35A5, Cele\cyp-33C5, Cele\cyp-33D1, Cele\cyp-35A2, Cele\cyp-33A1, Cele\cyp-35B1, Cele\cyp-33C12, Cele\cyp-33B1, Cele\cyp-33C11, Cele\cyp-33C9, Cele\cyp-33D3, Cele\cyp-35B3, Cele\cyp-33C6, Cele\cyp-35D1, Cele\cyp-33C8, Cele\cyp-34A10, Cele\cyp-33E1, Cele\cyp-33C1, Cele\cyp-33C2, Cele\cyp-35A4, Cele\cyp-35C1, Cele\cyp-34A1" "Xtro\MGC69416, Xtro\cyp17a1, Xtro\cyp2r1, Xtro\cyp2e1, Xtro\cyp1a1, Xtro\LOC100493194, Xtro\cyp2b6, Xtro\MGC107969, Xtro\cyp2c8.2, Xtro\cyp2j2, Xtro\LOC619584, Xtro\cyp2a13, Xtro\cyp1b1, Xtro\cyp2g1p, Xtro\LOC100145084, Xtro\cyp2f2, Xtro\cyp2c8.1, Xtro\LOC100486127, Xtro\MGC69353, Xtro\cyp2a6, Xtro\cyp2d6, Xtro\LOC100145323, Xtro\LOC100497184, Xtro\LOC100145541, Xtro\LOC100145695, Xtro\cyp1d1, Xtro\LOC100497460, Xtro\cyp2u1, Xtro\LOC100036663, Xtro\LOC548374, Xtro\cyp21a2.1, Xtro\cyp2w1" "Mmus\Cyp2c55, Mmus\Cyp2c67, Mmus\Cyp2a5, Mmus\Cyp2a12, Mmus\Cyp2c65, Mmus\Cyp2a4, Mmus\Cyp2r1, Mmus\Cyp2g1, Mmus\Cyp2c69, Mmus\Cyp2f2, Mmus\Cyp2b19, Mmus\Cyp2j8, Mmus\Cyp2a22, Mmus\Cyp2c37, Mmus\Cyp1b1, Mmus\Cyp2c54, Mmus\Cyp2j9, Mmus\Cyp2j13, Mmus\Cyp2c39, Mmus\Cyp2d12, Mmus\Cyp2j5, Mmus\Cyp2c66, Mmus\Cyp17a1, Mmus\Cyp1a2, Mmus\Cyp2b23, Mmus\Cyp2w1, Mmus\Cyp2b10, Mmus\Cyp2e1, Mmus\Cyp2d40, Mmus\Cyp2u1, Mmus\Cyp2d26, Mmus\Cyp2d9, Mmus\Cyp2d11, Mmus\Cyp2c50, Mmus\Cyp2j6, Mmus\Cyp2d34, Mmus\Cyp2j11, Mmus\Cyp2d22, Mmus\Cyp2j12, Mmus\Cyp2c40, Mmus\Cyp2d10, Mmus\Cyp2s1, Mmus\Cyp2c68, Mmus\Cyp1a1, Mmus\Cyp2c70, Mmus\Cyp2ab1, Mmus\Cyp2c44, Mmus\Cyp2b9, Mmus\Cyp2c29, Mmus\Cyp2c38, Mmus\Cyp2b13, Mmus\Cyp21a1, Mmus\Cyp2t4" "Hsap\CYP2A13, Hsap\CYP2R1, Hsap\CYP2C19, Hsap\CYP1A2, Hsap\CYP2D6, Hsap\CYP2A7, Hsap\CYP21A2, Hsap\CYP2W1, Hsap\CYP2C9, Hsap\CYP1B1, Hsap\CYP2A6, Hsap\CYP2J2, Hsap\CYP2E1, Hsap\CYP2C8, Hsap\CYP2S1, Hsap\CYP2C18, Hsap\CYP17A1, Hsap\CYP1A1, Hsap\CYP2B6, Hsap\CYP2F1, Hsap\CYP2U1" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,maternal effect,circadian rhythm defective,viable,visible,body color defective" "ovary,embryonic/first instar larval cuticle,embryonic head,embryonic/larval hindgut,presumptive embryonic/larval central nervous system,commissure,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,stage 14 embryo,dorsal closure embryo,presumptive embryonic/larval digestive system,midgut primordium,embryo,border follicle cell,somatic clone,embryonic/larval cuticle,chaeta,supernumerary,mesothoracic tergum" DRSC20237 IE 0.445341058 2.506769234 1.613821022 -0.659958986 -1.36520105 0.655688151 FBgn0029605 CG18082 - http://flybase.org/reports/FBgn0029605 protein_coding_gene - - - CG18082 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266891 CR45351 - http://flybase.org/reports/FBgn0266891 non_protein_coding_gene - - - CR45351 - CR45351 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038366 CG4576 - http://flybase.org/reports/FBgn0038366 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG4576 IPR002656:Acyltransferase 3 CG4576 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-5, Cele\oac-53, Cele\oac-3, Cele\oac-7, Cele\oac-20, Cele\oac-6, Cele\oac-9, Cele\nrf-6, Cele\oac-31, Cele\oac-39, Cele\oac-55, Cele\rhy-1, Cele\oac-32, Cele\oac-54, Cele\oac-14, Cele\oac-50, Cele\ndg-4, Cele\oac-46" - Mmus\Oacyl - viable FBgn0065501 l(2)SH1207 lethal (2) SH1207 http://flybase.org/reports/FBgn0065501 gene - - - "l(2)SH1207, l(2)SH2 1207" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020809 mei-1916 mei-1916 http://flybase.org/reports/FBgn0020809 - gene - - - mei-1916 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086387 BG01686 - http://flybase.org/reports/FBgn0086387 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01686 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0082928 snoRNA:Me28S-G3255a snoRNA:Me28S-G3255a http://flybase.org/reports/FBgn0082928 snoRNA_gene - - - "snoRNA:Me28S-G3255a, Me28S-Gm3255a, Me28S-G3255a(DmSnR48), CR34526, DmSnR48a" - CR34526 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015533 rack on-the-rack http://flybase.org/reports/FBgn0015533 - gene - peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement - rack - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,some die during immature adult stage" "presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral" FBgn0263473 snoRNA:abba-a - http://flybase.org/reports/FBgn0263473 snoRNA_gene - - - snoRNA:abba-a - CR43588 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004668 Bsg99D Blastoderm-specific transcript 99D http://flybase.org/reports/FBgn0004668 - gene - - - Bsg99D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266691 CR45181 - http://flybase.org/reports/FBgn0266691 non_protein_coding_gene - - - CR45181 - CR45181 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267792 rgr regular http://flybase.org/reports/FBgn0267792 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence model" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence model" nucleus ; GO:0005634 | inferred from sequence model "rgr, l(2)k02605, CG8643, CG14751" "IPR013087:Zinc finger C2H2-type, IPR006578:MADF domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8643 11-Aug-17 DroID_v2017_08 "Drer\LOC101883230, Drer\LOC799968, Drer\si:dkey-261j4.5, Drer\si:ch73-40a17.4, Drer\si:dkey-261j4.4, Drer\LOC560148, Drer\si:ch211-222k6.2, Drer\zgc:113886, Drer\si:ch211-241b2.4, Drer\drl, Drer\si:ch211-108m2.2, Drer\zgc:171673, Drer\znf1178, Drer\si:dkey-34m19.3, Drer\znf1003, Drer\LOC103911016, Drer\LOC100537317, Drer\im:7141269, Drer\LOC100330167, Drer\si:dkey-262g12.3, Drer\si:ch211-276c2.4, Drer\LOC100333031, Drer\wu:fe17e08, Drer\LOC108179164, Drer\LOC101883594, Drer\zbtb24, Drer\zgc:165514, Drer\si:ch73-299h12.9, Drer\si:ch211-198a12.6, Drer\LOC103909987, Drer\si:ch211-155e24.3, Drer\si:dkey-261j4.3, Drer\LOC100538142, Drer\zgc:112998" Scer\AZF1 "Cele\sdz-12, Cele\che-1, Cele\Y56A3A.28, Cele\scrt-1" - "Mmus\Zfp853, Mmus\Zfp637, Mmus\Zfp995, Mmus\Gm13212, Mmus\Zbtb24, Mmus\Zfp980, Mmus\Zfp691" "Hsap\ZNF853, Hsap\ZNF711, Hsap\ZNF85, Hsap\ZNF32, Hsap\ZNF691" FBgn0029097 anon-89Ec anon-89Ec http://flybase.org/reports/FBgn0029097 gene - - - "III, anon-89Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030320 CG2247 - http://flybase.org/reports/FBgn0030320 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model defense response to bacterium ; GO:0042742 | inferred from mutant phenotype SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model nucleus ; GO:0005634 | inferred from direct assay "CG2247, FBXL5" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001810:F-box domain" CG2247 11-Aug-17 DroID_v2017_08 "Drer\fbxo41, Drer\si:ch73-290k24.5, Drer\znf365" - - - "Mmus\Fbxo41, Mmus\Zfp365" "Hsap\ZNF365, Hsap\FBXO41" "viable,fertile" FBgn0065708 l(2)SH0609 lethal (2) SH0609 http://flybase.org/reports/FBgn0065708 gene - - - "l(2)SH0609, l(2)SH2 0609" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267306 CR45742 - http://flybase.org/reports/FBgn0267306 non_protein_coding_gene - - - CR45742 - CR45742 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267951 CR46231 - http://flybase.org/reports/FBgn0267951 non_protein_coding_gene - - - "CR46231, lincRNA.497" - CR46231 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052085 CG32085 - http://flybase.org/reports/FBgn0052085 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG6060, CT33735, CG14134, BcDNA:RH06780, CG32085, FBXL16" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR006553:Leucine-rich repeat, cysteine-containing subtype, IPR001611:Leucine-rich repeat" CG32085 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-192l18.9, Drer\fbxl16" "Scer\GRR1, Scer\RAD7" - Xtro\fbxl16 "Mmus\Fbxl17, Mmus\Fbxl16" Hsap\FBXL16 viable FBgn0028377 gdl-ORF39 gdl-ORF39 http://flybase.org/reports/FBgn0028377 protein_coding_gene - - - "CG7268, ORF39, CG33088, CG33755, gdl-ORF39" - CG33755 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267707 CR46040 - http://flybase.org/reports/FBgn0267707 non_protein_coding_gene - - - CR46040 - CR46040 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001767 l(1)M36 lethal (1) M36 http://flybase.org/reports/FBgn0001767 - gene - - - l(1)M36 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0031343 CG18131 - http://flybase.org/reports/FBgn0031343 protein_coding_gene - - - "BcDNA:AT12853, CG18131" - CG18131 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0002756 mit(1)6 mitotic 6 http://flybase.org/reports/FBgn0002756 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0039690 CG1969 - http://flybase.org/reports/FBgn0039690 protein_coding_gene glucosamine 6-phosphate N-acetyltransferase activity ; GO:0004343 | inferred from biological aspect of ancestor with PANTHER:PTN000331679 UDP-N-acetylglucosamine biosynthetic process ; GO:0006048 | inferred from biological aspect of ancestor with PANTHER:PTN000331679 - CG1969 "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG1969 11-Aug-17 DroID_v2017_08 Drer\gnpnat1 Scer\GNA1 "Cele\gna-1, Cele\gna-2" Xtro\gnpnat1 Mmus\Gnpnat1 Hsap\GNPNAT1 viable FBgn0053469 CG33469 - http://flybase.org/reports/FBgn0053469 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33469 - CG33469 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067772 fragile-locus-D fragile locus D http://flybase.org/reports/FBgn0067772 gene molecular_function ; GO:0003674 | no biological data available egg activation ; GO:0007343 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fragile-locus-D - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" FBgn0053544 Vkor Vitamin-K epoxide reductase http://flybase.org/reports/FBgn0053544 protein_coding_gene vitamin-K-epoxide reductase (warfarin-sensitive) activity ; GO:0047057 | inferred from sequence or structural similarity with HGNC:21492 vitamin-K-epoxide reductase (warfarin-sensitive) activity ; GO:0047057 | inferred from sequence or structural similarity with HGNC:23663 vitamin K metabolic process ; GO:0042373 | inferred from sequence or structural similarity with HGNC:21492 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with HGNC:21492 "BP1071, VKORC1, HDC06808, CG33544, Vkor" IPR012932:Vitamin K epoxide reductase CG33544 11-Aug-17 DroID_v2017_08 "Drer\vkorc1, Drer\vkorc1l1" - - "Xtro\vkorc1, Xtro\vkorc1l1" "Mmus\Vkorc1l1, Mmus\Prss53, Mmus\Vkorc1" "Hsap\VKORC1L1, Hsap\VKORC1" viable FBgn0262170 CG42878 - http://flybase.org/reports/FBgn0262170 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42878, chr2R_15474834_15475129.0" "IPR002919:Trypsin Inhibitor-like, cysteine rich domain" CG42878 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039110 RanBP3 Ran binding protein 3 http://flybase.org/reports/FBgn0039110 protein_coding_gene GTPase activator activity ; GO:0005096 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000566604 Ran GTPase binding ; GO:0008536 | inferred from biological aspect of ancestor with PANTHER:PTN000566730 G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from direct assay RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 spindle organization ; GO:0007051 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 positive regulation of mitotic centrosome separation ; GO:0046604 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 nuclear export ; GO:0051168 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 protein export from nucleus ; GO:0006611 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 "RanBP3, GC10225, CG10225" "IPR000156:Ran binding domain, IPR011993:PH domain-like" CG10225 11-Aug-17 DroID_v2017_08 "Drer\ranbp3a, Drer\ranbp3b" "Scer\NUP2, Scer\YRB1, Scer\YRB2" Cele\ran-5 Xtro\ranbp3 "Mmus\Ranbp3, Mmus\Ranbp3l" "Hsap\RANBP3, Hsap\RANBP3L" "viable,fertile" FBgn0067903 IM18 Immune induced molecule 18 http://flybase.org/reports/FBgn0067903 protein_coding_gene - response to bacterium ; GO:0009617 | inferred from expression pattern defense response to other organism ; GO:0098542 | inferred from mutant phenotype defense response ; GO:0006952 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "DIM 18, BcDNA:AT19986, CG33706, anon-WO0153538.58, anon-WO0153538.57, anon-WO0153538.56, IM18" - CG33706 11-Aug-17 DroID_v2017_08 - - - - - - "immune response defective,short lived,conditional" FBgn0036405 CG6833 - http://flybase.org/reports/FBgn0036405 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 - - CG6833 "IPR012337:Ribonuclease H-like domain, IPR013520:Exonuclease, RNase T/DNA polymerase III" CG6833 11-Aug-17 DroID_v2017_08 "Drer\rexo4, Drer\isg20, Drer\isg20l2" Scer\REX4 "Cele\C05C8.5, Cele\Y47G6A.30, Cele\Y17G7B.12" "Xtro\rexo4, Xtro\aen, Xtro\LOC100158551" "Mmus\Isg20l2, Mmus\2610020H08Rik, Mmus\Aen, Mmus\Isg20, Mmus\Rexo4" "Hsap\AEN, Hsap\REXO4, Hsap\ISG20, Hsap\ISG20L2" "viable,fertile" FBgn0062927 CR32735 - http://flybase.org/reports/FBgn0062927 non_protein_coding_gene - - - "BcDNA:RH57246, CR32735" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037710 CG9393 - http://flybase.org/reports/FBgn0037710 protein_coding_gene - protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q13505 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:Q13505 mitochondrial outer membrane ; GO:0005741 | inferred from direct assay CG9393 "IPR017410:Mitochondrial outer membrane transport complex protein, metaxin, IPR019564:Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain, IPR010987:Glutathione S-transferase, C-terminal-like, IPR033468:Metaxin, glutathione S-transferase domain" CG9393 11-Aug-17 DroID_v2017_08 "Drer\mtx1a, Drer\mtx3, Drer\mtx1b, Drer\mtx2" Scer\SAM37 "Cele\mtx-1, Cele\mtx-2" "Xtro\mtx3, Xtro\mtx1, Xtro\mtx2" "Mmus\Mtx1, Mmus\Mtx2, Mmus\Mtx3" "Hsap\MTX2, Hsap\MTX1, Hsap\MTX3" "viable,fertile" FBgn0266840 CR45302 - http://flybase.org/reports/FBgn0266840 non_protein_coding_gene - - - CR45302 - CR45302 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065475 l(2)SH1311 lethal (2) SH1311 http://flybase.org/reports/FBgn0065475 gene - - - l(2)SH1311 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005707 l(1)TK110 lethal (1) TK110 http://flybase.org/reports/FBgn0005707 - gene - - - "l110, l(1)TK110" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0264527 ff20 - http://flybase.org/reports/FBgn0264527 gene - - - ff20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" FBgn0039385 CG5913 - http://flybase.org/reports/FBgn0039385 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:26773 biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:26773 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:26773 tRNA-splicing ligase complex ; GO:0072669 | inferred from biological aspect of ancestor with PANTHER:PTN001263924 CG5913 IPR018797:Uncharacterised protein family FAM98 CG5913 11-Aug-17 DroID_v2017_08 "Drer\fam98a, Drer\im:7138535, Drer\fam98b" - Cele\tag-322 "Xtro\fam98b, Xtro\fam98a" "Mmus\Spred3, Mmus\Fam98a, Mmus\Fam98c, Mmus\Fam98b" "Hsap\FAM98B, Hsap\FAM98C, Hsap\FAM98A" "lethal,partially lethal - majority die,visible" trichogen cell FBgn0265752 CR44559 - http://flybase.org/reports/FBgn0265752 non_protein_coding_gene - - - "CR44559, lincRNA.545" - CR44559 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262028 CR42839 - http://flybase.org/reports/FBgn0262028 non_protein_coding_gene - - - CR42839 - CR42839 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085779 CR40963 - http://flybase.org/reports/FBgn0085779 rRNA_gene - - - CR40963 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029851 CG14445 - http://flybase.org/reports/FBgn0029851 protein_coding_gene - - - CG14445 - CG14445 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032176 CG13127 - http://flybase.org/reports/FBgn0032176 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13127 "IPR031936:Domain of unknown function DUF4771, IPR031935:Domain of unknown function DUF4770" CG13127 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0029977 hdm hold'em http://flybase.org/reports/FBgn0029977 protein_coding_gene single-stranded DNA binding ; GO:0003697 | inferred from sequence model single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN001465761 single-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008310 | inferred from biological aspect of ancestor with PANTHER:PTN001465761 protein binding ; GO:0005515 | inferred from physical interaction with mei-9 inferred from physical interaction with Ercc1 nucleic acid phosphodiester bond hydrolysis ; GO:0090305 | inferred from biological aspect of ancestor with PANTHER:PTN001465761 oocyte fate determination ; GO:0030716 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype resolution of meiotic recombination intermediates ; GO:0000712 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from physical interaction with mei-9 inferred from physical interaction with Ercc1 "CG15329, hdm" "IPR012340:Nucleic acid-binding, OB-fold" CG15329 11-Aug-17 DroID_v2017_08 - - Cele\rpa-1 Xtro\meiob Mmus\Meiob Hsap\MEIOB "meiotic cell cycle defective,viable" presumptive oocyte FBgn0052726 CG32726 - http://flybase.org/reports/FBgn0052726 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RH59280, CG32726" - CG32726 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040864 CG15755 - http://flybase.org/reports/FBgn0040864 protein_coding_gene - - - CG15755 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265989 trp::trpl - http://flybase.org/reports/FBgn0265989 engineered_fusion_gene - - - trp::trpl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065484 l(2)SH1269 lethal (2) SH1269 http://flybase.org/reports/FBgn0065484 gene - - - "l(2)SH1269, l(2)SH2 1269" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264694 mgr merry-go-round http://flybase.org/reports/FBgn0264694 protein_coding_gene beta-tubulin binding ; GO:0048487 | inferred from direct assay protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR016655 spindle assembly involved in meiosis ; GO:0090306 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from mutant phenotype establishment or maintenance of neuroblast polarity ; GO:0045196 | inferred from mutant phenotype tubulin complex assembly ; GO:0007021 | inferred from biological aspect of ancestor with PANTHER:PTN000274575 prefoldin complex ; GO:0016272 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay prefoldin complex ; GO:0016272 | colocalizes_with inferred from direct assay polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN000274575 "mgr, CG6719, BcDNA:LD34406, PAC10, Pfdn3, Mgr" "IPR004127:Prefoldin alpha-like, IPR016655:Prefoldin subunit 3" CG6719 11-Aug-17 DroID_v2017_08 Drer\vbp1 Scer\PAC10 Cele\pfd-3 Xtro\vbp1 Mmus\Vbp1 Hsap\VBP1 FBgn0069430 JJF004 JJF004 http://flybase.org/reports/FBgn0069430 gene - - - JJF004 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0259827 ifm(2)RS11 indirect flight muscle (2) RS11 http://flybase.org/reports/FBgn0259827 gene - adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS11 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable indirect flight muscle FBgn0038106 CG7488 - http://flybase.org/reports/FBgn0038106 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006073, InterPro:IPR030388" - microtubule associated complex ; GO:0005875 | inferred from direct assay CG7488 "IPR030388:Era-type guanine nucleotide-binding (G) domain, IPR015946:K homology domain-like, alpha/beta, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR005225:Small GTP-binding protein domain, IPR006073:GTP binding domain" CG7488 11-Aug-17 DroID_v2017_08 Drer\eral1 - Cele\E02H1.2 Xtro\eral1 Mmus\Eral1 Hsap\ERAL1 "lethal,recessive" DRSC16250 K 0.537515372 0.938453102 0.166807554 0.104460585 -1.600181908 -0.813039694 FBgn0031451 CG9961 - http://flybase.org/reports/FBgn0031451 protein_coding_gene phosphoglycerate kinase activity ; GO:0004618 | inferred from sequence or structural similarity with SGD:S000000605 glycolytic process ; GO:0006096 | inferred from sequence or structural similarity with SGD:S000000605 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000605 CG9961 "IPR001576:Phosphoglycerate kinase, IPR015824:Phosphoglycerate kinase, N-terminal, IPR015911:Phosphoglycerate kinase, conserved site" CG9961 11-Aug-17 DroID_v2017_08 Drer\pgk1 Scer\PGK1 Cele\pgk-1 Xtro\pgk1 "Mmus\Pgk2, Mmus\Pgk1" "Hsap\PGK1, Hsap\PGK2" viable FBgn0038377 CG9632 - http://flybase.org/reports/FBgn0038377 protein_coding_gene - - - "bs19g07.y1, NEST:bs19g07, BcDNA:AT06908, CG9632" - CG9632 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0050215 tRNA:Ile-AAT-1-9 transfer RNA:Isoleucine-AAT 1-9 http://flybase.org/reports/FBgn0050215 tRNA_gene AUU codon-amino acid adaptor activity ; GO:0033433 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033433 cytosol ; GO:0005829 | inferred by curator from GO:0033433 "AE002787.trna53-IleAAT, tRNA:I:AAT:AE002787-h, CR30215, chr2R.trna36-IleAAT, tRNA-Ile[AAU], tRNA-Ile-AAT-1-9, tRNA:Ile-AAT-1-9, tRNA:CR30215, AUU" - CR30215 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020509 Acp62F Accessory gland protein 62F http://flybase.org/reports/FBgn0020509 - protein_coding_gene peptidase inhibitor activity ; GO:0030414 | traceable author statement serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from direct assay serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from sequence or structural similarity negative regulation of proteolysis ; GO:0045861 | inferred from sequence or structural similarity regulation of proteolysis ; GO:0030162 | traceable author statement negative regulation of proteolysis ; GO:0045861 | traceable author statement multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of proteolysis ; GO:0045861 | inferred from direct assay sperm competition ; GO:0046692 | inferred from mutant phenotype negative regulation of proteolysis ; GO:0045861 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "Acp62F, CT2528, CG1262, Acp62, Acp62f" "IPR002919:Trypsin Inhibitor-like, cysteine rich domain" CG1262 11-Aug-17 DroID_v2017_08 - - "Cele\C10G8.4, Cele\F32D8.3, Cele\swm-1, Cele\B0238.12, Cele\T01D3.3, Cele\C25E10.8, Cele\K07A1.6, Cele\F53C11.9, Cele\C53B7.2, Cele\C25E10.7, Cele\Y26D4A.12, Cele\spi-1" - - - "lethal,heat sensitive,viable" FBgn0082946 snoRNA:Me28S-A2634a snoRNA:Me28S-A2634a http://flybase.org/reports/FBgn0082946 snoRNA_gene - - - "snoRNA:Me28S-A2634a, Me28S-Am2634a, Me28S-A2634a, CR34636" - CR34636 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051591 tRNA:Val-AAC-1-2 transfer RNA:Valine-AAC 1-2 http://flybase.org/reports/FBgn0051591 tRNA_gene GUU codon-amino acid adaptor activity ; GO:0033449 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033449 cytosol ; GO:0005829 | inferred by curator from GO:0033449 "AE002708.trna47-ValAAC, valine tRNA, tRNA-Val-4, Val-tRNA-4, val-tRNA-4, tRNA[Val][[4]], tRNA:val4:90Cb, tRNA:val4:90Ca, tRNA:V:AAC:AE002708-b, tRNA:V4:90Cb, tRNA:V4:90Ca, tRNA:V4, tRNA:-?:90Cc, CR31591, tRNA[Val-AAC], chr3R.trna53-ValAAC, tRNA:Val-AAC-1-2, tRNA:V4:90C, tRNA-Val-AAC-1-2, GUU" - CR31591 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040339 MED22 Mediator complex subunit 22 http://flybase.org/reports/FBgn0040339 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from electronic annotation with InterPro:IPR009332 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 inferred from physical interaction with UniProtKB:Q9VEC1 RNA polymerase II transcription cofactor activity ; GO:0001104 | contributes_to inferred by curator from GO:0016592 regulation of transcription from RNA polymerase II promoter involved in spermatogenesis ; GO:1902064 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred by curator from GO:0016592 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay "144358_at, Med22, Med24, CG18830, Srb6/Surf5, dMED24, EG:BACR7A4.6, CG3034, clone 1.82, anon-EST:Liang-1.82, MED22, med22" IPR009332:Mediator of RNA polymerase II transcription subunit 22 CG3034 11-Aug-17 DroID_v2017_08 Drer\med22 - Cele\mdt-22 Xtro\med22 Mmus\Med22 Hsap\MED22 DRSC18175 K -1.092840123 0.592541785 -0.52931813 1.149291411 0.615923301 2.25475101 FBgn0037073 Tsr1 Tsr1 ribosome assembly factor http://flybase.org/reports/FBgn0037073 protein_coding_gene GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000304594 U3 snoRNA binding ; GO:0034511 | inferred from biological aspect of ancestor with PANTHER:PTN000304594 GTP binding ; GO:0005525 | inferred from biological aspect of ancestor with PANTHER:PTN000304594 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000304594 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype ribosome assembly ; GO:0042255 | inferred from sequence or structural similarity with UniProtKB:Q08965 positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000479 | inferred from biological aspect of ancestor with PANTHER:PTN000304594" "nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q08965 preribosome, small subunit precursor ; GO:0030688 | inferred from biological aspect of ancestor with PANTHER:PTN000304671" "CG7338, Tsr1" "IPR007034:Ribosome biogenesis protein BMS1/TSR1, C-terminal, IPR012948:AARP2CN, IPR030387:Bms1/Tsr1-type G domain, IPR011989:Armadillo-like helical" CG7338 11-Aug-17 DroID_v2017_08 Drer\tsr1 Scer\TSR1 Cele\tag-151 - Mmus\Tsr1 Hsap\TSR1 "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0016906 l(3)X12 lethal (3) X12 http://flybase.org/reports/FBgn0016906 - gene - - - "X12, l(3)X12" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012037 Ance Angiotensin converting enzyme http://flybase.org/reports/FBgn0012037 "FBgn0014013, FBgn0025190" protein_coding_gene metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR001548 peptidyl-dipeptidase activity ; GO:0008241 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay sperm individualization ; GO:0007291 | inferred from mutant phenotype spermatid nucleus differentiation ; GO:0007289 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from expression pattern response to symbiotic bacterium ; GO:0009609 | inferred from expression pattern inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001548 extracellular space ; GO:0005615 | inferred from direct assay "Race, ance, race, CG8827, ACE, AnCE, RACE, BG:DS08220.3, l(2)34Eb, l34Eb, br31, l(2)br31, anon-EST:fe3D10, Ance, ANCE" "IPR001548:Peptidase M2, peptidyl-dipeptidase A" CG8827 11-Aug-17 DroID_v2017_08 "Drer\ace2, Drer\ace, Drer\si:dkey-194e6.1" - Cele\acn-1 "Xtro\tmem27, Xtro\ace, Xtro\ace2" "Mmus\Ace, Mmus\Tmem27, Mmus\Ace2, Mmus\Ace3" "Hsap\TMEM27, Hsap\ACE, Hsap\ACE2" " embryonic stage | stage >9 , embryonic stage | late , embryonic stage | 4-12 hr , embryonic stage | stage 5-13 , embryonic stage -- adult stage " " posterior embryonic/larval midgut

, anterior embryonic/larval midgut

, pericardial cell

, amnioserosa

, embryonic/larval dorsal vessel

" "wild-type,lethal,recessive,partially lethal - majority live,male sterile,viable" "testis,spermatid,spermatid & nucleusAdh-nBR55),primary spermatocyte cyst,major mitochondrial derivativeAdh-nBR55),minor mitochondrial derivativeAdh-nBR55)" FBgn0003148 pre presto http://flybase.org/reports/FBgn0003148 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available pre - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0015770 MstProx MstProx http://flybase.org/reports/FBgn0015770 - protein_coding_gene single-stranded RNA binding ; GO:0003727 | inferred from electronic annotation with InterPro:IPR026880 transmembrane signaling receptor activity ; GO:0004888 | inferred from electronic annotation with InterPro:IPR026880 MyD88-dependent toll-like receptor signaling pathway ; GO:0002755 | inferred from electronic annotation with InterPro:IPR026880 defense response to virus ; GO:0051607 | inferred from electronic annotation with InterPro:IPR026880 toll-like receptor 7 signaling pathway ; GO:0034154 | inferred from electronic annotation with InterPro:IPR026880 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR026880 "dToll3, Toll-3, toll, dTLR3, mstprox, Tl-3, CG1149, DmMstProx, MstProx, Mstprox" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR000372:Leucine-rich repeat N-terminal domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR026880:Toll-like receptor 7" CG1149 11-Aug-17 DroID_v2017_08 "Drer\tlr21, Drer\LOC100332783, Drer\cd180, Drer\tlr4ba, Drer\LOC572462, Drer\tlr3, Drer\tlr5b, Drer\tlr20.2, Drer\zgc:101569, Drer\tlr2, Drer\tlr4bb, Drer\LOC100332583, Drer\tlr9, Drer\tlr5a, Drer\LOC100005571, Drer\tlr18, Drer\tlr8b, Drer\tlr1, Drer\tlr7" - Cele\tol-1 "Xtro\tlr3, Xtro\LOC100485512, Xtro\LOC100495326, Xtro\LOC100485164, Xtro\tlr9, Xtro\LOC100485201, Xtro\tlr2, Xtro\tlr6, Xtro\tlr5, Xtro\tlr7, Xtro\LOC100485706" "Mmus\Tlr7, Mmus\Tlr8, Mmus\Tlr1, Mmus\Tlr9, Mmus\Tlr3, Mmus\Tlr6, Mmus\Tlr11, Mmus\Tlr4, Mmus\Tlr2, Mmus\Cd180, Mmus\Tlr5, Mmus\Tlr12, Mmus\Tlr13" "Hsap\TLR1, Hsap\TLR2, Hsap\TLR3, Hsap\TLR4, Hsap\CD180, Hsap\TLR5, Hsap\TLR10, Hsap\TLR9, Hsap\TLR7, Hsap\TLR8, Hsap\TLR6" "viable,lethal" FBgn0085806 CR41585 - http://flybase.org/reports/FBgn0085806 non_protein_coding_gene - - - CR41585 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030949 Cyp308a1 Cyp308a1 http://flybase.org/reports/FBgn0030949 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "308a1, CG6585, Cyp308a1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG6585 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp3c1, Drer\cyp3c2, Drer\cyp3c4, Drer\cyp3c3, Drer\tbxas1" "Scer\ERG11, Scer\DIT2" "Cele\cyp-13B1, Cele\cyp-25A4, Cele\cyp-13A10, Cele\cyp-13A11, Cele\cyp-13A8, Cele\cyp-13A12, Cele\cyp-44A1, Cele\cyp-25A1, Cele\cyp-13A1, Cele\cyp-13A6, Cele\cyp-13A4, Cele\cyp-13A2, Cele\cyp-25A3, Cele\cyp-13A5, Cele\cyp-13A3, Cele\cyp-13A7, Cele\cyp-43A1, Cele\cyp-25A2, Cele\cyp-13B2" "Xtro\tbxas1, Xtro\LOC100494419, Xtro\cyp3a4, Xtro\cyp3a5" "Mmus\Cyp3a25, Mmus\Cyp3a59, Mmus\Cyp3a16, Mmus\Cyp3a41b, Mmus\Cyp3a11, Mmus\Cyp3a57, Mmus\Cyp3a41a, Mmus\Tbxas1, Mmus\Cyp3a13, Mmus\Cyp3a44" "Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A43, Hsap\CYP3A4, Hsap\CYP3A7, Hsap\TBXAS1, Hsap\CYP3A5" viable FBgn0260308 GSd233 - http://flybase.org/reports/FBgn0260308 gene - - - GSd233 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective" FBgn0001997 l(2)36Aa lethal (2) 36Aa http://flybase.org/reports/FBgn0001997 - gene - - - "l(2L)HT-5, l(2)HT-5, l(2)36Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065064 snoRNA:Psi28S-291 - http://flybase.org/reports/FBgn0065064 snoRNA_gene - - - "Dm-50, snoR50, CR33754, Psi28s-291 snoRNA, psi28s-291, snoRNA:Psi28S-291, Psi 28S-291(SnoR50), snoRNA:50, Psi28S-291, chr3R:7049275..7049407" - CR33754 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030918 CG15056 - http://flybase.org/reports/FBgn0030918 protein_coding_gene - - - CG15056 "IPR032675:Leucine-rich repeat domain, L domain-like" CG15056 11-Aug-17 DroID_v2017_08 "Drer\zgc:158376, Drer\fbxl4, Drer\fbxl15, Drer\fbxl17, Drer\kdm2aa, Drer\kdm2ab, Drer\si:dkey-192l18.9, Drer\fbxl6" Scer\GRR1 Cele\EEED8.10 "Xtro\fbxl4, Xtro\kdm2b, Xtro\fbxl19, Xtro\fbxl12" "Mmus\Fbxl19, Mmus\Kdm2a, Mmus\Fbxl4, Mmus\Kdm2b, Mmus\Lrrc29, Mmus\Fbxl21, Mmus\Fbxl17, Mmus\Fbxl6" "Hsap\FBXL17, Hsap\FBXL19, Hsap\FBXL13, Hsap\KDM2A, Hsap\FBXL6, Hsap\KDM2B, Hsap\FBXL4, Hsap\LRRC29" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0259420 C436 - http://flybase.org/reports/FBgn0259420 gene - - - C436 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing" FBgn0005292 mei-2220 meiotic 2220 http://flybase.org/reports/FBgn0005292 - gene - - - "2220, mei-2220" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0083936 Acp54A1 Accessory gland protein 54A1 http://flybase.org/reports/FBgn0083936 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CG34098, Acp54A1" - CG34098 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028246 l(3)S000107 lethal (3) S000107 http://flybase.org/reports/FBgn0028246 gene - - - "1118/16, 1118/02, 0263/09, 0251/32, 0122/24, 0082/23, 0661/21, 0232/04, 0194/18, 0143/27, 0001/07, l(3)S111816, l(3)S111802, l(3)S026309, l(3)S025132, l(3)S012224, l(3)S008223, l(3)S000107" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0040515 CG17445 - http://flybase.org/reports/FBgn0040515 protein_coding_gene - - - CG17445 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004817 fs(2)ltoAHK35 female sterile (2) ltoAHK35 http://flybase.org/reports/FBgn0004817 - gene molecular_function ; GO:0003674 | no biological data available ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoAHK35 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0259923 Sep4 Septin 4 http://flybase.org/reports/FBgn0259923 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR016491, InterPro:IPR030379 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with pnut" mitotic cytokinesis ; GO:0000281 | inferred from sequence or structural similarity septin ring ; GO:0005940 | inferred from sequence or structural similarity "CG9699, Sep4, sep4, dSEPT4" "IPR030379:Septin-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR016491:Septin" CG9699 11-Aug-17 DroID_v2017_08 "Drer\zgc:162239, Drer\sept8b, Drer\sept6, Drer\sept5a, Drer\sept3, Drer\sept4a, Drer\sept10, Drer\sept7a, Drer\sept12, Drer\sept15, Drer\sept2, Drer\zgc:63587, Drer\sept5b, Drer\sept7b, Drer\sept4b, Drer\sept8a" "Scer\CDC10, Scer\SPR3, Scer\CDC11, Scer\SPR28, Scer\SHS1, Scer\CDC3, Scer\CDC12" "Cele\unc-59, Cele\unc-61" "Xtro\sept7, Xtro\sept8, Xtro\sept6, Xtro\sept2, Xtro\sept11, Xtro\sept10, Xtro\sept5" "Mmus\Sept5, Mmus\Sept14, Mmus\Sept2, Mmus\Sept9, Mmus\Sept6, Mmus\Sept1, Mmus\Sept10, Mmus\Sept7, Mmus\Sept11, Mmus\Sept4, Mmus\Sept12, Mmus\Sept3, Mmus\Sept8" "Hsap\SEPT8, Hsap\SEPT10, Hsap\SEPT12, Hsap\SEPT5, Hsap\SEPT9, Hsap\SEPT7, Hsap\SEPT4, Hsap\SEPT11, Hsap\SEPT2, Hsap\SEPT1, Hsap\C9orf69, Hsap\SEPT14, Hsap\SEPT6, Hsap\SEPT3" FBgn0030576 CG15890 - http://flybase.org/reports/FBgn0030576 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG15890 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG15890 11-Aug-17 DroID_v2017_08 "Drer\slc46a1, Drer\slc46a3, Drer\si:ch211-262i1.4, Drer\zgc:174356, Drer\hiat1a, Drer\hiat1b, Drer\si:dkey-5g14.1, Drer\LOC557306, Drer\LOC100002406" Scer\YJL163C "Cele\Y43F8A.5, Cele\C46C11.2, Cele\Y4C6B.5, Cele\F40F9.5" "Xtro\slc46a1, Xtro\slc46a3, Xtro\slc46a2, Xtro\mfsd14b, Xtro\mfsd14a" "Mmus\Mfsd14a, Mmus\Mfsd14b, Mmus\Slc46a2, Mmus\Slc46a1, Mmus\Slc46a3" "Hsap\SLC46A2, Hsap\MFSD14B, Hsap\SLC46A1, Hsap\MFSD14A, Hsap\SLC46A3" "viable,fertile" FBgn0265956 CR44743 - http://flybase.org/reports/FBgn0265956 non_protein_coding_gene - - - "lincRNA.44, CR44743" - CR44743 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035903 CG6765 - http://flybase.org/reports/FBgn0035903 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 CG6765 "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG6765 11-Aug-17 DroID_v2017_08 - - - - - Hsap\ZBTB9 "viable,fertile" FBgn0029532 CG13361 - http://flybase.org/reports/FBgn0029532 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13361 - CG13361 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037188 CG7369 - http://flybase.org/reports/FBgn0037188 protein_coding_gene Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | inferred from sequence or structural similarity with HGNC:24246 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from sequence or structural similarity with HGNC:24246 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG7369 "IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR023578:Ras guanine nucleotide exchange factor domain, IPR019804:Ras guanine-nucleotide exchange factor, conserved site" CG7369 11-Aug-17 DroID_v2017_08 "Drer\rasgef1bb, Drer\rasgef1ba" Scer\CDC25 Cele\R05G6.10 "Xtro\rasgef1b, Xtro\rasgef1a" "Mmus\Rasgef1a, Mmus\Rasgef1b, Mmus\Rasgef1c" "Hsap\RASGEF1C, Hsap\RASGEF1B, Hsap\RASGEF1A" FBgn0023028 l(2)CA5 lethal (2) CA5 http://flybase.org/reports/FBgn0023028 - gene - - - l(2)CA5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265168 CR44237 - http://flybase.org/reports/FBgn0265168 non_protein_coding_gene - - - CR44237 - CR44237 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065288 l(2)SH2018 lethal (2) SH2018 http://flybase.org/reports/FBgn0065288 gene - - - "l(2)SH2018, l(2)SH2 2018" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263649 CR43640 - http://flybase.org/reports/FBgn0263649 non_protein_coding_gene - - - CR43640 - CR43640 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061013 l(3)S026020b lethal (3) S026020b http://flybase.org/reports/FBgn0061013 gene - - - "0260/20, l(3)S026020b" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060791 l(3)S058712b lethal (3) S058712b http://flybase.org/reports/FBgn0060791 gene - - - "0587/12, l(3)S058712b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016643 ER2-7B ER2-7B http://flybase.org/reports/FBgn0016643 - gene - - - ER2-7B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026760 Tehao Tehao http://flybase.org/reports/FBgn0026760 - protein_coding_gene protein kinase binding ; GO:0019901 | inferred from physical interaction with pll Toll binding ; GO:0005121 | inferred from physical interaction with Tl coreceptor activity ; GO:0015026 | inferred from direct assay positive regulation of antifungal peptide biosynthetic process ; GO:0006967 | traceable author statement innate immune response ; GO:0045087 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from direct assay positive regulation of antimicrobial peptide biosynthetic process ; GO:0002807 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | traceable author statement - "dToll5, Toll 5, Toll-5, toll, dTLR5, tehao, Tl-5, CT22017, CG7121, Tehao, Tho" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5" CG7121 11-Aug-17 DroID_v2017_08 "Drer\tlr21, Drer\tlr4bb, Drer\dnaaf1, Drer\tlr18, Drer\zgc:101569, Drer\tlr5b, Drer\tlr4ba, Drer\tlr1, Drer\LOC100005571, Drer\LOC100332783, Drer\LOC572462, Drer\tlr5a, Drer\LOC100332583, Drer\tlr8b, Drer\tlr9, Drer\tlr2, Drer\tlr3, Drer\tlr19, Drer\cd180, Drer\tlr20.2, Drer\tlr7" - - "Xtro\LOC100485706, Xtro\LOC100485201, Xtro\LOC100485512, Xtro\LOC100495326, Xtro\tlr2, Xtro\tlr9, Xtro\tlr7, Xtro\tlr5, Xtro\tlr3, Xtro\tlr6, Xtro\LOC100485164" "Mmus\Tlr11, Mmus\Tlr3, Mmus\Tlr7, Mmus\Cd180, Mmus\Dnaaf1, Mmus\Tlr5, Mmus\Il1rapl2, Mmus\Tlr6, Mmus\Tlr1, Mmus\Tlr2, Mmus\Tlr9, Mmus\Tlr8, Mmus\Tlr4, Mmus\Tlr13, Mmus\Tlr12" "Hsap\IL1RAPL2, Hsap\TLR8, Hsap\TLR6, Hsap\TLR3, Hsap\DNAAF1, Hsap\TLR2, Hsap\TLR10, Hsap\TLR5, Hsap\CD180, Hsap\TLR9, Hsap\TLR4, Hsap\TLR7, Hsap\TLR1" larval stage&&adult stage "behavior defective,recessive,viable,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,tormogen cell" FBgn0015335 anon-100Ab anon-100Ab http://flybase.org/reports/FBgn0015335 - gene - - - "T2, anon-100Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031758 Ucp4B Uncoupling protein 4B http://flybase.org/reports/FBgn0031758 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 oxidative phosphorylation uncoupler activity ; GO:0017077 | inferred from sequence or structural similarity with UniProtKB:O95847 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:O95847 response to cold ; GO:0009409 | inferred from biological aspect of ancestor with PANTHER:PTN001942541 regulation of mitochondrial membrane potential ; GO:0051881 | inferred from biological aspect of ancestor with PANTHER:PTN001942541 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:O95847 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG18340, dmUCP4b, DmUCP4B, Ucp4B, Ucp 4b, Ucp4b, UCP4B, ucp4B" "IPR018108:Mitochondrial substrate/solute carrier, IPR002030:Mitochondrial brown fat uncoupling protein, IPR023395:Mitochondrial carrier domain" CG18340 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-100f3.2, Drer\ucp2, Drer\ucp3, Drer\ucp1, Drer\slc25a11, Drer\slc25a14, Drer\slc25a10, Drer\mrpl12, Drer\slc25a27" Scer\DIC1 "Cele\mrpl-12, Cele\slc-25A10, Cele\ucp-4" "Xtro\ucp1, Xtro\slc25a27, Xtro\rangrf, Xtro\ucp2, Xtro\slc25a10, Xtro\slc25a30" "Mmus\Ucp3, Mmus\Slc25a27, Mmus\Slc25a10, Mmus\Ucp2, Mmus\Slc25a14, Mmus\Ucp1, Mmus\Slc25a30, Mmus\Slc25a11, Mmus\Mrpl12" "Hsap\UCP1, Hsap\SLC25A14, Hsap\SLC25A27, Hsap\UCP3, Hsap\MRPL12, Hsap\SLC25A10, Hsap\SLC25A11, Hsap\SLC25A30, Hsap\UCP2" "viable,visible" trichogen cell FBgn0019665 p71 p71 http://flybase.org/reports/FBgn0019665 - gene - - - p71 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004095 l(2)60Dc lethal (2) 60Dc http://flybase.org/reports/FBgn0004095 FBgn0016891 gene - - - "l(2)B485, l(2)60Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034308 CG10915 - http://flybase.org/reports/FBgn0034308 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10915 "IPR019131:Cortactin-binding protein-2, N-terminal" CG10915 11-Aug-17 DroID_v2017_08 "Drer\ppp1r16a, Drer\fam184a, Drer\cttnbp2, Drer\filip1l, Drer\LOC101884302, Drer\cttnbp2nla, Drer\luzp1, Drer\cttnbp2nlb" Scer\YCR051W "Cele\C49H3.6, Cele\F34D10.6, Cele\gfi-2" "Xtro\filip1, Xtro\cttnbp2nl, Xtro\ppp1r16b, Xtro\cttnbp2, Xtro\luzp1" "Mmus\Ppp1r16b, Mmus\Filip1, Mmus\Ppp1r16a, Mmus\Cttnbp2, Mmus\Cttnbp2nl, Mmus\Luzp1, Mmus\Filip1l" "Hsap\PPP1R16B, Hsap\FILIP1, Hsap\LUZP1, Hsap\FILIP1L, Hsap\CTTNBP2, Hsap\PPP1R16A, Hsap\CTTNBP2NL" viable DRSC06469 K 1.470382858 -0.814945888 0.493387698 -1.187506264 1.158883908 1.749323853 FBgn0024591 l(2)k02705 lethal (2) k02705 http://flybase.org/reports/FBgn0024591 - gene - - - "27/5, l(2)k02705" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013236 E(var)190 E(var)190 http://flybase.org/reports/FBgn0013236 - gene - - - E(var)190 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0044425 M80-39 M80-39 http://flybase.org/reports/FBgn0044425 gene molecular_function ; GO:0003674 | no biological data available establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "M80#A39, M80#39, M80-39" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye photoreceptor cell,somatic clone,eye equator,cell non-autonomous,ectopic" FBgn0058365 CG40365 - http://flybase.org/reports/FBgn0058365 protein_coding_gene - - - CG40365 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267265 CR45701 - http://flybase.org/reports/FBgn0267265 non_protein_coding_gene - - - CR45701 - CR45701 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030753 rngo rings lost http://flybase.org/reports/FBgn0030753 protein_coding_gene "aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001995, InterPro:IPR019103 proteasome binding ; GO:0070628 | inferred from physical interaction with Rpn10 ubiquitin binding ; GO:0043130 | inferred from direct assay" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001995, InterPro:IPR019103 female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG4420, rngo" "IPR000626:Ubiquitin domain, IPR001995:Peptidase A2A, retrovirus, catalytic, IPR009060:UBA-like, IPR015940:Ubiquitin-associated domain, IPR033882:DNA damage inducible protein 1 ubiquitin-like domain, IPR008920:Transcription regulator FadR/GntR, C-terminal, IPR029071:Ubiquitin-related domain, IPR021109:Aspartic peptidase domain, IPR019103:Aspartic peptidase, DDI1-type" CG4420 11-Aug-17 DroID_v2017_08 "Drer\ddi2, Drer\nrip2" Scer\DDI1 Cele\ddi-1 "Xtro\ddi2, Xtro\nrip3" "Mmus\Nrip3, Mmus\Nrip2, Mmus\Ddi1, Mmus\Ddi2, Mmus\Rsc1a1" "Hsap\DDI1, Hsap\DDI2, Hsap\NRIP3, Hsap\RSC1A1, Hsap\NRIP2" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,partially lethal - majority die" "female germline ring canal | germline clone,oocyte nucleus,germline clone" FBgn0013654 ms(2)ry1 ms(2)ry1 http://flybase.org/reports/FBgn0013654 - gene - - - ms(2)ry1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female fertile,poor,male sterile" FBgn0260435 CR42530 - http://flybase.org/reports/FBgn0260435 pseudogene_attribute - - - CR42530 - CR42530 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263910 l(3)C79 - http://flybase.org/reports/FBgn0263910 gene - - - l(3)C79 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0034135 Syn2 Syntrophin-like 2 http://flybase.org/reports/FBgn0034135 protein_coding_gene structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC:13740 inferred from sequence or structural similarity with HGNC:13741 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity rhabdomere development ; GO:0042052 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from genetic interaction with Nsf2 syntrophin complex ; GO:0016013 | inferred from sequence or structural similarity with HGNC:13740 inferred from sequence or structural similarity with HGNC:13741 syntrophin complex ; GO:0016013 | inferred from sequence or structural similarity "CG4905, DmSYN-2, Syn2" "IPR001478:PDZ domain, IPR015482:Syntrophin, IPR011993:PH domain-like" CG4905 11-Aug-17 DroID_v2017_08 "Drer\sntg1, Drer\sntg2" - Cele\stn-2 Xtro\sntg1 "Mmus\Sntg1, Mmus\Sntg2" "Hsap\SNTG2, Hsap\SNTG1" "viable,locomotor behavior defective,increased cell death" "eye,ommatidium,ocellar bristle,rhabdomereGMR.PS,mesothoracic tergum" FBgn0031726 Cyp6a16 Cyp6a16 http://flybase.org/reports/FBgn0031726 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002402 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002402 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002402 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002402, InterPro:IPR017972" - "6a16, Cyp6a16p, CG7249, CR7249, Cyp6a16, Cyp6a16Psi" "IPR001128:Cytochrome P450, IPR017972:Cytochrome P450, conserved site, IPR002402:Cytochrome P450, E-class, group II" CG7249 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\tbxas1, Drer\cyp3c2, Drer\cyp3c3, Drer\cyp3c4, Drer\cyp3c1" - "Cele\cyp-25A2, Cele\cyp-13A11, Cele\cyp-13A12, Cele\cyp-43A1, Cele\cyp-25A1, Cele\cyp-13B1, Cele\cyp-25A6, Cele\cyp-25A4, Cele\cyp-13A8, Cele\cyp-25A3, Cele\cyp-13B2, Cele\cyp-13A6, Cele\cyp-44A1, Cele\cyp-13A5, Cele\cyp-13A3, Cele\cyp-13A1, Cele\cyp-13A10, Cele\cyp-13A2, Cele\cyp-13A4, Cele\cyp-13A7" "Xtro\LOC100494419, Xtro\cyp3a4, Xtro\cyp3a5, Xtro\tbxas1" "Mmus\Cyp3a41b, Mmus\Tbxas1, Mmus\Cyp3a44, Mmus\Cyp3a41a, Mmus\Cyp3a16, Mmus\Cyp3a59, Mmus\Cyp3a57, Mmus\Cyp3a25, Mmus\Cyp3a13" "Hsap\CYP3A5, Hsap\CYP3A4, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A43, Hsap\TBXAS1" FBgn0037035 CG10589 - http://flybase.org/reports/FBgn0037035 protein_coding_gene - - - "anon-WO0140519.139, CG10589" IPR032013:Protein of unknown function DUF4795 CG10589 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060499 l(3)S106810 lethal (3) S106810 http://flybase.org/reports/FBgn0060499 gene - - - "1068/10, l(3)S106810" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037140 SLC22A SLC22A family member http://flybase.org/reports/FBgn0037140 protein_coding_gene choline transmembrane transporter activity ; GO:0015220 | inferred from direct assay organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 acetylcholine transport ; GO:0015870 | inferred from direct assay regulation of synaptic transmission, cholinergic ; GO:0032222 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 "CG7442, SLC22A, DmSLC22A" "IPR020846:Major facilitator superfamily domain, IPR005828:Major facilitator, sugar transporter-like" CG7442 11-Aug-17 DroID_v2017_08 "Drer\slc22a4, Drer\slc22a21, Drer\slc22a5, Drer\slc22a7b.1, Drer\zmp:0000001102, Drer\slc22a7a, Drer\slc22a7b.3" "Scer\GIT1, Scer\HXT2, Scer\HXT9, Scer\PHO84" "Cele\ZK892.3, Cele\T22F7.1, Cele\Y82E9BR.16, Cele\oct-1, Cele\svop-1, Cele\C53B4.1, Cele\Y57G11C.23, Cele\oct-2, Cele\Y51A2D.18, Cele\C46C2.2, Cele\Y66D12A.13" "Xtro\slc22a5, Xtro\slc22a4" "Mmus\Svop, Mmus\Slc22a21, Mmus\Slc22a4, Mmus\Slc22a5" "Hsap\SLC22A4, Hsap\SLC22A5, Hsap\SVOP" viable FBgn0037662 CG11997 - http://flybase.org/reports/FBgn0037662 protein_coding_gene - - - CG11997 - CG11997 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067068 N9 N9 http://flybase.org/reports/FBgn0067068 gene - - - N9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective,lethal,partially lethal - majority die" "chaeta,pigment cell" FBgn0083005 snoRNA:Psi28S-1175a snoRNA:Psi28S-1175a http://flybase.org/reports/FBgn0083005 snoRNA_gene - - - "snoRNA:Psi28S-1175a, psi28s-1175a, Psi 28S-1175a, CR34558" - CR34558 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038714 Cpr92A Cuticular protein 92A http://flybase.org/reports/FBgn0038714 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr92A, CG6240, DmelCpr92A" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG6240 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266950 CR45401 - http://flybase.org/reports/FBgn0266950 non_protein_coding_gene - - - CR45401 - CR45401 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033491 CG18011 - http://flybase.org/reports/FBgn0033491 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG17847, CG18011" "IPR017900:4Fe-4S ferredoxin, iron-sulphur binding, conserved site, IPR013087:Zinc finger C2H2-type" CG18011 11-Aug-17 DroID_v2017_08 "Drer\zgc:113119, Drer\si:ch211-216l23.1, Drer\zgc:172128, Drer\znf592, Drer\znf687a, Drer\znf451" Scer\RME1 "Cele\sdz-12, Cele\pag-3, Cele\Y48G8AL.10" "Xtro\znf451, Xtro\znf423" "Mmus\Zfp451, Mmus\Zfp423, Mmus\Zfp521" "Hsap\ZNF521, Hsap\ZNF423, Hsap\ZNF343, Hsap\ZNF451, Hsap\ZNF133" "partially lethal - majority die,some die during pupal stage" DRSC06706 I 1.602422265 0.591233627 1.073054019 -0.335849208 0.800112607 0.055312256 FBgn0065387 l(2)SH1635 lethal (2) SH1635 http://flybase.org/reports/FBgn0065387 gene - - - "l(2)SH1635, l(2)SH2 1635" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060571 l(3)S095814b lethal (3) S095814b http://flybase.org/reports/FBgn0060571 gene - - - "0958/14, l(3)S095814b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053241 Ste:CG33241 Ste:CG33241 http://flybase.org/reports/FBgn0053241 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG32605, CG33241, Ste:CG33241" "IPR016149:Casein kinase II, regulatory subunit, alpha-helical, IPR000704:Casein kinase II, regulatory subunit" CG33241 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0086254 CG6084 - http://flybase.org/reports/FBgn0086254 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG6084, 34F4T, ESTS:34F4T" "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG6084 11-Aug-17 DroID_v2017_08 "Drer\akr1a1b, Drer\akr1a1a, Drer\zgc:101765, Drer\zgc:110782, Drer\zgc:110366, Drer\akr1b1, Drer\si:dkey-180p18.9, Drer\zgc:56622" "Scer\GRE3, Scer\GCY1, Scer\YJR096W, Scer\YPR1, Scer\YDL124W, Scer\ARA1" "Cele\F53F1.3, Cele\Y39G8B.1, Cele\Y39G8B.2, Cele\C56G3.2, Cele\F53F1.2, Cele\C35D10.6, Cele\K07C5.2, Cele\ZK1290.5, Cele\C07D8.6, Cele\C01G5.5, Cele\T08H10.1, Cele\ZC443.1" "Xtro\akr1c1, Xtro\akr1b1, Xtro\akr1c8p, Xtro\akr1a1, Xtro\akr1d1, Xtro\akr1c2, Xtro\LOC548351" "Mmus\Akr1c14, Mmus\Akr1cl, Mmus\Akr1a1, Mmus\Akr1c13, Mmus\Akr1c18, Mmus\Akr1b8, Mmus\Akr1e1, Mmus\Akr1d1, Mmus\Akr1c6, Mmus\Akr1c21, Mmus\Akr1c12, Mmus\Akr1b10, Mmus\Akr1b7, Mmus\Akr1c20, Mmus\Akr1b3, Mmus\Akr1c19" "Hsap\AKR1C3, Hsap\AKR1C4, Hsap\AKR1A1, Hsap\AKR1D1, Hsap\AKR1C1, Hsap\AKR1E2, Hsap\AKR1C2, Hsap\AKR1B1, Hsap\AKR1B10, Hsap\AKR1B15" FBgn0066057 amz amazon http://flybase.org/reports/FBgn0066057 gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available amz - - 11-Aug-17 DroID_v2017_08 - - - - - - "increased cell size,somatic clone,neuroanatomy defective" "embryonic/larval mushroom body,somatic clone" FBgn0267135 CR45575 - http://flybase.org/reports/FBgn0267135 non_protein_coding_gene - - - "lincRNA.730, CR45575" - CR45575 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260085 2L3696 - http://flybase.org/reports/FBgn0260085 gene - - - 2L3696 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0011944 tRNA:Pro-TGG-1-1 transfer RNA:Proline-TGG 1-1 http://flybase.org/reports/FBgn0011944 "FBgn0003819, FBgn0051567, FBgn0060110" tRNA_gene CCA codon-amino acid adaptor activity ; GO:0033423 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033423 cytosol ; GO:0005829 | inferred by curator from GO:0033423 "Pro, AE002708.trna51-ProTGG, tRNA:P:TGG:AE002708-e, tRNA:pro:90Ca, CR31567, tRNA:Pro, chr3R.trna57-ProTGG, tRNA-Pro-TGG-1-1, tRNA:Pro-TGG-1-1, tRNA:P:90Ca, CCA" - CR31567 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030029 CG15343 - http://flybase.org/reports/FBgn0030029 protein_coding_gene "FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR011576, InterPro:IPR012349 pyridoxamine-phosphate oxidase activity ; GO:0004733 | inferred from biological aspect of ancestor with PANTHER:PTN000852047" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000659, InterPro:IPR011576, InterPro:IPR012349 pyridoxine biosynthetic process ; GO:0008615 | inferred from electronic annotation with InterPro:IPR000659 pyridoxal phosphate biosynthetic process ; GO:0042823 | inferred from biological aspect of ancestor with PANTHER:PTN000852047" - CG15343 "IPR000659:Pyridoxamine 5'-phosphate oxidase, IPR011576:Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain, IPR012349:FMN-binding split barrel" CG15343 11-Aug-17 DroID_v2017_08 Drer\pnpo Scer\PDX3 Cele\F57B9.1 Xtro\pnpo Mmus\Pnpo Hsap\PNPO viable FBgn0027229 l(1)G0296 lethal (1) G0296 http://flybase.org/reports/FBgn0027229 - gene - - - l(1)G0296 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0035240 CG33791 - http://flybase.org/reports/FBgn0035240 protein_coding_gene thiamine pyrophosphate binding ; GO:0030976 | inferred from electronic annotation with InterPro:IPR011603 oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591 | inferred from biological aspect of ancestor with PANTHER:PTN000568211 oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591 | inferred from sequence or structural similarity with UniProtKB:Q02218 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000568211 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:Q02218 oxoglutarate dehydrogenase complex ; GO:0045252 | inferred from biological aspect of ancestor with PANTHER:PTN000568211 mitochondrial oxoglutarate dehydrogenase complex ; GO:0009353 | inferred from sequence or structural similarity with UniProtKB:Q02218 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000568260 "CG13918, CG7934, CG32316, CG32316-ORFB, CG33791, OGDH" "IPR001017:Dehydrogenase, E1 component, IPR005475:Transketolase-like, pyrimidine-binding domain, IPR011603:2-oxoglutarate dehydrogenase E1 component, IPR029061:Thiamin diphosphate-binding fold, IPR032106:2-oxoglutarate dehydrogenase E1 component, N-terminal domain, IPR031717:Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal" CG33791 11-Aug-17 DroID_v2017_08 "Drer\dhtkd1, Drer\ogdhb, Drer\ogdhl, Drer\ogdha" Scer\KGD1 "Cele\ZK836.2, Cele\ogdh-1" "Xtro\ogdh, Xtro\ogdhl, Xtro\dhtkd1" "Mmus\Ogdh, Mmus\Ogdhl, Mmus\Dhtkd1" "Hsap\OGDHL, Hsap\OGDH, Hsap\DHTKD1" DRSC08601 K -0.463705424 0.506691879 -0.417293371 0.088433317 1.593121282 0.200828548 FBgn0051685 CG31685 - http://flybase.org/reports/FBgn0051685 protein_coding_gene - - - CG31685 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051144 CR31144 - http://flybase.org/reports/FBgn0051144 non_protein_coding_gene - - - CR31144 - CR31144 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260595 2L2828 - http://flybase.org/reports/FBgn0260595 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2828 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0015859 anon-14Ac anon-14Ac http://flybase.org/reports/FBgn0015859 - gene - - - "td39, anon-14Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023097 bon bonus http://flybase.org/reports/FBgn0023097 "FBgn0038812, FBgn0038813, FBgn0060905, FBgn0062022" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR001841, InterPro:IPR001965 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:11812 zinc ion binding ; GO:0008270 | inferred from sequence model chromatin binding ; GO:0003682 | inferred from direct assay" chromatin organization ; GO:0006325 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:11812 nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "150269_at, 150268_at, CG5206, Bonus, 0434/20, 0487/06, 0249/12, 0241/08, l(3)S043420, CG15687, anon-WO0118547.418, bon, Bon" "IPR000315:B-box-type zinc finger, IPR001487:Bromodomain, IPR001841:Zinc finger, RING-type, IPR001965:Zinc finger, PHD-type, IPR003649:B-box, C-terminal, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5206 11-Aug-17 DroID_v2017_08 "Drer\trim24, Drer\trim25l, Drer\trim33l, Drer\trim33, Drer\trim35-1, Drer\trim66, Drer\aire" - - "Xtro\trim33, Xtro\trim28, Xtro\trim24" "Mmus\Trim66, Mmus\Trim28, Mmus\Trim24, Mmus\Aire, Mmus\Trim33" "Hsap\TRIM33, Hsap\TRIM28, Hsap\TRIM24, Hsap\TRIM66, Hsap\AIRE" "visible,suppressor of variegation,dominant,body color defective,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,male,viable,female,reduced,lethal - all die before end of first instar larval stage,some die during first instar larval stage,female limited,partially lethal - majority die,male limited,cell lethalcell lethal,somatic clone,increased cell death,enhancer of variegation" "eye,interommatidial bristle,ommatidium,wing,pupal abdomen & cuticle,abdominal tergite & macrochaeta,abdominal sternite bristle,wing margin bristle,neuron,head,embryonic/larval salivary gland,female,photoreceptor cell,somatic clone,adult head & cuticle | somatic clone,embryonic/larval tracheal system" DRSC16914 E -0.140195436 -0.740743091 -1.553476033 0.469098939 0.605946637 0.097094107 FBgn0266432 CG45062 - http://flybase.org/reports/FBgn0266432 protein_coding_gene "nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR008250, InterPro:IPR023299 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250" - - "CG45062, CG3701, alphalike" "IPR023298:P-type ATPase, transmembrane domain, IPR008250:P-type ATPase, A domain, IPR023214:HAD-like domain, IPR006068:Cation-transporting P-type ATPase, C-terminal, IPR023299:P-type ATPase, cytoplasmic domain N" CG45062 11-Aug-17 DroID_v2017_08 "Drer\atp2a2b, Drer\atp2a1l, Drer\atp2a2a, Drer\si:dkey-28b4.8, Drer\atp2a3, Drer\atp2a1" Scer\PMR1 "Cele\catp-3, Cele\sca-1, Cele\catp-1, Cele\catp-2" - "Mmus\Atp2a1, Mmus\Atp2a2, Mmus\Atp2a3" "Hsap\ATP2A2, Hsap\ATP2A1, Hsap\ATP2A3" FBgn0038452 CG14905 - http://flybase.org/reports/FBgn0038452 protein_coding_gene - cilium movement ; GO:0003341 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 outer dynein arm assembly ; GO:0036158 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 outer dynein arm ; GO:0036157 | inferred from electronic annotation with InterPro:IPR029652 axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 CG14905 IPR029652:ODA1/DCC2 family CG14905 11-Aug-17 DroID_v2017_08 Drer\ccdc114 - - Xtro\ccdc63 "Mmus\Ccdc63, Mmus\Ccdc114" "Hsap\CCDC114, Hsap\CCDC63" viable FBgn0266587 CR45112 - http://flybase.org/reports/FBgn0266587 non_protein_coding_gene - - - CR45112 - CR45112 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261401 Ir75c Ionotropic receptor 75c http://flybase.org/reports/FBgn0261401 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir75c, IR75c, DmelIR75c, CG14586-A, CG14586, CG42642, IR75abc" IPR001320:Ionotropic glutamate receptor CG42642 11-Aug-17 DroID_v2017_08 "Drer\grid1a, Drer\LOC100537813, Drer\grid1b" - Cele\W02A2.5 - "Mmus\Grid1, Mmus\Grik4" Hsap\GRID1 FBgn0267043 CG45487 - http://flybase.org/reports/FBgn0267043 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45487 - CG45487 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037122 CG14570 - http://flybase.org/reports/FBgn0037122 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14570 IPR032011:Domain of unknown function DUF4794 CG14570 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037408 NPFR Neuropeptide F receptor http://flybase.org/reports/FBgn0037408 protein_coding_gene neuropeptide Y receptor activity ; GO:0004983 | inferred from electronic annotation with InterPro:IPR000611 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model neuropeptide F receptor activity ; GO:0042263 | inferred from physical interaction with NPF tachykinin receptor activity ; GO:0004995 | inferred from sequence or structural similarity tachykinin receptor activity ; GO:0004995 | inferred from sequence or structural similarity with RYa-R negative regulation of adenylate cyclase activity ; GO:0007194 | inferred from direct assay tachykinin receptor signaling pathway ; GO:0007217 | inferred from sequence or structural similarity with RYa-R G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model larval feeding behavior ; GO:0030536 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with RYa-R integral component of plasma membrane ; GO:0005887 | inferred from direct assay "CG1147, npfr1, NPFR, dNPFR1, anon-WO0131005.5, anon-WO0131005.3, NPFR1, RE18294p, DmNPFR1, NPFR-1, NPFr, NPF-R, Drm-NPFR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000611:Neuropeptide Y receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG1147 11-Aug-17 DroID_v2017_08 "Drer\npy1r, Drer\npy8br, Drer\npy4r, Drer\npy7r, Drer\npy8ar, Drer\npy2rl, Drer\npy2r, Drer\npffr2a" - "Cele\npr-1, Cele\npr-22, Cele\npr-5, Cele\npr-12, Cele\npr-8, Cele\npr-11, Cele\npr-2, Cele\npr-4" "Xtro\npy2r, Xtro\qrfpr, Xtro\npy5r" "Mmus\Npffr2, Mmus\Npy6r, Mmus\Npy2r, Mmus\Qrfpr, Mmus\Npy1r, Mmus\Npy4r, Mmus\Npy5r" "Hsap\CH17-360D5.1, Hsap\LOC105379861, Hsap\NPY4R, Hsap\NPY5R, Hsap\NPFFR2, Hsap\NPY1R, Hsap\NPY2R, Hsap\QRFPR" "viable,fertile,memory defective,feeding behavior defective,chemical resistant,behavior defective,male" FBgn0066307 Bari2\ORF Bari2 element ORF http://flybase.org/reports/FBgn0066307 transposable_element_gene - - - Bari2\ORF - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262648 l(2)47A3 lethal (2) 47A3 http://flybase.org/reports/FBgn0262648 gene - - - l(2)47A3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062644 EP646 EP646 http://flybase.org/reports/FBgn0062644 gene - - - "EP(2)0646, EP646" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019896 anon-2Ba anon-2Ba http://flybase.org/reports/FBgn0019896 - gene - - - anon-2Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034774 CG13526 - http://flybase.org/reports/FBgn0034774 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "BcDNA:AT13807, CG13526, CBP8" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG13526 11-Aug-17 DroID_v2017_08 "Drer\calml4a, Drer\rhbdl3, Drer\calm2b, Drer\tnnc2, Drer\caln1, Drer\calm3b, Drer\pvalb8, Drer\cetn4, Drer\calb2b, Drer\cabp5b, Drer\cabp2a, Drer\scgn, Drer\calb1, Drer\tnnc1a, Drer\calb2a, Drer\pvalb1, Drer\pvalb6, Drer\efcab11, Drer\calm3a, Drer\si:ch211-197n1.2, Drer\pvalb3, Drer\pvalb9, Drer\cabp5a, Drer\cabp7b, Drer\efcab2, Drer\pvalb2, Drer\calml4b, Drer\pvalb4, Drer\efcab6, Drer\tnnc1b, Drer\cabp1a, Drer\caln2, Drer\calm1a, Drer\calm1b, Drer\calm2a" "Scer\MLC2, Scer\CDC31, Scer\MLC1, Scer\CMD1" "Cele\cal-8, Cele\R08D7.5, Cele\cal-7" "Xtro\ocm, Xtro\scgn, Xtro\pvalb.1, Xtro\efcab6, Xtro\ocm.2, Xtro\calml4, Xtro\LOC548651, Xtro\calb1, Xtro\cabp7, Xtro\calm1, Xtro\cabp4, Xtro\tnnc2, Xtro\tnnc1, Xtro\pgm1, Xtro\pvalb.2, Xtro\calm2, Xtro\pvalb" "Mmus\Pvalb, Mmus\Cabp4, Mmus\Efcab11, Mmus\1700023F06Rik, Mmus\Cetn2, Mmus\Cabp7, Mmus\Calb2, Mmus\Efhd1, Mmus\Caln1, Mmus\Efcab9, Mmus\Efcab2, Mmus\Spata21, Mmus\Tnnc1, Mmus\Rhbdl3, Mmus\Cabp1, Mmus\Efcab7, Mmus\Efcab3, Mmus\Efcab6, Mmus\Tnnc2, Mmus\Calml3, Mmus\Calml4, Mmus\Calb1, Mmus\Cabp2, Mmus\Ocm, Mmus\Calm3, Mmus\Calm4, Mmus\Calm2, Mmus\Scgn, Mmus\Calm1, Mmus\Cabp5" "Hsap\CALML6, Hsap\OCM2, Hsap\PVALB, Hsap\EFCAB11, Hsap\TNNC2, Hsap\CABP2, Hsap\OCM, Hsap\CALML5, Hsap\EFCAB7, Hsap\EFCAB13, Hsap\EFHD1, Hsap\SCGN, Hsap\CABP4, Hsap\CABP5, Hsap\CALM2, Hsap\CALM3, Hsap\CETN2, Hsap\EFCAB6, Hsap\CABP1, Hsap\CABP7, Hsap\SPATA21, Hsap\EFCAB9, Hsap\CALML4, Hsap\TNNC1, Hsap\RHBDL3, Hsap\CALML3, Hsap\CALB1, Hsap\EFCAB3, Hsap\CALN1, Hsap\CALM1, Hsap\CALB2, Hsap\EFCAB2" viable FBgn0041124 l(2)45Am lethal (2) 45Am http://flybase.org/reports/FBgn0041124 gene - - - l(2)45Am - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0037885 CG17721 - http://flybase.org/reports/FBgn0037885 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN000967717 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000967717 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001820464 "CG17721, BcDNA:LP09251" "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17721 11-Aug-17 DroID_v2017_08 Drer\ttc3 - "Cele\Y105C5B.11, Cele\C09E7.5" - Mmus\Ttc3 Hsap\TTC3 viable FBgn0069406 JJF237 JJF237 http://flybase.org/reports/FBgn0069406 gene - - - JJF237 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0065548 l(2)SH1044 lethal (2) SH1044 http://flybase.org/reports/FBgn0065548 gene - - - "l(2)SH1044, l(2)SH2 1044" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011143 l(1)Q219 lethal (1) Q219 http://flybase.org/reports/FBgn0011143 FBgn0010210 gene - - - l(1)Q219 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0042154 CG18831 - http://flybase.org/reports/FBgn0042154 protein_coding_gene - - - CG18831 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026177 skn skinhead http://flybase.org/reports/FBgn0026177 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available skn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000216 Brd Bearded http://flybase.org/reports/FBgn0000216 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with neur cell fate specification ; GO:0001708 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | traceable author statement sensory organ development ; GO:0007423 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype - "CG3096, Brd, Brd-C, brd, DmelCG3096" - CG3096 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | third instar , embryonic stage | 4-8hr , prepupal stage | stage P4 " " morphogenetic furrow | vicinity of

, proneural cluster

, eye disc

, imaginal disc

, sensillum campaniformium &&of wing

, external sensory organ precursor cell

, morphogenetic furrow

, proneural cluster &&of imaginal disc

" "viable,visible,recessive,dominant,female fertile,male fertile,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,heat sensitive,lethal" "eye,microchaeta,macrochaeta,ectopic,sensillum trichodeum,sensillum campaniformium,sensillum basiconicum,anterior sternopleural bristle,anterior dorsocentral bristle,ocellar bristle,head bristle,heat sensitive,scutellar bristle,scutum & microchaeta-537.4,ommatidium,lens,interommatidial bristle,eye photoreceptor cell,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B" FBgn0053315 CR33315 - http://flybase.org/reports/FBgn0053315 pseudogene_attribute - - - CR33315 - CR33315 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262719 CG43163 - http://flybase.org/reports/FBgn0262719 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of mitotic cell cycle ; GO:0007346 | inferred from electronic annotation with InterPro:IPR028833 biological_process ; GO:0008150 | no biological data available midbody ; GO:0030496 | inferred from electronic annotation with InterPro:IPR028833 centrosome ; GO:0005813 | inferred from electronic annotation with InterPro:IPR028833 cellular_component ; GO:0005575 | no biological data available "CG43163, CG6902, CG6915" "IPR024983:CHAT domain, IPR028833:Tetratricopeptide repeat protein 28, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG43163 11-Aug-17 DroID_v2017_08 "Drer\sgut1, Drer\si:dkey-33c12.4, Drer\gpsm2, Drer\zgc:123010, Drer\ttc12, Drer\gpsm1b, Drer\ttc28, Drer\stip1" Scer\STI1 "Cele\ags-3, Cele\Y22D7AL.9" "Xtro\gpsm1, Xtro\gpsm2, Xtro\stip1, Xtro\ttc28, Xtro\sugt1" "Mmus\Stip1, Mmus\Sugt1, Mmus\Gpsm2, Mmus\Ttc12, Mmus\Ttc28, Mmus\Ttc25, Mmus\Gpsm1" "Hsap\STIP1, Hsap\GPSM2, Hsap\TTC12, Hsap\SUGT1, Hsap\TTC28, Hsap\GPSM1, Hsap\TTC31" FBgn0041783 S(Sev-CycE)D28 S(Sev-CycE)D28 http://flybase.org/reports/FBgn0041783 gene - - - S(Sev-CycE)D28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259118 mess messy mitochondria http://flybase.org/reports/FBgn0259118 gene - - - mess - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062609 Mod(var)1322 Mod(var)1322 http://flybase.org/reports/FBgn0062609 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1322, Mod(var)1322" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0000514 dvr divers http://flybase.org/reports/FBgn0000514 - gene - - - dvr - - 11-Aug-17 DroID_v2017_08 - - - - - - "semi-sterile,partially lethal - majority die,visible,wild-type" "wing,posterior scutellar bristle" FBgn0084038 CG41478 - http://flybase.org/reports/FBgn0084038 protein_coding_gene - - - CG41478 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014979 l(2)30l lethal (2) 30l http://flybase.org/reports/FBgn0014979 - gene - - - l(2)30l - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267955 CR46235 - http://flybase.org/reports/FBgn0267955 non_protein_coding_gene - - - "CR46235, lincRNA.335" - CR46235 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000252 cal coal http://flybase.org/reports/FBgn0000252 - gene - - - cal - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,body color defective" FBgn0266883 CR45344 - http://flybase.org/reports/FBgn0266883 non_protein_coding_gene - - - CR45344 - CR45344 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010897 l(3)06664 lethal (3) 06664 http://flybase.org/reports/FBgn0010897 - gene - - - l(3)06664 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0043464 18w::Tl 18w::Tl http://flybase.org/reports/FBgn0043464 engineered_fusion_gene - - - 18w::Tl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002104 l(2)57De lethal (2) 57De http://flybase.org/reports/FBgn0002104 - gene - - - l(2)57De - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030599 CG9030 - http://flybase.org/reports/FBgn0030599 protein_coding_gene - - - CG9030 - CG9030 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015436 l(1)5ACb lethal (1) 5ACb http://flybase.org/reports/FBgn0015436 - gene - - - l(1)5ACb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive,visible" "wing,thorax" FBgn0011009 l(3)s1754 lethal (3) s1754 http://flybase.org/reports/FBgn0011009 - gene - - - l(3)s1754 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262621 CG43145 - http://flybase.org/reports/FBgn0262621 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG43145, lincRNA.26" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG43145 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024152 alphaTub84B::bcd alphaTub84B::bcd http://flybase.org/reports/FBgn0024152 - engineered_fusion_gene - - - alphaTub84B::bcd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265792 CR44581 - http://flybase.org/reports/FBgn0265792 non_protein_coding_gene - - - "lincRNA.100, CR44581" - CR44581 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086895 pea peanuts http://flybase.org/reports/FBgn0086895 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR003029 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000000815" "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000815" spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000000815 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "CG8241, Prp22, cg8241, pea, prp22" "IPR001650:Helicase, C-terminal, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR003029:S1 domain, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR012340:Nucleic acid-binding, OB-fold, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022967:RNA-binding domain, S1" CG8241 11-Aug-17 DroID_v2017_08 "Drer\dhx32b, Drer\dhx33, Drer\dhx16, Drer\zgc:158828, Drer\dhx15, Drer\zcchc17, Drer\dhx40, Drer\dhx8, Drer\dhx38, Drer\dhx32a, Drer\dhx34" "Scer\PRP22, Scer\PRP43, Scer\PRP2, Scer\DHR2, Scer\PRP16" "Cele\mog-1, Cele\ddx-15, Cele\let-355, Cele\mog-5, Cele\mog-4" "Xtro\dhx15, Xtro\dhx35, Xtro\dhx33, Xtro\dhx40, Xtro\ythdc2, Xtro\dhx16, Xtro\dhx8, Xtro\dhx38, Xtro\dhx34" "Mmus\Ythdc2, Mmus\Dhx34, Mmus\Dqx1, Mmus\Dhx15, Mmus\Zcchc17, Mmus\Dhx35, Mmus\Dhx8, Mmus\Dhx16, Mmus\Dhx32, Mmus\Dhx38, Mmus\Dhx40, Mmus\Dhx33" "Hsap\ZCCHC17, Hsap\DHX15, Hsap\YTHDC2, Hsap\DHX8, Hsap\DHX33, Hsap\DQX1, Hsap\DHX38, Hsap\DHX40, Hsap\DHX34, Hsap\DHX35, Hsap\DHX32, Hsap\DHX16" DRSC07120 I -0.655126172 1.90293476 1.20572713 1.06831118 0.297519009 0.77536091 FBgn0037862 CG4706 - http://flybase.org/reports/FBgn0037862 protein_coding_gene "aconitate hydratase activity ; GO:0003994 | inferred from electronic annotation with InterPro:IPR006248 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR006248" tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:Q99798 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q99798 extracellular space ; GO:0005615 | inferred from direct assay CG4706 "IPR000573:Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, IPR001030:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain, IPR006248:Aconitase, mitochondrial-like, IPR018136:Aconitase family, 4Fe-4S cluster binding site, IPR015928:Aconitase/3-isopropylmalate dehydratase, swivel, IPR015931:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3, IPR015932:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2" CG4706 11-Aug-17 DroID_v2017_08 Drer\aco2 "Scer\MRPL49, Scer\LEU1, Scer\ACO1, Scer\ACO2, Scer\LYS4" "Cele\aco-1, Cele\aco-2" Xtro\aco2 "Mmus\Aco2, Mmus\Aco1, Mmus\Ireb2" "Hsap\IREB2, Hsap\ACO2, Hsap\ACO1" viable FBgn0050195 CG30195 - http://flybase.org/reports/FBgn0050195 protein_coding_gene - - - "CG13513, CG30195" IPR006629:LPS-induced tumour necrosis factor alpha factor CG30195 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040838 CG12599 - http://flybase.org/reports/FBgn0040838 protein_coding_gene - - - CG12599 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053296 CG33296 - http://flybase.org/reports/FBgn0053296 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transport ; GO:0006836 | inferred from sequence model transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 CG33296 IPR000175:Sodium:neurotransmitter symporter CG33296 11-Aug-17 DroID_v2017_08 Drer\zgc:158225 - Cele\snf-6 - Mmus\Slc6a7 Hsap\SLC6A7 FBgn0000727 frh fruh http://flybase.org/reports/FBgn0000727 - gene - - - "frh[RO], frh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" "stage 5 embryo,embryonic/first instar larval cuticle" FBgn0265083 CG44194 - http://flybase.org/reports/FBgn0265083 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrial respiratory chain complex assembly ; GO:0033108 | inferred from sequence or structural similarity with SGD:S000004208 mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from biological aspect of ancestor with PANTHER:PTN001007247 mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN001007247 mitochondrial intermembrane space ; GO:0005758 | inferred from sequence or structural similarity with SGD:S000004208 CG44194 IPR009069:Cysteine alpha-hairpin motif superfamily CG44194 11-Aug-17 DroID_v2017_08 Drer\si:ch211-215a9.5 Scer\COA4 - - Mmus\Coa4 Hsap\COA4 FBgn0015863 anon-240K anon-240K http://flybase.org/reports/FBgn0015863 - gene - - - anon-240K - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259277 C480 - http://flybase.org/reports/FBgn0259277 gene - - - C480 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing margin" FBgn0263778 CR43695 - http://flybase.org/reports/FBgn0263778 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43695, CR43695, CG15344, mdcds_61307" - CR43695 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033139 Tsp42Er Tetraspanin 42Er http://flybase.org/reports/FBgn0033139 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model "CG12837, Dm.Tsp42Er, Tsp42Er" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12837 11-Aug-17 DroID_v2017_08 Drer\cd63 - "Cele\tsp-3, Cele\tsp-7, Cele\tsp-1, Cele\tsp-9, Cele\tsp-2, Cele\tsp-14" - Mmus\Cd63 Hsap\CD63 viable FBgn0005528 l(2)52ACe lethal (2) 52ACe http://flybase.org/reports/FBgn0005528 - gene - - - l(2)52ACe - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050401 dany distal antenna-young http://flybase.org/reports/FBgn0050401 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" regulation of transcription from RNA polymerase II promoter involved in spermatogenesis ; GO:1902064 | inferred from mutant phenotype polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG30401, CG13496, dany" "IPR007889:DNA binding HTH domain, Psq-type, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG30401 11-Aug-17 DroID_v2017_08 - - - - Mmus\Tigd5 Hsap\TIGD5 viable FBgn0086076 snoRNA:MeU2-A31 - http://flybase.org/reports/FBgn0086076 snoRNA_gene - - - "snoRNA:MeU2-A31, MeU2-Am31, CR34705, mgU2-31, MeU2-A31" - CR34705 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003465 som sombre http://flybase.org/reports/FBgn0003465 - gene - - - som - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive,eye color defective,body color defective" "pigment cell,wing" FBgn0035134 CG1231 - http://flybase.org/reports/FBgn0035134 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000690, InterPro:IPR003604 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN001128910" - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR000690 CG1231 "IPR000690:Matrin/U1-C, C2H2-type zinc finger, IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013087:Zinc finger C2H2-type, IPR022755:Zinc finger, double-stranded RNA binding" CG1231 11-Aug-17 DroID_v2017_08 "Drer\zgc:171482, Drer\znf385b, Drer\zmat4a, Drer\znf346, Drer\znf385a, Drer\zmat4b, Drer\zmat3, Drer\zgc:114104, Drer\znf385c" - - "Xtro\zmat3, Xtro\krcc1, Xtro\znf385b, Xtro\znf385a, Xtro\znf346, Xtro\znf385c, Xtro\zmat4" "Mmus\Zfp385a, Mmus\Zmat1, Mmus\Zfp346, Mmus\Zmat4, Mmus\Zmat3, Mmus\Krcc1, Mmus\Zfp385b, Mmus\Zfp385c" "Hsap\KRCC1, Hsap\ZMAT4, Hsap\ZMAT1, Hsap\ZMAT3, Hsap\ZNF385B, Hsap\ZNF385A, Hsap\ZNF385C, Hsap\ZNF385D, Hsap\ZNF346" viable DRSC08267 I 1.629500545 2.611051055 0.849073902 -0.695067752 0.251734551 0.228278987 FBgn0002646 mapA midgut amylase pattern AMG http://flybase.org/reports/FBgn0002646 - gene - - - "map-AMG, mapA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085279 CG34250 - http://flybase.org/reports/FBgn0085279 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34250 - CG34250 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051019 CG31019 - http://flybase.org/reports/FBgn0051019 protein_coding_gene metallocarboxypeptidase activity ; GO:0004181 | inferred from electronic annotation with InterPro:IPR000834 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834 - CG31019 "IPR000834:Peptidase M14, carboxypeptidase A" CG31019 11-Aug-17 DroID_v2017_08 "Drer\agbl5, Drer\agbl2, Drer\agbl4, Drer\agtpbp1" - Cele\ccpp-6 "Xtro\agtpbp1, Xtro\agbl2, Xtro\agbl5, Xtro\agbl1, Xtro\agbl4" "Mmus\Agbl2, Mmus\Agbl5, Mmus\Agbl3, Mmus\Agbl1, Mmus\Agtpbp1, Mmus\Agbl4" "Hsap\AGTPBP1, Hsap\AGBL1, Hsap\AGBL3, Hsap\AGBL4, Hsap\AGBL2, Hsap\AGBL5" FBgn0035476 CG12766 - http://flybase.org/reports/FBgn0035476 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" - CG12766 "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG12766 11-Aug-17 DroID_v2017_08 "Drer\zgc:110366, Drer\zgc:56622, Drer\zgc:101765, Drer\akr1a1b, Drer\zgc:110782, Drer\akr1a1a, Drer\akr1b1, Drer\si:dkey-180p18.9" "Scer\GCY1, Scer\YDL124W, Scer\YJR096W, Scer\ARA1, Scer\YPR1, Scer\GRE3" "Cele\K07C5.2, Cele\F53F1.3, Cele\Y39G8B.1, Cele\T08H10.1, Cele\C35D10.6, Cele\ZK1290.5, Cele\Y39G8B.2, Cele\F53F1.2, Cele\C01G5.5, Cele\C56G3.2, Cele\C07D8.6, Cele\ZC443.1" "Xtro\akr1c8p, Xtro\akr1a1, Xtro\akr1d1, Xtro\akr1c2, Xtro\akr1b1, Xtro\akr1c1, Xtro\LOC548351" "Mmus\Akr1b7, Mmus\Akr1b10, Mmus\Akr1c14, Mmus\Akr1e1, Mmus\Akr1d1, Mmus\Akr1c20, Mmus\Akr1b3, Mmus\Akr1c12, Mmus\Akr1b8, Mmus\Akr1c6, Mmus\Akr1a1, Mmus\Akr1c21, Mmus\Akr1c19, Mmus\Akr1c13, Mmus\Akr1c18, Mmus\Akr1cl" "Hsap\AKR1B10, Hsap\AKR1C2, Hsap\AKR1D1, Hsap\AKR1A1, Hsap\AKR1C3, Hsap\AKR1C1, Hsap\AKR1B1, Hsap\AKR1B15, Hsap\AKR1C4, Hsap\AKR1E2" DRSC08295 K -0.284076084 0.338433952 0.71554448 0.449239076 -1.601557257 -0.169450502 FBgn0083257 E(smoDN)986 Enhancer of smoDN 986 http://flybase.org/reports/FBgn0083257 gene - - - E(smoDN)986 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084455 l(3)S000710 l(3)S000710 http://flybase.org/reports/FBgn0084455 gene - - - l(3)S000710 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035694 CG13299 - http://flybase.org/reports/FBgn0035694 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern chorion ; GO:0042600 | inferred by curator from GO:0007304 CG13299 - CG13299 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002548 Lg Large http://flybase.org/reports/FBgn0002548 - gene - - - Lg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "microchaeta,wing vein L4,wing vein L5,wing,postvertical bristle" FBgn0034797 nahoda nahoda http://flybase.org/reports/FBgn0034797 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT36793, CG12781, nahoda" "IPR000082:SEA domain, IPR000742:EGF-like domain, IPR005018:DOMON domain, IPR013032:EGF-like, conserved site, IPR013111:EGF-like domain, extracellular" CG12781 11-Aug-17 DroID_v2017_08 "Drer\zgc:163022, Drer\frrs1b, Drer\frrs1a" - "Cele\C09F9.2, Cele\B0393.4, Cele\C34C6.3, Cele\T26C11.2" Xtro\frrs1 "Mmus\Frrs1l, Mmus\Ggn, Mmus\Gprasp1, Mmus\Frrs1" "Hsap\FRRS1, Hsap\GPRASP2, Hsap\GGN, Hsap\TPRX1" viable FBgn0034470 Obp56d Odorant-binding protein 56d http://flybase.org/reports/FBgn0034470 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 olfactory behavior ; GO:0042048 | inferred from sequence or structural similarity with UniProtKB:O02372 response to pheromone ; GO:0019236 | inferred from sequence or structural similarity with UniProtKB:O02372 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:O02372 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "CT31326, CG11218, 56d, OBP56d, BEST:GH09027, BcDNA:RE22207, Obp56d, obp56d, DmelObp56d, RH69634p" IPR006170:Pheromone/general odorant binding protein CG11218 11-Aug-17 DroID_v2017_08 - - Cele\T28A11.16 - - - adult stage proboscis

viable FBgn0029964 CG1409 - http://flybase.org/reports/FBgn0029964 protein_coding_gene - protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000273250 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000273250 "D.M.BLPp, BcDNA:AT29287, CG1409" IPR005341:Mitochondrial import inner membrane translocase subunit Tim16 CG1409 11-Aug-17 DroID_v2017_08 Drer\pam16 Scer\PAM16 Cele\F45G2.8 Xtro\coro7 Mmus\Pam16 "Hsap\PAM16, Hsap\CORO7-PAM16" viable FBgn0014244 l(2)32Ae lethal (2) 32Ae http://flybase.org/reports/FBgn0014244 - gene - - - l(2)32Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019957 ND-42 NADH dehydrogenase (ubiquinone) 42 kDa subunit http://flybase.org/reports/FBgn0019957 - protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95299 NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from sequence or structural similarity with MGI:MGI:1914523 "regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95299" mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95299 "CG6343, ND42, NdufA10, NUDM, ND-42, A10" "IPR015828:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031314:Deoxynucleoside kinase domain" CG6343 11-Aug-17 DroID_v2017_08 Drer\ndufa10 - Cele\nuo-4 Xtro\ndufa10 Mmus\Ndufa10 Hsap\NDUFA10 "neuroanatomy defective,progressive,viable,visible,body color defective" "rhabdomere,progressive,eye photoreceptor cell,retinal pigment cell,trichogen cell,mesothoracic tergum" FBgn0001184 hdp-b heldup b http://flybase.org/reports/FBgn0001184 - gene - - - "hdp, hdp-b" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0060496 l(3)S107707 lethal (3) S107707 http://flybase.org/reports/FBgn0060496 gene - - - "1077/07, l(3)S107707" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0002379 l(3)93Ba lethal (3) 93Ba http://flybase.org/reports/FBgn0002379 - gene - - - "er7, l(3)er7, l(3)93Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002046 l(2)37Dj lethal (2) 37Dj http://flybase.org/reports/FBgn0002046 - gene - - - "l(2)OE31, l(2)37Dj" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058122 CG40122 - http://flybase.org/reports/FBgn0058122 protein_coding_gene - - - CG40122 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030351 CG1840 - http://flybase.org/reports/FBgn0030351 protein_coding_gene - immune system process ; GO:0002376 | inferred from biological aspect of ancestor with PANTHER:PTN001047971 endoplasmic reticulum calcium ion homeostasis ; GO:0032469 | inferred from biological aspect of ancestor with PANTHER:PTN000423974 calcium ion transport ; GO:0006816 | inferred from biological aspect of ancestor with PANTHER:PTN000423974 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000423974 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000423974 "AAF48112, BcDNA:LD12750, CG1840" IPR024491:Selenoprotein SelK/SelG CG1840 11-Aug-17 DroID_v2017_08 Drer\selk - Cele\Y41E3.8 Xtro\selk Mmus\Selenok Hsap\SELENOK FBgn0058172 CR40172 - http://flybase.org/reports/FBgn0058172 non_protein_coding_gene - - - "CG40172, CR40172" - CR40172 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060464 l(3)S114602 lethal (3) S114602 http://flybase.org/reports/FBgn0060464 gene - - - "1146/02, l(3)S114602" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035193 CG9192 - http://flybase.org/reports/FBgn0035193 protein_coding_gene - - - CG9192 - CG9192 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259394 EP-380 - http://flybase.org/reports/FBgn0259394 gene - - - EP-380 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,planar polarity defective" wing FBgn0013583 l(3)ry85 lethal (3) ry85 http://flybase.org/reports/FBgn0013583 - gene - - - "l(3)85, l(3)ry85" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000766 fs(1)A1010 female sterile (1) A1010 http://flybase.org/reports/FBgn0000766 - gene - - - "fs(1)1010ts, fs(1)A1010" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,mitotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect,blastoderm embryo" FBgn0025492 l(3)82Da lethal (3) 82Da http://flybase.org/reports/FBgn0025492 - gene - - - l(3)82Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0060591 l(3)S093108a lethal (3) S093108a http://flybase.org/reports/FBgn0060591 gene - - - "0931/08, l(3)S093108a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0051077 CG31077 - http://flybase.org/reports/FBgn0051077 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG31077 IPR002557:Chitin binding domain CG31077 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\F48E3.8, Cele\R02F2.4, Cele\cpg-2, Cele\W03F11.1, Cele\cbd-1" - Mmus\Fbn1 Hsap\MATN2 "viable,fertile" FBgn0021753 3L-B 3L-B http://flybase.org/reports/FBgn0021753 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3L-B - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,viable" wing FBgn0062648 EP443 EP443 http://flybase.org/reports/FBgn0062648 gene - - - "EP(X)0443, EP443" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261788 Ank2 Ankyrin 2 http://flybase.org/reports/FBgn0261788 protein_coding_gene cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity spectrin binding ; GO:0030507 | inferred from biological aspect of ancestor with PANTHER:PTN001537955 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000488 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with Ank2 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype protein targeting to plasma membrane ; GO:0072661 | inferred from biological aspect of ancestor with PANTHER:PTN001537955 positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay presynaptic periactive zone ; GO:0036062 | inferred from direct assay presynaptic membrane ; GO:0042734 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001537955 "Ank2, CG32377/CG34416, ank2-L, CG34416, SP2523, CG42734, ank2, CG7462, Dank2, ESTS:149B10S, CG34158, sp2523, CG7493, CG32375, CG18227, CG18768, CG34121, dank2, CG18025, CG32377, CG32373, DAnk2" "IPR011029:Death-like domain, IPR002110:Ankyrin repeat, IPR000906:ZU5 domain, IPR000488:Death domain, IPR020683:Ankyrin repeat-containing domain" CG42734 11-Aug-17 DroID_v2017_08 "Drer\trpa1b, Drer\ankdd1b, Drer\ankrd44, Drer\si:dkey-86e18.2, Drer\ank1b, Drer\si:ch73-193i2.2, Drer\pidd1, Drer\ank1a, Drer\ankk1, Drer\ankrd28b, Drer\hace1, Drer\trpn1, Drer\ankdd1a, Drer\ankef1a, Drer\ankef1b, Drer\tnksa, Drer\ankrd1b, Drer\ank2a, Drer\tnksb, Drer\ankrd52b, Drer\ankrd52a, Drer\ank2b, Drer\ank3b, Drer\ank3a, Drer\si:ch211-203b8.6" Scer\YAR1 "Cele\trp-4, Cele\unc-44, Cele\trpa-1" "Xtro\ank1, Xtro\ankdd1a, Xtro\hace1, Xtro\cat2, Xtro\tnks2, Xtro\ank3, Xtro\ank2, Xtro\ankk1, Xtro\asb7, Xtro\ankef1, Xtro\LOC100492885" "Mmus\Ankrd42, Mmus\Trpa1, Mmus\Ank2, Mmus\Hace1, Mmus\Ankdd1a, Mmus\Ankrd65, Mmus\Ankdd1b, Mmus\Tnks, Mmus\Tnks2, Mmus\Ankrd52, Mmus\Sowahd, Mmus\Ankrd28, Mmus\Ankrd60, Mmus\Ankk1, Mmus\Ank1, Mmus\Ankrd44, Mmus\Ankef1, Mmus\Ank3, Mmus\Ankrd61, Mmus\Rnasel, Mmus\Ankrd53, Mmus\Asb7, Mmus\Sowahc, Mmus\Pidd1" "Hsap\ANKRD65, Hsap\TNKS, Hsap\ANK3, Hsap\ANKRD60, Hsap\ANK2, Hsap\ANKRD44, Hsap\ANK1, Hsap\PIDD1, Hsap\ANKEF1, Hsap\ANKRD53, Hsap\ASB7, Hsap\ANKRD61, Hsap\ANKK1, Hsap\SOWAHD, Hsap\TNKS2, Hsap\HACE1, Hsap\ANKRD52, Hsap\ANKRD28, Hsap\ANKDD1B, Hsap\ANKDD1A, Hsap\SOWAHC, Hsap\RNASEL" FBgn0003419 slb slim body http://flybase.org/reports/FBgn0003419 - gene - - - slb - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" FBgn0012034 AcCoAS Acetyl Coenzyme A synthase http://flybase.org/reports/FBgn0012034 FBgn0043802 protein_coding_gene acetate-CoA ligase activity ; GO:0003987 | inferred from electronic annotation with InterPro:IPR011904 AMP binding ; GO:0016208 | inferred from electronic annotation with InterPro:IPR011904 acetyl-CoA biosynthetic process from acetate ; GO:0019427 | inferred from electronic annotation with InterPro:IPR011904 behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype - "CG9390, ACS, BEST:GH28401, AcCoAS, AcCoAs, dACS" "IPR000873:AMP-dependent synthetase/ligase, IPR011904:Acetate-CoA ligase, IPR025110:AMP-binding enzyme C-terminal domain, IPR020845:AMP-binding, conserved site, IPR032387:Acetyl-coenzyme A synthetase, N-terminal domain" CG9390 11-Aug-17 DroID_v2017_08 "Drer\acss2, Drer\acsm3, Drer\acss2l, Drer\aacs, Drer\acss1, Drer\acss3" "Scer\ACS2, Scer\ACS1" "Cele\acs-6, Cele\acs-19" "Xtro\aacs, Xtro\acss1, Xtro\acss2.2, Xtro\acss3, Xtro\acss2.1, Xtro\acsm3" "Mmus\Acss3, Mmus\Acsm4, Mmus\Acsm1, Mmus\Aacs, Mmus\Acss2, Mmus\Acsm2, Mmus\Acsm3, Mmus\Acsm5, Mmus\Acss1" "Hsap\ACSM1, Hsap\ACSS1, Hsap\ACSM3, Hsap\ACSM5, Hsap\ACSM6, Hsap\ACSM2B, Hsap\ACSM4, Hsap\ACSS3, Hsap\AACS, Hsap\ACSS2, Hsap\ACSM2A" "viable,fertile,hypoactive,conditional,chemical sensitive,smell perception defective" FBgn0084274 2.1.72 2.1.72 http://flybase.org/reports/FBgn0084274 gene - - - 2.1.72 - - 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,eye color defective" pigment cell FBgn0040645 CG14581 - http://flybase.org/reports/FBgn0040645 protein_coding_gene - - - CG14581 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,visible" mesothoracic tergum FBgn0000815 fs(1)K524 female sterile (1) K524 http://flybase.org/reports/FBgn0000815 - gene - - - fs(1)K524 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,visible,heat sensitive" "eye,macrochaeta,ovary" FBgn0266178 pre-mod(mdg4)-B - http://flybase.org/reports/FBgn0266178 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-B, CG44884" "IPR007588:Zinc finger, FLYWCH-type" CG44884 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265650 CR44457 - http://flybase.org/reports/FBgn0265650 non_protein_coding_gene - - - "lincRNA.312, CR44457" - CR44457 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036918 Pfdn6 Prefoldin 6 http://flybase.org/reports/FBgn0036918 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR002777 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000484524 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000484524 neurogenesis ; GO:0022008 | inferred from mutant phenotype chaperone-mediated protein complex assembly ; GO:0051131 | inferred from biological aspect of ancestor with PANTHER:PTN000484524 prefoldin complex ; GO:0016272 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000484524 "BcDNA:GH28557, CG7770, Pfdn6, pfdn6" IPR002777:Prefoldin beta-like CG7770 11-Aug-17 DroID_v2017_08 Drer\pfdn6 "Scer\GIM4, Scer\YKE2" "Cele\pfd-2, Cele\pfd-6" Xtro\pfdn6 "Mmus\Pfdn6, Mmus\Pfdn2" Hsap\PFDN6 "lethal,neuroanatomy defective" ganglion mother cell FBgn0050490 CG30490 - http://flybase.org/reports/FBgn0050490 protein_coding_gene - - - CG30490 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039854 CG1635 - http://flybase.org/reports/FBgn0039854 protein_coding_gene acyl-CoA hydrolase activity ; GO:0047617 | inferred from sequence or structural similarity with MGI:MGI:1928939 acyl-CoA metabolic process ; GO:0006637 | inferred from sequence or structural similarity with MGI:MGI:1928939 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:1928939 CG1635 "IPR029069:HotDog domain, IPR033120:Hotdog acyl-CoA thioesterase (ACOT)-type domain" CG1635 11-Aug-17 DroID_v2017_08 "Drer\acot11a, Drer\acot11b, Drer\acot9.2, Drer\acot12, Drer\acot7, Drer\acot9.1" - "Cele\T07D3.9, Cele\T22B7.7, Cele\F57F4.1" "Xtro\acot12, Xtro\acot7, Xtro\acot11, Xtro\acot9" "Mmus\Acot7, Mmus\Acot9, Mmus\Acot10, Mmus\Acot11, Mmus\Acot12" "Hsap\ACOT9, Hsap\ACOT11, Hsap\ACOT12, Hsap\ACOT7" viable DRSC25487 K 0.404437391 0.340482547 0.736627187 -0.111049377 1.875449349 0.102175915 FBgn0004090 l(2)60Ca lethal (2) 60Ca http://flybase.org/reports/FBgn0004090 - gene - - - l(2)60Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0003127 port port http://flybase.org/reports/FBgn0003127 - gene - - - port - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective" pigment cell FBgn0037782 Npc2d Niemann-Pick type C-2d http://flybase.org/reports/FBgn0037782 protein_coding_gene sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 intracellular cholesterol transport ; GO:0032367 | inferred from electronic annotation with InterPro:IPR033916 sterol transport ; GO:0015918 | inferred from sequence or structural similarity with Npc2a - "npc2d, Npc2d, CG12813" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set, IPR033916:ML domain, Npc2 like" CG12813 11-Aug-17 DroID_v2017_08 "Drer\npc2, Drer\zgc:193725" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 viable FBgn0034948 PPP1R15 Protein phosphatase 1 regulatory subunit 15 http://flybase.org/reports/FBgn0034948 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B - endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG3825, GADD34, Dm-GADD34, Gadd34, dGADD34, gadd34, dPPP1R15, PPP1R15" "IPR019523:Protein phosphatase 1, regulatory subunit 15A/B, C-terminal" CG3825 11-Aug-17 DroID_v2017_08 "Drer\ppp1r15a, Drer\ppp1r15b" - - - "Mmus\Ppp1r15b, Mmus\Ppp1r15a" "Hsap\PPP1R15A, Hsap\PPP1R15B" "visible,partially lethal - majority die,some die during pupal stage,some die during embryonic stage,developmental rate defective,viable,fertile" mesothoracic tergum DRSC04422 IE -0.678635744 -2.816865093 -1.955411417 -2.743336041 0.03544586 0.130304194 FBgn0005042 E(var)28AB Enhancer of variegation 28AB http://flybase.org/reports/FBgn0005042 - gene - - - E(var)28AB - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033652 ths thisbe http://flybase.org/reports/FBgn0033652 protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR002209 fibroblast growth factor receptor binding ; GO:0005104 | traceable author statement glial cell development ; GO:0021782 | inferred from mutant phenotype inferred from genetic interaction with pyr mesoderm development ; GO:0007498 | inferred from mutant phenotype larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype glial cell differentiation ; GO:0010001 | inferred from mutant phenotype myoblast migration ; GO:0051451 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from genetic interaction with pyr - "Neu4, fgf8-like, FGF8-like1, CG12443, DFGF8-1, ths, DmThs, Ths" "IPR008996:Cytokine IL1/FGF, IPR002209:Fibroblast growth factor family" CG12443 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | stage 5 ventral neurogenic region

"partially lethal - majority die,recessive,cell migration defective,some die during embryonic stage,viable,fertile" "glial cell,mesoderm,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,segment border muscle,embryonic/larval midgut longitudinal visceral muscle,longitudinal visceral muscle primordium,ventral oblique muscle,longitudinal visceral muscle primordium | embryonic stage 12,longitudinal visceral muscle primordium | embryonic stage 13,embryonic/larval midgut longitudinal visceral muscle | embryonic stage 17,embryonic pericardial cell,supernumerary,eye photoreceptor cell" FBgn0265795 CR44584 - http://flybase.org/reports/FBgn0265795 non_protein_coding_gene - - - CR44584 - CR44584 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262767 Su(E1)-A gene ; SO:0000704 http://flybase.org/reports/FBgn0262767 gene - - - Su(E1)-A - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065863 l(2)SH0271 lethal (2) SH0271 http://flybase.org/reports/FBgn0065863 gene - - - "l(2)SH0271, l(2)SH2 0271" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265596 CR44423 - http://flybase.org/reports/FBgn0265596 non_protein_coding_gene - - - CR44423 - CR44423 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038705 CG11626 - http://flybase.org/reports/FBgn0038705 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR008758 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008758 - CG11626 "IPR008758:Peptidase S28, IPR029058:Alpha/Beta hydrolase fold" CG11626 11-Aug-17 DroID_v2017_08 Drer\prss16 - "Cele\pcp-4, Cele\pcp-2, Cele\pcp-3, Cele\F56F10.1, Cele\pcp-1, Cele\K12H4.7, Cele\C26B9.5, Cele\pcp-5, Cele\F19C7.2, Cele\F28E10.5, Cele\F19C7.4" "Xtro\LOC100145763, Xtro\prss16" "Mmus\Prss16, Mmus\Dpp7" "Hsap\DPP7, Hsap\PRSS16" viable FBgn0262365 CG43063 - http://flybase.org/reports/FBgn0262365 protein_coding_gene - - - "CG43063, MIP20204" - CG43063 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011427 l(3)j10B6 lethal (3) j10B6 http://flybase.org/reports/FBgn0011427 - gene - - - l(3)j10B6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011977 tRNA:Ser-CGA-1-3 transfer RNA:Serine-CGA 1-3 http://flybase.org/reports/FBgn0011977 "FBgn0003826, FBgn0011968, FBgn0011973, FBgn0052608, FBgn0060061" tRNA_gene UCG codon-amino acid adaptor activity ; GO:0033408 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033408 cytosol ; GO:0005829 | inferred by curator from GO:0033408 "444-T50, Ser-tRNA-4, tRNA-Ser, 444[[T50]], tRNA[Ser], Ser tRNA[Ser], AE002593.trna13-SerCGA, tRNA:S:CGA:AE002593-c, CR32608, tRNA:ser, tRNA:S, tRNA:ser4, tRNA:S4, tRNA:ser4:12Ee, tRNA[[Ser]], chrX.trna22-SerCGA, tRNA-Ser-CGA-1-3, tRNA:Ser-CGA-1-3, tRNA:S4:12Ee, UCG" - CR32608 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038102 CG14383 - http://flybase.org/reports/FBgn0038102 protein_coding_gene - - - CG14383 - CG14383 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024340 KHD-11 KH domain cDNA KHD-11 http://flybase.org/reports/FBgn0024340 - gene - - - KHD-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027264 l(1)G0221 lethal (1) G0221 http://flybase.org/reports/FBgn0027264 - gene - - - l(1)G0221 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0065525 l(2)SH1120 lethal (2) SH1120 http://flybase.org/reports/FBgn0065525 gene - - - "l(2)SH1120, l(2)SH2 1120" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051331 tRNA:Phe-GAA-1-7 transfer RNA:Phenylalanine-GAA 1-7 http://flybase.org/reports/FBgn0051331 tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "AE002708.trna54-PheGAA, tRNA:F:GAA:AE002708-c, CR31331, chr3R.trna60-PheGAA, tRNA-Phe-GAA-1-7, tRNA:Phe-GAA-1-7, tRNA:CR31331, UUC" - CR31331 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034151 CG15617 - http://flybase.org/reports/FBgn0034151 protein_coding_gene - - - "CT35755, CG15617" IPR001478:PDZ domain CG15617 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036250 Ir68b Ionotropic receptor 68b http://flybase.org/reports/FBgn0036250 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "CT38092, CG17152, DmelIR68b, Ir68b, IR68b" IPR001320:Ionotropic glutamate receptor CG17152 11-Aug-17 DroID_v2017_08 "Drer\grin1b, Drer\grid1a, Drer\LOC100537813, Drer\grin1a, Drer\grid1b" - "Cele\nmr-1, Cele\glr-8" - "Mmus\Grin1, Mmus\Grik4, Mmus\Grid1" "Hsap\GRID1, Hsap\GRID2, Hsap\GRIN1" FBgn0017434 anon-28Ce anon-28Ce http://flybase.org/reports/FBgn0017434 - gene - - - anon-28Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000518 dw-b dwarf b http://flybase.org/reports/FBgn0000518 - gene - - - dw-b - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "adult abdomen,adult thorax" FBgn0037685 Or85f Odorant receptor 85f http://flybase.org/reports/FBgn0037685 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "85f, DOR32, 85D.1, CG16755, Or85f, DmOr85f" "IPR004117:Olfactory receptor, insect" CG16755 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020323 anon-82Fa anon-82Fa http://flybase.org/reports/FBgn0020323 - gene - - - "506, anon-82Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267966 CR46246 - http://flybase.org/reports/FBgn0267966 non_protein_coding_gene - - - CR46246 - CR46246 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011139 l(1)Q215 lethal (1) Q215 http://flybase.org/reports/FBgn0011139 FBgn0010210 gene - - - l(1)Q215 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266824 CR45286 - http://flybase.org/reports/FBgn0266824 non_protein_coding_gene - - - CR45286 - CR45286 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267339 p38c p38c MAP kinase http://flybase.org/reports/FBgn0267339 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR003527, InterPro:IPR017441 MAP kinase activity ; GO:0004707 | inferred from direct assay" regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from genetic interaction with Ask1 regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from mutant phenotype regulation of response to oxidative stress ; GO:1902882 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 cytoplasm ; GO:0005737 | inferred from direct assay "p38c, CG33338, P38c, Dp38c, dMPK2B, Mpk2B, dp38c, p38, P38" "IPR000719:Protein kinase domain, IPR003527:Mitogen-activated protein (MAP) kinase, conserved site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG33338 11-Aug-17 DroID_v2017_08 "Drer\mapk12b, Drer\mapk11, Drer\mapk12a, Drer\mapk15, Drer\zgc:171775, Drer\mapk8a, Drer\mapk14b, Drer\mapk14a, Drer\mapk8b, Drer\mapk13, Drer\mapk4, Drer\mapk9, Drer\mapk1, Drer\mapk7, Drer\mapk6, Drer\mapk3" "Scer\HOG1, Scer\SMK1, Scer\SLT2, Scer\FUS3, Scer\KSS1, Scer\KDX1" "Cele\kgb-1, Cele\pmk-3, Cele\pmk-1, Cele\mpk-1, Cele\mpk-2, Cele\pmk-2, Cele\F09C12.2, Cele\C05D10.2, Cele\jnk-1, Cele\C49C3.10, Cele\Y51B9A.9, Cele\kgb-2, Cele\K11H12.9" "Xtro\mapk7, Xtro\mapk12, Xtro\LOC100145045, Xtro\mapk4, Xtro\mapk1, Xtro\mapk14, Xtro\mapk8, Xtro\mapk10, Xtro\mapk6, Xtro\mapk15, Xtro\mapk11" "Mmus\Mapk11, Mmus\Mapk4, Mmus\Uhmk1, Mmus\Mapk6, Mmus\Mapk9, Mmus\Mapk8, Mmus\Mapk1, Mmus\Mapk15, Mmus\Mapk12, Mmus\Mapk10, Mmus\Mapk7, Mmus\Mapk3, Mmus\Mapk14, Mmus\Mapk13" "Hsap\MAPK7, Hsap\MAPK6, Hsap\MAPK12, Hsap\MAPK13, Hsap\MAPK1, Hsap\MAPK8, Hsap\MAPK10, Hsap\MAPK3, Hsap\MAPK9, Hsap\UHMK1, Hsap\MAPK11, Hsap\MAPK4, Hsap\MAPK15, Hsap\MAPK14" FBgn0021738 Crg-1 Circadianly Regulated Gene http://flybase.org/reports/FBgn0021738 FBgn0052788 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "crg1, CG32788, Crg-1, Crg1" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG32788 11-Aug-17 DroID_v2017_08 "Drer\zgc:171734, Drer\foxn1" "Scer\HCM1, Scer\FHL1, Scer\FKH2, Scer\FKH1" - - "Mmus\Foxr2, Mmus\Foxr1, Mmus\Foxn1" "Hsap\FOXR2, Hsap\FOXN1, Hsap\FOXR1" viable FBgn0028133 l(3)S051007a lethal (3) S051007a http://flybase.org/reports/FBgn0028133 gene - - - "0510/07, l(3)S051007, l(3)S051007a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021860 l(2)k14308 lethal (2) k14308 http://flybase.org/reports/FBgn0021860 - gene - - - l(2)k14308 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001888 l(2)21Db lethal (2) 21Db http://flybase.org/reports/FBgn0001888 - gene - - - "l(2)neh-2, l(2)neh2, l(2)21Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0082305 Ndg::LpR2 Ndg::LpR2 http://flybase.org/reports/FBgn0082305 engineered_fusion_gene - - - Ndg::LpR2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015037 Cyp4p1 Cytochrome P450-4p1 http://flybase.org/reports/FBgn0015037 "FBgn0033396, FBgn0044596" protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4p1, P450, P-450, CG10842, anon-WO0140519.35, Cyp4p1, CYP4p1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10842 11-Aug-17 DroID_v2017_08 "Drer\cyp46a1.1, Drer\cyp3c3, Drer\cyp26b1, Drer\cyp3c4, Drer\cyp3c1, Drer\cyp26a1, Drer\cyp4t8, Drer\cyp4f3, Drer\cyp3c2, Drer\LOC100329425, Drer\cyp20a1, Drer\cyp46a1.4, Drer\cyp46a1.3, Drer\cyp46a1.2, Drer\cyp19a1a, Drer\cyp19a1b, Drer\cyp3a65, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp26c1" "Scer\DIT2, Scer\ERG5" "Cele\cyp-37A1, Cele\cyp-25A2, Cele\cyp-29A2, Cele\cyp-29A3, Cele\cyp-25A4, Cele\cyp-37B1, Cele\cyp-31A2, Cele\cyp-13A4, Cele\cyp-13A7, Cele\cyp-13A5, Cele\cyp-25A3, Cele\cyp-13A1, Cele\cyp-13A8, Cele\cyp-25A1, Cele\cyp-29A4, Cele\cyp-13A10, Cele\cyp-32A1, Cele\cyp-13A3, Cele\cyp-13A12, Cele\cyp-13A11, Cele\cyp-31A3, Cele\cyp-42A1, Cele\cyp-32B1" "Xtro\mgc108213, Xtro\cyp26b1, Xtro\cyp4b1.2, Xtro\cyp26c1, Xtro\cyp26a1, Xtro\cyp20a1, Xtro\LOC100488227, Xtro\cyp4v2, Xtro\cyp4b1, Xtro\cyp4f2, Xtro\cyp4f22, Xtro\LOC100487918, Xtro\cyp19a1" "Mmus\Cyp4a29, Mmus\Cyp4a31, Mmus\Cyp4a10, Mmus\Cyp4v3, Mmus\Cyp46a1, Mmus\Cyp26c1, Mmus\Cyp4f18, Mmus\Cyp3a11, Mmus\Cyp4f39, Mmus\Cyp3a41a, Mmus\Cyp4b1, Mmus\Cyp4a12b, Mmus\Cyp26a1, Mmus\Cyp4f40, Mmus\Cyp3a16, Mmus\Cyp3a59, Mmus\Cyp4a30b, Mmus\Cyp3a41b, Mmus\Cyp4x1, Mmus\Cyp3a25, Mmus\Cyp4a12a, Mmus\Cyp4a14, Mmus\Cyp3a13, Mmus\Cyp4f14, Mmus\Cyp3a57, Mmus\Cyp4f37, Mmus\Cyp3a44, Mmus\Cyp19a1, Mmus\Cyp26b1, Mmus\Cyp4a32, Mmus\Cyp20a1, Mmus\Cyp4f13, Mmus\Cyp4f16, Mmus\Cyp4f15, Mmus\Cyp4f17" "Hsap\CYP4F11, Hsap\CYP20A1, Hsap\CYP26B1, Hsap\CYP4F22, Hsap\CYP3A7, Hsap\CYP4V2, Hsap\CYP4X1, Hsap\CYP4Z1, Hsap\CYP26C1, Hsap\CYP4F12, Hsap\CYP46A1, Hsap\CYP4F3, Hsap\CYP4A11, Hsap\CYP19A1, Hsap\CYP3A43, Hsap\CYP4B1, Hsap\CYP3A5, Hsap\CYP3A4, Hsap\CYP4F2, Hsap\CYP4A22, Hsap\CYP26A1, Hsap\CYP4F8" viable FBgn0037814 CG6325 - http://flybase.org/reports/FBgn0037814 protein_coding_gene - - - CG6325 "IPR032734:DDB1- and CUL4-associated factor 15, WD40 repeat-containing domain" CG6325 11-Aug-17 DroID_v2017_08 Drer\dcaf15 - - Xtro\dcaf15 Mmus\Dcaf15 Hsap\DCAF15 "viable,fertile,visible" mesothoracic tergum FBgn0002806 ms(1)20Aa male sterile (1) 20Aa http://flybase.org/reports/FBgn0002806 - gene - - - "ms(1)B, ms(1)20A, ms(1)20Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0266273 T:GPI-lynx1 GPI targeting signal of lynx1 protoxin http://flybase.org/reports/FBgn0266273 engineered_foreign_region - - - T:GPI-lynx1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024886 l(2)00455b lethal (2) 00455b http://flybase.org/reports/FBgn0024886 - gene - - - "0455, l(2)00455, l(2)00455b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067643 sve sverdrup http://flybase.org/reports/FBgn0067643 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sve - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "dorsal appendage,germline clone,egg" FBgn0264503 CG43902 - http://flybase.org/reports/FBgn0264503 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43902, CG15311, CG12644" - CG43902 11-Aug-17 DroID_v2017_08 - - - - - - DRSC17999 IEK 1.196193199 -2.610716765 -0.605066916 -3.483496782 -0.909908606 -2.343080512 FBgn0264865 CR44056 - http://flybase.org/reports/FBgn0264865 non_protein_coding_gene - - - CR44056 - CR44056 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030999 Mur18B Mucin related 18B http://flybase.org/reports/FBgn0030999 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "anon-WO0140519.120, CG7874, Mur18B" IPR002557:Chitin binding domain CG7874 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040713 CG15392 - http://flybase.org/reports/FBgn0040713 protein_coding_gene - - - CG15392 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261994 CG42812 - http://flybase.org/reports/FBgn0261994 protein_coding_gene - - - "CG42812, CG18669" IPR006631:Protein of unknown function DM4/12 CG42812 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037141 DNApol-eta DNApol-eta http://flybase.org/reports/FBgn0037141 protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR017961 DNA-directed DNA polymerase activity ; GO:0003887 | inferred from direct assay inferred from mutant phenotype response to radiation ; GO:0009314 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype translesion synthesis ; GO:0019985 | inferred from sequence or structural similarity with HGNC:9181 inferred from direct assay translesion synthesis ; GO:0019985 | non-traceable author statement UV protection ; GO:0009650 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Dmpol eta, DNApol-eta, AAF51794, drad30A, POLH, CG7143, pol h, dPoleta, pol eta, DNApoleta, DNA pol eta, DNA pol-eta" "IPR001126:UmuC domain, IPR017061:DNA polymerase eta/kappa, IPR017961:DNA polymerase, Y-family, little finger domain" CG7143 11-Aug-17 DroID_v2017_08 "Drer\polh, Drer\poli, Drer\polk, Drer\esco1, Drer\esco2" "Scer\RAD30, Scer\REV1, Scer\ECO1" "Cele\polk-1, Cele\polh-1, Cele\F08F8.4" Xtro\polk "Mmus\Polh, Mmus\Esco1, Mmus\Poli, Mmus\Polk, Mmus\Esco2" "Hsap\ESCO1, Hsap\ESCO2, Hsap\POLK, Hsap\POLH, Hsap\POLI" "viable,fertile,radiation sensitive,maternal effect,chemical sensitive,DNA repair defective,visible,partially lethal - majority die,some die during pupal stage" "mitotic spindle | maternal effectBSC284),mitotic spindle | maternal effect,trichogen cell,mesothoracic tergum" FBgn0065918 l(2)SH0161 lethal (2) SH0161 http://flybase.org/reports/FBgn0065918 gene - - - "l(2)SH0161, l(2)SH2 0161" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264946 CR44115 - http://flybase.org/reports/FBgn0264946 non_protein_coding_gene - - - CR44115 - CR44115 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003173 pwc pink wing c http://flybase.org/reports/FBgn0003173 - gene - - - "pw-c, pwc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,recessive,visible,viable,poor" "pigment cell,wing" FBgn0069116 mus214 mutagen-sensitive 214 http://flybase.org/reports/FBgn0069116 gene - - - mus214 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0038354 CG5404 - http://flybase.org/reports/FBgn0038354 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 CG5404 "IPR011547:SLC26A/SulP transporter domain, IPR001902:SLC26A/SulP transporter, IPR002645:STAS domain" CG5404 11-Aug-17 DroID_v2017_08 "Drer\slc26a6l, Drer\slc26a10, Drer\slc26a4, Drer\slc26a2, Drer\slc26a1, Drer\slc26a3.1, Drer\slc26a6, Drer\slc26a5, Drer\si:ch211-117c9.2, Drer\slc26a3.2, Drer\slc26a11" "Scer\SUL2, Scer\YGR125W, Scer\YPR003C, Scer\SUL1" "Cele\sulp-7, Cele\sulp-3, Cele\sulp-5, Cele\sulp-4, Cele\sulp-8, Cele\sulp-6, Cele\sulp-1, Cele\sulp-2" "Xtro\slc26a6, Xtro\slc26a10, Xtro\slc26a1, Xtro\slc26a4, Xtro\slc26a2, Xtro\slc26a7, Xtro\slc26a5, Xtro\slc26a9, Xtro\slc26a11" "Mmus\Slc26a9, Mmus\Slc26a3, Mmus\Slc26a5, Mmus\Slc26a10, Mmus\Slc26a11, Mmus\Slc26a8, Mmus\Slc26a4, Mmus\Slc26a7, Mmus\Slc26a6, Mmus\Slc26a2, Mmus\Slc26a1" "Hsap\SLC26A11, Hsap\SLC26A6, Hsap\SLC26A8, Hsap\SLC26A7, Hsap\SLC26A10, Hsap\SLC26A2, Hsap\SLC26A3, Hsap\SLC26A1, Hsap\SLC26A5, Hsap\SLC26A4, Hsap\SLC26A9" viable DRSC15793 E 1.025096929 0.693032021 1.900732867 1.34301919 -0.561009081 -0.150266804 FBgn0038877 CG3308 - http://flybase.org/reports/FBgn0038877 protein_coding_gene deoxyribonuclease activity ; GO:0004536 | inferred from biological aspect of ancestor with PANTHER:PTN000006754 DNA catabolic process ; GO:0006308 | inferred from biological aspect of ancestor with PANTHER:PTN000006754 - CG3308 "IPR001130:TatD family, IPR032466:Metal-dependent hydrolase" CG3308 11-Aug-17 DroID_v2017_08 "Drer\tatdn3, Drer\tatdn1, Drer\tatdn2, Drer\LOC571912" "Scer\YBL055C, Scer\YMR262W" "Cele\B0432.8, Cele\Y24F12A.1, Cele\Y37H2A.1, Cele\crn-2" Xtro\tatdn1 "Mmus\Tatdn1, Mmus\Tatdn2, Mmus\Tatdn3" "Hsap\TATDN2, Hsap\TATDN3, Hsap\TATDN1" long lived "germline cell,male" FBgn0022995 ned no endurance http://flybase.org/reports/FBgn0022995 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available ned - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020873 anon-P241 anon-P241 http://flybase.org/reports/FBgn0020873 - gene - - - "2-P241, anon-P241" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,dominant" FBgn0030406 CG1463 - http://flybase.org/reports/FBgn0030406 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - CG1463 "IPR007529:Zinc finger, HIT-type" CG1463 11-Aug-17 DroID_v2017_08 "Drer\znhit3, Drer\znhit6" "Scer\HIT1, Scer\BCD1" Cele\zhit-3 "Xtro\znhit3, Xtro\znhit6" "Mmus\Znhit6, Mmus\Znhit3" "Hsap\ZNHIT6, Hsap\ZNHIT3" "viable,visible" trichogen cell DRSC19603 I 3.095424287 0.443510766 1.178367911 0.48168804 -0.364500751 0.275324612 FBgn0065242 l(2)SH2149 lethal (2) SH2149 http://flybase.org/reports/FBgn0065242 gene - - - "l(2)SH2149, l(2)SH2 2149" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038681 Cyp12a4 Cyp12a4 http://flybase.org/reports/FBgn0038681 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 response to insecticide ; GO:0017085 | inferred from mutant phenotype" - "Cyp12a4, cyp12a4, 12a4, CG6042, P450, CYP12A4" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG6042 11-Aug-17 DroID_v2017_08 "Drer\cyp24a1, Drer\cyp27b1, Drer\cyp11a2, Drer\cyp27a1.4, Drer\cyp11c1, Drer\si:ch211-113j14.1, Drer\zgc:136333, Drer\cyp27a1.2, Drer\cyp27c1, Drer\cyp27a7, Drer\si:dkey-91i10.3" Scer\DIT2 "Cele\cyp-33D1, Cele\ZK177.4, Cele\cyp-35B3, Cele\cyp-44A1" "Xtro\cyp27c1, Xtro\cyp11a1, Xtro\cyp27a1, Xtro\cyp27b1, Xtro\LOC100145331, Xtro\cyp24a1" "Mmus\Cyp24a1, Mmus\Cyp27a1, Mmus\Cyp27b1, Mmus\Cyp11b2, Mmus\Cyp11b1, Mmus\Cyp11a1" "Hsap\CYP24A1, Hsap\CYP27B1, Hsap\CYP27C1, Hsap\CYP11B1, Hsap\CYP27A1, Hsap\CYP11B2, Hsap\CYP11A1" "viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0001688 l(1)ESHS9 lethal (1) ESHS9 http://flybase.org/reports/FBgn0001688 - gene - - - l(1)ESHS9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036772 CG5290 - http://flybase.org/reports/FBgn0036772 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG5290 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG5290 11-Aug-17 DroID_v2017_08 Drer\ttc27 Scer\EMW1 Cele\trd-1 Xtro\ttc27 Mmus\Ttc27 Hsap\TTC27 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0001271 irreB irregular optic chiasma B http://flybase.org/reports/FBgn0001271 - gene - - - irreB - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025942 anon-89Ba anon-89Ba http://flybase.org/reports/FBgn0025942 - gene - - - "89B-ov2.5, anon-89Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage ovary

FBgn0266243 CR44938 - http://flybase.org/reports/FBgn0266243 non_protein_coding_gene - - - "CR44938, lincRNA.736" - CR44938 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036038 defl deflated http://flybase.org/reports/FBgn0036038 protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:24484 snRNA 3'-end processing ; GO:0034472 | inferred from direct assay snRNA processing ; GO:0016180 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay integrator complex ; GO:0032039 | inferred from biological aspect of ancestor with PANTHER:PTN000330295 integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:24484 "CG18176, defl, IntS7, Int7" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR033060:Integrator complex subunit 7" CG18176 11-Aug-17 DroID_v2017_08 Drer\ints7 - Cele\D1043.1 Xtro\ints7 Mmus\Ints7 Hsap\INTS7 "male fertile,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,female fertile,reduced,visible,viable" "dorsal appendage,maternal effect,chorion | maternal effect,anterior crossvein,ectopic,wing,macrochaeta & mesothoracic tergumesg-p127,macrochaeta & mesothoracic tergumarm.PS,mesothoracic tergum,tergite,genitalia,wing vein L5,humeral bristle,adult abdomen" DRSC10300 IE 2.029347656 -2.629531054 0.971239028 -1.867773739 -0.182937955 0.089930885 FBgn0259429 EP-A7 - http://flybase.org/reports/FBgn0259429 gene - - - EP-A7 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0004689 posterior-cell-blister posterior cell blister http://flybase.org/reports/FBgn0004689 - gene - - - "posterior-cell-blister, pcb" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,2nd posterior cell" FBgn0053444 5SrRNA:CR33444 5SrRNA:CR33444 http://flybase.org/reports/FBgn0053444 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33444, 5SrRNA:CR33444" - CR33444 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085592 CG41276 - http://flybase.org/reports/FBgn0085592 protein_coding_gene - - - CG41276 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051041 CG31041 - http://flybase.org/reports/FBgn0051041 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31041 IPR007931:Protein of unknown function DUF725 CG31041 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085322 CG34293 - http://flybase.org/reports/FBgn0085322 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34293 IPR024512:Small subunit of serine palmitoyltransferase-like CG34293 11-Aug-17 DroID_v2017_08 "Drer\sptssb, Drer\sptssa" - Cele\F13H10.8 "Xtro\sptssa, Xtro\sptssb" "Mmus\Sptssb, Mmus\Sptssa" "Hsap\SPTSSB, Hsap\SPTSSA" FBgn0000888 fs(1)M86 female sterile (1) M86 http://flybase.org/reports/FBgn0000888 - gene - - - fs(1)M86 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0037283 CG14658 - http://flybase.org/reports/FBgn0037283 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14658 - CG14658 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0260476 CG30153 - http://flybase.org/reports/FBgn0260476 protein_coding_gene - - - CG30153 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033372 CG13742 - http://flybase.org/reports/FBgn0033372 protein_coding_gene - - - "BcDNA:LD16446, CG13742" - CG13742 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263471 scaRNA:MeU2-48 small Cajal body-specific RNA : MeU2-48 http://flybase.org/reports/FBgn0263471 snoRNA_gene snRNA 2'-O-ribose methylation guide activity ; GO:0030563 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "scaRNA:MeU2-48, mgU2-48, scaRNA:pUf68-a" - CR43586 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038986 sit stuck in traffic http://flybase.org/reports/FBgn0038986 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond cholesterol homeostasis ; GO:0042632 | inferred from mutant phenotype pupal development ; GO:0035209 | inferred from mutant phenotype fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond steroid biosynthetic process ; GO:0006694 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "CG5278, sit" "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG5278 11-Aug-17 DroID_v2017_08 "Drer\elovl7b, Drer\elovl7a, Drer\elovl1b, Drer\elovl4a, Drer\elovl4b, Drer\elovl5, Drer\zgc:101858, Drer\hsd17b8, Drer\dhrs7, Drer\elovl2, Drer\elovl8a, Drer\elovl1a, Drer\elovl8b" "Scer\ELO1, Scer\ELO3, Scer\ELO2" "Cele\dhs-11, Cele\F25D1.5, Cele\Y47G6A.22, Cele\Y47G6A.21, Cele\dhs-25, Cele\ZK829.1, Cele\F28H7.2, Cele\C06E4.3, Cele\dhs-14, Cele\F26D2.15" "Xtro\elovl2, Xtro\elovl5, Xtro\elovl4, Xtro\hsd17b8, Xtro\elovl1, Xtro\cbr4, Xtro\elovl7, Xtro\dhrs7, Xtro\MGC79752" "Mmus\Elovl7, Mmus\Elovl4, Mmus\Cbr4, Mmus\Elovl2, Mmus\H2-Ke6, Mmus\Dhrs7, Mmus\Elovl1, Mmus\Elovl5" "Hsap\ELOVL7, Hsap\ELOVL1, Hsap\ELOVL4, Hsap\ELOVL5, Hsap\CBR4, Hsap\ELOVL2, Hsap\DHRS7, Hsap\HSD17B8" viable FBgn0085263 CG34234 - http://flybase.org/reports/FBgn0085263 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34234 IPR031931:Protein of unknown function DUF4768 CG34234 11-Aug-17 DroID_v2017_08 "Drer\hexa, Drer\hexb" - - Xtro\hexb "Mmus\Hexa, Mmus\Hexb" "Hsap\HEXB, Hsap\HEXA" FBgn0032473 CG5204 - http://flybase.org/reports/FBgn0032473 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "anon-WO0118547.212, CG5204" IPR013087:Zinc finger C2H2-type CG5204 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-269m15.3, Drer\prdm9, Drer\rest, Drer\zfp64" - Cele\C28G1.4 "Xtro\znf142, Xtro\znf462" "Mmus\Zfp335, Mmus\Zfp64, Mmus\Zfp462" "Hsap\ZNF569, Hsap\ZNF335, Hsap\ZNF184, Hsap\ZNF462, Hsap\ZFP64" viable FBgn0035928 CG13310 - http://flybase.org/reports/FBgn0035928 protein_coding_gene - - - CG13310 IPR000859:CUB domain CG13310 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023505 Fas2::Nrg Fas2::Nrg http://flybase.org/reports/FBgn0023505 - engineered_fusion_gene - - - Fas2::Nrg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043968 U5E3 U5E3 http://flybase.org/reports/FBgn0043968 gene - - - U5E3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085790 CR41507 - http://flybase.org/reports/FBgn0085790 pseudogene_attribute - - - CR41507 - CR41507 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028219 l(3)S007902 lethal (3) S007902 http://flybase.org/reports/FBgn0028219 gene - - - "0079/02, l(3)S007902" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0000843 fs(1)M30 female sterile (1) M30 http://flybase.org/reports/FBgn0000843 - gene - - - fs(1)M30 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile chorion FBgn0044008 Su(rst)B188 Su(rst)B188 http://flybase.org/reports/FBgn0044008 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B188, Su(rst)B188" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0085491 CG34462 - http://flybase.org/reports/FBgn0085491 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with UniProtKB:P11734 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG34462, Cpr66Ca, CG7072, DmelCpr66Ca" IPR000618:Insect cuticle protein CG34462 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0085802 18SrRNA:CR41548 18S ribosomal RNA:CR41548 http://flybase.org/reports/FBgn0085802 rRNA_gene - - - "CR41548, 18SrRNA:CR41548" - CR41548 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260999 AGAR-21 Autosomal general anesthetic resistant 21 http://flybase.org/reports/FBgn0260999 gene - - - AGAR-21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0039689 CIA30 "Complex I intermediate-associated protein, 30 kDa" http://flybase.org/reports/FBgn0039689 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:O42636 "mitochondrion organization ; GO:0007005 | inferred from mutant phenotype mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from mutant phenotype mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from mutant phenotype oxidative phosphorylation ; GO:0006119 | inferred from sequence or structural similarity with UniProtKB:Q9Y375 response to hyperoxia ; GO:0055093 | inferred from mutant phenotype mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O42636 response to starvation ; GO:0042594 | inferred from mutant phenotype" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O42636 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:Q9Y375 "CG7598, CI30, CIA30, dCIA30" "IPR013857:NADH:ubiquinone oxidoreductase intermediate-associated protein 30, IPR008979:Galactose-binding domain-like" CG7598 11-Aug-17 DroID_v2017_08 Drer\ndufaf1 - Cele\nuaf-1 Xtro\ndufaf1 Mmus\Ndufaf1 Hsap\NDUFAF1 viable FBgn0058138 CG40138 - http://flybase.org/reports/FBgn0058138 protein_coding_gene - - - CG40138 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024648 l(2)k09502 lethal (2) k09502 http://flybase.org/reports/FBgn0024648 - gene - - - "95/2, l(2)k09502" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043870 nompI no mechanoreceptor potential I http://flybase.org/reports/FBgn0043870 gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - nompI - - 11-Aug-17 DroID_v2017_08 - - - - - - "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective" "wing,leg,macrochaeta,adult antennal nerve" FBgn0028417 Mao Monoamine oxidase http://flybase.net/reports/FBgn0028417.html gene 0008131=primary amine oxidase activity 0005741=mitochondrial outer membrane MAO 11-Aug-17 DroID_v2017_08 FBgn0051448 CG31448 - http://flybase.org/reports/FBgn0051448 protein_coding_gene - - - CG31448 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035575 CG7509 - http://flybase.org/reports/FBgn0035575 protein_coding_gene - - - "tartan/capricious-like, CT1509, CG7509" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG7509 11-Aug-17 DroID_v2017_08 "Drer\lgi2a, Drer\lrrc15, Drer\lgi2b, Drer\lgi1a, Drer\zgc:153913, Drer\lgi1b, Drer\lgi3" - "Cele\lron-11, Cele\iglr-1" "Xtro\lgi1, Xtro\lgi4, Xtro\lrrc15" "Mmus\Lingo3, Mmus\Lrrtm2, Mmus\Lgi3, Mmus\Lgi4, Mmus\Lrrc15, Mmus\Gp5, Mmus\Cpn2, Mmus\Lgi2, Mmus\Lgi1" "Hsap\LRRTM2, Hsap\LGI3, Hsap\LRRC15, Hsap\LGI1, Hsap\LGI4, Hsap\LINGO3, Hsap\LGR5, Hsap\CPN2, Hsap\LGI2, Hsap\GP5" FBgn0026308 agee antenno-glial expressed http://flybase.org/reports/FBgn0026308 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "D5, agee" - - 11-Aug-17 DroID_v2017_08 - - - - - - "grooming behavior defective,recessive" FBgn0004884 bwk bullwinkle http://flybase.org/reports/FBgn0004884 - gene - anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype maintenance of pole plasm mRNA location ; GO:0046594 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - bwk - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,female sterile,visible,recessive,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,maternal effect,lethal" "dorsal appendage,embryo,follicle cell,chorion,wing vein,ectopic,wing,chorion | anterior" FBgn0040591 CG13828 - http://flybase.org/reports/FBgn0040591 protein_coding_gene - - - CG13828 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028668 Vha16-2 Vacuolar H[+] ATPase 16kD subunit 2 http://flybase.org/reports/FBgn0028668 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from sequence model proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000813763" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR002379, InterPro:IPR011555 lysosomal lumen acidification ; GO:0007042 | inferred from biological aspect of ancestor with PANTHER:PTN000813819 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model phagocytosis ; GO:0006909 | inferred from mutant phenotype" "vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000000753 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model" "CG32089, vha16-2, CG7547, Vha16-2" "IPR000245:V-ATPase proteolipid subunit, IPR002379:V-ATPase proteolipid subunit C-like domain, IPR011555:V-ATPase proteolipid subunit C, eukaryotic" CG32089 11-Aug-17 DroID_v2017_08 "Drer\atp6v0ca, Drer\atp6v0cb" "Scer\VMA3, Scer\VMA11" "Cele\vha-3, Cele\vha-2, Cele\vha-1" Xtro\atp6v0c Mmus\Atp6v0c Hsap\ATP6V0C "viable,fertile,visible" mesothoracic tergum FBgn0003445 smp small pallid http://flybase.org/reports/FBgn0003445 - gene - - - smp - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,male fertile,female sterile,body color defective" "macrochaeta,eye" FBgn0250832 Dup99B Ductus ejaculatorius peptide 99B http://flybase.org/reports/FBgn0250832 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR012608 G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with SPR "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay multicellular organism reproduction ; GO:0032504 | inferred from expression pattern regulation of oviposition ; GO:0046662 | traceable author statement negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype oviposition ; GO:0018991 | inferred from mutant phenotype negative regulation of female receptivity ; GO:0007621 | traceable author statement" extracellular space ; GO:0005615 | inferred from direct assay "Dup99B, DUP99B, DUP, CG33495, anon-SAGE:Wang-013" IPR012608:Sex peptide CG33495 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030189 CG2909 - http://flybase.org/reports/FBgn0030189 protein_coding_gene - - - CG2909 IPR032063:Protein of unknown function DUF4804 CG2909 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0266457 CR45082 - http://flybase.org/reports/FBgn0266457 non_protein_coding_gene - - - CR45082 - CR45082 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085694 CG41563 - http://flybase.org/reports/FBgn0085694 protein_coding_gene - - - CG41563 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259584 B2028 - http://flybase.org/reports/FBgn0259584 gene - - - B2028 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible leg FBgn0030648 CG6340 - http://flybase.org/reports/FBgn0030648 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000428218 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from biological aspect of ancestor with PANTHER:PTN000428218" spliceosomal complex ; GO:0005681 | inferred from biological aspect of ancestor with PANTHER:PTN000428218 nucleoplasm ; GO:0005654 | inferred from direct assay CG6340 IPR028124:Small acidic protein-like domain CG6340 11-Aug-17 DroID_v2017_08 "Drer\rsrc2, Drer\rbm25b" - "Cele\ZC262.2, Cele\W04D2.6" Xtro\rsrc2 "Mmus\Rsrc2, Mmus\Rbm25" "Hsap\RSRC2, Hsap\RBM25" "viable,fertile" DRSC19987 K 0.001639136 -1.089947542 -0.017903421 -0.302849359 0.611020067 1.593446838 FBgn0267134 CR45574 - http://flybase.org/reports/FBgn0267134 non_protein_coding_gene - - - "lincRNA.730, CR45574" - CR45574 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026090 CG14812 - http://flybase.org/reports/FBgn0026090 FBgn0062994 protein_coding_gene - negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043154 | inferred from electronic annotation with InterPro:IPR024135 viral genome replication ; GO:0019079 | inferred from electronic annotation with InterPro:IPR024135 cellular response to amino acid stimulus ; GO:0071230 | inferred from mutant phenotype positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype Ragulator complex ; GO:0071986 | inferred from electronic annotation with InterPro:IPR024135 "EG:131F2.3, BcDNA:RE59545, CG14812, dHBXIP" IPR024135:Ragulator complex protein LAMTOR5 CG14812 11-Aug-17 DroID_v2017_08 Drer\lamtor5 - Cele\lmtr-5 Xtro\lamtor5 Mmus\Lamtor5 Hsap\LAMTOR5 viable FBgn0034842 Prosbeta5R1 Proteasome beta5 subunit-related 1 http://flybase.org/reports/FBgn0034842 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | inferred from sequence or structural similarity with SGD:S000006307" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000006307 "proteasome core complex, beta-subunit complex ; GO:0019774 | inferred from sequence or structural similarity with SGD:S000006307" "CG9868, Prosbeta5R1, Prosbeta5R, beta5R1" "IPR000243:Peptidase T1A, proteasome beta-subunit, IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR023333:Proteasome B-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG9868 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-14a17.13, Drer\psmb8f, Drer\psmb11b, Drer\psmb5, Drer\psmb8a" Scer\PRE2 Cele\pbs-5 "Xtro\psmb11, Xtro\psmb8, Xtro\psmb5" "Mmus\Psmb11, Mmus\Psmb8, Mmus\Psmb5" "Hsap\PSMB11, Hsap\PSMB5, Hsap\PSMB8" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0050054 CG30054 - http://flybase.org/reports/FBgn0050054 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000654 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with RGDID:619749 phospholipase C-activating dopamine receptor signaling pathway ; GO:0060158 | inferred from biological aspect of ancestor with PANTHER:PTN000026396 adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with RGDID:619749 heterotrimeric G-protein complex ; GO:0005834 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 "CG30054, GNAQ/11/14" "IPR000654:G-protein alpha subunit, group Q, IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG30054 11-Aug-17 DroID_v2017_08 "Drer\gnav1, Drer\gna11a, Drer\gna15.1, Drer\gnaia, Drer\gnai1, Drer\gna15.4, Drer\gnaq, Drer\gnat2, Drer\gnao1a, Drer\gnai2b, Drer\gna15.2, Drer\gna11b, Drer\gnao1b, Drer\gnat1, Drer\si:ch211-207c7.2, Drer\gnaz, Drer\gna14, Drer\gnai3, Drer\gna14a" "Scer\GPA2, Scer\CIN4, Scer\GPA1" "Cele\gpa-7, Cele\gpa-2, Cele\gpa-3, Cele\goa-1, Cele\gpa-4, Cele\odr-3, Cele\egl-30, Cele\gpa-16, Cele\gpa-1" "Xtro\gnaq, Xtro\gna11, Xtro\gnat2, Xtro\gnat1, Xtro\gna14, Xtro\gnai3, Xtro\gnao1, Xtro\gnai1, Xtro\gnai2, Xtro\gna15" "Mmus\Gnat1, Mmus\Gna14, Mmus\Gnai3, Mmus\Gnat3, Mmus\Gna15, Mmus\Gnaz, Mmus\Gnat2, Mmus\Gnai1, Mmus\Gnao1, Mmus\Gna11, Mmus\Gnaq, Mmus\Gnai2" "Hsap\GNA15, Hsap\GNAI3, Hsap\GNAZ, Hsap\GNAQ, Hsap\GNAT2, Hsap\GNA11, Hsap\GNA14, Hsap\GNAI2, Hsap\GNAT1, Hsap\GNAT3, Hsap\GNAO1, Hsap\GNAI1" viable FBgn0051491 tRNA:Gly-TCC-1-2 transfer RNA:Glycine-TCC 1-2 http://flybase.org/reports/FBgn0051491 tRNA_gene GGA codon-amino acid adaptor activity ; GO:0033463 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033463 cytosol ; GO:0005829 | inferred by curator from GO:0033463 "AE002699.trna3-GlyTCC, tRNA:G:TCC:AE002699-a, CR31491, chr3R.trna76-GlyTCC, tRNA-Gly-TCC-1-2, tRNA:Gly-TCC-1-2, tRNA:CR31491, GGA" - CR31491 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014211 l(2)31Aa lethal (2) 31Aa http://flybase.org/reports/FBgn0014211 - gene - - - l(2)31Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265715 CR44522 - http://flybase.org/reports/FBgn0265715 non_protein_coding_gene - - - "incRNA.450, CR44522, lincRNA.450" - CR44522 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265011 Np Notopleural http://flybase.org/reports/FBgn0265011 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "Np, CG34350, SP59, CG11824, CG8181, np" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR033116:Serine proteases, trypsin family, serine active site" CG34350 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-238d18.3, Drer\mst1, Drer\ela2l, Drer\ctrl, Drer\zgc:112285, Drer\zgc:112160, Drer\ela2, Drer\tmprss9, Drer\zgc:92511, Drer\zgc:112302, Drer\hgfa, Drer\zgc:171592, Drer\zmp:0000001114, Drer\ela3l, Drer\zgc:92745, Drer\si:dkey-57c15.4, Drer\zgc:92041, Drer\LOC562139, Drer\zgc:112368, Drer\zgc:154142, Drer\ctrb1, Drer\zgc:55888, Drer\st14a" - "Cele\svh-1, Cele\try-1" "Xtro\ctrb2, Xtro\tmprss4, Xtro\ctrb1, Xtro\LOC100135144, Xtro\cela2a, Xtro\cela3a, Xtro\prss29" "Mmus\St14, Mmus\Ctrl, Mmus\Gzma, Mmus\Cela2a, Mmus\Cela3b, Mmus\Cela1, Mmus\Tmprss13, Mmus\Ctrb1, Mmus\Gzmm, Mmus\Cela3a, Mmus\Tmprss15, Mmus\Ctrc" "Hsap\CELA2A, Hsap\TMPRSS13, Hsap\CELA1, Hsap\GZMA, Hsap\GZMM, Hsap\CELA3B, Hsap\CELA3A, Hsap\CTRC, Hsap\CTRB2, Hsap\CTRL, Hsap\CTRB1, Hsap\ST14, Hsap\CELA2B" FBgn0005681 ire irregular eye http://flybase.org/reports/FBgn0005681 - gene - compound eye development ; GO:0048749 | inferred from mutant phenotype - ire - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "eye,ommatidium,photoreceptor cell R7,eye photoreceptor cell" FBgn0065349 l(2)SH1808 lethal (2) SH1808 http://flybase.org/reports/FBgn0065349 gene - - - "l(2)SH1808, l(2)SH2 1808" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020783 sept seven pentacosene http://flybase.org/reports/FBgn0020783 - gene - pheromone metabolic process ; GO:0042810 | inferred from mutant phenotype - sept - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267659 CR45997 - http://flybase.org/reports/FBgn0267659 non_protein_coding_gene - - - "CR45997, lincRNA.339" - CR45997 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022005 l(2)k09238 lethal (2) k09238 http://flybase.org/reports/FBgn0022005 - gene - - - l(2)k09238 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036274 CG4328 - http://flybase.org/reports/FBgn0036274 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" - CG4328 "IPR001356:Homeobox domain, IPR001781:Zinc finger, LIM-type, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site" CG4328 11-Aug-17 DroID_v2017_08 "Drer\lmx1bb, Drer\lmx1al, Drer\pou3f3b, Drer\pou3f2b, Drer\hoxb7a, Drer\lmx1ba, Drer\pou3f1, Drer\lmx1a, Drer\hoxa9b" Scer\YOX1 "Cele\php-3, Cele\ceh-6, Cele\lim-6" "Xtro\lmx1b.2, Xtro\hoxa7, Xtro\lmx1a, Xtro\lmx1b.1, Xtro\pou3f1" "Mmus\Pou3f1, Mmus\Pou3f3, Mmus\Pou3f4, Mmus\Lmx1b, Mmus\Pou3f2, Mmus\Lmx1a, Mmus\Hoxa7, Mmus\Hoxb7" "Hsap\LMX1A, Hsap\POU3F3, Hsap\HOXB7, Hsap\POU3F1, Hsap\POU3F4, Hsap\HOXA7, Hsap\POU3F2, Hsap\LMX1B" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC23146 K -1.818202919 -0.03893374 FBgn0263518 mir-4975 mir-4975 stem loop http://flybase.org/reports/FBgn0263518 miRNA_gene - - - "mir-4975, CR43503, dme-mir-4975" - CR43503 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262400 mir-287 mir-287 stem loop http://flybase.org/reports/FBgn0262400 miRNA_gene - - - "mir-287, CR42939, miR-287, Mir-287, CR33603" - CR42939 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039686 CG15506 - http://flybase.org/reports/FBgn0039686 protein_coding_gene - - - CG15506 - CG15506 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0012032 1731\RTase 1731-repetitive-element reverse transcriptase http://flybase.org/reports/FBgn0012032 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "ORF2, 1731\RTase" "IPR013103:Reverse transcriptase, RNA-dependent DNA polymerase, IPR001584:Integrase, catalytic core, IPR025724:GAG-pre-integrase domain, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037430 Osi20 Osiris 20 http://flybase.org/reports/FBgn0037430 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG15188, Osi20" IPR012464:Protein of unknown function DUF1676 CG15188 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0046882 Lar::Ptp69D Lar::Ptp69D http://flybase.org/reports/FBgn0046882 engineered_fusion_gene - - - Lar::Ptp69D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259849 Su(Ste):CR42418 Su(Ste):CR42418 http://flybase.org/reports/FBgn0259849 non_protein_coding_gene - - - "Su(Ste):CR42418, CR42418" - CR42418 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035730 CG17744 - http://flybase.org/reports/FBgn0035730 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17744 - CG17744 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027873 Cpsf100 Cleavage and polyadenylation specificity factor 100 http://flybase.org/reports/FBgn0027873 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSU4 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with UniProtKB:Q10568 mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from sequence or structural similarity with UniProtKB:Q10568 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from direct assay mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from sequence or structural similarity with UniProtKB:Q10568 "BcDNA:LD14168, Cpsf100, CPSF100, CG1957, CPSF-100" "IPR001279:Metallo-beta-lactamase, IPR011108:Zn-dependent metallo-hydrolase, RNA specificity domain, IPR025069:Cleavage and polyadenylation specificity factor 2, C-terminal, IPR027075:Cleavage and polyadenylation specificity factor subunit 2, IPR022712:Beta-Casp domain" CG1957 11-Aug-17 DroID_v2017_08 Drer\cpsf2 "Scer\YSH1, Scer\CFT2" Cele\cpsf-2 Xtro\cpsf2 Mmus\Cpsf2 Hsap\CPSF2 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC14146 I 1.627040655 1.993760598 -0.03319487 -0.553908201 -0.530139553 -0.183899081 FBgn0038207 CG14356 - http://flybase.org/reports/FBgn0038207 protein_coding_gene - - - CG14356 - CG14356 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0013721 per::Dsim\per per::Dsim\per http://flybase.org/reports/FBgn0013721 - engineered_fusion_gene - - - per::Dsim\per - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051636 CG31636 - http://flybase.org/reports/FBgn0051636 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "CG13770, CG31636" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG31636 11-Aug-17 DroID_v2017_08 "Drer\sec14l7, Drer\ttpal, Drer\ttpa, Drer\rlbp1a, Drer\rlbp1b, Drer\clvs2, Drer\sec14l8" "Scer\SEC14, Scer\SFH5, Scer\YKL091C" - "Xtro\ttpa, Xtro\rlbp1, Xtro\sec14l5, Xtro\clvs2, Xtro\clvs1, Xtro\sec14l3, Xtro\mospd2, Xtro\ttpal, Xtro\sec14l1" "Mmus\Sec14l5, Mmus\Clvs1, Mmus\Sec14l1, Mmus\Sec14l3, Mmus\Clvs2, Mmus\Sec14l2, Mmus\Sec14l4, Mmus\Rlbp1, Mmus\Ttpal, Mmus\Ttpa" "Hsap\SEC14L5, Hsap\TTPA, Hsap\SEC14L2, Hsap\RLBP1, Hsap\SEC14L1, Hsap\CLVS2, Hsap\SEC14L6, Hsap\CLVS1, Hsap\TTPAL, Hsap\SEC14L4, Hsap\SEC14L3" viable DRSC24911 K 0.062480871 -0.35094369 -0.719603161 0.341463281 0.128143483 1.55877849 FBgn0001398 l(1)2Ea lethal (1) 2Ea http://flybase.org/reports/FBgn0001398 - gene - - - "l(1)JA127, N7, l70, JA127, N3, l(1)N7, l(1)N5, l(1)2Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032393 CG12264 - http://flybase.org/reports/FBgn0032393 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR010240 cysteine desulfurase activity ; GO:0031071 | inferred from electronic annotation with InterPro:IPR010240 cystathionine gamma-lyase activity ; GO:0004123 | inferred from sequence or structural similarity with UniProtKB:Q9Y697 [2Fe-2S] cluster assembly ; GO:0044571 | inferred from electronic annotation with InterPro:IPR010240 iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with UniProtKB:Q9Y697 alanine biosynthetic process ; GO:0006523 | inferred from sequence or structural similarity with UniProtKB:Q9Y697 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9Y697 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9Y697 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG12264, CG12264-PA" "IPR000192:Aminotransferase class V domain, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR016454:Cysteine desulfurase, IPR010240:Cysteine desulfurase IscS, IPR020578:Aminotransferase class-V, pyridoxal-phosphate binding site, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG12264 11-Aug-17 DroID_v2017_08 "Drer\scly, Drer\nfs1" Scer\NFS1 Cele\B0205.6 "Xtro\nfs1, Xtro\scly" "Mmus\Scly, Mmus\Nfs1" "Hsap\NFS1, Hsap\SCLY" "viable,locomotor rhythm defective" FBgn0001940 l(2)26Aa lethal (2) 26Aa http://flybase.org/reports/FBgn0001940 - gene - - - "l[x], l(2)26Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033368 CG13743 - http://flybase.org/reports/FBgn0033368 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 - CG13743 "IPR013057:Amino acid transporter, transmembrane domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG13743 11-Aug-17 DroID_v2017_08 "Drer\slc38a3a, Drer\slc38a5a, Drer\slc38a4, Drer\slc38a8a, Drer\slc38a8b, Drer\slc38a6, Drer\slc38a5b, Drer\slc38a9, Drer\slc38a11, Drer\slc38a7, Drer\slc38a2, Drer\LOC100536170, Drer\slc38a10, Drer\slc38a3b" "Scer\AVT5, Scer\AVT7, Scer\AVT6, Scer\AVT2" Cele\Y51F10.4 "Xtro\slc38a6, Xtro\slc38a11, Xtro\slc38a7, Xtro\slc38a2, Xtro\slc38a3, Xtro\slc38a9, Xtro\slc38a10, Xtro\slc38a5" "Mmus\Slc38a4, Mmus\Slc38a6, Mmus\Slc38a2, Mmus\Slc38a3, Mmus\Slc38a8, Mmus\Slc38a10, Mmus\Slc38a11, Mmus\Slc38a5, Mmus\Slc38a1, Mmus\Slc38a7, Mmus\Slc38a9" "Hsap\SLC38A1, Hsap\SLC38A4, Hsap\SLC38A10, Hsap\SLC38A7, Hsap\SLC38A6, Hsap\SLC38A2, Hsap\SLC38A8, Hsap\SLC38A5, Hsap\SLC38A3, Hsap\SLC38A9, Hsap\SLC38A11" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265378 CR44319 - http://flybase.org/reports/FBgn0265378 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44319, CR44319" - CR44319 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260233 CG42507 - http://flybase.org/reports/FBgn0260233 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42507 - CG42507 11-Aug-17 DroID_v2017_08 - "Scer\PCL7, Scer\PHO80" - - - - FBgn0027351 anon-93Bb anon-93Bb http://flybase.org/reports/FBgn0027351 - gene - - - anon-93Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065096 snmRNA:359 small non-messenger RNA 359 http://flybase.org/reports/FBgn0065096 non_protein_coding_gene - - - "Dm-359, CR33712, snmRNA:359" - CR33712 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022297 l(1)M37.2 lethal (1) M37.2 http://flybase.org/reports/FBgn0022297 - gene - - - "M37.2, l(1)M37.2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038815 CG5466 - http://flybase.org/reports/FBgn0038815 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG5466 "IPR029021:Protein-tyrosine phosphatase-like, IPR022207:Genetic suppressor element-like" CG5466 11-Aug-17 DroID_v2017_08 - - Cele\eya-1 - Mmus\Aes Hsap\AES "viable,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0026313 X11L X11L http://flybase.org/reports/FBgn0026313 "FBgn0030848, FBgn0030849" protein_coding_gene cell adhesion molecule binding ; GO:0050839 | inferred from physical interaction with rst compound eye development ; GO:0048749 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle docking ; GO:0016081 | non-traceable author statement protein localization to membrane ; GO:0072657 | inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement synaptic vesicle targeting ; GO:0016080 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay "CG5678, Dmint, dX11L, CG5675, X11, Mint, MINT, X11L, X11Lalpha, dX11, x11Lalpha, Dmint1, X11/Mint, X11-like, x11/Mint, dX11Lalpha, dX11/Mint" "IPR001478:PDZ domain, IPR006020:PTB/PI domain, IPR011993:PH domain-like" CG5675 11-Aug-17 DroID_v2017_08 "Drer\apba2b, Drer\lnx1, Drer\grip1, Drer\si:ch73-40i7.5, Drer\inadl, Drer\grid2ipa, Drer\apba2a, Drer\apba1b, Drer\il16, Drer\dlg5a, Drer\slc9a3r1, Drer\pdzd7b, Drer\pard3bb, Drer\apba1a, Drer\grip2b, Drer\si:dkey-92i15.4" - Cele\lin-10 "Xtro\lnx1, Xtro\grid2ip, Xtro\dlg5, Xtro\grip1, Xtro\apba2, Xtro\grip2" "Mmus\Pdzph1, Mmus\Grip2, Mmus\Pdzd11, Mmus\Mpdz, Mmus\Apba1, Mmus\Patj, Mmus\Dlg5, Mmus\Pdzd2, Mmus\Ush1c, Mmus\Apba2, Mmus\Apba3, Mmus\Il16, Mmus\Grid2ip, Mmus\Grip1, Mmus\Lnx1, Mmus\Grasp" "Hsap\APBA1, Hsap\GRID2IP, Hsap\GRASP, Hsap\MPDZ, Hsap\IL16, Hsap\APBA2, Hsap\PARD3B, Hsap\FRMPD2, Hsap\USH1C, Hsap\PATJ, Hsap\DLG5, Hsap\APBA3, Hsap\GRIP1, Hsap\LNX1, Hsap\PDZD2" "visible,increased cell death,viable,fertile" "ommatidium,interommatidial bristle,rhabdomere | ectopicMZ1369,four cone-cell ommatidial precursor cluster,primary pigment cell,ommatidial precursor cluster,eye,eye disc,rhabdomereGMR.PF,lamina neuropil,medulla neuropil" DRSC19958 I 0.928859217 1.661872811 0.563892156 0.639627738 -0.308454285 0.464484843 FBgn0028473 Non1 Novel nucleolar protein 1 http://flybase.org/reports/FBgn0028473 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006073, InterPro:IPR010674, InterPro:IPR031167" mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay "BcDNA:LD23830, CG30341, CG8801, Non1, LD23830" "IPR005225:Small GTP-binding protein domain, IPR006073:GTP binding domain, IPR010674:Nucleolar GTP-binding protein 1, Rossman-fold domain, IPR012973:NOG, C-terminal, IPR024926:Nucleolar GTP-binding protein 1, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031167:OBG-type guanine nucleotide-binding (G) domain" CG8801 11-Aug-17 DroID_v2017_08 Drer\gtpbp4 Scer\NOG1 Cele\nog-1 Xtro\gtpbp4 Mmus\Gtpbp4 Hsap\GTPBP4 FBgn0002701 mdl male diplolethal http://flybase.org/reports/FBgn0002701 - gene - - - mdl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266497 s-123.2 - http://flybase.org/reports/FBgn0266497 gene - - - s-123.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267788 CR46119 - http://flybase.org/reports/FBgn0267788 non_protein_coding_gene - - - CR46119 - CR46119 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0281843 T:nls-Ctif - http://flybase.org/reports/FBgn0281843 engineered_foreign_region - - - T:nls-Ctif - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002325 l(3)86Fd lethal (3) 86Fd http://flybase.org/reports/FBgn0002325 - gene - - - "l(3)ck4, l(3)86Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0064138 stalker stalker http://flybase.org/reports/FBgn0064138 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "stl, stalker" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032401 Plzf Promyelocytic leukemia zinc finger http://flybase.org/reports/FBgn0032401 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype Ras protein signal transduction ; GO:0007265 | inferred from genetic interaction with Ras85D - "CG6792, cg6792, PLZF, dPLZF, Plzf" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type" CG6792 11-Aug-17 DroID_v2017_08 "Drer\LOC103911016, Drer\LOC100330167, Drer\zbtb46, Drer\zbtb10, Drer\LOC100333031, Drer\patz1, Drer\LOC799968, Drer\si:dkey-34m19.3, Drer\si:ch73-299h12.9, Drer\si:ch211-241b2.4, Drer\wu:fe17e08, Drer\zbtb14, Drer\znf131, Drer\si:ch211-236k19.4, Drer\zgc:112998, Drer\zbtb18, Drer\si:dkey-261j4.4, Drer\zgc:66448, Drer\zbtb24, Drer\zbtb17, Drer\zbtb7a, Drer\si:ch211-198a12.6, Drer\LOC100537317, Drer\zbtb49, Drer\zgc:165514, Drer\LOC108179164, Drer\im:7141269, Drer\si:ch73-40a17.4, Drer\bcl6ab, Drer\si:dkey-261j4.5, Drer\LOC101883230, Drer\zbtb8a, Drer\si:dkey-262g12.3, Drer\si:dkey-30k6.5, Drer\zgc:165515, Drer\si:ch211-276c2.4, Drer\LOC100538142, Drer\znf143a, Drer\drl, Drer\si:dkey-261j4.3, Drer\zbtb8b, Drer\LOC101883594, Drer\zgc:171673, Drer\si:ch211-155e24.3, Drer\LOC103909987, Drer\si:ch211-222k6.2, Drer\LOC560148" Scer\AZF1 "Cele\Y56A3A.28, Cele\eor-1, Cele\che-1, Cele\scrt-1, Cele\sdz-12, Cele\row-1, Cele\Y48G8AL.10" "Xtro\zbtb7c, Xtro\zbtb26, Xtro\hic1, Xtro\zbtb40, Xtro\zbtb47, Xtro\gzf1, Xtro\zbtb41, Xtro\zbtb14, Xtro\hic2" "Mmus\Zfp131, Mmus\Zbtb24, Mmus\Zbtb7b, Mmus\Zbtb7a, Mmus\Zbtb46, Mmus\Zbtb41, Mmus\Zbtb48, Mmus\Gzf1, Mmus\Zbtb38, Mmus\Zbtb26, Mmus\Zbtb44, Mmus\Bcl6b, Mmus\Zbtb2, Mmus\Patz1, Mmus\Mynn, Mmus\Zbtb7c, Mmus\Zfp637, Mmus\Zbtb8b, Mmus\Zbtb49, Mmus\Zbtb6, Mmus\Zfp523, Mmus\Zfp853, Mmus\Zbtb18, Mmus\Zbtb17, Mmus\Zbtb14, Mmus\Zbtb8a, Mmus\Zfp143" "Hsap\ZBTB38, Hsap\ZBTB42, Hsap\ZBTB14, Hsap\ZBTB2, Hsap\ZBTB48, Hsap\ZBTB41, Hsap\ZBTB25, Hsap\ZBTB46, Hsap\MYNN, Hsap\ZBTB26, Hsap\ZBTB18, Hsap\ZNF32, Hsap\ZBTB11, Hsap\ZNF131, Hsap\ZBTB10, Hsap\ZBTB49, Hsap\ZBTB44, Hsap\PATZ1, Hsap\ZNF853, Hsap\ZBTB17, Hsap\ZBTB8B, Hsap\ZBTB7B, Hsap\ZBTB8A, Hsap\GZF1, Hsap\ZNF143, Hsap\ZBTB24, Hsap\ZBTB6, Hsap\ZBTB43, Hsap\ZBTB7A, Hsap\ZBTB7C, Hsap\BCL6B" "partially lethal - majority die,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile" "wing vein,ectopic,supernumerary" DRSC02994 I 1.577750689 1.07770993 0.052826697 0.85433068 -0.126567889 -0.114137754 FBgn0263530 mir-4917 mir-4917 stem loop http://flybase.org/reports/FBgn0263530 miRNA_gene - - - "mir-4917, dme-mir-4917, CR43515" - CR43515 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033030 CG1294 - http://flybase.org/reports/FBgn0033030 protein_coding_gene - - - CG1294 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005714 l(1)TK117 lethal (1) TK117 http://flybase.org/reports/FBgn0005714 - gene - - - "l117, l(1)TK117" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0034742 CG4294 - http://flybase.org/reports/FBgn0034742 protein_coding_gene - - - "FBgn0034742, CG4294" IPR019607:Putative zinc-finger domain CG4294 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028685 Rpt4 Regulatory particle triple-A ATPase 4 http://flybase.org/reports/FBgn0028685 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 RNA polymerase I regulatory region sequence-specific DNA binding ; GO:0001163 | inferred from direct assay TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ATPase activity ; GO:0016887 | inferred from sequence model" positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter ; GO:1901838 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000005785 microtubule associated complex ; GO:0005875 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9553 inferred from direct assay nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from direct assay" "p42D, Dm_Rpt4b, Dm_Rpt4a, Dmp42D, CG3455, l(1)G0345, l(1)G0227, l(1)G0114, Rpt4, S10b" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3455 11-Aug-17 DroID_v2017_08 "Drer\psmc6, Drer\psmc5, Drer\wdr12, Drer\psmc2" Scer\RPT4 "Cele\rpt-4, Cele\rpt-6, Cele\F56F11.4" "Xtro\psmc6, Xtro\psmc5, Xtro\psmc2, Xtro\wdr12" "Mmus\Wdr12, Mmus\Psmc6, Mmus\Psmc2, Mmus\Psmc5" "Hsap\WDR12, Hsap\PSMC6, Hsap\PSMC5, Hsap\PSMC2" "large body,lethal,recessive,small body,dominant,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC18713 IEK -3.028558953 -3.339096891 -1.185420791 -1.548624083 3.395993992 0.593456199 FBgn0040973 CG16824 - http://flybase.org/reports/FBgn0040973 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG16824 IPR015157:Translation machinery associated TMA7 CG16824 11-Aug-17 DroID_v2017_08 Drer\tma7 Scer\TMA7 Cele\F49C12.11 Xtro\tma7 Mmus\Tma7 Hsap\TMA7 FBgn0019739 l(1)91-2 lethal (1) 91-2 http://flybase.org/reports/FBgn0019739 - gene - - - l(1)91-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266847 CR45309 - http://flybase.org/reports/FBgn0266847 non_protein_coding_gene - - - CR45309 - CR45309 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283525 l(2)10685 lethal (2) 10685 http://flybase.org/reports/FBgn0283525 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from biological aspect of ancestor with PANTHER:PTN000516075 rRNA methylation ; GO:0031167 | inferred from biological aspect of ancestor with PANTHER:PTN000516152 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from biological aspect of ancestor with PANTHER:PTN000516152 "l(2)10685, anon-WO0118547.81, CG4749" "IPR001678:SAM-dependent methyltransferase RsmB/NOP2-type, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR023267:RNA (C5-cytosine) methyltransferase" CG4749 11-Aug-17 DroID_v2017_08 "Drer\nsun2, Drer\nsun4, Drer\nsun3" "Scer\NOP2, Scer\NCL1" Cele\nsun-4 "Xtro\nsun4, Xtro\nsun2, Xtro\nsun3, Xtro\LOC101734691" "Mmus\Nsun4, Mmus\Nsun2, Mmus\Nsun3" "Hsap\NSUN2, Hsap\NSUN3, Hsap\NSUN4" "lethal,recessive" FBgn0011123 l(1)Q85 lethal (1) Q85 http://flybase.org/reports/FBgn0011123 FBgn0010210 gene - - - l(1)Q85 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000083 AnxB9 Annexin B9 http://flybase.org/reports/FBgn0000083 - protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001464, InterPro:IPR018252, InterPro:IPR018502 spectrin binding ; GO:0030507 | inferred from physical interaction with kst actin binding ; GO:0003779 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with kst calcium-dependent phospholipid binding ; GO:0005544 | inferred from sequence or structural similarity with AnxB10" "endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype maintenance of cell polarity ; GO:0030011 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap regulation of multivesicular body size involved in endosome transport ; GO:0010797 | inferred from mutant phenotype basolateral protein localization ; GO:0061467 | inferred from direct assay" endomembrane system ; GO:0012505 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "CG5730, AnxB9, Ann, Anx B9, annexin, AnnIX, ANXB9" "IPR018252:Annexin repeat, conserved site, IPR018502:Annexin repeat, IPR001464:Annexin" CG5730 11-Aug-17 DroID_v2017_08 "Drer\anxa3a, Drer\zgc:101785, Drer\anxa11a, Drer\zgc:110283, Drer\anxa3b, Drer\anxa1a, Drer\anxa2b, Drer\anxa4, Drer\anxa1c, Drer\anxa1b, Drer\anxa13l, Drer\prnprs3, Drer\anxa11b, Drer\LOC103908630, Drer\anxa6, Drer\anxa5a, Drer\anxa13, Drer\anxa2a, Drer\anxa5b" - "Cele\nex-3, Cele\nex-1, Cele\nex-4, Cele\nex-2" "Xtro\anxa7, Xtro\anxa2, Xtro\anxa4, Xtro\anxa13, Xtro\anxa6, Xtro\anxa3, Xtro\anxa5, Xtro\anxa11, Xtro\anxa8, Xtro\anxa1" "Mmus\Anxa6, Mmus\Anxa10, Mmus\Anxa7, Mmus\Anxa1, Mmus\Anxa4, Mmus\Anxa2, Mmus\Anxa3, Mmus\Anxa11, Mmus\Anxa8, Mmus\Anxa9, Mmus\Anxa5" "Hsap\ANXA11, Hsap\ANXA4, Hsap\ANXA2, Hsap\ANXA5, Hsap\ANXA8, Hsap\ANXA3, Hsap\ANXA6, Hsap\ANXA8L1, Hsap\ANXA10, Hsap\ANXA1, Hsap\ANXA9, Hsap\ANXA13, Hsap\ANXA7" viable FBgn0027322 l(1)G0046 lethal (1) G0046 http://flybase.org/reports/FBgn0027322 - gene - - - l(1)G0046 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0051713 Apf diadenosine tetraphosphate hydrolase http://flybase.org/reports/FBgn0051713 protein_coding_gene bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity ; GO:0004081 | inferred from sequence or structural similarity with WB:WBGene00003581 - cellular_component ; GO:0005575 | no biological data available "CG31713, Apf, IP04585" "IPR000086:NUDIX hydrolase domain, IPR003565:Bis(5'-nucleosyl)-tetraphosphatase, IPR015797:NUDIX hydrolase domain-like, IPR020084:NUDIX hydrolase, conserved site" CG31713 11-Aug-17 DroID_v2017_08 "Drer\nudt2, Drer\nudt4a" Scer\DDP1 Cele\ndx-4 "Xtro\LOC101734499, Xtro\nudt2" "Mmus\Nudt10, Mmus\Nudt2, Mmus\Nudt11, Mmus\Nudt3, Mmus\Nudt4" "Hsap\NUDT11, Hsap\NUDT2, Hsap\NUDT10" "viable,fertile" FBgn0026403 Ndg Nidogen/entactin http://flybase.org/reports/FBgn0026403 "FBgn0033509, FBgn0046316" protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" cell-matrix adhesion ; GO:0007160 | inferred from electronic annotation with InterPro:IPR003886 basement membrane ; GO:0005604 | inferred from sequence or structural similarity "CG12908, ndg, CT32053, BEST:CK00552, Ndg" "IPR018097:EGF-like calcium-binding, conserved site, IPR000033:LDLR class B repeat, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR003886:NIDO domain, IPR006605:G2 nidogen/fibulin G2F, IPR009017:Green fluorescent protein, IPR013032:EGF-like, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR009030:Growth factor receptor cysteine-rich domain, IPR024731:EGF domain" CG12908 11-Aug-17 DroID_v2017_08 "Drer\wu:fb77a09, Drer\egf, Drer\nid2b, Drer\nid1a" "Scer\APM3, Scer\APM2, Scer\APM1" "Cele\B0393.5, Cele\eat-20, Cele\nid-1" "Xtro\nid2, Xtro\nid1" "Mmus\Smoc1, Mmus\Smoc2, Mmus\Nid1, Mmus\Nid2" "Hsap\NID1, Hsap\SMOC2, Hsap\LRP5L, Hsap\SMOC1, Hsap\NID2" viable FBgn0086724 GiM Genetic interactor of Moesin http://flybase.org/reports/FBgn0086724 gene - - - "GiM, GIM" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019747 l(1)827 lethal (1) 827 http://flybase.org/reports/FBgn0019747 - gene - - - l(1)827 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051207 CG31207 - http://flybase.org/reports/FBgn0051207 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CG7096, CG31207, CG7096-N" IPR010562:Haemolymph juvenile hormone binding CG31207 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029930 CG12541 - http://flybase.org/reports/FBgn0029930 protein_coding_gene - - - CG12541 "IPR032073:Fibronectin type III domain-containing protein 5, C-terminal domain" CG12541 11-Aug-17 DroID_v2017_08 "Drer\fndc4b, Drer\fndc5b, Drer\fndc5a, Drer\fndc4a" - - Xtro\fndc4 "Mmus\Fndc5, Mmus\Fndc4" "Hsap\FNDC5, Hsap\FNDC4" "viable,visible" "chaeta,supernumerary" FBgn0002262 l(3)69Aa lethal (3) 69Aa http://flybase.org/reports/FBgn0002262 - gene - - - "rsg24, l(3)rsg24, l(3)69Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058212 CG40212 - http://flybase.org/reports/FBgn0058212 protein_coding_gene - - - CG40212 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030685 Graf GTPase regulator associated with FAK http://flybase.org/reports/FBgn0030685 protein_coding_gene phospholipid binding ; GO:0005543 | inferred from sequence or structural similarity with HGNC:17073 GTPase activator activity ; GO:0005096 | inferred from sequence model "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 Rho protein signal transduction ; GO:0007266 | inferred from sequence model" cellular_component ; GO:0005575 | no biological data available "CG8948, D-Graf, Graf, Q9VXQ2_DROME" "IPR000198:Rho GTPase-activating protein domain, IPR001452:SH3 domain, IPR001849:Pleckstrin homology domain, IPR008936:Rho GTPase activation protein, IPR011993:PH domain-like, IPR027267:Arfaptin homology (AH) domain/BAR domain" CG8948 11-Aug-17 DroID_v2017_08 "Drer\LOC569534, Drer\arhgap29a, Drer\arhgap15, Drer\si:ch211-253h3.1, Drer\arhgap10, Drer\chn2, Drer\ophn1, Drer\arhgap42a" "Scer\BEM3, Scer\BEM2, Scer\RGA2" "Cele\T04C9.1, Cele\chin-1, Cele\spv-1, Cele\rga-1" "Xtro\arhgap10, Xtro\ophn1, Xtro\arhgap26, Xtro\abr, Xtro\arhgap24" "Mmus\Arhgap26, Mmus\Arhgap29, Mmus\Gm5820, Mmus\Abr, Mmus\Arhgap10, Mmus\Arhgap42, Mmus\Chn2, Mmus\Ophn1, Mmus\Arhgap15, Mmus\Chn1" "Hsap\ARHGAP15, Hsap\OPHN1, Hsap\ARHGAP42, Hsap\ARHGAP10, Hsap\ARHGAP29, Hsap\ARHGAP26, Hsap\ABR, Hsap\CHN2, Hsap\CHN1" "viable,fertile" FBgn0044863 MMS-4 MMS-4 http://flybase.org/reports/FBgn0044863 gene - - - MMS-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0032230 lft lowfat http://flybase.org/reports/FBgn0032230 protein_coding_gene - autophagosome maturation ; GO:0097352 | inferred from biological aspect of ancestor with PANTHER:PTN001579556 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay subapical complex ; GO:0035003 | inferred from direct assay "lft, CG13139, Lft" IPR029270:Limb expression 1 CG13139 11-Aug-17 DroID_v2017_08 "Drer\lix1, Drer\lix1l" - "Cele\nspc-7, Cele\nspc-5, Cele\nspc-2, Cele\nspc-4, Cele\nspc-1, Cele\nspc-3, Cele\nspc-20, Cele\nspc-9, Cele\nspc-6" "Xtro\lix1, Xtro\lix1l" "Mmus\Lix1l, Mmus\Lix1" "Hsap\LIX1, Hsap\LIX1L" "viable,fertile,visible,recessive" "wing,wing blade,wing disc,posterior compartment" FBgn0014931 CG2678 - http://flybase.org/reports/FBgn0014931 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement" "dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 nucleus ; GO:0005634 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay "B, anon-84Eb, CG2678" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG2678 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-216l23.1, Drer\wu:fe05a04, Drer\zbtb48, Drer\si:ch211-241b2.4" "Scer\ZAP1, Scer\PZF1" "Cele\klu-2, Cele\klf-1, Cele\M03D4.4, Cele\Y55F3AM.14, Cele\klu-1, Cele\ztf-14" Xtro\znf423 "Mmus\Zbtb25, Mmus\Zbtb48, Mmus\Zfp810, Mmus\Zfp189, Mmus\Zkscan2, Mmus\Zfp423, Mmus\Zscan20" "Hsap\ZNF37A, Hsap\ZNF560, Hsap\ZNF423, Hsap\ZBTB48, Hsap\ZSCAN20, Hsap\ZSCAN32, Hsap\ZNF449, Hsap\ZKSCAN2, Hsap\ZSCAN29" "female fertile,viable" FBgn0032503 CG16825 - http://flybase.org/reports/FBgn0032503 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT09390, CG16825" - CG16825 11-Aug-17 DroID_v2017_08 - - Cele\xbx-6 - - - viable FBgn0266565 CR45104 - http://flybase.org/reports/FBgn0266565 non_protein_coding_gene - - - "CR45104, lincRNA.803" - CR45104 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022210 l(2)k04003 lethal (2) k04003 http://flybase.org/reports/FBgn0022210 - gene - - - l(2)k04003 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034835 CG3092 - http://flybase.org/reports/FBgn0034835 protein_coding_gene ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex III biogenesis ; GO:0097033 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 protein insertion into mitochondrial membrane from inner side ; GO:0032979 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 inner mitochondrial membrane organization ; GO:0007007 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex IV biogenesis ; GO:0097034 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 "anon-WO0140519.90, CG3092" - CG3092 11-Aug-17 DroID_v2017_08 Drer\zgc:123096 Scer\MBA1 Cele\Y62E10A.20 - Mmus\Maip1 Hsap\MAIP1 viable DRSC04336 K 0.453475756 0.110631659 0.056360895 -0.469615307 0.18445314 2.587193803 FBgn0051182 CG31182 - http://flybase.org/reports/FBgn0051182 protein_coding_gene - - - "BcDNA:LD46351, CG31182" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22681 I -0.034657253 -2.40884353 0.256386222 -0.05435962 0.297025618 0.33591759 FBgn0065604 l(2)SH0857 lethal (2) SH0857 http://flybase.org/reports/FBgn0065604 gene - - - l(2)SH0857 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085511 CR40719 - http://flybase.org/reports/FBgn0085511 non_protein_coding_gene - - - "CG40719, CR40719" - CR40719 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024510 dlt discs lost http://flybase.org/reports/FBgn0024510 "FBgn0052315, FBgn0064128" protein_coding_gene - imaginal disc morphogenesis ; GO:0007560 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from expression pattern morphogenesis of a polarized epithelium ; GO:0001738 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "Van, CG32315, l(3)04276, CG1977, l(3)dre1, dre1, l(3)62Ba, dlt, Dlt, DLT" "IPR028171:Codanin-1, C-terminal domain" CG32315 11-Aug-17 DroID_v2017_08 Drer\cdan1 - - Xtro\cdan1 "Mmus\Cdan1, Mmus\Ttbk2" Hsap\CDAN1 " embryonic stage -- adult stage , embryonic stage " epithelial cell

" embryonic stage , embryonic stage | cycle 14 " " ectoderm

, embryonic/larval salivary gland

, embryonic/larval foregut

, embryonic/larval hindgut

, embryonic/larval trachea

, furrow canal

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,cell size defective,decreased cell number,increased cell death,partially lethal - majority live,viable,visible" "leg,eye-antennal disc,follicle cell,somatic clone,imaginal disc,embryonic/larval salivary gland,eye,wing disc,wing,crossvein,wing hair,supernumerary,chaeta,trichogen cell" DRSC08705 E 0.42012238 -1.465377717 -1.67811885 0.124838963 0.047645153 0.143941912 FBgn0033696 Cyp6g2 Cyp6g2 http://flybase.org/reports/FBgn0033696 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 response to insecticide ; GO:0017085 | inferred from mutant phenotype" - "6g2, CG8859, Cyp6g2, Cyp6G2" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV, IPR017972:Cytochrome P450, conserved site" CG8859 11-Aug-17 DroID_v2017_08 "Drer\cyp3c4, Drer\cyp3c3, Drer\cyp3a65, Drer\tbxas1, Drer\cyp3c1, Drer\cyp3c2" Scer\ERG11 "Cele\cyp-25A6, Cele\cyp-25A3, Cele\cyp-13A11, Cele\cyp-13A4, Cele\cyp-13B1, Cele\cyp-25A1, Cele\cyp-13A5, Cele\cyp-13A7, Cele\cyp-13A10, Cele\cyp-13A8, Cele\cyp-25A2, Cele\cyp-13A1, Cele\cyp-44A1, Cele\cyp-13A3, Cele\cyp-43A1, Cele\cyp-13B2, Cele\cyp-25A4, Cele\cyp-13A6, Cele\cyp-13A12, Cele\cyp-13A2" "Xtro\cyp3a4, Xtro\cyp3a5, Xtro\LOC100494419, Xtro\tbxas1" "Mmus\Cyp3a13, Mmus\Cyp3a11, Mmus\Cyp3a57, Mmus\Cyp3a44, Mmus\Cyp3a41b, Mmus\Cyp3a59, Mmus\Cyp3a25, Mmus\Cyp3a16, Mmus\Tbxas1, Mmus\Cyp3a41a" "Hsap\CYP3A5, Hsap\CYP3A4, Hsap\CYP3A7, Hsap\CYP3A7-CYP3A51P, Hsap\TBXAS1, Hsap\CYP3A43" "chemical resistant,viable" FBgn0044122 E(rst)B54 E(rst)B54 http://flybase.org/reports/FBgn0044122 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B54, E(rst)B54" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0264447 CR43865 - http://flybase.org/reports/FBgn0264447 non_protein_coding_gene - - - CR43865 - CR43865 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038475 Keap1 Keap1 http://flybase.org/reports/FBgn0038475 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 protein homodimerization activity ; GO:0042803 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN001229449 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from biological aspect of ancestor with PANTHER:PTN001973695 "CG3962, dKEAP1, Keap1, KEAP1, keap1, dKeap1, dkeap1, Nrf-2, dkeap-1, DmKeap1, Keap-1" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR015915:Kelch-type beta propeller" CG3962 11-Aug-17 DroID_v2017_08 "Drer\klhl29, Drer\LOC100334314, Drer\klhl43, Drer\klhl2, Drer\klhl31, Drer\keap1a, Drer\klhl3, Drer\keap1b, Drer\kbtbd8" - Cele\kel-8 Xtro\keap1 "Mmus\Klhl3, Mmus\Klhl31, Mmus\Keap1, Mmus\Ccin, Mmus\Klhl29, Mmus\Kbtbd8, Mmus\Klhl2" "Hsap\KBTBD8, Hsap\KLHL3, Hsap\KLHL29, Hsap\KLHL2, Hsap\CCIN, Hsap\KEAP1, Hsap\KLHL31" "large body,developmental rate defective,oxidative stress response defective,dominant,male limited,long lived" FBgn0011053 l(1)Q6 lethal (1) Q6 http://flybase.org/reports/FBgn0011053 FBgn0010210 gene - - - l(1)Q6 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053400 5SrRNA:CR33400 5SrRNA:CR33400 http://flybase.org/reports/FBgn0053400 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33400, 5SrRNA:CR33400" - CR33400 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002157 l(2)NS lethal (2) NS http://flybase.org/reports/FBgn0002157 - gene - - - l(2)NS - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" embryonic/larval tracheal system FBgn0002092 l(2)57Bb lethal (2) 57Bb http://flybase.org/reports/FBgn0002092 - gene - - - l(2)57Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266724 Trs20 TRAPP subunit 20 http://flybase.org/reports/FBgn0266724 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatogenesis ; GO:0007283 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000000458 dsRNA transport ; GO:0033227 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000000458 "CG5161, Trs20p, Trs20, l(3)72Dh, E(smoDN)B-left, BcDNA:RE62842, Group B-left" "IPR006722:Trafficking protein particle complex subunit 2, IPR011012:Longin-like domain" CG5161 11-Aug-17 DroID_v2017_08 "Drer\trappc2, Drer\ccdc88c, Drer\ccdc88b, Drer\ccdc88aa" Scer\TRS20 "Cele\sedl-1, Cele\grdn-1" "Xtro\trappc2, Xtro\ccdc88c, Xtro\ccdc88a" "Mmus\Trappc2, Mmus\0610009B22Rik, Mmus\Ccdc88c, Mmus\Ccdc88b, Mmus\Ccdc88a" "Hsap\TRAPPC2, Hsap\CCDC88B, Hsap\CCDC88A, Hsap\CCDC88C" DRSC10489 IE 1.911156749 0.051813665 2.805822283 -0.631207322 0.045684172 0.165581332 FBgn0085588 CG41267 - http://flybase.org/reports/FBgn0085588 protein_coding_gene - - - CG41267 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259308 EP-19 - http://flybase.org/reports/FBgn0259308 gene - - - "EP-19, EP-(19)" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0266686 CR45176 - http://flybase.org/reports/FBgn0266686 non_protein_coding_gene - - - CR45176 - CR45176 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265941 CR44728 - http://flybase.org/reports/FBgn0265941 non_protein_coding_gene - - - "lincRNA.129, CR44728" - CR44728 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001821 l(1)te lethal (1) tracheae enlarged http://flybase.org/reports/FBgn0001821 - gene - - - l(1)te - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval posterior spiracle,embryonic/larval tracheal system" FBgn0038610 CG7675 - http://flybase.org/reports/FBgn0038610 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - cytosol ; GO:0005829 | inferred from direct assay CG7675 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG7675 11-Aug-17 DroID_v2017_08 "Drer\rdh12, Drer\rdh14b, Drer\zgc:64106, Drer\cbr1l, Drer\flj13639, Drer\si:dkey-73n8.3, Drer\rdh14a, Drer\si:dkey-174n20.1, Drer\dhrs13a.3, Drer\dhrs13a.1, Drer\cbr1, Drer\dhrs12, Drer\ascc1, Drer\si:dkey-23o4.6, Drer\zgc:153441, Drer\dhrsx, Drer\si:dkey-94e7.2, Drer\si:ch211-107o10.3, Drer\rdh12l, Drer\dhrs13a.2, Drer\zgc:112332, Drer\si:ch211-165b10.3, Drer\dhrs13l1" "Scer\YKL107W, Scer\YNL181W, Scer\ENV9" Cele\C27D8.4 "Xtro\dhrs13, Xtro\rdh11, Xtro\rdh14, Xtro\dhrsx, Xtro\ascc1, Xtro\dhrs12, Xtro\rdh13" "Mmus\Rdh14, Mmus\1700003E16Rik, Mmus\Ascc1, Mmus\Rdh11, Mmus\Cbr1, Mmus\Rdh12, Mmus\Cbr3, Mmus\Wwox, Mmus\Rdh13, Mmus\Dhrsx, Mmus\Dhrs13" "Hsap\CBR3, Hsap\DHRS13, Hsap\C2orf81, Hsap\DHRSX, Hsap\RDH13, Hsap\RDH11, Hsap\OSTC, Hsap\RDH12, Hsap\CBR1, Hsap\RDH14, Hsap\DHRS12" viable DRSC16280 I 1.887519436 0.177421493 0.329185816 0.034602998 -0.090334185 -0.478717547 FBgn0069333 UY536 UY536 http://flybase.org/reports/FBgn0069333 gene - - - UY536 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell" FBgn0038349 AOX3 Aldehyde oxidase 3 http://flybase.org/reports/FBgn0038349 protein_coding_gene "electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001041 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR006058 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR016166 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR016208 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 xanthine dehydrogenase activity ; GO:0004854 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 aldehyde oxidase activity ; GO:0004031 | inferred from mutant phenotype" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002346, InterPro:IPR002888, InterPro:IPR008274, InterPro:IPR016166, InterPro:IPR016208 acetaldehyde metabolic process ; GO:0006117 | inferred from mutant phenotype xanthine catabolic process ; GO:0009115 | inferred from biological aspect of ancestor with PANTHER:PTN000225632" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 "DmAO3, CG6045, AOX3" "IPR000674:Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR002346:Molybdopterin dehydrogenase, FAD-binding, IPR002888:[2Fe-2S]-binding, IPR005107:CO dehydrogenase flavoprotein, C-terminal, IPR006058:2Fe-2S ferredoxin, iron-sulphur binding site, IPR008274:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding, IPR016166:FAD-binding, type 2, IPR016169:CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR016208:Aldehyde oxidase/xanthine dehydrogenase, IPR016167:FAD-binding, type 2, subdomain 1, IPR012675:Beta-grasp domain" CG6045 11-Aug-17 DroID_v2017_08 "Drer\aox5, Drer\aox6, Drer\xdh" - "Cele\F55B11.1, Cele\F15E6.6, Cele\gad-3" Xtro\xdh "Mmus\Aox4, Mmus\Aox3, Mmus\Aox1, Mmus\Xdh, Mmus\Aox2" "Hsap\AOX1, Hsap\XDH" viable FBgn0013386 anon-100CDa anon-100CDa http://flybase.org/reports/FBgn0013386 - gene - - - "pCY870, pc870, anon-100CDa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265314 CR44287 - http://flybase.org/reports/FBgn0265314 non_protein_coding_gene - - - CR44287 - CR44287 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001575 l(1)1074-ts lethal (1) 1074 ts http://flybase.org/reports/FBgn0001575 - gene - - - "l(1)1074[ts], l(1)1074-ts" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "gastrula embryo,embryonic/larval somatic muscle,embryonic/larval cuticle" FBgn0069169 mcl(3)Z0777 mcl(3)Z0777 http://flybase.org/reports/FBgn0069169 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z0777 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0029015 l(3)77CDj lethal (3) 77CDj http://flybase.org/reports/FBgn0029015 gene - - - l(3)77CDj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,partially lethal - majority die,some die during pharate adult stage" "eye,adult thorax & microchaeta" FBgn0005175 l(2)R lethal of Redfield http://flybase.org/reports/FBgn0005175 - gene - - - l(2)R - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069212 hyp-K hyp-K http://flybase.org/reports/FBgn0069212 gene - - - "hyp[K], hyp-K" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019952 Orct Organic cation transporter http://flybase.org/reports/FBgn0019952 - protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 apoptotic process ; GO:0006915 | traceable author statement integral component of membrane ; GO:0016021 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 "CG6331, Orct, orct" "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG6331 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-119m7.4, Drer\sv2c, Drer\svopa, Drer\zgc:153639, Drer\slc22a15, Drer\si:dkey-166k12.1, Drer\sv2bb, Drer\slc22a2, Drer\slc22a7a, Drer\sv2a, Drer\slc22a16, Drer\slc22a5, Drer\slc22a4, Drer\slc22a6l, Drer\slc22a7b.1, Drer\slc22a21" "Scer\GIT1, Scer\PHO84, Scer\HXT9" "Cele\C06H5.6, Cele\svop-1, Cele\oct-1, Cele\Y82E9BR.16, Cele\B0361.11, Cele\F45E10.2" "Xtro\sv2a, Xtro\slc22a16, Xtro\slc22a6, Xtro\slc22a4, Xtro\slc22a15.2, Xtro\sv2c, Xtro\sv2b, Xtro\slc22a5, Xtro\slc22a13, Xtro\svop" "Mmus\Slc22a13, Mmus\Slc22a6, Mmus\Slc22a21, Mmus\Slc22a5, Mmus\Slc22a16, Mmus\Slc22a7, Mmus\Sv2b, Mmus\Slc22a1, Mmus\Slc22a3, Mmus\Slc22a8, Mmus\Slc22a12, Mmus\Slc22a20, Mmus\Sv2a, Mmus\Sv2c, Mmus\Slc22a4, Mmus\Svop" "Hsap\SLC22A7, Hsap\SLC22A13, Hsap\SLC22A8, Hsap\SLC22A5, Hsap\SVOP, Hsap\SLC22A16, Hsap\SLC22A12, Hsap\SV2B, Hsap\SLC22A3, Hsap\SV2A, Hsap\SLC22A4, Hsap\SV2C, Hsap\SLC22A20, Hsap\SLC22A6" embryonic stage && larval stage && adult stage viable FBgn0027178 l(2)60Af lethal (2) 60Af http://flybase.org/reports/FBgn0027178 - gene - - - l(2)60Af - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029836 CG5928 - http://flybase.org/reports/FBgn0029836 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5928 - CG5928 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0031483 CG9641 - http://flybase.org/reports/FBgn0031483 protein_coding_gene - - - CG9641 IPR031961:Domain of unknown function DUF4780 CG9641 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039155 Kal1 Kallmann syndrome 1 http://flybase.org/reports/FBgn0039155 protein_coding_gene peptidase inhibitor activity ; GO:0030414 | inferred from electronic annotation with InterPro:IPR008197 - proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity external side of plasma membrane ; GO:0009897 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay "CG6173, Dmkal, CT19368, DmKal-1, Kal1, kal-1, Kal-1" "IPR003961:Fibronectin type III, IPR008197:WAP-type 'four-disulfide core' domain, IPR013783:Immunoglobulin-like fold" CG6173 11-Aug-17 DroID_v2017_08 "Drer\LOC100535716, Drer\anos1b, Drer\anos1a" - Cele\kal-1 Xtro\anos1 "Mmus\Wfdc18, Mmus\Wfdc17" "Hsap\WFDC2, Hsap\ANOS1" "partially lethal - majority die,size defective,viable,fertile" "mouth hooks,median tooth,lateral process,hypostomal sclerite,wing vein L4,submarginal cell,wing vein L2,wing vein L3,wing margin,wing,cephalopharyngeal skeleton" FBgn0065405 l(2)SH1586 lethal (2) SH1586 http://flybase.org/reports/FBgn0065405 gene - - - "l(2)SH1586, l(2)SH2 1586" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032000 CG8372 - http://flybase.org/reports/FBgn0032000 protein_coding_gene - - - CG8372 IPR008496:Protein of unknown function DUF778 CG8372 11-Aug-17 DroID_v2017_08 "Drer\tmem222b, Drer\tmem222a" - Cele\H20J04.6 Xtro\tmem222 Mmus\Tmem222 Hsap\TMEM222 viable FBgn0267474 CR45824 - http://flybase.org/reports/FBgn0267474 non_protein_coding_gene - - - CR45824 - CR45824 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024243 dsx::fru dsx::fru http://flybase.org/reports/FBgn0024243 - engineered_fusion_gene - - - dsx::fru - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033750 CG13151 - http://flybase.org/reports/FBgn0033750 protein_coding_gene - - - CG13151 "IPR032718:PiggyBac transposable element-derived protein 4, C-terminal zinc-ribbon, IPR029526:PiggyBac transposable element-derived protein" CG13151 11-Aug-17 DroID_v2017_08 Drer\dusp26 - - - - - viable FBgn0060874 l(3)S045831 lethal (3) S045831 http://flybase.org/reports/FBgn0060874 gene - - - "0458/31, l(3)S045831" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061476 Zwilch Zwilch http://flybase.org/reports/FBgn0061476 protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with rod, Zw10" mitotic cell cycle checkpoint ; GO:0007093 | inferred from sequence or structural similarity with UniProtKB:Q9H900 mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype "cytoplasm ; GO:0005737 | inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay RZZ complex ; GO:1990423 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay RZZ complex ; GO:1990423 | inferred from physical interaction with rod, Zw10" "CG18729, CG18639, zwilch, Zwilch" "IPR018630:RZZ complex, subunit zwilch" CG18729 11-Aug-17 DroID_v2017_08 Drer\zwilch - Cele\zwl-1 Xtro\zwilch Mmus\Zwilch Hsap\ZWILCH "viable,fertile,female sterile,recessive,mitotic cell cycle defective,meiotic cell cycle defective" anaphase & condensed nuclear chromosome FBgn0060944 l(3)S038307 lethal (3) S038307 http://flybase.org/reports/FBgn0060944 gene - - - "0383/07, l(3)S038307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0264540 CG43919 - http://flybase.org/reports/FBgn0264540 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43919 - CG43919 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040569 CR14310 - http://flybase.org/reports/FBgn0040569 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "R5_3R:14198558..14199807, CG14310, CR14310" - CR14310 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027052 STUB1 STIP1 homology and U-box containing protein 1 http://flybase.org/reports/FBgn0027052 - protein_coding_gene Hsp90 protein binding ; GO:0051879 | inferred from sequence or structural similarity with UniProtKB:Q9UNE7 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay protein dimerization activity ; GO:0046983 | inferred from physical interaction with STUB1 protein ubiquitination ; GO:0016567 | inferred from direct assay Z disc ; GO:0030018 | colocalizes_with inferred from direct assay "dCHIP, CG5203, Chip, CHIP, STUB1" "IPR003613:U box domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5203 11-Aug-17 DroID_v2017_08 Drer\stub1 Scer\TAH1 Cele\chn-1 Xtro\stub1 Mmus\Stub1 Hsap\STUB1 viable DRSC03282 E 0.26167502 -0.936237011 0.103770339 1.585978191 0.410385317 -1.388925335 FBgn0060752 l(3)S064411a lethal (3) S064411a http://flybase.org/reports/FBgn0060752 gene - - - "1103/05, 1103/03, 0644/11, l(3)S110303, l(3)S110305a, l(3)S064411a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262256 mir-959 mir-959 stem loop http://flybase.org/reports/FBgn0262256 miRNA_gene - "regulation of feeding behavior ; GO:0060259 | inferred from genetic interaction with mir-960, mir-961, mir-962 immune response ; GO:0006955 | inferred from genetic interaction with mir-960, mir-961, mir-962" - "dme-mir-959, miR-959, mir-959, CR42963, dme-miR-959-3p" - CR42963 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005324 Nu Nude on 2 or 3 http://flybase.org/reports/FBgn0005324 - gene - - - Nu - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "adult head & macrochaeta,adult thorax & macrochaeta" FBgn0060703 l(3)S071502 lethal (3) S071502 http://flybase.org/reports/FBgn0060703 gene - - - "0715/02, l(3)S071502" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046296 CG11534 - http://flybase.org/reports/FBgn0046296 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 cellular_component ; GO:0005575 | no biological data available "BEST:GH12489, CG11534" "IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR025258:Putative zinc-RING and/or ribbon, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11534 11-Aug-17 DroID_v2017_08 Drer\def8 - "Cele\F20H11.1, Cele\Y56A3A.16" Xtro\def8 Mmus\Def8 Hsap\DEF8 viable DRSC09840 EK -0.341392414 -0.524061291 -1.546208576 0.11727658 -1.026181247 -1.536066311 FBgn0267752 CR46083 - http://flybase.org/reports/FBgn0267752 non_protein_coding_gene - - - CR46083 - CR46083 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000021 abw abnormal wings http://flybase.org/reports/FBgn0000021 - gene - - - abw - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "wing,wing vein,wing vein L5" FBgn0000952 Fs(2)D10 Female sterile D10 http://flybase.org/reports/FBgn0000952 - gene - - - Fs(2)D10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,dominant" embryo FBgn0065669 l(2)SH0688 lethal (2) SH0688 http://flybase.org/reports/FBgn0065669 gene - - - "l(2)SH0688, l(2)SH2 0688" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263593 Lpin Lipin http://flybase.org/reports/FBgn0263593 protein_coding_gene phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000256564 transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity with MGI:MGI:1891340 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000256565 phosphatidate phosphatase activity ; GO:0008195 | inferred from sequence or structural similarity with MGI:MGI:1891340 lipid homeostasis ; GO:0055088 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype triglyceride biosynthetic process ; GO:0019432 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:1891340 regulation of fatty acid metabolic process ; GO:0019217 | inferred from mutant phenotype negative regulation of BMP signaling pathway ; GO:0030514 | inferred from mutant phenotype inferred from genetic interaction with Dad imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype regulation of cellular ketone metabolic process ; GO:0010565 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000256565 fatty acid catabolic process ; GO:0009062 | inferred from biological aspect of ancestor with PANTHER:PTN000256565 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay female germline ring canal inner rim ; GO:0035183 | inferred from direct assay "CG8709, DmLpin, anon-WO0118547.133, Lpin, EP2431, LIPIN, DLpin, dLipin" "IPR023214:HAD-like domain, IPR007651:Lipin, N-terminal, IPR013209:Lipin/Ned1/Smp2 (LNS2), IPR031315:LNS2/PITP, IPR031703:Lipin, middle domain" CG8709 11-Aug-17 DroID_v2017_08 "Drer\lpin1, Drer\zgc:123305, Drer\lipin2, Drer\si:ch73-21k16.1" Scer\PAH1 Cele\lpin-1 "Xtro\lpin2, Xtro\lpin1, Xtro\lpin3" "Mmus\Lpin2, Mmus\Lpin3, Mmus\Lpin1" "Hsap\LPIN3, Hsap\LPIN2, Hsap\LPIN1" FBgn0031257 CG4133 - http://flybase.org/reports/FBgn0031257 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG4133 "IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG4133 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023047 l(1)3Ap lethal (1) 3Ap http://flybase.org/reports/FBgn0023047 - gene - - - "1200D2b, l(1)3Ap" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005619 Hdc Histidine decarboxylase http://flybase.org/reports/FBgn0005619 FBgn0044609 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 histidine decarboxylase activity ; GO:0004398 | inferred from sequence or structural similarity inferred from mutant phenotype cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010977 phototransduction ; GO:0007602 | inferred from mutant phenotype thermotaxis ; GO:0043052 | inferred from mutant phenotype - "Hdc, hdc, JK910, CG3454, anon-WO0140519.259" "IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR010977:Aromatic-L-amino-acid decarboxylase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase, IPR021115:Pyridoxal-phosphate binding site" CG3454 11-Aug-17 DroID_v2017_08 "Drer\ddc, Drer\hdc" - "Cele\hdl-2, Cele\hdl-1" "Xtro\hdc, Xtro\ddc" "Mmus\Ddc, Mmus\Hdc" "Hsap\DDC, Hsap\HDC" adult stage " adult brain cortex

, photoreceptor cell

, retina

, thoracico-abdominal ganglion

" "wild-type,visual behavior defective,recessive,neurophysiology defective,grooming behavior defective,behavior defective,viable,thermotaxis behavior defective,paralytic,heat sensitive" "retina,lobula plate,synaptic vesicle,photoreceptor cell" FBgn0067352 l(3)95EFd lethal (3) 95EFd http://flybase.org/reports/FBgn0067352 gene - - - l(3)95EFd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" embryo FBgn0262787 CG43168 - http://flybase.org/reports/FBgn0262787 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43168, chr3L_6268776_6270114.0, lincRNA.451" - CG43168 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040636 CG13255 - http://flybase.org/reports/FBgn0040636 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13255 - CG13255 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0086403 BG02601 - http://flybase.org/reports/FBgn0086403 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02601 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0030989 Inx5 Innexin 5 http://flybase.org/reports/FBgn0030989 protein_coding_gene gap junction channel activity ; GO:0005243 | inferred from sequence or structural similarity with Inx3 intercellular transport ; GO:0010496 | inferred from sequence or structural similarity with Inx3 integral component of membrane ; GO:0016021 | non-traceable author statement gap junction ; GO:0005921 | inferred from direct assay "inx-5, Dm-inx5, CG7537, FBpp0074467, inx5, Inx5" IPR000990:Innexin CG7537 11-Aug-17 DroID_v2017_08 "Drer\panx3, Drer\panx1b" - "Cele\inx-20, Cele\inx-16, Cele\che-7, Cele\inx-15, Cele\inx-9, Cele\inx-10, Cele\inx-19, Cele\inx-21, Cele\inx-6, Cele\inx-7, Cele\inx-11, Cele\unc-7, Cele\inx-5, Cele\inx-3, Cele\inx-17, Cele\inx-2, Cele\unc-9, Cele\eat-5, Cele\inx-18, Cele\inx-22, Cele\inx-12, Cele\inx-13, Cele\inx-8, Cele\inx-1, Cele\inx-14" - - - viable FBgn0032700 CG10338 - http://flybase.org/reports/FBgn0032700 protein_coding_gene - - - CG10338 IPR006968:Root UVB sensitive family CG10338 11-Aug-17 DroID_v2017_08 Drer\zgc:162613 - "Cele\srd-44, Cele\srd-42, Cele\srd-43" Xtro\c16orf58 Mmus\BC017158 Hsap\C16orf58 viable FBgn0053383 5SrRNA:CR33383 5SrRNA:CR33383 http://flybase.org/reports/FBgn0053383 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33383, 5SrRNA:CR33383" - CR33383 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043002 Chrac-14 Chromatin accessibility complex 14kD protein http://flybase.org/reports/FBgn0043002 protein_coding_gene nucleosome-dependent ATPase activity ; GO:0070615 | contributes_to inferred by curator from GO:0008623 protein binding ; GO:0005515 | inferred from physical interaction with Iswi protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Chrac-16 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype nucleosome mobilization ; GO:0042766 | inferred from direct assay cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay CENP-A containing nucleosome assembly ; GO:0034080 | inferred from mutant phenotype inferred from genetic interaction with HipHop CHRAC ; GO:0008623 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from physical interaction with Ada2a "CHRAC14, CHRAC, CHRAC-14, mary, 55A11T, CG32956, ESTS:55A11T, CG13399, Chrac-14, 13399, 18K protein, Chrac14, chrac-14" "IPR003958:Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072:Histone-fold" CG13399 11-Aug-17 DroID_v2017_08 "Drer\nfyba, Drer\pole3" "Scer\DPB4, Scer\HAP3" "Cele\nfyb-1, Cele\T26A5.8" "Xtro\nfyb, Xtro\pole3" "Mmus\Nfyb, Mmus\Pole3" Hsap\POLE3 "mitotic cell cycle defective,viable,fertile,eclosion defective,radiation sensitive,DNA repair defective,tumorigenic,flight defective" "chromosomearm.PS,wing" FBgn0052569 TwdlZ TweedleZ http://flybase.org/reports/FBgn0052569 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlZ, CG32569" IPR004145:Domain of unknown function DUF243 CG32569 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002710 mei-251 meiotic 251 http://flybase.org/reports/FBgn0002710 - gene - reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - mei-251 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" FBgn0014900 anon-10Ag anon-10Ag http://flybase.org/reports/FBgn0014900 - gene - - - anon-10Ag - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084026 CG41465 - http://flybase.org/reports/FBgn0084026 protein_coding_gene - - - CG41465 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259644 B1034 - http://flybase.org/reports/FBgn0259644 gene - - - B1034 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0259996 CR40341 - http://flybase.org/reports/FBgn0259996 non_protein_coding_gene - - - "CG40341, CR40341, anon-38C.21, 38C.21" - CR40341 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004152 l(2)57Af lethal (2) 57Af http://flybase.org/reports/FBgn0004152 - gene - - - l(2)57Af - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266110 mei-889 meiotic 889 http://flybase.org/reports/FBgn0266110 gene - female meiotic division ; GO:0007143 | inferred from mutant phenotype - mei-889 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,meiotic cell cycle defective,female" FBgn0266411 sima similar http://flybase.org/reports/FBgn0266411 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000548738" "regulation of cell cycle ; GO:0051726 | inferred from direct assay regulation of cell migration ; GO:0030334 | inferred from mutant phenotype regulation of innate immune response ; GO:0045088 | inferred from mutant phenotype cellular response to insulin stimulus ; GO:0032869 | inferred from direct assay cellular response to hypoxia ; GO:0071456 | inferred from direct assay positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype trachea development ; GO:0060438 | inferred from mutant phenotype inferred from genetic interaction with Vhl positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from sequence or structural similarity with HGNC:4910 oogenesis ; GO:0048477 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with HGNC:4910 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "sima, HIF1alpha, CG45051, CG7951, HIF-1alpha, Sima, Hif-1A, SIMA, DMU43090, l(3)j11B7, HIF-1, HIF alpha, HIF-alpha/sima, bHLHe56, 7951, dHIF-alpha, dHIF-1alpha, Hif1alpha, CG31031, HIF1A, HIFalpha" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR000014:PAS domain, IPR001610:PAC motif, IPR013655:PAS fold-3, IPR013767:PAS fold, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG45051 11-Aug-17 DroID_v2017_08 "Drer\hif1ab, Drer\hif1al2, Drer\hif1aa, Drer\hif1al, Drer\epas1a, Drer\npas1, Drer\epas1b" - Cele\hif-1 "Xtro\npas3, Xtro\hif1a, Xtro\epas1" "Mmus\Hif3a, Mmus\Hif1a, Mmus\Npas1, Mmus\Npas3, Mmus\Epas1" "Hsap\HIF3A, Hsap\AHR, Hsap\EPAS1, Hsap\NPAS1, Hsap\HIF1A, Hsap\NPAS3" embryonic stage

ubiquitous FBgn0262890 CG43245 - http://flybase.org/reports/FBgn0262890 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43245 - CG43245 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054043 CG34043 - http://flybase.org/reports/FBgn0054043 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000669108 "BP1017, CG34043" "IPR009003:Peptidase S1, PA clan" CG34043 11-Aug-17 DroID_v2017_08 "Drer\zgc:163025, Drer\proza, Drer\prozb, Drer\proca" - - - "Mmus\Proc, Mmus\Proz" "Hsap\PROC, Hsap\PROZ" FBgn0062599 Mod(var)1474 Mod(var)1474 http://flybase.org/reports/FBgn0062599 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1474, Mod(var)1474" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0040843 CG15213 - http://flybase.org/reports/FBgn0040843 protein_coding_gene - - - CG15213 - CG15213 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051133 Slimp Seryl-tRNA synthetase-like insect mitochondrial protein http://flybase.org/reports/FBgn0051133 protein_coding_gene serine-tRNA ligase activity ; GO:0004828 | NOT inferred from direct assay tRNA binding ; GO:0000049 | inferred from direct assay ATP binding ; GO:0005524 | NOT inferred from direct assay mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype seryl-tRNA aminoacylation ; GO:0006434 | NOT inferred from direct assay cellular respiration ; GO:0045333 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "BcDNA:LD24627, CG31133, Slimp, SLIMP" "IPR002317:Serine-tRNA ligase, type1, IPR010978:tRNA-binding arm, IPR015866:Serine-tRNA synthetase, type1, N-terminal" CG31133 11-Aug-17 DroID_v2017_08 "Drer\sars, Drer\sars2" "Scer\DIA4, Scer\SES1" Cele\sars-2 "Xtro\sars2, Xtro\sars" "Mmus\Sars, Mmus\Sars2" "Hsap\TARS, Hsap\SARS, Hsap\FBXO17, Hsap\SARS2" "decreased cell number,lethal,heat sensitive,viable" "wing cell,cell autonomous,anterior crossvein,mitochondrion" FBgn0030009 CG15336 - http://flybase.org/reports/FBgn0030009 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG15336 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG15336 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-7l6.3, Drer\zgc:66443, Drer\si:ch211-113e8.10, Drer\si:ch73-138e16.4" "Scer\STP4, Scer\ZAP1, Scer\STP3" "Cele\snai-1, Cele\F56D1.1" - "Mmus\Zfp91, Mmus\Zfp275" "Hsap\ZNF235, Hsap\ZNF407, Hsap\ZFP91, Hsap\ZNF275" viable FBgn0039993 CG17691 - http://flybase.org/reports/FBgn0039993 protein_coding_gene 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity ; GO:0003863 | inferred from sequence or structural similarity with UniProtKB:P21953 fatty-acyl-CoA biosynthetic process ; GO:0046949 | inferred from sequence or structural similarity with UniProtKB:P12694 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex ; GO:0017086 | inferred from sequence or structural similarity with UniProtKB:P21953 CG17691 "IPR005475:Transketolase-like, pyrimidine-binding domain, IPR009014:Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II, IPR029061:Thiamin diphosphate-binding fold, IPR033248:Transketolase, C-terminal domain" CG17691 11-Aug-17 DroID_v2017_08 Drer\bckdhb Scer\PDB1 Cele\tag-173 Xtro\bckdhb Mmus\Bckdhb Hsap\BCKDHB viable FBgn0028648 mRpL50 mitochondrial ribosomal protein L50 http://flybase.org/reports/FBgn0028648 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement mitochondrion ; GO:0005739 | inferred from electronic annotation with InterPro:IPR018305 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "MRP-L50, ANON-65Eb, anon-65Eb, CG8612, BcDNA:GM06185, BcDNA:RE06140, mRpL50" "IPR018305:Ribosomal protein L50, mitochondria" CG8612 11-Aug-17 DroID_v2017_08 - - Cele\mrpl-50 - Mmus\Mrpl50 Hsap\MRPL50 "developmental rate defective,RU486 conditional,short lived,male,female,viable,visible" trichogen cell DRSC11015 K -0.83537068 -1.122024227 0.692639258 0.045240785 -1.580903454 -0.288927931 FBgn0033274 CG14757 - http://flybase.org/reports/FBgn0033274 protein_coding_gene copper ion binding ; GO:0005507 | inferred from sequence model "mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from biological aspect of ancestor with PANTHER:PTN000279729 mitochondrial respiratory chain complex II assembly ; GO:0034553 | inferred from biological aspect of ancestor with PANTHER:PTN000279729 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN002287625 protein-FAD linkage ; GO:0018293 | inferred from biological aspect of ancestor with PANTHER:PTN002287625 copper ion homeostasis ; GO:0055070 | inferred from expression pattern mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from sequence or structural similarity with UniProtKB:Q9NX18 protein-FAD linkage ; GO:0018293 | inferred from sequence or structural similarity with UniProtKB:Q9NX18" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9NX18 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000279729 "146793_at, CG14757" "IPR005631:Flavinator of succinate dehydrogenase, IPR028882:Succinate dehydrogenase assembly factor 2, mitochondrial" CG14757 11-Aug-17 DroID_v2017_08 Drer\sdhaf2 Scer\SDH5 Cele\Y57A10A.29 Xtro\sdhaf2 Mmus\Sdhaf2 Hsap\SDHAF2 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0053363 5SrRNA-Psi:CR33363 5SrRNA-Psi:CR33363 http://flybase.org/reports/FBgn0053363 pseudogene_attribute - - - "CR33363, 5SrRNA-Psi:CR33363" - CR33363 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041133 l(2)44Fi lethal (2) 44Fi http://flybase.org/reports/FBgn0041133 gene - - - l(2)44Fi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0259840 Su(Ste):CR42409 Su(Ste):CR42409 http://flybase.org/reports/FBgn0259840 non_protein_coding_gene - - - "Su(Ste):CR42409, CR42409" - CR42409 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262443 mir-286 mir-286 stem loop http://flybase.org/reports/FBgn0262443 miRNA_gene - - - "mir-286, 286, miR-286, CR43006, Mir-286, CR33602, dme-miR-286" - CR43006 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0050163 Cpr60D Cuticular protein 60D http://flybase.org/reports/FBgn0050163 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG4856, BcDNA:RH24125, Cpr60D, CG30163, cpr60d" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG30163 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0001990 wek weckle http://flybase.org/reports/FBgn0001990 "FBgn0027899, FBgn0032571" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein binding ; GO:0005515 | inferred from physical interaction with Myd88 inferred from physical interaction with Tl protein homodimerization activity ; GO:0042803 | inferred from direct assay "maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype activation of innate immune response ; GO:0002218 | NOT inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "l(2)35Ea, CG4148, BG:DS09217.5, l35Ea, l(2)br47, wek" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG4148 11-Aug-17 DroID_v2017_08 "Drer\zgc:193790, Drer\zfx, Drer\LOC101885937" Scer\AZF1 "Cele\let-391, Cele\F58G1.2, Cele\F26A10.2, Cele\blmp-1, Cele\klu-1" - - - "visible,recessive,viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "leg,wing,embryonic ventral epidermis,germline clone,non-rescuable maternal effect,embryonic/first instar larval cuticle,ventral,filzkorper" FBgn0010920 l(3)07217 lethal (3) 07217 http://flybase.org/reports/FBgn0010920 - gene - - - "l(3)02067, l(3)07217" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0031379 CG7289 - http://flybase.org/reports/FBgn0031379 protein_coding_gene - - - CG7289 IPR018795:Protein of unknown function DUF2152 CG7289 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-104h9.5 - Cele\C17H12.2 Xtro\kiaa2013 Mmus\2510039O18Rik "Hsap\KIAA2013, Hsap\LOC102724984" viable FBgn0005369 vli veins longitudinally shortened http://flybase.org/reports/FBgn0005369 - gene - - - vli - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semidominant" "wing vein L2,wing vein L4,wing vein L5" FBgn0015338 CG5861 - http://flybase.org/reports/FBgn0015338 FBgn0020603 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000305488 "anon-35Fa, BG:DS02740.11, III, anon-35Fc, CG5861" "IPR019164:Protein of unknown function DUF2053, membrane" CG5861 11-Aug-17 DroID_v2017_08 Drer\tmem147 - Cele\ZK418.5 Xtro\tmem147 Mmus\Tmem147 Hsap\TMEM147 " adult stage , embryonic stage " viable FBgn0033287 CG8701 - http://flybase.org/reports/FBgn0033287 protein_coding_gene - - - "anon-WO0140519.78, CG8701" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG8701 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264745 CR44003 - http://flybase.org/reports/FBgn0264745 pseudogene_attribute - - - "CG44003, CR44003, CG34406-1, CG3485, CG34406" - CR44003 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050419 CG30419 - http://flybase.org/reports/FBgn0050419 protein_coding_gene - - - "CG13573, CG13572, CG30419" - CG30419 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0037743 CG8412 - http://flybase.org/reports/FBgn0037743 protein_coding_gene "alpha-1,6-mannosyltransferase activity ; GO:0000009 | inferred from sequence or structural similarity with UniProtKB:P53730 mannosyltransferase activity ; GO:0000030 | inferred from biological aspect of ancestor with PANTHER:PTN000509188" protein glycosylation ; GO:0006486 | inferred from sequence or structural similarity with UniProtKB:P53730 protein N-linked glycosylation ; GO:0006487 | inferred from biological aspect of ancestor with PANTHER:PTN000509189 dolichol-linked oligosaccharide biosynthetic process ; GO:0006488 | inferred from sequence or structural similarity with UniProtKB:P53730 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000509188 "CG8412, dAlg12" IPR005599:GPI mannosyltransferase CG8412 11-Aug-17 DroID_v2017_08 Drer\alg12 Scer\ALG12 Cele\ZC513.5 Xtro\alg12 Mmus\Alg12 Hsap\ALG12 viable FBgn0267613 CR45951 - http://flybase.org/reports/FBgn0267613 non_protein_coding_gene - - - CR45951 - CR45951 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266789 CR45254 - http://flybase.org/reports/FBgn0266789 non_protein_coding_gene - - - CR45254 - CR45254 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020540 l(2)k01015 lethal (2) k01015 http://flybase.org/reports/FBgn0020540 - gene - - - "l(2)01015, l(2)k01015" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264984 CR44135 - http://flybase.org/reports/FBgn0264984 non_protein_coding_gene - - - "CR44135, lincRNA.753" - CR44135 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082585 sprt sprite http://flybase.org/reports/FBgn0082585 protein_coding_gene - - - "CG9026, CG30023, sprt" "IPR001478:PDZ domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG30023 11-Aug-17 DroID_v2017_08 "Drer\pard3ba, Drer\LOC101882925, Drer\pard3bb, Drer\pard3" - Cele\par-3 - "Mmus\Pard3, Mmus\Pard3b" "Hsap\PARD3, Hsap\PARD3B" "viable,fertile" heart primordium FBgn0060883 l(3)S044828 lethal (3) S044828 http://flybase.org/reports/FBgn0060883 gene - - - "0448/28, l(3)S044828" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0263446 CR43469 - http://flybase.org/reports/FBgn0263446 non_protein_coding_gene - - - CR43469 - CR43469 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262453 mir-275 mir-275 stem loop http://flybase.org/reports/FBgn0262453 miRNA_gene - - - "mir-275, miR-275, dme-mir-275, 275, MIR-275, CR43020, CR33583, mir275, dme-miR-275, miR275" - CR43020 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "eye,wing,wing vein,spermatocyte cyst" FBgn0035235 CG7879 - http://flybase.org/reports/FBgn0035235 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0000381 "cg7879, CG7879" IPR000504:RNA recognition motif domain CG7879 11-Aug-17 DroID_v2017_08 "Drer\zgc:153215, Drer\rbm12b, Drer\rbm12" - "Cele\hrpf-2, Cele\Y106G6D.7" "Xtro\rbm12b, Xtro\rbm12, Xtro\rbm12b" "Mmus\Rbm12b1, Mmus\Rbm12b2, Mmus\Rbm12" "Hsap\RBM12B, Hsap\RBM12" "viable,fertile" FBgn0267538 CR45878 - http://flybase.org/reports/FBgn0267538 non_protein_coding_gene - - - CR45878 - CR45878 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031228 ND-15 NADH dehydrogenase (ubiquinone) 15 kDa subunit http://flybase.org/reports/FBgn0031228 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O43920 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O43920" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O43920 "CG11455, NIPM, ND-15" "IPR019342:NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5" CG11455 11-Aug-17 DroID_v2017_08 Drer\ndufs5 - Cele\nduf-5 Xtro\ndufs5 Mmus\Ndufs5 Hsap\NDUFS5 "viable,visible,flight defective,lethal,heat sensitive" trichogen cell FBgn0036996 mag magro http://flybase.org/reports/FBgn0036996 protein_coding_gene sterol esterase activity ; GO:0004771 | inferred from direct assay lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 cholesterol homeostasis ; GO:0042632 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype cytoplasmic vesicle ; GO:0031410 | inferred from direct assay "mag, CG5932, lipA, Mag" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG5932 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\TGL1, Scer\YEH2, Scer\YEH1" "Cele\lipl-2, Cele\lipl-6, Cele\lipl-4, Cele\lipl-1, Cele\lipl-5, Cele\lipl-8, Cele\lipl-7, Cele\lipl-3" Xtro\lipa "Mmus\Lipo1, Mmus\Lipm, Mmus\Lipk, Mmus\Lipn, Mmus\Lipo4, Mmus\Lipf, Mmus\Lipo3, Mmus\Lipa, Mmus\Lipo2" "Hsap\LIPN, Hsap\LIPJ, Hsap\LIPA, Hsap\LIPF, Hsap\LIPM, Hsap\LIPK" FBgn0036832 CG18223 - http://flybase.org/reports/FBgn0036832 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SPH200, BcDNA:AT03311, CG18223" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG18223 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.12, Drer\si:ch211-165b19.8" - "Cele\try-1, Cele\svh-1" Xtro\tpsab1 "Mmus\Gzmg, Mmus\Gzmn, Mmus\Gzmd, Mmus\Gzme, Mmus\Gzmf" "Hsap\AZU1, Hsap\GZMM, Hsap\PRSS55, Hsap\KLK10, Hsap\GZMB, Hsap\GZMH" viable FBgn0003435 sm smooth http://flybase.org/reports/FBgn0003435 "FBgn0010597, FBgn0063694" protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR006536 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR006536 axon guidance ; GO:0007411 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype adult feeding behavior ; GO:0008343 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay "CG9218, l(2)05338, smo, BcDNA:GH10856, sm" "IPR000504:RNA recognition motif domain, IPR006536:HnRNP-L/PTB" CG9218 11-Aug-17 DroID_v2017_08 "Drer\hnrpl, Drer\hnrnpl2" "Scer\MUD1, Scer\MRD1" "Cele\C44B7.2, Cele\rnp-2, Cele\pab-2" Xtro\hnrnpl "Mmus\Hnrnpll, Mmus\Hnrnpl" "Hsap\PABPC4, Hsap\PABPC3, Hsap\PABPC1, Hsap\HNRNPLL, Hsap\HNRNPL" "viable,fertile,partially lethal - majority die,lethal,recessive,visible,feeding behavior defective,neuroanatomy defective,short lived,female sterile,male sterile,long lived,some die during pupal stage" "macrochaeta,dorsal,scutellar bristle,microchaeta,abdominal sternite bristle,chemosensory neuron & tibia,macrochaeta & adult abdomen | ventral,acrostichal bristle,trichogen cell" FBgn0050289 CG30289 - http://flybase.org/reports/FBgn0050289 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG30289 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG30289 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\plat, Drer\habp2, Drer\f7i, Drer\tmprss4a" - "Cele\try-3, Cele\svh-1, Cele\try-1" - "Mmus\Plat, Mmus\Tmprss4, Mmus\Klk1b9, Mmus\Klk1b5, Mmus\Gzmk, Mmus\Prss54, Mmus\Klk1b4, Mmus\Egfbp2, Mmus\Habp2" "Hsap\KLK14, Hsap\PLAT, Hsap\TMPRSS4, Hsap\HABP2, Hsap\GZMK" "partially lethal - majority die,some die during pupal stage" FBgn0060379 l(3)S135111b lethal (3) S135111b http://flybase.org/reports/FBgn0060379 gene - - - "1351/11, l(3)S135111b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0020820 l(3)98Dj lethal (3) 98Dj http://flybase.org/reports/FBgn0020820 - gene - - - "M316, l(3)98Dj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0063492 GstE8 Glutathione S transferase E8 http://flybase.org/reports/FBgn0063492 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from sequence or structural similarity with GstE1 glutathione metabolic process ; GO:0006749 | inferred from sequence or structural similarity with GstE1 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTE8, CG17533, GST3-2, Gst3-2, BcDNA:GM08326, GstE8, GSTE8, gste8" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17533 11-Aug-17 DroID_v2017_08 "Drer\eef1g, Drer\gstt1a, Drer\gstr, Drer\eef1e1, Drer\vars, Drer\gstt2, Drer\mars, Drer\gstt1b" "Scer\TEF4, Scer\GTT2, Scer\URE2, Scer\CAM1, Scer\GTT1, Scer\YGR201C" "Cele\gst-29, Cele\gst-21" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Gstt1, Mmus\Gstt3, Mmus\Eef1g, Mmus\Gstt2, Mmus\Mars, Mmus\Gstt4, Mmus\Eef1e1, Mmus\Vars" "Hsap\MARS, Hsap\VARS, Hsap\EEF1E1, Hsap\GSTT2, Hsap\GSTT2B, Hsap\EEF1G, Hsap\GSTT1" viable FBgn0032868 CG17472 - http://flybase.org/reports/FBgn0032868 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "38D.23, BcDNA:GH20534, CG17472" - CG17472 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085758 CR40639 - http://flybase.org/reports/FBgn0085758 rRNA_gene - - - CR40639 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016049 noy no eye http://flybase.org/reports/FBgn0016049 - gene - - - noy - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065726 l(2)SH0561 lethal (2) SH0561 http://flybase.org/reports/FBgn0065726 gene - - - "l(2)SH0561, l(2)SH2 0561" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265607 beat-IIIa beat-IIIa http://flybase.org/reports/FBgn0265607 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic - "beat-IIIa, beat IIIa, CG12621, CG42757, Beat-IIIa" "IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain" CG12621 11-Aug-17 DroID_v2017_08 Drer\zgc:172106 - - Xtro\f11r - Hsap\CADM2 FBgn0065689 l(2)SH0646 lethal (2) SH0646 http://flybase.org/reports/FBgn0065689 gene - - - "l(2)SH0646, l(2)SH2 0646" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001759 l(1)M9 lethal (1) M9 http://flybase.org/reports/FBgn0001759 - gene - - - l(1)M9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0267536 CR45876 - http://flybase.org/reports/FBgn0267536 non_protein_coding_gene - - - CR45876 - CR45876 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069209 krk krake http://flybase.org/reports/FBgn0069209 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available krk - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic thorax,germline clone,maternal effect,embryo,posterior" FBgn0025766 l(3)89Dd lethal (3) 89Dd http://flybase.org/reports/FBgn0025766 - gene - - - "l(3)M175, l(3)89Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052806 CG32806 - http://flybase.org/reports/FBgn0052806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs06b11, CG32806" - CG32806 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261520 CG32716 - http://flybase.org/reports/FBgn0261520 protein_coding_gene - - - "CG15339, CG32716" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035538 DopEcR Dopamine/Ecdysteroid receptor http://flybase.org/reports/FBgn0035538 protein_coding_gene "ecdysone binding ; GO:0035100 | inferred from direct assay dopamine neurotransmitter receptor activity, coupled via Gs ; GO:0001588 | inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity" positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010579 | inferred from direct assay response to sucrose ; GO:0009744 | inferred from mutant phenotype cellular response to sucrose stimulus ; GO:0071329 | inferred from direct assay habituation ; GO:0046959 | inferred from mutant phenotype positive regulation of MAPK cascade ; GO:0043410 | inferred from direct assay response to ethanol ; GO:0045471 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from mutant phenotype response to ecdysone ; GO:0035075 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity response to starvation ; GO:0042594 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG18314, anon-WO0170980.140, anon-WO0170980.139, DopEcR, DmDopEcR, dop, DopECR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG18314 11-Aug-17 DroID_v2017_08 "Drer\zgc:162592, Drer\gpr52" - "Cele\srx-58, Cele\F59D12.1" "Xtro\cbwd1.1, Xtro\gpr52" "Mmus\Gpr21, Mmus\Gpr52" "Hsap\GPR21, Hsap\GPR52" "neurophysiology defective,memory defective,tarsal response defective,chemical conditional,nutrition conditional,courtship behavior defective,male limited,learning defective,RU486 conditional" FBgn0265886 CR44675 - http://flybase.org/reports/FBgn0265886 non_protein_coding_gene - - - CR44675 - CR44675 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040652 CG15463 - http://flybase.org/reports/FBgn0040652 protein_coding_gene - - - CG15463 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024231 grr grater http://flybase.org/reports/FBgn0024231 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available grr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004030 wx waxy http://flybase.org/reports/FBgn0004030 - gene - - - "wxt, wx" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile,fertile" "wing,1st posterior cell,2nd posterior cell" FBgn0013588 l(3)97Dc lethal (3) 97Dc http://flybase.org/reports/FBgn0013588 - gene - - - l(3)97Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0267594 CR45932 - http://flybase.org/reports/FBgn0267594 pseudogene_attribute - - - "CR45932, CG40583" - CR45932 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040778 CG17977 - http://flybase.org/reports/FBgn0040778 protein_coding_gene - - - CG17977 - CG17977 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013989 Ms(3)R24 Ms(3)R24 http://flybase.org/reports/FBgn0013989 - gene - - - Ms(3)R24 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037778 mtTFB2 mitochondrial transcription factor B2 http://flybase.org/reports/FBgn0037778 protein_coding_gene "rRNA (adenine-N6,N6-)-dimethyltransferase activity ; GO:0000179 | inferred from biological aspect of ancestor with PANTHER:PTN000197843 transcription cofactor activity ; GO:0003712 | inferred from sequence or structural similarity with UniProtKB:Q9H5Q4" "transcription initiation from mitochondrial promoter ; GO:0006391 | inferred from electronic annotation with InterPro:IPR016861 regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR016861 rRNA methylation ; GO:0031167 | inferred from electronic annotation with InterPro:IPR016861 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype transcription from mitochondrial promoter ; GO:0006390 | inferred from mutant phenotype transcription from mitochondrial promoter ; GO:0006390 | inferred from sequence or structural similarity with UniProtKB:Q9H5Q4" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q9H5Q4 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000197847 mitochondrion ; GO:0005739 | inferred from direct assay "CG3910, d-mtTFB2, mtTFB2, d-TF2BM, TFB2, TFB2M" "IPR001737:Ribosomal RNA adenine methyltransferase KsgA/Erm, IPR016861:Mitochondrial transcription factor TFB2, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG3910 11-Aug-17 DroID_v2017_08 Drer\tfb2m "Scer\DIM1, Scer\MTF1" Cele\tfbm-1 - "Mmus\Isg15, Mmus\Tfb2m" Hsap\TFB2M "cell growth defective,viable,poor,developmental rate defective,small body,decreased cell number,increased cell death,lethal - all die before end of larval stage,some die during third instar larval stage" "embryonic/larval brain,wing disc" FBgn0029645 CG14422 - http://flybase.org/reports/FBgn0029645 protein_coding_gene - - - CG14422 - CG14422 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0010163 ms(Y)hd male sterile (Y) hybrid dysgenesis http://flybase.org/reports/FBgn0010163 - gene - - - ms(Y)hd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069142 mcl(3)Z5121 mcl(3)Z5121 http://flybase.org/reports/FBgn0069142 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z5121 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0029185 E(Khc)ek10 E(Khc)ek10 http://flybase.org/reports/FBgn0029185 gene - - - E(Khc)ek10 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031602 CG15431 - http://flybase.org/reports/FBgn0031602 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15431 - CG15431 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0014330 l(3)ry84 lethal (3) ry84 http://flybase.org/reports/FBgn0014330 - gene - - - l(3)ry84 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033187 PIG-G Phosphatidylinositol glycan anchor biosynthesis class G http://flybase.org/reports/FBgn0033187 protein_coding_gene CP2 mannose-ethanolamine phosphotransferase activity ; GO:0051267 | inferred from biological aspect of ancestor with PANTHER:PTN000552977 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000552977 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000552977 "CG2144, PIG-G" "IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR002591:Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase" CG2144 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-49o8.1, Drer\pigo" Scer\LAS21 "Cele\C27A12.9, Cele\F28C6.4" "Xtro\pigo, Xtro\pigg" "Mmus\Pigg, Mmus\Pigo" "Hsap\PIGO, Hsap\PIGG" viable FBgn0028563 sut1 sugar transporter 1 http://flybase.org/reports/FBgn0028563 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from electronic annotation with InterPro:IPR003663 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003663, InterPro:IPR005828, InterPro:IPR005829" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "CG8714, sut1, Sut1" "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG8714 11-Aug-17 DroID_v2017_08 "Drer\slc2a2, Drer\slc2a15a, Drer\LOC100334818, Drer\slc2a1a, Drer\slc2a9l1, Drer\slc2a11b, Drer\slc2a11l, Drer\slc2a11a, Drer\slc2a15b, Drer\slc2a3a, Drer\slc2a3b, Drer\slc2a1b, Drer\LOC100331510" "Scer\VPS73, Scer\YBR241C, Scer\HXT4, Scer\HXT14" "Cele\ZK829.9, Cele\K08H10.6, Cele\C35A11.4, Cele\Y37A1A.3, Cele\K09C4.1, Cele\K09C4.4, Cele\slcf-2, Cele\C03B1.13, Cele\Y39E4B.5, Cele\K09C4.5, Cele\F11D5.5, Cele\F53H8.3, Cele\K08F9.1, Cele\F48E3.2, Cele\F14E5.1, Cele\R09B5.11, Cele\Y39B6A.41, Cele\fgt-1, Cele\Y61A9LA.1, Cele\F11D5.7, Cele\F13B12.2" "Xtro\slc2a11, Xtro\slc2a2, Xtro\slc2a1, Xtro\slc2a3, Xtro\slc2a5, Xtro\slc2a7, Xtro\slc2a9, Xtro\LOC100496725" "Mmus\Slc2a7, Mmus\Slc2a1, Mmus\Slc2a2, Mmus\Slc2a3, Mmus\Slc2a5, Mmus\Slc2a4, Mmus\Slc2a9" "Hsap\SLC2A5, Hsap\SLC2A1, Hsap\SLC2A14, Hsap\SLC2A9, Hsap\SLC2A2, Hsap\SLC2A4, Hsap\SLC2A11, Hsap\SLC2A3, Hsap\MIF, Hsap\SLC2A7" "viable,fertile,neuroanatomy defective" neurite | pharate adult stage FBgn0032094 CG12439 - http://flybase.org/reports/FBgn0032094 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT16114, CG12439" IPR032145:Protein of unknown function DUF4818 CG12439 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002151 l(2)KX3 lethal (2) KX3 http://flybase.org/reports/FBgn0002151 - gene - - - l(2)KX3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032997 CG17486 - http://flybase.org/reports/FBgn0032997 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from biological aspect of ancestor with PANTHER:PTN000206333 asparagine synthase (glutamine-hydrolyzing) activity ; GO:0004066 | inferred from biological aspect of ancestor with PANTHER:PTN000206333 asparagine biosynthetic process ; GO:0006529 | inferred from biological aspect of ancestor with PANTHER:PTN000206333 - "CG40291, CG17486" "IPR001962:Asparagine synthase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR029055:Nucleophile aminohydrolases, N-terminal, IPR017932:Glutamine amidotransferase type 2 domain" CG17486 11-Aug-17 DroID_v2017_08 Drer\asnsd1 Scer\YML096W Cele\M18.3 Xtro\asnsd1 Mmus\Asnsd1 Hsap\ASNSD1 FBgn0024652 l(2)k08625 lethal (2) k08625 http://flybase.org/reports/FBgn0024652 - gene - - - "86/25, l(2)k08625" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083949 CG34113 - http://flybase.org/reports/FBgn0083949 protein_coding_gene - - - "CT34460, CG14678, CG14677, CG10989, CG34113, 34113, Dm_3R:9314" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain, IPR003598:Immunoglobulin subtype 2" CG34113 11-Aug-17 DroID_v2017_08 Drer\nphs1 - - Xtro\nphs1 Mmus\Nphs1 Hsap\NPHS1 "visible,partially lethal - majority die,some die during pupal stage,viable" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0263267 del2 - http://flybase.org/reports/FBgn0263267 gene - gonad development ; GO:0008406 | inferred from mutant phenotype - del2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "gonad,gonadal sheath proper primordium" FBgn0038658 CG14292 - http://flybase.org/reports/FBgn0038658 protein_coding_gene - - - CG14292 - CG14292 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0266984 CR45435 - http://flybase.org/reports/FBgn0266984 non_protein_coding_gene - - - "CR45435, lincRNA.611" - CR45435 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267525 CR45865 - http://flybase.org/reports/FBgn0267525 non_protein_coding_gene - - - CR45865 - CR45865 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053519 Unc-89 Unc-89 http://flybase.org/reports/FBgn0053519 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from electronic annotation with InterPro:IPR000219 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCA8 protein kinase binding ; GO:0019901 | inferred from physical interaction with UniProtKB:Q7KRY6 protein kinase activity ; GO:0004672 | NOT inferred from key residues tropomyosin binding ; GO:0005523 | inferred from physical interaction with UniProtKB:P06754" regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype protein localization to M-band ; GO:0036309 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | NOT inferred from key residues M band ; GO:0031430 | inferred from direct assay "CG33519, CG30171, CG18020, CG3901, CG18021, CT40326, CT40322, CT12925, BEST:HL01080, CG18019, CG30175, Unc-89, UNC-89, unc-89, obs" "IPR000719:Protein kinase domain, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR011009:Protein kinase-like domain, IPR000219:Dbl homology (DH) domain, IPR011993:PH domain-like, IPR013783:Immunoglobulin-like fold, IPR001452:SH3 domain, IPR003598:Immunoglobulin subtype 2, IPR013098:Immunoglobulin I-set" CG33519 11-Aug-17 DroID_v2017_08 "Drer\sc:d0284, Drer\spega, Drer\capsla, Drer\mylk4a, Drer\capslb, Drer\LOC100006752, Drer\mylk3, Drer\LOC101885775, Drer\stk17a, Drer\zgc:153952, Drer\camkvb, Drer\si:ch73-380l3.2, Drer\si:dkey-65j6.2, Drer\camk1b, Drer\mylkb, Drer\zgc:172106, Drer\camk1ga, Drer\si:dkey-240h12.4, Drer\si:ch73-60h1.1, Drer\camk1gb, Drer\stk33, Drer\triob, Drer\obscnb, Drer\spegb, Drer\camk1a, Drer\vwa10.2, Drer\vwa10.1, Drer\si:ch211-27e6.1, Drer\LOC100535144, Drer\zmp:0000000971, Drer\camk1db, Drer\si:ch211-1f22.3, Drer\LOC100333244, Drer\cd22, Drer\dapk2b, Drer\ttnb, Drer\LOC101884775, Drer\mylk4b, Drer\camkva, Drer\scospondin, Drer\stk17b, Drer\uhmk1, Drer\camkvl, Drer\dapk1, Drer\zgc:171470, Drer\LOC569231, Drer\obsl1b, Drer\obsl1a, Drer\hmcn2, Drer\quo, Drer\camk4, Drer\camk1da, Drer\dscama, Drer\si:ch211-171h4.5, Drer\pnck, Drer\dapk3, Drer\mylka, Drer\pskh1, Drer\vwa11, Drer\si:ch211-286b5.9, Drer\sestd1, Drer\vwa7, Drer\LOC100333105, Drer\zmp:0000001289, Drer\hmcn1, Drer\LOC100148735, Drer\dapk2a, Drer\trioa" "Scer\MEK1, Scer\RCK1, Scer\IKS1, Scer\TDA1, Scer\RCK2, Scer\CMK1, Scer\CMK2" "Cele\ZC373.4, Cele\ketn-1, Cele\unc-52, Cele\unc-89, Cele\unc-22, Cele\him-4" "Xtro\caps, Xtro\MGC89178, Xtro\camk1, Xtro\dscam, Xtro\mylk3, Xtro\kalrn, Xtro\capsl, Xtro\dclk2, Xtro\pnck, Xtro\pskh2, Xtro\dscaml1, Xtro\camk4, Xtro\camk1d, Xtro\sestd1, Xtro\stk17a, Xtro\hmcn2, Xtro\mylk, Xtro\stk33, Xtro\dapk3, Xtro\dapk1, Xtro\pskh1, Xtro\camk1g, Xtro\obsl1, Xtro\trio, Xtro\dapk2, Xtro\camkv, Xtro\mylk4" "Mmus\Mylk, Mmus\Obsl1, Mmus\Camk4, Mmus\Mylk3, Mmus\Hmcn2, Mmus\Dscam, Mmus\Mcf2, Mmus\Sestd1, Mmus\Kalrn, Mmus\Mylk2, Mmus\Trio, Mmus\Pnck, Mmus\Camk1g, Mmus\Camk1, Mmus\Camkv, Mmus\Capsl, Mmus\Dapk3, Mmus\Hmcn1, Mmus\Stk33, Mmus\Uhmk1, Mmus\Dclk2, Mmus\Camk1d, Mmus\Dclk1, Mmus\Dapk2, Mmus\Speg, Mmus\Alpk3, Mmus\Ptk7, Mmus\Vwa7, Mmus\Obscn, Mmus\Caps2, Mmus\Stk17b, Mmus\Pskh1, Mmus\Mylk4, Mmus\Dscaml1, Mmus\Ttn, Mmus\Dapk1" "Hsap\PLEKHG4B, Hsap\PSKH1, Hsap\HMCN2, Hsap\TTN, Hsap\CAMKV, Hsap\CAMK1G, Hsap\MYLK4, Hsap\SESTD1, Hsap\MYLK, Hsap\CAMK1D, Hsap\SPEG, Hsap\PSKH2, Hsap\ALPK3, Hsap\CAMK1, Hsap\MCF2L2, Hsap\DAPK1, Hsap\VWA7, Hsap\OBSCN, Hsap\DAPK2, Hsap\DCLK1, Hsap\STK17A, Hsap\DSCAML1, Hsap\PTK7, Hsap\PNCK, Hsap\CAMK4, Hsap\CAPS, Hsap\MYLK2, Hsap\DSCAM, Hsap\KALRN, Hsap\MCF2, Hsap\TRIO, Hsap\MYLK3, Hsap\STK17B, Hsap\OBSL1, Hsap\HMCN1, Hsap\CAPSL, Hsap\STK33, Hsap\CAPS2, Hsap\DAPK3, Hsap\UHMK1" "viable,flightless" "indirect flight muscle,M bandMef2.PR,sarcomere | pharate adult stageMef2.PR,myofibril | adult stageMef2.PR,indirect flight muscle | adult stage,H zone | adult stageMef2.PR,striated muscle thin filament | adult stageMef2.PR,myofibril | adult stageUH3,H zone | adult stageUH3,myofibril | adult stage,M band,H zone,striated muscle thin filament | adult stage" FBgn0021926 l(2)k11201 lethal (2) k11201 http://flybase.org/reports/FBgn0021926 - gene - - - l(2)k11201 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061009 l(3)S026222b lethal (3) S026222b http://flybase.org/reports/FBgn0061009 gene - - - "0262/22, l(3)S026222b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044517 ifm(2)RU536 indirect flight muscle (2) RU536 http://flybase.org/reports/FBgn0044517 gene - - - "RU536, ifm(2)RU536" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,sterile,partially,recessive,flight defective" "wing,indirect flight muscle" FBgn0034419 CG15111 - http://flybase.org/reports/FBgn0034419 protein_coding_gene - - - CG15111 "IPR029058:Alpha/Beta hydrolase fold, IPR022742:Serine aminopeptidase, S33" CG15111 11-Aug-17 DroID_v2017_08 "Drer\abhd12, Drer\si:ch211-117n7.7, Drer\si:ch211-117n7.6" Scer\YNL320W Cele\abhd-12 Xtro\abhd12 "Mmus\Abhd12b, Mmus\Abhd12" "Hsap\ABHD12, Hsap\ABHD12B" lethal FBgn0267208 CR45648 - http://flybase.org/reports/FBgn0267208 non_protein_coding_gene - - - CR45648 - CR45648 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086340 upd1::upd2 - http://flybase.org/reports/FBgn0086340 engineered_fusion_gene - - - "os::upd2, upd1::upd2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040775 CG12158 - http://flybase.org/reports/FBgn0040775 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BcDNA:RH45738, anon-WO0153538.61, CG12158" - CG12158 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0035848 CG7979 - http://flybase.org/reports/FBgn0035848 protein_coding_gene NAD+ binding ; GO:0070403 | inferred from biological aspect of ancestor with PANTHER:PTN000041126 UDP-glucuronate decarboxylase activity ; GO:0048040 | inferred from biological aspect of ancestor with PANTHER:PTN000041126 - cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000041126 "CG7979, Uxs" IPR016040:NAD(P)-binding domain CG7979 11-Aug-17 DroID_v2017_08 Drer\uxs1 "Scer\GAL10, Scer\GRE2" "Cele\F53B1.4, Cele\sqv-1" Xtro\uxs1 "Mmus\Uxs1, Mmus\Tgds" "Hsap\TGDS, Hsap\UXS1" viable FBgn0085342 CG34313 - http://flybase.org/reports/FBgn0085342 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34313, CG4826" - CG34313 11-Aug-17 DroID_v2017_08 Drer\snrnp25 - - Xtro\snrnp25 Mmus\Snrnp25 Hsap\SNRNP25 FBgn0034636 twz tiwaz http://flybase.org/reports/FBgn0034636 protein_coding_gene - protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype adult feeding behavior ; GO:0008343 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype - "CG10440, Twz, twz" "IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR011333:SKP1/BTB/POZ domain" CG10440 11-Aug-17 DroID_v2017_08 "Drer\kctd14, Drer\kctd12b, Drer\kctd15a, Drer\kctd4, Drer\kctd12.1, Drer\kctd6a, Drer\kctd12.2, Drer\kctd16b, Drer\kctd6b, Drer\kctd7, Drer\kctd1, Drer\kctd15b" - "Cele\ZC239.6, Cele\ZC239.3" "Xtro\kctd6, Xtro\kctd14, Xtro\kctd7, Xtro\kctd1, Xtro\kctd15, Xtro\kcnrg, Xtro\kctd8, Xtro\kctd12" "Mmus\Kctd15, Mmus\Kctd21, Mmus\Kctd16, Mmus\Kcnrg, Mmus\Kctd12b, Mmus\Kctd7, Mmus\Kctd4, Mmus\Kctd18, Mmus\Kctd1, Mmus\Kctd6, Mmus\Kctd11, Mmus\Kctd19, Mmus\Kctd8, Mmus\Kctd14" "Hsap\KCTD16, Hsap\KCTD14, Hsap\KCTD1, Hsap\KCTD4, Hsap\KCNRG, Hsap\KCTD15, Hsap\KCTD6, Hsap\KCTD19, Hsap\KCTD18, Hsap\KCTD11, Hsap\KCTD8, Hsap\KCTD12, Hsap\KCTD21" viable FBgn0086069 snoRNA:Me28S-C3351 - http://flybase.org/reports/FBgn0086069 snoRNA_gene - - - "snoRNA:Me28S-C3351, Me28S-Cm3351, Me28S-C3351, CR34698" - CR34698 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052756 CG32756 - http://flybase.org/reports/FBgn0052756 protein_coding_gene molecular_function ; GO:0003674 | no biological data available double-strand break repair ; GO:0006302 | inferred from electronic annotation with InterPro:IPR015381 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR015381 "BcDNA:LD29716, CG32756" IPR015381:XLF family CG32756 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039738 Mgat2 Mgat2 http://flybase.org/reports/FBgn0039738 protein_coding_gene "alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity ; GO:0008455 | inferred from electronic annotation with InterPro:IPR007754 acetylglucosaminyltransferase activity ; GO:0008375 | inferred from direct assay" oligosaccharide biosynthetic process ; GO:0009312 | inferred from electronic annotation with InterPro:IPR007754 protein N-linked glycosylation ; GO:0006487 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007754 Golgi medial cisterna ; GO:0005797 | inferred from direct assay "dMGAT2, CG7921, GlcNAc-TII, Mgat2, GlcNAcT2" "IPR007754:N-acetylglucosaminyltransferase II, IPR029044:Nucleotide-diphospho-sugar transferases" CG7921 11-Aug-17 DroID_v2017_08 "Drer\LOC100536673, Drer\mgat2" - Cele\gly-20 Xtro\mgat2 Mmus\Mgat2 Hsap\MGAT2 "viable,fertile" FBgn0015801 Reg-5 Rhythmically expressed gene 5 http://flybase.org/reports/FBgn0015801 - protein_coding_gene - - - "CG2928, dreg-5, Dreg5, reg-5, Dreg-5, DREG-5, Dreg, Reg-5" - CG2928 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , embryonic stage | late " adult head

FBgn0266507 s-409 - http://flybase.org/reports/FBgn0266507 gene - - - s-409 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010193 tu-wps tu-wps http://flybase.org/reports/FBgn0010193 - gene - - - tu-wps - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041633 F-element\RTase F element reverse transcriptase http://flybase.org/reports/FBgn0041633 transposable_element_gene - - - "ORF2, F-ORF2, F\ORF2, F-element\RTase" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , adult stage && oogenesis stage , embryonic stage | blastoderm " " embryonic/larval foregut

, embryonic central nervous system

, testis

, embryonic/larval salivary gland

, embryonic/larval tracheal system

, nurse cell

,

posterior , amnioserosa

, embryonic/larval muscle system

, follicle cell

" FBgn0037614 TMEM216 - http://flybase.org/reports/FBgn0037614 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:25018 cilium ; GO:0005929 | inferred from sequence or structural similarity with HGNC:25018 "GH04517, EP(3)3246, TMEM216, CG8116" "IPR019184:Uncharacterised protein family, transmembrane-17" CG8116 11-Aug-17 DroID_v2017_08 Drer\si:rp71-1d10.5 - "Cele\C30B5.6, Cele\mks-2" Xtro\tmem216 "Mmus\Tmem216, Mmus\Tmem80" "Hsap\TMEM80, Hsap\TMEM216" viable FBgn0261624 I-3 Inhibitor-3 http://flybase.org/reports/FBgn0261624 protein_coding_gene protein serine/threonine phosphatase inhibitor activity ; GO:0004865 | inferred from biological aspect of ancestor with PANTHER:PTN000464544 protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B negative regulation of phosphoprotein phosphatase activity ; GO:0032515 | inferred from biological aspect of ancestor with PANTHER:PTN000464544 protein phosphatase type 1 complex ; GO:0000164 | inferred from biological aspect of ancestor with PANTHER:PTN000464544 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000464544 "CG11233, I-3, CG42707" IPR011107:Protein phosphatase inhibitor CG42707 11-Aug-17 DroID_v2017_08 Drer\ppp1r11 Scer\YPI1 "Cele\ZK945.8, Cele\K10H10.7, Cele\C07H6.2" Xtro\ppp1r11 Mmus\Ppp1r11 Hsap\PPP1R11 "partially lethal - majority die,some die during pupal stage" FBgn0262949 CG43268 - http://flybase.org/reports/FBgn0262949 protein_coding_gene - - - CG43268 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033668 exp expansion http://flybase.org/reports/FBgn0033668 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001132 trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype transmembrane receptor protein tyrosine phosphatase signaling pathway ; GO:0007185 | inferred from genetic interaction with Egfr inferred from genetic interaction with btl chitin biosynthetic process ; GO:0006031 | inferred from mutant phenotype cuticle chitin biosynthetic process ; GO:0006035 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay "CG13188, exp, Exp" "IPR001132:SMAD domain, Dwarfin-type, IPR008984:SMAD/FHA domain, IPR017855:SMAD domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG13188 11-Aug-17 DroID_v2017_08 - - Cele\C34E11.2 - Mmus\Smad2 Hsap\SMAD2 lethal DRSC06313 IK -3.064495935 -3.400983671 -1.034571325 0.814511833 4.510866299 6.581515142 FBgn0014198 l(1)14Ce lethal (1) 14Ce http://flybase.org/reports/FBgn0014198 - gene - - - "l(1)14Cf, l(1)14Ce" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0267627 CR45965 - http://flybase.org/reports/FBgn0267627 non_protein_coding_gene - - - CR45965 - CR45965 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035207 Sherpa SUMO-related HECT domain and RCC repeat protein for Toll pathway activation http://flybase.org/reports/FBgn0035207 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:4868 protein autoubiquitination ; GO:0051865 | inferred from direct assay protein ubiquitination ; GO:0016567 | inferred from direct assay positive regulation of protein localization to plasma membrane ; GO:1903078 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:4868 positive regulation of MyD88-dependent toll-like receptor signaling pathway ; GO:0034126 | inferred from mutant phenotype inferred from genetic interaction with tub inferred from genetic interaction with pll inferred from physical interaction with Myd88 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:4868 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:4868 "FBgn0035207, CG9153, NM_167868.1, Sherpa, sherpa" "IPR000408:Regulator of chromosome condensation, RCC1, IPR000569:HECT domain, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG9153 11-Aug-17 DroID_v2017_08 "Drer\herc3, Drer\si:ch211-281g13.4, Drer\si:ch211-281g13.5, Drer\herc4, Drer\hectd2, Drer\si:ch73-190m4.1, Drer\zgc:163136, Drer\ube3a" "Scer\HUL4, Scer\FMP25" Cele\herc-1 "Xtro\herc4, Xtro\herc6, Xtro\herc3, Xtro\ube3a" "Mmus\Herc6, Mmus\Herc4, Mmus\Herc3, Mmus\Hectd2, Mmus\Ube3a" "Hsap\HERC5, Hsap\HERC3, Hsap\HECTD2, Hsap\HERC4, Hsap\HERC6, Hsap\UBE3A" viable FBgn0031137 CG11230 - http://flybase.org/reports/FBgn0031137 protein_coding_gene - - - CG11230 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262106 CR42859 - http://flybase.org/reports/FBgn0262106 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR42859 - CR42859 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024912 agt O-6-alkylguanine-DNA alkyltransferase http://flybase.org/reports/FBgn0024912 - protein_coding_gene methylated-DNA-[protein]-cysteine S-methyltransferase activity ; GO:0003908 | inferred from direct assay DNA dealkylation involved in DNA repair ; GO:0006307 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000743963 "DmAGT, CG1303, BG:DS00004.10, agt, Agt" "IPR001497:Methylated-DNA-[protein]-cysteine S-methyltransferase, active site, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR014048:Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding" CG1303 11-Aug-17 DroID_v2017_08 Drer\mgmt Scer\MGT1 Cele\agt-1 Xtro\mgmt Mmus\Mgmt Hsap\MGMT viable DRSC12611 E 0.106768208 0.142452694 1.596707663 -0.001131458 0.221999864 0.865718086 FBgn0002005 l(2)36Bd lethal (2) 36Bd http://flybase.org/reports/FBgn0002005 - gene - - - "l(2L)HT-2, l(2)HT-2, l(2)36Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051635 CG31635 - http://flybase.org/reports/FBgn0051635 protein_coding_gene - - - "CG13769, CT33252, CG13768, BcDNA:GM03875, CG31635" "IPR032675:Leucine-rich repeat domain, L domain-like" CG31635 11-Aug-17 DroID_v2017_08 "Drer\lrrc16b, Drer\si:dkey-288a3.2, Drer\rltpr, Drer\ppp1r37" - "Cele\crml-1, Cele\F28C1.3" Xtro\ppp1r37 "Mmus\Rnh1, Mmus\Carmil1, Mmus\Ppp1r37, Mmus\Carmil2, Mmus\Carmil3" "Hsap\CARMIL2, Hsap\RNH1, Hsap\CARMIL1, Hsap\CARMIL3, Hsap\PPP1R37" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0030931 Xrcc2 X-ray repair cross complementing 2 http://flybase.org/reports/FBgn0030931 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 DNA-dependent ATPase activity ; GO:0008094 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 four-way junction DNA binding ; GO:0000400 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 endodeoxyribonuclease activity ; GO:0004520 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from sequence or structural similarity with HGNC:12829 reciprocal meiotic recombination ; GO:0007131 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 mitotic recombination ; GO:0006312 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with HGNC:12829 meiotic DNA recombinase assembly ; GO:0000707 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 regulation of cell cycle ; GO:0051726 | inferred from direct assay strand invasion ; GO:0042148 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 response to ionizing radiation ; GO:0010212 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 DNA recombination ; GO:0006310 | inferred from sequence or structural similarity with HGNC:12829 replication fork ; GO:0005657 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 Rad51B-Rad51C-Rad51D-XRCC2 complex ; GO:0033063 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 "Dm CG6318, CG6318, dmRad51D, Rad51D, Xrcc2" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR030547:DNA repair protein XRCC2" CG6318 11-Aug-17 DroID_v2017_08 Drer\xrcc2 - Cele\rad-51 Xtro\xrcc2 Mmus\Xrcc2 Hsap\XRCC2 viable FBgn0005044 E(var)33AD Enhancer of variegation 33AD http://flybase.org/reports/FBgn0005044 - gene - - - "E(var)33A-D, E(var)33AD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060427 l(3)S126201 lethal (3) S126201 http://flybase.org/reports/FBgn0060427 gene - - - "1262/01, l(3)S126201" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265791 CR44580 - http://flybase.org/reports/FBgn0265791 non_protein_coding_gene - - - "lincRNA.99, CR44580" - CR44580 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265215 fs(2)Z2-1071 - http://flybase.org/reports/FBgn0265215 gene - - - fs(2)Z2-1071 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0025778 fs(3)85Aa fs(3)85Aa http://flybase.org/reports/FBgn0025778 - gene - - - fs(3)85Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037900 CG5276 - http://flybase.org/reports/FBgn0037900 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR009283 uridine-diphosphatase activity ; GO:0045134 | inferred from biological aspect of ancestor with PANTHER:PTN000989481 nucleoside-diphosphatase activity ; GO:0017110 | inferred from direct assay nucleoside-triphosphatase activity ; GO:0017111 | inferred from direct assay guanosine-diphosphatase activity ; GO:0004382 | inferred from biological aspect of ancestor with PANTHER:PTN000989481 proteoglycan biosynthetic process ; GO:0030166 | inferred from biological aspect of ancestor with PANTHER:PTN000989481 - CG5276 IPR009283:Apyrase CG5276 11-Aug-17 DroID_v2017_08 "Drer\cant1a, Drer\cant1b" - "Cele\ZK563.7, Cele\apy-1" Xtro\cant1 Mmus\Cant1 Hsap\CANT1 viable FBgn0259189 Ir7e Ionotropic receptor 7e http://flybase.org/reports/FBgn0259189 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG15327, DmelIR7e, CG42293, Ir7e, IR7e" - CG42293 11-Aug-17 DroID_v2017_08 "Drer\grid1a, Drer\LOC100537813, Drer\grid1b" - - - "Mmus\Grid1, Mmus\Grik2, Mmus\Grik4" "Hsap\GRIN2C, Hsap\GRID1, Hsap\GRIK2, Hsap\GRIK3, Hsap\GRID2" DRSC18011 I 0.139069486 2.281763043 -0.21270757 0.578926646 -0.32600755 0.245387937 FBgn0035825 CG8111 - http://flybase.org/reports/FBgn0035825 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8111 IPR012430:Transmembrane protein 43 family CG8111 11-Aug-17 DroID_v2017_08 "Drer\LOC101882355, Drer\tmem43" - Cele\T12A7.9 Xtro\tmem43 Mmus\Tmem43 Hsap\TMEM43 viable FBgn0030603 CG5541 - http://flybase.org/reports/FBgn0030603 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of pain ; GO:0019233 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG5541, 5541" "IPR032675:Leucine-rich repeat domain, L domain-like" CG5541 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0062523 l(3)88EFi lethal (3) 88EFi http://flybase.org/reports/FBgn0062523 gene - - - l(3)88EFi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267673 CR46009 - http://flybase.org/reports/FBgn0267673 non_protein_coding_gene - - - CR46009 - CR46009 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265153 CR44222 - http://flybase.org/reports/FBgn0265153 non_protein_coding_gene - - - CR44222 - CR44222 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032880 TM9SF2 Transmembrane 9 superfamily protein member 2 http://flybase.org/reports/FBgn0032880 protein_coding_gene - negative regulation of peptidoglycan recognition protein signaling pathway ; GO:0061060 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000080197 cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "38E.10, CG9318, TM9SF2" IPR004240:Nonaspanin (TM9SF) CG9318 11-Aug-17 DroID_v2017_08 "Drer\tm9sf4, Drer\top3a, Drer\LOC558202, Drer\tm9sf2" "Scer\TMN3, Scer\TMN2, Scer\EMP70" "Cele\ZK858.6, Cele\top-3, Cele\tag-123" "Xtro\tm9sf2, Xtro\top3a, Xtro\LOC100489507" "Mmus\Tm9sf4, Mmus\Top3a, Mmus\Tm9sf2, Mmus\Gm364" "Hsap\TM9SF2, Hsap\TOP3A, Hsap\TM9SF4" DRSC03197 IE 2.611157848 1.22374813 -0.15187333 -2.23943471 -0.187120013 0.132843035 FBgn0261618 larp La related protein http://flybase.org/reports/FBgn0261618 protein_coding_gene - autophagic cell death ; GO:0048102 | inferred from expression pattern spindle assembly involved in male meiosis ; GO:0007053 | inferred from mutant phenotype mitochondrion inheritance ; GO:0000001 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay "CG42551, CG14065, CG14066, Larp, BcDNA:LD02611, larp, dlarp, 0031/08, l(3)S003108, 0225/29, l(3)S022529, larp1" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR006607:Protein of unknown function DM15, IPR006630:RNA-binding protein Lupus La, IPR011991:Winged helix-turn-helix DNA-binding domain" CG42551 11-Aug-17 DroID_v2017_08 "Drer\larp1b, Drer\larp1" "Scer\SLF1, Scer\SRO9" Cele\larp-1 "Xtro\larp1, Xtro\larp1b" "Mmus\Larp1b, Mmus\Larp4, Mmus\Larp1" "Hsap\LARP1B, Hsap\LARP1" FBgn0037883 CG14701 - http://flybase.org/reports/FBgn0037883 protein_coding_gene metal ion binding ; GO:0046872 | inferred from sequence or structural similarity with SGD:S000007587 peptidyl-diphthamide biosynthetic process from peptidyl-histidine ; GO:0017183 | inferred from sequence or structural similarity with SGD:S000007587 "cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:27717,SGD:S000007587 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:27717,SGD:S000007587" CG14701 "IPR007872:Zinc finger, DPH-type" CG14701 11-Aug-17 DroID_v2017_08 "Drer\dnajc24, Drer\dph3" Scer\KTI11 Cele\dph-3 "Xtro\dnajc24, Xtro\dph3" Mmus\Dph3 "Hsap\DPH3, Hsap\DPH3P1" viable DRSC25545 K 0.290218447 0.242628529 -0.271400905 -0.011221198 0.64787305 2.491559383 FBgn0034523 Nnf1a Nnf1a http://flybase.org/reports/FBgn0034523 protein_coding_gene - mitotic metaphase plate congression ; GO:0007080 | inferred from genetic interaction with Nnf1b chromosome segregation ; GO:0007059 | inferred from genetic interaction with Nnf1b Ndc80 complex ; GO:0031262 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay NMS complex ; GO:0031617 | inferred from sequence or structural similarity with HGNC:9112 "Nnf1a, CG13434, dmNnf1R-2" - CG13434 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage" "metaphase,trichogen cell,mesothoracic tergum" FBgn0030257 SmydA-4 "SET and MYND domain containing, arthropod-specific, member 4" http://flybase.org/reports/FBgn0030257 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "SmydA-4, CG11160" IPR001214:SET domain CG11160 11-Aug-17 DroID_v2017_08 "Drer\smyd1b, Drer\erlin2, Drer\smyd3, Drer\smyd2a, Drer\smyd1a, Drer\smyd2b, Drer\smyd4, Drer\erlin1" "Scer\SET6, Scer\SET5" "Cele\erl-1, Cele\set-18" "Xtro\smyd1, Xtro\smyd4, Xtro\erlin1, Xtro\erlin2, Xtro\smyd5" "Mmus\Erlin2, Mmus\Smyd4, Mmus\Erlin1, Mmus\Smyd3, Mmus\Smyd5, Mmus\Smyd2, Mmus\Smyd1" "Hsap\SMYD5, Hsap\SMYD2, Hsap\ERLIN1, Hsap\SMYD4, Hsap\SMYD1, Hsap\SMYD3" viable FBgn0262873 Diedel2 Diedel 2 http://flybase.org/reports/FBgn0262873 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from sequence or structural similarity with Diedel "Chr3R_25434193_25434663.0, Diedel2, CG43228, Diedel-2" IPR025061:Diedel CG43228 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011178 l(1)291-69 lethal (1) 291-69 http://flybase.org/reports/FBgn0011178 FBgn0010199 gene - - - "291-69, l(1)291-69" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004858 elB elbow B http://flybase.org/reports/FBgn0004858 FBgn0000569 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein binding ; GO:0005515 | inferred from physical interaction with gro inferred from physical interaction with noc leg disc development ; GO:0035218 | NOT inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype compound eye photoreceptor fate commitment ; GO:0001752 | inferred from genetic interaction with noc negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from genetic interaction with noc imaginal disc-derived appendage development ; GO:0048737 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype nucleolus ; GO:0005730 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity "elB, el, elbow, P10, elb, BG:DS06238.3, CG4220, el[B], Elbow, Elb, ElB" IPR013087:Zinc finger C2H2-type CG4220 11-Aug-17 DroID_v2017_08 "Drer\LOC100333111, Drer\znf703, Drer\znf503" - Cele\tlp-1 "Xtro\znf503, Xtro\znf703" "Mmus\Zfp503, Mmus\Zfp703" "Hsap\ZNF703, Hsap\ZNF503" "viable,poor,fertile,visible,recessive,lethal,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" "retina,visceral branch primordium,transverse connective primordium,dorsal branch primordium,eye,adult thorax,dorsocentral bristle,scutellar bristle,supernumerary,ectopic,wing vein,wing,alula,alula & macrochaeta,posterior,wing vein L5,2nd posterior cell,lateral trunk anterior branch,ganglionic branch primordium" DRSC25039 K -0.255914615 0.194802106 0.001762972 -0.120040234 1.56255525 -0.643806941 FBgn0035176 CG13905 - http://flybase.org/reports/FBgn0035176 protein_coding_gene - - - CG13905 IPR010629:Insect allergen-related CG13905 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08376 I -1.967841342 -0.024815118 -0.599012349 0.307112628 -0.354411661 -1.297281064 FBgn0265377 CR44318 - http://flybase.org/reports/FBgn0265377 non_protein_coding_gene - - - CR44318 - CR44318 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011248 ms(3)85D male sterile (3) 85D http://flybase.org/reports/FBgn0011248 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(3)03565, ms(3)ry85D, ms(3)85D" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0086357 Sec61alpha Sec61 alpha subunit http://flybase.org/reports/FBgn0086357 protein_coding_gene - protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR002208 dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from mutant phenotype cellular response to virus ; GO:0098586 | inferred from mutant phenotype positive regulation of viral entry into host cell ; GO:0046598 | inferred from mutant phenotype positive regulation of cell death ; GO:0010942 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype positive regulation of iron ion transmembrane transport ; GO:0034761 | inferred from mutant phenotype negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002208 endomembrane system ; GO:0012505 | inferred from direct assay rough endoplasmic reticulum ; GO:0005791 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "E(br)165, Sec61a, Sec61alpha, Sec61, sec61, endd2, DSec61alpha, LD29847, l(2)k04917, 0455, CG9539, BcDNA:LD29847, BEST:LD29847, anon-WO0118547.277, anon-WO0118547.195, sec61alpha, SEC61ALPHA, Sec61-alpha, SEC61-alpha, dSec61alpha, dSEC61A" "IPR002208:SecY/SEC61-alpha family, IPR030659:SecY conserved site, IPR019561:Translocon Sec61/SecY, plug domain, IPR023201:SecY subunit domain" CG9539 11-Aug-17 DroID_v2017_08 "Drer\uap1l1, Drer\uap1, Drer\sec61a1l, Drer\sec61a1" "Scer\SSH1, Scer\SEC61" "Cele\hhat-2, Cele\C36A4.4, Cele\sec-61" "Xtro\uap1, Xtro\sec61a1" "Mmus\Uap1l1, Mmus\Uap1, Mmus\Sec61a2, Mmus\Sec61a1" "Hsap\UAP1L1, Hsap\SEC61A1, Hsap\SEC61A2" DRSC03256 I -0.14783743 -2.165211788 0.816392152 -0.456150298 0.313677613 0.912290545 FBgn0032197 CG5694 - http://flybase.org/reports/FBgn0032197 protein_coding_gene - - - CG5694 "IPR019525:Nuclear respiratory factor 1, NLS/DNA-binding, dimerisation domain" CG5694 11-Aug-17 DroID_v2017_08 Drer\nrf1 - - - Mmus\Nrf1 Hsap\NRF1 "female fertile,viable,female semi-sterile" DRSC02879 IE 1.62044715 -0.327838686 2.031053711 1.083595578 0.397932217 -0.485919662 FBgn0052656 Muc11A Mucin 11A http://flybase.org/reports/FBgn0052656 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "CG2779, Muc11A, CG32656" IPR002557:Chitin binding domain CG32656 11-Aug-17 DroID_v2017_08 "Drer\zgc:111983, Drer\e2f7, Drer\e2f8, Drer\col8a2, Drer\col10a1a" Scer\HKR1 "Cele\clec-122, Cele\Y53C10A.10" "Xtro\e2f7, Xtro\col4a5, Xtro\e2f8" "Mmus\E2f7, Mmus\Col25a1, Mmus\Col9a1, Mmus\E2f8" "Hsap\COL9A1, Hsap\APOBR, Hsap\E2F8, Hsap\E2F7" viable FBgn0037736 CG12950 - http://flybase.org/reports/FBgn0037736 protein_coding_gene - - - "CT32101, CG12950, 12950" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold" CG12950 11-Aug-17 DroID_v2017_08 Drer\nphs1 - - Xtro\nphs1 "Mmus\Nphs1, Mmus\Skint8, Mmus\Gm1123, Mmus\Skint3, Mmus\Fcrls, Mmus\Btnl10, Mmus\Btnl2" "Hsap\CD276, Hsap\FCRL1, Hsap\NPHS1, Hsap\BTNL2, Hsap\BTN3A1, Hsap\SIRPA, Hsap\SIRPG, Hsap\PSG1, Hsap\SIRPB1, Hsap\MERTK" viable FBgn0065558 l(2)SH0998 lethal (2) SH0998 http://flybase.org/reports/FBgn0065558 gene - - - "l(2)SH0998, l(2)SH2 0998" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085191 CG34162 - http://flybase.org/reports/FBgn0085191 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34162 - CG34162 11-Aug-17 DroID_v2017_08 - - - - Mmus\Slc8b1 Hsap\SLC8B1 FBgn0035413 CG14958 - http://flybase.org/reports/FBgn0035413 protein_coding_gene - - - CG14958 - CG14958 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038511 cysu Curly Su http://flybase.org/reports/FBgn0038511 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 - "Q9VEJ9, cysu, CG5873" "IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal" CG5873 11-Aug-17 DroID_v2017_08 "Drer\ptgs1, Drer\igsf9bb, Drer\ptgs2b, Drer\ptgs2a, Drer\pxdn, Drer\epx, Drer\tpo" - "Cele\skpo-2, Cele\R08F11.7, Cele\skpo-1, Cele\K10B4.1, Cele\T06D8.10, Cele\C46A5.4, Cele\mlt-7, Cele\pxn-1, Cele\pxn-2, Cele\F09F3.5" "Xtro\ptgs1, Xtro\ptgs2, Xtro\tpo, Xtro\mpo, Xtro\pxdn, Xtro\epx" "Mmus\Lpo, Mmus\Epx, Mmus\Tpo, Mmus\Pxdn, Mmus\Mpo, Mmus\Ptgs1, Mmus\Ptgs2" "Hsap\EPX, Hsap\LPO, Hsap\TPO, Hsap\PTGS2, Hsap\MPO, Hsap\PXDNL, Hsap\PTGS1, Hsap\PXDN" "viable,fertile,visible" mesothoracic tergum FBgn0260396 CG42521 - http://flybase.org/reports/FBgn0260396 protein_coding_gene - - - "CG34237, CG42521" - CG42521 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005291 mei-2199 meiotic 2199 http://flybase.org/reports/FBgn0005291 - gene - - - "2199, mei-2199" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0265673 CR44480 - http://flybase.org/reports/FBgn0265673 non_protein_coding_gene - - - "lincRNA.113, CR44480" - CR44480 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013256 E(var)31 E(var)31 http://flybase.org/reports/FBgn0013256 - gene - - - E(var)31 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0266616 CR45123 - http://flybase.org/reports/FBgn0266616 non_protein_coding_gene - - - CR45123 - CR45123 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030293 CG1737 - http://flybase.org/reports/FBgn0030293 protein_coding_gene - - - CG1737 - CG1737 11-Aug-17 DroID_v2017_08 "Drer\vgll4l, Drer\vgll4b" - - Xtro\vgll4 Mmus\Vgll4 Hsap\VGLL4 "viable,female fertile" DRSC25132 IEK -1.510745975 -1.068864618 -2.614485252 0.100837421 1.566226248 2.866698462 FBgn0052834 CG32834 - http://flybase.org/reports/FBgn0052834 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000669108 "SPH196, CG9898, CG30331, CG32834" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG32834 11-Aug-17 DroID_v2017_08 "Drer\prozb, Drer\zgc:163025, Drer\proca, Drer\proza" - - - "Mmus\Klk13, Mmus\Proc, Mmus\Klk14, Mmus\Egfbp2, Mmus\Klk1b3, Mmus\Klk7, Mmus\Proz, Mmus\Klk1b8" "Hsap\KLK13, Hsap\PROZ, Hsap\PROC" "viable,mating behavior defective,female limited,female semi-sterile" FBgn0084462 W55 W55 http://flybase.org/reports/FBgn0084462 gene - - - W55 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,sterile" eye FBgn0004013 whh white head http://flybase.org/reports/FBgn0004013 - gene - - - whh - - 11-Aug-17 DroID_v2017_08 - - - - - - ocellus FBgn0034966 CG13563 - http://flybase.org/reports/FBgn0034966 protein_coding_gene - - - CG13563 - CG13563 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC22153 K 0.690905381 0.395710815 0.273329582 0.027887532 -0.486790458 -2.142991791 FBgn0030647 CG6324 - http://flybase.org/reports/FBgn0030647 protein_coding_gene - - - CG6324 IPR015943:WD40/YVTN repeat-like-containing domain CG6324 11-Aug-17 DroID_v2017_08 Drer\marco - Cele\pqn-65 - "Mmus\Marco, Mmus\Rptn" "Hsap\MARCO, Hsap\RPTN" viable FBgn0043539 Obp22a Odorant-binding protein 22a http://flybase.org/reports/FBgn0043539 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "22a, Obp-b, anon-AE003584.1, CG31941, Obp22a, DmelObp22a, obp22" IPR006170:Pheromone/general odorant binding protein CG31941 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003971 vb vibrissae http://flybase.org/reports/FBgn0003971 - gene - - - vb - - 11-Aug-17 DroID_v2017_08 - - - - - - vibrissae FBgn0034820 CG13538 - http://flybase.org/reports/FBgn0034820 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13538 - CG13538 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC04180 I 1.808360946 0.35740203 -0.139231984 -0.229628608 -0.354008741 -0.740237048 FBgn0013695 mt:tRNA:His-GTG mitochondrial transfer RNA:Histidine-GTG http://flybase.org/reports/FBgn0013695 FBgn0002867 tRNA_gene - - - "CR34084, mtdbD00006308, mt:tRNA:His-GTG, mt:tRNA:H, tRNA-his" - CR34084 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262624 Tmhs Tetraspan membrane protein in hair cell stereocilia http://flybase.org/reports/FBgn0262624 protein_coding_gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - "CG12026, Tmhs, TMHS" IPR019372:Lipoma HMGIC fusion partner-like protein CG12026 11-Aug-17 DroID_v2017_08 "Drer\lhfpl3, Drer\lhfpl5a, Drer\lhfpl4a, Drer\lhfpl2a, Drer\lhfpl4b, Drer\lhfp, Drer\lhfpl5b, Drer\lhfp, Drer\lhfpl2b" - Cele\lhfp-4 "Xtro\lhfpl3, Xtro\lhfpl2, Xtro\lhfpl5, Xtro\lhfpl4, Xtro\lhfpl1, Xtro\lhfp" "Mmus\Lhfp, Mmus\Lhfpl4, Mmus\Lhfpl2, Mmus\Lhfpl3, Mmus\Lhfpl1, Mmus\Lhfpl5, Mmus\Tmem211" "Hsap\LHFP, Hsap\LHFPL2, Hsap\LHFPL1, Hsap\LHFPL5, Hsap\LHFPL4, Hsap\TMEM211, Hsap\LHFPL3" FBgn0050452 tRNA:iMet-CAT-1-1 transfer RNA:initiator Methionine-CAT 1-1 http://flybase.org/reports/FBgn0050452 tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "CR30452, AE002787.trna7-MetCAT, tRNA:met3:56EF, tRNA:M3:56EF, tRNA:M:CAT:AE002787-a, CR30216, tRNA[Met-ATG], chr2R.trna65-MetCAT, tRNA-iMet-CAT-1-1, tRNA:iMet-CAT-1-1, tRNA:CR30452" - CR30452 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003202 rar2 radiation-resistant on 2 http://flybase.org/reports/FBgn0003202 - gene - - - rar2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011867 tRNA:Gly-GCC-1-8 transfer RNA:Glycine-GCC 1-8 http://flybase.org/reports/FBgn0011867 "FBgn0050236, FBgn0060217" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "AE002787.trna44-GlyGCC, tRNA:G:GCC:AE002787-b, CR30236, tRNA:gly3:53E, tRNA[Gly-GCC], chr2R.trna27-GlyGCC, tRNA-Gly-GCC-1-8, tRNA:Gly-GCC-1-8, tRNA:G3:53E, GGC" - CR30236 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261853 CG42782 - http://flybase.org/reports/FBgn0261853 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42782 - CG42782 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015568 alpha-Est1 alpha-Esterase-1 http://flybase.org/reports/FBgn0015568 - protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG1031, alphaE1, aE1, A, alpha-Est1, DmalphaE1, Est1, alpha est1, Alpha-Est1, Q9VIC3_DROME" "IPR029058:Alpha/Beta hydrolase fold, IPR002018:Carboxylesterase, type B" CG1031 11-Aug-17 DroID_v2017_08 "Drer\nlgn3b, Drer\nlgn4a, Drer\nlgn2a, Drer\ces2, Drer\ces3, Drer\nlgn4b, Drer\nlgn2b, Drer\nlgn3a, Drer\nlgn1, Drer\si:ch211-93f2.1, Drer\cel.1, Drer\cell" - "Cele\K11G9.2, Cele\F56C11.6, Cele\F13H6.3, Cele\Y71H2AM.13, Cele\T28C12.5, Cele\K11G9.3, Cele\F07C4.12, Cele\T02B5.3, Cele\F15A8.6, Cele\C52A10.1, Cele\K11G9.1, Cele\T28C12.4, Cele\ace-1, Cele\T07H6.1, Cele\K07C11.4, Cele\R173.3, Cele\C17H12.4, Cele\B0238.1, Cele\ace-2" "Xtro\nlgn3, Xtro\LOC100494782, Xtro\ces3, Xtro\nlgn4x, Xtro\nlgn2, Xtro\ces2, Xtro\cel" "Mmus\Nlgn3, Mmus\Ces1g, Mmus\Ache, Mmus\Ces1e, Mmus\Ces3b, Mmus\Ces2b, Mmus\Ces5a, Mmus\Ces1h, Mmus\Ces1d, Mmus\Ces2a, Mmus\Ces1c, Mmus\Ces2f, Mmus\Ces2c, Mmus\Ces2e, Mmus\Ces2h, Mmus\Nlgn2, Mmus\Nlgn1, Mmus\Cel, Mmus\Ces3a, Mmus\Ces1f, Mmus\Ces4a, Mmus\Ces2g, Mmus\Ces1b" "Hsap\CEL, Hsap\NLGN1, Hsap\CES5A, Hsap\CES3, Hsap\NLGN4Y, Hsap\NLGN4X, Hsap\NLGN2, Hsap\CES4A, Hsap\CES1, Hsap\ACHE, Hsap\CES2, Hsap\NLGN3" viable FBgn0030538 betaNACtes1 "Nascent-associated complex beta-subunit-like, testis 1" http://flybase.org/reports/FBgn0030538 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "betaNACtes1, CG13402" IPR002715:Nascent polypeptide-associated complex NAC domain CG13402 11-Aug-17 DroID_v2017_08 "Drer\tab2, Drer\btf3, Drer\btf3l4, Drer\tab3" "Scer\WWM1, Scer\BTT1, Scer\YML020W, Scer\EGD1" Cele\icd-1 "Xtro\btf3l4, Xtro\btf3" "Mmus\Btf3, Mmus\Tab3, Mmus\Tab2, Mmus\Btf3l4" "Hsap\TAB2, Hsap\BTF3, Hsap\BTF3L4, Hsap\TAB3" viable FBgn0000151 awu augenwulst http://flybase.org/reports/FBgn0000151 - gene - - - awu - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,good" eye FBgn0060822 l(3)S052111b lethal (3) S052111b http://flybase.org/reports/FBgn0060822 gene - - - "0521/11, l(3)S052111b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0015281 Picrotoxin-resistant Picrotoxin-resistant http://flybase.org/reports/FBgn0015281 - gene - - - "PR9, PR38, Picrotoxin-resistant" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265530 CR44380 - http://flybase.org/reports/FBgn0265530 non_protein_coding_gene - - - CR44380 - CR44380 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263551 mir-4939 mir-4939 stem loop http://flybase.org/reports/FBgn0263551 miRNA_gene - - - "mir-4939, dme-mir-4939, CR43536" - CR43536 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052598 betaNACtes6 "Nascent-associated complex beta-subunit-like, testis 6" http://flybase.org/reports/FBgn0052598 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32598, betaNACtes6" IPR002715:Nascent polypeptide-associated complex NAC domain CG32598 11-Aug-17 DroID_v2017_08 "Drer\tab2, Drer\btf3l4, Drer\tab3, Drer\btf3" "Scer\BTT1, Scer\EGD1, Scer\YML020W, Scer\WWM1" Cele\icd-1 "Xtro\btf3l4, Xtro\btf3" "Mmus\Btf3l4, Mmus\Tab2, Mmus\Btf3, Mmus\Tab3" "Hsap\TAB2, Hsap\TAB3, Hsap\BTF3, Hsap\BTF3L4" FBgn0086028 snoRNA:Me28S-G2173 - http://flybase.org/reports/FBgn0086028 snoRNA_gene - - - "snoRNA:Me28S-G2173, Me28S-Gm2173, Me28S-G2173, CR34657" - CR34657 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002451 l(3)SG4 lethal (3) SG4 http://flybase.org/reports/FBgn0002451 - gene - - - l(3)SG4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035359 CG1143 - http://flybase.org/reports/FBgn0035359 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG1143 - CG1143 11-Aug-17 DroID_v2017_08 - - "Cele\W05F2.6, Cele\phf-33" - - - viable DRSC08188 E 0.715459501 0.608115738 1.761592663 -0.093606337 0.257778352 -0.214001712 FBgn0061160 l(1)7Dp lethal (1) 7Dp http://flybase.org/reports/FBgn0061160 gene - - - l(1)7Dp - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035827 Srp9 Signal recognition particle protein 9 http://flybase.org/reports/FBgn0035827 protein_coding_gene "7S RNA binding ; GO:0008312 | inferred from electronic annotation with InterPro:IPR008832, InterPro:IPR009018 signal recognition particle binding ; GO:0005047 | inferred from biological aspect of ancestor with PANTHER:PTN000303113" "negative regulation of translational elongation ; GO:0045900 | inferred from electronic annotation with InterPro:IPR008832 SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616 | inferred from biological aspect of ancestor with PANTHER:PTN000303113" "signal recognition particle receptor complex ; GO:0005785 | inferred from biological aspect of ancestor with PANTHER:PTN000303113 signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from biological aspect of ancestor with PANTHER:PTN000303113" "CG8268, Srp9" "IPR008832:Signal recognition particle, SRP9 subunit, IPR009018:Signal recognition particle, SRP9/SRP14 subunit" CG8268 11-Aug-17 DroID_v2017_08 Drer\srp9 Scer\SRP21 Cele\ZK512.4 - Mmus\Srp9 Hsap\SRP9 "viable,visible" mesothoracic tergum FBgn0051997 CG31997 - http://flybase.org/reports/FBgn0051997 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytosol ; GO:0005829 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "BEST:GH25016, BcDNA:RE42475, CG31997" IPR029277:Single domain Von Willebrand factor type C domain CG31997 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0012028 tRNA:Tyr-GTA-1-4 transfer RNA:Tyrosine-GTA 1-4 http://flybase.org/reports/FBgn0012028 "FBgn0003849, FBgn0012014, FBgn0051387, FBgn0060001" tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "Tyr-tRNA, tRNA-Tyr, 85Ae, tRNA[Tyr][[1gamma]], AE002708.trna61-TyrGTA, tRNA:Y, tRNA:Y:GTA:AE002708-e, CR31387, tRNA:tyr1:85Ae, tRNA[Tyr], chr3R.trna67-TyrGTA, tRNA-Tyr-GTA-1-4, tRNA:Tyr-GTA-1-4, tRNA:Y1:85Ae, UAC" - CR31387 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051646 DIP-theta Dpr-interacting protein theta http://flybase.org/reports/FBgn0051646 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG14009, CT33566, CG14008, CG31646, 31646, DIP-theta" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain" CG31646 11-Aug-17 DroID_v2017_08 "Drer\f11r.2, Drer\cxadr, Drer\si:zfos-1011f11.1, Drer\mxra8a, Drer\jam2a, Drer\zgc:153073, Drer\sdk1a, Drer\kirrelb, Drer\negr1, Drer\esamb, Drer\si:ch211-215e19.3, Drer\pigrl4.2, Drer\kirrel3l, Drer\paplna, Drer\vsig8a, Drer\vsig8b, Drer\kirrel3b, Drer\kirrela, Drer\si:dkey-65b12.12, Drer\igsf9a, Drer\jam3a, Drer\lrit1a, Drer\lrit3b, Drer\lrit1b, Drer\zgc:110372, Drer\si:dkey-250k15.10, Drer\lrit3a, Drer\cxcr3.1, Drer\itgb4, Drer\esama, Drer\gpa33, Drer\igsf9bb, Drer\mxra8b, Drer\igsf11, Drer\jam3b, Drer\kirrel3a, Drer\jam2b, Drer\opcml, Drer\dscama, Drer\f11r.1, Drer\si:ch211-9d9.7, Drer\ncam1b, Drer\LOC100151468, Drer\si:ch1073-459j12.1, Drer\ntm, Drer\ush2a, Drer\sdk1b" - Cele\rig-5 "Xtro\lrit3, Xtro\negr1, Xtro\opcml, Xtro\kirrel2, Xtro\igsf9b, Xtro\lsamp, Xtro\papln, Xtro\ntm" "Mmus\Esam, Mmus\Jam3, Mmus\Igsf5, Mmus\Jam2, Mmus\Igsf9b, Mmus\Vsir, Mmus\Lrit1, Mmus\Lsamp, Mmus\Opcml, Mmus\Ntm, Mmus\Gpa33, Mmus\Vsig8, Mmus\F11r, Mmus\Igsf11, Mmus\Negr1, Mmus\Vsig1, Mmus\Kirrel, Mmus\Kirrel3, Mmus\Mxra8, Mmus\Lrit3, Mmus\Vsig2, Mmus\Iglon5, Mmus\Clmp, Mmus\Cxadr, Mmus\Hepacam2, Mmus\Gm1123, Mmus\Kirrel2, Mmus\Sdk1, Mmus\Papln, Mmus\Ptprq" "Hsap\LRIT3, Hsap\ESAM, Hsap\CLMP, Hsap\IGSF9B, Hsap\OPCML, Hsap\VSIG1, Hsap\IGSF11, Hsap\NTM, Hsap\LSAMP, Hsap\JAM2, Hsap\KIRREL3, Hsap\SDK1, Hsap\IGSF5, Hsap\GPA33, Hsap\JAM3, Hsap\NEGR1, Hsap\VSIG2, Hsap\MXRA8, Hsap\IGLON5, Hsap\C10orf54, Hsap\CXADR, Hsap\VSIG8, Hsap\KIRREL2, Hsap\C1orf204, Hsap\KIRREL, Hsap\USH2A, Hsap\PAPLN, Hsap\F11R, Hsap\LRIT1" FBgn0044343 springer\gag springer element gag http://flybase.org/reports/FBgn0044343 transposable_element_gene - - - "ORF1, springer\gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014095 anon-3Ab anon-3Ab http://flybase.org/reports/FBgn0014095 - gene - - - anon-3Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage--pupal stage FBgn0031585 CG2955 - http://flybase.org/reports/FBgn0031585 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR027328 - - "anon-WO0140519.175, CG2955" "IPR001715:Calponin homology domain, IPR027328:Microtubule-associated protein RP/EB" CG2955 11-Aug-17 DroID_v2017_08 "Drer\mapre3a, Drer\mapre3b, Drer\mapre1b, Drer\mapre2, Drer\mapre1a" Scer\BIM1 "Cele\ebp-2, Cele\ebp-3, Cele\ebp-1" Xtro\mapre1 "Mmus\Mapre1, Mmus\Mapre3, Mmus\Mapre2" "Hsap\MAPRE1, Hsap\MAPRE3, Hsap\MAPRE2" viable FBgn0034175 ste24b ste24b prenyl protease type I http://flybase.org/reports/FBgn0034175 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000012712 spermatogenesis ; GO:0007283 | inferred from mutant phenotype CAAX-box protein processing ; GO:0071586 | inferred from biological aspect of ancestor with PANTHER:PTN000012712 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000012714 "ste24b, CG9001, Dmel\Ste24, Dmel\Ste24b" "IPR001915:Peptidase M48, IPR027057:CAAX prenyl protease 1, IPR032456:CAAX prenyl protease 1, N-terminal" CG9001 11-Aug-17 DroID_v2017_08 Drer\zmpste24 Scer\STE24 Cele\fce-1 Xtro\zmpste24 Mmus\Zmpste24 Hsap\ZMPSTE24 viable DRSC24340 K 0.196038561 0.488795655 0.131569967 -0.24814698 -0.0485922 -1.511281091 FBgn0002766 mit(1)17 mitotic 17 http://flybase.org/reports/FBgn0002766 - gene - - - mit(1)17 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263072 CG43347 - http://flybase.org/reports/FBgn0263072 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000003381" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR027775" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 "CG43347, CG9817, BcDNA:RH11383, CG15295" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR027775:C2H2- zinc finger protein family subset, IPR013087:Zinc finger C2H2-type" CG43347 11-Aug-17 DroID_v2017_08 "Drer\znf131, Drer\zgc:171929, Drer\prdm5, Drer\ovol1, Drer\si:dkey-17e16.13" Scer\RPN4 "Cele\Y5F2A.4, Cele\lin-48, Cele\ztf-2" Xtro\prdm5 "Mmus\Ovol3, Mmus\Ovol1, Mmus\Rest, Mmus\Zfp131, Mmus\Ovol2, Mmus\Prdm5, Mmus\Zfp770" "Hsap\ZNF131, Hsap\ZNF770, Hsap\OVOL1, Hsap\OVOL3, Hsap\PRDM5, Hsap\REST, Hsap\OVOL2" FBgn0265298 SC35 SR family splicing factor SC35 http://flybase.org/reports/FBgn0265298 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Trn-SR mRNA binding ; GO:0003729 | inferred from direct assay "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype regulation of mRNA 3'-end processing ; GO:0031440 | inferred from mutant phenotype regulation of transcriptional start site selection at RNA polymerase II promoter ; GO:0001178 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay omega speckle ; GO:0035062 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nuclear speck ; GO:0016607 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay "SC35, sc35, SC-35, CG5442, dSC35, CG5542, cg5442, Sc35, anon-EST:Posey284, CG15494" IPR000504:RNA recognition motif domain CG5442 11-Aug-17 DroID_v2017_08 "Drer\LOC103909923, Drer\cirbpb, Drer\rbm38, Drer\srsf2a, Drer\srsf10a, Drer\rbmx, Drer\rbm24b, Drer\cirbpa, Drer\srsf2b, Drer\rbm24a" Scer\NSR1 "Cele\R09B3.2, Cele\rsp-6, Cele\R06C1.4, Cele\rsp-4, Cele\rnp-5, Cele\R09B3.3, Cele\sup-12" "Xtro\rbm24, Xtro\cirbp, Xtro\srsf2, Xtro\srsf12, Xtro\rbm38, Xtro\rbmx, Xtro\rnps1, Xtro\srsf10" "Mmus\Gm21708, Mmus\4930595M18Rik, Mmus\Rbmxl1, Mmus\Rbmxl2, Mmus\Gm10256, Mmus\Srsf10, Mmus\Rbmx, Mmus\Rnps1, Mmus\Rbm38, Mmus\Rbm24, Mmus\Rbmy, Mmus\Gm4064, Mmus\Rbm3, Mmus\Srsf2, Mmus\Gm21677, Mmus\Gm21693, Mmus\Cirbp, Mmus\Gm3376" "Hsap\SRSF12, Hsap\SRSF2, Hsap\RBMXL1, Hsap\SRSF8, Hsap\RBMY1B, Hsap\SRSF10, Hsap\RBMXL2, Hsap\RBMY1A1, Hsap\RBM3, Hsap\RNPS1, Hsap\RBMY1J, Hsap\RBMY1E, Hsap\RBM24, Hsap\CIRBP, Hsap\RBMX, Hsap\RBM38, Hsap\RBMY1D, Hsap\RBMY1F, Hsap\RBMXL3" FBgn0038655 CG14297 - http://flybase.org/reports/FBgn0038655 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with SGD:S000006277 protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000006277 protein dephosphorylation ; GO:0006470 | non-traceable author statement nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000006277 cytoplasm ; GO:0005737 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000006277 "LMW-PTP, CG14297" "IPR023485:Phosphotyrosine protein phosphatase I superfamily, IPR017867:Protein-tyrosine phosphatase, low molecular weight" CG14297 11-Aug-17 DroID_v2017_08 - Scer\LTP1 Cele\Y94H6A.7 Xtro\acp1 Mmus\Acp1 Hsap\ACP1 FBgn0083265 E(smoDN)474 Enhancer of smoDN 474 http://flybase.org/reports/FBgn0083265 gene - - - E(smoDN)474 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022022 l(2)k09005 lethal (2) k09005 http://flybase.org/reports/FBgn0022022 - gene - - - l(2)k09005 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051446 CG31446 - http://flybase.org/reports/FBgn0051446 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE40372, CG31446" IPR012674:Calycin CG31446 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028944 Semp1 Seminal metalloprotease-1 http://flybase.org/reports/FBgn0028944 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity endopeptidase activity ; GO:0004175 | inferred from mutant phenotype protein processing ; GO:0016485 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cell migration ; GO:0016477 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG11864, BACR44L22.8, BG:BACR44L22.8, Semp1, semp1" "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG11864 11-Aug-17 DroID_v2017_08 "Drer\he1b, Drer\he2, Drer\npsn, Drer\LOC797085, Drer\mep1a.1, Drer\c6ast4, Drer\tll1, Drer\bmp1b, Drer\tnfaip6, Drer\LOC100003133, Drer\c6ast1, Drer\mep1b, Drer\he1a, Drer\c6ast3, Drer\mep1a.2, Drer\bmp1a, Drer\si:ch73-40a17.3, Drer\npsnl" - "Cele\nas-5, Cele\nas-12, Cele\nas-15, Cele\nas-7, Cele\nas-8, Cele\nas-1, Cele\Y19D10A.6, Cele\nas-14, Cele\nas-2, Cele\nas-4, Cele\nas-13, Cele\ZC116.3, Cele\nas-39, Cele\nas-6" "Xtro\cubn, Xtro\mep1a, Xtro\LOC100489456, Xtro\tll2, Xtro\mep1b, Xtro\LOC100492324, Xtro\tnfaip6, Xtro\uvs.2, Xtro\bmp1, Xtro\accs, Xtro\tll1" "Mmus\Tll2, Mmus\Bmp1, Mmus\Astl, Mmus\Cubn, Mmus\Mep1b, Mmus\Tnfaip6, Mmus\Adgrg6, Mmus\Tll1, Mmus\Mep1a" "Hsap\MEP1A, Hsap\ASTL, Hsap\CUBN, Hsap\TLL2, Hsap\TLL1, Hsap\ADGRG6, Hsap\BMP1, Hsap\MEP1B, Hsap\TNFAIP6" viable FBgn0065496 l(2)SH1218 lethal (2) SH1218 http://flybase.org/reports/FBgn0065496 gene - - - "l(2)SH1218, l(2)SH2 1218" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034713 CG11291 - http://flybase.org/reports/FBgn0034713 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with HGNC:30259 phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:30259 dephosphorylation ; GO:0016311 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000445812 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:30259 "CG11291, Phos11291, 22026920" "IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG11291 11-Aug-17 DroID_v2017_08 "Drer\pdxp, Drer\pgp" Scer\PHO13 "Cele\C45E5.1, Cele\C53A3.2, Cele\F44E7.2, Cele\K02D10.1, Cele\K09H11.7" - "Mmus\Pgp, Mmus\Pdxp" "Hsap\PGP, Hsap\PDXP" viable FBgn0032849 mRpS18B mitochondrial ribosomal protein S18B http://flybase.org/reports/FBgn0032849 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82918 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y676 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:P82918 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y676 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y676 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82918 "CG10757, 38B.17, MRP-S18-(2), mRpS18b, mRpS18B" IPR001648:Ribosomal protein S18 CG10757 11-Aug-17 DroID_v2017_08 Drer\mrps18b - Cele\mrps-18B Xtro\mrps18b "Mmus\Mrps18a, Mmus\Mrps18b" "Hsap\MRPS18B, Hsap\MRPS18A" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0001429 l(1)6Fb lethal (1) 6Fb http://flybase.org/reports/FBgn0001429 - gene - - - l(1)6Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051568 tRNA:Ala-AGC-2-6 transfer RNA:Alanine-AGC 2-6 http://flybase.org/reports/FBgn0051568 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna45-AlaAGC, tRNA:A:AGC:AE002708-i, CR31568, tRNA[[Ala]], chr3R.trna51-AlaAGC, tRNA-Ala-AGC-2-6, tRNA:Ala-AGC-2-6, tRNA:CR31568, GCU" - CR31568 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265713 CR44520 - http://flybase.org/reports/FBgn0265713 non_protein_coding_gene - - - CR44520 - CR44520 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264640 cystic-lumens cystic lumens http://flybase.org/reports/FBgn0264640 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - cystic-lumens - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0030049 Trf4-1 Topoisomerase related function 4-1 http://flybase.org/reports/FBgn0030049 protein_coding_gene polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from direct assay DNA-directed DNA polymerase activity ; GO:0003887 | non-traceable author statement ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process ; GO:0043630 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | non-traceable author statement - "AAF46390, Trf4-1, CG11265, Trf4, DmTRF4-1, dTrf4-1" "IPR002058:PAP/25A-associated, IPR002934:Polymerase, nucleotidyl transferase domain" CG11265 11-Aug-17 DroID_v2017_08 "Drer\papd5, Drer\papd7" "Scer\TRF5, Scer\PAP2" Cele\gld-4 Xtro\papd5 "Mmus\Papd7, Mmus\Papd5" "Hsap\PAPD7, Hsap\PAPD5" "visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,viable,fertile" "eye,wing,head | pupal stage,trichogen cell" FBgn0000132 Ars-region10 Autonomous replicating sequence region 10 http://flybase.org/reports/FBgn0000132 - region - - - "HHa240, Ars-region10, Ars10" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015558 tty tweety http://flybase.org/reports/FBgn0015558 - protein_coding_gene chloride channel activity ; GO:0005254 | inferred from sequence or structural similarity with UniProtKB:Q9C0H2 chloride channel activity ; GO:0005254 | inferred from sequence or structural similarity with HGNC:22222 chloride transport ; GO:0006821 | inferred from sequence or structural similarity with HGNC:22222 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q9C0H2 "CG1693, twe, tty, TTYH1" "IPR006990:Tweety, IPR011989:Armadillo-like helical" CG1693 11-Aug-17 DroID_v2017_08 "Drer\ttyh3a, Drer\ttyh3b, Drer\ttyh2, Drer\ttyh1, Drer\ttyh2l" - Cele\ttyh-1 "Xtro\ttyh2, Xtro\ttyh1, Xtro\ttyh3" "Mmus\Ttyh2, Mmus\Ttyh3, Mmus\Ttyh1" "Hsap\TTYH2, Hsap\TTYH1, Hsap\TTYH3" viable FBgn0038947 Sar1 Secretion-associated Ras-related 1 http://flybase.org/reports/FBgn0038947 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006687, InterPro:IPR006689 scaffold protein binding ; GO:0097110 | inferred from physical interaction with Sec16 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTP binding ; GO:0005525 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000006139" positive regulation of protein exit from endoplasmic reticulum ; GO:0070863 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype regulation of COPII vesicle coating ; GO:0003400 | inferred from sequence or structural similarity with SGD:S000006139 embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype positive regulation of cuticle pigmentation ; GO:0048081 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype protein targeting to plasma membrane ; GO:0072661 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay COPII vesicle coat ; GO:0030127 | inferred from sequence or structural similarity with SGD:S000006139 endoplasmic reticulum exit site ; GO:0070971 | inferred from direct assay "Sar1, Dm Sar1, NP_732719, dsar1, CG7073, l(3)05712, clone 1.48, 5712, anon-EST:Liang-1.48, bro5, sar1, dar3, SAR1, Q95SY7" "IPR005225:Small GTP-binding protein domain, IPR006687:Small GTPase superfamily, SAR1-type, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7073 11-Aug-17 DroID_v2017_08 "Drer\ppa2, Drer\sar1aa, Drer\ppa1a, Drer\sar1b, Drer\sar1ab, Drer\ppa1b" Scer\SAR1 "Cele\sar-1, Cele\pyp-1" "Xtro\sar1b, Xtro\ppa1, Xtro\sar1a, Xtro\ppa2" "Mmus\Sar1a, Mmus\Sar1b, Mmus\Ppa1, Mmus\Ppa2" "Hsap\SAR1B, Hsap\PPA2, Hsap\SAR1A, Hsap\PPA1" "lethal,recessive,neuroanatomy defective,cell autonomous,somatic clone,female sterile,germline clone,small body,lethal - all die before end of larval stage,some die during larval stage" "embryonic pericardial cell,cardioblast,dendrite & dendritic arborising neuron,dendrite & dendritic arborising neuron | somatic clone | cell autonomous,dendrite & dorsal multidendritic neuron ddaC | somatic clone | cell autonomous,Golgi apparatus & dendritic arborising neuron | somatic clone | cell autonomous,embryonic/first instar larval cuticle,endoplasmic reticulum | late embryonic stage,embryonic/larval epidermis,sarcomereMef2.PR" FBgn0265710 CR44517 - http://flybase.org/reports/FBgn0265710 non_protein_coding_gene - - - "lincRNA.969, CR44517" - CR44517 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019949 Cdk9 Cyclin-dependent kinase 9 http://flybase.org/reports/FBgn0019949 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | traceable author statement cyclin binding ; GO:0030332 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from direct assay cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity with SGD:S000001622" "protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000001622 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype phosphorylation of RNA polymerase II C-terminal domain ; GO:0070816 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from direct assay cell adhesion ; GO:0007155 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from direct assay transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000623455" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay ELL-EAF complex ; GO:0032783 | inferred from physical interaction with Su(Tpl) polytene chromosome ; GO:0005700 | inferred from direct assay cyclin/CDK positive transcription elongation factor complex ; GO:0008024 | traceable author statement "P-TEFb, CDK9, cdk9, CG5179, P-TEF, PTefb, Cdk9" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG5179 11-Aug-17 DroID_v2017_08 Drer\cdk9 "Scer\SGV1, Scer\CTK1" "Cele\cdk-9, Cele\cdk-12" "Xtro\cdk12, Xtro\cdk9, Xtro\cdk13" "Mmus\Cdk12, Mmus\Cdk9, Mmus\Cdk13" "Hsap\CDK13, Hsap\CDK12, Hsap\CDK9" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC04601 IEK -0.546952694 4.937404282 1.812523158 2.3613096 1.620861677 2.622750373 FBgn0053281 CG33281 - http://flybase.org/reports/FBgn0053281 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "CG15407, CG33281" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG33281 11-Aug-17 DroID_v2017_08 "Drer\slc2a13b, Drer\slc2a6, Drer\slc2a12, Drer\LOC101882338, Drer\slc2a8, Drer\slc2a10" "Scer\HXT14, Scer\SNF3, Scer\VBA4, Scer\ENB1, Scer\MPH3, Scer\YMR279C, Scer\STL1, Scer\HXT2, Scer\ITR1, Scer\GAL2, Scer\MAL31, Scer\HXT1, Scer\YDR387C, Scer\HXT17, Scer\HXT3, Scer\VBA5, Scer\VBA2, Scer\HXT7, Scer\GEX1, Scer\VBA3, Scer\RGT2, Scer\GEX2, Scer\HXT9, Scer\YDL199C, Scer\ATR1, Scer\ITR2, Scer\HXT6, Scer\YFL040W, Scer\MAL11, Scer\SGE1, Scer\VBA1, Scer\HXT5, Scer\HXT16, Scer\HXT11, Scer\MPH2, Scer\HXT8, Scer\AZR1, Scer\HXT4, Scer\HXT15, Scer\HXT10, Scer\HXT13" "Cele\K09C4.4, Cele\F11D5.5, Cele\slcf-2, Cele\hmit-1.1, Cele\K09C4.2" "Xtro\slc2a10, Xtro\slc2a12, Xtro\slc2a6, Xtro\slc2a8" "Mmus\Slc2a13, Mmus\Slc2a6, Mmus\Slc2a8, Mmus\Slc2a12, Mmus\Slc2a10" "Hsap\SLC2A10, Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SLC2A8, Hsap\SLC2A12" viable FBgn0065560 l(2)SH0996 lethal (2) SH0996 http://flybase.org/reports/FBgn0065560 gene - - - "l(2)SH0996, l(2)SH2 0996" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065745 l(2)SH0517 lethal (2) SH0517 http://flybase.org/reports/FBgn0065745 gene - - - "l(2)SH0517, l(2)SH2 0517" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266856 CR45317 - http://flybase.org/reports/FBgn0266856 non_protein_coding_gene - - - "CR45317, lincRNA.321" - CR45317 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012016 tRNA:Tyr-GTA-1-3 transfer RNA:Tyrosine-GTA 1-3 http://flybase.org/reports/FBgn0012016 "FBgn0003842, FBgn0012014, FBgn0051987, FBgn0060006" tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "tRNA-Tyr, tRNA[Tyr], Y22Fa, tRNA[Tyr][[1gamma]], AE002638.trna13-TyrGTA, tRNA:Y, tRNA:Y:GTA:AE002638-b, CR31987, tRNA:tyr1:22Fa, chr2L.trna6-TyrGTA, tRNA-Tyr-GTA-1-3, tRNA:Tyr-GTA-1-3, tRNA:Y1:22Fa, UAC" - CR31987 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,male sterile,female fertile" FBgn0051940 tRNA:Gln-CTG-3-1 transfer RNA:Glutamine-CTG 3-1 http://flybase.org/reports/FBgn0051940 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002638.trna5-GlnCTG, tRNA:Q:CTG:AE002638-b, CR31940, chr2L.trna38-GlnCTG, tRNA:Gln-CTG-3-1, tRNA:CR31940, tRNA-Gln-CTG-3-1, CAG" - CR31940 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021842 l(2)k14817 lethal (2) k14817 http://flybase.org/reports/FBgn0021842 - gene - - - l(2)k14817 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051577 tRNA:Ala-AGC-1-1 transfer RNA:Alanine-AGC 1-1 http://flybase.org/reports/FBgn0051577 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna16-AlaAGC, tRNA:A:AGC:AE002708-d, CR31577, tRNA[[Ala]], chr3R.trna22-AlaAGC, tRNA-Ala-AGC-1-1, tRNA:Ala-AGC-1-1, tRNA:CR31577, GCU" - CR31577 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032476 CG5439 - http://flybase.org/reports/FBgn0032476 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5439 "IPR001683:Phox homologous domain, IPR004012:RUN domain" CG5439 11-Aug-17 DroID_v2017_08 "Drer\rubcn, Drer\snx29, Drer\rundc3b, Drer\plekhf2, Drer\snx25, Drer\rufy2, Drer\kif16ba, Drer\rufy1, Drer\rundc3aa, Drer\rundc3ab, Drer\plekhm2, Drer\plekhf1" - "Cele\aka-1, Cele\ZK632.12" "Xtro\snx29, Xtro\kif16b, Xtro\rundc3b, Xtro\rundc3a, Xtro\rufy1, Xtro\rufy2, Xtro\rufy3" "Mmus\Rufy2, Mmus\Kif16b, Mmus\Snx29, Mmus\Rundc3a, Mmus\Rundc3b, Mmus\Rufy3, Mmus\Snx15, Mmus\Snx20, Mmus\Rps6kc1, Mmus\Sgk3, Mmus\Rubcn, Mmus\Plekhf1, Mmus\Snx25, Mmus\Rufy1, Mmus\Plekhm2, Mmus\Plekhf2" "Hsap\RUFY3, Hsap\SGK3, Hsap\SNX25, Hsap\RUFY1, Hsap\RUBCN, Hsap\PLEKHF1, Hsap\PLEKHM2, Hsap\PLEKHF2, Hsap\SNX29, Hsap\SNX16, Hsap\RUNDC3A, Hsap\RUNDC3B, Hsap\RPS6KC1, Hsap\SNX15, Hsap\RUFY2" viable FBgn0060428 l(3)S126110b lethal (3) S126110b http://flybase.org/reports/FBgn0060428 gene - - - "1261/10, l(3)S126110b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004953 1688-11EF 1.688 satellite-related 11EF http://flybase.org/reports/FBgn0004953 - repeat_region - - - "1.688, 1688-11EF" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035014 CG13581 - http://flybase.org/reports/FBgn0035014 protein_coding_gene - - - "BcDNA:AT03240, CG13581" - CG13581 11-Aug-17 DroID_v2017_08 - - - - Mmus\Gm9047 - viable FBgn0005476 l(1)ts1064 lethal (1) ts1064 http://flybase.org/reports/FBgn0005476 - gene - - - l(1)ts1064 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0029669 CG13021 - http://flybase.org/reports/FBgn0029669 protein_coding_gene - - - "BcDNA:AT30881, CG13021" - CG13021 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065878 l(2)SH0239 lethal (2) SH0239 http://flybase.org/reports/FBgn0065878 gene - - - "l(2)SH0239, l(2)SH2 0239" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266917 Sf3a1 Splicing factor 3a subunit 1 http://flybase.org/reports/FBgn0266917 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000393333 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:10765 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000003739 spermatogenesis ; GO:0007283 | inferred from mutant phenotype mRNA 3'-splice site recognition ; GO:0000389 | inferred from biological aspect of ancestor with PANTHER:PTN000393333" precatalytic spliceosome ; GO:0071011 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000003739 U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000393333 nucleus ; GO:0005634 | inferred by curator from GO:0000381 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000393333 "Sf3a1, SF3a120, SF3a1, l(3)SH146, l(2)SH3 146, CG16941, sf3a1, SF3A1" "IPR000061:SWAP/Surp, IPR000626:Ubiquitin domain, IPR019956:Ubiquitin, IPR022030:Splicing factor 3A subunit 1, IPR029071:Ubiquitin-related domain" CG16941 11-Aug-17 DroID_v2017_08 Drer\sf3a1 Scer\PRP21 Cele\prp-21 Xtro\sf3a1 Mmus\Sf3a1 Hsap\SF3A1 DRSC15166 EK -0.43346835 0.960820442 -1.434809785 -2.21796498 -1.860759951 -0.634141523 FBgn0262174 mir-993 mir-993 stem loop http://flybase.org/reports/FBgn0262174 miRNA_gene - - - "dme-mir-993, mir-993, miR-993, CR42881, dme-miR-993" - CR42881 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0261510 cos::Khc - http://flybase.org/reports/FBgn0261510 engineered_fusion_gene - - - "kinco, cos::Khc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053423 5SrRNA:CR33423 5SrRNA:CR33423 http://flybase.org/reports/FBgn0053423 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33423, 5SrRNA:CR33423" - CR33423 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085354 CG34325 - http://flybase.org/reports/FBgn0085354 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 - - "CG34325, CG18358" "IPR001781:Zinc finger, LIM-type" CG34325 11-Aug-17 DroID_v2017_08 "Drer\fhl3b, Drer\pdlim3a, Drer\pxna, Drer\fhl3a, Drer\pdlim5b, Drer\pdlim4, Drer\pxnb, Drer\pdlim2, Drer\pdlim7, Drer\pdlim3b, Drer\si:rp71-15d4.1, Drer\pdlim5a, Drer\pdlim1, Drer\zyx" "Scer\LRG1, Scer\PXL1" "Cele\alp-1, Cele\Y1A5A.1" "Xtro\pxn, Xtro\tgfb1i1, Xtro\fhl5, Xtro\pdlim7, Xtro\pdlim5, Xtro\fhl2, Xtro\pdlim1, Xtro\fhl3, Xtro\pdlim4, Xtro\pdlim3" "Mmus\Pxn, Mmus\Ldb3, Mmus\Pdlim7, Mmus\Pdlim4, Mmus\Pdlim1, Mmus\Pdlim2, Mmus\Tgfb1i1, Mmus\Fhl5, Mmus\Lpxn, Mmus\Fhl4, Mmus\Fhl1, Mmus\Pdlim5, Mmus\Pdlim3, Mmus\Fhl3, Mmus\Fhl2" "Hsap\PDLIM4, Hsap\PDLIM5, Hsap\TGFB1I1, Hsap\PDLIM7, Hsap\FHL5, Hsap\FHL2, Hsap\LDB3, Hsap\FHL1, Hsap\PDLIM3, Hsap\PDLIM2, Hsap\PXN, Hsap\PDLIM1, Hsap\FHL3, Hsap\LPXN" "viable,fertile" FBgn0065082 snmRNA:782 small non-messenger RNA 782 http://flybase.org/reports/FBgn0065082 non_protein_coding_gene - - - "Dm-782, snmRNA:782" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037239 Sfxn1-3 Sideroflexin 1/3 http://flybase.org/reports/FBgn0037239 protein_coding_gene ion transmembrane transporter activity ; GO:0015075 | inferred from electronic annotation with InterPro:IPR004686 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004686 ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR004686 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR004686 "anon-EST:Posey55, CG11739, Sfxn1-3" IPR004686:Tricarboxylate/iron carrier CG11739 11-Aug-17 DroID_v2017_08 "Drer\sfxn4, Drer\sfxn5a, Drer\sfxn3, Drer\sfxn5b, Drer\sfxn1" Scer\FSF1 "Cele\sfxn-1.3, Cele\sfxn-1.2, Cele\sfxn-1.1, Cele\sfxn-1.4, Cele\sfxn-5, Cele\sfxn-1.5" "Xtro\sfxn3, Xtro\sfxn1, Xtro\sfxn2, Xtro\sfxn5" "Mmus\Sfxn5, Mmus\Sfxn3, Mmus\Sfxn1, Mmus\Sfxn4, Mmus\Sfxn2" "Hsap\SFXN5, Hsap\SFXN2, Hsap\SFXN3, Hsap\SFXN1, Hsap\SFXN4" "viable,fertile" FBgn0086322 JV212 - http://flybase.org/reports/FBgn0086322 gene - - - JV212 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0032682 grnd grindelwald http://flybase.org/reports/FBgn0032682 protein_coding_gene tumor necrosis factor-activated receptor activity ; GO:0005031 | inferred from direct assay tumor necrosis factor-mediated signaling pathway ; GO:0033209 | inferred from genetic interaction with egr positive regulation of apoptotic signaling pathway ; GO:2001235 | inferred from genetic interaction with egr positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "grnd, CG10176, grindelwald" - CG10176 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265395 Lsd-1::Lsd-2 - http://flybase.org/reports/FBgn0265395 engineered_fusion_gene - - - Lsd-1::Lsd-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036015 CG3088 - http://flybase.org/reports/FBgn0036015 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SPH188, CG3088" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG3088 11-Aug-17 DroID_v2017_08 Drer\masp2 - - - "Mmus\C1s1, Mmus\C1s2, Mmus\Cela1" "Hsap\F9, Hsap\C1S, Hsap\PROC" "partially lethal - majority die,some die during pupal stage" FBgn0052786 CG32786 - http://flybase.org/reports/FBgn0052786 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32786 - CG32786 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028095 l(3)S074706 lethal (3) S074706 http://flybase.org/reports/FBgn0028095 gene - - - "0747/06, l(3)S074706" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086613 Ino80 INO80 complex subunit http://flybase.org/reports/FBgn0086613 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q9ULG1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8ST83 DNA helicase activity ; GO:0003678 | inferred from sequence or structural similarity with UniProtKB:Q9ULG1 ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with UniProtKB:Q9ULG1 regulatory region DNA binding ; GO:0000975 | inferred from direct assay "DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR031047 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype regulation of development, heterochronic ; GO:0040034 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from sequence or structural similarity with UniProtKB:Q9ULG1" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay Ino80 complex ; GO:0031011 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from direct assay "Ino80, CG31212, dINO80, CG3602, CG18491, CG14279, dIno80, INO80, psg25" "IPR001650:Helicase, C-terminal, IPR000330:SNF2-related, N-terminal domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR020838:DBINO domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031047:DNA helicase Ino80" CG31212 11-Aug-17 DroID_v2017_08 Drer\ino80 "Scer\INO80, Scer\SWR1" - Xtro\ino80 Mmus\Ino80 Hsap\INO80 FBgn0040216 fs(3)BA32 fs(3)BA32 http://flybase.org/reports/FBgn0040216 gene - - - fs(3)BA32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0260071 2L2269 - http://flybase.org/reports/FBgn0260071 gene - - - 2L2269 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0261806 CG42752 - http://flybase.org/reports/FBgn0261806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42752 - CG42752 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083015 snoRNA:Psi18S-920 snoRNA:Psi18S-920 http://flybase.org/reports/FBgn0083015 snoRNA_gene - - - "snoRNA:Psi18S-920, psi18S-920, Psi 18S-920, CR34641" - CR34641 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038343 Trissin Trissin http://flybase.org/reports/FBgn0038343 protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with TrissinR G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "Trissin, CG14871" - CG14871 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000240 bv brevis http://flybase.org/reports/FBgn0000240 - gene - - - "bs, bv" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable" macrochaeta FBgn0261933 SmD1 Small ribonucleoprotein particle protein SmD1 http://flybase.org/reports/FBgn0261933 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000596745 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:11158 "spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000596745 spliceosomal snRNP assembly ; GO:0000387 | inferred from biological aspect of ancestor with PANTHER:PTN000596745 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with UniProtKB:Q02260 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000003306" spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000003306 U4 snRNP ; GO:0005687 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 SMN-Sm protein complex ; GO:0034719 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 commitment complex ; GO:0000243 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 prespliceosome ; GO:0071010 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 pICln-Sm protein complex ; GO:0034715 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 spliceosomal tri-snRNP complex ; GO:0097526 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000596746 nucleus ; GO:0005634 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with UniProtKB:Q02260 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000003306 cytosol ; GO:0005829 | inferred from direct assay "snRNP-69D, CG10753, snRNP, BcDNA:RE39488, SmD1, smd1, snRNP69D, dD1, l(3)SH003, l(2)SH3 003, D1-Sm" "IPR027141:Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3, IPR034102:Small nuclear ribonucleoprotein D1, IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain" CG10753 11-Aug-17 DroID_v2017_08 "Drer\lsm10, Drer\snrpd1" Scer\SMD1 "Cele\snr-3, Cele\F40F8.11" "Xtro\snrpd1, Xtro\lsm10" "Mmus\Snrpd1, Mmus\Lsm10" "Hsap\SNRPD1, Hsap\LSM10" DRSC09800 E 1.116502588 1.107503146 2.276599588 0.309721651 -0.188340033 0.241763425 FBgn0026746 anon-25D26Ab anon-25D26Ab http://flybase.org/reports/FBgn0026746 - gene - - - "mst, anon-25D26Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036229 CG7248 - http://flybase.org/reports/FBgn0036229 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG7248 IPR002557:Chitin binding domain CG7248 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\C39D10.7, Cele\R02F2.4, Cele\F48E3.8, Cele\cpg-2, Cele\cpg-1" - - Hsap\MATN2 viable FBgn0052099 CG32099 - http://flybase.org/reports/FBgn0052099 protein_coding_gene magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR008278 holo-[acyl-carrier-protein] synthase activity ; GO:0008897 | inferred from biological aspect of ancestor with PANTHER:PTN000259224 lysine biosynthetic process via aminoadipic acid ; GO:0019878 | inferred from biological aspect of ancestor with PANTHER:PTN000259224 - "EAP, CG32099, BcDNA:GH12334, eap" IPR008278:4'-phosphopantetheinyl transferase superfamily CG32099 11-Aug-17 DroID_v2017_08 Drer\aasdhppt Scer\LYS5 "Cele\T28H10.1, Cele\T04G9.4" Xtro\aasdhppt Mmus\Aasdhppt Hsap\AASDHPPT DRSC21352 K 0.284940174 0.33597045 0.020639856 -0.551999988 0.735653712 2.250716873 FBgn0032318 CG14072 - http://flybase.org/reports/FBgn0032318 protein_coding_gene - - - CG14072 - CG14072 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064170 l(3)3-7E lethal (3) 3-7E http://flybase.org/reports/FBgn0064170 gene - - - l(3)3-7E - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0000790 fs(1)C6 female sterile (1) C6 http://flybase.org/reports/FBgn0000790 - gene - - - fs(1)C6 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "chorion,ovary" FBgn0000213 brb broad abdomen http://flybase.org/reports/FBgn0000213 - gene - - - brb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile,recessive,eye color defective" "pigment cell,wing,adult thorax,adult abdomen,macrochaeta,eye" FBgn0036141 wls wntless http://flybase.org/reports/FBgn0036141 protein_coding_gene Wnt-protein binding ; GO:0017147 | inferred from physical interaction with UniProtKB:P09615 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KVL7 Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype peptide secretion ; GO:0002790 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype positive regulation of protein secretion ; GO:0050714 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype regulation of intracellular protein transport ; GO:0033157 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype positive regulation of Wnt protein secretion ; GO:0061357 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay intrinsic component of endosome membrane ; GO:0031302 | inferred from direct assay integral component of synaptic vesicle membrane ; GO:0030285 | inferred from direct assay intrinsic component of Golgi membrane ; GO:0031228 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay extracellular exosome ; GO:0070062 | inferred from direct assay presynaptic membrane ; GO:0042734 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay multivesicular body ; GO:0005771 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay postsynaptic membrane ; GO:0045211 | inferred from direct assay intrinsic component of endoplasmic reticulum membrane ; GO:0031227 | inferred from direct assay "Wls, wls, CG6210, Evi, srt, Evi/Wls, evi, Wls/Evi, wls/evi, Srt" IPR009551:Protein wntless CG6210 11-Aug-17 DroID_v2017_08 Drer\wls - Cele\mig-14 Xtro\wls Mmus\Wls Hsap\WLS "lethal - all die before end of embryonic stage,germline clone,rescuable maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,visible,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,female sterile,male sterile,lethal,viable,fertile,segment polarity phenotype,maternal effect" "embryonic/first instar larval cuticle,germline clone,rescuable maternal effect,wing margin bristle,somatic clone,wing vein L1,wing,wing margin,leg,arista,adult antennal segment,mesothoracic tergum,testis,ovary,denticle belt,maternal effect,supernumerary,larva,eye" FBgn0011187 l(1)296-8 lethal (1) 296-8 http://flybase.org/reports/FBgn0011187 FBgn0010201 gene - - - "296-8, l(1)296-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053744 snmRNA:430:CR33744 snmRNA:430:CR33744 http://flybase.org/reports/FBgn0053744 non_protein_coding_gene - - - "CR33744, snmRNA:430:CR33744" - CR33744 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010369 espc extra sensory photoreceptor cells http://flybase.org/reports/FBgn0010369 - gene - - - "espc, esp" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259616 B1505 - http://flybase.org/reports/FBgn0259616 gene - - - B1505 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing margin bristle,submarginal cell,posterior cell,leg,unguis,antennal segment,arista,wing" FBgn0265666 CR44473 - http://flybase.org/reports/FBgn0265666 non_protein_coding_gene - - - CR44473 - CR44473 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038966 pinta prolonged depolarization afterpotential (PDA) is not apparent http://flybase.org/reports/FBgn0038966 protein_coding_gene retinoid binding ; GO:0005501 | inferred from direct assay rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype - "CT33362, pinta, CG13848, Pinta, PINTA" "IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG13848 11-Aug-17 DroID_v2017_08 "Drer\ttpal, Drer\sec14l7, Drer\clvs2, Drer\ttpa, Drer\sec14l8, Drer\rlbp1a, Drer\rlbp1b" "Scer\SFH5, Scer\YKL091C, Scer\SEC14" - "Xtro\clvs1, Xtro\rlbp1, Xtro\sec14l1, Xtro\ttpal, Xtro\clvs2, Xtro\sec14l3, Xtro\mospd2, Xtro\sec14l5, Xtro\ttpa" "Mmus\Clvs2, Mmus\Sec14l1, Mmus\Sec14l4, Mmus\Ttpal, Mmus\Ttpa, Mmus\Clvs1, Mmus\Sec14l2, Mmus\Sec14l5, Mmus\Sec14l3, Mmus\Rlbp1" "Hsap\RLBP1, Hsap\CLVS2, Hsap\SEC14L2, Hsap\TTPAL, Hsap\CLVS1, Hsap\SEC14L5, Hsap\SEC14L1, Hsap\SEC14L6, Hsap\SEC14L3, Hsap\SEC14L4, Hsap\TTPA" "neurophysiology defective,viable" FBgn0086608 CG34112 - http://flybase.org/reports/FBgn0086608 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34112, CG41471, CG14649" - CG34112 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025799 Su(var)1002 Suppressor of variegation 1002 http://flybase.org/reports/FBgn0025799 - gene - - - "Su-var(3)1002, Su(var)1002" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024196 robl roadblock http://flybase.org/reports/FBgn0024196 FBgn0021950 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity dynein intermediate chain binding ; GO:0045505 | inferred from direct assay" dendrite morphogenesis ; GO:0048813 | traceable author statement mushroom body development ; GO:0016319 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity axonemal dynein complex ; GO:0005858 | inferred from mutant phenotype dynein complex ; GO:0030286 | inferred from sequence or structural similarity cytoplasmic dynein complex ; GO:0005868 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "DLC, CG10751, l(2)k10408, robl, LC7, roblk" "IPR004942:Roadblock/LAMTOR2 domain, IPR016561:Dynein light chain roadblock-type 1/2" CG10751 11-Aug-17 DroID_v2017_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb1, Xtro\dynlrb2" "Mmus\Dynlrb1, Mmus\Dynlrb2" "Hsap\DYNLRB1, Hsap\DYNLRB2" " embryonic stage , larval stage " "viable,fertile,wild-type,paralytic,posterior,recessive,decreased cell number,somatic clone,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "imaginal disc,segmental nerve,eye,macrochaeta,mitotic cell cycle,mitosis & nuclear chromosome,mitotic anaphase,mitotic telophase,adult mushroom body,somatic clone,dendrite | somatic clone,embryonic/larval mushroom body,class IV dendritic arborizing neuron,dendrite | third instar larval stage,trichogen cell" FBgn0264786 CR44016 - http://flybase.org/reports/FBgn0264786 non_protein_coding_gene - - - "CR44016, lincRNA.974" - CR44016 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029929 CG4593 - http://flybase.org/reports/FBgn0029929 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG4593 IPR008532:Domain of unknown function DUF814 CG4593 11-Aug-17 DroID_v2017_08 Drer\ccdc25 Scer\JLP2 "Cele\F43C1.7, Cele\Y54G11A.2" Xtro\ccdc25 Mmus\Ccdc25 Hsap\CCDC25 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell" FBgn0052106 CG32106 - http://flybase.org/reports/FBgn0052106 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GH24302, CG32106, mlncRNA69E2" - CG32106 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032337 AstCC Allatostatin double C http://flybase.org/reports/FBgn0032337 protein_coding_gene hormone activity ; GO:0005179 | inferred from sequence or structural similarity with AstC biological regulation ; GO:0065007 | inferred from sequence or structural similarity with AstC cellular_component ; GO:0005575 | no biological data available "CG14920, Ast-CC, ASTCC, ASCC, AstCC" - CG14920 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0040510 ACXA ACXA http://flybase.org/reports/FBgn0040510 protein_coding_gene adenylate cyclase activity ; GO:0004016 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 adenylate cyclase activity ; GO:0004016 | inferred from sequence model intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 spermatogenesis ; GO:0007283 | inferred from expression pattern signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 "integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG17176, AC, DACXA, AC62D, Ac62D, ACXA" "IPR029787:Nucleotide cyclase, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase" CG17176 11-Aug-17 DroID_v2017_08 "Drer\adcy1b, Drer\adcy6b, Drer\adcy2a, Drer\adcy7, Drer\adcy5, Drer\adcy1a, Drer\si:ch211-132f19.7, Drer\adcy8, Drer\adcy6a, Drer\adcy3a, Drer\si:dkey-206f10.1, Drer\adcy2b" - "Cele\acy-3, Cele\acy-4, Cele\acy-2" "Xtro\adcy4, Xtro\adcy1, Xtro\adcy6, Xtro\adcy7, Xtro\dnajc27" "Mmus\Adcy4, Mmus\Adcy2, Mmus\Adcy3, Mmus\Adcy5, Mmus\Adcy6, Mmus\Adcy8, Mmus\Adcy1, Mmus\Adcy7" "Hsap\ADCY7, Hsap\ADCY5, Hsap\ADCY8, Hsap\ADCY3, Hsap\ADCY1, Hsap\ADCY2, Hsap\ADCY6, Hsap\ADCY4" " adult stage | male && spermatogenesis , adult stage | male , larval stage | late , pupal stage " " spermatocyte

, spermatid | early

" viable DRSC00844 K -0.367789239 0.19537325 -0.298719462 0.192029597 2.086526656 0.074641011 FBgn0040013 CG17164 - http://flybase.org/reports/FBgn0040013 protein_coding_gene - - - CG17164 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040503 CG7763 - http://flybase.org/reports/FBgn0040503 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - "CK02422a, CK02422A, BEST:CK02422, CG7763" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG7763 11-Aug-17 DroID_v2017_08 "Drer\clec3bb, Drer\clec3ba, Drer\clec11a, Drer\hbl4, Drer\hbl3, Drer\si:dkey-83f18.10, Drer\colec11, Drer\hbl2, Drer\si:ch73-361h17.1, Drer\hbl1" - "Cele\clec-178, Cele\F52E1.2, Cele\clec-149, Cele\clec-145" "Xtro\colec10, Xtro\clec3b, Xtro\colec11, Xtro\reg4, Xtro\clec3a" "Mmus\Clec11a, Mmus\Sftpa1, Mmus\Sell, Mmus\Sftpd, Mmus\Mbl1, Mmus\Clec3b, Mmus\Colec10, Mmus\Colec11, Mmus\Mbl2" "Hsap\COLEC10, Hsap\CLEC11A, Hsap\CLEC3A, Hsap\SFTPA2, Hsap\COLEC11, Hsap\SFTPA1, Hsap\SFTPD, Hsap\MBL2" viable FBgn0265419 CR44331 - http://flybase.org/reports/FBgn0265419 non_protein_coding_gene - - - CR44331 - CR44331 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031692 TpnC25D Troponin C at 25D http://flybase.org/reports/FBgn0031692 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "CG6514, TnC, DmTpnCII, DmTpnC25D, TpnC II, anon-EST:Posey103, BcDNA:RE53289, TpnC25D, TpnCII, TNC25D, Tnc5" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG6514 11-Aug-17 DroID_v2017_08 "Drer\calm3a, Drer\calb2a, Drer\calb1, Drer\scgn, Drer\efcab11, Drer\caln1, Drer\calm3b, Drer\cabp2b, Drer\caln2, Drer\tnnc2, Drer\pvalb3, Drer\calm1a, Drer\pvalb2, Drer\rhbdl3, Drer\pvalb8, Drer\cabp5b, Drer\pvalb9, Drer\efcab2, Drer\tnnc1b, Drer\tnnc1a, Drer\calm1b, Drer\calm2a, Drer\efcab6, Drer\pvalb1, Drer\calml4b, Drer\calm2b, Drer\cabp7b, Drer\pvalb4, Drer\cabp4, Drer\cabp1a, Drer\calb2b, Drer\pvalb6, Drer\cabp1b, Drer\cabp2a, Drer\cabp5a, Drer\calml4a, Drer\si:ch211-197n1.2" "Scer\MLC2, Scer\CDC31, Scer\CMD1, Scer\MLC1" "Cele\cal-4, Cele\pat-10, Cele\tnc-2, Cele\cal-1, Cele\cal-2, Cele\cal-3, Cele\cmd-1" "Xtro\cabp7, Xtro\LOC548651, Xtro\efcab6, Xtro\tnnc1, Xtro\pgm1, Xtro\pvalb, Xtro\ocm, Xtro\calml4, Xtro\cabp4, Xtro\calm1, Xtro\pvalb.2, Xtro\tnnc2, Xtro\scgn, Xtro\ocm.2, Xtro\pvalb.1, Xtro\calm2, Xtro\calb1" "Mmus\Cabp7, Mmus\Tnnc2, Mmus\Cabp5, Mmus\Calm5, Mmus\Efcab9, Mmus\Scgn, Mmus\1700023F06Rik, Mmus\Caln1, Mmus\Ocm, Mmus\Tnnc1, Mmus\Calm4, Mmus\Efcab3, Mmus\Spata21, Mmus\Calm2, Mmus\Calb2, Mmus\Pvalb, Mmus\Rhbdl3, Mmus\Calb1, Mmus\Calm1, Mmus\Calm3, Mmus\Calml4, Mmus\Cabp4, Mmus\Cabp2, Mmus\Efcab7, Mmus\Calml3, Mmus\Efcab11, Mmus\Cabp1, Mmus\Efcab6, Mmus\Efcab2" "Hsap\EFCAB3, Hsap\EFCAB11, Hsap\OCM2, Hsap\EFCAB9, Hsap\CALN1, Hsap\EFCAB13, Hsap\OCM, Hsap\EFCAB7, Hsap\CABP1, Hsap\CALML5, Hsap\PVALB, Hsap\SPATA21, Hsap\TNNC2, Hsap\CABP5, Hsap\CABP7, Hsap\SCGN, Hsap\TNNC1, Hsap\CALM2, Hsap\CALML3, Hsap\CABP4, Hsap\CABP2, Hsap\RHBDL3, Hsap\CALB1, Hsap\CALB2, Hsap\CALML6, Hsap\CALML4, Hsap\CALM1, Hsap\EFCAB2, Hsap\CALM3, Hsap\EFCAB6" viable FBgn0031906 CG5160 - http://flybase.org/reports/FBgn0031906 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR020849" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 neurogenesis ; GO:0022008 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available CG5160 "IPR001806:Small GTPase superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG5160 11-Aug-17 DroID_v2017_08 "Drer\rasd1, Drer\rasl12, Drer\si:dkeyp-59c12.1, Drer\rap1aa, Drer\rem2, Drer\diras1b, Drer\si:dkey-27j5.5, Drer\rheb, Drer\rras2, Drer\diras2, Drer\ralba, Drer\diras1a, Drer\kras, Drer\zgc:114118, Drer\rerglb, Drer\hrasa, Drer\rap2b, Drer\zgc:153845, Drer\gem, Drer\rap1ab, Drer\ralbb, Drer\rras, Drer\rergla, Drer\rem1, Drer\LOC100332969, Drer\mras, Drer\rasl11b, Drer\rhebl1, Drer\rasl11a, Drer\ralab, Drer\zgc:64022, Drer\zgc:110699, Drer\rit1, Drer\si:ch73-116o1.2, Drer\zgc:152698, Drer\nras, Drer\hrasb, Drer\rsg1, Drer\ralaa, Drer\rap2ab, Drer\zgc:171704, Drer\rap2c, Drer\rasl10a, Drer\rrad" "Scer\RAS1, Scer\RSR1, Scer\RHB1, Scer\RAS2" - "Xtro\rasd1, Xtro\rala, Xtro\rerg, Xtro\rap2b, Xtro\ralb, Xtro\nras, Xtro\kras, Xtro\rergl, Xtro\rasl11b, Xtro\rap1b, Xtro\LOC733456, Xtro\rap2c, Xtro\rrad, Xtro\rasl10a, Xtro\rhebl1, Xtro\LOC100145332, Xtro\rap1a, Xtro\hras, Xtro\diras1, Xtro\rem2, Xtro\rem1, Xtro\rasd2, Xtro\gem, Xtro\rheb, Xtro\diras3, Xtro\rsg1, Xtro\ras-dva, Xtro\rap2a, Xtro\diras2, Xtro\rit1" "Mmus\Rhebl1, Mmus\Gem, Mmus\Rrad, Mmus\Ralb, Mmus\Rap2a, Mmus\Rasd1, Mmus\Mras, Mmus\Eras, Mmus\Rap1b, Mmus\Rap1a, Mmus\Rerg, Mmus\Rit1, Mmus\Rasl11b, Mmus\Nras, Mmus\Rem2, Mmus\Rem1, Mmus\Rergl, Mmus\Rasl11a, Mmus\Kras, Mmus\Diras2, Mmus\Rras2, Mmus\Rasl10b, Mmus\Rras, Mmus\Rasd2, Mmus\Rap2c, Mmus\Diras1, Mmus\Rap2b, Mmus\Rasl10a, Mmus\Rasl12, Mmus\Rheb, Mmus\Rala, Mmus\Rit2, Mmus\Gm266, Mmus\Rsg1, Mmus\Hras" "Hsap\RRAS, Hsap\RASL12, Hsap\RALB, Hsap\RSG1, Hsap\RERG, Hsap\RHEB, Hsap\RALA, Hsap\REM1, Hsap\RASD1, Hsap\RIT1, Hsap\DIRAS2, Hsap\KRAS, Hsap\MRAS, Hsap\RAP2A, Hsap\GEM, Hsap\REM2, Hsap\RASL11A, Hsap\HRAS, Hsap\RHEBL1, Hsap\RASL11B, Hsap\RERGL, Hsap\RAP1B, Hsap\RRAS2, Hsap\DIRAS3, Hsap\RAP1A, Hsap\RRAD, Hsap\RASD2, Hsap\RASL10A, Hsap\RASL10B, Hsap\ERAS, Hsap\RIT2, Hsap\RAP2B, Hsap\NRAS, Hsap\RAP2C, Hsap\DIRAS1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0004455 DebC Developmental embryonic C http://flybase.org/reports/FBgn0004455 - gene - - - "Deb, Deb-C, DebC" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028897 CG4935 - http://flybase.org/reports/FBgn0028897 protein_coding_gene protein complex scaffold ; GO:0032947 | inferred from sequence or structural similarity with SGD:S000000402 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "MET30, BG:DS02740.2, CG4935" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR020472:G-protein beta WD-40 repeat" CG4935 11-Aug-17 DroID_v2017_08 Drer\wdr83 Scer\PRP46 Cele\F33G12.2 Xtro\wdr83 Mmus\Wdr83 Hsap\WDR83 viable FBgn0052275 CG32275 - http://flybase.org/reports/FBgn0052275 protein_coding_gene - - - CG32275 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22780 I -0.511997249 1.599659307 0.12872382 0.507317532 -1.184750344 -0.588886774 FBgn0058290 CG40290 - http://flybase.org/reports/FBgn0058290 protein_coding_gene - - - CG40290 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267651 pre-mod(mdg4)-O - http://flybase.org/reports/FBgn0267651 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-O, CG45989" "IPR007588:Zinc finger, FLYWCH-type" CG45989 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Flywch1, Mmus\Flywch2" - FBgn0001572 l(1)55 lethal (1) 55 http://flybase.org/reports/FBgn0001572 - gene - - - l(1)55 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable,male,poor" FBgn0035111 Dis3l2 Dis3 like 3'-5' exoribonuclease 2 http://flybase.org/reports/FBgn0035111 protein_coding_gene 3'-5'-exoribonuclease activity ; GO:0000175 | inferred from direct assay 3'-5'-exoribonuclease activity ; GO:0000175 | inferred from biological aspect of ancestor with PANTHER:PTN000599170 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000599170 miRNA catabolic process ; GO:0010587 | inferred from biological aspect of ancestor with PANTHER:PTN001156591 tRNA catabolic process ; GO:0016078 | inferred from mutant phenotype exosome (RNase complex) ; GO:0000178 | inferred from biological aspect of ancestor with PANTHER:PTN000599170 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000599278 "CG16940, Dis3l2, dmDis3l2, dmdis3l2" "IPR012340:Nucleic acid-binding, OB-fold, IPR022966:Ribonuclease II/R, conserved site" CG16940 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97a13.6, Drer\dis3l, Drer\dis3l2, Drer\helz2, Drer\dis3" "Scer\SSD1, Scer\DSS1, Scer\DIS3" "Cele\dis-3, Cele\disl-2" "Xtro\dis3l, Xtro\dis3l2, Xtro\dis3" "Mmus\Dis3, Mmus\Dis3l2, Mmus\Helz2, Mmus\Dis3l" "Hsap\DIS3L2, Hsap\HELZ2, Hsap\DIS3, Hsap\DIS3L" FBgn0011887 tRNA:Lys-CTT-1-4 transfer RNA:Lysine-CTT 1-4 http://flybase.org/reports/FBgn0011887 "FBgn0003795, FBgn0011886, FBgn0050312, FBgn0060184" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "35SLys, tRNA[Lys][[2]], AE002769.trna14-LysCTT, tRNA:K2, tRNA:K:CTT:AE002769-e, tRNA:lys2:42Aa, CR30312, tRNAlys, tRNA-Lys, chr2R.trna6-LysCTT, tRNA-Lys-CTT-1-4, tRNA:Lys-CTT-1-4, tRNA:K2:42Aa, AAG" - CR30312 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085476 CG34447 - http://flybase.org/reports/FBgn0085476 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid metabolic process ; GO:0006629 | inferred from sequence or structural similarity with UniProtKB:P81139 cellular_component ; GO:0005575 | no biological data available "CG34447, CG31684, CG9966" "IPR033906:Lipase, N-terminal, IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG34447 11-Aug-17 DroID_v2017_08 "Drer\LOC101884800, Drer\lipca, Drer\lipib, Drer\LOC100331214, Drer\lpl, Drer\pla1a, Drer\lipia, Drer\lipg" - - "Xtro\lipg, Xtro\lpl" "Mmus\Liph, Mmus\Lpl, Mmus\Pnliprp2, Mmus\Pnliprp1, Mmus\Pnlip, Mmus\Lipc, Mmus\Lipg, Mmus\Pla1a, Mmus\Lipi" "Hsap\PNLIPRP2, Hsap\LIPC, Hsap\LIPG, Hsap\PLA1A, Hsap\LIPH, Hsap\LIPI, Hsap\LPL, Hsap\PNLIPRP1, Hsap\PNLIPRP3, Hsap\PNLIP" FBgn0065243 l(2)SH2147 lethal (2) SH2147 http://flybase.org/reports/FBgn0065243 gene - - - "l(2)SH2147, l(2)SH2 2147" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0012026 tRNA:Tyr-GTA-1-6 transfer RNA:Tyrosine-GTA 1-6 http://flybase.org/reports/FBgn0012026 "FBgn0003849, FBgn0012014, FBgn0051434, FBgn0060003" tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "Tyr-tRNA T85c, tRNA-Tyr, 85Ac, tRNA[Tyr][[1gamma]], AE002708.trna59-TyrGTA, tRNA:Y, tRNA:Y:GTA:AE002708-c, CR31434, tRNA:tyr1:85Ac, tRNA[Tyr], chr3R.trna65-TyrGTA, tRNA-Tyr-GTA-1-6, tRNA:Tyr-GTA-1-6, tRNA:Y1:85Ac, UAC" - CR31434 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005028 dwh dwarfish http://flybase.org/reports/FBgn0005028 - gene - - - dwh - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,eye,leg,adult abdomen,adult thorax" FBgn0261518 l(2)k08617 lethal (2) k08617 http://flybase.org/reports/FBgn0261518 gene - - - l(2)k08617 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034951 CG3860 - http://flybase.org/reports/FBgn0034951 protein_coding_gene - - - CG3860 "IPR000648:Oxysterol-binding protein, IPR018494:Oxysterol-binding protein, conserved site" CG3860 11-Aug-17 DroID_v2017_08 "Drer\osbpl3b, Drer\osbpl7, Drer\si:ch211-106a19.1, Drer\osbpl3a, Drer\osbp2, Drer\LOC100331149, Drer\osbpl1a, Drer\osbpl2a, Drer\osbpl6, Drer\osbpl2b, Drer\osbp" "Scer\OSH6, Scer\OSH7, Scer\OSH2, Scer\SWH1, Scer\OSH3" "Cele\obr-2, Cele\obr-1" "Xtro\osbp, Xtro\osbpl2, Xtro\osbpl3, Xtro\osbpl1a" "Mmus\Osbpl3, Mmus\Osbp, Mmus\Osbpl6, Mmus\Osbpl2, Mmus\Osbp2, Mmus\Osbpl7, Mmus\Osbpl1a" "Hsap\OSBP2, Hsap\OSBPL1A, Hsap\OSBPL3, Hsap\OSBPL2, Hsap\OSBPL7, Hsap\OSBP, Hsap\OSBPL6" FBgn0260293 GSd402 - http://flybase.org/reports/FBgn0260293 gene - - - GSd402 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0039940 CG17165 - http://flybase.org/reports/FBgn0039940 protein_coding_gene - - - CG17165 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036053 iPLA2-VIA calcium-independent phospholipase A2 VIA http://flybase.org/reports/FBgn0036053 protein_coding_gene - lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR002641 positive regulation of response to oxidative stress ; GO:1902884 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype - "iPLA2-VIA, CG6718" "IPR002110:Ankyrin repeat, IPR002641:Patatin-like phospholipase domain, IPR016035:Acyl transferase/acyl hydrolase/lysophospholipase, IPR020683:Ankyrin repeat-containing domain" CG6718 11-Aug-17 DroID_v2017_08 Drer\pla2g6 - "Cele\ipla-2, Cele\ipla-5, Cele\ipla-4, Cele\C45B2.6, Cele\ipla-3" Xtro\pla2g6 "Mmus\Pla2g6, Mmus\Tanc2" "Hsap\TANC2, Hsap\PLA2G6, Hsap\PNPLA8" FBgn0016780 anon-79Ba anon-79Ba http://flybase.org/reports/FBgn0016780 - gene - - - "T2, anon-79Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069168 mcl(3)Z1335 mcl(3)Z1335 http://flybase.org/reports/FBgn0069168 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1335 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0250793 ds::ft - http://flybase.org/reports/FBgn0250793 engineered_fusion_gene - - - ds::ft - - 11-Aug-17 DroID_v2017_08 - - - - - - "planar polarity defective,cell non-autonomous,somatic clone" trichome & abdominal tergite | somatic clone | cell non-autonomous‘±Tub84B.PL FBgn0086394 BG02181 - http://flybase.org/reports/FBgn0086394 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02181 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0046328 l(2)38DEa lethal (2) 38DEa http://flybase.org/reports/FBgn0046328 gene - - - "lethal in 38D/E, l(2)38DEa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019737 l(1)91-4 lethal (1) 91-4 http://flybase.org/reports/FBgn0019737 - gene - - - l(1)91-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062595 Mod(var)1539 Mod(var)1539 http://flybase.org/reports/FBgn0062595 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1539, Mod(var)1539" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0024606 olfJ150 olfactory J150 http://flybase.org/reports/FBgn0024606 - gene - - - olfJ150 - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0004500 fs(1)B4 female sterile (1) B4 http://flybase.org/reports/FBgn0004500 - gene - - - fs(1)B4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027547 CG1927 - http://flybase.org/reports/FBgn0027547 "FBgn0027776, FBgn0062082" protein_coding_gene - - - "BcDNA:GH11112, cDNA A, anon-62BCb, anon-WO0118547.340, CG1927" - CG1927 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0065791 l(2)SH0427 lethal (2) SH0427 http://flybase.org/reports/FBgn0065791 gene - - - l(2)SH0427 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043850 2033 2033 http://flybase.org/reports/FBgn0043850 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 2033 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "eye,morphogenetic furrow,ommatidium" FBgn0069953 CG41069 - http://flybase.org/reports/FBgn0069953 protein_coding_gene - - - "CG40180, CG41069" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263654 CG43645 - http://flybase.org/reports/FBgn0263654 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43645, mlncRNA36C10" - CG43645 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032453 CG6180 - http://flybase.org/reports/FBgn0032453 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6180 IPR008914:Phosphatidylethanolamine-binding protein CG6180 11-Aug-17 DroID_v2017_08 "Drer\mrpl38, Drer\pebp1, Drer\pebp4" "Scer\TFS1, Scer\MRPL35, Scer\YLR179C" "Cele\F40A3.3, Cele\Y69E1A.5" "Xtro\pebp1, Xtro\pebp4, Xtro\LOC100497751, Xtro\mrpl38" "Mmus\Pebp1, Mmus\Pebp4, Mmus\Mrpl38, Mmus\Pbp2" "Hsap\MRPL38, Hsap\PEBP4, Hsap\PEBP1" viable FBgn0030251 CG2145 - http://flybase.org/reports/FBgn0030251 protein_coding_gene endoribonuclease activity ; GO:0004521 | inferred from sequence or structural similarity with HGNC:14369 endoribonuclease activity ; GO:0004521 | inferred from sequence or structural similarity with UniProtKB:P21128 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:P21128 "RNA phosphodiester bond hydrolysis, endonucleolytic ; GO:0090502 | inferred from sequence or structural similarity with HGNC:14369" cellular_component ; GO:0005575 | no biological data available "CG2145, Dmel_CG2145" IPR018998:Endoribonuclease XendoU CG2145 11-Aug-17 DroID_v2017_08 "Drer\prg4b, Drer\endou, Drer\prg4a, Drer\endou2, Drer\endouc, Drer\si:dkey-222f8.3" - "Cele\K02A11.3, Cele\M60.2" "Xtro\LOC100497154, Xtro\endou, Xtro\prg4, Xtro\endou" "Mmus\Endou, Mmus\Pou3f3" "Hsap\POU3F3, Hsap\ENDOU" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0263041 CG43336 - http://flybase.org/reports/FBgn0263041 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model with InterPro:IPR001254" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model with InterPro:IPR001254" cellular_component ; GO:0005575 | no biological data available "CG43336, CG5302, SPH73" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan" CG43336 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.7, Drer\gzm3, Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.9, Drer\si:dkey-21e2.15, Drer\si:dkey-21e2.12" - - - "Mmus\Cma2, Mmus\Klk6, Mmus\Mcpt4, Mmus\Gzmf, Mmus\Mcpt8, Mmus\Ctsg, Mmus\Gzmd, Mmus\Gzmb, Mmus\Gzme, Mmus\Gzmg, Mmus\Cma1, Mmus\Gzmc, Mmus\Mcpt1, Mmus\Mcpt9" "Hsap\CTSG, Hsap\GZMH, Hsap\GZMB, Hsap\CMA1" FBgn0262754 Mst77Y-5Psi Male-specific pseudogene 77Y 5 http://flybase.org/reports/FBgn0262754 pseudogene_attribute - - - Mst77Y-5Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036919 Grasp65 Grasp65 http://flybase.org/reports/FBgn0036919 protein_coding_gene - wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype morphogenesis of follicular epithelium ; GO:0016333 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi stack ; GO:0005795 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay Golgi-associated vesicle ; GO:0005798 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG7809, Grasp65, dGRASP, GRASP65, dGrasp65, dgrasp, GRASP" "IPR024958:GRASP55/65 PDZ-like domain, IPR001478:PDZ domain, IPR007583:GRASP55/65" CG7809 11-Aug-17 DroID_v2017_08 "Drer\gorasp1b, Drer\gorasp2, Drer\gorasp1a" Scer\GRH1 Cele\Y42H9AR.1 "Xtro\gorasp1, Xtro\gorasp2" "Mmus\Gorasp1, Mmus\Gorasp2" "Hsap\GORASP1, Hsap\GORASP2" "viable,female sterile,germline clone" "wing,wing disc" FBgn0050356 CG30356 - http://flybase.org/reports/FBgn0050356 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay CG30356 IPR009071:High mobility group box domain CG30356 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0002247 l(3)68Da lethal (3) 68Da http://flybase.org/reports/FBgn0002247 - gene - - - "rsg8, l(3)rsg8, l(3)68Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030667 CG15599 - http://flybase.org/reports/FBgn0030667 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15599 - CG15599 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028032 l(3)S102211 lethal (3) S102211 http://flybase.org/reports/FBgn0028032 gene - - - "1022/11, l(3)S102211" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0010311 ms(3)76A ms(3)76A http://flybase.org/reports/FBgn0010311 - gene - - - ms(3)76A - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0250817 CR40465 - http://flybase.org/reports/FBgn0250817 non_protein_coding_gene - - - "CR40465, BcDNA:AT13310" - CR40465 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267085 CR45529 - http://flybase.org/reports/FBgn0267085 non_protein_coding_gene - - - CR45529 - CR45529 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001116 fliF flightless F http://flybase.org/reports/FBgn0001116 - gene - flight behavior ; GO:0007629 | inferred from mutant phenotype - "gmp, fliF" - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive,jumping defective,partially" "myofibril,Z disc" FBgn0025496 l(3)73Bh lethal (3) 73Bh http://flybase.org/reports/FBgn0025496 - gene - - - l(3)73Bh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259241 CG42339 - http://flybase.org/reports/FBgn0259241 protein_coding_gene polysaccharide binding ; GO:0030247 | inferred from electronic annotation with InterPro:IPR001212 scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001212 immune response ; GO:0006955 | inferred from electronic annotation with InterPro:IPR001212 - "CG42339, CG12626, CG15204" "IPR001212:Somatomedin B domain, IPR000884:Thrombospondin type-1 (TSP1) repeat" CG42339 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-178e17.3, Drer\si:dkey-7k24.5" - Cele\R17.3 - "Mmus\Sbspon, Mmus\Gm933" Hsap\SBSPON FBgn0263258 chas chascon http://flybase.org/reports/FBgn0263258 protein_coding_gene molecular_function ; GO:0003674 | no biological data available establishment of body hair or bristle planar orientation ; GO:0048104 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype muscle tendon junction ; GO:0005927 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "CG32556, chas, CG12989, CG12988, CG12987, EP-631" - CG32556 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002244 l(3)68Cf lethal (3) 68Cf http://flybase.org/reports/FBgn0002244 - gene - - - "rsg5, l(3)rsg5, l(3)68Cf" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266532 T:ctail-arr http://flybase.net/reports/FBgn0266532.html engineered_tag cytoplasmic tail of arr 11-Aug-17 DroID_v2017_08 FBgn0046666 anon-38C.30 anon-38C.30 http://flybase.org/reports/FBgn0046666 gene - - - "38C.30, anon-38C.30" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004515 CR Compensatory Response http://flybase.org/reports/FBgn0004515 - gene - - - "cr, cr[+], CR" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058231 CG40231 - http://flybase.org/reports/FBgn0058231 protein_coding_gene - - - CG40231 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000865 fs(1)M59 female sterile (1) M59 http://flybase.org/reports/FBgn0000865 - gene - - - fs(1)M59 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0262964 CR43275 - http://flybase.org/reports/FBgn0262964 pseudogene_attribute - - - CR43275 - CR43275 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035161 CG13898 - http://flybase.org/reports/FBgn0035161 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "CG13898, CBP7" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG13898 11-Aug-17 DroID_v2017_08 "Drer\caln2, Drer\efcab11, Drer\efcab6, Drer\pvalb6, Drer\pvalb3, Drer\pvalb4, Drer\pvalb9, Drer\pvalb8, Drer\calml4b, Drer\calm3a, Drer\pvalb2, Drer\calm2b, Drer\calm3b, Drer\calm2a, Drer\calm1b, Drer\efcab2, Drer\cabp1a, Drer\rhbdl3, Drer\caln1, Drer\calb2a, Drer\tnnc2, Drer\cabp2a, Drer\cabp5b, Drer\tnnc1b, Drer\scgn, Drer\pvalb1, Drer\calb1, Drer\calb2b, Drer\si:ch211-197n1.2, Drer\tnnc1a, Drer\calm1a, Drer\cabp7b, Drer\cabp5a, Drer\calml4a" "Scer\CMD1, Scer\CDC31, Scer\MLC2, Scer\MLC1" "Cele\cal-3, Cele\cal-4, Cele\cal-2, Cele\cal-5, Cele\F43C9.2, Cele\cal-1, Cele\cbn-1" "Xtro\cabp4, Xtro\calm1, Xtro\pvalb.1, Xtro\tnnc2, Xtro\pvalb, Xtro\calb1, Xtro\scgn, Xtro\calml4, Xtro\calm2, Xtro\ocm, Xtro\ocm.2, Xtro\efcab6, Xtro\cabp7, Xtro\LOC548651, Xtro\pvalb.2, Xtro\tnnc1, Xtro\pgm1" "Mmus\Rhbdl3, Mmus\Efcab3, Mmus\Caln1, Mmus\Ocm, Mmus\Efcab9, Mmus\Efcab6, Mmus\Calb1, Mmus\Efcab7, Mmus\Calm1, Mmus\Efcab2, Mmus\Tnnc1, Mmus\Cabp7, Mmus\Calml3, Mmus\Cabp4, Mmus\Calm2, Mmus\Cabp2, Mmus\Efcab11, Mmus\Calb2, Mmus\Pvalb, Mmus\Cabp5, Mmus\Calml4, Mmus\Efcab12, Mmus\Tnnc2, Mmus\1700023F06Rik, Mmus\Calm3, Mmus\Calm4, Mmus\Scgn, Mmus\Spata21, Mmus\Cabp1" "Hsap\CABP1, Hsap\EFCAB6, Hsap\CABP5, Hsap\CALML4, Hsap\TNNC2, Hsap\CABP4, Hsap\EFCAB12, Hsap\EFCAB9, Hsap\CALN1, Hsap\CABP2, Hsap\OCM2, Hsap\RHBDL3, Hsap\CALML5, Hsap\OCM, Hsap\EFCAB11, Hsap\EFCAB7, Hsap\CALM3, Hsap\EFCAB2, Hsap\TNNC1, Hsap\CALB2, Hsap\SCGN, Hsap\CALML6, Hsap\CALM1, Hsap\CABP7, Hsap\PVALB, Hsap\SPATA21, Hsap\EFCAB13, Hsap\CALML3, Hsap\CALB1, Hsap\CALM2, Hsap\EFCAB3" viable FBgn0015505 l(3)EGX13 lethal (3) EGX13 http://flybase.org/reports/FBgn0015505 - gene - - - l(3)EGX13 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023471 anon-30Fc anon-30Fc http://flybase.org/reports/FBgn0023471 - gene - - - anon-30Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086421 l(3)CHe lethal (3) CHe http://flybase.org/reports/FBgn0086421 gene - - - l(3)CHe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016875 l(2)39Ah lethal (2) 39Ah http://flybase.org/reports/FBgn0016875 - gene - - - "I243, l(2)39Ah" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0043367 EP1581 BEST:RE35685 http://flybase.org/reports/FBgn0043367 gene - - - "RE35685, EP(X)1581, EP1581, BEST:RE35685" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "scutellar bristle,trichogen cell,ectopic,tormogen cell" FBgn0031597 CG17612 - http://flybase.org/reports/FBgn0031597 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG17612 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG17612 11-Aug-17 DroID_v2017_08 "Drer\znf710a, Drer\znf366, Drer\zgc:162948, Drer\znf668, Drer\znf574, Drer\znf710b" - "Cele\zfp-2, Cele\klu-2, Cele\sdz-12, Cele\che-1, Cele\pag-3, Cele\fezf-1, Cele\Y55F3AM.14, Cele\C09F5.3" Xtro\znf668 "Mmus\Zfp668, Mmus\Zfp366, Mmus\Zfp592, Mmus\Zfp710" "Hsap\ZNF668, Hsap\ZNF366, Hsap\ZNF710, Hsap\ZNF592, Hsap\ZNF32, Hsap\ZNF532" "viable,fertile" FBgn0031100 CG1504 - http://flybase.org/reports/FBgn0031100 protein_coding_gene - - - "CT3673, CG1504, 1504" "IPR003591:Leucine-rich repeat, typical subtype, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5" CG1504 11-Aug-17 DroID_v2017_08 "Drer\lrit3b, Drer\lrit3a, Drer\lrit1a, Drer\LOC101882074, Drer\LOC100330212, Drer\si:dkey-52j6.3, Drer\prelp, Drer\lrit1b, Drer\lrrc53" - "Cele\dma-1, Cele\pan-1, Cele\lron-13, Cele\lron-12, Cele\lron-9, Cele\egg-6" Xtro\lum "Mmus\Lrit1, Mmus\Lrrc26, Mmus\Cpn2, Mmus\Lrg1, Mmus\Lrrc52, Mmus\Lgr5, Mmus\Nyx, Mmus\Chadl, Mmus\Tril, Mmus\Lgr6, Mmus\Lrit3" "Hsap\LGR5, Hsap\CPN2, Hsap\LRRC52, Hsap\LRG1, Hsap\LRRC26, Hsap\CHADL, Hsap\LRIT3, Hsap\LRIT1, Hsap\LGR6, Hsap\TRIL" viable FBgn0267607 CR45945 - http://flybase.org/reports/FBgn0267607 non_protein_coding_gene - - - CR45945 - CR45945 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053826 His2A:CG33826 His2A:CG33826 http://flybase.org/reports/FBgn0053826 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33826, His2A:CG33826" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33826 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-368j24.14, Drer\si:dkey-108k21.26, Drer\si:dkey-261m9.7, Drer\LOC100334934, Drer\si:dkey-261m9.15, Drer\LOC100332229, Drer\si:dkey-23a13.14, Drer\h2afy2, Drer\si:dkey-261m9.11, Drer\fbxl6, Drer\LOC100148591, Drer\zgc:195633, Drer\si:dkey-108k21.19, Drer\si:ch211-113a14.7, Drer\si:ch211-113a14.11, Drer\zgc:154164, Drer\LOC570115, Drer\h2afx, Drer\si:dkey-23a13.20, Drer\si:ch1073-159d7.11, Drer\si:dkey-108k21.15, Drer\si:ch73-36p18.5, Drer\si:ch1073-159d7.10, Drer\zgc:173652, Drer\si:ch211-113a14.16, Drer\zgc:114037, Drer\si:dkey-23a13.7, Drer\zgc:110434, Drer\zgc:101846, Drer\si:ch211-113a14.26, Drer\si:dkey-261m9.18, Drer\si:ch73-368j24.13, Drer\si:ch211-113a14.19" "Scer\HTA1, Scer\HTA2" "Cele\his-68, Cele\his-33, Cele\his-30, Cele\his-21, Cele\his-3, Cele\htas-1, Cele\his-12, Cele\his-7, Cele\his-65, Cele\his-47, Cele\his-51, Cele\his-61, Cele\his-57, Cele\his-43, Cele\his-16, Cele\his-53, Cele\his-35, Cele\his-19" "Xtro\h2afy2, Xtro\hist1h2ad, Xtro\h2afy, Xtro\hist1h2aj, Xtro\hist1h2aa, Xtro\hist1h2am, Xtro\hist1h2ah, Xtro\h2afj, Xtro\h2afx" "Mmus\H2afx, Mmus\H2afy2, Mmus\H2al1n, Mmus\H2afb1, Mmus\H2al1j, Mmus\Hist1h2ao, Mmus\Hist3h2a, Mmus\Hist1h2ah, Mmus\Hist2h2ac, Mmus\H2afj, Mmus\Hist1h2an, Mmus\Hist1h2ad, Mmus\H2al2b, Mmus\Hist2h3c1, Mmus\H2afy, Mmus\Hist1h2ai, Mmus\H2afb3, Mmus\Hist1h2ae, Mmus\Hist1h2ag, Mmus\Hist1h2ab, Mmus\Hist1h2ac, Mmus\H2al2c, Mmus\Gm14920, Mmus\Hist1h2ap, Mmus\Hist2h2ab, Mmus\Hist1h2aa, Mmus\Hist2h2aa2, Mmus\Hist2h2aa1, Mmus\Hist1h2ak, Mmus\Hist1h2af, Mmus\H2afb2" "Hsap\HIST1H2AB, Hsap\H2AFB2, Hsap\H2AFB3, Hsap\HIST2H2AB, Hsap\HIST1H2AD, Hsap\HIST1H2AL, Hsap\HIST3H2A, Hsap\HIST2H2AC, Hsap\HIST1H2AC, Hsap\HIST1H2AG, Hsap\H2AFY2, Hsap\HIST1H2AI, Hsap\HIST1H2AK, Hsap\HIST1H2AM, Hsap\H2AFX, Hsap\HIST1H2AA, Hsap\HIST2H2AA3, Hsap\HIST1H2AJ, Hsap\H2AFY, Hsap\HIST1H2AH, Hsap\HIST2H2AA4, Hsap\H2AFB1, Hsap\HIST1H2AE, Hsap\H2AFJ" FBgn0267020 CR45464 - http://flybase.org/reports/FBgn0267020 non_protein_coding_gene - - - CR45464 - CR45464 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005134 l(1)Y80 lethal (1) Y80 http://flybase.org/reports/FBgn0005134 - gene - - - l(1)Y80 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0050297 tRNA:Ile-AAT-1-2 transfer RNA:Isoleucine-AAT 1-2 http://flybase.org/reports/FBgn0050297 tRNA_gene AUU codon-amino acid adaptor activity ; GO:0033433 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033433 cytosol ; GO:0005829 | inferred by curator from GO:0033433 "AE002787.trna29-IleAAT, tRNA:I:AAT:AE002787-b, CR30297, chr2R.trna11-IleAAT, tRNA-Ile[AAU], tRNA-Ile-AAT-1-2, tRNA:Ile-AAT-1-2, tRNA:CR30297, AUU" - CR30297 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067763 l(1)B-56 lethal (1) B-56 http://flybase.org/reports/FBgn0067763 gene - - - l(1)B-56 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260371 GSd413 - http://flybase.org/reports/FBgn0260371 gene - - - GSd413 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0062626 Mod(var)1094 Mod(var)1094 http://flybase.org/reports/FBgn0062626 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1094, Mod(var)1094" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0024217 l(2)CA7 lethal (2) CA7 http://flybase.org/reports/FBgn0024217 - gene - - - l(2)CA7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035790 Cyp316a1 Cyp316a1 http://flybase.org/reports/FBgn0035790 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128 - "316a1, CG8540, Cyp316a1, cyp316a1, CYP316a1" IPR001128:Cytochrome P450 CG8540 11-Aug-17 DroID_v2017_08 "Drer\cyp4v8, Drer\cyp26b1, Drer\cyp4t8, Drer\cyp4v7, Drer\LOC100329425, Drer\cyp19a1b, Drer\cyp26c1, Drer\cyp26a1, Drer\cyp19a1a, Drer\cyp46a1.4, Drer\cyp46a1.2, Drer\cyp46a1.3, Drer\cyp20a1, Drer\cyp46a1.1, Drer\cyp4f3" "Scer\ERG5, Scer\DIT2" "Cele\cyp-31A3, Cele\cyp-31A2, Cele\cyp-32B1, Cele\cyp-42A1, Cele\cyp-31A5, Cele\cyp-32A1" "Xtro\cyp26a1, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\mgc108213, Xtro\cyp20a1, Xtro\cyp19a1, Xtro\cyp4v2, Xtro\cyp4b1.2, Xtro\cyp4f2, Xtro\LOC100487918, Xtro\cyp26b1, Xtro\cyp4b1, Xtro\cyp26c1" "Mmus\Cyp4f15, Mmus\Cyp20a1, Mmus\Cyp4f14, Mmus\Cyp4f18, Mmus\Cyp4b1, Mmus\Cyp4f37, Mmus\Cyp4a14, Mmus\Cyp4f16, Mmus\Cyp4f40, Mmus\Cyp4a10, Mmus\Cyp4f13, Mmus\Cyp19a1, Mmus\Cyp4v3, Mmus\Cyp4x1, Mmus\Cyp4f17, Mmus\Cyp26b1, Mmus\Cyp4a12b, Mmus\Cyp4a31, Mmus\Cyp46a1, Mmus\Cyp4f39, Mmus\Cyp4a12a, Mmus\Cyp4a32, Mmus\Cyp26c1, Mmus\Cyp26a1" "Hsap\CYP4A22, Hsap\CYP4A11, Hsap\CYP4X1, Hsap\CYP26C1, Hsap\CYP19A1, Hsap\CYP4F11, Hsap\CYP4Z1, Hsap\CYP46A1, Hsap\CYP20A1, Hsap\CYP4V2, Hsap\CYP26B1, Hsap\CYP4F2, Hsap\CYP4F12, Hsap\CYP4F22, Hsap\CYP4F3, Hsap\CYP26A1, Hsap\CYP4B1" viable FBgn0032250 holn1 hole-in-one http://flybase.org/reports/FBgn0032250 protein_coding_gene molecular_function ; GO:0003674 | no biological data available compound eye development ; GO:0048749 | inferred from mutant phenotype positive regulation of wound healing ; GO:0090303 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | inferred from mutant phenotype inferred from genetic interaction with Ras85D chaeta development ; GO:0022416 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity with HGNC:1656 nucleus ; GO:0005634 | inferred from direct assay U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000320122 "CG5198, holn1" IPR003169:GYF domain CG5198 11-Aug-17 DroID_v2017_08 Drer\cd2bp2 Scer\LIN1 Cele\teg-1 Xtro\clip4 Mmus\Cd2bp2 Hsap\CD2BP2 "lethal,wound healing defective,recessive,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage" "eye,scutellum,macrochaeta,ectopic,supernumerary,trichogen cell,wing vein,wing" FBgn0263396 sqd squid http://flybase.org/reports/FBgn0263396 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA 3'-UTR binding ; GO:0003730 | traceable author statement mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "pole plasm oskar mRNA localization ; GO:0045451 | inferred from expression pattern oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | traceable author statement dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | non-traceable author statement negative regulation of RNA splicing ; GO:0033119 | inferred from mutant phenotype oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype pole plasm mRNA localization ; GO:0019094 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | traceable author statement ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | traceable author statement germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | traceable author statement mRNA export from nucleus ; GO:0006406 | non-traceable author statement RNA export from nucleus ; GO:0006405 | traceable author statement" nucleus ; GO:0005634 | traceable author statement chromatin ; GO:0000785 | inferred from direct assay omega speckle ; GO:0035062 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleolus ; GO:0005730 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 cytoplasm ; GO:0005737 | traceable author statement "Sqd, sqd, SQD, hrp40, BcDNA:GM03761, CR33328, Hrp40, CG17791, CG16901, hnRNP 1, Squid, RRM3, l(3)j4B4, l(3)EP3631, HRP40, rrm3, Hrb87, l(3)j8E7, l(3)j6E3, fs(3)00048, Rbp3, Hrb87Fb, squid, hnRNP A" IPR000504:RNA recognition motif domain CG16901 11-Aug-17 DroID_v2017_08 "Drer\zcrb1, Drer\hnrnpa3, Drer\msi2a, Drer\hnrnpabb, Drer\msi2b, Drer\hnrnpa0a, Drer\hnrnpa0l, Drer\cirbpa, Drer\wu:fq32h04, Drer\ncoa5, Drer\hnrnpc, Drer\trnau1apb, Drer\hnrnpa1a, Drer\raly, Drer\hnrnpd, Drer\dazl, Drer\hnrnpaba, Drer\eif4h, Drer\hnrpdl, Drer\srsf10a, Drer\dazap1, Drer\hnrnpa1b, Drer\hnrnpa0b, Drer\eif4ba, Drer\rbm34, Drer\zgc:55733, Drer\trnau1apa" "Scer\RIM4, Scer\NAM8, Scer\NAB6, Scer\NSR1, Scer\NGR1, Scer\CWC2, Scer\HRP1, Scer\NOP12, Scer\NOP6, Scer\MRN1, Scer\MUD1" "Cele\sqd-1, Cele\msi-1, Cele\H28G03.1, Cele\R05D3.8" "Xtro\trnau1ap, Xtro\hnrnpa1, Xtro\hnrnpdl, Xtro\hnrnpc, Xtro\hnrnpd, Xtro\hnrnpab, Xtro\raly, Xtro\hnrnpa0, Xtro\eif4h, Xtro\dazap1, Xtro\dazl, Xtro\hnrnpa3, Xtro\eif4b, Xtro\ralyl, Xtro\msi1, Xtro\hnrnpa2b1, Xtro\cirbp, Xtro\rbm34" "Mmus\Srsf10, Mmus\Trnau1ap, Mmus\Gm21379, Mmus\Boll, Mmus\Hnrnpa3, Mmus\Msi2, Mmus\Msi1, Mmus\Hnrnpa2b1, Mmus\Hnrnpa1, Mmus\Rbm34, Mmus\Cirbp, Mmus\Hnrnpab, Mmus\Hnrnpc, Mmus\Eif4h, Mmus\Dazl, Mmus\Dazap1, Mmus\Zcrb1, Mmus\Hnrnpdl, Mmus\Hnrnpd, Mmus\Tra2b, Mmus\Raly, Mmus\Slirp, Mmus\Eif4b, Mmus\Rbm31y, Mmus\Hnrnpa0, Mmus\Srsf12" "Hsap\DAZ2, Hsap\RALY, Hsap\DAZ4, Hsap\HNRNPCL1, Hsap\DAZ1, Hsap\SLIRP, Hsap\CIRBP, Hsap\DAZ3, Hsap\DAZAP1, Hsap\EIF4H, Hsap\HNRNPC, Hsap\HNRNPA2B1, Hsap\EIF4B, Hsap\HNRNPA3, Hsap\DAZL, Hsap\MSI1, Hsap\RBM34, Hsap\RALYL, Hsap\HNRNPAB, Hsap\RBM3, Hsap\HNRNPD, Hsap\HNRNPA0, Hsap\TRNAU1AP, Hsap\SRSF10, Hsap\HNRNPDL, Hsap\BOLL, Hsap\MSI2, Hsap\HNRNPA1, Hsap\HNRNPA1L2" " oogenesis stage , adult stage | female , oogenesis stage && adult stage | female , oogenesis stage | stage S8-14 && adult stage | female " " egg chamber

, ovary

" DRSC29779 IK -1.687615485 -0.023446846 1.446615705 0.478368851 -2.491818654 0.657118281 FBgn0028077 l(3)S086802 lethal (3) S086802 http://flybase.org/reports/FBgn0028077 gene - - - "0868/02, l(3)S086802" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003456 anon-RNA:A1 anon-RNA:A1 http://flybase.org/reports/FBgn0003456 - non_protein_coding_gene - - - "snRNA-c, anon-RNA:A1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266970 CR45421 - http://flybase.org/reports/FBgn0266970 non_protein_coding_gene - - - CR45421 - CR45421 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065546 l(2)SH1050 lethal (2) SH1050 http://flybase.org/reports/FBgn0065546 gene - - - "l(2)SH1050, l(2)SH2 1050" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260300 GSd088 - http://flybase.org/reports/FBgn0260300 gene - - - GSd088 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058002 ND-AGGG NADH dehydrogenase (ubiquinone) AGGG subunit http://flybase.org/reports/FBgn0058002 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with HGNC_gene:NDUFB2; HGNC:7697 "CG40002, ND-AGGG" IPR026627:NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 CG40002 11-Aug-17 DroID_v2017_08 Drer\ndufb2 - Cele\F44G4.2 Xtro\ndufb2 Mmus\Ndufb2 Hsap\NDUFB2 FBgn0038209 CG9722 - http://flybase.org/reports/FBgn0038209 protein_coding_gene - - - CG9722 IPR006214:Bax inhibitor 1-related CG9722 11-Aug-17 DroID_v2017_08 "Drer\faim2a, Drer\grinab, Drer\faim2b, Drer\si:ch211-284o19.8, Drer\grinaa, Drer\tmbim1, Drer\zgc:110410, Drer\LOC566927, Drer\tmbim4" Scer\BXI1 "Cele\Y42H9AR.2, Cele\tmbi-4, Cele\xbx-6, Cele\tag-120" "Xtro\faim2, Xtro\tmbim1, Xtro\tmbim4" "Mmus\Tmbim4, Mmus\Faim2, Mmus\Tmbim7, Mmus\Tmbim1, Mmus\Grina" "Hsap\TMBIM1, Hsap\GRINA, Hsap\TMBIM4, Hsap\FAIM2" lethal FBgn0044452 Atg2 Autophagy-related 2 http://flybase.org/reports/FBgn0044452 protein_coding_gene molecular_function ; GO:0003674 | no biological data available pexophagy ; GO:0030242 | inferred from electronic annotation with InterPro:IPR026886 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype larval midgut histolysis ; GO:0035069 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000324023 wound healing ; GO:0042060 | inferred from mutant phenotype glycophagy ; GO:0061723 | inferred from mutant phenotype negative regulation of phosphatidylinositol 3-kinase signaling ; GO:0014067 | inferred from mutant phenotype nucleophagy ; GO:0044804 | inferred from biological aspect of ancestor with PANTHER:PTN000324023 mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000324023 macroautophagy ; GO:0016236 | inferred from mutant phenotype extrinsic component of membrane ; GO:0019898 | inferred from biological aspect of ancestor with PANTHER:PTN000324023 pre-autophagosomal structure ; GO:0000407 | inferred from sequence or structural similarity with SGD:S000005186 pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN000324023 "Atg2, ATG2, CG1241, EP3697, atg2" "IPR015412:Autophagy-related, C-terminal, IPR026849:Autophagy-related protein 2, IPR026854:Vacuolar protein sorting-associated protein 13, N-terminal domain, IPR026886:Autophagy-related protein 2, fungi/plants" CG1241 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-45o6.2, Drer\atg2b" Scer\ATG2 Cele\atg-2 "Xtro\atg2a, Xtro\atg2b" "Mmus\Atg2a, Mmus\Atg2b" "Hsap\ATG2A, Hsap\ATG2B" pupal stage salivary gland

"neuroanatomy defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "neuromuscular junction,NMJ bouton,anterior fascicle & synapse,intersegmental nerve,embryonic/larval midgut,embryonic/larval fat body,somatic clone | third instar larval stage" FBgn0050343 CG30343 - http://flybase.org/reports/FBgn0050343 protein_coding_gene tRNA-intron endonuclease activity ; GO:0000213 | inferred from electronic annotation with InterPro:IPR006677 molecular_function ; GO:0003674 | no biological data available "tRNA splicing, via endonucleolytic cleavage and ligation ; GO:0006388 | inferred from electronic annotation with InterPro:IPR006677 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available "BcDNA:GM04716, CG30343" "IPR006677:tRNA intron endonuclease, catalytic domain-like, IPR018593:tRNA-splicing endonuclease subunit Sen15" CG30343 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040887 CG33254 - http://flybase.org/reports/FBgn0040887 protein_coding_gene - - - "CG7418, BcDNA:RH26422, CG33254" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058338 CG40338 - http://flybase.org/reports/FBgn0058338 protein_coding_gene - - - CG40338 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034447 CG7744 - http://flybase.org/reports/FBgn0034447 protein_coding_gene - - - CG7744 "IPR018617:Ima1, N-terminal domain" CG7744 11-Aug-17 DroID_v2017_08 Drer\tmem201 - Cele\samp-1 - Mmus\Tmem201 Hsap\TMEM201 viable FBgn0023092 dh62 dh62 http://flybase.org/reports/FBgn0023092 - gene - - - dh62 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011488 l(3)neo58b lethal (3) neo58b http://flybase.org/reports/FBgn0011488 - gene - - - l(3)neo58b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011931 tRNA:Asn-GTT-1-6 transfer RNA:Asparagine-GTT 1-6 http://flybase.org/reports/FBgn0011931 "FBgn0003759, FBgn0050309, FBgn0050510, FBgn0060128" tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "asn-tRNA, AE002769.trna13-AsnGTT, tRNA:N:GTT:AE002769-f, tRNA:asn5:42Aa, CR30309, CR30510, chr2R.trna5-AsnGTT, tRNA-Asn-GTT-1-6, tRNA:Asn-GTT-1-6, tRNA:N5:42Aa, AAC" - CR30510 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005039 e(tu-K) enhancer of tumor K http://flybase.org/reports/FBgn0005039 - gene - - - e(tu-K) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039682 Obp99c Odorant-binding protein 99c http://flybase.org/reports/FBgn0039682 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 response to fungus ; GO:0009620 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "CG7584, Obp99b, 99c, Obp99c, DmelObp99c, Obp 99c" IPR006170:Pheromone/general odorant binding protein CG7584 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0051172 CG31172 - http://flybase.org/reports/FBgn0051172 protein_coding_gene - - - CG31172 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070001 BG01575 BG01575 http://flybase.org/reports/FBgn0070001 gene - - - BG01575 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0054040 CG34040 - http://flybase.org/reports/FBgn0054040 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1015, CG34040" IPR008472:Domain of unknown function DUF753 CG34040 11-Aug-17 DroID_v2017_08 - - "Cele\C54D10.13, Cele\D1081.6, Cele\F55B11.4, Cele\ZK757.10" - "Mmus\Ly6d, Mmus\Slurp2, Mmus\2010109I03Rik, Mmus\Lynx1" "Hsap\LY6D, Hsap\LYNX1" FBgn0000235 btm breaks at metaphase http://flybase.org/reports/FBgn0000235 - gene - - - "bam, btm" - - 11-Aug-17 DroID_v2017_08 - - - - - - mitotic cell cycle defective FBgn0266350 CR44999 - http://flybase.org/reports/FBgn0266350 non_protein_coding_gene - - - CR44999 - CR44999 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035690 CG10274 - http://flybase.org/reports/FBgn0035690 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 CG10274 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR012934:Zinc finger, AD-type" CG10274 11-Aug-17 DroID_v2017_08 "Drer\znf341, Drer\zgc:174268, Drer\znf770, Drer\znf1004, Drer\znf990, Drer\zgc:162948, Drer\si:dkey-33c14.6, Drer\znf668" Scer\ZAP1 "Cele\hinf-1, Cele\sem-4, Cele\Y37F4.6, Cele\ztf-16, Cele\Y55F3AM.14, Cele\eor-1, Cele\Y48G8AL.10, Cele\M03D4.4" Xtro\znf668 "Mmus\Zfp936, Mmus\Zfp341, Mmus\Zfp668, Mmus\Gm14432" "Hsap\ZNF341, Hsap\ZNF471, Hsap\ZNF668, Hsap\ZNF221, Hsap\ZNF317, Hsap\ZNF284" viable DRSC09716 K 0.492532681 0.30541536 0.460820667 -0.604529626 -0.377891507 2.032010074 FBgn0000699 fltE flight defective E http://flybase.org/reports/FBgn0000699 - gene - - - fltE - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0070042 3R-31-22 3R-31-22 http://flybase.org/reports/FBgn0070042 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-31-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0086657 IKKepsilon I-kappaB kinase epsilon http://flybase.org/reports/FBgn0086657 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V9Y9 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Diap1 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab30" "endocytic recycling ; GO:0032456 | inferred from mutant phenotype cell death ; GO:0008219 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from direct assay neuron remodeling ; GO:0016322 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype protein trans-autophosphorylation ; GO:0036290 | inferred from direct assay microtubule bundle formation ; GO:0001578 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043280 | inferred from mutant phenotype regulation of cytoskeleton organization ; GO:0051493 | inferred from physical interaction with spn-F innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000540280 actin filament organization ; GO:0007015 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement actin filament bundle organization ; GO:0061572 | inferred from mutant phenotype maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype sensory organ precursor cell division ; GO:0045035 | inferred from genetic interaction with Diap1 chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay cell tip ; GO:0051286 | inferred from direct assay "l(2)38Ea, APTX7, CG2615, Ik2, Ik2/DmIKK, dIKK, IK2, 38D.31, Dmik2, DIK2, dik2, Dik2, IKK, DmIKKepsilon, ik2, IKKepsilon, ikkepsilon, DmIKKepsilon/dIK2" "IPR011009:Protein kinase-like domain, IPR000719:Protein kinase domain, IPR017441:Protein kinase, ATP binding site, IPR029071:Ubiquitin-related domain" CG2615 11-Aug-17 DroID_v2017_08 "Drer\chuk, Drer\ikbkb, Drer\tbk1, Drer\ikbke" - "Cele\Y39G8B.5, Cele\ikke-1" "Xtro\ikbkb, Xtro\tbk1, Xtro\chuk" "Mmus\Ikbke, Mmus\Ikbkb, Mmus\Tbk1, Mmus\Chuk" "Hsap\IKBKB, Hsap\IKBKE, Hsap\TBK1, Hsap\CHUK" FBgn0085458 CG34429 - http://flybase.org/reports/FBgn0085458 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34429, CG14116" IPR006631:Protein of unknown function DM4/12 CG34429 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028562 sut2 sugar transporter 2 http://flybase.org/reports/FBgn0028562 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from electronic annotation with InterPro:IPR003663 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003663, InterPro:IPR005828" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 "CG17975, sut2" "IPR003663:Sugar/inositol transporter, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG17975 11-Aug-17 DroID_v2017_08 "Drer\LOC100331510, Drer\slc2a1b, Drer\slc2a15b, Drer\LOC100334818, Drer\slc2a15a, Drer\slc2a11b, Drer\slc2a1a, Drer\slc2a9l1, Drer\slc2a2, Drer\slc2a3b, Drer\slc2a11a, Drer\slc2a11l, Drer\slc2a3a" "Scer\HXT4, Scer\HXT14, Scer\YBR241C, Scer\VPS73" "Cele\F11D5.5, Cele\F11D5.7, Cele\Y37A1A.3, Cele\R09B5.11, Cele\K08F9.1, Cele\C35A11.4, Cele\F53H8.3, Cele\Y39E4B.5, Cele\fgt-1, Cele\Y39B6A.41, Cele\Y61A9LA.1, Cele\slcf-2, Cele\ZK829.9, Cele\K08H10.6, Cele\C03B1.13, Cele\F48E3.2, Cele\F13B12.2, Cele\K09C4.5, Cele\K09C4.4, Cele\K09C4.1, Cele\F14E5.1" "Xtro\slc2a11, Xtro\slc2a7, Xtro\slc2a1, Xtro\slc2a9, Xtro\slc2a2, Xtro\slc2a3, Xtro\LOC100496725, Xtro\slc2a5" "Mmus\Slc2a5, Mmus\Slc2a2, Mmus\Slc2a4, Mmus\Slc2a9, Mmus\Slc2a3, Mmus\Slc2a1, Mmus\Slc2a7" "Hsap\SLC2A7, Hsap\SLC2A2, Hsap\SLC2A14, Hsap\SLC2A4, Hsap\SLC2A3, Hsap\SLC2A5, Hsap\SLC2A11, Hsap\SLC2A9, Hsap\MIF, Hsap\SLC2A1" viable FBgn0266986 CR45437 - http://flybase.org/reports/FBgn0266986 non_protein_coding_gene - - - CR45437 - CR45437 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052109 CG32109 - http://flybase.org/reports/FBgn0052109 protein_coding_gene - - - "CG10982, CG32109" IPR019341:Alpha/gamma-adaptin-binding protein p34 CG32109 11-Aug-17 DroID_v2017_08 Drer\aagab - - Xtro\aagab Mmus\Aagab Hsap\AAGAB FBgn0036031 CG6761 - http://flybase.org/reports/FBgn0036031 protein_coding_gene - - - CG6761 IPR021777:Protein of unknown function DUF3342 CG6761 11-Aug-17 DroID_v2017_08 Drer\si:ch211-189k9.2 - - Xtro\kiaa1841 Mmus\0610010F05Rik Hsap\KIAA1841 FBgn0065958 l(2)SH0052 lethal (2) SH0052 http://flybase.org/reports/FBgn0065958 gene - - - l(2)SH0052 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262374 mir-2b-1 mir-2b-1 stem loop http://flybase.org/reports/FBgn0262374 miRNA_gene - negative regulation of translational initiation ; GO:0045947 | inferred from direct assay negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "mir-2b-1, mir-2b, dme-mir-2b-1, 2b-1/2, MIR-2, CR42893, miR-2b, miR-2, miR2b, miR-2b-1, CR32990, miR2, miR-2b1, dme-miR-2b, dme-miR-2b-3p" - CR42893 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage "visible,lethal" wing vein FBgn0004619 GluRIA Glutamate receptor IA http://flybase.org/reports/FBgn0004619 - protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 AMPA glutamate receptor activity ; GO:0004971 | inferred from biological aspect of ancestor with PANTHER:PTN000438080 kainate selective glutamate receptor activity ; GO:0015277 | inferred from direct assay cation transport ; GO:0006812 | inferred from direct assay AMPA glutamate receptor complex ; GO:0032281 | inferred from biological aspect of ancestor with PANTHER:PTN000438080 ionotropic glutamate receptor complex ; GO:0008328 | inferred by curator from GO:0015277 "dGluRI, DGluRI, dglur-IA, DGluR-IA, DGluR-I, CG8442, Glu-R1, GluRI, DmelGlu-R1, Glu-RI, GluRIA, Dro GluRIA, GluR1" "IPR001320:Ionotropic glutamate receptor, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG8442 11-Aug-17 DroID_v2017_08 "Drer\grik1b, Drer\gria1a, Drer\gria2b, Drer\gria4b, Drer\grik2, Drer\grik1a, Drer\gria2a, Drer\gria3a, Drer\gria3b, Drer\LOC100334689, Drer\gria4a, Drer\gria1b" - "Cele\glr-5, Cele\glr-4, Cele\glr-3, Cele\glr-1, Cele\glr-2" "Xtro\gria1, Xtro\grik1, Xtro\gria3, Xtro\gria4" "Mmus\Gria1, Mmus\Grik5, Mmus\Grik3, Mmus\Gria4, Mmus\Grik1, Mmus\Grik2, Mmus\Gria3, Mmus\Gria2" "Hsap\GRIK5, Hsap\GRIK2, Hsap\GRIK1, Hsap\GRIA2, Hsap\GRIK3, Hsap\GRIA1, Hsap\GRIA3, Hsap\GRIA4" embryonic stage | late " subesophageal ganglion

, ventral nerve cord

, supraesophageal ganglion

" "viable,fertile" FBgn0034377 CG15071 - http://flybase.org/reports/FBgn0034377 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG15071 - CG15071 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020625 P-1 proteoglycan-1 http://flybase.org/reports/FBgn0020625 - gene - - - "DROP-1, DP-1, P-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004662 mbd mushroom body deranged http://flybase.org/reports/FBgn0004662 "FBgn0002686, FBgn0002695" gene - mushroom body development ; GO:0016319 | inferred from mutant phenotype olfactory learning ; GO:0008355 | traceable author statement - "mdb, mbd, MBD" - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective "Kenyon cell,ellipsoid body,nodulus,adult central complex,neuropil,adult mushroom body,calyx of adult mushroom body,lobe system of adult mushroom body" FBgn0030908 CG15057 - http://flybase.org/reports/FBgn0030908 protein_coding_gene - - - CG15057 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0261973 snoRNA:Or-CD9a - http://flybase.org/reports/FBgn0261973 snoRNA_gene - - nucleoplasm ; GO:0005654 | inferred from direct assay "CR42804, DmOr_cd9a snoRNA, CR34566, snoRNA:Or-CD9a, DmOr_cd9a, snoRNA:Or-cd9a, orphan CD9a, CR34156, snmRNA:60Ca, Dmsnm60a, snm60, DmOrC/D_9a, Snm60a" - CR42804 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002956 nofL no object fixation L http://flybase.org/reports/FBgn0002956 - gene - - - nofL - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,visual behavior defective" "optic lobe,rhabdomere | adult stage,pigment cell" FBgn0264352 CR43808 - http://flybase.org/reports/FBgn0264352 non_protein_coding_gene - - - "CR43808, lincRNA.55" - CR43808 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011590 fms(445B) fms(445B) http://flybase.org/reports/FBgn0011590 - gene - - - fms(445B) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266563 EP985 - http://flybase.org/reports/FBgn0266563 gene - - - EP985 - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval salivary gland FBgn0069204 l(2)46Dj lethal (2) 46Dj http://flybase.org/reports/FBgn0069204 gene - - - l(2)46Dj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,dominant" wing FBgn0053365 5SrRNA:CR33365 5SrRNA:CR33365 http://flybase.org/reports/FBgn0053365 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33365, 5SrRNA:CR33365" - CR33365 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036361 CG10154 - http://flybase.org/reports/FBgn0036361 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG10154 IPR002557:Chitin binding domain CG10154 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\dct-9, Cele\C39D10.7, Cele\cbd-1" - - - viable FBgn0003510 Sry-alpha Serendipity alpha http://flybase.org/reports/FBgn0003510 - protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity cellularization ; GO:0007349 | traceable author statement cellularization ; GO:0007349 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cleavage furrow ; GO:0032154 | colocalizes_with inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay "Sryalpha, sryalpha, sry-alpha, sry alpha, Sry alpha, CG17957, sry, Sry-alpha, srya, sry-a, ser" IPR008837:Serendipity locus alpha CG17957 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | embryonic cycle 11 , embryonic stage | embryonic cycle 14 , embryonic stage | blastoderm , embryonic stage | stage 4-6 , embryonic stage | stage 4-8 , embryonic stage | early " " organism | 0-20% egg length

, organism | 40-80% egg length

" " embryonic stage | stage 5-7 , embryonic stage | early , embryonic stage | embryonic cycle 14 " "wild-type,viable" FBgn0031473 CG3104 - http://flybase.org/reports/FBgn0031473 protein_coding_gene cytoskeletal adaptor activity ; GO:0008093 | inferred from sequence or structural similarity with HGNC:492 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with HGNC:492 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:492 CG3104 "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG3104 11-Aug-17 DroID_v2017_08 "Drer\asb12a, Drer\asb4, Drer\ankrd29, Drer\asb12b, Drer\ankmy1, Drer\asb10" Scer\NAS6 Cele\mlt-4 Xtro\ankrd29 "Mmus\Ankrd29, Mmus\Asb12, Mmus\Ankmy1" "Hsap\ANKRD29, Hsap\ASB12, Hsap\ANKMY1" "viable,visible" trichogen cell FBgn0263085 CR43353 - http://flybase.org/reports/FBgn0263085 non_protein_coding_gene - - - "CR43353, CG43353, lincRNA.182" - CR43353 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033904 CG18327 - http://flybase.org/reports/FBgn0033904 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640628 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 CG18327 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG18327 11-Aug-17 DroID_v2017_08 "Drer\slc25a35, Drer\slc25a34, Drer\slc25a14" "Scer\DIC1, Scer\OAC1" "Cele\misc-1, Cele\mtch-1, Cele\slc-25A10" "Xtro\slc25a34, Xtro\slc25a30" "Mmus\Slc25a14, Mmus\Slc25a34, Mmus\Slc25a10, Mmus\Slc25a11, Mmus\Slc25a30, Mmus\Slc25a35" "Hsap\SLC25A10, Hsap\SLC25A35, Hsap\SLC25A30, Hsap\SLC25A11, Hsap\SLC25A14, Hsap\SLC25A34" "viable,fertile" FBgn0022710 Ac13E Adenylyl cyclase 35C http://flybase.org/reports/FBgn0022710 - protein_coding_gene adenylate cyclase activity ; GO:0004016 | inferred from direct assay guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 adenylate cyclase activity ; GO:0004016 | non-traceable author statement "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 cAMP biosynthetic process ; GO:0006171 | inferred from direct assay signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG9210, AC 13E, DAC9, Ac35C, Ac13E, AC13E, ac13e" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase" CG9210 11-Aug-17 DroID_v2017_08 Drer\adcy9 - Cele\acy-1 Xtro\adcy9 Mmus\Adcy9 Hsap\ADCY9 " adult stage , larval stage , embryonic stage -- adult stage " "viable,visible" trichogen cell FBgn0024302 Sbp3 Su(H)-binding protein 3 http://flybase.org/reports/FBgn0024302 - gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "sbp3, SBP3, Sbp3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263270 CG43396 - http://flybase.org/reports/FBgn0263270 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43396 - CG43396 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264444 CR43862 - http://flybase.org/reports/FBgn0264444 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR43862 - CR43862 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003089 pip pipe http://flybase.org/reports/FBgn0003089 - protein_coding_gene sulfotransferase activity ; GO:0008146 | inferred from mutant phenotype heparan sulfate 2-O-sulfotransferase activity ; GO:0004394 | non-traceable author statement heparan sulfate sulfotransferase activity ; GO:0034483 | NOT inferred from direct assay chondroitin sulfotransferase activity ; GO:0034481 | NOT inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O44342 "dorsal/ventral axis specification ; GO:0009950 | traceable author statement dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype inferred from genetic interaction with gd inferred from genetic interaction with ndl inferred from genetic interaction with wbl regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | traceable author statement protein processing ; GO:0016485 | inferred from genetic interaction with ea dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype oogenesis ; GO:0048477 | non-traceable author statement maternal specification of dorsal/ventral axis, oocyte, soma encoded ; GO:0007313 | traceable author statement embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR007734 chromosome ; GO:0005694 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay integral component of Golgi membrane ; GO:0030173 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay" "pip, pipe, pipe-ST2, CG9614, Pipe, l(3)76BDp" "IPR007734:Heparan sulphate 2-O-sulfotransferase, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR005331:Sulfotransferase" CG9614 11-Aug-17 DroID_v2017_08 "Drer\hs2st1b, Drer\ust, Drer\hs2st1a" - Cele\hst-2 Xtro\hs2st1 "Mmus\Hs2st1, Mmus\Ust" "Hsap\UST, Hsap\HS2ST1" " embryonic stage | stage >=12 , adult stage && oogenesis stage | stage S9-10 , embryonic stage , oogenesis stage , embryonic stage | stage >=14 " " embryonic/larval pharynx | anterior

, follicle cell | ventral

, gonad | presumptive

, embryonic/larval salivary gland

" "viable,fertile,partially lethal - majority die,developmental rate defective,small body" "embryonic/first instar larval cuticle,embryonic epidermis,maternal effect,somatic clone,denticle field,embryo,ventral,presumptive embryonic salivary gland" FBgn0001449 l(1)7Dc lethal (1) 7Dc http://flybase.org/reports/FBgn0001449 - gene - - - "l(1)VE470, l(1)7Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038088 CG10126 - http://flybase.org/reports/FBgn0038088 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000095441 neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CT28495, CG10126" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG10126 11-Aug-17 DroID_v2017_08 "Drer\camk1db, Drer\si:ch73-60h1.1, Drer\dapk1, Drer\uhmk1, Drer\camkva, Drer\camk1b, Drer\stk17a, Drer\camk1gb, Drer\zgc:153952, Drer\triob, Drer\dapk2a, Drer\dapk3, Drer\caps2, Drer\mylk4a, Drer\ttnb, Drer\camk1da, Drer\mylk3, Drer\camkvb, Drer\si:ch211-27e6.1, Drer\camk1a, Drer\stk17b, Drer\pskh1, Drer\capslb, Drer\stk33, Drer\dapk2b, Drer\capsla, Drer\camk1ga, Drer\mylk4b, Drer\pnck, Drer\camk4, Drer\camkvl, Drer\si:dkey-240h12.4, Drer\spegb, Drer\trioa" "Scer\CMK1, Scer\IKS1, Scer\TDA1, Scer\RCK2, Scer\CMK2, Scer\MEK1, Scer\RCK1" Cele\F43C9.2 "Xtro\camk4, Xtro\dapk1, Xtro\capsl, Xtro\stk17a, Xtro\dapk2, Xtro\camk1g, Xtro\pskh1, Xtro\mylk3, Xtro\stk33, Xtro\trio, Xtro\camk1, Xtro\caps, Xtro\kalrn, Xtro\dclk2, Xtro\camk1d, Xtro\camkv, Xtro\pnck, Xtro\pskh2, Xtro\dapk3, Xtro\mylk4" "Mmus\Trio, Mmus\Camkv, Mmus\Mylk2, Mmus\Capsl, Mmus\Stk33, Mmus\Dclk1, Mmus\Pskh1, Mmus\Camk1g, Mmus\Speg, Mmus\Dapk1, Mmus\Camk1, Mmus\Dapk2, Mmus\Pnck, Mmus\Caps2, Mmus\Obscn, Mmus\Camk1d, Mmus\Dapk3, Mmus\Stk17b, Mmus\Mylk3, Mmus\Camk4, Mmus\Mylk4, Mmus\Uhmk1, Mmus\Dclk2" "Hsap\DCLK1, Hsap\PSKH2, Hsap\CAMK1G, Hsap\STK17A, Hsap\PSKH1, Hsap\SPEG, Hsap\CAMK4, Hsap\STK17B, Hsap\CAPSL, Hsap\UHMK1, Hsap\OBSCN, Hsap\CAMKV, Hsap\PNCK, Hsap\CAMK1D, Hsap\MYLK4, Hsap\CAPS, Hsap\TRIO, Hsap\MYLK2, Hsap\STK33, Hsap\MYLK3, Hsap\DAPK2, Hsap\DAPK1, Hsap\CAMK1, Hsap\DAPK3, Hsap\CAPS2" "lethal,neuroanatomy defective,partially lethal - majority die" "embryonic/larval neuroblast,ganglion mother cell" FBgn0261720 Su(Gl)160 - http://flybase.org/reports/FBgn0261720 gene - - - Su(Gl)160 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011100 l(1)Q61 lethal (1) Q61 http://flybase.org/reports/FBgn0011100 FBgn0010210 gene - - - l(1)Q61 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266807 CR45269 - http://flybase.org/reports/FBgn0266807 non_protein_coding_gene - - - CR45269 - CR45269 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034919 CG5569 - http://flybase.org/reports/FBgn0034919 protein_coding_gene - mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from electronic annotation with InterPro:IPR034095 neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BcDNA:SD18780, CG5569" "IPR007523:NDUFAF3/Mth938 domain-containing protein, IPR034095:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3" CG5569 11-Aug-17 DroID_v2017_08 Drer\ndufaf3 - Cele\nuaf-3 Xtro\ndufaf3 Mmus\Ndufaf3 Hsap\NDUFAF3 "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0259400 EP-J17b - http://flybase.org/reports/FBgn0259400 gene - - - EP-J17b - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0016018 l(3)73CFa lethal (3) 73CFa http://flybase.org/reports/FBgn0016018 - gene - - - l(3)73CFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011461 l(3)neo27 lethal (3) neo27 http://flybase.org/reports/FBgn0011461 - gene - - - l(3)neo27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016975 stnB stoned B http://flybase.org/reports/FBgn0016975 "FBan0012473, FBgn0003533, FBgn0058306, FBgn0063778" protein_coding_gene scaffold protein binding ; GO:0097110 | inferred from physical interaction with Git protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P21521 inferred from physical interaction with UniProtKB:Q24211 synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype regulation of synaptic vesicle endocytosis ; GO:1900242 | inferred from mutant phenotype synaptic vesicle cycle ; GO:0099504 | inferred from expression pattern synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype vesicle coating ; GO:0006901 | traceable author statement chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype synaptic vesicle coating ; GO:0016183 | traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement integral component of membrane ; GO:0016021 | NOT inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay synaptic vesicle ; GO:0008021 | traceable author statement coated vesicle ; GO:0030135 | traceable author statement endocytic vesicle ; GO:0030139 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay cytoskeleton of presynaptic active zone ; GO:0048788 | colocalizes_with inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from genetic interaction with Syt1 inferred from physical interaction with Syb inferred from physical interaction with Csp inferred from physical interaction with Syt1 "CG12473, stn, stn-B, STNB, ORF2, CG40306, stnB, CG12473/CG12500, StnB" "IPR012320:Stonin homology, IPR028565:Mu homology domain, IPR017110:Stonin" CG12473 11-Aug-17 DroID_v2017_08 "Drer\gtf2a1, Drer\ston2, Drer\ston1, Drer\gtf2a1l" "Scer\TOA1, Scer\APM2, Scer\APM3, Scer\APM1" "Cele\pqn-51, Cele\unc-41" "Xtro\gtf2a1, Xtro\gtf2a1l" "Mmus\Ston1, Mmus\Gtf2a1, Mmus\Gtf2a1l, Mmus\Ston2" "Hsap\GTF2A1L, Hsap\STON1-GTF2A1L, Hsap\GTF2A1, Hsap\STON2, Hsap\STON1" adult stage adult stage " adult head

, adult abdomen

, adult thorax

" "uncoordinated,recessive,neurophysiology defective,lethal,behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,some die during pupal stage,short lived,neuroanatomy defective,viable" "axon terminus,synaptic vesicle,multivesicular body,embryonic/larval neuromuscular junction,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage,synaptic vesicle | third instar larval stage, with P{UAS-stnB.M}vl" FBgn0031662 CG3792 - http://flybase.org/reports/FBgn0031662 protein_coding_gene - dolichol-linked oligosaccharide biosynthetic process ; GO:0006488 | inferred from biological aspect of ancestor with PANTHER:PTN000259900 protein glycosylation ; GO:0006486 | inferred from sequence or structural similarity with UniProtKB:O75352 integral component of membrane ; GO:0016021 | inferred from sequence model "anon-EST:Posey8, CG3792" "IPR006603:PQ-loop repeat, IPR016817:Mannose-P-dolichol utilization defect 1 protein" CG3792 11-Aug-17 DroID_v2017_08 "Drer\mpdu1b, Drer\mpdu1a, Drer\pqlc3" - Cele\F38E1.9 "Xtro\pqlc3, Xtro\mpdu1" "Mmus\Pqlc3, Mmus\Mpdu1" "Hsap\MPDU1, Hsap\PQLC3" viable FBgn0266181 CRG CASK regulatory gene http://flybase.org/reports/FBgn0266181 non_protein_coding_gene - positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype - "CRG, CR44887" - CR44887 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,gravitaxis defective,locomotor behavior defective" FBgn0005397 Dia1 Diaphorase 1 http://flybase.org/reports/FBgn0005397 - gene dihydrolipoyl dehydrogenase activity ; GO:0004148 | inferred from direct assay - - "DIA-1, Dia1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065668 l(2)SH0692 lethal (2) SH0692 http://flybase.org/reports/FBgn0065668 gene - - - "l(2)SH0692, l(2)SH2 0692" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259422 C441 - http://flybase.org/reports/FBgn0259422 gene - - - C441 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing hair FBgn0085623 CG41337 - http://flybase.org/reports/FBgn0085623 protein_coding_gene - - - CG41337 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067345 l(3)B197 lethal (3) B197 http://flybase.org/reports/FBgn0067345 gene - - - l(3)B197 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024714 anon-57Cm anon-57Cm http://flybase.org/reports/FBgn0024714 - gene - - - anon-57Cm - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260782 5-103 - http://flybase.org/reports/FBgn0260782 gene - - - 5-103 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0002778 mnd minidiscs http://flybase.org/reports/FBgn0002778 "FBgn0002474, FBgn0004717" protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | traceable author statement L-amino acid transmembrane transporter activity ; GO:0015179 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 amino acid transmembrane transport ; GO:0003333 | inferred from electronic annotation with InterPro:IPR002293 amino acid transport ; GO:0006865 | traceable author statement leucine import ; GO:0060356 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 "mnd, SG29, l(3)ds-5, l(3)o52, md, l(3)ds5, l(3)SG29, l(3)B5, CG3297" IPR002293:Amino acid/polyamine transporter I CG3297 11-Aug-17 DroID_v2017_08 "Drer\slc7a8b, Drer\slc7a9, Drer\slc7a8a, Drer\slc7a14a, Drer\slc7a10b, Drer\zmp:0000001267, Drer\slc7a5, Drer\si:dkeyp-120h9.1, Drer\slc7a10a, Drer\slc7a6, Drer\si:ch73-352p4.8, Drer\slc7a7, Drer\slc7a11" "Scer\MUP1, Scer\TAT1, Scer\MMP1, Scer\BAP3, Scer\MUP3, Scer\GNP1" "Cele\aat-7, Cele\aat-4, Cele\aat-9, Cele\F23F1.6, Cele\B0454.6, Cele\aat-1, Cele\Y53F4B.12, Cele\aat-8, Cele\aat-5, Cele\aat-6, Cele\aat-2, Cele\aat-3" "Xtro\slc7a7, Xtro\slc7a13, Xtro\slc7a11, Xtro\slc7a9, Xtro\slc7a6, Xtro\LOC100492274, Xtro\slc7a10, Xtro\slc7a15, Xtro\slc7a5, Xtro\slc7a8" "Mmus\Slc7a11, Mmus\Slc7a5, Mmus\Slc7a8, Mmus\Slc7a6, Mmus\Slc7a13, Mmus\Slc7a9, Mmus\Slc7a10, Mmus\Slc7a14, Mmus\Slc7a7, Mmus\Slc7a12, Mmus\Slc7a15" "Hsap\SLC7A5, Hsap\SLC7A6, Hsap\SLC7A13, Hsap\SLC7A14, Hsap\SLC7A9, Hsap\SLC7A8, Hsap\SLC7A10, Hsap\SLC7A7, Hsap\SLC7A11" " embryonic stage , larval stage | first instar -- larval stage | second instar , larval stage | third instar , adult stage " " organism

, embryonic/larval fat body

" "viable,fertile,lethal,heat sensitive,lethal - all die before end of larval stage,recessive,some die during larval stage,cold sensitive,wild-type" "pupa,embryonic/larval brain,stage A1 adult,embryonic/larval fat body,imaginal disc,third instar larva,adult,embryo,eye-antennal disc,ventral thoracic disc,haltere disc,genital disc,larva,second instar larva" DRSC11370 I 0.208871109 -1.672097059 -0.602394188 -0.65190198 -0.390442967 -0.451043904 FBgn0035589 CHMP2B Charged multivesicular body protein 2b http://flybase.org/reports/FBgn0035589 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vacuolar transport ; GO:0007034 | inferred from electronic annotation with InterPro:IPR005024 endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with Vps2 ESCRT III complex ; GO:0000815 | inferred from sequence or structural similarity with SGD:S000001485 "CG4618, CHMP2B, cg4618" IPR005024:Snf7 family CG4618 11-Aug-17 DroID_v2017_08 "Drer\chmp1b, Drer\chmp2bb, Drer\chmp2ba" Scer\DID4 "Cele\C01A2.4, Cele\did-2" "Xtro\chmp1b, Xtro\chmp1a, Xtro\chmp2b" "Mmus\2610002M06Rik, Mmus\Chmp1a, Mmus\Chmp2b" "Hsap\CHMP1B, Hsap\CHMP1A, Hsap\CHMP2B" FBgn0267820 CR46145 - http://flybase.org/reports/FBgn0267820 non_protein_coding_gene - - - CR46145 - CR46145 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026645 l(2)k02503 lethal (2) k02503 http://flybase.org/reports/FBgn0026645 - gene - - - l(2)k02503 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263376 CR43428 - http://flybase.org/reports/FBgn0263376 non_protein_coding_gene - - - "CR43428, CG12865" - CR43428 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004926 eIF2beta eukaryotic translation initiation factor 2 subunit beta http://flybase.org/reports/FBgn0004926 FBgn0024970 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000006158 formation of translation preinitiation complex ; GO:0001731 | inferred from sequence or structural similarity with SGD:S000006158 response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype eukaryotic 43S preinitiation complex ; GO:0016282 | inferred from sequence or structural similarity with SGD:S000006158 microtubule associated complex ; GO:0005875 | inferred from direct assay multi-eIF complex ; GO:0043614 | inferred from sequence or structural similarity with SGD:S000006158 cytosol ; GO:0005829 | inferred from sequence or structural similarity eukaryotic translation initiation factor 2 complex ; GO:0005850 | inferred from sequence or structural similarity "CG4153, eIF2beta, D-eIF2beta, IF2B, elF2beta, eIF-2, eIF-2beta, Eif2beta" "IPR002735:Translation initiation factor IF2/IF5, IPR016189:Translation initiation factor IF2/IF5, N-terminal, IPR016190:Translation initiation factor IF2/IF5, zinc-binding" CG4153 11-Aug-17 DroID_v2017_08 Drer\eif2s2 Scer\SUI3 Cele\iftb-1 Xtro\slc5a8 Mmus\Eif2s2 Hsap\EIF2S2 embryonic stage -- adult stage "lethal,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "axon & pCC neuron,axon & pCC neuronED4486)" DRSC11341 EK -1.104901511 1.215548193 -1.221397396 -2.42423921 2.310376135 0.36974402 FBgn0259226 CG42326 - http://flybase.org/reports/FBgn0259226 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG14748, CG42326, CG14747" IPR003609:PAN/Apple domain CG42326 11-Aug-17 DroID_v2017_08 - - "Cele\ZC449.1, Cele\ZC449.2, Cele\cutl-27, Cele\H42K12.3, Cele\noah-1, Cele\F32B4.8, Cele\C34C12.7, Cele\T26C5.2, Cele\H03E18.1, Cele\cutl-18, Cele\let-653, Cele\T23F1.5, Cele\F52C9.5, Cele\cutl-17, Cele\C16D9.1, Cele\R07A4.4, Cele\noah-2" - - - FBgn0060659 l(3)SzB89Bb lethal (3) SzB89Bb http://flybase.org/reports/FBgn0060659 gene - - - "0826/09, l(3)S082609b, l(3)SzB89Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265172 T:TM-Sema-1a Transmembrane domain of Sema-1a http://flybase.org/reports/FBgn0265172 engineered_tag - - - T:TM-Sema-1a - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036893 PIG-F Phosphatidylinositol glycan anchor biosynthesis class F http://flybase.org/reports/FBgn0036893 protein_coding_gene - GPI anchor biosynthetic process ; GO:0006506 | inferred from electronic annotation with InterPro:IPR009580 endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR009580 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009580 "PIG-F, CG9376" IPR009580:GPI biosynthesis protein Pig-F CG9376 11-Aug-17 DroID_v2017_08 "Drer\kdsr, Drer\pigf" "Scer\TSC10, Scer\GPI11" "Cele\str-40, Cele\str-28" Xtro\pigf "Mmus\Kdsr, Mmus\Pigf" "Hsap\PIGF, Hsap\KDSR" viable FBgn0262847 CR43211 - http://flybase.org/reports/FBgn0262847 pseudogene_attribute - - - CR43211 - CR43211 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067637 106y 106y http://flybase.org/reports/FBgn0067637 gene - - - 106y - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0022363 Pt-9 Larval protein-9 http://flybase.org/reports/FBgn0022363 - gene - - - "PT-9, Pt-9" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019689 l(3)92Eb lethal (3) 92Eb http://flybase.org/reports/FBgn0019689 - gene - - - "HSH11, l(3)92Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,recessive" FBgn0264494 CG17646 - http://flybase.org/reports/FBgn0264494 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" triglyceride metabolic process ; GO:0006641 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CG17646, l(2)SH0142, l(2)SH2 0142, ABCG1, BEST:GH05015, CG17647" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR017871:ABC transporter, conserved site" CG17646 11-Aug-17 DroID_v2017_08 "Drer\abcg1, Drer\abcg4b, Drer\abcg8, Drer\abcg5, Drer\abcg4a, Drer\abcg2b, Drer\abcg2a" "Scer\YOL075C, Scer\PDR10, Scer\PDR12, Scer\ADP1, Scer\PDR18" "Cele\abch-1, Cele\wht-1, Cele\wht-4" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg8, Mmus\Abcg5, Mmus\Abcg1, Mmus\Abcg2, Mmus\Abcg3, Mmus\Abcg4" "Hsap\ABCG1, Hsap\ABCG4, Hsap\ABCG5, Hsap\ABCG8" FBgn0033798 CG15870 - http://flybase.org/reports/FBgn0033798 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15870 - CG15870 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034391 CG15080 - http://flybase.org/reports/FBgn0034391 protein_coding_gene - - - CG15080 - CG15080 11-Aug-17 DroID_v2017_08 "Drer\tgfbi, Drer\postnb, Drer\postna" Scer\YLR001C Cele\F26E4.7 - "Mmus\Tgfbi, Mmus\Postn" "Hsap\POSTN, Hsap\TGFBI" FBgn0086686 l(3)L1231 lethal (3) L1231 http://flybase.org/reports/FBgn0086686 protein_coding_gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001044713 "LD14744, BEST:LD14744, CG7832, l(3)L1231" IPR025927:Potential DNA-binding domain CG7832 11-Aug-17 DroID_v2017_08 "Drer\kansl2, Drer\ino80db" - "Cele\Y49E10.29, Cele\sumv-1, Cele\ins-33" Xtro\kansl2 "Mmus\Ino80d, Mmus\Kansl2" Hsap\INO80D FBgn0061112 l(3)SzB90Ce lethal (3) SzB90Ce http://flybase.org/reports/FBgn0061112 gene - - - "0065/17, l(3)S006517b, l(3)SzB90Ce" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060798 l(3)S057706b lethal (3) S057706b http://flybase.org/reports/FBgn0060798 gene - - - "0577/06, l(3)S057706b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0027144 l(3)71DEc lethal (3) 71DEc http://flybase.org/reports/FBgn0027144 - gene - - - "1(3)71DEc, l(3)71DEc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084039 CG41479 - http://flybase.org/reports/FBgn0084039 protein_coding_gene - - - CG41479 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067675 nansen nansen http://flybase.org/reports/FBgn0067675 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "nan, nansen" - - 11-Aug-17 DroID_v2017_08 - - - - - - "oocyte,germline clone,oocyte nucleus" FBgn0066350 l(3)99DEe lethal (3) 99DEe http://flybase.org/reports/FBgn0066350 gene - - - l(3)99DEe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031749 CG14000 - http://flybase.org/reports/FBgn0031749 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14000 - CG14000 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0011636 l(2)T57h9 lethal (2) T57h9 http://flybase.org/reports/FBgn0011636 FBgn0005177 gene - - - l(2)T57h9 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003876 tu(2)48 tumor(2)48 http://flybase.org/reports/FBgn0003876 - gene - - - "tu-48a, tu(2)48" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,viable,fertile" FBgn0001097 Gull Gulloid http://flybase.org/reports/FBgn0001097 - gene - - - "Gd, Gull" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" wing FBgn0005713 l(1)TK116 lethal (1) TK116 http://flybase.org/reports/FBgn0005713 - gene - - - "l116, l(1)TK116" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036913 Usp32 Ubiquitin specific protease 32 http://flybase.org/reports/FBgn0036913 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from electronic annotation with InterPro:IPR006615 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:12629 cellular_component ; GO:0005575 | no biological data available "USP15, Usp32, CG8334, Q9VW49, usp32" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR002048:EF-hand domain, IPR006615:Peptidase C19, ubiquitin-specific peptidase, DUSP domain, IPR011992:EF-hand domain pair, IPR018200:Ubiquitin specific protease, conserved site, IPR018247:EF-Hand 1, calcium-binding site, IPR028889:Ubiquitin specific protease domain" CG8334 11-Aug-17 DroID_v2017_08 "Drer\usp43a, Drer\usp32, Drer\usp2a, Drer\usp11, Drer\usp4, Drer\usp31, Drer\usp20, Drer\usp43b, Drer\usp8, Drer\usp33, Drer\usp19" "Scer\UBP12, Scer\UBP5, Scer\UBP8" "Cele\Y67D2.2, Cele\cyk-3, Cele\usp-50, Cele\F07A11.4, Cele\usp-3, Cele\usp-33, Cele\H34C03.2" "Xtro\usp19, Xtro\usp31, Xtro\usp33, Xtro\usp32, Xtro\usp15, Xtro\usp20, Xtro\usp4" "Mmus\Usp11, Mmus\Usp15, Mmus\Usp32, Mmus\Usp2, Mmus\Usp19, Mmus\Usp27x, Mmus\Usp4, Mmus\Usp43, Mmus\Usp22, Mmus\Usp31, Mmus\Usp3, Mmus\Usp8, Mmus\Usp20, Mmus\Usp33, Mmus\Usp39" "Hsap\USP2, Hsap\TBC1D3G, Hsap\USP8, Hsap\USP32, Hsap\USP22, Hsap\USP15, Hsap\USP3, Hsap\USP19, Hsap\USP11, Hsap\USP20, Hsap\TBC1D3H, Hsap\TBC1D3B, Hsap\USP39, Hsap\TBC1D3, Hsap\USP31, Hsap\USP43, Hsap\USP27X, Hsap\TBC1D3C, Hsap\TBC1D3F, Hsap\USP6, Hsap\USP4" viable FBgn0266240 CR44935 - http://flybase.org/reports/FBgn0266240 non_protein_coding_gene - - - "CR44935, lincRNA.716" - CR44935 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002635 mab malformed abdomen http://flybase.org/reports/FBgn0002635 - gene - - - "Ebmab, Ecmab, mab" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal,heat sensitive" "abdomen,heat sensitive,cuticle" FBgn0013321 Pcp8 Pupal-cuticle-protein-8kD http://flybase.org/reports/FBgn0013321 - gene - - - Pcp8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040945 CG12639 - http://flybase.org/reports/FBgn0040945 protein_coding_gene - - - CG12639 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016843 l(1)N17 lethal (1) N17 http://flybase.org/reports/FBgn0016843 - gene - - - "l(1)N17, N17" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027122 l(?)5A lethal (?) 5A http://flybase.org/reports/FBgn0027122 - gene - - - l(?)5A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032249 TBC1D16 TBC1 domain family member 16 http://flybase.org/reports/FBgn0032249 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 "CG5337, TBC1D16" IPR000195:Rab-GTPase-TBC domain CG5337 11-Aug-17 DroID_v2017_08 Drer\tbc1d16 Scer\GYP7 Cele\tbc-16 Xtro\tbc1d16 Mmus\Tbc1d16 Hsap\TBC1D16 viable FBgn0264383 CR43835 - http://flybase.org/reports/FBgn0264383 non_protein_coding_gene - - - "CR43835, lincRNA.961" - CR43835 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083095 cbe celibe http://flybase.org/reports/FBgn0083095 gene - meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype - cbe - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,cytokinesis defective" "spermatid & nucleus | supernumerary,Nebenkern,spindle & meiotic cell cycle | male,contractile ring & meiotic cell cycle | male" FBgn0016700 Rab1 Rab1 http://flybase.org/reports/FBgn0016700 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity" carbohydrate homeostasis ; GO:0033500 | inferred from mutant phenotype positive regulation of insulin secretion ; GO:0032024 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 actin filament organization ; GO:0007015 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of cell migration ; GO:0030334 | inferred from mutant phenotype anterograde axonal transport ; GO:0008089 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | traceable author statement cell adhesion ; GO:0007155 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 neuronal cell body ; GO:0043025 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000634841 cytoplasm ; GO:0005737 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000634841 "Rab1, Dm Rab1, AAF55873, DmRab1, drab1, CG3320, dRab1, rab1, DRab1, DRAB1, dar6, RAB1a, Rab1a, O18332" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3320 11-Aug-17 DroID_v2017_08 "Drer\rab8a, Drer\rab1bb, Drer\rabl6a, Drer\rab10, Drer\rab1ba, Drer\si:dkey-16l2.16, Drer\rab35b, Drer\rab19, Drer\rabl6b, Drer\rab1ab, Drer\zgc:101559, Drer\rab33a, Drer\zgc:171927, Drer\rab13, Drer\rab33ba, Drer\rab8b, Drer\rab43, Drer\rab1aa" Scer\YPT1 "Cele\rab-1, Cele\rab-35, Cele\rab-8" "Xtro\rab8b, Xtro\rab1a, Xtro\rabl6, Xtro\rab33a, Xtro\rab35, Xtro\rab35, Xtro\rab13, Xtro\rab8a, Xtro\rab33b, Xtro\rab19" "Mmus\Rab35, Mmus\Rab33b, Mmus\Rab8b, Mmus\Rab33a, Mmus\Rab19, Mmus\Rab13, Mmus\Rab43, Mmus\Rab10, Mmus\Rab8a, Mmus\Rab1b, Mmus\Rab1a, Mmus\Rabl6" "Hsap\RAB33A, Hsap\RAB43, Hsap\RAB1A, Hsap\RAB1B, Hsap\RAB33B, Hsap\RAB13, Hsap\RAB8B, Hsap\RABL6, Hsap\RAB35, Hsap\RAB10" "lethal,neuroanatomy defective,female sterile,germline clone,recessive,cell lethal,body size defective,developmental rate defective" "dendrite & dendritic arborising neuron,Golgi apparatus & photoreceptor cellhs.PB,rough endoplasmic reticulum & photoreceptor cellhs.PB,microvillus & photoreceptor cellhs.PB,larval dorsomedial neurosecretory cell,dendriteIlp2.PW" DRSC29851 K -0.349198566 0.527084484 0.697887987 -1.087054899 -1.295831944 -1.524727707 FBgn0004175 Mst84Dd Male-specific RNA 84Dd http://flybase.org/reports/FBgn0004175 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available "sperm axoneme assembly ; GO:0007288 | inferred from genetic interaction with Mst84Da, Mst84Db, Mst84Dc spermatogenesis ; GO:0007283 | inferred from genetic interaction with Mst84Da, Mst84Db, Mst84Dc" cellular_component ; GO:0005575 | no biological data available "Mst, Mstprox, Mst ORF, Mst84, Mst87D, mst(3)gl-4, CG17935, Mst84Dd" IPR005634:Male specific sperm protein CG17935 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014019 Rh5 Rhodopsin 5 http://flybase.org/reports/FBgn0014019 - protein_coding_gene G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity G-protein coupled photoreceptor activity ; GO:0008020 | inferred from genetic interaction with ninaE G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with ninaE inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4 G-protein coupled photoreceptor activity ; GO:0008020 | non-traceable author statement G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4 inferred from sequence or structural similarity with protein_id:CAA56378.1 "visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR000856 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000856 thermotaxis ; GO:0043052 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4 inferred from sequence or structural similarity with protein_id:CAA56378.1 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity sensory perception of sound ; GO:0007605 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from sequence or structural similarity with ninaE inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4 inferred from genetic interaction with ninaE phototransduction ; GO:0007602 | non-traceable author statement response to light stimulus ; GO:0009416 | inferred from direct assay absorption of visible light ; GO:0016038 | inferred from mutant phenotype entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from genetic interaction with Rh6, cry inferred from genetic interaction with Rh6, cry, norpA inferred from genetic interaction with cry, norpA phototransduction ; GO:0007602 | inferred from genetic interaction with ninaE UV-A, blue light phototransduction ; GO:0009588 | non-traceable author statement" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with ninaE inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4 rhabdomere ; GO:0016028 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4 inferred from sequence or structural similarity with protein_id:CAA56378.1 "rh5, Rh, RH5, DMELRH5, Dm Rh5, CG5279, Rh5" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000856:Opsin RH3/RH4, IPR017452:GPCR, rhodopsin-like, 7TM, IPR027430:Visual pigments (opsins) retinal binding site" CG5279 11-Aug-17 DroID_v2017_08 "Drer\rgrb, Drer\rrh, Drer\opn8b, Drer\rgra, Drer\rho, Drer\opn1mw3, Drer\valopa, Drer\rhol, Drer\opn1lw2, Drer\opn6a, Drer\opn8c, Drer\tmtops3a, Drer\opn1mw1, Drer\tmtops3b, Drer\opn3, Drer\parietopsin, Drer\opn9, Drer\opn4b, Drer\opn6b, Drer\tmtopsb, Drer\exorh, Drer\valopb, Drer\opn7c, Drer\tmtops2a, Drer\opn1sw1, Drer\opn7a, Drer\opn1sw2, Drer\opn1mw4, Drer\opn7d, Drer\opn4.1, Drer\opn1lw1, Drer\parapinopsinb, Drer\opn4xb, Drer\opn4a, Drer\tmtops2b, Drer\opn7b, Drer\opn5, Drer\opn4xa" - "Cele\sro-1, Cele\nmur-3" "Xtro\rrh, Xtro\tmtops.2, Xtro\LOC100485989, Xtro\rho, Xtro\LOC100124934, Xtro\opn1sw, Xtro\tmtops, Xtro\LOC100485437, Xtro\opn1lw, Xtro\opn5" "Mmus\Opn3, Mmus\Opn4, Mmus\Opn1mw, Mmus\Rho, Mmus\Rgr, Mmus\Opn5, Mmus\Rrh, Mmus\Opn1sw, Mmus\Olfr109" "Hsap\OR12D3, Hsap\RHO, Hsap\OPN1MW, Hsap\OPN4, Hsap\OPN1MW3, Hsap\RGR, Hsap\RRH, Hsap\OPN1MW2, Hsap\OPN5, Hsap\OPN1SW, Hsap\OPN3, Hsap\OPN1LW" adult stage " adult head

, photoreceptor cell R8

" adult stage photoreceptor cell R8

"phototaxis defective,auditory perception defective,neurophysiology defective,visual behavior defective" eye photoreceptor cell FBgn0028410 Pk34A Pk34A http://flybase.org/reports/FBgn0028410 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 "GSK3a, CG5182, Pk34A" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG5182 11-Aug-17 DroID_v2017_08 "Drer\gsk3ab, Drer\gsk3b, Drer\gsk3aa, Drer\si:dkeyp-80c12.7" "Scer\RIM11, Scer\MRK1, Scer\YGK3, Scer\MCK1" "Cele\gska-3, Cele\gsk-3, Cele\F21F3.2, Cele\Y106G6E.1, Cele\C44H4.6, Cele\R03D7.5, Cele\Y106G6D.4, Cele\cdc-7" "Xtro\gsk3a, Xtro\gsk3b" "Mmus\Gsk3b, Mmus\Cdkl3, Mmus\Gsk3a, Mmus\Cdkl2" "Hsap\CDKL3, Hsap\GSK3A, Hsap\GSK3B, Hsap\CDKL2" viable FBgn0051960 CG31960 - http://flybase.org/reports/FBgn0051960 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "CG10022, CG31960, CBP1" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG31960 11-Aug-17 DroID_v2017_08 "Drer\efcab11, Drer\calml4b, Drer\caln1, Drer\cabp5b, Drer\pvalb2, Drer\pvalb9, Drer\cabp1b, Drer\calm3b, Drer\calb2a, Drer\caln2, Drer\cabp2a, Drer\efcab2, Drer\cabp5a, Drer\calm2a, Drer\cabp1a, Drer\pvalb4, Drer\pvalb3, Drer\calb2b, Drer\calm3a, Drer\scgn, Drer\calm1b, Drer\pvalb8, Drer\rhbdl3, Drer\tnnc1a, Drer\tnnc2, Drer\calm1a, Drer\calm2b, Drer\cabp4, Drer\calb1, Drer\pvalb1, Drer\si:ch211-197n1.2, Drer\calml4a, Drer\efcab6, Drer\pvalb6, Drer\tnnc1b, Drer\cabp7b, Drer\cabp2b" "Scer\CMD1, Scer\MLC1, Scer\MLC2" "Cele\tnc-2, Cele\cal-1, Cele\cal-2, Cele\cmd-1, Cele\cal-4, Cele\cal-3" "Xtro\pvalb.2, Xtro\calm2, Xtro\pgm1, Xtro\pvalb.1, Xtro\calb1, Xtro\LOC548651, Xtro\ocm, Xtro\tnnc1, Xtro\calml4, Xtro\scgn, Xtro\pvalb, Xtro\cabp7, Xtro\cabp4, Xtro\ocm.2, Xtro\calm1, Xtro\efcab6, Xtro\tnnc2" "Mmus\Calm1, Mmus\Caln1, Mmus\Ocm, Mmus\1700023F06Rik, Mmus\Calm5, Mmus\Calm2, Mmus\Efcab2, Mmus\Calm4, Mmus\Tnnc2, Mmus\Cabp5, Mmus\Pvalb, Mmus\Cabp7, Mmus\Cabp4, Mmus\Efcab9, Mmus\Cabp1, Mmus\Cabp2, Mmus\Calm3, Mmus\Scgn, Mmus\Efcab11, Mmus\Efcab6, Mmus\Calml3, Mmus\Spata21, Mmus\Efcab7, Mmus\Calb2, Mmus\Rhbdl3, Mmus\Tnnc1, Mmus\Efcab3, Mmus\Calb1, Mmus\Calml4" "Hsap\EFCAB13, Hsap\CALML6, Hsap\SPATA21, Hsap\CALML5, Hsap\CABP4, Hsap\CALB1, Hsap\EFCAB11, Hsap\PVALB, Hsap\CALM1, Hsap\CABP7, Hsap\OCM, Hsap\CALML3, Hsap\CALM2, Hsap\CALN1, Hsap\CALB2, Hsap\CABP2, Hsap\TNNC1, Hsap\EFCAB2, Hsap\C2orf61, Hsap\CALML4, Hsap\RHBDL3, Hsap\CABP5, Hsap\EFCAB6, Hsap\OCM2, Hsap\CALM3, Hsap\EFCAB7, Hsap\SCGN, Hsap\CABP1, Hsap\EFCAB3, Hsap\TNNC2, Hsap\EFCAB9" FBgn0037525 CG17816 - http://flybase.org/reports/FBgn0037525 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR029136 negative regulation of centriole replication ; GO:0046600 | inferred from electronic annotation with InterPro:IPR029136 - CG17816 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical, IPR029136:Nuclear protein MDM1" CG17816 11-Aug-17 DroID_v2017_08 - - - - - - DRSC15277 I -0.312071859 -1.533154081 0.267109373 -0.640753046 0.106762644 0.008576105 FBgn0262857 CG43221 - http://flybase.org/reports/FBgn0262857 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43221, DMG8-chr2L.31.003" - CG43221 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086677 jeb jelly belly http://flybase.org/reports/FBgn0086677 protein_coding_gene transmembrane receptor protein tyrosine kinase activator activity ; GO:0030297 | inferred from direct assay salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype positive regulation of MAPK cascade ; GO:0043410 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from mutant phenotype muscle cell fate specification ; GO:0042694 | inferred from mutant phenotype visceral muscle development ; GO:0007522 | inferred from mutant phenotype positive regulation of MAPK cascade ; GO:0043410 | inferred from direct assay synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | traceable author statement compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay extracellular region ; GO:0005576 | traceable author statement terminal bouton ; GO:0043195 | inferred from direct assay type Ib terminal bouton ; GO:0061176 | inferred from direct assay type Is terminal bouton ; GO:0061177 | inferred from direct assay cell surface ; GO:0009986 | "jeb, l(2)k05644, CG13182, CG13180, CG30040, l(2)SH0422, Jeb" "IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site" CG30040 11-Aug-17 DroID_v2017_08 - - "Cele\T14E8.2, Cele\hen-1" - - - FBgn0011239 ms(2)35Ci male sterile (2) 35Ci http://flybase.org/reports/FBgn0011239 "FBgn0045996, FBgn0051733, FBgn0063291" protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatid differentiation ; GO:0048515 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "ms(2)46AB, NEST:bs29a09, ms(2)02316, CG31733, BcDNA:AT28918, ms(2)35Ci" - CG31733 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,male fertile,partially lethal - majority die,viable" FBgn0032685 CG10211 - http://flybase.org/reports/FBgn0032685 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 - CG10211 "IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal" CG10211 11-Aug-17 DroID_v2017_08 "Drer\ptgs1, Drer\ptgs2b, Drer\tpo, Drer\ptgs2a, Drer\igsf9bb" - "Cele\K10B4.1, Cele\C46A5.4, Cele\F09F3.5, Cele\R08F11.7, Cele\T06D8.10" "Xtro\epx, Xtro\mpo, Xtro\ptgs1, Xtro\pxdn, Xtro\ptgs2, Xtro\tpo" "Mmus\Lpo, Mmus\Epx, Mmus\Pxdn, Mmus\Ptgs1, Mmus\Mpo, Mmus\Tpo, Mmus\Ptgs2" "Hsap\PXDN, Hsap\PTGS2, Hsap\PTGS1, Hsap\LPO, Hsap\TPO, Hsap\EPX, Hsap\PXDNL, Hsap\MPO" lethal DRSC02027 IE -0.234617269 -1.609864547 1.011576503 1.900762961 -0.502999389 -1.036015335 FBgn0264079 T:Myr-Src64B Myristoylation sequence of Src64B http://flybase.org/reports/FBgn0264079 engineered_tag - - - "T:Myr-Src64B, T:Myr1, T:Src64B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003046 Pcp Pupal cuticle protein http://flybase.org/reports/FBgn0003046 - protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of pupal chitin-based cuticle ; GO:0008011 | traceable author statement structural constituent of pupal chitin-based cuticle ; GO:0008011 | inferred from sequence or structural similarity with Lcp1 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "DMCPGART, Gart, Pcpgart, CG3440, Pcp, DmelPcp" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG3440 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\math-34, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " pupal stage , larval stage | third instar , prepupal stage , prepupal stage | stage P4 " epidermis &&of larval abdomen

"partially lethal - majority die,some die during pupal stage" FBgn0263866 CR43713 - http://flybase.org/reports/FBgn0263866 non_protein_coding_gene - - - "CR43713, lincRNA.47" - CR43713 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051896 tRNA:Asp-GTC-1-2 transfer RNA:Aspartic acid-GTC 1-2 http://flybase.org/reports/FBgn0051896 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "AE002690.trna4-AspGTC, tRNA:asp2:29D, tRNA:D2:29D, tRNA:D:GTC:AE002690-a, CR31896, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna12-AspGTC, tRNA:Asp-GTC-1-2, tRNA:CR31896, tRNA-Asp-GTC-1-2, GAC" - CR31896 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265877 CR44666 - http://flybase.org/reports/FBgn0265877 non_protein_coding_gene - - - CR44666 - CR44666 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037234 CG9795 - http://flybase.org/reports/FBgn0037234 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9795 IPR015943:WD40/YVTN repeat-like-containing domain CG9795 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004674 dv2 divergent 2 http://flybase.org/reports/FBgn0004674 - gene - - - dv2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0060623 l(3)S087902 lethal (3) S087902 http://flybase.org/reports/FBgn0060623 gene - - - "0879/02, l(3)S087902" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0259175 ome omega http://flybase.org/reports/FBgn0259175 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR001375 dipeptidyl-peptidase activity ; GO:0008239 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay - "CG32145, CG42280, LD21715, CG9370, CG17705, BEST:LD21715, ome, CG32143, Ome" "IPR002469:Dipeptidylpeptidase IV, N-terminal domain, IPR029058:Alpha/Beta hydrolase fold, IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain" CG42280 11-Aug-17 DroID_v2017_08 "Drer\fap, Drer\zgc:136971, Drer\apeh, Drer\LOC101886435, Drer\dpp4, Drer\dpp6b, Drer\dpp6a, Drer\LOC101883320, Drer\actc1b" "Scer\DAP2, Scer\STE13" "Cele\dpf-1, Cele\dpf-2" "Xtro\dpp10, Xtro\dpp4, Xtro\dpp6, Xtro\fap, Xtro\apeh" "Mmus\Dpp6, Mmus\Fap, Mmus\Dpp4, Mmus\Apeh, Mmus\Dpp10" "Hsap\DPP10, Hsap\DPP4, Hsap\DPP6, Hsap\FAP, Hsap\APEH" FBgn0053471 Ir48a Ionotropic receptor 48a http://flybase.org/reports/FBgn0053471 pseudogene_attribute - - - "DmelIR48a, CR33471, Ir48a, IR48a" - CR33471 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036520 CG13449 - http://flybase.org/reports/FBgn0036520 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13449 - CG13449 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011335 vers versatile http://flybase.org/reports/FBgn0011335 FBgn0036247 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(3)jD3, l(3)68Fb, CG6801, l(3)j2D3, L(3)JD3, vers" IPR026095:Myb/SANT-like DNA-binding domain-containing protein CG6801 11-Aug-17 DroID_v2017_08 Drer\msantd1 - - - Mmus\Msantd1 Hsap\MSANTD1 "lethal,recessive" FBgn0034809 CG13542 - http://flybase.org/reports/FBgn0034809 protein_coding_gene - - - CG13542 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028100 l(3)S072703b lethal (3) S072703b http://flybase.org/reports/FBgn0028100 gene - - - "0727/03, l(3)S072703, l(3)S072703b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051723 CG31723 - http://flybase.org/reports/FBgn0051723 protein_coding_gene - - - CG31723 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC01141 K -0.910762608 -0.595567164 0.493725798 0.551923352 0.657179906 2.539360443 FBgn0069159 mcl(3)Z2094 mcl(3)Z2094 http://flybase.org/reports/FBgn0069159 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z2094 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0035983 CG4080 - http://flybase.org/reports/FBgn0035983 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:26077 chaeta development ; GO:0022416 | inferred from genetic interaction with Chi wing disc development ; GO:0035220 | inferred from genetic interaction with Bx protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:26077 late endosome membrane ; GO:0031902 | inferred from sequence or structural similarity with HGNC:26077 early endosome membrane ; GO:0031901 | inferred from sequence or structural similarity with HGNC:26077 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:26077 "CG4080, 4080" "IPR011016:Zinc finger, RING-CH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033275:E3 ubiquitin-protein ligase MARCH-like" CG4080 11-Aug-17 DroID_v2017_08 "Drer\march1, Drer\march9, Drer\march7, Drer\zgc:153256, Drer\zgc:158785, Drer\march2, Drer\march11, Drer\march8, Drer\march4, Drer\march6" Scer\SSM4 "Cele\marc-1, Cele\marc-4, Cele\marc-5, Cele\marc-3, Cele\marc-2, Cele\marc-6" "Xtro\march4, Xtro\march3, Xtro\march8, Xtro\march7, Xtro\march2, Xtro\march1, Xtro\march9, Xtro\march11" "Mmus\March4, Mmus\March2, Mmus\March3, Mmus\March1, Mmus\March9, Mmus\March11, Mmus\March6, Mmus\March10, Mmus\March8" "Hsap\MARCH2, Hsap\MARCH9, Hsap\MARCH8, Hsap\MARCH6, Hsap\MARCH11, Hsap\MARCH4, Hsap\MARCH3, Hsap\MARCH10, Hsap\MARCH1, Hsap\MARCH7" viable FBgn0283468 slmb supernumerary limbs http://flybase.org/reports/FBgn0283468 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR021977 phosphoprotein binding ; GO:0051219 | inferred from physical interaction with ci ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with HGNC:1144 negative regulation of Wnt signaling pathway ; GO:0030178 | non-traceable author statement <> negative regulation of apoptotic process ; GO:0043066 |... mutant phenotype <> chorion-containing eggshell formation ; GO:0007304 |... mutant phenotype <> ovarian follicle cell development ; GO:0030707 |... mutant phenotype <> proteolysis ; GO:0006508 |... mutant phenotype <> release of cytoplasmic sequestered NF-kappaB ; GO:0008588 |... mutant phenotype <> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | non-traceable author statement <> regulation of centriole replication ; GO:0046599 |... direct assay <> negative regulation of Wnt signaling pathway ; GO:0030178 |... mutant phenotype <> locomotor rhythm ; GO:0045475 |... mutant phenotype <> regulation of Wnt signaling pathway ; GO:0030111 |... mutant phenotype <> negative regulation of cell proliferation ; GO:0008285 |... mutant phenotype <> oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 |... mutant phenotype <> negative regulation of nurse cell apoptotic process ; GO:0045849 |... mutant phenotype <> regulation of Wnt signaling pathway ; GO:0030111 | traceable author statement <> release of cytoplasmic sequestered NF-kappaB ; GO:0008588 | traceable author statement <> negative regulation of insulin receptor signaling pathway ; GO:0046627 |... genetic interaction with InR <> negative regulation of glial cell proliferation ; GO:0060253 |... genetic interaction with ago <> neuron remodeling ; GO:0016322 |... mutant phenotype <> negative regulation of TOR signaling ; GO:0032007 |... physical interaction with Akt1 <> germarium-derived female germ-line cyst formation ; GO:0030727 |... mutant phenotype <> border follicle cell migration ; GO:0007298 |... mutant phenotype <> regulation of proteolysis ; GO:0030162 | traceable author statement <> protein ubiquitination ; GO:0016567 |... mutant phenotype <> SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 |... biological aspect of ancestor with PANTHER:PTN001108256 <> establishment of epithelial cell polarity ; GO:0090162 |... mutant phenotype <> regulation of chromosome condensation ; GO:0060623 |... mutant phenotype <> SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 |... sequence model <> germarium-derived egg chamber formation ; GO:0007293 |... mutant phenotype <> dorsal appendage formation ; GO:0046843 |... mutant phenotype <> negative regulation of smoothened signaling pathway ; GO:0045879 |... mutant phenotype <> regulation of mitotic nuclear division ; GO:0007088 |... mutant phenotype <> pole plasm oskar mRNA localization ; GO:0045451 |... mutant phenotype <> learning or memory ; GO:0007611 |... mutant phenotype <> olfactory learning ; GO:0008355 |... mutant phenotype <> germarium-derived female germ-line cyst encapsulation ; GO:0030708 |... mutant phenotype <> regulation of smoothened signaling pathway ; GO:0008589 | traceable author statement <> regulation of establishment of cell polarity ; GO:2000114 |... mutant phenotype <> oocyte axis specification ; GO:0007309 |... mutant phenotype <> circadian rhythm ; GO:0007623 |... mutant phenotype inferred from physical interaction with dco inferred from physical interaction with per <> ovarian follicle cell stalk formation ; GO:0030713 |... mutant phenotype SCF ubiquitin ligase complex ; GO:0019005 | non-traceable author statement SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay ubiquitin ligase complex ; GO:0000151 | inferred from sequence or structural similarity SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | traceable author statement "MENE(3R)-B, MENE (3R)-B, Slimb, Slmb, Slimb/betaTrCP, slmb, slimb, SLMB, CG3412, ica, shv, l(3)00295, crd, BcDNA:GM02031, Slimb/Beta-TRCP1, Slimb/beta-TRCP, FBXW1, wel, SLIMB, betaTrCP" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR020472:G-protein beta WD-40 repeat, IPR001680:WD40 repeat, IPR001810:F-box domain, IPR019775:WD40 repeat, conserved site, IPR021977:D domain of beta-TrCP" CG3412 11-Aug-17 DroID_v2017_08 "Drer\daw1, Drer\fbxw7, Drer\fbxw11b, Drer\fbxw11a" "Scer\MDV1, Scer\CDC4, Scer\CAF4, Scer\MET30" "Cele\sel-10, Cele\lin-23" "Xtro\daw1, Xtro\fbxw7, Xtro\btrc" "Mmus\Btrc, Mmus\Fbxw7, Mmus\Daw1, Mmus\Fbxw11" "Hsap\FBXW7, Hsap\DAW1, Hsap\WDR64, Hsap\BTRC, Hsap\FBXW11" DRSC17056 K 0.177495942 0.401581989 -0.530153156 -0.969514645 0.821495136 2.735595372 FBgn0027495 Smyd4-4 "SET and MYND domain containing, class 4, member 4" http://flybase.org/reports/FBgn0027495 - protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "BcDNA:LD29892, Smyd4-4, CG8378" "IPR001214:SET domain, IPR002893:Zinc finger, MYND-type, IPR011990:Tetratricopeptide-like helical domain" CG8378 11-Aug-17 DroID_v2017_08 "Drer\smyd4, Drer\smyd2b, Drer\smyd1b, Drer\smyd2a, Drer\smyd1a, Drer\smyd3" "Scer\SET5, Scer\SET6" Cele\set-3 "Xtro\smyd1, Xtro\smyd4, Xtro\smyd5" "Mmus\Smyd1, Mmus\Smyd3, Mmus\Zmynd15, Mmus\Smyd5, Mmus\Smyd2, Mmus\Smyd4" "Hsap\SMYD4, Hsap\SMYD5, Hsap\SMYD1, Hsap\SMYD3, Hsap\SMYD2, Hsap\ZMYND15" viable FBgn0086540 MRE8 mRNA-like ncRNA in embryogenesis 8 http://flybase.org/reports/FBgn0086540 non_protein_coding_gene - - - "MRE8, GM07040" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050091 CG30091 - http://flybase.org/reports/FBgn0050091 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "CG8212, CG30091" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site" CG30091 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.12, Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.9, Drer\LOC558805, Drer\zgc:165423, Drer\gzm3, Drer\si:dkey-21e2.7, Drer\si:dkey-21e2.15" - Cele\try-3 Xtro\prss8 "Mmus\Gzmd, Mmus\Gzmb, Mmus\Gzmg, Mmus\Gzme, Mmus\Mcpt1, Mmus\Mcpt8, Mmus\Cma1, Mmus\Mcpt4, Mmus\Egfbp2, Mmus\Cma2, Mmus\Prss53, Mmus\Ctsg, Mmus\Mcpt9, Mmus\Gzmf, Mmus\Klk6, Mmus\Gzmc" "Hsap\CMA1, Hsap\CTSG, Hsap\GZMB, Hsap\PRSS54, Hsap\GZMH" viable FBgn0264382 CR43834 - http://flybase.org/reports/FBgn0264382 non_protein_coding_gene - - - CR43834 - CR43834 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264677 CR43962 - http://flybase.org/reports/FBgn0264677 non_protein_coding_gene - - - "CR43962, lincRNA.1044" - CR43962 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029176 eEF1gamma eukaryotic translation elongation factor 1 gamma http://flybase.org/reports/FBgn0029176 protein_coding_gene translation elongation factor activity ; GO:0003746 | inferred from electronic annotation with InterPro:IPR001662 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity translational elongation ; GO:0006414 | inferred from electronic annotation with InterPro:IPR001662 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern translational elongation ; GO:0006414 | inferred from sequence or structural similarity lipid particle ; GO:0005811 | inferred from direct assay eukaryotic translation elongation factor 1 complex ; GO:0005853 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "EF1gamma, Ef1Bggr, CG11901, Ef1gamma, eEF1gamma, Ef1y, EF1 gamma" "IPR001662:Translation elongation factor EF1B, gamma chain, conserved, IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG11901 11-Aug-17 DroID_v2017_08 "Drer\zgc:163074, Drer\gstt1a, Drer\vars, Drer\eef1e1, Drer\gstr, Drer\gstt2, Drer\gstt1b, Drer\eef1g, Drer\mars" "Scer\TEF4, Scer\YGR201C, Scer\GTT1, Scer\GTT2, Scer\URE2, Scer\CAM1" Cele\eef-1G "Xtro\eef1g, Xtro\gstt1, Xtro\eef1e1" "Mmus\Gstt4, Mmus\Gstt1, Mmus\Gstt3, Mmus\Mars, Mmus\Eef1e1, Mmus\Eef1g, Mmus\Vars, Mmus\Gstt2" "Hsap\GSTT2, Hsap\GSTT2B, Hsap\VARS, Hsap\EEF1E1, Hsap\MARS, Hsap\GSTT1, Hsap\EEF1G" "viable,visible,recessive,lethal,wild-type,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during larval stage,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,posterior compartment,eye,scutellar bristle,ectopic,somatic clone,ommatidium" DRSC16659 E 0.361479745 -0.722863215 2.169333932 -0.676437615 0.289683414 0.30027874 FBgn0263214 CR43384 - http://flybase.org/reports/FBgn0263214 pseudogene_attribute - - - CR43384 - CR43384 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001499 l(1)10Bm lethal (1) 10Bm http://flybase.org/reports/FBgn0001499 - gene - - - "l(1)L9, 9, l9, l(1)10Bm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0043347 EP3707 EP3707 http://flybase.org/reports/FBgn0043347 gene - - - EP3707 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible macrochaeta FBgn0005513 l(2)25Cg lethal (2) 25Cg http://flybase.org/reports/FBgn0005513 - gene - - - "jf21, l(2)jf21, l(2)25Cg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0063298 CR31429 - http://flybase.org/reports/FBgn0063298 non_protein_coding_gene - - - "NEST:bs10g06, BcDNA:AT27571, CR31429" - CR31429 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263648 CR43639 - http://flybase.org/reports/FBgn0263648 non_protein_coding_gene - - - CR43639 - CR43639 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267799 CR46124 - http://flybase.org/reports/FBgn0267799 non_protein_coding_gene - - - CR46124 - CR46124 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266835 CR45297 - http://flybase.org/reports/FBgn0266835 non_protein_coding_gene - - - CR45297 - CR45297 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065829 l(2)SH0354 lethal (2) SH0354 http://flybase.org/reports/FBgn0065829 gene - - - "l(2)SH0354, l(2)SH2 0354" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036729 CG13733 - http://flybase.org/reports/FBgn0036729 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13733 - CG13733 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011878 tRNA:His-GTG-1-4 transfer RNA:Histidine-GTG 1-4 http://flybase.org/reports/FBgn0011878 "FBgn0011876, FBgn0050252, FBgn0060204" tRNA_gene CAC codon-amino acid adaptor activity ; GO:0033426 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033426 cytosol ; GO:0005829 | inferred by curator from GO:0033426 "tRNA[His], His-tRNA, His-tRNA-gtg-gamma, tRNA[His-48], AE002787.trna35-HisGTG, tRNA:H:GTG:AE002787-e, CR30252, tRNA:his:48F, tRNA:His, chr2R.trna17-HisGTG, tRNA-His-GTG-1-4, tRNA:His-GTG-1-4, tRNA:H:48F, CAC" - CR30252 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086600 snoRNA:Psi18S-1347c snoRNA:Psi18S-1347c http://flybase.org/reports/FBgn0086600 snoRNA_gene - - - "snoRNA:203, psi18S-1347c, Dm-203, snoR203, CR33633, Psi18S-1347c, snoRNA:Psi18S-1347c" - CR33633 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019657 sAM16 sAM16 http://flybase.org/reports/FBgn0019657 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available sAM16 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063905 Neurodegeneration-15 Neurodegeneration 15 http://flybase.org/reports/FBgn0063905 gene - - - "Neurodegeneration-15, ND15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,dominant" FBgn0036853 mRpL21 mitochondrial ribosomal protein L21 http://flybase.org/reports/FBgn0036853 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001787 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000003632 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001787 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with SGD:S000003632 "CG9730, MRP-L21, mRpL21" "IPR001787:Ribosomal protein L21, IPR028909:Ribosomal protein L21-like" CG9730 11-Aug-17 DroID_v2017_08 Drer\mrpl21 Scer\MRPL49 Cele\mrpl-21 Xtro\mrpl21 Mmus\Mrpl21 Hsap\MRPL21 "viable,visible" trichogen cell DRSC11100 K -0.528883467 -0.265772714 -0.135289884 0.37723743 1.608117376 0.02218506 FBgn0039817 CG15553 - http://flybase.org/reports/FBgn0039817 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG15553 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG15553 11-Aug-17 DroID_v2017_08 "Drer\slc46a1, Drer\zgc:174356, Drer\hiat1b, Drer\si:ch211-262i1.4, Drer\LOC557306, Drer\hiat1a, Drer\si:dkey-5g14.1, Drer\LOC100002406, Drer\slc46a3" Scer\YJL163C "Cele\Y4C6B.5, Cele\C46C11.2, Cele\F40F9.5, Cele\Y43F8A.5" "Xtro\slc46a2, Xtro\mfsd14b, Xtro\mfsd14a, Xtro\slc46a1" "Mmus\Slc46a2, Mmus\Slc46a1, Mmus\Mfsd14b, Mmus\Mfsd14a, Mmus\Slc46a3" "Hsap\SLC46A1, Hsap\MFSD14A, Hsap\SLC46A3, Hsap\MFSD14B, Hsap\SLC46A2" "partially lethal - majority die,some die during pupal stage" FBgn0011480 l(3)neo47 lethal (3) neo47 http://flybase.org/reports/FBgn0011480 - gene - - - l(3)neo47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0038296 CG6752 - http://flybase.org/reports/FBgn0038296 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6752 "IPR001841:Zinc finger, RING-type, IPR003877:SPRY domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001870:B30.2/SPRY domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6752 11-Aug-17 DroID_v2017_08 "Drer\hnrnpul1l, Drer\rnf123, Drer\hnrnpul1, Drer\si:ch211-107m4.1, Drer\rspry1, Drer\hnrnpua" - Cele\F16A11.1 "Xtro\hnrnpul1, Xtro\rspry1, Xtro\rnf123" "Mmus\Hnrnpu, Mmus\Rspry1, Mmus\Hnrnpul1, Mmus\Rnf123" "Hsap\HNRNPUL1, Hsap\RNF123, Hsap\RSPRY1" "viable,fertile" heart primordium FBgn0000811 fs(1)K79 female sterile (1) K79 http://flybase.org/reports/FBgn0000811 - gene - - - fs(1)K79 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "dorsal appendage,maternal effect" FBgn0060484 l(3)S110709b lethal (3) S110709b http://flybase.org/reports/FBgn0060484 gene - - - "1107/09, l(3)S110709b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0004629 Cys Cystatin-like http://flybase.org/reports/FBgn0004629 "FBgn0004121, FBgn0062905" protein_coding_gene cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from electronic annotation with InterPro:IPR000010 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG8050, clone 2.34, anon-EST:Liang-2.34, BcDNA:RH72992, Cys, cys" "IPR018073:Proteinase inhibitor I25, cystatin, conserved site, IPR000010:Cystatin domain" CG8050 11-Aug-17 DroID_v2017_08 - - - - - - adult stage viable FBgn0051423 Ionotropic receptor 94c http://flybase.org/reports/FBgn0051423 - protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir94c, DmelIR94c, CG31423, IR94c" - CG31423 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259968 Sfp60F Seminal fluid protein 60F http://flybase.org/reports/FBgn0259968 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp60F, CG42478" - CG42478 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015478 l(2)45Bb lethal (2) 45Bb http://flybase.org/reports/FBgn0015478 - gene - - - l(2)45Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0061145 l(3)S000306 lethal (3) S000306 http://flybase.org/reports/FBgn0061145 gene - - - "0003/06, l(3)S000306" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0086029 snoRNA:Me18S-A1597 - http://flybase.org/reports/FBgn0086029 snoRNA_gene - - - "snoRNA:Me18S-A1597, Me18S-Am1597, CR34658" - CR34658 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033887 St4 Sulfotransferase 4 http://flybase.org/reports/FBgn0033887 protein_coding_gene sulfotransferase activity ; GO:0008146 | inferred from direct assay sulfation ; GO:0051923 | inferred from direct assay xenobiotic metabolic process ; GO:0006805 | inferred from direct assay cytosol ; GO:0005829 | non-traceable author statement "CG6704, dmST4, St4, st4" "IPR000863:Sulfotransferase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG6704 11-Aug-17 DroID_v2017_08 "Drer\sult2st1, Drer\sult1st5, Drer\sult1st3, Drer\sult6b1, Drer\sult2st2, Drer\sult5a1, Drer\sult1st6, Drer\sult1st2, Drer\sult3st1, Drer\sult3st4, Drer\sult1st8, Drer\sult1st4, Drer\sult1st1, Drer\sult2st3, Drer\si:dkey-236e20.3, Drer\sult3st3, Drer\sult3st2, Drer\sult1st7, Drer\sult4a1" - Cele\ssu-1 "Xtro\sult6b1, Xtro\sult2b1, Xtro\sult1c2, Xtro\LOC100497264, Xtro\sult4a1, Xtro\sult1a1, Xtro\sult1c4, Xtro\LOC100487424, Xtro\sult1e1, Xtro\LOC496998" "Mmus\Sult2a4, Mmus\Sult3a1, Mmus\Sult1c1, Mmus\Sult2a3, Mmus\Sult2a7, Mmus\Sult1e1, Mmus\Sult2a6, Mmus\Sult6b2, Mmus\Sult2a5, Mmus\Sult2a8, Mmus\Sult5a1, Mmus\Sult3a2, Mmus\Sult2a1, Mmus\Sult1d1, Mmus\Sult6b1, Mmus\Sult1a1, Mmus\Sult2b1, Mmus\Sult1b1, Mmus\Sult4a1, Mmus\Sult1c2, Mmus\Sult2a2" "Hsap\SULT1C2, Hsap\SULT2A1, Hsap\SULT1A2, Hsap\SULT1C4, Hsap\SULT1B1, Hsap\SULT1C3, Hsap\SULT1A4, Hsap\SULT1E1, Hsap\SULT2B1, Hsap\SULT1A3, Hsap\SULT6B1, Hsap\SULT1A1, Hsap\SULT4A1" FBgn0262263 mir-969 mir-969 stem loop http://flybase.org/reports/FBgn0262263 miRNA_gene - germ cell development ; GO:0007281 | inferred from mutant phenotype - "dme-mir-969, mir-969, CR42970, miR-969" - CR42970 11-Aug-17 DroID_v2017_08 - - - - - - lethal "germline cell,maternal effect" FBgn0034505 CG16739 - http://flybase.org/reports/FBgn0034505 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG16739 - CG16739 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015591 AstA Allatostatin A http://flybase.org/reports/FBgn0015591 "FBgn0012040, FBgn0039220, FBgn0047160" protein_coding_gene "neuropeptide hormone activity ; GO:0005184 | inferred from electronic annotation with InterPro:IPR010276 neuropeptide hormone activity ; GO:0005184 | non-traceable author statement neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with AstA-R2, AstA-R1 hormone activity ; GO:0005179 | non-traceable author statement receptor binding ; GO:0005102 | non-traceable author statement" neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay negative regulation of juvenile hormone biosynthetic process ; GO:0045968 | non-traceable author statement extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "AstA-1, CG13633, Drm-AST-4, Drm-AST-3, Drm-AST-2, DST-4A, DST-3A, DST-2A, DST-1A, DAP-A, AST-1, Drm-AST-A, Drm-AST-1, DAP, BcDNA:RE16553, AST, AstA, ast, AST-A, Ast-A, Ast, ASA, AST-3, AST-4, AstA-2, AstA-3, AstA-4, AS, ALLS, Allatostatin A1, Allatostatin A2, Allatostatin A3, Allatostatin A4" IPR010276:Allatostatin CG13633 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0024508 l(3)01010 lethal (3) 01010 http://flybase.org/reports/FBgn0024508 - gene - - - l(3)01010 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020332 anon-67EFa anon-67EFa http://flybase.org/reports/FBgn0020332 - gene - - - "8H7, anon-67EFa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050103 CG30103 - http://flybase.org/reports/FBgn0050103 protein_coding_gene 5'-nucleotidase activity ; GO:0008253 | NOT inferred from direct assay "nucleotide catabolic process ; GO:0009166 | inferred from electronic annotation with InterPro:IPR006179, InterPro:IPR008334" - "CG4837, BcDNA:AT08275, CG30103" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006179:5'-Nucleotidase/apyrase, IPR008334:5'-Nucleotidase, C-terminal, IPR029052:Metallo-dependent phosphatase-like" CG30103 11-Aug-17 DroID_v2017_08 Drer\nt5e Scer\YHR202W - Xtro\nt5e "Mmus\4933425L06Rik, Mmus\Nt5e" Hsap\NT5E viable FBgn0031406 Send1 Spermathecal endopeptidase 1 http://flybase.org/reports/FBgn0031406 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "CG17012, SP163, Send1" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG17012 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.9, Drer\si:ch211-165b19.8, Drer\gzmk" - Cele\try-1 Xtro\gzmak "Mmus\Prss36, Mmus\Cma2, Mmus\Prss53, Mmus\Klk14" "Hsap\PRSS53, Hsap\PRSS36, Hsap\AZU1, Hsap\KLK10, Hsap\GZMK" "viable,visible" trichogen cell FBgn0020328 anon-72BCa anon-72BCa http://flybase.org/reports/FBgn0020328 - gene - - - "557, anon-72BCa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014210 l(2)21Ca lethal (2) 21Ca http://flybase.org/reports/FBgn0014210 - gene - - - l(2)21Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible" FBgn0261838 pre-mod(mdg4)-Z - http://flybase.org/reports/FBgn0261838 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-Z, CG42770" "IPR007588:Zinc finger, FLYWCH-type" CG42770 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065600 l(2)SH0870 lethal (2) SH0870 http://flybase.org/reports/FBgn0065600 gene - - - "l(2)SH0870, l(2)SH2 0870" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051384 CR31384 - http://flybase.org/reports/FBgn0051384 non_protein_coding_gene - - - CR31384 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034860 CG9812 - http://flybase.org/reports/FBgn0034860 protein_coding_gene - - - "BcDNA:RH38235, CG9812" - CG9812 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0264472 CG43880 - http://flybase.org/reports/FBgn0264472 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43880, lincRNA.466" - CG43880 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014882 Ssb-c7a Single stranded-binding protein c7a http://flybase.org/reports/FBgn0014882 - gene - - - "c7a, Ssb-c7a" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000453 Dip-A Dipeptidase A http://flybase.org/reports/FBgn0000453 - gene dipeptidyl-peptidase activity ; GO:0008239 | inferred from direct assay tripeptidyl-peptidase activity ; GO:0008240 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay - "Dip, DipA, Dip-A" - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0085353 CG34324 - http://flybase.org/reports/FBgn0085353 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG34324, CG12726" IPR002557:Chitin binding domain CG34324 11-Aug-17 DroID_v2017_08 - - "Cele\abu-4, Cele\cpg-2, Cele\pqn-78, Cele\abu-5, Cele\pqn-79, Cele\C39D10.7, Cele\R02F2.4, Cele\cpg-1" - Mmus\Gm19668 - FBgn0060465 l(3)S114414b lethal (3) S114414b http://flybase.org/reports/FBgn0060465 gene - - - "1144/14, l(3)S114414b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259448 EP-55 - http://flybase.org/reports/FBgn0259448 gene - - - EP-55 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0062705 EP1065 EP1065 http://flybase.org/reports/FBgn0062705 gene - - - "EP(2)1065, EP1065" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025000 E(vvl)23 E(vvl)23 http://flybase.org/reports/FBgn0025000 - gene - - - "E(dfr)23, E(VVL)23, E(vvl)23" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263257 Cngl Cyclic nucleotide-gated ion channel-like http://flybase.org/reports/FBgn0263257 protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 intracellular cyclic nucleotide activated cation channel activity ; GO:0005221 | inferred from sequence or structural similarity with CngA transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 cation transport ; GO:0006812 | inferred from sequence or structural similarity with CngA cyclic-nucleotide-mediated signaling ; GO:0019935 | inferred from sequence or structural similarity with CngA intracellular cyclic nucleotide activated cation channel complex ; GO:0017071 | inferred from sequence or structural similarity with CngA integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 "cngl, CG43395, CG9176, CG18210, CNGL, dmCNG3, Cngl, mdcds_55060" "IPR005821:Ion transport domain, IPR000595:Cyclic nucleotide-binding domain, IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR014710:RmlC-like jelly roll fold" CG43395 11-Aug-17 DroID_v2017_08 "Drer\LOC100334711, Drer\cnga4, Drer\cnga1, Drer\si:dkey-22i16.2, Drer\cnga3a, Drer\cnga5" - - "Xtro\cnga1, Xtro\cnga3, Xtro\cnga4" "Mmus\Hcn2, Mmus\Cnga3, Mmus\Hcn3, Mmus\Cnga4, Mmus\Hcn1, Mmus\Hcn4, Mmus\Cnga1, Mmus\Cnga2" "Hsap\CNGA3, Hsap\CNGA4, Hsap\CNGA1, Hsap\CNGA2" DRSC20318 IE 0.880695083 -3.482593379 2.007633778 -2.602725767 -0.480708544 0.030587315 FBgn0266564 CR45103 - http://flybase.org/reports/FBgn0266564 non_protein_coding_gene - - - "CR45103, lincRNA.803" - CR45103 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002401 l(3)99Db lethal (3) 99Db http://flybase.org/reports/FBgn0002401 - gene - - - l(3)99Db - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065799 l(2)SH0412 lethal (2) SH0412 http://flybase.org/reports/FBgn0065799 gene - - - "l(2)SH0412, l(2)SH2 0412" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051547 NKCC sodium potassium chloride cotransporter http://flybase.org/reports/FBgn0051547 protein_coding_gene cation:chloride symporter activity ; GO:0015377 | inferred from electronic annotation with InterPro:IPR004842 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR004842, InterPro:IPR018491 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004842 "NKCC, CG31547, CG2509, CG10544" "IPR004841:Amino acid permease/ SLC12A domain, IPR004842:SLC12A transporter family, IPR018491:SLC12A transporter, C-terminal" CG31547 11-Aug-17 DroID_v2017_08 "Drer\slc12a8, Drer\slc12a10.1, Drer\slc12a10.2, Drer\si:ch211-220f12.1, Drer\slc12a2, Drer\slc12a1, Drer\slc12a3, Drer\slc12a10.3" Scer\VHC1 "Cele\B0303.11, Cele\nkcc-1" "Xtro\slc12a1, Xtro\slc12a3" "Mmus\Slc12a3, Mmus\Slc12a5, Mmus\Slc12a2, Mmus\Slc12a8, Mmus\Slc12a1" "Hsap\SLC12A8, Hsap\SLC12A2, Hsap\SLC12A5, Hsap\SLC12A1, Hsap\SLC12A3" viable FBgn0005173 l(2)M lethal of Mohr http://flybase.org/reports/FBgn0005173 - gene - - - l(2)M - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015694 E(Sxl) Enhancer of Sex-lethal http://flybase.org/reports/FBgn0015694 - gene - - - E(Sxl) - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037396 CG11459 - http://flybase.org/reports/FBgn0037396 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 aminopeptidase activity ; GO:0004177 | inferred from biological aspect of ancestor with PANTHER:PTN001391531 cysteine-type endopeptidase activator activity involved in apoptotic process ; GO:0008656 | inferred from biological aspect of ancestor with PANTHER:PTN001391516 positive regulation of apoptotic signaling pathway ; GO:2001235 | inferred from biological aspect of ancestor with PANTHER:PTN001391516 immune response ; GO:0006955 | inferred from biological aspect of ancestor with PANTHER:PTN000749203 positive regulation of peptidase activity ; GO:0010952 | inferred from biological aspect of ancestor with PANTHER:PTN001391516 proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 CG11459 "IPR025660:Cysteine peptidase, histidine active site, IPR000668:Peptidase C1A, papain C-terminal, IPR013128:Peptidase C1A, IPR013201:Cathepsin propeptide inhibitor domain (I29), IPR015644:Peptidase C1A, cathepsin K" CG11459 11-Aug-17 DroID_v2017_08 "Drer\ctsll, Drer\ctslb, Drer\MGC174155, Drer\si:dkey-267n13.1, Drer\ctsz, Drer\si:dkey-269i1.4, Drer\zgc:174153, Drer\LOC100536033, Drer\si:dkey-239j18.3, Drer\cts12, Drer\si:dkey-228a15.1, Drer\ctsc, Drer\ctss2.2, Drer\ctsba, Drer\si:dkey-239j18.2, Drer\ctsh, Drer\si:dkey-183k8.2, Drer\LOC100333521, Drer\ctsla, Drer\ctsl.1, Drer\zgc:110239, Drer\wu:fa26c03, Drer\zgc:103438, Drer\ctsk, Drer\ctss2.1, Drer\zgc:174855, Drer\ctss1, Drer\ctsbb" - "Cele\Y71H2AR.2, Cele\K02E7.10" "Xtro\ctsb, Xtro\ctsl, Xtro\ctsz, Xtro\ctsc, Xtro\ctss, Xtro\ctsv, Xtro\LOC100498238, Xtro\LOC100490139, Xtro\ctsh" "Mmus\Ctsk, Mmus\Ctsll3, Mmus\Ctsb, Mmus\BC051665, Mmus\Cts7, Mmus\Ctsq, Mmus\Ctss, Mmus\Ctsz, Mmus\Ctsc, Mmus\Ctsh, Mmus\Ctsr, Mmus\Ctla2a, Mmus\Ctsj, Mmus\Cts3, Mmus\Cts8, Mmus\Ctsm, Mmus\Ctla2b, Mmus\Cts6, Mmus\Ctsl, Mmus\4930486L24Rik" "Hsap\CTSB, Hsap\CTSV, Hsap\CTSC, Hsap\CTSH, Hsap\CTSZ, Hsap\CTSK, Hsap\CTSS, Hsap\CTSL" viable FBgn0053325 CG33325 - http://flybase.org/reports/FBgn0053325 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33325 - CG33325 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035455 CG10862 - http://flybase.org/reports/FBgn0035455 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12474 extracellular space ; GO:0005615 | inferred from direct assay CG10862 "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG10862 11-Aug-17 DroID_v2017_08 "Drer\ube2d2, Drer\ube2d1a, Drer\ube2e3, Drer\ube2d3, Drer\ube2e2, Drer\ube2t, Drer\ube2d1b, Drer\ube2e1, Drer\ube2na, Drer\ube2nb, Drer\ube2d4" "Scer\UBC4, Scer\PEX4, Scer\UBC13, Scer\UBC5" "Cele\ubc-24, Cele\ubc-22, Cele\let-70" "Xtro\ube2e3, Xtro\ube2e2, Xtro\ube2e1, Xtro\ube2d1, Xtro\ube2d4, Xtro\ube2n, Xtro\ube2d3" "Mmus\Ube2d2a, Mmus\Ube2e3, Mmus\Ube2e1, Mmus\Ube2d3, Mmus\Ube2d2b, Mmus\Ube2dnl1, Mmus\Ube2e2, Mmus\Ube2t, Mmus\Ube2dnl2, Mmus\Ube2d1, Mmus\Ube2n" "Hsap\UBE2E1, Hsap\UBE2N, Hsap\UBE2D2, Hsap\UBE2D4, Hsap\UBE2NL, Hsap\UBE2D1, Hsap\UBE2D3, Hsap\UBE2T, Hsap\UBE2E2, Hsap\UBE2E3" viable FBgn0265400 EP2161 - http://flybase.org/reports/FBgn0265400 gene - - - EP2161 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260572 MENE-W12 - http://flybase.org/reports/FBgn0260572 gene - - - MENE-W12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye disc,somatic clone" FBgn0042130 CG18807 - http://flybase.org/reports/FBgn0042130 protein_coding_gene - - - CG18807 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020624 PZ22 PZ22 http://flybase.org/reports/FBgn0020624 - gene - - - PZ22 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069952 CG41071 - http://flybase.org/reports/FBgn0069952 protein_coding_gene - - - "CG40168, CG41071" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052633 CG32633 - http://flybase.org/reports/FBgn0052633 protein_coding_gene - - - "CG1733, anon-WO0140519.164, CG32633" "IPR006616:DM9 repeat, IPR024518:Domain of unknown function DUF3421" CG32633 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065765 l(2)SH0474 lethal (2) SH0474 http://flybase.org/reports/FBgn0065765 gene - - - "l(2)SH0474, l(2)SH2 0474" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036491 Best4 Bestrophin 4 http://flybase.org/reports/FBgn0036491 protein_coding_gene chloride channel activity ; GO:0005254 | inferred from sequence or structural similarity with Best1 chloride transport ; GO:0006821 | inferred from sequence or structural similarity with Best1 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Best1 "CT22395, dbest4, CG7259, Best4, dBest4" "IPR000615:Bestrophin, IPR021134:Bestrophin/UPF0187" CG7259 11-Aug-17 DroID_v2017_08 "Drer\best4, Drer\best1, Drer\best2" - "Cele\best-25, Cele\best-20, Cele\best-23, Cele\best-10, Cele\best-1, Cele\best-4, Cele\best-3, Cele\best-2, Cele\best-18, Cele\best-17, Cele\best-16, Cele\best-6, Cele\best-5, Cele\best-21, Cele\best-13, Cele\best-8, Cele\best-22, Cele\best-9, Cele\best-14, Cele\best-19, Cele\sma-10, Cele\best-26, Cele\best-12, Cele\C09B9.85, Cele\best-11, Cele\best-15, Cele\best-24, Cele\best-7" "Xtro\best3, Xtro\best2, Xtro\best4, Xtro\best1" "Mmus\Best2, Mmus\Best3, Mmus\Best1" "Hsap\BEST1, Hsap\BEST4, Hsap\BEST2, Hsap\BEST3" viable FBgn0264836 CG44044 - http://flybase.org/reports/FBgn0264836 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44044 - CG44044 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042145 CG18822 - http://flybase.org/reports/FBgn0042145 protein_coding_gene - - - CG18822 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023408 Ars-region52 Autonomous replicating sequence region 52 http://flybase.org/reports/FBgn0023408 - region - - - "dARS52, Ars-region52, Ars52" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069122 ms(2)Z2181 ms(2)Z2181 http://flybase.org/reports/FBgn0069122 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(2)Z2181 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile spermatozoon FBgn0283652 Rpp30 RNaseP protein p30 http://flybase.org/reports/FBgn0283652 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000315300 ribonuclease P activity ; GO:0004526 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000315300 "tRNA processing ; GO:0008033 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype RNA phosphodiester bond hydrolysis, endonucleolytic ; GO:0090502 | inferred from biological aspect of ancestor with PANTHER:PTN000315301 tRNA processing ; GO:0008033 | inferred from biological aspect of ancestor with PANTHER:PTN000315301 tRNA processing ; GO:0008033 | inferred from mutant phenotype" ribonuclease P complex ; GO:0030677 | inferred from sequence or structural similarity nucleolar ribonuclease P complex ; GO:0005655 | inferred from biological aspect of ancestor with PANTHER:PTN000315300 "RNase P, l(2)k01901, #19/1, CG11606, Rpp30, coconut" "IPR002738:RNase P subunit p30, IPR016195:Polymerase/histidinol phosphatase-like" CG11606 11-Aug-17 DroID_v2017_08 Drer\rpp30 Scer\RPP1 Cele\H35B03.2 Xtro\rpp30 Mmus\Rpp30 Hsap\RPP30 "lethal,recessive,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0020612 Ufo Ultra female overexpression http://flybase.org/reports/FBgn0020612 - gene - - - Ufo - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,non-suppressor of variegation" pigment cell FBgn0035603 Pfdn4 Prefoldin 4 http://flybase.org/reports/FBgn0035603 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR002777 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000473575 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000473575 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000473575 prefoldin complex ; GO:0016272 | colocalizes_with inferred from direct assay "BcDNA:SD11994, CG10635, Pfdn4, pfdn4" "IPR002777:Prefoldin beta-like, IPR016661:Prefoldin, subunit 4" CG10635 11-Aug-17 DroID_v2017_08 Drer\pfdn4 Scer\GIM3 Cele\pfd-4 Xtro\pfdn4 Mmus\Pfdn4 Hsap\PFDN4 "viable,body color defective" mesothoracic tergum FBgn0262194 mir-2489 mir-2489 stem loop http://flybase.org/reports/FBgn0262194 miRNA_gene - - - "dme-mir-2489, mir-2489, CR42901, miR-2489" - CR42901 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263200 Galt Galactose-1-phosphate uridylyltransferase http://flybase.org/reports/FBgn0263200 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001937, InterPro:IPR019779 UDP-glucose:hexose-1-phosphate uridylyltransferase activity ; GO:0008108 | inferred from mutant phenotype" "galactose metabolic process ; GO:0006012 | inferred from electronic annotation with InterPro:IPR001937, InterPro:IPR005849, InterPro:IPR005850, InterPro:IPR019779 adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype galactose homeostasis ; GO:0033501 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available "CG9232, Galt, GALT, dGALT" "IPR001937:Galactose-1-phosphate uridyl transferase, class I, IPR005849:Galactose-1-phosphate uridyl transferase, N-terminal, IPR005850:Galactose-1-phosphate uridyl transferase, C-terminal, IPR011146:HIT-like domain, IPR019779:Galactose-1-phosphate uridyl transferase, class I His-active site" CG9232 11-Aug-17 DroID_v2017_08 Drer\galt Scer\GAL7 Cele\ZK1058.3 Xtro\galt "Mmus\Galt, Mmus\Il11ra1, Mmus\Gm2002, Mmus\LOC100861969, Mmus\Gm13305" "Hsap\GALT, Hsap\IL11RA" FBgn0039654 Brd8 Bromodomain containing 8 http://flybase.org/reports/FBgn0039654 protein_coding_gene - histone acetylation ; GO:0016573 | inferred from direct assay histone exchange ; GO:0043486 | inferred from direct assay negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay "dBrd8, CG14514, Brd8" IPR001487:Bromodomain CG14514 11-Aug-17 DroID_v2017_08 "Drer\brd8, Drer\si:ch211-59d17.3" - "Cele\F59E12.1, Cele\droe-8" Xtro\brd8 "Mmus\Brd8, Mmus\4933408B17Rik" Hsap\BRD8 viable DRSC28811 K -1.414981366 -1.538080134 FBgn0032170 CG4658 - http://flybase.org/reports/FBgn0032170 protein_coding_gene - - - CG4658 IPR006571:TLDc domain CG4658 11-Aug-17 DroID_v2017_08 - Scer\RTC5 "Cele\Y39A3CL.4, Cele\eak-7" - - - "viable,fertile" FBgn0011130 l(1)Q204 lethal (1) Q204 http://flybase.org/reports/FBgn0011130 FBgn0010210 gene - - - l(1)Q204 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0062655 EP344 EP344 http://flybase.org/reports/FBgn0062655 gene - - - "EP(3)0344, EP344" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035076 Ance-5 Ance-5 http://flybase.org/reports/FBgn0035076 protein_coding_gene peptidyl-dipeptidase activity ; GO:0008241 | inferred from electronic annotation with InterPro:IPR001548 metallopeptidase activity ; GO:0008237 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001548 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001548 "CG10142, Ance-5, ance-5" "IPR001548:Peptidase M2, peptidyl-dipeptidase A" CG10142 11-Aug-17 DroID_v2017_08 "Drer\ace, Drer\ace2, Drer\si:dkey-194e6.1" - Cele\acn-1 "Xtro\tmem27, Xtro\ace2, Xtro\ace" "Mmus\Ace2, Mmus\Tmem27, Mmus\Ace, Mmus\Ace3" "Hsap\TMEM27, Hsap\ACE2, Hsap\ACE" viable FBgn0015916 bk87 bk87 http://flybase.org/reports/FBgn0015916 - gene - - - bk87 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016641 PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 http://flybase.org/reports/FBgn0016641 - protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from direct assay R7 cell fate commitment ; GO:0007465 | inferred from genetic interaction with Raf inferred from genetic interaction with Ras85D inferred from genetic interaction with Dsor1 protein dephosphorylation ; GO:0006470 | non-traceable author statement negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D negative regulation of ERK1 and ERK2 cascade ; GO:0070373 | inferred from genetic interaction with Ras85D mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype Ras protein signal transduction ; GO:0007265 | inferred from genetic interaction with Raf inferred from genetic interaction with Ras85D inferred from genetic interaction with Dsor1 cytoplasm ; GO:0005737 | inferred from direct assay "ptp-er, CG9856, ER2-5, PTP-ER" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR003595:Protein-tyrosine phosphatase, catalytic" CG9856 11-Aug-17 DroID_v2017_08 "Drer\ptprr, Drer\ptpn22, Drer\ptpn5, Drer\ca16b, Drer\ptprz1b, Drer\ptpn2b, Drer\ptprga, Drer\ptpn2a, Drer\ca16c, Drer\ptpn18, Drer\ptpn1" "Scer\PTP1, Scer\PTP2, Scer\PTP3" "Cele\C50F2.5, Cele\C43E11.5, Cele\egg-4, Cele\egg-5" "Xtro\ptprr, Xtro\ptpn2, Xtro\ptprz1, Xtro\ptpn23, Xtro\ptpn12, Xtro\ptpn22, Xtro\ptpn1" "Mmus\Ptpn2, Mmus\Ptpn7, Mmus\Ptpn23, Mmus\Ptpn22, Mmus\Ptpn20, Mmus\Ptprg, Mmus\Ptpn18, Mmus\Ptpn12, Mmus\Ptprr, Mmus\Ptpn5, Mmus\Ptpn1" "Hsap\PTPN22, Hsap\PTPN7, Hsap\PTPN1, Hsap\PTPN2, Hsap\PTPRR, Hsap\PTPN5, Hsap\PTPN23, Hsap\PTPN18, Hsap\PTPRG, Hsap\PTPN12, Hsap\PTPN20" "viable,fertile,visible,recessive,lethal" "photoreceptor cell R7,ectopic,eye,eye photoreceptor cell,ommatidium,supernumerary" DRSC04636 IEK 2.41765926 0.824558718 2.32666375 -0.443680677 2.721199158 1.701721534 FBgn0000726 Frd Freckled http://flybase.org/reports/FBgn0000726 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available Frd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,body color defective,dominant" "fat body,pericardial cell" FBgn0000074 amb amber http://flybase.org/reports/FBgn0000074 - gene - - - amb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,male fertile,female sterile,body color defective,male sterile,eye color defective,poor" "macrochaeta,pigment cell" FBgn0004996 Cr-2 Cream 2 http://flybase.org/reports/FBgn0004996 - gene - - - Cr-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0024265 acd(2)5G23 auditory courtship defective 5G23 http://flybase.org/reports/FBgn0024265 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "acd(2)5G23, 5G23" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective,courtship behavior defective,male fertile" FBgn0259359 C518 - http://flybase.org/reports/FBgn0259359 gene - - - C518 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing hair,chaeta" FBgn0011234 tmx trail mix http://flybase.org/reports/FBgn0011234 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(2)05235, tmx" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0060924 l(3)S042207 lethal (3) S042207 http://flybase.org/reports/FBgn0060924 gene - - - "0422/07, l(3)S042207" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0061065 l(3)S020802b lethal (3) S020802b http://flybase.org/reports/FBgn0061065 gene - - - "0208/02, l(3)S020802b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0263038 CG43333 - http://flybase.org/reports/FBgn0263038 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43333, CG32972, BG:DS01523.2, CG15291" IPR000782:FAS1 domain CG43333 11-Aug-17 DroID_v2017_08 "Drer\postnb, Drer\tgfbi, Drer\postna" Scer\YLR001C Cele\F26E4.7 "Xtro\tgfbi, Xtro\postn" "Mmus\Postn, Mmus\Tgfbi" "Hsap\POSTN, Hsap\TGFBI" "viable,fertile,lethal" FBgn0016811 l(1)L12 lethal (1) L12 http://flybase.org/reports/FBgn0016811 - gene - - - "l(1)L12, L12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005329 P43 P43 http://flybase.org/reports/FBgn0005329 - gene - - - P43 - - 11-Aug-17 DroID_v2017_08 - - - - - - "optomotor response defective,neurophysiology defective,neuroanatomy defective,phototaxis defective,behavior defective" "optic lobe,brain,lamina" FBgn0260493 l(3)2332 - http://flybase.org/reports/FBgn0260493 gene - axonogenesis ; GO:0007409 | inferred from mutant phenotype - l(3)2332 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective dendritic arborizing neuron FBgn0004519 l(4)102CDc lethal (4) 102CDc http://flybase.org/reports/FBgn0004519 - gene - - - "l(4)PT-3, l(4)4, l(4)AM-2, l(4)18, l(4)102CDc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" FBgn0065698 l(2)SH0627 lethal (2) SH0627 http://flybase.org/reports/FBgn0065698 gene - - - "l(2)SH0627, l(2)SH2 0627" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020891 Su(osk)M26 Suppressor of oskar M26 http://flybase.org/reports/FBgn0020891 - gene - - - "M26, Su(osk)M26" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028499 CG7985 - http://flybase.org/reports/FBgn0028499 protein_coding_gene - - mitochondrion ; GO:0005739 | inferred from direct assay "BcDNA:GH04120, CG7985" IPR017853:Glycoside hydrolase superfamily CG7985 11-Aug-17 DroID_v2017_08 "Drer\zgc:113333, Drer\hexdc" - "Cele\hex-2, Cele\hex-3, Cele\hex-4, Cele\hex-5" Xtro\hexdc Mmus\Hexdc Hsap\HEXDC "viable,fertile" FBgn0031089 CG9572 - http://flybase.org/reports/FBgn0031089 protein_coding_gene - - - "CT17356, CG9572" "IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site" CG9572 11-Aug-17 DroID_v2017_08 "Drer\col28a1a, Drer\jag1b, Drer\jag1a, Drer\crb2a, Drer\LOC562634, Drer\LOC100332841, Drer\adgrf6, Drer\si:ch73-173h19.3, Drer\jag2a, Drer\sned1, Drer\crb2b, Drer\chn1, Drer\zgc:158328, Drer\chn2, Drer\adgrl4, Drer\svep1, Drer\scube3, Drer\megf6b, Drer\LOC100535882, Drer\fbln1, Drer\efemp1, Drer\matn3a, Drer\dpy19l1l, Drer\scube1, Drer\dlb, Drer\col28a1a, Drer\fbln7, Drer\ltbp3, Drer\dlk2, Drer\jag2b" - "Cele\cutl-18, Cele\noah-2, Cele\H03E18.1, Cele\chin-1, Cele\F52C9.5, Cele\F32B4.8, Cele\C16D9.1, Cele\noah-1, Cele\cutl-27, Cele\C34C12.7, Cele\T23F1.5, Cele\ZC449.1, Cele\H42K12.3, Cele\cutl-17, Cele\T26C5.2, Cele\R07A4.4, Cele\ZC449.2, Cele\let-653" "Xtro\f12, Xtro\hgfac, Xtro\matn4, Xtro\nell1, Xtro\crb2, Xtro\svep1, Xtro\fbn1, Xtro\col14a1, Xtro\jag1, Xtro\chn2, Xtro\notch1, Xtro\ltbp4, Xtro\chn1" "Mmus\Crb2, Mmus\Dll4, Mmus\Sned1, Mmus\Hgfac, Mmus\Egfl7, Mmus\Vwa1, Mmus\Hmcn2, Mmus\Jag1, Mmus\Jag2, Mmus\Chn1, Mmus\Fbn1, Mmus\Cfc1, Mmus\Col22a1, Mmus\Dlk1, Mmus\Scube3, Mmus\F12, Mmus\Col28a1, Mmus\Habp2, Mmus\Svep1, Mmus\Chn2, Mmus\Vwde, Mmus\Tdgf1, Mmus\Fbln7, Mmus\Matn3, Mmus\Scube2, Mmus\Ltbp4, Mmus\Vwce, Mmus\Dll3, Mmus\Ltbp1, Mmus\Dlk2" "Hsap\DLK2, Hsap\LTBP1, Hsap\CHN1, Hsap\CFC1, Hsap\SCUBE2, Hsap\F12, Hsap\VWCE, Hsap\SNED1, Hsap\JAG2, Hsap\CHN2, Hsap\DLK1, Hsap\DLL3, Hsap\EGFL7, Hsap\COL14A1, Hsap\FBLN7, Hsap\COL22A1, Hsap\DLL4, Hsap\CFC1B, Hsap\LOC100996717, Hsap\HABP2, Hsap\NOTCH2NL, Hsap\SCUBE3, Hsap\MATN3, Hsap\HGFAC, Hsap\VWA1, Hsap\TDGF1, Hsap\JAG1, Hsap\SVEP1, Hsap\CRB2, Hsap\EYS" FBgn0036799 CG13380 - http://flybase.org/reports/FBgn0036799 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13380 - CG13380 11-Aug-17 DroID_v2017_08 - - Cele\W09D6.5 - - - FBgn0013683 mt:ND4L mitochondrial NADH-ubiquinone oxidoreductase chain 4L http://flybase.org/reports/FBgn0013683 FBgn0002867 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from biological aspect of ancestor with PANTHER:PTN000153441 ATP synthesis coupled electron transport ; GO:0042773 | inferred from electronic annotation with InterPro:IPR001133 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000153444 "CG34086, URF4L, ND4L, mt:ND4L, nd4L, nad4L" IPR001133:NADH-ubiquinone oxidoreductase chain 4L/K CG34086 11-Aug-17 DroID_v2017_08 Drer\ND4L - Cele\srz-72 Xtro\ND4L Mmus\ND4L Hsap\ND4L FBgn0053797 CR33797 - http://flybase.org/reports/FBgn0053797 pseudogene_attribute - - - "CG33797, CR33797" - CR33797 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005008 dil-3 dilute 3 http://flybase.org/reports/FBgn0005008 - gene - - - dil-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0060624 l(3)S087607b lethal (3) S087607b http://flybase.org/reports/FBgn0060624 gene - - - "0876/07, l(3)S087607b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0058262 CG40262 - http://flybase.org/reports/FBgn0058262 protein_coding_gene - - - CG40262 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040886 CG12528 - http://flybase.org/reports/FBgn0040886 protein_coding_gene - - - CG12528 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052816 CG32816 - http://flybase.org/reports/FBgn0052816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32816 - CG32816 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260594 2L1683 - http://flybase.org/reports/FBgn0260594 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1683 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0028741 fab1 fab1 kinase http://flybase.org/reports/FBgn0028741 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002423 1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308 | inferred from sequence or structural similarity with UniProtKB:Q9Z1T6 zinc ion binding ; GO:0008270 | inferred from sequence or structural similarity with UniProtKB:Q9Z1T6 1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308 | non-traceable author statement 1-phosphatidylinositol-3-phosphate 5-kinase activity ; GO:0000285 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from sequence or structural similarity with UniProtKB:Q9Z1T6 endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype phosphorylation ; GO:0016310 | non-traceable author statement phosphatidylinositol phosphorylation ; GO:0046854 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from direct assay vesicle membrane ; GO:0012506 | inferred from sequence or structural similarity with UniProtKB:Q9Z1T6 "EG:52C10.5, fab1, CG6355, Fab1, fab-1, PIKfyve, l(2)SJB, PtdIns3P" "IPR000306:FYVE zinc finger, IPR000591:DEP domain, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR002498:Phosphatidylinositol-4-phosphate 5-kinase, core, IPR011011:Zinc finger, FYVE/PHD-type, IPR017455:Zinc finger, FYVE-related, IPR027484:Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain, IPR027483:Phosphatidylinositol-4-phosphate 5-kinase, C-terminal, IPR027409:GroEL-like apical domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6355 11-Aug-17 DroID_v2017_08 "Drer\pikfyve, Drer\zfyve28, Drer\cct5" "Scer\CCT5, Scer\PIB2, Scer\FAB1" "Cele\cct-5, Cele\lst-2, Cele\ppk-3" "Xtro\zfyve28, Xtro\pikfyve" "Mmus\Pikfyve, Mmus\Zfyve28, Mmus\Rufy2, Mmus\Cct5" "Hsap\RUFY2, Hsap\CCT5, Hsap\PIKFYVE, Hsap\ZFYVE28" "lethal - all die before end of P-stage,some die during pharate adult stage,size defective,somatic clone,large body" "eye disc,eye,somatic clone,ommatidium,adult head,imaginal disc,embryonic/larval garland cell,endosome14H10W-30)" FBgn0065565 l(2)SH0980 lethal (2) SH0980 http://flybase.org/reports/FBgn0065565 gene - - - "l(2)SH0980, l(2)SH2 0980" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264746 CG44004 - http://flybase.org/reports/FBgn0264746 protein_coding_gene - - - "CG44004, CG34252" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001810:F-box domain" CG44004 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013265 E(var)71 E(var)71 http://flybase.org/reports/FBgn0013265 - gene - - - E(var)71 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0040040 CG17613 - http://flybase.org/reports/FBgn0040040 protein_coding_gene - - - CG17613 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084640 Su(dpp)YE2 Su(dpp)YE2 http://flybase.org/reports/FBgn0084640 gene - - - Su(dpp)YE2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "denticle belt,amnioserosa" FBgn0038316 CG6276 - http://flybase.org/reports/FBgn0038316 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - - CG6276 "IPR004210:BESS motif, IPR006578:MADF domain" CG6276 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-207i20.3, Drer\zgc:152938, Drer\LOC100330838" - "Cele\madf-5, Cele\madf-2, Cele\madf-4, Cele\madf-9, Cele\madf-10, Cele\madf-8, Cele\madf-3" - - - "viable,fertile" FBgn0265922 CR44711 - http://flybase.org/reports/FBgn0265922 non_protein_coding_gene - - - "CR44711, lincRNA.1038" - CR44711 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060423 l(3)S127704a lethal (3) S127704a http://flybase.org/reports/FBgn0060423 gene - - - "1277/04, l(3)S127704a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014286 l(3)64Ae lethal (3) 64Ae http://flybase.org/reports/FBgn0014286 - gene - - - "l(3)SH20, l(3)64Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024272 ZAM\env ZAM element env http://flybase.org/reports/FBgn0024272 - transposable_element_gene - - - "ORF3, ZAM\env, env, ZAM env" "IPR009882:Gypsy, IPR022048:Envelope fusion protein-like" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026427 Su(var)2-HP2 Su(var)2-HP2 http://flybase.org/reports/FBgn0026427 FBgn0033946 protein_coding_gene DNA binding ; GO:0003677 | traceable author statement heterochromatin assembly ; GO:0031507 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype "heterochromatin ; GO:0000792 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | traceable author statement polytene chromosome ; GO:0005700 | traceable author statement heterochromatin ; GO:0000792 | traceable author statement condensed chromosome ; GO:0000793 | inferred from direct assay nuclear heterochromatin ; GO:0005720 | inferred from direct assay" "HP2, CG12864, Su(var)2-HP2, SU(VAR)2-HP2, Hp2" - CG12864 11-Aug-17 DroID_v2017_08 "Drer\leo1, Drer\rp1, Drer\rif1" Scer\YFR016C - "Xtro\rif1, Xtro\leo1" "Mmus\Leo1, Mmus\Dmp1, Mmus\Ibsp, Mmus\Rp1, Mmus\Rif1" "Hsap\RP1, Hsap\MUC12, Hsap\DMP1, Hsap\LEO1, Hsap\IBSP, Hsap\RIF1" "lethal,non-suppressor of variegation,suppressor of variegation,dominant,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "condensed chromosomeB11),polytene chromosomeB11),ganglion mother cell,mesothoracic tergum" FBgn0004207 l(3)84Ee lethal (3) 84Ee http://flybase.org/reports/FBgn0004207 - gene - - - l(3)84Ee - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263939 BG00028 - http://flybase.org/reports/FBgn0263939 gene - - - BG00028 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0030691 Efhc1.1 EF-hand domain containing 1.1 http://flybase.org/reports/FBgn0030691 protein_coding_gene - regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype terminal bouton ; GO:0043195 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay microtubule ; GO:0005874 | colocalizes_with inferred from direct assay "CG8959, Efhc1.1" "IPR006602:Uncharacterised domain DM10, IPR010554:Domain of unknown function DUF1126" CG8959 11-Aug-17 DroID_v2017_08 "Drer\efhc2, Drer\efhc1" - Cele\Y49A10A.1 "Xtro\efhc2, Xtro\efhc1" "Mmus\Efhc1, Mmus\Efhc2" "Hsap\EFHC1, Hsap\EFHC2" "neuroanatomy defective,viable,recessive,neurophysiology defective" "dendritic arborizing neuron | third instar larval stage,NMJ bouton,embryonic/larval neuromuscular junction,synapse | third instar larval stage,dendritic arborizing neuron" FBgn0028576 pp10 pp10 http://flybase.org/reports/FBgn0028576 gene - - - pp10 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044336 5-68 5-68 http://flybase.org/reports/FBgn0044336 gene - - - 5-68 - - 11-Aug-17 DroID_v2017_08 - - - - - - "uncoordinated,recessive,locomotor behavior defective,behavior defective" FBgn0260498 l(3)11534 - http://flybase.org/reports/FBgn0260498 gene - - - l(3)11534 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective dendritic arborizing neuron FBgn0002845 M(SD) Modifier of Segregation Distorter http://flybase.org/reports/FBgn0002845 - gene - - - "M(SD), M(Sd)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053509 CG33509 - http://flybase.org/reports/FBgn0053509 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14398, CG33509" "IPR011009:Protein kinase-like domain, IPR004119:Protein of unknown function DUF227, IPR015897:CHK kinase-like" CG33509 11-Aug-17 DroID_v2017_08 - - "Cele\T16G1.6, Cele\F20D6.5, Cele\Y45G12C.4, Cele\T16G1.3, Cele\E02C12.6, Cele\F49C12.7, Cele\dhs-27, Cele\H37A05.2, Cele\T16G1.4, Cele\F56A4.5, Cele\H06H21.8, Cele\E02C12.10, Cele\C29F7.1, Cele\T16G1.5, Cele\F48G7.12, Cele\E02C12.8, Cele\E02C12.9, Cele\T16G1.7, Cele\F59B1.10, Cele\nhr-246, Cele\C29F7.2, Cele\Y11D7A.8" - - - viable FBgn0020234 Ace::Nrt Ace::Nrt http://flybase.org/reports/FBgn0020234 - engineered_fusion_gene - - - Ace::Nrt - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020793 otri oculi triangulares http://flybase.org/reports/FBgn0020793 - gene - - - otri - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable" ommatidium FBgn0026736 anon-C2 anon-C2 http://flybase.org/reports/FBgn0026736 - gene - - - "C2, anon-C2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029014 l(3)77CDk lethal (3) 77CDk http://flybase.org/reports/FBgn0029014 gene - - - l(3)77CDk - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,visible" macrochaeta FBgn0259926 CG42449 - http://flybase.org/reports/FBgn0259926 protein_coding_gene - - - "CG42449, CG15778" - CG42449 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025785 anon-MMS128 anon-MMS128 http://flybase.org/reports/FBgn0025785 - gene - - - anon-MMS128 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025555 anon-88Bc anon-88Bc http://flybase.org/reports/FBgn0025555 - gene - - - "c1.0/c1.2, anon-88Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0087007 bbg big bang http://flybase.org/reports/FBgn0087007 protein_coding_gene - innate immune response in mucosa ; GO:0002227 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay septate junction ; GO:0005918 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "bbg, CG9587, CG9598, BBG, C96, CG42230" IPR001478:PDZ domain CG42230 11-Aug-17 DroID_v2017_08 "Drer\pdzd2, Drer\si:dkey-92i15.4, Drer\dlg5a, Drer\inadl, Drer\pard3bb, Drer\aim1a, Drer\grip1, Drer\lnx1, Drer\il16, Drer\grid2ipa, Drer\slc9a3r1, Drer\grip2b, Drer\pdzd7b" - Cele\par-3 "Xtro\grid2ip, Xtro\grip1, Xtro\grip2, Xtro\dlg5, Xtro\lnx1" "Mmus\Grasp, Mmus\Lnx1, Mmus\Pdzd2, Mmus\Grip1, Mmus\Pdzd11, Mmus\Grid2ip, Mmus\Pdzph1, Mmus\Il16, Mmus\Ush1c, Mmus\Mpdz, Mmus\Patj, Mmus\Mki67, Mmus\Dlg5, Mmus\Grip2" "Hsap\PATJ, Hsap\PDZD2, Hsap\GRID2IP, Hsap\MPDZ, Hsap\GRASP, Hsap\GRIP1, Hsap\USH1C, Hsap\LNX1, Hsap\DLG5, Hsap\FRMPD2, Hsap\IL16, Hsap\PARD3B" FBgn0259523 B2003 - http://flybase.org/reports/FBgn0259523 gene - - - B2003 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "tarsal segment,arista" FBgn0044031 Mod(rst)K58 Mod(rst)K58 http://flybase.org/reports/FBgn0044031 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "K58, Mod(rst)K58" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263571 mir-4959 mir-4959 stem loop http://flybase.org/reports/FBgn0263571 miRNA_gene - - - "mir-4959, dme-mir-4959, CR43556" - CR43556 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033876 Syngr Synaptogyrin http://flybase.org/reports/FBgn0033876 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype inferred from genetic interaction with shi synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity synaptic vesicle membrane ; GO:0030672 | inferred from biological aspect of ancestor with PANTHER:PTN000851414 neuromuscular junction ; GO:0031594 | inferred from biological aspect of ancestor with PANTHER:PTN000851414 "sng-1, CG10808, Synaptogyrin, gyr, Syngr, synaptogyrin, Gyr" "IPR008253:Marvel domain, IPR016579:Synaptogyrin" CG10808 11-Aug-17 DroID_v2017_08 "Drer\syngr3a, Drer\syngr1b, Drer\syngr2b, Drer\syngr1a, Drer\syngr3b, Drer\syngr2a" - Cele\sng-1 "Xtro\syngr1, Xtro\syngr3, Xtro\syngr2" "Mmus\Syngr1, Mmus\Syngr2, Mmus\Syngr4, Mmus\Syngr3" "Hsap\SYNGR3, Hsap\SYNGR4, Hsap\SYNGR1, Hsap\SYNGR2" "viable,fertile,neuroanatomy defective,lethal,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuromuscular junction,NMJ bouton,endocytic vesicle,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0260075 2L1360 - http://flybase.org/reports/FBgn0260075 gene - - - 2L1360 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0260022 corona-2 corona on 2 http://flybase.org/reports/FBgn0260022 gene - - - corona-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - chorion | germline clone FBgn0264945 CR44114 - http://flybase.org/reports/FBgn0264945 non_protein_coding_gene - - - CR44114 - CR44114 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031476 CG8813 - http://flybase.org/reports/FBgn0031476 protein_coding_gene - - - "anon-WO0140519.96, CG8813" - CG8813 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065926 l(2)SH0145 lethal (2) SH0145 http://flybase.org/reports/FBgn0065926 gene - - - "l(2)SH0145, l(2)SH2 0145" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035131 mthl9 methuselah-like 9 http://flybase.org/reports/FBgn0035131 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "Mth-9, CG17084, anon-WO0170980.164, anon-WO0170980.163, mthl9" "IPR010596:Methuselah, N-terminal domain, IPR023311:Methuselah ectodomain, domain 2" CG17084 11-Aug-17 DroID_v2017_08 "Drer\adgrb2, Drer\adgrf3b, Drer\adgrf6, Drer\adgrb3, Drer\adgrf8, Drer\adgrf3a, Drer\adgrb1a, Drer\adgrd2, Drer\adgrg6" - "Cele\srh-291, Cele\lat-2" Xtro\gpr157 "Mmus\Adgrb1, Mmus\Adgre1, Mmus\Adgrf2, Mmus\Adgrf4, Mmus\Adgrf5, Mmus\Adgrb3, Mmus\Adgrf3, Mmus\Adgrb2, Mmus\Adgrf1" "Hsap\ADGRF3, Hsap\ADGRF1, Hsap\ADGRD1, Hsap\ADGRB1, Hsap\ADGRF5, Hsap\ADGRF2, Hsap\ADGRB2, Hsap\ADGRB3, Hsap\ADGRD2, Hsap\ADGRF4" viable DRSC08506 K 0.299797719 -0.116957227 -0.568413851 0.567150131 2.238021245 -0.10575659 FBgn0038558 CG12347 - http://flybase.org/reports/FBgn0038558 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12347 - CG12347 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026754 Ugt37c1 UDP-glycosyltransferase 37c1 http://flybase.org/reports/FBgn0026754 FBgn0025831 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 UDP-glycosyltransferase activity ; GO:0008194 | inferred from sequence or structural similarity with UniProtKB:P18569 UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with UniProtKB:P18569 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 integral component of membrane ; GO:0016021 | inferred from sequence model "EG:EG0003.4, AC 004641A, LD15335, DmeUgt37c1, CG8652, Ugt37c1" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG8652 11-Aug-17 DroID_v2017_08 "Drer\ugt1b4, Drer\ugt5b3, Drer\ugt1b3, Drer\zgc:172315, Drer\ugt2b1, Drer\ugt2b6, Drer\ugt2a5, Drer\ugt5b1, Drer\ugt5a5, Drer\ugt8, Drer\ugt5f1, Drer\ugt1ab, Drer\ugt5c1, Drer\ugt2b5, Drer\ugt5d1, Drer\ugt5g1, Drer\ugt5e1, Drer\ugt1b7, Drer\ugt5c3, Drer\ugt5a2, Drer\ugt5a4, Drer\ugt5g2, Drer\ugt2b3, Drer\ugt1b2, Drer\ugt1b5, Drer\ugt2a6, Drer\ugt5a1, Drer\ugt5b2, Drer\ugt5b6, Drer\ugt2a2, Drer\ugt5c2" Scer\ATG26 "Cele\ugt-59, Cele\ugt-49, Cele\ugt-41, Cele\ugt-26, Cele\ugt-39, Cele\ugt-22, Cele\ugt-27, Cele\ugt-5, Cele\ugt-30, Cele\C55H1.1, Cele\ugt-19, Cele\ugt-36, Cele\ugt-48, Cele\ugt-37, Cele\ugt-55, Cele\H23N18.4, Cele\ugt-6, Cele\ugt-20, Cele\ugt-28, Cele\ugt-23, Cele\ugt-51, Cele\ugt-11, Cele\ugt-31, Cele\F10D2.8, Cele\ugt-29, Cele\ugt-32, Cele\ugt-18, Cele\ugt-38, Cele\ugt-60, Cele\ugt-50, Cele\ugt-16, Cele\ugt-53, Cele\ugt-56, Cele\ugt-21, Cele\ugt-61, Cele\ugt-47, Cele\ugt-35, Cele\ugt-52, Cele\ugt-62, Cele\ugt-43, Cele\ugt-34, Cele\ugt-9, Cele\ugt-45, Cele\ugt-54, Cele\ugt-8, Cele\ugt-57, Cele\ugt-46, Cele\ugt-7, Cele\ugt-40, Cele\ugt-12, Cele\K04A8.10, Cele\ugt-3, Cele\ugt-2, Cele\ugt-10, Cele\ugt-44, Cele\ugt-14, Cele\ugt-1, Cele\ugt-17, Cele\ugt-58, Cele\C03A7.12, Cele\Y43D4A.2, Cele\ugt-4, Cele\ugt-33, Cele\ugt-13, Cele\ugt-25, Cele\ugt-15, Cele\ugt-42, Cele\C03A7.13, Cele\C23G10.6, Cele\ugt-24" "Xtro\ugt2a1, Xtro\ugt2b4, Xtro\ugt8, Xtro\ugt3a2, Xtro\ugt1a6" "Mmus\Ugt1a7c, Mmus\Ugt3a2, Mmus\Ugt2b36, Mmus\Ugt2b1, Mmus\Ugt2b37, Mmus\Ugt2a3, Mmus\Ugt2b38, Mmus\Ugt1a6b, Mmus\Ugt1a2, Mmus\Ugt2b5, Mmus\Ugt1a1, Mmus\Ugt1a9, Mmus\Ugt2a1, Mmus\Ugt8a, Mmus\Ugt3a1, Mmus\Ugt2b34, Mmus\Ugt1a5, Mmus\Ugt2b35" "Hsap\UGT3A1, Hsap\UGT1A9, Hsap\UGT2B10, Hsap\UGT2B17, Hsap\UGT1A3, Hsap\UGT2A2, Hsap\UGT8, Hsap\UGT2B15, Hsap\UGT1A10, Hsap\UGT2B28, Hsap\UGT2A3, Hsap\UGT1A6, Hsap\UGT2B11, Hsap\UGT1A4, Hsap\UGT2B7, Hsap\UGT1A5, Hsap\UGT2B4, Hsap\UGT1A7, Hsap\UGT3A2, Hsap\UGT1A8, Hsap\UGT1A1" viable FBgn0278608 Dsp1 Dorsal switch protein 1 http://flybase.org/reports/FBgn0278608 protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P23497-3 transcription factor binding ; GO:0008134 | inferred from physical interaction with dl TBP-class protein binding ; GO:0017025 | inferred from physical interaction with Tbp DNA binding, bending ; GO:0008301 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay single-stranded DNA binding ; GO:0003697 | non-traceable author statement" "positive regulation of DNA binding ; GO:0043388 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from mutant phenotype negative regulation of antimicrobial humoral response ; GO:0008348 | inferred from mutant phenotype inferred from genetic interaction with Rel developmental process ; GO:0032502 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay DNA unwinding involved in DNA replication ; GO:0006268 | non-traceable author statement negative regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0017055 | inferred from direct assay segment specification ; GO:0007379 | inferred from mutant phenotype leg disc development ; GO:0035218 | inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement inferred by curator from GO:0000122,GO:0003677 polytene chromosome ; GO:0005700 | inferred from direct assay" "DSP1, Dsp1, dsp1, CG12223, ssrp2, Ssrp2, Hmg14D, hmg, Hmg14B, HMGB1" "IPR017967:HMG box A DNA-binding domain, conserved site, IPR009071:High mobility group box domain" CG12223 11-Aug-17 DroID_v2017_08 "Drer\hmgb1b, Drer\tox, Drer\ubtf, Drer\tfam, Drer\hmgb3b, Drer\hmg20b, Drer\hmgb2a, Drer\hmgb3a, Drer\tox4a, Drer\tox3, Drer\ubtfl, Drer\hmgb1a, Drer\tox4b, Drer\hmgb2b, Drer\hmg20a" "Scer\HMO1, Scer\NHP6B, Scer\ABF2, Scer\NHP10, Scer\NHP6A, Scer\IXR1" "Cele\hmg-1.2, Cele\hmg-1.1, Cele\hmg-20" "Xtro\tox3, Xtro\hmg20b, Xtro\hmgb2, Xtro\tox, Xtro\hmg20a, Xtro\hmgb3, Xtro\ubtf, Xtro\tfam, Xtro\tox2, Xtro\tox4, Xtro\hmgb1" "Mmus\Tox3, Mmus\Gm21596, Mmus\Tox, Mmus\Hmg20b, Mmus\Tox4, Mmus\Hmg20a, Mmus\Tfam, Mmus\Ubtfl1, Mmus\Tox2, Mmus\Hmgb4, Mmus\Hmgb3, Mmus\Ubtf, Mmus\Hmgb1, Mmus\Hmgb2" "Hsap\HMG20A, Hsap\TOX2, Hsap\HMG20B, Hsap\HMGB4, Hsap\TOX4, Hsap\UBTF, Hsap\HMGB1, Hsap\HMGB2, Hsap\TOX3, Hsap\TOX, Hsap\HMGB3, Hsap\TFAM" "visible,neuroanatomy defective,lethal,flight defective,recessive,sterile,partially,fertile,poor,homeotic,viable,locomotor behavior defective,wild-type" "wing,scutellum,adult thorax,dorsal,eye,intersegmental nerve,anterior fascicle & synapse,haltere,egg,abdominal 5 ventral denticle belt,abdominal 4 ventral denticle belt,embryonic/first instar larval cuticle,prothoracic leg,metathoracic leg,ectopic,sex comb,metathoracic laterotergite,scutum,adult abdominal segment 6,adult abdominal segment 5,adult abdominal segment 4,abdominal sternite bristle,metathoracic segment,anterior compartment" DRSC23078 K -1.782546655 -1.832569564 FBgn0040959 Peritrophin-15a Peritrophin-15a http://flybase.org/reports/FBgn0040959 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from sequence or structural similarity chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular space ; GO:0005615 | inferred from sequence or structural similarity "CG17814, CT39472, Dm15a, Peritrophin-15a, peritrophin-15a" IPR002557:Chitin binding domain CG17814 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0045962 Stalker\ORF1 Stalker element ORF1 http://flybase.org/reports/FBgn0045962 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - Stalker\ORF1 "IPR026523:Paraneoplastic antigen Ma, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain, IPR015416:Zinc finger, H2C2-type, histone UAS binding" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037684 CG8129 - http://flybase.org/reports/FBgn0037684 protein_coding_gene - - - "CT24308, CG8129" IPR001926:Tryptophan synthase beta subunit-like PLP-dependent enzyme CG8129 11-Aug-17 DroID_v2017_08 "Drer\sdsl, Drer\si:ch73-263o4.4, Drer\LOC100331665" "Scer\SRY1, Scer\CHA1, Scer\ILV1" "Cele\K01C8.1, Cele\T01H8.2, Cele\Y51H7C.9" "Xtro\sds, Xtro\srr, Xtro\sdsl" "Mmus\Sdsl, Mmus\Srr, Mmus\Sds" "Hsap\SRR, Hsap\SDSL, Hsap\SDS" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0265276 l(3)neo38 lethal (3) neo38 http://flybase.org/reports/FBgn0265276 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000003381" regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 heterochromatin ; GO:0000792 | inferred from direct assay "l(3)neo38, CG6930, CG14725, CG31364, BcDNA:SD16005, anon2F4, anon-EST:fe2F4" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027775:C2H2- zinc finger protein family subset, IPR013087:Zinc finger C2H2-type" CG6930 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-66i24.8, Drer\LOC101882293" Scer\RPN4 "Cele\che-1, Cele\M03D4.4" Xtro\znf605 "Mmus\Zfp369, Mmus\Zkscan17, Mmus\Zfp174, Mmus\Zfp446, Mmus\Zscan5b, Mmus\Zfp444, Mmus\Zfp316, Mmus\Zbtb41, Mmus\Zscan29, Mmus\Zfp110, Mmus\Zfp202, Mmus\Zkscan2, Mmus\Zkscan6, Mmus\Zfp641, Mmus\Zscan18" "Hsap\ZNF496, Hsap\ZSCAN5A, Hsap\PEG3, Hsap\ZBTB12, Hsap\ZNF641, Hsap\ZNF316, Hsap\ZSCAN5B, Hsap\SP3, Hsap\ZNF446, Hsap\ZNF18, Hsap\ZSCAN32, Hsap\ZNF174, Hsap\ZBTB41, Hsap\ZNF444, Hsap\ZSCAN1, Hsap\ZSCAN18, Hsap\ZSCAN29, Hsap\ZNF202, Hsap\ZKSCAN2, Hsap\ZBTB7B" FBgn0039544 CG12877 - http://flybase.org/reports/FBgn0039544 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 - - "BcDNA:LD30051, CG12877" "IPR012337:Ribonuclease H-like domain, IPR013520:Exonuclease, RNase T/DNA polymerase III, IPR031736:Elongin A binding-protein 1" CG12877 11-Aug-17 DroID_v2017_08 "Drer\zgc:152968, Drer\rexo1" "Scer\REX3, Scer\RNH70" "Cele\pqe-1, Cele\Y56A3A.33, Cele\C05C8.5" "Xtro\rexo1, Xtro\LOC100036702, Xtro\LOC100158551" "Mmus\2610020H08Rik, Mmus\Rexo1" "Hsap\LOC81691, Hsap\REXO1, Hsap\LOC100288562, Hsap\LOC101929627" "viable,fertile" FBgn0052567 CG32567 - http://flybase.org/reports/FBgn0052567 protein_coding_gene - - - CG32567 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053382 5SrRNA:CR33382 5SrRNA:CR33382 http://flybase.org/reports/FBgn0053382 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33382, 5SrRNA:CR33382" - CR33382 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065385 l(2)SH1637 lethal (2) SH1637 http://flybase.org/reports/FBgn0065385 gene - - - "l(2)SH1637, l(2)SH2 1637" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267281 CR45717 - http://flybase.org/reports/FBgn0267281 non_protein_coding_gene - - - CR45717 - CR45717 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038682 CG5835 - http://flybase.org/reports/FBgn0038682 protein_coding_gene - - - CG5835 - CG5835 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0000262 cau cauliflower http://flybase.org/reports/FBgn0000262 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available cau - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/larval midgut,embryonic/first instar larval cuticle,embryonic Malpighian tubule" FBgn0032138 CG4364 - http://flybase.org/reports/FBgn0032138 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000259535 "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000463 | inferred from sequence or structural similarity with UniProtKB:O00541 neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000463 | inferred from biological aspect of ancestor with PANTHER:PTN000259535" nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with UniProtKB:O00541 PeBoW complex ; GO:0070545 | inferred from biological aspect of ancestor with PANTHER:PTN000259535 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:O00541 CG4364 "IPR001357:BRCT domain, IPR010613:Pescadillo" CG4364 11-Aug-17 DroID_v2017_08 Drer\pes Scer\NOP7 Cele\lpd-7 Xtro\pes1 Mmus\Pes1 Hsap\PES1 "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0069110 mus314 mutagen-sensitive 314 http://flybase.org/reports/FBgn0069110 gene - - - mus314 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0037114 Cpr78E Cuticular protein 78E http://flybase.org/reports/FBgn0037114 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:LP06027, Cpr78E, CG7160, DmelCpr78E, Cpi78E" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG7160 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\H2-K1, Mmus\2410137M14Rik" - "viable,visible" trichogen cell FBgn0260601 2L1710 - http://flybase.org/reports/FBgn0260601 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1710 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0031872 ihog interference hedgehog http://flybase.org/reports/FBgn0031872 protein_coding_gene "heparin binding ; GO:0008201 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q02936 hedgehog family protein binding ; GO:0097108 | inferred from physical interaction with ptc, hh protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with hh" negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with Dl smoothened signaling pathway ; GO:0007224 | inferred from direct assay smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype regulation of smoothened signaling pathway ; GO:0008589 | inferred from genetic interaction with boi wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from genetic interaction with boi compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from genetic interaction with boi regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from genetic interaction with boi wing disc pattern formation ; GO:0035222 | inferred from genetic interaction with boi cell surface ; GO:0009986 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "CG9211, CT26314, ihog, Ihog, iHog" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR032988:Interference hedgehog" CG9211 11-Aug-17 DroID_v2017_08 "Drer\boc, Drer\cdon" - - "Xtro\fcgr1, Xtro\LOC100496351, Xtro\pecam1, Xtro\LOC100489139, Xtro\LOC100486104, Xtro\cdon, Xtro\fcrl3, Xtro\siglec1, Xtro\boc" "Mmus\Mybpc1, Mmus\Cdon, Mmus\Pxdn, Mmus\Boc" "Hsap\BOC, Hsap\MYBPC1, Hsap\CDON" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,rescuable maternal effect,some die during P-stage" "denticle belt,maternal effect,wing,chaeta,supernumerary" FBgn0039366 CG17198 - http://flybase.org/reports/FBgn0039366 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG17198 "IPR001594:Palmitoyltransferase, DHHC domain" CG17198 11-Aug-17 DroID_v2017_08 "Drer\zdhhc23a, Drer\zdhhc23b, Drer\zdhhc14, Drer\zdhhc20b, Drer\zdhhc5b, Drer\zdhhc18a, Drer\zdhhc20a, Drer\zdhhc3a, Drer\zdhhc12a, Drer\zdhhc24, Drer\zdhhc1, Drer\LOC100334198, Drer\zdhhc7, Drer\zdhhc12b, Drer\zdhhc8b, Drer\zgc:77880, Drer\zdhhc22, Drer\zdhhc5a, Drer\zdhhc3b, Drer\zdhhc21, Drer\zdhhc9" "Scer\ERF2, Scer\PFA5" "Cele\dhhc-9, Cele\dhhc-1, Cele\dhhc-10, Cele\dhhc-12" "Xtro\zdhhc24, Xtro\zdhhc14, Xtro\zdhhc1, Xtro\zdhhc8, Xtro\dnz1, Xtro\zdhhc3, Xtro\zdhhc12, Xtro\zdhhc21, Xtro\zdhhc9, Xtro\zdhhc7" "Mmus\Zdhhc11, Mmus\Zdhhc14, Mmus\Zdhhc7, Mmus\Zdhhc8, Mmus\Zdhhc19, Mmus\Zdhhc5, Mmus\Zdhhc20, Mmus\Zdhhc21, Mmus\Zdhhc1, Mmus\Zdhhc18, Mmus\Zdhhc4, Mmus\Zdhhc12, Mmus\Zdhhc3, Mmus\Zdhhc24, Mmus\Zdhhc22, Mmus\Zdhhc23, Mmus\Zdhhc25, Mmus\Zdhhc9" "Hsap\ZDHHC3, Hsap\ZDHHC11, Hsap\ZDHHC18, Hsap\ZDHHC5, Hsap\ZDHHC1, Hsap\ZDHHC14, Hsap\ZDHHC23, Hsap\ZDHHC19, Hsap\ZDHHC4, Hsap\ZDHHC9, Hsap\ZDHHC20, Hsap\ZDHHC22, Hsap\ZDHHC12, Hsap\ZDHHC21, Hsap\ZDHHC24, Hsap\ZDHHC8, Hsap\ZDHHC7" viable FBgn0259167 CG42272 - http://flybase.org/reports/FBgn0259167 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32415, CG42272, CG32416" IPR015943:WD40/YVTN repeat-like-containing domain CG42272 11-Aug-17 DroID_v2017_08 - "Scer\VPS62, Scer\TDA6" - - - - DRSC22502 IE -2.240561608 -2.319809199 -1.697546794 -1.911550338 0.007429552 0.77011531 FBgn0020390 P-25 P-25 http://flybase.org/reports/FBgn0020390 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available P-25 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037908 dpr5 defective proboscis extension response 5 http://flybase.org/reports/FBgn0037908 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG5308, Dpr-5, CT16895, dpr5, Dpr5" "IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype" CG5308 11-Aug-17 DroID_v2017_08 "Drer\igsf9bb, Drer\lrit3b, Drer\dscama, Drer\LOC100333196, Drer\kirrelb, Drer\kirrel3b, Drer\si:ch211-163c2.2, Drer\kirrel3a, Drer\si:ch211-264f5.6, Drer\si:ch1073-459j12.1, Drer\si:ch211-66e2.3, Drer\lrit3a, Drer\ncam1b, Drer\si:dkey-65b12.12, Drer\ush2a, Drer\lrit1a, Drer\lrit1b, Drer\kirrel3l, Drer\LOC101885444, Drer\kirrela, Drer\sdk1a, Drer\sdk1b, Drer\itgb4, Drer\LOC101885725, Drer\igsf9a, Drer\paplna" - "Cele\zig-8, Cele\zig-1" "Xtro\nfasc, Xtro\obsl1, Xtro\lrit3, Xtro\kirrel2, Xtro\igsf9b, Xtro\papln" "Mmus\Amica1, Mmus\Lrit1, Mmus\Sdk1, Mmus\Kirrel3, Mmus\Lrit3, Mmus\Ptprq, Mmus\Kirrel2, Mmus\Papln, Mmus\Igsf9b, Mmus\Kirrel" "Hsap\SDK1, Hsap\LRIT1, Hsap\KIRREL, Hsap\USH2A, Hsap\CADM4, Hsap\KIRREL2, Hsap\CADM2, Hsap\KIRREL3, Hsap\IGSF9B, Hsap\CADM3, Hsap\PAPLN, Hsap\LRIT3, Hsap\CADM1" viable FBgn0051091 CG31091 - http://flybase.org/reports/FBgn0051091 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - "CG31091, CG5990" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG31091 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH1, Scer\TGL1, Scer\YEH2" "Cele\lipl-4, Cele\lipl-5, Cele\lipl-3, Cele\lipl-8, Cele\lipl-1, Cele\lipl-7, Cele\lipl-6, Cele\lipl-2" Xtro\lipa "Mmus\Lipo1, Mmus\Lipo2, Mmus\Lipn, Mmus\Lipa, Mmus\Lipm, Mmus\Lipo4, Mmus\Lipf, Mmus\Lipo3, Mmus\Lipk" "Hsap\LIPM, Hsap\LIPN, Hsap\LIPJ, Hsap\LIPK, Hsap\LIPF, Hsap\LIPA" viable FBgn0027632 ms(1)287 ms(1)287 http://flybase.org/reports/FBgn0027632 - gene - - - ms(1)287 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0038150 yellow-e3 yellow-e3 http://flybase.org/reports/FBgn0038150 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG17045, yellow-e3, yel-e3, e3" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG17045 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\C24H12.1, Cele\T27A1.3, Cele\F49E11.8, Cele\fbxa-76" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 viable FBgn0032499 Uvrag UV-resistance associated gene http://flybase.org/reports/FBgn0032499 protein_coding_gene SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000389174 positive regulation of autophagy ; GO:0010508 | inferred from electronic annotation with InterPro:IPR018791 negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype positive regulation of receptor-mediated endocytosis ; GO:0048260 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with mam inferred from genetic interaction with N neuron remodeling ; GO:0016322 | inferred from mutant phenotype SNARE complex assembly ; GO:0035493 | inferred from biological aspect of ancestor with PANTHER:PTN000389174 autophagosome maturation ; GO:0097352 | NOT inferred from mutant phenotype endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000389174 lytic vacuole ; GO:0000323 | inferred from biological aspect of ancestor with PANTHER:PTN000389174 "CG6116, UVRAG, Uvrag, Vps38, uvrag, dUVRAG" IPR018791:UV radiation resistance protein/autophagy-related protein 14 CG6116 11-Aug-17 DroID_v2017_08 Drer\uvrag Scer\VPS38 "Cele\Y34B4A.2, Cele\T23G11.7" Xtro\uvrag Mmus\Uvrag Hsap\UVRAG "lethal - all die before end of P-stage,increased cell number,somatic clone,viable,lethal - all die before end of larval stage,male limited,recessive,some die during larval stage,eye color defective" "follicle cell,somatic clone,male genitalia,embryonic/larval fat body,nutrition conditional,autolysosome | wandering third instar larval stage | nutrition conditional,eye,major mitochondrial derivativenos.PG, nos.UTR.THsimVP16, otu.THsimVP16" FBgn0250872 pio::tor - http://flybase.org/reports/FBgn0250872 engineered_fusion_gene - - - pio::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267206 CR45646 - http://flybase.org/reports/FBgn0267206 non_protein_coding_gene - - - CR45646 - CR45646 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065149 l(3)SH075 lethal (3) SH075 http://flybase.org/reports/FBgn0065149 gene - - - "l(3)SH075, l(2)SH3 075" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060306 l(3)S148316b lethal (3) S148316b http://flybase.org/reports/FBgn0060306 gene - - - "1483/16, l(3)S148316b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0085816 CR41606 - http://flybase.org/reports/FBgn0085816 rRNA_gene - - - CR41606 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036184 PCID2 PCI domain-containing protein 2 http://flybase.org/reports/FBgn0036184 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000296424 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9U1H9 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN000296424 mRNA export from nucleus ; GO:0006406 | inferred from direct assay nuclear retention of pre-mRNA at the site of transcription ; GO:0071033 | inferred from biological aspect of ancestor with PANTHER:PTN000296424 poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from biological aspect of ancestor with PANTHER:PTN000296424 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from biological aspect of ancestor with PANTHER:PTN000296424 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery ; GO:0000973 | inferred from biological aspect of ancestor with PANTHER:PTN000296424 transcriptionally active chromatin ; GO:0035327 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN000296424 polysome ; GO:0005844 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay transcription export complex 2 ; GO:0070390 | inferred from direct assay nuclear pore ; GO:0005643 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN000296424 "CG7351, dmPCID2, PCID2" "IPR000717:Proteasome component (PCI) domain, IPR021184:Tumour necrosis factor, conserved site" CG7351 11-Aug-17 DroID_v2017_08 Drer\pcid2 "Scer\YJR084W, Scer\THP1" Cele\C27F2.10 Xtro\pcid2 Mmus\Pcid2 Hsap\PCID2 "viable,female fertile" DRSC10822 K 1.446624442 0.680635261 0.014607143 0.115223299 -1.718500321 0.10188268 FBgn0259173 corn cornetto http://flybase.org/reports/FBgn0259173 protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with insc positive regulation of exocytosis ; GO:0045921 | inferred from mutant phenotype cell cortex ; GO:0005938 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with jar cytoplasm ; GO:0005737 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "corn, CG42278, CG32386, CG8621, CG32390" - CG42278 11-Aug-17 DroID_v2017_08 - - Cele\rsr-1 - Mmus\Srrm1 Hsap\SRRM1 FBgn0031696 Bub1 Bub1 kinase http://flybase.org/reports/FBgn0031696 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from biological aspect of ancestor with PANTHER:PTN000361607" "meiotic sister chromatid cohesion, centromeric ; GO:0051754 | inferred from biological aspect of ancestor with PANTHER:PTN000361607 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from direct assay" centrosome ; GO:0005813 | colocalizes_with inferred from direct assay condensed nuclear chromosome kinetochore ; GO:0000778 | inferred from biological aspect of ancestor with PANTHER:PTN000361607 "Bub1, BUB1, CG14030/Bub1, BUB1-like, CG14030, bub1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013212:Mad3/Bub1 homology region 1, IPR015661:Mitotic spindle checkpoint protein Bub1/Mad3, IPR017441:Protein kinase, ATP binding site, IPR011990:Tetratricopeptide-like helical domain" CG14030 11-Aug-17 DroID_v2017_08 "Drer\bub1bb, Drer\bub1, Drer\bub1ba" "Scer\BUB1, Scer\MAD3" "Cele\san-1, Cele\bub-1" Xtro\bub1 "Mmus\Bub1b, Mmus\Bub1" "Hsap\BUB1, Hsap\BUB1B" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0020059 E(w[a])705 E(w[a])705 http://flybase.org/reports/FBgn0020059 - gene - - - "E705, E(w[a])705" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0000695 fltA flight defective A http://flybase.org/reports/FBgn0000695 - gene - - - fltA - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0036070 CG8072 - http://flybase.org/reports/FBgn0036070 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model CG8072 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG8072 11-Aug-17 DroID_v2017_08 "Drer\glipr2, Drer\crispld2, Drer\crispld1a, Drer\crispld1b, Drer\LOC100536500, Drer\glipr1b, Drer\pi15b, Drer\pi15a, Drer\glipr2l, Drer\r3hdml" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\scl-23, Cele\scl-6, Cele\scl-25, Cele\vap-2, Cele\scl-26, Cele\scl-27, Cele\scl-1, Cele\scl-20, Cele\scl-24, Cele\scl-10" "Xtro\crispld2, Xtro\crisp3, Xtro\MGC108118, Xtro\crisp2, Xtro\glipr2, Xtro\r3hdml, Xtro\crisp1" "Mmus\Clec18a, Mmus\Crisp1, Mmus\Crispld1, Mmus\Glipr1, Mmus\Glipr1l1, Mmus\Glipr2, Mmus\Pi15, Mmus\Crisp2, Mmus\Crisp3, Mmus\Pi16, Mmus\Glipr1l2, Mmus\Crispld2, Mmus\R3hdml, Mmus\Crisp4" "Hsap\GLIPR2, Hsap\CRISP2, Hsap\CRISP3, Hsap\CLEC18A, Hsap\CLEC18B, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\PI16, Hsap\R3HDML, Hsap\PI15, Hsap\GLIPR1, Hsap\CRISPLD1, Hsap\CRISPLD2, Hsap\CRISP1" viable DRSC10960 K 0.040563154 -0.387554011 -0.392544461 0.47869815 1.569390645 1.26807552 FBgn0014254 l(2)DB1 lethal (2) DB1 http://flybase.org/reports/FBgn0014254 - gene - - - "DB1, l(2)DB1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030559 CG13404 - http://flybase.org/reports/FBgn0030559 protein_coding_gene - - - CG13404 IPR019319:Protein of unknown function DUF2368 CG13404 11-Aug-17 DroID_v2017_08 Drer\plgrkt - "Cele\tag-281, Cele\tag-280" Xtro\plgrkt Mmus\Plgrkt Hsap\PLGRKT viable FBgn0036441 CG13476 - http://flybase.org/reports/FBgn0036441 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13476 - CG13476 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0065942 l(2)SH0114 lethal (2) SH0114 http://flybase.org/reports/FBgn0065942 gene - - - "l(2)SH0114, l(2)SH2 0114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040911 CG12683 - http://flybase.org/reports/FBgn0040911 protein_coding_gene - - - CG12683 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038632 CG14301 - http://flybase.org/reports/FBgn0038632 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14301 IPR002557:Chitin binding domain CG14301 11-Aug-17 DroID_v2017_08 "Drer\zgc:103586, Drer\cda" - "Cele\cdd-1, Cele\cdd-2, Cele\Y56A3A.6" - "Mmus\Maged2, Mmus\Cda, Mmus\Maged1, Mmus\Tro, Mmus\Gm15114" "Hsap\MAGED2, Hsap\TRO, Hsap\CDA, Hsap\MAGED4, Hsap\MAGED1, Hsap\MAGED4B" "viable,fertile" FBgn0039674 CG1907 - http://flybase.org/reports/FBgn0039674 protein_coding_gene oxoglutarate:malate antiporter activity ; GO:0015367 | inferred from sequence or structural similarity with UniProtKB:Q02978 oxoglutarate:malate antiporter activity ; GO:0015367 | inferred from biological aspect of ancestor with PANTHER:PTN001942042 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 malate transport ; GO:0015743 | inferred from sequence or structural similarity with UniProtKB:Q02978 alpha-ketoglutarate transport ; GO:0015742 | inferred from sequence or structural similarity with UniProtKB:Q02978 mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:Q02978 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001942042 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q02978 mitochondrion ; GO:0005739 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 lipid particle ; GO:0005811 | inferred from direct assay "CG1907, CG 1907" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG1907 11-Aug-17 DroID_v2017_08 "Drer\ucp2, Drer\slc25a10, Drer\slc25a35, Drer\slc25a34, Drer\mrpl12, Drer\slc25a11, Drer\slc25a14, Drer\si:ch1073-100f3.2" "Scer\OAC1, Scer\DIC1" "Cele\mrpl-12, Cele\ucp-4, Cele\slc-25A10, Cele\misc-1" "Xtro\slc25a10, Xtro\slc25a27, Xtro\rangrf, Xtro\slc25a30, Xtro\ucp1, Xtro\ucp2, Xtro\slc25a11" "Mmus\Ucp3, Mmus\Ucp2, Mmus\Slc25a30, Mmus\Slc25a27, Mmus\Slc25a35, Mmus\Slc25a10, Mmus\Mrpl12, Mmus\Slc25a34, Mmus\Ucp1, Mmus\Slc25a14, Mmus\Slc25a11" "Hsap\SLC25A14, Hsap\UCP1, Hsap\SLC25A34, Hsap\SLC25A30, Hsap\UCP3, Hsap\SLC25A11, Hsap\MRPL12, Hsap\SLC25A35, Hsap\SLC25A27, Hsap\UCP2, Hsap\SLC25A10" "viable,planar polarity defective" FBgn0021845 l(2)k14810 lethal (2) k14810 http://flybase.org/reports/FBgn0021845 - gene - - - l(2)k14810 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0085549 CG40973 - http://flybase.org/reports/FBgn0085549 protein_coding_gene - - - CG40973 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264903 CG44094 - http://flybase.org/reports/FBgn0264903 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44094 - CG44094 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032281 CG17107 - http://flybase.org/reports/FBgn0032281 protein_coding_gene - - - CG17107 - CG17107 11-Aug-17 DroID_v2017_08 - - Cele\nlp-24 - - - viable DRSC02575 K -0.330602205 0.733076153 -0.068607194 0.066521052 -1.651889198 -0.475095495 FBgn0026176 SkpB SKP1-related B http://flybase.org/reports/FBgn0026176 FBgn0033684 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000002736 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with SGD:S000002736 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with SGD:S000002736 "CG8881, dskpB, Skp, SkpB, skpB" "IPR011333:SKP1/BTB/POZ domain, IPR001232:S-phase kinase-associated protein 1-like, IPR016072:SKP1 component, dimerisation, IPR016073:SKP1 component, POZ domain, IPR016897:S-phase kinase-associated protein 1" CG8881 11-Aug-17 DroID_v2017_08 Drer\skp1 "Scer\SKP1, Scer\ELC1" "Cele\skr-19, Cele\skr-21, Cele\skr-17, Cele\skr-4, Cele\skr-10, Cele\skr-15, Cele\skr-2, Cele\skr-1, Cele\skr-8, Cele\skr-12, Cele\skr-7, Cele\skr-9, Cele\skr-6, Cele\skr-5, Cele\skr-13, Cele\skr-14, Cele\skr-16, Cele\skr-20, Cele\skr-18, Cele\skr-3" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 "viable,visible,planar polarity defective" mesothoracic tergum FBgn0003928 snRNA:U3:95C small nuclear RNA U3 at 95C http://flybase.org/reports/FBgn0003928 FBgn0003925 snRNA_gene - - - "snRNA[[2]], K7, snRNA:U3, snRNA3, snRNA2, U3snRNA95C, U3snRNA, snRNA:U3:95C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085776 CR40855 - http://flybase.org/reports/FBgn0085776 non_protein_coding_gene - - - CR40855 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005265 l(3)SG85 lethal (3) SG85 http://flybase.org/reports/FBgn0005265 - gene - - - l(3)SG85 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0265497 CR44366 - http://flybase.org/reports/FBgn0265497 non_protein_coding_gene - - - CR44366 - CR44366 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004797 mdy midway http://flybase.org/reports/FBgn0004797 "FBgn0032608, FBgn0032610, FBgn0032611, FBgn0051991" protein_coding_gene diacylglycerol O-acyltransferase activity ; GO:0004144 | inferred from direct assay triglyceride biosynthetic process ; GO:0019432 | inferred from electronic annotation with InterPro:IPR027251 regulation of nurse cell apoptotic process ; GO:0045477 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from genetic interaction with Bx negative regulation of lipid storage ; GO:0010888 | inferred from direct assay oogenesis ; GO:0048477 | inferred from mutant phenotype - "CT39962, CG17938, CG17937, CG13273, CG31991, mdy, Dgat1, DGAT, DGAT1, Mdy, mdcds_3562" "IPR004299:Membrane bound O-acyl transferase, MBOAT, IPR014371:Sterol O-acyltransferase, ACAT/DAG/ARE types, IPR027251:Diacylglycerol O-acyltransferase 1" CG31991 11-Aug-17 DroID_v2017_08 "Drer\soat1, Drer\dgat1a, Drer\dgat1b" "Scer\ARE1, Scer\ARE2" "Cele\mboa-2, Cele\mboa-1" "Xtro\soat2, Xtro\soat1, Xtro\dgat1" "Mmus\Soat2, Mmus\Soat1, Mmus\Dgat1" "Hsap\SOAT1, Hsap\SOAT2, Hsap\DGAT1" "female sterile,recessive,viable" "salivary gland,lipid particle | ectopicppl.PP,lipid particle | ectopic48Y,nurse cell & nucleus,egg chamber,nurse cell & nuclear membrane" FBgn0001858 l(1)TW3 lethal (1) TW3 http://flybase.org/reports/FBgn0001858 - gene - - - l(1)TW3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female fertile,chemical sensitive,lethal - all die before end of pupal stage,cold sensitive,some die during pupal stage" FBgn0024994 Csat Csat http://flybase.org/reports/FBgn0024994 FBgn0015871 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from electronic annotation with InterPro:IPR007271 UDP-galactose transmembrane transporter activity ; GO:0005459 | inferred from direct assay CMP-N-acetylneuraminate transmembrane transporter activity ; GO:0005456 | NOT inferred from direct assay UDP-xylose transmembrane transporter activity ; GO:0005464 | NOT inferred from direct assay UDP-N-acetylgalactosamine transmembrane transporter activity ; GO:0005463 | inferred from direct assay UDP-glucuronic acid transmembrane transporter activity ; GO:0005461 | NOT inferred from direct assay UDP-N-acetylgalactosamine transport ; GO:0015789 | inferred from direct assay galactose transport ; GO:0015757 | inferred from direct assay UDP-galactose transport ; GO:0015785 | inferred from direct assay CMP-N-acetylneuraminate transport ; GO:0015782 | NOT inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007271 Golgi membrane ; GO:0000139 | inferred from electronic annotation with InterPro:IPR007271 Golgi medial cisterna ; GO:0005797 | inferred from direct assay "UDP-Gal/UDP-GalNAc, CG2675, dNST-2, dNST-1, DmNST, DmUGT, CSAT, ugt, anon-3Bb, EG:100G10.5, Csat" IPR007271:Nucleotide-sugar transporter CG2675 11-Aug-17 DroID_v2017_08 "Drer\slc35a1, Drer\slc35a2, Drer\slc35a4, Drer\slc35a5, Drer\slc35a3b, Drer\slc35a3a" - "Cele\nstp-4, Cele\srf-3, Cele\nstp-7, Cele\nstp-8, Cele\nstp-6, Cele\nstp-5, Cele\ugtp-1, Cele\nstp-3" "Xtro\slc35a3.2, Xtro\slc35a3.1, Xtro\slc35a5, Xtro\slc35a1" "Mmus\Slc35a5, Mmus\Slc35a1, Mmus\Slc35a3, Mmus\Slc35a4, Mmus\Slc35a2, Mmus\Mfsd14a" "Hsap\SLC35A5, Hsap\SLC35A2, Hsap\SLC35A3, Hsap\SLC35A1, Hsap\SLC35A4" "viable,fertile" FBgn0277421 l(3)psg16 - http://flybase.org/reports/FBgn0277421 gene - - - "l(3)psg16, psg16" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011252 ms(3)04202 ms(3)04202 http://flybase.org/reports/FBgn0011252 - gene - - - "ms(3)65E, ms(3)04202" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0265488 BG01340 - http://flybase.org/reports/FBgn0265488 gene - - - BG01340 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085327 CG34298 - http://flybase.org/reports/FBgn0085327 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34298 - CG34298 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-396h14.1, Drer\adam17b, Drer\adam10b, Drer\adam17a" - - "Xtro\adam17, Xtro\adam10" "Mmus\Adam17, Mmus\Adam10" "Hsap\ADAM10, Hsap\ADAM17" FBgn0033536 CG16942 - http://flybase.org/reports/FBgn0033536 protein_coding_gene - - - CG16942 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033353 CG13749 - http://flybase.org/reports/FBgn0033353 protein_coding_gene - - - CG13749 - CG13749 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030833 CG8915 - http://flybase.org/reports/FBgn0030833 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001374, InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 helicase activity ; GO:0004386 | inferred from sequence or structural similarity" RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "cg8915, CG8915" "IPR001374:R3H domain, IPR001650:Helicase, C-terminal, IPR007502:Helicase-associated domain, IPR011545:DEAD/DEAH box helicase domain, IPR011709:Domain of unknown function DUF1605, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain" CG8915 11-Aug-17 DroID_v2017_08 "Drer\dhx29, Drer\tdrd9, Drer\dhx36, Drer\dhx30, Drer\dhx57, Drer\dhx9" Scer\YLR419W Cele\F52B5.3 "Xtro\dhx30, Xtro\dhx29, Xtro\ythdc2, Xtro\dhx9, Xtro\tdrd9, Xtro\dhx36" "Mmus\Dhx57, Mmus\Dhx30, Mmus\Dhx29, Mmus\Dhx9, Mmus\Dhx36, Mmus\Ythdc2, Mmus\Tdrd9" "Hsap\DHX29, Hsap\DHX30, Hsap\TDRD9, Hsap\DHX36, Hsap\DHX57, Hsap\YTHDC2, Hsap\DHX9" viable FBgn0035756 unc-13-4A unc-13-4A http://flybase.org/reports/FBgn0035756 protein_coding_gene - synaptic vesicle priming ; GO:0016082 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000080880 synaptic vesicle ; GO:0008021 | non-traceable author statement "CG14833, CG8608, dunc-13-4A, CG14832, CG14831, CG32381, unc-13-4A, UNC-13-4A" "IPR000008:C2 domain, IPR014770:Munc13 homology 1, IPR014772:Mammalian uncoordinated homology 13, domain 2, IPR015943:WD40/YVTN repeat-like-containing domain" CG32381 11-Aug-17 DroID_v2017_08 "Drer\unc13d, Drer\baiap3" "Scer\TCB3, Scer\TCB1, Scer\INN1, Scer\TCB2" Cele\F54G2.1 Xtro\baiap3 "Mmus\Unc13d, Mmus\Baiap3" "Hsap\BAIAP3, Hsap\UNC13D" viable FBgn0028215 l(3)S008840 lethal (3) S008840 http://flybase.org/reports/FBgn0028215 gene - - - "0088/40, l(3)S008840" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261580 CG42690 - http://flybase.org/reports/FBgn0261580 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42690 - CG42690 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022665 Dep4 Dep4 http://flybase.org/reports/FBgn0022665 - gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "DEP4, Dep4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029002 miple2 midkine and pleiotrophin 2 http://flybase.org/reports/FBgn0029002 protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR020090 heparin binding ; GO:0008201 | inferred from sequence or structural similarity with HGNC:6972 heparin binding ; GO:0008201 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype mesoderm morphogenesis ; GO:0048332 | inferred from biological aspect of ancestor with PANTHER:PTN001078015 extracellular region ; GO:0005576 | inferred from direct assay "Miple2, CG18321, miple2" "IPR020090:Pleiotrophin/Midkine, C-terminal domain" CG18321 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0060765 l(3)S062914b lethal (3) S062914b http://flybase.org/reports/FBgn0060765 gene - - - "0629/14, l(3)S062914b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033348 Spt Spitting Image http://flybase.org/reports/FBgn0033348 protein_coding_gene - cellularization ; GO:0007349 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR008837 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR008837 filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay cleavage furrow ; GO:0032154 | colocalizes_with inferred from direct assay "CG8247, Spt, spt, SPT" IPR008837:Serendipity locus alpha CG8247 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC07123 I 3.438918057 0.555937269 0.425841963 -0.631712712 -0.602673887 -0.501780348 FBgn0030884 CG6847 - http://flybase.org/reports/FBgn0030884 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available CG6847 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6847 11-Aug-17 DroID_v2017_08 "Drer\sco1, Drer\pla1a, Drer\lipib, Drer\lipia, Drer\sco2" - "Cele\C06C3.8, Cele\T10B5.7, Cele\B0454.9, Cele\C14E2.6, Cele\C08A9.6, Cele\C40H1.2, Cele\Y51H4A.5, Cele\C41H7.6, Cele\sco-1, Cele\C41H7.4" "Xtro\pnliprp3, Xtro\pnliprp2, Xtro\LOC100486161, Xtro\pnliprp2, Xtro\liph" "Mmus\Pnlip, Mmus\Lipi, Mmus\Pnliprp2, Mmus\Sco2, Mmus\Sco1, Mmus\Liph, Mmus\Pnliprp1, Mmus\Pla1a" "Hsap\PNLIPRP3, Hsap\PLA1A, Hsap\PNLIPRP2, Hsap\PNLIPRP1, Hsap\SCO2, Hsap\LIPI, Hsap\LIPH, Hsap\SCO1, Hsap\PNLIP" viable FBgn0032136 Apoltp Apolipoprotein lipid transfer particle http://flybase.org/reports/FBgn0032136 protein_coding_gene lipoprotein particle receptor binding ; GO:0070325 | inferred from physical interaction with LpR2 lipid transporter activity ; GO:0005319 | inferred from mutant phenotype positive regulation of lipid transport ; GO:0032370 | inferred from mutant phenotype sterol transport ; GO:0015918 | inferred from mutant phenotype acylglycerol transport ; GO:0034196 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CT39214, CG15828, Apoltp, apoLTP, apoltp, LTP, ApoLTPI, ApoLTPII" "IPR001747:Lipid transport protein, N-terminal, IPR001846:von Willebrand factor, type D domain, IPR009454:Lipid transport, open beta-sheet, IPR011030:Vitellinogen, superhelical, IPR015816:Vitellinogen, beta-sheet N-terminal, IPR015817:Vitellinogen, open beta-sheet, subdomain 1, IPR015819:Lipid transport protein, beta-sheet shell, IPR015255:Vitellinogen, open beta-sheet, IPR014853:Uncharacterised domain, cysteine-rich" CG15828 11-Aug-17 DroID_v2017_08 "Drer\vtg7, Drer\apoba, Drer\apobb.1" - - - Mmus\Apob "Hsap\LOC400499, Hsap\APOB" "embryonic/larval midgut | third instar larval stage,embryonic/larval fat body | third instar larval stage,wing disc | third instar larval stage,embryonic/larval brain | third instar larval stage,embryonic/larval hemolymph | third instar larval stage" FBgn0265058 CR44169 - http://flybase.org/reports/FBgn0265058 non_protein_coding_gene - - - CR44169 - CR44169 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036345 CG17300 - http://flybase.org/reports/FBgn0036345 protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000296496" ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000296496 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from biological aspect of ancestor with PANTHER:PTN000296496" CG17300 "IPR013837:ATP synthase, F0 complex, subunit B" CG17300 11-Aug-17 DroID_v2017_08 Drer\atp5f1 Scer\ATP4 "Cele\asb-1, Cele\asb-2" Xtro\atp5f1 Mmus\Atp5f1 Hsap\ATP5F1 viable FBgn0000230 bsp brown spots http://flybase.org/reports/FBgn0000230 - gene - - - bsp - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female limited,recessive,viable" cuticle FBgn0004678 E(lz) Enhancer of lozenge http://flybase.org/reports/FBgn0004678 - gene - - - E(lz) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259586 B0258 - http://flybase.org/reports/FBgn0259586 gene - - - B0258 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0015971 l(2)CA3 lethal (2) CA3 http://flybase.org/reports/FBgn0015971 - gene - - - l(2)CA3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003431 slrp slow receptor potential http://flybase.org/reports/FBgn0003431 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "hypoD, slrp" - - 11-Aug-17 DroID_v2017_08 - - - - - - neurophysiology defective FBgn0002679 mat(2)syn-G maternal effect syncytial blastoderm arrest G http://flybase.org/reports/FBgn0002679 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)synQF75, mat(2)syn-G" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0036356 CG10222 - http://flybase.org/reports/FBgn0036356 protein_coding_gene GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000477654 RNA polymerase II complex import to nucleus ; GO:0044376 | inferred from biological aspect of ancestor with PANTHER:PTN000477655 neurogenesis ; GO:0022008 | inferred from mutant phenotype RNA polymerase III complex localization to nucleus ; GO:1990022 | inferred from biological aspect of ancestor with PANTHER:PTN000477655 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000477719 CG10222 "IPR030231:GPN-loop GTPase 2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR004130:GPN-loop GTPase" CG10222 11-Aug-17 DroID_v2017_08 Drer\gpn2 Scer\GPN2 Cele\B0207.6 Xtro\gpn2 Mmus\Gpn2 Hsap\GPN2 "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0028094 l(3)S075101 lethal (3) S075101 http://flybase.org/reports/FBgn0028094 gene - - - "0751/01, l(3)S075101" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086695 hd humpty dumpty http://flybase.org/reports/FBgn0086695 protein_coding_gene molecular_function ; GO:0003674 | no biological data available nuclear DNA replication ; GO:0033260 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "fs(3)272-9, l(3)82Fk, l(3)82Ff, CG2669, fs(3)272, hd" IPR024861:Donson CG2669 11-Aug-17 DroID_v2017_08 - - "Cele\C24H12.2, Cele\C24H12.5" Xtro\donson Mmus\Donson "Hsap\DONSON, Hsap\ATP5O" FBgn0261277 rtv retroactive http://flybase.org/reports/FBgn0261277 protein_coding_gene GPI anchor binding ; GO:0034235 | inferred from electronic annotation with InterPro:IPR031424 "positive regulation of voltage-gated potassium channel activity ; GO:1903818 | inferred from electronic annotation with InterPro:IPR031424 sleep ; GO:0030431 | inferred from electronic annotation with InterPro:IPR031424 regulation of synaptic transmission, cholinergic ; GO:0032222 | inferred from electronic annotation with InterPro:IPR031424 chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype regulation of tube architecture, open tracheal system ; GO:0035152 | inferred from mutant phenotype chitin biosynthetic process ; GO:0006031 | inferred from mutant phenotype regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype" - "Rtv, CG1397, rtv, l(1)L1, 1, L1, l(1)G13, l(1)10Ag" IPR031424:Protein quiver CG1397 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030551 CG11674 - http://flybase.org/reports/FBgn0030551 protein_coding_gene - - - CG11674 IPR006149:EB domain CG11674 11-Aug-17 DroID_v2017_08 "Drer\tnfaip6, Drer\megf11, Drer\megf6b, Drer\scarf1, Drer\dkk1a, Drer\dkk2, Drer\ccbe1, Drer\zgc:158328, Drer\megf6a, Drer\esm1, Drer\megf10, Drer\pear1" - Cele\F46F11.7 "Xtro\tnfaip6, Xtro\megf11, Xtro\stab2" "Mmus\Tnfaip6, Mmus\Pear1, Mmus\Megf6, Mmus\Stab1, Mmus\Dkk3, Mmus\Scarf1, Mmus\Dkk2, Mmus\Egfem1, Mmus\Megf10, Mmus\Esm1, Mmus\Megf11" "Hsap\MEGF11, Hsap\TNFAIP6, Hsap\SCARF2, Hsap\SCARF1, Hsap\DKK2, Hsap\PEAR1, Hsap\MEGF10, Hsap\MEGF6" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0265089 eIF4E3 eukaryotic translation initiation factor 4E3 http://flybase.org/reports/FBgn0265089 protein_coding_gene "translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR001040, InterPro:IPR019770 RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor binding ; GO:0031369 | inferred from sequence or structural similarity with HGNC:3287 translation initiation factor activity ; GO:0003743 | contributes_to inferred by curator from GO:0016281 protein binding ; GO:0005515 | inferred from physical interaction with Thor eukaryotic initiation factor 4G binding ; GO:0031370 | inferred from physical interaction with eIF4G1" "translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR001040, InterPro:IPR019770 positive regulation of translation ; GO:0045727 | inferred from mutant phenotype meiotic chromosome condensation ; GO:0010032 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype spermatocyte division ; GO:0048137 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype" eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from physical interaction with eIF4G1 "CG8023, anon-WO0140519.227, eIF4E, l(3)0139, l(3)L0139, elF4E-3, eIF4E3, eIF4E-3" "IPR001040:Translation Initiation factor eIF- 4e, IPR023398:Translation Initiation factor eIF- 4e-like, IPR019770:Eukaryotic translation initiation factor 4E (eIF-4E), conserved site" CG8023 11-Aug-17 DroID_v2017_08 "Drer\eif4e2rs1, Drer\eif4e1b, Drer\eif4ea, Drer\sesn2, Drer\sesn1, Drer\si:zfos-80g12.1, Drer\eif4eb, Drer\eif4e2, Drer\eif4e1c" Scer\CDC33 "Cele\ife-3, Cele\ife-2, Cele\ife-5, Cele\ife-1" "Xtro\eif4e, Xtro\eif4e2, Xtro\eif4e1b, Xtro\sesn3, Xtro\sesn1" "Mmus\Sesn1, Mmus\Sesn3, Mmus\Eif4e2, Mmus\Eif4e1b, Mmus\Eif4e, Mmus\Sesn2" "Hsap\EIF4E1B, Hsap\SESN3, Hsap\SESN2, Hsap\EIF4E2, Hsap\EIF4E, Hsap\SESN1" "lethal,recessive,male sterile,female fertile,meiotic cell cycle defective,male,viable" "sperm individualization complexBSC732),spermatozoon,Nebenkern derivative,pre-elongation spermatid,elongation stage spermatid,seminal vesicle" FBgn0266905 CR45365 - http://flybase.org/reports/FBgn0266905 non_protein_coding_gene - - - CR45365 - CR45365 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267295 CR45731 - http://flybase.org/reports/FBgn0267295 non_protein_coding_gene - - - "lincRNA.624, CR45731" - CR45731 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046638 anon-38D.7 anon-38D.7 http://flybase.org/reports/FBgn0046638 gene - - - "38D.7, anon-38D.7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050074 Obp50d Odorant-binding protein 50d http://flybase.org/reports/FBgn0050074 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG30074, Obp50d, DmelObp50d" IPR006170:Pheromone/general odorant binding protein CG30074 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040231 dac::Ggal\Dach2 Dach2 http://flybase.org/reports/FBgn0040231 engineered_fusion_gene - - - dac::Ggal\Dach2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005150 l(2)G80 lethal (2) G80 http://flybase.org/reports/FBgn0005150 - gene - - - l(2)G80 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024254 aim aimless http://flybase.org/reports/FBgn0024254 - gene - - - aim - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261719 EP1174 - http://flybase.org/reports/FBgn0261719 gene - - - EP1174 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0041189 SSP6107 SSP6107 http://flybase.org/reports/FBgn0041189 gene - - - SSP6107 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036389 ssp2 short spindle 2 http://flybase.org/reports/FBgn0036389 protein_coding_gene - microtubule cytoskeleton organization ; GO:0000226 | inferred from direct assay regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation ; GO:0051455 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay meiotic spindle pole ; GO:0090619 | inferred from direct assay "ssp2, CG9028, Ssp2, sentin" - CG9028 11-Aug-17 DroID_v2017_08 - - - - - - "viable,stress response defective" FBgn0261593 RpS10b Ribosomal protein S10b http://flybase.org/reports/FBgn0261593 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000254423 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "RpS10b, CG14206, M(1)18C, i3, i73, GM19176, CT33819, S10b, M(1)n, M[[n]], l(1)carot13, M(1)36f, Rp S10 b" "IPR005326:Plectin/S10, N-terminal" CG14206 11-Aug-17 DroID_v2017_08 Drer\rps10 "Scer\RPS10B, Scer\RPS10A" Cele\rps-10 Xtro\rps10 "Mmus\Plec, Mmus\Rps10" "Hsap\RPS10-NUDT3, Hsap\PLEC, Hsap\RPS10" DRSC19561 I 0.169516399 -1.649055259 -0.174126838 0.116714775 0.01645748 0.869459086 FBgn0265150 CR44219 - http://flybase.org/reports/FBgn0265150 non_protein_coding_gene - - - CR44219 - CR44219 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051420 CR31420 - http://flybase.org/reports/FBgn0051420 non_protein_coding_gene - - - CR31420 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060888 l(3)S044631 lethal (3) S044631 http://flybase.org/reports/FBgn0060888 gene - - - "0446/31, l(3)S044631" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267061 CR45505 - http://flybase.org/reports/FBgn0267061 non_protein_coding_gene - - - CR45505 - CR45505 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037956 CG6959 - http://flybase.org/reports/FBgn0037956 protein_coding_gene - axonogenesis ; GO:0007409 | inferred from biological aspect of ancestor with PANTHER:PTN000689992 proteinaceous extracellular matrix ; GO:0005578 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 "CT21563, CG6959, 6959" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype" CG6959 11-Aug-17 DroID_v2017_08 "Drer\ogn, Drer\si:ch211-159i8.4, Drer\tpbgl, Drer\zgc:172282, Drer\optc, Drer\lingo3a, Drer\lrtm2a, Drer\lingo2a, Drer\waif2, Drer\lrrc38a, Drer\lrfn2, Drer\lrfn4a, Drer\zmp:0000001073, Drer\lrfn1, Drer\tlr5b, Drer\epyc, Drer\lingo1b, Drer\lrfn5a, Drer\si:ch211-180f4.1, Drer\si:ch211-106k21.5, Drer\lrrc38b, Drer\lrfn5b, Drer\LOC100537897, Drer\tpbgb, Drer\zgc:193598, Drer\lrfn4b, Drer\lingo2b, Drer\zgc:153913, Drer\lrfn2b, Drer\lrrn2, Drer\LOC100535105, Drer\si:ch211-191d15.2, Drer\LOC100151059, Drer\ogmb, Drer\lrtm2b, Drer\lingo1a, Drer\lrrn1" - "Cele\lron-8, Cele\lron-3" Xtro\tpbg "Mmus\Epyc, Mmus\Ogn, Mmus\Lrrn3, Mmus\Tlr9, Mmus\Lingo3, Mmus\Lrrc38, Mmus\Lrfn2, Mmus\Lrfn1, Mmus\Omg, Mmus\Lrfn4, Mmus\Lrrc55, Mmus\Lingo1, Mmus\Tpbgl, Mmus\Lrfn5, Mmus\Tpbg, Mmus\Lrrn2, Mmus\Tlr5, Mmus\Lrrn1, Mmus\Gp5, Mmus\Lingo2, Mmus\Lrfn3" "Hsap\TLR9, Hsap\LINGO2, Hsap\LRRC38, Hsap\LINGO3, Hsap\LRRN3, Hsap\OGN, Hsap\GP5, Hsap\TPBG, Hsap\LRFN5, Hsap\LRRC70, Hsap\OMG, Hsap\LRFN3, Hsap\TPBGL, Hsap\LINGO1, Hsap\LRFN4, Hsap\LRRN1, Hsap\LRRN2, Hsap\TLR5, Hsap\LRFN1, Hsap\EPYC, Hsap\LRFN2, Hsap\LRRC55" FBgn0032921 Mpp6 M-phase phosphoprotein 6 http://flybase.org/reports/FBgn0032921 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000339972 nuclear exosome (RNase complex) ; GO:0000176 | inferred from biological aspect of ancestor with PANTHER:PTN000339972 "MPP6, dMPP6, l(2)k16403, CG9250, BcDNA:RE45276, Mpp6, Mpps, mpp6" IPR019324:M-phase phosphoprotein 6 CG9250 11-Aug-17 DroID_v2017_08 Drer\mphosph6 - Cele\F29A7.6 Xtro\mphosph6 Mmus\Mphosph6 Hsap\MPHOSPH6 "lethal,recessive,wild-type,viable,visible,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum,ganglion mother cell" FBgn0259323 C719.1 - http://flybase.org/reports/FBgn0259323 gene - - - C719.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0037997 CG14742 - http://flybase.org/reports/FBgn0037997 protein_coding_gene - - - "CG14742, DMG8-chr3R.14.009" - CG14742 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016772 anon-70Da anon-70Da http://flybase.org/reports/FBgn0016772 - gene - - - "beta, anon-70Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013311 P\T P element transposase http://flybase.org/reports/FBgn0013311 - transposable_element_gene - - - "A24786, dmTRP, P-element\T, P\T" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , embryonic stage -- adult stage " adult stage && oogenesis stage " ovary

, unfertilized egg

" "non-suppressor of variegation,suppressor of variegation,partially,wild-type,fertile,recessive,reduced,sterile,lethal" FBgn0001305 Kf2 Kynurenine formamidase 2 http://flybase.org/reports/FBgn0001305 - gene arylformamidase activity ; GO:0004061 | inferred from direct assay - - Kf2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036036 CG14174 - http://flybase.org/reports/FBgn0036036 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG14174 IPR027951:Domain of unknown function DUF4477 CG14174 11-Aug-17 DroID_v2017_08 Drer\si:dkey-22a1.3 - - - Mmus\Nepro Hsap\NEPRO "lethal,neuroanatomy defective,viable,visible,body color defective" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0000125 Ars-region3 Autonomous replicating sequence region 3 http://flybase.org/reports/FBgn0000125 - region - - - "PHc700, Ars-region3, Ars3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003628 Su(var)319 Suppressor of variegation 319 http://flybase.org/reports/FBgn0003628 - gene - - - Su(var)319 - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,viable" FBgn0001068 Fs(3)Ton Female sterile (3) Tonuz http://flybase.org/reports/FBgn0001068 - gene - - - "Ton, Fs(3)Tonuz, Fs(3)Sz23, Fs(3)Ton" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" female pronucleus | maternal effect FBgn0065781 l(2)SH0443 lethal (2) SH0443 http://flybase.org/reports/FBgn0065781 gene - - - "l(2)SH0443, l(2)SH2 0443" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011149 l(1)Q225 lethal (1) Q225 http://flybase.org/reports/FBgn0011149 FBgn0010210 gene - - - l(1)Q225 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051698 CG31698 - http://flybase.org/reports/FBgn0051698 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:LP02725, CG31698" - CG31698 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051735 CG31735 - http://flybase.org/reports/FBgn0051735 protein_coding_gene myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT20140, CG31735" "IPR000048:IQ motif, EF-hand binding site" CG31735 11-Aug-17 DroID_v2017_08 Drer\spata17 - - - Mmus\Spata17 Hsap\SPATA17 "viable,visible" mesothoracic tergum FBgn0259476 EP-E - http://flybase.org/reports/FBgn0259476 gene - - - EP-E - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0041841 E(Sev-CycE)E44 E(Sev-CycE)E44 http://flybase.org/reports/FBgn0041841 gene - - - E(Sev-CycE)E44 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025126 su(RpII140[Z36])S20 su(RpII140[Z36])S20 http://flybase.org/reports/FBgn0025126 - gene - - - "Z36[S20], su(RpII140[Z36])S20" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263501 CR43490 - http://flybase.org/reports/FBgn0263501 non_protein_coding_gene - - - CR43490 - CR43490 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065189 l(2)SH2339 lethal (2) SH2339 http://flybase.org/reports/FBgn0065189 gene - - - "l(2)SH2339, l(2)SH2 2339" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085567 CG41239 - http://flybase.org/reports/FBgn0085567 protein_coding_gene - - - CG41239 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001218 Hsc70-3 Heat shock 70-kDa protein cognate 3 http://flybase.org/reports/FBgn0001218 "FBgn0027308, FBgn0027310, FBgn0028286, FBgn0028330, FBgn0029049, FBgn0030335, FBgn0040174, FBgn0044787" protein_coding_gene - regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype sleep ; GO:0030431 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | "Hsc-70-3, hsc3, hsc70-3, dmHsc72, Grp78, Hsc70, BiP, HSC-70, Bip, HSC70, CG4147, HSC3, Hsc3, Hsc3p, hsc70, hsc72, dhsc70, l(1)G0102, l(1)G0111, l(1)G0407, l(1)G0292, l(1)G0341, l(1)G0466, CG1579, anon-WO0138581.7, Hsc70-3, Hsc-3, GRP78, bip, HSC70-3, dBiP, Hsp-c3, A4V4C4_DROME, HSP7C_DROME, dBip" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG4147 11-Aug-17 DroID_v2017_08 "Drer\hsp70.1, Drer\hsp70l, Drer\hspa5, Drer\hspa12b, Drer\hspa13, Drer\hspa14, Drer\si:ch211-199o1.2, Drer\si:dkey-4p15.3, Drer\hspa12a, Drer\hsc70, Drer\hsp70.2, Drer\hspa8" "Scer\SSA3, Scer\KAR2, Scer\SSB2, Scer\SSB1, Scer\SSA2, Scer\SSA4, Scer\SSA1, Scer\LHS1, Scer\SSZ1" "Cele\F44E5.4, Cele\F44E5.5, Cele\hsp-4, Cele\hsp-70, Cele\hsp-3, Cele\hsp-1" "Xtro\hspa2, Xtro\hspa13, Xtro\hspa1l, Xtro\hspa1a, Xtro\hsp70, Xtro\hspa8, Xtro\hspa5, Xtro\hspa12b, Xtro\hspa1b, Xtro\hspa14" "Mmus\Hspa1a, Mmus\Hspa13, Mmus\Hspa12b, Mmus\Hspa1b, Mmus\Hspa14, Mmus\Hspa8, Mmus\Hspa12a, Mmus\Hspa1l, Mmus\Hspa2, Mmus\Hspa5" "Hsap\HSPA5, Hsap\HSPA1L, Hsap\HSPA14, Hsap\HSPA8, Hsap\HSPA2, Hsap\HSPA1A, Hsap\HSPA12A, Hsap\HSPA6, Hsap\HSPA1B, Hsap\HSPA13, Hsap\HSPA12B" "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of embryonic stage,some die during embryonic stage,behavior defective,neuroanatomy defective,dominant" "rhabdomere R7,pupa,third instar larva,adult antennal lobe projection neuron,eye,ommatidium" DRSC20253 K 1.240152423 0.540441277 1.029897444 -1.350018397 2.67489083 3.744226606 FBgn0266976 CR45427 - http://flybase.org/reports/FBgn0266976 non_protein_coding_gene - - - CR45427 - CR45427 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003282 rsc reduplicated sex combs http://flybase.org/reports/FBgn0003282 - gene - - - rsc - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,viable,male,poor,lethal,female,visible" "wing,leg" FBgn0000601 E(var)100C-F Enhancer of variegation 100 http://flybase.org/reports/FBgn0000601 - gene - - - "E(var)100CF, E(var)100, E(var)100C-F" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,enhancer of variegation,dominant" FBgn0027642 l(3)SCEI-1 lethal (3) SCEI-1 http://flybase.org/reports/FBgn0027642 - gene - - - l(3)SCEI-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014023 mRpL47 mitochondrial ribosomal protein L47 http://flybase.org/reports/FBgn0014023 FBgn0063700 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9HD33 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR010729 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9HD33 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "MRP-L47, CG9378, BcDNA:AT29239, mRpL47, Rlc1" "IPR010729:Ribosomal protein L47, mitochondrial" CG9378 11-Aug-17 DroID_v2017_08 Drer\mrpl47 Scer\MRPL4 Cele\mrpl-47 Xtro\mrpl47 Mmus\Mrpl47 Hsap\MRPL47 "viable,visible,body color defective,fertile" "trichogen cell,mesothoracic tergum" FBgn0040722 CG14349 - http://flybase.org/reports/FBgn0040722 protein_coding_gene - - - CG14349 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019938 RpI1 RNA polymerase I subunit http://flybase.org/reports/FBgn0019938 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR015699 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000453524" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083, InterPro:IPR015699" DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN000453524 "153129_at, RPA1, DmRPA1, CG10122, RpI1" "IPR015699:DNA-directed RNA pol I, largest subunit, IPR000722:RNA polymerase, alpha subunit, IPR006592:RNA polymerase, N-terminal, IPR007066:RNA polymerase Rpb1, domain 3, IPR007080:RNA polymerase Rpb1, domain 1, IPR007081:RNA polymerase Rpb1, domain 5, IPR007083:RNA polymerase Rpb1, domain 4" CG10122 11-Aug-17 DroID_v2017_08 Drer\polr1a Scer\RPA190 Cele\rpoa-1 Xtro\polr1a Mmus\Polr1a Hsap\POLR1A "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0044410 Scim17 Sensitized chromosome inheritance modifier 17 http://flybase.org/reports/FBgn0044410 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0267805 CR46130 - http://flybase.org/reports/FBgn0267805 non_protein_coding_gene - - - CR46130 - CR46130 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000289 cg combgap http://flybase.org/reports/FBgn0000289 "FBgn0010639, FBgn0020273, FBgn0033908" protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR027775 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR027775 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "mig, l(2)k11504, CG8367, l(2)07659, cg, Cg" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR027775:C2H2- zinc finger protein family subset" CG8367 11-Aug-17 DroID_v2017_08 "Drer\zgc:175107, Drer\si:ch211-266d19.4, Drer\mtf1, Drer\znf76, Drer\znf574, Drer\LOC100537687, Drer\znf407, Drer\znf410, Drer\mynn, Drer\znf143a, Drer\znf143b" - "Cele\fezf-1, Cele\hbl-1, Cele\Y5F2A.4, Cele\hinf-1, Cele\Y55F3AM.14" "Xtro\znf347, Xtro\zxdc, Xtro\zbtb40, Xtro\znf143, Xtro\zfp64, Xtro\e4f1, Xtro\znf383" "Mmus\Zfp772, Mmus\Zfp408, Mmus\Zfp143, Mmus\Zfp169, Mmus\Zfp786, Mmus\Zfp444, Mmus\Repin1, Mmus\Zfp467, Mmus\Zfp523" "Hsap\ZNF18, Hsap\PRDM15, Hsap\ZNF628, Hsap\ZSCAN32, Hsap\ZNF142, Hsap\ZNF467, Hsap\ZNF442, Hsap\ZNF76, Hsap\ZNF837, Hsap\ZNF425, Hsap\ZNF143, Hsap\ZNF17, Hsap\ZNF444, Hsap\ZNF786, Hsap\ZNF417, Hsap\ZNF697, Hsap\REPIN1" "viable,neuroanatomy defective,fertile,visible,partially lethal - majority die,lethal,recessive,female sterile,hyperplasia,wild-type,dominant" "Kenyon cell,adult mushroom body,wing vein L4,sex comb,supernumerary,wing vein L5,wing vein L2,wing margin,anterior,ventral thoracic disc,prothoracic tibial transverse row bristle,wing,posterior compartment,anterior compartment,prothoracic tibial preapical bristle,wing vein,macrochaeta,leg,antenna,mesothoracic leg,embryonic/larval salivary gland" FBgn0034515 CG13428 - http://flybase.org/reports/FBgn0034515 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13428 - CG13428 11-Aug-17 DroID_v2017_08 - - - - - - DRSC06390 E -0.68535721 0.60343617 3.45120395 0.066861111 -0.250193208 -0.372622061 FBgn0259543 GG01179 - http://flybase.org/reports/FBgn0259543 gene - - - GG01179 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,1st posterior cell,leg,tarsal segment,wing" FBgn0031188 CG14613 - http://flybase.org/reports/FBgn0031188 protein_coding_gene - - - "CT34370, ADP/ATP translocase, CG14613" IPR009688:Domain of unknown function DUF1279 CG14613 11-Aug-17 DroID_v2017_08 "Drer\fam210ab, Drer\fam210aa" - Cele\Y56A3A.22 Xtro\fam210a "Mmus\Fam210b, Mmus\Fam210a" "Hsap\FAM210B, Hsap\FAM210A" FBgn0002165 l(2)Sp9a lethal (2) Sp9a http://flybase.org/reports/FBgn0002165 - gene - - - l(2)Sp9a - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011073 l(1)Q26 lethal (1) Q26 http://flybase.org/reports/FBgn0011073 FBgn0010210 gene - - - l(1)Q26 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267870 CR46158 - http://flybase.org/reports/FBgn0267870 pseudogene_attribute - - - "CR46158, CG12717-related" - CR46158 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040087 p115 p115 http://flybase.org/reports/FBgn0040087 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000000707 vesicle fusion with Golgi apparatus ; GO:0048280 | inferred from electronic annotation with InterPro:IPR006953 Golgi organization ; GO:0007030 | inferred from mutant phenotype Golgi vesicle docking ; GO:0048211 | inferred from biological aspect of ancestor with PANTHER:PTN000000707 transcytosis ; GO:0045056 | inferred from biological aspect of ancestor with PANTHER:PTN000000707 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000000707 membrane fusion ; GO:0061025 | inferred from biological aspect of ancestor with PANTHER:PTN000000707 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000000707 regulation of cell cycle ; GO:0051726 | inferred from direct assay Golgi membrane ; GO:0000139 | inferred from electronic annotation with InterPro:IPR006953 Golgi stack ; GO:0005795 | inferred from direct assay ER to Golgi transport vesicle membrane ; GO:0012507 | inferred from biological aspect of ancestor with PANTHER:PTN000000707 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG1422, dp115, l(1)G0306, p115" "IPR000225:Armadillo, IPR006953:Vesicle tethering protein Uso1/P115-like , head domain, IPR006955:Uso1/p115-like vesicle tethering protein, C-terminal, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG1422 11-Aug-17 DroID_v2017_08 Drer\uso1 Scer\USO1 Cele\uso-1 Xtro\uso1 Mmus\Uso1 Hsap\USO1 "partially lethal - majority die,male,female,recessive,viable,body color defective" "Golgi stack,endoplasmic reticulum,mesothoracic tergum" FBgn0260627 d05123 - http://flybase.org/reports/FBgn0260627 gene - - - d05123 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0082169 p140S p140S http://flybase.org/reports/FBgn0082169 gene - - - "p140, p140S" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053307 CG33307 - http://flybase.org/reports/FBgn0053307 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG16887, BG:DS00941.11, DS00941.11, BcDNA:GH07914, CG33307" - CG33307 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC01349 I 1.440208514 1.826140756 0.634303627 1.426403507 0.193411778 0.179799144 FBgn0003155 psi3 phase angle 3 http://flybase.org/reports/FBgn0003155 - gene - - - "psi 3, psi-3, psi3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eclosion rhythm defective,semidominant" FBgn0041132 l(2)44Fj lethal (2) 44Fj http://flybase.org/reports/FBgn0041132 gene - - - l(2)44Fj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0027645 l(3)CL-L lethal (3) Cell Lethal Left http://flybase.org/reports/FBgn0027645 - gene - - - "CL3L, l(3)CL-L" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001502 l(1)10Ce lethal (1) 10Ce http://flybase.org/reports/FBgn0001502 - gene - - - "16, RA60, l(1)L16, l(1)EF476, l(1)10Ce" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,maternal effect" "egg,germline clone,maternal effect" FBgn0010152 l(3)W lethal (3) W http://flybase.org/reports/FBgn0010152 - gene - - - l(3)W - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032881 CG9319 - http://flybase.org/reports/FBgn0032881 protein_coding_gene alpha-methylacyl-CoA racemase activity ; GO:0008111 | inferred from sequence or structural similarity with HGNC:451 fatty acid alpha-oxidation ; GO:0001561 | non-traceable author statement peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:451 inferred from sequence model "38E.13, CG9319" "IPR003673:CoA-transferase family III, IPR023606:CoA-transferase family III domain" CG9319 11-Aug-17 DroID_v2017_08 Drer\amacr - "Cele\ZK892.4, Cele\C24A3.4" "Xtro\sugct, Xtro\amacr" "Mmus\Sugct, Mmus\Amacr" "Hsap\AMACR, Hsap\SUGCT" FBgn0044057 GTD74-77.3 GTD74-77.3 http://flybase.org/reports/FBgn0044057 gene - - - GTD74-77.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265879 CR44668 - http://flybase.org/reports/FBgn0265879 non_protein_coding_gene - - - "CR44668, lincRNA.594" - CR44668 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266955 CR45406 - http://flybase.org/reports/FBgn0266955 non_protein_coding_gene - - - CR45406 - CR45406 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033988 pcs parcas http://flybase.org/reports/FBgn0033988 protein_coding_gene protein kinase inhibitor activity ; GO:0004860 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 protein kinase inhibitor activity ; GO:0004860 | inferred from sequence or structural similarity with HGNC:10827 SH3 domain binding ; GO:0017124 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from mutant phenotype negative regulation of protein tyrosine kinase activity ; GO:0061099 | inferred from genetic interaction with Btk29A female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype muscle cell fate specification ; GO:0042694 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG7761, prt, pcs" IPR007940:SH3-binding 5 CG7761 11-Aug-17 DroID_v2017_08 "Drer\sh3bp5a, Drer\LOC103909186, Drer\sh3bp5la, Drer\sh3bp5lb, Drer\sh3bp5b" - "Cele\rei-2, Cele\rei-1" "Xtro\sh3bp5l, Xtro\sh3bp5" "Mmus\Sh3bp5, Mmus\Sh3bp5l" "Hsap\SH3BP5L, Hsap\SH3BP5" "viable,grandchildless,cold sensitive" "germline cell,embryonic abdomen,embryonic/first instar larval cuticle,embryonic head,visceral mesoderm,maternal effect,cardiogenic mesoderm,muscle founder cell,presumptive embryonic/larval muscle system,embryonic segment,somatic muscle" FBgn0065890 l(2)SH0220 lethal (2) SH0220 http://flybase.org/reports/FBgn0065890 gene - - - "l(2)SH0220, l(2)SH2 0220" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019892 anon-2Be anon-2Be http://flybase.org/reports/FBgn0019892 - gene - - - "G-42, anon-2Be" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082676 E(ftz)723 E(ftz)723 http://flybase.org/reports/FBgn0082676 gene - - - "723, E(ftz)723" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259252 C155 - http://flybase.org/reports/FBgn0259252 gene - - - C155 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0034218 CG18467 - http://flybase.org/reports/FBgn0034218 protein_coding_gene molecular_function ; GO:0003674 | no biological data available proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000004742 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000004742 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000004742 CG18467 "IPR024964:CTLH/CRA C-terminal to LisH motif domain, IPR006594:LIS1 homology motif, IPR006595:CTLH, C-terminal LisH motif, IPR013144:CRA domain" CG18467 11-Aug-17 DroID_v2017_08 "Drer\gid8b, Drer\gid8a" Scer\GID8 Cele\tag-304 Xtro\gid8 Mmus\Gid8 Hsap\GID8 viable FBgn0053775 CG33775 - http://flybase.org/reports/FBgn0053775 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1034, CG33775" IPR010512:Protein of unknown function DUF1091 CG33775 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262317 mir-966 mir-966 stem loop http://flybase.org/reports/FBgn0262317 miRNA_gene - - - "mir-966, CR43024, miR-966, dme-mir-966, dme-miR-966" - CR43024 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033749 achi achintya http://flybase.org/reports/FBgn0033749 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR008422, InterPro:IPR009057 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay spermatogenesis ; GO:0007283 | inferred from expression pattern inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from expression pattern inferred from mutant phenotype inferred from physical interaction with aly inferred from physical interaction with comr" nucleus ; GO:0005634 | inferred from direct assay "CG8819, zaa, achi, ach, Achi, vis, dTGIFb, achi/vis, dTGIF, TGIF, dTGIFa" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR008422:Homeobox KN domain" CG8819 11-Aug-17 DroID_v2017_08 "Drer\irx6a, Drer\irx2a, Drer\tgif1, Drer\irx5b, Drer\irx3a, Drer\meis3, Drer\irx1a, Drer\irx7, Drer\pknox1.1, Drer\irx5a, Drer\irx3b, Drer\irx1b, Drer\mkxb, Drer\meis1a, Drer\pknox1.2, Drer\irx4a, Drer\mkxa, Drer\pknox2, Drer\meis2a, Drer\meis2b, Drer\irx4b" "Scer\MATALPHA2, Scer\HMLALPHA2, Scer\HMRA2, Scer\TOS8, Scer\CUP9" Cele\psa-3 "Xtro\tgif1, Xtro\irx2, Xtro\tgif2, Xtro\irx1, Xtro\irx3, Xtro\pknox2, Xtro\meis2, Xtro\irx5, Xtro\mkx, Xtro\meis3, Xtro\irx4, Xtro\meis1" "Mmus\Irx4, Mmus\Irx2, Mmus\Meis3, Mmus\Irx1, Mmus\Irx6, Mmus\Pknox2, Mmus\Tgif2lx2, Mmus\Irx3, Mmus\Mkx, Mmus\Tgif1, Mmus\Tgif2lx1, Mmus\Meis1, Mmus\Tgif2, Mmus\Pknox1, Mmus\Irx5, Mmus\Meis2" "Hsap\TGIF2-C20orf24, Hsap\IRX4, Hsap\IRX1, Hsap\MEIS1, Hsap\MEIS2, Hsap\TGIF2, Hsap\IRX5, Hsap\IRX3, Hsap\TGIF2LX, Hsap\MKX, Hsap\TGIF1, Hsap\IRX6, Hsap\PKNOX2, Hsap\TGIF2LY, Hsap\IRX2, Hsap\PKNOX1" " adult stage , embryonic stage -- adult stage " " organism

, testis | restricted

, testis

" " adult stage , embryonic stage , larval stage , adult stage | male " " organism

, dorsal mesothoracic disc

, egg chamber

, testis

, spermatid

, spermatocyte

, ovary

" "viable,fertile,male sterile,partially" FBgn0001186 Hex-A Hexokinase A http://flybase.org/reports/FBgn0001186 FBgn0030140 protein_coding_gene "glucose binding ; GO:0005536 | inferred from electronic annotation with InterPro:IPR001312 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001312, InterPro:IPR019807, InterPro:IPR022672, InterPro:IPR022673 glucokinase activity ; GO:0004340 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 fructokinase activity ; GO:0008865 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 hexokinase activity ; GO:0004396 | inferred from direct assay hexokinase activity ; GO:0004396 | inferred from mutant phenotype mannokinase activity ; GO:0019158 | inferred from biological aspect of ancestor with PANTHER:PTN000455350" carbohydrate phosphorylation ; GO:0046835 | inferred from electronic annotation with InterPro:IPR001312 glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 flight ; GO:0060361 | inferred from mutant phenotype cellular glucose homeostasis ; GO:0001678 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 "HK, CG3001, DM1, HEX, Hex, Hex-A:B, Hex-A,B, Hex-A, HEX-A, HK-A, HexA, hexokinase" "IPR001312:Hexokinase, IPR019807:Hexokinase, binding site, IPR022673:Hexokinase, C-terminal, IPR022672:Hexokinase, N-terminal" CG3001 11-Aug-17 DroID_v2017_08 "Drer\hk1, Drer\gck, Drer\hkdc1, Drer\hk2" "Scer\GLK1, Scer\YLR446W, Scer\EMI2, Scer\HXK2, Scer\HXK1" "Cele\hxk-3, Cele\hxk-2, Cele\hxk-1" "Xtro\hk2, Xtro\gck, Xtro\hk1" "Mmus\Hk3, Mmus\Gck, Mmus\Hkdc1, Mmus\Hk1, Mmus\Hk2" "Hsap\HK2, Hsap\HK1, Hsap\GCK, Hsap\HKDC1, Hsap\HK3" "lethal,recessive,electrophoretic variant,viable" DRSC25354 EK -0.557254235 0.28752464 1.618160829 -0.015664338 -1.539257741 -0.190955184 FBgn0001758 l(1)M8 lethal (1) M8 http://flybase.org/reports/FBgn0001758 - gene - - - l(1)M8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" adult cuticle FBgn0011960 tRNA:Arg-ACG-1-9 transfer RNA:Arginine-ACG 1-9 http://flybase.org/reports/FBgn0011960 "FBgn0003758, FBgn0011947, FBgn0051566, FBgn0060096" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "tRNA[arg], tRNA[Arg][[2]], AE002708.trna63-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002708-b, CR31566, tRNA:arg2:84Fb, chr3R.trna69-ArgACG, tRNA-Arg-ACG-1-9, tRNA:Arg-ACG-1-9, tRNA:R2:84Fb, CGU" - CR31566 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005166 l(2)G560 lethal (2) G560 http://flybase.org/reports/FBgn0005166 - gene - - - l(2)G560 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0084303 2.14.98 2.14.98 http://flybase.org/reports/FBgn0084303 gene - - - 2.14.98 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0032891 Oseg5 Outer segment 5 http://flybase.org/reports/FBgn0032891 protein_coding_gene molecular_function ; GO:0003674 | no biological data available non-motile cilium assembly ; GO:1905515 | inferred from sequence or structural similarity with Oseg1 cilium assembly ; GO:0060271 | inferred from expression pattern cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with MGI:MGI:1915509 non-motile cilium ; GO:0097730 | inferred from direct assay cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:1915509 intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:1915509 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000645840 intraciliary transport particle B ; GO:0030992 | inferred from biological aspect of ancestor with PANTHER:PTN000645840 "CHE-2, OSEG5, CG9333, Oseg5, OSEG, IFT80, Che-2, oseg5" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR011990:Tetratricopeptide-like helical domain, IPR011042:Six-bladed beta-propeller, TolB-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG9333 11-Aug-17 DroID_v2017_08 "Drer\trim59, Drer\ift80" - "Cele\phf-32, Cele\che-2, Cele\fzr-1" Xtro\ift80 "Mmus\Trim59, Mmus\Ift80" "Hsap\IFT80, Hsap\TRIM59" FBgn0086713 bubbles bubbles http://flybase.org/reports/FBgn0086713 gene - - - bubbles - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024740 Lip2 Lipase 2 http://flybase.org/reports/FBgn0024740 FBgn0032288 protein_coding_gene - lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - "lip2, Dmlip2, CG17116, Lip2, dilp2" "IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG17116 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\TGL1, Scer\YEH2, Scer\YEH1" "Cele\lipl-5, Cele\lipl-2, Cele\lipl-6, Cele\lipl-3, Cele\lipl-7, Cele\lipl-8, Cele\lipl-1, Cele\lipl-4" Xtro\lipa "Mmus\Lipo2, Mmus\Lipn, Mmus\Lipm, Mmus\Lipk, Mmus\Lipo3, Mmus\Lipf, Mmus\Lipa, Mmus\Lipo1, Mmus\Lipo4" "Hsap\LIPM, Hsap\LIPA, Hsap\LIPK, Hsap\LIPJ, Hsap\LIPN, Hsap\LIPF" "viable,fertile" DRSC02577 K 0.785376123 0.396735545 -0.457651786 -0.157750348 1.594854519 -0.242949338 FBgn0267903 CG46191 - http://flybase.org/reports/FBgn0267903 protein_coding_gene - sperm chromatin condensation ; GO:0035092 | inferred from electronic annotation with InterPro:IPR024460 - CG46191 IPR024460:Protamine-like CG46191 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264398 FCP-F - http://flybase.org/reports/FBgn0264398 gene - - - FCP-F - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0259789 zld zelda http://flybase.org/reports/FBgn0259789 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with bi transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay "regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay cellularization ; GO:0007349 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from direct assay chromatin ; GO:0000785 | colocalizes_with inferred from direct assay "Zld, CG12701, l(1)G0353, zld, l(1)G0225, l(1)G0427, EP1344, vfl, Vfl, ZLD, VFL, Zelda, zelda" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical, IPR022755:Zinc finger, double-stranded RNA binding" CG12701 11-Aug-17 DroID_v2017_08 - Scer\ZAP1 "Cele\C27A12.2, Cele\sea-2" - - Hsap\ZNF114 FBgn0034661 CG4386 - http://flybase.org/reports/FBgn0034661 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP17, CG4386" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG4386 11-Aug-17 DroID_v2017_08 "Drer\zgc:163079, Drer\ela3l, Drer\f10, Drer\zgc:92041, Drer\zgc:171592, Drer\ctrb1, Drer\zgc:92590, Drer\tmprss4b, Drer\si:ch211-165b19.8, Drer\prss60.1, Drer\LOC100004427, Drer\si:dkeyp-93a5.2, Drer\prss60.2, Drer\si:ch211-165b19.5, Drer\gzm3, Drer\zgc:92511, Drer\gzma, Drer\cfd, Drer\zgc:112368, Drer\prss60.3, Drer\zgc:92313, Drer\zgc:112285, Drer\zgc:112160, Drer\f7i, Drer\prss56, Drer\zgc:153968, Drer\ela2, Drer\zgc:165423, Drer\si:dkey-238d18.3, Drer\gzmk, Drer\zgc:92745, Drer\ela2l, Drer\ovch1, Drer\zgc:154142, Drer\si:ch211-165b19.9, Drer\zgc:112038, Drer\si:dkey-16l2.17, Drer\zgc:123295, Drer\zgc:112302, Drer\try, Drer\LOC562139, Drer\si:dkeyp-93a5.3, Drer\ctrl, Drer\si:dkey-57c15.4, Drer\f7" - "Cele\svh-1, Cele\try-1, Cele\try-6" "Xtro\LOC100135144, Xtro\proz, Xtro\ctrb1, Xtro\cela3a, Xtro\ctrb2, Xtro\cela2a" "Mmus\Tmprss11g, Mmus\Ctrb1, Mmus\Tmprss11c, Mmus\Proz, Mmus\Cela3a, Mmus\Try4, Mmus\Try10, Mmus\Tmprss11e, Mmus\Cela2a, Mmus\2210010C04Rik, Mmus\Tmprss11a, Mmus\Prss2, Mmus\Gm10334, Mmus\F9, Mmus\Klk15, Mmus\Tmprss6, Mmus\Tmprss11d, Mmus\Ctrc, Mmus\Tmprss11f, Mmus\Ctrl, Mmus\Prss3, Mmus\Klk9, Mmus\Tmprss11b, Mmus\Masp1, Mmus\Gm5771, Mmus\Cela3b, Mmus\Cela1, Mmus\Tmprss15, Mmus\Prss1, Mmus\Prss34" "Hsap\TMPRSS15, Hsap\TMPRSS2, Hsap\HPN, Hsap\TMPRSS5, Hsap\PRSS3, Hsap\CELA1, Hsap\CTRL, Hsap\CELA3A, Hsap\KLK9, Hsap\CTRB2, Hsap\PROZ, Hsap\CELA2B, Hsap\CTRB1, Hsap\CELA2A, Hsap\TMPRSS6, Hsap\CELA3B, Hsap\TMPRSS3, Hsap\PRSS1, Hsap\CTRC, Hsap\KLK15, Hsap\MASP1" viable FBgn0058255 CR40255 - http://flybase.org/reports/FBgn0058255 non_protein_coding_gene - - - CR40255 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265524 CR44374 - http://flybase.org/reports/FBgn0265524 non_protein_coding_gene - - - CR44374 - CR44374 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259542 GG01350 - http://flybase.org/reports/FBgn0259542 gene - - - GG01350 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0259299 C717 - http://flybase.org/reports/FBgn0259299 gene - - - C717 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing hair,wing margin,chaeta" FBgn0029568 CG11381 - http://flybase.org/reports/FBgn0029568 protein_coding_gene - - chorion ; GO:0042600 | inferred from direct assay CG11381 - CG11381 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0259384 C275 - http://flybase.org/reports/FBgn0259384 gene - - - C275 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing,wing vein" FBgn0038042 Scgbeta Sarcoglycan beta http://flybase.org/reports/FBgn0038042 protein_coding_gene structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC:10806 muscle organ development ; GO:0007517 | inferred from electronic annotation with InterPro:IPR027659 membrane organization ; GO:0061024 | inferred from biological aspect of ancestor with PANTHER:PTN001080209 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006875, InterPro:IPR027659 sarcoglycan complex ; GO:0016012 | inferred from sequence or structural similarity with HGNC:10806" "Scgbeta, CG5657, DmSCG-beta, dscgbeta, scg-beta" "IPR006875:Sarcoglycan complex subunit protein, IPR027659:Beta-sarcoglycan" CG5657 11-Aug-17 DroID_v2017_08 Drer\sgcb - Cele\sgcb-1 Xtro\sgcb Mmus\Sgcb Hsap\SGCB FBgn0061155 l(2)53Da lethal (2) 53Da http://flybase.org/reports/FBgn0061155 gene - - - "l(2)k05207, l(2)53Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261562 CG42676 - http://flybase.org/reports/FBgn0261562 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42676, CG32317, CG12022, CG13923" - CG42676 11-Aug-17 DroID_v2017_08 - - - - - - DRSC08227 E -0.113685522 0.329132113 1.659188914 -0.869850993 0.167903064 -0.163803597 FBgn0085414 dpr12 defective proboscis extension response 12 http://flybase.org/reports/FBgn0085414 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 synaptic target recognition ; GO:0008039 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG34385, CG14469, Dpr-12, CT34165, dpr12, CG7796, Dpr12" "IPR007110:Immunoglobulin-like domain, IPR003598:Immunoglobulin subtype 2, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype, IPR013098:Immunoglobulin I-set, IPR013106:Immunoglobulin V-set domain" CG34385 11-Aug-17 DroID_v2017_08 "Drer\LOC101885725, Drer\LOC101885444, Drer\LOC100333196, Drer\si:ch211-163c2.2, Drer\si:ch211-264f5.6, Drer\si:dkey-65b12.12" - Cele\zig-8 Xtro\obsl1 Mmus\Amica1 - "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053630 CG33630 - http://flybase.org/reports/FBgn0053630 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12808, CG33630" IPR010512:Protein of unknown function DUF1091 CG33630 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005089 fs(2)OWc1 female sterile (2) OWc1 http://flybase.org/reports/FBgn0005089 - gene - - - fs(2)OWc1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067640 vag vagabond http://flybase.org/reports/FBgn0067640 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available vag - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "oocyte nucleus,germline clone,follicle cell,oocyte" FBgn0085615 CG41325 - http://flybase.org/reports/FBgn0085615 protein_coding_gene - - - CG41325 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000248 cab cabbage http://flybase.org/reports/FBgn0000248 - gene - olfactory learning ; GO:0008355 | traceable author statement - cab - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,tarsal response defective" FBgn0027624 17.6\env 17.6 element env http://flybase.org/reports/FBgn0027624 - transposable_element_gene - - - "17.6\env, env" "IPR012014:Retroelement-encoded protein, env-related, IPR022048:Envelope fusion protein-like" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262564 CR43104 - http://flybase.org/reports/FBgn0262564 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43104, CG43104, mdcds_12891" - CR43104 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065971 l(2)45CDa lethal (2) 45CDa http://flybase.org/reports/FBgn0065971 gene - - - l(2)45CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013750 Arf51F ADP ribosylation factor at 51F http://flybase.org/reports/FBgn0013750 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006689, InterPro:IPR024156 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity NAD(P)+-protein-arginine ADP-ribosyltransferase activity ; GO:0003956 | inferred from direct assay" small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype endosomal transport ; GO:0016197 | traceable author statement myoblast fusion ; GO:0007520 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype protein ADP-ribosylation ; GO:0006471 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle endocytosis ; GO:0048488 | traceable author statement early endosome ; GO:0005769 | inferred from direct assay adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "dArf6, Arf51F, ARF6, AFR51F, Arf6, arf6, Dm Arf51F, LD12493, EP(2)2612, CG8156, Arf51f, dARFIII, ARFIII, ARF3, d-Arf6, arf51F, P40946, arf51f, Arf3" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR024156:Small GTPase superfamily, ARF type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8156 11-Aug-17 DroID_v2017_08 "Drer\arl15a, Drer\arf6a, Drer\arl15b, Drer\arf6b" "Scer\ARF2, Scer\ARF3" "Cele\arf-1.1, Cele\arf-6" "Xtro\arf6, Xtro\arf6.2, Xtro\arl15" "Mmus\Arf6, Mmus\Arl15, Mmus\Arl11" "Hsap\ARL11, Hsap\ARF6, Hsap\ARL15" adult stage head

"chemical sensitive,recessive,chemical resistant,cell shape defective,viable,female sterile,partially,male sterile,cytokinesis defective,male" "embryonic myoblast,ventral nerve cord commissure | embryonic stage,retina,spermatid,primary spermatocyte,cleavage furrow & primary spermatocyte" FBgn0019854 anon-TE7 anon-TE7 http://flybase.org/reports/FBgn0019854 - gene - - - "TE7, anon-TE7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034152 Acp53C14a Accessory gland protein 53C14a http://flybase.org/reports/FBgn0034152 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG8626, Acp53C14a, Acp53Ca, Apc53C14a, Acp53" IPR009392:Drosophila ACP53EA CG8626 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263326 CG43407 - http://flybase.org/reports/FBgn0263326 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43407 - CG43407 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034495 CG11788 - http://flybase.org/reports/FBgn0034495 protein_coding_gene DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000333642 regulation of DNA replication ; GO:0006275 | inferred from sequence or structural similarity with HGNC:24453 maintenance of mitotic sister chromatid cohesion ; GO:0034088 | inferred from biological aspect of ancestor with PANTHER:PTN000333642 regulation of DNA replication ; GO:0006275 | inferred from biological aspect of ancestor with PANTHER:PTN000333642 "Ctf18 RFC-like complex ; GO:0031390 | inferred from biological aspect of ancestor with PANTHER:PTN000333642 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:24453 chromosome, centromeric region ; GO:0000775 | inferred from biological aspect of ancestor with PANTHER:PTN000333642 chromatin ; GO:0000785 | inferred from biological aspect of ancestor with PANTHER:PTN000333642 chromatin ; GO:0000785 | inferred from sequence or structural similarity with HGNC:24453 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN000333642" CG11788 IPR019128:Sister chromatid cohesion protein Dcc1 CG11788 11-Aug-17 DroID_v2017_08 Drer\dscc1 Scer\DCC1 Cele\K09H9.2 Xtro\dscc1 Mmus\Dscc1 Hsap\DSCC1 viable FBgn0028234 l(3)S003405 lethal (3) S003405 http://flybase.org/reports/FBgn0028234 gene - - - l(3)S003405 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022282 l(2)IR24 lethal (2) IR24 http://flybase.org/reports/FBgn0022282 - gene - - - l(2)IR24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011703 RnrL Ribonucleoside diphosphate reductase large subunit http://flybase.org/reports/FBgn0011703 "FBgn0022117, FBgn0026773" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR013509 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ; GO:0004748 | inferred from sequence or structural similarity with UniProtKB:P07742" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000788, InterPro:IPR013346, InterPro:IPR013509 DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR000788, InterPro:IPR013509 activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype deoxyribonucleotide biosynthetic process ; GO:0009263 | inferred from sequence or structural similarity with UniProtKB:P07742 tissue regeneration ; GO:0042246 | inferred from mutant phenotype" - "RntL, CG5371, l(2)k06709, RNR1, DmRNR1, RnrM1, RnrL, RNRL, rnrL" "IPR000788:Ribonucleotide reductase large subunit, C-terminal, IPR005144:ATP-cone domain, IPR008926:Ribonucleotide reductase R1 subunit, N-terminal, IPR013346:Ribonucleotide reductase, class I , alpha subunit, IPR013509:Ribonucleotide reductase large subunit, N-terminal" CG5371 11-Aug-17 DroID_v2017_08 Drer\rrm1 "Scer\RNR3, Scer\RNR1" Cele\rnr-1 Xtro\rrm1 Mmus\Rrm1 Hsap\RRM1 "lethal,recessive,visible,conditional,decreased cell number,increased cell death,viable" "eye disc,conditional,eye,wing,mesothoracic tergum" FBgn0002764 mit(1)14 mitotic 14 http://flybase.org/reports/FBgn0002764 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0070012 BG01257 BG01257 http://flybase.org/reports/FBgn0070012 gene - - - BG01257 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0262679 CG43149 - http://flybase.org/reports/FBgn0262679 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43149 - CG43149 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053432 5SrRNA:CR33432 5SrRNA:CR33432 http://flybase.org/reports/FBgn0053432 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33432, 5SrRNA:CR33432" - CR33432 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265376 CR44317 - http://flybase.org/reports/FBgn0265376 non_protein_coding_gene - - - "CR44317, lincRNA.671" - CR44317 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031505 ND-B14.5B NADH dehydrogenase (ubiquinone) B14.5 B subunit http://flybase.org/reports/FBgn0031505 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR009423 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95298 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95298" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95298 "BcDNA:RE29623, N4BM, ND-B14.5B, CG12400" "IPR009423:NADH:ubiquinone oxidoreductase, subunit b14.5b" CG12400 11-Aug-17 DroID_v2017_08 Drer\ndufc2 - Cele\Y71H2AM.4 - Mmus\Ndufc2 "Hsap\NDUFC2, Hsap\NDUFC2-KCTD14" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum,adult heart,RU486 conditional" FBgn0060574 l(3)S095714b lethal (3) S095714b http://flybase.org/reports/FBgn0060574 gene - - - "0957/14, l(3)S095714b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046119 E(To)6 E(To)6 http://flybase.org/reports/FBgn0046119 gene - - - E(To)6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065824 l(2)SH0362 lethal (2) SH0362 http://flybase.org/reports/FBgn0065824 gene - - - "l(2)SH0362, l(2)SH2 0362" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032259 CG6144 - http://flybase.org/reports/FBgn0032259 protein_coding_gene dioxygenase activity ; GO:0051213 | inferred from biological aspect of ancestor with PANTHER:PTN001405577 ferrous iron binding ; GO:0008198 | inferred from biological aspect of ancestor with PANTHER:PTN001405577 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 - CG6144 "IPR027450:Alpha-ketoglutarate-dependent dioxygenase AlkB-like, IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR032862:Alpha-ketoglutarate-dependent dioxygenase alkB homologue 6" CG6144 11-Aug-17 DroID_v2017_08 "Drer\alkbh6, Drer\med28" - Cele\B0564.2 "Xtro\med28, Xtro\alkbh6" "Mmus\Alkbh6, Mmus\Med28" Hsap\ALKBH6 viable FBgn0029965 Ir7b Ionotropic receptor 7b http://flybase.org/reports/FBgn0029965 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir7b, DmelIR7b, CG15326, IR7b" - CG15326 11-Aug-17 DroID_v2017_08 "Drer\grid1a, Drer\grid1b, Drer\LOC100537813" - "Cele\W02A2.5, Cele\glr-8" - "Mmus\Grid1, Mmus\Grik4" "Hsap\GRIN2C, Hsap\GRID1, Hsap\GRID2" FBgn0032386 CG17745 - http://flybase.org/reports/FBgn0032386 protein_coding_gene - - - CG17745 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000549 Edg43A Ecdysone-dependent gene at 43A http://flybase.org/reports/FBgn0000549 - gene - - - "EDg43, Edg42A, Edg43A" - - 11-Aug-17 DroID_v2017_08 - - - - - - prepupal stage epidermis

FBgn0010177 tu(2)1a tu(2)1a http://flybase.org/reports/FBgn0010177 - gene - - - tu(2)1a - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,partially lethal - majority die" FBgn0002215 l(3)67BDm lethal (3) 67BDm http://flybase.org/reports/FBgn0002215 - gene - - - l(3)67BDm - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0283431 CR46274 - http://flybase.org/reports/FBgn0283431 pseudogene_attribute - - - CR46274 - CR46274 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000968 fs(2)eo3 female sterile (2) eo3 http://flybase.org/reports/FBgn0000968 - gene - - - "fs(2)eoRV64, fs(2)eo-F, fs(2)eo3" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile egg chamber FBgn0025134 su(RpII140[Z36])S13 su(RpII140[Z36])S13 http://flybase.org/reports/FBgn0025134 - gene - - - "Z36[S13], su(RpII140[Z36])S13" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014370 odd-striped odd-striped http://flybase.org/reports/FBgn0014370 - gene - - integral component of membrane ; GO:0016021 | traceable author statement "odd-striped, ost" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052801 CG32801 - http://flybase.org/reports/FBgn0052801 protein_coding_gene - - - "CG14819, CG32801" IPR029214:FAM183 family CG32801 11-Aug-17 DroID_v2017_08 - - - - - - DRSC25614 K 0.087210281 -0.004995594 0.302832784 0.157029665 1.145936083 2.553169582 FBgn0083318 E(smoDN)111 Enhancer of smoDN 111 http://flybase.org/reports/FBgn0083318 gene - - - E(smoDN)111 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029080 iab-8PRE iab-8 Polycomb group response element http://flybase.org/reports/FBgn0029080 regulatory_region - - - "iab-8PRE, iab-8 PRE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035265 PIG-Wb Phosphatidylinositol glycan anchor biosynthesis class W b http://flybase.org/reports/FBgn0035265 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR009447" GPI anchor biosynthetic process ; GO:0006506 | inferred from electronic annotation with InterPro:IPR009447 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009447 "CG18173, PIG-Wb, PIG-W" IPR009447:GWT1 CG18173 11-Aug-17 DroID_v2017_08 Drer\pigw Scer\GWT1 Cele\hpo-20 Xtro\pigw Mmus\Pigw Hsap\PIGW viable DRSC08526 K 0.255558973 -0.299240442 -0.116766381 0.394721301 0.222341615 1.520708487 FBgn0060546 l(3)S098905b lethal (3) S098905b http://flybase.org/reports/FBgn0060546 gene - - - "0989/05, l(3)S098905b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036354 Poc1 Proteome of centrioles 1 http://flybase.org/reports/FBgn0036354 protein_coding_gene - centrosome organization ; GO:0051297 | inferred from mutant phenotype - "Pix, CG10191, Poc1, poc1" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG10191 11-Aug-17 DroID_v2017_08 "Drer\poc1a, Drer\poc1b" Scer\PRP4 "Cele\elpc-2, Cele\npp-23" "Xtro\poc1b, Xtro\poc1a" "Mmus\Poc1a, Mmus\Poc1b" "Hsap\POC1B, Hsap\POC1A" "viable,fertile" "centriole,spermatocyte,centrioleLy)" FBgn0005765 l(1)TK412 lethal (1) TK412 http://flybase.org/reports/FBgn0005765 - gene - - - "l412, l(1)TK412" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0066306 Bexon.s Bexon.s http://flybase.org/reports/FBgn0066306 gene - - - Bexon.s - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083007 snoRNA:Psi28S-1135f snoRNA:Psi28S-1135f http://flybase.org/reports/FBgn0083007 snoRNA_gene - - - "snoRNA:Psi28S-1135f, Psi28S-1135f, psi28S-1135f, CR34599" - CR34599 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028144 l(3)S045902 lethal (3) S045902 http://flybase.org/reports/FBgn0028144 gene - - - "0459/02, l(3)S045902" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0031294 IA-2 IA-2 protein tyrosine phosphatase http://flybase.org/reports/FBgn0031294 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from sequence model protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with SGD:S000002389 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002389 protein dephosphorylation ; GO:0006470 | non-traceable author statement digestive tract development ; GO:0048565 | inferred from mutant phenotype regulation of secretion ; GO:0051046 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "R-PTPX/1A2, CG4355, CG11344, CG31795, anon-WO0153538.69, ia2, IA-2, IA2" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR033522:Receptor-type tyrosine-protein phosphatase-like N/N2, IPR029021:Protein-tyrosine phosphatase-like, IPR021613:Protein-tyrosine phosphatase receptor IA-2 ectodomain, IPR003595:Protein-tyrosine phosphatase, catalytic" CG31795 11-Aug-17 DroID_v2017_08 "Drer\ptprn2, Drer\ptprnb, Drer\ptprna" Scer\PTP1 "Cele\T04F3.3, Cele\ida-1, Cele\ptp-4, Cele\F20H11.4" Xtro\ptprn "Mmus\Ptprn2, Mmus\Ptprn" "Hsap\PTPRN, Hsap\PTPRN2" "partially lethal - majority die,some die during pupal stage,viable" "pupal cuticle,pupal abdomen" FBgn0260378 GSd469 - http://flybase.org/reports/FBgn0260378 gene - - - GSd469 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective" FBgn0002993 olfP olfactory P http://flybase.org/reports/FBgn0002993 - gene - - - olfP - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050281 CG30281 - http://flybase.org/reports/FBgn0050281 protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from sequence or structural similarity with HGNC:3623 chitin binding ; GO:0008061 | inferred from sequence or structural similarity with HGNC:25922 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with HGNC:3623 membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:25922 "CG6676, CG30281, AAM68209, FBpp0071674" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR020837:Fibrinogen, conserved site, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG30281 11-Aug-17 DroID_v2017_08 "Drer\si:zfos-2330d3.8, Drer\si:zfos-2330d3.3, Drer\zgc:171687, Drer\LOC100007488, Drer\si:zfos-2330d3.1, Drer\si:ch211-287a12.9, Drer\angptl2a, Drer\si:dkeyp-51b7.3, Drer\fgg, Drer\angptl4, Drer\zmp:0000000846, Drer\LOC555374, Drer\fgl2b, Drer\tnw, Drer\si:ch1073-110a20.3, Drer\tnc, Drer\fga, Drer\angptl2b, Drer\angptl3, Drer\mfap4, Drer\fgb, Drer\si:zfos-2330d3.6, Drer\angpt4, Drer\tnr, Drer\angpt2a, Drer\fgl2a, Drer\si:ch211-157b11.8, Drer\si:ch1073-110a20.2, Drer\wu:fj11g02, Drer\angpt1, Drer\zgc:173915, Drer\fgl1, Drer\angptl1a, Drer\angpt2b, Drer\tnxba, Drer\si:ch211-203k16.3, Drer\angptl6, Drer\fibcd1, Drer\angptl5, Drer\si:ch1073-110a20.1, Drer\zgc:194887, Drer\angptl7" - "Cele\ensh-1, Cele\K10D3.4, Cele\W05B2.2, Cele\T15B7.1, Cele\C08G9.2, Cele\Y43C5A.2, Cele\Y69H2.3, Cele\Y26D4A.12, Cele\Y69H2.10, Cele\eea-1, Cele\ZC504.1" "Xtro\angptl4, Xtro\tnn, Xtro\tnc, Xtro\angpt4, Xtro\fibcd1, Xtro\fgb, Xtro\fgl2, Xtro\tnr, Xtro\LOC100488177, Xtro\fga, Xtro\LOC100497330, Xtro\fcn3, Xtro\fcn1, Xtro\angptl3, Xtro\fgg, Xtro\angptl2, Xtro\angpt1, Xtro\fgl1, Xtro\fcn2, Xtro\LOC100491105, Xtro\angptl5, Xtro\mfap4, Xtro\tnxb" "Mmus\Angptl3, Mmus\Fgl1, Mmus\Angpt4, Mmus\Tnxb, Mmus\Mfap4, Mmus\Tnc, Mmus\Tnr, Mmus\Fibcd1, Mmus\Angptl1, Mmus\Angptl2, Mmus\Angpt2, Mmus\Fga, Mmus\Angpt1, Mmus\Fcna, Mmus\Fgg, Mmus\Angptl4, Mmus\Fgb, Mmus\Angptl6, Mmus\Angptl7, Mmus\Fgl2, Mmus\Tnn, Mmus\Fcnb" "Hsap\TNXB, Hsap\FCN1, Hsap\ANGPTL3, Hsap\ANGPTL5, Hsap\ANGPT2, Hsap\TNR, Hsap\ANGPTL7, Hsap\ANGPT4, Hsap\TNC, Hsap\ANGPTL6, Hsap\ANGPT1, Hsap\MFAP4, Hsap\FCN2, Hsap\FGL2, Hsap\TNN, Hsap\FIBCD1, Hsap\FGL1, Hsap\ANGPTL1, Hsap\FGG, Hsap\ANGPTL4, Hsap\FGB, Hsap\FCN3, Hsap\FGA, Hsap\ANGPTL2" FBgn0025644 CG14424 - http://flybase.org/reports/FBgn0025644 - protein_coding_gene - - - "EG:100G7.5, CG14424" - CG14424 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0038415 CG17929 - http://flybase.org/reports/FBgn0038415 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 CG17929 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG17929 11-Aug-17 DroID_v2017_08 "Drer\slc2a10, Drer\slc2a12, Drer\slc2a8, Drer\LOC101882338, Drer\slc2a13b, Drer\slc2a6" "Scer\HXT2, Scer\MPH2, Scer\VBA3, Scer\RGT2, Scer\MAL31, Scer\MAL11, Scer\HXT4, Scer\GEX1, Scer\HXT11, Scer\HXT3, Scer\VBA4, Scer\AZR1, Scer\HXT10, Scer\YDL199C, Scer\HXT1, Scer\HXT9, Scer\HXT13, Scer\HXT15, Scer\GAL2, Scer\HXT8, Scer\HXT14, Scer\HXT17, Scer\ENB1, Scer\YMR279C, Scer\VBA5, Scer\MPH3, Scer\GEX2, Scer\SNF3, Scer\HXT7, Scer\ITR1, Scer\HXT6, Scer\VBA2, Scer\HXT16, Scer\HXT5, Scer\STL1, Scer\YFL040W, Scer\ITR2, Scer\SGE1, Scer\ATR1, Scer\VBA1, Scer\YDR387C" "Cele\fgt-1, Cele\hmit-1.2" "Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a12, Xtro\slc2a6" "Mmus\Slc2a13, Mmus\Slc2a12, Mmus\Slc2a6, Mmus\Slc2a10, Mmus\Slc2a8" "Hsap\SLC2A10, Hsap\SLC2A12, Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SLC2A8" viable FBgn0002449 l(3)SG2 lethal (3) SG2 http://flybase.org/reports/FBgn0002449 - gene - - - "l(3)13m-237, l(3)SG2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0033691 CG8860 - http://flybase.org/reports/FBgn0033691 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from electronic annotation with InterPro:IPR008158 protein targeting ; GO:0006605 | inferred from electronic annotation with InterPro:IPR001901 neurogenesis ; GO:0022008 | inferred from mutant phenotype "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001901, InterPro:IPR008158" "BcDNA:GM14157, CG8860" "IPR001901:Protein translocase complex, SecE/Sec61-gamma subunit, IPR008158:Protein translocase SEC61 complex, gamma subunit, IPR023391:Protein translocase SecE domain, IPR022943:Preprotein translocase subunit SecE" CG8860 11-Aug-17 DroID_v2017_08 Drer\sec61g "Scer\CHL4, Scer\SSS1" Cele\emo-1 Xtro\sec61g "Mmus\Sec61g, Mmus\Gm12881, Mmus\LOC102637269, Mmus\Gm4184" Hsap\SEC61G "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0004189 snRNA:U6:96Ab small nuclear RNA U6 at 96Ab http://flybase.org/reports/FBgn0004189 "FBgn0003455, FBgn0003939, FBgn0003940" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U6 snRNP ; GO:0005688 | inferred from sequence or structural similarity "CR32867, snRNA:U6:96Ab, U6, U6-2, U6-96Ab, snRNA-b, U6 RNA, U6snRNA, DU6-2, snRNA[[4]], K1, dU6, snRNA:U6, snRNA6, snRNA4, U6snRNA96Ab, U6:96Ab, U6 snRNA, U6-snRNA" - CR32867 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053965 CG33965 - http://flybase.org/reports/FBgn0053965 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "CG1211, CG33965" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR000595:Cyclic nucleotide-binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG33965 11-Aug-17 DroID_v2017_08 "Drer\rlbp1a, Drer\ttpa, Drer\rlbp1b, Drer\sec14l8, Drer\clvs2, Drer\ttpal, Drer\sec14l7" "Scer\SEC14, Scer\SFH5, Scer\YKL091C" - "Xtro\sec14l1, Xtro\clvs2, Xtro\rlbp1, Xtro\ttpal, Xtro\mospd2, Xtro\sec14l3, Xtro\clvs1, Xtro\sec14l5, Xtro\ttpa" "Mmus\Ttpal, Mmus\Rlbp1, Mmus\Sec14l1, Mmus\Sec14l4, Mmus\Sec14l2, Mmus\Clvs2, Mmus\Sec14l5, Mmus\Sec14l3, Mmus\Clvs1, Mmus\Ttpa" "Hsap\SEC14L2, Hsap\SEC14L6, Hsap\SEC14L4, Hsap\CLVS1, Hsap\TTPAL, Hsap\TTPA, Hsap\SEC14L5, Hsap\SEC14L3, Hsap\SEC14L1, Hsap\CLVS2, Hsap\RLBP1" FBgn0035741 BBS1 Bardet-Biedl syndrome 1 http://flybase.org/reports/FBgn0035741 protein_coding_gene patched binding ; GO:0005113 | inferred from biological aspect of ancestor with PANTHER:PTN000466746 smoothened binding ; GO:0005119 | inferred from biological aspect of ancestor with PANTHER:PTN000466746 non-motile cilium assembly ; GO:1905515 | inferred from electronic annotation with InterPro:IPR028784 cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:966 cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern protein localization to cilium ; GO:0061512 | inferred from biological aspect of ancestor with PANTHER:PTN000466746 BBSome ; GO:0034464 | inferred from sequence or structural similarity with HGNC:966 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN000466746 cilium ; GO:0005929 | inferred by curator from GO:0060271 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000466746 BBSome ; GO:0034464 | inferred from biological aspect of ancestor with PANTHER:PTN000466746 axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000466746 "CG14825, BBS1" "IPR032728:Bardet-Biedl syndrome 1, N-terminal, IPR015943:WD40/YVTN repeat-like-containing domain, IPR028784:Bardet-Biedl syndrome 1 protein" CG14825 11-Aug-17 DroID_v2017_08 Drer\bbs1 - Cele\bbs-1 Xtro\bbs1 Mmus\Bbs1 "Hsap\BBS1, Hsap\DPP3" viable FBgn0032929 Mcm10 Minichromosome maintenance 10 http://flybase.org/reports/FBgn0032929 protein_coding_gene single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000335708 DNA replication origin binding ; GO:0003688 | inferred from biological aspect of ancestor with PANTHER:PTN000335708 heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype negative regulation of compound eye retinal cell apoptotic process ; GO:1901693 | inferred from mutant phenotype positive regulation of R7 cell differentiation ; GO:0045678 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype positive regulation of mitotic cell cycle ; GO:0045931 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from biological aspect of ancestor with PANTHER:PTN000335708 replication fork protection complex ; GO:0031298 | inferred from biological aspect of ancestor with PANTHER:PTN000335708 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q7L590 nucleus ; GO:0005634 | inferred from direct assay "CG9241, DmMCM10, Scim19, Mcm10, mcm10, dMcm10" "IPR015408:Zinc finger, Mcm10/DnaG-type, IPR015411:Replication factor Mcm10, C-terminal" CG9241 11-Aug-17 DroID_v2017_08 Drer\mcm10 Scer\MCM10 Cele\mcm-10 Xtro\mcm10 Mmus\Mcm10 Hsap\MCM10 "viable,partially lethal - majority die,recessive,mitotic cell cycle defective,suppressor of variegation,dominant,small body,increased cell death,lethal - all die during pupal stage" "condensed nuclear chromosome,embryonic/larval brain,nurse cell,polytene chromosome,nuclear chromosome,eye,ommatidium,eye disc,photoreceptor cell R7 | third instar larval stage,photoreceptor cell R7" FBgn0058088 CG40088 - http://flybase.org/reports/FBgn0058088 protein_coding_gene - - - CG40088 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025334 PHDP Putative homeodomain protein http://flybase.org/reports/FBgn0025334 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "anon-60Ac, CG11182, PHDP" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG11182 11-Aug-17 DroID_v2017_08 "Drer\prop1, Drer\drgx, Drer\phox2ba, Drer\mxtx2, Drer\phox2bb, Drer\mxtx1, Drer\mixl1, Drer\phox2a, Drer\dharma" - "Cele\ceh-17, Cele\ceh-51" "Xtro\drgx, Xtro\phox2b, Xtro\nkx6-3, Xtro\nkx6-2, Xtro\phox2a" "Mmus\Mixl1, Mmus\Phox2a, Mmus\Prrxl1, Mmus\Phox2b, Mmus\Emx1, Mmus\Emx2" "Hsap\PHOX2A, Hsap\DRGX, Hsap\MIXL1, Hsap\PHOX2B" viable FBgn0060999 l(3)S027005 lethal (3) S027005 http://flybase.org/reports/FBgn0060999 gene - - - "0270/05, l(3)S027005" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0004526 l(4)102CDi lethal (4) 102CDi http://flybase.org/reports/FBgn0004526 - gene - - - "l(4)CDi, l(4)ST-2, l(4)14, l(4)26, l(4)102CDi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" FBgn0031715 tomb tombola http://flybase.org/reports/FBgn0031715 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with aly inferred from physical interaction with comr positive regulation of transcription involved in meiotic cell cycle ; GO:0051039 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype nuclear chromatin ; GO:0000790 | inferred from direct assay "CG14016, tomb, Tomb" "IPR005172:CRC domain, IPR028307:Lin-54 family, IPR033467:Tesmin/TSO1-like CXC domain" CG14016 11-Aug-17 DroID_v2017_08 "Drer\lin54, Drer\mtl5" - Cele\lin-54 Xtro\lin54 "Mmus\Lin54, Mmus\Mtl5" "Hsap\TESMIN, Hsap\LIN54" "viable,male sterile,meiotic cell cycle defective,male,female fertile" "testis,nuclear chromosome & primary spermatocyte" FBgn0031772 CG13994 - http://flybase.org/reports/FBgn0031772 protein_coding_gene protein serine/threonine phosphatase inhibitor activity ; GO:0004865 | inferred from biological aspect of ancestor with PANTHER:PTN000464544 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype negative regulation of phosphoprotein phosphatase activity ; GO:0032515 | inferred from biological aspect of ancestor with PANTHER:PTN000464544 protein phosphatase type 1 complex ; GO:0000164 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000464544 "BcDNA:AT31406, CG13994" IPR011107:Protein phosphatase inhibitor CG13994 11-Aug-17 DroID_v2017_08 Drer\ppp1r11 Scer\YPI1 "Cele\ZK945.8, Cele\C07H6.2, Cele\K10H10.7" Xtro\ppp1r11 Mmus\Ppp1r11 Hsap\PPP1R11 "lethal,lethal - all die before end of pupal stage,some die during pupal stage,viable" embryonic/larval brain FBgn0020841 l(2)BV238 "Blacksburg, VA 238" http://flybase.org/reports/FBgn0020841 - gene - - - l(2)BV238 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005095 fs(2)OWc7 female sterile (2) OWc7 http://flybase.org/reports/FBgn0005095 - gene - - - fs(2)OWc7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038244 CG7987 - http://flybase.org/reports/FBgn0038244 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "anon-WO0118547.245, CG7987" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7987 11-Aug-17 DroID_v2017_08 "Drer\znf516, Drer\LOC108181161, Drer\znf983, Drer\znf536" - "Cele\Y55F3AM.14, Cele\hinf-1, Cele\C27A12.2" - "Mmus\Zfp219, Mmus\Wiz, Mmus\Zfp217, Mmus\Zfp536" "Hsap\ZNF624, Hsap\ZNF761, Hsap\ZNF536, Hsap\ZNF814, Hsap\WIZ, Hsap\ZNF219" viable FBgn0003411 sisA sisterless A http://flybase.org/reports/FBgn0003411 - protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with gt protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Bap60 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement" "sex determination, establishment of X:A ratio ; GO:0007540 | non-traceable author statement sex determination, establishment of X:A ratio ; GO:0007540 | traceable author statement posterior midgut development ; GO:0007497 | inferred from mutant phenotype sex determination ; GO:0007530 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype endoderm development ; GO:0007492 | inferred from mutant phenotype sex determination ; GO:0007530 | inferred from genetic interaction with Sxl primary sex determination ; GO:0007538 | inferred from mutant phenotype anterior midgut development ; GO:0007496 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0045944 "sis-a, sis-A, sis a, sis A, sisa, CG1641, sisA, DM29" - CG1641 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , embryonic stage | cycle 8-14 " " yolk nucleus

, cleavage nucleus

" "lethal,male,recessive,heat sensitive,female,partially,wild-type,viable,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval midgut,anterior,posterior embryonic/larval midgut,yolk,yolk granule" FBgn0084949 S50.3 S50.3 http://flybase.org/reports/FBgn0084949 gene - - - S50.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,fertile" eye FBgn0038960 CG13855 - http://flybase.org/reports/FBgn0038960 protein_coding_gene - - - CG13855 - CG13855 11-Aug-17 DroID_v2017_08 Drer\iqub - "Cele\fbxa-53, Cele\fbxa-51, Cele\Y52B11A.12, Cele\B0294.3" Xtro\iqub Mmus\Iqub Hsap\IQUB viable FBgn0004530 l(4)102CDl lethal (4) 102CDl http://flybase.org/reports/FBgn0004530 - gene - - - "l(4)AM-1, l(4)22, l(4)102CDl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0061002 l(3)S026543b lethal (3) S026543b http://flybase.org/reports/FBgn0061002 gene - - - "0265/43, l(3)S026543b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031560 CG16713 - http://flybase.org/reports/FBgn0031560 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CT37195, CG16713" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG16713 11-Aug-17 DroID_v2017_08 "Drer\spint1b, Drer\wfikkn2b, Drer\tfpi2, Drer\tfpia, Drer\spint2, Drer\si:dkey-117n7.5, Drer\si:dkeyp-73b11.8, Drer\col6a4a, Drer\wfikkn1, Drer\spint1a, Drer\wfikkn2a, Drer\ambp" - "Cele\K10D3.4, Cele\R12A1.3, Cele\T22F7.3, Cele\T22F7.5, Cele\mlt-11" "Xtro\spint1, Xtro\spint2, Xtro\ambp, Xtro\tfpi2" "Mmus\Spint2, Mmus\Wfikkn2, Mmus\Wfdc6a, Mmus\Wfdc6b, Mmus\Wfdc8, Mmus\Spint1, Mmus\Eppin, Mmus\Spint4, Mmus\Tfpi2, Mmus\Wfikkn1, Mmus\Ambp, Mmus\Spint5, Mmus\Tfpi, Mmus\Spint3" "Hsap\WFDC6, Hsap\WFIKKN2, Hsap\SPINT3, Hsap\SPINT2, Hsap\TFPI, Hsap\TFPI2, Hsap\AMBP, Hsap\SPINT4, Hsap\SPINT1, Hsap\WFIKKN1, Hsap\WFDC8, Hsap\EPPIN-WFDC6" "viable,visible" "chaeta,supernumerary" FBgn0031950 Herp Homocysteine-induced endoplasmic reticulum protein http://flybase.org/reports/FBgn0031950 protein_coding_gene - endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from genetic interaction with ninaE microtubule associated complex ; GO:0005875 | inferred from direct assay "Herp, dHerp, CG14536, CG1453, herp" "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG14536 11-Aug-17 DroID_v2017_08 "Drer\herpud1, Drer\herpud2" - Cele\tag-353 "Xtro\herpud1, Xtro\herpud2" "Mmus\Herpud2, Mmus\Herpud1" "Hsap\HERPUD2, Hsap\HERPUD1" "viable,fertile" FBgn0260332 GSd204 - http://flybase.org/reports/FBgn0260332 gene - - - GSd204 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0033076 CG15233 - http://flybase.org/reports/FBgn0033076 protein_coding_gene - - - "BEST:LD11861, CG15233" - CG15233 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060483 l(3)S110812 lethal (3) S110812 http://flybase.org/reports/FBgn0060483 gene - - - "1108/12, l(3)S110812" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0050159 CG30159 - http://flybase.org/reports/FBgn0050159 protein_coding_gene - regulation of MAPK cascade ; GO:0043408 | inferred from biological aspect of ancestor with PANTHER:PTN002002446 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN002002446 "CG3364, CG30159" - CG30159 11-Aug-17 DroID_v2017_08 Drer\c18h3orf33 - "Cele\F32A11.1, Cele\W09H1.3" - Mmus\E130311K13Rik Hsap\C3orf33 viable FBgn0026412 Leucine-aminopeptidase Leucine aminopeptidase http://flybase.org/reports/FBgn0026412 - gene - - - Leucine-aminopeptidase - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083151 S(smoDN)204 Suppressor of smoDN 204 http://flybase.org/reports/FBgn0083151 gene - - - S(smoDN)204 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261927 CR42794 - http://flybase.org/reports/FBgn0261927 non_protein_coding_gene - - - "CG42794, CR42794" - CR42794 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032116 Mco1 Multicopper oxidase-1 http://flybase.org/reports/FBgn0032116 protein_coding_gene "copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR002355, InterPro:IPR011706, InterPro:IPR011707 ferroxidase activity ; GO:0004322 | inferred from direct assay iron ion transmembrane transporter activity ; GO:0005381 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001709969" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001117, InterPro:IPR011706 iron ion homeostasis ; GO:0055072 | inferred from mutant phenotype iron ion transport ; GO:0006826 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 iron assimilation by reduction and transport ; GO:0033215 | inferred from biological aspect of ancestor with PANTHER:PTN001709969" high-affinity iron permease complex ; GO:0033573 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 basal part of cell ; GO:0045178 | inferred from direct assay intrinsic component of external side of plasma membrane ; GO:0031233 | inferred from sequence model cell surface ; GO:0009986 | inferred from direct assay "Mco1, MCO1, CG3759" "IPR001117:Multicopper oxidase, type 1, IPR002355:Multicopper oxidase, copper-binding site, IPR008972:Cupredoxin, IPR011706:Multicopper oxidase, type 2, IPR011707:Multicopper oxidase, type 3, IPR033138:Multicopper oxidases, conserved site" CG3759 11-Aug-17 DroID_v2017_08 "Drer\cp, Drer\hephl1b" "Scer\GMC1, Scer\FET3, Scer\FET5" Cele\F21D5.3 Xtro\hephl1 "Mmus\Cp, Mmus\Heph, Mmus\Hephl1" "Hsap\HEPHL1, Hsap\HEPH, Hsap\MUC2, Hsap\CP" "viable,chemical resistant,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC02720 K 0.273267251 0.381731379 -0.434762187 -0.004356263 1.38288874 1.757601482 FBgn0000614 Ext Extras http://flybase.org/reports/FBgn0000614 - gene - - - Ext - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" wing vein FBgn0035146 CG13893 - http://flybase.org/reports/FBgn0035146 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 "transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071, InterPro:IPR009038" intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 CG13893 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR009038:GOLD domain, IPR011074:CRAL/TRIO, N-terminal domain" CG13893 11-Aug-17 DroID_v2017_08 "Drer\sec14l7, Drer\clvs2, Drer\fyco1b, Drer\ttpal, Drer\ttpa, Drer\rlbp1a, Drer\sec14l8" "Scer\YKL091C, Scer\SEC14, Scer\SFH5" "Cele\F18A11.2, Cele\T03F7.7, Cele\C11H1.9, Cele\H41C03.1, Cele\C11H1.5, Cele\C34C12.6, Cele\R03A10.5, Cele\T23G5.2, Cele\cgr-1, Cele\ctg-1, Cele\F28H7.8, Cele\ctg-2, Cele\F20G2.3" "Xtro\rlbp1, Xtro\sec14l5, Xtro\clvs1, Xtro\clvs2, Xtro\ttpa, Xtro\mospd2, Xtro\sec14l1, Xtro\ttpal, Xtro\sec14l3" "Mmus\Clvs2, Mmus\Sec14l5, Mmus\Sec14l4, Mmus\Sec14l1, Mmus\Clvs1, Mmus\Sec14l3, Mmus\Ttpa, Mmus\Ttpal, Mmus\Rlbp1, Mmus\Sec14l2" "Hsap\SEC14L1, Hsap\SEC14L4, Hsap\SEC14L5, Hsap\MTFP1, Hsap\SEC14L3, Hsap\RLBP1, Hsap\TTPA, Hsap\SEC14L6, Hsap\TTPAL, Hsap\CLVS2, Hsap\SEC14L2, Hsap\CLVS1" "viable,fertile" FBgn0085246 CG34217 - http://flybase.org/reports/FBgn0085246 protein_coding_gene - - - CG34217 - CG34217 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001352 l(1)1EFa lethal (1) 1EFa http://flybase.org/reports/FBgn0001352 - gene - - - "l(1)BA1, l(1)1EFa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036105 Blos4 "Biogenesis of lysosome-related organelles complex 1, subunit 4" http://flybase.org/reports/FBgn0036105 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Dysb eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype intracellular transport ; GO:0046907 | inferred from biological aspect of ancestor with PANTHER:PTN001443055 BLOC-1 complex ; GO:0031083 | inferred from biological aspect of ancestor with PANTHER:PTN001443055 BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:24206 "CG14149, Dm Blos4, NP_648414, Blos4, blos4" IPR024857:Cappuccino CG14149 11-Aug-17 DroID_v2017_08 Drer\bloc1s4 - - Xtro\bloc1s4 Mmus\Bloc1s4 "Hsap\BLOC1S4, Hsap\BCAS4" "eye color defective,viable" FBgn0011330 l(3)j2C3 lethal (3) j2C3 http://flybase.org/reports/FBgn0011330 - gene - - - l(3)j2C3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265303 CR44276 - http://flybase.org/reports/FBgn0265303 non_protein_coding_gene - - - CR44276 - CR44276 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035323 CG13807 - http://flybase.org/reports/FBgn0035323 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR028271 methylation ; GO:0032259 | inferred from electronic annotation with InterPro:IPR028271 lateral inhibition ; GO:0046331 | inferred from mutant phenotype mRNA cap binding complex ; GO:0005845 | inferred from electronic annotation with InterPro:IPR028271 CG13807 IPR028271:RNMT-activating mini protein CG13807 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Fam103a1, Mmus\Gm10767" Hsap\FAM103A1 "viable,fertile,visible" "chaeta,trichogen cell" FBgn0003011 ort ora transientless http://flybase.org/reports/FBgn0003011 "FBgn0016658, FBgn0038726" protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 histamine-gated chloride channel activity ; GO:0019182 | inferred from direct assay histamine-gated chloride channel activity ; GO:0019182 | inferred from sequence or structural similarity chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype chloride transport ; GO:0006821 | inferred from direct assay adult behavior ; GO:0030534 | inferred from mutant phenotype response to toxic substance ; GO:0009636 | inferred from mutant phenotype thermotaxis ; GO:0043052 | inferred from mutant phenotype response to ether ; GO:0045472 | inferred from mutant phenotype histamine-gated chloride channel complex ; GO:0019183 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG7411, hclA, HisCl2, hisCl2, DmHisCl2, Hist1, GluCI, ora, ort, HisCl, HisC12, Ort, DMHisClalpha1, Dm-hclA, ORT, HisCI2, HA-CI I, CT22815, HclA, HisCl-alpha1" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG7411 11-Aug-17 DroID_v2017_08 "Drer\LOC100001259, Drer\gabrb3, Drer\LOC562831, Drer\gabrb4, Drer\si:dkey-52k1.6, Drer\glrbb, Drer\gabra5, Drer\gabrp, Drer\gabrb2, Drer\gabrr1, Drer\gabrr2b, Drer\gabra6a, Drer\glra4a, Drer\zgc:110204, Drer\si:dkey-155h10.3, Drer\gabrr3a, Drer\gabra6b, Drer\gabrb1, Drer\gabrg2, Drer\glrba, Drer\glra3, Drer\gabrr2a, Drer\gabrd, Drer\glra2, Drer\gabra1, Drer\LOC100330554, Drer\glra1, Drer\glra4b" - "Cele\glc-4, Cele\lgc-45, Cele\lgc-43, Cele\lgc-37, Cele\lgc-41, Cele\lgc-42, Cele\gab-1, Cele\lgc-36, Cele\glc-2, Cele\lgc-44, Cele\ggr-1, Cele\unc-49, Cele\lgc-38, Cele\avr-14, Cele\glc-3, Cele\avr-15, Cele\lgc-39, Cele\lgc-40" "Xtro\gabra2, Xtro\gabra6, Xtro\gabrg2, Xtro\gabra5, Xtro\gabrp, Xtro\glra1, Xtro\glra2, Xtro\gabrb3, Xtro\glra3, Xtro\LOC100490720, Xtro\gabrr3, Xtro\gabrd, Xtro\glrb" "Mmus\Gabrg1, Mmus\Glra2, Mmus\Glra4, Mmus\Gabrd, Mmus\Gabrg3, Mmus\Gabrb1, Mmus\Gabrq, Mmus\Gabrr2, Mmus\Glra1, Mmus\Gabrr1, Mmus\Gabra3, Mmus\Gabrb2, Mmus\Gabra5, Mmus\Gabrr3, Mmus\Glrb, Mmus\Gabra1, Mmus\Gabrg2, Mmus\Gabra2, Mmus\Glra3, Mmus\Gabra6, Mmus\Gabrb3, Mmus\Gabre, Mmus\Gabrp" "Hsap\GABRA5, Hsap\GABRR3, Hsap\GLRA3, Hsap\GABRD, Hsap\GABRA1, Hsap\GABRQ, Hsap\GABRA6, Hsap\GABRG2, Hsap\GABRB3, Hsap\GABRE, Hsap\GABRA2, Hsap\GABRB1, Hsap\GABRG3, Hsap\GABRP, Hsap\GABRG1, Hsap\GLRA4, Hsap\GLRB, Hsap\GABRB2, Hsap\GLRA2, Hsap\GABRR1, Hsap\GLRA1, Hsap\GABRA4, Hsap\GABRR2" adult stage " head

, lamina && medulla && lobula && brain | medial && photoreceptor

" "viable,fertile,neurophysiology defective,chemical sensitive,phototaxis defective,optomotor response defective,thermotaxis behavior defective,recessive,poor,conditional,reduced,chemical resistant,visual behavior defective,behavior defective,paralytic,heat sensitive" "rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell" FBgn0033155 Br140 "Bromodomain-containing protein, 140kD" http://flybase.org/reports/FBgn0033155 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 histone acetyltransferase activity (H3-K23 specific) ; GO:0043994 | inferred from direct assay dorsal/ventral axon guidance ; GO:0033563 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay MOZ/MORF histone acetyltransferase complex ; GO:0070776 | inferred from direct assay "CG1845, Br140" "IPR000313:PWWP domain, IPR001487:Bromodomain, IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019542:Enhancer of polycomb-like, N-terminal, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR034732:Extended PHD (ePHD) domain, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1845 11-Aug-17 DroID_v2017_08 "Drer\brpf1, Drer\brd1a, Drer\jade1, Drer\jade3, Drer\brpf3b, Drer\brpf3a, Drer\mllt10, Drer\brd1b" "Scer\NTO1, Scer\SNT2" "Cele\phf-15, Cele\lin-49, Cele\zfp-1" "Xtro\brpf1, Xtro\brd1, Xtro\jade3, Xtro\jade1, Xtro\brpf3" "Mmus\Jade3, Mmus\Jade1, Mmus\Mllt10, Mmus\Brpf1, Mmus\Brd1, Mmus\Mllt6, Mmus\Brpf3" "Hsap\BRD1, Hsap\MLLT10, Hsap\JADE1, Hsap\MLLT6, Hsap\BRPF3, Hsap\BRPF1, Hsap\JADE3" "neuroanatomy defective,somatic clone,viable,fertile,visible" "axon | somatic clone | third instar larval stage,mesothoracic tergum" FBgn0034882 Eglp1 Entomoglyceroporin 1 http://flybase.org/reports/FBgn0034882 protein_coding_gene channel activity ; GO:0015267 | inferred from sequence or structural similarity with Drip water channel activity ; GO:0015250 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 ion transmembrane transport ; GO:0034220 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 transmembrane transport ; GO:0055085 | inferred from sequence or structural similarity with Drip integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Drip integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 "anon-WO0140519.151, CG5398, Aqp5398, Eglp1, Eglp 1" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR023271:Aquaporin-like" CG5398 11-Aug-17 DroID_v2017_08 "Drer\aqp8b, Drer\mipa, Drer\aqp8a.2, Drer\aqp8a.1, Drer\aqp1a.2, Drer\aqp4, Drer\aqp10a, Drer\mipb, Drer\aqp1a.1" "Scer\AQY1, Scer\YLL053C, Scer\AQY2" "Cele\aqp-6, Cele\aqp-4, Cele\aqp-5" "Xtro\aqp2, Xtro\aqp5, Xtro\mip, Xtro\LOC100216133" "Mmus\Aqp4, Mmus\Aqp5, Mmus\Aqp8, Mmus\Aqp6, Mmus\Mip, Mmus\Aqp1, Mmus\Aqp2" "Hsap\AQP1, Hsap\MIP, Hsap\AQP10, Hsap\AQP4, Hsap\AQP6, Hsap\AQP2, Hsap\AQP5, Hsap\AQP8" viable FBgn0037921 CG6808 - http://flybase.org/reports/FBgn0037921 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG31372, CG6808" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6808 11-Aug-17 DroID_v2017_08 - Scer\ZAP1 - - "Mmus\Zfp445, Mmus\Zfp24, Mmus\Zfp369, Mmus\Zfp110, Mmus\Zscan5b, Mmus\Zfp691" Hsap\ZNF691 viable DRSC14934 I -0.236061377 1.744418692 0.074367332 0.163766252 0.226339758 0.765332869 FBgn0263339 CR43420 - http://flybase.org/reports/FBgn0263339 non_protein_coding_gene - - - CR43420 - CR43420 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065093 snmRNA:430 small non-messenger RNA 430 http://flybase.org/reports/FBgn0065093 non_protein_coding_gene - - - "Dm-430, snmRNA:430" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262367 mir-13b-1 mir-13b-1 stem loop http://flybase.org/reports/FBgn0262367 miRNA_gene - - - "miR-13b-1, mir-13b, 13b-1, mir-13b-1, dme-mir-13b-1, Dme-miR-13b, 13b-1/2, CR42878, miR-13b, miR-13, mir-13, CR32933, miR-13B, dme-mir-13b, miRNA-13b-1, miRNA-13b, dme-miR-13b, dme-miR-13b-3p" - CR42878 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage viable FBgn0038418 pad poils au dos http://flybase.org/reports/FBgn0038418 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG10309, pad" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10309 11-Aug-17 DroID_v2017_08 "Drer\egr1, Drer\klf13, Drer\egr2a, Drer\zic2b, Drer\si:rp71-1g18.1, Drer\znf438, Drer\sp2, Drer\sp4, Drer\egr3, Drer\egr2b, Drer\sp3b, Drer\klf5l, Drer\zgc:171901" "Scer\AZF1, Scer\ZAP1" - "Xtro\egr2, Xtro\sp3, Xtro\egr1, Xtro\klf9, Xtro\znf438" "Mmus\Sp4, Mmus\Klf6, Mmus\Gfi1b, Mmus\Egr2, Mmus\Zfp438, Mmus\Klf5, Mmus\Zscan21, Mmus\Egr1, Mmus\Egr3" "Hsap\ZFP42, Hsap\ZNF79, Hsap\ZNF69, Hsap\EGR3, Hsap\SP4, Hsap\ZKSCAN2, Hsap\EGR1, Hsap\ZNF438, Hsap\ZNF595, Hsap\EGR2, Hsap\GFI1B, Hsap\GLI4" "lethal - all die before end of pupal stage,some die during pupal stage,viable,recessive,fertile" "mesothoracic tergum & macrochaeta | ectopic,microchaeta,leg,mesothoracic tergum & macrochaeta | ectopicsbd26),mesothoracic tergum & macrochaeta | ectopicP115),anterior scutellar bristle,female,supernumerary,posterior postalar bristle,posterior supraalar bristle,presutural bristle,mesothoracic tergum & microchaeta,sensillum campaniformium & wing | supernumerary" FBgn0032334 CG14914 - http://flybase.org/reports/FBgn0032334 protein_coding_gene - - - CG14914 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053552 CG33552 - http://flybase.org/reports/FBgn0053552 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:25539 zinc ion binding ; GO:0008270 | inferred from sequence model protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:25539 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:25539 CG33552 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG33552 11-Aug-17 DroID_v2017_08 Drer\rfwd3 - "Cele\T01G5.7, Cele\Y4C6A.3, Cele\F19G12.1" - Mmus\Rfwd3 Hsap\RFWD3 viable FBgn0035360 CG1246 - http://flybase.org/reports/FBgn0035360 protein_coding_gene - - - CG1246 - CG1246 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266845 CG45307 - http://flybase.org/reports/FBgn0266845 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45307, lincRNA.77" - CG45307 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011585 dame daughterless maternal enhancer http://flybase.org/reports/FBgn0011585 - gene - - - "E(2)AX, dame" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033705 CG13168 - http://flybase.org/reports/FBgn0033705 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13168 - CG13168 11-Aug-17 DroID_v2017_08 Drer\iqcd - - Xtro\iqcd Mmus\Iqcd Hsap\IQCD "partially lethal - majority die,some die during pupal stage" FBgn0259757 ms(2)Fra-39 - http://flybase.org/reports/FBgn0259757 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - ms(2)Fra-39 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "Y chromosome loop,spermatozoon" FBgn0265317 CG44290 - http://flybase.org/reports/FBgn0265317 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44290, lincRNA.869" - CG44290 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266413 CR45053 - http://flybase.org/reports/FBgn0266413 non_protein_coding_gene - - - CR45053 - CR45053 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060785 l(3)S059706a lethal (3) S059706a http://flybase.org/reports/FBgn0060785 gene - - - "0597/06, l(3)S059706a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027558 pgant3 polypeptide GalNAc transferase 3 http://flybase.org/reports/FBgn0027558 FBgn0062232 protein_coding_gene "polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay acetylgalactosaminyltransferase activity ; GO:0008376 | inferred from direct assay transferase activity, transferring glycosyl groups ; GO:0016757 | inferred from direct assay" extracellular matrix constituent secretion ; GO:0070278 | inferred from mutant phenotype cell-substrate adhesion ; GO:0031589 | inferred from mutant phenotype protein O-linked glycosylation ; GO:0006493 | inferred from direct assay inferred from mutant phenotype O-glycan processing ; GO:0016266 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay regulation of cell adhesion mediated by integrin ; GO:0033628 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement "CG4445, BcDNA:GH09147, anon-WO0118547.119, pgant3" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG4445 11-Aug-17 DroID_v2017_08 "Drer\galnt12, Drer\galnt2, Drer\galnt14, Drer\LOC568645, Drer\galnt8a.1, Drer\wbscr17, Drer\poc1bl, Drer\LOC100334784, Drer\LOC100535692, Drer\galnt9, Drer\LOC101886587, Drer\LOC101882942, Drer\galnt6, Drer\galnt8b, Drer\galnt18b, Drer\galnt16, Drer\galnt13, Drer\si:ch211-15e22.3, Drer\galnt7, Drer\galnt11, Drer\galnt1, Drer\LOC103910015, Drer\galnt3, Drer\galnt10" - "Cele\gly-9, Cele\gly-10, Cele\gly-3, Cele\gly-11, Cele\gly-7, Cele\gly-6" "Xtro\galnt12, Xtro\galnt2, Xtro\galnt16, Xtro\galnt14, Xtro\galnt1, Xtro\galnt7, Xtro\galnt6.1, Xtro\galnt10, Xtro\galnt4, Xtro\galnt9, Xtro\wbscr17, Xtro\galnt15, Xtro\galnt13" "Mmus\Galnt14, Mmus\Galnt2, Mmus\Galnt16, Mmus\Galnt12, Mmus\Galnt15, Mmus\Galntl5, Mmus\Wbscr17, Mmus\Galnt3, Mmus\Galntl6, Mmus\Galnt5, Mmus\Galnt18, Mmus\Galnt1, Mmus\Galnt4, Mmus\Galnt6, Mmus\Galnt9, Mmus\Galnt13, Mmus\Galnt7, Mmus\Galnt10, Mmus\Galnt11" "Hsap\GALNT3, Hsap\GALNT15, Hsap\GALNT11, Hsap\GALNT13, Hsap\POC1B-GALNT4, Hsap\GALNT16, Hsap\GALNT1, Hsap\GALNT18, Hsap\GALNT10, Hsap\WBSCR17, Hsap\GALNT9, Hsap\GALNTL6, Hsap\GALNT4, Hsap\GALNT14, Hsap\GALNT12, Hsap\GALNT8, Hsap\GALNT5, Hsap\GALNT7, Hsap\GALNT6, Hsap\GALNT2, Hsap\GALNTL5" "visible,viable,lethal,partially lethal - majority die,recessive,fertile" "wing blade,wing disc" FBgn0052733 CR32733 - http://flybase.org/reports/FBgn0052733 pseudogene_attribute - - - "CG32733, CR32733" - CR32733 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259671 B1522 - http://flybase.org/reports/FBgn0259671 gene - - - B1522 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,mediproboscis,proboscis" FBgn0052528 parvin parvin http://flybase.org/reports/FBgn0052528 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR028433 actin binding ; GO:0003779 | inferred from sequence or structural similarity actin cytoskeleton reorganization ; GO:0031532 | inferred from electronic annotation with InterPro:IPR028433 cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR028433 muscle attachment ; GO:0016203 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype focal adhesion ; GO:0005925 | inferred from direct assay "CG32528, CG12533, parvin" "IPR001715:Calponin homology domain, IPR028433:Parvin" CG32528 11-Aug-17 DroID_v2017_08 "Drer\parvb, Drer\slc25a6, Drer\parvab, Drer\si:dkey-251i10.1, Drer\parvg, Drer\parvaa, Drer\slc25a5, Drer\slc25a4" - "Cele\pat-6, Cele\R07E3.4, Cele\F25B4.7, Cele\ant-1.3, Cele\ant-1.4" "Xtro\slc25a4, Xtro\parvb, Xtro\slc25a5" "Mmus\Slc25a5, Mmus\Slc25a31, Mmus\Slc25a4, Mmus\Parvb, Mmus\Parva, Mmus\Parvg" "Hsap\PARVB, Hsap\PARVA, Hsap\PARVG, Hsap\SLC25A31, Hsap\SLC25A4, Hsap\SLC25A6, Hsap\SLC25A5" "viable,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,flight defective,lethal,small body,lethal - all die before end of larval stage,some die during larval stage" "wing,embryonic/larval somatic muscle" FBgn0060418 l(3)S129217b lethal (3) S129217b http://flybase.org/reports/FBgn0060418 gene - - - "1292/17, l(3)S129217b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0259978 vlc vulcan http://flybase.org/reports/FBgn0259978 protein_coding_gene - signaling ; GO:0023052 | inferred from electronic annotation with InterPro:IPR005026 - "CG8390, l(2)07022, anon-WO0118547.98, vlc, X, anon-41Fa" IPR005026:SAPAP family CG8390 11-Aug-17 DroID_v2017_08 "Drer\LOC796210, Drer\dlgap4a, Drer\dlgap5, Drer\dlgap2a, Drer\dlgap3, Drer\dlgap1b, Drer\dlgap4b, Drer\dlgap1a" - Cele\W03A5.4 "Xtro\dlgap1, Xtro\dlgap2, Xtro\dlgap3, Xtro\dlgap5, Xtro\dlgap4" "Mmus\Dlgap2, Mmus\Dlgap5, Mmus\Dlgap3, Mmus\Dlgap4, Mmus\Dlgap1" "Hsap\DLGAP4, Hsap\DLGAP5, Hsap\DLGAP1, Hsap\DLGAP2, Hsap\DLGAP3" " embryonic stage | 3.5 hr , larval stage && pupal stage " " cephalic furrow

, ventral furrow

" FBgn0065446 l(2)SH1419 lethal (2) SH1419 http://flybase.org/reports/FBgn0065446 gene - - - "l(2)SH1419, l(2)SH2 1419" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266034 CR44799 - http://flybase.org/reports/FBgn0266034 non_protein_coding_gene - - - "CR44799, lincRNA.71" - CR44799 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030514 CG9941 - http://flybase.org/reports/FBgn0030514 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:20254 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:20254 cellular_component ; GO:0005575 | no biological data available "x93, A, CG9941" "IPR001841:Zinc finger, RING-type" CG9941 11-Aug-17 DroID_v2017_08 "Drer\cgrrf1, Drer\rnf26, Drer\mgrn1a, Drer\mgrn1b, Drer\si:dkey-49c17.3" - Cele\C11H1.3 "Xtro\rnf157, Xtro\cgrrf1, Xtro\mgrn1" "Mmus\Mgrn1, Mmus\Cgrrf1, Mmus\Rnf157" "Hsap\CGRRF1, Hsap\RNF157, Hsap\MGRN1" viable heart primordium FBgn0013233 E(var)1847 E(var)1847 http://flybase.org/reports/FBgn0013233 - gene - - - E(var)1847 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0039337 MED28 Mediator complex subunit 28 http://flybase.org/reports/FBgn0039337 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | contributes_to inferred by curator from GO:0016592 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with HGNC:2372 neurogenesis ; GO:0022008 | inferred from mutant phenotype mediator complex ; GO:0016592 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Med28, Med23, dMED23, CG5121, BcDNA:GM31575, MED28" "IPR021640:Mediator complex, subunit Med28" CG5121 11-Aug-17 DroID_v2017_08 "Drer\alkbh6, Drer\med28" - Cele\B0564.2 "Xtro\alkbh6, Xtro\med28" Mmus\Med28 "Hsap\MED28, Hsap\ALKBH6" "lethal,neuroanatomy defective" ganglion mother cell FBgn0035851 MED24 Mediator complex subunit 24 http://flybase.org/reports/FBgn0035851 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from biological aspect of ancestor with PANTHER:PTN000984923 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype positive regulation of programmed cell death ; GO:0043068 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity pupal development ; GO:0035209 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype inferred from genetic interaction with Eip74EF regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype mediator complex ; GO:0016592 | inferred from direct assay mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000984923 mediator complex ; GO:0016592 | inferred from sequence or structural similarity "med24, psg5, Trap100, Med24, dTRAP100, CG7999, MED24, l(3)psg5" "IPR021429:Mediator complex, subunit Med24, N-terminal" CG7999 11-Aug-17 DroID_v2017_08 Drer\med24 - - Xtro\med24 Mmus\Med24 Hsap\MED24 "lethal,some die during P-stage,lethal - all die before end of P-stage,recessive,lethal - all die before end of pupal stage,some die during pupal stage,cell death defective,viable,visible,planar polarity defective" "embryonic/larval salivary gland,trichogen cell" DRSC10944 K 0.55252296 0.883296825 -0.498704461 0.373143108 1.08801076 1.877401702 FBgn0053272 CG33272 - http://flybase.org/reports/FBgn0053272 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "HDC09626, CG17981, CG33272" - CG33272 11-Aug-17 DroID_v2017_08 - - - - - - DRSC09116 K 0.7754584 1.747758487 FBgn0035518 CG15011 - http://flybase.org/reports/FBgn0035518 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000967, InterPro:IPR001841 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from biological aspect of ancestor with PANTHER:PTN000270822 zinc ion binding ; GO:0008270 | inferred from sequence model RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000270822" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000967 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000270822" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000270822 "CG15011, cg15011" "IPR000967:Zinc finger, NF-X1-type, IPR034078:Transcription factor NFX1 family, IPR019786:Zinc finger, PHD-type, conserved site" CG15011 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-10f23.2, Drer\nfxl1" Scer\FAP1 Cele\nfx-1 "Xtro\nfxl1, Xtro\nfx1" "Mmus\Nfx1, Mmus\Nfxl1" "Hsap\NFX1, Hsap\NFXL1" "viable,fertile" DRSC08464 K 0.507570659 -1.473295953 0.008633084 -0.033261132 0.896629729 -2.09806905 FBgn0045039 l(2)Hr45-cII lethal (2) Hr45-cII http://flybase.org/reports/FBgn0045039 gene - - - l(2)Hr45-cII - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0067865 Mod(Prat:bw)Y-1 Mod(Prat:bw)Y-1 http://flybase.org/reports/FBgn0067865 gene - - - "Mod-Y-1, Mod(Prat:bw)Y-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - suppressor of variegation FBgn0029590 CG14811 - http://flybase.org/reports/FBgn0029590 protein_coding_gene - - - CG14811 - CG14811 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043863 pf-3 pairing failure-3 http://flybase.org/reports/FBgn0043863 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG3, pf-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262316 mir-986 mir-986 stem loop http://flybase.org/reports/FBgn0262316 miRNA_gene - muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-986, miR-986, mir-986, CR43023, dme-miR-986-3p, dme-miR-986" - CR43023 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020808 mfs(3)D4 mfs(3)D4 http://flybase.org/reports/FBgn0020808 - gene - - - "3-D4, mfs(3)D4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile,chemical sensitive" FBgn0023115 anon-10As anon-10As http://flybase.org/reports/FBgn0023115 - gene - - - "12, anon-10As" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065451 l(2)SH1400 lethal (2) SH1400 http://flybase.org/reports/FBgn0065451 gene - - - "l(2)SH1400, l(2)SH2 1400" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000412 D1 D1 chromosomal protein http://flybase.org/reports/FBgn0000412 - protein_coding_gene satellite DNA binding ; GO:0003696 | inferred from direct assay AT DNA binding ; GO:0003680 | inferred from direct assay - nucleosome ; GO:0000786 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "CG9745, RE69409, EP(3)0473, dD1, D1, HMGI, dHMGx" "IPR017956:AT hook, DNA-binding motif" CG9745 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0052318 CG32318 - http://flybase.org/reports/FBgn0052318 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from biological aspect of ancestor with PANTHER:PTN000649234" chromosome segregation ; GO:0007059 | inferred from biological aspect of ancestor with PANTHER:PTN000649235 mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000649235 microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 "CR32318, CG32318, CG32318-PA" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001752:Kinesin motor domain" CG32318 11-Aug-17 DroID_v2017_08 "Drer\kif11, Drer\gins1" "Scer\PSF1, Scer\CIN8, Scer\KIP1" "Cele\bmk-1, Cele\psf-1" "Xtro\gins1, Xtro\kif11" "Mmus\Gins1, Mmus\Kif11, Mmus\Kif20a" "Hsap\GINS1, Hsap\KIF11, Hsap\KIF20A" FBgn0045046 fs(1)3 female sterile (1) 3 http://flybase.org/reports/FBgn0045046 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)3 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0036332 CG11261 - http://flybase.org/reports/FBgn0036332 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from sequence or structural similarity with Cul1 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000231993 ubiquitin protein ligase activity ; GO:0061630 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000231993 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000231993 protein catabolic process ; GO:0030163 | inferred from sequence or structural similarity with Cul1 cullin-RING ubiquitin ligase complex ; GO:0031461 | inferred from biological aspect of ancestor with PANTHER:PTN000231993 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with Cul1 "CUL6, CG11261, Cullin6" "IPR001373:Cullin, N-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016158:Cullin homology, IPR016159:Cullin repeat-like-containing domain, IPR019559:Cullin protein, neddylation domain" CG11261 11-Aug-17 DroID_v2017_08 "Drer\cacul1, Drer\cul3b, Drer\cul1a" "Scer\CUL3, Scer\CDC53, Scer\RTT101" "Cele\cul-3, Cele\cul-2, Cele\cul-4, Cele\cul-1, Cele\cul-6" Xtro\cul1 "Mmus\Cul3, Mmus\Cul1, Mmus\Cacul1" "Hsap\CUL1, Hsap\CUL3, Hsap\CACUL1" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0027952 mei(2)yh92 mei(2)yh92 http://flybase.org/reports/FBgn0027952 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - "mei-yh92, mei(2)yh92" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "meiosis & nuclear chromosome,meiotic metaphase I,meiotic anaphase I | male" FBgn0086319 JV282 - http://flybase.org/reports/FBgn0086319 gene - - - JV282 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0037515 Sp7 Serine protease 7 http://flybase.org/reports/FBgn0037515 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 positive regulation of melanization defense response ; GO:0035008 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model melanization defense response ; GO:0035006 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from direct assay "CG3066, MP2, SP7, proPO-AE, anon-Ryu, Sp7, PAE1, sp7, Sp 7, PAE" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG3066 11-Aug-17 DroID_v2017_08 "Drer\st14b, Drer\masp2" - "Cele\try-1, Cele\try-3" - Mmus\F10 - "viable,melanotic mass phenotype,lethal - all die before end of pupal stage,some die during pupal stage,lethal,wound healing defective,immune response defective,partially" "melanotic mass | larval stage,melanotic mass | P-stage,melanotic mass | adult stage,melanotic mass,embryonic/larval hemolymph | third instar larval stage" FBgn0022288 l(2)09851 lethal (2) 09851 http://flybase.org/reports/FBgn0022288 "FBgn0022053, FBgn0033037" protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12792, l(2)k08138, l(2)09851, I(2)09851, GRWD1" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR022052:Histone-binding protein RBBP4, N-terminal" CG12792 11-Aug-17 DroID_v2017_08 "Drer\grwd1, Drer\wdr59" "Scer\WTM2, Scer\WTM1, Scer\RRB1, Scer\UME1" Cele\Y54H5A.1 Xtro\grwd1 "Mmus\Wdr59, Mmus\Grwd1" Hsap\GRWD1 "lethal,recessive,viable,visible" trichogen cell FBgn0039783 PH4alphaNE2 prolyl-4-hydroxylase-alpha NE2 http://flybase.org/reports/FBgn0039783 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 cell migration ; GO:0016477 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 extracellular space ; GO:0005615 | inferred from sequence model "CG9720, PH4alphaNE2" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR019734:Tetratricopeptide repeat" CG9720 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\zgc:158254, Drer\p4ha3, Drer\zgc:152670, Drer\p4ha1a, Drer\p4htm" - "Cele\dpy-18, Cele\phy-4, Cele\phy-3, Cele\C14E2.4, Cele\Y43F8B.19" "Xtro\p4ha1, Xtro\p4ha2, Xtro\p4ha3" "Mmus\P4htm, Mmus\P4ha3, Mmus\P4ha2, Mmus\P4ha1" "Hsap\P4HTM, Hsap\P4HA1, Hsap\P4HA2, Hsap\P4HA3" "partially lethal - majority die,some die during pupal stage" FBgn0038951 CG5380 - http://flybase.org/reports/FBgn0038951 protein_coding_gene RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000299878 DNA-directed RNA polymerase activity ; GO:0003899 | non-traceable author statement transcription from RNA polymerase III promoter ; GO:0006383 | inferred from electronic annotation with InterPro:IPR007832 neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000299878 CG5380 "IPR007832:RNA polymerase Rpc34, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016049:RNA polymerase Rpc34-like" CG5380 11-Aug-17 DroID_v2017_08 Drer\polr3f Scer\RPC34 Cele\W09C3.4 Xtro\polr3f Mmus\Polr3f Hsap\POLR3F "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0265066 CR44177 - http://flybase.org/reports/FBgn0265066 non_protein_coding_gene - - - CR44177 - CR44177 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031171 CG1801 - http://flybase.org/reports/FBgn0031171 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 CG1801 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026082:ABC transporter A, ABCA" CG1801 11-Aug-17 DroID_v2017_08 "Drer\abca2, Drer\abca1b, Drer\abca1a, Drer\abca12, Drer\abch1, Drer\abca5, Drer\abca3b" "Scer\SNQ2, Scer\PDR18, Scer\PDR15, Scer\PDR10, Scer\PDR5, Scer\AUS1, Scer\PDR11, Scer\PDR12, Scer\YOL075C" "Cele\abt-5, Cele\ced-7" "Xtro\abca1, Xtro\abca2, Xtro\abca8, Xtro\abca4, Xtro\abca3, Xtro\abca9, Xtro\abca10" "Mmus\Abca17, Mmus\Abca12, Mmus\Abca1, Mmus\Abca7, Mmus\Abca3, Mmus\Abca16, Mmus\Abca6, Mmus\Abca13, Mmus\Abca2, Mmus\Abca4, Mmus\Abca14, Mmus\Abca8b, Mmus\Abca15, Mmus\Abca5, Mmus\Abca8a, Mmus\Abca9" "Hsap\ABCA12, Hsap\ABCA13, Hsap\ABCA9, Hsap\ABCA7, Hsap\ABCA2, Hsap\ABCA10, Hsap\ABCA1, Hsap\ABCA6, Hsap\ABCA8, Hsap\ABCA3, Hsap\ABCA5, Hsap\ABCA4" viable FBgn0002856 Acp26Ab Accessory gland protein 26Ab http://flybase.org/reports/FBgn0002856 - protein_coding_gene - mating behavior ; GO:0007617 | inferred from electronic annotation with InterPro:IPR008392 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "Acp26A, Acp26Aab, Mst26Ab, Mst26A, mst355b, mst 355b, msP355b, CG9024, Acp26Ab, Acp26a, Acp, acp26Ab" IPR008392:Drosophila accessory gland-specific peptide 26Ab CG9024 11-Aug-17 DroID_v2017_08 - - - - - - " pupal stage && adult stage , adult stage | male " male accessory gland

" adult stage | female , adult stage | male " " adult hemolymph

, male accessory gland

, male accessory gland main cell

, male accessory gland secondary cell

, genital chamber

" viable FBgn0067391 T:Mito-oat Mitochondrial presequence of oat http://flybase.org/reports/FBgn0067391 engineered_tag - - - "T:Mito-oat, T:mito1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085768 CR40712 - http://flybase.org/reports/FBgn0085768 rRNA_gene - - - CR40712 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001545 l(1)15Ab lethal (1) 15Ab http://flybase.org/reports/FBgn0001545 - gene - - - "l(1)k27e, k27e, l(1)15Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051510 CG31510 - http://flybase.org/reports/FBgn0051510 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN001128910 - - "CG10057, CG31510" - CG31510 11-Aug-17 DroID_v2017_08 "Drer\zgc:114104, Drer\zmat4a, Drer\znf346, Drer\zgc:171482, Drer\zmat4b, Drer\znf385b, Drer\zmat3, Drer\znf385a, Drer\znf385c" - - - "Mmus\Krcc1, Mmus\Zmat1, Mmus\Zfp346, Mmus\Zmat3, Mmus\Zfp385b, Mmus\Zmat4, Mmus\Zfp385a, Mmus\Zfp385c" "Hsap\ZNF385B, Hsap\ZNF385C, Hsap\KRCC1, Hsap\ZMAT4, Hsap\ZNF346, Hsap\ZNF385A, Hsap\ZMAT1, Hsap\ZMAT3, Hsap\ZNF385D" viable DRSC14182 E 0.654394879 0.184812793 2.264868038 0.439692902 0.608301879 0.882254829 FBgn0040114 l(2)AR-44 lethal (2) AR-44 http://flybase.org/reports/FBgn0040114 gene - - - l(2)AR-44 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0017414 cag cag http://flybase.org/reports/FBgn0017414 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" - - "CG12346, cag" "IPR007889:DNA binding HTH domain, Psq-type, IPR006600:HTH CenpB-type DNA-binding domain, IPR009057:Homeobox domain-like" CG12346 11-Aug-17 DroID_v2017_08 "Drer\pogza, Drer\LOC100150296, Drer\pogzb" Scer\PDC2 Cele\Y53G8AM.8 - "Mmus\Tigd4, Mmus\Pogk, Mmus\Jrkl, Mmus\Tigd2, Mmus\Pogz, Mmus\Tigd3, Mmus\Jrk, Mmus\Cenpb" "Hsap\CENPBD1, Hsap\JRKL, Hsap\TIGD2, Hsap\TIGD1, Hsap\TIGD6, Hsap\TIGD7, Hsap\CENPB, Hsap\POGK, Hsap\POGZ, Hsap\TIGD3, Hsap\TIGD4" "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0010591 Sply Sphingosine-1-phosphate lyase http://flybase.org/reports/FBgn0010591 "FBgn0034190, FBgn0044523" protein_coding_gene carboxy-lyase activity ; GO:0016831 | inferred from electronic annotation with InterPro:IPR002129 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 sphinganine-1-phosphate aldolase activity ; GO:0008117 | inferred from direct assay carboxylic acid metabolic process ; GO:0019752 | inferred from electronic annotation with InterPro:IPR002129 adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype sphingolipid catabolic process ; GO:0030149 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model "CG8946, SPL, spl, Spl, l(2)05091, anon-WO0142479.5, Sply, sply" "IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG8946 11-Aug-17 DroID_v2017_08 Drer\sgpl1 "Scer\DPL1, Scer\GAD1" "Cele\tag-38, Cele\Y104H12D.3, Cele\spl-1" Xtro\sgpl1 Mmus\Sgpl1 Hsap\SGPL1 "lethal,recessive,partially lethal - majority die,flightless,female sterile,partially,male sterile,increased cell death,viable,visible" "dorsal medial muscle,chaeta" FBgn0025519 fidipidine fidipidine http://flybase.org/reports/FBgn0025519 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available Golgi to plasma membrane transport ; GO:0006893 | inferred from biological aspect of ancestor with PANTHER:PTN000419639 cellular_component ; GO:0005575 | no biological data available "CG7773, fidipidine" IPR019159:Coiled-coil domain of unkwon function DUF2037 CG7773 11-Aug-17 DroID_v2017_08 Drer\ccdc93 - "Cele\C31E10.5, Cele\C16A11.2, Cele\C31E10.6" Xtro\ccdc93 Mmus\Ccdc93 Hsap\CCDC93 "viable,visible" trichogen cell DRSC07618 I -0.172290918 -1.92839258 -0.34420049 -1.074140426 0.081255897 -0.471123804 FBgn0266866 CR45327 - http://flybase.org/reports/FBgn0266866 non_protein_coding_gene - - - CR45327 - CR45327 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060603 l(3)S091603 lethal (3) S091603 http://flybase.org/reports/FBgn0060603 gene - - - "0916/03, l(3)S091603" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031608 CG15435 - http://flybase.org/reports/FBgn0031608 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG15435 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG15435 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259452 C211 - http://flybase.org/reports/FBgn0259452 gene - - - C211 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin,chaeta,ectopic" FBgn0042187 CG17234 - http://flybase.org/reports/FBgn0042187 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP113, CG17234" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG17234 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-78l4.5, Drer\zmp:0000001088, Drer\LOC560023" - "Cele\try-1, Cele\svh-1" - "Mmus\Prss53, Mmus\Prss36, Mmus\Klk1b5, Mmus\Klk1b8, Mmus\Klk1b3, Mmus\Klk14, Mmus\Egfbp2, Mmus\Prss40, Mmus\Klk1b9" "Hsap\CMA1, Hsap\PRSS53, Hsap\PRSS36" viable FBgn0031554 CG15418 - http://flybase.org/reports/FBgn0031554 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG15418 "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG15418 11-Aug-17 DroID_v2017_08 "Drer\spint1a, Drer\si:dkeyp-73b11.8, Drer\si:dkey-117n7.5, Drer\spint2, Drer\col6a4a, Drer\ambp, Drer\spint1b, Drer\tfpi2, Drer\tfpia" - Cele\B0222.5 "Xtro\spint1, Xtro\tfpi2, Xtro\spint2, Xtro\ambp" "Mmus\Wfdc6b, Mmus\Spint5, Mmus\Ambp, Mmus\Spint4, Mmus\Spint1, Mmus\Tfpi2, Mmus\Spint2, Mmus\Wfdc8, Mmus\Spint3, Mmus\Wfdc6a, Mmus\Tfpi, Mmus\Eppin" "Hsap\AMBP, Hsap\SPINT4, Hsap\SPINT1, Hsap\TFPI2, Hsap\SPINT2, Hsap\EPPIN-WFDC6, Hsap\TFPI, Hsap\WFDC8, Hsap\WFDC6, Hsap\SPINT3" FBgn0021793 l(2)k17026 lethal (2) k17026 http://flybase.org/reports/FBgn0021793 - gene - - - l(2)k17026 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046664 anon-38C.35 anon-38C.35 http://flybase.org/reports/FBgn0046664 gene - - - "38C.35, anon-38C.35" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001473 l(1)9Ec lethal (1) 9Ec http://flybase.org/reports/FBgn0001473 - gene - - - l(1)9Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037551 Gie GTPase indispensable for equal segregation of chromosomes http://flybase.org/reports/FBgn0037551 protein_coding_gene alpha-tubulin binding ; GO:0043014 | inferred from sequence or structural similarity with UniProtKB:Q9NVJ2 beta-tubulin binding ; GO:0048487 | inferred from sequence or structural similarity with UniProtKB:Q9NVJ2 GTP binding ; GO:0005525 | inferred from sequence or structural similarity with UniProtKB:Q9NVJ2 GDP binding ; GO:0019003 | inferred from sequence or structural similarity with UniProtKB:Q9NVJ2 "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR003579, InterPro:IPR024156 sister chromatid segregation ; GO:0000819 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from mutant phenotype" extrinsic component of lysosome membrane ; GO:0032419 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9NVJ2 midbody ; GO:0030496 | inferred from sequence or structural similarity with UniProtKB:Q9NVJ2 spindle midzone ; GO:0051233 | inferred from sequence or structural similarity with UniProtKB:Q9NVJ2 lysosome ; GO:0005764 | inferred from direct assay "BcDNA:LD29185, Gie, CG7891, Arl8, Q9VHV5" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR024156:Small GTPase superfamily, ARF type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7891 11-Aug-17 DroID_v2017_08 "Drer\arl8ba, Drer\arl8bb, Drer\arl8a" Scer\ARL1 Cele\arl-8 "Xtro\arl8b, Xtro\arl8a, Xtro\arl10b" "Mmus\Arl8b, Mmus\Arl8a" "Hsap\ARL8A, Hsap\ARL8B" "partially lethal - majority die,some die during pupal stage" FBgn0004106 Cdk1 Cyclin-dependent kinase 1 http://flybase.org/reports/FBgn0004106 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity with SGD:S000000364 inferred from genetic interaction with SGD:S000000364 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9I7I0 protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" histone phosphorylation ; GO:0016572 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 regulation of meiotic cell cycle ; GO:0051445 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 meiotic G2/MI transition ; GO:0008315 | traceable author statement G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from genetic interaction with SGD:S000000364 male meiosis I ; GO:0007141 | traceable author statement regulation of protein localization ; GO:0032880 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | traceable author statement mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype spermatogonial cell division ; GO:0007284 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 male meiosis ; GO:0007140 | inferred from mutant phenotype mitotic G2/M transition checkpoint ; GO:0044818 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from genetic interaction with SGD:S000000364 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 mitotic spindle ; GO:0072686 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 microtubule associated complex ; GO:0005875 | inferred from direct assay "Cdk1, DmCdc2, cdk1, Cdc2, CDK1, CG5363, Dmcdc2, CDK1/CDC2, DmCdk1, cdc, CDCDm, Dm cdc2, Dcdc2, CDC2, group 4, cdc2Dm, l(2)31Eh, cdc2, dCdk1, 5363, Cdk-1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG5363 11-Aug-17 DroID_v2017_08 "Drer\cdk2, Drer\cdk21, Drer\cdk5, Drer\cdk1, Drer\si:dkey-166c18.1, Drer\cdk4, Drer\cdk16, Drer\cdk14, Drer\cdk17, Drer\cdk6, Drer\LOC100536316, Drer\cdk15" "Scer\CDC28, Scer\CTK1, Scer\CAK1, Scer\PHO85" "Cele\cdk-2, Cele\cdk-5, Cele\cdk-1, Cele\ZC123.4" "Xtro\cdk18, Xtro\cdk15, Xtro\cdk16, Xtro\cdk6, Xtro\cdk5, Xtro\cdk2, Xtro\cdk17, Xtro\cdk4, Xtro\cdk14, Xtro\cdk1" "Mmus\Cdk2, Mmus\Cdk5, Mmus\Cdk4, Mmus\Cdk1, Mmus\E030030I06Rik, Mmus\Cdk6, Mmus\Cdk15, Mmus\Cdk16, Mmus\Cdk17, Mmus\Cdk14, Mmus\Cdk18" "Hsap\CDK5, Hsap\CDK1, Hsap\CDK18, Hsap\CDK14, Hsap\CDK3, Hsap\CDK15, Hsap\CDK4, Hsap\CDK17, Hsap\CDK6, Hsap\CDK2, Hsap\CDK16" " embryonic stage | early , embryonic stage , adult stage | female " embryonic central nervous system

"lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,recessive,increased cell death,mitotic cell cycle defective,radiation sensitive,heat sensitive,increased cell size,decreased cell number,wild-type,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal - all die during pharate adult stage,size defective,lethal - all die during pupal stage,somatic clone,cell autonomous,cell non-autonomous,female sterile" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,larval outer optic anlage,larval optic anlage,somatic clone,synapse,neuromuscular junction,ganglion mother cell GMC4-2a,wing disc,posterior | third instar larval stage,sensory mother cell | third instar larval stage,type I neuroblast | larval stage,A1-7 dorsal acute muscle 1,ectopic,RP2 motor neuron,embryonic neuroblast,polar body nucleus,spindle,centriole,nuclear pore | heat sensitive,annulate lamellae | heat sensitive,imaginal disc,wing margin,wing disc | third instar larval stage,eye,chromosomepros.PU,embryonic/larval brain,anterior compartment,adult abdomen,heat sensitive,embryonic/larval optic lobe,histoblast & nucleus | conditional ts,tormogen cell,trichogen cell,oocyte,temperature conditional,trichome,chaeta,wing,wing cell,central nervous system,embryonic/larval salivary gland,ganglion mother cell GMC4-2a & spindle,embryonic neuroblast & spindle,secondary spermatogonium,mitotic cell cycle,cyst cell,pole cell,optic lobe,histoblast,wing hair" DRSC03504 IEK -2.679754603 -2.560547216 -1.929005038 -2.429830051 6.678636131 7.757581633 FBgn0259396 C756 - http://flybase.org/reports/FBgn0259396 gene - - - C756 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0037025 Spc105R Spc105-related http://flybase.org/reports/FBgn0037025 protein_coding_gene - kinetochore assembly ; GO:0051382 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype attachment of spindle microtubules to kinetochore ; GO:0008608 | inferred from mutant phenotype condensed chromosome outer kinetochore ; GO:0000940 | inferred from direct assay "CG11451, spc105R, Spc105, Spc105R, dmSpc105R, dmKNL-1, DmSpc105, KNL1" - CG11451 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,recessive,mitotic cell cycle defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,nucleus,embryonic/larval central nervous system,nucleusri-XT1),spindlemat.‘±Tub67C.THsimVP16,embryonic/larval neuroblast,ganglion mother cell" DRSC11663 IE -3.202282337 -1.70816307 -0.330138905 -3.103978922 0.828515691 0.208099361 FBgn0261453 scaRNA:MeU2-C41 small Cajal body-specific RNA : MeU2-C41 http://flybase.org/reports/FBgn0261453 snoRNA_gene snRNA 2'-O-ribose methylation guide activity ; GO:0030563 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "mgU2-41, scaRNA:lds-a, scaRNA:mgU2-41, scaRNA:MeU2-C41" - CR43570 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266595 CR45120 - http://flybase.org/reports/FBgn0266595 non_protein_coding_gene - - - CR45120 - CR45120 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005024 depilated depilated http://flybase.org/reports/FBgn0005024 - gene - - - "depilated, dpt" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable" "macrochaeta & adult thorax,macrochaeta & adult head" FBgn0084034 CG41474 - http://flybase.org/reports/FBgn0084034 protein_coding_gene - - - CG41474 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069323 X-158-33 X-158-33 http://flybase.org/reports/FBgn0069323 gene molecular_function ; GO:0003674 | no biological data available oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-158-33 - - 11-Aug-17 DroID_v2017_08 - - - - - - "dorsal appendage,germline clone,non-rescuable maternal effect,egg" FBgn0261055 Sfp26Ad Seminal fluid protein 26Ad http://flybase.org/reports/FBgn0261055 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp26Ad, CG42603" - CG42603 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024618 ms(1)S21 ms(1)S21 http://flybase.org/reports/FBgn0024618 - gene - - - ms(1)S21 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0010422 TfIIS RNA polymerase II elongation factor http://flybase.org/reports/FBgn0010422 "FBgn0000474, FBgn0001982" protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR006289 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR017890 transcription factor activity, core RNA polymerase II recruiting ; GO:0001139 | inferred from sequence or structural similarity with SGD:S000003011" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR006289 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from sequence or structural similarity with SGD:S000003011" nucleus ; GO:0005634 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000003011 "TFIIS, l(2)35Cf, l(2)35cF, DmS-II, BG:DS00929.12, TFIISA, TFS-II, l35Cf, br52, l(2)br52, RnpSII, DmSII, CG3710, TfIIS" "IPR001222:Zinc finger, TFIIS-type, IPR003617:Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type, IPR003618:Transcription elongation factor S-II, central domain, IPR006289:Transcription elongation factor, TFIIS, IPR017923:Transcription factor IIS, N-terminal" CG3710 11-Aug-17 DroID_v2017_08 "Drer\tcea1, Drer\tceanc2, Drer\crsp7, Drer\tcea2, Drer\tcea3, Drer\si:dkey-33g10.1" Scer\DST1 "Cele\mdt-26, Cele\T24H10.1" "Xtro\tceanc, Xtro\tceanc2, Xtro\tcea3, Xtro\tcea1, Xtro\med26" "Mmus\Stra6l, Mmus\Tceanc, Mmus\Tceanc2, Mmus\Tcea1, Mmus\Med26, Mmus\Tcea2, Mmus\Tcea3" "Hsap\MED26, Hsap\TCEANC2, Hsap\TCEA3, Hsap\TCEA2, Hsap\TCEANC, Hsap\TCEA1" "lethal,recessive,viable" wing FBgn0045034 ultA ultrahair A http://flybase.org/reports/FBgn0045034 gene molecular_function ; GO:0003674 | no biological data available chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype growth ; GO:0040007 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "uhr, ultA" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing hair,somatic clone,ectopic,wing,wing margin bristle" FBgn0001780 l(1)M66 lethal (1) M66 http://flybase.org/reports/FBgn0001780 - gene - - - l(1)M66 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0052260 CG32260 - http://flybase.org/reports/FBgn0052260 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "BcDNA:GH24648, CG32260" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG32260 11-Aug-17 DroID_v2017_08 "Drer\zgc:171592, Drer\zgc:112285, Drer\zgc:92745, Drer\zgc:154142, Drer\zgc:92511, Drer\ctrb1, Drer\si:dkey-238d18.3, Drer\ela2l, Drer\LOC562139, Drer\ela3l, Drer\ctrl, Drer\zgc:112302, Drer\zgc:112160, Drer\ela2, Drer\zgc:112368, Drer\zgc:92041, Drer\si:dkey-57c15.4" - "Cele\svh-1, Cele\try-1, Cele\try-3" "Xtro\ctrb1, Xtro\ctrc, Xtro\LOC100135144, Xtro\ctrb2, Xtro\tmprss12, Xtro\cela3a, Xtro\cela2a" "Mmus\Cela3a, Mmus\Cela1, Mmus\Tmprss13, Mmus\Cela2a, Mmus\Ctrc, Mmus\Ctrl, Mmus\Cela3b, Mmus\Ctrb1" "Hsap\CELA3B, Hsap\CELA2A, Hsap\CELA1, Hsap\CTRC, Hsap\CTRL, Hsap\CTRB1, Hsap\PRSS12, Hsap\CELA2B, Hsap\CTRB2, Hsap\CELA3A" viable FBgn0259549 GG01287 - http://flybase.org/reports/FBgn0259549 gene - - - GG01287 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing" FBgn0022768 Pp2C1 Protein phosphatase 2C http://flybase.org/reports/FBgn0022768 FBgn0066851 protein_coding_gene cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR000222 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003952 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000000329 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003952 protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000000329 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000329 "PP2C, CG2984, PP2C1, dpp2c1, anon-WO03040301.132, Pp2C1" "IPR015655:Protein phosphatase 2C family, IPR000222:PPM-type phosphatase, divalent cation binding, IPR001932:PPM-type phosphatase domain, IPR003952:Fumarate reductase/succinate dehydrogenase, FAD-binding site, IPR015943:WD40/YVTN repeat-like-containing domain" CG2984 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-149b19.3, Drer\ppm1k, Drer\ppm1lb, Drer\ilkap, Drer\ppm1f, Drer\ppm1db, Drer\tab1, Drer\ppm1da, Drer\ppm1e, Drer\ppm1la" "Scer\PTC4, Scer\PTC6, Scer\PTC1" Cele\Y54F10BM.1 "Xtro\ppm1f, Xtro\ppm1e, Xtro\tab1, Xtro\ppm1l, Xtro\ilkap, Xtro\ppm1d, Xtro\ppm1k" "Mmus\Ilkap, Mmus\Pp2d1, Mmus\Ppm1f, Mmus\Ppm1l, Mmus\Ppm1e, Mmus\Tab1, Mmus\Ppm1k, Mmus\Ppm1d" "Hsap\ILKAP, Hsap\PP2D1, Hsap\PPM1F, Hsap\PPM1L, Hsap\PPM1E, Hsap\TAB1, Hsap\PPM1D, Hsap\PPM1K" "viable,visible" trichogen cell FBgn0042189 CG17376 - http://flybase.org/reports/FBgn0042189 protein_coding_gene - - - "bs29c06.y1, CG18461, CG17376" "IPR017896:4Fe-4S ferredoxin-type, iron-sulphur binding domain" CG17376 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028587 l(?)AR111 lethal (?) AR111 http://flybase.org/reports/FBgn0028587 gene - - - l(?)AR111 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013517 l(1)XWL lethal (1) XWL http://flybase.org/reports/FBgn0013517 - gene - - - "XWL, l(1)XWL" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261670 CG42725 - http://flybase.org/reports/FBgn0261670 protein_coding_gene - - - CG42725 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260083 2L2181 - http://flybase.org/reports/FBgn0260083 gene - - - 2L2181 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0027780 U26 U26 http://flybase.org/reports/FBgn0027780 - protein_coding_gene acid-thiol ligase activity ; GO:0016878 | inferred from sequence or structural similarity with UniProtKB:Q4G176 fatty acid metabolic process ; GO:0006631 | inferred from sequence or structural similarity with UniProtKB:Q4G176 - "CG13401, U26" "IPR018391:Pyrrolo-quinoline quinone beta-propeller repeat, IPR000873:AMP-dependent synthetase/ligase, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR002372:Pyrrolo-quinoline quinone repeat, IPR025666:Pyrrolo-quinoline quinone-like domain" CG13401 11-Aug-17 DroID_v2017_08 Drer\aasdh Scer\LYS2 "Cele\W09D6.1, Cele\Y66D12A.14" Xtro\aasdh Mmus\Aasdh Hsap\AASDH viable FBgn0050151 CG30151 - http://flybase.org/reports/FBgn0050151 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE70748, CG30151" - CG30151 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039504 CG14260 - http://flybase.org/reports/FBgn0039504 protein_coding_gene - adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - CG14260 "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain" CG14260 11-Aug-17 DroID_v2017_08 Drer\klhl41b - Cele\hpo-9 Xtro\klhl41 - - viable "indirect flight muscle,myofibrilMef2.PR" DRSC14755 E 0.634951801 0.607672585 0.839170757 1.558672 1.102049242 -0.667776084 FBgn0038952 CG7069 - http://flybase.org/reports/FBgn0038952 protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 potassium ion binding ; GO:0030955 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 pyruvate kinase activity ; GO:0004743 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 pyruvate kinase activity ; GO:0004743 | inferred from sequence or structural similarity with SGD:S000000036" glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 glycolytic process ; GO:0006096 | inferred from sequence or structural similarity with SGD:S000000036 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with SGD:S000000036 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000036 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with SGD:S000000036 CG7069 "IPR001697:Pyruvate kinase, IPR011037:Pyruvate kinase-like, insert domain, IPR018209:Pyruvate kinase, active site, IPR015813:Pyruvate/Phosphoenolpyruvate kinase-like domain, IPR015793:Pyruvate kinase, barrel, IPR015795:Pyruvate kinase, C-terminal" CG7069 11-Aug-17 DroID_v2017_08 "Drer\pkmb, Drer\pkma, Drer\pklr" "Scer\PYK2, Scer\CDC19" "Cele\pyk-2, Cele\pyk-1" "Xtro\pklr, Xtro\pkm" "Mmus\Pklr, Mmus\Pkm" "Hsap\PKLR, Hsap\PKM" viable FBgn0085820 CR41610 - http://flybase.org/reports/FBgn0085820 non_protein_coding_gene - - - CR41610 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025938 ci::pan ci::pan http://flybase.org/reports/FBgn0025938 - engineered_fusion_gene - - - ci::pan - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing margin bristle,wing vein L2,wing vein L3,wing vein L4,wing,anterior" FBgn0031716 CG14015 - http://flybase.org/reports/FBgn0031716 protein_coding_gene "hydrolase activity, acting on glycosyl bonds ; GO:0016798 | inferred from electronic annotation with InterPro:IPR026071" - - CG14015 IPR026071:Glycosyl hydrolase family 99 CG14015 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-30b16.2, Drer\manea" - - "Xtro\manea, Xtro\manea" "Mmus\Maneal, Mmus\Manea" "Hsap\MANEAL, Hsap\MANEA" "viable,visible" trichogen cell FBgn0050222 CG30222 - http://flybase.org/reports/FBgn0050222 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15672, CG12709, CG30222" - CG30222 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004919 gol goliath http://flybase.org/reports/FBgn0004919 "FBgn0004375, FBgn0004899" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from sequence or structural similarity with godzilla mesoderm formation ; GO:0001707 | inferred from expression pattern protein ubiquitination ; GO:0016567 | inferred from mutant phenotype nucleus ; GO:0005634 | non-traceable author statement endosome ; GO:0005768 | inferred from direct assay "g1, meso, anon-G1, CG2679, gol, Gol, dgol" "IPR001841:Zinc finger, RING-type, IPR003137:PA domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2679 11-Aug-17 DroID_v2017_08 "Drer\rnf11b, Drer\LOC100536511, Drer\rnf11a, Drer\rnf181, Drer\rnf32, Drer\wu:fb39e10, Drer\rnf150, Drer\si:dkey-51a16.9, Drer\rnf215, Drer\znrf3, Drer\rnf38, Drer\rlim, Drer\rnf126, Drer\rnf44, Drer\rnf24, Drer\rnf150a, Drer\zswim2, Drer\rnf6, Drer\rnf165a, Drer\si:ch1073-392o20.1, Drer\zgc:175214, Drer\rnf165b, Drer\rnf128a, Drer\rnf103, Drer\si:ch211-81a5.1, Drer\rnf111, Drer\pja2, Drer\rnf115, Drer\rnf130" "Scer\YBR062C, Scer\ASR1" Cele\H10E21.5 "Xtro\rnf38, Xtro\rnf115, Xtro\rnf126, Xtro\chmp3, Xtro\rnf150, Xtro\rnf11, Xtro\rnf149, Xtro\rlim, Xtro\rnf44, Xtro\rnf111, Xtro\rnf181, Xtro\rnf32, Xtro\znrf3, Xtro\pja2, Xtro\rnf24, Xtro\rnf11.2" "Mmus\4930595M18Rik, Mmus\Rnf115, Mmus\Rnf24, Mmus\Rnf181, Mmus\Rnf130, Mmus\Rnf165, Mmus\Rnf128, Mmus\Rnf150, Mmus\Rnf111, Mmus\Znrf3, Mmus\Rnf32, Mmus\Pja1, Mmus\Rnf44, Mmus\Rnf126, Mmus\Rnf43, Mmus\Rnf103, Mmus\Rnf38, Mmus\Zswim2, Mmus\Rnf149, Mmus\Rnf133, Mmus\Rnf122, Mmus\Rnf215, Mmus\Rlim, Mmus\Pja2, Mmus\Rnf6, Mmus\Rnf148, Mmus\Rnf11" "Hsap\RNF24, Hsap\RNF148, Hsap\RNF165, Hsap\RNF122, Hsap\RNF149, Hsap\RNF115, Hsap\RNF38, Hsap\RNF215, Hsap\RNF103, Hsap\RNF6, Hsap\RNF128, Hsap\RNF181, Hsap\RNF130, Hsap\RNF32, Hsap\RNF150, Hsap\RNF44, Hsap\PJA2, Hsap\RNF43, Hsap\RLIM, Hsap\RNF126, Hsap\ZNRF3, Hsap\RNF11, Hsap\ZSWIM2, Hsap\PJA1, Hsap\RNF133, Hsap\CHMP3, Hsap\RNF111" embryonic stage | stage 10-14 " pharyngeal muscle | presumptive

, mesoderm

" viable FBgn0016965 vm2 visible mutation-2 http://flybase.org/reports/FBgn0016965 - gene - - - vm2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0062673 EP2595 EP2595 http://flybase.org/reports/FBgn0062673 gene - - - "EP(2)2595, EP2595" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050496 CG30496 - http://flybase.org/reports/FBgn0050496 protein_coding_gene ubiquitin-protein transferase inhibitor activity ; GO:0055105 | inferred from biological aspect of ancestor with PANTHER:PTN001035248 ubiquitin protein ligase binding ; GO:0031625 | inferred from sequence or structural similarity with HGNC:14373 negative regulation of protein ubiquitination ; GO:0031397 | inferred from sequence or structural similarity with HGNC:14373 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001035248 cullin-RING ubiquitin ligase complex ; GO:0031461 | inferred from sequence or structural similarity with HGNC:14373 "CG1952, BcDNA:RE73310, anon-WO0118547.218, CG30496" "IPR019516:Glomulin/ALF4, IPR011989:Armadillo-like helical, IPR013877:YAP-binding/ALF4/Glomulin" CG30496 11-Aug-17 DroID_v2017_08 "Drer\glmna, Drer\glmnb" - - Xtro\glmn Mmus\Glmn Hsap\GLMN viable FBgn0038979 tHMG2 testis-enriched HMG-box-containing protein 2 http://flybase.org/reports/FBgn0038979 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay - cytoplasm ; GO:0005737 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "BcDNA:AT28425, CG7046, tHMG2, tHMG-2, thmg-2" IPR009071:High mobility group box domain CG7046 11-Aug-17 DroID_v2017_08 "Drer\hmgb2a, Drer\hmgb3b, Drer\tfam, Drer\hmg20a, Drer\ubtf, Drer\tox4a, Drer\hmgb1a, Drer\hmg20b, Drer\hmgb2b, Drer\hmgb1b, Drer\tox4b, Drer\hmgb3a, Drer\tox3, Drer\tox, Drer\ubtfl" "Scer\POB3, Scer\ABF2, Scer\IXR1, Scer\HMO1, Scer\NHP10, Scer\NHP6B, Scer\NHP6A" Cele\hmg-1.2 "Xtro\ubtf, Xtro\tox, Xtro\tox2, Xtro\tfam, Xtro\hmg20a, Xtro\tox4, Xtro\hmgb2, Xtro\hmg20b, Xtro\tox3, Xtro\hmgb3, Xtro\hmgb1" "Mmus\Hmg20b, Mmus\Tfam, Mmus\Hmgb4, Mmus\Hmg20a, Mmus\Tox2, Mmus\Hmgb2, Mmus\Tox3, Mmus\Hmgb3, Mmus\Hmgb1, Mmus\Tox, Mmus\Tox4, Mmus\Ubtfl1, Mmus\Ubtf" "Hsap\HMG20B, Hsap\HMGB1, Hsap\TOX3, Hsap\HMGB4, Hsap\UBTF, Hsap\HMGB2, Hsap\TOX4, Hsap\TFAM, Hsap\TOX, Hsap\HMG20A, Hsap\HMGB3, Hsap\TOX2" FBgn0032219 CG4995 - http://flybase.org/reports/FBgn0032219 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN001942979 acyl carnitine transmembrane transporter activity ; GO:0015227 | inferred from biological aspect of ancestor with PANTHER:PTN002377726 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 amino acid transport ; GO:0006865 | inferred from biological aspect of ancestor with PANTHER:PTN001942979 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG18626, CG4995" "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG4995 11-Aug-17 DroID_v2017_08 "Drer\slc25a48, Drer\LOC100329459, Drer\slc25a47a, Drer\slc25a20, Drer\slc25a15a, Drer\si:dkey-150i13.2, Drer\slc25a15b, Drer\slc25a45" "Scer\YMC2, Scer\ORT1, Scer\YMC1, Scer\CRC1" "Cele\R07B7.10, Cele\T10F2.2, Cele\slc-25A29, Cele\dif-1" "Xtro\slc25a47, Xtro\slc25a15, Xtro\slc25a45, Xtro\slc25a29, Xtro\slc25a20, Xtro\slc25a20.2, Xtro\slc25a48" "Mmus\Slc25a29, Mmus\Slc25a45, Mmus\Slc25a2, Mmus\Slc25a15, Mmus\Slc25a20, Mmus\Slc25a47, Mmus\Slc25a48" "Hsap\SLC25A20, Hsap\SLC25A48, Hsap\SLC25A2, Hsap\SLC25A45, Hsap\SLC25A15, Hsap\SLC25A29, Hsap\SLC25A47" viable FBgn0267485 CR45835 - http://flybase.org/reports/FBgn0267485 non_protein_coding_gene - - - CR45835 - CR45835 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053735 snmRNA:430:CR33735 snmRNA:430:CR33735 http://flybase.org/reports/FBgn0053735 non_protein_coding_gene - - - "CR33735, snmRNA:430:CR33735" - CR33735 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032867 CG15475 - http://flybase.org/reports/FBgn0032867 protein_coding_gene - - - "38D.19, CG15475" - CG15475 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001388 l(1)2Bt lethal (1) 2Bt http://flybase.org/reports/FBgn0001388 - gene - - - l(1)2Bt - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004644 hh hedgehog http://flybase.org/reports/FBgn0004644 "FBgn0000159, FBgn0001191, FBgn0002748, FBgn0002793, FBgn0011486, FBgn0011487, FBgn0044801" protein_coding_gene peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR001767 patched binding ; GO:0005113 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with ihog patched binding ; GO:0005113 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VM64 morphogen activity ; GO:0016015 | traceable author statement smoothened binding ; GO:0005119 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W3W5 "intein-mediated protein splicing=0016539 |... electronic annotation with InterPro:IPR006141 compound eye morphogenesis=0001745 | protein autoprocessing=0016540 |... germ cell migration=0008354 |... heart development=0007507 | segment polarity determination=0007367 | posterior head segmentation=0035289 | wing disc proximal/distal pattern formation=0007473 | genital disc development=0035215 | labial disc development=0035217 |... cytoneme assembly=0035231 |... segment polarity determination=0007367 |... expression pattern smoothened signaling pathway=0007224 |... with smo ventral midline development=0007418 |... anterior commissure morphogenesis=0021960 |... heart formation=0060914 |... R8 cell fate specification=0045464 | smoothened signaling pathway=0007224 | .. organ growth=0046620 | trunk segmentation=0035290 | leg disc morphogenesis=0007478 | .. transcription from RNA polymerase II promoter=0006357 | cell-cell signaling .. cell fate commitment=0045168 |... genital disc anterior/posterior pattern formation=0035224 |... expression pattern germ-line stem cell division=0042078 | wing disc anterior/posterior pattern formation=0048100 | positive .. transcription factor import into nucleus=0042993 |... mesoderm development=0007498 | eye morphogenesis=0048592 |... hindgut morphogenesis=0007442 |... Bolwig's organ morphogenesis=0001746 |... .. protein import into nucleus=0042306 |... imaginal disc growth=0007446 | compartment pattern specification=0007386 | analia development=0007487 | epidermis development=0008544 | negative .. protein ubiquitination=0031397 |... somatic stem cell division=0048103 | anterior/posterior lineage restriction, imaginal disc=0048099 | spiracle morphogenesis, open tracheal system=0035277 |... negative .. proteolysis=0045861 |... hindgut morphogenesis=0007442 | developmental pigmentation=0048066 | glial cell migration=0008347 |... .. mitotic cell cycle=0007346 |... imaginal disc pattern formation=0007447 | smoothened signaling pathway=0007224 | gonadal mesoderm development=0007506 |... segment polarity determination=0007367 | .. cell proliferation=0042127 | foregut morphogenesis=0007440 | pole cell migration=0007280 |... with disp inferred from with Hmgcr positive .. smoothened signaling pathway=0045880 | morphogenesis of larval imaginal disc epithelium=0016335 |... ovarian follicle cell development=0030707 | progression of morphogenetic furrow .. compound eye morphogenesis=0007458 |... expression pattern inferred frominferred from with dpp inferred from with h inferred from with sca genital disc development=0035215 |... segment polarity determination=0007367 |... ovarian follicle cell stalk formation=0030713 | open tracheal system development=0007424 | growth=0040007 | embryonic pattern specification=0009880 |... expression pattern germ cell attraction=0035232 | protein autoprocessing=0016540 |... inferred from heart development=0007507 | .. epithelial cell migration, open tracheal system=2000274 |... compound eye photoreceptor cell differentiation=0001751 | mucosal immune response=0002385 |... imaginal disc-derived wing vein specification=0007474 | positive .. hh target transcription factor activity=0007228 |... with fu inferred from with Su(fu) positive .. fibroblast growth factor receptor signaling pathway=0045743 |... anterior/posterior axis specification, embryo=0008595 | epithelial cell migration, open tracheal system=0007427 |... progression of morphogenetic furrow .. compound eye morphogenesis=0007458 | anterior head segmentation=0035288 | ectoderm development=0007398 |" plasma membrane ; GO:0005886 | inferred from direct assay endocytic vesicle ; GO:0030139 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement extracellular region ; GO:0005576 | traceable author statement endosome ; GO:0005768 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | non-traceable author statement "hh, Hh, HH, anon-WO0182946.19, Mrt, hg, bar-3, l(3)neo56, bar3, bar, l(3)hh, l(3)neo57, Mir, CG4637, anon-WO0134654.19, Hg" "IPR000320:Hedgehog, N-terminal signalling domain, IPR001657:Hedgehog protein, IPR001767:Hedgehog protein, Hint domain, IPR003586:Hint domain C-terminal, IPR003587:Hint domain N-terminal, IPR006141:Intein N-terminal splicing region, IPR009045:Hedgehog signalling/DD-peptidase zinc-binding domain, IPR028992:Hedgehog/Intein (Hint) domain" CG4637 11-Aug-17 DroID_v2017_08 "Drer\ihhb, Drer\shhb, Drer\dhh, Drer\shha, Drer\ihha" - "Cele\wrt-1, Cele\grd-14, Cele\hog-1, Cele\grd-4, Cele\grd-2, Cele\grd-11, Cele\wrt-6, Cele\wrt-9, Cele\wrt-4, Cele\wrt-8, Cele\wrt-7, Cele\qua-1, Cele\grd-13, Cele\wrt-2" "Xtro\dhh, Xtro\shh, Xtro\ihh" "Mmus\Shh, Mmus\Dhh, Mmus\Ihh" "Hsap\SHH, Hsap\IHH, Hsap\DHH" " embryonic stage , embryonic stage | stage 5 , embryonic stage | cellular blastoderm , embryonic stage | extended germ band , embryonic stage | stage >=5 , embryonic stage | mid , embryonic stage | stage >5 , embryonic stage | stage >=6 , larval stage " " embryonic/larval esophagus

, proctodeum

, embryonic/larval pharynx

, organism | 60-70% egg length

, antennal segment

, maxillary segment

, embryonic/larval foregut

,

segment polarity{ $ nkd* } ,

segment polarity , procephalic segment

, embryonic/larval salivary gland

, organism | 10% egg length

,

10-70% egg length | stripes , intercalary segment

, labial segment

, anal pad

, embryonic/larval hindgut | presumptive

, parasegment 2,4,6,8,10,12,14

{ v wg* } , organism | 90% egg length

, mandibular segment

, embryonic/larval hindgut

, embryonic/larval posterior spiracle

, antennal lobe

, dorsal mesothoracic disc | posterior

, embryonic/larval anterior spiracle

, procephalic segment

{ - ftz- } , labral segment

,

segment polarity{ $ eve* } ,

segment polarity{ $ patch* } " larval stage | third instar stage 2 eye-antennal disc

restricted "lethal,heat sensitive,visible,partially lethal - majority die,dominant,wild-type,recessive,segment polarity phenotype,somatic clone,semidominant,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,paternal effect,cold sensitive,lethal - all die before end of pupal stage,some die during pupal stage,planar polarity defective,mitotic cell cycle defective,cell migration defective,neuroanatomy defective,increased cell death,increased cell number,size defective" "germarium,egg chamber,germarium region 2a,germarium region 2b,germarium region 3,follicle cell,anterior scutellar bristle,posterior scutellar bristle,,dorsal thick hair,embryonic/first instar larval cuticle,wing,scutellar bristle,trichogen cell,ventral nerve cord commissure,eye,eye disc,male genitalia,anal plate,genital arch,male terminalia sensillum,penis,hypandrial process,basal apodeme of penis,gonopod thorn bristle,gonopod long bristle,ovariole,ommatidium,embryonic/larval epidermis,ommatidial precursor cluster,neuroblast,embryonic head,denticle,embryonic gnathal segment,wing vein,embryonic epidermis,pseudotrachea,cuticle,embryo,ventral double row,dorsal double row,dorsal triple row,medial triple row,ventral triple row,macrochaeta,prescutum,scutum,scutellum,fronto-orbital plate,frons,interfollicle cell,polar follicle cell,oocyte nucleus,oocyte,basal stalk,tergite,leg,ejaculatory bulb apodeme,eye equator,epidermis,embryonic head epidermis,embryonic brain,embryonic optic lobe,adult eye primordium,cardial valve,proventriculus outer layer,embryonic/larval foregut,abdominal ventral transverse muscle 1 founder cell,abdominal lateral oblique muscle 1 founder cell,embryonic hindgut,embryonic rectum,embryonic small intestine,embryonic large intestine,embryonic/larval fat body,Bolwig organ,embryonic/larval posterior spiracle,head capsule,embryonic/larval dorsal vessel,abdominal ventral denticle belt,fusome,spectrosome,sternite,oenocyte,muscle attachment site,cephalopharyngeal skeleton,wing margin,wing disc,haltere,antenna,pole cell,tracheal system,imaginal disc,morphogenetic furrow,germline cell,2nd posterior cell,embryonic dorsal epidermis,gastric caecum primordium,genital disc primordium,gonadal sheath proper primordium,fat body/gonad primordium,midline glial cell,presumptive embryonic/larval central nervous system,commissure,mesothoracic tarsal bristle longitudinal row,lamina,embryonic/larval optic stalk,glial cell,1st posterior cell,lamina tangential neuron,lamina intrinsic neuron,unguis,prothoracic leg disc,genital disc,follicle stem cell,ventral thoracic disc,peripodial epithelium,dorsal fine hair,ocellus,ocellar bristle,postvertical bristle,interocellar bristle,embryonic segment,subretinal glial cell,lamina anlage glial cell,eye-antennal disc,abdominal sternite bristle,lateral ocellus,medial ocellus,ventral multidendritic neuron vdaB,ventral midline,visceral mesoderm,abdominal tracheal pit,metathoracic tracheal pit,embryonic/larval tracheal system,embryonic/larval dorsal branch,embryonic/larval visceral branch,embryonic/larval dorsal trunk,lateral trunk anterior branch,ectoderm,cardioblast,antennal sense organ,gonad,anterior crossvein,embryonic ventral epidermis,embryonic/larval cuticle,female genital disc,male genital disc,female genitalia,C-734,sensory mother cell,en-e16E,dorsal double row | pharate adult stage,ventral double row | pharate adult stage,dorsal triple row | pharate adult stage,medial triple row | pharate adult stage,ventral triple row | pharate adult stage,wing | pharate adult stage,embryonic abdomen,germline cell |,chemosensory ventral triple row bristle,mechanosensory ventral triple row bristle,MP1 neuron,VUM neuron,lateral trunk posterior branch,prd.RG1,interommatidial bristle,retina,anterior commissure,wing disc anterior compartment |,tracheal tip cell,embryonic/larval ganglionic branch,costal cell,mesothoracic tergum,wing blade" FBgn0001476 l(1)9Fb lethal (1) 9Fb http://flybase.org/reports/FBgn0001476 - gene - - - l(1)9Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260398 Pbp49 PSEA-binding protein 49kD http://flybase.org/reports/FBgn0260398 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Pbp95 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay bent DNA binding ; GO:0003681 | inferred from direct assay snRNA transcription from RNA polymerase II promoter ; GO:0042795 | inferred from direct assay protein-DNA complex assembly ; GO:0065004 | inferred from direct assay snRNA transcription from RNA polymerase III promoter ; GO:0042796 | inferred from direct assay snRNA-activating protein complex ; GO:0019185 | inferred from physical interaction with Pbp95 snRNA-activating protein complex ; GO:0019185 | inferred from direct assay "CG42515, Pbp49, DmSNAP50, DMPBP49, CG11508, DmPBP, Dromel_CG11508_FBtr0088817_mORF, DmPBP49, DmSNAPc" "IPR022042:snRNA-activating protein complex, subunit 3" CG42515 11-Aug-17 DroID_v2017_08 Drer\snapc3 - "Cele\Y48G1BL.8, Cele\snpc-3.4, Cele\snpc-3.1, Cele\snpc-3.2, Cele\snpc-3.3" Xtro\snapc3 Mmus\Snapc3 Hsap\SNAPC3 FBgn0036178 CG14137 - http://flybase.org/reports/FBgn0036178 protein_coding_gene - - - CG14137 - CG14137 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0262741 MRE23 mRNA-like ncRNA in embryogenesis 23 http://flybase.org/reports/FBgn0262741 non_protein_coding_gene - - - "MRE23, CR43126" - CR43126 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060500 l(3)S106713 lethal (3) S106713 http://flybase.org/reports/FBgn0060500 gene - - - "1067/13, l(3)S106713" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0003325 Scotched-eye Scotched eye http://flybase.org/reports/FBgn0003325 - gene - - - "Sc, Scotched-eye" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female,female fertile,lethal,recessive,visible,dominant,reduced" "ommatidium,eye,abdomen,female" FBgn0005327 Pale Pale http://flybase.org/reports/FBgn0005327 - gene - - - "Pale, P" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038395 CG10407 - http://flybase.org/reports/FBgn0038395 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CG10407, cg10407" IPR010562:Haemolymph juvenile hormone binding CG10407 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031736 CG11030 - http://flybase.org/reports/FBgn0031736 protein_coding_gene - "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000326128" nucleoplasm ; GO:0005654 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000326128 CG11030 IPR007146:Sas10/Utp3/C1D CG11030 11-Aug-17 DroID_v2017_08 Drer\ngdn Scer\LCP5 Cele\lpd-2 Xtro\ngdn Mmus\Ngdn Hsap\NGDN "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02120 EK 1.380869704 1.33356492 2.119776056 -1.432372991 1.603420862 0.773291202 FBgn0002760 mit(1)10 mitotic 10 http://flybase.org/reports/FBgn0002760 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0044091 E(rst)D25 E(rst)D25 http://flybase.org/reports/FBgn0044091 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D25, E(rst)D25" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021931 l(2)k11021 lethal (2) k11021 http://flybase.org/reports/FBgn0021931 - gene - - - l(2)k11021 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085530 CG40871 - http://flybase.org/reports/FBgn0085530 protein_coding_gene - - - CG40871 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267187 CR45627 - http://flybase.org/reports/FBgn0267187 non_protein_coding_gene - - - CR45627 - CR45627 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036056 CG6709 - http://flybase.org/reports/FBgn0036056 protein_coding_gene - - - CG6709 IPR011992:EF-hand domain pair CG6709 11-Aug-17 DroID_v2017_08 - - Cele\tppp-1 - - "Hsap\TPPP2, Hsap\TPPP3, Hsap\TPPP" "viable,fertile" FBgn0028228 l(3)S005028 lethal (3) S005028 http://flybase.org/reports/FBgn0028228 gene - - - "l(3)S005028, l(3)S127405" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013586 l(3)97Da lethal (3) 97Da http://flybase.org/reports/FBgn0013586 - gene - - - l(3)97Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0037611 CG11755 - http://flybase.org/reports/FBgn0037611 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11755 "IPR018785:Cysteine-rich domain, DPF-motif" CG11755 11-Aug-17 DroID_v2017_08 Drer\si:ch211-239e6.4 - Cele\D2089.3 - Mmus\Cdpf1 Hsap\CDPF1 viable FBgn0037228 CG1092 - http://flybase.org/reports/FBgn0037228 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG1092 - CG1092 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0027149 l(3)71CDa lethal (3) 71CDa http://flybase.org/reports/FBgn0027149 - gene - - - l(3)71CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044105 E(rst)C41 E(rst)C41 http://flybase.org/reports/FBgn0044105 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C41, E(rst)C41" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "eye,cone cell" FBgn0011206 bol boule http://flybase.org/reports/FBgn0011206 "FBgn0040826, FBgn0063736" protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA binding ; GO:0003723 | inferred from mutant phenotype meiotic G2/MI transition ; GO:0008315 | traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype meiotic G2/MI transition ; GO:0008315 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype regulation of translation ; GO:0006417 | inferred from genetic interaction with twe spermatocyte division ; GO:0048137 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay perikaryon ; GO:0043204 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "bol, CG4727, Boule, CG4760, BcDNA:AT13332, ms(3)07272, BOL, Bol, lincRNA.485" IPR000504:RNA recognition motif domain CG4760 11-Aug-17 DroID_v2017_08 "Drer\zcrb1, Drer\dazl, Drer\hnrnpa1b, Drer\rbm34, Drer\hnrnpd, Drer\eif4h, Drer\raly, Drer\cirbpa, Drer\hnrnpaba, Drer\eif4ba, Drer\zgc:55733, Drer\trnau1apb, Drer\hnrnpabb, Drer\hnrnpc, Drer\srsf10a, Drer\trnau1apa, Drer\ncoa5, Drer\wu:fq32h04, Drer\hnrnpa3" "Scer\NOP6, Scer\CWC2, Scer\NGR1, Scer\NAB6, Scer\MUD1, Scer\NOP12, Scer\MRN1, Scer\NAM8" "Cele\daz-1, Cele\fox-1" "Xtro\cirbp, Xtro\hnrnpc, Xtro\hnrnpdl, Xtro\dazl, Xtro\rbm34, Xtro\hnrnpa3, Xtro\eif4h, Xtro\eif4b, Xtro\trnau1ap, Xtro\hnrnpab, Xtro\hnrnpd, Xtro\hnrnpa1, Xtro\raly, Xtro\ralyl, Xtro\hnrnpa2b1" "Mmus\Srsf10, Mmus\Eif4b, Mmus\Zcrb1, Mmus\Raly, Mmus\Hnrnpab, Mmus\Rbm34, Mmus\Cirbp, Mmus\Hnrnpa3, Mmus\Trnau1ap, Mmus\Tra2b, Mmus\Gm21379, Mmus\Hnrnpa2b1, Mmus\Srsf12, Mmus\Eif4h, Mmus\Hnrnpc, Mmus\Slirp, Mmus\Hnrnpa1, Mmus\Hnrnpd, Mmus\Boll, Mmus\Rbm31y, Mmus\Dazl" "Hsap\SRSF10, Hsap\HNRNPCL1, Hsap\CIRBP, Hsap\RALY, Hsap\SLIRP, Hsap\RALYL, Hsap\TRNAU1AP, Hsap\HNRNPA2B1, Hsap\EIF4H, Hsap\EIF4B, Hsap\DAZ2, Hsap\DAZ3, Hsap\HNRNPC, Hsap\DAZ1, Hsap\HNRNPAB, Hsap\HNRNPD, Hsap\DAZL, Hsap\RBM38, Hsap\HNRNPA1L2, Hsap\BOLL, Hsap\HNRNPA3, Hsap\DAZ4, Hsap\HNRNPA1, Hsap\RBM34, Hsap\RBM3" " spermatogenesis && adult stage , larval stage&&pupal stage " testis

"meiotic cell cycle defective,male,male sterile,recessive,viable,fertile,visible" "Kenyon cell | pupal stage,gamma Kenyon cell | pupal stage,spindle | male,testis,Nebenkern,primary spermatocyte cyst,germline cell,male,eye,wing,posterior compartment,spermatozoon,spermatid,chaeta" FBgn0053547 Rim Rab3 interacting molecule http://flybase.org/reports/FBgn0053547 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from electronic annotation with InterPro:IPR010911 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR010911 calcium ion regulated exocytosis ; GO:0017156 | inferred from sequence or structural similarity with UniProtKB:Q9JIR3 synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype regulation of synaptic plasticity ; GO:0048167 | inferred from mutant phenotype clustering of voltage-gated calcium channels ; GO:0070073 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement synaptic vesicle ; GO:0008021 | non-traceable author statement presynaptic active zone ; GO:0048786 | inferred from direct assay "CG33547, UNC-10/RIM, CG7301, CG7321, RIM, CG7305, Rim, dm-Rim, DmRIM, rim" "IPR000008:C2 domain, IPR001478:PDZ domain, IPR010911:Rab-binding domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR017455:Zinc finger, FYVE-related, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG33547 11-Aug-17 DroID_v2017_08 "Drer\rims4, Drer\zmp:0000001274, Drer\LOC568486, Drer\rims3, Drer\rims1b, Drer\rims2b, Drer\rims2a" - "Cele\tag-80, Cele\unc-10" "Xtro\rims3, Xtro\rims1, Xtro\rims2" "Mmus\Rims2, Mmus\Rims4, Mmus\Rims1, Mmus\Rims3, Mmus\Pclo" "Hsap\RIMS4, Hsap\PCLO, Hsap\RIMS2, Hsap\RIMS3, Hsap\RIMS1" "viable,fertile,neurophysiology defective" DRSC16227 I -1.693069091 0.274729917 -0.226377861 0.514883545 0.369804269 -0.793992979 FBgn0030697 CG8565 - http://flybase.org/reports/FBgn0030697 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:11306 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000622883" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:11306 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 regulation of mRNA processing ; GO:0050684 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 protein phosphorylation ; GO:0006468 | non-traceable author statement spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:11306 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:11306 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 "SPRK2, CG8565" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG8565 11-Aug-17 DroID_v2017_08 "Drer\srpk1a, Drer\srpk1b, Drer\srpk2, Drer\srpk3, Drer\si:ch211-220i18.4" Scer\SKY1 Cele\spk-1 "Xtro\srpk1, Xtro\srpk2, Xtro\srpk3, Xtro\LOC100144966" "Mmus\Srpk3, Mmus\Srpk2, Mmus\Srpk1" "Hsap\SRPK3, Hsap\SRPK2, Hsap\SRPK1" FBgn0052828 CG32828 - http://flybase.org/reports/FBgn0052828 protein_coding_gene - - - CG32828 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028532 CG7968 - http://flybase.org/reports/FBgn0028532 protein_coding_gene - - - "DS00941.15, BG:DS00941.15, CG7968" IPR010562:Haemolymph juvenile hormone binding CG7968 11-Aug-17 DroID_v2017_08 - - Cele\fbxa-14 - - - viable FBgn0060449 l(3)S120710 lethal (3) S120710 http://flybase.org/reports/FBgn0060449 gene - - - "1207/10, l(3)S120710" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265880 CR44669 - http://flybase.org/reports/FBgn0265880 non_protein_coding_gene - - - "CR44669, lincRNA.597" - CR44669 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265858 CR44647 - http://flybase.org/reports/FBgn0265858 non_protein_coding_gene - - - CR44647 - CR44647 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014906 Hydr2 alpha/beta hydrolase2 http://flybase.org/reports/FBgn0014906 - protein_coding_gene acylglycerol lipase activity ; GO:0047372 | inferred from biological aspect of ancestor with PANTHER:PTN000846580 lipase activity ; GO:0016298 | inferred from mutant phenotype steroid hormone mediated signaling pathway ; GO:0043401 | inferred from biological aspect of ancestor with PANTHER:PTN000846580 sperm capacitation ; GO:0048240 | inferred from biological aspect of ancestor with PANTHER:PTN000846580 lipid metabolic process ; GO:0006629 | inferred from mutant phenotype acylglycerol catabolic process ; GO:0046464 | inferred from biological aspect of ancestor with PANTHER:PTN000846580 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx chaeta development ; GO:0022416 | inferred from genetic interaction with Chi sperm flagellum ; GO:0036126 | inferred from biological aspect of ancestor with PANTHER:PTN000846580 sperm plasma membrane ; GO:0097524 | inferred from biological aspect of ancestor with PANTHER:PTN000846580 "CT11757, anon-23Da, DMU29170, anon-23D, c24, C24, cg3488, HYDR2, Hydr2, CG3488" "IPR000952:AB hydrolase 4, conserved site, IPR012020:AB hydrolase 4 family, IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG3488 11-Aug-17 DroID_v2017_08 "Drer\abhd2b, Drer\abhd3, Drer\abhd2a" "Scer\EHT1, Scer\YMR210W, Scer\EEB1" - "Xtro\abhd2, Xtro\abhd3" "Mmus\Abhd3, Mmus\Abhd15, Mmus\Abhd2" "Hsap\ABHD3, Hsap\ABHD1, Hsap\ABHD2" viable FBgn0260301 GSd207 - http://flybase.org/reports/FBgn0260301 gene - - - GSd207 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037788 CG3940 - http://flybase.org/reports/FBgn0037788 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from electronic annotation with InterPro:IPR018338 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR018338 - CG3940 "IPR001148:Alpha carbonic anhydrase, IPR018338:Carbonic anhydrase, alpha-class, conserved site, IPR023561:Carbonic anhydrase, alpha-class" CG3940 11-Aug-17 DroID_v2017_08 "Drer\ca10b, Drer\ca16b, Drer\cahz, Drer\ca12, Drer\ca7, Drer\ca15c, Drer\car15, Drer\ptprga, Drer\ca4b, Drer\ca2, Drer\ca4a, Drer\ca9, Drer\ca10a, Drer\ca15b, Drer\ca14, Drer\ca5a, Drer\ca6, Drer\ca8, Drer\zgc:153760, Drer\si:ch211-173d10.4, Drer\ca4c, Drer\ca15a" - "Cele\cah-6, Cele\cah-2, Cele\cah-3, Cele\cah-1, Cele\cah-4, Cele\cah-5" "Xtro\ca3, Xtro\LOC779564, Xtro\ca2, Xtro\ca7, Xtro\ca10, Xtro\ca12, Xtro\ca1, Xtro\ca8, Xtro\ca4, Xtro\ca6, Xtro\ca5b, Xtro\ca14, Xtro\ca11" "Mmus\Car14, Mmus\Car15, Mmus\Car8, Mmus\Car5a, Mmus\Car10, Mmus\Car13, Mmus\Car12, Mmus\Car6, Mmus\Car1, Mmus\Car7, Mmus\Car4, Mmus\Car9, Mmus\Car11, Mmus\Car2, Mmus\Car3, Mmus\Ptprg, Mmus\Car5b" "Hsap\CA2, Hsap\CA5B, Hsap\CA4, Hsap\CA1, Hsap\CA5A, Hsap\CA11, Hsap\CA10, Hsap\CA13, Hsap\PTPRG, Hsap\CA9, Hsap\CA14, Hsap\CA8, Hsap\CA12, Hsap\CA6, Hsap\CA7, Hsap\CA3" "viable,fertile" FBgn0264962 Pcf11 Protein 1 of cleavage and polyadenylation factor 1 http://flybase.org/reports/FBgn0264962 protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000408520 mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000408520 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA cleavage ; GO:0006379 | inferred from biological aspect of ancestor with PANTHER:PTN000408520 mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000408520 termination of RNA polymerase II transcription ; GO:0006369 | inferred from biological aspect of ancestor with PANTHER:PTN000408520 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000408520 mRNA cleavage factor complex ; GO:0005849 | inferred from biological aspect of ancestor with PANTHER:PTN000408520 "Pcf11, dPcf11, l(2)k08015, CG10228, anon-WO0118547.146, pcf11, Inr-a" "IPR006569:CID domain, IPR008942:ENTH/VHS, IPR006903:RNA polymerase II-binding domain" CG10228 11-Aug-17 DroID_v2017_08 Drer\pcf11 Scer\PCF11 Cele\pcf-11 Xtro\pcf11 Mmus\Pcf11 Hsap\PCF11 FBgn0032495 CG16820 - http://flybase.org/reports/FBgn0032495 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CG16820, cg16820" IPR010562:Haemolymph juvenile hormone binding CG16820 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,tormogen cell" FBgn0264399 FCG-A - http://flybase.org/reports/FBgn0264399 gene - - - FCG-A - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0033075 Pld Phospholipase D http://flybase.org/reports/FBgn0033075 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 phospholipase D activity ; GO:0004630 | inferred from direct assay inositol lipid-mediated signaling ; GO:0048017 | inferred from electronic annotation with InterPro:IPR016555 phosphatidic acid biosynthetic process ; GO:0006654 | inferred from electronic annotation with InterPro:IPR016555 cellularization ; GO:0007349 | inferred from mutant phenotype gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype positive regulation of Golgi vesicle fusion to target membrane ; GO:0048215 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype cytoplasmic vesicle ; GO:0031410 | inferred from direct assay "dPLD, CG12110, Pld, dPld, PLD, pld, pld1" "IPR025202:Phospholipase D-like domain, IPR001683:Phox homologous domain, IPR001736:Phospholipase D/Transphosphatidylase, IPR011993:PH domain-like, IPR015679:Phospholipase D family, IPR016555:Phospholipase D1/D2" CG12110 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-168k14.2, Drer\pld1a, Drer\pld1b, Drer\pld2" Scer\SPO14 Cele\pld-1 "Xtro\pld1, Xtro\pld2" "Mmus\Pld1, Mmus\Pld2" "Hsap\PLD1, Hsap\PLD2" "viable,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,maternal effect,developmental rate defective,neurophysiology defective" "eye photoreceptor cell,rhabdomereGMR.PF,retina,rhabdomereninaE.PD,ommatidium,gastrula embryo,blastoderm embryo,pre-blastoderm embryo,Golgi-associated vesicle" FBgn0067730 l(3)F6 lethal (3) F6 http://flybase.org/reports/FBgn0067730 gene - - - l(3)F6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265366 CR44307 - http://flybase.org/reports/FBgn0265366 non_protein_coding_gene - - - CR44307 - CR44307 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011801 l(3)rL061 lethal (3) rL061 http://flybase.org/reports/FBgn0011801 - gene - - - l(3)rL061 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0053970 CG33970 - http://flybase.org/reports/FBgn0053970 protein_coding_gene "ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871" transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR000412 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000412, InterPro:IPR013525" "CG14559, CG6162, CG6166, CG31085, CG33970" "IPR000412:ABC-2 transporter, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR013525:ABC-2 type transporter" CG33970 11-Aug-17 DroID_v2017_08 "Drer\abca1a, Drer\abca12, Drer\abca1b, Drer\abch1, Drer\abca5, Drer\abca3b, Drer\abca2" Scer\CAF16 "Cele\abt-6, Cele\Y6E2A.1" "Xtro\abca10, Xtro\abcg2, Xtro\abca3, Xtro\abca8, Xtro\abca4, Xtro\abca1, Xtro\abca9, Xtro\abca2" "Mmus\Abca17, Mmus\Abca5, Mmus\Abca6, Mmus\Abca3, Mmus\Abca7, Mmus\Abca14, Mmus\Abca9, Mmus\Abca16, Mmus\Abca2, Mmus\Abca4, Mmus\Abca8a, Mmus\Abca8b, Mmus\Abca1, Mmus\Abca13, Mmus\Abca12, Mmus\Abca15" "Hsap\ABCA2, Hsap\ABCA8, Hsap\ABCA10, Hsap\ABCA4, Hsap\ABCA12, Hsap\ABCG2, Hsap\ABCA7, Hsap\ABCA6, Hsap\ABCA9, Hsap\ABCA5, Hsap\ABCA1, Hsap\ABCA3, Hsap\ABCA13" lethal FBgn0044014 Smac49a Smac49a http://flybase.org/reports/FBgn0044014 gene - - - Smac49a - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038190 CG9926 - http://flybase.org/reports/FBgn0038190 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9926 IPR000313:PWWP domain CG9926 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-116m6.3, Drer\hdgfrp3, Drer\psip1, Drer\hdgfrp2, Drer\rogdi" "Scer\PDP3, Scer\IOC4" Cele\C06A5.3 "Xtro\glyr1, Xtro\hdgfrp2, Xtro\psip1" "Mmus\Hdgf, Mmus\Glyr1, Mmus\Hdgfrp3, Mmus\Hdgfl1, Mmus\Hdgfrp2, Mmus\Psip1" "Hsap\PSIP1, Hsap\GLYR1, Hsap\HDGFRP3, Hsap\HDGFL1, Hsap\HDGFRP2, Hsap\HDGF" FBgn0265205 CR44265 - http://flybase.org/reports/FBgn0265205 non_protein_coding_gene - - - CR44265 - CR44265 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010374 uni unicorn http://flybase.org/reports/FBgn0010374 - gene - - - uni - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male fertile" FBgn0051111 CG31111 - http://flybase.org/reports/FBgn0051111 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR003888, InterPro:IPR003889" "CG13649, CG31111" "IPR003888:FY-rich, N-terminal, IPR003889:FY-rich, C-terminal" CG31111 11-Aug-17 DroID_v2017_08 Drer\tbrg1 - - Xtro\tbrg1 Mmus\Tbrg1 Hsap\TBRG1 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC14649 I -1.504314781 -0.39908959 0.737323531 -1.198998126 1.13947958 0.200354411 FBgn0052642 CG32642 - http://flybase.org/reports/FBgn0052642 protein_coding_gene - chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern chorion ; GO:0042600 | inferred by curator from GO:0007304 CG32642 IPR012334:Pectin lyase fold CG32642 11-Aug-17 DroID_v2017_08 - - "Cele\jud-4, Cele\ora-1, Cele\F57H12.6, Cele\K07D4.6, Cele\F40E10.5" - - - FBgn0003514 sqh spaghetti squash http://flybase.org/reports/FBgn0003514 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 myosin heavy chain binding ; GO:0032036 | inferred from physical interaction with zip "mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | traceable author statement tube formation ; GO:0035148 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype nuclear axial expansion ; GO:0035191 | inferred from mutant phenotype apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype cell elongation involved in imaginal disc-derived wing morphogenesis ; GO:0090254 | inferred from mutant phenotype actin filament-based movement ; GO:0030048 | inferred by curator from GO:0016460 mitotic cytokinesis ; GO:0000281 | inferred from direct assay establishment of planar polarity ; GO:0001736 | non-traceable author statement formation of a compartment boundary ; GO:0060288 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement wound healing ; GO:0042060 | inferred from mutant phenotype myosin II filament assembly ; GO:0031036 | inferred from mutant phenotype cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte ; GO:0019749 | inferred from mutant phenotype regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with fz border follicle cell migration ; GO:0007298 | inferred from mutant phenotype" cleavage furrow ; GO:0032154 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay cell-cell junction ; GO:0005911 | colocalizes_with inferred from direct assay myosin II complex ; GO:0016460 | inferred from physical interaction with zip spindle midzone ; GO:0051233 | inferred from direct assay female germline ring canal inner rim ; GO:0035183 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay "sqh, Myo-II, NMM, myoII, MRLC, RLC, CG3595, DmMRLC_C, Sqh, spg, ssq, sgh, Myo II, MyoII, Myo-II RLC, Myo, RMLC, MLC, squ, MLRC, myosin II, myo II, myosin, RLC2" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG3595 11-Aug-17 DroID_v2017_08 "Drer\myl7, Drer\mylpfa, Drer\myl12.1, Drer\myl2a, Drer\myl2b, Drer\myl12.2, Drer\myl9b, Drer\myl9a, Drer\mylpfb, Drer\myl10" Scer\MLC2 "Cele\mlc-2, Cele\mlc-4, Cele\mlc-1" "Xtro\myl2, Xtro\myl12b, Xtro\myl9, Xtro\myl7, Xtro\mylpf, Xtro\myl10" "Mmus\Myl2, Mmus\Myl12b, Mmus\Myl10, Mmus\Mylpf, Mmus\Myl7, Mmus\Myl9, Mmus\Myl12a" "Hsap\MYL5, Hsap\MYL9, Hsap\MYL7, Hsap\MYL2, Hsap\MYL12B, Hsap\MYL10, Hsap\MYLPF, Hsap\MYL12A" "short lived,calorie restriction conditional,cytokinesis defective,wound healing defective,recessive,cell migration defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,maternal effect,partially lethal - majority die,wild-type,neuroanatomy defective,somatic clone,cell shape defective,axis specification defective,male limited,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective" "eye disc,somatic clone,wing disc | third instar larval stage,wing disc,somatic clone | third instar larval stage,furrow canal,posterior,nucleus | embryonic stage 4,oocyte,germline clone,nurse cell,egg,posterior spiracle primordium,morphogenetic furrow,organism | embryonic stage,embryo,eye,leg,distal,embryonic segment,ventral thoracic disc,wing,ovary,border follicle cell,centripetally migrating follicle cell,dorsal appendage,interfollicle cell,actomyosin contractile ring,mitotic telophase,mitotic telophase & spindle,egg chamber,nurse cell ring canal,extended germ band embryo,epidermis,hub cell,embryonic/larval dorsal trunk,epithelium,follicle cell,anterior embryonic/larval midgut,male limited,embryonic proventriculus,adult brain,mitochondrion,adult mushroom body,cystocyte,cephalopharyngeal skeleton,denticle belt,S2 cell-line & spindle microtubule,S2 cell-line & cell,S2 cell-line & spindle,embryonic/larval neuroblast,ganglion mother cell" FBgn0061495 l(2)45As lethal (2) 45As http://flybase.org/reports/FBgn0061495 gene - - - l(2)45As - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014366 noi noisette http://flybase.org/reports/FBgn0014366 FBgn0011357 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000690 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000300247 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:10767 "fertilization ; GO:0009566 | inferred from mutant phenotype positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002188 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of cell cycle ; GO:0051726 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000300247" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000002188 "CG2925, SF3a[60], ms3225, l(3)j3E7, U2, noi, Noi, SF3A3" "IPR000690:Matrin/U1-C, C2H2-type zinc finger, IPR024598:Domain of unknown function DUF3449, IPR021966:Splicing factor SF3a60 binding domain, IPR031776:Splicing factor 3A subunit 3, IPR031774:SF3A3 domain" CG2925 11-Aug-17 DroID_v2017_08 Drer\sf3a3 Scer\PRP9 Cele\T13H5.4 Xtro\sf3a3 Mmus\Sf3a3 Hsap\SF3A3 "lethal,recessive,male sterile,viable,male,female,female sterile,cold sensitive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type" "germline cell,male,nurse cell,nurse cell & nucleus,oocyte nucleus,dorsal appendage,egg,head & macrochaeta | dorsal,thorax & macrochaeta | dorsal,sex comb,medial triple row" DRSC12383 IK 1.715278791 1.043307159 -0.391640131 -1.024353493 -1.749097176 -0.448378309 FBgn0039679 ppk19 pickpocket 19 http://flybase.org/reports/FBgn0039679 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 "response to salt stress ; GO:0009651 | inferred from mutant phenotype salt aversion ; GO:0035199 | inferred from mutant phenotype sensory perception of salty taste ; GO:0050914 | inferred from mutant phenotype liquid clearance, open tracheal system ; GO:0035002 | non-traceable author statement sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK19, CG18287, ppk19" IPR001873:Epithelial sodium channel CG18287 11-Aug-17 DroID_v2017_08 "Drer\asic2, Drer\asic1b, Drer\asic4b, Drer\asic1a, Drer\asic1c, Drer\asic4a" - "Cele\acd-2, Cele\del-7, Cele\acd-1, Cele\acd-4, Cele\delm-1, Cele\acd-5, Cele\acd-3, Cele\flr-1, Cele\delm-2, Cele\unc-8" "Xtro\scnn1g, Xtro\scnn1d, Xtro\asic1, Xtro\asic5, Xtro\scnn1a, Xtro\asic4, Xtro\scnn1b" "Mmus\Asic4, Mmus\Asic5, Mmus\Scnn1g, Mmus\Scnn1b, Mmus\Scnn1a, Mmus\Asic2, Mmus\Asic3, Mmus\Asic1" "Hsap\SCNN1D, Hsap\SCNN1A, Hsap\ASIC4, Hsap\SCNN1G, Hsap\ASIC2, Hsap\SCNN1B, Hsap\ASIC5, Hsap\ASIC1, Hsap\ASIC3" "taste perception defective,viable" FBgn0266311 CR44976 - http://flybase.org/reports/FBgn0266311 non_protein_coding_gene - - - CR44976 - CR44976 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052037 CG32037 - http://flybase.org/reports/FBgn0052037 protein_coding_gene - - - "CG3426, CG32037" - CG32037 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040811 CG13479 - http://flybase.org/reports/FBgn0040811 protein_coding_gene - - - CG13479 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028479 Mtpalpha Mitochondrial trifunctional protein alpha subunit http://flybase.org/reports/FBgn0028479 protein_coding_gene long-chain-3-hydroxyacyl-CoA dehydrogenase activity ; GO:0016509 | inferred from sequence or structural similarity with UniProtKB:P40939 enoyl-CoA hydratase activity ; GO:0004300 | inferred from sequence or structural similarity with UniProtKB:Q64428 long-chain-3-hydroxyacyl-CoA dehydrogenase activity ; GO:0016509 | inferred from sequence or structural similarity with UniProtKB:Q64428 fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with UniProtKB:P40939 fatty acid beta-oxidation ; GO:0006635 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with UniProtKB:Q64428 response to starvation ; GO:0042594 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:3247 inferred from sequence model inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial fatty acid beta-oxidation multienzyme complex ; GO:0016507 | inferred from sequence or structural similarity with UniProtKB:P40939 mitochondrion ; GO:0005739 | inferred from sequence model "BcDNA:GH12558, Mtpalpha, CG4389, CG 4389" "IPR001753:Crotonase superfamily, IPR006108:3-hydroxyacyl-CoA dehydrogenase, C-terminal, IPR006176:3-hydroxyacyl-CoA dehydrogenase, NAD binding, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR012803:Fatty acid oxidation complex, alpha subunit, mitochondrial, IPR018376:Enoyl-CoA hydratase/isomerase, conserved site, IPR013328:6-phosphogluconate dehydrogenase, domain 2, IPR016040:NAD(P)-binding domain, IPR029045:ClpP/crotonase-like domain" CG4389 11-Aug-17 DroID_v2017_08 "Drer\hadhaa, Drer\hadhab, Drer\ehhadh" - "Cele\ech-1.2, Cele\ech-1.1" Xtro\hadha "Mmus\Ehhadh, Mmus\Hadha" "Hsap\HADHA, Hsap\EHHADH" "viable,fertile,short lived,locomotor behavior defective,starvation stress response defective" "adult fat body,lipid particle" FBgn0003476 Spl Splayed http://flybase.org/reports/FBgn0003476 FBgn0005223 gene - - - "l(3)ET23, Spl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" "leg,joint" FBgn0020863 chianti chianti http://flybase.org/reports/FBgn0020863 - gene - - - "chi, chianti" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0016689 Oab Orientation abnormal http://flybase.org/reports/FBgn0016689 - gene molecular_function ; GO:0003674 | no biological data available eye development ; GO:0001654 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Oab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" ommatidium FBgn0084644 2.15.50 2.15.50 http://flybase.org/reports/FBgn0084644 gene - - - 2.15.50 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective" "pigment cell,eye" FBgn0022709 Adk1 Adenylate kinase 1 http://flybase.org/reports/FBgn0022709 FBgn0036265 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850, InterPro:IPR006267 adenylate kinase activity ; GO:0004017 | inferred from direct assay adenylate kinase activity ; GO:0004017 | inferred from sequence or structural similarity with SGD:S000001507 uridylate kinase activity ; GO:0009041 | inferred from sequence or structural similarity with SGD:S000001507" ATP metabolic process ; GO:0046034 | inferred from electronic annotation with InterPro:IPR006267 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from sequence or structural similarity with SGD:S000001507 nucleobase-containing compound metabolic process ; GO:0006139 | inferred from sequence or structural similarity with SGD:S000001507 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000001507 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000001507 "DAK1, bs34e10.y1, AK1, ADK-1, CG17146, Adk1, adk1, Dak1" "IPR000850:Adenylate kinase/UMP-CMP kinase, IPR006267:Adenylate kinase, isozyme 1/5, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033690:Adenylate kinase, conserved site" CG17146 11-Aug-17 DroID_v2017_08 "Drer\cmpk, Drer\si:ch211-199m3.4, Drer\ak1, Drer\ak5, Drer\ak5l" Scer\URA6 "Cele\F13E6.2, Cele\C29F7.3, Cele\F40F8.1, Cele\F38B2.4" "Xtro\ak1, Xtro\cmpk1" "Mmus\Ak9, Mmus\Ak1, Mmus\Cmpk1, Mmus\Ak5, Mmus\Ak8" "Hsap\AK5, Hsap\LOC390877, Hsap\AK9, Hsap\AK1, Hsap\CMPK1" viable FBgn0017403 eddy eddy http://flybase.org/reports/FBgn0017403 - gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available eddy - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile,male fertile" "photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina anlage,precursor" FBgn0041836 Eth-AR209 Eth-AR209 http://flybase.org/reports/FBgn0041836 gene - - - "Eth[AR]209, Eth-AR209" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0265534 CR44384 - http://flybase.org/reports/FBgn0265534 non_protein_coding_gene - - - CR44384 - CR44384 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267201 CR45641 - http://flybase.org/reports/FBgn0267201 non_protein_coding_gene - - - CR45641 - CR45641 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005652 Mst59Db Male-specific transcript 59Db http://flybase.org/reports/FBgn0005652 - gene - - - Mst59Db - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000078 Amy-d Amylase distal http://flybase.org/reports/FBgn0000078 FBgn0014456 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006046, InterPro:IPR006047, InterPro:IPR006048, InterPro:IPR015902 cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR006046, InterPro:IPR006047, InterPro:IPR006048, InterPro:IPR006589 calcium ion binding ; GO:0005509 | traceable author statement alpha-amylase activity ; GO:0004556 | traceable author statement" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006046, InterPro:IPR006047, InterPro:IPR006048, InterPro:IPR006589, InterPro:IPR013781 carbohydrate metabolic process ; GO:0005975 | traceable author statement" - "Amy, AMY, amy, amy-d, CG17876, Amy6, Amy3, Amy1, amyB(3), alphaAmy, AmyB, alpha-AMY, Amy-d, AmyD, Amy(d), Amy-distal" "IPR006046:Alpha amylase, IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR006048:Alpha-amylase/branching enzyme, C-terminal all beta, IPR017853:Glycoside hydrolase superfamily, IPR031319:Alpha-amylase, C-terminal domain" CG17876 11-Aug-17 DroID_v2017_08 "Drer\amy2a, Drer\zgc:66313, Drer\zgc:92137" - Cele\C50B6.7 "Xtro\amy2b, Xtro\amy2a" "Mmus\Amy2a5, Mmus\Amy2a3, Mmus\Amy2a1, Mmus\Amy2a4, Mmus\Amy2b, Mmus\Amy2a2, Mmus\Amy1" "Hsap\AMY2A, Hsap\AMY1B, Hsap\AMY1C, Hsap\AMY1A, Hsap\AMY2B" adult stage adult midgut

adult stage " midgut

{ - mapP00 } , adult midgut

, midgut

" electrophoretic variant FBgn0024240 eel eel http://flybase.org/reports/FBgn0024240 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available eel - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038252 BigH1 Histone H1 variant BigH1 http://flybase.org/reports/FBgn0038252 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR005818 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818 regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype regulation of nucleosome density ; GO:0060303 | inferred from mutant phenotype" nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR005818 chromatin ; GO:0000785 | inferred from direct assay "CG3509, BigH1, dBigH1, Big H1" "IPR005818:Linker histone H1/H5, domain H15, IPR011991:Winged helix-turn-helix DNA-binding domain" CG3509 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.10, Drer\h1m, Drer\zgc:110216, Drer\zgc:153405, Drer\histh1l, Drer\si:ch1073-159d7.7, Drer\si:dkey-108k21.21, Drer\si:ch73-36p18.1, Drer\si:ch211-113a14.24, Drer\si:dkey-261m9.12, Drer\h1fx, Drer\zgc:163061, Drer\zgc:110425, Drer\si:dkey-108k21.14" Scer\HHO1 - - "Mmus\Hist1h1d, Mmus\Hist1h1c, Mmus\Hist1h1b, Mmus\H1fx, Mmus\Hils1, Mmus\Hist1h1t, Mmus\Hist1h1e, Mmus\H1fnt, Mmus\Hist1h1a, Mmus\H1foo" "Hsap\HIST1H1C, Hsap\HIST1H1D, Hsap\HIST1H1A, Hsap\HIST1H1B, Hsap\H1FNT, Hsap\H1FX, Hsap\HIST1H1E, Hsap\HIST1H1T, Hsap\H1FOO" "lethal - all die during embryonic stage,viable" FBgn0001002 Fs(2)Tld Female sterile (2) Told http://flybase.org/reports/FBgn0001002 - gene - - - "Told, Fs(2)Sz11, Fs(2)Tld" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,dominant,female sterile soma-dependent" embryonic head FBgn0013459 fs(2)neo9 fs(2)neo9 http://flybase.net/reports/FBgn0013459.html gene unnamed 11-Aug-17 DroID_v2017_08 "female sterile,recessive,lethal,maternal effect" FBgn0000528 E81 E81 http://flybase.org/reports/FBgn0000528 - gene - - - E81 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041835 Eth-AR217 Eth-AR217 http://flybase.org/reports/FBgn0041835 gene - - - "Eth[AR]217, Eth-AR217" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0265374 CR44315 - http://flybase.org/reports/FBgn0265374 non_protein_coding_gene - - - CR44315 - CR44315 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050278 CG30278 - http://flybase.org/reports/FBgn0050278 protein_coding_gene - - - "CG3387, CG30278" - CG30278 11-Aug-17 DroID_v2017_08 "Drer\LOC101883455, Drer\slco1c1, Drer\slco5a1, Drer\slco1f3, Drer\slco3a1, Drer\slco1f4, Drer\slco4a1, Drer\LOC100536648, Drer\slco2b1, Drer\slco1f2, Drer\LOC570448" - - "Xtro\slco4c1, Xtro\slco1b3, Xtro\slco2a1, Xtro\slco4a1, Xtro\slco3a1, Xtro\slco5a1" "Mmus\Slco3a1, Mmus\Slco1a6, Mmus\Slco6d1, Mmus\Slco5a1, Mmus\Slco2b1, Mmus\Slco1a1, Mmus\Slco1c1, Mmus\Slco1b2, Mmus\Slco1a4, Mmus\Gm6614, Mmus\Slco4a1, Mmus\Slco4c1, Mmus\Slco1a5, Mmus\Slco6c1, Mmus\Gm5724, Mmus\Slco2a1" "Hsap\SLCO1B1, Hsap\SLCO4C1, Hsap\SLCO2B1, Hsap\SLCO6A1, Hsap\SLCO5A1, Hsap\SLCO4A1, Hsap\SLCO3A1, Hsap\SLCO1B3, Hsap\SLCO1B7, Hsap\SLCO1A2, Hsap\SLCO2A1, Hsap\SLCO1C1" viable DRSC22787 E -0.807424664 -0.669509457 -1.844067628 -1.256954094 -0.283834291 -1.209626107 FBgn0262880 CG43235 - http://flybase.org/reports/FBgn0262880 protein_coding_gene metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR003146 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG43235 "IPR003146:Carboxypeptidase, activation peptide, IPR009020:Protease propeptides/proteinase inhibitor I9" CG43235 11-Aug-17 DroID_v2017_08 "Drer\cpa5, Drer\cpa1, Drer\cpa2, Drer\cpb1, Drer\cpo, Drer\cpb2, Drer\cpa6, Drer\cpa4" Scer\ECM14 "Cele\W01A8.6, Cele\Y18H1A.9, Cele\Y47G6A.19, Cele\T06A4.3, Cele\suro-1, Cele\T06A4.1, Cele\ZC434.9" "Xtro\cpa1, Xtro\cpo, Xtro\cpb2, Xtro\cpb1, Xtro\cpa3" "Mmus\Cpa5, Mmus\Cpa6, Mmus\Cpa4, Mmus\Cpb1, Mmus\Cpb2, Mmus\Cpa3, Mmus\Cpa1, Mmus\Cpa2" "Hsap\CPA1, Hsap\CPO, Hsap\CPB2, Hsap\CPB1, Hsap\CPA6, Hsap\CPA2, Hsap\CPA5, Hsap\CPA4, Hsap\CPA3" FBgn0002101 l(2)57Db lethal (2) 57Db http://flybase.org/reports/FBgn0002101 - gene - - - "l(2)57CDc, l(2)57Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037679 CG8866 - http://flybase.org/reports/FBgn0037679 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:19703 protein kinase activity ; GO:0004672 | non-traceable author statement" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:19703 protein phosphorylation ; GO:0006468 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:19703 "UNC 51-like, CG8866, dULK3, ADUK" "IPR000719:Protein kinase domain, IPR007330:MIT, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG8866 11-Aug-17 DroID_v2017_08 "Drer\stk35l, Drer\si:ch211-63o20.7, Drer\pdik1l, Drer\stk35, Drer\ulk1a, Drer\ulk3, Drer\ulk1b, Drer\ulk2" Scer\ATG1 Cele\unc-51 "Xtro\ulk3, Xtro\ulk1, Xtro\pdik1l, Xtro\stk35" "Mmus\Ulk2, Mmus\Pdik1l, Mmus\Ulk1, Mmus\Ulk3, Mmus\Stk35" "Hsap\ULK2, Hsap\PDIK1L, Hsap\ULK3, Hsap\STK35, Hsap\ULK1" FBgn0058234 CG40234 - http://flybase.org/reports/FBgn0058234 protein_coding_gene - - - CG40234 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263835 CR43697 - http://flybase.org/reports/FBgn0263835 pseudogene_attribute - - - CR43697 - CR43697 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010138 l(2)DTS100 lethal (2) DTS100 http://flybase.org/reports/FBgn0010138 - gene - - - "DTS100, l(2)DTS100" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,dominant" FBgn0025517 fs(3)82CDa fs(3)82CDa http://flybase.org/reports/FBgn0025517 - gene - - - fs(3)82CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0041766 anon-d44 anon-d44 http://flybase.org/reports/FBgn0041766 gene - - - "d44, anon-d44" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005341 rlu rolled up http://flybase.org/reports/FBgn0005341 - gene - - - rlu - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" wing FBgn0016812 l(1)L13 lethal (1) L13 http://flybase.org/reports/FBgn0016812 - gene - - - "l(1)L13, L13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266837 CR45299 - http://flybase.org/reports/FBgn0266837 non_protein_coding_gene - - - CR45299 - CR45299 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014196 l(1)14Cc lethal (1) 14Cc http://flybase.org/reports/FBgn0014196 - gene - - - "l(1)14Cd, l(1)14Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,rescuable maternal effect,some die during larval stage" FBgn0000787 fs(1)C3 female sterile (1) C3 http://flybase.org/reports/FBgn0000787 - gene - - - fs(1)C3 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "chorion,dorsal appendage" FBgn0035823 eIF4E5 eukaryotic translation initiation factor 4E5 http://flybase.org/reports/FBgn0035823 protein_coding_gene RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Thor translation initiation factor activity ; GO:0003743 | inferred from genetic interaction with SGD:S000005499 eukaryotic initiation factor 4G binding ; GO:0031370 | inferred from physical interaction with eIF4G1 RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern translational initiation ; GO:0006413 | inferred from genetic interaction with SGD:S000005499 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from physical interaction with eIF4G1 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity "CG8277, CT24507, eIF4E, eIF4E5, eIF4E-5" "IPR001040:Translation Initiation factor eIF- 4e, IPR023398:Translation Initiation factor eIF- 4e-like, IPR019770:Eukaryotic translation initiation factor 4E (eIF-4E), conserved site" CG8277 11-Aug-17 DroID_v2017_08 "Drer\eif4eb, Drer\eif4e1b, Drer\sesn1, Drer\sesn2, Drer\eif4e1c, Drer\si:zfos-80g12.1, Drer\eif4ea" Scer\CDC33 "Cele\ife-1, Cele\ife-3, Cele\ife-2, Cele\ife-5" "Xtro\sesn3, Xtro\eif4e, Xtro\sesn1, Xtro\eif4e1b" "Mmus\Sesn1, Mmus\Sesn3, Mmus\Eif4e1b, Mmus\Eif4e, Mmus\Sesn2" "Hsap\SESN3, Hsap\SESN2, Hsap\EIF4E1B, Hsap\EIF4E, Hsap\SESN1" viable DRSC10975 E 0.078089297 -0.02156391 -1.654618156 -0.233629184 0.020744333 -0.798609818 FBgn0064173 l(2)T76 lethal (2) T76 http://flybase.org/reports/FBgn0064173 gene - - - l(2)T76 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267440 CR45790 - http://flybase.org/reports/FBgn0267440 non_protein_coding_gene - - - CR45790 - CR45790 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000999 Fs(2)Tar Female sterile (2) Tarhos http://flybase.org/reports/FBgn0000999 - gene - - - "Tar, Fs(2)Sz9, Fs(2)Tar" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,dominant" "embryo,cleavage nucleus" FBgn0032582 CG13258 - http://flybase.org/reports/FBgn0032582 protein_coding_gene - - - CG13258 - CG13258 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0002473 l(3)SG28 lethal (3) SG28 http://flybase.org/reports/FBgn0002473 - gene - - - "SG28, l(3)8m-12, l(3)SG28" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle,mitosis & nuclear chromosome,mitotic cell cycle" FBgn0040233 cana CENP-ana http://flybase.org/reports/FBgn0040233 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 kinetochore binding ; GO:0043515 | inferred from electronic annotation with InterPro:IPR033066 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from sequence or structural similarity with HGNC:1856 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity" attachment of mitotic spindle microtubules to kinetochore ; GO:0051315 | inferred from electronic annotation with InterPro:IPR033066 microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity metaphase/anaphase transition of mitotic cell cycle ; GO:0007091 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "CENP-ana, DmCana, CENP-E ana, CG4831, l(2)k07716, CG32955, CG33694, cana, Cenp-E, CENPana, Cana, Cenp_E, CP15516, KIF 10, KIF10" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019821:Kinesin motor domain, conserved site, IPR033066:Centromere-associated protein E" CG33694 11-Aug-17 DroID_v2017_08 "Drer\golga4, Drer\kif22, Drer\golgb1, Drer\znf185, Drer\kif19, Drer\cenpe, Drer\kif18a, Drer\si:dkey-26i13.8" "Scer\KIP3, Scer\MLP2, Scer\KIP2, Scer\MLP1, Scer\USO1" "Cele\che-10, Cele\F59A2.2, Cele\anc-1, Cele\golg-4" "Xtro\kif15, Xtro\kif19, Xtro\kif18a, Xtro\cenpe, Xtro\kif18b, Xtro\kif22" "Mmus\Cenpf, Mmus\Kif18a, Mmus\Golgb1, Mmus\Kif18b, Mmus\Golga4, Mmus\Cenpe, Mmus\Kif19a, Mmus\Kif22" "Hsap\CENPF, Hsap\KIF18B, Hsap\KIF22, Hsap\CENPE, Hsap\KIF19, Hsap\KIF18A, Hsap\GOLGA4, Hsap\GOLGB1" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0062669 EP3068 EP3068 http://flybase.org/reports/FBgn0062669 gene - - - "EP(3)3068, EP3068" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024622 meso1 meso1 http://flybase.org/reports/FBgn0024622 FBgn0024482 gene - - - "Clone1, meso1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029717 CG12684 - http://flybase.org/reports/FBgn0029717 protein_coding_gene - - - CG12684 IPR006629:LPS-induced tumour necrosis factor alpha factor CG12684 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260604 2L2921 - http://flybase.org/reports/FBgn0260604 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2921 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0013519 l(1)rp2 lethal (1) rp2 http://flybase.org/reports/FBgn0013519 - gene - - - l(1)rp2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0264548 CR43927 - http://flybase.org/reports/FBgn0264548 non_protein_coding_gene - - - CR43927 - CR43927 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000754 fs(1)A427 female sterile (1) A427 http://flybase.org/reports/FBgn0000754 - gene - - - fs(1)A427 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0266937 CR45388 - http://flybase.org/reports/FBgn0266937 non_protein_coding_gene - - - "CR45388, pri-mir-315" - CR45388 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015878 anon-48Ag anon-48Ag http://flybase.org/reports/FBgn0015878 - gene - - - "IX, anon-48Ag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267789 CR46120 - http://flybase.org/reports/FBgn0267789 non_protein_coding_gene - - - CR46120 - CR46120 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016774 anon-70Dc anon-70Dc http://flybase.org/reports/FBgn0016774 - gene - - - "gamma2, anon-70Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031373 CG15358 - http://flybase.org/reports/FBgn0031373 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - "CG15358, mdcds_4396" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG15358 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-88n24.10, Drer\selp, Drer\si:ch211-282j17.10, Drer\si:dkey-28d5.12, Drer\si:dkey-88n24.6, Drer\si:ch211-282j17.11, Drer\hbl1, Drer\si:dkey-83f18.3, Drer\si:dkey-81n2.2, Drer\zgc:162060, Drer\si:ch211-225k7.6, Drer\si:dkey-83f18.11, Drer\si:dkey-28d5.4, Drer\colec11, Drer\LOC100331140, Drer\hbl4, Drer\si:dkey-88n24.7, Drer\si:ch211-232p21.6, Drer\si:ch211-63p21.4, Drer\si:dkey-61f9.2, Drer\si:ch211-63p21.3, Drer\hbl2, Drer\LOC100000851, Drer\si:dkey-9i23.5, Drer\hbl3, Drer\si:ch211-225k7.4, Drer\si:dkey-192d15.3, Drer\si:dkey-9i23.4" - "Cele\clec-26, Cele\clec-17, Cele\clec-148, Cele\clec-7, Cele\clec-39, Cele\clec-9, Cele\clec-31, Cele\clec-38, Cele\clec-149, Cele\clec-45, Cele\clec-4" "Xtro\colec10, Xtro\clec3b" "Mmus\Mbl1, Mmus\Clec5a, Mmus\Klra9, Mmus\Sftpd, Mmus\Sftpa1, Mmus\Klra8, Mmus\Mgl2, Mmus\Asgr1, Mmus\Cd209e, Mmus\Klra10, Mmus\Clec10a, Mmus\Clec1b, Mmus\Klra6, Mmus\Klra5, Mmus\Colec12, Mmus\Cd207, Mmus\Klra17, Mmus\Mbl2, Mmus\Klra4, Mmus\Asgr2" "Hsap\COLEC10, Hsap\CLEC4M, Hsap\CLEC1B, Hsap\SFTPA2, Hsap\MBL2, Hsap\SFTPD, Hsap\COLEC11, Hsap\CD209, Hsap\CLEC7A, Hsap\SFTPA1, Hsap\MARCO" viable FBgn0069105 mus319 mutagen-sensitive 319 http://flybase.org/reports/FBgn0069105 gene - - - mus319 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0043861 pf-5 pairing failure-5 http://flybase.org/reports/FBgn0043861 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG5, pf-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033720 CG13160 - http://flybase.org/reports/FBgn0033720 protein_coding_gene - - - CG13160 IPR007484:Peptidase M28 CG13160 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\PFF1, Scer\YDR415C, Scer\APE3" "Cele\B0495.7, Cele\C44B7.11" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0262854 CG43218 - http://flybase.org/reports/FBgn0262854 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG43218, MB8.chr3L.pasa.58" IPR002557:Chitin binding domain CG43218 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\cpg-1, Cele\cpg-2, Cele\C39D10.7" - - - FBgn0002013 l(2)36Ff lethal (2) 36Ff http://flybase.org/reports/FBgn0002013 - gene - - - "l(2)E47, l(2)36Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035902 CG6683 - http://flybase.org/reports/FBgn0035902 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6683 IPR006578:MADF domain CG6683 11-Aug-17 DroID_v2017_08 "Drer\LOC100330838, Drer\zgc:152938, Drer\si:ch211-207i20.3" - "Cele\madf-10, Cele\madf-9, Cele\madf-2, Cele\madf-8, Cele\madf-3, Cele\madf-4, Cele\madf-5" - - - viable FBgn0031094 CG9578 - http://flybase.org/reports/FBgn0031094 protein_coding_gene molecular_function ; GO:0003674 | no biological data available DNA damage checkpoint ; GO:0000077 | inferred from sequence or structural similarity with HGNC:30231 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:30231 CG9578 IPR007303:TIP41-like protein CG9578 11-Aug-17 DroID_v2017_08 Drer\tiprl Scer\TIP41 Cele\ZK688.9 Xtro\tiprl Mmus\Tiprl Hsap\TIPRL FBgn0261874 Z2-0115 - http://flybase.org/reports/FBgn0261874 gene - sleep ; GO:0030431 | inferred from mutant phenotype - Z2-0115 - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective FBgn0026872 CG14777 - http://flybase.org/reports/FBgn0026872 FBgn0064788 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 "EG:80H7.10, BcDNA:RH63812, CG14777" IPR007248:Mpv17/PMP22 CG14777 11-Aug-17 DroID_v2017_08 "Drer\pxmp2, Drer\mpv17, Drer\si:dkeyp-72e1.7, Drer\mpv17l2, Drer\si:ch211-120k19.1" "Scer\SYM1, Scer\YOR292C" - "Xtro\pxmp2, Xtro\mpv17l2" "Mmus\Mpv17l2, Mmus\Pxmp2, Mmus\Mpv17, Mmus\Mpv17l" "Hsap\PXMP2, Hsap\MPV17L, Hsap\MPV17L2, Hsap\MPV17" viable FBgn0004813 fs(2)ltoHM11 female sterile (2) ltoHM11 http://flybase.org/reports/FBgn0004813 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoHM11 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0001967 NimC3 Nimrod C3 http://flybase.org/reports/FBgn0001967 FBgn0032542 protein_coding_gene molecular_function ; GO:0003674 | no biological data available phagocytosis ; GO:0006909 | inferred from sequence or structural similarity with NimC1 integral component of membrane ; GO:0016021 | inferred from sequence model "CG16880, l(2)34Fa, BG:DS05899.2, l(2)k00811, l34Fa, br30, l(2)br30, NimC3, I(2)34Fa, nimC3" - CG16880 11-Aug-17 DroID_v2017_08 "Drer\pear1, Drer\zgc:158328, Drer\megf6a, Drer\scarf1, Drer\megf11, Drer\megf10, Drer\ccbe1, Drer\dkk2, Drer\esm1, Drer\dkk1a, Drer\tnfaip6, Drer\megf6b" - - "Xtro\megf11, Xtro\stab2, Xtro\tnfaip6" "Mmus\Megf10, Mmus\Megf11, Mmus\Megf6, Mmus\Egfem1, Mmus\Tnfaip6, Mmus\Pear1, Mmus\Dkk3, Mmus\Esm1, Mmus\Dkk2, Mmus\Stab1, Mmus\Scarf1" "Hsap\PEAR1, Hsap\TNFAIP6, Hsap\MEGF11, Hsap\MEGF10, Hsap\DKK2, Hsap\MEGF6, Hsap\SCARF1, Hsap\SCARF2" "lethal,recessive,viable" FBgn0021871 l(2)k13805 lethal (2) k13805 http://flybase.org/reports/FBgn0021871 - gene - - - l(2)k13805 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034002 CG8079 - http://flybase.org/reports/FBgn0034002 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay CG8079 "IPR000253:Forkhead-associated (FHA) domain, IPR000467:G-patch domain, IPR008984:SMAD/FHA domain" CG8079 11-Aug-17 DroID_v2017_08 "Drer\gpatch2, Drer\aggf1" Scer\SQS1 "Cele\Y55D9A.2, Cele\D1037.1" Xtro\aggf1 "Mmus\Gpatch2, Mmus\Son, Mmus\Aggf1" "Hsap\AGGF1, Hsap\GPATCH2, Hsap\SON" viable FBgn0066369 chyo chyorny http://flybase.org/reports/FBgn0066369 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available chyo - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,memory defective" FBgn0262609 CG43135 - http://flybase.org/reports/FBgn0262609 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43135, lincRNA.946" - CG43135 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259878 Fs Follistatin http://flybase.org/reports/FBgn0259878 protein_coding_gene - negative regulation of decapentaplegic signaling pathway ; GO:0090099 | inferred from direct assay negative regulation of activin receptor signaling pathway ; GO:0032926 | inferred from direct assay positive regulation of activin receptor signaling pathway ; GO:0032927 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG33466, CG12955, dFS, CG12956, Fs, dfs, dFol1, Fol1, fs" "IPR002350:Kazal domain, IPR003645:Follistatin-like, N-terminal" CG33466 11-Aug-17 DroID_v2017_08 "Drer\fstb, Drer\sparc, Drer\reck, Drer\fsta, Drer\sparcl1, Drer\tmeff1b, Drer\tmeff2b, Drer\tmeff1a, Drer\fstl3" - "Cele\agr-1, Cele\F29G6.1" "Xtro\fstl3, Xtro\fst, Xtro\sparc" "Mmus\Fst, Mmus\Spink13, Mmus\Fstl3, Mmus\Spink5, Mmus\Spink4, Mmus\Sparcl1, Mmus\Spink2, Mmus\Reck, Mmus\Spink6, Mmus\Spink1, Mmus\Sparc, Mmus\Spink7, Mmus\Spink12" "Hsap\SPARCL1, Hsap\SPINK6, Hsap\SPARC, Hsap\SPINK7, Hsap\RECK, Hsap\FST, Hsap\FSTL3, Hsap\SPINK1, Hsap\SPINK4, Hsap\SPINK5, Hsap\SPINK13" DRSC06259 E -0.431471755 1.276380601 2.969117166 1.169264284 0.336161645 -0.372515206 FBgn0033572 polyph polyphemus http://flybase.org/reports/FBgn0033572 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 phagocytosis ; GO:0006909 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 "CG12943, polyph" "IPR013057:Amino acid transporter, transmembrane domain" CG12943 11-Aug-17 DroID_v2017_08 "Drer\slc36a4, Drer\slc36a1" "Scer\AVT6, Scer\AVT3, Scer\AVT4" "Cele\skat-1, Cele\slc-36.5, Cele\slc-36.3, Cele\Y43F4B.7, Cele\slc-36.4, Cele\slc-36.2" "Xtro\slc36a1, Xtro\slc36a4" "Mmus\Slc36a3, Mmus\Slc36a1, Mmus\Slc36a2, Mmus\Slc36a4, Mmus\Slc38a7" "Hsap\SLC36A3, Hsap\SLC36A1, Hsap\SLC36A2, Hsap\SLC36A4, Hsap\SLC38A7" "immune response defective,short lived,conditional,viable" FBgn0053138 AGBE "1,4-Alpha-Glucan Branching Enzyme" http://flybase.org/reports/FBgn0053138 protein_coding_gene "1,4-alpha-glucan branching enzyme activity ; GO:0003844 | inferred from electronic annotation with InterPro:IPR006407 cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006048 hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR004193" glycogen biosynthetic process ; GO:0005978 | inferred from electronic annotation with InterPro:IPR006407 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype - "CG4023, CG33138, AGBE" "IPR004193:Glycoside hydrolase, family 13, N-terminal, IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR006048:Alpha-amylase/branching enzyme, C-terminal all beta, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR017853:Glycoside hydrolase superfamily, IPR006407:1,4-alpha-glucan-branching enzyme, GlgB" CG33138 11-Aug-17 DroID_v2017_08 "Drer\gbe1b, Drer\gbe1a" Scer\GLC3 Cele\T04A8.7 Xtro\gbe1 Mmus\Gbe1 Hsap\GBE1 "viable,fertile,long lived" DRSC06861 I 2.672299107 0.705485952 0.38423719 -0.311774029 -0.094217676 0.128247786 FBgn0039192 CG17784 - http://flybase.org/reports/FBgn0039192 protein_coding_gene - - - CG17784 IPR006631:Protein of unknown function DM4/12 CG17784 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259385 EP-1 - http://flybase.org/reports/FBgn0259385 gene - - - EP-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0259430 EP-536 - http://flybase.org/reports/FBgn0259430 gene - - - EP-536 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0262571 CG43111 - http://flybase.org/reports/FBgn0262571 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43111 - CG43111 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033490 CG12917 - http://flybase.org/reports/FBgn0033490 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - CG12917 IPR001604:DNA/RNA non-specific endonuclease CG12917 11-Aug-17 DroID_v2017_08 "Drer\LOC100333474, Drer\LOC103910196, Drer\endog" Scer\NUC1 Cele\cps-6 Xtro\LOC100490587 Mmus\Endog "Hsap\ENDOG, Hsap\EXOG" viable FBgn0000980 fs(2)HO260 female sterile (2) HO260 http://flybase.org/reports/FBgn0000980 - gene - - - "fs(2)260A, fs(2)HO260" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260060 2L2953 - http://flybase.org/reports/FBgn0260060 gene - - - 2L2953 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0259251 EP-A - http://flybase.org/reports/FBgn0259251 gene - - - EP-A - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0265539 CR44389 - http://flybase.org/reports/FBgn0265539 non_protein_coding_gene - - - "CR44389, lincRNA.332" - CR44389 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264328 CR43787 - http://flybase.org/reports/FBgn0264328 non_protein_coding_gene - - - CR43787 - CR43787 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000342 coc collapsed ocelli http://flybase.org/reports/FBgn0000342 - gene - - - coc - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "ocellus,ocellar bristle,abdomen,thorax,wing" FBgn0267893 CR46181 - http://flybase.org/reports/FBgn0267893 pseudogene_attribute - - - CR46181 - CR46181 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046125 E(To)1 E(To)1 http://flybase.org/reports/FBgn0046125 gene - - - E(To)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025929 hip7 hb-interacting protein 7 http://flybase.org/reports/FBgn0025929 - gene - - - hip7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050220 tRNA:Glu-CTC-2-2 transfer RNA:Glutamic acid-CTC 2-2 http://flybase.org/reports/FBgn0050220 tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "CR30220, AE002787.trna55-GluCTC, tRNA:E:CTC:AE002787-b, FBgn:0050220, chr2R.trna38-GluCTC, tRNA:Glu-CTC-2-2, tRNA:CR30220, tRNA-Glu-CTC-2-2, GAG" - CR30220 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051101 CG31101 - http://flybase.org/reports/FBgn0051101 protein_coding_gene - - - CG31101 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039665 CG2310 - http://flybase.org/reports/FBgn0039665 protein_coding_gene - - - CG2310 - CG2310 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0036697 rogdi rogdi http://flybase.org/reports/FBgn0036697 protein_coding_gene molecular_function ; GO:0003674 | no biological data available olfactory learning ; GO:0008355 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG7725, rogdi" IPR028241:RAVE subunit 2/Rogdi CG7725 11-Aug-17 DroID_v2017_08 Drer\rogdi - Cele\H14A12.3 Xtro\rogdi Mmus\Rogdi Hsap\ROGDI "memory defective,chemical sensitive,viable" FBgn0065883 l(2)SH0230 lethal (2) SH0230 http://flybase.org/reports/FBgn0065883 gene - - - "l(2)SH0230, l(2)SH2 0230" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051156 CG31156 - http://flybase.org/reports/FBgn0051156 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003029, InterPro:IPR012337" nucleobase-containing compound metabolic process ; GO:0006139 | inferred from electronic annotation with InterPro:IPR006641 - "CG5257, CG5253, CG31156" "IPR003029:S1 domain, IPR006641:YqgF/RNase H-like domain, IPR012340:Nucleic acid-binding, OB-fold, IPR012337:Ribonuclease H-like domain, IPR010994:RuvA domain 2-like, IPR023319:Tex-like protein, HTH domain, IPR023323:Tex-like domain, IPR018974:Tex-like protein, N-terminal, IPR022967:RNA-binding domain, S1, IPR032639:Tex protein, YqgF-like domain" CG31156 11-Aug-17 DroID_v2017_08 - - Cele\ZK973.1 "Xtro\eepd1, Xtro\srbd1" Mmus\Srbd1 Hsap\SRBD1 "viable,fertile" FBgn0264576 Pvr::Hsap\EGFR - http://flybase.org/reports/FBgn0264576 engineered_fusion_gene - - - Pvr::Hsap\EGFR - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060829 l(3)S050620 lethal (3) S050620 http://flybase.org/reports/FBgn0060829 gene - - - "0506/20, l(3)S050620" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0022258 l(2)k00909 lethal (2) k00909 http://flybase.org/reports/FBgn0022258 - gene - - - l(2)k00909 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034582 Cht9 Chitinase 9 http://flybase.org/reports/FBgn0034582 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 chitinase activity ; GO:0004568 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype chitin catabolic process ; GO:0006032 | inferred from direct assay wound healing ; GO:0042060 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay "Cht9, CG10531, DmCHT9, DmCht9" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG10531 11-Aug-17 DroID_v2017_08 "Drer\chia.2, Drer\si:ch211-226m16.2, Drer\chia.5, Drer\chia.1, Drer\srl, Drer\ovgp1" Scer\CTS2 "Cele\chil-4, Cele\chil-8, Cele\chil-20, Cele\lmd-4, Cele\cht-2, Cele\R09D1.14, Cele\chil-22, Cele\chil-9, Cele\lmd-5, Cele\chil-24, Cele\chil-12, Cele\chil-13, Cele\cht-1, Cele\chil-18, Cele\chil-19, Cele\chil-2, Cele\chil-27, Cele\chil-1, Cele\chil-21, Cele\chil-3, Cele\cht-3, Cele\chil-16, Cele\chil-7, Cele\K08F9.3, Cele\chil-5, Cele\chil-15, Cele\chil-11, Cele\chil-23, Cele\chil-6, Cele\chil-17, Cele\T19H5.6, Cele\chil-25, Cele\cht-4" "Xtro\ctbs, Xtro\LOC548945, Xtro\chit1, Xtro\srl, Xtro\chia" "Mmus\Chia1, Mmus\Chit1, Mmus\Ctbs, Mmus\Chil6, Mmus\Chil5, Mmus\Srl, Mmus\Chil4, Mmus\Chil1, Mmus\Ovgp1, Mmus\Chil3" "Hsap\OVGP1, Hsap\SRL, Hsap\CHI3L1, Hsap\CHIT1, Hsap\CHI3L2, Hsap\CHIA" viable FBgn0041247 Gr28a Gustatory receptor 28a http://flybase.org/reports/FBgn0041247 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "CG13787, Gr28A2, Gr28A1, 28A.1, GR28A.1, Gr28a, GR28a" IPR013604:7TM chemoreceptor CG13787 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - viable FBgn0030826 CG12995 - http://flybase.org/reports/FBgn0030826 protein_coding_gene - - - CG12995 - CG12995 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259407 EP-182 - http://flybase.org/reports/FBgn0259407 gene - - - EP-182 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta,ectopic" FBgn0262438 mir-1006 mir-1006 stem loop http://flybase.org/reports/FBgn0262438 miRNA_gene - miRNA mediated inhibition of translation ; GO:0035278 | inferred from direct assay - "miR-1006, mir-1006, dme-mir-1006, MIR-1006, CR42999, dme-miR-1006" - CR42999 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing margin,wing vein" FBgn0082318 LpR2::sev LpR2::sev http://flybase.org/reports/FBgn0082318 engineered_fusion_gene - - - LpR2::sev - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037167 CG11425 - http://flybase.org/reports/FBgn0037167 protein_coding_gene phosphatidate phosphatase activity ; GO:0008195 | non-traceable author statement phosphatidate phosphatase activity ; GO:0008195 | inferred from sequence or structural similarity with SGD:S000002911 lipid phosphatase activity ; GO:0042577 | inferred from biological aspect of ancestor with PANTHER:PTN000807400 phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000017950 phospholipid metabolic process ; GO:0006644 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 phospholipid dephosphorylation ; GO:0046839 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 phospholipid metabolic process ; GO:0006644 | inferred from sequence or structural similarity with SGD:S000002911 dephosphorylation ; GO:0016311 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 membrane ; GO:0016020 | inferred from sequence or structural similarity with SGD:S000002911 "WUN-like, CG11425, LPP-like" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG11425 11-Aug-17 DroID_v2017_08 "Drer\plpp1a, Drer\plpp5, Drer\plppr1, Drer\plpp2a, Drer\ppap2d, Drer\plpp3, Drer\plppr4a, Drer\plppr5b, Drer\plppr2b, Drer\LOC571722, Drer\plppr3b, Drer\LOC794598, Drer\plppr5a, Drer\plppr3a, Drer\plpp2b, Drer\plppr2a, Drer\plpp4" "Scer\LPP1, Scer\DPP1" "Cele\T28D9.3, Cele\F13E6.5, Cele\T06D8.3, Cele\F53C3.13" "Xtro\plpp1, Xtro\plpp3, Xtro\plpp5, Xtro\plpp2, Xtro\plpp4, Xtro\LOC100135382" "Mmus\Plppr2, Mmus\Plpp5, Mmus\Plppr4, Mmus\Plpp3, Mmus\Plpp4, Mmus\Plpp2, Mmus\Plppr5, Mmus\Plppr3, Mmus\Plppr1, Mmus\Plpp1" "Hsap\PLPPR3, Hsap\PLPP1, Hsap\PLPP2, Hsap\PLPPR4, Hsap\PLPP5, Hsap\PLPP4, Hsap\PLPPR5, Hsap\PLPPR2, Hsap\PLPPR1, Hsap\PLPP3" viable FBgn0029140 P(3)97C P(3)97C http://flybase.org/reports/FBgn0029140 gene - - - P(3)97C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015940 fs(3)2755 fs(3)2755 http://flybase.org/reports/FBgn0015940 - gene - - - "fs(3)1755, fs(3)2755" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,mitotic cell cycle defective" FBgn0033479 PIG-N Phosphatidylinositol glycan anchor biosynthesis class N http://flybase.org/reports/FBgn0033479 protein_coding_gene mannose-ethanolamine phosphotransferase activity ; GO:0051377 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 "PIG-N, CG2292" "IPR002591:Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase, IPR007070:GPI ethanolamine phosphate transferase 1, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR017852:GPI ethanolamine phosphate transferase 1, C-terminal" CG2292 11-Aug-17 DroID_v2017_08 Drer\pign Scer\MCD4 Cele\Y54E10BR.1 Xtro\pign Mmus\Pign Hsap\PIGN FBgn0060410 l(3)S130313a lethal (3) S130313a http://flybase.org/reports/FBgn0060410 gene - - - "1428/03, 1303/13, l(3)S130313a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0000261 Cat Catalase http://flybase.org/reports/FBgn0000261 "FBgn0011460, FBgn0026841" protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 catalase activity ; GO:0004096 | inferred from direct assay antioxidant activity ; GO:0016209 | non-traceable author statement catalase activity ; GO:0004096 | inferred from sequence or structural similarity with HGNC:1516 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR011614, InterPro:IPR018028, InterPro:IPR020835, InterPro:IPR024711 determination of adult lifespan ; GO:0008340 | traceable author statement paracrine signaling ; GO:0038001 | inferred from mutant phenotype reactive oxygen species metabolic process ; GO:0072593 | inferred from mutant phenotype aging ; GO:0007568 | traceable author statement response to hydrogen peroxide ; GO:0042542 | traceable author statement response to hydrogen peroxide ; GO:0042542 | inferred from mutant phenotype heart morphogenesis ; GO:0003007 | inferred from mutant phenotype regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype hydrogen peroxide catabolic process ; GO:0042744 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 response to ethanol ; GO:0045471 | inferred from mutant phenotype" peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000157252 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:1516 inferred from sequence model mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000157252 "Cat, CAT, CG6871, cat, U00145, DMCATHPO, CT21282, bs36h11.y1, DROCATHPO, CATA, CatA, catalase" "IPR010582:Catalase immune-responsive domain, IPR018028:Catalase, mono-functional, haem-containing, IPR002226:Catalase haem-binding site, IPR011614:Catalase core domain, IPR020835:Catalase-like domain, IPR024708:Catalase active site, IPR024711:Catalase, mono-functional, haem-containing, clades 1 and 3" CG6871 11-Aug-17 DroID_v2017_08 Drer\cat "Scer\CTA1, Scer\CTT1" "Cele\ctl-3, Cele\ctl-2, Cele\ctl-1" "Xtro\cat.2, Xtro\cat.1" Mmus\Cat Hsap\CAT adult stage " larval stage--pupal stage , larval stage--adult stage , embryonic stage | stage <7 , embryonic stage -- adult stage , adult stage , embryonic stage | stage >=7 , larval stage | third instar " " salivary gland

, ovary

, organism

, foregut && midgut && hindgut | restricted

, sense organ

, oenocyte

, embryonic oenocyte

, testis

, fat body

, dorsal mesothoracic disc

" "decreased cell number,conditional,oxidative stress response defective,lethal,viable,fertile,partially lethal - majority die,wild-type,chemical resistant,recessive,chemical sensitive,short lived,visible,locomotor rhythm defective" "lamellocyte,conditional,adult heart,RU486 conditional,intestinal stem cell,enteroendocrine cell,supernumerary,enterocyte,adult midgut,trichogen cell,progressive" FBgn0260323 GSd488 - http://flybase.org/reports/FBgn0260323 gene - - - GSd488 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0043030 l(2)42Da lethal (2) 42Da http://flybase.org/reports/FBgn0043030 gene - - - l(2)42Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259237 CG42335 - http://flybase.org/reports/FBgn0259237 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "CG42335, CG13420, CG5845, CG31177" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG42335 11-Aug-17 DroID_v2017_08 "Drer\anpepa, Drer\erap1a, Drer\erap1b, Drer\si:ch211-149p5.1, Drer\anpepb, Drer\erap2, Drer\si:ch211-198g19.1, Drer\si:ch211-276a23.5, Drer\lnpep, Drer\si:ch211-106j24.1, Drer\npepps, Drer\enpep" "Scer\TMA108, Scer\APE2, Scer\AAP1" "Cele\AC3.5, Cele\T16G12.1, Cele\T12E12.6, Cele\VB0395L.1, Cele\Y42A5A.1, Cele\mnp-1, Cele\pam-1, Cele\T07F10.1, Cele\F49B2.6, Cele\R03G8.4, Cele\Y53F4B.20, Cele\Y67D8C.9, Cele\R03G8.6" "Xtro\erap1, Xtro\lnpep, Xtro\anpep, Xtro\npepps, Xtro\enpep, Xtro\lvrn" "Mmus\Anpep, Mmus\Lvrn, Mmus\Lnpep, Mmus\Trhde, Mmus\Erap1, Mmus\Npepps, Mmus\Enpep" "Hsap\TRHDE, Hsap\ERAP2, Hsap\ANPEP, Hsap\LNPEP, Hsap\NPEPPS, Hsap\ERAP1, Hsap\LVRN, Hsap\ENPEP" DRSC25666 K 0.792287047 0.037779505 -0.199822583 0.151143308 -0.49661553 1.584675305 FBgn0025881 snoRNA:Me18S-A1576 - http://flybase.org/reports/FBgn0025881 "FBgn0051877, FBgn0063390" snoRNA_gene - - - "U15snoRNA, Z5 snoRNA, snoRNA:U15, CR31877, snoRNA:Me18S-A1576, Me18S-A1576(Z5), snoRNA:Z5, Me18S-A1576" - CR31877 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259825 ifm(2)RS9 indirect flight muscle (2) RS9 http://flybase.org/reports/FBgn0259825 gene - adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS9 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable indirect flight muscle FBgn0038617 CG12333 - http://flybase.org/reports/FBgn0038617 protein_coding_gene - maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000458000 lateral inhibition ; GO:0046331 | inferred from mutant phenotype maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000458000 "PeBoW complex ; GO:0070545 | inferred from biological aspect of ancestor with PANTHER:PTN000458000 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000458000" CG12333 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like" CG12333 11-Aug-17 DroID_v2017_08 Drer\wdr37 "Scer\YTM1, Scer\MDV1" Cele\C05D2.10 Xtro\wdr37 Mmus\Wdr37 Hsap\WDR37 "visible,partially lethal - majority die,some die during pupal stage" chaeta FBgn0085719 CG41603 - http://flybase.org/reports/FBgn0085719 protein_coding_gene - - - CG41603 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043485 l(3)66EFa lethal (3) 66EFa http://flybase.org/reports/FBgn0043485 gene - - - l(3)66EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028487 f-cup flyers-cup http://flybase.org/reports/FBgn0028487 protein_coding_gene - - - "BcDNA:GH09045, CG9611, f-cup" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG9611 11-Aug-17 DroID_v2017_08 Drer\lrrc40 - - Xtro\lrrc40 Mmus\Lrrc40 Hsap\LRRC40 viable DRSC14139 E -1.134327234 0.237776169 -1.264695966 2.991555355 0.714991115 -0.192396682 FBgn0259593 B2031 - http://flybase.org/reports/FBgn0259593 gene - - - B2031 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0011987 tRNA:SeC-TCA-1-1 transfer RNA:Selenocysteine-TCA 1-1 http://flybase.org/reports/FBgn0011987 "FBgn0050024, FBgn0050256, FBgn0060051" tRNA_gene UGA codon-amino acid adaptor activity ; GO:0033415 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033415 cytosol ; GO:0005829 | inferred by curator from GO:0033415 "Sec tRNA[[Ser]Sec], SeCys-tRNA, tRNA[[Ser]Sec], AE002787.trna26-SeC(e)TCA, tRNA:SeC:TCA:AE002787, CR30256, CR30024, tRNA:SeCys, Sec tRNA, tRNA[SeC], chr2R:6873460..6873672, chr2R.trna85-SeC(e)TCA, tRNA-SeC-TCA-1-1, tRNA:SeC-TCA-1-1, tRNA:SeC" - CR30024 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014039 Su(tor)1-106 Su(tor)1-106 http://flybase.org/reports/FBgn0014039 - gene - - - Su(tor)1-106 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267810 CR46135 - http://flybase.org/reports/FBgn0267810 non_protein_coding_gene - - - CR46135 - CR46135 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040637 CG11458 - http://flybase.org/reports/FBgn0040637 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model CG11458 - CG11458 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0024905 anon-H31 anon-H31 http://flybase.org/reports/FBgn0024905 - gene - - - "cDNA H31, anon-H31" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036029 CG16719 - http://flybase.org/reports/FBgn0036029 protein_coding_gene - mesoderm development ; GO:0007498 | non-traceable author statement - CG16719 "IPR010441:CH-like domain in sperm protein, IPR001715:Calponin homology domain" CG16719 11-Aug-17 DroID_v2017_08 "Drer\spata4, Drer\zgc:66426" - - - "Mmus\6430531B16Rik, Mmus\Spef1" Hsap\SPEF1 viable FBgn0085833 CR42206 - http://flybase.org/reports/FBgn0085833 non_protein_coding_gene - - - CR42206 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002676 mat(2)syn-D maternal effect syncytial blastoderm arrest D http://flybase.org/reports/FBgn0002676 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)synPA75, mat(2)syn-D" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0041225 Gr94a Gustatory receptor 94a http://flybase.org/reports/FBgn0041225 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr94E1, 94E.1, CG31280, GR94E.1, Gr94a, GR94a" IPR013604:7TM chemoreceptor CG31280 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - "viable,fertile" DRSC13597 E 0.389268211 1.304535049 2.010941785 0.006495529 -0.377827672 -0.191876249 FBgn0065199 l(2)SH2312 lethal (2) SH2312 http://flybase.org/reports/FBgn0065199 gene - - - "l(2)SH2312, l(2)SH2 2312" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010790 l(3)02946 lethal (3) 02946 http://flybase.org/reports/FBgn0010790 - gene - - - l(3)02946 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0038917 CG6678 - http://flybase.org/reports/FBgn0038917 protein_coding_gene - - - CG6678 "IPR000408:Regulator of chromosome condensation, RCC1, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG6678 11-Aug-17 DroID_v2017_08 "Drer\rcbtb2, Drer\wbscr16, Drer\rpgrb, Drer\als2b, Drer\rcc1, Drer\als2a, Drer\ftr97, Drer\sergef, Drer\rpgra, Drer\rccd1, Drer\rcbtb1, Drer\herc1, Drer\herc2" "Scer\SRM1, Scer\FMP25, Scer\ATS1" "Cele\glo-4, Cele\K11D2.1" "Xtro\rcbtb1, Xtro\herc1, Xtro\wbscr16, Xtro\rcc1, Xtro\nek9, Xtro\als2, Xtro\rcbtb2, Xtro\als2cl, Xtro\herc2" "Mmus\Rcbtb2, Mmus\Als2, Mmus\Rcc1, Mmus\Rpgr, Mmus\Nek9, Mmus\Rccd1, Mmus\Gm15800, Mmus\Herc2, Mmus\Sergef, Mmus\Herc1, Mmus\Rcbtb1, Mmus\Wbscr16" "Hsap\NEK9, Hsap\RCC1, Hsap\HERC2, Hsap\HERC1, Hsap\RCCD1, Hsap\RCBTB2, Hsap\ALS2, Hsap\RCBTB1, Hsap\RPGR, Hsap\SERGEF, Hsap\HECTD4, Hsap\RCC1L" viable FBgn0026175 SkpC SKP1-related C http://flybase.org/reports/FBgn0026175 FBgn0031073 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000002736 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with SGD:S000002736 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with SGD:S000002736 "CG11941, dskpC, Skp, SkpC, skpC" "IPR011333:SKP1/BTB/POZ domain, IPR001232:S-phase kinase-associated protein 1-like, IPR016072:SKP1 component, dimerisation, IPR016073:SKP1 component, POZ domain, IPR016897:S-phase kinase-associated protein 1" CG11941 11-Aug-17 DroID_v2017_08 Drer\skp1 "Scer\ELC1, Scer\SKP1" "Cele\skr-19, Cele\skr-20, Cele\skr-12, Cele\skr-13, Cele\skr-3, Cele\skr-21, Cele\skr-6, Cele\skr-9, Cele\skr-15, Cele\skr-14, Cele\skr-8, Cele\skr-4, Cele\skr-10, Cele\skr-5, Cele\skr-2, Cele\skr-18, Cele\skr-7, Cele\skr-1, Cele\skr-16, Cele\skr-17" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0000176 Bg Bag http://flybase.org/reports/FBgn0000176 - gene - - - "Uw, Bg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "wing,wing vein,wing vein L3,wing vein L4,wing vein L5,crossvein,wing basal cell 1,anterior crossvein" FBgn0067854 abz abruzzi http://flybase.org/reports/FBgn0067854 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available abz - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "egg chamber,germline clone,oocyte nucleus" FBgn0265550 CR44400 - http://flybase.org/reports/FBgn0265550 non_protein_coding_gene - - - CR44400 - CR44400 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036310 CG10969 - http://flybase.org/reports/FBgn0036310 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10969 - CG10969 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267879 CR46167 - http://flybase.org/reports/FBgn0267879 pseudogene_attribute - - - "CR46167, CG12717-related" - CR46167 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010612 ATPsynG ATP synthase http://flybase.org/reports/FBgn0010612 "FBgn0025552, FBgn0032325, FBgn0047026, FBgn0047151" protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000273103 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000006224" ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000006224 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:O75964 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000273103 "lipid particle ; GO:0005811 | inferred from direct assay mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with UniProtKB:O75964 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from biological aspect of ancestor with PANTHER:PTN000273103" "I(2)06225, anon-EST:Posey10, CG6105, BcDNA:RH28372, BcDNA:RE20862, l(2)06225, ATPN, ATPsynG" "IPR006808:ATP synthase, F0 complex, subunit G, mitochondrial, IPR016702:Mitochondrial ATP synthase subunit g, animal" CG6105 11-Aug-17 DroID_v2017_08 Drer\atp5l Scer\ATP20 "Cele\asg-2, Cele\asg-1" Xtro\atp5l Mmus\Atp5l "Hsap\ATP5L, Hsap\ATP5L2" "lethal,recessive" FBgn0085462 CG34433 - http://flybase.org/reports/FBgn0085462 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34433, CG15541" - CG34433 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014893 Wow Weakener of white http://flybase.org/reports/FBgn0014893 - gene - - - Wow - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,sterile,lethal,suppressor of variegation" "testis,wing,pigment cell,Malpighian tubule" FBgn0259103 dar4 dendritic arbor reduction 4 http://flybase.org/reports/FBgn0259103 gene - positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype - dar4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065930 l(2)SH0136 lethal (2) SH0136 http://flybase.org/reports/FBgn0065930 gene - - - "l(2)SH0136, l(2)SH2 0136" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065296 l(2)SH1998 lethal (2) SH1998 http://flybase.org/reports/FBgn0065296 gene - - - "l(2)SH1998, l(2)SH2 1998" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024366 CG11409 - http://flybase.org/reports/FBgn0024366 - protein_coding_gene - - - "EG:8D8.2, CG11409" - CG11409 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004004 wd wavoid http://flybase.org/reports/FBgn0004004 - gene - - - wd - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0003751 trk trunk http://flybase.org/reports/FBgn0003751 - protein_coding_gene torso binding ; GO:0005122 | traceable author statement "maternal determination of anterior/posterior axis, embryo ; GO:0008358 | non-traceable author statement torso signaling pathway ; GO:0008293 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement terminal region determination ; GO:0007362 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | traceable author statement" extracellular region ; GO:0005576 | inferred from sequence or structural similarity "fs(2)trunk, CG5619, trk, Trk" IPR029034:Cystine-knot cytokine CG5619 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && oogenesis stage , embryonic stage | 0-2 hr " " nurse cell

,

ubiquitous " "wild-type,developmental rate defective,lethal,maternal effect,female sterile,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,terminal phenotype,germline clone,non-rescuable maternal effect,viable" "abdominal segment 9,abdominal segment 10,telson,labrum,ocular segment,cephalic furrow,filzkorper,embryonic segment,abdomen,embryonic/first instar larval cuticle,maternal effect,embryonic labral segment,posterior endoderm,posterior midgut primordium,extended germ band embryo,abdominal segment 8,abdominal 8 ventral denticle belt,abdominal 9 ventral denticle belt,embryonic abdominal segment 8,embryo,germline clone,posterior,ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7" FBgn0001633 l(1)dn13 lethal (1) discs normal 13 http://flybase.org/reports/FBgn0001633 - gene - - - "l(1)d.norm.-13, l(1)dn13" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0086048 snoRNA:Me28S-U3344b - http://flybase.org/reports/FBgn0086048 snoRNA_gene - - - "snoRNA:Me28S-U3344b, Me28S-Um3344b, CR34677, mg28S-3344" - CR34677 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062527 l(3)88EFe lethal (3) 88EFe http://flybase.org/reports/FBgn0062527 gene - - - l(3)88EFe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0002085 l(2)49Fo lethal (2) 49Fo http://flybase.org/reports/FBgn0002085 - gene - - - "l(2)vr16, l(2)49Fo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0022990 p94 p94 http://flybase.org/reports/FBgn0022990 - gene nuclear localization sequence binding ; GO:0008139 | inferred from direct assay - - p94 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033717 CG8839 - http://flybase.org/reports/FBgn0033717 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay CG8839 IPR023631:Amidase signature domain CG8839 11-Aug-17 DroID_v2017_08 "Drer\faah2a, Drer\faah, Drer\faah2b" Scer\AMD2 "Cele\faah-4, Cele\Y53F4B.18, Cele\faah-3, Cele\faah-5, Cele\faah-2, Cele\faah-6" "Xtro\faah.2, Xtro\faah2, Xtro\faah.1, Xtro\faah.3" Mmus\Faah "Hsap\FAAH2, Hsap\FAAH" viable FBgn0051356 tRNA:Thr-TGT-1-1 transfer RNA:Threonine-TGT 1-1 http://flybase.org/reports/FBgn0051356 tRNA_gene ACA codon-amino acid adaptor activity ; GO:0033439 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033439 cytosol ; GO:0005829 | inferred by curator from GO:0033439 "AE002708.trna4-ThrTGT, tRNA[Thr][[3]], tRNA:thr3:87BC, tRNA:T3:87BC, tRNA:T:TGT:AE002708-a, CR31356, tRNA[[Thr]], chr3R.trna10-ThrTGT, tRNA-Thr-TGT-1-1, tRNA:Thr-TGT-1-1, tRNA:CR31356, ACA" - CR31356 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022369 Pt-4 Larval protein-4 http://flybase.org/reports/FBgn0022369 - gene - - - Pt-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058207 CG40207 - http://flybase.org/reports/FBgn0058207 protein_coding_gene - - - CG40207 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065034 Antp::Dmag\Antp Antp::Dmag\Antp http://flybase.org/reports/FBgn0065034 engineered_fusion_gene - - - Antp::Dmag\Antp - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "antenna,leg,ectopic,Keilin's organ,denticle belt,embryonic/first instar larval cuticle,ventral" FBgn0017437 anon-28Cb anon-28Cb http://flybase.org/reports/FBgn0017437 - gene - - - anon-28Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037115 CG11249 - http://flybase.org/reports/FBgn0037115 protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 potassium ion binding ; GO:0030955 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 pyruvate kinase activity ; GO:0004743 | inferred from biological aspect of ancestor with PANTHER:PTN000212670" glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 CG11249 "IPR001697:Pyruvate kinase, IPR011037:Pyruvate kinase-like, insert domain, IPR015793:Pyruvate kinase, barrel, IPR015795:Pyruvate kinase, C-terminal" CG11249 11-Aug-17 DroID_v2017_08 "Drer\pkma, Drer\pkmb" "Scer\PYK2, Scer\CDC19" "Cele\pyk-2, Cele\pyk-1" "Xtro\pklr, Xtro\pkm" "Mmus\Pkm, Mmus\Pklr" "Hsap\PKM, Hsap\PKLR" viable FBgn0000283 Cp190 Centrosomal protein 190kD http://flybase.org/reports/FBgn0000283 FBgn0014463 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24147 microtubule binding ; GO:0008017 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P08970 inferred from physical interaction with UniProtKB:Q86B87 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SYK5 chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Sas-4 DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Ibf2 inferred from physical interaction with Ibf1 POZ domain binding ; GO:0031208 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity regulation of cytoskeleton organization ; GO:0051493 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype gene looping ; GO:0090202 | inferred from mutant phenotype nuclear axial expansion ; GO:0035191 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 positive regulation of chromatin silencing ; GO:0031937 | inferred from genetic interaction with w nucleus ; GO:0005634 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay spindle microtubule ; GO:0005876 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay pericentriolar material ; GO:0000242 | inferred from direct assay condensed chromosome ; GO:0000793 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay "CP190, CEN190, Cen190, CP-190, Rb188, CG6384, CP-60, dmap190, DMAP190, Bx63, Dmap190, DMAP-190, Cen185, Map190, AbS1-4, Cp190, E(mod)4-1, Bx-63, cp190, CP190_DROME, DMAP 190" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type" CG6384 11-Aug-17 DroID_v2017_08 "Drer\zbtb11, Drer\rp1, Drer\leo1" Scer\YFR016C - Xtro\leo1 "Mmus\E4f1, Mmus\Leo1, Mmus\Dmp1, Mmus\Rp1, Mmus\Ibsp" "Hsap\IBSP, Hsap\LEO1, Hsap\DMP1, Hsap\ZBTB37, Hsap\RP1, Hsap\E4F1" " adult stage | female , embryonic stage | 0-16 hr " embryonic stage | blastoderm "viable,lethal,partially,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,partially lethal - majority die,lethal - all die during embryonic stage,lethal - all die during third instar larval stage,heat sensitive" "cleavage nucleus,centrosome,microtubule,eye,tarsal segment,pretarsus,embryonic/larval salivary gland | third instar larval stage" FBgn0037995 CG3809 - http://flybase.org/reports/FBgn0037995 protein_coding_gene adenosine kinase activity ; GO:0004001 | inferred from sequence or structural similarity with MGD:Adk; MGI:MGI:87930 purine ribonucleoside salvage ; GO:0006166 | inferred from electronic annotation with InterPro:IPR001805 AMP biosynthetic process ; GO:0006167 | inferred from sequence or structural similarity with MGD:Adk; MGI:MGI:87930 cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.193, CG3809, DmAdk1" "IPR029056:Ribokinase-like, IPR001805:Adenosine kinase, IPR011611:Carbohydrate kinase PfkB" CG3809 11-Aug-17 DroID_v2017_08 "Drer\adkb, Drer\adka" Scer\ADO1 Cele\R07H5.8 Xtro\adk Mmus\Adk Hsap\ADK viable FBgn0013671 ms(3)neo94 ms(3)neo94 http://flybase.org/reports/FBgn0013671 - gene - - - ms(3)neo94 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0026259 eIF5B eukaryotic translation initiation factor 5B http://flybase.org/reports/FBgn0026259 "FBgn0035446, FBgn0035447, FBgn0062068" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity DEAD/H-box RNA helicase binding ; GO:0017151 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P09052" translational initiation ; GO:0006413 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity "cIF2, IF2, dIF2, CG10840, yIF2, A1, CG14970, anon-WO0118547.362, eIF5B, Eif5b" "IPR000795:Transcription factor, GTP-binding domain, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR005225:Small GTP-binding protein domain, IPR009000:Translation protein, beta-barrel domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR023115:Translation initiation factor IF- 2, domain 3" CG10840 11-Aug-17 DroID_v2017_08 Drer\eif5b Scer\FUN12 Cele\iffb-1 "Xtro\eif5b, Xtro\hbs1l" Mmus\Eif5b Hsap\EIF5B "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" DRSC08710 IE 1.005846276 2.475974956 3.925326219 -1.867289027 -1.156522938 1.33784455 FBgn0000502 dsr disrupted http://flybase.org/reports/FBgn0000502 - gene - - - dsr - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0062254 Su(Sd)4a-2 Suppressor of SD 4a-2 http://flybase.org/reports/FBgn0062254 gene - - - "Su(SD)[4a-2], Su(Sd)4a-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0029017 l(3)77CDh lethal (3) 77CDh http://flybase.org/reports/FBgn0029017 gene - - - l(3)77CDh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039757 RpS7 Ribosomal protein S7 http://flybase.org/reports/FBgn0039757 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000554 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000554 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000554 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "CG1883, RpS7" IPR000554:Ribosomal protein S7e CG1883 11-Aug-17 DroID_v2017_08 Drer\rps7 "Scer\RPS7A, Scer\RPS7B" Cele\rps-7 Xtro\rps7 Mmus\Rps7 Hsap\RPS7 lethal DRSC15394 EK -0.491497248 0.842551401 4.152421541 -1.946055425 1.753770356 2.947685242 FBgn0260388 CG42514 - http://flybase.org/reports/FBgn0260388 protein_coding_gene adenylate cyclase activity ; GO:0004016 | non-traceable author statement transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "CG32158, AC, CG42514, CG4526" "IPR020846:Major facilitator superfamily domain, IPR011701:Major facilitator superfamily" CG42514 11-Aug-17 DroID_v2017_08 "Drer\LOC100002406, Drer\LOC557306, Drer\si:ch211-262i1.4, Drer\zgc:174356, Drer\hiat1b, Drer\slc46a3, Drer\hiat1a, Drer\slc46a1, Drer\si:dkey-5g14.1" Scer\YJL163C "Cele\F40F9.5, Cele\acy-4, Cele\Y4C6B.5, Cele\acy-3, Cele\Y43F8A.5, Cele\acy-2, Cele\C46C11.2" "Xtro\slc46a1, Xtro\slc46a2, Xtro\mfsd14b, Xtro\mfsd14a" "Mmus\Slc46a2, Mmus\Mfsd14a, Mmus\Slc46a1, Mmus\Slc46a3, Mmus\Mfsd14b, Mmus\Adcy5" "Hsap\MFSD14A, Hsap\SLC46A1, Hsap\ADCY5, Hsap\SLC46A2, Hsap\MFSD14B, Hsap\SLC46A3" "viable,fertile" FBgn0027170 l(2)E105 lethal (2) E105 http://flybase.org/reports/FBgn0027170 - gene - - - l(2)E105 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020786 ri-s radius incompletus-similis http://flybase.org/reports/FBgn0020786 - gene - - - ri-s - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265834 CG44623 - http://flybase.org/reports/FBgn0265834 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lincRNA.354, CG44623" - CG44623 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265883 CR44672 - http://flybase.org/reports/FBgn0265883 non_protein_coding_gene - - - "CR44672, lincRNA.609" - CR44672 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260254 GSd227 - http://flybase.org/reports/FBgn0260254 gene - - - GSd227 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0039252 CG11771 - http://flybase.org/reports/FBgn0039252 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000211184 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001567 peptide metabolic process ; GO:0006518 | inferred from biological aspect of ancestor with PANTHER:PTN000211184 mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN000211242 "anon-EST:Posey100, CG11771" IPR001567:Peptidase M3A/M3B catalytic domain CG11771 11-Aug-17 DroID_v2017_08 "Drer\nln, Drer\thop1" Scer\PRD1 Cele\ZK550.3 "Xtro\thop1, Xtro\nln" "Mmus\Thop1, Mmus\Nln" "Hsap\NLN, Hsap\THOP1" viable DRSC27732 K -0.092766066 -0.118831995 -0.233096141 0.985833028 -1.793622006 0.161078805 FBgn0066320 1360\T 1360 element transposase http://flybase.org/reports/FBgn0066320 transposable_element_gene transposase activity ; GO:0004803 | inferred from electronic annotation with InterPro:IPR021896 "transposition, DNA-mediated ; GO:0006313 | inferred from electronic annotation with InterPro:IPR021896" - 1360\T IPR021896:Transposase protein - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011067 l(1)Q20 lethal (1) Q20 http://flybase.org/reports/FBgn0011067 FBgn0010210 gene - - - l(1)Q20 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263048 CG43343 - http://flybase.org/reports/FBgn0263048 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR011128, InterPro:IPR017751 protein homodimerization activity ; GO:0042803 | inferred from electronic annotation with InterPro:IPR017751 glycerol-3-phosphate dehydrogenase [NAD+] activity ; GO:0004367 | inferred from sequence or structural similarity with HGNC:4455" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006109 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006109, InterPro:IPR006168, InterPro:IPR008927, InterPro:IPR011128, InterPro:IPR013328, InterPro:IPR017751 glycerol-3-phosphate catabolic process ; GO:0046168 | inferred from electronic annotation with InterPro:IPR011128 glycerol-3-phosphate metabolic process ; GO:0006072 | inferred from sequence or structural similarity with MGI:MGI:95679" glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR006168 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:4455 "CG43343, CG18427, NEST:bs15d11, NEST:bs16c09, CG31169, gpdh-3" "IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR006168:Glycerol-3-phosphate dehydrogenase, NAD-dependent, IPR017751:Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic, IPR006109:Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal, IPR013328:6-phosphogluconate dehydrogenase, domain 2, IPR011128:Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal, IPR016040:NAD(P)-binding domain" CG43343 11-Aug-17 DroID_v2017_08 "Drer\gpd1b, Drer\gpd1c, Drer\gpd1l, Drer\gpd1a" "Scer\GPD1, Scer\GPD2" "Cele\gpdh-1, Cele\gpdh-2" "Xtro\gpd1, Xtro\gpd1l" "Mmus\Gpd1, Mmus\Gpd1l" "Hsap\GPD1L, Hsap\GPD1" viable FBgn0024600 roam roaming http://flybase.org/reports/FBgn0024600 - gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available roam - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,ventral nerve cord,Bolwig nerve,Bolwig organ" FBgn0028940 Cyp28a5 Cyp28a5 http://flybase.org/reports/FBgn0028940 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891 electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972" - "28a5, cyp28a5, gh10483, BG:DS00180.11, DS00180.11, BEST:GH10483, CG8864, Cyp28a5, Cyp28A5, CYP28a5" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV, IPR017972:Cytochrome P450, conserved site" CG8864 11-Aug-17 DroID_v2017_08 "Drer\cyp3c2, Drer\tbxas1, Drer\cyp3a65, Drer\cyp3c1, Drer\cyp3c3, Drer\cyp3c4" "Scer\DIT2, Scer\ERG11" "Cele\cyp-25A1, Cele\cyp-13B1, Cele\cyp-13A12, Cele\cyp-25A3, Cele\cyp-13B2, Cele\cyp-13A5, Cele\cyp-25A6, Cele\cyp-13A10, Cele\cyp-13A11, Cele\cyp-13A8, Cele\cyp-13A7, Cele\cyp-13A6, Cele\cyp-13A2, Cele\cyp-13A1, Cele\cyp-25A2, Cele\cyp-44A1, Cele\cyp-13A4, Cele\cyp-13A3, Cele\cyp-25A4, Cele\cyp-43A1" "Xtro\cyp3a5, Xtro\cyp3a4, Xtro\tbxas1, Xtro\LOC100494419" "Mmus\Cyp3a11, Mmus\Cyp3a25, Mmus\Cyp3a41b, Mmus\Cyp3a13, Mmus\Cyp3a59, Mmus\Cyp3a57, Mmus\Ptgis, Mmus\Cyp3a44, Mmus\Cyp3a41a, Mmus\Cyp3a16, Mmus\Tbxas1" "Hsap\PTGIS, Hsap\CYP3A43, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A5, Hsap\CYP3A4, Hsap\TBXAS1, Hsap\CYP3A7" FBgn0002496 l(3)SG57 lethal (3) SG57 http://flybase.org/reports/FBgn0002496 - gene - - - "l(3)7m147, l(3)SG57" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0035181 CG9205 - http://flybase.org/reports/FBgn0035181 protein_coding_gene - - - CG9205 "IPR000648:Oxysterol-binding protein, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG9205 11-Aug-17 DroID_v2017_08 "Drer\LOC100334085, Drer\osbpl10, Drer\osbpl11" "Scer\OSH7, Scer\OSH6" - "Xtro\osbpl11, Xtro\osbpl10" "Mmus\Osbpl10, Mmus\Osbpl11" "Hsap\OSBPL10, Hsap\OSBPL11" viable FBgn0013301 ProtB Protamine B http://flybase.org/reports/FBgn0013301 "FBgn0010308, FBgn0063256" protein_coding_gene DNA binding ; GO:0003677 | inferred from sequence or structural similarity "sperm chromatin condensation ; GO:0035092 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from genetic interaction with ProtA spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from direct assay" chromatin ; GO:0000785 | inferred from direct assay "BG:DS03431.3, mst35b, CG4478, BcDNA:GH11850, protB, ProtB, Mst35Bb, prot-B, dProtB, MST35Bb" "IPR009071:High mobility group box domain, IPR024460:Protamine-like" CG4478 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,viable" FBgn0030596 CG12398 - http://flybase.org/reports/FBgn0030596 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" chorion ; GO:0042600 | inferred from direct assay "CG12398, Dm GMCgamma1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG12398 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0039235 CG10899 - http://flybase.org/reports/FBgn0039235 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from electronic annotation with InterPro:IPR018338 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR018338 - "BcDNA:AT02719, CG10899" "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class, IPR018338:Carbonic anhydrase, alpha-class, conserved site" CG10899 11-Aug-17 DroID_v2017_08 "Drer\ptprga, Drer\ca6, Drer\ca5a, Drer\ca9, Drer\ca15b, Drer\ca4a, Drer\ca10b, Drer\ca4c, Drer\ca15a, Drer\ca15c, Drer\ca14, Drer\ca10a, Drer\ca12, Drer\ca7, Drer\si:ch211-173d10.4, Drer\ca8, Drer\zgc:153760, Drer\ca4b, Drer\cahz, Drer\car15, Drer\ca16b, Drer\ca2" - "Cele\cah-3, Cele\cah-4, Cele\cah-5, Cele\cah-6" "Xtro\ca14, Xtro\ca6, Xtro\ca5b, Xtro\ca7, Xtro\ca4, Xtro\ca3, Xtro\LOC779564, Xtro\ca11, Xtro\ca10, Xtro\ca12, Xtro\ca1, Xtro\ca8, Xtro\ca2" "Mmus\Car10, Mmus\Car2, Mmus\Ptprg, Mmus\Car1, Mmus\Car14, Mmus\Car9, Mmus\Car15, Mmus\Car8, Mmus\Car3, Mmus\Car4, Mmus\Car6, Mmus\Car7, Mmus\Car13, Mmus\Car5a, Mmus\Car12, Mmus\Car11, Mmus\Car5b" "Hsap\CA14, Hsap\CA3, Hsap\CA4, Hsap\CA6, Hsap\CA7, Hsap\CA5B, Hsap\CA5A, Hsap\CA9, Hsap\CA13, Hsap\CA12, Hsap\CA10, Hsap\CA1, Hsap\CA2, Hsap\CA11, Hsap\CA8, Hsap\PTPRG" viable FBgn0029588 CG14798 - http://flybase.org/reports/FBgn0029588 protein_coding_gene - regulation of mitochondrial membrane permeability involved in programmed necrotic cell death ; GO:1902445 | inferred from electronic annotation with InterPro:IPR032870 cellular response to DNA damage stimulus ; GO:0006974 | inferred from electronic annotation with InterPro:IPR032870 mitochondrial matrix ; GO:0005759 | inferred from electronic annotation with InterPro:IPR032870 "BcDNA:RE57135, CG14798" IPR032870:Alpha-ketoglutarate-dependent dioxygenase alkB homologue 7 CG14798 11-Aug-17 DroID_v2017_08 Drer\alkbh7 - Cele\Y46G5A.35 Xtro\alkbh7 Mmus\Alkbh7 Hsap\ALKBH7 FBgn0036655 CG13031 - http://flybase.org/reports/FBgn0036655 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13031 - CG13031 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0037370 CG1236 - http://flybase.org/reports/FBgn0037370 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR006139 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" - CG1236 "IPR006139:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040:NAD(P)-binding domain, IPR029753:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site" CG1236 11-Aug-17 DroID_v2017_08 "Drer\grhprb, Drer\grhpra, Drer\mthfd2l, Drer\zgc:136493, Drer\mthfd2" "Scer\FDH1, Scer\SER33, Scer\YGL185C, Scer\GOR1, Scer\YPL113C, Scer\SER3" - "Xtro\mthfd2l, Xtro\grhpr.2, Xtro\grhpr.1, Xtro\mthfd2" "Mmus\Mthfd2, Mmus\Mthfd2l, Mmus\Grhpr" "Hsap\GRHPR, Hsap\MTHFD2, Hsap\MTHFD2L" "viable,fertile" FBgn0022362 Pt-9A Adult protein-9A http://flybase.org/reports/FBgn0022362 - gene - - - Pt-9A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035985 Cpr67B Cuticular protein 67B http://flybase.org/reports/FBgn0035985 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model sleep ; GO:0030431 | inferred from expression pattern chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr67B, CG3672" IPR000618:Insect cuticle protein CG3672 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0040331 EY2-6 EY2-6 http://flybase.org/reports/FBgn0040331 gene - - - EY2-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043356 EP2599 EP2599 http://flybase.org/reports/FBgn0043356 gene - - - EP2599 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "trichogen cell,tormogen cell" FBgn0069236 gl(1)83-27 gl(1)83-27 http://flybase.org/reports/FBgn0069236 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(1)83-27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic abdominal segment" FBgn0005357 su(tu-bw) suppressor of tumor-brown http://flybase.org/reports/FBgn0005357 - gene - - - su(tu-bw) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259322 C623 - http://flybase.org/reports/FBgn0259322 gene - - - C623 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing margin,wing vein" FBgn0085201 CG34172 - http://flybase.org/reports/FBgn0085201 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from electronic annotation with InterPro:IPR003177 - mitochondrial respiratory chain ; GO:0005746 | inferred from electronic annotation with InterPro:IPR003177 CG34172 "IPR003177:Cytochrome c oxidase, subunit VIIa" CG34172 11-Aug-17 DroID_v2017_08 "Drer\cox7a3, Drer\cox7a2b, Drer\cox7a2a, Drer\cox7a1" - - - "Mmus\Cox7a2, Mmus\Cox7a1, Mmus\Cox7a2l" "Hsap\COX7A2L, Hsap\COX7A1, Hsap\COX7A2" FBgn0051394 CG31394 - http://flybase.org/reports/FBgn0051394 protein_coding_gene - - - "BcDNA:RE47391, CG31394" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002492 l(3)SG52 lethal (3) SG52 http://flybase.org/reports/FBgn0002492 - gene - - - "l(3)15m-25, l(3)SG52" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0053155 CG33155 - http://flybase.org/reports/FBgn0053155 protein_coding_gene molecular_function ; GO:0003674 | no biological data available larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG33184, BcDNA:GM05817, CR33155, CG33155" - CG33155 11-Aug-17 DroID_v2017_08 Drer\mrpl53 - "Cele\ZK512.11, Cele\mrpl-53" Xtro\mrpl53 Mmus\Mrpl53 Hsap\MRPL53 FBgn0085487 CG34458 - http://flybase.org/reports/FBgn0085487 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 molecular_function ; GO:0003674 | no biological data available" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available "CG34458, CG5197, SP118" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR010916:TonB box, conserved site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG34458 11-Aug-17 DroID_v2017_08 "Drer\cfd, Drer\zgc:163079, Drer\si:dkey-16l2.17, Drer\zgc:92313, Drer\gzmk, Drer\si:ch211-165b19.5, Drer\gzma, Drer\ovch1, Drer\si:dkeyp-93a5.3, Drer\si:ch211-165b19.8, Drer\si:ch211-165b19.9, Drer\zgc:165423, Drer\LOC100004427, Drer\gzm3" - "Cele\try-1, Cele\try-6, Cele\svh-1" Xtro\gzmak "Mmus\Cma2, Mmus\Egfbp2, Mmus\Klk1b16, Mmus\Mcpt9, Mmus\Mcpt8, Mmus\Gzmn, Mmus\Gzmd, Mmus\Klk9, Mmus\Prss55, Mmus\Klk15, Mmus\Klk1b5, Mmus\Klk10, Mmus\Klk1b8" "Hsap\KLK10, Hsap\KLK15, Hsap\KLK9, Hsap\CTSG, Hsap\GZMB, Hsap\KLK12" FBgn0034906 CG13561 - http://flybase.org/reports/FBgn0034906 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13561 IPR010512:Protein of unknown function DUF1091 CG13561 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0037030 CG3288 - http://flybase.org/reports/FBgn0037030 protein_coding_gene - - - CG3288 - CG3288 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016989 ms(3)25 ms(3)25 http://flybase.org/reports/FBgn0016989 - gene - - - ms(3)25 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003901 twl twirl http://flybase.org/reports/FBgn0003901 - gene - - - twl - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" wing FBgn0029085 flc fleece http://flybase.org/reports/FBgn0029085 gene - - - flc - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,recessive" macrochaeta FBgn0062693 EP1246 EP1246 http://flybase.org/reports/FBgn0062693 gene - - - "EP(3)1246, EP1246" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025796 Su(var)501 Suppressor of variegation 501 http://flybase.org/reports/FBgn0025796 - gene - - - "Su-var(2)501, Su(var)501" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082951 snoRNA:Me18S-C1366 snoRNA:Me18S-C1366 http://flybase.org/reports/FBgn0082951 snoRNA_gene - - - "snoRNA:Me18S-C1366, Me18S-Cm1366, Me18S-C1366, CR34532, chr2R:10136644..10136796" - CR34532 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065147 l(3)SH081 lethal (3) SH081 http://flybase.org/reports/FBgn0065147 gene - - - "l(3)SH081, l(2)SH3 081" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002028 l(2)37Bj lethal (2) 37Bj http://flybase.org/reports/FBgn0002028 - gene - - - "Bj, l(2)E35, l(2)37Bj" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044505 BS\gag BS element gag http://flybase.org/reports/FBgn0044505 transposable_element_gene - - - BS\gag - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001239 Hooked-veins Hooked veins http://flybase.org/reports/FBgn0001239 - gene - - - "Hooked-veins, Hv" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" "wing vein,crossvein,eye" FBgn0052266 CG32266 - http://flybase.org/reports/FBgn0052266 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GM24338, CG32266" - CG32266 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260288 GSd492 - http://flybase.org/reports/FBgn0260288 gene - - - GSd492 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003292 rt rotated abdomen http://flybase.org/reports/FBgn0003292 - protein_coding_gene dolichyl-phosphate-mannose-protein mannosyltransferase activity ; GO:0004169 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W5D4 dolichyl-phosphate-mannose-protein mannosyltransferase activity ; GO:0004169 | contributes_to inferred from direct assay "sarcomere organization ; GO:0045214 | inferred from genetic interaction with Dg muscle attachment ; GO:0016203 | inferred from genetic interaction with Dg specification of segmental identity, abdomen ; GO:0007385 | inferred from mutant phenotype lipid glycosylation ; GO:0030259 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype protein O-linked mannosylation ; GO:0035269 | inferred from direct assay muscle organ development ; GO:0007517 | inferred from mutant phenotype regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000006098" endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000006098 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity endoplasmic reticulum ; GO:0005783 | inferred from direct assay "Rot_abd, dPOMT1, pomt, DPOMT1, fs(3)neo1, CG6097, rt, POMT1, roa, dPomt1, Rt" "IPR003342:Glycosyl transferase family 39/83, IPR016093:MIR motif, IPR027005:Glycosyltransferase 39-like, IPR032421:Protein O-mannosyl-transferase, C-terminal four TM domain" CG6097 11-Aug-17 DroID_v2017_08 "Drer\pomt2, Drer\pomt1" "Scer\PMT5, Scer\PMT4, Scer\PMT2, Scer\PMT7, Scer\PMT6, Scer\PMT1, Scer\PMT3" - Xtro\pomt1 "Mmus\Pomt1, Mmus\Pomt2" "Hsap\POMT2, Hsap\POMT1" "female sterile,recessive,visible,male fertile,reduced,female fertile,neurophysiology defective,locomotor behavior defective,flight defective,viable,male sterile,lethal,heat sensitive,short lived" "adult abdomen,adult cuticle,embryonic/larval muscle system,muscle attachment site,sarcomere | third instar larval stage,embryonic/larval somatic muscle,lateral,abdomen" DRSC11391 K -0.05871842 0.207356181 -0.337365076 0.175107412 -1.222954938 -1.944121112 FBgn0031987 CG12375 - http://flybase.org/reports/FBgn0031987 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12375 "IPR001279:Metallo-beta-lactamase, IPR011991:Winged helix-turn-helix DNA-binding domain" CG12375 11-Aug-17 DroID_v2017_08 "Drer\pnkd, Drer\mblac2, Drer\lactb2, Drer\hagh" "Scer\GLO2, Scer\GLO4" Cele\Y53F4B.39 "Xtro\pnkd, Xtro\hagh, Xtro\mblac2, Xtro\lactb2, Xtro\haghl" "Mmus\Lactb2, Mmus\Mblac2, Mmus\Haghl, Mmus\Pnkd, Mmus\Hagh" "Hsap\HAGH, Hsap\PNKD, Hsap\MBLAC2, Hsap\HAGHL, Hsap\LACTB2" viable FBgn0039945 CG17159 - http://flybase.org/reports/FBgn0039945 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG40460, anon-20Ea, CG17159, FBgn0058460" - CG17159 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260644 CG42536 - http://flybase.org/reports/FBgn0260644 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42536 - CG42536 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061131 l(3)S002401b lethal (3) S002401b http://flybase.org/reports/FBgn0061131 gene - - - "0024/01, l(3)S002401b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037670 Ibf1 Insulator binding factor 1 http://flybase.org/reports/FBgn0037670 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Cp190 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay positive regulation of chromatin silencing ; GO:0031937 | inferred from genetic interaction with w nucleus ; GO:0005634 | inferred from direct assay "CG8436, Ibf1" - CG8436 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC16419 E 1.183642657 0.799364511 1.059615955 1.508087089 -1.437248096 -0.765726161 FBgn0040719 CG15357 - http://flybase.org/reports/FBgn0040719 protein_coding_gene - - - CG15357 - CG15357 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0053477 CG33477 - http://flybase.org/reports/FBgn0053477 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33477 IPR010512:Protein of unknown function DUF1091 CG33477 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037416 Osi9 Osiris 9 http://flybase.org/reports/FBgn0037416 protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi9, CG15592" IPR012464:Protein of unknown function DUF1676 CG15592 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010080 Rst(3)mth1 Resistance (3) malathion 1 http://flybase.org/reports/FBgn0010080 - gene - - - Rst(3)mth1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033056 CG7856 - http://flybase.org/reports/FBgn0033056 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG7856 - CG7856 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031157 CG1503 - http://flybase.org/reports/FBgn0031157 protein_coding_gene endopeptidase activity ; GO:0004175 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 SUMO-specific protease activity ; GO:0016929 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 protein desumoylation ; GO:0016926 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 CG1503 "IPR003653:Ulp1 protease family, C-terminal catalytic domain" CG1503 11-Aug-17 DroID_v2017_08 "Drer\senp5, Drer\eif4a1a, Drer\senp2, Drer\senp3b, Drer\senp8, Drer\senp3a" Scer\ULP1 "Cele\K04F10.7, Cele\ulp-2, Cele\ulp-3, Cele\ulp-5" Xtro\senp8 "Mmus\Senp3, Mmus\Senp5, Mmus\Senp8" "Hsap\SENP5, Hsap\SENP3, Hsap\SENP8" viable FBgn0262796 Pgant35A::Hsap\GALNT11 - http://flybase.org/reports/FBgn0262796 engineered_fusion_gene - - - Pgant35A::Hsap\GALNT11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022099 l(2)k07136 lethal (2) k07136 http://flybase.net/reports/FBgn0022099.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0012003 tRNA:Val-CAC-2-5 transfer RNA:Valine-CAC 2-5 http://flybase.org/reports/FBgn0012003 "FBgn0003855, FBgn0011997, FBgn0051214, FBgn0060020" tRNA_gene GUG codon-amino acid adaptor activity ; GO:0033452 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033452 cytosol ; GO:0005829 | inferred by curator from GO:0033452 "valine tRNA, tRNA[Val][[3b]], AE002708.trna41-ValCAC, tRNA:V3b, tRNA:V:CAC:AE002708-c, CR31214, tRNA:val3b:92Ba, chr3R.trna47-ValCAC, tRNA:Val-CAC-2-5, tRNA:V3b:92Ba, tRNA-Val-CAC-2-5, GUG" - CR31214 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015728 Etr1 ETR-1-like http://flybase.org/reports/FBgn0015728 - gene - - - "etr-1, Etr1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015475 l(2)45Ac lethal (2) 45Ac http://flybase.org/reports/FBgn0015475 - gene - - - l(2)45Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028066 l(3)S091014 lethal (3) S091014 http://flybase.org/reports/FBgn0028066 gene - - - "0910/14, l(3)S091014" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037238 CG1090 - http://flybase.org/reports/FBgn0037238 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 sodium ion binding ; GO:0031402 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium, potassium:sodium antiporter activity ; GO:0008273 | inferred from sequence or structural similarity with UniProtKB:Q9U6A0 calcium, potassium:sodium antiporter activity ; GO:0008273 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 potassium ion binding ; GO:0030955 | inferred from biological aspect of ancestor with PANTHER:PTN000090975" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity with UniProtKB:Q9U6A0 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with UniProtKB:Q9U6A0 cellular calcium ion homeostasis ; GO:0006874 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9U6A0 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 CG1090 "IPR004481:Sodium/potassium/calcium exchanger, IPR004837:Sodium/calcium exchanger membrane region" CG1090 11-Aug-17 DroID_v2017_08 "Drer\slc24a2, Drer\slc24a5, Drer\si:ch73-335m24.5, Drer\slc24a1, Drer\slc24a4a, Drer\slc24a4b, Drer\slc24a3" Scer\YDL206W "Cele\ncx-5, Cele\ncx-4" "Xtro\ilkap, Xtro\slc24a4, Xtro\slc24a2, Xtro\slc24a5, Xtro\slc24a3" "Mmus\Slc24a3, Mmus\Slc24a4, Mmus\Slc24a2, Mmus\Slc24a5, Mmus\Slc24a1" "Hsap\SLC24A4, Hsap\SLC24A5, Hsap\SLC24A1, Hsap\SLC24A2, Hsap\SLC24A3" viable FBgn0005473 l(1)ts967 lethal (1) ts967 http://flybase.org/reports/FBgn0005473 - gene - - - l(1)ts967 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" FBgn0267712 CR46045 - http://flybase.org/reports/FBgn0267712 non_protein_coding_gene - - - CR46045 - CR46045 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010184 tu(2)e144 tu(2)e144 http://flybase.org/reports/FBgn0010184 - gene - - - "e144, tu(2)e144" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039120 Nup98-96 Nucleoporin 98-96kD http://flybase.org/reports/FBgn0039120 protein_coding_gene "chromatin DNA binding ; GO:0031490 | inferred from mutant phenotype nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000574450 promoter-specific chromatin binding ; GO:1990841 | inferred from direct assay nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000574450 structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000574450 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P20659 inferred from physical interaction with UniProtKB:Q86BS3,UniProtKB:Q9VGA4,UniProtKB:Q9VP57 inferred from physical interaction with UniProtKB:Q9V3J8 protein binding ; GO:0005515 | inferred from physical interaction with Rae1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VKJ3 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with SGD:S000001551 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000574450" "telomere tethering at nuclear periphery ; GO:0034398 | inferred from biological aspect of ancestor with PANTHER:PTN000574450 positive regulation of gene expression ; GO:0010628 | inferred from genetic interaction with FoxK positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype cellular response to heat ; GO:0034605 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from genetic interaction with UniProtKB:B8A421,UniProtKB:Q9VCH5,UniProtKB:Q9VWW4 inferred from genetic interaction with UniProtKB:B8A421,UniProtKB:Q9VCH5,UniProtKB:Q9W0E9 inferred from genetic interaction with UniProtKB:B8A421,UniProtKB:Q9VCH5,UniProtKB:Q9W0F1 inferred from genetic interaction with UniProtKB:A1YK24,UniProtKB:Q9VCH5,UniProtKB:Q9VWW4 inferred from genetic interaction with UniProtKB:A1YK24,UniProtKB:Q9VCH5,UniProtKB:Q9W0E9 inferred from genetic interaction with UniProtKB:A1YK24,UniProtKB:Q9VCH5,UniProtKB:Q9W0F1 inferred from genetic interaction with UniProtKB:A1YK24,UniProtKB:B8A421,UniProtKB:Q9VWW4 inferred from genetic interaction with UniProtKB:A1YK24,UniProtKB:B8A421,UniProtKB:Q9W0E9 inferred from genetic interaction with UniProtKB:A1YK24,UniProtKB:B8A421,UniProtKB:Q9W0F1 positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype cellular response to ecdysone ; GO:0071390 | inferred from direct assay posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery ; GO:0000973 | inferred from biological aspect of ancestor with PANTHER:PTN000574450 positive regulation of transcription initiation from RNA polymerase II promoter ; GO:0060261 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation by host of viral transcription ; GO:0043922 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000574450 heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from direct assay" nuclear pore ; GO:0005643 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nuclear pore central transport channel ; GO:0044613 | inferred from sequence or structural similarity with SGD:S000001551 nucleus ; GO:0005634 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay inferred from mutant phenotype chromatin ; GO:0000785 | inferred from direct assay inferred from mutant phenotype polytene chromosome ; GO:0005700 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from physical interaction with Rae1 chromatin ; GO:0000785 | inferred from mutant phenotype nuclear pore cytoplasmic filaments ; GO:0044614 | inferred from biological aspect of ancestor with PANTHER:PTN000574450 "Nup96, Nup98-Nup96, CG10198, l(3)95BCd, Nup98/96, CG10201, Nup98, Nup98-96, nup98-96, Nup-98, nup145, Nup 96, Nup 98, NUP98, Nup96-98, Nup" "IPR007230:Peptidase S59, nucleoporin, IPR021967:Nuclear protein 96, IPR025574:Nucleoporin FG repeat" CG10198 11-Aug-17 DroID_v2017_08 "Drer\ncoa5, Drer\nup98, Drer\nup62l, Drer\nup58" "Scer\NUP145, Scer\NSP1, Scer\NUP116, Scer\NUP100, Scer\NUP49" "Cele\npp-10, Cele\npp-11" "Xtro\ncoa5, Xtro\nup98" "Mmus\Nup62, Mmus\Nupl1, Mmus\Nup62cl, Mmus\Ncoa5, Mmus\Nup98" "Hsap\NUP58, Hsap\NUP98, Hsap\NCOA5, Hsap\NUP62" "lethal,recessive,cell growth defective" "male germline cell,male germline stem cell,primary gonial cell,spermatogonium,male fusome,female fusome,nurse cell spectrosome,female germline cell" DRSC14209 EK 1.242735482 0.299723518 -1.603496707 -2.777895182 0.480003666 1.567589113 FBgn0002458 l(3)SG11 lethal (3) SG11 http://flybase.org/reports/FBgn0002458 - gene - - - "l(3)15m-33, l(3)SG11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0265190 PIG-S Phosphatidylinositol glycan anchor biosynthesis class S http://flybase.org/reports/FBgn0265190 protein_coding_gene GPI-anchor transamidase activity ; GO:0003923 | contributes_to inferred from sequence or structural similarity with MGI:MGI:2687325 attachment of GPI anchor to protein ; GO:0016255 | inferred from electronic annotation with InterPro:IPR019540 rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype regulation of Golgi to plasma membrane protein transport ; GO:0042996 | inferred from mutant phenotype GPI-anchor transamidase complex ; GO:0042765 | inferred from electronic annotation with InterPro:IPR019540 nucleoplasm ; GO:0005654 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG6031, CG13644, CG31120, PIG-S, CG44255, sud2" IPR019540:Phosphatidylinositol-glycan biosynthesis class S protein CG44255 11-Aug-17 DroID_v2017_08 "Drer\pigs, Drer\LOC108179092, Drer\ogfod1" "Scer\GPI17, Scer\TPA1" "Cele\hpo-5, Cele\C17G10.1" "Xtro\ogfod1, Xtro\pigs" "Mmus\Ogfod1, Mmus\Pigs" "Hsap\OGFOD1, Hsap\PIGS" lethal - all die before end of embryonic stage "rhabdomere,somatic clone" FBgn0051191 CG31191 - http://flybase.org/reports/FBgn0051191 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 - - "CG17277, CG17276, CG31191" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG31191 11-Aug-17 DroID_v2017_08 - - Cele\F59B8.1 - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0020467 Dsor3 Downstream of raf 3 http://flybase.org/reports/FBgn0020467 - gene - - - Dsor3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265356 tn thin http://flybase.org/reports/FBgn0265356 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:16380 zinc ion binding ; GO:0008270 | inferred from sequence model protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:16380 muscle fiber development ; GO:0048747 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype striated muscle contraction ; GO:0006941 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype Z disc ; GO:0030018 | inferred from direct assay "tn, CG15105, Abba, abba, l(2)tn" "IPR001841:Zinc finger, RING-type, IPR013017:NHL repeat, subgroup, IPR011042:Six-bladed beta-propeller, TolB-like, IPR018957:Zinc finger, C3HC4 RING-type, IPR001258:NHL repeat, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15105 11-Aug-17 DroID_v2017_08 "Drer\trim3b, Drer\LOC100001589, Drer\trim2a, Drer\trim25, Drer\ftr56, Drer\trim3a, Drer\si:ch211-216p19.6, Drer\trim2b, Drer\ftr85, Drer\trim71" "Scer\PSH1, Scer\ASR1" "Cele\nhl-1, Cele\C45G7.4, Cele\ncl-1, Cele\lin-41" Xtro\trim2 "Mmus\Trim25, Mmus\Trim2, Mmus\Trim3, Mmus\Trim71" "Hsap\TRIM25, Hsap\TRIM3, Hsap\TRIM2, Hsap\TRIM71" FBgn0283439 CG46281 - http://flybase.org/reports/FBgn0283439 protein_coding_gene - - - "CG46281, CG12360" - CG46281 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060466 l(3)S113403 lethal (3) S113403 http://flybase.org/reports/FBgn0060466 gene - - - "1134/03, l(3)S113403" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0014360 ms(3)neo6 ms(3)neo6 http://flybase.org/reports/FBgn0014360 - gene - - - ms(3)neo6 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0036905 ms(3)76Ca male sterile (3) 76Ca http://flybase.org/reports/FBgn0036905 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.34, CG14101, ms(3)76Ca" - CG14101 11-Aug-17 DroID_v2017_08 - - "Cele\ZC317.6, Cele\Y53F4B.36, Cele\C09H10.9, Cele\C14C11.1, Cele\C18G1.9" - - - "male sterile,viable,fertile" FBgn0004950 1688-3C 1.688 satellite-related 3C http://flybase.org/reports/FBgn0004950 - repeat_region - - - "1.688, 1688-3C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038394 CG10264 - http://flybase.org/reports/FBgn0038394 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG10264 IPR010562:Haemolymph juvenile hormone binding CG10264 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002418 l(3)DTS6 lethal (3) DTS6 http://flybase.org/reports/FBgn0002418 - gene - - - "DTS-6, l(3)DTS6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal - all die before end of pupal stage,dominant,heat sensitive,some die during pupal stage" FBgn0263740 eIF2gamma eukaryotic translation initiation factor 2 subunit gamma http://flybase.org/reports/FBgn0263740 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000000827" formation of translation preinitiation complex ; GO:0001731 | inferred from sequence or structural similarity with SGD:S000000827 eukaryotic 43S preinitiation complex ; GO:0016282 | inferred from sequence or structural similarity with SGD:S000000827 multi-eIF complex ; GO:0043614 | inferred from sequence or structural similarity with SGD:S000000827 "eIF-2gamma, CG43665, CG6476, eIF-2G, eIF2G, eIF2gamma, 51kDa protein" "IPR000795:Transcription factor, GTP-binding domain, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR015256:Translation initiation factor 2, gamma subunit, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG43665 11-Aug-17 DroID_v2017_08 "Drer\suv39h1a, Drer\ehmt1b, Drer\eif2s3, Drer\suv39h1b" Scer\GCD11 "Cele\set-11, Cele\Y39G10AR.8" "Xtro\suv39h2, Xtro\eif2s3" "Mmus\Suv39h1, Mmus\Ehmt2, Mmus\Eif2s3x, Mmus\Ehmt1, Mmus\Suv39h2, Mmus\Eif2s3y" "Hsap\SUV39H2, Hsap\EHMT1, Hsap\EIF2S3, Hsap\SUV39H1, Hsap\EHMT2" FBgn0023125 anon-10Ai anon-10Ai http://flybase.org/reports/FBgn0023125 - gene - - - "1, anon-10Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265657 CR44464 - http://flybase.org/reports/FBgn0265657 non_protein_coding_gene - - - "lincRNA.324, CR44464" - CR44464 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065643 l(2)SH0755 lethal (2) SH0755 http://flybase.org/reports/FBgn0065643 gene - - - "l(2)SH0755, l(2)SH2 0755" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265626 CG44434 - http://flybase.org/reports/FBgn0265626 protein_coding_gene - - - "CG44434, CG15086" - CG44434 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032140 CG13117 - http://flybase.org/reports/FBgn0032140 protein_coding_gene - - - "BcDNA:SD27505, CG13117" - CG13117 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028911 tRNA:Pro-AGG-1-3 transfer RNA:Proline-AGG 1-3 http://flybase.org/reports/FBgn0028911 tRNA_gene CCU codon-amino acid adaptor activity ; GO:0033421 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033421 cytosol ; GO:0005829 | inferred by curator from GO:0033421 "BG:DS01486.3, tRNA:pro, AE002690.trna14-ProAGG, tRNA:P:AGG:AE002690-d, CR31979, chr2L.trna23-ProAGG, tRNA-Pro-AGG-1-3, tRNA:Pro-AGG-1-3, tRNA:P:35Bb, CCU" - CR31979 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051661 CG31661 - http://flybase.org/reports/FBgn0051661 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 eggshell chorion assembly ; GO:0007306 | inferred from expression pattern inferred from genomic context proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 chorion ; GO:0042600 | inferred from genomic context "CG10872, CG31661" "IPR001461:Aspartic peptidase A1 family, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG31661 11-Aug-17 DroID_v2017_08 "Drer\ctsd, Drer\ren, Drer\nots, Drer\zgc:63831, Drer\zgc:103530" "Scer\YPS1, Scer\YPS5, Scer\YPS3, Scer\YPS7, Scer\YPS6, Scer\PEP4, Scer\YGL258W-A, Scer\BAR1, Scer\MKC7" "Cele\asp-3, Cele\asp-17, Cele\asp-16, Cele\asp-7, Cele\asp-1, Cele\asp-4, Cele\asp-14, Cele\asp-12, Cele\asp-18, Cele\asp-5, Cele\asp-6, Cele\asp-19, Cele\asp-10, Cele\asp-2, Cele\asp-8, Cele\asp-13, Cele\asp-15, Cele\asp-9" "Xtro\pga4, Xtro\ctse, Xtro\bace1, Xtro\bace2, Xtro\pgc, Xtro\LOC496913, Xtro\ctsd, Xtro\napsa, Xtro\ren" "Mmus\Bace1, Mmus\Bace2, Mmus\Napsa, Mmus\Cym, Mmus\Pgc, Mmus\Ctse, Mmus\Ctsd, Mmus\Ren2, Mmus\Ren1, Mmus\Pga5" "Hsap\CTSD, Hsap\NAPSA, Hsap\PGA4, Hsap\CTSE, Hsap\PGA3, Hsap\PGA5, Hsap\PGC, Hsap\REN, Hsap\BACE1, Hsap\BACE2" "viable,visible" trichogen cell FBgn0029707 CG12688 - http://flybase.org/reports/FBgn0029707 protein_coding_gene - - - CG12688 - CG12688 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033933 CG10104 - http://flybase.org/reports/FBgn0033933 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 - CG10104 "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG10104 11-Aug-17 DroID_v2017_08 "Drer\ren, Drer\ctsd, Drer\zgc:63831, Drer\zgc:103530, Drer\nots" "Scer\MKC7, Scer\YPS3, Scer\YPS1, Scer\YGL258W-A, Scer\PEP4, Scer\YPS5, Scer\YPS7, Scer\YPS6, Scer\BAR1" "Cele\asp-6, Cele\asp-4, Cele\asp-7, Cele\asp-9, Cele\asp-13, Cele\asp-16, Cele\asp-2, Cele\asp-17, Cele\asp-3, Cele\asp-8, Cele\asp-15, Cele\asp-12, Cele\asp-19, Cele\asp-1, Cele\asp-10, Cele\asp-14, Cele\asp-5, Cele\asp-18" "Xtro\pgc, Xtro\bace2, Xtro\bace1, Xtro\pga4, Xtro\ctse, Xtro\napsa, Xtro\ctsd, Xtro\ren, Xtro\LOC496913" "Mmus\Cym, Mmus\Bace1, Mmus\Ren1, Mmus\Pgc, Mmus\Bace2, Mmus\Ctse, Mmus\Napsa, Mmus\Ren2, Mmus\Ctsd, Mmus\Pga5" "Hsap\REN, Hsap\BACE2, Hsap\BACE1, Hsap\PGA3, Hsap\PGC, Hsap\CTSE, Hsap\KCTD11, Hsap\PGA4, Hsap\NAPSA, Hsap\PGA5, Hsap\CTSD" viable FBgn0265766 CR44573 - http://flybase.org/reports/FBgn0265766 non_protein_coding_gene - - - CR44573 - CR44573 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035959 CG4911 - http://flybase.org/reports/FBgn0035959 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG4911, FBXO4" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG4911 11-Aug-17 DroID_v2017_08 Drer\fbxo33 - Cele\K02A6.3 "Xtro\fbxo33, Xtro\fbxl21" "Mmus\Fbxl21, Mmus\Fbxo33, Mmus\Fbxo39" "Hsap\FBXO33, Hsap\FBXO39, Hsap\FBXL21" viable FBgn0062529 l(3)88EFc lethal (3) 88EFc http://flybase.org/reports/FBgn0062529 gene - - - l(3)88EFc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0060766 l(3)S062516b lethal (3) S062516b http://flybase.org/reports/FBgn0060766 gene - - - "0625/16, l(3)S062516b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000743 fs(1)A214 female sterile (1) A214 http://flybase.org/reports/FBgn0000743 - gene - - - "fs(1)214, fs(1)A214" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,heat sensitive,mitotic cell cycle defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" blastoderm embryo FBgn0065200 l(2)SH2307 lethal (2) SH2307 http://flybase.org/reports/FBgn0065200 gene - - - "l(2)SH2307, l(2)SH2 2307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262239 mir-961 mir-961 stem loop http://flybase.org/reports/FBgn0262239 miRNA_gene - "regulation of feeding behavior ; GO:0060259 | inferred from genetic interaction with mir-959, mir-960, mir-962 immune response ; GO:0006955 | inferred from genetic interaction with mir-959, mir-960, mir-962" - "dme-mir-961, 961, mir-961, CR42946, miR-961" - CR42946 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030237 CG15209 - http://flybase.org/reports/FBgn0030237 protein_coding_gene - - - "anon-EST:Posey262, BcDNA:SD22308, CG15209" - CG15209 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085505 CR40629 - http://flybase.org/reports/FBgn0085505 non_protein_coding_gene - - - "CR40629, CG40629" - CR40629 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069322 X-162-11 X-162-11 http://flybase.org/reports/FBgn0069322 gene molecular_function ; GO:0003674 | no biological data available trunk segmentation ; GO:0035290 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-162-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8" FBgn0033341 MrgBP MRG/MORF4L binding protein http://flybase.org/reports/FBgn0033341 protein_coding_gene - histone exchange ; GO:0043486 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001783547 neurogenesis ; GO:0022008 | inferred from mutant phenotype NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay "MRGBP, dMrgB, dMrgBP, CG13746, MrgBP" IPR012423:Chromatin modification-related protein Eaf7/MRGBP CG13746 11-Aug-17 DroID_v2017_08 Drer\mrgbp Scer\EAF7 Cele\ZK1127.3 Xtro\mrgbp Mmus\Mrgbp Hsap\MRGBP "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC06417 I -1.711745945 -1.781235958 0.090520897 -1.492752747 -1.403166036 -0.664222511 FBgn0029913 Cht11 Chitinase 11 http://flybase.org/reports/FBgn0029913 protein_coding_gene "chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR001579" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781" - "Cht11, CG3044, DmCht11" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG3044 11-Aug-17 DroID_v2017_08 "Drer\ovgp1, Drer\srl, Drer\chia.1, Drer\chia.2, Drer\si:ch211-226m16.2, Drer\chia.5" Scer\CTS2 "Cele\cht-4, Cele\chil-4, Cele\chil-12, Cele\chil-5, Cele\chil-8, Cele\chil-15, Cele\chil-23, Cele\lmd-5, Cele\chil-11, Cele\chil-16, Cele\T19H5.6, Cele\chil-9, Cele\chil-1, Cele\chil-17, Cele\chil-22, Cele\chil-20, Cele\cht-2, Cele\chil-6, Cele\cht-3, Cele\chil-25, Cele\chil-21, Cele\cht-1, Cele\chil-18, Cele\chil-2, Cele\chil-7, Cele\chil-19, Cele\chil-3, Cele\lmd-4, Cele\chil-24, Cele\chil-13" "Xtro\chit1, Xtro\srl, Xtro\chia, Xtro\LOC548945, Xtro\ctbs" "Mmus\Chil4, Mmus\Chia1, Mmus\Srl, Mmus\Chil3, Mmus\Ctbs, Mmus\Chil6, Mmus\Ovgp1, Mmus\Chit1, Mmus\Chil5, Mmus\Chil1" "Hsap\CHI3L2, Hsap\OVGP1, Hsap\CHIT1, Hsap\CHIA, Hsap\SRL, Hsap\CHI3L1" "partially lethal - majority die,some die during pupal stage,viable,fertile,immune response defective" FBgn0265453 CR44353 - http://flybase.org/reports/FBgn0265453 non_protein_coding_gene - - - CR44353 - CR44353 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084127 LA00287 LA00287 http://flybase.org/reports/FBgn0084127 gene - - - LA00287 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013936 E(nd)195 Enhancer(notchoid)195 http://flybase.org/reports/FBgn0013936 - gene - - - E(nd)195 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262002 CG42820 - http://flybase.org/reports/FBgn0262002 protein_coding_gene - - - "CG42820, CG13394" "IPR031936:Domain of unknown function DUF4771, IPR031935:Domain of unknown function DUF4770" CG42820 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,viable" FBgn0014006 Ask1 Apoptotic signal-regulating kinase 1 http://flybase.org/reports/FBgn0014006 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 MAP kinase kinase kinase activity ; GO:0004709 | inferred from sequence or structural similarity receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from biological aspect of ancestor with PANTHER:PTN000172316 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O46084 MAP kinase kinase kinase activity ; GO:0004709 | inferred from sequence or structural similarity with HGNC:6857" regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from mutant phenotype MAPK cascade ; GO:0000165 | inferred from sequence or structural similarity with HGNC:6857 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity positive regulation of JNK cascade ; GO:0046330 | inferred from direct assay positive regulation of stress-activated MAPK cascade ; GO:0032874 | inferred from mutant phenotype positive regulation of stress-activated MAPK cascade ; GO:0032874 | inferred from direct assay inferred from mutant phenotype activation of MAPKK activity ; GO:0000186 | inferred from sequence or structural similarity with HGNC:6857 protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein kinase complex ; GO:1902911 | inferred from sequence or structural similarity with HGNC:6857 "DASK1, ASK1, DPk92B/ASK1, Ask1, DASK, MEKK5/ASK1, CG4720, dASK, pk92B, dAsk1, Pk92B, D-ASK, dASK1" "IPR025136:Domain of unknown function DUF4071, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR011990:Tetratricopeptide-like helical domain" CG4720 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-1i11.3, Drer\map3k5, Drer\map3k1, Drer\map3k15" "Scer\STE11, Scer\BCK1" Cele\nsy-1 "Xtro\map3k1, Xtro\map3k15, Xtro\map3k5" "Mmus\Map3k5, Mmus\Map3k15, Mmus\Map3k19, Mmus\Map3k6, Mmus\Map3k1" "Hsap\MAP3K5, Hsap\MAP3K6, Hsap\MAP3K1, Hsap\MAP3K15" "body color defective,heat sensitive,viable" "adult thorax,adult cuticle,wing,heat sensitive" DRSC16789 K -1.000865233 0.673898258 0.229869483 0.393084571 -1.575391561 -0.568029705 FBgn0010855 l(3)05088 lethal (3) 05088 http://flybase.org/reports/FBgn0010855 - gene - - - l(3)05088 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266305 CR44970 - http://flybase.org/reports/FBgn0266305 non_protein_coding_gene - - - CR44970 - CR44970 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265664 CR44471 - http://flybase.org/reports/FBgn0265664 non_protein_coding_gene - - - "lincRNA.950, CR44471" - CR44471 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082690 E(ftz)1027 E(ftz)1027 http://flybase.org/reports/FBgn0082690 gene - - - "1027, E(ftz)1027" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027328 l(1)G0024 lethal (1) G0024 http://flybase.org/reports/FBgn0027328 - gene - - - l(1)G0024 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0044865 MMS-2 MMS-2 http://flybase.org/reports/FBgn0044865 gene - - - MMS-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0010346 Mst75Cb Male-specific RNA 75Cb http://flybase.org/reports/FBgn0010346 FBgn0002861 gene - - - "Mst75C, mst-2, mst(3)ag-2, mst(3)ag-15B, Mst75Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020838 l(2)F42 Florida 42 http://flybase.org/reports/FBgn0020838 - gene - - - "l(2)Fla.'42, l(2)F42" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0281846 ato::da - http://flybase.org/reports/FBgn0281846 engineered_fusion_gene - - - "ato::da, Ato-Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266456 CG45081 - http://flybase.org/reports/FBgn0266456 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45081, CG9666-CDS_overlap" - CG45081 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036249 CG11560 - http://flybase.org/reports/FBgn0036249 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 - - CG11560 "IPR026095:Myb/SANT-like DNA-binding domain-containing protein, IPR003656:Zinc finger, BED-type" CG11560 11-Aug-17 DroID_v2017_08 Drer\msantd1 - - - Mmus\Msantd1 Hsap\MSANTD1 viable FBgn0034498 CG16868 - http://flybase.org/reports/FBgn0034498 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG16868 "IPR002035:von Willebrand factor, type A, IPR029151:Periplasmic sensor domain-like" CG16868 11-Aug-17 DroID_v2017_08 "Drer\cacna2d4b, Drer\cachd1, Drer\cacna2d1a, Drer\cacna2d3, Drer\cacna2d4a, Drer\cacna2d2b" - Cele\unc-36 "Xtro\cacna2d1, Xtro\cacna2d4, Xtro\cachd1, Xtro\cacna2d2" "Mmus\Cacna2d4, Mmus\Cacna2d2, Mmus\Cacna2d1, Mmus\Cachd1, Mmus\Cacna2d3" "Hsap\CACNA2D1, Hsap\CACHD1, Hsap\CACNA2D3, Hsap\CACNA2D2, Hsap\CACNA2D4" "viable,visible" trichogen cell FBgn0065109 ppk11 pickpocket 11 http://flybase.org/reports/FBgn0065109 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 "regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype salt aversion ; GO:0035199 | inferred from mutant phenotype sensory perception of salty taste ; GO:0050914 | inferred from mutant phenotype liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 response to salt stress ; GO:0009651 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG34058, PPK11, CG4110, ppk11, Ppk11" "IPR020903:Epithelial sodium channel, conserved site, IPR001873:Epithelial sodium channel" CG34058 11-Aug-17 DroID_v2017_08 "Drer\asic1c, Drer\asic1b, Drer\asic4b, Drer\asic2, Drer\asic1a, Drer\asic4a" - "Cele\acd-2, Cele\acd-3, Cele\del-4, Cele\del-8, Cele\degt-1, Cele\del-7, Cele\unc-105, Cele\flr-1, Cele\acd-1, Cele\delm-1, Cele\acd-4, Cele\del-1, Cele\delm-2, Cele\acd-5" "Xtro\scnn1g, Xtro\scnn1d, Xtro\scnn1a, Xtro\asic1, Xtro\scnn1b, Xtro\asic4, Xtro\asic5" "Mmus\Asic5, Mmus\Scnn1a, Mmus\Scnn1g, Mmus\Asic2, Mmus\Asic1, Mmus\Scnn1b, Mmus\Asic3, Mmus\Asic4" "Hsap\SCNN1G, Hsap\ASIC1, Hsap\ASIC3, Hsap\ASIC2, Hsap\SCNN1A, Hsap\SCNN1B, Hsap\ASIC5, Hsap\ASIC4, Hsap\SCNN1D" "neurophysiology defective,viable,fertile,taste perception defective" "adult tracheal system,terminal organ" FBgn0033654 Sobp Sine oculis-binding protein http://flybase.org/reports/FBgn0033654 protein_coding_gene transcription factor binding ; GO:0008134 | inferred from physical interaction with so compound eye development ; GO:0048749 | inferred from mutant phenotype - "Sbp, CG8991, Sobp" IPR026092:Retinoic acid-induced protein 2/sine oculis-binding protein homologue CG8991 11-Aug-17 DroID_v2017_08 "Drer\sobpb, Drer\zmp:0000001174, Drer\sobpa" - - Xtro\sobp "Mmus\Sobp, Mmus\Rai2" "Hsap\SOBP, Hsap\RAI2" eye FBgn0002395 l(3)93Fb lethal (3) 93Fb http://flybase.org/reports/FBgn0002395 - gene - - - "er15, l(3)er15, l(3)93Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005050 fft fused filament http://flybase.org/reports/FBgn0005050 - gene - - - fft - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,partially" dorsal appendage FBgn0003446 smt small thorax http://flybase.org/reports/FBgn0003446 - gene - - - smt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,reduced,male fertile,female fertile" "adult head,adult thorax,wing" FBgn0060818 l(3)S052713b lethal (3) S052713b http://flybase.org/reports/FBgn0060818 gene - - - "0527/13, l(3)S052713b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0053416 5SrRNA-Psi:CR33416 5SrRNA-Psi:CR33416 http://flybase.org/reports/FBgn0053416 pseudogene_attribute - - - "CR33416, 5SrRNA-Psi:CR33416" - CR33416 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013545 l(2)KE152 lethal (2) KE152 http://flybase.org/reports/FBgn0013545 - gene - - - l(2)KE152 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044090 E(rst)D61 E(rst)D61 http://flybase.org/reports/FBgn0044090 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D61, E(rst)D61" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0053301 CG33301 - http://flybase.org/reports/FBgn0053301 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4791, CG33301" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG33301 11-Aug-17 DroID_v2017_08 - - "Cele\E02C12.6, Cele\C18B10.6, Cele\H06H21.8, Cele\F59B1.10, Cele\dhs-27, Cele\E02C12.10, Cele\C29F7.2, Cele\E02C12.8, Cele\E02C12.9, Cele\F58B4.5, Cele\nhr-246, Cele\Y45G12C.4, Cele\C29F7.1, Cele\F56A4.5, Cele\H37A05.2" - - - FBgn0267480 CR45830 - http://flybase.org/reports/FBgn0267480 non_protein_coding_gene - - - CR45830 - CR45830 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262885 CR43240 - http://flybase.org/reports/FBgn0262885 pseudogene_attribute - - - CR43240 - CR43240 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264400 FCG-B - http://flybase.org/reports/FBgn0264400 gene - - - FCG-B - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0032877 CG2617 - http://flybase.org/reports/FBgn0032877 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "38E.2, CG2617" "IPR001841:Zinc finger, RING-type" CG2617 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-49c17.3, Drer\rnf26, Drer\mgrn1a, Drer\mgrn1b" - "Cele\C11H1.3, Cele\C56A3.4" "Xtro\mgrn1, Xtro\rnf157" "Mmus\Mgrn1, Mmus\Rnf26, Mmus\Rnf157" "Hsap\RNF157, Hsap\MGRN1, Hsap\RNF26" viable FBgn0065148 l(3)SH079 lethal (3) SH079 http://flybase.org/reports/FBgn0065148 gene - - - "l(3)SH079, l(2)SH3 079" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263765 CR43682 - http://flybase.org/reports/FBgn0263765 non_protein_coding_gene - - - "CR43682, lincRNA.147" - CR43682 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267400 CR45762 - http://flybase.org/reports/FBgn0267400 non_protein_coding_gene - - - CR45762 - CR45762 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263895 l(3)B55 - http://flybase.org/reports/FBgn0263895 gene - - - l(3)B55 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0052055 CG32055 - http://flybase.org/reports/FBgn0052055 protein_coding_gene - - - "CG6590, CT20492, CG32055" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG32055 11-Aug-17 DroID_v2017_08 "Drer\chadla, Drer\igfals, Drer\chad, Drer\chadlb, Drer\lrrc15" Scer\CYR1 "Cele\lron-1, Cele\pan-1, Cele\tol-1, Cele\lron-9, Cele\lron-2" "Xtro\LOC100488097, Xtro\chadl" "Mmus\Chadl, Mmus\Chad" "Hsap\IGFALS, Hsap\CHAD, Hsap\CHADL" viable FBgn0002854 Mst25F Male-specific RNA 25F http://flybase.org/reports/FBgn0002854 - gene - - - "mst323, Mst25F" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052283 Drsl3 Drosomycin-like 3 http://flybase.org/reports/FBgn0052283 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs defense response to fungus ; GO:0050832 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro3, CT30310, Dro-3, CG10813, CG32283, Drs-lE, dro3, Drsl3" "IPR003614:Knottin, scorpion toxin-like" CG32283 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially lethal - majority die,some die during pupal stage" FBgn0037506 CG1287 - http://flybase.org/reports/FBgn0037506 protein_coding_gene - - - "BEST:GH03396, CG1287" IPR006214:Bax inhibitor 1-related CG1287 11-Aug-17 DroID_v2017_08 Drer\ghitm - Cele\K11H12.8 Xtro\ghitm Mmus\Ghitm Hsap\GHITM viable FBgn0001999 l(2)36Ac lethal (2) 36Ac http://flybase.org/reports/FBgn0001999 - gene - - - "l(2L)HT-9, l(2)HT-9, l(2)36Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004169 up upheld http://flybase.org/reports/FBgn0004169 "FBgn0001267, FBgn0003955, FBgn0047222" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from direct assay regulation of muscle contraction ; GO:0006937 | inferred from electronic annotation with InterPro:IPR027707 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype cellular calcium ion homeostasis ; GO:0006874 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype skeletal muscle thin filament assembly ; GO:0030240 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern "troponin complex ; GO:0005861 | inferred from electronic annotation with InterPro:IPR001978, InterPro:IPR027707 striated muscle thin filament ; GO:0005865 | inferred from direct assay" "TnT, TpnT, FBgn0004169, upheld2, CG7107, int, wupB, dro TnT, BcDNA:LD08591, up, DmTpnT, Tn-T, tnT, cTNT" "IPR027707:Troponin T, IPR001978:Troponin" CG7107 11-Aug-17 DroID_v2017_08 "Drer\tnnt3b, Drer\tnnt1, Drer\tnnt2c, Drer\tnnt2a, Drer\tnnt3a, Drer\tnnt2e, Drer\tnnt2b, Drer\tnnt2d" - "Cele\tnt-4, Cele\tnt-2, Cele\tni-4, Cele\mup-2, Cele\tnt-3" "Xtro\tnnt1, Xtro\tnnt3, Xtro\tnnt2" "Mmus\Tnnt2, Mmus\Tnnt3, Mmus\Tnnt1" "Hsap\TNNT1, Hsap\TNNT3, Hsap\TNNT2" " embryonic stage | mid & late , adult stage , pupal stage--pharate adult stage " organism

"flightless,recessive,visible,dominant,viable,fertile,jumping defective,developmental rate defective,locomotor behavior defective,semidominant,partially lethal - majority live,lethal" "indirect flight muscle,striated muscle thin filament,Z disc,M band,sarcomere,myofibril,sarcoplasmic reticulum,sarcomere | adult stage,wing,mesothoracic extracoxal depressor muscle 66,flight muscle,myosin filament & indirect flight muscle,striated muscle thin filament & indirect flight muscle,Z disc & indirect flight muscle,pupal cuticle,adult thorax,mitochondrion & flight muscle,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,striated muscle myosin thick filament" FBgn0264838 CR44046 - http://flybase.org/reports/FBgn0264838 non_protein_coding_gene - - - CR44046 - CR44046 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013438 demo defective modalities http://flybase.org/reports/FBgn0013438 - gene - - - demo - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective FBgn0260648 Rrp40 Ribosomal RNA processing 40 http://flybase.org/reports/FBgn0260648 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 "nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription ; GO:0071049 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 nuclear polyadenylation-dependent rRNA catabolic process ; GO:0071035 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' ; GO:0034427 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000467 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 U4 snRNA 3'-end processing ; GO:0034475 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 polyadenylation-dependent snoRNA 3'-end processing ; GO:0071051 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype CUT catabolic process ; GO:0071034 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype nuclear polyadenylation-dependent tRNA catabolic process ; GO:0071038 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay ; GO:0043928 | inferred from biological aspect of ancestor with PANTHER:PTN000481223" cytoplasmic exosome (RNase complex) ; GO:0000177 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000005502 inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay exosome (RNase complex) ; GO:0000178 | inferred from direct assay "Rrp40, dRrp40, CG31938" "IPR012340:Nucleic acid-binding, OB-fold, IPR004088:K Homology domain, type 1, IPR026699:Exosome complex RNA-binding protein 1/RRP40/RRP4" CG31938 11-Aug-17 DroID_v2017_08 "Drer\wu:fc33b09, Drer\exosc3" "Scer\RRP4, Scer\RRP40" Cele\exos-3 Xtro\exosc3 Mmus\Exosc3 Hsap\EXOSC3 DRSC00074 K -0.013193319 -0.228755582 -0.344364553 0.61125006 1.693259307 0.598479521 FBgn0266821 CR45283 - http://flybase.org/reports/FBgn0266821 non_protein_coding_gene - - - CR45283 - CR45283 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034066 CG8397 - http://flybase.org/reports/FBgn0034066 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR013784 actin binding ; GO:0003779 | inferred from sequence or structural similarity - ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN000340832 endomembrane system ; GO:0012505 | inferred from direct assay CG8397 "IPR019008:Domain of unknown function DUF2012, IPR013784:Carbohydrate-binding-like fold" CG8397 11-Aug-17 DroID_v2017_08 "Drer\zgc:195050, Drer\emc7" - Cele\C35D10.1 Xtro\emc7 Mmus\Emc7 Hsap\EMC7 viable FBgn0053443 5SrRNA:CR33443 5SrRNA:CR33443 http://flybase.org/reports/FBgn0053443 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33443, 5SrRNA:CR33443" - CR33443 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000301 ch chubby http://flybase.org/reports/FBgn0000301 - gene - - - ch - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "embryonic/first instar larval cuticle,embryonic/larval midgut" FBgn0028646 aralar1 aralar1 http://flybase.org/reports/FBgn0028646 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProt:Q9UJS0 inferred from sequence or structural similarity with UniProtKB:O75746 L-aspartate transmembrane transporter activity ; GO:0015183 | inferred from biological aspect of ancestor with PANTHER:PTN000640306 L-glutamate transmembrane transporter activity ; GO:0005313 | inferred from biological aspect of ancestor with PANTHER:PTN000640304 transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with UniProt:Q9UJS0 inferred from sequence or structural similarity with UniProtKB:O75746 L-glutamate transmembrane transport ; GO:0089711 | inferred from biological aspect of ancestor with PANTHER:PTN000640304 malate-aspartate shuttle ; GO:0043490 | inferred from biological aspect of ancestor with PANTHER:PTN000640306 wound healing ; GO:0042060 | inferred from mutant phenotype aspartate transport ; GO:0015810 | inferred from biological aspect of ancestor with PANTHER:PTN000640306 mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProt:Q9UJS0 inferred from sequence or structural similarity with UniProtKB:O75746 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProt:Q9UJS0 inferred from sequence or structural similarity with UniProtKB:O75746 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640304 "CG2139, DmAralar, BcDNA:GH07418, aralar1, Aralar, aralar" "IPR002048:EF-hand domain, IPR002067:Mitochondrial carrier protein, IPR011992:EF-hand domain pair, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG2139 11-Aug-17 DroID_v2017_08 "Drer\slc25a18, Drer\zgc:92113, Drer\slc25a12, Drer\slc25a22, Drer\si:dkey-201c1.2, Drer\si:ch73-219d10.1" "Scer\AGC1, Scer\PEF1, Scer\SAL1" "Cele\K02F3.2, Cele\F55G1.5, Cele\F20D1.9, Cele\cal-4" "Xtro\slc25a13, Xtro\slc25a12, Xtro\slc25a22, Xtro\slc25a18" "Mmus\Slc25a12, Mmus\Slc25a18, Mmus\Slc25a13, Mmus\Slc25a22" "Hsap\SLC25A22, Hsap\SLC25A18, Hsap\SLC25A12, Hsap\SLC25A13" FBgn0034289 CG10910 - http://flybase.org/reports/FBgn0034289 protein_coding_gene - - - CG10910 - CG10910 11-Aug-17 DroID_v2017_08 "Drer\cda, Drer\zgc:103586" - "Cele\cdd-2, Cele\C29A12.6, Cele\cdd-1" - "Mmus\Gm15114, Mmus\Cda, Mmus\Maged1, Mmus\Maged2, Mmus\Tro" "Hsap\CDA, Hsap\MAGED4, Hsap\MAGED2, Hsap\MAGED1, Hsap\MAGED4B, Hsap\TRO" viable FBgn0036817 CG6865 - http://flybase.org/reports/FBgn0036817 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP63, CG6865" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG6865 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001114, Drer\zmp:0000001088, Drer\prss56, Drer\zgc:55888, Drer\st14a, Drer\tmprss9" - "Cele\svh-1, Cele\try-1, Cele\try-3" "Xtro\tmprss12, Xtro\LOC733551" "Mmus\Gzmm, Mmus\Prss56, Mmus\St14, Mmus\Acr, Mmus\Tmprss12, Mmus\Tmprss13, Mmus\Gzma" "Hsap\PRSS27, Hsap\TMPRSS13, Hsap\GZMA, Hsap\GZMM, Hsap\ACR, Hsap\TMPRSS12, Hsap\PRSS56, Hsap\ST14" viable DRSC10732 I 1.110804 -1.604757084 -0.149844125 0.270809941 0.527378231 0.70782217 FBgn0011112 l(1)Q73 lethal (1) Q73 http://flybase.org/reports/FBgn0011112 FBgn0010210 gene - - - l(1)Q73 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259670 B0404 - http://flybase.org/reports/FBgn0259670 gene - - - B0404 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein L3,wing,wing vein,arista" FBgn0266217 CR44912 - http://flybase.org/reports/FBgn0266217 non_protein_coding_gene - - - CR44912 - CR44912 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036896 wnd wallenda http://flybase.org/reports/FBgn0036896 protein_coding_gene "MAP kinase kinase kinase activity ; GO:0004709 | inferred from electronic annotation with InterPro:IPR017419 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017419 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN001908122 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 protein kinase activity ; GO:0004672 | non-traceable author statement" protein autophosphorylation ; GO:0046777 | inferred from electronic annotation with InterPro:IPR017419 activation of MAPKK activity ; GO:0000186 | inferred from electronic annotation with InterPro:IPR017419 protein phosphorylation ; GO:0006468 | non-traceable author statement long-term memory ; GO:0007616 | inferred from genetic interaction with hiw sprouting of injured axon ; GO:0048682 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 Golgi organization ; GO:0007030 | inferred from mutant phenotype collateral sprouting of injured axon ; GO:0048674 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype axon ; GO:0030424 | inferred from direct assay intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 "DLK/ZPK, wnd, CG8789, MAPKKK, DLK, Wnd, Wnd/DLK" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017419:Mitogen-activated protein kinase kinase kinase 12/13, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG8789 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-45c16.2, Drer\ripk2, Drer\map3k12, Drer\si:dkey-181f22.4, Drer\zak" - "Cele\sid-3, Cele\dlk-1, Cele\zak-1" "Xtro\gucy2f, Xtro\map3k13, Xtro\map3k12" "Mmus\Map3k12, Mmus\Map3k13, Mmus\Ripk2, Mmus\Zak" "Hsap\MAP3K12, Hsap\MAP3K13, Hsap\RIPK2, Hsap\MAP3K20" "male sterile,neuroanatomy defective,RU486 conditional,lethal - all die before end of embryonic stage,some die during embryonic stage,conditional,viable,fertile" "NMJ bouton,RU486 conditional,neuromuscular junctionunspecified,bouton,dorsal multidendritic neuron ddaC,synapseppk.PG,segmental nerve,conditional" FBgn0259828 ifm(2)RS12 indirect flight muscle (2) RS12 http://flybase.org/reports/FBgn0259828 gene - adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS12 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable indirect flight muscle FBgn0004410 het-rep2 heterochromatic repeat 2 http://flybase.org/reports/FBgn0004410 - repeat_region - - - het-rep2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266263 CR44958 - http://flybase.org/reports/FBgn0266263 non_protein_coding_gene - - - CR44958 - CR44958 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052759 CR32759 - http://flybase.org/reports/FBgn0052759 non_protein_coding_gene - - - CR32759 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013615 l(3)L1233 lethal (3) L1233 http://flybase.org/reports/FBgn0013615 - gene - - - l(3)L1233 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267528 CR45868 - http://flybase.org/reports/FBgn0267528 non_protein_coding_gene - - - CR45868 - CR45868 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053768 CG33768 - http://flybase.org/reports/FBgn0053768 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14458, CG33768" IPR010512:Protein of unknown function DUF1091 CG33768 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0083946 lobo lost boys http://flybase.org/reports/FBgn0083946 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sperm storage ; GO:0046693 | inferred from mutant phenotype flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype motile cilium ; GO:0031514 | inferred from direct assay "CG13661, CG13662, CG34110, lobo" "IPR002931:Transglutaminase-like, IPR033551:Dynein regulatory complex subunit 7" CG34110 11-Aug-17 DroID_v2017_08 Drer\ccdc135 - "Cele\fbxa-202, Cele\F40D4.12, Cele\fbxa-218, Cele\fbxa-183, Cele\fbxa-220, Cele\fbxa-201" Xtro\drc7 Mmus\Drc7 Hsap\DRC7 FBgn0011895 tRNA:Lys-CTT-1-9 transfer RNA:Lysine-CTT 1-9 http://flybase.org/reports/FBgn0011895 "FBgn0003796, FBgn0011886, FBgn0050303, FBgn0060183" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "tRNAlys, tRNA[Lys][[2]], AE002778.trna1-LysCTT, tRNA:K2, tRNA:K:CTT:AE002778-a, CR30303, tRNA:lys2:42Ed, chr2R.trna88-LysCTT, tRNA-Lys-CTT-1-9, tRNA:Lys-CTT-1-9, tRNA:K2:42Ed, AAG" - CR30303 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086217 Gc70 - http://flybase.org/reports/FBgn0086217 gene - - - Gc70 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015457 l(2)37CDb lethal (2) 37CDb http://flybase.org/reports/FBgn0015457 - gene - - - "l(2)E137, l(2)37CDb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052281 CG32281 - http://flybase.org/reports/FBgn0052281 protein_coding_gene tRNA (guanine-N1-)-methyltransferase activity ; GO:0009019 | inferred from electronic annotation with InterPro:IPR025792 tRNA methylation ; GO:0030488 | inferred from electronic annotation with InterPro:IPR025792 sleep ; GO:0030431 | inferred from expression pattern - "CG12032, CG32281" "IPR030382:SAM-dependent methyltransferase TRM5/TYW2-type, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR025792:tRNA (guanine(37)-N(1))-methyltransferase, eukaryotic" CG32281 11-Aug-17 DroID_v2017_08 Drer\trmt5 Scer\TRM5 "Cele\C53A5.17, Cele\C53A5.2, Cele\F40F9.10" Xtro\trmt5 Mmus\Trmt5 Hsap\TRMT5 viable FBgn0003313 sala spalt-adjacent http://flybase.org/reports/FBgn0003313 FBgn0061400 protein_coding_gene - gastrulation ; GO:0007369 | inferred from expression pattern - "CG4922, sal, nsal, BcDNA:RE40068, sala, chr2L:11486634..11486740" - CG4922 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003018 ota2 olfactory trap abnormal 2 http://flybase.org/reports/FBgn0003018 - gene molecular_function ; GO:0003674 | no biological data available chemosensory behavior ; GO:0007635 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ota2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,recessive,chemosensitive behavior defective" FBgn0003655 swa swallow http://flybase.org/reports/FBgn0003655 FBgn0044557 protein_coding_gene dynein complex binding ; GO:0070840 | traceable author statement mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | traceable author statement "regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from genetic interaction with mira bicoid mRNA localization ; GO:0045450 | traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | inferred from genetic interaction with mira pole plasm mRNA localization ; GO:0019094 | inferred from mutant phenotype bicoid mRNA localization ; GO:0045450 | non-traceable author statement" - "sww, fs(1)M44, fs(1)1502, fs(1)m44, fs(1)1497, fs(1)M13C82, fs(1)M11-999, CG3429, anon-WO0140519.70, swa, Swa" - CG3429 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S3 , adult stage | female , embryonic stage | blastoderm , embryonic stage | early , adult stage && oogenesis stage | stage S3-10B , embryonic stage | stage 1-3 " " oocyte | ubiquitous

, egg chamber

, organism

, nurse cell

, organism | ubiquitous

" " oogenesis stage | stage >=S5 , embryonic stage | cycle >=8 , oogenesis stage , embryonic stage | cycle <8 , embryonic stage | stage 12 , oogenesis stage && adult stage | female , embryonic stage | 0-6 hr " " oocyte

,

, ovary

" "viable,fertile,lethal,maternal effect,wild-type,recessive,female sterile,mitotic cell cycle defective" "gastrula embryo,maternal effect,embryonic/first instar larval cuticle,actin filament,stage S10 oocyte,stage S11 oocyte,stage S12 oocyte,stage S13 oocyte,stage S14 oocyte,embryonic head,embryonic abdomen,denticle belt,cleavage nucleus,syncytial blastoderm embryo,stage 5 embryo,larva,anterior,blastoderm embryo,centrosome | embryonic stage,pre-blastoderm embryo,aster,spindle,cell cycle,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,cleavage stage embryo" FBgn0060537 l(3)S100403 lethal (3) S100403 http://flybase.org/reports/FBgn0060537 gene - - - "1004/03, l(3)S100403" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0041754 head-peptide head peptide http://flybase.org/reports/FBgn0041754 gene - - - head-peptide - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033969 CG10202 - http://flybase.org/reports/FBgn0033969 protein_coding_gene "intramolecular transferase activity, phosphotransferases ; GO:0016868 | inferred from electronic annotation with InterPro:IPR005844, InterPro:IPR005846, InterPro:IPR016055" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR005844, InterPro:IPR005845, InterPro:IPR005846, InterPro:IPR016055" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000501326 "anon-WO0140519.148, CG10202" "IPR005844:Alpha-D-phosphohexomutase, alpha/beta/alpha domain I, IPR016055:Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III, IPR005843:Alpha-D-phosphohexomutase, C-terminal, IPR005845:Alpha-D-phosphohexomutase, alpha/beta/alpha domain II, IPR005846:Alpha-D-phosphohexomutase, alpha/beta/alpha domain III" CG10202 11-Aug-17 DroID_v2017_08 "Drer\pgm2, Drer\pgm2l1" Scer\PRM15 Cele\Y43F4B.5 "Xtro\pgm2l1, Xtro\pgm2" "Mmus\Pgm2l1, Mmus\Pgm1" "Hsap\PGM2L1, Hsap\PGM2" viable FBgn0266860 CR45321 - http://flybase.org/reports/FBgn0266860 non_protein_coding_gene - - - CR45321 - CR45321 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260362 GSd472 - http://flybase.org/reports/FBgn0260362 gene - - - GSd472 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0021784 l(3)95BCa lethal (3) 95BCa http://flybase.org/reports/FBgn0021784 - gene - - - l(3)95BCa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011198 l(1)304-68 lethal (1) 304-68 http://flybase.org/reports/FBgn0011198 FBgn0010203 gene - - - "304-68, l(1)304-68" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039978 CG17455 - http://flybase.org/reports/FBgn0039978 protein_coding_gene - - - CG17455 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050409 CR30409 - http://flybase.org/reports/FBgn0050409 pseudogene_attribute - - - "CG9872, CG30409, CR30409" IPR032062:Protein of unknown function DUF4803 CR30409 11-Aug-17 DroID_v2017_08 Drer\rpia Scer\RKI1 - Xtro\rpia Mmus\Rpia Hsap\RPIA "viable,fertile" FBgn0031948 CG7149 - http://flybase.org/reports/FBgn0031948 protein_coding_gene "phosphotransferase activity, for other substituted phosphate groups ; GO:0016780 | inferred from electronic annotation with InterPro:IPR000462" phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR000462 phagocytosis ; GO:0006909 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000462 "CG7149, cpt, dCCS3" "IPR000462:CDP-alcohol phosphatidyltransferase, IPR014472:Choline/ethanolamine phosphotransferase" CG7149 11-Aug-17 DroID_v2017_08 "Drer\cept1b, Drer\chpt1, Drer\cept1a, Drer\si:ch211-197l9.4" "Scer\EPT1, Scer\CPT1" "Cele\F54D7.2, Cele\cept-2, Cele\cept-1" "Xtro\LOC100145789, Xtro\chpt1, Xtro\ept1, Xtro\cept1" "Mmus\Cept1, Mmus\Selenoi, Mmus\Chpt1" "Hsap\CEPT1, Hsap\SELENOI, Hsap\CHPT1" "viable,fertile" FBgn0016806 l(1)K8 lethal (1) K8 http://flybase.org/reports/FBgn0016806 - gene - - - "l(1)K8, K8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262034 CG42845 - http://flybase.org/reports/FBgn0262034 protein_coding_gene - - - "CG42845, Chr2L_9349524_9350014.0" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260040 siren4 siren 4 http://flybase.org/reports/FBgn0260040 gene - - - siren4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0052691 CG32691 - http://flybase.org/reports/FBgn0052691 protein_coding_gene - - - CG32691 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052425 CG32425 - http://flybase.org/reports/FBgn0052425 protein_coding_gene - - - "CG5100, CG15869, CG32425" "IPR000008:C2 domain, IPR009009:RlpA-like protein, double-psi beta-barrel domain" CG32425 11-Aug-17 DroID_v2017_08 Drer\c2cd3 - - Xtro\c2cd3 Mmus\C2cd3 Hsap\C2CD3 "viable,fertile" FBgn0259922 Skadu Skadu http://flybase.org/reports/FBgn0259922 protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with Su(var)205 chromosome organization ; GO:0051276 | inferred from sequence or structural similarity with Su(var)205 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008251 chromatin ; GO:0000785 | inferred from sequence or structural similarity with Su(var)205 "Skadu, CG42448, SKADU" "IPR016197:Chromo domain-like, IPR008251:Chromo shadow domain" CG42448 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033446 CG1648 - http://flybase.org/reports/FBgn0033446 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay CG1648 - CG1648 11-Aug-17 DroID_v2017_08 "Drer\si:rp71-61h23.4, Drer\zgc:162150, Drer\plin2" - - "Xtro\plin2, Xtro\plin1, Xtro\plin3" "Mmus\Plin5, Mmus\Plin3, Mmus\Plin2" "Hsap\PLIN3, Hsap\PLIN1, Hsap\PLIN5, Hsap\ADIRF, Hsap\PLIN2" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0283456 EC3-9 Enhancer of CCT 3-9 http://flybase.org/reports/FBgn0283456 gene - - - EC3-9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283658 muc midline uncoordinated http://flybase.org/reports/FBgn0283658 protein_coding_gene dihydrolipoyllysine-residue acetyltransferase activity ; GO:0004742 | inferred from sequence or structural similarity with UniProtKB:P10515 grooming behavior ; GO:0007625 | inferred from mutant phenotype acetyl-CoA biosynthetic process from pyruvate ; GO:0006086 | inferred from sequence or structural similarity with UniProtKB:P10515 lipid particle ; GO:0005811 | inferred from direct assay mitochondrial pyruvate dehydrogenase complex ; GO:0005967 | inferred from sequence or structural similarity with UniProtKB:P10515 "muc, CG5261, EP(2)0816, EP816, anon-WO0118547.121, DLAT" "IPR000089:Biotin/lipoyl attachment, IPR001078:2-oxoacid dehydrogenase acyltransferase, catalytic domain, IPR003016:2-oxo acid dehydrogenase, lipoyl-binding site, IPR006257:Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, IPR011053:Single hybrid motif, IPR004167:E3-binding domain" CG5261 11-Aug-17 DroID_v2017_08 "Drer\dlat, Drer\pdhx" "Scer\LAT1, Scer\PDX1" "Cele\dlat-1, Cele\C30H6.7" "Xtro\pdhx, Xtro\dlat" "Mmus\Pdhx, Mmus\Dlat" "Hsap\DLAT, Hsap\PDHX" wild-type "wing,posterior compartment" FBgn0045478 Gr64b Gustatory receptor 64b http://flybase.org/reports/FBgn0045478 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype taste receptor activity ; GO:0008527 | non-traceable author statement "detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from electronic annotation with InterPro:IPR009318 sensory perception of sweet taste ; GO:0050916 | inferred from genetic interaction with Gr64d, Gr64e, Gr64c, Gr64a, Gr64f sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009318 integral component of membrane ; GO:0016021 | non-traceable author statement "CG14986, CG32257, anon-WO0118547.604, Gr64b, Dmel64b, Gr64, GR64b" IPR009318:Gustatory receptor CG32257 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,viable" FBgn0267045 CG45489 - http://flybase.org/reports/FBgn0267045 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45489 - CG45489 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002832 ms(2)E11 male sterile (2) E11 http://flybase.org/reports/FBgn0002832 - gene - - - "ms2.11, ms(2)2.11, ms(2)E11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0002538 Lcp7 Larval cuticle protein 7 http://flybase.org/reports/FBgn0002538 - gene - - - "LCP7, Lcp7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261020 wol wollknaeuel http://flybase.org/reports/FBgn0261020 protein_coding_gene transferase activity ; GO:0016740 | inferred from biological aspect of ancestor with PANTHER:PTN000092353 Golgi organization ; GO:0007030 | inferred from mutant phenotype protein N-linked glycosylation ; GO:0006487 | inferred from genetic interaction with UniProtKB:P40350 protein O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype protein N-linked glycosylation ; GO:0006487 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype plasma membrane organization ; GO:0007009 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000092356 "wol, CG7870, ALG5, alg5, dAlg5, Wol" "IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG7870 11-Aug-17 DroID_v2017_08 "Drer\ldlra, Drer\alg5" Scer\ALG5 Cele\H43I07.3 Xtro\alg5 "Mmus\Alg5, Mmus\B3gntl1" "Hsap\ALG5, Hsap\B3GNTL1" FBgn0037539 CG10435 - http://flybase.org/reports/FBgn0037539 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN001815042 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from biological aspect of ancestor with PANTHER:PTN001815042 ESCRT I complex ; GO:0000813 | inferred from biological aspect of ancestor with PANTHER:PTN001815042 CG10435 "IPR009060:UBA-like, IPR023340:UMA domain, IPR015940:Ubiquitin-associated domain" CG10435 11-Aug-17 DroID_v2017_08 "Drer\ubap1la, Drer\ubap1lb, Drer\ubap1" - - Xtro\ubap1 "Mmus\Ubap1, Mmus\Ubap1l" "Hsap\UBAP1L, Hsap\UBAP1" "viable,fertile,visible" "heart primordium,trichogen cell" DRSC25312 K 0.154923221 0.417020159 1.184724224 -0.620809161 -0.709173166 -2.020362448 FBgn0029659 CG16782 - http://flybase.org/reports/FBgn0029659 protein_coding_gene - - - CG16782 IPR032007:Protein of unknown function DUF4791 CG16782 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0264487 CG43895 - http://flybase.org/reports/FBgn0264487 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43895 - CG43895 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065677 l(2)SH0674 lethal (2) SH0674 http://flybase.org/reports/FBgn0065677 gene - - - "l(2)SH0674, l(2)SH2 0674" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029761 SK small conductance calcium-activated potassium channel http://flybase.org/reports/FBgn0029761 protein_coding_gene photoreceptor activity ; GO:0009881 | inferred from direct assay calmodulin binding ; GO:0005516 | inferred from biological aspect of ancestor with PANTHER:PTN000016263 small conductance calcium-activated potassium channel activity ; GO:0016286 | inferred from direct assay small conductance calcium-activated potassium channel activity ; GO:0016286 | inferred from sequence or structural similarity with UniProtKB:P70604 potassium ion transport ; GO:0006813 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from sequence or structural similarity with UniProtKB:P70604 regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000016263 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:P70604 integral component of membrane ; GO:0016021 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000016263 "dSK, CG4179, CG12733, CG10706, BcDNA:GM01744, SK, Sk" "IPR015449:Potassium channel, calcium-activated, SK, IPR004178:Calmodulin-binding domain, IPR013099:Potassium channel domain" CG10706 11-Aug-17 DroID_v2017_08 "Drer\kcnn1b, Drer\kcnn3, Drer\kcnn4, Drer\kcnn1a, Drer\si:dkey-76p7.5" - "Cele\kcnl-1, Cele\kcnl-4, Cele\kcnl-3, Cele\kcnl-2" "Xtro\kcnn2, Xtro\kcnn1" "Mmus\Kcnn1, Mmus\Kcnn2, Mmus\Kcnn3, Mmus\Kcnn4" "Hsap\KCNN2, Hsap\KCNN4, Hsap\KCNN3, Hsap\KCNN1" "viable,fertile,immune response defective,neurophysiology defective" photoreceptor cell FBgn0005337 Pub Pub http://flybase.org/reports/FBgn0005337 - gene - - - Pub - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,ommatidium" FBgn0050323 CG30323 - http://flybase.org/reports/FBgn0050323 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - CG30323 "IPR009003:Peptidase S1, PA clan, IPR001254:Serine proteases, trypsin domain" CG30323 11-Aug-17 DroID_v2017_08 - - - Xtro\tpsab1 - - viable FBgn0034157 resilin resilin http://flybase.org/reports/FBgn0034157 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | non-traceable author statement chitin binding ; GO:0008061 | inferred from direct assay extracellular matrix constituent conferring elasticity ; GO:0030023 | inferred from direct assay extracellular matrix constituent conferring elasticity ; GO:0030023 | non-traceable author statement chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular region ; GO:0005576 | non-traceable author statement extracellular matrix ; GO:0031012 | inferred from sequence model protein-carbohydrate complex ; GO:0032992 | inferred from direct assay "CG15920, resilin" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG15920 11-Aug-17 DroID_v2017_08 - - Cele\pqn-29 - - - FBgn0267917 CR46198 - http://flybase.org/reports/FBgn0267917 non_protein_coding_gene - - - "CR46198, lincRNA.439" - CR46198 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011331 l(3)j2C4 lethal (3) j2C4 http://flybase.org/reports/FBgn0011331 - gene - - - l(3)j2C4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029718 mRpL30 mitochondrial ribosomal protein L30 http://flybase.org/reports/FBgn0029718 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AA772463 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AA772463 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AA772463 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "L30, CG7038, mRpL30, mRPL30" "IPR016082:Ribosomal protein L30, ferredoxin-like fold domain, IPR005996:Ribosomal protein L30, bacterial-type" CG7038 11-Aug-17 DroID_v2017_08 Drer\mrpl30 Scer\MRPL33 Cele\mrpl-30 Xtro\mrpl30 Mmus\Mrpl30 "Hsap\MRPL30, Hsap\C2orf15" "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell DRSC18416 K -1.245690207 -0.53606951 -0.441663212 -1.089366861 1.218389331 2.641198684 FBgn0065841 l(2)SH0324 lethal (2) SH0324 http://flybase.org/reports/FBgn0065841 gene - - - l(2)SH0324 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040643 CG12566 - http://flybase.org/reports/FBgn0040643 protein_coding_gene - - - CG12566 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065819 l(2)SH0373 lethal (2) SH0373 http://flybase.org/reports/FBgn0065819 gene - - - "l(2)SH0373, l(2)SH2 0373" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265869 CR44658 - http://flybase.org/reports/FBgn0265869 non_protein_coding_gene - - - "lincRNA.994, CR44658" - CR44658 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043591 E(ro[DOM])50 E(ro[DOM])50 http://flybase.org/reports/FBgn0043591 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available E(ro[DOM])50 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0029885 CG3224 - http://flybase.org/reports/FBgn0029885 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003604 ribosomal large subunit binding ; GO:0043023 | inferred from biological aspect of ancestor with PANTHER:PTN000466553 neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal large subunit export from nucleus ; GO:0000055 | inferred from biological aspect of ancestor with PANTHER:PTN000466553 "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000466553" CG3224 "IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013087:Zinc finger C2H2-type, IPR022755:Zinc finger, double-stranded RNA binding" CG3224 11-Aug-17 DroID_v2017_08 Drer\znf593 Scer\BUD20 Cele\Y56A3A.18 Xtro\znf593 Mmus\Zfp593 Hsap\ZNF593 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0052525 tRNA:Tyr-GTA-2-1 transfer RNA:Tyrosine-GTA 2-1 http://flybase.org/reports/FBgn0052525 tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "AE002620.trna4-TyrGTA, tRNA[Tyr][[1gamma]], tRNA:tyr1:19F, tRNA:Y1:19F, tRNA:Y:GTA:AE002620-b, CR32525, chrX.trna17-TyrGTA, tRNA:Tyr-GTA-2-1, tRNA:CR32525, tRNA-Tyr-GTA-2-1, UAC" - CR32525 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264362 CG43814 - http://flybase.org/reports/FBgn0264362 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43814 - CG43814 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065523 l(2)SH1124 lethal (2) SH1124 http://flybase.org/reports/FBgn0065523 gene - - - "l(2)SH1124, l(2)SH2 1124" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022401 Gase1 Gastric serine protease 1 http://flybase.org/reports/FBgn0022401 - gene - - - Gase1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259751 ms(3)Z3741 - http://flybase.org/reports/FBgn0259751 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "127-109, 168-112, ms(3)Z3741, ms(3)168-112, ms(3)127-109" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable" "Y chromosome loop,Nebenkern,spermatid,nucleus & spermatid,aster" FBgn0266888 CR45349 - http://flybase.org/reports/FBgn0266888 non_protein_coding_gene - - - CR45349 - CR45349 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040022 Set1 SET domain containing 1 http://flybase.org/reports/FBgn0040022 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | inferred from mutant phenotype histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | inferred from direct assay histone H3-K4 dimethylation ; GO:0044648 | inferred from direct assay histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype histone H3-K4 trimethylation ; GO:0080182 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype histone H3-K4 trimethylation ; GO:0080182 | inferred from direct assay Set1C/COMPASS complex ; GO:0048188 | inferred from direct assay euchromatin ; GO:0000791 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay "SET1, aaf45425 Dm, CG17396, CG17395, CG40351, dSet1, l(3)h5, set1, Set1, dSET1, dset1" "IPR000504:RNA recognition motif domain, IPR024657:COMPASS complex Set1 subunit, N-SET domain, IPR001214:SET domain, IPR003616:Post-SET domain" CG40351 11-Aug-17 DroID_v2017_08 "Drer\phf20b, Drer\kmt2d, Drer\kmt2cb, Drer\ash1l, Drer\whsc1l1, Drer\kmt2ca, Drer\nsd1b, Drer\setd1bb, Drer\setd1ba, Drer\phf3, Drer\phf20l1, Drer\setd1a, Drer\kmt2e, Drer\whsc1" "Scer\SET3, Scer\BYE1, Scer\SET4, Scer\SET1, Scer\SET2, Scer\CTI6" "Cele\set-12, Cele\set-2, Cele\C16A11.4, Cele\set-8, Cele\mes-4, Cele\set-26, Cele\lin-59, Cele\set-5, Cele\set-16, Cele\met-1, Cele\set-9" "Xtro\setd1b, Xtro\setd1a" "Mmus\Phf3, Mmus\Dido1, Mmus\Ash1l, Mmus\Setd2, Mmus\Setd1b, Mmus\Nsd1, Mmus\Phf20l1, Mmus\Spocd1, Mmus\Setd1a, Mmus\Whsc1, Mmus\Kmt2c, Mmus\Kmt2d, Mmus\Kmt2e, Mmus\Setd5, Mmus\Whsc1l1" "Hsap\KMT2D, Hsap\WHSC1L1, Hsap\DIDO1, Hsap\SETD2, Hsap\SETD1B, Hsap\ASH1L, Hsap\PHF20, Hsap\KMT2E, Hsap\NSD1, Hsap\SETD1A, Hsap\WHSC1, Hsap\PHF20L1, Hsap\KMT2C, Hsap\SETD5" "viable,lethal - all die before end of pupal stage,some die during pupal stage,lethal,visible" trichogen cell DRSC20930 E -0.9257417 -1.246128966 -1.742146401 -0.132087904 FBgn0025874 Meics Meiotic central spindle http://flybase.org/reports/FBgn0025874 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - cytoplasm ; GO:0005737 | inferred from direct assay spindle microtubule ; GO:0005876 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG8474, Meics" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8474 11-Aug-17 DroID_v2017_08 "Drer\LOC798048, Drer\znf1124, Drer\zgc:171901, Drer\si:ch211-202h22.10, Drer\znf1068, Drer\zgc:113343, Drer\zgc:174646, Drer\zgc:173705, Drer\zgc:113209, Drer\si:ch211-191d2.2, Drer\LOC100534908, Drer\znf989, Drer\zgc:113135, Drer\si:ch211-142b24.6, Drer\LOC100537450, Drer\znf1041, Drer\zgc:174315, Drer\zgc:174624, Drer\zgc:171673, Drer\im:7141269, Drer\znf1069, Drer\znf1059, Drer\zgc:173575, Drer\znf1004, Drer\znf1043, Drer\patz1, Drer\si:dkey-14d8.1, Drer\znf1079, Drer\LOC100329723, Drer\si:ch211-226o13.2, Drer\zgc:113119, Drer\znf1078, Drer\zgc:171727, Drer\zgc:175107, Drer\zgc:171551, Drer\znf569l" "Scer\AZF1, Scer\PZF1" "Cele\fezf-1, Cele\M03D4.4, Cele\Y55F3AM.14, Cele\eor-1, Cele\pag-3, Cele\zfp-2, Cele\hinf-1, Cele\lin-29, Cele\Y5F2A.4, Cele\sdz-12, Cele\blmp-1" Xtro\plag1 "Mmus\Plagl2, Mmus\Zfp879, Mmus\Zfp668, Mmus\Zfp90, Mmus\LOC102632383, Mmus\Zfp40, Mmus\Zfp619, Mmus\Patz1, Mmus\Zfp52, Mmus\Zfp872, Mmus\Zfp719, Mmus\Zfp458, Mmus\Zfp317, Mmus\Zfp729a, Mmus\Zfp27, Mmus\Zfp791, Mmus\Zfp26" "Hsap\ZNF677, Hsap\ZNF141, Hsap\ZNF229, Hsap\ZNF716, Hsap\PATZ1, Hsap\ZNF429, Hsap\ZNF668, Hsap\ZNF596, Hsap\ZNF263, Hsap\ZNF214, Hsap\ZNF266, Hsap\ZNF273, Hsap\ZNF672" DRSC29541 K -0.434256174 -1.204638876 0.274886343 -0.369815417 -1.784835121 -0.135515699 FBgn0005763 l(1)TK410 lethal (1) TK410 http://flybase.org/reports/FBgn0005763 - gene - - - "l410, l(1)TK410" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0024197 quag quagmire http://flybase.org/reports/FBgn0024197 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "l(3)05089, quag" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect,partially lethal - majority die" "embryonic/first instar larval cuticle,maternal effect" FBgn0015964 l(2)46DEb lethal (2) 46DEb http://flybase.org/reports/FBgn0015964 - gene - - - "group 6, l(2)46DEb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002549 lgh longhaired http://flybase.org/reports/FBgn0002549 - gene - - - lgh - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,visible,viable,male,poor,body color defective" "adult head,adult thorax,microchaeta,macrochaeta,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7" FBgn0084037 CG41477 - http://flybase.org/reports/FBgn0084037 protein_coding_gene - - - CG41477 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019780 l(1)29 lethal (1) 29 http://flybase.org/reports/FBgn0019780 - gene - - - l(1)29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010409 RpL18A Ribosomal protein L18A http://flybase.org/reports/FBgn0010409 FBgn0025284 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR021138, InterPro:IPR023573 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR021138, InterPro:IPR023573 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR021138, InterPro:IPR023573 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "L18A, L18, L18a, anon-EST:Posey75, RpL18a, CG6510, RpL18A, RPL18a" "IPR023573:Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A, IPR028877:50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a, IPR021138:60S ribosomal protein L18a/ L20, eukaryotes" CG6510 11-Aug-17 DroID_v2017_08 Drer\rpl18a "Scer\RPL20B, Scer\RPL20A" Cele\rpl-20 Xtro\rpl18a Mmus\Rpl18a Hsap\RPL18A DRSC07538 IEK -2.134900736 -1.493940415 -2.891120101 -5.031504533 1.905558227 3.264631192 FBgn0029888 ND-ASHI NADH dehydrogenase (ubiquinone) ASHI subunit http://flybase.org/reports/FBgn0029888 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR008699, InterPro:IPR016551 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95169" "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95169" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN001401346 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95169 "CG3192, NIAM, ND-ASHI" "IPR008699:NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, IPR016551:NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa" CG3192 11-Aug-17 DroID_v2017_08 Drer\ndufb8 - "Cele\Y51H1A.3, Cele\F47B7.2" Xtro\ndufb8 Mmus\Ndufb8 Hsap\NDUFB8 "viable,visible" trichogen cell FBgn0036870 CG14095 - http://flybase.org/reports/FBgn0036870 protein_coding_gene - - - CG14095 - CG14095 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002267 l(3)69Af lethal (3) 69Af http://flybase.org/reports/FBgn0002267 - gene - - - "rsg29, l(3)rsg29, l(3)69Af" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005509 l(2)24EFg lethal (2) 24EFg http://flybase.org/reports/FBgn0005509 - gene - - - "l(2)Gr.VII, l(2)24EFg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263110 CG43367 - http://flybase.org/reports/FBgn0263110 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000348578 "CG43367, CG1308, CG1295, CG1332" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR011993:PH domain-like, IPR011989:Armadillo-like helical, IPR000409:BEACH domain, IPR023362:PH-BEACH domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR031570:Domain of unknown function DUF4704" CG43367 11-Aug-17 DroID_v2017_08 "Drer\nbeaa, Drer\nsmaf, Drer\nbeal1, Drer\lrba, Drer\nbeal2, Drer\wdfy3, Drer\wdfy4, Drer\nbeab, Drer\wdr81" Scer\BPH1 Cele\sel-2 "Xtro\nbea, Xtro\wdfy3, Xtro\nbeal1, Xtro\nbeal2, Xtro\lyst, Xtro\nsmaf" "Mmus\Nbeal2, Mmus\Nbeal1, Mmus\Wdfy4, Mmus\Nbea, Mmus\Wdr81, Mmus\Nsmaf, Mmus\Lrba, Mmus\Lyst, Mmus\Wdfy3" "Hsap\NBEAL2, Hsap\NSMAF, Hsap\WDFY4, Hsap\WDFY3, Hsap\NBEA, Hsap\LRBA, Hsap\LYST, Hsap\WDR81, Hsap\NBEAL1" FBgn0060639 l(3)S084305b lethal (3) S084305b http://flybase.org/reports/FBgn0060639 gene - - - "0843/05, l(3)S084305b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041126 l(2)45Ak lethal (2) 45Ak http://flybase.org/reports/FBgn0041126 gene - - - l(2)45Ak - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0043577 PGRP-SB2 Peptidoglycan recognition protein SB2 http://flybase.org/reports/FBgn0043577 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | inferred from sequence or structural similarity with PGRP-SC1b innate immune response ; GO:0045087 | inferred from electronic annotation with InterPro:IPR017331 innate immune response ; GO:0045087 | non-traceable author statement peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement peptidoglycan catabolic process ; GO:0009253 | inferred from sequence or structural similarity with PGRP-SC1b immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 extracellular region ; GO:0005576 | inferred from sequence or structural similarity "CG9697, PGRP-SB2, PGRP-SB" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR017331:Peptidoglycan recognition protein, PGRP-S" CG9697 11-Aug-17 DroID_v2017_08 "Drer\pglyrp6, Drer\pglyrp5, Drer\pglyrp2" - - "Xtro\pglyrp1, Xtro\pglyrp1, Xtro\pglyrp2" "Mmus\Pglyrp3, Mmus\Pglyrp1, Mmus\Pglyrp2, Mmus\Pglyrp4" "Hsap\PGLYRP2, Hsap\PGLYRP3, Hsap\PGLYRP4, Hsap\PGLYRP1" "partially lethal - majority die,some die during pupal stage" FBgn0037850 CG14695 - http://flybase.org/reports/FBgn0037850 protein_coding_gene - - - CG14695 - CG14695 11-Aug-17 DroID_v2017_08 "Drer\dnajc10, Drer\pdia6, Drer\erp27, Drer\txndc16, Drer\txndc5" "Scer\EPS1, Scer\MPD2, Scer\MPD1" - "Xtro\txndc16, Xtro\txndc5, Xtro\pdia6" "Mmus\Pdia6, Mmus\Pdia5, Mmus\Txndc5, Mmus\Txndc16, Mmus\Erp27, Mmus\Dnajc10" "Hsap\TXNDC5, Hsap\PDILT, Hsap\PDIA5, Hsap\TXNDC16, Hsap\PDIA6, Hsap\ERP27, Hsap\DNAJC10" "viable,fertile" FBgn0260226 CG42500 - http://flybase.org/reports/FBgn0260226 protein_coding_gene - - - "CG42500, CG14359" IPR013172:Immune-induced protein Dim CG42500 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030070 CG3898 - http://flybase.org/reports/FBgn0030070 protein_coding_gene - - - CG3898 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014934 anon-87Ec anon-87Ec http://flybase.org/reports/FBgn0014934 - gene - - - "C, anon-87Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003885 alphaTub84D alpha-Tubulin at 84D http://flybase.org/reports/FBgn0003885 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002452, InterPro:IPR008280, InterPro:IPR017975 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002452 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002452, InterPro:IPR017975 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype" "microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002452, InterPro:IPR017975 perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay microtubule ; GO:0005874 | inferred from sequence or structural similarity lipid particle ; GO:0005811 | inferred from direct assay neuromuscular junction ; GO:0031594 | microtubule ; GO:0005874 |" "Tub, alpha-tubulin, alpha-Tub, alphaTUB, CG2512, ALPHA 84D, D.m.ALPHA-84D, alpha3, aTub84D, T, 3t, alpha84D, DTA4, alphaTub84D, alphaTub3, alpha3t, alpha-Tub84D, alphaTub, alphaTub84, alpha-tub84D, alphaTUB84D, alpha-tub, Tub1A" "IPR000217:Tubulin, IPR002452:Alpha tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain" CG2512 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-199e17.1, Drer\tuba4l, Drer\tuba7l, Drer\tuba1c, Drer\tuba8l, Drer\tuba2, Drer\tuba1b, Drer\tuba8l4, Drer\tuba1a, Drer\tuba8l2, Drer\tuba8l3, Drer\si:ch211-114n24.6" "Scer\TUB1, Scer\TUB3" "Cele\tba-9, Cele\tba-6, Cele\tba-7, Cele\tba-1, Cele\mec-12, Cele\tba-2, Cele\tba-8, Cele\tba-5, Cele\tba-4" "Xtro\tuba8, Xtro\tuba1a, Xtro\tuba4b, Xtro\tuba3e, Xtro\tuba1c, Xtro\tuba1b, Xtro\tuba4a, Xtro\tuba4, Xtro\tubal3, Xtro\tuba3c" "Mmus\Tuba3b, Mmus\Tuba8, Mmus\Tubal3, Mmus\Tuba3a, Mmus\Tuba4a, Mmus\Tuba1b, Mmus\Tuba1a, Mmus\Tuba1c" "Hsap\TUBA4A, Hsap\TUBA1B, Hsap\TUBA3D, Hsap\TUBA1C, Hsap\TUBA3E, Hsap\TUBA3C, Hsap\TUBA1A, Hsap\TUBAL3, Hsap\TUBA8" " pupal stage , embryonic stage | 6-12 hr , larval stage | second instar , embryonic stage | 2-18 hr , prepupal stage , embryonic stage | 0-3 hr , larval stage | first instar , oogenesis stage && adult stage | female , larval stage | third instar , adult stage | female " ovary

" embryonic stage | 10 hr , embryonic stage , embryonic stage | early " " longitudinal connective

, epidermis

, embryonic/larval esophagus

, embryonic central nervous system

, ventral nerve cord commissure

" DRSC12623 IEK 3.122311164 -1.305856428 2.763135809 -2.032425659 2.139000413 0.819453992 FBgn0042105 CG18748 - http://flybase.org/reports/FBgn0042105 protein_coding_gene - - - "CG18748, CR18748" "IPR014756:Immunoglobulin E-set, IPR011022:Arrestin C-terminal-like domain, IPR011021:Arrestin-like, N-terminal" CG18748 11-Aug-17 DroID_v2017_08 "Drer\arrdc3a, Drer\LOC799768, Drer\arrdc3b, Drer\txnipb, Drer\txnipa, Drer\zgc:110626, Drer\si:ch211-130m23.2, Drer\zgc:110353, Drer\arrdc2, Drer\arrdc1b, Drer\arrdc1a" "Scer\LDB19, Scer\ALY1, Scer\ALY2, Scer\ROD1, Scer\ECM21, Scer\ART5, Scer\CSR2, Scer\RIM8, Scer\ROG3" "Cele\arrd-5, Cele\rnh-1.2, Cele\arrd-9, Cele\arrd-3, Cele\arrd-8, Cele\arrd-14, Cele\arrd-22, Cele\arrd-12, Cele\arrd-7, Cele\arrd-27, Cele\arrd-23, Cele\arrd-11, Cele\arrd-4, Cele\arrd-13, Cele\arrd-24, Cele\arrd-25, Cele\arrd-2, Cele\arrd-18, Cele\arrd-17, Cele\arrd-19, Cele\arrd-1, Cele\arrd-15, Cele\arrd-6, Cele\arrd-16" "Xtro\arrdc4, Xtro\arrdc2, Xtro\txnip, Xtro\arrdc3" "Mmus\Txnip, Mmus\Arrdc5, Mmus\Arrdc4, Mmus\Arrdc1, Mmus\Arrdc3, Mmus\Arrdc2" "Hsap\ARRDC1, Hsap\ARRDC5, Hsap\ARRDC4, Hsap\ARRDC2, Hsap\TXNIP, Hsap\ARRDC3" viable FBgn0032522 CG16848 - http://flybase.org/reports/FBgn0032522 protein_coding_gene FMN adenylyltransferase activity ; GO:0003919 | inferred from biological aspect of ancestor with PANTHER:PTN000591373 oxidation-reduction process ; GO:0055114 | inferred from biological aspect of ancestor with PANTHER:PTN000591370 FAD biosynthetic process ; GO:0006747 | inferred from biological aspect of ancestor with PANTHER:PTN000591373 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000591370 "FBgn0032522, CG16848" "IPR002500:Phosphoadenosine phosphosulphate reductase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG16848 11-Aug-17 DroID_v2017_08 Drer\flad1 "Scer\YMR178W, Scer\MET16, Scer\FAD1" Cele\flad-1 - Mmus\Flad1 Hsap\FLAD1 viable FBgn0013497 l(1)14Ag lethal (1) 14Ag http://flybase.org/reports/FBgn0013497 - gene - - - "II, l(1)II, l(1)13Fj, l(1)14Ag" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001571 l(1)52 lethal (1) 52 http://flybase.org/reports/FBgn0001571 - gene - - - l(1)52 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" "nervous system,testis,imaginal disc,embryonic/larval salivary gland" FBgn0070007 BG01485 BG01485 http://flybase.org/reports/FBgn0070007 gene - - - BG01485 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0052982 CG32982 - http://flybase.org/reports/FBgn0052982 protein_coding_gene - - - "CG9585, CG18566, CG9584, CG32982, p78" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG32982 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038122 CG8138 - http://flybase.org/reports/FBgn0038122 protein_coding_gene - - - CG8138 IPR027887:Protein of unknown function DUF4464 CG8138 11-Aug-17 DroID_v2017_08 Drer\si:ch211-57h10.1 - - - Mmus\1700007G11Rik Hsap\C4orf22 "viable,fertile" FBgn0053783 CG33783 - http://flybase.org/reports/FBgn0053783 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33783 IPR010512:Protein of unknown function DUF1091 CG33783 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026399 Or85e Odorant receptor 85e http://flybase.org/reports/FBgn0026399 - protein_coding_gene "odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 olfactory receptor activity ; GO:0004984 | inferred by curator from GO:0004888,GO:0007608" detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from expression pattern detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from sequence model dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "CG9700, 85e, DOR85e, DOR104, 85B.1, Dor104, dor104, Or104, CR9700, Or85e, OR85e, OR55" "IPR004117:Olfactory receptor, insect" CG9700 11-Aug-17 DroID_v2017_08 - - - - - - adult stage sensory neuron &&of maxillary palp sense organ

FBgn0085456 CG34427 - http://flybase.org/reports/FBgn0085456 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG34427, CG13307" IPR002557:Chitin binding domain CG34427 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013616 l(3)L2290 lethal (3) L2290 http://flybase.org/reports/FBgn0013616 - gene - - - l(3)L2290 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267142 CR45582 - http://flybase.org/reports/FBgn0267142 non_protein_coding_gene - - - CR45582 - CR45582 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036763 TrpRS-m "Tryptophanyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0036763 protein_coding_gene "tryptophan-tRNA ligase activity ; GO:0004830 | inferred from electronic annotation with InterPro:IPR002306, InterPro:IPR024109 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002305, InterPro:IPR002306 tryptophan-tRNA ligase activity ; GO:0004830 | traceable author statement" tryptophanyl-tRNA aminoacylation ; GO:0006436 | inferred from electronic annotation with InterPro:IPR002306 tryptophanyl-tRNA aminoacylation ; GO:0006436 | traceable author statement cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002306 mitochondrion ; GO:0005739 | traceable author statement "BEST:CK01295, GH31, CG7441, TrpRS-m" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002305:Aminoacyl-tRNA synthetase, class Ic, IPR002306:Tryptophan-tRNA ligase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR024109:Tryptophan-tRNA ligase, bacterial-type" CG7441 11-Aug-17 DroID_v2017_08 Drer\wars2 Scer\MSW1 Cele\prx-10 Xtro\wars2 Mmus\Wars2 Hsap\WARS2 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0002680 mat(2)syn-H maternal effect syncytial blastoderm arrest H http://flybase.org/reports/FBgn0002680 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)synRE48, mat(2)syn-H" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0069316 X-187-38 X-187-38 http://flybase.org/reports/FBgn0069316 gene - - - X-187-38 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267628 CR45966 - http://flybase.org/reports/FBgn0267628 non_protein_coding_gene - - - CR45966 - CR45966 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014054 Su(tor)2-341 Su(tor)2-341 http://flybase.org/reports/FBgn0014054 - gene - - - Su(tor)2-341 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0050296 RIC-3 RIC3 acetylcholine receptor chaperone http://flybase.org/reports/FBgn0050296 protein_coding_gene acetylcholine receptor binding ; GO:0033130 | inferred from biological aspect of ancestor with PANTHER:PTN000496889 unfolded protein binding ; GO:0051082 | inferred by curator from GO:0061077 "protein maturation by protein folding ; GO:0022417 | inferred from direct assay protein localization to cell surface ; GO:0034394 | inferred from biological aspect of ancestor with PANTHER:PTN000496889 synaptic transmission, cholinergic ; GO:0007271 | inferred from biological aspect of ancestor with PANTHER:PTN000496889 chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay" neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000496889 neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN000496889 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000496889 integral component of membrane ; GO:0016021 | inferred from sequence model "CG9349, CG15652, RIC-3, DmRIC-3, CG30296" "IPR032763:Resistance to inhibitors of cholinesterase protein 3, N-terminal, IPR026160:Resistance to inhibitors of cholinesterase protein 3" CG30296 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-278m9.1, Drer\ric3a, Drer\LOC101882410, Drer\ric3b" - Cele\ric-3 - Mmus\Ric3 Hsap\RIC3 DRSC04543 IK -0.674210135 -1.551179843 0.724130224 -0.002200115 -1.630441604 -1.132259193 FBgn0015579 2.1 2.1 http://flybase.org/reports/FBgn0015579 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available - 2.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002726 Mfcp Myofibrillar contractile protein http://flybase.org/reports/FBgn0002726 - gene - - - Mfcp - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043005 prt portabella http://flybase.org/reports/FBgn0043005 protein_coding_gene serotonin transmembrane transporter activity ; GO:0015222 | inferred from biological aspect of ancestor with PANTHER:PTN000607052 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 male mating behavior ; GO:0060179 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype aminergic neurotransmitter loading into synaptic vesicle ; GO:0015842 | inferred from biological aspect of ancestor with PANTHER:PTN000607052 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001519445 synaptic vesicle ; GO:0008021 | inferred from direct assay "CG10251, prt" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG10251 11-Aug-17 DroID_v2017_08 "Drer\slc18a2, Drer\slc18a3a, Drer\slc18a1" - "Cele\cat-1, Cele\F27D9.2" Xtro\slc18a1 "Mmus\Slc18a1, Mmus\Slc18a2" "Hsap\SLC18A3, Hsap\SLC18A2, Hsap\SLC18A1" "viable,fertile,learning defective,courtship behavior defective,male,mating defective" sex comb tooth FBgn0039965 CG13865 - http://flybase.org/reports/FBgn0039965 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG40301, CG13865, FBgn0039965" IPR006597:Sel1-like repeat CG13865 11-Aug-17 DroID_v2017_08 "Drer\coa7, Drer\mtap" Scer\SKT5 Cele\ZK20.4 "Xtro\mtap, Xtro\coa7" "Mmus\Coa7, Mmus\Mtap" Hsap\COA7 viable DRSC20967 EK 1.153889953 -0.211714862 1.99433468 0.495399308 1.585950296 1.893799129 FBgn0039908 Asator Asator http://flybase.org/reports/FBgn0039908 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966" regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 spindle ; GO:0005819 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 "CG11533, CK I, CKI-like, Asator" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG11533 11-Aug-17 DroID_v2017_08 "Drer\vrk2, Drer\csnk1db, Drer\csnk1da, Drer\ttbk1a, Drer\ttbk1b, Drer\vrk1, Drer\ttbk2b, Drer\ttbk2a, Drer\csnk1a1, Drer\csnk1e, Drer\vrk3" Scer\HRR25 "Cele\C05C12.1, Cele\ZC581.2, Cele\W03G9.5, Cele\T05C12.1, Cele\R90.1, Cele\F35C11.3, Cele\C49C8.1, Cele\C08F8.6, Cele\F56H11.6, Cele\M04F3.3, Cele\Y71F9AL.2, Cele\M7.7, Cele\T19D12.5, Cele\D2045.5, Cele\B0207.7, Cele\Y47G6A.13, Cele\ZK666.8, Cele\W01B6.2, Cele\F26A1.4, Cele\ZK596.2, Cele\C45G9.1, Cele\T11F8.4, Cele\ttbk-2, Cele\C04G2.2, Cele\F41G3.5, Cele\C39H7.1, Cele\F32B6.10, Cele\D2024.1, Cele\W09C3.1, Cele\Y38H8A.3, Cele\F54H5.2, Cele\B0218.5, Cele\tag-191, Cele\R10D12.10, Cele\ZK354.6, Cele\C03C10.2, Cele\K06H7.8, Cele\C25H3.1, Cele\W06F12.3, Cele\C56C10.6, Cele\C14A4.13" "Xtro\csnk1d, Xtro\ttbk2, Xtro\csnk1e, Xtro\vrk1, Xtro\csnk1a1, Xtro\vrk2, Xtro\vrk3" "Mmus\Csnk1e, Mmus\Vrk2, Mmus\Vrk1, Mmus\Ttbk2, Mmus\Vrk3, Mmus\Csnk1a1, Mmus\Csnk1d, Mmus\Ttbk1" "Hsap\CSNK1D, Hsap\VRK2, Hsap\TTBK1, Hsap\VRK1, Hsap\TTBK2, Hsap\CSNK1A1, Hsap\CSNK1A1L, Hsap\VRK3, Hsap\CSNK1E" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable" FBgn0032147 IP3K1 "Inositol 1,4,5-triphosphate kinase 1" http://flybase.org/reports/FBgn0032147 protein_coding_gene "inositol-1,4,5-trisphosphate 3-kinase activity ; GO:0008440 | inferred from electronic annotation with InterPro:IPR005522 calmodulin binding ; GO:0005516 | NOT inferred from direct assay" response to oxidative stress ; GO:0006979 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "dmIP3Kalpha, CG4026, D-IP3K1, UY530, anon-WO0118547.189, IP3K1, dmIP[[3]]Kalpha, IP3KI, IP[[3]]K-1" "IPR005522:Inositol polyphosphate kinase, IPR015943:WD40/YVTN repeat-like-containing domain" CG4026 11-Aug-17 DroID_v2017_08 "Drer\itpka, Drer\itpkca, Drer\si:ch73-22a13.3, Drer\itpkb, Drer\itpkcb" - Cele\lfe-2 "Xtro\itpkb, Xtro\itpka, Xtro\itpkc" "Mmus\Itpkb, Mmus\Itpka, Mmus\Itpkc" "Hsap\ITPKA, Hsap\ITPKB, Hsap\ITPKC" "viable,fertile,oxidative stress response defective,chemical sensitive,chemical resistant" Malpighian tubule FBgn0041744 l(1)em5 lethal (1) em5 http://flybase.org/reports/FBgn0041744 gene - - - l(1)em5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052082 IRSp53 - http://flybase.org/reports/FBgn0052082 protein_coding_gene phospholipid binding ; GO:0005543 | inferred from sequence or structural similarity with MGI:MGI:2652819 plasma membrane organization ; GO:0007009 | inferred from electronic annotation with InterPro:IPR013606 positive regulation of actin filament polymerization ; GO:0030838 | inferred from biological aspect of ancestor with PANTHER:PTN001022094 filopodium assembly ; GO:0046847 | inferred from mutant phenotype membrane organization ; GO:0061024 | inferred from sequence or structural similarity with MGI:MGI:2652819 positive regulation of actin cytoskeleton reorganization ; GO:2000251 | inferred from biological aspect of ancestor with PANTHER:PTN001022094 insulin receptor signaling pathway ; GO:0008286 | inferred from biological aspect of ancestor with PANTHER:PTN001022094 actin crosslink formation ; GO:0051764 | inferred from biological aspect of ancestor with PANTHER:PTN001022094 actin filament bundle assembly ; GO:0051017 | inferred from biological aspect of ancestor with PANTHER:PTN001022094 actin cytoskeleton ; GO:0015629 | inferred from biological aspect of ancestor with PANTHER:PTN001022094 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001022094 "CG7624, anon-WO0118547.199, CG32082, IRSp53" "IPR001452:SH3 domain, IPR013606:IMD/I-BAR domain, IPR027681:I-BAR domain containing protein IRSp53/IRTKS/Pinkbar, IPR027267:Arfaptin homology (AH) domain/BAR domain" CG32082 11-Aug-17 DroID_v2017_08 "Drer\baiap2a, Drer\alg10, Drer\baiap2l2b, Drer\baiap2l2a, Drer\baiap2l1a, Drer\zgc:158689, Drer\baiap2b, Drer\mtss1, Drer\baiap2l1b" Scer\DIE2 Cele\Y45F3A.1 "Xtro\baiap2l1, Xtro\pacsin3, Xtro\alg10, Xtro\baiap2, Xtro\baiap2l2, Xtro\mtss1.1, Xtro\LOC100485322" "Mmus\Pacsin3, Mmus\Alg10b, Mmus\Mtss1l, Mmus\Baiap2l2, Mmus\Baiap2l1, Mmus\Baiap2" "Hsap\ALG10, Hsap\PACSIN3, Hsap\ALG10B, Hsap\BAIAP2L2, Hsap\BAIAP2, Hsap\BAIAP2L1" FBgn0033166 Eaf ELL-associated factor http://flybase.org/reports/FBgn0033166 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VW51 "wound healing ; GO:0042060 | inferred from mutant phenotype regulation of DNA-templated transcription in response to stress ; GO:0043620 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with UniProtKB:Q91ZD6 transcription elongation factor complex ; GO:0008023 | inferred from direct assay ELL-EAF complex ; GO:0032783 | inferred from physical interaction with Su(Tpl) nucleoplasm ; GO:0005654 | inferred from direct assay "LD35207, EP(2)2475, CG1706, Eaf, CG11166, dEaf" "IPR027093:EAF family, IPR019194:Transcription elognation factor Eaf, N-terminal" CG11166 11-Aug-17 DroID_v2017_08 "Drer\eaf1, Drer\eaf2" - Cele\eaf-1 "Xtro\eaf2, Xtro\eaf1" "Mmus\Eaf1, Mmus\Eaf2" "Hsap\EAF1, Hsap\EAF2" "lethal,viable,visible" trichogen cell FBgn0001662 l(1)E25 lethal (1) E25 http://flybase.org/reports/FBgn0001662 - gene - - - "l(1)E25[ts], l(1)E25" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,maternal effect" FBgn0052677 X11Lbeta X11Lbeta http://flybase.org/reports/FBgn0052677 protein_coding_gene - protein localization to membrane ; GO:0072657 | inferred from mutant phenotype - "CG1861, CG1852, X11B, X11Lbeta, CG32677, x11Lbeta, Dmint2, X11lbeta, X11LB" "IPR001478:PDZ domain, IPR006020:PTB/PI domain, IPR011993:PH domain-like, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain" CG32677 11-Aug-17 DroID_v2017_08 "Drer\apba1a, Drer\apba2a, Drer\apba2b, Drer\si:ch73-40i7.5, Drer\apba1b" - Cele\lin-10 Xtro\apba2 "Mmus\Apba3, Mmus\Apba2, Mmus\Apba1" "Hsap\APBA3, Hsap\APBA2, Hsap\APBA1" "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell FBgn0052040 CG32040 - http://flybase.org/reports/FBgn0052040 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32040 - CG32040 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043896 im(1)179 im(1)179 http://flybase.org/reports/FBgn0043896 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "FB179, im(1)179" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064190 beb bebra http://flybase.org/reports/FBgn0064190 gene molecular_function ; GO:0003674 | no biological data available pole plasm assembly ; GO:0007315 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available beb - - 11-Aug-17 DroID_v2017_08 - - - - - - "pole cell,germline clone,maternal effect" FBgn0028343 Ankle2 Ankyrin repeat and LEM domain containing 2 http://flybase.org/reports/FBgn0028343 protein_coding_gene protein phosphatase 2A binding ; GO:0051721 | inferred from biological aspect of ancestor with PANTHER:PTN000469495 negative regulation of phosphorylation ; GO:0042326 | inferred from biological aspect of ancestor with PANTHER:PTN000469495 mitotic nuclear envelope reassembly ; GO:0007084 | inferred from biological aspect of ancestor with PANTHER:PTN000469495 positive regulation of protein dephosphorylation ; GO:0035307 | inferred from biological aspect of ancestor with PANTHER:PTN000469495 cell morphogenesis ; GO:0000902 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG8465, l(1)G0316, anon-WO03040301.179, anon-WO03040301.177, anon-WO03040301.175, l(1)G0222, Ankle2, dAnkle2" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG8465 11-Aug-17 DroID_v2017_08 "Drer\LOC569920, Drer\ankle2, Drer\zdhhc8a" - Cele\lem-4 Xtro\ankle2 Mmus\Ankle2 Hsap\ANKLE2 "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0035486 Gr64d Gustatory receptor 64d http://flybase.org/reports/FBgn0035486 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype taste receptor activity ; GO:0008527 | non-traceable author statement "detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from electronic annotation with InterPro:IPR009318 sensory perception of sweet taste ; GO:0050916 | inferred from genetic interaction with Gr64e, Gr64c, Gr64b, Gr64a, Gr64f detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009318 integral component of membrane ; GO:0016021 | non-traceable author statement "CG14987, CG33157, Gr64d, Dmel64d, Gr64, GR64d" IPR009318:Gustatory receptor CG14987 11-Aug-17 DroID_v2017_08 - - - - - - taste perception defective FBgn0027200 l(1)H21 lethal (1) H21 http://flybase.org/reports/FBgn0027200 - gene - - - l(1)H21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267991 CR46258 - http://flybase.org/reports/FBgn0267991 non_protein_coding_gene - - - CR46258 - CR46258 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029706 CG3626 - http://flybase.org/reports/FBgn0029706 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000354057 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR023753" mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN002302636 CG3626 "IPR006076:FAD dependent oxidoreductase, IPR006222:Glycine cleavage T-protein-like, N-terminal, IPR013977:Glycine cleavage T-protein, C-terminal barrel domain, IPR029043:Glycine cleavage T-protein/YgfZ, C-terminal domain, IPR032503:FAD dependent oxidoreductase, central domain, IPR023753:FAD/NAD(P)-binding domain" CG3626 11-Aug-17 DroID_v2017_08 "Drer\dmgdh, Drer\pdpr, Drer\sardh" Scer\GCV1 Cele\Y106G6H.5 "Xtro\dmgdh, Xtro\pdpr, Xtro\sardh" "Mmus\Pdpr, Mmus\Dmgdh, Mmus\Sardh" "Hsap\SARDH, Hsap\PDPR, Hsap\DMGDH" "viable,fertile" FBgn0261112 APP-BP1 beta-Amyloid precursor protein binding protein 1 http://flybase.org/reports/FBgn0261112 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with UniProtKB:Q13564 protein binding ; GO:0005515 | inferred from physical interaction with Appl NEDD8 activating enzyme activity ; GO:0019781 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q13564 NEDD8 activating enzyme activity ; GO:0019781 | contributes_to inferred from direct assay NEDD8 activating enzyme activity ; GO:0019781 | contributes_to inferred from sequence or structural similarity with HGNC:621 beta-amyloid binding ; GO:0001540 | inferred from physical interaction with UniProtKB:P14599 protein neddylation ; GO:0045116 | inferred from sequence or structural similarity with HGNC:621 inferred from mutant phenotype protein neddylation ; GO:0045116 | inferred from sequence or structural similarity with UniProtKB:Q13564 protein neddylation ; GO:0045116 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Uba3 "dAPPBP1, APP-BP1, dAPP-BP1, APPBP1, anon-WO0140519.225, CG7828" "IPR030667:NEDD8-activating enzyme E1 regulatory subunit APP-BP1, IPR000594:THIF-type NAD/FAD binding fold" CG7828 11-Aug-17 DroID_v2017_08 "Drer\nae1, Drer\sae1" "Scer\ULA1, Scer\AOS1" "Cele\uba-1, Cele\aos-1, Cele\ula-1" "Xtro\nae1, Xtro\sae1" "Mmus\Sae1, Mmus\Nae1" "Hsap\SAE1, Hsap\NAE1" FBgn0025564 anon-23Cb anon-23Cb http://flybase.org/reports/FBgn0025564 - gene - - - "c1.5, anon-23Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051800 CG31800 - http://flybase.org/reports/FBgn0051800 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31800 IPR019534:Protein of unknown function DUF2452 CG31800 11-Aug-17 DroID_v2017_08 Drer\zgc:112255 - Cele\C08B11.9 Xtro\c1orf50 Mmus\AU022252 "Hsap\LOC100129924, Hsap\C1orf50" viable FBgn0065192 l(2)SH2328 lethal (2) SH2328 http://flybase.org/reports/FBgn0065192 gene - - - "l(2)SH2328, l(2)SH2 2328" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0042086 Tsp42Eb Tetraspanin 42Eb http://flybase.org/reports/FBgn0042086 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000301, InterPro:IPR008952, InterPro:IPR018499" "CG18816, Dm.Tsp42Eb, LP06288, BEST:LP06288, Tsp42Eb, Tetrasp42Eb" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG18816 11-Aug-17 DroID_v2017_08 Drer\cd63 - "Cele\tsp-2, Cele\tsp-7, Cele\tsp-14, Cele\tsp-3, Cele\tsp-1" - Mmus\Cd63 Hsap\CD63 FBgn0026761 Trap1 Trap1 http://flybase.org/reports/FBgn0026761 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001404 unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001404 protein kinase binding ; GO:0019901 | inferred from sequence or structural similarity with UniProtKB:Q12931 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:Q12931 ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with HGNC:16264 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001404 mitochondrial unfolded protein response ; GO:0034514 | inferred from mutant phenotype inferred from genetic interaction with dve inferred from genetic interaction with CG5045 response to heat ; GO:0009408 | inferred from mutant phenotype positive regulation of response to oxidative stress ; GO:1902884 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:16264 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q12931 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with UniProtKB:Q12931 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q12931 lipid particle ; GO:0005811 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q12931 "TRAP1, Trap1, dtrap-1, TRAP1dr, CG3152, trap1, AAN71071" "IPR001404:Heat shock protein Hsp90 family, IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR020575:Heat shock protein Hsp90, N-terminal" CG3152 11-Aug-17 DroID_v2017_08 "Drer\trap1, Drer\hsp90aa1.2, Drer\hsp90ab1" "Scer\HSC82, Scer\HSP82" Cele\hsp-75 "Xtro\hsp90aa1.1, Xtro\hsp90ab1, Xtro\trap1" "Mmus\Hsp90aa1, Mmus\Hsp90ab1, Mmus\Trap1" "Hsap\TRAP1, Hsap\HSP90AB1, Hsap\HSP90AA1" "viable,short lived,heat stress response defective,oxidative stress response defective,chemical sensitive,locomotor behavior defective,progressive,chemical resistant,fertile" FBgn0083248 EB2 EB2 http://flybase.org/reports/FBgn0083248 gene - - - EB2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000737 fs(1)A97 female sterile (1) A97 http://flybase.org/reports/FBgn0000737 - gene - - - "fs(1)97, fs(1)A97" - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0261599 RpS29 Ribosomal protein S29 http://flybase.org/reports/FBgn0261599 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001209, InterPro:IPR018271 structural constituent of ribosome ; GO:0003735 | traceable author statement zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000244187" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001209, InterPro:IPR018271 neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement neuron development ; GO:0048666 | inferred from mutant phenotype" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001209, InterPro:IPR018271 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement" "RpS29, CG8495, M(3)85E, anon-EST:fe3B4, BcDNA:RH06643, BcDNA:AT13329, BcDNA:AT28563, anon-WO0118547.360, M(3)LS5, chr3R:5604479..5604622" "IPR018271:Ribosomal protein S14, conserved site, IPR001209:Ribosomal protein S14" CG8495 11-Aug-17 DroID_v2017_08 "Drer\tmem256, Drer\rps29" "Scer\RPS29A, Scer\RPS29B" "Cele\Y106G6H.8, Cele\rps-29" "Xtro\tmem256, Xtro\rps29" "Mmus\Rps29, Mmus\Tmem256" "Hsap\TMEM256, Hsap\RPS29" DRSC16433 IEK -1.90097173 -0.687411618 -1.003828682 -3.844410139 0.307976209 2.328242392 FBgn0050015 CG30015 - http://flybase.org/reports/FBgn0050015 protein_coding_gene - - - "CG30015, anon-EST:Posey2, CG7701, CG7699" IPR031764:Domain of unknown function DUF4739 CG30015 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC07027 K 0.474843328 0.367340697 0.465262046 0.429242465 0.48105363 1.829455721 FBgn0040153 l(1)G0469 lethal (1) G0469 http://flybase.org/reports/FBgn0040153 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG11595, CG12482, CG32597, anon-WO03040301.232, l(1)G0469" - CG32597 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage,viable" DRSC19412 E 0.42937985 0.579799864 1.902219807 0.390430675 -0.383355396 -0.39756549 FBgn0262821 CG43192 - http://flybase.org/reports/FBgn0262821 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43192, noncoding_6907, noncoding_6564" - CG43192 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029737 CG6903 - http://flybase.org/reports/FBgn0029737 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from biological aspect of ancestor with PANTHER:PTN001257525 transferase activity, transferring acyl groups ; GO:0016746 | inferred from sequence or structural similarity with HGNC:26527" lysosomal transport ; GO:0007041 | inferred from sequence or structural similarity with HGNC:26527 lysosomal membrane ; GO:0005765 | inferred from sequence or structural similarity with HGNC:26527 CG6903 IPR032176:Domain of unknown function DUF5009 CG6903 11-Aug-17 DroID_v2017_08 "Drer\hgsnat, Drer\si:dkey-192p21.6" - Cele\fbxa-112 Xtro\hgsnat Mmus\Hgsnat Hsap\HGSNAT "viable,fertile" FBgn0020861 corallium corallium http://flybase.org/reports/FBgn0020861 - gene - - - "corallium, cor" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0027600 obst-B obstructor-B http://flybase.org/reports/FBgn0027600 FBgn0028958 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CK00178, BcDNA:GH02976, BEST:CK00178, obst-B, CG4778" IPR002557:Chitin binding domain CG4778 11-Aug-17 DroID_v2017_08 - - "Cele\cbd-1, Cele\dct-9, Cele\R02F2.4, Cele\cpg-2" - - - viable FBgn0028181 l(3)S024506 lethal (3) S024506 http://flybase.org/reports/FBgn0028181 gene - - - "0245/06, l(3)S024506" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0260000 CG17570 - http://flybase.org/reports/FBgn0260000 protein_coding_gene - - - "anon-38C.24, CG17570, 38C.24" - CG17570 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035693 CG8219 - http://flybase.org/reports/FBgn0035693 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "protein import into nucleus, translocation ; GO:0000060 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 ribosomal protein import into nucleus ; GO:0006610 | inferred from biological aspect of ancestor with PANTHER:PTN000055427" nuclear periphery ; GO:0034399 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "148274_at, EP(3)3072, CG8219" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG8219 11-Aug-17 DroID_v2017_08 "Drer\tnpo2, Drer\LOC100005536, Drer\tnpo1" Scer\KAP104 Cele\imb-2 "Xtro\tnpo2, Xtro\tnpo1" "Mmus\Tnpo1, Mmus\Tnpo2" "Hsap\TNPO1, Hsap\TNPO2" "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030554 CG1434 - http://flybase.org/reports/FBgn0030554 protein_coding_gene "tRNA dihydrouridine synthase activity ; GO:0017150 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517" - CG1434 "IPR001269:tRNA-dihydrouridine synthase, IPR018517:tRNA-dihydrouridine synthase, conserved site, IPR013785:Aldolase-type TIM barrel, IPR014720:Double-stranded RNA-binding domain" CG1434 11-Aug-17 DroID_v2017_08 Drer\dus2 Scer\SMM1 Cele\Y54E5A.6 Xtro\dus2 Mmus\Dus2 Hsap\DUS2 viable FBgn0060533 l(3)S100806 lethal (3) S100806 http://flybase.org/reports/FBgn0060533 gene - - - "1008/06, l(3)S100806" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0037794 CG6254 - http://flybase.org/reports/FBgn0037794 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG6254 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG6254 11-Aug-17 DroID_v2017_08 "Drer\prdm10, Drer\zgc:113096, Drer\zbtb33" - "Cele\tra-4, Cele\M03D4.4, Cele\F58G1.2, Cele\sdz-12, Cele\pag-3, Cele\Y55F3AM.14, Cele\fezf-1" - "Mmus\Prdm10, Mmus\Zfp324, Mmus\Zfp128" "Hsap\ZNF133, Hsap\ZNF222, Hsap\ZNF232, Hsap\ZNF124, Hsap\PRDM10" viable FBgn0043530 Obp51a Odorant-binding protein 51a http://flybase.org/reports/FBgn0043530 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "51a, Obp-c, anon-AE003812.1, CG30473, Obp51a, DmelObp51a" IPR006170:Pheromone/general odorant binding protein CG30473 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010244 Mst77F-PsiY2 Mst77F pseudogene on Y 2 http://flybase.org/reports/FBgn0010244 - pseudogene_attribute - - - "18c, Mst77F-PsiY2, Mst77-Psi2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261383 IntS6 Integrator 6 http://flybase.org/reports/FBgn0261383 protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA 3'-end processing ; GO:0034472 | inferred from direct assay snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:14879 integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:14879 "CG3125, IntS6, Int6, l(1)G0060" "IPR002035:von Willebrand factor, type A, IPR029307:INTS6/SAGE1/DDX26B/CT45, C-terminal" CG3125 11-Aug-17 DroID_v2017_08 "Drer\ddx26b, Drer\ints6" - Cele\dic-1 "Xtro\ints6l, Xtro\ints6" "Mmus\Ints6, Mmus\Ints6l, Mmus\Gm648" "Hsap\CT45A2, Hsap\CT45A6, Hsap\INTS6, Hsap\CT45A3, Hsap\CT45A9, Hsap\CT45A7, Hsap\INTS6L, Hsap\SAGE1, Hsap\CT45A8, Hsap\CT45A10, Hsap\CT45A1, Hsap\CT45A5" "lethal,recessive,viable,fertile" DRSC18281 I 0.637531439 -2.118115405 1.285873248 -1.289482666 0.465003313 0.336119248 FBgn0004137 l(2)43Ef lethal (2) 43Ef http://flybase.org/reports/FBgn0004137 - gene - - - l(2)43Ef - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003218 rdgB retinal degeneration B http://flybase.org/reports/FBgn0003218 - protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR004177 phosphatidylinositol transporter activity ; GO:0008526 | inferred from direct assay phosphatidylinositol binding ; GO:0035091 | inferred from direct assay phosphatidylinositol transporter activity ; GO:0008526 | non-traceable author statement phosphatidylcholine transporter activity ; GO:0008525 | inferred from direct assay phosphatidic acid transporter activity ; GO:1990050 | inferred from direct assay phosphatidic acid binding ; GO:0070300 | inferred from direct assay calcium-transporting ATPase activity ; GO:0005388 | inferred from sequence or structural similarity "sensory perception of smell ; GO:0007608 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | traceable author statement deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype phototransduction ; GO:0007602 | traceable author statement cellular response to light stimulus ; GO:0071482 | inferred from mutant phenotype phosphatidylinositol metabolic process ; GO:0046488 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype phospholipid transport ; GO:0015914 | inferred from direct assay rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype" intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001666 subrhabdomeral cisterna ; GO:0016029 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | traceable author statement subrhabdomeral cisterna ; GO:0016029 | traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "RdgBalpha, DrdgBalpha, DrdgB, ota1, x36, hypoF, CG11111, rdgB, RdgB, rdbB(ota1)" "IPR001666:Phosphatidylinositol transfer protein, IPR004177:DDHD domain, IPR023393:START-like domain, IPR023214:HAD-like domain, IPR031315:LNS2/PITP" CG11111 11-Aug-17 DroID_v2017_08 "Drer\zgc:101640, Drer\pitpnbl, Drer\pitpnc1, Drer\pitpnab, Drer\pitpnaa, Drer\plrdgb, Drer\pitpnm3, Drer\pitpnm2, Drer\LOC101882041" Scer\YOR022C Cele\pitp-1 "Xtro\pitpnm3, Xtro\pitpnb.2, Xtro\pitpnc1, Xtro\pitpnm2, Xtro\pitpnb" "Mmus\Pitpnm2, Mmus\Pitpnm1, Mmus\Pitpnb, Mmus\Pitpnc1, Mmus\Pitpnm3, Mmus\Pitpna" "Hsap\PITPNM2, Hsap\PITPNM1, Hsap\PITPNM3, Hsap\PITPNB, Hsap\PITPNC1, Hsap\PITPNA" adult stage adult head

"smell perception defective,recessive,behavior defective,neuroanatomy defective,visual behavior defective,neurophysiology defective,viable,dominant" "eye photoreceptor cell,ommatidium,retina,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,glial cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell,rhabdomere,cell autonomous,somatic clone,lamina,maxillary palpus,photoreceptor cell R7,photoreceptor cell R8,ocellus rhabdomere,ocellus retinula cell,rhabdomere R7" FBgn0040892 CG14634 - http://flybase.org/reports/FBgn0040892 protein_coding_gene - - - CG14634 - CG14634 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0267096 CR45536 - http://flybase.org/reports/FBgn0267096 non_protein_coding_gene - - - CR45536 - CR45536 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053914 CG33914 - http://flybase.org/reports/FBgn0053914 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33914 IPR010512:Protein of unknown function DUF1091 CG33914 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024274 Vitamin-D-hydroxylase Vitamin D hydroxylase http://flybase.org/reports/FBgn0024274 - gene - - - Vitamin-D-hydroxylase - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052645 CG32645 - http://flybase.org/reports/FBgn0052645 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - "CG4331, CG15716, CG32645" "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG32645 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-54, Cele\oac-20, Cele\oac-31, Cele\oac-53, Cele\oac-50, Cele\oac-3, Cele\oac-46, Cele\oac-9, Cele\oac-14, Cele\oac-5, Cele\oac-6, Cele\ndg-4, Cele\oac-7, Cele\oac-32, Cele\oac-55, Cele\oac-39, Cele\nrf-6, Cele\rhy-1" - Mmus\Oacyl - "viable,fertile,lethal,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267996 CR46263 - http://flybase.org/reports/FBgn0267996 non_protein_coding_gene - - - CR46263 - CR46263 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037217 CG14636 - http://flybase.org/reports/FBgn0037217 protein_coding_gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - CG14636 - CG14636 11-Aug-17 DroID_v2017_08 - - - - - - "auditory perception defective,viable,fertile" FBgn0029552 CG14631 - http://flybase.org/reports/FBgn0029552 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14631 - CG14631 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011088 l(1)Q48 lethal (1) Q48 http://flybase.org/reports/FBgn0011088 FBgn0010210 gene - - - l(1)Q48 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035982 CG4461 - http://flybase.org/reports/FBgn0035982 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model response to heat ; GO:0009408 | inferred from direct assay chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model cellular_component ; GO:0005575 | no biological data available "Dmel23.8, Hsp20, 148460_at, gh12586, BEST:GH12586, CG4461, 4461, DmCG4461" "IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4461 11-Aug-17 DroID_v2017_08 "Drer\cryaa, Drer\hspb2, Drer\hspb12, Drer\cryaba, Drer\hspb6, Drer\hspb11, Drer\hspb3, Drer\hspb8, Drer\hspb7, Drer\hspb9, Drer\hspb15, Drer\si:dkey-1k23.3, Drer\hspb1" - "Cele\hsp-16.2, Cele\hsp-16.1, Cele\hsp-12.6, Cele\hsp-43, Cele\hsp-16.49, Cele\Y55F3BR.6, Cele\hsp-17, Cele\hsp-12.3, Cele\hsp-16.41, Cele\hsp-16.48, Cele\ZK1128.7, Cele\hsp-16.11, Cele\F08H9.3, Cele\sip-1, Cele\hsp-12.2, Cele\hsp-12.1, Cele\F08H9.4" "Xtro\hsp30d, Xtro\hspb1, Xtro\hspb2, Xtro\cryaa, Xtro\hspb8, Xtro\hspb6, Xtro\cryab, Xtro\uqcrh, Xtro\hspb3" "Mmus\Hspb1, Mmus\Hspb3, Mmus\Hspb7, Mmus\Hspb9, Mmus\Cryab, Mmus\Hspb8, Mmus\Cryaa, Mmus\Hspb6, Mmus\Hspb2" "Hsap\HSPB1, Hsap\LOC102724652, Hsap\CRYAA, Hsap\CRYAB, Hsap\HSPB2, Hsap\HSPB9, Hsap\HSPB7, Hsap\HSPB3, Hsap\HSPB6, Hsap\HSPB8" viable DRSC10423 K 0.694015053 0.382321768 0.284991205 0.242377893 -0.19085145 1.532109202 FBgn0259837 Su(Ste):CR42406 Su(Ste):CR42406 http://flybase.org/reports/FBgn0259837 non_protein_coding_gene - - - "Su(Ste):CR42406, RR42186, CR42406" - CR42406 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037730 CG9444 - http://flybase.org/reports/FBgn0037730 protein_coding_gene "transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR000109, InterPro:IPR018456" oligopeptide transport ; GO:0006857 | inferred from electronic annotation with InterPro:IPR018456 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000109, InterPro:IPR018456" CG9444 "IPR000109:Proton-dependent oligopeptide transporter family, IPR020846:Major facilitator superfamily domain, IPR018456:PTR2 family proton/oligopeptide symporter, conserved site" CG9444 11-Aug-17 DroID_v2017_08 "Drer\slc15a4, Drer\slc15a1b, Drer\slc15a1a, Drer\si:ch211-190o6.3, Drer\slc15a2" Scer\PTR2 "Cele\pept-2, Cele\pept-3, Cele\pept-1" "Xtro\slc15a4, Xtro\slc15a2" "Mmus\Slc15a3, Mmus\Slc15a2, Mmus\Slc15a4, Mmus\Slc15a1, Mmus\Slc15a5" "Hsap\SLC15A5, Hsap\SLC15A1, Hsap\SLC15A2, Hsap\SLC15A4, Hsap\SLC15A3" "viable,fertile" FBgn0023224 E(Egfr)B56 Enhancer of Egfr B56 http://flybase.org/reports/FBgn0023224 - gene - - - E(Egfr)B56 - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing vein L2,wing vein L4,wing vein L5" FBgn0020787 re-o red-orange http://flybase.org/reports/FBgn0020787 - gene - - - re-o - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0265942 CR44729 - http://flybase.org/reports/FBgn0265942 non_protein_coding_gene - - - CR44729 - CR44729 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030114 CG17754 - http://flybase.org/reports/FBgn0030114 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 phagocytosis ; GO:0006909 | inferred from mutant phenotype Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from biological aspect of ancestor with PANTHER:PTN001973695 "BcDNA:LP02641, CG17754" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR017096:BTB-kelch protein, IPR015915:Kelch-type beta propeller" CG17754 11-Aug-17 DroID_v2017_08 "Drer\kbtbd11, Drer\klhl3, Drer\klhl4, Drer\klhl30, Drer\si:dkey-260j18.2, Drer\klhl22, Drer\klhl18, Drer\klhl2, Drer\gan, Drer\klhl8, Drer\klhl5, Drer\klhl12, Drer\klhl17, Drer\klhl20, Drer\si:ch73-29c22.1" - "Cele\C53A5.9, Cele\R12E2.1, Cele\spe-26, Cele\C53A5.6, Cele\kel-1, Cele\kel-3, Cele\C53A5.11" "Xtro\klhl20, Xtro\klhl17, Xtro\klhl5, Xtro\klhl12, Xtro\klhl4" "Mmus\Klhl12, Mmus\Gan, Mmus\Klhl1, Mmus\Klhl18, Mmus\Klhl4, Mmus\Klhl8, Mmus\Klhl3, Mmus\Klhl22, Mmus\Klhl5, Mmus\Klhdc7b, Mmus\Klhl17, Mmus\Kbtbd11, Mmus\Klhdc7a, Mmus\Klhl30, Mmus\Klhl2, Mmus\Klhl20" "Hsap\KLHL3, Hsap\KLHL12, Hsap\KLHL4, Hsap\KBTBD11, Hsap\KLHDC7A, Hsap\KLHL18, Hsap\KLHL5, Hsap\KLHL2, Hsap\KLHL8, Hsap\KLHL20, Hsap\KLHL30, Hsap\KLHDC7B, Hsap\KLHL1, Hsap\GAN, Hsap\KLHL22, Hsap\KLHL17" "viable,fertile" FBgn0004692 Sgs9 Salivary gland secretion 9 http://flybase.org/reports/FBgn0004692 - gene structural molecule activity ; GO:0005198 | inferred from direct assay puparial adhesion ; GO:0007594 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay "Sgs, P5, GP5, Sgs9" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262566 CG43106 - http://flybase.org/reports/FBgn0262566 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43106 - CG43106 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000483 dotted dotted http://flybase.org/reports/FBgn0000483 - gene - - - "dotted, dot" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,maternal effect,recessive,some die during larval stage" FBgn0086778 nAChRalpha7 nicotinic Acetylcholine Receptor alpha7 http://flybase.org/reports/FBgn0086778 protein_coding_gene acetylcholine-gated cation channel activity ; GO:0022848 | inferred from direct assay acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity "chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype synaptic transmission, cholinergic ; GO:0007271 | inferred from expression pattern jump response ; GO:0007630 | inferred from mutant phenotype excitatory postsynaptic potential ; GO:0060079 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from direct assay visual behavior ; GO:0007632 | inferred from mutant phenotype" "postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity dendrite ; GO:0030425 | inferred from direct assay dendritic spine ; GO:0043197 | inferred from direct assay postsynaptic density ; GO:0014069 | inferred from direct assay acetylcholine-gated channel complex ; GO:0005892 | inferred from physical interaction with nAChRα5, nAChRα6" "Dalpha7, nAcRalpha-18C, nAChR, CT24218, CG8109, CG8082, CG32538, nj75, nj54, nj522, nj520, nj507, jpl, gfa, gfA, nAcRalpha-7, Da7, Dalpha7 nAChR, Dalpha7-nAChR, nAChRalpha7, nAChR-Dalpha7, nAcRalpha18C, nAChR-gfa, nAchRa7" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG32538 11-Aug-17 DroID_v2017_08 "Drer\chrna9, Drer\chrng, Drer\LOC101882451, Drer\chrnd, Drer\LOC798522, Drer\chrnb3a, Drer\si:ch73-380n15.2, Drer\chrnb4, Drer\chrnb1l, Drer\chrna2b, Drer\chrna7, Drer\chrna2a, Drer\chrne, Drer\chrnb1, Drer\chrnb3b, Drer\si:ch211-39a7.1, Drer\chrna10a, Drer\chrnb2b, Drer\chrna4b, Drer\chrna3, Drer\chrna1, Drer\chrna6, Drer\chrnb2l" - "Cele\acr-12, Cele\acr-16, Cele\acr-6, Cele\eat-2, Cele\acr-2, Cele\acr-9, Cele\acr-15, Cele\acr-8, Cele\acr-19, Cele\W10G11.17, Cele\lgc-4, Cele\acr-3, Cele\unc-38, Cele\acr-21, Cele\acr-7, Cele\acr-25, Cele\lev-1, Cele\unc-63, Cele\acr-10, Cele\acr-11, Cele\acr-14" "Xtro\chrna7, Xtro\chrna1.2, Xtro\chrna6, Xtro\chrng, Xtro\chrna2, Xtro\chrna5, Xtro\chrna9, Xtro\LOC100487782, Xtro\chrnb2, Xtro\chrne, Xtro\chrnb3, Xtro\chrna1, Xtro\chrnd" "Mmus\Chrna4, Mmus\Chrng, Mmus\Chrnb1, Mmus\Chrnb3, Mmus\Chrne, Mmus\Chrna2, Mmus\Chrnd, Mmus\Chrna10, Mmus\Chrna1, Mmus\Chrna5, Mmus\Chrna9, Mmus\Chrnb4, Mmus\Chrna6, Mmus\Chrna7, Mmus\Chrna3" "Hsap\CHRNB2, Hsap\CHRNA1, Hsap\CHRNA2, Hsap\CHRNG, Hsap\CHRNA6, Hsap\CHRNA7, Hsap\CHRNA10, Hsap\CHRNA4, Hsap\CHRNA5, Hsap\CHRNA9, Hsap\CHRNB1, Hsap\CHRNE, Hsap\CHRNA3, Hsap\CHRNB4, Hsap\CHRNB3, Hsap\CHRND, Hsap\CHRFAM7A" FBgn0069195 l(2)c00221 lethal (2) c00221 http://flybase.org/reports/FBgn0069195 gene - - - l(2)c00221 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033995 GPHR Golgi pH Regulator http://flybase.org/reports/FBgn0033995 protein_coding_gene voltage-gated anion channel activity ; GO:0008308 | inferred from genetic interaction with UniProtKB:B7ZAQ6 voltage-gated anion channel activity ; GO:0008308 | inferred from biological aspect of ancestor with PANTHER:PTN000409301 intracellular pH reduction ; GO:0051452 | inferred from genetic interaction with UniProtKB:B7ZAQ6 secretion by cell ; GO:0032940 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype intracellular pH reduction ; GO:0051452 | inferred from biological aspect of ancestor with PANTHER:PTN000409301 integral component of membrane ; GO:0016021 | inferred from sequence model Golgi cisterna membrane ; GO:0032580 | inferred from biological aspect of ancestor with PANTHER:PTN000409301 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG8090, GPHR, dGPHR" "IPR015672:The Golgi pH regulator/GPCR-type G protein, IPR022535:Golgi pH regulator, conserved domain, IPR025969:Abscisic acid G-protein coupled receptor-like domain" CG8090 11-Aug-17 DroID_v2017_08 Drer\si:ch73-390b10.2 Scer\YHR078W "Cele\Y75B8A.16, Cele\C11H1.2" Xtro\gpr89b Mmus\Gpr89 "Hsap\GPR89B, Hsap\GPR89A" "lethal - all die before end of larval stage,small body,decreased cell size,decreased cell number,viable" "wing blade,endoplasmic reticulum,cis-Golgi network" FBgn0037963 Cad87A Cadherin 87A http://flybase.org/reports/FBgn0037963 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR020894 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "DCad87A, CG6977, CT21611, Cad87A, Cad87" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site" CG6977 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-186j3.6, Drer\LOC101882199, Drer\si:dkey-22o22.2, Drer\cdh23, Drer\pcdh2g1" - "Cele\cdh-7, Cele\cdh-12, Cele\fmi-1, Cele\cdh-9" - "Mmus\Pcdhb17, Mmus\Pcdha11, Mmus\Cdh23, Mmus\Pcdhb1, Mmus\Cdhr3" "Hsap\CDH23, Hsap\PCDHB7, Hsap\PCDHB15, Hsap\PCDHB1, Hsap\PCDHA12, Hsap\CDHR3, Hsap\PCDHA6" "viable,fertile" FBgn0030788 Sap30 SIN3-associated polypeptide 30 http://flybase.org/reports/FBgn0030788 protein_coding_gene histone deacetylase activity ; GO:0004407 | inferred from biological aspect of ancestor with PANTHER:PTN000328752 transcription cofactor activity ; GO:0003712 | inferred from biological aspect of ancestor with PANTHER:PTN000328752 "regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000328752" histone deacetylase complex ; GO:0000118 | inferred from biological aspect of ancestor with PANTHER:PTN000328752 histone deacetylase complex ; GO:0000118 | inferred from sequence or structural similarity with UniProtKB:O75446 "Sap30, CG4756, cg4756, SAP30" "IPR025717:Histone deacetylase complex subunit SAP30 zinc-finger, IPR025718:Histone deacetylase complex subunit SAP30, Sin3 binding domain, IPR024145:Histone deacetylase complex subunit SAP30/SAP30-like" CG4756 11-Aug-17 DroID_v2017_08 Drer\sap30l Scer\SAP30 - "Xtro\sap30, Xtro\sap30l" "Mmus\Sap30, Mmus\Sap30l" "Hsap\SAP30, Hsap\SAP30L" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0259970 Sfp70A4 Seminal fluid protein 70A4 http://flybase.org/reports/FBgn0259970 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp70A4, CG42480" - CG42480 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025340 anon-58Fc anon-58Fc http://flybase.org/reports/FBgn0025340 - gene - - - "11-2, anon-58Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032246 CG5168 - http://flybase.org/reports/FBgn0032246 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 - - CG5168 "IPR000306:FYVE zinc finger, IPR001680:WD40 repeat, IPR011011:Zinc finger, FYVE/PHD-type, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017455:Zinc finger, FYVE-related, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5168 11-Aug-17 DroID_v2017_08 "Drer\wdfy2, Drer\wdfy1" "Scer\VPS27, Scer\TEX1, Scer\GGA1, Scer\LSB5, Scer\GGA2" "Cele\ZK632.12, Cele\wdfy-2" "Xtro\wdfy2, Xtro\wdfy1" "Mmus\Wdfy1, Mmus\Wdfy2" "Hsap\WDFY1, Hsap\WDFY2" viable heart primordium DRSC29755 K -0.493664356 -0.052151597 0.220216004 -0.164776876 0.236567151 1.689598136 FBgn0043350 EP3474 EP3474 http://flybase.org/reports/FBgn0043350 gene - - - EP3474 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "scutellar bristle,ectopic,dorsocentral bristle,tormogen cell" FBgn0032066 LManIII Lysosomal alpha-mannosidase III http://flybase.org/reports/FBgn0032066 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR015341 alpha-mannosidase activity ; GO:0004559 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 mannose metabolic process ; GO:0006013 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 protein deglycosylation ; GO:0006517 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 - "LManIII, CG9463" "IPR000602:Glycoside hydrolase family 38, N-terminal domain, IPR011013:Galactose mutarotase-like domain, IPR011682:Glycosyl hydrolase family 38, C-terminal, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR015341:Glycoside hydrolase family 38, central domain, IPR027291:Glycoside hydrolase 38/57, N-terminal domain, IPR028995:Glycoside hydrolase families 57/38, central domain" CG9463 11-Aug-17 DroID_v2017_08 "Drer\man2b2, Drer\man2a2, Drer\man2b1" - Cele\aman-1 "Xtro\man2a2, Xtro\man2b1, Xtro\man2b2, Xtro\man2a1" "Mmus\Man2a1, Mmus\Man2b1, Mmus\Man2b2" "Hsap\MAN2A2, Hsap\MAN2B1, Hsap\MAN2B2, Hsap\MAN2A1" viable FBgn0086395 BG02209 - http://flybase.org/reports/FBgn0086395 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02209 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0261561 CG42675 - http://flybase.org/reports/FBgn0261561 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42675, anon-WO0140519.247, CG10999, CG31554" IPR026319:Zinc finger C2HC domain-containing protein CG42675 11-Aug-17 DroID_v2017_08 "Drer\zc2hc1a, Drer\zc2hc1c" - Cele\T03G11.3 "Xtro\zc2hc1c, Xtro\zc2hc1a" "Mmus\Zc2hc1a, Mmus\Zc2hc1c, Mmus\Zc2hc1b" "Hsap\ZC2HC1C, Hsap\ZC2HC1A, Hsap\ZC2HC1B" DRSC12157 E -0.314297088 -0.300112246 -1.618046608 0.34588869 -0.20862948 -0.314250778 FBgn0025571 SF1 Splicing factor 1 http://flybase.org/reports/FBgn0025571 FBgn0038518 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 pre-mRNA branch point binding ; GO:0045131 | inferred from electronic annotation with InterPro:IPR031150 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:12950 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004106 inferred from sequence or structural similarity with protein_id:CAA03883 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000004106 inferred from sequence or structural similarity with protein_id:CAA03883 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "dSF1, CG5836, cg5836, p70, SF1" "IPR001878:Zinc finger, CCHC-type, IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR031150:BBP/SF1 family, IPR032570:Splicing factor 1, helix-hairpin domain" CG5836 11-Aug-17 DroID_v2017_08 Drer\sf1 Scer\MSL5 Cele\sfa-1 Xtro\sf1 Mmus\Sf1 Hsap\SF1 "behavior defective,recessive,viable,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0029949 CG15035 - http://flybase.org/reports/FBgn0029949 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000001118 phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000001118 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence model protein dephosphorylation ; GO:0006470 | inferred by curator from GO:0004722 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000001118 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000268440 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000001118 CG15035 IPR001932:PPM-type phosphatase domain CG15035 11-Aug-17 DroID_v2017_08 "Drer\pptc7a, Drer\pptc7b" Scer\PTC7 Cele\W09D10.4 Xtro\pptc7 Mmus\Pptc7 Hsap\PPTC7 viable FBgn0040072 snRNP-U1-70K::Hsap\SRSF1 SFRS1 http://flybase.org/reports/FBgn0040072 engineered_fusion_gene - - - "U1-70K, snRNP70K::Hsap\SFRS1, snRNP-U1-70K::Hsap\SFRS1, snRNP-U1-70K::Hsap\SRSF1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060384 l(3)S134415b lethal (3) S134415b http://flybase.org/reports/FBgn0060384 gene - - - "1344/15, l(3)S134415b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033579 CG13229 - http://flybase.org/reports/FBgn0033579 protein_coding_gene G-protein coupled peptide receptor activity ; GO:0008528 | inferred from electronic annotation with InterPro:IPR019427 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "anon-WO0170980.143, anon-WO0170980.142, CG13229, Dm CG13229" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM, IPR019427:7TM GPCR, serpentine receptor class w (Srw)" CG13229 11-Aug-17 DroID_v2017_08 "Drer\gper1, Drer\nmur1b, Drer\adra1ba, Drer\gpr142" - "Cele\srw-42, Cele\srw-120, Cele\srw-22, Cele\dmsr-11, Cele\srw-77, Cele\srw-15, Cele\srw-33, Cele\M03F8.7, Cele\srw-54, Cele\srw-130, Cele\srw-26, Cele\srw-62, Cele\srw-90, Cele\srw-73, Cele\srw-100, Cele\srw-123, Cele\srw-121, Cele\srw-59, Cele\srw-29, Cele\srw-3, Cele\srw-136, Cele\dmsr-10, Cele\egl-6, Cele\srw-36, Cele\Y75B12B.10, Cele\srw-40, Cele\srw-91, Cele\dmsr-3, Cele\dmsr-1, Cele\C25F9.13, Cele\srw-13, Cele\srw-7, Cele\srw-87, Cele\srw-38, Cele\srw-51, Cele\srw-55, Cele\srw-9, Cele\srw-16, Cele\srw-72, Cele\dmsr-7, Cele\srw-122, Cele\K01A6.6, Cele\srw-39, Cele\srw-53, Cele\srw-99, Cele\srw-12, Cele\F13H6.5, Cele\srw-129, Cele\dmsr-4, Cele\srw-8, Cele\srw-20, Cele\dmsr-2, Cele\srw-57, Cele\srw-108, Cele\srw-14, Cele\srw-112, Cele\srw-56, Cele\T27C5.10, Cele\Y70C5A.4, Cele\srw-1, Cele\srw-61, Cele\C47E8.3, Cele\srw-44, Cele\srw-6, Cele\srw-66, Cele\sprr-3, Cele\srw-10, Cele\srw-79, Cele\srw-75, Cele\srw-95, Cele\frpr-7, Cele\srw-84, Cele\srw-140, Cele\srw-76, Cele\T26H8.4, Cele\srw-145, Cele\srw-34, Cele\srw-35, Cele\srw-68, Cele\srw-98, Cele\srw-24, Cele\srw-143, Cele\srw-115, Cele\frpr-13, Cele\C09F12.3, Cele\srw-2, Cele\T02D1.4, Cele\dmsr-15, Cele\srw-109, Cele\srw-88, Cele\srw-133, Cele\srw-139, Cele\F38E1.6, Cele\dmsr-16, Cele\dmsr-13, Cele\srw-4, Cele\srw-23, Cele\srw-97, Cele\srw-119, Cele\C41G6.16, Cele\srw-102, Cele\srw-19, Cele\srw-63, Cele\srw-21, Cele\srw-69, Cele\F09C6.16, Cele\T26H8.5, Cele\srw-107, Cele\srw-11, Cele\dmsr-6, Cele\srw-142, Cele\srw-101, Cele\srw-30, Cele\srw-83, Cele\dmsr-5, Cele\srw-85, Cele\srw-117, Cele\srw-82, Cele\srw-43, Cele\srw-103, Cele\srw-118, Cele\srw-31, Cele\srw-141, Cele\srw-60, Cele\srw-17, Cele\M01G12.6, Cele\srw-113, Cele\srw-137, Cele\srw-127, Cele\srw-124, Cele\dmsr-8, Cele\srw-67, Cele\srw-134, Cele\srw-94, Cele\srw-41, Cele\srw-144, Cele\srw-71, Cele\srw-48, Cele\srw-111, Cele\dmsr-14, Cele\dmsr-12, Cele\srw-89, Cele\srw-32, Cele\dmsr-9, Cele\srw-138" - "Mmus\Gpr139, Mmus\Gpr142, Mmus\Cysltr1" "Hsap\GPR142, Hsap\P2RY10, Hsap\GPR139" FBgn0038526 CG14327 - http://flybase.org/reports/FBgn0038526 protein_coding_gene - - - "BcDNA:RE25364, CG14327" - CG14327 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC14806 K -0.313426307 0.501895224 -0.231652026 -0.13648468 -1.589706757 -0.985903154 FBgn0011168 l(1)DM-5 lethal (1) DM-5 http://flybase.org/reports/FBgn0011168 FBgn0010204 gene - - - l(1)DM-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016006 l(3)63Ee lethal (3) 63Ee http://flybase.org/reports/FBgn0016006 - gene - - - "l(3)SH1, l(3)63Ee" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039640 CG14516 - http://flybase.org/reports/FBgn0039640 protein_coding_gene peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 CG14516 "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG14516 11-Aug-17 DroID_v2017_08 "Drer\erap2, Drer\lnpep, Drer\npepps, Drer\erap1b, Drer\si:ch211-276a23.5, Drer\enpep, Drer\si:ch211-106j24.1, Drer\anpepa, Drer\si:ch211-198g19.1, Drer\LOC100004744, Drer\erap1a, Drer\anpepb, Drer\si:ch211-149p5.1" "Scer\AAP1, Scer\TMA108, Scer\APE2" "Cele\F49B2.6, Cele\VB0395L.1, Cele\Y53F4B.20, Cele\T12E12.6, Cele\pam-1, Cele\R03G8.4, Cele\taf-2, Cele\Y42A5A.1, Cele\AC3.5, Cele\T16G12.1, Cele\T07F10.1, Cele\R03G8.6, Cele\mnp-1, Cele\Y67D8C.9" "Xtro\npepps, Xtro\anpep, Xtro\lnpep, Xtro\lvrn, Xtro\erap1, Xtro\enpep" "Mmus\Anpep, Mmus\Enpep, Mmus\Npepps, Mmus\Lnpep, Mmus\Lvrn, Mmus\Trhde, Mmus\Erap1" "Hsap\NPEPPS, Hsap\ERAP1, Hsap\ERAP2, Hsap\LVRN, Hsap\TRHDE, Hsap\LNPEP, Hsap\ANPEP, Hsap\ENPEP" viable FBgn0038357 CG5623 - http://flybase.org/reports/FBgn0038357 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT10995, CG5623" IPR009961:Protein of unknown function DUF1487 CG5623 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051660 smog smog http://flybase.org/reports/FBgn0051660 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mGluR convergent extension involved in gastrulation ; GO:0060027 | inferred from mutant phenotype apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype regulation of gastrulation ; GO:0010470 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mGluR establishment or maintenance of cytoskeleton polarity involved in gastrulation ; GO:0003380 | inferred from mutant phenotype regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype regulation of myosin II filament organization ; GO:0043519 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from biological aspect of ancestor with PANTHER:PTN002091395 mesectoderm development ; GO:0048383 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN002091395 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with mGluR "CG31660, CG11923, CG11925, anon-WO0170980.182, anon-WO0170980.181, smog, pog" "IPR017978:GPCR family 3, C-terminal" CG31660 11-Aug-17 DroID_v2017_08 "Drer\gpr158a, Drer\si:ch211-156l18.8, Drer\gpr158b" - Cele\F39B2.8 Xtro\gpr158 "Mmus\Gpr179, Mmus\Gpr158" "Hsap\GPR158, Hsap\GPR179" viable embryo FBgn0011270 Pglym87 Pglym87 http://flybase.org/reports/FBgn0011270 FBgn0038004 protein_coding_gene "2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity ; GO:0046538 | inferred from biological aspect of ancestor with PANTHER:PTN000231842" glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 regulation of pentose-phosphate shunt ; GO:0043456 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 gluconeogenesis ; GO:0006094 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 "CG17645, pglym87, Pglym, Pglym87" "IPR001345:Phosphoglycerate/bisphosphoglycerate mutase, active site, IPR005952:Phosphoglycerate mutase 1, IPR013078:Histidine phosphatase superfamily, clade-1, IPR029033:Histidine phosphatase superfamily" CG17645 11-Aug-17 DroID_v2017_08 "Drer\pgam1a, Drer\tigara, Drer\bpgm, Drer\pgam1b, Drer\pgam2" "Scer\GPM3, Scer\GPM2, Scer\GPM1" - "Xtro\bpgm, Xtro\pgam1, Xtro\pgam2" "Mmus\Pgam2, Mmus\Pgam1, Mmus\Bpgm" "Hsap\BPGM, Hsap\PGAM4, Hsap\PGAM2, Hsap\PGAM1" viable FBgn0002091 l(2)57Ba lethal (2) 57Ba http://flybase.org/reports/FBgn0002091 - gene - - - l(2)57Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004201 l(3)84Dc lethal (3) 84Dc http://flybase.org/reports/FBgn0004201 - gene - - - l(3)84Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266241 CR44936 - http://flybase.org/reports/FBgn0266241 non_protein_coding_gene - - - "CR44936, lincRNA.722" - CR44936 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011059 l(1)Q12 lethal (1) Q12 http://flybase.org/reports/FBgn0011059 FBgn0010210 gene - - - l(1)Q12 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001636 l(1)dn16 lethal (1) discs normal 16 http://flybase.org/reports/FBgn0001636 - gene - - - "l(1)d.norm.-16, l(1)dn16" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0051292 CR31292 - http://flybase.org/reports/FBgn0051292 pseudogene_attribute - - - "CG31292, CR31292" - CR31292 11-Aug-17 DroID_v2017_08 - - - - - - DRSC13120 E -0.505822752 0.114989139 3.121391905 0.220332354 -0.309384024 0.384903647 FBgn0036857 CG9629 - http://flybase.org/reports/FBgn0036857 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR029510" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163, InterPro:IPR029510" - CG9629 "IPR015590:Aldehyde dehydrogenase domain, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR029510:Aldehyde dehydrogenase, glutamic acid active site" CG9629 11-Aug-17 DroID_v2017_08 Drer\aldh7a1 "Scer\ALD4, Scer\ALD6" Cele\alh-9 Xtro\aldh7a1 Mmus\Aldh7a1 Hsap\ALDH7A1 viable FBgn0266056 Su(var)211 - http://flybase.org/reports/FBgn0266056 gene - - - "Su(var)211, 211" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0034667 comr cookie monster http://flybase.org/reports/FBgn0034667 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000232 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000232 protein binding ; GO:0005515 | inferred from physical interaction with tomb protein binding ; GO:0005515 | inferred from physical interaction with wuc protein binding ; GO:0005515 | inferred from physical interaction with topi" spermatogenesis ; GO:0007283 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype transcriptionally active chromatin ; GO:0035327 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG13493, zab, Z2-1340, comr, Comr" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR000232:Heat shock factor (HSF)-type, DNA-binding" CG13493 11-Aug-17 DroID_v2017_08 - - - - - - viable "testis,meiotic cell cycle,spermatid" FBgn0016038 Vsp37A Vacuolar protein sorting 37A http://flybase.org/reports/FBgn0016038 "FBgn0025636, FBgn0045872" protein_coding_gene molecular_function ; GO:0003674 | no biological data available ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from sequence or structural similarity with SGD:S000004109 ESCRT I complex ; GO:0000813 | inferred from sequence or structural similarity with SGD:S000004109 "EG:115C2.5, CG17828, anon-WO0153538.78, vps37A, Vps37, Vsp37A, mod(r)" "IPR009851:Modifier of rudimentary, Modr" CG17828 11-Aug-17 DroID_v2017_08 "Drer\vps37a, Drer\vps37c, Drer\zgc:114173, Drer\vps37b, Drer\si:ch211-284f22.3" Scer\SRN2 Cele\vps-37 "Xtro\vps37a, Xtro\vps37b" "Mmus\Vps37d, Mmus\Vps37c, Mmus\Vps37a, Mmus\Vps37b" "Hsap\VPS37B, Hsap\VPS37A, Hsap\VPS37C, Hsap\VPS37D" " adult stage | male , adult stage | female " viable wing DRSC18794 I 1.972783565 1.350211448 -0.485607733 -0.112675819 0.026519377 -0.376289769 FBgn0052741 CG32741 - http://flybase.org/reports/FBgn0052741 protein_coding_gene - - - CG32741 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261504 7SLRNA:CR42652 Signal recognition particle 7SL RNA CR42652 http://flybase.org/reports/FBgn0261504 non_protein_coding_gene - - - "7SL RNA, 7SLRNA:CR42652, CR42652, 7SLRNA" - CR42652 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029971 ND-MNLL NADH dehydrogenase (ubiquinone) MNLL subunit http://flybase.org/reports/FBgn0029971 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O75438 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O75438" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O75438 "CG15328, CG18624, Dromel_CG18624_FBtr0071140_mORF, NINM, ND-MNLL" "IPR012575:NADH:ubiquinone oxidoreductase, MNLL subunit" CG18624 11-Aug-17 DroID_v2017_08 - - - - - Hsap\NDUFB1 "viable,visible,lethal,partially lethal - majority die,some die during pupal stage,heat sensitive" "trichogen cell,mesothoracic tergum" FBgn0060699 l(3)S071814b lethal (3) S071814b http://flybase.org/reports/FBgn0060699 gene - - - "0718/14, l(3)S071814b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0069137 mcl(3)Z5860 mcl(3)Z5860 http://flybase.org/reports/FBgn0069137 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z5860 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0004803 fs(2)ltoWi42 female sterile (2) ltoWi42 http://flybase.org/reports/FBgn0004803 - gene molecular_function ; GO:0003674 | no biological data available dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoWi42 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0005181 l(2)S3a lethal of Seto 3a http://flybase.org/reports/FBgn0005181 - gene - - - l(2)S3a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0036286 CG10616 - http://flybase.org/reports/FBgn0036286 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay CG10616 IPR029454:ODR-4-like CG10616 11-Aug-17 DroID_v2017_08 Drer\c2h1orf27 - Cele\odr-4 Xtro\c1orf27 Mmus\BC003331 Hsap\C1orf27 "viable,body color defective" mesothoracic tergum FBgn0051099 CG31099 - http://flybase.org/reports/FBgn0051099 protein_coding_gene - - - "CG10551, CG31099" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31099 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.8, Cele\F59B1.10" - - - "partially lethal - majority die,some die during pupal stage" FBgn0267905 CG46193 - http://flybase.org/reports/FBgn0267905 protein_coding_gene - sperm chromatin condensation ; GO:0035092 | inferred from electronic annotation with InterPro:IPR024460 - CG46193 "IPR024460:Protamine-like, IPR009071:High mobility group box domain" CG46193 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036165 chrb charybde http://flybase.org/reports/FBgn0036165 protein_coding_gene - negative regulation of signal transduction ; GO:0009968 | inferred from electronic annotation with InterPro:IPR012918 cell death ; GO:0008219 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype regulation of TOR signaling ; GO:0032006 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from genetic interaction with scyl apoptotic process ; GO:0006915 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9NX09 "char, EP(3)1035, clone 2.51, anon-EST:Liang-2.51, CG7533, BcDNA:GH09771, chrb, Charybde" IPR012918:RTP801-like CG7533 11-Aug-17 DroID_v2017_08 Drer\ddit4 - - Xtro\ddit4 "Mmus\Ddit4l, Mmus\Ddit4" "Hsap\DDIT4, Hsap\DDIT4L" "viable,fertile,long lived,stress response defective,recessive,decreased cell size,somatic clone" DRSC11335 I -1.754643025 0.638436099 -0.162952858 0.493145625 0.430228617 -0.080297201 FBgn0082163 splo splotchy http://flybase.org/reports/FBgn0082163 gene - - - splo - - 11-Aug-17 DroID_v2017_08 - - - - - - "hemocyte,supernumerary,lamellocyte" FBgn0016818 l(1)L4 lethal (1) L4 http://flybase.org/reports/FBgn0016818 - gene - - - "l(1)L4, L4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069164 mcl(3)Z1550 mcl(3)Z1550 http://flybase.org/reports/FBgn0069164 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1550 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0029945 CG18155 - http://flybase.org/reports/FBgn0029945 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - "FBgn0029945, CG18155" "IPR000873:AMP-dependent synthetase/ligase, IPR025110:AMP-binding enzyme C-terminal domain" CG18155 11-Aug-17 DroID_v2017_08 "Drer\acsf3, Drer\acsf2" Scer\PCS60 "Cele\acs-21, Cele\acs-11, Cele\acs-1, Cele\acs-14" Xtro\acsf3 "Mmus\Acsf3, Mmus\Acsf2" "Hsap\ACSF2, Hsap\ACSF3" partially lethal - majority die FBgn0266329 CR44994 - http://flybase.org/reports/FBgn0266329 non_protein_coding_gene - - - CR44994 - CR44994 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027143 l(3)71DEd lethal (3) 71DEd http://flybase.org/reports/FBgn0027143 - gene - - - l(3)71DEd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0001890 l(2)21Dd lethal (2) 21Dd http://flybase.org/reports/FBgn0001890 - gene - - - "l(2)neh-4, l(2)neh4, l(2)21Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010345 Mst75Ca Male-specific RNA 75Ca http://flybase.org/reports/FBgn0010345 FBgn0002861 gene - - - "Mst75C, mst-2, mst(3)ag-2, mst(3)ag-15A, Mst75Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014084 anon-20ABa anon-20ABa http://flybase.org/reports/FBgn0014084 - gene - - - anon-20ABa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025925 l(3)76BDd lethal (3) 76BDd http://flybase.org/reports/FBgn0025925 - gene - - - l(3)76BDd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260261 GSd239 - http://flybase.org/reports/FBgn0260261 gene - - - GSd239 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0082912 alpha-Spec::Actn alpha-Spec::Actn http://flybase.org/reports/FBgn0082912 engineered_fusion_gene - - - alpha-Spec::Actn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025556 anon-88Bb anon-88Bb http://flybase.org/reports/FBgn0025556 - gene - - - "c5.5, anon-88Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265865 CR44654 - http://flybase.org/reports/FBgn0265865 non_protein_coding_gene - - - "lincRNA.988, CR44654" - CR44654 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015409 l(1)12Ca lethal (1) 12Ca http://flybase.org/reports/FBgn0015409 - gene - - - l(1)12Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264486 CG43894 - http://flybase.org/reports/FBgn0264486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43894, CG14119, BP1086, HDC09916, CG34032" - CG43894 11-Aug-17 DroID_v2017_08 - - - - - - DRSC10123 IEK -0.241478584 -4.03319601 -0.647967371 -3.097112215 -2.235849481 -2.89281772 FBgn0002653 mat(2)cell-B maternal effect cellularisation defect B http://flybase.org/reports/FBgn0002653 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)cellPH65, mat(2)cell-B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0028379 fan farinelli http://flybase.org/reports/FBgn0028379 protein_coding_gene - sperm individualization ; GO:0007291 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR016763 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "fan, CG7919" "IPR000535:Major sperm protein (MSP) domain, IPR008962:PapD-like, IPR016763:Vesicle-associated membrane-protein-associated protein, IPR013783:Immunoglobulin-like fold" CG7919 11-Aug-17 DroID_v2017_08 "Drer\vapb, Drer\vapal, Drer\vapa" "Scer\SCS22, Scer\SCS2" "Cele\F57A10.2, Cele\W08E3.4, Cele\F58E6.5, Cele\Y116A8A.2, Cele\F42G2.5, Cele\F54H5.3, Cele\ZC196.2, Cele\Y38F2AR.10, Cele\Y53C10A.15, Cele\F52F12.8, Cele\vpr-1, Cele\Y116A8A.7" "Xtro\mospd2, Xtro\mospd3, Xtro\vapb, Xtro\vapa" "Mmus\Vapa, Mmus\Vapb, Mmus\Mospd3" "Hsap\VAPA, Hsap\VAPB, Hsap\MOSPD3" "viable,fertile,semi-sterile" cystic bulge FBgn0035071 CG15859 - http://flybase.org/reports/FBgn0035071 protein_coding_gene - - - CG15859 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025642 CG32812 - http://flybase.org/reports/FBgn0025642 FBgn0052812 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with HGNC:17433 negative regulation of phosphatase activity ; GO:0010923 | inferred from sequence or structural similarity with HGNC:17433 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:17433 "EG:114D9.1, CG11408, CG32812" "IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG32812 11-Aug-17 DroID_v2017_08 "Drer\chp1, Drer\tescb, Drer\LOC100536377, Drer\chp2, Drer\ppp3r1b, Drer\daam1a, Drer\daam1b, Drer\tesca, Drer\ppp3r1a" Scer\CNB1 "Cele\chpf-1, Cele\chpf-2, Cele\T03F1.11, Cele\daam-1, Cele\pbo-1" "Xtro\daam1, Xtro\cib1, Xtro\chp1, Xtro\ppp3r1" "Mmus\Chp1, Mmus\Daam2, Mmus\Chp2, Mmus\Tesc, Mmus\Daam1, Mmus\Cib4, Mmus\Tescl, Mmus\Ppp3r1, Mmus\Cib1, Mmus\Ppp3r2" "Hsap\CIB4, Hsap\PPP3R2, Hsap\DAAM1, Hsap\CIB1, Hsap\DAAM2, Hsap\CHP2, Hsap\TESC, Hsap\PPP3R1, Hsap\CHP1" viable FBgn0005331 pil3 pilosus on chromosome 3 http://flybase.org/reports/FBgn0005331 - gene - - - "pil-3, pil3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semidominant" abdominal sternite 6 FBgn0266360 CR45008 - http://flybase.org/reports/FBgn0266360 non_protein_coding_gene - - - CR45008 - CR45008 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083238 EP2494 EP2494 http://flybase.org/reports/FBgn0083238 gene - - - EP2494 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065140 l(3)SH106 lethal (3) SH106 http://flybase.org/reports/FBgn0065140 gene - - - "l(3)SH106, l(2)SH3 106" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015452 l(1)9Fl lethal (1) 9Fl http://flybase.org/reports/FBgn0015452 - gene - - - l(1)9Fl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0267113 CR45553 - http://flybase.org/reports/FBgn0267113 non_protein_coding_gene - - - CR45553 - CR45553 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267354 X-141 - http://flybase.org/reports/FBgn0267354 nuclear_gene - - - "X-141, Gene_X_141" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043884 mask multiple ankyrin repeats single KH domain http://flybase.org/reports/FBgn0043884 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 protein kinase binding ; GO:0019901 | inferred from physical interaction with UniProtKB:A8DYP0 antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype negative regulation of mitophagy ; GO:1903147 | inferred from mutant phenotype inferred from genetic interaction with Atg18a transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from genetic interaction with csw inferred from genetic interaction with Ras85D inferred from genetic interaction with sev negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with csw centrosome duplication ; GO:0051298 | inferred from mutant phenotype M band ; GO:0031430 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG6268, CG6313, cg6313, CG18671, CG31138, CG33106, mask, MASK, EC3-6, Mask" "IPR002110:Ankyrin repeat, IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR020683:Ankyrin repeat-containing domain, IPR011989:Armadillo-like helical" CG33106 11-Aug-17 DroID_v2017_08 "Drer\ankhd1, Drer\ankrd22" Scer\HOS4 "Cele\C45B2.6, Cele\R11A8.7" "Xtro\ankhd1, Xtro\ankrd17" "Mmus\Ankhd1, Mmus\Ankrd22, Mmus\Ankrd17" "Hsap\ANKRD17, Hsap\ANKRD22, Hsap\ANKHD1-EIF4EBP3, Hsap\ANKHD1, Hsap\EIF4EBP3" "viable,fertile,visible,small body,increased cell death,lethal - all die before end of larval stage,some die during larval stage,recessive,somatic clone,body color defective,partially lethal - majority die,some die during pupal stage" "eye,heart primordium,eye-antennal disc,ommatidial precursor cluster,embryonic/larval digestive system,photoreceptor cell,somatic clone,photoreceptor cell R7,eye photoreceptor cell,photoreceptor cell R1,photoreceptor cell R6,dorsal appendage,trichogen cell,mesothoracic tergum" DRSC25063 K -0.259530412 0.354541624 -0.478333527 -0.63078145 0.237097569 2.26080927 FBgn0264570 CR43942 - http://flybase.org/reports/FBgn0264570 non_protein_coding_gene - - - CR43942 - CR43942 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010182 tu(2)D tu(2)D http://flybase.org/reports/FBgn0010182 - gene - - - tu(2)D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038531 CG14325 - http://flybase.org/reports/FBgn0038531 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14325 IPR001611:Leucine-rich repeat CG14325 11-Aug-17 DroID_v2017_08 "Drer\lrrc74b, Drer\lrrc34, Drer\tcte1" - - "Xtro\tcte1, Xtro\lrrc34, Xtro\LOC100485518" "Mmus\Lrrc74b, Mmus\Lrrc34, Mmus\Tcte1, Mmus\Lrrc74a" "Hsap\LRRC34, Hsap\LRRC74B, Hsap\LRRC74A, Hsap\TCTE1" "viable,fertile" FBgn0069999 BG01613 BG01613 http://flybase.org/reports/FBgn0069999 gene - - - BG01613 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0263515 mir-4983 mir-4983 stem loop http://flybase.org/reports/FBgn0263515 miRNA_gene - - - "mir-4983, CR43500, dme-mir-4983" - CR43500 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044501 Cyp450_U5csm Cyp450_U5csm http://flybase.org/reports/FBgn0044501 gene thiamine pyrophosphate binding ; GO:0030976 | inferred from electronic annotation with InterPro:IPR000399 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR000399 - - "DU5csm, Cyp450_U5csm" "IPR000399:TPP-binding enzyme, conserved site" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001457 l(1)7Dk lethal (1) 7Dk http://flybase.org/reports/FBgn0001457 - gene - - - l(1)7Dk - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0058303 CG40303 - http://flybase.org/reports/FBgn0058303 protein_coding_gene - - - CG40303 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002198 l(3)67Ab lethal (3) 67Ab http://flybase.org/reports/FBgn0002198 - gene - - - l(3)67Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0040138 l(1)G0493 lethal (1) G0493 http://flybase.org/reports/FBgn0040138 gene - - - l(1)G0493 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002428 l(3)F34 lethal (3) F34 http://flybase.org/reports/FBgn0002428 - gene - - - "l(3)34, l(3)F34" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" wing FBgn0002296 l(3)80Fg lethal (3) 80Fg http://flybase.org/reports/FBgn0002296 - gene - - - "l4A, l(3)Lh4A, l(3)80Fg, 80Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037027 HIPP1 HP1 and insulator partner protein 1 http://flybase.org/reports/FBgn0037027 protein_coding_gene enoyl-CoA hydratase activity ; GO:0004300 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000941570 "CG3680, HIPP1" "IPR001753:Crotonase superfamily, IPR029045:ClpP/crotonase-like domain" CG3680 11-Aug-17 DroID_v2017_08 "Drer\zgc:92030, Drer\cdyl, Drer\echs1" "Scer\DCI1, Scer\EHD3, Scer\ECI1" "Cele\ech-7, Cele\ech-6" Xtro\eci2 "Mmus\Cdyl2, Mmus\Eci3, Mmus\Cdyl, Mmus\Echs1, Mmus\Eci2" "Hsap\CDYL2, Hsap\CDY2B, Hsap\CDY2A, Hsap\ECI2, Hsap\CDY1B, Hsap\CDYL, Hsap\CDY1, Hsap\ECHS1" viable FBgn0267689 CG46025 - http://flybase.org/reports/FBgn0267689 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG46025, CG7196, CG14538" - CG46025 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262426 mir-283 mir-283 stem loop http://flybase.org/reports/FBgn0262426 miRNA_gene - positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype - "miR-283, mir-283, Dme-miR-283, dme-mir-283, 283, CR42980, miR283, CR33599, dme-miR-283" - CR42980 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037229 CG9766 - http://flybase.org/reports/FBgn0037229 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG9766 "IPR002110:Ankyrin repeat, IPR003961:Fibronectin type III, IPR020683:Ankyrin repeat-containing domain" CG9766 11-Aug-17 DroID_v2017_08 Drer\fank1 - - Xtro\fank1 Mmus\Fank1 Hsap\FANK1 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0004997 cr-a cream a http://flybase.org/reports/FBgn0004997 - gene - - - cr-a - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0264958 CR44127 - http://flybase.org/reports/FBgn0264958 non_protein_coding_gene - - - "lincRNA.253, CR44127" - CR44127 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051040 Cog7 Cog7 http://flybase.org/reports/FBgn0051040 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR019335 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000484904 Golgi organization ; GO:0007030 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000002973 male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype" Golgi transport complex ; GO:0017119 | inferred from direct assay acroblast ; GO:0036063 | inferred from direct assay Golgi apparatus ; GO:0005794 | colocalizes_with inferred from sequence or structural similarity with UniProtKB:P83436 Golgi apparatus ; GO:0005794 | inferred from direct assay "CG7880, CG31040, Cog7" IPR019335:Conserved oligomeric Golgi complex subunit 7 CG31040 11-Aug-17 DroID_v2017_08 Drer\cog7 - - Xtro\cog7 Mmus\Cog7 Hsap\COG7 "viable,male sterile,cytokinesis defective,male" "spermatid,contractile ringBSC861),Golgi stack,spermatocyte,acroblast,spermatid axoneme,onion stage spermatid" FBgn0024669 l(2)k03901 lethal (2) k03901 http://flybase.org/reports/FBgn0024669 - gene - - - "39/1, l(2)k03901" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0058131 CG40131 - http://flybase.org/reports/FBgn0058131 protein_coding_gene - - - CG40131 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046838 l(3)A4-4L5 lethal (3) A4-4L5 http://flybase.org/reports/FBgn0046838 gene - - - l(3)A4-4L5 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010367 dsx-c35A doublesex cognate 35A http://flybase.org/reports/FBgn0010367 - gene - - - "dsx-c35, dsx-c35A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034996 CG13575 - http://flybase.org/reports/FBgn0034996 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled peptide receptor activity ; GO:0008528 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "anon-WO0170980.149, anon-WO0170980.148, CG13575" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG13575 11-Aug-17 DroID_v2017_08 "Drer\tacr1a, Drer\tacr3a, Drer\tacr3l, Drer\LOC100333270, Drer\tacr1b, Drer\tacr2" - "Cele\gnrr-7, Cele\npr-35" "Xtro\tacr3, Xtro\tacr1" "Mmus\Tacr1, Mmus\Tacr2, Mmus\Tacr3" "Hsap\TACR2, Hsap\TACR3, Hsap\TACR1" "viable,visible" "chaeta,supernumerary" DRSC22851 K 0.46446077 0.800247558 0.826322345 0.759144202 0.67557251 3.932458349 FBgn0001295 k kidney http://flybase.org/reports/FBgn0001295 - gene - - - k - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,viable" "arista,eye,antenna,vibrissae" FBgn0000215 broadened broadened http://flybase.org/reports/FBgn0000215 - gene - - - "broadened, brd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0016044 ms(3)ods male sterile (3) only diploid stages http://flybase.org/reports/FBgn0016044 - gene - - - ms(3)ods - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266843 CR45305 - http://flybase.org/reports/FBgn0266843 non_protein_coding_gene - - - CR45305 - CR45305 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030187 Ipod Interaction partner of Dnmt2 http://flybase.org/reports/FBgn0030187 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "IPOD, CG2961, Ipod" IPR031903:Domain of unknown function DUF4766 CG2961 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083045 snoRNA:Psi18S-1389b snoRNA:Psi18S-1389b http://flybase.org/reports/FBgn0083045 snoRNA_gene - - - "snoRNA:Psi18S-1389b, psi18s-1389b, CR34557" - CR34557 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000260 cast ojos castanos http://flybase.org/reports/FBgn0000260 - gene - - - cast - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" pigment cell FBgn0051441 CG31441 - http://flybase.org/reports/FBgn0051441 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG5135, CG31441" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31441 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-221f6.1, Drer\zgc:174928, Drer\znf408, Drer\si:ch211-191d2.2, Drer\bcl6ab" "Scer\ZAP1, Scer\AZF1" "Cele\Y55F3AM.14, Cele\M03D4.4, Cele\ztf-23, Cele\lin-29, Cele\blmp-1" - "Mmus\Zfp12, Mmus\Zfp93, Mmus\Zfp708, Mmus\Zscan5b, Mmus\Zfp445, Mmus\Zfp24, Mmus\Zfp945, Mmus\Zfp984, Mmus\Zfp369, Mmus\Rbak, Mmus\Zfp110, Mmus\Zfp810, Mmus\Gm13212, Mmus\Zfp62, Mmus\Zfp612" "Hsap\ZNF8, Hsap\ZNF233, Hsap\ZNF98, Hsap\ZNF850, Hsap\ZNF480, Hsap\ZNF527, Hsap\ZNF816, Hsap\ZNF160, Hsap\ZNF558, Hsap\ZNF792, Hsap\ZNF560, Hsap\ZNF43, Hsap\ZNF568, Hsap\ZNF70, Hsap\ZNF708, Hsap\ZNF117, Hsap\ZNF595, Hsap\ZNF528, Hsap\ZNF675, Hsap\ZNF570, Hsap\ZNF492, Hsap\ZNF211, Hsap\ZNF254, Hsap\ZNF761, Hsap\ZNF28, Hsap\ZNF681, Hsap\ZNF721, Hsap\ZNF730, Hsap\ZNF572, Hsap\ZSCAN30, Hsap\ZNF784, Hsap\ZFP28, Hsap\ZNF582, Hsap\ZNF845, Hsap\RBAK-RBAKDN, Hsap\ZNF468, Hsap\ZNF485" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC27463 K 1.489355368 -0.358978521 -0.180885701 -0.001648519 0.35700909 1.744619339 FBgn0069107 mus317 mutagen-sensitive 317 http://flybase.org/reports/FBgn0069107 gene - - - mus317 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0026269 anon-X2 anon-X2 http://flybase.org/reports/FBgn0026269 - gene - - - "X2, anon-X2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038277 RpS5b Ribosomal protein S5b http://flybase.org/reports/FBgn0038277 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR005716, InterPro:IPR020606 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR020606 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000235, InterPro:IPR005716, InterPro:IPR020606 cytoplasmic translation ; GO:0002181 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype" small ribosomal subunit ; GO:0015935 | inferred from electronic annotation with InterPro:IPR005716 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay "142157_at, CG7014, RpS5b, S5b, RbS5b, RS5B_DROME" "IPR000235:Ribosomal protein S5/S7, IPR005716:Ribosomal protein S5/S7, eukaryotic/archaeal, IPR020606:Ribosomal protein S7, conserved site, IPR023798:Ribosomal protein S7 domain" CG7014 11-Aug-17 DroID_v2017_08 "Drer\zgc:153322, Drer\mrps7, Drer\rps5" "Scer\RSM7, Scer\RPS5" Cele\rps-5 "Xtro\rps5, Xtro\mrps7" "Mmus\Mrps7, Mmus\Rps5" "Hsap\MRPS7, Hsap\RPS5" "partially lethal - majority die,visible,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "mesothoracic tergum,ganglion mother cell" DRSC16173 I -1.921137249 0.535845581 0.376751955 0.192180571 -0.431933352 -0.83028135 FBgn0084007 CG41442 - http://flybase.org/reports/FBgn0084007 protein_coding_gene - - - CG41442 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002447 l(3)S7 lethal (3) S7 http://flybase.org/reports/FBgn0002447 - gene - - - l(3)S7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040989 CG5693 - http://flybase.org/reports/FBgn0040989 protein_coding_gene - - - CG5693 - CG5693 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001826 l(1)ts1 lethal (1) ts1 http://flybase.org/reports/FBgn0001826 - gene - - - l(1)ts1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,non-rescuable maternal effect,recessive,heat sensitive" "dorsal closure embryo,heat sensitive,embryonic/larval midgut" FBgn0266965 CR45416 - http://flybase.org/reports/FBgn0266965 non_protein_coding_gene - - - CR45416 - CR45416 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060733 l(3)S067206b lethal (3) S067206b http://flybase.org/reports/FBgn0060733 gene - - - "0672/06, l(3)S067206b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0046669 anon-38C.26 anon-38C.26 http://flybase.org/reports/FBgn0046669 gene - - - "38C.26, anon-38C.26" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016631 E(gl)2G Enhancer of glass 2G http://flybase.org/reports/FBgn0016631 - gene - - - E(gl)2G - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065571 l(2)SH0960 lethal (2) SH0960 http://flybase.org/reports/FBgn0065571 gene - - - "l(2)SH0960, l(2)SH2 0960" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013629 l(3)neo29 lethal (3) neo29 http://flybase.org/reports/FBgn0013629 - gene - - - l(3)neo29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026056 Rlip Ral interacting protein http://flybase.org/reports/FBgn0026056 - protein_coding_gene Ral GTPase binding ; GO:0017160 | inferred from physical interaction with Rala protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P16554 inferred from physical interaction with UniProtKB:P20439 protein binding ; GO:0005515 | inferred from physical interaction with Reps GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with HGNC:9841 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 regulation of Ras protein signal transduction ; GO:0046578 | inferred by curator from GO:0017160 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:9841 receptor-mediated endocytosis ; GO:0006898 | inferred from mutant phenotype" membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:9841 "D-RLIP, dRalBP, CG11622, RhoGAP-93B3, dRLIP, dRlip, Rlip, RLIP, DRLIP, RLIP1" "IPR000198:Rho GTPase-activating protein domain, IPR008936:Rho GTPase activation protein" CG11622 11-Aug-17 DroID_v2017_08 Drer\ralbp1 "Scer\RGD1, Scer\BEM3" Cele\rlbp-1 Xtro\ralbp1 "Mmus\Bcr, Mmus\Ralbp1" "Hsap\RALBP1, Hsap\BCR" "viable,fertile,visible" trichogen cell FBgn0262235 mir-983-1 mir-983-1 stem loop http://flybase.org/reports/FBgn0262235 miRNA_gene - - - "mir-983-1, miR-983-1, 983-1, CR42942, dme-mir-983-1, miR-983, dme-miR-983-1" - CR42942 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,lethal - all die before end of larval stage,some die during larval stage" "wing,wing vein" FBgn0035101 p130CAS p130CAS http://flybase.org/reports/FBgn0035101 protein_coding_gene - single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity axonal defasciculation ; GO:0007414 | inferred from mutant phenotype maintenance of cell polarity ; GO:0030011 | inferred from mutant phenotype focal adhesion ; GO:0005925 | inferred from sequence or structural similarity "CG1212, CT1293, p130CAS, Dcas, DCas, p130Cas" "IPR001452:SH3 domain, IPR014928:Serine rich protein interaction, IPR021901:CAS family, DUF3513" CG1212 11-Aug-17 DroID_v2017_08 "Drer\efs, Drer\nedd9, Drer\cass4, Drer\bcar1" - - "Xtro\bcar1, Xtro\cass4, Xtro\nedd9, Xtro\efs" "Mmus\Bcar1, Mmus\Nedd9, Mmus\Efs, Mmus\Cass4" "Hsap\CASS4, Hsap\NEDD9, Hsap\EFS, Hsap\BCAR1" "fertile,neuroanatomy defective,viable" "embryo,presumptive embryonic/larval central nervous system,intersegmental nerve,segmental nerve" FBgn0267313 CR45749 - http://flybase.org/reports/FBgn0267313 non_protein_coding_gene - - - CR45749 - CR45749 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264291 Det Deterin http://flybase.org/reports/FBgn0264291 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN000005165 cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from biological aspect of ancestor with PANTHER:PTN000799330 zinc ion binding ; GO:0008270 | inferred from sequence model spindle assembly ; GO:0051225 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with HGNC:593 inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype meiotic cytokinesis ; GO:0033206 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | traceable author statement regulation of signal transduction ; GO:0009966 | inferred from biological aspect of ancestor with PANTHER:PTN000005165 neurogenesis ; GO:0022008 | inferred from mutant phenotype meiotic chromosome segregation ; GO:0045132 | inferred from mutant phenotype inhibition of cysteine-type endopeptidase activity involved in apoptotic process ; GO:1990001 | inferred from biological aspect of ancestor with PANTHER:PTN000799330 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with NCBI_gi:6647543 mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype "meiotic spindle midzone ; GO:1990385 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000799330 mitotic spindle midzone ; GO:1990023 | colocalizes_with inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay chromosome passenger complex ; GO:0032133 | inferred from direct assay mitotic spindle midzone ; GO:1990023 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay" "svn, CG12265, scpo, Det, det" IPR001370:BIR repeat CG12265 11-Aug-17 DroID_v2017_08 "Drer\birc5b, Drer\birc5a, Drer\birc2, Drer\xiap, Drer\birc6" Scer\BIR1 "Cele\bir-1, Cele\bir-2, Cele\K11D12.9" "Xtro\birc5.2, Xtro\birc5.1, Xtro\birc2, Xtro\birc6, Xtro\birc7, Xtro\xiap" "Mmus\Birc3, Mmus\Naip2, Mmus\Naip5, Mmus\Naip6, Mmus\Naip1, Mmus\Xiap, Mmus\Birc5, Mmus\Birc7, Mmus\Birc6, Mmus\Birc2" "Hsap\BIRC6, Hsap\BIRC2, Hsap\BIRC5, Hsap\XIAP, Hsap\BIRC7, Hsap\BIRC8, Hsap\BIRC3, Hsap\NAIP" FBgn0267462 CR45812 - http://flybase.org/reports/FBgn0267462 non_protein_coding_gene - - - CR45812 - CR45812 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054025 CG34025 - http://flybase.org/reports/FBgn0054025 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "BP1082, HDC08169, CG34025" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001810:F-box domain" CG34025 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014256 l(2)DB4 lethal (2) DB4 http://flybase.org/reports/FBgn0014256 - gene - - - "DB4, l(2)DB4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023431 l(2)M65 lethal (2) M65 http://flybase.org/reports/FBgn0023431 - gene - - - l(2)M65 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,mating defective,male" FBgn0260451 CG14042 - http://flybase.org/reports/FBgn0260451 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14042, NEST:bs13e02, CG14041" - CG14042 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035124 ttm2 tiny tim 2 http://flybase.org/reports/FBgn0035124 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from biological aspect of ancestor with PANTHER:PTN000258719 ribonucleoprotein complex binding ; GO:0043021 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000258720 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrion organization ; GO:0007005 | inferred from sequence or structural similarity with ttm50 mitochondrial membrane organization ; GO:0007006 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000258720 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 nuclear speck ; GO:0016607 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with ttm50 "ttm2, CG12313, 20130405" "IPR004274:FCP1 homology domain, IPR027111:Mitochondrial import inner membrane translocase subunit Tim50, IPR023214:HAD-like domain" CG12313 11-Aug-17 DroID_v2017_08 Drer\timm50 Scer\TIM50 Cele\scpl-4 Xtro\timm50 Mmus\Timm50 Hsap\TIMM50 viable FBgn0083991 CG34155 - http://flybase.org/reports/FBgn0083991 protein_coding_gene - - - CG34155 - CG34155 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085524 CG40844 - http://flybase.org/reports/FBgn0085524 protein_coding_gene - - - CG40844 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267243 CR45683 - http://flybase.org/reports/FBgn0267243 non_protein_coding_gene - - - CR45683 - CR45683 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028625 l(2)01528 lethal (2) 01528 http://flybase.org/reports/FBgn0028625 gene - - - "l(2)38EFg, l(2)01528" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040476 Cyp12a2 Cytochrome P450-12a2 http://flybase.org/reports/FBgn0040476 gene - - - "CYP12A2, Cyp12a2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029922 CG14431 - http://flybase.org/reports/FBgn0029922 protein_coding_gene - - - CG14431 "IPR011989:Armadillo-like helical, IPR032675:Leucine-rich repeat domain, L domain-like" CG14431 11-Aug-17 DroID_v2017_08 - - Cele\cdh-5 Xtro\trhd Mmus\Mypop "Hsap\PCDHB1, Hsap\MYPOP" viable FBgn0015772 Nak Numb-associated kinase http://flybase.org/reports/FBgn0015772 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with UniProt:P40494 inferred from sequence or structural similarity with UniProtKB:P38080 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000539981 protein binding ; GO:0005515 | inferred from physical interaction with numb protein kinase activity ; GO:0004672 | non-traceable author statement AP-2 adaptor complex binding ; GO:0035612 | inferred from direct assay PTB domain binding ; GO:0051425 | inferred from physical interaction with numb asymmetric cell division ; GO:0008356 | inferred from mutant phenotype inferred from physical interaction with numb regulation of clathrin-dependent endocytosis ; GO:2000369 | inferred from genetic interaction with Chc inferred from genetic interaction with AP-2α dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProt:P40494 inferred from sequence or structural similarity with UniProtKB:P38080 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000539981 positive regulation of Notch signaling pathway ; GO:0045747 | inferred from biological aspect of ancestor with PANTHER:PTN001121691 axon ; GO:0030424 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000539982 "CG10637, nak, Nak" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain" CG10637 11-Aug-17 DroID_v2017_08 "Drer\bmp2k, Drer\gak, Drer\aak1a, Drer\aak1b" "Scer\ARK1, Scer\PRK1, Scer\AKL1" "Cele\sel-5, Cele\tag-257" "Xtro\aak1, Xtro\gak, Xtro\bmp2k" "Mmus\Aak1, Mmus\Bmp2k, Mmus\Gak" "Hsap\AAK1, Hsap\GAK, Hsap\BMP2K" " embryonic stage | 0-12hr , embryonic stage -- adult stage , embryonic stage "

ubiquitous "viable,fertile,neuroanatomy defective,recessive,visible" "dendritic arborizing neuron,dendrite | larval stage,dorsal multidendritic neuron ddaC,somatic clone,dendrite | larval stage | somatic clone,dendritic arborizing neuron | larval stage,dendrite | larval stage109(2)80,scolopidial neuron | embryonic stage,wing sensillum,head sensillum,adult mesothoracic sensillum,embryonic/larval salivary gland,dendrite | larval stage | somatic clone477,dendritic spine | larval stage, with Df(2L)TW3, ,dorsal multidendritic neuron ddaA | larval stage,dendrite | larval stage, with Df(2L)TW3, ,dorsal multidendritic neuron ddaE | larval stage,dendrite | larval stageIG1-1" FBgn0085500 CR40601 - http://flybase.org/reports/FBgn0085500 pseudogene_attribute - - - "CG40601, CR40601, CG12717-related" - CR40601 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044412 Scim15 Sensitized chromosome inheritance modifier 15 http://flybase.org/reports/FBgn0044412 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0263342 CR43423 - http://flybase.org/reports/FBgn0263342 non_protein_coding_gene - - - CR43423 - CR43423 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032517 CG7099 - http://flybase.org/reports/FBgn0032517 protein_coding_gene "RNA polymerase III type 2 promoter sequence-specific DNA binding ; GO:0001003 | inferred from biological aspect of ancestor with PANTHER:PTN001032354 transcription factor activity, core RNA polymerase III binding ; GO:0000995 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001032354 transcription factor activity, RNA polymerase III transcription factor binding ; GO:0001007 | inferred from biological aspect of ancestor with PANTHER:PTN001032354 RNA polymerase III type 1 promoter sequence-specific DNA binding ; GO:0001002 | inferred from biological aspect of ancestor with PANTHER:PTN001032354" transcription initiation from RNA polymerase III promoter ; GO:0006384 | inferred from biological aspect of ancestor with PANTHER:PTN001032354 5S class rRNA transcription from RNA polymerase III type 1 promoter ; GO:0042791 | inferred from biological aspect of ancestor with PANTHER:PTN001032354 tRNA transcription ; GO:0009304 | inferred from biological aspect of ancestor with PANTHER:PTN001032354 transcription factor TFIIIC complex ; GO:0000127 | inferred from biological aspect of ancestor with PANTHER:PTN001032354 "CG7099, FBgn 32517, dTFIIIC220" IPR007309:B-block binding subunit of TFIIIC CG7099 11-Aug-17 DroID_v2017_08 Drer\gtf3c1 Scer\TFC3 "Cele\CE7X_3.1, Cele\tftc-1" - Mmus\Gtf3c1 Hsap\GTF3C1 "viable,visible" trichogen cell FBgn0263559 mir-2535b mir-2535b stem loop http://flybase.org/reports/FBgn0263559 miRNA_gene - - - "mir-2535b, dme-mir-2535b, CR43544" - CR43544 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017401 eve::ftz eve::ftz http://flybase.org/reports/FBgn0017401 - engineered_fusion_gene - - - eve::ftz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263477 scaRNA:PsiU1-6 small Cajal body-specific RNA : PsiU1-6 http://flybase.org/reports/FBgn0263477 snoRNA_gene snRNA pseudouridylation guide activity ; GO:0030565 | inferred from direct assay rRNA pseudouridylation guide activity ; GO:0030559 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "snoRNA:dmt-a, scaRNA:PsiU1-6, pugU1-6" - CR43592 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022396 HelII Helicase II http://flybase.org/reports/FBgn0022396 - gene ATP-dependent helicase activity ; GO:0008026 | inferred from direct assay DNA duplex unwinding ; GO:0032508 | inferred from direct assay - "dhel II, HelII" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036735 Edc3 Enhancer of decapping 3 http://flybase.org/reports/FBgn0036735 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P23128 inferred from physical interaction with UniProtKB:Q5U127 inferred from physical interaction with UniProtKB:Q9W1H5 mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000341086 cytoplasmic mRNA processing body assembly ; GO:0033962 | inferred from biological aspect of ancestor with PANTHER:PTN000341086 mRNA catabolic process ; GO:0006402 | inferred from mutant phenotype deadenylation-independent decapping of nuclear-transcribed mRNA ; GO:0031087 | inferred from biological aspect of ancestor with PANTHER:PTN000341086 cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "Edc3, DmEDC3, CG6311, EDC3, LSM16, LSm16" "IPR025762:DFDF domain, IPR004443:YjeF N-terminal domain, IPR034107:Lsm16, N-terminal, IPR025609:Lsm14-like, N-terminal, IPR019050:FDF domain" CG6311 11-Aug-17 DroID_v2017_08 "Drer\apoa1bp, Drer\edc3, Drer\yjefn3" "Scer\EDC3, Scer\YNL200C" Cele\edc-3 "Xtro\edc3, Xtro\apoa1bp" "Mmus\Apoa1bp, Mmus\Edc3" "Hsap\YJEFN3, Hsap\EDC3, Hsap\NAXE" viable FBgn0011848 tRNA:Glu-TTC-1-6 transfer RNA:Glutamic acid-TTC 1-6 http://flybase.org/reports/FBgn0011848 "FBgn0003771, FBgn0011846, FBgn0050453, FBgn0060241" tRNA_gene GAA codon-amino acid adaptor activity ; GO:0033459 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033459 cytosol ; GO:0005829 | inferred by curator from GO:0033459 "CR30453, glu-tRNA-4, AE002787.trna4-GluTTC, tRNA:E4, tRNA:E:TTC:AE002787-a, tRNA:glu4:56Fa, tRNA:Glu, chr2R.trna62-GluTTC, tRNA:Glu-TTC-1-6, tRNA:E4:56Fa, tRNA-Glu-TTC-1-6, GAA" - CR30453 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267790 rump rumpelstiltskin http://flybase.org/reports/FBgn0267790 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA 3'-UTR binding ; GO:0003730 | traceable author statement mRNA binding ; GO:0003729 | inferred from direct assay mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay "pole plasm oskar mRNA localization ; GO:0045451 | inferred from genetic interaction with lost pole cell development ; GO:0007277 | inferred from genetic interaction with lost mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from genetic interaction with nos anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype anterior/posterior pattern specification ; GO:0009952 | inferred from genetic interaction with lost" nuclear chromatin ; GO:0000790 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay omega speckle ; GO:0035062 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "hrp59, S5, p70, HnRNP-S5, CG9373, hnRNP M, rump, p75, cg9373, Hrp59" IPR000504:RNA recognition motif domain CG9373 11-Aug-17 DroID_v2017_08 "Drer\hnrnpm, Drer\myef2" "Scer\HRB1, Scer\GBP2" Cele\C25A1.4 "Xtro\hnrnpm, Xtro\myef2" "Mmus\Hnrnpm, Mmus\Myef2" "Hsap\MYEF2, Hsap\HNRNPM, Hsap\SART3" DRSC16480 K -1.123479427 -0.435853837 -0.892071498 -0.271251098 1.733494599 0.171233244 FBgn0086046 snoRNA:Me28S-A1705 - http://flybase.org/reports/FBgn0086046 snoRNA_gene - - - "snoRNA:Me28S-A1705, Me28S-Am1705, CR34675" - CR34675 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011414 l(3)j9A5 lethal (3) j9A5 http://flybase.org/reports/FBgn0011414 - gene - - - l(3)j9A5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043477 l(3)66EFi lethal (3) 66EFi http://flybase.org/reports/FBgn0043477 gene - - - l(3)66EFi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267025 CR45469 - http://flybase.org/reports/FBgn0267025 non_protein_coding_gene - - - CR45469 - CR45469 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005226 l(3)R12 lethal (3) R12 http://flybase.org/reports/FBgn0005226 - gene - - - l(3)R12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039770 CG15537 - http://flybase.org/reports/FBgn0039770 protein_coding_gene corticotropin-releasing hormone binding ; GO:0051424 | inferred from electronic annotation with InterPro:IPR008435 hormone binding ; GO:0042562 | inferred from sequence or structural similarity with MGI:MGI:88497 hormone metabolic process ; GO:0042445 | inferred from sequence or structural similarity with MGI:MGI:88497 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with RGD:2403 CG15537 IPR008435:Corticotropin-releasing factor-binding protein CG15537 11-Aug-17 DroID_v2017_08 Drer\crhbp - - Xtro\crhbp Mmus\Crhbp Hsap\CRHBP FBgn0261649 tinc tincar http://flybase.org/reports/FBgn0261649 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of eye photoreceptor cell development ; GO:0042478 | inferred from mutant phenotype - "tinc, CG31247, CG7723, CG14320, CG14319, CG31246" - CG31247 11-Aug-17 DroID_v2017_08 - - "Cele\spp-14, Cele\T11F9.12, Cele\spp-23, Cele\spp-5, Cele\spp-17, Cele\spp-3, Cele\spp-21, Cele\spp-9, Cele\spp-2, Cele\K09F5.6, Cele\spp-6, Cele\spp-4" - - - DRSC22723 I -0.757444431 -1.959206401 -0.603882794 -0.655462853 0.975836265 0.628206552 FBgn0027159 l(2)PN-11 lethal (2) PN-11 http://flybase.org/reports/FBgn0027159 - gene - - - l(2)PN-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033985 CG10257 - http://flybase.org/reports/FBgn0033985 protein_coding_gene - negative regulation of apoptotic process ; GO:0043066 | inferred from electronic annotation with InterPro:IPR010695 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - "BcDNA:RH51312, CG10257" IPR010695:Fas apoptotic inhibitory molecule 1 CG10257 11-Aug-17 DroID_v2017_08 "Drer\faimb, Drer\faima" - Cele\C44B11.1 Xtro\faim "Mmus\Faiml, Mmus\Faim" Hsap\FAIM viable FBgn0025762 l(3)89En lethal (3) 89En http://flybase.org/reports/FBgn0025762 - gene - - - "l(3)M2511, l(3)89En" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016706 Reg-11 Rhythmically expressed gene 11 http://flybase.org/reports/FBgn0016706 - gene - - - "Dreg-11, Reg-11" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | late , adult stage " adult head

FBgn0022378 Pt-12 Larval protein-12 http://flybase.org/reports/FBgn0022378 - gene - - - Pt-12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035528 CG15012 - http://flybase.org/reports/FBgn0035528 protein_coding_gene - - - CG15012 IPR007919:Uncharacterised protein family UPF0220 CG15012 11-Aug-17 DroID_v2017_08 Drer\tmem50a Scer\VPS68 Cele\Y74C10AL.2 "Xtro\tmem50b, Xtro\tmem50a" "Mmus\Tmem50a, Mmus\Tmem50b" "Hsap\TMEM50A, Hsap\TMEM50B" "viable,fertile" FBgn0038467 AdSL Adenylosuccinate Lyase http://flybase.org/reports/FBgn0038467 protein_coding_gene "(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity ; GO:0070626 | inferred from biological aspect of ancestor with PANTHER:PTN000154581 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity ; GO:0004018 | inferred from sequence or structural similarity with RGD:1307617 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity ; GO:0004018 | inferred from biological aspect of ancestor with PANTHER:PTN000154581" purine nucleotide metabolic process ; GO:0006163 | inferred from sequence or structural similarity with RGD:1307617 'de novo' AMP biosynthetic process ; GO:0044208 | inferred from biological aspect of ancestor with PANTHER:PTN000154581 cytosol ; GO:0005829 | inferred from sequence or structural similarity with RGD:1307617 "CG3590, AdSL" "IPR000362:Fumarate lyase family, IPR004769:Adenylosuccinate lyase, IPR008948:L-Aspartase-like, IPR024083:Fumarase/histidase, N-terminal, IPR020557:Fumarate lyase, conserved site, IPR019468:Adenylosuccinate lyase C-terminal, IPR022761:Fumarate lyase, N-terminal" CG3590 11-Aug-17 DroID_v2017_08 Drer\adsl Scer\ADE13 Cele\adsl-1 Xtro\adsl Mmus\Adsl Hsap\ADSL "lethal - all die during larval stage,recessive,long lived,viable" FBgn0010186 tu(3)mt tu(3)mt http://flybase.org/reports/FBgn0010186 - gene - - - "mt, tu(3)mt" - - 11-Aug-17 DroID_v2017_08 - - - - - - melanotic mass phenotype FBgn0051466 CG31466 - http://flybase.org/reports/FBgn0051466 protein_coding_gene - - - CG31466 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053379 5SrRNA:CR33379 5SrRNA:CR33379 http://flybase.org/reports/FBgn0053379 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33379, 5SrRNA:CR33379" - CR33379 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267475 CR45825 - http://flybase.org/reports/FBgn0267475 non_protein_coding_gene - - - CR45825 - CR45825 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038481 CG17475 - http://flybase.org/reports/FBgn0038481 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP131, CG17475" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG17475 11-Aug-17 DroID_v2017_08 - - Cele\nhl-3 - Mmus\Prtn3 "Hsap\PRTN3, Hsap\AZU1" viable FBgn0267758 CR46089 - http://flybase.org/reports/FBgn0267758 non_protein_coding_gene - - - CR46089 - CR46089 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039566 CG4849 - http://flybase.org/reports/FBgn0039566 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR005225, InterPro:IPR005517 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity" "translational elongation ; GO:0006414 | inferred from sequence or structural similarity positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D" precatalytic spliceosome ; GO:0071011 | inferred from direct assay U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity with SGD:S000001656 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from physical interaction with Prp8 cytosol ; GO:0005829 | inferred from sequence or structural similarity small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000001656 cytoplasm ; GO:0005737 | inferred from direct assay "Snu114, CG4849, eftud2, eEF2, EFTUD2" "IPR000640:Translation elongation factor EFG, V domain, IPR000795:Transcription factor, GTP-binding domain, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR005225:Small GTP-binding protein domain, IPR005517:Translation elongation factor EFG/EF2, domain IV, IPR009000:Translation protein, beta-barrel domain, IPR009022:Elongation factor G, III-V domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR031950:116 kDa U5 small nuclear ribonucleoprotein component, N-terminal" CG4849 11-Aug-17 DroID_v2017_08 "Drer\eftud2, Drer\eef2l2, Drer\eef2b, Drer\eef2a.1, Drer\eef2a.2" "Scer\EFT2, Scer\SNU114, Scer\EFT1" Cele\eftu-2 "Xtro\eef2.2, Xtro\eftud2, Xtro\eef2.1" "Mmus\Eef2, Mmus\Eftud2" "Hsap\EEF2, Hsap\EFTUD2" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC27175 EK 0.257350051 -0.020714416 -2.861726768 0.631922756 -2.421490211 -1.551048014 FBgn0060935 l(3)S041316a lethal (3) S041316a http://flybase.org/reports/FBgn0060935 gene - - - "0413/16, l(3)S041316a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0259355 EP-J59 - http://flybase.org/reports/FBgn0259355 gene - - - EP-J59 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin,chaeta" FBgn0010061 M(2)34b M(2)34b http://flybase.org/reports/FBgn0010061 - gene - - - M(2)34b - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013749 Arf102F ADP ribosylation factor at 102F http://flybase.org/reports/FBgn0013749 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006689, InterPro:IPR024156 NAD(P)+-protein-arginine ADP-ribosyltransferase activity ; GO:0003956 | inferred from direct assay" small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 compound eye development ; GO:0048749 | inferred from mutant phenotype protein ADP-ribosylation ; GO:0006471 | inferred from direct assay synaptic vesicle endocytosis ; GO:0048488 | traceable author statement neurotransmitter secretion ; GO:0007269 | traceable author statement endosomal transport ; GO:0016197 | traceable author statement intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR024156 cellular_component ; GO:0005575 | no biological data available "CG11027, dARFII, ARFII, ARF2, Arf102F, Arf102E, P40945, Arf5, arf102F, Arf4, Arf2, arf4" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR024156:Small GTPase superfamily, ARF type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG11027 11-Aug-17 DroID_v2017_08 "Drer\arl14, Drer\arl6, Drer\arl5a, Drer\arf2a, Drer\arf3b, Drer\arl4ca, Drer\arl4d, Drer\arl4cb, Drer\arl8, Drer\arf4a, Drer\si:ch1073-165f9.2, Drer\arl4ab, Drer\zgc:77650, Drer\arf4b, Drer\zgc:110286, Drer\arf2b, Drer\arf5, Drer\arl11, Drer\trim23, Drer\arf1, Drer\arl5c, Drer\arf3a, Drer\arl4aa, Drer\arl9" "Scer\ARF1, Scer\ARF2" "Cele\arf-3, Cele\arf-1.2" "Xtro\arf3, Xtro\arf4, Xtro\arl9, Xtro\arl11, Xtro\arl5b, Xtro\arl11, Xtro\arl6, Xtro\arf5, Xtro\arl4a, Xtro\arl14, Xtro\arl5c, Xtro\trim23, Xtro\arl4c, Xtro\arl5a, Xtro\arf1" "Mmus\Arl4c, Mmus\Arl5a, Mmus\Trim23, Mmus\Arl9, Mmus\Arl5c, Mmus\Arl4d, Mmus\Arf4, Mmus\Arf5, Mmus\Arf3, Mmus\Arl4a, Mmus\Arl11, Mmus\Arf2, Mmus\Arl6, Mmus\Arl5b, Mmus\Arf1" "Hsap\ARF4, Hsap\ARL4A, Hsap\ARF1, Hsap\ARL6, Hsap\ARL5C, Hsap\ARL14, Hsap\ARF3, Hsap\ARL5B, Hsap\ARL11, Hsap\ARL4D, Hsap\ARL9, Hsap\ARL5A, Hsap\ARL4C, Hsap\TRIM23, Hsap\ARF5, Hsap\ARL17B" adult stage lethal eye DRSC17195 E 0.018030843 -0.366383828 -0.531037611 -2.163472001 0.535574887 1.141903728 FBgn0030720 CG8939 - http://flybase.org/reports/FBgn0030720 protein_coding_gene rRNA methyltransferase activity ; GO:0008649 | inferred from electronic annotation with InterPro:IPR028589 rRNA methylation ; GO:0031167 | inferred from electronic annotation with InterPro:IPR028589 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012920 "CG8939, dSpb1" "IPR002877:Ribosomal RNA methyltransferase FtsJ domain, IPR012920:Ribosomal RNA methyltransferase, Spb1, C-terminal, IPR015507:Ribosomal RNA large subunit methyltransferase E, IPR024576:Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381, IPR028589:AdoMet-dependent rRNA methyltransferase, Spb1, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG8939 11-Aug-17 DroID_v2017_08 "Drer\ftsj3, Drer\ftsj2" "Scer\SPB1, Scer\MRM2" Cele\H06I04.3 Xtro\ftsj3 "Mmus\Ftsj3, Mmus\Mrm2" "Hsap\MRM2, Hsap\FTSJ3" viable FBgn0082344 HM505 HM505 http://flybase.org/reports/FBgn0082344 gene - - - HM505 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030018 slpr slipper http://flybase.org/reports/FBgn0030018 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 JUN kinase kinase kinase activity ; GO:0004706 | inferred from direct assay protein kinase activity ; GO:0004672 | non-traceable author statement protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with UniProtKB:Q16584 JUN kinase kinase kinase activity ; GO:0004706 | inferred from sequence or structural similarity with HGNC:6849 inferred from sequence or structural similarity with HGNC:6850 protein kinase activity ; GO:0004672 | inferred from direct assay "positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype activation of JUN kinase activity ; GO:0007257 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement response to heat ; GO:0009408 | inferred from mutant phenotype imaginal disc-derived female genitalia morphogenesis ; GO:0048804 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from genetic interaction with Jra inferred from genetic interaction with Rac1 inferred from genetic interaction with puc dorsal closure, elongation of leading edge cells ; GO:0007394 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay protein autophosphorylation ; GO:0046777 | inferred from sequence or structural similarity with UniProtKB:Q16584 dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype activation of JUN kinase activity ; GO:0007257 | inferred from mutant phenotype activation of JNKK activity ; GO:0007256 | traceable author statement cellular response to ethanol ; GO:0071361 | inferred from mutant phenotype" cell cortex ; GO:0005938 | inferred from direct assay "dMLK, MLK2, Mlk2, dMLK2, CG2272, slpr, Slpr, MLK, JNKKK, D-MLK, Mlk" "IPR000719:Protein kinase domain, IPR001452:SH3 domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG2272 11-Aug-17 DroID_v2017_08 "Drer\dstyk, Drer\LOC405768, Drer\ripk3, Drer\zak, Drer\map3k9, Drer\ripk2, Drer\si:ch211-120p12.3, Drer\map3k10, Drer\mos, Drer\ripk4, Drer\lrrk2, Drer\pbk, Drer\ripk1l" - "Cele\mlk-1, Cele\ark-1" "Xtro\LOC100490493, Xtro\ankk1, Xtro\map3k7, Xtro\map3k9, Xtro\ripk1, Xtro\pbk, Xtro\mlkl, Xtro\lrrk2, Xtro\zak, Xtro\ripk4, Xtro\map3k10, Xtro\dstyk, Xtro\lrrk1" "Mmus\Map3k10, Mmus\Pbk, Mmus\Mlkl, Mmus\Ripk3, Mmus\Map3k11, Mmus\Lrrk1, Mmus\Ripk4, Mmus\Ripk2, Mmus\Mos, Mmus\Zak, Mmus\Map3k7, Mmus\Lrrk2, Mmus\Map3k9, Mmus\Dstyk, Mmus\BC021891, Mmus\Ripk1" "Hsap\MLKL, Hsap\LRRK1, Hsap\MAP3K9, Hsap\MAP3K20, Hsap\RIPK3, Hsap\MAP3K11, Hsap\MAP3K10, Hsap\DSTYK, Hsap\RIPK1, Hsap\PBK, Hsap\MAP3K7, Hsap\RIPK4, Hsap\MOS, Hsap\LRRK2, Hsap\RIPK2, Hsap\MAP3K21, Hsap\EGFR" " embryonic stage , adult stage , embryonic stage | early , embryonic stage&&adult stage " "

ubiquitous , head && thorax

, organism

" "visible,heat stress response defective,male,female,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal,recessive,rescuable maternal effect,partially,lethal - all die during embryonic stage,long lived,partially lethal - majority live,short lived,partially lethal - majority die,some die during pupal stage" "scutellum,scutellar bristle,embryonic/first instar larval cuticle,dorsal,adult thorax,mesothoracic tergum,embryonic dorsal epidermis,maxillary palpus,female terminalia,adult external thorax,dorsal closure embryo,rescuable maternal effect,embryonic leading edge cell,dorsal appendage,maternal effect,somatic clone,dorsal ectoderm,wing,male terminalia,adult abdominal segment" FBgn0263455 CR43478 - http://flybase.org/reports/FBgn0263455 non_protein_coding_gene - - - CR43478 - CR43478 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034786 CG13531 - http://flybase.org/reports/FBgn0034786 protein_coding_gene molecular_function ; GO:0003674 | no biological data available axon extension ; GO:0048675 | inferred from sequence or structural similarity with MGI:MGI:2444989 axon ; GO:0030424 | inferred from sequence or structural similarity with MGI:MGI:2444989 CG13531 "IPR011990:Tetratricopeptide-like helical domain, IPR028103:Spatacsin, IPR028107:Spatacsin, C-terminal domain" CG13531 11-Aug-17 DroID_v2017_08 "Drer\efemp2b, Drer\spg11" - - - Mmus\Spg11 Hsap\SPG11 "viable,fertile" FBgn0053398 5SrRNA:CR33398 5SrRNA:CR33398 http://flybase.org/reports/FBgn0053398 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33398, 5SrRNA:CR33398" - CR33398 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015787 Ppi-16 Protein phosphatase 1 Interacting protein clone-16 http://flybase.org/reports/FBgn0015787 - gene - - - Ppi-16 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053439 5SrRNA:CR33439 5SrRNA:CR33439 http://flybase.org/reports/FBgn0053439 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33439, 5SrRNA:CR33439" - CR33439 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262434 mir-11 mir-11 stem loop http://flybase.org/reports/FBgn0262434 miRNA_gene - negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with E2f1 cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype negative regulation of cell death ; GO:0060548 | inferred from genetic interaction with E2f1 - "miR-11, mir-11, dme-mir-11, Dme-miR-11, 11, CR42992, CR32929, MiR-11, dme-miR-11" - CR42992 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0033873 CG6337 - http://flybase.org/reports/FBgn0033873 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 CG6337 "IPR000668:Peptidase C1A, papain C-terminal, IPR013128:Peptidase C1A, IPR013201:Cathepsin propeptide inhibitor domain (I29)" CG6337 11-Aug-17 DroID_v2017_08 "Drer\ctsk, Drer\ctsz, Drer\ctsh, Drer\ctsla, Drer\si:dkey-239j18.2, Drer\ctsf, Drer\wu:fa26c03, Drer\ctsbb, Drer\si:dkey-183k8.2, Drer\si:dkey-267n13.1, Drer\ctsba, Drer\si:dkey-239j18.3, Drer\si:dkey-269i1.4, Drer\cts12, Drer\ctss2.2, Drer\LOC100536033, Drer\MGC174155, Drer\zgc:103438, Drer\LOC100333521, Drer\ctss1, Drer\ctslb, Drer\ctsc, Drer\zgc:174855, Drer\ctsl.1, Drer\si:dkey-228a15.1, Drer\zgc:174153, Drer\ctsll, Drer\ctss2.1, Drer\zgc:110239" - "Cele\Y113G7B.15, Cele\Y51A2D.8, Cele\Y40H7A.10, Cele\tag-329, Cele\Y51A2D.1, Cele\F15D4.4" "Xtro\ctsh, Xtro\LOC100490139, Xtro\ctsl, Xtro\LOC100498238, Xtro\ctsc, Xtro\ctsb, Xtro\ctss, Xtro\ctsz, Xtro\ctsv" "Mmus\Ctsh, Mmus\Ctsk, Mmus\Ctsl, Mmus\Ctss, Mmus\Ctsq, Mmus\Ctla2a, Mmus\Cts3, Mmus\Cts8, Mmus\Cts7, Mmus\Ctsj, Mmus\Cts6, Mmus\Ctsc, Mmus\BC051665, Mmus\Ctsll3, Mmus\Ctsb, Mmus\4930486L24Rik, Mmus\Ctsf, Mmus\Ctso, Mmus\Ctsw, Mmus\Ctsr, Mmus\Ctla2b, Mmus\Ctsz, Mmus\Ctsm" "Hsap\CTSW, Hsap\CTSL, Hsap\CTSF, Hsap\CTSS, Hsap\CTSH, Hsap\CTSK, Hsap\CTSV, Hsap\CTSB, Hsap\CTSC, Hsap\CTSZ" viable FBgn0010022 E(Dl)D165 Enhancer of Delta D165 http://flybase.org/reports/FBgn0010022 - gene - - - E(Dl)D165 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038800 CG15921 - http://flybase.org/reports/FBgn0038800 protein_coding_gene - - - CG15921 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021996 l(2)k09501 lethal (2) k09501 http://flybase.org/reports/FBgn0021996 - gene - - - l(2)k09501 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031785 CG13991 - http://flybase.org/reports/FBgn0031785 protein_coding_gene - - - CG13991 - CG13991 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003563 Su(Gl)27 Suppressor of Glued 27 http://flybase.org/reports/FBgn0003563 - gene - - - "Su(Gl), Su(Gl)27" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259275 GS-C31 - http://flybase.org/reports/FBgn0259275 gene - - - "GS-C31, C31" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0041615 SM3-8 SM3-8 http://flybase.org/reports/FBgn0041615 gene - - - SM3-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033851 CG13332 - http://flybase.org/reports/FBgn0033851 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13332 - CG13332 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0067059 P316 P316 http://flybase.org/reports/FBgn0067059 gene - - - P316 - - 11-Aug-17 DroID_v2017_08 - - - - - - neurophysiology defective FBgn0039755 CG15531 - http://flybase.org/reports/FBgn0039755 protein_coding_gene "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water ; GO:0016717 | inferred from electronic annotation with InterPro:IPR015876" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015876 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804 - CG15531 "IPR005804:Fatty acid desaturase domain, IPR015876:Acyl-CoA desaturase" CG15531 11-Aug-17 DroID_v2017_08 "Drer\scdb, Drer\scd" Scer\OLE1 "Cele\fat-6, Cele\fat-7, Cele\fat-5" Xtro\scd "Mmus\Scd4, Mmus\Scd2, Mmus\Scd1, Mmus\Scd3" "Hsap\SCD5, Hsap\SCD" viable FBgn0262021 CG42832 - http://flybase.org/reports/FBgn0262021 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42832 - CG42832 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259668 B2038 - http://flybase.org/reports/FBgn0259668 gene - - - B2038 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "1st posterior cell,wing,wing sensillum,ectopic,wing vein,chaeta" FBgn0032166 CG4619 - http://flybase.org/reports/FBgn0032166 protein_coding_gene - - - "CG31879, CG4619" - CG4619 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032223 GATAd GATAd http://flybase.org/reports/FBgn0032223 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR012934, InterPro:IPR013088 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001228 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with MGI:MGI:107516 RNA polymerase II transcription factor binding ; GO:0001085 | inferred from biological aspect of ancestor with PANTHER:PTN000801139" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088 cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000801139" nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 "dGATAd, dGATA-D, CG5034, GATAd" "IPR000679:Zinc finger, GATA-type, IPR012934:Zinc finger, AD-type" CG5034 11-Aug-17 DroID_v2017_08 "Drer\gata3, Drer\gata5, Drer\gata2b, Drer\gata2a, Drer\gata1b, Drer\zglp1, Drer\gata6, Drer\gata1a, Drer\trps1, Drer\gata4" "Scer\GAT4, Scer\GLN3, Scer\SRD1, Scer\GAT3, Scer\GAT2, Scer\GAT1, Scer\GZF3, Scer\ECM23, Scer\DAL80" "Cele\elt-4, Cele\end-1, Cele\egl-18, Cele\elt-6, Cele\elt-3, Cele\elt-1, Cele\med-1, Cele\med-2, Cele\elt-2, Cele\end-3, Cele\elt-7" "Xtro\gata6, Xtro\trps1, Xtro\gata2, Xtro\gata3, Xtro\gata1, Xtro\gata5, Xtro\gata4" "Mmus\Gata3, Mmus\Trps1, Mmus\Gata5, Mmus\Zglp1, Mmus\Gata4, Mmus\Gata1, Mmus\Gata6, Mmus\Gata2" "Hsap\GATA6, Hsap\TRPS1, Hsap\GATA5, Hsap\GATA2, Hsap\GATA4, Hsap\GATA1, Hsap\ZGLP1, Hsap\GATA3" FBgn0052457 CG32457 - http://flybase.org/reports/FBgn0052457 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32457 - CG32457 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0034578 CG15653 - http://flybase.org/reports/FBgn0034578 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 structural constituent of ribosome ; GO:0003735 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 cytosolic large ribosomal subunit ; GO:0022625 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 CG15653 IPR014807:Cytochrome oxidase assembly protein 1 CG15653 11-Aug-17 DroID_v2017_08 "Drer\rpl37, Drer\coa1" "Scer\RPL37A, Scer\RPL37B" "Cele\Y38C1AA.14, Cele\T23F2.2" Xtro\coa1 - Hsap\COA1 viable FBgn0016837 l(1)MZ5 lethal (1) MZ5 http://flybase.org/reports/FBgn0016837 - gene - - - "l(1)MZ5, M5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038185 CG14363 - http://flybase.org/reports/FBgn0038185 protein_coding_gene - - - CG14363 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC25183 K -0.597533226 0.144497612 0.798615875 -0.00056561 1.661396032 1.017633884 FBgn0022166 l(2)45Bc lethal (2) 45Bc http://flybase.org/reports/FBgn0022166 FBgn0015479 gene - - - "l(2)k05611b, l(2)k05611a, l(2)k05611, l(2)45Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0034928 CG13562 - http://flybase.org/reports/FBgn0034928 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 - - CG13562 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG13562 11-Aug-17 DroID_v2017_08 - - - - - Hsap\PNLIP FBgn0010838 l(3)04281 lethal (3) 04281 http://flybase.org/reports/FBgn0010838 - gene - - - l(3)04281 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0085206 CG34177 - http://flybase.org/reports/FBgn0085206 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model "CG34177, CG12677" IPR029277:Single domain Von Willebrand factor type C domain CG34177 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082674 Fas1::kirre Fas1::kirre http://flybase.org/reports/FBgn0082674 engineered_fusion_gene - - - Fas1::kirre - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053810 His1:CG33810 His1:CG33810 http://flybase.org/reports/FBgn0053810 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33810, His1:CG33810" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33810 11-Aug-17 DroID_v2017_08 "Drer\h1fx, Drer\si:ch73-36p18.1, Drer\si:dkey-108k21.21, Drer\zgc:163061, Drer\si:ch211-113a14.24, Drer\h1m, Drer\zgc:153405, Drer\si:dkey-261m9.12, Drer\zgc:110425, Drer\si:dkey-108k21.14, Drer\si:ch1073-159d7.7, Drer\h1f0, Drer\histh1l, Drer\si:dkey-108k21.10, Drer\zgc:110216" Scer\HHO1 "Cele\his-24, Cele\hil-4, Cele\hil-5, Cele\hil-3, Cele\hil-6, Cele\hil-2, Cele\hil-1" - "Mmus\Hist1h1t, Mmus\H1fnt, Mmus\Hils1, Mmus\Hist1h1b, Mmus\Hist1h1c, Mmus\Hist1h1e, Mmus\Hist1h1d, Mmus\H1foo, Mmus\Hist1h1a, Mmus\H1fx" "Hsap\HIST1H1T, Hsap\H1F0, Hsap\HIST1H1B, Hsap\HIST1H1D, Hsap\H1FOO, Hsap\HIST1H1E, Hsap\H1FX, Hsap\HIST1H1A, Hsap\HIST1H1C, Hsap\H1FNT" FBgn0022052 l(2)k08201 lethal (2) k08201 http://flybase.org/reports/FBgn0022052 - gene - - - l(2)k08201 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036301 CG4069 - http://flybase.org/reports/FBgn0036301 protein_coding_gene - - - "anon-WO0172774.58, CG4069" "IPR015915:Kelch-type beta propeller, IPR015916:Galactose oxidase, beta-propeller, IPR011498:Kelch repeat type 2" CG4069 11-Aug-17 DroID_v2017_08 "Drer\hcfc1a, Drer\rabepk, Drer\hcfc1b, Drer\klhdc4" "Scer\KEL2, Scer\KEL1, Scer\KEL3" "Cele\Y50D7A.1, Cele\F53E4.1, Cele\hcf-1" Xtro\klhdc4 "Mmus\Hcfc1, Mmus\Fbxo42, Mmus\Hcfc2, Mmus\Klhdc4, Mmus\Klhdc3, Mmus\Rabepk, Mmus\Lztr1" "Hsap\HCFC1, Hsap\LOC105371397, Hsap\RABEPK, Hsap\HCFC2, Hsap\FBXO42, Hsap\KLHDC3, Hsap\LZTR1, Hsap\KLHDC4" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0023395 Chd3 Chd3 http://flybase.org/reports/FBgn0023395 - protein_coding_gene "ATP-dependent helicase activity ; GO:0008026 | inferred from electronic annotation with InterPro:IPR002464 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR002464 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 DNA binding ; GO:0003677 | inferred from direct assay helicase activity ; GO:0004386 | inferred from sequence or structural similarity nucleosome-dependent ATPase activity ; GO:0070615 | inferred from direct assay nucleosome binding ; GO:0031491 | inferred from direct assay" chromatin assembly or disassembly ; GO:0006333 | non-traceable author statement nucleosome mobilization ; GO:0042766 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay "CHD-3, chd3, CG9594, DmCHD3, CHD3, Chd3, dCHD3" "IPR000330:SNF2-related, N-terminal domain, IPR000953:Chromo/chromo shadow domain, IPR001650:Helicase, C-terminal, IPR001965:Zinc finger, PHD-type, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR023780:Chromo domain, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR009463:Domain of unknown function DUF1087, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR016197:Chromo domain-like" CG9594 11-Aug-17 DroID_v2017_08 "Drer\chd4a, Drer\chd3, Drer\phf21b, Drer\chd4b, Drer\phf21aa, Drer\chd5, Drer\phf21ab, Drer\chd6" Scer\CHD1 "Cele\chd-3, Cele\let-418" "Xtro\chd5, Xtro\chd3, Xtro\chd4, Xtro\chd8" "Mmus\Chd2, Mmus\Phf21b, Mmus\Chd4, Mmus\Chd8, Mmus\Chd1, Mmus\Chd6, Mmus\Chd5, Mmus\Chd3" "Hsap\CHD5, Hsap\CHD3, Hsap\CHD8, Hsap\CHD1, Hsap\CHD4, Hsap\CHD6, Hsap\CHD2" "viable,fertile,visible" trichogen cell FBgn0005332 pilX pilosus on X chromosome http://flybase.org/reports/FBgn0005332 - gene - - - "pil-X, pilX" - - 11-Aug-17 DroID_v2017_08 - - - - - - abdominal sternite 6 FBgn0004484 l(1)air11 lethal aberrant immune response 11 http://flybase.org/reports/FBgn0004484 - gene - - - "air11, l(1)air[11], l(1)air11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass,embryonic/larval lymph gland" FBgn0044348 l(2)a4 lethal (2) a4 http://flybase.org/reports/FBgn0044348 gene - - - l(2)a4 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028334 l(1)G0273 lethal (1) G0273 http://flybase.org/reports/FBgn0028334 gene - - - l(1)G0273 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027097 31B8 31B8 http://flybase.org/reports/FBgn0027097 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 31B8 - - 11-Aug-17 DroID_v2017_08 - - - - - - border follicle cell FBgn0052835 CR32835 - http://flybase.org/reports/FBgn0052835 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs16h07, CG32835, CR32835" - CR32835 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029148 NHP2 NHP2 http://flybase.org/reports/FBgn0029148 protein_coding_gene box H/ACA snoRNA binding ; GO:0034513 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 snoRNA binding ; GO:0030515 | inferred from sequence or structural similarity with UniProtKB:P32495 cleavage involved in rRNA processing ; GO:0000469 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 rRNA pseudouridine synthesis ; GO:0031118 | inferred from sequence or structural similarity with UniProtKB:P32495 maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 cellular response to starvation ; GO:0009267 | inferred from expression pattern snRNA pseudouridine synthesis ; GO:0031120 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 rRNA pseudouridine synthesis ; GO:0031118 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 box H/ACA snoRNP complex ; GO:0031429 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 small nucleolar ribonucleoprotein complex ; GO:0005732 | inferred from sequence or structural similarity with UniProtKB:P32495 "CG5258, FBgn0029148, NHP2" "IPR018492:Ribosomal protein L7Ae/L8/Nhp2 family, IPR004038:Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR029064:50S ribosomal protein L30e-like" CG5258 11-Aug-17 DroID_v2017_08 Drer\nhp2 "Scer\PLM2, Scer\NHP2" Cele\Y48A6B.3 Xtro\nhp2 Mmus\Nhp2 Hsap\NHP2 "viable,visible" trichogen cell DRSC24264 K -0.31946564 0.155569324 0.104863437 0.72879674 0.671270179 1.538756541 FBgn0010113 hdc headcase http://flybase.org/reports/FBgn0010113 FBgn0013599 protein_coding_gene - "neurogenesis ; GO:0022008 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | traceable author statement instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype regulation of neuron remodeling ; GO:1904799 | inferred from mutant phenotype negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | traceable author statement axon extension ; GO:0048675 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | non-traceable author statement branch fusion, open tracheal system ; GO:0035147 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement dendrite ; GO:0030425 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "hdc, psg12, Hdc, l(3)B4-3-20, CG15532, headcase" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR026066:Headcase protein, IPR031947:Headcase, middle domain" CG15532 11-Aug-17 DroID_v2017_08 Drer\heca - "Cele\B0238.9, Cele\cri-1" Xtro\heca Mmus\Heca Hsap\HECA " embryonic stage--larval stage , embryonic stage " " imaginal disc

, embryonic/larval spiracular branch

, imaginal ring

, embryonic central nervous system

, imaginal disc | primordia

, imaginal tracheoblast

, histoblast

" embryonic stage " imaginal tracheoblast

, imaginal disc

, embryonic/larval ventral anastomosis

, imaginal ring

, embryonic/larval dorsal anastomosis

, histoblast

" "female sterile,lethal,recessive,neuroanatomy defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,phototaxis defective,viable,visible" "embryonic/larval salivary gland,embryonic/larval trachea,axon | somatic clone | third instar larval stage,rhabdomere,somatic clone,head,antenna,head & cuticle,central nervous system,somatic muscle,tracheal system,wing,haltere,leg,epidermis,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,dorsal branch | embryonic stage,dorsal branch | third instar larval stage,tracheole" FBgn0024601 rambl rambling http://flybase.org/reports/FBgn0024601 - gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available rambl - - 11-Aug-17 DroID_v2017_08 - - - - - - viable Bolwig nerve FBgn0040261 Ugt36Bb Ugt36Bb http://flybase.org/reports/FBgn0040261 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "Ugt36Bb, CG13271, AC 005121B" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG13271 11-Aug-17 DroID_v2017_08 "Drer\ugt5f1, Drer\ugt5a4, Drer\ugt5a2, Drer\ugt5b1, Drer\zgc:172315, Drer\ugt2b6, Drer\ugt2a2, Drer\ugt5a5, Drer\ugt5a1, Drer\ugt5b2, Drer\ugt5e1, Drer\ugt1b3, Drer\ugt5c3, Drer\ugt5c2, Drer\ugt1ab, Drer\ugt1b5, Drer\ugt5b6, Drer\ugt1b2, Drer\ugt5c1, Drer\ugt2b5, Drer\ugt5g2, Drer\ugt5g1, Drer\ugt2b1, Drer\ugt2b3, Drer\ugt1b4, Drer\ugt8, Drer\ugt1b7, Drer\ugt2a5, Drer\ugt2a6, Drer\ugt5b3, Drer\ugt5d1" Scer\ATG26 "Cele\ugt-8, Cele\ugt-41, Cele\ugt-53, Cele\ugt-60, Cele\ugt-42, Cele\ugt-20, Cele\ugt-54, Cele\ugt-7, Cele\ugt-26, Cele\C55H1.1, Cele\F10D2.8, Cele\ugt-38, Cele\ugt-62, Cele\ugt-59, Cele\C03A7.13, Cele\ugt-12, Cele\ugt-35, Cele\ugt-13, Cele\ugt-15, Cele\ugt-50, Cele\ugt-46, Cele\ugt-16, Cele\ugt-28, Cele\ugt-6, Cele\H23N18.4, Cele\ugt-43, Cele\C23G10.6, Cele\K04A8.10, Cele\ugt-56, Cele\ugt-23, Cele\ugt-18, Cele\C03A7.12, Cele\ugt-30, Cele\ugt-47, Cele\ugt-22, Cele\ugt-32, Cele\ugt-14, Cele\ugt-3, Cele\ugt-24, Cele\Y43D4A.2, Cele\ugt-2, Cele\ugt-44, Cele\ugt-61, Cele\ugt-58, Cele\ugt-52, Cele\ugt-45, Cele\ugt-37, Cele\ugt-10, Cele\ugt-21, Cele\ugt-11, Cele\ugt-57, Cele\ugt-25, Cele\ugt-27, Cele\ugt-55, Cele\ugt-31, Cele\ugt-48, Cele\ugt-39, Cele\ugt-40, Cele\ugt-5, Cele\ugt-36, Cele\ugt-49, Cele\ugt-29, Cele\ugt-34, Cele\ugt-33, Cele\ugt-1, Cele\ugt-4, Cele\ugt-17, Cele\ugt-19, Cele\ugt-9, Cele\ugt-51" "Xtro\ugt2a1, Xtro\ugt2b4, Xtro\ugt3a2, Xtro\ugt1a6, Xtro\ugt8" "Mmus\Ugt1a7c, Mmus\Ugt3a1, Mmus\Ugt1a9, Mmus\Ugt3a2, Mmus\Ugt1a2, Mmus\Ugt1a5, Mmus\Ugt2b5, Mmus\Ugt2b37, Mmus\Ugt2a1, Mmus\Ugt2b35, Mmus\Ugt2b38, Mmus\Ugt1a6b, Mmus\Ugt2a3, Mmus\Ugt8a, Mmus\Ugt2b34, Mmus\Ugt2b1, Mmus\Ugt2b36, Mmus\Ugt1a1" "Hsap\UGT2B28, Hsap\UGT1A9, Hsap\UGT2A2, Hsap\UGT8, Hsap\UGT1A10, Hsap\UGT1A7, Hsap\UGT1A5, Hsap\UGT1A8, Hsap\UGT1A3, Hsap\UGT1A1, Hsap\UGT3A2, Hsap\UGT1A6, Hsap\UGT3A1, Hsap\UGT2B4, Hsap\UGT2B10, Hsap\UGT2B7, Hsap\UGT1A4, Hsap\UGT2B11, Hsap\UGT2A3, Hsap\UGT2B15, Hsap\UGT2B17" viable FBgn0265668 CG44475 - http://flybase.org/reports/FBgn0265668 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44475 - CG44475 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028102 l(3)S072611 lethal (3) S072611 http://flybase.org/reports/FBgn0028102 gene - - - "0726/11, l(3)S072611" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015450 l(1)9Fj lethal (1) 9Fj http://flybase.org/reports/FBgn0015450 - gene - - - l(1)9Fj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060339 l(3)S144301b lethal (3) S144301b http://flybase.org/reports/FBgn0060339 gene - - - "1443/01, l(3)S144301b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0024737 Mob Modifier of B1-12 http://flybase.org/reports/FBgn0024737 - gene - - - "Mob[1], Mob" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039520 Gr98a Gustatory receptor 98a http://flybase.org/reports/FBgn0039520 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr98B4, 98B.4, GR98B.4, CG13976, Gr98a, GR98a" IPR013604:7TM chemoreceptor CG13976 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - viable FBgn0032840 sNPF short neuropeptide F precursor http://flybase.org/reports/FBgn0032840 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity hormone activity ; GO:0005179 | non-traceable author statement neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with sNPF-R neuropeptide hormone activity ; GO:0005184 | inferred from direct assay adult feeding behavior ; GO:0008343 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay regulation of trehalose metabolic process ; GO:0090062 | inferred from mutant phenotype regulation of response to food ; GO:0032095 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from sequence or structural similarity determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype positive regulation of insulin receptor signaling pathway ; GO:0046628 | inferred from mutant phenotype multicellular organism growth ; GO:0035264 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from expression pattern regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype neuronal cell body ; GO:0043025 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "sNPF-4, sNPF-3, sNPF-2s, sNPF-2, sNPF-1, Drm-sNPF-AP1, Drm-sNPF, Drm-sNPF-1, sNPF1, Drm-sNPF-4, Drm-sNPF-3, Drm-sNPF-2, 38B.2, CG13968, LRLRFamide, sNPF, snpf, lrlrfa, s-NPF, sNPF3, sNPF-1[4-11], sNPF-2[12-19], short NPF, SNPF, sNPF1[1-11], sNPF1[4-11, sNPF2[12-19]" - CG13968 11-Aug-17 DroID_v2017_08 - - - - - - "large body,small body,decreased cell size,feeding behavior defective,long lived,locomotor behavior defective,male,female,increased cell size" embryonic/larval fat body FBgn0026714 kub kubel http://flybase.org/reports/FBgn0026714 - gene molecular_function ; GO:0003674 | no biological data available central nervous system development ; GO:0007417 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available kub - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic/larval central nervous system,commissure,midline glial cell,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron" FBgn0040140 l(1)G0490 lethal (1) G0490 http://flybase.org/reports/FBgn0040140 gene - - - l(1)G0490 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0050460 CG30460 - http://flybase.org/reports/FBgn0050460 protein_coding_gene - - - "CG15607, CG15608, anon-WO0140519.237, CG30460" IPR026319:Zinc finger C2HC domain-containing protein CG30460 11-Aug-17 DroID_v2017_08 Drer\zc2hc1a - "Cele\M153.4, Cele\C01H6.3" "Xtro\zc2hc1a, Xtro\zc2hc1c" "Mmus\Zc2hc1b, Mmus\Zfp474, Mmus\Zc2hc1c, Mmus\Zc2hc1a" "Hsap\ZC2HC1B, Hsap\ZNF474, Hsap\ZC2HC1A, Hsap\ZC2HC1C" viable FBgn0020852 ful fuliginosus http://flybase.org/reports/FBgn0020852 - gene - - - ful - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,body color defective" wing FBgn0061484 rover\env rover element env http://flybase.org/reports/FBgn0061484 transposable_element_gene - - - rover\env IPR022048:Envelope fusion protein-like - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011052 l(1)Q5 lethal (1) Q5 http://flybase.org/reports/FBgn0011052 FBgn0010210 gene - - - l(1)Q5 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065092 snmRNA:438 small non-messenger RNA 438 http://flybase.org/reports/FBgn0065092 non_protein_coding_gene - - - "Dm-438, CR33660, snmRNA:438" - CR33660 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065811 l(2)SH0384 lethal (2) SH0384 http://flybase.org/reports/FBgn0065811 gene - - - "l(2)SH0384, l(2)SH2 0384" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000046 Act87E Actin 87E http://flybase.org/reports/FBgn0000046 FBgn0038154 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity histone exchange ; GO:0043486 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity lipid particle ; GO:0005811 | inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay actin filament ; GO:0005884 | inferred from sequence or structural similarity "Actin87E, Actin, CG18290, actin, E, mus87E, act 87E, act87E, Act87E, Act87e, ArpC" "IPR004000:Actin family, IPR004001:Actin, conserved site, IPR020902:Actin/actin-like conserved site" CG18290 11-Aug-17 DroID_v2017_08 "Drer\acta1a, Drer\actr1, Drer\actc1a, Drer\si:ch211-241j12.3, Drer\zgc:86709, Drer\zgc:86725, Drer\acta2, Drer\si:ch73-187m15.4, Drer\actb2, Drer\actb1, Drer\ankrd52b, Drer\actc1b, Drer\actr10, Drer\acta1b" "Scer\ARP9, Scer\ACT1, Scer\ARP1" "Cele\act-5, Cele\act-2, Cele\act-3, Cele\act-4, Cele\arp-1, Cele\act-1" "Xtro\acta2, Xtro\actc1, Xtro\act3, Xtro\actb, Xtro\actr10, Xtro\acta1, Xtro\actg1, Xtro\actr1a, Xtro\ankrd52" "Mmus\Actr10, Mmus\Actl7b, Mmus\Actl11, Mmus\Actr1b, Mmus\Actc1, Mmus\Actbl2, Mmus\Actl7a, Mmus\Actr1a, Mmus\Acta2, Mmus\Actrt2, Mmus\Actg1, Mmus\Acta1, Mmus\Actg2, Mmus\Actb, Mmus\Actl10, Mmus\Actl9, Mmus\Actrt3, Mmus\Actrt1" "Hsap\ACTL7A, Hsap\POTEI, Hsap\ACTR10, Hsap\ACTL10, Hsap\ACTRT2, Hsap\ACTRT3, Hsap\ACTG1, Hsap\ACTBL2, Hsap\ACTC1, Hsap\POTEG, Hsap\ACTG2, Hsap\ACTB, Hsap\ACTL8, Hsap\POTEF, Hsap\ACTA1, Hsap\ACTRT1, Hsap\POTED, Hsap\ACTA2, Hsap\ACTR1A, Hsap\POTEJ, Hsap\POTEB, Hsap\ACTR1B, Hsap\POTEA, Hsap\POTEH, Hsap\POTEC, Hsap\POTEE, Hsap\ACTL7B, Hsap\POTEB2, Hsap\ACTL9" larval stage larval muscle system

FBgn0085062 EP1324 EP1324 http://flybase.org/reports/FBgn0085062 gene - - - EP1324 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050493 CG30493 - http://flybase.org/reports/FBgn0050493 protein_coding_gene lipid binding ; GO:0008289 | inferred from biological aspect of ancestor with PANTHER:PTN000484410 ubiquinone biosynthetic process ; GO:0006744 | inferred from biological aspect of ancestor with PANTHER:PTN000484410 ubiquinone biosynthetic process ; GO:0006744 | inferred from sequence or structural similarity with UniProtKB:Q05779 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000484410 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q05779 "CG1952, CG30493" "IPR012762:Ubiquinone biosynthesis protein COQ9, IPR013718:COQ9" CG30493 11-Aug-17 DroID_v2017_08 Drer\coq9 Scer\COQ9 - Xtro\coq9 Mmus\Coq9 Hsap\COQ9 viable FBgn0039347 CG5071 - http://flybase.org/reports/FBgn0039347 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130" intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR000315 cellular_component ; GO:0005575 | no biological data available "BcDNA:AT31683, CG5071" "IPR000315:B-box-type zinc finger, IPR001841:Zinc finger, RING-type, IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR017907:Zinc finger, RING-type, conserved site, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029000:Cyclophilin-like domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5071 11-Aug-17 DroID_v2017_08 "Drer\ppie, Drer\ppifb, Drer\ppifa, Drer\ppiab, Drer\ppiaa" "Scer\CPR1, Scer\CWC27, Scer\CPR3" Cele\T22F3.12 "Xtro\LOC100489639, Xtro\LOC101730305, Xtro\ppif, Xtro\LOC100498595, Xtro\LOC100124771, Xtro\LOC100490741, Xtro\ppie, Xtro\LOC100491243, Xtro\LOC100489074, Xtro\MGC79670, Xtro\LOC105945814, Xtro\LOC779483, Xtro\trim72, Xtro\LOC100489697, Xtro\LOC100486056, Xtro\LOC100495443, Xtro\trim13, Xtro\LOC100488741, Xtro\LOC105947556, Xtro\ppia, Xtro\LOC100498391" "Mmus\Ppia, Mmus\Ppif, Mmus\Ppie, Mmus\Ranbp2" "Hsap\PPIAL4G, Hsap\PPIF, Hsap\PPIAL4A, Hsap\TRIM35, Hsap\PPIAL4C, Hsap\PPIAL4E, Hsap\LOC105371242, Hsap\RANBP2, Hsap\PPIE, Hsap\PPIA, Hsap\PPIAL4F, Hsap\PPIAL4D" viable FBgn0036487 Prp31 Pre-mRNA processing factor 31 http://flybase.org/reports/FBgn0036487 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:15446 ribonucleoprotein complex binding ; GO:0043021 | inferred from sequence or structural similarity with HGNC:15446 "spliceosomal tri-snRNP complex assembly ; GO:0000244 | inferred from electronic annotation with InterPro:IPR027105 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000357441 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000003323 inferred from sequence or structural similarity with protein_id:CAB43677" U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from electronic annotation with InterPro:IPR027105 spliceosomal tri-snRNP complex ; GO:0097526 | inferred from biological aspect of ancestor with PANTHER:PTN000357441 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000003323 inferred from sequence or structural similarity with protein_id:CAB43677 U4atac snRNP ; GO:0005690 | inferred from biological aspect of ancestor with PANTHER:PTN000357441 U4 snRNP ; GO:0005687 | inferred from biological aspect of ancestor with PANTHER:PTN000357441 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "clone 2.38, anon-EST:Liang-2.38, FBgn0036487, Prp31, CG6876" "IPR002687:Nop domain, IPR012976:NOSIC, IPR027105:U4/U6 small nuclear ribonucleoprotein Prp31, IPR019175:Prp31 C-terminal" CG6876 11-Aug-17 DroID_v2017_08 Drer\prpf31 Scer\PRP31 Cele\prp-31 Xtro\prpf31 Mmus\Prpf31 Hsap\PRPF31 "visible,lethal,neuroanatomy defective,partially lethal - majority die" "eye,rhabdomereey.PU,pigment cell,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC10735 E 1.376649186 0.684422679 -0.27098361 2.017759526 -0.432992994 -0.917730992 FBgn0266641 CR45148 - http://flybase.org/reports/FBgn0266641 non_protein_coding_gene - - - "CR45148, lincRNA.368" - CR45148 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263912 piRNA piwi-associated RNA http://flybase.org/reports/FBgn0263912 gene_group - - - piRNA - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029679 CG2901 - http://flybase.org/reports/FBgn0029679 protein_coding_gene - synaptic target recognition ; GO:0008039 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004342 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000081883 CG2901 "IPR004331:SPX domain, IPR004342:EXS, C-terminal" CG2901 11-Aug-17 DroID_v2017_08 "Drer\xpr1a, Drer\xpr1b" "Scer\VTC2, Scer\VTC4, Scer\SYG1, Scer\ERD1, Scer\VTC3" Cele\Y39A1A.22 Xtro\xpr1 Mmus\Xpr1 Hsap\XPR1 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0259245 DIP-beta Dpr-interacting protein beta http://flybase.org/reports/FBgn0259245 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "pp-CT34320, CG12564, pp-CT34321, BcDNA:RE23430, CG12565, pp-CT34319, CT34319, CG14583, BP1062, CG34019, 42343, DIP-beta, CG42343" "IPR007110:Immunoglobulin-like domain, IPR003598:Immunoglobulin subtype 2, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype, IPR013098:Immunoglobulin I-set" CG42343 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-215e19.3, Drer\LOC108191960, Drer\zgc:123297, Drer\ntm, Drer\jam3a, Drer\pigrl4.2, Drer\f11r.1, Drer\zgc:153911, Drer\negr1, Drer\zgc:162154, Drer\mxra8a, Drer\vsig8b, Drer\cxadr, Drer\zgc:172120, Drer\gpa33, Drer\esamb, Drer\si:zfos-1011f11.1, Drer\esama, Drer\opcml, Drer\vtcn1, Drer\cxcr3.1, Drer\sc:d0835, Drer\igsf11, Drer\si:dkey-65b12.12, Drer\lsamp, Drer\vsig8a, Drer\jam2a, Drer\si:dkey-250k15.10, Drer\jam2b, Drer\f11r.2, Drer\jam3b, Drer\zgc:110372, Drer\LOC100151468, Drer\LOC797620, Drer\zgc:112965, Drer\zgc:153073, Drer\mxra8b, Drer\si:ch211-9d9.7" - Cele\rig-5 "Xtro\cd276, Xtro\ntm, Xtro\negr1, Xtro\vtcn1, Xtro\lsamp, Xtro\LOC100497709, Xtro\btn2a2" "Mmus\Negr1, Mmus\Gm5155, Mmus\Ermap, Mmus\Igsf11, Mmus\Cd276, Mmus\Hepacam2, Mmus\Gpa33, Mmus\Icosl, Mmus\Psg21, Mmus\Cd86, Mmus\Cd274, Mmus\Btnl2, Mmus\Ceacam5, Mmus\Mxra8, Mmus\Psg29, Mmus\Psg19, Mmus\Vsig2, Mmus\Jam3, Mmus\Psg17, Mmus\Skint8, Mmus\Vsig1, Mmus\Igsf5, Mmus\Iglon5, Mmus\Vsir, Mmus\Lsamp, Mmus\Esam, Mmus\Skint4, Mmus\Psg26, Mmus\Cd80, Mmus\Cxadr, Mmus\Skint3, Mmus\Btnl9, Mmus\Btn1a1, Mmus\F11r, Mmus\Psg28, Mmus\Ceacam18, Mmus\Skint1, Mmus\Tapbpl, Mmus\Clmp, Mmus\Psg25, Mmus\Btn2a2, Mmus\Opcml, Mmus\Psg18, Mmus\Gm1123, Mmus\Vtcn1, Mmus\Btnl10, Mmus\Ntm, Mmus\Skint2, Mmus\Pdcd1lg2, Mmus\Psg23, Mmus\Psg22, Mmus\Ceacam16, Mmus\Jam2, Mmus\Psg27, Mmus\Vsig8" "Hsap\VSIG2, Hsap\OPCML, Hsap\ESAM, Hsap\C10orf54, Hsap\MXRA8, Hsap\BTN2A1, Hsap\PSG1, Hsap\NEGR1, Hsap\PSG6, Hsap\NTM, Hsap\CD80, Hsap\F11R, Hsap\MOG, Hsap\CD86, Hsap\PDCD1LG2, Hsap\LOC102723996, Hsap\BTN2A2, Hsap\BTN1A1, Hsap\BTNL2, Hsap\BTN3A1, Hsap\CXADR, Hsap\IGLON5, Hsap\IGSF5, Hsap\CD276, Hsap\BTN3A2, Hsap\LSAMP, Hsap\BTNL3, Hsap\CD274, Hsap\NCR3LG1, Hsap\VSIG8, Hsap\GPA33, Hsap\C1orf204, Hsap\ERMAP, Hsap\VSIG10L, Hsap\JAM3, Hsap\IGSF11, Hsap\JAM2, Hsap\VTCN1, Hsap\CLMP, Hsap\BTNL8, Hsap\BTNL9, Hsap\HHLA2, Hsap\VSIG1" FBgn0060326 l(3)S146604b lethal (3) S146604b http://flybase.org/reports/FBgn0060326 gene - - - "1466/04, l(3)S146604b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0015886 anon-66Ba anon-66Ba http://flybase.org/reports/FBgn0015886 - gene - - - anon-66Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039354 Lgr3 Leucine-rich repeat-containing G protein-coupled receptor 3 http://flybase.org/reports/FBgn0039354 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from direct assay insulin-like growth factor binding ; GO:0005520 | inferred from physical interaction with Ilp8 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model protein-hormone receptor activity ; GO:0016500 | inferred from sequence or structural similarity G-protein coupled peptide receptor activity ; GO:0008528 | inferred from biological aspect of ancestor with PANTHER:PTN001224574 hormone-mediated signaling pathway ; GO:0009755 | inferred from biological aspect of ancestor with PANTHER:PTN001224574 adenylate cyclase-activating G-protein coupled receptor signaling pathway ; GO:0007189 | inferred from biological aspect of ancestor with PANTHER:PTN001224574 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model regulation of developmental growth ; GO:0048638 | inferred from genetic interaction with Ilp8 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity cAMP-mediated signaling ; GO:0019933 | inferred from direct assay activation of adenylate cyclase activity ; GO:0007190 | inferred from biological aspect of ancestor with PANTHER:PTN001224574 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001224574 "Lgr3, CG5046, CG5042, CT16193, CG31096, anon-WO0170980.26, anon-WO0170980.25, DLGR3, dLGR3, lgr3" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001611:Leucine-rich repeat, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR008112:Relaxin receptor, IPR017452:GPCR, rhodopsin-like, 7TM, IPR032675:Leucine-rich repeat domain, L domain-like, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR034298:TSH/LHCG/FSH receptor" CG31096 11-Aug-17 DroID_v2017_08 "Drer\rxfp1, Drer\rxfp2l, Drer\fshr, Drer\rxfp2b, Drer\tshr, Drer\lhcgr, Drer\rxfp2a, Drer\lgr4, Drer\lrrc57" Scer\SOG2 "Cele\ZK546.2, Cele\fshr-1" "Xtro\fshr, Xtro\tshr, Xtro\lrrc57, Xtro\rxfp1, Xtro\rxfp2" "Mmus\Lhcgr, Mmus\Lrrc57, Mmus\Lgr6, Mmus\Fshr, Mmus\Lgr5, Mmus\Rxfp2, Mmus\Lgr4, Mmus\Rxfp1, Mmus\Tshr" "Hsap\LGR4, Hsap\LGR6, Hsap\LHCGR, Hsap\LRRC57, Hsap\RXFP1, Hsap\RXFP2, Hsap\FSHR, Hsap\TSHR, Hsap\LGR5" FBgn0005208 l(3)gl lethal (3) giant larvae http://flybase.org/reports/FBgn0005208 - gene - - - "l(3)giant larvae, l(3)gl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "fat body,embryonic/larval brain,imaginal disc" FBgn0065530 l(2)SH1110 lethal (2) SH1110 http://flybase.org/reports/FBgn0065530 gene - - - "l(2)SH1110, l(2)SH2 1110" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052218 CR32218 - http://flybase.org/reports/FBgn0052218 non_protein_coding_gene - - - "CG8037, CR32218" - CR32218 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041090 upd-like upd-like http://flybase.net/reports/FBgn0041090.html gene 11-Aug-17 DroID_v2017_08 FBgn0026160 tna tonalli http://flybase.org/reports/FBgn0026160 "FBgn0011498, FBgn0024566, FBgn0028123, FBgn0036103, FBgn0061852" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181 chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from genetic interaction with brm inferred from genetic interaction with Pc inferred from genetic interaction with Scr inferred from genetic interaction with Antp inferred from genetic interaction with osa inferred from genetic interaction with kis nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay "CG7958, l(3)rI075, 0583/02, l(3)L6731, l(3)S058302, anon-WO0118547.590, tna" "IPR004181:Zinc finger, MIZ-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG7958 11-Aug-17 DroID_v2017_08 "Drer\pias1b, Drer\pias4a, Drer\pias1a, Drer\zmiz1a, Drer\pias4b, Drer\pias2, Drer\zmiz2, Drer\LOC103911965" "Scer\NFI1, Scer\SIZ1" "Cele\miz-1, Cele\gei-17" "Xtro\zmiz1, Xtro\pias4, Xtro\zmiz2, Xtro\pias1, Xtro\pias2, Xtro\pias3" "Mmus\Pias2, Mmus\Pias3, Mmus\Pias4, Mmus\Zmiz2, Mmus\Zmiz1, Mmus\Pias1" "Hsap\ZMIZ2, Hsap\PIAS4, Hsap\PIAS3, Hsap\PIAS1, Hsap\PIAS2, Hsap\ZMIZ1" "visible,lethal - all die before end of larval stage,rescuable maternal effect,some die during larval stage,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,dominant,viable" "sex comb,haltere,wing,ectopic,mesothoracic tergum" FBgn0043825 CG18284 - http://flybase.org/reports/FBgn0043825 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483 lipase activity ; GO:0016298 | inferred from sequence or structural similarity" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern lipid metabolic process ; GO:0006629 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "Acp, BEST:GH10507, CG18284" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG18284 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH2, Scer\YEH1, Scer\TGL1" "Cele\lipl-7, Cele\lipl-2, Cele\lipl-4, Cele\lipl-8, Cele\lipl-1, Cele\lipl-3, Cele\lipl-6, Cele\lipl-5" Xtro\lipa "Mmus\Lipa, Mmus\Lipo3, Mmus\Lipo4, Mmus\Lipf, Mmus\Lipn, Mmus\Lipo2, Mmus\Lipk, Mmus\Lipm, Mmus\Lipo1" "Hsap\LIPA, Hsap\LIPK, Hsap\LIPJ, Hsap\LIPN, Hsap\LIPM, Hsap\LIPF" DRSC02661 K 0.954721466 0.326033149 -0.700589086 0.302347587 -0.895418467 -1.756131656 FBgn0085508 CG40682 - http://flybase.org/reports/FBgn0085508 protein_coding_gene - - - CG40682 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017396 l(1)10Bq lethal (1) 10Bq http://flybase.org/reports/FBgn0017396 - gene - - - "HM10, l(1)10Bq" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263876 J16 - http://flybase.org/reports/FBgn0263876 gene - - - J16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,somatic clone" "embryonic/larval neuroblast,somatic clone,embryonic/larval brain" FBgn0265729 CR44536 - http://flybase.org/reports/FBgn0265729 non_protein_coding_gene - - - "CR44536, incRNA.417, lincRNA.417" - CR44536 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083280 E(smoDN)2281 Enhancer of smoDN 2281 http://flybase.org/reports/FBgn0083280 gene - - - E(smoDN)2281 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086419 l(3)CHc lethal (3) CHc http://flybase.org/reports/FBgn0086419 gene - - - l(3)CHc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041617 SM3-3 SM3-3 http://flybase.org/reports/FBgn0041617 gene - - - SM3-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015464 l(2)37Dl lethal (2) 37Dl http://flybase.org/reports/FBgn0015464 - gene - - - "l(2)E34, l(2)E34M, l(2)37Dl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263454 CR43477 - http://flybase.org/reports/FBgn0263454 non_protein_coding_gene - - - CR43477 - CR43477 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260244 GSd324 - http://flybase.org/reports/FBgn0260244 gene - - - GSd324 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267686 CR46022 - http://flybase.org/reports/FBgn0267686 non_protein_coding_gene - - - CR46022 - CR46022 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065515 l(2)SH1155 lethal (2) SH1155 http://flybase.org/reports/FBgn0065515 gene - - - "l(2)SH1155, l(2)SH2 1155" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020878 anon-A34 anon-A34 http://flybase.org/reports/FBgn0020878 - gene - - - "2-A34, anon-A34" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0010862 l(3)05241 lethal (3) 05241 http://flybase.org/reports/FBgn0010862 - gene - - - l(3)05241 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0015232 GpHLH Glial precursor HLH protein http://flybase.org/reports/FBgn0015232 - gene - - - "GPHLH, GpHLH" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015992 l(2)k05422a lethal (2) k05422a http://flybase.org/reports/FBgn0015992 - gene - - - "l(2)k05422, l(2)k05422a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" presumptive embryonic/larval peripheral nervous system FBgn0031038 Tyler Tyler http://flybase.org/reports/FBgn0031038 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG33075, CG14208, Tyler" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG14208 11-Aug-17 DroID_v2017_08 "Drer\slc25a38a, Drer\slc25a39, Drer\slc25a40" "Scer\HEM25, Scer\MTM1" Cele\C16C10.1 "Xtro\slc25a40, Xtro\slc25a39" "Mmus\Slc25a38, Mmus\Slc25a40, Mmus\Slc25a39" "Hsap\SLC25A39, Hsap\SLC25A38, Hsap\SLC25A40" FBgn0036940 obst-J obstructor-J http://flybase.org/reports/FBgn0036940 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "anon-EST:ParkEST360, obst-J, CG7348" IPR002557:Chitin binding domain CG7348 11-Aug-17 DroID_v2017_08 - - "Cele\cpg-2, Cele\R02F2.4, Cele\dct-9, Cele\cbd-1" - - - viable FBgn0036793 CG4174 - http://flybase.org/reports/FBgn0036793 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 CG4174 "IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG4174 11-Aug-17 DroID_v2017_08 "Drer\zgc:158254, Drer\p4ha2, Drer\p4ha1a, Drer\p4ha3, Drer\zgc:152670, Drer\p4ha1b, Drer\p4htm" - "Cele\phy-4, Cele\phy-3, Cele\Y43F8B.19, Cele\C14E2.4, Cele\phy-2" "Xtro\p4ha2, Xtro\p4ha3, Xtro\p4ha1" "Mmus\P4htm, Mmus\P4ha2, Mmus\P4ha3, Mmus\P4ha1" "Hsap\P4HA2, Hsap\P4HTM, Hsap\P4HA3, Hsap\P4HA1" FBgn0053360 5SrRNA:CR33360 5SrRNA:CR33360 http://flybase.org/reports/FBgn0053360 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33360, 5SrRNA:CR33360" - CR33360 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041712 yellow-d yellow-d http://flybase.org/reports/FBgn0041712 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG9889, BcDNA:GH20107, yellow-d, yell-d, d" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG9889 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\C24H12.1, Cele\T27A1.3, Cele\fbxa-76, Cele\F49E11.8" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 "viable,visible" trichogen cell FBgn0263962 BG01701 - http://flybase.org/reports/FBgn0263962 gene - - - BG01701 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0015460 l(2)37CDe lethal (2) 37CDe http://flybase.org/reports/FBgn0015460 - gene - - - "l(2)E107, l(2)37CDe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036795 CG18233 - http://flybase.org/reports/FBgn0036795 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 oxidoreductase activity ; GO:0016491 | inferred from sequence model" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 cellular_component ; GO:0005575 | no biological data available CG18233 "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG18233 11-Aug-17 DroID_v2017_08 "Drer\p4ha2, Drer\zgc:158254, Drer\p4htm, Drer\p4ha3, Drer\zgc:152670, Drer\p4ha1b, Drer\p4ha1a" - "Cele\Y43F8B.19, Cele\phy-3, Cele\phy-4, Cele\C14E2.4, Cele\phy-2" "Xtro\p4ha2, Xtro\p4ha1, Xtro\p4ha3" "Mmus\P4ha1, Mmus\P4ha3, Mmus\P4htm, Mmus\P4ha2" "Hsap\P4HA2, Hsap\P4HTM, Hsap\P4HA1, Hsap\P4HA3" viable FBgn0028262 l(2)k16716 lethal (2) k16716 http://flybase.org/reports/FBgn0028262 gene - - - l(2)k16716 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040360 CG14626 - http://flybase.org/reports/FBgn0040360 protein_coding_gene - - - "EG:BACR42I17.6, CG14626" - CG14626 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001227 Hsp67Ba Heat shock gene 67Ba http://flybase.org/reports/FBgn0001227 FBgn0026837 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model response to heat ; GO:0009408 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "Dmel22.2, Hsp67Ba, gene1, CG4167, DROHSP, DROHSP1, gene 1, Hsp-G1, small hsp locus 67B, hsp67Ba, DmHsp67, HSP67BA" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4167 11-Aug-17 DroID_v2017_08 "Drer\hspb2, Drer\si:dkey-1k23.3, Drer\hspb15, Drer\hspb12, Drer\cryabb, Drer\hspb7, Drer\hspb1, Drer\hspb9, Drer\hspb8, Drer\cryaba, Drer\hspb6, Drer\cryaa, Drer\hspb3, Drer\hspb11" - "Cele\hsp-16.2, Cele\ZK1128.7, Cele\hsp-16.11, Cele\hsp-16.49, Cele\hsp-16.1, Cele\hsp-25, Cele\hsp-16.48, Cele\F08H9.4, Cele\hsp-12.1, Cele\sip-1, Cele\hsp-12.3, Cele\hsp-12.6, Cele\hsp-16.41, Cele\hsp-43, Cele\hsp-17, Cele\F08H9.3, Cele\hsp-12.2, Cele\Y55F3BR.6" "Xtro\cryaa, Xtro\hspb8, Xtro\cryab, Xtro\uqcrh, Xtro\hspb1, Xtro\hsp30d, Xtro\hspb3, Xtro\hspb2, Xtro\hspb6" "Mmus\Cryaa, Mmus\Hspb6, Mmus\Hspb8, Mmus\Hspb2, Mmus\Hspb1, Mmus\Hspb9, Mmus\Hspb7, Mmus\Cryab, Mmus\Hspb3" "Hsap\CRYAA, Hsap\HSPB8, Hsap\CRYAB, Hsap\HSPB9, Hsap\LOC102724652, Hsap\HSPB3, Hsap\HSPB1, Hsap\HSPB2, Hsap\HSPB6, Hsap\HSPB7" prepupal stage "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" FBgn0259872 Su(Ste):CR42441 Su(Ste):CR42441 http://flybase.org/reports/FBgn0259872 non_protein_coding_gene - - - "Su(Ste):CR42441, CR42441" - CR42441 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029113 Uba2 Ubiquitin activating enzyme 2 http://flybase.org/reports/FBgn0029113 protein_coding_gene SUMO activating enzyme activity ; GO:0019948 | inferred from electronic annotation with InterPro:IPR030661 SUMO activating enzyme activity ; GO:0019948 | inferred from sequence or structural similarity ubiquitin activating enzyme binding ; GO:0033134 | inferred from physical interaction with Aos1 positive regulation of NF-kappaB transcription factor activity ; GO:0051092 | inferred from direct assay protein sumoylation ; GO:0016925 | inferred from mutant phenotype humoral immune response ; GO:0006959 | inferred from mutant phenotype positive regulation of MyD88-dependent toll-like receptor signaling pathway ; GO:0034126 | inferred from mutant phenotype protein sumoylation ; GO:0016925 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay SUMO activating enzyme complex ; GO:0031510 | inferred from sequence or structural similarity "SAE2, sip2, DmUba2, Ubc2, Sae2, L36, CG7528, dUba2, DmSae2, Dmuba2, DmSAE2, Uba2, uba2, UBA2" "IPR000594:THIF-type NAD/FAD binding fold, IPR030661:SUMO-activating enzyme subunit SAE2/Uba2, IPR028077:Ubiquitin/SUMO-activating enzyme ubiquitin-like domain, IPR019572:Ubiquitin-activating enzyme, catalytic cysteine domain, IPR033127:Ubiquitin-activating enzyme E1, Cys active site" CG7528 11-Aug-17 DroID_v2017_08 Drer\uba2 Scer\UBA2 Cele\uba-2 Xtro\uba2 Mmus\Uba2 Hsap\UBA2 " adult stage , embryonic stage | stage 6-15 , embryonic stage | embryonic cycle 10-14 " " germarium

, organism

,

, oocyte

" "increased cell death,somatic clone,cell lethal,decreased cell number,lethal - all die before end of P-stage,recessive,some die during P-stage,lethal,female fertile,visible,temperature conditional,immune response defective,tumorigenic" "imaginal disc,optic lobe,wing disc,somatic clone,eye,ommatidium,pigment cell,temperature conditional,embryonic/larval fat body,embryonic/larval hemocoel,eye disc,adult head" FBgn0033224 Nop17l Nop17 like http://flybase.org/reports/FBgn0033224 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B axonemal dynein complex assembly ; GO:0070286 | inferred from electronic annotation with InterPro:IPR034727 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR034727 "CG1553, Nop17l" "IPR012981:PIH1 domain, IPR034727:Kintoun, IPR015943:WD40/YVTN repeat-like-containing domain" CG1553 11-Aug-17 DroID_v2017_08 "Drer\pih1d1, Drer\dnaaf2, Drer\pih1d2" Scer\PIH1 Cele\F32D8.4 "Xtro\dnaaf2, Xtro\pih1d1, Xtro\pih1d2" "Mmus\Dnaaf2, Mmus\Pih1d1, Mmus\Pih1d2" "Hsap\PIH1D2, Hsap\DNAAF2, Hsap\PIH1D1" viable "wing,posterior wing margin" FBgn0263802 CR43605 - http://flybase.org/reports/FBgn0263802 non_protein_coding_gene - - - "CR43605, CR43623" - CR43605 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262119 l(2)NC195 - http://flybase.org/reports/FBgn0262119 gene - - - l(2)NC195 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023469 anon-50CDa anon-50CDa http://flybase.org/reports/FBgn0023469 - gene - - - anon-50CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036402 CG6650 - http://flybase.org/reports/FBgn0036402 protein_coding_gene "phosphotransferase activity, alcohol group as acceptor ; GO:0016773 | inferred from electronic annotation with InterPro:IPR007666" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR007666 - "l(3)S067006, 0670/06, l(3)067006, anon-WO0172774.123, anon-WO0172774.122, anon-WO0172774.121, CG6650" "IPR007666:ADP-specific phosphofructokinase/glucokinase, IPR029056:Ribokinase-like" CG6650 11-Aug-17 DroID_v2017_08 "Drer\adpgk2, Drer\adpgk" - Cele\C50D2.7 "Xtro\LOC100489920, Xtro\LOC100216148" Mmus\Adpgk Hsap\ADPGK "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,viable" FBgn0032781 RtcB RtcB-like http://flybase.org/reports/FBgn0032781 protein_coding_gene RNA ligase (ATP) activity ; GO:0003972 | inferred from electronic annotation with InterPro:IPR027513 "tRNA splicing, via endonucleolytic cleavage and ligation ; GO:0006388 | inferred from electronic annotation with InterPro:IPR027513 positive regulation of tRNA processing ; GO:2000237 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" tRNA-splicing ligase complex ; GO:0072669 | inferred from electronic annotation with InterPro:IPR027513 "CG9987, RtcB" "IPR001233:tRNA-splicing ligase, RtcB, IPR027513:tRNA-splicing ligase RtcB homologue, eukaryotic" CG9987 11-Aug-17 DroID_v2017_08 Drer\rtcb - Cele\rtcb-1 Xtro\rtcb Mmus\Rtcb Hsap\RTCB "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective" "trichogen cell,mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell" FBgn0000351 cort cortex http://flybase.org/reports/FBgn0000351 FBgn0031847 protein_coding_gene ubiquitin-protein transferase activator activity ; GO:0097027 | inferred from electronic annotation with InterPro:IPR033010 anaphase-promoting complex binding ; GO:0010997 | inferred from physical interaction with Cdc27 inferred from physical interaction with Cdc16 female meiotic division ; GO:0007143 | inferred from mutant phenotype anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype homologous chromosome segregation ; GO:0045143 | traceable author statement female meiosis II ; GO:0007147 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype female meiosis I ; GO:0007144 | inferred from genetic interaction with fzy cellularization ; GO:0007349 | inferred from mutant phenotype egg activation ; GO:0007343 | inferred from mutant phenotype positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle ; GO:0051441 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "CG11330, cor, cort, Cort" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR033010:The WD repeat Cdc20/Fizzy family" CG11330 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,female sterile,recessive,meiotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female,visible,partially lethal - majority die,some die during pupal stage" "pole cell,maternal effect,wing,posterior compartment,mesothoracic tergum" FBgn0014898 anon-10Ae anon-10Ae http://flybase.org/reports/FBgn0014898 - gene - - - anon-10Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265581 CR44408 - http://flybase.org/reports/FBgn0265581 non_protein_coding_gene - - - CR44408 - CR44408 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063411 l(3)3450-L lethal (3) 3450-L http://flybase.org/reports/FBgn0063411 gene - - - l(3)3450-L - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0036910 Cyp305a1 Cyp305a1 http://flybase.org/reports/FBgn0036910 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CYP305A1-Dm, AAF49108.1, 305a1, CG8733, Cyp305a1, Cyp305A1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG8733 11-Aug-17 DroID_v2017_08 "Drer\cyp2aa3, Drer\cyp2u1, Drer\cyp2n13, Drer\cyp1a, Drer\cyp2j20, Drer\cyp2aa2, Drer\cyp2x10.2, Drer\cyp1b1, Drer\cyp2ad6, Drer\cyp2x8, Drer\cyp2aa4, Drer\cyp2k17, Drer\cyp2x6, Drer\cyp2ad2, Drer\cyp2ae1, Drer\cyp2k19, Drer\cyp2k6, Drer\cyp2p6, Drer\cyp2r1, Drer\cyp2k20, Drer\cyp2p8, Drer\cyp2k21, Drer\cyp2aa11, Drer\cyp2p9, Drer\cyp2aa12, Drer\cyp2aa1, Drer\si:dkey-286h2.7, Drer\cyp2p7, Drer\cyp2x12, Drer\cyp2p10, Drer\cyp2aa9, Drer\LOC100148115, Drer\cyp2ad3, Drer\cyp1d1, Drer\cyp2k18, Drer\cyp2k8, Drer\cyp17a1, Drer\si:zfos-411a11.2, Drer\cyp2k31, Drer\cyp2x9, Drer\cyp2k16, Drer\cyp2k22, Drer\cyp2x7, Drer\cyp17a2, Drer\cyp2y3, Drer\cyp21a2, Drer\cyp2v1, Drer\cyp2aa8" - "Cele\cyp-36A1, Cele\cyp-33A1, Cele\cyp-14A1, Cele\cyp-33D1, Cele\cyp-33E1, Cele\daf-9, Cele\cyp-14A3, Cele\cyp-33C9, Cele\cyp-33C2, Cele\cyp-33C7, Cele\cyp-33C3, Cele\cyp-14A5, Cele\cyp-33C11, Cele\cyp-14A4, Cele\cyp-33C12, Cele\cyp-33E2, Cele\cyp-33C5, Cele\cyp-33C6, Cele\cyp-33C1, Cele\cyp-14A2, Cele\cyp-23A1, Cele\cyp-33C4, Cele\cyp-33C8, Cele\cyp-33B1, Cele\cyp-33D3" "Xtro\LOC100486127, Xtro\LOC100036663, Xtro\MGC107969, Xtro\LOC100497184, Xtro\LOC100145541, Xtro\MGC69416, Xtro\LOC100497460, Xtro\cyp2c8.2, Xtro\cyp21a2.1, Xtro\LOC548374, Xtro\cyp2d6, Xtro\cyp2e1, Xtro\cyp2b6, Xtro\LOC619584, Xtro\cyp2c8.1, Xtro\cyp17a1, Xtro\LOC100145323, Xtro\cyp2r1, Xtro\LOC100145695, Xtro\cyp1a1, Xtro\LOC100145084, Xtro\cyp2a6, Xtro\cyp1b1, Xtro\cyp2w1, Xtro\cyp2g1p, Xtro\cyp2a13, Xtro\cyp2u1, Xtro\LOC100493194, Xtro\cyp1d1, Xtro\MGC69353, Xtro\cyp2f2, Xtro\cyp2j2" "Mmus\Cyp2d34, Mmus\Cyp17a1, Mmus\Cyp2j11, Mmus\Cyp2j9, Mmus\Cyp2j12, Mmus\Cyp2j5, Mmus\Cyp2g1, Mmus\Cyp2a12, Mmus\Cyp2d22, Mmus\Cyp2d40, Mmus\Cyp2w1, Mmus\Cyp2d9, Mmus\Cyp2d10, Mmus\Cyp2b23, Mmus\Cyp2d26, Mmus\Cyp2c50, Mmus\Cyp2c67, Mmus\Cyp2c40, Mmus\Cyp2b9, Mmus\Cyp2c65, Mmus\Cyp2c44, Mmus\Cyp2c54, Mmus\Cyp2e1, Mmus\Cyp2ab1, Mmus\Cyp2f2, Mmus\Cyp2b13, Mmus\Cyp2d11, Mmus\Cyp2c37, Mmus\Cyp2j8, Mmus\Cyp2s1, Mmus\Cyp2c66, Mmus\Cyp2c38, Mmus\Cyp2c29, Mmus\Cyp2j6, Mmus\Cyp2b19, Mmus\Cyp2c39, Mmus\Cyp2c55, Mmus\Cyp1a1, Mmus\Cyp2c69, Mmus\Cyp2u1, Mmus\Cyp2b10, Mmus\Cyp2j13, Mmus\Cyp1a2, Mmus\Cyp1b1, Mmus\Cyp21a1, Mmus\Cyp2a22, Mmus\Cyp2t4, Mmus\Cyp2a5, Mmus\Cyp2r1, Mmus\Cyp2c70, Mmus\Cyp2c68, Mmus\Cyp2d12, Mmus\Cyp2a4" "Hsap\CYP2F1, Hsap\CYP2A6, Hsap\CYP2A7, Hsap\CYP17A1, Hsap\CYP2B6, Hsap\CYP2W1, Hsap\CYP1A1, Hsap\CYP2C9, Hsap\CYP2R1, Hsap\CYP2A13, Hsap\CYP2J2, Hsap\CYP2D6, Hsap\CYP1A2, Hsap\CYP2E1, Hsap\CYP21A2, Hsap\CYP2C8, Hsap\CYP2C19, Hsap\CYP2S1, Hsap\CYP2U1, Hsap\CYP2C18, Hsap\CYP1B1" FBgn0002659 fs(2)51Fb female sterile (2) 51Fb http://flybase.org/reports/FBgn0002659 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)cellQL46, mat(2)cell-H, fs(2)51Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0285913 red red Malpighian tubules http://flybase.org/reports/FBgn0285913 protein_coding_gene - - - "red, CG12207, bw-l" IPR018392:LysM domain CG12207 11-Aug-17 DroID_v2017_08 "Drer\lysmd2, Drer\lysmd1" - Cele\lmd-2 "Xtro\lysmd2, Xtro\lysmd1" "Mmus\Lysmd1, Mmus\Lysmd2" "Hsap\LYSMD1, Hsap\LYSMD2" viable FBgn0267233 CR45673 - http://flybase.org/reports/FBgn0267233 non_protein_coding_gene - - - CR45673 - CR45673 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263025 CG43320 - http://flybase.org/reports/FBgn0263025 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43320, CG12879" IPR003347:JmjC domain CG43320 11-Aug-17 DroID_v2017_08 "Drer\tyw5, Drer\hif1an, Drer\hspbap1, Drer\kdm8" - - "Xtro\hif1an, Xtro\hspbap1, Xtro\kdm8" "Mmus\Hspbap1, Mmus\Tyw5, Mmus\Hif1an, Mmus\Kdm8" "Hsap\KDM8, Hsap\HIF1AN, Hsap\TYW5, Hsap\HSPBAP1" viable FBgn0029919 CG14432 - http://flybase.org/reports/FBgn0029919 protein_coding_gene - - - CG14432 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065364 l(2)SH1724 lethal (2) SH1724 http://flybase.org/reports/FBgn0065364 gene - - - "l(2)SH1724, l(2)SH2 1724" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053919 CG33919 - http://flybase.org/reports/FBgn0053919 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33919 IPR010512:Protein of unknown function DUF1091 CG33919 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083152 S(smoDN)194 Suppressor of smoDN 194 http://flybase.org/reports/FBgn0083152 gene - - - S(smoDN)194 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060707 l(3)S070503b lethal (3) S070503b http://flybase.org/reports/FBgn0060707 gene - - - "0705/03, l(3)S070503b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044097 E(rst)D151 E(rst)D151 http://flybase.org/reports/FBgn0044097 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D151, E(rst)D151" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028989 shrv shrinking violet http://flybase.org/reports/FBgn0028989 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - shrv - - 11-Aug-17 DroID_v2017_08 - - - - - - dendrite | dorsal | embryonic stage FBgn0082680 E(ftz)4038 E(ftz)4038 http://flybase.org/reports/FBgn0082680 gene - - - "4038, E(ftz)4038" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042647 elav::Rbp9 elav::Rbp9 http://flybase.org/reports/FBgn0042647 engineered_fusion_gene - - - elav::Rbp9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036510 SCCRO Squamous cell carcinoma-related oncogene http://flybase.org/reports/FBgn0036510 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with UniProtKB:Q9U3C8 ubiquitin-like protein binding ; GO:0032182 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 cullin family protein binding ; GO:0097602 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 protein neddylation ; GO:0045116 | inferred from sequence or structural similarity with UniProtKB:Q9U3C8 cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype positive regulation of ubiquitin-protein transferase activity ; GO:0051443 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 positive regulation of protein neddylation ; GO:2000436 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9U3C8 nucleus ; GO:0005634 | inferred from direct assay ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9U3C8 "CG7427, dSCCRO, SCCRO" "IPR005176:Potentiating neddylation domain, IPR009060:UBA-like, IPR014764:Defective-in-cullin neddylation protein" CG7427 11-Aug-17 DroID_v2017_08 "Drer\dcun1d2b, Drer\dcun1d5, Drer\dcun1d2a, Drer\dcun1d3, Drer\dcun1d4, Drer\dcun1d1" Scer\DCN1 Cele\dcn-1 "Xtro\dcun1d2, Xtro\dcun1d1, Xtro\dcun1d5, Xtro\dcun1d3" "Mmus\Dcun1d4, Mmus\Dcun1d5, Mmus\Dcun1d1, Mmus\Dcun1d3, Mmus\Dcun1d2" "Hsap\DCUN1D1, Hsap\DCUN1D4, Hsap\DCUN1D5, Hsap\DCUN1D3, Hsap\DCUN1D2" viable FBgn0000384 cta concertina http://flybase.org/reports/FBgn0000384 "FBan0017678, FBgn0058010" protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000469 G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 D5 dopamine receptor binding ; GO:0031752 | inferred from biological aspect of ancestor with PANTHER:PTN000026689 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000001047 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 heterotrimeric G-protein complex cycle ; GO:0031684 | inferred from sequence or structural similarity with SGD:S000001047 actin-mediated cell contraction ; GO:0070252 | inferred from genetic interaction with fog gastrulation ; GO:0007369 | traceable author statement regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 establishment or maintenance of cytoskeleton polarity involved in gastrulation ; GO:0003380 | inferred from mutant phenotype mesectoderm development ; GO:0048383 | inferred from mutant phenotype Rho protein signal transduction ; GO:0007266 | inferred from biological aspect of ancestor with PANTHER:PTN000026689 apical constriction involved in gastrulation ; GO:0003384 | inferred from genetic interaction with Gprk2 regulation of gastrulation ; GO:0010470 | inferred from mutant phenotype convergent extension involved in gastrulation ; GO:0060027 | inferred from mutant phenotype regulation of myosin II filament organization ; GO:0043519 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | non-traceable author statement heterotrimeric G-protein complex ; GO:0005834 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 brush border membrane ; GO:0031526 | inferred from biological aspect of ancestor with PANTHER:PTN000026689 heterotrimeric G-protein complex ; GO:0005834 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay heterotrimeric G-protein complex ; GO:0005834 | inferred from sequence or structural similarity with SGD:S000001047 "Cta, conc, mat(2)cta, CG40010, mat(2)fog, CG17678, cta, GNA12/13, Galpha[[12/13]]" "IPR000469:G-protein alpha subunit, group 12/13, IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17678 11-Aug-17 DroID_v2017_08 "Drer\gnai2a, Drer\LOC797518, Drer\gna13a, Drer\gnat2, Drer\gnai3, Drer\gnao1a, Drer\gnat1, Drer\gnai2b, Drer\gna12a, Drer\gnai1, Drer\gnao1b, Drer\gnaia, Drer\gna13b, Drer\gnav1" "Scer\GPA1, Scer\GPA2" Cele\gpa-12 "Xtro\gnai2, Xtro\gnai3, Xtro\gnat1, Xtro\gnat2, Xtro\gna13, Xtro\gnao1, Xtro\gnai1" "Mmus\Gnao1, Mmus\Gnat1, Mmus\Gna12, Mmus\Gnat3, Mmus\Gnaz, Mmus\Gnai1, Mmus\Gnai2, Mmus\Gnat2, Mmus\Gnai3, Mmus\Gna13" "Hsap\GNA12, Hsap\GNA13, Hsap\GNAT1, Hsap\GNAI1, Hsap\GNAZ, Hsap\GNAT2, Hsap\GNAT3, Hsap\GNAI2, Hsap\GNAO1, Hsap\GNAI3" " adult stage && oogenesis stage , embryonic stage " " nurse cell

, oocyte

, mesoderm

" "female sterile,wild-type,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,neuroanatomy defective,cell shape defective,partially lethal,lethal" "embryo,lateral,ventral furrow,amnioproctodeal invagination,embryonic/first instar larval cuticle,maternal effect,posterior endoderm,posterior midgut primordium,extended germ band embryo,cephalopharyngeal skeleton,egg chamber,nurse cell ring canal,embryonic epidermis,ventral,gonad,segmental nerve branch SNa of A1-7,anterior,posterior,embryo | embryonic stage 6" FBgn0267463 CR45813 - http://flybase.org/reports/FBgn0267463 non_protein_coding_gene - - - CR45813 - CR45813 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259447 EP-M68 - http://flybase.org/reports/FBgn0259447 gene - - - EP-M68 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0002433 l(3)KE142 lethal (3) KE142 http://flybase.org/reports/FBgn0002433 - gene - - - l(3)KE142 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033313 Cirl Calcium-independent receptor for alpha-latrotoxin http://flybase.org/reports/FBgn0033313 protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from electronic annotation with InterPro:IPR017981 carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR000922 latrotoxin receptor activity ; GO:0016524 | inferred from sequence or structural similarity cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity vesicle-mediated transport ; GO:0016192 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000203, InterPro:IPR017981 synaptic vesicle ; GO:0008021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "CG8639, dcirl, CIRL, BcDNA:GH07331, anon-WO0170980.8, anon-WO0170980.7, Cirl, dCirl" "IPR000203:GPS motif, IPR000922:D-galactoside/L-rhamnose binding SUEL lectin domain, IPR017981:GPCR, family 2-like, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032471:GAIN domain, N-terminal" CG8639 11-Aug-17 DroID_v2017_08 "Drer\adgre5b.2, Drer\adgrf6, Drer\si:dkeyp-46h3.8, Drer\si:ch211-226h8.11, Drer\crhr2, Drer\fbn2b, Drer\si:ch211-154a22.8, Drer\si:dkeyp-98a7.8, Drer\adgrl1a, Drer\zgc:171717, Drer\adgrd2, Drer\adgrg4a, Drer\si:dkeyp-98a7.4, Drer\si:dkeyp-98a7.7, Drer\LOC564755, Drer\LOC100535070, Drer\LOC100331909, Drer\adgre10, Drer\si:dkeyp-46h3.2, Drer\adgrf11, Drer\adgrg1, Drer\adgrl3.1, Drer\adgre9, Drer\adgre5b.3, Drer\LOC100535847, Drer\adgrg6, Drer\adgrf3a, Drer\adgrg2a, Drer\crhr1, Drer\adgre14, Drer\fbn2a, Drer\si:ch1073-75o15.4, Drer\LOC100331830, Drer\LOC100538279, Drer\LOC564145, Drer\adgrg11, Drer\LOC101884341, Drer\adgrg3, Drer\zgc:153499, Drer\adgrl2a, Drer\adgrl4, Drer\LOC101886975, Drer\si:dkeyp-98a7.5, Drer\eva1c, Drer\si:dkey-90l23.1, Drer\si:ch211-12h2.8, Drer\adgre15, Drer\LOC100537181, Drer\si:ch211-250e5.16, Drer\si:ch211-226h8.8, Drer\LOC100536657" - "Cele\lat-2, Cele\lat-1, Cele\fmi-1" "Xtro\adgrf3, Xtro\adgrv1, Xtro\adgrl1, Xtro\adgrf1, Xtro\eva1c, Xtro\adgre5, Xtro\adgrd1, Xtro\adgrg1" "Mmus\Crhr2, Mmus\Adgrd1, Mmus\Adgrf2, Mmus\Adgrg3, Mmus\Adgrl1, Mmus\Adgrg6, Mmus\Adgre4, Mmus\Adgrg2, Mmus\Adgre1, Mmus\Adgrg5, Mmus\Adgrf5, Mmus\Adgrl2, Mmus\Adgrl3, Mmus\Eva1c, Mmus\Adgrl4, Mmus\Crhr1, Mmus\Adgrf1, Mmus\Adgrf3, Mmus\Adgrg4, Mmus\Adgrg1, Mmus\Adgrf4, Mmus\Adgre5, Mmus\Adgrg7" "Hsap\ADGRL1, Hsap\ADGRF4, Hsap\ADGRE3, Hsap\EVA1C, Hsap\CRHR1, Hsap\ADGRL2, Hsap\ADGRF1, Hsap\ADGRE1, Hsap\ADGRG5, Hsap\ADGRG1, Hsap\ADGRE5, Hsap\ADGRL4, Hsap\CRHR2, Hsap\FBN3, Hsap\ADGRF2, Hsap\ADGRG2, Hsap\ADGRL3, Hsap\ADGRG3, Hsap\ADGRD2, Hsap\ADGRG4, Hsap\ADGRD1, Hsap\ADGRG6, Hsap\ADGRF3, Hsap\ADGRG7, Hsap\ADGRE2, Hsap\ADGRF5" "viable,fertile,lethal,partially lethal - majority die" FBgn0014926 anon-72ABj anon-72ABj http://flybase.org/reports/FBgn0014926 - gene - - - anon-72ABj - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011937 tRNA:Asn-GTT-1-2 transfer RNA:Asparagine-GTT 1-2 http://flybase.org/reports/FBgn0011937 "FBgn0003759, FBgn0053972, FBgn0060129" tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "CR33972, Asn7, Asn-tRNA-7, AE002769.trna11-AsnGTT, tRNA:N:GTT:AE002769-e, tRNA:asn5:42Ag, chr2R.trna2-AsnGTT, tRNA-Asn-GTT-1-2, tRNA:Asn-GTT-1-2, tRNA:N5:42Ag, AAC" - CR33972 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058399 CG40399 - http://flybase.org/reports/FBgn0058399 protein_coding_gene - - - CG40399 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22499 IE 2.82014913 -0.064975835 1.152973532 1.549008817 0.199241673 0.293157751 FBgn0260634 eIF4G2 eukaryotic translation initiation factor 4G2 http://flybase.org/reports/FBgn0260634 protein_coding_gene RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from genetic interaction with eIF4G1 spermatocyte division ; GO:0048137 | inferred from mutant phenotype inferred from genetic interaction with eIF4G1 spermatid differentiation ; GO:0048515 | inferred from mutant phenotype meiotic G2/MI transition ; GO:0008315 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern male germ-line cyst formation ; GO:0048136 | inferred from mutant phenotype - "eIF4G2, CG10192, ofs, nc32, ms(3)nc32, eIF4G-2" "IPR016024:Armadillo-type fold, IPR003890:MIF4G-like, type 3, IPR003891:Initiation factor eIF-4 gamma, MA3, IPR015943:WD40/YVTN repeat-like-containing domain" CG10192 11-Aug-17 DroID_v2017_08 "Drer\eif4g2a, Drer\eif4g3b, Drer\eif4g1b, Drer\eif4g2b, Drer\eif4g3a, Drer\eif4g1a" "Scer\YKU80, Scer\TIF4631, Scer\TIF4632" "Cele\ifg-1, Cele\abu-11" "Xtro\eif4g3, Xtro\eif4g2" "Mmus\Parp14, Mmus\Eif4g2, Mmus\Eif4g3, Mmus\Eif4g1" "Hsap\EIF4G1, Hsap\EIF4G2, Hsap\EIF4G3" FBgn0030798 CG13003 - http://flybase.org/reports/FBgn0030798 protein_coding_gene - - - CG13003 - CG13003 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0027570 Nep2 Neprilysin 2 http://flybase.org/reports/FBgn0027570 - protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from mutant phenotype metallopeptidase activity ; GO:0008237 | inferred from sequence model endopeptidase activity ; GO:0004175 | inferred from direct assay sperm competition ; GO:0046692 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model proteolysis ; GO:0006508 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "nep2, dNEP2, CG9761, BcDNA:GH07643, Nep2, DmNEP2, NEP2" "IPR018497:Peptidase M13, C-terminal domain, IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR030082:Neprilysin-21" CG9761 11-Aug-17 DroID_v2017_08 "Drer\phex, Drer\ece1, Drer\ece2b, Drer\mmel1" - "Cele\nep-12, Cele\nep-11, Cele\nep-2, Cele\nep-26, Cele\nep-1" "Xtro\ecel1, Xtro\ece1, Xtro\mmel1, Xtro\ece2" "Mmus\Mme, Mmus\Ecel1, Mmus\Kel, Mmus\Phex, Mmus\Mmel1, Mmus\Ece2, Mmus\Ece1" "Hsap\ECEL1, Hsap\MME, Hsap\MMEL1, Hsap\KEL, Hsap\ECE2, Hsap\ECE1, Hsap\PHEX" viable FBgn0017395 l(1)10Br lethal (1) 10Br http://flybase.org/reports/FBgn0017395 - gene - - - "HM12, l(1)10Br" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039112 SdhD "Succinate dehydrogenase, subunit D" http://flybase.org/reports/FBgn0039112 protein_coding_gene succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001000243 ubiquinone binding ; GO:0048039 | inferred from sequence or structural similarity with UniProtKB:A5GZW8 heme binding ; GO:0020037 | inferred from sequence or structural similarity with UniProtKB:A5GZW8 heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN001000243 succinate dehydrogenase activity ; GO:0000104 | inferred from sequence or structural similarity with UniProtKB:O14521 succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from sequence or structural similarity with UniProtKB:O14521 ubiquinone binding ; GO:0048039 | inferred from biological aspect of ancestor with PANTHER:PTN001000243 "tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN001000243 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:O14521 mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from biological aspect of ancestor with PANTHER:PTN001000243" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007992 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:A5GZW8 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from sequence or structural similarity with UniProtKB:A5GZW8 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from biological aspect of ancestor with PANTHER:PTN001000243 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from sequence or structural similarity with UniProtKB:O14521" "BEST:GH27735, SdhD, CG10219, DHSD" "IPR007992:Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS" CG10219 11-Aug-17 DroID_v2017_08 "Drer\sdhdb, Drer\sdhda" "Scer\TIM18, Scer\SHH4, Scer\SDH4" Cele\sdhd-1 Xtro\sdhd Mmus\Sdhd Hsap\SDHD viable FBgn0261501 CG42649 - http://flybase.org/reports/FBgn0261501 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42649 - CG42649 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000612 exi exigous http://flybase.org/reports/FBgn0000612 - gene - - - exi - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male fertile,good,female fertile,reduced,male,female,body color defective" "adult thorax,adult abdomen" FBgn0266389 CR45029 - http://flybase.org/reports/FBgn0266389 non_protein_coding_gene - - - CR45029 - CR45029 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250786 Chd1 Chromodomain-helicase-DNA-binding protein 1 http://flybase.org/reports/FBgn0250786 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002464 ATP-dependent helicase activity ; GO:0008026 | inferred from electronic annotation with InterPro:IPR002464 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR002464 helicase activity ; GO:0004386 | inferred from sequence or structural similarity chromatin binding ; GO:0003682 | inferred from direct assay helicase activity ; GO:0004386 | inferred from sequence or structural similarity with MGI:MGI:88393" "oogenesis ; GO:0048477 | inferred from mutant phenotype fertilization, exchange of chromosomal proteins ; GO:0035042 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype histone exchange ; GO:0043486 | inferred from mutant phenotype ATP-dependent chromatin remodeling ; GO:0043044 | inferred from mutant phenotype" polytene chromosome interband ; GO:0005705 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay "chd1, CHD1, Chd1, CG3733, CHD-1, dCHD1, DmCHD1, l(2)23Cd, CHD1,2" "IPR025260:Domain of unknown function DUF4208, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR001650:Helicase, C-terminal, IPR000953:Chromo/chromo shadow domain, IPR000330:SNF2-related, N-terminal domain, IPR016197:Chromo domain-like, IPR023779:Chromo domain, conserved site, IPR023780:Chromo domain" CG3733 11-Aug-17 DroID_v2017_08 "Drer\chd1, Drer\chd6, Drer\chd4a, Drer\zranb3, Drer\phf21ab, Drer\phf21aa, Drer\chd2, Drer\phf21b" Scer\CHD1 Cele\chd-1 "Xtro\chd4, Xtro\chd8, Xtro\chd1, Xtro\chd3, Xtro\chd2, Xtro\chd5" "Mmus\Chd4, Mmus\Phf21b, Mmus\Chd6, Mmus\Chd2, Mmus\Chd1, Mmus\Riok2, Mmus\Chd3, Mmus\Chd8" "Hsap\CHD6, Hsap\CHD1, Hsap\CHD2, Hsap\CHD3, Hsap\CHD8, Hsap\CHD4" embryonic stage&&adult stage FBgn0267067 CR45511 - http://flybase.org/reports/FBgn0267067 non_protein_coding_gene - - - CR45511 - CR45511 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260072 2L2526 - http://flybase.org/reports/FBgn0260072 gene - - - 2L2526 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0000103 aperB abnormal proboscis extension reflex B http://flybase.org/reports/FBgn0000103 - gene - proboscis extension reflex ; GO:0007637 | inferred from mutant phenotype - aperB - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,recessive,heat sensitive" FBgn0052407 CG32407 - http://flybase.org/reports/FBgn0052407 protein_coding_gene - - - "CG10727, BcDNA:AT29938, CG32407" "IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG32407 11-Aug-17 DroID_v2017_08 Drer\mospd2 "Scer\PDR17, Scer\CSR1, Scer\PDR16" "Cele\hpo-28, Cele\T03F7.7, Cele\ZC196.2" Xtro\mospd2 Mmus\Mospd2 Hsap\MOSPD2 viable FBgn0031305 Iris Iris http://flybase.org/reports/FBgn0031305 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern integral component of membrane ; GO:0016021 | inferred from reviewed computational analysis "CG4715, Iris, CG4715-env, Dm-cF" IPR022048:Envelope fusion protein-like CG4715 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0001244 hypoE hypoactive E http://flybase.org/reports/FBgn0001244 - gene - - - hypoE - - 11-Aug-17 DroID_v2017_08 - - - - - - "jumping defective,hypoactive,locomotor behavior defective" FBgn0010172 spno supernova http://flybase.org/reports/FBgn0010172 - gene - embryonic cleavage ; GO:0040016 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "fs(3)2-210, spno" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,non-rescuable maternal effect,recessive,maternal effect,lethal" "egg chamber,nurse cell,spermatocyte,spermatid" FBgn0263415 CR43461 - http://flybase.org/reports/FBgn0263415 non_protein_coding_gene - - - CR43461 - CR43461 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030007 alpha-PheRS "Phenylalanyl-tRNA synthetase, alpha-subunit" http://flybase.org/reports/FBgn0030007 protein_coding_gene "tRNA binding ; GO:0000049 | inferred from electronic annotation with InterPro:IPR002319 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002319, InterPro:IPR004529 phenylalanine-tRNA ligase activity ; GO:0004826 | inferred from direct assay aminoacyl-tRNA editing activity ; GO:0002161 | inferred from mutant phenotype phenylalanine-tRNA ligase activity ; GO:0004826 | traceable author statement" phenylalanyl-tRNA aminoacylation ; GO:0006432 | traceable author statement phenylalanyl-tRNA aminoacylation ; GO:0006432 | inferred from direct assay inferred from mutant phenotype cytoplasm ; GO:0005737 | traceable author statement phenylalanine-tRNA ligase complex ; GO:0009328 | inferred from biological aspect of ancestor with PANTHER:PTN000165935 "CG2263, alpha-PheRS" "IPR002319:Phenylalanyl-tRNA synthetase, IPR004529:Phenylalanyl-tRNA synthetase, class IIc, alpha subunit, IPR006195:Aminoacyl-tRNA synthetase, class II" CG2263 11-Aug-17 DroID_v2017_08 Drer\farsa Scer\FRS2 Cele\fars-1 Xtro\farsa Mmus\Farsa Hsap\FARSA lethal DRSC18224 I -0.688842262 1.51901377 -0.109299547 0.796783395 0.681994899 -0.599387696 FBgn0065436 l(2)SH1470 lethal (2) SH1470 http://flybase.org/reports/FBgn0065436 gene - - - "l(2)SH1470, l(2)SH2 1470" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020354 anon-2G8 anon-2G8 http://flybase.org/reports/FBgn0020354 - gene - - - "2G8, anon-2G8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025011 E(dpp)55A E(dpp)55A http://flybase.org/reports/FBgn0025011 - gene - - - E(dpp)55A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039170 CG13609 - http://flybase.org/reports/FBgn0039170 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13609 "IPR021394:Mediator complex, subunit Med25, PTOV activation and synapsin 2" CG13609 11-Aug-17 DroID_v2017_08 Drer\med25 - - Xtro\med25 "Mmus\Ptov1, Mmus\Med25" "Hsap\MED25, Hsap\PTOV1" viable FBgn0037999 CG4860 - http://flybase.org/reports/FBgn0037999 protein_coding_gene flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786 acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from sequence or structural similarity with HGNC:30211 fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:30211 - "CG4860, Dmel\CG4860" "IPR006089:Acyl-CoA dehydrogenase, conserved site, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal" CG4860 11-Aug-17 DroID_v2017_08 "Drer\acad9, Drer\acadvl, Drer\acads, Drer\acadm, Drer\acad8, Drer\zgc:85777" - "Cele\acdh-4, Cele\acdh-9, Cele\acdh-1, Cele\acdh-3, Cele\acdh-7, Cele\acdh-8, Cele\acdh-2" "Xtro\ivd, Xtro\acad8, Xtro\acadm, Xtro\MGC147631, Xtro\acads, Xtro\acadsb, Xtro\acad9" "Mmus\Ivd, Mmus\Acad9, Mmus\Acadvl, Mmus\Acad8, Mmus\Acadsb, Mmus\Acads, Mmus\Acadm" "Hsap\ACAD9, Hsap\ACADS, Hsap\ACADM, Hsap\IVD, Hsap\ACADSB, Hsap\ACADVL, Hsap\ACAD8" viable FBgn0036502 CG7841 - http://flybase.org/reports/FBgn0036502 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7841 IPR029428:Mapk-regulated corepressor-interacting protein CG7841 11-Aug-17 DroID_v2017_08 "Drer\fam195b, Drer\si:dkey-44g23.5" - - "Xtro\fam195b, Xtro\fam195a" "Mmus\Fam195b, Mmus\Fam195a" "Hsap\MCRIP1, Hsap\MCRIP2" FBgn0026626 pel perle http://flybase.org/reports/FBgn0026626 - gene molecular_function ; GO:0003674 | no biological data available central nervous system development ; GO:0007417 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available pel - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic/larval central nervous system,commissure,midline glial cell,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron" FBgn0000297 Cg19-20 Cg19-20 http://flybase.net/reports/FBgn0000297.html FBgn0000298 gene 0005587=collagen type IV trimer "Cg19EF, Collagen 19EF, Cg20AB, DCg2, Collagen 20AB" 11-Aug-17 DroID_v2017_08 FBgn0051849 CG31849 - http://flybase.org/reports/FBgn0051849 protein_coding_gene "beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity ; GO:0003830 | inferred from electronic annotation with InterPro:IPR006813" protein N-linked glycosylation ; GO:0006487 | inferred from electronic annotation with InterPro:IPR006813 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006813 "BcDNA:LD34806, CG31849, dMGAT3" "IPR006813:Glycosyl transferase, family 17" CG31849 11-Aug-17 DroID_v2017_08 Drer\mgat3a - "Cele\K12H6.9, Cele\Y111B2A.21, Cele\Y53F4B.16" Xtro\mgat3 Mmus\Mgat3 Hsap\MGAT3 "viable,body color defective" mesothoracic tergum FBgn0069118 mus212 mutagen-sensitive 212 http://flybase.org/reports/FBgn0069118 gene - - - mus212 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive,female sterile,recessive" FBgn0262521 l(3)psg3 lethal (3) persistent salivary gland 3 http://flybase.org/reports/FBgn0262521 gene - regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype - "l(3)psg3, psg3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during P-stage" embryonic/larval salivary gland FBgn0039467 CG14253 - http://flybase.org/reports/FBgn0039467 protein_coding_gene - - - CG14253 - CG14253 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260372 GSd485 - http://flybase.org/reports/FBgn0260372 gene - - - GSd485 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0086037 snoRNA:Me28S-A2958 - http://flybase.org/reports/FBgn0086037 snoRNA_gene - - - "snoRNA:Me28S-A2958, Me28S-Am2958, CR34666" - CR34666 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046663 anon-38C.36 anon-38C.36 http://flybase.org/reports/FBgn0046663 gene - - - "38C.36, anon-38C.36" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036509 CG7739 - http://flybase.org/reports/FBgn0036509 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7739 IPR024881:T-cell immunomodulatory protein CG7739 11-Aug-17 DroID_v2017_08 Drer\itfg1 - Cele\lnkn-1 Xtro\itfg1 Mmus\Itfg1 Hsap\ITFG1 "viable,fertile" FBgn0028244 l(3)S000625a lethal (3) S000625a http://flybase.org/reports/FBgn0028244 gene - - - "0006/25, l(3)S000625, l(3)S000625a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262788 CG43169 - http://flybase.org/reports/FBgn0262788 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43169, MB8.chr3L.pasa.50" - CG43169 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028397 Tob Tob http://flybase.org/reports/FBgn0028397 protein_coding_gene transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN000426292 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VSR3 signaling ; GO:0023052 | inferred from biological aspect of ancestor with PANTHER:PTN000426292 regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000426292 protein oligomerization ; GO:0051259 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000426292 synaptic membrane ; GO:0097060 | inferred from direct assay cell body ; GO:0044297 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000426292 "CG9214, Tob" "IPR002087:Anti-proliferative protein, IPR015676:Tob1/2" CG9214 11-Aug-17 DroID_v2017_08 "Drer\btg2, Drer\btg4, Drer\tob1a, Drer\btg3, Drer\si:dkey-79d12.5, Drer\tob1b, Drer\btg1, Drer\si:dkey-42i9.4" - "Cele\T09B4.6, Cele\fog-3" "Xtro\btg3, Xtro\MGC75753, Xtro\btg4, Xtro\btg5, Xtro\LOC733731, Xtro\btg1, Xtro\tob1, Xtro\MGC76328, Xtro\btg2" "Mmus\Btg3, Mmus\Btg2, Mmus\Btg1, Mmus\Btg4, Mmus\Btg1-ps2, Mmus\Tob2, Mmus\Tob1, Mmus\Btg1-ps1" "Hsap\BTG2, Hsap\BTG1, Hsap\BTG3, Hsap\BTG4, Hsap\TOB2, Hsap\TOB1" "lethal,recessive,viable" embryonic/larval hemocyte | third instar larval stage FBgn0266038 CR44803 - http://flybase.org/reports/FBgn0266038 non_protein_coding_gene - - - "CR44803, lincRNA.223" - CR44803 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264823 CR44031 - http://flybase.org/reports/FBgn0264823 non_protein_coding_gene - - - CR44031 - CR44031 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066352 l(3)99DEc lethal (3) 99DEc http://flybase.org/reports/FBgn0066352 gene - - - l(3)99DEc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005671 Vha55 Vacuolar H[+]-ATPase 55kD subunit http://flybase.org/reports/FBgn0005671 "FBgn0002345, FBgn0011789" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from direct assay inferred from genetic interaction with SGD:S000000331" ATP metabolic process ; GO:0046034 | inferred from electronic annotation with InterPro:IPR004100 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from genetic interaction with SGD:S000000331 vacuolar acidification ; GO:0007035 | inferred from direct assay "plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype early endosome ; GO:0005769 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD:S000000331 brush border ; GO:0005903 | inferred from direct assay" "vha55, SzA, CG17369, l(3)j2E9, l(3)87Ca, VAT-2, 1208/13, l(3)SzA, Vha55, ATP6V1B1, V-ATPase" "IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005723:ATPase, V1 complex, subunit B, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR024034:ATPase, F1/V1 complex, beta/alpha subunit, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022879:V-type ATP synthase regulatory subunit B/beta" CG17369 11-Aug-17 DroID_v2017_08 "Drer\atp6v1ba, Drer\atp6v1b2" Scer\VMA2 "Cele\vha-12, Cele\spe-5" "Xtro\atp6v1b1, Xtro\atp6v1b2" "Mmus\Atp6v1b2, Mmus\Atp6v1b1" "Hsap\ATP6V1B2, Hsap\ATP6V1B1" "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,size defective,decreased cell number,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "Malpighian tubule,eye disc,somatic clone,multivesicular body | larval stage | somatic clone" FBgn0023152 Su(mg)2-7 Suppressor of modifier of gypsy 2-7 http://flybase.org/reports/FBgn0023152 - gene - - - Su(mg)2-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000551 Edg78E Ecdysone-dependent gene 78E http://flybase.org/reports/FBgn0000551 "FBtr0078408, FBpp0078062" protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of pupal chitin-based cuticle ; GO:0008011 | traceable author statement structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Edg78e, EDG78E, DMLCP78, Edg78, EDG78, EDG-78, CG7673, Edg78E, DmelEdg78E" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG7673 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\math-34, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - prepupal stage epidermis

viable FBgn0016950 tilG touch insensitive larva G http://flybase.org/reports/FBgn0016950 - gene - - - "line 376, tilG" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0002674 mat(2)syn-B maternal effect syncytial blastoderm arrest B http://flybase.org/reports/FBgn0002674 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "syn-Hi10, mat(2)synHi10, mat(2)syn-B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0030455 CG4318 - http://flybase.org/reports/FBgn0030455 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG4318 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG4318 11-Aug-17 DroID_v2017_08 "Drer\LOC101885937, Drer\zgc:193790, Drer\zgc:174224" Scer\AZF1 "Cele\F26A10.2, Cele\C46E10.9" Xtro\e4f1 "Mmus\Klf13, Mmus\Klf9, Mmus\Klf14, Mmus\Klf16" Hsap\ZNF480 viable FBgn0250908 beat-VII beat-VII http://flybase.org/reports/FBgn0250908 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic - "beat-VII, CG14249, beat VII, CG14248, CG42242, Beat-VII" "IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013783:Immunoglobulin-like fold" CG42242 11-Aug-17 DroID_v2017_08 - - - - - Hsap\CADM2 FBgn0015253 M(2)105 M(2)105 http://flybase.org/reports/FBgn0015253 - gene - - - M(2)105 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,Minute" FBgn0051612 CG31612 - http://flybase.org/reports/FBgn0051612 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 lateral inhibition ; GO:0046331 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay "CG11632, CG11631, CG31612" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG31612 11-Aug-17 DroID_v2017_08 "Drer\znf644a, Drer\znf407, Drer\si:dkey-208k4.2, Drer\znf644b, Drer\znf142" Scer\PZF1 "Cele\klu-1, Cele\F21A9.2, Cele\pzf-1, Cele\mep-1, Cele\unc-98, Cele\Y56A3A.28, Cele\eor-1" Xtro\znf644 "Mmus\Zfp644, Mmus\Wiz, Mmus\Zfp407, Mmus\Zfp788" "Hsap\ZNF407, Hsap\ZNF850, Hsap\ZNF836, Hsap\ZNF607, Hsap\ZFP28, Hsap\ZNF709, Hsap\ZNF14, Hsap\ZNF614, Hsap\ZBTB24, Hsap\ZNF644, Hsap\WIZ, Hsap\ZNF280C, Hsap\ZNF780A" "viable,visible" chaeta DRSC03697 K -0.711753797 0.715122099 -0.65856561 0.284256276 -1.435859788 1.553365809 FBgn0266973 CR45424 - http://flybase.org/reports/FBgn0266973 non_protein_coding_gene - - - CR45424 - CR45424 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266225 CR44920 - http://flybase.org/reports/FBgn0266225 non_protein_coding_gene - - - CR44920 - CR44920 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035657 alphaKap4 alpha Karyopherin-4 http://flybase.org/reports/FBgn0035657 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 proteasome assembly ; GO:0043248 | inferred from electronic annotation with InterPro:IPR019538 NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 "g7295403, CG11040, CG10478, alphaKap4" "IPR000225:Armadillo, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024931:Importin subunit alpha, IPR019538:26S proteasome non-ATPase regulatory subunit 5" CG10478 11-Aug-17 DroID_v2017_08 "Drer\kpna4, Drer\spag6, Drer\kpna3, Drer\kpna1, Drer\kpna7, Drer\kpna6, Drer\kpna5" Scer\SRP1 Cele\ima-3 "Xtro\kpna7, Xtro\armc3, Xtro\kpna6, Xtro\kpna2, Xtro\kpna4, Xtro\kpna3, Xtro\kpna1, Xtro\spag6" "Mmus\Kpna7, Mmus\Spag6, Mmus\Kpna2, Mmus\Spag6l, Mmus\Kpna3, Mmus\Kpna6, Mmus\Kpna1, Mmus\Kpna4" "Hsap\KPNA1, Hsap\SPAG6, Hsap\KPNA2, Hsap\KPNA3, Hsap\KPNA5, Hsap\KPNA7, Hsap\KPNA6, Hsap\KPNA4" viable FBgn0030158 CG9686 - http://flybase.org/reports/FBgn0030158 protein_coding_gene - - - "CT6802, anon-EST:Posey3, BcDNA:RH74092, CG9686" - CG9686 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC18439 E 1.032549265 -0.838006684 1.777192874 -0.943145617 -0.345358448 0.537755849 FBgn0264437 CR43855 - http://flybase.org/reports/FBgn0264437 non_protein_coding_gene - - - CR43855 - CR43855 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261588 pdm3 pou domain motif 3 http://flybase.org/reports/FBgn0261588 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000327 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR009057, InterPro:IPR010982, InterPro:IPR013847" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000327 axon guidance ; GO:0007411 | inferred from mutant phenotype axon target recognition ; GO:0007412 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype" - "pdm3, CG42698, CG11641, BcDNA:AT16994, CG14755, Pdm3" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR000327:POU-specific domain, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR010982:Lambda repressor-like, DNA-binding domain, IPR013847:POU domain" CG42698 11-Aug-17 DroID_v2017_08 "Drer\pou6f2, Drer\pou2f3, Drer\pou3f3a, Drer\pou3f2b, Drer\pou6f1, Drer\pou5f3, Drer\pou2f2a, Drer\pou3f2a, Drer\pou3f3b, Drer\pou2f1a, Drer\pou1f1, Drer\pou3f1" - Cele\ceh-6 "Xtro\pou6f2, Xtro\pou2f3, Xtro\pou5f3.1, Xtro\pou3f1, Xtro\pou5f3.2, Xtro\pou6f1, Xtro\pou3f3, Xtro\pou3f4, Xtro\pou1f1" "Mmus\Pou3f3, Mmus\Pou2f1, Mmus\Pou5f2, Mmus\Pou3f2, Mmus\Pou3f1, Mmus\Pou3f4, Mmus\Pou6f2, Mmus\Pou5f1, Mmus\Pou6f1, Mmus\Gm9376, Mmus\Pou2f2, Mmus\Pou2f3, Mmus\Pou1f1" "Hsap\POU3F3, Hsap\POU3F1, Hsap\POU5F1B, Hsap\POU2F1, Hsap\POU3F2, Hsap\POU2F3, Hsap\POU6F1, Hsap\POU2F2, Hsap\POU5F1, Hsap\POU5F2, Hsap\POU3F4, Hsap\POU6F2, Hsap\POU1F1" FBgn0027983 l(3)S134303 lethal (3) S134303 http://flybase.org/reports/FBgn0027983 gene - - - "1343/03, l(3)S134303" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027179 l(2)60A-O lethal (2) 60A-O http://flybase.org/reports/FBgn0027179 - gene - - - l(2)60A-O - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016894 l(3)64Cd lethal (3) 64Cd http://flybase.org/reports/FBgn0016894 - gene - - - l(3)64Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060713 l(3)S070106b lethal (3) S070106b http://flybase.org/reports/FBgn0060713 gene - - - "0701/06, l(3)S070106b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033733 CG8834 - http://flybase.org/reports/FBgn0033733 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - "CG8834, mdcds_23070" "IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site, IPR025110:AMP-binding enzyme C-terminal domain" CG8834 11-Aug-17 DroID_v2017_08 "Drer\acsf3, Drer\acsbg1" "Scer\FAT1, Scer\PCS60" "Cele\acs-9, Cele\acs-14, Cele\C25G6.3, Cele\acs-10, Cele\C32E8.6, Cele\acs-7, Cele\acs-6, Cele\mec-18, Cele\acs-22" Xtro\acsf3 "Mmus\Acsf3, Mmus\Acsbg1, Mmus\Slc27a6" "Hsap\ACSBG1, Hsap\SLC27A6, Hsap\ACSF3" viable FBgn0035453 CG10357 - http://flybase.org/reports/FBgn0035453 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available CG10357 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG10357 11-Aug-17 DroID_v2017_08 "Drer\pla1a, Drer\LOC101884800, Drer\LOC100331214, Drer\lipg, Drer\lipib, Drer\lpl, Drer\lipca, Drer\lipia" - - "Xtro\lpl, Xtro\lipg" "Mmus\Lipg, Mmus\Pnliprp2, Mmus\Pnliprp1, Mmus\Pla1a, Mmus\Lipi, Mmus\Pnlip, Mmus\Lpl, Mmus\Liph, Mmus\Lipc" "Hsap\PNLIPRP3, Hsap\PNLIPRP1, Hsap\LPL, Hsap\LIPC, Hsap\PLA1A, Hsap\LIPI, Hsap\PNLIPRP2, Hsap\PNLIP, Hsap\LIPH, Hsap\LIPG" viable FBgn0000191 bkl buckledlike http://flybase.org/reports/FBgn0000191 - gene - - - bkl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile" "wing,wing vein,eye" FBgn0035452 CG10359 - http://flybase.org/reports/FBgn0035452 protein_coding_gene chitin binding ; GO:0008061 | inferred from sequence or structural similarity with HGNC:25922 G-protein coupled receptor binding ; GO:0001664 | inferred from sequence or structural similarity with HGNC:3623 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with HGNC:3623 membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:25922 "CG10359, AAF47782, FBpp0072995" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1" CG10359 11-Aug-17 DroID_v2017_08 "Drer\zgc:171687, Drer\zgc:194887, Drer\si:ch1073-110a20.1, Drer\zgc:173915, Drer\fga, Drer\si:dkeyp-51b7.3, Drer\si:zfos-2330d3.8, Drer\angptl7, Drer\tnxba, Drer\tnr, Drer\angpt4, Drer\LOC555374, Drer\fgl2a, Drer\angptl5, Drer\fgg, Drer\si:ch211-287a12.9, Drer\fibcd1, Drer\fgb, Drer\angptl3, Drer\angptl4, Drer\tnc, Drer\si:ch211-157b11.8, Drer\si:zfos-2330d3.6, Drer\mfap4, Drer\si:ch1073-110a20.3, Drer\LOC100007488, Drer\tnw, Drer\fgl2b, Drer\angpt1, Drer\si:ch1073-110a20.2, Drer\si:zfos-2330d3.1, Drer\si:ch211-203k16.3, Drer\angptl2a, Drer\si:zfos-2330d3.3, Drer\zmp:0000000846, Drer\angpt2a, Drer\angptl6, Drer\wu:fj11g02, Drer\fgl1, Drer\angptl2b, Drer\angptl1a, Drer\angpt2b" - "Cele\W05B2.2, Cele\C08G9.2, Cele\Y69H2.3, Cele\Y43C5A.2, Cele\Y69H2.10, Cele\ensh-1, Cele\T15B7.1, Cele\Y26D4A.12, Cele\K10D3.4, Cele\ZC504.1" "Xtro\angptl3, Xtro\fcn3, Xtro\fgb, Xtro\fcn2, Xtro\LOC100491105, Xtro\fcn1, Xtro\LOC100497330, Xtro\tnc, Xtro\tnxb, Xtro\fgl2, Xtro\tnn, Xtro\mfap4, Xtro\angpt4, Xtro\angptl2, Xtro\tnr, Xtro\angptl5, Xtro\fibcd1, Xtro\angptl4, Xtro\fgl1, Xtro\fgg, Xtro\LOC100488177, Xtro\angpt1, Xtro\fga" "Mmus\Angptl6, Mmus\Fga, Mmus\Tnn, Mmus\Fgg, Mmus\Angptl7, Mmus\Angpt2, Mmus\Angptl3, Mmus\Angptl1, Mmus\Angpt4, Mmus\Fgl1, Mmus\Angptl2, Mmus\Fgb, Mmus\Tnr, Mmus\Fcnb, Mmus\Tnxb, Mmus\Angptl4, Mmus\Tnc, Mmus\Fibcd1, Mmus\Fgl2, Mmus\Mfap4, Mmus\Angpt1, Mmus\Fcna" "Hsap\FGL1, Hsap\TNC, Hsap\ANGPTL4, Hsap\MFAP4, Hsap\FGA, Hsap\TNXB, Hsap\ANGPTL1, Hsap\ANGPTL6, Hsap\ANGPT1, Hsap\FGL2, Hsap\FCN2, Hsap\FCN1, Hsap\FCN3, Hsap\ANGPTL7, Hsap\ANGPT2, Hsap\ANGPT4, Hsap\TNN, Hsap\FGG, Hsap\ANGPTL5, Hsap\ANGPTL2, Hsap\TNR, Hsap\FIBCD1, Hsap\ANGPTL3, Hsap\FGB" viable FBgn0039961 CG17679 - http://flybase.org/reports/FBgn0039961 protein_coding_gene - - - CG17679 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014326 l(3)ry6 lethal (3) ry6 http://flybase.org/reports/FBgn0014326 - gene - - - l(3)ry6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037299 Vps37B Vacuolar protein sorting 37B http://flybase.org/reports/FBgn0037299 protein_coding_gene molecular_function ; GO:0003674 | no biological data available endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred by curator from GO:0000813 ESCRT I complex ; GO:0000813 | inferred from sequence or structural similarity with SGD:S000004109 ESCRT I complex ; GO:0000813 | inferred from direct assay "vps37B, CG1115, DmVPS37, Vps37, Vps37B" "IPR009851:Modifier of rudimentary, Modr" CG1115 11-Aug-17 DroID_v2017_08 "Drer\vps37b, Drer\vps37c, Drer\zgc:66474, Drer\zgc:101016, Drer\vps37a, Drer\si:ch211-284f22.3, Drer\zgc:114173" Scer\SRN2 "Cele\vps-37, Cele\CD4.5" "Xtro\c9orf85, Xtro\vps37a, Xtro\vps37b" "Mmus\1110059E24Rik, Mmus\Vps37c, Mmus\Vps37b, Mmus\Vps37a, Mmus\Vps37d" "Hsap\VPS37C, Hsap\VPS37B, Hsap\C9orf85, Hsap\VPS37A, Hsap\VPS37D" "viable,fertile" FBgn0052173 tRNA:Pro-CGG-2-2 transfer RNA:Proline-CGG 2-2 http://flybase.org/reports/FBgn0052173 tRNA_gene CCG codon-amino acid adaptor activity ; GO:0033424 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033424 cytosol ; GO:0005829 | inferred by curator from GO:0033424 "AE002602.trna1-ProCGG, tRNA:P:CGG:AE002602-a, CR32173, chr3L.trna35-ProCGG, tRNA-Pro-CGG-2-2, tRNA:Pro-CGG-2-2, tRNA:CR32173, CCG" - CR32173 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0052182 CG32182 - http://flybase.org/reports/FBgn0052182 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32182 "IPR032675:Leucine-rich repeat domain, L domain-like" CG32182 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0083247 EB3 EB3 http://flybase.org/reports/FBgn0083247 gene - - - EB3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028113 l(3)S065103 lethal (3) S065103 http://flybase.org/reports/FBgn0028113 gene - - - "0651/03, l(3)S065103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002315 l(3)85Af lethal (3) 85Af http://flybase.org/reports/FBgn0002315 - gene - - - "L6, l(3)85Af" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065522 l(2)SH1125 lethal (2) SH1125 http://flybase.org/reports/FBgn0065522 gene - - - "l(2)SH1125, l(2)SH2 1125" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020607 anon-12Dc anon-12Dc http://flybase.org/reports/FBgn0020607 - gene - - - "D2, anon-12Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020765 Acp65Aa Adult cuticle protein 65Aa http://flybase.org/reports/FBgn0020765 FBgn0062922 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Acp65A, DMACP65A, DCP5, CG10297, BcDNA:RH61147, Acp65Aa, ACP65A, DmelAcp65Aa" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG10297 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\F44F1.4, Cele\math-34" - "Mmus\H2-K1, Mmus\2410137M14Rik" - pupal stage | 50-80 hr viable FBgn0065936 l(2)SH0124 lethal (2) SH0124 http://flybase.org/reports/FBgn0065936 gene - - - "l(2)SH0124, l(2)SH2 0124" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084020 CG41458 - http://flybase.org/reports/FBgn0084020 protein_coding_gene - - - CG41458 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039869 CG1890 - http://flybase.org/reports/FBgn0039869 protein_coding_gene beta-tubulin binding ; GO:0048487 | inferred from electronic annotation with InterPro:IPR004226 tubulin complex assembly ; GO:0007021 | inferred from electronic annotation with InterPro:IPR004226 post-chaperonin tubulin folding pathway ; GO:0007023 | inferred from electronic annotation with InterPro:IPR004226 - CG1890 IPR004226:Tubulin binding cofactor A CG1890 11-Aug-17 DroID_v2017_08 Drer\tbca Scer\RBL2 Cele\tbca-1 Xtro\tbca Mmus\Tbca Hsap\TBCA "viable,fertile" DRSC15395 I -0.449117659 -1.52719604 -0.093396222 0.047877916 -0.092281287 -0.163845916 FBgn0005474 l(1)ts996 lethal (1) ts996 http://flybase.org/reports/FBgn0005474 - gene - - - l(1)ts996 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0283430 CR46273 - http://flybase.org/reports/FBgn0283430 pseudogene_attribute - - - CR46273 - CR46273 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267420 CR45773 - http://flybase.org/reports/FBgn0267420 pseudogene_attribute - - - "CR45773, Mst77Y" - CR45773 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086347 Myo31DF Myosin 31DF http://flybase.org/reports/FBgn0086347 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609 motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR010926 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" determination of left/right symmetry ; GO:0007368 | inferred from mutant phenotype determination of digestive tract left/right asymmetry ; GO:0071907 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype "myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR010926 myosin complex ; GO:0016459 | inferred from sequence or structural similarity cell cortex ; GO:0005938 | inferred from direct assay" "Myo31DF, CG7438, Myo-IA, Dm IA, DmIA, MYOIA, Myo1A, IA, DroMIA, souther, MyoID, MyoIA, myoID, Mhc1, myo31DF, Myo1D" "IPR010926:Class I myosin tail homology domain, IPR001609:Myosin head, motor domain, IPR000048:IQ motif, EF-hand binding site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7438 11-Aug-17 DroID_v2017_08 "Drer\myo1hb, Drer\myo1f, Drer\si:ch211-94l19.4, Drer\myo1ea, Drer\si:dkeyp-92c9.3, Drer\myo1eb, Drer\myo1b, Drer\myo1ca, Drer\myo1cb, Drer\myo1ha" "Scer\MYO5, Scer\MYO3" "Cele\hum-1, Cele\hum-6, Cele\hum-5" "Xtro\myo1e.1, Xtro\myo1a, Xtro\myo1f, Xtro\myo1h, Xtro\myo1e.2, Xtro\myo1c, Xtro\myo1d" "Mmus\Myo1c, Mmus\Myo1d, Mmus\Myo1g, Mmus\Myo1h, Mmus\Myo1e, Mmus\Myo1b, Mmus\Myo1a, Mmus\Myo1f" "Hsap\MYO1C, Hsap\MYO1E, Hsap\MYO1G, Hsap\MYO1F, Hsap\MYO1B, Hsap\MYO1A, Hsap\MYO1D, Hsap\MYO1H" embryonic stage -- adult stage " embryonic stage -- adult stage , embryonic stage | late " " embryonic/larval hindgut

, embryonic/larval proventriculus

, gastric caecum

, embryonic/larval digestive system

, embryonic/larval midgut

" FBgn0010504 kermit kermit http://flybase.org/reports/FBgn0010504 "FBgn0026587, FBgn0033270" protein_coding_gene G-protein alpha-subunit binding ; GO:0001965 | inferred from physical interaction with Gαo determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | NOT inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype vesicle ; GO:0031982 | colocalizes_with inferred from direct assay "l(2)02045, CG11546, LD04728, BEST:LD04728, kermit, dGIPC, dKermit" "IPR001478:PDZ domain, IPR017379:PDZ domain-containing protein GIPC1/2/3" CG11546 11-Aug-17 DroID_v2017_08 "Drer\gipc3, Drer\gipc1, Drer\oxct1b, Drer\gipc2" - "Cele\gipc-1, Cele\gipc-2, Cele\C05C10.3" "Xtro\gipc2, Xtro\gipc1, Xtro\gipc3" "Mmus\Oxct1, Mmus\Gipc1, Mmus\Oxct2a, Mmus\Oxct2b, Mmus\Gipc3, Mmus\Gipc2" "Hsap\GIPC3, Hsap\GIPC2, Hsap\OXCT2, Hsap\GIPC1" "planar polarity defective,visible,wild-type,locomotor behavior defective,short lived,heat stress response defective,lethal,recessive,partially lethal - majority die,viable,dominant" "wing hair,supernumerary,trichome,mesothoracic tergum,dopaminergic neuron,wing" FBgn0022982 retx retinal exchanger http://flybase.org/reports/FBgn0022982 - gene - - - retx - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027965 l(3)S145110 lethal (3) S145110 http://flybase.org/reports/FBgn0027965 gene - - - "1451/10, l(3)S145110, l(3)s145110" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0028089 l(3)S083705 lethal (3) S083705 http://flybase.org/reports/FBgn0028089 gene - - - "0837/05, l(3)S083705" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0037174 CG14457 - http://flybase.org/reports/FBgn0037174 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CG18618, BcDNA:LP08817, CG14457" IPR010562:Haemolymph juvenile hormone binding CG14457 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263763 CG43680 - http://flybase.org/reports/FBgn0263763 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43680 - CG43680 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032330 Samuel SAM-motif ubiquitously expressed punctatedly localized protein http://flybase.org/reports/FBgn0032330 protein_coding_gene - regulation of growth ; GO:0040008 | inferred from mutant phenotype regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype - "Moses, CG31868, CG14917, CG14918, CG12291, Samuel, moses, 78BP, mdcds_1002" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG31868 11-Aug-17 DroID_v2017_08 "Drer\phc1, Drer\phc3, Drer\si:ch211-230g15.5, Drer\samd11, Drer\phc2a, Drer\samd7, Drer\sfmbt2, Drer\phc2b, Drer\sfmbt1, Drer\scml4" - "Cele\sor-3, Cele\K02F6.7" Xtro\samd7 "Mmus\Samd7, Mmus\Sfmbt2, Mmus\Scml4, Mmus\Sfmbt1, Mmus\Phc1, Mmus\Phc3, Mmus\Phc2, Mmus\Samd11" "Hsap\PHC2, Hsap\SFMBT2, Hsap\SFMBT1, Hsap\PHC1, Hsap\SCML4, Hsap\SAMD7, Hsap\SCML1, Hsap\SAMD11, Hsap\PHC3" "viable,fertile,lethal - all die before end of P-stage,some die during P-stage,lethal,hyperplasia,developmental rate defective" "imaginal disc,embryonic/larval brain" FBgn0086042 snoRNA:Me28S-G980 - http://flybase.org/reports/FBgn0086042 snoRNA_gene - - - "snoRNA:Me28S-G980, Me28S-Gm980, Me28S-G980, CR34671" - CR34671 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028057 l(3)S094204 lethal (3) S094204 http://flybase.org/reports/FBgn0028057 gene - - - "0942/04, l(3)S094204" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084437 l(3)76BDj l(3)76BDj http://flybase.org/reports/FBgn0084437 gene - - - l(3)76BDj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036688 Fit2 Fermitin 2 http://flybase.org/reports/FBgn0036688 protein_coding_gene - cardiac muscle tissue development ; GO:0048738 | inferred from genetic interaction with Fit1 - "CG7729, Fit2, Cg7729, Fit 2" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019748:FERM central domain, IPR019749:Band 4.1 domain" CG7729 11-Aug-17 DroID_v2017_08 "Drer\fermt2, Drer\fermt3b, Drer\fermt1, Drer\im:7154036" - Cele\unc-112 "Xtro\fermt2, Xtro\fermt1, Xtro\fermt3" "Mmus\Fermt1, Mmus\Fermt3, Mmus\Fermt2" "Hsap\FERMT3, Hsap\FERMT2, Hsap\FERMT1" "viable,fertile" FBgn0039156 CG6178 - http://flybase.org/reports/FBgn0039156 protein_coding_gene long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from direct assay fatty-acyl-CoA synthase activity ; GO:0004321 | inferred from direct assay luciferin monooxygenase activity ; GO:0045289 | NOT inferred from direct assay fatty-acyl-CoA biosynthetic process ; GO:0046949 | inferred from direct assay acyl-CoA metabolic process ; GO:0006637 | inferred from direct assay long-chain fatty acid metabolic process ; GO:0001676 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence model CG6178 "IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site" CG6178 11-Aug-17 DroID_v2017_08 "Drer\acsf2, Drer\acsbg1, Drer\acsf3" Scer\PCS60 "Cele\acs-21, Cele\acs-7, Cele\acs-12, Cele\C25G6.3, Cele\acs-10, Cele\mec-18, Cele\acs-1, Cele\acs-6, Cele\acs-9, Cele\acs-14" Xtro\acsf3 "Mmus\Acsm3, Mmus\Acsf3, Mmus\Acsf2, Mmus\Acsbg1" "Hsap\ACSF3, Hsap\ACSBG1, Hsap\ACSM3, Hsap\ACSF2" "viable,fertile" FBgn0063498 GstE2 Glutathione S transferase E2 http://flybase.org/reports/FBgn0063498 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTE2, CG17523, GstE2, GSTE2, gste2" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17523 11-Aug-17 DroID_v2017_08 "Drer\gstr, Drer\gstt1b, Drer\mars, Drer\gstt1a, Drer\eef1e1, Drer\gstt2, Drer\eef1g, Drer\vars" "Scer\GTT2, Scer\CAM1, Scer\YGR201C, Scer\TEF4, Scer\URE2, Scer\GTT1" "Cele\gst-21, Cele\gst-34, Cele\gst-29" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Mars, Mmus\Vars, Mmus\Gstt3, Mmus\Eef1e1, Mmus\Gstt2, Mmus\Gstt4, Mmus\Eef1g, Mmus\Gstt1" "Hsap\GSTT1, Hsap\GSTT2, Hsap\EEF1G, Hsap\VARS, Hsap\EEF1E1, Hsap\MARS, Hsap\GSTT2B" viable FBgn0037930 CG14715 - http://flybase.org/reports/FBgn0037930 protein_coding_gene FK506 binding ; GO:0005528 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 endomembrane system ; GO:0012505 | inferred from direct assay "BcDNA:RH50927, BcDNA:GM09283, CG14715" "IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type" CG14715 11-Aug-17 DroID_v2017_08 "Drer\fkbp11, Drer\si:ch73-199g24.2, Drer\fkbp10b, Drer\fkbp10a, Drer\fkbp2, Drer\fkbp1ab, Drer\fkbp1b, Drer\fkbp14, Drer\si:ch211-208h16.4, Drer\fkbp7, Drer\fkbp9, Drer\fkbp1aa" Scer\FPR2 "Cele\fkb-1, Cele\fkb-5, Cele\fkb-4, Cele\fkb-2, Cele\fkb-3, Cele\fkb-7" "Xtro\fkbp7, Xtro\fkbp9, Xtro\fkbp14, Xtro\fkbp15, Xtro\fkbp1b, Xtro\fkbp10, Xtro\fkbp3, Xtro\fkbp2" "Mmus\Fkbp11, Mmus\Fkbp7, Mmus\Fkbp10, Mmus\Fkbp3, Mmus\Fkbp1a, Mmus\Fkbp14, Mmus\Fkbp1b, Mmus\Fkbp9, Mmus\Fkbp15, Mmus\Fkbp2" "Hsap\FKBP3, Hsap\FKBP9, Hsap\FKBP15, Hsap\FKBP1B, Hsap\FKBP2, Hsap\FKBP14, Hsap\FKBP11, Hsap\FKBP10, Hsap\FKBP7" viable FBgn0039232 sosie sosie http://flybase.org/reports/FBgn0039232 protein_coding_gene - ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "BcDNA:RE20019, BcDNA:RE05274, sosie, CG13636, sie" - CG13636 11-Aug-17 DroID_v2017_08 - - - - - - "auditory perception defective,neurophysiology defective,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "egg chamber,nurse cell,female germline ring canal,follicle cell,dorsal appendage,maternal effect,mesothoracic tergum" FBgn0034095 CG15701 - http://flybase.org/reports/FBgn0034095 protein_coding_gene - - - CG15701 "IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site, IPR015943:WD40/YVTN repeat-like-containing domain" CG15701 11-Aug-17 DroID_v2017_08 "Drer\dnai1.1, Drer\dnai1.2, Drer\wdr60" - Cele\C27F2.1 - "Mmus\Dnaic1, Mmus\Wdr60" "Hsap\WDR60, Hsap\DNAI1" viable FBgn0038450 CG17560 - http://flybase.org/reports/FBgn0038450 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - "CT38785, CG17560" "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG17560 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far1, Mmus\Far2" "Hsap\FAR2, Hsap\FAR1" "viable,fertile" FBgn0264556 Gr39a Gustatory receptor 39a http://flybase.org/reports/FBgn0264556 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr39a, Gr39a.d, Gr39a.a, Gr39a.b, Gr39aD, Gr39aC, Gr39aB, Gr39aA, Gr39a.c, Gr39D2d, Gr39D2c, Gr39D2b, Gr39D2a, 39D2d, 39D2c, 39D2b, 39D2a, Gr39D2A, 39D.2d, 39D.2c, 39D.2b, 39D.2a, 39D.2, CG31622, GR39D.2, gene Y, l(2)k05106, GR39a" IPR013604:7TM chemoreceptor CG31622 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - FBgn0033278 CG14759 - http://flybase.org/reports/FBgn0033278 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14759 - CG14759 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025336 CG4882 - http://flybase.org/reports/FBgn0025336 - protein_coding_gene - - mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000483578 "GM14313, LD24471, UD1, anon-60Aa, CG4882" "IPR019266:Ribosomal protein S27, mitochondrial" CG4882 11-Aug-17 DroID_v2017_08 Drer\mrps27 - Cele\K11B4.1 - Mmus\Mrps27 Hsap\MRPS27 "viable,visible" trichogen cell DRSC04495 E -0.901445819 0.116960056 -1.67581019 0.021247903 0.346273091 -0.176971801 FBgn0024881 l(2)10206 lethal (2) 10206 http://flybase.org/reports/FBgn0024881 - gene - - - "10206, l(2)10206" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022146 l(2)k06021 lethal (2) k06021 http://flybase.org/reports/FBgn0022146 - gene - - - l(2)k06021 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266403 CR45043 - http://flybase.org/reports/FBgn0266403 non_protein_coding_gene - - - CR45043 - CR45043 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040319 Gclc Glutamate-cysteine ligase catalytic subunit http://flybase.org/reports/FBgn0040319 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Gclm glutamate-cysteine ligase activity ; GO:0004357 | inferred from sequence or structural similarity with SGD:S000003637 inferred from genetic interaction with SGD:S000003637 glutamate-cysteine ligase activity ; GO:0004357 | inferred from direct assay glutathione biosynthetic process ; GO:0006750 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype glutathione biosynthetic process ; GO:0006750 | inferred from sequence or structural similarity with SGD:S000003637 inferred from genetic interaction with SGD:S000003637 response to copper ion ; GO:0046688 | inferred from direct assay inferred from genetic interaction with ATP7 inferred from genetic interaction with Ctr1A perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay glutamate-cysteine ligase complex ; GO:0017109 | inferred from physical interaction with Gclm "DmGCLC, GCSh, DmGCSh, DmGCS, GCLc, Gcsh, Gcs, CG2259, Gclc, GCLC, GCL, gclc, 2259, GclC" IPR004308:Glutamate-cysteine ligase catalytic subunit CG2259 11-Aug-17 DroID_v2017_08 Drer\gclc Scer\GSH1 Cele\gcs-1 Xtro\gclc Mmus\Gclc Hsap\GCLC "viable,fertile,long lived,chemical resistant" FBgn0000786 fs(1)BP female sterile (1) BP http://flybase.org/reports/FBgn0000786 FBgn0000730 gene - - - "fs(1)BP2, fs(1)9F, fs(1)BP" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile ovary FBgn0010594 l(2)05315 lethal (2) 05315 http://flybase.org/reports/FBgn0010594 - gene - - - l(2)05315 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065250 l(2)SH2134 lethal (2) SH2134 http://flybase.org/reports/FBgn0065250 gene - - - "l(2)SH2134, l(2)SH2 2134" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030662 CG9220 - http://flybase.org/reports/FBgn0030662 protein_coding_gene acetylgalactosaminyltransferase activity ; GO:0008376 | inferred from electronic annotation with InterPro:IPR008428 acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement glucuronosyltransferase activity ; GO:0015020 | non-traceable author statement chondroitin sulfate biosynthetic process ; GO:0030206 | non-traceable author statement Golgi cisterna membrane ; GO:0032580 | inferred from electronic annotation with InterPro:IPR008428 "CG9220, dCHSY" "IPR008428:Chondroitin N-acetylgalactosaminyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases" CG9220 11-Aug-17 DroID_v2017_08 "Drer\b4galnt3b, Drer\csgalnact1b, Drer\b4galnt4b, Drer\chsy1, Drer\b4galnt3a, Drer\chsy3, Drer\b4galnt4a, Drer\csgalnact2, Drer\csgalnact1a" - "Cele\sqv-5, Cele\C17A2.3, Cele\C02H6.1" "Xtro\csgalnact1, Xtro\csgalnact2, Xtro\chsy3, Xtro\b4galnt4, Xtro\chsy1, Xtro\b4galnt3" "Mmus\Csgalnact2, Mmus\B4galnt3, Mmus\Csgalnact1, Mmus\B4galnt4, Mmus\Chsy3, Mmus\Chsy1" "Hsap\CHSY3, Hsap\CSGALNACT2, Hsap\CSGALNACT1, Hsap\CHSY1, Hsap\B4GALNT4, Hsap\B4GALNT3" "viable,body color defective" mesothoracic tergum DRSC20176 K -0.150094943 0.264371295 0.211329532 0.064967036 0.530027072 1.696075484 FBgn0030304 Cyp4g15 Cyp4g15 http://flybase.org/reports/FBgn0030304 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" - "152658_at, 4g15, CG11715, Cyp4g15" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG11715 11-Aug-17 DroID_v2017_08 "Drer\cyp26c1, Drer\cyp4t8, Drer\cyp46a1.4, Drer\cyp46a1.2, Drer\cyp20a1, Drer\cyp4v7, Drer\cyp46a1.3, Drer\cyp19a1b, Drer\LOC100329425, Drer\cyp46a1.1, Drer\cyp26b1, Drer\cyp4f3, Drer\cyp19a1a, Drer\cyp4v8, Drer\cyp26a1" "Scer\ERG11, Scer\DIT2, Scer\ERG5" "Cele\cyp-29A4, Cele\cyp-31A2, Cele\cyp-32B1, Cele\cyp-32A1, Cele\cyp-29A2, Cele\cyp-37A1, Cele\cyp-29A3, Cele\cyp-42A1, Cele\cyp-31A3, Cele\cyp-37B1" "Xtro\mgc108213, Xtro\cyp20a1, Xtro\LOC100487918, Xtro\cyp26a1, Xtro\cyp4f22, Xtro\cyp19a1, Xtro\cyp4b1, Xtro\LOC100488227, Xtro\cyp26b1, Xtro\cyp4v2, Xtro\cyp4b1.2, Xtro\cyp26c1, Xtro\cyp4f2" "Mmus\Cyp4v3, Mmus\Cyp20a1, Mmus\Cyp26c1, Mmus\Cyp4f39, Mmus\Cyp4x1, Mmus\Cyp4a31, Mmus\Cyp26a1, Mmus\Cyp4b1, Mmus\Cyp4a10, Mmus\Cyp4f14, Mmus\Cyp4f16, Mmus\Cyp4f40, Mmus\Cyp4a29, Mmus\Cyp4f17, Mmus\Cyp46a1, Mmus\Cyp4f13, Mmus\Cyp4f18, Mmus\Cyp26b1, Mmus\Cyp4a12a, Mmus\Cyp4a30b, Mmus\Cyp4f15, Mmus\Cyp19a1, Mmus\Cyp4a12b, Mmus\Cyp4a32, Mmus\Cyp4a14, Mmus\Cyp51, Mmus\Cyp4f37" "Hsap\CYP46A1, Hsap\CYP26C1, Hsap\CYP4F3, Hsap\CYP4A22, Hsap\CYP26B1, Hsap\CYP4F12, Hsap\CYP4X1, Hsap\CYP4B1, Hsap\CYP26A1, Hsap\CYP4V2, Hsap\CYP4Z1, Hsap\CYP4F8, Hsap\CYP4F2, Hsap\CYP4F11, Hsap\CYP51A1, Hsap\CYP4A11, Hsap\CYP4F22, Hsap\CYP19A1, Hsap\CYP20A1" viable FBgn0050263 stum stumble http://flybase.org/reports/FBgn0050263 protein_coding_gene - proprioception ; GO:0019230 | inferred from mutant phenotype taxis ; GO:0042330 | inferred from mutant phenotype sensory perception of mechanical stimulus ; GO:0050954 | inferred from mutant phenotype sensory dendrite ; GO:0071683 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay "CT35864, CG15679, CG15677, stum, CG30263, mdcds_15969" IPR026673:SPEC3/Stum CG30263 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-59a8.4 - "Cele\Y51H7BR.7, Cele\Y97E10AL.1" - Mmus\Stum Hsap\STUM "uncoordinated,neurophysiology defective,neuroanatomy defective,viable" "dendrite,multidendritic neuron" FBgn0026202 moch mochtegern http://flybase.org/reports/FBgn0026202 - gene molecular_function ; GO:0003674 | no biological data available central nervous system development ; GO:0007417 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mog, moch" - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic/larval central nervous system,commissure,midline glial cell,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron" FBgn0060927 l(3)S042202 lethal (3) S042202 http://flybase.org/reports/FBgn0060927 gene - - - "0422/02, l(3)S042202" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031143 CG1532 - http://flybase.org/reports/FBgn0031143 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG1532 IPR029068:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CG1532 11-Aug-17 DroID_v2017_08 Drer\glod4 - Cele\glod-4 Xtro\glod4 Mmus\Glod4 Hsap\GLOD4 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0002179 l(3)62Bc lethal (3) 62Bc http://flybase.org/reports/FBgn0002179 FBgn0011451 gene - - - "dre2, l(3)dre2, l(3)62Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0028900 CG18518 - http://flybase.org/reports/FBgn0028900 protein_coding_gene - - - "DS02252.4, BG:DS02252.4, CG18518" - CG18518 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060630 l(3)S085706 lethal (3) S085706 http://flybase.org/reports/FBgn0060630 gene - - - "0857/06, l(3)S085706" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005493 l(1)ts4931B lethal (1) ts4931B http://flybase.org/reports/FBgn0005493 - gene - - - l(1)ts4931B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0032646 mEFTs mitochondrial translation elongation factor Ts http://flybase.org/reports/FBgn0032646 protein_coding_gene translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with UniProtKB:P43897 translation elongation factor activity ; GO:0003746 | inferred from biological aspect of ancestor with PANTHER:PTN000201459 translational elongation ; GO:0006414 | inferred from sequence or structural similarity with UniProtKB:P43897 mitochondrial translational elongation ; GO:0070125 | inferred from biological aspect of ancestor with PANTHER:PTN000201460 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P43897 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000201460 "mtEF-Ts, CG6412, mEFTs" "IPR001816:Translation elongation factor EFTs/EF1B, IPR009060:UBA-like, IPR018101:Translation elongation factor Ts, conserved site, IPR014039:Translation elongation factor EFTs/EF1B, dimerisation" CG6412 11-Aug-17 DroID_v2017_08 Drer\tsfm - Cele\tsfm-1 Xtro\tsfm Mmus\Tsfm Hsap\TSFM "viable,fertile,visible" trichogen cell FBgn0034893 mRpL43 mitochondrial ribosomal protein L43 http://flybase.org/reports/FBgn0034893 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AI075733 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AI075733 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AI075733 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CI-B8, CG5479, BcDNA:RE35686, mRpL-CI-B8, mRpL43, mRPL43" "IPR007741:Ribosomal protein/NADH dehydrogenase domain, IPR012336:Thioredoxin-like fold" CG5479 11-Aug-17 DroID_v2017_08 Drer\mrpl43 Scer\MRPL51 Cele\mrpl-34 Xtro\mrpl43 Mmus\Mrpl43 Hsap\MRPL43 "viable,visible" trichogen cell FBgn0028396 TotA Turandot A http://flybase.org/reports/FBgn0028396 protein_coding_gene - response to water deprivation ; GO:0009414 | inferred from expression pattern response to UV ; GO:0009411 | inferred from direct assay response to mercury ion ; GO:0046689 | inferred from mutant phenotype response to heat ; GO:0009408 | traceable author statement cellular response to oxidative stress ; GO:0034599 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern response to oxidative stress ; GO:0006979 | inferred from direct assay cellular response to heat ; GO:0034605 | inferred from expression pattern response to cold ; GO:0009409 | inferred from direct assay cellular response to mechanical stimulus ; GO:0071260 | inferred from expression pattern response to heat ; GO:0009408 | inferred from direct assay cellular response to UV ; GO:0034644 | inferred from expression pattern response to mechanical stimulus ; GO:0009612 | inferred from direct assay response to methylmercury ; GO:0051597 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "TotA, Tot-A, totA, tot, Tot, Turt, CG31509, Tot A, DIM 31" IPR010825:Stress-inducible humoral factor Turandot CG31509 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,chemical resistant,viable" FBgn0051281 Tpl94D Transition protein-like 94D http://flybase.org/reports/FBgn0051281 protein_coding_gene - "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from expression pattern" chromatin ; GO:0000785 | inferred from sequence model nucleus ; GO:0005634 | inferred from direct assay "NEST:bs30g09, NEST:bs11b10, Tpl[94D], CG31281, tpl[94D], Tpl94D, tpl, tpl94D" "IPR009071:High mobility group box domain, IPR024460:Protamine-like" CG31281 11-Aug-17 DroID_v2017_08 - - - - - - DRSC13593 E -0.244308407 0.939920208 -2.212417984 -0.067406389 -0.075672292 -0.637809064 FBgn0052495 CG32495 - http://flybase.org/reports/FBgn0052495 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR004887, InterPro:IPR005615, InterPro:IPR013816, InterPro:IPR014042, InterPro:IPR014049 glutathione synthase activity ; GO:0004363 | inferred from electronic annotation with InterPro:IPR004887, InterPro:IPR005615, InterPro:IPR014042, InterPro:IPR014049" "cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype detoxification of arsenic-containing substance ; GO:0071722 | inferred from genetic interaction with GSS glutathione biosynthetic process ; GO:0006750 | inferred from electronic annotation with InterPro:IPR004887, InterPro:IPR005615, InterPro:IPR014042" - "CG32495, 32495, GS" "IPR014049:Glutathione synthase, N-terminal, eukaryotic, IPR014042:Glutathione synthase, alpha-helical, eukaryotic, IPR016185:Pre-ATP-grasp domain, IPR014709:Glutathione synthase domain, IPR004887:Glutathione synthase, substrate-binding, eukaryotic, IPR005615:Glutathione synthase" CG32495 11-Aug-17 DroID_v2017_08 Drer\gss Scer\GSH2 Cele\gss-1 Xtro\gss Mmus\Gss Hsap\GSS FBgn0011176 l(1)291-54 lethal (1) 291-54 http://flybase.org/reports/FBgn0011176 FBgn0010199 gene - - - "291-54, l(1)291-54" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0042085 Bap170 Brahma associated protein 170kD http://flybase.org/reports/FBgn0042085 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001606, InterPro:IPR003150 protein binding ; GO:0005515 | inferred from physical interaction with z transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060" "imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype inferred from genetic interaction with polybromo inferred from genetic interaction with polybromo, e(y)3 inferred from genetic interaction with polybromo, e(y)3 protein stabilization ; GO:0050821 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Raf inferred from genetic interaction with pnt inferred from genetic interaction with Ras85D inferred from genetic interaction with Egfr inferred from genetic interaction with vn inferred from genetic interaction with bs imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype negative regulation of chromatin silencing ; GO:0031936 | inferred from genetic interaction with Pc, polybromo" brahma complex ; GO:0035060 | inferred from direct assay PBAF complex ; GO:0070604 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "BAP170, CG3274, BcDNA:GH12174, Bap170, bap170, hfl" "IPR001606:ARID DNA-binding domain, IPR003150:DNA-binding RFX-type winged-helix domain, IPR016024:Armadillo-type fold, IPR011991:Winged helix-turn-helix DNA-binding domain" CG3274 11-Aug-17 DroID_v2017_08 Drer\arid2 - Cele\swsn-7 Xtro\arid2 Mmus\Arid2 Hsap\ARID2 "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage,visible,partially lethal - majority die,male limited,lethal,female limited,partially,fertile,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,eye photoreceptor cell,supernumerary,outer photoreceptor cell,photoreceptor cell R7,cone cell,leg,wing vein,ectopic,wing margin,wing hair,wing sensillum,mesothoracic tergum" FBgn0265586 CR44413 - http://flybase.org/reports/FBgn0265586 non_protein_coding_gene - - - CR44413 - CR44413 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024522 l(3)j1E6 lethal (3) j1E6 http://flybase.org/reports/FBgn0024522 - gene - - - l(3)j1E6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053302 Cpr31A Cuticular protein 31A http://flybase.org/reports/FBgn0053302 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG4791, Cpr31A, CG33302, CG4791-PB" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG33302 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0065277 l(2)SH2045 lethal (2) SH2045 http://flybase.org/reports/FBgn0065277 gene - - - "l(2)SH2045, l(2)SH2 2045" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014057 Su(tor)2-408 Su(tor)2-408 http://flybase.org/reports/FBgn0014057 - gene - - - Su(tor)2-408 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0085631 CG41360 - http://flybase.org/reports/FBgn0085631 protein_coding_gene - - - CG41360 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266539 CG45100 - http://flybase.org/reports/FBgn0266539 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45100, Dmel_Hdac3_uORF, Hdac3-5'utr" - CG45100 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052821 CR32821 - http://flybase.org/reports/FBgn0052821 pseudogene_attribute - - - "CG32821, CR32821" - CR32821 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029915 CG14434 - http://flybase.org/reports/FBgn0029915 protein_coding_gene - - - CG14434 "IPR023577:CYTH domain, IPR008173:Adenylyl cyclase CyaB, IPR033469:CYTH-like domain" CG14434 11-Aug-17 DroID_v2017_08 - - Cele\F35D11.4 - - - "viable,fertile" FBgn0060407 l(3)S130608 lethal (3) S130608 http://flybase.org/reports/FBgn0060407 gene - - - "1306/08, l(3)S130608" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267520 28SrRNA-Psi:CR45860 28S ribosomal RNA pseudogene:CR45860 http://flybase.org/reports/FBgn0267520 pseudogene_attribute - - - "28SrRNA-Psi:CR45860, CR45860" - CR45860 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051415 CG31415 - http://flybase.org/reports/FBgn0051415 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs07c11, CG31415" - CG31415 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030974 CG7358 - http://flybase.org/reports/FBgn0030974 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG7358 - CG7358 11-Aug-17 DroID_v2017_08 Drer\zc3h13 - - - Mmus\Zc3h13 Hsap\ZC3H13 "viable,visible" mesothoracic tergum FBgn0000065 Aldox89A Aldehyde oxidase at 89A http://flybase.org/reports/FBgn0000065 - gene - - - "AO, Ao-1, Aldox, Ao, Aox, AOX, aldox, lao, Aldox89A, Aldox-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "electrophoretic variant,slow,viable,fast" FBgn0028158 l(3)S041706 lethal (3) S041706 http://flybase.org/reports/FBgn0028158 gene - - - "0417/06, l(3)S041706" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037064 CG9389 - http://flybase.org/reports/FBgn0037064 protein_coding_gene inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from sequence or structural similarity with HGNC:6051 inositol monophosphate 1-phosphatase activity ; GO:0008934 | non-traceable author statement "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550, InterPro:IPR020552 inositol metabolic process ; GO:0006020 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol phosphate dephosphorylation ; GO:0046855 | inferred from sequence or structural similarity with HGNC:6051 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol phosphate dephosphorylation ; GO:0046855 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 dephosphorylation ; GO:0016311 | non-traceable author statement" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6051 "142336_at, IMP, CG9389" "IPR000760:Inositol monophosphatase-like, IPR033942:Inositol monophosphatase, IPR020550:Inositol monophosphatase, conserved site, IPR020552:Inositol monophosphatase, Lithium-sensitive, IPR020583:Inositol monophosphatase, metal-binding site" CG9389 11-Aug-17 DroID_v2017_08 "Drer\impa2, Drer\impa1" "Scer\INM2, Scer\INM1" Cele\ttx-7 "Xtro\impa1, Xtro\impa2" "Mmus\Impa2, Mmus\Impa1" "Hsap\IMPA1, Hsap\IMPA2" viable FBgn0001021 fs(3)A12 female sterile (3) A12 http://flybase.org/reports/FBgn0001021 - gene - - - fs(3)A12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0022303 l(1)L55.6 lethal (1) L55.6 http://flybase.org/reports/FBgn0022303 - gene - - - "L55.6, l(1)L55.6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065116 l(3)SH159 lethal (3) SH159 http://flybase.org/reports/FBgn0065116 gene - - - "l(3)SH159, l(2)SH3 159" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036450 Tdrd3 Tudor domain containing 3 http://flybase.org/reports/FBgn0036450 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR010304 mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR010304 lateral inhibition ; GO:0046331 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010304 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR010304 "CG13472, dTDRD3, Tdrd3" "IPR009060:UBA-like, IPR015940:Ubiquitin-associated domain, IPR002999:Tudor domain, IPR013894:RecQ mediated genome instability protein, N-terminal, IPR010304:Survival motor neuron, IPR033472:RecQ mediated genome instability protein, DUF1767" CG13472 11-Aug-17 DroID_v2017_08 "Drer\tdrd3, Drer\rmi1" Scer\RMI1 "Cele\rmh-2, Cele\Y50D4C.3, Cele\rmh-1" "Xtro\rmi1, Xtro\tdrd3" "Mmus\Rmi1, Mmus\Tdrd3" "Hsap\TDRD3, Hsap\RMI1" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0036156 CG11726 - http://flybase.org/reports/FBgn0036156 protein_coding_gene RNA strand annealing activity ; GO:0033592 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 ribosomal small subunit binding ; GO:0043024 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA strand-exchange activity ; GO:0034057 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 eukaryotic translation initiation factor 4F complex assembly ; GO:0097010 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 cytoplasmic translation ; GO:0002181 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 formation of translation preinitiation complex ; GO:0001731 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 "cg11726, CG11726" "IPR000504:RNA recognition motif domain, IPR033107:Eukaryotic translation initiation factor 4B" CG11726 11-Aug-17 DroID_v2017_08 "Drer\cirbpa, Drer\eif4ba, Drer\rbm34, Drer\trnau1apa, Drer\wu:fq32h04, Drer\eif4h, Drer\hnrnpaba, Drer\ncoa5, Drer\eif4bb, Drer\hnrnpabb, Drer\raly, Drer\trnau1apb, Drer\hnrnpa3, Drer\hnrnpc, Drer\srsf10a, Drer\dazl, Drer\hnrnpd, Drer\zgc:55733, Drer\zcrb1, Drer\hnrnpa1b" "Scer\CWC2, Scer\TIF3, Scer\NAM8, Scer\NAB6, Scer\NGR1, Scer\MRN1, Scer\NOP12, Scer\MUD1, Scer\NOP6" - "Xtro\hnrnpa2b1, Xtro\hnrnpd, Xtro\eif4h, Xtro\rbm34, Xtro\dazl, Xtro\cirbp, Xtro\hnrnpa3, Xtro\ralyl, Xtro\hnrnpdl, Xtro\raly, Xtro\trnau1ap, Xtro\hnrnpab, Xtro\hnrnpc, Xtro\eif4b, Xtro\hnrnpa1" "Mmus\Tra2b, Mmus\Eif4h, Mmus\Hnrnpa3, Mmus\Hnrnpa1, Mmus\Hnrnpa2b1, Mmus\Cirbp, Mmus\Gm21379, Mmus\Rbm34, Mmus\Hnrnpd, Mmus\Rbm31y, Mmus\Srsf10, Mmus\Hnrnpc, Mmus\Eif4b, Mmus\Raly, Mmus\Trnau1ap, Mmus\Hnrnpab, Mmus\Boll, Mmus\Dazl, Mmus\Zcrb1, Mmus\Slirp, Mmus\Srsf12" "Hsap\HNRNPAB, Hsap\EIF4H, Hsap\SRSF10, Hsap\EIF4B, Hsap\TRNAU1AP, Hsap\RBM3, Hsap\HNRNPA2B1, Hsap\DAZ2, Hsap\DAZ3, Hsap\HNRNPA3, Hsap\DAZL, Hsap\HNRNPCL1, Hsap\RBM34, Hsap\DAZ1, Hsap\RALY, Hsap\HNRNPD, Hsap\HNRNPC, Hsap\DAZ4, Hsap\RALYL, Hsap\SLIRP, Hsap\HNRNPA1, Hsap\CIRBP, Hsap\BOLL, Hsap\HNRNPA1L2" viable FBgn0264835 CR44043 - http://flybase.org/reports/FBgn0264835 non_protein_coding_gene - - - CR44043 - CR44043 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067875 Mod(Prat:bw)3-11 Mod(Prat:bw)3-11 http://flybase.org/reports/FBgn0067875 gene - - - "Mod-3-11, Mod(Prat:bw)3-11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265063 CG44174 - http://flybase.org/reports/FBgn0265063 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44174, lincRNA.811" - CG44174 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262429 mir-13a mir-13a stem loop http://flybase.org/reports/FBgn0262429 miRNA_gene - - polysome ; GO:0005844 | non-traceable author statement "13a, mir-13a, CR42984, miR-13, miR-13a, miR13a, CR32931, MiR-13a, CR33566, mir-13a*, mir-13aS, mir-13, dme-mir-13a, dme-miR-13a" - CR42984 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage "visible,partially lethal - majority die,some die during pharate adult stage,lethal" wing FBgn0085818 CR41608 - http://flybase.org/reports/FBgn0085818 rRNA_gene - - - CR41608 - CR41608 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263839 CR43701 - http://flybase.org/reports/FBgn0263839 non_protein_coding_gene - - - "CR43701, ncRNA_54" - CR43701 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262901 CR43256 - http://flybase.org/reports/FBgn0262901 non_protein_coding_gene - - - CR43256 - CR43256 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261571 CG42685 - http://flybase.org/reports/FBgn0261571 protein_coding_gene - - - "CG42685, BG:DS07721.6, DS07721.6, CG12636, CG33482" "IPR001024:PLAT/LH2 domain, IPR002859:PKD/REJ-like domain" CG42685 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032834 CG13965 - http://flybase.org/reports/FBgn0032834 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay CG13965 - CG13965 11-Aug-17 DroID_v2017_08 - - - - - Hsap\MUCL1 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0028378 fs(1)3B fs(1)3B http://flybase.org/reports/FBgn0028378 gene - - - fs(1)3B - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0023536 CG3156 - http://flybase.org/reports/FBgn0023536 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:Q9NRK6 transporter activity ; GO:0005215 | inferred from sequence or structural similarity with UniProtKB:Q9NRK6" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:Q9NRK6 heme biosynthetic process ; GO:0006783 | inferred from sequence or structural similarity with UniProtKB:Q9NRK6 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011527 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q9NRK6 "EG:171D11.2, CG3156" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR030260:ATP-binding cassette subfamily B member 10" CG3156 11-Aug-17 DroID_v2017_08 "Drer\abcb4, Drer\abcb11a, Drer\abcb9, Drer\abcb11b, Drer\abcb10, Drer\abcb8, Drer\abcb5, Drer\si:dkey-57h18.2, Drer\tap1, Drer\abcb3l1" "Scer\MDL1, Scer\MDL2" "Cele\pgp-12, Cele\haf-8, Cele\haf-7, Cele\pgp-4, Cele\haf-4, Cele\pgp-2, Cele\pgp-1, Cele\pgp-6, Cele\haf-1, Cele\pgp-9, Cele\haf-6, Cele\pgp-7, Cele\haf-3, Cele\pgp-13, Cele\pgp-8, Cele\pgp-5, Cele\haf-2, Cele\pgp-14" "Xtro\abcb8, Xtro\tap1, Xtro\LOC100494740, Xtro\tap2" "Mmus\Tap2, Mmus\Abcb8, Mmus\Tap1, Mmus\Abcb11, Mmus\Abcb1a, Mmus\Abcb4, Mmus\Abcb1b, Mmus\Abcb10, Mmus\Abcb9, Mmus\Abcb5" "Hsap\ABCB11, Hsap\ABCB10, Hsap\ABCB9, Hsap\ABCB5, Hsap\ABCB4, Hsap\TAP2, Hsap\TAP1, Hsap\ABCB8" "viable,fertile" FBgn0052715 CG32715 - http://flybase.org/reports/FBgn0052715 protein_coding_gene - - - CG32715 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261701 CG42737 - http://flybase.org/reports/FBgn0261701 protein_coding_gene - - - "CG42737, CG43202" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060816 l(3)S052813b lethal (3) S052813b http://flybase.org/reports/FBgn0060816 gene - - - "0528/13, l(3)S052813b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027358 Tim9b Translocase of inner membrane 9b http://flybase.org/reports/FBgn0027358 FBgn0053066 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:Q9Y5J6 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q9Y5J6 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q9Y5J6 mitochondrial intermembrane space protein transporter complex ; GO:0042719 | inferred from biological aspect of ancestor with PANTHER:PTN000323427 "CG17767, Tim9, tim9, CG33066, Tim9b, Dromel_CG12788_CG17767_FBtr0074_tim9b_uORF" IPR004217:Tim10/DDP family zinc finger CG17767 11-Aug-17 DroID_v2017_08 "Drer\timm10b, Drer\timm9" "Scer\TIM9, Scer\TIM10" Cele\tin-9.2 Xtro\timm9 "Mmus\Timm10b, Mmus\Timm9" "Hsap\TIMM10B, Hsap\TIMM9" FBgn0265632 CG44439 - http://flybase.org/reports/FBgn0265632 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44439, lincRNA.265" - CG44439 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011810 l(3)s2976 lethal (3) s2976 http://flybase.org/reports/FBgn0011810 - gene - - - l(3)s2976 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019811 ftl2 flightless-2nd http://flybase.org/reports/FBgn0019811 - gene - - - ftl2 - - 11-Aug-17 DroID_v2017_08 - - - - - - flightless FBgn0266809 CR45271 - http://flybase.org/reports/FBgn0266809 non_protein_coding_gene - - - CR45271 - CR45271 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062605 Mod(var)1420 Mod(var)1420 http://flybase.org/reports/FBgn0062605 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1420, Mod(var)1420" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0030081 CG7246 - http://flybase.org/reports/FBgn0030081 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000588427 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000588427 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype" Pwp2p-containing subcomplex of 90S preribosome ; GO:0034388 | inferred from biological aspect of ancestor with PANTHER:PTN000588427 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000588427 "CG7246, dUTP6" "IPR003107:HAT (Half-A-TPR) repeat, IPR013949:U3 small nucleolar RNA-associated protein 6, IPR011990:Tetratricopeptide-like helical domain" CG7246 11-Aug-17 DroID_v2017_08 Drer\utp6 Scer\UTP6 - Xtro\utp6 Mmus\Utp6 Hsap\UTP6 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0039963 CG17444 - http://flybase.org/reports/FBgn0039963 protein_coding_gene - - - CG17444 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019823 eH3 eH3 http://flybase.org/reports/FBgn0019823 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available eH3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038619 CG7685 - http://flybase.org/reports/FBgn0038619 protein_coding_gene - N-glycan processing ; GO:0006491 | inferred from electronic annotation with InterPro:IPR026874 - CG7685 "IPR026874:Glucosidase 2 subunit beta, IPR028146:Glucosidase II beta subunit, N-terminal" CG7685 11-Aug-17 DroID_v2017_08 "Drer\prkcsh, Drer\gnptg" Scer\GTB1 Cele\ZK1307.8 "Xtro\gnptg, Xtro\prkcsh" "Mmus\Gnptg, Mmus\Prkcsh" "Hsap\PRKCSH, Hsap\GNPTG" "viable,fertile,visible" trichogen cell FBgn0050403 CG30403 - http://flybase.org/reports/FBgn0050403 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE26725, CG30403" "IPR004210:BESS motif, IPR006578:MADF domain" CG30403 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal" trichogen cell FBgn0046649 anon-38D.17 anon-38D.17 http://flybase.org/reports/FBgn0046649 gene - - - "38D.17, anon-38D.17" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019829 da::h da::h http://flybase.org/reports/FBgn0019829 - engineered_fusion_gene - - - da::h - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260090 2L3707 - http://flybase.org/reports/FBgn0260090 gene - - - 2L3707 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0052189 CG32189 - http://flybase.org/reports/FBgn0052189 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE39957, CG32189" - CG32189 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000128 Ars-region6 Autonomous replicating sequence region 6 http://flybase.org/reports/FBgn0000128 - region - - - "ars406, Ars-region6, Ars6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033589 CG13227 - http://flybase.org/reports/FBgn0033589 protein_coding_gene - - - "CG13227, cg13227" - CG13227 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC06347 I -1.627129847 0.591195776 -0.007441081 0.181026469 0.755501226 1.234691741 FBgn0051928 CG31928 - http://flybase.org/reports/FBgn0051928 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 chorion ; GO:0042600 | inferred from direct assay "CG10872, CG31928" "IPR001461:Aspartic peptidase A1 family, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG31928 11-Aug-17 DroID_v2017_08 "Drer\ctsd, Drer\zgc:103530, Drer\zgc:63831, Drer\ren, Drer\nots" "Scer\YPS3, Scer\BAR1, Scer\PEP4, Scer\YPS1, Scer\YPS6, Scer\MKC7, Scer\YGL258W-A, Scer\YPS7, Scer\YPS5" "Cele\asp-7, Cele\asp-2, Cele\asp-15, Cele\asp-6, Cele\asp-13, Cele\asp-8, Cele\asp-19, Cele\asp-18, Cele\asp-16, Cele\asp-5, Cele\asp-17, Cele\asp-14, Cele\asp-1, Cele\asp-4, Cele\asp-12, Cele\asp-10, Cele\asp-9, Cele\asp-3" "Xtro\ren, Xtro\pgc, Xtro\ctse, Xtro\ctsd, Xtro\napsa, Xtro\bace2, Xtro\LOC496913, Xtro\bace1, Xtro\pga4" "Mmus\Ctse, Mmus\Bace2, Mmus\Cym, Mmus\Ctsd, Mmus\Ren1, Mmus\Pgc, Mmus\Ren2, Mmus\Napsa, Mmus\Pga5, Mmus\Bace1" "Hsap\PGC, Hsap\BACE1, Hsap\BACE2, Hsap\CTSE, Hsap\CTSD, Hsap\PGA3, Hsap\NAPSA, Hsap\REN, Hsap\PGA5, Hsap\PGA4" viable FBgn0041601 g5 g5 http://flybase.org/reports/FBgn0041601 gene - - - g5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038788 Sirt2 Sirtuin 2 http://flybase.org/reports/FBgn0038788 protein_coding_gene NAD+ binding ; GO:0070403 | inferred from electronic annotation with InterPro:IPR003000 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR017328 NAD-dependent histone deacetylase activity ; GO:0017136 | inferred from direct assay histone deacetylase activity ; GO:0004407 | inferred from mutant phenotype protein deacetylation ; GO:0006476 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype histone deacetylation ; GO:0016575 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:10886 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:10886 "CG5085, dSIRT2, D.mel2, Sirt2, SIRT2" "IPR003000:Sirtuin family, IPR017328:Sirtuin, class I, IPR029035:DHS-like NAD/FAD-binding domain, IPR026590:Sirtuin family, catalytic core domain" CG5085 11-Aug-17 DroID_v2017_08 "Drer\sirt2, Drer\si:dkey-103i16.6, Drer\sirt3, Drer\sirt1" "Scer\HST1, Scer\HST3, Scer\HST2, Scer\SIR2" Cele\sir-2.1 "Xtro\sirt2, Xtro\sirt1, Xtro\sirt3.2" "Mmus\Sirt3, Mmus\Sirt1, Mmus\Sirt2" "Hsap\SIRT1, Hsap\SIRT2, Hsap\SIRT3" "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,viable" FBgn0029694 CG15375 - http://flybase.org/reports/FBgn0029694 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15375, mdcds_59461" - CG15375 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004702 l(2)56Fd lethal (2) 56Fd http://flybase.org/reports/FBgn0004702 - gene - - - "l(2)56F, l(2)56Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085349 CR34320 - http://flybase.org/reports/FBgn0085349 pseudogene_attribute - - - "CG34320, CR34320" - CR34320 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045856 e(Pi3K92E)delta e(Pi3K92E)delta http://flybase.org/reports/FBgn0045856 gene - - - "delta, e(Pi3K92E)delta" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028691 Rpn9 Regulatory particle non-ATPase 9 http://flybase.org/reports/FBgn0028691 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from biological aspect of ancestor with PANTHER:PTN000056911 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000056911 proteasome assembly ; GO:0043248 | inferred from biological aspect of ancestor with PANTHER:PTN000056911 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 "proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000002835 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000056911 proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000056911 proteasome complex ; GO:0000502 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000056911 proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9558 inferred from direct assay" "rpn9, CT28749, p39A, 718/06, Rpn94, 0718/06, Rpn4, CG10230, l(3)S071806, l(3)S071806b, Rpn9, PSMD13, S11" "IPR000717:Proteasome component (PCI) domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain" CG10230 11-Aug-17 DroID_v2017_08 Drer\psmd13 Scer\RPN9 Cele\rpn-9 Xtro\psmd13 Mmus\Psmd13 Hsap\PSMD13 "neuroanatomy defective,partially lethal - majority die,recessive,lethal,lethal - all die before end of pupal stage,some die during pupal stage" rhabdomere of eye photoreceptor cell DRSC27177 IEK -0.382995876 -2.534154536 -2.255090635 -1.028416817 0.736823151 1.621169621 FBgn0000198 blo bloated http://flybase.org/reports/FBgn0000198 FBgn0020848 gene - apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype integrin-mediated signaling pathway ; GO:0007229 | non-traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement - "kit, ba, ba[33f26], ba[2], blo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,poor" "wing,wing vein,ectopic,somatic clone,cell non-autonomous,macrochaeta" FBgn0060702 l(3)S071615 lethal (3) S071615 http://flybase.org/reports/FBgn0060702 gene - - - "0716/15, l(3)S071615" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002138 l(2)K255 lethal (2) K255 http://flybase.org/reports/FBgn0002138 - gene - - - l(2)K255 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0082974 snoRNA:Psi28S-3305c snoRNA:Psi28S-3305c http://flybase.org/reports/FBgn0082974 snoRNA_gene - - - "snoRNA:Psi28S-3305c, psi28s-3305c, CR34624" - CR34624 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067655 sd-13 sd-13 http://flybase.org/reports/FBgn0067655 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,somatic clone,lethal,recessive,phototaxis defective" FBgn0043857 rempD reduced mechanoreceptor potentials D http://flybase.org/reports/FBgn0043857 gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - rempD - - 11-Aug-17 DroID_v2017_08 - - - - - - "auditory perception defective,recessive,uncoordinated,locomotor behavior defective,behavior defective" "wing,leg,adult antennal nerve" FBgn0261479 nero nero http://flybase.org/reports/FBgn0261479 protein_coding_gene deoxyhypusine monooxygenase activity ; GO:0019135 | inferred from sequence or structural similarity with UniProtKB:Q9BU89 cell growth ; GO:0016049 | inferred from mutant phenotype positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype peptidyl-lysine modification to peptidyl-hypusine ; GO:0008612 | inferred from sequence or structural similarity with UniProtKB:Q9BU89 cell proliferation ; GO:0008283 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay "l(3)s1921, nero, DOHH, CG2245" "IPR004155:PBS lyase HEAT-like repeat, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR027517:Deoxyhypusine hydroxylase" CG2245 11-Aug-17 DroID_v2017_08 Drer\dohh Scer\LIA1 Cele\dohh-1 Xtro\dohh Mmus\Dohh Hsap\DOHH FBgn0024841 Pcd pterin-4a-carbinolamine dehydratase http://flybase.org/reports/FBgn0024841 FBgn0063104 protein_coding_gene 4-alpha-hydroxytetrahydrobiopterin dehydratase activity ; GO:0008124 | inferred from electronic annotation with InterPro:IPR001533 tetrahydrobiopterin biosynthetic process ; GO:0006729 | inferred from electronic annotation with InterPro:IPR001533 - "PCD, CG1963, BcDNA:LP07248, Pcd" IPR001533:Transcriptional coactivator/pterin dehydratase CG1963 11-Aug-17 DroID_v2017_08 Drer\pcbd1 Scer\YHL018W Cele\pcbd-1 Xtro\pcbd1 "Mmus\Pcbd1, Mmus\Pcbd2" "Hsap\PCBD1, Hsap\PCBD2" "viable,fertile,lethal,partially lethal - majority die,visible" trichogen cell DRSC16785 I -0.240113592 2.581568071 0.488008241 1.463786069 -1.476387284 -0.349172999 FBgn0032431 CG5435 - http://flybase.org/reports/FBgn0032431 protein_coding_gene - - - "BcDNA:AT11334, CG5435" IPR022179:Protein of unknown function DUF3695 CG5435 11-Aug-17 DroID_v2017_08 Drer\si:ch211-163l21.7 - - - Mmus\1700013F07Rik Hsap\C1orf194 viable FBgn0265749 CR44556 - http://flybase.org/reports/FBgn0265749 non_protein_coding_gene - - - "CR44556, lincRNA.978" - CR44556 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003582 Su(Ste) Suppressor of Stellate http://flybase.org/reports/FBgn0003582 "FBgn0025265, FBgn0005668" - "protein kinase regulator activity ; GO:0019887 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150" male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype "protein kinase CK2 complex ; GO:0005956 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150" "HMR, HMR-element, cry, PSY, SuSte, anon-EST:fe1B7, Ste, Su(Ste), Su(ste), rasi4, su(ste), rasi1" "IPR016149:Casein kinase II, regulatory subunit, alpha-helical, IPR000704:Casein kinase II, regulatory subunit" - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,reduced,meiotic cell cycle defective,male" FBgn0028560 sut4 sugar transporter 4 http://flybase.org/reports/FBgn0028560 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "CG1380, sut4" "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG1380 11-Aug-17 DroID_v2017_08 "Drer\LOC797974, Drer\slc2a8, Drer\slc2a12, Drer\LOC101882338, Drer\si:dkey-229d11.5, Drer\slc2a13b, Drer\slc2a10, Drer\si:ch1073-263o8.2, Drer\slc2a6" "Scer\HXT2, Scer\HXT15, Scer\YFL040W, Scer\HXT17, Scer\YDR387C, Scer\ENB1, Scer\HXT16, Scer\HXT11, Scer\HXT9, Scer\HXT5, Scer\HXT7, Scer\HXT10, Scer\ATR1, Scer\MAL11, Scer\AZR1, Scer\HXT14, Scer\HXT4, Scer\SGE1, Scer\HXT8, Scer\ITR1, Scer\VBA3, Scer\MAL31, Scer\GEX2, Scer\ITR2, Scer\GEX1, Scer\GAL2, Scer\RGT2, Scer\VBA5, Scer\HXT3, Scer\YMR279C, Scer\MPH2, Scer\HXT6, Scer\SNF3, Scer\STL1, Scer\VBA1, Scer\YDL199C, Scer\HXT13, Scer\MPH3, Scer\VBA4, Scer\HXT1, Scer\VBA2" "Cele\M01G12.14, Cele\hmit-1.3, Cele\Y61A9LA.1, Cele\M01G12.9, Cele\Y66D12A.21" "Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a12, Xtro\slc2a10" "Mmus\Slc2a6, Mmus\Gm5615, Mmus\Pate4, Mmus\Slc2a8, Mmus\Gm7257, Mmus\Slc2a13, Mmus\Gm17689, Mmus\Pate1, Mmus\Acrv1, Mmus\Slc2a12, Mmus\1700013H16Rik, Mmus\Tm2d1, Mmus\Slc2a10, Mmus\Pate3" "Hsap\SLC2A8, Hsap\SLC2A10, Hsap\PATE4, Hsap\TM2D1, Hsap\PATE3, Hsap\PATE1, Hsap\SLC2A13, Hsap\SLC2A12, Hsap\SLC2A6, Hsap\ACRV1" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0014028 SdhB "Succinate dehydrogenase, subunit B (iron-sulfur)" http://flybase.org/reports/FBgn0014028 - protein_coding_gene "electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001041, InterPro:IPR025192 3 iron, 4 sulfur cluster binding ; GO:0051538 | inferred from sequence or structural similarity with UniProtKB:Q007T0 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from sequence or structural similarity with UniProtKB:Q007T0 succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from sequence or structural similarity with UniProtKB:P21912 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from sequence or structural similarity with UniProtKB:Q007T0 ubiquinone binding ; GO:0048039 | inferred from sequence or structural similarity with UniProtKB:Q007T0" "tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P21912 mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from direct assay aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000229864" "microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from sequence or structural similarity with UniProtKB:P21912 mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000229867 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from sequence or structural similarity with UniProtKB:Q007T0 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q007T0" "sdhB, Ip, SDH-IP, SDHb, CG3283, SdhB, SDH, SDH-Ip, SDH-B, DHSB, CII-SDHB, Sdhb" "IPR025192:Succinate dehydogenase/fumarate reductase N-terminal, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR004489:Succinate dehydrogenase/fumarate reductase iron-sulphur protein, IPR006058:2Fe-2S ferredoxin, iron-sulphur binding site, IPR009051:Alpha-helical ferredoxin, IPR012675:Beta-grasp domain, IPR017896:4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR017900:4Fe-4S ferredoxin, iron-sulphur binding, conserved site" CG3283 11-Aug-17 DroID_v2017_08 Drer\sdhb Scer\SDH2 Cele\sdhb-1 Xtro\sdhb Mmus\Sdhb Hsap\SDHB " larval stage && adult stage , adult stage " " adult thorax

, adult head

" "viable,fertile,gravitaxis defective,stress response defective" "mitochondrion,mitochondrial crista,flight muscle" FBgn0024859 l(3)96Bc lethal (3) 96Bc http://flybase.org/reports/FBgn0024859 - gene - - - l(3)96Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259530 GG01329 - http://flybase.org/reports/FBgn0259530 gene - - - GG01329 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible proboscis FBgn0001849 l(1)ts5141 lethal (1) ts5141 http://flybase.org/reports/FBgn0001849 - gene - - - l(1)ts5141 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0037123 CG14569 - http://flybase.org/reports/FBgn0037123 protein_coding_gene - - - CG14569 IPR032011:Domain of unknown function DUF4794 CG14569 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265943 CR44730 - http://flybase.org/reports/FBgn0265943 non_protein_coding_gene - - - "lincRNA.133, CR44730" - CR44730 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037763 CG16904 - http://flybase.org/reports/FBgn0037763 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available CG16904 "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG16904 11-Aug-17 DroID_v2017_08 "Drer\hsd17b8, Drer\elovl7b, Drer\elovl4a, Drer\elovl2, Drer\elovl1a, Drer\elovl8a, Drer\elovl5, Drer\elovl4b, Drer\elovl1b, Drer\elovl7a, Drer\zgc:101858, Drer\elovl8b, Drer\dhrs7" "Scer\ELO3, Scer\ELO1, Scer\ELO2" "Cele\dhs-14, Cele\C06E4.3, Cele\F25D1.5, Cele\Y47G6A.21, Cele\dhs-25, Cele\dhs-11, Cele\ZK829.1, Cele\F26D2.15, Cele\F28H7.2, Cele\Y47G6A.22" "Xtro\dhrs7, Xtro\cbr4, Xtro\elovl7, Xtro\MGC79752, Xtro\elovl1, Xtro\elovl5, Xtro\elovl2, Xtro\hsd17b8" "Mmus\Elovl4, Mmus\H2-Ke6, Mmus\Elovl5, Mmus\Elovl2, Mmus\Elovl1, Mmus\Dhrs7, Mmus\Elovl7, Mmus\Cbr4" "Hsap\HSD17B8, Hsap\DHRS7, Hsap\ELOVL5, Hsap\ELOVL1, Hsap\ELOVL7, Hsap\ELOVL2, Hsap\CBR4, Hsap\ELOVL4" DRSC25306 K 0.582475653 0.037152286 -0.283659855 0.129217217 1.789222779 1.051342966 FBgn0085447 sif still life http://flybase.org/reports/FBgn0085447 protein_coding_gene "signal transducer activity, downstream of receptor ; GO:0005057 | inferred from electronic annotation with InterPro:IPR003116 Rac guanyl-nucleotide exchange factor activity ; GO:0030676 | inferred from sequence or structural similarity with MGI:MGI:103306" regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype regulation of synapse structure or activity ; GO:0050803 | traceable author statement actin cytoskeleton organization ; GO:0030036 | inferred from direct assay regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with MGI:MGI:103306 regulation of axonogenesis ; GO:0050770 | inferred from mutant phenotype regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with LIMK1 synapse ; GO:0045202 | inferred from direct assay "CG34418, SIF, RhoGEF, CG5406, slf, CG5256, sif, CG32414, Sif, Dm_3L:26493, lincRNA.447" "IPR000219:Dbl homology (DH) domain, IPR001331:Guanine-nucleotide dissociation stimulator, CDC24, conserved site, IPR000697:WH1/EVH1 domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR001478:PDZ domain, IPR003116:Raf-like Ras-binding" CG34418 11-Aug-17 DroID_v2017_08 "Drer\arhgef9a, Drer\sestd1, Drer\vav2, Drer\dnmbp, Drer\tiam2a, Drer\arhgef37, Drer\arhgef9b, Drer\pex13, Drer\tiam1a, Drer\LOC101886482, Drer\prex1, Drer\tiam1b, Drer\spata13, Drer\vav3b, Drer\arhgef4" "Scer\PEX13, Scer\CDC24" "Cele\vav-1, Cele\prx-13, Cele\tiam-1, Cele\Y37A1B.17, Cele\uig-1" Xtro\tiam1 "Mmus\Plekhg1, Mmus\Tiam1, Mmus\Spata13, Mmus\Pex13, Mmus\Vav1, Mmus\Tiam2, Mmus\Arhgef38, Mmus\Arhgef4, Mmus\Arhgef37, Mmus\Prex1, Mmus\Arhgef9, Mmus\Dnmbp, Mmus\Plekhg2, Mmus\Sestd1, Mmus\Plekhg3, Mmus\Vav3, Mmus\Vav2" "Hsap\PREX1, Hsap\PLEKHG3, Hsap\PLEKHG2, Hsap\SESTD1, Hsap\ARHGEF37, Hsap\PEX13, Hsap\ARHGEF4, Hsap\VAV3, Hsap\VAV2, Hsap\ARHGEF38, Hsap\SPATA13, Hsap\ARHGEF9, Hsap\VAV1, Hsap\TIAM2, Hsap\TIAM1, Hsap\PLEKHG1, Hsap\DNMBP" " embryonic stage | stage 17 , embryonic stage | stage 14 " " ventral nerve cord

, embryonic brain

, embryonic central nervous system | segmentally repeated pattern

, embryonic central nervous system | restricted

" " embryonic stage | stage 17 , adult stage , larval stage | third instar " " neuropil

, medulla neuropil

, ventral nerve cord

, lobula plate neuropil

, bouton &&of neuromuscular junction

, lamina neuropil

" FBgn0052152 CG32152 - http://flybase.org/reports/FBgn0052152 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR025799 protein methylation ; GO:0006479 | inferred from electronic annotation with InterPro:IPR025799 - CG32152 "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR025799:Protein arginine N-methyltransferase" CG32152 11-Aug-17 DroID_v2017_08 "Drer\LOC556054, Drer\prmt6, Drer\prmt1, Drer\prmt3, Drer\prmt8b" Scer\HMT1 - "Xtro\prmt1, Xtro\prmt3, Xtro\prmt6, Xtro\prmt8" "Mmus\Prmt6, Mmus\Prmt1, Mmus\Prmt3, Mmus\Prmt2, Mmus\Prmt8" "Hsap\PRMT2, Hsap\PRMT3, Hsap\PRMT8, Hsap\PRMT6, Hsap\PRMT1" "viable,fertile" FBgn0015841 Vm39DE Vm39DE http://flybase.org/reports/FBgn0015841 - gene - - - "T[[1]], Vm39DE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260645 CG42537 - http://flybase.org/reports/FBgn0260645 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG42537, CG10284, BRG-A3" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42537 11-Aug-17 DroID_v2017_08 "Drer\r3hdml, Drer\crispld1b, Drer\LOC100536500, Drer\crispld1a, Drer\pi15b, Drer\glipr1b, Drer\glipr2, Drer\pi15a, Drer\wu:fb59d01, Drer\crispld2, Drer\glipr2l" "Scer\PRY3, Scer\PRY1, Scer\PRY2" - "Xtro\MGC108118, Xtro\crisp2, Xtro\crispld2, Xtro\glipr2, Xtro\r3hdml, Xtro\crisp3, Xtro\crisp1" "Mmus\Clec18a, Mmus\Crisp4, Mmus\Pi16, Mmus\Crisp2, Mmus\Crispld1, Mmus\Glipr1, Mmus\Crisp1, Mmus\Crisp3, Mmus\Glipr1l1, Mmus\Crispld2, Mmus\Glipr2, Mmus\R3hdml, Mmus\Pi15, Mmus\Glipr1l2" "Hsap\GLIPR1L1, Hsap\CRISP1, Hsap\GLIPR1, Hsap\CLEC18B, Hsap\CLEC18C, Hsap\GLIPR2, Hsap\CLEC18A, Hsap\PI15, Hsap\CRISPLD1, Hsap\CRISP2, Hsap\GLIPR1L2, Hsap\R3HDML, Hsap\CRISPLD2, Hsap\PI16" FBgn0028036 l(3)S101206b lethal (3) S101206b http://flybase.org/reports/FBgn0028036 gene - - - "1012/06, l(3)S101206, l(3)S101206b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0265900 CR44689 - http://flybase.org/reports/FBgn0265900 non_protein_coding_gene - - - CR44689 - CR44689 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065470 l(2)SH1334 lethal (2) SH1334 http://flybase.org/reports/FBgn0065470 gene - - - "l(2)SH1334, l(2)SH2 1334" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263590 CR43615 - http://flybase.org/reports/FBgn0263590 non_protein_coding_gene - - - CR43615 - CR43615 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053057 CG33057 - http://flybase.org/reports/FBgn0053057 protein_coding_gene "transferase activity, transferring phosphorus-containing groups ; GO:0016772 | inferred from electronic annotation with InterPro:IPR002745" "tRNA splicing, via endonucleolytic cleavage and ligation ; GO:0006388 | inferred from electronic annotation with InterPro:IPR002745" - CG33057 IPR002745:Phosphotransferase KptA/Tpt1 CG33057 11-Aug-17 DroID_v2017_08 Drer\trpt1 Scer\TPT1 "Cele\nhr-72, Cele\nhr-73, Cele\nhr-235, Cele\nhr-74, Cele\nhr-82, Cele\nhr-251, Cele\M02B7.2, Cele\nhr-113, Cele\nhr-89, Cele\R02D3.8, Cele\nhr-264, Cele\nhr-217, Cele\nhr-81" Xtro\trpt1 "Mmus\Trpt1, Mmus\Eri3" "Hsap\ERI3, Hsap\TRPT1" "viable,fertile" FBgn0085766 CR40679 - http://flybase.org/reports/FBgn0085766 rRNA_gene - - - CR40679 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263021 CG43316 - http://flybase.org/reports/FBgn0263021 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43316, CG13169" - CG43316 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069077 tkv::wit tkv::wit http://flybase.org/reports/FBgn0069077 engineered_fusion_gene - - - tkv::wit - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003980 Vm26Ab Vitelline membrane 26Ab http://flybase.org/reports/FBgn0003980 - protein_coding_gene - chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from expression pattern vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype egg activation ; GO:0007343 | inferred from mutant phenotype vitelline envelope ; GO:0060388 | inferred from direct assay vitelline envelope ; GO:0060388 | inferred from physical interaction with Vml "Vm26Ab, sV23, fs(2)QJ42, VM26A.2, Dm sV23, Sv23, sV26, Vm26A, TU-4, sv23, CG9046, DIM 29" IPR013135:Vitelline membrane cysteine-rich domain CG9046 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage | stage S8-11 , adult stage && oogenesis stage " follicle cell

" oogenesis stage | stage S9-14 , embryonic stage " vitelline membrane

"female sterile,female semi-sterile" "endochorion,egg" FBgn0085280 CG34251 - http://flybase.org/reports/FBgn0085280 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34251 - CG34251 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034915 eIF6 eukaryotic translation initiation factor 6 http://flybase.org/reports/FBgn0034915 protein_coding_gene ribosome binding ; GO:0043022 | inferred from electronic annotation with InterPro:IPR002769 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity ribosomal large subunit binding ; GO:0043023 | inferred from biological aspect of ancestor with PANTHER:PTN000082061 mature ribosome assembly ; GO:0042256 | inferred from electronic annotation with InterPro:IPR002769 cellular response to starvation ; GO:0009267 | inferred from expression pattern translational initiation ; GO:0006413 | inferred from sequence or structural similarity maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000082061 maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000082061 ribosomal subunit export from nucleus ; GO:0000054 | inferred from biological aspect of ancestor with PANTHER:PTN000082061 assembly of large subunit precursor of preribosome ; GO:1902626 | inferred from biological aspect of ancestor with PANTHER:PTN000082061 "nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000082061 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000082061 cytosol ; GO:0005829 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000082061" "eif6, CG17611, l(2)k13214, anon-WO0172774.155, anon-WO0172774.153, eIF6, DeIF6, elF6" IPR002769:Translation initiation factor IF6 CG17611 11-Aug-17 DroID_v2017_08 Drer\eif6 Scer\TIF6 Cele\eif-6 Xtro\eif6 Mmus\Eif6 Hsap\EIF6 "visible,lethal,recessive,partially lethal,some die during pupal stage" "wing,sex comb,tarsal segment" FBgn0069315 X-189-23 X-189-23 http://flybase.org/reports/FBgn0069315 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-189-23 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0014970 jal jalapeno http://flybase.org/reports/FBgn0014970 - gene - - - jal - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053362 5SrRNA:CR33362 5SrRNA:CR33362 http://flybase.org/reports/FBgn0053362 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33362, 5SrRNA:CR33362" - CR33362 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003103 PL(3)sp-T1 Polygenic locus sternopleural T1 http://flybase.org/reports/FBgn0003103 - gene - - - "PL(3)sp[T1], 3a, PL(3)sp-T1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013310 PC-Pld Phosphatidylcholine-specific phospholipase-D http://flybase.org/reports/FBgn0013310 - gene phospholipase D activity ; GO:0004630 | inferred from direct assay - - PC-Pld - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052021 CG32021 - http://flybase.org/reports/FBgn0052021 protein_coding_gene - - - "CG32021, BcDNA:SD15619" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0265873 CR44662 - http://flybase.org/reports/FBgn0265873 non_protein_coding_gene - - - "lincRNA.996, CR44662" - CR44662 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052641 CG32641 - http://flybase.org/reports/FBgn0052641 protein_coding_gene - - - CG32641 "IPR001623:DnaJ domain, IPR018253:DnaJ domain, conserved site" CG32641 11-Aug-17 DroID_v2017_08 Drer\zgc:122979 "Scer\JJJ2, Scer\HLJ1, Scer\JJJ3" Cele\dnj-26 - Mmus\4930503B20Rik - DRSC22885 K -0.086617103 -1.032778946 0.011911982 0.252530775 -1.830134857 -0.72855551 FBgn0030634 CG9164 - http://flybase.org/reports/FBgn0030634 protein_coding_gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9164 IPR027417:P-loop containing nucleoside triphosphate hydrolase CG9164 11-Aug-17 DroID_v2017_08 "Drer\wscd1a, Drer\wscd2, Drer\wscd1b" "Scer\WSC3, Scer\WSC2, Scer\SLG1, Scer\WSC4" "Cele\sqv-6, Cele\F52D2.7" "Xtro\wscd1, Xtro\wscd2" "Mmus\Kremen2, Mmus\Wscd2, Mmus\Wscd1" "Hsap\KREMEN2, Hsap\WSCD2, Hsap\WSCD1" "viable,fertile" FBgn0043000 CycB::pim CycB::pim http://flybase.org/reports/FBgn0043000 engineered_fusion_gene - - - CycB::pim - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,wild-type" FBgn0259864 Su(Ste):CR42433 Su(Ste):CR42433 http://flybase.org/reports/FBgn0259864 non_protein_coding_gene - - - "Su(Ste):CR42433, RR42328, CR42433" - CR42433 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022240 l(2)k02501 lethal (2) k02501 http://flybase.org/reports/FBgn0022240 - gene - - - l(2)k02501 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085459 CG34430 - http://flybase.org/reports/FBgn0085459 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34430, CG14766" IPR006214:Bax inhibitor 1-related CG34430 11-Aug-17 DroID_v2017_08 "Drer\tmbim4, Drer\tmbim1, Drer\LOC566927, Drer\grinaa, Drer\zgc:110410, Drer\faim2a, Drer\grinab, Drer\faim2b, Drer\si:ch211-284o19.8" Scer\BXI1 "Cele\xbx-6, Cele\tag-120, Cele\Y42H9AR.2" "Xtro\tmbim1, Xtro\tmbim4, Xtro\faim2" "Mmus\Tmbim4, Mmus\Tmbim7, Mmus\Tmbim1, Mmus\Faim2, Mmus\Grina" "Hsap\GRINA, Hsap\FAIM2, Hsap\TMBIM1, Hsap\TMBIM4" FBgn0028165 l(3)S032412 lethal (3) S032412 http://flybase.org/reports/FBgn0028165 gene - - - "0324/12, l(3)S032412" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060749 l(3)S065109 lethal (3) S065109 http://flybase.org/reports/FBgn0060749 gene - - - "0651/09, l(3)S065109" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0065904 l(2)SH0194 lethal (2) SH0194 http://flybase.org/reports/FBgn0065904 gene - - - l(2)SH0194 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014973 l(1)13Fc lethal (1) 13Fc http://flybase.org/reports/FBgn0014973 - gene - - - "VIII, l(1)VIII, l(1)13Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058471 CR40471 - http://flybase.org/reports/FBgn0058471 non_protein_coding_gene - - - CR40471 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265896 CR44685 - http://flybase.org/reports/FBgn0265896 non_protein_coding_gene - - - "CR44685, lincRNA.635" - CR44685 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013758 C8.5 C8.5 http://flybase.org/reports/FBgn0013758 - gene - - - "T-C8.5, C8.5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050109 CG30109 - http://flybase.org/reports/FBgn0050109 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN000481815 CG30109 IPR007918:Mitochondrial distribution/morphology family 35/apoptosis CG30109 11-Aug-17 DroID_v2017_08 Drer\triap1 Scer\MDM35 Cele\T09A5.7 Xtro\triap1 Mmus\Triap1 Hsap\TRIAP1 "viable,fertile" FBgn0082683 E(ftz)2955 E(ftz)2955 http://flybase.org/reports/FBgn0082683 gene - - - "2955, E(ftz)2955" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033928 Arc2 Arc2 http://flybase.org/reports/FBgn0033928 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD11637, anon-WO0118547.456, Arc2, CG13941, dARC2, dArc2" - CG13941 11-Aug-17 DroID_v2017_08 "Drer\zgc:113436, Drer\oard1" - "Cele\F54G2.2, Cele\W08F4.12, Cele\fbxb-37" - "Mmus\Oard1, Mmus\Arc" "Hsap\OARD1, Hsap\ARC" "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0021891 l(2)k13211 lethal (2) k13211 http://flybase.net/reports/FBgn0021891.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0023088 eggroll eggroll http://flybase.org/reports/FBgn0023088 - gene - - - eggroll - - 11-Aug-17 DroID_v2017_08 - - - - - - "aging defective,recessive" "lamina,medulla,adult brain,retina,glial cell,neuron,neuropil,embryonic/larval brain" FBgn0065517 l(2)SH1141 lethal (2) SH1141 http://flybase.org/reports/FBgn0065517 gene - - - "l(2)SH1141, l(2)SH2 1141" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261595 M(2)50E Minute (2) 50E http://flybase.org/reports/FBgn0261595 gene - - - M(2)50E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083291 E(smoDN)2038 Enhancer of smoDN 2038 http://flybase.org/reports/FBgn0083291 gene - - - E(smoDN)2038 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038893 Archease Archease http://flybase.org/reports/FBgn0038893 protein_coding_gene - "positive regulation of axon regeneration ; GO:0048680 | inferred from mutant phenotype tRNA splicing, via endonucleolytic cleavage and ligation ; GO:0006388 | inferred from biological aspect of ancestor with PANTHER:PTN000293690 neurogenesis ; GO:0022008 | inferred from mutant phenotype" tRNA-splicing ligase complex ; GO:0072669 | inferred from biological aspect of ancestor with PANTHER:PTN000293690 "BcDNA:SD28072, Archease, CG6353" "IPR002804:Archease, IPR023572:Archease domain" CG6353 11-Aug-17 DroID_v2017_08 Drer\zbtb8os - Cele\arch-1 Xtro\zbtb8os Mmus\Zbtb8os Hsap\ZBTB8OS "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0032163 TbCMF46 TbCMF46 http://flybase.org/reports/FBgn0032163 protein_coding_gene - - cilium ; GO:0005929 | colocalizes_with inferred from direct assay "CT32363, mel CG13125, TbCMF46, CG13125" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG13125 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-267j14.7, Drer\si:ch211-103e16.5, Drer\drc3, Drer\lrrc9, Drer\ppp1r7, Drer\lrriq1, Drer\lrrc23, Drer\lrguk, Drer\lrrcc1, Drer\LOC101885127, Drer\cep97, Drer\lrrc61, Drer\lrrc6" "Scer\NUD1, Scer\SDS22" "Cele\dct-3, Cele\K10D2.8" "Xtro\lrrc23, Xtro\drc3, Xtro\cep97, Xtro\lrrcc1, Xtro\lrrc6, Xtro\lrrc56, Xtro\lrrc49, Xtro\dnal1, Xtro\lrrc9, Xtro\ppp1r7" "Mmus\Cntrl, Mmus\Lrrc46, Mmus\Lrrc43, Mmus\Lrguk, Mmus\Lrrc49, Mmus\Lrrc56, Mmus\Lrrc23, Mmus\Dnal1, Mmus\Cep97, Mmus\Lrriq3, Mmus\Lrrc61, Mmus\Ppp1r7, Mmus\Lrrc9, Mmus\Lrrcc1, Mmus\Lrrc6, Mmus\Lrriq1, Mmus\Lrrc48" "Hsap\LRGUK, Hsap\DNAL1, Hsap\LRRC6, Hsap\LRRC61, Hsap\LRRIQ3, Hsap\DRC3, Hsap\LRRIQ1, Hsap\LRRC46, Hsap\LRRC23, Hsap\CNTRL, Hsap\LRRC43, Hsap\CEP97, Hsap\LRRC56, Hsap\PPP1R7, Hsap\LRRC49, Hsap\LRRCC1" viable FBgn0267319 CR45755 - http://flybase.org/reports/FBgn0267319 non_protein_coding_gene - - - CR45755 - CR45755 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266559 EP2083 - http://flybase.org/reports/FBgn0266559 gene - - - EP2083 - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval salivary gland FBgn0010701 l(2)s4989 lethal (2) s4989 http://flybase.org/reports/FBgn0010701 - gene - - - l(2)s4989 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262008 CG42826 - http://flybase.org/reports/FBgn0262008 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 "CG42826, CG6640" "IPR020846:Major facilitator superfamily domain, IPR005828:Major facilitator, sugar transporter-like" CG42826 11-Aug-17 DroID_v2017_08 "Drer\slc2a6, Drer\slc2a13b, Drer\slc2a12, Drer\LOC101882338, Drer\slc2a8, Drer\slc2a10" "Scer\AZR1, Scer\ITR2, Scer\ITR1, Scer\VBA5, Scer\VBA3, Scer\HXT3, Scer\GEX2, Scer\MPH2, Scer\ENB1, Scer\YMR279C, Scer\HXT10, Scer\HXT11, Scer\HXT15, Scer\GEX1, Scer\HXT17, Scer\HXT9, Scer\YDR387C, Scer\VBA2, Scer\MAL31, Scer\MPH3, Scer\STL1, Scer\YDL199C, Scer\HXT7, Scer\HXT6, Scer\GAL2, Scer\HXT4, Scer\HXT2, Scer\ATR1, Scer\VBA4, Scer\HXT16, Scer\YFL040W, Scer\HXT13, Scer\HXT5, Scer\SNF3, Scer\VBA1, Scer\RGT2, Scer\HXT8, Scer\MAL11, Scer\SGE1, Scer\HXT1, Scer\HXT14" - "Xtro\slc2a6, Xtro\slc2a12, Xtro\slc2a8, Xtro\slc2a10" "Mmus\Slc2a10, Mmus\Slc2a12, Mmus\Slc2a6, Mmus\Slc2a8, Mmus\Slc2a13" "Hsap\SLC2A10, Hsap\SLC2A12, Hsap\SLC2A13, Hsap\SLC2A6, Hsap\SLC2A8" FBgn0085614 CG41323 - http://flybase.org/reports/FBgn0085614 protein_coding_gene - - - CG41323 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013308 Odc2 Ornithine decarboxylase 2 http://flybase.org/reports/FBgn0013308 FBgn0002984 protein_coding_gene ornithine decarboxylase activity ; GO:0004586 | inferred from biological aspect of ancestor with PANTHER:PTN000159726 putrescine biosynthetic process from ornithine ; GO:0033387 | inferred from biological aspect of ancestor with PANTHER:PTN000159726 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000159726 "dodc2, CG8719, Odc2" "IPR000183:Ornithine/DAP/Arg decarboxylase, IPR002433:Ornithine decarboxylase, IPR009006:Alanine racemase/group IV decarboxylase, C-terminal, IPR029066:PLP-binding barrel, IPR022643:Orn/DAP/Arg decarboxylase 2, C-terminal, IPR022644:Orn/DAP/Arg decarboxylase 2, N-terminal, IPR022653:Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site" CG8719 11-Aug-17 DroID_v2017_08 "Drer\odc1, Drer\azin1b, Drer\azin1a" Scer\SPE1 Cele\odc-1 "Xtro\azin2, Xtro\azin1, Xtro\odc1" "Mmus\Azin1, Mmus\Gm853, Mmus\Odc1, Mmus\Azin2" "Hsap\AZIN2, Hsap\AZIN1, Hsap\ODC1" viable FBgn0265202 CR44262 - http://flybase.org/reports/FBgn0265202 non_protein_coding_gene - - - CR44262 - CR44262 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259961 CG42471 - http://flybase.org/reports/FBgn0259961 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42471 - CG42471 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011289 TfIIA-L Transcription factor IIA L http://flybase.org/reports/FBgn0011289 - protein_coding_gene "RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly ; GO:0001129 | inferred from physical interaction with Tbp TFIID-class transcription factor binding ; GO:0001094 | inferred from physical interaction with Taf4 RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly ; GO:0001128 | contributes_to inferred from physical interaction with TfIIA-S TBP-class protein binding ; GO:0017025 | inferred from physical interaction with Tbp" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with SGD:S000005720 nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIIA complex ; GO:0005672 | inferred from direct assay transcription factor TFIIA complex ; GO:0005672 | inferred from sequence or structural similarity with HGNC:4646 inferred from sequence or structural similarity with SGD:S000005720 "CT18631, TFIIA, CG5930, dTFIIA, TFIIA-L, TfIIA-L, tfiia-l, TFIIAL" "IPR004855:Transcription factor IIA, alpha/beta subunit, IPR009083:Transcription factor IIA, helical, IPR009088:Transcription factor IIA, beta-barrel" CG5930 11-Aug-17 DroID_v2017_08 "Drer\ston1, Drer\ston2, Drer\gtf2a1l, Drer\gtf2a1" Scer\TOA1 "Cele\unc-41, Cele\pqn-51" "Xtro\gtf2a1, Xtro\gtf2a1l" "Mmus\Ston2, Mmus\Gtf2a1l, Mmus\Ston1, Mmus\Gtf2a1" "Hsap\STON1-GTF2A1L, Hsap\STON2, Hsap\GTF2A1, Hsap\STON1, Hsap\GTF2A1L" "viable,fertile" DRSC16882 EK -0.674354735 0.593174026 -1.332734098 1.530427732 1.267506297 2.346933359 FBgn0028135 l(3)S050407a lethal (3) S050407a http://flybase.org/reports/FBgn0028135 gene - - - "504/7, 0504/07, l(3)S050407a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030956 CG18259 - http://flybase.org/reports/FBgn0030956 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 - - CG18259 IPR000504:RNA recognition motif domain CG18259 11-Aug-17 DroID_v2017_08 "Drer\alyref, Drer\poldip3" Scer\YRA1 "Cele\aly-1, Cele\aly-2" "Xtro\alyref, Xtro\poldip3" "Mmus\Alyref2, Mmus\Gm4302, Mmus\Gm21304, Mmus\Gm4303, Mmus\Gm4305, Mmus\Alyref, Mmus\Gm4312, Mmus\Gm8764, Mmus\Gm4307, Mmus\Poldip3" "Hsap\ALYREF, Hsap\POLDIP3" FBgn0019755 l(1)75B5 lethal (1) 75B5 http://flybase.org/reports/FBgn0019755 - gene - - - l(1)75B5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020640 Lcp65Ae Lcp65Ae http://flybase.org/reports/FBgn0020640 FBgn0035683 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence or structural similarity structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG10529, DMLCP65e, Lcp-e, DCP6, Lcp65Ae, DmelLcp65Ae" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG10529 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\F44F1.4, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " larval stage , pupal stage | 7-13 hr , embryonic stage " viable DRSC11212 E -0.900860278 -0.75881763 0.315817261 1.611122555 -0.135863798 0.286456692 FBgn0015848 anon-10Ca anon-10Ca http://flybase.org/reports/FBgn0015848 - gene - - - anon-10Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015988 l(2)PC4-R lethal (2) PC4-R http://flybase.org/reports/FBgn0015988 - gene - - - l(2)PC4-R - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024945 NitFhit Nitrilase and fragile histidine triad fusion protein http://flybase.org/reports/FBgn0024945 - protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from electronic annotation with InterPro:IPR003010 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | traceable author statement bis(5'-adenosyl)-triphosphatase activity ; GO:0047710 | inferred from direct assay" nucleobase-containing compound metabolic process ; GO:0006139 | inferred from direct assay - "CG7067, NitFhit" "IPR001310:Histidine triad (HIT) protein, IPR003010:Carbon-nitrogen hydrolase, IPR011146:HIT-like domain, IPR019808:Histidine triad, conserved site" CG7067 11-Aug-17 DroID_v2017_08 "Drer\fhit, Drer\nit1, Drer\nit2" "Scer\HNT2, Scer\NIT3, Scer\NIT2" Cele\nft-1 "Xtro\nit1, Xtro\fhit" "Mmus\Fhit, Mmus\Nit1, Mmus\Nit2" "Hsap\FHIT, Hsap\NIT1, Hsap\NIT2" " embryonic stage && adult stage , embryonic stage "

ubiquitous viable FBgn0264269 CR43769 - http://flybase.org/reports/FBgn0264269 non_protein_coding_gene - - - "CR43769, lincRNA.90" - CR43769 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026869 Thd1 Thd1 http://flybase.org/reports/FBgn0026869 - protein_coding_gene uracil DNA N-glycosylase activity ; GO:0004844 | inferred from biological aspect of ancestor with PANTHER:PTN000255408 double-stranded DNA binding ; GO:0003690 | inferred from direct assay pyrimidine-specific mismatch base pair DNA N-glycosylase activity ; GO:0008263 | inferred from direct assay "mismatch repair ; GO:0006298 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype base-excision repair, AP site formation ; GO:0006285 | inferred from biological aspect of ancestor with PANTHER:PTN000255408" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000952417 "G/T-mismatch-specific-thymine-DNA-glycosylase, CG1981, Thd1, 1981" "IPR017956:AT hook, DNA-binding motif, IPR005122:Uracil-DNA glycosylase-like, IPR015637:G/U mismatch-specific DNA glycosylase" CG1981 11-Aug-17 DroID_v2017_08 "Drer\tdg.1, Drer\tdg.2" - - Xtro\tdg Mmus\Tdg Hsap\TDG viable DRSC17169 K -0.28320226 0.293171755 -0.071027591 0.110707399 1.084548863 1.81377038 FBgn0036843 Sfxn2 Sideroflexin 2 http://flybase.org/reports/FBgn0036843 protein_coding_gene ion transmembrane transporter activity ; GO:0015075 | inferred from electronic annotation with InterPro:IPR004686 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004686 ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR004686 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR004686 "CG6812, SFXN3, Sfxn2" IPR004686:Tricarboxylate/iron carrier CG6812 11-Aug-17 DroID_v2017_08 "Drer\sfxn1, Drer\sfxn2, Drer\sfxn3, Drer\sfxn4, Drer\sfxn5b, Drer\sfxn5a" Scer\FSF1 "Cele\sfxn-1.2, Cele\sfxn-2, Cele\sfxn-1.4, Cele\sfxn-1.3, Cele\sfxn-1.5, Cele\sfxn-5, Cele\sfxn-1.1" "Xtro\sfxn1, Xtro\sfxn5, Xtro\sfxn3, Xtro\sfxn2" "Mmus\Sfxn1, Mmus\Sfxn3, Mmus\Sfxn4, Mmus\Sfxn2, Mmus\Sfxn5" "Hsap\SFXN1, Hsap\SFXN5, Hsap\SFXN3, Hsap\SFXN4, Hsap\SFXN2" viable FBgn0069321 X-164-5 X-164-5 http://flybase.org/reports/FBgn0069321 gene - - - X-164-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024989 CG3777 - http://flybase.org/reports/FBgn0024989 FBgn0025695 protein_coding_gene - - - "EG:125H10.1, CK01670, BEST:CK01670, CG3777" - CG3777 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC18489 K 0.312320409 1.183998387 1.234336032 1.203018206 -1.599148653 -0.350455827 FBgn0266086 CR44828 - http://flybase.org/reports/FBgn0266086 non_protein_coding_gene - - - CR44828 - CR44828 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065194 l(2)SH2325 lethal (2) SH2325 http://flybase.org/reports/FBgn0065194 gene - - - "l(2)SH2325, l(2)SH2 2325" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0054003 NimB3 Nimrod B3 http://flybase.org/reports/FBgn0054003 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with UniProtKB:Q1HAY7 extracellular region ; GO:0005576 | inferred from sequence model "BP1035, CG16882, CG34003, NimB3, nimB3" - CG34003 11-Aug-17 DroID_v2017_08 "Drer\scarf1, Drer\dkk2, Drer\dkk1a, Drer\tnfaip6, Drer\megf11, Drer\megf6a, Drer\megf10, Drer\megf6b, Drer\zgc:158328, Drer\ccbe1, Drer\esm1, Drer\pear1" - - "Xtro\tnfaip6, Xtro\megf11, Xtro\stab2" "Mmus\Esm1, Mmus\Stab1, Mmus\Tnfaip6, Mmus\Megf10, Mmus\Megf6, Mmus\Dkk2, Mmus\Dkk3, Mmus\Pear1, Mmus\Megf11, Mmus\Scarf1, Mmus\Egfem1" "Hsap\DKK2, Hsap\MEGF11, Hsap\PEAR1, Hsap\SCARF1, Hsap\MEGF6, Hsap\MEGF10, Hsap\SCARF2, Hsap\TNFAIP6" FBgn0013275 Hsp70Aa Heat-shock-protein-70Aa http://flybase.org/reports/FBgn0013275 "FBgn0001231, FBgn0051366" protein_coding_gene - response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "Hsp70, Hsp-70Aa, hsp70, HSP70, hsp 70, hsp70A, 87A, Hsp70A, hsp-70, hsp70(87A), hsp70Aa, Hsp 70, dhsp70, hs70, hsp70 87A, CG31366, Hsp70Aa, Hsp-70, hsp70a, Hsp70a, dHsp70, dhsp70Aa, hsp70 Aa, Dm-hsp70, DmHSP70AA" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG31366 11-Aug-17 DroID_v2017_08 "Drer\hspa5, Drer\si:ch211-199o1.2, Drer\hsp70.1, Drer\hspa13, Drer\hspa12b, Drer\hspa14, Drer\si:dkey-4p15.3, Drer\hspa8, Drer\hsc70, Drer\hspa12a, Drer\hsp70l, Drer\nckap1, Drer\hsp70.2" "Scer\SSA4, Scer\SSA3, Scer\SSQ1, Scer\SSA1, Scer\SSB1, Scer\SSZ1, Scer\SSB2, Scer\SSA2, Scer\KAR2" "Cele\hsp-4, Cele\hsp-3, Cele\F11F1.1, Cele\hsp-70, Cele\F44E5.4, Cele\gex-3, Cele\F44E5.5, Cele\hsp-1" "Xtro\hspa13, Xtro\hspa2, Xtro\hsp70, Xtro\hspa12b, Xtro\hspa1a, Xtro\nckap1l, Xtro\hspa5, Xtro\hspa1l, Xtro\hspa8, Xtro\hspa14, Xtro\hspa1b, Xtro\nckap1" "Mmus\Hspa12b, Mmus\Hspa1l, Mmus\Nckap1l, Mmus\Hspa1b, Mmus\Hspa14, Mmus\Nckap1, Mmus\Hspa12a, Mmus\Hspa5, Mmus\Hspa8, Mmus\Hspa13, Mmus\Hspa1a, Mmus\Hspa2" "Hsap\HSPA2, Hsap\HSPA12A, Hsap\HSPA1B, Hsap\NCKAP1L, Hsap\HSPA12B, Hsap\HSPA1A, Hsap\HSPA6, Hsap\HSPA13, Hsap\NCKAP1, Hsap\HSPA8, Hsap\HSPA1L, Hsap\HSPA14, Hsap\HSPA5" "lethal,viable,fertile" DRSC21246 IEK 0.234830516 -2.273098897 -1.685379565 -1.340837156 0.087446517 1.996683836 FBgn0034795 MED23 Mediator complex subunit 23 http://flybase.org/reports/FBgn0034795 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with UniProtKB:Q9W5P1 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:Q9W5P1 mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from sequence or structural similarity with UniProtKB:Q9W5P1 "Trap150, Med23, Trap150beta, CG3695, Gal11/SUR2, dSUR2, dTRAP150beta, MED23" "IPR011990:Tetratricopeptide-like helical domain, IPR021629:Mediator complex, subunit Med23" CG3695 11-Aug-17 DroID_v2017_08 Drer\med23 - Cele\sur-2 Xtro\med23 Mmus\Med23 Hsap\MED23 viable FBgn0263132 Cht6 Chitinase 6 http://flybase.org/reports/FBgn0263132 protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR001579 chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557" "chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG2989, CG43374, Cht6, CT5624, CG15314, CG15313, DmCht6" "IPR029070:Chitinase insertion domain, IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR002557:Chitin binding domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily" CG43374 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-226m16.2, Drer\srl, Drer\chia.1, Drer\chia.3, Drer\chia.2, Drer\chia.6, Drer\ovgp1, Drer\chia.5" "Scer\CTS2, Scer\CTS1" "Cele\chil-11, Cele\chil-7, Cele\chil-4, Cele\cht-2, Cele\cht-4, Cele\cht-1" "Xtro\chia, Xtro\srl, Xtro\LOC548945, Xtro\ctbs, Xtro\chit1" "Mmus\Chil5, Mmus\Chil6, Mmus\Chil3, Mmus\Chit1, Mmus\Chil4, Mmus\Chia1, Mmus\Ovgp1, Mmus\Chil1, Mmus\Srl, Mmus\Ctbs" "Hsap\SRL, Hsap\OVGP1, Hsap\CHIT1, Hsap\CTBS, Hsap\CHI3L1, Hsap\CHI3L2, Hsap\CHIA" FBgn0044874 E(Mer)IIIa E(Mer)IIIa http://flybase.org/reports/FBgn0044874 gene - - - "Group IIIa, E(Mer)IIIa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,visible,dominant" wing vein L5 FBgn0060457 l(3)S117913 lethal (3) S117913 http://flybase.org/reports/FBgn0060457 gene - - - "1179/13, l(3)S117913" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0032480 Edem2 "ER degradation enhancer, mannosidase alpha-like 2" http://flybase.org/reports/FBgn0032480 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001382 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 unfolded protein binding ; GO:0051082 | inferred from physical interaction with ninaE mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from sequence model" N-glycan processing ; GO:0006491 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from genetic interaction with ninaE glycoprotein ERAD pathway ; GO:0097466 | inferred from biological aspect of ancestor with PANTHER:PTN000201758 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from genetic interaction with ninaE membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001382 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 "Edem2, EDEM2, CG5682, edem2" "IPR001382:Glycoside hydrolase family 47, IPR003137:PA domain" CG5682 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-282j22.3, Drer\edem1, Drer\edem3, Drer\edem2" Scer\MNL1 "Cele\C47E12.3, Cele\F10C2.5, Cele\ZC506.1" "Xtro\edem2, Xtro\edem3, Xtro\edem1" "Mmus\Edem3, Mmus\Edem1, Mmus\Edem2" "Hsap\EDEM1, Hsap\EDEM2, Hsap\EDEM3" viable DRSC02877 E 0.409168354 0.287296474 -2.375067372 0.798823179 0.139725863 -0.86745841 FBgn0051413 CG31413 - http://flybase.org/reports/FBgn0051413 protein_coding_gene flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR017905 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 extracellular space ; GO:0005615 | inferred from sequence model integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 "CG10299, CG31413" "IPR012336:Thioredoxin-like fold, IPR017905:ERV/ALR sulfhydryl oxidase domain, IPR013766:Thioredoxin domain" CG31413 11-Aug-17 DroID_v2017_08 "Drer\qsox1, Drer\qsox2" - "Cele\F47B7.2, Cele\T10H10.2, Cele\F35G2.1" "Xtro\qsox2, Xtro\qsox1" "Mmus\Qsox1, Mmus\Qsox2" "Hsap\QSOX1, Hsap\QSOX2" FBgn0013445 fout fade out http://flybase.org/reports/FBgn0013445 - gene molecular_function ; GO:0003674 | no biological data available grooming behavior ; GO:0007625 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fout - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive" FBgn0003969 vap vacuolar peduncle http://flybase.org/reports/FBgn0003969 FBgn0020383 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from direct assay negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 mushroom body development ; GO:0016319 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay regulation of growth ; GO:0040008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay intrinsic component of the cytoplasmic side of the plasma membrane ; GO:0031235 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 "RAS-GAP, RasGAP, RasGap, D-RasGAP, rasGap, CG9209, vap, RasGAP/Vap, p120RasGAP, FBpp0073946" "IPR000008:C2 domain, IPR000980:SH2 domain, IPR001452:SH3 domain, IPR001849:Pleckstrin homology domain, IPR001936:Ras GTPase-activating protein, IPR008936:Rho GTPase activation protein, IPR011993:PH domain-like, IPR023152:Ras GTPase-activating protein, conserved site, IPR028554:Ras GTPase-activating protein 1" CG9209 11-Aug-17 DroID_v2017_08 "Drer\dab2ipa, Drer\syngap1b, Drer\rasa1a, Drer\syngap1a, Drer\rasal2, Drer\dab2ipb, Drer\rasa1b, Drer\rasal3" "Scer\BUD2, Scer\IRA1, Scer\IRA2" Cele\gap-3 "Xtro\syngap1, Xtro\rasal2, Xtro\rasal3, Xtro\rasa1" "Mmus\Dab2ip, Mmus\Rasa1, Mmus\Rasal3, Mmus\Syngap1, Mmus\Rasal2" "Hsap\SYNGAP1, Hsap\RASAL2, Hsap\RASAL3, Hsap\RASA1, Hsap\DAB2IP" embryonic stage -- adult stage "viable,fertile,short lived,recessive,neuroanatomy defective,visible" "adult brain,ellipsoid body,nodulus,neuron & adult brain,lysosome & neuron & adult brain,autophagic vacuole & neuron & adult brain,optic lobe,wing" FBgn0082345 HM501 HM501 http://flybase.org/reports/FBgn0082345 gene - - - HM501 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085821 CR41612 - http://flybase.org/reports/FBgn0085821 non_protein_coding_gene - - - CR41612 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085217 CG34188 - http://flybase.org/reports/FBgn0085217 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34188 - CG34188 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036871 CG14096 - http://flybase.org/reports/FBgn0036871 protein_coding_gene - - - CG14096 - CG14096 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001585 l(1)carot2 lethal (1) carot2 http://flybase.org/reports/FBgn0001585 - gene - - - "l(1)5, l(1)carot2" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034427 CG10474 - http://flybase.org/reports/FBgn0034427 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000246 - - CG10474 "IPR000246:Peptidase T2, asparaginase 2, IPR029055:Nucleophile aminohydrolases, N-terminal" CG10474 11-Aug-17 DroID_v2017_08 "Drer\zgc:153169, Drer\aga" - Cele\R04B3.2 Xtro\aga Mmus\Aga Hsap\AGA viable DRSC05993 K -0.310741477 1.024861685 -0.080854886 0.768602311 0.315750793 1.652017327 FBgn0263538 mir-4965 mir-4965 stem loop http://flybase.org/reports/FBgn0263538 miRNA_gene - - - "mir-4965, dme-mir-4965, CR43523" - CR43523 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037230 CG9780 - http://flybase.org/reports/FBgn0037230 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753" - CG9780 "IPR000718:Peptidase M13, IPR024079:Metallopeptidase, catalytic domain, IPR008753:Peptidase M13, N-terminal domain" CG9780 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\mmel1, Drer\ece2b, Drer\phex" - "Cele\nep-12, Cele\nep-18, Cele\nep-17, Cele\nep-5, Cele\nep-16, Cele\nep-26" "Xtro\ece2, Xtro\ecel1, Xtro\mmel1, Xtro\ece1" "Mmus\Ece1, Mmus\Kel, Mmus\Mmel1, Mmus\Ece2, Mmus\Ecel1, Mmus\Phex, Mmus\Mme" "Hsap\MME, Hsap\ECE1, Hsap\KEL, Hsap\PHEX, Hsap\MMEL1, Hsap\ECEL1, Hsap\ECE2" viable DRSC12333 I 2.158099171 0.690104653 -0.087531775 0.332305369 -0.219201597 0.651107935 FBgn0029729 CG12682 - http://flybase.org/reports/FBgn0029729 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12682 IPR031732:Protein of unknown function DUF4729 CG12682 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005066 fs(2)OW206 female sterile (2) OW206 http://flybase.org/reports/FBgn0005066 - gene - - - fs(2)OW206 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020446 E-1a E-1a http://flybase.org/reports/FBgn0020446 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available E-1a - - 11-Aug-17 DroID_v2017_08 - - - - - - somatic muscle FBgn0002408 l(3)99Di lethal (3) 99Di http://flybase.org/reports/FBgn0002408 - gene - - - l(3)99Di - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0283458 EC3-13 Enhancer of CCT 3-13 http://flybase.org/reports/FBgn0283458 gene - - - EC3-13 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066131 E(sda)B E(sda)B http://flybase.org/reports/FBgn0066131 gene - - - "E(sda)B, Line B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263582 CR43607 - http://flybase.org/reports/FBgn0263582 non_protein_coding_gene - - - CR43607 - CR43607 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028218 l(3)S007934 lethal (3) S007934 http://flybase.org/reports/FBgn0028218 gene - - - "l(3)s007934, 1175/05, 0363/02, 0079/34, l(3)S007934" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264279 Su(Mir)1A4-1 - http://flybase.org/reports/FBgn0264279 gene - - - Su(Mir)1A4-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001578 l(1)air16 lethal aberrant immune response 16 http://flybase.org/reports/FBgn0001578 - gene - - - "air16, l(1)air16" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,melanotic mass phenotype,lethal,polyphasic" "embryonic/larval brain,melanotic mass,embryonic/larval lymph gland,embryonic/larval hindgut,ring gland,gastric caecum,embryonic/larval salivary gland,garland cell" FBgn0035703 CG8270 - http://flybase.org/reports/FBgn0035703 protein_coding_gene - - - CG8270 "IPR009755:Colon cancer-associated Mic1-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG8270 11-Aug-17 DroID_v2017_08 Drer\zgc:101800 - Cele\Y50D4A.4 Xtro\c18orf8 Mmus\3110002H16Rik Hsap\C18orf8 viable FBgn0082681 E(ftz)3201 E(ftz)3201 http://flybase.org/reports/FBgn0082681 gene - - - "3201, E(ftz)3201" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042083 CG3267 - http://flybase.org/reports/FBgn0042083 protein_coding_gene methylcrotonoyl-CoA carboxylase activity ; GO:0004485 | inferred from sequence or structural similarity with UniProtKB:Q9HCC0 leucine metabolic process ; GO:0006551 | inferred from sequence or structural similarity with UniProtKB:Q9HCC0 regulation of eclosion ; GO:0007563 | inferred from mutant phenotype mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q9HCC0 "FBgn0042083, l(2)4524, CG3267, MCCC2_DROME" "IPR011762:Acetyl-coenzyme A carboxyltransferase, N-terminal, IPR011763:Acetyl-coenzyme A carboxyltransferase, C-terminal, IPR034733:Acetyl-CoA carboxylase, IPR029045:ClpP/crotonase-like domain" CG3267 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-198n5.11, Drer\pccb, Drer\mccc2" - "Cele\F02A9.4, Cele\pccb-1" "Xtro\mccc2, Xtro\LOC100497391, Xtro\pccb" "Mmus\Mccc2, Mmus\Pccb" "Hsap\PCCB, Hsap\MCCC2" "partially lethal - majority die,lethal,recessive,viable" FBgn0024218 l(2)39Ea lethal (2) 39Ea http://flybase.org/reports/FBgn0024218 - gene - - - l(2)39Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266956 CR45407 - http://flybase.org/reports/FBgn0266956 non_protein_coding_gene - - - CR45407 - CR45407 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058313 CG40313 - http://flybase.org/reports/FBgn0058313 protein_coding_gene - - - CG40313 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015914 bk27 bk27 http://flybase.org/reports/FBgn0015914 - gene - - - bk27 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070057 11 11 http://flybase.org/reports/FBgn0070057 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "#1, 11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001270 irreA irregular optic chiasma A http://flybase.org/reports/FBgn0001270 - gene - - - irreA - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037541 CG2747 - http://flybase.org/reports/FBgn0037541 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG2747 "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG2747 11-Aug-17 DroID_v2017_08 "Drer\heatr5b, Drer\heatr5a" Scer\LAA1 Cele\soap-1 "Xtro\heatr5a, Xtro\heatr5b" "Mmus\Heatr5a, Mmus\Heatr5b" "Hsap\HEATR5B, Hsap\HEATR5A" "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0060439 l(3)S124802a lethal (3) S124802a http://flybase.org/reports/FBgn0060439 gene - - - "1248/02, l(3)S124802a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065898 l(2)SH0204 lethal (2) SH0204 http://flybase.org/reports/FBgn0065898 gene - - - "l(2)SH0204, l(2)SH2 0204" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259149 CG42264 - http://flybase.org/reports/FBgn0259149 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "CG42264, CG15768, CG15769" "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR003146:Carboxypeptidase, activation peptide, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain" CG42264 11-Aug-17 DroID_v2017_08 "Drer\cpo, Drer\cpb2, Drer\cpa6, Drer\cpa4, Drer\cpb1, Drer\cpa5, Drer\cpa2, Drer\cpa1" Scer\ECM14 "Cele\Y18H1A.9, Cele\T06A4.1, Cele\Y47G6A.19, Cele\ZC434.9, Cele\W01A8.6, Cele\suro-1, Cele\F02D8.4, Cele\Y59C2A.1, Cele\T06A4.3" "Xtro\cpb2, Xtro\cpa1, Xtro\cpb1, Xtro\cpo, Xtro\cpa3" "Mmus\Cpb2, Mmus\Cpa4, Mmus\Cpa1, Mmus\Cpa2, Mmus\Cpa5, Mmus\Cpb1, Mmus\Cpa3, Mmus\Cpa6" "Hsap\CPA6, Hsap\CPA1, Hsap\CPA2, Hsap\CPB2, Hsap\CPB1, Hsap\CPA5, Hsap\CPA4, Hsap\CPA3, Hsap\CPO" FBgn0028747 E(E2f)2B E(E2f)2B http://flybase.org/reports/FBgn0028747 gene - - - "E(E2F)2B, E(E2f)2B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065276 l(2)SH2046 lethal (2) SH2046 http://flybase.org/reports/FBgn0065276 gene - - - "l(2)SH2046, l(2)SH2 2046" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014346 ms(2)916 male sterile (2) 916 http://flybase.org/reports/FBgn0014346 - gene - - - ms(2)916 - - 11-Aug-17 DroID_v2017_08 - - - - - - testis FBgn0038462 CG17556 - http://flybase.org/reports/FBgn0038462 protein_coding_gene - protein folding in endoplasmic reticulum ; GO:0034975 | inferred from biological aspect of ancestor with PANTHER:PTN000298542 microtubule associated complex ; GO:0005875 | inferred from direct assay ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN000298542 CG17556 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG17556 11-Aug-17 DroID_v2017_08 Drer\emc2 Scer\EMC2 Cele\emc-2 Xtro\emc2 Mmus\Emc2 Hsap\EMC2 FBgn0002133 l(2)K208 lethal (2) K208 http://flybase.org/reports/FBgn0002133 - gene - - - l(2)K208 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0083242 EP1244 EP1244 http://flybase.org/reports/FBgn0083242 gene - - - EP1244 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030792 CG4789 - http://flybase.org/reports/FBgn0030792 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000001722 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4789, Q9VXA9" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily" CG4789 11-Aug-17 DroID_v2017_08 Drer\rabl3 Scer\YPT10 Cele\Y116A8C.10 Xtro\rabl3 Mmus\Rabl3 Hsap\RABL3 viable FBgn0020429 GluRIIB Glutamate receptor IIB http://flybase.org/reports/FBgn0020429 - protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity with HGNC:4579 glutamate-gated calcium ion channel activity ; GO:0022849 | inferred from direct assay ionotropic glutamate receptor activity ; GO:0004970 | inferred from mutant phenotype "regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from direct assay regulation of synaptic activity ; GO:0060025 | inferred from sequence or structural similarity with GluRIIA synaptic transmission, glutamatergic ; GO:0035249 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with GluRIIA postsynaptic membrane ; GO:0045211 | colocalizes_with inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay ionotropic glutamate receptor complex ; GO:0008328 | inferred from mutant phenotype muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay "dglurIIB, dGluRIIB, DGluRIIB, glurIIB, DGluR-IIB, GluRIIb, DGluIIB, CG7234, Glu-RIIB, GluRIIB, DmelGluRIIB" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG7234 11-Aug-17 DroID_v2017_08 "Drer\grik5, Drer\grik1a, Drer\si:ch211-251b21.1, Drer\LOC100334689, Drer\grik4, Drer\LOC100331381, Drer\grik1b, Drer\si:dkey-183j2.10" - "Cele\glr-3, Cele\glr-8, Cele\glr-5, Cele\glr-6, Cele\glr-4" "Xtro\grik5, Xtro\grik4, Xtro\grik1" "Mmus\Grik1, Mmus\Grik2, Mmus\Grik3, Mmus\Grik5, Mmus\Grin3a, Mmus\Grik4" "Hsap\GRIK4, Hsap\GRIK2, Hsap\GRIK1, Hsap\GRIN3A, Hsap\GRIK5, Hsap\GRIK3" embryonic stage | stage 17 larval neuromuscular junction

"wild-type,neurophysiology defective,neuroanatomy defective,viable" "neuromuscular junction,neuromuscular junction | larval stage,neuromuscular junction | larval stageMhc.PW,neuromuscular junctionMhc.PW,neuromuscular junctionhow-24B" FBgn0264516 CG43915 - http://flybase.org/reports/FBgn0264516 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from sequence model CG43915 - CG43915 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034776 CG13527 - http://flybase.org/reports/FBgn0034776 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH182, CG13527" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG13527 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020376 Sr-CIII "Scavenger receptor class C, type III" http://flybase.org/reports/FBgn0020376 FBgn0051962 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000998 "dSR-CIII, CG31962, Sr-CIII, SR-CIII" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR000436:Sushi/SCR/CCP domain, IPR000998:MAM domain" CG31962 11-Aug-17 DroID_v2017_08 "Drer\wu:fb63a08, Drer\mamdc1, Drer\malrd1, Drer\si:ch73-40a17.3" - - - "Mmus\Mdga2, Mmus\Mep1b, Mmus\Malrd1, Mmus\Cd55b, Mmus\Mdga1" "Hsap\MEP1B, Hsap\MDGA2, Hsap\MDGA1, Hsap\MALRD1" "viable,tumorigenic" DRSC22262 K -0.277835385 0.362907379 -0.03892982 0.238862749 -1.870850254 -1.181891372 FBgn0085399 CG34370 - http://flybase.org/reports/FBgn0085399 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34370, CG13499, tld-like, CT32866, CG13498, CG13497, CG30408, CG30405, CG33227, BP1037, CG34004" IPR000859:CUB domain CG34370 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0038069 CG11608 - http://flybase.org/reports/FBgn0038069 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG11608 "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG11608 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH2, Scer\YEH1, Scer\TGL1" "Cele\lipl-4, Cele\lipl-8, Cele\lipl-6, Cele\lipl-1, Cele\lipl-3, Cele\lipl-5, Cele\lipl-7, Cele\lipl-2" Xtro\lipa "Mmus\Lipo2, Mmus\Lipo1, Mmus\Lipk, Mmus\Lipm, Mmus\Lipo4, Mmus\Lipo3, Mmus\Lipa, Mmus\Lipf, Mmus\Lipn" "Hsap\LIPK, Hsap\LIPJ, Hsap\LIPF, Hsap\LIPN, Hsap\LIPM, Hsap\LIPA" viable DRSC14334 K 0.62264917 -0.03912048 0.121043963 0.1225708 -0.720828306 1.988500645 FBgn0034382 CG18609 - http://flybase.org/reports/FBgn0034382 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "CT42569, CG18609" IPR002076:ELO family CG18609 11-Aug-17 DroID_v2017_08 "Drer\elovl1b, Drer\elovl5, Drer\zgc:101858, Drer\dhrs7, Drer\elovl1a, Drer\elovl8a, Drer\elovl8b, Drer\elovl7b, Drer\hsd17b8, Drer\elovl4b, Drer\elovl7a, Drer\elovl4a, Drer\elovl2" "Scer\ELO1, Scer\ELO2, Scer\ELO3" "Cele\Y47G6A.22, Cele\C06E4.3, Cele\ZK829.1, Cele\elo-4, Cele\F28H7.2, Cele\dhs-25, Cele\dhs-14, Cele\F26D2.15, Cele\elo-6, Cele\Y47G6A.21, Cele\elo-5, Cele\dhs-11, Cele\elo-3, Cele\F25D1.5, Cele\elo-1" "Xtro\elovl5, Xtro\elovl1, Xtro\hsd17b8, Xtro\elovl2, Xtro\elovl7, Xtro\MGC79752, Xtro\cbr4, Xtro\dhrs7" "Mmus\Elovl7, Mmus\Elovl4, Mmus\Cbr4, Mmus\Dhrs7, Mmus\Elovl2, Mmus\Elovl5, Mmus\Elovl6, Mmus\Elovl1, Mmus\H2-Ke6" "Hsap\ELOVL7, Hsap\ELOVL2, Hsap\ELOVL5, Hsap\ELOVL6, Hsap\DHRS7, Hsap\ELOVL1, Hsap\HSD17B8, Hsap\CBR4, Hsap\ELOVL4" viable FBgn0035999 CG3552 - http://flybase.org/reports/FBgn0035999 protein_coding_gene GDP-D-glucose phosphorylase activity ; GO:0080048 | inferred from biological aspect of ancestor with PANTHER:PTN000467038 glucose metabolic process ; GO:0006006 | inferred from biological aspect of ancestor with PANTHER:PTN000467038 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000467038 CG3552 "IPR011146:HIT-like domain, IPR026506:GDP-L-galactose/GDP-D-glucose phosphorylase" CG3552 11-Aug-17 DroID_v2017_08 Drer\zgc:153343 - Cele\mcp-1 Xtro\gdpgp1 Mmus\Gdpgp1 Hsap\GDPGP1 viable FBgn0082580 tym thyme http://flybase.org/reports/FBgn0082580 gene - - - tym - - 11-Aug-17 DroID_v2017_08 - - - - - - dendrite FBgn0029589 CG14810 - http://flybase.org/reports/FBgn0029589 protein_coding_gene - - - CG14810 - CG14810 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC17693 I -1.040430477 2.424301473 0.432929002 -0.483397433 -0.898744332 0.21346334 FBgn0262518 Rab8 Rab8 http://flybase.org/reports/FBgn0262518 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" sleep ; GO:0030431 | inferred from expression pattern protein localization to plasma membrane ; GO:0072659 | inferred from biological aspect of ancestor with PANTHER:PTN000635134 regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle docking involved in exocytosis ; GO:0006904 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 protein secretion ; GO:0009306 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 synapse ; GO:0045202 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 neuronal cell body ; GO:0043025 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000635134 "Rab8, rab8, dm-Rab8, Dm Rab8, AAF49101, DmRab8, CG8287, DRab8, DRAB8, Rab-r8, l(3)76BDu, O18338" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain" CG8287 11-Aug-17 DroID_v2017_08 "Drer\rab10, Drer\rab35b, Drer\zgc:162879, Drer\zgc:171927, Drer\rab12, Drer\rab13, Drer\si:dkey-16l2.16, Drer\rab44, Drer\rasef, Drer\rab1aa, Drer\LOC100535415, Drer\rab40b, Drer\rab8b, Drer\rab1ab, Drer\rab8a, Drer\rab15, Drer\rab40c" Scer\SEC4 "Cele\rab-10, Cele\rab-1, Cele\rab-35, Cele\rab-8" "Xtro\rab35, Xtro\rasef, Xtro\rab12, Xtro\rab1a, Xtro\rab8b, Xtro\rab8a, Xtro\rasef, Xtro\rab44, Xtro\rab13, Xtro\rab10, Xtro\rab35, Xtro\rab40b, Xtro\rab28, Xtro\LOC100135070, Xtro\rab15" "Mmus\Rab10, Mmus\Rab28, Mmus\Rab1b, Mmus\Rab8b, Mmus\Rab13, Mmus\Rab15, Mmus\Rab40c, Mmus\Rab12, Mmus\Rasef, Mmus\Rab40b, Mmus\Rab35, Mmus\Rab1a, Mmus\Rab44, Mmus\Rab8a" "Hsap\RAB1B, Hsap\RAB8B, Hsap\RAB13, Hsap\RAB1A, Hsap\RAB40B, Hsap\RAB8A, Hsap\RAB40A, Hsap\RAB12, Hsap\RASEF, Hsap\RAB35, Hsap\RAB15, Hsap\RAB40AL, Hsap\RAB10, Hsap\RAB28, Hsap\RAB40C" FBgn0039079 Ir94g Ionotropic receptor 94g http://flybase.org/reports/FBgn0039079 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir94g, IR94g, CG17381, DmelIR94g" - CG17381 11-Aug-17 DroID_v2017_08 - - Cele\W02A2.5 - - - viable FBgn0266688 CR45178 - http://flybase.org/reports/FBgn0266688 non_protein_coding_gene - - - CR45178 - CR45178 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001153 giantoid giantoid http://flybase.org/reports/FBgn0001153 - gene - - - "giantoid, gtd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced" adult head FBgn0084829 l(3)S023708 l(3)S023708 http://flybase.org/reports/FBgn0084829 gene - - - l(3)S023708 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086687 Desat1 Desaturase 1 http://flybase.org/reports/FBgn0086687 protein_coding_gene stearoyl-CoA 9-desaturase activity ; GO:0004768 | inferred from electronic annotation with InterPro:IPR009160 "unsaturated fatty acid biosynthetic process ; GO:0006636 | inferred from electronic annotation with InterPro:IPR009160 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015876 cuticle hydrocarbon biosynthetic process ; GO:0006723 | inferred from mutant phenotype pheromone biosynthetic process ; GO:0042811 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype response to sucrose ; GO:0009744 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype mating behavior, sex discrimination ; GO:0048047 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype regulation of lipid metabolic process ; GO:0019216 | inferred from mutant phenotype male mating behavior ; GO:0060179 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype glucose homeostasis ; GO:0042593 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009160 endoplasmic reticulum ; GO:0005783 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG5887, desat1, ds1, Fad, fad, desat, l(3)S028813, BEST:SD05462, anon-WO0118547.730, anon-WO0118547.726, Desat1" "IPR015876:Acyl-CoA desaturase, IPR005804:Fatty acid desaturase domain, IPR009160:Acyl-CoA desaturase, haem/steroid binding domain-containing" CG5887 11-Aug-17 DroID_v2017_08 "Drer\scd, Drer\scdb" Scer\OLE1 "Cele\fat-7, Cele\fat-6, Cele\fat-5" Xtro\scd "Mmus\Scd4, Mmus\Scd2, Mmus\Scd1, Mmus\Scd3" "Hsap\SCD, Hsap\SCD5" DRSC16668 IEK -0.173004436 -1.876243832 0.328621657 -3.181107084 -5.590737184 -3.234440361 FBgn0264674 CR43959 - http://flybase.org/reports/FBgn0264674 non_protein_coding_gene - - - CR43959 - CR43959 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060354 l(3)S141710a lethal (3) S141710a http://flybase.org/reports/FBgn0060354 gene - - - "1417/10, l(3)S141710a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039936 Gyf Gigyf http://flybase.org/reports/FBgn0039936 protein_coding_gene - "muscle cell cellular homeostasis ; GO:0046716 | inferred from genetic interaction with Atg1, Atg13 neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with Atg1, Atg13 regulation of autophagy ; GO:0010506 | inferred from genetic interaction with Atg1, Atg13" mitotic spindle ; GO:0072686 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "CG11148, Gyf, Q7KQM6" IPR003169:GYF domain CG11148 11-Aug-17 DroID_v2017_08 "Drer\gigfy2, Drer\gigyf1, Drer\gigyf1" "Scer\SYH1, Scer\SMY2" "Cele\C18H9.3, Cele\K11H3.8, Cele\T13G4.1, Cele\sao-1" Xtro\gigyf1 "Mmus\Gigyf1, Mmus\Gigyf2" "Hsap\GIGYF1, Hsap\GIGYF2" viable DRSC28907 K -0.005465446 -0.019092797 -0.027287401 0.043405609 2.418090207 1.828460345 FBgn0003878 tu(2)bw tumor (2) brown http://flybase.org/reports/FBgn0003878 - gene - - - "mt[A], tu(2)bw" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,viable,fertile" "thorax,head" FBgn0060662 l(3)S081610b lethal (3) S081610b http://flybase.org/reports/FBgn0060662 gene - - - "0816/10, l(3)S081610b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051578 tRNA:Pro-TGG-1-4 transfer RNA:Proline-TGG 1-4 http://flybase.org/reports/FBgn0051578 tRNA_gene CCA codon-amino acid adaptor activity ; GO:0033423 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033423 cytosol ; GO:0005829 | inferred by curator from GO:0033423 "AE002708.trna14-ProTGG, tRNA:P:TGG:AE002708-c, CR31578, chr3R.trna20-ProTGG, tRNA-Pro-TGG-1-4, tRNA:Pro-TGG-1-4, tRNA:CR31578, CCA" - CR31578 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032021 CG7781 - http://flybase.org/reports/FBgn0032021 protein_coding_gene - - - CG7781 - CG7781 11-Aug-17 DroID_v2017_08 - - "Cele\T03F6.9, Cele\K11H12.7, Cele\C15H9.9, Cele\ZK287.9, Cele\F35C5.11, Cele\F28A12.3, Cele\K11H12.6" - - - DRSC03068 K -1.0851981 -0.389909414 -0.511481237 0.317317805 -1.68037549 0.048809598 FBgn0001638 l(1)dn18 lethal (1) discs normal 18 http://flybase.org/reports/FBgn0001638 - gene - - - "l(1)d.norm.-18, l(1)dn18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0063396 Stalker2\ORF3 Stalker2 element ORF3 http://flybase.org/reports/FBgn0063396 transposable_element_gene - - - "rom\ORF3, Stalker2\ORF3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058392 CG40392 - http://flybase.org/reports/FBgn0058392 protein_coding_gene - - - CG40392 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050062 CG30062 - http://flybase.org/reports/FBgn0050062 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 - - CG30062 "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR023346:Lysozyme-like domain, IPR019799:Glycoside hydrolase, family 22, conserved site" CG30062 11-Aug-17 DroID_v2017_08 "Drer\LOC100536671, Drer\lyz, Drer\LOC100334363" - - Xtro\MGC89221 "Mmus\Lyzl1, Mmus\Lyz1, Mmus\Lalba, Mmus\Spaca3, Mmus\Spaca1, Mmus\1700016D06Rik, Mmus\Spaca5, Mmus\Lyz2, Mmus\Lyzl4, Mmus\Spaca4, Mmus\Spaca7, Mmus\9530003J23Rik, Mmus\Lyzl6" "Hsap\SPACA3, Hsap\LALBA, Hsap\LYZL1, Hsap\SPACA7, Hsap\SPACA1, Hsap\LYZL4, Hsap\LYZ, Hsap\SPACA5, Hsap\SPACA5B, Hsap\LYZL6, Hsap\LYZL2, Hsap\SPACA4" viable FBgn0062586 Mod(var)1658 Mod(var)1658 http://flybase.org/reports/FBgn0062586 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1658, Mod(var)1658" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0083989 snoRNA:Me28S-C3420b snoRNA:Me28S-C3420b http://flybase.org/reports/FBgn0083989 snoRNA_gene - - - "CR34153, snoRNA:Me28S-C3420b, Me28S-C3420b, chr2R:7715032..7715192" - CR34153 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022013 l(2)k09104 lethal (2) k09104 http://flybase.org/reports/FBgn0022013 - gene - - - l(2)k09104 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033121 Cyp6u1 Cyp6u1 http://flybase.org/reports/FBgn0033121 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "6u1, CG3567, Cyp6u1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG3567 11-Aug-17 DroID_v2017_08 "Drer\cyp3c3, Drer\cyp3c4, Drer\cyp3c1, Drer\cyp3c2, Drer\cyp3a65, Drer\tbxas1" Scer\ERG11 "Cele\cyp-13A5, Cele\cyp-25A2, Cele\cyp-13A8, Cele\cyp-13A2, Cele\cyp-13A11, Cele\cyp-25A6, Cele\cyp-44A1, Cele\cyp-13B1, Cele\cyp-13A6, Cele\cyp-13A1, Cele\cyp-25A4, Cele\cyp-13A3, Cele\cyp-13A4, Cele\cyp-13A7, Cele\cyp-13A12, Cele\cyp-13A10, Cele\cyp-43A1, Cele\cyp-25A3, Cele\cyp-13B2, Cele\cyp-25A1" "Xtro\tbxas1, Xtro\cyp3a5, Xtro\LOC100494419, Xtro\cyp3a4" "Mmus\Cyp3a11, Mmus\Cyp3a41a, Mmus\Cyp3a13, Mmus\Tbxas1, Mmus\Cyp3a57, Mmus\Cyp3a16, Mmus\Cyp3a44, Mmus\Cyp3a41b, Mmus\Cyp3a59, Mmus\Cyp3a25" "Hsap\TBXAS1, Hsap\CYP3A4, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A43" viable FBgn0038134 wntD wnt inhibitor of Dorsal http://flybase.org/reports/FBgn0038134 protein_coding_gene frizzled binding ; GO:0005109 | inferred from physical interaction with fz4 frizzled binding ; GO:0005109 | non-traceable author statement Wnt signaling pathway ; GO:0016055 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 neuron differentiation ; GO:0030182 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 Wnt signaling pathway ; GO:0016055 | non-traceable author statement pole cell migration ; GO:0007280 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype inferred from genetic interaction with dl ventral furrow formation ; GO:0007370 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 extracellular region ; GO:0005576 | inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | non-traceable author statement "CG8458, Wnt8, DWnt8, DWnt-8, wntD, WntD, wnt8, Dm DWnt8" IPR005817:Wnt CG8458 11-Aug-17 DroID_v2017_08 "Drer\wnt2, Drer\wnt11r, Drer\wnt3a, Drer\wnt10b, Drer\wnt6a, Drer\wnt6b, Drer\wnt10a, Drer\wnt5a, Drer\wnt1, Drer\wnt16, Drer\wnt7bb, Drer\wnt4b, Drer\wnt2bb, Drer\wnt9b, Drer\wnt3, Drer\wnt7ba, Drer\wnt9a, Drer\wnt7aa, Drer\wnt11, Drer\wnt4a, Drer\LOC568110, Drer\wnt8b, Drer\wnt8a, Drer\wnt2ba" - "Cele\lin-44, Cele\mom-2, Cele\cwn-1" "Xtro\wnt7b, Xtro\wnt4, Xtro\wnt16, Xtro\wnt10b, Xtro\wnt1, Xtro\wnt8a, Xtro\wnt9b, Xtro\wnt2b, Xtro\wnt8b, Xtro\wnt11, Xtro\wnt7a, Xtro\wnt5b, Xtro\wnt11r, Xtro\wnt7c, Xtro\wnt3a, Xtro\wnt9b.2" "Mmus\Wnt6, Mmus\Wnt7b, Mmus\Wnt5a, Mmus\Wnt4, Mmus\Wnt2b, Mmus\Wnt10b, Mmus\Wnt5b, Mmus\Wnt2, Mmus\Wnt16, Mmus\Wnt10a, Mmus\Wnt9b, Mmus\Wnt1, Mmus\Wnt11, Mmus\Wnt8a, Mmus\Wnt9a, Mmus\Wnt3a, Mmus\Wnt3, Mmus\Wnt7a, Mmus\Wnt8b" "Hsap\WNT16, Hsap\WNT8B, Hsap\WNT3A, Hsap\WNT10A, Hsap\WNT3, Hsap\WNT6, Hsap\WNT7A, Hsap\WNT8A, Hsap\WNT1, Hsap\WNT5A, Hsap\WNT4, Hsap\WNT2B, Hsap\WNT9B, Hsap\WNT11, Hsap\WNT7B, Hsap\WNT9A, Hsap\WNT5B, Hsap\WNT2, Hsap\WNT10B" "viable,immune response defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,maternal effect" "germline cell,embryo,ventral,ventral furrow,mesoderm" FBgn0262576 CG43116 - http://flybase.org/reports/FBgn0262576 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43116 - CG43116 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085684 CG41553 - http://flybase.org/reports/FBgn0085684 protein_coding_gene - - - CG41553 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261555 CG42673 - http://flybase.org/reports/FBgn0261555 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42673, CG3179, CG17357, CG14178, BcDNA:RE71585, BcDNA:RE71517, CG32048, CG34272, Dm_3L:44995" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR006020:PTB/PI domain, IPR011993:PH domain-like" CG42673 11-Aug-17 DroID_v2017_08 "Drer\nos1apa, Drer\si:dkey-34e4.1, Drer\nos1apb" - Cele\dyc-1 Xtro\nos1ap "Mmus\Nos1ap, Mmus\Gm7694" "Hsap\C1orf226, Hsap\NOS1AP" DRSC10264 IK 0.310665047 1.820913291 0.829345832 0.319038732 1.820223427 -0.188356491 FBgn0032698 CG10336 - http://flybase.org/reports/FBgn0032698 protein_coding_gene DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000325249 DNA replication checkpoint ; GO:0000076 | inferred from biological aspect of ancestor with PANTHER:PTN000325249 cell cycle phase transition ; GO:0044770 | inferred from sequence or structural similarity with UniProtKB:Q9BVW5 DNA replication checkpoint ; GO:0000076 | inferred from sequence or structural similarity with UniProtKB:Q9BVW5 positive regulation of cell proliferation ; GO:0008284 | inferred from sequence or structural similarity with UniProtKB:Q9BVW5 intra-S DNA damage checkpoint ; GO:0031573 | inferred from sequence or structural similarity with UniProtKB:Q9BVW5 replication fork arrest ; GO:0043111 | inferred from biological aspect of ancestor with PANTHER:PTN000325249 replication fork protection ; GO:0048478 | inferred from biological aspect of ancestor with PANTHER:PTN000325249 regulation of nuclear cell cycle DNA replication ; GO:0033262 | inferred from biological aspect of ancestor with PANTHER:PTN000325249 replication fork protection complex ; GO:0031298 | inferred from biological aspect of ancestor with PANTHER:PTN000325249 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:Q9BVW5 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9BVW5 CG10336 IPR012923:Chromosome segregation in meiosis protein 3 CG10336 11-Aug-17 DroID_v2017_08 Drer\tipin Scer\CSM3 Cele\F23C8.9 Xtro\tipin Mmus\Tipin Hsap\TIPIN "viable,fertile" FBgn0067777 era errance http://flybase.org/reports/FBgn0067777 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available era - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg,germline clone,oocyte nucleus,egg chamber" FBgn0263377 CR43429 - http://flybase.org/reports/FBgn0263377 non_protein_coding_gene - - - CR43429 - CR43429 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028909 tRNA:Gln-CTG-4-1 transfer RNA:Glutamine-CTG 4-1 http://flybase.org/reports/FBgn0028909 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "BG:DS01514.1, tRNA:gln, AE002690.trna19-GlnCTG, tRNA:Q:CTG:AE002690, CR31838, chr2L.trna28-GlnCTG, tRNA:Gln-CTG-4-1, tRNA:Q:34E, tRNA-Gln-CTG-4-1, CAG" - CR31838 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065679 l(2)SH0670 lethal (2) SH0670 http://flybase.org/reports/FBgn0065679 gene - - - "l(2)SH0670, l(2)SH2 0670" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259188 Ir7f Ionotropic receptor 7f http://flybase.org/reports/FBgn0259188 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir7f, CG15327, DmelIR7f, CG42292, IR7f" - CG42292 11-Aug-17 DroID_v2017_08 "Drer\LOC100537813, Drer\grid1a, Drer\grid1b" - Cele\glr-8 - "Mmus\Grik4, Mmus\Grid1" "Hsap\GRIK3, Hsap\GRID1, Hsap\GRIN2C, Hsap\GRID2" viable FBgn0052798 CG32798 - http://flybase.org/reports/FBgn0052798 protein_coding_gene - - - CG32798 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035380 CG9970 - http://flybase.org/reports/FBgn0035380 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9970 "IPR011705:BTB/Kelch-associated, IPR031750:Domain of unknown function DUF4734" CG9970 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032919 CG9253 - http://flybase.org/reports/FBgn0032919 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000001107 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000618871 - "DmRH24, cg9253, anon-EST:GressD10, CG9253" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG9253 11-Aug-17 DroID_v2017_08 "Drer\tdrd12, Drer\ddx49, Drer\ddx28, Drer\ddx47" "Scer\DRS1, Scer\RRP3, Scer\PRP5" "Cele\T26G10.1, Cele\Y54G11A.3, Cele\rde-12, Cele\H20J04.4, Cele\C24H12.4" "Xtro\ddx28, Xtro\ddx47, Xtro\ddx49" "Mmus\Ddx28, Mmus\Ddx47, Mmus\Ddx49" "Hsap\DDX49, Hsap\DDX47, Hsap\APOLD1, Hsap\DDX28" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260500 Pkn::Rok - http://flybase.org/reports/FBgn0260500 engineered_fusion_gene - - - "Rok-Pkn, Pkn::rok, Pkn::Rok" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030063 CG1789 - http://flybase.org/reports/FBgn0030063 protein_coding_gene molecular_function ; GO:0003674 | no biological data available rRNA processing ; GO:0006364 | inferred from sequence or structural similarity with UniProtKB:P34247 neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal small subunit biogenesis ; GO:0042274 | inferred from biological aspect of ancestor with PANTHER:PTN000303342 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P34247 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000303342 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000303342 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000303342 CG1789 "IPR007144:Small-subunit processome, Utp11" CG1789 11-Aug-17 DroID_v2017_08 Drer\utp11l Scer\UTP11 Cele\C16C10.2 Xtro\utp11l Mmus\Utp11l Hsap\UTP11 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0266141 CR44847 - http://flybase.org/reports/FBgn0266141 non_protein_coding_gene - - - CR44847 - CR44847 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027240 l(1)G0272 lethal (1) G0272 http://flybase.org/reports/FBgn0027240 - gene - - - l(1)G0272 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267861 Maf1 Maf1 http://flybase.org/reports/FBgn0267861 protein_coding_gene RNA polymerase III core binding ; GO:0000994 | inferred from biological aspect of ancestor with PANTHER:PTN000500453 negative regulation of transcription from RNA polymerase III promoter ; GO:0016480 | inferred from mutant phenotype transcription factor TFIIIB complex assembly ; GO:0070217 | inferred from biological aspect of ancestor with PANTHER:PTN000500453 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000500453 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000500453 "Maf1, CG40196, dMaf1, CR41604" IPR015257:Repressor of RNA polymerase III transcription Maf1 CG40196 11-Aug-17 DroID_v2017_08 "Drer\maf1, Drer\zgc:112356" Scer\MAF1 Cele\mafr-1 - Mmus\Maf1 Hsap\MAF1 "developmental rate defective,large body" FBgn0259680 Pkcdelta Protein kinase C delta http://flybase.org/reports/FBgn0259680 protein_coding_gene "protein kinase C activity ; GO:0004697 | inferred from electronic annotation with InterPro:IPR014376 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017892 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 protein phosphorylation ; GO:0006468 | non-traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with inaC intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 "CG42349, PKCdelta, PKCd, Pkcdelta, CG10524, CG11245" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal, IPR014376:Protein kinase C, delta/epsilon/eta/theta types, IPR020454:Diacylglycerol/phorbol-ester binding, IPR015943:WD40/YVTN repeat-like-containing domain" CG42349 11-Aug-17 DroID_v2017_08 "Drer\pimr112, Drer\sgk494a, Drer\prkca, Drer\prkcq, Drer\prkcea, Drer\pkn2, Drer\prkcda, Drer\pkn3, Drer\prkceb, Drer\si:ch211-14c7.2, Drer\prkcha, Drer\prkcg, Drer\prkcbb, Drer\zgc:153916, Drer\pkn1b, Drer\si:ch73-374l24.1, Drer\sgk494b, Drer\prkchb, Drer\pkn1a" "Scer\SPA2, Scer\PKC1, Scer\DUN1" "Cele\tpa-1, Cele\pkc-1, Cele\pkn-1, Cele\pkc-2" "Xtro\prkcg, Xtro\prkcq, Xtro\prkce, Xtro\gpha2, Xtro\prkca, Xtro\prkcd, Xtro\prkch, Xtro\LOC100493742, Xtro\pkn3, Xtro\pkn1, Xtro\tnfrsf1a, Xtro\prkcb" "Mmus\Gm5113, Mmus\Prx, Mmus\Pkn2, Mmus\Pkn3, Mmus\BC030499, Mmus\Prkcd, Mmus\Prkce, Mmus\Pkn1, Mmus\D130040H23Rik, Mmus\Prkca, Mmus\Prkcq, Mmus\Sprr1b, Mmus\Sprr1a, Mmus\Prkch, Mmus\Prkcb, Mmus\Prkcg" "Hsap\PRKCG, Hsap\PKN2, Hsap\PKN1, Hsap\PRKCA, Hsap\PKN3, Hsap\PRKCE, Hsap\PRX, Hsap\PRKCH, Hsap\PRKCB, Hsap\PRKCQ, Hsap\PRKCD, Hsap\SGK494" FBgn0085761 CR40642 - http://flybase.org/reports/FBgn0085761 rRNA_gene - - - CR40642 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263697 Uba3 Ubiquitin activating enzyme 3 http://flybase.org/reports/FBgn0263697 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR014929 acid-amino acid ligase activity ; GO:0016881 | inferred from electronic annotation with InterPro:IPR014929, InterPro:IPR023318 NEDD8 activating enzyme activity ; GO:0019781 | contributes_to inferred from direct assay" negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype protein neddylation ; GO:0045116 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with APP-BP1 "Uba3, CG13343, dUba3, l(2)SH2028, l(2)SH2 2028" "IPR000594:THIF-type NAD/FAD binding fold, IPR014929:E2 binding, IPR030468:NEDD8-activating enzyme E1 catalytic subunit, IPR033127:Ubiquitin-activating enzyme E1, Cys active site" CG13343 11-Aug-17 DroID_v2017_08 Drer\uba3 Scer\UBA3 Cele\rfl-1 Xtro\uba3 Mmus\Uba3 Hsap\UBA3 "visible,partially lethal - majority die,some die during pupal stage,lethal,heat sensitive,recessive" "mesothoracic tergum,wing blade,heat sensitive" FBgn0036598 CG4982 - http://flybase.org/reports/FBgn0036598 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG4982 IPR007614:Retinin-like protein CG4982 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0032247 CG5188 - http://flybase.org/reports/FBgn0032247 protein_coding_gene aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR002467 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR002467 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR002467 - "MAP1B, CG5188" "IPR000994:Peptidase M24, IPR001714:Peptidase M24, methionine aminopeptidase, IPR002467:Peptidase M24A, methionine aminopeptidase, subfamily 1" CG5188 11-Aug-17 DroID_v2017_08 "Drer\metap1d, Drer\metap1" Scer\MAP1 Cele\map-1 "Xtro\metap1, Xtro\metap1d" "Mmus\Metap1d, Mmus\Metap1" "Hsap\METAP1, Hsap\METAP1D" viable FBgn0263485 scaRNA:PsiU2-55 small Cajal body-specific RNA : PsiU2-55 http://flybase.org/reports/FBgn0263485 snoRNA_gene snRNA pseudouridylation guide activity ; GO:0030565 | inferred from direct assay rRNA pseudouridylation guide activity ; GO:0030559 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "snoRNA:prp8-a, CR43600, scaRNA:Prp8, snoRNA:Prp8, scaRNA:PsiU2-55, pugU2-55, snoRNA:Prp8-a, chr2R:7677028..7677241" - CR43600 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030846 CG12992 - http://flybase.org/reports/FBgn0030846 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12992 - CG12992 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029969 CG10932 - http://flybase.org/reports/FBgn0029969 protein_coding_gene acetyl-CoA C-acetyltransferase activity ; GO:0003985 | inferred from biological aspect of ancestor with PANTHER:PTN000432235 acetyl-CoA C-acetyltransferase activity ; GO:0003985 | inferred from sequence or structural similarity with UniProtKB:P24752 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:P24752 sleep ; GO:0030431 | inferred from expression pattern fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000432120 fatty acid biosynthetic process ; GO:0006633 | inferred from sequence or structural similarity with UniProtKB:P24752 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence model microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence model mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P24752 mitochondrion ; GO:0005739 | inferred from direct assay "154229_at, CG10932" "IPR002155:Thiolase, IPR016039:Thiolase-like, IPR020613:Thiolase, conserved site, IPR020615:Thiolase, acyl-enzyme intermediate active site, IPR020616:Thiolase, N-terminal, IPR020617:Thiolase, C-terminal" CG10932 11-Aug-17 DroID_v2017_08 "Drer\acaa2, Drer\acat2, Drer\LOC103910030, Drer\acaa1, Drer\acat1" Scer\ERG10 "Cele\T02G5.7, Cele\kat-1, Cele\acaa-2" "Xtro\acaa1, Xtro\acaa2, Xtro\acat2, Xtro\acat1" "Mmus\Acaa1a, Mmus\Acat1, Mmus\Acat3, Mmus\Acaa1b, Mmus\Acaa2, Mmus\Acat2" "Hsap\ACAA1, Hsap\ACAT1, Hsap\ACAA2, Hsap\ACAT2" "viable,fertile" FBgn0029944 Dok Downstream of kinase http://flybase.org/reports/FBgn0029944 protein_coding_gene insulin receptor binding ; GO:0005158 | inferred from electronic annotation with InterPro:IPR002404 "stress-activated protein kinase signaling cascade ; GO:0031098 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype dorsal closure, elongation of leading edge cells ; GO:0007394 | inferred from mutant phenotype" cell cortex ; GO:0005938 | inferred from direct assay "CG2079, Ddok, l(1)G0331, Dok" "IPR001849:Pleckstrin homology domain, IPR002404:IRS-type PTB domain, IPR011993:PH domain-like" CG2079 11-Aug-17 DroID_v2017_08 "Drer\frs2a, Drer\dok4, Drer\frs2b, Drer\dok6, Drer\dok2, Drer\frs3, Drer\dok3, Drer\dok1a, Drer\dok1b" - Cele\rog-1 "Xtro\frs2, Xtro\dok4, Xtro\frs3, Xtro\dok2, Xtro\dok5, Xtro\dok1" "Mmus\Dok3, Mmus\Dok7, Mmus\Dok6, Mmus\Dok4, Mmus\Frs3, Mmus\Frs2, Mmus\Dok5, Mmus\Dok1, Mmus\Dok2" "Hsap\DOK1, Hsap\FRS3, Hsap\DOK5, Hsap\DOK4, Hsap\DOK3, Hsap\DOK7, Hsap\DOK6, Hsap\DOK2, Hsap\FRS2" "lethal,partially lethal - majority die,male,germline clone,rescuable maternal effect,cell shape defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "wing,heart primordium,thorax,chaeta,orbital bristle,interommatidial bristle,embryonic/first instar larval cuticle,dorsal,germline clone,rescuable maternal effect,embryonic leading edge cell & filamentous actin | germ-line clone" DRSC18204 I -0.704290753 -2.361072177 -0.076479879 -0.152288394 1.20745313 0.049122377 FBgn0023071 l(1)1Eg lethal (1) 1Eg http://flybase.org/reports/FBgn0023071 - gene - - - "DCE-21, DCE-17, l(1)1Eg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025815 Mcm6 Minichromosome maintenance 6 http://flybase.org/reports/FBgn0025815 FBgn0000821 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008049, InterPro:IPR018525 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008049, InterPro:IPR018525 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR008049 DNA replication ; GO:0006260 | traceable author statement eggshell chorion gene amplification ; GO:0007307 | traceable author statement oogenesis ; GO:0048477 | traceable author statement eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype MCM complex ; GO:0042555 | inferred from electronic annotation with InterPro:IPR008049 nucleus ; GO:0005634 | inferred from direct assay "mcm6, MCM6, DmMCM6, fs(1)K1214, CG4039, Mcm6, McM6, DmeMCM6, dMcm6" "IPR018525:Mini-chromosome maintenance, conserved site, IPR001208:MCM domain, IPR008049:DNA replication licensing factor Mcm6, IPR012340:Nucleic acid-binding, OB-fold, IPR033762:MCM OB domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027925:MCM N-terminal domain, IPR031327:Mini-chromosome maintenance protein" CG4039 11-Aug-17 DroID_v2017_08 "Drer\mcm8, Drer\mcm6l, Drer\mcm6, Drer\mcmdc2" Scer\MCM6 Cele\mcm-6 "Xtro\mcm6.2, Xtro\mcm8, Xtro\mcm6" "Mmus\Mcm6, Mmus\Mcmdc2, Mmus\Mcm8" "Hsap\MCM6, Hsap\MCM8, Hsap\MCMDC2" " egg stage | unfertilized egg , adult stage | female , embryonic stage | stage 11-12 , embryonic stage | 0-4 hr " " unfertilized egg

, embryonic central nervous system

" "viable,female sterile,lethal,recessive,small body,female sterile soma-dependent,reduced,wild-type,visible" "chorion,embryonic/larval brain,imaginal disc,egg,maternal effect,chorion | maternal effect,dorsal appendage,chaeta" FBgn0085570 CR41243 - http://flybase.org/reports/FBgn0085570 pseudogene_attribute - - - "CG41243, CR41243" - CR41243 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044114 E(rst)C162 E(rst)C162 http://flybase.org/reports/FBgn0044114 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C162, E(rst)C162" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039537 CG5590 - http://flybase.org/reports/FBgn0039537 protein_coding_gene - - peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:18572 inferred from sequence model lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay CG5590 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR003033:SCP2 sterol-binding domain, IPR016040:NAD(P)-binding domain" CG5590 11-Aug-17 DroID_v2017_08 "Drer\hsd17b14, Drer\scp2a, Drer\zgc:113054, Drer\decr1, Drer\stoml1, Drer\dhrs1, Drer\hsdl2, Drer\bdh2, Drer\decr2, Drer\pecr" "Scer\OAR1, Scer\SPS19" "Cele\dhs-18, Cele\dhs-6" "Xtro\MGC147226, Xtro\decr1, Xtro\stoml1, Xtro\pecr, Xtro\dhrs4, Xtro\hsd17b14, Xtro\hsdl2, Xtro\decr2, Xtro\scp2" "Mmus\Decr2, Mmus\Hsd17b14, Mmus\Scp2, Mmus\Decr1, Mmus\Bdh2, Mmus\Dhrs4, Mmus\Stoml1, Mmus\Scp2d1, Mmus\Dhrs1, Mmus\Pecr, Mmus\Dhrs2, Mmus\Hsdl2" "Hsap\SCP2, Hsap\DHRS4, Hsap\DECR1, Hsap\HSDL2, Hsap\STOML1, Hsap\HSD17B14, Hsap\DHRS4L2, Hsap\BDH2, Hsap\DHRS1, Hsap\DECR2, Hsap\SCP2D1, Hsap\DHRS2, Hsap\PECR" "viable,visible" trichogen cell FBgn0031181 Ir20a Ionotropic receptor 20a http://flybase.org/reports/FBgn0031181 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir20a, DmelIR20a, CG14584, IR20a" - CG14584 11-Aug-17 DroID_v2017_08 "Drer\LOC100537813, Drer\grid1a, Drer\grid1b, Drer\grid2, Drer\grik5, Drer\grik2, Drer\LOC100334689" - "Cele\F59E12.8, Cele\glr-6, Cele\glr-3" - "Mmus\Grik5, Mmus\Grid1, Mmus\Grid2, Mmus\Grik2, Mmus\Grik3" "Hsap\GRIK5, Hsap\GRIK2, Hsap\GRID2, Hsap\GRIK3, Hsap\GRID1" viable FBgn0261724 EC201 - http://flybase.org/reports/FBgn0261724 gene - - - EC201 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0260034 siren8 siren 8 http://flybase.org/reports/FBgn0260034 gene - - - siren8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0029092 ced-6 ced-6 http://flybase.org/reports/FBgn0029092 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W0A0 mushroom body development ; GO:0016319 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype - "ced-6, CG11804, drced-6, dCed-6, dced-6, ced6, drCed-6, Ced-6" "IPR006020:PTB/PI domain, IPR011993:PH domain-like" CG11804 11-Aug-17 DroID_v2017_08 "Drer\ldlrap1b, Drer\si:dkey-71h2.2, Drer\appl2, Drer\gulp1a, Drer\gulp1b, Drer\appl1, Drer\ldlrap1a" - Cele\ced-6 "Xtro\appl2, Xtro\ldlrap1, Xtro\appl1, Xtro\gulp1" "Mmus\Appl1, Mmus\Anks1b, Mmus\Appl2, Mmus\Ldlrap1, Mmus\Gulp1" "Hsap\GULP1, Hsap\APPL1, Hsap\APPL2, Hsap\LDLRAP1" "viable,fertile,neuroanatomy defective" "embryonic hemocyte,ensheathing neuropil associated glial cell,glial cell" FBgn0084667 l(3)S066607 l(3)S066607 http://flybase.org/reports/FBgn0084667 gene - - - l(3)S066607 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052009 CR32009 - http://flybase.org/reports/FBgn0052009 pseudogene_attribute - - - "CG32009, CR32009" - CR32009 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069995 BG01799 BG01799 http://flybase.org/reports/FBgn0069995 gene - - - BG01799 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0083243 EP1207 EP1207 http://flybase.org/reports/FBgn0083243 gene - - - EP1207 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005318 nicked-eye nicked eye http://flybase.org/reports/FBgn0005318 - gene - - - "nicked-eye, ne" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0002371 l(3)91Fc lethal (3) 91Fc http://flybase.org/reports/FBgn0002371 - gene - - - "l(DIX43)c5, l(3)C5, l(3)BE62, l(3)BE61, l(3)BE60, C5, l(3)91Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266954 CR45405 - http://flybase.org/reports/FBgn0266954 non_protein_coding_gene - - - CR45405 - CR45405 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032160 CG4598 - http://flybase.org/reports/FBgn0032160 protein_coding_gene enoyl-CoA hydratase activity ; GO:0004300 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 mitochondrion ; GO:0005739 | inferred from direct assay CG4598 "IPR029045:ClpP/crotonase-like domain, IPR001753:Crotonase superfamily" CG4598 11-Aug-17 DroID_v2017_08 Drer\eci1 - - Xtro\eci1 Mmus\Eci1 Hsap\ECI1 "viable,fertile" FBgn0060313 l(3)S147804 lethal (3) S147804 http://flybase.org/reports/FBgn0060313 gene - - - "1478/04, l(3)S147804" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0051089 CG31089 - http://flybase.org/reports/FBgn0051089 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - "CG5990, CG31089" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG31089 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH1, Scer\TGL1, Scer\YEH2" "Cele\lipl-5, Cele\lipl-1, Cele\lipl-6, Cele\lipl-7, Cele\lipl-2, Cele\lipl-3, Cele\lipl-8, Cele\lipl-4" Xtro\lipa "Mmus\Lipk, Mmus\Lipa, Mmus\Lipo2, Mmus\Lipo3, Mmus\Lipm, Mmus\Lipf, Mmus\Lipo4, Mmus\Lipo1, Mmus\Lipn" "Hsap\LIPK, Hsap\LIPJ, Hsap\LIPM, Hsap\LIPA, Hsap\LIPN, Hsap\LIPF" viable FBgn0022130 l(2)k06408 lethal (2) k06408 http://flybase.org/reports/FBgn0022130 - gene - - - l(2)k06408 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032615 CG6012 - http://flybase.org/reports/FBgn0032615 protein_coding_gene - - - CG6012 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG6012 11-Aug-17 DroID_v2017_08 "Drer\hsdl1, Drer\hsd17b12a, Drer\hsd17b12b, Drer\hsd17b3, Drer\hsd20b2" Scer\IFA38 "Cele\dhs-27, Cele\stdh-1, Cele\stdh-4, Cele\dhs-5, Cele\stdh-3, Cele\let-767, Cele\stdh-2" "Xtro\hsd17b12, Xtro\hsdl1, Xtro\LOC100497556" "Mmus\Hsdl1, Mmus\Hsd17b3, Mmus\Hsd17b12" "Hsap\HSD17B3, Hsap\HSD17B12, Hsap\HSDL1" FBgn0020798 nls nineless http://flybase.org/reports/FBgn0020798 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available nls - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0040123 l(2)23CDe lethal (2) 23CDe http://flybase.org/reports/FBgn0040123 gene - - - l(2)23CDe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033885 DJ-1alpha DJ-1alpha http://flybase.org/reports/FBgn0033885 protein_coding_gene - phosphatidylinositol 3-kinase signaling ; GO:0014065 | inferred from genetic interaction with Pi3K92E response to oxidative stress ; GO:0006979 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from direct assay regulation of protein kinase B signaling ; GO:0051896 | inferred from mutant phenotype inferred from genetic interaction with Akt1 mitochondrial ATP synthesis coupled electron transport ; GO:0042775 | inferred from genetic interaction with dj-1β dopamine metabolic process ; GO:0042417 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype - "DJ-1A, CG6646, DJ-1alpha, DJ-1, DJ-1a, Dj-1alpha" "IPR002818:DJ-1/PfpI, IPR006287:Protein DJ-1, IPR029062:Class I glutamine amidotransferase-like" CG6646 11-Aug-17 DroID_v2017_08 Drer\park7 - "Cele\djr-1.2, Cele\djr-1.1" Xtro\park7 Mmus\Park7 Hsap\PARK7 "stress response defective,short lived,locomotor behavior defective,viable,fertile,lethal,recessive,increased cell death,visible,chemical sensitive,lethal - all die before end of larval stage,some die during larval stage,chemical resistant" "eye,eye photoreceptor cell,ommatidium,dopaminergic neuron" FBgn0266223 CR44918 - http://flybase.org/reports/FBgn0266223 non_protein_coding_gene - - - CR44918 - CR44918 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060653 l(3)S083207 lethal (3) S083207 http://flybase.org/reports/FBgn0060653 gene - - - "0832/07, l(3)S083207" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265861 CR44650 - http://flybase.org/reports/FBgn0265861 non_protein_coding_gene - - - "lincRNA.364, CR44650" - CR44650 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032741 Sidpn similar to Deadpan http://flybase.org/reports/FBgn0032741 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003650 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with H" - "CG10446, side, Sidestep, bHLHe51, Side, Sidpn" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG10446 11-Aug-17 DroID_v2017_08 "Drer\her11, Drer\her15.1, Drer\her5, Drer\hey1, Drer\hey2, Drer\LOC100149863, Drer\her6, Drer\her12, Drer\helt, Drer\her4.4, Drer\her3, Drer\her4.3, Drer\her9, Drer\bhlhe40, Drer\her8a, Drer\heyl, Drer\her7, Drer\hes2.2, Drer\hes2.1, Drer\hes6, Drer\her4.2, Drer\her8.2, Drer\her15.2, Drer\her13, Drer\her2, Drer\her1, Drer\bhlhe41" Scer\PHO4 "Cele\lin-22, Cele\hlh-27, Cele\hlh-25" "Xtro\hey1, Xtro\bhlhe40, Xtro\hes7.1, Xtro\hes1, Xtro\hes2, Xtro\hes7.2, Xtro\bhlhe41, Xtro\hes6.1, Xtro\hes4, Xtro\hey2" "Mmus\Hes2, Mmus\Hes5, Mmus\Hes3, Mmus\Bhlhe41, Mmus\Hey1, Mmus\Helt, Mmus\Heyl, Mmus\Hes1, Mmus\Hes7, Mmus\Bhlhe40, Mmus\Hey2, Mmus\Hes6" "Hsap\HES3, Hsap\HELT, Hsap\HES4, Hsap\HES5, Hsap\HEY1, Hsap\HES6, Hsap\HES1, Hsap\HES7, Hsap\BHLHE41, Hsap\BHLHE40, Hsap\HES2, Hsap\HEY2, Hsap\HEYL" viable FBgn0015847 akaal akaal http://flybase.org/reports/FBgn0015847 - gene - - - akaal - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,behavior defective" FBgn0085478 CG34449 - http://flybase.org/reports/FBgn0085478 protein_coding_gene palmitoyltransferase activity ; GO:0016409 | inferred from biological aspect of ancestor with PANTHER:PTN000525808 protein palmitoylation ; GO:0018345 | inferred from biological aspect of ancestor with PANTHER:PTN000525808 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000525808 "CG34449, CG17251, p16, CG32705, CG15372, CG12136, pen16, anon-Pen16, Pen16, Dm_X:47283" "IPR001594:Palmitoyltransferase, DHHC domain, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG34449 11-Aug-17 DroID_v2017_08 "Drer\LOC569920, Drer\zdhhc5a, Drer\zdhhc22, Drer\zgc:77880, Drer\zdhhc8b, Drer\zdhhc5b, Drer\zdhhc23b, Drer\zdhhc4, Drer\zdhhc24, Drer\zdhhc21, Drer\zdhhc1, Drer\zdhhc9, Drer\zdhhc12a, Drer\zdhhc7, Drer\zdhhc12b, Drer\zdhhc23a, Drer\zdhhc3a, Drer\zdhhc14, Drer\zdhhc18a, Drer\zdhhc8a, Drer\LOC100334198, Drer\zdhhc3b" "Scer\SWF1, Scer\ERF2, Scer\PFA5" "Cele\dhhc-8, Cele\dhhc-2" "Xtro\zdhhc24, Xtro\zdhhc12, Xtro\zdhhc9, Xtro\zdhhc1, Xtro\dnz1, Xtro\zdhhc8, Xtro\zdhhc21, Xtro\zdhhc3, Xtro\zdhhc7, Xtro\zdhhc14" "Mmus\Zdhhc21, Mmus\Zdhhc8, Mmus\Zdhhc3, Mmus\Zdhhc4, Mmus\Zdhhc23, Mmus\Zdhhc9, Mmus\Zdhhc5, Mmus\Zdhhc1, Mmus\Zdhhc24, Mmus\Zdhhc14, Mmus\Zdhhc19, Mmus\Zdhhc18, Mmus\Zdhhc11, Mmus\Zdhhc7, Mmus\Zdhhc12, Mmus\Zdhhc25, Mmus\Zdhhc22" "Hsap\ZDHHC19, Hsap\ZDHHC14, Hsap\ZDHHC23, Hsap\ZDHHC3, Hsap\ZDHHC4, Hsap\ZDHHC18, Hsap\ZDHHC21, Hsap\ZDHHC24, Hsap\ZDHHC8, Hsap\ZDHHC12, Hsap\ZDHHC11, Hsap\ZDHHC22, Hsap\ZDHHC7, Hsap\ZDHHC1, Hsap\ZDHHC5, Hsap\ZDHHC9" "viable,fertile" DRSC18044 IE -1.493607302 -4.337825011 -1.792982816 -3.015518462 -0.260090102 -0.679934595 FBgn0052207 CR32207 - http://flybase.org/reports/FBgn0052207 pseudogene_attribute - - - "BcDNA:LD41276, CG32207, CR32207, hp-CR32207" - CR32207 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040994 CR17567 - http://flybase.org/reports/FBgn0040994 non_protein_coding_gene - - - "bs36b02.y1, bs35c03.y1, BcDNA:GH05530, anon-WO0140519.80, CR17567, CG17567" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004787 anon-h anon AT-rich sequence http://flybase.org/reports/FBgn0004787 - repeat_region - - - anon-h - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050011 gem gemini http://flybase.org/reports/FBgn0050011 protein_coding_gene - - - "CG30011, CG11867, CG3459, dCP2, anon-AE003830.1, BcDNA:HL07889, gem" "IPR007604:CP2 transcription factor, IPR013761:Sterile alpha motif/pointed domain, IPR001660:Sterile alpha motif domain" CG30011 11-Aug-17 DroID_v2017_08 "Drer\grhl2b, Drer\tfcp2l1, Drer\grhl2a, Drer\grhl1, Drer\grhl3, Drer\tfcp2, Drer\ubp1" - Cele\grh-1 "Xtro\grhl3, Xtro\ubp1, Xtro\grhl2, Xtro\tfcp2, Xtro\grhl1" "Mmus\Ubp1, Mmus\Grhl2, Mmus\Grhl3, Mmus\Grhl1, Mmus\Tfcp2, Mmus\Tfcp2l1" "Hsap\GRHL1, Hsap\UBP1, Hsap\TFCP2L1, Hsap\GRHL2, Hsap\TFCP2, Hsap\GRHL3" "viable,fertile" FBgn0043574 S(faf)196 S(faf)196 http://flybase.org/reports/FBgn0043574 gene - - - S(faf)196 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028140 l(3)S047916 lethal (3) S047916 http://flybase.org/reports/FBgn0028140 gene - - - "0479/16, l(3)S047916" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267816 CR46141 - http://flybase.org/reports/FBgn0267816 non_protein_coding_gene - - - CR46141 - CR46141 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003100 PL(2)sp-G1 Polygenic locuis sternopleural G1 http://flybase.org/reports/FBgn0003100 - gene - - - "PL(2)sp[G1], PL(2)sp-G1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031011 CG8034 - http://flybase.org/reports/FBgn0031011 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG8034 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8034 11-Aug-17 DroID_v2017_08 "Drer\slc16a5b, Drer\slc16a6a, Drer\slc16a12a, Drer\slc16a6b, Drer\slc16a12b, Drer\slc16a13" "Scer\MCH2, Scer\MCH5, Scer\MCH4, Scer\ATG22, Scer\ESBP6" Cele\slcf-1 Xtro\slc16a6 "Mmus\Slc16a1, Mmus\Slc16a12, Mmus\Slc16a4, Mmus\Slc16a6" "Hsap\SLC16A3, Hsap\SLC16A13, Hsap\SLC16A4, Hsap\SLC16A7, Hsap\SLC16A1, Hsap\SLC16A12, Hsap\SLC16A6" DRSC20076 E -0.460834588 -0.852346825 1.197513651 -2.125196752 -0.009531845 0.057048702 FBgn0002482 l(3)SG41 lethal (3) SG41 http://flybase.org/reports/FBgn0002482 FBgn0004723 gene - - - "l(3)ds9, l(3)B9, l(3)SG41" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "imaginal disc,mitosis & nuclear chromosome" FBgn0060928 l(3)S042018 lethal (3) S042018 http://flybase.org/reports/FBgn0060928 gene - - - "0420/18, l(3)S042018" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032010 CG8086 - http://flybase.org/reports/FBgn0032010 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - "CG8113, CG8086" IPR010736:Sperm-tail PG-rich repeat CG8086 11-Aug-17 DroID_v2017_08 "Drer\zgc:110183, Drer\nup62l, Drer\stpg1, Drer\odf3l2, Drer\stpg2, Drer\odf3b, Drer\nup98, Drer\nup58" "Scer\NUP116, Scer\NUP1, Scer\NSP1, Scer\NUP159, Scer\NUP100, Scer\NUP49, Scer\NUP145" "Cele\npp-11, Cele\npp-10" "Xtro\nup153, Xtro\odf3l1, Xtro\odf3" "Mmus\Stpg2, Mmus\Odf3, Mmus\Odf3l1, Mmus\Odf3l2, Mmus\Nupl1, Mmus\Nup98, Mmus\Nup62cl, Mmus\Odf3b, Mmus\Nup62, Mmus\Stpg3" "Hsap\STPG3, Hsap\STPG2, Hsap\NUP62, Hsap\NUP98, Hsap\NUP58, Hsap\ODF3B, Hsap\ODF3, Hsap\NUP153, Hsap\ODF3L1, Hsap\ODF3L2" "viable,fertile,auditory perception defective,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0267217 CR45657 - http://flybase.org/reports/FBgn0267217 non_protein_coding_gene - - - CR45657 - CR45657 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039177 CG13611 - http://flybase.org/reports/FBgn0039177 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" - CG13611 "IPR002937:Amine oxidase, IPR023753:FAD/NAD(P)-binding domain" CG13611 11-Aug-17 DroID_v2017_08 "Drer\mao, Drer\si:ch211-127i16.2" - Cele\amx-2 - - Hsap\MAOA "viable,visible" trichogen cell DRSC14614 E 0.341219879 0.06941403 1.7901796 -0.577721268 -0.439798134 -0.31191783 FBgn0002268 l(3)69Ag lethal (3) 69Ag http://flybase.org/reports/FBgn0002268 - gene - - - "rsg30, l(3)rsg30, l(3)69Ag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267714 CR46047 - http://flybase.org/reports/FBgn0267714 non_protein_coding_gene - - - CR46047 - CR46047 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037978 KLHL18 Kelch like family member 18 http://flybase.org/reports/FBgn0037978 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 protein homodimerization activity ; GO:0042803 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity "imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype" Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from genetic interaction with Cul3 inferred from physical interaction with Cul3 "anon-WO0118547.179, CG3571, KLHL18, dKLHL18" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011705:BTB/Kelch-associated, IPR011043:Galactose oxidase/kelch, beta-propeller, IPR011333:SKP1/BTB/POZ domain, IPR017096:BTB-kelch protein, IPR015915:Kelch-type beta propeller" CG3571 11-Aug-17 DroID_v2017_08 "Drer\klhl2, Drer\klhl18, Drer\klhl5, Drer\klhl20, Drer\klhl12, Drer\klhl17, Drer\klhl3" - "Cele\bath-27, Cele\bath-4, Cele\F14D2.15, Cele\math-29, Cele\math-40, Cele\bath-5, Cele\bath-1, Cele\bath-26, Cele\bath-3, Cele\kel-1, Cele\bath-25, Cele\bath-47, Cele\math-13, Cele\bath-29, Cele\math-20, Cele\btb-4, Cele\btb-8, Cele\bath-24, Cele\bath-46, Cele\btb-9, Cele\math-38, Cele\bath-45, Cele\bath-19, Cele\btb-17, Cele\math-50, Cele\bath-10, Cele\math-1, Cele\hpo-9, Cele\bath-33, Cele\bath-15, Cele\bath-20, Cele\sdz-18, Cele\btb-7, Cele\btb-12, Cele\R12E2.1, Cele\sdz-28, Cele\btb-2, Cele\bath-23, Cele\bath-9, Cele\bath-2, Cele\bath-31, Cele\bath-35, Cele\btb-10, Cele\bath-13, Cele\btb-16, Cele\bath-7, Cele\bath-21, Cele\bath-36, Cele\bath-38, Cele\bath-30, Cele\K08E4.7, Cele\kel-3" "Xtro\klhl18, Xtro\klhl12, Xtro\klhl20, Xtro\klhl17, Xtro\klhl4, Xtro\klhl5" "Mmus\Klhl3, Mmus\Klhl2, Mmus\Klhl18, Mmus\Klhl17, Mmus\Klhl5, Mmus\Klhl20, Mmus\Klhl12, Mmus\Klhl1, Mmus\Klhl4" "Hsap\KLHL20, Hsap\KLHL12, Hsap\KLHL17, Hsap\KLHL2, Hsap\KLHL1, Hsap\KLHL3, Hsap\KLHL18, Hsap\KLHL4, Hsap\KLHL5" "viable,visible" "trichogen cell,scutellar bristle,adult external thorax,dorsal" DRSC26629 K -0.883204359 -0.451477481 -0.063146963 -0.716131096 1.633154256 0.321223323 FBgn0259267 C736 - http://flybase.org/reports/FBgn0259267 gene - - - C736 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0086408 stl stall http://flybase.org/reports/FBgn0086408 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001590 metalloendopeptidase activity ; GO:0004222 | inferred from sequence model zinc ion binding ; GO:0008270 | inferred from sequence model proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001590 negative regulation of neuron migration ; GO:2001223 | inferred from mutant phenotype ovarian follicle development ; GO:0001541 | inferred from mutant phenotype ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "stl, CG3622, fs(2)A16, BcDNA:GM08694" "IPR001590:Peptidase M12B, ADAM/reprolysin, IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR024079:Metallopeptidase, catalytic domain" CG3622 11-Aug-17 DroID_v2017_08 "Drer\adamts13, Drer\LOC100002059, Drer\adamts5, Drer\si:ch73-237c6.1, Drer\cfp, Drer\adamts9, Drer\adamts1, Drer\adamts8a, Drer\adamts15a" - "Cele\mig-17, Cele\gon-1, Cele\T19D2.1, Cele\adt-1, Cele\adt-2, Cele\C36B7.5" Xtro\adamts13 "Mmus\Adamts8, Mmus\Adamts15, Mmus\Adamts5, Mmus\Cfp, Mmus\Adamts4, Mmus\Adamts1, Mmus\Adamts20, Mmus\Adamts9, Mmus\Adamts13" "Hsap\ADAMTS1, Hsap\ADAMTS15, Hsap\ADAMTS8, Hsap\ADAMTS9, Hsap\ADAMTS5, Hsap\ADAMTS20, Hsap\CFP, Hsap\ADAMTS4, Hsap\ADAMTS13" FBgn0034205 CG10950 - http://flybase.org/reports/FBgn0034205 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 CG10950 "IPR013598:Exportin-1/Importin-beta-like, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG10950 11-Aug-17 DroID_v2017_08 Drer\tnpo3 "Scer\KAP122, Scer\MTR10" Cele\tsr-1 Xtro\tnpo3 Mmus\Tnpo3 Hsap\TNPO3 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266472 hazelnut - http://flybase.org/reports/FBgn0266472 gene - - - hazelnut - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "germline cyst,germline clone,oocyte,centrosome | germline clone" FBgn0035252 CG7970 - http://flybase.org/reports/FBgn0035252 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 cytosol ; GO:0005829 | inferred from direct assay "anon-WO0118547.268, CG7970" IPR007248:Mpv17/PMP22 CG7970 11-Aug-17 DroID_v2017_08 "Drer\mpv17, Drer\si:ch211-120k19.1, Drer\pxmp2, Drer\mpv17l2" "Scer\YOR292C, Scer\SYM1" "Cele\ZK470.1, Cele\T18D3.9" "Xtro\mpv17l2, Xtro\pxmp2" "Mmus\Mpv17l, Mmus\Mpv17, Mmus\Pxmp2, Mmus\Mpv17l2" "Hsap\PGAM5, Hsap\PXMP2, Hsap\MPV17L, Hsap\MPV17L2, Hsap\MPV17" viable FBgn0033387 CG8008 - http://flybase.org/reports/FBgn0033387 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG8008 "IPR020846:Major facilitator superfamily domain, IPR011701:Major facilitator superfamily" CG8008 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-5g14.1, Drer\zgc:174356, Drer\slc46a1, Drer\hiat1a, Drer\slc46a3, Drer\LOC100002406, Drer\LOC557306, Drer\si:ch211-262i1.4, Drer\hiat1b" Scer\YJL163C "Cele\F40F9.5, Cele\Y43F8A.5, Cele\C46C11.2, Cele\Y4C6B.5" "Xtro\mfsd14a, Xtro\mfsd14b, Xtro\slc46a2, Xtro\slc46a1" "Mmus\Slc46a2, Mmus\Mfsd14b, Mmus\Slc46a1, Mmus\Slc46a3, Mmus\Mfsd14a" "Hsap\SLC46A1, Hsap\SLC46A2, Hsap\MFSD14A, Hsap\MFSD14B, Hsap\SLC46A3" "viable,fertile,visible" trichogen cell FBgn0030887 CG6867 - http://flybase.org/reports/FBgn0030887 protein_coding_gene - motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype - "CT21241, CG6867" "IPR003112:Olfactomedin-like domain, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR008160:Collagen triple helix repeat, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003599:Immunoglobulin subtype" CG6867 11-Aug-17 DroID_v2017_08 "Drer\zgc:153049, Drer\LOC101883924, Drer\col4a5, Drer\col9a1b, Drer\col6a1, Drer\col9a2, Drer\olfml2bb, Drer\col5a2b, Drer\col27a1a, Drer\LOC797571, Drer\col28a1a, Drer\col11a1a, Drer\col12a1b, Drer\olfml2ba, Drer\adgrl1.1, Drer\si:ch211-173a9.6, Drer\si:ch211-196i2.1, Drer\col27a1b, Drer\gldn, Drer\zgc:110372, Drer\col11a2, Drer\negr1, Drer\col6a4a, Drer\lsamp, Drer\col4a6, Drer\si:ch211-194m7.8, Drer\si:dkey-61l1.4, Drer\si:ch211-194m7.4, Drer\si:ch211-173a9.7, Drer\col5a2a, Drer\opcml, Drer\col11a1b, Drer\si:ch211-194m7.5, Drer\LOC100538221, Drer\col14a1a, Drer\adgrl2a, Drer\col1a1b, Drer\col7a1l, Drer\col17a1b, Drer\col4a2, Drer\col9a1a, Drer\olfm2b, Drer\col5a1, Drer\col6a2, Drer\adgrl1a, Drer\col16a1, Drer\col6a3, Drer\olfm1b, Drer\col2a1b, Drer\olfml3b, Drer\col1a2, Drer\LOC101884357, Drer\olfm3a, Drer\ntm, Drer\olfm3b, Drer\olfml1, Drer\myoc, Drer\col1a1a, Drer\si:ch211-106n13.3, Drer\olfml2a, Drer\wu:fc38h03, Drer\olfm1a, Drer\col2a1a, Drer\olfml3a, Drer\si:dkey-225n22.4, Drer\LOC100330530, Drer\olfm2a, Drer\adgrl3.1" - "Cele\rig-5, Cele\unc-122, Cele\cof-2, Cele\F07A5.4" "Xtro\col2a1, Xtro\col7a1, Xtro\col1a2, Xtro\olfml2b, Xtro\col27a1, Xtro\gldn, Xtro\lsamp, Xtro\LOC100486063, Xtro\col24a1, Xtro\col4a6, Xtro\col4a5, Xtro\olfm3, Xtro\col1a1, Xtro\col5a1, Xtro\col4a1, Xtro\negr1, Xtro\ntm, Xtro\col4a2, Xtro\olfml2a, Xtro\olfml3, Xtro\olfm4, Xtro\olfm1, Xtro\col14a1, Xtro\olfm2, Xtro\adgrl1, Xtro\olfml1, Xtro\col3a1, Xtro\col11a2, Xtro\col6a2" "Mmus\Col6a3, Mmus\Col1a2, Mmus\Negr1, Mmus\4933412E24Rik, Mmus\Olfml2b, Mmus\Col6a4, Mmus\Col2a1, Mmus\Col13a1, Mmus\Col4a2, Mmus\Col23a1, Mmus\Col9a1, Mmus\Col5a1, Mmus\Col28a1, Mmus\Olfml1, Mmus\Col25a1, Mmus\Olfm4, Mmus\Col14a1, Mmus\Col4a6, Mmus\Olfm2, Mmus\Iglon5, Mmus\Opcml, Mmus\Col9a3, Mmus\Col4a4, Mmus\Olfml3, Mmus\Tnn, Mmus\Col1a1, Mmus\Col4a1, Mmus\Col6a1, Mmus\Col6a6, Mmus\Col4a5, Mmus\Olfm5, Mmus\Col27a1, Mmus\Col5a2, Mmus\Olfml2a, Mmus\Col19a1, Mmus\Olfm3, Mmus\Col22a1, Mmus\Vwa1, Mmus\Col3a1, Mmus\Col24a1, Mmus\Myoc, Mmus\Col5a3, Mmus\Lsamp, Mmus\Adgrl3, Mmus\Col11a1, Mmus\Gldn, Mmus\Col4a3, Mmus\Col6a5, Mmus\Col17a1, Mmus\Vwa2, Mmus\Col7a1, Mmus\Col20a1, Mmus\Col16a1, Mmus\Ntm, Mmus\Adgrl2, Mmus\Olfm1, Mmus\8030474K03Rik, Mmus\Col11a2, Mmus\Adgrl1" "Hsap\OLFML2A, Hsap\COL16A1, Hsap\ADGRL3, Hsap\OLFML1, Hsap\OLFML2B, Hsap\GLDN, Hsap\OLFM2, Hsap\COL9A3, Hsap\LSAMP, Hsap\COL3A1, Hsap\COL1A2, Hsap\NEGR1, Hsap\COL5A3, Hsap\COL1A1, Hsap\COL4A3, Hsap\MYOC, Hsap\COL5A1, Hsap\COL6A3, Hsap\COL24A1, Hsap\COL4A6, Hsap\OLFM3, Hsap\COL25A1, Hsap\IGLON5, Hsap\COLQ, Hsap\ADGRL2, Hsap\COL23A1, Hsap\VWA2, Hsap\OLFM4, Hsap\COL27A1, Hsap\COL7A1, Hsap\COL2A1, Hsap\COL6A1, Hsap\COL6A6, Hsap\COL19A1, Hsap\ADGRL1, Hsap\COL5A2, Hsap\COL17A1, Hsap\OPCML, Hsap\COL20A1, Hsap\COL9A2, Hsap\COL6A5, Hsap\COL14A1, Hsap\OLFM1, Hsap\COL22A1, Hsap\COL9A1, Hsap\COL4A5, Hsap\COL11A2, Hsap\VWA1, Hsap\COL11A1, Hsap\COL4A1, Hsap\COL4A2, Hsap\NTM, Hsap\OLFML3, Hsap\COL4A4" viable FBgn0023057 l(1)2Ff lethal (1) 2Ff http://flybase.org/reports/FBgn0023057 - gene - - - "1200E17a, l(1)2Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034315 CG5721 - http://flybase.org/reports/FBgn0034315 protein_coding_gene molecular_function ; GO:0003674 | no biological data available hematopoietic progenitor cell differentiation ; GO:0002244 | inferred from biological aspect of ancestor with PANTHER:PTN000527910 - CG5721 "IPR000225:Armadillo, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG5721 11-Aug-17 DroID_v2017_08 Drer\armc6 - - Xtro\armc6 Mmus\Armc6 Hsap\ARMC6 viable FBgn0034592 CG9406 - http://flybase.org/reports/FBgn0034592 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "CG9406, CBP5" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG9406 11-Aug-17 DroID_v2017_08 "Drer\tnnc1a, Drer\pvalb8, Drer\calml4a, Drer\si:ch211-197n1.2, Drer\calm2a, Drer\cabp1a, Drer\pvalb3, Drer\calb1, Drer\pvalb2, Drer\calm1b, Drer\calml4b, Drer\caln2, Drer\tnnc1b, Drer\cabp5b, Drer\calm1a, Drer\calm3a, Drer\calb2b, Drer\pvalb6, Drer\pvalb9, Drer\cabp5a, Drer\tnnc2, Drer\calb2a, Drer\efcab11, Drer\calm3b, Drer\caln1, Drer\pvalb4, Drer\scgn, Drer\efcab2, Drer\cabp2a, Drer\efcab6, Drer\cabp7b, Drer\pvalb1, Drer\rhbdl3, Drer\calm2b" "Scer\CMD1, Scer\CDC31, Scer\MLC1, Scer\MLC2" "Cele\cal-7, Cele\T02G5.3, Cele\cal-2" "Xtro\calm1, Xtro\LOC548651, Xtro\tnnc1, Xtro\calb1, Xtro\calm2, Xtro\pvalb.1, Xtro\pgm1, Xtro\scgn, Xtro\calml4, Xtro\pvalb.2, Xtro\tnnc2, Xtro\ocm, Xtro\pvalb, Xtro\efcab6, Xtro\ocm.2, Xtro\cabp4, Xtro\cabp7" "Mmus\Cabp5, Mmus\Calm2, Mmus\Efcab9, Mmus\Spata21, Mmus\Cabp2, Mmus\Cabp7, Mmus\Efcab6, Mmus\Tnnc2, Mmus\Calm4, Mmus\Scgn, Mmus\Efcab3, Mmus\Calm3, Mmus\Calm1, Mmus\1700023F06Rik, Mmus\Calb1, Mmus\Pvalb, Mmus\Efcab11, Mmus\Tnnc1, Mmus\Calml3, Mmus\Calb2, Mmus\Cabp1, Mmus\Caln1, Mmus\Efcab2, Mmus\Ocm, Mmus\Efcab7, Mmus\Calml4, Mmus\Cabp4, Mmus\Rhbdl3" "Hsap\PVALB, Hsap\EFCAB13, Hsap\SCGN, Hsap\OCM2, Hsap\TNNC2, Hsap\CALB1, Hsap\CABP7, Hsap\OCM, Hsap\EFCAB3, Hsap\CALB2, Hsap\CALN1, Hsap\CALML5, Hsap\CABP1, Hsap\CALM1, Hsap\CABP5, Hsap\CALML4, Hsap\CALML3, Hsap\EFCAB11, Hsap\CABP4, Hsap\EFCAB6, Hsap\CALM3, Hsap\RHBDL3, Hsap\CABP2, Hsap\CALML6, Hsap\EFCAB9, Hsap\SPATA21, Hsap\EFCAB2, Hsap\CALM2, Hsap\EFCAB7, Hsap\TNNC1" viable DRSC04552 E -0.04549876 0.134993878 3.02212232 0.245069034 -0.077724851 -1.168799764 FBgn0004937 ABO-X Abnormal Ooycte on X http://flybase.org/reports/FBgn0004937 - region - - - "ABO, ABO-X" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039102 SPE Spatzle-Processing Enzyme http://flybase.org/reports/FBgn0039102 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" innate immune response ; GO:0045087 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from mutant phenotype positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from direct assay zymogen activation ; GO:0031638 | inferred from direct assay response to fungus ; GO:0009620 | inferred from expression pattern defense response ; GO:0006952 | inferred from mutant phenotype humoral immune response ; GO:0006959 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred by curator from GO:0050832 "SPE, CG16705, c-SP4, CT37173, SP4, proPO-AE, Sp4, spe" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG16705 11-Aug-17 DroID_v2017_08 - - "Cele\try-1, Cele\try-3, Cele\svh-1, Cele\try-6" - - - "viable,partially lethal - majority live,heat sensitive,immune response defective,recessive,lethal,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval fat body,embryonic/larval hemocoel,trichogen cell" FBgn0261244 inaE inactivation no afterpotential E http://flybase.org/reports/FBgn0261244 protein_coding_gene lipoprotein lipase activity ; GO:0004465 | inferred from direct assay lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR002921 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "inaE, EP(X)1101, CG11102, CG11096, CG15761, CG11104, CG32630, CG33174, DAGL" "IPR002921:Fungal lipase-like domain, IPR029058:Alpha/Beta hydrolase fold" CG33174 11-Aug-17 DroID_v2017_08 "Drer\dagla, Drer\daglb" - Cele\dagl-2 Xtro\dagla "Mmus\Daglb, Mmus\Dagla" "Hsap\DAGLB, Hsap\DAGLA" FBgn0260319 GSd312 - http://flybase.org/reports/FBgn0260319 gene - - - GSd312 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0024507 33-13 33-13 http://flybase.org/reports/FBgn0024507 - gene - - - 33-13 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033236 CG14764 - http://flybase.org/reports/FBgn0033236 protein_coding_gene - - - "CG2923, CG14764" - CG14764 11-Aug-17 DroID_v2017_08 - - "Cele\H12I19.8, Cele\Y45G12C.1, Cele\Y27F2A.6, Cele\F41D3.9, Cele\F32B4.1, Cele\C16D9.4, Cele\R05A10.7, Cele\T15D6.9, Cele\C06B8.2, Cele\ZK1225.1, Cele\F46F5.10, Cele\C16D9.5, Cele\F28G4.3, Cele\F22E5.1, Cele\C16D9.3, Cele\F41D3.8, Cele\ZK1053.1" - - - viable FBgn0031117 GstT3 Glutathione S transferase T3 http://flybase.org/reports/FBgn0031117 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "cg1702, CG1702, GstT3, gstt3, GSTT3, DmGSTT3a, DmGSTT3b, GSTT3a, GSTT3b" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG1702 11-Aug-17 DroID_v2017_08 "Drer\gstt2, Drer\gstt1a, Drer\vars, Drer\gstt1b, Drer\sgsm2, Drer\gstr, Drer\eef1g, Drer\mars, Drer\sgsm1b, Drer\eef1e1" "Scer\TEF4, Scer\GTT1, Scer\YGR201C, Scer\CAM1, Scer\URE2, Scer\GTT2" "Cele\gst-29, Cele\gst-35, Cele\gst-21" "Xtro\gstt1, Xtro\eef1e1, Xtro\sgsm2, Xtro\sgsm1, Xtro\eef1g" "Mmus\Gstt3, Mmus\Eef1e1, Mmus\Sgsm2, Mmus\Sgsm1, Mmus\Gstt4, Mmus\Gstt1, Mmus\Gstt2, Mmus\Vars, Mmus\Mars, Mmus\Eef1g" "Hsap\VARS, Hsap\SGSM1, Hsap\EEF1G, Hsap\MARS, Hsap\EEF1E1, Hsap\GSTT2B, Hsap\SGSM2, Hsap\GSTT1, Hsap\GSTT2" FBgn0005478 l(1)ts1081 lethal (1) ts1081 http://flybase.org/reports/FBgn0005478 - gene - - - l(1)ts1081 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0065597 l(2)SH0882 lethal (2) SH0882 http://flybase.org/reports/FBgn0065597 gene - - - "l(2)SH0882, l(2)SH2 0882" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267148 CR45588 - http://flybase.org/reports/FBgn0267148 non_protein_coding_gene - - - CR45588 - CR45588 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264563 CG43935 - http://flybase.org/reports/FBgn0264563 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43935 - CG43935 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085526 CG40856 - http://flybase.org/reports/FBgn0085526 protein_coding_gene - - - CG40856 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004084 alphagamma-element alphagamma element http://flybase.org/reports/FBgn0004084 - non_protein_coding_gene - - - "alphabeta-element, 516/1, 0516/01, Hsralphagamma, alphagamma-element, Hsr alpha beta, alpha-beta" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially lethal - majority die,recessive" FBgn0011245 ms(2)29F male sterile (2) 29F http://flybase.org/reports/FBgn0011245 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(2)07717, ms(2)29F" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0065053 snoRNA:Me18S-C1831 - http://flybase.org/reports/FBgn0065053 snoRNA_gene - - - "Dm-737, snoR737, CR33674, snoRNA:Me18S-C1831, Me18S-C1831(SnoR737), snoRNA:737" - CR33674 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000121 Arr2 Arrestin 2 http://flybase.org/reports/FBgn0000121 - protein_coding_gene opsin binding ; GO:0002046 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with ninaE deactivation of rhodopsin mediated signaling ; GO:0016059 | traceable author statement metarhodopsin inactivation ; GO:0016060 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype metarhodopsin inactivation ; GO:0016060 | non-traceable author statement photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype adaptation of rhodopsin mediated signaling ; GO:0016062 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype metarhodopsin inactivation ; GO:0016060 | inferred from mutant phenotype inferred from genetic interaction with Arr1 desensitization of G-protein coupled receptor protein signaling pathway by arrestin ; GO:0002032 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype inferred from genetic interaction with Arr1 rhabdomere ; GO:0016028 | inferred from direct assay subrhabdomeral cisterna ; GO:0016029 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay rhabdomere ; GO:0016028 | colocalizes_with inferred from direct assay "arr2, ArrB-ml, PRI, ArrB, 49, CG5962, AH, Arr2, ARR2, Arr, arr, Arr-2, Dro.-Arr.II, DAII" "IPR014753:Arrestin, N-terminal, IPR014756:Immunoglobulin E-set, IPR000698:Arrestin, IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR017864:Arrestin, conserved site" CG5962 11-Aug-17 DroID_v2017_08 "Drer\saga, Drer\arrb1, Drer\sagb, Drer\arrb2b, Drer\arr3b, Drer\arr3a, Drer\arrb2a" - Cele\arr-1 "Xtro\arrb1, Xtro\arrb2, Xtro\sag, Xtro\arr3" "Mmus\Arr3, Mmus\Sag, Mmus\Arrb1, Mmus\Arrb2" "Hsap\SAG, Hsap\ARRB2, Hsap\ARRB1, Hsap\ARR3" adult stage rhabdomere

"neurophysiology defective,wild-type,auditory perception defective,viable" "ommatidium,retina,rhabdomere,photoreceptor cell,eye photoreceptor cell,eye,conditional,rhabdomere | conditional" FBgn0036080 Or67d Odorant receptor 67d http://flybase.org/reports/FBgn0036080 protein_coding_gene pheromone receptor activity ; GO:0016503 | inferred from mutant phenotype odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 response to pheromone ; GO:0019236 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from sequence or structural similarity with Or22a courtship behavior ; GO:0007619 | inferred from mutant phenotype detection of pheromone ; GO:0043695 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype cilium ; GO:0005929 | colocalizes_with inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 sensory dendrite ; GO:0071683 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "Or67d, 67d, CG14157, OR67d" "IPR004117:Olfactory receptor, insect" CG14157 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,neurophysiology defective,male,smell perception defective" "sensillum trichodeum of antennal segment 3,antennal trichoid sensillum at1" FBgn0001708 l(1)ESHS29 lethal (1) ESHS29 http://flybase.org/reports/FBgn0001708 - gene - - - l(1)ESHS29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259376 EP-880 - http://flybase.org/reports/FBgn0259376 gene - - - EP-880 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0085071 clh cliffhanger http://flybase.org/reports/FBgn0085071 gene - adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype - "D44, clh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "locomotor behavior defective,recessive" FBgn0262478 CG43068 - http://flybase.org/reports/FBgn0262478 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43068 - CG43068 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010124 l(1)HM25 lethal (1) of Helen Mayo http://flybase.org/reports/FBgn0010124 - gene - - - l(1)HM25 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0040027 CG17452 - http://flybase.org/reports/FBgn0040027 protein_coding_gene - - - CG17452 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035534 mRpS6 mitochondrial ribosomal protein S6 http://flybase.org/reports/FBgn0035534 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82931 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82932 structural constituent of ribosome ; GO:0003735 | traceable author statement small ribosomal subunit rRNA binding ; GO:0070181 | inferred from biological aspect of ancestor with PANTHER:PTN001077198 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82932 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:P82931 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82932 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82931 "MRP-S6, CG15016, BcDNA:RH10862, mRpS6, Mrps6" "IPR000529:Ribosomal protein S6, IPR014717:Translation elongation factor EF1B/ribosomal protein S6" CG15016 11-Aug-17 DroID_v2017_08 Drer\mrps6 Scer\MRP17 Cele\mrps-6 - Mmus\Mrps6 Hsap\MRPS6 "viable,visible" trichogen cell FBgn0000446 dhm dark hairy margins http://flybase.org/reports/FBgn0000446 - gene - - - dhm - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile,good" "scutellar bristle,wing,wing vein,abdomen & macrochaeta" FBgn0031849 CG11327 - http://flybase.org/reports/FBgn0031849 protein_coding_gene - - - CG11327 - CG11327 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266388 CR45028 - http://flybase.org/reports/FBgn0266388 non_protein_coding_gene - - - CR45028 - CR45028 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023004 l(3)s9999 lethal (3) s9999 http://flybase.org/reports/FBgn0023004 - gene - - - l(3)s9999 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002274 l(3)70Ab lethal (3) 70Ab http://flybase.org/reports/FBgn0002274 - gene - - - "l(3)ZF2, l(3)70Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065667 l(2)SH0694 lethal (2) SH0694 http://flybase.org/reports/FBgn0065667 gene - - - "l(2)SH0694, l(2)SH2 0694" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265786 CR44575 - http://flybase.org/reports/FBgn0265786 non_protein_coding_gene - - - "lincRNA.51, CR44575" - CR44575 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036306 CG10973 - http://flybase.org/reports/FBgn0036306 protein_coding_gene enzyme inhibitor activity ; GO:0004857 | inferred from biological aspect of ancestor with PANTHER:PTN001062464 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10973 "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR013918:Nucleotide exchange factor Fes1" CG10973 11-Aug-17 DroID_v2017_08 Drer\hspbp1 "Scer\SIL1, Scer\FES1" Cele\Y38E10A.22 Xtro\hspbp1 "Mmus\Sil1, Mmus\Hspbp1" "Hsap\SIL1, Hsap\HSPBP1" viable DRSC09813 I 1.942195018 -0.187883553 -0.705177909 0.745874932 -0.837870468 -0.1016987 FBgn0023026 l(2)FZ13 lethal (2) FZ13 http://flybase.org/reports/FBgn0023026 - gene - - - l(2)FZ13 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037421 CG15594 - http://flybase.org/reports/FBgn0037421 protein_coding_gene - - - CG15594 IPR012464:Protein of unknown function DUF1676 CG15594 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025630 Rtca RNA 3'-terminal phosphate cyclase http://flybase.org/reports/FBgn0025630 - protein_coding_gene RNA-3'-phosphate cyclase activity ; GO:0003963 | inferred from electronic annotation with InterPro:IPR017770 "RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR000228, InterPro:IPR017770 negative regulation of axon regeneration ; GO:0048681 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "EG:22E5.3, CG4061, RTC1_DROME, Rtca" "IPR000228:RNA 3'-terminal phosphate cyclase, IPR013791:RNA 3'-terminal phosphate cyclase, insert domain, IPR013792:RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta, IPR023797:RNA 3'-terminal phosphate cyclase domain, IPR017770:RNA 3'-terminal phosphate cyclase type 1" CG4061 11-Aug-17 DroID_v2017_08 "Drer\rcl1, Drer\rtca" Scer\RCL1 - "Xtro\rcl1, Xtro\rtca" "Mmus\Rtca, Mmus\Rcl1" "Hsap\RTCA, Hsap\RCL1" viable FBgn0060958 l(3)S033702a lethal (3) S033702a http://flybase.org/reports/FBgn0060958 gene - - - "0337/02, l(3)S033702a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033518 Prx2540-2 Peroxiredoxin 2540-2 http://flybase.org/reports/FBgn0033518 protein_coding_gene peroxiredoxin activity ; GO:0051920 | inferred from electronic annotation with InterPro:IPR019479 peroxidase activity ; GO:0004601 | inferred from direct assay "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 hydrogen peroxide catabolic process ; GO:0042744 | inferred from direct assay" cytosol ; GO:0005829 | inferred from direct assay "CG11765, DPx-2540-2, Prx2540, DPx2540, Prx2540-2" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR024706:Peroxiredoxin, AhpC-type, IPR013766:Thioredoxin domain" CG11765 11-Aug-17 DroID_v2017_08 "Drer\prdx4, Drer\prdx1, Drer\prdx3, Drer\prdx6, Drer\prdx2" "Scer\PRX1, Scer\TSA1, Scer\TSA2" "Cele\prdx-2, Cele\prdx-3, Cele\prdx-6" Xtro\prdx6 "Mmus\Prdx2, Mmus\Prdx4, Mmus\Prdx6b, Mmus\Prdx3, Mmus\Prdx6, Mmus\Prdx1" "Hsap\PRDX4, Hsap\PRDX2, Hsap\PRDX6, Hsap\PRDX1, Hsap\PRDX3" FBgn0033640 CG13198 - http://flybase.org/reports/FBgn0033640 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13198 IPR010512:Protein of unknown function DUF1091 CG13198 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069949 CG41074 - http://flybase.org/reports/FBgn0069949 protein_coding_gene - - - CG41074 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266258 CR44953 - http://flybase.org/reports/FBgn0266258 non_protein_coding_gene - - - "CR44953, lincRNA.895" - CR44953 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029038 l(2)I16 lethal (2) I16 http://flybase.org/reports/FBgn0029038 gene - - - "I16, l(2)I16" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069174 mcl(2)Z5838 mcl(2)Z5838 http://flybase.org/reports/FBgn0069174 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z5838 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0082184 l(3)e02803 lethal (3) e02803 http://flybase.org/reports/FBgn0082184 gene - - - l(3)e02803 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038659 EndoA Endophilin A http://flybase.org/reports/FBgn0038659 protein_coding_gene phospholipid binding ; GO:0005543 | inferred from direct assay lysophosphatidic acid acyltransferase activity ; GO:0042171 | inferred from direct assay synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle endocytosis ; GO:0048488 | traceable author statement regulation of synapse structure or activity ; GO:0050803 | inferred from mutant phenotype membrane tubulation ; GO:0097320 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "endo, Endo, Dendo-A, CG14296, D-endoA, D-endo, endoA, EndoA" "IPR001452:SH3 domain, IPR004148:BAR domain, IPR013315:Spectrin alpha chain, SH3 domain, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR028501:Endophilin-A" CG14296 11-Aug-17 DroID_v2017_08 "Drer\sh3gl3b, Drer\grb2a, Drer\stam, Drer\sh3gl1b, Drer\sh3gl3a, Drer\sh3gl2, Drer\stam2, Drer\grb2b, Drer\sh3gl1a" "Scer\HSE1, Scer\PIN3, Scer\BOI2, Scer\SYT1" "Cele\unc-57, Cele\stam-1, Cele\sem-5" "Xtro\sh3gl3, Xtro\sh3gl1, Xtro\sh3gl2, Xtro\grb2" "Mmus\Sh3gl1, Mmus\Sh3gl2, Mmus\Stam, Mmus\Sh3gl3, Mmus\Grb2, Mmus\Stam2" "Hsap\STAM2, Hsap\SH3GL3, Hsap\STAM, Hsap\SH3GL1, Hsap\SH3GL2, Hsap\GRB2" "viable,neuroanatomy defective,partially lethal - majority die,lethal,recessive,neurophysiology defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage,paralytic,lethal - all die before end of larval stage,some die during larval stage,developmental rate defective,germline clone,somatic clone,phototaxis defective" "NMJ bouton,supernumerary,synapse[-],presynaptic active zone[-],presynaptic active zone,presynaptic active zonern--14,eye,wing,ommatidium,interommatidial bristle,bouton,motor neuron,eye photoreceptor cell,somatic clone,eye photoreceptor cell & synaptic vesicle | somatic clone[-],synaptic vesicle[-],retina,embryonic/larval neuromuscular junction" FBgn0264671 wobbly-lumens wobbly lumens http://flybase.org/reports/FBgn0264671 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - wobbly-lumens - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0024534 l(3)L1170b lethal (3) L1170b http://flybase.org/reports/FBgn0024534 - gene - - - "l(3)L1170, l(3)L1170b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031675 CG9121 - http://flybase.org/reports/FBgn0031675 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001496 ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001194385 CG9121 "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR001496:SOCS box domain" CG9121 11-Aug-17 DroID_v2017_08 "Drer\rai14, Drer\ankrd24, Drer\uacaa, Drer\uacab" - "Cele\M60.7, Cele\mlt-2" "Xtro\rai14, Xtro\ankrd24, Xtro\uaca" "Mmus\Ankrd35, Mmus\Asb10, Mmus\Ankrd24, Mmus\Asb16, Mmus\Uaca, Mmus\Asb18, Mmus\Asb4, Mmus\Rai14" "Hsap\RAI14, Hsap\ASB4, Hsap\UACA, Hsap\ANKRD24, Hsap\ASB16, Hsap\ASB10, Hsap\ASB18, Hsap\ANKRD35" viable DRSC03142 I 1.74035333 -0.317514843 -0.666486795 -0.321002584 -0.296404468 -0.615194887 FBgn0052117 CG32117 - http://flybase.org/reports/FBgn0052117 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32117 - CG32117 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259533 GG01083 - http://flybase.org/reports/FBgn0259533 gene - - - GG01083 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,arista" FBgn0260068 2L2572 - http://flybase.org/reports/FBgn0260068 gene - - - 2L2572 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,viable,lethal" "embryonic/larval tracheal system,somatic clone" FBgn0022234 l(2)k02802 lethal (2) k02802 http://flybase.org/reports/FBgn0022234 - gene - - - l(2)k02802 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024284 Su(hh)2A Suppressor of hedgehog 2A http://flybase.org/reports/FBgn0024284 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "S(hh)2A, Su(hh)2A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005362 Sy Stubby http://flybase.org/reports/FBgn0005362 - gene - - - Sy - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "macrochaeta,humeral bristle,notopleural bristle" FBgn0034910 CG4763 - http://flybase.org/reports/FBgn0034910 protein_coding_gene - - - CG4763 - CG4763 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065110 ppk10 pickpocket 10 http://flybase.org/reports/FBgn0065110 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG34042, BP1007, PPK10, ppk10" IPR001873:Epithelial sodium channel CG34042 11-Aug-17 DroID_v2017_08 "Drer\asic1a, Drer\asic1b, Drer\asic4b, Drer\asic4a, Drer\asic1c, Drer\asic2" - "Cele\flr-1, Cele\acd-3, Cele\acd-4, Cele\acd-5, Cele\del-7, Cele\acd-1, Cele\acd-2, Cele\delm-1, Cele\delm-2" "Xtro\scnn1g, Xtro\scnn1d, Xtro\scnn1a, Xtro\asic1, Xtro\asic4, Xtro\scnn1b, Xtro\asic5" "Mmus\Asic4, Mmus\Asic3, Mmus\Asic5, Mmus\Scnn1a, Mmus\Scnn1b, Mmus\Asic1, Mmus\Scnn1g, Mmus\Asic2" "Hsap\SCNN1G, Hsap\ASIC3, Hsap\ASIC1, Hsap\ASIC4, Hsap\SCNN1B, Hsap\ASIC2, Hsap\SCNN1D, Hsap\SCNN1A, Hsap\ASIC5" viable FBgn0259865 Su(Ste):CR42434 Su(Ste):CR42434 http://flybase.org/reports/FBgn0259865 non_protein_coding_gene - - - "Su(Ste):CR42434, CR42434" - CR42434 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022372 Pt-26 Adult protein-26 http://flybase.org/reports/FBgn0022372 - gene - - - Pt-26 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031650 CG14044 - http://flybase.org/reports/FBgn0031650 protein_coding_gene - - - CG14044 - CG14044 11-Aug-17 DroID_v2017_08 - - Cele\cil-7 - - - FBgn0051638 CG31638 - http://flybase.org/reports/FBgn0051638 protein_coding_gene motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR002928 - myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR002928 "CG13764, CG9545, CG31638" IPR002928:Myosin tail CG31638 11-Aug-17 DroID_v2017_08 Drer\ccdc102a - Cele\F53F10.1 Xtro\ccdc102a Mmus\Ccdc102a "Hsap\CCDC102B, Hsap\CCDC102A, Hsap\CCDC158" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02269 IE 1.026565862 -2.205610785 0.754556429 -1.695466246 -1.384689286 -1.250418604 FBgn0260607 2L1809 - http://flybase.org/reports/FBgn0260607 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1809 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0029747 CG5062 - http://flybase.org/reports/FBgn0029747 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:17229 "BcDNA:AT13663, CG5062, FBgn0029747" IPR033253:Cilia- and flagella-associated protein 45 CG5062 11-Aug-17 DroID_v2017_08 Drer\cfap45 - - Xtro\cfap45 Mmus\Cfap45 Hsap\CFAP45 viable FBgn0025758 l(3)93DFd lethal (3) 93DFd http://flybase.org/reports/FBgn0025758 - gene - - - l(3)93DFd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041006 CG13302 - http://flybase.org/reports/FBgn0041006 protein_coding_gene - - - CG13302 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065751 l(2)SH0497 lethal (2) SH0497 http://flybase.org/reports/FBgn0065751 gene - - - "l(2)SH0497, l(2)SH2 0497" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036213 RpL10Ab Ribosomal protein L10Ab http://flybase.org/reports/FBgn0036213 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR002143 structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002143 maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype large ribosomal subunit ; GO:0015934 | inferred from electronic annotation with InterPro:IPR002143 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "RpL10Ab, CG7283, anon-EST:Posey188, BcDNA:RH06366, RpL10Ae, L10Ab, RpL10A" "IPR002143:Ribosomal protein L1, IPR016095:Ribosomal protein L1, 3-layer alpha/beta-sandwich, IPR028364:Ribosomal protein L1/ribosomal biogenesis protein, IPR023674:Ribosomal protein L1-like" CG7283 11-Aug-17 DroID_v2017_08 Drer\rpl10a "Scer\CIC1, Scer\TOS4, Scer\RPL1B, Scer\UTP30, Scer\RPL1A" "Cele\rpl-1, Cele\mrpl-1" Xtro\rpl10a "Mmus\Rpl10a, Mmus\Rsl1d1" "Hsap\RPL10A, Hsap\RSL1D1" "lethal,lethal - all die before end of larval stage" "follicle cell,germline clone,nucleus | germline clone,egg chamber,nucleolus | germline clone" DRSC10798 IEK -0.652374103 -2.206845515 1.887680279 -3.720063927 0.948899893 4.16742067 FBgn0267314 CR45750 - http://flybase.org/reports/FBgn0267314 non_protein_coding_gene - - - CR45750 - CR45750 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086253 rumi rumi http://flybase.org/reports/FBgn0086253 protein_coding_gene UDP-glucosyltransferase activity ; GO:0035251 | inferred from biological aspect of ancestor with PANTHER:PTN000954275 glucosyltransferase activity ; GO:0046527 | inferred from direct assay UDP-xylosyltransferase activity ; GO:0035252 | inferred from biological aspect of ancestor with PANTHER:PTN000954275 negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N Golgi organization ; GO:0007030 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with N protein O-linked glycosylation ; GO:0006493 | inferred from biological aspect of ancestor with PANTHER:PTN000258397 regulation of stem cell division ; GO:2000035 | inferred from mutant phenotype glycolipid metabolic process ; GO:0006664 | inferred from biological aspect of ancestor with PANTHER:PTN000258330 protein glycosylation in endoplasmic reticulum ; GO:0033577 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum lumen ; GO:0005788 | inferred from direct assay "rumi, CG17138, CG31152, Rumi, dRumi" IPR006598:Lipopolysaccharide-modifying protein CG31152 11-Aug-17 DroID_v2017_08 "Drer\kdelc2, Drer\poglut1, Drer\kdelc1" - - "Xtro\kdelc1, Xtro\kdelc2" "Mmus\Kdelc1, Mmus\Kdelc2, Mmus\Poglut1" "Hsap\POGLUT1, Hsap\KDELC2, Hsap\KDELC1" "viable,visible,body color defective,recessive,somatic clone,heat sensitive,temperature conditional,neuroanatomy defective,short lived,eclosion defective,partially lethal - majority die,lethal" "trichogen cell,mesothoracic tergum,chaeta,somatic clone,temperature conditional,microchaeta,heat sensitive,wing vein,enterocyte of posterior adult midgut epithelium,intestinal stem cell,supernumerary,wing margin,embryonic/larval neuron,notal microchaeta,leg,joint,mechanosensory chaeta" FBgn0027299 l(1)G0128 lethal (1) G0128 http://flybase.org/reports/FBgn0027299 - gene - - - l(1)G0128 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal,female" FBgn0035655 CG13291 - http://flybase.org/reports/FBgn0035655 protein_coding_gene - - - CG13291 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0243497 Gr21a::Orco - http://flybase.org/reports/FBgn0243497 engineered_fusion_gene - - - "Gr21a::Or83b, Gr21a::Orco" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040154 l(1)G0467 lethal (1) G0467 http://flybase.org/reports/FBgn0040154 gene - - - l(1)G0467 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0035256 CG13930 - http://flybase.org/reports/FBgn0035256 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium movement ; GO:0003341 | inferred from sequence or structural similarity with Dic61B axonemal dynein complex ; GO:0005858 | inferred from sequence or structural similarity with Dic61B CG13930 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG13930 11-Aug-17 DroID_v2017_08 Drer\wdr78 Scer\PFS2 Cele\prp-17 Xtro\wdr78 "Mmus\Wdr78, Mmus\Dnaic1" Hsap\WDR78 viable FBgn0037870 CG18577 - http://flybase.org/reports/FBgn0037870 protein_coding_gene - - - CG18577 - CG18577 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014260 l(2)N7-6 lethal (2) N7-6 http://flybase.org/reports/FBgn0014260 - gene - - - "N7-6, l(2)N7-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029726 CG15471 - http://flybase.org/reports/FBgn0029726 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15471 IPR018392:LysM domain CG15471 11-Aug-17 DroID_v2017_08 "Drer\lysmd3, Drer\lysmd1, Drer\lysmd4, Drer\lysmd2" - Cele\lmd-2 "Xtro\lysmd3, Xtro\lysmd4" "Mmus\Lysmd2, Mmus\Lysmd4, Mmus\Lysmd3, Mmus\Lysmd1" "Hsap\LYSMD1, Hsap\LYSMD4, Hsap\LYSMD3, Hsap\LYSMD2" viable DRSC18054 I -0.425731854 -1.852281866 -0.833618778 -0.662699746 -0.21790856 0.459405163 FBgn0264305 CG43783 - http://flybase.org/reports/FBgn0264305 protein_coding_gene lipid binding ; GO:0008289 | inferred from biological aspect of ancestor with PANTHER:PTN000336234 biological_process ; GO:0008150 | no biological data available endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000336234 endomembrane system ; GO:0012505 | inferred from direct assay "CG43783, CG5741, CG43113" IPR019411:MMM1 domain CG43783 11-Aug-17 DroID_v2017_08 "Drer\cpeb3, Drer\cpeb4, Drer\tex2l, Drer\cpeb1a, Drer\tex2" "Scer\MMM1, Scer\NVJ2" Cele\F55C12.5 "Xtro\cpeb4, Xtro\cpeb3, Xtro\cpeb2, Xtro\tex2.1" "Mmus\Tex2, Mmus\Cpeb3, Mmus\Cpeb4, Mmus\Cpeb2" "Hsap\TEX2, Hsap\CPEB4, Hsap\CPEB2, Hsap\CPEB3" FBgn0067877 Mod(Prat:bw)3-1 Mod(Prat:bw)3-1 http://flybase.org/reports/FBgn0067877 gene - - - "Mod-3-1, Mod(Prat:bw)3-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035901 CG6745 - http://flybase.org/reports/FBgn0035901 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001656, InterPro:IPR011760, InterPro:IPR020103 pseudouridine synthase activity ; GO:0009982 | inferred from biological aspect of ancestor with PANTHER:PTN000330437" pseudouridine synthesis ; GO:0001522 | inferred from biological aspect of ancestor with PANTHER:PTN000330437 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000330439 "CG6745, CT20937" "IPR001656:Pseudouridine synthase, TruD, IPR011760:Pseudouridine synthase, TruD, insertion domain, IPR020103:Pseudouridine synthase, catalytic domain" CG6745 11-Aug-17 DroID_v2017_08 "Drer\pus7l, Drer\pus7" Scer\PUS7 Cele\B0024.11 "Xtro\pus7, Xtro\pus7l" "Mmus\Pus7, Mmus\Pus7l" "Hsap\PUS7, Hsap\PUS7L" "partially lethal - majority die,some die during pupal stage" FBgn0023531 CG32809 - http://flybase.org/reports/FBgn0023531 "FBgn0025379, FBgn0025386, FBgn0052809" protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "EG:171E4.3, CG3791, CG3783, CG3737, EG:9D2.2, EG:73D1.1, CG32809" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR022782:Actin interacting protein 3, C-terminal" CG32809 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-278a6.1, Drer\si:ch211-285f17.1, Drer\zgc:114120, Drer\si:ch211-207d6.2" Scer\BUD6 Cele\Y71H2AM.15 "Xtro\srcin1, Xtro\kiaa1217" "Mmus\Srcin1, Mmus\Etl4" "Hsap\KIAA1217, Hsap\SRCIN1" viable FBgn0061130 l(3)S002501b lethal (3) S002501b http://flybase.org/reports/FBgn0061130 gene - - - "0025/01, l(3)S002501b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0000768 fs(1)A1042 female sterile (1) A1042 http://flybase.org/reports/FBgn0000768 - gene - - - "fs(1)1042ts, fs(1)A1042" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,mitotic cell cycle defective,lethal - all die before end of pupal stage,non-rescuable maternal effect,some die during pupal stage" blastoderm embryo FBgn0067065 Nrt::Wnt5 Nrt::Wnt5 http://flybase.org/reports/FBgn0067065 engineered_fusion_gene - - - Nrt::Wnt5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039250 Mink Mitotic spindle and nuclear protein http://flybase.org/reports/FBgn0039250 protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay establishment of mitotic spindle localization ; GO:0040001 | inferred from electronic annotation with InterPro:IPR026756 mitotic cytokinesis ; GO:0000281 | inferred from electronic annotation with InterPro:IPR026756 microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR026756 nucleus ; GO:0005634 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay "CG11120, Mink" IPR026756:Nucleolar and spindle-associated protein 1 CG11120 11-Aug-17 DroID_v2017_08 Drer\nusap1 - - - "Mmus\Nusap1, Mmus\Hmgn5" "Hsap\NUSAP1, Hsap\HMGN1" "viable,fertile" FBgn0031522 CG3285 - http://flybase.org/reports/FBgn0031522 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG3285 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG3285 11-Aug-17 DroID_v2017_08 "Drer\slc2a8, Drer\slc2a13b, Drer\slc2a12, Drer\LOC101882338, Drer\slc2a10, Drer\slc2a6" "Scer\HXT17, Scer\RGT2, Scer\ITR2, Scer\MAL11, Scer\MPH3, Scer\GAL2, Scer\GEX1, Scer\AZR1, Scer\HXT8, Scer\MAL31, Scer\GEX2, Scer\HXT15, Scer\STL1, Scer\MPH2, Scer\HXT7, Scer\VBA4, Scer\HXT1, Scer\YFL040W, Scer\HXT5, Scer\HXT16, Scer\YDR387C, Scer\HXT3, Scer\SNF3, Scer\ENB1, Scer\VBA5, Scer\VBA2, Scer\ITR1, Scer\YMR279C, Scer\HXT10, Scer\SGE1, Scer\HXT2, Scer\HXT13, Scer\HXT6, Scer\HXT14, Scer\HXT4, Scer\VBA1, Scer\HXT9, Scer\HXT11, Scer\VBA3, Scer\ATR1, Scer\YDL199C" - "Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a12" "Mmus\Slc2a8, Mmus\Slc2a13, Mmus\Slc2a10, Mmus\Slc2a12, Mmus\Slc2a6" "Hsap\SLC2A6, Hsap\SLC2A12, Hsap\SLC2A10, Hsap\SLC2A8, Hsap\SLC2A13" "viable,fertile" FBgn0025338 anon-58Fe anon-58Fe http://flybase.org/reports/FBgn0025338 - gene - - - "4-8, anon-58Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002877 mur murrey http://flybase.org/reports/FBgn0002877 - gene - - - mur - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile,eye color defective" "pigment cell,macrochaeta" FBgn0000684 flrdG flight reduced G http://flybase.org/reports/FBgn0000684 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdG - - 11-Aug-17 DroID_v2017_08 - - - - - - "jumping defective,locomotor behavior defective,flight defective" FBgn0024571 l(3)L7251 lethal (3) L7251 http://flybase.org/reports/FBgn0024571 - gene - - - l(3)L7251 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015820 Su(spl) Suppressor of split http://flybase.org/reports/FBgn0015820 - gene - - - Su(spl) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033235 CG8728 - http://flybase.org/reports/FBgn0033235 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000220169 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000220169 metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity with UniProtKB:Q10713 protein processing involved in protein targeting to mitochondrion ; GO:0006627 | inferred from biological aspect of ancestor with PANTHER:PTN000747147 protein processing ; GO:0016485 | inferred from sequence or structural similarity with UniProtKB:Q10713 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000747147 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q10713 CG8728 "IPR001431:Peptidase M16, zinc-binding site, IPR007863:Peptidase M16, C-terminal, IPR011765:Peptidase M16, N-terminal, IPR011249:Metalloenzyme, LuxS/M16 peptidase-like" CG8728 11-Aug-17 DroID_v2017_08 Drer\pmpca Scer\MAS2 Cele\mppa-1 Xtro\pmpca Mmus\Pmpca Hsap\PMPCA "viable,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0065759 l(2)SH0480 lethal (2) SH0480 http://flybase.org/reports/FBgn0065759 gene - - - "l(2)SH0480, l(2)SH2 0480" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044391 Scim37 Sensitized chromosome inheritance modifier 37 http://flybase.org/reports/FBgn0044391 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim37 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0266560 EP2269 - http://flybase.org/reports/FBgn0266560 gene - - - EP2269 - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval salivary gland FBgn0029961 Ir7a Ionotropic receptor 7a http://flybase.org/reports/FBgn0029961 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model sensory perception of taste ; GO:0050909 | inferred from expression pattern detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir7a, DmelIR7a, CG12663, IR7a" - CG12663 11-Aug-17 DroID_v2017_08 "Drer\grid1b, Drer\LOC100537813, Drer\grid1a" - Cele\glr-7 - "Mmus\Grid1, Mmus\Grik4" "Hsap\GRID2, Hsap\GRID1, Hsap\GRIN2C" viable FBgn0028059 l(3)S093909 lethal (3) S093909 http://flybase.org/reports/FBgn0028059 gene - - - "0939/09, l(3)S093909" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0046885 Gr98d Gustatory receptor 98d http://flybase.org/reports/FBgn0046885 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr98A1, CG12884, Gr98B1, 98B.1, GR98B.1, CG31061, Gr98d, GR98d" IPR013604:7TM chemoreceptor CG31061 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0065542 l(2)SH1058 lethal (2) SH1058 http://flybase.org/reports/FBgn0065542 gene - - - "l(2)SH1058, l(2)SH2 1058" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086407 BG01574 - http://flybase.org/reports/FBgn0086407 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01574 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0014188 har56 har56 http://flybase.org/reports/FBgn0014188 - gene - - - "har, Har56, har56" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0266739 CR45212 - http://flybase.org/reports/FBgn0266739 non_protein_coding_gene - - - CR45212 - CR45212 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029818 GAA1 Glycosylphosphatidylinositol anchor attachment 1 http://flybase.org/reports/FBgn0029818 protein_coding_gene - regulation of Golgi to plasma membrane protein transport ; GO:0042996 | inferred from mutant phenotype rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype attachment of GPI anchor to protein ; GO:0016255 | inferred from biological aspect of ancestor with PANTHER:PTN000329629 GPI-anchor transamidase complex ; GO:0042765 | inferred from biological aspect of ancestor with PANTHER:PTN000329629 endomembrane system ; GO:0012505 | inferred from direct assay "CG3033, GAA1" IPR007246:GPI transamidase component Gaa1 CG3033 11-Aug-17 DroID_v2017_08 Drer\gpaa1 Scer\GAA1 Cele\hpo-3 Xtro\gpaa1 Mmus\Gpaa1 Hsap\GPAA1 "lethal - all die before end of larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere,somatic clone" FBgn0023550 FarO Fatty acyl-CoA reductase in oenocytes http://flybase.org/reports/FBgn0023550 FBgn0029604 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from electronic annotation with InterPro:IPR026055 long-chain-fatty-acyl-CoA reductase activity ; GO:0050062 | inferred from direct assay negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype positive regulation of lipid storage ; GO:0010884 | inferred from mutant phenotype - "EG:103B4.2, CG18031, FarO" "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG18031 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" - Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR1, Hsap\FAR2" viable FBgn0027339 jim jim http://flybase.org/reports/FBgn0027339 "FBgn0016051, FBgn0024201, FBgn0037192, FBgn0064775" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - "CG11352, ovk, OVK, ovfc.K, BcDNA:SD14927, jim, Jim" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG11352 11-Aug-17 DroID_v2017_08 "Drer\znf865, Drer\si:dkey-261j4.5, Drer\LOC101883594, Drer\si:ch211-276c2.4, Drer\LOC101883230, Drer\si:ch211-198a12.6, Drer\LOC108179164, Drer\LOC103909987, Drer\im:7141269, Drer\LOC103911016, Drer\si:dkey-262g12.3, Drer\si: zfos-932h1.3, Drer\drl, Drer\si:ch73-299h12.9, Drer\zgc:174646, Drer\si:ch73-40a17.4, Drer\zgc:165514, Drer\si:ch211-222k6.2, Drer\LOC100333031, Drer\zbtb24, Drer\si:dkey-261j4.3, Drer\LOC100537317, Drer\LOC100538142, Drer\LOC100330167, Drer\wu:fe17e08, Drer\zgc:171673, Drer\si:ch211-155e24.3, Drer\LOC799968, Drer\LOC560148, Drer\zgc:112998, Drer\si:dkey-34m19.3, Drer\si:dkey-261j4.4, Drer\si:ch211-241b2.4" Scer\AZF1 "Cele\Y55F3AM.14, Cele\Y56A3A.28, Cele\scrt-1, Cele\che-1" - "Mmus\Zfp467, Mmus\Zfp11, Mmus\Zbtb24, Mmus\Zfp169, Mmus\Sall2, Mmus\Zfp729a, Mmus\Zfp748, Mmus\Zfp853, Mmus\Zfp715, Mmus\Zfp637, Mmus\Zfp712, Mmus\Zfp780b" "Hsap\ZNF133, Hsap\ZNF729, Hsap\ZNF629, Hsap\ZNF7, Hsap\ZNF546, Hsap\ZNF543, Hsap\ZNF530, Hsap\ZNF681, Hsap\ZNF595, Hsap\ZNF343, Hsap\ZNF32, Hsap\ZNF460, Hsap\ZNF708, Hsap\ZNF429, Hsap\ZNF84, Hsap\ZXDA, Hsap\ZNF853, Hsap\ZNF234, Hsap\ZNF99, Hsap\HKR1" " adult stage && oogenesis stage | stage >=S9 , adult stage && oogenesis stage | stage >=S10A , adult stage && oogenesis stage | stage >=S12 " " nurse follicle cell

, oocyte associated follicle cell

" " embryonic stage | stage 15 , adult stage && oogenesis stage | stage >=S10 , adult stage && oogenesis stage | stage >=S9 " " pharyngeal muscle

, oocyte associated follicle cell

, anterior embryonic/larval midgut

, nurse follicle cell

, embryonic/larval hindgut

" "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval hemocyte | third instar larval stage,dorsal multidendritic neuron ddaC" FBgn0259867 Su(Ste):CR42436 Su(Ste):CR42436 http://flybase.org/reports/FBgn0259867 non_protein_coding_gene - - - "Su(Ste):CR42436, CR42436" - CR42436 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030615 Cyp4s3 Cyp4s3 http://flybase.org/reports/FBgn0030615 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4s3, CG9081, Cyp4s3, RE63964" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG9081 11-Aug-17 DroID_v2017_08 "Drer\LOC100329425, Drer\cyp20a1, Drer\cyp46a1.3, Drer\cyp3c1, Drer\cyp3c3, Drer\cyp4v8, Drer\cyp4t8, Drer\cyp19a1b, Drer\cyp26a1, Drer\cyp46a1.2, Drer\cyp4v7, Drer\cyp26b1, Drer\cyp3c4, Drer\cyp4f3, Drer\cyp46a1.4, Drer\cyp3c2, Drer\cyp3a65, Drer\cyp26c1, Drer\cyp46a1.1, Drer\cyp19a1a" "Scer\ERG5, Scer\DIT2" "Cele\cyp-13A3, Cele\cyp-31A3, Cele\cyp-29A3, Cele\cyp-29A2, Cele\cyp-32A1, Cele\cyp-13A4, Cele\cyp-25A4, Cele\cyp-25A1, Cele\cyp-13A12, Cele\cyp-13A5, Cele\cyp-31A2, Cele\cyp-32B1, Cele\cyp-13A1, Cele\cyp-13A7, Cele\cyp-29A4, Cele\cyp-42A1, Cele\cyp-13A10, Cele\cyp-25A3, Cele\cyp-37A1, Cele\cyp-37B1, Cele\cyp-13A11, Cele\cyp-25A2, Cele\cyp-13A8" "Xtro\cyp4v2, Xtro\cyp19a1, Xtro\LOC100488227, Xtro\cyp20a1, Xtro\cyp4b1.2, Xtro\cyp26a1, Xtro\cyp4f2, Xtro\cyp4f22, Xtro\cyp4b1, Xtro\cyp26c1, Xtro\LOC100487918, Xtro\mgc108213, Xtro\cyp26b1" "Mmus\Cyp4f18, Mmus\Cyp3a57, Mmus\Cyp3a25, Mmus\Cyp3a59, Mmus\Cyp4a31, Mmus\Cyp26b1, Mmus\Cyp46a1, Mmus\Cyp4v3, Mmus\Cyp3a11, Mmus\Cyp26c1, Mmus\Cyp3a44, Mmus\Cyp26a1, Mmus\Cyp4a14, Mmus\Cyp4a10, Mmus\Cyp4f14, Mmus\Cyp4f15, Mmus\Cyp4f39, Mmus\Cyp19a1, Mmus\Cyp4a32, Mmus\Cyp4f37, Mmus\Cyp4x1, Mmus\Cyp4a12a, Mmus\Cyp3a16, Mmus\Cyp20a1, Mmus\Cyp4a12b, Mmus\Cyp4f40, Mmus\Cyp3a41b, Mmus\Cyp3a13, Mmus\Cyp4b1, Mmus\Cyp4f16, Mmus\Cyp4a30b, Mmus\Cyp3a41a, Mmus\Cyp4f17, Mmus\Cyp4a29, Mmus\Cyp4f13" "Hsap\CYP19A1, Hsap\CYP3A7, Hsap\CYP4Z1, Hsap\CYP4F11, Hsap\CYP4F2, Hsap\CYP20A1, Hsap\CYP4F3, Hsap\CYP46A1, Hsap\CYP4F8, Hsap\CYP3A5, Hsap\CYP4V2, Hsap\CYP3A4, Hsap\CYP4A11, Hsap\CYP4F22, Hsap\CYP4A22, Hsap\CYP4B1, Hsap\CYP26A1, Hsap\CYP26B1, Hsap\CYP4X1, Hsap\CYP4F12, Hsap\CYP3A43, Hsap\CYP26C1" "viable,fertile" FBgn0265538 CG44388 - http://flybase.org/reports/FBgn0265538 protein_coding_gene - - - "lincRNA.332, CR44388, CG44388" - CG44388 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038012 CG10013 - http://flybase.org/reports/FBgn0038012 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10013 IPR019193:Ubiquitin-conjugating enzyme E2-binding protein CG10013 11-Aug-17 DroID_v2017_08 Drer\ube3d Scer\YJR141W - Xtro\ube3d Mmus\Ube2cbp Hsap\UBE3D "viable,body color defective" mesothoracic tergum FBgn0037780 ohgt ohgata http://flybase.org/reports/FBgn0037780 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:30185 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:30185 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:30185 "ohgt, CG3925" "IPR034750:CULT domain, IPR003111:Lon, substrate-binding domain, IPR004910:Yippee/Mis18/Cereblon" CG3925 11-Aug-17 DroID_v2017_08 "Drer\crbn, Drer\si:ch211-51h9.7" - "Cele\R08B4.3, Cele\M18.6" Xtro\crbn Mmus\Crbn Hsap\CRBN viable DRSC30024 K -0.663151116 -0.434799196 -0.205782935 0.401584389 -0.09241333 1.665540493 FBgn0266356 CR45004 - http://flybase.org/reports/FBgn0266356 non_protein_coding_gene - - - CR45004 - CR45004 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037549 CG7878 - http://flybase.org/reports/FBgn0037549 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 helicase activity ; GO:0004386 | inferred from sequence or structural similarity RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "DmRH26, cg7878, CG7878" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG7878 11-Aug-17 DroID_v2017_08 Drer\ddx43 Scer\DBP2 "Cele\ddx-17, Cele\Y54G11A.3" Xtro\ddx43 "Mmus\Ddx43, Mmus\Ddx17" "Hsap\DDX53, Hsap\DDX17, Hsap\DDX43" "partially lethal - majority die,some die during pupal stage,viable,fertile" DRSC16330 E -0.692833852 -0.732993935 -1.917114001 0.448123068 0.412283112 1.415581724 FBgn0004217 l(3)84Fe lethal (3) 84Fe http://flybase.org/reports/FBgn0004217 - gene - - - l(3)84Fe - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259554 B2010 - http://flybase.org/reports/FBgn0259554 gene - - - B2010 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "unguis,leg" FBgn0060676 l(3)S077301 lethal (3) S077301 http://flybase.org/reports/FBgn0060676 gene - - - "0773/01, l(3)S077301" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025139 pll::Src64B pll::Src64B http://flybase.org/reports/FBgn0025139 - engineered_fusion_gene - - - "src-pll, pll::Src64B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001998 l(2)36Ab lethal (2) 36Ab http://flybase.org/reports/FBgn0001998 - gene - - - "l(2L)HT-6, l(2)HT-6, l(2)36Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015455 l(2)24CDb lethal (2) 24CDb http://flybase.org/reports/FBgn0015455 - gene - - - "l(2)g, l(2)24CDb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058103 CG40103 - http://flybase.org/reports/FBgn0058103 protein_coding_gene - - - CG40103 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085233 CG34204 - http://flybase.org/reports/FBgn0085233 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34204 - CG34204 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050321 CG30321 - http://flybase.org/reports/FBgn0050321 protein_coding_gene - - - CG30321 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" chaeta FBgn0013237 E(var)195 E(var)195 http://flybase.org/reports/FBgn0013237 - gene - - - "E-var(3)10, E(var)195" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0010287 Trf TBP-related factor http://flybase.org/reports/FBgn0010287 - protein_coding_gene "transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Brf TFIIB-class transcription factor binding ; GO:0001093 | inferred from physical interaction with TfIIB TFIIA-class transcription factor binding ; GO:0001092 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from direct assay core promoter sequence-specific DNA binding ; GO:0001046 | contributes_to inferred from physical interaction with Brf" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with UniProtKB:P27633 transcription from RNA polymerase III promoter ; GO:0006383 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from direct assay regulation of transcription from RNA polymerase III promoter ; GO:0006359 | inferred from direct assay transcription initiation from RNA polymerase III promoter ; GO:0006384 | inferred from expression pattern embryo development ; GO:0009790 | inferred from sequence or structural similarity with UniProtKB:P27633 nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with Brf polytene chromosome ; GO:0005700 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11588 inferred from sequence or structural similarity with SGD:S000000950 "TRF1, TRF, X70838, dTRF1, Trf1, CG7562, trf, Trf, dTRF-1" "IPR000814:TATA-box binding protein, IPR030491:TATA-box binding protein, conserved site, IPR033710:TATA-box binding protein, eukaryotic" CG7562 11-Aug-17 DroID_v2017_08 "Drer\tbpl1, Drer\tbp, Drer\tbpl2" Scer\SPT15 Cele\tbp-1 "Xtro\tbp, Xtro\tbpl1, Xtro\tbpl2" "Mmus\Tbpl1, Mmus\Tbpl2, Mmus\Tbp" "Hsap\TBP, Hsap\TBPL2, Hsap\TBPL1" " embryonic stage , spermatogenesis && adult stage " " supraesophageal ganglion

, testis

, embryonic central nervous system | restricted

, spermatocyte

" "male sterile,hyperactive,recessive,behavior defective,viable" "spermatozoon,spermatocyte" FBgn0070023 BG00489 BG00489 http://flybase.org/reports/FBgn0070023 gene - - - BG00489 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0014332 l(3)ry98 lethal (3) ry98 http://flybase.org/reports/FBgn0014332 - gene - - - l(3)ry98 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040012 CG17495 - http://flybase.org/reports/FBgn0040012 protein_coding_gene - - - CG17495 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052600 dpr8 defective proboscis extension response 8 http://flybase.org/reports/FBgn0052600 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "dpr8, Dpr-8, CT16867, CG5291, CG14415, CG11477, CG32600, Dpr8, dpr 8" "IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype" CG32600 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-264f5.6, Drer\si:ch211-163c2.2, Drer\LOC101885725, Drer\LOC100333196, Drer\si:dkey-65b12.12, Drer\LOC101885444" - Cele\zig-8 "Xtro\obsl1, Xtro\nfasc" Mmus\Amica1 - viable FBgn0033624 CG12384 - http://flybase.org/reports/FBgn0033624 protein_coding_gene death domain binding ; GO:0070513 | inferred from biological aspect of ancestor with PANTHER:PTN000323543 death domain binding ; GO:0070513 | inferred from sequence or structural similarity with HGNC:2672 "cellular response to amino acid starvation ; GO:0034198 | inferred from biological aspect of ancestor with PANTHER:PTN000323543 apoptotic process ; GO:0006915 | inferred from sequence or structural similarity with HGNC:2672 negative regulation of autophagy ; GO:0010507 | inferred from biological aspect of ancestor with PANTHER:PTN000323543 negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with HGNC:2672 apoptotic signaling pathway ; GO:0097190 | inferred from biological aspect of ancestor with PANTHER:PTN000323543" cellular_component ; GO:0005575 | no biological data available "BcDNA:GH16986, BcDNA:RH17411, CG12384" IPR024130:DAP1/DAPL1 CG12384 11-Aug-17 DroID_v2017_08 "Drer\dap1b, Drer\dap, Drer\LOC101885164" - "Cele\F54B8.4, Cele\T28F4.5" "Xtro\dapl1, Xtro\dap" "Mmus\Dapl1, Mmus\Dap" "Hsap\DAPL1, Hsap\DAP" viable FBgn0023526 CG2865 - http://flybase.org/reports/FBgn0023526 FBgn0066840 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay - "EG:25E8.4, anon-WO03040301.165, CG2865" IPR009263:SERTA domain CG2865 11-Aug-17 DroID_v2017_08 Drer\sertad4 - - - Mmus\Sertad4 Hsap\SERTAD4 pupal stage salivary gland

viable FBgn0262998 CR43306 - http://flybase.org/reports/FBgn0262998 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "CR43306, lincRNA.602" - CR43306 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035977 PGRP-LF Peptidoglycan recognition protein LF http://flybase.org/reports/FBgn0035977 protein_coding_gene "N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | inferred from electronic annotation with InterPro:IPR002502, InterPro:IPR006619, InterPro:IPR015510 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | non-traceable author statement peptidoglycan binding ; GO:0042834 | inferred from direct assay" "peptidoglycan catabolic process ; GO:0009253 | inferred from electronic annotation with InterPro:IPR002502, InterPro:IPR006619, InterPro:IPR015510 defense response to other organism ; GO:0098542 | inferred from mutant phenotype peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype antibacterial humoral response ; GO:0019731 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from direct assay negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with hep" integral component of plasma membrane ; GO:0005887 | non-traceable author statement inferred from direct assay "PGRP-like, CG4437, anon-WO0118547.581, PGRP-LF, PGRPLF, pgrp-lf" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein" CG4437 11-Aug-17 DroID_v2017_08 "Drer\pglyrp2, Drer\pglyrp5, Drer\pglyrp6" - - "Xtro\pglyrp2, Xtro\pglyrp1, Xtro\pglyrp1" "Mmus\Pglyrp1, Mmus\Pglyrp2, Mmus\Pglyrp4, Mmus\Pglyrp3" "Hsap\PGLYRP3, Hsap\PGLYRP4, Hsap\PGLYRP1" "visible,immune response defective,partially lethal - majority die,long lived" wing FBgn0083047 snoRNA:Psi18S-1377e snoRNA:Psi18S-1377e http://flybase.org/reports/FBgn0083047 snoRNA_gene - - - "snoRNA:Psi18S-1377e, Psi18S-1377e, psi18S-1377e, CR34625" - CR34625 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267575 CR45915 - http://flybase.org/reports/FBgn0267575 non_protein_coding_gene - - - CR45915 - CR45915 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052803 CG32803 - http://flybase.org/reports/FBgn0052803 protein_coding_gene - - - "CG14819, CG32803" - CG32803 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0011651 Mads-3 Mads-3 http://flybase.org/reports/FBgn0011651 - gene - - - Mads-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010718 l(3)00506 lethal (3) 00506 http://flybase.org/reports/FBgn0010718 - gene - - - "l(3)506, l(3)00506" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005108 GustS Gustatory S http://flybase.org/reports/FBgn0005108 - gene - - - GustS - - 11-Aug-17 DroID_v2017_08 - - - - - - taste perception defective taste bristle FBgn0013487 l(1)5PP10 lethal (1) 5PP10 http://flybase.org/reports/FBgn0013487 - gene - - - l(1)5PP10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect" embryonic segment & embryonic/first instar larval cuticle | germ-line clone FBgn0003731 Egfr Epidermal growth factor receptor http://flybase.org/reports/FBgn0003731 "FBgn0010599, FBgn0022793" protein_coding_gene "transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from electronic annotation with InterPro:IPR006211 protein domain specific binding ; GO:0019904 | inferred from electronic annotation with InterPro:IPR000308 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR006211, InterPro:IPR017441 protein binding ; GO:0005515 | inferred from physical interaction with Cbl, spri protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement epidermal growth factor-activated receptor activity ; GO:0005006 | inferred from sequence or structural similarity epidermal growth factor-activated receptor activity ; GO:0005006 | traceable author statement transmembrane signaling receptor activity ; GO:0004888 | traceable author statement" "transmembrane receptor protein tyrosine kinase signaling pathway=0007169 | inferred from electronic annotation with InterPro:IPR006211 protein phosphorylation=0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR006211, InterPro:IPR008266, InterPro:IPR020635 negative .. apoptotic signaling pathway=2001234 | with rpr maintenance of epithelial integrity, open tracheal system=0035160; stem cell fate commitment=0048865; oogenesis=0048477; border follicle cell migration=0007298; dorsal/ventral pattern formation=0009953; segment polarity determination=0007367; imaginal disc-derived wing morphogenesis=0007476; neurogenesis=0022008 | with Myc Malpighian tubule morphogenesis=0007443; blastoderm segmentation=0007350; oocyte dorsal/ventral axis specification=0007310; germ-band shortening=0007390; dorsal closure=0007391; ommatidial rotation=0016318; adult lifespan=0008340; branched duct epithelial cell fate determination, open tracheal system=0046845; border follicle cell migration=0007298; stomatogastric nervous system=0007421; oocyte anterior/posterior axis specification=0007314; wing vein specification=0007474; leg disc proximal/distal pattern formation=0007479; eye retinal cell programmed cell death=0046673; open tracheal system=0035277; mitotic cell cycle=0007346; haltere=0007482; Malpighian tubule morphogenesis=0061331; notum cell fate specification=0035310; apoptotic process=0043066; genital disc primordium=0035225; anterior/posterior pattern specification=0009952; wing vein morphogenesis=0008586; open tracheal system=0007424; chorion-containing eggshell pattern formation=0030381; muscle attachment=0016203; oenocyte differentiation=0001742; cone cell fate commitment=0042676; oocyte axis specification=0007309; border follicle cell migration=0007298; R7 cell differentiation=0045466; protein phosphorylation=0006468; R8 cell spacing in compound eye=0045468; tracheal pit formation in open tracheal system=0035202; wing and notum subfield formation=0035309; compound eye morphogenesis=0016330; glucose metabolic process=0010906; Malpighian tubule morphogenesis=0007443; compound eye retinal cell programmed cell death=0046673; leg disc proximal/distal pattern formation=0007479; G2/M transition of mitotic cell cycle=0000086; germ-line stem cell population maintenance=0030718; olfactory learning=0008355; wing vein morphogenesis=0008586; imaginal disc-derived wing morphogenesis=0007476; female germ-line cyst encapsulation=0048139; eye-antennal disc morphogenesis=0007455; G1/S transition of mitotic cell cycle=2000134; hemocyte differentiation=0045610; wing disc proximal/distal pattern formation=0007473; morphogenesis of follicular epithelium=0016333; R8 cell spacing in compound eye=0045468; imaginal disc=0007444; chorion-containing eggshell pattern formation=003038; antennal=0007469; wound healing=0090303; border follicle cell migration=0007298 | with Cbl with Pvr muscle cell fate specification=0042694; cell proliferation=0008284; compound eye photoreceptor fate commitment=0001752; cell projection assembly=0030031; dorsal appendage formation=0046843; male germ-line cyst encapsulation=0048140; signaling pathway=0007173; behavioral response to ethanol=0048149; wing disc morphogenesis=0007472 pattern specification=0009880; compound eye photoreceptor cell differentiation=0001751; second mitotic wave involved in compound eye morphogenesis=0016330; compound eye photoreceptor cell differentiation=0001751; compound eye morphogenesis=0001745; imaginal disc=0007444; apical/basal cell polarity=0035088 ..." cytoneme ; GO:0035230 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | traceable author statement "Egfr, egfr, Elp-B1, EGFR, DER, dEGFR, flb, der, d-egf-r, top, torpedo/egfr, EgfR, CG10079, EGF-R, DER/EGFR, Der, D-EGFR, dEGFR1, Egf-r, Elp, l(2)09261, Egf, EK2-6, c-erbB, DER/torpedo, DmHD-33, Elp-B1RB1, Elp-1, DER flb, top/DER, Torpedo/Egfr, D-Egf, Degfr, Torpedo/DER, torpedo/Egfr, EGFr, DER/top, l(2)05351, top/flb, l(2)57DEFa, l(2)57Ea, l(2)57EFa, HD-33, El, C-erb, EFG-R, degfr, EC2-4, DEGFR, EGfr, dEgfr, DER1, TOP, mor1, dEGFr, DEgfr, Tor, Flb" "IPR000494:Receptor L-domain, IPR000719:Protein kinase domain, IPR006211:Furin-like cysteine-rich domain, IPR006212:Furin-like repeat, IPR008266:Tyrosine-protein kinase, active site, IPR009030:Growth factor receptor cysteine-rich domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR032675:Leucine-rich repeat domain, L domain-like, IPR032778:Growth factor receptor domain 4, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR023409:14-3-3 protein, conserved site, IPR023410:14-3-3 domain, IPR000308:14-3-3 protein" CG10079 11-Aug-17 DroID_v2017_08 "Drer\erbb4a, Drer\tnk2b, Drer\erbb2, Drer\erbb3b, Drer\egfra, Drer\LOC571431, Drer\erbb3a, Drer\si:ch73-383l1.1, Drer\erbb4b" - "Cele\F57B9.8, Cele\gcy-2, Cele\let-23, Cele\gcy-14" "Xtro\erbb4, Xtro\erbb3, Xtro\ptk2b, Xtro\egfr" "Mmus\Fras1, Mmus\Egfr, Mmus\Erbb4, Mmus\Erbb3, Mmus\Erbb2" "Hsap\EGFR, Hsap\ERBB2, Hsap\ERBB4, Hsap\ERBB3" " embryonic stage | stage 17 && larval stage , adult stage , embryonic stage | stage 5, larval stage | third instar , larval stage , adult stage | male , oogenesis stage , larval stage | third instar && P-stage , embryonic stage | stage >7 , embryonic stage | stage >14 , embryonic stage , embryonic stage | 10-14hr , embryonic stage | stage 11-14 , embryonic stage | 24hr , pupal stage , embryonic stage | early-mid , embryonic stage | stage 6-7 , embryonic stage | stage 15,16 , embryonic stage | stage 4-5 , adult stage | female , pupal stage && adult stage , embryonic stage -- adult stage , embryonic stage | stage 17 " " embryonic/larval proventriculus

, adult brain cortex

,

, larval central nervous system | restricted

, dorsal mesothoracic disc

, oocyte

, ovary

, mesoderm

, embryonic/larval salivary gland

, eye disc

, larval brain

, eye-antennal disc

, embryonic/larval fat body

, morphogenetic furrow

, imaginal disc

, ventral midline

, larval outer optic anlage

, embryonic/larval posterior spiracle | presumptive

, morphogenetic furrow | anterior to

, larval inner optic anlage

,

ubiquitous , nurse cell

, Malpighian tubule | subset

, lamina

, ovary | anlagen

, testis | anlagen

, stomodeum

, proventriculus

, antennal disc

, larval brain | restricted

, adult hindgut | presumptive

, thoracico-abdominal ganglion

, ectoderm

, genital disc

, cephalic furrow

, follicle cell

, embryonic/larval midgut

, labral segment

, adult fat body

, adult foregut | presumptive

, embryonic/larval pharynx

, ventral midline glia | subset

, larval optic lobe

, embryonic telson | presumptive

, embryonic gnathal segment

" " larval stage | third instar , embryonic stage | mid-late , embryonic stage , embryonic stage | late , embryonic stage | mid , embryonic stage | stage 7 , embryonic stage | stage 11-14 " " morphogenetic furrow | posterior to

, lateral proliferation zone

, labral segment

, morphogenetic furrow

, epithelial cell && neuroblast

, muscle attachment site

, apodeme

, embryonic procephalic segment

, embryonic/larval hindgut

, embryonic/larval fat body

, morphogenetic furrow | anterior to

, embryonic/larval visceral muscle

, eye disc

, ectoderm

, imaginal disc

, embryonic mandibular segment

, epithelial cell

, pigment cell

, mesoderm

, ventral midline

, ventral midline glia | subset

, larval outer optic anlage

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,increased cell size,viable,dominant,wound healing defective,mitotic cell cycle defective,somatic clone,non-rescuable maternal effect,visual behavior defective,neuroanatomy defective,increased cell death,decreased cell number,cell polarity defective,female sterile,partially,maternal effect,heat sensitive,planar polarity defective,decreased cell size,lethal - all die before end of pupal stage,some die during pupal stage,cell lethalcell lethal,increased cell number,cell lethal,wild-type,germline clone,cell non-autonomous,semidominant,poor,hyperactive,size defective,conditional,small body,male limited,decreased cell death,learning defective,RU486 conditional,partially lethal - majority die,chemical sensitive,cell size defective,homeotic,chemical resistant,body color defective" "ventral histoblast nest abdominal,spiracular histoblast nest abdominal,adult cuticle,adult spiracle,chaeta,tergite,sternite,heart primordium,midline glial cell,eye,posterior wing margin,adult heart,adult heart muscle,myofilament,cardial cell,,wing vein,wing,embryonic/larval trachea,tracheal lumen,germarium,spectrosome,ommatidium,ventral nerve cord commissure,Malpighian tubule,dorsal closure embryo,extended germ band embryo,embryonic/larval salivary gland,embryonic head,eye disc,RP2 motor neuron,RP2sib neuron,photoreceptor cell,gonad,amnioserosa,embryonic/larval cuticle,embryonic/first instar larval cuticle,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,dorsal appendage,ocellus,macrochaeta,wing disc,submarginal cell,1st posterior cell,neuroblast,hindgut,posterior crossvein,sensory neuron,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,tracheal primordium,presumptive embryonic/larval tracheal system,tracheal branch primordium,ommatidial precursor cluster,dorsal air sac primordium,embryonic/larval posterior spiracle,lch5 neuron,embryonic cardioblast,ventral nerve cord primordium,embryonic/larval oenocyte,anterior crossvein,ventral furrow,egg,embryo,egg chamber,follicle cell,chorion,crossvein,mesothoracic tergum,head,bract,embryonic head epidermis,embryonic optic lobe primordium,optic lobe,embryonic stomatogastric nervous system,brain,corpus cardiacum primordium,Keilin's organ,abdominal ventral denticle belt,genital disc primordium,embryonic optic lobe,embryonic central brain,circumesophageal tract,abdominal lateral longitudinal muscle,abdominal dorsal acute muscle,abdominal ventral acute muscle,embryonic/larval somatic muscle,ventral thoracic disc primordium,embryonic/larval midgut,midgut constriction,endoderm,embryonic/larval muscle system,epidermis,Bolwig organ,anterior supraalar bristle,posterior supraalar bristle,posterior postalar bristle,anterior postalar bristle,anterior dorsocentral bristle,interface glial cell,metathoracic tibial transverse bristle row,prothoracic tibial transverse row bristle,leg,tarsal segment,morphogenetic furrow,spermatocyte,spermatid,spermatocyte cell spectrosome,cyst cell,germline stem cell,pale ommatidium,pretarsus,multidendritic neuron,ventral multidendritic neuron vdaB,cell cycle,embryonic/larval brain,oocyte,adult midgut precursor cell,hypostomal sclerite,cuticle,ventral midline,abdominal ventral monoscolopidial chordotonal organ,abdominal lateral pentascolopidial chordotonal organ,embryonic ventral epidermis,anterior dorsal histoblast nest abdominal,posterior dorsal histoblast nest abdominal,embryonic/larval dorsal trunk,embryonic/larval visceral branch,embryonic segment,intestinal stem cell,glial cell,adult brain,adult eye primordium,abdominal dorsal adult muscle precursor cell,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,anterior scutellar bristle,posterior scutellar bristle,A1-7 ventral acute muscle 2,ocellar bristle,filzkorper,stigmatophore,stomatogastric nervous system anlage,enterocyte,adult gut,midgut,wing blade,lamellocyte,cone cell,wing margin,wing hair,larval head,lch5 ligament attachment cell,embryonic epidermis,sensillum basiconicum,sensillum trichodeum,sensillum coeloconicum,optic cartridge,border follicle cell,wing cell,medial longitudinal fascicle,primary pigment cell,secondary pigment cell,tertiary pigment cell,dorsal oblique muscle,dorsal acute muscle,denticle,antenna,retina,eye-antennal disc,tibia,repo,motor neuron,presumptive embryonic/larval peripheral nervous system,fascicle,gastric caecum,embryonic/larval ganglionic branch,lamina monopolar neuron L1-L5,embryonic/larval brain,hemocyte,mesothoracic tibial bract,mesothoracic tibial apical bristle,prothoracic tibial apical bristle,capitellum,wing margin bristle,adult midgut precursor cell-prepupal stage P1,metathoracic tergum" DRSC04613 EK 0.341462121 -0.053537357 -0.125760172 -7.68610776 -5.771602562 -3.325739294 FBgn0000208 Bowed-d Bowed dominant http://flybase.org/reports/FBgn0000208 - gene - - - "Bow, Bowed-d, Bowed" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "wing,scutellar bristle,macrochaeta" FBgn0002192 l(3)63Bc lethal (3) 63Bc http://flybase.org/reports/FBgn0002192 - gene - - - l(3)63Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,sterile" FBgn0020655 ArfGAP1 ADP-ribosylation factor GTPase activating protein 1 http://flybase.org/reports/FBgn0020655 - protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 GTPase activator activity ; GO:0005096 | inferred from sequence model regulation of ARF protein signal transduction ; GO:0032012 | inferred from genetic interaction with garz regulation of GTPase activity ; GO:0043087 | inferred from sequence model Golgi stack ; GO:0005795 | inferred from genetic interaction with garz "i51, CG4237, GAP69C, ARF1-GAP, dArf1-GAP, gap69, Gap69c, ARF1GAP, arf1GAP, GAP, ArfGAP1, Gap69C, AG1" IPR001164:Arf GTPase activating protein CG4237 11-Aug-17 DroID_v2017_08 Drer\arfgap1 "Scer\GLO3, Scer\GCS1, Scer\SPS18" Cele\K02B12.7 Xtro\arfgap1 Mmus\Arfgap1 Hsap\ARFGAP1 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum,rhabdomereGMR.PF,eye photoreceptor cell,secondary lobe of embryonic/larval lymph gland | third instar larval stage,posterior signalling centre of lymph gland primary lobe | third instar larval stage,cortical zone of lymph gland primary lobe | third instar larval stage,plasmatocyte | third instar larval stage,crystal cell | third instar larval stage" FBgn0025769 l(3)89Cg lethal (3) 89Cg http://flybase.org/reports/FBgn0025769 - gene - - - "l(3)M191, l(3)89Cg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011668 Mst57Da Male-specific RNA 57Da http://flybase.org/reports/FBgn0011668 "FBgn0002859, FBgn0039377, FBgn0063235" protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response ; GO:0006952 | inferred from sequence or structural similarity oviposition ; GO:0018991 | non-traceable author statement post-mating behavior ; GO:0045297 | non-traceable author statement extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | non-traceable author statement "CG9074, bs30d07.y1, mst-1, mst(2)ag-1, Mst57D, BcDNA:GH19893, Mst57Da, mst57D" - CG9074 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014150 dpp::Hsap\BMP4 dpp::Hsap\BMP4 http://flybase.org/reports/FBgn0014150 - engineered_fusion_gene - - - dpp::Hsap\BMP4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040849 Ir41a Ionotropic receptor 41a http://flybase.org/reports/FBgn0040849 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir41a, CG17587, CG33492, IR41a, DmelIR41a" - CG33492 11-Aug-17 DroID_v2017_08 "Drer\LOC100334689, Drer\grid1b, Drer\LOC100537813, Drer\grid1a, Drer\grik2, Drer\grik5, Drer\grid2" - "Cele\glr-6, Cele\glr-3, Cele\F59E12.8" - "Mmus\Grid1, Mmus\Grik2, Mmus\Grik3, Mmus\Grik5, Mmus\Grid2" "Hsap\GRIK3, Hsap\GRIK2, Hsap\GRID1, Hsap\GRIK5, Hsap\GRID2" DRSC04875 K 0.925998956 0.157427659 0.776383293 0.481092686 2.049755131 0.905400238 FBgn0039260 Smg6 Smg6 http://flybase.org/reports/FBgn0039260 protein_coding_gene endoribonuclease activity ; GO:0004521 | inferred from sequence or structural similarity with UniProtKB:Q86US8 ribonucleoprotein complex binding ; GO:0043021 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 telomeric DNA binding ; GO:0042162 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 telomerase RNA binding ; GO:0070034 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 ribonuclease activity ; GO:0004540 | inferred from direct assay "regulation of RNA stability ; GO:0043487 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from direct assay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from direct assay synapse organization ; GO:0050808 | inferred from direct assay gene silencing by miRNA ; GO:0035195 | NOT inferred from mutant phenotype telomere maintenance via telomerase ; GO:0007004 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 RNA interference ; GO:0016246 | NOT inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000403280" telomerase holoenzyme complex ; GO:0005697 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000403280 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:Q86US8 "SMG6, CG6369, Smg6, dSMG6" "IPR018834:DNA/RNA-binding domain, Est1-type, IPR011990:Tetratricopeptide-like helical domain, IPR002716:PIN domain, IPR029060:PIN domain-like" CG6369 11-Aug-17 DroID_v2017_08 "Drer\smg5, Drer\swt1, Drer\smg6" "Scer\SWT1, Scer\EBS1, Scer\EST1" Cele\smg-6 - "Mmus\Swt1, Mmus\Smg6" "Hsap\SMG6, Hsap\SWT1" "partially lethal - majority live,lethal,viable,decreased cell number,somatic clone,neurophysiology defective,partially lethal - majority die" "eye,somatic clone" DRSC27703 IK -1.681595537 -0.716966242 -0.685070069 -0.440384161 -1.375684257 -2.085949291 FBgn0037835 CG14687 - http://flybase.org/reports/FBgn0037835 protein_coding_gene myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis - - "BcDNA:RE74890, CG14687" "IPR000048:IQ motif, EF-hand binding site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG14687 11-Aug-17 DroID_v2017_08 "Drer\spa17, Drer\nrgna, Drer\gap43" - "Cele\ZK1320.13, Cele\F39H12.3" Xtro\spa17 "Mmus\Gap43, Mmus\Spa17, Mmus\Nrgn, Mmus\Cabyr" "Hsap\NRGN, Hsap\SPA17, Hsap\GAP43" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC14910 IE -0.377322513 1.541389552 1.585917986 0.440490847 -1.038253257 -0.442690875 FBgn0264264 CR43764 - http://flybase.org/reports/FBgn0264264 non_protein_coding_gene - - - CR43764 - CR43764 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041609 anon-23Ac anon-23Ac http://flybase.org/reports/FBgn0041609 gene - - - anon-23Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045043 fs(1)60 female sterile (1) 60 http://flybase.org/reports/FBgn0045043 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)60 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg,ovary" FBgn0021961 l(2)k10113 lethal (2) k10113 http://flybase.org/reports/FBgn0021961 FBgn0043374 gene - - - "EP1221, l(2)k10113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible" "eye,dorsocentral bristle,scutellar bristle,tormogen cell,embryonic/larval salivary gland" FBgn0031735 CG11029 - http://flybase.org/reports/FBgn0031735 protein_coding_gene lipase activity ; GO:0016298 | inferred from electronic annotation with InterPro:IPR008265 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR008265 - CG11029 "IPR001087:GDSL lipase/esterase, IPR008265:Lipase, GDSL, active site, IPR013830:SGNH hydrolase-type esterase domain" CG11029 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-177p2.18, Drer\si:ch211-214p16.3" - "Cele\F13H8.11, Cele\F36A2.9, Cele\W02B12.1, Cele\Y73B6BL.37, Cele\T19D7.7, Cele\F09C8.1, Cele\Y40B10A.9, Cele\R07B7.9, Cele\R07B7.8, Cele\Y65B4BR.1" "Xtro\LOC100492667, Xtro\plb1" Mmus\Plb1 Hsap\PLB1 viable FBgn0001400 l(1)2Fc lethal (1) 2Fc http://flybase.org/reports/FBgn0001400 - gene - - - "l46, HF330, N12, l(1)N9, N7, l(1)N12, l(1)2Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone" "ovary,egg,germline clone" FBgn0264327 CR43786 - http://flybase.org/reports/FBgn0264327 non_protein_coding_gene - - - "CR43786, CG43786" - CR43786 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034783 CG9825 - http://flybase.org/reports/FBgn0034783 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 CG9825 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG9825 11-Aug-17 DroID_v2017_08 "Drer\ppt1, Drer\slc17a8, Drer\slc17a6a, Drer\slc17a7a, Drer\slc17a6b, Drer\slc17a5, Drer\slc17a9a, Drer\si:ch1073-513e17.1" "Scer\THI73, Scer\RSA1, Scer\DAL5, Scer\TNA1, Scer\YIL166C, Scer\RPA34" "Cele\T22F3.10, Cele\Y19D10A.8, Cele\F56A4.12, Cele\Y4C6B.3, Cele\F59A1.13, Cele\T02B11.6, Cele\F56A4.10, Cele\T22F3.11, Cele\slc-17.1, Cele\slc-17.3, Cele\T27D12.1, Cele\Y19D10A.11, Cele\T19D12.10, Cele\Y19D10A.4, Cele\Y51B9A.6, Cele\C18D1.2, Cele\T19D12.9, Cele\slc-17.2, Cele\slc-17.5, Cele\vglu-3, Cele\F44E7.7, Cele\Y4C6B.4, Cele\W04C9.6, Cele\H11E01.2, Cele\F10C2.7, Cele\D1046.4, Cele\C18H9.5, Cele\R10D12.1, Cele\F11A5.9, Cele\T01H3.3, Cele\slc-17.8, Cele\eat-4, Cele\Y19D10A.5, Cele\T22F3.8, Cele\M117.1, Cele\T22F3.7, Cele\T28H11.8, Cele\C01B4.7, Cele\slc-17.4, Cele\M162.5, Cele\cima-1, Cele\slc-17.9, Cele\C39E9.7, Cele\C01B4.8, Cele\F41C3.2, Cele\K11G9.5, Cele\Y15E3A.4, Cele\C35A5.3, Cele\K08C7.1, Cele\vglu-2" Xtro\slc17a7 "Mmus\Slc17a7, Mmus\Slc17a3, Mmus\Slc17a2, Mmus\Slc17a8, Mmus\Slc17a4, Mmus\Slc17a6, Mmus\Slc17a1, Mmus\Slc17a5" "Hsap\SLC17A2, Hsap\SLC17A7, Hsap\SLC17A6, Hsap\SLC17A1, Hsap\SLC17A5, Hsap\TCOF1, Hsap\SLC17A8, Hsap\SLC17A3, Hsap\SLC17A4" viable FBgn0259595 B1267 - http://flybase.org/reports/FBgn0259595 gene - - - B1267 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0042633 l(3)S134408b lethal (3) S134408b http://flybase.org/reports/FBgn0042633 gene - - - "l(3)134408, 1344/08, l(3)S134408, l(3)S134408b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0045483 Gr59a Gustatory receptor 59a http://flybase.org/reports/FBgn0045483 protein_coding_gene taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity with Gr5a sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 "CG30189, CG13537, Gr59a, GR59C.1, GR59a" IPR013604:7TM chemoreceptor CG30189 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028350 l(1)G0173 lethal (1) G0173 http://flybase.org/reports/FBgn0028350 gene - - - l(1)G0173 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0003231 ref(2)P refractory to sigma P http://flybase.org/reports/FBgn0003231 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 identical protein binding ; GO:0042802 | inferred from biological aspect of ancestor with PANTHER:PTN000387090 ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000387090 sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000387090 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype positive regulation of macroautophagy ; GO:0016239 | inferred from biological aspect of ancestor with PANTHER:PTN000387090 cytoplasm ; GO:0005737 | inferred from direct assay autophagosome ; GO:0005776 | inferred from direct assay aggresome ; GO:0016235 | inferred from biological aspect of ancestor with PANTHER:PTN000387090 "ref(2)P, Ref(2)P, Ref2P, Ref(2)p, ref2p, ref(2)p, ref(2)Po2, ref(2)Pn, ref, CG10360, p62, SQSTM1, p63, p62/Ref(2)P, Ref(2)P/p62, Ref2p" "IPR015940:Ubiquitin-associated domain, IPR000270:PB1 domain, IPR000433:Zinc finger, ZZ-type, IPR009060:UBA-like, IPR033741:Sequestosome-1, UBA domain" CG10360 11-Aug-17 DroID_v2017_08 Drer\sqstm1 - "Cele\C06G3.6, Cele\sqst-2, Cele\sqst-1, Cele\sqst-3, Cele\sqst-4" - Mmus\Sqstm1 Hsap\SQSTM1 " adult stage , adult stage | female " ovary

"short lived,stress response defective,locomotor behavior defective,male sterile" "Nebenkern,mitochondrial derivative,indirect flight muscle,mitochondrion,mitochondrial derivativePod2),mitochondrial derivativePod3)" FBgn0061123 l(3)S004019b lethal (3) S004019b http://flybase.org/reports/FBgn0061123 gene - - - "0040/19, l(3)S004019b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0051484 CG31484 - http://flybase.org/reports/FBgn0051484 protein_coding_gene - - - "CG2337, CG31484" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265936 Ada2a::Ada2b - http://flybase.org/reports/FBgn0265936 engineered_fusion_gene - - - Ada2a::Ada2b - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036180 Duba - http://flybase.org/reports/FBgn0036180 protein_coding_gene Lys63-specific deubiquitinase activity ; GO:0061578 | inferred from direct assay thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:25402 phagocytosis ; GO:0006909 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:25402 sperm individualization ; GO:0007291 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "ped, Q9VTK7, Duba, CG6091" "IPR003323:OTU domain, IPR003903:Ubiquitin interacting motif, IPR031084:OTU domain-containing protein 5/Otubain-like deubiquitinase 1" CG6091 11-Aug-17 DroID_v2017_08 "Drer\otud5a, Drer\otud5b, Drer\otud3" - "Cele\otub-4, Cele\otub-3" "Xtro\otud5, Xtro\otud3, Xtro\otud4" "Mmus\Otud4, Mmus\Otud5, Mmus\Otud3" "Hsap\OTUD1, Hsap\ALG13, Hsap\OTUD4, Hsap\OTUD5, Hsap\OTUD3" "viable,visible" trichogen cell FBgn0000539 E(B) Enhancer of Bar http://flybase.org/reports/FBgn0000539 - gene - - - "Eb, i, I, E(B)" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020637 Lcp65Ag2 Lcp65Ag2 http://flybase.org/reports/FBgn0020637 "FBgn0002539, FBgn0064908" protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence or structural similarity structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Lcp-g2, LCP8, L[[3]]CP8, Lcp8, DCP8-beta, CG10534, BcDNA:RE01644, Lcp65Ag2, chr3L:6106987..6107153" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG10534 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " pupal stage | 7-13 hr , larval stage , embryonic stage " FBgn0263870 CR43717 - http://flybase.org/reports/FBgn0263870 non_protein_coding_gene - - - CR43717 - CR43717 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069317 X-185-37 X-185-37 http://flybase.org/reports/FBgn0069317 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-185-37 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect" FBgn0036749 CG7460 - http://flybase.org/reports/FBgn0036749 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" - CG7460 "IPR002937:Amine oxidase, IPR023753:FAD/NAD(P)-binding domain" CG7460 11-Aug-17 DroID_v2017_08 "Drer\paox1, Drer\kdm1a, Drer\smox, Drer\zgc:66484, Drer\si:dkey-275b16.2" Scer\FMS1 "Cele\amx-3, Cele\amx-1, Cele\hpo-15" "Xtro\kdm1a, Xtro\smox, Xtro\paox, Xtro\LOC100145496" "Mmus\Kdm1b, Mmus\Smox, Mmus\Kdm1a, Mmus\Maob, Mmus\Paox" "Hsap\SMOX, Hsap\PAOX, Hsap\MAOB, Hsap\KDM1B, Hsap\KDM1A" viable FBgn0024819 Cbf-1 copia binding factor 1 http://flybase.org/reports/FBgn0024819 - gene - - - "CBF-1, Cbf-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028695 Rpn1 Regulatory particle non-ATPase 1 http://flybase.org/reports/FBgn0028695 protein_coding_gene enzyme regulator activity ; GO:0030234 | inferred from electronic annotation with InterPro:IPR016643 zinc ion binding ; GO:0008270 | inferred from direct assay regulation of protein catabolic process ; GO:0042176 | inferred from electronic annotation with InterPro:IPR016643 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype "proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9559 inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000001069 proteasome complex ; GO:0000502 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from direct assay" "p97, CG7762, BcDNA:LD21723, Rpn1, S2, RPN1" "IPR016024:Armadillo-type fold, IPR016643:26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit, IPR002015:Proteasome/cyclosome repeat, IPR011989:Armadillo-like helical" CG7762 11-Aug-17 DroID_v2017_08 Drer\psmd2 Scer\RPN1 Cele\rpn-1 Xtro\psmd2 Mmus\Psmd2 Hsap\PSMD2 lethal DRSC11274 IEK -2.47427163 -3.052800215 -2.60410134 -0.796476486 3.96492453 0.050076155 FBgn0038506 CG5860 - http://flybase.org/reports/FBgn0038506 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 - "FBgn0038506, CG5860" "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG5860 11-Aug-17 DroID_v2017_08 "Drer\ren, Drer\zgc:103530, Drer\zgc:63831, Drer\ctsd, Drer\nots" "Scer\BAR1, Scer\MKC7, Scer\YPS6, Scer\YGL258W-A, Scer\YPS1, Scer\PEP4, Scer\YPS7, Scer\YPS3, Scer\YPS5" "Cele\asp-5, Cele\asp-8, Cele\asp-14, Cele\asp-15, Cele\asp-7, Cele\asp-6, Cele\asp-18, Cele\asp-3, Cele\asp-16, Cele\asp-9, Cele\asp-2, Cele\asp-12, Cele\asp-10, Cele\asp-13, Cele\asp-4, Cele\asp-1, Cele\asp-17, Cele\asp-19" "Xtro\LOC496913, Xtro\ren, Xtro\pga4, Xtro\mgc108380, Xtro\ctsd, Xtro\bace2, Xtro\bace1, Xtro\pgc, Xtro\napsa, Xtro\ctse" "Mmus\Ctse, Mmus\Ctsd, Mmus\Bace2, Mmus\Pga5, Mmus\Ren1, Mmus\Ren2, Mmus\Napsa, Mmus\Cym, Mmus\Bace1, Mmus\Pgc" "Hsap\PGA3, Hsap\BACE1, Hsap\PGC, Hsap\NAPSA, Hsap\PGA4, Hsap\PGA5, Hsap\CTSE, Hsap\CTSD, Hsap\REN, Hsap\BACE2" viable FBgn0060463 l(3)SzB63Cd lethal (3) SzB63Cd http://flybase.org/reports/FBgn0060463 gene - - - "1154/15, l(3)S115415a, l(3)SzB63Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052722 CR32722 - http://flybase.org/reports/FBgn0052722 non_protein_coding_gene - - - CR32722 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265532 CR44382 - http://flybase.org/reports/FBgn0265532 non_protein_coding_gene - - - CR44382 - CR44382 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259980 ms(2)35Bj male sterile (2) 35Bj http://flybase.org/reports/FBgn0259980 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(2)35Bj - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0051975 CG31975 - http://flybase.org/reports/FBgn0051975 protein_coding_gene - - - "CG18501, CG31975" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG31975 11-Aug-17 DroID_v2017_08 - - "Cele\H06H21.8, Cele\nhr-246, Cele\dhs-27, Cele\C29F7.1, Cele\F59B1.8, Cele\F59B1.10, Cele\C29F7.2" - - - FBgn0030283 CG15198 - http://flybase.org/reports/FBgn0030283 protein_coding_gene - - - CG15198 - CG15198 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033357 Tom7 Translocase of outer membrane 7 http://flybase.org/reports/FBgn0033357 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:Q9P0U1 protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001754335 protein import into mitochondrial outer membrane ; GO:0045040 | inferred from biological aspect of ancestor with PANTHER:PTN001754335 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q9P0U1 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN001754335 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from biological aspect of ancestor with PANTHER:PTN001754335 integral component of mitochondrial outer membrane ; GO:0031307 | inferred from biological aspect of ancestor with PANTHER:PTN001754335 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from sequence or structural similarity with UniProtKB:Q9P0U1 "CG8226, dtom7, BcDNA:AT23266, Tom7" IPR012621:Mitochondrial import receptor subunit TOM7 CG8226 11-Aug-17 DroID_v2017_08 Drer\tomm7 Scer\TOM7 Cele\tomm-7 Xtro\tomm7 Mmus\Tomm7 Hsap\TOMM7 viable FBgn0003381 sh-5 short 5 http://flybase.org/reports/FBgn0003381 - gene - - - "sh5, sh-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing vein L5,wing vein L3" FBgn0033593 Listericin Listericin http://flybase.org/reports/FBgn0033593 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from expression pattern positive regulation of peptidoglycan recognition protein signaling pathway ; GO:0061059 | inferred from genetic interaction with PGRP-LE extracellular space ; GO:0005615 | inferred from direct assay "146991_at, BcDNA:RH62530, Listericin, CG9080" - CG9080 11-Aug-17 DroID_v2017_08 - - Cele\Y39A3B.7 - - - viable FBgn0069935 CG41114 - http://flybase.org/reports/FBgn0069935 protein_coding_gene - - - CG41114 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038479 CG17477 - http://flybase.org/reports/FBgn0038479 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH174, CG17477" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG17477 11-Aug-17 DroID_v2017_08 Drer\zmp:0000001088 - "Cele\try-1, Cele\svh-1, Cele\nhl-3" - "Mmus\Klk14, Mmus\Egfbp2, Mmus\Prss55, Mmus\Klk15" Hsap\KLK14 viable FBgn0265847 CR44636 - http://flybase.org/reports/FBgn0265847 non_protein_coding_gene - - - CR44636 - CR44636 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016890 l(2)39DEo lethal (2) 39DEo http://flybase.org/reports/FBgn0016890 - gene - - - "L138, l(2)39DEo" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000893 fs(1)M93 female sterile (1) M93 http://flybase.org/reports/FBgn0000893 - gene - - - fs(1)M93 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0067755 l(1)G0082 lethal (1) G0082 http://flybase.org/reports/FBgn0067755 gene - - - l(1)G0082 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0038089 d-cup davis-cup http://flybase.org/reports/FBgn0038089 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" - - "d-cup, CG14387" "IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain" CG14387 11-Aug-17 DroID_v2017_08 "Drer\efcab1, Drer\LOC100536377, Drer\tescb, Drer\ppp3r1b, Drer\ppp3r1a, Drer\chp2, Drer\chp1, Drer\tesca" Scer\CNB1 - "Xtro\cib1, Xtro\chp1, Xtro\ppp3r1, Xtro\efcab1" "Mmus\Tesc, Mmus\Cib4, Mmus\Tescl, Mmus\Chp1, Mmus\1700109H08Rik, Mmus\Cib1, Mmus\Chp2, Mmus\Ppp3r1, Mmus\Efcab1, Mmus\Ppp3r2" "Hsap\CHP1, Hsap\CIB4, Hsap\PPP3R2, Hsap\PPP3R1, Hsap\TESC, Hsap\CHP2, Hsap\EFCAB1, Hsap\CIB1" "viable,planar polarity defective" FBgn0261530 nbs nbs http://flybase.org/reports/FBgn0261530 protein_coding_gene ATP-dependent DNA helicase activity ; GO:0004003 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000255549 damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000255549 signal transduction in response to DNA damage ; GO:0042770 | inferred from mutant phenotype DNA duplex unwinding ; GO:0032508 | inferred from biological aspect of ancestor with PANTHER:PTN000255549 response to caffeine ; GO:0031000 | inferred from genetic interaction with MAGE cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred from mutant phenotype double-strand break repair via synthesis-dependent strand annealing ; GO:0045003 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred from direct assay telomere maintenance ; GO:0000723 | inferred from mutant phenotype intrinsic apoptotic signaling pathway in response to DNA damage ; GO:0008630 | inferred from mutant phenotype "nuclear chromosome, telomeric region ; GO:0000784 | inferred from biological aspect of ancestor with PANTHER:PTN000255549 Mre11 complex ; GO:0030870 | inferred from biological aspect of ancestor with PANTHER:PTN000255549" "nbs, Nbs, l(3)67BDr, l(3)67BDp, Nbs1, CG6754, l(3)e77A1, Dnbs1, NBS, 6754, NBS1" "IPR008984:SMAD/FHA domain, IPR001357:BRCT domain, IPR000253:Forkhead-associated (FHA) domain, IPR016592:Nibrin, IPR032429:Nibrin, second BRCT domain" CG6754 11-Aug-17 DroID_v2017_08 Drer\nbn - "Cele\ttn-1, Cele\H39E23.3" Xtro\nbn Mmus\Nbn Hsap\NBN DRSC11373 I 1.611432821 0.603789322 0.104101314 0.690760738 0.953776949 0.086898714 FBgn0260081 2L1506 - http://flybase.org/reports/FBgn0260081 gene - - - 2L1506 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0005342 Ring-magnified Ring magnified http://flybase.org/reports/FBgn0005342 - gene - - - "Rm, Ring-magnified" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058251 CG40251 - http://flybase.org/reports/FBgn0058251 protein_coding_gene - - - CG40251 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20820 I 0.41092869 -2.024144012 0.224217532 -0.008181882 FBgn0031418 CG3609 - http://flybase.org/reports/FBgn0031418 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR000683, InterPro:IPR004104" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR004104 - "CT12127, CG3609" "IPR000683:Oxidoreductase, N-terminal, IPR004104:Oxidoreductase, C-terminal, IPR016040:NAD(P)-binding domain" CG3609 11-Aug-17 DroID_v2017_08 "Drer\zgc:101723, Drer\zgc:154075, Drer\si:ch211-276f18.2, Drer\dhdhl" "Scer\YMR315W, Scer\GAL80" Cele\F53C11.1 "Xtro\dhdh, Xtro\gfod1" "Mmus\Gfod1, Mmus\Dhdh" "Hsap\DHDH, Hsap\GFOD1" "viable,fertile" FBgn0013448 fs(2)ry12 fs(2)ry12 http://flybase.org/reports/FBgn0013448 - gene - - - "fs(2)12, fs(2)ry12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0066100 MCP-2.s MCP-2.s http://flybase.org/reports/FBgn0066100 gene - - - MCP-2.s - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036995 atk artichoke http://flybase.org/reports/FBgn0036995 protein_coding_gene - sensory organ development ; GO:0007423 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from mutant phenotype extracellular matrix ; GO:0031012 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "tartan/capricious-like, CT16609, CG5195, atk" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG5195 11-Aug-17 DroID_v2017_08 "Drer\LOC101882074, Drer\LOC100330212, Drer\chadlb, Drer\lrit3a, Drer\si:dkey-182i3.11, Drer\lrit1a, Drer\lrit1b, Drer\lrrc53, Drer\chad, Drer\si:dkey-52j6.3, Drer\chadla, Drer\lrit3b" "Scer\CYR1, Scer\MMT2" "Cele\lron-9, Cele\lron-1, Cele\pan-1, Cele\lron-2, Cele\tol-1" "Xtro\chadl, Xtro\LOC100488097" "Mmus\Lgr5, Mmus\Cpn2, Mmus\Lrg1, Mmus\Tril, Mmus\Chad, Mmus\Lrrc26, Mmus\Chadl, Mmus\Lgr6, Mmus\Lrrc52, Mmus\Tlr3, Mmus\Lrit3, Mmus\Lrit1" "Hsap\LRG1, Hsap\LGR6, Hsap\CPN2, Hsap\TRIL, Hsap\CHAD, Hsap\CHADL, Hsap\LRRC52, Hsap\LGR5, Hsap\LRIT1, Hsap\LRIT3, Hsap\LRRC26" "viable,fertile,locomotor behavior defective,visible" "abdominal lateral pentascolopidial chordotonal organ lch5,mesothoracic tergum" DRSC11418 K -0.126537784 -0.139932838 -0.036318459 0.186485405 -0.337582267 1.578759288 FBgn0039879 Ir100a Ionotropic receptor 100a http://flybase.org/reports/FBgn0039879 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a sensory perception of taste ; GO:0050909 | inferred from expression pattern integral component of membrane ; GO:0016021 | inferred from sequence model "Ir100a, IR100a, CG11575, DmelIR100a" - CG11575 11-Aug-17 DroID_v2017_08 - - Cele\glr-8 - - - viable FBgn0033101 CG9436 - http://flybase.org/reports/FBgn0033101 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" - CG9436 "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG9436 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-180p18.9, Drer\akr1b1, Drer\akr1a1b, Drer\zgc:56622, Drer\zgc:110782, Drer\zgc:110366, Drer\zgc:101765, Drer\akr1a1a" "Scer\YPR1, Scer\GRE3, Scer\GCY1, Scer\ARA1, Scer\YDL124W, Scer\YJR096W" "Cele\ZC443.1, Cele\C35D10.6, Cele\ZK1290.5, Cele\C07D8.6, Cele\Y39G8B.1, Cele\Y39G8B.2, Cele\F53F1.2, Cele\F53F1.3, Cele\K07C5.2, Cele\T08H10.1, Cele\C56G3.2, Cele\C01G5.5" "Xtro\akr1a1, Xtro\akr1d1, Xtro\akr1c1, Xtro\akr1b1, Xtro\akr1c2, Xtro\LOC548351, Xtro\akr1c8p" "Mmus\Akr1c19, Mmus\Akr1c6, Mmus\Akr1b7, Mmus\Akr1c12, Mmus\Akr1a1, Mmus\Akr1b3, Mmus\Akr1c20, Mmus\Akr1b10, Mmus\Akr1c13, Mmus\Akr1c21, Mmus\Akr1e1, Mmus\Akr1c14, Mmus\Akr1cl, Mmus\Akr1c18, Mmus\Akr1d1, Mmus\Akr1b8" "Hsap\AKR1D1, Hsap\AKR1C4, Hsap\AKR1C2, Hsap\AKR1E2, Hsap\AKR1C3, Hsap\AKR1B10, Hsap\AKR1C1, Hsap\AKR1B1, Hsap\AKR1A1, Hsap\AKR1B15" viable FBgn0086406 BG01084 - http://flybase.org/reports/FBgn0086406 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01084 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0038087 beat-Va beat-Va http://flybase.org/reports/FBgn0038087 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic - "beat Va, CG10134, beat-Va, Beat-Va" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG10134 11-Aug-17 DroID_v2017_08 "Drer\f11r.2, Drer\jam2b" - - "Xtro\clmp, Xtro\esam" - "Hsap\CADM2, Hsap\F11R" viable FBgn0015504 l(3)95Aa lethal (3) 95Aa http://flybase.org/reports/FBgn0015504 - gene - - - "TnM2, l(3)95Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002333 l(3)87Ba lethal (3) 87Ba http://flybase.org/reports/FBgn0002333 - gene - - - "ck13, l(3)ck13, l(3)87Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" FBgn0259436 C618 - http://flybase.org/reports/FBgn0259436 gene - - - C618 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta" FBgn0266828 CR45290 - http://flybase.org/reports/FBgn0266828 non_protein_coding_gene - - - CR45290 - CR45290 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003316 saw sawtooth http://flybase.org/reports/FBgn0003316 - gene - - - saw - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,reduced" "wing margin bristle,wing" FBgn0005321 ni2 nicked on chromosome 2 http://flybase.org/reports/FBgn0005321 - gene - - - "ni, ni2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,recessive" wing FBgn0263095 CR43363 - http://flybase.org/reports/FBgn0263095 non_protein_coding_gene - - - "CR43363, lincRNA.201" - CR43363 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029997 CG2258 - http://flybase.org/reports/FBgn0029997 protein_coding_gene myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A - - CG2258 "IPR001452:SH3 domain, IPR018556:Domain of unknown function DUF2013" CG2258 11-Aug-17 DroID_v2017_08 Drer\nckipsd "Scer\BUD14, Scer\LDB17" Cele\Y55F3AM.5 Xtro\nckipsd Mmus\Nckipsd Hsap\NCKIPSD "viable,fertile,body color defective" mesothoracic tergum DRSC28795 K 0.452369194 -0.644786765 -0.441374216 0.893063952 -0.244659142 1.519945406 FBgn0024685 l(1)DC711 lethal (1) DC711 http://flybase.org/reports/FBgn0024685 - gene - - - l(1)DC711 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011390 l(3)j6A6 lethal (3) j6A6 http://flybase.org/reports/FBgn0011390 - gene - - - l(3)j6A6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013601 l(3)B7-3-32 lethal (3) B7-3-32 http://flybase.org/reports/FBgn0013601 - gene - - - l(3)B7-3-32 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262523 l(3)psg6 lethal (3) persistent salivary gland 6 http://flybase.org/reports/FBgn0262523 gene - regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype - "l(3)psg6, psg6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during P-stage" embryonic/larval salivary gland FBgn0058420 CG40420 - http://flybase.org/reports/FBgn0058420 protein_coding_gene - - - CG40420 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060820 l(3)S052319 lethal (3) S052319 http://flybase.org/reports/FBgn0060820 gene - - - "0523/19, l(3)S052319" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0001489 l(1)10Ai lethal (1) 10Ai http://flybase.org/reports/FBgn0001489 - gene - - - l(1)10Ai - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0265945 CR44732 - http://flybase.org/reports/FBgn0265945 non_protein_coding_gene - - - "CR44732, lincRNA.132" - CR44732 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263872 CR43719 - http://flybase.org/reports/FBgn0263872 non_protein_coding_gene - - - CR43719 - CR43719 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026648 l(2)65C2 lethal (2) 65C2 http://flybase.org/reports/FBgn0026648 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)65C2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0264904 CR44095 - http://flybase.org/reports/FBgn0264904 non_protein_coding_gene - - - CR44095 - CR44095 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261961 T:PH-step PH domain of step http://flybase.org/reports/FBgn0261961 engineered_tag - - - "T:PH-step, T:step" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002253 l(3)68Ee lethal (3) 68Ee http://flybase.org/reports/FBgn0002253 - gene - - - "rsg15, l(3)rsg15, l(3)68Ee" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060385 l(3)S134311b lethal (3) S134311b http://flybase.org/reports/FBgn0060385 gene - - - "1343/11, l(3)S134311b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0001495 l(1)10Bi lethal (1) 10Bi http://flybase.org/reports/FBgn0001495 - gene - - - "10Bi, l(1)G22, l(1)10Bi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0061099 l(3)S009512 lethal (3) S009512 http://flybase.org/reports/FBgn0061099 gene - - - "0095/12, l(3)S009512" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0260052 2L3456 - http://flybase.org/reports/FBgn0260052 gene - - - 2L3456 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0037194 CG12353 - http://flybase.org/reports/FBgn0037194 protein_coding_gene - - - CG12353 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027634 ms(1)268 ms(1)268 http://flybase.org/reports/FBgn0027634 - gene - - - ms(1)268 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0035469 CG14977 - http://flybase.org/reports/FBgn0035469 protein_coding_gene guanyl-nucleotide exchange factor activity ; GO:0005085 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q0VGL1 protein complex scaffold ; GO:0032947 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q0VGL1 positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype protein localization to lysosome ; GO:0061462 | inferred from sequence or structural similarity with UniProtKB:Q0VGL1 regulation of cell size ; GO:0008361 | inferred from sequence or structural similarity with UniProtKB:Q0VGL1 cellular response to amino acid stimulus ; GO:0071230 | inferred from mutant phenotype lysosome ; GO:0005764 | inferred from sequence or structural similarity with UniProtKB:Q0VGL1 Ragulator complex ; GO:0071986 | inferred from sequence or structural similarity with UniProtKB:Q0VGL1 "BcDNA:RH34338, CG14977, dC7orf59" IPR034601:Ragulator complex protein LAMTOR4 CG14977 11-Aug-17 DroID_v2017_08 Drer\si:dkey-159a18.7 - - Xtro\lamtor4 Mmus\Lamtor4 Hsap\LAMTOR4 viable FBgn0264911 CG44102 - http://flybase.org/reports/FBgn0264911 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44102 - CG44102 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039374 CG17770 - http://flybase.org/reports/FBgn0039374 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "CG17770, gene2, MLC2" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG17770 11-Aug-17 DroID_v2017_08 "Drer\calm1a, Drer\calm2b, Drer\cabp4, Drer\cabp2a, Drer\calml4b, Drer\rhbdl3, Drer\cabp5a, Drer\cabp5b, Drer\pvalb2, Drer\efcab6, Drer\tnnc1b, Drer\si:ch211-197n1.2, Drer\pvalb9, Drer\calm3a, Drer\calm2a, Drer\calb2b, Drer\cabp1b, Drer\efcab11, Drer\cabp1a, Drer\cabp2b, Drer\pvalb6, Drer\calb2a, Drer\calm3b, Drer\pvalb8, Drer\caln1, Drer\pvalb1, Drer\pvalb4, Drer\caln2, Drer\pvalb3, Drer\scgn, Drer\cabp7b, Drer\tnnc1a, Drer\calb1, Drer\calml4a, Drer\tnnc2, Drer\efcab2, Drer\calm1b" "Scer\CMD1, Scer\MLC1, Scer\MLC2" "Cele\cal-4, Cele\cal-2, Cele\cal-3, Cele\cmd-1, Cele\cal-1" "Xtro\LOC548651, Xtro\pvalb.2, Xtro\calm2, Xtro\pvalb.1, Xtro\cabp7, Xtro\scgn, Xtro\pgm1, Xtro\calb1, Xtro\calml4, Xtro\cabp4, Xtro\tnnc1, Xtro\ocm, Xtro\ocm.2, Xtro\pvalb, Xtro\efcab6, Xtro\calm1, Xtro\tnnc2" "Mmus\Efcab9, Mmus\Cabp5, Mmus\Calm3, Mmus\Cabp2, Mmus\Rhbdl3, Mmus\Calml4, Mmus\Calm1, Mmus\1700023F06Rik, Mmus\Calb2, Mmus\Scgn, Mmus\Efcab7, Mmus\Ocm, Mmus\Efcab3, Mmus\Cabp1, Mmus\Pvalb, Mmus\Efcab11, Mmus\Spata21, Mmus\Efcab2, Mmus\Calm2, Mmus\Calm4, Mmus\Calm5, Mmus\Tnnc2, Mmus\Tnnc1, Mmus\Efcab6, Mmus\Calb1, Mmus\Calml3, Mmus\Cabp4, Mmus\Caln1, Mmus\Cabp7" "Hsap\CALML3, Hsap\EFCAB7, Hsap\CALM3, Hsap\CALN1, Hsap\OCM2, Hsap\SCGN, Hsap\OCM, Hsap\CABP1, Hsap\EFCAB9, Hsap\TNNC1, Hsap\CALML5, Hsap\CABP2, Hsap\EFCAB11, Hsap\CALB1, Hsap\EFCAB3, Hsap\CALM2, Hsap\CALM1, Hsap\RHBDL3, Hsap\CALML6, Hsap\PVALB, Hsap\CABP5, Hsap\CABP4, Hsap\CABP7, Hsap\EFCAB2, Hsap\EFCAB6, Hsap\CALML4, Hsap\CALB2, Hsap\TNNC2, Hsap\EFCAB13, Hsap\SPATA21" viable FBgn0030724 Nipsnap Nipsnap http://flybase.org/reports/FBgn0030724 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000470715 "CG9212, Nipsnap" "IPR012577:NIPSNAP, IPR011008:Dimeric alpha-beta barrel" CG9212 11-Aug-17 DroID_v2017_08 "Drer\pgp, Drer\nipsnap3a, Drer\pdxp, Drer\gbas, Drer\nipsnap1" Scer\PHO13 "Cele\F44E7.2, Cele\K09H11.7, Cele\C45E5.1, Cele\K02D10.1" "Xtro\gbas, Xtro\nipsnap3a, Xtro\nipsnap1" "Mmus\Nipsnap3a, Mmus\Gbas, Mmus\Nipsnap3b, Mmus\Nipsnap1, Mmus\Pgp, Mmus\Pdxp" "Hsap\PDXP, Hsap\GBAS, Hsap\NIPSNAP3B, Hsap\NIPSNAP1, Hsap\PGP, Hsap\NIPSNAP3A" viable FBgn0015442 l(1)7Ci lethal (1) 7Ci http://flybase.org/reports/FBgn0015442 - gene - - - l(1)7Ci - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000537 eay early http://flybase.org/reports/FBgn0000537 - gene - - - eay - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,lethal,maternal effect" FBgn0025142 ms(3)A5 ms(3)A5 http://flybase.org/reports/FBgn0025142 - gene - - - ms(3)A5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0265099 CR44204 - http://flybase.org/reports/FBgn0265099 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44204, CR44204" - CR44204 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002881 mus105 mutagen-sensitive 105 http://flybase.org/reports/FBgn0002881 - gene - - - "l(1)d deg-1, mus-105, mus(1)105, l(1)dd1, l(1)d.deg-1, mus105" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,recessive,lethal,cell lethal,germline clone,chemical sensitive,radiation sensitive,female sterile,lethal - all die before end of larval stage,some die during larval stage" "mitosis & nuclear chromosome,imaginal disc,cell cycle" FBgn0035032 ATPsynF "ATP synthase, subunit F" http://flybase.org/reports/FBgn0035032 protein_coding_gene ATPase activity ; GO:0016887 | contributes_to inferred from sequence or structural similarity with HGNC:848 lateral inhibition ; GO:0046331 | inferred from mutant phenotype proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P56134 "lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with UniProtKB:P56134" "anon-EST:Posey45, CG4692, ATPK, ATPsynF" "IPR019344:Mitochondrial F1-F0 ATP synthase subunit F, predicted" CG4692 11-Aug-17 DroID_v2017_08 "Drer\atp5j2, Drer\si:dkey-21c1.4" - Cele\R53.4 Xtro\atp5j2 Mmus\Atp5j2 "Hsap\PTCD1, Hsap\ATP5J2" "viable,visible" "chaeta,trichogen cell" FBgn0061172 fra::unc-5 fra::unc-5 http://flybase.org/reports/FBgn0061172 engineered_fusion_gene - - - fra::unc-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "anterior commissure,posterior commissure,intersegmental nerve" FBgn0262480 CG43070 - http://flybase.org/reports/FBgn0262480 protein_coding_gene - - - "CG43070, lincRNA.347" - CG43070 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266838 CR45300 - http://flybase.org/reports/FBgn0266838 non_protein_coding_gene - - - CR45300 - CR45300 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028965 A16 A16 http://flybase.org/reports/FBgn0028965 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B biological_process ; GO:0008150 | no biological data available protein phosphatase type 1 complex ; GO:0000164 | colocalizes_with inferred from direct assay "CG9933, A16" IPR000953:Chromo/chromo shadow domain CG9933 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC03276 K -0.349950004 -0.699962587 0.450254212 -0.549468308 1.518266661 0.696612139 FBgn0028194 l(3)S022378 lethal (3) S022378 http://flybase.org/reports/FBgn0028194 gene - - - "0223/78, l(3)S022378" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032833 COX4 Cytochrome c oxidase subunit 4 http://flybase.org/reports/FBgn0032833 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000076140 cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P13073 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000076140 Golgi organization ; GO:0007030 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProtKB:P13073" lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000076140 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P13073 "IV, CG10664, COX IV, cox4, COXIV, COX, CoxIV, dCOX-IV, CcO IV, CX41, CX42, COX4, CoIV, C-IV s.4, Cox4" "IPR004203:Cytochrome c oxidase subunit IV family, IPR013288:Cytochrome c oxidase subunit IV" CG10664 11-Aug-17 DroID_v2017_08 "Drer\cox4i1l, Drer\cox4i2, Drer\cox4i1" "Scer\MTC3, Scer\COX5A, Scer\COX5B" Cele\W09C5.8 "Xtro\cox4i1, Xtro\cox4i2, Xtro\LOC100127750" "Mmus\Cox4i1, Mmus\Cox4i2" "Hsap\COX4I1, Hsap\COX4I2" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC23915 EK -1.212097348 -0.160552146 -1.865078656 -0.066512014 1.674157714 0.717441295 FBgn0042158 CG18835 - http://flybase.org/reports/FBgn0042158 protein_coding_gene - - - CG18835 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086372 lap like-AP180 http://flybase.org/reports/FBgn0086372 protein_coding_gene clathrin binding ; GO:0030276 | non-traceable author statement 1-phosphatidylinositol binding ; GO:0005545 | inferred from sequence or structural similarity with UniProtKB:O55012 clathrin binding ; GO:0030276 | inferred from sequence or structural similarity with UniProtKB:Q13492 clathrin coat assembly ; GO:0048268 | inferred from electronic annotation with InterPro:IPR014712 synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype inferred from physical interaction with Csp inferred from physical interaction with Syt1 inferred from physical interaction with nSyb inferred from physical interaction with VGlut positive regulation of clathrin-dependent endocytosis ; GO:2000370 | inferred from mutant phenotype receptor-mediated endocytosis ; GO:0006898 | inferred from direct assay neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype synaptic vesicle transport ; GO:0048489 | traceable author statement synaptic vesicle coating ; GO:0016183 | traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement phototaxis ; GO:0042331 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype clathrin-coated vesicle ; GO:0030136 | inferred from electronic annotation with InterPro:IPR014712 synaptic vesicle ; GO:0008021 | traceable author statement clathrin-coated pit ; GO:0005905 | inferred from direct assay "lap, l(3)neo34, CG2520, AP180, lap/AP180, Lap, LAP, sig, dAP-3, BcDNA:GM10787, EP(3)3060, EP3060" "IPR011417:AP180 N-terminal homology (ANTH) domain, IPR008942:ENTH/VHS, IPR013809:ENTH domain, IPR014712:Phosphoinositide-binding clathrin adaptor, domain 2, IPR015943:WD40/YVTN repeat-like-containing domain" CG2520 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-214j24.9, Drer\LOC100005187, Drer\snap91, Drer\si:ch211-200p22.4, Drer\picalma, Drer\picalmb" "Scer\YAP1802, Scer\YAP1801" Cele\unc-11 "Xtro\picalm.2, Xtro\snap91" "Mmus\Picalm, Mmus\Snap91" "Hsap\SNAP91, Hsap\PICALM" embryonic stage " embryonic central nervous system

, embryonic peripheral nervous system

, garland cell

" larval stage " neuromuscular junction

, bouton

" FBgn0266004 CR44778 - http://flybase.org/reports/FBgn0266004 non_protein_coding_gene - - - CR44778 - CR44778 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023527 CG3071 - http://flybase.org/reports/FBgn0023527 - protein_coding_gene snoRNA binding ; GO:0030515 | inferred from sequence or structural similarity with SGD:S000004699 "cellular response to starvation ; GO:0009267 | inferred from expression pattern positive regulation of transcription from RNA polymerase I promoter ; GO:0045943 | inferred from sequence or structural similarity with SGD:S000004699 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from sequence or structural similarity with SGD:S000004699" t-UTP complex ; GO:0034455 | inferred from sequence or structural similarity with SGD:S000004699 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with SGD:S000004699 "CG3071, EG:25E8.3" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR018983:U3 small nucleolar RNA-associated protein 15, C-terminal" CG3071 11-Aug-17 DroID_v2017_08 Drer\utp15 Scer\UTP15 Cele\Y23H5B.5 Xtro\utp15 Mmus\Utp15 "Hsap\TLE3, Hsap\UTP15, Hsap\WDR89" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0052814 CG32814 - http://flybase.org/reports/FBgn0052814 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32814 - CG32814 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002326 l(3)86Fe lethal (3) 86Fe http://flybase.org/reports/FBgn0002326 - gene - - - "ck5, l(3)ck5, l(3)86Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0267181 CR45621 - http://flybase.org/reports/FBgn0267181 non_protein_coding_gene - - - CR45621 - CR45621 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267079 CR45523 - http://flybase.org/reports/FBgn0267079 non_protein_coding_gene - - - CR45523 - CR45523 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029024 l(3)77ABh lethal (3) 77ABh http://flybase.org/reports/FBgn0029024 gene - - - l(3)77ABh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004401 Pep Protein on ecdysone puffs http://flybase.org/reports/FBgn0004401 FBgn0036743 protein_coding_gene single-stranded RNA binding ; GO:0003727 | inferred from direct assay single-stranded DNA binding ; GO:0003697 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay "regulation of mRNA splicing, via spliceosome ; GO:0048024 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay polytene chromosome puff ; GO:0005703 | colocalizes_with inferred from direct assay "CG6143, PEP/X4, p100, X4/PEP, PEP, Pep, pep" IPR013087:Zinc finger C2H2-type CG6143 11-Aug-17 DroID_v2017_08 "Drer\pnn, Drer\ciz1a, Drer\ciz1b" - - - Mmus\Ciz1 Hsap\CIZ1 embryonic stage -- adult stage viable FBgn0069420 JJF095 JJF095 http://flybase.org/reports/FBgn0069420 gene - - - JJF095 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0263406 CR43452 - http://flybase.org/reports/FBgn0263406 non_protein_coding_gene - - - CR43452 - CR43452 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010732 l(3)00864 lethal (3) 00864 http://flybase.org/reports/FBgn0010732 FBgn0011494 gene - - - "l(3)rG084, l(3)00864" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038294 Mf Myofilin http://flybase.org/reports/FBgn0038294 protein_coding_gene - wing disc development ; GO:0035220 | inferred from genetic interaction with Bx inferred from genetic interaction with ap chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp inferred from genetic interaction with Chi A band ; GO:0031672 | inferred from direct assay "CG6803, z1, BcDNA:GH23305, Mf, DmMf, Zeelin1" IPR031828:Myofilin CG6803 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260965 CG42588 - http://flybase.org/reports/FBgn0260965 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG34017, CG42588, CG11008, BP1016, BcDNA:SD20456, CG32108" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG42588 11-Aug-17 DroID_v2017_08 Drer\gtf3c2 Scer\TFC6 - Xtro\gtf3c2 Mmus\Gtf3c2 Hsap\GTF3C2 FBgn0038697 CG3581 - http://flybase.org/reports/FBgn0038697 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG3581 IPR006623:Testicular haploid expressed repeat CG3581 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065850 l(2)SH0307 lethal (2) SH0307 http://flybase.org/reports/FBgn0065850 gene - - - "l(2)SH0307, l(2)SH2 0307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001580 l(1)AL2 lethal (1) AL2 http://flybase.org/reports/FBgn0001580 - gene - - - l(1)AL2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,short lived" FBgn0038389 CG5516 - http://flybase.org/reports/FBgn0038389 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG5516 "IPR001878:Zinc finger, CCHC-type" CG5516 11-Aug-17 DroID_v2017_08 Drer\zcchc10 Scer\BSC1 - Xtro\zcchc10 Mmus\Zcchc10 Hsap\ZCCHC10 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0005209 l(3)LVML lethal (3) LVML http://flybase.org/reports/FBgn0005209 - gene - - - l(3)LVML - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011148 l(1)Q224 lethal (1) Q224 http://flybase.org/reports/FBgn0011148 FBgn0010210 gene - - - l(1)Q224 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259791 bora aurora borealis http://flybase.org/reports/FBgn0259791 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VGF9 activation of protein kinase activity ; GO:0032147 | inferred from direct assay asymmetric protein localization involved in cell fate determination ; GO:0045167 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "bora, CG6897" IPR023252:Aurora borealis protein CG6897 11-Aug-17 DroID_v2017_08 Drer\bora - Cele\spat-1 - Mmus\Bora Hsap\BORA FBgn0040527 CG11603 - http://flybase.org/reports/FBgn0040527 protein_coding_gene - - - CG11603 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065654 l(2)SH0727 lethal (2) SH0727 http://flybase.org/reports/FBgn0065654 gene - - - "l(2)SH0727, l(2)SH2 0727" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060420 l(3)S128306 lethal (3) S128306 http://flybase.org/reports/FBgn0060420 gene - - - "1283/06, l(3)S128306" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266035 CR44800 - http://flybase.org/reports/FBgn0266035 non_protein_coding_gene - - - "CR44800, lincRNA.71" - CR44800 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067868 Mod(Prat:bw)3-7 Mod(Prat:bw)3-7 http://flybase.org/reports/FBgn0067868 gene - - - "Mod-3-7, Mod(Prat:bw)3-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265081 CR44192 - http://flybase.org/reports/FBgn0265081 non_protein_coding_gene - - - CR44192 - CR44192 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259661 B0295 - http://flybase.org/reports/FBgn0259661 gene - - - B0295 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038606 CG15803 - http://flybase.org/reports/FBgn0038606 protein_coding_gene protein C-terminus binding ; GO:0008022 | inferred from sequence or structural similarity with HGNC:7208 biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:7208 "CG15803, lincRNA.804" IPR001478:PDZ domain CG15803 11-Aug-17 DroID_v2017_08 "Drer\il16, Drer\LOC564220, Drer\grip2b, Drer\pard3bb, Drer\grip1, Drer\slc9a3r1, Drer\lnx1, Drer\inadl, Drer\dlg5a, Drer\grid2ipa, Drer\pdzd7b, Drer\si:dkey-92i15.4" - Cele\mpz-1 "Xtro\grip1, Xtro\lnx1, Xtro\dlg5, Xtro\grip2, Xtro\grid2ip" "Mmus\Mpdz, Mmus\Ush1c, Mmus\Patj, Mmus\Grasp, Mmus\Pdzph1, Mmus\Pdzd11, Mmus\Grip1, Mmus\Grip2, Mmus\Pdzd2, Mmus\Grid2ip, Mmus\Lnx1, Mmus\Dlg5, Mmus\Il16" "Hsap\GRIP1, Hsap\PARD3B, Hsap\MPDZ, Hsap\GRASP, Hsap\LNX1, Hsap\FRMPD2, Hsap\GRID2IP, Hsap\USH1C, Hsap\PATJ, Hsap\DLG5, Hsap\IL16, Hsap\PDZD2" viable FBgn0260816 EY13010 - http://flybase.org/reports/FBgn0260816 gene - - - EY13010 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0067636 146y 146y http://flybase.org/reports/FBgn0067636 gene - - - 146y - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0024540 l(3)L2049 lethal (3) L2049 http://flybase.org/reports/FBgn0024540 - gene - - - l(3)L2049 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065390 l(2)SH1630 lethal (2) SH1630 http://flybase.org/reports/FBgn0065390 gene - - - "l(2)SH1630, l(2)SH2 1630" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052437 CG32437 - http://flybase.org/reports/FBgn0052437 protein_coding_gene - - - "CG5051, CG32437" IPR031732:Protein of unknown function DUF4729 CG32437 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036762 CG7430 - http://flybase.org/reports/FBgn0036762 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR006258, InterPro:IPR016156 dihydrolipoyl dehydrogenase activity ; GO:0004148 | inferred from sequence or structural similarity with UniProtKB:P09622" cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR004099 glycine catabolic process ; GO:0006546 | inferred from sequence or structural similarity with UniProtKB:P09622 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P09622 lipoamide metabolic process ; GO:0006748 | inferred from sequence or structural similarity with UniProtKB:P09622 mitochondrial alpha-ketoglutarate dehydrogenase complex ; GO:0005947 | inferred from sequence or structural similarity with UniProtKB:P09622 lipid particle ; GO:0005811 | inferred from direct assay glycine cleavage complex ; GO:0005960 | inferred from sequence or structural similarity with UniProtKB:P09622 "CG7430, E3" "IPR004099:Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, IPR006258:Dihydrolipoamide dehydrogenase, IPR012999:Pyridine nucleotide-disulphide oxidoreductase, class I, active site, IPR023753:FAD/NAD(P)-binding domain, IPR016156:FAD/NAD-linked reductase, dimerisation domain" CG7430 11-Aug-17 DroID_v2017_08 Drer\dldh "Scer\IRC15, Scer\LPD1" Cele\dld-1 Xtro\dld Mmus\Dld Hsap\DLD viable FBgn0085383 CG34354 - http://flybase.org/reports/FBgn0085383 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "CG34354, CG12425, CG12852, cg4787, CG4787" IPR000504:RNA recognition motif domain CG34354 11-Aug-17 DroID_v2017_08 "Drer\zcrb1, Drer\rbm34, Drer\hnrnpabb, Drer\eif4h, Drer\hnrnpa3, Drer\trnau1apa, Drer\hnrnpc, Drer\cirbpa, Drer\raly, Drer\wu:fq32h04, Drer\tial1, Drer\srsf10a, Drer\trnau1apb, Drer\tia1, Drer\tia1l, Drer\ncoa5, Drer\hnrnpaba, Drer\dazl, Drer\hnrnpa1b, Drer\zgc:55733, Drer\eif4ba, Drer\hnrnpd" "Scer\NOP6, Scer\NAB6, Scer\PUB1, Scer\NOP12, Scer\MRN1, Scer\NAM8, Scer\CWC2, Scer\MUD1, Scer\NGR1" "Cele\tiar-1, Cele\tiar-3, Cele\tiar-2" "Xtro\tia1, Xtro\hnrnpa1, Xtro\hnrnpdl, Xtro\rbm34, Xtro\hnrnpc, Xtro\eif4b, Xtro\ralyl, Xtro\eif4h, Xtro\cirbp, Xtro\raly, Xtro\trnau1ap, Xtro\hnrnpab, Xtro\dazl, Xtro\hnrnpd, Xtro\hnrnpa3, Xtro\hnrnpa2b1" "Mmus\Hnrnpa3, Mmus\Gm21379, Mmus\Raly, Mmus\Hnrnpab, Mmus\Zcrb1, Mmus\Dazl, Mmus\Trnau1ap, Mmus\Hnrnpc, Mmus\Eif4b, Mmus\Tial1, Mmus\Tia1, Mmus\Slirp, Mmus\Eif4h, Mmus\Rbm31y, Mmus\Hnrnpa1, Mmus\Rbm34, Mmus\Hnrnpa2b1, Mmus\Srsf12, Mmus\Tra2b, Mmus\Boll, Mmus\Hnrnpd, Mmus\Cirbp, Mmus\Srsf10" "Hsap\DAZ2, Hsap\TIAL1, Hsap\DAZL, Hsap\SLIRP, Hsap\TRNAU1AP, Hsap\RALY, Hsap\RBM3, Hsap\HNRNPAB, Hsap\RBM34, Hsap\HNRNPA1, Hsap\HNRNPC, Hsap\DAZ4, Hsap\CIRBP, Hsap\DAZ3, Hsap\BOLL, Hsap\HNRNPCL1, Hsap\HNRNPA2B1, Hsap\HNRNPA1L2, Hsap\TIA1, Hsap\HNRNPD, Hsap\EIF4B, Hsap\EIF4H, Hsap\SRSF10, Hsap\DAZ1, Hsap\RALYL, Hsap\HNRNPA3" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032025 CG7778 - http://flybase.org/reports/FBgn0032025 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG7778 - CG7778 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0033322 CG8584 - http://flybase.org/reports/FBgn0033322 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from biological aspect of ancestor with PANTHER:PTN000258719 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with HGNC:19085 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:19085 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:19085 "BEST:LP01468, CG8584, 19527701" "IPR004274:FCP1 homology domain, IPR011948:Dullard phosphatase domain, eukaryotic, IPR023214:HAD-like domain" CG8584 11-Aug-17 DroID_v2017_08 "Drer\ctdsp2, Drer\ctdnep1b, Drer\ctdspl2b, Drer\ublcp1, Drer\ctdsp1, Drer\ctdspl2a, Drer\ctdnep1a, Drer\ctdspl3, Drer\ctdspla, Drer\ctdsplb" "Scer\PSR2, Scer\NEM1, Scer\PSR1" "Cele\scpl-1, Cele\cnep-1" "Xtro\ctdnep1, Xtro\ctdsp2, Xtro\ctdsp1, Xtro\ctdspl2, Xtro\ctdspl, Xtro\ublcp1" "Mmus\Ctdsp1, Mmus\Ctdsp2, Mmus\Ctdspl, Mmus\Ctdnep1, Mmus\Ublcp1, Mmus\Ctdspl2" "Hsap\CTDSPL2, Hsap\CTDNEP1, Hsap\CTDSP2, Hsap\CTDSPL, Hsap\CTDSP1, Hsap\UBLCP1" viable FBgn0264599 CR43948 - http://flybase.org/reports/FBgn0264599 non_protein_coding_gene - - - CR43948 - CR43948 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262033 CR42844 - http://flybase.org/reports/FBgn0262033 non_protein_coding_gene - - - "CG42844, CR42844, lincRNA.85" - CR42844 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052652 CR32652 - http://flybase.org/reports/FBgn0052652 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs14f06, bs27g02.y1, bs27e03.y1, bs24h05.y1, bs16e05.y1, bs14d08.y1, bs02c02.y1, bs13e06.y1, bs30c01.y1, bs08g03.y1, bs14f06.y1, NEST:bs30c01, NEST:bs29d03, NEST:bs27g02, NEST:bs27e03, NEST:bs24h05, NEST:bs23h05, NEST:bs16e05, NEST:bs13e06, NEST:bs08g03, NEST:bs02c02, CG32652, CR32652, mdcds_53609" - CR32652 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259418 C343 - http://flybase.org/reports/FBgn0259418 gene - - - C343 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0028568 robl60C robl60C http://flybase.org/reports/FBgn0028568 gene - - - robl60C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051410 Npc2e Niemann-Pick type C-2e http://flybase.org/reports/FBgn0051410 protein_coding_gene sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 lipopolysaccharide binding ; GO:0001530 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from direct assay lipoteichoic acid binding ; GO:0070891 | inferred from direct assay lipid antigen binding ; GO:0030882 | inferred from direct assay sterol transport ; GO:0015918 | inferred from sequence or structural similarity with Npc2a peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "CG3928, npc2e, Npc2e, CG31410" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set" CG31410 11-Aug-17 DroID_v2017_08 "Drer\zgc:193725, Drer\npc2" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 viable FBgn0013983 imd immune deficiency http://flybase.org/reports/FBgn0013983 "FBgn0034344, FBgn0046434" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V3B4 protein binding ; GO:0005515 | inferred from physical interaction with pirk death domain binding ; GO:0070513 | inferred from physical interaction with Fadd protein binding ; GO:0005515 | inferred from physical interaction with Usp2 intracellular signal transduction ; GO:0035556 | traceable author statement antibacterial humoral response ; GO:0019731 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | traceable author statement positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype defense response ; GO:0006952 | traceable author statement peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype innate immune response ; GO:0045087 | non-traceable author statement nervous system development ; GO:0007399 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from genetic interaction with Tl humoral immune response ; GO:0006959 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from mutant phenotype response to bacterium ; GO:0009617 | non-traceable author statement antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype intracellular ; GO:0005622 | non-traceable author statement "imd, CG5576, IMD, Imd, BG5, shadok, anon-WO0172774.166" "IPR000488:Death domain, IPR011029:Death-like domain" CG5576 11-Aug-17 DroID_v2017_08 "Drer\zgc:174906, Drer\fadd" - - - "Mmus\Fadd, Mmus\Pidd1" "Hsap\FADD, Hsap\PIDD1" "short lived,immune response defective,viable,fertile,radiation resistant,recessive,increased cell death,radiation sensitive,lethal - all die before end of larval stage,some die during larval stage" embryonic/larval fat body FBgn0085481 CG34452 - http://flybase.org/reports/FBgn0085481 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 galactosyltransferase activity ; GO:0008378 | inferred from sequence or structural similarity with CG8708 "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 protein glycosylation ; GO:0006486 | inferred from sequence or structural similarity with CG8708" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 cellular_component ; GO:0005575 | no biological data available "CG34452, CG33999, BP1049" IPR003378:Fringe-like CG34452 11-Aug-17 DroID_v2017_08 "Drer\LOC564281, Drer\c1galt1c1, Drer\c1galt1b, Drer\si:dkey-202e17.1, Drer\c1galt1a" - "Cele\Y38C1AB.5, Cele\C17A2.3, Cele\E03H4.3, Cele\W09D10.5, Cele\bus-4, Cele\C02H6.1, Cele\C38H2.2, Cele\T09E11.12, Cele\F56H6.1, Cele\F37A4.3, Cele\C16D9.6, Cele\Y38C1AB.1" "Xtro\LOC100496837, Xtro\c1galt1, Xtro\c1galt1c1" "Mmus\C1galt1, Mmus\C1galt1c1" "Hsap\C1GALT1C1L, Hsap\C1GALT1C1, Hsap\C1GALT1" FBgn0004174 Mst84Dc Male-specific RNA 84Dc http://flybase.org/reports/FBgn0004174 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis ; GO:0007283 | inferred from genetic interaction with Mst84Da, Mst84Db, Mst84Dd sperm axoneme assembly ; GO:0007288 | inferred from genetic interaction with Mst84Da, Mst84Db, Mst84Dd" cellular_component ; GO:0005575 | no biological data available "Mst, Mstprox, Mst ORF, Mst84, Mst87D, mst(3)gl-3, CG17945, Mst84Dc, Mst84D" IPR005634:Male specific sperm protein CG17945 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060998 l(3)S027022 lethal (3) S027022 http://flybase.org/reports/FBgn0060998 gene - - - "0270/22, l(3)S027022" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040130 l(2)22Ai lethal (2) 22Ai http://flybase.org/reports/FBgn0040130 gene - - - "D, l(2)22Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040858 CG11359 - http://flybase.org/reports/FBgn0040858 protein_coding_gene - - - CG11359 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032268 CG6138 - http://flybase.org/reports/FBgn0032268 protein_coding_gene - - - "BcDNA:AT25107, CG6138" - CG6138 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0019925 Surf4 Surfeit 4 http://flybase.org/reports/FBgn0019925 - protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002995 fusome ; GO:0045169 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "Surf4, SURF-4, Surf-4, CG6202" IPR002995:Surfeit locus 4 CG6202 11-Aug-17 DroID_v2017_08 "Drer\surf4l, Drer\surf4" Scer\ERV29 "Cele\sft-4, Cele\T02E1.7" "Xtro\surf4.2, Xtro\surf4.1" Mmus\Surf4 Hsap\SURF4 "lethal,viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0005026 drp droop wings http://flybase.org/reports/FBgn0005026 - gene - - - drp - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0061010 l(3)S026220b lethal (3) S026220b http://flybase.org/reports/FBgn0061010 gene - - - "0262/20, l(3)S026220b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002489 l(3)SG49 lethal (3) SG49 http://flybase.org/reports/FBgn0002489 FBgn0004726 gene - - - "l(3)ds8, l(3)SG49" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0004216 l(3)84Fd lethal (3) 84Fd http://flybase.org/reports/FBgn0004216 - gene - - - l(3)84Fd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058085 CG40085 - http://flybase.org/reports/FBgn0058085 protein_coding_gene - - - CG40085 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013518 l(1)rp1 lethal (1) rp1 http://flybase.org/reports/FBgn0013518 - gene - - - l(1)rp1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0250737 l(3)S091911 lethal (3) S091911 http://flybase.org/reports/FBgn0250737 gene - - - "l(3)S091911, l(3)s091911" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267804 CR46129 - http://flybase.org/reports/FBgn0267804 non_protein_coding_gene - - - CR46129 - CR46129 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037742 Rpt3R Regulatory particle triple-A ATPase 3-related http://flybase.org/reports/FBgn0037742 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001270, InterPro:IPR003959, InterPro:IPR003960 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ATPase activity ; GO:0016887 | inferred from sequence model" cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with Rpt3 "nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000002802" "CG9475, Dm_Rpt3b, DmCG9475, Rpt3R, 9475, S6" "IPR001270:ClpA/B family, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9475 11-Aug-17 DroID_v2017_08 "Drer\psmc1a, Drer\psmc4" Scer\RPT3 "Cele\rpt-3, Cele\C10G11.8, Cele\rpt-2" "Xtro\psmc1, Xtro\psmc4" "Mmus\Psmc4, Mmus\Psmc1" "Hsap\PSMC1, Hsap\PSMC4" DRSC16501 IEK -0.672692436 -2.138248117 -2.280806853 -0.602518049 2.231512421 1.310186938 FBgn0035094 CG9380 - http://flybase.org/reports/FBgn0035094 protein_coding_gene - - - CG9380 IPR015510:Peptidoglycan recognition protein CG9380 11-Aug-17 DroID_v2017_08 "Drer\pglyrp6, Drer\pglyrp2" - - - "Mmus\Pglyrp2, Mmus\Pglyrp1" "Hsap\PGLYRP1, Hsap\PGLYRP2" viable FBgn0039598 aqrs aquarius http://flybase.org/reports/FBgn0039598 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype sperm storage ; GO:0046693 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay "CG14061, aqrs" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG14061 11-Aug-17 DroID_v2017_08 - - - Xtro\tpsg1 "Mmus\Prss34, Mmus\Klk7, Mmus\Prss48, Mmus\Prss29, Mmus\Prss27, Mmus\Klk8, Mmus\Klk12, Mmus\Prss28, Mmus\Klk14, Mmus\Klk10, Mmus\F12, Mmus\Tpsg1, Mmus\Tpsb2, Mmus\Prss21, Mmus\Prss30, Mmus\Prss33, Mmus\Prss46, Mmus\Prss32, Mmus\Klk4, Mmus\Hgfac, Mmus\Tpsab1, Mmus\Klk5" "Hsap\TPSD1, Hsap\KLK8, Hsap\PRSS33, Hsap\PRSS21, Hsap\TPSG1, Hsap\KLK7, Hsap\KLK10, Hsap\KLK5, Hsap\KLK14, Hsap\TPSAB1, Hsap\KLK4, Hsap\HGFAC, Hsap\PRSS48, Hsap\KLK12, Hsap\F12, Hsap\TPSB2" "mating behavior defective,female limited,female semi-fertile" seminal receptacle FBgn0031638 CG11927 - http://flybase.org/reports/FBgn0031638 protein_coding_gene - - - CG11927 - CG11927 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC00337 K 0.492620194 -0.700530618 0.158035351 -0.285140326 0.659951645 2.688319159 FBgn0265801 CR44590 - http://flybase.org/reports/FBgn0265801 non_protein_coding_gene - - - CR44590 - CR44590 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017631 Eig17B Eig17B http://flybase.org/reports/FBgn0017631 - gene - - - "Eig17-2, Eig17B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027992 l(3)S126705 lethal (3) S126705 http://flybase.org/reports/FBgn0027992 gene - - - "1267/05, 0428/25, l(3)S126705" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0023121 anon-10Am anon-10Am http://flybase.org/reports/FBgn0023121 - gene - - - "5, anon-10Am" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262414 mir-4 mir-4 stem loop http://flybase.org/reports/FBgn0262414 miRNA_gene - - - "miR-4, mir-4, 4, CR42961, CR33038, CR33561, mir-4*, mir-4S" - CR42961 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | first instar , embryonic stage " visible "chaeta,ectopic,wing disc" FBgn0036717 CG13731 - http://flybase.org/reports/FBgn0036717 protein_coding_gene - - - CG13731 - CG13731 11-Aug-17 DroID_v2017_08 - - Cele\F35A5.1 - - Hsap\FAM47C FBgn0263951 BG00890 - http://flybase.org/reports/FBgn0263951 gene - - - BG00890 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective" FBgn0261617 nej nejire http://flybase.org/reports/FBgn0261617 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000197, InterPro:IPR000433 histone acetyltransferase activity ; GO:0004402 | inferred from direct assay histone acetyltransferase activity (H3-K27 specific) ; GO:0044017 | inferred from direct assay cAMP response element binding protein binding ; GO:0008140 | traceable author statement transcription coactivator activity ; GO:0003713 | inferred from genetic interaction with ci transcription factor binding ; GO:0008134 | inferred from physical interaction with ci histone methyltransferase binding ; GO:1990226 | inferred from physical interaction with ash1 transcription coactivator activity ; GO:0003713 | inferred from direct assay inferred from genetic interaction with per histone acetyltransferase activity (H3-K18 specific) ; GO:0043993 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Clk histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with mod" neurogenesis ; GO:0022008 | inferred from mutant phenotype thermosensory behavior ; GO:0040040 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype inferred from genetic interaction with Myb histone H4-K8 acetylation ; GO:0043982 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype hemopoiesis ; GO:0030097 | traceable author statement smoothened signaling pathway ; GO:0007224 | non-traceable author statement histone H3-K27 acetylation ; GO:0043974 | inferred from direct assay synapse assembly ; GO:0007416 | inferred from mutant phenotype R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype histone H3-K18 acetylation ; GO:0043971 | inferred from direct assay Wnt signaling pathway ; GO:0016055 | non-traceable author statement histone acetylation ; GO:0016573 | inferred from direct assay DNA replication checkpoint ; GO:0000076 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype histone H4-K12 acetylation ; GO:0043983 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype circadian regulation of gene expression ; GO:0032922 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype inferred from genetic interaction with ci regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay histone methyltransferase complex ; GO:0035097 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with ash1 protein complex ; GO:0043234 | inferred from physical interaction with mod histone acetyltransferase complex ; GO:0000123 | inferred from direct assay "CBP, nej CBP, dCBP, dmCBP, CG15319, CBP/p300, nej, anon-WO0147981.11, p300/CBP, cbp, Cbp, CBP_, Crbp, anon-WO03040301.89, p300, Nej, CG15321, l(1)G0350, l(1)G0112, l(1)G0470, dKAT3, Nejire" "IPR018359:Bromodomain, conserved site, IPR000197:Zinc finger, TAZ-type, IPR000433:Zinc finger, ZZ-type, IPR001487:Bromodomain, IPR003101:Coactivator CBP, KIX domain, IPR010303:CREB-binding protein/p300, atypical RING domain, IPR009110:Nuclear receptor coactivator, interlocking, IPR019786:Zinc finger, PHD-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013178:Histone acetyltransferase Rtt109/CBP, IPR014744:Nuclear receptor coactivator, CREB-bp-like, interlocking, IPR031162:CBP/p300-type histone acetyltransferase domain" CG15319 11-Aug-17 DroID_v2017_08 "Drer\crebbpb, Drer\ep300b, Drer\ep300a, Drer\crebbpa" "Scer\BDF1, Scer\BDF2" "Cele\ZK1010.10, Cele\C29F9.5, Cele\C29F9.6, Cele\C49F5.5, Cele\F40F12.7, Cele\cbp-1, Cele\F22F1.3, Cele\cbp-2" Xtro\crebbp "Mmus\Crebbp, Mmus\Ep300" "Hsap\CREBBP, Hsap\EP300" embryonic stage | cellular blastoderm """DRSC18801, DRSC18006"" " IEK FBgn0003033 pal paternal loss inducer http://flybase.org/reports/FBgn0003033 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "mei-W5, pal" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,mitotic cell cycle defective,meiotic cell cycle defective,male,recessive" nuclear chromosome | male FBgn0060898 l(3)S044221a lethal (3) S044221a http://flybase.org/reports/FBgn0060898 gene - - - "0442/21, l(3)S044221a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0037876 CG4820 - http://flybase.org/reports/FBgn0037876 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG4820 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4820 11-Aug-17 DroID_v2017_08 Drer\znf408 Scer\AZF1 "Cele\che-1, Cele\M03D4.4" - Mmus\Zfp148 Hsap\ZNF8 viable FBgn0028514 CG4793 - http://flybase.org/reports/FBgn0028514 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 positive regulation of hemocyte proliferation ; GO:0035208 | inferred from genetic interaction with hop - "SPH208, BG:DS07486.3, CG4793" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG4793 11-Aug-17 DroID_v2017_08 Drer\f7 - - - "Mmus\Klk1b27, Mmus\Klk1b22, Mmus\Klk1b1, Mmus\Klk1b24, Mmus\Klkb1, Mmus\Klk1, Mmus\Klk1b11, Mmus\Klk1b5, Mmus\Klk1b9, Mmus\Klk1b21, Mmus\F11, Mmus\Klk1b26, Mmus\Klk11, Mmus\Klk1b8, Mmus\Klk1b3, Mmus\Klk1b4, Mmus\Egfbp2, Mmus\Klk1b16, Mmus\F9" "Hsap\KLKB1, Hsap\F9, Hsap\PLG, Hsap\F11, Hsap\KLK2, Hsap\KLK1, Hsap\F10, Hsap\KLK11, Hsap\KLK3, Hsap\PRSS21" viable FBgn0259578 B1513 - http://flybase.org/reports/FBgn0259578 gene - - - B1513 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,macrochaeta" FBgn0082367 EP3582 EP3582 http://flybase.org/reports/FBgn0082367 gene - - - EP3582 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0041747 l(1)em2 lethal (1) em2 http://flybase.org/reports/FBgn0041747 gene - - - l(1)em2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065881 l(2)SH0235 lethal (2) SH0235 http://flybase.org/reports/FBgn0065881 gene - - - "l(2)SH0235, l(2)SH2 0235" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013551 l(3)ry103 lethal (3) ry103 http://flybase.org/reports/FBgn0013551 "FBgn0013572, FBgn0014321" gene - - - "l(3)103, l(3)ry147, l(3)82AB, l(3)ry103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060367 l(3)S138111 lethal (3) S138111 http://flybase.org/reports/FBgn0060367 gene - - - "1381/11, l(3)S138111" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0024199 pinto pinto http://flybase.org/reports/FBgn0024199 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "pin, pinto" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004527 l(4)102CDj lethal (4) 102CDj http://flybase.org/reports/FBgn0004527 - gene - - - "l(4)CDj, l(4)ST-4, l(4)SLC-1, l(4)15, l(4)MW-1, l(4)102CDj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,visible" "male genitalia,wing,wing vein" FBgn0019905 anon-14Be anon-14Be http://flybase.org/reports/FBgn0019905 - gene - - - "ORF, anon-14Be" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260238 CG42512 - http://flybase.org/reports/FBgn0260238 protein_coding_gene - - - "CG42512, Dromel_CG32573_FBtr0074315_uORF, CG42528" - CG42512 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085612 CR41320 - http://flybase.org/reports/FBgn0085612 pseudogene_attribute - - - "CG41320, CR41320" - CR41320 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264253 Send2 Spermathecal endopeptidase 2 http://flybase.org/reports/FBgn0264253 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "Send2, CG18125, SPH190, DS01068.10, BG:DS01068.10" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG18125 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.9, Drer\si:dkey-78l4.5" - "Cele\try-1, Cele\svh-1" - "Mmus\Klk1b3, Mmus\Klk1b9, Mmus\Prss53, Mmus\Klk14, Mmus\Klk1b5, Mmus\Prss36, Mmus\Egfbp2" "Hsap\PRSS53, Hsap\PRSS36" FBgn0031345 CG18132 - http://flybase.org/reports/FBgn0031345 protein_coding_gene - cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 - CG18132 "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain" CG18132 11-Aug-17 DroID_v2017_08 "Drer\erp27, Drer\pdia6, Drer\txndc5, Drer\txndc16, Drer\dnajc10" "Scer\MPD1, Scer\EPS1, Scer\MPD2" - "Xtro\txndc5, Xtro\pdia6, Xtro\txndc16" "Mmus\Pdia5, Mmus\Txndc16, Mmus\Pdia6, Mmus\Txndc5, Mmus\Dnajc10, Mmus\Erp27" "Hsap\PDIA6, Hsap\DNAJC10, Hsap\TXNDC5, Hsap\TXNDC16, Hsap\PDIA5, Hsap\PDILT, Hsap\ERP27" viable DRSC00518 K 0.671478908 -0.878700261 0.163511173 0.166270327 1.802049636 0.300551271 FBgn0065160 l(3)SH044 lethal (3) SH044 http://flybase.org/reports/FBgn0065160 gene - - - "l(3)SH044, l(2)SH3 044" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005036 E(scalloped) Enhancer of scalloped http://flybase.org/reports/FBgn0005036 - gene - - - "E(scalloped), E(sd)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040800 CG13052 - http://flybase.org/reports/FBgn0040800 protein_coding_gene - - - CG13052 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267129 CR45569 - http://flybase.org/reports/FBgn0267129 non_protein_coding_gene - - - CR45569 - CR45569 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082342 HM530 HM530 http://flybase.org/reports/FBgn0082342 gene - - - HM530 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036367 CG10116 - http://flybase.org/reports/FBgn0036367 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available CG10116 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG10116 11-Aug-17 DroID_v2017_08 "Drer\LOC101884800, Drer\LOC100331214, Drer\lipia, Drer\lipib, Drer\pla1a, Drer\lpl, Drer\lipg, Drer\lipca" - - "Xtro\lpl, Xtro\lipg" "Mmus\Lipg, Mmus\Lipi, Mmus\Pnliprp1, Mmus\Pnlip, Mmus\Lipc, Mmus\Lpl, Mmus\Pla1a, Mmus\Liph, Mmus\Pnliprp2" "Hsap\PNLIPRP3, Hsap\PNLIP, Hsap\LIPG, Hsap\PNLIPRP1, Hsap\PNLIPRP2, Hsap\LIPH, Hsap\PLA1A, Hsap\LIPI, Hsap\LPL, Hsap\LIPC" viable FBgn0013653 ms(2)LY1 ms(2)LY1 http://flybase.org/reports/FBgn0013653 - gene - - - ms(2)LY1 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0261803 CG42749 - http://flybase.org/reports/FBgn0261803 protein_coding_gene - - - "CG42749, CG15785, CG15786" "IPR004302:Cellulose/chitin-binding protein, N-terminal" CG42749 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036128 Elo68beta Elongase 68beta http://flybase.org/reports/FBgn0036128 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "Elo68beta, CG11801, elo68beta" "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG11801 11-Aug-17 DroID_v2017_08 "Drer\elovl1a, Drer\zgc:101858, Drer\dhrs7, Drer\elovl7a, Drer\hsd17b8, Drer\elovl1b, Drer\elovl7b, Drer\elovl5, Drer\elovl4a, Drer\elovl4b, Drer\elovl8a, Drer\elovl8b, Drer\elovl2" "Scer\ELO3, Scer\ELO1, Scer\ELO2" "Cele\Y47G6A.21, Cele\ZK829.1, Cele\dhs-14, Cele\elo-6, Cele\elo-7, Cele\elo-3, Cele\F28H7.2, Cele\elo-4, Cele\dhs-25, Cele\elo-1, Cele\F26D2.15, Cele\Y47G6A.22, Cele\F25D1.5, Cele\dhs-11, Cele\C06E4.3, Cele\elo-5" "Xtro\cbr4, Xtro\dhrs7, Xtro\elovl7, Xtro\hsd17b8, Xtro\MGC79752, Xtro\elovl2, Xtro\elovl5, Xtro\elovl1" "Mmus\Elovl4, Mmus\Elovl5, Mmus\H2-Ke6, Mmus\Elovl2, Mmus\Cbr4, Mmus\Elovl7, Mmus\Elovl1, Mmus\Elovl6, Mmus\Dhrs7" "Hsap\ELOVL5, Hsap\ELOVL1, Hsap\ELOVL7, Hsap\HSD17B8, Hsap\ELOVL6, Hsap\DHRS7, Hsap\CBR4, Hsap\ELOVL4, Hsap\ELOVL2" viable FBgn0022008 l(2)k09216 lethal (2) k09216 http://flybase.org/reports/FBgn0022008 - gene - - - l(2)k09216 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050005 GstT2 Glutathione S transferase T2 http://flybase.org/reports/FBgn0050005 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG12930A, CG12930, GstT2, gstt2, CG30005, GSTT2, DmGSTT2" "IPR004046:Glutathione S-transferase, C-terminal, IPR004045:Glutathione S-transferase, N-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG30005 11-Aug-17 DroID_v2017_08 "Drer\gstt1a, Drer\gstt2, Drer\mars, Drer\eef1g, Drer\gstr, Drer\vars, Drer\eef1e1, Drer\gstt1b" "Scer\GTT2, Scer\GTT1, Scer\TEF4, Scer\CAM1, Scer\YGR201C, Scer\URE2" "Cele\gst-29, Cele\gst-21" "Xtro\gstt1, Xtro\eef1e1, Xtro\eef1g" "Mmus\Eef1e1, Mmus\Mars, Mmus\Gstt3, Mmus\Eef1g, Mmus\Vars, Mmus\Gstt4, Mmus\Gstt2, Mmus\Gstt1" "Hsap\GSTT2, Hsap\VARS, Hsap\GSTT1, Hsap\EEF1G, Hsap\GSTT2B, Hsap\MARS, Hsap\EEF1E1" viable DRSC06244 E -0.287351328 0.204748138 1.611984003 -0.056901396 -0.242746207 0.869418729 FBgn0028847 CG9014 - http://flybase.org/reports/FBgn0028847 protein_coding_gene "protein tag ; GO:0031386 | inferred from electronic annotation with InterPro:IPR015036 acid-amino acid ligase activity ; GO:0016881 | inferred from electronic annotation with InterPro:IPR015036 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR013323 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:18401 zinc ion binding ; GO:0008270 | inferred from sequence model" protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:18401 cellular_component ; GO:0005575 | no biological data available "DS08249.3, BG:DS08249.3, CG9014" "IPR001841:Zinc finger, RING-type, IPR008974:TRAF-like, IPR015036:USP8 interacting, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR003613:U box domain" CG9014 11-Aug-17 DroID_v2017_08 "Drer\rnf151, Drer\rnf41l, Drer\rnf41" - Cele\C55A6.1 Xtro\rnf41 "Mmus\Rnf138, Mmus\Rnf41, Mmus\Rnf151" "Hsap\RNF41, Hsap\RNF138, Hsap\RNF151" viable FBgn0010407 Ror Ror http://flybase.org/reports/FBgn0010407 FBgn0022797 protein_coding_gene "transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from electronic annotation with InterPro:IPR002011 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002011, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement" "transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from electronic annotation with InterPro:IPR002011 protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR002011, InterPro:IPR008266, InterPro:IPR020635 protein phosphorylation ; GO:0006468 | non-traceable author statement central nervous system development ; GO:0007417 | inferred from expression pattern" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002011 integral component of membrane ; GO:0016021 | non-traceable author statement "Dror, CG4926, DmHD-2, ROR, DRor, HD-2, Ror, ROR1" "IPR018056:Kringle, conserved site, IPR000001:Kringle, IPR000719:Protein kinase domain, IPR002011:Tyrosine-protein kinase, receptor class II, conserved site, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013806:Kringle-like fold, IPR017441:Protein kinase, ATP binding site, IPR020067:Frizzled domain, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG4926 11-Aug-17 DroID_v2017_08 "Drer\ntrk1, Drer\ntrk2a, Drer\ntrk3b, Drer\ntrk2b, Drer\ror2, Drer\ntrk3a, Drer\ror1" - "Cele\kin-16, Cele\old-2, Cele\kin-23, Cele\ver-4, Cele\kin-30, Cele\R09D1.13, Cele\Y50D4B.6, Cele\W04G5.10, Cele\cam-1, Cele\ver-1, Cele\old-1, Cele\kin-15, Cele\ver-3, Cele\T01G5.1, Cele\R09D1.12" "Xtro\musk, Xtro\ror1, Xtro\ntrk1, Xtro\ror2" "Mmus\Ntrk3, Mmus\Ptk7, Mmus\Ntrk1, Mmus\Ntrk2, Mmus\Ror1, Mmus\Ror2" "Hsap\ROR2, Hsap\NTRK3, Hsap\NTRK2, Hsap\ROR1, Hsap\PTK7" " embryonic stage | stage >=11 , embryonic stage " " central nervous system

, embryonic peripheral nervous system | restricted

" viable FBgn0263387 CG43439 - http://flybase.org/reports/FBgn0263387 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43439 - CG43439 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063494 GstE6 Glutathione S transferase E6 http://flybase.org/reports/FBgn0063494 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG17530, CT38747, DmGSTE6, GstE6, GSTE6, E6, gste6, gstE6" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17530 11-Aug-17 DroID_v2017_08 "Drer\eef1g, Drer\eef1e1, Drer\gstt2, Drer\vars, Drer\gstt1b, Drer\gstr, Drer\mars, Drer\gstt1a" "Scer\TEF4, Scer\YGR201C, Scer\CAM1, Scer\GTT2, Scer\GTT1, Scer\URE2" "Cele\gst-44, Cele\gst-21, Cele\gsto-3, Cele\gst-29, Cele\C02D5.4, Cele\gsto-2" "Xtro\gstt1, Xtro\gsto1, Xtro\eef1e1, Xtro\eef1g" "Mmus\Gstt4, Mmus\Mars, Mmus\Eef1e1, Mmus\Eef1g, Mmus\Gsto1, Mmus\Gstt2, Mmus\Gstt1, Mmus\Gstt3, Mmus\Vars" "Hsap\VARS, Hsap\EEF1G, Hsap\GSTT2, Hsap\GSTO1, Hsap\GSTO2, Hsap\EEF1E1, Hsap\GSTT1, Hsap\GSTT2B, Hsap\MARS" DRSC06676 K -0.416586668 0.273022853 -0.119957201 0.504020855 -1.973981852 0.016004427 FBgn0039561 mfrn mitoferrin http://flybase.org/reports/FBgn0039561 protein_coding_gene iron ion transmembrane transporter activity ; GO:0005381 | inferred from direct assay iron ion transmembrane transporter activity ; GO:0005381 | inferred from biological aspect of ancestor with PANTHER:PTN000641807 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 multicellular organismal iron ion homeostasis ; GO:0060586 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype mitochondrial iron ion transport ; GO:0048250 | inferred from biological aspect of ancestor with PANTHER:PTN000641807 mitochondrial iron ion transport ; GO:0048250 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000641807 mitochondrial inner membrane ; GO:0005743 | inferred from direct assay "anon-EST:fe2H5, mfrn, HD35059, dmfrn, CG4963, Mfrn" "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG4963 11-Aug-17 DroID_v2017_08 "Drer\slc25a28, Drer\slc25a37" "Scer\MRS4, Scer\MRS3" Cele\mfn-1 "Xtro\slc25a28, Xtro\slc25a37" "Mmus\Slc25a37, Mmus\Slc25a28, Mmus\Gm16867, Mmus\Entpd4" "Hsap\SLC25A28, Hsap\SLC25A37" "male sterile,recessive,female fertile,partially lethal - majority die,some die during pupal stage,viable,fertile" "spermatozoon,elongation stage spermatid,mitochondrial derivative,spermatid cyst" FBgn0044395 Scim33 Sensitized chromosome inheritance modifier 33 http://flybase.org/reports/FBgn0044395 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim33 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0011158 l(1)Q236 lethal (1) Q236 http://flybase.org/reports/FBgn0011158 FBgn0010210 gene - - - l(1)Q236 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263902 M7.S - http://flybase.org/reports/FBgn0263902 gene - - - M7.S - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0065429 l(2)SH1499 lethal (2) SH1499 http://flybase.org/reports/FBgn0065429 gene - - - "l(2)SH1499, l(2)SH2 1499" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037292 plh pasang lhamu http://flybase.org/reports/FBgn0037292 protein_coding_gene - response to hypoxia ; GO:0001666 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 "CG2022, plh" IPR007248:Mpv17/PMP22 CG2022 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-72e1.7, Drer\mpv17, Drer\pxmp2, Drer\mpv17l2, Drer\si:ch211-120k19.1" "Scer\SYM1, Scer\YOR292C" - "Xtro\pxmp2, Xtro\mpv17l2" "Mmus\Mpv17, Mmus\Mpv17l2, Mmus\Pxmp2, Mmus\Mpv17l" "Hsap\PXMP2, Hsap\MPV17, Hsap\MPV17L, Hsap\MPV17L2" viable FBgn0011840 tRNA:Ala-AGC-2-3 transfer RNA:Alanine-AGC 2-3 http://flybase.org/reports/FBgn0011840 "FBgn0051574, FBgn0060278" tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "tRNA[Ala], Ala, AE002708.trna50-AlaAGC, tRNA:A:AGC:AE002708-k, tRNA:ala:90C, CR31574, tRNA[[Ala]], chr3R.trna56-AlaAGC, tRNA-Ala-AGC-2-3, tRNA:Ala-AGC-2-3, tRNA:A:90C, GCU" - CR31574 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058205 CG40205 - http://flybase.org/reports/FBgn0058205 protein_coding_gene - - - CG40205 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005518 l(1)2Di lethal (1) 2Di http://flybase.org/reports/FBgn0005518 - gene - - - "N6, l(1)N6, l(1)2Di" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263997 CG43740 - http://flybase.org/reports/FBgn0263997 protein_coding_gene molecular_function ; GO:0003674 | no biological data available lateral inhibition ; GO:0046331 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay "CG43740, CG15307, CG12641" - CG43740 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050410 Rpi Ribose-5-phosphate isomerase http://flybase.org/reports/FBgn0050410 protein_coding_gene ribose-5-phosphate isomerase activity ; GO:0004751 | inferred from biological aspect of ancestor with PANTHER:PTN000232507 "D-ribose metabolic process ; GO:0006014 | inferred from biological aspect of ancestor with PANTHER:PTN000232507 pentose-phosphate shunt, non-oxidative branch ; GO:0009052 | inferred from biological aspect of ancestor with PANTHER:PTN000232507 age-dependent response to reactive oxygen species ; GO:0001315 | inferred from mutant phenotype" intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000232509 "CG30410, CG9872, Rpi, rpi" "IPR004788:Ribose 5-phosphate isomerase, type A" CG30410 11-Aug-17 DroID_v2017_08 Drer\rpia Scer\RKI1 Cele\rpia-1 Xtro\rpia Mmus\Rpia Hsap\RPIA "oxidative stress response defective,long lived,viable" FBgn0040529 COX7A Cytochrome c oxidase subunit 7A http://flybase.org/reports/FBgn0040529 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P24310 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProtKB:P24310" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P24310 "VIIa, CG9603, COXK, COXJ, COX7A, Cox7a" "IPR003177:Cytochrome c oxidase, subunit VIIa" CG9603 11-Aug-17 DroID_v2017_08 "Drer\cox7a2a, Drer\cox7a1, Drer\cox7a2b, Drer\cox7a3" - - "Xtro\cox7a2l, Xtro\cox7a2, Xtro\LOC100127850" "Mmus\Cox7a1, Mmus\Cox7a2, Mmus\Cox7a2l" "Hsap\COX7A2, Hsap\COX7A1, Hsap\COX7A2L" "viable,visible" "trichogen cell,mesothoracic tergum" DRSC16514 EK -1.032480596 -1.245219586 -1.763575084 -0.562674272 0.372743884 1.882061775 FBgn0060593 l(3)S092415b lethal (3) S092415b http://flybase.org/reports/FBgn0060593 gene - - - "0924/15, l(3)S092415b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000855 fs(1)M48 female sterile (1) M48 http://flybase.org/reports/FBgn0000855 - gene - - - fs(1)M48 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile chorion FBgn0058339 CG40339 - http://flybase.org/reports/FBgn0058339 protein_coding_gene - - - CG40339 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20981 E -0.792467696 -0.513502664 1.385064589 1.565609211 FBgn0259594 B0583 - http://flybase.org/reports/FBgn0259594 gene - - - B0583 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal wing FBgn0085545 CG40958 - http://flybase.org/reports/FBgn0085545 protein_coding_gene - - - CG40958 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024985 CG11448 - http://flybase.org/reports/FBgn0024985 - protein_coding_gene dynein light intermediate chain binding ; GO:0051959 | inferred from biological aspect of ancestor with PANTHER:PTN001088590 small GTPase binding ; GO:0031267 | inferred from biological aspect of ancestor with PANTHER:PTN001088590 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000948208 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001469871 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN000948208 "EG:132E8.4, CG11448" "IPR019143:JNK/Rab-associated protein-1, N-terminal, IPR034743:RH1 domain, IPR034744:RH2 domain" CG11448 11-Aug-17 DroID_v2017_08 "Drer\rilp, Drer\rilpl1, Drer\rilpl2" - "Cele\K01A2.10, Cele\rilp-1" "Xtro\rilpl1, Xtro\rilpl2" "Mmus\Rilpl2, Mmus\Rilpl1, Mmus\Rilp" "Hsap\RILPL2, Hsap\CEP83, Hsap\RILPL1, Hsap\CCDC92, Hsap\RILP" "viable,fertile" FBgn0036202 CG6024 - http://flybase.org/reports/FBgn0036202 protein_coding_gene - - - "CT18912, CG6024" "IPR000859:CUB domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site" CG6024 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0038071 Dtg Dpp target gene http://flybase.org/reports/FBgn0038071 protein_coding_gene - gastrulation ; GO:0007369 | inferred from expression pattern cell surface ; GO:0009986 | inferred from direct assay vesicle ; GO:0031982 | inferred from direct assay "CG6234, Dtg" - CG6234 11-Aug-17 DroID_v2017_08 "Drer\leo1, Drer\rp1" Scer\YFR016C - Xtro\leo1 "Mmus\Dmp1, Mmus\Leo1, Mmus\Ibsp, Mmus\Rp1" "Hsap\RP1, Hsap\DMP1, Hsap\IBSP, Hsap\LEO1" "lethal,visible" "embryonic head,germ band,crossvein,ectopic,wing" DRSC15998 K 0.312648607 0.23782767 0.366990237 0.293949921 0.976832397 1.670911511 FBgn0025792 Su(var)b301 Suppressor of variegation b301 http://flybase.org/reports/FBgn0025792 - gene - - - "Su-var(2)b301, Su(var)b301" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051235 CG31235 - http://flybase.org/reports/FBgn0051235 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - - "CG7117, CG14311, CG31235" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG31235 11-Aug-17 DroID_v2017_08 "Drer\ascc1, Drer\si:dkey-73n8.3, Drer\zgc:112332, Drer\cbr1l, Drer\cbr1, Drer\dhrs13a.1, Drer\rdh12, Drer\si:dkey-94e7.2, Drer\si:dkey-23o4.6, Drer\si:ch211-165b10.3, Drer\dhrs13a.2, Drer\dhrs13a.3, Drer\dhrsx, Drer\dhrs12, Drer\dhrs13l1, Drer\zgc:153441, Drer\rdh12l, Drer\si:dkey-174n20.1, Drer\rdh14a, Drer\rdh14b, Drer\zgc:64106, Drer\si:ch211-107o10.3, Drer\flj13639" "Scer\ENV9, Scer\YNL181W, Scer\YKL107W" - "Xtro\rdh13, Xtro\dhrsx, Xtro\rdh14, Xtro\rdh11, Xtro\dhrs12, Xtro\dhrs13, Xtro\ascc1" "Mmus\Dhrs13, Mmus\Cbr1, Mmus\Cbr3, Mmus\Rdh13, Mmus\Dhrsx, Mmus\Ascc1, Mmus\Rdh12, Mmus\Rdh11, Mmus\1700003E16Rik, Mmus\Rdh14, Mmus\Wwox" "Hsap\RDH11, Hsap\RDH13, Hsap\CBR3, Hsap\CBR1, Hsap\DHRS12, Hsap\OSTC, Hsap\DHRS13, Hsap\C2orf81, Hsap\RDH14, Hsap\DHRSX, Hsap\RDH12" viable FBgn0030174 CG15312 - http://flybase.org/reports/FBgn0030174 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "CT35293, CG15312" "IPR003598:Immunoglobulin subtype 2, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype" CG15312 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267764 CR46095 - http://flybase.org/reports/FBgn0267764 non_protein_coding_gene - - - CR46095 - CR46095 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033599 CG13223 - http://flybase.org/reports/FBgn0033599 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004837 CG13223 IPR004837:Sodium/calcium exchanger membrane region CG13223 11-Aug-17 DroID_v2017_08 "Drer\slc8b1, Drer\slc24a4b" "Scer\ECM27, Scer\YDL206W" "Cele\ncx-10, Cele\ncx-9, Cele\ncx-7, Cele\ncx-8, Cele\ncx-6" Xtro\slc8b1 "Mmus\Slc24a4, Mmus\Slc8b1, Mmus\Slc24a3" "Hsap\SLC24A3, Hsap\SLC8B1, Hsap\SLC24A4" viable FBgn0033665 Zip48C Zinc/iron regulated transporter-related protein 48C http://flybase.org/reports/FBgn0033665 protein_coding_gene metal ion transmembrane transporter activity ; GO:0046873 | inferred from electronic annotation with InterPro:IPR003689 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003689 metal ion transport ; GO:0030001 | inferred from electronic annotation with InterPro:IPR003689 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003689 "CG13189, dZip48C, Zip48C, cg13189" IPR003689:Zinc/iron permease CG13189 11-Aug-17 DroID_v2017_08 Drer\slc39a11 Scer\ZRT3 Cele\F59A3.4 Xtro\slc39a11 Mmus\Slc39a11 Hsap\SLC39A11 "viable,fertile" FBgn0050250 tRNA:His-GTG-1-2 transfer RNA:Histidine-GTG 1-2 http://flybase.org/reports/FBgn0050250 tRNA_gene CAC codon-amino acid adaptor activity ; GO:0033426 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033426 cytosol ; GO:0005829 | inferred by curator from GO:0033426 "AE002787.trna20-HisGTG, tRNA:H:GTG:AE002787-c, CR30250, tRNA[His], chr2R.trna79-HisGTG, tRNA-His-GTG-1-2, tRNA:His-GTG-1-2, tRNA:CR30250, CAC" - CR30250 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265874 CR44663 - http://flybase.org/reports/FBgn0265874 non_protein_coding_gene - - - "lincRNA.999, CR44663" - CR44663 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010107 daeh daeh http://flybase.org/reports/FBgn0010107 - gene molecular_function ; GO:0003674 | no biological data available head involution ; GO:0008258 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available daeh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic head,cephalopharyngeal skeleton,embryonic epidermis,dorsal" FBgn0024655 l(2)k08136 lethal (2) k08136 http://flybase.org/reports/FBgn0024655 - gene - - - "81/36, l(2)k08136" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0052246 CG32246 - http://flybase.org/reports/FBgn0052246 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32246 - CG32246 11-Aug-17 DroID_v2017_08 Drer\ndc1 - Cele\npp-22 Xtro\ndc1 Mmus\Ndc1 Hsap\NDC1 "viable,planar polarity defective" FBgn0044037 Mod(rst)B42 Mod(rst)B42 http://flybase.org/reports/FBgn0044037 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B42, Mod(rst)B42" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0261835 CR42767 - http://flybase.org/reports/FBgn0261835 non_protein_coding_gene - - - CR42767 - CR42767 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085314 CR34285 - http://flybase.org/reports/FBgn0085314 pseudogene_attribute - - - CR34285 - CR34285 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264637 constricted constricted http://flybase.org/reports/FBgn0264637 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - constricted - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval dorsal trunk,embryonic/larval tracheal system,eye,somatic clone" FBgn0024728 Slip1 Slip1 http://flybase.org/reports/FBgn0024728 FBgn0039919 protein_coding_gene potassium channel regulator activity ; GO:0015459 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q03720 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG1783, dSLIP1, Slip1" IPR001478:PDZ domain CG1783 11-Aug-17 DroID_v2017_08 "Drer\pdzrn3a, Drer\pdzrn4, Drer\si:dkey-61l1.4, Drer\pdzrn3b, Drer\pdzd4, Drer\lnx2b, Drer\LOC100001805" - Cele\C50F7.6 "Xtro\pdzrn4, Xtro\pdzd4, Xtro\pdzrn3" "Mmus\Pdzd4, Mmus\Pdzrn4, Mmus\Pdzrn3" "Hsap\PDZRN4, Hsap\PDZRN3, Hsap\PDZD4" viable FBgn0002825 ms(2)E4 male sterile (2) E4 http://flybase.org/reports/FBgn0002825 - gene - - - "ms2.4, ms(2)2.4, ms(2)E4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0039368 CG17196 - http://flybase.org/reports/FBgn0039368 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG17196, CG17196-PA" "IPR001594:Palmitoyltransferase, DHHC domain" CG17196 11-Aug-17 DroID_v2017_08 "Drer\zdhhc23a, Drer\zdhhc1, Drer\zdhhc12a, Drer\zdhhc21, Drer\zdhhc20a, Drer\zdhhc22, Drer\zdhhc5b, Drer\zdhhc8b, Drer\zdhhc5a, Drer\zdhhc23b, Drer\LOC100334198, Drer\zdhhc12b, Drer\zdhhc14, Drer\zdhhc24, Drer\zdhhc18a, Drer\zdhhc9, Drer\zdhhc3a, Drer\zgc:77880, Drer\zdhhc7, Drer\zdhhc20b, Drer\zdhhc3b" "Scer\PFA5, Scer\ERF2" "Cele\dhhc-10, Cele\dhhc-9, Cele\dhhc-1, Cele\dhhc-12" "Xtro\zdhhc12, Xtro\zdhhc8, Xtro\zdhhc24, Xtro\zdhhc1, Xtro\zdhhc7, Xtro\zdhhc21, Xtro\zdhhc9, Xtro\zdhhc14, Xtro\zdhhc3, Xtro\dnz1" "Mmus\Zdhhc19, Mmus\Zdhhc12, Mmus\Zdhhc25, Mmus\Zdhhc1, Mmus\Zdhhc20, Mmus\Zdhhc14, Mmus\Zdhhc11, Mmus\Zdhhc23, Mmus\Zdhhc8, Mmus\Zdhhc21, Mmus\Zdhhc22, Mmus\Zdhhc7, Mmus\Zdhhc5, Mmus\Zdhhc18, Mmus\Zdhhc24, Mmus\Zdhhc3, Mmus\Zdhhc9" "Hsap\ZDHHC19, Hsap\ZDHHC24, Hsap\ZDHHC5, Hsap\ZDHHC18, Hsap\ZDHHC20, Hsap\ZDHHC8, Hsap\ZDHHC22, Hsap\ZDHHC1, Hsap\ZDHHC7, Hsap\ZDHHC11, Hsap\ZDHHC14, Hsap\ZDHHC9, Hsap\ZDHHC3, Hsap\ZDHHC23, Hsap\ZDHHC12, Hsap\ZDHHC21" viable FBgn0011163 l(1)Q248 lethal (1) Q248 http://flybase.org/reports/FBgn0011163 FBgn0010210 gene - - - l(1)Q248 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015781 P5cr Pyrroline 5-carboyxlate reductase http://flybase.org/reports/FBgn0015781 - protein_coding_gene pyrroline-5-carboxylate reductase activity ; GO:0004735 | inferred from electronic annotation with InterPro:IPR000304 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000304, InterPro:IPR008927 proline biosynthetic process ; GO:0006561 | inferred from electronic annotation with InterPro:IPR000304" - "P5CR, CG6009, P5cr" "IPR000304:Pyrroline-5-carboxylate reductase, IPR016040:NAD(P)-binding domain, IPR029036:Pyrroline-5-carboxylate reductase, dimerisation domain, IPR028939:Pyrroline-5-carboxylate reductase, catalytic, N-terminal, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like" CG6009 11-Aug-17 DroID_v2017_08 "Drer\pycr1b, Drer\pycr1a, Drer\pycrl, Drer\pycr1" Scer\PRO3 "Cele\M153.1, Cele\F55G1.9" Xtro\pycr1 "Mmus\Pycr1, Mmus\Pycr2, Mmus\Noxred1, Mmus\Pycrl" "Hsap\PYCR2, Hsap\PYCRL, Hsap\PYCR1, Hsap\NOXRED1" viable FBgn0036320 CG10943 - http://flybase.org/reports/FBgn0036320 protein_coding_gene - - - "CG10943, Q9VU21" - CG10943 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010792 l(3)03076 lethal (3) 03076 http://flybase.org/reports/FBgn0010792 - gene - - - l(3)03076 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267599 CR45937 - http://flybase.org/reports/FBgn0267599 non_protein_coding_gene - - - "CR45937, lincRNA.600" - CR45937 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039370 CG4956 - http://flybase.org/reports/FBgn0039370 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG4956 "IPR001594:Palmitoyltransferase, DHHC domain" CG4956 11-Aug-17 DroID_v2017_08 "Drer\zdhhc12b, Drer\zgc:77880, Drer\zdhhc23a, Drer\zdhhc8b, Drer\zdhhc3b, Drer\zdhhc9, Drer\zdhhc5b, Drer\zdhhc1, Drer\zdhhc3a, Drer\zdhhc23b, Drer\zdhhc18a, Drer\zdhhc4, Drer\zdhhc5a, Drer\zdhhc21, Drer\zdhhc14, Drer\zdhhc22, Drer\zdhhc24, Drer\zdhhc12a, Drer\LOC100334198, Drer\zdhhc7" "Scer\PFA4, Scer\PFA5, Scer\ERF2, Scer\SWF1" "Cele\dhhc-10, Cele\dhhc-8, Cele\dhhc-11, Cele\dhhc-1, Cele\dhhc-12" "Xtro\zdhhc14, Xtro\dnz1, Xtro\zdhhc9, Xtro\zdhhc24, Xtro\zdhhc1, Xtro\zdhhc7, Xtro\zdhhc8, Xtro\zdhhc3, Xtro\zdhhc21, Xtro\zdhhc12" "Mmus\Zdhhc19, Mmus\Zdhhc9, Mmus\Zdhhc25, Mmus\Zdhhc14, Mmus\Zdhhc23, Mmus\Zdhhc21, Mmus\Zdhhc1, Mmus\Zdhhc11, Mmus\Zdhhc3, Mmus\Zdhhc7, Mmus\Zdhhc24, Mmus\Zdhhc5, Mmus\Zdhhc12, Mmus\Zdhhc18, Mmus\Zdhhc4, Mmus\Zdhhc22, Mmus\Zdhhc8" "Hsap\ZDHHC1, Hsap\ZDHHC3, Hsap\ZDHHC18, Hsap\ZDHHC24, Hsap\ZDHHC22, Hsap\ZDHHC7, Hsap\ZDHHC5, Hsap\ZDHHC9, Hsap\ZDHHC23, Hsap\ZDHHC11, Hsap\ZDHHC4, Hsap\ZDHHC21, Hsap\ZDHHC12, Hsap\ZDHHC14, Hsap\ZDHHC19, Hsap\ZDHHC8" viable FBgn0060885 l(3)S044738 lethal (3) S044738 http://flybase.org/reports/FBgn0060885 gene - - - "0447/38, l(3)S044738" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065187 l(2)SH2345 lethal (2) SH2345 http://flybase.org/reports/FBgn0065187 gene - - - "l(2)SH2345, l(2)SH2 2345" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267827 CR46148 - http://flybase.org/reports/FBgn0267827 non_protein_coding_gene - - - CR46148 - CR46148 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038312 Zip88E Zinc/iron regulated transporter-related protein 88E http://flybase.org/reports/FBgn0038312 protein_coding_gene metal ion transmembrane transporter activity ; GO:0046873 | inferred from electronic annotation with InterPro:IPR003689 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003689 metal ion transport ; GO:0030001 | inferred from electronic annotation with InterPro:IPR003689 basolateral plasma membrane ; GO:0016323 | inferred from direct assay "dZip88E, CG4334, Zip88E, cg4334" IPR003689:Zinc/iron permease CG4334 11-Aug-17 DroID_v2017_08 "Drer\slc39a1, Drer\slc39a3" "Scer\ZRT1, Scer\ZRT2, Scer\WSS1, Scer\YKE4" "Cele\F31C3.4, Cele\Y55F3BL.2, Cele\Y54G9A.4, Cele\C06G8.3, Cele\F55F8.9, Cele\C18A3.2, Cele\F30B5.7, Cele\tag-140" "Xtro\slc39a2, Xtro\slc39a1, Xtro\slc39a3, Xtro\slc39a1" "Mmus\Slc39a8, Mmus\Slc39a3, Mmus\Slc39a1, Mmus\Slc39a2" "Hsap\SLC39A8, Hsap\SLC39A3, Hsap\SLC39A1, Hsap\SLC39A2" "viable,fertile" FBgn0015852 anon-10Ce anon-10Ce http://flybase.org/reports/FBgn0015852 - gene - - - anon-10Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083055 snoRNA:Psi18S-1295 snoRNA:Psi18S-1295 http://flybase.org/reports/FBgn0083055 snoRNA_gene - - - "snoRNA:Psi18S-1295, psi18s-1295, Psi 18S-1295, CR34615, chr3R:16648312..16648503" - CR34615 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263903 l(3)OL24 - http://flybase.org/reports/FBgn0263903 gene - - - l(3)OL24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0066077 Stalker4\ORF1 Stalker4 element ORF1 http://flybase.org/reports/FBgn0066077 transposable_element_gene - - - "Stalker4\ORF1, ORF1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030151 CG1354 - http://flybase.org/reports/FBgn0030151 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR004396, InterPro:IPR006073, InterPro:IPR031167 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000592296" - cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000592296 CG1354 "IPR004396:Ribosome-binding ATPase YchF/Obg-like ATPase 1, IPR006073:GTP binding domain, IPR012676:TGS-like, IPR013029:Domain of unknown function DUF933, IPR012675:Beta-grasp domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR023192:TGS-like domain, IPR031167:OBG-type guanine nucleotide-binding (G) domain" CG1354 11-Aug-17 DroID_v2017_08 Drer\ola1 "Scer\OLA1, Scer\YGR210C, Scer\YLF2" Cele\ola-1 Xtro\ola1 Mmus\Ola1 Hsap\OLA1 viable FBgn0024371 E2f2 E2F transcription factor 2 http://flybase.org/reports/FBgn0024371 - protein_coding_gene "RNA polymerase II regulatory region DNA binding ; GO:0001012 | inferred from direct assay transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | contributes_to inferred from physical interaction with Rbf2 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24472 inferred from physical interaction with UniProtKB:Q9NIS1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24472 transcription factor binding ; GO:0008134 | inferred from physical interaction with Rbf2 protein heterodimerization activity ; GO:0046982 | inferred from direct assay" "negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from direct assay negative regulation of DNA replication ; GO:0008156 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay imaginal disc development ; GO:0007444 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype endomitotic cell cycle ; GO:0007113 | traceable author statement negative regulation of apoptotic process ; GO:0043066 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement G1/S transition of mitotic cell cycle ; GO:0000082 | traceable author statement oogenesis ; GO:0048477 | traceable author statement DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype inferred from genetic interaction with CycE" Rb-E2F complex ; GO:0035189 | inferred from direct assay Myb complex ; GO:0031523 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay "dE2F2, dE2f2, de2f2, E2F2, E2F, dE2F-2, CG1071, E2f2, e2f2, E2f" "IPR003316:E2F/DP family, winged-helix DNA-binding domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR015633:E2F Family" CG1071 11-Aug-17 DroID_v2017_08 "Drer\e2f4, Drer\si:ch211-160f23.5, Drer\si:ch211-195d17.2, Drer\e2f3, Drer\e2f5" - "Cele\efl-1, Cele\efl-2" "Xtro\e2f3, Xtro\e2f5, Xtro\e2f4, Xtro\e2f1" "Mmus\E2f3, Mmus\E2f5, Mmus\E2f6, Mmus\E2f1, Mmus\E2f2, Mmus\E2f4" "Hsap\E2F4, Hsap\E2F5, Hsap\E2F2, Hsap\E2F3, Hsap\E2F6, Hsap\E2F1" embryonic stage -- adult stage "female sterile,partially,viable,fertile,wild-type,male fertile,recessive,reduced,partially lethal - majority live,visible" "chorion,follicle cell & nucleus, with Df(2L)DS8, E2f21-188,follicle cell & nucleusDS8), with E2f21-188,follicle cell & nucleus, with E2f2329/Df(2L)DS8,follicle cell & nucleus, with Df(2L)DS8, E2f2329,follicle cell & nucleus, with Df(2L)DS8, E2f2k16402a,follicle cell & nucleus, with E2f2k16402a/Df(2L)DS8,follicle cell,follicle cell & nucleus,salivary gland & nucleus,eye,ommatidium" FBgn0002520 l(3)XaR lethal (3) XaR http://flybase.org/reports/FBgn0002520 - gene - - - l(3)XaR - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0019734 l(1)A10 lethal (1) A10 http://flybase.org/reports/FBgn0019734 - gene - - - l(1)A10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266747 CR45220 - http://flybase.org/reports/FBgn0266747 non_protein_coding_gene - - - CR45220 - CR45220 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015915 bk64 bk64 http://flybase.org/reports/FBgn0015915 - gene - - - bk64 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267930 CR46211 - http://flybase.org/reports/FBgn0267930 non_protein_coding_gene - - - "CR46211, lincRNA.1008" - CR46211 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036349 SNCF SoxNeuro Co-Factor http://flybase.org/reports/FBgn0036349 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with SoxN regulation of localization ; GO:0032879 | inferred from sequence or structural similarity with halo positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay nucleolus ; GO:0005730 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG14112, HL6, BcDNA:RE54375, SNCF, SCNF" IPR007970:Protein of unknown function DUF733 CG14112 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001860 l(1)VA335 lethal (1) VA335 http://flybase.org/reports/FBgn0001860 - gene - - - l(1)VA335 - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0021899 l(2)k12701 lethal (2) k12701 http://flybase.org/reports/FBgn0021899 - gene - - - l(2)k12701 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" crystal cell FBgn0052221 CG32221 - http://flybase.org/reports/FBgn0052221 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "anon-WO0118547.270, CG32221, FBXL18" "IPR032675:Leucine-rich repeat domain, L domain-like" CG32221 11-Aug-17 DroID_v2017_08 - - Cele\EEED8.10 Xtro\fbxl12 Mmus\Fbxl12 "Hsap\FBXL12, Hsap\FBXL13" viable FBgn0041195 Pkd2 Polycystic kidney disease 2 http://flybase.org/reports/FBgn0041195 protein_coding_gene cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with pyx calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from sequence or structural similarity with pyx spermatogenesis ; GO:0007283 | inferred from mutant phenotype sperm competition ; GO:0046692 | inferred from mutant phenotype detection of mechanical stimulus ; GO:0050982 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 larval feeding behavior ; GO:0030536 | inferred from mutant phenotype sperm storage ; GO:0046693 | inferred from mutant phenotype smooth muscle contraction ; GO:0006939 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with pyx "Amo, PKD2, Dmpkd2, amo, pkd2, CG6504, Pkd2, AMO, TRPP, TRPP2" "IPR013122:Polycystin cation channel, PKD1/PKD2" CG6504 11-Aug-17 DroID_v2017_08 "Drer\pkd1l3, Drer\dennd5a, Drer\pkd2, Drer\pkd2l1, Drer\loxhd1a, Drer\LOC100537993, Drer\dennd5b" - "Cele\lov-1, Cele\pkd-2" Xtro\pkd2 "Mmus\Pkd1, Mmus\Dennd5a, Mmus\Pkd2l2, Mmus\Dennd5b, Mmus\Pkd1l2, Mmus\Pkdrej, Mmus\Pkd1l3, Mmus\Pkd2l1, Mmus\Pkd2" "Hsap\PKDREJ, Hsap\DENND5A, Hsap\DENND5B, Hsap\PKD2L2, Hsap\PKD2, Hsap\PKD2L1, Hsap\PKD1" "male semi-sterile,feeding behavior defective,male sterile,partially,viable" "spermatozoon,flagellum (obsolete )" FBgn0000560 eg eagle http://flybase.org/reports/FBgn0000560 FBgn0000563 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay central nervous system development ; GO:0007417 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001628 "NR0A3, T1, egon, eag, EGON, spy, Egon, CG7383, eg, Eg, Egl, egl, eagle" "IPR001628:Zinc finger, nuclear hormone receptor-type, IPR013088:Zinc finger, NHR/GATA-type" CG7383 11-Aug-17 DroID_v2017_08 - - "Cele\nhr-7, Cele\nhr-179, Cele\nhr-3, Cele\nhr-119" - Mmus\Vdr Hsap\VDR " embryonic stage | stage 11-12 , embryonic stage | stage 14 " " neuroblast NB3-3

, neuroblast NB7-3

, neuroblast NB6-4

, neuroblast NB2-4

, dorsal fold

, embryonic central nervous system | presumptive | restricted

, neuroblast of ventral nerve cord primordium | subset

" "viable,visible,recessive,dominant,flightless,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,fertile" "wing,serotonergic neuron,EW1 neuron,serotonin neuron & ventral nerve cord,ventral nerve cord & serotonin neuron,neuroblast NB7-3,wing sensillum,ectopic,embryonic dorsal epidermis,dorsal closure embryo,embryonic/larval hemocyte | third instar larval stage" FBgn0032788 CG13084 - http://flybase.org/reports/FBgn0032788 protein_coding_gene - - chorion ; GO:0042600 | inferred from direct assay CG13084 - CG13084 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043898 gsb::Poxn gsb::Poxn http://flybase.org/reports/FBgn0043898 engineered_fusion_gene - - - "gsb::Pox-n, gsb::Poxn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible" "eye,adult head,antenna" FBgn0010596 l(2)05337 lethal (2) 05337 http://flybase.org/reports/FBgn0010596 - gene - - - l(2)05337 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264559 shf::Drer\wif1 - http://flybase.org/reports/FBgn0264559 engineered_fusion_gene - - - shf::Drer\wif1 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die "wing,wing margin bristle" FBgn0034200 Gbp2 Growth-blocking peptide 2 http://flybase.org/reports/FBgn0034200 protein_coding_gene cytokine activity ; GO:0005125 | inferred from sequence or structural similarity with Gbp1 N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001632117 signal transduction ; GO:0007165 | inferred from sequence or structural similarity with Gbp1 extracellular region ; GO:0005576 | inferred from direct assay "CG11395, Gbp2, gbp2" IPR032959:Diamine acetyltransferase 2 CG11395 11-Aug-17 DroID_v2017_08 "Drer\sat2a, Drer\sat2b, Drer\si:dkey-19b23.15, Drer\trim35-30" "Scer\HPA3, Scer\HPA2" - - "Mmus\Sat2, Mmus\Qrich2, Mmus\Satl1" "Hsap\SATL1, Hsap\QRICH2, Hsap\SAT2" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266058 Su(var)203 - http://flybase.org/reports/FBgn0266058 gene - - - "Su(var)203, 203" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0032590 CG4631 - http://flybase.org/reports/FBgn0032590 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4631 IPR031958:Protein of unknown function DUF4778 CG4631 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267497 28SrRNA:CR45837 28S ribosomal RNA:CR45837 http://flybase.org/reports/FBgn0267497 rRNA_gene - - - "28SrRNA:CR45837, CR45837" - CR45837 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001254 ImpE2 Ecdysone-inducible gene E2 http://flybase.org/reports/FBgn0001254 - protein_coding_gene - imaginal disc eversion ; GO:0007561 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay extrinsic component of membrane ; GO:0019898 | traceable author statement extracellular region ; GO:0005576 | inferred from direct assay "IMP-E2, Imp-E2, CG1934, ImpE2" - CG1934 11-Aug-17 DroID_v2017_08 - - - - - - " prepupal stage | 0-4 hr , embryonic stage | 12-15 hr , embryonic stage--pupal stage " " embryonic/larval proventriculus

, ectoderm

" embryonic stage | 12-15 hr ectoderm

viable FBgn0030258 CG1552 - http://flybase.org/reports/FBgn0030258 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model "anon-EST:Posey230, CG1552" - CG1552 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0040364 CG11378 - http://flybase.org/reports/FBgn0040364 protein_coding_gene - - - "EG:BACR42I17.2, CG11378" IPR009832:Protein of unknown function DUF1397 CG11378 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0262874 CG43229 - http://flybase.org/reports/FBgn0262874 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43229, chrX_18032634_18033088.0, lincRNA.1011, TCONS_00281284" - CG43229 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039696 CG7837 - http://flybase.org/reports/FBgn0039696 protein_coding_gene - - cytosol ; GO:0005829 | inferred from direct assay CG7837 "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR000225:Armadillo" CG7837 11-Aug-17 DroID_v2017_08 Drer\armc5 - Cele\T28F4.4 Xtro\armc5 Mmus\Armc5 Hsap\ARMC5 "viable,fertile" FBgn0084305 foil foiled coil http://flybase.org/reports/FBgn0084305 gene - - - foil - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030245 CG1637 - http://flybase.org/reports/FBgn0030245 protein_coding_gene "acid phosphatase activity ; GO:0003993 | inferred from electronic annotation with InterPro:IPR008963, InterPro:IPR015914 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008963, InterPro:IPR015914" biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG1637 "IPR025733:Iron/zinc purple acid phosphatase-like C-terminal domain, IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR008963:Purple acid phosphatase-like, N-terminal, IPR015914:Purple acid phosphatase, N-terminal, IPR003961:Fibronectin type III, IPR029052:Metallo-dependent phosphatase-like" CG1637 11-Aug-17 DroID_v2017_08 Drer\papl - "Cele\H25K10.1, Cele\Y105C5B.15, Cele\F21A3.11, Cele\F21A3.2, Cele\papl-1, Cele\Y105C5B.3, Cele\C08B6.14" Xtro\acp7 Mmus\Acp7 Hsap\ACP7 FBgn0002587 M(1)11F Minute (1) 11F http://flybase.org/reports/FBgn0002587 - gene - - - M(1)11F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038597 CG8064 - http://flybase.org/reports/FBgn0038597 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000457800 "neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000457800" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000457800 Pwp2p-containing subcomplex of 90S preribosome ; GO:0034388 | inferred from biological aspect of ancestor with PANTHER:PTN000457800 CG8064 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR007148:Small-subunit processome, Utp12" CG8064 11-Aug-17 DroID_v2017_08 Drer\wdr3 Scer\DIP2 Cele\F13H8.2 Xtro\wdr3 Mmus\Wdr3 Hsap\WDR3 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0005067 fs(2)OW208 female sterile (2) OW208 http://flybase.org/reports/FBgn0005067 - gene - - - fs(2)OW208 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031544 CG17593 - http://flybase.org/reports/FBgn0031544 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000306328 - cytoplasm ; GO:0005737 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000306328 CG17593 IPR012879:Protein of unknown function DUF1682 CG17593 11-Aug-17 DroID_v2017_08 Drer\ccdc47 Scer\YNR021W Cele\ccdc-47 Xtro\ccdc47 Mmus\Ccdc47 "Hsap\CCDC47, Hsap\STRADA" viable DRSC27490 K -0.138381969 0.353751013 0.132296996 0.622310441 2.479600671 2.567925918 FBgn0038743 CG11667 - http://flybase.org/reports/FBgn0038743 protein_coding_gene - - - CG11667 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043851 wwg wrinkled wing http://flybase.org/reports/FBgn0043851 gene - - - wwg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265940 CR44727 - http://flybase.org/reports/FBgn0265940 non_protein_coding_gene - - - CR44727 - CR44727 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051416 tRNA:Asp-GTC-3-1 transfer RNA:Aspartic acid-GTC 3-1 http://flybase.org/reports/FBgn0051416 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "AE002708.trna36-AspGTC, tRNA:D:GTC:AE002708-c, CR31416, tRNA[[Asp]], tRNA[Asp-GTC], chr3R.trna42-AspGTC, tRNA:Asp-GTC-3-1, tRNA:CR31416, tRNA-Asp-GTC-3-1, GAC" - CR31416 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015902 Ori93Falpha Ori93Falpha http://flybase.org/reports/FBgn0015902 - origin_of_replication - - - "oriDalpha, Ori93Falpha" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264954 fd3F forkhead domain 3F http://flybase.org/reports/FBgn0264954 protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR030456 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "CG44123, fd3F, CG12632, fd3f, CG32779, CG18771, CG15238, Fd3F" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR001766:Fork head domain, IPR030456:Fork head domain conserved site 2" CG44123 11-Aug-17 DroID_v2017_08 "Drer\foxn1, Drer\zgc:171734" "Scer\HCM1, Scer\FKH1, Scer\FHL1, Scer\FKH2" - - "Mmus\Foxr1, Mmus\Foxn1, Mmus\Foxr2" "Hsap\FOXN1, Hsap\FOXR2, Hsap\FOXR1" DRSC18160 K -0.012682742 -0.164782918 -0.15475681 0.239220993 2.289795239 -0.325215613 FBgn0027138 l(3)87Di lethal (3) 87Di http://flybase.org/reports/FBgn0027138 - gene - - - l(3)87Di - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264522 ff28 - http://flybase.org/reports/FBgn0264522 gene - - - ff28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" FBgn0250831 BG642167 - http://flybase.org/reports/FBgn0250831 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG34103, BG642167, BG642167(1a8), anon-SAGE:Wang-011, 1a8" - CG34103 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026373 RpII33 RNA polymerase II 33kD subunit http://flybase.org/reports/FBgn0026373 FBgn0001964 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001514 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR009025, InterPro:IPR011262 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000210281 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9189 inferred from sequence or structural similarity with SGD:S000001283" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9189 inferred from sequence or structural similarity with SGD:S000001283 cellular response to heat ; GO:0034605 | inferred from expression pattern "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9189 inferred from sequence or structural similarity with SGD:S000001283 nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity polytene chromosome puff ; GO:0005703 | inferred from direct assay" "Pol II RPII33, PolIIo, pol II, 152117_at, Pol II, RNAP, PolII, Rpll33, polII, RNA Pol II, rpII33, RNA pol II, CG7885, RNA polII, l(2)34Dg, RPB3, BG:DS00941.10, l(2)k05605, l34Dg, br17, l(2)br17, RpII33, Rpb3, D-rpII33, Rbp3, rpb3" "IPR001514:DNA-directed RNA polymerase, 30-40kDa subunit, conserved site, IPR009025:DNA-directed RNA polymerase, RBP11-like dimerisation domain, IPR011262:DNA-directed RNA polymerase, insert domain, IPR011263:DNA-directed RNA polymerase, RpoA/D/Rpb3-type" CG7885 11-Aug-17 DroID_v2017_08 Drer\polr2c Scer\RPB3 Cele\rpb-3 Xtro\polr2c Mmus\Polr2c Hsap\POLR2C "lethal,recessive" DRSC03415 IEK -1.394521917 2.807449998 1.804797464 -1.954444356 1.623100273 3.925555937 FBgn0266742 CR45215 - http://flybase.org/reports/FBgn0266742 non_protein_coding_gene - - - CR45215 - CR45215 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025777 homer homer http://flybase.org/reports/FBgn0025777 FBgn0026588 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Prosap "positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype adult behavior ; GO:0030534 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype regulation of locomotion ; GO:0040012 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from direct assay" endoplasmic reticulum ; GO:0005783 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay "Dm Homer, Dhomer, dhom, Dhom, LD03829, Dvh, CG11324, BEST:LD03829, homer, Homer, Hom" "IPR000697:WH1/EVH1 domain, IPR011993:PH domain-like" CG11324 11-Aug-17 DroID_v2017_08 "Drer\LOC100330028, Drer\homer2, Drer\homer3, Drer\homer1b" - - "Xtro\homer2, Xtro\homer3, Xtro\homer1" "Mmus\Homer1, Mmus\Homer2, Mmus\Homer3" "Hsap\HOMER3, Hsap\HOMER1, Hsap\HOMER2" "viable,partially lethal - majority die,visible,lethal,fertile,courtship behavior defective,male,recessive,hyperactive,smell perception defective,stress response defective,chemical sensitive,sleep defective" tarsal segment FBgn0027492 wdb widerborst http://flybase.org/reports/FBgn0027492 "FBgn0026590, FBgn0043349" protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from electronic annotation with InterPro:IPR002554 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002554 autophagy ; GO:0006914 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from direct assay spindle assembly ; GO:0051225 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay chromosome segregation ; GO:0007059 | inferred from mutant phenotype protein phosphatase type 2A complex ; GO:0000159 | inferred from electronic annotation with InterPro:IPR002554 "wdb, CG5643, B56-2, PP2A, PP2-AB, BcDNA:LD34343, EP3559, l(3)S031807, LD02456, 0318/07, BEST:LD02456, WDB, dPP2A, dB56-2, PP2a, Wdb, PP2A[B'-2], dPP2A-B56-2, PP2A-B'" "IPR002554:Protein phosphatase 2A, regulatory B subunit, B56, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG5643 11-Aug-17 DroID_v2017_08 "Drer\ppp2r5d, Drer\ppp2r5eb, Drer\ppp2r5ca, Drer\ppp2r5a, Drer\ppp2r5ea, Drer\ppp2r5cb, Drer\ppp2r5b" Scer\RTS1 "Cele\pptr-2, Cele\pptr-1" "Xtro\ppp2r5a, Xtro\ppp2r5c, Xtro\ppp2r5b, Xtro\ppp2r5e" "Mmus\Ppp2r5a, Mmus\Ppp2r5b, Mmus\Ppp2r5d, Mmus\Ppp2r5c, Mmus\Ppp2r5e" "Hsap\PPP2R5B, Hsap\PPP2R5D, Hsap\PPP2R5E, Hsap\PPP2R5C, Hsap\PPP2R5A" "visible,long lived,heat sensitive,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,neuroanatomy defective,locomotor rhythm defective,planar polarity defective,somatic clone,increased cell death,partially lethal - majority die,wild-type,viable" "eye,wing,wing hair,supernumerary,anterior fascicle & synapse,intersegmental nerve,trichogen cell,ectopic,tormogen cell,somatic clone,eye disc,tarsal segment" FBgn0028935 CG7653 - http://flybase.org/reports/FBgn0028935 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 aminopeptidase activity ; GO:0004177 | inferred from sequence or structural similarity metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "BG:DS00365.1, CG7653" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG7653 11-Aug-17 DroID_v2017_08 "Drer\anpepa, Drer\lnpep, Drer\anpepb, Drer\si:ch211-198g19.1, Drer\enpep, Drer\erap1b, Drer\si:ch211-149p5.1, Drer\si:ch211-276a23.5, Drer\erap1a, Drer\si:ch211-106j24.1, Drer\npepps, Drer\erap2" "Scer\TMA108, Scer\APE2, Scer\AAP1" "Cele\R03G8.4, Cele\Y42A5A.1, Cele\Y53F4B.20, Cele\AC3.5, Cele\pam-1, Cele\Y67D8C.9, Cele\F49B2.6, Cele\T07F10.1, Cele\mnp-1, Cele\VB0395L.1, Cele\R03G8.6, Cele\T12E12.6, Cele\T16G12.1" "Xtro\npepps, Xtro\lvrn, Xtro\anpep, Xtro\enpep, Xtro\erap1, Xtro\lnpep" "Mmus\Anpep, Mmus\Enpep, Mmus\Npepps, Mmus\Lnpep, Mmus\Lvrn, Mmus\Erap1, Mmus\Trhde" "Hsap\TRHDE, Hsap\ANPEP, Hsap\LNPEP, Hsap\ERAP2, Hsap\NPEPPS, Hsap\ERAP1, Hsap\LVRN, Hsap\ENPEP" viable FBgn0000764 fs(1)A572 female sterile (1) A572 http://flybase.org/reports/FBgn0000764 - gene - - - "fs(1)572, fs(1)A572" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,non-rescuable maternal effect,recessive,female sterile" "embryo,blastoderm embryo" FBgn0016948 tilE touch insensitive larva E http://flybase.org/reports/FBgn0016948 - gene - - - "line 375, tilE" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0000278 CecB Cecropin B http://flybase.org/reports/FBgn0000278 - protein_coding_gene - antibacterial humoral response ; GO:0019731 | inferred from sequence or structural similarity inferred from expression pattern defense response to bacterium ; GO:0042742 | traceable author statement humoral immune response ; GO:0006959 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay antibacterial humoral response ; GO:0019731 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CecB, CG1878, Cec, cecB, cec, crpB, cedcB, Cec B" "IPR000875:Cecropin, IPR020400:Cecropin, diptera" CG1878 11-Aug-17 DroID_v2017_08 - - - - - - larval stage embryonic/larval hemocyte

viable FBgn0060990 l(3)S027604b lethal (3) S027604b http://flybase.org/reports/FBgn0060990 gene - - - "0276/04, l(3)S027604b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027295 l(1)G0147 lethal (1) G0147 http://flybase.org/reports/FBgn0027295 - gene - - - l(1)G0147 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037635 CG9837 - http://flybase.org/reports/FBgn0037635 protein_coding_gene - - - CG9837 - CG9837 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085827 CR41621 - http://flybase.org/reports/FBgn0085827 rRNA_gene - - - CR41621 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086422 l(3)CHf lethal (3) CHf http://flybase.org/reports/FBgn0086422 gene - - - l(3)CHf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014231 l(2)31En lethal (2) 31En http://flybase.org/reports/FBgn0014231 - gene - - - l(2)31En - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069916 CG41136 - http://flybase.org/reports/FBgn0069916 protein_coding_gene - - - CG41136 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267211 CR45651 - http://flybase.org/reports/FBgn0267211 non_protein_coding_gene - - - CR45651 - CR45651 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031640 Mon1 Monensin sensitivity 1 http://flybase.org/reports/FBgn0031640 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000003092 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with SGD:S000003092 vesicle-mediated transport ; GO:0016192 | inferred from biological aspect of ancestor with PANTHER:PTN000315021 endosome to lysosome transport via multivesicular body sorting pathway ; GO:0032510 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000315021 synaptic cleft ; GO:0043083 | inferred from direct assay Mon1-Ccz1 complex ; GO:0035658 | inferred from sequence or structural similarity with SGD:S000003092 cytosol ; GO:0005829 | inferred from direct assay "Mon1, Dmon1, CG11926, MON1, NP_608868" IPR004353:Vacuolar fusion protein Mon1 CG11926 11-Aug-17 DroID_v2017_08 "Drer\mon1a, Drer\mon1ba, Drer\mon1bb" Scer\MON1 Cele\sand-1 Xtro\mon1a "Mmus\Mon1b, Mmus\Mon1a" "Hsap\MON1A, Hsap\MON1B" "partially lethal,recessive,viable" "endosome | somatic clone,multivesicular bodyhh-Gal4" FBgn0060865 l(3)S047322b lethal (3) S047322b http://flybase.org/reports/FBgn0060865 gene - - - "0473/22, l(3)S047322b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0050500 CG30500 - http://flybase.org/reports/FBgn0050500 protein_coding_gene - - - CG30500 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0277430 l(3)psg18 - http://flybase.org/reports/FBgn0277430 gene - - - "l(3)psg18, psg18" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061069 l(3)S018717b lethal (3) S018717b http://flybase.org/reports/FBgn0061069 gene - - - "0187/17, l(3)S018717b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0024713 anon-57Cn anon-57Cn http://flybase.org/reports/FBgn0024713 - gene - - - anon-57Cn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086399 BG02386 - http://flybase.org/reports/FBgn0086399 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02386 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0025573 PpN58A Protein phosphatase N at 58A http://flybase.org/reports/FBgn0025573 - protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006186 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity" protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from direct assay "PpN-58A, DmPpN-58A, PPN 58A, CG3245, PPN, PpN58A" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like, IPR031675:Serine-threonine protein phosphatase, N-terminal" CG3245 11-Aug-17 DroID_v2017_08 "Drer\ppp1cb, Drer\ppp1cbl" "Scer\PPZ1, Scer\PPZ2, Scer\PPQ1, Scer\GLC7" "Cele\ZK938.1, Cele\F58G1.3, Cele\F22D6.9, Cele\pph-1, Cele\Y69E1A.4, Cele\C34D4.2, Cele\Y71G12B.30, Cele\C30A5.4, Cele\C06A1.3, Cele\R13A5.11, Cele\T25B9.2, Cele\F52H3.6, Cele\F23B12.1, Cele\gsp-1" - Mmus\Ppp1cb Hsap\PPP1CB viable FBgn0040593 CG13824 - http://flybase.org/reports/FBgn0040593 protein_coding_gene - - - CG13824 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035266 Gk2 Glycerol kinase 2 http://flybase.org/reports/FBgn0035266 protein_coding_gene glycerol kinase activity ; GO:0004370 | inferred from sequence or structural similarity with HGNC:4289 glycerol kinase activity ; GO:0004370 | inferred from mutant phenotype glycerol-3-phosphate biosynthetic process ; GO:0046167 | inferred from sequence or structural similarity with HGNC:4289 glycerol-3-phosphate biosynthetic process ; GO:0046167 | inferred from mutant phenotype phosphorylation ; GO:0016310 | inferred from mutant phenotype glycerol metabolic process ; GO:0006071 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 triglyceride metabolic process ; GO:0006641 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 "CG7995, dGK, Gk2, Gk" "IPR005999:Glycerol kinase, IPR018483:Carbohydrate kinase, FGGY, conserved site, IPR018484:Carbohydrate kinase, FGGY, N-terminal, IPR018485:Carbohydrate kinase, FGGY, C-terminal, IPR000577:Carbohydrate kinase, FGGY" CG7995 11-Aug-17 DroID_v2017_08 "Drer\gk5, Drer\zgc:172295" Scer\GUT1 "Cele\C55B6.1, Cele\R11F4.1" Xtro\gk "Mmus\Gk2, Mmus\Gk, Mmus\Gk5, Mmus\Shpk, Mmus\Gykl1" "Hsap\GK, Hsap\GK2, Hsap\SHPK, Hsap\GK5" "chemical sensitive,viable" FBgn0062961 pncr016:2R putative noncoding RNA 016:2R http://flybase.org/reports/FBgn0062961 non_protein_coding_gene - - - "CR33942, BcDNA:RH09485, pncr016:2R, pncr016" - CR33942 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264083 CR43752 - http://flybase.org/reports/FBgn0264083 non_protein_coding_gene - - - CR43752 - CR43752 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023215 Mnt Mnt http://flybase.org/reports/FBgn0023215 "FBgn0024333, FBgn0029674" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with Myc protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Max inferred from physical interaction with Sin3A protein binding ; GO:0005515 | inferred from physical interaction with Max" "phagocytosis ; GO:0006909 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with Myc regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0003700 nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Mnt, dMnt, EG:114E2.2, Mad, dMad, CG2856, DmMnt, Mad-3E, dmnt, CG13316, mnt, bHLHe43, MNT" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG13316 11-Aug-17 DroID_v2017_08 "Drer\mxd3, Drer\mntb, Drer\mnta, Drer\mxi1" - Cele\mdl-1 "Xtro\mxd3, Xtro\mnt" "Mmus\Mxi1, Mmus\Mnt, Mmus\Mxd3" "Hsap\MNT, Hsap\MXI1, Hsap\MXD3" "viable,fertile,increased cell size,large body,short lived,visible,lethal,recessive,decreased cell size,somatic clone,starvation stress response defective" "wing hair,ommatidium,wing disc,somatic clone,wing,posterior compartment,adult head,eye,embryonic/larval fat body,mesothoracic tergum" FBgn0051957 CG31957 - http://flybase.org/reports/FBgn0051957 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR006196 translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR006196 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000493416 CG31957 "IPR006196:RNA-binding domain, S1, IF1 type, IPR012340:Nucleic acid-binding, OB-fold, IPR001253:Translation initiation factor 1A (eIF-1A)" CG31957 11-Aug-17 DroID_v2017_08 Drer\eif1ad - Cele\ZK856.11 Xtro\eif1ad Mmus\Eif1ad Hsap\EIF1AD viable FBgn0036690 Ilp8 Insulin-like peptide 8 http://flybase.org/reports/FBgn0036690 protein_coding_gene insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 cellular response to gamma radiation ; GO:0071480 | inferred from direct assay pupariation ; GO:0035073 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern regulation of developmental growth ; GO:0048638 | inferred from mutant phenotype determination of bilateral symmetry ; GO:0009855 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 chorion ; GO:0042600 | inferred by curator from GO:0007304 extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "dilp8, dILP8, CG14059, Ilp8, dlip8, DILP8, Dilp8, dILP-8" - CG14059 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,size defective,viable,large body" "wing,imaginal disc" FBgn0010726 l(3)00716 lethal (3) 00716 http://flybase.org/reports/FBgn0010726 - gene - - - l(3)00716 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0014961 fs(3)G1 female sterile (3) of Gill http://flybase.org/reports/FBgn0014961 - gene - - - "fs(3)1, fs(3)G1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male fertile,meiotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "syncytial blastoderm embryo,spindle" FBgn0010181 tu(2)91k tu(2)91k http://flybase.org/reports/FBgn0010181 - gene - - - "tu91k, tu-91k, tu(2)91k" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,visible,semidominant,female fertile,reduced" "melanotic mass,female" FBgn0070046 3L-61-3 3L-61-3 http://flybase.org/reports/FBgn0070046 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3L-61-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic abdominal segment,germline clone,maternal effect" FBgn0013479 l(1)1P3 lethal (1) 1P3 http://flybase.org/reports/FBgn0013479 - gene - - - l(1)1P3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,maternal effect,recessive,neurogenic phenotype" FBgn0261542 ms(2)35Dj male sterile (2) 35Dj http://flybase.org/reports/FBgn0261542 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(2)35Dj - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0267125 CR45565 - http://flybase.org/reports/FBgn0267125 non_protein_coding_gene - - - CR45565 - CR45565 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058216 CG40216 - http://flybase.org/reports/FBgn0058216 protein_coding_gene - - - CG40216 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070053 2L-311-30 2L-311-30 http://flybase.org/reports/FBgn0070053 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 2L-311-30 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "cephalopharyngeal skeleton,germline clone,maternal effect" FBgn0027939 sva53 sva53 http://flybase.org/reports/FBgn0027939 gene - - - sva53 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive,germline clone" FBgn0264620 fz2::otk - http://flybase.org/reports/FBgn0264620 engineered_fusion_gene - - - fz2::otk - - 11-Aug-17 DroID_v2017_08 - - - - - - "denticle,ectopic,embryonic/first instar larval cuticle" FBgn0263581 CR43606 - http://flybase.org/reports/FBgn0263581 non_protein_coding_gene - - - CR43606 - CR43606 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039048 CG17111 - http://flybase.org/reports/FBgn0039048 protein_coding_gene - cell morphogenesis ; GO:0000902 | inferred from sequence or structural similarity with dyl integral component of membrane ; GO:0016021 | inferred from sequence model CG17111 "IPR001507:Zona pellucida domain, IPR003609:PAN/Apple domain" CG17111 11-Aug-17 DroID_v2017_08 - - "Cele\cutl-16, Cele\cut-3, Cele\cutl-7, Cele\cutl-2, Cele\cutl-6, Cele\cutl-5, Cele\cutl-1, Cele\cut-6, Cele\cutl-8, Cele\cutl-17, Cele\cutl-10, Cele\cutl-18, Cele\cutl-29, Cele\cutl-24, Cele\cut-5, Cele\noah-1, Cele\F46G11.6, Cele\cutl-15, Cele\cutl-4, Cele\cutl-14, Cele\cutl-9, Cele\cut-1, Cele\dpy-1, Cele\cutl-3, Cele\cutl-20, Cele\T01D1.8, Cele\cutl-12, Cele\cutl-22, Cele\cutl-11, Cele\ram-5, Cele\cutl-25, Cele\cutl-13, Cele\cutl-28, Cele\cut-4, Cele\cutl-26, Cele\cutl-19" - - - viable FBgn0010682 l(2)s1976 lethal (2) s1976 http://flybase.org/reports/FBgn0010682 - gene - - - l(2)s1976 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011615 l(1)I33f3-1 lethal (1) I33f3-1 http://flybase.org/reports/FBgn0011615 FBgn0010206 gene - - - "l(1)33f3, l(1)I33f3-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022374 Pt-16 Larval protein-16 http://flybase.org/reports/FBgn0022374 - gene - - - Pt-16 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259126 agu aguesic http://flybase.org/reports/FBgn0259126 protein_coding_gene - - - agu - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014290 l(3)64Ba lethal (3) 64Ba http://flybase.org/reports/FBgn0014290 - gene - - - l(3)64Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015885 anon-64Bg anon-64Bg http://flybase.org/reports/FBgn0015885 - gene - - - anon-64Bg - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult head

FBgn0262893 CG43248 - http://flybase.org/reports/FBgn0262893 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43248 - CG43248 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023151 Su(mg)3-1 Suppressor of modifier of gypsy 3-1 http://flybase.org/reports/FBgn0023151 - gene - - - Su(mg)3-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002706 mei-1 meiotic 1 http://flybase.org/reports/FBgn0002706 - gene - - - mei-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030891 Ada3 transcriptional Adaptor 3 http://flybase.org/reports/FBgn0030891 protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001005430 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8I8V0 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay positive regulation of histone acetylation ; GO:0035066 | inferred from direct assay histone H4-K12 acetylation ; GO:0043983 | inferred from mutant phenotype histone H3-K9 acetylation ; GO:0043970 | inferred from mutant phenotype histone H3 acetylation ; GO:0043966 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from mutant phenotype histone H3-S10 phosphorylation ; GO:0043987 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001005430 histone H3-K14 acetylation ; GO:0044154 | inferred from mutant phenotype histone H4 acetylation ; GO:0043967 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from physical interaction with Spt3 polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay "dAda3, Ada3, HL-XIV, DADA3, CG7098, dADA3, ADA3, dik" IPR019340:Histone acetyltransferases subunit 3 CG7098 11-Aug-17 DroID_v2017_08 Drer\tada3l Scer\NGG1 - Xtro\tada3 Mmus\Tada3 Hsap\TADA3 "size defective,lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,non-enhancer of variegation,lethal,viable" "wing disc,germline cell,germline clone" DRSC20321 IK -0.015860604 1.510708513 -0.205271988 0.6411675 0.140543279 1.627589202 FBgn0023410 Ars-region44 Autonomous replicating sequence region 44 http://flybase.org/reports/FBgn0023410 - region - - - "dARS44, Ars-region44, Ars44" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060931 l(3)S041832 lethal (3) S041832 http://flybase.org/reports/FBgn0060931 gene - - - "0418/32, l(3)S041832" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033578 BBS4 Bardet-Biedl syndrome 4 http://flybase.org/reports/FBgn0033578 protein_coding_gene microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity with UniProtKB:Q96RK4 dynactin binding ; GO:0034452 | inferred from sequence or structural similarity with HGNC:969 non-motile cilium assembly ; GO:1905515 | inferred from electronic annotation with InterPro:IPR028786 centrosome organization ; GO:0051297 | inferred from sequence or structural similarity with UniProtKB:Q96RK4 cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern BBSome ; GO:0034464 | inferred from sequence or structural similarity with HGNC:969 pericentriolar material ; GO:0000242 | inferred from sequence or structural similarity with UniProtKB:Q96RK4 cilium ; GO:0005929 | inferred from sequence or structural similarity with HGNC:969 cilium ; GO:0005929 | inferred by curator from GO:0060271 "CG13232, BBS4" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR028786:Bardet-Biedl syndrome 4 protein" CG13232 11-Aug-17 DroID_v2017_08 Drer\bbs4 - Cele\bbs-4 Xtro\bbs4 Mmus\Bbs4 Hsap\BBS4 viable FBgn0265802 CR44591 - http://flybase.org/reports/FBgn0265802 non_protein_coding_gene - - - CR44591 - CR44591 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261174 ey::toy - http://flybase.org/reports/FBgn0261174 engineered_fusion_gene - - - ey::toy - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,ectopic,leg,antenna" FBgn0043858 pf-8 pairing failure-8 http://flybase.org/reports/FBgn0043858 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG8, pf-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002694 md melanotic lesions http://flybase.org/reports/FBgn0002694 - gene - - - md - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "head,thorax,abdomen" FBgn0014389 e(Pc)84DE e(Pc)84DE http://flybase.org/reports/FBgn0014389 - gene - - - "su(Pc)84DE, e(Pc)84DE, E(Pc)84DE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019869 EP115 EP115 http://flybase.org/reports/FBgn0019869 - gene - - - "anon-98Fa, EP115" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,partially lethal - majority die" eye FBgn0261968 huc2L-20 hydroxyurea- and (or) caffeine-sensitive 2L-20 http://flybase.org/reports/FBgn0261968 gene - - - "huc2L-20, huc[2L-20]" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,somatic clone,lethal" "eye,somatic clone,drug conditional" FBgn0036589 CG13067 - http://flybase.org/reports/FBgn0036589 protein_coding_gene - - - "anon-WO0153538.46, anon-WO0153538.39, CG13067" - CG13067 11-Aug-17 DroID_v2017_08 - - Cele\mltn-9 - - - viable FBgn0036606 CG13060 - http://flybase.org/reports/FBgn0036606 protein_coding_gene - - - "BcDNA:RE40431, CG13060" IPR007614:Retinin-like protein CG13060 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250821 CG14644 - http://flybase.org/reports/FBgn0250821 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001972 "CG14644, NEST:bs06h05" "IPR001107:Band 7 domain, IPR001972:Stomatin family" CG14644 11-Aug-17 DroID_v2017_08 "Drer\stom, Drer\stoml3a, Drer\stoml3b, Drer\stoml1, Drer\zgc:112408, Drer\nphs2" - "Cele\sto-2, Cele\sto-1, Cele\unc-1, Cele\mec-2, Cele\sto-4, Cele\sto-6, Cele\sto-3, Cele\sto-5" "Xtro\stoml3, Xtro\stoml1" "Mmus\Stoml1, Mmus\Stom, Mmus\Nphs2, Mmus\Stoml3" "Hsap\NPHS2, Hsap\STOML1, Hsap\STOML3, Hsap\STOM" FBgn0001659 l(1)ds13 lethal (1) discs small 13 http://flybase.org/reports/FBgn0001659 - gene - - - "l(1)1-48, l(1)ds13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,ring gland" FBgn0038595 CG7142 - http://flybase.org/reports/FBgn0038595 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP132, CG7142" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG7142 11-Aug-17 DroID_v2017_08 "Drer\zgc:92511, Drer\zgc:92590, Drer\hgfb, Drer\zmp:0000001088" - Cele\svh-1 - "Mmus\Try5, Mmus\Klk1b3, Mmus\Hgf, Mmus\1700074P13Rik" Hsap\HGF "partially lethal - majority die,some die during pupal stage" FBgn0028031 l(3)S102315 lethal (3) S102315 http://flybase.org/reports/FBgn0028031 gene - - - "1023/15, l(3)S102315" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025883 sax::tkv sax::tkv http://flybase.org/reports/FBgn0025883 - engineered_fusion_gene - - - sax::tkv - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260338 GSd429 - http://flybase.org/reports/FBgn0260338 gene - - - GSd429 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001453 l(1)7Dg lethal (1) 7Dg http://flybase.org/reports/FBgn0001453 - gene - - - "EM29, l(1)EM29, l(1)7Dg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0002754 mit(1)4 mitotic 4 http://flybase.org/reports/FBgn0002754 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0066373 avg avgust http://flybase.org/reports/FBgn0066373 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available avg - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0002712 mei-G87 meiotic G87 http://flybase.org/reports/FBgn0002712 - gene - - - mei-G87 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiotic cell cycle FBgn0052638 CG32638 - http://flybase.org/reports/FBgn0052638 protein_coding_gene - angiotensin-activated signaling pathway ; GO:0038166 | inferred from electronic annotation with InterPro:IPR009436 - CG32638 IPR009436:Type-1 angiotensin II receptor-associated protein CG32638 11-Aug-17 DroID_v2017_08 Drer\agtrap - - Xtro\agtrap Mmus\Agtrap Hsap\AGTRAP FBgn0265012 ed::shg - http://flybase.org/reports/FBgn0265012 engineered_fusion_gene - - - ed::shg - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell adhesion defective,cell autonomous" "wing disc,cell autonomous,somatic clone" FBgn0267967 corolla corolla http://flybase.org/reports/FBgn0267967 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B synaptonemal complex assembly ; GO:0007130 | inferred from mutant phenotype meiotic DNA double-strand break processing involved in reciprocal meiotic recombination ; GO:0010705 | inferred from mutant phenotype centromere clustering ; GO:0098653 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype synaptonemal complex ; GO:0000795 | inferred from direct assay "corolla, CG8316, mei-39" - CG8316 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051361 dpr17 defective proboscis extension response 17 http://flybase.org/reports/FBgn0051361 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG31361, Dpr-17, CG14738, CT34531, CG14737, dpr17, Dpr17" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold" CG31361 11-Aug-17 DroID_v2017_08 "Drer\kirrelb, Drer\kirrel3a, Drer\itgb4, Drer\si:dkey-65b12.12, Drer\igsf9bb, Drer\ncam1b, Drer\lrit3a, Drer\LOC101885444, Drer\si:ch1073-459j12.1, Drer\paplna, Drer\lrit1a, Drer\lrit3b, Drer\sdk1b, Drer\kirrel3l, Drer\lrit1b, Drer\ush2a, Drer\kirrela, Drer\LOC100333196, Drer\kirrel3b, Drer\sdk1a, Drer\igsf9a, Drer\dscama" - Cele\zig-8 "Xtro\igsf9b, Xtro\lrit3, Xtro\kirrel2, Xtro\papln" "Mmus\Igsf9b, Mmus\Ptprq, Mmus\Lrit3, Mmus\Lrit1, Mmus\Kirrel, Mmus\Kirrel3, Mmus\Kirrel2, Mmus\Sdk1, Mmus\Papln" "Hsap\LRIT3, Hsap\USH2A, Hsap\PAPLN, Hsap\KIRREL2, Hsap\KIRREL3, Hsap\KIRREL, Hsap\LRIT1, Hsap\SDK1, Hsap\IGSF9B" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0065272 l(2)SH2056 lethal (2) SH2056 http://flybase.org/reports/FBgn0065272 gene - - - "l(2)SH2056, l(2)SH2 2056" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0243499 l(3)CC00864 - http://flybase.org/reports/FBgn0243499 gene - - - l(3)CC00864 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004570 blnd bland http://flybase.org/reports/FBgn0004570 - gene - - - blnd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038355 CG4520 - http://flybase.org/reports/FBgn0038355 protein_coding_gene protein channel activity ; GO:0015266 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 CG4520 IPR027246:Eukaryotic porin/Tom40 CG4520 11-Aug-17 DroID_v2017_08 "Drer\tomm40, Drer\tomm40l" Scer\TOM40 Cele\tomm-40 Xtro\tomm40 "Mmus\Tomm40, Mmus\Tomm40l" "Hsap\TOMM40, Hsap\TOMM40L" viable FBgn0038495 CG14336 - http://flybase.org/reports/FBgn0038495 protein_coding_gene - - - CG14336 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041114 l(3)S028404b lethal (3) S028404b http://flybase.org/reports/FBgn0041114 gene - - - "0284/04, l(3)S028404, l(3)S028404b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032577 CG13244 - http://flybase.org/reports/FBgn0032577 protein_coding_gene - - - "BcDNA:GH27987, CG13244" - CG13244 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263458 snoRNA:CG43051-a - http://flybase.org/reports/FBgn0263458 snoRNA_gene - - - "snoRNA:CG43051-a, snoRNA:bun-a" - CR43573 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022748 anon-E8 anon-E8 http://flybase.org/reports/FBgn0022748 - gene - - - "E8, anon-E8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065666 l(2)SH0695 lethal (2) SH0695 http://flybase.org/reports/FBgn0065666 gene - - - "l(2)SH0695, l(2)SH2 0695" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034734 CG4554 - http://flybase.org/reports/FBgn0034734 protein_coding_gene - "neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000427367" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000427367 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000427367 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000427367 "CG4554, GM01751p" "IPR011430:Down-regulated-in-metastasis protein, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG4554 11-Aug-17 DroID_v2017_08 Drer\utp20 Scer\UTP20 Cele\utp-20 Xtro\utp20 Mmus\Utp20 Hsap\UTP20 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0011068 l(1)Q21 lethal (1) Q21 http://flybase.org/reports/FBgn0011068 FBgn0010210 gene - - - l(1)Q21 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263761 CG43678 - http://flybase.org/reports/FBgn0263761 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43678 - CG43678 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039367 CG17197 - http://flybase.org/reports/FBgn0039367 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG17197, CG17197-PA" "IPR001594:Palmitoyltransferase, DHHC domain" CG17197 11-Aug-17 DroID_v2017_08 "Drer\zdhhc12b, Drer\zdhhc5a, Drer\zdhhc20a, Drer\zdhhc18a, Drer\zdhhc12a, Drer\zdhhc14, Drer\zdhhc5b, Drer\zdhhc20b, Drer\zgc:77880, Drer\zdhhc8b, Drer\zdhhc24, Drer\zdhhc21, Drer\zdhhc23a, Drer\zdhhc3b, Drer\zdhhc3a, Drer\zdhhc1, Drer\zdhhc22, Drer\zdhhc9, Drer\zdhhc23b, Drer\zdhhc7, Drer\LOC100334198" "Scer\PFA5, Scer\ERF2" "Cele\dhhc-9, Cele\dhhc-10, Cele\dhhc-12, Cele\dhhc-1" "Xtro\dnz1, Xtro\zdhhc24, Xtro\zdhhc8, Xtro\zdhhc7, Xtro\zdhhc14, Xtro\zdhhc1, Xtro\zdhhc12, Xtro\zdhhc21, Xtro\zdhhc3, Xtro\zdhhc9" "Mmus\Zdhhc22, Mmus\Zdhhc25, Mmus\Zdhhc7, Mmus\Zdhhc13, Mmus\Zdhhc18, Mmus\Zdhhc12, Mmus\Zdhhc9, Mmus\Zdhhc5, Mmus\Zdhhc19, Mmus\Zdhhc14, Mmus\Zdhhc11, Mmus\Zdhhc23, Mmus\Zdhhc20, Mmus\Zdhhc8, Mmus\Zdhhc3, Mmus\Zdhhc24, Mmus\Zdhhc1, Mmus\Zdhhc21" "Hsap\ZDHHC11, Hsap\ZDHHC21, Hsap\ZDHHC1, Hsap\ZDHHC23, Hsap\ZDHHC3, Hsap\ZDHHC24, Hsap\ZDHHC13, Hsap\ZDHHC8, Hsap\ZDHHC18, Hsap\ZDHHC9, Hsap\ZDHHC19, Hsap\ZDHHC5, Hsap\ZDHHC22, Hsap\ZDHHC7, Hsap\ZDHHC12, Hsap\ZDHHC20, Hsap\ZDHHC14" viable FBgn0028598 l(2)k04301b lethal (2) k04301b http://flybase.org/reports/FBgn0028598 gene - - - l(2)k04301b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028122 l(3)S059011 lethal (3) S059011 http://flybase.org/reports/FBgn0028122 gene - - - "0590/11, l(3)S059011" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0083069 ozz ozzie http://flybase.org/reports/FBgn0083069 gene - - - ozz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067105 Gbeta13F::mira Gbeta13F::mira http://flybase.org/reports/FBgn0067105 engineered_fusion_gene - - - Gbeta13F::mira - - 11-Aug-17 DroID_v2017_08 - - - - - - spindleb FBgn0060989 l(3)S027614b lethal (3) S027614b http://flybase.org/reports/FBgn0060989 gene - - - "0276/14, l(3)S027614b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005756 l(1)TK313 lethal (1) TK313 http://flybase.org/reports/FBgn0005756 - gene - - - "l313, l(1)TK313" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0025841 E(var)183-31 E(var)183-31 http://flybase.org/reports/FBgn0025841 - gene - - - "E-183/31, E(var)183/31, E(var)183-31" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265014 S0279-04 - http://flybase.org/reports/FBgn0265014 gene - - - S0279-04 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053128 CG33128 - http://flybase.org/reports/FBgn0053128 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 lysosome ; GO:0005764 | inferred from electronic annotation with InterPro:IPR033144 "CG10872, CG33128" "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR033144:Cathepsin D, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG33128 11-Aug-17 DroID_v2017_08 "Drer\ctsd, Drer\zgc:103530, Drer\nots, Drer\zgc:63831, Drer\ren" "Scer\YPS3, Scer\YGL258W-A, Scer\PEP4, Scer\YPS7, Scer\YPS5, Scer\YPS6, Scer\MKC7, Scer\YPS1, Scer\BAR1" "Cele\asp-9, Cele\asp-5, Cele\asp-7, Cele\asp-18, Cele\asp-16, Cele\asp-12, Cele\asp-19, Cele\asp-1, Cele\asp-14, Cele\asp-2, Cele\asp-4, Cele\asp-3, Cele\asp-15, Cele\asp-13, Cele\asp-17, Cele\asp-10, Cele\asp-8, Cele\asp-6" "Xtro\ren, Xtro\pga4, Xtro\ctsd, Xtro\pgc, Xtro\LOC496913, Xtro\ctse, Xtro\napsa, Xtro\bace2, Xtro\bace1" "Mmus\Bace2, Mmus\Ctsd, Mmus\Ren2, Mmus\Napsa, Mmus\Pgc, Mmus\Bace1, Mmus\Ren1, Mmus\Pga5, Mmus\Cym, Mmus\Ctse" "Hsap\BACE2, Hsap\PGA4, Hsap\PGA3, Hsap\PGA5, Hsap\BACE1, Hsap\PGC, Hsap\CTSE, Hsap\REN, Hsap\CTSD, Hsap\NAPSA" viable FBgn0064912 CG31178 - http://flybase.org/reports/FBgn0064912 protein_coding_gene - - - "CG13414, CT32770, BEST:LP09246, BcDNA:LP09246, CG31178, Tes87, Dromel_CG31178_FBtr0084138_mORF" IPR019537:Transmembrane protein 65 CG31178 11-Aug-17 DroID_v2017_08 Drer\tmem65 - "Cele\tag-321, Cele\C03B8.3" - Mmus\Tmem65 Hsap\TMEM65 viable FBgn0024261 acd(2)5M8 auditory courtship defective 5M8 http://flybase.org/reports/FBgn0024261 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5M8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective,courtship behavior defective,male sterile" FBgn0028507 CG3793 - http://flybase.org/reports/FBgn0028507 protein_coding_gene protein C-terminal leucine carboxyl O-methyltransferase activity ; GO:0018423 | inferred from biological aspect of ancestor with PANTHER:PTN000340585 C-terminal protein methylation ; GO:0006481 | inferred from biological aspect of ancestor with PANTHER:PTN000340585 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001783984 "BG:DS09217.4, CG3793" "IPR007213:Methyltransferase Ppm1/Ppm2/Tcmp, IPR016651:Leucine carboxyl methyltransferase 1, LCMT1, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG3793 11-Aug-17 DroID_v2017_08 "Drer\tyw5, Drer\lcmt1, Drer\lcmt2" "Scer\PPM2, Scer\PPM1" Cele\B0285.4 "Xtro\lcmt2, Xtro\lcmt1" "Mmus\Lcmt2, Mmus\Lcmt1" "Hsap\TYW5, Hsap\LCMT2, Hsap\LCMT1" "viable,fertile" FBgn0016832 l(1)MZ19 lethal (1) MZ19 http://flybase.org/reports/FBgn0016832 - gene - - - "l(1)MZ19, M19" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266495 s-116 - http://flybase.org/reports/FBgn0266495 gene - - - s-116 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267177 CR45617 - http://flybase.org/reports/FBgn0267177 non_protein_coding_gene - - - CR45617 - CR45617 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038656 CG14294 - http://flybase.org/reports/FBgn0038656 protein_coding_gene - - - "BcDNA:AT18358, CG14294" - CG14294 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035697 CG10163 - http://flybase.org/reports/FBgn0035697 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype - CG10163 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG10163 11-Aug-17 DroID_v2017_08 "Drer\lipia, Drer\lipib, Drer\pla1a" "Scer\MND1, Scer\TVP15, Scer\NSE5" Cele\pdl-1 - "Mmus\Liph, Mmus\Pla1a, Mmus\Pde6d, Mmus\Lipi, Mmus\Pnliprp1, Mmus\Pnlip, Mmus\Pnliprp2" "Hsap\PNLIPRP3, Hsap\PNLIPRP1, Hsap\PDE6D, Hsap\LIPH, Hsap\PLA1A, Hsap\PNLIPRP2, Hsap\LIPI, Hsap\PNLIP" viable FBgn0266129 lov jim lovell http://flybase.org/reports/FBgn0266129 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" ventral midline development ; GO:0007418 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype larval walking behavior ; GO:0008346 | inferred from mutant phenotype negative gravitaxis ; GO:0048060 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 "CG16778, Tkr, 091y, 91Y, CG2672, tkr, BTB-III, dTKR, g2, anon-G2, BtbIII, Lov, TKR, lov" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR007889:DNA binding HTH domain, Psq-type, IPR009057:Homeobox domain-like" CG16778 11-Aug-17 DroID_v2017_08 - - - - - Hsap\ZBTB12 embryonic stage | stage 4-10 organism | dorso-lateral

FBgn0031197 CG17601 - http://flybase.org/reports/FBgn0031197 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17601 - CG17601 11-Aug-17 DroID_v2017_08 - - Cele\ensh-1 - - - viable FBgn0033963 CG12857 - http://flybase.org/reports/FBgn0033963 protein_coding_gene - - - CG12857 "IPR011333:SKP1/BTB/POZ domain, IPR011705:BTB/Kelch-associated, IPR031750:Domain of unknown function DUF4734" CG12857 11-Aug-17 DroID_v2017_08 Drer\klhl41a - - - - - "viable,fertile" FBgn0051070 tRNA:Gln-TTG-1-3 transfer RNA:Glutamine-TTG 1-3 http://flybase.org/reports/FBgn0051070 tRNA_gene CAA codon-amino acid adaptor activity ; GO:0033427 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033427 cytosol ; GO:0005829 | inferred by curator from GO:0033427 "AE002708.trna34-GlnTTG, tRNA:Q:TTG:AE002708-a, CR31070, chr3R.trna40-GlnTTG, tRNA:Gln-TTG-1-3, tRNA:CR31070, tRNA-Gln-TTG-1-3, CAA" - CR31070 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051436 CG31436 - http://flybase.org/reports/FBgn0051436 protein_coding_gene - - - "CG13660, CG31436" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31436 11-Aug-17 DroID_v2017_08 - - "Cele\nhr-246, Cele\C29F7.2, Cele\F59B1.10, Cele\H06H21.8, Cele\C29F7.1, Cele\D1044.1, Cele\dhs-27" - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" trichogen cell FBgn0021798 l(2)k17002 lethal (2) k17002 http://flybase.org/reports/FBgn0021798 - gene - - - l(2)k17002 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265196 CR44256 - http://flybase.org/reports/FBgn0265196 non_protein_coding_gene - - - CR44256 - CR44256 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031617 CG15635 - http://flybase.org/reports/FBgn0031617 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG15635 - CG15635 11-Aug-17 DroID_v2017_08 "Drer\zgc:103586, Drer\cda, Drer\e2f8, Drer\e2f7" - "Cele\cdd-2, Cele\cdd-1, Cele\Y53C10A.10" "Xtro\e2f8, Xtro\e2f7" "Mmus\E2f8, Mmus\Gm15114, Mmus\Maged2, Mmus\Maged1, Mmus\Magel2, Mmus\Cda, Mmus\Tro, Mmus\E2f7" "Hsap\TRO, Hsap\MAGED4B, Hsap\E2F8, Hsap\E2F7, Hsap\MAGED1, Hsap\MAGED2, Hsap\MAGED4, Hsap\CDA, Hsap\MAGEL2" "viable,fertile" FBgn0060577 l(3)S095209 lethal (3) S095209 http://flybase.org/reports/FBgn0060577 gene - - - "0952/09, l(3)S095209" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0084445 EP2012 EP2012 http://flybase.org/reports/FBgn0084445 gene - - - EP2012 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030690 CG12383 - http://flybase.org/reports/FBgn0030690 protein_coding_gene - - - CG12383 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085396 CG34367 - http://flybase.org/reports/FBgn0085396 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG34367, CG13141, CG5369" "IPR009057:Homeobox domain-like, IPR001356:Homeobox domain, IPR003654:OAR domain, IPR000047:Helix-turn-helix motif, IPR017970:Homeobox, conserved site" CG34367 11-Aug-17 DroID_v2017_08 "Drer\dmbx1a, Drer\hoxb8a, Drer\shox, Drer\mxtx2, Drer\ldb3a, Drer\pitx1, Drer\pitx3, Drer\pax6a, Drer\lhx6, Drer\pdlim3b, Drer\gsc, Drer\dmbx1b, Drer\shox2, Drer\pax6b, Drer\pdlim7" "Scer\PHO2, Scer\YHP1, Scer\PXL1, Scer\YOX1" "Cele\ceh-23, Cele\alp-1, Cele\lim-4, Cele\duxl-1, Cele\ceh-51, Cele\pha-2, Cele\vab-3, Cele\ceh-45" "Xtro\pitx3, Xtro\shox2, Xtro\gsc, Xtro\shox, Xtro\pdlim5, Xtro\hoxb8, Xtro\pitx1, Xtro\lhx8" "Mmus\Pitx1, Mmus\Dmbx1, Mmus\Lhx6, Mmus\Pitx3, Mmus\Pdlim1, Mmus\Pdlim5, Mmus\Lhx8, Mmus\Pdlim7, Mmus\Pdlim3, Mmus\Gsc2, Mmus\Shox2, Mmus\Pax6, Mmus\Ldb3, Mmus\Gsc" "Hsap\GSC2, Hsap\DMBX1, Hsap\SHOX2, Hsap\LHX6, Hsap\PAX6, Hsap\PDLIM3, Hsap\PITX3, Hsap\GSC, Hsap\PDLIM1, Hsap\LPXN, Hsap\PDLIM7, Hsap\LDB3, Hsap\LHX8, Hsap\SHOX, Hsap\HOXB8, Hsap\PITX1" FBgn0263757 Rpb4 RNA polymerase II subunit Rpb4 http://flybase.org/reports/FBgn0263757 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR010997 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from direct assay single-stranded RNA binding ; GO:0003727 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000480538 translation initiation factor binding ; GO:0031369 | inferred from biological aspect of ancestor with PANTHER:PTN000480538 single-stranded DNA binding ; GO:0003697 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000480538 protein binding ; GO:0005515 | inferred from physical interaction with Rpb7 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with UniProtKB:O15514 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9191 inferred from sequence or structural similarity with SGD:S000003676 "recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex ; GO:0034402 | inferred from biological aspect of ancestor with PANTHER:PTN000480538 polytene chromosome puffing ; GO:0035079 | NOT inferred from mutant phenotype positive regulation of translational initiation ; GO:0045948 | inferred from biological aspect of ancestor with PANTHER:PTN000480538 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | inferred from biological aspect of ancestor with PANTHER:PTN000480538 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with UniProtKB:O15514 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9191 inferred from sequence or structural similarity with SGD:S000003676 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay mRNA export from nucleus in response to heat stress ; GO:0031990 | inferred from biological aspect of ancestor with PANTHER:PTN000480538 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from biological aspect of ancestor with PANTHER:PTN000480538" "polytene chromosome chromocenter ; GO:0005701 | NOT inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000480538 polytene chromosome interband ; GO:0005705 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9191 inferred from sequence or structural similarity with SGD:S000003676 polytene chromosome ; GO:0005700 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with UniProtKB:O15514" "dAda2a, Ada2a, Rpb4, CG31237, RPB4, CG7150, DmRPB4, CG33520, dRpb4, DmRpb4, dRPB4" "IPR010997:HRDC-like, IPR005574:RNA polymerase II, Rpb4, IPR006590:RNA polymerase II, Rpb4, core" CG43662 11-Aug-17 DroID_v2017_08 Drer\polr2d Scer\RPB4 Cele\rpb-4 Xtro\polr2d "Mmus\Tada2a, Mmus\Polr2d" "Hsap\TADA2A, Hsap\POLR2D" "viable,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal,neuroanatomy defective" "ganglion mother cell,intestinal stem cell" FBgn0264385 CR43837 - http://flybase.org/reports/FBgn0264385 non_protein_coding_gene - - - CR43837 - CR43837 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261567 CG42681 - http://flybase.org/reports/FBgn0261567 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42681 - CG42681 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030244 CG2157 - http://flybase.org/reports/FBgn0030244 protein_coding_gene - - - CG2157 - CG2157 11-Aug-17 DroID_v2017_08 Drer\LOC100001051 - - - - - FBgn0001907 l(2)24De lethal (2) 24De http://flybase.org/reports/FBgn0001907 - gene - - - "jf3, l(2)jf3, l(2)24De" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265976 CR44755 - http://flybase.org/reports/FBgn0265976 non_protein_coding_gene - - - CR44755 - CR44755 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030740 CG9917 - http://flybase.org/reports/FBgn0030740 protein_coding_gene - - - "anon-WO0140519.229, CG9917" IPR009832:Protein of unknown function DUF1397 CG9917 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0028168 l(3)S027707 lethal (3) S027707 http://flybase.org/reports/FBgn0028168 gene - - - "0277/07, l(3)S027707" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265311 CR44284 - http://flybase.org/reports/FBgn0265311 non_protein_coding_gene - - - CR44284 - CR44284 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036680 Cpr73D Cuticular protein 73D http://flybase.org/reports/FBgn0036680 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model sleep ; GO:0030431 | inferred from expression pattern extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr73D, CG9665" IPR000618:Insect cuticle protein CG9665 11-Aug-17 DroID_v2017_08 - - "Cele\F34D10.6, Cele\mlt-2" - - - viable FBgn0053798 CG33798 - http://flybase.org/reports/FBgn0053798 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1039, CG33798" IPR010512:Protein of unknown function DUF1091 CG33798 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034479 CG8654 - http://flybase.org/reports/FBgn0034479 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 CG8654 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG8654 11-Aug-17 DroID_v2017_08 "Drer\sv2a, Drer\slc22a16, Drer\zgc:153639, Drer\slc22a7b.3, Drer\wdhd1, Drer\LOC566640, Drer\slc22a7b.2, Drer\svopa, Drer\slc22a17, Drer\slc22a7a, Drer\slc22a13, Drer\sv2c, Drer\zmp:0000001102, Drer\slc22a6l, Drer\slc22a7b.1, Drer\slc22a31, Drer\LOC100334012, Drer\si:dkey-166k12.1, Drer\oatx, Drer\slc22a23, Drer\slc22a15, Drer\si:dkey-119m7.4, Drer\sv2bb" "Scer\PHO84, Scer\GIT1, Scer\HXT5, Scer\HXT3" "Cele\ZK892.3, Cele\F32H5.4, Cele\K05F1.6, Cele\oct-2, Cele\pes-23, Cele\F17C11.10, Cele\oct-1, Cele\F23F12.13, Cele\Y66D12A.13, Cele\F17C11.12, Cele\T08B1.1, Cele\Y82E9BR.16, Cele\F23F12.3, Cele\B0252.3, Cele\Y57G11C.23, Cele\svop-1, Cele\C53B4.1, Cele\Y51A2D.18, Cele\T12B3.2, Cele\F45E10.2, Cele\C44C10.3" "Xtro\slc22a5, Xtro\sv2c, Xtro\sv2a, Xtro\slc22a6, Xtro\svop, Xtro\slc22a13, Xtro\sv2b" "Mmus\Slc22a22, Mmus\Sv2c, Mmus\Slc22a4, Mmus\Slc22a7, Mmus\Slc22a29, Mmus\Slc22a5, Mmus\Slc22a8, Mmus\Slc22a15, Mmus\Slc22a16, Mmus\Slc22a6, Mmus\Slc22a14, Mmus\Slc22a28, Mmus\Slc22a12, Mmus\Slc22a26, Mmus\Sv2b, Mmus\Slc22a30, Mmus\Slc22a20, Mmus\Sv2a, Mmus\Slc22a27, Mmus\Slc22a19, Mmus\Slc22a21, Mmus\Slc22a23, Mmus\Svop, Mmus\Slc22a17, Mmus\Slc22a13, Mmus\Wdhd1" "Hsap\SLC22A11, Hsap\SLC22A9, Hsap\SV2B, Hsap\SLC22A17, Hsap\SLC22A12, Hsap\SLC22A8, Hsap\SLC22A10, Hsap\SLC22A14, Hsap\SV2A, Hsap\SLC22A16, Hsap\SLC22A24, Hsap\SLC22A6, Hsap\SLC22A23, Hsap\SLC22A13, Hsap\SV2C, Hsap\SLC22A31, Hsap\SLC22A15, Hsap\SLC22A20, Hsap\SLC22A7, Hsap\SLC22A25, Hsap\SVOP, Hsap\SLC22A4, Hsap\SLC22A5" viable FBgn0266249 CR44944 - http://flybase.org/reports/FBgn0266249 non_protein_coding_gene - - - "CR44944, lincRNA.783" - CR44944 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002383 l(3)93Cc lethal (3) 93Cc http://flybase.org/reports/FBgn0002383 - gene - - - "er14, l(3)er14, l(3)93Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028740 CG6362 - http://flybase.org/reports/FBgn0028740 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "EG:52C10.6, CG6362" - CG6362 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0041612 X-element\ORF2 X-element ORF2 http://flybase.org/reports/FBgn0041612 transposable_element_gene RNA-directed DNA polymerase activity ; GO:0003964 | inferred from mutant phenotype "transposition, DNA-mediated ; GO:0006313 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available "X-element\ORF2, RT, ORF2" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043862 pf-4 pairing failure-4 http://flybase.org/reports/FBgn0043862 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG4, pf-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003912 Tyr3 Tyrosine 3 http://flybase.org/reports/FBgn0003912 - gene - - - "Tyr-3, Tyr3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085200 CG34171 - http://flybase.org/reports/FBgn0085200 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - CG34171 "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34171 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-78l4.4, Drer\LOC103908930, Drer\si:ch211-165b19.8, Drer\LOC558805" - - "Xtro\prss2, Xtro\prss1.2, Xtro\LOC496746" "Mmus\Cfd, Mmus\Klk1b5, Mmus\Klk8, Mmus\Gzma" "Hsap\KLK8, Hsap\CFD, Hsap\KLK10, Hsap\GZMK, Hsap\PRSS57, Hsap\AZU1" FBgn0000800 fs(1)de11 female sterile (1) defective eggs 11 http://flybase.org/reports/FBgn0000800 - gene - - - "de11, fs(1)de11" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "dorsal appendage,chorion" FBgn0040882 CG15045 - http://flybase.org/reports/FBgn0040882 protein_coding_gene - - - CG15045 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035344 Cyp4d20 Cyp4d20 http://flybase.org/reports/FBgn0035344 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4d20, CG16761, Cyp4d20, RH59895, CYP4d20" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG16761 11-Aug-17 DroID_v2017_08 "Drer\cyp3c4, Drer\cyp26c1, Drer\cyp3c3, Drer\cyp20a1, Drer\cyp46a1.3, Drer\LOC100329425, Drer\cyp4f3, Drer\cyp26b1, Drer\cyp19a1b, Drer\cyp46a1.2, Drer\cyp26a1, Drer\cyp46a1.1, Drer\cyp4v7, Drer\cyp4v8, Drer\cyp46a1.4, Drer\cyp3c2, Drer\cyp3a65, Drer\cyp19a1a, Drer\cyp3c1, Drer\cyp4t8" "Scer\ERG5, Scer\DIT2" "Cele\cyp-29A4, Cele\cyp-31A5, Cele\cyp-13A11, Cele\cyp-13A1, Cele\cyp-31A3, Cele\cyp-13A5, Cele\cyp-32A1, Cele\cyp-37A1, Cele\cyp-13A8, Cele\cyp-13A4, Cele\cyp-25A4, Cele\cyp-25A3, Cele\cyp-42A1, Cele\cyp-32B1, Cele\cyp-25A2, Cele\cyp-29A3, Cele\cyp-25A1, Cele\cyp-13A12, Cele\cyp-13A7, Cele\cyp-13A3, Cele\cyp-13A10, Cele\cyp-29A2, Cele\cyp-37B1, Cele\cyp-31A2" "Xtro\cyp26a1, Xtro\cyp26c1, Xtro\cyp4f2, Xtro\cyp4v2, Xtro\LOC100487918, Xtro\cyp26b1, Xtro\LOC100488227, Xtro\cyp4b1, Xtro\cyp4b1.2, Xtro\mgc108213, Xtro\cyp20a1, Xtro\cyp19a1, Xtro\cyp4f22" "Mmus\Cyp4a32, Mmus\Cyp3a57, Mmus\Cyp4v3, Mmus\Cyp4f18, Mmus\Cyp4f15, Mmus\Cyp3a41b, Mmus\Cyp4a12a, Mmus\Cyp4a14, Mmus\Cyp26c1, Mmus\Cyp4a31, Mmus\Cyp4f16, Mmus\Cyp20a1, Mmus\Cyp4a30b, Mmus\Cyp3a44, Mmus\Cyp4f37, Mmus\Cyp3a25, Mmus\Cyp3a13, Mmus\Cyp3a11, Mmus\Cyp4f39, Mmus\Cyp4f14, Mmus\Cyp26b1, Mmus\Cyp4f13, Mmus\Cyp4x1, Mmus\Cyp3a16, Mmus\Cyp4a29, Mmus\Cyp3a41a, Mmus\Cyp46a1, Mmus\Cyp4a10, Mmus\Cyp4f17, Mmus\Cyp19a1, Mmus\Cyp4b1, Mmus\Cyp4a12b, Mmus\Cyp3a59, Mmus\Cyp4f40, Mmus\Cyp26a1" "Hsap\CYP20A1, Hsap\CYP4V2, Hsap\CYP4X1, Hsap\CYP3A4, Hsap\CYP3A5, Hsap\CYP4F2, Hsap\CYP26C1, Hsap\CYP19A1, Hsap\CYP3A7, Hsap\CYP3A43, Hsap\CYP4F11, Hsap\CYP4Z1, Hsap\CYP4A11, Hsap\CYP46A1, Hsap\CYP4F22, Hsap\CYP4A22, Hsap\CYP4F3, Hsap\CYP26B1, Hsap\CYP4F8, Hsap\CYP4F12, Hsap\CYP4B1, Hsap\CYP26A1" viable FBgn0260789 mxc multi sex combs http://flybase.org/reports/FBgn0260789 protein_coding_gene - hemocyte differentiation ; GO:0042386 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype hemopoiesis ; GO:0030097 | traceable author statement hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype histone locus body ; GO:0035363 | inferred from direct assay "mxc, MXC, CG12124, l(1)mbn, CG12058, Mxc, dNPAT, NPAT, MPM2, MPM-2" IPR006594:LIS1 homology motif CG12124 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027785 NP15.6 NP15.6 http://flybase.org/reports/FBgn0027785 FBgn0062121 protein_coding_gene molecular_function ; GO:0003674 | no biological data available respiratory electron transport chain ; GO:0022904 | inferred from sequence or structural similarity with HGNC:20372 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with HGNC:20372 "CG6008, anon-WO0118547.281, NP15.6" "IPR019329:NADH:ubiquinone oxidoreductase, ESSS subunit" CG6008 11-Aug-17 DroID_v2017_08 Drer\ndufb11 - Cele\F42G8.10 - "Mmus\1700029P11Rik, Mmus\Ndufb11" Hsap\NDUFB11 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0026242 fuzzy-cellularization fuzzy cellularization http://flybase.org/reports/FBgn0026242 - gene - - - fuzzy-cellularization - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030869 Socs16D Suppressor of Cytokine Signaling at 16D http://flybase.org/reports/FBgn0030869 protein_coding_gene protein kinase inhibitor activity ; GO:0004860 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A regulation of growth ; GO:0040008 | inferred from electronic annotation with InterPro:IPR028421 negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 TORC1 signaling ; GO:0038202 | inferred from mutant phenotype negative regulation of protein kinase activity ; GO:0006469 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 cytokine-mediated signaling pathway ; GO:0019221 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 "dmSocs16D, SOCS, SOCS16D, Socs16E, socs16D, CG8146, Socs16D, Socs 16D" "IPR000980:SH2 domain, IPR001496:SOCS box domain, IPR028421:Suppressor of cytokine signalling 6" CG8146 11-Aug-17 DroID_v2017_08 "Drer\socs9, Drer\cish, Drer\socs1b, Drer\socs2, Drer\socs1a, Drer\socs7, Drer\socs3a, Drer\socs5a, Drer\socs6, Drer\socs4, Drer\socs6b, Drer\socs3b, Drer\cishb" - Cele\F39B2.5 "Xtro\socs6, Xtro\socs3, Xtro\socs4, Xtro\socs7, Xtro\socs2, Xtro\cish, Xtro\socs1, Xtro\socs3, Xtro\socs5" "Mmus\Socs5, Mmus\Socs6, Mmus\Socs4, Mmus\Socs3, Mmus\Socs1, Mmus\Socs7, Mmus\Cish, Mmus\Socs2" "Hsap\SOCS1, Hsap\SOCS6, Hsap\SOCS5, Hsap\SOCS2, Hsap\SOCS3, Hsap\SOCS7, Hsap\SOCS4, Hsap\CISH" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0025369 Hemagglutinin Hemagglutinin http://flybase.org/reports/FBgn0025369 - gene - - - Hemagglutinin - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002277 l(3)73Ab lethal (3) 73Ab http://flybase.org/reports/FBgn0002277 - gene - - - "l(3)std37, l(3)133.37, l(3)133.10, l(3)73Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" FBgn0086660 snoRNA:Psi28S-1837a snoRNA:Psi28S-1837a http://flybase.org/reports/FBgn0086660 snoRNA_gene - - - "snoRNA:11, psi28S-1837a, Dm-14, snoR14, CR33652, snoRNA:14, Psi 28S-1837a(SnoR14), Psi28S-1837a, snoRNA:Psi28S-1837a" - CR33652 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046336 da::twi da::twi http://flybase.org/reports/FBgn0046336 engineered_fusion_gene - - - "da::twi, Twi-Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic somatic muscle,embryonic/larval visceral muscle,presumptive embryonic salivary gland" FBgn0003225 rea rearranged tergites http://flybase.org/reports/FBgn0003225 - gene - - - rea - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,reduced,fertile" tergite FBgn0003627 Su(var)316 Suppressor of variegation 316 http://flybase.org/reports/FBgn0003627 - gene - - - "Su(var)3-316, Su-var(3)316, Su(var)316, 316" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0039668 Trc8 TRC8 ring finger protein http://flybase.org/reports/FBgn0039668 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:17023 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V3C1 inferred from physical interaction with UniProtKB:Q9XZ58 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 negative regulation of growth ; GO:0045926 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 ventral midline development ; GO:0007418 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:17023 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "DTrc8, CG2304, TRC8, Dtrc8, Trc8" "IPR025754:TRC8 N-terminal domain, IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2304 11-Aug-17 DroID_v2017_08 "Drer\rnf145a, Drer\amfr, Drer\rnf145b, Drer\chfr, Drer\zmp:0000000662, Drer\syvn1, Drer\rnf139" "Scer\SAN1, Scer\HRD1" "Cele\Y119C1B.5, Cele\sel-11" "Xtro\syvn1, Xtro\rnf139, Xtro\chfr, Xtro\rnft2, Xtro\amfr, Xtro\rnf145, Xtro\LOC100127651" "Mmus\Rnf145, Mmus\Chfr, Mmus\Syvn1, Mmus\Rnft2, Mmus\Amfr, Mmus\Rnf139" "Hsap\RNFT2, Hsap\RNF139, Hsap\SYVN1, Hsap\CHFR, Hsap\AMFR, Hsap\RNF145, Hsap\RNFT1" "size defective,lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable" "wing,eye" FBgn0003937 snRNA:U5:39B small nuclear RNA U5 at 39B http://flybase.org/reports/FBgn0003937 FBgn0003932 snRNA_gene - - - "U5, snRNA[[3]], K2, dU5, snRNA4, snRNA3, U5snRNA39B, U5snRNA, snRNA:U5, snRNA:U5:39B, U5 snRNA 39B, U5 snRNA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038751 CG4770 - http://flybase.org/reports/FBgn0038751 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - CG4770 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG4770 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" - Cele\fard-1 Xtro\far1 "Mmus\Far1, Mmus\Far2" "Hsap\FAR2, Hsap\FAR1" viable FBgn0027649 l(2)CL-L lethal (2) Cell Lethal Left http://flybase.org/reports/FBgn0027649 - gene - - - "CL2L, l(2)CL-L" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051910 CG31910 - http://flybase.org/reports/FBgn0051910 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs09e03, BcDNA:AT21561, CG31910" - CG31910 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC00946 E -0.084424284 -0.541682233 -1.724448191 0.300547712 0.063334014 -1.272003118 FBgn0035171 CG12502 - http://flybase.org/reports/FBgn0035171 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12502 "IPR018787:Protein of unknown function DUF2371, TMEM200" CG12502 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-204a13.2, Drer\tmem200c, Drer\tmem200a, Drer\LOC101883651" - Cele\R05D7.3 "Xtro\tmem200a, Xtro\tmem200c" "Mmus\Tmem200a, Mmus\Tmem200c, Mmus\Tmem200b" "Hsap\TMEM200C, Hsap\TMEM200B, Hsap\TMEM200A" viable FBgn0037857 Tengl4 Testis EndoG-Like 4 http://flybase.org/reports/FBgn0037857 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - "CG4683, Tengl4" "IPR001604:DNA/RNA non-specific endonuclease, IPR020821:Extracellular Endonuclease, subunit A" CG4683 11-Aug-17 DroID_v2017_08 "Drer\LOC100333474, Drer\LOC103910196, Drer\endog" Scer\NUC1 Cele\cps-6 "Xtro\exog, Xtro\endog" "Mmus\Endog, Mmus\Exog" "Hsap\EXOG, Hsap\ENDOG" "viable,fertile" FBgn0004759 l(3)89Bl lethal (3) 89Bl http://flybase.org/reports/FBgn0004759 - gene - - - l(3)89Bl - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267484 CR45834 - http://flybase.org/reports/FBgn0267484 non_protein_coding_gene - - - CR45834 - CR45834 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000941 fs(2)A11 female sterile (2) A11 http://flybase.org/reports/FBgn0000941 - gene - - - fs(2)A11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" "female reproductive system,maternal effect" FBgn0038737 CG11447 - http://flybase.org/reports/FBgn0038737 protein_coding_gene "methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR002877, InterPro:IPR015507" RNA methylation ; GO:0001510 | inferred from electronic annotation with InterPro:IPR015507 - CG11447 "IPR002877:Ribosomal RNA methyltransferase FtsJ domain, IPR015507:Ribosomal RNA large subunit methyltransferase E, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG11447 11-Aug-17 DroID_v2017_08 "Drer\ftsj3, Drer\ftsj2" "Scer\SPB1, Scer\MRM2" "Cele\H06I04.3, Cele\F45G2.9" Xtro\ftsj2 "Mmus\Mrm2, Mmus\Ftsj3" "Hsap\MRM2, Hsap\FTSJ3" viable DRSC27849 K -0.849467673 -0.254383549 -0.879631263 0.549433847 -2.00294258 0.074928742 FBgn0284257 Ttd14 TRPL translocation defect 14 http://flybase.org/reports/FBgn0284257 protein_coding_gene - cellular response to light stimulus ; GO:0071482 | inferred from mutant phenotype positive regulation of intracellular protein transport ; GO:0090316 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG30118, ttd14, Ttd14, CG16859, CG5544, l(2)k04808, l(2)08770" "IPR033469:CYTH-like domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG30118 11-Aug-17 DroID_v2017_08 - - Cele\unc-132 - - - "lethal,recessive,partially lethal - majority die" "crystal cell,plasmatocyte" FBgn0031729 CG12511 - http://flybase.org/reports/FBgn0031729 protein_coding_gene - mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000482219 integral component of mitochondrial outer membrane ; GO:0031307 | inferred from biological aspect of ancestor with PANTHER:PTN000482219 CG12511 IPR007014:FUN14 CG12511 11-Aug-17 DroID_v2017_08 "Drer\fundc2, Drer\fundc1" Scer\FUN14 Cele\T06D8.7 Xtro\fundc1 "Mmus\Fundc2, Mmus\Fundc1" "Hsap\FUNDC2, Hsap\FUNDC1" viable FBgn0044407 Scim20 Sensitized chromosome inheritance modifier 20 http://flybase.org/reports/FBgn0044407 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0030764 CG9777 - http://flybase.org/reports/FBgn0030764 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9777 - CG9777 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000150 awd abnormal wing discs http://flybase.org/reports/FBgn0000150 "FBgn0011322, FBgn0024573, FBgn0025960, FBgn0046351, FBgn0046352, FBgn0062949, FBgn0064938" protein_coding_gene nucleoside diphosphate kinase activity ; GO:0004550 | inferred from direct assay inferred from mutant phenotype ATP binding ; GO:0005524 | inferred from direct assay magnesium ion binding ; GO:0000287 | inferred from direct assay nucleoside diphosphate kinase activity ; GO:0004550 | inferred from sequence or structural similarity with EMBL:J05207 inferred from direct assay inferred from mutant phenotype kinase activity ; GO:0016301 | inferred from direct assay GTP binding ; GO:0005525 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from direct assay nucleoside diphosphate kinase activity ; GO:0004550 | inferred from direct assay "CTP biosynthetic process ; GO:0006241 | inferred from electronic annotation with InterPro:IPR001564 UTP biosynthetic process ; GO:0006228 | inferred from electronic annotation with InterPro:IPR001564 GTP biosynthetic process ; GO:0006183 | inferred from electronic annotation with InterPro:IPR001564 protein autophosphorylation ; GO:0046777 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from direct assay GTP biosynthetic process ; GO:0006183 | traceable author statement adherens junction organization ; GO:0034332 | inferred from mutant phenotype regulation of tube architecture, open tracheal system ; GO:0035152 | inferred from mutant phenotype UTP biosynthetic process ; GO:0006228 | traceable author statement CTP biosynthetic process ; GO:0006241 | traceable author statement open tracheal system development ; GO:0007424 | inferred from expression pattern inferred from mutant phenotype nucleoside diphosphate phosphorylation ; GO:0006165 | inferred from sequence or structural similarity with EMBL:J05207 inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype nucleotide metabolic process ; GO:0009117 | traceable author statement establishment or maintenance of polarity of follicular epithelium ; GO:0016334 | inferred from mutant phenotype" microtubule associated complex ; GO:0005875 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay nuclear microtubule ; GO:0005880 | inferred from mutant phenotype "awd, Kpn, K-pn, CG2210, NDPK, e(shi)A, eshiA, clone 2.27, clone 2.28, NDKB, 1084/08, l(3)j2A4, l(3)L8700, anon-EST:Liang-2.28, anon-EST:Liang-2.27, BcDNA:RH27794, BcDNA:GM19775, anon-WO0172774.82, anon-WO0172774.80, Awd, Nm23/awd, Nm23" "IPR001564:Nucleoside diphosphate kinase, IPR023005:Nucleoside diphosphate kinase, active site" CG2210 11-Aug-17 DroID_v2017_08 "Drer\nme2b.1, Drer\nme2b.2, Drer\nme7, Drer\nme2a, Drer\nme3, Drer\nme5, Drer\nme6, Drer\LOC100538266, Drer\si:ch1073-205c8.3, Drer\nme4" Scer\YNK1 Cele\ndk-1 "Xtro\nme4, Xtro\nme2, Xtro\nme9, Xtro\nme5, Xtro\nme6, Xtro\nme7, Xtro\nme3" "Mmus\Nme8, Mmus\Nme2, Mmus\Nme1, Mmus\Nme3, Mmus\Nme4, Mmus\Nme7, Mmus\Nme5, Mmus\Nme6" "Hsap\NME4, Hsap\NME5, Hsap\NME3, Hsap\NME8, Hsap\DECR2, Hsap\NME6, Hsap\NME1-NME2, Hsap\NME1, Hsap\NME7, Hsap\NME2" " embryonic stage -- adult stage , larval stage | third instar , larval stage | second instar " dorsal mesothoracic disc | restricted

" embryonic stage -- adult stage , larval stage | third instar " dorsal mesothoracic disc

"lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,viable,wild-type,lethal - all die before end of P-stage,some die during pharate adult stage,paralytic,heat sensitive" "egg chamber,heat sensitive,follicle cell,presumptive embryonic/larval tracheal system,dorsal group branch precursor,embryonic dorsal group branch & filopodium,somatic clone,dorsal trunk primordium,embryonic/larval tracheal system,embryonic/larval dorsal trunk,photoreceptor cell,optic cartridge" DRSC16906 I 1.536600582 -0.270013002 -0.802434165 0.352023911 0.873164603 -0.958697643 FBgn0053093 CG33093 - http://flybase.org/reports/FBgn0053093 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005123 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 - "CG5340, CG33093" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR027443:Isopenicillin N synthase-like, IPR026992:Non-haem dioxygenase N-terminal domain" CG33093 11-Aug-17 DroID_v2017_08 Drer\si:dkey-10o6.2 - - - - - viable FBgn0013230 E(var)1817 E(var)1817 http://flybase.org/reports/FBgn0013230 - gene - - - E(var)1817 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0053966 CG33966 - http://flybase.org/reports/FBgn0053966 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "CG1211, CG33966" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG33966 11-Aug-17 DroID_v2017_08 "Drer\rlbp1a, Drer\sec14l7, Drer\ttpa, Drer\rlbp1b, Drer\clvs2, Drer\sec14l8, Drer\ttpal" "Scer\SFH5, Scer\YKL091C, Scer\SEC14" - "Xtro\clvs1, Xtro\sec14l3, Xtro\mospd2, Xtro\sec14l1, Xtro\sec14l5, Xtro\clvs2, Xtro\rlbp1, Xtro\ttpa, Xtro\ttpal" "Mmus\Ttpal, Mmus\Sec14l1, Mmus\Ttpa, Mmus\Sec14l3, Mmus\Sec14l4, Mmus\Sec14l2, Mmus\Clvs1, Mmus\Rlbp1, Mmus\Clvs2, Mmus\Sec14l5" "Hsap\SEC14L6, Hsap\TTPAL, Hsap\SEC14L4, Hsap\SEC14L1, Hsap\SEC14L3, Hsap\CLVS1, Hsap\SEC14L2, Hsap\RLBP1, Hsap\SEC14L5, Hsap\TTPA, Hsap\CLVS2" viable FBgn0061475 18SrRNA 18SrRNA http://flybase.org/reports/FBgn0061475 rRNA_gene - - - "18S rRNA, 18s rRNA, 18S, 18S RNA, 18S rDNA, NEST:bs01c01, BEST:SD07466, BEST:LP07011, BEST:LD33742, BEST:LD10585, BEST:GH15369, BEST:GH11893, 18SRNA, 18SrRNA, 18 S rRNA, CR40959" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0003618 Su(var)2-37 Suppressor of variegation 2-37 http://flybase.org/reports/FBgn0003618 - gene - - - Su(var)2-37 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082365 EP3683 EP3683 http://flybase.org/reports/FBgn0082365 gene - - - EP3683 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0033658 Twdlbeta Tweedlebeta http://flybase.org/reports/FBgn0033658 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "CT25838, CG8986, TwdlBeta, Twdlbeta" IPR004145:Domain of unknown function DUF243 CG8986 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031235 CG13693 - http://flybase.org/reports/FBgn0031235 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13693 IPR025254:Domain of unknown function DUF4201 CG13693 11-Aug-17 DroID_v2017_08 "Drer\ccdc113, Drer\ccdc96" - - Xtro\ccdc113 "Mmus\Ccdc96, Mmus\Ccdc113" "Hsap\CCDC96, Hsap\CCDC113" viable FBgn0034485 CG11099 - http://flybase.org/reports/FBgn0034485 protein_coding_gene - - - "CT31033, CG11099" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG11099 11-Aug-17 DroID_v2017_08 "Drer\lrrc18b, Drer\lrsam1, Drer\lrrc28, Drer\lrrc18a" - - "Xtro\lrrc69, Xtro\lrrc18, Xtro\lrsam1" "Mmus\Lrsam1, Mmus\Lrrc18, Mmus\Lrrc28" "Hsap\LRSAM1, Hsap\LRRC18, Hsap\LRRC28" viable FBgn0017392 l(1)15Bb lethal (1) 15Bb http://flybase.org/reports/FBgn0017392 - gene - - - l(1)15Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262649 l(2)47A7 lethal (2) 47A7 http://flybase.org/reports/FBgn0262649 gene - - - l(2)47A7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010355 Taf1 TBP-associated factor 1 http://flybase.org/reports/FBgn0010355 "FBgn0004775, FBgn0010420, FBgn0016735" protein_coding_gene "TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000356981 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription regulatory region DNA binding ; GO:0044212 | contributes_to inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf12 inferred from physical interaction with Taf11 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:11535 histone acetyltransferase activity (H3-K14 specific) ; GO:0036408 | inferred from direct assay RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly ; GO:0001129 | inferred from physical interaction with Tbp H4 histone acetyltransferase activity ; GO:0010485 | inferred from direct assay" "neurogenesis ; GO:0022008 | inferred from mutant phenotype RNA polymerase II transcriptional preinitiation complex assembly ; GO:0051123 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:11535 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay histone H4 acetylation ; GO:0043967 | inferred from direct assay positive regulation of transcription initiation from RNA polymerase II promoter ; GO:0060261 | inferred from direct assay histone H3-K14 acetylation ; GO:0044154 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11535 inferred from sequence or structural similarity with SGD:S000001039 DNA-templated transcription, initiation ; GO:0006352 | inferred from direct assay positive regulation of transcription of Notch receptor target ; GO:0007221 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype" transcription factor TFIID complex ; GO:0005669 | inferred from physical interaction with Taf4 inferred from physical interaction with Taf6 nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11535 inferred from sequence or structural similarity with SGD:S000001039 nucleolus ; GO:0005730 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "dTAF[[II]]230, TAF[[II]]230, dmTAF1, dTAF[[II]]250, TAF250/230, TAF, TFIID, TAF250, dmTAF[[II]]230, TAF[[II]], TAF[[II]]250, TAF[II]250, TAF1, dTAFII250, dTAF230, TAFII250, TFIID TAF250, d230, TAFII-250, CG17603, SR3-5, Taf250, TAF[[II]]250/230, dTAF250, TAF230, cell, p230, Taf230, Taf[[II]]250, l(3)84Ab, TAF200, cel, EfW1, Taf200, BG:DS00004.13, Taf1, Taf1p, dTAF1" "IPR017956:AT hook, DNA-binding motif, IPR018359:Bromodomain, conserved site, IPR001487:Bromodomain, IPR009067:TAFII-230 TBP-binding, IPR011177:Transcription initiation factor TFIID subunit 1, animal, IPR022591:Transcription initiation factor TFIID subunit 1, domain of unknown function" CG17603 11-Aug-17 DroID_v2017_08 Drer\taf1 Scer\TAF1 Cele\taf-1 Xtro\taf1 Mmus\Taf1 "Hsap\TAF1, Hsap\TAF1L" "viable,lethal,recessive,partially lethal - majority die,female sterile,lethal - all die before end of larval stage,cell autonomous,some die during larval stage,neuroanatomy defective,visible,some die during pupal stage" "ocellus,oocyte,interommatidial bristle,eye photoreceptor cell,macrochaeta,microchaeta,male terminalia,wing vein L4,wing,ovary,egg chamber,second instar larva,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC12607 IK -2.129191124 0.841473644 -1.452006797 -0.506402004 2.130553819 2.755929324 FBgn0264598 PsGEF Protostome-specific GEF http://flybase.org/reports/FBgn0264598 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from electronic annotation with InterPro:IPR000219 Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence model calcium-dependent phospholipid binding ; GO:0005544 | inferred from sequence model regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 mushroom body development ; GO:0016319 | inferred from genetic interaction with Rac1 positive regulation of ruffle assembly ; GO:1900029 | inferred from direct assay positive regulation of Rac protein signal transduction ; GO:0035022 | inferred from direct assay regulation of actin filament polymerization ; GO:0030833 | inferred from direct assay intracellular ; GO:0005622 | inferred from direct assay "PsGEF, PsGef, null, FBgn0264598, CG43947, CG14045, EG:BACH7M4.1, EG:BACH7M4.2, DmPsGEF, CG14047, EG:BACH48C10.4" "IPR011993:PH domain-like, IPR000219:Dbl homology (DH) domain, IPR001478:PDZ domain, IPR000008:C2 domain, IPR032057:Protein of unknown function DUF4799" CG43947 11-Aug-17 DroID_v2017_08 "Drer\inadl, Drer\dlg5a, Drer\arhgef10lb, Drer\rph3aa, Drer\grip1, Drer\rph3ab, Drer\pard3bb, Drer\grip2b, Drer\pdzd7b, Drer\doc2d, Drer\grid2ipa, Drer\si:dkey-92i15.4, Drer\slc9a3r1, Drer\si:dkey-93n13.3, Drer\arhgef10la, Drer\lnx1, Drer\il16, Drer\arhgef10" - - "Xtro\grip2, Xtro\LOC100493255, Xtro\arhgef10l, Xtro\lnx1, Xtro\dlg5, Xtro\grip1, Xtro\rph3a, Xtro\grid2ip" "Mmus\Pdzd11, Mmus\Lnx1, Mmus\Pdzph1, Mmus\Arhgef10l, Mmus\Patj, Mmus\Il16, Mmus\Grip1, Mmus\Arhgef10, Mmus\Doc2g, Mmus\Mpdz, Mmus\Doc2b, Mmus\Grip2, Mmus\Ush1c, Mmus\Pdzd2, Mmus\Dlg5, Mmus\Grid2ip, Mmus\Rph3al, Mmus\Rph3a, Mmus\Grasp" "Hsap\GRID2IP, Hsap\USH1C, Hsap\MPDZ, Hsap\IL16, Hsap\GRASP, Hsap\PATJ, Hsap\ARHGEF10L, Hsap\RPH3A, Hsap\LNX1, Hsap\DLG5, Hsap\DOC2B, Hsap\PDZD2, Hsap\FRMPD2, Hsap\GRIP1, Hsap\ARHGEF10, Hsap\RPH3AL, Hsap\PARD3B" DRSC18596 E 0.906126963 0.259884469 2.935523645 0.712665742 -1.139385265 -0.177717615 FBgn0039730 CG7903 - http://flybase.org/reports/FBgn0039730 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg7903, CG7903" IPR000504:RNA recognition motif domain CG7903 11-Aug-17 DroID_v2017_08 "Drer\adkb, Drer\rbm4.1, Drer\rbm14b, Drer\zgc:77262, Drer\rbm4.3, Drer\rbm14a, Drer\adka, Drer\rbm4.2" - "Cele\rnp-1, Cele\R07H5.8" "Xtro\rbm14, Xtro\adk, Xtro\rbm4b" "Mmus\Adk, Mmus\Rbm14, Mmus\Rbm4, Mmus\Rbm4b" "Hsap\RBM4, Hsap\ADK, Hsap\RBM14" FBgn0000264 Cubl Curled blistered http://flybase.org/reports/FBgn0000264 - gene - - - "Cubl, Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0061084 l(3)S012225a lethal (3) S012225a http://flybase.org/reports/FBgn0061084 gene - - - "0122/25, l(3)S012225a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0260305 GSd315 - http://flybase.org/reports/FBgn0260305 gene - - - GSd315 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,bouton" FBgn0259853 Su(Ste):CR42422 Su(Ste):CR42422 http://flybase.org/reports/FBgn0259853 non_protein_coding_gene - - - "Su(Ste):CR42422, RR41835, CR42422" - CR42422 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001497 l(1)10Bk lethal (1) 10Bk http://flybase.org/reports/FBgn0001497 - gene - - - "10Bk, 3, l(1)10Bk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,polyphasic,germline clone,maternal effect" FBgn0029525 CG18273 - http://flybase.org/reports/FBgn0029525 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "EG:171D11.6, CG13372, CG18273" "IPR018849:Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal" CG18273 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0039522 CG13972 - http://flybase.org/reports/FBgn0039522 protein_coding_gene - - - CG13972 "IPR000048:IQ motif, EF-hand binding site" CG13972 11-Aug-17 DroID_v2017_08 Drer\iqcg - - - "Mmus\Iqcf3, Mmus\Iqcg" Hsap\IQCG viable FBgn0066129 E(sda)D E(sda)D http://flybase.org/reports/FBgn0066129 gene molecular_function ; GO:0003674 | no biological data available mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E(sda)D, Line D" - - 11-Aug-17 DroID_v2017_08 - - - - - - bang sensitive FBgn0262233 mir-2494 mir-2494 stem loop http://flybase.org/reports/FBgn0262233 miRNA_gene - - - "mir-2494, dme-mir-2494, CR42940, dme-miR-2494-5p, miR-2494" - CR42940 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032836 CG10680 - http://flybase.org/reports/FBgn0032836 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10680 - CG10680 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039678 Obp99a Odorant-binding protein 99a http://flybase.org/reports/FBgn0039678 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush response to pheromone ; GO:0019236 | inferred from sequence or structural similarity with UniProtKB:O02372 olfactory behavior ; GO:0042048 | inferred from sequence or structural similarity with UniProtKB:O02372 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:O02372 extracellular region ; GO:0005576 | inferred from sequence model endomembrane system ; GO:0012505 | inferred from direct assay "CG18111, 99a, OBP99a, BcDNA:RH70762, Obp99a, DmelObp99a" IPR006170:Pheromone/general odorant binding protein CG18111 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035010 CG13579 - http://flybase.org/reports/FBgn0035010 protein_coding_gene G-protein coupled peptide receptor activity ; GO:0008528 | inferred from biological aspect of ancestor with PANTHER:PTN000660491 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity phospholipase C-activating G-protein coupled receptor signaling pathway ; GO:0007200 | inferred from biological aspect of ancestor with PANTHER:PTN000660491 neuropeptide signaling pathway ; GO:0007218 | inferred from biological aspect of ancestor with PANTHER:PTN000660491 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000660491 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "anon-WO0170980.152, anon-WO0170980.151, CG13579" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG13579 11-Aug-17 DroID_v2017_08 "Drer\ltb4r2a, Drer\kiss1rb, Drer\rxfp3, Drer\si:dkey-165n16.5, Drer\si:dkey-148a17.5, Drer\galr1a, Drer\cysltr1, Drer\ltb4r2b, Drer\si:dkey-33c3.1, Drer\htr1b, Drer\htr1fb, Drer\cysltr2a, Drer\htr1aa, Drer\gpr84, Drer\htr1ab, Drer\cysltr2b, Drer\kiss1ra, Drer\rxfp3.2b, Drer\si:ch73-379f7.4, Drer\galr2b, Drer\si:dkey-27n14.1, Drer\rxfp3.2a, Drer\uts2r, Drer\ltb4r, Drer\galr1b" - "Cele\npr-27, Cele\npr-14, Cele\ser-4" Xtro\cbwd1.1 "Mmus\Galr3, Mmus\Olfr685, Mmus\Galr2, Mmus\Ltb4r2, Mmus\Cysltr2, Mmus\Uts2r, Mmus\Rxfp4, Mmus\Gpr84, Mmus\Ltb4r1, Mmus\Galr1, Mmus\Cysltr1, Mmus\Rxfp3, Mmus\Kiss1r" "Hsap\GPR21, Hsap\CYSLTR2, Hsap\GPR52, Hsap\LTB4R2, Hsap\GPR84, Hsap\RXFP4, Hsap\GALR2, Hsap\HTR1D, Hsap\GALR1, Hsap\OR52L1, Hsap\MCHR2, Hsap\CYSLTR1, Hsap\GALR3, Hsap\RXFP3, Hsap\UTS2R, Hsap\KISS1R, Hsap\LTB4R" "viable,fertile,oxidative stress response defective,visible" trichogen cell FBgn0040077 primo-1 primo-1 http://flybase.org/reports/FBgn0040077 protein_coding_gene non-membrane spanning protein tyrosine phosphatase activity ; GO:0004726 | inferred from electronic annotation with InterPro:IPR002115 acid phosphatase activity ; GO:0003993 | inferred from electronic annotation with InterPro:IPR002115 protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with RGD:2020 inferred from sequence or structural similarity with SGD:S000006277 protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from sequence model protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000006277 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000006277 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000006277 cytoplasm ; GO:0005737 | non-traceable author statement "LMW-PTP, CG9599, primo, CG31311, CG33748, primo-1, Primo-1, BEO2" "IPR002115:Protein-tyrosine phosphatase, low molecular weight, mammalian, IPR017867:Protein-tyrosine phosphatase, low molecular weight, IPR023485:Phosphotyrosine protein phosphatase I superfamily" CG33748 11-Aug-17 DroID_v2017_08 Drer\acp1 Scer\LTP1 Cele\Y94H6A.7 Xtro\acp1 Mmus\Acp1 Hsap\ACP1 " pupal stage | stage P8 , pupal stage , larval stage , pupal stage | stage P6 , adult stage " " primary pigment cell

, cone cell

" "viable,fertile" FBgn0262314 mir-978 mir-978 stem loop http://flybase.org/reports/FBgn0262314 miRNA_gene - - - "dme-mir-978, mir-978, CR43021, miR-978" - CR43021 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing FBgn0028543 NimB2 Nimrod B2 http://flybase.org/reports/FBgn0028543 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mesoderm development ; GO:0007498 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with UniProtKB:Q1HAY7 extracellular region ; GO:0005576 | inferred from sequence model "CG31839, CG16882, CT37470, DS00180.7, BG:DS00180.7, NimB2, nimB2" "IPR009030:Growth factor receptor cysteine-rich domain, IPR000742:EGF-like domain, IPR003341:Cysteine rich repeat, tripleX" CG31839 11-Aug-17 DroID_v2017_08 "Drer\fgl2b, Drer\angptl3, Drer\zmp:0000000846, Drer\angpt4, Drer\zgc:158328, Drer\angptl5, Drer\LOC100007488, Drer\si:zfos-2330d3.8, Drer\tnxba, Drer\tnr, Drer\si:ch211-203k16.3, Drer\si:ch211-287a12.9, Drer\scarf1, Drer\si:zfos-2330d3.1, Drer\ccbe1, Drer\megf6a, Drer\fibcd1, Drer\tnc, Drer\creld2, Drer\fgb, Drer\esm1, Drer\angptl1a, Drer\si:zfos-2330d3.3, Drer\tnw, Drer\tnfaip6, Drer\dkk2, Drer\megf6b, Drer\megf11, Drer\si:zfos-2330d3.6, Drer\si:ch1073-110a20.3, Drer\si:ch211-157b11.8, Drer\angptl4, Drer\angptl2a, Drer\megf10, Drer\si:ch1073-110a20.1, Drer\zgc:194887, Drer\wu:fj11g02, Drer\angpt1, Drer\fgl2a, Drer\si:ch1073-110a20.2, Drer\zgc:171687, Drer\pear1, Drer\angpt2b, Drer\fgg, Drer\angptl2b, Drer\dkk1a, Drer\fga, Drer\angptl6" - "Cele\swm-1, Cele\ensh-1, Cele\T15B7.1, Cele\Y69H2.10, Cele\C08G9.2, Cele\K10D3.4, Cele\ZC504.1, Cele\abu-14, Cele\B0393.5, Cele\B0238.12, Cele\C25E10.8, Cele\C25E10.7, Cele\Y26D4A.12, Cele\W05B2.2, Cele\ZK1193.3, Cele\Y43C5A.2, Cele\R09H10.5, Cele\Y34B4A.5, Cele\C25E10.10, Cele\Y69H2.3" "Xtro\fibcd1, Xtro\tnn, Xtro\angpt1, Xtro\fcn3, Xtro\LOC100497330, Xtro\fgl1, Xtro\LOC100491105, Xtro\angptl4, Xtro\angpt4, Xtro\mfap4, Xtro\tnxb, Xtro\fgb, Xtro\fgl2, Xtro\tnfaip6, Xtro\angptl5, Xtro\stab2, Xtro\fcn2, Xtro\angptl3, Xtro\fcn1, Xtro\fgg, Xtro\megf11, Xtro\angptl2, Xtro\LOC100488177, Xtro\tnc, Xtro\fga, Xtro\tnr" "Mmus\Angptl1, Mmus\Dkk2, Mmus\Angpt4, Mmus\Fcnb, Mmus\Tnfaip6, Mmus\Angpt1, Mmus\Angptl7, Mmus\Fgl2, Mmus\Megf10, Mmus\Megf11, Mmus\Tnn, Mmus\Fgb, Mmus\Egfem1, Mmus\Stab1, Mmus\Tnc, Mmus\Angptl2, Mmus\Creld2, Mmus\Dkk3, Mmus\Fgg, Mmus\Fgl1, Mmus\Tnr, Mmus\Angptl4, Mmus\Angptl3, Mmus\Scarf1, Mmus\Fga, Mmus\Fcna, Mmus\Angptl6, Mmus\Fibcd1, Mmus\Tnxb, Mmus\Angpt2, Mmus\Pear1, Mmus\Esm1, Mmus\Megf6, Mmus\Mfap4" "Hsap\FCN3, Hsap\ANGPTL3, Hsap\FGL2, Hsap\ANGPTL6, Hsap\TNC, Hsap\FGA, Hsap\SCARF2, Hsap\TNXB, Hsap\ANGPT4, Hsap\ANGPTL1, Hsap\ANGPT1, Hsap\MEGF10, Hsap\FGB, Hsap\TNR, Hsap\FCN2, Hsap\ANGPTL2, Hsap\FGG, Hsap\PEAR1, Hsap\DKK2, Hsap\MEGF11, Hsap\TNN, Hsap\SCARF1, Hsap\ANGPTL7, Hsap\MEGF6, Hsap\ANGPTL4, Hsap\TNFAIP6, Hsap\FGL1, Hsap\ANGPTL5, Hsap\ANGPT2, Hsap\FIBCD1" viable FBgn0261089 Sytalpha Synaptotagmin alpha http://flybase.org/reports/FBgn0261089 protein_coding_gene clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium-dependent phospholipid binding ; GO:0005544 | non-traceable author statement calcium-dependent phospholipid binding ; GO:0005544 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 regulation of calcium ion-dependent exocytosis ; GO:0017158 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 vesicle-mediated transport ; GO:0016192 | non-traceable author statement vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 neurotransmitter secretion ; GO:0007269 | non-traceable author statement calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay "CG5559, sytalpha, dsytalpha, Syt alpha, Sytalpha, SYT3, Syt3, SYT-alpha" IPR000008:C2 domain CG5559 11-Aug-17 DroID_v2017_08 "Drer\syt5b, Drer\pla2g4f.2, Drer\syt1b, Drer\syt9b, Drer\sytl1, Drer\syt6b, Drer\syt5a, Drer\syt11a, Drer\syt9a, Drer\syt10, Drer\syt2a, Drer\syt17, Drer\syt6a, Drer\syt4, Drer\sytl2a, Drer\syt15, Drer\pla2g4f.1, Drer\syt3, Drer\si:ch211-266g18.6, Drer\sytl5, Drer\syt11b" - "Cele\snt-6, Cele\snt-7, Cele\DH11.5, Cele\snt-5" "Xtro\syt3, Xtro\syt6, Xtro\syt4, Xtro\pla2g4f, Xtro\jmjd7-pla2g4b" "Mmus\Sytl2, Mmus\Tc2n, Mmus\Pla2g4e, Mmus\Syt4, Mmus\Sytl3, Mmus\Pla2g4f, Mmus\Syt17, Mmus\Syt9, Mmus\Syt5, Mmus\Syt8, Mmus\Syt15, Mmus\Syt10, Mmus\Syt6, Mmus\Pla2g4d, Mmus\Syt2, Mmus\Sytl4, Mmus\Syt3, Mmus\Syt11, Mmus\Pla2g4b" "Hsap\SYT2, Hsap\SYT7, Hsap\PLA2G4F, Hsap\SYT10, Hsap\SYT6, Hsap\SYT16, Hsap\TC2N, Hsap\PLA2G4E, Hsap\SYT9, Hsap\SYT15, Hsap\SYTL4, Hsap\SYTL2, Hsap\SYT11, Hsap\SYT3, Hsap\SYT17, Hsap\SYT8, Hsap\SYTL3, Hsap\SYT4, Hsap\PLA2G4D, Hsap\SYT5, Hsap\PLA2G4B" FBgn0031600 CG3652 - http://flybase.org/reports/FBgn0031600 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006977 CG3652 IPR006977:Yip1 domain CG3652 11-Aug-17 DroID_v2017_08 Drer\yipf6 Scer\YIP4 Cele\W02D9.2 Xtro\yipf6 Mmus\Yipf6 Hsap\YIPF6 viable FBgn0034073 CG8414 - http://flybase.org/reports/FBgn0034073 protein_coding_gene polynucleotide 5'-hydroxyl-kinase activity ; GO:0051731 | inferred from sequence or structural similarity with UniProtKB:Q07845 polynucleotide 5'-hydroxyl-kinase activity ; GO:0051731 | inferred from biological aspect of ancestor with PANTHER:PTN000978836 "cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000448 | inferred from biological aspect of ancestor with PANTHER:PTN000298031 rRNA processing ; GO:0006364 | inferred from sequence or structural similarity with UniProtKB:Q07845" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000978836 CG8414 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR032319:Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain" CG8414 11-Aug-17 DroID_v2017_08 Drer\nol9 Scer\GRC3 Cele\nol-9 Xtro\clp1 Mmus\Nol9 Hsap\NOL9 "lethal,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0001073 Fs(3)Zom Female sterile (3) Zombor http://flybase.org/reports/FBgn0001073 - gene molecular_function ; GO:0003674 | no biological data available pronuclear fusion ; GO:0007344 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Zom, Fs(3)Zombor, Fs(3)Sz26, Fs(3)Zom" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "male pronucleus | maternal effect,female pronucleus | maternal effect" FBgn0020876 anon-G36 anon-G36 http://flybase.org/reports/FBgn0020876 - gene - - - "2-P50, 2-G36, anon-G36" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,fertile" FBgn0010205 l(1)GSB lethal (1) GSB http://flybase.org/reports/FBgn0010205 - gene - - - l(1)GSB - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003625 Su(var)309 Suppressor of variegation 309 http://flybase.org/reports/FBgn0003625 - gene - - - Su(var)309 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant" FBgn0065592 l(2)SH0897 lethal (2) SH0897 http://flybase.org/reports/FBgn0065592 gene - - - "l(2)SH0897, l(2)SH2 0897" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036393 CG17362 - http://flybase.org/reports/FBgn0036393 protein_coding_gene - - - CG17362 - CG17362 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036710 CG6479 - http://flybase.org/reports/FBgn0036710 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype - CG6479 IPR019176:Cytochrome B561-related CG6479 11-Aug-17 DroID_v2017_08 Drer\tmem209 - Cele\B0464.6 Xtro\tmem209 Mmus\Tmem209 Hsap\TMEM209 "immune response defective,viable,visible,body color defective" mesothoracic tergum DRSC10647 EK 0.096895975 -0.865872244 0.321626598 -1.516851023 1.515679083 0.314707782 FBgn0069329 X-115-40 X-115-40 http://flybase.org/reports/FBgn0069329 gene molecular_function ; GO:0003674 | no biological data available nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-115-40 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,neurogenic phenotype,recessive,some die during embryonic stage" FBgn0040684 CG12589 - http://flybase.org/reports/FBgn0040684 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12589 - CG12589 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011953 tRNA:Arg-TCG-1-1 transfer RNA:Arginine-TCG 1-1 http://flybase.org/reports/FBgn0011953 "FBgn0011947, FBgn0052610, FBgn0060084" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA[arg], ArgDm, AE002593.trna12-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593, CR32610, tRNA:arg12Ef, tRNA:arg12DE, chrX.trna21-ArgTCG, tRNA-Arg-TCG-1-1, tRNA:Arg-TCG-1-1, tRNA:R:12Ef, CGA" - CR32610 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004540 l(4)102EFd lethal (4) 102EFd http://flybase.org/reports/FBgn0004540 - gene - - - "l(4)39, l(4)102EFd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043989 Su(rst)E124 Su(rst)E124 http://flybase.org/reports/FBgn0043989 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E124, Su(rst)E124" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041784 S(Sev-CycE)D2 S(Sev-CycE)D2 http://flybase.org/reports/FBgn0041784 gene - - - S(Sev-CycE)D2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038566 CG14317 - http://flybase.org/reports/FBgn0038566 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "anon-WO0172774.95, CG14317" "IPR032675:Leucine-rich repeat domain, L domain-like" CG14317 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031558 CG16704 - http://flybase.org/reports/FBgn0031558 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CT37177, BcDNA:RH31195, CG16704" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG16704 11-Aug-17 DroID_v2017_08 "Drer\tfpi2, Drer\tfpia, Drer\spint1b, Drer\si:dkeyp-73b11.8, Drer\si:dkey-117n7.5, Drer\ambp, Drer\col6a4a, Drer\spint2, Drer\spint1a" - "Cele\Y49G5A.1, Cele\piit-1, Cele\ZC504.1, Cele\R12A1.3, Cele\C34F6.1, Cele\K01C8.2, Cele\W05B2.2" "Xtro\spint1, Xtro\spint2, Xtro\ambp, Xtro\tfpi2" "Mmus\Wfdc8, Mmus\Tfpi2, Mmus\Ambp, Mmus\Spint5, Mmus\Spint4, Mmus\Eppin, Mmus\Tfpi, Mmus\Wfdc6b, Mmus\Spint1, Mmus\Wfdc6a, Mmus\Spint2, Mmus\Spint3" "Hsap\TFPI, Hsap\WFIKKN1, Hsap\SPINT2, Hsap\SPINT1, Hsap\WFDC6, Hsap\WFDC8, Hsap\AMBP, Hsap\TFPI2, Hsap\SPINT4, Hsap\SPINT3, Hsap\EPPIN-WFDC6" viable FBgn0037562 CG11671 - http://flybase.org/reports/FBgn0037562 protein_coding_gene - neuromuscular process ; GO:0050905 | inferred from genetic interaction with CG3740 - "BcDNA:GM23845, CG11671" IPR033369:Protein C19orf12 homologue CG11671 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-260e23.8, Drer\zgc:112052, Drer\zgc:101715, Drer\si:ch211-260e23.7" - - Xtro\c19orf12 Mmus\1600014C10Rik Hsap\C19orf12 viable FBgn0065257 l(2)SH2103 lethal (2) SH2103 http://flybase.org/reports/FBgn0065257 gene - - - "l(2)SH2103, l(2)SH2 2103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011695 EbpIII Ejaculatory bulb protein III http://flybase.org/reports/FBgn0011695 "FBgn0034960, FBgn0062902" protein_coding_gene - response to virus ; GO:0009615 | inferred from expression pattern post-mating behavior ; GO:0045297 | inferred from sequence or structural similarity with UniProtKB:Q9U6L5 metamorphosis ; GO:0007552 | inferred from expression pattern extracellular region ; GO:0005576 | non-traceable author statement extracellular region ; GO:0005576 | inferred from sequence model extracellular region ; GO:0005576 | inferred from direct assay "CG11390, phk-2, Phk-2, PEB, PEBmeIII, BcDNA:RH74005, DmelCSP2, PEBmelIII, PebIII, EbpIII" IPR005055:Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 CG11390 11-Aug-17 DroID_v2017_08 Drer\ifit15 - - - - - viable DRSC04638 E -0.185157191 -1.362083093 -1.301704825 2.018970131 0.464766036 0.605413067 FBgn0027374 RevIII-3y RevIII-3y http://flybase.org/reports/FBgn0027374 - gene - - - RevIII-3y - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000379 cru cream underscored http://flybase.org/reports/FBgn0000379 - gene - - - "cr-u, cru" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,recessive" "pigment cell,Malpighian tubule" FBgn0014172 fs(3)93Ca fs(3)93Ca http://flybase.org/reports/FBgn0014172 - gene - - - fs(3)93Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0023143 Uba1 Ubiquitin activating enzyme 1 http://flybase.org/reports/FBgn0023143 "FBgn0010538, FBgn0010605, FBgn0010688" protein_coding_gene ubiquitin activating enzyme activity ; GO:0004839 | inferred from direct assay Atg8 activating enzyme activity ; GO:0019779 | NOT inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay protein ubiquitination ; GO:0016567 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype regulation of Ras protein signal transduction ; GO:0046578 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from direct assay cell proliferation ; GO:0008283 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from mutant phenotype regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype inferred from genetic interaction with hid mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of growth ; GO:0040008 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay dendrite ; GO:0030425 | inferred from mutant phenotype "CG1782, uba-1, DmUba1, Uba 1, UBA-1, E1, 2/31, l(2)03405, l(2)05642, l(2)s3484, Uba1, uba1, FBtr0088499" "IPR018074:Ubiquitin-activating enzyme E1, conserved site, IPR018075:Ubiquitin-activating enzyme E1, IPR000011:Ubiquitin/SUMO-activating enzyme E1, IPR000594:THIF-type NAD/FAD binding fold, IPR018965:Ubiquitin-activating enzyme E1, C-terminal, IPR019572:Ubiquitin-activating enzyme, catalytic cysteine domain, IPR032418:Ubiquitin-activating enzyme E1, FCCH domain, IPR032420:Ubiquitin-activating enzyme E1, four-helix bundle, IPR033127:Ubiquitin-activating enzyme E1, Cys active site" CG1782 11-Aug-17 DroID_v2017_08 "Drer\uba1, Drer\si:dkey-82j4.2, Drer\uba7" Scer\UBA1 Cele\uba-1 "Xtro\uba6, Xtro\LOC100495145" "Mmus\Uba7, Mmus\Uba1y, Mmus\Uba6, Mmus\Uba1" "Hsap\UBA1, Hsap\UBA7, Hsap\UBA6" "neuroanatomy defective,somatic clone,lethal,recessive,visible,partially lethal - majority die,cell lethalcell lethal,heat sensitive,decreased cell death,increased cell death,increased cell number,cell non-autonomous,lethal - all die before end of pupal stage,some die during pupal stage" "adult mushroom body,somatic clone,macrochaeta,dendritic arborizing neuron,neuroblast,dendrite | somatic clone,mushroom body & axon | somatic clone,eye,eye disc,intersegmental nerve,anterior fascicle & synapse | supernumerary,anterior fascicle & synapse,heat sensitive,eye-antennal disc,inter-ommatidial cell,retina,eye disc posterior to the morphogenetic furrow,cell non-autonomous,leg,proboscis,humeral disc" FBgn0015461 l(2)37CDf lethal (2) 37CDf http://flybase.org/reports/FBgn0015461 - gene - - - "l(2)E27, l(2)37CDf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002399 l(3)96Fc lethal (3) 96Fc http://flybase.org/reports/FBgn0002399 - gene - - - "C3, l(3)C3, l(3)96Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001031 Fs(3)Boj Female sterile (3) Bojla http://flybase.org/reports/FBgn0001031 - gene - - - "Boj, Fs(3)Bojla, Fs(3)Sz5, Fs(3)Boj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" female pronucleus | maternal effect FBgn0003049 pd purpleoid http://flybase.org/reports/FBgn0003049 - gene - - - pd - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semidominant,eye color defective" pigment cell FBgn0051437 CG31437 - http://flybase.org/reports/FBgn0051437 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31437 IPR008160:Collagen triple helix repeat CG31437 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0022322 l(1)B23.2 lethal (1) B23.2 http://flybase.org/reports/FBgn0022322 - gene - - - "B23.2, l(1)B23.2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060391 l(3)S133801 lethal (3) S133801 http://flybase.org/reports/FBgn0060391 gene - - - "1338/01, l(3)S133801" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0034758 CG13510 - http://flybase.org/reports/FBgn0034758 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cold acclimation ; GO:0009631 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available CG13510 IPR006629:LPS-induced tumour necrosis factor alpha factor CG13510 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-202h22.7, Drer\si:ch211-202h22.8, Drer\litaf, Drer\si:ch211-202h22.9, Drer\si:dkeyp-75b4.8, Drer\si:ch211-157c3.4, Drer\cdip1" - "Cele\B0348.1, Cele\F16F9.1, Cele\Y22D7AL.15, Cele\Y40H7A.11, Cele\Y37D8A.8, Cele\Y87G2A.18, Cele\Y37D8A.26, Cele\C08E8.1, Cele\Y37D8A.6, Cele\F36G3.3, Cele\B0348.2, Cele\Y87G2A.19" Xtro\litaf "Mmus\Cdip1, Mmus\Litaf" "Hsap\LITAF, Hsap\CDIP1" viable FBgn0038148 CG14377 - http://flybase.org/reports/FBgn0038148 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14377 - CG14377 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003988 Vno Vein off http://flybase.org/reports/FBgn0003988 - gene - - - Vno - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "wing vein L2,wing vein L4,wing vein L5,wing vein,wing vein L3,wing margin bristle" FBgn0000354 cp clipped http://flybase.org/reports/FBgn0000354 - gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "E(nd)88, cp, Cp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,wing margin bristle" FBgn0044080 E(rst)H54 E(rst)H54 http://flybase.org/reports/FBgn0044080 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H54, E(rst)H54" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0034368 CG5482 - http://flybase.org/reports/FBgn0034368 protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 FK506 binding ; GO:0005528 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 endomembrane system ; GO:0012505 | inferred from direct assay CG5482 "IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR019734:Tetratricopeptide repeat" CG5482 11-Aug-17 DroID_v2017_08 "Drer\fkbp16, Drer\fkbp5, Drer\fkbp4, Drer\fkbp8, Drer\fkbp6" Scer\FPR1 - "Xtro\fkbp6, Xtro\fkbp8, Xtro\fkbp4" "Mmus\Fkbp8, Mmus\Fkbp5, Mmus\Fkbp4, Mmus\Fkbp6" "Hsap\FKBP8, Hsap\FKBP6, Hsap\FKBP5, Hsap\FKBP4" lethal FBgn0039687 Naa40 N(alpha)-acetyltransferase 40 http://flybase.org/reports/FBgn0039687 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 phagocytosis ; GO:0006909 | inferred from mutant phenotype - "Naa40, CG7593" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG7593 11-Aug-17 DroID_v2017_08 "Drer\LOC101882407, Drer\naa40" Scer\NAT4 Cele\Y38A10A.7 Xtro\naa40 Mmus\Naa40 Hsap\NAA40 "viable,fertile" FBgn0029914 CG4558 - http://flybase.org/reports/FBgn0029914 protein_coding_gene - - - CG4558 - CG4558 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266657 CR45164 - http://flybase.org/reports/FBgn0266657 non_protein_coding_gene - - - CR45164 - CR45164 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065608 l(2)SH0842 lethal (2) SH0842 http://flybase.org/reports/FBgn0065608 gene - - - "l(2)SH0842, l(2)SH2 0842" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038799 MFS9 Major Facilitator Superfamily Transporter 9 http://flybase.org/reports/FBgn0038799 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "CG4288, MFS9" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG4288 11-Aug-17 DroID_v2017_08 "Drer\slc17a6b, Drer\slc17a5, Drer\slc17a8, Drer\slc17a7a, Drer\slc17a9a, Drer\slc17a6a, Drer\ppt1" "Scer\DAL5, Scer\YIL166C, Scer\FEN2, Scer\THI73, Scer\TNA1" "Cele\slc-17.2, Cele\slc-17.1, Cele\eat-4, Cele\vglu-2, Cele\vglu-3" "Xtro\slc17a5, Xtro\slc17a7" "Mmus\Slc17a8, Mmus\Slc17a2, Mmus\Slc17a5, Mmus\Slc17a7, Mmus\Slc17a1, Mmus\Slc17a3, Mmus\Slc17a6, Mmus\Slc17a4" "Hsap\SLC17A4, Hsap\SLC17A2, Hsap\SLC17A6, Hsap\SLC17A5, Hsap\SLC17A1, Hsap\SLC17A8, Hsap\SLC17A7, Hsap\SLC17A3" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0267505 pre-rRNA:CR45845 ribosomal RNA primary transcript:CR45845 http://flybase.org/reports/FBgn0267505 rRNA_gene - - - "pre-rRNA:CR45845, CR45845" - CR45845 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054027 CG34027 - http://flybase.org/reports/FBgn0054027 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1028, CG34027" - CG34027 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039967 CG17925 - http://flybase.org/reports/FBgn0039967 protein_coding_gene - - - CG17925 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265383 CR44324 - http://flybase.org/reports/FBgn0265383 non_protein_coding_gene - - - CR44324 - CR44324 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003219 rdm reduced macros http://flybase.org/reports/FBgn0003219 - gene - - - rdm - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male fertile,viable,male,poor" "macrochaeta,wing,eye" FBgn0085171 CycA-PRE Cyclin A Polycomb group response element http://flybase.org/reports/FBgn0085171 regulatory_region - - - CycA-PRE - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001944 l(2)26Ae lethal (2) 26Ae http://flybase.org/reports/FBgn0001944 - gene - - - "l(2)gdh-6, l(2)26Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053734 snmRNA:430:CR33734 snmRNA:430:CR33734 http://flybase.org/reports/FBgn0053734 non_protein_coding_gene - - - "CR33734, snmRNA:430:CR33734" - CR33734 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065298 l(2)SH1995 lethal (2) SH1995 http://flybase.org/reports/FBgn0065298 gene - - - "l(2)SH1995, l(2)SH2 1995" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060732 l(3)S067210b lethal (3) S067210b http://flybase.org/reports/FBgn0060732 gene - - - "0672/10, l(3)S067210b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019855 anon-IX anon-IX http://flybase.org/reports/FBgn0019855 - gene - - - "IX, anon-IX" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033766 CG8771 - http://flybase.org/reports/FBgn0033766 protein_coding_gene structural constituent of nuclear pore ; GO:0017056 | inferred from sequence or structural similarity with SGD:S000004571 structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN001265616 RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN001265616 nuclear pore organization ; GO:0006999 | inferred from sequence or structural similarity with SGD:S000004571 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN001265616 nuclear pore inner ring ; GO:0044611 | inferred from sequence or structural similarity with SGD:S000004571 nuclear pore inner ring ; GO:0044611 | inferred from biological aspect of ancestor with PANTHER:PTN001265616 "CG8771, Nup188" IPR018864:Nucleoporin Nup188 CG8771 11-Aug-17 DroID_v2017_08 Drer\nup188 Scer\NUP188 - Xtro\nup188 Mmus\Nup188 Hsap\NUP188 "smell perception defective,female limited,viable" DRSC29937 K 0.288062629 -0.40709298 0.135832807 0.152286318 0.197661336 1.581169659 FBgn0028895 CG17328 - http://flybase.org/reports/FBgn0028895 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "DS02740.8, BG:DS02740.8, CG17328" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17328 11-Aug-17 DroID_v2017_08 Drer\si:ch211-241b2.4 "Scer\AZF1, Scer\ZAP1" "Cele\blmp-1, Cele\ztf-23, Cele\klf-3, Cele\Y55F3AM.14, Cele\M03D4.4, Cele\eor-1, Cele\sem-4, Cele\ztf-14" "Xtro\hic1, Xtro\sp1, Xtro\maz" "Mmus\Zfp189, Mmus\Zfp524, Mmus\Zbtb49" "Hsap\ZNF581, Hsap\ZNF135, Hsap\ZNF524, Hsap\ZNF668, Hsap\ZNF70, Hsap\ZNF560" viable FBgn0024987 ssx sister-of-Sex-lethal http://flybase.org/reports/FBgn0024987 FBgn0027771 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002343 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity defense response to bacterium ; GO:0042742 | inferred from mutant phenotype - "EG:132E8.1, cg3056, anon-EST:Posey102, ssx, CG3056" "IPR000504:RNA recognition motif domain, IPR002343:Paraneoplastic encephalomyelitis antigen" CG3056 11-Aug-17 DroID_v2017_08 "Drer\hug, Drer\elavl2" "Scer\PAB1, Scer\GBP2" Cele\exc-7 "Xtro\elavl4, Xtro\elavl2, Xtro\elavl1, Xtro\elavl3" "Mmus\Elavl3, Mmus\Elavl4, Mmus\Elavl1, Mmus\Elavl2" "Hsap\ELAVL1, Hsap\ELAVL2, Hsap\ELAVL3, Hsap\ELAVL4" "viable,male fertile,female fertile,fertile" DRSC18492 I 1.645503872 -1.930822612 0.323124438 -1.309049388 -0.236162532 0.172936914 FBgn0040833 CG7498 - http://flybase.org/reports/FBgn0040833 protein_coding_gene - - - CG7498 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065131 l(3)SH131 lethal (3) SH131 http://flybase.org/reports/FBgn0065131 gene - - - "l(3)SH131, l(2)SH3 131" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033890 Ctf4 Chromosome transmission fidelity 4 http://flybase.org/reports/FBgn0033890 protein_coding_gene - mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype preblastoderm mitotic cell cycle ; GO:0035185 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype - "anon-WO0140519.180, CG13350, Ctf4" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR022100:Minichromosome loss protein Mcl1, middle region, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG13350 11-Aug-17 DroID_v2017_08 Drer\wdhd1 Scer\CTF4 "Cele\F17C11.10, Cele\oct-2" Xtro\wdhd1 Mmus\Wdhd1 Hsap\WDHD1 "mitotic cell cycle defective,endomitotic cell cycle defective,chemical sensitive,lethal,some die during immature adult stage,recessive,maternal effect,heat sensitive,visible,partially lethal - majority die,some die during pupal stage" "polytene chromosomeAct.PU,mesothoracic tergum" FBgn0264390 CR43838 - http://flybase.org/reports/FBgn0264390 non_protein_coding_gene - - - "CR43838, lincRNA.1030" - CR43838 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025833 CG8910 - http://flybase.org/reports/FBgn0025833 FBgn0044651 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN001197468 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001197468 "EG:EG0003.1, anon-WO0140519.220, CG8910" "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8910 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0030710 CG8924 - http://flybase.org/reports/FBgn0030710 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 "CG8924, CC9" "IPR007889:DNA binding HTH domain, Psq-type, IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG8924 11-Aug-17 DroID_v2017_08 - - - - Mmus\Bach2 "Hsap\ZBTB14, Hsap\ZBTB12, Hsap\BACH2, Hsap\BACH1, Hsap\ZBTB9, Hsap\ZBTB37, Hsap\ZBTB43" viable FBgn0052475 mthl8 methuselah-like 8 http://flybase.org/reports/FBgn0052475 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "mthl8, Mth-8, CG32475, CG13406, CG11869, anon-WO0170980.146, anon-WO0170980.145, mthl-8" "IPR010596:Methuselah, N-terminal domain, IPR023311:Methuselah ectodomain, domain 2" CG32475 11-Aug-17 DroID_v2017_08 Drer\adgrg6 - Cele\lat-2 Xtro\gpr157 Mmus\Adgre1 Hsap\ADGRF3 viable FBgn0034670 CG13488 - http://flybase.org/reports/FBgn0034670 protein_coding_gene - - - CG13488 - CG13488 11-Aug-17 DroID_v2017_08 - - Cele\Y17G9A.3 - - - viable FBgn0015949 hrg hiiragi http://flybase.org/reports/FBgn0015949 "FBgn0022078, FBgn0034465, FBgn0040293" protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR007010, InterPro:IPR011068 polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from biological aspect of ancestor with PANTHER:PTN000074206 polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from direct assay polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from sequence or structural similarity with SGD:S000001710" mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000074206 mRNA polyadenylation ; GO:0006378 | inferred from sequence or structural similarity with SGD:S000001710 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000074206 "l(2)07619, CG9854, PAP, Pap, l(2)k07619, hrg" "IPR002934:Polymerase, nucleotidyl transferase domain, IPR007010:Poly(A) polymerase, RNA-binding domain, IPR007012:Poly(A) polymerase, central domain, IPR011068:Nucleotidyltransferase, class I, C-terminal-like, IPR014492:Poly(A) polymerase" CG9854 11-Aug-17 DroID_v2017_08 "Drer\papola, Drer\papolg" Scer\PAP1 "Cele\pap-1, Cele\T15H9.6, Cele\F43G6.5" "Xtro\papola, Xtro\papolg" "Mmus\Papolb, Mmus\Papola, Mmus\Papolg" "Hsap\PAPOLA, Hsap\PAPOLG, Hsap\PAPOLB" "lethal,recessive,viable,fertile,lethal - all die before end of larval stage,partially,some die during larval stage,visible,wild-type,cell lethal,germline clone" "crystal cell,plasmatocyte,wing,dorsal bridge" FBgn0083306 E(smoDN)1496 Enhancer of smoDN 1496 http://flybase.org/reports/FBgn0083306 gene - - - E(smoDN)1496 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065417 l(2)SH1535 lethal (2) SH1535 http://flybase.org/reports/FBgn0065417 gene - - - "l(2)SH1535, l(2)SH2 1535" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039332 alrm astrocytic leucine-rich repeat molecule http://flybase.org/reports/FBgn0039332 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT37074, CG11910, alrm, Alrm" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG11910 11-Aug-17 DroID_v2017_08 - - - Xtro\ecm2.2 "Mmus\Lrrc9, Mmus\Lingo3" - viable FBgn0025835 CG17707 - http://flybase.org/reports/FBgn0025835 - protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - "EG:23E12.3, CG17707" "IPR006621:Nose resistant-to-fluoxetine protein, N-terminal, IPR002656:Acyltransferase 3" CG17707 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-14, Cele\oac-54, Cele\oac-55, Cele\oac-3, Cele\oac-39, Cele\ndg-4, Cele\oac-46, Cele\oac-53, Cele\oac-9, Cele\oac-6, Cele\oac-32, Cele\oac-31, Cele\nrf-6, Cele\rhy-1, Cele\oac-5, Cele\oac-7, Cele\oac-50, Cele\oac-20" - Mmus\Oacyl - viable FBgn0005019 dkb dark bubbly http://flybase.org/reports/FBgn0005019 - gene - - - dkb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,body color defective" adult thorax & cuticle FBgn0259296 EP-24 - http://flybase.org/reports/FBgn0259296 gene - - - EP-24 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0039198 CG5768 - http://flybase.org/reports/FBgn0039198 protein_coding_gene - - - CG5768 IPR006631:Protein of unknown function DM4/12 CG5768 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0013441 fop fop http://flybase.org/reports/FBgn0013441 - gene - - - fop - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016839 l(1)MZ8 lethal (1) MZ8 http://flybase.org/reports/FBgn0016839 - gene - - - "l(1)MZ8, M8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027979 l(3)S137908 lethal (3) S137908 http://flybase.org/reports/FBgn0027979 gene - - - "1379/08, l(3)S137908" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0050350 CG30350 - http://flybase.org/reports/FBgn0050350 protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 - "CG8278, CG30350" "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR029000:Cyclophilin-like domain, IPR029488:Hemingway/KIAA1430" CG30350 11-Aug-17 DroID_v2017_08 "Drer\ppifa, Drer\nphs1, Drer\ppiaa, Drer\ppiab, Drer\ppifb" "Scer\CPR3, Scer\CPR1" - "Xtro\ppif, Xtro\ppia, Xtro\nphs1" "Mmus\Ranbp2, Mmus\Ppia, Mmus\Ppif, Mmus\Nphs1" "Hsap\PPIAL4E, Hsap\PPIAL4C, Hsap\PPIAL4A, Hsap\PPIAL4D, Hsap\PPIA, Hsap\LOC105371242, Hsap\PPIF, Hsap\NPHS1, Hsap\PPIAL4G, Hsap\RANBP2" FBgn0028196 l(3)S022231b lethal (3) S022231b http://flybase.org/reports/FBgn0028196 gene - - - "l(3)S022231, 0222/31, l(3)S022231b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0047306 CR32314 - http://flybase.org/reports/FBgn0047306 non_protein_coding_gene - - - "BcDNA:GH25089, CR32314" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038944 CG5388 - http://flybase.org/reports/FBgn0038944 protein_coding_gene - - - CG5388 - CG5388 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0016711 Reg-16 Rhythmically expressed gene 16 http://flybase.org/reports/FBgn0016711 - gene - - - "Dreg-16, Reg-16" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | late , adult stage " adult head

FBgn0267078 CR45522 - http://flybase.org/reports/FBgn0267078 non_protein_coding_gene - - - CR45522 - CR45522 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262030 CG42841 - http://flybase.org/reports/FBgn0262030 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42841 - CG42841 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002410 l(3)99Ea lethal (3) 99Ea http://flybase.org/reports/FBgn0002410 - gene - - - l(3)99Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022713 2Ab17 2Ab17 http://flybase.org/reports/FBgn0022713 - gene - - - "p2Ab17, 2Ab17" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053096 CG33096 - http://flybase.org/reports/FBgn0053096 protein_coding_gene - - plasma membrane ; GO:0005886 | inferred from direct assay "CG11935, CG33096" "IPR029058:Alpha/Beta hydrolase fold, IPR022742:Serine aminopeptidase, S33" CG33096 11-Aug-17 DroID_v2017_08 "Drer\abhd17ab, Drer\si:ch211-117n7.7, Drer\abhd13, Drer\si:ch211-117n7.6, Drer\abhd17b, Drer\abhd17c, Drer\abhd12, Drer\abhd17aa" Scer\YNL320W "Cele\F01D5.7, Cele\Y71G12A.4, Cele\F01D5.8, Cele\aho-3, Cele\Y41E3.18" "Xtro\abhd13, Xtro\abhd12, Xtro\abhd17c, Xtro\abhd17a, Xtro\abhd17b" "Mmus\Abhd12b, Mmus\Abhd17c, Mmus\Abhd17a, Mmus\Abhd13, Mmus\Abhd17b, Mmus\Abhd12" "Hsap\ABHD13, Hsap\ABHD12, Hsap\ABHD17B, Hsap\ABHD17A, Hsap\ABHD12B, Hsap\ABHD17C" viable FBgn0062532 ff6 ff6 http://flybase.org/reports/FBgn0062532 gene - - - ff6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,mitotic cell cycle defective" "spermatid,meiotic cell cycle | male,centriole,spindle" FBgn0005059 fs(2)OW105 female sterile (2) OW105 http://flybase.org/reports/FBgn0005059 - gene - - - fs(2)OW105 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033426 CG1814 - http://flybase.org/reports/FBgn0033426 protein_coding_gene 5'-nucleotidase activity ; GO:0008253 | inferred from biological aspect of ancestor with PANTHER:PTN000250728 single-stranded DNA binding ; GO:0003697 | inferred from sequence or structural similarity with SGD:S000006223 cellular response to DNA damage stimulus ; GO:0006974 | inferred from sequence or structural similarity with HGNC:16147 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:16147 "CG1814, 45551045, 45550393" "IPR008380:HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase, IPR016695:Purine 5'-nucleotidase, IPR023214:HAD-like domain" CG1814 11-Aug-17 DroID_v2017_08 "Drer\nt5dc3, Drer\nt5dc2" - - "Xtro\nt5dc3, Xtro\nt5dc2" "Mmus\Nt5dc2, Mmus\Nt5dc3" "Hsap\NT5DC3, Hsap\NT5DC2" viable DRSC06711 IE 2.760233289 1.255609314 1.976211852 -1.520704885 -0.097523954 0.302923685 FBgn0050351 CG30351 - http://flybase.org/reports/FBgn0050351 protein_coding_gene - - - CG30351 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262853 CR43217 - http://flybase.org/reports/FBgn0262853 pseudogene_attribute - - - "CR43217, noncoding_23159, noncoding_23161" - CR43217 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058190 CG40190 - http://flybase.org/reports/FBgn0058190 protein_coding_gene - - - CG40190 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263452 CR43475 - http://flybase.org/reports/FBgn0263452 non_protein_coding_gene - - - CR43475 - CR43475 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037478 CG2656 - http://flybase.org/reports/FBgn0037478 protein_coding_gene GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000477654 RNA polymerase III complex localization to nucleus ; GO:1990022 | inferred from biological aspect of ancestor with PANTHER:PTN000477655 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype RNA polymerase II complex import to nucleus ; GO:0044376 | inferred from biological aspect of ancestor with PANTHER:PTN000477655 neurogenesis ; GO:0022008 | inferred from mutant phenotype - "NEST:bs33f03, CG2656" "IPR004130:GPN-loop GTPase, IPR030228:GPN-loop GTPase 3, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2656 11-Aug-17 DroID_v2017_08 Drer\gpn3 Scer\GPN3 Cele\Y75B8A.14 Xtro\gpn3 Mmus\Gpn3 Hsap\GPN3 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell" FBgn0262366 CG43064 - http://flybase.org/reports/FBgn0262366 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43064, MIP22993" "IPR032675:Leucine-rich repeat domain, L domain-like" CG43064 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042156 CG18833 - http://flybase.org/reports/FBgn0042156 protein_coding_gene - - - CG18833 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058394 CG40394 - http://flybase.org/reports/FBgn0058394 protein_coding_gene - - - CG40394 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004677 e(fa[swb]) enhancer of facet-strawberry http://flybase.org/reports/FBgn0004677 - gene - - - "fa[swb-h], e(fa[swb])fa[swb], e(fa[swb])" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000672 fliG flightless G http://flybase.org/reports/FBgn0000672 - gene - flight behavior ; GO:0007629 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype - fliG - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,visible,lethal,cold sensitive,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing vein" FBgn0002114 l(2)bl lethal (2) bluter http://flybase.org/reports/FBgn0002114 - gene - - - l(2)bl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0034804 CG3831 - http://flybase.org/reports/FBgn0034804 protein_coding_gene - - - CG3831 - CG3831 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034914 CG5554 - http://flybase.org/reports/FBgn0034914 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017937 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607" endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity CG5554 "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site" CG5554 11-Aug-17 DroID_v2017_08 "Drer\tmx4, Drer\tmx1" "Scer\PDI1, Scer\EPS1, Scer\EUG1" "Cele\C03H12.1, Cele\dpy-11" "Xtro\tmx1, Xtro\tmx4" "Mmus\Tmx1, Mmus\Tmx4" "Hsap\TMX1, Hsap\TMX4" viable FBgn0033089 CG17266 - http://flybase.org/reports/FBgn0033089 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay CG17266 "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG17266 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-55a19.2, Drer\ppib, Drer\ppiab, Drer\nktr, Drer\ppil6, Drer\ppid, Drer\ppiaa, Drer\ppig, Drer\LOC100333141, Drer\ppie, Drer\ppih" "Scer\CPR4, Scer\CPR8, Scer\CPR2, Scer\CPR7, Scer\CPR5, Scer\CPR6" "Cele\Y17G9B.4, Cele\cyn-9, Cele\cyn-11, Cele\cyn-1, Cele\cyn-5, Cele\cyn-3, Cele\cyn-2, Cele\cyn-8, Cele\cyn-6" "Xtro\ranbp2, Xtro\ppic, Xtro\ppib, Xtro\ppie, Xtro\ppil6, Xtro\ppid, Xtro\ppia, Xtro\ppih, Xtro\nktr" "Mmus\Ranbp2, Mmus\Nktr, Mmus\Ppid, Mmus\Ppie, Mmus\Ppia, Mmus\Ppif, Mmus\Ppil6, Mmus\Ppic, Mmus\Ppib, Mmus\Ppih, Mmus\Ppig" "Hsap\LOC105371242, Hsap\PPIAL4D, Hsap\PPIC, Hsap\RGPD8, Hsap\PPIE, Hsap\RGPD5, Hsap\PPIA, Hsap\RGPD6, Hsap\PPIAL4C, Hsap\RANBP2, Hsap\NKTR, Hsap\PPIAL4G, Hsap\PPID, Hsap\PPIF, Hsap\RGPD2, Hsap\RGPD1, Hsap\RGPD4, Hsap\PPIL6, Hsap\PPIAL4A, Hsap\RGPD3, Hsap\PPIG, Hsap\PPIB, Hsap\PPIH" viable FBgn0052757 CG32757 - http://flybase.org/reports/FBgn0052757 protein_coding_gene - - - CG32757 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028583 lcs la costa http://flybase.org/reports/FBgn0028583 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12794, lcs" - CG12794 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0082919 snoRNA:Or-CD4 - http://flybase.org/reports/FBgn0082919 snoRNA_gene - - - "DmOr_cd4 snoRNA, CR34542, snoRNA:Or-CD4, orphan CD4, snoRNA:Or-cd4, DmOr_cd4" - CR34542 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052494 CG32494 - http://flybase.org/reports/FBgn0052494 protein_coding_gene - - - CG32494 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC19222 I -0.568608245 -2.223938461 0.045729701 -0.085418759 -0.539987817 -1.409095899 FBgn0067767 hard-boiled hard boiled http://flybase.org/reports/FBgn0067767 gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - hard-boiled - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0259721 CG42375 - http://flybase.org/reports/FBgn0259721 protein_coding_gene - - mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001884832 "CG42375, CG9288, Dromel_CG9288_FBtr0082829_pyruvatekinasedomain_uORF" IPR013892:Cytochrome c oxidase biogenesis protein Cmc1-like CG42375 11-Aug-17 DroID_v2017_08 Drer\cmc2 "Scer\CMC2, Scer\CMC1" Cele\C35D10.17 Xtro\cmc2 Mmus\Cmc2 Hsap\CMC2 FBgn0019768 l(1)54 lethal (1) 54 http://flybase.org/reports/FBgn0019768 - gene - - - l(1)54 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041717 snRNA:U6atac:29B U6atac snRNA at 29B http://flybase.org/reports/FBgn0041717 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype" U6atac snRNP ; GO:0005691 | inferred from sequence or structural similarity U6atac snRNP ; GO:0005691 | inferred from sequence or structural similarity with HGNC_gene:RNU6ATAC; HGNC:34017 "U6atac, l(2)k01105, U6atac-29B, CR32989, snRNA:U6atac:29B, U6atac:29B" - CR32989 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "crystal cell,imaginal disc" FBgn0085386 CG34357 - http://flybase.org/reports/FBgn0085386 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | NOT inferred from sequence or structural similarity with CG10738 receptor activity ; GO:0004872 | inferred from sequence or structural similarity with Gyc76C guanylate cyclase activity ; GO:0004383 | inferred from sequence or structural similarity with Gyc76C guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245 cGMP biosynthetic process ; GO:0006182 | inferred from sequence or structural similarity with MGI:MGI:106903 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 cGMP-mediated signaling ; GO:0019934 | inferred from sequence or structural similarity with Gyc76C" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Gyc76C" "CG34357, CG14652, CG12585, CG12584, CG41467, GYC, CG9783" "IPR029787:Nucleotide cyclase, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011009:Protein kinase-like domain, IPR000719:Protein kinase domain, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG34357 11-Aug-17 DroID_v2017_08 "Drer\gucy2g, Drer\si:ch73-139e5.4, Drer\npr2, Drer\npr3, Drer\npr1a, Drer\gc3, Drer\gc2, Drer\gucy2f, Drer\gucy2c, Drer\npr1b, Drer\si:dkey-37g12.1, Drer\ints3" - "Cele\gcy-21, Cele\gcy-27, Cele\gcy-17, Cele\daf-11, Cele\odr-1, Cele\gcy-7, Cele\gcy-14, Cele\gcy-1, Cele\gcy-25, Cele\gcy-20, Cele\gcy-15, Cele\gcy-3, Cele\gcy-13, Cele\gcy-12, Cele\gcy-28, Cele\gcy-19, Cele\gcy-22, Cele\gcy-9, Cele\gcy-33, Cele\gcy-4, Cele\gcy-5, Cele\gcy-2, Cele\Y92H12A.4, Cele\gcy-6" "Xtro\gucy2f, Xtro\gucy2c, Xtro\gucy2d, Xtro\npr3, Xtro\npr1" "Mmus\Ints3, Mmus\Npr1, Mmus\Gucy2e, Mmus\Gucy2f, Mmus\Gucy2g, Mmus\Npr2, Mmus\Gucy2d, Mmus\Npr3, Mmus\Gucy2c" "Hsap\INTS3, Hsap\GUCY2C, Hsap\NPR2, Hsap\GUCY2D, Hsap\NPR3, Hsap\GUCY2F, Hsap\NPR1" viable DRSC28043 K -0.144182816 0.347424776 -0.003741696 0.20928351 -1.79188803 0.172604952 FBgn0020340 anon-5Cb anon-5Cb http://flybase.org/reports/FBgn0020340 - gene - - - anon-5Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262770 Su(E1)-D - http://flybase.org/reports/FBgn0262770 gene - - - Su(E1)-D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005761 l(1)TK407 lethal (1) TK407 http://flybase.org/reports/FBgn0005761 - gene - - - "l407, l(1)TK407" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0266780 CR45245 - http://flybase.org/reports/FBgn0266780 non_protein_coding_gene - - - CR45245 - CR45245 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060853 l(3)S048412a lethal (3) S048412a http://flybase.org/reports/FBgn0060853 gene - - - "0484/12, l(3)S048412a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0266151 CR44857 - http://flybase.org/reports/FBgn0266151 non_protein_coding_gene - - - CR44857 - CR44857 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069418 JJF136 JJF136 http://flybase.org/reports/FBgn0069418 gene - - - JJF136 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0002321 l(3)85Ee lethal (3) 85Ee http://flybase.org/reports/FBgn0002321 - gene - - - l(3)85Ee - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030071 CG12661 - http://flybase.org/reports/FBgn0030071 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12661 "IPR008560:Protein of unknown function DUF842, eukaryotic" CG12661 11-Aug-17 DroID_v2017_08 Drer\fam136a - Cele\ZK637.2 Xtro\fam136a Mmus\Fam136a Hsap\FAM136A viable FBgn0267962 CR46242 - http://flybase.org/reports/FBgn0267962 non_protein_coding_gene - - - "CR46242, lincRNA.992" - CR46242 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064210 UY2517 UY2517 http://flybase.org/reports/FBgn0064210 gene - - - UY2517 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0005690 Nc34CD Neural conserved at 34CD http://flybase.org/reports/FBgn0005690 - gene - - - "NC34CD, Nc34CD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267229 CR45669 - http://flybase.org/reports/FBgn0267229 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45669, CR45669" - CR45669 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052187 CG32187 - http://flybase.org/reports/FBgn0052187 protein_coding_gene - - - "CG5584, CG32187, DPLG2" IPR027806:Harbinger transposase-derived nuclease domain CG32187 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-257c13.2, Drer\ids, Drer\si:dkey-174i8.1, Drer\zgc:162945, Drer\sgsh, Drer\arsg, Drer\galns, Drer\harbi1, Drer\LOC559800, Drer\arsa, Drer\zgc:194221, Drer\arsia, Drer\LOC101884179, Drer\arsh, Drer\LOC563783, Drer\LOC100005423, Drer\zgc:113227, Drer\LOC569097, Drer\zmp:0000000634" - - "Xtro\arsd, Xtro\LOC100127800, Xtro\arsi, Xtro\arsj, Xtro\sgsh, Xtro\arsa.1, Xtro\arsb, Xtro\arsh, Xtro\arsk, Xtro\sts, Xtro\ids" "Mmus\Arsb, Mmus\Arsj, Mmus\Sgsh, Mmus\Arsa, Mmus\Arsg, Mmus\Arsi, Mmus\Harbi1, Mmus\Ids, Mmus\Galns" "Hsap\ARSG, Hsap\ARSB, Hsap\STS, Hsap\GALNS, Hsap\ARSH, Hsap\ARSD, Hsap\ARSE, Hsap\IDS, Hsap\ARSI, Hsap\SGSH, Hsap\ARSF, Hsap\HARBI1, Hsap\ARSJ, Hsap\ARSA" "partially lethal - majority die,some die during pupal stage" FBgn0005735 l(1)TK222 lethal (1) TK222 http://flybase.org/reports/FBgn0005735 - gene - - - "l222, l(1)TK222" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0265588 CR44415 - http://flybase.org/reports/FBgn0265588 non_protein_coding_gene - - - CR44415 - CR44415 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058001 CG40001 - http://flybase.org/reports/FBgn0058001 protein_coding_gene - - - CG40001 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015252 M(1)15DEF Minute (1) 15DEF http://flybase.org/reports/FBgn0015252 - gene - - - M(1)15DEF - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,Minute,dominant" FBgn0265979 CR44758 - http://flybase.org/reports/FBgn0265979 non_protein_coding_gene - - - "lincRNA.373, CR44758" - CR44758 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033453 CG1667 - http://flybase.org/reports/FBgn0033453 protein_coding_gene cyclic-di-GMP binding ; GO:0035438 | inferred from electronic annotation with InterPro:IPR033952 positive regulation of type I interferon production ; GO:0032481 | inferred from electronic annotation with InterPro:IPR029158 activation of innate immune response ; GO:0002218 | inferred from electronic annotation with InterPro:IPR029158 - CG1667 "IPR033952:Stimulator of interferon genes protein, C-terminal, IPR029158:Stimulator of interferon genes protein" CG1667 11-Aug-17 DroID_v2017_08 Drer\tmem173 - - Xtro\tmem173 Mmus\Tmem173 Hsap\TMEM173 "partially lethal - majority die,viable" DRSC06615 IE 0.855693288 1.570866329 0.699681934 1.798709251 -0.09406758 -0.464888396 FBgn0085568 CG41240 - http://flybase.org/reports/FBgn0085568 protein_coding_gene - - - CG41240 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083006 snoRNA:Psi28S-1153 snoRNA:Psi28S-1153 http://flybase.org/reports/FBgn0083006 snoRNA_gene - - - "snoRNA:Psi28S-1153, psi28s-1153, Psi 28S-1153, CR34531, chr2R:9073472..9073780" - CR34531 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261856 CR42785 - http://flybase.org/reports/FBgn0261856 pseudogene_attribute - - - "CR42785, noncoding_4773" - CR42785 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032873 CG2614 - http://flybase.org/reports/FBgn0032873 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR013216 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR013216 cellular_component ; GO:0005575 | no biological data available "38D.29, CG2614" "IPR013216:Methyltransferase type 11, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG2614 11-Aug-17 DroID_v2017_08 "Drer\mettl13, Drer\ece2a" - "Cele\C01B10.8, Cele\C17E4.11, Cele\Y34B4A.7" Xtro\mettl13 "Mmus\Ece2, Mmus\Mettl13" "Hsap\METTL13, Hsap\ECE2" viable FBgn0263049 let-7-C let-7-Complex http://flybase.org/reports/FBgn0263049 non_protein_coding_gene - cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype - "CR43344, let-7-C, pri-let-7-C" - CR43344 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,somatic clone,dominant" "mushroom body,somatic clone,adult mushroom body alpha'-lobe,adult mushroom body beta'-lobe,adult mushroom body gamma-lobe" FBgn0065683 l(2)SH0661 lethal (2) SH0661 http://flybase.org/reports/FBgn0065683 gene - - - "l(2)SH0661, l(2)SH2 0661" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002102 l(2)57Dc lethal (2) 57Dc http://flybase.org/reports/FBgn0002102 - gene - - - "l(2)57Ed, l(2)57Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266857 CR45318 - http://flybase.org/reports/FBgn0266857 non_protein_coding_gene - - - CR45318 - CR45318 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003478 splw splay wing http://flybase.org/reports/FBgn0003478 - gene - - - splw - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,viable,male,reduced,visible" "wing,eye" FBgn0004479 l(1)air3 lethal aberrant immune response 3 http://flybase.org/reports/FBgn0004479 - gene - - - l(1)air3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,melanotic mass phenotype" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass" FBgn0267776 CR46107 - http://flybase.org/reports/FBgn0267776 non_protein_coding_gene - - - CR46107 - CR46107 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020224 Cbl Cbl proto-oncogene http://flybase.org/reports/FBgn0020224 "FBgn0035894, FBgn0041253, FBgn0061761" protein_coding_gene "phosphotyrosine binding ; GO:0001784 | inferred from electronic annotation with InterPro:IPR024159 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR003153 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR014741 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:15961 receptor tyrosine kinase binding ; GO:0030971 | inferred from physical interaction with Egfr, Pvr zinc ion binding ; GO:0008270 | inferred from sequence model SH3 domain binding ; GO:0017124 | inferred from biological aspect of ancestor with PANTHER:PTN001124099 ligase activity ; GO:0016874 | traceable author statement phosphotyrosine binding ; GO:0001784 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN001124099 protein binding ; GO:0005515 | inferred from physical interaction with drk" "negative regulation of epidermal growth factor-activated receptor activity ; GO:0007175 | inferred from genetic interaction with drk epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement eye photoreceptor cell differentiation ; GO:0001754 | inferred from direct assay proteolysis ; GO:0006508 | traceable author statement regulation of carbohydrate metabolic process ; GO:0006109 | inferred from mutant phenotype negative regulation of hormone biosynthetic process ; GO:0032353 | inferred from mutant phenotype R7 cell fate commitment ; GO:0007465 | inferred from direct assay germ-line cyst formation ; GO:0048134 | inferred from genetic interaction with Fmr1 negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype negative regulation of epidermal growth factor-activated receptor activity ; GO:0007175 | traceable author statement regulation of cell proliferation ; GO:0042127 | inferred from genetic interaction with Fmr1 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:15961 dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype negative regulation of epidermal growth factor-activated receptor activity ; GO:0007175 | inferred from mutant phenotype regulation of cell death ; GO:0010941 | inferred from direct assay dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | non-traceable author statement endocytosis ; GO:0006897 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR003153 membrane raft ; GO:0045121 | inferred from biological aspect of ancestor with PANTHER:PTN001124099 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001124099 cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CBL, d-cbl, D-cbl, D-Cbl, D-cblL, CG7037, DCbl, cbl, Dv-Cbl, dCbl, Dv-cbl, Dcbl, F165, CG7043, anon-WO0118547.68, Cbl, D-cblS, D-Cbl L, v-Cbl, D-CblL" "IPR015940:Ubiquitin-associated domain, IPR001841:Zinc finger, RING-type, IPR003153:Adaptor protein Cbl, N-terminal helical, IPR011992:EF-hand domain pair, IPR024159:Adaptor protein Cbl, PTB domain, IPR024162:Adaptor protein Cbl, IPR000980:SH2 domain, IPR014741:Adaptor protein Cbl, EF hand-like, IPR014742:Adaptor protein Cbl, SH2-like domain, IPR009060:UBA-like, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7037 11-Aug-17 DroID_v2017_08 "Drer\cblb, Drer\cblc, Drer\cbl" - Cele\sli-1 "Xtro\cblb, Xtro\cbl" "Mmus\Cbl, Mmus\Cblb, Mmus\Cblc" "Hsap\CBLB, Hsap\CBL, Hsap\CBLC" " embryonic stage | stage 1-3 , larval stage | third instar , embryonic stage | early , embryonic stage | blastoderm " " organism

, imaginal disc

" " embryonic stage | stage 15 , embryonic stage | blastoderm , embryonic stage | early " " pharyngeal muscle

, embryonic/larval hindgut

, Malpighian tubule

" "viable,fertile,partially lethal - majority die,male limited,developmental rate defective,starvation stress response defective,short lived,lethal - all die before end of P-stage,some die during P-stage,lethal,recessive,visible,dominant,neuroanatomy defective,large body,oxidative stress response defective,decreased cell death,somatic clone" "egg,chorion,dorsal appendage,wing vein L4,wing vein L5,anterior crossvein,eye,ommatidium,adult abdominal segment,tergite,chorion | maternal effect, with CblF165,maternal effect,wing vein,ectopic,wing,neuron,cephalopharyngeal skeleton,embryonic/first instar larval cuticle,photoreceptor cell,photoreceptor cell R7,somatic clone,chorion | maternal effect | somatic clone,embryo,denticle belt,germline clone,rescuable maternal effect,border follicle cell,chorion | maternal effect, with CblL.Hsp83,primary pigment cell,secondary pigment cell,tertiary pigment cell,abdominal ventral denticle belt" DRSC28169 EK -0.909443407 0.087494379 0.066135572 2.158431619 -1.52115144 -2.508510141 FBgn0046687 Tre1 Trapped in endoderm 1 http://flybase.org/reports/FBgn0046687 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 germ cell migration ; GO:0008354 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity pole cell migration ; GO:0007280 | traceable author statement ectopic germ cell programmed cell death ; GO:0035234 | traceable author statement germ cell development ; GO:0007281 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 cell cortex ; GO:0005938 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "sctt, tre1, CG3171, tre-1, Tre-1, LD12308, BEST:LD12308, anon-WO0170981.1, anon-WO0170980.17, anon-WO0170980.16, Tre1, Tre" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG3171 11-Aug-17 DroID_v2017_08 "Drer\taar10c, Drer\taar10d, Drer\mtnr1ab, Drer\mtnr1aa, Drer\prlhr2b, Drer\gpr19, Drer\prlhr2a, Drer\npy4r, Drer\mtnr1al, Drer\npy1r, Drer\prokr1b, Drer\mchr1a, Drer\gpr88, Drer\npy2rl, Drer\npy2r, Drer\prokr1a, Drer\npy8ar, Drer\mtnr1ba, Drer\mchr1b, Drer\npy8br, Drer\mtnr1c, Drer\mtnr1bb, Drer\gpr84" - "Cele\npr-6, Cele\npr-17, Cele\npr-10" "Xtro\mtnr1c, Xtro\LOC100486065, Xtro\mtnr1b, Xtro\gpr84" "Mmus\Mtnr1a, Mmus\Mtnr1b, Mmus\Npy5r, Mmus\Npy6r, Mmus\Prlhr, Mmus\Gpr88, Mmus\Gpr19, Mmus\Prokr1, Mmus\Gpr50, Mmus\Mchr1, Mmus\Npy1r, Mmus\Prokr2, Mmus\Npy4r, Mmus\Npy2r, Mmus\Gpr84" "Hsap\MTNR1B, Hsap\PRLHR, Hsap\PROKR1, Hsap\GPR84, Hsap\NPY1R, Hsap\GPR19, Hsap\NPY5R, Hsap\NPY2R, Hsap\MCHR1, Hsap\GPR88, Hsap\GPR50, Hsap\NPY4R, Hsap\PROKR2, Hsap\MTNR1A" "chemosensitive behavior defective,viable,fertile,neuroanatomy defective,visible,partially lethal - majority die,lethal,wild-type,female sterile,recessive,rescuable maternal effect,male sterile,maternal effect,short lived,male,starvation stress response defective,female,heat stress response defective" "embryonic neuroblast,presumptive embryonic/larval central nervous system,macrochaeta,eye,wing,germline cell,ectopic,maternal effect,rescuable maternal effect,non-rescuable maternal effect,gonad" FBgn0026164 tRNA:Lys-TTT-2-3 transfer RNA:Lysine-TTT 2-3 http://flybase.org/reports/FBgn0026164 "FBgn0003793, FBgn0011901, FBgn0051489, FBgn0060172" tRNA_gene AAA codon-amino acid adaptor activity ; GO:0033443 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033443 cytosol ; GO:0005829 | inferred by curator from GO:0033443 "CR31489, lys5:84ABb, AE002699.trna10-LysTTT, tRNA:K:TTT:AE002699-e, tRNA:K5, BG:DS00276.2, chr3R.trna3-LysTTT, tRNA-Lys-TTT-2-3, tRNA:Lys-TTT-2-3, tRNA:K5:84ABb, AAA" - CR31489 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039870 CG1896 - http://flybase.org/reports/FBgn0039870 protein_coding_gene - - - CG1896 IPR031974:Programmed cell death protein 7 CG1896 11-Aug-17 DroID_v2017_08 Drer\pdcd7 - - - Mmus\Pdcd7 Hsap\PDCD7 viable FBgn0051374 sals sarcomere length short http://flybase.org/reports/FBgn0051374 protein_coding_gene actin filament binding ; GO:0051015 | inferred from direct assay positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype regulation of sarcomere organization ; GO:0060297 | inferred from mutant phenotype striated muscle thin filament ; GO:0005865 | inferred from direct assay "CG6771, CG14703, sals, CG31374" IPR003124:WH2 domain CG31374 11-Aug-17 DroID_v2017_08 "Drer\phrf1, Drer\scaf1, Drer\scaf11" Scer\BMT6 - Xtro\rsf1 "Mmus\Phrf1, Mmus\Scaf11, Mmus\Scaf1" "Hsap\PHRF1, Hsap\SCAF11, Hsap\SCAF1" "lethal - all die before end of embryonic stage,some die during embryonic stage,locomotor behavior defective,recessive" "sarcomere,myofibril,striated muscle thin filament" FBgn0083297 E(smoDN)1857 Enhancer of smoDN 1857 http://flybase.org/reports/FBgn0083297 gene - - - E(smoDN)1857 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001164 gv grooved http://flybase.org/reports/FBgn0001164 - gene - - - "gs, gv" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,lethal,recessive" "adult thorax,eye,mesothoracic bristle,adult thorax & trichome" FBgn0261586 CR42696 - http://flybase.org/reports/FBgn0261586 non_protein_coding_gene - - - "CG42696, CR42696" - CR42696 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001592 l(1)carot9 lethal (1) carot9 http://flybase.org/reports/FBgn0001592 - gene - - - l(1)carot9 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003573 su(pr) suppressor of purple http://flybase.org/reports/FBgn0003573 - gene - - - su(pr) - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0030408 CG11085 - http://flybase.org/reports/FBgn0030408 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - CG11085 "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR020479:Homeobox domain, metazoa" CG11085 11-Aug-17 DroID_v2017_08 "Drer\pnx, Drer\barx2, Drer\barhl1b, Drer\nkx1.2lb, Drer\ved, Drer\barhl1a, Drer\tlx3b, Drer\tlx1, Drer\lbx1b, Drer\barx1, Drer\dbx1b, Drer\LOC100008066, Drer\tlx2, Drer\lbx2, Drer\hlx1, Drer\vox, Drer\barhl2, Drer\lbx1a" - "Cele\ceh-31, Cele\ceh-30" "Xtro\barhl2, Xtro\tlx2, Xtro\barx1, Xtro\tlx3, Xtro\tlx1, Xtro\nkx1-1, Xtro\hlx, Xtro\dbx1, Xtro\ventx1.2, Xtro\nkx1-2, Xtro\barhl1" "Mmus\Hlx, Mmus\Barx1, Mmus\Tlx1, Mmus\Lbx2, Mmus\Nkx1-2, Mmus\Dbx1, Mmus\Tlx3, Mmus\Tlx2, Mmus\Nkx1-1, Mmus\Lbx1, Mmus\Barhl2, Mmus\Dbx2, Mmus\Barhl1, Mmus\Barx2" "Hsap\LBX2, Hsap\TLX1, Hsap\NKX1-1, Hsap\BARHL1, Hsap\TLX3, Hsap\DBX1, Hsap\TLX2, Hsap\BARHL2, Hsap\DBX2, Hsap\BARX2, Hsap\HLX, Hsap\BARX1, Hsap\LBX1, Hsap\NKX1-2" viable DRSC22832 K -0.683388551 0.826231749 -0.687523383 0.421765126 -1.534277835 -0.213804046 FBgn0023113 anon-10Au anon-10Au http://flybase.org/reports/FBgn0023113 - gene - - - "14, anon-10Au" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259195 CG42299 - http://flybase.org/reports/FBgn0259195 protein_coding_gene SUMO transferase activity ; GO:0019789 | inferred from electronic annotation with InterPro:IPR026846 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181 double-strand break repair via homologous recombination ; GO:0000724 | inferred from electronic annotation with InterPro:IPR026846 Smc5-Smc6 complex ; GO:0030915 | inferred from electronic annotation with InterPro:IPR026846 "CG42299, CG32584, CG18620, CG15644" "IPR004181:Zinc finger, MIZ-type, IPR026846:E3 SUMO-protein ligase Nse2 (Mms21)" CG42299 11-Aug-17 DroID_v2017_08 Drer\nsmce2 Scer\MMS21 Cele\ZK1248.11 - Mmus\Nsmce2 Hsap\NSMCE2 viable FBgn0042126 CG18788 - http://flybase.org/reports/FBgn0042126 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 CG18788 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG18788 11-Aug-17 DroID_v2017_08 "Drer\slc17a5, Drer\si:ch1073-513e17.1" "Scer\DAL5, Scer\THI73, Scer\YIL166C, Scer\TNA1" "Cele\T10C6.6, Cele\slc-17.5, Cele\slc-17.6, Cele\slc-17.7" - "Mmus\Slc17a1, Mmus\Slc17a2, Mmus\Slc17a4, Mmus\Slc17a3, Mmus\Slc17a5" "Hsap\SLC17A5, Hsap\SLC17A3, Hsap\SLC17A4, Hsap\SLC17A1, Hsap\SLC17A2" viable FBgn0065766 l(2)SH0473 lethal (2) SH0473 http://flybase.org/reports/FBgn0065766 gene - - - "l(2)SH0473, l(2)SH2 0473" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032626 CG12620 - http://flybase.org/reports/FBgn0032626 protein_coding_gene protein phosphatase inhibitor activity ; GO:0004864 | inferred from biological aspect of ancestor with PANTHER:PTN000273866 regulation of signal transduction ; GO:0009966 | inferred from electronic annotation with InterPro:IPR007062 regulation of phosphoprotein phosphatase activity ; GO:0043666 | inferred from biological aspect of ancestor with PANTHER:PTN000273866 protein phosphatase type 1 complex ; GO:0000164 | colocalizes_with inferred from direct assay CG12620 IPR007062:Protein phosphatase inhibitor 2 (IPP-2) CG12620 11-Aug-17 DroID_v2017_08 Drer\ppp1r2 Scer\GLC8 Cele\szy-2 - "Mmus\2810408A11Rik, Mmus\Ppp1r2" Hsap\PPP1R2 "viable,visible" trichogen cell FBgn0039568 CG4815 - http://flybase.org/reports/FBgn0039568 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular space ; GO:0005615 | inferred from direct assay "SP189, CG4815" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG4815 11-Aug-17 DroID_v2017_08 Drer\LOC560023 - "Cele\svh-1, Cele\try-4, Cele\try-5, Cele\try-10, Cele\T22A3.6" - "Mmus\1810009J06Rik, Mmus\Gzmk, Mmus\Try5" "Hsap\PRSS3, Hsap\GZMK" viable FBgn0051217 modSP modular serine protease http://flybase.org/reports/FBgn0051217 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 innate immune response ; GO:0045087 | inferred from direct assay proteolysis ; GO:0006508 | inferred from sequence model" - "SP172, SP53, Ser89E, W, X, CT28389, LDL, CG10100, CG17557, Ldlr, ModSP, Dm-SP, modSP, CG31217" "IPR000436:Sushi/SCR/CCP domain, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR001314:Peptidase S1A, chymotrypsin family" CG31217 11-Aug-17 DroID_v2017_08 "Drer\f9a, Drer\lrp12, Drer\sez6a, Drer\prss12, Drer\lrp3, Drer\f9b, Drer\sez6l2, Drer\masp2, Drer\f10, Drer\LOC100331291, Drer\st14a, Drer\tmprss15, Drer\zgc:154142, Drer\pamr1, Drer\wu:fd46c06, Drer\masp1, Drer\lrp10, Drer\sez6l, Drer\st14b" Scer\APM4 "Cele\fbl-1, Cele\M03E7.4, Cele\rme-2" "Xtro\st14, Xtro\nrp2, Xtro\pamr1, Xtro\lrp10, Xtro\sez6l, Xtro\lrp12" "Mmus\Tmprss15, Mmus\F10, Mmus\Tmprss6, Mmus\Hp, Mmus\C6, Mmus\Pamr1, Mmus\Sez6, Mmus\C1s2, Mmus\Sez6l, Mmus\Sez6l2, Mmus\Lrp3, Mmus\C1s1, Mmus\Masp2, Mmus\C1qtnf5, Mmus\Tmprss7, Mmus\Csmd2, Mmus\Dmbt1, Mmus\St14, Mmus\Masp1, Mmus\C1ra, Mmus\C1rb, Mmus\Lrp10, Mmus\C1rl, Mmus\Lrp12" "Hsap\C1R, Hsap\PROC, Hsap\LRP12, Hsap\TMPRSS6, Hsap\MASP2, Hsap\CSMD2, Hsap\SEZ6L, Hsap\ST14, Hsap\TMPRSS3, Hsap\OVCH1, Hsap\MASP1, Hsap\LRP3, Hsap\TMPRSS15, Hsap\SEZ6L2, Hsap\PAMR1, Hsap\C1RL, Hsap\F10, Hsap\TMPRSS7, Hsap\SEZ6, Hsap\LRP10, Hsap\C1S" "lethal,immune response defective,viable,fertile" FBgn0060955 l(3)S034602b lethal (3) S034602b http://flybase.org/reports/FBgn0060955 gene - - - "0346/02, l(3)S034602b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003107 PL(3)w-S Polygenic locus weight S http://flybase.org/reports/FBgn0003107 - gene - - - "PL(3)w[S], IIIw, PL(3)w-S" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040086 p147 p147 http://flybase.org/reports/FBgn0040086 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available p147 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264889 CR44080 - http://flybase.org/reports/FBgn0264889 non_protein_coding_gene - - - "lincRNA.36, CR44080" - CR44080 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005719 l(1)TK127 lethal (1) TK127 http://flybase.org/reports/FBgn0005719 - gene - - - "l127, l(1)TK127" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0266726 CR45199 - http://flybase.org/reports/FBgn0266726 non_protein_coding_gene - - - CR45199 - CR45199 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040736 IM3 Immune induced molecule 3 http://flybase.org/reports/FBgn0040736 protein_coding_gene molecular_function ; GO:0003674 | no biological data available Toll signaling pathway ; GO:0008063 | non-traceable author statement response to bacterium ; GO:0009617 | inferred from expression pattern antibacterial humoral response ; GO:0019731 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG16844, IM3, CT37419, DIM 3, BcDNA:RH58911, im3" IPR013172:Immune-induced protein Dim CG16844 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030429 CG4661 - http://flybase.org/reports/FBgn0030429 protein_coding_gene - ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR016072 - CG4661 "IPR016072:SKP1 component, dimerisation" CG4661 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032204 CG4953 - http://flybase.org/reports/FBgn0032204 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4953 "IPR010378:Protein of unknown function DUF974, IPR013783:Immunoglobulin-like fold" CG4953 11-Aug-17 DroID_v2017_08 Drer\trappc13 - Cele\C56C10.7 Xtro\trappc13 Mmus\Trappc13 Hsap\TRAPPC13 viable FBgn0267062 CR45506 - http://flybase.org/reports/FBgn0267062 non_protein_coding_gene - - - CR45506 - CR45506 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041593 l(3)HC1 lethal (3) HC1 http://flybase.org/reports/FBgn0041593 gene - - - l(3)HC1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013652 ms(2)ry8 ms(2)ry8 http://flybase.org/reports/FBgn0013652 - gene - - - "ms(2)8, ms(2)ry8" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0013985 Inr-b Inverse regulator b http://flybase.org/reports/FBgn0013985 - gene - - - Inr-b - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" FBgn0060532 l(3)S101003b lethal (3) S101003b http://flybase.org/reports/FBgn0060532 gene - - - "1010/03, l(3)S101003b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069957 CG41061 - http://flybase.org/reports/FBgn0069957 protein_coding_gene - - - CG41061 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002604 M(2)56CD Minute (2) 56CD http://flybase.org/reports/FBgn0002604 - gene - - - "M(2)b, M(2)56CD" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible" "macrochaeta,adult abdomen" FBgn0000184 BicF Bicaudal F http://flybase.org/reports/FBgn0000184 - gene - - - "bicF, BicF" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,dominant,maternal effect" "egg,maternal effect,embryo" FBgn0281844 BG00197 - http://flybase.org/reports/FBgn0281844 gene - - - BG00197 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050055 CR30055 - http://flybase.org/reports/FBgn0050055 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GM14547, CG30055, CR30055" - CR30055 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036873 CG18294 - http://flybase.org/reports/FBgn0036873 protein_coding_gene - - - "BcDNA:RE51966, CG18294" - CG18294 11-Aug-17 DroID_v2017_08 - - - - - - DRSC09891 K -0.969586554 -0.326667177 -0.027300316 0.032241069 -1.529049185 -0.449102247 FBgn0034313 CG5726 - http://flybase.org/reports/FBgn0034313 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay CG5726 - CG5726 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267988 CR46255 - http://flybase.org/reports/FBgn0267988 non_protein_coding_gene - - - CR46255 - CR46255 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266071 CR44824 - http://flybase.org/reports/FBgn0266071 non_protein_coding_gene - - - CR44824 - CR44824 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266163 CG44869 - http://flybase.org/reports/FBgn0266163 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44869 - CG44869 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002951 nofD no object fixation D http://flybase.org/reports/FBgn0002951 - gene - - - nofD - - 11-Aug-17 DroID_v2017_08 - - - - - - adult central nervous system FBgn0052749 CR32749 - http://flybase.org/reports/FBgn0052749 non_protein_coding_gene - - - CR32749 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265703 CR44510 - http://flybase.org/reports/FBgn0265703 non_protein_coding_gene - - - CR44510 - CR44510 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085643 CG41421 - http://flybase.org/reports/FBgn0085643 protein_coding_gene - - - CG41421 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036947 obst-F obstructor-F http://flybase.org/reports/FBgn0036947 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "obst-F, CG7306" IPR002557:Chitin binding domain CG7306 11-Aug-17 DroID_v2017_08 - - "Cele\cbd-1, Cele\R02F2.4, Cele\C39D10.7, Cele\W03F11.1" - - - FBgn0038993 CG13843 - http://flybase.org/reports/FBgn0038993 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13843 - CG13843 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035167 Gr61a Gustatory receptor 61a http://flybase.org/reports/FBgn0035167 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype taste receptor activity ; GO:0008527 | non-traceable author statement detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from electronic annotation with InterPro:IPR009318 sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009318 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr61D1, CG13888, Gr61a, Dmel61a, GR61a" IPR009318:Gustatory receptor CG13888 11-Aug-17 DroID_v2017_08 - - - - - - taste perception defective FBgn0028008 l(3)S114709 lethal (3) S114709 http://flybase.org/reports/FBgn0028008 gene - - - l(3)S114709 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038552 CG18012 - http://flybase.org/reports/FBgn0038552 protein_coding_gene mannosyltransferase activity ; GO:0000030 | inferred from biological aspect of ancestor with PANTHER:PTN000315506 protein glycosylation ; GO:0006486 | inferred from biological aspect of ancestor with PANTHER:PTN000315506 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000315506 "CG18012, Alg1, dAlg1" "IPR028098:Glycosyltransferase subfamily 4-like, N-terminal domain, IPR026051:Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like" CG18012 11-Aug-17 DroID_v2017_08 Drer\alg1 Scer\ALG1 Cele\algn-1 Xtro\alg1 Mmus\Alg1 "Hsap\ALG1L2, Hsap\ALG1, Hsap\ALG1L" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0010085 Ssb Small synaptic boutons http://flybase.org/reports/FBgn0010085 - gene - - synapse ; GO:0045202 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay Ssb - - 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage , oogenesis stage,larval stage , larval stage && spermatogenesis " " abdominal 2--7 ventral acute muscle 3

, abdominal 2--7 ventral acute muscle 2

, abdominal 2--7 ventral longitudinal muscle 1

, somatic muscle

, abdominal 2--7 dorsal acute muscle 3

, abdominal 2--7 dorsal oblique muscle 2

, synapse

, abdominal 2--7 ventral longitudinal muscle 2

, ovary

{ 0 shi* } , abdominal 2--7 segment border muscle

, abdominal 2--7 lateral transverse muscle 2

, abdominal 2--7 ventral oblique muscle 5

, central nervous system

, abdominal 2--7 ventral oblique muscle 1

, abdominal 2--7 dorsal acute muscle 2

, testis

, larval brain | restricted

, abdominal 2--7 ventral acute muscle 1

, abdominal 2--7 ventral oblique muscle 6

, abdominal 2--7 dorsal oblique muscle 1

, abdominal 2--7 dorsal acute muscle 1

, ventral nerve cord

, abdominal 2--7 ventral oblique muscle 4

, abdominal 2--7 ventral oblique muscle 2

, neuropil

" FBgn0037013 CG13250 - http://flybase.org/reports/FBgn0037013 protein_coding_gene - - - CG13250 IPR010512:Protein of unknown function DUF1091 CG13250 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0066326 rux::Dere\rux rux::Dere\rux http://flybase.org/reports/FBgn0066326 engineered_fusion_gene - - - rux::Dere\rux - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030921 CG6290 - http://flybase.org/reports/FBgn0030921 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GH02837, CG6290" - CG6290 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052746 CR32746 - http://flybase.org/reports/FBgn0052746 non_protein_coding_gene - - - CR32746 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003621 Su(var)2-144 Suppressor of variegation 2-144 http://flybase.org/reports/FBgn0003621 - gene - - - Su(var)2-144 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031275 GABA-B-R3 metabotropic GABA-B receptor subtype 3 http://flybase.org/reports/FBgn0031275 protein_coding_gene "G-protein coupled GABA receptor activity ; GO:0004965 | inferred from electronic annotation with InterPro:IPR002455, InterPro:IPR002456 G-protein coupled GABA receptor activity ; GO:0004965 | inferred from sequence or structural similarity" "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000337, InterPro:IPR002455, InterPro:IPR002456, InterPro:IPR017978 sleep ; GO:0030431 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000337, InterPro:IPR002455, InterPro:IPR002456, InterPro:IPR017978 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "GB3, CG3022, D-Gaba3, D-GABA[[B]]R3, anon-WO0170980.14, anon-WO0170980.13, GABA-B-R3, GABA[[B]]R3, GABA[[B]]-R3, GABA B R3, GABA-BR3" "IPR017978:GPCR family 3, C-terminal, IPR000337:GPCR, family 3, IPR001828:Receptor, ligand binding region, IPR002455:GPCR family 3, GABA-B receptor, IPR002456:GPCR family 3, gamma-aminobutyric acid receptor, type B1, IPR028082:Periplasmic binding protein-like I" CG3022 11-Aug-17 DroID_v2017_08 "Drer\gabbr2, Drer\gpr156, Drer\gabbr1a" - "Cele\gbb-2, Cele\gbb-1" "Xtro\gabbr1, Xtro\gabbr2" "Mmus\Gpr156, Mmus\Gabbr2, Mmus\Gabbr1" "Hsap\GABBR1, Hsap\GABBR2, Hsap\GPR156" circadian rhythm defective FBgn0052133 Ptip PAX transcription activation domain interacting protein http://flybase.org/reports/FBgn0052133 protein_coding_gene - "histone methylation ; GO:0016571 | inferred from mutant phenotype regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype anterior/posterior pattern specification, imaginal disc ; GO:0007448 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from direct assay" MLL3/4 complex ; GO:0044666 | inferred from direct assay "CG8797, CG6532, ptip, CG32133, PTIP, Ptip" IPR001357:BRCT domain CG32133 11-Aug-17 DroID_v2017_08 "Drer\mdc1, Drer\paxip1" Scer\RTT107 Cele\pis-1 Xtro\paxip1 "Mmus\Paxip1, Mmus\Mdc1" "Hsap\MDC1, Hsap\PAXIP1" "lethal,recessive,viable,visible" "denticle belt,germline clone,maternal effect,imaginal disc,trichogen cell" DRSC11048 IK -2.816744025 -0.712488958 -0.897331797 0.247900942 1.305952913 2.071406627 FBgn0036676 CG13028 - http://flybase.org/reports/FBgn0036676 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13028, BK002187" - CG13028 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028636 ifm(2)RU6 indirect flight muscle (2) RU6 http://flybase.org/reports/FBgn0028636 gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay ifm(2)RU6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,flight defective,fertile,viable,reduced" "indirect flight muscle,wing,dorsal medial muscle,indirect flight muscle & myofibril" FBgn0014325 l(3)ry50 lethal (3) ry50 http://flybase.org/reports/FBgn0014325 - gene - - - l(3)ry50 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260314 GSd216 - http://flybase.org/reports/FBgn0260314 gene - - - GSd216 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035702 CG10147 - http://flybase.org/reports/FBgn0035702 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG10147 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG10147 11-Aug-17 DroID_v2017_08 "Drer\vezf1b, Drer\znf668, Drer\LOC108183284, Drer\znf1004, Drer\znf1051, Drer\znf1137, Drer\zgc:162948, Drer\zgc:66448, Drer\zgc:171551" - "Cele\blmp-1, Cele\hinf-1, Cele\C04F5.9, Cele\M03D4.4, Cele\klu-1, Cele\Y5F2A.4, Cele\Y48G8AL.10, Cele\sem-4" "Xtro\znf568, Xtro\maz, Xtro\vezf1, Xtro\znf668, Xtro\znf236" "Mmus\Zfp940, Mmus\Zfp647, Mmus\Zfp354a, Mmus\Zim1, Mmus\Maz, Mmus\Zfp87, Mmus\Zfp668, Mmus\Zfp935, Mmus\Zfp961, Mmus\Vezf1" "Hsap\VEZF1, Hsap\ZNF408, Hsap\ZNF668, Hsap\ZNF772, Hsap\MAZ" viable FBgn0065709 l(2)SH0608 lethal (2) SH0608 http://flybase.org/reports/FBgn0065709 gene - - - "l(2)SH0608, l(2)SH2 0608" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053348 CheB42a Chemosensory protein B 42a http://flybase.org/reports/FBgn0053348 protein_coding_gene ion channel binding ; GO:0044325 | inferred from physical interaction with ppk25 lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 channel regulator activity ; GO:0016247 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from mutant phenotype response to pheromone ; GO:0019236 | inferred from mutant phenotype detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from expression pattern protein complex ; GO:0043234 | inferred from physical interaction with ppk25 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "CheB42a, CG15242, CG33348, CheB42A" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG33348 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male " prothoracic tarsal segment 3

, prothoracic tarsal segment 2

, prothoracic tarsal segment

, prothoracic tarsal segment 1

, head

, prothoracic tarsal segment 4

" " pupal stage | late , adult stage | male " prothoracic leg

"mating rhythm defective,taste perception defective,courtship behavior defective,behavior defective,viable" FBgn0031737 obst-E obstructor-E http://flybase.org/reports/FBgn0031737 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "Obst-E, obst-E, CG11142" IPR002557:Chitin binding domain CG11142 11-Aug-17 DroID_v2017_08 - - "Cele\cbd-1, Cele\cpg-2, Cele\dct-9, Cele\R02F2.4" - - - FBgn0013703 mt:tRNA:Gln-TTG mitochondrial transfer RNA:Glutamine-TTG http://flybase.org/reports/FBgn0013703 FBgn0002867 tRNA_gene - - - "CR34061, tRNA[gln], mtdbD00006293, mt:tRNA:Gln-TTG, mt:tRNA:Q, tRNA[Gln]" - CR34061 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031104 jb jean-baptiste http://flybase.org/reports/FBgn0031104 protein_coding_gene molecular_function ; GO:0003674 | no biological data available pupation ; GO:0035074 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG15460, jb" - CG15460 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially lethal - majority live,male limited,some die during pharate adult stage,male fertile" FBgn0029608 CG3091 - http://flybase.org/reports/FBgn0029608 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 CG3091 "IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain, IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport" CG3091 11-Aug-17 DroID_v2017_08 "Drer\rlbp1a, Drer\rlbp1b, Drer\sec14l8, Drer\clvs2, Drer\ttpal, Drer\ttpa, Drer\sec14l7" "Scer\YKL091C, Scer\SEC14, Scer\SFH5" - "Xtro\ttpa, Xtro\sec14l1, Xtro\rlbp1, Xtro\ttpal, Xtro\sec14l3, Xtro\clvs1, Xtro\mospd2, Xtro\sec14l5, Xtro\clvs2" "Mmus\Ttpal, Mmus\Ttpa, Mmus\Clvs1, Mmus\Sec14l1, Mmus\Sec14l4, Mmus\Sec14l3, Mmus\Sec14l2, Mmus\Sec14l5, Mmus\Rlbp1, Mmus\Clvs2" "Hsap\SEC14L4, Hsap\SEC14L2, Hsap\TTPAL, Hsap\RLBP1, Hsap\SEC14L1, Hsap\CLVS1, Hsap\TTPA, Hsap\SEC14L3, Hsap\SEC14L5, Hsap\CLVS2, Hsap\SEC14L6" viable DRSC18274 I 1.802697402 0.841848078 0.061033382 0.116129833 0.553833087 -0.16742402 FBgn0001364 l(1)1Fc lethal (1) 1Fc http://flybase.org/reports/FBgn0001364 - gene - - - "l(1)1Fc, JA29" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0267993 CR46260 - http://flybase.org/reports/FBgn0267993 non_protein_coding_gene - - - CR46260 - CR46260 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267168 CR45608 - http://flybase.org/reports/FBgn0267168 non_protein_coding_gene - - - CR45608 - CR45608 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266832 CR45294 - http://flybase.org/reports/FBgn0266832 non_protein_coding_gene - - - CR45294 - CR45294 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052708 CG32708 - http://flybase.org/reports/FBgn0052708 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000472 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000480 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 small-subunit processome assembly ; GO:0034462 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 "CG6997, CG32708" "IPR034353:ABT1/ESF2, RNA recognition motif, IPR000504:RNA recognition motif domain" CG32708 11-Aug-17 DroID_v2017_08 Drer\abt1 Scer\ESF2 Cele\F57B10.8 Xtro\abt1 Mmus\Abt1 Hsap\ABT1 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0005063 fs(2)OW203 female sterile (2) OW203 http://flybase.org/reports/FBgn0005063 - gene - - - fs(2)OW203 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067737 l(1)G0352 lethal (1) G0352 http://flybase.org/reports/FBgn0067737 gene - - - l(1)G0352 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0040167 l(1)G0376 lethal (1) G0376 http://flybase.org/reports/FBgn0040167 gene - - - l(1)G0376 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0034420 CG10737 - http://flybase.org/reports/FBgn0034420 protein_coding_gene - intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 - "10737, CG10737" "IPR000008:C2 domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain" CG10737 11-Aug-17 DroID_v2017_08 "Drer\c2cd2, Drer\c2cd2l" - Cele\R11G1.6 - "Mmus\Prkch, Mmus\C2cd2, Mmus\C2cd2l" "Hsap\PRKCH, Hsap\C2CD2, Hsap\C2CD2L" "viable,visible" trichogen cell FBgn0265894 CR44683 - http://flybase.org/reports/FBgn0265894 non_protein_coding_gene - - - "CR44683, lincRNA.633" - CR44683 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002350 l(3)87Db lethal (3) 87Db http://flybase.org/reports/FBgn0002350 - gene - - - "0091/13, l(3)S5, S5, l(3)87Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065812 l(2)SH0383 lethal (2) SH0383 http://flybase.org/reports/FBgn0065812 gene - - - "l(2)SH0383, l(2)SH2 0383" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060298 p69 p69 http://flybase.org/reports/FBgn0060298 gene SH2 domain binding ; GO:0042169 | inferred from direct assay - - p69 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031189 CG14618 - http://flybase.org/reports/FBgn0031189 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR016653 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14618 "IPR007356:tRNA (guanine-N1-)-methyltransferase, eukaryotic, IPR016009:tRNA methyltransferase TRMD/TRM10-type domain, IPR016653:tRNA (guanine(9)-N(1))-methyltransferase TRM10, IPR028564:tRNA methyltransferase TRM10-type domain" CG14618 11-Aug-17 DroID_v2017_08 "Drer\trmt10b, Drer\trmt10a, Drer\trmt10c" Scer\TRM10 "Cele\F46F11.10, Cele\F25H8.1, Cele\C56G2.3" "Xtro\trmt10a, Xtro\trmt10c" "Mmus\Trmt10b, Mmus\Trmt10c, Mmus\Trmt10a" "Hsap\TRMT10A, Hsap\TRMT10C, Hsap\TRMT10B" "viable,fertile" FBgn0033447 dila dilatory http://flybase.org/reports/FBgn0033447 protein_coding_gene - intraciliary transport involved in cilium assembly ; GO:0035735 | inferred from electronic annotation with InterPro:IPR030465 spermatogenesis ; GO:0007283 | inferred from mutant phenotype intraciliary transport ; GO:0042073 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from genetic interaction with Cby cilium assembly ; GO:0060271 | inferred from mutant phenotype axoneme assembly ; GO:0035082 | inferred from mutant phenotype protein localization to ciliary transition zone ; GO:1904491 | inferred from genetic interaction with Cby peripheral nervous system neuron development ; GO:0048935 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from genetic interaction with Cby regulation of centrosome duplication ; GO:0010824 | inferred from biological aspect of ancestor with PANTHER:PTN001267958 ciliary transition zone assembly ; GO:1905349 | inferred from genetic interaction with Cby ciliary basal body docking ; GO:0097711 | inferred from genetic interaction with Cby ciliary transition zone ; GO:0035869 | inferred from direct assay ciliary basal body ; GO:0036064 | inferred from direct assay centriolar satellite ; GO:0034451 | inferred from biological aspect of ancestor with PANTHER:PTN001267958 pericentriolar material ; GO:0000242 | inferred from direct assay "CG1625, CG1626, dila" IPR030465:Centrosomal protein of 131 kDa CG1625 11-Aug-17 DroID_v2017_08 Drer\cep131 Scer\ZIP1 - Xtro\cep131 Mmus\Cep131 Hsap\CEP131 "viable,uncoordinated,recessive,bang sensitive,short lived,male semi-sterile" "cilium,axonemal microtubule,axonemal dynein complex,spermatozoon,microtubule-based flagellum" FBgn0000718 Forkoid Forkoid http://flybase.org/reports/FBgn0000718 - gene - - - "Forkoid, Fo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" "head bristle,macrochaeta & adult thorax | posterior,macrochaeta" FBgn0025734 sca::Hsap\FGA sca::Hsap\FGA http://flybase.org/reports/FBgn0025734 - engineered_fusion_gene - - - sca::Hsap\FGA - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein" FBgn0041152 grim::rpr grim::rpr http://flybase.org/reports/FBgn0041152 engineered_fusion_gene - - - grim::rpr - - 11-Aug-17 DroID_v2017_08 - - - - - - "increased cell death,lethal,visible,heat sensitive,eye color defective" "midline glial cell,eye,pigment cell,ommatidium,heat sensitive" FBgn0264603 CR43952 - http://flybase.org/reports/FBgn0264603 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43952, CR43952" - CR43952 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015364 anon-topo anon-topoisomerase II cleavage sites http://flybase.org/reports/FBgn0015364 - region - - - anon-topo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033051 Strica Ser/Thr-rich caspase http://flybase.org/reports/FBgn0033051 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | non-traceable author statement cysteine-type endopeptidase activity involved in apoptotic process ; GO:0097153 | inferred from biological aspect of ancestor with PANTHER:PTN000047947 cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement "larval midgut histolysis ; GO:0035069 | inferred from electronic annotation with InterPro:IPR033176 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001309, InterPro:IPR002138, InterPro:IPR011600 salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype positive regulation of compound eye retinal cell programmed cell death ; GO:0046672 | inferred from mutant phenotype programmed cell death ; GO:0012501 | inferred from direct assay programmed cell death ; GO:0012501 | traceable author statement nurse cell apoptotic process ; GO:0045476 | inferred from genetic interaction with Dronc" cytoplasm ; GO:0005737 | inferred from direct assay "strica, CG7863, Strica/Dream, STRICA, STRICA/DREAM, Strica, Dream/Strica, Dream, DREAM, dream" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR015917:Peptidase C14A, caspase catalytic domain, IPR033176:Caspase DECAY, IPR029030:Caspase-like domain" CG7863 11-Aug-17 DroID_v2017_08 "Drer\cflara, Drer\zgc:171731, Drer\casp6, Drer\caspxa, Drer\pea15, Drer\casp2, Drer\caspbl, Drer\casp8l2, Drer\casp9, Drer\casp6l1, Drer\caspa, Drer\casp8l1, Drer\LOC100331324, Drer\casp3b, Drer\casp6l2, Drer\gbp3, Drer\LOC798445, Drer\caspb, Drer\casp3a, Drer\casp8, Drer\si:ch211-195h23.3, Drer\LOC101886133, Drer\casp7" - Cele\ced-3 "Xtro\casp1, Xtro\casp7, Xtro\casp10, Xtro\casp6, Xtro\casp2, Xtro\casp3, Xtro\LOC733553, Xtro\casp9, Xtro\pea15" "Mmus\Casp1, Mmus\Cflar, Mmus\Casp4, Mmus\Casp7, Mmus\Pea15a, Mmus\Casp6, Mmus\Casp14, Mmus\Pycard, Mmus\Casp9, Mmus\Casp8, Mmus\Casp12, Mmus\Casp3, Mmus\Casp2" "Hsap\PYCARD, Hsap\CASP2, Hsap\CASP7, Hsap\CASP10, Hsap\CARD16, Hsap\CASP5, Hsap\CASP3, Hsap\CASP14, Hsap\CARD18, Hsap\CFLAR, Hsap\PEA15, Hsap\CASP1, Hsap\CARD8, Hsap\CASP8, Hsap\CARD17, Hsap\CASP9, Hsap\CASP6, Hsap\CASP4" pupal stage salivary gland

"decreased cell death,neuroanatomy defective,viable,fertile,visible,cell death defective" "peptidergic neuron,ectopic,eye,inter-ommatidial precursor cell,supernumerary,salivary gland | pupal stage,egg chamber" FBgn0013300 ProtA Protamine A http://flybase.org/reports/FBgn0013300 "FBgn0010308, FBgn0063695" protein_coding_gene DNA binding ; GO:0003677 | inferred from sequence or structural similarity "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from direct assay sperm chromatin condensation ; GO:0035092 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype inferred from genetic interaction with ProtB" chromatin ; GO:0000785 | inferred from direct assay "BG:DS03431.2, mst35b, CG4479, BcDNA:AT31403, Mst35Ba, ProtA, mst35B, protA, dProtA, mst35Ba, MST35Ba" "IPR009071:High mobility group box domain, IPR024460:Protamine-like" CG4479 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266138 CR44844 - http://flybase.org/reports/FBgn0266138 non_protein_coding_gene - - - CR44844 - CR44844 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037667 CG16734 - http://flybase.org/reports/FBgn0037667 protein_coding_gene - - - CG16734 - CG16734 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0027306 l(1)G0116 lethal (1) G0116 http://flybase.org/reports/FBgn0027306 - gene - - - l(1)G0116 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0058376 CG40376 - http://flybase.org/reports/FBgn0058376 protein_coding_gene - - - CG40376 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027291 l(1)G0156 lethal (1) G0156 http://flybase.org/reports/FBgn0027291 FBgn0031024 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR019818 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR019818 isocitrate dehydrogenase (NAD+) activity ; GO:0004449 | inferred from sequence or structural similarity with UniProtKB:P50213 isocitrate dehydrogenase (NAD+) activity ; GO:0004449 | inferred from sequence or structural similarity with UniProtKB:P56471" tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P56471 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P50213 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P50213 lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P56471 "CG12233, FBgn0031024, l(1)G0156, l (1) G0156" "IPR004434:Isocitrate dehydrogenase NAD-dependent, IPR019818:Isocitrate/isopropylmalate dehydrogenase, conserved site, IPR024084:Isopropylmalate dehydrogenase-like domain" CG12233 11-Aug-17 DroID_v2017_08 "Drer\idh3a, Drer\idh3b" "Scer\IDH2, Scer\LEU2, Scer\LYS12" "Cele\idhg-2, Cele\idha-1" "Xtro\idh3a, Xtro\idh3b, Xtro\idh3g" "Mmus\4933405O20Rik, Mmus\Idh3a, Mmus\Idh3g, Mmus\Idh3b" "Hsap\IDH3A, Hsap\IDH3B, Hsap\IDH3G" "viable,fertile,lethal,recessive,visible" trichogen cell FBgn0259455 C411 - http://flybase.org/reports/FBgn0259455 gene - - - C411 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing hair FBgn0037178 CG12546 - http://flybase.org/reports/FBgn0037178 protein_coding_gene - - - "BcDNA:RE45259, CG12546" - CG12546 11-Aug-17 DroID_v2017_08 - - - - - - DRSC11676 EK 0.511186168 -0.009471605 0.397126188 -1.520763728 -1.796128582 -0.606801452 FBgn0039628 CG11841 - http://flybase.org/reports/FBgn0039628 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP45, BcDNA:GH26583, anon-WO0140519.6, anon-WO0140519.18, CG11841" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11841 11-Aug-17 DroID_v2017_08 - - "Cele\svh-1, Cele\try-1" - "Mmus\Plau, Mmus\Plat, Mmus\Habp2, Mmus\F12, Mmus\Prss12, Mmus\Hgfac" - "partially lethal - majority die,some die during pupal stage" FBgn0026618 verfilzt verfilzt http://flybase.org/reports/FBgn0026618 - gene - - - verfilzt - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic/larval central nervous system,commissure" FBgn0000710 Flutter Flutter http://flybase.org/reports/FBgn0000710 - gene - - - "Flu, Flutter" - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,semidominant,behavior defective,recessive,dominant" "dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle" FBgn0263958 BG01403 - http://flybase.org/reports/FBgn0263958 gene - - - BG01403 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,starvation stress response defective,male limited,temperature response defective" FBgn0067050 Rst(2)DDT-WIS1 Resistant to DDT on II Wisconsin 1 http://flybase.org/reports/FBgn0067050 gene - response to DDT ; GO:0046680 | inferred from mutant phenotype response to insecticide ; GO:0017085 | inferred from mutant phenotype response to organophosphorus ; GO:0046683 | inferred from mutant phenotype - "Rst(2)DDT, Rst(2)DDT-WIS1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0031285 CG3662 - http://flybase.org/reports/FBgn0031285 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG3662 IPR007084:BRICHOS domain CG3662 11-Aug-17 DroID_v2017_08 "Drer\itm2ca, Drer\itm2cb, Drer\itm2bb, Drer\itm2ba" - Cele\C25F6.7 "Xtro\itm2b, Xtro\itm2a" "Mmus\Itm2b, Mmus\Itm2c, Mmus\Itm2a" "Hsap\ITM2B, Hsap\ITM2C, Hsap\ITM2A" "viable,fertile" FBgn0261967 huc2L-16 hydroxyurea- and (or) caffeine-sensitive 2L-16 http://flybase.org/reports/FBgn0261967 gene - - - "huc2L-16, huc[2L-16]" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,somatic clone,partially lethal - majority live" "eye,somatic clone,drug conditional" FBgn0260231 CG42505 - http://flybase.org/reports/FBgn0260231 protein_coding_gene - - - CG42505 - CG42505 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035812 CG7457 - http://flybase.org/reports/FBgn0035812 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT13960, CG7457" "IPR002110:Ankyrin repeat, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR019734:Tetratricopeptide repeat, IPR020683:Ankyrin repeat-containing domain, IPR001611:Leucine-rich repeat" CG7457 11-Aug-17 DroID_v2017_08 "Drer\tonsl, Drer\bard1" Scer\HOS4 "Cele\T16G1.9, Cele\K02B12.5, Cele\ags-3" Xtro\tonsl "Mmus\Tonsl, Mmus\Bard1, Mmus\Slf1" "Hsap\TONSL, Hsap\SLF1, Hsap\BARD1" viable FBgn0014245 l(2)32Af lethal (2) 32Af http://flybase.org/reports/FBgn0014245 - gene - - - l(2)32Af - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266578 CR45109 - http://flybase.org/reports/FBgn0266578 non_protein_coding_gene - - - CR45109 - CR45109 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267146 CR45586 - http://flybase.org/reports/FBgn0267146 non_protein_coding_gene - - - CR45586 - CR45586 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031442 Prosbeta4R1 Proteasome beta4 subunit-related 1 http://flybase.org/reports/FBgn0031442 protein_coding_gene threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353 molecular_function ; GO:0003674 | no biological data available "proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR016050" "proteasome core complex ; GO:0005839 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR016050" "BcDNA:AT30033, CG17301, Prosbeta4R1, beta4R1" "IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR029055:Nucleophile aminohydrolases, N-terminal" CG17301 11-Aug-17 DroID_v2017_08 Drer\psmb2 Scer\PRE1 Cele\pbs-4 Xtro\psmb2 Mmus\Psmb2 Hsap\PSMB2 viable FBgn0003233 ref(3)O refractory to sigma O http://flybase.org/reports/FBgn0003233 - gene - - - ref(3)O - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035439 CG14961 - http://flybase.org/reports/FBgn0035439 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14961 - CG14961 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0040285 Scamp Scamp http://flybase.org/reports/FBgn0040285 protein_coding_gene - protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR007273 locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity neuromuscular synaptic transmission ; GO:0007274 | inferred from genetic interaction with be long-term memory ; GO:0007616 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from genetic interaction with be integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007273 synaptic vesicle ; GO:0008021 | non-traceable author statement axon ; GO:0030424 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay "dmSC, CG9195, SCAMP, dmSCAMP, anon-EST:fe1F7, BcDNA:GM04934, Scamp, Sc" IPR007273:SCAMP CG9195 11-Aug-17 DroID_v2017_08 "Drer\scamp4, Drer\scamp3, Drer\scamp2, Drer\scamp5a, Drer\scamp1, Drer\scamp5b, Drer\scamp2l" - Cele\scm-1 "Xtro\scamp2, Xtro\scamp3, Xtro\scamp1, Xtro\scamp5" "Mmus\Scamp2, Mmus\Scamp3, Mmus\Scamp5, Mmus\Scamp4, Mmus\Scamp1" "Hsap\SCAMP3, Hsap\SCAMP4, Hsap\SCAMP1, Hsap\SCAMP2, Hsap\SCAMP5" viable DRSC20286 I 1.768355394 -0.45673758 0.063663516 0.305190159 1.165449423 -0.070402274 FBgn0263550 mir-4918 mir-4918 stem loop http://flybase.org/reports/FBgn0263550 miRNA_gene - - - "mir-4918, dme-mir-4918, CR43535" - CR43535 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024531 l(3)L0539 lethal (3) L0539 http://flybase.org/reports/FBgn0024531 - gene - - - "EP(3)3083, l(3)L0539" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,lethal - all die before end of P-stage,some die during pharate adult stage" "eye,wing" FBgn0053293 CG33293 - http://flybase.org/reports/FBgn0053293 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs35d06.y1, bs34a01.y1, bs06b05.y1, bs07d08.y1, NEST:bs34a01, NEST:bs06b05, NEST:bs35d06, BcDNA:GH07964, CG12163, NEST:bs07d08, CG33293" - CG33293 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084480 fz::wntD fz::wntD http://flybase.org/reports/FBgn0084480 engineered_fusion_gene - - - fz::wntD - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084819 l(3)S026238 l(3)S026238 http://flybase.org/reports/FBgn0084819 gene - - - l(3)S026238 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052719 CG32719 - http://flybase.org/reports/FBgn0052719 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32719 IPR031732:Protein of unknown function DUF4729 CG32719 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262696 Su(VGlut)B36 - http://flybase.org/reports/FBgn0262696 gene - - - "Su(VGlut)B36, B36" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029660 CG10801 - http://flybase.org/reports/FBgn0029660 protein_coding_gene - - - CG10801 "IPR011705:BTB/Kelch-associated, IPR031750:Domain of unknown function DUF4734" CG10801 11-Aug-17 DroID_v2017_08 Drer\klhl41a - Cele\kel-3 - - - viable FBgn0026642 l(2)k08401a lethal (2) k08401a http://flybase.org/reports/FBgn0026642 - gene - - - "l(2)k08401, l(2)k08401a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015855 anon-12Eb anon-12Eb http://flybase.org/reports/FBgn0015855 - gene - - - anon-12Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011132 l(1)Q206 lethal (1) Q206 http://flybase.org/reports/FBgn0011132 FBgn0010210 gene - - - l(1)Q206 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058336 CG40336 - http://flybase.org/reports/FBgn0058336 protein_coding_gene - - - CG40336 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035461 ntc nutcracker http://flybase.org/reports/FBgn0035461 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model sperm individualization ; GO:0007291 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay "ntc, CG10855, nutcracker, FBXO7" IPR001810:F-box domain CG10855 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,male sterile,sterile" "individualization stage spermatid,cystic bulge,sperm individualization complex" FBgn0267004 CR45448 - http://flybase.org/reports/FBgn0267004 non_protein_coding_gene - - - CR45448 - CR45448 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031661 Gmd "GDP-mannose 4,6-dehydratase" http://flybase.org/reports/FBgn0031661 protein_coding_gene "GDP-mannose 4,6-dehydratase activity ; GO:0008446 | inferred from direct assay" GDP-mannose metabolic process ; GO:0019673 | inferred from electronic annotation with InterPro:IPR006368 Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype GDP-L-fucose biosynthetic process ; GO:0042350 | inferred from direct assay oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of stem cell division ; GO:2000035 | inferred from mutant phenotype - "Dm-gmd, CG8890, l(2)SH1606, Gmd, l(2)SH2 1606, gmd, GMD, DmGMD, Brazil nut" "IPR006368:GDP-mannose 4,6-dehydratase, IPR016040:NAD(P)-binding domain" CG8890 11-Aug-17 DroID_v2017_08 Drer\gmds - "Cele\gmd-2, Cele\bre-1" Xtro\gmds Mmus\Gmds Hsap\GMDS "lethal,recessive,visible,conditional,size defective,viable,fertile,germline clone,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "eye disc,eye,conditional,wing,egg chamber,somatic clone,oocyte associated follicular epithelium,follicle cell,wing disc,intestinal stem cell,supernumerary" FBgn0265051 CR44166 - http://flybase.org/reports/FBgn0265051 non_protein_coding_gene - - - CR44166 - CR44166 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031848 Nse1 Non-SMC element 1 http://flybase.org/reports/FBgn0031848 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000003997 ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN000469404 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:29897 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with UniProtKB:Q8WV22 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:29897 protein ubiquitination ; GO:0016567 | inferred from biological aspect of ancestor with PANTHER:PTN000469404 postreplication repair ; GO:0006301 | inferred from biological aspect of ancestor with PANTHER:PTN000469404 double-strand break repair via homologous recombination ; GO:0000724 | inferred from biological aspect of ancestor with PANTHER:PTN000469404 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000003997 positive regulation of response to DNA damage stimulus ; GO:2001022 | inferred from sequence or structural similarity with UniProtKB:Q8WV22 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000003997 Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with UniProtKB:Q8WV22 Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with HGNC:29897 Smc5-Smc6 complex ; GO:0030915 | inferred from biological aspect of ancestor with PANTHER:PTN000469404 Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000003997 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000469404 "EST2, GM14348, anon-WO0118547.82, NSE1, Nse1, CG11329" "IPR011513:Non-structural maintenance of chromosomes element 1, IPR014857:Zinc finger, RING-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11329 11-Aug-17 DroID_v2017_08 Drer\nsmce1 Scer\NSE1 Cele\T27A3.7 Xtro\nsmce1 Mmus\Nsmce1 Hsap\NSMCE1 viable FBgn0029114 Tollo Tollo http://flybase.org/reports/FBgn0029114 protein_coding_gene - "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000157 regulation of protein glycosylation ; GO:0060049 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype axis elongation ; GO:0003401 | inferred from genetic interaction with 18w, Toll-6 convergent extension ; GO:0060026 | inferred from genetic interaction with 18w, Toll-6 peripheral nervous system neuron development ; GO:0048935 | inferred from mutant phenotype innate immune response in mucosa ; GO:0002227 | inferred from mutant phenotype" - "dToll8, tollo, Toll-8, toll, CG6890, dTLR8, Tl-8, CT21344, Tollo, tollo/toll-8, TOLL 8" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5" CG6890 11-Aug-17 DroID_v2017_08 "Drer\tlr7, Drer\chadla, Drer\LOC572462, Drer\tlr8b, Drer\LOC100332583, Drer\tlr5a, Drer\tlr3, Drer\tlr1, Drer\chad, Drer\chadlb, Drer\tlr20.2, Drer\si:dkey-182i3.11, Drer\zgc:101569, Drer\LOC100332783, Drer\LOC100005571, Drer\tlr2, Drer\tlr18, Drer\cd180, Drer\tlr4ba, Drer\tlr21, Drer\lrriq1, Drer\tlr5b, Drer\tlr9, Drer\tlr4bb" - "Cele\lron-2, Cele\lron-1, Cele\tol-1, Cele\pan-1, Cele\lron-9" "Xtro\tlr6, Xtro\tlr5, Xtro\LOC100488097, Xtro\LOC100495326, Xtro\tlr7, Xtro\LOC100485201, Xtro\tlr9, Xtro\chadl, Xtro\LOC100485512, Xtro\tlr3, Xtro\tlr2, Xtro\LOC100485164, Xtro\LOC100485706" "Mmus\Tlr12, Mmus\Tlr9, Mmus\Tlr8, Mmus\Nrros, Mmus\Tlr13, Mmus\Vasn, Mmus\Tlr7, Mmus\Tlr3, Mmus\Tlr5, Mmus\Tlr6, Mmus\Tlr1, Mmus\Cd180, Mmus\Tlr4, Mmus\Tlr2, Mmus\Chadl, Mmus\Chad" "Hsap\TLR10, Hsap\TLR7, Hsap\TLR4, Hsap\TLR9, Hsap\TLR2, Hsap\CHAD, Hsap\TLR3, Hsap\CHADL, Hsap\VASN, Hsap\TLR5, Hsap\TLR6, Hsap\NRROS, Hsap\TLR1, Hsap\CD180, Hsap\TLR8" embryonic stage -- adult stage "lethal,viable,fertile,partially lethal - majority live,visible,cold sensitive,dominant" "adult abdomen,macrochaeta,ectopic,eye,wing vein,leg,wing,wing disc,ventral thoracic disc,tibia,tarsal segment,femur,cold sensitive,mesothoracic tergum,wing pouch,somatic clone" FBgn0027970 l(3)S142916 lethal (3) S142916 http://flybase.org/reports/FBgn0027970 gene - - - "1429/16, 1400/09, 0925/01, 0510/01, l(3)S142916" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082943 snoRNA:Me28S-A982a snoRNA:Me28S-A982a http://flybase.org/reports/FBgn0082943 snoRNA_gene - - - "snoRNA:Me28S-A982a, Me28S-Am982a, Me28S-A982a(DmSnR39/59), CR34527, DmSnR39/59a" - CR34527 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001163 GustR Gustatory R http://flybase.org/reports/FBgn0001163 - gene - - - GustR - - 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,dominant" taste bristle FBgn0016825 l(1)MZ12 lethal (1) MZ12 http://flybase.org/reports/FBgn0016825 - gene - - - "l(1)MZ12, M12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259223 CG42323 - http://flybase.org/reports/FBgn0259223 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42323, CG15055, CG32550" - CG42323 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259200 CG42304 - http://flybase.org/reports/FBgn0259200 protein_coding_gene - - - "CG42304, CG1248, CG32297" IPR026064:Terminal deoxynucleotidyltransferase-interacting factor 1 CG42304 11-Aug-17 DroID_v2017_08 Drer\dnttip1 - Cele\saeg-2 Xtro\dnttip1 Mmus\Dnttip1 Hsap\DNTTIP1 DRSC08277 E 1.407295649 0.264927075 1.554187307 0.009826797 0.957795885 -0.795477802 FBgn0050269 CG30269 - http://flybase.org/reports/FBgn0050269 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13515, CG30269" IPR006629:LPS-induced tumour necrosis factor alpha factor CG30269 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-202h22.9, Drer\litaf, Drer\cdip1, Drer\si:ch211-202h22.7, Drer\si:ch211-202h22.8, Drer\si:ch211-157c3.4, Drer\si:dkeyp-75b4.8" - "Cele\C08E8.1, Cele\Y37D8A.8, Cele\Y40H7A.11, Cele\Y22D7AL.15, Cele\F36G3.3, Cele\Y87G2A.18, Cele\Y87G2A.19, Cele\F16F9.1, Cele\Y37D8A.26, Cele\B0348.1, Cele\B0348.2, Cele\Y37D8A.6" Xtro\litaf "Mmus\Cdip1, Mmus\Litaf" "Hsap\LITAF, Hsap\CDIP1" "viable,visible" trichogen cell FBgn0031752 CG9044 - http://flybase.org/reports/FBgn0031752 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from sequence or structural similarity with HGNC:19184 protein localization ; GO:0008104 | inferred from sequence or structural similarity with HGNC:19184 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:19184 "CT25972, CG9044, mdcds_8484" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR031782:LKB1 serine/threonine kinase interacting protein 1, N-terminal" CG9044 11-Aug-17 DroID_v2017_08 "Drer\nisch, Drer\stk11ip" - Cele\F13E9.1 Xtro\stk11ip "Mmus\Nisch, Mmus\Stk11ip" "Hsap\NISCH, Hsap\STK11IP" viable FBgn0024285 Srp54 Srp54 http://flybase.org/reports/FBgn0024285 FBgn0025965 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with HGNC:11301 poly-pyrimidine tract binding ; GO:0008187 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from direct assay "photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype regulation of transcriptional start site selection at RNA polymerase II promoter ; GO:0001178 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with HGNC:11301 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype regulation of mRNA 3'-end processing ; GO:0031440 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "SRp54, CG4602, p75, dSRp54, clone 2.16, anon-EST:Liang-2.16, Srp54, SRP54, srp54" "IPR000504:RNA recognition motif domain, IPR034192:SREK1, RNA recognition motif 2" CG4602 11-Aug-17 DroID_v2017_08 "Drer\srsf11, Drer\srek1" - Cele\rsp-7 Xtro\srek1 "Mmus\Srek1, Mmus\Srsf11" "Hsap\SREK1, Hsap\SRSF11" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC03442 IK -1.848458329 -1.322251605 -0.028225757 0.025790837 2.231589329 1.590925595 FBgn0041722 rsh rsh http://flybase.org/reports/FBgn0041722 gene molecular_function ; GO:0003674 | no biological data available defense response ; GO:0006952 | inferred from mutant phenotype response to bacterium ; GO:0009617 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available rsh - - 11-Aug-17 DroID_v2017_08 - - - - - - immune response defective FBgn0036810 CG6885 - http://flybase.org/reports/FBgn0036810 protein_coding_gene - - - "anon-WO0118547.731, CG6885" - CG6885 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC10740 I 1.968592489 0.206287051 -0.902799763 -0.107821366 1.451330245 0.601961836 FBgn0001561 l(1)19Ed lethal (1) 19Ed http://flybase.org/reports/FBgn0001561 "FBgn0001731, FBgn0011263, FBgn0011264" gene - - - "D83, D76, EC235, l(1)EC235, HM-435, l(1)ESHS52, l(1)19Ed" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" FBgn0026143 CDC45L CDC45L http://flybase.org/reports/FBgn0026143 FBgn0014904 protein_coding_gene 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000053416 DNA replication origin binding ; GO:0003688 | inferred from biological aspect of ancestor with PANTHER:PTN000053416 chromatin binding ; GO:0003682 | inferred from direct assay chromosome condensation ; GO:0030261 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from sequence or structural similarity with HGNC:1739 inferred from sequence or structural similarity with SGD:S000004093 DNA replication initiation ; GO:0006270 | inferred from biological aspect of ancestor with PANTHER:PTN000053416 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype DNA amplification ; GO:0006277 | inferred from expression pattern mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype inferred from genetic interaction with nbs neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of chromatin silencing at telomere ; GO:0031938 | inferred from biological aspect of ancestor with PANTHER:PTN000053416 pre-replicative complex assembly involved in nuclear cell cycle DNA replication ; GO:0006267 | inferred from biological aspect of ancestor with PANTHER:PTN000053416 mitotic DNA replication preinitiation complex assembly ; GO:1902977 | inferred from biological aspect of ancestor with PANTHER:PTN000053416 double-strand break repair via break-induced replication ; GO:0000727 | inferred from biological aspect of ancestor with PANTHER:PTN000053416 DNA replication ; GO:0006260 | inferred from physical interaction with dpa inferred from physical interaction with Mcm5 positive regulation of G1/S transition of mitotic cell cycle ; GO:1900087 | inferred from mutant phenotype nuclear pre-replicative complex ; GO:0005656 | inferred from sequence or structural similarity with HGNC:1739 inferred from sequence or structural similarity with SGD:S000004093 inferred from physical interaction with dpa inferred from physical interaction with Mcm5 cytoplasm ; GO:0005737 | inferred from direct assay replication fork protection complex ; GO:0031298 | inferred from biological aspect of ancestor with PANTHER:PTN000053416 nucleus ; GO:0005634 | inferred from direct assay DNA replication preinitiation complex ; GO:0031261 | inferred from biological aspect of ancestor with PANTHER:PTN000053416 "CDC45, Cdc45, CG3658, EG:BACR7A4.11, DmCdc45, D, anon-1Ec, CDC45L, dCDC45, cdc45, dCDC45L" IPR003874:CDC45 family CG3658 11-Aug-17 DroID_v2017_08 Drer\cdc45 Scer\CDC45 "Cele\evl-18, Cele\F34D10.9" Xtro\cdc45 Mmus\Cdc45 Hsap\CDC45 "lethal,some die during first instar larval stage,some die during second instar larval stage,radiation sensitive,neuroanatomy defective,viable,visible" "nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC17747 K -0.349668511 -1.40806763 -0.562534643 0.439386108 1.74261631 1.119926918 FBgn0027661 anon-H15 anon-H15 http://flybase.org/reports/FBgn0027661 - gene - - - "DMH#15, anon-H15" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028091 l(3)S081003 lethal (3) S081003 http://flybase.org/reports/FBgn0028091 gene - - - "l(3)S145911, 1473/10, 1472/07, 1459/11, 1225/01, 1199/06, 0810/03, 0770/08, 0693/07, 0528/04, 0073/29, l(3)S081003" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" FBgn0035631 Txl Thioredoxin-like http://flybase.org/reports/FBgn0035631 protein_coding_gene "protein disulfide oxidoreductase activity ; GO:0015035 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 protein-disulfide reductase activity ; GO:0047134 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 thioredoxin-disulfide reductase activity ; GO:0004791 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ; GO:0016671 | inferred from biological aspect of ancestor with PANTHER:PTN000047179" cellular response to oxidative stress ; GO:0034599 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 cell redox homeostasis ; GO:0045454 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 "txl, CG5495, anon-WO0118547.248, Txl, 5495" "IPR010400:PITH domain, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site, IPR008979:Galactose-binding domain-like" CG5495 11-Aug-17 DroID_v2017_08 "Drer\txn, Drer\txnl1, Drer\zgc:56493" "Scer\TRX2, Scer\TRX1" "Cele\txl-1, Cele\Y55F3AR.2, Cele\W01B11.6, Cele\png-1" "Xtro\LOC100170420, Xtro\txn, Xtro\txnl1" "Mmus\Txnl1, Mmus\Txn1" "Hsap\TXNL1, Hsap\TXN" "viable,body color defective" mesothoracic tergum FBgn0264272 mwh multiple wing hairs http://flybase.org/reports/FBgn0264272 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR010472 Rho GTPase binding ; GO:0017048 | inferred from electronic annotation with InterPro:IPR010473 protein binding ; GO:0005515 | inferred from physical interaction with cmb imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype imaginal disc-derived wing hair site selection ; GO:0035320 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of actin filament polymerization ; GO:0030837 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | traceable author statement cellular_component ; GO:0005575 | no biological data available "mwh, CG43772, CG13913, BP1018, CG34022" "IPR011989:Armadillo-like helical, IPR010472:Formin, FH3 domain, IPR014768:Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR016024:Armadillo-type fold, IPR010473:Formin, GTPase-binding domain" CG43772 11-Aug-17 DroID_v2017_08 "Drer\fmnl2a, Drer\fmnl3, Drer\grid2ipa, Drer\fmnl1a, Drer\grid2ipb, Drer\diaph3, Drer\fmnl2b" "Scer\BNR1, Scer\BNI1" "Cele\fozi-1, Cele\frl-1, Cele\cyk-1" "Xtro\fmnl1, Xtro\fmnl2" "Mmus\Fmnl3, Mmus\Diaph3, Mmus\Fmnl1, Mmus\Fmnl2, Mmus\Diaph1, Mmus\Diaph2, Mmus\Grid2ip" "Hsap\FMNL1, Hsap\DIAPH2, Hsap\FMNL3, Hsap\GRID2IP, Hsap\DIAPH3, Hsap\FMNL2, Hsap\DIAPH1" FBgn0005721 l(1)TK129 lethal (1) TK129 http://flybase.org/reports/FBgn0005721 - gene - - - "l129, l(1)TK129" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0065217 l(2)SH2244 lethal (2) SH2244 http://flybase.org/reports/FBgn0065217 gene - - - "l(2)SH2244, l(2)SH2 2244" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265002 CG44153 - http://flybase.org/reports/FBgn0265002 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR001879 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001879 cellular_component ; GO:0005575 | no biological data available "CG31714, CG44153, CG5833, CG13132, CG42843, CG13134, CG13136, BP1029, CG34048" "IPR000742:EGF-like domain, IPR000859:CUB domain, IPR013032:EGF-like, conserved site, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain, IPR001879:GPCR, family 2, extracellular hormone receptor domain, IPR003599:Immunoglobulin subtype" CG44153 11-Aug-17 DroID_v2017_08 - - - - - Hsap\ADGRB3 FBgn0085264 CG34235 - http://flybase.org/reports/FBgn0085264 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34235 - CG34235 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037389 CR10991 - http://flybase.org/reports/FBgn0037389 pseudogene_attribute - - - "CG10991, CR10991" - CR10991 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261529 ms(2)34Fe male sterile (2) 34Fe http://flybase.org/reports/FBgn0261529 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatid differentiation ; GO:0048515 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG15287, ms(2)34Fe, BG:DS01068.1, ms(2)34Fh, ms(2)br40, l(2)34Fe, ms34Fe, br40" - CG15287 11-Aug-17 DroID_v2017_08 - - - - - - DRSC01905 K 0.03534417 0.087027854 0.716297159 -0.202715223 -0.800176198 1.667397239 FBgn0001649 l(1)ds1 lethal (1) discs small 1 http://flybase.org/reports/FBgn0001649 - gene - - - "l(1)d.sml.-1, l(1)ds1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030511 CG11158 - http://flybase.org/reports/FBgn0030511 protein_coding_gene purine nucleosidase activity ; GO:0008477 | inferred from biological aspect of ancestor with PANTHER:PTN000266727 purine nucleoside catabolic process ; GO:0006152 | inferred from biological aspect of ancestor with PANTHER:PTN000266727 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000266727 CG11158 "IPR001910:Inosine/uridine-preferring nucleoside hydrolase domain, IPR023186:Inosine/uridine-preferring nucleoside hydrolase" CG11158 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-4e7.3, Drer\si:ch211-201h21.5" Scer\URH1 "Cele\F13H8.3, Cele\Y43F8C.13" "Xtro\LOC100145000, Xtro\LOC548390, Xtro\LOC734042" - - "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0019881 anon-69Ab anon-69Ab http://flybase.org/reports/FBgn0019881 - gene - - - anon-69Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage&& adult stage , embryonic stage && larval stage && adult stage " FBgn0016952 tilI touch insensitive larva I http://flybase.org/reports/FBgn0016952 - gene - - - "line 411, tilI" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0085775 CR40847 - http://flybase.org/reports/FBgn0085775 non_protein_coding_gene - - - CR40847 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002483 l(3)SG42 lethal (3) SG42 http://flybase.org/reports/FBgn0002483 FBgn0004724 gene - - - "l(3)ds4, l(3)B4, l(3)SG42" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0267119 CR45559 - http://flybase.org/reports/FBgn0267119 non_protein_coding_gene - - - CR45559 - CR45559 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001855 l(1)tsUC34 lethal (1) tsUC34 http://flybase.org/reports/FBgn0001855 - gene - - - l(1)tsUC34 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0002497 l(3)SG58 lethal (3) SG58 http://flybase.org/reports/FBgn0002497 FBgn0004727 gene - - - "l(3)dsl-7, l(3)IIb1, l(3)dsl7, l(3)A7, SG58, l(3)SG58" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0039098 GILT3 Gamma-interferon-inducible lysosomal thiol reductase 3 http://flybase.org/reports/FBgn0039098 protein_coding_gene disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence model with Pfam:PF03227 oxidation-reduction process ; GO:0055114 | inferred from sequence model with Pfam:PF03227 cellular_component ; GO:0005575 | no biological data available "CG13822, GILT, GILT3" IPR004911:Gamma interferon inducible lysosomal thiol reductase GILT CG13822 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-197i20.6, Drer\ifi30" - "Cele\C02D5.2, Cele\Y18D10A.2, Cele\ZK669.2, Cele\F37H8.5, Cele\W04A4.3, Cele\R07E5.4, Cele\pqn-48, Cele\ZK669.3" Xtro\ifi30 Mmus\Ifi30 Hsap\IFI30 "viable,body color defective" mesothoracic tergum DRSC14672 I 2.339614071 0.20070092 0.752826588 -0.440910585 0.384792701 -0.216951976 FBgn0267273 CR45709 - http://flybase.org/reports/FBgn0267273 non_protein_coding_gene - - - CR45709 - CR45709 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036476 sstn stepping stone http://flybase.org/reports/FBgn0036476 protein_coding_gene - regulation of plasma membrane organization ; GO:1903729 | inferred from mutant phenotype regulation of cytoskeleton organization ; GO:0051493 | inferred from genetic interaction with Rho1 centrosome ; GO:0005813 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay "sstn, CG6945" - CG6945 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266276 CR44961 - http://flybase.org/reports/FBgn0266276 non_protein_coding_gene - - - CR44961 - CR44961 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267307 CR45743 - http://flybase.org/reports/FBgn0267307 non_protein_coding_gene - - - CR45743 - CR45743 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052765 CR33069 - http://flybase.org/reports/FBgn0052765 non_protein_coding_gene - - - "CG32765, CR33069" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030721 CG12698 - http://flybase.org/reports/FBgn0030721 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12698 "IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR014710:RmlC-like jelly roll fold" CG12698 11-Aug-17 DroID_v2017_08 "Drer\prkar1aa, Drer\prkar1b, Drer\prkar2b, Drer\prkar1ab, Drer\prkar2aa, Drer\prkar2ab" Scer\BCY1 Cele\B0336.12 "Xtro\prkar1a, Xtro\prkar2a, Xtro\prkar2b" "Mmus\Prkar1b, Mmus\Prkar2a, Mmus\Cnbd2, Mmus\Prkar1a, Mmus\Prkar2b" "Hsap\PRKAR2B, Hsap\CNBD2, Hsap\PRKAR2A, Hsap\PRKAR1B, Hsap\PRKAR1A" "viable,fertile" FBgn0259210 prom prominin http://flybase.org/reports/FBgn0259210 protein_coding_gene molecular_function ; GO:0003674 | no biological data available rhabdomere development ; GO:0042052 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008795 rhabdomere microvillus ; GO:0035996 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG42310, prom, CG30164, CG4556, CG30165, CG30166, eyc, Prom" IPR008795:Prominin CG42310 11-Aug-17 DroID_v2017_08 "Drer\prom1b, Drer\prom1a, Drer\ubxn11, Drer\nsfl1c, Drer\prom2, Drer\ubxn2a" Scer\SHP1 "Cele\M28.9, Cele\prmn-1, Cele\M28.8, Cele\M28.4, Cele\M28.2" "Xtro\ubxn11, Xtro\prom1, Xtro\prom2, Xtro\ubxn2a" "Mmus\Nsfl1c, Mmus\Prom2, Mmus\Ubxn2b, Mmus\Ubxn11, Mmus\Ubxn2a, Mmus\Prom1" "Hsap\UBXN11, Hsap\UBXN2A, Hsap\PROM2, Hsap\PROM1, Hsap\UBXN2B, Hsap\NSFL1C" FBgn0024948 N::sev N::sev http://flybase.org/reports/FBgn0024948 FBgn0024966 engineered_fusion_gene - - - N::sev - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040193 l(1)G0184 lethal (1) G0184 http://flybase.org/reports/FBgn0040193 gene - - - l(1)G0184 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "larva,pupa" FBgn0005345 Salmon Salmon http://flybase.org/reports/FBgn0005345 - gene - - - "Sa, Salmon" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,dominant,visible,lethal,recessive" pigment cell FBgn0011258 ms(3)73D male sterile (3) 73D http://flybase.org/reports/FBgn0011258 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - ms(3)73D - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0019671 mor(1)8 mortality gene (1)8 http://flybase.org/reports/FBgn0019671 - gene - - - mor(1)8 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0262583 CG43123 - http://flybase.org/reports/FBgn0262583 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43123, chr2R_3290447_3291368.0" - CG43123 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041100 park parkin http://flybase.org/reports/FBgn0041100 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from direct assay ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with HGNC:12490 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype positive regulation of compound eye pigmentation ; GO:0048078 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from direct assay mitophagy ; GO:0000422 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype zinc ion homeostasis ; GO:0055069 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay regulation of mitochondrion organization ; GO:0010821 | inferred from mutant phenotype negative regulation of mitochondrial fusion ; GO:0010637 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype positive regulation of mitochondrial fission ; GO:0090141 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from direct assay positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with bsk inferred from genetic interaction with hep mitochondrial fission ; GO:0000266 | inferred from genetic interaction with Drp1 inferred from genetic interaction with Marf inferred from genetic interaction with Opa1 protein autoubiquitination ; GO:0051865 | inferred from direct assay regulation of cellular response to oxidative stress ; GO:1900407 | inferred from direct assay sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from electronic annotation with InterPro:IPR003977 cytoplasm ; GO:0005737 | inferred from direct assay ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CG10523, dpk, SD01679, park, AAN12155.1, parkin, Park, Dpark, PK, pk, dParkin, Parkin, PARKIN" "IPR000626:Ubiquitin domain, IPR002867:IBR domain, IPR003977:E3 ubiquitin-protein ligase parkin, IPR029071:Ubiquitin-related domain, IPR019956:Ubiquitin, IPR031127:E3 ubiquitin ligase RBR family" CG10523 11-Aug-17 DroID_v2017_08 Drer\park2 - Cele\pdr-1 - Mmus\Park2 Hsap\PARK2 adult stage head

"visible,locomotor behavior defective,short lived,body size defective,female sterile,partially lethal - majority die,some die during pupal stage,viable,fertile,gravitaxis defective,neuroanatomy defective,progressive,chemical sensitive,locomotor rhythm defective,decreased cell death,male sterile,flightless,recessive,flight defective,cold sensitive,small body,decreased cell size,decreased cell number,hypoactive,jumping defective,sterile,developmental rate defective,increased cell death,drug conditional,smell perception defective,long lived,nutrition conditional,chemical conditional,oxidative stress response defective,courtship behavior defective,male,female fertile" "nurse cell,oocyte,egg,wing,mitochondrion,egg chamber,ovary,adult heart,cardial cell,mitochondriontin.C‘î4,dopaminergic PPL1 neuron,progressive,dopaminergic PAM neuron,dorsomedial neurosecretory cell,adult somatic muscle,indirect flight muscle,adult thorax,Nebenkern,myofibril & skeletal muscle of thorax,mitochondrion & skeletal muscle of thorax,Nebenkern derivative,follicle cell,dopaminergic neuron,indirect flight muscle & mitochondrion,indirect flight muscle & nuclear membrane,mitochondrionPc-MK),myofibrilPc-MK),neuron,flight muscle,spermatid,spermatid axoneme,elongation stage spermatid,individualization stage spermatid,mitochondrial crista,adult heart chamber,mesothoracic cleft,ectopic,mitochondrion & dorso-lateral dopaminergic neuronple.PF,eye" FBgn0035904 GstO3 Glutathione S transferase O3 http://flybase.org/reports/FBgn0035904 protein_coding_gene "glutathione dehydrogenase (ascorbate) activity ; GO:0045174 | inferred from direct assay glutathione transferase activity ; GO:0004364 | inferred from direct assay transferase activity, transferring sulfur-containing groups ; GO:0016782 | inferred from direct assay pyrimidodiazepine synthase activity ; GO:0004734 | inferred from direct assay NOT" glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "T14, CG6776, GstO3, GSTO3, DmGSTO3" "IPR004045:Glutathione S-transferase, N-terminal, IPR005442:Glutathione S-transferase, omega-class, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG6776 11-Aug-17 DroID_v2017_08 "Drer\gsto2, Drer\gsto1, Drer\gstr" Scer\GTT2 "Cele\gsto-1, Cele\gsto-3, Cele\gst-44, Cele\gsto-2, Cele\C02D5.4" "Xtro\LOC100498493, Xtro\gsto1, Xtro\gsto2" "Mmus\Gsto1, Mmus\Gsto2" "Hsap\GSTO1, Hsap\GSTO2" "viable,fertile" FBgn0027784 Prp18 Prp18 http://flybase.org/reports/FBgn0027784 - protein_coding_gene second spliceosomal transesterification activity ; GO:0000386 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000313715 "generation of catalytic spliceosome for second transesterification step ; GO:0000350 | inferred from biological aspect of ancestor with PANTHER:PTN000313715 nuclear retention of unspliced pre-mRNA at the site of transcription ; GO:0071048 | inferred from biological aspect of ancestor with PANTHER:PTN000313715 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000003238" U2-type post-spliceosomal complex ; GO:0071021 | inferred from biological aspect of ancestor with PANTHER:PTN000313715 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000003238 U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000313715 U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000313715 "CG6011, Prp18, prp18" "IPR004098:Prp18, IPR014906:Pre-mRNA processing factor 4 (PRP4)-like" CG6011 11-Aug-17 DroID_v2017_08 Drer\prpf18 Scer\PRP18 Cele\F32B6.3 Xtro\prpf18 Mmus\Prpf18 Hsap\PRPF18 "viable,fertile" DRSC16802 I 1.110299876 1.85196 0.525874934 0.831491582 -0.559329725 0.124875137 FBgn0000330 cm carmine http://flybase.org/reports/FBgn0000330 "FBgn0020512, FBgn0024949" protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with AP-1μ inferred from sequence or structural similarity with AP-2μ "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001392, InterPro:IPR018240 synaptic vesicle coating ; GO:0016183 | traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement exocytosis ; GO:0006887 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype intracellular transport ; GO:0046907 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype lysosome organization ; GO:0007040 | inferred from sequence or structural similarity determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype vesicle coating ; GO:0006901 | traceable author statement" "clathrin adaptor complex ; GO:0030131 | inferred from electronic annotation with InterPro:IPR001392, InterPro:IPR018240 coated vesicle ; GO:0030135 | traceable author statement synaptic vesicle ; GO:0008021 | traceable author statement AP-3 adaptor complex ; GO:0030123 | inferred from sequence or structural similarity with HGNC:569" "cm, cg3035, CG3035, mu3, Dmu3, AP-3, l(1)VEM119, Mu3, CG32731, ap-3, AP3mu3, apm3, AP-3mu" "IPR018240:Clathrin adaptor, mu subunit, conserved site, IPR001392:Clathrin adaptor, mu subunit, IPR011012:Longin-like domain, IPR028565:Mu homology domain" CG3035 11-Aug-17 DroID_v2017_08 "Drer\ap3m1, Drer\ap3m2" "Scer\APM1, Scer\APM3" "Cele\apm-3, Cele\R11G1.1, Cele\rme-2" Xtro\ap3m2 "Mmus\Ap3m2, Mmus\Ap3m1" "Hsap\AP3M1, Hsap\AP3M2" embryonic stage -- adult stage "viable,fertile,visible,recessive,eye color defective,short lived,male,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective" "pigment cell,secondary pigment cell pigment granule,tertiary pigment cell pigment granule,rhabdomere,Malpighian tubule,ommatidium,photoreceptor cell,wing,eye,ganglion mother cell,mesothoracic tergum" FBgn0053278 CG33278 - http://flybase.org/reports/FBgn0053278 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18656, cg18656, CG33278" - CG33278 11-Aug-17 DroID_v2017_08 "Drer\wu:fq32h04, Drer\hnrnpc, Drer\zcrb1, Drer\eif4ba, Drer\trnau1apa, Drer\ncoa5, Drer\dazl, Drer\hnrnpaba, Drer\srsf10a, Drer\eif4h, Drer\hnrnpabb, Drer\zgc:55733, Drer\hnrnpa1b, Drer\cirbpa, Drer\raly, Drer\rbm34, Drer\trnau1apb, Drer\hnrnpd, Drer\hnrnpa3" "Scer\MUD1, Scer\NGR1, Scer\NAB6, Scer\NOP12, Scer\CWC2, Scer\NOP6, Scer\NAM8, Scer\MRN1" - "Xtro\hnrnpa3, Xtro\cirbp, Xtro\hnrnpab, Xtro\rbm34, Xtro\dazl, Xtro\eif4h, Xtro\hnrnpa2b1, Xtro\trnau1ap, Xtro\eif4b, Xtro\hnrnpd, Xtro\hnrnpa1, Xtro\hnrnpdl, Xtro\raly, Xtro\hnrnpc, Xtro\ralyl" "Mmus\Hnrnpab, Mmus\Srsf10, Mmus\Tra2b, Mmus\Dazl, Mmus\Rbm34, Mmus\Slirp, Mmus\Boll, Mmus\Hnrnpa2b1, Mmus\Srsf12, Mmus\Hnrnpc, Mmus\Rbm31y, Mmus\Zcrb1, Mmus\Hnrnpd, Mmus\Eif4b, Mmus\Gm21379, Mmus\Cirbp, Mmus\Eif4h, Mmus\Hnrnpa1, Mmus\Hnrnpa3, Mmus\Trnau1ap, Mmus\Raly" "Hsap\EIF4H, Hsap\DAZ3, Hsap\TRNAU1AP, Hsap\HNRNPA1L2, Hsap\RBM34, Hsap\HNRNPD, Hsap\HNRNPA1, Hsap\SLIRP, Hsap\DAZ1, Hsap\HNRNPA2B1, Hsap\RALYL, Hsap\CIRBP, Hsap\HNRNPCL1, Hsap\HNRNPAB, Hsap\RALY, Hsap\BOLL, Hsap\DAZL, Hsap\DAZ2, Hsap\EIF4B, Hsap\DAZ4, Hsap\SRSF10, Hsap\HNRNPC, Hsap\HNRNPA3, Hsap\RBM3" viable DRSC10336 K 0.163230259 0.058415107 -0.430984239 0.122365481 1.454229252 1.699505021 FBgn0065377 l(2)SH1673 lethal (2) SH1673 http://flybase.org/reports/FBgn0065377 gene - - - "l(2)SH1673, l(2)SH2 1673" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011872 tRNA:Gly-GCC-1-13 transfer RNA:Glycine-GCC 1-13 http://flybase.org/reports/FBgn0011872 "FBgn0003783, FBgn0050210, FBgn0060228" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "CR30210, AE002575.trna3-GlyGCC, tRNA:G:GCC:AE002575-a, tRNA:gly3:57BCb, tRNA[Gly-GCC], chr2R.trna47-GlyGCC, tRNA-Gly-GCC-1-13, tRNA:Gly-GCC-1-13, tRNA:G3:57BCb, GGC" - CR30210 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015411 l(1)14ABb lethal (1) 14ABb http://flybase.org/reports/FBgn0015411 - gene - - - l(1)14ABb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026667 l(1)G0132 lethal (1) G0132 http://flybase.org/reports/FBgn0026667 - gene - - - l(1)G0132 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0027268 l(1)G0212 lethal (1) G0212 http://flybase.org/reports/FBgn0027268 - gene - - - l(1)G0212 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0020246 tss toothless http://flybase.org/reports/FBgn0020246 - gene - - - tss - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040651 CG15458 - http://flybase.org/reports/FBgn0040651 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial proton-transporting ATP synthase complex ; GO:0005753 | inferred from biological aspect of ancestor with PANTHER:PTN002145699 CG15458 - CG15458 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-80c12.10 - - - Mmus\Usmg5 Hsap\USMG5 viable FBgn0036083 Ir67b Ionotropic receptor 67b http://flybase.org/reports/FBgn0036083 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir67b, DmelIR67b, CG12303, IR67b" - CG12303 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035793 CG7546 - http://flybase.org/reports/FBgn0035793 protein_coding_gene polyubiquitin binding ; GO:0031593 | inferred from sequence or structural similarity with MGI:MGI:1919439 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with MGI:MGI:1919439 cytosol ; GO:0005829 | inferred from sequence or structural similarity with MGI:MGI:1919439 "clone 2.45, anon-EST:Liang-2.45, CG7546" "IPR000626:Ubiquitin domain, IPR019954:Ubiquitin conserved site, IPR029071:Ubiquitin-related domain, IPR021925:Protein of unknown function DUF3538" CG7546 11-Aug-17 DroID_v2017_08 "Drer\bag6, Drer\bag6l" - Cele\ZK688.5 Xtro\bag6 Mmus\Bag6 Hsap\BAG6 "viable,fertile,visible,body color defective" mesothoracic tergum FBgn0028041 l(3)S099013 lethal (3) S099013 http://flybase.org/reports/FBgn0028041 gene - - - "1002/02, 0990/13, l(3)S099013" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001443 l(1)7Ce lethal (1) 7Ce http://flybase.org/reports/FBgn0001443 - gene - - - l(1)7Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0019955 Nrt::Tmar\AChE Nrt::Tmar\AChE http://flybase.org/reports/FBgn0019955 - engineered_fusion_gene - - - Nrt::Tmar\AChE - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022091 l(2)k07308 lethal (2) k07308 http://flybase.org/reports/FBgn0022091 - gene - - - l(2)k07308 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259484 smo::Mmmm\EB2 - http://flybase.org/reports/FBgn0259484 engineered_fusion_gene - - - "smo::Mmmm\EB2, EB2-SMO" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042127 CG18789 - http://flybase.org/reports/FBgn0042127 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 - - CG18789 "IPR000571:Zinc finger, CCCH-type" CG18789 11-Aug-17 DroID_v2017_08 Drer\nupl2 - - Xtro\nupl2 Mmus\Nupl2 Hsap\NUPL2 FBgn0262828 CR43199 - http://flybase.org/reports/FBgn0262828 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43199, noncoding_22394, CR43199" - CR43199 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028361 l(1)G0140 lethal (1) G0140 http://flybase.org/reports/FBgn0028361 gene - - - l(1)G0140 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0044514 l(2)Mai179 lethal (2) Mai179 http://flybase.org/reports/FBgn0044514 gene - - - "l(2)Mai179, Mai179" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265338 CR44292 - http://flybase.org/reports/FBgn0265338 non_protein_coding_gene - - - CR44292 - CR44292 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065112 p45 p45 http://flybase.org/reports/FBgn0065112 gene - - - p45 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052520 tRNA:Tyr-GTA-1-1 transfer RNA:Tyrosine-GTA 1-1 http://flybase.org/reports/FBgn0052520 tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "AE002620.trna1-TyrGTA, tRNA[Tyr][[1gamma]], tRNA:tyr1:19F, tRNA:Y1:19F, tRNA:Y:GTA:AE002620-a, CR32520, chrX.trna18-TyrGTA, tRNA-Tyr-GTA-1-1, tRNA:Tyr-GTA-1-1, tRNA:CR32520, UAC" - CR32520 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002757 mit(1)7 mitotic 7 http://flybase.org/reports/FBgn0002757 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0024938 Ruf Ruf http://flybase.org/reports/FBgn0024938 - gene - - - Ruf - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "eye,wing,wing vein" FBgn0265482 BG01907 - http://flybase.org/reports/FBgn0265482 gene - - - BG01907 - - 11-Aug-17 DroID_v2017_08 - - - - - - sleep defective FBgn0037570 CG11693 - http://flybase.org/reports/FBgn0037570 protein_coding_gene molecular_function ; GO:0003674 | no biological data available developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 cellular_component ; GO:0005575 | no biological data available CG11693 IPR007999:Protein of unknown function DUF745 CG11693 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266269 Hto-WP(2)NAW - http://flybase.org/reports/FBgn0266269 gene - - - Hto-WP(2)NAW - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing hair,wing" FBgn0015519 nAChRalpha3 nicotinic Acetylcholine Receptor alpha3 http://flybase.org/reports/FBgn0015519 - protein_coding_gene acetylcholine receptor activity ; GO:0015464 | contributes_to inferred from direct assay acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity acetylcholine-gated cation channel activity ; GO:0022848 | contributes_to inferred from direct assay cation transport ; GO:0006812 | inferred from direct assay postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity acetylcholine-gated channel complex ; GO:0005892 | inferred from direct assay "nAChR, Dalpha3, nAcRe, nAcRalpha-7E, nACRalpha-7E, Da3, D[a3], CG2302, Acr7E, alpha3, lincRNA.965, nAChRalpha3, Dalpha3 nAChR, nicra3" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG2302 11-Aug-17 DroID_v2017_08 "Drer\chrnb1l, Drer\chrnb3b, Drer\htr3a, Drer\LOC798522, Drer\chrna5, Drer\chrna1, Drer\chrna6, Drer\chrnd, Drer\chrna4b, Drer\si:ch73-380n15.2, Drer\chrng, Drer\si:ch211-39a7.1, Drer\chrnb1, Drer\si:ch211-256e16.4, Drer\chrnb2b, Drer\chrnb3a, Drer\chrnb2l, Drer\chrna10a, Drer\chrne, Drer\htr3b, Drer\chrna3, Drer\LOC101882451, Drer\chrnb4, Drer\chrna2b, Drer\chrnb2a, Drer\chrna9, Drer\chrna2a" - "Cele\unc-38, Cele\acr-11, Cele\acr-2, Cele\acr-16, Cele\acr-21, Cele\acr-14, Cele\unc-63, Cele\acr-15, Cele\acr-10, Cele\acr-12, Cele\acr-7, Cele\acr-8, Cele\acr-25, Cele\eat-2, Cele\acr-9, Cele\lev-8, Cele\lgc-4, Cele\lev-1, Cele\acr-3, Cele\acr-19, Cele\acr-6" "Xtro\chrna5, Xtro\chrna6, Xtro\chrng, Xtro\chrna2, Xtro\chrna7, Xtro\chrna9, Xtro\chrnb3, Xtro\chrnb2, Xtro\chrne, Xtro\chrna1, Xtro\chrnd, Xtro\chrna1.2" "Mmus\Chrna5, Mmus\Chrna10, Mmus\Chrna9, Mmus\Chrng, Mmus\Htr3a, Mmus\Chrna7, Mmus\Chrnd, Mmus\Chrna6, Mmus\Chrne, Mmus\Chrna1, Mmus\Chrna3, Mmus\Chrnb2, Mmus\Chrnb1, Mmus\Chrnb3, Mmus\Htr3b, Mmus\Chrna2, Mmus\Chrnb4, Mmus\Chrna4" "Hsap\CHRNA7, Hsap\CHRNB3, Hsap\CHRNA5, Hsap\CHRNA6, Hsap\CHRNG, Hsap\CHRFAM7A, Hsap\HTR3B, Hsap\CHRNA3, Hsap\CHRNA9, Hsap\CHRNA2, Hsap\CHRNA1, Hsap\CHRND, Hsap\HTR3D, Hsap\HTR3E, Hsap\CHRNB2, Hsap\CHRNB1, Hsap\HTR3C, Hsap\CHRNE, Hsap\CHRNA4, Hsap\CHRNB4, Hsap\CHRNA10, Hsap\HTR3A" viable FBgn0002658 mat(2)cell-G maternal effect cellularisation defect G http://flybase.org/reports/FBgn0002658 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "cell-QE1, QE1, mat(2)cellQE1, mat(2)cell-G" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0005706 l(1)TK109 lethal (1) TK109 http://flybase.org/reports/FBgn0005706 - gene - - - "l109, l(1)TK109" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" eye FBgn0027503 CG11970 - http://flybase.org/reports/FBgn0027503 - protein_coding_gene - - Ino80 complex ; GO:0031011 | inferred from electronic annotation with InterPro:IPR024867 "BcDNA:LD23876, CG11970" "IPR025220:NFRKB winged helix-like domain, IPR024867:Nuclear factor related to kappa-B-binding protein" CG11970 11-Aug-17 DroID_v2017_08 Drer\nfrkb - - Xtro\nfrkb Mmus\Nfrkb Hsap\NFRKB FBgn0030716 CG9170 - http://flybase.org/reports/FBgn0030716 protein_coding_gene - - - "anon-WO0140519.214, CG9170" IPR001202:WW domain CG9170 11-Aug-17 DroID_v2017_08 - - - - Mmus\Cep164 Hsap\CEP164 viable FBgn0013717 not non-stop http://flybase.org/reports/FBgn0013717 "FBgn0010766, FBgn0011415, FBgn0063787" protein_coding_gene "thiol-dependent ubiquitinyl hydrolase activity ; GO:0036459 | inferred from electronic annotation with InterPro:IPR001394, InterPro:IPR018200 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001607 protein binding ; GO:0005515 | inferred from physical interaction with Sgf11 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence model" "histone deubiquitination ; GO:0016578 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype axon target recognition ; GO:0007412 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from genetic interaction with Prosβ6 protein deubiquitination ; GO:0016579 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype histone deubiquitination ; GO:0016578 | inferred from direct assay" DUBm complex ; GO:0071819 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "i155, CG4166, l(3)02069, l(3)j9A6, anon-WO0257455.9, not, NOT, Nonstop, nonstop, UBP8, USP22, Upb8, Not, Q9VVR1" "IPR018200:Ubiquitin specific protease, conserved site, IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR001607:Zinc finger, UBP-type, IPR028889:Ubiquitin specific protease domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4166 11-Aug-17 DroID_v2017_08 "Drer\usp22, Drer\usp2a, Drer\usp4, Drer\usp49, Drer\usp8, Drer\usp44, Drer\usp30, Drer\usp3, Drer\usp32, Drer\usp11" "Scer\UBP5, Scer\UBP1, Scer\DOA4, Scer\UBP8, Scer\UBP12" "Cele\usp-33, Cele\usp-50, Cele\usp-3, Cele\H34C03.2, Cele\F07A11.4, Cele\cyk-3" "Xtro\usp22, Xtro\usp49, Xtro\usp30, Xtro\usp3, Xtro\usp44, Xtro\usp15" "Mmus\Usp51, Mmus\Usp27x, Mmus\Usp2, Mmus\Usp32, Mmus\Usp15, Mmus\Usp4, Mmus\Usp49, Mmus\Usp22, Mmus\Usp3, Mmus\Usp30, Mmus\Usp44, Mmus\Usp8, Mmus\Usp11" "Hsap\USP3, Hsap\USP32, Hsap\USP49, Hsap\USP30, Hsap\USP51, Hsap\USP44, Hsap\USP27X, Hsap\USP2, Hsap\USP4, Hsap\USP11, Hsap\USP8, Hsap\USP22" "suppressor of variegation,neuroanatomy defective,somatic clone,lethal,recessive,enhancer of variegation,dominant,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,lethal - all die before end of prepupal stage,partially,some die during prepupal stage,planar polarity defective,visible,heat sensitive" "photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina anlage,precursor,larval inner optic anlage,larval outer optic anlage,axon & photoreceptor cell R2,axon & photoreceptor cell R3,axon & photoreceptor cell R4,axon & photoreceptor cell R5,photoreceptor cell & axon,lamina,lamina plexus,medulla,marginal glial cell,epithelial glial cell,medulla neuropil glial cell,photoreceptor cell & axonW4),ommatidium,somatic clone,eye photoreceptor cell,wing hair,wing,wing margin bristle,scutellar bristle,supernumerary" FBgn0010245 Mst77F-PsiY3 Mst77F pseudogene on Y 3 http://flybase.org/reports/FBgn0010245 - pseudogene_attribute - - - "18c, Mst77F-PsiY3, Mst77-Psi3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004214 l(3)84Fb lethal (3) 84Fb http://flybase.org/reports/FBgn0004214 - gene - - - l(3)84Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260237 CG42511 - http://flybase.org/reports/FBgn0260237 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN002006313 cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:28093 receptor localization to non-motile cilium ; GO:0097500 | inferred from biological aspect of ancestor with PANTHER:PTN002006313 BBSome ; GO:0034464 | inferred from biological aspect of ancestor with PANTHER:PTN002006313 BBSome ; GO:0034464 | inferred from sequence or structural similarity with HGNC:28093 "CG42511, BBIP1" IPR028233:Cilia BBSome complex subunit 10 CG42511 11-Aug-17 DroID_v2017_08 Drer\bbip1 - "Cele\dct-14, Cele\K07C11.10" - Mmus\Bbip1 Hsap\BBIP1 FBgn0015491 l(3)65ACa lethal (3) 65ACa http://flybase.org/reports/FBgn0015491 - gene - - - "I, l(3)65ACa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031367 c-cup calcutta cup http://flybase.org/reports/FBgn0031367 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000031653 - membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 "CG15623, c-cup" IPR001199:Cytochrome b5-like heme/steroid binding domain CG15623 11-Aug-17 DroID_v2017_08 "Drer\pgrmc2, Drer\pgrmc1, Drer\nenf" Scer\DAP1 Cele\vem-1 "Xtro\pgrmc2, Xtro\nenf, Xtro\pgrmc1" "Mmus\Nenf, Mmus\Pgrmc1, Mmus\Pgrmc2" "Hsap\PGRMC2, Hsap\PGRMC1, Hsap\NENF" viable FBgn0029603 CG14053 - http://flybase.org/reports/FBgn0029603 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT10359, CG14053" - CG14053 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061076 l(3)S015102b lethal (3) S015102b http://flybase.org/reports/FBgn0061076 gene - - - "0151/02, l(3)S015102b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060949 l(3)S037703 lethal (3) S037703 http://flybase.org/reports/FBgn0060949 gene - - - "0377/03, l(3)S037703" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264638 creeper creeper http://flybase.org/reports/FBgn0264638 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - creeper - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0016823 l(1)MZ10 lethal (1) MZ10 http://flybase.org/reports/FBgn0016823 - gene - - - "l(1)MZ10, M10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037405 CG1077 - http://flybase.org/reports/FBgn0037405 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern chorion ; GO:0042600 | inferred by curator from GO:0007304 "CG1077, anon-f" IPR002350:Kazal domain CG1077 11-Aug-17 DroID_v2017_08 - - Cele\F29G6.1 - "Mmus\Spink12, Mmus\Spink5, Mmus\Spink6" "Hsap\SPINK6, Hsap\SPINK5" "viable,fertile" FBgn0086361 alph alphabet http://flybase.org/reports/FBgn0086361 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from electronic annotation with InterPro:IPR015655 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR012911 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR012911 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement phosphatase activity ; GO:0016791 | inferred from direct assay "protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR015655 regulation of p38MAPK cascade ; GO:1900744 | inferred from genetic interaction with lic response to UV-C ; GO:0010225 | inferred from mutant phenotype negative regulation of stress-activated protein kinase signaling cascade ; GO:0070303 | inferred from mutant phenotype inferred from genetic interaction with Rac1 protein dephosphorylation ; GO:0006470 | non-traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of stress-activated MAPK cascade ; GO:0032873 | inferred from genetic interaction with hep inferred from genetic interaction with slpr inferred from genetic interaction with lic negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype response to paraquat ; GO:1901562 | inferred from mutant phenotype negative regulation of MAP kinase activity ; GO:0043407 | inferred from mutant phenotype positive regulation of R7 cell differentiation ; GO:0045678 | inferred from mutant phenotype inferred from genetic interaction with aop inferred from genetic interaction with RasGAP1 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from genetic interaction with slpr imaginal disc fusion, thorax closure ; GO:0046529 | inferred from genetic interaction with slpr dephosphorylation ; GO:0016311 | inferred from direct assay negative regulation of ERK1 and ERK2 cascade ; GO:0070373 | inferred from genetic interaction with Ras85D response to oxidative stress ; GO:0006979 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype inferred from genetic interaction with hep compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available "SK3-1, alph, CG1906, pp2c99B, PP2Cb" "IPR015655:Protein phosphatase 2C family, IPR012911:Protein serine/threonine phosphatase 2C, C-terminal, IPR001932:PPM-type phosphatase domain, IPR000222:PPM-type phosphatase, divalent cation binding" CG1906 11-Aug-17 DroID_v2017_08 "Drer\ppm1ba, Drer\ppm1f, Drer\ppm1nb, Drer\ppm1aa, Drer\ppm1ab, Drer\ppm1bb, Drer\ppm1na, Drer\ppm1g" "Scer\PTC3, Scer\PTC2, Scer\PTC1" "Cele\F42G9.1, Cele\ppm-2, Cele\ppm-1, Cele\fem-2" "Xtro\ppm1a, Xtro\ppm1b" "Mmus\Ppm1n, Mmus\Ppm1f, Mmus\Ppm1e, Mmus\Ppm1b, Mmus\Ppm1g, Mmus\Ppm1a" "Hsap\PPM1N, Hsap\PPM1G, Hsap\PPM1F, Hsap\PPM1A, Hsap\PPM1E, Hsap\PPM1B" DRSC15398 K 0.797108569 0.918843224 1.337706125 0.732744976 0.303647055 1.518854699 FBgn0040929 CG12659 - http://flybase.org/reports/FBgn0040929 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR029525 chromatin remodeling ; GO:0006338 | inferred from biological aspect of ancestor with PANTHER:PTN001260679" Ino80 complex ; GO:0031011 | inferred from electronic annotation with InterPro:IPR029525 CG12659 "IPR013272:Vps72/YL1, C-terminal, IPR029525:INO80 complex, subunit Ies6" CG12659 11-Aug-17 DroID_v2017_08 Drer\ino80c Scer\IES6 "Cele\F55G11.2, Cele\C49G7.7, Cele\F55G11.6" - Mmus\Ino80c Hsap\INO80C "viable,fertile" FBgn0261929 5-HT2B 5-hydroxytryptamine (serotonin) receptor 2B http://flybase.org/reports/FBgn0261929 protein_coding_gene G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity with HGNC:5294 serotonin receptor signaling pathway ; GO:0007210 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with HGNC:5294 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:5294" "CG42796, CG8007, anon-WO0170980.95, anon-WO0170980.94, CG7994, anon-WO0170980.98, anon-WO0170980.97, 5-HT2B, d5-HT2B, 5-HT[[2B]], 5HT1b" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG42796 11-Aug-17 DroID_v2017_08 "Drer\hrh3, Drer\LOC100331077, Drer\htr2cl2, Drer\hrh4, Drer\LOC101886918, Drer\htr2b" - "Cele\dop-5, Cele\ser-1" - "Mmus\Hrh3, Mmus\Hrh4, Mmus\Htr2c, Mmus\Htr2a, Mmus\Htr2b" "Hsap\HTR2C, Hsap\HTR2A, Hsap\HRH4, Hsap\HTR2B, Hsap\HRH3" FBgn0043558 Su(ro[DOM])1993 Su(ro[DOM])1993 http://flybase.org/reports/FBgn0043558 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])1993 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,visible" "eye,wing" FBgn0259735 CG42389 - http://flybase.org/reports/FBgn0259735 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available plasma membrane ; GO:0005886 | inferred from direct assay "CG42389, CG13260, CG4668, CT15049, CT15043, clone 1.16, anon-EST:Liang-1.16, CG13261, CG31738" "IPR003961:Fibronectin type III, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013783:Immunoglobulin-like fold" CG42389 11-Aug-17 DroID_v2017_08 "Drer\fndc3ba, Drer\fndc3bb" - "Cele\C53A5.13, Cele\let-805, Cele\C34F6.10" "Xtro\fndc3a, Xtro\fndc3b" "Mmus\Fndc3b, Mmus\Fnd3c2, Mmus\Fndc3c1, Mmus\Fndc3a" "Hsap\FNDC3A, Hsap\FNDC3B" FBgn0082831 pps protein partner of snf http://flybase.org/reports/FBgn0082831 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965, InterPro:IPR017890 hydrolase activity, acting on acid anhydrides ; GO:0016817 | inferred from electronic annotation with InterPro:IPR006576 protein binding ; GO:0005515 | inferred from physical interaction with snf" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR003618 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | colocalizes_with inferred from direct assay "spp, Spp, SPP, pps, CG6525, FBgn0082831" "IPR001965:Zinc finger, PHD-type, IPR003618:Transcription elongation factor S-II, central domain, IPR006576:BRK domain, IPR012921:Spen paralogue and orthologue SPOC, C-terminal, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6525 11-Aug-17 DroID_v2017_08 "Drer\dido1, Drer\phf20l1, Drer\kmt2d, Drer\kmt2e, Drer\ash1l, Drer\whsc1l1, Drer\setd1ba, Drer\whsc1, Drer\si:ch73-181d5.4, Drer\phf20b, Drer\phf3, Drer\nsd1b" "Scer\SET4, Scer\SET3, Scer\DST1, Scer\CTI6, Scer\BYE1, Scer\SET2, Scer\SET1" "Cele\set-26, Cele\set-12, Cele\met-1, Cele\mes-4, Cele\set-5, Cele\set-16, Cele\C16A11.4, Cele\set-9, Cele\lin-59" "Xtro\setd1b, Xtro\phf3" "Mmus\Nsd1, Mmus\Setd2, Mmus\Setd1a, Mmus\Dido1, Mmus\Kmt2e, Mmus\Kmt2d, Mmus\Whsc1, Mmus\Whsc1l1, Mmus\Phf3, Mmus\Setd1b, Mmus\Phf20l1, Mmus\Kmt2c, Mmus\Spocd1, Mmus\Setd5, Mmus\Ash1l" "Hsap\SETD1B, Hsap\KMT2D, Hsap\ASH1L, Hsap\SETD2, Hsap\PHF20, Hsap\PHF3, Hsap\PHF20L1, Hsap\SPOCD1, Hsap\WHSC1, Hsap\SETD1A, Hsap\KMT2E, Hsap\NSD1, Hsap\SETD5, Hsap\WHSC1L1, Hsap\KMT2C, Hsap\DIDO1" female sterile ovary DRSC16057 E 0.049398803 -0.169651704 0.886425959 -1.914224849 0.991188091 1.118335948 FBgn0053376 5SrRNA:CR33376 5SrRNA:CR33376 http://flybase.org/reports/FBgn0053376 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33376, 5SrRNA:CR33376" - CR33376 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030206 CG2889 - http://flybase.org/reports/FBgn0030206 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG2889 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG2889 11-Aug-17 DroID_v2017_08 "Drer\prdm5, Drer\zgc:153116" Scer\ZAP1 "Cele\zfp-2, Cele\Y48G8AL.10, Cele\spr-3" Xtro\prdm5 "Mmus\Zfp35, Mmus\Zfy1, Mmus\Zfp652, Mmus\Zfy2" "Hsap\ZNF197, Hsap\ZNF677, Hsap\PRDM5" "viable,fertile" FBgn0266506 s-349 - http://flybase.org/reports/FBgn0266506 gene - - - s-349 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010549 l(2)03659 lethal (2) 03659 http://flybase.org/reports/FBgn0010549 "FBgn0016971, FBgn0033406, FBgn0033407" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 multicellular organism development ; GO:0007275 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN002384094 "Dme_CG8799, CG8799, A, hspr, CG11803, l(2)03659" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8799 11-Aug-17 DroID_v2017_08 "Drer\abcc4, Drer\cftr, Drer\abcc10, Drer\abcc13, Drer\abcc3, Drer\abcc1, Drer\abcc12, Drer\abcc9, Drer\abcc5, Drer\LOC100329706, Drer\abcc6b.2, Drer\abcc8, Drer\abcc6a, Drer\abcc2" "Scer\YKR104W, Scer\VMR1, Scer\BPT1, Scer\NFT1, Scer\YCF1, Scer\YOR1, Scer\YBT1" "Cele\mrp-3, Cele\mrp-4, Cele\mrp-1, Cele\pgp-10, Cele\mrp-5, Cele\mrp-7, Cele\mrp-2, Cele\mrp-6, Cele\mrp-8" "Xtro\abcc6, Xtro\abcc3, Xtro\abcc4, Xtro\abcc10, Xtro\abcc1, Xtro\cftr" "Mmus\Abcc4, Mmus\Abcc9, Mmus\Abcc5, Mmus\Cftr, Mmus\Abcc10, Mmus\Abcc1, Mmus\Abcc12, Mmus\Abcc3, Mmus\Abcc6, Mmus\Abcc2, Mmus\Abcc8" "Hsap\CFTR, Hsap\ABCC11, Hsap\ABCC8, Hsap\ABCC1, Hsap\ABCC10, Hsap\ABCC9, Hsap\ABCC12, Hsap\ABCC2, Hsap\ABCC3, Hsap\ABCC5, Hsap\ABCC4, Hsap\ABCC6" "lethal,recessive,partially lethal - majority live,sterile,viable" "head bristle,macrochaeta & thorax03659EMS93),scutellar bristle,wing,macrochaeta & thorax03659EMS5)" FBgn0086683 Spf45 Spf45 http://flybase.org/reports/FBgn0086683 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467, InterPro:IPR000504 molecular_function ; GO:0003674 | no biological data available" "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 DNA repair ; GO:0006281 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with HGNC:10548 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from genetic interaction with Sxl" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG17540, RBM17, SPF45, spf-45, dSPF45, spf45, Spf45, dRBM17" "IPR000504:RNA recognition motif domain, IPR000467:G-patch domain, IPR016967:Splicing factor, SPF45, IPR034653:SPF45, RNA recognition motif, IPR003954:RNA recognition motif domain, eukaryote" CG17540 11-Aug-17 DroID_v2017_08 "Drer\rbm17, Drer\u2af2b" "Scer\GDS1, Scer\YHR140W, Scer\TCM62, Scer\GCR2, Scer\SEC72, Scer\SLA1, Scer\GDH2" "Cele\skpo-1, Cele\F09F3.5, Cele\F58B3.7" Xtro\rbm17 "Mmus\Rbm17, Mmus\Ptgs2" "Hsap\PTGS2, Hsap\SCN10A, Hsap\RBM17" "viable,visible,fertile,DNA repair defective,chemical sensitive" trichogen cell FBgn0000948 fs(2)A18 female sterile (2) A18 http://flybase.org/reports/FBgn0000948 - gene - - - fs(2)A18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "ovary,oocyte" FBgn0002886 mus112 mutagen-sensitive 112 http://flybase.org/reports/FBgn0002886 - gene - - - mus112 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0267565 CR45905 - http://flybase.org/reports/FBgn0267565 non_protein_coding_gene - - - CR45905 - CR45905 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029075 l(1)G0141 lethal (1) G0141 http://flybase.org/reports/FBgn0029075 gene - - - l(1)G0141 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male sterile,partially lethal - majority die,recessive" chaeta FBgn0263767 CR43684 - http://flybase.org/reports/FBgn0263767 non_protein_coding_gene - - - CR43684 - CR43684 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065439 l(2)SH1464 lethal (2) SH1464 http://flybase.org/reports/FBgn0065439 gene - - - "l(2)SH1464, l(2)SH2 1464" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060721 l(3)S068601b lethal (3) S068601b http://flybase.org/reports/FBgn0060721 gene - - - "0686/01, l(3)S068601b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0085250 CG34221 - http://flybase.org/reports/FBgn0085250 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34221 - CG34221 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033836 CG18278 - http://flybase.org/reports/FBgn0033836 protein_coding_gene N-acetylglucosamine-6-sulfatase activity ; GO:0008449 | inferred from electronic annotation with InterPro:IPR012251 glycosaminoglycan metabolic process ; GO:0030203 | inferred from electronic annotation with InterPro:IPR012251 - CG18278 "IPR000917:Sulfatase, N-terminal, IPR012251:N-acetylglucosamine-6-sulfatase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site" CG18278 11-Aug-17 DroID_v2017_08 "Drer\sulf1, Drer\sulf2a, Drer\arsk, Drer\sulf2b, Drer\gnsb, Drer\gnsa" - Cele\sul-1 "Xtro\gns, Xtro\sulf2, Xtro\arsk, Xtro\sulf1" "Mmus\Arsk, Mmus\Gns, Mmus\Sulf1, Mmus\Sulf2" "Hsap\SULF2, Hsap\SULF1, Hsap\GNS, Hsap\ARSK" FBgn0037627 CG13318 - http://flybase.org/reports/FBgn0037627 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SPH101, c-SPH101, CG13318, Dmel_CG13318" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG13318 11-Aug-17 DroID_v2017_08 Drer\f7 - Cele\try-1 - - "Hsap\F9, Hsap\PLG" "viable,fertile" FBgn0021972 l(2)k10001 lethal (2) k10001 http://flybase.org/reports/FBgn0021972 - gene - - - l(2)k10001 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053087 LRP1 LDL receptor protein 1 http://flybase.org/reports/FBgn0053087 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" - cytosol ; GO:0005829 | inferred from direct assay "CG8706, CT9297, CG30368, LDLR, LRP1, lrp1, CG33087, Dm CG33087" "IPR000033:LDLR class B repeat, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR000742:EGF-like domain, IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR001881:EGF-like calcium-binding domain, IPR011042:Six-bladed beta-propeller, TolB-like, IPR009030:Growth factor receptor cysteine-rich domain, IPR013032:EGF-like, conserved site" CG33087 11-Aug-17 DroID_v2017_08 "Drer\sorl1, Drer\scospondin, Drer\lrp1bb, Drer\lrp8, Drer\lrp2b, Drer\nid1a, Drer\ldlra, Drer\lrp1aa, Drer\LOC100536757, Drer\si:dkey-258f14.3, Drer\lrp1ba, Drer\lrp5, Drer\lrp2a, Drer\ldlrad3, Drer\lrp1ab" "Scer\APM2, Scer\APM1, Scer\APM3" "Cele\lrp-1, Cele\F44E2.4, Cele\lrp-2" "Xtro\sorl1, Xtro\lrp4, Xtro\lrp2, Xtro\lrp1" "Mmus\Lrp2, Mmus\Sorl1, Mmus\Nid1, Mmus\Lrp6, Mmus\Cd320, Mmus\Lrp5, Mmus\Sspo, Mmus\Nid2, Mmus\Lrp1, Mmus\Lrp4, Mmus\Lrp1b, Mmus\Lrp3" "Hsap\LRP5L, Hsap\LRP6, Hsap\LRP5, Hsap\LRP4, Hsap\LRP1B, Hsap\SORL1, Hsap\CD320, Hsap\NID2, Hsap\LRP1, Hsap\LRP2, Hsap\NID1, Hsap\LRP3" "viable,fertile" FBgn0085208 CG34179 - http://flybase.org/reports/FBgn0085208 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34179 - CG34179 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033137 Tsp42Ep Tetraspanin 42Ep http://flybase.org/reports/FBgn0033137 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG4471, Dm.Tsp42Ep, Tsp42Ep" "IPR008952:Tetraspanin, EC2 domain, IPR018499:Tetraspanin/Peripherin" CG4471 11-Aug-17 DroID_v2017_08 "Drer\zgc:113223, Drer\tspan33a, Drer\tspan33b" - "Cele\tsp-7, Cele\tsp-16" Xtro\cd63 "Mmus\Cd63, Mmus\Tspan33, Mmus\Tspan32" "Hsap\TSPAN33, Hsap\TSPAN32, Hsap\CD63" "viable,fertile,visible" trichogen cell DRSC06871 E -0.814941855 0.392695217 1.690089221 -0.425865251 0.511134948 0.403554274 FBgn0260472 CG13673 - http://flybase.org/reports/FBgn0260472 protein_coding_gene - - - CG13673 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265953 CR44740 - http://flybase.org/reports/FBgn0265953 non_protein_coding_gene - - - CR44740 - CR44740 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037890 CG17734 - http://flybase.org/reports/FBgn0037890 protein_coding_gene - behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype - "BcDNA:RH54117, CG17734" "IPR007667:Hypoxia induced protein, domain" CG17734 11-Aug-17 DroID_v2017_08 "Drer\higd2a, Drer\higd1a" "Scer\CRG1, Scer\RCF1" Cele\T20D3.6 "Xtro\higd2a, Xtro\higd1c, Xtro\higd1a, Xtro\higd1b" "Mmus\Higd1c, Mmus\Higd1a, Mmus\Higd2a, Mmus\Higd1b, Mmus\Methig1" "Hsap\HIGD1B, Hsap\CCDC13, Hsap\HIGD2A, Hsap\HIGD1C, Hsap\HIGD1A, Hsap\METTL7A" "viable,fertile,hyperactive,conditional,chemical resistant" FBgn0260598 2L2845 - http://flybase.org/reports/FBgn0260598 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2845 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0015883 anon-64Be anon-64Be http://flybase.org/reports/FBgn0015883 - gene - - - anon-64Be - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult head

FBgn0065419 l(2)SH1529 lethal (2) SH1529 http://flybase.org/reports/FBgn0065419 gene - - - "l(2)SH1529, l(2)SH2 1529" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004902 Lrr70C Leucine-repeat-protein-70C http://flybase.org/reports/FBgn0004902 - gene - - - Lrr70C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030451 CG15717 - http://flybase.org/reports/FBgn0030451 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR016161 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR016161 - CG15717 "IPR016161:Aldehyde/histidinol dehydrogenase, IPR009961:Protein of unknown function DUF1487" CG15717 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027128 l(3)ESH2 lethal (3) ESH2 http://flybase.org/reports/FBgn0027128 - gene - - - l(3)ESH2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263947 BG00757 - http://flybase.org/reports/FBgn0263947 gene - - - BG00757 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0266209 CR44904 - http://flybase.org/reports/FBgn0266209 non_protein_coding_gene - - - CR44904 - CR44904 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060803 l(3)SzB90Cl lethal (3) SzB90Cl http://flybase.org/reports/FBgn0060803 gene - - - "0569/16, l(3)S056916b, l(3)SzB90Cl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267115 CR45555 - http://flybase.org/reports/FBgn0267115 non_protein_coding_gene - - - CR45555 - CR45555 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020801 ms(3)D185 ms(3)D185 http://flybase.org/reports/FBgn0020801 - gene - - - "3-D185, ms(3)D185" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,chemical sensitive" FBgn0002394 l(3)93Fa lethal (3) 93Fa http://flybase.org/reports/FBgn0002394 - gene - - - "er17, l(3)er17, l(3)93Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060615 l(3)S089814b lethal (3) S089814b http://flybase.org/reports/FBgn0060615 gene - - - "0898/14, l(3)S089814b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263543 mir-4979 mir-4979 stem loop http://flybase.org/reports/FBgn0263543 miRNA_gene - - - "mir-4979, dme-mir-4979, CR43528" - CR43528 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045056 fs(1)186 female sterile (1) 186 http://flybase.org/reports/FBgn0045056 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)186 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile follicle cell FBgn0052833 CG32833 - http://flybase.org/reports/FBgn0052833 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "SPH196, CG9898, CG30331, BcDNA:GH11992, CG32833" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG32833 11-Aug-17 DroID_v2017_08 "Drer\zgc:163025, Drer\proca, Drer\prozb, Drer\proza, Drer\si:ch211-165b19.9" - - - "Mmus\Prss29, Mmus\Proc, Mmus\Proz" "Hsap\PROZ, Hsap\KLK5, Hsap\PROC" "viable,visible" trichogen cell FBgn0010836 l(3)04220 lethal (3) 04220 http://flybase.org/reports/FBgn0010836 FBgn0011435 gene - - - "l(3)j11E7, l(3)04220" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262728 Pal2 Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 2 http://flybase.org/reports/FBgn0262728 protein_coding_gene peptidylamidoglycolate lyase activity ; GO:0004598 | inferred from direct assay peptidylamidoglycolate lyase activity ; GO:0004598 | inferred from mutant phenotype cellular metabolic process ; GO:0044237 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay "CG5472, PAL2, dPAL2, Pal2, PAL, anon-WO0149856.5, Pal" "IPR011042:Six-bladed beta-propeller, TolB-like, IPR013017:NHL repeat, subgroup, IPR001258:NHL repeat" CG5472 11-Aug-17 DroID_v2017_08 Drer\pam - "Cele\pghm-1, Cele\pgal-1, Cele\pamn-1" Xtro\pam "Mmus\Nhlrc3, Mmus\Pam" "Hsap\NHLRC3, Hsap\PAM" FBgn0031498 CG17260 - http://flybase.org/reports/FBgn0031498 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17260 "IPR001841:Zinc finger, RING-type, IPR006575:RWD domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17260 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261393 alpha-Est5 alpha-Esterase-5 http://flybase.org/reports/FBgn0261393 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay - - "alpha-Est5, DmalphaE5, ESTC, alphaE5, aE5, D, CG1089, EST9, Est-c, EST-C, Est-9, Est-C, EstC" "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG1089 11-Aug-17 DroID_v2017_08 "Drer\nlgn4b, Drer\nlgn1, Drer\cel.1, Drer\si:ch211-93f2.1, Drer\cell, Drer\ces2, Drer\ces3, Drer\LOC100334697, Drer\nlgn4a, Drer\nlgn2a, Drer\nlgn3a, Drer\nlgn2b, Drer\nlgn3b" - "Cele\C17H12.4, Cele\T28C12.4, Cele\F07C4.12, Cele\F56C11.6, Cele\K11G9.2, Cele\F15A8.6, Cele\F13H6.3, Cele\C52A10.1, Cele\K11G9.3, Cele\T28C12.5, Cele\B0238.7, Cele\K11G9.1, Cele\Y71H2AM.13, Cele\T07H6.1, Cele\K07C11.4, Cele\R173.3, Cele\B0238.1" "Xtro\nlgn2, Xtro\LOC100494782, Xtro\cel, Xtro\ces2, Xtro\nlgn4x, Xtro\ces3, Xtro\nlgn3" "Mmus\Nlgn2, Mmus\Ces5a, Mmus\Ces1b, Mmus\Ces2e, Mmus\Ces4a, Mmus\Ces2g, Mmus\Ces1d, Mmus\Ces1g, Mmus\Ces2f, Mmus\Nlgn3, Mmus\Nlgn1, Mmus\Ces1f, Mmus\Ces1h, Mmus\Ces3b, Mmus\Ces3a, Mmus\Ces1e, Mmus\Ces2a, Mmus\Ces2c, Mmus\Cel, Mmus\Ces1c, Mmus\Ces2h, Mmus\Ces2b" "Hsap\CES1, Hsap\NLGN3, Hsap\CEL, Hsap\NLGN1, Hsap\NLGN4Y, Hsap\CES4A, Hsap\CES2, Hsap\NLGN4X, Hsap\CES5A, Hsap\NLGN2, Hsap\CES3" FBgn0027110 ms(2)RK2 ms(2)RK2 http://flybase.org/reports/FBgn0027110 - gene - - - ms(2)RK2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0015808 ScpX Sterol carrier protein X-related thiolase http://flybase.org/reports/FBgn0015808 FBgn0032716 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002155, InterPro:IPR020613, InterPro:IPR020615, InterPro:IPR020616, InterPro:IPR020617 phospholipid transporter activity ; GO:0005548 | inferred from sequence or structural similarity with UniProtKB:P22307" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002155, InterPro:IPR016039, InterPro:IPR020613, InterPro:IPR020615, InterPro:IPR020616, InterPro:IPR020617 phospholipid transport ; GO:0015914 | inferred from sequence or structural similarity with UniProtKB:P22307" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P22307 peroxisome ; GO:0005777 | inferred from sequence model lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P22307 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with UniProtKB:P22307 "CG17320, ScpX" "IPR003033:SCP2 sterol-binding domain, IPR016039:Thiolase-like, IPR020613:Thiolase, conserved site, IPR020615:Thiolase, acyl-enzyme intermediate active site, IPR020616:Thiolase, N-terminal, IPR020617:Thiolase, C-terminal, IPR002155:Thiolase" CG17320 11-Aug-17 DroID_v2017_08 "Drer\LOC100330644, Drer\scp2b, Drer\stoml1, Drer\scp2a, Drer\hsdl2" Scer\FOX2 Cele\daf-22 "Xtro\scp2, Xtro\rsbn1, Xtro\rsbn1l, Xtro\stoml1, Xtro\hsdl2" "Mmus\Rsbn1, Mmus\Stoml1, Mmus\Scp2, Mmus\Hsdl2, Mmus\Scp2d1, Mmus\Rsbn1l" "Hsap\CTDSP2, Hsap\RSBN1L, Hsap\SCP2D1, Hsap\STOML1, Hsap\HSDL2, Hsap\SCP2" viable FBgn0058469 CR40469 - http://flybase.org/reports/FBgn0058469 non_protein_coding_gene - - - CR40469 - CR40469 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022729 l(2)PGM-45 lethal (2) PGM-45 http://flybase.org/reports/FBgn0022729 - gene - - - "PGM-45, l(2)PGM-45" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265872 CR44661 - http://flybase.org/reports/FBgn0265872 non_protein_coding_gene - - - "lincRNA.996, CR44661" - CR44661 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003605 Su(var)3-14 Suppressor of variegation 3-14 http://flybase.org/reports/FBgn0003605 - gene - - - "Su-var(3)14, Su(var)3-14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0259794 sinah sina homologue http://flybase.org/reports/FBgn0259794 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR013010, InterPro:IPR013323 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O77291 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10857 zinc ion binding ; GO:0008270 | inferred from sequence model" "ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR004162, InterPro:IPR018121 regulation of R7 cell differentiation ; GO:0045676 | inferred from sequence or structural similarity with UniProtKB:P21461 proteasomal protein catabolic process ; GO:0010498 | inferred from direct assay sensory organ development ; GO:0007423 | inferred from sequence or structural similarity with UniProtKB:P21461" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P21461 "CG13030, sina-h, sinah, SinaH, anon-WO0140519.228" "IPR018121:Seven-in-absentia protein, TRAF-like domain, IPR001841:Zinc finger, RING-type, IPR004162:E3 ubiquitin-protein ligase SIN-like, IPR008974:TRAF-like, IPR013010:Zinc finger, SIAH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13030 11-Aug-17 DroID_v2017_08 "Drer\siah2l, Drer\siah1, Drer\cyhr1" Scer\QDR1 "Cele\siah-1, Cele\mes-4" "Xtro\siah2, Xtro\siah1" "Mmus\Cyhr1, Mmus\Siah1a, Mmus\Siah3, Mmus\6330408A02Rik, Mmus\Trim50, Mmus\Siah2, Mmus\Siah1b" "Hsap\TRAF6, Hsap\SIAH1, Hsap\CYHR1, Hsap\TRAF3, Hsap\ADAM2, Hsap\TRIM50, Hsap\SIAH3, Hsap\TRAF4, Hsap\TRAF5, Hsap\C19orf68, Hsap\SIAH2" DRSC22181 E -0.196175672 -0.162330458 -1.797217815 -0.170535057 1.380275235 0.165849511 FBgn0083962 CG34126 - http://flybase.org/reports/FBgn0083962 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31653, CG3805, CG34126, Dm_2L:23546, Dm_2L:23517" "IPR026728:UHRF1-binding protein 1-like, IPR026854:Vacuolar protein sorting-associated protein 13, N-terminal domain" CG34126 11-Aug-17 DroID_v2017_08 "Drer\uhrf1bp1l, Drer\uhrf1bp1" - Cele\C44H4.4 "Xtro\uhrf1bp1l, Xtro\uhrf1bp1" "Mmus\Uhrf1bp1, Mmus\Uhrf1bp1l" "Hsap\UHRF1BP1, Hsap\UHRF1BP1L" "viable,fertile,visible" trichogen cell FBgn0033508 Obp46a Odorant-binding protein 46a http://flybase.org/reports/FBgn0033508 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG12905, Obp46a, DmelObp46a" - CG12905 11-Aug-17 DroID_v2017_08 "Drer\kcnt2, Drer\LOC565691, Drer\kcnt1" - - Xtro\kcnt2 "Mmus\Kcnt2, Mmus\Kcnt1" "Hsap\KCNT1, Hsap\KCNT2" viable FBgn0030660 CG8097 - http://flybase.org/reports/FBgn0030660 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR008909, InterPro:IPR009080 arginine-tRNA ligase activity ; GO:0004814 | inferred from electronic annotation with InterPro:IPR008909" arginyl-tRNA aminoacylation ; GO:0006420 | inferred from electronic annotation with InterPro:IPR008909 - CG8097 "IPR008909:DALR anticodon binding, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding" CG8097 11-Aug-17 DroID_v2017_08 "Drer\rars, Drer\dalrd3, Drer\rars2" "Scer\YDR341C, Scer\MSR1" - "Xtro\rars, Xtro\dalrd3, Xtro\rars2" "Mmus\Rars2, Mmus\Rars, Mmus\Dalrd3" "Hsap\RARS, Hsap\RARS2, Hsap\DALRD3" "viable,fertile" FBgn0067320 C75 C75 http://flybase.org/reports/FBgn0067320 gene - - - C75 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,viable" chaeta FBgn0052773 CR32773 - http://flybase.org/reports/FBgn0052773 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32773, CR32773" - CR32773 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069153 mcl(3)Z3298 mcl(3)Z3298 http://flybase.org/reports/FBgn0069153 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3298 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0005709 l(1)TK112 lethal (1) TK112 http://flybase.org/reports/FBgn0005709 - gene - - - "l112, l(1)TK112" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0033168 CG11145 - http://flybase.org/reports/FBgn0033168 protein_coding_gene - - - "BcDNA:AT20622, CG11145" - CG11145 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0082990 snoRNA:Psi28S-2263 snoRNA:Psi28S-2263 http://flybase.org/reports/FBgn0082990 snoRNA_gene - - - "snoRNA:Psi28S-2263, psi28s-2263, CR34568" - CR34568 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052364 tut tumorous testis http://flybase.org/reports/FBgn0052364 protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay negative regulation of translation ; GO:0017148 | inferred from mutant phenotype male germline stem cell symmetric division ; GO:0098730 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "anon-WO0118547.705, CG32364, tut" IPR000504:RNA recognition motif domain CG32364 11-Aug-17 DroID_v2017_08 - - Cele\hrp-2 - - - viable FBgn0035012 CG13590 - http://flybase.org/reports/FBgn0035012 protein_coding_gene - - - CG13590 IPR010512:Protein of unknown function DUF1091 CG13590 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - viable DRSC04226 IE -1.560772141 0.960863464 -1.906118885 -2.422774858 -0.452955198 0.133985831 FBgn0015490 l(2)46Cn lethal (2) 46Cn http://flybase.org/reports/FBgn0015490 - gene - - - "X, l(2)46Cn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0085703 CG41577 - http://flybase.org/reports/FBgn0085703 protein_coding_gene - - - CG41577 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040696 CG18675 - http://flybase.org/reports/FBgn0040696 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG18675 IPR021298:Protein of unknown function DUF2870 CG18675 11-Aug-17 DroID_v2017_08 Drer\c10h21orf59 - - Xtro\c21orf59 Mmus\1110004E09Rik "Hsap\C21orf59, Hsap\TCP10L" "viable,fertile" FBgn0034854 Golgin245 Golgin-245 http://flybase.org/reports/FBgn0034854 protein_coding_gene "ADP-ribosylation factor binding ; GO:0030306 | inferred from physical interaction with Arl1 protein homodimerization activity ; GO:0042803 | inferred from sequence model Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2, Rab30" "protein targeting to Golgi ; GO:0000042 | inferred from electronic annotation with InterPro:IPR000237 sleep ; GO:0030431 | inferred from expression pattern Golgi vesicle transport ; GO:0048193 | inferred by curator from GO:0000138,GO:0017137" Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi trans cisterna ; GO:0000138 | inferred from direct assay "dGolgin245, dGolgin-245, CG3493, Golgin245" IPR000237:GRIP domain CG3493 11-Aug-17 DroID_v2017_08 "Drer\golga4, Drer\znf185, Drer\golgb1, Drer\cenpe" "Scer\MLP2, Scer\USO1, Scer\MLP1" "Cele\che-10, Cele\golg-4, Cele\F59A2.2, Cele\anc-1" Xtro\golga4 "Mmus\Golga4, Mmus\Golgb1, Mmus\Cenpe, Mmus\Cenpf" "Hsap\GOLGA4, Hsap\GOLGB1, Hsap\CENPE, Hsap\CENPF" viable FBgn0022975 snRNP105K snRNP105K http://flybase.org/reports/FBgn0022975 - gene - - - "105K, snRNP105K" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262222 mir-971 mir-971 stem loop http://flybase.org/reports/FBgn0262222 miRNA_gene - - - "dme-mir-971, mir-971, MIR-971, CR42929, miR-971" - CR42929 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "eye,wing vein,wing" FBgn0020807 mfs(3)D83 mfs(3)D83 http://flybase.org/reports/FBgn0020807 - gene - - - "3-D83, mfs(3)D83" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile,chemical sensitive" FBgn0002491 l(3)SG51 lethal (3) SG51 http://flybase.org/reports/FBgn0002491 - gene - - - l(3)SG51 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0004992 cld cloudy http://flybase.org/reports/FBgn0004992 - gene - - - cld - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,female semi-sterile,male sterile" wing FBgn0259439 C607 - http://flybase.org/reports/FBgn0259439 gene - - - C607 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0267721 CR46054 - http://flybase.org/reports/FBgn0267721 non_protein_coding_gene - - - CR46054 - CR46054 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267551 CR45891 - http://flybase.org/reports/FBgn0267551 non_protein_coding_gene - - - CR45891 - CR45891 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026878 CG4325 - http://flybase.org/reports/FBgn0026878 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1096377 zinc ion binding ; GO:0008270 | inferred from sequence model regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from sequence or structural similarity with MGI:MGI:1096377 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:1096377 cellular_component ; GO:0005575 | no biological data available "EG:22E5.12, CG4325" "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4325 11-Aug-17 DroID_v2017_08 "Drer\rnf215, Drer\rnf126, Drer\rlim, Drer\zswim2, Drer\traip, Drer\rnf38, Drer\pja2, Drer\rnf24, Drer\rnf150a, Drer\znrf3, Drer\rnf111, Drer\si:ch211-81a5.1, Drer\wu:fb39e10, Drer\rnf32, Drer\rnf11b, Drer\rnf130, Drer\rnf44, Drer\rnf150, Drer\rnf165b, Drer\rnf11a, Drer\rnf165a, Drer\rnf6, Drer\zgc:175214, Drer\si:ch1073-392o20.1, Drer\rnf103, Drer\rnf115, Drer\si:dkey-51a16.9" "Scer\YBR062C, Scer\ASR1" Cele\ZK637.14 "Xtro\rlim, Xtro\rnf149, Xtro\rnf44, Xtro\rnf24, Xtro\rnf32, Xtro\rnf38, Xtro\rnf126, Xtro\pja2, Xtro\rnf181, Xtro\znrf3, Xtro\rnf115, Xtro\chmp3, Xtro\rnf11, Xtro\rnf111, Xtro\rnf11.2, Xtro\traip" "Mmus\Znrf3, Mmus\Rnf165, Mmus\Rnf6, Mmus\Rnf126, Mmus\Pja1, Mmus\Pja2, Mmus\Rnf38, Mmus\Rnf150, Mmus\Rnf111, Mmus\Rnf44, Mmus\Rnf11, Mmus\Traip, Mmus\Rnf122, Mmus\Rnf32, Mmus\Ttc3, Mmus\4930595M18Rik, Mmus\Rnf215, Mmus\Rnf130, Mmus\Rnf43, Mmus\Zswim2, Mmus\Rnf149, Mmus\Rlim, Mmus\Rnf181, Mmus\Rnf103, Mmus\Rnf24, Mmus\Rnf115" "Hsap\ZNRF3, Hsap\RNF130, Hsap\RNF44, Hsap\TTC3, Hsap\RNF43, Hsap\ZSWIM2, Hsap\RNF103, Hsap\RNF24, Hsap\PJA1, Hsap\RNF150, Hsap\CHMP3, Hsap\RNF165, Hsap\RNF32, Hsap\PJA2, Hsap\RNF126, Hsap\RNF11, Hsap\RNF6, Hsap\RNF122, Hsap\RNF215, Hsap\RNF38, Hsap\RNF149, Hsap\RNF111, Hsap\RNF115, Hsap\RLIM, Hsap\RNF181" lethal FBgn0011162 l(1)Q244 lethal (1) Q244 http://flybase.org/reports/FBgn0011162 FBgn0010210 gene - - - l(1)Q244 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003144 pratf pratfall http://flybase.org/reports/FBgn0003144 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "prat, pratf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic segment,maternal effect,embryonic/first instar larval cuticle" FBgn0025559 anon-66Fb anon-66Fb http://flybase.org/reports/FBgn0025559 - gene - - - anon-66Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019830 colt congested-like trachea http://flybase.org/reports/FBgn0019830 - protein_coding_gene carnitine:acyl carnitine antiporter activity ; GO:0005476 | inferred from biological aspect of ancestor with PANTHER:PTN001183376 carnitine:acyl carnitine antiporter activity ; GO:0005476 | inferred from sequence or structural similarity with UniProtKB:O43772 carnitine transmembrane transporter activity ; GO:0015226 | inferred from biological aspect of ancestor with PANTHER:PTN001183376 "mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:O43772 liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype acyl carnitine transport ; GO:0006844 | inferred from sequence or structural similarity with UniProtKB:O43772 carnitine transport ; GO:0015879 | inferred from biological aspect of ancestor with PANTHER:PTN001183376 epithelial cell morphogenesis ; GO:0003382 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype carnitine transport ; GO:0015879 | inferred from sequence or structural similarity with UniProtKB:O43772" mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001183376 integral component of membrane ; GO:0016021 | inferred from sequence model mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:O43772 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG3057, colt" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG3057 11-Aug-17 DroID_v2017_08 "Drer\LOC100329459, Drer\slc25a45, Drer\slc25a15a, Drer\slc25a48, Drer\slc25a47a, Drer\si:dkey-150i13.2, Drer\slc25a15b, Drer\slc25a47b, Drer\slc25a20" "Scer\YMC2, Scer\YMC1, Scer\CRC1" "Cele\dif-1, Cele\slc-25A29, Cele\T10F2.2, Cele\R07B7.10" "Xtro\slc25a20, Xtro\slc25a47, Xtro\slc25a15, Xtro\slc25a45, Xtro\slc25a48, Xtro\slc25a29, Xtro\slc25a20.2" "Mmus\Slc25a20, Mmus\Slc25a2, Mmus\Slc25a29, Mmus\Slc25a15, Mmus\Slc25a47, Mmus\Slc25a45, Mmus\Slc25a48" "Hsap\SLC25A20, Hsap\SLC25A47, Hsap\SLC25A45, Hsap\SLC25A29, Hsap\SLC25A15, Hsap\SLC25A2, Hsap\SLC25A48" embryonic stage -- adult stage "partially lethal - majority die,recessive,female sterile,poor,lethal,viable" "embryonic/larval tracheal system,wing,wing vein,wing & trichome" FBgn0003436 sma smaller http://flybase.org/reports/FBgn0003436 - gene - - - sma - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,recessive,visible,viable,fertile" pigment cell FBgn0037398 CG15580 - http://flybase.org/reports/FBgn0037398 protein_coding_gene - - - CG15580 "IPR032675:Leucine-rich repeat domain, L domain-like" CG15580 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-114l13.4, Drer\si:dkey-59l11.10, Drer\si:ch211-271g18.1, Drer\si:dkey-126g1.7, Drer\si:ch211-227p7.5, Drer\si:dkey-7i4.1, Drer\si:dkey-222h21.1, Drer\si:zfos-364h11.1, Drer\si:dkey-222h21.7, Drer\si:dkey-264f17.2, Drer\si:ch73-24k9.2, Drer\si:ch211-236p5.3, Drer\si:ch211-15j1.5, Drer\nlrc3l, Drer\si:ch211-181d7.1, Drer\si:ch211-194e1.7, Drer\si:ch211-122c9.5, Drer\wu:fb15h11, Drer\LOC108183512, Drer\si:ch211-201o1.1, Drer\si:ch211-205a14.1, Drer\si:dkey-23k10.2, Drer\LOC100536116, Drer\si:dkey-27n6.1, Drer\LOC566782, Drer\LOC103910258, Drer\LOC100334715, Drer\si:ch211-108d22.2, Drer\si:dkey-222h21.6, Drer\nod1, Drer\si:ch211-66k16.28, Drer\si:ch211-171l17.4, Drer\si:dkey-222h21.11, Drer\si:rp71-7l19.2, Drer\si:dkey-222h21.9, Drer\si:ch211-255g12.8, Drer\si:dkeyp-123a12.2, Drer\zgc:194906, Drer\si:dkey-121n8.7, Drer\si:ch211-236p5.2, Drer\si:ch211-66k16.2, Drer\si:dkey-3h2.3, Drer\zgc:174180, Drer\si:ch211-114l13.1, Drer\si:ch211-194e1.9, Drer\zmp:0000001020, Drer\si:ch211-214b16.3, Drer\si:dkey-151g22.1, Drer\LOC100003765, Drer\LOC568664, Drer\nod2, Drer\LOC560232, Drer\si:dkey-29j8.1, Drer\zgc:174944, Drer\si:ch211-232d10.1, Drer\nlrx1, Drer\si:ch211-114l13.13, Drer\si:ch211-149a19.3, Drer\LOC101884586, Drer\si:ch211-278p9.2, Drer\si:dkey-222h21.5, Drer\si:ch211-196h16.5, Drer\si:dkeyp-35e5.5, Drer\si:dkey-222h21.2, Drer\si:ch211-196h16.4, Drer\LOC100150280, Drer\si:ch211-22k7.9, Drer\si:dkey-118k5.3, Drer\si:dkey-233e3.2, Drer\si:dkeyp-15a6.2, Drer\si:dkey-17e16.8, Drer\si:dkey-222h21.4, Drer\si:dkey-222h21.8, Drer\si:dkey-13n15.11, Drer\si:ch211-191a16.2, Drer\si:ch211-181d7.3, Drer\nlrb5, Drer\tcte1, Drer\LOC101883625, Drer\si:ch211-238e22.8, Drer\si:ch211-197e7.1, Drer\si:dkey-11n14.1, Drer\si:ch211-15j1.1, Drer\ciita, Drer\si:dkeyp-4c4.1, Drer\nlrc3, Drer\LOC100537399, Drer\LOC103910107, Drer\zgc:136791, Drer\si:ch73-236c18.7, Drer\si:dkey-26m3.3, Drer\si:ch211-278p9.3, Drer\si:ch211-11p18.6, Drer\si:dkey-82i20.1, Drer\si:dkey-222h21.3, Drer\si:ch211-227e10.6, Drer\LOC100329480, Drer\LOC100536924, Drer\si:ch211-207e19.2, Drer\si:ch73-236c18.5, Drer\si:dkey-222h21.10, Drer\si:ch211-226o13.1, Drer\si:ch211-191a16.5, Drer\si:ch211-233m11.1" - - Xtro\tcte1 "Mmus\Nod1, Mmus\Nlrp6, Mmus\Nlrp1b, Mmus\Nlrp12, Mmus\Nlrp9c, Mmus\Nlrp4a, Mmus\Nlrp3, Mmus\Nlrp14, Mmus\Nlrp4e, Mmus\Nlrc3, Mmus\Nlrc5, Mmus\Nlrp4c, Mmus\Nlrp9a, Mmus\Nlrp5, Mmus\Nlrp4f, Mmus\Nod2, Mmus\Nlrp4b, Mmus\Nlrp2, Mmus\Nlrp9b, Mmus\Tcte1, Mmus\Ciita, Mmus\Nlrp4g, Mmus\Nlrp1a, Mmus\Nlrp10, Mmus\Nlrx1" "Hsap\NLRP14, Hsap\NLRP8, Hsap\NLRP9, Hsap\NOD2, Hsap\NLRP3, Hsap\NLRP13, Hsap\NLRP2, Hsap\NLRC3, Hsap\NLRP5, Hsap\NLRP7, Hsap\NLRP4, Hsap\NLRP1, Hsap\NLRP11, Hsap\NLRP12, Hsap\NLRC5, Hsap\NOD1, Hsap\TCTE1, Hsap\NLRX1, Hsap\NLRP6, Hsap\NLRP10, Hsap\CIITA" viable FBgn0011448 l(3)neo4 lethal (3) neo4 http://flybase.org/reports/FBgn0011448 - gene - - - l(3)neo4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016963 umpB uncoordinated with mechanoreceptor potential B http://flybase.org/reports/FBgn0016963 - gene - - - umpB - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038805 TFAM mitochondrial transcription factor A http://flybase.org/reports/FBgn0038805 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:Q00059" "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:Q00059 response to oxidative stress ; GO:0006979 | inferred from direct assay" mitochondrion ; GO:0005739 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q00059 centrosome ; GO:0005813 | inferred from direct assay "Tfam, d-TFAM, D-mtTFA, mttfa, d-mttfa, d-tfam, CG4217, TFAM, MTTFA, tfam, mtTFA" IPR009071:High mobility group box domain CG4217 11-Aug-17 DroID_v2017_08 "Drer\tox3, Drer\tfam, Drer\hmgb2a, Drer\hmgb1a, Drer\tox4b, Drer\hmg20b, Drer\tox, Drer\ubtf, Drer\hmgb2b, Drer\tox4a, Drer\hmgb3a, Drer\hmgb1b, Drer\hmg20a, Drer\hmgb3b, Drer\ubtfl" "Scer\NHP10, Scer\NHP6A, Scer\ABF2, Scer\NHP6B, Scer\IXR1, Scer\HMO1" "Cele\hmg-5, Cele\phf-33" "Xtro\tox3, Xtro\hmgb3, Xtro\tox2, Xtro\tox, Xtro\tox4, Xtro\hmgb1, Xtro\ubtf, Xtro\tfam, Xtro\hmg20a, Xtro\hmgb2, Xtro\hmg20b" "Mmus\Tox3, Mmus\Hmgb2, Mmus\Tfam, Mmus\Tox2, Mmus\Hmgb4, Mmus\Ubtfl1, Mmus\Ubtf, Mmus\Hmgb3, Mmus\Hmg20a, Mmus\Hmg20b, Mmus\Tox4, Mmus\Hmgb1, Mmus\Tox" "Hsap\TOX2, Hsap\HMGB4, Hsap\TOX, Hsap\HMGB2, Hsap\BHMG1, Hsap\UBTF, Hsap\TFAM, Hsap\HMG20A, Hsap\HMG20B, Hsap\TOX4, Hsap\HMGB3, Hsap\TOX3, Hsap\SP100, Hsap\HMGB1" "oxidative stress response defective,short lived,male limited,visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC15552 K -0.204648371 0.386283051 -0.962932534 -0.056733272 1.86909438 1.09655433 FBgn0038161 CG9269 - http://flybase.org/reports/FBgn0038161 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9269 - CG9269 11-Aug-17 DroID_v2017_08 - - Cele\R02F2.5 - - - FBgn0053260 CG33260 - http://flybase.org/reports/FBgn0053260 protein_coding_gene tRNA-intron endonuclease activity ; GO:0000213 | inferred from biological aspect of ancestor with PANTHER:PTN000317188 tRNA-type intron splice site recognition and cleavage ; GO:0000379 | inferred from biological aspect of ancestor with PANTHER:PTN000317188 tRNA-intron endonuclease complex ; GO:0000214 | inferred from electronic annotation with InterPro:IPR016690 cellular_component ; GO:0005575 | no biological data available "CG13470, CG33260" "IPR006677:tRNA intron endonuclease, catalytic domain-like, IPR016690:tRNA-splicing endonuclease, SEN34 subunit" CG33260 11-Aug-17 DroID_v2017_08 Drer\tsen34 Scer\SEN34 Cele\tsen-34 Xtro\tsen34 Mmus\Tsen34 Hsap\TSEN34 viable FBgn0051949 CG31949 - http://flybase.org/reports/FBgn0051949 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31949 - CG31949 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262937 Rabex-5 Rabaptin-5-associated exchange factor for Rab5 http://flybase.org/reports/FBgn0262937 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002653 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002653 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence model Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from direct assay imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype regulation of Rab protein signal transduction ; GO:0032483 | inferred from sequence model negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype positive regulation of protein ubiquitination ; GO:0031398 | inferred from direct assay regulation of endosome size ; GO:0051036 | inferred from mutant phenotype inferred from genetic interaction with Rbpn-5 regulation of Rab protein signal transduction ; GO:0032483 | inferred from direct assay endocytic vesicle ; GO:0030139 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "Rabex-5, CG9139, RabGEF1, Rabex5" "IPR002653:Zinc finger, A20-type, IPR003123:VPS9 domain" CG9139 11-Aug-17 DroID_v2017_08 "Drer\rabgef1l, Drer\zfand3, Drer\zfand5b, Drer\zfand4, Drer\zgc:77486, Drer\rabgef1, Drer\zfand6, Drer\zfand5a" "Scer\VPS9, Scer\MUK1" Cele\rabx-5 "Xtro\zfand5, Xtro\rabgef1, Xtro\zfand4, Xtro\zfand3, Xtro\zfand6" "Mmus\Zfand6, Mmus\Zfand4, Mmus\Zfand3, Mmus\Zfand5, Mmus\Rabgef1" "Hsap\RABGEF1, Hsap\ZFAND5, Hsap\ZFAND4, Hsap\ZFAND6, Hsap\ZFAND3, Hsap\RIN2, Hsap\KCTD7" FBgn0262843 CG43207 - http://flybase.org/reports/FBgn0262843 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43207, DMG8-chr2R.33.031, lincRNA.382" - CG43207 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023082 fs(2)H47 fs(2)H47 http://flybase.org/reports/FBgn0023082 - gene - - - fs(2)H47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,maternal effect" FBgn0017428 anon-67Ea anon-67Ea http://flybase.org/reports/FBgn0017428 - gene - - - anon-67Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000936 fs(2)A6 female sterile (2) A6 http://flybase.org/reports/FBgn0000936 - gene - - - fs(2)A6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0038218 CG14841 - http://flybase.org/reports/FBgn0038218 protein_coding_gene molecular_function ; GO:0003674 | no biological data available developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 cellular_component ; GO:0005575 | no biological data available "BcDNA:AT04690, CG14841" IPR007999:Protein of unknown function DUF745 CG14841 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC27235 K -0.087467526 -0.184865914 0.411936883 0.903124814 -0.487829223 -1.762705236 FBgn0030982 CG7423 - http://flybase.org/reports/FBgn0030982 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from sequence or structural similarity with RGD:619806 positive regulation of cell growth ; GO:0030307 | inferred from sequence or structural similarity with RGD:619806 nucleus ; GO:0005634 | inferred from sequence or structural similarity with RGD:619806 cytosol ; GO:0005829 | inferred from sequence or structural similarity with RGD:619806 CG7423 "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG7423 11-Aug-17 DroID_v2017_08 Drer\mtpn "Scer\MGA2, Scer\SPT23, Scer\YGL242C, Scer\YCR051W" "Cele\C43H6.3, Cele\F22G12.4" Xtro\mtpn Mmus\Mtpn "Hsap\ANKRD7, Hsap\ASB12, Hsap\LUZP6, Hsap\MTPN" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0060576 l(3)S095414 lethal (3) S095414 http://flybase.org/reports/FBgn0060576 gene - - - "0954/14, l(3)S095414" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0002716 mei-W68 meiotic W68 http://flybase.org/reports/FBgn0002716 "FBgn0022167, FBgn0050132, FBgn0065111" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR013049 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000091176 DNA topoisomerase type II (ATP-hydrolyzing) activity ; GO:0003918 | inferred from biological aspect of ancestor with PANTHER:PTN000091176 endodeoxyribonuclease activity, producing 3'-phosphomonoesters ; GO:0016889 | inferred from biological aspect of ancestor with PANTHER:PTN000091176" "DNA topological change ; GO:0006265 | inferred from electronic annotation with InterPro:IPR004085 DNA catabolic process, endonucleolytic ; GO:0000737 | inferred from electronic annotation with InterPro:IPR002815 reciprocal meiotic recombination ; GO:0007131 | traceable author statement early meiotic recombination nodule assembly ; GO:0042139 | inferred from mutant phenotype meiotic DNA double-strand break formation ; GO:0042138 | inferred from biological aspect of ancestor with PANTHER:PTN000091177 meiotic DNA double-strand break processing ; GO:0000706 | inferred from direct assay oogenesis ; GO:0048477 | inferred from genetic interaction with okr, p53 reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype late meiotic recombination nodule assembly ; GO:0042140 | inferred from mutant phenotype" nuclear chromosome ; GO:0000228 | inferred from biological aspect of ancestor with PANTHER:PTN000091177 "meiW68, W68, l(2)k05603, mei W-68, CG30132, CG7753, mei-W68, spo11, Mei-W68, MeiW68, mei, mei-w68, Spo11" "IPR002815:Spo11/DNA topoisomerase VI subunit A, IPR004085:DNA topoisomerase VI, subunit A, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR034136:Topoisomerase 6 subunit A/Spo11, TOPRIM domain, IPR013049:Spo11/DNA topoisomerase VI, subunit A, N-terminal" CG7753 11-Aug-17 DroID_v2017_08 Drer\spo11 Scer\SPO11 Cele\spo-11 Xtro\spo11 Mmus\Spo11 Hsap\SPO11 " adult stage | female , embryonic stage--P-stage , adult stage | male " " organism

, germarium region 3

, germarium region 2

, testis

" "viable,lethal,recessive,meiotic cell cycle defective,wild-type" "late recombination nodule,early recombination nodule" DRSC07649 K -0.912041242 -2.218252635 FBgn0035523 Ctl1 Choline transporter-like 1 http://flybase.org/reports/FBgn0035523 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG1311, Ctl1, DmCTL1" IPR007603:Choline transporter-like CG1311 11-Aug-17 DroID_v2017_08 "Drer\slc44a5b, Drer\slc44a1a, Drer\slc44a2, Drer\slc44a5a, Drer\slc44a1b" Scer\PNS1 - "Xtro\slc44a2, Xtro\slc44a4, Xtro\slc44a1, Xtro\slc44a5" "Mmus\Slc44a2, Mmus\Slc44a4, Mmus\Slc44a1, Mmus\Slc44a5, Mmus\Slc44a3" "Hsap\SLC44A1, Hsap\SLC44A5, Hsap\SLC44A2, Hsap\SLC44A4, Hsap\SLC44A3" viable FBgn0041164 armi armitage http://flybase.org/reports/FBgn0041164 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with fs(1)Yb inferred from physical interaction with piwi inferred from physical interaction with vret DNA helicase activity ; GO:0003678 | non-traceable author statement "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype embryonic axis specification ; GO:0000578 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype microtubule organizing center organization ; GO:0031023 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype negative regulation of DNA damage checkpoint ; GO:2000002 | inferred from genetic interaction with lok" Yb body ; GO:0070725 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay "armi, CG11513, Armi, ARMI, APC16" "IPR026127:Probable RNA helicase SDE3, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG11513 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97a13.6, Drer\helz2, Drer\mov10b.2, Drer\mov10a, Drer\mov10b.1, Drer\zgc:154086" Scer\NAM7 - "Xtro\mov10l1, Xtro\mov10, Xtro\helz" "Mmus\Helz, Mmus\Helz2, Mmus\Mov10l1, Mmus\Mov10" "Hsap\HELZ2, Hsap\MOV10, Hsap\HELZ, Hsap\MOV10L1" "female sterile,male sterile,partially,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,memory defective,recessive,fertile,viable" "egg,maternal effect,follicle cell,dorsal appendage,microtubule organizing center & oocyte,oocyte & microtubule organizing center,oocyte & microtubule" FBgn0036145 CG7607 - http://flybase.org/reports/FBgn0036145 protein_coding_gene - - - "CG7607, CT23219, BcDNA:RH68451" "IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003599:Immunoglobulin subtype" CG7607 11-Aug-17 DroID_v2017_08 - - "Cele\oig-4, Cele\oig-1" - - - "neuroanatomy defective,viable" "intersegmental nerve,anterior fascicle & synapse | supernumerary,anterior fascicle & synapse" FBgn0264255 para paralytic http://flybase.org/reports/FBgn0264255 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 sodium channel activity ; GO:0005272 | inferred from mutant phenotype voltage-gated sodium channel activity ; GO:0005248 | inferred from direct assay voltage-gated sodium channel activity ; GO:0005248 | non-traceable author statement "male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from direct assay chemical synaptic transmission ; GO:0007268 | traceable author statement response to pyrethroid ; GO:0046684 | inferred from mutant phenotype response to pyrethroid ; GO:0046684 | non-traceable author statement response to DDT ; GO:0046680 | inferred from mutant phenotype mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with kcc sodium ion transport ; GO:0006814 | non-traceable author statement response to DDT ; GO:0046680 | non-traceable author statement response to DDT ; GO:0046680 | inferred from direct assay membrane depolarization during action potential ; GO:0086010 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 sodium ion transmembrane transport ; GO:0035725 | inferred from mutant phenotype response to drug ; GO:0042493 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from direct assay male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype neuronal action potential ; GO:0019228 | inferred from biological aspect of ancestor with PANTHER:PTN000798901" "voltage-gated sodium channel complex ; GO:0001518 | inferred from electronic annotation with InterPro:IPR001696, InterPro:IPR010526, InterPro:IPR028826 integral component of plasma membrane ; GO:0005887 | inferred from direct assay plasma membrane ; GO:0005886 | non-traceable author statement" "para, DmNa[[V]], DmNav1, DmNa[[v]]1, DmNa[[v]], CG9907, sbl, olfD, l(1)ESHS48, l(1)14Da, sbl-1, Ocd, bss, bas, lincRNA.S9469, par, Nav1" "IPR024583:Voltage-gated Na+ ion channel, cytoplasmic domain, IPR001696:Voltage gated sodium channel, alpha subunit, IPR005821:Ion transport domain, IPR010526:Sodium ion transport-associated, IPR002048:EF-hand domain, IPR031649:Voltage-dependent L-type calcium channel, IQ-associated domain" CG9907 11-Aug-17 DroID_v2017_08 "Drer\cacna1ab, Drer\scn8ab, Drer\cacna1fa, Drer\cacna1da, Drer\cacna1aa, Drer\scn1a, Drer\scn8aa, Drer\cacna1sb, Drer\cacna1bb, Drer\cacna1e, Drer\cacna1sa, Drer\cacna1ba, Drer\cacna1c, Drer\scn12ab, Drer\scn1lab, Drer\cacna1eb, Drer\nalcn, Drer\scn4aa, Drer\cacna1fb, Drer\scn4ab, Drer\scn12aa" Scer\CCH1 "Cele\unc-77, Cele\egl-19, Cele\nca-2, Cele\unc-2" "Xtro\nalcn, Xtro\scn5a, Xtro\scn3a, Xtro\cacna1s, Xtro\scn4a, Xtro\cacna1f, Xtro\cacna1a, Xtro\scn1a, Xtro\scn2a" "Mmus\Cacna1f, Mmus\Scn9a, Mmus\Cacna1d, Mmus\Scn7a, Mmus\Cacna1c, Mmus\Scn4a, Mmus\Cacna1s, Mmus\Scn8a, Mmus\Cacna1a, Mmus\Nalcn, Mmus\Catsper2, Mmus\Scn3a, Mmus\Cacna1e, Mmus\Cacna1b, Mmus\Scn10a, Mmus\Scn5a, Mmus\Scn1a, Mmus\Scn11a, Mmus\Scn2a" "Hsap\SCN5A, Hsap\CACNA1S, Hsap\SCN7A, Hsap\SCN10A, Hsap\CACNA1C, Hsap\SCN2A, Hsap\SCN1A, Hsap\CACNA1F, Hsap\SCN9A, Hsap\SCN11A, Hsap\NALCN, Hsap\SCN8A, Hsap\SCN3A, Hsap\CACNA1A, Hsap\SCN4A, Hsap\CACNA1B, Hsap\CACNA1D" FBgn0061197 CG13164 - http://flybase.org/reports/FBgn0061197 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13164, Sip2, SIP2" - CG13164 11-Aug-17 DroID_v2017_08 - - Cele\myo-5 - - - "viable,fertile" FBgn0010923 l(3)07615 lethal (3) 07615 http://flybase.org/reports/FBgn0010923 - gene - - - l(3)07615 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060399 l(3)S132107b lethal (3) S132107b http://flybase.org/reports/FBgn0060399 gene - - - "1321/07, l(3)S132107b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0023129 aay astray http://flybase.org/reports/FBgn0023129 FBgn0046476 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProtKB:P78330 phosphoserine phosphatase activity ; GO:0004647 | inferred from sequence or structural similarity with UniProtKB:P78330 phosphoserine phosphatase activity ; GO:0004647 | non-traceable author statement magnesium ion binding ; GO:0000287 | inferred from sequence or structural similarity with UniProtKB:P78330 "L-serine biosynthetic process ; GO:0006564 | inferred from electronic annotation with InterPro:IPR023190 axon guidance ; GO:0007411 | inferred from mutant phenotype L-serine biosynthetic process ; GO:0006564 | non-traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype L-serine metabolic process ; GO:0006563 | inferred from sequence or structural similarity with UniProtKB:P78330 peripheral nervous system development ; GO:0007422 | traceable author statement behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern" - "0423/14, CG3705, anon-WO0172774.117, aay, astray, 24661601" "IPR023190:Phosphoserine phosphatase, domain 2, IPR023214:HAD-like domain" CG3705 11-Aug-17 DroID_v2017_08 Drer\psph Scer\SER2 Cele\Y62E10A.13 Xtro\psph Mmus\Psph Hsap\PSPH "song defective,lethal,recessive,hyperactive,conditional,chemical resistant,lethal - all die before end of P-stage,some die during pharate adult stage,viable" intersegmental nerve FBgn0052174 CG32174 - http://flybase.org/reports/FBgn0052174 protein_coding_gene molecular_function ; GO:0003674 | no biological data available ubiquinone biosynthetic process ; GO:0006744 | inferred from sequence or structural similarity with UniProtKB:O13525 ubiquinone biosynthetic process ; GO:0006744 | inferred from sequence or structural similarity with SGD:S000002612 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000308948 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:O13525 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with SGD:S000002612 "CG3877, CG32174" "IPR007715:Ubiquinone biosynthesis protein Coq4, IPR027540:Ubiquinone biosynthesis protein Coq4, eukaryotes" CG32174 11-Aug-17 DroID_v2017_08 "Drer\slc35d2, Drer\slc35d1b, Drer\slc35d1a, Drer\coq4" Scer\COQ4 Cele\coq-4 "Xtro\coq4, Xtro\slc35d1" "Mmus\Slc35d1, Mmus\Slc35d2, Mmus\Coq4" "Hsap\SLC35D2, Hsap\SLC35D1, Hsap\COQ4" FBgn0031815 frj farjavit http://flybase.org/reports/FBgn0031815 protein_coding_gene lysophospholipid acyltransferase activity ; GO:0071617 | inferred from direct assay lipid modification ; GO:0030258 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from direct assay "CT26954, Frj, frj, CG9526, MBOAT" "IPR004299:Membrane bound O-acyl transferase, MBOAT" CG9526 11-Aug-17 DroID_v2017_08 Drer\mboat7 Scer\ALE1 Cele\mboa-7 Xtro\mboat7 Mmus\Mboat7 Hsap\MBOAT7 FBgn0058463 CG40463 - http://flybase.org/reports/FBgn0058463 protein_coding_gene - - - CG40463 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024843 p68 p68 http://flybase.org/reports/FBgn0024843 - gene - - - p68 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261799 dsx-c73A doublesex cognate 73A http://flybase.org/reports/FBgn0261799 protein_coding_gene "structural constituent of chitin-based cuticle ; GO:0005214 | inferred by curator from GO:0005576,GO:0040003" chitin-based cuticle development ; GO:0040003 | inferred from expression pattern perivitelline space ; GO:0098595 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "DSC73, dsc73, dsx-c73, dsx-c73A, CG4541, CG13034, CG32159, l(3)j10E8, doublesex cognate 73A" - CG32159 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000196 bald bald http://flybase.org/reports/FBgn0000196 - gene - - - "bald, bld" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,cell autonomous" "cuticle,microchaeta" FBgn0039454 CG14247 - http://flybase.org/reports/FBgn0039454 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14247 IPR002557:Chitin binding domain CG14247 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0012009 tRNA:Val-AAC-2-4 transfer RNA:Valine-AAC 2-4 http://flybase.org/reports/FBgn0012009 "FBgn0003858, FBgn0012007, FBgn0052122, FBgn0060032" tRNA_gene GUU codon-amino acid adaptor activity ; GO:0033449 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033449 cytosol ; GO:0005829 | inferred by curator from GO:0033449 "valine tRNA, val-tRNA-4, tRNA-Val-4, tRNA[Val][[4]], AE002602.trna3-ValAAC, tRNA:V4, tRNA:V:AAC:AE002602-a, CR32122, tRNA:val4:70BCa, tRNA[Val-AAC], chr3L.trna37-ValAAC, tRNA:Val-AAC-2-4, tRNA:V4:70BCa, tRNA-Val-AAC-2-4, GUU" - CR32122 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031562 CG3604 - http://flybase.org/reports/FBgn0031562 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG3604, BcDNA:LP04037" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG3604 11-Aug-17 DroID_v2017_08 "Drer\adamts10, Drer\adamts13, Drer\spint1b, Drer\adamtsl7, Drer\tfpia, Drer\adamts18, Drer\col6a3, Drer\spint1a, Drer\tfpi2, Drer\adamts12, Drer\ambp, Drer\si:dkey-117n7.5, Drer\adamts6, Drer\spint2, Drer\paplna, Drer\col6a4a, Drer\si:dkeyp-73b11.8, Drer\paplnb" - Cele\T21D12.7 "Xtro\tfpi2, Xtro\adamts13, Xtro\spint2, Xtro\adamtsl4, Xtro\adamts12, Xtro\adamts18, Xtro\adamts16, Xtro\adamts7, Xtro\adamts17, Xtro\ambp, Xtro\adamts6, Xtro\spint1, Xtro\papln, Xtro\adamts10" "Mmus\Wfdc8, Mmus\Spint2, Mmus\Adamts6, Mmus\Col6a3, Mmus\Spint5, Mmus\Adamts12, Mmus\Spint3, Mmus\Eppin, Mmus\Papln, Mmus\Adamts17, Mmus\Adamts10, Mmus\Spint1, Mmus\Wfdc6b, Mmus\Adamtsl4, Mmus\Ambp, Mmus\Adamts16, Mmus\Spint4, Mmus\Adamts13, Mmus\Adamts19, Mmus\Thsd4, Mmus\Adamts18, Mmus\Tfpi, Mmus\Adamts7, Mmus\Wfdc6a, Mmus\Tfpi2" "Hsap\SPINT3, Hsap\WFDC6, Hsap\ADAMTS19, Hsap\TFPI2, Hsap\ADAMTS12, Hsap\ADAMTS18, Hsap\ADAMTS16, Hsap\THSD4, Hsap\PAPLN, Hsap\EPPIN-WFDC6, Hsap\WFDC8, Hsap\SPINT2, Hsap\TFPI, Hsap\ADAMTS17, Hsap\SPINT1, Hsap\SPINT4, Hsap\AMBP, Hsap\ADAMTSL4, Hsap\ADAMTS13, Hsap\ADAMTS7, Hsap\ADAMTS10, Hsap\ADAMTS6, Hsap\COL6A3" "partially lethal - majority die,some die during pupal stage,lethal,visible" "trichogen cell,mesothoracic tergum" DRSC00618 K 0.438313607 -0.71682055 -0.075709948 0.308573899 1.65510611 0.507486407 FBgn0265981 CR44760 - http://flybase.org/reports/FBgn0265981 non_protein_coding_gene - - - "lincRNA.375, CR44760" - CR44760 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032812 Hakai Hakai http://flybase.org/reports/FBgn0032812 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000336748 cadherin binding ; GO:0045296 | inferred from physical interaction with shg ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:2144842 zinc ion binding ; GO:0008270 | inferred from sequence model "protein ubiquitination ; GO:0016567 | inferred from direct assay epithelium development ; GO:0060429 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype regulation of cell adhesion ; GO:0030155 | inferred from biological aspect of ancestor with PANTHER:PTN000336748 midgut development ; GO:0007494 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:2144842 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "CG10263, hakai, Hakai" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10263 11-Aug-17 DroID_v2017_08 "Drer\cbll1, Drer\LOC100002706" - - Xtro\cbll1 Mmus\Cbll1 "Hsap\ZNF645, Hsap\CBLL1" "short lived,semi-sterile,partially lethal - majority live,lethal,recessive,germline clone,embryonic/larval segmentation phenotype" "wing,leg,mechanosensory chaeta,somatic clone,supernumerary,embryonic/first instar larval cuticle,germline clone,denticle belt,denticle,epithelium,embryonic/larval midgut primordium,terminal tracheal cell" FBgn0069926 CG41125 - http://flybase.org/reports/FBgn0069926 protein_coding_gene - - - CG41125 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065383 l(2)SH1656 lethal (2) SH1656 http://flybase.org/reports/FBgn0065383 gene - - - "l(2)SH1656, l(2)SH2 1656" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000509 anon-100Ca anon-100Ca http://flybase.org/reports/FBgn0000509 - gene - - - "dsx-c100C, anon-100Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043987 Su(rst)E218 Su(rst)E218 http://flybase.org/reports/FBgn0043987 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E218, Su(rst)E218" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0265045 Strn-Mlck Stretchin-Mlck http://flybase.org/reports/FBgn0265045 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN001491415 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from direct assay myosin light chain kinase activity ; GO:0004687 | inferred from sequence or structural similarity inferred from direct assay structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with bt inferred from sequence or structural similarity with sls myosin light chain kinase activity ; GO:0004687 | inferred from sequence or structural similarity with bt" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271 protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of cell migration ; GO:0030334 | inferred from biological aspect of ancestor with PANTHER:PTN001491415 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity regulation of cytoskeleton organization ; GO:0051493 | inferred from biological aspect of ancestor with PANTHER:PTN001491415 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" Z disc ; GO:0030018 | inferred from biological aspect of ancestor with PANTHER:PTN001491415 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG44162, Strn-mlck, Strn-Mlck, CG18255, 143736_at, A(225), CT41348, MLCK, mlck, Mlc-k, CG8304, MLCK-2, MLCK-3, MLCK-1, Mlck, BEST:GH22543, BcDNA:RH74685, strn-mlck, CG15699, Strn-MLCK, Strn/Mlck" "IPR013106:Immunoglobulin V-set domain, IPR000719:Protein kinase domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013783:Immunoglobulin-like fold, IPR017441:Protein kinase, ATP binding site, IPR013098:Immunoglobulin I-set, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG44162 11-Aug-17 DroID_v2017_08 "Drer\cd22, Drer\vwa11, Drer\LOC101884775, Drer\mylk3, Drer\lrit1b, Drer\obsl1a, Drer\lrit1a, Drer\vwa10.2, Drer\obsl1b, Drer\si:ch73-380l3.2, Drer\dscama, Drer\igfn1.4, Drer\igfn1.2, Drer\zmp:0000001289, Drer\vwa10.1, Drer\LOC100333105, Drer\LOC100333244, Drer\sdk1a, Drer\spegb, Drer\obscnb, Drer\lrit3a, Drer\kirrel3l, Drer\egflam, Drer\palld, Drer\lrit3b, Drer\zmp:0000000971, Drer\mylka, Drer\igsf9a, Drer\kirrel3b, Drer\mylk4b, Drer\ush2a, Drer\LOC101885775, Drer\hmcn1, Drer\scospondin, Drer\sc:d0284, Drer\si:ch1073-459j12.1, Drer\hmcn2, Drer\mylkb, Drer\si:ch211-171h4.5, Drer\sdk1b, Drer\ncam1b, Drer\LOC100535144, Drer\igsf9bb, Drer\kirrel3a, Drer\si:ch211-1f22.3, Drer\vwa7, Drer\itgb4, Drer\ttn.2, Drer\mylk5, Drer\nexn, Drer\ttnb, Drer\kirrelb, Drer\LOC100148735, Drer\zgc:171470, Drer\paplna, Drer\zgc:172106, Drer\LOC100006752, Drer\si:ch211-286b5.9, Drer\mylk4a, Drer\kirrela" Scer\MEK1 "Cele\ketn-1, Cele\unc-89, Cele\ttn-1, Cele\ZC373.4, Cele\him-4" "Xtro\hmcn2, Xtro\lrit3, Xtro\dscaml1, Xtro\MGC89178, Xtro\dscam, Xtro\kirrel2, Xtro\obsl1, Xtro\egflam, Xtro\mylk4, Xtro\papln, Xtro\igsf9b, Xtro\mylk, Xtro\mylk3, Xtro\hmcn1" "Mmus\Dscam, Mmus\Mylk4, Mmus\Hmcn1, Mmus\Ptk7, Mmus\Speg, Mmus\Kirrel, Mmus\Zc3h11a, Mmus\Mylk2, Mmus\Obsl1, Mmus\Egflam, Mmus\Mylk, Mmus\Ttn, Mmus\Ptprq, Mmus\Obscn, Mmus\Dscaml1, Mmus\Vwa7, Mmus\Hmcn2, Mmus\Sdk1, Mmus\Papln, Mmus\Mylk3, Mmus\Lrit1, Mmus\Kirrel2, Mmus\Kirrel3, Mmus\Nexn, Mmus\Lrit3, Mmus\Mypn, Mmus\Igsf9b" "Hsap\MYLK2, Hsap\MYLK4, Hsap\KIRREL, Hsap\LRIT1, Hsap\HMCN1, Hsap\KIRREL2, Hsap\LRIT3, Hsap\EGFLAM, Hsap\KIRREL3, Hsap\MYPN, Hsap\SDK1, Hsap\HMCN2, Hsap\USH2A, Hsap\VWA7, Hsap\MYLK3, Hsap\OBSL1, Hsap\OBSCN, Hsap\SPEG, Hsap\PTK7, Hsap\NEXN, Hsap\ZC3H11A, Hsap\DSCAM, Hsap\PAPLN, Hsap\IGFN1, Hsap\IGSF22, Hsap\IGSF9B, Hsap\MYLK, Hsap\DSCAML1, Hsap\TTN" " embryonic stage | stage >14 , adult stage , pupal stage | late , embryonic stage , embryonic stage -- adult stage " " larval muscle system

,

ubiquitous " FBgn0036447 CG17173 - http://flybase.org/reports/FBgn0036447 protein_coding_gene "transferase activity, transferring hexosyl groups ; GO:0016758 | inferred from electronic annotation with InterPro:IPR006759" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006759 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006759 "CG17173, dMGAT4-2" IPR006759:Glycosyl transferase family 54 CG17173 11-Aug-17 DroID_v2017_08 "Drer\mgat4a, Drer\mgat4b, Drer\mgat4c, Drer\zgc:154054, Drer\zgc:101663" - "Cele\str-247, Cele\str-263, Cele\str-256, Cele\str-121, Cele\str-238, Cele\str-190, Cele\str-200, Cele\str-208, Cele\str-244, Cele\str-257, Cele\str-258, Cele\str-199, Cele\str-225, Cele\str-260, Cele\str-228, Cele\B0391.3, Cele\F14H8.8, Cele\str-232, Cele\str-262, Cele\Y19D10A.1, Cele\str-240, Cele\str-217, Cele\str-226, Cele\str-255" "Xtro\mgat4a, Xtro\mgat4c, Xtro\mgat4b" "Mmus\4933406M09Rik, Mmus\Mgat4c, Mmus\Mgat4e, Mmus\Mgat4d, Mmus\Mgat4b, Mmus\Mgat4a" "Hsap\MGAT4D, Hsap\MGAT4B, Hsap\MGAT4A, Hsap\MGAT4C" viable FBgn0003433 slt slight http://flybase.org/reports/FBgn0003433 - gene - - - slt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile" macrochaeta FBgn0265698 CR44505 - http://flybase.org/reports/FBgn0265698 non_protein_coding_gene - - - "CR44505, lincRNA.349" - CR44505 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022025 l(2)k08915 lethal (2) k08915 http://flybase.net/reports/FBgn0022025.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0065320 l(2)SH1918 lethal (2) SH1918 http://flybase.org/reports/FBgn0065320 gene - - - "l(2)SH1918, l(2)SH2 1918" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002366 l(3)89Aa lethal (3) 89Aa http://flybase.org/reports/FBgn0002366 - gene - - - l(3)89Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060920 l(3)S042415 lethal (3) S042415 http://flybase.org/reports/FBgn0060920 gene - - - "0424/15, l(3)S042415" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036691 beg bad egg http://flybase.org/reports/FBgn0036691 protein_coding_gene [acyl-carrier-protein] S-malonyltransferase activity ; GO:0004314 | inferred from biological aspect of ancestor with PANTHER:PTN000104896 [acyl-carrier-protein] S-malonyltransferase activity ; GO:0004314 | inferred from sequence or structural similarity with UniProtKB:Q8IVS2 transferase activity ; GO:0016740 | inferred from sequence or structural similarity with UniProtKB:Q8IVS2 fatty acid biosynthetic process ; GO:0006633 | inferred from sequence or structural similarity with UniProtKB:Q8IVS2 fatty acid biosynthetic process ; GO:0006633 | inferred from biological aspect of ancestor with PANTHER:PTN000104896 metabolic process ; GO:0008152 | inferred from sequence or structural similarity with UniProtKB:Q8IVS2 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q8IVS2 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000862002 "beg, CG7842" "IPR014043:Acyl transferase, IPR016035:Acyl transferase/acyl hydrolase/lysophospholipase, IPR016036:Malonyl-CoA ACP transacylase, ACP-binding, IPR020801:Polyketide synthase, acyl transferase domain" CG7842 11-Aug-17 DroID_v2017_08 Drer\mcat "Scer\MCT1, Scer\FAS1, Scer\FAS2" "Cele\C41A3.1, Cele\C50D2.9" Xtro\mcat Mmus\Mcat Hsap\MCAT viable FBgn0261527 vainsB vainsB http://flybase.org/reports/FBgn0261527 protein_coding_gene - - - vainsB - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0262390 mir-303 mir-303 stem loop http://flybase.org/reports/FBgn0262390 miRNA_gene - - - "mir-303, CR42924, miR-303, Mir-303, CR33606, mIR-303, dme-mir-303" - CR42924 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,lethal,lethal - all die before end of larval stage,some die during larval stage" "wing vein,ectopic,wing,wing margin" FBgn0065345 l(2)SH1819 lethal (2) SH1819 http://flybase.org/reports/FBgn0065345 gene - - - l(2)SH1819 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266448 CG45078 - http://flybase.org/reports/FBgn0266448 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45078, CG6544" - CG45078 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029928 CG3032 - http://flybase.org/reports/FBgn0029928 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG3032 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG3032 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-208k4.2, Drer\znf507, Drer\znf648" Scer\PZF1 "Cele\Y55F3AM.14, Cele\Y5F2A.4, Cele\pzf-1, Cele\mep-1, Cele\eor-1" "Xtro\gzf1, Xtro\znf507" "Mmus\Zfp648, Mmus\Zfp868, Mmus\Zfp507, Mmus\Zfp532, Mmus\Gzf1" "Hsap\ZNF648, Hsap\ZNF507, Hsap\ZBTB24, Hsap\GZF1" FBgn0022391 Lap-6 Leucine aminopeptidase 6 http://flybase.org/reports/FBgn0022391 - gene - - - "LAP6, LAP-6, Lap-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046662 anon-38C.39 anon-38C.39 http://flybase.org/reports/FBgn0046662 gene - - - "38C.39, anon-38C.39" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030367 Cyp311a1 Cyp311a1 http://flybase.org/reports/FBgn0030367 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "311a1, CG1488, Cyp311a1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG1488 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp19a1a, Drer\cyp26a1, Drer\cyp26c1, Drer\cyp19a1b, Drer\cyp3c3, Drer\cyp46a1.2, Drer\cyp20a1, Drer\LOC100329425, Drer\cyp3c4, Drer\cyp26b1, Drer\cyp3c1, Drer\cyp4t8, Drer\cyp3c2, Drer\cyp4f3, Drer\cyp46a1.1, Drer\cyp46a1.3, Drer\cyp4v8, Drer\cyp46a1.4, Drer\cyp4v7" "Scer\ERG5, Scer\DIT2" "Cele\cyp-13A3, Cele\cyp-29A2, Cele\cyp-13A1, Cele\cyp-37B1, Cele\cyp-25A1, Cele\cyp-37A1, Cele\cyp-13A8, Cele\cyp-13A10, Cele\cyp-13A7, Cele\cyp-29A4, Cele\cyp-25A3, Cele\cyp-13A5, Cele\cyp-13A12, Cele\cyp-32A1, Cele\cyp-29A3, Cele\cyp-25A4, Cele\cyp-31A2, Cele\cyp-31A3, Cele\cyp-32B1, Cele\cyp-13A4, Cele\cyp-42A1, Cele\cyp-25A2, Cele\cyp-13A11" "Xtro\cyp4f2, Xtro\cyp26a1, Xtro\cyp4f22, Xtro\cyp19a1, Xtro\cyp20a1, Xtro\LOC100488227, Xtro\cyp4b1, Xtro\mgc108213, Xtro\cyp26b1, Xtro\cyp4v2, Xtro\cyp26c1, Xtro\LOC100487918, Xtro\cyp4b1.2" "Mmus\Cyp4f37, Mmus\Cyp4a14, Mmus\Cyp4a12a, Mmus\Cyp4f18, Mmus\Cyp4a30b, Mmus\Cyp3a59, Mmus\Cyp19a1, Mmus\Cyp4b1, Mmus\Cyp3a11, Mmus\Cyp4a31, Mmus\Cyp3a41a, Mmus\Cyp4f16, Mmus\Cyp3a57, Mmus\Cyp4x1, Mmus\Cyp3a41b, Mmus\Cyp4f17, Mmus\Cyp3a44, Mmus\Cyp4a29, Mmus\Cyp20a1, Mmus\Cyp26b1, Mmus\Cyp46a1, Mmus\Cyp4f15, Mmus\Cyp4f40, Mmus\Cyp3a13, Mmus\Cyp4v3, Mmus\Cyp26c1, Mmus\Cyp26a1, Mmus\Cyp4a10, Mmus\Cyp3a16, Mmus\Cyp3a25, Mmus\Cyp4f14, Mmus\Cyp4a32, Mmus\Cyp4a12b, Mmus\Cyp4f13, Mmus\Cyp4f39" "Hsap\CYP46A1, Hsap\CYP4A11, Hsap\CYP3A4, Hsap\CYP4Z1, Hsap\CYP4X1, Hsap\CYP26C1, Hsap\CYP4F2, Hsap\CYP19A1, Hsap\CYP4F12, Hsap\CYP26B1, Hsap\CYP4F8, Hsap\CYP20A1, Hsap\CYP4V2, Hsap\CYP4F11, Hsap\CYP3A43, Hsap\CYP3A7, Hsap\CYP4F3, Hsap\CYP4F22, Hsap\CYP4A22, Hsap\CYP4B1, Hsap\CYP3A5, Hsap\CYP26A1" lethal FBgn0001771 l(1)M42 lethal (1) M42 http://flybase.org/reports/FBgn0001771 - gene - - - l(1)M42 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0013394 anon-64Bb anon-64Bb http://flybase.org/reports/FBgn0013394 - gene - - - anon-64Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014103 anon-4Cb anon-4Cb http://flybase.org/reports/FBgn0014103 - gene - - - "T3, anon-4Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028627 l(2)00434a lethal (2) 00434a http://flybase.org/reports/FBgn0028627 gene - - - "l(2)00434, l(2)00434a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264544 CG43923 - http://flybase.org/reports/FBgn0264544 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43923 IPR031957:Domain of unknown function DUF4777 CG43923 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052460 tRNA:Glu-CTC-4-1 transfer RNA:Glutamic acid-CTC 4-1 http://flybase.org/reports/FBgn0052460 tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "CR32460, AE002647.trna2-GluCTC, tRNA:E:CTC:AE002647, chr3L.trna33-GluCTC, tRNA:Glu-CTC-4-1, tRNA:CR32460, tRNA-Glu-CTC-4-1, GAG" - CR32460 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267803 CR46128 - http://flybase.org/reports/FBgn0267803 non_protein_coding_gene - - - CR46128 - CR46128 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085484 Pdxk Pyridoxal kinase http://flybase.org/reports/FBgn0085484 protein_coding_gene pyridoxal kinase activity ; GO:0008478 | inferred from biological aspect of ancestor with PANTHER:PTN000056594 pyridoxal kinase activity ; GO:0008478 | inferred from sequence or structural similarity with HGNC:8819 pyridoxal 5'-phosphate salvage ; GO:0009443 | inferred from biological aspect of ancestor with PANTHER:PTN000056594 vitamin B6 metabolic process ; GO:0042816 | inferred from biological aspect of ancestor with PANTHER:PTN000056594 cellular response to monosaccharide stimulus ; GO:0071326 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000056594 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:O00764 "CG34455, CG4446, Pdxk, dPdxk" "IPR004625:Pyridoxine kinase, IPR013749:Pyridoxamine kinase/Phosphomethylpyrimidine kinase, IPR029056:Ribokinase-like" CG34455 11-Aug-17 DroID_v2017_08 "Drer\pdxka, Drer\pdxkb" "Scer\BUD17, Scer\BUD16" Cele\F57C9.1 Xtro\pdxk Mmus\Pdxk "Hsap\PDXK, Hsap\LOC105372824" "lethal,DNA repair defective,recessive" FBgn0031190 CG12576 - http://flybase.org/reports/FBgn0031190 protein_coding_gene - - - "anon-WO0140519.40, CG12576" - CG12576 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal - all die before end of larval stage" DRSC20621 K 0.72803654 -0.388277836 0.066494579 -0.915016098 1.661460617 -0.640906316 FBgn0001739 l(1)HM9 lethal (1) HM9 http://flybase.org/reports/FBgn0001739 - gene - - - l(1)HM9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0266696 CG45186 - http://flybase.org/reports/FBgn0266696 protein_coding_gene "actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR003128, InterPro:IPR007122 actin binding ; GO:0003779 | inferred from sequence or structural similarity" "cytoskeleton organization ; GO:0007010 | inferred from electronic annotation with InterPro:IPR003128, InterPro:IPR015628 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available "CG45186, CG42669, CG32306, CG13798, CG13797, CG16763, CG13799, CG12790, CG33231, CG33232, CG1141, c62E-11, CG16764, CG13800" "IPR007123:Gelsolin-like domain, IPR003128:Villin headpiece, IPR007122:Villin/Gelsolin, IPR029006:ADF-H/Gelsolin-like domain" CG45186 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-94b4.1, Drer\svila, Drer\svilb, Drer\si:dkeyp-57f11.2" - Cele\viln-1 Xtro\svil Mmus\Svil "Hsap\SRRM2, Hsap\SVIL" FBgn0000841 fs(1)M28 female sterile (1) M28 http://flybase.org/reports/FBgn0000841 - gene - - - fs(1)M28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0022398 Gase4 Gastric serine protease 4 http://flybase.org/reports/FBgn0022398 - gene - - - Gase4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027641 l(3)SCEI-2 lethal (3) SCEI-2 http://flybase.org/reports/FBgn0027641 - gene - - - l(3)SCEI-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067667 p55M p55M http://flybase.org/reports/FBgn0067667 gene - - - "p55, p55M" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034825 CG3215 - http://flybase.org/reports/FBgn0034825 protein_coding_gene "glycerol-3-phosphate dehydrogenase [NAD+] activity ; GO:0004367 | inferred from electronic annotation with InterPro:IPR006109, InterPro:IPR006168, InterPro:IPR017751 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR011128, InterPro:IPR017751 protein homodimerization activity ; GO:0042803 | inferred from electronic annotation with InterPro:IPR017751" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006109 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006109, InterPro:IPR006168, InterPro:IPR008927, InterPro:IPR011128, InterPro:IPR013328, InterPro:IPR017751 glycerol-3-phosphate catabolic process ; GO:0046168 | inferred from electronic annotation with InterPro:IPR011128" glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR006168 "CG3215, gpdh-2" "IPR006109:Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal, IPR006168:Glycerol-3-phosphate dehydrogenase, NAD-dependent, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR011128:Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal, IPR013328:6-phosphogluconate dehydrogenase, domain 2, IPR016040:NAD(P)-binding domain, IPR017751:Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic" CG3215 11-Aug-17 DroID_v2017_08 "Drer\gpd1l, Drer\gpd1c, Drer\gpd1a, Drer\gpd1b" "Scer\GPD1, Scer\GPD2" "Cele\gpdh-2, Cele\gpdh-1" "Xtro\gpd1, Xtro\gpd1l" "Mmus\Gpd1, Mmus\Gpd1l" "Hsap\GPD1L, Hsap\GPD1" viable FBgn0262406 let-7 let-7 http://flybase.org/reports/FBgn0262406 miRNA_gene - "regulation of development, heterochronic ; GO:0040034 | traceable author statement regulation of development, heterochronic ; GO:0040034 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from expression pattern cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype" - "let-7, dme-let-7, Let-7, CR42949, CR32968, let7, let-7-C" - CR42949 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001913 l(2)25Ab lethal (2) 25Ab http://flybase.org/reports/FBgn0001913 - gene - - - "jf9, l(2)jf9, l(2)25Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052214 CG32214 - http://flybase.org/reports/FBgn0052214 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32214 - CG32214 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024651 l(2)k08707 lethal (2) k08707 http://flybase.org/reports/FBgn0024651 - gene - - - "87/7, l(2)k08707" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267018 CR45462 - http://flybase.org/reports/FBgn0267018 non_protein_coding_gene - - - CR45462 - CR45462 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051909 CG31909 - http://flybase.org/reports/FBgn0051909 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs19e08, CG31909" - CG31909 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0023060 l(1)2Dm lethal (1) 2Dm http://flybase.org/reports/FBgn0023060 - gene - - - "C3/50.71, B2/35.2, l(1)2Dm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020260 peo pendolino http://flybase.org/reports/FBgn0020260 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "pen, peo" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267954 CR46234 - http://flybase.org/reports/FBgn0267954 non_protein_coding_gene - - - "CR46234, lincRNA.346" - CR46234 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264991 CG44142 - http://flybase.org/reports/FBgn0264991 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44142 - CG44142 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259726 CG42380 - http://flybase.org/reports/FBgn0259726 protein_coding_gene - mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from electronic annotation with InterPro:IPR034595 mitochondrion ; GO:0005739 | inferred from electronic annotation with InterPro:IPR034595 "CG42380, Dromel_CG9865_FBtr0071680_cx9c_uorf3, CG9865(uORF3)" IPR034595:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 CG42380 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024980 Syx4 Syntaxin 4 http://flybase.org/reports/FBgn0024980 - protein_coding_gene SNARE binding ; GO:0000149 | inferred from sequence or structural similarity with RGD:621019 SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 synaptic vesicle fusion to presynaptic active zone membrane ; GO:0031629 | inferred from biological aspect of ancestor with PANTHER:PTN000461527 membrane fusion ; GO:0061025 | inferred from sequence or structural similarity with RGD:621019 synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity vesicle docking ; GO:0048278 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype retrograde trans-synaptic signaling ; GO:0098917 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with RGD:621019 regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:P70452 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P70452 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 synaptic vesicle ; GO:0008021 | inferred from biological aspect of ancestor with PANTHER:PTN000461527 SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 postsynaptic membrane ; GO:0045211 | inferred from direct assay SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with RGD:621019 "syx4, Syx-4, DmSyx4, EG:95B7.1, EG:95B7.11, CG2715, Dm Syx4, Syx4, Syx" "IPR000727:Target SNARE coiled-coil homology domain, IPR010989:SNARE, IPR006011:Syntaxin, N-terminal domain" CG2715 11-Aug-17 DroID_v2017_08 "Drer\zgc:165520, Drer\stx11b.2, Drer\stx19, Drer\stx11a, Drer\stx2b, Drer\stx1b, Drer\stx1a, Drer\stx2a, Drer\stx3a, Drer\stx4, Drer\stx11b.1" "Scer\SSO2, Scer\SSO1" "Cele\syx-2, Cele\unc-64, Cele\syx-4, Cele\syx-3" "Xtro\stx2, Xtro\stx19, Xtro\stx11, Xtro\stx1a, Xtro\stx3, Xtro\LOC100494194" "Mmus\Stx1b, Mmus\Stx4a, Mmus\Stx1a, Mmus\Stx19, Mmus\Stx3, Mmus\Stx2, Mmus\Stx11" "Hsap\STX4, Hsap\STX1A, Hsap\STX19, Hsap\STX1B, Hsap\STX11, Hsap\STX2, Hsap\STX3" "behavior defective,recessive,viable" FBgn0058073 CG40073 - http://flybase.org/reports/FBgn0058073 protein_coding_gene - - - CG40073 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015446 l(1)7Fg lethal (1) 7Fg http://flybase.org/reports/FBgn0015446 - gene - - - l(1)7Fg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264955 CR44124 - http://flybase.org/reports/FBgn0264955 non_protein_coding_gene - - - CR44124 - CR44124 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267970 CR46248 - http://flybase.org/reports/FBgn0267970 non_protein_coding_gene - - - CR46248 - CR46248 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063596 CS3-4 "Calcineurin suppressor, chromosome 3, group 4" http://flybase.org/reports/FBgn0063596 gene - - - CS3-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002443 l(3)PR lethal Payne Right http://flybase.org/reports/FBgn0002443 - gene - - - l(3)PR - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034310 Nup75 Nucleoporin 75kD http://flybase.org/reports/FBgn0034310 protein_coding_gene structural constituent of nuclear pore ; GO:0017056 | inferred from sequence or structural similarity with SGD:S000003803 structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000332517 "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN000332517 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000332517 SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | inferred from sequence or structural similarity with SGD:S000003803 regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | NOT inferred from mutant phenotype" nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with SGD:S000003803 nuclear pore outer ring ; GO:0031080 | inferred from biological aspect of ancestor with PANTHER:PTN000332517 "Nup75, CG5733, nup75, Nup 75" IPR011502:Nucleoporin Nup85-like CG5733 11-Aug-17 DroID_v2017_08 Drer\nup85 Scer\NUP85 Cele\npp-2 Xtro\nup85 Mmus\Nup85 Hsap\NUP85 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0004841 TkR86C Tachykinin-like receptor at 86C http://flybase.org/reports/FBgn0004841 FBgn0015775 protein_coding_gene tachykinin receptor activity ; GO:0004995 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from direct assay tachykinin receptor activity ; GO:0004995 | inferred from physical interaction with Tk tachykinin receptor activity ; GO:0004995 | inferred from direct assay neuropeptide receptor activity ; GO:0008188 | inferred from sequence model tachykinin receptor signaling pathway ; GO:0007217 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay tachykinin receptor signaling pathway ; GO:0007217 | inferred from sequence or structural similarity inter-male aggressive behavior ; GO:0002121 | inferred from genetic interaction with TkR99D integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG6515, TAKR86C, NKD, NKD12, Nkd, NKr, Takr86C, TakR86C, TkR86C, DmNTLR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001681:Neurokinin receptor, IPR017452:GPCR, rhodopsin-like, 7TM" CG6515 11-Aug-17 DroID_v2017_08 "Drer\f2r, Drer\oxgr1a.2, Drer\si:dkey-78k11.9, Drer\oxgr1a.1, Drer\cysltr2a, Drer\oxgr1a.3, Drer\tacr2, Drer\si:ch211-184m13.4, Drer\gpr4, Drer\hcar1-2, Drer\p2ry11, Drer\si:dkey-6n21.13, Drer\tacr1a, Drer\gpr174, Drer\p2ry6, Drer\LOC564730, Drer\tacr1b, Drer\f2rl1.1, Drer\f2rl1.2, Drer\tacr3l, Drer\gpr17, Drer\gpr34b, Drer\LOC100333270, Drer\hcar1-1, Drer\gpr31, Drer\tacr3a, Drer\gpr34a" - "Cele\npr-22, Cele\srv-34, Cele\F59D12.1, Cele\tkr-1, Cele\ador-1, Cele\ZK813.5, Cele\tkr-2" "Xtro\f2rl3, Xtro\p2ry4, Xtro\lpar4, Xtro\p2ry2, Xtro\gpr174, Xtro\tacr3, Xtro\p2ry11, Xtro\p2ry10, Xtro\tacr1, Xtro\p2ry1, Xtro\LOC100497020" "Mmus\Tacr2, Mmus\P2ry6, Mmus\P2ry2, Mmus\Ccr4, Mmus\Tacr3, Mmus\Ptgdr2, Mmus\P2ry4, Mmus\F2rl1, Mmus\A630033H20Rik, Mmus\Hcar2, Mmus\Gpr174, Mmus\P2ry1, Mmus\Gpr31b, Mmus\Lpar4, Mmus\Gpr68, Mmus\Oxgr1, Mmus\Gpr33, Mmus\Gpr4, Mmus\Hcar1, Mmus\F2rl2, Mmus\Tacr1, Mmus\Gpr35, Mmus\Gpr17" "Hsap\OXER1, Hsap\OXGR1, Hsap\GPR31, Hsap\HCAR1, Hsap\CYSLTR2, Hsap\GPR68, Hsap\GPR35, Hsap\PTAFR, Hsap\SUCNR1, Hsap\TACR2, Hsap\GPR174, Hsap\CYSLTR1, Hsap\P2RY6, Hsap\C3AR1, Hsap\HCAR3, Hsap\GPR4, Hsap\P2RY1, Hsap\P2RY2, Hsap\GPR33, Hsap\CCR10, Hsap\LPAR4, Hsap\TACR3, Hsap\TACR1, Hsap\PTGDR2, Hsap\F2RL1" viable FBgn0003721 Tm1 Tropomyosin 1 http://flybase.org/reports/FBgn0003721 "FBgn0010776, FBgn0011036, FBgn0015832, FBgn0015833, FBgn0046771, FBgn0046800, FBgn0060408, FBgn0064771" protein_coding_gene actin binding ; GO:0003779 | traceable author statement structural constituent of muscle ; GO:0008307 | inferred from biological aspect of ancestor with PANTHER:PTN001059856 actin filament binding ; GO:0051015 | inferred from direct assay protein kinase binding ; GO:0019901 | inferred from physical interaction with UniProtKB:A8DYP0 kinesin binding ; GO:0019894 | inferred from physical interaction with Khc actin binding ; GO:0003779 | inferred from sequence or structural similarity pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | non-traceable author statement pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype muscle contraction ; GO:0006936 | non-traceable author statement response to hyperoxia ; GO:0055093 | inferred from mutant phenotype muscle contraction ; GO:0006936 | inferred from biological aspect of ancestor with PANTHER:PTN001059856 dendrite morphogenesis ; GO:0048813 | traceable author statement actin filament organization ; GO:0007015 | inferred from biological aspect of ancestor with PANTHER:PTN000443979 oogenesis ; GO:0048477 | traceable author statement regulation of lamellipodium assembly ; GO:0010591 | inferred from mutant phenotype sarcomere ; GO:0030017 | inferred from direct assay sarcoplasmic reticulum ; GO:0016529 | colocalizes_with inferred from direct assay investment cone ; GO:0070865 | inferred from direct assay muscle thin filament tropomyosin ; GO:0005862 | inferred from biological aspect of ancestor with PANTHER:PTN001059856 cytosol ; GO:0005829 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay "TmII, Tm, TMII, cTm, tmII, TnH, CG4898, 2299, cTM, cTmII, TnH-34, mTmII, Tmr34, Tmr33, region 3, l(3)S130510, 1305/10, l(3)s2958, l(3)02299, PmI, BcDNA:LD37158, BcDNA:SD21996, BcDNA:GH09289, Tm1, tm1, TM1, TnH-33, tropomyosin, Dm Tm1, TmH-33, TmH-34, Dm TmH33, Dm TmH34, TmH33, TmH34, DmTm1, TM, chr3R:11122272..11122408, TmH" IPR000533:Tropomyosin CG4898 11-Aug-17 DroID_v2017_08 "Drer\tpm2, Drer\tpma, Drer\tpm1, Drer\tpm4b, Drer\tpm3, Drer\tpm4a" "Scer\TPM1, Scer\TPM2" Cele\lev-11 "Xtro\tpm1, Xtro\tpm4, Xtro\tpm2" "Mmus\Tpm4, Mmus\Tpm3, Mmus\Tpm2, Mmus\Txlnb, Mmus\Tpm1" "Hsap\TPM1, Hsap\TPM4, Hsap\TPM2, Hsap\TPM3, Hsap\GOLGA6L4, Hsap\GOLGA6L10" " adult stage && oogenesis stage | stage S10-12 , embryonic stage | >3-6 hr , embryonic stage | stage 11 , embryonic stage | early , embryonic stage | stage >=13 , embryonic stage | stage 6-15 , embryonic stage | stage 13 , embryonic stage | stage 6-11 , embryonic stage | 0-6 hr " " nurse cell

, ectoderm | segmentally repeated

, follicle cell

, embryo | posterior

, embryonic cortex

, embryonic central nervous system

, anterior midgut proper primordium

, dorsal ectoderm

, ventral furrow

, cephalic furrow

, embryonic brain

, midgut constriction

, germ band

, posterior midgut proper primordium

" "sterile,germline clone,maternal effect,neuroanatomy defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,behavior defective,lethal - all die before end of larval stage,some die during larval stage,grandchildless,visible,partially lethal - majority die,some die during pupal stage" "dorsal multidendritic neuron ddaE & dendrite,dendritic arborising neuron & dendrite,border follicle cell,somatic clone,nucleus | embryonic stage 4,chromosome | embryonic stage,dorsal multidendritic neuron ddaC & dendrite | somatic clone,germline cell,maternal effect,embryonic/larval pharynx,pole cell,mesothoracic tergum" DRSC13082 IE 1.670302711 0.021977576 1.814198538 -0.873519074 -0.745466217 -0.199712242 FBgn0085741 CR40528 - http://flybase.org/reports/FBgn0085741 rRNA_gene - - - CR40528 - CR40528 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002817 ms(2)2 male sterile (2) 2 http://flybase.org/reports/FBgn0002817 - gene - - - "ms, ms(2)2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,male,fertile,female,partially" FBgn0002201 l(3)67Ae lethal (3) 67Ae http://flybase.org/reports/FBgn0002201 - gene - - - l(3)67Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,recessive" FBgn0015373 clg clootie dumpling http://flybase.org/reports/FBgn0015373 - gene - - - clg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259281 EP-500.2 - http://flybase.org/reports/FBgn0259281 gene - - - EP-500.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0031504 CG15403 - http://flybase.org/reports/FBgn0031504 protein_coding_gene - - - CG15403 IPR009688:Domain of unknown function DUF1279 CG15403 11-Aug-17 DroID_v2017_08 "Drer\fam210b, Drer\fam210aa" Scer\NAT2 Cele\Y56A3A.22 Xtro\fam210a "Mmus\Fam210b, Mmus\Fam210a" "Hsap\FAM210B, Hsap\FAM210A" viable FBgn0036085 CG6527 - http://flybase.org/reports/FBgn0036085 protein_coding_gene - - endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR016763 "BcDNA:AT13283, CG6527" "IPR016763:Vesicle-associated membrane-protein-associated protein, IPR000535:Major sperm protein (MSP) domain, IPR008962:PapD-like, IPR013783:Immunoglobulin-like fold" CG6527 11-Aug-17 DroID_v2017_08 "Drer\mospd2, Drer\vapa, Drer\vapal, Drer\vapb" "Scer\SCS2, Scer\SCS22" "Cele\R08H2.10, Cele\F54H5.3, Cele\hpo-28, Cele\vpr-1, Cele\W08E3.4, Cele\Y38F2AR.10, Cele\F42G2.5, Cele\F58E6.5, Cele\ZC196.2" Xtro\mospd2 "Mmus\Vapa, Mmus\Mospd2, Mmus\Mospd3, Mmus\Vapb" "Hsap\MOSPD3, Hsap\MOSPD2, Hsap\VAPA, Hsap\VAPB" viable FBgn0053647 CG33647 - http://flybase.org/reports/FBgn0053647 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33647 IPR010512:Protein of unknown function DUF1091 CG33647 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039313 CG11892 - http://flybase.org/reports/FBgn0039313 protein_coding_gene - - - CG11892 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG11892 11-Aug-17 DroID_v2017_08 - - "Cele\E02C12.6, Cele\dhs-27, Cele\C29F7.1, Cele\C29F7.2, Cele\F58B4.5, Cele\Y45G12C.4, Cele\nhr-246, Cele\E02C12.10, Cele\E02C12.9, Cele\C18B10.6, Cele\H37A05.2, Cele\E02C12.8, Cele\F56A4.5, Cele\H06H21.8" - - - "viable,fertile" FBgn0060932 l(3)S041608 lethal (3) S041608 http://flybase.org/reports/FBgn0060932 gene - - - "0416/08, l(3)S041608" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0083256 E(smoDN)A Enhancer of smoDN group A http://flybase.org/reports/FBgn0083256 gene - smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "Group A, E(smoDN)A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethalcell lethal,somatic clone" FBgn0013493 l(1)9PP1 lethal (1) 9PP1 http://flybase.org/reports/FBgn0013493 - gene - - - l(1)9PP1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect" "segment,germline clone" FBgn0266131 161Y - http://flybase.org/reports/FBgn0266131 gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - 161Y - - 11-Aug-17 DroID_v2017_08 - - - - - - gravitaxis defective FBgn0267071 CR45515 - http://flybase.org/reports/FBgn0267071 non_protein_coding_gene - - - CR45515 - CR45515 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264438 CR43856 - http://flybase.org/reports/FBgn0264438 non_protein_coding_gene - - - "CR43856, lincRNA.140" - CR43856 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016916 misn missensed http://flybase.org/reports/FBgn0016916 - gene - peripheral nervous system development ; GO:0007422 | traceable author statement - misn - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "neuron & peripheral nervous system,peripheral nervous system,neuron,presumptive embryonic/larval peripheral nervous system" FBgn0263548 mir-4957 mir-4957 stem loop http://flybase.org/reports/FBgn0263548 miRNA_gene - - - "mir-4957, dme-mir-4957, CR43533" - CR43533 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264258 Roc1a::Roc2 - http://flybase.org/reports/FBgn0264258 engineered_fusion_gene - - - Roc1a::Roc2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0284258 l(2)k06204 lethal (2) k06204 http://flybase.org/reports/FBgn0284258 gene - - - "l(2)k06204, l(2)k06205" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0266939 CR45390 - http://flybase.org/reports/FBgn0266939 non_protein_coding_gene - - - CR45390 - CR45390 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061075 l(3)S015110b lethal (3) S015110b http://flybase.org/reports/FBgn0061075 gene - - - "l(3)S015110, 0151/10, l(3)S015110b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0038472 CG3995 - http://flybase.org/reports/FBgn0038472 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 - - CG3995 "IPR003656:Zinc finger, BED-type, IPR013087:Zinc finger C2H2-type, IPR028002:Myb/SANT-like DNA-binding domain" CG3995 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0031082 CG17003 - http://flybase.org/reports/FBgn0031082 protein_coding_gene tubulin N-acetyltransferase activity ; GO:0019799 | inferred from biological aspect of ancestor with PANTHER:PTN000269078 regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from biological aspect of ancestor with PANTHER:PTN000269078 alpha-tubulin acetylation ; GO:0071929 | inferred from biological aspect of ancestor with PANTHER:PTN000269078 microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR007965 CG17003 "IPR007965:Gcn5-related N-acetyltransferase (GNAT) domain, ATAT-type" CG17003 11-Aug-17 DroID_v2017_08 Drer\atat1 - "Cele\mec-17, Cele\atat-2" Xtro\atat1 Mmus\Atat1 Hsap\ATAT1 "viable,body color defective" mesothoracic tergum FBgn0031323 CG5139 - http://flybase.org/reports/FBgn0031323 protein_coding_gene - - - CG5139 - CG5139 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052192 CG32192 - http://flybase.org/reports/FBgn0052192 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs33g12.y1, NEST:bs33g12, NEST:bs36a12, CG32192" - CG32192 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001444 l(1)7Cf lethal (1) 7Cf http://flybase.org/reports/FBgn0001444 - gene - - - l(1)7Cf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect,neurogenic phenotype,lethal - all die before end of larval stage,partially,rescuable maternal effect,some die during larval stage" FBgn0040064 yip2 yippee interacting protein 2 http://flybase.org/reports/FBgn0040064 protein_coding_gene acetyl-CoA C-acyltransferase activity ; GO:0003988 | inferred from biological aspect of ancestor with PANTHER:PTN000432120 acetyl-CoA C-acyltransferase activity ; GO:0003988 | inferred from sequence or structural similarity with UniProtKB:P42765 fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with UniProtKB:P42765 fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000432120 microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence model mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001052761 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P42765 "Yip2, CG4600, yip2, ACAA" "IPR002155:Thiolase, IPR016039:Thiolase-like, IPR020616:Thiolase, N-terminal, IPR020610:Thiolase, active site, IPR020613:Thiolase, conserved site, IPR020615:Thiolase, acyl-enzyme intermediate active site, IPR020617:Thiolase, C-terminal" CG4600 11-Aug-17 DroID_v2017_08 "Drer\acaa1, Drer\acat1, Drer\acaa2, Drer\LOC103910030, Drer\acat2" "Scer\ERG10, Scer\POT1" "Cele\acaa-2, Cele\kat-1, Cele\T02G5.7" "Xtro\acaa1, Xtro\acaa2, Xtro\acat1, Xtro\acat2" "Mmus\Acat3, Mmus\Acaa2, Mmus\Acaa1a, Mmus\Acaa1b, Mmus\Acat2, Mmus\Acat1" "Hsap\ACAA1, Hsap\ACAT2, Hsap\ACAT1, Hsap\ACAA2" viable FBgn0014940 anon-98Da anon-98Da http://flybase.org/reports/FBgn0014940 - gene - - - anon-98Da - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031253 CG11885 - http://flybase.org/reports/FBgn0031253 protein_coding_gene - - proteasome complex ; GO:0000502 | colocalizes_with inferred from direct assay "BcDNA:AT13539, CG11885" IPR018788:Proteasome assembly chaperone 3 CG11885 11-Aug-17 DroID_v2017_08 Drer\psmg3 - - Xtro\psmg3 Mmus\Psmg3 Hsap\PSMG3 FBgn0063923 Kaz1-ORFB Kaz1-ORFB http://flybase.org/reports/FBgn0063923 protein_coding_gene - - mitochondrion ; GO:0005739 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "ORF E, ORF D, ORF C, ORF B, CG33045, Kaz1, CG1220, Kaz1-ORFB" IPR002350:Kazal domain CG1220 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-203a12.4, Drer\si:dkey-77g12.4, Drer\si:dkey-203a12.3, Drer\si:dkey-203a12.6" - - - "Mmus\Spink14, Mmus\Spink7, Mmus\Spink11, Mmus\Spinkl, Mmus\Spink2" "Hsap\SPINK14, Hsap\SPINK9, Hsap\SPINK7" FBgn0260407 mRpS23 mitochondrial ribosomal protein S23 http://flybase.org/reports/FBgn0260407 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR019520, InterPro:IPR023611 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR019520, InterPro:IPR023611 mitochondrial translation ; GO:0032543 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR019520, InterPro:IPR023611 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement" "mRpS23, l(2)SH0272, l(2)SH2 0272, CG31842" "IPR023611:Ribosomal protein S23/S25, mitochondrial, IPR019520:Ribosomal protein S23/Rsm25, mitochondrial" CG31842 11-Aug-17 DroID_v2017_08 Drer\mrps23 - Cele\mrps-23 Xtro\mrps23 Mmus\Mrps23 Hsap\MRPS23 FBgn0005600 yemG4 yema gene 4 http://flybase.org/reports/FBgn0005600 FBgn0004042 gene - - - "yG4, yT4, yemG4" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && oogenesis stage , embryonic stage | stage >=13 , larval stage--adult stage , larval stage--pupal stage , embryonic stage | stage <6 , embryonic stage | stage <=8 , adult stage && oogenesis stage | stage S7-10B , embryonic stage | 12-18 hr , adult stage && oogenesis stage | stage S9-10B " " ovary

, embryonic proventriculus

, hindgut

, imaginal disc

, organism

, nurse cell

, central nervous system

, proventriculus

, oocyte

, spermatocyte

" FBgn0039554 CG5003 - http://flybase.org/reports/FBgn0039554 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG5003, FBXL8" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG5003 11-Aug-17 DroID_v2017_08 - - - - - Hsap\FBXL12 "viable,visible" trichogen cell FBgn0030294 Pa1 PTIP associated 1 http://flybase.org/reports/FBgn0030294 protein_coding_gene molecular_function ; GO:0003674 | no biological data available histone H3-K4 methylation ; GO:0051568 | inferred from direct assay MLL3/4 complex ; GO:0044666 | inferred from direct assay "CG11750, BcDNA:RH21749, BcDNA:RE09126, Pa1, dPA1, PA1" IPR028213:PTIP-associated protein 1 CG11750 11-Aug-17 DroID_v2017_08 Drer\pagr1 - - Xtro\pagr1 Mmus\Pagr1a Hsap\PAGR1 "viable,fertile" FBgn0040706 CG12677 - http://flybase.org/reports/FBgn0040706 protein_coding_gene - - - "BcDNA:AT09846, CG12677, DIGF-8" IPR029277:Single domain Von Willebrand factor type C domain - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265832 CR44621 - http://flybase.org/reports/FBgn0265832 non_protein_coding_gene - - - "lincRNA.986, CR44621" - CR44621 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024523 l(3)j2D5 lethal (3) j2D5 http://flybase.org/reports/FBgn0024523 - gene - - - l(3)j2D5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259423 C547 - http://flybase.org/reports/FBgn0259423 gene - - - C547 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta" FBgn0060940 l(3)S039807 lethal (3) S039807 http://flybase.org/reports/FBgn0060940 gene - - - "0398/07, l(3)S039807" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065454 l(2)SH1393 lethal (2) SH1393 http://flybase.net/reports/FBgn0065454.html gene l(2)SH2 1393 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0015952 jockey\pol jockey element pol http://flybase.org/reports/FBgn0015952 - transposable_element_gene - - - "ORF2, jockey\pol, RT, joc" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031830 COX5B Cytochrome c oxidase subunit 5B http://flybase.org/reports/FBgn0031830 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P10606 cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000012880 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProtKB:P10606 mitochondrial ATP synthesis coupled proton transport ; GO:0042776 | inferred from biological aspect of ancestor with PANTHER:PTN000012880 mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000012880" lipid particle ; GO:0005811 | inferred from direct assay mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P10606 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000012880 "Vb, anon-EST:Posey143, BcDNA:RH49324, anon-WO0118547.187, CG11015, CcO Vb, COXB, COX5B, CoVb, Cox5b, cox5B" "IPR002124:Cytochrome c oxidase, subunit Vb" CG11015 11-Aug-17 DroID_v2017_08 "Drer\zgc:86599, Drer\cox5b2, Drer\cox5b1" Scer\COX4 Cele\cco-1 "Xtro\cox5b.2, Xtro\cox5b.1" Mmus\Cox5b Hsap\COX5B "stress response defective,aging defective,lethal,RU486 conditional,developmental rate defective,female sterile,short lived,male,female,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0041627 Ku80 Ku80 http://flybase.org/reports/FBgn0041627 protein_coding_gene "hydrolase activity, acting on acid anhydrides ; GO:0016817 | inferred from electronic annotation with InterPro:IPR014893 damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR024193 telomeric DNA binding ; GO:0042162 | inferred from biological aspect of ancestor with PANTHER:PTN000288287 ATP-dependent DNA helicase activity ; GO:0004003 | inferred from sequence or structural similarity" DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR024193 telomere maintenance ; GO:0000723 | inferred from mutant phenotype cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from mutant phenotype double-strand break repair via nonhomologous end joining ; GO:0006303 | inferred from mutant phenotype "Ku70:Ku80 complex ; GO:0043564 | inferred from electronic annotation with InterPro:IPR024193 nuclear chromosome, telomeric region ; GO:0000784 | inferred from biological aspect of ancestor with PANTHER:PTN000288287" "DmKu80, KU80, BG:DS09217.6, CG18801, Ku80, Ku, ku80" "IPR005161:Ku70/Ku80, N-terminal alpha/beta, IPR006164:Ku70/Ku80 beta-barrel domain, IPR014893:Ku, C-terminal, IPR016194:SPOC-like, C-terminal domain, IPR024193:Ku80, IPR002035:von Willebrand factor, type A" CG18801 11-Aug-17 DroID_v2017_08 Drer\xrcc5 Scer\YKU80 Cele\cku-80 - Mmus\Xrcc5 "Hsap\XRCC6, Hsap\XRCC5" viable FBgn0259419 EP-643 - http://flybase.org/reports/FBgn0259419 gene - - - EP-643 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta" FBgn0031284 PGAP2 Post-GPI attachment to proteins 2 http://flybase.org/reports/FBgn0031284 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with UniProtKB:Q2ABP3 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with UniProtKB:Q2ABP3 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with UniProtKB:Q2ABP3 Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity with UniProtKB:Q2ABP3 "CG3876, PGAP2" IPR019402:Frag1/DRAM/Sfk1 CG3876 11-Aug-17 DroID_v2017_08 Drer\pgap2 Scer\CWH43 "Cele\F36H9.5, Cele\F49E12.12, Cele\tag-189, Cele\C14B9.3, Cele\ZK185.4, Cele\Y11D7A.9, Cele\T23B12.5, Cele\Y38F1A.8" Xtro\pgap2 "Mmus\Pgap2, Mmus\Cwh43" "Hsap\PGAP2, Hsap\CWH43" viable DRSC00632 K -0.205007968 -0.124357886 0.291561884 -0.028714144 -0.382654175 2.909254207 FBgn0045846 mdg1\ORF2 mdg1 element ORF2 http://flybase.org/reports/FBgn0045846 transposable_element_gene - - - mdg1\ORF2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025165 l(2)38EFf lethal (2) 38EFf http://flybase.org/reports/FBgn0025165 - gene - - - l(2)38EFf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031926 CG6739 - http://flybase.org/reports/FBgn0031926 protein_coding_gene - - - CG6739 "IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR020067:Frizzled domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG6739 11-Aug-17 DroID_v2017_08 - "Scer\APM2, Scer\APM1, Scer\APM3" - - Mmus\Cd320 Hsap\CD320 FBgn0027253 l(1)G0250 lethal (1) G0250 http://flybase.org/reports/FBgn0027253 - gene - - - l(1)G0250 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0082188 l(3)S033513 lethal (3) S033513 http://flybase.org/reports/FBgn0082188 gene - - - l(3)S033513 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable,fertile,female,recessive,female sterile,sterile" "ovary,ovariole,egg chamber" FBgn0069967 CG41040 - http://flybase.org/reports/FBgn0069967 protein_coding_gene - - - CG41040 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030688 CG8952 - http://flybase.org/reports/FBgn0030688 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP52, CG8952" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG8952 11-Aug-17 DroID_v2017_08 - - - "Xtro\tpsg1, Xtro\tpsab1" - - viable FBgn0013692 mt:tRNA:Glu-TTC mitochondrial transfer RNA:Glutamic acid-TTC http://flybase.org/reports/FBgn0013692 FBgn0002867 tRNA_gene - - - "CR34081, tRNA Glu, tRNA[Glu], mtdbD00006306, mt:tRNA:Glu-TTC, mt:tRNA:E, tRNA-glu" - CR34081 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060813 l(3)S054203b lethal (3) S054203b http://flybase.org/reports/FBgn0060813 gene - - - "0542/03, l(3)S054203b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058380 CG40380 - http://flybase.org/reports/FBgn0058380 protein_coding_gene - - - CG40380 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20764 I 1.645489539 -0.73748131 -0.088650678 -0.265914048 FBgn0011861 tRNA:Gly-GCC-1-3 transfer RNA:Glycine-GCC 1-3 http://flybase.org/reports/FBgn0011861 "FBgn0051903, FBgn0060224" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "AE002690.trna2-GlyGCC, tRNA:G:GCC:AE002690-a, CR31903, tRNA:gly3:28D, tRNA[Gly-GCC], chr2L.trna10-GlyGCC, tRNA-Gly-GCC-1-3, tRNA:Gly-GCC-1-3, tRNA:G3:28D, GGC" - CR31903 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005187 l(2)S42 lethal of Seto 42 http://flybase.org/reports/FBgn0005187 - gene - - - l(2)S42 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "eye,adult head" FBgn0044350 ftz-f1::Hr39 ftz-f1::Hr39 http://flybase.org/reports/FBgn0044350 engineered_fusion_gene - - - ftz-f1::Hr39 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262722 CR43166 - http://flybase.org/reports/FBgn0262722 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43166, CG43166, lincRNA.842, mdcds_43034" - CR43166 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039683 dmrt99B doublesex-Mab related 99B http://flybase.org/reports/FBgn0039683 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR026607 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001275" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001275, InterPro:IPR026607" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026607 "CG15504, dmrt99B" "IPR001275:DM DNA-binding domain, IPR005173:DMRTA motif, IPR009060:UBA-like, IPR026607:DMRT/protein doublesex/protein male abnormal 3" CG15504 11-Aug-17 DroID_v2017_08 "Drer\dmrt2b, Drer\dmrt3a, Drer\dmrta2, Drer\dmrt1, Drer\dmrt2a" - "Cele\dmd-3, Cele\dmd-9, Cele\dmd-4, Cele\dmd-6, Cele\dmd-5, Cele\mab-3, Cele\dmd-10, Cele\dmd-7, Cele\dmd-8" "Xtro\kank1, Xtro\dmrt3, Xtro\dmrta2, Xtro\dmrta1" "Mmus\Dmrtc1a, Mmus\Dmrt3, Mmus\Dmrta1, Mmus\Dmrt2, Mmus\Dmrt1, Mmus\Dmrtc2, Mmus\Dmrta2, Mmus\Dmrtb1, Mmus\Dmrtc1c1, Mmus\Dmrtc1c2, Mmus\Dmrtc1b" "Hsap\DMRTC1, Hsap\DMRT2, Hsap\DMRTC2, Hsap\DMRTC1B, Hsap\DMRTA2, Hsap\DMRTA1, Hsap\DMRTB1, Hsap\DMRT1, Hsap\DMRT3" FBgn0002170 l(2)Sp12 lethal (2) Sp12 http://flybase.org/reports/FBgn0002170 - gene - - - l(2)Sp12 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038109 CG11656 - http://flybase.org/reports/FBgn0038109 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.199, CG11656" - CG11656 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023534 CG17778 - http://flybase.org/reports/FBgn0023534 FBgn0062971 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR026762 molecular_function ; GO:0003674 | no biological data available cell division ; GO:0051301 | inferred from electronic annotation with InterPro:IPR026762 chromosome segregation ; GO:0007059 | inferred from electronic annotation with InterPro:IPR026762 biological_process ; GO:0008150 | no biological data available spindle microtubule ; GO:0005876 | inferred from electronic annotation with InterPro:IPR026762 condensed chromosome outer kinetochore ; GO:0000940 | inferred from electronic annotation with InterPro:IPR026762 cellular_component ; GO:0005575 | no biological data available "EG:171D11.5, BcDNA:RH02374, CG17778" IPR026762:Spindle and kinetochore-associated protein 2 CG17778 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266270 Hto-WP(3)TRG - http://flybase.org/reports/FBgn0266270 gene - - - Hto-WP(3)TRG - - 11-Aug-17 DroID_v2017_08 - - - - - - eye FBgn0001896 l(2)21Fb lethal (2) 21Fb http://flybase.org/reports/FBgn0001896 - gene - - - "l(2)neh-10, l(2)neh10, l(2)21Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058166 CG40166 - http://flybase.org/reports/FBgn0058166 protein_coding_gene - - - CG40166 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069943 CG41098 - http://flybase.org/reports/FBgn0069943 protein_coding_gene - - - CG41098 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011057 l(1)Q10 lethal (1) Q10 http://flybase.org/reports/FBgn0011057 FBgn0010210 gene - - - l(1)Q10 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005421 l(1)adl10 lethal (1) adl10 http://flybase.org/reports/FBgn0005421 - gene - - - "l(1)adl-10, l(1)adl10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0019802 l(1)02 lethal (1) 02 http://flybase.org/reports/FBgn0019802 - gene - - - l(1)02 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033932 Dh44-R1 Diuretic hormone 44 receptor 1 http://flybase.org/reports/FBgn0033932 protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000832, InterPro:IPR001879 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model diuretic hormone receptor activity ; GO:0008036 | inferred from direct assay diuretic hormone receptor activity ; GO:0008036 | inferred from sequence or structural similarity calcitonin receptor activity ; GO:0004948 | inferred from sequence or structural similarity diuretic hormone receptor activity ; GO:0008036 | inferred from physical interaction with Dh44" cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay hormone-mediated signaling pathway ; GO:0009755 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "anon-WO0170980.101, anon-WO0170980.100, DmeCG8422, DH[[44]]-R1, Dh44-R1, CG8422, DH44-R1, DH-R, Dh44R1" "IPR000832:GPCR, family 2, secretin-like, IPR001879:GPCR, family 2, extracellular hormone receptor domain, IPR002001:GPCR, family 2, diuretic hormone receptor, IPR017981:GPCR, family 2-like" CG8422 11-Aug-17 DroID_v2017_08 "Drer\ghrhra, Drer\gcgra, Drer\crhr1, Drer\adcyap1r1a, Drer\calcrla, Drer\adcyap1r1b, Drer\gipr, Drer\calcrl2, Drer\calcr, Drer\pth1ra, Drer\vipr2, Drer\si:dkeyp-4h4.1, Drer\crhr2, Drer\ghrhr2, Drer\calcrlb, Drer\pth1rb, Drer\pth2r, Drer\gcgrb, Drer\ghrhrb, Drer\vipr1b, Drer\vipr1a" - "Cele\seb-3, Cele\pdfr-1" "Xtro\pth1r, Xtro\adcyap1r1, Xtro\crhr1.2, Xtro\crhr1.1, Xtro\pth2r, Xtro\gcgr, Xtro\calcrl, Xtro\gipr, Xtro\vipr1" "Mmus\Gipr, Mmus\Pth1r, Mmus\Calcrl, Mmus\Pth2r, Mmus\Vipr1, Mmus\Calcr, Mmus\Ghrhr, Mmus\Vipr2, Mmus\Gcgr, Mmus\Glp1r, Mmus\Crhr1, Mmus\Glp2r, Mmus\Crhr2, Mmus\Adcyap1r1, Mmus\Sctr" "Hsap\VIPR1, Hsap\CALCRL, Hsap\GLP1R, Hsap\GIPR, Hsap\CALCR, Hsap\PTH2R, Hsap\CRHR1-IT1-CRHR1, Hsap\GHRHR, Hsap\GCGR, Hsap\CRHR1, Hsap\SCTR, Hsap\GLP2R, Hsap\ADCYAP1R1, Hsap\PTH1R, Hsap\VIPR2, Hsap\CRHR2" DRSC07172 E -0.357994633 -0.135183574 1.645185021 0.642298972 -0.43604201 -0.101367821 FBgn0053419 5SrRNA:CR33419 5SrRNA:CR33419 http://flybase.org/reports/FBgn0053419 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33419, 5SrRNA:CR33419" - CR33419 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069314 X-195-35 X-195-35 http://flybase.org/reports/FBgn0069314 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-195-35 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,cephalopharyngeal skeleton" FBgn0013645 mfs(3)1 mfs(3)1 http://flybase.org/reports/FBgn0013645 - gene - - - mfs(3)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile" FBgn0002245 l(3)68Cg lethal (3) 68Cg http://flybase.org/reports/FBgn0002245 - gene - - - "rsg6, l(3)rsg6, l(3)68Cg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032666 CG5758 - http://flybase.org/reports/FBgn0032666 protein_coding_gene - synaptic target recognition ; GO:0008039 | inferred from mutant phenotype - CG5758 IPR000782:FAS1 domain CG5758 11-Aug-17 DroID_v2017_08 "Drer\postna, Drer\tgfbi, Drer\postnb" Scer\YLR001C Cele\F26E4.7 - "Mmus\Postn, Mmus\Tgfbi" "Hsap\TGFBI, Hsap\POSTN" "lethal - all die before end of pupal stage,some die during pupal stage,viable" wing DRSC02889 I -1.071424404 -2.016985346 0.53185522 -0.94514155 0.516841157 0.080887305 FBgn0036973 Rbbp5 Retinoblastoma binding protein 5 http://flybase.org/reports/FBgn0036973 protein_coding_gene - histone H3-K4 methylation ; GO:0051568 | inferred from direct assay histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype Set1C/COMPASS complex ; GO:0048188 | inferred from direct assay MLL3/4 complex ; GO:0044666 | inferred from direct assay MLL1/2 complex ; GO:0044665 | inferred from sequence or structural similarity with HGNC:9888 "CG5585, dRbbp5, RBBP5, Rbbp5, rbbp5" "IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR017986:WD40-repeat-containing domain" CG5585 11-Aug-17 DroID_v2017_08 Drer\rbbp5 Scer\SWD1 Cele\rbbp-5 Xtro\rbbp5 Mmus\Rbbp5 Hsap\RBBP5 "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,female fertile" mesothoracic tergum FBgn0266467 nut - http://flybase.org/reports/FBgn0266467 gene - - - nut - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "egg chamber,germline clone" FBgn0015580 4.1 4.1 http://flybase.org/reports/FBgn0015580 - gene - - - 4.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022316 l(1)D36.5 lethal (1) D36.5 http://flybase.org/reports/FBgn0022316 - gene - - - "D36.5, l(1)D36.5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021927 l(2)k11120a lethal (2) k11120a http://flybase.net/reports/FBgn0021927.html gene l(2)k11120 11-Aug-17 DroID_v2017_08 FBgn0051924 CG31924 - http://flybase.org/reports/FBgn0051924 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 "CG5564, BcDNA:AT29272, CG31924, 21064207" "IPR023198:Phosphoglycolate phosphatase, domain 2, IPR006439:HAD hydrolase, subfamily IA, IPR023214:HAD-like domain" CG31924 11-Aug-17 DroID_v2017_08 Drer\pudp "Scer\GPP1, Scer\DOG2, Scer\YKL033W-A, Scer\DOG1, Scer\GPP2" Cele\R151.10 Xtro\pudp Mmus\Hdhd1a Hsap\PUDP viable FBgn0065893 l(2)SH0214 lethal (2) SH0214 http://flybase.org/reports/FBgn0065893 gene - - - "l(2)SH0214, l(2)SH2 0214" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260434 CG42529 - http://flybase.org/reports/FBgn0260434 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG42529 - CG42529 11-Aug-17 DroID_v2017_08 - - "Cele\C18G1.9, Cele\ZC317.6, Cele\C09H10.9, Cele\C14C11.1, Cele\Y53F4B.36" - - - FBgn0259981 l(2)34Dh lethal (2) 34Dh http://flybase.org/reports/FBgn0259981 gene - - - l(2)34Dh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0041723 rho-5 rhomboid-5 http://flybase.org/reports/FBgn0041723 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from direct assay "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR002610 sleep ; GO:0030431 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype regulation of protein secretion ; GO:0050708 | inferred from biological aspect of ancestor with PANTHER:PTN001117529 positive regulation of circadian sleep/wake cycle, wakefulness ; GO:0010841 | inferred from mutant phenotype regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from genetic interaction with Egfr inferred from genetic interaction with aos inferred from genetic interaction with spi inferred from genetic interaction with sty" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002610, InterPro:IPR022764 endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN001117529 endoplasmic reticulum ; GO:0005783 | inferred from direct assay" "Rho-related[31D10], CT17046, CG5364, CG33304, rho-5, iRhom, iRhom1" "IPR002610:Peptidase S54, rhomboid, IPR022764:Peptidase S54, rhomboid domain" CG33304 11-Aug-17 DroID_v2017_08 "Drer\rpn1, Drer\rhbdf1b, Drer\rhbdf1a" Scer\OST1 "Cele\rom-4, Cele\rom-3, Cele\ribo-1" "Xtro\rhbdf2, Xtro\rhbdf1, Xtro\rpn1" "Mmus\Rpn1, Mmus\Rhbdf2, Mmus\Rhbdf1" "Hsap\RHBDF1, Hsap\RPN1, Hsap\RHBDF2" "viable,sleep defective,recessive,fertile,lethal" FBgn0259459 C933.1 - http://flybase.org/reports/FBgn0259459 gene - - - C933.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta,ectopic" FBgn0060638 l(3)S084307b lethal (3) S084307b http://flybase.org/reports/FBgn0060638 gene - - - "0843/07, l(3)S084307b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0036986 CG5282 - http://flybase.org/reports/FBgn0036986 protein_coding_gene dipeptidase activity ; GO:0016805 | inferred from biological aspect of ancestor with PANTHER:PTN000047764 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008257 - CG5282 "IPR008257:Renal dipeptidase family, IPR032466:Metal-dependent hydrolase" CG5282 11-Aug-17 DroID_v2017_08 "Drer\dpep2, Drer\dpep1" - - "Xtro\dpep2, Xtro\dpep1" "Mmus\Dpep1, Mmus\Dpep3, Mmus\Dpep2" "Hsap\DPEP3, Hsap\DPEP1, Hsap\DPEP2" viable FBgn0065221 l(2)SH2227 lethal (2) SH2227 http://flybase.org/reports/FBgn0065221 gene - - - "l(2)SH2227, l(2)SH2 2227" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065254 l(2)SH2112 lethal (2) SH2112 http://flybase.org/reports/FBgn0065254 gene - - - "l(2)SH2112, l(2)SH2 2112" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262546 CR43100 - http://flybase.org/reports/FBgn0262546 pseudogene_attribute - - - "CG43100, CR43100" - CR43100 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052563 CG32563 - http://flybase.org/reports/FBgn0052563 protein_coding_gene - - - "CG5095, CG32563" - CG32563 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003875 tu(1)Sz tumor (1) Sz http://flybase.org/reports/FBgn0003875 - gene - - - "Tu-Sz, tu-Sz, tu(1)Sz" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive" FBgn0051047 CG31047 - http://flybase.org/reports/FBgn0051047 protein_coding_gene - - - CG31047 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001060 Fs(3)Lev Female sterile (3) Levente http://flybase.org/reports/FBgn0001060 - gene molecular_function ; GO:0003674 | no biological data available embryonic cleavage ; GO:0040016 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Lev, Fs(3)Levente, Fs(3)Sz28, Fs(3)Lev" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cleavage stage embryo,maternal effect" FBgn0043888 l(3)C80 lethal (3) C80 http://flybase.org/reports/FBgn0043888 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available l(3)C80 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003684 tetra tetraltera http://flybase.org/reports/FBgn0003684 - gene - - - "tetra, tet" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,cold sensitive" "wing,mesothoracic tergum,costal vein,wing hinge,ventral" FBgn0003442 sml small http://flybase.org/reports/FBgn0003442 - gene - - - sml - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,visible" "eye,ommatidium,wing,adult thorax & microchaeta" FBgn0001814 l(1)nc3 lethal (1) nc3 http://flybase.org/reports/FBgn0001814 - gene - - - "l(1)11523, l(1)nc3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female sterile" FBgn0001441 l(1)7Cc lethal (1) 7Cc http://flybase.org/reports/FBgn0001441 - gene - - - "EC271, l(1)7Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0067914 EP303 EP303 http://flybase.org/reports/FBgn0067914 gene - - - EP303 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0040217 fs(2)LJ25 fs(2)LJ25 http://flybase.org/reports/FBgn0040217 gene - - - fs(2)LJ25 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0037996 CG4830 - http://flybase.org/reports/FBgn0037996 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG4830 "IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site, IPR025110:AMP-binding enzyme C-terminal domain" CG4830 11-Aug-17 DroID_v2017_08 "Drer\acsbg1, Drer\acsf3" Scer\PCS60 "Cele\acs-10, Cele\mec-18, Cele\acs-14, Cele\C25G6.3, Cele\acs-9, Cele\C32E8.6, Cele\acs-6, Cele\acs-7" Xtro\acsf3 "Mmus\Acsf3, Mmus\Acsbg1" "Hsap\ACSF3, Hsap\ACSM6, Hsap\ACSBG1" viable FBgn0001950 l(2)27Dc lethal (2) 27Dc http://flybase.org/reports/FBgn0001950 - gene - - - "F, l(2)27Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051029 CG31029 - http://flybase.org/reports/FBgn0051029 protein_coding_gene - - - "CG2164, BcDNA:AT12234, CG31029" "IPR031949:Domain of unknown function DUF4776, IPR031992:Domain of unknown function DUF4788" CG31029 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260112 2L2944 - http://flybase.org/reports/FBgn0260112 gene - - - 2L2944 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0051078 CG31078 - http://flybase.org/reports/FBgn0051078 protein_coding_gene - - - CG31078 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070037 3R-66-38 3R-66-38 http://flybase.org/reports/FBgn0070037 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-66-38 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "filzkorper,germline clone,maternal effect,embryonic head" FBgn0029952 CG12689 - http://flybase.org/reports/FBgn0029952 protein_coding_gene - - - CG12689 - CG12689 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004139 l(2)43Eh lethal (2) 43Eh http://flybase.org/reports/FBgn0004139 - gene - - - l(2)43Eh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044084 E(rst)H125 E(rst)H125 http://flybase.org/reports/FBgn0044084 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H125, E(rst)H125" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0267283 CR45719 - http://flybase.org/reports/FBgn0267283 non_protein_coding_gene - - - CR45719 - CR45719 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065648 l(2)SH0742 lethal (2) SH0742 http://flybase.org/reports/FBgn0065648 gene - - - "l(2)SH0742, l(2)SH2 0742" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028001 l(3)S119715 lethal (3) S119715 http://flybase.org/reports/FBgn0028001 gene - - - "1197/15, l(3)S119715" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004408 tnk tonock http://flybase.org/reports/FBgn0004408 - gene - - - tnk - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085257 CG34228 - http://flybase.org/reports/FBgn0085257 protein_coding_gene - - - "CG34228, HDC05827" IPR031933:UPF0767 family CG34228 11-Aug-17 DroID_v2017_08 Drer\smim12 - - "Xtro\smim12, Xtro\LOC101734635" Mmus\Smim12 Hsap\SMIM12 FBgn0004844 l(3)88Bb lethal (3) 88Bb http://flybase.org/reports/FBgn0004844 - gene - - - "l(3)Z4, l(3)88Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0040964 CG18661 - http://flybase.org/reports/FBgn0040964 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD17344, CG18661" "IPR010342:Protein of unknown function DUF938, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG18661 11-Aug-17 DroID_v2017_08 "Drer\zgc:56719, Drer\zgc:103625" - Cele\Y26E6A.3 Xtro\c16orf13 Mmus\Mettl26 Hsap\METTL26 "viable,fertile" FBgn0034462 CG15905 - http://flybase.org/reports/FBgn0034462 protein_coding_gene - - - CG15905 - CG15905 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0065856 l(2)SH0294 lethal (2) SH0294 http://flybase.net/reports/FBgn0065856.html gene l(2)SH2 0294 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0036549 CG10516 - http://flybase.org/reports/FBgn0036549 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10516 "IPR001870:B30.2/SPRY domain, IPR003877:SPRY domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG10516 11-Aug-17 DroID_v2017_08 "Drer\spsb3a, Drer\ndufab1b, Drer\spsb3b, Drer\ndufab1a, Drer\si:dkey-23n7.10" - "Cele\madd-2, Cele\Y56A3A.19" "Xtro\ndufab1, Xtro\spsb3" "Mmus\Spsb3, Mmus\Ndufab1" Hsap\SPSB3 "viable,fertile" FBgn0052341 CG32341 - http://flybase.org/reports/FBgn0052341 protein_coding_gene - - - "BcDNA:SD01284, CG32341" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028522 BG:DS03192.3 BG:DS03192.3 http://flybase.org/reports/FBgn0028522 gene - - - "DS03192.3, DS003192.3, BG:DS03192.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001273 irreD irregular optic chiasma D http://flybase.org/reports/FBgn0001273 - gene - - - irreD - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263340 CR43421 - http://flybase.org/reports/FBgn0263340 non_protein_coding_gene - - - CR43421 - CR43421 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054028 CG34028 - http://flybase.org/reports/FBgn0054028 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1074, CG34028" IPR010512:Protein of unknown function DUF1091 CG34028 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054045 CG34045 - http://flybase.org/reports/FBgn0054045 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN001048184 "BP1009, CG34045" - CG34045 11-Aug-17 DroID_v2017_08 - - "Cele\C24D10.49, Cele\D1081.6, Cele\ZK757.10" - "Mmus\Ly6d, Mmus\2010109I03Rik" Hsap\LY6D FBgn0030375 CG11356 - http://flybase.org/reports/FBgn0030375 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006689 - - "CG11356, Arl13b" "IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG11356 11-Aug-17 DroID_v2017_08 "Drer\arl3l1, Drer\trim23, Drer\zgc:110197, Drer\arl2, Drer\arl13a, Drer\arl3l2, Drer\arl3" Scer\CIN4 "Cele\arc-1, Cele\arl-13, Cele\arl-3" "Xtro\arl3.1, Xtro\arl13a, Xtro\arl2, Xtro\arl3.2" "Mmus\Arl3, Mmus\Arl13a, Mmus\Arl2, Mmus\Trim23" "Hsap\ARL13A, Hsap\ARL3, Hsap\ARL2, Hsap\TRIM23" viable FBgn0266380 CR45022 - http://flybase.org/reports/FBgn0266380 non_protein_coding_gene - - - CR45022 - CR45022 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030696 CG8509 - http://flybase.org/reports/FBgn0030696 protein_coding_gene protein tyrosine phosphatase activator activity ; GO:0008160 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 mitotic spindle organization in nucleus ; GO:0030472 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 protein phosphatase type 2A complex ; GO:0000159 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 CG8509 "IPR004327:Phosphotyrosyl phosphatase activator, PTPA" CG8509 11-Aug-17 DroID_v2017_08 Drer\ppp2r4 "Scer\RRD2, Scer\RRD1" Cele\Y71H2AM.20 Xtro\ppp2r4 Mmus\Ptpa Hsap\PTPA viable DRSC20109 E -0.608331785 0.291037045 -1.814245608 -0.848802594 0.347951259 0.167287887 FBgn0085608 CG41312 - http://flybase.org/reports/FBgn0085608 protein_coding_gene - - - CG41312 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050381 PIG-X Phosphatidylinositol glycan anchor biosynthesis class X http://flybase.org/reports/FBgn0050381 protein_coding_gene molecular_function ; GO:0003674 | no biological data available GPI anchor biosynthetic process ; GO:0006506 | inferred from electronic annotation with InterPro:IPR013233 biological_process ; GO:0008150 | no biological data available endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR013233 cellular_component ; GO:0005575 | no biological data available "CG30381, PIG-X" "IPR013233:Glycosylphosphatidylinositol-mannosyltransferase I, PIG-X/PBN1" CG30381 11-Aug-17 DroID_v2017_08 Drer\pigx Scer\PBN1 Cele\F49E7.2 - Mmus\Pigx Hsap\PIGX viable FBgn0038915 CG17819 - http://flybase.org/reports/FBgn0038915 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006689, InterPro:IPR024156" small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR024156 "BcDNA:LP07781, CG17819" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024156:Small GTPase superfamily, ARF type" CG17819 11-Aug-17 DroID_v2017_08 "Drer\arl5a, Drer\arl4ab, Drer\zgc:110197, Drer\arl5c, Drer\arl13a, Drer\zgc:110286, Drer\arf4a, Drer\arl4ca, Drer\arl11, Drer\arl4d, Drer\arl6, Drer\arl3, Drer\arl8, Drer\si:ch1073-165f9.2, Drer\arf2a, Drer\arl13b, Drer\arl3l2, Drer\arl4aa, Drer\arf5, Drer\zgc:77650, Drer\arl14, Drer\arl9, Drer\arl3l1, Drer\trim23, Drer\arf1, Drer\arf3a, Drer\arl4cb, Drer\arf3b" "Scer\ARL3, Scer\ARF2, Scer\ARF1" "Cele\arl-3, Cele\arl-13, Cele\arl-6" "Xtro\arl5b, Xtro\arl4a, Xtro\arf1, Xtro\arf4, Xtro\arl14, Xtro\arl3.1, Xtro\arf5, Xtro\arl13a, Xtro\arl9, Xtro\arl4c, Xtro\arl3.2, Xtro\arl11, Xtro\arf3, Xtro\trim23, Xtro\arl5c, Xtro\arl11, Xtro\arl6, Xtro\arl5a" "Mmus\Arl5b, Mmus\Arl13a, Mmus\Arl4d, Mmus\Arf5, Mmus\Trim23, Mmus\Arl3, Mmus\Arl5a, Mmus\Arf1, Mmus\Arf2, Mmus\Arl9, Mmus\Arf4, Mmus\Arl6, Mmus\Arl5c, Mmus\Arl4a, Mmus\Arf3, Mmus\Arl11, Mmus\Arl13b, Mmus\Arl4c" "Hsap\ARL13A, Hsap\ARL11, Hsap\ARL5C, Hsap\ARL5B, Hsap\ARL13B, Hsap\ARL17B, Hsap\ARF4, Hsap\ARL5A, Hsap\ARF5, Hsap\TRIM23, Hsap\ARL3, Hsap\ARL9, Hsap\ARL4D, Hsap\ARL6, Hsap\ARL14, Hsap\ARF1, Hsap\ARF3, Hsap\ARL4C, Hsap\ARL4A" viable FBgn0017435 anon-28Cd anon-28Cd http://flybase.org/reports/FBgn0017435 - gene - - - anon-28Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085331 CG34302 - http://flybase.org/reports/FBgn0085331 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34302 - CG34302 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029701 CG12691 - http://flybase.org/reports/FBgn0029701 protein_coding_gene - - - CG12691 IPR031957:Domain of unknown function DUF4777 CG12691 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030854 CG8289 - http://flybase.org/reports/FBgn0030854 protein_coding_gene - - - "CG8289, CC4" "IPR000953:Chromo/chromo shadow domain, IPR023780:Chromo domain, IPR016197:Chromo domain-like" CG8289 11-Aug-17 DroID_v2017_08 "Drer\cbx3a, Drer\cbx3b, Drer\cbx1b, Drer\cbx5, Drer\cbx1a" - "Cele\hpl-1, Cele\hpl-2" "Xtro\cbx5, Xtro\cbx3, Xtro\cbx1" "Mmus\Cbx1, Mmus\Cbx5" "Hsap\CBX5, Hsap\CBX3, Hsap\CBX1" "viable,fertile" FBgn0266393 CR45033 - http://flybase.org/reports/FBgn0266393 pseudogene_attribute - - - "CR31541, CR45033" - CR45033 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259716 CG42370 - http://flybase.org/reports/FBgn0259716 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" cellular_component ; GO:0005575 | no biological data available "CG9511, CG9508, CG33295, CG13981, CT26920, CG42370" "IPR024079:Metallopeptidase, catalytic domain, IPR018497:Peptidase M13, C-terminal domain, IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain" CG42370 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\ece2b, Drer\mmel1, Drer\phex" - "Cele\nep-26, Cele\nep-7, Cele\nep-8, Cele\nep-3, Cele\nep-20, Cele\nep-21, Cele\nep-18, Cele\nep-6, Cele\nep-23, Cele\nep-13, Cele\nep-5, Cele\nep-9, Cele\nep-19, Cele\nep-12, Cele\nep-10, Cele\nep-24" "Xtro\ecel1, Xtro\mmel1, Xtro\ece1, Xtro\ece2" "Mmus\Mmel1, Mmus\Ece1, Mmus\Ece2, Mmus\Ecel1, Mmus\Mme, Mmus\Phex, Mmus\Kel" "Hsap\KEL, Hsap\MME, Hsap\ECE2, Hsap\ECE1, Hsap\MMEL1, Hsap\PHEX, Hsap\ECEL1" viable FBgn0003542 stt spotty http://flybase.org/reports/FBgn0003542 - gene - - - stt - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,reduced,male sterile,visible,body color defective" "wing,adult abdomen,microchaeta,eye,macrochaeta,tergite" FBgn0016677 Mab13D2 Monoclonal antibody 13D2 http://flybase.org/reports/FBgn0016677 - gene - - - Mab13D2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001321 knk knickkopf http://flybase.org/reports/FBgn0001321 "FBgn0037790, FBgn0042639" protein_coding_gene - "chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype cuticle chitin biosynthetic process ; GO:0006035 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor regulation of tube architecture, open tracheal system ; GO:0035152 | inferred from mutant phenotype regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype chitin biosynthetic process ; GO:0006031 | inferred from mutant phenotype embryonic epithelial tube formation ; GO:0001838 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from genetic interaction with tor" - "CG6217, gnar, l(3)85Eg, knk, Knk, Gnarled, dyspneic" "IPR005018:DOMON domain, IPR019545:DM13 domain" CG6217 11-Aug-17 DroID_v2017_08 - - "Cele\H06A10.1, Cele\W01C8.5" - Mmus\Thbd Hsap\THBD "lethal,visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval dorsal trunk,embryonic/larval transverse connective,embryonic/larval tracheal system,tracheal system,denticle belt,cephalopharyngeal skeleton,wing hair,somatic clone,epicuticle,procuticle,presumptive embryonic/larval tracheal system,embryonic/larval cuticle,larval head,vertical bridge,embryonic/first instar larval cuticle,terminal tracheal cell,eye" FBgn0027209 l(1)G0363 lethal (1) G0363 http://flybase.org/reports/FBgn0027209 - gene - - - l(1)G0363 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,viable" FBgn0266811 CR45273 - http://flybase.org/reports/FBgn0266811 non_protein_coding_gene - - - CR45273 - CR45273 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003338 scruff scruff http://flybase.org/reports/FBgn0003338 - gene - - - "scr, scruff" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "macrochaeta,microchaeta,wing,scutellum" FBgn0036859 CG14085 - http://flybase.org/reports/FBgn0036859 protein_coding_gene - - - CG14085 IPR027993:Protein of unknown function DUF4495 CG14085 11-Aug-17 DroID_v2017_08 Drer\si:ch73-280o22.2 - "Cele\C36C5.5, Cele\T28A11.3, Cele\W10G11.2, Cele\C36C5.14, Cele\C36C5.4, Cele\fbxa-111, Cele\W10G11.3, Cele\pud-2.2, Cele\T13F3.4, Cele\C04E12.2, Cele\pud-2.1, Cele\ZK105.1, Cele\T20D4.11, Cele\C17B7.3, Cele\C36C5.12" - Mmus\2210408I21Rik Hsap\KIAA0825 viable FBgn0028294 l(1)G0392 lethal (1) G0392 http://flybase.org/reports/FBgn0028294 gene - - - l(1)G0392 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061094 l(3)S010917b lethal (3) S010917b http://flybase.org/reports/FBgn0061094 gene - - - "0109/17, l(3)S010917b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028019 l(3)S104115 lethal (3) S104115 http://flybase.org/reports/FBgn0028019 gene - - - l(3)S104115 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259676 DNApol-alpha60 DNA polymerase alpha 60kD http://flybase.org/reports/FBgn0259676 protein_coding_gene DNA primase activity ; GO:0003896 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000830013 DNA primase activity ; GO:0003896 | inferred from sequence or structural similarity DNA-directed DNA polymerase activity ; GO:0003887 | traceable author statement single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000830013 "DNA replication, synthesis of RNA primer ; GO:0006269 | inferred from electronic annotation with InterPro:IPR007238 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from direct assay DNA-dependent DNA replication ; GO:0006261 | traceable author statement DNA replication ; GO:0006260 | inferred from mutant phenotype" alpha DNA polymerase:primase complex ; GO:0005658 | traceable author statement alpha DNA polymerase:primase complex ; GO:0005658 | inferred from direct assay "Dmpol alpha, pol alpha, DNA polalpha, DNApol-alpha60, Pol, DNAprimase, S(faf)240, l(3)j10B2, l(3)77ABe, CG5553, BcDNA:GM13640, DNAprim, GM13640, Polalpha 60 kDa, polalpha" "IPR007238:DNA primase large subunit, eukaryotic/archaeal, IPR016558:DNA primase, large subunit, eukaryotic" CG5553 11-Aug-17 DroID_v2017_08 Drer\prim2 Scer\PRI2 Cele\pri-2 Xtro\prim2 Mmus\Prim2 Hsap\PRIM2 DRSC11610 I 1.847159061 -1.133336803 0.47019141 -0.214543402 -0.099671186 0.284626687 FBgn0014040 Su(tor)1-163 Su(tor)1-163 http://flybase.org/reports/FBgn0014040 - gene - - - Su(tor)1-163 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0262515 VhaAC45 Vacuolar H[+] ATPase AC45 accessory subunit http://flybase.org/reports/FBgn0262515 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR008388 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | inferred from electronic annotation with InterPro:IPR008388 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008388 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 "proton-transporting V-type ATPase, V1 domain ; GO:0033180 | inferred from electronic annotation with InterPro:IPR008388 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype" "VhaAC45, vhaAC45, CG8029, anon-WO0118547.117, l(2)SH1634, l(2)SH2 1634" "IPR008388:ATPase, V1 complex, subunit S1" CG8029 11-Aug-17 DroID_v2017_08 "Drer\atp6ap1la, Drer\atp6ap1a, Drer\atp6ap1b, Drer\atp6ap1lb" - Cele\vha-19 Xtro\atp6ap1.2 "Mmus\Atp6ap1, Mmus\Atp6ap1l" "Hsap\ATP6AP1, Hsap\ATP6AP1L" "lethal,recessive" FBgn0010387 Dbi Diazepam-binding inhibitor http://flybase.org/reports/FBgn0010387 "FBgn0046463, FBgn0047016" protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 fatty-acyl-CoA binding ; GO:0000062 | inferred from sequence or structural similarity cellular acyl-CoA homeostasis ; GO:0042049 | inferred from sequence or structural similarity - "ACBP, DBI, CG8627, BcDNA:RH39533, anon-WO0172774.131, Dbi, dbi" "IPR000582:Acyl-CoA-binding protein, ACBP, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR022408:Acyl-CoA-binding protein, ACBP, conserved site" CG8627 11-Aug-17 DroID_v2017_08 "Drer\dbi, Drer\acbd6, Drer\zgc:92030, Drer\acbd7, Drer\acbd5b, Drer\acbd4, Drer\mettl23, Drer\LOC103909942" Scer\ACB1 "Cele\acbp-6, Cele\acbp-5, Cele\acbp-4, Cele\maa-1, Cele\acbp-3, Cele\acbp-1" "Xtro\acbd5, Xtro\acbd6, Xtro\eci2, Xtro\mettl23, Xtro\acbd7" "Mmus\Dbi, Mmus\Acbd7, Mmus\Eci2, Mmus\Acbd4, Mmus\Mettl23, Mmus\Acbd5, Mmus\Dbil5, Mmus\Acbd6" "Hsap\DBI, Hsap\ACBD6, Hsap\METTL23, Hsap\ACBD7, Hsap\ACBD5, Hsap\ACBD4, Hsap\ECI2" viable DRSC24352 K -0.367557499 0.742422986 -0.36955077 -0.053065981 0.614965637 1.748198619 FBgn0053438 5SrRNA:CR33438 5SrRNA:CR33438 http://flybase.org/reports/FBgn0053438 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33438, 5SrRNA:CR33438" - CR33438 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003579 Su(SD)X Suppressor of SD on the X http://flybase.org/reports/FBgn0003579 - gene - - - "supp-X(SD), su(SD), Su(SD), Su(SD)X" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263868 CR43715 - http://flybase.org/reports/FBgn0263868 non_protein_coding_gene - - - "CR43715, lincRNA.47" - CR43715 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054002 CG34002 - http://flybase.org/reports/FBgn0054002 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "BP1025, CG34002, MIP08535" "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG34002 11-Aug-17 DroID_v2017_08 "Drer\crispld1a, Drer\pi15b, Drer\glipr2l, Drer\LOC100536500, Drer\pi15a, Drer\glipr1b, Drer\glipr2, Drer\crispld1b, Drer\LOC101883528, Drer\r3hdml, Drer\crispld2" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\scl-25, Cele\scl-26, Cele\scl-23, Cele\scl-27, Cele\scl-24" "Xtro\crisp2, Xtro\crispld2, Xtro\crisp1, Xtro\crisp3, Xtro\MGC108118, Xtro\pi15, Xtro\r3hdml, Xtro\glipr2" "Mmus\Crisp1, Mmus\Crisp3, Mmus\Crispld1, Mmus\Crisp2, Mmus\Pi15, Mmus\R3hdml, Mmus\Clec18a, Mmus\Glipr1l1, Mmus\Crispld2, Mmus\Glipr2, Mmus\Crisp4, Mmus\Glipr1, Mmus\Glipr1l2, Mmus\Pi16" "Hsap\R3HDML, Hsap\PI16, Hsap\GLIPR1, Hsap\PI15, Hsap\CLEC18B, Hsap\CRISP3, Hsap\GLIPR1L1, Hsap\CRISPLD1, Hsap\CRISPLD2, Hsap\GLIPR2, Hsap\CLEC18C, Hsap\GLIPR1L2, Hsap\CRISP1, Hsap\CRISP2, Hsap\CLEC18A" DRSC26854 K -0.218804284 0.644771968 0.094639444 -0.529151718 -0.130708552 -1.507416894 FBgn0001312 kl-1 male fertility factor kl1 http://flybase.org/reports/FBgn0001312 - gene - - - "kl-1, Lms1" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0038217 CG14840 - http://flybase.org/reports/FBgn0038217 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG14840 IPR007999:Protein of unknown function DUF745 CG14840 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0052503 CG32503 - http://flybase.org/reports/FBgn0052503 protein_coding_gene - - - CG32503 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030878 CG6769 - http://flybase.org/reports/FBgn0030878 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003604 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000323791 "cytosolic large ribosomal subunit ; GO:0022625 | inferred from biological aspect of ancestor with PANTHER:PTN000323791 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000323791" CG6769 "IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013087:Zinc finger C2H2-type, IPR022755:Zinc finger, double-stranded RNA binding" CG6769 11-Aug-17 DroID_v2017_08 Drer\znf622 "Scer\REH1, Scer\REI1" Cele\C16A3.4 Xtro\znf622 Mmus\Zfp622 Hsap\ZNF622 "lethal,recessive" FBgn0038295 Gyc88E Guanylyl cyclase at 88E http://flybase.org/reports/FBgn0038295 protein_coding_gene nitric oxide binding ; GO:0070026 | inferred from direct assay heme binding ; GO:0020037 | inferred from direct assay oxygen sensor activity ; GO:0019826 | inferred from direct assay carbon monoxide binding ; GO:0070025 | inferred from direct assay guanylate cyclase activity ; GO:0004383 | inferred from direct assay guanylate cyclase activity ; GO:0004383 | non-traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:Q9VEU5 inferred from physical interaction with UniProtKB:Q9VEU6 oxygen binding ; GO:0019825 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:Q9VEU5 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Gyc88E "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 cGMP biosynthetic process ; GO:0006182 | inferred from direct assay response to reactive oxygen species ; GO:0000302 | inferred from direct assay cGMP biosynthetic process ; GO:0006182 | inferred by curator from GO:0004383 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 response to hypoxia ; GO:0001666 | inferred from mutant phenotype" "guanylate cyclase complex, soluble ; GO:0008074 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from direct assay guanylate cyclase complex, soluble ; GO:0008074 | inferred by curator from GO:0004383" "Gyc-88E, CG4154, GYC, Gyc88E" "IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR011644:Heme-NO binding, IPR024096:NO signalling/Golgi transport ligand-binding domain, IPR029787:Nucleotide cyclase, IPR011645:Haem NO binding associated" CG4154 11-Aug-17 DroID_v2017_08 "Drer\gucy1b2, Drer\gucy1b3, Drer\gucy1a3, Drer\gucy1a2" - "Cele\gcy-35, Cele\gcy-37, Cele\gcy-33, Cele\gcy-32, Cele\gcy-31, Cele\gcy-34, Cele\gcy-36" "Xtro\gucy1a2, Xtro\gucy1b3" "Mmus\Gucy1a3, Mmus\Gucy1a2, Mmus\Gucy1b3, Mmus\Gucy1b2" "Hsap\GUCY1A2, Hsap\GUCY1B3, Hsap\GUCY1A3" "stress response defective,viable,taste perception defective" FBgn0266415 CR45055 - http://flybase.org/reports/FBgn0266415 non_protein_coding_gene - - - CR45055 - CR45055 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028247 l(3)M256 lethal (3) M256 http://flybase.org/reports/FBgn0028247 gene - - - l(3)M256 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0064185 f::nec f::nec http://flybase.org/reports/FBgn0064185 engineered_fusion_gene - - - f::nec - - 11-Aug-17 DroID_v2017_08 - - - - - - melanotic necrosis "wing hair,chaeta" FBgn0053413 5SrRNA:CR33413 5SrRNA:CR33413 http://flybase.org/reports/FBgn0053413 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33413, 5SrRNA:CR33413" - CR33413 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052017 CG32017 - http://flybase.org/reports/FBgn0052017 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32017 - CG32017 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039612 CG14523 - http://flybase.org/reports/FBgn0039612 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG14523 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG14523 11-Aug-17 DroID_v2017_08 "Drer\ece2b, Drer\ece1, Drer\phex, Drer\mmel1" - "Cele\nep-19, Cele\nep-2, Cele\nep-7, Cele\nep-3, Cele\nep-16, Cele\nep-9, Cele\nep-20, Cele\nep-1, Cele\nep-8, Cele\nep-24, Cele\nep-17, Cele\nep-13, Cele\nep-10, Cele\nep-12, Cele\nep-26, Cele\nep-11, Cele\nep-5, Cele\nep-6, Cele\nep-21, Cele\nep-23, Cele\nep-18" "Xtro\mmel1, Xtro\ece1, Xtro\ecel1, Xtro\ece2" "Mmus\Ece2, Mmus\Ecel1, Mmus\Ece1, Mmus\Mme, Mmus\Phex, Mmus\Kel, Mmus\Mmel1" "Hsap\ECE1, Hsap\ECE2, Hsap\MMEL1, Hsap\ECEL1, Hsap\MME, Hsap\KEL, Hsap\PHEX" "viable,visible" trichogen cell FBgn0040600 CG13631 - http://flybase.org/reports/FBgn0040600 protein_coding_gene - - - "CG13631, BcDNA:GH19356" - CG13631 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034461 CG15124 - http://flybase.org/reports/FBgn0034461 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15124 - CG15124 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053535 tRNA:Glu-TTC-1-3 transfer RNA:Glutamic acid-TTC 1-3 http://flybase.org/reports/FBgn0053535 tRNA_gene GAA codon-amino acid adaptor activity ; GO:0033459 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033459 cytosol ; GO:0005829 | inferred by curator from GO:0033459 "AE002787.trna8-GluTTC, tRNA:E:TTC:AE002787-d, CR33535, chr2R.trna66-GluTTC, tRNA:Glu-TTC-1-3, tRNA:CR33535, tRNA-Glu-TTC-1-3, GAA" - CR33535 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040893 CG14774 - http://flybase.org/reports/FBgn0040893 protein_coding_gene - - - CG14774 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003613 Su(var)2-11 Suppressor of variegation 2-11 http://flybase.org/reports/FBgn0003613 - gene - - - "Su-var(2)11, Su(var)2-11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,suppressor of variegation,dominant" FBgn0037660 beag beag http://flybase.org/reports/FBgn0037660 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 terminal button organization ; GO:0072553 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "beag, CG18005" "IPR012492:Protein RED, C-terminal, IPR012916:RED-like, N-terminal" CG18005 11-Aug-17 DroID_v2017_08 "Drer\ik, Drer\wdr55" Scer\JIP5 "Cele\smu-2, Cele\Y44F5A.1" Xtro\ik "Mmus\Ik, Mmus\Wdr55" "Hsap\IK, Hsap\WDR55" "partially lethal - majority die,neuroanatomy defective,neurophysiology defective,viable,planar polarity defective" "NMJ bouton,germline cell,male" FBgn0031876 Atac1 Ada2a-containing complex component 1 http://flybase.org/reports/FBgn0031876 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay histone H4 acetylation ; GO:0043967 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay "Atac1, CG9200, dATAC1" "IPR001005:SANT/Myb domain, IPR009057:Homeobox domain-like" CG9200 11-Aug-17 DroID_v2017_08 Drer\zzz3 - - Xtro\zzz3 Mmus\Zzz3 Hsap\ZZZ3 viable FBgn0261397 didum dilute class unconventional myosin http://flybase.org/reports/FBgn0261397 protein_coding_gene "motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR008989 actin filament binding ; GO:0051015 | inferred from electronic annotation with InterPro:IPR008989 ATP binding ; GO:0005524 | inferred from direct assay ATP binding ; GO:0005524 | inferred from sequence or structural similarity with MGI:MGI:105976 actin-dependent ATPase activity ; GO:0030898 | inferred from direct assay calcium-dependent ATPase activity ; GO:0030899 | inferred from direct assay myosin light chain binding ; GO:0032027 | inferred from physical interaction with Mlc-c actin binding ; GO:0003779 | inferred from sequence or structural similarity with MGI:MGI:105976 calmodulin binding ; GO:0005516 | inferred from physical interaction with Cam myosin light chain binding ; GO:0032027 | inferred from physical interaction with Cam inferred from physical interaction with Mlc-c actin binding ; GO:0003779 | inferred from direct assay ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" "actin filament-based movement ; GO:0030048 | inferred from direct assay sperm individualization ; GO:0007291 | inferred from mutant phenotype positive regulation of pole plasm oskar mRNA localization ; GO:0045856 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype oogenesis ; GO:0048477 | NOT inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype inferred from genetic interaction with crb rhabdomere development ; GO:0042052 | inferred from mutant phenotype mitochondrion transport along microtubule ; GO:0047497 | inferred from direct assay" myosin complex ; GO:0016459 | inferred from sequence or structural similarity with MGI:MGI:105976 myosin V complex ; GO:0031475 | inferred from physical interaction with Cam neuronal cell body ; GO:0043025 | inferred from direct assay myosin V complex ; GO:0031475 | inferred from physical interaction with Mlc-c rhabdomere ; GO:0016028 | inferred from direct assay myosin complex ; GO:0016459 | inferred from sequence or structural similarity "didum, M5, Didum, MyoV, soy, DmV, MYOV, CG2146, 43CD, NMC7, MyoV43CD, NEST:bs14c05, myoV, Myo5, Myo1C, dmM5" "IPR008989:Myosin S1 fragment, N-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site, IPR001609:Myosin head, motor domain, IPR002710:Dilute domain" CG2146 11-Aug-17 DroID_v2017_08 "Drer\myh10, Drer\myo16, Drer\vmhc, Drer\LOC100331349, Drer\myo5c, Drer\smyhc2, Drer\LOC100537963, Drer\myh14, Drer\LOC100333206, Drer\myhz2, Drer\myha, Drer\smyhc3, Drer\si:dkey-110c1.10, Drer\myhz1.2, Drer\LOC100329813, Drer\myh7bb, Drer\myh7ba, Drer\ns:zf-e68, Drer\myh9b, Drer\myhz1.1, Drer\myo5ab, Drer\myo5aa, Drer\myh9a, Drer\LOC100333572, Drer\myh11a, Drer\myo18ab, Drer\myh6, Drer\smyhc1, Drer\myh11b, Drer\vmhcl, Drer\LOC100329748, Drer\myhc4, Drer\myo18aa, Drer\myo5b, Drer\myhb" "Scer\MYO2, Scer\MYO1, Scer\MYO4" "Cele\unc-54, Cele\myo-2, Cele\nmy-1, Cele\myo-3, Cele\nmy-2, Cele\myo-5, Cele\hum-9, Cele\myo-1, Cele\unc-15, Cele\myo-6, Cele\hum-2" "Xtro\myo18b, Xtro\myo5a, Xtro\myo5b, Xtro\myh2, Xtro\myh11, Xtro\myh8, Xtro\myh15, Xtro\myh13, Xtro\myh4, Xtro\myh6, Xtro\myh9" "Mmus\Myo5a, Mmus\Myh1, Mmus\Myh4, Mmus\Myo5b, Mmus\Myh7b, Mmus\Myo19, Mmus\Myh3, Mmus\Myh6, Mmus\Myh14, Mmus\Myo16, Mmus\Myh8, Mmus\Myo18a, Mmus\Myh2, Mmus\Myh7, Mmus\Myh13, Mmus\Myh10, Mmus\Myh11, Mmus\Myh9, Mmus\Myo5c, Mmus\Myh15, Mmus\Myo18b" "Hsap\MYH7B, Hsap\MYH7, Hsap\MYH10, Hsap\MYH1, Hsap\MYH9, Hsap\MYO5C, Hsap\MYH15, Hsap\MYH4, Hsap\MYH13, Hsap\MYH8, Hsap\MYH3, Hsap\MYO19, Hsap\MYO18B, Hsap\MYO5B, Hsap\MYO5A, Hsap\MYO18A, Hsap\MYH6, Hsap\MYH11, Hsap\MYH2, Hsap\MYH14, Hsap\MYO16" " embryonic stage | stage 1-6 , adult stage | female , adult stage && oogenesis stage | stage S6-8 , embryonic stage , adult stage | male , adult stage && oogenesis stage | stage >S9 , adult stage && oogenesis stage , embryonic stage | stage 16 , embryonic stage && adult stage " "

ubiquitous , ovary

, oocyte | anterior

, testis

, nurse cell

, oocyte

, embryonic/larval hindgut

" FBgn0262537 CG43091 - http://flybase.org/reports/FBgn0262537 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43091 - CG43091 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065712 l(2)SH0586 lethal (2) SH0586 http://flybase.org/reports/FBgn0065712 gene - - - "l(2)SH0586, l(2)SH2 0586" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032809 CG13078 - http://flybase.org/reports/FBgn0032809 protein_coding_gene - - - CG13078 IPR006593:Cytochrome b561/ferric reductase transmembrane CG13078 11-Aug-17 DroID_v2017_08 "Drer\cyb561d2, Drer\cyb561d1" - - Xtro\cyb561d2 "Mmus\Cyb561d1, Mmus\Cyb561d2" "Hsap\CYB561D1, Hsap\CYB561D2" viable FBgn0005658 Ets65A Ets at 65A http://flybase.org/reports/FBgn0005658 "FBgn0035681, FBgn0040840" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000218930" "cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000218930" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 "Ets, D-ets-3, ETS3, D-Ets-3, ets65A, Ets3, CG6882, CG13294, CG7018, Ets65A" "IPR000418:Ets domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG7018 11-Aug-17 DroID_v2017_08 "Drer\etv4, Drer\gabpa, Drer\spic, Drer\erf, Drer\erg, Drer\etv1, Drer\ets2, Drer\fli1a, Drer\fli1b, Drer\etv2, Drer\fev, Drer\etv5a, Drer\elk3, Drer\elk1, Drer\elk4, Drer\erfl3, Drer\etv5b, Drer\LOC100537796, Drer\erfl1" - "Cele\ets-5, Cele\elf-1, Cele\ast-1" "Xtro\elk4, Xtro\elk1, Xtro\fli1, Xtro\ets1, Xtro\elk3, Xtro\erg, Xtro\etv3, Xtro\ets2, Xtro\gabpa, Xtro\erf, Xtro\etv2, Xtro\etv1" "Mmus\Ets1, Mmus\Fli1, Mmus\Etv4, Mmus\Etv3, Mmus\Etv1, Mmus\Gabpa, Mmus\Erg, Mmus\Erf, Mmus\Etv2, Mmus\Spib, Mmus\Elk1, Mmus\Fev, Mmus\Elk4, Mmus\Elk3, Mmus\Etv5, Mmus\Ets2" "Hsap\ERF, Hsap\ETS2, Hsap\GABPA, Hsap\ELK4, Hsap\ETV4, Hsap\ETS1, Hsap\ETV3, Hsap\ETV1, Hsap\ELK1, Hsap\SPIC, Hsap\ETV3L, Hsap\FEV, Hsap\ETV2, Hsap\ETV5, Hsap\ELK3, Hsap\FLI1, Hsap\ERG" embryonic stage ventral nerve cord

viable FBgn0016699 R2-element\ORF R2-element element ORF http://flybase.org/reports/FBgn0016699 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "R2Dm ORF, R2-element\ORF, R2, RT" "IPR013087:Zinc finger C2H2-type, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain, IPR009882:Gypsy, IPR000477:Reverse transcriptase domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003382 sha shavenoid http://flybase.org/reports/FBgn0003382 "FBgn0025509, FBgn0033618" protein_coding_gene molecular_function ; GO:0003674 | no biological data available antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype epidermal cell differentiation ; GO:0009913 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype cell cortex ; GO:0005938 | inferred from direct assay "CG13209, koj, sha, lincRNA.286" - CG13209 11-Aug-17 DroID_v2017_08 - - Cele\F31C3.6 - - - "visible,flightless,viable,somatic clone,flight defective,heat sensitive,recessive,partially lethal - majority die" "arista,trichome,denticle belt,3rd posterior cell | dorsal & wing hair | supernumerary,mesothoracic tergum & trichome,adult abdomen & trichome,dorsal denticle,wing hair,somatic clone,denticle,dorsal hair,embryonic/larval cuticle,heat sensitive,3rd posterior cell | dorsal & wing hair,3rd posterior cell | dorsal & wing hair | somatic clone,1st posterior cell | ventral & wing hair" FBgn0250874 ttm50 tiny tim 50 http://flybase.org/reports/FBgn0250874 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from biological aspect of ancestor with PANTHER:PTN000258719 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrial membrane organization ; GO:0007006 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000258720 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000258720 "ttm50, CG2713, i90, i238, EG:95B7.3, Gp99, 17944223" "IPR004274:FCP1 homology domain, IPR027111:Mitochondrial import inner membrane translocase subunit Tim50, IPR023214:HAD-like domain" CG2713 11-Aug-17 DroID_v2017_08 Drer\timm50 Scer\TIM50 Cele\scpl-4 Xtro\timm50 Mmus\Timm50 Hsap\TIMM50 DRSC18587 E -0.090070767 -0.460557644 -1.69496571 0.018321583 -0.496976442 -0.132459427 FBgn0069170 mcl(3)Z0684 mcl(3)Z0684 http://flybase.org/reports/FBgn0069170 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z0684 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0021982 l(2)k09903 lethal (2) k09903 http://flybase.org/reports/FBgn0021982 - gene - - - l(2)k09903 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060587 l(3)S093806b lethal (3) S093806b http://flybase.org/reports/FBgn0060587 gene - - - "0938/06, l(3)S093806b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002421 l(3)F12 lethal (3) F12 http://flybase.org/reports/FBgn0002421 - gene - - - "l(3)12, l(3)F12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" wing FBgn0027352 anon-93Ba anon-93Ba http://flybase.org/reports/FBgn0027352 - gene - - - anon-93Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022370 Pt-37 Adult protein-37 http://flybase.org/reports/FBgn0022370 - gene - - - Pt-37 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031689 Cyp28d1 Cyp28d1 http://flybase.org/reports/FBgn0031689 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CG10833, 28d1, Cyp28d1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10833 11-Aug-17 DroID_v2017_08 "Drer\cyp3c1, Drer\cyp3c4, Drer\cyp3c3, Drer\cyp3a65, Drer\tbxas1, Drer\cyp3c2" "Scer\ERG11, Scer\DIT2" "Cele\cyp-13A10, Cele\cyp-34A5, Cele\cyp-13B1, Cele\cyp-34A7, Cele\cyp-44A1, Cele\cyp-13A4, Cele\cyp-25A3, Cele\cyp-13A3, Cele\cyp-13A2, Cele\cyp-25A6, Cele\cyp-25A4, Cele\cyp-43A1, Cele\cyp-13A11, Cele\cyp-13A8, Cele\cyp-13A5, Cele\cyp-13B2, Cele\cyp-25A1, Cele\cyp-34A8, Cele\cyp-13A12, Cele\cyp-13A6, Cele\cyp-13A1, Cele\cyp-13A7, Cele\cyp-25A2" "Xtro\tbxas1, Xtro\cyp3a5, Xtro\cyp3a4, Xtro\LOC100494419" "Mmus\Cyp3a59, Mmus\Cyp3a57, Mmus\Cyp3a41b, Mmus\Cyp7b1, Mmus\Cyp3a11, Mmus\Cyp3a13, Mmus\Cyp3a41a, Mmus\Cyp3a25, Mmus\Tbxas1, Mmus\Cyp3a44, Mmus\Cyp3a16" "Hsap\CYP3A43, Hsap\CYP3A5, Hsap\CYP7B1, Hsap\CYP3A7-CYP3A51P, Hsap\TBXAS1, Hsap\CYP3A7, Hsap\CYP3A4" viable FBgn0265702 CR44509 - http://flybase.org/reports/FBgn0265702 non_protein_coding_gene - - - CR44509 - CR44509 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263864 Dark Death-associated APAF1-related killer http://flybase.org/reports/FBgn0263864 protein_coding_gene ADP binding ; GO:0043531 | inferred from electronic annotation with InterPro:IPR002182 CARD domain binding ; GO:0050700 | inferred from sequence model cysteine-type endopeptidase activator activity involved in apoptotic process ; GO:0008656 | inferred from biological aspect of ancestor with PANTHER:PTN001108738 ATP binding ; GO:0005524 | inferred from direct assay cysteine-type endopeptidase activity involved in apoptotic signaling pathway ; GO:0097199 | contributes_to inferred from direct assay cysteine-type endopeptidase activator activity involved in apoptotic process ; GO:0008656 | inferred from sequence or structural similarity with HGNC:576 activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from sequence or structural similarity with HGNC:576 apoptotic process ; GO:0006915 | traceable author statement protein homooligomerization ; GO:0051260 | inferred from direct assay melanization defense response ; GO:0035006 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype central nervous system formation ; GO:0021556 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from genetic interaction with hid activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | traceable author statement regulation of retinal cell programmed cell death ; GO:0046668 | non-traceable author statement negative regulation of humoral immune response ; GO:0002921 | inferred from mutant phenotype positive regulation of glial cell apoptotic process ; GO:0034352 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c ; GO:0008635 | traceable author statement response to starvation ; GO:0042594 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with Ank2 positive regulation of compound eye retinal cell programmed cell death ; GO:0046672 | inferred from mutant phenotype salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype S-adenosylmethionine cycle ; GO:0033353 | inferred from mutant phenotype sarcosine catabolic process ; GO:1901053 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from sequence or structural similarity with HGNC:576 inferred from physical interaction with Dredd programmed cell death ; GO:0012501 | non-traceable author statement protein heterooligomerization ; GO:0051291 | inferred from direct assay sensory organ development ; GO:0007423 | inferred from mutant phenotype programmed cell death ; GO:0012501 | inferred from direct assay apoptotic process ; GO:0006915 | non-traceable author statement response to gamma radiation ; GO:0010332 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c ; GO:0008635 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype apoptosome ; GO:0043293 | inferred from direct assay "ark, Ark, Dark, dark, dApaf1, Hac1, l(2)SH0173, CG6829, Apaf-1, Dapaf-1, Dapaf-1/HAC-1, hac-1, Dark/Dapaf-1/HAC1, dapaf, D-Apaf-1, dapaf-1, ARK, dark/hac-1/dapaf-1, Dark/Hac-1/dApaf-1, dArk, DARK, dApaf-1, Hac-1, arc, dApaf-1/DARK/HAC-1, dark/dapaf-1/hac-1, Hac-1/Dark, dapaf-1S, dapaf-1L, T1, anon-53Fa, Dark/Apaf-I, apaf-1, Apaf1, apaf1, hac1, dAPAF-1, Dark/Hac-1/dApaf1, APAF1, APAF-1, Apaf" "IPR017986:WD40-repeat-containing domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR015943:WD40/YVTN repeat-like-containing domain, IPR002182:NB-ARC, IPR001680:WD40 repeat" CG6829 11-Aug-17 DroID_v2017_08 Drer\apaf1 - Cele\ced-4 Xtro\apaf1 Mmus\Apaf1 Hsap\APAF1 " embryonic stage | stage 7 , embryonic stage | stage 10-11 , embryonic stage , larval stage | third instar , embryonic stage -- adult stage , embryonic stage&&larval stage&&pupal stage , embryonic stage | early " " anterior transverse furrow && cephalic furrow && posterior transverse furrow && ventral furrow

, procephalic neurogenic region

, eye disc

,

ubiquitous , head mesoderm

, ventral neurogenic region

, dorsal mesothoracic disc

" FBgn0264819 CR44027 - http://flybase.org/reports/FBgn0264819 non_protein_coding_gene - - - CR44027 - CR44027 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003332 sch slender chaetae http://flybase.org/reports/FBgn0003332 - gene - - - sch - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile,eye color defective" "pigment cell,macrochaeta,eye" FBgn0025111 Ant2 Adenine nucleotide translocase 2 http://flybase.org/reports/FBgn0025111 "FBgn0027300, FBgn0028338, FBgn0040166, FBgn0064129" protein_coding_gene ATP:ADP antiporter activity ; GO:0005471 | inferred from biological aspect of ancestor with PANTHER:PTN000640049 ATP:ADP antiporter activity ; GO:0005471 | inferred from sequence or structural similarity with UniProtKB:P12235 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067, InterPro:IPR002113 ADP transport ; GO:0015866 | inferred from sequence or structural similarity with UniProtKB:P12235 regulation of mitochondrial membrane permeability ; GO:0046902 | inferred from biological aspect of ancestor with PANTHER:PTN000640049 ATP transport ; GO:0015867 | inferred from sequence or structural similarity with UniProtKB:P12235" integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:P12235 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640050 lipid particle ; GO:0005811 | inferred from direct assay "l(1)G0126, l(1)G0247, l(1)G0386, CG1683, Ant2, ANT2" "IPR002067:Mitochondrial carrier protein, IPR002113:Adenine nucleotide translocator 1, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG1683 11-Aug-17 DroID_v2017_08 "Drer\slc25a5, Drer\slc25a6, Drer\si:dkey-251i10.1, Drer\parvaa, Drer\parvab, Drer\slc25a4" "Scer\PET9, Scer\AAC1, Scer\AAC3" "Cele\ant-1.1, Cele\R07E3.4, Cele\F25B4.7, Cele\ant-1.2, Cele\C47E12.2, Cele\ant-1.3, Cele\pat-6, Cele\ant-1.4" "Xtro\slc25a4, Xtro\slc25a5, Xtro\parvb" "Mmus\Slc25a5, Mmus\Slc25a31, Mmus\Parva, Mmus\Parvb, Mmus\Slc25a4" "Hsap\SLC25A31, Hsap\PARVB, Hsap\SLC25A6, Hsap\SLC25A5, Hsap\PARVA, Hsap\SLC25A4" adult stage "viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of P-stage,some die during pharate adult stage,some die during pupal stage" DRSC19330 E -0.14910592 -0.718609089 -2.38946575 -0.372629741 -0.741777163 0.286176349 FBgn0000729 fs(1)5e female sterile (1) 5e http://flybase.org/reports/FBgn0000729 - gene - - - fs(1)5e - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,heat sensitive,male fertile" FBgn0025144 ms(3)A3 ms(3)A3 http://flybase.org/reports/FBgn0025144 - gene - - - ms(3)A3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0016959 tilP touch insensitive larva P http://flybase.org/reports/FBgn0016959 - gene - - - "line 78, tilP" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0265934 CR44723 - http://flybase.org/reports/FBgn0265934 non_protein_coding_gene - - - "CR44723, lincRNA.509" - CR44723 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083232 EP718 EP718 http://flybase.org/reports/FBgn0083232 gene - - - EP718 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062541 Juan\pol Juan element pol http://flybase.org/reports/FBgn0062541 transposable_element_gene - - - "Strider\pol, Juan\pol, pol" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026245 fph fast phase http://flybase.org/reports/FBgn0026245 - gene - - - fph - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066074 Su(rux)2C Su(rux)2C http://flybase.org/reports/FBgn0066074 gene - second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | non-traceable author statement - Su(rux)2C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000051 ade1 adenosine 1 http://flybase.org/reports/FBgn0000051 - gene - - - "ade1-1[sd], ade1-1, ade1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "auxotroph,recessive" FBgn0040859 CR32658 - http://flybase.org/reports/FBgn0040859 non_protein_coding_gene - - - "CG11358, CR32658" - CR32658 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001722 l(1)ESHS43 lethal (1) ESHS43 http://flybase.org/reports/FBgn0001722 - gene - - - l(1)ESHS43 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033850 CG13331 - http://flybase.org/reports/FBgn0033850 protein_coding_gene - - - CG13331 - CG13331 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0070038 3R-64-33 3R-64-33 http://flybase.org/reports/FBgn0070038 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-64-33 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" FBgn0262220 mir-987 mir-987 stem loop http://flybase.org/reports/FBgn0262220 miRNA_gene - muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-987, miR-987, mir-987, CR42927, dme-miR-987" - CR42927 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "wing,wing vein" FBgn0051848 CG31848 - http://flybase.org/reports/FBgn0051848 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31848 IPR031732:Protein of unknown function DUF4729 CG31848 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040726 dpr1 defective proboscis extension response 1 http://flybase.org/reports/FBgn0040726 protein_coding_gene molecular_function ; GO:0003674 | no biological data available salt aversion ; GO:0035199 | inferred from mutant phenotype sensory perception of salty taste ; GO:0050914 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG13439, Dpr-1, DPR1, dpr1, dpr, Dpr1" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG13439 11-Aug-17 DroID_v2017_08 "Drer\LOC100333196, Drer\LOC101885725, Drer\si:ch211-264f5.6, Drer\LOC101885444, Drer\si:dkey-65b12.12, Drer\si:ch211-163c2.2" - Cele\zig-8 "Xtro\obsl1, Xtro\nfasc" Mmus\Amica1 - "taste perception defective,recessive,viable" FBgn0267441 CR45791 - http://flybase.org/reports/FBgn0267441 non_protein_coding_gene - - - CR45791 - CR45791 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044086 E(rst)F84 E(rst)F84 http://flybase.org/reports/FBgn0044086 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "F84, E(rst)F84" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0066363 ikar ikar http://flybase.org/reports/FBgn0066363 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ikar - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,memory defective,chemical sensitive" FBgn0036985 zye zye http://flybase.org/reports/FBgn0036985 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with dy apical constriction ; GO:0003383 | inferred from mutant phenotype cell-matrix adhesion ; GO:0007160 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay "zye, CG5847" IPR001507:Zona pellucida domain CG5847 11-Aug-17 DroID_v2017_08 - - "Cele\pqn-13, Cele\cutl-24, Cele\cutl-20, Cele\cutl-4, Cele\cutl-19, Cele\cutl-9, Cele\T01D1.8, Cele\F07H5.8, Cele\F35A5.4, Cele\cutl-7, Cele\cutl-10, Cele\cutl-12, Cele\cutl-29, Cele\cutl-2, Cele\cutl-8, Cele\F46G11.6, Cele\cut-5, Cele\cut-3, Cele\dpy-1, Cele\M02G9.1, Cele\cutl-3, Cele\cutl-16, Cele\cutl-14, Cele\cutl-28, Cele\cut-1, Cele\cutl-26, Cele\cutl-1, Cele\cut-4, Cele\cutl-13, Cele\cutl-15, Cele\cut-6, Cele\cutl-5, Cele\cutl-6, Cele\ram-5, Cele\cutl-22, Cele\cutl-25, Cele\cutl-11" - - Hsap\KRTAP16-1 viable denticle FBgn0020567 anon-88Ac anon-88Ac http://flybase.org/reports/FBgn0020567 - gene - - - anon-88Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000604 E(var)303 Enhancer of variegation 303 http://flybase.org/reports/FBgn0000604 - gene - - - "En(var)303, E(var)303" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,enhancer of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0267060 CR45504 - http://flybase.org/reports/FBgn0267060 non_protein_coding_gene - - - CR45504 - CR45504 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013276 Hsp70Ab Heat-shock-protein-70Ab http://flybase.org/reports/FBgn0013276 "FBgn0001231, FBgn0042100" protein_coding_gene - response to unfolded protein ; GO:0006986 | non-traceable author statement response to heat ; GO:0009408 | non-traceable author statement response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "Hsp70Ab, Hsp70, hsp70, HSP70, hsp 70, hsp70Ab, GRP78, hsp70A, Hsp70A, hsp-70, hsp70(87A), DMHSP7A2, Hsp 70, dhsp70, hs70, hsp70 87A, CG18743, Hsp-70, hsp70a, Hsp70b, dHsp70, Hsp70ab, Hsp70aB, Hsp70-Ab, Dm-hsp70, HSP70Ab" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG18743 11-Aug-17 DroID_v2017_08 "Drer\hspa13, Drer\hsc70, Drer\hspa12a, Drer\nckap1, Drer\hspa14, Drer\hspa5, Drer\hsp70.1, Drer\hsp70.2, Drer\si:ch211-199o1.2, Drer\si:dkey-4p15.3, Drer\hspa12b, Drer\hspa8, Drer\hsp70l" "Scer\SSA2, Scer\SSB2, Scer\SSA1, Scer\SSA4, Scer\SSB1, Scer\SSZ1, Scer\SSA3, Scer\SSQ1, Scer\KAR2" "Cele\hsp-70, Cele\hsp-4, Cele\hsp-3, Cele\gex-3, Cele\F44E5.5, Cele\F11F1.1, Cele\F44E5.4, Cele\hsp-1" "Xtro\hspa5, Xtro\hspa14, Xtro\hspa1b, Xtro\hspa12b, Xtro\hspa13, Xtro\hspa1l, Xtro\hspa2, Xtro\hspa8, Xtro\nckap1, Xtro\nckap1l, Xtro\hspa1a, Xtro\hsp70" "Mmus\Hspa8, Mmus\Nckap1, Mmus\Hspa12a, Mmus\Hspa1a, Mmus\Hspa5, Mmus\Hspa1l, Mmus\Hspa12b, Mmus\Hspa13, Mmus\Hspa14, Mmus\Hspa2, Mmus\Nckap1l, Mmus\Hspa1b" "Hsap\HSPA1B, Hsap\NCKAP1L, Hsap\HSPA8, Hsap\HSPA12A, Hsap\HSPA1A, Hsap\HSPA13, Hsap\HSPA2, Hsap\HSPA12B, Hsap\NCKAP1, Hsap\HSPA1L, Hsap\HSPA6, Hsap\HSPA5, Hsap\HSPA14" FBgn0082670 GS1061 GS1061 http://flybase.org/reports/FBgn0082670 gene - - - GS1061 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062943 CR32769 - http://flybase.org/reports/FBgn0062943 non_protein_coding_gene - - - "BcDNA:RH39175, CR32769" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030770 CG13010 - http://flybase.org/reports/FBgn0030770 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13010 - CG13010 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262419 mir-277 mir-277 stem loop http://flybase.org/reports/FBgn0262419 miRNA_gene - gene silencing by miRNA ; GO:0035195 | inferred from direct assay positive regulation of neuron death ; GO:1901216 | inferred from genetic interaction with Fmr1 - "dme-mir-277, mir-277, miR-277, Dme-miR-277, MIR-277, CR42968, miR277, CR33588, MiR-277, dme-miR-277-5p, dme-miR-277" - CR42968 11-Aug-17 DroID_v2017_08 - - - - - - "viable,short lived,visible,partially lethal - majority die,some die during pupal stage,lethal,gravitaxis defective,conditional,heat stress response defective,neuroanatomy defective" "wing,wing margin,adult brain,conditional,eye" FBgn0029833 MCTS1 Malignant T cell amplified sequence 1 http://flybase.org/reports/FBgn0029833 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002478, InterPro:IPR004521" formation of translation preinitiation complex ; GO:0001731 | inferred from biological aspect of ancestor with PANTHER:PTN000513830 translation reinitiation ; GO:0002188 | inferred from direct assay positive regulation of translational initiation ; GO:0045948 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from physical interaction with DENR cytosolic small ribosomal subunit ; GO:0022627 | inferred from biological aspect of ancestor with PANTHER:PTN000513830 "anon-WO03040301.151, anon-WO03040301.150, CG5941, MCTS1, MCT-1" "IPR015947:PUA-like domain, IPR002478:PUA domain, IPR004521:Uncharacterised domain CHP00451, IPR016437:MCT-1/Tma20" CG5941 11-Aug-17 DroID_v2017_08 Drer\mcts1 Scer\TMA20 Cele\C11D2.7 Xtro\mcts1 "Mmus\Mcts2, Mmus\Mcts1" Hsap\MCTS1 FBgn0001695 l(1)ESHS16 lethal (1) ESHS16 http://flybase.org/reports/FBgn0001695 - gene - - - l(1)ESHS16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040009 CG17490 - http://flybase.org/reports/FBgn0040009 protein_coding_gene - - - CG17490 - CG17490 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026605 Act88F::Hsap\ACTC1 Act88F::Hsap\ACTC http://flybase.org/reports/FBgn0026605 - engineered_fusion_gene - - - "Act88F::Hsap\ACTC, Act88F::Hsap\ACTC1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060698 l(3)S072114 lethal (3) S072114 http://flybase.org/reports/FBgn0060698 gene - - - "0721/14, l(3)S072114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0004693 Snb Snowblind http://flybase.org/reports/FBgn0004693 - gene - - - Snb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004166 l(2)52AD lethal (2) 52AD http://flybase.org/reports/FBgn0004166 - gene - - - l(2)52AD - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0266791 CR45256 - http://flybase.org/reports/FBgn0266791 non_protein_coding_gene - - - CR45256 - CR45256 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060729 l(3)S067501 lethal (3) S067501 http://flybase.org/reports/FBgn0060729 gene - - - "0675/01, l(3)S067501" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0020777 tak takahe http://flybase.org/reports/FBgn0020777 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "bee, tak" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "wing,somatic clone,embryonic/first instar larval cuticle,dorsal,presumptive embryonic/larval digestive system,myoblast,dorsal closure embryo" FBgn0033727 Or49a Odorant receptor 49a http://flybase.org/reports/FBgn0033727 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 olfactory receptor activity ; GO:0004984 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory behavior ; GO:0042048 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | non-traceable author statement "CG13158, 49a, DOR10, 49A.1, Or49a, OR49a" "IPR004117:Olfactory receptor, insect" CG13158 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,smell perception defective,visible" trichogen cell FBgn0082937 snoRNA:Me28S-C2645b - http://flybase.org/reports/FBgn0082937 snoRNA_gene - - - "CR34588, snoRNA:Me28S-C2645b, Me28S-Cm2645b, snoRNA:Me28S-Cm2645b, DmSnR64b" - CR34588 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070045 3R-168-17 3R-168-17 http://flybase.org/reports/FBgn0070045 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-168-17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic segment,germline clone,maternal effect,embryonic/first instar larval cuticle" FBgn0004485 l(1)air12 lethal aberrant immune response 12 http://flybase.org/reports/FBgn0004485 - gene - - - l(1)air12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass" FBgn0031547 Sr-CIV "Scavenger receptor class C, type IV" http://flybase.org/reports/FBgn0031547 protein_coding_gene polysaccharide binding ; GO:0030247 | inferred from electronic annotation with InterPro:IPR001212 scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001212 immune response ; GO:0006955 | inferred from electronic annotation with InterPro:IPR001212 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000998 "CG3212, CT10789, Sr-CIV, SR-CIV" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR000436:Sushi/SCR/CCP domain, IPR000998:MAM domain, IPR001212:Somatomedin B domain" CG3212 11-Aug-17 DroID_v2017_08 "Drer\mep1a.1, Drer\mep1a.2, Drer\malrd1, Drer\mep1b, Drer\si:ch73-40a17.3, Drer\mamdc1, Drer\wu:fb63a08" - - - "Mmus\Mdga1, Mmus\Mdga2, Mmus\Cd55b, Mmus\Malrd1, Mmus\Cd55, Mmus\Mamdc2" "Hsap\MDGA1, Hsap\MDGA2, Hsap\MAMDC2, Hsap\MALRD1" viable FBgn0264939 CR44108 - http://flybase.org/reports/FBgn0264939 non_protein_coding_gene - - - CR44108 - CR44108 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065825 l(2)SH0360 lethal (2) SH0360 http://flybase.org/reports/FBgn0065825 gene - - - "l(2)SH0360, l(2)SH2 0360" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265201 CG44261 - http://flybase.org/reports/FBgn0265201 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44261 - CG44261 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260357 GSd420 - http://flybase.org/reports/FBgn0260357 gene - - - GSd420 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve" FBgn0266624 CR45131 - http://flybase.org/reports/FBgn0266624 non_protein_coding_gene - - - CR45131 - CR45131 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004015 with with trident http://flybase.org/reports/FBgn0004015 - gene - - - with - - 11-Aug-17 DroID_v2017_08 - - - - - - scutum FBgn0026203 mkf mokkaife http://flybase.org/reports/FBgn0026203 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available mkf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029035 l(2)Q1 lethal (2) Q1 http://flybase.org/reports/FBgn0029035 gene - - - "Q1, l(2)Q1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039343 CG5111 - http://flybase.org/reports/FBgn0039343 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:17623 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:17623 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:17623 CG5111 "IPR015940:Ubiquitin-associated domain, IPR009060:UBA-like, IPR029071:Ubiquitin-related domain" CG5111 11-Aug-17 DroID_v2017_08 "Drer\nub1, Drer\zgc:153057" - - Xtro\nub1 Mmus\Nub1 Hsap\NUB1 viable FBgn0016025 l(3)89Bn lethal (3) 89Bn http://flybase.org/reports/FBgn0016025 - gene - - - l(3)89Bn - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027959 l(3)S147506 lethal (3) S147506 http://flybase.org/reports/FBgn0027959 gene - - - l(3)S147506 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023416 Ac3 Ac3 http://flybase.org/reports/FBgn0023416 - protein_coding_gene adenylate cyclase activity ; GO:0004016 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 adenylate cyclase activity ; GO:0004016 | inferred from direct assay "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 locomotor rhythm ; GO:0045475 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cAMP biosynthetic process ; GO:0006171 | inferred from direct assay cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 integral component of membrane ; GO:0016021 | non-traceable author statement" "CG1506, AC 3, DAC39E, DAC3, Ac3, AC3, ac3" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR030672:Adenylate cyclase, IPR029787:Nucleotide cyclase, IPR032628:Adenylate cyclase, N-terminal" CG1506 11-Aug-17 DroID_v2017_08 "Drer\ugt5a2, Drer\ugt5d1, Drer\col12a1b, Drer\ugt5a5, Drer\col27a1a, Drer\ugt8, Drer\adcy3a, Drer\col4a5, Drer\erap2, Drer\adcy5, Drer\ugt5f1, Drer\si:ch211-276a23.5, Drer\col14a1a, Drer\ugt5g1, Drer\adcy2a, Drer\zdhhc15b, Drer\adcy6a, Drer\enpep, Drer\zgc:153049, Drer\erap1b, Drer\ugt5g2, Drer\si:ch211-106j24.1, Drer\col1a1b, Drer\lnpep, Drer\col2a1b, Drer\col1a1a, Drer\LOC101884357, Drer\col9a1b, Drer\zdhhc20a, Drer\zdhhc20b, Drer\col6a2, Drer\si:dkey-225n22.4, Drer\col4a6, Drer\adcy1b, Drer\ugt5c2, Drer\col6a4a, Drer\ugt2b6, Drer\adcy7, Drer\ugt5c3, Drer\ugt5c1, Drer\col5a2b, Drer\ugt1ab, Drer\ugt5e1, Drer\adcy2b, Drer\col6a1, Drer\col28a1a, Drer\ugt2a6, Drer\LOC100538221, Drer\ugt5a1, Drer\si:ch211-149p5.1, Drer\anpepa, Drer\ugt2b1, Drer\LOC101883924, Drer\col4a2, Drer\si:ch211-198g19.1, Drer\col17a1b, Drer\erap1a, Drer\si:dkey-61l1.4, Drer\col16a1, Drer\col11a1b, Drer\anpepb, Drer\ugt1b7, Drer\ugt2b3, Drer\adcy1a, Drer\col9a1a, Drer\col2a1a, Drer\col9a2, Drer\ugt5b2, Drer\ugt5b3, Drer\zgc:172315, Drer\zdhhc2, Drer\adcy6b, Drer\npepps, Drer\col11a2, Drer\col1a2, Drer\col11a1a, Drer\ugt2a5, Drer\col6a3, Drer\col5a2a, Drer\col5a1, Drer\si:ch211-132f19.7, Drer\si:ch211-106n13.3, Drer\wu:fc38h03, Drer\si:dkey-206f10.1, Drer\col27a1b, Drer\col7a1l, Drer\ugt2a2, Drer\si:ch211-196i2.1, Drer\adcy8, Drer\ugt2b5" "Scer\APE2, Scer\TMA108, Scer\PFA3, Scer\ATG26, Scer\AAP1" "Cele\acy-4, Cele\acy-2" "Xtro\col11a2, Xtro\col3a1, Xtro\col14a1, Xtro\col4a2, Xtro\ugt2b4, Xtro\col1a1, Xtro\lnpep, Xtro\ugt8, Xtro\col4a1, Xtro\col5a1, Xtro\col2a1, Xtro\LOC100486063, Xtro\erap1, Xtro\lvrn, Xtro\adcy6, Xtro\ugt1a6, Xtro\anpep, Xtro\col4a6, Xtro\ugt3a2, Xtro\col1a2, Xtro\adcy1, Xtro\col6a2, Xtro\adcy4, Xtro\enpep, Xtro\dnajc27, Xtro\zdhhc20, Xtro\pqlc2l, Xtro\npepps, Xtro\col27a1, Xtro\col4a5, Xtro\col24a1, Xtro\ugt2a1, Xtro\zdhhc15, Xtro\zdhhc2, Xtro\col7a1, Xtro\adcy7" "Mmus\Ugt1a6b, Mmus\Col4a4, Mmus\Ugt2b5, Mmus\Enpep, Mmus\Col4a5, Mmus\Col9a1, Mmus\Col14a1, Mmus\4933412E24Rik, Mmus\Vwa2, Mmus\Ugt2b1, Mmus\Col4a1, Mmus\Col13a1, Mmus\Col22a1, Mmus\Ugt2b37, Mmus\Col6a4, Mmus\Ugt2b34, Mmus\Ugt2b36, Mmus\Npepps, Mmus\Adcy4, Mmus\Col24a1, Mmus\Col17a1, Mmus\Col4a6, Mmus\Adcy1, Mmus\Col6a3, Mmus\Adcy8, Mmus\Col1a2, Mmus\Ugt2b38, Mmus\Adcy7, Mmus\Adcy6, Mmus\Trhde, Mmus\Col5a1, Mmus\Adcy2, Mmus\Ugt2a1, Mmus\Col9a3, Mmus\Ugt3a1, Mmus\Adcy3, Mmus\Col19a1, Mmus\Col4a2, Mmus\Col7a1, Mmus\Lvrn, Mmus\Col1a1, Mmus\Col23a1, Mmus\Anpep, Mmus\Col2a1, Mmus\Zdhhc15, Mmus\Ugt1a1, Mmus\Ugt2a3, Mmus\Lnpep, Mmus\Col28a1, Mmus\Col11a2, Mmus\8030474K03Rik, Mmus\Col16a1, Mmus\Col6a1, Mmus\Col27a1, Mmus\Ugt2b35, Mmus\Vwa1, Mmus\Tnn, Mmus\Col4a3, Mmus\Col5a2, Mmus\Col6a6, Mmus\Adcy5, Mmus\Col20a1, Mmus\Col5a3, Mmus\Col11a1, Mmus\Col3a1, Mmus\Ugt3a2, Mmus\Col25a1, Mmus\Erap1, Mmus\Ugt8a, Mmus\Zdhhc2, Mmus\Col6a5, Mmus\Zdhhc20" "Hsap\TRHDE, Hsap\UGT2B11, Hsap\ADCY7, Hsap\UGT2A3, Hsap\NPEPPS, Hsap\ADCY3, Hsap\ENPEP, Hsap\LVRN, Hsap\ADCY5, Hsap\UGT2A2, Hsap\COL5A1, Hsap\ZDHHC15, Hsap\ERAP1, Hsap\UGT1A3, Hsap\COL11A2, Hsap\COL17A1, Hsap\COL6A3, Hsap\COL1A1, Hsap\COL23A1, Hsap\VWA1, Hsap\UGT1A1, Hsap\COL4A4, Hsap\COL4A2, Hsap\VWA2, Hsap\COL4A3, Hsap\COL20A1, Hsap\UGT2B17, Hsap\ADCY8, Hsap\UGT2B10, Hsap\COL4A6, Hsap\ERAP2, Hsap\COL9A1, Hsap\UGT8, Hsap\UGT2B28, Hsap\COL6A6, Hsap\COL19A1, Hsap\ADCY2, Hsap\COL16A1, Hsap\ANPEP, Hsap\COL4A5, Hsap\UGT2B7, Hsap\COL5A3, Hsap\COL2A1, Hsap\COL25A1, Hsap\COL9A3, Hsap\ZDHHC2, Hsap\COL9A2, Hsap\COL6A5, Hsap\COL5A2, Hsap\LNPEP, Hsap\ZDHHC20, Hsap\COL14A1, Hsap\UGT3A1, Hsap\COL6A1, Hsap\COL11A1, Hsap\COLQ, Hsap\ADCY1, Hsap\COL3A1, Hsap\COL1A2, Hsap\COL4A1, Hsap\UGT2B15, Hsap\ADCY4, Hsap\COL7A1, Hsap\COL27A1, Hsap\COL24A1, Hsap\COL22A1, Hsap\UGT3A2, Hsap\UGT2B4, Hsap\ADCY6" " larval stage , adult stage , embryonic stage " " adult stage , embryonic stage | 10-18 hr " " optic lobe neuron

, antennal lobe

, adult head

, neuropil

, subesophageal ganglion

, adult brain

, antenna

" "locomotor rhythm defective,viable,fertile" FBgn0034483 CG16894 - http://flybase.org/reports/FBgn0034483 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 histone ubiquitination ; GO:0016574 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000630652 HULC complex ; GO:0033503 | inferred from biological aspect of ancestor with PANTHER:PTN000630652 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 CG16894 "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG16894 11-Aug-17 DroID_v2017_08 Drer\aktip Scer\RAD6 Cele\ubc-19 Xtro\aktip Mmus\Aktip Hsap\AKTIP viable FBgn0266362 CR45010 - http://flybase.org/reports/FBgn0266362 non_protein_coding_gene - - - CR45010 - CR45010 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262405 mir-998 mir-998 stem loop http://flybase.org/reports/FBgn0262405 miRNA_gene - positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | inferred from genetic interaction with Egfr inferred from genetic interaction with Cbl negative regulation of cell death ; GO:0060548 | inferred from genetic interaction with Rbf - "mir-998, miR-998, 998, CR42948, dme-miR-998-3p, dme-miR-998" - CR42948 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052487 CG32487 - http://flybase.org/reports/FBgn0052487 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with SGD:S000002395 phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000002395 dephosphorylation ; GO:0016311 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002395 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000445812 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002395 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002395 "CG2077, CG32487, Phos32487, 24656330" "IPR006349:2-phosphoglycolate phosphatase, eukaryotic, IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG32487 11-Aug-17 DroID_v2017_08 "Drer\pgp, Drer\pdxp" Scer\PHO13 "Cele\C53A3.2, Cele\K02D10.1, Cele\F44E7.2, Cele\K09H11.7, Cele\C45E5.1" - "Mmus\Pgp, Mmus\Pdxp" "Hsap\PGP, Hsap\PDXP" viable FBgn0058128 CG40128 - http://flybase.org/reports/FBgn0058128 protein_coding_gene - - - CG40128 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036889 CG14100 - http://flybase.org/reports/FBgn0036889 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001537 RNA methyltransferase activity ; GO:0008173 | inferred from electronic annotation with InterPro:IPR001537 RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR001537 microtubule associated complex ; GO:0005875 | inferred from direct assay CG14100 "IPR001537:tRNA/rRNA methyltransferase, SpoU type, IPR013123:RNA 2-O ribose methyltransferase, substrate binding, IPR029028:Alpha/beta knot methyltransferases, IPR029064:50S ribosomal protein L30e-like, IPR029026:tRNA (guanine-N1-)-methyltransferase, N-terminal" CG14100 11-Aug-17 DroID_v2017_08 "Drer\rnmtl1b, Drer\rnmtl1a" Scer\MRM1 - Xtro\rnmtl1 Mmus\Rnmtl1 Hsap\MRM3 viable FBgn0025693 ZnT41F Zinc transporter 41F http://flybase.org/reports/FBgn0025693 FBgn0033040 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0010312 zinc ion transmembrane transporter activity ; GO:0005385 | inferred from sequence or structural similarity with SGD:S000005843 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002524 regulation of sequestering of zinc ion ; GO:0061088 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype response to zinc ion ; GO:0010043 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 zinc II ion transport ; GO:0006829 | inferred from sequence or structural similarity with SGD:S000005843 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002524 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 "CG11163, CK02137, BEST:CK02137, dZnT41F, ZnT41F, cg11163, dZNT41F" "IPR002524:Cation efflux protein, IPR027470:Cation efflux protein, cytoplasmic domain" CG11163 11-Aug-17 DroID_v2017_08 "Drer\slc30a2, Drer\slc30a1a, Drer\slc30a4, Drer\slc30a8, Drer\slc30a1b" "Scer\ZRC1, Scer\COT1" "Cele\cdf-1, Cele\cdf-2, Cele\ttm-1" "Xtro\slc30a2, Xtro\slc30a4, Xtro\slc30a8, Xtro\slc30a3" "Mmus\Slc30a8, Mmus\Slc30a3, Mmus\Slc30a2, Mmus\Slc30a10, Mmus\Slc30a1, Mmus\Slc30a4" "Hsap\SLC30A4, Hsap\SLC30A10, Hsap\SLC30A8, Hsap\SLC30A1, Hsap\SLC30A3, Hsap\SLC30A2" "viable,fertile" FBgn0265835 CG44624 - http://flybase.org/reports/FBgn0265835 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44624 - CG44624 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050393 CG30393 - http://flybase.org/reports/FBgn0050393 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15662, CG30393" - CG30393 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0000972 fs(2)HO3 female sterile (2) HO3 http://flybase.org/reports/FBgn0000972 - gene - - - "fs(2)3A, fs(1)3A, fs(2)HO3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069451 E(br)160 E(br)160 http://flybase.org/reports/FBgn0069451 gene - - - E(br)160 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261955 kdn knockdown http://flybase.org/reports/FBgn0261955 protein_coding_gene citrate (Si)-synthase activity ; GO:0004108 | inferred from sequence or structural similarity with UniProtKB:O75390 citrate (Si)-synthase activity ; GO:0004108 | inferred from direct assay tricarboxylic acid cycle ; GO:0006099 | inferred from electronic annotation with InterPro:IPR019810 citrate metabolic process ; GO:0006101 | inferred from electronic annotation with InterPro:IPR010109 carbohydrate metabolic process ; GO:0005975 | inferred from sequence or structural similarity with UniProtKB:O75390 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:O75390 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG3861, kdn, l(1)G0030, CS, Csyn, l(1)G0033, l(1)G0159, BEST:GM01832, CG 3861, l (1) G0030, Kdn" "IPR016143:Citrate synthase-like, small alpha subdomain, IPR010109:Citrate synthase, eukaryotic-type, IPR002020:Citrate synthase, IPR016142:Citrate synthase-like, large alpha subdomain, IPR019810:Citrate synthase active site" CG3861 11-Aug-17 DroID_v2017_08 Drer\cs "Scer\CIT1, Scer\CIT2, Scer\CIT3" Cele\cts-1 Xtro\cs "Mmus\Csl, Mmus\Cs" Hsap\CS FBgn0015075 Ddx1 Dead-box-1 http://flybase.org/reports/FBgn0015075 FBgn0013790 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nuclease activity ; GO:0004518 | inferred from sequence or structural similarity with UniProtKB:Q92499 poly(A) binding ; GO:0008143 | inferred from sequence or structural similarity with UniProtKB:Q92499 DNA/RNA helicase activity ; GO:0033677 | inferred from sequence or structural similarity with UniProtKB:Q92499 helicase activity ; GO:0004386 | inferred from sequence or structural similarity transcription cofactor activity ; GO:0003712 | inferred from sequence or structural similarity with UniProtKB:Q92499 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ATP-dependent helicase activity ; GO:0008026 | inferred from sequence or structural similarity with UniProtKB:Q92499 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with UniProtKB:Q92499 embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from expression pattern ribosome biogenesis ; GO:0042254 | inferred from sequence or structural similarity with UniProtKB:Q92499 DNA duplex unwinding ; GO:0032508 | inferred from sequence or structural similarity with UniProtKB:Q92499 oogenesis ; GO:0048477 | inferred from mutant phenotype RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 spermatogenesis ; GO:0007283 | inferred from mutant phenotype double-strand break repair ; GO:0006302 | inferred from sequence or structural similarity with UniProtKB:Q92499 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q92499 "DDX1, DmRH12, DmDDX1, anon-79E, Dbp79E, CG9054, Ddx1" "IPR001650:Helicase, C-terminal, IPR003877:SPRY domain, IPR011545:DEAD/DEAH box helicase domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR001870:B30.2/SPRY domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9054 11-Aug-17 DroID_v2017_08 Drer\ddx1 "Scer\DBP1, Scer\DED1" "Cele\tofu-2, Cele\Y55F3BR.1" Xtro\ddx1 Mmus\Ddx1 Hsap\DDX1 embryonic stage -- adult stage organism

"viable,fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0062260 Rasta Rasta http://flybase.org/reports/FBgn0062260 gene - - - Rasta - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046879 Obp56c Odorant-binding protein 56c http://flybase.org/reports/FBgn0046879 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "56c, CG15129, OBP56c, CG30128, Obp56c, DmelObp56c" IPR006170:Pheromone/general odorant binding protein CG30128 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030073 CG10962 - http://flybase.org/reports/FBgn0030073 protein_coding_gene - - - "EP(X)1565, CG7090, BcDNA:RE29909, EP1565, CG10962" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG10962 11-Aug-17 DroID_v2017_08 "Drer\dhrs11a, Drer\zgc:92630, Drer\dhrs11b, Drer\zgc:153724" "Scer\YMR226C, Scer\TSC10" "Cele\H04M03.3, Cele\T01G6.10" Xtro\dhrs11 "Mmus\Dhrs11, Mmus\Kdsr" "Hsap\KDSR, Hsap\DHRS11" "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0070035 966 966 http://flybase.org/reports/FBgn0070035 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available 966 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085203 CG34174 - http://flybase.org/reports/FBgn0085203 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34174 - CG34174 11-Aug-17 DroID_v2017_08 Drer\cinp - - Xtro\cinp Mmus\Cinp Hsap\CINP FBgn0040391 CG2854 - http://flybase.org/reports/FBgn0040391 protein_coding_gene - - - "EG:BACH48C10.2, CG2854" "IPR027986:T-cell activation inhibitor, mitochondrial, IPR027989:Domain of unknown function DUF4461, IPR028031:Domain of unknown function DUF4460" CG2854 11-Aug-17 DroID_v2017_08 Drer\tcaim - Cele\C35B8.3 Xtro\tcaim Mmus\Tcaim Hsap\TCAIM viable FBgn0028208 l(3)S011028 lethal (3) S011028 http://flybase.org/reports/FBgn0028208 gene - - - "0110/28, l(3)S011028" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037432 CG10298 - http://flybase.org/reports/FBgn0037432 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG10298, BcDNA:GH28351" "IPR001858:Phosphatidylethanolamine-binding, conserved site, IPR008914:Phosphatidylethanolamine-binding protein" CG10298 11-Aug-17 DroID_v2017_08 "Drer\mrpl38, Drer\pebp1, Drer\pebp4" "Scer\TFS1, Scer\YLR179C, Scer\MRPL35" "Cele\F40A3.3, Cele\Y69E1A.5" "Xtro\mrpl38, Xtro\pebp4, Xtro\pebp1" "Mmus\Pbp2, Mmus\Pebp1, Mmus\Pebp4, Mmus\Mrpl38" "Hsap\PEBP4, Hsap\MRPL38, Hsap\PEBP1" viable FBgn0060793 l(3)S058507b lethal (3) S058507b http://flybase.org/reports/FBgn0060793 gene - - - "0585/07, l(3)S058507b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0020827 l(2)WO "Wooster, Ohio" http://flybase.org/reports/FBgn0020827 - gene - - - l(2)WO - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024264 acd(2)5L3 auditory courtship defective 5L3 http://flybase.org/reports/FBgn0024264 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "5L3, acd(2)5L3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective,courtship behavior defective,male,male fertile" FBgn0267644 CR45982 - http://flybase.org/reports/FBgn0267644 non_protein_coding_gene - - - CR45982 - CR45982 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022735 hypnos-3 "hypoxia, anoxia, sensitive 3" http://flybase.org/reports/FBgn0022735 - gene - response to hypoxia ; GO:0001666 | traceable author statement - hypnos-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,dominant,behavior defective,recessive" adult central nervous system FBgn0003370 sge shifted genitals http://flybase.org/reports/FBgn0003370 - gene - - - sge - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective,male sterile,viable,male,reduced" "genitalia,anal plate,wing,eye" FBgn0030787 CG9609 - http://flybase.org/reports/FBgn0030787 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG9609 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG9609 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-208k4.2, Drer\LOC568955, Drer\gtf3ab, Drer\si:dkey-156n14.3, Drer\gtf3aa" "Scer\SWI5, Scer\ACE2, Scer\PZF1" "Cele\F10B5.3, Cele\F21A9.2, Cele\Y55F3AM.14, Cele\pqm-1" "Xtro\zxdc, Xtro\gtf3a, Xtro\42Sp43" "Mmus\Zxdc, Mmus\Zxdb, Mmus\Gtf3a, Mmus\Zfp961" "Hsap\ZNF557, Hsap\ZXDB, Hsap\GTF3A, Hsap\ZXDA, Hsap\ZXDC" viable DRSC20199 K 0.264848805 -0.478915076 0.331729031 1.101772272 1.874208159 -1.005765552 FBgn0003585 Su(var) Suppressor of variegation http://flybase.org/reports/FBgn0003585 - gene - - - "Su-V, Su(var), Su_var" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male fertile,female fertile,reduced,suppressor of variegation,enhancer of variegation" FBgn0264825 CR44033 - http://flybase.org/reports/FBgn0264825 non_protein_coding_gene - - - "CR44033, lincRNA.825" - CR44033 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030386 CG2574 - http://flybase.org/reports/FBgn0030386 protein_coding_gene - protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:12478 cellular_component ; GO:0005575 | no biological data available "bs21b01.y1, CG2574" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG2574 11-Aug-17 DroID_v2017_08 "Drer\ube2d3, Drer\ube2nb, Drer\ube2d1b, Drer\ube2t, Drer\ube2e3, Drer\ube2d2, Drer\ube2e2, Drer\ube2na, Drer\ube2e1, Drer\ube2d4, Drer\ube2d1a" "Scer\UBC13, Scer\UBC4, Scer\PEX4, Scer\UBC5" - "Xtro\ube2n, Xtro\ube2d1, Xtro\ube2d4, Xtro\ube2e1, Xtro\ube2e3, Xtro\ube2e2, Xtro\ube2d3" "Mmus\Ube2t, Mmus\Ube2e3, Mmus\Ube2n, Mmus\Ube2dnl2, Mmus\Ube2e1, Mmus\Ube2d1, Mmus\Ube2dnl1, Mmus\Ube2d3, Mmus\Ube2e2, Mmus\Ube2d2b" "Hsap\UBE2D2, Hsap\UBE2D1, Hsap\UBE2D4, Hsap\UBE2E2, Hsap\UBE2Q2L, Hsap\UBE2E1, Hsap\UBE2E3, Hsap\UBE2NL, Hsap\UBE2N, Hsap\UBE2D3, Hsap\UBE2T" viable FBgn0039070 CG17083 - http://flybase.org/reports/FBgn0039070 protein_coding_gene - outer dynein arm assembly ; GO:0036158 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 cilium movement ; GO:0003341 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 outer dynein arm ; GO:0036157 | inferred from electronic annotation with InterPro:IPR029652 axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 CG17083 IPR029652:ODA1/DCC2 family CG17083 11-Aug-17 DroID_v2017_08 Drer\ccdc114 - - Xtro\ccdc63 "Mmus\Ccdc63, Mmus\Ccdc114" "Hsap\CCDC114, Hsap\CCDC63" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0267232 CR45672 - http://flybase.org/reports/FBgn0267232 non_protein_coding_gene - - - CR45672 - CR45672 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028170 l(3)S027403b lethal (3) S027403b http://flybase.org/reports/FBgn0028170 gene - - - "0274/03, l(3)S027403, l(3)S027403b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0267430 Pzl Piezo-like http://flybase.org/reports/FBgn0267430 protein_coding_gene mechanically-gated ion channel activity ; GO:0008381 | inferred from electronic annotation with InterPro:IPR027272 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR027272 cellular_component ; GO:0005575 | no biological data available "Pzl, CG42617, CG40249, CG40188, CG42618, CG41369, CG41238, CG41056, CG40328, CG40232, CR41056, CG45783" "IPR031805:Piezo domain, IPR027272:Piezo family, IPR031334:Piezo non-specific cation channel, R-Ras-binding domain" CG45783 11-Aug-17 DroID_v2017_08 "Drer\piezo2, Drer\piezo1, Drer\LOC100334952, Drer\si:dkey-11f4.7" - Cele\pezo-1 Xtro\piezo1 "Mmus\Piezo2, Mmus\Piezo1" "Hsap\PIEZO2, Hsap\PIEZO1" FBgn0265909 CR44698 - http://flybase.org/reports/FBgn0265909 non_protein_coding_gene - - - "lincRNA.39, CR44698" - CR44698 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283427 FASN1 Fatty acid synthase 1 http://flybase.org/reports/FBgn0283427 protein_coding_gene "oleoyl-[acyl-carrier-protein] hydrolase activity ; GO:0004320 | inferred from electronic annotation with InterPro:IPR023102 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity ; GO:0004316 | inferred from electronic annotation with InterPro:IPR023102 palmitoyl-[acyl-carrier-protein] hydrolase activity ; GO:0016296 | inferred from electronic annotation with InterPro:IPR023102 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity ; GO:0004319 | inferred from electronic annotation with InterPro:IPR023102 myristoyl-[acyl-carrier-protein] hydrolase activity ; GO:0016295 | inferred from electronic annotation with InterPro:IPR023102 [acyl-carrier-protein] S-malonyltransferase activity ; GO:0004314 | inferred from electronic annotation with InterPro:IPR023102 [acyl-carrier-protein] S-acetyltransferase activity ; GO:0004313 | inferred from electronic annotation with InterPro:IPR023102 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity ; GO:0004317 | inferred from electronic annotation with InterPro:IPR023102 3-oxoacyl-[acyl-carrier-protein] synthase activity ; GO:0004315 | inferred from electronic annotation with InterPro:IPR023102 phosphopantetheine binding ; GO:0031177 | inferred from electronic annotation with InterPro:IPR020806 fatty acid synthase activity ; GO:0004312 | inferred from direct assay" response to sucrose ; GO:0009744 | inferred from mutant phenotype triglyceride biosynthetic process ; GO:0019432 | inferred from mutant phenotype glycogen metabolic process ; GO:0005977 | inferred from mutant phenotype cellular response to sucrose stimulus ; GO:0071329 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "FASN[CG3523], FAS, CG3523, Fatty acid synthase, BcDNA:gh07626, DM_7295848, BcDNA:GH07626, anon-EST:Posey43, anon-EST:Posey235, anon-WO0138581.1, dFAS, fas, FASN, Fas, FAS[CG3523], FASN1, Fasn" "IPR032821:Ketoacyl-synthetase, C-terminal extension, IPR020807:Polyketide synthase, dehydratase domain, IPR001031:Thioesterase, IPR009081:Phosphopantetheine binding ACP domain, IPR013149:Alcohol dehydrogenase, C-terminal, IPR018201:Beta-ketoacyl synthase, active site, IPR011032:GroES-like, IPR014030:Beta-ketoacyl synthase, N-terminal, IPR014031:Beta-ketoacyl synthase, C-terminal, IPR014043:Acyl transferase, IPR016040:NAD(P)-binding domain, IPR016035:Acyl transferase/acyl hydrolase/lysophospholipase, IPR016036:Malonyl-CoA ACP transacylase, ACP-binding, IPR016039:Thiolase-like, IPR020843:Polyketide synthase, enoylreductase domain, IPR029058:Alpha/Beta hydrolase fold, IPR023102:Fatty acid synthase, domain 2, IPR013968:Polyketide synthase, ketoreductase domain, IPR020841:Polyketide synthase, beta-ketoacyl synthase domain, IPR020801:Polyketide synthase, acyl transferase domain, IPR020806:Polyketide synthase, phosphopantetheine-binding domain" CG3523 11-Aug-17 DroID_v2017_08 "Drer\fasn, Drer\si:dkey-61p9.11" Scer\CEM1 "Cele\C41A3.1, Cele\fasn-1, Cele\F32H2.6" Xtro\fasn Mmus\Fasn Hsap\FASN "visible,viable,increased cell death,lethal,conditional" "wing,embryonic/larval hemolymph | third instar larval stage" DRSC00268 IE -0.278339281 2.095959839 1.070689429 -3.689618051 0.201414598 -0.961430827 FBgn0266615 CG45122 - http://flybase.org/reports/FBgn0266615 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45122 - CG45122 11-Aug-17 DroID_v2017_08 - - - - - Hsap\SMKR1 FBgn0001328 ks-2 male fertility factor ks2 http://flybase.org/reports/FBgn0001328 - gene - - - "ks2, Sms2, ks-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile testis FBgn0011633 l(2)T57h6 lethal (2) T57h6 http://flybase.org/reports/FBgn0011633 FBgn0005177 gene - - - l(2)T57h6 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002936 ninaA neither inactivation nor afterpotential A http://flybase.org/reports/FBgn0002936 - protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | traceable author statement peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from sequence or structural similarity with protein_id:CAA68264 cyclosporin A binding ; GO:0016018 | inferred from mutant phenotype "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ; GO:0070059 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | traceable author statement photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | non-traceable author statement phototransduction ; GO:0007602 | inferred from mutant phenotype phototransduction ; GO:0007602 | traceable author statement N-glycan processing ; GO:0006491 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from physical interaction with ninaE transport ; GO:0006810 | traceable author statement phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype rhodopsin metabolic process ; GO:0046154 | inferred from mutant phenotype protein deglycosylation ; GO:0006517 | inferred from mutant phenotype 'de novo' protein folding ; GO:0006458 | traceable author statement" rhabdomere ; GO:0016028 | NOT inferred from direct assay nuclear membrane ; GO:0031965 | NOT inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay endoplasmic reticulum lumen ; GO:0005788 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "ninA, CG3966, ninaA, NinaA, NINAA" "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG3966 11-Aug-17 DroID_v2017_08 "Drer\ppig, Drer\ppiaa, Drer\LOC100333141, Drer\si:ch1073-55a19.2, Drer\nktr, Drer\ppid, Drer\ppiab, Drer\ppih, Drer\ppib, Drer\ppil6, Drer\ppie" "Scer\CPR8, Scer\CPR2, Scer\CPR5, Scer\CPR4" "Cele\cyn-9, Cele\cyn-1, Cele\cyn-5, Cele\cyn-3, Cele\cyn-8, Cele\cyn-2, Cele\cyn-6, Cele\cyn-11" "Xtro\ppid, Xtro\ppih, Xtro\ppib, Xtro\ppil6, Xtro\nktr, Xtro\ppic, Xtro\ppia, Xtro\ppie, Xtro\ranbp2" "Mmus\Ppic, Mmus\Ppil6, Mmus\Ranbp2, Mmus\Ppid, Mmus\Ppie, Mmus\Ppib, Mmus\Nktr, Mmus\Ppif, Mmus\Ppih, Mmus\Ppig, Mmus\Ppia" "Hsap\PPIAL4D, Hsap\PPID, Hsap\PPIG, Hsap\PPIL6, Hsap\NKTR, Hsap\RGPD6, Hsap\PPIAL4G, Hsap\PPIH, Hsap\RGPD5, Hsap\PPIA, Hsap\RGPD4, Hsap\RANBP2, Hsap\RGPD1, Hsap\PPIB, Hsap\RGPD8, Hsap\PPIC, Hsap\PPIE, Hsap\RGPD3, Hsap\PPIF, Hsap\PPIAL4A, Hsap\LOC105371242, Hsap\RGPD2, Hsap\PPIAL4C" " pupal stage | late , adult stage " adult head

"visible,recessive,neurophysiology defective,wild-type,heat sensitive,cold sensitive,increased cell death" "photoreceptor cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,retina,conditional,photoreceptor cell & endoplasmic reticulum,ommatidium" FBgn0053743 snmRNA:430:CR33743 snmRNA:430:CR33743 http://flybase.org/reports/FBgn0053743 non_protein_coding_gene - - - "CR33743, snmRNA:430:CR33743" - CR33743 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022286 l(2)254 lethal (2) 254 http://flybase.org/reports/FBgn0022286 - gene - - - "254, l(2)254" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032956 Cul2 Cullin 2 http://flybase.org/reports/FBgn0032956 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000231993 ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Roc1a "protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000231993 growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype negative regulation of BMP signaling pathway ; GO:0030514 | inferred from mutant phenotype inferred from genetic interaction with dpp inferred from genetic interaction with tkv regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred by curator from GO:0031462,GO:0031625 germ cell development ; GO:0007281 | inferred from mutant phenotype male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype" perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay Cul2-RING ubiquitin ligase complex ; GO:0031462 | inferred from direct assay "CUL2, CG1512, Cul2, l(2)02074, DMcul-2, Cul-2, cul-2, Cullin2, Cullin 2, cul2, dCul2" "IPR001373:Cullin, N-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016157:Cullin, conserved site, IPR016158:Cullin homology, IPR016159:Cullin repeat-like-containing domain, IPR019559:Cullin protein, neddylation domain" CG1512 11-Aug-17 DroID_v2017_08 Drer\cul2 "Scer\CDC53, Scer\CUL3" Cele\cul-2 Xtro\cul2 Mmus\Cul2 Hsap\CUL2 "fertile,lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable,female sterile,recessive" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,NMJ bouton,supernumerary,egg chamber,interfollicle cell,nurse cell,oocyte,germarium,terminal filament" FBgn0250838 roh reduction of Rh1 http://flybase.org/reports/FBgn0250838 protein_coding_gene - rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype - "CG3487, anon-SAGE:Wang-079, CG30415, roh" - CG30415 11-Aug-17 DroID_v2017_08 - - - - - - DRSC04003 K -1.20318073 -1.200392626 -0.730692694 -0.405500764 1.838270475 0.463103706 FBgn0021794 l(2)k17019b lethal (2) k17019b http://flybase.org/reports/FBgn0021794 - gene - - - l(2)k17019b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058385 CG40385 - http://flybase.org/reports/FBgn0058385 protein_coding_gene - - - CG40385 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014386 slk schluckless http://flybase.org/reports/FBgn0014386 - gene - - - slk - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038590 CG12320 - http://flybase.org/reports/FBgn0038590 protein_coding_gene - spliceosomal tri-snRNP complex assembly ; GO:0000244 | inferred from biological aspect of ancestor with PANTHER:PTN000294070 cytoplasm ; GO:0005737 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from physical interaction with Prp8 "CG12320, Aar2" "IPR007946:A1 cistron-splicing factor, AAR2, IPR033648:AAR2, C-terminal, IPR033647:AAR2, N-terminal" CG12320 11-Aug-17 DroID_v2017_08 Drer\aar2 Scer\AAR2 Cele\F10B5.2 Xtro\aar2 Mmus\Aar2 Hsap\AAR2 "viable,visible" trichogen cell FBgn0019758 l(1)75B2 lethal (1) 75B2 http://flybase.org/reports/FBgn0019758 - gene - - - l(1)75B2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051872 CG31872 - http://flybase.org/reports/FBgn0051872 protein_coding_gene - lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG17101, CG17093, CG31872" "IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG31872 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH1, Scer\YEH2, Scer\TGL1" "Cele\lipl-6, Cele\lipl-2, Cele\lipl-7, Cele\lipl-1, Cele\lipl-4, Cele\lipl-3, Cele\lipl-8, Cele\lipl-5" Xtro\lipa "Mmus\Lipo3, Mmus\Lipm, Mmus\Lipf, Mmus\Lipo1, Mmus\Lipo4, Mmus\Lipo2, Mmus\Lipk, Mmus\Lipa, Mmus\Lipn" "Hsap\LIPJ, Hsap\LIPN, Hsap\LIPM, Hsap\LIPF, Hsap\LIPK, Hsap\LIPA" viable FBgn0260272 GSd422 - http://flybase.org/reports/FBgn0260272 gene - - - GSd422 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024483 Cir Cir http://flybase.org/reports/FBgn0024483 - gene - - cellular_component ; GO:0005575 | no biological data available "DCIR, Cir" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030744 CG9992 - http://flybase.org/reports/FBgn0030744 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9992 - CG9992 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063889 anon-10Eb anon-10Eb http://flybase.org/reports/FBgn0063889 gene - - - anon-10Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028188 l(3)S023635 lethal (3) S023635 http://flybase.org/reports/FBgn0028188 gene - - - "0726/03, 0553/10, 0236/35, l(3)S023635" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0283494 Adk2 Adenylate kinase 2 http://flybase.org/reports/FBgn0283494 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850, InterPro:IPR006259 adenylate kinase activity ; GO:0004017 | inferred from direct assay inferred from mutant phenotype adenylate kinase activity ; GO:0004017 | inferred from sequence or structural similarity with UniProtKB:P54819" ADP biosynthetic process ; GO:0006172 | inferred from sequence or structural similarity with UniProtKB:P54819 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrial intermembrane space ; GO:0005758 | inferred from sequence or structural similarity with UniProtKB:P54819 "l(2)k04201, l(2)04209, l(2)04201, l(2)k04209, Adk2-60B, Adk2, l(2)k16120, Adk2-44B, CG3140, Dak2, ADK-2, anon-Dak2, BcDNA:SD09634" "IPR033690:Adenylate kinase, conserved site, IPR000850:Adenylate kinase/UMP-CMP kinase, IPR006259:Adenylate kinase subfamily, IPR007862:Adenylate kinase, active site lid domain, IPR028587:Adenylate kinase 2, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3140 11-Aug-17 DroID_v2017_08 "Drer\ak7a, Drer\ak2, Drer\ak3, Drer\ak4, Drer\ak8, Drer\si:ch211-199m3.4, Drer\ak7b" "Scer\ADK1, Scer\ADK2" "Cele\let-754, Cele\ZK673.2, Cele\F38E11.6" "Xtro\ak4, Xtro\ak9, Xtro\ak8, Xtro\ak7, Xtro\ak3, Xtro\ak2" "Mmus\Ak2, Mmus\Ak7, Mmus\Ak4, Mmus\Ak8, Mmus\Ak3" "Hsap\AK7, Hsap\AK2, Hsap\AK8, Hsap\AK3, Hsap\AK9, Hsap\AK4" FBgn0082677 E(ftz)5303 E(ftz)5303 http://flybase.org/reports/FBgn0082677 gene - - - "5303, E(ftz)5303" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025632 CG4313 - http://flybase.org/reports/FBgn0025632 - protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "EG:22E5.10, CG4313" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG4313 11-Aug-17 DroID_v2017_08 "Drer\mtnr1ba, Drer\aplnrb, Drer\bdkrb1, Drer\agtr1b, Drer\gpr84, Drer\mtnr1ab, Drer\si:dkey-63b1.1, Drer\agtr1a, Drer\mtnr1bb, Drer\agtr2, Drer\bdkrb2, Drer\aplnra, Drer\gpr25, Drer\aplnr2, Drer\mtnr1aa" - "Cele\npr-15, Cele\npr-29, Cele\npr-30, Cele\npr-33" Xtro\gpr84 "Mmus\Gpr15, Mmus\Aplnr, Mmus\Bdkrb1, Mmus\Agtr1a, Mmus\Agtr1b, Mmus\Gpr50, Mmus\Gpr25, Mmus\Gpr84, Mmus\Agtr2, Mmus\Bdkrb2" "Hsap\GPR15, Hsap\APLNR, Hsap\AGTR2, Hsap\BDKRB1, Hsap\GPR25, Hsap\AGTR1, Hsap\GPR84, Hsap\BDKRB2" FBgn0260260 GSd331 - http://flybase.org/reports/FBgn0260260 gene - - - GSd331 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038140 PK2-R1 Pyrokinin 2 receptor 1 http://flybase.org/reports/FBgn0038140 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity inferred from direct assay pyrokinin receptor activity ; GO:0036401 | inferred from physical interaction with Hug neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "anon-WO0170980.191, anon-WO0170980.190, CG8784, Dm CG8784, PK2-R1" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG8784 11-Aug-17 DroID_v2017_08 "Drer\gpr39, Drer\ghsrb, Drer\ghsra, Drer\ntsr1, Drer\mlnr, Drer\nmur1b, Drer\LOC103910036, Drer\LOC101885849, Drer\nmur1a, Drer\nmur3, Drer\LOC101885494, Drer\LOC101885431" - "Cele\nmur-1, Cele\nmur-2, Cele\npr-32, Cele\nmur-3, Cele\nmur-4" Xtro\nmur2 "Mmus\Ghsr, Mmus\Nmur1, Mmus\Nmur2, Mmus\Olfr835, Mmus\Ntsr2, Mmus\Gpr39, Mmus\Ntsr1" "Hsap\NTSR2, Hsap\GPR39, Hsap\NMUR2, Hsap\GPR148, Hsap\NMUR1, Hsap\OR7G2, Hsap\GHSR, Hsap\MLNR, Hsap\NTSR1" "viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage" DRSC16447 K 0.515563735 -0.403844144 0.285066669 -0.806803689 3.259555012 2.565470539 FBgn0065642 l(2)SH0757 lethal (2) SH0757 http://flybase.org/reports/FBgn0065642 gene - - - "l(2)SH0757, l(2)SH2 0757" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259336 EP-65 - http://flybase.org/reports/FBgn0259336 gene - - - EP-65 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0264710 CR43979 - http://flybase.org/reports/FBgn0264710 non_protein_coding_gene - - - CR43979 - CR43979 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053258 CG33258 - http://flybase.org/reports/FBgn0053258 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "BP1001, CR33258, CG33258" IPR002557:Chitin binding domain CG33258 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014059 Su(tor)2-56 Su(tor)2-56 http://flybase.org/reports/FBgn0014059 - gene - - - Su(tor)2-56 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044493 DTD45.8 DTD45.8 http://flybase.org/reports/FBgn0044493 gene - - - DTD45.8 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031681 pgant5 polypeptide GalNAc transferase 5 http://flybase.org/reports/FBgn0031681 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement "CG31651, CG9152, l(2)e02157, pgant5, PGANT5" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG31651 11-Aug-17 DroID_v2017_08 "Drer\galnt6, Drer\galnt16, Drer\si:ch211-15e22.3, Drer\galnt7, Drer\wbscr17, Drer\LOC568645, Drer\LOC101886587, Drer\LOC103910015, Drer\galnt3, Drer\LOC100535692, Drer\LOC100334784, Drer\galnt14, Drer\LOC101882942, Drer\galnt10, Drer\galnt1, Drer\galnt18b, Drer\galnt2, Drer\galnt9, Drer\galnt8a.1, Drer\poc1bl, Drer\galnt13, Drer\galnt12, Drer\galnt8b, Drer\galnt11" - "Cele\gly-10, Cele\gly-7, Cele\gly-11, Cele\gly-3, Cele\gly-5, Cele\gly-9" "Xtro\galnt16, Xtro\wbscr17, Xtro\galnt15, Xtro\galnt7, Xtro\galnt13, Xtro\galnt4, Xtro\galnt12, Xtro\galnt9, Xtro\galnt2, Xtro\galnt1, Xtro\galnt6.1, Xtro\galnt14, Xtro\galnt10" "Mmus\Wbscr17, Mmus\Galnt2, Mmus\Galnt9, Mmus\Galnt7, Mmus\Galnt10, Mmus\Galnt18, Mmus\Galnt13, Mmus\Galnt1, Mmus\Galnt6, Mmus\Galntl5, Mmus\Galnt15, Mmus\Galnt12, Mmus\Galnt11, Mmus\Galnt4, Mmus\Galnt3, Mmus\Galnt14, Mmus\Galnt16, Mmus\Galnt5, Mmus\Galntl6" "Hsap\POC1B-GALNT4, Hsap\GALNT6, Hsap\GALNT15, Hsap\GALNT14, Hsap\GALNT5, Hsap\GALNT10, Hsap\GALNT11, Hsap\GALNT13, Hsap\GALNT7, Hsap\GALNT16, Hsap\GALNT12, Hsap\GALNT1, Hsap\GALNT9, Hsap\WBSCR17, Hsap\GALNTL6, Hsap\GALNT2, Hsap\GALNT18, Hsap\GALNT3, Hsap\GALNTL5, Hsap\GALNT8, Hsap\GALNT4" "viable,lethal,recessive,partially lethal - majority die" "embryonic/larval gut,embryonic/larval cuprophilic cell" FBgn0266935 CR45386 - http://flybase.org/reports/FBgn0266935 non_protein_coding_gene - - - "lincRNA.619, CR45386" - CR45386 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015347 anon-87Ae anon-87Ae http://flybase.org/reports/FBgn0015347 - gene - - - "87A7-9/6, anon-87Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036588 CG13068 - http://flybase.org/reports/FBgn0036588 protein_coding_gene - - - CG13068 - CG13068 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially lethal - majority die,some die during pupal stage" FBgn0002472 l(3)SG27 lethal (3) SG27 http://flybase.org/reports/FBgn0002472 FBgn0004716 gene - - - "l(3)ds17, l(3)B17, l(3)SG27" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0266947 CR45398 - http://flybase.org/reports/FBgn0266947 non_protein_coding_gene - - - CR45398 - CR45398 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030481 CG1662 - http://flybase.org/reports/FBgn0030481 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 CG1662 IPR007248:Mpv17/PMP22 CG1662 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-120k19.1, Drer\mpv17l2, Drer\mpv17, Drer\pxmp2" "Scer\SYM1, Scer\YOR292C" "Cele\ZK470.1, Cele\T18D3.9" "Xtro\pxmp2, Xtro\mpv17l2" "Mmus\Mpv17, Mmus\Pxmp2, Mmus\Mpv17l, Mmus\Mpv17l2" "Hsap\MPV17, Hsap\MPV17L2, Hsap\PXMP2, Hsap\MPV17L" "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0040760 CG13181 - http://flybase.org/reports/FBgn0040760 protein_coding_gene - - - CG13181 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036318 Wbp2 WW domain binding protein 2 http://flybase.org/reports/FBgn0036318 protein_coding_gene - "hippo signaling ; GO:0035329 | inferred from genetic interaction with wts inferred from physical interaction with yki positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype inferred from genetic interaction with wts positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "wbp2, Wbp2, CG11009, WWBP" "IPR004182:GRAM domain, IPR011993:PH domain-like" CG11009 11-Aug-17 DroID_v2017_08 "Drer\wbp2nl, Drer\wbp2" - "Cele\D2013.6, Cele\C18B2.4" "Xtro\wbp2, Xtro\wbp2nl" "Mmus\Wbp2, Mmus\Wbp2nl" "Hsap\WBP2NL, Hsap\WBP2" "size defective,viable" wing margin FBgn0002060 l(2)40Fe lethal (2) 40Fe http://flybase.org/reports/FBgn0002060 - gene - - - "40Fe, l(2Lh)Fe, GroupVII, l(2L)D, l(2)40Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" wing FBgn0000245 c curved http://flybase.org/reports/FBgn0000245 - gene - - - "C, c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,dominant" wing FBgn0036438 CG13477 - http://flybase.org/reports/FBgn0036438 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13477 - CG13477 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039680 Cap-D2 CAP-D2 condensin subunit http://flybase.org/reports/FBgn0039680 protein_coding_gene "chromatin binding ; GO:0003682 | inferred by curator from GO:0000793,GO:0000796 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000368592 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000368592" chromosome condensation ; GO:0030261 | inferred from mutant phenotype meiotic chromosome condensation ; GO:0010032 | inferred from biological aspect of ancestor with PANTHER:PTN000368592 ventral cord development ; GO:0007419 | inferred from mutant phenotype chromosome separation ; GO:0051304 | inferred from biological aspect of ancestor with PANTHER:PTN000368592 mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype "cytoplasm ; GO:0005737 | inferred from direct assay condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:24305 nuclear condensin complex ; GO:0000799 | inferred from biological aspect of ancestor with PANTHER:PTN000368592 condensin complex ; GO:0000796 | inferred from direct assay condensed chromosome ; GO:0000793 | colocalizes_with inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay condensed chromosome, centromeric region ; GO:0000779 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay" "CG1911, CAP-D2, CapD2, Cap-D2, DmCAP-D2, dCap-D2" "IPR007673:Condensin subunit 1, IPR032682:Condensin complex subunit 1, C-terminal, IPR016024:Armadillo-type fold, IPR024324:Condensin complex subunit 1, N-terminal, IPR026971:Condensin subunit 1/Condensin-2 complex subunit D3, IPR011989:Armadillo-like helical" CG1911 11-Aug-17 DroID_v2017_08 "Drer\ncapd2, Drer\ncapd3" Scer\YCS4 "Cele\srbc-45, Cele\dpy-28, Cele\hcp-6" "Xtro\ncapd2, Xtro\ncapd3" "Mmus\Ncapd2, Mmus\Ncapd3" Hsap\NCAPD2 "partially lethal - majority die,some die during pupal stage" FBgn0051835 CG31835 - http://flybase.org/reports/FBgn0051835 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BG:DS00810.1, CG31835" "IPR000433:Zinc finger, ZZ-type, IPR008598:Drought induced 19 protein type, zinc-binding domain" CG31835 11-Aug-17 DroID_v2017_08 Drer\kcmf1 - Cele\ZK652.6 Xtro\kcmf1 Mmus\Kcmf1 Hsap\KCMF1 viable FBgn0038609 Nup43 Nucleoporin 43kD http://flybase.org/reports/FBgn0038609 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype nuclear pore outer ring ; GO:0031080 | inferred from biological aspect of ancestor with PANTHER:PTN000505445 nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with HGNC:21182 "Nup43, CG7671, nup43" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7671 11-Aug-17 DroID_v2017_08 Drer\nup43 - Cele\npp-23 Xtro\nup43 Mmus\Nup43 Hsap\NUP43 viable FBgn0065632 l(2)SH0778 lethal (2) SH0778 http://flybase.org/reports/FBgn0065632 gene - - - "l(2)SH0778, l(2)SH2 0778" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267258 CR45694 - http://flybase.org/reports/FBgn0267258 non_protein_coding_gene - - - CR45694 - CR45694 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263332 CR43413 - http://flybase.org/reports/FBgn0263332 non_protein_coding_gene - - - CR43413 - CR43413 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263099 ths::pyr - http://flybase.org/reports/FBgn0263099 engineered_fusion_gene - - - ths::pyr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262895 CR43250 - http://flybase.org/reports/FBgn0262895 non_protein_coding_gene - - - "CG43250, CR43250, lincRNA.587" - CR43250 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001213 hpa hyperantenna http://flybase.org/reports/FBgn0001213 - gene - - - hpa - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,sterile,female sterile,male sterile" "antenna,adult head,eye,wing,macrochaeta" FBgn0070008 BG01428 BG01428 http://flybase.org/reports/FBgn0070008 gene - - - BG01428 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0267194 CR45634 - http://flybase.org/reports/FBgn0267194 non_protein_coding_gene - - - CR45634 - CR45634 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021773 ms(3)P115 ms(3)P115 http://flybase.org/reports/FBgn0021773 - gene - - - ms(3)P115 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0029155 Men-b Malic enzyme b http://flybase.org/reports/FBgn0029155 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NAD+) activity ; GO:0004471 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302, InterPro:IPR015884 malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:0004473 | inferred from biological aspect of ancestor with PANTHER:PTN000601052 malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:0004473 | inferred from sequence or structural similarity with UniProtKB:Q16798" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302, InterPro:IPR015884 malate metabolic process ; GO:0006108 | inferred from sequence or structural similarity with UniProtKB:Q16798 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000601050 pyruvate metabolic process ; GO:0006090 | inferred from biological aspect of ancestor with PANTHER:PTN000601050 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:Q16798 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001157886 "CG5889, MDH, anon-EST:Posey79, Men-b, Mdh" "IPR001891:Malic oxidoreductase, IPR012301:Malic enzyme, N-terminal domain, IPR012302:Malic enzyme, NAD-binding, IPR015884:Malic enzyme, conserved site, IPR016040:NAD(P)-binding domain" CG5889 11-Aug-17 DroID_v2017_08 "Drer\me3, Drer\me1, Drer\me2, Drer\LOC101882012" Scer\MAE1 Cele\men-1 "Xtro\me2, Xtro\me3" "Mmus\Me2, Mmus\Me3, Mmus\Me1" "Hsap\ME1, Hsap\ME3, Hsap\ME2" "viable,fertile" FBgn0038428 CG14894 - http://flybase.org/reports/FBgn0038428 protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from sequence or structural similarity with SGD:S000005065 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with SGD:S000005065 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000005065 CG14894 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1" CG14894 11-Aug-17 DroID_v2017_08 Drer\ttc1 "Scer\TOM70, Scer\CNS1, Scer\SWA2, Scer\TOM71" Cele\C34B2.5 Xtro\ttc1 Mmus\Ttc1 Hsap\TTC1 FBgn0000879 fs(1)M77 female sterile (1) M77 http://flybase.org/reports/FBgn0000879 - gene - - - fs(1)M77 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0032301 CG18561 - http://flybase.org/reports/FBgn0032301 protein_coding_gene - - - CG18561 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02675 IEK -2.026884283 -5.031124483 -1.298633208 -3.993139699 -2.628843078 -0.582459373 FBgn0053111 CG33111 - http://flybase.org/reports/FBgn0053111 protein_coding_gene - - - "CG10193, CG11957, CG11945, CG33111" - CG33111 11-Aug-17 DroID_v2017_08 "Drer\dctn1b, Drer\dctn1a, Drer\si:ch211-1o7.3, Drer\si:dkey-280e21.3, Drer\shtn1" - - - "Mmus\Dctn1, Mmus\Shtn1" "Hsap\SHTN1, Hsap\DCTN1" FBgn0052760 CG32760 - http://flybase.org/reports/FBgn0052760 protein_coding_gene - - - CG32760 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039790 CG2246 - http://flybase.org/reports/FBgn0039790 protein_coding_gene ribose phosphate diphosphokinase activity ; GO:0004749 | inferred from electronic annotation with InterPro:IPR005946 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR005946 nucleotide biosynthetic process ; GO:0009165 | inferred from electronic annotation with InterPro:IPR005946 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000836 - CG2246 "IPR005946:Ribose-phosphate diphosphokinase, IPR029099:Ribose-phosphate pyrophosphokinase, N-terminal domain, IPR029057:Phosphoribosyltransferase-like, IPR000836:Phosphoribosyltransferase domain" CG2246 11-Aug-17 DroID_v2017_08 "Drer\prps1b, Drer\prpsap2, Drer\prpsap1" "Scer\PRS3, Scer\PRS1, Scer\PRS4, Scer\PRS2" Cele\W04G3.5 "Xtro\prpsap1, Xtro\prps1, Xtro\prpsap2, Xtro\prps2" "Mmus\Prpsap2, Mmus\Prps1l1, Mmus\Prps1, Mmus\Prps1l3, Mmus\Prpsap1, Mmus\Prps2" "Hsap\PRPS2, Hsap\PRPS1L1, Hsap\PRPSAP2, Hsap\PRPS1, Hsap\PRPSAP1" "viable,fertile,visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0041127 l(2)45Aj lethal (2) 45Aj http://flybase.org/reports/FBgn0041127 gene - - - l(2)45Aj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive" FBgn0030447 CG2200 - http://flybase.org/reports/FBgn0030447 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR005320 peptidase activity ; GO:0008233 | inferred from biological aspect of ancestor with PANTHER:PTN001073551 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR005320 - CG2200 "IPR005320:Peptidase S51, IPR029062:Class I glutamine amidotransferase-like" CG2200 11-Aug-17 DroID_v2017_08 Drer\si:dkey-69o16.5 - - Xtro\dpepe - - viable FBgn0062706 EP1062 EP1062 http://flybase.org/reports/FBgn0062706 gene - - - "EP(2)1062, EP1062" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013475 l(1)14P11 lethal (1) 14P11 http://flybase.org/reports/FBgn0013475 - gene - - - l(1)14P11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0035011 CG13589 - http://flybase.org/reports/FBgn0035011 protein_coding_gene - - - CG13589 IPR010512:Protein of unknown function DUF1091 CG13589 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069146 mcl(3)Z3946 mcl(3)Z3946 http://flybase.org/reports/FBgn0069146 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3946 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0017398 ftz::Sxl ftz::Sxl http://flybase.org/reports/FBgn0017398 - engineered_fusion_gene - - - ftz::Sxl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085197 CG34168 - http://flybase.org/reports/FBgn0085197 protein_coding_gene - - - "CG34168, CG4959" - CG34168 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0050254 tRNA:Arg-TCT-1-1 transfer RNA:Arginine-TCT 1-1 http://flybase.org/reports/FBgn0050254 tRNA_gene AGA codon-amino acid adaptor activity ; GO:0033447 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033447 cytosol ; GO:0005829 | inferred by curator from GO:0033447 "CR30254, AE002787.trna23-ArgTCT, tRNA:R:TCT:AE002787, chr2R.trna82-ArgTCT, tRNA-Arg-TCT-1-1, tRNA:Arg-TCT-1-1, tRNA:CR30254, AGA" - CR30254 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011079 l(1)Q34 lethal (1) Q34 http://flybase.org/reports/FBgn0011079 FBgn0010210 gene - - - l(1)Q34 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266817 CR45279 - http://flybase.org/reports/FBgn0266817 non_protein_coding_gene - - - CR45279 - CR45279 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267814 CR46139 - http://flybase.org/reports/FBgn0267814 non_protein_coding_gene - - - CR46139 - CR46139 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000738 fs(1)A99 female sterile (1) A99 http://flybase.org/reports/FBgn0000738 - gene - - - "fs(1)99, fs(1)A99" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,cold sensitive,lethal - all die before end of larval stage,rescuable maternal effect,some die during larval stage" FBgn0082969 snoRNA:Psi28S-3316d snoRNA:Psi28S-3316d http://flybase.org/reports/FBgn0082969 snoRNA_gene - - - "snoRNA:Psi28S-3316d, Psi28S-3316d, psi28S-3316d, CR34552" - CR34552 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027528 goe gone early http://flybase.org/reports/FBgn0027528 - protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753 oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of stem cell differentiation ; GO:2000737 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay "BcDNA:LD21405, goe, CG9634" "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain" CG9634 11-Aug-17 DroID_v2017_08 "Drer\ece2b, Drer\phex, Drer\ece1, Drer\mmel1" - "Cele\nep-17, Cele\nep-7, Cele\nep-21, Cele\nep-8, Cele\nep-12, Cele\nep-18, Cele\nep-6, Cele\nep-9, Cele\nep-5, Cele\nep-10, Cele\nep-19, Cele\nep-20, Cele\nep-24, Cele\nep-16, Cele\nep-26, Cele\nep-3, Cele\nep-23, Cele\nep-13" "Xtro\ecel1, Xtro\mmel1, Xtro\ece1, Xtro\ece2" "Mmus\Kel, Mmus\Mme, Mmus\Phex, Mmus\Ecel1, Mmus\Mmel1, Mmus\Ece1, Mmus\Ece2" "Hsap\ECEL1, Hsap\PHEX, Hsap\ECE1, Hsap\KEL, Hsap\MME, Hsap\MMEL1, Hsap\ECE2" "viable,fertile" FBgn0266876 CR45337 - http://flybase.org/reports/FBgn0266876 non_protein_coding_gene - - - CR45337 - CR45337 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264344 CG43800 - http://flybase.org/reports/FBgn0264344 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43800 - CG43800 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035916 GAPsec "GTPase activating protein, SECIS-dependent read-through" http://flybase.org/reports/FBgn0035916 protein_coding_gene GTPase binding ; GO:0051020 | inferred from physical interaction with eEFSec Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 translation elongation factor binding ; GO:0061770 | inferred from physical interaction with eEFSec GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 selenocysteine incorporation ; GO:0001514 | NOT inferred from direct assay regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 translational readthrough ; GO:0006451 | inferred from direct assay regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 cytoplasm ; GO:0005737 | inferred from direct assay "BEST:LD24460, CG5978, dGAPsec, GAPsec" IPR000195:Rab-GTPase-TBC domain CG5978 11-Aug-17 DroID_v2017_08 Drer\tbc1d13 Scer\BUB2 "Cele\tbck-1, Cele\tbc-13" Xtro\tbc1d13 Mmus\Tbc1d13 Hsap\TBC1D13 "viable,fertile" DRSC26128 K -0.104398423 -0.448770259 -0.212651934 -0.282421698 0.188124458 1.631388689 FBgn0264257 Med::smt3 - http://flybase.org/reports/FBgn0264257 engineered_fusion_gene - - - Med::smt3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004182 snRNA:U1:82Ea small nuclear RNA U1 at 82Ea http://flybase.org/reports/FBgn0004182 "FBgn0003915, FBgn0003917" snRNA_gene - - - "U1, U1 snRNA, U1-82.1, U1snRNA, U1b, D.U1-2, U1 82E(pDm6A), K5, snRNA-U1-82.1, U1snRNA82Ea, snRNA:U1, snRNA:U1:82Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053517 Dop2R Dopamine 2-like receptor http://flybase.org/reports/FBgn0053517 protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity with 5-HT7 dopamine neurotransmitter receptor activity, coupled via Gi/Go ; GO:0001591 | inferred from direct assay" anesthesia-resistant memory ; GO:0007615 | inferred from mutant phenotype dopamine receptor signaling pathway ; GO:0007212 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with 5-HT7 integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR000929 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with 5-HT7 integral component of membrane ; GO:0016021 | non-traceable author statement "CG9569, DD2R, CG17004, CG33517, anon-WO0170980.32, anon-WO0170980.31, anon-WO0170980.131, anon-WO0170980.130, D2R, Dop2R, dD2R, d2r" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000929:Dopamine receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG33517 11-Aug-17 DroID_v2017_08 "Drer\drd2b, Drer\drd3, Drer\drd2a, Drer\drd2l, Drer\drd4b, Drer\drd4-rs, Drer\drd4a, Drer\hrh2b" - "Cele\dop-5, Cele\dop-3, Cele\npr-31, Cele\dop-6, Cele\dop-2, Cele\dop-4" Xtro\drd2 "Mmus\Drd3, Mmus\Drd4, Mmus\Drd2, Mmus\Hrh2" "Hsap\DRD2, Hsap\DRD3, Hsap\HRH2, Hsap\DRD4" "locomotor behavior defective,feeding behavior defective,viable" FBgn0085214 CG34185 - http://flybase.org/reports/FBgn0085214 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34185 - CG34185 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027303 l(1)G0123 lethal (1) G0123 http://flybase.org/reports/FBgn0027303 - gene - - - l(1)G0123 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0250848 26-29-p 26-29kD-proteinase http://flybase.org/reports/FBgn0250848 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 microtubule associated complex ; GO:0005875 | inferred from direct assay lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 lipid particle ; GO:0005811 | inferred from direct assay "26-29-p, 26/29kD-proteinase, l(3)s3635, CG8947, anon-SAGE:Wang-123" "IPR025661:Cysteine peptidase, asparagine active site, IPR025660:Cysteine peptidase, histidine active site, IPR000169:Cysteine peptidase, cysteine active site, IPR000668:Peptidase C1A, papain C-terminal, IPR013128:Peptidase C1A, IPR013201:Cathepsin propeptide inhibitor domain (I29)" CG8947 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-269i1.4, Drer\LOC100536033, Drer\zgc:174855, Drer\ctsl.1, Drer\zgc:103438, Drer\cts12, Drer\ctsc, Drer\si:dkey-239j18.2, Drer\ctss1, Drer\si:dkey-239j18.3, Drer\zgc:110239, Drer\si:dkey-228a15.1, Drer\si:dkey-183k8.2, Drer\ctsla, Drer\ctsll, Drer\ctslb, Drer\si:dkey-267n13.1, Drer\wu:fa26c03, Drer\ctss2.1, Drer\ctsz, Drer\LOC100333521, Drer\ctsk, Drer\MGC174155, Drer\ctss2.2, Drer\ctsba, Drer\ctsbb, Drer\ctsh, Drer\zgc:174153" - Cele\tag-196 "Xtro\ctsl, Xtro\LOC100490139, Xtro\ctsb, Xtro\ctsh, Xtro\ctsc, Xtro\ctsz, Xtro\ctsv, Xtro\LOC100498238, Xtro\ctss" "Mmus\Ctsb, Mmus\Ctsz, Mmus\Ctsq, Mmus\Ctss, Mmus\Cts7, Mmus\Ctsr, Mmus\Ctla2a, Mmus\Ctsll3, Mmus\Ctsh, Mmus\Cts8, Mmus\BC051665, Mmus\Cts3, Mmus\Cts6, Mmus\Ctsl, Mmus\4930486L24Rik, Mmus\Ctsk, Mmus\Ctsj, Mmus\Ctsm, Mmus\Ctsc, Mmus\Ctla2b" "Hsap\CTSK, Hsap\CTSV, Hsap\CTSB, Hsap\CTSL, Hsap\CTSC, Hsap\CTSF, Hsap\CTSH, Hsap\CTSZ, Hsap\CTSS" FBgn0025105 CalpI Calpain I http://flybase.org/reports/FBgn0025105 - gene calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay - CalpI - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264871 CR44062 - http://flybase.org/reports/FBgn0264871 non_protein_coding_gene - - - CR44062 - CR44062 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267507 pre-rRNA:CR45847 ribosomal RNA primary transcript:CR45847 http://flybase.org/reports/FBgn0267507 rRNA_gene - - - "pre-rRNA:CR45847, CR45847" - CR45847 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002307 l(3)84Ce lethal (3) 84Ce http://flybase.org/reports/FBgn0002307 - gene - - - l(3)84Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,locomotor behavior defective,flight defective" FBgn0053853 His2A:CG33853 His2A:CG33853 http://flybase.org/reports/FBgn0053853 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33853, His2A:CG33853" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33853 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-261m9.15, Drer\LOC100332229, Drer\LOC570115, Drer\si:ch73-368j24.15, Drer\si:dkey-261m9.11, Drer\zgc:110434, Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.11, Drer\zgc:114037, Drer\si:dkey-23a13.14, Drer\si:dkey-261m9.7, Drer\h2afy2, Drer\h2afx, Drer\zgc:154164, Drer\zgc:173652, Drer\si:ch73-368j24.14, Drer\si:ch73-36p18.5, Drer\zgc:195633, Drer\si:ch1073-159d7.10, Drer\si:ch211-113a14.16, Drer\si:ch211-113a14.26, Drer\si:dkey-23a13.20, Drer\si:ch73-368j24.13, Drer\LOC100148591, Drer\si:dkey-108k21.19, Drer\si:dkey-261m9.18, Drer\si:ch1073-159d7.11, Drer\si:dkey-108k21.26, Drer\zgc:101846, Drer\si:ch211-113a14.19, Drer\si:dkey-108k21.15, Drer\LOC100334934, Drer\si:ch211-113a14.7, Drer\fbxl6" "Scer\HTA2, Scer\HTA1" "Cele\his-3, Cele\his-19, Cele\his-35, Cele\his-30, Cele\his-65, Cele\his-16, Cele\his-61, Cele\his-33, Cele\his-53, Cele\his-57, Cele\his-51, Cele\his-43, Cele\htas-1, Cele\his-68, Cele\his-7, Cele\his-12, Cele\his-21, Cele\his-47" "Xtro\LOC101732059, Xtro\LOC101734842, Xtro\LOC100497241, Xtro\LOC100487067, Xtro\LOC101731908, Xtro\LOC101733262, Xtro\LOC100496752, Xtro\LOC101730817, Xtro\LOC101734900, Xtro\LOC100492975, Xtro\h2afy, Xtro\LOC101730371, Xtro\LOC100495187, Xtro\LOC100485081, Xtro\LOC100493706, Xtro\LOC101735111, Xtro\LOC101730761, Xtro\LOC101732908, Xtro\LOC101730347, Xtro\LOC100497614, Xtro\LOC100496244, Xtro\h2afj, Xtro\hist1h2ad, Xtro\LOC101733880, Xtro\LOC100494316, Xtro\LOC101731006, Xtro\LOC101731897, Xtro\LOC101731295, Xtro\LOC100492813, Xtro\h2afy2, Xtro\LOC100487632, Xtro\LOC100489065, Xtro\LOC100486008, Xtro\hist1h2aj, Xtro\hist2h2ab, Xtro\hist1h2aa, Xtro\LOC100491383, Xtro\LOC100495988, Xtro\LOC101733986, Xtro\LOC100492873, Xtro\LOC100487588, Xtro\LOC101735276, Xtro\h2afx, Xtro\LOC100488074, Xtro\LOC100495625, Xtro\hist1h2ah, Xtro\LOC100488903, Xtro\LOC100488021, Xtro\LOC100496440, Xtro\LOC101734285, Xtro\hist1h2am, Xtro\LOC100496919, Xtro\LOC100496089, Xtro\LOC101733656, Xtro\LOC100485548, Xtro\LOC101732823, Xtro\LOC100485854" "Mmus\H2afy2, Mmus\Hist1h2an, Mmus\Hist1h2ab, Mmus\Hist1h2aa, Mmus\H2al1j, Mmus\Hist1h2ao, Mmus\Hist2h2aa1, Mmus\Hist1h2ap, Mmus\Hist1h2ac, Mmus\Hist1h2ak, Mmus\Hist1h2af, Mmus\Hist2h2ac, Mmus\Hist1h2ae, Mmus\Hist1h2ad, Mmus\Hist3h2a, Mmus\H2afb3, Mmus\H2afb1, Mmus\Hist1h2ag, Mmus\Hist2h2ab, Mmus\H2al1n, Mmus\H2al2c, Mmus\Hist2h2aa2, Mmus\H2afx, Mmus\H2afb2, Mmus\Hist1h2ai, Mmus\H2al2b, Mmus\Gm14920, Mmus\Hist2h3c1, Mmus\H2afj, Mmus\H2afy, Mmus\Hist1h2ah" "Hsap\H2AFX, Hsap\HIST1H2AD, Hsap\H2AFY, Hsap\HIST1H2AJ, Hsap\HIST1H2AI, Hsap\HIST1H2AM, Hsap\HIST1H2AB, Hsap\H2AFB1, Hsap\HIST1H2AA, Hsap\HIST2H2AB, Hsap\HIST1H2AL, Hsap\H2AFB3, Hsap\HIST1H2AC, Hsap\H2AFJ, Hsap\HIST2H2AA4, Hsap\H2AFB2, Hsap\HIST3H2A, Hsap\HIST1H2AE, Hsap\H2AFY2, Hsap\HIST1H2AG, Hsap\HIST1H2AH, Hsap\HIST1H2AK, Hsap\HIST2H2AC, Hsap\HIST2H2AA3" FBgn0011662 mousse mousse http://flybase.org/reports/FBgn0011662 - gene - - - mousse - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266076 mir-276a mir-276a stem loop http://flybase.org/reports/FBgn0266076 miRNA_gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "dme-mir-276a, mir-276a, miR-276a, MIR-276, 276a, CR43001, CR33584, MiR-276a, miR-276, CR33585, miR-276aS, dme-mir-276, mir-276aS, rosa, dme-miR-276a-3p, dme-miR-276a" - CR43001 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260941 app approximated http://flybase.org/reports/FBgn0260941 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 pattern specification process ; GO:0007389 | inferred from mutant phenotype establishment of body hair or bristle planar orientation ; GO:0048104 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay "app, CG5620, CG17144, CG42318, CR32097, App" "IPR001594:Palmitoyltransferase, DHHC domain" CG42318 11-Aug-17 DroID_v2017_08 "Drer\zdhhc23b, Drer\zgc:77880, Drer\zdhhc3b, Drer\zdhhc21, Drer\zdhhc24, Drer\zdhhc14, Drer\LOC100334198, Drer\zdhhc22, Drer\zdhhc5a, Drer\zdhhc9, Drer\zdhhc7, Drer\zdhhc3a, Drer\zdhhc12b, Drer\zdhhc8b, Drer\zdhhc23a, Drer\zdhhc12a, Drer\zdhhc5b, Drer\zdhhc18b, Drer\zdhhc1, Drer\zdhhc4, Drer\zdhhc18a" "Scer\ERF2, Scer\PFA5, Scer\SWF1" "Cele\dhhc-8, Cele\dhhc-2" "Xtro\zdhhc3, Xtro\zdhhc1, Xtro\zdhhc8, Xtro\zdhhc7, Xtro\zdhhc9, Xtro\zdhhc14, Xtro\zdhhc24, Xtro\zdhhc12, Xtro\zdhhc21, Xtro\dnz1" "Mmus\Zdhhc8, Mmus\Zdhhc4, Mmus\Zdhhc22, Mmus\Zdhhc14, Mmus\Zdhhc24, Mmus\Zdhhc18, Mmus\Zdhhc1, Mmus\Zdhhc21, Mmus\Zdhhc23, Mmus\Zdhhc11, Mmus\Zdhhc19, Mmus\Zdhhc5, Mmus\Zdhhc7, Mmus\Zdhhc9, Mmus\Zdhhc3, Mmus\Zdhhc25, Mmus\Zdhhc12" "Hsap\ZDHHC19, Hsap\ZDHHC12, Hsap\ZDHHC3, Hsap\ZDHHC7, Hsap\ZDHHC4, Hsap\ZDHHC21, Hsap\ZDHHC11, Hsap\ZDHHC9, Hsap\ZDHHC18, Hsap\ZDHHC14, Hsap\ZDHHC23, Hsap\ZDHHC5, Hsap\ZDHHC1, Hsap\ZDHHC22, Hsap\ZDHHC8, Hsap\ZDHHC24" FBgn0061157 l(2)2-L lethal (2) 2-L http://flybase.org/reports/FBgn0061157 gene - - - l(2)2-L - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0016938 smi98B smell impaired 98B http://flybase.org/reports/FBgn0016938 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi98B - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0260110 2L3393 - http://flybase.org/reports/FBgn0260110 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L3393 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0029861 CG3815 - http://flybase.org/reports/FBgn0029861 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 transcription cofactor activity ; GO:0003712 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000371549" Sin3-type complex ; GO:0070822 | inferred from direct assay "PF1, CG3815, Pf1" "IPR000253:Forkhead-associated (FHA) domain, IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR031966:PHD finger protein 12, MRG binding domain" CG3815 11-Aug-17 DroID_v2017_08 "Drer\phf21ab, Drer\phf12a, Drer\aire, Drer\phf12b" Scer\RCO1 "Cele\athp-1, Cele\phf-33" Xtro\phf12 "Mmus\Phf12, Mmus\Aire" "Hsap\AIRE, Hsap\PHF12" FBgn0001563 l(1)19Fc lethal (1) 19Fc http://flybase.org/reports/FBgn0001563 - gene - - - "YT57, l(1)19Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000149 aw-b awry b http://flybase.org/reports/FBgn0000149 - gene - - - "aw[2], aw-b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,reduced" wing FBgn0086491 T:Myr-Src42A Myristoylation sequence of Src42A http://flybase.org/reports/FBgn0086491 engineered_tag - - - "myr, T:Myr-Src42A, T:Myr6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030814 CG4955 - http://flybase.org/reports/FBgn0030814 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.97, CG4955" - CG4955 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19927 K -0.108010329 0.75084093 -0.073309005 0.053746086 0.767701102 1.735888068 FBgn0283457 EC3-12 Enhancer of CCT 3-12 http://flybase.org/reports/FBgn0283457 gene - - - EC3-12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013262 E(var)61 E(var)61 http://flybase.org/reports/FBgn0013262 - gene - - - E(var)61 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0024807 DIP1 DISCO Interacting Protein 1 http://flybase.org/reports/FBgn0024807 - protein_coding_gene pre-miRNA binding ; GO:0070883 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Ubx double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity double-stranded RNA binding ; GO:0003725 | inferred from direct assay defense response to virus ; GO:0051607 | inferred from mutant phenotype cellular response to virus ; GO:0098586 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "UbxBP1, klt, CG17686, dip1a, clot 2020, clot 10495, TO67, TO34, dip1, DIP1" IPR014720:Double-stranded RNA-binding domain CG17686 11-Aug-17 DroID_v2017_08 "Drer\stau1, Drer\stau2" Scer\TAD1 "Cele\adr-1, Cele\stau-1, Cele\D2005.1, Cele\adr-2" - "Mmus\Stau1, Mmus\Adarb1, Mmus\Stau2" "Hsap\STAU1, Hsap\STAU2, Hsap\ADARB2, Hsap\ADARB1" "fertile,female fertile,visible,lethal,decreased cell number,viable" "eye,head capsule,chaeta,ectopic,antenna,arista,wing,haltere,wing vein,wing margin bristle,capitellum" FBgn0030528 CG11095 - http://flybase.org/reports/FBgn0030528 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797" - - CG11095 "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like" CG11095 11-Aug-17 DroID_v2017_08 "Drer\nudt7, Drer\nudt8" Scer\PCD1 "Cele\ndx-8, Cele\ndx-3" "Xtro\nudt8, Xtro\nudt7" "Mmus\Nudt8, Mmus\Nudt7" "Hsap\NUDT7, Hsap\NUDT8" viable DRSC26123 K -0.332566449 0.65490444 0.22704819 0.270405551 1.822249871 0.600996586 FBgn0038186 CG14362 - http://flybase.org/reports/FBgn0038186 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "CG14362, CBP10" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG14362 11-Aug-17 DroID_v2017_08 "Drer\chp2, Drer\tesca, Drer\ppp3r1b, Drer\ppp3r1a, Drer\tescb, Drer\LOC100536377, Drer\chp1" Scer\CNB1 "Cele\chpf-2, Cele\pbo-1" "Xtro\chp1, Xtro\cib1, Xtro\ppp3r1" "Mmus\Tescl, Mmus\Chp2, Mmus\Tesc, Mmus\Cib1, Mmus\Chp1, Mmus\Cib4, Mmus\Ppp3r1, Mmus\Ppp3r2" "Hsap\PPP3R2, Hsap\CIB1, Hsap\PPP3R1, Hsap\CIB4, Hsap\CHP2, Hsap\CHP1, Hsap\TESC" viable FBgn0022280 l(2)IR30 lethal (2) IR30 http://flybase.org/reports/FBgn0022280 - gene - - - l(2)IR30 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052241 CG32241 - http://flybase.org/reports/FBgn0052241 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32241 - CG32241 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0261519 did diminished discs http://flybase.org/reports/FBgn0261519 gene - - - "l(3)ds15, l(3)SG67, l(3)ds-15, l(3)IX-11, l(3)B15, did" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,eye-antennal disc,ventral thoracic disc,haltere disc,genital disc,cell cycle" FBgn0067740 l(1)G0313 lethal (1) G0313 http://flybase.org/reports/FBgn0067740 gene - - - l(1)G0313 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005460 l(1)v463 lethal (1) v463 http://flybase.org/reports/FBgn0005460 - gene - - - "l(1)463, l(1)v463" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030612 CG5599 - http://flybase.org/reports/FBgn0030612 protein_coding_gene dihydrolipoamide branched chain acyltransferase activity ; GO:0004147 | inferred from sequence or structural similarity with UniProtKB:P11182 phagocytosis ; GO:0006909 | inferred from mutant phenotype tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P11182 mitochondrial oxoglutarate dehydrogenase complex ; GO:0009353 | inferred from sequence or structural similarity with UniProtKB:P11182 CG5599 "IPR000089:Biotin/lipoyl attachment, IPR001078:2-oxoacid dehydrogenase acyltransferase, catalytic domain, IPR003016:2-oxo acid dehydrogenase, lipoyl-binding site, IPR004167:E3-binding domain, IPR011053:Single hybrid motif, IPR015761:Lipoamide Acyltransferase" CG5599 11-Aug-17 DroID_v2017_08 Drer\dbt "Scer\PDX1, Scer\LAT1" Cele\dbt-1 Xtro\dbt Mmus\Dbt Hsap\DBT "lethal,recessive,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0040691 CG13915 - http://flybase.org/reports/FBgn0040691 protein_coding_gene - - - CG13915 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039113 CG10217 - http://flybase.org/reports/FBgn0039113 protein_coding_gene molecular_function ; GO:0003674 | no biological data available wound healing ; GO:0042060 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG10217 - CG10217 11-Aug-17 DroID_v2017_08 - - "Cele\C26D10.6, Cele\F35D2.6" - - - "partially lethal - majority die,some die during pupal stage" FBgn0260804 EP3-378 - http://flybase.org/reports/FBgn0260804 gene - - - EP3-378 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041248 Gr23a Gustatory receptor 23a http://flybase.org/reports/FBgn0041248 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr23aB, Gr23aA, Gr23a.b, Gr23a.a, Gr23A1b, Gr23A1a, 23A1b, 23A1a, GR23A.1, 23A1.b, 23A.1a, CG15396, Gr23a, GR23a" IPR013604:7TM chemoreceptor CG15396 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - "viable,fertile,visible" mesothoracic tergum FBgn0037521 CG2993 - http://flybase.org/reports/FBgn0037521 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype - CG2993 "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG2993 11-Aug-17 DroID_v2017_08 "Drer\arrdc2, Drer\si:ch211-130m23.2, Drer\LOC799768, Drer\zgc:110353, Drer\arrdc3a, Drer\arrdc1b, Drer\txnipb, Drer\zgc:110626, Drer\txnipa, Drer\arrdc3b, Drer\arrdc1a" "Scer\ROD1, Scer\RIM8, Scer\LDB19, Scer\ALY1, Scer\ECM21, Scer\ALY2, Scer\ART5, Scer\ROG3, Scer\CSR2" "Cele\arrd-19, Cele\arrd-2, Cele\arrd-9, Cele\arrd-12, Cele\arrd-25, Cele\arrd-13, Cele\arrd-1, Cele\arrd-3, Cele\arrd-23, Cele\arrd-24, Cele\arrd-11, Cele\arrd-27, Cele\arrd-8, Cele\arrd-16, Cele\arrd-5, Cele\arrd-14, Cele\arrd-6, Cele\arrd-7, Cele\arrd-22, Cele\rnh-1.2, Cele\arrd-4, Cele\arrd-18, Cele\arrd-15" "Xtro\arrdc4, Xtro\arrdc3, Xtro\txnip, Xtro\arrdc2" "Mmus\Arrdc5, Mmus\Txnip, Mmus\Arrdc1, Mmus\Arrdc2, Mmus\Arrdc3, Mmus\Arrdc4" "Hsap\TXNIP, Hsap\ARRDC4, Hsap\ARRDC1, Hsap\ARRDC5, Hsap\ARRDC2, Hsap\ARRDC3" lethal FBgn0263843 CR43704 - http://flybase.org/reports/FBgn0263843 non_protein_coding_gene - - - CR43704 - CR43704 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026345 Su(rdgB)116 Su(rdgB)116 http://flybase.org/reports/FBgn0026345 - gene - - - Su(rdgB)116 - - 11-Aug-17 DroID_v2017_08 - - - - - - "retina,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6" FBgn0036605 CG13041 - http://flybase.org/reports/FBgn0036605 protein_coding_gene - - - "BcDNA:RE63063, CG13041" IPR007614:Retinin-like protein CG13041 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034454 CG15120 - http://flybase.org/reports/FBgn0034454 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from sequence or structural similarity with HGNC:19152 negative regulation of cell death ; GO:0060548 | inferred from sequence or structural similarity with HGNC:19152 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:19152 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:19152 CG15120 "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR019399:Parkin co-regulated protein" CG15120 11-Aug-17 DroID_v2017_08 Drer\pacrg - Cele\E04F6.2 "Xtro\pacrg, Xtro\pacrgl" "Mmus\Pacrg, Mmus\Pacrgl" "Hsap\PACRG, Hsap\PACRGL" "viable,fertile" FBgn0267308 CR45744 - http://flybase.org/reports/FBgn0267308 non_protein_coding_gene - - - CR45744 - CR45744 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069428 JJF008 JJF008 http://flybase.org/reports/FBgn0069428 gene - - - JJF008 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0265838 CR44627 - http://flybase.org/reports/FBgn0265838 non_protein_coding_gene - - - "CR44627, lincRNA.352" - CR44627 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053361 5SrRNA:CR33361 5SrRNA:CR33361 http://flybase.org/reports/FBgn0053361 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33361, 5SrRNA:CR33361" - CR33361 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060895 l(3)S044402 lethal (3) S044402 http://flybase.org/reports/FBgn0060895 gene - - - "444/2, 0444/02, l(3)S044402" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035312 CG15820 - http://flybase.org/reports/FBgn0035312 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD08776, CG15820" "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG15820 11-Aug-17 DroID_v2017_08 Drer\serhl - "Cele\abhd-5.1, Cele\W01A11.1" "Xtro\serhl2, Xtro\serhl" Mmus\Serhl Hsap\SERHL2 viable FBgn0016982 snRNA:K2a small nuclear RNA K2a http://flybase.org/reports/FBgn0016982 - snRNA_gene - - - "K2a, snRNA:K2a" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032405 firl firelighter http://flybase.org/reports/FBgn0032405 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype - "CG14946, firl" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG14946 11-Aug-17 DroID_v2017_08 "Drer\dhrs3a, Drer\rdh10a, Drer\dhrs3b, Drer\rdh10b, Drer\si:dkey-221h15.4, Drer\rdh20, Drer\sdr16c5b, Drer\sdr16c5a" "Scer\TDA5, Scer\YDL114W" "Cele\dhs-3, Cele\dhs-29, Cele\dhs-4, Cele\dhs-19" "Xtro\sdr16c5, Xtro\rdh10, Xtro\dhrs3, Xtro\hsd17b11, Xtro\hsd17b13" "Mmus\Sdr16c5, Mmus\Dhrs3, Mmus\Sdr16c6, Mmus\Hsd17b13, Mmus\Rdh10, Mmus\Hsd17b11" "Hsap\SDR16C5, Hsap\DHRS3, Hsap\HSD17B13, Hsap\RDH10, Hsap\HSD17B11" viable FBgn0023033 l(2)46Ej lethal (2) 46Ej http://flybase.org/reports/FBgn0023033 - gene - - - "H, l(2)46Ej" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034414 CG15108 - http://flybase.org/reports/FBgn0034414 protein_coding_gene - - - CG15108 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031698 Ncoa6 Nuclear receptor coactivator 6 http://flybase.org/reports/FBgn0031698 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR020849 histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype positive regulation of hippo signaling ; GO:0035332 | inferred from genetic interaction with sd inferred from genetic interaction with wts inferred from genetic interaction with yki inferred from physical interaction with yki histone H3-K4 methylation ; GO:0051568 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 MLL3/4 complex ; GO:0044666 | inferred from direct assay "CG14023, NcoA6, Ncoa6, dNCOA6, NCOA6" "IPR020849:Small GTPase superfamily, Ras type, IPR015943:WD40/YVTN repeat-like-containing domain" CG14023 11-Aug-17 DroID_v2017_08 Drer\ncoa6 - - Xtro\ncoa6 Mmus\Ncoa6 Hsap\NCOA6 "viable,visible" "chaeta,supernumerary" DRSC23060 K 0.820537438 1.67593614 FBgn0040092 lectin-46Cb lectin-46Cb http://flybase.org/reports/FBgn0040092 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 galactose binding ; GO:0005534 | inferred from sequence or structural similarity carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sperm competition ; GO:0046692 | inferred from direct assay protein localization ; GO:0008104 | inferred from mutant phenotype regulation of female receptivity, post-mating ; GO:0046008 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG1652, AC007330b, AC 007330B, lectin-46Cb, lectin46Cb, Lectin-46Cb" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG1652 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000000937, Drer\illr1, Drer\colec11, Drer\si:dkey-61f9.2, Drer\si:ch211-170d8.5, Drer\selp, Drer\zmp:0000000924, Drer\illr2, Drer\si:ch73-122g19.1, Drer\LOC100331140, Drer\si:ch73-86n18.1, Drer\si:dkey-187i8.2, Drer\si:ch211-283g2.3, Drer\illr3, Drer\LOC101884526, Drer\si:ch73-343l4.2, Drer\illr4, Drer\LOC100007376, Drer\zgc:174904, Drer\si:ch211-232p21.6, Drer\si:ch73-361h17.1, Drer\si:ch211-214k5.3, Drer\si:ch73-111e15.1, Drer\LOC101884413, Drer\si:ch73-343l4.8, Drer\LOC101886537, Drer\si:dkey-61f9.1, Drer\si:ch211-125e6.12, Drer\si:ch211-125e6.13, Drer\si:dkey-26c10.5, Drer\cd209, Drer\si:ch211-133n4.7" - "Cele\clec-185, Cele\clec-160, Cele\clec-184, Cele\clec-31, Cele\clec-149, Cele\clec-26, Cele\clec-202, Cele\clec-7, Cele\clec-4, Cele\clec-38, Cele\C25G4.17, Cele\clec-17, Cele\clec-39, Cele\clec-199, Cele\clec-9, Cele\clec-198" - "Mmus\Asgr1, Mmus\Clec5a, Mmus\Clec4f, Mmus\Clec4a3, Mmus\Cd209c, Mmus\Clec4b1, Mmus\Mgl2, Mmus\Klrc3, Mmus\Clec2h, Mmus\Cd209f, Mmus\Clec4a4, Mmus\Cd209e, Mmus\Cd209b, Mmus\Clec4b2, Mmus\Clec1b, Mmus\Clec4d, Mmus\Clec10a, Mmus\Cd209a, Mmus\Fcer2a, Mmus\Clec4e, Mmus\Colec12, Mmus\Klrc1, Mmus\Klre1, Mmus\Asgr2, Mmus\Cd209g, Mmus\Clec4a2, Mmus\Clec1a, Mmus\Clec2d, Mmus\Cd209d, Mmus\Klrb1f, Mmus\Klrk1, Mmus\Cd69, Mmus\Clec4n, Mmus\Clec4g, Mmus\Cd207, Mmus\Clec4a1, Mmus\Sftpd" "Hsap\CD209, Hsap\CLEC9A, Hsap\CLEC4E, Hsap\CLEC4G, Hsap\CLEC1B, Hsap\CLEC2D, Hsap\CLEC4M, Hsap\CD207, Hsap\COLEC10, Hsap\CLEC4A, Hsap\CLEC10A, Hsap\OLR1, Hsap\ASGR1, Hsap\KLRG2, Hsap\CLEC4F, Hsap\ASGR2, Hsap\CD69, Hsap\CLEC6A, Hsap\CLEC17A, Hsap\CLEC2B, Hsap\CLEC4C, Hsap\KLRG1, Hsap\COLEC12, Hsap\CLEC1A, Hsap\CLEC5A, Hsap\FCER2, Hsap\CLEC4D" "mating rhythm defective,viable" FBgn0267543 CR45883 - http://flybase.org/reports/FBgn0267543 non_protein_coding_gene - - - CR45883 - CR45883 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085685 CG41554 - http://flybase.org/reports/FBgn0085685 protein_coding_gene - - - CG41554 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002292 l(3)80Fc lethal (3) 80Fc http://flybase.org/reports/FBgn0002292 - gene - - - "l6, l(3)Lh6, l(3)80Fc, 80Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024605 olfJ78 olfactory J78 http://flybase.org/reports/FBgn0024605 - gene - - - olfJ78 - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0084046 CG41488 - http://flybase.org/reports/FBgn0084046 protein_coding_gene - - - CG41488 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043792 CG30427 - http://flybase.org/reports/FBgn0043792 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype - "CG2858, BEST:LD36843, CG18680, CG30427" "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG30427 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97m3.1, Drer\far1" - Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR2, Hsap\FAR1" "long lived,viable" FBgn0086321 JV166 - http://flybase.org/reports/FBgn0086321 gene - - - JV166 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0041093 stau::Mdoa\stau stau::Mdoa\stau http://flybase.org/reports/FBgn0041093 engineered_fusion_gene - - - stau::Mdoa\stau - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259874 Su(Ste):CR42443 Su(Ste):CR42443 http://flybase.org/reports/FBgn0259874 non_protein_coding_gene - - - "Su(Ste):CR42443, CR42443" - CR42443 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035948 CG5644 - http://flybase.org/reports/FBgn0035948 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "anon-EST:Posey104, CG5644" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG5644 11-Aug-17 DroID_v2017_08 - - "Cele\H06H21.8, Cele\dhs-27, Cele\C29F7.1, Cele\nhr-246, Cele\C29F7.2" - - - viable FBgn0003999 wa warty http://flybase.org/reports/FBgn0003999 - gene - - - wa - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male sterile,partially,female sterile,dominant,recessive" "eye,ommatidium,wing" FBgn0263579 mir-4947 mir-4947 stem loop http://flybase.org/reports/FBgn0263579 miRNA_gene - - - "mir-4947, dme-mir-4947, CR43564" - CR43564 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031988 CG8668 - http://flybase.org/reports/FBgn0031988 protein_coding_gene galactosyltransferase activity ; GO:0008378 | inferred from electronic annotation with InterPro:IPR002659 protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR002659 synaptic target recognition ; GO:0008039 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "CG8668, dbeta3GnT, GalT4" "IPR002659:Glycosyl transferase, family 31" CG8668 11-Aug-17 DroID_v2017_08 "Drer\b3gnt5b, Drer\LOC565422, Drer\si:ch73-195i19.3, Drer\b3gnt2l, Drer\si:dkey-175m17.6, Drer\b3gnt9, Drer\b3gnt2a, Drer\b3gnt7l, Drer\LOC100535930, Drer\b3gnt5a, Drer\b3gnt2b, Drer\si:dkey-160o24.3, Drer\b3gnt7, Drer\si:ch211-126g16.11, Drer\b3galnt2, Drer\b3galt2, Drer\b3galt1a, Drer\LOC100333524, Drer\b3galt4, Drer\zgc:194551, Drer\b3galt1b, Drer\zgc:194330, Drer\zgc:86586, Drer\b3gnt3" - "Cele\F14B6.6, Cele\bre-5, Cele\T09E11.10, Cele\B0024.15, Cele\F14B6.4, Cele\bus-2, Cele\C47F8.3, Cele\F48F7.3, Cele\C47F8.5, Cele\T09F5.1, Cele\T15D6.5, Cele\bre-2, Cele\E03H4.11" "Xtro\b3galt2, Xtro\LOC100487553, Xtro\LOC100494986, Xtro\b3gnt4, Xtro\LOC100489267, Xtro\LOC100493833, Xtro\b3gnt3, Xtro\b3gnt5, Xtro\b3galnt2, Xtro\b3gnt2, Xtro\b3galt1, Xtro\b3galt4, Xtro\b3gnt6, Xtro\b3gnt3, Xtro\LOC100494668" "Mmus\B3galt5, Mmus\B3gnt7, Mmus\B3gnt5, Mmus\B3gnt4, Mmus\B3gnt3, Mmus\B3galnt1, Mmus\B3galnt2, Mmus\B3gnt9, Mmus\B3galt4, Mmus\B3gnt6, Mmus\B3gnt2, Mmus\B3galt1, Mmus\B3gnt8, Mmus\B3galt2" "Hsap\B3GNT7, Hsap\B3GNT9, Hsap\B3GALNT1, Hsap\B3GNT3, Hsap\B3GALT4, Hsap\B3GNT5, Hsap\B3GNT2, Hsap\B3GALT5, Hsap\B3GALT2, Hsap\B3GNT6, Hsap\B3GALT1, Hsap\B3GNT8, Hsap\B3GNT4, Hsap\B3GALNT2" viable FBgn0058124 CG40124 - http://flybase.org/reports/FBgn0058124 protein_coding_gene - - - CG40124 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011085 l(1)Q43 lethal (1) Q43 http://flybase.org/reports/FBgn0011085 FBgn0010210 gene - - - l(1)Q43 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020372 TM4SF Transmembrane 4 superfamily http://flybase.org/reports/FBgn0020372 - protein_coding_gene - cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "CG11303, Dm.Tsp60A, TM4SF" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG11303 11-Aug-17 DroID_v2017_08 "Drer\tspan7, Drer\cd82a, Drer\zgc:171713, Drer\tspan7b, Drer\cd82b, Drer\cd63" - Cele\tsp-9 "Xtro\cd63, Xtro\tspan6" "Mmus\Tspan6, Mmus\Cd82, Mmus\Tspan7, Mmus\Cd37" "Hsap\TSPAN6, Hsap\TSPAN19, Hsap\TSPAN7, Hsap\CD82, Hsap\CD37" " pupal stage , embryonic stage , adult stage " viable FBgn0002178 l(3)62Bb lethal (3) 62Bb http://flybase.org/reports/FBgn0002178 - gene - - - "dre9, l(3)dre9, l(3)62Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0038143 CG9813 - http://flybase.org/reports/FBgn0038143 protein_coding_gene - - - "CG9813, ORE-7" - CG9813 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary" FBgn0051259 CG31259 - http://flybase.org/reports/FBgn0051259 protein_coding_gene molecular_function ; GO:0003674 | no biological data available peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with RGD:1309948 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with RGD:1309948 peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000279123 "CG11740, CG31259" "IPR026749:Transmembrane protein 135, IPR031926:Transmembrane protein 135, N-terminal domain" CG31259 11-Aug-17 DroID_v2017_08 Drer\tmem135 - Cele\tmem-135 Xtro\tmem135 Mmus\Tmem135 Hsap\TMEM135 viable FBgn0004191 snRNA:U2:34ABa small nuclear RNA U2 at 34ABa http://flybase.org/reports/FBgn0004191 "FBgn0003919, FBgn0003921" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay "U2, dU2, U2 snRNA, U2-34ABa, U2-131A, D.U2-1, 131A, U2 131A, Dm U2-131A, K6, snRNA:U2, snRNA-U2-131A, U2snRNA34ABa, CR31850, U2snRNA, snRNA:U2:34ABa, U2:34ABa, 34B U2, chr2L:13211901..13212079" - CR31850 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0024875 l(2)k00301 lethal (2) k00301 http://flybase.org/reports/FBgn0024875 - gene - - - l(2)k00301 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000892 fs(1)M91 female sterile (1) M91 http://flybase.org/reports/FBgn0000892 - gene - - - fs(1)M91 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0060743 l(3)S066208 lethal (3) S066208 http://flybase.org/reports/FBgn0060743 gene - - - "0662/08, l(3)S066208" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265631 CG44438 - http://flybase.org/reports/FBgn0265631 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44438, lincRNA.249" - CG44438 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030156 CG15247 - http://flybase.org/reports/FBgn0030156 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15247 IPR032064:Protein of unknown function DUF4805 CG15247 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0062411 Ctr1C Copper transporter 1C http://flybase.org/reports/FBgn0062411 protein_coding_gene copper ion transmembrane transporter activity ; GO:0005375 | inferred from direct assay copper ion transmembrane transport ; GO:0035434 | inferred from electronic annotation with InterPro:IPR007274 copper ion transport ; GO:0006825 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype copper ion import ; GO:0015677 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007274 plasma membrane ; GO:0005886 | inferred from direct assay "CG15551, BcDNA:AT31946, FBgn0039813, Ctr1C" IPR007274:Ctr copper transporter CG15551 11-Aug-17 DroID_v2017_08 "Drer\slc31a2, Drer\slc31a1" "Scer\CTR3, Scer\CTR1, Scer\CTR2" "Cele\Y58A7A.1, Cele\F27C1.2, Cele\F58G6.9, Cele\F31E8.4, Cele\F58G6.3, Cele\K12C11.7, Cele\K12C11.3, Cele\F58G6.7, Cele\K12C11.6, Cele\F01G12.1" "Xtro\slc31a2, Xtro\slc31a1" "Mmus\Slc31a1, Mmus\Slc31a2" "Hsap\SLC31A1, Hsap\SLC31A2" "viable,lethal - all die during larval stage,heat sensitive,some die during second instar larval stage,some die during third instar larval stage,visible" "wing,eye" FBgn0064116 CG33713 - http://flybase.org/reports/FBgn0064116 protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 - - "cg1704, CG33071, CG1704, CG33071-ORFB, CG33713, Dromel_CG33713_FBtr0091704_mORF, CG33071ORFB" "IPR000582:Acyl-CoA-binding protein, ACBP, IPR002110:Ankyrin repeat, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR020683:Ankyrin repeat-containing domain" CG33713 11-Aug-17 DroID_v2017_08 "Drer\zgc:92030, Drer\dbi, Drer\mettl23, Drer\LOC103909942, Drer\acbd7, Drer\acbd4, Drer\acbd5b, Drer\acbd6" Scer\ACB1 "Cele\acbp-4, Cele\maa-1, Cele\acbp-3, Cele\acbp-5, Cele\acbp-6" "Xtro\eci2, Xtro\mettl23, Xtro\acbd5, Xtro\acbd6, Xtro\acbd7" "Mmus\Mettl23, Mmus\Dbil5, Mmus\Acbd6, Mmus\Eci2, Mmus\Dbi, Mmus\Acbd4, Mmus\Acbd7, Mmus\Acbd5" "Hsap\ACBD6, Hsap\ACBD5, Hsap\ACBD7, Hsap\DBI, Hsap\ACBD4, Hsap\METTL23, Hsap\ECI2" "feeding behavior defective,smell perception defective" FBgn0267165 CR45605 - http://flybase.org/reports/FBgn0267165 non_protein_coding_gene - - - CR45605 - CR45605 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024329 Mekk1 Mekk1 http://flybase.org/reports/FBgn0024329 FBgn0038648 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 mitogen-activated protein kinase kinase binding ; GO:0031434 | inferred from physical interaction with lic MAP kinase kinase kinase activity ; GO:0004709 | inferred from direct assay receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement" engulfment of apoptotic cell ; GO:0043652 | inferred from mutant phenotype intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ; GO:0070059 | inferred from genetic interaction with ninaE cellular response to arsenic-containing substance ; GO:0071243 | inferred from mutant phenotype positive regulation of protein phosphorylation ; GO:0001934 | inferred from genetic interaction with gig cellular response to heat ; GO:0034605 | inferred from mutant phenotype negative regulation of heterochromatin assembly ; GO:0031452 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from biological aspect of ancestor with PANTHER:PTN001220664 cellular response to cadmium ion ; GO:0071276 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype cellular response to heat ; GO:0034605 | inferred from direct assay cellular hyperosmotic salinity response ; GO:0071475 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement MAPK cascade ; GO:0000165 | inferred from direct assay mucosal immune response ; GO:0002385 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype inferred from genetic interaction with gig cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6856 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 "Mekk1/4, D-MEKK1, D-Mekk1, dMEKK4, dMEKK, mekk1b, mekk1a, MEKK4, MEKK, DmMEKK1, mekk1, CG7717, Mekk1, dMEKK1, MEKK1, dMekk1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG7717 11-Aug-17 DroID_v2017_08 "Drer\map3k4, Drer\map3k5" "Scer\STE11, Scer\SSK2, Scer\SSK22, Scer\BCK1" "Cele\mtk-1, Cele\R02C2.6" Xtro\map3k4 "Mmus\Map3k5, Mmus\Map3k4" "Hsap\MAP3K4, Hsap\MAP3K5" "viable,fertile,stress response defective,chemical sensitive,recessive,osmotic stress response defective,heat stress response defective,lethal,conditional,enhancer of variegation,melanotic mass phenotype,nutrition conditional,chemical resistant,visible,cell death defective,immune response defective" "embryonic/larval hindgut,posterior,nutrition conditional,wing,egg chamber,follicle cell" FBgn0028010 l(3)S112110 lethal (3) S112110 http://flybase.org/reports/FBgn0028010 gene - - - "1121/10, l(3)S112110" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267514 5.8SrRNA-Psi:CR45854 5.8S ribosomal RNA pseudogene:CR45854 http://flybase.org/reports/FBgn0267514 pseudogene_attribute - - - "5.8SrRNA-Psi:CR45854, CR45854" - CR45854 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065634 l(2)SH0771 lethal (2) SH0771 http://flybase.org/reports/FBgn0065634 gene - - - l(2)SH0771 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067645 soft-boiled soft boiled http://flybase.org/reports/FBgn0067645 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available soft-boiled - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" "oocyte,germline clone,nurse cell,ectopic" FBgn0010893 l(3)06497 lethal (3) 06497 http://flybase.org/reports/FBgn0010893 - gene - - - l(3)06497 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030858 IntS2 Integrator 2 http://flybase.org/reports/FBgn0030858 protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA 3'-end processing ; GO:0034472 | inferred from direct assay snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:29241 neurogenesis ; GO:0022008 | inferred from mutant phenotype integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:29241 "IntS2, Int2, CG8211" "IPR029321:Integrator complex subunit 2, IPR026236:Integrator complex subunit 2, metazoa" CG8211 11-Aug-17 DroID_v2017_08 "Drer\ints2, Drer\LOC103911748" - Cele\ZC376.6 Xtro\ints2 Mmus\Ints2 Hsap\INTS2 "lethal,neuroanatomy defective,partially lethal - majority die" "embryonic/larval neuroblast,ganglion mother cell" DRSC20094 IK 0.810254832 -1.904156837 0.430740489 -0.862641018 -1.617064494 -0.557615482 FBgn0041160 comm2 comm2 http://flybase.org/reports/FBgn0041160 protein_coding_gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from electronic annotation with InterPro:IPR031878 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7554, comm2" IPR031878:Commissureless CG7554 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052188 CG32188 - http://flybase.org/reports/FBgn0052188 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32188 - CG32188 11-Aug-17 DroID_v2017_08 - - - - - - DRSC09510 I 0.70342502 1.648947926 0.102321425 0.250448873 -0.564613534 -0.168859109 FBgn0260597 2L3073 - http://flybase.org/reports/FBgn0260597 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3073 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0037591 Or85c Odorant receptor 85c http://flybase.org/reports/FBgn0037591 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "85c, DOR78, 85A.3, CG17911, Or85c" "IPR004117:Olfactory receptor, insect" CG17911 11-Aug-17 DroID_v2017_08 - - Cele\T11F8.1 - - - "smell perception defective,viable" FBgn0010370 meso17A mesoderm specific 17A http://flybase.org/reports/FBgn0010370 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "Dmeso17A, meso17A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038291 CG3984 - http://flybase.org/reports/FBgn0038291 protein_coding_gene - - - CG3984 - CG3984 11-Aug-17 DroID_v2017_08 - - - - Mmus\Acrv1 Hsap\ACRV1 viable FBgn0267429 CG45782 - http://flybase.org/reports/FBgn0267429 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG41343, CG41087, CG45782, CG40467, GH10292, Slc45-2" IPR020846:Major facilitator superfamily domain CG45782 11-Aug-17 DroID_v2017_08 "Drer\slc45a2, Drer\slc45a3, Drer\LOC100329687, Drer\slc45a4, Drer\zgc:77158, Drer\slc45a1" - - "Xtro\slc45a4, Xtro\slc45a1, Xtro\slc45a2, Xtro\slc45a3" "Mmus\Slc45a2, Mmus\Slc45a3, Mmus\Slc45a1, Mmus\Slc45a4" "Hsap\SLC45A4, Hsap\SLC45A2, Hsap\SLC45A1, Hsap\SLC45A3" FBgn0032709 CG15167 - http://flybase.org/reports/FBgn0032709 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG15167 - CG15167 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015956 l(1)6Ef lethal (1) 6Ef http://flybase.org/reports/FBgn0015956 - gene - - - "fs/l, l(1)6Ef" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060788 l(3)S059416 lethal (3) S059416 http://flybase.org/reports/FBgn0060788 gene - - - "0594/16, l(3)S059416" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0058137 CG40137 - http://flybase.org/reports/FBgn0058137 protein_coding_gene - - - CG40137 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005555 l(3)85Fh lethal (3) 85Fh http://flybase.org/reports/FBgn0005555 - gene - - - l(3)85Fh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065788 l(2)SH0432 lethal (2) SH0432 http://flybase.org/reports/FBgn0065788 gene - - - "l(2)SH0432, l(2)SH2 0432" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067304 D12.A D12.A http://flybase.org/reports/FBgn0067304 gene - - - "D12, D12.A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,viable" pigment cell FBgn0259113 DNApol-alpha180 DNA polymerase alpha 180kD http://flybase.org/reports/FBgn0259113 protein_coding_gene "3'-5' exonuclease activity ; GO:0008408 | inferred from electronic annotation with InterPro:IPR006133 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006134 nucleoside binding ; GO:0001882 | inferred from electronic annotation with InterPro:IPR015088 nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR006134, InterPro:IPR006172, InterPro:IPR017964 DNA-directed DNA polymerase activity ; GO:0003887 | inferred from direct assay DNA-directed DNA polymerase activity ; GO:0003887 | non-traceable author statement" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR029702 DNA replication ; GO:0006260 | inferred from direct assay leading strand elongation ; GO:0006272 | inferred from biological aspect of ancestor with PANTHER:PTN000035348 double-strand break repair via nonhomologous end joining ; GO:0006303 | inferred from biological aspect of ancestor with PANTHER:PTN000035348 neurogenesis ; GO:0022008 | inferred from mutant phenotype lagging strand elongation ; GO:0006273 | inferred from biological aspect of ancestor with PANTHER:PTN000035348 alpha DNA polymerase:primase complex ; GO:0005658 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG6349, DNApol-alpha180, E(mus304), Dmpol alpha, pol alpha, DNA polalpha, DmPolalpha, AAB24152, polalphap180, POLA, polalpha, Polalpha, DNApol-alpha, DNApola, DNApolalpha, 183 kDa pol alpha, Pol, DNA-Polalpha, DNA Pol-alpha180, Pol alpha, DNApolalpha180, DNApol, DNA polymerase alpha 180 kD, POlalpha 180kDa, dpolalphap180" "IPR017964:DNA-directed DNA polymerase, family B, conserved site, IPR006133:DNA-directed DNA polymerase, family B, exonuclease domain, IPR006134:DNA-directed DNA polymerase, family B, multifunctional domain, IPR006172:DNA-directed DNA polymerase, family B, IPR012337:Ribonuclease H-like domain, IPR015088:Zinc finger, DNA-directed DNA polymerase, family B, alpha, IPR024647:DNA polymerase alpha catalytic subunit, N-terminal domain, IPR029702:DNA polymerase alpha catalytic subunit, IPR023211:DNA polymerase, palm domain" CG6349 11-Aug-17 DroID_v2017_08 Drer\pola1 Scer\POL1 Cele\Y47D3A.29 Xtro\pola1 Mmus\Pola1 Hsap\POLA1 " oogenesis stage && adult stage | female , embryonic stage | early " ovary

" larval stage | first instar , adult stage && oogenesis stage , pupal stage | early , embryonic stage | early " " nurse cell

, follicle cell

" DRSC27879 K -0.631856437 1.014294518 -0.258241262 -0.415402757 1.689109282 0.901302761 FBgn0266029 CR44794 - http://flybase.org/reports/FBgn0266029 non_protein_coding_gene - - - CR44794 - CR44794 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083123 Uhg5 Uhg5 http://flybase.org/reports/FBgn0083123 non_protein_coding_gene - - - "Uhg5, dUhg5, CR42452" - CR42452 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038811 CG4159 - http://flybase.org/reports/FBgn0038811 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001406, InterPro:IPR020094, InterPro:IPR020095, InterPro:IPR020097, InterPro:IPR020103 pseudouridine synthase activity ; GO:0009982 | inferred from biological aspect of ancestor with PANTHER:PTN000124732" mRNA pseudouridine synthesis ; GO:1990481 | inferred from biological aspect of ancestor with PANTHER:PTN000124736 tRNA pseudouridine synthesis ; GO:0031119 | inferred from biological aspect of ancestor with PANTHER:PTN000124732 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000124736 CG4159 "IPR001406:Pseudouridine synthase I, TruA, IPR020095:Pseudouridine synthase I, TruA, C-terminal, IPR020097:Pseudouridine synthase I, TruA, alpha/beta domain, IPR020103:Pseudouridine synthase, catalytic domain" CG4159 11-Aug-17 DroID_v2017_08 Drer\pus1 "Scer\PUS2, Scer\PUS1" Cele\pus-1 Xtro\pus1 Mmus\Pus1 Hsap\PUS1 viable FBgn0058163 CG40163 - http://flybase.org/reports/FBgn0058163 protein_coding_gene - - - CG40163 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032433 Oatp33Ea Organic anion transporting polypeptide 33Ea http://flybase.org/reports/FBgn0032433 protein_coding_gene active transmembrane transporter activity ; GO:0022804 | inferred from sequence or structural similarity with Oatp58Db transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with Oatp58Db organic substance transport ; GO:0071702 | inferred from sequence or structural similarity with Oatp58Db intracellular organelle ; GO:0043229 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Oatp58Db "oatp 33Ea, CG5427, Oatp33Ea" "IPR020846:Major facilitator superfamily domain, IPR004156:Organic anion transporter polypeptide OATP, IPR002350:Kazal domain" CG5427 11-Aug-17 DroID_v2017_08 "Drer\LOC100334356, Drer\slco1f3, Drer\slco3a1, Drer\LOC101883455, Drer\LOC100536648, Drer\LOC570448, Drer\slco1f2, Drer\slco1c1, Drer\slco2a1, Drer\slco5a1, Drer\slco1f4, Drer\slco1d1, Drer\slco1f1, Drer\slco2b1, Drer\slco4a1" - "Cele\F53B1.8, Cele\F47E1.4, Cele\Y32F6B.1, Cele\K02G10.5, Cele\F21G4.1, Cele\Y70G10A.3, Cele\F47E1.2" "Xtro\slco5a1, Xtro\slco4a1, Xtro\slco4c1, Xtro\slco1b3, Xtro\slco3a1, Xtro\slco2a1" "Mmus\Slco1a4, Mmus\Slco4c1, Mmus\Slco6d1, Mmus\Slco1a5, Mmus\Slco2b1, Mmus\Slco3a1, Mmus\Gm5724, Mmus\Slco1a6, Mmus\Slco2a1, Mmus\Slco1b2, Mmus\Slco5a1, Mmus\Slco6c1, Mmus\Gm6614, Mmus\Slco1a1, Mmus\Slco1c1, Mmus\Slco4a1" "Hsap\SLCO4C1, Hsap\SLCO4A1, Hsap\SLCO1A2, Hsap\SLCO5A1, Hsap\SLCO3A1, Hsap\SLCO2B1, Hsap\SLCO2A1, Hsap\SLCO1B1, Hsap\SLCO1B3, Hsap\SLCO1C1, Hsap\SLCO1B7, Hsap\SLCO6A1" lethal FBgn0037749 CG9471 - http://flybase.org/reports/FBgn0037749 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern - "BVR, CG9471" IPR016040:NAD(P)-binding domain CG9471 11-Aug-17 DroID_v2017_08 "Drer\zgc:113340, Drer\blvrb" Scer\YMR090W - Xtro\blvrb Mmus\Blvrb Hsap\BLVRB viable FBgn0259425 C18 - http://flybase.org/reports/FBgn0259425 gene - - - C18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing hair FBgn0259372 EP-708 - http://flybase.org/reports/FBgn0259372 gene - - - EP-708 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0033186 CG1602 - http://flybase.org/reports/FBgn0033186 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR027775 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR027775" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR027775 CG1602 "IPR006578:MADF domain, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027775:C2H2- zinc finger protein family subset" CG1602 11-Aug-17 DroID_v2017_08 - - "Cele\mnm-2, Cele\fezf-1, Cele\eor-1" - "Mmus\Zfp980, Mmus\Zfp995, Mmus\Gm13212" Hsap\ZNF711 "viable,fertile" FBgn0011618 l(1)K48h-1-2 lethal (1) K48h-1-2 http://flybase.org/reports/FBgn0011618 - gene - - - l(1)K48h-1-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000190 Bkd Blackoid http://flybase.org/reports/FBgn0000190 - gene - - - Bkd - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semidominant,body color defective,dominant" FBgn0266460 Dg::shg - http://flybase.org/reports/FBgn0266460 engineered_fusion_gene - - - Dg::shg - - 11-Aug-17 DroID_v2017_08 - - - - - - follicle cell FBgn0267910 MRE16 mRNA-like ncRNA in embryogenesis 16 http://flybase.org/reports/FBgn0267910 non_protein_coding_gene - - - "CR34335, MRE16, CG34335" - CR34335 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039875 sip3 septin interacting protein 3 http://flybase.org/reports/FBgn0039875 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000967687 ubiquitin-specific protease binding ; GO:1990381 | inferred from biological aspect of ancestor with PANTHER:PTN000967687 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000005373 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model p53 binding ; GO:0002039 | inferred from physical interaction with p53 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000967687 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q2XVY7 protein ubiquitination ; GO:0016567 | inferred from direct assay endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from genetic interaction with ninaE protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from sequence or structural similarity with UniProtKB:Q86TM6 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from sequence or structural similarity with SGD:S000005373 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000967687 endoplasmic reticulum quality control compartment ; GO:0044322 | inferred from biological aspect of ancestor with PANTHER:PTN000967687 Hrd1p ubiquitin ligase complex ; GO:0000836 | inferred from biological aspect of ancestor with PANTHER:PTN000967687 integral component of membrane ; GO:0016021 | inferred from sequence model endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q86TM6 Derlin-1 retrotranslocation complex ; GO:0036513 | inferred from biological aspect of ancestor with PANTHER:PTN000967687 "CG1937, sip3, Hrd1, hrd1, dSyno, HRD1, Sip3" "IPR001841:Zinc finger, RING-type, IPR032832:E3 ubiquitin-protein ligase synoviolin/Hrd1, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1937 11-Aug-17 DroID_v2017_08 "Drer\rnf139, Drer\rnf145a, Drer\syvn1, Drer\chfr, Drer\rnf145b, Drer\amfr, Drer\zmp:0000000662, Drer\rnf126" "Scer\SAN1, Scer\HRD1" "Cele\sel-11, Cele\C01G6.4" "Xtro\rnft2, Xtro\LOC100127651, Xtro\syvn1, Xtro\amfr, Xtro\rnf145, Xtro\rnf139, Xtro\chfr" "Mmus\Chfr, Mmus\Dzip3, Mmus\Syvn1, Mmus\Rnf145, Mmus\Rnf149, Mmus\Amfr, Mmus\Rnft2, Mmus\Rnf139" "Hsap\AMFR, Hsap\RNFT2, Hsap\CHFR, Hsap\RNF145, Hsap\RNF139, Hsap\RNFT1, Hsap\SYVN1, Hsap\DZIP3" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002681 mat(2)syn-I maternal effect syncytial blastoderm arrest I http://flybase.org/reports/FBgn0002681 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)synSE10, mat(2)syn-I" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0002955 nofK no object fixation K http://flybase.org/reports/FBgn0002955 - gene - - - nofK - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,visual behavior defective" "optic lobe,rhabdomere | adult stage,pigment cell" FBgn0266849 CR45310 - http://flybase.org/reports/FBgn0266849 non_protein_coding_gene - - - CR45310 - CR45310 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014303 l(3)h2 lethal (3) h2 http://flybase.org/reports/FBgn0014303 - gene - - - l(3)h2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063377 snoRNA:Me28S-A1666a - http://flybase.org/reports/FBgn0063377 snoRNA_gene - - - "U76snoRNA, CR32889, snoRNA:Me28S-A1666a, Me28S-A1666a(U76), snoRNA:U76:54Ea" - CR32889 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000331 Crimp Crimp http://flybase.org/reports/FBgn0000331 - gene - - - "Cm, Crimp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" wing FBgn0061105 l(3)S008206b lethal (3) S008206b http://flybase.org/reports/FBgn0061105 gene - - - "0082/06, l(3)S008206b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0260809 EP3-1729 - http://flybase.org/reports/FBgn0260809 gene - - - EP3-1729 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263247 CG43390 - http://flybase.org/reports/FBgn0263247 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43390 - CG43390 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266773 CR45238 - http://flybase.org/reports/FBgn0266773 non_protein_coding_gene - - - CR45238 - CR45238 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265553 11.158 - http://flybase.org/reports/FBgn0265553 gene - - - 11.158 - - 11-Aug-17 DroID_v2017_08 - - - - - - learning defective FBgn0015625 CycB3 Cyclin B3 http://flybase.org/reports/FBgn0015625 "FBgn0024564, FBgn0062026" protein_coding_gene protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR015452 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P23572 "regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | inferred from electronic annotation with InterPro:IPR015452 regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from electronic annotation with InterPro:IPR015452 cytokinesis ; GO:0000910 | inferred from direct assay regulation of chromatin binding ; GO:0035561 | inferred from genetic interaction with Orc2 syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from genetic interaction with CycA, CycB mitotic cytokinesis ; GO:0000281 | inferred from direct assay mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "cycB3, l(3)L6540, CG5814, anon-WO0118547.414, CycB3, Cyc B3" "IPR004367:Cyclin, C-terminal domain, IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like, IPR015452:Cyclin B3, G2/mitotic-specific" CG5814 11-Aug-17 DroID_v2017_08 "Drer\ccnb1l, Drer\ccng2, Drer\ccnb2, Drer\ccnb3, Drer\ccni, Drer\si:ch211-132b12.8, Drer\ccni2, Drer\ccng1, Drer\ccnb1" "Scer\CLB2, Scer\CLB3, Scer\CLB5, Scer\CLB4, Scer\CLN2, Scer\CLN1, Scer\CLB6, Scer\CLB1, Scer\CLN3" "Cele\cyb-1, Cele\T12C9.7, Cele\cyb-2.2, Cele\cyb-3, Cele\cyb-2.1" "Xtro\ccng2, Xtro\ccnb3, Xtro\ccni2, Xtro\LOC100487861, Xtro\ccno, Xtro\ccnb1, Xtro\ccng1, Xtro\ccni, Xtro\ccnb1.2, Xtro\ccnb2" "Mmus\Ccni, Mmus\Ccng2, Mmus\Ccnb3, Mmus\Ccno, Mmus\Ccnb1, Mmus\Ccng1, Mmus\Ccnb2" "Hsap\CCNB3, Hsap\CCNI2, Hsap\CCNB2, Hsap\CCNO, Hsap\CCNB1, Hsap\FAM58A, Hsap\CCNI, Hsap\CCNG1, Hsap\CNTD2, Hsap\CCNG2" " embryonic stage | early , embryonic stage , adult stage | female " neuroblast

"lethal,viable,fertile,female sterile,recessive,cytokinesis defective,mitotic cell cycle defective,wild-type" "cell cycle,midbody,anaphase & condensed nuclear chromosome,meiosis I,mitotic cell cycleprd.RG1,mitotic anaphaseprd.RG1" DRSC16618 K 0.198747569 -0.279172755 0.40332787 0.996520882 -1.644900258 -0.490081589 FBgn0030928 CG15044 - http://flybase.org/reports/FBgn0030928 protein_coding_gene - - - "BcDNA:RE30049, CG15044" IPR031734:Transcription activator MBF2 CG15044 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260767 CG42565 - http://flybase.org/reports/FBgn0260767 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13512, CG42565" IPR006629:LPS-induced tumour necrosis factor alpha factor CG42565 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-75b4.8, Drer\si:ch211-202h22.9, Drer\si:ch211-157c3.4, Drer\si:ch211-202h22.7, Drer\si:ch211-202h22.8, Drer\litaf, Drer\cdip1" - "Cele\Y40H7A.11, Cele\Y37D8A.26, Cele\Y37D8A.8, Cele\Y37D8A.6, Cele\Y87G2A.19, Cele\B0348.1, Cele\F16F9.1, Cele\Y87G2A.18, Cele\F36G3.3, Cele\B0348.2, Cele\C08E8.1, Cele\Y22D7AL.15" Xtro\litaf "Mmus\Cdip1, Mmus\Litaf" "Hsap\CDIP1, Hsap\LITAF" viable FBgn0005485 l(1)ts1480 lethal (1) ts1480 http://flybase.org/reports/FBgn0005485 - gene - - - l(1)ts1480 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0058415 CG40415 - http://flybase.org/reports/FBgn0058415 protein_coding_gene - - - CG40415 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263946 BG00719 - http://flybase.org/reports/FBgn0263946 gene - - - BG00719 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,short lived,female limited" FBgn0028254 l(3)82Cb lethal (3) 82Cb http://flybase.org/reports/FBgn0028254 gene - - - l(3)82Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061168 l(1)17Cc lethal (1) 17Cc http://flybase.org/reports/FBgn0061168 gene - - - l(1)17Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002214 l(3)67BDl lethal (3) 67BDl http://flybase.org/reports/FBgn0002214 - gene - - - l(3)67BDl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0265047 FDY flagrante delicto Y http://flybase.org/reports/FBgn0265047 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "FDY, CG41503, CR41503, fdy" IPR006861:Hyaluronan/mRNA-binding protein CG41503 11-Aug-17 DroID_v2017_08 "Drer\zgc:103482, Drer\serbp1b, Drer\serbp1a" "Scer\STF2, Scer\TMA10" Cele\vig-1 "Xtro\habp4, Xtro\serbp1" "Mmus\Serbp1, Mmus\Habp4" "Hsap\SERBP1, Hsap\HABP4" FBgn0085260 CG34231 - http://flybase.org/reports/FBgn0085260 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 - - CG34231 IPR000504:RNA recognition motif domain CG34231 11-Aug-17 DroID_v2017_08 Drer\rbm48 - - Xtro\rbm48 Mmus\Rbm48 Hsap\RBM48 FBgn0266030 CR44795 - http://flybase.org/reports/FBgn0266030 non_protein_coding_gene - - - CR44795 - CR44795 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263830 CG40486 - http://flybase.org/reports/FBgn0263830 protein_coding_gene - - - "CG40486, CG12466, FOHSDR" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG40486 11-Aug-17 DroID_v2017_08 "Drer\zgc:153724, Drer\dhrs11a, Drer\dhrs11b, Drer\zgc:92630" Scer\YMR226C "Cele\C30G12.2, Cele\F20G2.2, Cele\H04M03.3" Xtro\dhrs11 "Mmus\Dhrs11, Mmus\Cbr3" "Hsap\CBR3, Hsap\DHRS11" DRSC20619 IK -0.623051406 -2.013643838 -0.38015867 -0.755220586 -0.355206457 1.750045729 FBgn0264788 CR44018 - http://flybase.org/reports/FBgn0264788 non_protein_coding_gene - - - "CR44018, lincRNA.741, lincRNA.742" - CR44018 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043378 EP1121a EP1121a http://flybase.org/reports/FBgn0043378 gene - - - EP1121a - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025512 fs(3)82EFd fs(3)82EFd http://flybase.org/reports/FBgn0025512 - gene - - - fs(3)82EFd - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0030348 CG10352 - http://flybase.org/reports/FBgn0030348 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with HGNC:30259 dephosphorylation ; GO:0016311 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:30259 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000445812 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:30259 "CG10352, Phos10352" "IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG10352 11-Aug-17 DroID_v2017_08 "Drer\pdxp, Drer\lhpp, Drer\pgp" Scer\PHO13 "Cele\C13C4.4, Cele\K02D10.1, Cele\F44E7.2, Cele\C53A3.2, Cele\C45E5.1, Cele\K09H11.7" - "Mmus\Lhpp, Mmus\Pdxp, Mmus\Pgp" "Hsap\LHPP, Hsap\PGP, Hsap\PDXP" viable FBgn0042182 CG18749 - http://flybase.org/reports/FBgn0042182 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 extracellular region ; GO:0005576 | inferred from sequence model "CG31188, CG18238, CG18749" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG18749 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\p4ha1a, Drer\zgc:152670, Drer\p4htm, Drer\p4ha3, Drer\zgc:158254, Drer\p4ha2" - "Cele\phy-4, Cele\dpy-18, Cele\C14E2.4, Cele\phy-3, Cele\phy-2, Cele\Y43F8B.19" "Xtro\p4ha3, Xtro\p4ha1, Xtro\p4ha2" "Mmus\P4ha3, Mmus\P4ha2, Mmus\P4htm, Mmus\P4ha1" "Hsap\P4HA2, Hsap\P4HTM, Hsap\P4HA1, Hsap\P4HA3" "viable,fertile" FBgn0040842 CG15212 - http://flybase.org/reports/FBgn0040842 protein_coding_gene - - - "BcDNA:RE28658, CG15212" - CG15212 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0033494 KCNQ KCNQ potassium channel http://flybase.org/reports/FBgn0033494 protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000164970 voltage-gated cation channel activity ; GO:0022843 | inferred from direct assay regulation of heart rate ; GO:0002027 | inferred from mutant phenotype cardiac muscle contraction ; GO:0060048 | inferred from mutant phenotype potassium ion transmembrane transport ; GO:0071805 | inferred from biological aspect of ancestor with PANTHER:PTN000164970 embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from direct assay voltage-gated potassium channel complex ; GO:0008076 | inferred from electronic annotation with InterPro:IPR028325 integral component of membrane ; GO:0016021 | inferred from direct assay "CG12215, DKCNQ, CG12915, CG33135, KCNQ, dKCNQ, kcnq1, KQT 1, KQT" "IPR028325:Voltage-gated potassium channel, IPR003937:Potassium channel, voltage dependent, KCNQ, IPR005821:Ion transport domain, IPR013821:Potassium channel, voltage dependent, KCNQ, C-terminal" CG33135 11-Aug-17 DroID_v2017_08 "Drer\kcnq5a, Drer\kcnq3, Drer\kcnq1, Drer\zmp:0000000932, Drer\kcnq5b, Drer\kcnq2a" - "Cele\kqt-3, Cele\kqt-2, Cele\kqt-1" "Xtro\kcnq1, Xtro\kcnq4" "Mmus\Kcnq2, Mmus\Kcnq3, Mmus\Kcnq5, Mmus\Kcnq4, Mmus\Kcnq1" "Hsap\KCNQ3, Hsap\KCNQ5, Hsap\KCNQ1, Hsap\KCNQ2, Hsap\KCNQ4" "viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,short lived,female,developmental rate defective,lethal" "cleavage nucleus,maternal effect,adult heart,conditional,adult heart muscle" DRSC06230 I 1.831596872 -0.689739691 -0.565086924 0.170453038 0.293685309 0.060176551 FBgn0022294 l(1)M86.4 lethal (1) M86.4 http://flybase.org/reports/FBgn0022294 - gene - - - "M86.4, l(1)M86.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040972 CG16978 - http://flybase.org/reports/FBgn0040972 protein_coding_gene - - - "CT35582, CG16978" - CG16978 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014956 exu::Dpse\exu1 exu1 http://flybase.org/reports/FBgn0014956 - engineered_fusion_gene - - - exu::Dpse\exu1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003623 Su(var)302 Suppressor of variegation 302 http://flybase.org/reports/FBgn0003623 - gene - - - Su(var)302 - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,viable" FBgn0259524 B2004 - http://flybase.org/reports/FBgn0259524 gene - - - B2004 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,submarginal cell" FBgn0025500 l(3)73An lethal (3) 73An http://flybase.org/reports/FBgn0025500 - gene - - - l(3)73An - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259383 C549 - http://flybase.org/reports/FBgn0259383 gene - - - C549 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0043563 Su(hh)IV Su(hh)IV http://flybase.org/reports/FBgn0043563 gene - - - Su(hh)IV - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0020587 anon-57Cj anon-57Cj http://flybase.org/reports/FBgn0020587 - gene - - - anon-57Cj - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263988 Dic61B Dynein intermediate chain at 61B http://flybase.org/reports/FBgn0263988 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatogenesis ; GO:0007283 | inferred from mutant phenotype cilium movement ; GO:0003341 | inferred from direct assay axonemal dynein complex ; GO:0005858 | inferred from direct assay "Dic61B, CG7051, ms(3)21, ms" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7051 11-Aug-17 DroID_v2017_08 Drer\wdr78 - - Xtro\wdr78 "Mmus\Wdr78, Mmus\Dnaic1" "Hsap\WDR78, Hsap\DNAI1" FBgn0031244 CG11601 - http://flybase.org/reports/FBgn0031244 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006838 CG11601 IPR006838:FAR-17a/AIG1-like protein CG11601 11-Aug-17 DroID_v2017_08 "Drer\zgc:112175, Drer\mybl2a, Drer\LOC100537455, Drer\aig1" Scer\YHR140W "Cele\C37E2.3, Cele\cTel55X.1, Cele\C37E2.2" Xtro\myo15a "Mmus\Adtrp, Mmus\Aig1" "Hsap\AIG1, Hsap\ADTRP" viable DRSC00318 I 1.687914103 -0.200652215 0.252627309 0.094928164 0.131270734 -1.174901681 FBgn0003181 pys polychaetous http://flybase.org/reports/FBgn0003181 - gene - - - pys - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive" "macrochaeta,heat sensitive" FBgn0013804 Dew Dew http://flybase.org/reports/FBgn0013804 - gene - - - Dew - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261860 CG42789 - http://flybase.org/reports/FBgn0261860 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42789, DMG8-chr3R.40.015, DMG8-chr3R.40.015-MIP08885, lincRNA.863" - CG42789 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022780 Hypnos-1 "Hypoxia, anoxia, sensitive 1" http://flybase.org/reports/FBgn0022780 - gene - response to hypoxia ; GO:0001666 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | traceable author statement - "hypnos-1, Hypnos-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,dominant,neurophysiology defective" adult central nervous system FBgn0035922 Pex7 Peroxin 7 http://flybase.org/reports/FBgn0035922 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8860 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8860 "CG6486, PEX7, Pex7, DmelPex7" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG6486 11-Aug-17 DroID_v2017_08 Drer\pex7 "Scer\RAD28, Scer\PEX7" - Xtro\pex7 Mmus\Pex7 "Hsap\PEX7, Hsap\APAF1" "viable,body color defective" mesothoracic tergum FBgn0069207 l(2)46CDa lethal (2) 46CDa http://flybase.org/reports/FBgn0069207 gene - - - l(2)46CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,dominant" wing FBgn0061092 l(3)S011130b lethal (3) S011130b http://flybase.org/reports/FBgn0061092 gene - - - "0111/30, l(3)S011130b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041770 anon-d34 anon-d34 http://flybase.org/reports/FBgn0041770 gene - - - "d34, anon-d34" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250846 glob2 globin 2 http://flybase.org/reports/FBgn0250846 protein_coding_gene "oxygen binding ; GO:0019825 | inferred from electronic annotation with InterPro:IPR000971, InterPro:IPR012292 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR000971, InterPro:IPR012292 heme binding ; GO:0020037 | inferred from sequence model oxygen binding ; GO:0019825 | inferred from sequence model" - nucleus ; GO:0005634 | inferred from sequence model "anon-SAGE:Wang-121, glob2, CG15180, DmeGb2" "IPR009050:Globin-like, IPR000971:Globin" CG15180 11-Aug-17 DroID_v2017_08 - - - Xtro\hba3 - - FBgn0000243 Beadexoid Beadexoid http://flybase.org/reports/FBgn0000243 - gene - - - "Beadexoid, Bxd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" wing FBgn0060383 l(3)S134505 lethal (3) S134505 http://flybase.org/reports/FBgn0060383 gene - - - "1345/05, l(3)S134505" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004499 fs(1)2448 female sterile (1) 2448 http://flybase.org/reports/FBgn0004499 - gene - - - fs(1)2448 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085477 CG34448 - http://flybase.org/reports/FBgn0085477 protein_coding_gene triglyceride lipase activity ; GO:0004806 | inferred from sequence or structural similarity with UniProtKB:P81139 lipid metabolic process ; GO:0006629 | inferred from sequence or structural similarity with UniProtKB:P81139 cellular_component ; GO:0005575 | no biological data available "CG34448, CG31684, CG9966" "IPR033906:Lipase, N-terminal, IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG34448 11-Aug-17 DroID_v2017_08 "Drer\lipg, Drer\lpl, Drer\lipia, Drer\LOC100331214, Drer\lipib, Drer\lipca, Drer\LOC101884800, Drer\pla1a" - "Cele\lips-15, Cele\lips-13, Cele\lips-11, Cele\lips-12" "Xtro\lipg, Xtro\lpl" "Mmus\Pnliprp1, Mmus\Pnliprp2, Mmus\Lipg, Mmus\Liph, Mmus\Lipi, Mmus\Lipc, Mmus\Lpl, Mmus\Pla1a, Mmus\Pnlip" "Hsap\LIPI, Hsap\PNLIPRP2, Hsap\LIPH, Hsap\PNLIPRP3, Hsap\PLA1A, Hsap\LIPC, Hsap\PNLIPRP1, Hsap\LIPG, Hsap\LPL, Hsap\PNLIP" FBgn0037645 CG11966 - http://flybase.org/reports/FBgn0037645 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG11966 IPR013087:Zinc finger C2H2-type CG11966 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-253d23.2, Drer\LOC100535506, Drer\zgc:113452, Drer\si:dkeyp-2e4.8, Drer\zgc:171422, Drer\zgc:174623" Scer\ZAP1 "Cele\ztf-23, Cele\ztf-2, Cele\let-391, Cele\odd-1, Cele\odd-2" - Mmus\Zfp212 Hsap\ZNF212 "lethal,increased cell death" "ventral nerve cord,ventral nerve cord commissure,ventral midline,eye" FBgn0042648 elav::Hsap\ELAVL4 ELAVL4 http://flybase.org/reports/FBgn0042648 engineered_fusion_gene - - - elav::Hsap\ELAVL4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014121 anon-96Ff anon-96Ff http://flybase.org/reports/FBgn0014121 - gene - - - anon-96Ff - - 11-Aug-17 DroID_v2017_08 - - - - - - larval stage eye-antennal disc

FBgn0085261 CG34232 - http://flybase.org/reports/FBgn0085261 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34232 - CG34232 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086451 l(2)k09022 lethal (2) k09022 http://flybase.org/reports/FBgn0086451 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000335845 "positive regulation of transcription from RNA polymerase I promoter ; GO:0045943 | inferred from biological aspect of ancestor with PANTHER:PTN000335845 cellular response to starvation ; GO:0009267 | inferred from expression pattern maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000335845 neurogenesis ; GO:0022008 | inferred from mutant phenotype" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000335845 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000335845 t-UTP complex ; GO:0034455 | inferred from biological aspect of ancestor with PANTHER:PTN000335845 "CG10805, anon-WO0118547.160, l(2)k09022" "IPR011989:Armadillo-like helical, IPR012954:BP28, C-terminal domain, IPR016024:Armadillo-type fold, IPR022125:U3 small nucleolar RNA-associated protein 10" CG10805 11-Aug-17 DroID_v2017_08 Drer\heatr1 Scer\UTP10 Cele\toe-1 - Mmus\Heatr1 Hsap\HEATR1 FBgn0266371 CR45015 - http://flybase.org/reports/FBgn0266371 non_protein_coding_gene - - - CR45015 - CR45015 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065293 l(2)SH2003 lethal (2) SH2003 http://flybase.org/reports/FBgn0065293 gene - - - "l(2)SH2003, l(2)SH2 2003" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021973 l(2)k09935 lethal (2) k09935 http://flybase.org/reports/FBgn0021973 - gene - - - l(2)k09935 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061504 l(2)44Fl lethal (2) 44Fl http://flybase.org/reports/FBgn0061504 gene - - - l(2)44Fl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266065 CR44818 - http://flybase.org/reports/FBgn0266065 non_protein_coding_gene - - - CR44818 - CR44818 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024687 jok just odd knobs http://flybase.org/reports/FBgn0024687 - gene molecular_function ; GO:0003674 | no biological data available Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available jok - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "Bolwig nerve,photoreceptor cell" FBgn0264826 CR44034 - http://flybase.org/reports/FBgn0264826 non_protein_coding_gene - - - CR44034 - CR44034 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016640 ER2-4 ER2-4 http://flybase.org/reports/FBgn0016640 - gene - - - ER2-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023148 Su(mg)3-4 Suppressor of modifier of gypsy 3-4 http://flybase.org/reports/FBgn0023148 - gene - - - Su(mg)3-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267130 CR45570 - http://flybase.org/reports/FBgn0267130 non_protein_coding_gene - - - CR45570 - CR45570 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036494 Toll-6 Toll-6 http://flybase.org/reports/FBgn0036494 protein_coding_gene neurotrophin receptor activity ; GO:0005030 | inferred from mutant phenotype "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000157 convergent extension ; GO:0060026 | inferred from genetic interaction with 18w, Tollo axis elongation ; GO:0003401 | inferred from genetic interaction with 18w, Tollo dendrite guidance ; GO:0070983 | inferred from mutant phenotype" - "Toll-6, dToll6, toll, dTLR6, Tl-6, CT22359, 18w-like, CG7250, TOLL 6, toll-6, Toll 6" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG7250 11-Aug-17 DroID_v2017_08 "Drer\tlr3, Drer\tlr21, Drer\tlr9, Drer\lrrn1, Drer\zmp:0000001073, Drer\tlr5a, Drer\lgi1b, Drer\tlr5b, Drer\lgi3, Drer\si:dkey-182i3.11, Drer\lgi2a, Drer\lgi1a, Drer\zgc:101569, Drer\tlr4bb, Drer\lrrc4bb, Drer\tlr2, Drer\LOC572462, Drer\tlr4ba, Drer\tlr7, Drer\tlr18, Drer\LOC100005571, Drer\tlr1, Drer\tlr8b, Drer\LOC100332583, Drer\LOC100332783, Drer\tlr20.2, Drer\lrrc23, Drer\cd180, Drer\lrfn4a" - "Cele\tol-1, Cele\sym-1" "Xtro\tlr6, Xtro\LOC100485201, Xtro\tlr2, Xtro\LOC100495326, Xtro\tlr5, Xtro\lrfn5, Xtro\tlr7, Xtro\lrfn2, Xtro\LOC100485706, Xtro\tlr9, Xtro\tlr3, Xtro\lrrn1-like, Xtro\LOC100485512, Xtro\LOC100485164" "Mmus\Tlr2, Mmus\Il1rapl2, Mmus\Cd180, Mmus\Lgi3, Mmus\Lingo3, Mmus\Lrfn5, Mmus\Tlr7, Mmus\Tlr1, Mmus\Tlr5, Mmus\Lgi1, Mmus\Nepn, Mmus\Tlr13, Mmus\Lgi2, Mmus\Tlr8, Mmus\Tlr12, Mmus\Lrrc23, Mmus\Lgi4, Mmus\Tlr3, Mmus\Tlr9, Mmus\Lrrn3, Mmus\Tlr6, Mmus\Tlr4" "Hsap\TLR4, Hsap\CD180, Hsap\LGI4, Hsap\CHADL, Hsap\LRRC23, Hsap\TLR9, Hsap\FBXL14, Hsap\TLR10, Hsap\LRRN3, Hsap\TLR7, Hsap\LRFN1, Hsap\IL1RAPL2, Hsap\LGI1, Hsap\LINGO3, Hsap\FBXL13, Hsap\LRFN5, Hsap\LGI3, Hsap\TLR1, Hsap\TLR3, Hsap\TLR2, Hsap\TLR8, Hsap\TLR6, Hsap\LGI2, Hsap\TLR5" " embryonic stage , embryonic stage -- adult stage " "lethal,viable,fertile,neuroanatomy defective,decreased cell death,visible" "adult abdomen,macrochaeta,ectopic,eye,wing vein,leg,wing,wing disc,embryonic/larval central nervous system,trichogen cell" DRSC11304 E 1.373948068 0.469184431 3.237089089 0.088044673 1.488651526 -0.111272897 FBgn0011774 Irbp Inverted repeat-binding protein http://flybase.org/reports/FBgn0011774 "FBgn0004048, FBgn0011292" protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR006165 ATP-dependent DNA helicase activity ; GO:0004003 | inferred from electronic annotation with InterPro:IPR005160 protein heterodimerization activity ; GO:0046982 | inferred from direct assay DNA binding ; GO:0003677 | contributes_to inferred from direct assay DNA binding ; GO:0003677 | inferred from sequence or structural similarity with HGNC:4055 inferred from direct assay telomeric DNA binding ; GO:0042162 | inferred from biological aspect of ancestor with PANTHER:PTN000288287 DNA binding ; GO:0003677 | inferred from direct assay double-strand break repair via nonhomologous end joining ; GO:0006303 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from mutant phenotype "Ku70:Ku80 complex ; GO:0043564 | inferred from direct assay nuclear chromosome, telomeric region ; GO:0000784 | inferred from biological aspect of ancestor with PANTHER:PTN000288287" "Ku70, DmKu70, YPF1, dp70, IRBP, Ku, IRBP/Ku70, p70, YPF1beta, Ypf1b, CG5247, Irbp, ku70, irbp" "IPR005160:Ku70/Ku80 C-terminal arm, IPR005161:Ku70/Ku80, N-terminal alpha/beta, IPR006164:Ku70/Ku80 beta-barrel domain, IPR006165:Ku70, IPR016194:SPOC-like, C-terminal domain, IPR002035:von Willebrand factor, type A" CG5247 11-Aug-17 DroID_v2017_08 Drer\xrcc6 Scer\YKU70 Cele\cku-70 Xtro\xrcc6 Mmus\Xrcc6 Hsap\XRCC6 "radiation sensitive,recessive,chemical sensitive,visible,wild-type,viable" "macrochaeta,supernumerary,adult thoracic sensillum" FBgn0015944 gang-of-three gang of three http://flybase.org/reports/FBgn0015944 - gene - - - gang-of-three - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014177 ftz::Scr ftz::Scr http://flybase.org/reports/FBgn0014177 - engineered_fusion_gene - - - ftz::Scr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032986 CG3262 - http://flybase.org/reports/FBgn0032986 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000808 - - CG3262 "IPR000808:Mrp, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033756:Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35, IPR019591:Mrp/NBP35 ATP-binding protein" CG3262 11-Aug-17 DroID_v2017_08 "Drer\nubp1, Drer\nubpl" "Scer\NBP35, Scer\CFD1" Cele\nubp-1 Xtro\nubpl "Mmus\Nubp2, Mmus\Nubpl, Mmus\Nubp1" "Hsap\NUBPL, Hsap\NUBP1, Hsap\NUBP2" FBgn0034768 Obp58b Odorant-binding protein 58b http://flybase.org/reports/FBgn0034768 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "CG13518, Obp58b, DmelObp58b, C13518" IPR006170:Pheromone/general odorant binding protein CG13518 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033371 CNT1 Concentrative nucleoside transporter 1 http://flybase.org/reports/FBgn0033371 protein_coding_gene nucleoside:sodium symporter activity ; GO:0005415 | inferred from biological aspect of ancestor with PANTHER:PTN000834192 nucleoside transmembrane transport ; GO:1901642 | inferred from electronic annotation with InterPro:IPR008276 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000063482 "CG11778, CNT1, DmCnt1" "IPR002668:Concentrative nucleoside transporter N-terminal domain, IPR008276:Concentrative nucleoside transporter, IPR011657:Concentrative nucleoside transporter C-terminal domain" CG11778 11-Aug-17 DroID_v2017_08 Drer\slc28a1 - "Cele\slc-28.1, Cele\slc-28.2" "Xtro\slc28a2, Xtro\slc28a3" "Mmus\Slc28a3, Mmus\Gm14085, Mmus\Slc28a2, Mmus\Slc28a1" "Hsap\SLC28A2, Hsap\SLC28A3, Hsap\SLC28A1" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC06082 K -0.214426719 0.426565797 0.73561061 -0.144935321 1.230353934 -1.679888064 FBgn0044810 TotX Turandot X http://flybase.org/reports/FBgn0044810 protein_coding_gene - cellular response to oxidative stress ; GO:0034599 | inferred from expression pattern cellular response to heat ; GO:0034605 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from expression pattern response to oxidative stress ; GO:0006979 | inferred from direct assay response to heat ; GO:0009408 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence or structural similarity with TotA extracellular region ; GO:0005576 | inferred from sequence model "TotX, tot, CG31193, Tot X, TOTX" IPR010825:Stress-inducible humoral factor Turandot CG31193 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070002 BG01572 BG01572 http://flybase.org/reports/FBgn0070002 gene - - - BG01572 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0022214 l(2)k03706 lethal (2) k03706 http://flybase.org/reports/FBgn0022214 - gene - - - l(2)k03706 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031697 CG14024 - http://flybase.org/reports/FBgn0031697 protein_coding_gene "sulfotransferase activity ; GO:0008146 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR018011" carbohydrate biosynthetic process ; GO:0016051 | inferred from electronic annotation with InterPro:IPR018011 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR018011" "CG14024, d4ST1" "IPR005331:Sulfotransferase, IPR018011:Carbohydrate sulfotransferase 8-10" CG14024 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-26i13.6, Drer\si:dkey-26i13.7, Drer\chst12b, Drer\si:dkey-26i13.3, Drer\chst14, Drer\si:ch211-269c21.2, Drer\chst12a, Drer\LOC100536144, Drer\chst11, Drer\si:dkey-26i13.4, Drer\si:dkey-26i13.5, Drer\si:ch211-236h17.3, Drer\chst8, Drer\chst10" - "Cele\F49D11.6, Cele\F56H6.4" "Xtro\chst12, Xtro\chst8, Xtro\chst13, Xtro\chst11, Xtro\chst14" "Mmus\Chst10, Mmus\Chst11, Mmus\Chst8, Mmus\Chst13, Mmus\Chst12, Mmus\Chst9, Mmus\Chst14" "Hsap\CHST8, Hsap\CHST11, Hsap\CHST14, Hsap\CHST9, Hsap\CHST13, Hsap\CHST10, Hsap\CHST12" viable FBgn0065692 l(2)SH0642 lethal (2) SH0642 http://flybase.org/reports/FBgn0065692 gene - - - "l(2)SH0642, l(2)SH2 0642" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260100 2L0058 - http://flybase.org/reports/FBgn0260100 gene - "dorsal trunk growth, open tracheal system ; GO:0035001 | inferred from mutant phenotype" - 2L0058 - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethalcell lethal,somatic clone" embryonic/larval dorsal trunk FBgn0037371 Sym Symplekin http://flybase.org/reports/FBgn0037371 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z802 inferred from physical interaction with UniProtKB:Q9V3D6 inferred from physical interaction with UniProtKB:Q9VAN6 inferred from physical interaction with UniProtKB:Q9VE51 mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype histone locus body ; GO:0035363 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay tricellular tight junction ; GO:0061689 | inferred from direct assay mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from direct assay "Sym, CG2097, dSymp, Symp" "IPR016024:Armadillo-type fold, IPR021850:Symplekin/Pta1, IPR022075:Symplekin C-terminal, IPR011989:Armadillo-like helical, IPR032460:Symplekin/Pta1, N-terminal" CG2097 11-Aug-17 DroID_v2017_08 Drer\sympk Scer\PTA1 Cele\symk-1 Xtro\sympk Mmus\Sympk Hsap\SYMPK "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0026720 fs(1)pyr fs(1)pyr http://flybase.org/reports/FBgn0026720 - gene - - - fs(1)pyr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267952 CR46232 - http://flybase.org/reports/FBgn0267952 pseudogene_attribute - - - "CR46232, lincRNA.880" - CR46232 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002021 l(2)37Bb lethal (2) 37Bb http://flybase.org/reports/FBgn0002021 FBgn0032747 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000354057 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR023753 mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from biological aspect of ancestor with PANTHER:PTN000354502" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000354502 "l(2)35B2, CG10655, Bb, l(2)E58, l(2)37Bb" "IPR006076:FAD dependent oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG10655 11-Aug-17 DroID_v2017_08 Drer\foxred1 - Cele\M04B2.4 Xtro\foxred1 Mmus\Foxred1 Hsap\FOXRED1 "lethal,recessive,wild-type,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,viable,female fertile,female sterile" "adult thorax,imaginal disc,embryonic/larval salivary gland,embryonic/larval fat body" FBgn0060845 l(3)S049009b lethal (3) S049009b http://flybase.org/reports/FBgn0060845 gene - - - "0490/09, l(3)S049009b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082931 snoRNA:Me28S-G2703a snoRNA:Me28S-G2703a http://flybase.org/reports/FBgn0082931 snoRNA_gene - - - "snoRNA:Me28S-G2703a, Me28S-Gm2703a, Me28S-G2703a, CR34539, chr2R:10138338..10138435" - CR34539 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029931 CG14427 - http://flybase.org/reports/FBgn0029931 protein_coding_gene - - - CG14427 - CG14427 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0016793 dog dog of glass http://flybase.org/reports/FBgn0016793 - gene molecular_function ; GO:0003674 | no biological data available compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available dog - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265367 CR44308 - http://flybase.org/reports/FBgn0265367 non_protein_coding_gene - - - "CR44308, lincRNA.21" - CR44308 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002266 l(3)69Ae lethal (3) 69Ae http://flybase.org/reports/FBgn0002266 - gene - - - "rsg28, l(3)rsg28, l(3)69Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039663 CG2321 - http://flybase.org/reports/FBgn0039663 protein_coding_gene - - - CG2321 "IPR029269:Putative treble-clef, zinc-finger domain, IPR026049:Uncharacterised protein C2orf42" CG2321 11-Aug-17 DroID_v2017_08 Drer\si:ch211-127d4.3 - - Xtro\c2orf42 Mmus\C87436 Hsap\C2orf42 "viable,visible" trichogen cell FBgn0266938 CR45389 - http://flybase.org/reports/FBgn0266938 non_protein_coding_gene - - - CR45389 - CR45389 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264827 CR44035 - http://flybase.org/reports/FBgn0264827 non_protein_coding_gene - - - CR44035 - CR44035 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001421 l(1)6De lethal (1) 6De http://flybase.org/reports/FBgn0001421 - gene - - - "l(1)EM25, l(1)6De" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005461 l(1)ts13 lethal (1) ts13 http://flybase.org/reports/FBgn0005461 - gene - - - l(1)ts13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0028056 l(3)S094310 lethal (3) S094310 http://flybase.org/reports/FBgn0028056 gene - - - "943/10, 0943/10, l(3)S094310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011962 tRNA:Arg-ACG-1-7 transfer RNA:Arginine-ACG 1-7 http://flybase.org/reports/FBgn0011962 "FBgn0003758, FBgn0011947, FBgn0051585, FBgn0060094" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "tRNA[arg], tRNA[Arg][[2]], AE002708.trna65-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002708-d, CR31585, tRNA:arg2:84Fd, chr3R.trna71-ArgACG, tRNA-Arg-ACG-1-7, tRNA:Arg-ACG-1-7, tRNA:R2:84Fd, CGU" - CR31585 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051226 CG31226 - http://flybase.org/reports/FBgn0051226 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs14h12, BcDNA:AT26083, CG31226" - CG31226 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC21724 I -1.672918703 0.560440944 -0.278229012 0.457068063 1.086903024 -0.604963711 FBgn0004372 aly always early http://flybase.org/reports/FBgn0004372 "FBgn0013662, FBgn0014354, FBgn0035387" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with tomb protein binding ; GO:0005515 | inferred from physical interaction with wuc "meiotic nuclear division ; GO:0007126 | traceable author statement spermatogenesis ; GO:0007283 | inferred from mutant phenotype male meiosis I ; GO:0007141 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype spermatid development ; GO:0007286 | traceable author statement positive regulation of transcription involved in meiotic cell cycle ; GO:0051039 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype chromatin organization ; GO:0006325 | non-traceable author statement spermatogenesis ; GO:0007283 | inferred from expression pattern DNA-templated transcription, initiation ; GO:0006352 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype" transcriptional repressor complex ; GO:0017053 | inferred from electronic annotation with InterPro:IPR010561 nucleus ; GO:0005634 | inferred from sequence or structural similarity inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "143450_at, CG2075, ms(3)ry2, ms(3)2, aly, Aly" "IPR010561:Protein LIN-9/Protein ALWAYS EARLY, IPR033471:DIRP domain" CG2075 11-Aug-17 DroID_v2017_08 Drer\lin9 - Cele\lin-9 Xtro\lin9 Mmus\Lin9 Hsap\LIN9 " adult stage | male , adult stage " " spermatocyte

, spermatid

" "viable,male sterile,fertile,recessive,meiotic cell cycle defective,lethal,heat sensitive" "testis,spermatocyte,nuclear chromosome & primary spermatocyte,heat sensitive" FBgn0052064 S-Lap4 Sperm-Leucylaminopeptidase 4 http://flybase.org/reports/FBgn0052064 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "CG8040, bs04d09.y1, anon-WO0140519.223, anon-WO0140519.141, CG32064, GH8, S-Lap4, S-LAP 4" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG32064 11-Aug-17 DroID_v2017_08 "Drer\npepl1, Drer\zgc:152830, Drer\rfwd2, Drer\lap3" - Cele\lap-1 "Xtro\lap3, Xtro\rfwd2" "Mmus\Npepl1, Mmus\Rfwd2, Mmus\Lap3" "Hsap\LAP3, Hsap\NPEPL1" viable DRSC10957 K -0.121583999 -0.026079136 0.166756726 0.554619282 -1.547797407 -1.251004022 FBgn0037563 CG11672 - http://flybase.org/reports/FBgn0037563 protein_coding_gene - - - "BcDNA:RE26525, CG11672" - CG11672 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051179 CG31179 - http://flybase.org/reports/FBgn0051179 protein_coding_gene - - - CG31179 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003629 Su(var)320 Suppressor of variegation 320 http://flybase.org/reports/FBgn0003629 - gene - - - Su(var)320 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant" FBgn0044392 Scim36 Sensitized chromosome inheritance modifier 36 http://flybase.org/reports/FBgn0044392 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim36 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0265310 CR44283 - http://flybase.org/reports/FBgn0265310 non_protein_coding_gene - - - CR44283 - CR44283 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058153 CG40153 - http://flybase.org/reports/FBgn0058153 protein_coding_gene - - - CG40153 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035945 CG5026 - http://flybase.org/reports/FBgn0035945 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from sequence model phosphatidylinositol-3-phosphatase activity ; GO:0004438 | inferred from sequence or structural similarity with SGD:S000003871 phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from sequence or structural similarity with SGD:S000003871 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003871 CG5026 "IPR010569:Myotubularin-like phosphatase domain, IPR030564:Myotubularin family, IPR011993:PH domain-like, IPR029021:Protein-tyrosine phosphatase-like" CG5026 11-Aug-17 DroID_v2017_08 "Drer\mtmr1b, Drer\mtmr9, Drer\mtmr7b, Drer\zgc:154055, Drer\mtmr8, Drer\mtmr6, Drer\mtmr7a, Drer\mtmr12, Drer\mtmr10, Drer\mtmr1a, Drer\mtmr2" Scer\YMR1 Cele\mtm-9 "Xtro\mtmr2, Xtro\mtm1, Xtro\mtmr7, Xtro\mtmr9, Xtro\mtmr12, Xtro\mtmr1, Xtro\mtmr6, Xtro\mtmr10, Xtro\asb12.2, Xtro\LOC100216114" "Mmus\Mtmr10, Mmus\Mtmr1, Mmus\Mtm1, Mmus\Mtmr11, Mmus\Mtmr6, Mmus\Mtmr2, Mmus\Mtmr12, Mmus\Mtmr9, Mmus\Mtmr7" "Hsap\MTMR6, Hsap\MTMR12, Hsap\MTMR8, Hsap\MTMR7, Hsap\MTMR11, Hsap\MTMR2, Hsap\MTMR1, Hsap\MTMR9, Hsap\MTMR10, Hsap\MTM1" "viable,fertile" FBgn0020860 curl-r "curl, recessive" http://flybase.org/reports/FBgn0020860 - gene - - - "curl-r, curl" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086080 snoRNA:Me28S-A576 - http://flybase.org/reports/FBgn0086080 snoRNA_gene - - - "snoRNA:Me28S-A576, Me28S-Am576, CR34709" - CR34709 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014957 exu::Dpse\exu2 exu2 http://flybase.org/reports/FBgn0014957 - engineered_fusion_gene - - - exu::Dpse\exu2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261271 esi-1 endogenous siRNA 1 http://flybase.org/reports/FBgn0261271 gene - - - "esi-1, hp-CG18854, hp-CG18854A, esi-1.1, esi-1.2, esiRNA-sl-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020824 l(3)98Dc lethal (3) 98Dc http://flybase.org/reports/FBgn0020824 - gene - - - "M318, l(3)M3-18, l(3)98D-Ec, l(3)98Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037773 CG5359 - http://flybase.org/reports/FBgn0037773 protein_coding_gene dynein intermediate chain binding ; GO:0045505 | inferred from sequence or structural similarity with Dlc90F microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with Dlc90F dynein complex ; GO:0030286 | inferred from sequence or structural similarity with Dlc90F "BcDNA:RE37471, CG5359" IPR005334:Tctex-1 CG5359 11-Aug-17 DroID_v2017_08 "Drer\tctex1d2, Drer\tctex1d1, Drer\dynlt3" - Cele\dylt-2 Xtro\tctex1d1 "Mmus\Tcte3, Mmus\Tctex1d1, Mmus\Gm3417, Mmus\Tctex1d2, Mmus\Gm3448, Mmus\Tctex1d4, Mmus\Dynlt3" "Hsap\DYNLT3, Hsap\TCTEX1D2, Hsap\TCTE3, Hsap\TCTEX1D4, Hsap\TCTEX1D1" "viable,fertile" DRSC15780 I 2.685271928 -0.003681487 -0.153713919 0.452736011 0.427391403 -0.921163961 FBgn0030319 CG2533 - http://flybase.org/reports/FBgn0030319 protein_coding_gene - - - "BcDNA:AT28768, CG2533" - CG2533 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC19855 K -0.008256799 0.501565821 -0.223310805 0.141557683 0.085907201 -2.032097368 FBgn0036667 CG9669 - http://flybase.org/reports/FBgn0036667 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9669 IPR007915:Transmembrane protein 258 CG9669 11-Aug-17 DroID_v2017_08 Drer\tmem258 - Cele\Y57E12AM.1 Xtro\tmem258 Mmus\Tmem258 Hsap\TMEM258 FBgn0020053 E(w[a])818 E(w[a])818 http://flybase.org/reports/FBgn0020053 - gene - - - "E818, E(w[a])818" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,eye color defective" pigment cell FBgn0060517 l(3)S103705b lethal (3) S103705b http://flybase.org/reports/FBgn0060517 gene - - - "1037/05, l(3)S103705b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0069350 Suppressor-of-Punch Suppressor of Punch http://flybase.org/reports/FBgn0069350 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available Suppressor-of-Punch - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044110 E(rst)C349 E(rst)C349 http://flybase.org/reports/FBgn0044110 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C349, E(rst)C349" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003374 Sgs4 Salivary gland secretion 4 http://flybase.org/reports/FBgn0003374 - protein_coding_gene - - - "Sgs-4, sgs4, sgs-4, Sgs, CG12181, SGS-4, EG:96G10.6, Sgs4, SGS4" - CG12181 11-Aug-17 DroID_v2017_08 Drer\si:ch73-269m14.2 - - - Mmus\9530068E07Rik "Hsap\CLEC4F, Hsap\PRB3, Hsap\C5orf15" larval stage | late third instar larval stage organism

larval stage | late third instar larval stage embryonic/larval salivary gland

electrophoretic variant FBgn0037449 CG15185 - http://flybase.org/reports/FBgn0037449 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15185 - CG15185 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030817 CG4991 - http://flybase.org/reports/FBgn0030817 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 "CT15971, CG4991" "IPR013057:Amino acid transporter, transmembrane domain" CG4991 11-Aug-17 DroID_v2017_08 "Drer\slc36a1, Drer\slc36a4" "Scer\AVT6, Scer\AVT3, Scer\AVT4" "Cele\slc-36.5, Cele\Y43F4B.7, Cele\slc-36.3, Cele\slc-36.4, Cele\slc-36.2, Cele\skat-1" "Xtro\slc36a4, Xtro\slc36a1" "Mmus\Slc36a1, Mmus\Slc36a3, Mmus\Slc36a2, Mmus\Slc36a4, Mmus\Slc38a7" "Hsap\SLC36A4, Hsap\SLC36A2, Hsap\SLC36A3, Hsap\SLC36A1, Hsap\SLC38A7" viable FBgn0001216 Hsc70-1 Heat shock protein cognate 1 http://flybase.org/reports/FBgn0001216 FBgn0064802 protein_coding_gene - protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P38646 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P38646 microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "143191_at, Hsc70, HSC-70, HSC70, Hsc1, hsc70, dhsc70, HSC1, CG8937, BcDNA:RH49358, Hsc70-1, HSC70-1, dhsc70-1, Hsp-c1, HSP7A_DROME, DmHsp70" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG8937 11-Aug-17 DroID_v2017_08 "Drer\hspa12a, Drer\si:ch211-199o1.2, Drer\hspa5, Drer\hsp70.2, Drer\hspa14, Drer\hsp70.1, Drer\hsp70l, Drer\nckap1, Drer\hspa12b, Drer\hspa13, Drer\hspa8, Drer\si:dkey-4p15.3, Drer\hsc70" "Scer\KAR2, Scer\SSA2, Scer\SSB2, Scer\SSA4, Scer\SSZ1, Scer\SSA1, Scer\SSB1, Scer\SSA3" "Cele\hsp-1, Cele\gex-3, Cele\hsp-3, Cele\F11F1.1, Cele\hsp-4, Cele\F44E5.5, Cele\F44E5.4, Cele\hsp-70" "Xtro\hspa13, Xtro\hspa14, Xtro\hspa8, Xtro\hspa12b, Xtro\hspa5, Xtro\hspa2, Xtro\nckap1l, Xtro\hsp70, Xtro\hspa1b, Xtro\hspa1a, Xtro\nckap1, Xtro\hspa1l" "Mmus\Hspa5, Mmus\Nckap1, Mmus\Hspa2, Mmus\Hspa13, Mmus\Hspa12b, Mmus\Hspa14, Mmus\Hspa1l, Mmus\Hspa12a, Mmus\Hspa8, Mmus\Hspa1a, Mmus\Hspa1b, Mmus\Nckap1l" "Hsap\NCKAP1L, Hsap\HSPA1A, Hsap\HSPA13, Hsap\HSPA5, Hsap\HSPA14, Hsap\HSPA8, Hsap\HSPA2, Hsap\NCKAP1, Hsap\HSPA12A, Hsap\HSPA1L, Hsap\HSPA1B, Hsap\HSPA12B, Hsap\HSPA6" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC11185 EK 0.36346297 -0.077429705 -0.08715295 -1.884926168 0.679487716 -1.532617542 FBgn0003494 split-thorax split thorax http://flybase.org/reports/FBgn0003494 - gene - - - "split-thorax, spx" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male,reduced,male fertile,female,poor,female fertile" "adult thorax,eye,wing,tergite" FBgn0031004 CG7992 - http://flybase.org/reports/FBgn0031004 protein_coding_gene - - - CG7992 - CG7992 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0264875 CR44066 - http://flybase.org/reports/FBgn0264875 non_protein_coding_gene - - - CR44066 - CR44066 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019744 l(1)89B lethal (1) 89B http://flybase.org/reports/FBgn0019744 - gene - - - l(1)89B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061499 l(2)45An lethal (2) 45An http://flybase.org/reports/FBgn0061499 gene - - - l(2)45An - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052753 CR32753 - http://flybase.org/reports/FBgn0052753 non_protein_coding_gene - - - CR32753 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041105 nerfin-2 nervous fingers 2 http://flybase.org/reports/FBgn0041105 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG12809, nerfin-2, Nerfin" IPR013087:Zinc finger C2H2-type CG12809 11-Aug-17 DroID_v2017_08 "Drer\insm1a, Drer\insm1b" - "Cele\ham-2, Cele\F26F4.8, Cele\egl-46" Xtro\insm2 "Mmus\Insm2, Mmus\Zfp667, Mmus\Insm1" "Hsap\INSM1, Hsap\ZNF667, Hsap\INSM2, Hsap\ZNF140" FBgn0259331 EP-3 - http://flybase.org/reports/FBgn0259331 gene - - - EP-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" wing vein FBgn0084011 CG41447 - http://flybase.org/reports/FBgn0084011 protein_coding_gene - - - CG41447 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034047 CG12970 - http://flybase.org/reports/FBgn0034047 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12970 IPR024810:Mab-21 domain CG12970 11-Aug-17 DroID_v2017_08 Drer\mb21d1 - - - Mmus\Mb21d1 Hsap\MB21D1 "viable,visible" "trichogen cell,supernumerary" FBgn0260646 CG42538 - http://flybase.org/reports/FBgn0260646 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG42538 IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42538 11-Aug-17 DroID_v2017_08 "Drer\glipr2l, Drer\pi15b, Drer\tfpi2, Drer\glipr1b, Drer\crispld1b, Drer\r3hdml, Drer\pi15a, Drer\ambp, Drer\crispld2, Drer\crispld1a, Drer\glipr2, Drer\LOC100536500" "Scer\PRY1, Scer\PRY2, Scer\PRY3" - "Xtro\MGC108118, Xtro\crispld2, Xtro\crisp1, Xtro\r3hdml, Xtro\crisp3, Xtro\crisp2, Xtro\glipr2" "Mmus\Crispld2, Mmus\Crispld1, Mmus\Pi15, Mmus\Crisp3, Mmus\R3hdml, Mmus\Crisp2, Mmus\Ambp, Mmus\Crisp4, Mmus\Spint4, Mmus\Glipr2, Mmus\Tfpi, Mmus\Glipr1l1, Mmus\Glipr1, Mmus\Pi16, Mmus\Clec18a, Mmus\Glipr1l2, Mmus\Crisp1" "Hsap\CRISPLD2, Hsap\SPINT4, Hsap\CRISPLD1, Hsap\GLIPR2, Hsap\AMBP, Hsap\PI15, Hsap\CLEC18C, Hsap\GLIPR1, Hsap\TFPI, Hsap\CLEC18A, Hsap\R3HDML, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\CRISP2, Hsap\CRISP1, Hsap\PI16, Hsap\CLEC18B" FBgn0000267 cbf clubfoot http://flybase.org/reports/FBgn0000267 - gene - - - cbf - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "leg,tarsal segment,wing" FBgn0060918 l(3)S042606 lethal (3) S042606 http://flybase.org/reports/FBgn0060918 gene - - - "0426/06, l(3)S042606" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0013315 Pbp27 Phenylalkylamine binding protein-27kD http://flybase.org/reports/FBgn0013315 - gene phenylalkylamine binding ; GO:0008145 | inferred from direct assay - - Pbp27 - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult head

FBgn0265372 CR44313 - http://flybase.org/reports/FBgn0265372 non_protein_coding_gene - - - "CR44313, lincRNA.290" - CR44313 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038942 CG13862 - http://flybase.org/reports/FBgn0038942 protein_coding_gene - - - CG13862 - CG13862 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031694 Cyp4ac2 Cyp4ac2 http://flybase.org/reports/FBgn0031694 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4ac2, CG17970, Cyp4ac2, CYP4ac2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG17970 11-Aug-17 DroID_v2017_08 "Drer\cyp19a1b, Drer\cyp4v7, Drer\cyp4v8, Drer\cyp3c3, Drer\cyp3c2, Drer\cyp26c1, Drer\cyp26a1, Drer\cyp4t8, Drer\LOC100329425, Drer\cyp46a1.3, Drer\cyp3c1, Drer\cyp19a1a, Drer\cyp3c4, Drer\cyp4f3, Drer\cyp46a1.4, Drer\cyp46a1.2, Drer\cyp20a1, Drer\cyp26b1, Drer\cyp3a65, Drer\cyp46a1.1" "Scer\DIT2, Scer\ERG5" "Cele\cyp-31A5, Cele\cyp-29A4, Cele\cyp-32B1, Cele\cyp-25A2, Cele\cyp-13A12, Cele\cyp-31A2, Cele\cyp-13A3, Cele\cyp-13A11, Cele\cyp-29A2, Cele\cyp-25A4, Cele\cyp-13A8, Cele\cyp-25A3, Cele\cyp-29A3, Cele\cyp-33C11, Cele\cyp-13A7, Cele\cyp-13A10, Cele\cyp-42A1, Cele\cyp-13A1, Cele\cyp-31A3, Cele\cyp-37A1, Cele\cyp-25A1, Cele\cyp-13A5, Cele\cyp-32A1, Cele\cyp-13A4, Cele\cyp-37B1" "Xtro\cyp19a1, Xtro\cyp4v2, Xtro\LOC100487918, Xtro\cyp4b1.2, Xtro\mgc108213, Xtro\cyp26a1, Xtro\cyp4f22, Xtro\cyp26b1, Xtro\cyp26c1, Xtro\LOC100488227, Xtro\cyp4f2, Xtro\cyp4b1, Xtro\cyp20a1" "Mmus\Cyp4f15, Mmus\Cyp4a12b, Mmus\Cyp26a1, Mmus\Cyp3a16, Mmus\Cyp4x1, Mmus\Cyp3a41b, Mmus\Cyp4f16, Mmus\Cyp26c1, Mmus\Cyp4a14, Mmus\Cyp3a25, Mmus\Cyp4a10, Mmus\Cyp4a31, Mmus\Cyp4f39, Mmus\Cyp4v3, Mmus\Cyp4f37, Mmus\Cyp19a1, Mmus\Cyp4a32, Mmus\Cyp4f40, Mmus\Cyp20a1, Mmus\Cyp26b1, Mmus\Cyp3a59, Mmus\Cyp4f14, Mmus\Cyp4f13, Mmus\Cyp46a1, Mmus\Cyp4a30b, Mmus\Cyp4f18, Mmus\Cyp3a13, Mmus\Cyp3a41a, Mmus\Cyp3a57, Mmus\Cyp4f17, Mmus\Cyp2b9, Mmus\Cyp3a44, Mmus\Cyp4a12a, Mmus\Cyp4b1, Mmus\Cyp3a11, Mmus\Cyp4a29" "Hsap\CYP3A5, Hsap\CYP4A11, Hsap\CYP4F22, Hsap\CYP19A1, Hsap\CYP26A1, Hsap\CYP26B1, Hsap\CYP4F12, Hsap\CYP4Z1, Hsap\CYP4F3, Hsap\CYP3A43, Hsap\CYP3A4, Hsap\CYP46A1, Hsap\CYP4F2, Hsap\CYP3A7, Hsap\CYP26C1, Hsap\CYP4V2, Hsap\CYP4A22, Hsap\CYP4F11, Hsap\CYP4B1, Hsap\CYP20A1, Hsap\CYP4X1, Hsap\CYP4F8" viable DRSC03303 K -0.997974232 0.37023727 -0.235738006 -0.507348396 -0.209930826 -2.070454368 FBgn0044344 springer\env springer element env http://flybase.org/reports/FBgn0044344 transposable_element_gene - - - "ORF3, springer\env" IPR009882:Gypsy - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040653 IM4 Immune induced molecule 4 http://flybase.org/reports/FBgn0040653 protein_coding_gene - defense response ; GO:0006952 | non-traceable author statement cell morphogenesis ; GO:0000902 | inferred from mutant phenotype humoral immune response ; GO:0006959 | inferred from expression pattern defense response ; GO:0006952 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern extracellular region ; GO:0005576 | non-traceable author statement extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG15231, DIM4, DIM-4, BcDNA:RH25931, IM4, DIM 4" - CG15231 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0066128 E(sda)F E(sda)F http://flybase.org/reports/FBgn0066128 gene molecular_function ; GO:0003674 | no biological data available mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E(sda)F, Line F" - - 11-Aug-17 DroID_v2017_08 - - - - - - bang sensitive FBgn0284252 Letm1 Leucine zipper and EF-hand containing transmembrane protein 1 http://flybase.org/reports/FBgn0284252 protein_coding_gene ribosome binding ; GO:0043022 | inferred from electronic annotation with InterPro:IPR033122 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium:sodium antiporter activity ; GO:0005432 | inferred from direct assay potassium:proton antiporter activity ; GO:0015386 | inferred from mutant phenotype potassium ion transmembrane transport ; GO:0071805 | inferred from mutant phenotype hydrogen ion transmembrane transport ; GO:1902600 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype mitochondrial calcium ion transport ; GO:0006851 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial membrane ; GO:0031966 | inferred from direct assay "Letm1, l(2)k10502, letm1, CG4589, B4D, anon-60Da, anon60Da, dLetm1, DmLETM1" "IPR033122:Letm1 ribosome-binding domain, IPR002048:EF-hand domain, IPR011685:LETM1-like, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG4589 11-Aug-17 DroID_v2017_08 "Drer\letm1, Drer\letm2" "Scer\YLH47, Scer\MDM38, Scer\USO1" Cele\letm-1 "Xtro\letm2, Xtro\letm1" "Mmus\Letm1, Mmus\Letm2" "Hsap\LETM1, Hsap\LETM2" "partially lethal - majority die,some die during pupal stage,lethal - all die before end of P-stage,locomotor behavior defective,viable,neurophysiology defective,lethal - all die during first instar larval stage,lethal - all die before end of larval stage,lethal,some die during P-stage,small body,flightless,visible" "eye,eye disc,ommatidium | third instar larval stage,photoreceptor cell | third instar larval stage,mitochondrioney.PH,embryonic/larval neuromuscular junction" FBgn0025807 Rad9 Rad9 http://flybase.org/reports/FBgn0025807 - protein_coding_gene 3'-5' exonuclease activity ; GO:0008408 | inferred from biological aspect of ancestor with PANTHER:PTN000391242 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W157 intra-S DNA damage checkpoint ; GO:0031573 | inferred from biological aspect of ancestor with PANTHER:PTN000391242 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000391242 nucleic acid phosphodiester bond hydrolysis ; GO:0090305 | inferred from biological aspect of ancestor with PANTHER:PTN000391242 DNA replication checkpoint ; GO:0000076 | inferred from biological aspect of ancestor with PANTHER:PTN000391242 cellular response to ionizing radiation ; GO:0071479 | inferred from biological aspect of ancestor with PANTHER:PTN000391242 nucleus ; GO:0005634 | inferred from direct assay checkpoint clamp complex ; GO:0030896 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay "CG3945, Rad9, rad9, DmRad9" "IPR007268:Rad9/Ddc1, IPR026584:Rad9" CG3945 11-Aug-17 DroID_v2017_08 "Drer\rad9a, Drer\rad9b" Scer\DDC1 Cele\hpr-9 "Xtro\rad9b, Xtro\rad9a" "Mmus\Rad9a, Mmus\Rad9b" "Hsap\RAD9B, Hsap\RAD9A" "viable,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039486 caix caix http://flybase.org/reports/FBgn0039486 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from electronic annotation with InterPro:IPR018338 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR018338 - "CT19053, caix, CAIX, CG6074" "IPR001148:Alpha carbonic anhydrase, IPR018338:Carbonic anhydrase, alpha-class, conserved site, IPR023561:Carbonic anhydrase, alpha-class" CG6074 11-Aug-17 DroID_v2017_08 "Drer\ptprga, Drer\ca16b, Drer\ca4c, Drer\car15, Drer\ca6, Drer\ca15a, Drer\ca2, Drer\zgc:153760, Drer\ca7, Drer\ca5a, Drer\ca14, Drer\ca4a, Drer\si:ch211-173d10.4, Drer\ca10b, Drer\ca10a, Drer\ca8, Drer\ca15b, Drer\ca9, Drer\cahz, Drer\ca12, Drer\ca4b, Drer\ca15c" - "Cele\cah-5, Cele\cah-4, Cele\cah-6, Cele\cah-3" "Xtro\ca11, Xtro\ca14, Xtro\ca12, Xtro\ca10, Xtro\LOC779564, Xtro\ca3, Xtro\ca2, Xtro\ca5b, Xtro\ca1, Xtro\ca4, Xtro\ca8, Xtro\ca6, Xtro\ca7" "Mmus\Car14, Mmus\Car15, Mmus\Car6, Mmus\Car7, Mmus\Car12, Mmus\Car5a, Mmus\Car10, Mmus\Car9, Mmus\Car5b, Mmus\Car2, Mmus\Car11, Mmus\Car4, Mmus\Car3, Mmus\Car13, Mmus\Car8, Mmus\Ptprg, Mmus\Car1" "Hsap\CA10, Hsap\CA13, Hsap\CA4, Hsap\CA8, Hsap\CA14, Hsap\PTPRG, Hsap\CA2, Hsap\CA5A, Hsap\CA9, Hsap\CA1, Hsap\CA5B, Hsap\CA12, Hsap\CA7, Hsap\CA11, Hsap\CA6, Hsap\CA3" "lethal,viable" FBgn0000048 ad arcoid http://flybase.org/reports/FBgn0000048 - gene - - - ad - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "wing,crossvein,leg,mesothoracic suture" FBgn0002239 l(3)68Ca lethal (3) 68Ca http://flybase.org/reports/FBgn0002239 - gene - - - "l(3)v4-2, l(3)68Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,heat sensitive" FBgn0267610 CR45948 - http://flybase.org/reports/FBgn0267610 pseudogene_attribute - - - CR45948 - CR45948 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040660 CG13551 - http://flybase.org/reports/FBgn0040660 protein_coding_gene ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 ATPase inhibitor activity ; GO:0042030 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 negative regulation of ATPase activity ; GO:0032780 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000601269 "BcDNA:RE33866, CG13551, SK[[66]]" IPR007648:Mitochondrial ATPase inhibitor CG13551 11-Aug-17 DroID_v2017_08 "Drer\atpif1b, Drer\atpif1a" - "Cele\mai-2, Cele\mai-1" Xtro\atpif1 Mmus\Atpif1 Hsap\ATPIF1 viable FBgn0013385 acj9 abnormal-chemosensory-jump-9 http://flybase.org/reports/FBgn0013385 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,recessive" FBgn0259292 EP-603 - http://flybase.org/reports/FBgn0259292 gene - - - EP-603 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0025932 hip34 hb-interacting protein 34 http://flybase.org/reports/FBgn0025932 - gene - - - hip34 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046659 anon-38C.50 anon-38C.50 http://flybase.org/reports/FBgn0046659 gene - - - "38C.50, anon-38C.50" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266538 CG45099 - http://flybase.org/reports/FBgn0266538 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45099, CG6015-5'utr" - CG45099 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000958 fs(2)E5 female sterile (2) E5 http://flybase.org/reports/FBgn0000958 - gene - - - "fs2.5, fs(2)E5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female semi-sterile,recessive,female sterile" egg FBgn0000589 E(SD) Enhancer of Segregation Distorter http://flybase.org/reports/FBgn0000589 - gene - - - "E(Sd), E(SD)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040602 CG14545 - http://flybase.org/reports/FBgn0040602 protein_coding_gene - - - "BcDNA:RE55691, CG14545" - CG14545 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265685 CR44492 - http://flybase.org/reports/FBgn0265685 non_protein_coding_gene - - - CR44492 - CR44492 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003379 short-winged short winged http://flybase.org/reports/FBgn0003379 - gene - - - "short-winged, sh" - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0003687 Tbp TATA binding protein http://flybase.org/reports/FBgn0003687 "FBgn0013961, FBtr0071679, FBpp0071596" protein_coding_gene "transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf105 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay RNA polymerase III transcription factor activity, sequence-specific DNA binding ; GO:0001034 | inferred from sequence or structural similarity with UniProtKB:P20226 chromatin binding ; GO:0003682 | inferred from direct assay transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay TFIIA-class transcription factor binding ; GO:0001092 | inferred from physical interaction with TfIIA-L transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf1 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly ; GO:0001129 | inferred from physical interaction with Taf12 core promoter binding ; GO:0001047 | inferred from direct assay RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with mbf1" "snRNA transcription from RNA polymerase III promoter ; GO:0042796 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of ribosomal protein gene transcription from RNA polymerase II promoter ; GO:0060962 | NOT inferred from direct assay inferred from mutant phenotype positive regulation of transcription initiation from RNA polymerase II promoter ; GO:0060261 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement tRNA transcription from RNA polymerase III promoter ; GO:0042797 | inferred from direct assay inferred from mutant phenotype tRNA transcription from RNA polymerase III promoter ; GO:0042797 | inferred from direct assay RNA polymerase II transcriptional preinitiation complex assembly ; GO:0051123 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from direct assay DNA-templated transcription, initiation ; GO:0006352 | inferred from direct assay regulation of transcription from RNA polymerase III promoter ; GO:0006359 | inferred from mutant phenotype" "transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11588 inferred from sequence or structural similarity with SGD:S000000950 transcription factor TFIID complex ; GO:0005669 | inferred from physical interaction with Taf4 inferred from physical interaction with Taf6 nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIIIB complex ; GO:0000126 | colocalizes_with inferred from physical interaction with Taf105 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred by curator from GO:0006359,GO:0042796,GO:0042797" "Tbp, TBP, dTBP, RBP, TFIID, CG9874, TBP38, TfIID, dTbp, TFIIDtau, dTFIID, dtbp" "IPR000814:TATA-box binding protein, IPR030491:TATA-box binding protein, conserved site, IPR033710:TATA-box binding protein, eukaryotic" CG9874 11-Aug-17 DroID_v2017_08 "Drer\tbpl2, Drer\tbp, Drer\tbpl1" Scer\SPT15 Cele\tbp-1 "Xtro\tbp, Xtro\tbpl2, Xtro\tbpl1" "Mmus\Tbpl2, Mmus\Tbpl1, Mmus\Tbp" "Hsap\TBP, Hsap\TBPL2, Hsap\TBPL1" embryonic stage "lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage" DRSC23111 K -0.84123306 1.361228404 0.100177131 1.249869573 1.202017971 4.542892511 FBgn0259935 CG42458 - http://flybase.org/reports/FBgn0259935 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000359713 "CG42458, CG33277, CG18656, cg18656, CG33279" "IPR000504:RNA recognition motif domain, IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG42458 11-Aug-17 DroID_v2017_08 "Drer\eif4h, Drer\si:dkey-234i14.2, Drer\dazl, Drer\cirbpa, Drer\zgc:55733, Drer\trnau1apa, Drer\srsf10a, Drer\hnrnpc, Drer\hnrnpa1b, Drer\zcrb1, Drer\hnrnpaba, Drer\ncoa5, Drer\wu:fq32h04, Drer\eif4ba, Drer\hnrnpd, Drer\trnau1apb, Drer\rbm34, Drer\hnrnpabb, Drer\hnrnpa3, Drer\raly" "Scer\NOP6, Scer\CWC2, Scer\NGR1, Scer\MUD1, Scer\NAB6, Scer\NAM8, Scer\NOP12, Scer\MRN1, Scer\NAB3" "Cele\C50F2.2, Cele\ztf-4" "Xtro\dazl, Xtro\hnrnpab, Xtro\cirbp, Xtro\hnrnpc, Xtro\eif4h, Xtro\hnrnpa2b1, Xtro\hnrnpa3, Xtro\ralyl, Xtro\rbm34, Xtro\hnrnpa1, Xtro\trnau1ap, Xtro\hnrnpd, Xtro\eif4b, Xtro\hnrnpdl, Xtro\raly" "Mmus\Gm21379, Mmus\Trnau1ap, Mmus\Rbm34, Mmus\Boll, Mmus\Srsf12, Mmus\Hnrnpa2b1, Mmus\Eif4h, Mmus\Hnrnpab, Mmus\Hnrnpa3, Mmus\Srsf10, Mmus\Hnrnpa1, Mmus\Raly, Mmus\Slirp, Mmus\Ralyl, Mmus\Eif4b, Mmus\Zcrb1, Mmus\Cirbp, Mmus\Hnrnpc, Mmus\Tra2b, Mmus\Rbm31y, Mmus\Dazl, Mmus\Hnrnpd" "Hsap\EIF4H, Hsap\RALYL, Hsap\RBM34, Hsap\HNRNPA2B1, Hsap\HNRNPCL4, Hsap\HNRNPD, Hsap\HNRNPA1L2, Hsap\RALY, Hsap\HNRNPA1, Hsap\HNRNPCL3, Hsap\CIRBP, Hsap\TRNAU1AP, Hsap\SLIRP, Hsap\DAZ3, Hsap\DAZ2, Hsap\EIF4B, Hsap\DAZ1, Hsap\DAZ4, Hsap\RBM3, Hsap\DAZL, Hsap\HNRNPCL1, Hsap\HNRNPCL2, Hsap\HNRNPA3, Hsap\SRSF10, Hsap\HNRNPAB, Hsap\BOLL, Hsap\HNRNPC" FBgn0028955 CG8788 - http://flybase.org/reports/FBgn0028955 protein_coding_gene - - - "BEST:HL05962, n(2)k04512, CG8788" - CG8788 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" eye FBgn0267674 CR46010 - http://flybase.org/reports/FBgn0267674 non_protein_coding_gene - - - CR46010 - CR46010 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035677 CG13293 - http://flybase.org/reports/FBgn0035677 protein_coding_gene transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN000478524 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR016607, InterPro:IPR022709" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000478524 CG13293 "IPR022709:Protein SCAI, IPR016607:Protein SCAI, metazoan/viridiplantae" CG13293 11-Aug-17 DroID_v2017_08 Drer\scai "Scer\NUP42, Scer\NUP159" - Xtro\scai Mmus\Scai Hsap\SCAI viable FBgn0267797 CR46122 - http://flybase.org/reports/FBgn0267797 non_protein_coding_gene - - - CR46122 - CR46122 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032946 nrv3 nervana 3 http://flybase.org/reports/FBgn0032946 protein_coding_gene - potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR000402 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR000402 response to auditory stimulus ; GO:0010996 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred from electronic annotation with InterPro:IPR000402 plasma membrane ; GO:0005886 | inferred from direct assay "CG8663, JYbeta1, Nrv3, nrv3, nervana3" IPR000402:Sodium/potassium-transporting ATPase subunit beta CG8663 11-Aug-17 DroID_v2017_08 "Drer\atp1b4, Drer\atp1b1a, Drer\atp1b2b, Drer\atp1b1b, Drer\atp1b3a, Drer\atp1b3b, Drer\atp1b2a" - "Cele\nkb-1, Cele\nkb-2, Cele\nkb-3" "Xtro\atp1b4, Xtro\atp1b3, Xtro\atp1b2, Xtro\atp1b1, Xtro\atp4b" "Mmus\Atp4b, Mmus\Atp1b4, Mmus\Atp1b1, Mmus\Atp1b2, Mmus\Atp1b3" "Hsap\ATP1B2, Hsap\ATP1B1, Hsap\ATP4B, Hsap\ATP1B4, Hsap\ATP1B3" "neurophysiology defective,conditional,stress response defective,lethal,viable,auditory perception defective,long lived,starvation stress response defective,male limited,temperature response defective" "mitochondrion,mitochondrion | conditional" FBgn0039462 CG14252 - http://flybase.org/reports/FBgn0039462 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG14252 IPR026095:Myb/SANT-like DNA-binding domain-containing protein CG14252 11-Aug-17 DroID_v2017_08 Drer\msantd1 - - - Mmus\Msantd1 Hsap\MSANTD1 viable FBgn0038455 CG14907 - http://flybase.org/reports/FBgn0038455 protein_coding_gene - - - CG14907 - CG14907 11-Aug-17 DroID_v2017_08 - - Cele\pdi-3 - - - DRSC15027 I 1.764272474 -0.543241323 0.342964934 0.020909302 0.340427147 0.343910865 FBgn0030853 ND-24 NADH dehydrogenase (ubiquinone) 24 kDa subunit http://flybase.org/reports/FBgn0030853 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from biological aspect of ancestor with PANTHER:PTN000042665 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P19404 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from biological aspect of ancestor with PANTHER:PTN000042666 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P19404" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000042666 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P19404 "CG5703, BEST:LP01573, CG 5703, NUHM, ND-24, Ndufv2" "IPR002023:NADH-quinone oxidoreductase subunit E-like, IPR012336:Thioredoxin-like fold" CG5703 11-Aug-17 DroID_v2017_08 Drer\ndufv2 - Cele\F53F4.10 Xtro\ndufv2 Mmus\Ndufv2 Hsap\NDUFV2 "viable,visible" trichogen cell FBgn0015508 lali lali http://flybase.org/reports/FBgn0015508 - gene - "terminal branching, open tracheal system ; GO:0007430 | traceable author statement" - lali - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266436 CG45066 - http://flybase.org/reports/FBgn0266436 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45066, CG14955" - CG45066 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020268 mus115 mus115 http://flybase.org/reports/FBgn0020268 - gene - - - mus115 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0005158 l(2)G137 lethal (2) G137 http://flybase.org/reports/FBgn0005158 - gene - - - l(2)G137 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052083 CG32083 - http://flybase.org/reports/FBgn0052083 protein_coding_gene - - - CG32083 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262651 l(2)47A9-6 lethal (2) 47A9-6 http://flybase.org/reports/FBgn0262651 gene - - - l(2)47A9-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082349 HM400 HM400 http://flybase.org/reports/FBgn0082349 gene - - - HM400 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038919 CG17843 - http://flybase.org/reports/FBgn0038919 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from sequence or structural similarity with HGNC:9756 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR017905 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 extracellular space ; GO:0005615 | inferred from sequence model "anon-WO0140519.66, CG17843, DmQSOX2, Erv1" "IPR012336:Thioredoxin-like fold, IPR017905:ERV/ALR sulfhydryl oxidase domain, IPR013766:Thioredoxin domain" CG17843 11-Aug-17 DroID_v2017_08 "Drer\qsox1, Drer\qsox2" - "Cele\T10H10.2, Cele\F35G2.1, Cele\F47B7.2" "Xtro\qsox1, Xtro\qsox2" "Mmus\Qsox2, Mmus\Qsox1" "Hsap\QSOX1, Hsap\QSOX2" FBgn0002505 l(3)SG66 lethal (3) SG66 http://flybase.org/reports/FBgn0002505 FBgn0004731 gene - - - "l(3)ds-3, l(3)g60A, l(3)g60R, l(3)ds3, l(3)B3, G60A, B3, l(3)SG66" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0035582 CG13705 - http://flybase.org/reports/FBgn0035582 protein_coding_gene - - - "CG13705, CG13705-PA" "IPR004011:GYR motif, IPR004019:YLP motif" CG13705 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051601 CG31601 - http://flybase.org/reports/FBgn0051601 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31601 "IPR000571:Zinc finger, CCCH-type" CG31601 11-Aug-17 DroID_v2017_08 "Drer\zc3h18, Drer\ppp1r10" - - - "Mmus\Zc3h18, Mmus\Ppp1r10, Mmus\Prr3" "Hsap\ZC3H18, Hsap\PRR3, Hsap\PPP1R10" viable FBgn0030998 CG14195 - http://flybase.org/reports/FBgn0030998 protein_coding_gene - - - CG14195 IPR020846:Major facilitator superfamily domain CG14195 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" trichogen cell FBgn0266319 CR44984 - http://flybase.org/reports/FBgn0266319 non_protein_coding_gene - - - CR44984 - CR44984 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039930 CG11077 - http://flybase.org/reports/FBgn0039930 protein_coding_gene - mitochondrial genome maintenance ; GO:0000002 | inferred from sequence or structural similarity with UniProtKB:P39210 homeostatic process ; GO:0042592 | inferred from sequence or structural similarity with UniProtKB:P39210 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:9716 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:P39210 CG11077 IPR007248:Mpv17/PMP22 CG11077 11-Aug-17 DroID_v2017_08 "Drer\mpv17l2, Drer\mpv17, Drer\pxmp2, Drer\si:ch211-120k19.1" "Scer\YOR292C, Scer\SYM1" "Cele\T18D3.9, Cele\ZK470.1" "Xtro\pxmp2, Xtro\mpv17l2" "Mmus\Mpv17, Mmus\Pxmp2, Mmus\Mpv17l, Mmus\Mpv17l2" "Hsap\MPV17, Hsap\PXMP2, Hsap\MPV17L2, Hsap\MPV17L" "viable,fertile" FBgn0001353 l(1)1EFb lethal (1) 1EFb http://flybase.org/reports/FBgn0001353 - gene - - - "l(1)BA2, l(1)1EFb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037873 SdhC "Succinate dehydrogenase, subunit C" http://flybase.org/reports/FBgn0037873 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR018495 succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from sequence or structural similarity with UniProtKB:Q99643 "determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from mutant phenotype tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:Q99643 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype" "mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from sequence or structural similarity with UniProtKB:Q99643" "BcDNA:RH04289, sdhC, SdhC, CG6666, SDH, RH04289p, C560" "IPR000701:Succinate dehydrogenase/Fumarate reductase, transmembrane subunit, IPR018495:Succinate dehydrogenase, cytochrome b subunit, conserved site, IPR014314:Succinate dehydrogenase, cytochrome b556 subunit" CG6666 11-Aug-17 DroID_v2017_08 Drer\sdhc "Scer\SDH3, Scer\SHH3" Cele\mev-1 Xtro\sdhc Mmus\Sdhc Hsap\SDHC "viable,visible,short lived,drug conditional" trichogen cell FBgn0262165 Z2528 - http://flybase.org/reports/FBgn0262165 gene - - - Z2528 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable photoreceptor cell R7 FBgn0267515 28SrRNA-Psi:CR45855 28S ribosomal RNA pseudogene:CR45855 http://flybase.org/reports/FBgn0267515 pseudogene_attribute - - - "CR45855, 28SrRNA-Psi:CR45855" - CR45855 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023150 Su(mg)3-2 Suppressor of modifier of gypsy 3-2 http://flybase.org/reports/FBgn0023150 - gene - - - Su(mg)3-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065311 l(2)SH1949 lethal (2) SH1949 http://flybase.org/reports/FBgn0065311 gene - - - "l(2)SH1949, l(2)SH2 1949" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086073 snoRNA:Me18S-A1494 - http://flybase.org/reports/FBgn0086073 snoRNA_gene - - - "snoRNA:Me18S-A1494, Me18S-Am1494, CR34702" - CR34702 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259358 C639.1 - http://flybase.org/reports/FBgn0259358 gene - - - C639.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing hair,wing margin,chaeta,ectopic" FBgn0266150 CR44856 - http://flybase.org/reports/FBgn0266150 non_protein_coding_gene - - - CR44856 - CR44856 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265959 rdgC retinal degeneration C http://flybase.org/reports/FBgn0265959 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity calcium-dependent protein serine/threonine phosphatase activity ; GO:0004723 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000003355 calmodulin binding ; GO:0005516 | inferred from direct assay inferred from physical interaction with Cam phototransduction ; GO:0007602 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement phototransduction ; GO:0007602 | traceable author statement protein dephosphorylation ; GO:0006470 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity thermotaxis ; GO:0043052 | inferred from direct assay deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype calcium-mediated signaling ; GO:0019722 | traceable author statement nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000003355 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003355 "CG6571, rdgC, CG44746, RDGC, DmrdgC-77B, RDGC/PP5, RdgC 77B, RdgC, CG13814" "IPR029052:Metallo-dependent phosphatase-like, IPR018247:EF-Hand 1, calcium-binding site, IPR000048:IQ motif, EF-hand binding site, IPR002048:EF-hand domain, IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR011992:EF-hand domain pair" CG44746 11-Aug-17 DroID_v2017_08 "Drer\ppef2a, Drer\ppef2b, Drer\ppef1" "Scer\PPG1, Scer\PPT1" "Cele\C34D4.2, Cele\F25B3.4, Cele\pef-1, Cele\ZK354.9" "Xtro\ppef2, Xtro\ppef1" "Mmus\Ppef1, Mmus\Ppef2" "Hsap\PPEF2, Hsap\PPEF1" adult stage " ocellus

, mushroom body

, retina

" FBgn0000033 AcpJ Accessory gland protein I http://flybase.org/reports/FBgn0000033 - gene - - - "AcpI, AcpJ" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010068 M(3)54c M(3)54c http://flybase.org/reports/FBgn0010068 - gene - - - M(3)54c - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013252 E(var)3-6 E(var)3-6 http://flybase.org/reports/FBgn0013252 - gene - - - "E-var(3)6, E(var)3-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0060852 l(3)S048414 lethal (3) S048414 http://flybase.org/reports/FBgn0060852 gene - - - "0484/14, l(3)S048414" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0262690 CR43160 - http://flybase.org/reports/FBgn0262690 non_protein_coding_gene - - - CR43160 - CR43160 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026879 CG13364 - http://flybase.org/reports/FBgn0026879 "FBgn0027685, FBgn0042219" protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "EG:115C2.12, CG18451, anon-EST:Posey36, CG13364" IPR015157:Translation machinery associated TMA7 CG13364 11-Aug-17 DroID_v2017_08 Drer\tma7 Scer\TMA7 Cele\F49C12.11 Xtro\tma7 Mmus\Tma7 Hsap\TMA7 "viable,body color defective" mesothoracic tergum FBgn0028504 CG12182 - http://flybase.org/reports/FBgn0028504 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GH02340, CG12182" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG12182 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,viable" "embryonic/larval brain,trichogen cell" FBgn0021956 l(2)k10217 lethal (2) k10217 http://flybase.net/reports/FBgn0021956.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0022319 l(1)B74.4 lethal (1) B74.4 http://flybase.org/reports/FBgn0022319 - gene - - - "B74.4, l(1)B74.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000723 FER FER tyrosine kinase http://flybase.org/reports/FBgn0000723 FBgn0022798 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 phospholipid binding ; GO:0005543 | inferred from sequence model protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement" "actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 dorsal closure ; GO:0007391 | inferred from genetic interaction with Src42A transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 axon guidance ; GO:0007411 | inferred from mutant phenotype cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 cell migration ; GO:0016477 | inferred from biological aspect of ancestor with PANTHER:PTN001231165 regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein phosphorylation ; GO:0006468 | non-traceable author statement dorsal closure, elongation of leading edge cells ; GO:0007394 | inferred from mutant phenotype" extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 extrinsic component of membrane ; GO:0019898 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "FER, CG8874, Dfer, fer, DFER, FPS, DmHD-179, dfps 85D, dFer, Dfps, DFer, Dm FPS, Fer, dfps85D, fps, dfps, fps85D, HD-179, FpS95D, dfer, Fps85D" "IPR000719:Protein kinase domain, IPR000980:SH2 domain, IPR001060:FCH domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR016250:Tyrosine-protein kinase, Fes/Fps type, IPR031160:F-BAR domain" CG8874 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-206d17.1, Drer\fer, Drer\fes" - "Cele\ZC581.7, Cele\kin-5, Cele\spe-8, Cele\kin-21, Cele\F26E4.5, Cele\W03A5.1, Cele\W01B6.5, Cele\T06C10.3, Cele\C25A8.5, Cele\C34F11.5, Cele\C18H7.4, Cele\T25B9.5, Cele\Y43C5B.2, Cele\kin-6, Cele\F57B9.8, Cele\T21G5.1, Cele\C35E7.10, Cele\kin-24, Cele\kin-14, Cele\R11E3.1, Cele\Y52D5A.2, Cele\frk-1, Cele\F59A3.8, Cele\R05H5.4, Cele\C55C3.4, Cele\kin-26, Cele\Y69E1A.3, Cele\F22B3.8, Cele\ZK622.1, Cele\F23C8.7, Cele\Y116A8C.38, Cele\Y116A8C.24, Cele\T25B9.4, Cele\K09B11.5" "Xtro\fer, Xtro\fes, Xtro\LOC100490493" "Mmus\Styk1, Mmus\Fes, Mmus\Fer" "Hsap\STYK1, Hsap\FER, Hsap\FES" "viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage" "ventral midline,dorsal closure embryo,embryonic leading edge cell & actomyosin,embryonic leading edge cell & filopodium,amnioserosa" DRSC12735 I -0.017009542 1.743626174 -0.240289491 0.085946582 0.771491588 -0.716545839 FBgn0041762 centrin centrin http://flybase.org/reports/FBgn0041762 gene - - - centrin - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015860 anon-1Aa anon-1Aa http://flybase.org/reports/FBgn0015860 - gene - - - anon-1Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035283 CG12024 - http://flybase.org/reports/FBgn0035283 protein_coding_gene - - - CG12024 "IPR003892:Ubiquitin system component Cue, IPR009060:UBA-like" CG12024 11-Aug-17 DroID_v2017_08 "Drer\cuedc1a, Drer\cuedc1b" - Cele\F43C1.5 Xtro\cuedc1 Mmus\Cuedc1 Hsap\CUEDC1 viable DRSC08229 I 0.136445136 1.737151494 -0.636549596 0.198226456 0.201711501 1.234143185 FBgn0065871 l(2)SH0256 lethal (2) SH0256 http://flybase.org/reports/FBgn0065871 gene - - - l(2)SH0256 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028624 l(2)04207a lethal (2) 04207a http://flybase.org/reports/FBgn0028624 gene - - - "l(2)04207, l(2)04207a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001000 Fs(2)Tek Female sterile (2) Tekele http://flybase.org/reports/FBgn0001000 - gene - - - "Tek, Fs(2)Sz10, Fs(2)Tek" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,dominant" "embryo,cleavage nucleus" FBgn0053374 5SrRNA:CR33374 5SrRNA:CR33374 http://flybase.org/reports/FBgn0053374 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33374, 5SrRNA:CR33374" - CR33374 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066321 zol zolotistuy http://flybase.org/reports/FBgn0066321 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available zol - - 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,chemical sensitive" FBgn0032243 Klp31E Kinesin-like protein at 31E http://flybase.org/reports/FBgn0032243 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 "DmKlp31E, DmKlp31D, DmCG5300, CG5300, Klp31E, KLP31E, KIF 21A, KIF21A/B" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019821:Kinesin motor domain, conserved site" CG5300 11-Aug-17 DroID_v2017_08 "Drer\kif4, Drer\kif21a, Drer\kif21b, Drer\LOC100149074, Drer\kif7" Scer\KIP3 Cele\klp-12 "Xtro\kif7, Xtro\kif4a, Xtro\kif27, Xtro\kif21a, Xtro\kif21b" "Mmus\Kif4, Mmus\Kif27, Mmus\Kif7, Mmus\Kif21a, Mmus\Kif21b" "Hsap\KIF21B, Hsap\KIF7, Hsap\KIF4A, Hsap\KIF4B, Hsap\KIF21A, Hsap\KIF27" viable FBgn0010226 GstS1 Glutathione S transferase S1 http://flybase.org/reports/FBgn0010226 "FBgn0010568, FBgn0022031" protein_coding_gene glutathione peroxidase activity ; GO:0004602 | inferred from direct assay glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione transferase activity ; GO:0004364 | non-traceable author statement glutathione metabolic process ; GO:0006749 | inferred from direct assay metabolic process ; GO:0008152 | inferred by curator from GO:0004364 response to oxidative stress ; GO:0006979 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "Gst2, CG8938, GST-2, DmGSTS1-1, DmGST2, GSTS1, GST S1, DmGST-2, DmGSTS1, GST2, l(2)k08805, l(2)04227, n(2)06253, Est2, GSTII, DmGst-2, GST, gstD2, GstS1, GstS1-1, DmGstS1-1, gsts1, S1, lincRNA.330" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG8938 11-Aug-17 DroID_v2017_08 "Drer\gstp2, Drer\gstp1, Drer\gsta.2, Drer\gstm.3, Drer\gsta3, Drer\gstm.2, Drer\gsta.1" - "Cele\gst-37, Cele\gst-17, Cele\gst-9, Cele\gst-2, Cele\gst-5, Cele\gst-16, Cele\gst-18, Cele\gst-7, Cele\gst-28, Cele\gst-20, Cele\F55A11.6, Cele\gst-19, Cele\gst-39, Cele\gst-30, Cele\gst-27, Cele\gst-24, Cele\gst-14, Cele\gst-36, Cele\gst-21, Cele\gst-31, Cele\gst-40, Cele\gst-29, Cele\gst-11, Cele\gst-12, Cele\gst-33, Cele\gst-13, Cele\gst-3, Cele\gst-35, Cele\gst-6, Cele\gst-4, Cele\gst-8, Cele\gst-22, Cele\gst-15, Cele\gst-26, Cele\gst-32, Cele\gst-34, Cele\gst-38" "Xtro\gstm1, Xtro\hpgds" "Mmus\Gsta3, Mmus\Gstm4, Mmus\Gm10639, Mmus\Gstm2, Mmus\Hpgds, Mmus\Gsta2, Mmus\Gsta1, Mmus\Gsta4" "Hsap\GSTA1, Hsap\HPGDS, Hsap\GSTM4, Hsap\GSTA3, Hsap\GSTM1, Hsap\GSTA2, Hsap\GSTA4, Hsap\GSTA5" embryonic stage -- adult stage "viable,lethal,recessive,fertile,visible,wild-type,partially lethal - majority live,male sterile" "embryonic/larval hemocyte | third instar larval stage,macrochaeta,wing,eye" FBgn0016979 snRNA:K9 small nuclear RNA K9 http://flybase.org/reports/FBgn0016979 - snRNA_gene - - - "K9, snRNA:K9" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001810 l(1)mt lethal (1) mt http://flybase.org/reports/FBgn0001810 - gene - - - l(1)mt - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0003365 sesH stress-sensitive H http://flybase.org/reports/FBgn0003365 - gene - - - sesH - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001891 l(2)21De lethal (2) 21De http://flybase.org/reports/FBgn0001891 - gene - - - "l(2)neh-5, l(2)neh5, l(2)21De" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265203 CR44263 - http://flybase.org/reports/FBgn0265203 non_protein_coding_gene - - - "CR44263, lincRNA.917" - CR44263 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035166 CG13902 - http://flybase.org/reports/FBgn0035166 protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with HGNC:25840 G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from sequence or structural similarity with HGNC:25840 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:25840 CG13902 IPR003347:JmjC domain CG13902 11-Aug-17 DroID_v2017_08 "Drer\kdm8, Drer\hif1an, Drer\tyw5, Drer\hspbap1" - Cele\jmjd-5 "Xtro\hspbap1, Xtro\kdm8, Xtro\hif1an" "Mmus\Kdm8, Mmus\Hif1an, Mmus\Hspbap1, Mmus\Tyw5" "Hsap\KDM8, Hsap\HSPBAP1, Hsap\HIF1AN, Hsap\TYW5" "viable,fertile" FBgn0044390 Scim4 Sensitized chromosome inheritance modifier 4 http://flybase.org/reports/FBgn0044390 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0050352 CG30352 - http://flybase.org/reports/FBgn0050352 protein_coding_gene - - - CG30352 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012017 tRNA:Tyr-GTA-1-2 transfer RNA:Tyrosine-GTA 1-2 http://flybase.org/reports/FBgn0012017 "FBgn0003842, FBgn0012014, FBgn0051986, FBgn0060007" tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "tRNA-Tyr, tRNA[Tyr], tRNA[Tyr][[1gamma]], AE002638.trna3-TyrGTA, tRNA:Y, tRNA:Y:GTA:AE002638-a, CR31986, tRNA:tyr1:22Fb, chr2L.trna36-TyrGTA, tRNA-Tyr-GTA-1-2, tRNA:Tyr-GTA-1-2, tRNA:Y1:22Fb, UAC" - CR31986 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037987 CG14739 - http://flybase.org/reports/FBgn0037987 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with SGD:S000000738 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000630520 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000738 CG14739 "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG14739 11-Aug-17 DroID_v2017_08 Drer\ube2h Scer\UBC8 Cele\ubc-8 Xtro\ube2h Mmus\Ube2h Hsap\UBE2H viable FBgn0001989 ND-B17 NADH dehydrogenase (ubiquinone) B17 subunit http://flybase.org/reports/FBgn0001989 "FBgn0028508, FBgn0064934" protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95139 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95139" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95139 "BG:DS09217.1, CG13240, BcDNA:GM23292, l(2)35Di, NB7M, ND-B17" "IPR019174:NADH dehydrogenase 1, beta subcomplex, subunit 6" CG13240 11-Aug-17 DroID_v2017_08 Drer\ndufb6 - Cele\ZK809.3 Xtro\ndufb6 Mmus\Ndufb6 Hsap\NDUFB6 "male sterile,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,viable,visible" "wing,trichogen cell" FBgn0005423 l(1)adl12 lethal (1) adl12 http://flybase.org/reports/FBgn0005423 - gene - - - "l(1)adl-12, l(1)adl12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,heat sensitive,lethal,partially lethal - majority die" FBgn0051958 CR31958 - http://flybase.org/reports/FBgn0051958 pseudogene_attribute calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "CG10022, CG31958, CR31958" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CR31958 11-Aug-17 DroID_v2017_08 "Drer\calml4a, Drer\pvalb6, Drer\pvalb2, Drer\tnnc1b, Drer\pvalb8, Drer\pvalb3, Drer\cabp1a, Drer\cabp4, Drer\calm1b, Drer\cabp2b, Drer\cabp1b, Drer\tnnc2, Drer\calm1a, Drer\pvalb9, Drer\calm3b, Drer\calm2a, Drer\caln1, Drer\calm3a, Drer\cabp2a, Drer\pvalb4, Drer\cabp5a, Drer\tnnc1a, Drer\pvalb1, Drer\calb2b, Drer\efcab11, Drer\efcab6, Drer\calb2a, Drer\calm2b, Drer\calml4b, Drer\caln2, Drer\cabp7b, Drer\si:ch211-197n1.2, Drer\efcab2, Drer\rhbdl3, Drer\calb1, Drer\cabp5b, Drer\scgn" "Scer\CMD1, Scer\MLC1, Scer\MLC2" "Cele\cal-2, Cele\cmd-1, Cele\cal-1, Cele\cal-3, Cele\cal-4" "Xtro\efcab6, Xtro\calml4, Xtro\pvalb, Xtro\cabp4, Xtro\pvalb.2, Xtro\ocm.2, Xtro\cabp7, Xtro\tnnc2, Xtro\calm1, Xtro\pgm1, Xtro\pvalb.1, Xtro\LOC548651, Xtro\tnnc1, Xtro\calm2, Xtro\calb1, Xtro\ocm, Xtro\scgn" "Mmus\Calb1, Mmus\Cabp7, Mmus\1700023F06Rik, Mmus\Cabp1, Mmus\Cabp2, Mmus\Cabp5, Mmus\Cabp4, Mmus\Pvalb, Mmus\Efcab6, Mmus\Efcab2, Mmus\Efcab9, Mmus\Ocm, Mmus\Spata21, Mmus\Calm2, Mmus\Efcab11, Mmus\Tnnc2, Mmus\Calm3, Mmus\Rhbdl3, Mmus\Calm5, Mmus\Calm4, Mmus\Caln1, Mmus\Calml3, Mmus\Efcab7, Mmus\Tnnc1, Mmus\Calm1, Mmus\Efcab3, Mmus\Scgn, Mmus\Calb2, Mmus\Calml4" "Hsap\C2orf61, Hsap\SPATA21, Hsap\EFCAB7, Hsap\PVALB, Hsap\CABP2, Hsap\EFCAB13, Hsap\CALML6, Hsap\CABP1, Hsap\CABP7, Hsap\CALML4, Hsap\OCM, Hsap\CALM2, Hsap\OCM2, Hsap\RHBDL3, Hsap\CALB2, Hsap\EFCAB3, Hsap\CALM3, Hsap\TNNC2, Hsap\CABP4, Hsap\CALN1, Hsap\CALML5, Hsap\EFCAB2, Hsap\TNNC1, Hsap\SCGN, Hsap\CALB1, Hsap\EFCAB9, Hsap\CALM1, Hsap\CABP5, Hsap\CALML3, Hsap\EFCAB11, Hsap\EFCAB6" FBgn0035868 CG7194 - http://flybase.org/reports/FBgn0035868 protein_coding_gene molecular_function ; GO:0003674 | no biological data available copper ion homeostasis ; GO:0055070 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "ck00048, CK01174, BEST:CK00048, BEST:CK01174, CG7194" IPR024810:Mab-21 domain CG7194 11-Aug-17 DroID_v2017_08 Drer\mb21d1 - - - Mmus\Mb21d1 Hsap\MB21D1 viable FBgn0058354 CR40354 - http://flybase.org/reports/FBgn0058354 pseudogene_attribute - - - "CG40354, CR40354" - CR40354 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001823 l(1)tr lethal (1) tracheae ramified http://flybase.org/reports/FBgn0001823 - gene - - - l(1)tr - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" embryonic/larval tracheal system FBgn0051229 CG31229 - http://flybase.org/reports/FBgn0051229 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:Q9Y584 protein channel activity ; GO:0015266 | inferred from biological aspect of ancestor with PANTHER:PTN000364156 protein channel activity ; GO:0015266 | inferred from sequence or structural similarity with UniProtKB:Q12328 mitochondrion targeting sequence binding ; GO:0030943 | inferred from biological aspect of ancestor with PANTHER:PTN000364157 protein import into mitochondrial inner membrane ; GO:0045039 | inferred from biological aspect of ancestor with PANTHER:PTN000364157 protein import into mitochondrial inner membrane ; GO:0045039 | inferred from sequence or structural similarity with UniProtKB:Q12328 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q9Y584 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q9Y584 mitochondrial inner membrane protein insertion complex ; GO:0042721 | inferred from biological aspect of ancestor with PANTHER:PTN000364157 mitochondrial inner membrane protein insertion complex ; GO:0042721 | inferred from sequence or structural similarity with UniProtKB:Q12328 CG31229 IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG31229 11-Aug-17 DroID_v2017_08 Drer\timm22 Scer\TIM22 Cele\C47G2.3 Xtro\timm22 Mmus\Timm22 Hsap\TIMM22 "viable,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0263082 CG43350 - http://flybase.org/reports/FBgn0263082 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG43350, CG42845, Chr2L_9349524_9350014.0, lincRNA.88" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG43350 11-Aug-17 DroID_v2017_08 - - Cele\C34F6.1 - - - FBgn0033261 udd under-developed http://flybase.org/reports/FBgn0033261 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter ; GO:1901838 | inferred from mutant phenotype RNA polymerase transcription factor SL1 complex ; GO:0005668 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "CG18316, udd, Udd" - CG18316 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,recessive,decreased cell number,germline clone,progressive,lethal - all die before end of embryonic stage,viable,visible" "female germline stem cell,germline clone,progressive,trichogen cell" FBgn0030234 CG15211 - http://flybase.org/reports/FBgn0030234 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001103553 CG15211 IPR008253:Marvel domain CG15211 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-66d1.7, Drer\cmtm6, Drer\zgc:101772, Drer\pllp, Drer\mal2, Drer\cmtm7, Drer\myadml2, Drer\LOC101882154, Drer\LOC100536607, Drer\cmtm8a, Drer\plp2, Drer\marveld1, Drer\cmtm3, Drer\cmtm8b, Drer\zgc:158773, Drer\zgc:136605, Drer\cmtm4, Drer\LOC101882206" - "Cele\K09G1.1, Cele\F47B3.3, Cele\drr-1, Cele\F28H1.4" "Xtro\cmtm6, Xtro\pllp, Xtro\mal2, Xtro\myadm, Xtro\cmtm3, Xtro\cmtm4, Xtro\plp2, Xtro\mal, Xtro\cmtm7, Xtro\myadml2" "Mmus\Marveld1, Mmus\Cmtm8, Mmus\Cmtm7, Mmus\Cmtm2a, Mmus\Myadml2, Mmus\Cmtm4, Mmus\Cmtm6, Mmus\Cklf, Mmus\Mal, Mmus\Cmtm5, Mmus\Cmtm1, Mmus\Myadm, Mmus\Plp2, Mmus\Mal2, Mmus\Pllp, Mmus\Cmtm2b, Mmus\Cmtm3" "Hsap\CKLF, Hsap\CKLF-CMTM1, Hsap\CMTM3, Hsap\MAL, Hsap\CMTM2, Hsap\CMTM5, Hsap\PLP2, Hsap\MARVELD1, Hsap\CMTM7, Hsap\CMTM1, Hsap\CMTM8, Hsap\MYADML2, Hsap\MYADM, Hsap\CMTM4, Hsap\CMTM6, Hsap\PLLP" viable DRSC19657 I 1.012903768 2.075198594 0.143052709 0.582571327 0.08079973 -0.364468136 FBgn0026749 Yippee Yippee http://flybase.org/reports/FBgn0026749 "FBtr0073789, FBpp0073620" protein_coding_gene metal ion binding ; GO:0046872 | non-traceable author statement biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG1989, Yippee" "IPR004910:Yippee/Mis18/Cereblon, IPR034751:Yippee domain" CG1989 11-Aug-17 DroID_v2017_08 "Drer\ypel2a, Drer\ypel5, Drer\ypel3, Drer\ypel2b, Drer\ypel1" Scer\MOH1 "Cele\B0546.4, Cele\B0546.3, Cele\F37A8.5" "Xtro\ypel2, Xtro\ypel1, Xtro\ypel5" "Mmus\Ypel4, Mmus\Ypel5, Mmus\Ypel2, Mmus\Ypel3, Mmus\Ypel1" "Hsap\YPEL4, Hsap\YPEL1, Hsap\YPEL3, Hsap\YPEL2, Hsap\YPEL5" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0034567 CG15651 - http://flybase.org/reports/FBgn0034567 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein O-linked mannosylation ; GO:0035269 | inferred from sequence or structural similarity with HGNC:17997 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:17997 rough endoplasmic reticulum ; GO:0005791 | inferred from sequence or structural similarity with HGNC:17997 "CG15651, STT" - CG15651 11-Aug-17 DroID_v2017_08 Drer\fkrp - - Xtro\fkrp Mmus\Fkrp Hsap\FKRP viable FBgn0065645 l(2)SH0752 lethal (2) SH0752 http://flybase.org/reports/FBgn0065645 gene - - - "l(2)SH0752, l(2)SH2 0752" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267823 Gmer "GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase/4-reductase" http://flybase.org/reports/FBgn0267823 protein_coding_gene coenzyme binding ; GO:0050662 | inferred from electronic annotation with InterPro:IPR001509 GDP-L-fucose synthase activity ; GO:0050577 | inferred from direct assay GDP-L-fucose biosynthetic process ; GO:0042350 | inferred from direct assay dsRNA transport ; GO:0033227 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Gmer, CG3495, gmer, GER, DmGMER, l(2)SH1931" "IPR028614:GDP-L-fucose synthase/GDP-L-colitose synthase, IPR001509:NAD-dependent epimerase/dehydratase, IPR016040:NAD(P)-binding domain" CG3495 11-Aug-17 DroID_v2017_08 "Drer\tsta3, Drer\zgc:100864, Drer\zgc:110348" - Cele\ger-1 Xtro\tsta3 Mmus\Tsta3 Hsap\TSTA3 FBgn0067885 Mod(Prat:bw)1-2 Mod(Prat:bw)1-2 http://flybase.org/reports/FBgn0067885 gene - - - "Mod-1-2, Mod(Prat:bw)1-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001705 l(1)ESHS26 lethal (1) ESHS26 http://flybase.org/reports/FBgn0001705 - gene - - - l(1)ESHS26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040701 CG13714 - http://flybase.org/reports/FBgn0040701 protein_coding_gene - - - CG13714 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022081 l(2)k07526 lethal (2) k07526 http://flybase.org/reports/FBgn0022081 - gene - - - l(2)k07526 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004946 alarless alarless http://flybase.org/reports/FBgn0004946 - gene - - - "alr, alarless" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,good,fertile" "anterior postalar bristle,posterior supraalar bristle,notopleural bristle,humeral bristle,anterior scutellar bristle" FBgn0028141 l(3)S047431b lethal (3) S047431b http://flybase.org/reports/FBgn0028141 gene - - - "0474/31, l(3)S047431, l(3)S047431b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0030338 CG15741 - http://flybase.org/reports/FBgn0030338 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15741 - CG15741 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0086691 UK114 UK114 http://flybase.org/reports/FBgn0086691 protein_coding_gene - protein folding ; GO:0006457 | inferred from direct assay - "DUK114, DUK 114, CG15261, BG:DS07851.3, BcDNA:GM01181, UK114" "IPR013813:Endoribonuclease L-PSP/chorismate mutase-like, IPR006175:YjgF/YER057c/UK114 family, IPR006056:RidA family, IPR019897:RidA, conserved site" CG15261 11-Aug-17 DroID_v2017_08 Drer\hrsp12 "Scer\HMF1, Scer\MMF1, Scer\DPH6" Cele\C23G10.2 "Xtro\dph6, Xtro\hrsp12" Mmus\Rida Hsap\RIDA "partially lethal - majority die,visible" trichogen cell FBgn0034520 lms lateral muscles scarcer http://flybase.org/reports/FBgn0034520 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype" - "CG13424, lms" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR020479:Homeobox domain, metazoa" CG13424 11-Aug-17 DroID_v2017_08 "Drer\hmx1, Drer\hoxa13a, Drer\barhl1a, Drer\lbx2, Drer\hmx3a, Drer\hmx2, Drer\hmx4" Scer\PHO2 "Cele\ceh-22, Cele\ceh-19, Cele\duxl-1, Cele\ceh-45" "Xtro\hmx1, Xtro\nkx1-2, Xtro\nkx3-3, Xtro\hmx3, Xtro\hmx2, Xtro\hoxa3" "Mmus\Hmx3, Mmus\Hoxa3, Mmus\Hmx2, Mmus\Lhx1, Mmus\Gsc2, Mmus\Vax1, Mmus\Nkx2-9, Mmus\Hmx1, Mmus\Nkx3-1, Mmus\Isl2" "Hsap\HMX3, Hsap\HMX1, Hsap\VAX1, Hsap\HMX2, Hsap\NOTO, Hsap\LHX1" "viable,partially lethal - majority die,recessive,visible,flight defective" "A1-7 lateral transverse muscle,wing" FBgn0265826 CR44615 - http://flybase.org/reports/FBgn0265826 non_protein_coding_gene - - - CR44615 - CR44615 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033437 CG12926 - http://flybase.org/reports/FBgn0033437 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 CG12926 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG12926 11-Aug-17 DroID_v2017_08 "Drer\clvs2, Drer\ttpa, Drer\rlbp1a, Drer\ttpal, Drer\rlbp1b, Drer\sec14l7, Drer\sec14l8" "Scer\SFH5, Scer\YKL091C, Scer\SEC14" - "Xtro\rlbp1, Xtro\ttpal, Xtro\clvs1, Xtro\clvs2, Xtro\sec14l1, Xtro\mospd2, Xtro\sec14l3, Xtro\ttpa, Xtro\sec14l5" "Mmus\Ttpal, Mmus\Rlbp1, Mmus\Ttpa, Mmus\Sec14l5, Mmus\Sec14l2, Mmus\Sec14l4, Mmus\Clvs1, Mmus\Clvs2, Mmus\Sec14l3, Mmus\Sec14l1" "Hsap\SEC14L1, Hsap\CLVS2, Hsap\CLVS1, Hsap\SEC14L6, Hsap\TTPAL, Hsap\SEC14L2, Hsap\TTPA, Hsap\SEC14L4, Hsap\RLBP1, Hsap\SEC14L3, Hsap\SEC14L5" viable FBgn0069405 Jon99Co Jonah 99Co http://flybase.org/reports/FBgn0069405 gene - - - "Jon99Cbetao, Jon99C, JonC, Jon99Co" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003271 rol reduced optic lobes http://flybase.org/reports/FBgn0003271 - gene - - - rol - - 11-Aug-17 DroID_v2017_08 - - - - - - "optomotor response defective,neuroanatomy defective,neurophysiology defective,visual behavior defective" "optic lobe,lobula plate,lobula" FBgn0011970 tRNA:Ser-GCT-2-1 transfer RNA:Serine-GCT 2-1 http://flybase.org/reports/FBgn0011970 "FBgn0011968, FBgn0011969, FBgn0051396, FBgn0060054" tRNA_gene AGC codon-amino acid adaptor activity ; GO:0033446 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033446 cytosol ; GO:0005829 | inferred by curator from GO:0033446 "tRNA[Ser][[2b]], AE002708.trna56-SerGCT, tRNA:S:GCT:AE002708-f, CR31396, tRNA:ser, tRNA:S, tRNA:ser2b, tRNA:S2b, tRNA:ser2b:86A, tRNA[[Ser]], chr3R.trna62-SerGCT, tRNA-Ser-GCT-2-1, tRNA:Ser-GCT-2-1, tRNA:S2b:86A, AGC" - CR31396 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083968 CG34132 - http://flybase.org/reports/FBgn0083968 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with SGD:S000003413 protein import into mitochondrial inner membrane ; GO:0045039 | inferred from sequence or structural similarity with SGD:S000003413 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000003413 CG34132 IPR004217:Tim10/DDP family zinc finger CG34132 11-Aug-17 DroID_v2017_08 Drer\timm13 Scer\TIM13 Cele\tin-13 Xtro\timm13 Mmus\Timm13 Hsap\TIMM13 FBgn0032314 CG7309 - http://flybase.org/reports/FBgn0032314 protein_coding_gene citrate transmembrane transporter activity ; GO:0015137 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 succinate transmembrane transporter activity ; GO:0015141 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR001898 succinate transmembrane transport ; GO:0071422 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000815082 CG7309 IPR001898:Solute carrier family 13 CG7309 11-Aug-17 DroID_v2017_08 "Drer\slc13a5b, Drer\slc13a1, Drer\slc13a4, Drer\slc13a2, Drer\slc13a5a, Drer\slc13a3" "Scer\PHO87, Scer\PHO91, Scer\PHO90" "Cele\nac-1, Cele\nac-2, Cele\B0285.6, Cele\nac-3" "Xtro\slc13a2, Xtro\slc13a3, Xtro\slc13a5, Xtro\slc13a4, Xtro\slc13a1" "Mmus\Slc13a5, Mmus\Slc13a4, Mmus\Slc13a3, Mmus\Slc13a1, Mmus\Slc13a2" "Hsap\SLC13A2, Hsap\SLC13A4, Hsap\SLC13A1, Hsap\SLC13A3, Hsap\SLC13A5" viable FBgn0262357 CG43055 - http://flybase.org/reports/FBgn0262357 protein_coding_gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity with Lectin-galC1 induction of bacterial agglutination ; GO:0043152 | inferred from sequence or structural similarity with Lectin-galC1 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Lectin-galC1 "CG43055, MB8.chr2L.pasa.5" "IPR016187:C-type lectin fold, IPR018378:C-type lectin, conserved site, IPR016186:C-type lectin-like/link domain, IPR001304:C-type lectin-like" CG43055 11-Aug-17 DroID_v2017_08 - - - - Mmus\Cd209c - FBgn0031904 CG5149 - http://flybase.org/reports/FBgn0031904 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR017974 - bicellular tight junction ; GO:0005923 | inferred from electronic annotation with InterPro:IPR017974 CG5149 "IPR017974:Claudin, conserved site, IPR006571:TLDc domain" CG5149 11-Aug-17 DroID_v2017_08 "Drer\tldc1, Drer\oxr1b, Drer\LOC792958" Scer\OXR1 Cele\eak-7 Xtro\tldc1 "Mmus\Tldc2, Mmus\Tldc1" "Hsap\TLDC2, Hsap\TLDC1" "viable,fertile" FBgn0000822 fs(1)K1221 female sterile (1) K1221 http://flybase.org/reports/FBgn0000822 - gene - - - fs(1)K1221 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0016998 len leopard http://flybase.org/reports/FBgn0016998 - gene - - - len - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,mitotic cell cycle defective" FBgn0003006 Opt Ophthalmoptera http://flybase.org/reports/FBgn0003006 - gene - - - "ey[Opt], Opt" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029770 CG4151 - http://flybase.org/reports/FBgn0029770 protein_coding_gene - - - CG4151 - CG4151 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0262182 mir-957 mir-957 stem loop http://flybase.org/reports/FBgn0262182 miRNA_gene - muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-957, miR-957, mir-957, CR42889" - CR42889 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,visible" "wing,wing vein,crossvein" FBgn0001124 Got1 Glutamate oxaloacetate transaminase 1 http://flybase.org/reports/FBgn0001124 "FBgn0034079, FBgn0046303" protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839 L-aspartate:2-oxoglutarate aminotransferase activity ; GO:0004069 | inferred from direct assay L-aspartate:2-oxoglutarate aminotransferase activity ; GO:0004069 | inferred from sequence or structural similarity with UniProtKB:P00505 aspartate biosynthetic process ; GO:0006532 | inferred from biological aspect of ancestor with PANTHER:PTN000222846 glutamate biosynthetic process ; GO:0006537 | inferred from direct assay aspartate metabolic process ; GO:0006531 | inferred from sequence or structural similarity with UniProtKB:P00505 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P00505 peroxisome ; GO:0005777 | inferred from sequence model "CG8430, GOT-1, Got-1, Got2, BEST:GH07823, Got1, FBgn 1124, got1" "IPR000796:Aspartate/other aminotransferase, IPR004839:Aminotransferase, class I/classII, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG8430 11-Aug-17 DroID_v2017_08 "Drer\got1, Drer\got2b, Drer\got2a, Drer\got1l1" "Scer\AAT1, Scer\AAT2" "Cele\got-2.2, Cele\got-2.1, Cele\got-1.2" "Xtro\got1, Xtro\got2" "Mmus\Got2, Mmus\Got1l1, Mmus\Got1" "Hsap\GOT1L1, Hsap\GOT1, Hsap\GOT2" "viable,fertile" FBgn0003952 ung uniungula http://flybase.org/reports/FBgn0003952 - gene - - - ung - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "ommatidium,leg" FBgn0033866 CG6280 - http://flybase.org/reports/FBgn0033866 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6280 - CG6280 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065237 l(2)SH2164 lethal (2) SH2164 http://flybase.org/reports/FBgn0065237 gene - - - "l(2)SH2164, l(2)SH2 2164" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035390 scramb2 scramblase 2 http://flybase.org/reports/FBgn0035390 protein_coding_gene phospholipid scramblase activity ; GO:0017128 | inferred from biological aspect of ancestor with PANTHER:PTN000582979 phospholipid scramblase activity ; GO:0017128 | inferred from sequence or structural similarity chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000582979 "scramb2, CG1893, Scramb2" "IPR025659:Tubby C-terminal-like domain, IPR005552:Scramblase" CG1893 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-206p6.1, Drer\LOC100537119, Drer\plscr3a, Drer\si:ch211-71m22.5, Drer\si:dkey-62k3.6, Drer\si:ch211-71m22.3, Drer\si:ch211-71m22.1, Drer\LOC100536708, Drer\plscr3b" Scer\AIM25 "Cele\scrm-8, Cele\scrm-5, Cele\scrm-4, Cele\scrm-3, Cele\scrm-1, Cele\K08D10.18, Cele\scrm-7, Cele\scrm-6, Cele\scrm-2" "Xtro\plscr1, Xtro\plscr3, Xtro\plscr2" "Mmus\1700057G04Rik, Mmus\Plscr4, Mmus\Plscr1, Mmus\Plscr2, Mmus\Plscr5, Mmus\Plscr3" "Hsap\PLSCR4, Hsap\PLSCR3, Hsap\PLSCR2, Hsap\PLSCR1, Hsap\PLSCR5" "viable,visible" trichogen cell FBgn0266234 CR44929 - http://flybase.org/reports/FBgn0266234 non_protein_coding_gene - - - "CR44929, lincRNA.691" - CR44929 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036396 CG17359 - http://flybase.org/reports/FBgn0036396 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG17359 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17359 11-Aug-17 DroID_v2017_08 "Drer\znf281b, Drer\zgc:113265, Drer\vezf1a, Drer\vezf1b, Drer\zgc:174315, Drer\znf1051, Drer\zgc:174650, Drer\klf12b, Drer\si:ch73-266f23.3, Drer\LOC100535691, Drer\znf1137, Drer\znf740a, Drer\zgc:113295, Drer\klf12a, Drer\si:ch73-367f21.6, Drer\zgc:173575, Drer\si:ch211-89o9.6, Drer\zgc:174268, Drer\znf973, Drer\si:ch211-166g5.4, Drer\znf740b, Drer\zgc:113343, Drer\znf281a, Drer\zgc:113030, Drer\zgc:162971, Drer\zgc:113096, Drer\klf3, Drer\si:dkeyp-53d3.6, Drer\znf971, Drer\znf576.2, Drer\zgc:174646, Drer\zgc:173705, Drer\LOC108183284, Drer\zgc:173720, Drer\zgc:194336" Scer\AZF1 "Cele\klf-3, Cele\let-391, Cele\Y55F3AM.14, Cele\eor-1, Cele\M03D4.4, Cele\F58G1.2, Cele\blmp-1" "Xtro\znf668, Xtro\LOC100488817, Xtro\znf180, Xtro\znf568, Xtro\znf184, Xtro\znf33a, Xtro\znf333, Xtro\znf484, Xtro\znf850, Xtro\znf33b, Xtro\znf300" "Mmus\Zbtb45, Mmus\Zfp281, Mmus\Zfp771, Mmus\Zfp46, Mmus\Zfp787, Mmus\Zfp689, Mmus\Maz, Mmus\Zik1, Mmus\Klf12, Mmus\Zfp930, Mmus\Zfp954, Mmus\Gm10778, Mmus\Zkscan4, Mmus\Vezf1, Mmus\Zfp672, Mmus\Zfp772, Mmus\Klf8, Mmus\Klf3, Mmus\Zfp3, Mmus\Zkscan2" "Hsap\ZNF157, Hsap\ZSCAN31, Hsap\ZSCAN30, Hsap\KLF8, Hsap\MAZ, Hsap\ZNF672, Hsap\ZNF154, Hsap\ZNF576, Hsap\ZIK1, Hsap\VEZF1, Hsap\ZNF146, Hsap\ZNF787, Hsap\ZNF740, Hsap\ZNF25, Hsap\ZSCAN9, Hsap\ZNF391, Hsap\ZNF281, Hsap\ZNF774, Hsap\ZNF514, Hsap\ZNF70, Hsap\ZFP3, Hsap\KLF12, Hsap\ZNF793, Hsap\ZNF764, Hsap\ZNF383, Hsap\ZNF165, Hsap\ZNF771, Hsap\ZBTB45, Hsap\ZNF501, Hsap\KLF3" viable FBgn0037758 CG9467 - http://flybase.org/reports/FBgn0037758 protein_coding_gene "oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor ; GO:0016620 | inferred from electronic annotation with InterPro:IPR020830" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR020830 protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 - CG9467 "IPR017986:WD40-repeat-containing domain, IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011333:SKP1/BTB/POZ domain, IPR020830:Glyceraldehyde 3-phosphate dehydrogenase, active site" CG9467 11-Aug-17 DroID_v2017_08 "Drer\shkbp1, Drer\kctd3" - Cele\T23B12.6 "Xtro\kctd3, Xtro\shkbp1" "Mmus\Kctd3, Mmus\Shkbp1" "Hsap\KCTD1, Hsap\SHKBP1, Hsap\KCTD15, Hsap\KCTD3" viable FBgn0265088 CR44199 - http://flybase.org/reports/FBgn0265088 non_protein_coding_gene - - - CR44199 - CR44199 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001517 l(1)10Fk lethal (1) 10Fk http://flybase.org/reports/FBgn0001517 - gene - - - l(1)10Fk - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260031 22M2 - http://flybase.org/reports/FBgn0260031 gene - - - 22M2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0058400 CG40400 - http://flybase.org/reports/FBgn0058400 protein_coding_gene - - - CG40400 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024683 l(1)LefEM1 lethal (1) LefEM1 http://flybase.org/reports/FBgn0024683 - gene - - - "EM1, l(1)LefEM1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015020 Chap31 Chromosome-associated protein 31kD http://flybase.org/reports/FBgn0015020 - gene chromatin binding ; GO:0003682 | inferred from direct assay - - Chap31 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027929 NimB1 Nimrod B1 http://flybase.org/reports/FBgn0027929 FBgn0053119 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with UniProtKB:Q1HAY7 extracellular region ; GO:0005576 | inferred from sequence model "CT25428, DS00180.12, BG:DS00180.12, CG8855, BcDNA:GH07762, CG33119, NimB1, nimB1, nim B1" "IPR009030:Growth factor receptor cysteine-rich domain, IPR000742:EGF-like domain" CG33119 11-Aug-17 DroID_v2017_08 "Drer\pear1, Drer\megf10, Drer\angpt2b, Drer\zgc:194887, Drer\si:ch211-157b11.8, Drer\megf6a, Drer\esm1, Drer\si:ch1073-110a20.3, Drer\tnw, Drer\tnxba, Drer\fga, Drer\angptl3, Drer\fgl2b, Drer\angptl6, Drer\scarf1, Drer\angptl2b, Drer\si:zfos-2330d3.3, Drer\ccbe1, Drer\tnr, Drer\fgg, Drer\fgl2a, Drer\si:ch1073-110a20.1, Drer\megf6b, Drer\LOC100007488, Drer\wu:fj11g02, Drer\zmp:0000000846, Drer\si:ch211-287a12.9, Drer\dkk1a, Drer\tnfaip6, Drer\angptl5, Drer\angptl4, Drer\fgb, Drer\tnc, Drer\fibcd1, Drer\zgc:158328, Drer\si:ch1073-110a20.2, Drer\angptl1a, Drer\angpt4, Drer\zgc:171687, Drer\si:ch211-203k16.3, Drer\si:zfos-2330d3.1, Drer\efemp1, Drer\si:zfos-2330d3.6, Drer\angptl2a, Drer\megf11, Drer\angpt1, Drer\dkk2, Drer\si:zfos-2330d3.8" - "Cele\C08G9.2, Cele\Y43C5A.2, Cele\K10D3.4, Cele\T15B7.1, Cele\Y69H2.10, Cele\B0393.5, Cele\Y69H2.3, Cele\ZK1193.3, Cele\R09H10.5, Cele\ZC504.1, Cele\W05B2.2, Cele\ensh-1, Cele\Y26D4A.12, Cele\Y34B4A.5" "Xtro\mfap4, Xtro\LOC100488177, Xtro\tnn, Xtro\fga, Xtro\tnr, Xtro\angptl2, Xtro\stab2, Xtro\angptl4, Xtro\angptl5, Xtro\tnxb, Xtro\LOC100491105, Xtro\fgg, Xtro\angpt4, Xtro\angpt1, Xtro\fgl2, Xtro\LOC100497330, Xtro\tnc, Xtro\megf11, Xtro\fibcd1, Xtro\fgb, Xtro\fgl1, Xtro\angptl3, Xtro\fcn2, Xtro\fcn1, Xtro\fcn3, Xtro\tnfaip6" "Mmus\Fgb, Mmus\Tnr, Mmus\Angptl4, Mmus\Esm1, Mmus\Angpt2, Mmus\Fga, Mmus\Tnc, Mmus\Scarf1, Mmus\Fgg, Mmus\Fgl1, Mmus\Fgl2, Mmus\Mfap4, Mmus\Angptl2, Mmus\Tnxb, Mmus\Angpt1, Mmus\Fibcd1, Mmus\Tnn, Mmus\Angptl1, Mmus\Megf10, Mmus\Dkk3, Mmus\Pear1, Mmus\Angptl7, Mmus\Dkk2, Mmus\Fcnb, Mmus\Fcna, Mmus\Tnfaip6, Mmus\Angpt4, Mmus\Megf11, Mmus\Angptl3, Mmus\Stab1, Mmus\Angptl6, Mmus\Megf6, Mmus\Egfem1" "Hsap\FGA, Hsap\FCN2, Hsap\ANGPTL4, Hsap\ANGPTL5, Hsap\TNR, Hsap\FGB, Hsap\TNXB, Hsap\FGL2, Hsap\PEAR1, Hsap\MEGF11, Hsap\SCARF1, Hsap\MEGF6, Hsap\FGL1, Hsap\MEGF10, Hsap\FCN3, Hsap\ANGPT1, Hsap\ANGPTL2, Hsap\FGG, Hsap\ANGPT2, Hsap\TNC, Hsap\ANGPTL6, Hsap\ANGPTL1, Hsap\SCARF2, Hsap\TNN, Hsap\FIBCD1, Hsap\ANGPTL3, Hsap\DKK2, Hsap\ANGPTL7, Hsap\ANGPT4, Hsap\TNFAIP6" viable FBgn0025789 anon-17Ad anon-17Ad http://flybase.org/reports/FBgn0025789 - gene - - - anon-17Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067066 Nrt::Wnt4 Nrt::Wnt4 http://flybase.org/reports/FBgn0067066 engineered_fusion_gene - - - Nrt::Wnt4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040058 CG17417 - http://flybase.org/reports/FBgn0040058 protein_coding_gene - - - CG17417 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085362 Vml Vitelline membrane-like http://flybase.org/reports/FBgn0085362 protein_coding_gene structural constituent of vitelline membrane ; GO:0008316 | inferred from sequence model dorsal/ventral axis specification ; GO:0009950 | inferred from genetic interaction with pip vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from sequence model egg coat ; GO:0035805 | inferred from sequence model vitelline envelope ; GO:0060388 | inferred from physical interaction with Vm26Ab vitelline envelope ; GO:0060388 | inferred from direct assay "CG34333, Vml, vml, CRM-80" IPR013135:Vitelline membrane cysteine-rich domain CG34333 11-Aug-17 DroID_v2017_08 Drer\egr1 - Cele\C31G12.4 - - - FBgn0259829 ifm(2)RS13 indirect flight muscle (2) RS13 http://flybase.org/reports/FBgn0259829 gene - adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS13 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable indirect flight muscle FBgn0042206 GstD10 Glutathione S transferase D10 http://flybase.org/reports/FBgn0042206 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTD10, CG17392, CG18548, GstD10, GSTD10, gstd10" "IPR004045:Glutathione S-transferase, N-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold, IPR004046:Glutathione S-transferase, C-terminal" CG18548 11-Aug-17 DroID_v2017_08 "Drer\eef1e1, Drer\gstt1a, Drer\gstr, Drer\vars, Drer\eef1g, Drer\mars, Drer\gstt1b, Drer\gstt2" "Scer\URE2, Scer\YGR201C, Scer\GTT1, Scer\TEF4, Scer\CAM1, Scer\GTT2" "Cele\gst-32, Cele\gst-34" "Xtro\eef1g, Xtro\eef1e1, Xtro\gstt1" "Mmus\Gstt3, Mmus\Gstt1, Mmus\Gstt2, Mmus\Mars, Mmus\Eef1g, Mmus\Eef1e1, Mmus\Vars, Mmus\Gstt4" "Hsap\GSTT2, Hsap\GSTT2B, Hsap\EEF1E1, Hsap\GSTT1, Hsap\MARS, Hsap\EEF1G, Hsap\VARS" viable FBgn0011955 tRNA:Arg-ACG-1-5 transfer RNA:Arginine-ACG 1-5 http://flybase.org/reports/FBgn0011955 "FBgn0003757, FBgn0011947, FBgn0050317, FBgn0050514, FBgn0060092" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "tRNA[arg], DROTG121, tRNA[Arg], tRNA[Arg][[2]], AE002769.trna2-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002769-a, tRNA:arg2:42Aa, CR30317, CR30514, chr2R.trna93-ArgACG, tRNA-Arg-ACG-1-5, tRNA:Arg-ACG-1-5, tRNA:R2:42Aa, CGU" - CR30514 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085794 CR41531 - http://flybase.org/reports/FBgn0085794 non_protein_coding_gene - - - CR41531 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265982 CR44761 - http://flybase.org/reports/FBgn0265982 non_protein_coding_gene - - - CR44761 - CR44761 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069320 X-167-40 X-167-40 http://flybase.org/reports/FBgn0069320 gene - - - X-167-40 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086289 GS3087 - http://flybase.org/reports/FBgn0086289 gene - - - "GS3087, 3087" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026225 l(1)16Fp lethal (1) 16Fp http://flybase.org/reports/FBgn0026225 - gene - - - "ME-VI, l(1)16Fp" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085699 CG41572 - http://flybase.org/reports/FBgn0085699 protein_coding_gene - - - CG41572 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067057 P72 P72 http://flybase.org/reports/FBgn0067057 gene - - - P72 - - 11-Aug-17 DroID_v2017_08 - - - - - - neurophysiology defective FBgn0267097 CR45537 - http://flybase.org/reports/FBgn0267097 non_protein_coding_gene - - - CR45537 - CR45537 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036528 CG7579 - http://flybase.org/reports/FBgn0036528 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 oligosaccharide biosynthetic process ; GO:0009312 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 - "CG7579, dppGalNAcT12" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG7579 11-Aug-17 DroID_v2017_08 "Drer\LOC568645, Drer\galnt11, Drer\LOC103910015, Drer\galnt6, Drer\poc1bl, Drer\galnt7, Drer\LOC100535692, Drer\galnt8a.1, Drer\galnt13, Drer\galnt1, Drer\LOC100334784, Drer\galnt3, Drer\galnt10, Drer\LOC101886587, Drer\galnt18a, Drer\galnt18b, Drer\galnt9, Drer\galnt8b, Drer\wbscr17, Drer\galnt12, Drer\si:ch211-15e22.3, Drer\LOC101882942" - "Cele\gly-11, Cele\gly-8, Cele\gly-10" "Xtro\wbscr17, Xtro\galnt4, Xtro\galnt1, Xtro\galnt15, Xtro\galnt10, Xtro\galnt13, Xtro\galnt7, Xtro\galnt9, Xtro\galnt6.1, Xtro\galnt12" "Mmus\Galnt13, Mmus\Galnt12, Mmus\Galnt1, Mmus\Galnt5, Mmus\Galntl5, Mmus\Galnt4, Mmus\Wbscr17, Mmus\Galnt6, Mmus\Galnt3, Mmus\Galnt15, Mmus\Galnt18, Mmus\Galntl6, Mmus\Galnt7, Mmus\Galnt9, Mmus\Galnt10, Mmus\Galnt11" "Hsap\GALNTL6, Hsap\GALNT1, Hsap\GALNT11, Hsap\GALNT13, Hsap\GALNTL5, Hsap\GALNT8, Hsap\WBSCR17, Hsap\GALNT15, Hsap\POC1B-GALNT4, Hsap\GALNT5, Hsap\GALNT7, Hsap\GALNT9, Hsap\GALNT12, Hsap\GALNT6, Hsap\GALNT10, Hsap\GALNT3, Hsap\GALNT18, Hsap\GALNT4" viable FBgn0082821 Dar Defender against reaper http://flybase.org/reports/FBgn0082821 gene - - - Dar - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266805 CR45267 - http://flybase.org/reports/FBgn0266805 non_protein_coding_gene - - - CR45267 - CR45267 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040265 Transpac\pol Transpac element pol http://flybase.org/reports/FBgn0040265 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - Transpac\pol "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069123 ms(2)Z0738 ms(2)Z0738 http://flybase.org/reports/FBgn0069123 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(2)Z0738 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile primary spermatocyte cyst FBgn0040220 fs(2)BA37 fs(2)BA37 http://flybase.org/reports/FBgn0040220 gene - - - fs(2)BA37 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0045976 PdL3A PdL3A http://flybase.org/reports/FBgn0045976 gene - - - PdL3A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265999 CR44773 - http://flybase.org/reports/FBgn0265999 non_protein_coding_gene - - - CR44773 - CR44773 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266790 CR45255 - http://flybase.org/reports/FBgn0266790 non_protein_coding_gene - - - "CR45255, lincRNA.540" - CR45255 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017621 Eig87F Eig87F http://flybase.org/reports/FBgn0017621 - gene - - - "Eig87, Eig87F" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001351 l(1)1Ef lethal (1) 1Ef http://flybase.org/reports/FBgn0001351 - gene - - - "C24, l(1)1Ef" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,maternal effect" "prothoracic segment,maternal effect,anal pad" FBgn0021905 l(2)k12004 lethal (2) k12004 http://flybase.org/reports/FBgn0021905 - gene - - - l(2)k12004 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034723 CG13506 - http://flybase.org/reports/FBgn0034723 protein_coding_gene - - - "CT32874, CG13506, 13506" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003598:Immunoglobulin subtype 2" CG13506 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-165n16.1, Drer\LOC799279, Drer\dscama, Drer\ncam1b, Drer\lrit3b, Drer\kirrela, Drer\il1rapl1b, Drer\si:ch1073-459j12.1, Drer\sdk1a, Drer\lrit3a, Drer\itgb4, Drer\kirrel3a, Drer\il1rapl2, Drer\igsf9a, Drer\paplna, Drer\kirrelb, Drer\kirrel3l, Drer\sdk1b, Drer\igsf9bb, Drer\kirrel3b, Drer\ush2a, Drer\lrit1b, Drer\lrit1a, Drer\si:dkey-22i16.9, Drer\il1rapl1a" Scer\RDL2 "Cele\wrk-1, Cele\zig-1" "Xtro\papln, Xtro\lrit3, Xtro\kirrel2, Xtro\igsf9b" "Mmus\Tstd3, Mmus\Lrit3, Mmus\Kirrel3, Mmus\Sdk1, Mmus\Papln, Mmus\Il18rap, Mmus\Il1r1, Mmus\Il1rl2, Mmus\Lrit1, Mmus\Igsf9b, Mmus\Il1rap, Mmus\Ptprq, Mmus\Kirrel, Mmus\Kirrel2, Mmus\Il18r1, Mmus\Il1rapl2, Mmus\Il1rapl1, Mmus\Il1rl1" "Hsap\IGSF9B, Hsap\IL1RL2, Hsap\USH2A, Hsap\KIRREL2, Hsap\IL1RAPL1, Hsap\SDK1, Hsap\SIGIRR, Hsap\IL1RAP, Hsap\PAPLN, Hsap\KIRREL, Hsap\IL1RAPL2, Hsap\IL18R1, Hsap\IL1RL1, Hsap\LRIT3, Hsap\IL18RAP, Hsap\IL1R1, Hsap\KIRREL3, Hsap\LRIT1" viable FBgn0065098 RNaseMRP:RNA Ribonuclease MRP RNA http://flybase.org/reports/FBgn0065098 non_protein_coding_gene - rRNA processing ; GO:0006364 | inferred from direct assay - "Dm-342, CR33682, RNaseMRP:RNA, snmRNA:342, RNase MRP RNA, MRP RNA, MRP, RNAseMRP, snmRNA:342 RNAse MRP, chr3R:19555820..19556089, RNase MRP" - CR33682 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage" FBgn0033663 ERp60 ERp60 http://flybase.org/reports/FBgn0033663 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017937 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607" microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 endomembrane system ; GO:0012505 | inferred from direct assay "ERp60, CG8983, D-ERp60, anon-EST:fe3D9, Erp60, Ov6" "IPR005788:Disulphide isomerase, IPR005792:Protein disulphide isomerase, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site" CG8983 11-Aug-17 DroID_v2017_08 "Drer\pdia3, Drer\zgc:77086, Drer\pdia4, Drer\zgc:100906, Drer\zgc:136472, Drer\p4hb, Drer\pdia2, Drer\txndc11" "Scer\MPD2, Scer\PDI1, Scer\EUG1" "Cele\C14B9.2, Cele\pdi-2, Cele\R05D3.9, Cele\pdi-3" "Xtro\txndc11, Xtro\pdia4, Xtro\pdia3, Xtro\pdilt, Xtro\pdia2, Xtro\p4hb" "Mmus\Pdia3, Mmus\Txndc11, Mmus\Pdia4, Mmus\P4hb, Mmus\Pdia2, Mmus\Pdilt" "Hsap\P4HB, Hsap\PDIA3, Hsap\PDIA2, Hsap\PDIA4, Hsap\TXNDC11" "viable,fertile" FBgn0039161 CG13606 - http://flybase.org/reports/FBgn0039161 protein_coding_gene - - - CG13606 - CG13606 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0262605 CG43131 - http://flybase.org/reports/FBgn0262605 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43131 - CG43131 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083086 jaft jaft http://flybase.org/reports/FBgn0083086 gene - Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype decapentaplegic signaling pathway ; GO:0008101 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "group C, Group C, jaft" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032049 Bace beta-site APP-cleaving enzyme http://flybase.org/reports/FBgn0032049 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein autoprocessing ; GO:0016540 | inferred from electronic annotation with InterPro:IPR033145 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 - "anon-WO0140519.142, CG13095, dBace, Bace, dBACE" "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR033145:Cathepsin E, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG13095 11-Aug-17 DroID_v2017_08 "Drer\zgc:63831, Drer\nots, Drer\ren, Drer\zgc:103530, Drer\ctsd" "Scer\YGL258W-A, Scer\PEP4, Scer\YPS1, Scer\BAR1, Scer\YPS7, Scer\YPS3, Scer\MKC7, Scer\YPS6, Scer\YPS5" "Cele\asp-19, Cele\asp-14, Cele\asp-5, Cele\asp-3, Cele\asp-15, Cele\asp-18, Cele\asp-8, Cele\asp-16, Cele\asp-1, Cele\asp-10, Cele\asp-12, Cele\asp-9, Cele\asp-7, Cele\asp-4, Cele\asp-6, Cele\asp-17, Cele\asp-2, Cele\asp-13" "Xtro\pga4, Xtro\mgc108380, Xtro\ctsd, Xtro\napsa, Xtro\LOC496913, Xtro\bace1, Xtro\ren, Xtro\bace2, Xtro\ctse, Xtro\pgc" "Mmus\Cym, Mmus\Bace1, Mmus\Ren1, Mmus\Bace2, Mmus\Pgc, Mmus\Ren2, Mmus\Pga5, Mmus\Ctsd, Mmus\Ctse, Mmus\Napsa" "Hsap\NAPSA, Hsap\PGA4, Hsap\PGA5, Hsap\PGA3, Hsap\PGC, Hsap\CTSD, Hsap\REN, Hsap\BACE1, Hsap\CTSE, Hsap\BACE2" "lethal,neuroanatomy defective,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage,progressive,partially lethal - majority die" "cell body rind of lamina,lamina neuropil,adult brain,subretinal glial cell,adult epithelial glial cell,progressive,lamina" DRSC02197 K 0.878387914 -1.381548336 0.121947144 0.695867782 0.701494532 2.493276147 FBgn0052547 CG32547 - http://flybase.org/reports/FBgn0052547 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model" "CG12610, CG15050, CG15049, CG32547" "IPR017452:GPCR, rhodopsin-like, 7TM, IPR000276:G protein-coupled receptor, rhodopsin-like" CG32547 11-Aug-17 DroID_v2017_08 - - "Cele\ckr-1, Cele\ckr-2, Cele\R13H4.7, Cele\C34B4.3" - - - "viable,fertile" FBgn0003960 urd urdur http://flybase.org/reports/FBgn0003960 - gene - - - urd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0040773 COX7C Cytochrome c oxidase subunit 7C http://flybase.org/reports/FBgn0040773 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P15954 cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with SGD:S000004387 cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000329966 "negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with SGD:S000004387 mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000329966" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with SGD:S000004387 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000329966 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P15954 "VIIc, anon-EST:fe3A1, BcDNA:LD14731, CG2249, CoAVIIc, COXO, COX7C, CoVIIc" IPR004202:Cytochrome c oxidase subunit VIIc CG2249 11-Aug-17 DroID_v2017_08 Drer\cox7c Scer\COX8 Cele\F26E4.6 Xtro\cox7c Mmus\Cox7c Hsap\COX7C "viable,visible,fertile" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" DRSC06831 E -1.341455284 -0.262917884 -2.180745296 0.121057594 0.451655428 0.893069883 FBgn0028581 mei-217 mei-217 http://flybase.org/reports/FBgn0028581 protein_coding_gene - female meiotic division ; GO:0007143 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype - "CG33067, CG33935, mei-217" - CG33935 11-Aug-17 DroID_v2017_08 - - - - - - "viable,meiotic cell cycle defective,female,fertile,recessive,wild-type" meiosis I | female DRSC20349 K 0.865623525 0.665245472 0.623441472 0.246631422 -1.52710277 -0.215843461 FBgn0264357 SNF4Agamma SNF4/AMP-activated protein kinase gamma subunit http://flybase.org/reports/FBgn0264357 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 protein kinase binding ; GO:0019901 | inferred from sequence or structural similarity with HGNC:9386 autophagy ; GO:0006914 | inferred from mutant phenotype lipid metabolic process ; GO:0006629 | inferred from mutant phenotype behavioral response to starvation ; GO:0042595 | inferred from mutant phenotype sequestering of triglyceride ; GO:0030730 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok cellular response to starvation ; GO:0009267 | inferred from mutant phenotype cholesterol homeostasis ; GO:0042632 | inferred from mutant phenotype positive regulation of cell cycle ; GO:0045787 | inferred from genetic interaction with COX5A nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "SNF4Agamma, SNF4, AMPKgamma, CG17299, Snfgamma, loe, Snfg, SNF4Ag, SNF4A, FBgn0025803, SNF4a, EP3015b, CG5806, anon-WO0257455.21, anon-WO0118547.575, anon-WO0118547.338, AMPgamma, l(3)S005042, 0050/42, 0127/19, l(3)S012719, loeI, AMPK&ggr, snf4, SNF4gamma, SNF4A-gamma, AMPK-&ggr" "IPR000644:CBS domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG17299 11-Aug-17 DroID_v2017_08 "Drer\prkag3b, Drer\prkag2a, Drer\prkag2b, Drer\prkag3a, Drer\prkag1" "Scer\SDS23, Scer\SNF4, Scer\SDS24" "Cele\aakg-1, Cele\aakg-4, Cele\aakg-3, Cele\aakg-5, Cele\aakg-2" "Xtro\prkag3, Xtro\prkag1, Xtro\prkag2" "Mmus\Prkag1, Mmus\Prkag2, Mmus\Prkag3" "Hsap\PRKAG3, Hsap\PRKAG1, Hsap\PRKAG2" DRSC13461 EK -0.231549158 0.16235906 -0.657540346 -1.615298176 0.863096522 1.709123044 FBgn0267118 CR45558 - http://flybase.org/reports/FBgn0267118 non_protein_coding_gene - - - CR45558 - CR45558 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004389 bnk bottleneck http://flybase.org/reports/FBgn0004389 - protein_coding_gene "phosphatidylinositol-3,4,5-trisphosphate binding ; GO:0005547 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from direct assay" membrane organization ; GO:0061024 | non-traceable author statement actomyosin contractile ring assembly ; GO:0000915 | non-traceable author statement actin filament organization ; GO:0007015 | traceable author statement actin filament bundle organization ; GO:0061572 | inferred from direct assay regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype cellularization ; GO:0007349 | traceable author statement stress fiber ; GO:0001725 | colocalizes_with inferred from direct assay actin filament ; GO:0005884 | non-traceable author statement actin filament ; GO:0005884 | inferred from direct assay "bnk, CG1480, Bnk" - CG1480 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | cycle 14 , embryonic stage | 2-4 hr " organism

wild-type FBgn0086244 grk::cni - http://flybase.org/reports/FBgn0086244 engineered_fusion_gene - - - "grk::cni, Grk-Cni" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002978 obt obtuse http://flybase.org/reports/FBgn0002978 - gene - - - obt - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,thorax,eye" FBgn0262121 Lp5 - http://flybase.org/reports/FBgn0262121 gene - - - Lp5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037372 CG2091 - http://flybase.org/reports/FBgn0037372 protein_coding_gene m7G(5')pppN diphosphatase activity ; GO:0050072 | inferred from biological aspect of ancestor with PANTHER:PTN000312213 RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from biological aspect of ancestor with PANTHER:PTN000312213 lateral inhibition ; GO:0046331 | inferred from mutant phenotype deadenylation-dependent decapping of nuclear-transcribed mRNA ; GO:0000290 | inferred from biological aspect of ancestor with PANTHER:PTN000312213 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000312213 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000312213 CG2091 "IPR011145:Scavenger mRNA decapping enzyme, N-terminal, IPR011146:HIT-like domain, IPR008594:Scavenger mRNA decapping enzyme DcpS/DCS2" CG2091 11-Aug-17 DroID_v2017_08 Drer\dcps "Scer\DCS2, Scer\DCS1" Cele\dcs-1 Xtro\dcps Mmus\Dcps Hsap\DCPS "viable,visible" "chaeta,supernumerary" FBgn0030890 CG7536 - http://flybase.org/reports/FBgn0030890 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004342 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000081883 CG7536 "IPR004331:SPX domain, IPR004342:EXS, C-terminal" CG7536 11-Aug-17 DroID_v2017_08 "Drer\xpr1b, Drer\xpr1a" "Scer\ERD1, Scer\SYG1, Scer\VTC3, Scer\VTC4, Scer\VTC2" Cele\Y39A1A.22 Xtro\xpr1 Mmus\Xpr1 Hsap\XPR1 "viable,fertile" FBgn0040721 CG14350 - http://flybase.org/reports/FBgn0040721 protein_coding_gene - - - CG14350 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033597 Cpr47Ea Cuticular protein 47Ea http://flybase.org/reports/FBgn0033597 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr47Ea, CG9079, DmelCpr47Ea" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG9079 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\math-34, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0262829 LA2.1 - http://flybase.org/reports/FBgn0262829 nuclear_gene - regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype - "LA2.1, Doc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039033 Or94a Odorant receptor 94a http://flybase.org/reports/FBgn0039033 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "94a, DOR108, 94D.1, CG17241, Or94a" "IPR004117:Olfactory receptor, insect" CG17241 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,viable" FBgn0035544 CG15021 - http://flybase.org/reports/FBgn0035544 protein_coding_gene - - - "CT34875, CG15021" - CG15021 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0032689 CG10413 - http://flybase.org/reports/FBgn0032689 protein_coding_gene potassium:chloride symporter activity ; GO:0015379 | inferred from biological aspect of ancestor with PANTHER:PTN000930406 potassium ion symporter activity ; GO:0022820 | inferred from biological aspect of ancestor with PANTHER:PTN000930406 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004841 ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR018491 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR004841, InterPro:IPR018491" CG10413 "IPR004841:Amino acid permease/ SLC12A domain, IPR018491:SLC12A transporter, C-terminal" CG10413 11-Aug-17 DroID_v2017_08 "Drer\zgc:153039, Drer\slc12a9" Scer\VHC1 Cele\T04B8.5 "Xtro\slc12a9, Xtro\LOC100498108" Mmus\Slc12a9 Hsap\SLC12A9 "viable,partially lethal - majority die,some die during pupal stage" FBgn0267540 CR45880 - http://flybase.org/reports/FBgn0267540 non_protein_coding_gene - - - CR45880 - CR45880 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266819 CR45281 - http://flybase.org/reports/FBgn0266819 non_protein_coding_gene - - - "lincRNA.S2433, CR45281" - CR45281 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038941 CG7080 - http://flybase.org/reports/FBgn0038941 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7080 - CG7080 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000663 fla flat eye http://flybase.org/reports/FBgn0000663 - gene - - - fla - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,good,male,male fertile,female fertile,reduced,female" "wing,eye" FBgn0011087 l(1)Q45 lethal (1) Q45 http://flybase.org/reports/FBgn0011087 FBgn0010210 gene - - - l(1)Q45 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052329 tRNA:Glu-CTC-3-3 transfer RNA:Glutamic acid-CTC 3-3 http://flybase.org/reports/FBgn0052329 tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "CR32329, AE002584.trna5-GluCTC, tRNA:E:CTC:AE002584-c, chr3L.trna5-GluCTC, tRNA:Glu-CTC-3-3, tRNA:CR32329, tRNA-Glu-CTC-3-3, GAG" - CR32329 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032979 Clamp Chromatin-linked adaptor for MSL proteins http://flybase.org/reports/FBgn0032979 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG1832, Clamp, CLAMP" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1832 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-367f21.6, Drer\si:zfos-1425h8.1, Drer\si:dkey-166n8.9, Drer\znf362a, Drer\zgc:113886, Drer\ikzf1, Drer\si:ch211-154o6.2, Drer\znf362b, Drer\znf384l, Drer\zgc:175107" "Scer\CMR3, Scer\YPR015C" "Cele\pat-9, Cele\M03D4.4, Cele\fezf-1, Cele\lin-29, Cele\Y55F3AM.14" "Xtro\ikzf3, Xtro\zbtb49, Xtro\znf574, Xtro\ikzf2, Xtro\ikzf4, Xtro\znf362, Xtro\znf384, Xtro\znf420" "Mmus\Zbtb49, Mmus\Ikzf1, Mmus\Zfp935, Mmus\AU041133, Mmus\Zfp90, Mmus\Zfp37, Mmus\Ikzf2, Mmus\Zfp13, Mmus\Zfp808, Mmus\Zfp934, Mmus\Zfp362, Mmus\Gm3604, Mmus\Ikzf4, Mmus\Ikzf3, Mmus\Zfp46, Mmus\Zkscan2, Mmus\Zfp112, Mmus\Zscan2, Mmus\Zfp260" "Hsap\ZNF418, Hsap\IKZF1, Hsap\IKZF3, Hsap\ZKSCAN7, Hsap\ZNF264, Hsap\ZNF70, Hsap\ZNF391, Hsap\ZNF662, Hsap\ZKSCAN8, Hsap\ZKSCAN2, Hsap\ZNF398, Hsap\ZNF32, Hsap\ZNF436, Hsap\ZNF362, Hsap\ZNF28, Hsap\BCL6, Hsap\ZNF852, Hsap\ZSCAN2, Hsap\ZNF675, Hsap\ZNF112, Hsap\ZNF225, Hsap\ZNF146, Hsap\ZNF286B, Hsap\ZNF320, Hsap\ZNF761, Hsap\ZNF286A, Hsap\ZBTB24, Hsap\IKZF4, Hsap\ZNF3, Hsap\ZNF384, Hsap\IKZF2, Hsap\ZNF229, Hsap\ZNF808, Hsap\ZFP37, Hsap\ZNF501, Hsap\ZNF610, Hsap\ZNF883, Hsap\ZNF79, Hsap\ZNF266" viable DRSC21682 EK -0.951239662 1.467172101 -0.86171823 -1.864013893 -1.115280655 1.552271836 FBgn0263489 CR43604 - http://flybase.org/reports/FBgn0263489 non_protein_coding_gene - - - "ncRNA_39, chr2L:8485781..8485873, CR43604, unsRNA:d-a" - CR43604 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005490 l(1)ts2320 lethal (1) ts2320 http://flybase.org/reports/FBgn0005490 - gene - - - l(1)ts2320 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0030510 CG12177 - http://flybase.org/reports/FBgn0030510 protein_coding_gene purine nucleosidase activity ; GO:0008477 | inferred from biological aspect of ancestor with PANTHER:PTN000266727 purine nucleoside catabolic process ; GO:0006152 | inferred from biological aspect of ancestor with PANTHER:PTN000266727 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000266727 CG12177 "IPR001910:Inosine/uridine-preferring nucleoside hydrolase domain, IPR023186:Inosine/uridine-preferring nucleoside hydrolase" CG12177 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-4e7.3, Drer\si:ch211-201h21.5" Scer\URH1 "Cele\Y43F8C.13, Cele\F13H8.3" "Xtro\LOC548390, Xtro\LOC100145000, Xtro\LOC734042" - - viable DRSC19437 I -1.565409413 1.145464011 -0.051409249 0.2078667 0.921473722 -0.597064186 FBgn0034718 wdp windpipe http://flybase.org/reports/FBgn0034718 protein_coding_gene protein kinase inhibitor activity ; GO:0004860 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VWE0 cytokine-mediated signaling pathway ; GO:0019221 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype tissue homeostasis ; GO:0001894 | inferred from mutant phenotype negative regulation of protein kinase activity ; GO:0006469 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 negative regulation of stem cell proliferation ; GO:2000647 | inferred from mutant phenotype trachea development ; GO:0060438 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CT39092, CT11415, CG30504, CG3413, wdp" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG3413 11-Aug-17 DroID_v2017_08 "Drer\rtn4rl2a, Drer\rtn4rl1b, Drer\rtn4rl2b, Drer\si:ch211-237i5.4, Drer\rtn4r, Drer\nyx" - - - "Mmus\Rtn4rl1, Mmus\Nyx, Mmus\Rtn4rl2, Mmus\Rtn4r, Mmus\Slitrk5" "Hsap\RTN4R, Hsap\NYX, Hsap\RTN4RL2, Hsap\SLITRK4, Hsap\RTN4RL1" viable FBgn0023535 arg arginase http://flybase.org/reports/FBgn0023535 "FBgn0024982, FBgn0029528" protein_coding_gene "metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR006035, InterPro:IPR014033 arginase activity ; GO:0004053 | inferred from sequence or structural similarity with UniProtKB:P78540" arginine catabolic process to ornithine ; GO:0019547 | inferred from sequence or structural similarity with UniProtKB:P78540 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P78540 "arg, EG:65F1.3, EG:171D11.4, CG18104, Arg" "IPR006035:Ureohydrolase, IPR014033:Arginase" CG18104 11-Aug-17 DroID_v2017_08 "Drer\arg2, Drer\arg1" Scer\CAR1 Cele\T21F4.1 "Xtro\arg1, Xtro\arg2" "Mmus\Arg1, Mmus\Arg2" "Hsap\ARG1, Hsap\ARG2" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0262169 magu magu http://flybase.org/reports/FBgn0262169 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR019577 heparan sulfate proteoglycan binding ; GO:0043395 | inferred from direct assay" regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype positive regulation of BMP signaling pathway ; GO:0030513 | inferred from direct assay germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR019577 extracellular region ; GO:0005576 | inferred from direct assay external side of plasma membrane ; GO:0009897 | colocalizes_with inferred from direct assay "PENT, pent, CG2264, CT7504, magu, Pent" "IPR000716:Thyroglobulin type-1, IPR002048:EF-hand domain, IPR002350:Kazal domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR019577:SPARC/Testican, calcium-binding domain" CG2264 11-Aug-17 DroID_v2017_08 "Drer\igfbp3, Drer\igfbp2b, Drer\igfbp6a, Drer\igfbp1a, Drer\igfbp5b, Drer\igfbp2a, Drer\igfbp6b, Drer\smoc2, Drer\igfbp1b, Drer\igfbp5a, Drer\sparc, Drer\smoc1" - "Cele\T04F3.2, Cele\nid-1" "Xtro\igfbp5, Xtro\igfbp1, Xtro\igfbp4, Xtro\igfbp2" "Mmus\Igfbp3, Mmus\Igfbp1, Mmus\Igfbp4, Mmus\Igfbp2, Mmus\Smoc2, Mmus\Smoc1, Mmus\Sparc, Mmus\Igfbp6, Mmus\Igfbp5" "Hsap\SPOCK1, Hsap\SPARC, Hsap\IGFBP4, Hsap\IGFBP5, Hsap\IGFBP3, Hsap\IGFBP6, Hsap\SPARCL1, Hsap\SMOC2, Hsap\IGFBP1, Hsap\IGFBP2, Hsap\SPOCK2, Hsap\SMOC1, Hsap\TG" FBgn0031937 CG13795 - http://flybase.org/reports/FBgn0031937 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 "CT33284, CG13795" IPR000175:Sodium:neurotransmitter symporter CG13795 11-Aug-17 DroID_v2017_08 Drer\zgc:158225 - Cele\snf-6 - Mmus\Slc6a7 Hsap\SLC6A7 viable FBgn0053645 CG33645 - http://flybase.org/reports/FBgn0053645 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33645 IPR010512:Protein of unknown function DUF1091 CG33645 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060893 l(3)S044505 lethal (3) S044505 http://flybase.org/reports/FBgn0060893 gene - - - "0445/05, l(3)S044505" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0004734 l(3)85Da lethal (3) 85Da http://flybase.org/reports/FBgn0004734 - gene - - - "l(3)85Da-1, l(3)85Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267344 l(4)7-M484 lethal (4) 7-M484 http://flybase.org/reports/FBgn0267344 gene - - - l(4)7-M484 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026428 HDAC6 Histone deacetylase 6 http://flybase.org/reports/FBgn0026428 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001607 histone deacetylase activity ; GO:0004407 | inferred from direct assay histone deacetylase activity ; GO:0004407 | inferred from mutant phenotype deacetylase activity ; GO:0019213 | inferred from mutant phenotype "neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay respiratory electron transport chain ; GO:0022904 | inferred from direct assay histone deacetylation ; GO:0016575 | inferred from mutant phenotype histone deacetylation ; GO:0016575 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay "dmHDA404, HDAC, dHDAC6, DmHDAC2, dHDAC2, HDAC2, CG6170, HDAC6, DHDAC2, hdac6" "IPR000286:Histone deacetylase superfamily, IPR001607:Zinc finger, UBP-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR023801:Histone deacetylase domain" CG6170 11-Aug-17 DroID_v2017_08 "Drer\hdac6, Drer\hdac10, Drer\hdac5, Drer\hdac9b, Drer\hdac4, Drer\hdac7b" "Scer\HOS3, Scer\HDA1" "Cele\hda-10, Cele\hda-4, Cele\hda-6, Cele\hda-5" "Xtro\hdac9, Xtro\hdac6, Xtro\hdac7, Xtro\hdac4" "Mmus\Hdac9, Mmus\Hdac5, Mmus\Hdac7, Mmus\Hdac6, Mmus\Hdac10, Mmus\Hdac4" "Hsap\HDAC6, Hsap\HDAC10, Hsap\HDAC7, Hsap\HDAC4, Hsap\LOC285556, Hsap\HDAC9, Hsap\HDAC5" "viable,fertile,lethal" FBgn0260043 33N15 - http://flybase.org/reports/FBgn0260043 gene - - - 33N15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0005640 Eip63E Ecdysone-induced protein 63E http://flybase.org/reports/FBgn0005640 "FBgn0016695, FBgn0024942" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity with SGD:S000000364 inferred from mutant phenotype protein kinase activity ; GO:0004672 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Pif2 inferred from physical interaction with Pif1B protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement cyclin binding ; GO:0030332 | inferred from mutant phenotype" metamorphosis ; GO:0007552 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000000364 embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement developmental growth ; GO:0048589 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 plasma membrane ; GO:0005886 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "PFTAIRE, cdc2-63E, L63, CG10579, Eip63E, EIP63E, Pftaire" "IPR018506:Cytochrome b5, heme-binding site, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG10579 11-Aug-17 DroID_v2017_08 "Drer\LOC100536316, Drer\cdk1, Drer\cdk5, Drer\si:dkey-166c18.1, Drer\cdk15, Drer\cdk16, Drer\cdk14, Drer\cdk17, Drer\cdk21, Drer\cdk2, Drer\cdk4, Drer\cdk6" "Scer\CDC28, Scer\CAK1, Scer\PHO85" "Cele\cdk-5, Cele\ZC123.4, Cele\pct-1" "Xtro\cdk5, Xtro\cdk6, Xtro\cdk17, Xtro\cdk16, Xtro\cdk15, Xtro\cdk14, Xtro\cdk2, Xtro\cdk1, Xtro\cdk4, Xtro\cdk18" "Mmus\E030030I06Rik, Mmus\Cdk6, Mmus\Cdk1, Mmus\Cdk2, Mmus\Cdk16, Mmus\Cdk17, Mmus\Cdk14, Mmus\Cdk15, Mmus\Cdk18, Mmus\Cdk4, Mmus\Cdk5" "Hsap\CDK15, Hsap\CDK4, Hsap\CDK1, Hsap\CDK17, Hsap\CDK6, Hsap\CDK5, Hsap\CDK18, Hsap\CDK2, Hsap\CDK3, Hsap\CDK16, Hsap\CDK14" " embryonic stage , embryonic stage -- adult stage " " myoblast

, anterior midgut proper primordium

, tracheal precursor cell

, posterior midgut proper primordium

, embryonic glial cell

, glial cell

, embryonic central nervous system

" "viable,fertile,wild-type,lethal,polyphasic,maternal effect,small body,developmental rate defective,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of larval stage,recessive,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "polytene chromosome,leg,pupa,head,mesothoracic tergum" FBgn0040359 CG11380 - http://flybase.org/reports/FBgn0040359 protein_coding_gene - - - "EG:BACR42I17.7, CG11380" - CG11380 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051234 CG31234 - http://flybase.org/reports/FBgn0051234 protein_coding_gene - - - CG31234 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003750 tri trident http://flybase.org/reports/FBgn0003750 - gene - - - "b-l, tri" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,partially,body color defective,recessive" "trident,scutellum,adult thorax,thorax & cuticle" FBgn0265349 Sfp33A4 Seminal fluid protein 33A4 http://flybase.org/reports/FBgn0265349 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp33A4, anon-SAGE:Wang-036" - CG42604 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030769 CG13012 - http://flybase.org/reports/FBgn0030769 protein_coding_gene - - - CG13012 - CG13012 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041618 SM3-2 SM3-2 http://flybase.org/reports/FBgn0041618 gene - - - SM3-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000450 dic dicephalic http://flybase.org/reports/FBgn0000450 - gene - determination of left/right symmetry ; GO:0007368 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype - dic - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,semidominant,female sterile" "egg chamber,oocyte,embryonic proventriculus,follicle cell,maternal effect,nurse cell,dorsal appendage,micropyle | maternal effect" FBgn0005099 fs(3)110-8 female sterile (3) 110-8 http://flybase.org/reports/FBgn0005099 - gene - - - fs(3)110-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" endochorion FBgn0010129 l(1)tsG2 lethal (1) tsG2 http://flybase.org/reports/FBgn0010129 - gene - - - l(1)tsG2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cold sensitive" FBgn0003524 stf stormfront http://flybase.org/reports/FBgn0003524 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available stf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "denticle belt,dorsal closure embryo" FBgn0010028 E(Dl)F25 Enhancer of Delta F25 http://flybase.org/reports/FBgn0010028 - gene - - - E(Dl)F25 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034641 mahj mahjong http://flybase.org/reports/FBgn0034641 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein ubiquitination ; GO:0016567 | inferred from electronic annotation with InterPro:IPR033270 cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype - "BcDNA:SD08722, anon-WO0172774.151, mahj, VprBP, CG10080" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR006594:LIS1 homology motif, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR033270:VPRBP/DCAF1 family" CG10080 11-Aug-17 DroID_v2017_08 - - Cele\dcaf-1 Xtro\vprbp Mmus\Vprbp Hsap\DCAF1 "developmental rate defective,increased cell death,cell non-autonomous,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,lethal,viable,visible" "wing disc,cell non-autonomous,somatic clone,trichogen cell,tormogen cell" DRSC04053 IK -3.034989139 -0.758681823 -1.22066499 -0.609229107 1.553559547 0.734936356 FBgn0263076 Klp54D Kinesin-like protein at 54D http://flybase.org/reports/FBgn0263076 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "CG43323, CG15844, KLP1, Klp1, Klp54D, DmKlp54D, KLP54D, KIF 12, KIF12" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR028763:Kinesin-like protein KIF12" CG43323 11-Aug-17 DroID_v2017_08 "Drer\LOC100331925, Drer\kif26bb, Drer\kif17, Drer\kif26aa, Drer\LOC100333558, Drer\kif26ba, Drer\kif15, Drer\si:dkey-86l18.8" Scer\KIP3 - "Xtro\kif15, Xtro\kif3a, Xtro\kif9, Xtro\kif26a" "Mmus\Kif17, Mmus\Kif15, Mmus\Kif6, Mmus\Kif26a, Mmus\Kif9, Mmus\Kif12, Mmus\Kif26b" "Hsap\KIF9, Hsap\KIF17, Hsap\KIF6, Hsap\KIF26B, Hsap\KIF20A, Hsap\KIF26A, Hsap\KIF3A, Hsap\KIF15, Hsap\KIF12" FBgn0084556 aha angsthase http://flybase.org/reports/FBgn0084556 gene - adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype - "G74, aha" - - 11-Aug-17 DroID_v2017_08 - - - - - - "locomotor behavior defective,recessive" FBgn0015423 l(1)18DEd lethal (1) 18DEd http://flybase.org/reports/FBgn0015423 - gene - - - "l(1)18DEa, l(1)18DEd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058221 CG40221 - http://flybase.org/reports/FBgn0058221 protein_coding_gene - - - CG40221 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266957 CR45408 - http://flybase.org/reports/FBgn0266957 non_protein_coding_gene - - - CR45408 - CR45408 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039846 PNPase Polynucleotide phosphorylase http://flybase.org/reports/FBgn0039846 protein_coding_gene "3'-5'-exoribonuclease activity ; GO:0000175 | inferred from electronic annotation with InterPro:IPR015848 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088, InterPro:IPR012162, InterPro:IPR015848 polyribonucleotide nucleotidyltransferase activity ; GO:0004654 | inferred from electronic annotation with InterPro:IPR012162" mRNA catabolic process ; GO:0006402 | inferred from electronic annotation with InterPro:IPR012162 RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR015848 regulation of mitochondrial mRNA stability ; GO:0044528 | inferred from mutant phenotype - "PNPase, dmpnpase, CG11337" "IPR001247:Exoribonuclease, phosphorolytic domain 1, IPR003029:S1 domain, IPR004088:K Homology domain, type 1, IPR012162:Polyribonucleotide nucleotidyltransferase, IPR012340:Nucleic acid-binding, OB-fold, IPR027408:PNPase/RNase PH domain, IPR015847:Exoribonuclease, phosphorolytic domain 2, IPR015848:Polyribonucleotide nucleotidyltransferase, RNA-binding domain, IPR020568:Ribosomal protein S5 domain 2-type fold" CG11337 11-Aug-17 DroID_v2017_08 Drer\pnpt1 - Cele\BE0003N10.1 Xtro\pnpt1 Mmus\Pnpt1 Hsap\PNPT1 "viable,fertile" DRSC14304 K -0.418267901 0.093262813 -0.117566202 0.002624117 -1.750292106 -0.551630815 FBgn0266953 CR45404 - http://flybase.org/reports/FBgn0266953 non_protein_coding_gene - - - CR45404 - CR45404 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005506 l(2)24EFd lethal (2) 24EFd http://flybase.org/reports/FBgn0005506 - gene - - - "l(2)Gr.IV, l(2)24EFd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046327 l(3)S069605b lethal (3) S069605b http://flybase.org/reports/FBgn0046327 gene - - - "0696/05, l(3)S079415b, l(3)S069605b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261831 CG42763 - http://flybase.org/reports/FBgn0261831 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42763 - CG42763 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037279 CG1129 - http://flybase.org/reports/FBgn0037279 protein_coding_gene nucleotidyltransferase activity ; GO:0016779 | inferred from electronic annotation with InterPro:IPR005835 biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR005835 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype - CG1129 "IPR005835:Nucleotidyl transferase domain, IPR018357:Hexapeptide transferase, conserved site, IPR029044:Nucleotide-diphospho-sugar transferases, IPR001451:Hexapeptide repeat" CG1129 11-Aug-17 DroID_v2017_08 Drer\gmppb Scer\PSA1 Cele\tag-335 Xtro\gmppb "Mmus\Gmppb, Mmus\Amigo3" Hsap\GMPPB "neuroanatomy defective,lethal" "mushroom body & axon7B,Kenyon cell,adult mushroom body" FBgn0259140 CG42255 - http://flybase.org/reports/FBgn0259140 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" - cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG42255, CG32092, CT18701, CG5956, CG32094" "IPR000742:EGF-like domain, IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000859:CUB domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site" CG42255 11-Aug-17 DroID_v2017_08 "Drer\cubn, Drer\LOC100003133, Drer\mep1a.2, Drer\mep1b, Drer\bmp1b, Drer\nrp1a, Drer\csmd2, Drer\he2, Drer\c6ast3, Drer\he1b, Drer\bmp1a, Drer\si:cabz01033205.3, Drer\mep1a.1, Drer\tnfaip6, Drer\nrp2b, Drer\tll1, Drer\npsn, Drer\nrp1b, Drer\c6ast4, Drer\he1a, Drer\LOC797085, Drer\c6ast1, Drer\pcolce2b, Drer\pcolce2a, Drer\si:ch73-40a17.3" - "Cele\nas-8, Cele\nas-6, Cele\nas-2, Cele\nas-1, Cele\nas-15, Cele\nas-12, Cele\nas-13, Cele\nas-14, Cele\Y19D10A.6, Cele\nas-39, Cele\nas-4, Cele\ZC116.3, Cele\nas-7" "Xtro\bmp1, Xtro\mep1a, Xtro\LOC100492324, Xtro\cubn, Xtro\mep1b, Xtro\tll1, Xtro\LOC100489456, Xtro\tnfaip6, Xtro\uvs.2, Xtro\tll2, Xtro\mfrp, Xtro\accs" "Mmus\Mep1a, Mmus\Csmd1, Mmus\Mfrp, Mmus\Pcolce, Mmus\Pcolce2, Mmus\Bmp1, Mmus\Cubn, Mmus\Astl, Mmus\Nrp1, Mmus\Tnfaip6, Mmus\Tll1, Mmus\Adgrg6, Mmus\Mep1b, Mmus\Nrp2, Mmus\Tll2" "Hsap\MEP1B, Hsap\MEP1A, Hsap\CSMD2, Hsap\TLL1, Hsap\PCOLCE2, Hsap\NRP2, Hsap\CSMD3, Hsap\CSMD1, Hsap\CUBN, Hsap\PCOLCE, Hsap\NRP1, Hsap\TLL2, Hsap\ADGRG6, Hsap\TNFAIP6, Hsap\BMP1, Hsap\SCUBE2, Hsap\MFRP, Hsap\ASTL" FBgn0000523 dwx dwarfex http://flybase.org/reports/FBgn0000523 - gene - - - dwx - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,adult abdomen,adult thorax" FBgn0267103 CR45543 - http://flybase.org/reports/FBgn0267103 non_protein_coding_gene - - - "lincRNA.973, CR45543" - CR45543 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013713 Abl::Abelson\v-Abl v-Abl http://flybase.org/reports/FBgn0013713 - engineered_fusion_gene - - - Abl::Abelson\v-Abl - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0025875 opus\pol opus element pol http://flybase.org/reports/FBgn0025875 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "ORF2, yoyo\pol, yoyo\Pol, opus\pol, pol" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263507 CR43496 - http://flybase.org/reports/FBgn0263507 non_protein_coding_gene - - - CR43496 - CR43496 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035980 mRRF1 mitochondrial ribosome recycling factor 1 http://flybase.org/reports/FBgn0035980 protein_coding_gene ribosomal large subunit binding ; GO:0043023 | inferred from biological aspect of ancestor with PANTHER:PTN000469808 translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN000469808 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with SGD:S000001080 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000001080 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000469809 "CG4447, mRRF1" "IPR002661:Ribosome recycling factor, IPR023584:Ribosome recycling factor domain" CG4447 11-Aug-17 DroID_v2017_08 Drer\mrrf Scer\RRF1 Cele\mrrf-1 Xtro\mrrf Mmus\Mrrf Hsap\MRRF viable FBgn0027163 l(2)KC-C l(2)Karp and Cherbas C http://flybase.org/reports/FBgn0027163 - gene - - - "C, l(2)KC-C" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014390 su(lz) suppressor of lozenge http://flybase.org/reports/FBgn0014390 - gene - - - su(lz) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030246 CG1582 - http://flybase.org/reports/FBgn0030246 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:15815 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 helicase activity ; GO:0004386 | inferred from sequence or structural similarity RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000433398 "cg1582, CG1582" "IPR000571:Zinc finger, CCCH-type, IPR001650:Helicase, C-terminal, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR006575:RWD domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR011545:DEAD/DEAH box helicase domain" CG1582 11-Aug-17 DroID_v2017_08 "Drer\tdrd9, Drer\dhx9, Drer\dhx36, Drer\dhx29, Drer\dhx30, Drer\dhx57" Scer\YLR419W "Cele\F52B5.3, Cele\rha-1" "Xtro\dhx29, Xtro\dhx57, Xtro\dhx30, Xtro\dhx36, Xtro\tdrd9, Xtro\ythdc2, Xtro\dhx9" "Mmus\Dhx9, Mmus\Dhx36, Mmus\Dhx57, Mmus\Tdrd9, Mmus\Dhx29, Mmus\Ythdc2, Mmus\Dhx30" "Hsap\DHX30, Hsap\YTHDC2, Hsap\TDRD9, Hsap\DHX36, Hsap\DHX9, Hsap\DHX57, Hsap\DHX29" viable FBgn0034829 CG9899 - http://flybase.org/reports/FBgn0034829 protein_coding_gene SH2 domain binding ; GO:0042169 | inferred from sequence or structural similarity with MGI:MGI:109345 RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000361535 "regulation of histone H3-K4 methylation ; GO:0051569 | inferred from biological aspect of ancestor with PANTHER:PTN000361535 regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000361535 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with MGI:MGI:109345" transcriptionally active chromatin ; GO:0035327 | inferred from sequence or structural similarity with MGI:MGI:109345 Cdc73/Paf1 complex ; GO:0016593 | inferred from biological aspect of ancestor with PANTHER:PTN000361535 CG9899 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR031101:RNA polymerase-associated protein Ctr9" CG9899 11-Aug-17 DroID_v2017_08 Drer\ctr9 Scer\CTR9 Cele\ctr-9 Xtro\ctr9 Mmus\Ctr9 "Hsap\CTR9, Hsap\TTC21B" FBgn0264408 FCE-A - http://flybase.org/reports/FBgn0264408 gene - - - FCE-A - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,somatic clone" FBgn0266304 CR44969 - http://flybase.org/reports/FBgn0266304 non_protein_coding_gene - - - CR44969 - CR44969 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061471 5.8SrRNA 5.8SrRNA http://flybase.org/reports/FBgn0061471 rRNA_gene - - - "5.8S rRNA, 5.8SRNA, 5.8SrRNA, 5.8S" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001485 l(1)10Ae lethal (1) 10Ae http://flybase.org/reports/FBgn0001485 - gene - - - "l(1)BP7, 8, L8, l(1)8, l(1)L8, l(1)G10, l(1)10Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "some die during larval stage,lethal,recessive,partially lethal - majority die,heat sensitive,lethal - all die before end of larval stage,cold sensitive,dominant" FBgn0037841 CG4565 - http://flybase.org/reports/FBgn0037841 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007728 histone methyltransferase activity (H3-K36 specific) ; GO:0046975 | inferred from sequence or structural similarity with SGD:S000003704 histone lysine methylation ; GO:0034968 | inferred from electronic annotation with InterPro:IPR007728 histone methylation ; GO:0016571 | inferred from sequence or structural similarity with SGD:S000003704 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000003704 CG4565 "IPR001214:SET domain, IPR007728:Pre-SET domain, IPR003616:Post-SET domain" CG4565 11-Aug-17 DroID_v2017_08 "Drer\ehmt1a, Drer\ehmt1b, Drer\setmar, Drer\suv39h1a, Drer\suv39h1b, Drer\ehmt2, Drer\trabd" Scer\SET2 "Cele\fbxa-167, Cele\set-13, Cele\set-15, Cele\set-25, Cele\F38A5.2, Cele\set-23, Cele\fbxa-171" "Xtro\suv39h2, Xtro\setmar, Xtro\trabd, Xtro\ehmt2, Xtro\ehmt1" "Mmus\Trabd, Mmus\Setmar, Mmus\Ehmt2, Mmus\Ehmt1, Mmus\Suv39h1, Mmus\Suv39h2" "Hsap\LOC100506127, Hsap\SUV39H2, Hsap\EHMT2, Hsap\SETMAR, Hsap\SUV39H1, Hsap\TRABD, Hsap\EHMT1" "viable,fertile" FBgn0058156 CG40156 - http://flybase.org/reports/FBgn0058156 protein_coding_gene - - - CG40156 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029843 Nep1 Neprilysin 1 http://flybase.org/reports/FBgn0029843 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497 metallopeptidase activity ; GO:0008237 | inferred from sequence model" proteolysis ; GO:0006508 | inferred from sequence or structural similarity with HGNC:7154 proteolysis ; GO:0006508 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence model "CG5894, dNEP1, NEP, CG5914, CG5905, Nep1, DmeNEP1, NEP1, nep1" "IPR018497:Peptidase M13, C-terminal domain, IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR030082:Neprilysin-21" CG5905 11-Aug-17 DroID_v2017_08 "Drer\phex, Drer\mmel1, Drer\ece1, Drer\ece2b" - "Cele\nep-11, Cele\nep-2, Cele\nep-19, Cele\nep-21, Cele\nep-22, Cele\nep-1" "Xtro\ece1, Xtro\ecel1, Xtro\ece2, Xtro\mmel1" "Mmus\Mme, Mmus\Mmel1, Mmus\Ece1, Mmus\Ece2, Mmus\Phex, Mmus\Kel, Mmus\Ecel1" "Hsap\ECE2, Hsap\MME, Hsap\ECEL1, Hsap\ECE1, Hsap\PHEX, Hsap\KEL, Hsap\MMEL1" "visible,lethal,viable" wing FBgn0065754 l(2)SH0490 lethal (2) SH0490 http://flybase.org/reports/FBgn0065754 gene - - - l(2)SH0490 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262359 CG43057 - http://flybase.org/reports/FBgn0262359 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43057 - CG43057 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005004 dcm dark carmine http://flybase.org/reports/FBgn0005004 - gene - - - "d-cm, dcm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,recessive" pigment cell FBgn0028015 l(3)S106605 lethal (3) S106605 http://flybase.org/reports/FBgn0028015 gene - - - "1066/05, l(3)S106605" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0002348 l(3)87Cd lethal (3) 87Cd http://flybase.org/reports/FBgn0002348 - gene - - - "l(3)SzD, l(3)m114-SzD, l(3)87Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,partially lethal - majority die" FBgn0029119 Su(Sxl[fs])X2 Su(Sxl[fs])X2 http://flybase.org/reports/FBgn0029119 gene - - - Su(Sxl[fs])X2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036206 CG5964 - http://flybase.org/reports/FBgn0036206 protein_coding_gene - establishment of epithelial cell polarity ; GO:0090162 | inferred from electronic annotation with InterPro:IPR033561 cilium assembly ; GO:0060271 | inferred from electronic annotation with InterPro:IPR033561 ciliary transition fiber ; GO:0097539 | inferred from electronic annotation with InterPro:IPR033561 CG5964 IPR033561:Fas-binding factor 1 CG5964 11-Aug-17 DroID_v2017_08 Drer\LOC100535852 - Cele\dyf-19 - Mmus\Fbf1 Hsap\FBF1 "partially lethal - majority die,some die during pupal stage" FBgn0011061 l(1)Q14 lethal (1) Q14 http://flybase.org/reports/FBgn0011061 FBgn0010210 gene - - - l(1)Q14 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264449 CG43867 - http://flybase.org/reports/FBgn0264449 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available "cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299, InterPro:IPR000857 cellular_component ; GO:0005575 | no biological data available" "CG43867, CG12467, CG42248, EG:34F3.2, EG:34F3.1, CG14633, CG14632" "IPR029071:Ubiquitin-related domain, IPR019748:FERM central domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR000857:MyTH4 domain, IPR019749:Band 4.1 domain, IPR000299:FERM domain" CG43867 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-18i17.2, Drer\plekhh2, Drer\plekhh1" - Cele\max-1 Xtro\plekhh2 "Mmus\Plekhh2, Mmus\Plekhh3, Mmus\Plekhh1" "Hsap\PLEKHH1, Hsap\PLEKHH3, Hsap\PLEKHH2" FBgn0023087 en::h en::h http://flybase.org/reports/FBgn0023087 - engineered_fusion_gene - - - en::h - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female" FBgn0051832 CG31832 - http://flybase.org/reports/FBgn0051832 protein_coding_gene transmembrane receptor protein tyrosine kinase activator activity ; GO:0030297 | inferred from sequence or structural similarity with HGNC:487 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with HGNC:487 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:487 "BG:DS00929.7, DS00929.7, CG31832, AAF44911, FBpp0080285" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR020837:Fibrinogen, conserved site, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG31832 11-Aug-17 DroID_v2017_08 "Drer\fgg, Drer\fgb, Drer\mfap4, Drer\LOC555374, Drer\zgc:173915, Drer\si:ch1073-110a20.2, Drer\fibcd1, Drer\angpt2a, Drer\angptl7, Drer\si:dkeyp-51b7.3, Drer\angptl5, Drer\angpt4, Drer\angpt1, Drer\si:ch211-157b11.8, Drer\angptl6, Drer\zgc:171687, Drer\fga, Drer\angptl4, Drer\tnw, Drer\zgc:194887, Drer\tnr, Drer\angptl1a, Drer\angptl2b, Drer\wu:fj11g02, Drer\si:zfos-2330d3.1, Drer\angptl2a, Drer\tnc, Drer\si:ch1073-110a20.1, Drer\si:zfos-2330d3.3, Drer\si:ch211-203k16.3, Drer\si:zfos-2330d3.8, Drer\fgl2b, Drer\angptl3, Drer\si:ch1073-110a20.3, Drer\fgl1, Drer\LOC100007488, Drer\zmp:0000000846, Drer\angpt2b, Drer\tnxba, Drer\si:ch211-287a12.9, Drer\fgl2a, Drer\si:zfos-2330d3.6" - "Cele\K10D3.4, Cele\T15B7.1, Cele\Y69H2.10, Cele\ZC504.1, Cele\Y26D4A.12, Cele\C08G9.2, Cele\Y69H2.3, Cele\Y43C5A.2, Cele\W05B2.2, Cele\ensh-1" "Xtro\fgl1, Xtro\angpt4, Xtro\angptl3, Xtro\fgg, Xtro\tnc, Xtro\fibcd1, Xtro\fcn2, Xtro\angptl2, Xtro\fga, Xtro\fcn1, Xtro\tnxb, Xtro\mfap4, Xtro\angptl4, Xtro\tnr, Xtro\LOC100497330, Xtro\fgb, Xtro\tnn, Xtro\fcn3, Xtro\angpt1, Xtro\LOC100491105, Xtro\angptl5, Xtro\LOC100488177, Xtro\fgl2" "Mmus\Fgb, Mmus\Angptl2, Mmus\Angpt2, Mmus\Fcna, Mmus\Angpt1, Mmus\Fgl1, Mmus\Angptl7, Mmus\Angptl3, Mmus\Angptl4, Mmus\Angptl1, Mmus\Mfap4, Mmus\Angptl6, Mmus\Tnn, Mmus\Tnr, Mmus\Fcnb, Mmus\Fgg, Mmus\Tnc, Mmus\Fgl2, Mmus\Angpt4, Mmus\Fibcd1, Mmus\Fga, Mmus\Tnxb" "Hsap\TNN, Hsap\FGL2, Hsap\FIBCD1, Hsap\ANGPTL7, Hsap\FGB, Hsap\ANGPTL3, Hsap\TNR, Hsap\TNC, Hsap\FCN3, Hsap\ANGPTL4, Hsap\ANGPT1, Hsap\FCN1, Hsap\FGG, Hsap\FCN2, Hsap\ANGPTL5, Hsap\ANGPTL2, Hsap\ANGPT4, Hsap\ANGPTL1, Hsap\FGL1, Hsap\MFAP4, Hsap\ANGPTL6, Hsap\FGA, Hsap\TNXB, Hsap\ANGPT2" FBgn0259856 Su(Ste):CR42425 Su(Ste):CR42425 http://flybase.org/reports/FBgn0259856 non_protein_coding_gene - - - "Su(Ste):CR42425, CR42425" - CR42425 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000944 fs(2)A14 female sterile (2) A14 http://flybase.org/reports/FBgn0000944 - gene - - - fs(2)A14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect,mitotic cell cycle defective" "female reproductive system,maternal effect,spindle | maternal effect" FBgn0016785 anon-98EFa anon-98EFa http://flybase.org/reports/FBgn0016785 - gene - - - anon-98EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027532 CG7139 - http://flybase.org/reports/FBgn0027532 FBgn0062025 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:LD21293, anon-WO0118547.415, CG7139, mdcds_30855" "IPR002625:Smr domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013899:Domain of unknown function DUF1771" CG7139 11-Aug-17 DroID_v2017_08 "Drer\cnp, Drer\n4bp2l2, Drer\n4bp2" "Scer\CUE2, Scer\YPL199C" Cele\F26A1.14 Xtro\n4bp2l1 "Mmus\N4bp2l2, Mmus\N4bp2l1, Mmus\N4bp2" "Hsap\CNP, Hsap\N4BP2L1, Hsap\N4BP2L2, Hsap\N4BP2" viable FBgn0002287 l(3)73Bc lethal (3) 73Bc http://flybase.org/reports/FBgn0002287 - gene - - - "l(3)std5, l(3)73Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0038435 Gyc89Da Guanylyl cyclase at 89Da http://flybase.org/reports/FBgn0038435 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR011644 guanylate cyclase activity ; GO:0004383 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:Q8INF0 guanylate cyclase activity ; GO:0004383 | non-traceable author statement "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from direct assay response to reactive oxygen species ; GO:0000302 | inferred from direct assay response to hypoxia ; GO:0001666 | inferred from mutant phenotype" "guanylate cyclase complex, soluble ; GO:0008074 | inferred from direct assay guanylate cyclase complex, soluble ; GO:0008074 | inferred from sequence or structural similarity guanylate cyclase complex, soluble ; GO:0008074 | inferred by curator from GO:0004383 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924" "CG14885, GYCb, Gyc-89Da, Gyc89Da" "IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR011644:Heme-NO binding, IPR024096:NO signalling/Golgi transport ligand-binding domain, IPR029787:Nucleotide cyclase, IPR011645:Haem NO binding associated" CG14885 11-Aug-17 DroID_v2017_08 "Drer\gucy1b3, Drer\gucy1a2, Drer\gucy1b2, Drer\gucy1a3" - "Cele\gcy-34, Cele\gcy-37, Cele\gcy-35, Cele\gcy-31, Cele\gcy-36, Cele\gcy-32, Cele\gcy-33" "Xtro\gucy1b3, Xtro\gucy1a2" "Mmus\Gucy1b2, Mmus\Gucy1b3, Mmus\Gucy1a2, Mmus\Gucy1a3" "Hsap\GUCY1A3, Hsap\GUCY1A2, Hsap\GUCY1B3" "stress response defective,viable,fertile,taste perception defective" FBgn0039241 CG11089 - http://flybase.org/reports/FBgn0039241 protein_coding_gene IMP cyclohydrolase activity ; GO:0003937 | inferred from electronic annotation with InterPro:IPR002695 phosphoribosylaminoimidazolecarboxamide formyltransferase activity ; GO:0004643 | inferred from electronic annotation with InterPro:IPR002695 purine nucleotide biosynthetic process ; GO:0006164 | inferred from electronic annotation with InterPro:IPR002695 wound healing ; GO:0042060 | inferred from mutant phenotype - "153761_at, CT30991, BEST:GH11240, CG11089, atic" "IPR002695:AICARFT/IMPCHase bienzyme, IPR011607:Methylglyoxal synthase-like domain, IPR024051:AICAR transformylase domain, IPR016193:Cytidine deaminase-like" CG11089 11-Aug-17 DroID_v2017_08 Drer\atic "Scer\ADE17, Scer\ADE16" Cele\atic-1 Xtro\atic Mmus\Atic Hsap\ATIC viable FBgn0028063 l(3)S092416 lethal (3) S092416 http://flybase.org/reports/FBgn0028063 gene - - - "0924/16, l(3)S092416" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264830 CG44038 - http://flybase.org/reports/FBgn0264830 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44038 - CG44038 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263569 mir-4968 mir-4968 stem loop http://flybase.org/reports/FBgn0263569 miRNA_gene - - - "mir-4968, dme-mir-4968, CR43554" - CR43554 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031516 CG9663 - http://flybase.org/reports/FBgn0031516 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 CG9663 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG9663 11-Aug-17 DroID_v2017_08 "Drer\abcg2b, Drer\abcg4a, Drer\abcg8, Drer\abcg1, Drer\abcg4b, Drer\abcg5, Drer\abcg2a" "Scer\ADP1, Scer\PDR10, Scer\YOL075C" Cele\abch-1 "Xtro\abcg8, Xtro\abcg5" "Mmus\Abcg5, Mmus\Abcg1, Mmus\Abcg4, Mmus\Abcg2, Mmus\Abcg8, Mmus\Abcg3" "Hsap\ABCG8, Hsap\ABCG1, Hsap\ABCG4, Hsap\ABCG5" "viable,fertile" FBgn0011897 tRNA:Lys-CTT-1-11 transfer RNA:Lysine-CTT 1-11 http://flybase.org/reports/FBgn0011897 "FBgn0011886, FBgn0050520, FBgn0060178" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "tRNA[Lys][[2]], AE002787.trna56-LysCTT, tRNA:K2, tRNA:K:CTT:AE002787-b, tRNA:lys2:56EF, CR30520, chr2R.trna40-LysCTT, tRNA-Lys-CTT-1-11, tRNA:Lys-CTT-1-11, tRNA:K2:56EF, AAG" - CR30520 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086908 egg eggless http://flybase.org/reports/FBgn0086908 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007728 histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | inferred from direct assay double-stranded methylated DNA binding ; GO:0010385 | inferred from direct assay histone-lysine N-methyltransferase activity ; GO:0018024 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with spir inferred from physical interaction with usp inferred from physical interaction with ctp inferred from physical interaction with Ubc10 inferred from physical interaction with CG14820 inferred from physical interaction with AMPdeam inferred from physical interaction with FLYBASE:SEinferred from reviewed computational analysis; FB:FBgn0263006 inferred from physical interaction with Zasp52 inferred from physical interaction with Mcr histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with Pof "histone H3-K9 methylation ; GO:0051567 | inferred from direct assay oogenesis ; GO:0048477 | inferred from direct assay instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype DNA hypermethylation ; GO:0044026 | inferred from mutant phenotype negative regulation of gene expression, epigenetic ; GO:0045814 | inferred from direct assay regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype regulation of gene expression, epigenetic ; GO:0040029 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype histone H3-K9 methylation ; GO:0051567 | inferred from mutant phenotype negative regulation of transcription involved in meiotic cell cycle ; GO:0051038 | inferred from mutant phenotype positive regulation of methylation-dependent chromatin silencing ; GO:0090309 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype" polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay chromocenter ; GO:0010369 | colocalizes_with inferred from direct assay "DmSetdb1, Eggless, CG30426, CG12196, AAF47268 Dm, BcDNA:AT13877, CG30422, egg, Dm-setdb1, Dmsetdb1, dSETDB1, dEset, Egg, SetDB1, SETDB1, dsetdb1, dSetdb1, AAM70794, EGG, Setdb1, Egg/dSETDB1" "IPR007728:Pre-SET domain, IPR001214:SET domain, IPR003616:Post-SET domain, IPR001739:Methyl-CpG DNA binding, IPR016177:DNA-binding domain" CG12196 11-Aug-17 DroID_v2017_08 "Drer\setdb1a, Drer\ash1l, Drer\setdb2, Drer\setdb1b" Scer\SET2 "Cele\set-6, Cele\set-16, Cele\met-2" "Xtro\setdb2, Xtro\setdb1" "Mmus\Setdb2, Mmus\Setdb1, Mmus\Ash1l" "Hsap\ASH1L, Hsap\SETDB1, Hsap\SETDB2" DRSC22534 I 1.917147673 1.450678183 -0.401585128 1.390188247 -0.052668166 -0.116368872 FBgn0065193 l(2)SH2326 lethal (2) SH2326 http://flybase.org/reports/FBgn0065193 gene - - - "l(2)SH2326, l(2)SH2 2326" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051897 CG31897 - http://flybase.org/reports/FBgn0051897 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs30d08, CG31897" - CG31897 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0022751 anon-B3 anon-B3 http://flybase.org/reports/FBgn0022751 - gene - - - "B3, anon-B3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043533 Obp56f Odorant-binding protein 56f http://flybase.org/reports/FBgn0043533 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "56f, Obp-d, anon-AE003794.1, CG30450, Obp56f, DmelObp56f" IPR006170:Pheromone/general odorant binding protein CG30450 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC22270 I -0.8604428 -2.877549169 -0.176850827 0.427165702 0.289168331 -0.397774086 FBgn0266166 CR44872 - http://flybase.org/reports/FBgn0266166 non_protein_coding_gene - - - CR44872 - CR44872 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026396 Or22c Odorant receptor 22c http://flybase.org/reports/FBgn0026396 - protein_coding_gene olfactory receptor activity ; GO:0004984 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "22c, DOR16, CG15377, 22C.1, DOR22C.1, Or22C.1, Or22c" "IPR004117:Olfactory receptor, insect" CG15377 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0266549 CR45102 - http://flybase.org/reports/FBgn0266549 non_protein_coding_gene - - - "CR45102, RE64691" - CR45102 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266009 CR44782 - http://flybase.org/reports/FBgn0266009 non_protein_coding_gene - - - "CR44782, lincRNA.380" - CR44782 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038842 hdly hadley http://flybase.org/reports/FBgn0038842 protein_coding_gene - "negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype" - "CG5630, hdly" - CG5630 11-Aug-17 DroID_v2017_08 - - - - - - "mating behavior defective,female limited,female semi-fertile" FBgn0034924 CG17658 - http://flybase.org/reports/FBgn0034924 protein_coding_gene - - - CG17658 "IPR002893:Zinc finger, MYND-type" CG17658 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040996 CG12617 - http://flybase.org/reports/FBgn0040996 protein_coding_gene - - - "38C.31, CG12617" - CG12617 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-85n7.8, Drer\cox8b" - - - "Mmus\Cox8b, Mmus\Cox8a" Hsap\COX8A viable FBgn0003014 osh outshifted http://flybase.org/reports/FBgn0003014 - gene - - - osh - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive,eye color defective,body color defective" "wing,eye" FBgn0267944 CR46224 - http://flybase.org/reports/FBgn0267944 non_protein_coding_gene - - - "CR46224, lincRNA.705" - CR46224 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052939 CG32939 - http://flybase.org/reports/FBgn0052939 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32939 IPR016181:Acyl-CoA N-acyltransferase CG32939 11-Aug-17 DroID_v2017_08 - - - Xtro\cml - - FBgn0266975 CR45426 - http://flybase.org/reports/FBgn0266975 non_protein_coding_gene - - - CR45426 - CR45426 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003945 Udg Uracil DNA glycosylase http://flybase.org/reports/FBgn0003945 - gene uracil DNA N-glycosylase activity ; GO:0004844 | inferred from direct assay - - "Udg, UDG" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037601 Cyp313b1 Cyp313b1 http://flybase.org/reports/FBgn0037601 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" - "313b1, CG9716, Cyp313b1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG9716 11-Aug-17 DroID_v2017_08 "Drer\cyp4f3, Drer\LOC100329425, Drer\cyp46a1.4, Drer\cyp46a1.3, Drer\zgc:123299, Drer\cyp26a1, Drer\cyp4t8, Drer\cyp4v7, Drer\cyp4v8, Drer\cyp26c1, Drer\cyp46a1.2, Drer\cyp26b1, Drer\cyp20a1, Drer\cyp46a1.1, Drer\cyp19a1a, Drer\cyp19a1b" "Scer\ERG11, Scer\ERG5, Scer\DIT2" "Cele\cyp-25A1, Cele\cyp-25A2" "Xtro\LOC100488227, Xtro\cyp4b1, Xtro\cyp26c1, Xtro\LOC100487918, Xtro\cyp4f22, Xtro\cyp20a1, Xtro\cyp4v2, Xtro\cyp26b1, Xtro\cyp26a1, Xtro\cyp4b1.2, Xtro\cyp19a1, Xtro\mgc108213, Xtro\cyp4f2" "Mmus\Cyp4f15, Mmus\Cyp4f16, Mmus\Cyp26b1, Mmus\Cyp4a12b, Mmus\Cyp20a1, Mmus\Cyp4a10, Mmus\Cyp26a1, Mmus\Cyp4a14, Mmus\Cyp4b1, Mmus\Cyp4f39, Mmus\Cyp4f37, Mmus\Cyp4a12a, Mmus\Cyp4x1, Mmus\Cyp46a1, Mmus\Cyp4f40, Mmus\Cyp26c1, Mmus\Cyp4f13, Mmus\Cyp4a32, Mmus\Cyp4f17, Mmus\Cyp19a1, Mmus\Cyp4f14, Mmus\Cyp4f18, Mmus\Cyp4a31, Mmus\Cyp4v3" "Hsap\CYP46A1, Hsap\CYP4F2, Hsap\CYP4F12, Hsap\CYP4F11, Hsap\CYP20A1, Hsap\CYP4X1, Hsap\CYP4A22, Hsap\CYP26B1, Hsap\CYP26A1, Hsap\CYP4F3, Hsap\CYP19A1, Hsap\CYP26C1, Hsap\CYP4V2, Hsap\CYP4B1, Hsap\CYP4F22, Hsap\CYP4A11, Hsap\CYP4Z1" viable FBgn0262282 mir-984 mir-984 stem loop http://flybase.org/reports/FBgn0262282 miRNA_gene - - - "miR-984, mir-984, CR42989, dme-mir-984, dme-miR-984" - CR42989 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,visible,lethal - all die before end of larval stage,some die during larval stage" wing FBgn0037643 skap skpA associated protein http://flybase.org/reports/FBgn0037643 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011761, InterPro:IPR013815, InterPro:IPR013816 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011761 succinate-CoA ligase (ADP-forming) activity ; GO:0004775 | inferred from sequence or structural similarity with UniProtKB:Q9P2R7" sperm individualization ; GO:0007291 | inferred from mutant phenotype regulation of centrosome duplication ; GO:0010824 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043280 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:Q9P2R7 mitochondrion ; GO:0005739 | inferred from direct assay Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from direct assay succinate-CoA ligase complex (ADP-forming) ; GO:0009361 | inferred from sequence or structural similarity with UniProtKB:Q9P2R7 centrosome ; GO:0005813 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "skap, CG11963, Skap, SkAP, CGI 1963, A-Sbeta" "IPR005809:Succinate--CoA synthetase, beta subunit, IPR005811:ATP-citrate lyase/succinyl-CoA ligase, IPR011761:ATP-grasp fold, IPR013650:ATP-grasp fold, succinyl-CoA synthetase-type, IPR016102:Succinyl-CoA synthetase-like, IPR017866:Succinyl-CoA synthetase, beta subunit, conserved site, IPR034723:Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, IPR013815:ATP-grasp fold, subdomain 1" CG11963 11-Aug-17 DroID_v2017_08 "Drer\sucla2, Drer\suclg2" Scer\LSC2 "Cele\sucg-1, Cele\suca-1" "Xtro\suclg2, Xtro\sucla2" "Mmus\Sucla2, Mmus\Suclg2" "Hsap\SUCLG2, Hsap\SUCLA2" "partially lethal - majority die,viable" FBgn0000839 fs(1)M26 female sterile (1) M26 http://flybase.org/reports/FBgn0000839 - gene - - - fs(1)M26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" FBgn0015298 Srp19 Signal recognition particle protein 19 http://flybase.org/reports/FBgn0015298 - protein_coding_gene 7S RNA binding ; GO:0008312 | inferred from biological aspect of ancestor with PANTHER:PTN000425879 "SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition ; GO:0006617 | inferred from biological aspect of ancestor with PANTHER:PTN000425880 SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616 | inferred from biological aspect of ancestor with PANTHER:PTN000425880" "signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from biological aspect of ancestor with PANTHER:PTN000425880" "CG4457, srp19, SRP19, Srp19" "IPR002778:Signal recognition particle, SRP19 subunit" CG4457 11-Aug-17 DroID_v2017_08 Drer\srp19 Scer\SEC65 Cele\F37F2.2 Xtro\srp19 Mmus\Srp19 Hsap\SRP19 embryonic stage -- adult stage FBgn0053454 CG33454 - http://flybase.org/reports/FBgn0053454 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33454 IPR010512:Protein of unknown function DUF1091 CG33454 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0266700 CR45190 - http://flybase.org/reports/FBgn0266700 non_protein_coding_gene - - - CR45190 - CR45190 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023180 Orc6 Origin recognition complex subunit 6 http://flybase.org/reports/FBgn0023180 - protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from direct assay DNA replication origin binding ; GO:0003688 | inferred from biological aspect of ancestor with PANTHER:PTN000333607 GTPase activator activity ; GO:0005096 | inferred from direct assay DNA replication ; GO:0006260 | inferred from mutant phenotype septin cytoskeleton organization ; GO:0032185 | inferred from direct assay positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from direct assay origin recognition complex ; GO:0000808 | inferred from direct assay plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay septin complex ; GO:0031105 | colocalizes_with inferred from direct assay septin cytoskeleton ; GO:0032156 | inferred from direct assay nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay "rDmORC, ORC6, ORC, DmORC 6, DmORC6, CG1584, Orc6, orc6" "IPR008721:Origin recognition complex, subunit 6, IPR020529:Origin recognition complex, subunit 6, metazoa/plant" CG1584 11-Aug-17 DroID_v2017_08 Drer\orc6 - "Cele\nhr-190, Cele\fbxb-104" Xtro\orc6 Mmus\Orc6 Hsap\ORC6 " embryonic stage , embryonic stage&&larval stage " "neuroanatomy defective,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during third instar larval stage,increased cell death,lethal,viable,visible" "embryonic/larval optic lobe,imaginal disc,presumptive embryonic salivary gland,embryonic/larval brain,trichogen cell" DRSC07497 I 1.734801406 -0.126049285 -0.374049829 0.284810577 -0.257553232 -0.785302697 FBgn0011963 tRNA:Arg-ACG-1-6 transfer RNA:Arginine-ACG 1-6 http://flybase.org/reports/FBgn0011963 "FBgn0003758, FBgn0011947, FBgn0051584, FBgn0060093" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "tRNA[arg], tRNA[Arg][[2]], AE002708.trna66-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002708-e, CR31584, tRNA:arg2:84Fe, chr3R.trna72-ArgACG, tRNA-Arg-ACG-1-6, tRNA:Arg-ACG-1-6, tRNA:R2:84Fe, CGU" - CR31584 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024682 l(1)LefEM2 lethal (1) LefEM2 http://flybase.org/reports/FBgn0024682 - gene - - - "EM2, l(1)LefEM2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013691 mt:tRNA:Asp-GTC mitochondrial transfer RNA:Aspartic acid-GTC http://flybase.org/reports/FBgn0013691 FBgn0002867 tRNA_gene - - - "CR34071, mtdbD00006300, mt:tRNA:Asp-GTC, mt:tRNA:D" - CR34071 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037657 hyx hyrax http://flybase.org/reports/FBgn0037657 protein_coding_gene "transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 transcription factor binding ; GO:0008134 | inferred from physical interaction with ci" "positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype inferred from genetic interaction with ptc inferred from genetic interaction with ci imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 histone modification ; GO:0016570 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex ; GO:0034402 | inferred from biological aspect of ancestor with PANTHER:PTN000279609" nucleus ; GO:0005634 | inferred from direct assay Cdc73/Paf1 complex ; GO:0016593 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with ci "hyx, CG11990, Hyx, Cdc73, hyx/CDC73" "IPR007852:Cdc73/Parafibromin, IPR031336:Cell division control protein 73, C-terminal, IPR032041:Paf1 complex subunit Cdc73, N-terminal domain" CG11990 11-Aug-17 DroID_v2017_08 Drer\cdc73 Scer\CDC73 Cele\cdc-73 Xtro\cdc73 Mmus\Cdc73 Hsap\CDC73 "visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,cell lethalcell lethal,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal" "wing,leg,wing margin,somatic clone,wing vein,macrochaeta,eye" DRSC14462 IEK 3.942875649 2.937888866 2.482426048 0.62218994 2.159218666 1.016008489 FBgn0020568 anon-88Ab anon-88Ab http://flybase.org/reports/FBgn0020568 - gene - - - anon-88Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010117 l(1)1 lethal (1) 1 http://flybase.org/reports/FBgn0010117 - gene - - - l(1)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002445 l(3)S2 lethal (3) S2 http://flybase.org/reports/FBgn0002445 - gene - - - l(3)S2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259442 C923 - http://flybase.org/reports/FBgn0259442 gene - - - C923 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing,chaeta,ectopic" FBgn0029727 CG6978 - http://flybase.org/reports/FBgn0029727 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 CG6978 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG6978 11-Aug-17 DroID_v2017_08 "Drer\ppt1, Drer\slc17a8, Drer\slc17a7a, Drer\slc17a6a, Drer\slc17a5, Drer\slc17a6b, Drer\si:ch1073-513e17.1, Drer\slc17a9a" "Scer\TNA1, Scer\DAL5, Scer\THI73, Scer\YIL166C" "Cele\T02B11.6, Cele\F41C3.2, Cele\T22F3.10, Cele\C18D1.2, Cele\T19D12.10, Cele\slc-17.9, Cele\C35A5.3, Cele\C39E9.7, Cele\Y19D10A.5, Cele\T01H3.3, Cele\slc-17.7, Cele\F59A1.13, Cele\F11A5.9, Cele\slc-17.8, Cele\T27D12.1, Cele\F56A4.12, Cele\Y19D10A.11, Cele\C18H9.5, Cele\Y4C6B.3, Cele\Y4C6B.4, Cele\K11G9.5, Cele\M117.1, Cele\H11E01.2, Cele\Y19D10A.4, Cele\slc-17.3, Cele\D1046.4, Cele\slc-17.4, Cele\C01B4.8, Cele\T22F3.8, Cele\T19D12.9, Cele\eat-4, Cele\R10D12.1, Cele\vglu-3, Cele\W04C9.6, Cele\F10C2.7, Cele\slc-17.1, Cele\T28H11.8, Cele\cima-1, Cele\T22F3.7, Cele\slc-17.2, Cele\M162.5, Cele\T22F3.11, Cele\vglu-2, Cele\F44E7.7, Cele\Y15E3A.4, Cele\slc-17.5, Cele\K08C7.1, Cele\C01B4.7, Cele\F56A4.10, Cele\Y51B9A.6, Cele\Y19D10A.8" Xtro\slc17a7 "Mmus\Slc17a6, Mmus\Slc17a4, Mmus\Slc17a7, Mmus\Slc17a5, Mmus\Slc17a3, Mmus\Slc17a8, Mmus\Slc17a1, Mmus\Slc17a2" "Hsap\SLC17A6, Hsap\SLC17A3, Hsap\SLC17A8, Hsap\SLC17A5, Hsap\SLC17A2, Hsap\SLC17A4, Hsap\SLC17A1, Hsap\SLC17A7" viable FBgn0029596 CG14054 - http://flybase.org/reports/FBgn0029596 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT13882, CG14054" - CG14054 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0000845 fs(1)M32 female sterile (1) M32 http://flybase.org/reports/FBgn0000845 - gene - - - fs(1)M32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,rescuable maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,cold sensitive,some die during embryonic stage" egg FBgn0033188 Drat Death resistor Adh domain containing target http://flybase.org/reports/FBgn0033188 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002085 response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern cellular response to ethanol ; GO:0071361 | inferred from mutant phenotype - "Drat, CG1600" "IPR011032:GroES-like, IPR016040:NAD(P)-binding domain, IPR020843:Polyketide synthase, enoylreductase domain" CG1600 11-Aug-17 DroID_v2017_08 "Drer\cryzl1, Drer\vat1, Drer\tp53i3, Drer\rtn4ip1" "Scer\ADH1, Scer\AST2, Scer\YLR460C, Scer\ADH2, Scer\AST1, Scer\YCR102C, Scer\ADH7, Scer\YNL134C, Scer\ADH5, Scer\ADH6, Scer\ADH3, Scer\YIM1" Cele\ZK829.7 "Xtro\rtn4ip1, Xtro\cryzl1, Xtro\vat1, Xtro\vat1l, Xtro\tp53i3" "Mmus\Vat1l, Mmus\Rtn4ip1, Mmus\BC026585, Mmus\Cryzl1, Mmus\Vat1" "Hsap\VAT1, Hsap\CRYZL1, Hsap\VAT1L, Hsap\TP53I3, Hsap\RTN4IP1" viable FBgn0264793 CR44023 - http://flybase.org/reports/FBgn0264793 non_protein_coding_gene - - - CR44023 - CR44023 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004690 ptd parted http://flybase.org/reports/FBgn0004690 - gene - - - ptd - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive,male fertile,viable,female sterile" wing FBgn0066315 APP.s APP.s http://flybase.org/reports/FBgn0066315 gene - - - "APP s, APP.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267114 CR45554 - http://flybase.org/reports/FBgn0267114 non_protein_coding_gene - - - CR45554 - CR45554 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029810 CG12239 - http://flybase.org/reports/FBgn0029810 protein_coding_gene - - - CG12239 - CG12239 11-Aug-17 DroID_v2017_08 - - Cele\Y6B3B.4 Xtro\sclt1 - - viable FBgn0036752 Adgf-A Adenosine deaminase-related growth factor A http://flybase.org/reports/FBgn0036752 protein_coding_gene growth factor activity ; GO:0008083 | inferred from direct assay adenosine deaminase activity ; GO:0004000 | inferred from direct assay adenosine catabolic process ; GO:0006154 | inferred from direct assay hemocyte differentiation ; GO:0042386 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from genetic interaction with bip1 cellular response to sucrose starvation ; GO:0043617 | inferred from mutant phenotype regulation of carbohydrate metabolic process ; GO:0006109 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "ADGF-A, CG5992, ADGDF-A, adgfa, Adgf-A, adgf-a, Adgf-a, AdgfA" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG5992 11-Aug-17 DroID_v2017_08 "Drer\cecr1a, Drer\ada, Drer\cecr1b, Drer\adal" Scer\AAH1 "Cele\C44B7.12, Cele\C06G3.5" "Xtro\ada.2, Xtro\adal, Xtro\ada, Xtro\cecr1" "Mmus\Adal, Mmus\Ada" "Hsap\CECR1, Hsap\ADA, Hsap\ADAL" "melanotic mass phenotype,viable,fertile,lethal - all die before end of larval stage,some die during larval stage,developmental rate defective,lethal" "melanotic mass,embryonic/larval fat body,pupal abdomen,adult abdomen,lamellocyte,crystal cell,embryonic/larval lymph gland,sessile hemocyte,embryonic/larval hemocyte" FBgn0066123 E(sda)L E(sda)L http://flybase.org/reports/FBgn0066123 gene - - - "E(sda)L, Line L" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263662 CR43653 - http://flybase.org/reports/FBgn0263662 non_protein_coding_gene - - - CR43653 - CR43653 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064225 RpL5 Ribosomal protein L5 http://flybase.org/reports/FBgn0064225 protein_coding_gene 5S rRNA binding ; GO:0008097 | inferred from biological aspect of ancestor with PANTHER:PTN000601661 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:P26321 protein binding ; GO:0005515 | inferred from physical interaction with Fmr1 structural constituent of ribosome ; GO:0003735 | non-traceable author statement 5S rRNA binding ; GO:0008097 | non-traceable author statement structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR005484, InterPro:IPR005485 ribosomal large subunit assembly ; GO:0000027 | inferred from sequence or structural similarity with UniProtKB:P26321 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000601661" cytosolic large ribosomal subunit ; GO:0022625 | non-traceable author statement ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG17489, E-2d, yip6, L5, RpL5, dRPL5, M(2)40B, Rpl5, Rp L5" "IPR025607:Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal, IPR005485:Ribosomal protein L5 eukaryotic/L18 archaeal" CG17489 11-Aug-17 DroID_v2017_08 "Drer\rpl5b, Drer\rpl5a" Scer\RPL5 Cele\rpl-5 Xtro\rpl5 Mmus\Rpl5 Hsap\RPL5 "lethal - all die before end of larval stage,some die during larval stage,small body,Minute,dominant,developmental rate defective,increased cell size,decreased cell number,recessive,size defective" "chaeta,macrochaeta,adult heart" DRSC03801 IEK -2.251217493 -1.894209947 0.188390433 -5.508396791 3.176023874 1.939396561 FBgn0010174 RpA-30 Replication Protein A 30 http://flybase.org/reports/FBgn0010174 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay DNA-dependent DNA replication ; GO:0006261 | inferred from direct assay DNA replication factor A complex ; GO:0005662 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DmRPA, RPA30, RPA, RP-A, DmRP-A, dRP-A, DRP-A, D-SSB, Ssb-30, RpA-30, RPA 30 kDa" - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage FBgn0031398 CG10880 - http://flybase.org/reports/FBgn0031398 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10880 IPR016024:Armadillo-type fold CG10880 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,viable" FBgn0026190 PH4alphaMP prolyl-4-hydroxylase-alpha MP http://flybase.org/reports/FBgn0026190 FBgn0015713 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "DM59D7T, 59D7T, ESTS:59D7T, CG9726, PH4alphaMP" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG9726 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\p4ha1a, Drer\p4htm, Drer\zgc:158254, Drer\p4ha3, Drer\zgc:152670, Drer\p4ha2" - "Cele\dpy-18, Cele\C14E2.4, Cele\Y43F8B.19, Cele\phy-3, Cele\phy-4, Cele\phy-2" "Xtro\p4ha3, Xtro\p4ha1, Xtro\p4ha2" "Mmus\P4ha2, Mmus\P4ha3, Mmus\P4ha1, Mmus\P4htm" "Hsap\P4HA3, Hsap\P4HA2, Hsap\P4HTM, Hsap\P4HA1" "viable,fertile" FBgn0262150 CG42876 - http://flybase.org/reports/FBgn0262150 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42876 - CG42876 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003706 tipA temperature-induced paralytic A http://flybase.org/reports/FBgn0003706 - gene - - - tipA - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,heat sensitive" FBgn0015444 l(1)7Da lethal (1) 7Da http://flybase.org/reports/FBgn0015444 - gene - - - l(1)7Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040799 CG13051 - http://flybase.org/reports/FBgn0040799 protein_coding_gene - - - CG13051 - CG13051 11-Aug-17 DroID_v2017_08 - - Cele\mltn-9 - - - FBgn0001846 l(1)ts3733 lethal (1) ts3733 http://flybase.org/reports/FBgn0001846 - gene - - - l(1)ts3733 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0060392 l(3)S133610 lethal (3) S133610 http://flybase.org/reports/FBgn0060392 gene - - - "1336/10, l(3)S133610" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266262 CR44957 - http://flybase.org/reports/FBgn0266262 non_protein_coding_gene - - - CR44957 - CR44957 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263746 CR43671 - http://flybase.org/reports/FBgn0263746 pseudogene_attribute - - - "CR43671, CG31782" - CR43671 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260488 l(3)1025 - http://flybase.org/reports/FBgn0260488 gene - fasciculation of sensory neuron axon ; GO:0097155 | inferred from mutant phenotype - l(3)1025 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective dendritic arborizing neuron FBgn0053721 CG33721 - http://flybase.org/reports/FBgn0053721 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR33721, CG33721" IPR010512:Protein of unknown function DUF1091 CG33721 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0010680 l(2)s1878 lethal (2) s1878 http://flybase.org/reports/FBgn0010680 - gene - - - l(2)s1878 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013248 E(var)3-13 E(var)3-13 http://flybase.org/reports/FBgn0013248 - gene - - - "E-var(3)13, E(var)3-13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0005328 P37 P37 http://flybase.org/reports/FBgn0005328 - gene - - - P37 - - 11-Aug-17 DroID_v2017_08 - - - - - - "optomotor response defective,phototaxis defective,flight defective,behavior defective" FBgn0040162 l(1)G0442 lethal (1) G0442 http://flybase.org/reports/FBgn0040162 gene - - - l(1)G0442 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0027548 nito spenito http://flybase.org/reports/FBgn0027548 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity nucleic acid binding ; GO:0003676 | inferred from biological aspect of ancestor with PANTHER:PTN000573351 "positive regulation of gene expression ; GO:0010628 | inferred from genetic interaction with Hipk mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000573351 wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype negative regulation of stem cell differentiation ; GO:2000737 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with arm inferred from genetic interaction with hid inferred from genetic interaction with wg compound eye development ; GO:0048749 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "dOTT, CG2910, Dm44A/spenito, cg2910, DmSSp, BcDNA:GH11110, nito, Nito, SSLP" "IPR000504:RNA recognition motif domain, IPR010912:Spen paralogue/orthologue C-terminal, metazoa, IPR012921:Spen paralogue and orthologue SPOC, C-terminal, IPR016194:SPOC-like, C-terminal domain" CG2910 11-Aug-17 DroID_v2017_08 "Drer\rbm15b, Drer\rbm15, Drer\wu:fb69f10, Drer\spen" Scer\NRD1 "Cele\grld-1, Cele\mdt-15" "Xtro\rbm15b, Xtro\rbm15" "Mmus\Spen, Mmus\Rbm15, Mmus\Rbm15b" "Hsap\SPEN, Hsap\RBM15, Hsap\RBM15B" "visible,increased cell death,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "eye photoreceptor cell,ommatidium,rhabdomeresev.PR,eye,posterior,eye disc,ganglion mother cell" DRSC05943 IE 2.044670248 1.27712455 4.466775364 1.017266983 -0.93225926 0.184211916 FBgn0050218 tRNA:iMet-CAT-1-2 transfer RNA:initiator Methionine-CAT 1-2 http://flybase.org/reports/FBgn0050218 tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "CR30218, AE002787.trna54-MetCAT, tRNA:met3:56EF, tRNA:M3:56EF, tRNA:M:CAT:AE002787-e, tRNA[Met-ATG], chr2R.trna37-MetCAT, tRNA-iMet-CAT-1-2, tRNA:iMet-CAT-1-2, tRNA:CR30218" - CR30218 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022124 l(2)k06506 lethal (2) k06506 http://flybase.org/reports/FBgn0022124 - gene - - - l(2)k06506 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260489 l(3)9374 - http://flybase.org/reports/FBgn0260489 gene - fasciculation of sensory neuron axon ; GO:0097155 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - l(3)9374 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,axon,dendrite" FBgn0259927 CG42450 - http://flybase.org/reports/FBgn0259927 protein_coding_gene signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR015898 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR015898 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR000591 heterotrimeric G-protein complex ; GO:0005834 | inferred from electronic annotation with InterPro:IPR015898 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 "CG42450, CG32543, CG7095" "IPR000591:DEP domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR015898:G-protein gamma-like domain, IPR016137:RGS domain, IPR024066:RGS, subdomain 1" CG42450 11-Aug-17 DroID_v2017_08 "Drer\rgs2, Drer\rgs12a, Drer\rgs17, Drer\si:ch211-117l17.5, Drer\rgs16, Drer\grid2ipb, Drer\rgs9b, Drer\rgs3a, Drer\axin1, Drer\si:ch211-117l17.6, Drer\rgs8, Drer\rgs11, Drer\rgs19, Drer\rgs14b, Drer\si:ch211-196h16.12, Drer\rgs1, Drer\rgs6, Drer\rgs14a, Drer\rgs5b, Drer\rgs18, Drer\si:ch211-152p11.4, Drer\rgs4, Drer\rgs9a, Drer\rgs12b, Drer\rgs13, Drer\axin2, Drer\rgs5a" "Scer\RGS2, Scer\SST2" Cele\eat-16 "Xtro\cep112, Xtro\rgs16, Xtro\axin1, Xtro\rgs20, Xtro\rgs5, Xtro\rgs6, Xtro\rgs18, Xtro\xarp, Xtro\rgs3, Xtro\rgs4, Xtro\rgs19, Xtro\rgs1, Xtro\rgs17, Xtro\rgs2, Xtro\rgs10" "Mmus\Rgs12, Mmus\Rgs7, Mmus\Rgs11, Mmus\Rgs10, Mmus\Rgs8, Mmus\Rgs16, Mmus\Rgs2, Mmus\Rgs13, Mmus\Rgs5, Mmus\Rgs17, Mmus\Rgs4, Mmus\Rgs3, Mmus\Axin2, Mmus\Rgs6, Mmus\Rgs1, Mmus\Axin1, Mmus\Rgs14, Mmus\Rgs20, Mmus\Rgs19, Mmus\Rgs18, Mmus\Rgs9" "Hsap\RGS4, Hsap\AXIN1, Hsap\RGS14, Hsap\RGS8, Hsap\RGS3, Hsap\RGS2, Hsap\RGS7, Hsap\RGS9, Hsap\RGS13, Hsap\RGS18, Hsap\RGS5, Hsap\RGS17, Hsap\RGS1, Hsap\RGS10, Hsap\RGS19, Hsap\RGS12, Hsap\RGS16, Hsap\RGS6, Hsap\RGS21, Hsap\RGS11, Hsap\RGS20, Hsap\AXIN2" FBgn0036035 CG18178 - http://flybase.org/reports/FBgn0036035 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000600976 maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000600976 "nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000600976 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000600976" CG18178 IPR000504:RNA recognition motif domain CG18178 11-Aug-17 DroID_v2017_08 Drer\mak16 Scer\MAK16 Cele\C16A3.6 - Mmus\Mak16 Hsap\MAK16 "viable,fertile,visible" trichogen cell FBgn0002303 l(3)84Bc lethal (3) 84Bc http://flybase.org/reports/FBgn0002303 - gene - - - "l(3)84Bb, l(3)84Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020504 C43 C43 http://flybase.org/reports/FBgn0020504 - gene - - - C43 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034197 Cda9 Chitin deacetylase-like 9 http://flybase.org/reports/FBgn0034197 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from electronic annotation with InterPro:IPR002509" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR002509, InterPro:IPR011330" - "DmCDA9, Cda9, CG15918" "IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR002509:NodB homology domain" CG15918 11-Aug-17 DroID_v2017_08 Drer\si:ch211-226m16.2 Scer\CTS2 "Cele\F48E3.8, Cele\lgx-1" - "Mmus\Chil1, Mmus\Chil6, Mmus\Chil5, Mmus\Chil3, Mmus\Chil4, Mmus\Chia1, Mmus\Ovgp1" "Hsap\OVGP1, Hsap\CHIA, Hsap\CHI3L1, Hsap\CHI3L2" viable FBgn0052270 CG32270 - http://flybase.org/reports/FBgn0052270 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP124, CG33161, CG11530, CG32270" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG32270 11-Aug-17 DroID_v2017_08 Drer\si:ch211-165b19.9 - "Cele\svh-1, Cele\try-1" - Mmus\Prss55 - FBgn0038055 trus toys are us http://flybase.org/reports/FBgn0038055 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR007320 "CG5333, trus" "IPR007320:Programmed cell death protein 2, C-terminal" CG5333 11-Aug-17 DroID_v2017_08 "Drer\pdcd2, Drer\pdcd2l" Scer\TSR4 Cele\pdcd-2 "Xtro\pdcd2l, Xtro\pdcd2" "Mmus\Pdcd2l, Mmus\Pdcd2" "Hsap\PDCD2, Hsap\PDCD2L" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0261353 Ccdc56 Coiled-coil domain containing 56 http://flybase.org/reports/FBgn0261353 protein_coding_gene - mitochondrial respiratory chain complex IV biogenesis ; GO:0097034 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "CG42630, Ccdc56, ccdc56, CCDC56, CG7319" - CG42630 11-Aug-17 DroID_v2017_08 "Drer\coa3a, Drer\coa3b" Scer\COA3 Cele\F35D11.5 Xtro\ccdc56 Mmus\Coa3 Hsap\COA3 "viable,dominant,fertile,developmental rate defective,recessive,size defective,lethal - all die before end of larval stage,some die during third instar larval stage,increased cell death" wing disc FBgn0033028 CG11665 - http://flybase.org/reports/FBgn0033028 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG11665 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG11665 11-Aug-17 DroID_v2017_08 "Drer\zgc:114041, Drer\slc16a6b, Drer\slc16a5a, Drer\slc16a13, Drer\si:dkey-246g23.4, Drer\slc16a3, Drer\slc16a9a, Drer\slc16a12a, Drer\si:ch211-234h8.7, Drer\slc16a4, Drer\zgc:165507, Drer\LOC103911912, Drer\slc16a5b, Drer\pdap1a, Drer\slc16a7, Drer\slc16a1b, Drer\slc16a9b, Drer\slc16a1a, Drer\slc16a6a, Drer\slc16a12b" "Scer\MCH5, Scer\ATG22, Scer\MCH2, Scer\MCH4, Scer\ESBP6" "Cele\mct-5, Cele\slcf-1, Cele\mct-6" "Xtro\slc16a5, Xtro\slc16a3, Xtro\slc16a13, Xtro\LOC100491288, Xtro\slc16a6, Xtro\slc16a9, Xtro\slc16a2, Xtro\slc16a7, Xtro\slc16a1, Xtro\slc16a12" "Mmus\Slc16a14, Mmus\Slc16a1, Mmus\Slc16a9, Mmus\Slc16a4, Mmus\Slc16a11, Mmus\Slc16a13, Mmus\Slc16a5, Mmus\Slc16a8, Mmus\Slc16a6, Mmus\Slc16a3, Mmus\Slc16a7, Mmus\Slc16a12" "Hsap\SLC16A6, Hsap\SLC16A3, Hsap\SLC16A1, Hsap\SLC16A11, Hsap\SLC16A8, Hsap\SLC16A7, Hsap\SLC16A14, Hsap\SLC16A12, Hsap\SLC16A9, Hsap\SLC16A13, Hsap\SLC16A4, Hsap\SLC16A5, Hsap\SLC16A10" viable DRSC04853 IK -0.14177668 -1.538081267 -0.117887069 0.37968824 -1.560640833 0.647303658 FBgn0266582 ND-30 NADH dehydrogenase (ubiquinone) 30 kDa subunit http://flybase.org/reports/FBgn0266582 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with HGNC:7710 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O75489 NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from biological aspect of ancestor with PANTHER:PTN000094347 cellular respiration ; GO:0045333 | inferred from biological aspect of ancestor with PANTHER:PTN000094347 reactive oxygen species metabolic process ; GO:0072593 | inferred from sequence or structural similarity with HGNC:7710 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000094349 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O75489 mitochondrion ; GO:0005739 | inferred from direct assay "C-I-NDUFS3, CG12079, CG 12079, NUGM, ND-30, NDUFS3, NDufS3, C-I 30" "IPR001268:NADH:ubiquinone oxidoreductase, 30kDa subunit, IPR010218:NADH dehydrogenase, subunit C, IPR020396:NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site" CG12079 11-Aug-17 DroID_v2017_08 Drer\ndufs3 - Cele\nuo-2 Xtro\ndufs3 Mmus\Ndufs3 "Hsap\NDUFS3, Hsap\PTPMT1" FBgn0259198 CG42302 - http://flybase.org/reports/FBgn0259198 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000451188 protein import into mitochondrial inner membrane ; GO:0045039 | inferred from biological aspect of ancestor with PANTHER:PTN000451188 chaperone-mediated protein transport ; GO:0072321 | inferred from biological aspect of ancestor with PANTHER:PTN000451188 mitochondrial intermembrane space protein transporter complex ; GO:0042719 | inferred from biological aspect of ancestor with PANTHER:PTN000451188 "CG42302, CG6857" IPR004217:Tim10/DDP family zinc finger CG42302 11-Aug-17 DroID_v2017_08 Drer\timm13 Scer\TIM13 Cele\tin-13 Xtro\timm13 Mmus\Timm13 Hsap\TIMM13 FBgn0027073 CG4302 - http://flybase.org/reports/FBgn0027073 FBgn0034604 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 UDP-glycosyltransferase activity ; GO:0008194 | inferred from sequence or structural similarity with UniProtKB:P18569 UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with UniProtKB:P18569 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:12531 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "GH09393, BEST:GH09393, CG4302" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG4302 11-Aug-17 DroID_v2017_08 "Drer\ugt1b7, Drer\ugt1ab, Drer\ugt5c3, Drer\ugt5e1, Drer\ugt5d1, Drer\ugt2b1, Drer\ugt5a4, Drer\ugt5g1, Drer\ugt2a5, Drer\ugt1b2, Drer\ugt2a6, Drer\ugt5b4, Drer\ugt8, Drer\ugt5b2, Drer\ugt1b4, Drer\ugt5c2, Drer\ugt5c1, Drer\ugt5a2, Drer\ugt5b3, Drer\ugt5g2, Drer\ugt2b6, Drer\ugt5a5, Drer\ugt1b3, Drer\ugt2a2, Drer\ugt2b3, Drer\ugt5a1, Drer\zgc:172315, Drer\ugt5b1, Drer\ugt5f1, Drer\ugt5b6, Drer\ugt1b5, Drer\ugt2b5" Scer\ATG26 "Cele\ugt-34, Cele\ugt-35, Cele\ugt-10, Cele\C55H1.1, Cele\F10D2.8, Cele\ugt-4, Cele\ugt-12, Cele\ugt-22, Cele\ugt-16, Cele\ugt-2, Cele\ugt-31, Cele\ugt-18, Cele\C03A7.13, Cele\ugt-51, Cele\ugt-49, Cele\ugt-54, Cele\ugt-9, Cele\ugt-36, Cele\ugt-52, Cele\ugt-7, Cele\ugt-48, Cele\ugt-57, Cele\ugt-32, Cele\ugt-38, Cele\ugt-8, Cele\ugt-20, Cele\ugt-50, Cele\ugt-24, Cele\ugt-21, Cele\ugt-65, Cele\F54C1.1, Cele\ugt-26, Cele\ugt-30, Cele\ugt-15, Cele\ugt-1, Cele\ugt-29, Cele\ugt-13, Cele\ugt-41, Cele\ugt-27, Cele\ugt-19, Cele\ugt-43, Cele\ugt-61, Cele\ugt-46, Cele\ugt-28, Cele\ugt-56, Cele\C03A7.12, Cele\ugt-17, Cele\ugt-37, Cele\ugt-40, Cele\ugt-25, Cele\ugt-62, Cele\ugt-44, Cele\ugt-59, Cele\C23G10.6, Cele\ugt-60, Cele\Y43D4A.2, Cele\ugt-33, Cele\ugt-47, Cele\ugt-39, Cele\ugt-53, Cele\ugt-45, Cele\ugt-55, Cele\ugt-3, Cele\ugt-58, Cele\ugt-14, Cele\H23N18.4, Cele\ugt-11, Cele\ugt-23, Cele\ugt-42, Cele\ugt-5, Cele\K04A8.10, Cele\ugt-6" "Xtro\ugt2a1, Xtro\ugt2b4, Xtro\ugt1a6, Xtro\ugt8, Xtro\ugt3a2" "Mmus\Ugt2b1, Mmus\Ugt2b35, Mmus\Ugt1a2, Mmus\Ugt1a1, Mmus\Ugt1a5, Mmus\Ugt2b38, Mmus\Ugt1a6a, Mmus\Ugt2b34, Mmus\Ugt2b5, Mmus\Ugt2b36, Mmus\Ugt2b37, Mmus\Ugt3a2, Mmus\Ugt8a, Mmus\Ugt1a10, Mmus\Ugt3a1, Mmus\Ugt1a9, Mmus\Ugt1a6b, Mmus\Ugt2a3, Mmus\Ugt1a7c, Mmus\Ugt2a2, Mmus\Ugt2a1" "Hsap\UGT1A1, Hsap\UGT1A4, Hsap\UGT2B28, Hsap\UGT2B7, Hsap\UGT3A1, Hsap\UGT1A3, Hsap\UGT2A3, Hsap\UGT3A2, Hsap\UGT2B11, Hsap\UGT1A9, Hsap\UGT2B10, Hsap\UGT1A7, Hsap\UGT2A1, Hsap\UGT1A6, Hsap\UGT2B15, Hsap\UGT1A5, Hsap\UGT2A2, Hsap\UGT2B17, Hsap\UGT2B4, Hsap\UGT8, Hsap\UGT1A8, Hsap\UGT1A10" viable FBgn0027382 Idefix\env Idefix element env http://flybase.org/reports/FBgn0027382 - transposable_element_gene - - - "ORF3, Idefix\env, env" "IPR012014:Retroelement-encoded protein, env-related" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259416 C606 - http://flybase.org/reports/FBgn0259416 gene - - - C606 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing margin,chaeta" FBgn0031718 CG14014 - http://flybase.org/reports/FBgn0031718 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from sequence or structural similarity regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype - CG14014 - CG14014 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0050477 CG30477 - http://flybase.org/reports/FBgn0050477 protein_coding_gene - - - CG30477 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264667 topiary topiary http://flybase.org/reports/FBgn0264667 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - topiary - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0085682 CG41551 - http://flybase.org/reports/FBgn0085682 protein_coding_gene - - - CG41551 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058373 CG40373 - http://flybase.org/reports/FBgn0058373 protein_coding_gene - - - CG40373 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259548 GG01153 - http://flybase.org/reports/FBgn0259548 gene - - - GG01153 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,metathoracic leg" FBgn0038828 CG17270 - http://flybase.org/reports/FBgn0038828 protein_coding_gene "protein binding, bridging ; GO:0030674 | inferred from biological aspect of ancestor with PANTHER:PTN000397028" ergosterol biosynthetic process ; GO:0006696 | inferred from biological aspect of ancestor with PANTHER:PTN000397028 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005352 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000397028 "anon-Liu, CG17270" IPR005352:Erg28 CG17270 11-Aug-17 DroID_v2017_08 Drer\gb:ev754742 Scer\ERG28 - Xtro\c14orf1 Mmus\0610007P14Rik Hsap\C14orf1 viable FBgn0260082 2L1687 - http://flybase.org/reports/FBgn0260082 gene - - - 2L1687 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0023523 Or2a Odorant receptor 2a http://flybase.org/reports/FBgn0023523 - protein_coding_gene "olfactory receptor activity ; GO:0004984 | inferred by curator from GO:0004888,GO:0007608 transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from direct assay" sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay sensory perception of smell ; GO:0007608 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence model dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "CG3206, 2a, EG:30B8.7, DOR62, AN4, 2F.1, Dor62, dor62, DOR2F.1, Or62, Or2F.1, Or2a, or2a" "IPR004117:Olfactory receptor, insect" CG3206 11-Aug-17 DroID_v2017_08 - - - - - - adult stage sensory neuron &&of antennal segment 3

"smell perception defective,viable" FBgn0084954 Rst(2b)Cyr Resistance 2b Cyromazine http://flybase.org/reports/FBgn0084954 gene - - - Rst(2b)Cyr - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant,partially" FBgn0037011 CG4858 - http://flybase.org/reports/FBgn0037011 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000808 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR028600" iron-sulfur cluster assembly ; GO:0016226 | inferred from electronic annotation with InterPro:IPR028600 - "CG4858, Nubp2" "IPR000808:Mrp, conserved site, IPR019591:Mrp/NBP35 ATP-binding protein, IPR033756:Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35, IPR028600:Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4858 11-Aug-17 DroID_v2017_08 "Drer\nubpl, Drer\nubp2, Drer\nubp1" "Scer\CFD1, Scer\NBP35" Cele\nubp-1 "Xtro\nubp2, Xtro\nubp1, Xtro\nubpl" "Mmus\Nubp1, Mmus\Nubpl, Mmus\Nubp2" "Hsap\NUBP2, Hsap\NUBP1, Hsap\NUBPL" "viable,locomotor rhythm defective" FBgn0004766 l(3)89Dc lethal (3) 89Dc http://flybase.org/reports/FBgn0004766 - gene - - - l(3)89Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035676 ssp6 short spindle 6 http://flybase.org/reports/FBgn0035676 protein_coding_gene - mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype - "ssp6, CG6619, Ssp6" IPR001478:PDZ domain CG6619 11-Aug-17 DroID_v2017_08 "Drer\grasp, Drer\lnx1, Drer\si:dkey-276j7.2, Drer\grip2b, Drer\slc9a3r1, Drer\grid2ipa, Drer\grip1, Drer\si:dkey-92i15.4, Drer\pard3bb, Drer\pdzd7b, Drer\inadl, Drer\il16, Drer\cytip, Drer\dlg5a" - Cele\gras-1 "Xtro\lnx1, Xtro\grid2ip, Xtro\dlg5, Xtro\grasp, Xtro\grip1, Xtro\grip2" "Mmus\Dlg5, Mmus\Grip2, Mmus\Ush1c, Mmus\Il16, Mmus\Mpdz, Mmus\Pdzd11, Mmus\Grip1, Mmus\Grid2ip, Mmus\Pdzd2, Mmus\Cytip, Mmus\Grasp, Mmus\Patj, Mmus\Pdzph1, Mmus\Lnx1" "Hsap\USH1C, Hsap\PDZD2, Hsap\MPDZ, Hsap\DLG5, Hsap\GRIP1, Hsap\PATJ, Hsap\CYTIP, Hsap\GRID2IP, Hsap\IL16, Hsap\PARD3B, Hsap\LNX1, Hsap\FRMPD2, Hsap\GRASP" "partially lethal - majority die,some die during pupal stage" DRSC10677 IEK -0.458912462 -3.509548101 -0.308570846 -4.480065682 -1.12833743 -1.73606069 FBgn0030268 Klp10A Kinesin-like protein at 10A http://flybase.org/reports/FBgn0030268 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from direct assay motor activity ; GO:0003774 | inferred from direct assay" mitotic chromosome movement towards spindle pole ; GO:0007079 | inferred from mutant phenotype spindle assembly involved in female meiosis I ; GO:0007057 | inferred from mutant phenotype establishment of meiotic spindle orientation ; GO:0051296 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype microtubule depolymerization ; GO:0007019 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype "mitotic spindle astral microtubule ; GO:0061673 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay mitotic spindle pole ; GO:0097431 | inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay cortical microtubule ; GO:0055028 | inferred from direct assay spindle pole ; GO:0000922 | inferred from direct assay meiotic spindle pole ; GO:0090619 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 meiotic spindle ; GO:0072687 | inferred from direct assay" "KLP10a, KLP10A, Kif2A, DmKLP10A, DmKlp10A, DmCG1453, CG1453, anon-WO03040301.142, Klp10A, klp10A, KIF 2A, KIF2A/B/C" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1453 11-Aug-17 DroID_v2017_08 "Drer\zgc:103670, Drer\kif2c" Scer\KIP3 Cele\klp-7 "Xtro\kif2a, Xtro\kif2c" "Mmus\Kif2c, Mmus\Kif2a, Mmus\Kif24, Mmus\Kif2b" "Hsap\KIF2A, Hsap\KIF2C, Hsap\KIF24, Hsap\KIF2B" "lethal,germline clone,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,mitotic cell cycle defective,visible" "meiotic spindlenos.UTR.THsimVP16,meiotic spindle | female | germline clone,meiotic spindle | femalenos.UTR.THsimVP16,meiotic spindle | femalemat.‘±Tub67C.THsimVP16,spindle microtubule,astral microtubule,mitosis & nuclear chromosome,spindle pole,S2 cell-line,spindle,microtubule,trichogen cell,wing disc,centriole" DRSC19601 K 0.565050112 -0.792925128 0.569719888 0.452311565 1.535140515 0.28134973 FBgn0037979 GCC185 GRIP and coiled-coil domain containing 185 kDa http://flybase.org/reports/FBgn0037979 protein_coding_gene "ADP-ribosylation factor binding ; GO:0030306 | inferred from physical interaction with Arl1 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2 protein homodimerization activity ; GO:0042803 | inferred from sequence model Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2, Rab30 identical protein binding ; GO:0042802 | inferred from sequence or structural similarity with HGNC:23218" "protein targeting to Golgi ; GO:0000042 | inferred from electronic annotation with InterPro:IPR000237 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with HGNC:23218 protein localization to Golgi apparatus ; GO:0034067 | inferred from sequence or structural similarity with HGNC:23218 Golgi vesicle transport ; GO:0048193 | inferred by curator from GO:0000138,GO:0017137" Golgi trans cisterna ; GO:0000138 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "dGCC185, GCC185, CG3532" IPR000237:GRIP domain CG3532 11-Aug-17 DroID_v2017_08 "Drer\golga3, Drer\LOC100332507, Drer\numa1" - "Cele\hcp-2, Cele\gcc-2, Cele\hcp-1" Xtro\gcc2 "Mmus\Gcc2, Mmus\Golga3, Mmus\Cep164, Mmus\Numa1" "Hsap\GOLGA3, Hsap\CEP164, Hsap\NUMA1, Hsap\GCC2" viable FBgn0019682 mor(1)1 mortality gene (1)1 http://flybase.org/reports/FBgn0019682 - gene - - - mor(1)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0084048 CR41184 - http://flybase.org/reports/FBgn0084048 non_protein_coding_gene - - - CR41184 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003098 PL(1)sp-S2 Polygenic locus sternopleural S2 http://flybase.org/reports/FBgn0003098 - gene - - - "PL(1)sp[S2], PL(1)sp-S2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030329 prtp pretaporter http://flybase.org/reports/FBgn0030329 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017937 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 positive regulation of apoptotic cell clearance ; GO:2000427 | inferred from mutant phenotype apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "p47, anon-EST:Posey253, CG1837, prtp" "IPR005788:Disulphide isomerase, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site" CG1837 11-Aug-17 DroID_v2017_08 "Drer\dnajc10, Drer\txndc16, Drer\txndc5, Drer\erp27, Drer\pdia6" "Scer\EPS1, Scer\MPD2, Scer\MPD1" - "Xtro\txndc5, Xtro\pdia6, Xtro\txndc16" "Mmus\Pdia5, Mmus\Pdia6, Mmus\Txndc16, Mmus\Txndc5, Mmus\Dnajc10, Mmus\Erp27" "Hsap\PDIA5, Hsap\ERP27, Hsap\PDIA6, Hsap\DNAJC10, Hsap\PDILT, Hsap\TXNDC5, Hsap\TXNDC16" viable "embryonic hemocyte,embryonic/larval glial cell" FBgn0283681 Tcs3 Tcs3 http://flybase.org/reports/FBgn0283681 protein_coding_gene - positive regulation of translational initiation ; GO:0045948 | inferred from mutant phenotype tRNA threonylcarbamoyladenosine modification ; GO:0002949 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype EKC/KEOPS complex ; GO:0000408 | inferred from electronic annotation with InterPro:IPR034680 cellular_component ; GO:0005575 | no biological data available "CG4933, kae1, Tcs3, tcs3, l(3)72Fb" "IPR000905:Gcp-like domain, IPR017860:Peptidase M22, conserved site, IPR017861:Kae1/TsaD family, IPR034680:tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP" CG4933 11-Aug-17 DroID_v2017_08 "Drer\osgep, Drer\osgepl1" "Scer\QRI7, Scer\KAE1" "Cele\C01G10.10, Cele\Y71H2AM.1" Xtro\osgep "Mmus\Osgep, Mmus\Osgepl1" "Hsap\OSGEPL1, Hsap\OSGEP" "lethal,recessive" FBgn0003358 Jon99Ci Jonah 99Ci http://flybase.org/reports/FBgn0003358 "FBgn0001288, FBgn0051039" protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 endopeptidase activity ; GO:0004175 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "143341_at, Ser99Dc, CG17951, 99Calpha, Jon99Cbeta, Jon99Calpha, Jon99Cbetai, Jon99Calphai, SP150, SER3, Jon99C1, Jon99C2, Jon99C, CG31039, Ser3, JonC, Jon99B, Jon99Ci, ser99Dc" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG31039 11-Aug-17 DroID_v2017_08 Drer\si:dkey-78l4.10 - Cele\svh-1 - "Mmus\C1s1, Mmus\Cela1, Mmus\C1s2" Hsap\PROC viable FBgn0039503 CG14262 - http://flybase.org/reports/FBgn0039503 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 CG14262 "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain" CG14262 11-Aug-17 DroID_v2017_08 Drer\klhl41b - Cele\hpo-9 Xtro\klhl41 - - viable FBgn0267185 CR45625 - http://flybase.org/reports/FBgn0267185 non_protein_coding_gene - - - CR45625 - CR45625 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038701 CG18493 - http://flybase.org/reports/FBgn0038701 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR008758 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008758 - CG18493 "IPR029058:Alpha/Beta hydrolase fold, IPR008758:Peptidase S28" CG18493 11-Aug-17 DroID_v2017_08 "Drer\prss16, Drer\prss16" - "Cele\pcp-2, Cele\pcp-4, Cele\F19C7.4, Cele\pcp-1, Cele\pcp-3, Cele\F28E10.5, Cele\F56F10.1, Cele\F19C7.2, Cele\K12H4.7, Cele\C26B9.5" "Xtro\LOC100145763, Xtro\prss16" Mmus\Prss16 Hsap\PRSS16 viable FBgn0001046 fs(3)HO133 female sterile (3) HO133 http://flybase.org/reports/FBgn0001046 - gene - - - "fs(3)133A, fs(3)HO133" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile oocyte FBgn0041758 eth-as312 eth-as312 http://flybase.org/reports/FBgn0041758 gene - - - "eth[as]312, eth-as312" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0069330 X-103-22 X-103-22 http://flybase.org/reports/FBgn0069330 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-103-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,germline clone,maternal effect,embryonic head" FBgn0040084 p76 p76 http://flybase.org/reports/FBgn0040084 gene - - - p76 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283476 Dhc16F Dynein heavy chain at 16F http://flybase.org/reports/FBgn0283476 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity inner dynein arm ; GO:0036156 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 "CG7092, Dhc16F, atoll, dhc, DHC, Dhc, cvl-6, DHC9" "IPR025662:Sigma-54 interaction domain, ATP-binding site 1, IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain" CG7092 11-Aug-17 DroID_v2017_08 "Drer\wu:fj30b09, Drer\dnah3, Drer\dnah2, Drer\dync1h1, Drer\dnah9l, Drer\dnah1, Drer\si:dkeyp-86b9.1, Drer\si:dkeyp-87a6.1, Drer\dnah12, Drer\dnah7, Drer\dnah7l" Scer\DYN1 "Cele\che-3, Cele\dhc-1" "Xtro\dnah6, Xtro\dnah2, Xtro\dnah7, Xtro\dnah14" "Mmus\Dnah17, Mmus\Dnah10, Mmus\Dnah14, Mmus\Dync1h1, Mmus\Dnah11, Mmus\Dnah6, Mmus\Dnhd1, Mmus\Dnah9, Mmus\Dnah5, Mmus\Dync2h1, Mmus\Dnah7b, Mmus\Dnah12, Mmus\Dnah8, Mmus\Dnah1, Mmus\Dnah2, Mmus\Dnah7a, Mmus\Dnah3, Mmus\Dnah7c" "Hsap\DNAH8, Hsap\DNAH1, Hsap\DYNC2H1, Hsap\DNAH10, Hsap\DNAH11, Hsap\DNHD1, Hsap\CCDC88B, Hsap\DNAH6, Hsap\DNAH17, Hsap\DNAH2, Hsap\DNAH5, Hsap\DYNC1H1, Hsap\DNAH9, Hsap\DNAH7, Hsap\DNAH3, Hsap\DNAH12, Hsap\DNAH14" FBgn0086533 snoRNA:Me18S-C419 - http://flybase.org/reports/FBgn0086533 snoRNA_gene - - - "snoRNA:Me18S-C419, Me18S-Cm419, Me18S-C419, snoRNA:RpL15-a" - CR43566 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261959 EU820 - http://flybase.org/reports/FBgn0261959 gene - - - EU820 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002866 mtb matt brown http://flybase.org/reports/FBgn0002866 - gene - - - mtb - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,visible,viable,male,poor,eye color defective" "wing,eye" FBgn0028372 isopeptidase-T-3 isopeptidase-T-3 http://flybase.org/reports/FBgn0028372 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "ISOT-3, CG11025, isopeptidase-T-3, IsoT-3, Isopeptidase-T-3" "IPR015940:Ubiquitin-associated domain, IPR009060:UBA-like" CG11025 11-Aug-17 DroID_v2017_08 Drer\ubac1 - - Xtro\ubac1 Mmus\Ubac1 Hsap\UBAC1 viable FBgn0028193 l(3)S022564 lethal (3) S022564 http://flybase.org/reports/FBgn0028193 gene - - - l(3)S022564 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264600 CR43949 - http://flybase.org/reports/FBgn0264600 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43949, CR43949" - CR43949 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259239 CG42337 - http://flybase.org/reports/FBgn0259239 protein_coding_gene - - - "CG42337, CG12976, CG12977, 42337" IPR015943:WD40/YVTN repeat-like-containing domain CG42337 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062601 Mod(var)1453 Mod(var)1453 http://flybase.org/reports/FBgn0062601 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1453, Mod(var)1453" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0002153 l(2)mbn lethal (2) malignant blood neoplasm http://flybase.org/reports/FBgn0002153 - gene - - - "mbn2, mbn-2, l(2)mbn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "plasmatocyte,podocyte,crystal cell,embryonic/larval lymph gland" FBgn0029667 Gas8 Growth arrest specific protein 8 http://flybase.org/reports/FBgn0029667 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000774884 flagellated sperm motility ; GO:0030317 | inferred from sequence or structural similarity with UniProtKB:Q60779 cellular protein localization ; GO:0034613 | inferred from biological aspect of ancestor with PANTHER:PTN000774884 motile cilium ; GO:0031514 | inferred from electronic annotation with InterPro:IPR025593 microtubule ; GO:0005874 | inferred from biological aspect of ancestor with PANTHER:PTN000774884 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000774884 cytoplasm ; GO:0005737 | non-traceable author statement "CG14271, Gas8" IPR025593:Growth arrest-specific protein 8 CG14271 11-Aug-17 DroID_v2017_08 "Drer\gas8, Drer\pank1b, Drer\pank1a, Drer\pank2" - "Cele\C17H1.13, Cele\C17H1.8, Cele\gasr-8" "Xtro\pank3, Xtro\gas8, Xtro\pank2" "Mmus\Pank1, Mmus\Gas8, Mmus\Pank2, Mmus\Pank3" "Hsap\PANK3, Hsap\GAS8, Hsap\PANK2" viable FBgn0259672 B0674 - http://flybase.org/reports/FBgn0259672 gene - - - B0674 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,proboscis,arista" FBgn0030117 ric8b ric8b http://flybase.org/reports/FBgn0030117 pseudogene_attribute - - - "CG15910, CR15910, ric8b, ric-8b" - CR15910 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025373 Fpps Farnesyl pyrophosphate synthase http://flybase.org/reports/FBgn0025373 "FBgn0022145, FBgn0042628" protein_coding_gene geranyltranstransferase activity ; GO:0004337 | inferred from sequence or structural similarity geranyltranstransferase activity ; GO:0004337 | inferred from biological aspect of ancestor with PANTHER:PTN000162949 dimethylallyltranstransferase activity ; GO:0004161 | inferred from biological aspect of ancestor with PANTHER:PTN000162949 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx farnesyl diphosphate biosynthetic process ; GO:0045337 | inferred from biological aspect of ancestor with PANTHER:PTN000162949 germ cell migration ; GO:0008354 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000162949 "fpps, CG12389, l(2)k06103, FPS, v(2)k03514, fps, Fpps, DmFPPSase, DmFPPS, DmFPS, FPPS" "IPR000092:Polyprenyl synthetase, IPR008949:Isoprenoid synthase domain, IPR033749:Polyprenyl synthetase, conserved site" CG12389 11-Aug-17 DroID_v2017_08 "Drer\rusc1, Drer\fdps" Scer\ERG20 Cele\fdps-1 Xtro\fdps "Mmus\Fdps, Mmus\Rusc1" "Hsap\RUSC1, Hsap\FDPS" "viable,lethal,recessive,visible" "crystal cell,pole cell,germline clone,rescuable maternal effect,pole cell & embryonic nervous system" FBgn0017367 l(3)89Bo lethal (3) 89Bo http://flybase.org/reports/FBgn0017367 - gene - - - "l(3)89Bm, l(3)89Bo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority live" FBgn0265040 CR44157 - http://flybase.org/reports/FBgn0265040 non_protein_coding_gene - - - CR44157 - CR44157 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025838 CG2652 - http://flybase.org/reports/FBgn0025838 - protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR005033" - "EG:155E2.5, CG2652" IPR005033:YEATS CG2652 11-Aug-17 DroID_v2017_08 "Drer\mllt1a, Drer\mllt1b, Drer\yeats4, Drer\yeats2, Drer\mllt3" "Scer\TAF14, Scer\SAS5, Scer\YAF9" "Cele\gfl-1, Cele\Y105E8B.7" "Xtro\mllt1, Xtro\mllt3, Xtro\yeats2, Xtro\yeats4" "Mmus\Yeats2, Mmus\Yeats4, Mmus\Mllt1, Mmus\Mllt3" "Hsap\MLLT3, Hsap\MLLT1, Hsap\YEATS4, Hsap\YEATS2" "viable,fertile" FBgn0083116 W12 W12 http://flybase.org/reports/FBgn0083116 gene - - - W12 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable wing FBgn0032850 Kua Kua http://flybase.org/reports/FBgn0032850 protein_coding_gene fatty acid alpha-hydroxylase activity ; GO:0080132 | inferred from sequence or structural similarity with SGD:S000004885 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 integral component of membrane ; GO:0016021 | inferred from sequence model "38B.18, CG10723, Kua" "IPR019547:B domain of TMEM189, localisation domain" CG10723 11-Aug-17 DroID_v2017_08 "Drer\ube2v2, Drer\tmem189, Drer\ube2v1, Drer\si:ch211-212o1.2" - Cele\Y53C10A.5 "Xtro\ube2v1, Xtro\ube2v2, Xtro\tmem189" "Mmus\Ube2v2, Mmus\Ube2v1, Mmus\Tmem189" "Hsap\TMEM189, Hsap\TMEM189-UBE2V1, Hsap\UBE2V1, Hsap\UBE2V2" viable FBgn0010663 l(2)10491 lethal (2) 10491 http://flybase.net/reports/FBgn0010663.html gene 11-Aug-17 DroID_v2017_08 "partially lethal - majority die,lethal,recessive" FBgn0262687 CR43157 - http://flybase.org/reports/FBgn0262687 non_protein_coding_gene - - - CR43157 - CR43157 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085619 CG41329 - http://flybase.org/reports/FBgn0085619 protein_coding_gene - - - CG41329 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250785 vari varicose http://flybase.org/reports/FBgn0250785 protein_coding_gene - "open tracheal system development ; GO:0007424 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype dorsal trunk growth, open tracheal system ; GO:0035001 | inferred from mutant phenotype" septate junction ; GO:0005918 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay "vari, CG9326, l(2)03953b, l(2)03953, 38E.21, szar, l(2)38EFa, Vari" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014775:L27 domain, C-terminal, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR008144:Guanylate kinase-like domain, IPR004172:L27 domain, IPR001478:PDZ domain, IPR001452:SH3 domain, IPR020590:Guanylate kinase, conserved site, IPR011511:Variant SH3 domain" CG9326 11-Aug-17 DroID_v2017_08 "Drer\mpp5a, Drer\LOC556594, Drer\si:ch73-272h16.4, Drer\mpp2a, Drer\mpp7b, Drer\caska, Drer\mpp3b, Drer\mpp5b, Drer\mpp6b, Drer\mpp2b, Drer\mpp1, Drer\mpp7a, Drer\mpp3a, Drer\mpp6a, Drer\mpp4a" Scer\GUK1 "Cele\magu-3, Cele\magu-1, Cele\magu-2, Cele\lin-2" "Xtro\mpp1, Xtro\mpp5, Xtro\cask, Xtro\mpp7, Xtro\mpp6, Xtro\mpp2" "Mmus\Mpp3, Mmus\Mpp6, Mmus\Mpp7, Mmus\Mpp1, Mmus\Mpp2, Mmus\Mpp4, Mmus\Cask, Mmus\Mpp5" "Hsap\MPP5, Hsap\MPP4, Hsap\MPP3, Hsap\MPP7, Hsap\MPP6, Hsap\MPP2, Hsap\MPP1, Hsap\CASK" FBgn0052461 CG32461 - http://flybase.org/reports/FBgn0052461 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32461 - CG32461 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016932 smi51A smell impaired 51A http://flybase.org/reports/FBgn0016932 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi51A - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0259985 Mppe Metallophosphoesterase http://flybase.org/reports/FBgn0259985 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from direct assay inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000330056 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000330056 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000330056 Golgi apparatus ; GO:0005794 | inferred from direct assay "CG8889, Mppe, GS11471, 11471, dmppe, dMPPE" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR029052:Metallo-dependent phosphatase-like, IPR033308:PGAP5/Cdc1/Ted1" CG8889 11-Aug-17 DroID_v2017_08 Drer\mppe1 "Scer\TED1, Scer\CDC1" "Cele\B0511.13, Cele\ZK792.7" Xtro\mppe1 Mmus\Mppe1 "Hsap\MPPE1, Hsap\CPPED1" FBgn0004988 Branchlet Branchlet http://flybase.org/reports/FBgn0004988 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Branchlet, Bt" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "wing,posterior crossvein,adult abdominal segment" FBgn0031388 CG12674 - http://flybase.org/reports/FBgn0031388 protein_coding_gene molecular_function ; GO:0003674 | no biological data available histone modification ; GO:0016570 | inferred from electronic annotation with InterPro:IPR007133 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from electronic annotation with InterPro:IPR007133 biological_process ; GO:0008150 | no biological data available Cdc73/Paf1 complex ; GO:0016593 | inferred from electronic annotation with InterPro:IPR007133 cellular_component ; GO:0005575 | no biological data available CG12674 IPR007133:RNA polymerase II associated factor Paf1 CG12674 11-Aug-17 DroID_v2017_08 Drer\paf1 Scer\PAF1 "Cele\tag-343, Cele\pafo-1" Xtro\paf1 Mmus\Paf1 Hsap\PAF1 viable FBgn0015004 ACE3 Amplification-control-element-on-3 http://flybase.org/reports/FBgn0015004 - region - - - "ACE-3, ACE3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266088 CR44830 - http://flybase.org/reports/FBgn0266088 non_protein_coding_gene - - - CR44830 - CR44830 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031337 CG14346 - http://flybase.org/reports/FBgn0031337 protein_coding_gene - - - CG14346 - CG14346 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0044047 Ilp6 Insulin-like peptide 6 http://flybase.org/reports/FBgn0044047 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "DILP, dilp, dilp-6, Dilp, dilp6, Dilp 6, CG14049, Ilp6, Ilp, dIlp6, Dilp6, dILP6, DILP6, Ilp-6, ilp6, DILP-6" IPR016179:Insulin-like CG14049 11-Aug-17 DroID_v2017_08 - - - - - - larval stage | third instar embryonic/larval midgut

"stress response defective,small body,large body,heat sensitive,chemical resistant,viable,fertile,decreased cell number,partially lethal - majority die,some die during pupal stage" embryonic/larval neuroblast FBgn0259588 GG01544 - http://flybase.org/reports/FBgn0259588 gene - - - GG01544 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0011307 l(3)j1A1 lethal (3) j1A1 http://flybase.org/reports/FBgn0011307 - gene - - - l(3)j1A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062565 Or19b Odorant receptor 19b http://flybase.org/reports/FBgn0062565 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 olfactory receptor activity ; GO:0004984 | inferred from sequence or structural similarity with Or19a odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from sequence or structural similarity with Or19a detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from sequence model "CG32825, Or19b" "IPR004117:Olfactory receptor, insect" CG32825 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264346 CR43802 - http://flybase.org/reports/FBgn0264346 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "CR43802, lincRNA.166" - CR43802 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052161 CG32161 - http://flybase.org/reports/FBgn0052161 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32161 IPR031754:Protein of unknown function DUF4736 CG32161 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052797 CG32797 - http://flybase.org/reports/FBgn0052797 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001034975 CG32797 IPR026780:Proline-rich nuclear receptor coactivator 1/2 CG32797 11-Aug-17 DroID_v2017_08 "Drer\pnrc1, Drer\pnrc2" - - - "Mmus\Pnrc1, Mmus\Pnrc2" "Hsap\PNRC2, Hsap\PNRC1" FBgn0024360 MTPAP mitochondrial poly(A) polymerase http://flybase.org/reports/FBgn0024360 FBgn0024981 protein_coding_gene RNA adenylyltransferase activity ; GO:1990817 | inferred from mutant phenotype RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:25532 mitochondrial mRNA polyadenylation ; GO:0097222 | inferred from mutant phenotype tRNA stabilization ; GO:0036416 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from sequence or structural similarity with HGNC:25532 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:25532 mitochondrion ; GO:0005739 | inferred from direct assay "EG:8D8.8, DmNP_569904, CG11418, MTPAP, DmMTPAP" IPR002058:PAP/25A-associated CG11418 11-Aug-17 DroID_v2017_08 "Drer\tut1, Drer\mtpap, Drer\zcchc11, Drer\zcchc6, Drer\papd4" - "Cele\mut-2, Cele\usip-1, Cele\pup-3" "Xtro\zcchc11, Xtro\mtpap, Xtro\zcchc6, Xtro\tut1, Xtro\papd4" "Mmus\Zcchc11, Mmus\Zcchc6, Mmus\Tut1, Mmus\Mtpap, Mmus\Papd4" "Hsap\ZCCHC11, Hsap\MTPAP, Hsap\PAPD4, Hsap\TUT1, Hsap\ZCCHC6" "lethal,some die during pupal stage,some die during larval stage,viable,visible" trichogen cell FBgn0037395 CG10280 - http://flybase.org/reports/FBgn0037395 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026" - CG10280 "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG10280 11-Aug-17 DroID_v2017_08 "Drer\he2, Drer\c6ast4, Drer\si:ch73-40a17.3, Drer\bmp1a, Drer\LOC100003133, Drer\he1b, Drer\mep1a.2, Drer\c6ast3, Drer\c6ast1, Drer\tnfaip6, Drer\bmp1b, Drer\si:ch211-167j6.5, Drer\tll1, Drer\he1a, Drer\LOC797085, Drer\mep1b, Drer\npsn, Drer\mep1a.1" - "Cele\nas-7, Cele\nas-8, Cele\nas-14, Cele\nas-12, Cele\nas-13, Cele\dpy-31, Cele\Y19D10A.6, Cele\ZC116.3, Cele\nas-1, Cele\nas-15, Cele\nas-39, Cele\nas-6, Cele\nas-4, Cele\hch-1, Cele\nas-2, Cele\nas-5, Cele\nas-3" "Xtro\bmp1, Xtro\LOC100498584, Xtro\LOC100492324, Xtro\tll1, Xtro\LOC100489456, Xtro\tll2, Xtro\accs, Xtro\mep1b, Xtro\cubn, Xtro\uvs.2, Xtro\mep1a, Xtro\tnfaip6" "Mmus\Cubn, Mmus\Mep1b, Mmus\Astl, Mmus\Bmp1, Mmus\Adgrg6, Mmus\Tnfaip6, Mmus\Dcbld2, Mmus\Tll1, Mmus\Tll2, Mmus\Mep1a" "Hsap\TLL2, Hsap\CUBN, Hsap\BMP1, Hsap\DCBLD2, Hsap\TNFAIP6, Hsap\MEP1B, Hsap\ASTL, Hsap\TLL1, Hsap\ADGRG6, Hsap\MEP1A" viable FBgn0051265 CG31265 - http://flybase.org/reports/FBgn0051265 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP126, CG5233, CG31265" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG31265 11-Aug-17 DroID_v2017_08 - - Cele\nhl-3 - Mmus\Prss37 Hsap\PRSS37 viable FBgn0028641 fs(2)k09833 fs(2)k09833 http://flybase.net/reports/FBgn0028641.html gene 11-Aug-17 DroID_v2017_08 "female sterile,recessive" FBgn0029145 P(3)78A P(3)78A http://flybase.org/reports/FBgn0029145 gene - - - P(3)78A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005082 fs(2)OW806 female sterile (2) OW806 http://flybase.org/reports/FBgn0005082 - gene - - - fs(2)OW806 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032864 CG2493 - http://flybase.org/reports/FBgn0032864 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR008758 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008758 - "38C.55, CG2493" "IPR008758:Peptidase S28, IPR029058:Alpha/Beta hydrolase fold" CG2493 11-Aug-17 DroID_v2017_08 "Drer\prcp, Drer\dpp7" - "Cele\pcp-1, Cele\pcp-5, Cele\F19C7.4, Cele\F19C7.2" "Xtro\smyd2, Xtro\prcp" "Mmus\Dpp7, Mmus\Prcp" "Hsap\PRCP, Hsap\DPP7" "viable,fertile" FBgn0005417 l(1)adl6 lethal (1) adl6 http://flybase.org/reports/FBgn0005417 - gene - - - "l(1)adl-6, l(1)adl6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,short lived,heat sensitive,partially lethal - majority die,lethal" eye FBgn0015474 l(2)45Ab lethal (2) 45Ab http://flybase.org/reports/FBgn0015474 - gene - - - l(2)45Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0267556 CR45896 - http://flybase.org/reports/FBgn0267556 non_protein_coding_gene - - - CR45896 - CR45896 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032479 CG16974 - http://flybase.org/reports/FBgn0032479 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - "CT35580, CG16974, Dromel_CG16974_FBtr0080489_mORF" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR032675:Leucine-rich repeat domain, L domain-like" CG16974 11-Aug-17 DroID_v2017_08 "Drer\igfals, Drer\lrrc15, Drer\vasnb, Drer\vasna" - Cele\iglr-2 "Xtro\igfals, Xtro\lingo4, Xtro\vasn" "Mmus\Vasn, Mmus\Igfals" "Hsap\IGFALS, Hsap\VASN" viable FBgn0023466 anon-56Cb anon-56Cb http://flybase.org/reports/FBgn0023466 - gene - - - anon-56Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage && oogenesis stage ovary

FBgn0014190 hni he's not interested http://flybase.org/reports/FBgn0014190 - gene - courtship behavior ; GO:0007619 | non-traceable author statement mating behavior ; GO:0007617 | traceable author statement - hni - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004062 blt ballet http://flybase.org/reports/FBgn0004062 - gene - - - blt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,poor,partially lethal - majority die,female" "wing,wing vein" FBgn0000643 fcl foreclosed http://flybase.org/reports/FBgn0000643 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fcl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" "chorion | germline clone,dorsal appendage,germline clone,ovary,cuticle,dorsal,embryonic epidermis,embryonic Malpighian tubule" FBgn0031777 CG9154 - http://flybase.org/reports/FBgn0031777 protein_coding_gene "methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR002052, InterPro:IPR019369 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002052" methylation ; GO:0032259 | inferred from electronic annotation with InterPro:IPR002052 cellular_component ; GO:0005575 | no biological data available CG9154 "IPR002052:DNA methylase, N-6 adenine-specific, conserved site, IPR019369:Protein-lysine N-methyltransferase Efm5" CG9154 11-Aug-17 DroID_v2017_08 Drer\n6amt2 Scer\EFM5 "Cele\M142.8, Cele\F33A8.4" Xtro\n6amt2 Mmus\Eef1akmt1 Hsap\EEF1AKMT1 "viable,visible" trichogen cell FBgn0083071 ogre::shakB ogre::shakB http://flybase.org/reports/FBgn0083071 engineered_fusion_gene - - - ogre::shakB - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023225 E(gammaTub37C[1]) Enhancer of gamma-Tubulin at 37C http://flybase.org/reports/FBgn0023225 - gene - - - E(gammaTub37C[1]) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031808 CG9507 - http://flybase.org/reports/FBgn0031808 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "neuropeptide signaling pathway ; GO:0007218 | inferred from electronic annotation with InterPro:IPR029736 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG9507 "IPR000718:Peptidase M13, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR029736:Endothelin-converting enzyme-like 1, IPR008753:Peptidase M13, N-terminal domain" CG9507 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\mmel1, Drer\phex, Drer\ece2b" - "Cele\nep-3, Cele\nep-8, Cele\nep-24, Cele\nep-23, Cele\nep-10, Cele\nep-18, Cele\nep-6, Cele\nep-26, Cele\nep-16, Cele\nep-19, Cele\nep-20, Cele\nep-12, Cele\nep-7, Cele\nep-13, Cele\nep-17, Cele\nep-9, Cele\nep-21, Cele\nep-5" "Xtro\ece1, Xtro\ecel1, Xtro\ece2, Xtro\mmel1" "Mmus\Phex, Mmus\Ece2, Mmus\Ecel1, Mmus\Mmel1, Mmus\Mme, Mmus\Ece1, Mmus\Kel" "Hsap\KEL, Hsap\ECE1, Hsap\ECE2, Hsap\MMEL1, Hsap\MME, Hsap\PHEX, Hsap\ECEL1" viable FBgn0064167 l(3)85.43 lethal (3) 85.43 http://flybase.org/reports/FBgn0064167 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "85.43, l(3)85.43" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal oocyte FBgn0266083 ocm over compensating males http://flybase.org/reports/FBgn0266083 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001699" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001699 neurogenesis ; GO:0022008 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype dosage compensation ; GO:0007549 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "CG3363, ocm, Mod(GMroX1)A, Mga" "IPR001699:Transcription factor, T-box, IPR032060:Domain of unknown function DUF4801" CG3363 11-Aug-17 DroID_v2017_08 Drer\tbx1 - "Cele\tbx-35, Cele\tbx-34, Cele\tbx-31, Cele\tbx-32, Cele\tbx-41, Cele\mls-1, Cele\ZK328.6, Cele\tbx-38, Cele\tbx-37" - "Mmus\Tbx10, Mmus\Tbx1" "Hsap\TBX10, Hsap\TBX1" DRSC26248 K -0.920089155 0.356804627 -1.031362257 0.212837923 0.38869791 2.474522399 FBgn0039186 CG5746 - http://flybase.org/reports/FBgn0039186 protein_coding_gene - - - CG5746 - CG5746 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069247 bop brontops http://flybase.org/reports/FBgn0069247 gene molecular_function ; GO:0003674 | no biological data available oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bop - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "egg,germline clone,maternal effect,dorsal appendage" FBgn0267530 CR45870 - http://flybase.org/reports/FBgn0267530 non_protein_coding_gene - - - CR45870 - CR45870 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004234 l(3)93Bh lethal (3) 93Bh http://flybase.org/reports/FBgn0004234 - gene - - - "rlr6, l(3)93Bh" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035540 Syx17 Syntaxin 17 http://flybase.org/reports/FBgn0035540 protein_coding_gene "protein complex binding ; GO:0032403 | inferred from physical interaction with car, dor SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNAP receptor activity ; GO:0005484 | inferred from physical interaction with Snap29, Vamp7 SNARE binding ; GO:0000149 | inferred from physical interaction with Snap29, Vamp7" regulation of autophagy ; GO:0010506 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity vesicle docking ; GO:0048278 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNARE complex ; GO:0031201 | inferred from direct assay autophagosome ; GO:0005776 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 autophagosome membrane ; GO:0000421 | inferred from direct assay "DmSyx17, Dm Syx17, CG7452, Syx17, Syx, S17" "IPR000727:Target SNARE coiled-coil homology domain, IPR010989:SNARE" CG7452 11-Aug-17 DroID_v2017_08 "Drer\stx17, Drer\stx12, Drer\stx7l, Drer\stx12l" "Scer\PEP12, Scer\VAM3" "Cele\syx-2, Cele\syx-17, Cele\syx-3, Cele\syx-7, Cele\syx-4" "Xtro\stx7, Xtro\tsnare1, Xtro\stx12" "Mmus\Stx12, Mmus\Stx17, Mmus\Stx7" "Hsap\STX12, Hsap\STX7, Hsap\TSNARE1, Hsap\STX17" "gravitaxis defective,nutrition conditional,locomotor behavior defective,increased cell death,viable,fertile" "embryonic/larval fat body,nutrition conditional,autolysosome | wandering third instar larval stage | nutrition conditionalExel8098),autophagic vacuole | supernumerary | nutrition conditionalExel8098),fat body,adult brain" FBgn0028261 l(3)64Ao lethal (3) 64Ao http://flybase.org/reports/FBgn0028261 gene - - - l(3)64Ao - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265800 CR44589 - http://flybase.org/reports/FBgn0265800 non_protein_coding_gene - - - CR44589 - CR44589 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069962 CG41050 - http://flybase.org/reports/FBgn0069962 protein_coding_gene - - - CG41050 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004765 l(3)89Db lethal (3) 89Db http://flybase.org/reports/FBgn0004765 - gene - - - l(3)89Db - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013697 mt:tRNA:Lys-CTT mitochondrial transfer RNA:Lysine-CTT http://flybase.org/reports/FBgn0013697 FBgn0002867 tRNA_gene - - - "CR34070, tRNA[Lys], mt-tRNA[Lys] (CUU), mtdbD00006299, mt:tRNA:Lys-CTT, mt:tRNA:K" - CR34070 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021939 l(2)k10815 lethal (2) k10815 http://flybase.net/reports/FBgn0021939.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0027192 l(2)56CDa lethal (2) 56CDa http://flybase.org/reports/FBgn0027192 - gene - - - l(2)56CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021915 l(2)k11404 lethal (2) k11404 http://flybase.net/reports/FBgn0021915.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0085602 CG41293 - http://flybase.org/reports/FBgn0085602 protein_coding_gene - - - CG41293 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001357 l(1)1EFf lethal (1) 1EFf http://flybase.org/reports/FBgn0001357 - gene - - - "l(1)BA6, l(1)1EFf" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051167 tRNA:Ser-GCT-1-1 transfer RNA:Serine-GCT 1-1 http://flybase.org/reports/FBgn0051167 tRNA_gene AGC codon-amino acid adaptor activity ; GO:0033446 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033446 cytosol ; GO:0005829 | inferred by curator from GO:0033446 "tRNA[Ser][[2b]], AE002708.trna38-SerGCT, tRNA:S:GCT:AE002708-c, tRNA:ser, tRNA:S, tRNA:ser2b:94A, tRNA:ser2b, tRNA:S2b, tRNA:S2b:94A, CR31167, tRNA[[Ser]], chr3R.trna44-SerGCT, tRNA-Ser-GCT-1-1, tRNA:Ser-GCT-1-1, tRNA:CR31167, AGC" - CR31167 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035567 CG7514 - http://flybase.org/reports/FBgn0035567 protein_coding_gene oxoglutarate:malate antiporter activity ; GO:0015367 | inferred from sequence or structural similarity with UniProtKB:Q02978 oxoglutarate:malate antiporter activity ; GO:0015367 | inferred from biological aspect of ancestor with PANTHER:PTN001942042 alpha-ketoglutarate transport ; GO:0015742 | inferred from sequence or structural similarity with UniProtKB:Q02978 malate transport ; GO:0015743 | inferred from sequence or structural similarity with UniProtKB:Q02978 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:Q02978 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001942042 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q02978 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 CG7514 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG7514 11-Aug-17 DroID_v2017_08 "Drer\slc25a11, Drer\slc25a14, Drer\si:ch1073-100f3.2, Drer\mrpl12, Drer\slc25a10, Drer\ucp2" Scer\DIC1 "Cele\slc-25A10, Cele\ucp-4, Cele\misc-1, Cele\mrpl-12" "Xtro\rangrf, Xtro\slc25a10, Xtro\ucp2, Xtro\ucp1, Xtro\slc25a30, Xtro\slc25a27" "Mmus\Slc25a11, Mmus\Slc25a30, Mmus\Slc25a14, Mmus\Slc25a27, Mmus\Ucp1, Mmus\Mrpl12, Mmus\Ucp3, Mmus\Slc25a10, Mmus\Ucp2" "Hsap\SLC25A10, Hsap\MRPL12, Hsap\SLC25A27, Hsap\SLC25A11, Hsap\UCP1, Hsap\SLC25A30, Hsap\SLC25A14, Hsap\UCP3, Hsap\UCP2" "viable,fertile" DRSC08597 K 0.683349386 0.23126407 0.546586326 -0.04709146 -0.513419799 1.560527119 FBgn0053412 5SrRNA:CR33412 5SrRNA:CR33412 http://flybase.org/reports/FBgn0053412 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33412, 5SrRNA:CR33412" - CR33412 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260479 CG31904 - http://flybase.org/reports/FBgn0260479 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000175 "anon-WO0149848.5, CG31904, CG31904-PD" "IPR000175:Sodium:neurotransmitter symporter, IPR031874:Adult cuticle protein 1" CG31904 11-Aug-17 DroID_v2017_08 "Drer\slc6a11a, Drer\si:ch211-132b12.3, Drer\zgc:174946, Drer\si:ch211-132b12.2, Drer\slc6a13, Drer\slc6a13l, Drer\si:ch211-132b12.1, Drer\si:ch211-132b12.6" - "Cele\mod-5, Cele\snf-6" Xtro\slc6a13 - - FBgn0263395 hppy happyhour http://flybase.org/reports/FBgn0263395 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR021160 MAP kinase kinase kinase kinase activity ; GO:0008349 | inferred from electronic annotation with InterPro:IPR021160 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from genetic interaction with Tsc1" behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | inferred from mutant phenotype regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from genetic interaction with gig inferred from genetic interaction with Akt1 inferred from genetic interaction with Pten positive regulation of hippo signaling ; GO:0035332 | inferred from genetic interaction with wts protein phosphorylation ; GO:0006468 | inferred from genetic interaction with Tsc1 positive regulation of TOR signaling ; GO:0032008 | inferred from genetic interaction with Tsc1 protein phosphorylation ; GO:0006468 | non-traceable author statement negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with aop inferred from genetic interaction with Egfr positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype regulation of growth rate ; GO:0040009 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from direct assay regulation of TOR signaling ; GO:0032006 | inferred from genetic interaction with Tor inferred from genetic interaction with RagC-D inferred from genetic interaction with path inferred from genetic interaction with slif inferred from genetic interaction with RagA-B inferred from genetic interaction with Rheb inferred from genetic interaction with S6k triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from direct assay positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype TORC1 complex ; GO:0031931 | inferred from physical interaction with Tor inferred from physical interaction with RagC-D inferred from physical interaction with RagA-B cytoplasm ; GO:0005737 | inferred from direct assay "CG7097, hppy, l(2)SH1261, l(2)SH2 1261, EP-704, MAP4K3, anon-WO0153538.68, GLK/KHS1, CG7097/hppy, Hppy" "IPR021160:Mitogen-activated protein (MAP) kinase kinase kinase kinase, IPR017441:Protein kinase, ATP binding site, IPR011009:Protein kinase-like domain, IPR001180:Citron homology (CNH) domain, IPR000719:Protein kinase domain" CG7097 11-Aug-17 DroID_v2017_08 "Drer\LOC101883459, Drer\map4k3a, Drer\map4k2, Drer\map4k3b, Drer\map4k6, Drer\map4k5" Scer\KIC1 "Cele\nsy-1, Cele\mtk-1, Cele\gck-2" "Xtro\map4k5, Xtro\map4k3" "Mmus\Map4k1, Mmus\Map4k5, Mmus\Map4k2, Mmus\Map4k3" "Hsap\MAP4K3, Hsap\MAP4K1, Hsap\MAP4K5, Hsap\MAP4K2" FBgn0015447 l(1)8Ae lethal (1) 8Ae http://flybase.org/reports/FBgn0015447 - gene - - - l(1)8Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085657 CG41496 - http://flybase.org/reports/FBgn0085657 protein_coding_gene - - - CG41496 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025682 scf supercoiling factor http://flybase.org/reports/FBgn0025682 FBgn0025546 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 DNA topoisomerase activity ; GO:0003916 | contributes_to inferred from direct assay "dosage compensation by hyperactivation of X chromosome ; GO:0009047 | inferred from mutant phenotype DNA topological change ; GO:0006265 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "SCF, DCB-45, CK02682, anon-EST:Posey14, CG9148, BEST:CK02682, scf" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG9148 11-Aug-17 DroID_v2017_08 "Drer\rcn1, Drer\rcn2, Drer\rcn3, Drer\calub, Drer\calua" - "Cele\calu-1, Cele\calu-2" "Xtro\calu, Xtro\rcn2, Xtro\rcn1, Xtro\rcn3" "Mmus\Rcn2, Mmus\Rcn3, Mmus\Rcn1, Mmus\Calu" "Hsap\RCN1, Hsap\RCN3, Hsap\RCN2, Hsap\CALU" embryonic stage -- adult stage " oogenesis stage && adult stage | female , embryonic stage | late , larval stage , embryonic stage | blastoderm " " oocyte

, macrophage

, embryonic/larval fat body

, trachea

, embryonic/larval salivary gland | anterior

, pericardial cell

, embryonic/larval salivary gland | posterior

, embryonic/larval hindgut

, garland cell

" "lethal,male,visible,dominant,homeotic,partially,viable,female,lethal - all die before end of larval stage,recessive,some die during third instar larval stage" "adult abdominal segment 6,male,adult abdominal segment 5,ectopic,polytene chromosome | male" FBgn0267581 CR45921 - http://flybase.org/reports/FBgn0267581 non_protein_coding_gene - - - CR45921 - CR45921 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037920 CG14710 - http://flybase.org/reports/FBgn0037920 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG14710 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG14710 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-113d7.10, Drer\snai1b, Drer\snai3, Drer\snai1a" Scer\AZF1 - - "Mmus\Zfp369, Mmus\Zfp110, Mmus\Zfp445, Mmus\Zscan5b, Mmus\Zfp24, Mmus\Snai1" "Hsap\ZNF784, Hsap\SNAI1" "viable,fertile" FBgn0004099 l(2)60Dg lethal (2) 60Dg http://flybase.org/reports/FBgn0004099 - gene - - - l(2)60Dg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0016629 E(gl)2E Enhancer of glass 2E http://flybase.org/reports/FBgn0016629 - gene - - - E(gl)2E - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259673 B0975 - http://flybase.org/reports/FBgn0259673 gene - - - B0975 - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,chaeta,ectopic,wing vein L3" FBgn0065174 l(3)SH017 lethal (3) SH017 http://flybase.org/reports/FBgn0065174 gene - - - "l(3)SH017, l(2)SH3 017" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033443 CG1698 - http://flybase.org/reports/FBgn0033443 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 amino acid transmembrane import ; GO:0044745 | inferred from sequence model transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 "CG1698, DmNAT5" IPR000175:Sodium:neurotransmitter symporter CG1698 11-Aug-17 DroID_v2017_08 "Drer\zgc:158225, Drer\slc6a11a, Drer\slc6a19b, Drer\slc6a19a.1, Drer\slc6a16a, Drer\slc6a16b, Drer\slc6a14, Drer\si:ch211-132b12.3, Drer\slc6a13, Drer\slc6a18, Drer\slc6a1a, Drer\si:ch211-132b12.6, Drer\slc6a1l, Drer\slc6a4b, Drer\slc6a1b, Drer\si:ch211-117c9.5, Drer\slc6a9, Drer\slc6a2, Drer\slc6a6a, Drer\slc6a17, Drer\slc6a15, Drer\slc6a13, Drer\si:ch211-132b12.2, Drer\zgc:174946, Drer\slc6a8, Drer\slc6a13l, Drer\slc6a5, Drer\si:ch211-132b12.1, Drer\slc6a4a, Drer\slc6a6b" - "Cele\snf-5, Cele\snf-12, Cele\snf-9, Cele\snf-6, Cele\snf-3, Cele\snf-2, Cele\dat-1, Cele\snf-7, Cele\snf-11, Cele\mod-5" "Xtro\slc6a8, Xtro\slc6a13, Xtro\LOC100127682, Xtro\slc6a5, Xtro\slc6a14.2, Xtro\slc6a9, Xtro\slc6a19, Xtro\slc6a16, Xtro\slc6a3, Xtro\slc6a15, Xtro\slc6a1, Xtro\slc6a4, Xtro\slc6a6, Xtro\slc6a12, Xtro\slc6a17, Xtro\slc6a7, Xtro\slc6a2" "Mmus\Slc6a2, Mmus\Slc6a4, Mmus\Slc6a17, Mmus\Slc6a9, Mmus\Slc6a1, Mmus\Slc6a11, Mmus\Slc6a6, Mmus\Slc6a20a, Mmus\Slc6a19, Mmus\Slc6a14, Mmus\Slc6a20b, Mmus\Slc6a3, Mmus\Slc6a8, Mmus\Slc6a18, Mmus\Slc6a5, Mmus\Slc6a12, Mmus\Slc6a15, Mmus\Slc6a13, Mmus\Slc6a7" "Hsap\SLC6A2, Hsap\SLC6A9, Hsap\SLC6A6, Hsap\SLC6A8, Hsap\SLC6A4, Hsap\SLC6A20, Hsap\SLC6A15, Hsap\SLC6A11, Hsap\SLC6A19, Hsap\SLC6A13, Hsap\SLC6A1, Hsap\SLC6A14, Hsap\SLC6A17, Hsap\SLC6A5, Hsap\SLC6A18, Hsap\SLC6A12, Hsap\SLC6A3" viable FBgn0029091 CS-2 Chitin synthase 2 http://flybase.org/reports/FBgn0029091 protein_coding_gene chitin synthase activity ; GO:0004100 | inferred from biological aspect of ancestor with PANTHER:PTN001115588 cell wall chitin biosynthetic process ; GO:0006038 | inferred from biological aspect of ancestor with PANTHER:PTN001115588 cuticle chitin biosynthetic process ; GO:0006035 | inferred from biological aspect of ancestor with PANTHER:PTN001115600 cell periphery ; GO:0071944 | inferred from biological aspect of ancestor with PANTHER:PTN001115588 cell septum ; GO:0030428 | inferred from biological aspect of ancestor with PANTHER:PTN001115588 "CG7464, ChSA, DmeChSA, DmCS-2, CS-2, DmeCHS2, chitin synthase" "IPR004835:Chitin synthase, IPR029044:Nucleotide-diphospho-sugar transferases" CG7464 11-Aug-17 DroID_v2017_08 "Drer\chs1, Drer\si:ch211-264e16.2, Drer\mpc1, Drer\has3, Drer\has1, Drer\has2, Drer\si:ch211-264e16.1, Drer\si:ch211-219a15.4" "Scer\CHS2, Scer\CHS1, Scer\CHS3" "Cele\chs-1, Cele\chs-2" "Xtro\has1, Xtro\has2, Xtro\has3" "Mmus\Has2, Mmus\Has1, Mmus\Has3" "Hsap\HAS2, Hsap\HAS1, Hsap\HAS3" viable FBgn0065973 invader3\ORF invader3 element ORF http://flybase.org/reports/FBgn0065973 transposable_element_gene - - - invader3\ORF - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067366 l(2)NC30 lethal (2) NC30 http://flybase.org/reports/FBgn0067366 gene - - - "NC30, l(2)NC30" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060783 l(3)S059913a lethal (3) S059913a http://flybase.org/reports/FBgn0060783 gene - - - "0599/13, l(3)S059913a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031449 CG31689 - http://flybase.org/reports/FBgn0031449 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CG9892, CG31689" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG31689 11-Aug-17 DroID_v2017_08 "Drer\abcg2a, Drer\abcg5, Drer\abcg4a, Drer\abcg8, Drer\abcg4b, Drer\abcg1, Drer\abcg2b" "Scer\PDR12, Scer\ADP1, Scer\YOL075C, Scer\PDR10, Scer\PDR18" "Cele\wht-1, Cele\abch-1, Cele\wht-4" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg5, Mmus\Abcg4, Mmus\Abcg8, Mmus\Abcg2, Mmus\Abcg1, Mmus\Abcg3" "Hsap\ABCG5, Hsap\ABCG1, Hsap\ABCG4, Hsap\ABCG8" viable FBgn0265163 CR44232 - http://flybase.org/reports/FBgn0265163 non_protein_coding_gene - - - CR44232 - CR44232 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267038 CR45482 - http://flybase.org/reports/FBgn0267038 non_protein_coding_gene - - - CR45482 - CR45482 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060821 l(3)S052318b lethal (3) S052318b http://flybase.org/reports/FBgn0060821 gene - - - "0523/18, l(3)S052318b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004934 a(3)48 abnormal abdomen (3) 48 http://flybase.org/reports/FBgn0004934 - gene - - - a(3)48 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,maternal effect,recessive,good" "tergite,sternite" FBgn0050380 CG30380 - http://flybase.org/reports/FBgn0050380 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30380 - CG30380 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085297 CG34268 - http://flybase.org/reports/FBgn0085297 protein_coding_gene - - - CG34268 - CG34268 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010630 l(2)06935 lethal (2) 06935 http://flybase.org/reports/FBgn0010630 - gene - - - l(2)06935 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031010 CG8028 - http://flybase.org/reports/FBgn0031010 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 renal tubular secretion ; GO:0097254 | inferred from expression pattern response to toxic substance ; GO:0009636 | inferred from expression pattern integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "CG8028, MCT" "IPR020846:Major facilitator superfamily domain, IPR011701:Major facilitator superfamily" CG8028 11-Aug-17 DroID_v2017_08 "Drer\zgc:114041, Drer\si:ch211-234h8.7, Drer\slc16a8, Drer\slc16a13, Drer\slc16a7, Drer\slc16a12b, Drer\slc16a5b" "Scer\ATG22, Scer\MCH4, Scer\MCH2, Scer\ESBP6, Scer\MCH5" "Cele\mct-4, Cele\Y59A8B.21, Cele\slcf-1, Cele\mct-3" - "Mmus\Slc16a6, Mmus\Slc16a12, Mmus\Slc16a4, Mmus\Slc16a13, Mmus\Slc16a7" "Hsap\SLC16A3, Hsap\SLC16A6, Hsap\SLC16A13, Hsap\SLC16A11, Hsap\SLC16A12, Hsap\SLC16A7, Hsap\SLC16A1" viable FBgn0005466 l(1)ts108 lethal (1) ts108 http://flybase.org/reports/FBgn0005466 - gene - - - l(1)ts108 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0002150 l(2)KE39 lethal (2) KE39 http://flybase.org/reports/FBgn0002150 - gene - - - l(2)KE39 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005753 l(1)TK308 lethal (1) TK308 http://flybase.org/reports/FBgn0005753 - gene - - - "l308, l(1)TK308" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0027277 l(1)G0199 lethal (1) G0199 http://flybase.org/reports/FBgn0027277 - gene - - - l(1)G0199 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028868 CG4701 - http://flybase.org/reports/FBgn0028868 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | inferred from sequence or structural similarity" - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity "DmDM19DC4Z, BG:DS06874.3, CG4701" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4701 11-Aug-17 DroID_v2017_08 "Drer\atad1a, Drer\atad1b" Scer\MSP1 Cele\mspn-1 Xtro\atad1 Mmus\Atad1 Hsap\ATAD1 DRSC01952 IK -1.732018369 -1.201498119 -1.416515964 -1.144379224 0.060050948 1.918188962 FBgn0035549 CG11346 - http://flybase.org/reports/FBgn0035549 protein_coding_gene - - - CG11346 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002753 mit(1)3 mitotic 3 http://flybase.org/reports/FBgn0002753 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0004482 l(1)air9 lethal aberrant immune response 9 http://flybase.org/reports/FBgn0004482 - gene - - - "air9, l(1)air[9], l(1)air9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,melanotic mass phenotype" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass,embryonic/larval lymph gland" FBgn0026866 Gsc::h Gsc::h http://flybase.org/reports/FBgn0026866 - engineered_fusion_gene - - - Gsc::h - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female" FBgn0067809 anon-N4 anon-N4 http://flybase.org/reports/FBgn0067809 gene - - - "N4, anon-N4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010579 l(2)38EFd lethal (2) 38EFd http://flybase.org/reports/FBgn0010579 FBgn0025167 gene - - - "l(2)04530, l(2)38EFd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043596 E(ro[DOM])1777 E(ro[DOM])1777 http://flybase.org/reports/FBgn0043596 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available E(ro[DOM])1777 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0031970 CG7227 - http://flybase.org/reports/FBgn0031970 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 CG7227 IPR002159:CD36 family CG7227 11-Aug-17 DroID_v2017_08 "Drer\scarb2, Drer\scarb1, Drer\LOC564077, Drer\cd36" - "Cele\scav-1, Cele\scav-4, Cele\scav-2, Cele\scav-3" "Xtro\scarb1, Xtro\cd36, Xtro\scarb2" "Mmus\Scarb2, Mmus\Cd36, Mmus\Scarb1" "Hsap\CD36, Hsap\SCARB2, Hsap\SCARB1" viable FBgn0037467 Ufl1 UFM1 specific ligase 1 http://flybase.org/reports/FBgn0037467 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay "CG1104, Ufl1, UFL1" IPR018611:E3 UFM1-protein ligase 1 CG1104 11-Aug-17 DroID_v2017_08 Drer\ufl1 - Cele\ufl-1 Xtro\ufl1 Mmus\Ufl1 Hsap\UFL1 viable FBgn0040506 ACXE ACXE http://flybase.org/reports/FBgn0040506 protein_coding_gene adenylate cyclase activity ; GO:0004016 | inferred from sequence model adenylate cyclase activity ; GO:0004016 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG17178, AC, DACXE, ACXE" "IPR029787:Nucleotide cyclase, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR032628:Adenylate cyclase, N-terminal" CG17178 11-Aug-17 DroID_v2017_08 "Drer\adcy3a, Drer\adcy6b, Drer\adcy7, Drer\adcy2b, Drer\si:ch211-132f19.7, Drer\si:dkey-206f10.1, Drer\adcy2a, Drer\adcy1b, Drer\adcy1a, Drer\adcy8, Drer\adcy5, Drer\adcy6a" - "Cele\acy-4, Cele\acy-2" "Xtro\adcy4, Xtro\adcy6, Xtro\adcy1, Xtro\adcy7, Xtro\dnajc27" "Mmus\Adcy1, Mmus\Adcy2, Mmus\Adcy5, Mmus\Adcy8, Mmus\Adcy4, Mmus\Adcy7, Mmus\Adcy6, Mmus\Adcy3" "Hsap\ADCY5, Hsap\ADCY8, Hsap\ADCY4, Hsap\ADCY6, Hsap\ADCY3, Hsap\ADCY2, Hsap\ADCY7, Hsap\ADCY1" FBgn0001313 kl-2 male fertility factor kl2 http://flybase.org/reports/FBgn0001313 "FBgn0039968, FBgn0058438, FBan0017866" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity with protein_id:CAB99316 traceable author statement ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 inner dynein arm ; GO:0036156 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 dynein complex ; GO:0030286 | traceable author statement "kl-2, Lms2, CG40438, CG17866, kl2, DHC3A" "IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain, IPR003593:AAA+ ATPase domain" CG17866 11-Aug-17 DroID_v2017_08 "Drer\dnah1, Drer\dnah12, Drer\dnah7, Drer\si:dkeyp-86b9.1, Drer\wu:fj30b09, Drer\dnah3, Drer\dnah7l, Drer\dnah9l, Drer\dync1h1, Drer\dnah2, Drer\si:dkeyp-87a6.1" Scer\DYN1 - "Xtro\dnah2, Xtro\dnah7, Xtro\dnah14" "Mmus\Dnah9, Mmus\Dnah6, Mmus\Dnah12, Mmus\Dnah7b, Mmus\Dnah11, Mmus\Dnah2, Mmus\Dnah3, Mmus\Dnah5, Mmus\Dnhd1, Mmus\Dnah17, Mmus\Dnah10, Mmus\Dync1h1, Mmus\Dnah7a, Mmus\Dnah1, Mmus\Dnah7c, Mmus\Dnah8, Mmus\Dync2h1" "Hsap\CCDC88B, Hsap\DNAH10, Hsap\DNHD1, Hsap\DNAH12, Hsap\DNAH17, Hsap\DNAH7, Hsap\DNAH11, Hsap\DNAH5, Hsap\DYNC2H1, Hsap\DYNC1H1, Hsap\DNAH6, Hsap\DNAH3, Hsap\DNAH9, Hsap\DNAH1, Hsap\DNAH2, Hsap\DNAH8" "viable,learning defective,male sterile" "Nebenkern,spermatid,spermatocyte" FBgn0067913 Egfr::kek1 Egfr::kek1 http://flybase.org/reports/FBgn0067913 engineered_fusion_gene - - - Egfr::kek1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "egg,dorsal appendage,chorion,eye,ommatidium" FBgn0038767 trem trade embargo http://flybase.org/reports/FBgn0038767 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype meiotic DNA double-strand break formation involved in reciprocal meiotic recombination ; GO:0010780 | inferred from mutant phenotype meiotic DNA double-strand break processing involved in reciprocal meiotic recombination ; GO:0010705 | inferred from mutant phenotype nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "trem, CG4413" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG4413 11-Aug-17 DroID_v2017_08 "Drer\wt1b, Drer\zgc:171929, Drer\ovol1, Drer\wt1a" Scer\AZF1 "Cele\pag-3, Cele\lin-48, Cele\hinf-1, Cele\M03D4.4, Cele\Y55F3AM.14, Cele\C04F5.9, Cele\klf-2" "Xtro\ovol1, Xtro\ovol2" "Mmus\Zfp758, Mmus\Mzf1, Mmus\Zfp735, Mmus\Zkscan5, Mmus\Zscan29, Mmus\Zfp62, Mmus\Zscan25, Mmus\Zfp352, Mmus\Zkscan2, Mmus\Zfp13, Mmus\Ovol2, Mmus\Zkscan7, Mmus\Zfp449, Mmus\Zfp444, Mmus\Zfp93, Mmus\Wt1, Mmus\Zkscan3, Mmus\Zfp869, Mmus\Zfp945, Mmus\Gm14432, Mmus\Zkscan14, Mmus\Zfp202, Mmus\Zfp397, Mmus\Gzf1, Mmus\5730507C01Rik, Mmus\Klf17, Mmus\Ovol3, Mmus\E430018J23Rik, Mmus\Zscan21, Mmus\Zfp12, Mmus\Zscan20, Mmus\Zkscan1, Mmus\Zfp296, Mmus\Zfp566, Mmus\Zfp213, Mmus\Zscan26, Mmus\Zkscan8, Mmus\Klf1, Mmus\Zfp263, Mmus\Zscan2, Mmus\Zkscan17, Mmus\Zkscan16, Mmus\Zfp113, Mmus\Ovol1, Mmus\Zscan22, Mmus\Zfp984, Mmus\Gm3604, Mmus\Zkscan6, Mmus\Zfp558, Mmus\Gm13212, Mmus\Zfp612, Mmus\Zfp174, Mmus\Zscan12, Mmus\Zfp809, Mmus\Zfp27, Mmus\Zkscan4, Mmus\Zfp708, Mmus\Zfp92" "Hsap\ZNF296, Hsap\ZNF70, Hsap\ZNF492, Hsap\ZNF852, Hsap\ZNF558, Hsap\ZNF599, Hsap\ZNF394, Hsap\ZNF572, Hsap\ZNF595, Hsap\ZFP28, Hsap\ZNF816, Hsap\ZNF98, Hsap\ZNF485, Hsap\ZNF730, Hsap\OVOL2, Hsap\OVOL1, Hsap\KLF17, Hsap\ZSCAN29, Hsap\ZNF233, Hsap\RBAK-RBAKDN, Hsap\ZNF721, Hsap\ZNF792, Hsap\ZNF785, Hsap\ZNF254, Hsap\ZNF468, Hsap\ZNF107, Hsap\ZSCAN32, Hsap\ZNF160, Hsap\ZNF28, Hsap\OVOL3, Hsap\ZNF764, Hsap\WT1, Hsap\ZNF281, Hsap\ZNF568, Hsap\ZNF850, Hsap\ZNF766, Hsap\ZSCAN30, Hsap\ZSCAN2, Hsap\ZSCAN31, Hsap\ZNF480, Hsap\KLF1, Hsap\ZNF845, Hsap\ZNF891, Hsap\ZNF570, Hsap\ZNF117, Hsap\ZNF793, Hsap\ZNF528, Hsap\ZNF25, Hsap\ZNF527, Hsap\ZNF526, Hsap\ZNF708, Hsap\ZNF679, Hsap\ZNF675, Hsap\ZNF707, Hsap\ZNF43, Hsap\ZNF211, Hsap\ZNF582, Hsap\ZNF610, Hsap\ZNF761" "meiotic cell cycle defective,cold sensitive,viable" DRSC15575 E -0.583437492 0.034892115 -1.574234871 -0.17542329 -0.610415479 -0.025590714 FBgn0020277 lush lush http://flybase.org/reports/FBgn0020277 - protein_coding_gene odorant binding ; GO:0005549 | inferred from electronic annotation with InterPro:IPR006170 odorant binding ; GO:0005549 | non-traceable author statement ethanol binding ; GO:0035276 | NOT inferred from direct assay odorant binding ; GO:0005549 | traceable author statement diphenyl phthalate binding ; GO:0035274 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 dibutyl phthalate binding ; GO:0035275 | inferred from direct assay courtship behavior ; GO:0007619 | inferred from mutant phenotype response to ethanol ; GO:0045471 | traceable author statement response to pheromone ; GO:0019236 | inferred from direct assay inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from direct assay inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 response to ethanol ; GO:0045471 | NOT inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "lush, obp76a, Obp76a, 76a, 76c(LUSH), LUSH, 76c, CG8807, DmelObp76a, Lush" IPR006170:Pheromone/general odorant binding protein CG8807 11-Aug-17 DroID_v2017_08 - - "Cele\T14G12.12, Cele\K07G6.1, Cele\C35A11.2" - - - "neurophysiology defective,courtship behavior defective,wild-type,smell perception defective,viable,fertile,recessive,neuroanatomy defective" "olfactory receptor neuron,T1 neuron,T2 neuron,pit sensillum T1,pit sensillum T2,adult olfactory receptor neuron Or67d" FBgn0005700 l(1)TK103 lethal (1) TK103 http://flybase.org/reports/FBgn0005700 - gene - - - "l103, l(1)TK103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "eye,lamina" FBgn0027596 Kank Kank http://flybase.org/reports/FBgn0027596 FBgn0043818 protein_coding_gene microtubule plus-end binding ; GO:0051010 | inferred from direct assay neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay microtubule plus-end ; GO:0035371 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay muscle tendon junction ; GO:0005927 | inferred from direct assay "BEST:GH19041, BcDNA:GH03482, CG10249, Kank, kank, dKank" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR021939:Kank N-terminal motif" CG10249 11-Aug-17 DroID_v2017_08 "Drer\kank2, Drer\kank4, Drer\kank1, Drer\kank3, Drer\kank1b" - Cele\vab-19 "Xtro\kank2, Xtro\kank1, Xtro\kank4, Xtro\kank3" "Mmus\Kank4, Mmus\Kank1, Mmus\Kank3, Mmus\Kank2" "Hsap\KANK2, Hsap\KANK3, Hsap\KANK1, Hsap\KANK4" viable FBgn0034122 CG15711 - http://flybase.org/reports/FBgn0034122 protein_coding_gene - - - CG15711 IPR031754:Protein of unknown function DUF4736 CG15711 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015895 anon-95EFa anon-95EFa http://flybase.org/reports/FBgn0015895 - gene - - - anon-95EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259817 SteXh:CG42398 SteXh:CG42398 http://flybase.org/reports/FBgn0259817 protein_coding_gene "protein kinase regulator activity ; GO:0019887 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150 protein kinase regulator activity ; GO:0019887 | inferred from sequence orthology with SGD:S000005565" - "protein kinase CK2 complex ; GO:0005956 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150 protein kinase CK2 complex ; GO:0005956 | inferred from sequence orthology with SGD:S000005565" "SteXh:CG42398, RR41752, CG42398" "IPR016149:Casein kinase II, regulatory subunit, alpha-helical, IPR000704:Casein kinase II, regulatory subunit" CG42398 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" - Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0083244 EP1200 EP1200 http://flybase.org/reports/FBgn0083244 gene - - - EP1200 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085610 CG41316 - http://flybase.org/reports/FBgn0085610 protein_coding_gene - - - CG41316 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045063 fdl fused lobes http://flybase.org/reports/FBgn0045063 protein_coding_gene beta-N-acetylgalactosaminidase activity ; GO:0032428 | NOT inferred from direct assay beta-N-acetylhexosaminidase activity ; GO:0004563 | inferred from sequence or structural similarity with UniProtKB:P49010 beta-N-acetylglucosaminidase activity ; GO:0016231 | inferred from direct assay protein deglycosylation ; GO:0006517 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype chitin catabolic process ; GO:0006032 | NOT inferred from direct assay N-glycan processing ; GO:0006491 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | colocalizes_with inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay Golgi apparatus ; GO:0005794 | colocalizes_with inferred from direct assay "CG8824, l(2)k17040, fdl, Fdl, FDL" "IPR025705:Beta-hexosaminidase, IPR015883:Glycoside hydrolase family 20, catalytic domain, IPR017853:Glycoside hydrolase superfamily, IPR029018:Chitobiase/beta-hexosaminidase domain 2-like, IPR029019:Beta-hexosaminidase, eukaryotic type, N-terminal" CG8824 11-Aug-17 DroID_v2017_08 "Drer\hexa, Drer\hexb" - Cele\hex-1 Xtro\hexb "Mmus\Hexb, Mmus\Hexa" "Hsap\HEXB, Hsap\HEXA" "lethal,recessive,viable,neuroanatomy defective,cell lethalcell lethal,somatic clone" "protocerebral bridge,mushroom body beta-lobe" FBgn0037295 dpr16 defective proboscis extension response 16 http://flybase.org/reports/FBgn0037295 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 extracellular region ; GO:0005576 | inferred from sequence model "CG12591, Dpr-16, CT34444, dpr16, Dpr16, mdcds_51595" "IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype" CG12591 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-264f5.6, Drer\si:dkey-65b12.12, Drer\LOC101885444, Drer\LOC100333196" - Cele\zig-8 "Xtro\cadm2, Xtro\nfasc, Xtro\obsl1" "Mmus\Cadm2, Mmus\Cadm4, Mmus\Cadm1, Mmus\Cadm3" "Hsap\CADM1, Hsap\CADM4, Hsap\CADM3, Hsap\CADM2" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0038571 CG7215 - http://flybase.org/reports/FBgn0038571 protein_coding_gene - - - "CG32920, CG7215" "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG7215 11-Aug-17 DroID_v2017_08 "Drer\faua, Drer\zgc:56596, Drer\faub, Drer\ubc, Drer\isg15, Drer\zfand4" "Scer\DSK2, Scer\UBI4" "Cele\K08C9.7, Cele\F34H10.1, Cele\ubl-1, Cele\K10C2.12" "Xtro\ubc, Xtro\zfand4, Xtro\fau, Xtro\ubl4a" "Mmus\Oas1g, Mmus\Zfand4, Mmus\Oas2, Mmus\Gm44504, Mmus\Isg15, Mmus\Oas1a, Mmus\Ubd, Mmus\Ubl4a, Mmus\Oasl1, Mmus\Oasl2, Mmus\Fau, Mmus\Oas3, Mmus\Ubl4b, Mmus\Ubb" "Hsap\OASL, Hsap\ISG15, Hsap\OAS3, Hsap\UBL4B, Hsap\UBB, Hsap\ZFAND4, Hsap\OAS2, Hsap\UBC, Hsap\UBD, Hsap\OAS1, Hsap\UBL4A" FBgn0015408 l(1)12Bc lethal (1) 12Bc http://flybase.org/reports/FBgn0015408 - gene - - - l(1)12Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036500 CG7275 - http://flybase.org/reports/FBgn0036500 protein_coding_gene - "neurogenesis ; GO:0022008 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000523215" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000523215 Cul4-RING E3 ubiquitin ligase complex ; GO:0080008 | inferred from biological aspect of ancestor with PANTHER:PTN000523215 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000523215 CG7275 "IPR001680:WD40 repeat, IPR007287:Sof1-like protein, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG7275 11-Aug-17 DroID_v2017_08 Drer\dcaf13 Scer\SOF1 Cele\ZK430.7 Xtro\dcaf13 Mmus\Dcaf13 Hsap\DCAF13 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC10796 K -0.402897776 -0.030676213 0.835117667 0.021172666 -1.515904101 -0.301688977 FBgn0033902 eIF3m eukaryotic translation initiation factor 3 subunit m http://flybase.org/reports/FBgn0033902 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR027528 translation initiation factor binding ; GO:0031369 | inferred from sequence or structural similarity with MGI:MGI:1351744 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:2001272 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype translation ; GO:0006412 | inferred from sequence or structural similarity with MGI:MGI:1351744 protein secretion ; GO:0009306 | inferred from mutant phenotype cytoplasmic translational initiation ; GO:0002183 | inferred from biological aspect of ancestor with PANTHER:PTN000394291 sperm individualization ; GO:0007291 | inferred from mutant phenotype regulation of apoptotic signaling pathway ; GO:2001233 | inferred from mutant phenotype inferred from physical interaction with Dronc inferred from physical interaction with Dark activation of cysteine-type endopeptidase activity ; GO:0097202 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with MGI:MGI:1351744 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000394291 cytosol ; GO:0005829 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay investment cone ; GO:0070865 | inferred from direct assay apoptosome ; GO:0043293 | inferred from direct assay "CG8309, TANGO7, anon-EST:Posey67, anon-EST:Posey76, eIF3M, Tango 7, Tango7, tango7, Tng7, eIF3m" "IPR000717:Proteasome component (PCI) domain, IPR011989:Armadillo-like helical, IPR027528:Eukaryotic translation initiation factor 3 subunit M, IPR011991:Winged helix-turn-helix DNA-binding domain" CG8309 11-Aug-17 DroID_v2017_08 "Drer\zgc:114126, Drer\eif3m" Scer\RPN9 Cele\cif-1 Xtro\eif3m Mmus\Eif3m Hsap\EIF3M "viable,male sterile,visible,partially lethal - majority live,short lived,lethal - all die before end of first instar larval stage" "wing,cystic bulge,investment cone" DRSC26908 IEK -1.692700655 -1.572819397 -1.290113461 -2.527817574 0.138779391 2.84422948 FBgn0026606 Act79B::Act88F Act79B::Act88F http://flybase.org/reports/FBgn0026606 - engineered_fusion_gene - - - Act79B::Act88F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035025 uri unconventional prefoldin RPB5 interactor http://flybase.org/reports/FBgn0035025 protein_coding_gene chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000387656 phosphatase inhibitor activity ; GO:0019212 | inferred from direct assay RNA polymerase II transcription corepressor activity ; GO:0001106 | inferred from biological aspect of ancestor with PANTHER:PTN000387656 spermatogenesis ; GO:0007283 | inferred from mutant phenotype negative regulation of phosphatase activity ; GO:0010923 | inferred from biological aspect of ancestor with PANTHER:PTN000387656 negative regulation of catalytic activity ; GO:0043086 | inferred from direct assay "cytoplasm ; GO:0005737 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from biological aspect of ancestor with PANTHER:PTN000387656" "CG11416, dURI, uri, ori" IPR004127:Prefoldin alpha-like CG11416 11-Aug-17 DroID_v2017_08 Drer\uri1 - Cele\uri-1 Xtro\uri1 Mmus\Uri1 Hsap\URI1 "visible,viable,fertile,lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage" "wing,testis,ovary,mesothoracic tergum" DRSC04111 IE -0.110019592 -3.651999484 -0.272674164 -2.206205808 -1.126885177 -1.015201786 FBgn0025935 fl(1)35 female lethal (1) 35 http://flybase.org/reports/FBgn0025935 - gene - - - "fl-35, fl(1)35" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,female,reduced,female fertile" FBgn0053121 Spn28Db Serpin 28Db http://flybase.org/reports/FBgn0053121 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG12318, Spn28Db, CG33121" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG33121 11-Aug-17 DroID_v2017_08 "Drer\serpina1l, Drer\si:ch1073-416d2.3, Drer\serpinh1a, Drer\serpinb1l2, Drer\zgc:174260, Drer\serpine1, Drer\serpind1, Drer\serpinh2, Drer\serpinc1, Drer\serpinb1l3, Drer\serpinb1, Drer\serpini1, Drer\serpinh1b, Drer\serpina7, Drer\serpina10a, Drer\serpinb1l4, Drer\serpine2, Drer\si:ch211-186e20.7, Drer\serpine3, Drer\zgc:173729, Drer\serpinb1l1, Drer\zgc:174259" - "Cele\srp-1, Cele\srp-8, Cele\srp-2, Cele\srp-7, Cele\srp-6, Cele\srp-3" "Xtro\serpina3m, Xtro\serpinb11, Xtro\serpina3k, Xtro\agt, Xtro\serpinb1, Xtro\serpine1, Xtro\serpinc1, Xtro\serpini1, Xtro\serpina1, Xtro\serpina10, Xtro\serpinb4, Xtro\serpind1, Xtro\serpina3, Xtro\serpinb6, Xtro\serpini2, Xtro\serpinb5, Xtro\serpine2" "Mmus\Serpinb13, Mmus\Serpinb3c, Mmus\Serpinb6d, Mmus\Serpina1a, Mmus\Serpinb9d, Mmus\Serpina1d, Mmus\Serpina11, Mmus\Serpinb1c, Mmus\Serpinb9, Mmus\Serpinb11, Mmus\Serpinb5, Mmus\Serpinb1a, Mmus\Serpinb6e, Mmus\Serpinh1, Mmus\Serpinb3d, Mmus\Serpina1e, Mmus\Serpinb1b, Mmus\Serpinb10, Mmus\Serpinb12, Mmus\Serpina5, Mmus\Serpina6, Mmus\Serpina3k, Mmus\Serpinb9f, Mmus\Serpina1c, Mmus\Serpini1, Mmus\Serpinb2, Mmus\Serpina7, Mmus\Serpina16, Mmus\Serpinc1, Mmus\Serpinb9g, Mmus\Serpine2, Mmus\Serpini2, Mmus\Serpinb9e, Mmus\Serpind1, Mmus\Serpinb3b, Mmus\Serpina3a, Mmus\Serpina3i, Mmus\Serpina3f, Mmus\Serpina3c, Mmus\Serpina3j, Mmus\Serpina10, Mmus\Serpinb7, Mmus\Serpina3g, Mmus\Serping1, Mmus\Serpina3n, Mmus\Serpina9, Mmus\Serpinb9b, Mmus\Serpinb6a, Mmus\Serpinb8, Mmus\Serpine1, Mmus\Serpinb9c, Mmus\Serpinb6b, Mmus\Serpina12, Mmus\Serpinb3a, Mmus\Serpinb6c, Mmus\Gm11397, Mmus\Serpine3" "Hsap\SERPINA5, Hsap\SERPIND1, Hsap\SERPINB10, Hsap\SERPINB8, Hsap\SERPINB2, Hsap\SERPINB1, Hsap\SERPINA11, Hsap\HMSD, Hsap\SERPINA10, Hsap\SERPINA9, Hsap\SERPINE2, Hsap\SERPINB9, Hsap\SERPINI1, Hsap\SERPINB5, Hsap\SERPINB7, Hsap\SERPINA4, Hsap\SERPINE1, Hsap\SERPINB4, Hsap\SERPINH1, Hsap\SERPINA7, Hsap\SERPINA3, Hsap\SERPING1, Hsap\SERPINB3, Hsap\SERPINB6, Hsap\SERPINB11, Hsap\SERPINB12, Hsap\SERPINA6, Hsap\SERPINI2, Hsap\SERPINA12, Hsap\SERPINE3, Hsap\SERPINC1, Hsap\SERPINA1, Hsap\SERPINB13" viable FBgn0051807 CG31807 - http://flybase.org/reports/FBgn0051807 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:25539 zinc ion binding ; GO:0008270 | inferred from sequence model protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:25539 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:25539 CG31807 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31807 11-Aug-17 DroID_v2017_08 Drer\rfwd3 - "Cele\T01G5.7, Cele\F19G12.1" Xtro\rfwd3 "Mmus\Rfwd3, Mmus\Rnf4" "Hsap\RFWD3, Hsap\RNF4" viable FBgn0022197 l(2)k04810 lethal (2) k04810 http://flybase.org/reports/FBgn0022197 - gene - - - l(2)k04810 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028654 anon-47Eb anon-47Eb http://flybase.org/reports/FBgn0028654 gene - - - "5A1, anon-47Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034437 CG10051 - http://flybase.org/reports/FBgn0034437 protein_coding_gene - - - CG10051 IPR007484:Peptidase M28 CG10051 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\PFF1, Scer\APE3, Scer\YDR415C, Scer\VPS70" "Cele\C44B7.11, Cele\B0495.7" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 FBgn0002079 l(2)49Fh lethal (2) 49Fh http://flybase.org/reports/FBgn0002079 - gene - - - "vr13, vr-13, l(2)vr13, l(2)49Fh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,non-suppressor of variegation,dominant" FBgn0084075 l(3)S133117 l(3)S133117 http://flybase.org/reports/FBgn0084075 gene - - - l(3)S133117 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025760 l(3)93DFb lethal (3) 93DFb http://flybase.org/reports/FBgn0025760 - gene - - - l(3)93DFb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051141 CG31141 - http://flybase.org/reports/FBgn0051141 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available CG31141 "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG31141 11-Aug-17 DroID_v2017_08 "Drer\elovl8b, Drer\elovl2, Drer\elovl4a, Drer\elovl7b, Drer\elovl8a, Drer\elovl4b, Drer\elovl7a, Drer\elovl5, Drer\elovl1a, Drer\elovl1b" "Scer\ELO1, Scer\ELO3, Scer\ELO2" Cele\elo-9 "Xtro\elovl2, Xtro\elovl1, Xtro\elovl7, Xtro\elovl5" "Mmus\Elovl1, Mmus\Elovl5, Mmus\Elovl2, Mmus\Elovl3, Mmus\Elovl4, Mmus\Elovl7" "Hsap\ELOVL3, Hsap\ELOVL5, Hsap\ELOVL2, Hsap\ELOVL7, Hsap\ELOVL1, Hsap\ELOVL4" viable FBgn0011170 l(1)291-5 lethal (1) 291-5 http://flybase.org/reports/FBgn0011170 FBgn0010199 gene - - - "291-5, l(1)291-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044444 GRT-G1-element\RTase GRT-G1-element RTase http://flybase.org/reports/FBgn0044444 transposable_element_gene - - - GRT-G1-element\RTase - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067042 V8 V8 http://flybase.org/reports/FBgn0067042 gene - - - V8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,lethal,viable" pigment cell FBgn0038470 CG18213 - http://flybase.org/reports/FBgn0038470 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG18213 "IPR002893:Zinc finger, MYND-type" CG18213 11-Aug-17 DroID_v2017_08 "Drer\smyd2b, Drer\smyd1a, Drer\smyd2a, Drer\smyd1b, Drer\smyd3" "Scer\SET6, Scer\SET5" "Cele\set-30, Cele\set-3, Cele\set-18, Cele\set-10" Xtro\smyd1 "Mmus\Smyd3, Mmus\Smyd2, Mmus\Smyd1, Mmus\Zmynd15" "Hsap\ZMYND15, Hsap\SMYD1, Hsap\SMYD3, Hsap\SMYD2" viable FBgn0005246 l(3)R159 lethal of Roberts 159 http://flybase.org/reports/FBgn0005246 - gene - - - "l(3)B159, l(3)R159" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0262082 m::tyn miniature::trynity http://flybase.org/reports/FBgn0262082 engineered_fusion_gene - - - m::tyn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032658 CG5681 - http://flybase.org/reports/FBgn0032658 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5681 - CG5681 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260284 GSd425 - http://flybase.org/reports/FBgn0260284 gene - - - GSd425 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031110 Obp19b Odorant-binding protein 19b http://flybase.org/reports/FBgn0031110 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "19b, CG1670, anon-WO0140519.23, Obp19b, DmelObp19b, o19b" IPR006170:Pheromone/general odorant binding protein CG1670 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023429 l(3)98Fa lethal (3) 98Fa http://flybase.org/reports/FBgn0023429 - gene - - - l(3)98Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030997 CG7990 - http://flybase.org/reports/FBgn0030997 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7990 IPR019402:Frag1/DRAM/Sfk1 CG7990 11-Aug-17 DroID_v2017_08 Drer\pgap2 Scer\CWH43 "Cele\F49E12.12, Cele\Y11D7A.9, Cele\Y38F1A.8, Cele\F36H9.5, Cele\C14B9.3, Cele\ZK185.4, Cele\T23B12.5, Cele\tag-189" Xtro\pgap2 "Mmus\Cwh43, Mmus\Pgap2" "Hsap\PGAP2, Hsap\CWH43" "viable,fertile" FBgn0042146 CG18823 - http://flybase.org/reports/FBgn0042146 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 - - CG18823 IPR000504:RNA recognition motif domain CG18823 11-Aug-17 DroID_v2017_08 "Drer\ncoa5, Drer\si:ch211-216l23.2" - - "Xtro\LOC100145527, Xtro\ncoa5" Mmus\Ncoa5 - viable FBgn0034133 CG7813 - http://flybase.org/reports/FBgn0034133 protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000294648" ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000294648 "mitochondrial proton-transporting ATP synthase, stator stalk ; GO:0000274 | inferred from biological aspect of ancestor with PANTHER:PTN000294648" CG7813 "IPR008689:ATP synthase, F0 complex, subunit D, mitochondrial" CG7813 11-Aug-17 DroID_v2017_08 Drer\atp5h Scer\ATP7 Cele\atp-5 Xtro\atp5h Mmus\Atp5h Hsap\ATP5H viable FBgn0060456 l(3)S118602a lethal (3) S118602a http://flybase.org/reports/FBgn0060456 gene - - - "1186/02, l(3)S118602a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000344 compressed compressed http://flybase.org/reports/FBgn0000344 - gene - - - "com, compressed" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,poor,fertile" "adult head,eye,vibrissae,arista,humerus,wing" FBgn0034033 CG8204 - http://flybase.org/reports/FBgn0034033 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT23078, CG8204" "IPR007529:Zinc finger, HIT-type, IPR004172:L27 domain" CG8204 11-Aug-17 DroID_v2017_08 "Drer\znhit3, Drer\znhit6" "Scer\HIT1, Scer\BCD1" Cele\zhit-3 Xtro\znhit3 "Mmus\Znhit3, Mmus\Znhit6" "Hsap\ZNHIT6, Hsap\ZNHIT3" FBgn0053487 CR33487 - http://flybase.org/reports/FBgn0053487 pseudogene_attribute - - - "CG33487, CR33487" - CR33487 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267629 CR45967 - http://flybase.org/reports/FBgn0267629 non_protein_coding_gene - - - CR45967 - CR45967 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038860 Ice2 Interacts with the C terminus of ELL 2 http://flybase.org/reports/FBgn0038860 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available transcription elongation factor complex ; GO:0008023 | inferred from direct assay ELL-EAF complex ; GO:0032783 | inferred from physical interaction with Su(Tpl) "Ice2, CG10825" "IPR019535:Little elongation complex subunit 2 , C-terminal" CG10825 11-Aug-17 DroID_v2017_08 Drer\ice2 - - Xtro\ice2 Mmus\Ice2 Hsap\ICE2 "partially lethal - majority die,visible" trichogen cell DRSC14268 E -0.178072484 -0.41790253 -1.719977236 0.17463945 0.177733329 0.21193317 FBgn0005350 Spread-d Spread dominant http://flybase.org/reports/FBgn0005350 - gene - - - "Spr, Spread-d, Spread" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority live,male sterile,female fertile" wing FBgn0053229 CG33229 - http://flybase.org/reports/FBgn0053229 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32492, CG16971, CG33229" - CG33229 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum DRSC08497 I -1.53635951 0.120109057 -0.561526714 0.668348251 0.34529911 -0.046386457 FBgn0267190 CR45630 - http://flybase.org/reports/FBgn0267190 non_protein_coding_gene - - - "CR45630, Mgn4221" - CR45630 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060549 l(3)S098513b lethal (3) S098513b http://flybase.org/reports/FBgn0060549 gene - - - "0985/13, l(3)S098513b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039782 CG15539 - http://flybase.org/reports/FBgn0039782 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG15539-NE4, CG15539" "IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR011990:Tetratricopeptide-like helical domain, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG15539 11-Aug-17 DroID_v2017_08 "Drer\zgc:152670, Drer\p4ha1b, Drer\zgc:158254, Drer\p4ha3, Drer\p4ha2, Drer\p4htm, Drer\p4ha1a" - "Cele\C14E2.4, Cele\Y43F8B.19, Cele\phy-3, Cele\phy-2, Cele\phy-4" "Xtro\p4ha3, Xtro\p4ha1, Xtro\p4ha2" "Mmus\P4ha3, Mmus\P4ha1, Mmus\P4ha2, Mmus\P4htm" "Hsap\P4HTM, Hsap\P4HA3, Hsap\P4HA1, Hsap\P4HA2" viable FBgn0262022 CG42833 - http://flybase.org/reports/FBgn0262022 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42833 - CG42833 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029986 CG15332 - http://flybase.org/reports/FBgn0029986 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15332 IPR006610:Domain of unknown function DM7 CG15332 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0015254 M(2)126 M(2)126 http://flybase.org/reports/FBgn0015254 - gene - - - M(2)126 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,Minute" FBgn0259291 C446 - http://flybase.org/reports/FBgn0259291 gene - - - C446 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0069082 sirio sirio http://flybase.org/reports/FBgn0069082 gene - - - sirio - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile spermatocyte FBgn0267215 CR45655 - http://flybase.org/reports/FBgn0267215 non_protein_coding_gene - - - CR45655 - CR45655 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044024 PK4 Pocket 4 http://flybase.org/reports/FBgn0044024 gene - - - PK4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052006 CG32006 - http://flybase.org/reports/FBgn0052006 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "DmCg32006, BcDNA:RE51913, CG32006" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG32006 11-Aug-17 DroID_v2017_08 "Drer\foxc1a, Drer\foxj1a, Drer\foxe1, Drer\foxj1b, Drer\foxg1c, Drer\foxf2b, Drer\foxe3" "Scer\FKH2, Scer\FKH1, Scer\HCM1, Scer\FHL1" - "Xtro\foxa1, Xtro\foxe3, Xtro\foxe1" Mmus\Foxj1 "Hsap\FOXC2, Hsap\FOXJ1" viable FBgn0003067 Pepck Phosphoenolpyruvate carboxykinase http://flybase.org/reports/FBgn0003067 - protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR008209 phosphoenolpyruvate carboxykinase (GTP) activity ; GO:0004613 | inferred from sequence or structural similarity with UniProtKB:Q16822 gluconeogenesis ; GO:0006094 | inferred from sequence or structural similarity with UniProtKB:Q16822 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q16822 "143299_at, CG17725, Pepck, PEPCK, pepck, CG10924, dPEPCK, Dromel_CG17725_FBtr0086701_pepck_mORF, pepck1" "IPR018091:Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site, IPR013035:Phosphoenolpyruvate carboxykinase, C-terminal, IPR008209:Phosphoenolpyruvate carboxykinase, GTP-utilising, IPR008210:Phosphoenolpyruvate carboxykinase, N-terminal" CG17725 11-Aug-17 DroID_v2017_08 "Drer\pck2, Drer\pck1" - "Cele\pck-3, Cele\pck-1, Cele\pck-2" "Xtro\pck1, Xtro\pck2" "Mmus\Pck1, Mmus\Pck2" "Hsap\PCK2, Hsap\PCK1" " larval stage | first instar , larval stage | second instar "

late viable FBgn0264470 CR43878 - http://flybase.org/reports/FBgn0264470 non_protein_coding_gene - - - CR43878 - CR43878 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004673 dlg2 discs large 2 http://flybase.org/reports/FBgn0004673 - gene - - - "l(1)d.lg.-2, dlg2" - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval brain FBgn0040323 GNBP1 Gram-negative bacteria binding protein 1 http://flybase.org/reports/FBgn0040323 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with PGRP-SA (1->3)-beta-D-glucan binding ; GO:0001872 | inferred from direct assay lipopolysaccharide binding ; GO:0001530 | inferred from direct assay polysaccharide binding ; GO:0030247 | traceable author statement lipopolysaccharide binding ; GO:0001530 | traceable author statement signaling pattern recognition receptor activity ; GO:0008329 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from direct assay beta-glucanase activity ; GO:0052736 | NOT inferred from key residues carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000757 defense response to Gram-negative bacterium ; GO:0050829 | NOT inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | non-traceable author statement innate immune response ; GO:0045087 | non-traceable author statement defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype inferred from genetic interaction with PGRP-SA defense response to fungus ; GO:0050832 | NOT inferred from mutant phenotype immune response ; GO:0006955 | inferred from expression pattern innate immune response-activating signal transduction ; GO:0002758 | inferred from direct assay regulation of innate immune response ; GO:0045088 | inferred from direct assay peptidoglycan catabolic process ; GO:0009253 | inferred from direct assay anchored component of plasma membrane ; GO:0046658 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "GNBP1, DGNBP-1, GNBP, DGNBP1, CG6895, GNBP-1, GNBP 1" "IPR000757:Glycoside hydrolase family 16, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR031756:Beta-1,3-glucan-binding protein, N-terminal" CG6895 11-Aug-17 DroID_v2017_08 - "Scer\CRR1, Scer\CRH1, Scer\UTR2" Cele\Y53H1B.4 - - - "immune response defective,viable" FBgn0050239 tRNA:Glu-CTC-1-1 transfer RNA:Glutamic acid-CTC 1-1 http://flybase.org/reports/FBgn0050239 tRNA_gene - - - "tRNA:glu4:53A, tRNA:E4:53A, CR30239, tRNA:Glu, chr2R.trna25-GluCTC, tRNA:Glu-CTC-1-1, tRNA:CR30239, tRNA-Glu-CTC-1-1, GAG" - CR30239 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032482 Pect Phosphoethanolamine cytidylyltransferase http://flybase.org/reports/FBgn0032482 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR004821 biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004821 ethanolamine-containing compound metabolic process ; GO:0042439 | non-traceable author statement - "CG5547, PECT, Pect, pect" "IPR004821:Cytidyltransferase-like domain, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG5547 11-Aug-17 DroID_v2017_08 Drer\pcyt2 Scer\ECT1 "Cele\Y37E3.11, Cele\C39D10.3" Xtro\pcyt2 Mmus\Pcyt2 Hsap\PCYT2 viable adult heart FBgn0262355 CR43053 - http://flybase.org/reports/FBgn0262355 non_protein_coding_gene - - - "CG43053, CR43053, lincRNA.164" - CR43053 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039939 CG11231 - http://flybase.org/reports/FBgn0039939 protein_coding_gene - - - CG11231 - - 11-Aug-17 DroID_v2017_08 - - - - - Hsap\CRIPAK viable FBgn0011799 l(3)rJ880 lethal (3) rJ880 http://flybase.org/reports/FBgn0011799 - gene - - - l(3)rJ880 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027116 mei-P23 mei-P23 http://flybase.org/reports/FBgn0027116 - gene - - - mei-P23 - - 11-Aug-17 DroID_v2017_08 - - - - - - meiotic cell cycle defective FBgn0039258 beta4GalT7 beta-4-galactosyltransferase 7 http://flybase.org/reports/FBgn0039258 protein_coding_gene metal ion binding ; GO:0046872 | inferred from sequence or structural similarity with HGNC:924 galactosyltransferase activity ; GO:0008378 | inferred from direct assay galactosyltransferase activity ; GO:0008378 | non-traceable author statement xylosylprotein 4-beta-galactosyltransferase activity ; GO:0046525 | inferred from sequence or structural similarity with HGNC:930 heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement proteoglycan biosynthetic process ; GO:0030166 | inferred from sequence or structural similarity with HGNC:930 N-glycan processing ; GO:0006491 | inferred from direct assay proteoglycan biosynthetic process ; GO:0030166 | inferred from sequence or structural similarity with HGNC:924 chondroitin sulfate biosynthetic process ; GO:0030206 | non-traceable author statement Golgi apparatus ; GO:0005794 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG11780, dbeta4GalTI, Dbeta4GalT7, beta4GalT7, dbeta4GalT7, GalTI, beta4Gal-T7, beta4GalTI, GalT, betaGalT7, dGAGbeta4GalTI" "IPR003859:Beta-1,4-galactosyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases, IPR027995:Galactosyltransferase, N-terminal, IPR027791:Galactosyltransferase, C-terminal" CG11780 11-Aug-17 DroID_v2017_08 Drer\b4galt7 Scer\TMA20 Cele\sqv-3 Xtro\b4galt7 Mmus\B4galt7 Hsap\B4GALT7 embryonic stage -- adult stage "visible,lethal,viable" "wing,posterior compartment,eye,ommatidium,interommatidial bristle,dorsal compartment,wing vein L2,leg,distal" FBgn0016119 ATPsynCF6 "ATP synthase, coupling factor 6" http://flybase.org/reports/FBgn0016119 FBgn0064843 protein_coding_gene "hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from electronic annotation with InterPro:IPR008387, InterPro:IPR016349 ATPase activity ; GO:0016887 | contributes_to inferred from sequence or structural similarity with HGNC:847" "ATP synthesis coupled proton transport ; GO:0015986 | inferred from electronic annotation with InterPro:IPR008387, InterPro:IPR016349 lateral inhibition ; GO:0046331 | inferred from mutant phenotype proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P18859" "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from electronic annotation with InterPro:IPR008387, InterPro:IPR016349 mitochondrial proton-transporting ATP synthase, central stalk ; GO:0005756 | inferred from sequence or structural similarity with UniProtKB:P18859 mitochondrion ; GO:0005739 | inferred from direct assay" "CG4412, BcDNA:RH08870, ATPsyn-Cf6, ATPR, ATPsynCF6" "IPR008387:ATP synthase-coupling factor 6, mitochondrial" CG4412 11-Aug-17 DroID_v2017_08 "Drer\atp5j, Drer\si:dkey-22n8.3, Drer\si:ch211-140m22.7" - Cele\atp-4 Xtro\atp5j Mmus\Atp5j Hsap\ATP5J "visible,partially lethal - majority die,some die during pupal stage" chaeta FBgn0017426 anon-68Eb anon-68Eb http://flybase.org/reports/FBgn0017426 - gene - - - "T2, anon-68Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264953 Piezo Piezo http://flybase.org/reports/FBgn0264953 protein_coding_gene mechanically-gated ion channel activity ; GO:0008381 | inferred from direct assay cation channel activity ; GO:0005261 | inferred from biological aspect of ancestor with PANTHER:PTN000323131 detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype detection of mechanical stimulus ; GO:0050982 | inferred from biological aspect of ancestor with PANTHER:PTN000323131 positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype cellular response to mechanical stimulus ; GO:0071260 | inferred from mutant phenotype regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000323131 mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR027272 plasma membrane ; GO:0005886 | inferred from direct assay "CG44122, Piezo, CG8486, clone 1.32, anon-EST:Liang-1.32, DmPiezo, Dmpiezo, CG31608, OrfKD, CG18103, fos500, fos28F, piezo" "IPR027272:Piezo family, IPR031334:Piezo non-specific cation channel, R-Ras-binding domain, IPR031805:Piezo domain" CG44122 11-Aug-17 DroID_v2017_08 "Drer\piezo2, Drer\LOC100334952, Drer\si:dkey-11f4.7, Drer\piezo1, Drer\LOC101882709" - Cele\pezo-1 "Xtro\piezo1, Xtro\piezo2" "Mmus\Piezo2, Mmus\Piezo1" "Hsap\PIEZO2, Hsap\PIEZO1" FBgn0283712 LIMK1 LIM domain kinase 1 http://flybase.org/reports/FBgn0283712 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein kinase activity ; GO:0004672 | non-traceable author statement" establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern protein phosphorylation ; GO:0006468 | non-traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype inferred from genetic interaction with ct synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay compound eye development ; GO:0048749 | inferred from genetic interaction with mbt regulation of axonogenesis ; GO:0050770 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6613 "LIMK1, CG1848, agn, LimK, LIMK, limk1, LIM-kinase 1, Dlimk, D-LIMK1, Limk, dLIMK, DLIMK, limk, DLIMK1, D-Limk, dLIMK1, LimK1, LIMK-1, ag, ts398, l(1)11Af, limK1" "IPR000719:Protein kinase domain, IPR001478:PDZ domain, IPR001781:Zinc finger, LIM-type, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG1848 11-Aug-17 DroID_v2017_08 "Drer\limk2, Drer\limk1b, Drer\limk1a" - "Cele\T25B9.5, Cele\kin-21, Cele\K09B11.5, Cele\Y52D5A.2, Cele\lrk-1, Cele\Y69E1A.3" "Xtro\limk1, Xtro\limk2, Xtro\wnk3" "Mmus\Lrrk1, Mmus\Limk2, Mmus\Limk1" "Hsap\MAP3K21, Hsap\LIMK2, Hsap\LRRK1, Hsap\TESK2, Hsap\LIMK1" "lethal,heat sensitive,learning defective,mitotic cell cycle defective,locomotor behavior defective,female,smell perception defective" "nurse cell,heat sensitive,egg chamber,follicle cell,nodulus" FBgn0027938 trt trt http://flybase.org/reports/FBgn0027938 gene molecular_function ; GO:0003674 | no biological data available - - trt - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266446 CG45076 - http://flybase.org/reports/FBgn0266446 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45076, CG6544" - CG45076 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal" FBgn0003487 spot spot http://flybase.org/reports/FBgn0003487 - gene - - - spot - - 11-Aug-17 DroID_v2017_08 - - - - - - head FBgn0086051 snoRNA:Me28S-U2134a - http://flybase.org/reports/FBgn0086051 snoRNA_gene - - - "snoRNA:Me28S-U2134a, Me28S-Um2134a, Me28S-U2134a(DmSnR62), CR34680, DmSnR62, Dm_28S.018, Dm_28S.018a, DmSnR62a, DmSnR62b" - CR34680 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005239 l(3)R73 lethal of Roberts 73 http://flybase.org/reports/FBgn0005239 - gene - - - "l(3)B73, l(3)R73" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0040714 CG15391 - http://flybase.org/reports/FBgn0040714 protein_coding_gene - - - CG15391 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262743 Fs(2)Ket Female sterile (2) Ketel http://flybase.org/reports/FBgn0262743 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "protein import into nucleus ; GO:0006606 | inferred from genetic interaction with Pen NLS-bearing protein import into nucleus ; GO:0006607 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype ribosomal protein import into nucleus ; GO:0006610 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 protein import into nucleus ; GO:0006606 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | inferred from direct assay protein import into nucleus, translocation ; GO:0000060 | inferred from biological aspect of ancestor with PANTHER:PTN000055427" lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay nuclear periphery ; GO:0034399 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nucleoplasm ; GO:0005654 | inferred from direct assay P granule ; GO:0043186 | inferred from physical interaction with tud inferred from physical interaction with vas nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with EMBL:L38951 nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with protein_id:AAC41763 nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "Fs(2)Ket, impbeta, Ketel, imp-beta, ketel, 38E.11, dKap-beta, Ket, Hon, fs(2)lto2, fs(2)ltoHD43, fs(2)lo-B, Fs(2)Sz7, Fs(2)Sz6, Fs(2)Hon, CG2637, IMPbeta1, Kpnb1, kettle, Impbeta, MRE26, fs(2)Ket, Fs(2)ket" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR021133:HEAT, type 2" CG2637 11-Aug-17 DroID_v2017_08 Drer\kpnb1 Scer\KAP95 Cele\imb-1 Xtro\kpnb1 Mmus\Kpnb1 Hsap\KPNB1 DRSC03328 IE -2.383368857 -3.573191205 -0.065656654 -2.966234443 -0.665249481 0.394128967 FBgn0040854 CG15222 - http://flybase.org/reports/FBgn0040854 protein_coding_gene - - - CG15222 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005358 Su(w[a])B1 Suppressor of white-apricot B on 1 http://flybase.org/reports/FBgn0005358 - gene - - - Su(w[a])B1 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective FBgn0016766 anon-17Cc anon-17Cc http://flybase.org/reports/FBgn0016766 - gene - - - "C3, anon-17Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | early , adult stage | female " FBgn0025765 l(3)89De lethal (3) 89De http://flybase.org/reports/FBgn0025765 - gene - - - "l(3)M188, l(3)89De" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026064 KP78a KP78a http://flybase.org/reports/FBgn0026064 FBgn0022392 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:21680" microtubule cytoskeleton organization ; GO:0000226 | inferred from electronic annotation with InterPro:IPR033624 establishment of cell polarity ; GO:0030010 | inferred from electronic annotation with InterPro:IPR033624 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:21680 cellular_component ; GO:0005575 | no biological data available "CG6715, Kp78A, KP78A, KP78a" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR033624:Serine/threonine-protein kinase MARK/par1" CG6715 11-Aug-17 DroID_v2017_08 "Drer\mark1, Drer\mark3b, Drer\sik2a, Drer\mark3a, Drer\sik1, Drer\mark2a, Drer\mapk7, Drer\si:dkey-31m14.7, Drer\mark4a, Drer\prkaa1, Drer\sik2b, Drer\mark2b" "Scer\FRK1, Scer\PRR1, Scer\KIN2, Scer\KIN1, Scer\SNF1" "Cele\kin-29, Cele\par-1" "Xtro\mark3, Xtro\mark2, Xtro\mapk7, Xtro\prkaa1, Xtro\sik3, Xtro\sik2, Xtro\mark4, Xtro\mapk15, Xtro\prkaa2" "Mmus\Gm6729, Mmus\Sik2, Mmus\Gm5157, Mmus\Sik1, Mmus\Gm5174, Mmus\Smok3a, Mmus\Gm5891, Mmus\Mark3, Mmus\Gm7168, Mmus\Smok2a, Mmus\Gm6902, Mmus\Smok3b, Mmus\Gm14151, Mmus\1810024B03Rik, Mmus\Mapk7, Mmus\Gm10668, Mmus\Sik3, Mmus\Mark2, Mmus\Gm4565, Mmus\Prkaa2, Mmus\4921509C19Rik, Mmus\Gm14147, Mmus\Gm10662, Mmus\Mark1, Mmus\Gm4567, Mmus\Mark4, Mmus\Prkaa1, Mmus\Gm6176, Mmus\Gm4922, Mmus\Gm6882, Mmus\Smok2b" "Hsap\SIK2, Hsap\MARK1, Hsap\MARK2, Hsap\MARK4, Hsap\SIK3, Hsap\SIK1, Hsap\PRKAA1, Hsap\MARK3, Hsap\PRKAA2" viable FBgn0003449 snf sans fille http://flybase.org/reports/FBgn0003449 FBgn0005667 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sxl snRNA stem-loop binding ; GO:0035614 | inferred from direct assay U1 snRNA binding ; GO:0030619 | inferred from direct assay identical protein binding ; GO:0042802 | inferred from physical interaction with snf pre-mRNA intronic pyrimidine-rich binding ; GO:0097158 | inferred from direct assay U2 snRNA binding ; GO:0030620 | inferred from direct assay poly(U) RNA binding ; GO:0008266 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with pps "oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from direct assay mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000323 inferred from sequence or structural similarity with SGD:S000001448 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with HGNC:11151 RNA splicing ; GO:0008380 | traceable author statement heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype primary sex determination, soma ; GO:0007539 | non-traceable author statement regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype female germ-line sex determination ; GO:0019099 | non-traceable author statement oogenesis ; GO:0048477 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000052389 U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000001448 nucleus ; GO:0005634 | inferred by curator from GO:0000381 intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity with SGD:S000000323 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with HGNC:11151 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with HGNC:11151 inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Sxl "U2 snRNP, fs(1)1621, SNF, Snf, CG4528, SNF/D25, U2 snRNP B'' protein, liz, fs(1)A1621, snf1621, fs(1)A16121, snRNP B'', D25, snf, U1-A, snRNP-U1-A, U2B" IPR000504:RNA recognition motif domain CG4528 11-Aug-17 DroID_v2017_08 "Drer\snrpb2, Drer\rnpc3, Drer\snrpa" "Scer\MSL1, Scer\MUD1" "Cele\rnp-3, Cele\rnp-2" "Xtro\snrpa, Xtro\snrpb2, Xtro\rnpc3" "Mmus\Snrpb2, Mmus\Snrpa, Mmus\Rnpc3" "Hsap\SNRPA, Hsap\RNPC3, Hsap\SNRPB2" " adult stage | female , adult stage | male " embryonic stage -- adult stage "female sterile,dominant,female fertile,recessive,tumorigenic,wild-type,viable,male fertile,lethal,male,maternal effect,female sterile germline-dependent,lethal - all die before end of embryonic stage,some die during embryonic stage" "ovary,egg chamber,germarium,prothoracic leg & macrochaeta | female" DRSC18835 E 0.225311399 0.597857856 2.412195221 1.737390191 0.077493744 -0.662613765 FBgn0265789 CR44578 - http://flybase.org/reports/FBgn0265789 non_protein_coding_gene - - - CR44578 - CR44578 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046658 anon-38C.51 anon-38C.51 http://flybase.org/reports/FBgn0046658 gene - - - "38C.51, anon-38C.51" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032650 CG7094 - http://flybase.org/reports/FBgn0032650 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966" peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 phagocytosis ; GO:0006909 | inferred from biological aspect of ancestor with PANTHER:PTN000225967 regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein phosphorylation ; GO:0006468 | non-traceable author statement Wnt signaling pathway ; GO:0016055 | inferred from biological aspect of ancestor with PANTHER:PTN000225967 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 cytoplasm ; GO:0005737 | inferred from direct assay CG7094 "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG7094 11-Aug-17 DroID_v2017_08 Drer\csnk1a1 "Scer\YCK3, Scer\YCK1, Scer\HRR25, Scer\YCK2" "Cele\kin-19, Cele\Y111B2A.27, Cele\Y39G8C.2, Cele\K09E4.1" Xtro\csnk1a1 Mmus\Csnk1a1 "Hsap\CSNK1A1, Hsap\CSNK1A1L" viable FBgn0013640 lgm lightminded http://flybase.org/reports/FBgn0013640 - gene - - - lgm - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032187 CG4839 - http://flybase.org/reports/FBgn0032187 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290 cGMP-dependent protein kinase activity ; GO:0004692 | inferred from sequence or structural similarity with for protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with for protein phosphorylation ; GO:0006468 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with for plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with for CG4839 "IPR000595:Cyclic nucleotide-binding domain, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR000961:AGC-kinase, C-terminal, IPR014710:RmlC-like jelly roll fold" CG4839 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-121j17.5, Drer\prkacab, Drer\prkacaa, Drer\LOC556339, Drer\prkg2, Drer\prkx, Drer\prkacbb, Drer\prkg1a, Drer\prkg1b, Drer\prkg1l, Drer\prkacba" "Scer\TPK2, Scer\TPK3, Scer\TPK1" "Cele\egl-4, Cele\pkg-2" "Xtro\prkaca, Xtro\prkx, Xtro\prkacb, Xtro\prkg2" "Mmus\Prkg2, Mmus\Prkx, Mmus\Prkg1, Mmus\Prkaca, Mmus\Prkacb" "Hsap\PRKG1, Hsap\PRKACB, Hsap\PRKACA, Hsap\PRKACG, Hsap\PRKX, Hsap\PRKG2" viable FBgn0005699 l(1)TK102 lethal (1) TK102 http://flybase.org/reports/FBgn0005699 - gene - - - "l102, l(1)TK102" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0265851 CR44640 - http://flybase.org/reports/FBgn0265851 non_protein_coding_gene - - - CR44640 - CR44640 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028393 anon-50ABa anon-50ABa http://flybase.org/reports/FBgn0028393 gene - - - "A, anon-50ABa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031118 RhoGAP19D Rho GTPase activating protein at 19D http://flybase.org/reports/FBgn0031118 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with SGD:S000000957 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN001141612 positive regulation of GTPase activity ; GO:0043547 | inferred from biological aspect of ancestor with PANTHER:PTN001141612 imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype Rho protein signal transduction ; GO:0007266 | inferred from sequence or structural similarity with SGD:S000000957 cellular_component ; GO:0005575 | no biological data available "1412, CG1412, RhoGAP19D" "IPR000198:Rho GTPase-activating protein domain, IPR001478:PDZ domain, IPR008936:Rho GTPase activation protein" CG1412 11-Aug-17 DroID_v2017_08 "Drer\arhgap21b, Drer\arhgap9, Drer\arhgap33, Drer\arhgap23a, Drer\arhgap32a, Drer\LOC556095, Drer\bcr, Drer\arhgap23b, Drer\arhgap32b, Drer\arhgap27l, Drer\arhgap31, Drer\arhgap12a" "Scer\BEM2, Scer\RGD1, Scer\RGA1" "Cele\tag-325, Cele\rrc-1, Cele\pac-1" "Xtro\arhgap21, Xtro\bcr, Xtro\arhgap23" "Mmus\Bcr, Mmus\Arhgap23, Mmus\Arhgap32, Mmus\Arhgap33, Mmus\Arhgap21, Mmus\Arhgap31, Mmus\Arhgap27, Mmus\Arhgap9" "Hsap\ARHGAP27, Hsap\BCR, Hsap\ARHGAP23, Hsap\ARHGAP32, Hsap\ARHGAP21, Hsap\ARHGAP33, Hsap\ARHGAP9, Hsap\ARHGAP31" "partially lethal - majority die,visible" "heart primordium,trichogen cell" DRSC20499 IE 1.553562126 2.010733474 2.561704308 -1.092613116 0.035227209 0.347061147 FBgn0039190 CG5762 - http://flybase.org/reports/FBgn0039190 protein_coding_gene - - - "CG5762, BEST:GH05452, anon-WO0140519.76" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG5762 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0041743 l(2)44Fk lethal (2) 44Fk http://flybase.org/reports/FBgn0041743 gene - - - "l(2)44Fh, l(2)44Fk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266159 CR44865 - http://flybase.org/reports/FBgn0266159 non_protein_coding_gene - - - CR44865 - CR44865 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267794 CR43174 - http://flybase.org/reports/FBgn0267794 non_protein_coding_gene - - - "CR43174, CG43174, CR43173, CG43173, mdcds_28406" - CR43174 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034989 CG3356 - http://flybase.org/reports/FBgn0034989 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:16803 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with Ubc4 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:16803 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000003109 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003109 CG3356 "IPR000048:IQ motif, EF-hand binding site, IPR000569:HECT domain" CG3356 11-Aug-17 DroID_v2017_08 "Drer\ube3b, Drer\ube3c" Scer\HUL5 "Cele\D2085.4, Cele\oxi-1" "Xtro\ube3c, Xtro\ube3b" "Mmus\Ube3b, Mmus\Ube3c" "Hsap\UBE3B, Hsap\UBE3C" viable FBgn0085604 CG41298 - http://flybase.org/reports/FBgn0085604 protein_coding_gene - - - CG41298 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266407 CR45047 - http://flybase.org/reports/FBgn0266407 non_protein_coding_gene - - - CR45047 - CR45047 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028153 l(3)S042622 lethal (3) S042622 http://flybase.org/reports/FBgn0028153 gene - - - "0426/22, l(3)S042622" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266409 CG45049 - http://flybase.org/reports/FBgn0266409 protein_coding_gene - establishment of glial blood-brain barrier ; GO:0060857 | NOT inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004031 septate junction ; GO:0005918 | inferred from sequence or structural similarity with sinu "CG45049, CG17618, CG6982" "IPR004031:PMP-22/EMP/MP20/Claudin superfamily, IPR015664:P53-induced protein" CG45049 11-Aug-17 DroID_v2017_08 "Drer\emp1, Drer\lim2.3, Drer\lim2.5, Drer\lim2.2, Drer\lim2.1, Drer\perp, Drer\tmem47, Drer\lim2.4, Drer\emp2" - Cele\vab-9 "Xtro\emp2, Xtro\cldn18, Xtro\cldn19, Xtro\tmem47, Xtro\lim2, Xtro\perp, Xtro\emp1" "Mmus\Perp, Mmus\Nkg7, Mmus\Emp1, Mmus\Lim2, Mmus\Tmem47, Mmus\Cldnd2, Mmus\Pmp22" "Hsap\EMP2, Hsap\EMP1, Hsap\TMEM202, Hsap\TMEM47, Hsap\NKG7, Hsap\PERP, Hsap\LIM2" FBgn0029795 CG15773 - http://flybase.org/reports/FBgn0029795 protein_coding_gene - - - CG15773 IPR008472:Domain of unknown function DUF753 CG15773 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264003 mir-5613 mir-5613 stem loop http://flybase.org/reports/FBgn0264003 gene - - - "mir-5613, CR43746" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260870 CG42580 - http://flybase.org/reports/FBgn0260870 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42580, HDC19854" - CG42580 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260222 CG42496 - http://flybase.org/reports/FBgn0260222 protein_coding_gene copper ion binding ; GO:0005507 | inferred from sequence or structural similarity with SGD:S000007245 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN001465117 metal ion transport ; GO:0030001 | inferred from sequence or structural similarity with SGD:S000007245 mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from biological aspect of ancestor with PANTHER:PTN001465117 cytosol ; GO:0005829 | inferred from sequence or structural similarity with SGD:S000007245 mitochondrial intermembrane space ; GO:0005758 | inferred from sequence or structural similarity with SGD:S000007245 mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN001465117 "CG42496, Dromel_CG30290_FBtr0071672_cx9c_uORF" IPR010625:CHCH CG42496 11-Aug-17 DroID_v2017_08 Drer\cox19 Scer\COX19 Cele\F45H11.5 Xtro\cox19 Mmus\Cox19 "Hsap\ADAP1, Hsap\COX19" FBgn0003215 rdb reddish brown http://flybase.org/reports/FBgn0003215 - gene - - - rdb - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,visible,viable,male,reduced,recessive,eye color defective" "pigment cell,wing" FBgn0266918 CG32486 - http://flybase.org/reports/FBgn0266918 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001293, InterPro:IPR001841, InterPro:IPR013323" - - "CG32486, CG16745, CG14954, anon-WO0118547.267, l(3)SH095, l(2)SH3 095" "IPR001293:Zinc finger, TRAF-type, IPR001841:Zinc finger, RING-type, IPR008974:TRAF-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG32486 11-Aug-17 DroID_v2017_08 "Drer\siah1, Drer\cyhr1, Drer\siah2l" - - "Xtro\siah2, Xtro\cyhr1, Xtro\siah1" "Mmus\Siah1a, Mmus\Siah1b, Mmus\Siah2, Mmus\Cyhr1, Mmus\Siah3" "Hsap\TRAF3, Hsap\SIAH3, Hsap\SIAH1, Hsap\TRAF4, Hsap\TRAF5, Hsap\SIAH2, Hsap\CYHR1" FBgn0052302 CG32302 - http://flybase.org/reports/FBgn0052302 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG13805, CG32302" IPR002557:Chitin binding domain CG32302 11-Aug-17 DroID_v2017_08 - - "Cele\C39D10.7, Cele\R02F2.4, Cele\Y46H3D.8, Cele\phat-4, Cele\F26D2.13, Cele\F16H6.3, Cele\T05B4.12, Cele\F07C4.11, Cele\F35E8.4, Cele\cpg-2, Cele\T05B4.10, Cele\T05B4.9, Cele\phat-5, Cele\F07C4.10, Cele\F35E8.1, Cele\T05B4.13, Cele\F35E8.6, Cele\cpg-1" - - - "partially lethal - majority die,some die during pupal stage" FBgn0003941 RpL40 Ribosomal protein L40 http://flybase.org/reports/FBgn0003941 FBgn0061410 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001975 protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000003962 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001975 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000003962 cytoplasmic translation ; GO:0002181 | traceable author statement ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity translation ; GO:0006412 | traceable author statement cellular protein modification process ; GO:0006464 | inferred from sequence or structural similarity cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | inferred from direct assay "Ub52, CEP52, DUb52, Ubi-f52, Ubi-f, Dub52, CG2960, BcDNA:RE10554, RpL40, Ubiq, Rpl40, L40, RPL40" "IPR000626:Ubiquitin domain, IPR001975:Ribosomal protein L40e, IPR019954:Ubiquitin conserved site, IPR019956:Ubiquitin, IPR029071:Ubiquitin-related domain" CG2960 11-Aug-17 DroID_v2017_08 "Drer\ubc, Drer\ubb, Drer\nedd8l, Drer\uba52, Drer\kxd1, Drer\si:ch211-202a12.4, Drer\nedd8" "Scer\RPL40B, Scer\RPL40A" "Cele\F52C6.3, Cele\ubq-2, Cele\ned-8, Cele\kxd-1, Cele\ubl-1, Cele\F52C6.2" "Xtro\rps27a, Xtro\kxd1, Xtro\uba52, Xtro\nedd8, Xtro\ubc" "Mmus\Ubb, Mmus\Nedd8, Mmus\Isg15, Mmus\Ubc, Mmus\Rps27a, Mmus\Ubd, Mmus\Uba52" "Hsap\RPS27A, Hsap\NEDD8, Hsap\UBA52, Hsap\UBD, Hsap\UBC, Hsap\UBB, Hsap\ISG15" " larval stage | third instar , embryonic stage -- adult stage , oogenesis stage && adult stage | female " " embryonic/larval hindgut

, embryonic/larval fat body

, Malpighian tubule

, ovary

, imaginal disc

, embryonic/larval salivary gland

" "lethal,partially lethal - majority die,visible" mesothoracic tergum DRSC00782 IEK -1.286597952 -2.426221723 0.371928196 -4.61537324 1.156605366 1.600366119 FBgn0065785 l(2)SH0436 lethal (2) SH0436 http://flybase.org/reports/FBgn0065785 gene - - - "l(2)SH0436, l(2)SH2 0436" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069243 driceless driceless http://flybase.org/reports/FBgn0069243 gene - spermatid nucleus differentiation ; GO:0007289 | inferred from mutant phenotype - driceless - - 11-Aug-17 DroID_v2017_08 - - - - - - spermatid FBgn0004840 Zhr Zygotic hybrid rescue http://flybase.org/reports/FBgn0004840 - gene - - - "zhr, Zhr, Zhr[ts]" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065336 l(2)SH1851 lethal (2) SH1851 http://flybase.org/reports/FBgn0065336 gene - - - "l(2)SH1851, l(2)SH2 1851" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058397 CG40397 - http://flybase.org/reports/FBgn0058397 protein_coding_gene - - - CG40397 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035842 CG7504 - http://flybase.org/reports/FBgn0035842 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay CG7504 "IPR000253:Forkhead-associated (FHA) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR008984:SMAD/FHA domain" CG7504 11-Aug-17 DroID_v2017_08 "Drer\znfx1, Drer\setx" "Scer\ECM32, Scer\SEN1" "Cele\ZK1067.2, Cele\eri-7" Xtro\setx "Mmus\Znfx1, Mmus\Setx" "Hsap\SETX, Hsap\ZNFX1" "viable,female sterile,female fertile" FBgn0027162 l(2)KC-D l(2)Karp and Cherbas D http://flybase.org/reports/FBgn0027162 - gene - - - "D, l(2)KC-D" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037934 CG6830 - http://flybase.org/reports/FBgn0037934 protein_coding_gene - - - CG6830 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG6830 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - Cele\F20D6.5 - - - "viable,fertile" FBgn0043046 cfo centrosome fall off http://flybase.org/reports/FBgn0043046 gene - maintenance of centrosome location ; GO:0051661 | inferred from mutant phenotype regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | inferred from mutant phenotype regulation of exit from mitosis ; GO:0007096 | inferred from mutant phenotype - cfo - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "mitotic cell cycle | embryonic stage,spindle,centrosome" FBgn0263456 nwk nervous wreck http://flybase.org/reports/FBgn0263456 protein_coding_gene phospholipid binding ; GO:0005543 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with Snx16 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from genetic interaction with Snx16 regulation of actin filament polymerization ; GO:0030833 | inferred from direct assay regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype receptor recycling ; GO:0001881 | inferred from genetic interaction with Snx16 regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay "CG4684, CG43479, nwk, Nwk, NWK, CG4641" "IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR001060:FCH domain, IPR001452:SH3 domain, IPR031160:F-BAR domain" CG43479 11-Aug-17 DroID_v2017_08 "Drer\LOC100537850, Drer\LOC100536453, Drer\si:ch211-176g13.8" Scer\BZZ1 Cele\C26C6.8 "Xtro\fchsd1, Xtro\fchsd2" "Mmus\Fchsd1, Mmus\Fchsd2" "Hsap\FCHSD2, Hsap\FCHSD1" FBgn0267623 CR45961 - http://flybase.org/reports/FBgn0267623 non_protein_coding_gene - - - CR45961 - CR45961 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266801 CG45263 - http://flybase.org/reports/FBgn0266801 protein_coding_gene - - - "CG31369/CG31462, CG43462, CG45263, 43462, CG31369, CG31264, CG11733, CG11731, CG11730, BcDNA:GH22170, BcDNA:AT05815, anon-EST:Posey178, CT32186, GH22170, GS3056, MRE1, CG42285, CG11718, CG42286, CG11729, CG31462" "IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2, IPR013162:CD80-like, immunoglobulin C2-set, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG45263 11-Aug-17 DroID_v2017_08 "Drer\LOC799279, Drer\kirrelb, Drer\il1rapl1b, Drer\kirrel3l, Drer\il1rapl2, Drer\kirrel3a, Drer\kirrela, Drer\il1rapl1a" - "Cele\igcm-1, Cele\syg-1, Cele\igcm-3" "Xtro\kirrel2, Xtro\il1r2" "Mmus\Il1rl1, Mmus\Il1rapl2, Mmus\Kirrel2, Mmus\Il1r1, Mmus\Il18r1, Mmus\Il1rapl1, Mmus\Sigirr, Mmus\Il1rl2, Mmus\Kirrel, Mmus\Kirrel3, Mmus\Il1r2, Mmus\Il18rap, Mmus\Il1rap" "Hsap\IL1RAPL1, Hsap\IL18R1, Hsap\IL1R1, Hsap\IL1RAP, Hsap\IL1RAPL2, Hsap\KIRREL, Hsap\IL1RL1, Hsap\IL18RAP, Hsap\IL1RL2, Hsap\KIRREL3, Hsap\SIGIRR, Hsap\IL1R2, Hsap\KIRREL2" DRSC14363 I -0.740550596 -1.997640744 -0.904398763 0.641417916 -0.020711278 -0.402363167 FBgn0032202 REPTOR-BP REPTOR-binding partner http://flybase.org/reports/FBgn0032202 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR004827 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827 protein dimerization activity ; GO:0046983 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with REPTOR" "regulation of multicellular organismal metabolic process ; GO:0044246 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype TORC1 signaling ; GO:0038202 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "BcDNA:RH73910, REPTOR-BP, CG18619, DM20" IPR004827:Basic-leucine zipper domain CG18619 11-Aug-17 DroID_v2017_08 Drer\crebl2 - - Xtro\crebl2 Mmus\Crebl2 Hsap\CREBL2 "viable,fertile" FBgn0037161 CG14460 - http://flybase.org/reports/FBgn0037161 protein_coding_gene - - - CG14460 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC11720 I 0.937840866 2.351672302 0.933501775 1.062319185 0.793448937 -0.923223044 FBgn0243502 l(2)CB02900 - http://flybase.org/reports/FBgn0243502 gene - - - l(2)CB02900 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002392 l(3)93Di lethal (3) 93Di http://flybase.org/reports/FBgn0002392 - gene - - - "er12, l(3)er12, l(3)93Di" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0065155 l(3)SH052 lethal (3) SH052 http://flybase.org/reports/FBgn0065155 gene - - - "l(3)SH052, l(2)SH3 052" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022051 l(2)k08222 lethal (2) k08222 http://flybase.org/reports/FBgn0022051 - gene - - - l(2)k08222 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001772 l(1)M46 lethal (1) M46 http://flybase.org/reports/FBgn0001772 - gene - - - l(1)M46 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0060516 l(3)S103707b lethal (3) S103707b http://flybase.org/reports/FBgn0060516 gene - - - "1037/07, l(3)S103707b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0034379 CG15073 - http://flybase.org/reports/FBgn0034379 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG15073 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG15073 11-Aug-17 DroID_v2017_08 "Drer\prdm10, Drer\si:dkey-30k6.5, Drer\prdm5, Drer\zgc:153116" - "Cele\row-1, Cele\ztf-23, Cele\sdz-12, Cele\eor-1" "Xtro\prdm5, Xtro\znf652" "Mmus\Zfy1, Mmus\Zfy2, Mmus\Zim1, Mmus\Prdm10" "Hsap\ZNF652, Hsap\PRDM10, Hsap\PRDM5" viable FBgn0011961 tRNA:Arg-ACG-1-8 transfer RNA:Arginine-ACG 1-8 http://flybase.org/reports/FBgn0011961 "FBgn0003758, FBgn0011947, FBgn0051582, FBgn0060095" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "tRNA[arg], tRNA[Arg][[2]], AE002708.trna64-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002708-c, CR31582, tRNA:arg2:84Fc, chr3R.trna70-ArgACG, tRNA-Arg-ACG-1-8, tRNA:Arg-ACG-1-8, tRNA:R2:84Fc, CGU" - CR31582 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035568 CG18418 - http://flybase.org/reports/FBgn0035568 protein_coding_gene oxoglutarate:malate antiporter activity ; GO:0015367 | inferred from sequence or structural similarity with UniProtKB:Q02978 oxoglutarate:malate antiporter activity ; GO:0015367 | inferred from biological aspect of ancestor with PANTHER:PTN001942042 malate transport ; GO:0015743 | inferred from sequence or structural similarity with UniProtKB:Q02978 mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:Q02978 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 alpha-ketoglutarate transport ; GO:0015742 | inferred from sequence or structural similarity with UniProtKB:Q02978 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q02978 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001942042 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "anon-WO0140519.190, CG18418" "IPR002030:Mitochondrial brown fat uncoupling protein, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG18418 11-Aug-17 DroID_v2017_08 "Drer\slc25a14, Drer\slc25a10, Drer\slc25a11, Drer\ucp2, Drer\si:ch1073-100f3.2, Drer\mrpl12" Scer\DIC1 "Cele\misc-1, Cele\slc-25A10, Cele\ucp-4, Cele\mrpl-12" "Xtro\ucp1, Xtro\slc25a27, Xtro\rangrf, Xtro\slc25a30, Xtro\slc25a10, Xtro\ucp2" "Mmus\Slc25a27, Mmus\Slc25a10, Mmus\Ucp1, Mmus\Slc25a11, Mmus\Slc25a14, Mmus\Slc25a30, Mmus\Ucp3, Mmus\Ucp2, Mmus\Mrpl12" "Hsap\SLC25A27, Hsap\UCP3, Hsap\SLC25A10, Hsap\SLC25A14, Hsap\SLC25A11, Hsap\UCP2, Hsap\UCP1, Hsap\MRPL12, Hsap\SLC25A30" viable DRSC08535 K -0.216374123 1.203140915 -0.306216913 0.261852222 1.710548532 -0.231077627 FBgn0050180 CG30180 - http://flybase.org/reports/FBgn0050180 protein_coding_gene - - - CG30180 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036759 CG5577 - http://flybase.org/reports/FBgn0036759 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000002395 alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with SGD:S000002395 phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002395 dephosphorylation ; GO:0016311 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002395 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002395 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000445812 "CG5577, 20151379" "IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG5577 11-Aug-17 DroID_v2017_08 "Drer\pgp, Drer\pdxp" Scer\PHO13 "Cele\K02D10.1, Cele\C45E5.1, Cele\K09H11.7, Cele\F44E7.2, Cele\C53A3.2" - "Mmus\Pgp, Mmus\Pdxp" "Hsap\PDXP, Hsap\HDHD2, Hsap\PGP" "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0035374 mRpS35 mitochondrial ribosomal protein S35 http://flybase.org/reports/FBgn0035374 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y2Q9 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y2Q9 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y2Q9 "MRP-S28, CG2101, mRpS35" "IPR019349:Ribosomal protein S24/S35, mitochondrial, conserved domain" CG2101 11-Aug-17 DroID_v2017_08 Drer\mrps35 Scer\RSM24 Cele\mrps-35 Xtro\mrps35 Mmus\Mrps35 Hsap\MRPS35 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC08551 E -0.286116412 -0.102567758 -1.74965249 0.187934251 0.188002677 0.814522601 FBgn0020316 anon-92CDa anon-92CDa http://flybase.org/reports/FBgn0020316 - gene - - - "512, anon-92CDa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058057 CG40057 - http://flybase.org/reports/FBgn0058057 protein_coding_gene - - - CG40057 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035317 Oseg2 Outer segment 2 http://flybase.org/reports/FBgn0035317 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with NCBI_gi:1086678 cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with MGI:MGI:2682064 cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with UniProtKB:Q6VH22 intraciliary transport ; GO:0042073 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:2682064 axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000404360 intraciliary transport particle B ; GO:0030992 | inferred from biological aspect of ancestor with PANTHER:PTN000404408 cilium ; GO:0005929 | inferred from sequence or structural similarity with UniProtKB:Q6VH22 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN000404360 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with NCBI_gi:1086678 intraciliary transport particle ; GO:0030990 | inferred from sequence or structural similarity with UniProtKB:Q5DM57 non-motile cilium ; GO:0097730 | inferred from direct assay intraciliary transport particle ; GO:0030990 | inferred from sequence or structural similarity with MGI:MGI:2682064 "IFT172, Oseg2, OSEG2, CG13809, OSEG, OSM-1, oseg2, osm-1" "IPR011990:Tetratricopeptide-like helical domain, IPR011042:Six-bladed beta-propeller, TolB-like, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG13809 11-Aug-17 DroID_v2017_08 Drer\ift172 - Cele\osm-1 Xtro\ift172 Mmus\Ift172 Hsap\IFT172 "neurophysiology defective,viable" "trichogen cell,mechanosensory neuron,cilium & cell" FBgn0065818 l(2)SH0376 lethal (2) SH0376 http://flybase.org/reports/FBgn0065818 gene - - - "l(2)SH0376, l(2)SH2 0376" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267279 CR45715 - http://flybase.org/reports/FBgn0267279 non_protein_coding_gene - - - CR45715 - CR45715 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052119 CG32119 - http://flybase.org/reports/FBgn0052119 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs34d09, BcDNA:AT05691, CG32119" - CG32119 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259682 Jabba Jabba http://flybase.org/reports/FBgn0259682 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available lipid particle ; GO:0005811 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "141242_at, anon-WO0118547.167, CG1509, BP1008, CG15092, CG34020, CG42351, Jabba" IPR032150:Protein of unknown function DUF4820 CG42351 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260073 2L3569 - http://flybase.org/reports/FBgn0260073 gene - - - 2L3569 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0065042 2SrRNA 2SrRNA http://flybase.org/reports/FBgn0065042 rRNA_gene - - - "2S rRNA, 2SRNA, 2SrRNA, 2S" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035743 CG15829 - http://flybase.org/reports/FBgn0035743 protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 - - CG15829 "IPR000582:Acyl-CoA-binding protein, ACBP, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR022408:Acyl-CoA-binding protein, ACBP, conserved site" CG15829 11-Aug-17 DroID_v2017_08 "Drer\acbd7, Drer\dbi, Drer\acbd4, Drer\zgc:92030, Drer\acbd6, Drer\mettl23, Drer\LOC103909942, Drer\acbd5b" Scer\ACB1 "Cele\acbp-1, Cele\acbp-6, Cele\maa-1, Cele\acbp-5, Cele\acbp-3, Cele\acbp-4" "Xtro\eci2, Xtro\mettl23, Xtro\acbd6, Xtro\acbd5, Xtro\acbd7" "Mmus\Acbd7, Mmus\Eci2, Mmus\Acbd5, Mmus\Acbd6, Mmus\Dbi, Mmus\Dbil5, Mmus\Mettl23, Mmus\Acbd4" "Hsap\ACBD7, Hsap\ECI2, Hsap\ACBD4, Hsap\ACBD6, Hsap\ACBD5, Hsap\METTL23, Hsap\DBI" FBgn0053531 Ddr Discoidin domain receptor http://flybase.org/reports/FBgn0053531 protein_coding_gene "protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245 protein phosphorylation ; GO:0006468 | non-traceable author statement" - "CG9488, CG9490, CG11573, CT33540, DDR, CG13985, CG33531, Ddr" "IPR011009:Protein kinase-like domain, IPR000719:Protein kinase domain, IPR008979:Galactose-binding domain-like, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR000421:Coagulation factor 5/8 C-terminal domain" CG33531 11-Aug-17 DroID_v2017_08 "Drer\ddr1, Drer\ddr2a, Drer\ddr2l, Drer\ddr2b" - "Cele\ddr-2, Cele\ddr-1" "Xtro\ddr1, Xtro\ddr2" "Mmus\Ddr2, Mmus\F8, Mmus\Ddr1" "Hsap\DDR1, Hsap\DDR2" "viable,visible" "trichogen cell,mesothoracic tergum" DRSC02150 K 0.922384953 -0.493883575 -0.068283599 -0.999411632 0.899173395 1.890413966 FBgn0039125 Ndc1 Nuclear division cycle 1 http://flybase.org/reports/FBgn0039125 protein_coding_gene structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000327778 structural constituent of nuclear pore ; GO:0017056 | inferred from sequence or structural similarity with HGNC:25525 nuclear pore organization ; GO:0006999 | inferred from biological aspect of ancestor with PANTHER:PTN000327778 nuclear pore complex assembly ; GO:0051292 | inferred from sequence or structural similarity with HGNC:25525 neurogenesis ; GO:0022008 | inferred from mutant phenotype nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with HGNC:25525 nuclear pore transmembrane ring ; GO:0070762 | inferred from biological aspect of ancestor with PANTHER:PTN000327778 endomembrane system ; GO:0012505 | inferred from direct assay "CG5857, Ndc1, NDC1" IPR019049:Nucleoporin protein Ndc1-Nup CG5857 11-Aug-17 DroID_v2017_08 Drer\ndc1 Scer\NDC1 Cele\npp-22 Xtro\ndc1 Mmus\Ndc1 Hsap\NDC1 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,supernumerary,trichogen cell,tormogen cell" FBgn0038490 CG5285 - http://flybase.org/reports/FBgn0038490 protein_coding_gene oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity ; GO:0000703 | inferred from biological aspect of ancestor with PANTHER:PTN000996960 uracil DNA N-glycosylase activity ; GO:0004844 | inferred from biological aspect of ancestor with PANTHER:PTN000996960 - nuclear lumen ; GO:0031981 | inferred from biological aspect of ancestor with PANTHER:PTN000996960 CG5285 IPR005122:Uracil-DNA glycosylase-like CG5285 11-Aug-17 DroID_v2017_08 Drer\smug1 - - Xtro\smug1 Mmus\Smug1 Hsap\SMUG1 "viable,fertile" FBgn0027098 1688-2E 1688-2E http://flybase.org/reports/FBgn0027098 - repeat_region - - - 1688-2E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001820 l(1)sd lethal (1) scheiben enlarged http://flybase.org/reports/FBgn0001820 - gene - - - l(1)sd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "imaginal disc,embryonic/larval salivary gland" FBgn0037724 Fst Frost http://flybase.org/reports/FBgn0037724 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to cold ; GO:0009409 | inferred from mutant phenotype cold acclimation ; GO:0009631 | inferred from expression pattern response to cold ; GO:0009409 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG9434, frost, Fst" - CG9434 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage,cold stress response defective,female limited" FBgn0031529 CG9662 - http://flybase.org/reports/FBgn0031529 protein_coding_gene - - oligosaccharyltransferase complex ; GO:0008250 | inferred from biological aspect of ancestor with PANTHER:PTN000322702 "BcDNA:AT03617, CG9662" "IPR021149:Oligosaccharyl transferase complex, subunit OST3/OST6" CG9662 11-Aug-17 DroID_v2017_08 Drer\ostc - - Xtro\ostc Mmus\Ostc Hsap\OSTC "viable,fertile" FBgn0050366 swif swift-tuttle http://flybase.org/reports/FBgn0050366 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG2149, swif, CG30366" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG30366 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034137 CG4945 - http://flybase.org/reports/FBgn0034137 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000684417" peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000684417 peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000684417 mesoderm development ; GO:0007498 | non-traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "PKN, CT15864, CG4945" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG4945 11-Aug-17 DroID_v2017_08 "Drer\sbk3, Drer\unm_sa1261, Drer\si:dkey-8e10.3, Drer\si:ch211-183d21.3, Drer\bsk146, Drer\mark2b, Drer\si:ch211-171h4.3, Drer\LOC791840" "Scer\CHK1, Scer\KKQ8, Scer\RTK1, Scer\PTK2, Scer\HAL5, Scer\SAT4, Scer\PRR2, Scer\PTK1" "Cele\Y39G8B.5, Cele\C01C4.3, Cele\ikke-1" "Xtro\sbk1, Xtro\LOC100135243, Xtro\LOC100496267, Xtro\sbk2, Xtro\LOC100495913" "Mmus\Sbk2, Mmus\Sbk1, Mmus\Sbk3" "Hsap\SBK1, Hsap\SBK2, Hsap\SBK3" "viable,fertile" FBgn0053481 dpr7 defective proboscis extension response 7 http://flybase.org/reports/FBgn0053481 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG33481, Dpr-7, dpr7, Dpr7" "IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype, IPR003598:Immunoglobulin subtype 2" CG33481 11-Aug-17 DroID_v2017_08 "Drer\LOC101885444, Drer\si:ch211-163c2.2, Drer\si:dkey-65b12.12, Drer\LOC101885725, Drer\LOC100333196, Drer\si:ch211-264f5.6" - "Cele\zig-1, Cele\zig-8" Xtro\obsl1 Mmus\Amica1 - viable FBgn0021919 l(2)k11311 lethal (2) k11311 http://flybase.net/reports/FBgn0021919.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0264887 CR44078 - http://flybase.org/reports/FBgn0264887 non_protein_coding_gene - - - CR44078 - CR44078 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267945 CR46225 - http://flybase.org/reports/FBgn0267945 non_protein_coding_gene - - - "CR46225, lincRNA.719" - CR46225 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013317 Pcp19 Pupal-cuticle-protein-19kD http://flybase.org/reports/FBgn0013317 - gene - - - Pcp19 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000671 fliE flightless E http://flybase.org/reports/FBgn0000671 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fliE - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,heat sensitive" FBgn0030742 CG9919 - http://flybase.org/reports/FBgn0030742 protein_coding_gene - - - CG9919 - CG9919 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267288 CR45724 - http://flybase.org/reports/FBgn0267288 non_protein_coding_gene - - - CR45724 - CR45724 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267753 CR46084 - http://flybase.org/reports/FBgn0267753 non_protein_coding_gene - - - CR46084 - CR46084 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022154 l(2)k05816 lethal (2) k05816 http://flybase.org/reports/FBgn0022154 - gene - - - l(2)k05816 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260771 Larp7 La related protein 7 http://flybase.org/reports/FBgn0260771 protein_coding_gene 7SK snRNA binding ; GO:0097322 | inferred from direct assay RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR002344 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR002344 intracellular ribonucleoprotein complex ; GO:0030529 | inferred from electronic annotation with InterPro:IPR002344 "CG12058, Larp7, dLARP7, CG42569" "IPR002344:Lupus La protein, IPR014886:La protein, RNA-binding domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR006630:RNA-binding protein Lupus La, IPR000504:RNA recognition motif domain" CG42569 11-Aug-17 DroID_v2017_08 "Drer\ssb, Drer\larp7" Scer\LHP1 Cele\C44E4.4 Xtro\larp7 "Mmus\Larp7, Mmus\Ssb, Mmus\Gm12666" "Hsap\LARP7, Hsap\SSB" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" DRSC18798 I -0.34992358 -1.555242589 0.053018091 -0.851386699 0.032746168 0.04257402 FBgn0011072 l(1)Q25 lethal (1) Q25 http://flybase.org/reports/FBgn0011072 FBgn0010210 gene - - - l(1)Q25 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028203 l(3)S015601b lethal (3) S015601b http://flybase.org/reports/FBgn0028203 gene - - - "0156/01, l(3)S015601, l(3)S015601b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034428 CG18606 - http://flybase.org/reports/FBgn0034428 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 CG18606 IPR016181:Acyl-CoA N-acyltransferase CG18606 11-Aug-17 DroID_v2017_08 - - "Cele\T10B5.4, Cele\M7.8, Cele\R05H10.7, Cele\M7.12, Cele\anat-1" - - - viable FBgn0036335 mRpL20 mitochondrial ribosomal protein L20 http://flybase.org/reports/FBgn0036335 protein_coding_gene rRNA binding ; GO:0019843 | inferred from electronic annotation with InterPro:IPR005813 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049644 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049644 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049644 "CG11258, L20, anon-WO0118547.265, mRpL20" IPR005813:Ribosomal protein L20 CG11258 11-Aug-17 DroID_v2017_08 Drer\mrpl20 - Cele\mrpl-20 Xtro\mrpl20 Mmus\Mrpl20 Hsap\MRPL20 "viable,fertile,visible" trichogen cell FBgn0060467 l(3)S113204a lethal (3) S113204a http://flybase.org/reports/FBgn0060467 gene - - - "1132/04, l(3)S113204a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0037975 CG3397 - http://flybase.org/reports/FBgn0037975 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020471 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR020471 - CG3397 "IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG3397 11-Aug-17 DroID_v2017_08 Drer\srm Scer\ARA2 "Cele\mec-14, Cele\C35D10.6" Xtro\srm "Mmus\Kcnab1, Mmus\Srm" "Hsap\KCNAB1, Hsap\SRM" FBgn0020330 anon-6C5 anon-6C5 http://flybase.org/reports/FBgn0020330 - gene - - - "6C5, anon-6C5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035232 CG12099 - http://flybase.org/reports/FBgn0035232 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10055 zinc ion binding ; GO:0008270 | inferred from sequence model protein autoubiquitination ; GO:0051865 | inferred from sequence or structural similarity with HGNC:10055 cellular_component ; GO:0005575 | no biological data available CG12099 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR018957:Zinc finger, C3HC4 RING-type" CG12099 11-Aug-17 DroID_v2017_08 "Drer\rnf170, Drer\rnf10, Drer\si:dkey-183n20.15" "Scer\SLX8, Scer\MAG2" Cele\Y38F1A.2 "Xtro\rnf170, Xtro\rnf10" "Mmus\Rnf10, Mmus\Rnf170" "Hsap\RNF170, Hsap\RNF10" "viable,fertile" FBgn0016892 l(3)64Cb lethal (3) 64Cb http://flybase.org/reports/FBgn0016892 - gene - - - l(3)64Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060471 l(3)S112202b lethal (3) S112202b http://flybase.org/reports/FBgn0060471 gene - - - "1122/02, l(3)S112202b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085483 CG34454 - http://flybase.org/reports/FBgn0085483 protein_coding_gene - - extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Kaz1-ORFB mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with Kaz1-ORFB "CG34454, CG34018" IPR002350:Kazal domain CG34454 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-77g12.4, Drer\si:dkey-203a12.4, Drer\spink4, Drer\si:dkey-203a12.3, Drer\si:dkey-203a12.6" - - - "Mmus\Spink7, Mmus\Spink11, Mmus\Spink2, Mmus\Spink4, Mmus\Spinkl, Mmus\Spink14" "Hsap\SPINK4, Hsap\SPINK14, Hsap\SPINK7, Hsap\SPINK9" FBgn0260102 2L0196 - http://flybase.org/reports/FBgn0260102 gene - - - 2L0196 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval dorsal trunk,somatic clone" FBgn0070043 3R-259-18 3R-259-18 http://flybase.org/reports/FBgn0070043 gene molecular_function ; GO:0003674 | no biological data available oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-259-18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "dorsal appendage,germline clone,non-rescuable maternal effect,egg,maternal effect" FBgn0020816 l(3)Fox lethal (3) Fox http://flybase.org/reports/FBgn0020816 - gene - - - l(3)Fox - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043891 l(3)113 lethal (3) 113 http://flybase.org/reports/FBgn0043891 gene - - - l(3)113 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058173 CG40173 - http://flybase.org/reports/FBgn0058173 protein_coding_gene - - - CG40173 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016004 l(3)63Ec lethal (3) 63Ec http://flybase.org/reports/FBgn0016004 - gene - - - "l63Ec, l(3)SH2, l(3)63Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013241 E(var)222 E(var)222 http://flybase.org/reports/FBgn0013241 - gene - - - E(var)222 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0060967 l(3)S030704b lethal (3) S030704b http://flybase.org/reports/FBgn0060967 gene - - - "0307/04, l(3)S030704b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034840 CG3124 - http://flybase.org/reports/FBgn0034840 protein_coding_gene - - - "anon-WO0140519.230, CG3124" - CG3124 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060884 l(3)S044805 lethal (3) S044805 http://flybase.org/reports/FBgn0060884 gene - - - "0448/05, l(3)S044805" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053723 CG33723 - http://flybase.org/reports/FBgn0053723 protein_coding_gene - - - CG33723 IPR010512:Protein of unknown function DUF1091 CG33723 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0035449 CG14971 - http://flybase.org/reports/FBgn0035449 protein_coding_gene - - Golgi trans cisterna ; GO:0000138 | inferred from direct assay CG14971 IPR004853:Sugar phosphate transporter domain CG14971 11-Aug-17 DroID_v2017_08 "Drer\LOC101884357, Drer\slc35c2" "Scer\YJL193W, Scer\YMD8" Cele\Y47G6A.7 Xtro\slc35c2 Mmus\Slc35c2 Hsap\SLC35C2 "viable,fertile" FBgn0028169 l(3)S027607 lethal (3) S027607 http://flybase.org/reports/FBgn0028169 gene - - - "0276/07, l(3)S027607" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0036143 CG14142 - http://flybase.org/reports/FBgn0036143 protein_coding_gene - - - CG14142 IPR025257:Domain of unknown function DUF4205 CG14142 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-30h22.11, Drer\aqp3b, Drer\aqp8a.1, Drer\aqp4, Drer\aqp1a.1, Drer\fam188a, Drer\aqp3a" "Scer\YLL053C, Scer\YFL054C, Scer\AQY1" "Cele\aqp-7, Cele\aqp-6, Cele\aqp-2, Cele\aqp-8, Cele\aqp-4" "Xtro\aqp2, Xtro\fam188b, Xtro\aqp8, Xtro\fam188b2, Xtro\LOC100489792, Xtro\fam188a" "Mmus\Fam188a, Mmus\Aqp3, Mmus\Aqp7, Mmus\Aqp2, Mmus\Fam188b, Mmus\Aqp8, Mmus\Aqp4, Mmus\Aqp1" "Hsap\FAM188B2, Hsap\AQP8, Hsap\AQP1, Hsap\AQP3, Hsap\INMT, Hsap\FAM188B, Hsap\AQP2, Hsap\FAM188A, Hsap\AQP7, Hsap\AQP9" viable DRSC10145 E -0.325105954 -0.253453478 -1.680122873 -0.265959501 -0.324411199 -0.671800505 FBgn0024724 Su(var)38D Su(var)38D http://flybase.org/reports/FBgn0024724 - gene - - - Su(var)38D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001459 l(1)7Dm lethal (1) 7Dm http://flybase.org/reports/FBgn0001459 - gene - - - "RA5, l(1)7Dm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,germline clone,maternal effect" FBgn0035477 CG14982 - http://flybase.org/reports/FBgn0035477 protein_coding_gene - - - CG14982 "IPR025741:Centrosome-associated, FAM110, C-terminal domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG14982 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005075 fs(2)OW216 female sterile (2) OW216 http://flybase.org/reports/FBgn0005075 - gene - - - fs(2)OW216 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003427 slm10A slim at 10A http://flybase.org/reports/FBgn0003427 - gene - - - "slm10A, slm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,small body,partially lethal - majority die,viable,fertile,visible,recessive" "abdomen,wing,adult abdomen" FBgn0033730 Cpr49Ag Cuticular protein 49Ag http://flybase.org/reports/FBgn0033730 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr49Ag, CG8511, DmelCpr49Ag" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8511 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0263444 CR43467 - http://flybase.org/reports/FBgn0263444 non_protein_coding_gene - - - CR43467 - CR43467 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041785 S(Sev-CycE)D17 S(Sev-CycE)D17 http://flybase.org/reports/FBgn0041785 gene - - - S(Sev-CycE)D17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031087 CG12656 - http://flybase.org/reports/FBgn0031087 protein_coding_gene - - - "BcDNA:RH47776, BcDNA:RE41492, CG12656" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263916 Ent2 Equilibrative nucleoside transporter 2 http://flybase.org/reports/FBgn0263916 protein_coding_gene nucleoside transmembrane transporter activity ; GO:0005337 | inferred from sequence or structural similarity with HGNC:11003 inferred from sequence or structural similarity with HGNC:11004 associative learning ; GO:0008306 | inferred from mutant phenotype nucleoside transport ; GO:0015858 | inferred from sequence or structural similarity with HGNC:11003 inferred from sequence or structural similarity with HGNC:11004 negative regulation of calcium ion import ; GO:0090281 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002259 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay "Ent2, P124, CG11045, DmENT2, LD04971, CG31911, BEST:LD04971, ent2, DmEnt2" "IPR020846:Major facilitator superfamily domain, IPR002259:Equilibrative nucleoside transporter" CG31911 11-Aug-17 DroID_v2017_08 "Drer\LOC100334018, Drer\slc29a2, Drer\slc29a1b, Drer\slc29a3, Drer\slc29a4, Drer\slc29a1a, Drer\si:ch211-160d14.6" Scer\FUN26 "Cele\ent-7, Cele\ent-6, Cele\ent-2, Cele\ent-4, Cele\ent-1, Cele\ent-5, Cele\ent-3" Xtro\slc29a2 "Mmus\Slc29a4, Mmus\Slc29a3, Mmus\Slc29a2, Mmus\Slc29a1" "Hsap\SLC29A3, Hsap\SLC29A4, Hsap\SLC29A1, Hsap\SLC29A2" FBgn0058159 CG40159 - http://flybase.org/reports/FBgn0058159 protein_coding_gene - - - CG40159 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050369 CG30369 - http://flybase.org/reports/FBgn0050369 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs06h11, CG30369" - CG30369 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0037652 CG11980 - http://flybase.org/reports/FBgn0037652 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.327, CG11980" IPR003226:Metal-dependent protein hydrolase CG11980 11-Aug-17 DroID_v2017_08 Drer\myg1 Scer\YER156C Cele\C27H6.8 Xtro\c12orf10 Mmus\Myg1 Hsap\C12orf10 viable FBgn0053998 CG33998 - http://flybase.org/reports/FBgn0053998 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1058, CG33998" IPR031734:Transcription activator MBF2 CG33998 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061032 l(3)S024106 lethal (3) S024106 http://flybase.org/reports/FBgn0061032 gene - - - "0241/06, l(3)S024106" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019871 l(3)96Ac lethal (3) 96Ac http://flybase.org/reports/FBgn0019871 - gene - - - "291.6, anon-96Ac, l(3)96Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028970 betaggt-II beta subunit of type II geranylgeranyl transferase http://flybase.org/reports/FBgn0028970 protein_coding_gene Rab geranylgeranyltransferase activity ; GO:0004663 | contributes_to inferred from direct assay protein geranylgeranylation ; GO:0018344 | inferred from biological aspect of ancestor with PANTHER:PTN000206738 Rab-protein geranylgeranyltransferase complex ; GO:0005968 | inferred from direct assay "RabGGTbeta, betaggt II, CG18627, betaggt, GGT-II beta, betaggt-II" "IPR001330:PFTB repeat, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR026873:Geranylgeranyl transferase type-2 subunit beta" CG18627 11-Aug-17 DroID_v2017_08 Drer\rabggtb "Scer\BET2, Scer\CDC43" Cele\ggtb-1 Xtro\rabggtb Mmus\Rabggtb Hsap\RABGGTB "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0024885 l(2)02438 lethal (2) 02438 http://flybase.org/reports/FBgn0024885 - gene - - - "2438, l(2)02438" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002328 l(3)86Fg lethal (3) 86Fg http://flybase.org/reports/FBgn0002328 - gene - - - "549/7, 0549/07, ck7, l(3)ck7, l(3)86Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0046222 Wdr33 WD repeat domain 33 http://flybase.org/reports/FBgn0046222 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype mRNA cleavage ; GO:0006379 | inferred from biological aspect of ancestor with PANTHER:PTN000519834 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000519834 "CG1109, BcDNA:LD24014, WDR33, Wdr33" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR020472:G-protein beta WD-40 repeat" CG1109 11-Aug-17 DroID_v2017_08 Drer\wdr33 Scer\PFS2 Cele\pfs-2 Xtro\wdr33 Mmus\Wdr33 Hsap\WDR33 lethal DRSC12162 I 2.078679876 2.600321646 0.590784156 -1.081009484 -0.890575441 0.183609383 FBgn0004396 CrebA Cyclic-AMP response element binding protein A http://flybase.org/reports/FBgn0004396 "FBgn0004848, FBgn0010804, FBgn0041115, FBgn0062892" protein_coding_gene "enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity DNA binding ; GO:0003677 | inferred from direct assay" "salivary gland development ; GO:0007431 | traceable author statement salivary gland development ; GO:0007431 | inferred from mutant phenotype larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from genetic interaction with dpp positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "CREB, dCREBA, CREB-a, CREB-A, dCreb-A, dCREB-A, crebA, dCrebA, Creb, creb, BOX B Binding Factor-2, BBF2_DROME, BBF-2, Creb-A, l(3)03576, CG7450, Bbbf2, BcDNA:SD05937, CrebA, CRE-BP, Creb A, CREBA, DM4" "IPR004827:Basic-leucine zipper domain, IPR001630:cAMP response element binding (CREB) protein" CG7450 11-Aug-17 DroID_v2017_08 "Drer\creb3l3a, Drer\creb3l2, Drer\creb3l3l, Drer\creb3l1, Drer\creb3l3b" "Scer\ARR1, Scer\CAD1" Cele\crh-2 "Xtro\creb3, Xtro\creb3l4" "Mmus\Creb3l4, Mmus\Creb3l2, Mmus\Creb3l3, Mmus\Creb3, Mmus\Creb3l1" "Hsap\CREB3L4, Hsap\CREB3L2, Hsap\CREB3L1, Hsap\CREB3, Hsap\CREB3L3" " adult stage | male , adult stage , larval stage | third instar , embryonic stage , adult stage && oogenesis stage , embryonic stage -- adult stage " " ejaculatory duct

, adult midgut

, ejaculatory bulb

, embryonic/larval digestive system

, seminal vesicle

, embryonic/larval salivary gland

, embryonic/larval fat body

, embryonic/larval trachea

, follicle cell

, adult brain

, optic lobe

, adult salivary gland

,

, adult proventriculus

" " embryonic stage | stage 11-12 , oogenesis stage && adult stage | female " " embryonic salivary gland

, ovary

" "visible,somatic clone,viable,fertile,lethal,recessive,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "larva,embryonic/larval cuticle,denticle belt,ommatidium,somatic clone,eye photoreceptor cell,embryonic/larval salivary gland,eye,ectopic" FBgn0016928 smi27E smell impaired 27E http://flybase.org/reports/FBgn0016928 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi27E - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0030321 CG1703 - http://flybase.org/reports/FBgn0030321 protein_coding_gene "ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871" - - CG1703 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR032781:ABC-transporter extension domain" CG1703 11-Aug-17 DroID_v2017_08 "Drer\abcf2a, Drer\abcf1, Drer\abcf3, Drer\abcf2b" Scer\GCN20 Cele\abcf-1 "Xtro\abcf3, Xtro\abcf1" "Mmus\Abcf2, Mmus\Abcf1, Mmus\Abcf3" "Hsap\ABCF2, Hsap\ABCF1, Hsap\ABCF3" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0031763 CG13996 - http://flybase.org/reports/FBgn0031763 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13996 "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG13996 11-Aug-17 DroID_v2017_08 - - - - - Hsap\SAMD15 viable FBgn0082672 Fill Firewall http://flybase.org/reports/FBgn0082672 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available Fill - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060557 l(3)S097405 lethal (3) S097405 http://flybase.org/reports/FBgn0060557 gene - - - "0974/05, l(3)S097405" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0026390 Or33c Odorant receptor 33c http://flybase.org/reports/FBgn0026390 - protein_coding_gene "olfactory receptor activity ; GO:0004984 | non-traceable author statement inferred by curator from GO:0004888,GO:0007608 olfactory receptor activity ; GO:0004984 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model" sensory perception of smell ; GO:0007608 | inferred from expression pattern sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from sequence model "33c, DOR71, CG5006, AN2, 33B.3, dor71, DOR33B.3, Or71, Or33B.3, Or33c" "IPR004117:Olfactory receptor, insect" CG5006 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage ," sensory neuron &&of maxillary palpus

viable DRSC03388 I -1.530345874 0.792747505 -0.20167203 0.024674066 -0.858406151 -0.192978813 FBgn0037460 sowi solwind http://flybase.org/reports/FBgn0037460 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" - - "sowi, CG15178" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG15178 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-103a14.5, Drer\rcvrna, Drer\kcnip2, Drer\guca1a, Drer\kcnip1b, Drer\guca1c, Drer\guca1g, Drer\hpcal4, Drer\kcnip1a, Drer\vsnl1a, Drer\kcnip4, Drer\rcvrn2, Drer\kcnip3b, Drer\guca1e, Drer\efcab1, Drer\ncaldb, Drer\guca1d, Drer\usp32, Drer\guca1b, Drer\ncs1b, Drer\rcvrn3, Drer\si:ch211-245j22.3, Drer\vsnl1b, Drer\ncs1a, Drer\hpcal1, Drer\rcvrnb, Drer\si:ch211-145b13.5, Drer\ncalda, Drer\hpca" Scer\FRQ1 - "Xtro\kcnip2, Xtro\guca1b, Xtro\ncs1, Xtro\guca1a, Xtro\guca1c, Xtro\hpca, Xtro\vsnl1, Xtro\kcnip1, Xtro\kcnip4, Xtro\kcnip3, Xtro\efcab1, Xtro\ncald, Xtro\rcvrn.2, Xtro\hpcal1" "Mmus\Kcnip2, Mmus\Usp32, Mmus\Hpca, Mmus\Guca1a, Mmus\Hpcal4, Mmus\Vsnl1, Mmus\Ncald, Mmus\Efcab1, Mmus\Kcnip4, Mmus\1700109H08Rik, Mmus\Ncs1, Mmus\Hpcal1, Mmus\Kcnip3, Mmus\Kcnip1, Mmus\Rcvrn, Mmus\Guca1b" "Hsap\USP32, Hsap\KCNIP1, Hsap\GUCA1B, Hsap\NCS1, Hsap\VSNL1, Hsap\KCNIP4, Hsap\KCNIP3, Hsap\KCNIP2, Hsap\GUCA1C, Hsap\EFCAB1, Hsap\HPCA, Hsap\RCVRN, Hsap\GUCA1A, Hsap\HPCAL1, Hsap\NCALD, Hsap\HPCAL4" viable DRSC12558 I 2.295027094 -0.184820699 -0.06168727 -0.059210542 -0.731451177 0.151891585 FBgn0028871 Cpr35B Cuticular protein 35B http://flybase.org/reports/FBgn0028871 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of pupal chitin-based cuticle ; GO:0008011 | inferred from sequence or structural similarity structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "DS06283.4, BG:DS06238.4, Cpr35B, CG3474, DmelCpr35B" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG3474 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0024661 l(2)k07020 lethal (2) k07020 http://flybase.org/reports/FBgn0024661 - gene - - - "70/20, l(2)k07020" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263083 CG43351 - http://flybase.org/reports/FBgn0263083 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43351, CG42725" - CG43351 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261681 CG42728 - http://flybase.org/reports/FBgn0261681 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG7973, CG17014, CG33984, CG42728" IPR002557:Chitin binding domain CG42728 11-Aug-17 DroID_v2017_08 - - "Cele\cbd-1, Cele\W03F11.1" - - - FBgn0038881 CG16791 - http://flybase.org/reports/FBgn0038881 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype - "anon-WO0172774.78, CG16791, R5_3R:17143989..17145881" IPR015943:WD40/YVTN repeat-like-containing domain CG16791 11-Aug-17 DroID_v2017_08 - - Cele\C26D10.6 - - - "viable,fertile" DRSC13471 IE -0.122468117 1.672170139 -4.424384737 0.02084262 0.418129969 1.2766258 FBgn0065337 l(2)SH1846 lethal (2) SH1846 http://flybase.org/reports/FBgn0065337 gene - - - "l(2)SH1846, l(2)SH2 1846" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044352 Quasimodo\pol Quasimodo element pol http://flybase.org/reports/FBgn0044352 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "cruiser\pol, Quasimodo\pol" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261730 EC1650 - http://flybase.org/reports/FBgn0261730 gene - - - EC1650 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0004071 fs(2)mel5 female sterile (2) maternal effect lethal 5 http://flybase.org/reports/FBgn0004071 - gene - - - "mel 5, fs(2)mel5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" FBgn0031258 CG4297 - http://flybase.org/reports/FBgn0031258 protein_coding_gene - - - CG4297 - CG4297 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031196 CG17599 - http://flybase.org/reports/FBgn0031196 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence model cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000489125 intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:1924029 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000489125 intraciliary transport particle B ; GO:0030992 | inferred from biological aspect of ancestor with PANTHER:PTN000489125 cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN000489125 cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:1924029 "CG17599, CLUAP1" IPR019366:Clusterin-associated protein-1 CG17599 11-Aug-17 DroID_v2017_08 Drer\cluap1 - Cele\dyf-3 Xtro\cluap1 Mmus\Cluap1 Hsap\CLUAP1 viable FBgn0029705 CG12693 - http://flybase.org/reports/FBgn0029705 protein_coding_gene - - - CG12693 - CG12693 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000312 cht chaetae http://flybase.org/reports/FBgn0000312 - gene - - - cht - - 11-Aug-17 DroID_v2017_08 - - - - - - scutellar bristle FBgn0053805 His-Psi:CR33805 His-Psi:CR33805 http://flybase.org/reports/FBgn0053805 pseudogene_attribute - - - "CR33805, His-Psi:CR33805" - CR33805 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058100 CR40100 - http://flybase.org/reports/FBgn0058100 pseudogene_attribute - - - "CR40100, CG40100" - CR40100 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019796 l(1)10 lethal (1) 10 http://flybase.org/reports/FBgn0019796 - gene - - - l(1)10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030195 CG2898 - http://flybase.org/reports/FBgn0030195 protein_coding_gene - - - CG2898 - CG2898 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,visible" tormogen cell FBgn0002054 l(2)37Fg lethal (2) 37Fg http://flybase.org/reports/FBgn0002054 - gene - - - "l(2)O9, l(2)37Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020554 cro croaker http://flybase.org/reports/FBgn0020554 - gene - "male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement" - cro - - 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,male,female,flight defective,wild-type" FBgn0040104 lectin-24A lectin-24A http://flybase.org/reports/FBgn0040104 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 galactose binding ; GO:0005534 | inferred from sequence or structural similarity - - "CG3410, AC005149a, AC 005149A, lectin-24A" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG3410 11-Aug-17 DroID_v2017_08 "Drer\clec3bb, Drer\clec11a, Drer\hbl2, Drer\colec11, Drer\clec3ba, Drer\hbl4, Drer\hbl1, Drer\hbl3, Drer\selp" - Cele\clec-149 "Xtro\clec3b, Xtro\clec3a, Xtro\colec10, Xtro\sftpa" "Mmus\Clec10a, Mmus\Klri1, Mmus\Asgr1, Mmus\Cd207, Mmus\Mgl2, Mmus\Colec11, Mmus\Asgr2, Mmus\Sftpa1, Mmus\Clec3b, Mmus\Mbl1, Mmus\Klri2" "Hsap\COLEC10, Hsap\CLEC12B, Hsap\SFTPA2, Hsap\COLEC11, Hsap\SFTPA1, Hsap\CLEC3A, Hsap\CLEC4A, Hsap\CLEC3B, Hsap\MBL2, Hsap\CLEC17A, Hsap\SFTPD, Hsap\SELE" viable FBgn0030874 Spt7 Spt7 http://flybase.org/reports/FBgn0030874 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay "CG6506, dSpt7, Spt7, cg6506" - CG6506 11-Aug-17 DroID_v2017_08 Drer\supt7l - - Xtro\supt7l Mmus\Supt7l Hsap\SUPT7L viable FBgn0266321 CR44986 - http://flybase.org/reports/FBgn0266321 non_protein_coding_gene - - - CR44986 - CR44986 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003602 Su(var)3-11 Suppressor of variegation 3-11 http://flybase.org/reports/FBgn0003602 - gene - - - "Su(var)3-111, Su-var(3)111, Su-var(3)11, Su(var)3-11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065509 l(2)SH1180 lethal (2) SH1180 http://flybase.org/reports/FBgn0065509 gene - - - "l(2)SH1180, l(2)SH2 1180" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265716 CR44523 - http://flybase.org/reports/FBgn0265716 non_protein_coding_gene - - - "incRNA.457, CR44523, lincRNA.457" - CR44523 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024260 acd(2)5N15 auditory courtship defective 5N15 http://flybase.org/reports/FBgn0024260 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5N15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective" FBgn0011188 l(1)296-13 lethal (1) 296-13 http://flybase.org/reports/FBgn0011188 FBgn0010201 gene - - - "296-13, l(1)296-13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000192 Bkm BKM sequence element http://flybase.org/reports/FBgn0000192 - satellite_DNA - - - "BKM, Bkm" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014048 Su(tor)2-237 Su(tor)2-237 http://flybase.org/reports/FBgn0014048 - gene - - - Su(tor)2-237 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0034925 CG5339 - http://flybase.org/reports/FBgn0034925 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG5339, drev" "IPR007884:DREV methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG5339 11-Aug-17 DroID_v2017_08 Drer\mettl9 - Cele\T03G11.6 Xtro\mettl9 Mmus\Mettl9 Hsap\METTL9 viable FBgn0085527 CG40858 - http://flybase.org/reports/FBgn0085527 protein_coding_gene - - - CG40858 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029811 Cpr5C Cuticular protein 5C http://flybase.org/reports/FBgn0029811 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr5C, CG4052" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG4052 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0086245 grk::yl - http://flybase.org/reports/FBgn0086245 engineered_fusion_gene - - - "grk::yl, Grk-Yl" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005377 x8 x8 http://flybase.org/reports/FBgn0005377 - gene - - - x8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032085 CG9555 - http://flybase.org/reports/FBgn0032085 protein_coding_gene - - - CG9555 - CG9555 11-Aug-17 DroID_v2017_08 - - "Cele\C46E10.2, Cele\srd-56" - - - "viable,fertile" FBgn0084815 CG11091 - http://flybase.org/reports/FBgn0084815 protein_coding_gene - - - CG11091 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC17199 IE -1.630446028 -0.978279208 -1.975595126 -0.4317093 0.85163185 0.272000638 FBgn0060833 l(3)S050110b lethal (3) S050110b http://flybase.org/reports/FBgn0060833 gene - - - "0501/10, l(3)S050110b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0037514 CG10919 - http://flybase.org/reports/FBgn0037514 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10919 IPR032004:Protein of unknown function DUF4790 CG10919 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0011247 ms(3)90E male sterile (3) 90E http://flybase.org/reports/FBgn0011247 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - ms(3)90E - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,partially lethal - majority die" FBgn0001042 fs(3)HO5B female sterile (3) HO5B http://flybase.org/reports/FBgn0001042 - gene - - - "fs(3)f2, fs(3)f2[5A], fs(3)HO5B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0033554 Lsm10 Lsm10 http://flybase.org/reports/FBgn0033554 protein_coding_gene - mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype mRNA processing ; GO:0006397 | inferred from direct assay cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay histone locus body ; GO:0035363 | inferred from direct assay nuclear body ; GO:0016604 | inferred from direct assay "Lsm10, CG12938, dLsm10" "IPR010920:LSM domain, IPR001163:LSM domain, eukaryotic/archaea-type" CG12938 11-Aug-17 DroID_v2017_08 "Drer\snrpd1, Drer\lsm10" Scer\SMD1 Cele\K07A1.15 "Xtro\lsm10, Xtro\snrpd1" "Mmus\Lsm10, Mmus\Snrpd1" "Hsap\SNRPD1, Hsap\LSM10" "viable,fertile,male fertile,female fertile,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0040860 CG11264 - http://flybase.org/reports/FBgn0040860 protein_coding_gene - - - CG11264 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000189 bk buckled http://flybase.org/reports/FBgn0000189 - gene - - - bk - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,male fertile" "wing,wing vein,eye,scutellar bristle,leg,sex comb,macrochaeta" FBgn0261570 CG42684 - http://flybase.org/reports/FBgn0261570 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 "negative regulation of angiogenesis ; GO:0016525 | inferred from electronic annotation with InterPro:IPR030403 reelin-mediated signaling pathway ; GO:0038026 | inferred from electronic annotation with InterPro:IPR030403 negative regulation of vascular endothelial growth factor receptor signaling pathway ; GO:0030948 | inferred from electronic annotation with InterPro:IPR030403 negative regulation of cell proliferation ; GO:0008285 | inferred from electronic annotation with InterPro:IPR030403 positive regulation of apoptotic process ; GO:0043065 | inferred from electronic annotation with InterPro:IPR030403 regulation of GTPase activity ; GO:0043087 | inferred from electronic annotation with InterPro:IPR001936, InterPro:IPR023152 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from sequence or structural similarity with UniProtKB:Q8MLZ5 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" intrinsic component of the cytoplasmic side of the plasma membrane ; GO:0031235 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 apical cortex ; GO:0045179 | inferred from direct assay "CG42684, CG32560, CG42270, CG32559, CG5960, CG5898, CG15816, FBpp0112350" "IPR000008:C2 domain, IPR001936:Ras GTPase-activating protein, IPR008936:Rho GTPase activation protein, IPR023152:Ras GTPase-activating protein, conserved site, IPR021887:Domain of unknown function DUF3498, IPR011993:PH domain-like, IPR030403:Disabled homologue 2-interacting protein, IPR023315:SynGAP C2 domain, N-terminal, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG42684 11-Aug-17 DroID_v2017_08 "Drer\dab2ipa, Drer\rasa1a, Drer\syngap1a, Drer\rasal3, Drer\rasal2, Drer\syngap1b, Drer\rasa1b, Drer\dab2ipb" "Scer\IRA2, Scer\IRA1, Scer\BUD2" Cele\gap-2 "Xtro\rasal1, Xtro\rasa1, Xtro\syngap1, Xtro\rasal3, Xtro\rasal2" "Mmus\Rasal1, Mmus\Syngap1, Mmus\Rasal2, Mmus\Rasa1, Mmus\Rasal3, Mmus\Dab2ip" "Hsap\RASAL1, Hsap\RASA1, Hsap\DAB2IP, Hsap\RASAL2, Hsap\RASAL3, Hsap\SYNGAP1" FBgn0259473 C502 - http://flybase.org/reports/FBgn0259473 gene - - - C502 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0019868 anon-B2 anon-B2 http://flybase.org/reports/FBgn0019868 - gene - - - "B2, anon-B2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002660 mat(2)cell-I maternal effect cellularisation defect I http://flybase.org/reports/FBgn0002660 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)cellQQ55, mat(2)cell-I" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" "stage 5 embryo,embryonic/first instar larval cuticle" FBgn0044346 scratch-like1 scratch-like1 http://flybase.org/reports/FBgn0044346 gene - - - scratch-like1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051081 TwdlR TweedleR http://flybase.org/reports/FBgn0051081 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "CG14241, TwdlR, CG14240, CG31081" IPR004145:Domain of unknown function DUF243 CG31081 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259354 C367 - http://flybase.org/reports/FBgn0259354 gene - - - C367 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing hair,chaeta" FBgn0062928 pncr009:3L putative noncoding RNA 009:3L http://flybase.org/reports/FBgn0062928 pseudogene_attribute - - - "CR33940, BcDNA:RH57193, pncr009:3L, pncr009, hp-pncr009" - CR33940 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011999 tRNA:Val-CAC-2-1 transfer RNA:Valine-CAC 2-1 http://flybase.org/reports/FBgn0011999 "FBgn0003853, FBgn0011997, FBgn0051512, FBgn0060024" tRNA_gene GUG codon-amino acid adaptor activity ; GO:0033452 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033452 cytosol ; GO:0005829 | inferred by curator from GO:0033452 "valine tRNA, tRNA[Val][[3b]], Val-3b, AE002699.trna12-ValCAC, tRNA:V3b, tRNA:V:CAC:AE002699-c, CR31512, tRNA:val3b:84Db, chr3R.trna5-ValCAC, tRNA:Val-CAC-2-1, tRNA:V3b:84Db, tRNA-Val-CAC-2-1, GUG" - CR31512 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034086 CG8441 - http://flybase.org/reports/FBgn0034086 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from biological aspect of ancestor with PANTHER:PTN000337723 protein kinase inhibitor activity ; GO:0004860 | inferred from biological aspect of ancestor with PANTHER:PTN000337723 double-stranded RNA binding ; GO:0003725 | inferred from biological aspect of ancestor with PANTHER:PTN000337723 negative regulation of protein kinase activity ; GO:0006469 | inferred from biological aspect of ancestor with PANTHER:PTN000337723 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000337723 CG8441 IPR009548:Protein of unknown function DUF1168 CG8441 11-Aug-17 DroID_v2017_08 Drer\prkrip1 - Cele\F37A4.2 Xtro\prkrip1 Mmus\Prkrip1 Hsap\PRKRIP1 "viable,visible" trichogen cell FBgn0043038 l(2)42Bf lethal (2) 42Bf http://flybase.org/reports/FBgn0043038 gene - - - l(2)42Bf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051739 AspRS-m "Aspartyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0051739 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004115, InterPro:IPR004364, InterPro:IPR004524, InterPro:IPR018150 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004365 aminoacyl-tRNA ligase activity ; GO:0004812 | inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004115, InterPro:IPR004364, InterPro:IPR006195, InterPro:IPR018150 aspartate-tRNA ligase activity ; GO:0004815 | traceable author statement" "tRNA aminoacylation for protein translation ; GO:0006418 | inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004364, InterPro:IPR006195, InterPro:IPR018150 aspartyl-tRNA aminoacylation ; GO:0006422 | traceable author statement" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004115 mitochondrion ; GO:0005739 | traceable author statement "CG17938, CG31739, AspRS-m" "IPR002312:Aspartyl/Asparaginyl-tRNA synthetase, class IIb, IPR004364:Aminoacyl-tRNA synthetase, class II (D/K/N), IPR004365:OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR004524:Aspartate-tRNA ligase, type 1, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR012340:Nucleic acid-binding, OB-fold, IPR004115:GAD-like domain" CG31739 11-Aug-17 DroID_v2017_08 Drer\dars2 Scer\MSD1 Cele\dars-2 Xtro\dars2 Mmus\Dars2 Hsap\DARS2 "viable,fertile,visible" trichogen cell FBgn0263130 CR43372 - http://flybase.org/reports/FBgn0263130 non_protein_coding_gene - - - CR43372 - CR43372 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004142 GATA-sequence GATA element http://flybase.org/reports/FBgn0004142 - repeat_region - - - "GATA9, GATA6, GATA5, GATA4, GATA12, GATA, GATA-sequence" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266218 CR44913 - http://flybase.org/reports/FBgn0266218 non_protein_coding_gene - - - CR44913 - CR44913 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024546 l(3)L3560 lethal (3) L3560 http://flybase.org/reports/FBgn0024546 - gene - - - l(3)L3560 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004684 ju jumper http://flybase.org/reports/FBgn0004684 - gene - - - ju - - 11-Aug-17 DroID_v2017_08 - - - - - - flightless wing FBgn0263650 CR43641 - http://flybase.org/reports/FBgn0263650 non_protein_coding_gene - - - CR43641 - CR43641 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022093 l(2)k07245 lethal (2) k07245 http://flybase.org/reports/FBgn0022093 - gene - - - l(2)k07245 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000974 fs(2)HO20 female sterile (2) HO20 http://flybase.org/reports/FBgn0000974 - gene - - - "fs(2)20B, fs(2)HO20" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" ovary FBgn0026344 Su(rdgB)83 Su(rdgB)83 http://flybase.org/reports/FBgn0026344 - gene - - - Su(rdgB)83 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010144 l(3)62Bh lethal (3) 62Bh http://flybase.org/reports/FBgn0010144 - gene - - - "dre5, l(3)Bh, l(3)dre5, l(3)62Bh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0265098 CR44203 - http://flybase.org/reports/FBgn0265098 non_protein_coding_gene - - - CR44203 - CR44203 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013547 l(2)Su(Sp) lethal (2) Su(Sp) http://flybase.org/reports/FBgn0013547 - gene - - - l(2)Su(Sp) - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259254 EP-620 - http://flybase.org/reports/FBgn0259254 gene - - - EP-620 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing hair,wing,wing vein" FBgn0264519 btl::ft - http://flybase.org/reports/FBgn0264519 engineered_fusion_gene - - - btl::ft - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050006 CG30006 - http://flybase.org/reports/FBgn0050006 protein_coding_gene - - - CG30006 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000161 bat bat http://flybase.org/reports/FBgn0000161 - gene - - - "ext-b, bat" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0001426 l(1)6Eb lethal (1) 6Eb http://flybase.org/reports/FBgn0001426 - gene - - - "JNLX, jnLX, l(1)jnLX, l(1)6Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal,lethal - all die before end of pupal stage,some die during pupal stage" wing FBgn0034005 ItgaPS4 Integrin alphaPS4 subunit http://flybase.org/reports/FBgn0034005 protein_coding_gene receptor activity ; GO:0004872 | inferred from sequence or structural similarity with scb cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity with scb protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with mys cell-matrix adhesion ; GO:0007160 | traceable author statement heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | traceable author statement cell adhesion mediated by integrin ; GO:0033627 | inferred from sequence or structural similarity with mys oocyte growth ; GO:0001555 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mys integrin complex ; GO:0008305 | inferred from sequence or structural similarity integrin complex ; GO:0008305 | non-traceable author statement integrin complex ; GO:0008305 | inferred from sequence or structural similarity with mys integrin complex ; GO:0008305 | inferred from sequence or structural similarity with scb "alpha-ps4, CT37393, alphaPS4, CG16827, alpha-PS4, ItgaPS4, ItgalphaPS4" "IPR000413:Integrin alpha chain, IPR013519:Integrin alpha beta-propellor, IPR013649:Integrin alpha-2, IPR018184:Integrin alpha chain, C-terminal cytoplasmic region, conserved site, IPR032695:Integrin domain" CG16827 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-32n7.4, Drer\itgae.1, Drer\itga3a, Drer\itga2.2, Drer\itga6a, Drer\itga4, Drer\itga1, Drer\itgam, Drer\zmp:0000001082, Drer\itga11b, Drer\itga10, Drer\itga6l, Drer\itga11a, Drer\itgae.2, Drer\itga9, Drer\itga6b, Drer\itga3b" Scer\YJL132W Cele\ina-1 "Xtro\itga4, Xtro\itga2, Xtro\itga9, Xtro\itga11, Xtro\itga1, Xtro\itga8" "Mmus\Itgae, Mmus\Gpld1, Mmus\Itgal, Mmus\Itga2, Mmus\Itga9, Mmus\Itgam, Mmus\Itga7, Mmus\Itga4, Mmus\Itga11, Mmus\Itgad, Mmus\Itga6, Mmus\Itga1, Mmus\Itga3, Mmus\Itgax, Mmus\Itga10" "Hsap\ITGA7, Hsap\ITGAX, Hsap\GPLD1, Hsap\ITGA3, Hsap\ITGA2, Hsap\ITGA9, Hsap\ITGA6, Hsap\ITGA1, Hsap\ITGA11, Hsap\ITGA4, Hsap\ITGAD, Hsap\ITGAM, Hsap\ITGAL, Hsap\ITGAE, Hsap\ITGA10, Hsap\ITGA8" viable FBgn0058254 CR40254 - http://flybase.org/reports/FBgn0058254 non_protein_coding_gene - - - CR40254 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259228 C3G C3G guanyl-nucleotide exchange factor http://flybase.org/reports/FBgn0259228 protein_coding_gene Rap guanyl-nucleotide exchange factor activity ; GO:0017034 | inferred from direct assay Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay somatic muscle development ; GO:0007525 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from direct assay Ras protein signal transduction ; GO:0007265 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG42328, C(3)G, DC3G, CG3126, C3G, CG14436, DC3-G, c(3)G" "IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR023578:Ras guanine nucleotide exchange factor domain, IPR019804:Ras guanine-nucleotide exchange factor, conserved site" CG42328 11-Aug-17 DroID_v2017_08 "Drer\rapgef1a, Drer\sos1, Drer\rasgrf2b, Drer\rapgef1b, Drer\si:ch211-234p18.3" "Scer\CDC25, Scer\LTE1" "Cele\sos-1, Cele\pxf-1, Cele\rgl-1, Cele\Y34B4A.4" Xtro\rapgef1 "Mmus\Sos2, Mmus\Rapgef1, Mmus\Rapgef2, Mmus\Sos1, Mmus\Rasgrf1, Mmus\Rasgrf2, Mmus\Rapgef6" "Hsap\RASGRF1, Hsap\SOS1, Hsap\RASGRF2, Hsap\RAPGEF2, Hsap\SOS2, Hsap\RAPGEF1" " embryonic stage | stage >=4 , embryonic stage | stage 14 , embryonic stage | stage 14 | late , embryonic stage | stage 11 " " embryonic/larval foregut

, segment | segmentally repeated pattern

, visceral mesoderm

, embryonic/larval hindgut

" FBgn0065727 l(2)SH0559 lethal (2) SH0559 http://flybase.org/reports/FBgn0065727 gene - - - "l(2)SH0559, l(2)SH2 0559" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265454 CR44354 - http://flybase.org/reports/FBgn0265454 non_protein_coding_gene - - - CR44354 - CR44354 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267040 CR45484 - http://flybase.org/reports/FBgn0267040 non_protein_coding_gene - - - "lincRNA.947, CR45484" - CR45484 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040187 l(1)G0214 lethal (1) G0214 http://flybase.org/reports/FBgn0040187 gene - - - l(1)G0214 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,male,female,recessive" FBgn0062592 Mod(var)1552 Mod(var)1552 http://flybase.org/reports/FBgn0062592 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1552, Mod(var)1552" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0002106 l(2)57Ec lethal (2) 57Ec http://flybase.org/reports/FBgn0002106 - gene - - - "l(2)57DEFc, l(2)ES15, l(2)57Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052570 TwdlY TweedleY http://flybase.org/reports/FBgn0052570 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlY, CG32570" IPR004145:Domain of unknown function DUF243 CG32570 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264310 CR43785 - http://flybase.org/reports/FBgn0264310 non_protein_coding_gene - - - "CR43785, lincRNA.405" - CR43785 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260058 2L4081 - http://flybase.org/reports/FBgn0260058 gene - - - 2L4081 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0085692 CG41561 - http://flybase.org/reports/FBgn0085692 protein_coding_gene - - - CG41561 - CG41561 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265255 CR44269 - http://flybase.org/reports/FBgn0265255 non_protein_coding_gene - - - "CR44269, lincRNA.218" - CR44269 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034442 CG11257 - http://flybase.org/reports/FBgn0034442 protein_coding_gene "cytochrome-b5 reductase activity, acting on NAD(P)H ; GO:0004128 | inferred from electronic annotation with InterPro:IPR033566 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000452136" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001433, InterPro:IPR001834, InterPro:IPR017927, InterPro:IPR017938" - CG11257 "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR001834:NADH:cytochrome b5 reductase (CBR), IPR008333:Oxidoreductase, FAD-binding domain, IPR018506:Cytochrome b5, heme-binding site, IPR008978:HSP20-like chaperone, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel, IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR033566:Cytochrome b5 reductase 4" CG11257 11-Aug-17 DroID_v2017_08 "Drer\cyb5r3, Drer\cyb5r4, Drer\cyb5r1, Drer\cyb5r2, Drer\oxnad1" "Scer\AIM33, Scer\YHB1, Scer\CYC2, Scer\PGA3, Scer\MCR1, Scer\CBR1, Scer\IRC21" Cele\Y52B11A.3 "Xtro\cyb5r4, Xtro\cyb5r3, Xtro\oxnad1, Xtro\cyb5r1, Xtro\cyb5r2" "Mmus\Cyb5r4, Mmus\Cyb5r3, Mmus\Cyb5r2, Mmus\Cyb5rl, Mmus\Cyb5r1, Mmus\Oxnad1" "Hsap\CYB5RL, Hsap\OXNAD1, Hsap\CYB5R3, Hsap\CYB5R1, Hsap\CYB5R2, Hsap\CYB5R4" "viable,fertile" FBgn0267451 CR45801 - http://flybase.org/reports/FBgn0267451 non_protein_coding_gene - - - "CR45801, AT12039" - CR45801 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011566 Smyd3 "SET and MYND domain containing, class 3" http://flybase.org/reports/FBgn0011566 FBgn0029628 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 - cellular_component ; GO:0005575 | no biological data available "CG13761, EG:BACR7C10.4, Smyd3, Bzd" "IPR002893:Zinc finger, MYND-type, IPR011990:Tetratricopeptide-like helical domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG13761 11-Aug-17 DroID_v2017_08 "Drer\smyd2b, Drer\smyd4, Drer\smyd1b, Drer\smyd3, Drer\smyd2a, Drer\smyd1a" "Scer\SET5, Scer\SET6" "Cele\set-18, Cele\set-14, Cele\set-30, Cele\set-10" "Xtro\smyd5, Xtro\smyd1, Xtro\smyd4, Xtro\crls1, Xtro\smyd3" "Mmus\Smyd4, Mmus\Smyd1, Mmus\Smyd5, Mmus\Smyd2, Mmus\Smyd3, Mmus\Zmynd15" "Hsap\SMYD2, Hsap\ZMYND15, Hsap\SMYD3, Hsap\SMYD4, Hsap\SMYD5, Hsap\SMYD1" FBgn0065769 l(2)SH0467 lethal (2) SH0467 http://flybase.org/reports/FBgn0065769 gene - - - "l(2)SH0467, l(2)SH2 0467" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016946 tilC touch insensitive larva C http://flybase.org/reports/FBgn0016946 - gene - - - tilC - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0034221 CG10764 - http://flybase.org/reports/FBgn0034221 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model negative regulation of hemocyte proliferation ; GO:0035207 | inferred from genetic interaction with hop" - "SP77, gene 2, GENE 2, anon-54Ba, CG10764, FBgn0034221" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG10764 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.9, Drer\gzm3, Drer\si:ch211-165b19.5, Drer\si:dkey-21e2.7, Drer\si:dkey-21e2.15, Drer\si:dkey-21e2.12" - Cele\try-3 - "Mmus\Gzmb, Mmus\Gzmc, Mmus\Klk6, Mmus\Mcpt9, Mmus\Mcpt4, Mmus\Gzmd, Mmus\Cma2, Mmus\Gzmf, Mmus\Gzme, Mmus\Mcpt1, Mmus\Mcpt8, Mmus\Cma1, Mmus\Gzmg, Mmus\Ctsg" "Hsap\GZMB, Hsap\GZMH, Hsap\CMA1, Hsap\CTSG" "viable,visible" trichogen cell FBgn0050333 tRNA:Phe-GAA-1-4 transfer RNA:Phenylalanine-GAA 1-4 http://flybase.org/reports/FBgn0050333 tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "AE002787.trna11-PheGAA, tRNA:F:GAA:AE002787-a, CR30230, CR30333, chr2R.trna69-PheGAA, tRNA-Phe-GAA-1-4, tRNA:Phe-GAA-1-4, tRNA:CR30333, UUC" - CR30333 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038830 CG17272 - http://flybase.org/reports/FBgn0038830 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "BEST:GH27755, CG17272, ELC5" "IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG17272 11-Aug-17 DroID_v2017_08 "Drer\cabp2b, Drer\cabp5a, Drer\pvalb8, Drer\cabp5b, Drer\calm2b, Drer\tnnc1b, Drer\pvalb3, Drer\pvalb4, Drer\cabp1b, Drer\calm2a, Drer\calb1, Drer\tnnc1a, Drer\tnnc2, Drer\pvalb2, Drer\calb2a, Drer\cabp4, Drer\pvalb1, Drer\calb2b, Drer\pvalb9, Drer\efcab11, Drer\cabp2a, Drer\calm1a, Drer\calml4b, Drer\calm3b, Drer\rhbdl3, Drer\calm3a, Drer\calml4a, Drer\cabp7b, Drer\caln2, Drer\scgn, Drer\cabp1a, Drer\calm1b, Drer\caln1, Drer\si:ch211-197n1.2, Drer\efcab2, Drer\efcab6, Drer\pvalb6" "Scer\MLC2, Scer\MLC1, Scer\CMD1" "Cele\cmd-1, Cele\cal-4, Cele\T09B4.4, Cele\cal-2, Cele\cal-1, Cele\cal-3" "Xtro\cabp4, Xtro\calm1, Xtro\cabp7, Xtro\scgn, Xtro\pvalb, Xtro\calb1, Xtro\efcab6, Xtro\pgm1, Xtro\calml4, Xtro\tnnc2, Xtro\ocm, Xtro\tnnc1, Xtro\ocm.2, Xtro\pvalb.1, Xtro\calm2, Xtro\pvalb.2, Xtro\LOC548651" "Mmus\Cabp5, Mmus\Efcab9, Mmus\Efcab6, Mmus\Calb2, Mmus\Calm5, Mmus\Calml3, Mmus\Tnnc2, Mmus\Calb1, Mmus\Efcab3, Mmus\Cabp1, Mmus\Calm1, Mmus\Rhbdl3, Mmus\Efcab7, Mmus\Pvalb, Mmus\Ocm, Mmus\Calm4, Mmus\Tnnc1, Mmus\Cabp4, Mmus\Cabp7, Mmus\Efcab2, Mmus\Cabp2, Mmus\1700023F06Rik, Mmus\Calml4, Mmus\Efcab11, Mmus\Caln1, Mmus\Scgn, Mmus\Calm2, Mmus\Calm3, Mmus\Spata21" "Hsap\CALN1, Hsap\CALB1, Hsap\OCM2, Hsap\CALM2, Hsap\CABP5, Hsap\EFCAB13, Hsap\CABP4, Hsap\EFCAB7, Hsap\CABP7, Hsap\CALML3, Hsap\CALB2, Hsap\TNNC1, Hsap\CABP2, Hsap\SCGN, Hsap\EFCAB9, Hsap\EFCAB6, Hsap\OCM, Hsap\CABP1, Hsap\CALM3, Hsap\TNNC2, Hsap\CALM1, Hsap\EFCAB3, Hsap\CALML4, Hsap\CALML6, Hsap\RHBDL3, Hsap\EFCAB2, Hsap\EFCAB11, Hsap\PVALB, Hsap\CALML5, Hsap\SPATA21" viable FBgn0036882 CG9279 - http://flybase.org/reports/FBgn0036882 protein_coding_gene dynein complex binding ; GO:0070840 | inferred from electronic annotation with InterPro:IPR027663 transport along microtubule ; GO:0010970 | inferred from electronic annotation with InterPro:IPR027663 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynactin complex ; GO:0005869 | inferred from sequence or structural similarity with DCTN1-p150 "CG9279, P150B" "IPR000938:CAP Gly-rich domain, IPR027663:Dynactin subunit 1, IPR022157:Dynein associated protein" CG9279 11-Aug-17 DroID_v2017_08 "Drer\dctn1a, Drer\dctn1b" Scer\ALF1 Cele\dnc-1 Xtro\dctn1 Mmus\Dctn1 Hsap\DCTN1 viable FBgn0261801 CG42747 - http://flybase.org/reports/FBgn0261801 protein_coding_gene - - - "CG42747, CG14910, CG14911" - CG42747 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004362 HmgD High mobility group protein D http://flybase.org/reports/FBgn0004362 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay AT DNA binding ; GO:0003680 | inferred from direct assay DNA binding, bending ; GO:0008301 | inferred from direct assay" muscle organ development ; GO:0007517 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay "HMG-D, hmg-D, clone 1.9, HMG D, dHMG-D, anon-EST:Liang-1.9, CG17950, HmgD, HMG-D100, Dm-HMG-D100, HMGD, Hmg-D, hmgd, HMG1" IPR009071:High mobility group box domain CG17950 11-Aug-17 DroID_v2017_08 "Drer\ubtf, Drer\tox3, Drer\ssrp1a, Drer\hmgb2b, Drer\hmgb3b, Drer\hmg20a, Drer\hmgb2a, Drer\tfam, Drer\tox, Drer\tox4b, Drer\ssrp1b, Drer\hmgb1a, Drer\hmgb1b, Drer\ubtfl, Drer\hmg20b, Drer\hmgb3a, Drer\tox4a" "Scer\IXR1, Scer\NHP10, Scer\NHP6A, Scer\NHP6B, Scer\POB3, Scer\HMO1, Scer\ABF2" "Cele\hmg-3, Cele\hmg-4, Cele\hmg-1.1" "Xtro\hmg20a, Xtro\hmgb3, Xtro\hmgb1, Xtro\hmg20b, Xtro\tox4, Xtro\tfam, Xtro\tox, Xtro\hmgb2, Xtro\tox2, Xtro\tox3, Xtro\ubtf" "Mmus\Hmgb4, Mmus\Tox3, Mmus\Hmgb3, Mmus\Tox4, Mmus\Hmg20b, Mmus\Hmgb1, Mmus\Hmg20a, Mmus\Ubtf, Mmus\Ssrp1, Mmus\Tox2, Mmus\Tox, Mmus\Tfam, Mmus\Hmgb2, Mmus\Ubtfl1" "Hsap\HMG20B, Hsap\HMGB2, Hsap\HMG20A, Hsap\HMGB3, Hsap\SSRP1, Hsap\TOX4, Hsap\TOX2, Hsap\TOX, Hsap\TFAM, Hsap\UBTF, Hsap\HMGB4, Hsap\HMGB1, Hsap\TOX3" " adult stage | female , embryonic stage | stage 11-15 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-6 , embryonic stage | stage 9-16 , embryonic stage | early , adult stage && oogenesis stage | stage S1-14 , embryonic stage , embryonic stage | stage >=9 " " embryonic peripheral nervous system | restricted

, germarium

, embryonic central nervous system

,

ubiquitous , nurse cell

, follicle cell

, neuroblast

" embryonic stage -- adult stage "learning defective,viable,partially lethal - majority live,lethal - all die before end of pupal stage,majority die during larval stage,some die during pupal stage,fertile,lethal - all die before end of P-stage,some die during P-stage,lethal,body color defective" "rhabdomere R7,mesothoracic tergum" FBgn0035475 CG10866 - http://flybase.org/reports/FBgn0035475 protein_coding_gene - - - CG10866 IPR026572:Transmembrane protein 267 CG10866 11-Aug-17 DroID_v2017_08 Drer\si:busm1-79m10.4 - - Xtro\c5orf28 Mmus\Tmem267 Hsap\TMEM267 "viable,fertile" FBgn0066358 l(2)214 lethal (2) 214 http://flybase.org/reports/FBgn0066358 gene - - - l(2)214 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0260628 d11677 - http://flybase.org/reports/FBgn0260628 gene - - - d11677 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0060643 l(3)S084015b lethal (3) S084015b http://flybase.org/reports/FBgn0060643 gene - - - "0840/15, l(3)S084015b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0002729 mfs(2)350 male female sterile 350 http://flybase.org/reports/FBgn0002729 - gene - - - "str(2)350, mfs(2)350" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,male sterile" "ovary,testis,spermatozoon" FBgn0264353 CR43809 - http://flybase.org/reports/FBgn0264353 non_protein_coding_gene - - - CR43809 - CR43809 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001886 l(2)21Bd lethal (2) 21Bd http://flybase.org/reports/FBgn0001886 - gene - - - l(2)21Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060823 l(3)S052001 lethal (3) S052001 http://flybase.org/reports/FBgn0060823 gene - - - "0520/01, l(3)S052001" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082685 E(ftz)2142 E(ftz)2142 http://flybase.org/reports/FBgn0082685 gene - - - "2142, E(ftz)2142" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070017 BG01095 BG01095 http://flybase.org/reports/FBgn0070017 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01095 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,viable,smell perception defective" FBgn0002952 nofF no object fixation F http://flybase.org/reports/FBgn0002952 - gene - - - nofF - - 11-Aug-17 DroID_v2017_08 - - - - - - "visual behavior defective,recessive" FBgn0000650 febA feeding behavior A http://flybase.org/reports/FBgn0000650 - gene - - - febA - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,behavior defective,recessive" FBgn0005456 l(1)v453 lethal (1) v453 http://flybase.org/reports/FBgn0005456 - gene - - - "l(1)453, l(1)v453" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262351 CG43049 - http://flybase.org/reports/FBgn0262351 protein_coding_gene - - - CG43049 - CG43049 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062692 EP1340 EP1340 http://flybase.org/reports/FBgn0062692 gene - - - "EP(X)1340, EP1340" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000506 dsx-c50F doublesex cognate 50F http://flybase.org/reports/FBgn0000506 - gene - - - "dsx-c50, dsx-c50F" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004024 ws waisted http://flybase.org/reports/FBgn0004024 - gene - - - ws - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,poor" "adult abdomen,wing" FBgn0003985 Vein-dominant Vein dominant http://flybase.org/reports/FBgn0003985 - gene - - - "Vein-dominant, Vn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,small body" "wing vein L4,wing" FBgn0042637 l(2)37Co lethal (2) 37Co http://flybase.net/reports/FBgn0042637.html gene unnamed 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0034614 CG9752 - http://flybase.org/reports/FBgn0034614 protein_coding_gene molecular_function ; GO:0003674 | no biological data available tRNA modification ; GO:0006400 | inferred from biological aspect of ancestor with PANTHER:PTN000481021 cellular_component ; GO:0005575 | no biological data available CG9752 "IPR019438:Potential Queuosine, Q, salvage protein family" CG9752 11-Aug-17 DroID_v2017_08 Drer\zgc:136564 - Cele\C11D2.4 Xtro\c9orf64 Mmus\2210016F16Rik Hsap\C9orf64 viable FBgn0024873 l(2)k03906b lethal (2) k03906b http://flybase.org/reports/FBgn0024873 - gene - - - "l(2)k03906b, l(2)k03906" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060953 l(3)S036401b lethal (3) S036401b http://flybase.org/reports/FBgn0060953 gene - - - "0364/01, l(3)S036401b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0025001 E(var)90 E(var)90 http://flybase.org/reports/FBgn0025001 - gene - - - "E-90, E(var)90" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013625 l(3)neo16 lethal (3) neo16 http://flybase.org/reports/FBgn0013625 - gene - - - l(3)neo16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011155 l(1)Q233 lethal (1) Q233 http://flybase.org/reports/FBgn0011155 FBgn0010210 gene - - - l(1)Q233 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032283 CG7296 - http://flybase.org/reports/FBgn0032283 protein_coding_gene - - - "BcDNA:RH68528, CG7296" - CG7296 11-Aug-17 DroID_v2017_08 - - - - - - "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" DRSC25754 K -0.036612709 -0.098074922 -0.055544649 -0.062876098 1.714408604 1.612904007 FBgn0010904 l(3)06906 lethal (3) 06906 http://flybase.org/reports/FBgn0010904 - gene - - - l(3)06906 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000324 clm clumpy marginals http://flybase.org/reports/FBgn0000324 - gene - - - clm - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,fertile,female,reduced,viable,male,visible,recessive,female fertile" "macrochaeta,dorsal double row,ventral triple row,wing sensillum" FBgn0051176 CG31176 - http://flybase.org/reports/FBgn0051176 protein_coding_gene - - - "CG6328, RE56061, EP(3)3662, EP3662, CG15495, CG31176" - CG31176 11-Aug-17 DroID_v2017_08 - - - - - - viable "intersegmental nerve,germline cell,male" FBgn0027949 msb1l msb1l http://flybase.org/reports/FBgn0027949 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "msh1l, CG10364, msb1l, Msb1l" - CG10364 11-Aug-17 DroID_v2017_08 Drer\si:ch211-69g19.2 - - - Mmus\Cdca3 Hsap\CDCA3 "viable,fertile,visible" trichogen cell FBgn0264940 CR44109 - http://flybase.org/reports/FBgn0264940 non_protein_coding_gene - - - CR44109 - CR44109 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029854 CG3566 - http://flybase.org/reports/FBgn0029854 protein_coding_gene - - mitochondrion ; GO:0005739 | inferred from direct assay "BcDNA:RH45308, CG3566" IPR001199:Cytochrome b5-like heme/steroid binding domain CG3566 11-Aug-17 DroID_v2017_08 "Drer\cyb5a, Drer\cyb5b" "Scer\OLE1, Scer\CYB2, Scer\CYB5, Scer\SCS7" "Cele\cytb-5.2, Cele\C25A1.5, Cele\D2023.1, Cele\cytb-5.1" "Xtro\cyb5b, Xtro\cyb5a" "Mmus\Cyb5a, Mmus\Cyb5b, Mmus\Fa2h, Mmus\Cyb5d1" "Hsap\FA2H, Hsap\CYB5B, Hsap\CYB5A" FBgn0052098 CG32098 - http://flybase.org/reports/FBgn0052098 protein_coding_gene - - - CG32098 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264543 CG43922 - http://flybase.org/reports/FBgn0264543 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43922 - CG43922 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038803 CG5191 - http://flybase.org/reports/FBgn0038803 protein_coding_gene - - - CG5191 IPR023631:Amidase signature domain CG5191 11-Aug-17 DroID_v2017_08 "Drer\faah2a, Drer\faah2b, Drer\faah" Scer\AMD2 "Cele\faah-6, Cele\Y53F4B.18, Cele\faah-1, Cele\faah-5, Cele\faah-3, Cele\faah-2" "Xtro\faah.2, Xtro\faah.1, Xtro\faah.3, Xtro\faah2" Mmus\Faah "Hsap\FAAH2, Hsap\FAAH" "viable,fertile" DRSC21559 E 1.492398459 1.173498091 1.868831465 -0.209582081 -0.085080681 0.85471704 FBgn0261603 M(2)60B Minute (2) 60B http://flybase.org/reports/FBgn0261603 gene - - - M(2)60B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038488 m-cup mann-cup http://flybase.org/reports/FBgn0038488 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:3649 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:3649 cellular_component ; GO:0005575 | no biological data available "m-cup, CG11896" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG11896 11-Aug-17 DroID_v2017_08 "Drer\fem1a, Drer\ankrd46b, Drer\fem1c, Drer\fem1b" - Cele\fem-1 "Xtro\fem1c, Xtro\fem1b" "Mmus\Fem1a, Mmus\Fem1b, Mmus\Fem1c, Mmus\4931440F15Rik, Mmus\Ankrd46" "Hsap\FEM1A, Hsap\LONRF2, Hsap\ANKRD46, Hsap\FEM1C, Hsap\FEM1B" viable FBgn0035431 CG14968 - http://flybase.org/reports/FBgn0035431 protein_coding_gene - - - "anon-WO0107627.3, anon-WO0107627.2, anon-WO0107627.1, CG14968" "IPR006020:PTB/PI domain, IPR011993:PH domain-like" CG14968 11-Aug-17 DroID_v2017_08 "Drer\ldlrap1b, Drer\ldlrap1a, Drer\si:dkey-71h2.2" - - Xtro\ldlrap1 Mmus\Ldlrap1 Hsap\LDLRAP1 viable FBgn0029180 E(Khc)ek7 E(Khc)ek7 http://flybase.org/reports/FBgn0029180 gene - - - E(Khc)ek7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021821 l(2)k16210 lethal (2) k16210 http://flybase.org/reports/FBgn0021821 - gene - - - l(2)k16210 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260360 GSd231 - http://flybase.org/reports/FBgn0260360 gene - - - GSd231 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0263264 com1 - http://flybase.org/reports/FBgn0263264 gene - gonad development ; GO:0008406 | inferred from mutant phenotype - com1 - - 11-Aug-17 DroID_v2017_08 - - - - - - gonad FBgn0085772 CR40743 - http://flybase.org/reports/FBgn0085772 rRNA_gene - - - CR40743 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262172 mir-307b mir-307b stem loop http://flybase.org/reports/FBgn0262172 miRNA_gene - - - "miR-307b, mir-307b, mir-307-as, CR42879, Dme-mir-307-as, miR-307-AS, miR-307, mir-307" - CR42879 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035309 CG15879 - http://flybase.org/reports/FBgn0035309 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15879 "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG15879 11-Aug-17 DroID_v2017_08 "Drer\bphl, Drer\serhl" - "Cele\K01A2.5, Cele\W01A11.1" "Xtro\serhl2, Xtro\serhl" Mmus\Serhl Hsap\SERHL2 viable FBgn0000733 fs(1)42 female sterile (1) 42 http://flybase.org/reports/FBgn0000733 - gene - - - fs(1)42 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,viable" "follicle cell,egg chamber,germarium,cystocyte" FBgn0051998 CG31998 - http://flybase.org/reports/FBgn0051998 protein_coding_gene - - - "CG11572, CG11578, CG31998" - CG31998 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011782 l(2)rL220 lethal (2) rL220 http://flybase.net/reports/FBgn0011782.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0001552 l(1)19Aa lethal (1) 19Aa http://flybase.org/reports/FBgn0001552 - gene - - - "EM18, l(1)EM18, l(1)19Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031178 CG10918 - http://flybase.org/reports/FBgn0031178 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model CG10918 - CG10918 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025759 l(3)93DFc lethal (3) 93DFc http://flybase.org/reports/FBgn0025759 - gene - - - l(3)93DFc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044109 E(rst)C383 E(rst)C383 http://flybase.org/reports/FBgn0044109 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C383, E(rst)C383" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065081 snmRNA:838 small non-messenger RNA 838 http://flybase.org/reports/FBgn0065081 non_protein_coding_gene - - - "Dm-838, CR33793, snmRNA:838" - CR33793 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015550 tap target of Poxn http://flybase.org/reports/FBgn0015550 "FBgn0010757, FBgn0019837" protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR032666 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype negative regulation of axon extension involved in axon guidance ; GO:0048843 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of Wnt signaling pathway, planar cell polarity pathway ; GO:2000095 | inferred from genetic interaction with dsh sensory organ development ; GO:0007423 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "CG7659, bps, l(3)01658, tap, Tap, bHLHc9, TAP" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR032666:Basic helix-loop-helix neural transcription factor TAP-like" CG7659 11-Aug-17 DroID_v2017_08 "Drer\neurod2, Drer\id2b, Drer\olig2, Drer\neurog1, Drer\id1, Drer\neurog3, Drer\id3, Drer\olig4, Drer\id2a, Drer\id4, Drer\hand2, Drer\neurod6b" - "Cele\cnd-1, Cele\hlh-31, Cele\ngn-1" "Xtro\olig4, Xtro\neurog3, Xtro\neurog1, Xtro\neurog2, Xtro\id3, Xtro\id4, Xtro\lyl1" "Mmus\Neurog1, Mmus\Neurog2, Mmus\Olig3, Mmus\Neurog3, Mmus\Olig1, Mmus\Neurod2, Mmus\Id1, Mmus\Id2, Mmus\Olig2, Mmus\Id4, Mmus\Bhlhe22, Mmus\Id3" "Hsap\ID4, Hsap\NEUROD2, Hsap\BHLHE22, Hsap\ID1, Hsap\OLIG1, Hsap\NEUROG3, Hsap\OLIG2, Hsap\BHLHE23, Hsap\MESP1, Hsap\ID2, Hsap\ID3, Hsap\NEUROG2, Hsap\NEUROG1" " embryonic stage | stage 10,11 , embryonic stage | stage 10-15 , embryonic stage , embryonic stage | stage 11 " " neuroblast NB4-1

, ventral nerve cord | restricted

, embryonic peripheral nervous system | restricted

, embryonic nervous system | restricted

, embryonic ganglion mother cell

, neuroblast

" embryonic stage v'es2 neuron

"lethal,recessive,tarsal response defective,heat sensitive,viable" DRSC11402 E -0.184161504 0.776995246 0.937501796 -1.548536604 -0.846422776 0.935052817 FBgn0034277 OstDelta Oligosaccharide transferase Delta subunit http://flybase.org/reports/FBgn0034277 protein_coding_gene dolichyl-diphosphooligosaccharide-protein glycotransferase activity ; GO:0004579 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000291016 encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype protein N-linked glycosylation ; GO:0006487 | inferred from biological aspect of ancestor with PANTHER:PTN000291016 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008814 oligosaccharyltransferase complex ; GO:0008250 | inferred from biological aspect of ancestor with PANTHER:PTN000291016 endomembrane system ; GO:0012505 | inferred from direct assay "OstDelta, CG6370, OST" IPR008814:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 CG6370 11-Aug-17 DroID_v2017_08 Drer\rpn2 Scer\SWP1 Cele\ostd-1 Xtro\rpn2 Mmus\Rpn2 Hsap\RPN2 "viable,immune response defective" FBgn0284250 Oaz O/E-associated zinc finger protein http://flybase.org/reports/FBgn0284250 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype" - "Oaz, l(2)03563, CG42702, dmOAZ, CG17390, CG17388, CG17389, Dm_2R:42259, oaz" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG42702 11-Aug-17 DroID_v2017_08 "Drer\znf521, Drer\ikzf1, Drer\si:dkey-166n8.9, Drer\si:ch211-216l23.1, Drer\si:ch73-112l6.1, Drer\LOC100537687, Drer\si:zfos-1425h8.1, Drer\rest, Drer\ikzf5" - "Cele\spr-4, Cele\Y48G8AL.10" "Xtro\ikzf2, Xtro\ikzf4, Xtro\ikzf3, Xtro\znf423, Xtro\ikzf1" "Mmus\2610008E11Rik, Mmus\Ikzf3, Mmus\Ikzf2, Mmus\Zfp423, Mmus\Ikzf4, Mmus\Ikzf5, Mmus\Zfp715, Mmus\Zfp663, Mmus\Zfp64, Mmus\Ikzf1, Mmus\Zfp521, Mmus\Zfp708" "Hsap\IKZF1, Hsap\IKZF4, Hsap\IKZF5, Hsap\IKZF2, Hsap\IKZF3, Hsap\ZNF423, Hsap\ZNF521" "lethal,recessive" FBgn0259479 EP-553 - http://flybase.org/reports/FBgn0259479 gene - - - EP-553 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,wing margin,chaeta,ectopic" FBgn0021966 l(2)k10103 lethal (2) k10103 http://flybase.org/reports/FBgn0021966 - gene - - - l(2)k10103 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030479 Rbp1-like Rbp1-like http://flybase.org/reports/FBgn0030479 protein_coding_gene mRNA binding ; GO:0003729 | inferred from direct assay "regulation of mRNA 3'-end processing ; GO:0031440 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from mutant phenotype regulation of transcriptional start site selection at RNA polymerase II promoter ; GO:0001178 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "RBP1-like, CG1987, i159, BEST:HL02433, BcDNA:RE47308, Rbp1-like, Rbp1L" IPR000504:RNA recognition motif domain CG1987 11-Aug-17 DroID_v2017_08 "Drer\srsf3b, Drer\srsf7a, Drer\srsf3a, Drer\srsf7b" Scer\NPL3 "Cele\Y57G11A.5, Cele\rsp-6" "Xtro\srsf3, Xtro\srsf7" "Mmus\Srsf7, Mmus\Srsf3" "Hsap\SRSF7, Hsap\SRSF3" "viable,fertile" FBgn0050169 Brca2 "BRCA2, DNA repair associated" http://flybase.org/reports/FBgn0050169 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A8JNV5 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q27297 meiotic recombination checkpoint ; GO:0051598 | inferred from mutant phenotype inferred from genetic interaction with okr inferred from genetic interaction with spn-A inferred from genetic interaction with spn-D meiotic DNA repair synthesis involved in reciprocal meiotic recombination ; GO:0010778 | inferred from mutant phenotype response to camptothecin ; GO:1901563 | inferred from mutant phenotype DNA synthesis involved in double-strand break repair via homologous recombination ; GO:0043150 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from direct assay double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG13584, CG13583, BcDNA:SD25109, brca2, Dmbrca2, Brca2, CG30169, 30169, dmbrca2, BRCA2" "IPR002093:BRCA2 repeat, IPR015525:Breast cancer type 2 susceptibility protein" CG30169 11-Aug-17 DroID_v2017_08 Drer\brca2 - - - Mmus\Brca2 Hsap\BRCA2 "chemical sensitive,female sterile,viable,radiation sensitive,DNA repair defective,recessive" "karyosome,dorsal appendage,maternal effect" FBgn0024854 ltwt lightweight http://flybase.org/reports/FBgn0024854 - gene - - - ltwt - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0050362 boly borrelly http://flybase.org/reports/FBgn0050362 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG2149, NEST:bs34d07, boly, CG30362" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG30362 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051242 tRNA:Gly-TCC-1-3 transfer RNA:Glycine-TCC 1-3 http://flybase.org/reports/FBgn0051242 tRNA_gene GGA codon-amino acid adaptor activity ; GO:0033463 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033463 cytosol ; GO:0005829 | inferred by curator from GO:0033463 "AE002708.trna18-GlyTCC, tRNA[Gly][[GGA]], tRNA:gly:90DE, tRNA:G:90DE, tRNA:G:TCC:AE002708-a, CR31242, chr3R.trna24-GlyTCC, tRNA-Gly-TCC-1-3, tRNA:Gly-TCC-1-3, tRNA:CR31242, GGA" - CR31242 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010309 pigeon pigeon http://flybase.org/reports/FBgn0010309 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lio, pio, CG10739, pigeon" "IPR028010:Gamma-secretase-activating protein, C-terminal domain, IPR026172:Gamma-secretase-activating protein family" CG10739 11-Aug-17 DroID_v2017_08 Drer\gsap - - - Mmus\Gsap Hsap\GSAP embryonic stage&&pupal stage&&adult stage "memory defective,learning defective,neuroanatomy defective,viable,recessive" synapse FBgn0019660 roX2 RNA on the X 2 http://flybase.org/reports/FBgn0019660 FBgn0052665 non_protein_coding_gene RNA stem-loop binding ; GO:0035613 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with mle dosage compensation ; GO:0007549 | inferred from direct assay dosage compensation ; GO:0007549 | traceable author statement dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome ; GO:0016457 | non-traceable author statement dosage compensation by hyperactivation of X chromosome ; GO:0009047 | traceable author statement negative regulation of chromatin silencing ; GO:0031936 | inferred from genetic interaction with roX1 "X chromosome ; GO:0000805 | traceable author statement X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | traceable author statement X chromosome ; GO:0000805 | non-traceable author statement MSL complex ; GO:0072487 | inferred from direct assay" "roX2, roX, rox2, CR32665, RoX2" - CR32665 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male " optic lobe neuron

, cell body &&of mushroom body

, pupal/adult digestive system

, cell body &&of adult brain

, neuron &&of antennal segment 3

, interneuron &&of antennal lobe

, thoracico-abdominal ganglion

, photoreceptor cell

" FBgn0266833 CR45295 - http://flybase.org/reports/FBgn0266833 non_protein_coding_gene - - - CR45295 - CR45295 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262393 mir-33 mir-33 stem loop http://flybase.org/reports/FBgn0262393 miRNA_gene - - - "miR-33, mir-33, dme-mir-33, 33, MIR-33, CR42928, CR33569, miR33, dme-miR-33" - CR42928 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001859 l(1)TW4 lethal (1) TW4 http://flybase.org/reports/FBgn0001859 - gene - - - l(1)TW4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,cold sensitive,female fertile" metathoracic leg FBgn0060849 l(3)S048606a lethal (3) S048606a http://flybase.org/reports/FBgn0060849 gene - - - "0486/06, l(3)S048606a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264273 Sema2b Semaphorin 2b http://flybase.org/reports/FBgn0264273 protein_coding_gene - dendrite guidance ; GO:0070983 | inferred from genetic interaction with Sema2a synaptic target attraction ; GO:0016200 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok olfactory bulb axon guidance ; GO:0071678 | inferred from mutant phenotype dendrite self-avoidance ; GO:0070593 | inferred from mutant phenotype regulation of cell-matrix adhesion ; GO:0001952 | inferred from mutant phenotype - "Sema-2b, sema-2b, Sema2b, CG33960, SemaIIB, CG4383, CG30322, sema2b" "IPR001627:Sema domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR027231:Semaphorin, IPR013783:Immunoglobulin-like fold" CG33960 11-Aug-17 DroID_v2017_08 "Drer\sema7a, Drer\sema5a, Drer\sema3bl, Drer\si:ch211-168n16.1, Drer\sema3h, Drer\sema6e, Drer\sema4ba, Drer\sema3ga, Drer\sema4ab, Drer\sema6a, Drer\sema3gb, Drer\sema3aa, Drer\si:ch211-129c21.1, Drer\sema3c, Drer\sema6d, Drer\sema5ba, Drer\sema5bb, Drer\sema3ab, Drer\sema4e, Drer\sema3d, Drer\sema6bb, Drer\sema4c, Drer\sema3fb, Drer\LOC798168, Drer\sema4d, Drer\sema6dl, Drer\sema4gb, Drer\sema3e, Drer\sema3b, Drer\rttn, Drer\sema4ga, Drer\si:dkey-49n23.1, Drer\si:ch211-113g11.6, Drer\sema3fa" - "Cele\F23H12.5, Cele\smp-1, Cele\mab-20, Cele\smp-2" "Xtro\sema4a, Xtro\sema4g, Xtro\sema3d, Xtro\sema6b, Xtro\sema4c, Xtro\sema6d, Xtro\sema3b, Xtro\sema6a, Xtro\sema5b, Xtro\sema3f, Xtro\sema3c, Xtro\sema3a, Xtro\sema4d, Xtro\sema4b" "Mmus\Sema7a, Mmus\Sema3c, Mmus\Sema3f, Mmus\Sema6c, Mmus\Sema6d, Mmus\Sema3a, Mmus\Sema6b, Mmus\Sema4a, Mmus\Sema4b, Mmus\Sema6a, Mmus\Sema5b, Mmus\Sema4c, Mmus\Sema4f, Mmus\Sema5a, Mmus\Sema4d, Mmus\Sspo, Mmus\Sema4g, Mmus\Sema3b, Mmus\Sema3g, Mmus\Sema3d, Mmus\Sema3e" "Hsap\SEMA4C, Hsap\SEMA4A, Hsap\SEMA5B, Hsap\SEMA4G, Hsap\SEMA5A, Hsap\SEMA3B, Hsap\SEMA7A, Hsap\SEMA3C, Hsap\SEMA6B, Hsap\SEMA3F, Hsap\SEMA3G, Hsap\SEMA3E, Hsap\SEMA6C, Hsap\SEMA4D, Hsap\SEMA6D, Hsap\SEMA4B, Hsap\SEMA3D, Hsap\SEMA4F, Hsap\SEMA6A, Hsap\SEMA3A" FBgn0024850 mus114 mus114 http://flybase.org/reports/FBgn0024850 - gene - - - mus114 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0002041 l(2)37De lethal (2) 37De http://flybase.org/reports/FBgn0002041 - gene - - - "OE30, l(2)OE70, l(2)OE30, l(2)37De" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive,cold sensitive" "eye,wing" FBgn0037179 CG14453 - http://flybase.org/reports/FBgn0037179 protein_coding_gene - - - "BcDNA:RE13473, CG14453" - CG14453 11-Aug-17 DroID_v2017_08 Drer\si:ch211-22i13.2 - - - - - DRSC11710 I -2.074409373 0.111902553 -0.899454941 0.863838407 -0.382998361 -0.571448675 FBgn0004979 bal bandy legged http://flybase.org/reports/FBgn0004979 - gene - - - bal - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,fertile,locomotor behavior defective" leg FBgn0038018 Tim17a1 Tim17a1 http://flybase.org/reports/FBgn0038018 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:Q99595 protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000050380 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q99595 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q99595 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 "CG10090, Tim17a1, Tim17 a1" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG10090 11-Aug-17 DroID_v2017_08 "Drer\timm17a, Drer\timm17b" Scer\TIM17 "Cele\D2096.1, Cele\E04A4.5" Xtro\timm17a "Mmus\Timm17a, Mmus\Timm17b" "Hsap\TIMM17B, Hsap\TIMM17A" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0039438 TwdlO TweedleO http://flybase.org/reports/FBgn0039438 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlO, CG6452" IPR004145:Domain of unknown function DUF243 CG6452 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC16043 IK 2.770013037 0.149993388 -0.275530227 0.148699782 -0.48653355 1.845498599 FBgn0261003 Qajjem Qajjem http://flybase.org/reports/FBgn0261003 gene - - - "Qajjem, AGAR-211" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0010686 l(2)s2978 lethal (2) s2978 http://flybase.net/reports/FBgn0010686.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive,partially lethal - majority die" FBgn0082618 S(CycE[JP])59S9 S(CycE[JP])59S9 http://flybase.org/reports/FBgn0082618 gene - - - "59S9, S(CycE[JP])59S9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0260359 GSd458 - http://flybase.org/reports/FBgn0260359 gene - - - GSd458 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "longitudinal connective,ventral nerve cord" FBgn0011272 RpL13 Ribosomal protein L13 http://flybase.org/reports/FBgn0011272 "FBgn0014460, FBgn0025260" protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000197497 "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001380, InterPro:IPR018256 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement" ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "Dmbbc1, Rpl13, bbc1, rpL13, anon-EST:fe1D1, CG4651, Bbc1, RpL13, L13, Rp L13" "IPR018256:Ribosomal protein L13e, conserved site, IPR001380:Ribosomal protein L13e, IPR034295:Ribosomal protein L13, eukaryotic" CG4651 11-Aug-17 DroID_v2017_08 Drer\rpl13 "Scer\RPL13A, Scer\RPL13B" Cele\rpl-13 Xtro\rpl13 Mmus\Rpl13 Hsap\RPL13 embryonic stage -- adult stage DRSC03416 IEK 0.002462202 -1.757895438 -1.21735038 -4.387297988 1.649225565 6.38262367 FBgn0001533 l(1)14Aa lethal (1) 14Aa http://flybase.org/reports/FBgn0001533 - gene - - - "h26a, l(1)14Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005202 l(3)blo-l lethal bloated larvae http://flybase.org/reports/FBgn0005202 - gene - - - l(3)blo-l - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" imaginal disc FBgn0002424 l(3)F23 lethal (3) F23 http://flybase.org/reports/FBgn0002424 - gene - - - "l(3)23, l(3)F23" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033787 CG13321 - http://flybase.org/reports/FBgn0033787 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG13321 "IPR006616:DM9 repeat, IPR024518:Domain of unknown function DUF3421" CG13321 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0040900 CG17777 - http://flybase.org/reports/FBgn0040900 protein_coding_gene - - - CG17777 - CG17777 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039298 to takeout http://flybase.org/reports/FBgn0039298 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mating behavior ; GO:0007617 | traceable author statement feeding behavior ; GO:0007631 | non-traceable author statement feeding behavior ; GO:0007631 | traceable author statement response to starvation ; GO:0042594 | traceable author statement rhythmic behavior ; GO:0007622 | traceable author statement circadian rhythm ; GO:0007623 | inferred from expression pattern male courtship behavior ; GO:0008049 | inferred from mutant phenotype inferred from genetic interaction with fru adult feeding behavior ; GO:0008343 | inferred from mutant phenotype behavioral response to starvation ; GO:0042595 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | traceable author statement circadian rhythm ; GO:0007623 | non-traceable author statement extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG11853, CT33074, to, To, Takeout" IPR010562:Haemolymph juvenile hormone binding CG11853 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,circadian rhythm defective,partially lethal - majority live,feeding behavior defective" DRSC17086 E -0.886431929 0.010562298 -1.143400024 3.411191939 0.12695303 0.532644545 FBgn0087021 Spc25 Spc25 http://flybase.org/reports/FBgn0087021 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q960D9 inferred from physical interaction with UniProtKB:Q9VYB1 meiotic metaphase plate congression ; GO:0051311 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype Ndc80 complex ; GO:0031262 | inferred from sequence or structural similarity with HGNC:24031 Ndc80 complex ; GO:0031262 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay "cal2, Spc25, CG7242, l(3)S3, S3, l(3)A46-1, l(3)A34-1, l(3)87Da, BcDNA:LD37196, l(3)c00064, Mitch, dmSpc25R, Cal2, spc25" - CG7242 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053539 tRNA:Trp-CCA-2-5 transfer RNA:Tryptophan-CCA 2-5 http://flybase.org/reports/FBgn0053539 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "CR33539, AE002575.trna2-TrpCCA, tRNA:W:CCA:AE002575-b, chr2R.trna46-TrpCCA, tRNA-Trp-CCA-2-5, tRNA:Trp-CCA-2-5, tRNA:CR33539, UGG" - CR33539 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024650 l(2)k09208 lethal (2) k09208 http://flybase.org/reports/FBgn0024650 - gene - - - "92/8, l(2)k09208" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065733 l(2)SH0549 lethal (2) SH0549 http://flybase.org/reports/FBgn0065733 gene - - - "l(2)SH0549, l(2)SH2 0549" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043595 E(ro[DOM])1801 E(ro[DOM])1801 http://flybase.org/reports/FBgn0043595 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available E(ro[DOM])1801 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030120 CG17440 - http://flybase.org/reports/FBgn0030120 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 - - CG17440 "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17440 11-Aug-17 DroID_v2017_08 "Drer\cxxc1a, Drer\cxxc1b" "Scer\SPP1, Scer\SET3, Scer\CTI6" "Cele\set-32, Cele\set-22, Cele\set-26, Cele\cfp-1, Cele\set-9" Xtro\cxxc1 "Mmus\Kmt2e, Mmus\Cxxc1" Hsap\CXXC1 FBgn0062651 EP382 EP382 http://flybase.org/reports/FBgn0062651 gene - - - "EP(X)0382, EP382" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011578 ded depleted http://flybase.org/reports/FBgn0011578 - gene - peripheral nervous system development ; GO:0007422 | traceable author statement - ded - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "external sensory organ,chordotonal organ,multidendritic neuron" FBgn0036591 CG13050 - http://flybase.org/reports/FBgn0036591 protein_coding_gene - - - CG13050 - CG13050 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC09931 K 0.363376552 1.170282247 1.288011069 0.153139876 0.739703488 1.58104468 FBgn0001824 l(1)trs lethal (1) tracheae stretched http://flybase.org/reports/FBgn0001824 - gene - - - "l(1)ts, l(1)trs" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" embryonic/larval tracheal system FBgn0085432 pan pangolin http://flybase.org/reports/FBgn0085432 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay kinase binding ; GO:0019900 | inferred from physical interaction with Hipk protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P16371 inferred from physical interaction with UniProtKB:P18824 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from direct assay transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000042967 beta-catenin binding ; GO:0008013 | inferred from biological aspect of ancestor with PANTHER:PTN000042967 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with Coop" "spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype mesodermal cell fate determination ; GO:0007500 | traceable author statement heart development ; GO:0007507 | traceable author statement canonical Wnt signaling pathway ; GO:0060070 | inferred from biological aspect of ancestor with PANTHER:PTN000042967 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype regulation of stem cell proliferation ; GO:0072091 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from sequence or structural similarity with UniProtKB:P91943 regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay embryonic pattern specification ; GO:0009880 | inferred from sequence or structural similarity with UniProtKB:P91943 positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | non-traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from sequence or structural similarity with UniProtKB:P91943 regulation of Wnt signaling pathway ; GO:0030111 | inferred from sequence or structural similarity with UniProtKB:P91943 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from expression pattern embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from sequence or structural similarity with UniProtKB:P91943 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with Coop "pan, dTcf, CG34403, CG32005, TCF, Tcf, Lef, Pan, dTCF, LEF-1, Tcf/LEF, LEF/TCF, LEF/TCF-1, DTCF, IA5, Tcf-1, l(4)13, DTcf, lef1, TCF/LEF1, TCF/LEF, tcf, l(4)102ABb, CG17964, PAN, LEF1/TCF, LEF1, Lef1, pan.dTCF, d-TCF, Dm Pan, TCF/Pan" "IPR013558:CTNNB1 binding, N-teminal, IPR009071:High mobility group box domain, IPR024940:Transcription factor TCF/LEF, IPR027397:Catenin binding domain" CG34403 11-Aug-17 DroID_v2017_08 "Drer\tcf7, Drer\tcf7l2, Drer\tcf7l1b, Drer\tcf7l1a, Drer\lef1" Scer\ABF2 Cele\pop-1 "Xtro\lef1, Xtro\tcf7l2, Xtro\tcf7, Xtro\tcf7l1" "Mmus\Tcf7l1, Mmus\Tcf7l2, Mmus\Tcf7, Mmus\Lef1" "Hsap\TCF7L2, Hsap\LEF1, Hsap\TCF7, Hsap\TCF7L1" " embryonic stage | stage 13 , embryonic stage | early , embryonic stage | 0-2hr , embryonic stage | stage 7 , embryonic stage " " procephalic segment

,

ubiquitous , visceral mesoderm

" FBgn0000239 bur burgundy http://flybase.org/reports/FBgn0000239 "FBgn0010666, FBgn0032928, FBgn0062173, FBgn0062180" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001674, InterPro:IPR004739, InterPro:IPR025777 pyrophosphatase activity ; GO:0016462 | inferred from electronic annotation with InterPro:IPR025777 GMP synthase (glutamine-hydrolyzing) activity ; GO:0003922 | inferred from biological aspect of ancestor with PANTHER:PTN000229987 deubiquitinase activator activity ; GO:0035800 | inferred from direct assay GMP synthase activity ; GO:0003921 | inferred from biological aspect of ancestor with PANTHER:PTN000229987" histone deubiquitination ; GO:0016578 | inferred from direct assay axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of ubiquitin-specific protease activity ; GO:2000152 | inferred from direct assay GMP biosynthetic process ; GO:0006177 | inferred from biological aspect of ancestor with PANTHER:PTN000229987 polytene chromosome ; GO:0005700 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Usp7 "GMPS, CG9242, l(2)10523, P174, ES2-2, gua2, anon-WO0118547.204, anon-WO0118547.193, bur, Gmps" "IPR025777:GMP synthetase ATP pyrophosphatase domain, IPR001674:GMP synthase, C-terminal, IPR004739:GMP synthase, glutamine amidotransferase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR017926:Glutamine amidotransferase, IPR029062:Class I glutamine amidotransferase-like, IPR022310:NAD/GMP synthase" CG9242 11-Aug-17 DroID_v2017_08 Drer\gmps Scer\GUA1 Cele\gmps-1 Xtro\gmps Mmus\Gmps Hsap\GMPS "lethal,recessive,neuroanatomy defective,visible,viable,eye color defective,female fertile,good,male fertile,partially,lethal - all die before end of pupal stage,some die during pupal stage,auxotroph" "lamina,medulla,photoreceptor cell R7 & growth cone,photoreceptor cell R8 & growth cone,photoreceptor cell & axon,photoreceptor cell & axon | somatic clone | cell autonomous,pigment cell" FBgn0065361 l(2)SH1744 lethal (2) SH1744 http://flybase.org/reports/FBgn0065361 gene - - - "l(2)SH1744, l(2)SH2 1744" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010462 l(2)00329 lethal (2) 00329 http://flybase.org/reports/FBgn0010462 - gene - - - l(2)00329 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260065 2L3908 - http://flybase.org/reports/FBgn0260065 gene - - - 2L3908 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0019918 TrlBR Trithorax-like Binding Region http://flybase.org/reports/FBgn0019918 - engineered_region - - - TrlBR - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010088 Su(Dl)F116 Suppressor of Delta F116 http://flybase.org/reports/FBgn0010088 - gene - - - Su(Dl)F116 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001793 l(1)Mb24 lethal (1) Mb24 http://flybase.org/reports/FBgn0001793 - gene - - - l(1)Mb24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "macrochaeta,wing hair" FBgn0029940 CG1958 - http://flybase.org/reports/FBgn0029940 protein_coding_gene - - - CG1958 - CG1958 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034826 CG13544 - http://flybase.org/reports/FBgn0034826 protein_coding_gene myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis - - CG13544 "IPR000048:IQ motif, EF-hand binding site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG13544 11-Aug-17 DroID_v2017_08 Drer\spata17 - Cele\aspm-1 - "Mmus\Aspm, Mmus\Spata17" "Hsap\SPATA17, Hsap\ASPM" "partially lethal - majority die,some die during pupal stage" FBgn0266812 CR45274 - http://flybase.org/reports/FBgn0266812 non_protein_coding_gene - - - CR45274 - CR45274 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051885 tRNA:Thr-AGT-1-1 transfer RNA:Threonine-AGT 1-1 http://flybase.org/reports/FBgn0051885 tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "AE002690.trna20-ThrAGT, tRNA:T:AGT:AE002690, CR31885, tRNA[[Thr]], chr2L.trna29-ThrAGT, tRNA-Thr-AGT-1-1, tRNA:Thr-AGT-1-1, tRNA:CR31885, ACU" - CR31885 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264802 l(3)64Ab lethal (3) 64Ab http://flybase.org/reports/FBgn0264802 gene - - - "l(3)64Ab, l(3)S137212, l(3)SH19, l(3)SH15, 1372/12" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063496 GstE4 Glutathione S transferase E4 http://flybase.org/reports/FBgn0063496 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG17525, DmGSTE4, GstE4, GSTE4, gste4" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17525 11-Aug-17 DroID_v2017_08 "Drer\gstt1a, Drer\gstt1b, Drer\mars, Drer\eef1g, Drer\gstr, Drer\eef1e1, Drer\vars, Drer\gstt2" "Scer\YGR201C, Scer\GTT2, Scer\GTT1, Scer\TEF4, Scer\URE2, Scer\CAM1" "Cele\gst-29, Cele\gst-21" "Xtro\gstt1, Xtro\eef1e1, Xtro\eef1g" "Mmus\Eef1e1, Mmus\Gstt1, Mmus\Mars, Mmus\Eef1g, Mmus\Gstt3, Mmus\Gstt4, Mmus\Vars, Mmus\Gstt2" "Hsap\GSTT2, Hsap\EEF1G, Hsap\GSTT1, Hsap\GSTT2B, Hsap\MARS, Hsap\VARS, Hsap\EEF1E1" viable FBgn0038781 CG10883 - http://flybase.org/reports/FBgn0038781 protein_coding_gene - - - CG10883 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038242 CG14852 - http://flybase.org/reports/FBgn0038242 protein_coding_gene - - - CG14852 - CG14852 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0263000 CG43308 - http://flybase.org/reports/FBgn0263000 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43308 - CG43308 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025154 ms(2)A2 ms(2)A2 http://flybase.org/reports/FBgn0025154 - gene - - - ms(2)A2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0022324 l(1)B10.2 lethal (1) B10.2 http://flybase.org/reports/FBgn0022324 - gene - - - l(1)B10.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083271 E(smoDN)2619 Enhancer of smoDN 2619 http://flybase.org/reports/FBgn0083271 gene - - - E(smoDN)2619 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038063 Octbeta2R Octopamine beta2 receptor http://flybase.org/reports/FBgn0038063 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR004827 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827 G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity octopamine receptor activity ; GO:0004989 | inferred from sequence or structural similarity with UniProtKB:Q9VCZ3 inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR004827 ovulation ; GO:0030728 | inferred from mutant phenotype positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010579 | inferred from direct assay positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity fertilization ; GO:0009566 | inferred from mutant phenotype adenylate cyclase-activating G-protein coupled receptor signaling pathway ; GO:0007189 | inferred from sequence or structural similarity with UniProtKB:Q9VCZ3" integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG6989, DmOctbeta2R, CG33976, DmCG6989, anon-WO0170980.185, anon-WO0170980.184, CG18553, Octbeta2R, OctBeta2, OctB2R, Octbeta2r, Dm_3R:45121, octbeta2R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR004827:Basic-leucine zipper domain, IPR017452:GPCR, rhodopsin-like, 7TM" CG33976 11-Aug-17 DroID_v2017_08 "Drer\htr4, Drer\taar10c, Drer\taar14b, Drer\adrb2a, Drer\taar18g, Drer\taar12j, Drer\taar14f, Drer\taar20i, Drer\taar16f, Drer\taar20o, Drer\LOC567498, Drer\taar12b, Drer\LOC563567, Drer\si:ch211-139n6.11, Drer\taar13e, Drer\drd1b, Drer\taar10, Drer\taar20h, Drer\taar20b, Drer\taar20r, Drer\drd7, Drer\taar12a, Drer\taar10d, Drer\taar12h, Drer\taar13d, Drer\si:dkey-247m21.3, Drer\drd1a, Drer\taar14g, Drer\drd6b, Drer\taar19g, Drer\si:ch211-238p8.35, Drer\taar19o, Drer\taar19r, Drer\taar20j, Drer\taar20c1, Drer\taar19k, Drer\taar19c, Drer\taar19d, Drer\taar14l, Drer\taar18b, Drer\taar20a, Drer\taar14e, Drer\adra1ab, Drer\taar20u, Drer\taar12i, Drer\taar14i, Drer\taar14h, Drer\taar12e, Drer\taar19p, Drer\taar14a, Drer\taar18e, Drer\taar12f, Drer\taar20w, Drer\taar20l, Drer\zgc:153137, Drer\taar19b, Drer\taar20n, Drer\adrb2b, Drer\adrb3b, Drer\taar11, Drer\taar1b, Drer\taar19e, Drer\taar14j, Drer\taar20t, Drer\taar18a, Drer\taar18c, Drer\taar20x, Drer\taar64, Drer\taar12g, Drer\si:dkey-246e3.4, Drer\taar12c, Drer\taar12m, Drer\taar13c, Drer\taar20q, Drer\taar14d, Drer\taar10a, Drer\taar20c, Drer\taar15, Drer\taar13b, Drer\taar19m, Drer\LOC100149223, Drer\taar10b" - "Cele\ckr-2, Cele\ser-5, Cele\dop-1, Cele\F59D12.1" "Xtro\htr4, Xtro\drd5, Xtro\adrb2, Xtro\drd1c, Xtro\drd1" "Mmus\Drd5, Mmus\Taar9, Mmus\Taar3, Mmus\Taar8b, Mmus\Htr4, Mmus\Taar8c, Mmus\Taar7a, Mmus\Taar7e, Mmus\Taar5, Mmus\Taar6, Mmus\Adrb2, Mmus\Taar8a, Mmus\Taar2, Mmus\Taar7b, Mmus\Drd1, Mmus\Taar7f, Mmus\Taar7d, Mmus\Taar4, Mmus\Taar1" "Hsap\TAAR2, Hsap\TAAR6, Hsap\TAAR8, Hsap\HTR4, Hsap\TAAR1, Hsap\DRD1, Hsap\DRD5, Hsap\TAAR5, Hsap\ADRB2, Hsap\TAAR9" "viable,fertile,neurophysiology defective,starvation stress response defective,neuroanatomy defective,recessive,locomotor behavior defective,sleep defective" "multidendritic neuron,type I bouton,embryonic/larval neuromuscular junction,type II bouton,type II bouton | third instar larval stage,type I bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" DRSC15350 EK -1.345375621 -1.209757201 -1.513269668 -1.57090047 -0.52333574 -1.666490362 FBgn0025156 ms(2)A11 ms(2)A11 http://flybase.org/reports/FBgn0025156 - gene - - - ms(2)A11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0040328 EY3-3 EY3-3 http://flybase.org/reports/FBgn0040328 gene - - - EY3-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265352 Myo31DF::Myo61F - http://flybase.org/reports/FBgn0265352 engineered_fusion_gene - - - Myo31DF::Myo61F - - 11-Aug-17 DroID_v2017_08 - - - - - - axis specification defective "embryonic foregut,embryonic/larval midgut,embryonic hindgut" FBgn0061144 l(3)S000417c lethal (3) S000417c http://flybase.org/reports/FBgn0061144 gene - - - "0004/17, l(3)S000417c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050293 Cht12 Chitinase 12 http://flybase.org/reports/FBgn0050293 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 "chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "NEST:bs28h08, NEST:bs33a06, NEST:bs09g08, BcDNA:AT18578, Cht12, CG30293, DmCht12" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR002557:Chitin binding domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG30293 11-Aug-17 DroID_v2017_08 "Drer\srl, Drer\chia.1, Drer\chia.2, Drer\si:ch211-226m16.2, Drer\ovgp1, Drer\chia.5" Scer\CTS2 "Cele\chil-3, Cele\chil-15, Cele\chil-26, Cele\chil-9, Cele\chil-23, Cele\chil-20, Cele\chil-2, Cele\chil-6, Cele\T19H5.6, Cele\chil-11, Cele\chil-4, Cele\cht-1, Cele\chil-13, Cele\chil-7, Cele\cht-2, Cele\chil-24, Cele\lmd-4, Cele\chil-12, Cele\chil-19, Cele\chil-17, Cele\chil-22, Cele\chil-8, Cele\chil-1, Cele\chil-16, Cele\chil-5, Cele\R09D1.14, Cele\chil-21, Cele\chil-18, Cele\lmd-5, Cele\chil-25, Cele\cht-4" "Xtro\chit1, Xtro\chia, Xtro\LOC548945, Xtro\srl, Xtro\ctbs" "Mmus\Chia1, Mmus\Chil3, Mmus\Ctbs, Mmus\Chil4, Mmus\Chit1, Mmus\Chil6, Mmus\Ovgp1, Mmus\Chil1, Mmus\Chil5, Mmus\Srl" "Hsap\CHI3L1, Hsap\SRL, Hsap\CHIA, Hsap\CHIT1, Hsap\OVGP1, Hsap\CHI3L2" viable FBgn0039736 CG7912 - http://flybase.org/reports/FBgn0039736 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 CG7912 "IPR002645:STAS domain, IPR011547:SLC26A/SulP transporter domain, IPR001902:SLC26A/SulP transporter" CG7912 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-117c9.2, Drer\slc26a11, Drer\slc26a3.1, Drer\slc26a6l, Drer\slc26a1, Drer\slc26a3.2, Drer\slc26a5, Drer\slc26a4, Drer\slc26a2, Drer\slc26a6, Drer\slc26a10" "Scer\SUL2, Scer\YGR125W, Scer\YPR003C, Scer\SUL1" "Cele\sulp-1, Cele\sulp-7, Cele\sulp-8, Cele\sulp-3, Cele\sulp-4, Cele\sulp-5, Cele\sulp-2, Cele\sulp-6" "Xtro\slc26a11, Xtro\slc26a6, Xtro\slc26a5, Xtro\slc26a1, Xtro\slc26a4, Xtro\slc26a7, Xtro\slc26a9, Xtro\slc26a2, Xtro\slc26a10" "Mmus\Slc26a9, Mmus\Slc26a7, Mmus\Slc26a11, Mmus\Slc26a3, Mmus\Slc26a1, Mmus\Slc26a4, Mmus\Slc26a6, Mmus\Slc26a5, Mmus\Slc26a2, Mmus\Slc26a8, Mmus\Slc26a10" "Hsap\SLC26A2, Hsap\SLC26A5, Hsap\SLC26A10, Hsap\SLC26A11, Hsap\SLC26A4, Hsap\SLC26A7, Hsap\SLC26A1, Hsap\SLC26A8, Hsap\SLC26A3, Hsap\SLC26A6, Hsap\SLC26A9" viable DRSC16343 I -0.465041155 3.983932896 -0.625800513 0.037061871 -0.689923135 0.530643942 FBgn0061360 CG33672 - http://flybase.org/reports/FBgn0061360 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG33009, CG8810, CG16804a, CG16804, CG33009-ORFA, CG33672, Dromel_CG33672_FBtr0091651_uORF, CG33009ORFA" IPR002634:BolA protein CG33672 11-Aug-17 DroID_v2017_08 "Drer\alg6, Drer\bola3, Drer\zgc:112271" "Scer\AIM1, Scer\FRA2, Scer\YAL044W-A" "Cele\C08B11.8, Cele\K11H12.1, Cele\T12D8.10, Cele\Y105E8A.11" "Xtro\bola3, Xtro\alg6, Xtro\bola2" "Mmus\Bola3, Mmus\Bola2, Mmus\Bola1, Mmus\Alg6" "Hsap\LOC107984053, Hsap\BOLA1, Hsap\BOLA2B, Hsap\BOLA3, Hsap\BOLA2, Hsap\BOLA2-SMG1P6" FBgn0033783 CG17019 - http://flybase.org/reports/FBgn0033783 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17019 "IPR001841:Zinc finger, RING-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR003034:SAP domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17019 11-Aug-17 DroID_v2017_08 "Drer\zgc:171740, Drer\rffl, Drer\LOC103911786, Drer\rnf34a, Drer\rnf34b" - - "Xtro\rffl, Xtro\rnf34" "Mmus\Rffl, Mmus\Rnf34" "Hsap\RNF34, Hsap\RFFL" viable FBgn0034518 CG13430 - http://flybase.org/reports/FBgn0034518 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP70, CG33008, CG13430" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG13430 11-Aug-17 DroID_v2017_08 "Drer\tmprss15, Drer\zmp:0000001114, Drer\tmprss4a, Drer\si:ch211-165b19.9, Drer\zgc:55888" - Cele\try-1 - "Mmus\Tmprss11a, Mmus\Tmprss4, Mmus\Prss33, Mmus\Prss30, Mmus\Tmprss11g, Mmus\Prss55, Mmus\St14, Mmus\Prss50, Mmus\Tmprss2, Mmus\Tmprss11f, Mmus\Klk1b4" "Hsap\ST14, Hsap\TMPRSS4, Hsap\TMPRSS11F, Hsap\PRSS33, Hsap\TMPRSS11A, Hsap\PRSS50" FBgn0041224 Gr97a Gustatory receptor 97a http://flybase.org/reports/FBgn0041224 protein_coding_gene - sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "CG33083, Gr97D1, 97D.1, GR97D.1, CG31074, CG31073, Gr97a, GR97a, 97a" IPR013604:7TM chemoreceptor CG33083 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0033202 CG1339 - http://flybase.org/reports/FBgn0033202 protein_coding_gene taste receptor activity ; GO:0008527 | NOT inferred from sequence or structural similarity G-protein coupled receptor activity ; GO:0004930 | non-traceable author statement biological_process ; GO:0008150 | no biological data available - "CG1339, Gr43b, mdcds_19638" - CG1339 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC06383 E -0.844849574 -0.984651896 -1.849813775 0.859572038 -0.002863843 0.334049229 FBgn0016826 l(1)MZ13 lethal (1) MZ13 http://flybase.org/reports/FBgn0016826 - gene - - - "l(1)MZ13, M13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040395 Unc-76 Unc-76 http://flybase.org/reports/FBgn0040395 protein_coding_gene kinesin binding ; GO:0019894 | inferred from direct assay axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from biological aspect of ancestor with PANTHER:PTN001750789 phagocytosis ; GO:0006909 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001750789 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN001750789 "CG3981, EG:67A9.1, Dunc-76, l(1)G0158, l(1)G0066, l(1)G0310, l(1)G0360, l(1)G0333, unc-76, CG18851, BcDNA:GH10260, Unc-76, UNC-76, unc76" "IPR011680:Fasciculation and elongation protein zeta, FEZ" CG3981 11-Aug-17 DroID_v2017_08 "Drer\fez1, Drer\si:ch211-57i17.1, Drer\si:dkey-288i20.2" - Cele\unc-76 "Xtro\fez2, Xtro\fez1" "Mmus\Fez2, Mmus\Fez1" "Hsap\FEZ1, Hsap\FEZ2" "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,viable,fertile,paralytic,uncoordinated,neuroanatomy defective,visible" "third instar larva,axon,pupa,ganglion mother cell,chaeta,supernumerary" FBgn0027124 l(3)PG1-3 lethal (3) PG1-3 http://flybase.org/reports/FBgn0027124 - gene - - - l(3)PG1-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001135 gre green body http://flybase.org/reports/FBgn0001135 - gene - - - gre - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,body color defective" FBgn0263908 l(3)A41 - http://flybase.org/reports/FBgn0263908 gene - - - l(3)A41 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0263871 CR43718 - http://flybase.org/reports/FBgn0263871 non_protein_coding_gene - - - CR43718 - CR43718 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053867 His-Psi:CR33867 His-Psi:CR33867 http://flybase.org/reports/FBgn0053867 pseudogene_attribute - - - "CR33867, His-Psi:CR33867" - CR33867 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028618 l(2)35Cg lethal (2) 35Cg http://flybase.org/reports/FBgn0028618 gene - - - l(2)35Cg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003009 ord orientation disruptor http://flybase.org/reports/FBgn0003009 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VB08 female meiosis sister chromatid cohesion ; GO:0007066 | inferred from direct assay meiotic sister chromatid cohesion ; GO:0051177 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype male meiosis sister chromatid cohesion ; GO:0007065 | inferred from direct assay sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype maintenance of protein location in nucleus ; GO:0051457 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype gamete generation ; GO:0007276 | inferred from mutant phenotype "nuclear envelope ; GO:0005635 | inferred from direct assay male germ cell nucleus ; GO:0001673 | inferred from direct assay condensed chromosome, centromeric region ; GO:0000779 | inferred from direct assay female germ cell nucleus ; GO:0001674 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from direct assay" "ORD, CG3134, ord, Ord" - CG3134 11-Aug-17 DroID_v2017_08 - - - - - - adult stage spermatocyte

"meiotic cell cycle defective,viable,female fertile,reduced,male,male sterile,partially,recessive,female semi-sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,female sterile,male fertile" "nuclear chromosome3-70),cell cycle3-70),oocyte,meiosis & nuclear chromosome | male,meiotic cell cycle,nuclear chromosome | female,spermatocyte,cyst cell,male,testis,meiosis & nuclear chromosome3-70)" FBgn0023516 Pex5 Peroxin 5 http://flybase.org/reports/FBgn0023516 - protein_coding_gene peroxisome matrix targeting signal-1 binding ; GO:0005052 | inferred from biological aspect of ancestor with PANTHER:PTN000014838 "peroxisome organization ; GO:0007031 | inferred from mutant phenotype response to anesthetic ; GO:0072347 | inferred from mutant phenotype protein import into peroxisome matrix, docking ; GO:0016560 | inferred from biological aspect of ancestor with PANTHER:PTN000014838" peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:9719 peroxisomal membrane ; GO:0005778 | inferred from biological aspect of ancestor with PANTHER:PTN000014838 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000014838 "CG14815, EG:63B12.5, Pex5, DmelPex5, PEX5" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR024111:Peroxisomal targeting signal 1 receptor family, IPR019734:Tetratricopeptide repeat" CG14815 11-Aug-17 DroID_v2017_08 "Drer\pex5, Drer\pex5lb, Drer\pex5la" "Scer\PEX5, Scer\YMR018W" Cele\prx-5 "Xtro\ttc37, Xtro\pex5" "Mmus\Pex5l, Mmus\Pex5" "Hsap\PEX5, Hsap\PEX5L" "chemical sensitive,recessive,viable" FBgn0085577 CG41251 - http://flybase.org/reports/FBgn0085577 protein_coding_gene - - - CG41251 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082361 HM122 HM122 http://flybase.org/reports/FBgn0082361 gene - - - HM122 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010745 l(3)01344 lethal (3) 01344 http://flybase.org/reports/FBgn0010745 - gene - - - "l(3)1344, l(3)01344" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0034029 eIF2Bgamma eukaryotic translation initiation factor 2B subunit gamma http://flybase.org/reports/FBgn0034029 protein_coding_gene nucleotidyltransferase activity ; GO:0016779 | inferred from electronic annotation with InterPro:IPR005835 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000005786 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD:S000005786 translational initiation ; GO:0006413 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from sequence or structural similarity eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity with SGD:S000005786 eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity "CG8190, eIF2Bgamma, eIF2B-gamma" "IPR025877:MobA-like NTP transferase, IPR029044:Nucleotide-diphospho-sugar transferases, IPR005835:Nucleotidyl transferase domain" CG8190 11-Aug-17 DroID_v2017_08 Drer\eif2b3 Scer\GCD1 "Cele\ppp-1, Cele\tra-2" Xtro\eif2b3 Mmus\Eif2b3 Hsap\EIF2B3 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0053213 CG33213 - http://flybase.org/reports/FBgn0053213 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 biological_process ; GO:0008150 | no biological data available - "CG12260, CG33213" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG33213 11-Aug-17 DroID_v2017_08 "Drer\im:7147486, Drer\znf142" Scer\RME1 "Cele\C46E10.9, Cele\M03D4.4" - "Mmus\Zfp142, Mmus\Zfp574" "Hsap\ZNF574, Hsap\ZNF142" DRSC14487 K 0.427836091 0.191772301 -0.016524796 -0.227774899 -0.410403374 -1.634802345 FBgn0065333 l(2)SH1869 lethal (2) SH1869 http://flybase.org/reports/FBgn0065333 gene - - - "l(2)SH1869, l(2)SH2 1869" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039117 tst twister http://flybase.org/reports/FBgn0039117 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR016438 helicase activity ; GO:0004386 | inferred from sequence or structural similarity with SGD:S000004390 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN002281432 "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay ; GO:0070478 | inferred from biological aspect of ancestor with PANTHER:PTN002281541 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" Ski complex ; GO:0055087 | inferred from biological aspect of ancestor with PANTHER:PTN002281541 nucleus ; GO:0005634 | inferred by curator from GO:0000381 "SKI2, cg10210, Ski2, CG10210, tst, Ski2/tst, dSki2" "IPR025696:rRNA-processing arch domain, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR012961:ATP-dependent RNA helicase Ski2, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR016438:ATP-dependent RNA helicase Ski2, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10210 11-Aug-17 DroID_v2017_08 "Drer\skiv2l2, Drer\skiv2l" "Scer\SGS1, Scer\SKI2, Scer\MTR4" "Cele\skih-2, Cele\mtr-4" Xtro\skiv2l "Mmus\Skiv2l, Mmus\Ddx60, Mmus\Skiv2l2" "Hsap\DDX60L, Hsap\SKIV2L2, Hsap\SKIV2L" viable DRSC14212 E -0.190674354 -0.480329478 -2.946387522 -0.333193317 -0.361715794 1.077340184 FBgn0084911 W143 W143 http://flybase.org/reports/FBgn0084911 gene - - - W143 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0264607 CaMKII Calcium/calmodulin-dependent protein kinase II http://flybase.org/reports/FBgn0264607 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 calmodulin binding ; GO:0005516 | inferred from electronic annotation with InterPro:IPR013543 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from sequence or structural similarity inferred from direct assay calmodulin binding ; GO:0005516 | traceable author statement" long-term memory ; GO:0007616 | inferred from mutant phenotype cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN002389359 regulation of ovulation ; GO:0060278 | inferred from genetic interaction with Oamb neuromuscular junction development ; GO:0007528 | non-traceable author statement regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 regulation of filopodium assembly ; GO:0051489 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein phosphorylation ; GO:0006468 | non-traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | traceable author statement courtship behavior ; GO:0007619 | traceable author statement chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype learning or memory ; GO:0007611 | non-traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 calcium- and calmodulin-dependent protein kinase complex ; GO:0005954 | inferred from sequence or structural similarity dendrite ; GO:0030425 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay postsynaptic membrane ; GO:0045211 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay "CaMKII, CAMKII, dCAMKII, dCaMKII, CamKII, CG18069, CaM kinase, CaMK-II, Calcium/calmodulin-dependent protein kinase, camKII, CaM KII, CaM II, CAMKIId, CDPK1, Ca2+/calmodulin-dependent protein kinase II, calcium/calmodulin-dependent protein kinase II, DCK, CaMK II, CaM, CamKIIalpha, Cam, CAMKIIalpha, Camkii, l(4)16, l(4)ar, l(4)102EFb, camkII" "IPR032710:NTF2-like domain, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR013543:Calcium/calmodulin-dependent protein kinase II, association-domain, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG18069 11-Aug-17 DroID_v2017_08 "Drer\camk4, Drer\camk2b, Drer\camk1gb, Drer\camk1da, Drer\caska, Drer\camk2a, Drer\camk2b1, Drer\camk2d2, Drer\pnck, Drer\camk2d1, Drer\camk2g1, Drer\camk1b, Drer\camk1a, Drer\camk2g2" "Scer\PRR1, Scer\TDA1, Scer\CMK1, Scer\RCK2, Scer\DUN1, Scer\MEK1, Scer\RCK1, Scer\CMK2" "Cele\cmk-1, Cele\sel-5, Cele\unc-43" "Xtro\camk2b, Xtro\camk2g, Xtro\camk2a, Xtro\camk2d, Xtro\cask" "Mmus\Cask, Mmus\Camk1g, Mmus\Camk4, Mmus\Camk2d, Mmus\Camk2g, Mmus\Camk1, Mmus\Pnck, Mmus\Camk2a, Mmus\Camk2b, Mmus\Camk1d" "Hsap\PNCK, Hsap\CAMK1G, Hsap\CAMK1, Hsap\CAMK2G, Hsap\CAMK4, Hsap\CAMK2A, Hsap\CAMK2B, Hsap\CAMK2D, Hsap\CAMK1D, Hsap\CASK" adult stage adult head

FBgn0051944 tRNA:Gln-CTG-2-3 transfer RNA:Glutamine-CTG 2-3 http://flybase.org/reports/FBgn0051944 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002638.trna10-GlnCTG, tRNA:Q:CTG:AE002638-e, CR31944, chr2L.trna3-GlnCTG, tRNA:Gln-CTG-2-3, tRNA:CR31944, tRNA-Gln-CTG-2-3, CAG" - CR31944 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263033 CG43328 - http://flybase.org/reports/FBgn0263033 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG30459, CG43328" IPR026769:MICOS complex subunit Mic13 CG43328 11-Aug-17 DroID_v2017_08 Drer\si:dkey-78l4.14 - Cele\W04C9.2 - Mmus\2410015M20Rik Hsap\C19orf70 FBgn0001282 je jelly http://flybase.org/reports/FBgn0001282 - gene - - - je - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0002581 M(1)4BC Minute (1) 4BC http://flybase.org/reports/FBgn0002581 - gene - - - "M(1)4B/C, M(1)4BC" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031731 CG14007 - http://flybase.org/reports/FBgn0031731 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14007 - CG14007 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0036556 CG5830 - http://flybase.org/reports/FBgn0036556 protein_coding_gene CTD phosphatase activity ; GO:0008420 | inferred from sequence or structural similarity with HGNC:17077 phosphoprotein phosphatase activity ; GO:0004721 | inferred from biological aspect of ancestor with PANTHER:PTN000258719 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:17077 plasma membrane ; GO:0005886 | inferred from direct assay "CG5830, 24664944" "IPR004274:FCP1 homology domain, IPR011948:Dullard phosphatase domain, eukaryotic, IPR023214:HAD-like domain" CG5830 11-Aug-17 DroID_v2017_08 "Drer\ctdnep1b, Drer\ctdsplb, Drer\ctdnep1a, Drer\ctdspl2a, Drer\ctdspl3, Drer\ctdsp1, Drer\ctdsp2, Drer\ublcp1, Drer\ctdspl2b, Drer\ctdspla" "Scer\PSR1, Scer\PSR2, Scer\NEM1" "Cele\scpl-3, Cele\scpl-1" "Xtro\ublcp1, Xtro\ctdnep1, Xtro\ctdspl2, Xtro\ctdsp1, Xtro\ctdsp2, Xtro\ctdspl" "Mmus\Ctdnep1, Mmus\Ctdsp2, Mmus\Ublcp1, Mmus\Ctdspl, Mmus\Ctdspl2, Mmus\Ctdsp1" "Hsap\UBLCP1, Hsap\CTDSP2, Hsap\CTDNEP1, Hsap\CTDSPL2, Hsap\CTDSPL, Hsap\CTDSP1" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014206 l(1)17Aa lethal (1) 17Aa http://flybase.org/reports/FBgn0014206 - gene - - - "9130, l(1)17Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0084014 CG41451 - http://flybase.org/reports/FBgn0084014 protein_coding_gene - - - CG41451 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034959 CG11388 - http://flybase.org/reports/FBgn0034959 protein_coding_gene - - - "anon-EST:Posey287, CG11388, dibeta3GnT6" IPR029044:Nucleotide-diphospho-sugar transferases CG11388 11-Aug-17 DroID_v2017_08 "Drer\gxylt1a, Drer\gxylt1b, Drer\xxylt1, Drer\large, Drer\gxylt2, Drer\b4gat1" - Cele\lge-1 "Xtro\gxylt2, Xtro\gxylt1, Xtro\gyltl1b, Xtro\large, Xtro\xxylt1, Xtro\b4gat1" "Mmus\Large2, Mmus\Large1, Mmus\B4gat1, Mmus\Xxylt1, Mmus\Gxylt2, Mmus\Gxylt1" "Hsap\XXYLT1, Hsap\B4GAT1, Hsap\LARGE2, Hsap\LARGE1, Hsap\GXYLT1, Hsap\GXYLT2" "viable,fertile" FBgn0028744 CG5033 - http://flybase.org/reports/FBgn0028744 protein_coding_gene ribonucleoprotein complex binding ; GO:0043021 | inferred from biological aspect of ancestor with PANTHER:PTN000426773 "regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000463 | inferred from biological aspect of ancestor with PANTHER:PTN000426773 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000426773 PeBoW complex ; GO:0070545 | inferred from biological aspect of ancestor with PANTHER:PTN000426773" "EG:52C10.1, CG5033, dWDR36" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR012953:BOP1, N-terminal domain, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site, IPR028598:WD repeat BOP1/Erb1" CG5033 11-Aug-17 DroID_v2017_08 Drer\bop1 Scer\ERB1 Cele\Y48B6A.1 Xtro\bop1 Mmus\Bop1 "Hsap\PAFAH1B1, Hsap\BOP1" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0023165 Su(mg)1-2 Suppressor of modifier of gypsy 1-2 http://flybase.org/reports/FBgn0023165 - gene - - - Su(mg)1-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060923 l(3)S042238b lethal (3) S042238b http://flybase.org/reports/FBgn0060923 gene - - - "0422/38, l(3)S042238b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0002693 mch minute chaetae http://flybase.org/reports/FBgn0002693 - gene - - - mch - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male,male fertile" "macrochaeta,microchaeta" FBgn0050414 CG30414 - http://flybase.org/reports/FBgn0050414 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG3487, SP62, CG30414, FBgn0050414" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG30414 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\plat, Drer\tmprss4a, Drer\habp2" - Cele\try-3 - "Mmus\Klk1b5, Mmus\Gzmk, Mmus\Klk1b9, Mmus\Habp2, Mmus\Plat, Mmus\Tmprss4" "Hsap\TMPRSS4, Hsap\GZMK, Hsap\PLAT, Hsap\HABP2" "viable,fertile" FBgn0014265 l(2)k06524 lethal (2) k06524 http://flybase.org/reports/FBgn0014265 - gene molecular_function ; GO:0003674 | no biological data available lymph gland development ; GO:0048542 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)65/24, l(2)k06524, oho48A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval brain,embryonic/larval lymph gland" FBgn0000950 Fs(2)Bar Female sterile (2) Barsa http://flybase.org/reports/FBgn0000950 - gene - - - "Barsa, Fs(2)Sz1, Fs(2)Bar" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,dominant,female sterile germline-dependent" "dorsal appendage,egg,cephalopharyngeal skeleton" FBgn0030542 CG12481 - http://flybase.org/reports/FBgn0030542 protein_coding_gene - - - CG12481 - CG12481 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053449 5SrRNA:CR33449 5SrRNA:CR33449 http://flybase.org/reports/FBgn0053449 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33449, 5SrRNA:CR33449" - CR33449 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262078 JC01 - http://flybase.org/reports/FBgn0262078 gene - response to anesthetic ; GO:0072347 | inferred from mutant phenotype - JC01 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0039323 CG10559 - http://flybase.org/reports/FBgn0039323 protein_coding_gene - - - CG10559 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG10559 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.10, Cele\H06H21.8, Cele\C29F7.2, Cele\nhr-246, Cele\F59B1.8, Cele\C29F7.1" - - - viable FBgn0262341 mir-976 mir-976 stem loop http://flybase.org/reports/FBgn0262341 miRNA_gene - - - "dme-mir-976, miR-976, 976, mir-976, CR43048, miR976" - CR43048 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,lethal" "wing,wing vein L5" FBgn0039440 TwdlJ TweedleJ http://flybase.org/reports/FBgn0039440 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD extracellular region ; GO:0005576 | inferred from direct assay "CG5471, TwdlJ" IPR004145:Domain of unknown function DUF243 CG5471 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004437 pmst pmst http://flybase.org/reports/FBgn0004437 - gene - - - "PMST, pmst" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082627 S(CycE[JP])3.1 S(CycE[JP])3.1 http://flybase.org/reports/FBgn0082627 gene - - - S(CycE[JP])3.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0263597 Acp98AB Accessory gland protein 98AB http://flybase.org/reports/FBgn0263597 protein_coding_gene hormone activity ; GO:0005179 | non-traceable author statement "negative regulation of female receptivity, post-mating ; GO:0045434 | non-traceable author statement multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | traceable author statement "Acp98AB, Acp98B, CG31056, Acp98, Acp98Ab, CG43619" - CG43619 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male " male accessory gland

, male accessory gland main cell

" DRSC21837 E 0.625820062 -0.260901548 1.873042063 1.67255163 -0.175123677 0.718638171 FBgn0001769 l(1)M39 lethal (1) M39 http://flybase.org/reports/FBgn0001769 - gene - - - l(1)M39 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0016627 E(gl)2C Enhancer of glass 2C http://flybase.org/reports/FBgn0016627 - gene - - - E(gl)2C - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" rhabdomere FBgn0037124 CG14568 - http://flybase.org/reports/FBgn0037124 protein_coding_gene - - - "BcDNA:RE21944, CG14568" IPR032011:Domain of unknown function DUF4794 CG14568 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085296 CG34267 - http://flybase.org/reports/FBgn0085296 protein_coding_gene - - - CG34267 - CG34267 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265481 BG01744 - http://flybase.org/reports/FBgn0265481 gene - - - BG01744 - - 11-Aug-17 DroID_v2017_08 - - - - - - sleep defective FBgn0010761 l(3)01728 lethal (3) 01728 http://flybase.org/reports/FBgn0010761 - gene - - - l(3)01728 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "esophageal ganglion 1,esophageal ganglion 2,stomodeal nerve" FBgn0259993 CR42491 - http://flybase.org/reports/FBgn0259993 non_protein_coding_gene - - - CR42491 - CR42491 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004971 l(1)4Fa lethal (1) 4Fa http://flybase.org/reports/FBgn0004971 - gene - - - l(1)4Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000362 cpl cupola http://flybase.org/reports/FBgn0000362 - gene - - - cpl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male sterile,recessive" "adult head,eye,wing,tergite,abdominal tergite 6,abdominal tergite 7" FBgn0267959 CR46239 - http://flybase.org/reports/FBgn0267959 non_protein_coding_gene - - - "CR46239, lincRNA.772" - CR46239 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005079 fs(2)OW803 female sterile (2) OW803 http://flybase.org/reports/FBgn0005079 - gene - - - fs(2)OW803 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005740 l(1)TK232 lethal (1) TK232 http://flybase.org/reports/FBgn0005740 - gene - - - "l232, l(1)TK232" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000678 flrdA flight reduced A http://flybase.org/reports/FBgn0000678 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdA - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0063667 CG32335 - http://flybase.org/reports/FBgn0063667 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from sequence or structural similarity with HGNC:30204 hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from sequence or structural similarity with HGNC:30204" biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR015021 cellular_component ; GO:0005575 | no biological data available "BcDNA:RE72485, CG32335" IPR015021:Domain of unknown function DUF1907 CG32335 11-Aug-17 DroID_v2017_08 Drer\zgc:85789 - Cele\C24B5.4 Xtro\c11orf54 Mmus\4931406C07Rik Hsap\C11orf54 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0024514 l(3)06886 lethal (3) 06886 http://flybase.org/reports/FBgn0024514 - gene - - - l(3)06886 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038006 Cyp313a2 Cyp313a2 http://flybase.org/reports/FBgn0038006 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "313a2, CG10094, Cyp313a2, CYP313A2, Cyp313A2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10094 11-Aug-17 DroID_v2017_08 "Drer\cyp46a1.4, Drer\cyp20a1, Drer\cyp4t8, Drer\cyp46a1.3, Drer\cyp4f3, Drer\cyp46a1.1, Drer\cyp26b1, Drer\cyp4v7, Drer\cyp46a1.2, Drer\zgc:123299, Drer\cyp26a1, Drer\cyp4v8, Drer\cyp19a1b, Drer\cyp19a1a, Drer\LOC100329425, Drer\cyp26c1" "Scer\DIT2, Scer\ERG11, Scer\ERG5" "Cele\cyp-29A4, Cele\cyp-29A3" "Xtro\cyp19a1, Xtro\cyp4f22, Xtro\cyp4f2, Xtro\cyp26a1, Xtro\cyp26b1, Xtro\mgc108213, Xtro\cyp4b1.2, Xtro\cyp20a1, Xtro\LOC100488227, Xtro\cyp4b1, Xtro\cyp26c1, Xtro\LOC100487918, Xtro\cyp4v2" "Mmus\Cyp4f37, Mmus\Cyp4f40, Mmus\Cyp4f14, Mmus\Cyp46a1, Mmus\Cyp4a32, Mmus\Cyp4a12b, Mmus\Cyp4f15, Mmus\Cyp26b1, Mmus\Cyp4f39, Mmus\Cyp4f17, Mmus\Cyp4f13, Mmus\Cyp4v3, Mmus\Cyp4f18, Mmus\Cyp26a1, Mmus\Cyp4a14, Mmus\Cyp4f16, Mmus\Cyp4a12a, Mmus\Cyp20a1, Mmus\Cyp4x1, Mmus\Cyp4a31, Mmus\Cyp26c1, Mmus\Cyp4b1, Mmus\Cyp19a1, Mmus\Cyp4a10" "Hsap\CYP26B1, Hsap\CYP4F11, Hsap\CYP19A1, Hsap\CYP26C1, Hsap\CYP20A1, Hsap\CYP4X1, Hsap\CYP46A1, Hsap\CYP26A1, Hsap\CYP4V2, Hsap\CYP4A22, Hsap\CYP4Z1, Hsap\CYP4B1, Hsap\CYP4F3, Hsap\CYP4F22, Hsap\CYP4F12, Hsap\CYP4F2, Hsap\CYP4A11" "viable,fertile" FBgn0283461 Drs Drosomycin http://flybase.org/reports/FBgn0283461 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from direct assay antifungal humoral response ; GO:0019732 | traceable author statement defense response to fungus ; GO:0050832 | non-traceable author statement defense response to fungus ; GO:0050832 | traceable author statement innate immune response ; GO:0045087 | non-traceable author statement defense response to protozoan ; GO:0042832 | inferred from direct assay antifungal humoral response ; GO:0019732 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement cytolysis in other organism ; GO:0051715 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with UniProtKB:P30230 inferred from direct assay response to bacterium ; GO:0009617 | inferred from direct assay antibacterial humoral response ; GO:0019731 | traceable author statement defense response ; GO:0006952 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay "Drs, dros, CG10810, DIM 19, DIM 21, drs, drom, Drom, DRS, DRO, DROM, drsm, Crp, BcDNA:LP03851, Dros, drm, Drm, Droso, dmy1, DROS, IM21, Drosomycin" "IPR003614:Knottin, scorpion toxin-like" CG10810 11-Aug-17 DroID_v2017_08 - - - - - - "viable,immune response defective" FBgn0267554 CR45894 - http://flybase.org/reports/FBgn0267554 non_protein_coding_gene - - - CR45894 - CR45894 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0284255 Arpc4 "Actin-related protein 2/3 complex, subunit 4" http://flybase.org/reports/FBgn0284255 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with HGNC:707 actin binding ; GO:0003779 | inferred from sequence or structural similarity regulation of cell shape ; GO:0008360 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from sequence or structural similarity with HGNC:707 cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with HGNC:707 "Arc-p20, Arp-p20, CG5972, P-20 ARC, anon-EST:Posey49, BcDNA:RE43724, p20Arc, arc-p20, Arpc4, p20, ARPC4, l(2)SH1036, l(2)SH2 1036" "IPR034666:Arp2/3 complex subunit 2/4, IPR008384:Actin-related protein 2/3 complex subunit 4" CG5972 11-Aug-17 DroID_v2017_08 "Drer\arpc4l, Drer\arpc4" Scer\ARC19 Cele\arx-6 Xtro\arpc4 Mmus\Arpc4 "Hsap\ARPC4, Hsap\ARPC4-TTLL3" "lethal,recessive,cell shape defective,visible" wing DRSC02917 I 0.50256771 -1.796476883 -0.740272763 -0.927775043 -0.270433441 -0.741720588 FBgn0016696 Pitslre Pitslre http://flybase.org/reports/FBgn0016696 FBgn0013968 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity with SGD:S000001622 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091" regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000623380 protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity positive regulation of MyD88-dependent toll-like receptor signaling pathway ; GO:0034126 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from biological aspect of ancestor with PANTHER:PTN000623380 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 "PITSLRE, CG4268, group 3, Gta, Gat, Pitslre, cdk11, pitslre, PitsIre" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG4268 11-Aug-17 DroID_v2017_08 "Drer\cdk10, Drer\cdk11b, Drer\prpf4ba, Drer\cog5" "Scer\CDC28, Scer\SWE1" "Cele\K09F6.4, Cele\cdk-11.2, Cele\cdk-11.1" "Xtro\cdk11b, Xtro\cdk10" "Mmus\Cdk11b, Mmus\Cog5, Mmus\Cdk10" "Hsap\ZNF311, Hsap\CDK11B, Hsap\CDK10, Hsap\ZNF84, Hsap\CDK11A, Hsap\ZNF26, Hsap\ZNF709" " embryonic stage | late , embryonic stage | early , embryonic stage&&pupal stage&&adult stage " " embryonic nervous system

,

ubiquitous , embryonic central nervous system

" DRSC11874 EK 0.040949138 1.277209906 1.576646369 -1.301116576 -1.638855036 -0.975743589 FBgn0062579 Mod(var)600 Mod(var)600 http://flybase.org/reports/FBgn0062579 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "600, Mod(var)600" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0086405 BG01707 - http://flybase.org/reports/FBgn0086405 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01707 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0264885 CR44076 - http://flybase.org/reports/FBgn0264885 non_protein_coding_gene - - - CR44076 - CR44076 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014883 Ssb-cF4 Single stranded-binding protein cF4 http://flybase.org/reports/FBgn0014883 - gene - - - "cF4, Ssb-cF4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011128 l(1)Q202 lethal (1) Q202 http://flybase.org/reports/FBgn0011128 FBgn0010210 gene - - - l(1)Q202 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031250 Ent1 Equilibrative nucleoside transporter 1 http://flybase.org/reports/FBgn0031250 protein_coding_gene nucleoside transmembrane transporter activity ; GO:0005337 | inferred from sequence or structural similarity with HGNC:11003 inferred from sequence or structural similarity with HGNC:11004 nucleoside transport ; GO:0015858 | inferred from sequence or structural similarity with HGNC:11003 inferred from sequence or structural similarity with HGNC:11004 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002259 integral component of membrane ; GO:0016021 | inferred from sequence model "CG11907, DmENT1, anon-EST:fe2G2, Ent1, dENT1, ent1, DmEnt1" "IPR020846:Major facilitator superfamily domain, IPR002259:Equilibrative nucleoside transporter" CG11907 11-Aug-17 DroID_v2017_08 "Drer\LOC100334018, Drer\slc29a3, Drer\slc29a4, Drer\slc29a2, Drer\si:ch211-160d14.6, Drer\slc29a1b, Drer\slc29a1a" Scer\FUN26 "Cele\ent-4, Cele\ent-3, Cele\ent-2, Cele\ent-6, Cele\ent-1, Cele\ent-7" "Xtro\slc29a1, Xtro\slc29a2" "Mmus\Slc29a1, Mmus\Slc29a3, Mmus\Slc29a4, Mmus\Slc29a2" "Hsap\SLC29A2, Hsap\SLC29A4, Hsap\SLC29A1, Hsap\SLC29A3" "lethal,visible,viable" "scutellar bristle,ectopic,wing,trichogen cell" FBgn0032156 CG13124 - http://flybase.org/reports/FBgn0032156 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR003890 - - CG13124 "IPR003890:MIF4G-like, type 3, IPR016024:Armadillo-type fold" CG13124 11-Aug-17 DroID_v2017_08 "Drer\ctif, Drer\mif4gda, Drer\mif4gdb" - Cele\F44A2.5 "Xtro\mif4gd, Xtro\ctif" "Mmus\Mif4gd, Mmus\Ctif" "Hsap\MIF4GD, Hsap\CTIF" "viable,fertile" FBgn0053928 CG33928 - http://flybase.org/reports/FBgn0053928 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33928 IPR010512:Protein of unknown function DUF1091 CG33928 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028161 l(3)S036912 lethal (3) S036912 http://flybase.org/reports/FBgn0028161 gene - - - "0369/12, l(3)S036912" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052065 CG32065 - http://flybase.org/reports/FBgn0052065 protein_coding_gene - - - CG32065 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060936 l(3)S041315b lethal (3) S041315b http://flybase.org/reports/FBgn0060936 gene - - - "0413/15, l(3)S041315b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000776 fs(1)A1268 female sterile (1) A1268 http://flybase.org/reports/FBgn0000776 - gene - - - fs(1)A1268 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" egg FBgn0034920 CG5597 - http://flybase.org/reports/FBgn0034920 protein_coding_gene - - - "CT17698, CG5597, 5597" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG5597 11-Aug-17 DroID_v2017_08 Drer\zgc:123297 - - "Xtro\LOC100216153, Xtro\btn2a2" - Hsap\CADM2 viable DRSC04517 E 0.095482144 0.065224363 4.060675488 0.301437931 1.093982641 -0.4250697 FBgn0262867 Ptr Patched-related http://flybase.org/reports/FBgn0262867 protein_coding_gene receptor activity ; GO:0004872 | non-traceable author statement - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR003392 plasma membrane ; GO:0005886 | inferred from direct assay cytoplasmic vesicle membrane ; GO:0030659 | inferred from direct assay "Ptr, Dmptr, Ptr_Dm, CG11212, ptr, ptc-related-gene" "IPR000731:Sterol-sensing domain, IPR003392:Protein patched/dispatched" CG11212 11-Aug-17 DroID_v2017_08 "Drer\LOC100331480, Drer\ptchd4, Drer\si:ch211-250m6.7, Drer\ptchd1, Drer\ptchd3a" Scer\NCR1 "Cele\ptr-12, Cele\ptr-8, Cele\ptr-20, Cele\ptr-23, Cele\ptr-10, Cele\ptr-2, Cele\F43D9.1, Cele\ptr-21, Cele\ptr-24, Cele\ptr-11, Cele\ptr-4, Cele\ptr-17, Cele\ptr-19, Cele\ptr-5, Cele\ptr-18, Cele\ptr-15, Cele\ptr-1, Cele\ptr-16, Cele\ptr-14, Cele\ptr-22, Cele\ptr-9, Cele\ptr-6, Cele\ptr-13, Cele\ptr-3, Cele\daf-6" "Xtro\ptchd3, Xtro\ptchd4" "Mmus\Ptchd1, Mmus\Ptchd4, Mmus\Ptchd3" "Hsap\PTCHD3, Hsap\PTCHD1, Hsap\PTCHD4" FBgn0017377 l(1)HM442 lethal (1) HM442 http://flybase.org/reports/FBgn0017377 - gene - - - "HM-442, l(1)HM442" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265193 Atf-2 Activating transcription factor-2 http://flybase.org/reports/FBgn0265193 protein_coding_gene "protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay" stress-activated MAPK cascade ; GO:0051403 | inferred from direct assay cellular response to osmotic stress ; GO:0071470 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay positive regulation of heterochromatin assembly ; GO:0031453 | inferred from mutant phenotype heterochromatin maintenance ; GO:0070829 | inferred from mutant phenotype mucosal immune response ; GO:0002385 | inferred from mutant phenotype cellular response to heat ; GO:0034605 | inferred from direct assay regulation of triglyceride biosynthetic process ; GO:0010866 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype response to salt stress ; GO:0009651 | inferred from mutant phenotype polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear pericentric heterochromatin ; GO:0031618 | inferred from direct assay "Atf2, atf-2, CG44246, CG30420, CG12850, Atf-2, dATF-2, ATF2, dATF2, ATF-2, DM5" IPR004827:Basic-leucine zipper domain CG44246 11-Aug-17 DroID_v2017_08 "Drer\atf7b, Drer\crema, Drer\batf, Drer\fosl1a, Drer\atf2, Drer\creb1a, Drer\fosl2, Drer\si:ch211-153j24.3, Drer\atf1, Drer\batf3, Drer\jdp2b, Drer\npdc1b, Drer\creb5b, Drer\atf7a, Drer\fosaa, Drer\jdp2a, Drer\fosb, Drer\fosab, Drer\npdc1a" "Scer\ACA1, Scer\CIN5, Scer\SKO1, Scer\CST6" "Cele\crh-1, Cele\cab-1, Cele\atf-7, Cele\fos-1" "Xtro\fosb, Xtro\atf1, Xtro\atf3, Xtro\fosl2, Xtro\fosl1, Xtro\fos, Xtro\atf2, Xtro\creb5, Xtro\batf, Xtro\atf7" "Mmus\Fosl2, Mmus\Atf3, Mmus\Creb5, Mmus\Fosb, Mmus\Fos, Mmus\Fosl1, Mmus\Batf, Mmus\Atf1, Mmus\Atf7, Mmus\Batf2, Mmus\Jdp2, Mmus\Batf3, Mmus\Npdc1, Mmus\Atf2, Mmus\Creb1" "Hsap\FOSB, Hsap\BATF3, Hsap\CREB1, Hsap\ATF2, Hsap\CREB5, Hsap\BATF2, Hsap\CREM, Hsap\ATF3, Hsap\JDP2, Hsap\ATF1, Hsap\FOSL2, Hsap\FOS, Hsap\NPDC1, Hsap\BATF, Hsap\ATF7, Hsap\FOSL1" "suppressor of variegation,maternal effect,heat stress response defective,locomotor behavior defective,immune response defective,stress response defective,small body,visible,osmotic stress response defective" "LNv neuron,embryonic/larval fat body,wing vein" FBgn0002000 l(2)36Ad lethal (2) 36Ad http://flybase.org/reports/FBgn0002000 - gene - - - "l(2L)HT-11, l(2)HT-11, l(2)36Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0041107 ms(3)S125011b ms(3)S125011b http://flybase.org/reports/FBgn0041107 gene - - - "P2000, l(3)S125011, l(3)125011, 1250/11, ms(3)S125011, ms(3)S125011b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male sterile,heat sensitive" FBgn0267608 CR45946 - http://flybase.org/reports/FBgn0267608 pseudogene_attribute - - - CR45946 - CR45946 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021826 l(2)k16105 lethal (2) k16105 http://flybase.org/reports/FBgn0021826 - gene - - - l(2)k16105 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084110 nana nanahuatzin http://flybase.org/reports/FBgn0084110 gene - - - nana - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082957 snoRNA:Psi28S-3405d snoRNA:Psi28S-3405d http://flybase.org/reports/FBgn0082957 snoRNA_gene - - - "snoRNA:Psi28S-3405d, psi28s-3405d, CR34623" - CR34623 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267380 T:E2f1.1-230 E2f1 degron sequence http://flybase.org/reports/FBgn0267380 engineered_tag - - - T:E2f1.1-230 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035975 PGRP-LA Peptidoglycan recognition protein LA http://flybase.org/reports/FBgn0035975 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with HGNC:8904 inferred from sequence or structural similarity with protein_id:AAC31820.1 inferred from sequence or structural similarity with protein_id:BAA77210.1 peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues innate immune response ; GO:0045087 | non-traceable author statement peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement immune response ; GO:0006955 | inferred from sequence or structural similarity with HGNC:8904 inferred from sequence or structural similarity with protein_id:AAC31820.1 inferred from sequence or structural similarity with protein_id:BAA77210.1 response to bacterium ; GO:0009617 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | non-traceable author statement "CG4384, CG4361, CG18614, CG32042, PGRP-LA, PGRPLA, pgrp-la" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein" CG32042 11-Aug-17 DroID_v2017_08 "Drer\pglyrp2, Drer\pglyrp6, Drer\pglyrp5" - - "Xtro\pglyrp1, Xtro\pglyrp1, Xtro\pglyrp2" "Mmus\Pglyrp4, Mmus\Pglyrp1, Mmus\Pglyrp3, Mmus\Pglyrp2" "Hsap\PGLYRP2, Hsap\PGLYRP3, Hsap\PGLYRP4, Hsap\PGLYRP1" "viable,fertile,partially lethal,partially lethal - majority die,some die during pupal stage" FBgn0260429 CG42524 - http://flybase.org/reports/FBgn0260429 protein_coding_gene - - - CG42524 - CG42524 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005159 l(2)G145 lethal (2) G145 http://flybase.org/reports/FBgn0005159 - gene - - - l(2)G145 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263602 Tasp1 Taspase 1 http://flybase.org/reports/FBgn0263602 protein_coding_gene threonine-type endopeptidase activity ; GO:0004298 | inferred from direct assay endopeptidase activity ; GO:0004175 | inferred from direct assay threonine-type endopeptidase activity ; GO:0004298 | inferred from sequence alignment with HGNC:15859 proteolysis ; GO:0006508 | inferred from direct assay spermatogenesis ; GO:0007283 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype protein processing ; GO:0016485 | inferred from direct assay inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Tasp1, dTasp, Taspase1, l(3)72Dl, CG5241, anon-WO0118547.172, Taspase 1" "IPR000246:Peptidase T2, asparaginase 2, IPR029055:Nucleophile aminohydrolases, N-terminal" CG5241 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-103j14.5, Drer\tasp1, Drer\si:ch211-256m1.8, Drer\asrgl1" - Cele\K01G5.9 "Xtro\tasp1, Xtro\asrgl1" "Mmus\Asrgl1, Mmus\Tasp1" "Hsap\TASP1, Hsap\ASRGL1" FBgn0051694 CG31694 - http://flybase.org/reports/FBgn0051694 protein_coding_gene - positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG3098, CG15401, CG31694" "IPR006921:Interferon-related developmental regulator, C-terminal, IPR007701:Interferon-related developmental regulator, N-terminal, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG31694 11-Aug-17 DroID_v2017_08 "Drer\ifrd2, Drer\ifrd1" - Cele\F58B3.6 "Xtro\ifrd1, Xtro\ifrd2" "Mmus\Ifrd2, Mmus\Ifrd1" "Hsap\IFRD1, Hsap\IFRD2" "viable,fertile" FBgn0037832 Desi Desiccate http://flybase.org/reports/FBgn0037832 protein_coding_gene SH2 domain binding ; GO:0042169 | inferred from sequence model PDZ domain binding ; GO:0030165 | inferred from sequence model response to desiccation ; GO:0009269 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | inferred from mutant phenotype apical part of cell ; GO:0045177 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "Desi, CG14686" IPR006631:Protein of unknown function DM4/12 CG14686 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,viable,fertile" FBgn0031500 CG17221 - http://flybase.org/reports/FBgn0031500 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002085 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR013154 mushroom body development ; GO:0016319 | inferred from mutant phenotype" - "DM_7295851, CG17221" "IPR011032:GroES-like, IPR013154:Alcohol dehydrogenase, N-terminal, IPR016040:NAD(P)-binding domain, IPR020843:Polyketide synthase, enoylreductase domain" CG17221 11-Aug-17 DroID_v2017_08 "Drer\cryz, Drer\vat1, Drer\cryzl1, Drer\rtn4ip1, Drer\tp53i3" "Scer\AST2, Scer\ZTA1, Scer\YCR102C, Scer\YLR460C, Scer\YIM1, Scer\AST1, Scer\ADH3, Scer\YNL134C" "Cele\F39B2.3, Cele\rad-8" "Xtro\rtn4ip1, Xtro\tp53i3, Xtro\cryz, Xtro\vat1l, Xtro\cryzl1, Xtro\vat1" "Mmus\Cryz, Mmus\BC026585, Mmus\Zadh2, Mmus\Cryzl1, Mmus\Rtn4ip1, Mmus\Vat1l, Mmus\Vat1" "Hsap\ZADH2, Hsap\TP53I3, Hsap\VAT1L, Hsap\VAT1, Hsap\RTN4IP1, Hsap\CRYZL1, Hsap\CRYZ" "neuroanatomy defective,viable" adult mushroom body FBgn0005537 l(3)72De lethal (3) 72De http://flybase.org/reports/FBgn0005537 - gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - l(3)72De - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,recessive" organism FBgn0265746 CR44553 - http://flybase.org/reports/FBgn0265746 non_protein_coding_gene - - - CR44553 - CR44553 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263495 CR43484 - http://flybase.org/reports/FBgn0263495 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "CR43484, lincRNA.425" - CR43484 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002257 l(3)68Fb lethal (3) 68Fb http://flybase.org/reports/FBgn0002257 - gene - - - "rsg19, l(3)rsg19, l(3)68Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264416 FCO-A - http://flybase.org/reports/FBgn0264416 gene - - - FCO-A - - 11-Aug-17 DroID_v2017_08 - - - - - - egg chamber FBgn0024581 l(3)rN346 lethal (3) rN346 http://flybase.org/reports/FBgn0024581 - gene - - - l(3)rN346 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038769 CG10889 - http://flybase.org/reports/FBgn0038769 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 - - CG10889 "IPR000571:Zinc finger, CCCH-type, IPR011989:Armadillo-like helical, IPR021869:Ribonuclease Zc3h12a-like, NYN domain" CG10889 11-Aug-17 DroID_v2017_08 "Drer\khnyn, Drer\n4bp1, Drer\ccdc59, Drer\si:dkey-206d17.12, Drer\zc3h12b" - "Cele\Y24D9B.1, Cele\C30F12.1, Cele\Y59E9AR.8, Cele\Y51H4A.13, Cele\Y59E9AR.2, Cele\C29F5.3, Cele\rde-8" "Xtro\zc3h12b, Xtro\zc3h12a, Xtro\khnyn, Xtro\n4bp1" "Mmus\Zc3h12d, Mmus\Zc3h12a, Mmus\N4bp1, Mmus\Nynrin, Mmus\Zc3h12c, Mmus\Zc3h12b, Mmus\Khnyn, Mmus\Ccdc59" "Hsap\ZC3H12B, Hsap\ZC3H12A, Hsap\ZC3H12C, Hsap\N4BP1, Hsap\CCDC59, Hsap\ZC3H12D, Hsap\KHNYN, Hsap\NYNRIN" viable FBgn0019741 l(1)9 lethal (1) 9 http://flybase.org/reports/FBgn0019741 - gene - - - l(1)9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032971 ttm3 tiny tim 3 http://flybase.org/reports/FBgn0032971 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from biological aspect of ancestor with PANTHER:PTN000258719 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrial membrane organization ; GO:0007006 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrion organization ; GO:0007005 | inferred from sequence or structural similarity with ttm50 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000258720 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with ttm50 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q3ZCQ8 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000258720 "CG6691, ttm3" "IPR004274:FCP1 homology domain, IPR027111:Mitochondrial import inner membrane translocase subunit Tim50, IPR023214:HAD-like domain" CG6691 11-Aug-17 DroID_v2017_08 Drer\timm50 Scer\TIM50 Cele\scpl-4 Xtro\timm50 Mmus\Timm50 Hsap\TIMM50 viable FBgn0020573 anon-59Fa anon-59Fa http://flybase.org/reports/FBgn0020573 - gene - - - "12D3, anon-59Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002301 l(3)81Fb lethal (3) 81Fb http://flybase.org/reports/FBgn0002301 - gene - - - "l(3)Rh2, l(3)81Fb, 81Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264285 Su(Mir)2C2-1 - http://flybase.org/reports/FBgn0264285 gene - - - Su(Mir)2C2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034293 CG14495 - http://flybase.org/reports/FBgn0034293 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14495 IPR007931:Protein of unknown function DUF725 CG14495 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260609 2L2615 - http://flybase.org/reports/FBgn0260609 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2615 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0025933 hip11 hb-interacting protein 11 http://flybase.org/reports/FBgn0025933 - gene - - - hip11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011082 l(1)Q40 lethal (1) Q40 http://flybase.org/reports/FBgn0011082 FBgn0010210 gene - - - l(1)Q40 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036629 GluRS-m "Glutamyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0036629 protein_coding_gene "glutamate-tRNA ligase activity ; GO:0004818 | inferred from electronic annotation with InterPro:IPR004527 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR033910 tRNA binding ; GO:0000049 | inferred from electronic annotation with InterPro:IPR008925 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000924, InterPro:IPR001412, InterPro:IPR004527, InterPro:IPR020058, InterPro:IPR020061 glutamate-tRNA ligase activity ; GO:0004818 | traceable author statement" glutamyl-tRNA aminoacylation ; GO:0006424 | inferred from electronic annotation with InterPro:IPR004527 glutamyl-tRNA aminoacylation ; GO:0006424 | traceable author statement "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000924, InterPro:IPR004527, InterPro:IPR020061 mitochondrion ; GO:0005739 | traceable author statement" "CG4573, GluRS-m" "IPR000924:Glutamyl/glutaminyl-tRNA synthetase, IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR004527:Glutamate-tRNA ligase, bacterial/mitochondrial, IPR008925:Aminoacyl-tRNA synthetase, class I, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR033910:Glutamyl-tRNA synthetase, IPR020058:Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain, IPR020061:Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain, IPR020751:Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2" CG4573 11-Aug-17 DroID_v2017_08 Drer\zgc:153247 Scer\MSE1 Cele\ears-2 Xtro\ears2 Mmus\Ears2 Hsap\EARS2 "viable,visible" trichogen cell FBgn0053993 CG33993 - http://flybase.org/reports/FBgn0053993 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13289, CG13290, CG33993" IPR000980:SH2 domain CG33993 11-Aug-17 DroID_v2017_08 - Scer\TEP1 Cele\shc-2 - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0032586 Tpr2 Tetratricopeptide repeat protein 2 http://flybase.org/reports/FBgn0032586 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with ECOGENE:EG10240 protein folding ; GO:0006457 | inferred from sequence or structural similarity with ECOGENE:EG10240 cellular_component ; GO:0005575 | no biological data available "tpr2, dTPR2, dtpr2, EU3220, BEST:LD24941, CG4599, Tpr2, dtrpr2, Trp2, Tpr-2, dTpr2, TPR2" "IPR018253:DnaJ domain, conserved site, IPR001623:DnaJ domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR013105:Tetratricopeptide repeat 2" CG4599 11-Aug-17 DroID_v2017_08 "Drer\dnajc7, Drer\dnajc3a, Drer\dnajb11" "Scer\SIS1, Scer\JJJ2, Scer\HLJ1" "Cele\dnj-20, Cele\dnj-3, Cele\dnj-7" Xtro\dnajc7 "Mmus\Dnajc7, Mmus\Dnajc3, Mmus\Dnajb11" "Hsap\DNAJB11, Hsap\DNAJC3, Hsap\DNAJC7" "visible,viable" "wing,eye" FBgn0031490 CG17264 - http://flybase.org/reports/FBgn0031490 protein_coding_gene - - - CG17264 IPR000859:CUB domain CG17264 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005210 l(3)LVMR lethal (3) LVMR http://flybase.org/reports/FBgn0005210 - gene - - - l(3)LVMR - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029812 Prosbeta2R1 Proteasome beta2 subunit-related 1 http://flybase.org/reports/FBgn0029812 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | inferred from sequence or structural similarity with SGD:S000005683" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000005683 "proteasome core complex, beta-subunit complex ; GO:0019774 | inferred from sequence or structural similarity with SGD:S000005683" "CG18341, Prosbeta2R1, beta2R1" "IPR023333:Proteasome B-type subunit, IPR000243:Peptidase T1A, proteasome beta-subunit, IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR024689:Proteasome beta subunit, C-terminal, IPR029055:Nucleophile aminohydrolases, N-terminal" CG18341 11-Aug-17 DroID_v2017_08 "Drer\psmb10, Drer\psmb5, Drer\psmb7, Drer\zgc:92791, Drer\psmb8a" "Scer\PUP1, Scer\PRE2" "Cele\pbs-2, Cele\pbs-5" "Xtro\psmb7, Xtro\psmb7.2" "Mmus\Psmb5, Mmus\Psmb10, Mmus\Psmb7, Mmus\Psmb8" "Hsap\PSMB5, Hsap\PSMB7, Hsap\PSMB10, Hsap\PSMB8" FBgn0260379 GSd246 - http://flybase.org/reports/FBgn0260379 gene - - - GSd246 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0267948 CR46228 - http://flybase.org/reports/FBgn0267948 non_protein_coding_gene - - - "CR46228, lincRNA.729" - CR46228 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015219 Eig4F Ecdysone-induced gene 4F http://flybase.org/reports/FBgn0015219 - gene - - - "4F, Eig4F" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000885 fs(1)M83 female sterile (1) M83 http://flybase.org/reports/FBgn0000885 - gene - - - fs(1)M83 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0266945 CR45396 - http://flybase.org/reports/FBgn0266945 non_protein_coding_gene - - - CR45396 - CR45396 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262354 CG43052 - http://flybase.org/reports/FBgn0262354 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43052, MB6.chr2L.pasa.1468" - CG43052 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032036 CG13384 - http://flybase.org/reports/FBgn0032036 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 CG13384 "IPR013057:Amino acid transporter, transmembrane domain" CG13384 11-Aug-17 DroID_v2017_08 "Drer\slc36a1, Drer\slc36a4" "Scer\AVT4, Scer\AVT3" "Cele\slc-36.2, Cele\slc-36.4, Cele\slc-36.5, Cele\slc-36.3, Cele\Y43F4B.7, Cele\Y18D10A.23, Cele\skat-1" "Xtro\slc36a1, Xtro\slc36a4" "Mmus\Slc36a4, Mmus\Slc36a1, Mmus\Slc36a3, Mmus\Slc36a2" "Hsap\SLC36A2, Hsap\SLC36A3, Hsap\SLC36A1, Hsap\SLC36A4" viable FBgn0032211 CG13138 - http://flybase.org/reports/FBgn0032211 protein_coding_gene - - - CG13138 - CG13138 11-Aug-17 DroID_v2017_08 - - Cele\T26C11.2 - Mmus\Ggn "Hsap\TPRX1, Hsap\GGN" viable FBgn0019785 l(1)20 lethal (1) 20 http://flybase.org/reports/FBgn0019785 - gene - - - l(1)20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034884 Eglp3 Entomoglyceroporin 3 http://flybase.org/reports/FBgn0034884 protein_coding_gene water channel activity ; GO:0015250 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 channel activity ; GO:0015267 | inferred from sequence or structural similarity with Drip transmembrane transport ; GO:0055085 | inferred from sequence or structural similarity with Drip ion transmembrane transport ; GO:0034220 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Drip "CG17662, Aqp17662, Eglp3, Eglp 3" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR022357:Major intrinsic protein, conserved site, IPR023271:Aquaporin-like" CG17662 11-Aug-17 DroID_v2017_08 "Drer\mipa, Drer\aqp8b, Drer\aqp8a.2, Drer\aqp1a.1, Drer\aqp3a, Drer\aqp10a, Drer\aqp9b, Drer\aqp3b, Drer\aqp10b, Drer\si:dkey-30h22.11, Drer\aqp1a.2, Drer\aqp8a.1, Drer\mipb, Drer\aqp4, Drer\aqp7" "Scer\YFL054C, Scer\AQY1, Scer\AQY2, Scer\YLL053C, Scer\FPS1" "Cele\aqp-8, Cele\aqp-5, Cele\aqp-6, Cele\aqp-4, Cele\aqp-2, Cele\aqp-3, Cele\aqp-7" "Xtro\aqp5, Xtro\aqp9, Xtro\aqp3, Xtro\LOC100489792, Xtro\aqp8, Xtro\mip, Xtro\aqp7, Xtro\aqp10, Xtro\aqp2, Xtro\fam188b" "Mmus\Aqp2, Mmus\Aqp9, Mmus\Aqp3, Mmus\Aqp4, Mmus\Aqp1, Mmus\Aqp5, Mmus\Aqp6, Mmus\Fam188b, Mmus\Aqp8, Mmus\Aqp7, Mmus\Mip" "Hsap\AQP10, Hsap\AQP2, Hsap\FAM188B2, Hsap\AQP9, Hsap\AQP1, Hsap\AQP4, Hsap\AQP8, Hsap\AQP7, Hsap\AQP6, Hsap\LOC100509620, Hsap\AQP3, Hsap\MIP, Hsap\AQP5" viable FBgn0082186 l(3)SzB67Aa lethal (3) SzB67Aa http://flybase.org/reports/FBgn0082186 gene - - - l(3)SzB67Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261718 DJ996 - http://flybase.org/reports/FBgn0261718 gene - - - DJ996 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024926 Su(var)3-c1101 Su(var)3-c1101 http://flybase.org/reports/FBgn0024926 - gene - - - "Su-var(3)c1101, Su(var)3-c1101" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034541 CG13437 - http://flybase.org/reports/FBgn0034541 protein_coding_gene - - - CG13437 - CG13437 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011562 ams adult male-specific transcript http://flybase.org/reports/FBgn0011562 - gene - - - ams - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085742 CR40546 - http://flybase.org/reports/FBgn0085742 rRNA_gene - - - CR40546 - CR40546 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031174 CG1486 - http://flybase.org/reports/FBgn0031174 protein_coding_gene carboxy-lyase activity ; GO:0016831 | inferred from electronic annotation with InterPro:IPR002129 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 carboxylic acid metabolic process ; GO:0019752 | inferred from electronic annotation with InterPro:IPR002129 - CG1486 "IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG1486 11-Aug-17 DroID_v2017_08 Drer\pdxdc1 Scer\DPL1 Cele\C14H10.3 Xtro\pdxdc1 Mmus\Pdxdc1 "Hsap\LOC102724985, Hsap\PDXDC1" FBgn0065555 l(2)SH1016 lethal (2) SH1016 http://flybase.org/reports/FBgn0065555 gene - - - "l(2)SH1016, l(2)SH2 1016" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053527 SIFa SIFamide http://flybase.org/reports/FBgn0053527 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity receptor agonist activity ; GO:0048018 | inferred from physical interaction with SIFaR hormone activity ; GO:0005179 | non-traceable author statement neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with SIFaR "mating behavior, sex discrimination ; GO:0048047 | inferred from mutant phenotype positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay negative regulation of female receptivity ; GO:0007621 | inferred from mutant phenotype" "extracellular space ; GO:0005615 | inferred by curator from GO:0048018,GO:0071855" "Drm-IFa, CG33527, SIFa, Neb-LFamide, SIFamide, Drm-SIFa, IFa, SIFR, IFAMIDE" - CG33527 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,male,female" FBgn0025387 CG12184 - http://flybase.org/reports/FBgn0025387 - protein_coding_gene - - - "EG:66A1.3, CG12184, GH15731P" IPR029299:ALMS motif CG12184 11-Aug-17 DroID_v2017_08 - - - - Mmus\Map7d1 - "partially lethal - majority die,some die during pupal stage" FBgn0260998 AGAR-11 Autosomal general anesthetic resistant 11 http://flybase.org/reports/FBgn0260998 gene - - - AGAR-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0058327 CG40327 - http://flybase.org/reports/FBgn0058327 protein_coding_gene - - - CG40327 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028880 CG15256 - http://flybase.org/reports/FBgn0028880 protein_coding_gene - - - "BG:DS04862.2, CG15256" - CG15256 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0266392 CR45032 - http://flybase.org/reports/FBgn0266392 non_protein_coding_gene - - - CR45032 - CR45032 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000987 Fs(2)Kom Female sterile (2) Kompolt http://flybase.org/reports/FBgn0000987 - gene - - - "Kom, Fs(2)Sz8, Fs(2)Kom" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,dominant" embryo FBgn0266645 CR45152 - http://flybase.org/reports/FBgn0266645 non_protein_coding_gene - - - CR45152 - CR45152 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020342 anon-57Ca anon-57Ca http://flybase.org/reports/FBgn0020342 - gene - - - "525, anon-57Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029037 l(2)J27 lethal (2) J27 http://flybase.org/reports/FBgn0029037 gene - - - "J27, l(2)J27" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067736 l(1)G0357 lethal (1) G0357 http://flybase.org/reports/FBgn0067736 gene - - - l(1)G0357 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0010146 l(3)62g lethal (3) 62g http://flybase.org/reports/FBgn0010146 - gene - - - l(3)62g - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013462 fs(3)neo71 fs(3)neo71 http://flybase.org/reports/FBgn0013462 - gene - - - fs(3)neo71 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal,maternal effect" FBgn0022121 l(2)k06612 lethal (2) k06612 http://flybase.org/reports/FBgn0022121 - gene - - - l(2)k06612 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267947 CR46227 - http://flybase.org/reports/FBgn0267947 non_protein_coding_gene - - - "CR46227, lincRNA.654" - CR46227 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031471 CG3117 - http://flybase.org/reports/FBgn0031471 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "SPH94, c-SPH94, CG3117" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG3117 11-Aug-17 DroID_v2017_08 - - Cele\try-1 - "Mmus\Klkb1, Mmus\Klk1b27, Mmus\Klk1b5, Mmus\Klk1b22, Mmus\Klk1b26, Mmus\Klk11, Mmus\F11, Mmus\Klk1b21, Mmus\Klk1b3, Mmus\Klk1b24, Mmus\F9, Mmus\Klk1b16, Mmus\Klk1b1, Mmus\Klk1b8, Mmus\Klk1b9, Mmus\Klk1b11, Mmus\Klk1, Mmus\Klk1b4, Mmus\Egfbp2" "Hsap\KLK2, Hsap\KLKB1, Hsap\F9, Hsap\KLK11, Hsap\KLK3, Hsap\F11, Hsap\PLG, Hsap\KLK1" "viable,visible" trichogen cell FBgn0259265 EP-457 - http://flybase.org/reports/FBgn0259265 gene - - - EP-457 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0001751 l(1)HM24 lethal (1) HM24 http://flybase.org/reports/FBgn0001751 - gene - - - l(1)HM24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0037067 Cpr78Ca Cuticular protein 78Ca http://flybase.org/reports/FBgn0037067 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr78Ca, CG11310, DmelCpr78Ca" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG11310 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0065601 l(2)SH0866 lethal (2) SH0866 http://flybase.org/reports/FBgn0065601 gene - - - "l(2)SH0866, l(2)SH2 0866" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0042151 CG18828 - http://flybase.org/reports/FBgn0042151 protein_coding_gene - - - CG18828 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037439 CG10286 - http://flybase.org/reports/FBgn0037439 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN001410872 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN001410872 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN001410872 cellular_component ; GO:0005575 | no biological data available CG10286 "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG10286 11-Aug-17 DroID_v2017_08 Drer\heatr3 Scer\SYO1 - Xtro\heatr3 Mmus\Heatr3 Hsap\HEATR3 "viable,fertile" FBgn0011521 l(3)rM731 lethal (3) rM731 http://flybase.org/reports/FBgn0011521 - gene - - - l(3)rM731 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069934 CG41117 - http://flybase.org/reports/FBgn0069934 protein_coding_gene - - - CG41117 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002586 M(1)8F Minute (1) 8F http://flybase.org/reports/FBgn0002586 - gene - - - "M(1)8E/F, M(1)14-171, M(1)8F" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,visible" macrochaeta FBgn0264900 CR44091 - http://flybase.org/reports/FBgn0264900 non_protein_coding_gene - - - "CR44091, lincRNA.915" - CR44091 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262163 betaNACtes5 "Nascent-associated complex beta-subunit-like, testis 5" http://flybase.org/reports/FBgn0262163 pseudogene_attribute - - - "betaNACtes5, CR42877" - CR42877 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050064 CG30064 - http://flybase.org/reports/FBgn0050064 protein_coding_gene - - - CG30064 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031397 CG15385 - http://flybase.org/reports/FBgn0031397 protein_coding_gene acid phosphatase activity ; GO:0003993 | inferred from electronic annotation with InterPro:IPR000560 lysophosphatidic acid phosphatase activity ; GO:0052642 | inferred from sequence or structural similarity with HGNC:29609 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:29609 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:29609 CG15385 "IPR000560:Histidine phosphatase superfamily, clade-2, IPR029033:Histidine phosphatase superfamily, IPR033379:Histidine acid phosphatase active site" CG15385 11-Aug-17 DroID_v2017_08 "Drer\pxylp1, Drer\acp6, Drer\acp2" - "Cele\pho-5, Cele\pho-14, Cele\acp-7, Cele\pho-6, Cele\pho-9, Cele\ZK809.9, Cele\pho-4, Cele\pho-8, Cele\pho-1, Cele\ZK792.1, Cele\acp-6, Cele\C27A2.12, Cele\pho-13, Cele\pho-7, Cele\pho-12" Xtro\pxylp1 "Mmus\Acp2, Mmus\Acp6, Mmus\Acpt, Mmus\Pxylp1, Mmus\Acpp" "Hsap\ACP6, Hsap\ACP2, Hsap\ACPP, Hsap\PXYLP1, Hsap\ACPT" FBgn0044335 674 674 http://flybase.org/reports/FBgn0044335 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available 674 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031264 CG11835 - http://flybase.org/reports/FBgn0031264 protein_coding_gene - - - CG11835 IPR002715:Nascent polypeptide-associated complex NAC domain CG11835 11-Aug-17 DroID_v2017_08 "Drer\tab2, Drer\btf3l4, Drer\tab3, Drer\btf3, Drer\rab11fip5a" "Scer\BTT1, Scer\SRP40, Scer\DEF1, Scer\EGD1, Scer\NUP60, Scer\SIR4, Scer\WWM1, Scer\YML020W" "Cele\icd-1, Cele\dao-5" "Xtro\btf3, Xtro\rab11fip5, Xtro\rab11fip2, Xtro\btf3l4" "Mmus\Cx3cl1, Mmus\Rab11fip2, Mmus\Rab11fip1, Mmus\Btf3, Mmus\Tab3, Mmus\Tab2, Mmus\Nolc1, Mmus\Btf3l4, Mmus\Rab11fip5" "Hsap\NOLC1, Hsap\BTF3L4, Hsap\RAB11FIP1, Hsap\CX3CL1, Hsap\RAB11FIP5, Hsap\BTF3, Hsap\ABI3BP, Hsap\RAB11FIP2, Hsap\TAB3, Hsap\TAB2" DRSC00326 K 1.473266836 0.077467174 -0.407601442 -0.597030192 1.588041769 0.452451507 FBgn0262297 mir-2496 mir-2496 stem loop http://flybase.org/reports/FBgn0262297 miRNA_gene - - - "mir-2496, CR43004, dme-mir-2496, miR-2496" - CR43004 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266177 pre-mod(mdg4)-I - http://flybase.org/reports/FBgn0266177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-I, CG44883" "IPR007588:Zinc finger, FLYWCH-type" CG44883 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Flywch1, Mmus\Flywch2" - FBgn0264980 CR44131 - http://flybase.org/reports/FBgn0264980 non_protein_coding_gene - - - CR44131 - CR44131 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052406 PVRAP PVR adaptor protein http://flybase.org/reports/FBgn0052406 protein_coding_gene SH3/SH2 adaptor activity ; GO:0005070 | inferred from physical interaction with Pvr TORC1 signaling ; GO:0038202 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG6062, CG13292, CG32406, PVRAP" IPR000980:SH2 domain CG32406 11-Aug-17 DroID_v2017_08 - Scer\TEP1 Cele\shc-2 - - - "viable,fertile,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC10577 E 0.332946321 -0.130282994 1.665399125 0.195190791 -0.088462472 0.040212408 FBgn0261276 Opa1 Optic atrophy 1 http://flybase.org/reports/FBgn0261276 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001401, InterPro:IPR030381 GTPase activity ; GO:0003924 | inferred from sequence model microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000170013 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000170013" mitochondrial fission ; GO:0000266 | inferred from biological aspect of ancestor with PANTHER:PTN000902162 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype dynamin family protein polymerization involved in mitochondrial fission ; GO:0003374 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 mitochondrial fusion ; GO:0008053 | inferred from mutant phenotype negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway ; GO:1902236 | inferred from sequence or structural similarity with UniProtKB:O60313 compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype positive regulation of mitochondrial fusion ; GO:0010636 | inferred from mutant phenotype mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O60313 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:8140 "opa1, Opa1-like, CG8479, l(2)s3475, OPA1, OPA1-like, dOpa1, Opa1, dOPA1, opa1-like" "IPR030381:Dynamin-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001401:Dynamin, GTPase domain, IPR022812:Dynamin superfamily, IPR033047:Dynamin-like 120 kDa protein, mitochondrial" CG8479 11-Aug-17 DroID_v2017_08 "Drer\opa1, Drer\mxe" "Scer\MGM1, Scer\DNM1, Scer\VPS1" Cele\eat-3 Xtro\opa1 Mmus\Opa1 Hsap\OPA1 FBgn0263890 D75 - http://flybase.org/reports/FBgn0263890 gene - - - D75 - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0013581 l(3)82Fi lethal (3) 82Fi http://flybase.org/reports/FBgn0013581 - gene - - - l(3)82Fi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001953 l(2)28Ab lethal (2) 28Ab http://flybase.org/reports/FBgn0001953 - gene - - - "K, l(2)28Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085513 CG40748 - http://flybase.org/reports/FBgn0085513 protein_coding_gene - - - CG40748 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065369 l(2)SH1708 lethal (2) SH1708 http://flybase.org/reports/FBgn0065369 gene - - - "l(2)SH1708, l(2)SH2 1708" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030074 CG12662 - http://flybase.org/reports/FBgn0030074 protein_coding_gene - - - CG12662 IPR010512:Protein of unknown function DUF1091 CG12662 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051570 tRNA:Ala-AGC-2-2 transfer RNA:Alanine-AGC 2-2 http://flybase.org/reports/FBgn0051570 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna10-AlaAGC, tRNA:A:AGC:AE002708-a, tRNA:-?:90Ca, CR31570, tRNA[[Ala]], chr3R.trna16-AlaAGC, tRNA-Ala-AGC-2-2, tRNA:Ala-AGC-2-2, tRNA:CR31570, GCU" - CR31570 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038363 Acyp2 Acylphosphatase 2 http://flybase.org/reports/FBgn0038363 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from direct assay acylphosphatase activity ; GO:0003998 | inferred from direct assay cellular metabolic process ; GO:0044237 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement "AcPDro2, CG18505, Acyp2" "IPR001792:Acylphosphatase-like domain, IPR017968:Acylphosphatase, conserved site, IPR020456:Acylphosphatase" CG18505 11-Aug-17 DroID_v2017_08 "Drer\acyp1, Drer\acyp2" - - "Xtro\acyp1, Xtro\acyp2" "Mmus\Acyp2, Mmus\Acyp1" "Hsap\ACYP2, Hsap\ACYP1" viable FBgn0001484 l(1)10Ad lethal (1) 10Ad http://flybase.org/reports/FBgn0001484 - gene - - - "l(1)BP8, Q66, l(1)dp05, l(1)dp024, l(1)10Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,dominant,cold sensitive,female sterile,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,partially,rescuable maternal effect" "tergite,embryonic/first instar larval cuticle,germline clone,embryonic head" FBgn0054007 CG34007 - http://flybase.org/reports/FBgn0054007 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1020, CG34007" - CG34007 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022195 l(2)k04909b lethal (2) k04909b http://flybase.org/reports/FBgn0022195 - gene - - - l(2)k04909b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264411 FCE-D - http://flybase.org/reports/FBgn0264411 gene - - - FCE-D - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,somatic clone" FBgn0050009 CR30009 - http://flybase.org/reports/FBgn0050009 non_protein_coding_gene - - - "BcDNA:RE30084, CR30009, MRE31" - CR30009 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050456 CG30456 - http://flybase.org/reports/FBgn0050456 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with trio imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with trio cellular_component ; GO:0005575 | no biological data available "CG15612, CG15613, CG30456" "IPR000219:Dbl homology (DH) domain, IPR011993:PH domain-like" CG30456 11-Aug-17 DroID_v2017_08 "Drer\arhgef25a, Drer\mcf2a, Drer\si:dkey-65j6.2, Drer\trioa, Drer\arhgef40, Drer\zgc:158766, Drer\kalrna, Drer\arhgef25b, Drer\triob, Drer\quo, Drer\si:dkey-91i10.2, Drer\plekhg4, Drer\kalrnb, Drer\LOC101883939" "Scer\ROM2, Scer\CDC24, Scer\ROM1" "Cele\unc-73, Cele\Y95B8A.12, Cele\cgef-1, Cele\tiam-1" "Xtro\kalrn, Xtro\arhgef40" "Mmus\Arhgef40, Mmus\Trio, Mmus\Kalrn, Mmus\Arhgef25, Mmus\Plekhg4, Mmus\D630003M21Rik" "Hsap\TRIO, Hsap\ARHGEF25, Hsap\PLEKHG4B, Hsap\SLC26A10, Hsap\PLEKHG4, Hsap\ARHGEF40, Hsap\KALRN" viable FBgn0024872 l(2)k05627 lethal (2) k05627 http://flybase.org/reports/FBgn0024872 - gene - - - l(2)k05627 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264418 FCO-C - http://flybase.org/reports/FBgn0264418 gene - - - FCO-C - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0005550 l(3)85Ai lethal (3) 85Ai http://flybase.org/reports/FBgn0005550 - gene - - - "X, l(3)85Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022666 Dep3 Dep3 http://flybase.org/reports/FBgn0022666 - gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "DEP3, Dep3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013940 E(sina)46C Enhancer of seven in absentia at 46C http://flybase.org/reports/FBgn0013940 - gene - - - E(sina)46C - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" photoreceptor cell R7 FBgn0082978 snoRNA:Psi28S-3091b snoRNA:Psi28S-3091b http://flybase.org/reports/FBgn0082978 snoRNA_gene - - - "snoRNA:Psi28S-3091b, psi28s-3091b, CR34609" - CR34609 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264406 FCG-I - http://flybase.org/reports/FBgn0264406 gene - - - FCG-I - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0039861 pasha partner of drosha http://flybase.org/reports/FBgn0039861 protein_coding_gene double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V9K7 germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from mutant phenotype imaginal disc growth ; GO:0007446 | inferred from mutant phenotype primary miRNA processing ; GO:0031053 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "DGCR8, CG1800, dmDGCR8, Pasha, cg1800, pasha, PASHA" IPR014720:Double-stranded RNA-binding domain CG1800 11-Aug-17 DroID_v2017_08 Drer\dgcr8 - Cele\pash-1 Xtro\dgcr8 Mmus\Dgcr8 Hsap\DGCR8 "lethal - all die before end of P-stage,some die during pharate adult stage,neurophysiology defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die during pupal stage,decreased cell number,neuroanatomy defective,visible,lethal - all die before end of larval stage,recessive,some die during third instar larval stage,lethal,viable" "oocyte,germline clone,eye disc,central nervous system,alpha'/beta' Kenyon cell,alpha/beta Kenyon cell,mushroom body,gamma Kenyon cell,adult antennal lobe projection neuron DL1 adPN,somatic clone,eye,wing,chaeta & mesothoracic tergum | somatic clone,imaginal disc,embryonic/larval optic lobe,dendrite & ad PN | somatic clone,dendrite & lPN | somatic clone,dendrite & vPN | somatic clone,dendrite & DL1 adPN | somatic clone,dendrite & VA1d adPN | somatic clone,dendrite & DC3 adPN | somatic clone,dendrite & DA1 lPN | somatic clone,axon & DL1 adPN | somatic clone,trichogen cell,mesothoracic tergum" DRSC27821 K 0.491534514 0.130321684 -0.114528858 0.80390217 1.752152644 1.249595283 FBgn0001884 l(2)21Ba lethal (2) 21Ba http://flybase.org/reports/FBgn0001884 - gene - - - l(2)21Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011456 l(3)neo19 lethal (3) neo19 http://flybase.org/reports/FBgn0011456 - gene - - - l(3)neo19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263967 CR43723 - http://flybase.org/reports/FBgn0263967 non_protein_coding_gene - - - CR43723 - CR43723 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069089 rng rung http://flybase.org/reports/FBgn0069089 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available rng - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267147 CR45587 - http://flybase.org/reports/FBgn0267147 non_protein_coding_gene - - - CR45587 - CR45587 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263209 CR43379 - http://flybase.org/reports/FBgn0263209 pseudogene_attribute - - - CR43379 - CR43379 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026431 Grip75 Grip75 http://flybase.org/reports/FBgn0026431 FBgn0032257 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin binding ; GO:0043015 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 microtubule minus-end binding ; GO:0051011 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000447085 structural constituent of cytoskeleton ; GO:0005200 | non-traceable author statement male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 interphase microtubule nucleation by interphase microtubule organizing center ; GO:0051415 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 centrosome duplication ; GO:0051298 | inferred from mutant phenotype microtubule nucleation ; GO:0007020 | non-traceable author statement spindle assembly involved in female meiosis II ; GO:0007058 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 gamma-tubulin complex ; GO:0000930 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 equatorial microtubule organizing center ; GO:0000923 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin ring complex ; GO:0008274 | non-traceable author statement "Dgrip75, Dgrip75s, d75p, Dgrip75/d75p, 75p, CG6176, Grip75, DGrip75" IPR007259:Gamma-tubulin complex component protein CG6176 11-Aug-17 DroID_v2017_08 "Drer\tubgcp3, Drer\tubgcp2, Drer\tubgcp4" Scer\SPC98 - "Xtro\tubgcp4, Xtro\tubgcp3, Xtro\tubgcp2" "Mmus\Tubgcp3, Mmus\Tubgcp2, Mmus\Tubgcp4" "Hsap\TUBGCP4, Hsap\TUBGCP3, Hsap\TUBGCP2" "viable,fertile,female sterile,meiotic cell cycle defective,female,male,mitotic cell cycle defective,maternal effect" "ovariole,germline clone,egg,Nebenkern,spermatid,spindle,macrochaeta,adult cuticle,condensed chromosome,embryonic/larval neuroblast,mitotic spindle | third instar larval stage,spindle | cleavage stage | maternal effect,S2 cell-line" DRSC03337 K 1.138431599 -0.354598737 0.789786941 -0.332056775 1.683736745 0.049176276 FBgn0039941 CG17167 - http://flybase.org/reports/FBgn0039941 protein_coding_gene "calcium, potassium:sodium antiporter activity ; GO:0008273 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 sodium ion binding ; GO:0031402 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 potassium ion binding ; GO:0030955 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000090975" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 cellular calcium ion homeostasis ; GO:0006874 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 "CG17167, CG40146" "IPR004481:Sodium/potassium/calcium exchanger, IPR004837:Sodium/calcium exchanger membrane region" CG17167 11-Aug-17 DroID_v2017_08 "Drer\slc24a3, Drer\slc24a4b, Drer\slc24a4a, Drer\slc24a5, Drer\si:ch73-335m24.5, Drer\slc24a1, Drer\slc24a2" Scer\YDL206W Cele\ncx-2 "Xtro\slc24a5, Xtro\slc24a3, Xtro\slc24a2, Xtro\slc24a4" "Mmus\Slc24a3, Mmus\Slc24a2, Mmus\Slc24a5, Mmus\Slc24a4, Mmus\Slc24a1, Mmus\Slc8a2" "Hsap\SLC24A1, Hsap\SLC24A4, Hsap\SLC24A2, Hsap\SLC24A5, Hsap\SLC24A3, Hsap\SLC8A2" viable DRSC20903 I 1.70309004 -0.964260859 -0.374368677 -0.942154277 0.7301485 0.355667337 FBgn0263338 CR43419 - http://flybase.org/reports/FBgn0263338 non_protein_coding_gene - - - CR43419 - CR43419 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265557 12.167 - http://flybase.org/reports/FBgn0265557 gene - - - 12.167 - - 11-Aug-17 DroID_v2017_08 - - - - - - learning defective FBgn0039217 CG13627 - http://flybase.org/reports/FBgn0039217 protein_coding_gene - - - CG13627 - CG13627 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0030529 Clic Chloride intracellular channel http://flybase.org/reports/FBgn0030529 protein_coding_gene chloride channel activity ; GO:0005254 | inferred from direct assay calcium ion binding ; GO:0005509 | inferred from direct assay lipid binding ; GO:0008289 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay response to alcohol ; GO:0097305 | inferred from direct assay negative gravitaxis ; GO:0048060 | inferred from direct assay membrane ; GO:0016020 | inferred by curator from GO:0005254 nucleoplasm ; GO:0005654 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CLIC, CG10997, l(1)G0053, l(1)G0472, DCLIC, Clic, DmCLIC, clic" "IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG10997 11-Aug-17 DroID_v2017_08 "Drer\LOC100333907, Drer\clic5a, Drer\clic4, Drer\clic5b, Drer\clic1, Drer\clic3, Drer\clic2" - "Cele\exl-1, Cele\exc-4" "Xtro\clic5, Xtro\clic3, Xtro\clic6, Xtro\clic4, Xtro\clic1" "Mmus\Clic3, Mmus\Clic4, Mmus\Clic6, Mmus\Clic5, Mmus\Clic1" "Hsap\CLIC6, Hsap\CLIC1, Hsap\CLIC2, Hsap\CLIC5, Hsap\CLIC3, Hsap\CLIC4" "lethal,heat sensitive,gravitaxis defective,viable,fertile,partially lethal - majority die,male,female,recessive,visible" trichogen cell FBgn0010441 pll pelle http://flybase.org/reports/FBgn0010441 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 protein domain specific binding ; GO:0019904 | inferred from physical interaction with UniProtKB:P22812 protein kinase activity ; GO:0004672 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Tehao protein kinase activity ; GO:0004672 | non-traceable author statement" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype hemocyte proliferation ; GO:0035172 | traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 protein phosphorylation ; GO:0006468 | non-traceable author statement determination of dorsal/ventral asymmetry ; GO:0048262 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement apoptotic process ; GO:0006915 | non-traceable author statement innate immune response ; GO:0045087 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay hemopoiesis ; GO:0030097 | traceable author statement defense response ; GO:0006952 | traceable author statement response to fungus ; GO:0009620 | traceable author statement zygotic specification of dorsal/ventral axis ; GO:0007352 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay regulation of proteolysis ; GO:0030162 | traceable author statement antifungal humoral response ; GO:0019732 | inferred from mutant phenotype cytoplasm ; GO:0005737 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 cytoplasm ; GO:0005737 | inferred from direct assay "CG5974, PELLE/IL-1, p11, pll, pll/IRAK1, Pll" "IPR000488:Death domain, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011029:Death-like domain, IPR017441:Protein kinase, ATP binding site" CG5974 11-Aug-17 DroID_v2017_08 "Drer\irak3, Drer\ripk3, Drer\ankk1, Drer\ripk4, Drer\irak1, Drer\irak4, Drer\ripk2, Drer\pkdccb, Drer\pkdcca" "Scer\KIN1, Scer\ALK1, Scer\ALK2" Cele\pik-1 "Xtro\pkdcc.1, Xtro\ankk1, Xtro\ripk4, Xtro\irak4, Xtro\LOC100490493, Xtro\pkdcc.2, Xtro\irak2, Xtro\irak1" "Mmus\Ankk1, Mmus\Ripk3, Mmus\Ripk2, Mmus\Ripk1, Mmus\Irak4, Mmus\Pkdcc, Mmus\Irak2, Mmus\Ripk4, Mmus\Irak1, Mmus\Irak3" "Hsap\RIPK3, Hsap\IRAK3, Hsap\RIPK4, Hsap\ANKK1, Hsap\IRAK2, Hsap\RIPK2, Hsap\RIPK1, Hsap\IRAK1, Hsap\IRAK4, Hsap\PKDCC" " embryonic stage | early , larval stage && pupal stage , adult stage | female " "viable,fertile,lethal,maternal effect,cold sensitive,recessive,size defective,neuroanatomy defective,female sterile,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,heat sensitive" "embryonic ventral epidermis,embryonic/larval somatic muscle,macrochaeta,filzkorper,posterior spiracle primordium,medulla,lamina,axon & eye photoreceptor cell,hemocyte,embryonic/larval hemolymph,embryo,ventral" FBgn0260568 MENE(3R)-E - http://flybase.org/reports/FBgn0260568 gene - - - "MENE(3R)-E, MENE (3R)-E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye disc,somatic clone" FBgn0065103 snmRNA:173 small non-messenger RNA 173 http://flybase.org/reports/FBgn0065103 non_protein_coding_gene - - - "Dm-173, snmRNA:173" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005551 l(3)85Aj lethal (3) 85Aj http://flybase.org/reports/FBgn0005551 - gene - - - l(3)85Aj - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046297 CR9284 - http://flybase.org/reports/FBgn0046297 non_protein_coding_gene - - - "bs30g10.y1, BEST:GH11908, anon-WO0140519.157, CG9284, CR9284, Tes101" - CR9284 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002480 l(3)SG37 lethal (3) SG37 http://flybase.org/reports/FBgn0002480 FBgn0004720 gene - - - "l(3)ds6, l(3)B6, l(3)SG37" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0060507 l(3)S104509a lethal (3) S104509a http://flybase.org/reports/FBgn0060507 gene - - - "1045/09, l(3)S104509a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025834 CG2879 - http://flybase.org/reports/FBgn0025834 - protein_coding_gene - - - "EG:25E8.6, CG2879" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025515 fs(3)82EFa fs(3)82EFa http://flybase.org/reports/FBgn0025515 - gene - - - fs(3)82EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0037060 CG10508 - http://flybase.org/reports/FBgn0037060 protein_coding_gene - - - CG10508 "IPR003892:Ubiquitin system component Cue, IPR001202:WW domain, IPR009060:UBA-like" CG10508 11-Aug-17 DroID_v2017_08 "Drer\wwc1, Drer\wwc3" - - - "Mmus\Wwc2, Mmus\Wwc1" "Hsap\WWC1, Hsap\WWC2, Hsap\WWC3" "viable,fertile" FBgn0267696 CR46032 - http://flybase.org/reports/FBgn0267696 non_protein_coding_gene - - - CR46032 - CR46032 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037650 CG11977 - http://flybase.org/reports/FBgn0037650 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model CG11977 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain" CG11977 11-Aug-17 DroID_v2017_08 "Drer\crispld2, Drer\pi15b, Drer\r3hdml, Drer\crispld1b, Drer\pi15a, Drer\crispld1a" - "Cele\scl-1, Cele\scl-23, Cele\vap-2, Cele\scl-10, Cele\scl-20, Cele\scl-6" Xtro\crispld2 "Mmus\Pi15, Mmus\Crispld2, Mmus\Glipr1l1, Mmus\Clec18a, Mmus\Crispld1, Mmus\R3hdml, Mmus\Pi16" "Hsap\PI15, Hsap\CLEC18B, Hsap\CLEC18C, Hsap\R3HDML, Hsap\CLEC18A, Hsap\CRISPLD1, Hsap\GLIPR1L1, Hsap\CRISPLD2" viable FBgn0267815 CR46140 - http://flybase.org/reports/FBgn0267815 non_protein_coding_gene - - - CR46140 - CR46140 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037637 IscU Iron-sulfur cluster assembly enzyme http://flybase.org/reports/FBgn0037637 protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from biological aspect of ancestor with PANTHER:PTN000009661 ferrous iron binding ; GO:0008198 | inferred from biological aspect of ancestor with PANTHER:PTN000009661 iron-sulfur transferase activity ; GO:0036455 | inferred from biological aspect of ancestor with PANTHER:PTN000009661 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from biological aspect of ancestor with PANTHER:PTN000009661" "iron-sulfur cluster assembly ; GO:0016226 | inferred from electronic annotation with InterPro:IPR002871, InterPro:IPR011339 cellular iron ion homeostasis ; GO:0006879 | inferred from biological aspect of ancestor with PANTHER:PTN000009661 protein maturation by iron-sulfur cluster transfer ; GO:0097428 | inferred from biological aspect of ancestor with PANTHER:PTN000009661" mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000009663 "Isu1, fIscU, CG9836, IscU, dIscU, iscu" "IPR002871:NIF system FeS cluster assembly, NifU, N-terminal, IPR011339:ISC system FeS cluster assembly, IscU scaffold" CG9836 11-Aug-17 DroID_v2017_08 "Drer\iscub, Drer\si:ch211-191d15.2" "Scer\ISU1, Scer\ISU2" Cele\Y45F10D.4 Xtro\iscu Mmus\Iscu Hsap\ISCU "lethal - all die before end of pupal stage,some die during pupal stage,lethal,locomotor rhythm defective" DRSC16572 E -0.400850823 -0.577537775 -2.099001167 0.884902627 -0.385590337 1.367624983 FBgn0000197 Ble Bar-like eye http://flybase.org/reports/FBgn0000197 - gene - - - Ble - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" eye FBgn0019760 l(1)74 lethal (1) 74 http://flybase.org/reports/FBgn0019760 - gene - - - l(1)74 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029865 CG15893 - http://flybase.org/reports/FBgn0029865 protein_coding_gene - - - "BEST:LD05774, CG15893" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267019 CR45463 - http://flybase.org/reports/FBgn0267019 non_protein_coding_gene - - - CR45463 - CR45463 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260997 CG42598 - http://flybase.org/reports/FBgn0260997 protein_coding_gene - - - CG42598 "IPR004302:Cellulose/chitin-binding protein, N-terminal" CG42598 11-Aug-17 DroID_v2017_08 - - - - Mmus\Defb46 - FBgn0053309 CG33309 - http://flybase.org/reports/FBgn0053309 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "DS06874.7, BG:DS06874.7, NEST:bs22a11, CG33309" - CG33309 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050299 tRNA:Thr-AGT-1-2 transfer RNA:Threonine-AGT 1-2 http://flybase.org/reports/FBgn0050299 tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "CR30299, AE002787.trna27-ThrAGT, tRNA[Thr][[3]], tRNA:thr3:47F, tRNA:T3:47F, tRNA:T:AGT:AE002787-a, tRNA[[Thr]], chr2R.trna86-ThrAGT, tRNA-Thr-AGT-1-2, tRNA:Thr-AGT-1-2, tRNA:CR30299, ACU" - CR30299 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037901 CG6744 - http://flybase.org/reports/FBgn0037901 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002562, InterPro:IPR012337 3'-5' exonuclease activity ; GO:0008408 | inferred from biological aspect of ancestor with PANTHER:PTN000341301 3'-5' exonuclease activity ; GO:0008408 | inferred from sequence or structural similarity with HGNC:12791" somatic cell DNA recombination ; GO:0016444 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000341338 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000341338 CG6744 "IPR002562:3'-5' exonuclease domain, IPR012337:Ribonuclease H-like domain" CG6744 11-Aug-17 DroID_v2017_08 "Drer\exd2, Drer\wrn" - Cele\egal-1 "Xtro\exd2, Xtro\wrn" "Mmus\Exd2, Mmus\Wrn" "Hsap\WRN, Hsap\EXD2" "viable,fertile" FBgn0015515 mpt-1 mpt-1 http://flybase.org/reports/FBgn0015515 - gene - - - mpt-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036397 Nprl3 Nitrogen permease regulator-like 3 http://flybase.org/reports/FBgn0036397 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Nprl2 negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype TORC1 signaling ; GO:0038202 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from genetic interaction with mio inferred from genetic interaction with Nup44A negative regulation of TORC1 signaling ; GO:1904262 | inferred from mutant phenotype inferred from genetic interaction with Wdr24 negative regulation of TORC1 signaling ; GO:1904262 | inferred from mutant phenotype regulation of autophagosome assembly ; GO:2000785 | inferred from biological aspect of ancestor with PANTHER:PTN000994527 cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype positive regulation of macroautophagy ; GO:0016239 | inferred from genetic interaction with Wdr24 negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay Iml1 complex ; GO:1990130 | traceable author statement autolysosome ; GO:0044754 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000001015 Seh1-associated complex ; GO:0035859 | inferred from direct assay GATOR2 complex ; GO:0061700 | inferred from direct assay "nprl3, Nprl3, CG8783, NPR3, Nplr3" IPR005365:Nitrogen permease regulator 3 CG8783 11-Aug-17 DroID_v2017_08 Drer\nprl3 Scer\NPR3 Cele\nprl-3 Xtro\nprl3 Mmus\Nprl3 Hsap\NPRL3 viable FBgn0016988 oho48E overgrown hematopoietic organs 48E http://flybase.org/reports/FBgn0016988 - gene - - - "l(2)131/17, l(2)k13117, oho48E" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051327 CG31327 - http://flybase.org/reports/FBgn0051327 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT17065, CG31327" "IPR031949:Domain of unknown function DUF4776, IPR031992:Domain of unknown function DUF4788" CG31327 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267692 CR46028 - http://flybase.org/reports/FBgn0267692 non_protein_coding_gene - - - CR46028 - CR46028 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266644 CR45151 - http://flybase.org/reports/FBgn0266644 non_protein_coding_gene - - - CR45151 - CR45151 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033781 CG13319 - http://flybase.org/reports/FBgn0033781 protein_coding_gene - proteasome assembly ; GO:0043248 | inferred from electronic annotation with InterPro:IPR032157 proteasome complex ; GO:0000502 | colocalizes_with inferred from direct assay "BcDNA:GH19585, CG13319" IPR032157:Proteasome assembly chaperone 4 CG13319 11-Aug-17 DroID_v2017_08 Drer\psmg4 - - - Mmus\Psmg4 Hsap\PSMG4 "viable,fertile" FBgn0011293 a10 antennal protein 10 http://flybase.org/reports/FBgn0011293 FBgn0010402 protein_coding_gene - - extracellular region ; GO:0005576 | inferred from sequence model "OS-D/A10, Phk-1, A10, OS-D, Os-D, CG6642, a10, DmelCSP4" IPR005055:Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 CG6642 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " sacculus

, sensillum coeloconica of antennal segment 3

, antennal segment 3

" viable DRSC11319 E -0.041920829 -0.478821419 -1.706871378 -0.020651462 -0.406337912 0.270568887 FBgn0264428 CR43846 - http://flybase.org/reports/FBgn0264428 non_protein_coding_gene - - - CR43846 - CR43846 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085312 CG34283 - http://flybase.org/reports/FBgn0085312 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG34283 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type, IPR022776:TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG34283 11-Aug-17 DroID_v2017_08 "Drer\LOC100535654, Drer\zgc:56699" - Cele\T06A10.3 Xtro\LOC100145274 "Mmus\Gtsf1, Mmus\Gtsf1l, Mmus\BC048502, Mmus\Zfp850" "Hsap\GTSF1, Hsap\GTSF1L" FBgn0032614 CG13284 - http://flybase.org/reports/FBgn0032614 protein_coding_gene - Golgi organization ; GO:0007030 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG13284 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG13284 11-Aug-17 DroID_v2017_08 "Drer\hsd17b12a, Drer\hsd17b3, Drer\hsd20b2, Drer\hsd17b12b, Drer\hsdl1" Scer\IFA38 "Cele\dhs-27, Cele\stdh-4, Cele\stdh-3, Cele\dhs-5, Cele\stdh-2, Cele\stdh-1, Cele\let-767" "Xtro\LOC100497556, Xtro\hsd17b12, Xtro\hsdl1" "Mmus\Hsd17b12, Mmus\Hsdl1, Mmus\Hsd17b3" "Hsap\HSDL1, Hsap\HSD17B3, Hsap\HSD17B12" FBgn0065376 l(2)SH1677 lethal (2) SH1677 http://flybase.org/reports/FBgn0065376 gene - - - "l(2)SH1677, l(2)SH2 1677" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030360 CG1806 - http://flybase.org/reports/FBgn0030360 protein_coding_gene - - integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR030429 dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from electronic annotation with InterPro:IPR030429 CG1806 IPR030429:Sarcospan CG1806 11-Aug-17 DroID_v2017_08 Drer\sspn - - - Mmus\Sspn Hsap\SSPN viable FBgn0069172 mcl(3)Z0375 mcl(3)Z0375 http://flybase.org/reports/FBgn0069172 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z0375 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0262425 mir-288 mir-288 stem loop http://flybase.org/reports/FBgn0262425 miRNA_gene - - - "mir-288, CR42978, miR-288, Mir-288, CR33604" - CR42978 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065610 l(2)SH0838 lethal (2) SH0838 http://flybase.org/reports/FBgn0065610 gene - - - "l(2)SH0838, l(2)SH2 0838" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065095 snmRNA:400 small non-messenger RNA 400 http://flybase.org/reports/FBgn0065095 non_protein_coding_gene - - - "Dm-400, CR33699, snmRNA:400" - CR33699 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028910 tRNA:Pro-AGG-1-4 transfer RNA:Proline-AGG 1-4 http://flybase.org/reports/FBgn0028910 tRNA_gene CCU codon-amino acid adaptor activity ; GO:0033421 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033421 cytosol ; GO:0005829 | inferred by curator from GO:0033421 "BG:DS01486.4, tRNA:pro, AE002690.trna12-ProAGG, tRNA:P:AGG:AE002690-c, CR31984, chr2L.trna21-ProAGG, tRNA-Pro-AGG-1-4, tRNA:Pro-AGG-1-4, tRNA:P:35Bc, CCU" - CR31984 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041250 Gr21a Gustatory receptor 21a http://flybase.org/reports/FBgn0041250 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 detection of carbon dioxide ; GO:0003031 | inferred from genetic interaction with Gr21a response to carbon dioxide ; GO:0010037 | inferred from genetic interaction with Gr63a sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "CG13948, Gr21D1, 21D.1, GR21D.1, Gr21a, (GR) 21a, GR21D1, DmGr21a, GR21a, gr21a" IPR013604:7TM chemoreceptor CG13948 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - DRSC00366 I 0.434181583 1.894095298 -0.087036894 0.457783959 -1.042821811 -0.207048129 FBgn0069996 BG01740 BG01740 http://flybase.org/reports/FBgn0069996 gene - - - BG01740 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0027524 CG3909 - http://flybase.org/reports/FBgn0027524 - protein_coding_gene - - - "BcDNA:LD21537, CG3909, Ski8, CG3039, dSki8" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG3909 11-Aug-17 DroID_v2017_08 "Drer\LOC100332173, Drer\wdr61, Drer\wdr7, Drer\apaf1" "Scer\SKI8, Scer\PRP4, Scer\CAF4, Scer\SIF2, Scer\TEX1" Cele\B0280.9 "Xtro\apaf1, Xtro\wdr61, Xtro\tep1, Xtro\wdr38" "Mmus\Wdr61, Mmus\Apaf1, Mmus\Wdr53, Mmus\Dcaf10, Mmus\Tep1" "Hsap\TEP1, Hsap\WDR61, Hsap\APAF1, Hsap\WDR53" viable "wing,posterior compartment" FBgn0085745 CR40565 - http://flybase.org/reports/FBgn0085745 rRNA_gene - - - CR40565 - CR40565 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027102 su(N) su(N) http://flybase.org/reports/FBgn0027102 - gene - - - "su-co, su(N)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025143 ms(3)A4 ms(3)A4 http://flybase.org/reports/FBgn0025143 - gene - - - ms(3)A4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0037304 CG1113 - http://flybase.org/reports/FBgn0037304 protein_coding_gene - - - CG1113 - CG1113 11-Aug-17 DroID_v2017_08 Drer\fam161a - - Xtro\fam161a Mmus\Fam161a Hsap\FAM161A "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0266401 CR45041 - http://flybase.org/reports/FBgn0266401 non_protein_coding_gene - - - CR45041 - CR45041 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032068 LManV Lysosomal alpha-mannosidase V http://flybase.org/reports/FBgn0032068 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR015341 alpha-mannosidase activity ; GO:0004559 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 mannose metabolic process ; GO:0006013 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 protein deglycosylation ; GO:0006517 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 - "LManV, CG9466" "IPR000602:Glycoside hydrolase family 38, N-terminal domain, IPR011013:Galactose mutarotase-like domain, IPR011682:Glycosyl hydrolase family 38, C-terminal, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR015341:Glycoside hydrolase family 38, central domain, IPR027291:Glycoside hydrolase 38/57, N-terminal domain, IPR028995:Glycoside hydrolase families 57/38, central domain" CG9466 11-Aug-17 DroID_v2017_08 "Drer\man2b1, Drer\man2a1, Drer\man2b2, Drer\man2a2" - Cele\aman-1 "Xtro\man2b2, Xtro\man2b1, Xtro\man2a2, Xtro\man2a1" "Mmus\Man2a1, Mmus\Man2b1, Mmus\Man2b2" "Hsap\MAN2A2, Hsap\MAN2B1, Hsap\MAN2A1, Hsap\MAN2B2" viable FBgn0024341 KH4-2 KH domain cDNA KH4-2 http://flybase.org/reports/FBgn0024341 - gene - - - KH4-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067071 Mmap370 microtuble/microfilament-associated protein 370 http://flybase.org/reports/FBgn0067071 gene - - - "MMAP370, Mmap370" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051251 CG31251 - http://flybase.org/reports/FBgn0051251 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000270240 developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN000270240 nuclear migration ; GO:0007097 | inferred from sequence or structural similarity with RGD:3215 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000270240 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000270240 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with RGD:3215 "CG7477, CG31251, NudC-L" "IPR025934:NudC N-terminal domain, IPR007052:CS domain, IPR008978:HSP20-like chaperone, IPR027761:NudC domain-containing protein 3" CG31251 11-Aug-17 DroID_v2017_08 "Drer\zgc:56576, Drer\nudcd2, Drer\nudcd3, Drer\nudc" - Cele\nud-1 "Xtro\c14orf166, Xtro\nudcd2, Xtro\nudc, Xtro\nudcd3" "Mmus\Nudcd3, Mmus\2700060E02Rik, Mmus\Nudc, Mmus\Nudcd2" "Hsap\NUDCD2, Hsap\NUDCD3, Hsap\C14orf166, Hsap\NUDC" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0259233 CG42331 - http://flybase.org/reports/FBgn0259233 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 - "CG42331, CG13632, CG6879" "IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal" CG42331 11-Aug-17 DroID_v2017_08 "Drer\tpo, Drer\ptgs2a, Drer\ptgs2b, Drer\ptgs1, Drer\igsf9bb" - "Cele\R08F11.7, Cele\T06D8.10, Cele\F09F3.5, Cele\C46A5.4, Cele\K10B4.1" "Xtro\ptgs2, Xtro\ptgs1, Xtro\epx, Xtro\pxdn, Xtro\tpo, Xtro\mpo" "Mmus\Mpo, Mmus\Epx, Mmus\Lpo, Mmus\Ptgs2, Mmus\Ptgs1, Mmus\Tpo, Mmus\Pxdn" "Hsap\LPO, Hsap\EPX, Hsap\PTGS2, Hsap\MPO, Hsap\PTGS1, Hsap\PXDN, Hsap\TPO, Hsap\PXDNL" """DRSC25930, DRSC16126"" " K 0.428453235 0.140144903 0.327253052 0.671705967 2.159999039 0.723259226 FBgn0019771 l(1)48 lethal (1) 48 http://flybase.org/reports/FBgn0019771 - gene - - - l(1)48 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034927 CG17656 - http://flybase.org/reports/FBgn0034927 protein_coding_gene - - - CG17656 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000177 bh baldhead http://flybase.org/reports/FBgn0000177 - gene - - - bh - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,female sterile" "ocellus,ocellar bristle,wing" FBgn0014307 l(3)neo58a lethal (3) neo58a http://flybase.org/reports/FBgn0014307 - gene - - - l(3)neo58a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001615 l(1)dd11 lethal (1) discs degenerate 11 http://flybase.org/reports/FBgn0001615 - gene - - - "d.deg.-11, l(1)d.deg.-11, l(1)d deg11, l(1)d deg-11, l(1)d.deg.11, l(1)dd11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0020514 A35 A35 http://flybase.org/reports/FBgn0020514 - gene - - - A35 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002874 mudl mudlike http://flybase.org/reports/FBgn0002874 - gene - - - "mud, mudl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective" pigment cell FBgn0013775 DNA-ligII DNA ligase II http://flybase.org/reports/FBgn0013775 FBgn0004596 gene DNA ligase (ATP) activity ; GO:0003910 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay DNA-ligII - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029912 CG4557 - http://flybase.org/reports/FBgn0029912 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from sequence or structural similarity with SGD:S000003895 biological_process ; GO:0008150 | no biological data available Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with SGD:S000003895 "CG4557, AAF46211" "IPR022091:TATA element modulatory factor 1 TATA binding, IPR022092:TATA element modulatory factor 1 DNA binding" CG4557 11-Aug-17 DroID_v2017_08 Drer\tmf1 Scer\SGM1 - Xtro\tmf1 Mmus\Tmf1 Hsap\TMF1 FBgn0000131 Ars-region9 Autonomous replicating sequence region 9 http://flybase.org/reports/FBgn0000131 - region - - - "ars414, Ars-region9, Ars9" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052263 CG32263 - http://flybase.org/reports/FBgn0052263 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 "CG10854, CG32263" IPR007248:Mpv17/PMP22 CG32263 11-Aug-17 DroID_v2017_08 "Drer\mpv17l2, Drer\pxmp2, Drer\si:ch211-120k19.1, Drer\mpv17" "Scer\SYM1, Scer\YOR292C" Cele\ZK470.1 "Xtro\mpv17l2, Xtro\pxmp2" "Mmus\Mpv17, Mmus\Pxmp2, Mmus\Mpv17l2, Mmus\Mpv17l" "Hsap\MPV17L2, Hsap\MPV17, Hsap\PXMP2, Hsap\MPV17L" partially lethal - majority die FBgn0032399 CG6785 - http://flybase.org/reports/FBgn0032399 protein_coding_gene - - - "CG6785, cg6785" IPR015943:WD40/YVTN repeat-like-containing domain CG6785 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0259346 C56 - http://flybase.org/reports/FBgn0259346 gene - - - C56 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing,chaeta" FBgn0069948 CG41075 - http://flybase.org/reports/FBgn0069948 protein_coding_gene - - - CG41075 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065458 l(2)SH1384 lethal (2) SH1384 http://flybase.org/reports/FBgn0065458 gene - - - "l(2)SH1384, l(2)SH2 1384" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010149 l(3)DTS-I165 lethal (3) DTS-I165 http://flybase.org/reports/FBgn0010149 - gene - - - "DTS-I165, l(3)DTS-I165" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive" FBgn0033208 mRpL52 mitochondrial ribosomal protein L52 http://flybase.org/reports/FBgn0033208 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P0C2B7 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with protein_id:BAB23216 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | inferred from electronic annotation with InterPro:IPR034596 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P0C2B7 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:P0C2B7 inferred from sequence or structural similarity with UniProtKB:Q86TS9 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with protein_id:BAB23216 "MRP-L52, CG1577, BcDNA:RH01479, mRpL52, rpl52, rpl-52" "IPR034596:39S ribosomal protein L52, mitochondrial" CG1577 11-Aug-17 DroID_v2017_08 Drer\mrpl52 - - - Mmus\Mrpl52 Hsap\MRPL52 "viable,visible" trichogen cell FBgn0030674 CG8184 - http://flybase.org/reports/FBgn0030674 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:30892 dsRNA transport ; GO:0033227 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:30892 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:30892 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:30892 "URE-B1/CG8184, CG8184" "IPR025527:Domain of unknown function DUF4414, IPR000569:HECT domain, IPR004170:WWE domain, IPR010309:E3 ubiquitin ligase, domain of unknown function DUF908, IPR010314:E3 ubiquitin ligase, domain of unknown function DUF913, IPR015940:Ubiquitin-associated domain, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR009060:UBA-like" CG8184 11-Aug-17 DroID_v2017_08 "Drer\hace1, Drer\arel1, Drer\huwe1" Scer\TOM1 Cele\eel-1 "Xtro\arel1, Xtro\hace1, Xtro\huwe1, Xtro\hectd3" "Mmus\Arel1, Mmus\Hace1, Mmus\Huwe1, Mmus\Hectd3" "Hsap\AREL1, Hsap\HACE1, Hsap\HECTD3, Hsap\HUWE1" "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0003554 Su(Cy) Suppressor of Curly http://flybase.org/reports/FBgn0003554 - gene - - - Su(Cy) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066362 jack jack http://flybase.org/reports/FBgn0066362 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available jack - - 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,chemical sensitive" FBgn0051080 TwdlH TweedleH http://flybase.org/reports/FBgn0051080 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from direct assay chitin-based cuticle development ; GO:0040003 | inferred from expression pattern proteinaceous extracellular matrix ; GO:0005578 | inferred from direct assay "CG14241, TwdlH, CG31080" IPR004145:Domain of unknown function DUF243 CG31080 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0061081 l(3)S013904 lethal (3) S013904 http://flybase.org/reports/FBgn0061081 gene - - - "0139/04, l(3)S013904" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0035714 CG8549 - http://flybase.org/reports/FBgn0035714 protein_coding_gene - mature ribosome assembly ; GO:0042256 | inferred from electronic annotation with InterPro:IPR002140 - CG8549 "IPR018023:Ribosome maturation protein SBDS, conserved site, IPR002140:Ribosome maturation protein Sdo1/SBDS, IPR018978:Ribosome maturation protein SBDS, C-terminal, IPR019783:Ribosome maturation protein SBDS, N-terminal" CG8549 11-Aug-17 DroID_v2017_08 Drer\sbds "Scer\SDO1, Scer\RTC3" Cele\sbds-1 Xtro\sbds Mmus\Sbds Hsap\SBDS viable FBgn0264080 T:SS-boss Signal sequence of boss http://flybase.org/reports/FBgn0264080 engineered_tag - - - T:SS-boss - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037689 CG8135 - http://flybase.org/reports/FBgn0037689 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8135 IPR006876:LMBR1-like membrane protein CG8135 11-Aug-17 DroID_v2017_08 "Drer\lmbrd2a, Drer\lmbrd2b" - Cele\C47G2.4 Xtro\lmbrd2 Mmus\Lmbrd2 Hsap\LMBRD2 viable FBgn0085706 CG41580 - http://flybase.org/reports/FBgn0085706 protein_coding_gene - - - CG41580 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052983 CG32983 - http://flybase.org/reports/FBgn0052983 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18663, CG32983" - CG32983 11-Aug-17 DroID_v2017_08 - - "Cele\ZC13.2, Cele\srz-67" - - - viable FBgn0015575 alpha-Est7 alpha-Esterase-7 http://flybase.org/reports/FBgn0015575 "FBgn0004945, FBgn0020634, FBgn0020658" protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay inferred from mutant phenotype response to organophosphorus ; GO:0046683 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "alphaE7, EST23, aE7, H, ali, Est23, alpha-Est7, Mce, Est-23, CG1112, Ali, DmalphaE7, alphaest-7, alpha-Esterase-7, Alpha-Est7" "IPR002018:Carboxylesterase, type B, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG1112 11-Aug-17 DroID_v2017_08 "Drer\nlgn2a, Drer\nlgn3a, Drer\nlgn4b, Drer\cel.1, Drer\nlgn1, Drer\nlgn2b, Drer\nlgn3b, Drer\si:ch211-93f2.1, Drer\ces3, Drer\ces2, Drer\nlgn4a, Drer\cell" - "Cele\Y71H2AM.13, Cele\T28C12.5, Cele\F56C11.6, Cele\B0238.1, Cele\K11G9.1, Cele\K11G9.3, Cele\C52A10.2, Cele\F13H6.3, Cele\R173.3, Cele\F15A8.6, Cele\B0238.7, Cele\T28C12.4, Cele\T07H6.1, Cele\C52A10.1, Cele\F07C4.12, Cele\K11G9.2" "Xtro\cel, Xtro\nlgn4x, Xtro\ces2, Xtro\ces3, Xtro\nlgn2, Xtro\LOC100494782, Xtro\nlgn3" "Mmus\Ces3a, Mmus\Ces3b, Mmus\Ces2b, Mmus\Ces2a, Mmus\Ces2h, Mmus\Nlgn3, Mmus\Ces1c, Mmus\Ces1b, Mmus\Nlgn2, Mmus\Ces2g, Mmus\Ces2f, Mmus\Ces4a, Mmus\Ces1g, Mmus\Cel, Mmus\Ces1e, Mmus\Ces1d, Mmus\Nlgn1, Mmus\Ces1h, Mmus\Ces5a, Mmus\Ces2e, Mmus\Ces2c, Mmus\Ces1f" "Hsap\CES1, Hsap\NLGN1, Hsap\NLGN2, Hsap\NLGN4Y, Hsap\NLGN3, Hsap\CES4A, Hsap\CES5A, Hsap\NLGN4X, Hsap\CES3, Hsap\CEL, Hsap\CES2" "chemical resistant,chemical sensitive,short lived,viable,electrophoretic variant" FBgn0035955 CG5194 - http://flybase.org/reports/FBgn0035955 protein_coding_gene - - - "anon-WO0140519.239, CG5194" - CG5194 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020284 l(3)08034 lethal (3) 08034 http://flybase.org/reports/FBgn0020284 - gene - - - "8034, l(3)08034" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052141 CG32141 - http://flybase.org/reports/FBgn0052141 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32141 - CG32141 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028039 l(3)S100201 lethal (3) S100201 http://flybase.org/reports/FBgn0028039 gene - - - "1002/01, l(3)S100201" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085653 CG41492 - http://flybase.org/reports/FBgn0085653 protein_coding_gene - - - CG41492 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044426 M80-11 M80-11 http://flybase.org/reports/FBgn0044426 gene molecular_function ; GO:0003674 | no biological data available eye photoreceptor cell differentiation ; GO:0001754 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "M80#11, M80-11" - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0035691 CG7386 - http://flybase.org/reports/FBgn0035691 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 CG7386 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7386 11-Aug-17 DroID_v2017_08 "Drer\znf341, Drer\zgc:162948, Drer\znf770, Drer\znf668" - "Cele\eor-1, Cele\Y37F4.6, Cele\sem-4" Xtro\znf668 "Mmus\Zfp341, Mmus\Zfp668" "Hsap\ZNF668, Hsap\ZNF284, Hsap\ZNF341, Hsap\ZNF44, Hsap\ZNF221" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0033312 CG8642 - http://flybase.org/reports/FBgn0033312 protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from sequence or structural similarity with HGNC:3623 chitin binding ; GO:0008061 | inferred from sequence or structural similarity with HGNC:25922 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with HGNC:3623 membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:25922 "CG8642, AAF59068, FBpp0087808" "IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR020837:Fibrinogen, conserved site, IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain" CG8642 11-Aug-17 DroID_v2017_08 "Drer\si:zfos-2330d3.1, Drer\angpt2a, Drer\angpt2b, Drer\si:ch211-157b11.8, Drer\angptl6, Drer\angpt4, Drer\fga, Drer\si:ch211-203k16.3, Drer\fgl1, Drer\tnw, Drer\si:dkeyp-51b7.3, Drer\fibcd1, Drer\angpt1, Drer\tnxba, Drer\angptl1a, Drer\LOC555374, Drer\si:ch211-287a12.9, Drer\si:zfos-2330d3.6, Drer\mfap4, Drer\wu:fj11g02, Drer\angptl2b, Drer\LOC100007488, Drer\tnc, Drer\angptl2a, Drer\fgl2b, Drer\angptl7, Drer\angptl5, Drer\si:zfos-2330d3.3, Drer\si:ch1073-110a20.2, Drer\zgc:171687, Drer\si:ch1073-110a20.1, Drer\zmp:0000000846, Drer\fgg, Drer\zgc:194887, Drer\angptl4, Drer\zgc:173915, Drer\angptl3, Drer\si:zfos-2330d3.8, Drer\si:ch1073-110a20.3, Drer\fgb, Drer\tnr, Drer\fgl2a" Scer\SMC1 "Cele\Y26D4A.12, Cele\eea-1, Cele\ZC504.1, Cele\Y69H2.10, Cele\T15B7.1, Cele\ensh-1, Cele\K10D3.4, Cele\C08G9.2, Cele\Y43C5A.2, Cele\Y69H2.3, Cele\W05B2.2" "Xtro\angptl3, Xtro\angptl5, Xtro\angptl4, Xtro\LOC100497330, Xtro\tnn, Xtro\fcn3, Xtro\angptl2, Xtro\LOC100491105, Xtro\fcn1, Xtro\tnxb, Xtro\fgb, Xtro\fibcd1, Xtro\tnr, Xtro\tnc, Xtro\fcn2, Xtro\LOC100488177, Xtro\angptl7, Xtro\fgg, Xtro\fga, Xtro\fgl2, Xtro\fgl1, Xtro\angpt4, Xtro\mfap4, Xtro\angpt1" "Mmus\Fgl2, Mmus\Tnxb, Mmus\Angpt4, Mmus\Angpt2, Mmus\Angptl7, Mmus\Angptl2, Mmus\Fcna, Mmus\Tnr, Mmus\Fgb, Mmus\Angptl3, Mmus\Angptl1, Mmus\Mfap4, Mmus\Fgg, Mmus\Angpt1, Mmus\Tnc, Mmus\Fgl1, Mmus\Tnn, Mmus\Angptl6, Mmus\Fga, Mmus\Fibcd1, Mmus\Angptl4, Mmus\Fcnb" "Hsap\TNR, Hsap\ANGPTL4, Hsap\MFAP4, Hsap\FGA, Hsap\TNC, Hsap\TNN, Hsap\FGL1, Hsap\ANGPT4, Hsap\ANGPTL1, Hsap\FIBCD1, Hsap\FCN3, Hsap\ANGPT1, Hsap\FCN2, Hsap\ANGPTL5, Hsap\FGL2, Hsap\ANGPTL2, Hsap\ANGPT2, Hsap\ANGPTL7, Hsap\FCN1, Hsap\TNXB, Hsap\FGB, Hsap\ANGPTL3, Hsap\ANGPTL6, Hsap\FGG" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0030487 CG12726 - http://flybase.org/reports/FBgn0030487 protein_coding_gene - - - CG12726 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014920 anon-72ABd anon-72ABd http://flybase.org/reports/FBgn0014920 - gene - - - anon-72ABd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029040 l(2)F32 lethal (2) F32 http://flybase.org/reports/FBgn0029040 gene - - - "F32, l(2)F32" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0017394 l(1)10Bs lethal (1) 10Bs http://flybase.org/reports/FBgn0017394 - gene - - - "HM22, l(1)10Bs" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001799 l(1)Mc1 lethal (1) Mc1 http://flybase.org/reports/FBgn0001799 - gene - - - l(1)Mc1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,size defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing,somatic clone,eye" FBgn0015982 l(2)PC4-H lethal (2) PC4-H http://flybase.org/reports/FBgn0015982 - gene - - - "l(2)PC4-K, l(2)PC4-H" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026217 l(3)06734 lethal (3) 06734 http://flybase.org/reports/FBgn0026217 - gene - - - l(3)06734 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004222 l(3)84Fj lethal (3) 84Fj http://flybase.org/reports/FBgn0004222 - gene - - - l(3)84Fj - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002969 nrs narrow scoop http://flybase.org/reports/FBgn0002969 - gene - - - nrs - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,female semi-sterile,male fertile,viable,male,female fertile,reduced,eye color defective,body color defective" "wing,macrochaeta,eye,pigment cell" FBgn0023118 anon-10Ap anon-10Ap http://flybase.org/reports/FBgn0023118 - gene - - - "8, anon-10Ap" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015747 Lcp11 Larval cuticle protein 11 http://flybase.org/reports/FBgn0015747 - gene - - - Lcp11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026383 Ori93Fbeta Ori93Fbeta http://flybase.org/reports/FBgn0026383 - origin_of_replication - - - "oriDbeta, Ori93Fbeta" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041131 l(2)45Ae lethal (2) 45Ae http://flybase.org/reports/FBgn0041131 gene - - - l(2)45Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0028048 l(3)S096404 lethal (3) S096404 http://flybase.org/reports/FBgn0028048 gene - - - "0964/04, l(3)S096404" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0263942 BG00218 - http://flybase.org/reports/FBgn0263942 gene - - - BG00218 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,female,male,heat stress response defective,starvation stress response defective,chemosensitive behavior defective" FBgn0262388 mir-92b mir-92b stem loop http://flybase.org/reports/FBgn0262388 miRNA_gene - larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype - "miR-92b, mir-92b, MIR-92, CR42916, CR33572, miR-92B, mIR-92b, dme-mir-92b, miR-92, dme-miR-92b" - CR42916 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,hypoactive,male" "wing,wing hair,wing sensillum,ectopic,embryonic/larval somatic muscle,A1-7 lateral transverse muscle,lateral transverse muscle,male" FBgn0259731 tal-2A tarsal-less 2A http://flybase.org/reports/FBgn0259731 protein_coding_gene molecular_function ; GO:0003674 | no biological data available morphogenesis of an epithelium ; GO:0002009 | inferred from genetic interaction with tal actin filament organization ; GO:0007015 | inferred from genetic interaction with tal cellular_component ; GO:0005575 | no biological data available "Dm2, tal-2A, CG42385, Pep2, ORF2, tal, ORF 2A, pri, Pri" - CG42385 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265000 CR44151 - http://flybase.org/reports/FBgn0265000 non_protein_coding_gene - - - CR44151 - CR44151 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086664 snoRNA:Psi28S-2149 snoRNA:Psi28S-2149 http://flybase.org/reports/FBgn0086664 snoRNA_gene - - - "snoRNA:143, psi28S-2149, Psi 28S-2149(SnoR143), snoR143, Psi28S-2149, snoRNA:Psi28S-2149, Dm-143, CR33776" - CR33776 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020543 l(1)18DEb lethal (1) 18DEb http://flybase.org/reports/FBgn0020543 - gene - - - l(1)18DEb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046712 GI GI http://flybase.org/reports/FBgn0046712 gene phospholipase A2 activity ; GO:0004623 | non-traceable author statement - extracellular region ; GO:0005576 | non-traceable author statement "dGI, GI" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000791 fs(1)de1 female sterile (1) defective eggs 1 http://flybase.org/reports/FBgn0000791 - gene - - - "de1, fs(1)de1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,partially,recessive,female sterile germline-dependent" "dorsal appendage,endochorion,chorion" FBgn0031740 CG7239 - http://flybase.org/reports/FBgn0031740 protein_coding_gene - - - "anon-EST:Posey250, CG7239" IPR026095:Myb/SANT-like DNA-binding domain-containing protein CG7239 11-Aug-17 DroID_v2017_08 Drer\msantd1 - - - Mmus\Msantd1 Hsap\MSANTD1 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0041111 lilli lilliputian http://flybase.org/reports/FBgn0041111 protein_coding_gene "DNA binding ; GO:0003677 | inferred from sequence or structural similarity with HGNC:6473 inferred from sequence or structural similarity with HGNC:7135 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:6473 inferred from sequence or structural similarity with HGNC:7135" "cell growth ; GO:0016049 | NOT inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype cell proliferation ; GO:0008283 | NOT inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from genetic interaction with Raf olfactory behavior ; GO:0042048 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | non-traceable author statement regulation of cytoskeleton organization ; GO:0051493 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | inferred from mutant phenotype periodic partitioning ; GO:0007365 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap regulation of lipid transport ; GO:0032368 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype periodic partitioning by pair rule gene ; GO:0007366 | inferred from mutant phenotype" transcriptionally active chromatin ; GO:0035327 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from direct assay ELL-EAF complex ; GO:0032783 | inferred from physical interaction with Su(Tpl) nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:6473 inferred from sequence or structural similarity with HGNC:7135 inferred from direct assay "lilli, CG8817, 189Y, 154454_at, Su(Raf)2A, SS2-1, SY2-1, l(2)23Cc, l(2)00632, Su(Raf)2a, l(2)K07920, l(2)K00632, BEST:GH09955, l(2)k16124, l(2)k07920, BcDNA:GM02019, S(ls)4, Lilli, AFF4, dAFF4" "IPR007797:Transcription factor AF4/FMR2, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical" CG8817 11-Aug-17 DroID_v2017_08 "Drer\aff4, Drer\aff2, Drer\aff3" - Cele\F43C11.9 "Xtro\aff1, Xtro\aff2, Xtro\aff4" "Mmus\Aff2, Mmus\Aff3, Mmus\Aff4, Mmus\Aff1" "Hsap\AFF2, Hsap\AFF1, Hsap\AFF3, Hsap\AFF4" "lethal,recessive,viable,smell perception defective,fertile,maternal effect,poor,wild-type,decreased cell size,somatic clone,terminal phenotype,germline clone,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,visible,pair rule phenotype,small body,memory defective,partially lethal - majority die" "embryonic/first instar larval cuticle,maternal effect,segment,eye photoreceptor cell,somatic clone,embryonic head,germline clone,embryonic segment,denticle belt,embryonic abdominal segment,cephalic furrow,extended germ band embryo,actin filament | embryonic stage | germline clone,yolk,lipid particle | germline clone,wing margin bristle,embryo,rhabdomere,cephalopharyngeal skeleton,anterior,filzkorper,embryonic epidermis,eye disc,eye,adult head,ommatidium" DRSC00708 IK 0.048651231 2.218757271 -0.296279498 -0.348312542 1.063191958 1.62912058 FBgn0262600 skf skiff http://flybase.org/reports/FBgn0262600 gene - - - skf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028531 CG15286 - http://flybase.org/reports/FBgn0028531 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 - - "BG:DS01068.11, CG15286" "IPR000433:Zinc finger, ZZ-type, IPR008598:Drought induced 19 protein type, zinc-binding domain" CG15286 11-Aug-17 DroID_v2017_08 Drer\kcmf1 - Cele\ZK652.6 Xtro\kcmf1 Mmus\Kcmf1 Hsap\KCMF1 viable FBgn0033915 CG8485 - http://flybase.org/reports/FBgn0033915 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 "152964_at, SNRK, CG8485" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG8485 11-Aug-17 DroID_v2017_08 "Drer\snrkb, Drer\nek4, Drer\snrka" "Scer\KIN1, Scer\GIN4, Scer\KCC4, Scer\KIN4, Scer\KIN2" Cele\ZK524.4 Xtro\snrk Mmus\Snrk Hsap\SNRK "partially lethal - majority die,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0011571 caz cabeza http://flybase.org/reports/FBgn0011571 "FBgn0003059, FBgn0011830, FBgn0062479" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "compound eye development ; GO:0048749 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013 larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11545 positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype" transcriptionally active chromatin ; GO:0035327 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11545 "TFIID, cas, CG3606, SARFH, P19, p19, pen19, anon-Pen19, Sarfh, Pen19, BcDNA:GM09207, caz, Caz, EWSR1, dFUS" "IPR000504:RNA recognition motif domain, IPR001876:Zinc finger, RanBP2-type" CG3606 11-Aug-17 DroID_v2017_08 "Drer\ewsr1a, Drer\fus, Drer\taf15, Drer\ewsr1b" - Cele\fust-1 "Xtro\cirbp, Xtro\fus, Xtro\ewsr1, Xtro\taf15" "Mmus\Rbm3, Mmus\Ewsr1, Mmus\Cirbp, Mmus\Taf15, Mmus\Fus" "Hsap\RBM3, Hsap\CIRBP, Hsap\FUS, Hsap\TAF15, Hsap\EWSR1" "wild-type,neuroanatomy defective,visible,locomotor behavior defective,progressive,gravitaxis defective,lethal,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,neurophysiology defective,viable,conditional,partially lethal - majority die" "embryonic/larval neuromuscular junction | third instar larval stage,eye,ommatidium,interommatidial bristle,embryonic/larval motor neuron | larval stage,NMJ bouton | larval stage,NMJ bouton | third instar larval stage,wing,conditional,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,ventral nerve cord | third instar larval stage,abdominal segment motor neuron | third instar larval stage,eye disc" FBgn0060772 l(3)S061318 lethal (3) S061318 http://flybase.org/reports/FBgn0060772 gene - - - "0613/18, l(3)S061318" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265489 BG01420 - http://flybase.org/reports/FBgn0265489 gene - - - BG01420 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060716 l(3)S069617 lethal (3) S069617 http://flybase.org/reports/FBgn0060716 gene - - - "0696/17, l(3)S069617" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040774 CG12922 - http://flybase.org/reports/FBgn0040774 protein_coding_gene - - - CG12922 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001573 l(1)55a lethal (1) 55a http://flybase.org/reports/FBgn0001573 - gene - - - "l(1)55, l(1)55a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" spermatogonium FBgn0031519 Fign Fidgetin http://flybase.org/reports/FBgn0031519 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 hydrolase activity ; GO:0016787 | inferred from sequence or structural similarity with UniProtKB:O16299 magnesium ion binding ; GO:0000287 | inferred from sequence or structural similarity with UniProtKB:O16299 microtubule-severing ATPase activity ; GO:0008568 | inferred from mutant phenotype" regulation of microtubule depolymerization ; GO:0031114 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype ATP metabolic process ; GO:0046034 | inferred from sequence or structural similarity with UniProtKB:O16299 microtubule severing ; GO:0051013 | inferred from mutant phenotype regulation of double-strand break repair via homologous recombination ; GO:0010569 | inferred from biological aspect of ancestor with PANTHER:PTN000553645 response to wounding ; GO:0009611 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 "DmCG3326, CG3326, Fign" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR015415:Vps4 oligomerisation, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3326 11-Aug-17 DroID_v2017_08 "Drer\LOC101884757, Drer\spast, Drer\fignl1, Drer\katnal2, Drer\iqca1, Drer\fign, Drer\katna1, Drer\vps4b, Drer\zgc:153738, Drer\si:dkey-157g16.6, Drer\katnal1" "Scer\YTA6, Scer\SAP1" "Cele\mei-1, Cele\vps-4, Cele\figl-1, Cele\spas-1" "Xtro\fignl1, Xtro\vps4a, Xtro\vps4b, Xtro\spast, Xtro\katna1, Xtro\fign" "Mmus\4931409K22Rik, Mmus\Spast, Mmus\Katnal1, Mmus\Fignl2, Mmus\Fign, Mmus\Vps4b, Mmus\Katna1, Mmus\Vps4a, Mmus\Fignl1, Mmus\Katnal2" "Hsap\IQCA1, Hsap\FIGN, Hsap\KATNA1, Hsap\SPAST, Hsap\KATNAL2, Hsap\FIGNL2, Hsap\VPS4A, Hsap\FIGNL1, Hsap\VPS4B, Hsap\KATNAL1" viable FBgn0033327 PGRP-SC1b Peptidoglycan recognition protein SC1b http://flybase.org/reports/FBgn0033327 protein_coding_gene N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from direct assay peptidoglycan binding ; GO:0042834 | traceable author statement peptidoglycan catabolic process ; GO:0009253 | inferred from direct assay innate immune response ; GO:0045087 | traceable author statement extracellular region ; GO:0005576 | inferred from sequence or structural similarity "pgrp-sc, CT8705, PGRP-SC1B, PGRP-SC, CG8577, SC1B, PGRP-SC1b, PGRP SC, PGRP-SC1, pgrp-sc1" - CG8577 11-Aug-17 DroID_v2017_08 "Drer\pglyrp2, Drer\pglyrp6, Drer\pglyrp5" - - "Xtro\pglyrp2, Xtro\pglyrp1, Xtro\pglyrp1" "Mmus\Pglyrp3, Mmus\Pglyrp2, Mmus\Pglyrp1, Mmus\Pglyrp4" "Hsap\PGLYRP2, Hsap\PGLYRP3, Hsap\PGLYRP4, Hsap\PGLYRP1" "viable,immune response defective" DRSC25294 K 1.912109246 -0.212964717 FBgn0053300 Muc30E Mucin 30E http://flybase.org/reports/FBgn0053300 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model biological_process ; GO:0008150 | no biological data available extracellular matrix ; GO:0031012 | inferred from sequence model "Muc30E, CG33300" - CG33300 11-Aug-17 DroID_v2017_08 Drer\muc13a - - - - - viable FBgn0003112 plo pillow http://flybase.org/reports/FBgn0003112 - gene - - - "pil, plo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" eye FBgn0035586 Fitm Fat storage inducing transmembrane protein http://flybase.org/reports/FBgn0035586 protein_coding_gene - lipid particle organization ; GO:0034389 | inferred from biological aspect of ancestor with PANTHER:PTN000565881 lipid storage ; GO:0019915 | inferred from biological aspect of ancestor with PANTHER:PTN000565881 sequestering of triglyceride ; GO:0030730 | inferred from sequence or structural similarity with MGI:MGI:2444508 phospholipid biosynthetic process ; GO:0008654 | inferred from biological aspect of ancestor with PANTHER:PTN000565881 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from sequence or structural similarity with MGI:MGI:2444508 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000565881 "i136, Fitm, CG10671, FIT2" IPR019388:Fat storage-inducing transmembrane protein CG10671 11-Aug-17 DroID_v2017_08 "Drer\fitm1, Drer\fitm2" "Scer\SCS3, Scer\YFT2" Cele\fitm-2 Xtro\fitm2 "Mmus\Fitm1, Mmus\Fitm2" "Hsap\FITM1, Hsap\FITM2" viable FBgn0038124 CG14380 - http://flybase.org/reports/FBgn0038124 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14380 - CG14380 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265825 CR44614 - http://flybase.org/reports/FBgn0265825 non_protein_coding_gene - - - CR44614 - CR44614 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053289 ppk5 pickpocket 5 http://flybase.org/reports/FBgn0053289 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG33289, ppk5" IPR001873:Epithelial sodium channel CG33289 11-Aug-17 DroID_v2017_08 "Drer\asic4b, Drer\asic4a, Drer\asic1a, Drer\asic2, Drer\asic1c, Drer\asic1b" - "Cele\flr-1, Cele\del-8, Cele\asic-1, Cele\acd-5, Cele\delm-1, Cele\unc-105, Cele\acd-2, Cele\del-6, Cele\delm-2, Cele\acd-4, Cele\acd-3, Cele\acd-1" "Xtro\asic1, Xtro\scnn1g, Xtro\scnn1a, Xtro\scnn1b, Xtro\scnn1d, Xtro\asic4, Xtro\asic5" "Mmus\Asic5, Mmus\Asic3, Mmus\Scnn1a, Mmus\Asic4, Mmus\Scnn1g, Mmus\Asic2, Mmus\Scnn1b, Mmus\Asic1" "Hsap\ASIC1, Hsap\ASIC3, Hsap\SCNN1A, Hsap\SCNN1D, Hsap\ASIC4, Hsap\ASIC5, Hsap\SCNN1G, Hsap\SCNN1B, Hsap\ASIC2" "viable,touch sensitivity defective,lethal" DRSC11492 I 0.134597336 1.540437654 -0.094975625 0.021572925 0.392436073 0.372081595 FBgn0261537 CG42661 - http://flybase.org/reports/FBgn0261537 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42661 - CG42661 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032400 CG6770 - http://flybase.org/reports/FBgn0032400 protein_coding_gene chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN001048453 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001048453 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001048453 "CT21019, anon-WO02059370.25, CG6770, p8" IPR018792:Nuclear protein 1-like CG6770 11-Aug-17 DroID_v2017_08 Drer\nupr1 - - - "Mmus\Nupr1, Mmus\Nupr1l" "Hsap\NUPR1, Hsap\NUPR2" "viable,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" DRSC02992 IEK -0.167034936 -5.187644813 -0.856982423 -6.256478003 -1.779807775 -1.148255143 FBgn0032454 CG5787 - http://flybase.org/reports/FBgn0032454 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay CG5787 - CG5787 11-Aug-17 DroID_v2017_08 "Drer\pih1d1, Drer\pih1d2" Scer\PIH1 Cele\grl-25 "Xtro\dnaaf2, Xtro\pih1d2, Xtro\pih1d1" "Mmus\Pih1d1, Mmus\Dnaaf2, Mmus\Pih1d2" "Hsap\DNAAF2, Hsap\PIH1D2, Hsap\PIH1D1" "viable,fertile,visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0004807 fs(2)ltoAHE1 female sterile (2) ltoAHE1 http://flybase.org/reports/FBgn0004807 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoAHE1 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0003976 vin vin http://flybase.org/reports/FBgn0003976 - gene - - - vin - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive,eye color defective,lethal" pigment cell FBgn0037827 CG4073 - http://flybase.org/reports/FBgn0037827 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG4073 - CG4073 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0027527 Osi6 Osiris 6 http://flybase.org/reports/FBgn0027527 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model endomembrane system ; GO:0012505 | inferred from direct assay "Osi6, CG1151, BcDNA:LD21503" IPR012464:Protein of unknown function DUF1676 CG1151 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037414 Osi7 Osiris 7 http://flybase.org/reports/FBgn0037414 protein_coding_gene molecular_function ; GO:0003674 | no biological data available lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi7, CG1153, osi7" IPR012464:Protein of unknown function DUF1676 CG1153 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0266958 CR45409 - http://flybase.org/reports/FBgn0266958 non_protein_coding_gene - - - CR45409 - CR45409 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001440 l(1)7Cb lethal (1) 7Cb http://flybase.org/reports/FBgn0001440 - gene - - - l(1)7Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,lethal - all die before end of larval stage,some die during larval stage" FBgn0038272 CG7265 - http://flybase.org/reports/FBgn0038272 protein_coding_gene molecular_function ; GO:0003674 | no biological data available peptidyl-diphthamide biosynthetic process from peptidyl-histidine ; GO:0017183 | inferred from sequence or structural similarity with SGD:S000001674 peptidyl-diphthamide biosynthetic process from peptidyl-histidine ; GO:0017183 | inferred from biological aspect of ancestor with PANTHER:PTN000079945 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000001674 CG7265 "IPR010014:Diphthamide synthesis DHP2, eukaryotic, IPR016435:Diphthamide synthesis DPH1/DPH2" CG7265 11-Aug-17 DroID_v2017_08 "Drer\dph1, Drer\dph2" "Scer\DPH2, Scer\DPH1" Cele\dph-2 Xtro\dph2 "Mmus\Dph2, Mmus\Dph1" "Hsap\DPH1, Hsap\DPH2" viable FBgn0030034 CG10555 - http://flybase.org/reports/FBgn0030034 protein_coding_gene ligand-dependent nuclear receptor transcription coactivator activity ; GO:0030374 | inferred from sequence or structural similarity with HGNC:11340 "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with RGD:621847" nucleus ; GO:0005634 | inferred from sequence or structural similarity with RGD:621847 CG10555 "IPR007726:SS18 family, IPR015943:WD40/YVTN repeat-like-containing domain" CG10555 11-Aug-17 DroID_v2017_08 "Drer\ss18, Drer\baz2a, Drer\ss18l2" Scer\AIM3 Cele\ZK973.9 "Xtro\ss18l1, Xtro\ss18l2, Xtro\ss18" "Mmus\Ss18l1, Mmus\Ss18, Mmus\Deb1" "Hsap\SS18L1, Hsap\SS18L2, Hsap\SS18" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0031093 CG9581 - http://flybase.org/reports/FBgn0031093 protein_coding_gene aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR007865 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR007865 - - CG9581 "IPR000994:Peptidase M24, IPR001714:Peptidase M24, methionine aminopeptidase, IPR007865:Aminopeptidase P, N-terminal, IPR029149:Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR028980:Creatinase/Aminopeptidase P, N-terminal" CG9581 11-Aug-17 DroID_v2017_08 "Drer\pepd, Drer\xpnpep3" "Scer\YFR006W, Scer\ICP55" "Cele\R119.2, Cele\K12C11.1, Cele\pqn-59" Xtro\xpnpep3 "Mmus\Pepd, Mmus\Xpnpep3" "Hsap\PEPD, Hsap\XPNPEP3, Hsap\RBX1" viable FBgn0262850 CR43214 - http://flybase.org/reports/FBgn0262850 pseudogene_attribute - - - "CR43214, noncoding_23159, noncoding_23161" - CR43214 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002094 l(2)57Bd lethal (2) 57Bd http://flybase.org/reports/FBgn0002094 - gene - - - l(2)57Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036373 Tgi Tondu-domain-containing Growth Inhibitor http://flybase.org/reports/FBgn0036373 protein_coding_gene transcription factor binding ; GO:0008134 | inferred from physical interaction with sd transcription coactivator binding ; GO:0001223 | inferred from physical interaction with yki "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay negative regulation of hippo signaling ; GO:0035331 | inferred from genetic interaction with sd inferred from genetic interaction with yki inferred from genetic interaction with hpo inferred from physical interaction with sd" nucleus ; GO:0005634 | inferred from direct assay "Tgi, NEST:bs23g10, CG10741, SdBP, tgi" "IPR006627:TDU repeat, IPR028184:Transcription cofactor vestigial-like protein 4" CG10741 11-Aug-17 DroID_v2017_08 "Drer\vgll4a, Drer\vgll4b, Drer\vgll4l" - Cele\R08C7.12 - Mmus\Vgll4 Hsap\VGLL4 "visible,size defective,lethal - all die before end of second instar larval stage,majority die during second instar larval stage,viable,body color defective,fertile" "eye disc,somatic clone,wing disc,wing,wing | adult stage,mesothoracic tergum" FBgn0022813 E(faf)E263 Enhancer of faf E263 http://flybase.org/reports/FBgn0022813 - gene - - - E(faf)E263 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" FBgn0069398 LRP Low Density Lipoprotein http://flybase.org/reports/FBgn0069398 gene - - - LRP - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259610 B1500 - http://flybase.org/reports/FBgn0259610 gene - - - B1500 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0259729 CG42383 - http://flybase.org/reports/FBgn0259729 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000596256 ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with RGD:619952 nuclear envelope reassembly ; GO:0031468 | inferred from biological aspect of ancestor with PANTHER:PTN000596257 membrane fusion ; GO:0061025 | inferred from biological aspect of ancestor with PANTHER:PTN000596257 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000596256 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000596257 nuclear envelope reassembly ; GO:0031468 | inferred from sequence or structural similarity with p47 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000596257 nucleus ; GO:0005634 | inferred from sequence or structural similarity with p47 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000596257 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with p47 "CG42383, CG4556, p47, eyc, p47 NSFL1, Eyc" "IPR009060:UBA-like, IPR012989:SEP domain, IPR001012:UBX domain, IPR029071:Ubiquitin-related domain" CG42383 11-Aug-17 DroID_v2017_08 "Drer\ubxn11, Drer\ubxn2a, Drer\nsfl1c" Scer\SHP1 Cele\ubxn-2 "Xtro\ubxn11, Xtro\ubxn2a" "Mmus\Ubxn2b, Mmus\Ubxn11, Mmus\Ubxn2a, Mmus\Nsfl1c" "Hsap\UBXN2B, Hsap\NSFL1C, Hsap\UBXN11, Hsap\UBXN2A" "visible,viable" "rhabdomere | heat sensitivehs.PB,endoplasmic reticulum | heat sensitivehs.PB,rhabdomereGMR.PF,mesothoracic tergum" FBgn0260718 CR42545 - http://flybase.org/reports/FBgn0260718 pseudogene_attribute - - - CR42545 - CR42545 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010039 GstD3 Glutathione S transferase D3 http://flybase.org/reports/FBgn0010039 "FBgn0038022, FBgn0063086" protein_coding_gene glutathione transferase activity ; GO:0004364 | non-traceable author statement glutathione transferase activity ; GO:0004364 | NOT inferred from key residues biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTD3, CG4381, DmGST22, Gst, gstD22, GstD22, BcDNA:LP11313, GstD3, GSTD3, GST-D3, D3, gstd3, gstD3" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG4381 11-Aug-17 DroID_v2017_08 "Drer\mars, Drer\gstt2, Drer\vars, Drer\gstr, Drer\eef1g, Drer\gstt1b, Drer\gstt1a, Drer\eef1e1" "Scer\YGR201C, Scer\GTT1, Scer\URE2, Scer\CAM1, Scer\GTT2, Scer\TEF4" Cele\gst-34 "Xtro\gstt1, Xtro\eef1e1, Xtro\eef1g" "Mmus\Gstt4, Mmus\Mars, Mmus\Gstt3, Mmus\Eef1g, Mmus\Vars, Mmus\Gstt2, Mmus\Eef1e1, Mmus\Gstt1" "Hsap\GSTT1, Hsap\VARS, Hsap\GSTT2B, Hsap\GSTT2, Hsap\EEF1G, Hsap\EEF1E1, Hsap\MARS" larval stage organism

"viable,body color defective" mesothoracic tergum FBgn0036529 pgant8 polypeptide GalNAc transferase 8 http://flybase.org/reports/FBgn0036529 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 Golgi stack ; GO:0005795 | non-traceable author statement "CG7297, pgant8" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases, IPR027791:Galactosyltransferase, C-terminal" CG7297 11-Aug-17 DroID_v2017_08 "Drer\galnt16, Drer\galnt7, Drer\LOC100535692, Drer\LOC100334784, Drer\galnt12, Drer\galnt2, Drer\galnt13, Drer\galnt18a, Drer\galnt10, Drer\galnt3, Drer\poc1bl, Drer\wbscr17, Drer\galnt8a.1, Drer\galnt18b, Drer\LOC101886587, Drer\galnt8b, Drer\galnt11, Drer\galnt6, Drer\LOC568645, Drer\LOC101882942, Drer\LOC103910015, Drer\si:ch211-15e22.3, Drer\galnt14, Drer\galnt1, Drer\galnt9" - "Cele\gly-3, Cele\gly-11, Cele\gly-10, Cele\gly-9, Cele\gly-8, Cele\gly-7" "Xtro\galnt1, Xtro\wbscr17, Xtro\galnt7, Xtro\galnt14, Xtro\galnt10, Xtro\galnt2, Xtro\galnt12, Xtro\galnt9, Xtro\galnt4, Xtro\galnt16, Xtro\galnt6.1, Xtro\galnt15, Xtro\galnt13" "Mmus\Galnt18, Mmus\Galnt13, Mmus\Galnt14, Mmus\Galnt5, Mmus\Galnt12, Mmus\Wbscr17, Mmus\Galnt15, Mmus\Galnt1, Mmus\Galnt2, Mmus\Galnt10, Mmus\Galnt4, Mmus\Galnt9, Mmus\Galnt7, Mmus\Galntl6, Mmus\Galnt3, Mmus\Galnt11, Mmus\Galnt16, Mmus\Galnt6, Mmus\Galntl5" "Hsap\GALNTL5, Hsap\GALNT12, Hsap\POC1B-GALNT4, Hsap\GALNT4, Hsap\GALNT18, Hsap\GALNT9, Hsap\GALNT5, Hsap\GALNTL6, Hsap\WBSCR17, Hsap\GALNT11, Hsap\GALNT1, Hsap\GALNT7, Hsap\GALNT8, Hsap\GALNT14, Hsap\GALNT13, Hsap\GALNT2, Hsap\GALNT3, Hsap\GALNT6, Hsap\GALNT10, Hsap\GALNT16, Hsap\GALNT15" viable DRSC26909 K -0.326693474 0.222324759 -0.235142638 -0.163614424 2.697086751 0.395103467 FBgn0014348 ms(2)HB123 ms(2)HB123 http://flybase.org/reports/FBgn0014348 - gene - - - ms(2)HB123 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020915 Ost Ostrich http://flybase.org/reports/FBgn0020915 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Ost, ost" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal - all die before end of pupal stage,recessive,some die during pupal stage" wing FBgn0267036 CR45480 - http://flybase.org/reports/FBgn0267036 non_protein_coding_gene - - - CR45480 - CR45480 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045958 anon-AE003774.1 anon-AE003774.1 http://flybase.org/reports/FBgn0045958 gene - - - anon-AE003774.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003375 Sgs5 Salivary gland secretion 5 http://flybase.org/reports/FBgn0003375 FBgn0063132 protein_coding_gene - - - "sgs5, SGS-5, Sgs, Sgs-5, CG7596, BcDNA:LP02306, Sgs5, LP02306" - CG7596 11-Aug-17 DroID_v2017_08 - - Cele\F46F5.16 - - - larval stage | late third instar larval stage embryonic/larval salivary gland

viable FBgn0053668 CG33668 - http://flybase.org/reports/FBgn0053668 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33668 - CG33668 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000475 dn - http://flybase.org/reports/FBgn0000475 - gene - - - dn - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced,heat sensitive,sterile,eye color defective" "pigment cell,testis,spermathecum,genitalia" FBgn0016844 l(1)N19 lethal (1) N19 http://flybase.org/reports/FBgn0016844 - gene - - - "l(1)N19, N19" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028593 l(2)s9998 lethal (2) s9998 http://flybase.org/reports/FBgn0028593 gene - - - l(2)s9998 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000640 Fbp2 Fat body protein 2 http://flybase.org/reports/FBgn0000640 - protein_coding_gene "alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from electronic annotation with InterPro:IPR002424, InterPro:IPR002426 nutrient reservoir activity ; GO:0045735 | non-traceable author statement" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002424 lipid particle ; GO:0005811 | inferred from direct assay "CG3763, T19, P6, Fbp2, Fbp-2" "IPR002424:Alcohol dehydrogenase, insect-type, IPR002426:Alcohol dehydrogenase, Ceratitis-type, IPR016040:NAD(P)-binding domain, IPR002347:Short-chain dehydrogenase/reductase SDR" CG3763 11-Aug-17 DroID_v2017_08 "Drer\zgc:56585, Drer\hpgd, Drer\cbr4" Scer\SPS19 "Cele\W03F9.9, Cele\T01G6.10, Cele\C01G12.5, Cele\C06B8.3, Cele\T01G6.1" Xtro\hpgd "Mmus\Cbr4, Mmus\Hpgd" "Hsap\CBR4, Hsap\HPGD" " prepupal stage , larval stage | third instar " "viable,visible" trichogen cell FBgn0025783 anon-MMS35 anon-MMS35 http://flybase.org/reports/FBgn0025783 - gene - - - anon-MMS35 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060353 l(3)S141908 lethal (3) S141908 http://flybase.org/reports/FBgn0060353 gene - - - "1419/08, l(3)S141908" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0038945 CG5386 - http://flybase.org/reports/FBgn0038945 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5386 IPR015943:WD40/YVTN repeat-like-containing domain CG5386 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033834 CG4744 - http://flybase.org/reports/FBgn0033834 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4744 - CG4744 11-Aug-17 DroID_v2017_08 - - - - - - viable heart primordium DRSC28696 K 0.592616026 0.21847114 0.449421079 0.138939399 0.12822044 1.929923116 FBgn0033736 CG13154 - http://flybase.org/reports/FBgn0033736 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13154 - CG13154 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034978 CG3257 - http://flybase.org/reports/FBgn0034978 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey117, CG3257" IPR032061:Domain of unknown function DUF4802 CG3257 11-Aug-17 DroID_v2017_08 - - - - - - "visible,planar polarity defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0016929 smi28E smell impaired 28E http://flybase.org/reports/FBgn0016929 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi28E - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0051677 CG31677 - http://flybase.org/reports/FBgn0051677 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31677 - CG31677 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036977 CG5665 - http://flybase.org/reports/FBgn0036977 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG5665, cg5665" "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG5665 11-Aug-17 DroID_v2017_08 "Drer\lipg, Drer\lipia, Drer\pla1a, Drer\LOC100331214, Drer\LOC101884800, Drer\lipca, Drer\lipib, Drer\lpl" - - "Xtro\lpl, Xtro\lipg" "Mmus\Pnliprp1, Mmus\Pnlip, Mmus\Lipg, Mmus\Liph, Mmus\Lipc, Mmus\Lpl, Mmus\Pla1a, Mmus\Pnliprp2, Mmus\Lipi" "Hsap\PNLIPRP2, Hsap\LPL, Hsap\PNLIPRP1, Hsap\LIPC, Hsap\PNLIP, Hsap\PNLIPRP3, Hsap\LIPI, Hsap\LIPH, Hsap\PLA1A, Hsap\LIPG" DRSC11783 IE 1.944524509 -0.45976208 2.518269033 -0.054907318 -0.223123894 1.469520795 FBgn0029987 CG15330 - http://flybase.org/reports/FBgn0029987 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG15330 - CG15330 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0085676 CG41537 - http://flybase.org/reports/FBgn0085676 protein_coding_gene - - - CG41537 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266173 pre-mod(mdg4)-K - http://flybase.org/reports/FBgn0266173 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-K, CG44879" "IPR007588:Zinc finger, FLYWCH-type" CG44879 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Flywch1, Mmus\Flywch2" - FBgn0038665 euc eucalyptus http://flybase.org/reports/FBgn0038665 protein_coding_gene - detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000009767 "CG12269, euc" IPR003033:SCP2 sterol-binding domain CG12269 11-Aug-17 DroID_v2017_08 "Drer\scp2a, Drer\stoml1, Drer\hsdl2" - Cele\nlt-1 "Xtro\scp2, Xtro\stoml1, Xtro\hsdl2" "Mmus\Scp2d1, Mmus\Stoml1, Mmus\Hsdl2, Mmus\Scp2" "Hsap\SCP2D1, Hsap\STOML1, Hsap\SCP2, Hsap\HSDL2" viable FBgn0083987 snRNA:U11 small nuclear RNA U11 http://flybase.org/reports/FBgn0083987 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0005689" U12-type spliceosomal complex ; GO:0005689 | inferred from physical interaction with snRNA:U12:73B "CR34151, dU11 snRNA, Dm-149, snmRNA:149, CR33708, snRNA:U11, U11, 63E-F U11" - CR34151 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011110 l(1)Q71b lethal (1) Q71b http://flybase.org/reports/FBgn0011110 FBgn0010210 gene - - - l(1)Q71b - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029629 eIF3g1 eukaryotic translation initiation factor 3 subunit g1 http://flybase.org/reports/FBgn0029629 protein_coding_gene translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000039396 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | inferred from sequence or structural similarity regulation of cell cycle ; GO:0051726 | inferred from direct assay translational initiation ; GO:0006413 | inferred from sequence or structural similarity mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000039396 "CG8636, eIF3-S4, cg8636, eIF-3, eIF s4, eIF3g, eIF3g1, eIF3ga" "IPR000504:RNA recognition motif domain, IPR017334:Eukaryotic translation initiation factor 3 subunit G, IPR024675:Eukaryotic translation initiation factor 3 subunit G, N-terminal, IPR034240:eIF3G, RNA recognition motif" CG8636 11-Aug-17 DroID_v2017_08 Drer\eif3g Scer\TIF35 Cele\eif-3.G Xtro\eif3g Mmus\Eif3g Hsap\EIF3G lethal DRSC18427 IE 1.803190799 -1.112372353 -6.283402272 -5.485621521 0.231490839 0.647321104 FBgn0260477 CG30283 - http://flybase.org/reports/FBgn0260477 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SP37, SPH37, CG10450, CG30283" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG30283 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.5, Drer\gzm3, Drer\si:dkey-21e2.12, Drer\si:dkey-21e2.7, Drer\si:dkey-21e2.15, Drer\si:ch211-165b19.9, Drer\LOC558805" - Cele\try-3 - "Mmus\Gzmc, Mmus\Gzmb, Mmus\Klk1b9, Mmus\Ctsg, Mmus\Gzmg, Mmus\Mcpt8, Mmus\Cma2, Mmus\Mcpt9, Mmus\Mcpt4, Mmus\Gzmd, Mmus\Klk6, Mmus\Gzme, Mmus\Gzmf, Mmus\Klk1b5, Mmus\Mcpt1, Mmus\Egfbp2, Mmus\Cma1" "Hsap\GZMH, Hsap\GZMB, Hsap\CMA1, Hsap\CTSG" viable FBgn0015586 Acp76A Accessory gland protein 76A http://flybase.org/reports/FBgn0015586 - protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG3801, Acp76, Acp76A, Spn76A" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG3801 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-186e20.7, Drer\zgc:174260, Drer\serpina7, Drer\serpina1l, Drer\zgc:174259, Drer\serpina1, Drer\serpinf2a, Drer\serpine1" - "Cele\srp-7, Cele\srp-3, Cele\srp-1, Cele\srp-6" Xtro\serpinf2 "Mmus\Serpina3f, Mmus\Serpina1a, Mmus\Serpina1b, Mmus\Serpina3j, Mmus\Serpina5, Mmus\Serpina3m, Mmus\Serpina3b, Mmus\Serpina3n, Mmus\Serpina3k, Mmus\Serpina6, Mmus\Serpinf2, Mmus\Serpina1d, Mmus\Serpina12, Mmus\Serpina3i, Mmus\Serpina11, Mmus\Serpina3c, Mmus\Serpina1e, Mmus\Serpina16, Mmus\Serpina9, Mmus\Serpina1c, Mmus\Serpina1f, Mmus\Serpina3a, Mmus\Serpina7, Mmus\Serpina3g" "Hsap\SERPINA12, Hsap\SERPINA4, Hsap\SERPINA6, Hsap\SERPINA7, Hsap\SERPINA9, Hsap\SERPINA3, Hsap\SERPINA11, Hsap\SERPINA1, Hsap\SERPINB12, Hsap\SERPINA2, Hsap\SERPINF2, Hsap\SERPINA5" adult stage | male " male accessory gland

, male accessory gland main cell

" viable FBgn0264426 CG43844 - http://flybase.org/reports/FBgn0264426 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43844, CG43844" - CG43844 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038133 Osi22 Osiris 22 http://flybase.org/reports/FBgn0038133 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG8644, Osi22" - CG8644 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266786 CR45251 - http://flybase.org/reports/FBgn0266786 non_protein_coding_gene - - - CR45251 - CR45251 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034994 Ir60a Ionotropic receptor 60a http://flybase.org/reports/FBgn0034994 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir60a, IR60a, DmelIR60a, CG13576" - CG13576 11-Aug-17 DroID_v2017_08 "Drer\grid1a, Drer\LOC100537813, Drer\grid1b" - Cele\glr-8 - "Mmus\Grik4, Mmus\Grid1" Hsap\GRID1 "partially lethal - majority die,some die during pupal stage" FBgn0034545 CG13438 - http://flybase.org/reports/FBgn0034545 protein_coding_gene - - - CG13438 - CG13438 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027082 ProRS-m "Prolyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0027082 FBgn0035361 protein_coding_gene "proline-tRNA ligase activity ; GO:0004827 | inferred from electronic annotation with InterPro:IPR002316, InterPro:IPR004500 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002314, InterPro:IPR002315, InterPro:IPR002316, InterPro:IPR004500 glycine-tRNA ligase activity ; GO:0004820 | inferred from electronic annotation with InterPro:IPR002315 proline-tRNA ligase activity ; GO:0004827 | traceable author statement" "prolyl-tRNA aminoacylation ; GO:0006433 | inferred from electronic annotation with InterPro:IPR002316, InterPro:IPR004500 glycyl-tRNA aminoacylation ; GO:0006426 | inferred from electronic annotation with InterPro:IPR002315 prolyl-tRNA aminoacylation ; GO:0006433 | traceable author statement" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002315, InterPro:IPR002316, InterPro:IPR004500 mitochondrion ; GO:0005739 | traceable author statement" "ProRS, PRS, CG12186, ProRS-m, Aats-pro" "IPR002314:Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR002316:Proline-tRNA ligase, class IIa, IPR004154:Anticodon-binding, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR002315:Glycyl-tRNA synthetase, IPR033730:Prokaryote proline-tRNA ligase core domain" CG12186 11-Aug-17 DroID_v2017_08 "Drer\atpv0e2, Drer\pars2" Scer\AIM10 "Cele\vha-17, Cele\pars-2" "Xtro\atp6v0e2, Xtro\pars2, Xtro\atp6v0e1" "Mmus\Pars2, Mmus\Atp6v0e2" Hsap\PARS2 embryonic stage

ubiquitous "viable,decreased cell size,cell autonomous,somatic clone" lysosome & larval fat body | somatic clone | cell autonomous FBgn0001331 K230 K230 http://flybase.org/reports/FBgn0001331 - gene - - - K230 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020385 pug pugilist http://flybase.org/reports/FBgn0020385 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000559, InterPro:IPR020628 methenyltetrahydrofolate cyclohydrolase activity ; GO:0004477 | non-traceable author statement formate-tetrahydrofolate ligase activity ; GO:0004329 | inferred from biological aspect of ancestor with PANTHER:PTN001598237 methylenetetrahydrofolate dehydrogenase (NADP+) activity ; GO:0004488 | non-traceable author statement methenyltetrahydrofolate cyclohydrolase activity ; GO:0004477 | inferred from biological aspect of ancestor with PANTHER:PTN001598237 formate-tetrahydrofolate ligase activity ; GO:0004329 | non-traceable author statement methylenetetrahydrofolate dehydrogenase (NADP+) activity ; GO:0004488 | inferred from biological aspect of ancestor with PANTHER:PTN001598237" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000672, InterPro:IPR020630, InterPro:IPR020631, InterPro:IPR020867 purine nucleobase biosynthetic process ; GO:0009113 | inferred from biological aspect of ancestor with PANTHER:PTN001598237 cellular amino acid biosynthetic process ; GO:0008652 | non-traceable author statement 10-formyltetrahydrofolate biosynthetic process ; GO:0009257 | inferred from biological aspect of ancestor with PANTHER:PTN001598237" lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG4067, bs14h02.y1, pugD, MTHFD, Pug, pug" "IPR000559:Formate-tetrahydrofolate ligase, FTHFS, IPR000672:Tetrahydrofolate dehydrogenase/cyclohydrolase, IPR016040:NAD(P)-binding domain, IPR020628:Formate-tetrahydrofolate ligase, FTHFS, conserved site, IPR020630:Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, IPR020631:Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020867:Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site" CG4067 11-Aug-17 DroID_v2017_08 "Drer\mthfd1a, Drer\mthfd2, Drer\mthfd1l, Drer\mthfd1b" "Scer\ADE3, Scer\MIS1, Scer\MTD1" "Cele\K07E3.4, Cele\dao-3" "Xtro\mthfd1l, Xtro\mthfd1" "Mmus\Mthfd2, Mmus\Mthfd1l, Mmus\Mthfd2l, Mmus\Mthfd1" "Hsap\MTHFD2L, Hsap\MTHFD2, Hsap\MTHFD1, Hsap\MTHFD1L" "wild-type,visible,recessive,viable,eye color defective,dominant" "eye,pigment cell" FBgn0067303 DDB2 DDB2 http://flybase.org/reports/FBgn0067303 gene - - - DDB2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034430 mip40 Myb-interacting protein 40 http://flybase.org/reports/FBgn0034430 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR028226 eggshell chorion gene amplification ; GO:0007307 | inferred by curator from GO:0031523 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype transcriptional repressor complex ; GO:0017053 | inferred from electronic annotation with InterPro:IPR028226 Myb complex ; GO:0031523 | inferred from direct assay "Mip40, CG15119, p40, mip40" IPR028226:Protein LIN37 CG15119 11-Aug-17 DroID_v2017_08 "Drer\smim4, Drer\si:ch211-68a17.7, Drer\lin37" - Cele\lin-37 Xtro\lin37 "Mmus\Lin37, Mmus\Smim4" "Hsap\SMIM4, Hsap\LIN37, Hsap\C12orf73" "viable,female sterile,recessive,male sterile,meiotic cell cycle defective,male" testis DRSC06541 IE 2.546585413 -0.064869528 2.922653321 -1.284611315 1.335397368 -0.139723932 FBgn0262582 cic capicua http://flybase.org/reports/FBgn0262582 protein_coding_gene repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with gro sequence-specific DNA binding ; GO:0043565 | inferred from direct assay "negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype eye morphogenesis ; GO:0048592 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap terminal region determination ; GO:0007362 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Cic, cic, fet, CG5067, E(Dl)D49, CG5060, CG43122, cics, CIC" "IPR009071:High mobility group box domain, IPR032147:Domain of unknown function DUF4819" CG43122 11-Aug-17 DroID_v2017_08 "Drer\cicb, Drer\cica" - Cele\nhr-27 - Mmus\Cic Hsap\CIC embryonic stage | early embryonic stage | early organism | 10-90% egg length

FBgn0013489 l(1)6PP7 lethal (1) 6PP7 http://flybase.org/reports/FBgn0013489 - gene - - - l(1)6PP7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0024839 rk(2)364 rk(2)364 http://flybase.org/reports/FBgn0024839 - gene - - - rk(2)364 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011023 l(3)s2253 lethal (3) s2253 http://flybase.org/reports/FBgn0011023 - gene - - - l(3)s2253 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069157 mcl(3)Z2566 mcl(3)Z2566 http://flybase.org/reports/FBgn0069157 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z2566 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0001089 Gal beta galactosidase http://flybase.org/reports/FBgn0001089 FBgn0031761 protein_coding_gene beta-galactosidase activity ; GO:0004565 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Gal galactose metabolic process ; GO:0006012 | inferred from direct assay vacuole ; GO:0005773 | inferred from biological aspect of ancestor with PANTHER:PTN000602923 "lacZ-1, gal, beta-GAL, beta-Gal-1, CG9092, Gal, beta-gal, dbeta-Gal" "IPR001944:Glycoside hydrolase, family 35, IPR017853:Glycoside hydrolase superfamily, IPR008979:Galactose-binding domain-like, IPR026283:Beta-galactosidase 1-like, IPR031330:Glycoside hydrolase 35, catalytic domain, IPR025300:Beta-galactosidase jelly roll domain" CG9092 11-Aug-17 DroID_v2017_08 "Drer\slc37a4b, Drer\glb1, Drer\LOC100332851, Drer\glb1l, Drer\si:dkey-224e22.2" - "Cele\bgal-2, Cele\bgal-1" "Xtro\glb1l, Xtro\glb1" "Mmus\Glb1l3, Mmus\Gm1110, Mmus\Glb1l2, Mmus\Glb1l, Mmus\Glb1" "Hsap\GLB1, Hsap\GLB1L3, Hsap\GLB1L, Hsap\GLB1L2, Hsap\TMPPE" " adult stage , pupal stage " " pupal stage , adult stage " FBgn0034493 CG8908 - http://flybase.org/reports/FBgn0034493 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 CG8908 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR026082:ABC transporter A, ABCA" CG8908 11-Aug-17 DroID_v2017_08 "Drer\abca1b, Drer\abca3b, Drer\abca2, Drer\abca12, Drer\abch1, Drer\abca1a, Drer\abca5" Scer\CAF16 "Cele\abt-4, Cele\abt-2, Cele\abt-5, Cele\ced-7, Cele\abt-1" "Xtro\abca2, Xtro\abca1, Xtro\abca8, Xtro\abca4, Xtro\abca3, Xtro\abca9, Xtro\abca10" "Mmus\Abca7, Mmus\Abca4, Mmus\Abca8a, Mmus\Abca1, Mmus\Abca6, Mmus\Abca13, Mmus\Abca14, Mmus\Abca16, Mmus\Abca2, Mmus\Abca17, Mmus\Abca5, Mmus\Abca15, Mmus\Abca9, Mmus\Abca12, Mmus\Abca3, Mmus\Abca8b" "Hsap\ABCA5, Hsap\ABCA12, Hsap\ABCA13, Hsap\ABCA4, Hsap\ABCA10, Hsap\ABCA8, Hsap\ABCA9, Hsap\ABCA6, Hsap\ABCA2, Hsap\ABCA7, Hsap\ABCA1, Hsap\ABCA3" "viable,fertile" FBgn0259098 CG42246 - http://flybase.org/reports/FBgn0259098 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42246, Dm_X:38130" - CG42246 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266275 CR44960 - http://flybase.org/reports/FBgn0266275 non_protein_coding_gene - - - CR44960 - CR44960 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260439 Pp2A-29B Protein phosphatase 2A at 29B http://flybase.org/reports/FBgn0260439 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype centrosome cycle ; GO:0007098 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype protein phosphatase type 2A complex ; GO:0000159 | inferred from sequence or structural similarity centriole ; GO:0005814 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG13383, CG17291, PP2A-A, PP2A-29B, Pp2A-29B, Pp2A, PP2A, A/PR65, DPR65, PR65, CG33297, PP2A A, dPP2A A, Pp2A29B, PP2A[A], PP2A 29B, 29B, pp2A-29B" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR021133:HEAT, type 2" CG17291 11-Aug-17 DroID_v2017_08 "Drer\ppp2r1b, Drer\cops8, Drer\ppp2r1a" Scer\TPD3 Cele\paa-1 "Xtro\pdgfb, Xtro\cops8, Xtro\ppp2r1a" "Mmus\Cops8, Mmus\Ppp2r1b, Mmus\Ppp2r1a" "Hsap\COPS8, Hsap\PPP2R1B, Hsap\PPP2R1A" " larval stage | third instar , embryonic stage , adult stage && oogenesis stage , embryonic stage&&larval stage&&adult stage , embryonic stage | early , embryonic stage | late , embryonic stage | stage 9-11 , adult stage " " imaginal disc

,

ubiquitous , oocyte

, larval brain

, gonad

, neuroblast

, supraesophageal ganglion

, nurse cell

, embryonic/larval salivary gland

, adult brain

, ventral nerve cord

, adult midgut

" "lethal,recessive,neuroanatomy defective,viable,visible" "neuroblast,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,supernumerary,mesothoracic tergum,synapse,neuromuscular junction,wing margin" FBgn0265995 CR44770 - http://flybase.org/reports/FBgn0265995 non_protein_coding_gene - - - "CR44770, lincRNA.145" - CR44770 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036869 CG14094 - http://flybase.org/reports/FBgn0036869 protein_coding_gene - - - CG14094 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263078 CG43339 - http://flybase.org/reports/FBgn0263078 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43339, CG42627, CG31791" - CG43339 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038948 PSR phosphatidylserine receptor http://flybase.org/reports/FBgn0038948 protein_coding_gene peptidyl-lysine 5-dioxygenase activity ; GO:0070815 | inferred from sequence or structural similarity with UniProtKB:Q6NYC1 negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype inferred from genetic interaction with hid peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine ; GO:0018395 | inferred from sequence or structural similarity with UniProtKB:Q6NYC1 negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with puc cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q6NYC1 nucleus ; GO:0005634 | inferred from direct assay "dPSR, CG5383, PS, L0022859, BEST:LD22859, PSR, psr, Psr" IPR003347:JmjC domain CG5383 11-Aug-17 DroID_v2017_08 Drer\jmjd6 - Cele\psr-1 Xtro\jmjd6 Mmus\Jmjd6 Hsap\JMJD6 "viable,fertile,visible,male" "ommatidium,male genitalia,wing,eye disc,trichogen cell" FBgn0060512 l(3)S104104 lethal (3) S104104 http://flybase.org/reports/FBgn0060512 gene - - - "1041/04, l(3)S104104" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0002513 l(3)Sp5 lethal (3) Sp5 http://flybase.org/reports/FBgn0002513 - gene - - - l(3)Sp5 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038612 cona corona http://flybase.org/reports/FBgn0038612 protein_coding_gene - synaptonemal complex assembly ; GO:0007130 | inferred from mutant phenotype synapsis ; GO:0007129 | inferred from mutant phenotype synaptonemal complex ; GO:0000795 | inferred from direct assay "CG7676, cona" - CG7676 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267745 CR46076 - http://flybase.org/reports/FBgn0267745 non_protein_coding_gene - - - "CR46076, lincRNA.875" - CR46076 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261704 CG42740 - http://flybase.org/reports/FBgn0261704 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42740 - CG42740 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034499 Cpr56F Cuticular protein 56F http://flybase.org/reports/FBgn0034499 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr56F, CG9036, DmelCpr56F" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG9036 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0265925 CR44714 - http://flybase.org/reports/FBgn0265925 non_protein_coding_gene - - - CR44714 - CR44714 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001140 grotle grotle http://flybase.org/reports/FBgn0001140 - gene - - - "gr, grotle, grt" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "wing,posterior cell" FBgn0275432 CR46264 - http://flybase.org/reports/FBgn0275432 non_protein_coding_gene - - - CR46264 - CR46264 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011042 l(1)Stark-a lethal (1) of Stark a http://flybase.org/reports/FBgn0011042 FBgn0010212 gene - - - "l(1)Stark-a, l(1)Sa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010891 l(3)06487 lethal (3) 06487 http://flybase.org/reports/FBgn0010891 - gene - - - "6487, l(3)06487" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260281 GSd455 - http://flybase.org/reports/FBgn0260281 gene - - - GSd455 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034477 CG13872 - http://flybase.org/reports/FBgn0034477 protein_coding_gene - - - CG13872 - CG13872 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265038 CR44155 - http://flybase.org/reports/FBgn0265038 non_protein_coding_gene - - - CR44155 - CR44155 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031419 CG15390 - http://flybase.org/reports/FBgn0031419 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from electronic annotation with InterPro:IPR003690 rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000317011 single-stranded RNA binding ; GO:0003727 | inferred from biological aspect of ancestor with PANTHER:PTN000317011 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003690 developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN000317011 RNA splicing ; GO:0008380 | inferred from biological aspect of ancestor with PANTHER:PTN000317011 ribosome assembly ; GO:0042255 | inferred from biological aspect of ancestor with PANTHER:PTN000317011" - "BcDNA:RE18748, CG15390" "IPR003690:Transcription termination factor, mitochondrial/chloroplastic" CG15390 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-94h10.5 - Cele\K11D2.5 - Mmus\Mterf4 Hsap\MTERF4 viable FBgn0030570 CG12540 - http://flybase.org/reports/FBgn0030570 protein_coding_gene - - - "BcDNA:RE49992, CG12540" - CG12540 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266073 CR44826 - http://flybase.org/reports/FBgn0266073 non_protein_coding_gene - - - CR44826 - CR44826 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259179 CG42284 - http://flybase.org/reports/FBgn0259179 protein_coding_gene - - - "CG42284, CG13529, CG30264, CG13528, CG30266" "IPR002110:Ankyrin repeat, IPR007858:Dpy-30 motif, IPR020683:Ankyrin repeat-containing domain" CG42284 11-Aug-17 DroID_v2017_08 "Drer\ankef1b, Drer\ank2a, Drer\si:dkey-86e18.2, Drer\tnksb, Drer\si:ch73-193i2.2, Drer\ankef1a, Drer\pidd1, Drer\tnksa, Drer\ankdd1a, Drer\si:ch211-203b8.6, Drer\ank3b, Drer\ank3a, Drer\ank1b, Drer\trpn1, Drer\hace1, Drer\ankdd1b" - "Cele\F34D10.6, Cele\mlt-2" "Xtro\ank2, Xtro\ank3, Xtro\cat2, Xtro\ank1, Xtro\LOC100492885, Xtro\ankdd1a, Xtro\asb7, Xtro\ankef1, Xtro\hace1, Xtro\tnks2" "Mmus\Rnasel, Mmus\Ankrd60, Mmus\Ank1, Mmus\Ankrd65, Mmus\Tnks, Mmus\Ankdd1a, Mmus\4931423N10Rik, Mmus\Ankrd61, Mmus\Ankrd42, Mmus\Hace1, Mmus\Pidd1, Mmus\Ank2, Mmus\Ankdd1b, Mmus\Ank3, Mmus\Asb7, Mmus\Ankef1, Mmus\Ankrd7, Mmus\Tnks2, Mmus\Ankrd53, Mmus\Ankrd44" "Hsap\RNASEL, Hsap\ANK2, Hsap\ANKRD65, Hsap\TNKS, Hsap\ASB7, Hsap\TNKS2, Hsap\PIDD1, Hsap\HACE1, Hsap\ANK1, Hsap\ANKEF1, Hsap\ANKDD1B, Hsap\ANK3, Hsap\ANKRD61, Hsap\ANKRD60, Hsap\ANKDD1A, Hsap\ANKRD53" FBgn0039207 CG5789 - http://flybase.org/reports/FBgn0039207 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011527 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 "Dme_CG5789, CG5789" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG5789 11-Aug-17 DroID_v2017_08 "Drer\abcc10, Drer\abcc2, Drer\abcc13, Drer\LOC100329706, Drer\abcc12, Drer\abcc4, Drer\abcc6b.2, Drer\abcc8, Drer\abcc5, Drer\abcc9, Drer\abcc1, Drer\abcc6a, Drer\cftr, Drer\abcc3" "Scer\YKR104W, Scer\YOR1, Scer\NFT1, Scer\BPT1, Scer\YCF1, Scer\VMR1, Scer\YBT1" "Cele\mrp-6, Cele\mrp-2, Cele\mrp-3, Cele\mrp-8, Cele\mrp-4, Cele\mrp-1, Cele\mrp-5, Cele\mrp-7" "Xtro\abcc6, Xtro\cftr, Xtro\abcc10, Xtro\abcc1, Xtro\abcc4, Xtro\abcc3" "Mmus\Abcc10, Mmus\Abcc2, Mmus\Abcc9, Mmus\Cftr, Mmus\Abcc12, Mmus\Abcc4, Mmus\Abcc1, Mmus\Abcc3, Mmus\Abcc8, Mmus\Abcc6, Mmus\Abcc5" "Hsap\ABCC4, Hsap\ABCC2, Hsap\ABCC1, Hsap\ABCC10, Hsap\ABCC8, Hsap\ABCC12, Hsap\CFTR, Hsap\LOC105369239, Hsap\ABCC11, Hsap\ABCC9, Hsap\ABCC5, Hsap\ABCC6, Hsap\ABCC3" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0013383 acj7 abnormal-chemosensory-jump-7 http://flybase.org/reports/FBgn0013383 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,recessive" FBgn0259939 ttd1 TRPL translocation defect 1 http://flybase.org/reports/FBgn0259939 protein_coding_gene - - - ttd1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003914 U Upturned http://flybase.org/reports/FBgn0003914 - gene - - - U - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive,viable,eye color defective,body color defective" "wing,posterior scutellar bristle,cuticle" FBgn0000041 act actidione-sensitive http://flybase.org/reports/FBgn0000041 - gene - - - act - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0001903 l(2)22Ad lethal (2) 22Ad http://flybase.org/reports/FBgn0001903 - gene - - - "l(2)neh-17, l(2)neh17, l(2)22Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263961 BG01700 - http://flybase.org/reports/FBgn0263961 gene - - - BG01700 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,starvation stress response defective,male limited,temperature response defective,gravitaxis defective" FBgn0031217 CG11377 - http://flybase.org/reports/FBgn0031217 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR018097 - - "CT31762, CG11377" "IPR000742:EGF-like domain, IPR002049:Laminin EGF domain, IPR006212:Furin-like repeat, IPR009030:Growth factor receptor cysteine-rich domain, IPR013032:EGF-like, conserved site, IPR018097:EGF-like calcium-binding, conserved site, IPR021852:Domain of unknown function DUF3456, IPR001881:EGF-like calcium-binding domain" CG11377 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-226h7.5, Drer\LOC100005636, Drer\creld2, Drer\si:ch73-181m17.1, Drer\thbd, Drer\LOC569741, Drer\si:dkey-239b22.2, Drer\LOC568930, Drer\oit3, Drer\zmp:0000001031, Drer\zgc:153932" - "Cele\mec-9, Cele\dyf-7, Cele\spe-9, Cele\F09E8.2" "Xtro\creld2, Xtro\creld1" "Mmus\Creld2, Mmus\Creld1, Mmus\Oit3" "Hsap\CRELD2, Hsap\CRELD1, Hsap\OIT3" FBgn0043048 anon-60Ae anon-60Ae http://flybase.org/reports/FBgn0043048 gene - - - anon-60Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044111 E(rst)C329 E(rst)C329 http://flybase.org/reports/FBgn0044111 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C329, E(rst)C329" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001299 kdu kudu http://flybase.org/reports/FBgn0001299 - gene - - - kdu - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile egg FBgn0262379 mir-1012 mir-1012 stem loop http://flybase.org/reports/FBgn0262379 miRNA_gene - - - "mir-1012, miR-1012, dme-mir-1012, CR42902, dme-miR-1012" - CR42902 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing margin,1st posterior cell" FBgn0024289 Sodh-1 Sorbitol dehydrogenase 1 http://flybase.org/reports/FBgn0024289 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR002328 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR002328" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR002328, InterPro:IPR013149, InterPro:IPR013154 sleep ; GO:0030431 | inferred from expression pattern" - "Sodh, DM_7298873, Sdh-1, CG1982, BG:DS00464.2, Sodh-1" "IPR002328:Alcohol dehydrogenase, zinc-type, conserved site, IPR011032:GroES-like, IPR013149:Alcohol dehydrogenase, C-terminal, IPR013154:Alcohol dehydrogenase, N-terminal, IPR016040:NAD(P)-binding domain, IPR020843:Polyketide synthase, enoylreductase domain" CG1982 11-Aug-17 DroID_v2017_08 "Drer\c2h1orf27, Drer\sord" "Scer\SOR2, Scer\XYL2, Scer\BDH2, Scer\SOR1, Scer\BDH1" "Cele\R04B5.5, Cele\R04B5.6, Cele\D2063.1" Xtro\sord Mmus\Sord Hsap\SORD " larval stage , pupal stage , adult stage " viable FBgn0054044 CR34044 - http://flybase.org/reports/FBgn0054044 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1053, CG34044, CR34044" - CR34044 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029016 l(3)77CDi lethal (3) 77CDi http://flybase.org/reports/FBgn0029016 gene - - - l(3)77CDi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0036648 CG4098 - http://flybase.org/reports/FBgn0036648 protein_coding_gene adenosine-diphosphatase activity ; GO:0043262 | inferred from biological aspect of ancestor with PANTHER:PTN000989736 - - "CG4098, CG4098-PA" "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like" CG4098 11-Aug-17 DroID_v2017_08 Drer\nudt9 - Cele\ndx-6 Xtro\LOC100491139 "Mmus\Nudt9, Mmus\Trpm2" "Hsap\NUDT9, Hsap\TRPM2" viable FBgn0259932 CG42455 - http://flybase.org/reports/FBgn0259932 protein_coding_gene - - - "CG42455, Dromel_CG11989_FBtr0076348_ard1_uORF" IPR031851:Protein of unknown function DUF4750 CG42455 11-Aug-17 DroID_v2017_08 Drer\si:dkey-206d17.5 - - - Mmus\Smim13 Hsap\SMIM13 FBgn0004381 Klp68D Kinesin-like protein at 68D http://flybase.org/reports/FBgn0004381 - protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity motor activity ; GO:0003774 | inferred from sequence or structural similarity with MGI:MGI:107689 inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from mutant phenotype anterograde axonal transport ; GO:0008089 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity anterograde axonal transport ; GO:0008089 | inferred from expression pattern microtubule associated complex ; GO:0005875 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 "CG7293, DmKlp68D, klp68d, KLP68D, KLP[[64D/68D]], KLP5, KLP-5, Klp5, Klp68D, KLP68Ddm, KIF 3B, KIF3B" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7293 11-Aug-17 DroID_v2017_08 "Drer\LOC100331925, Drer\kif3b, Drer\kif5bb, Drer\kif17, Drer\kifc1, Drer\kif5ba, Drer\kif5ab, Drer\kif3a, Drer\kif3cb, Drer\kif5c" "Scer\KIP1, Scer\KAR3, Scer\CIN8, Scer\SMY1" "Cele\klp-11, Cele\osm-3, Cele\klp-3, Cele\klp-20" "Xtro\kif3c, Xtro\kif5c, Xtro\kif5b, Xtro\kif5a, Xtro\kif3a, Xtro\kif3b, Xtro\kifc1" "Mmus\Kif3a, Mmus\Kifc5b, Mmus\Kif5c, Mmus\Kif17, Mmus\Kif5b, Mmus\Kif5a, Mmus\Kif3c, Mmus\Kif3b, Mmus\Gm1305" "Hsap\KIF3C, Hsap\KIF5A, Hsap\KIF5B, Hsap\KIF3B, Hsap\KIF5C, Hsap\KIFC1, Hsap\KIF3A" " embryonic stage -- adult stage , adult stage , adult stage | male , adult stage | female " " head

, testis

, ovary

" "viable,fertile,neurophysiology defective,auditory perception defective,neuroanatomy defective,lethal,partially lethal - majority die,visible,recessive" "sensillum basiconicum of antennal segment 3,sensillum trichodeum of antennal segment 3,cilium,trichogen cell,mesothoracic tergum" FBgn0069351 Sryip Sryip http://flybase.org/reports/FBgn0069351 gene - - - Sryip - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261108 Atg13 Autophagy-related 13 http://flybase.org/reports/FBgn0261108 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from biological aspect of ancestor with PANTHER:PTN001002756 protein binding ; GO:0005515 | inferred from physical interaction with Atg101 protein kinase regulator activity ; GO:0019887 | inferred from sequence or structural similarity with SGD:S000006389 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype positive regulation of nurse cell apoptotic process ; GO:0045850 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN001002756 autophagy ; GO:0006914 | inferred from mutant phenotype activation of protein kinase activity ; GO:0032147 | inferred from sequence or structural similarity with SGD:S000006389 ATG1/ULK1 kinase complex ; GO:1990316 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001002756 pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN001002756 "Atg13, BcDNA:HL01508, CG7331, atg13, ATG13, dAtg13" IPR018731:Autophagy-related protein 13 CG7331 11-Aug-17 DroID_v2017_08 Drer\atg13 Scer\ATG13 Cele\atg-13 Xtro\atg13 Mmus\Atg13 Hsap\ATG13 FBgn0065603 l(2)SH0862 lethal (2) SH0862 http://flybase.org/reports/FBgn0065603 gene - - - "l(2)SH0862, l(2)SH2 0862" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002713 mei-S8 meiotic from via Salaria 8 http://flybase.org/reports/FBgn0002713 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "meiS8, mei-S8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive" spermatocyte & nuclear chromosome FBgn0002009 l(2)36Fb lethal (2) 36Fb http://flybase.org/reports/FBgn0002009 - gene - - - "l(2)E70, l(2)36Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035321 CG1275 - http://flybase.org/reports/FBgn0035321 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000010357 oxidation-reduction process ; GO:0055114 | inferred from biological aspect of ancestor with PANTHER:PTN000010357 - "anon-WO0118547.260, CG1275, Cyt-b561-1" IPR006593:Cytochrome b561/ferric reductase transmembrane CG1275 11-Aug-17 DroID_v2017_08 "Drer\cyb561, Drer\cybrd1, Drer\cyb561a3b, Drer\cyb561a3a, Drer\dcaf17" - "Cele\F55H2.5, Cele\F39G3.5, Cele\F39G3.4" "Xtro\cyb561, Xtro\cybrd1" "Mmus\Cyb561a3, Mmus\Cyb561, Mmus\Cybrd1" "Hsap\CYB561A3, Hsap\CYB561, Hsap\CYBRD1" "viable,fertile,body color defective" mesothoracic tergum DRSC08294 E 0.537476278 -0.346894408 -2.182554256 -0.211176242 0.950471043 0.033645959 FBgn0041630 Hexo1 Hexosaminidase 1 http://flybase.org/reports/FBgn0041630 protein_coding_gene beta-N-acetylglucosaminidase activity ; GO:0016231 | inferred from direct assay N-glycan processing ; GO:0006491 | inferred from mutant phenotype protein deglycosylation ; GO:0006517 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "HEX1, HEX 1, DmHex1, CG1318, Hexo1, HEXO1" "IPR025705:Beta-hexosaminidase, IPR015883:Glycoside hydrolase family 20, catalytic domain, IPR017853:Glycoside hydrolase superfamily, IPR029018:Chitobiase/beta-hexosaminidase domain 2-like, IPR029019:Beta-hexosaminidase, eukaryotic type, N-terminal" CG1318 11-Aug-17 DroID_v2017_08 "Drer\hexa, Drer\hexb" - Cele\hex-1 Xtro\hexb "Mmus\Hexb, Mmus\Hexa" "Hsap\HEXB, Hsap\HEXA" "viable,fertile" FBgn0050447 CG30447 - http://flybase.org/reports/FBgn0050447 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30447 - CG30447 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028339 l(1)G0242 lethal (1) G0242 http://flybase.org/reports/FBgn0028339 gene - - - l(1)G0242 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023067 l(1)20Aj lethal (1) 20Aj http://flybase.org/reports/FBgn0023067 - gene - - - "1200E7b, l(1)20Aj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026564 CG1162 - http://flybase.org/reports/FBgn0026564 - protein_coding_gene - - - "ORF1, BG:DS00276.8, CG1162" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0014333 l(3)ry99 lethal (3) ry99 http://flybase.org/reports/FBgn0014333 - gene - - - l(3)ry99 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032338 CG16854 - http://flybase.org/reports/FBgn0032338 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" - "CG16854, gi7297815" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG16854 11-Aug-17 DroID_v2017_08 - - "Cele\Y38A10A.2, Cele\F07C3.3, Cele\K03A11.4, Cele\Y41E3.1, Cele\F32G8.2, Cele\F32D8.2, Cele\M03F8.5, Cele\Y73F8A.35, Cele\T23E1.1, Cele\F10C2.3, Cele\R03G8.3, Cele\R03G8.1, Cele\T07G12.3, Cele\F15H10.7" - - - "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0002343 l(3)87Bl lethal (3) 87Bl http://flybase.org/reports/FBgn0002343 - gene - - - "l(3)ck24, l(3)87Bl" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020800 negro negro http://flybase.org/reports/FBgn0020800 - gene - - - "ne, negro" - - 11-Aug-17 DroID_v2017_08 - - - - - - body color defective FBgn0065414 l(2)SH1557 lethal (2) SH1557 http://flybase.org/reports/FBgn0065414 gene - - - "l(2)SH1557, l(2)SH2 1557" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266421 RPA3 Replication protein A3 http://flybase.org/reports/FBgn0266421 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR013970 DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR013970 DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR013970 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR013970 neuronal stem cell population maintenance ; GO:0097150 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG15220, RPA3, BcDNA:RH55360, l(1)G0241" "IPR012340:Nucleic acid-binding, OB-fold, IPR013970:Replication factor A protein 3" CG15220 11-Aug-17 DroID_v2017_08 Drer\rpa3 - - Xtro\rpa3 Mmus\Rpa3 Hsap\RPA3 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,recessive,lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,lamina anlage,medulla anlage,larval outer optic anlage,somatic clone" FBgn0041834 Eth-AR308 Eth-AR308 http://flybase.org/reports/FBgn0041834 gene - - - "Eth[AR]308, Eth-AR308" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0039564 CG5527 - http://flybase.org/reports/FBgn0039564 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG5527 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG5527 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\ece2b, Drer\phex, Drer\mmel1" - "Cele\nep-19, Cele\nep-6, Cele\nep-16, Cele\nep-23, Cele\nep-12, Cele\nep-5, Cele\nep-2, Cele\nep-7, Cele\nep-26, Cele\nep-9, Cele\nep-17, Cele\nep-13, Cele\nep-8, Cele\nep-18, Cele\nep-20, Cele\nep-21, Cele\nep-10, Cele\nep-24, Cele\nep-22, Cele\nep-3" "Xtro\ecel1, Xtro\mmel1, Xtro\ece1, Xtro\ece2" "Mmus\Mmel1, Mmus\Ecel1, Mmus\Phex, Mmus\Ece1, Mmus\Ece2, Mmus\Mme, Mmus\Kel" "Hsap\ECEL1, Hsap\ECE2, Hsap\KEL, Hsap\ECE1, Hsap\MMEL1, Hsap\MME, Hsap\PHEX" FBgn0035686 Cpr65Az Cuticular protein 65Az http://flybase.org/reports/FBgn0035686 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr65Az, CG12330, DmelCpr65Az" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG12330 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0263203 T:Mito-Tom20 Mitochondrial targeting motif of Tom20 http://flybase.org/reports/FBgn0263203 engineered_tag - - - "T:Mito-Tom20, T:Tom20" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010692 l(2)s3997 lethal (2) s3997 http://flybase.org/reports/FBgn0010692 - gene - - - l(2)s3997 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0036956 CG13813 - http://flybase.org/reports/FBgn0036956 protein_coding_gene - - - CG13813 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG13813 11-Aug-17 DroID_v2017_08 - - "Cele\Y45G12C.4, Cele\F56A4.5, Cele\E02C12.9, Cele\H06H21.8, Cele\dhs-27, Cele\C29F7.2, Cele\E02C12.6, Cele\E02C12.10, Cele\F59B1.10, Cele\nhr-246, Cele\T16G1.5, Cele\T16G1.6, Cele\C29F7.1, Cele\F49C12.7, Cele\E02C12.8, Cele\T16G1.3, Cele\F59B1.8, Cele\H37A05.2" - - - viable FBgn0065214 l(2)SH2255 lethal (2) SH2255 http://flybase.org/reports/FBgn0065214 gene - - - "l(2)SH2255, l(2)SH2 2255" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003637 su(vg) suppressor of vestigial http://flybase.org/reports/FBgn0003637 - gene - - - su(vg) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067874 Mod(Prat:bw)3-12 Mod(Prat:bw)3-12 http://flybase.org/reports/FBgn0067874 gene - - - "Mod-3-12, Mod(Prat:bw)3-12" - - 11-Aug-17 DroID_v2017_08 - - - - - - suppressor of variegation FBgn0054033 CG34033 - http://flybase.org/reports/FBgn0054033 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "BP1078, HDC05479, CG34033" "IPR016187:C-type lectin fold, IPR016186:C-type lectin-like/link domain, IPR001304:C-type lectin-like" CG34033 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-232p21.6, Drer\si:ch73-343l4.2, Drer\si:ch211-133n4.7, Drer\si:ch211-170d8.5, Drer\zmp:0000000937, Drer\si:dkey-187i8.2, Drer\illr4, Drer\illr2, Drer\illr1, Drer\zmp:0000000924, Drer\LOC101884526, Drer\LOC101884413, Drer\si:ch73-111e15.1, Drer\si:dkey-61f9.2, Drer\LOC101886537, Drer\si:ch73-122g19.1, Drer\zgc:174904, Drer\si:ch73-361h17.1, Drer\si:dkey-61f9.1, Drer\si:ch73-343l4.8, Drer\si:ch211-214k5.3, Drer\si:ch211-283g2.3, Drer\si:ch73-86n18.1, Drer\cd209, Drer\LOC100007376, Drer\LOC100331140, Drer\illr3" - "Cele\clec-160, Cele\F56A4.2, Cele\clec-209, Cele\C25G4.17, Cele\clec-198, Cele\clec-184, Cele\clec-185, Cele\clec-149, Cele\clec-199, Cele\clec-202" - "Mmus\Cd209b, Mmus\Clec4a1, Mmus\Cd207, Mmus\Clec4a3, Mmus\Cd209c, Mmus\Cd209e, Mmus\Clec4d, Mmus\Clec4b1, Mmus\Clec10a, Mmus\Mgl2, Mmus\Clec4a2, Mmus\Fcer2a, Mmus\Clec4b2, Mmus\Clec4a4, Mmus\Cd209g, Mmus\Clec4g, Mmus\Clec4f, Mmus\Cd209a, Mmus\Clec4n, Mmus\Clec4e, Mmus\Asgr2, Mmus\Asgr1, Mmus\Cd209f, Mmus\Cd209d, Mmus\Gm156" "Hsap\CLEC4G, Hsap\CLEC10A, Hsap\CLEC4F, Hsap\CD207, Hsap\CLEC4E, Hsap\CLEC4C, Hsap\CD209, Hsap\FCER2, Hsap\CLEC17A, Hsap\CLEC4D, Hsap\ASGR1, Hsap\CLEC6A, Hsap\CLEC4A, Hsap\ASGR2, Hsap\CLEC4M" FBgn0030493 CG15756 - http://flybase.org/reports/FBgn0030493 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model CG15756 IPR000618:Insect cuticle protein CG15756 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - "viable,visible" trichogen cell FBgn0002115 l(2)bw lethal (2) bw http://flybase.org/reports/FBgn0002115 - gene - - - l(2)bw - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005020 dke dark eye http://flybase.org/reports/FBgn0005020 - gene - - - "dke-c, dke" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0065584 l(2)SH0921 lethal (2) SH0921 http://flybase.org/reports/FBgn0065584 gene - - - "l(2)SH0921, l(2)SH2 0921" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036485 FucTA FucTA http://flybase.org/reports/FBgn0036485 protein_coding_gene "alpha-(1->3)-fucosyltransferase activity ; GO:0046920 | inferred from mutant phenotype 1,3-alpha-L-fucosidase activity ; GO:0033932 | inferred from mutant phenotype alpha-(1->3)-fucosyltransferase activity ; GO:0046920 | inferred from direct assay glycoprotein 3-alpha-L-fucosyltransferase activity ; GO:0018392 | inferred from direct assay fucosyltransferase activity ; GO:0008417 | inferred from direct assay" nervous system development ; GO:0007399 | inferred from mutant phenotype protein glycosylation ; GO:0006486 | inferred from mutant phenotype protein glycosylation ; GO:0006486 | inferred from direct assay N-glycan fucosylation ; GO:0036071 | inferred from mutant phenotype Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000231531 Golgi medial cisterna ; GO:0005797 | inferred from direct assay "CG6869, anon-EST:Posey285, FucTA, Dm alpha1,3-FucT, fucTA" "IPR001503:Glycosyl transferase family 10, IPR031481:Fucosyltransferase, N-terminal" CG6869 11-Aug-17 DroID_v2017_08 "Drer\fut9b, Drer\fut10, Drer\fut9d, Drer\zgc:103510, Drer\zgc:173737, Drer\si:ch1073-440p11.2, Drer\ft2, Drer\fut11, Drer\fut7, Drer\zgc:165519, Drer\zgc:136963, Drer\zgc:165582, Drer\fut9a, Drer\ft1, Drer\ctu1, Drer\zgc:112433" - "Cele\fut-1, Cele\fut-5, Cele\fut-6, Cele\fut-3, Cele\C07E3.8, Cele\fut-4" "Xtro\LOC100497863, Xtro\fut11, Xtro\fut4, Xtro\fut10, Xtro\LOC100485897, Xtro\fut9, Xtro\LOC100498016, Xtro\fut3, Xtro\fut5, Xtro\fut6" "Mmus\Fut10, Mmus\Fut11, Mmus\Fut4, Mmus\Fut9, Mmus\Fut7" "Hsap\FUT7, Hsap\FUT11, Hsap\FUT4, Hsap\FUT10, Hsap\FUT6, Hsap\FUT3, Hsap\FUT9, Hsap\FUT5" "viable,fertile,neuroanatomy defective,visible" "ventral nerve cord,embryonic/larval glial cell,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,wing margin,anterior crossvein,mesothoracic tergum" FBgn0034766 Obp59a Odorant-binding protein 59a http://flybase.org/reports/FBgn0034766 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "Obp58a, CG13517, 59a, Obp59a, DmelObp59a" IPR006170:Pheromone/general odorant binding protein CG13517 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264547 CR43926 - http://flybase.org/reports/FBgn0264547 non_protein_coding_gene - - - CR43926 - CR43926 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034001 mRpL41 mitochondrial ribosomal protein L41 http://flybase.org/reports/FBgn0034001 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q8IXM3 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AI912106 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q8IXM3 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AI912106 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q8IXM3 intracellular ribonucleoprotein complex ; GO:0030529 | inferred from sequence or structural similarity with UniProtKB:Q8IXM3 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AI912106 "CG12954, YmL27, BcDNA:RE19416, mRpL41" "IPR019189:Ribosomal protein L27/L41, mitochondrial" CG12954 11-Aug-17 DroID_v2017_08 Drer\mrpl41 Scer\MRPL27 Cele\mrpl-41 Xtro\mrpl41 "Mmus\Mrpl41, Mmus\LOC101055953" Hsap\MRPL41 "viable,visible" trichogen cell FBgn0040685 CG12587 - http://flybase.org/reports/FBgn0040685 protein_coding_gene - - - CG12587 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0022338 dnk deoxyribonucleoside kinase http://flybase.org/reports/FBgn0022338 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002624 deoxynucleoside kinase activity ; GO:0019136 | inferred from direct assay thymidine kinase activity ; GO:0004797 | inferred from sequence or structural similarity with UniProtKB:O00142 kinase activity ; GO:0016301 | inferred from direct assay TMP biosynthetic process ; GO:0006230 | inferred from sequence or structural similarity with UniProtKB:O00142 nucleoside diphosphate phosphorylation ; GO:0006165 | inferred from direct assay nucleotide phosphorylation ; GO:0046939 | inferred from direct assay phosphorylation ; GO:0016310 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O00142 cytoplasm ; GO:0005737 | inferred from direct assay "DmdNK, Dm-dNK, dNK, DM-dNK, CG5452, dnk, DNK" "IPR002624:Deoxynucleoside kinase, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031314:Deoxynucleoside kinase domain" CG5452 11-Aug-17 DroID_v2017_08 "Drer\dguok, Drer\tk2, Drer\dck, Drer\zgc:110540" - "Cele\K01A12.4, Cele\M02D8.6" "Xtro\dguok, Xtro\tk2, Xtro\dck.1, Xtro\dck.2" "Mmus\Dck, Mmus\Dguok, Mmus\Tk2" "Hsap\DGUOK, Hsap\TK2, Hsap\DCK" "locomotor behavior defective,viable" FBgn0031086 fd19B forkhead domain 19B http://flybase.org/reports/FBgn0031086 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR030456 neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "Dmcg9571, fd19B, CG9571" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG9571 11-Aug-17 DroID_v2017_08 "Drer\foxi3a, Drer\foxg1c, Drer\foxj3, Drer\foxj2, Drer\foxg1d, Drer\foxi2, Drer\foxg1b, Drer\foxi1, Drer\foxi3b, Drer\foxg1a" "Scer\FHL1, Scer\FKH2, Scer\HCM1, Scer\FKH1" "Cele\fkh-2, Cele\fkh-9" "Xtro\foxe3, Xtro\foxi2, Xtro\foxi4.2, Xtro\foxj2, Xtro\foxi4.1, Xtro\foxi1" "Mmus\Foxi2, Mmus\Foxg1, Mmus\Foxj2, Mmus\Foxi1, Mmus\Foxj3" "Hsap\FOXJ2, Hsap\FOXI1, Hsap\FOXG1, Hsap\FOXI2, Hsap\FOXJ3" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0259581 GG01303 - http://flybase.org/reports/FBgn0259581 gene - - - GG01303 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0083013 snoRNA:Psi28S-1060 snoRNA:Psi28S-1060 http://flybase.org/reports/FBgn0083013 snoRNA_gene - - - "snoRNA:Psi28S-1060, Psi28S-1060, psi28S-1060, Psi 28S-1060, CR34591" - CR34591 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031779 CG9175 - http://flybase.org/reports/FBgn0031779 protein_coding_gene GTPase binding ; GO:0051020 | inferred from biological aspect of ancestor with PANTHER:PTN000590366 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000590366 Sar guanyl-nucleotide exchange factor activity ; GO:0005090 | inferred from biological aspect of ancestor with PANTHER:PTN000590366 regulation of COPII vesicle coating ; GO:0003400 | inferred from biological aspect of ancestor with PANTHER:PTN000590366 cell morphogenesis ; GO:0000902 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000590366 endomembrane system ; GO:0012505 | inferred from direct assay "CG9175, Sec12" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG9175 11-Aug-17 DroID_v2017_08 Drer\preb "Scer\SED4, Scer\SEC12" Cele\sec-12 Xtro\preb Mmus\Preb Hsap\PREB "viable,fertile" FBgn0053389 5SrRNA:CR33389 5SrRNA:CR33389 http://flybase.org/reports/FBgn0053389 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33389, 5SrRNA:CR33389" - CR33389 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036417 CG7906 - http://flybase.org/reports/FBgn0036417 protein_coding_gene - - - CG7906 IPR002350:Kazal domain CG7906 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0022267 l(2)k00605b lethal (2) k00605b http://flybase.org/reports/FBgn0022267 - gene - - - "l(2)k00605, l(2)k00605b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053442 5SrRNA:CR33442 5SrRNA:CR33442 http://flybase.org/reports/FBgn0053442 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33442, 5SrRNA:CR33442" - CR33442 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037397 CR1075 - http://flybase.org/reports/FBgn0037397 pseudogene_attribute - - - "CG1075, CR1075" - CR1075 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC12144 K -0.162931853 0.357908652 -0.151925003 0.242523791 -1.532099172 -1.46805054 FBgn0015003 ACE1 Amplification-control-element-on-1 http://flybase.org/reports/FBgn0015003 - region - - - ACE1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0277419 l(3)psg15 - http://flybase.org/reports/FBgn0277419 gene - - - "l(3)psg15, psg15" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001650 l(1)ds2 lethal (1) discs small 2 http://flybase.org/reports/FBgn0001650 - gene - - - "l(1)d.sml.-2, l(1)ds2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033897 Rcd1 Reduction in Cnn dots 1 http://flybase.org/reports/FBgn0033897 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR002925 germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs neurogenesis ; GO:0022008 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay NSL complex ; GO:0044545 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000320010 "NSL3, CG8233, Rcd1, cg8233, Nsl3" "IPR029058:Alpha/Beta hydrolase fold, IPR026555:KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein, IPR002925:Dienelactone hydrolase" CG8233 11-Aug-17 DroID_v2017_08 "Drer\kansl3, Drer\tex30" - "Cele\F54D11.4, Cele\sumv-2" "Xtro\tex30, Xtro\kansl3" Mmus\Kansl3 Hsap\KANSL3 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,female sterile" "embryonic/larval neuroblast,ganglion mother cell,epithelium,female germline cyst" DRSC07116 E -0.137680091 0.256948652 0.321711811 -3.439579811 -0.795444286 -0.709817657 FBgn0264480 CR43888 - http://flybase.org/reports/FBgn0264480 non_protein_coding_gene - - - CR43888 - CR43888 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067774 fragile-locus-B fragile locus B http://flybase.org/reports/FBgn0067774 gene molecular_function ; GO:0003674 | no biological data available egg activation ; GO:0007343 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fragile-locus-B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" FBgn0046641 anon-38D.32 anon-38D.32 http://flybase.org/reports/FBgn0046641 gene - - - "38D.32, anon-38D.32" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264740 CG43998 - http://flybase.org/reports/FBgn0264740 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of lipid metabolic process ; GO:0019216 | inferred from biological aspect of ancestor with PANTHER:PTN000281649 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000281649 "CG43998, CR43998, BcDNA:AT03227, CG13602" IPR010754:Optic atrophy 3-like CG43998 11-Aug-17 DroID_v2017_08 Drer\opa3 - Cele\H43I07.1 Xtro\opa3 Mmus\Opa3 Hsap\OPA3 FBgn0085752 CR40594 - http://flybase.org/reports/FBgn0085752 rRNA_gene - - - CR40594 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060986 l(3)S028113 lethal (3) S028113 http://flybase.org/reports/FBgn0060986 gene - - - "0281/13, l(3)S028113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0261989 CG42807 - http://flybase.org/reports/FBgn0261989 protein_coding_gene - - - "CG42807, CG13335, CG6183" - CG42807 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005467 l(1)ts136 lethal (1) ts136 http://flybase.org/reports/FBgn0005467 - gene - - - l(1)ts136 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0262166 calypso calypso http://flybase.org/reports/FBgn0262166 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay "ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR001578 monoubiquitinated histone H2A deubiquitination ; GO:0035522 | inferred from direct assay specification of segmental identity, abdomen ; GO:0007385 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype" PR-DUB complex ; GO:0035517 | inferred from direct assay inferred from physical interaction with Asx nuclear chromatin ; GO:0000790 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000063280 nucleus ; GO:0005634 | inferred from direct assay "CG8445, BAP1, calypso, Q7K5N4, bap1, Calypso" "IPR001578:Peptidase C12, ubiquitin carboxyl-terminal hydrolase" CG8445 11-Aug-17 DroID_v2017_08 "Drer\bap1, Drer\uchl5" - - "Xtro\bap1, Xtro\uchl5" "Mmus\Bap1, Mmus\Uchl5" "Hsap\BAP1, Hsap\UCHL5" FBgn0011998 tRNA:Val-CAC-2-2 transfer RNA:Valine-CAC 2-2 http://flybase.org/reports/FBgn0011998 "FBan0031592, FBgn0003853, FBgn0011997, FBgn0051592, FBgn0060023" tRNA_gene GUG codon-amino acid adaptor activity ; GO:0033452 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033452 cytosol ; GO:0005829 | inferred by curator from GO:0033452 "valine tRNA, tRNA[Val][[3b]], tRNA[Val3b], Val-3b, AE002699.trna13-ValCAC, tRNA:V3b, tRNA:V:CAC:AE002699-d, CR31592, tRNA:val3b:84Da, chr3R.trna6-ValCAC, tRNA:Val-CAC-2-2, tRNA:V3b:84Da, tRNA-Val-CAC-2-2, GUG" - CR31592 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019966 Khc::sif Khc::sif http://flybase.org/reports/FBgn0019966 - engineered_fusion_gene - - - Khc::sif - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "synapseelav.PLu,bouton,abdominal segmental nerve" FBgn0050259 CG30259 - http://flybase.org/reports/FBgn0050259 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13523, CG13522, CG30259" - CG30259 11-Aug-17 DroID_v2017_08 Drer\ccdc65 - - Xtro\ccdc65 Mmus\Ccdc65 Hsap\CCDC65 "viable,fertile,visible" "trichogen cell,supernumerary" FBgn0263354 CG42784 - http://flybase.org/reports/FBgn0263354 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG16850/CG31846, CG42784, Dm_2L:67149, BcDNA:GH04046, CR31846, CG31846, CG16850, CG16851, BcDNA:HL01958, CG31847, mdcds_2231" IPR015943:WD40/YVTN repeat-like-containing domain CG42784 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22272 I -0.260193243 2.017581191 0.038612236 -0.131700202 -0.320753689 1.136056229 FBgn0028708 Mst85C Mst85C http://flybase.org/reports/FBgn0028708 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG11993, Mst85C" - CG11993 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male viable DRSC16746 E 0.769796872 -0.661860353 -1.73194321 -0.013806641 0.334064922 0.627920243 FBgn0266097 CR44834 - http://flybase.org/reports/FBgn0266097 non_protein_coding_gene - - - CR44834 - CR44834 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260069 2L3390 - http://flybase.org/reports/FBgn0260069 gene - - - 2L3390 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0003099 PL(2)L4 Polygenic locus L4 wing vein http://flybase.org/reports/FBgn0003099 - gene - - - "PL(2)L4a, PL(2)L4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038685 CG14282 - http://flybase.org/reports/FBgn0038685 protein_coding_gene histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000599398 chromatin silencing at telomere ; GO:0006348 | inferred from biological aspect of ancestor with PANTHER:PTN000599398 Set1C/COMPASS complex ; GO:0048188 | inferred from biological aspect of ancestor with PANTHER:PTN000599398 CG14282 - CG14282 11-Aug-17 DroID_v2017_08 Drer\dydc2 - - - "Mmus\Dydc2, Mmus\Dydc1" "Hsap\DYDC1, Hsap\DYDC2" "viable,fertile" FBgn0060319 l(3)S147313 lethal (3) S147313 http://flybase.org/reports/FBgn0060319 gene - - - "1473/13, l(3)S147313" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0000329 clw clubwing http://flybase.org/reports/FBgn0000329 - gene - - - clw - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0065456 l(2)SH1386 lethal (2) SH1386 http://flybase.org/reports/FBgn0065456 gene - - - "l(2)SH1386, l(2)SH2 1386" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003265 Rnase2 Ribonuclease 2 http://flybase.org/reports/FBgn0003265 - gene - - - Rnase2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038445 CG14891 - http://flybase.org/reports/FBgn0038445 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14891, FBXL13" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR000504:RNA recognition motif domain" CG14891 11-Aug-17 DroID_v2017_08 "Drer\kdm2ab, Drer\zgc:158376, Drer\fbxl15, Drer\fbxl17, Drer\fbxl6, Drer\fbxl4, Drer\kdm2aa, Drer\si:dkey-192l18.9" "Scer\GRR1, Scer\RAD7" Cele\EEED8.10 "Xtro\fbxl4, Xtro\kdm2b, Xtro\fbxl19, Xtro\fbxl12" "Mmus\Lrrc29, Mmus\Fbxl14, Mmus\Fbxl17, Mmus\Fbxl19, Mmus\Fbxl21, Mmus\Kdm2a, Mmus\Fbxl6, Mmus\Kdm2b, Mmus\Fbxl4" "Hsap\KDM2B, Hsap\FBXL13, Hsap\FBXL19, Hsap\FBXL6, Hsap\FBXL17, Hsap\KDM2A, Hsap\LRRC29, Hsap\FBXL14, Hsap\FBXL4" viable FBgn0065167 l(3)SH032 lethal (3) SH032 http://flybase.org/reports/FBgn0065167 gene - - - "l(3)SH032, l(2)SH3 032" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262966 CG43277 - http://flybase.org/reports/FBgn0262966 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from sequence model CG43277 - CG43277 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010104 cex central complex http://flybase.org/reports/FBgn0010104 - gene - adult walking behavior ; GO:0007628 | traceable author statement behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype - cex - - 11-Aug-17 DroID_v2017_08 - - - - - - "locomotor behavior defective,recessive,viable,behavior defective,neuroanatomy defective" "protocerebral bridge,fan-shaped body,ellipsoid body,nodulus" FBgn0261789 SmD2 Small ribonucleoprotein particle protein SmD2 http://flybase.org/reports/FBgn0261789 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:11159 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with UniProtKB:Q02260 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004265 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype spliceosomal snRNP assembly ; GO:0000387 | inferred from biological aspect of ancestor with PANTHER:PTN000299609" precatalytic spliceosome ; GO:0071011 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000004265 U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000299609 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with UniProtKB:Q02260 U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000299609 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000004265 U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000299609 U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000299609 "CG1249, snRNP2, SmD2, BcDNA:LD03002, snRNP D2, dD2, SMD2_DROME, D2-Sm" "IPR027248:Small nuclear ribonucleoprotein Sm D2, IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain" CG1249 11-Aug-17 DroID_v2017_08 Drer\snrpd2 Scer\SMD2 Cele\snr-4 Xtro\snrpd2 Mmus\Snrpd2 Hsap\SNRPD2 DRSC12536 IE -0.339903988 1.676149335 -3.723763331 -0.532462112 -0.079102399 -0.541013847 FBgn0021989 l(2)k09617 lethal (2) k09617 http://flybase.org/reports/FBgn0021989 - gene - - - l(2)k09617 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265577 CR44404 - http://flybase.org/reports/FBgn0265577 non_protein_coding_gene - - - CR44404 - CR44404 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020575 anon-59Cj anon-59Cj http://flybase.org/reports/FBgn0020575 - gene - - - anon-59Cj - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031245 CG3625 - http://flybase.org/reports/FBgn0031245 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006838 endomembrane system ; GO:0012505 | inferred from direct assay CG3625 IPR006838:FAR-17a/AIG1-like protein CG3625 11-Aug-17 DroID_v2017_08 "Drer\zgc:112175, Drer\aig1, Drer\LOC100537455, Drer\mybl2a" Scer\YHR140W "Cele\cTel55X.1, Cele\C37E2.3, Cele\C37E2.2" "Xtro\myo15a, Xtro\LOC100495442" "Mmus\Aig1, Mmus\Adtrp" "Hsap\AIG1, Hsap\ADTRP" "visible,partially lethal - majority die,some die during pupal stage,viable" mesothoracic tergum FBgn0035831 CG8038 - http://flybase.org/reports/FBgn0035831 protein_coding_gene ribonuclease P activity ; GO:0004526 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000331370 ribonuclease P RNA binding ; GO:0033204 | inferred from biological aspect of ancestor with PANTHER:PTN000331370 ribonuclease MRP activity ; GO:0000171 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000331370 "mRNA cleavage ; GO:0006379 | inferred from electronic annotation with InterPro:IPR002730, InterPro:IPR016848 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR002730, InterPro:IPR016848 cellular response to starvation ; GO:0009267 | inferred from expression pattern rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000331370" nucleolar ribonuclease P complex ; GO:0005655 | inferred from electronic annotation with InterPro:IPR016848 ribonuclease P complex ; GO:0030677 | inferred from biological aspect of ancestor with PANTHER:PTN000331370 ribonuclease MRP complex ; GO:0000172 | inferred from biological aspect of ancestor with PANTHER:PTN000331370 "BcDNA:LD45688, anon-WO0172774.38, CG8038" "IPR002730:Ribonuclease P/MRP, subunit p29, IPR016848:Ribonuclease P/MRP, p29 subunit, IPR023534:Rof/RNase P-like" CG8038 11-Aug-17 DroID_v2017_08 Drer\pop4 "Scer\SLK19, Scer\POP4" Cele\C15C6.4 Xtro\pop4 Mmus\Pop4 Hsap\POP4 "viable,visible" trichogen cell FBgn0020433 GMR Glass Multimer Reporter http://flybase.org/reports/FBgn0020433 - engineered_region - - - GMR - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0278601 Hsap\ARRB2::TEV\NIa - http://flybase.org/reports/FBgn0278601 engineered_fusion_gene - - - "Hsap\ARRB2::Zzzz\NIa, Hsap\ARRB2::TEV\NIa, ARRB2::Zzzz\NIa, ARRB2::TEV\NIa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259612 B0891 - http://flybase.org/reports/FBgn0259612 gene - - - B0891 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing vein L3,wing" FBgn0025467 tin::Mmus\Nkx2-5 Nkx2-5 http://flybase.org/reports/FBgn0025467 - engineered_fusion_gene - - - tin::Mmus\Nkx2-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016635 E(gl)3C Enhancer of glass 3C http://flybase.org/reports/FBgn0016635 - gene - - - E(gl)3C - - 11-Aug-17 DroID_v2017_08 - - - - - - rhabdomere FBgn0035753 RpL18 Ribosomal protein L18 http://flybase.org/reports/FBgn0035753 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000039, InterPro:IPR021132 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement" cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "CG8615, RpL18, RpL18e, Rp L18" "IPR000039:Ribosomal protein L18e, IPR021131:Ribosomal protein L18e/L15P, IPR021132:Ribosomal protein L18e, conserved site" CG8615 11-Aug-17 DroID_v2017_08 "Drer\gk5, Drer\rpl18" "Scer\RPL18A, Scer\RPL18B" "Cele\C55B6.1, Cele\rpl-18" Xtro\rpl18 "Mmus\Gk5, Mmus\Rpl18" "Hsap\RPL18, Hsap\GK5" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC22323 IEK 5.591919198 -0.823850362 4.872171069 -5.390907854 2.780343758 4.103543711 FBgn0031955 CG14535 - http://flybase.org/reports/FBgn0031955 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 ATPase activity ; GO:0016887 | NOT inferred from sequence or structural similarity with MGI:MGI:2447072 microtubule motor activity ; GO:0003777 | NOT inferred from sequence or structural similarity with MGI:MGI:2447072 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with MGI:MGI:2447072 microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | NOT inferred from sequence or structural similarity with MGI:MGI:2447072 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 "CG14535, KIF26, DmKIF26, KIF26A/B" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG14535 11-Aug-17 DroID_v2017_08 "Drer\LOC100333558, Drer\kif15, Drer\si:dkey-86l18.8, Drer\LOC100331925, Drer\kif26bb, Drer\kif26aa, Drer\kif26ba, Drer\kif17" Scer\SMY1 Cele\vab-8 "Xtro\kif9, Xtro\kif3a, Xtro\kif15, Xtro\kif26a" "Mmus\Kif26a, Mmus\Kif12, Mmus\Kif17, Mmus\Kif9, Mmus\Kif26b, Mmus\Kif15, Mmus\Kif6" "Hsap\KIF12, Hsap\KIF26B, Hsap\KIF15, Hsap\KIF9, Hsap\KIF3A, Hsap\KIF6, Hsap\KIF26A, Hsap\KIF17" FBgn0263575 mir-4912 mir-4912 stem loop http://flybase.org/reports/FBgn0263575 miRNA_gene - - - "mir-4912, dme-mir-4912, CR43560" - CR43560 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011076 l(1)Q30 lethal (1) Q30 http://flybase.org/reports/FBgn0011076 FBgn0010210 gene - - - l(1)Q30 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265016 S1364-03 - http://flybase.org/reports/FBgn0265016 gene - - - S1364-03 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267277 CR45713 - http://flybase.org/reports/FBgn0267277 non_protein_coding_gene - - - CR45713 - CR45713 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050466 CG30466 - http://flybase.org/reports/FBgn0050466 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG30466, FBXO19" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG30466 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044812 TotC Turandot C http://flybase.org/reports/FBgn0044812 protein_coding_gene - cellular response to heat ; GO:0034605 | inferred from expression pattern response to heat ; GO:0009408 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern cellular response to UV ; GO:0034644 | inferred from expression pattern response to UV ; GO:0009411 | inferred from direct assay response to oxidative stress ; GO:0006979 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with TotA "TotC, tot, totC, CG31508, TOTc, Turandot C" IPR010825:Stress-inducible humoral factor Turandot CG31508 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0011603 ine inebriated http://flybase.org/reports/FBgn0011603 FBgn0020253 protein_coding_gene photoreceptor activity ; GO:0009881 | inferred from electronic annotation with InterPro:IPR002944 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 osmosensor activity ; GO:0005034 | inferred from mutant phenotype neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence or structural similarity with SerT inferred from sequence or structural similarity with HGNC:11045 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model "neurotransmitter transport ; GO:0006836 | inferred from electronic annotation with InterPro:IPR000175, InterPro:IPR002944 multicellular organismal water homeostasis ; GO:0050891 | inferred from mutant phenotype glial cell growth ; GO:0042065 | inferred from mutant phenotype neurotransmitter transport ; GO:0006836 | inferred from sequence model transmission of nerve impulse ; GO:0019226 | inferred from mutant phenotype response to water deprivation ; GO:0009414 | inferred from mutant phenotype regulation of response to osmotic stress ; GO:0047484 | inferred from mutant phenotype transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 perineurial glial growth ; GO:0042066 | inferred from genetic interaction with poe inferred from genetic interaction with Nf1" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with SerT inferred from sequence or structural similarity with HGNC:11045 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 basolateral plasma membrane ; GO:0016323 | inferred from direct assay "CG15444, rosA, ine/rosA, ine, CG15444d, DMINE" "IPR000175:Sodium:neurotransmitter symporter, IPR002944:Sodium:neurotransmitter symporter, inebriated" CG15444 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-225b11.1, Drer\slc6a6a, Drer\si:ch211-132b12.3, Drer\slc6a13, Drer\slc6a11a, Drer\zgc:158225, Drer\slc6a13l, Drer\slc6a2, Drer\slc6a6b, Drer\slc6a1b, Drer\slc6a8, Drer\si:ch211-117c9.5, Drer\slc6a5, Drer\slc6a18, Drer\slc6a14, Drer\slc6a13, Drer\slc6a16b, Drer\slc6a15, Drer\slc6a1l, Drer\slc6a19b, Drer\slc6a17, Drer\slc6a19a.1, Drer\slc6a4b, Drer\zgc:174946, Drer\slc6a9, Drer\si:ch211-283g2.1, Drer\si:ch211-132b12.6, Drer\slc6a16a, Drer\si:ch211-132b12.1, Drer\si:ch211-132b12.2, Drer\slc6a4a, Drer\slc6a1a" - "Cele\snf-11, Cele\snf-6, Cele\dat-1, Cele\mod-5, Cele\snf-3" "Xtro\slc6a3, Xtro\slc6a14.2, Xtro\slc6a16, Xtro\slc6a1, Xtro\slc6a9, Xtro\slc6a6, Xtro\slc6a19, Xtro\slc6a12, Xtro\slc6a15, Xtro\slc6a7, Xtro\slc6a5, Xtro\slc6a17, Xtro\slc6a13, Xtro\slc6a4, Xtro\LOC100127682, Xtro\slc6a8, Xtro\slc6a2" "Mmus\Slc6a8, Mmus\Slc6a3, Mmus\Slc6a20b, Mmus\Slc6a6, Mmus\Slc6a7, Mmus\Slc6a14, Mmus\Slc6a4, Mmus\Slc6a18, Mmus\Slc6a15, Mmus\Slc6a1, Mmus\Slc6a13, Mmus\Slc6a20a, Mmus\Slc6a17, Mmus\Slc6a12, Mmus\Slc6a11, Mmus\Slc6a5, Mmus\Slc6a19, Mmus\Slc6a9, Mmus\Slc6a2" "Hsap\SLC6A9, Hsap\SLC6A1, Hsap\SLC6A15, Hsap\SLC6A14, Hsap\SLC6A6, Hsap\SLC6A13, Hsap\SLC6A3, Hsap\SLC6A12, Hsap\SLC6A4, Hsap\SLC6A11, Hsap\SLC6A19, Hsap\SLC6A17, Hsap\SLC6A2, Hsap\SLC6A20, Hsap\SLC6A18, Hsap\SLC6A8, Hsap\SLC6A5" " embryonic stage | stage >=13 , embryonic stage | stage >8 , embryonic stage | late , adult stage , embryonic stage | cellular blastoderm " " embryonic/larval midgut

, head | restricted

, inclusive hindgut primordium

, Malpighian tubule

, garland cell

, tracheal pit

, embryonic/larval foregut

,

ubiquitous , embryonic nervous system

, ventral nervous system | segmentally repeated

, pharyngeal muscle

, anal plate

" "viable,fertile,chemical sensitive,wild-type,behavior defective,paralytic,heat sensitive" FBgn0266196 CR44891 - http://flybase.org/reports/FBgn0266196 non_protein_coding_gene - - - CR44891 - CR44891 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022331 fs(3)167 fs(3)167 http://flybase.org/reports/FBgn0022331 - gene - - - "fs167, fs(3)167" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034945 CG10904 - http://flybase.org/reports/FBgn0034945 protein_coding_gene - - - CG10904 IPR006578:MADF domain CG10904 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030370 Uch-L5R Uch-L5-related http://flybase.org/reports/FBgn0030370 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with Uch-L5 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from biological aspect of ancestor with PANTHER:PTN000063280 protein deubiquitination ; GO:0016579 | inferred from biological aspect of ancestor with PANTHER:PTN000063280 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with Uch-L5 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity with Uch-L5 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000063280 proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with Uch-L5 "CG1950, Uch-L5R, Uch37R" "IPR001578:Peptidase C12, ubiquitin carboxyl-terminal hydrolase, IPR017390:Ubiquitinyl hydrolase, UCH37 type" CG1950 11-Aug-17 DroID_v2017_08 "Drer\uchl5, Drer\bap1" - Cele\ubh-4 "Xtro\bap1, Xtro\uchl5" "Mmus\Bap1, Mmus\Uchl5" "Hsap\BAP1, Hsap\UCHL5" FBgn0013716 l(3)neo44 lethal (3) neo44 http://flybase.org/reports/FBgn0013716 FBgn0020266 gene - - - "neo44, l(3)neo44" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010151 l(3)R115 lethal of Roberts 115 http://flybase.org/reports/FBgn0010151 - gene - - - "l(3)B115, l(3)R115" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0027611 LManII Lysosomal alpha-mannosidase II http://flybase.org/reports/FBgn0027611 - protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR015341 alpha-mannosidase activity ; GO:0004559 | inferred from direct assay mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from direct assay" protein deglycosylation ; GO:0006517 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 mannose metabolic process ; GO:0006013 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 extracellular region ; GO:0005576 | inferred from direct assay "dLMII, BcDNA:GH02419, CG6206, LManII, dLM408, dLM, LM, LM408, dLManII" "IPR000602:Glycoside hydrolase family 38, N-terminal domain, IPR011013:Galactose mutarotase-like domain, IPR011682:Glycosyl hydrolase family 38, C-terminal, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR015341:Glycoside hydrolase family 38, central domain, IPR027291:Glycoside hydrolase 38/57, N-terminal domain, IPR028995:Glycoside hydrolase families 57/38, central domain" CG6206 11-Aug-17 DroID_v2017_08 "Drer\man2b1, Drer\man2a2, Drer\man2b2" Scer\AMS1 "Cele\aman-2, Cele\aman-1" "Xtro\man2b1, Xtro\man2a1, Xtro\man2b2, Xtro\man2a2" "Mmus\Man2a2, Mmus\Man2b2, Mmus\Man2b1, Mmus\Man2c1, Mmus\Man2a1" "Hsap\MAN2B2, Hsap\MAN2C1, Hsap\MAN2A2, Hsap\MAN2A1, Hsap\MAN2B1" viable FBgn0004021 wp warped http://flybase.org/reports/FBgn0004021 - gene - - - wp - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,recessive,male sterile,visible,dominant" FBgn0052601 betaNACtes3 "Nascent-associated complex beta-subunit-like, testis 3" http://flybase.org/reports/FBgn0052601 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG9404, betaNACtes3, CG32601" IPR002715:Nascent polypeptide-associated complex NAC domain CG32601 11-Aug-17 DroID_v2017_08 "Drer\tab3, Drer\btf3, Drer\btf3l4, Drer\tab2" "Scer\BTT1, Scer\WWM1, Scer\EGD1, Scer\YML020W" Cele\icd-1 "Xtro\btf3, Xtro\btf3l4" "Mmus\Btf3l4, Mmus\Tab2, Mmus\Btf3, Mmus\Tab3" "Hsap\BTF3, Hsap\BTF3L4, Hsap\TAB2, Hsap\TAB3" FBgn0065236 l(2)SH2165 lethal (2) SH2165 http://flybase.org/reports/FBgn0065236 gene - - - "l(2)SH2165, l(2)SH2 2165" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060485 l(3)S110610 lethal (3) S110610 http://flybase.org/reports/FBgn0060485 gene - - - "1106/10, l(3)S110610" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0024674 l(2)k00503 lethal (2) k00503 http://flybase.org/reports/FBgn0024674 - gene - - - "5/3, l(2)k00503" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0052644 Mur11Da Mucin related 11Da http://flybase.org/reports/FBgn0052644 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern chorion ; GO:0042600 | inferred by curator from GO:0007304 extracellular matrix ; GO:0031012 | inferred from sequence model "Mur11Da, CG32644" - CG32644 11-Aug-17 DroID_v2017_08 - - Cele\ZC513.3 - - - FBgn0016672 Ipp Inositol polyphosphate 1-phosphatase http://flybase.org/reports/FBgn0016672 "FBgn0024890, FBgn0066012" protein_coding_gene "inositol-1,4-bisphosphate 1-phosphatase activity ; GO:0004441 | inferred from direct assay inferred from mutant phenotype" "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550 chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype inositol phosphate dephosphorylation ; GO:0046855 | inferred from direct assay inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available "ipp, CG3028, anon-WO02059370.48, Ipp, IPPase" "IPR000760:Inositol monophosphatase-like, IPR020550:Inositol monophosphatase, conserved site" CG3028 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-160o17.2, Drer\bpnt1" - - "Xtro\inpp1, Xtro\bpnt1" "Mmus\Bpnt1, Mmus\Inpp1" "Hsap\INPP1, Hsap\BPNT1" " adult stage , embryonic stage -- adult stage " " head

, retina

,

ubiquitous " "hyperactive,neurophysiology defective,viable" synapse FBgn0264996 CR44147 - http://flybase.org/reports/FBgn0264996 non_protein_coding_gene - - - CR44147 - CR44147 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044121 E(rst)B6 E(rst)B6 http://flybase.org/reports/FBgn0044121 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B6, E(rst)B6" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0085283 CG34254 - http://flybase.org/reports/FBgn0085283 protein_coding_gene - - - CG34254 IPR013320:Concanavalin A-like lectin/glucanase domain CG34254 11-Aug-17 DroID_v2017_08 - - Cele\Y53H1B.4 - - - FBgn0015388 flx female lethal on X http://flybase.org/reports/FBgn0015388 - gene - - - flx - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037554 DNApol-iota DNApol-iota http://flybase.org/reports/FBgn0037554 protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR017961 DNA-directed DNA polymerase activity ; GO:0003887 | inferred from direct assay inferred from mutant phenotype DNA-directed DNA polymerase activity ; GO:0003887 | non-traceable author statement translesion synthesis ; GO:0019985 | non-traceable author statement translesion synthesis ; GO:0019985 | inferred from sequence or structural similarity with HGNC:9182 inferred from direct assay - "AAF54198, drad30B, DNApol-iota, CG7602, Poliota, DNA Pol II-iota, DNApol-i, Dm-Poliota, DNA-pol iota" "IPR001126:UmuC domain, IPR017961:DNA polymerase, Y-family, little finger domain" CG7602 11-Aug-17 DroID_v2017_08 "Drer\poli, Drer\polk, Drer\esco1, Drer\polh, Drer\esco2" "Scer\REV1, Scer\RAD30, Scer\ECO1" "Cele\polk-1, Cele\polh-1, Cele\F08F8.4" Xtro\polk "Mmus\Esco2, Mmus\Esco1, Mmus\Polh, Mmus\Poli, Mmus\Polk" "Hsap\POLI, Hsap\ESCO2, Hsap\POLK, Hsap\POLH, Hsap\ESCO1" viable FBgn0266324 CR44989 - http://flybase.org/reports/FBgn0266324 non_protein_coding_gene - - - CR44989 - CR44989 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002322 l(3)86Fa lethal (3) 86Fa http://flybase.org/reports/FBgn0002322 - gene - - - "l(3)ck1, l(3)86Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,body color defective" "wing,adult cuticle" FBgn0011324 l(3)j2B1 lethal (3) j2B1 http://flybase.org/reports/FBgn0011324 - gene - - - l(3)j2B1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031766 CG9117 - http://flybase.org/reports/FBgn0031766 protein_coding_gene - - - CG9117 IPR001279:Metallo-beta-lactamase CG9117 11-Aug-17 DroID_v2017_08 Drer\mblac1 - "Cele\swip-10, Cele\C25D7.5, Cele\C23H3.9, Cele\B0432.9, Cele\C03F11.2" Xtro\mblac1 Mmus\Mblac1 Hsap\MBLAC1 "viable,fertile" FBgn0005085 fs(2)OW809 female sterile (2) OW809 http://flybase.org/reports/FBgn0005085 - gene - - - fs(2)OW809 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040614 CG12882 - http://flybase.org/reports/FBgn0040614 protein_coding_gene - - - CG12882 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027973 l(3)S141110 lethal (3) S141110 http://flybase.org/reports/FBgn0027973 gene - - - "1411/10, l(3)S141110" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025832 Fen1 Flap endonuclease 1 http://flybase.org/reports/FBgn0025832 - protein_coding_gene "nuclease activity ; GO:0004518 | inferred from electronic annotation with InterPro:IPR006084, InterPro:IPR006085, InterPro:IPR006086 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003583, InterPro:IPR008918, InterPro:IPR020045 endonuclease activity ; GO:0004519 | inferred from sequence or structural similarity" "DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR006084, InterPro:IPR006085 neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "DmFEN-1, EG:EG0003.3, CG8648, FEN1, Fen1, fen1" "IPR006085:XPG N-terminal, IPR006086:XPG-I domain, IPR008918:Helix-hairpin-helix motif, class 2, IPR019974:XPG conserved site, IPR020045:5'-3' exonuclease, C-terminal domain, IPR023426:Flap endonuclease 1, IPR006084:XPG/Rad2 endonuclease, IPR029060:PIN domain-like" CG8648 11-Aug-17 DroID_v2017_08 "Drer\zgc:110269, Drer\fen1" Scer\RAD27 Cele\crn-1 "Xtro\fen1, Xtro\gen1" "Mmus\Fen1, Mmus\Gen1" "Hsap\GEN1, Hsap\FEN1" "neuroanatomy defective,lethal,viable,visible" "neuroblast,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0035545 CG12607 - http://flybase.org/reports/FBgn0035545 protein_coding_gene - - - "BcDNA:RE67729, CG12607" - CG12607 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065554 l(2)SH1017 lethal (2) SH1017 http://flybase.org/reports/FBgn0065554 gene - - - "l(2)SH1017, l(2)SH2 1017" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037340 CG14671 - http://flybase.org/reports/FBgn0037340 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN001592797 - extrinsic component of endoplasmic reticulum membrane ; GO:0042406 | inferred from biological aspect of ancestor with PANTHER:PTN001592797 CG14671 - CG14671 11-Aug-17 DroID_v2017_08 Drer\ccdc115 Scer\VMA22 - - Mmus\Ccdc115 Hsap\CCDC115 FBgn0039644 CG11897 - http://flybase.org/reports/FBgn0039644 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN002384094 CG11897 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG11897 11-Aug-17 DroID_v2017_08 "Drer\abcc12, Drer\cftr, Drer\abcc3, Drer\abcc2, Drer\abcc6a, Drer\abcc9, Drer\abcc6b.2, Drer\abcc4, Drer\abcc5, Drer\abcc1, Drer\LOC100329706, Drer\abcc13, Drer\abcc8, Drer\abcc10" "Scer\YBT1, Scer\VMR1, Scer\YCF1, Scer\BPT1, Scer\NFT1, Scer\YKR104W, Scer\YOR1" "Cele\mrp-2, Cele\mrp-4, Cele\mrp-7, Cele\mrp-6, Cele\mrp-5, Cele\mrp-1, Cele\mrp-8, Cele\mrp-3" "Xtro\abcc6, Xtro\abcc1, Xtro\abcc3, Xtro\abcc10, Xtro\cftr, Xtro\abcc4" "Mmus\Abcc10, Mmus\Cftr, Mmus\Abcc9, Mmus\Abcc2, Mmus\Abcc1, Mmus\Abcc4, Mmus\Abcc12, Mmus\Abcc6, Mmus\Abcc8, Mmus\Abcc5, Mmus\Abcc3" "Hsap\ABCC5, Hsap\ABCC2, Hsap\ABCC11, Hsap\ABCC9, Hsap\ABCC1, Hsap\ABCC10, Hsap\ABCC12, Hsap\ABCC3, Hsap\ABCC4, Hsap\ABCC6, Hsap\ABCC8, Hsap\CFTR" viable DRSC26545 K 0.177360207 -0.207663781 -0.058802605 0.034238749 -0.691097197 2.061695079 FBgn0053922 CG33922 - http://flybase.org/reports/FBgn0053922 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33922 IPR010512:Protein of unknown function DUF1091 CG33922 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0033728 Cpr49Ae Cuticular protein 49Ae http://flybase.org/reports/FBgn0033728 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG8505, Cpr49Ae, DmelCpr49Ae" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8505 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - "visible,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum FBgn0004391 shtd shattered http://flybase.org/reports/FBgn0004391 FBgn0030639 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred by curator from GO:0005680 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from mutant phenotype anaphase-promoting complex ; GO:0005680 | inferred from genetic interaction with fzr anaphase-promoting complex ; GO:0005680 | traceable author statement "CG9198, shtd, Apc1, Shtd, APC1, SHTD" IPR024990:Anaphase-promoting complex subunit 1 CG9198 11-Aug-17 DroID_v2017_08 Drer\anapc1 Scer\APC1 "Cele\mat-2, Cele\apc-17" Xtro\anapc1 Mmus\Anapc1 Hsap\ANAPC1 "lethal - all die before end of pupal stage,some die during pupal stage,visible,mitotic cell cycle defective,increased cell death,lethal,neuroanatomy defective,viable" "eye,photoreceptor cell,mitotic cell cycle,eye disc,ommatidium,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0085325 CG34296 - http://flybase.org/reports/FBgn0085325 protein_coding_gene - - - CG34296 - CG34296 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065897 l(2)SH0206 lethal (2) SH0206 http://flybase.org/reports/FBgn0065897 gene - - - "l(2)SH0206, l(2)SH2 0206" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266041 CR44806 - http://flybase.org/reports/FBgn0266041 non_protein_coding_gene - - - CR44806 - CR44806 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001419 l(1)6Dc lethal (1) 6Dc http://flybase.org/reports/FBgn0001419 - gene - - - "EM25, l(1)EM25, l(1)EA42, l(1)6Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060300 nullo::Dvir\nullo nullo::Dvir\nullo http://flybase.org/reports/FBgn0060300 engineered_fusion_gene - - - nullo::Dvir\nullo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000134 Ars-region12 Autonomous replicating sequence region 12 http://flybase.org/reports/FBgn0000134 - region - - - "Dm665, Ars-region12, Ars12" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029181 E(Khc)ek6 E(Khc)ek6 http://flybase.org/reports/FBgn0029181 gene - - - E(Khc)ek6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024612 olf534 olfactory 534 http://flybase.org/reports/FBgn0024612 - gene - - - olf534 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005530 l(2)52ACg lethal (2) 52ACg http://flybase.org/reports/FBgn0005530 - gene - - - l(2)52ACg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029084 gom gomdanji http://flybase.org/reports/FBgn0029084 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from biological aspect of ancestor with PANTHER:PTN001474635 "CG6727, gom" IPR031973:Deltamethrin resistance protein prag01 CG6727 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0002503 l(3)SG63 lethal (3) SG63 http://flybase.org/reports/FBgn0002503 - gene - - - l(3)SG63 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0038005 Cyp313a5 Cyp313a5 http://flybase.org/reports/FBgn0038005 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "313a5, CG15807, Cyp313a5, CYP313a5" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG15807 11-Aug-17 DroID_v2017_08 "Drer\cyp4v7, Drer\cyp46a1.4, Drer\cyp4f3, Drer\zgc:123299, Drer\cyp19a1b, Drer\cyp4v8, Drer\cyp26c1, Drer\cyp26a1, Drer\cyp19a1a, Drer\cyp4t8, Drer\cyp46a1.3, Drer\cyp20a1, Drer\cyp46a1.1, Drer\cyp46a1.2, Drer\LOC100329425, Drer\cyp26b1" "Scer\ERG5, Scer\DIT2, Scer\ERG11" "Cele\cyp-29A4, Cele\cyp-29A3" "Xtro\cyp4f2, Xtro\cyp26b1, Xtro\cyp4f22, Xtro\cyp20a1, Xtro\cyp4v2, Xtro\cyp4b1, Xtro\cyp4b1.2, Xtro\cyp26a1, Xtro\LOC100488227, Xtro\mgc108213, Xtro\LOC100487918, Xtro\cyp26c1, Xtro\cyp19a1" "Mmus\Cyp4a14, Mmus\Cyp4a12a, Mmus\Cyp4f15, Mmus\Cyp4a10, Mmus\Cyp26b1, Mmus\Cyp19a1, Mmus\Cyp4f14, Mmus\Cyp4a32, Mmus\Cyp4a12b, Mmus\Cyp4f37, Mmus\Cyp4f17, Mmus\Cyp46a1, Mmus\Cyp4f16, Mmus\Cyp4f39, Mmus\Cyp4b1, Mmus\Cyp4f13, Mmus\Cyp4x1, Mmus\Cyp20a1, Mmus\Cyp4f18, Mmus\Cyp4v3, Mmus\Cyp26c1, Mmus\Cyp26a1, Mmus\Cyp4a31, Mmus\Cyp4f40" "Hsap\CYP4B1, Hsap\CYP4F22, Hsap\CYP46A1, Hsap\CYP4V2, Hsap\CYP4A22, Hsap\CYP4F11, Hsap\CYP4F12, Hsap\CYP26C1, Hsap\CYP26B1, Hsap\CYP4F3, Hsap\CYP4Z1, Hsap\CYP19A1, Hsap\CYP20A1, Hsap\CYP4A11, Hsap\CYP4F2, Hsap\CYP4X1, Hsap\CYP26A1" viable FBgn0002870 mu mussed http://flybase.org/reports/FBgn0002870 - gene - - - mu - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "adult thorax,dorsal,wing" FBgn0035626 lin-28 lin-28 http://flybase.org/reports/FBgn0035626 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002059 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 mRNA binding ; GO:0003729 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002059 oogenesis ; GO:0048477 | inferred from mutant phenotype symmetric stem cell division ; GO:0098724 | inferred from mutant phenotype positive regulation of stem cell proliferation ; GO:2000648 | inferred from mutant phenotype negative regulation of pre-miRNA processing ; GO:2000632 | inferred from mutant phenotype positive regulation of insulin receptor signaling pathway ; GO:0046628 | inferred from mutant phenotype inferred from genetic interaction with InR" - "CG17334, EP(3)0915, BcDNA:RE05342, lin-28, lin28" "IPR001878:Zinc finger, CCHC-type, IPR002059:Cold-shock protein, DNA-binding, IPR011129:Cold shock domain, IPR012340:Nucleic acid-binding, OB-fold" CG17334 11-Aug-17 DroID_v2017_08 "Drer\lin28a, Drer\si:ch1073-284b18.2, Drer\csdc2a, Drer\ybx1" - "Cele\F54G2.2, Cele\lin-28, Cele\cey-1" "Xtro\lin28b, Xtro\ybx1, Xtro\ybx2, Xtro\carhsp1, Xtro\lin28a, Xtro\ybx3" "Mmus\Ybx3, Mmus\Ybx2, Mmus\Csdc2, Mmus\Lin28a, Mmus\Ybx1, Mmus\Carhsp1, Mmus\Lin28b" "Hsap\YBX1, Hsap\LIN28A, Hsap\LIN28B, Hsap\CARHSP1, Hsap\YBX3, Hsap\CSDC2, Hsap\YBX2" embryonic stage " embryonic stage , larval stage | first instar , pupal stage " DRSC10261 EK -0.863058748 -1.142396815 -2.337710006 0.94765551 2.245989086 1.911352244 FBgn0035173 CG13907 - http://flybase.org/reports/FBgn0035173 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG13907 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG13907 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-246g23.4, Drer\slc16a13, Drer\LOC103911912, Drer\slc16a1a, Drer\slc16a12b, Drer\slc16a9b, Drer\si:ch211-234h8.7, Drer\slc16a6b, Drer\slc16a6a, Drer\slc16a5a, Drer\slc16a12a, Drer\slc16a7, Drer\slc16a5b, Drer\zgc:114041, Drer\slc16a9a, Drer\slc16a4" "Scer\MCH5, Scer\MCH4, Scer\ATG22, Scer\ESBP6, Scer\MCH2" "Cele\mct-3, Cele\mct-4" "Xtro\slc16a2, Xtro\slc16a7, Xtro\slc16a13, Xtro\slc16a14, Xtro\slc16a12, Xtro\slc16a5, Xtro\slc16a9, Xtro\slc16a3" "Mmus\Slc16a6, Mmus\Slc16a5, Mmus\Slc16a14, Mmus\Slc16a13, Mmus\Slc16a4, Mmus\Slc16a11, Mmus\Slc16a9, Mmus\Slc16a12" "Hsap\SLC16A6, Hsap\SLC16A10, Hsap\SLC16A14, Hsap\SLC16A8, Hsap\SLC16A11, Hsap\SLC16A12, Hsap\SLC16A1, Hsap\SLC16A4, Hsap\SLC16A5, Hsap\SLC16A13, Hsap\SLC16A9" FBgn0259997 CG41073 - http://flybase.org/reports/FBgn0259997 protein_coding_gene - - - "anon-38C.19, CG41073, CG40171, 38C.19" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034946 CG3065 - http://flybase.org/reports/FBgn0034946 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with HGNC:11209 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:11209 CG3065 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3065 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-117k10.3, Drer\klf15, Drer\egr3, Drer\zgc:113336" "Scer\SWI5, Scer\RPH1, Scer\USV1, Scer\ACE2, Scer\RGM1" Cele\Y55F3AM.14 "Xtro\klf15, Xtro\klf15.2" "Mmus\Klf17, Mmus\Zfp352, Mmus\Zfp128, Mmus\Klf15, Mmus\Egr3" "Hsap\KLF15, Hsap\EGR3, Hsap\ZNF8, Hsap\ZNF461" "viable,fertile" FBgn0026354 Su(SuRaf1)19-2 Su(SuRaf1)19-2 http://flybase.org/reports/FBgn0026354 - gene - - - "Su[Su(Raf)1]19-2, Su(SuRaf1)19-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001509 l(1)10Fc lethal (1) 10Fc http://flybase.org/reports/FBgn0001509 - gene - - - l(1)10Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038638 CG7702 - http://flybase.org/reports/FBgn0038638 protein_coding_gene - - - "CT23351, CG7702, 7702" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG7702 11-Aug-17 DroID_v2017_08 "Drer\tpbgl, Drer\LOC100537897, Drer\waif2, Drer\tpbgb" - "Cele\iglr-3, Cele\lron-7" - "Mmus\Tpbg, Mmus\Tpbgl" "Hsap\TPBGL, Hsap\TPBG" "viable,fertile" FBgn0027564 CG3149 - http://flybase.org/reports/FBgn0027564 - protein_coding_gene lipid transporter activity ; GO:0005319 | inferred from electronic annotation with InterPro:IPR007594 glycolipid translocation ; GO:0034203 | inferred from biological aspect of ancestor with PANTHER:PTN000319164 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007594 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000319164 "BcDNA:GH08388, CG3149" IPR007594:RFT1 CG3149 11-Aug-17 DroID_v2017_08 Drer\rft1 Scer\RFT1 Cele\ZK180.3 Xtro\rft1 Mmus\Rft1 Hsap\RFT1 FBgn0061141 l(3)S000624c lethal (3) S000624c http://flybase.org/reports/FBgn0061141 gene - - - l(3)S000624c - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000286 Cf2 Chorion factor 2 http://flybase.org/reports/FBgn0000286 FBgn0062475 protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CF2, CG11924, cf2, CF2.5, BcDNA:GM09668, Cf2" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11924 11-Aug-17 DroID_v2017_08 "Drer\LOC103911016, Drer\si:dkey-262g12.3, Drer\znf973, Drer\LOC101883230, Drer\si:dkey-261j4.5, Drer\im:7141269, Drer\si:ch211-40k21.9, Drer\LOC101883594, Drer\LOC100537317, Drer\znf1023, Drer\drl, Drer\wu:fe17e08, Drer\si:dkey-261j4.3, Drer\zgc:165514, Drer\si:dkey-228b2.6, Drer\LOC560148, Drer\si:ch211-241b2.4, Drer\LOC108179164, Drer\zbtb24, Drer\LOC100333031, Drer\si:ch211-155e24.3, Drer\arl14ep, Drer\si:ch73-299h12.9, Drer\si:ch211-276c2.4, Drer\LOC100330167, Drer\si:ch211-198a12.6, Drer\zgc:171673, Drer\thap3, Drer\si:ch73-40a17.4, Drer\si:dkey-261j4.4, Drer\si:ch211-222k6.2, Drer\si:dkey-201g16.1, Drer\zgc:112998, Drer\si:ch73-389k6.1, Drer\zgc:113364, Drer\si:dkey-34m19.3, Drer\LOC103909987, Drer\thap1, Drer\LOC100538142, Drer\LOC799968" "Scer\YPR015C, Scer\AZF1, Scer\CMR3" "Cele\egrh-3, Cele\Y56A3A.28, Cele\blmp-1, Cele\che-1, Cele\hbl-1, Cele\lin-29, Cele\scrt-1" "Xtro\prdm1, Xtro\thap1, Xtro\thap5" "Mmus\Thap3, Mmus\Zfp853, Mmus\Zfp110, Mmus\Thap1, Mmus\Zbtb24, Mmus\Zfp637, Mmus\Thap2" "Hsap\THAP5, Hsap\THAP2, Hsap\THAP3, Hsap\THAP8, Hsap\ZNF32, Hsap\ZNF853, Hsap\THAP1, Hsap\ZNF274" " oogenesis stage && adult stage | female , adult stage && oogenesis stage , adult stage | male , embryonic stage , spermatogenesis && adult stage , embryonic stage -- adult stage , pupal stage " " ovary

, follicle cell

, testis

, egg chamber

" adult stage && oogenesis stage follicle cell

"viable,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,lethal,visible,flightless,jumping defective,flight defective" "indirect flight muscle,myosin filament,dorsal appendage,non-rescuable maternal effect,denticle belt,embryonic/first instar larval cuticle,egg chamber,follicle cell,trichogen cell,mesothoracic tergum,mesothoracic extracoxal depressor muscle 66,Z disc,M band" FBgn0263966 BG02395 - http://flybase.org/reports/FBgn0263966 gene - - - BG02395 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective" FBgn0001428 stout strung out http://flybase.org/reports/FBgn0001428 - gene - - - "JNXL1, jnL1, l(1)jnL1, l(1)6Ee, stout" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,visible,dominant" "hypostomal sclerite,dorsal bridge,mouth hooks,metathoracic ventral denticle belt,arista,wing,macrochaeta" FBgn0002409 l(3)99Dj lethal (3) 99Dj http://flybase.org/reports/FBgn0002409 - gene - - - l(3)99Dj - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266504 s-332 - http://flybase.org/reports/FBgn0266504 gene - - - s-332 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034844 CG9861 - http://flybase.org/reports/FBgn0034844 protein_coding_gene - - - CG9861 "IPR031936:Domain of unknown function DUF4771, IPR031935:Domain of unknown function DUF4770" CG9861 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC04576 E -0.352295782 0.217012298 3.690707226 -0.288847633 0.793603246 -0.814203882 FBgn0020055 E(w[a])757 E(w[a])757 http://flybase.org/reports/FBgn0020055 - gene - - - "E757, E(w[a])757" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0263625 CR43634 - http://flybase.org/reports/FBgn0263625 non_protein_coding_gene - - - "CR43634, lincRNA.851" - CR43634 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086409 dbb doublebubble http://flybase.org/reports/FBgn0086409 gene - - - dbb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035695 CG10226 - http://flybase.org/reports/FBgn0035695 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 xenobiotic-transporting ATPase activity ; GO:0008559 | inferred from sequence or structural similarity with UniProtKB:Q00748 efflux transmembrane transporter activity ; GO:0015562 | inferred from sequence or structural similarity with UniProtKB:Q00748" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 response to toxic substance ; GO:0009636 | inferred from expression pattern renal tubular secretion ; GO:0097254 | inferred from expression pattern xenobiotic transport ; GO:0042908 | inferred from sequence or structural similarity with UniProtKB:Q00748 ATP-binding cassette (ABC) transporter complex ; GO:0043190 | inferred from sequence or structural similarity with UniProtKB:Q00748 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q00748 "CG10226, AMT" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG10226 11-Aug-17 DroID_v2017_08 "Drer\abcb11a, Drer\abcb9, Drer\abcb10, Drer\abcb4, Drer\abcb5, Drer\abcb11b, Drer\abcb8, Drer\abcb3l1" Scer\STE6 "Cele\haf-9, Cele\pgp-3, Cele\pgp-4, Cele\haf-7, Cele\pgp-14, Cele\pgp-8, Cele\pgp-6, Cele\pgp-9, Cele\pgp-5, Cele\pgp-10, Cele\haf-4, Cele\haf-2, Cele\haf-1, Cele\haf-6, Cele\pgp-13, Cele\haf-8, Cele\pgp-1, Cele\haf-3, Cele\pgp-7, Cele\pgp-11, Cele\pgp-12, Cele\pgp-2" "Xtro\abcb8, Xtro\LOC100494740" "Mmus\Abcb1b, Mmus\Abcb11, Mmus\Abcb8, Mmus\Abcb10, Mmus\Abcb1a, Mmus\Abcb9, Mmus\Abcb4, Mmus\Abcb5" "Hsap\ABCB10, Hsap\ABCB8, Hsap\ABCB5, Hsap\ABCB1, Hsap\ABCB4, Hsap\ABCB11" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0051038 CG31038 - http://flybase.org/reports/FBgn0051038 protein_coding_gene - - - "CG7854, CG15512, CG31038" - CG31038 11-Aug-17 DroID_v2017_08 "Drer\fam89a, Drer\fam89b" - - - "Mmus\Fam89a, Mmus\Fam89b" "Hsap\FAM89A, Hsap\FAM89B" "viable,fertile" FBgn0040743 CG15919 - http://flybase.org/reports/FBgn0040743 protein_coding_gene - - - CG15919 IPR032134:Protein of unknown function DUF4816 CG15919 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027513 ana2 anastral spindle 2 http://flybase.org/reports/FBgn0027513 - protein_coding_gene - centriole replication ; GO:0007099 | inferred from direct assay establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype centriole assembly ; GO:0098534 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype centriole-centriole cohesion ; GO:0010457 | inferred from direct assay microtubule anchoring at centrosome ; GO:0034454 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay "BcDNA:LD22033, Ana2, Ana-2, CG8262, ana2" - CG8262 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,meiotic cell cycle defective,viable" "embryonic/larval neuroblast,supernumerary,mushroom body neuroblast,astral microtubule,type I neuroblast,somatic clone,type II neuroblast,secondary neuroblast,centriolemat.‘±Tub67C.THsimVP16,centriole,spermatocyte" FBgn0065191 l(2)SH2329 lethal (2) SH2329 http://flybase.org/reports/FBgn0065191 gene - - - "l(2)SH2329, l(2)SH2 2329" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005533 RpS17 Ribosomal protein S17 http://flybase.org/reports/FBgn0005533 "FBgn0002217, FBgn0002615, FBgn0025290, FBgn0064883" protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001210, InterPro:IPR018273 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000077142 cytoplasmic translation ; GO:0002181 | traceable author statement" cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "M(3)i(55), CG3922, M(3)RpS17, RPS17, M(3)67C, M(3)i[55], D9, M(3)i, M(3)67, M(3L)i[55], M(3L)i, rpS17, l(3)dtOA4, l(3)67BDo, anon-EST:Posey48, M(3)q, M(3)S33, BcDNA:RE44119, RpS17, Rps17, M, Minute, Rp S17, RS17_DROME, minute" "IPR018273:Ribosomal protein S17e, conserved site, IPR001210:Ribosomal protein S17e" CG3922 11-Aug-17 DroID_v2017_08 "Drer\rps17, Drer\zgc:114188" "Scer\RPS17A, Scer\RPS17B" Cele\rps-17 Xtro\rps17 Mmus\Rps17 Hsap\RPS17 "Minute,developmental rate defective,partially lethal - majority live,female sterile,dominant,visible,lethal,recessive,cell lethalcell lethal,somatic clone,size defective" "macrochaeta,adult heart" DRSC11271 EK -0.391006664 -1.21262834 1.241025078 -3.162834602 -0.87455409 2.752812484 FBgn0262971 CR43282 - http://flybase.org/reports/FBgn0262971 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "CR43282, hpRNA1" - CR43282 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085273 CG34244 - http://flybase.org/reports/FBgn0085273 protein_coding_gene - - - CG34244 IPR002350:Kazal domain CG34244 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262360 CG43058 - http://flybase.org/reports/FBgn0262360 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000548413 negative regulation of protein sumoylation ; GO:0033234 | inferred from biological aspect of ancestor with PANTHER:PTN001495439 protein ubiquitination ; GO:0016567 | inferred from biological aspect of ancestor with PANTHER:PTN000548413 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000548413 SUMO-targeted ubiquitin ligase complex ; GO:0033768 | inferred from biological aspect of ancestor with PANTHER:PTN001495439 CG43058 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR017907:Zinc finger, RING-type, conserved site" CG43058 11-Aug-17 DroID_v2017_08 "Drer\trim35-30, Drer\si:ch1073-324l1.1, Drer\si:ch73-106l15.2, Drer\trim35-33, Drer\trim35-20, Drer\si:ch211-175l6.2, Drer\trim35-29, Drer\trim35-34, Drer\trim35-13, Drer\trim35-10, Drer\si:ch73-166o21.1, Drer\si:ch211-12p12.2, Drer\trim35-19, Drer\trim35-35, Drer\LOC100536643, Drer\trim35-31, Drer\ftr70, Drer\trim35-28, Drer\rnf4, Drer\trim35-24, Drer\trim35-12, Drer\trim35-23, Drer\si:ch73-106l15.3, Drer\trim35-14, Drer\trim35-1, Drer\trim35-25, Drer\rnf222, Drer\trim35-3, Drer\trim35-7, Drer\trim35-9" Scer\SLX8 "Cele\T01G5.7, Cele\Y38C1AA.6, Cele\C28G1.6" "Xtro\trim69.2, Xtro\rnf4" "Mmus\Rnf222, Mmus\Rnf4, Mmus\Trim35, Mmus\Trim7, Mmus\Trim10, Mmus\Trim26" "Hsap\RNF4, Hsap\TRIM10, Hsap\TRIM7, Hsap\TRIM35, Hsap\TRIM26, Hsap\RNF222" FBgn0085731 CG42229 - http://flybase.org/reports/FBgn0085731 protein_coding_gene - - - CG42229 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011933 tRNA:Asn-GTT-1-4 transfer RNA:Asparagine-GTT 1-4 http://flybase.org/reports/FBgn0011933 "FBgn0003759, FBgn0050307, FBgn0050518, FBgn0060132" tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "asn-tRNA, AE002769.trna6-AsnGTT, tRNA:N:GTT:AE002769-b, tRNA:asn5:42Ac, CR30307, CR30518, chr2R.trna97-AsnGTT, tRNA-Asn-GTT-1-4, tRNA:Asn-GTT-1-4, tRNA:N5:42Ac, AAC" - CR30518 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051106 CG31106 - http://flybase.org/reports/FBgn0051106 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 "CG31106, CG13655" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG31106 11-Aug-17 DroID_v2017_08 "Drer\sv2ba, Drer\oatx, Drer\svopb, Drer\slc22a7b.1, Drer\sv2, Drer\sv2bb, Drer\slc22a5, Drer\LOC100334012, Drer\sv2c, Drer\slc22a6l, Drer\sv2a, Drer\zgc:175176, Drer\svopa, Drer\slc22a13, Drer\zmp:0000001102, Drer\LOC101884074, Drer\slc22a21, Drer\slc22a7b.2, Drer\svopl, Drer\slc22a7b.3" "Scer\TPO1, Scer\HXT9, Scer\QDR1, Scer\QDR3, Scer\TPO2, Scer\TPO3, Scer\AQR1, Scer\QDR2, Scer\DTR1, Scer\FLR1, Scer\YHK8" "Cele\svop-1, Cele\ZK892.3, Cele\C46C2.2, Cele\Y57G11C.23, Cele\C53B4.1" "Xtro\slc22a6, Xtro\sv2b" "Mmus\Slc22a28, Mmus\Svop, Mmus\Slc22a22, Mmus\Svopl, Mmus\Slc22a29, Mmus\Sv2a, Mmus\Slc22a20, Mmus\Slc22a14, Mmus\Slc22a16, Mmus\Slc22a23, Mmus\Slc22a26, Mmus\Slc22a27, Mmus\Slc22a8, Mmus\Slc22a6, Mmus\Sv2b, Mmus\Slc22a4, Mmus\Sv2c, Mmus\Slc22a2, Mmus\Slc22a30, Mmus\Slc22a7, Mmus\Slc22a19" "Hsap\SLC22A24, Hsap\SLC22A1, Hsap\SV2C, Hsap\SLC22A11, Hsap\SLC22A9, Hsap\SLC22A2, Hsap\SLC22A25, Hsap\SLC22A7, Hsap\SLC22A10, Hsap\SV2B, Hsap\SVOPL, Hsap\SLC22A8, Hsap\SVOP, Hsap\SLC22A12, Hsap\SLC22A23, Hsap\SLC22A6, Hsap\SV2A" viable FBgn0082590 l(2)NC309 lethal (2) NC309 http://flybase.org/reports/FBgn0082590 gene - - - "NC309, l(2)NC309" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266108 mei-86 meiotic 86 http://flybase.org/reports/FBgn0266108 gene - female meiotic division ; GO:0007143 | inferred from mutant phenotype - mei-86 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,meiotic cell cycle defective,female" FBgn0005679 mcd2 muscle cell death 2 http://flybase.org/reports/FBgn0005679 - gene - - - "mcd-2, mcd2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "muscle 18a,maternal effect,muscle 18b" FBgn0262142 CR42868 - http://flybase.org/reports/FBgn0262142 non_protein_coding_gene - - - "CG42868, CR42868" - CR42868 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060945 l(3)S038305 lethal (3) S038305 http://flybase.org/reports/FBgn0060945 gene - - - "0383/05, l(3)S038305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal" FBgn0001356 l(1)1EFe lethal (1) 1EFe http://flybase.org/reports/FBgn0001356 - gene - - - "l(1)BA5, l(1)1EFe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030832 CG10597 - http://flybase.org/reports/FBgn0030832 protein_coding_gene - - - CG10597 - CG10597 11-Aug-17 DroID_v2017_08 Drer\prnpa - - - - - viable FBgn0050480 CG30480 - http://flybase.org/reports/FBgn0050480 protein_coding_gene - - - "CG18373, CG30480" - CG30480 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0040796 CG13064 - http://flybase.org/reports/FBgn0040796 protein_coding_gene - - - CG13064 - CG13064 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065264 l(2)SH2077 lethal (2) SH2077 http://flybase.org/reports/FBgn0065264 gene - - - "l(2)SH2077, l(2)SH2 2077" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034323 CG18537 - http://flybase.org/reports/FBgn0034323 protein_coding_gene - - - CG18537 IPR010512:Protein of unknown function DUF1091 CG18537 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266887 CR45348 - http://flybase.org/reports/FBgn0266887 non_protein_coding_gene - - - CR45348 - CR45348 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002435 l(3)KX305 lethal (3) KX305 http://flybase.org/reports/FBgn0002435 - gene - - - l(3)KX305 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002143 l(2)K333 lethal (2) K333 http://flybase.org/reports/FBgn0002143 - gene - - - l(2)K333 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262422 mir-1011 mir-1011 stem loop http://flybase.org/reports/FBgn0262422 miRNA_gene - - - "mir-1011, dme-mir-1011, CR42974, miR-1011" - CR42974 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030208 PPP4R2r Protein phosphatase 4 regulatory subunit 2-related protein http://flybase.org/reports/FBgn0030208 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from electronic annotation with InterPro:IPR015267 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype "protein phosphatase 4 complex ; GO:0030289 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from physical interaction with Cenp-C" "R2, CG2890, PPP4R2, BcDNA:LD29930, PPP4R2r, PP4R2, PP4R, Ppp4R2, PP4R2r" IPR015267:Protein phosphatase 4 core regulatory subunit R2 CG2890 11-Aug-17 DroID_v2017_08 "Drer\ppp4r2b, Drer\ppp4r2a" Scer\PSY4 "Cele\H39E23.3, Cele\ppfr-2" Xtro\ppp4r2 Mmus\Ppp4r2 Hsap\PPP4R2 "decreased cell number,lethal,neuroanatomy defective,viable" "neuroblast,ganglion mother cell" FBgn0261349 Mst36Fb Male-specific transcript 36Fb http://flybase.org/reports/FBgn0261349 protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "mst36Fb, CG31791, CG15165, Mst36Fb, CG42626" - CG42626 11-Aug-17 DroID_v2017_08 - - - - - - "male semi-fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0032354 CG4788 - http://flybase.org/reports/FBgn0032354 protein_coding_gene - - - CG4788 - CG4788 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040214 fs(?)BL54 fs(?)BL54 http://flybase.org/reports/FBgn0040214 gene - - - fs(?)BL54 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0266878 CR45339 - http://flybase.org/reports/FBgn0266878 non_protein_coding_gene - - - CR45339 - CR45339 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000214 brc brachymacrochaetae http://flybase.org/reports/FBgn0000214 - gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - "DCE-12, C93, l(1)1Db, brc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,polyphasic" "macrochaeta & thorax,dorsocentral bristle,scutellar bristle,mesothoracic bristle,macrochaeta" FBgn0039873 Smvt Sodium-dependent multivitamin transporter http://flybase.org/reports/FBgn0039873 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "SMVT, smvt, CG2191, Smvt, dSLC5A5" IPR001734:Sodium/solute symporter CG2191 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-9d4.5, Drer\slc5a12, Drer\slc5a6a, Drer\slc5a6b, Drer\LOC568338, Drer\slc5a8l, Drer\slc5a11, Drer\slc5a2, Drer\slc5a5, Drer\slc5a8, Drer\slc5a3a, Drer\slc5a9, Drer\slc5a1" Scer\DUR3 "Cele\F52H2.4, Cele\ZK822.5" "Xtro\slc5a2, Xtro\slc5a1.1, Xtro\slc5a5, Xtro\slc5a8, Xtro\slc5a12, Xtro\slc5a9, Xtro\slc5a11" "Mmus\Slc5a1, Mmus\Slc5a9, Mmus\Slc5a5, Mmus\Slc5a2, Mmus\Slc5a10, Mmus\Slc5a4a, Mmus\Slc5a4b, Mmus\Slc5a8, Mmus\Gm5134, Mmus\Slc5a12, Mmus\Slc5a3, Mmus\Slc5a11, Mmus\Slc5a6" "Hsap\SLC5A10, Hsap\SLC5A1, Hsap\SLC5A3, Hsap\SLC5A12, Hsap\SLC5A6, Hsap\SLC5A5, Hsap\SLC5A2, Hsap\SLC5A11, Hsap\SLC5A4, Hsap\SLC5A8, Hsap\SLC5A9" "visible,partially lethal - majority die,some die during pupal stage,viable,fertile" trichogen cell FBgn0003061 anon-Pen57BC anon-Pen57BC http://flybase.org/reports/FBgn0003061 - gene - - - "GCR-27, pen57BC, Pen57BC, GCR27, anon-Pen57BC" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032763 CG17568 - http://flybase.org/reports/FBgn0032763 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG17568 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG17568 11-Aug-17 DroID_v2017_08 "Drer\znf865, Drer\LOC101883087, Drer\znfl2a" - "Cele\fezf-1, Cele\Y55F3AM.14, Cele\eor-1, Cele\ztf-23, Cele\pag-3" - "Mmus\Zfp865, Mmus\Zfp212, Mmus\Zfp667" "Hsap\ZNF667, Hsap\ZNF865, Hsap\ZNF212, Hsap\ZNF783, Hsap\ZNF763, Hsap\ZNF671, Hsap\ZNF662" "viable,fertile" FBgn0085644 CR41423 - http://flybase.org/reports/FBgn0085644 pseudogene_attribute - - - "CG41423, CR41423" - CR41423 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034504 CG8929 - http://flybase.org/reports/FBgn0034504 protein_coding_gene - - - "anon-WO0118547.91, CG8929" "IPR022137:Protein of unknown function DUF3669, zinc finger protein" CG8929 11-Aug-17 DroID_v2017_08 - - - - Mmus\AU019823 "Hsap\C11orf57, Hsap\SRRM4" viable DRSC22847 EK -0.210513875 0.589169143 0.365611414 2.143688128 -0.38535577 -1.541576429 FBgn0027586 CG5867 - http://flybase.org/reports/FBgn0027586 - protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CT18390, BcDNA:GH05536, CG5867" IPR010562:Haemolymph juvenile hormone binding CG5867 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035607 CG4835 - http://flybase.org/reports/FBgn0035607 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG4835 IPR002557:Chitin binding domain CG4835 11-Aug-17 DroID_v2017_08 - - "Cele\C39D10.7, Cele\cpg-1, Cele\R02F2.4, Cele\cpg-2" - - - viable FBgn0028551 3Cy(2)2 3Cy(2)2 http://flybase.org/reports/FBgn0028551 gene - - - 3Cy(2)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0029853 CG3781 - http://flybase.org/reports/FBgn0029853 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from biological aspect of ancestor with PANTHER:PTN000328962 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:28853 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:28853 protein deubiquitination ; GO:0016579 | inferred from biological aspect of ancestor with PANTHER:PTN000328962 cellular_component ; GO:0005575 | no biological data available "CG3781, Q9W422, JosD2" IPR006155:Josephin domain CG3781 11-Aug-17 DroID_v2017_08 "Drer\josd2, Drer\josd1" - "Cele\josd-1, Cele\atx-3" "Xtro\josd1, Xtro\josd2" "Mmus\Josd2, Mmus\Josd1, Mmus\Gm10651" "Hsap\JOSD1, Hsap\JOSD2" "viable,locomotor behavior defective" FBgn0032024 CG14273 - http://flybase.org/reports/FBgn0032024 protein_coding_gene - - - CG14273 - CG14273 11-Aug-17 DroID_v2017_08 - - - - - - DRSC02377 E 1.246913382 1.435130563 1.758280927 0.158196672 -0.177995774 0.438144834 FBgn0061004 l(3)S026438 lethal (3) S026438 http://flybase.org/reports/FBgn0061004 gene - - - "0264/38, l(3)S026438" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036518 RhoGAP71E Rho GTPase activating protein at 71E http://flybase.org/reports/FBgn0036518 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from mutant phenotype GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with SGD:S000000957 Rho protein signal transduction ; GO:0007266 | inferred from sequence or structural similarity with SGD:S000000957 apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype apical part of cell ; GO:0045177 | inferred from direct assay "CG16980, CG7396, RhoGAP-71E1, l(3)j6B9, CG32149, BcDNA:LD07615, RhoGAP71E, RhoGap71E, rhogap71e, C- GAP" "IPR000198:Rho GTPase-activating protein domain, IPR008936:Rho GTPase activation protein, IPR015943:WD40/YVTN repeat-like-containing domain" CG32149 11-Aug-17 DroID_v2017_08 "Drer\arhgap12b, Drer\tagapa, Drer\tagapb, Drer\arhgap20" - "Cele\2RSSE.1, Cele\rga-2" "Xtro\arhgap20, Xtro\tagap" "Mmus\Tagap1, Mmus\Gm1527, Mmus\Tagap, Mmus\1700006A11Rik, Mmus\Arhgap20" "Hsap\ARHGAP40, Hsap\TAGAP, Hsap\ARHGAP20" "lethal,recessive,neuroanatomy defective,somatic clone,viable" "mushroom body & neuron | somatic clone,adult mushroom body,somatic clone" DRSC10232 I 1.040665398 2.675912947 0.699027824 1.151873403 0.225028776 0.017226112 FBgn0085113 S53.1 S53.1 http://flybase.org/reports/FBgn0085113 gene - - - S53.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0035034 CG3565 - http://flybase.org/reports/FBgn0035034 protein_coding_gene - - - "anon-WO0140519.176, CG3565" IPR011992:EF-hand domain pair CG3565 11-Aug-17 DroID_v2017_08 "Drer\tesca, Drer\ppp3r1b, Drer\tescb, Drer\chp2, Drer\LOC100536377, Drer\ppp3r1a, Drer\efcab1, Drer\chp1" Scer\CNB1 - "Xtro\chp1, Xtro\ppp3r1, Xtro\cib1, Xtro\efcab1" "Mmus\Efcab1, Mmus\Chp2, Mmus\1700109H08Rik, Mmus\Guca1a, Mmus\Tesc, Mmus\Ppp3r2, Mmus\Cib1, Mmus\Cib4, Mmus\Chp1, Mmus\Ppp3r1, Mmus\Tescl" "Hsap\EFCAB1, Hsap\PPP3R2, Hsap\CIB1, Hsap\GUCA1A, Hsap\PPP3R1, Hsap\CHP2, Hsap\TESC, Hsap\CHP1, Hsap\CIB4" "viable,fertile" FBgn0027637 ms(1)10 male sterile (1) 10 http://flybase.org/reports/FBgn0027637 - gene - - - ms(1)10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile" FBgn0013575 l(3)82Fc lethal (3) 82Fc http://flybase.org/reports/FBgn0013575 - gene - - - l(3)82Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038083 CG5999 - http://flybase.org/reports/FBgn0038083 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG5999 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG5999 11-Aug-17 DroID_v2017_08 "Drer\ugt5d1, Drer\ugt5b3, Drer\ugt5g1, Drer\ugt2a6, Drer\ugt2a2, Drer\ugt2b5, Drer\ugt5g2, Drer\ugt5e1, Drer\ugt5f1, Drer\ugt2b3, Drer\ugt1b4, Drer\ugt5a1, Drer\ugt5a4, Drer\ugt5b6, Drer\ugt5b1, Drer\ugt1ab, Drer\ugt2a5, Drer\ugt5a5, Drer\ugt5c3, Drer\ugt1b2, Drer\ugt5c1, Drer\ugt1b7, Drer\ugt5b2, Drer\ugt2b1, Drer\ugt8, Drer\ugt1b3, Drer\zgc:172315, Drer\ugt5a2, Drer\ugt5c2, Drer\ugt1b5, Drer\ugt2b6" Scer\ATG26 "Cele\ugt-43, Cele\F10D2.8, Cele\ugt-58, Cele\ugt-55, Cele\ugt-18, Cele\ugt-1, Cele\ugt-2, Cele\K04A8.10, Cele\ugt-5, Cele\ugt-50, Cele\ugt-20, Cele\ugt-63, Cele\H23N18.4, Cele\ugt-48, Cele\ugt-42, Cele\ugt-44, Cele\C55H1.1, Cele\ugt-7, Cele\ugt-11, Cele\ugt-16, Cele\ugt-26, Cele\ugt-45, Cele\ugt-22, Cele\ugt-4, Cele\ugt-31, Cele\ugt-52, Cele\ugt-23, Cele\ugt-3, Cele\ugt-6, Cele\C23G10.6, Cele\ugt-13, Cele\ugt-39, Cele\ugt-25, Cele\ugt-35, Cele\ugt-21, Cele\ugt-9, Cele\ugt-24, Cele\ugt-56, Cele\ugt-49, Cele\ugt-10, Cele\ugt-17, Cele\C03A7.13, Cele\ugt-46, Cele\ugt-59, Cele\ugt-28, Cele\ugt-29, Cele\ugt-47, Cele\ugt-14, Cele\ugt-27, Cele\ugt-12, Cele\ugt-37, Cele\ugt-8, Cele\ugt-32, Cele\ugt-41, Cele\ugt-38, Cele\ugt-34, Cele\ugt-65, Cele\ugt-53, Cele\ugt-62, Cele\ugt-36, Cele\ugt-19, Cele\ugt-30, Cele\ugt-57, Cele\Y43D4A.2, Cele\ugt-60, Cele\ugt-15, Cele\ugt-54, Cele\ugt-40, Cele\ugt-33, Cele\ugt-61, Cele\C03A7.12, Cele\ugt-51" "Xtro\ugt8, Xtro\ugt1a6, Xtro\ugt2a1, Xtro\ugt3a2, Xtro\ugt2b4" "Mmus\Ugt1a5, Mmus\Ugt2b5, Mmus\Ugt2b37, Mmus\Ugt1a1, Mmus\Ugt1a9, Mmus\Ugt3a2, Mmus\Ugt8a, Mmus\Ugt1a6b, Mmus\Ugt2b34, Mmus\Ugt2a1, Mmus\Ugt2b36, Mmus\Ugt1a7c, Mmus\Ugt2a3, Mmus\Ugt2b38, Mmus\Ugt3a1, Mmus\Ugt2b35, Mmus\Ugt1a2, Mmus\Ugt2b1" "Hsap\UGT8, Hsap\UGT1A10, Hsap\UGT3A2, Hsap\UGT1A9, Hsap\UGT2B10, Hsap\UGT1A1, Hsap\UGT1A4, Hsap\UGT1A3, Hsap\UGT1A6, Hsap\UGT2A2, Hsap\UGT1A7, Hsap\UGT1A8, Hsap\UGT3A1, Hsap\UGT2B4, Hsap\UGT2A3, Hsap\UGT2B15, Hsap\UGT2B17, Hsap\UGT2B28, Hsap\UGT2B7, Hsap\UGT1A5, Hsap\UGT2B11" "lethal,viable" FBgn0085803 CR41550 - http://flybase.org/reports/FBgn0085803 rRNA_gene - - - CR41550 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038644 CG7710 - http://flybase.org/reports/FBgn0038644 protein_coding_gene - - - "BcDNA:LP06586, CG7710" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031378 CG15362 - http://flybase.org/reports/FBgn0031378 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011146 - - CG15362 IPR011146:HIT-like domain CG15362 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-25e12.3, Drer\hint3" Scer\HNT1 Cele\hint-3 Xtro\hint3 Mmus\Hint3 Hsap\HINT3 viable FBgn0043358 EP2409 EP2409 http://flybase.org/reports/FBgn0043358 gene - - - EP2409 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "scutellar bristle,ectopic,trichogen cell,tormogen cell" FBgn0033889 CG6701 - http://flybase.org/reports/FBgn0033889 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - "EP(2)2054, EP2054, CG6701" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013087:Zinc finger C2H2-type, IPR026122:Putative helicase MOV-10" CG6701 11-Aug-17 DroID_v2017_08 "Drer\zgc:154086, Drer\mov10b.2, Drer\mov10a, Drer\helz2, Drer\si:dkey-97a13.6, Drer\mov10b.1" "Scer\HCS1, Scer\NAM7" "Cele\C44H9.4, Cele\C05C10.2, Cele\eri-7" "Xtro\mov10l1, Xtro\mov10, Xtro\helz" "Mmus\Helz, Mmus\Mov10, Mmus\Helz2, Mmus\Mov10l1" "Hsap\MOV10, Hsap\HELZ, Hsap\MOV10L1, Hsap\HELZ2" "neuroanatomy defective,visible" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,eye,wing" DRSC07007 IE -1.873015639 -5.027359649 -2.312406222 -4.729090884 0.106441923 0.029536574 FBgn0263346 CG43427 - http://flybase.org/reports/FBgn0263346 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "CG43427, CG31531, CG14653, CG1054, CG31534, CG18253, anon-WO0140519.95, CG1055" "IPR001781:Zinc finger, LIM-type, IPR031865:Domain of unknown function DUF4757" CG43427 11-Aug-17 DroID_v2017_08 "Drer\lmo7a, Drer\lmo7b, Drer\limch1b, Drer\limch1a" - Cele\lim-8 "Xtro\lmo7, Xtro\limch1" "Mmus\Lmo7, Mmus\Limch1, Mmus\Peak1" "Hsap\LIMCH1, Hsap\LMO7" FBgn0019848 anon-XVI anon-XVI http://flybase.org/reports/FBgn0019848 - gene - - - "XV1, anon-XVI" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036352 CG14110 - http://flybase.org/reports/FBgn0036352 protein_coding_gene - - - CG14110 - CG14110 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC10113 K -0.706882289 0.046051323 -0.680232552 0.53803833 5.79262649 0.24583953 FBgn0085695 CG41564 - http://flybase.org/reports/FBgn0085695 protein_coding_gene - - - CG41564 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041715 teu teufel http://flybase.org/reports/FBgn0041715 gene - - - teu - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,melanotic mass phenotype,hyperplasia" "polytene chromosome,melanotic mass,embryonic/larval brain" FBgn0086391 BG02022 - http://flybase.org/reports/FBgn0086391 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - BG02022 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective,behavior defective,recessive" FBgn0084698 Rst(2)Cyr Resistance 2 Cyromazine http://flybase.org/reports/FBgn0084698 gene - - - Rst(2)Cyr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001648 l(1)dn28 lethal (1) discs normal 28 http://flybase.org/reports/FBgn0001648 - gene - - - "l(1)d.norm.-28, l(1)dn28" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038032 CG10096 - http://flybase.org/reports/FBgn0038032 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - "CG32919, anon-WO0140519.58, CG10096" "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG10096 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97m3.1, Drer\far1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR1, Hsap\FAR2" "viable,fertile" FBgn0259986 nab nab http://flybase.org/reports/FBgn0259986 protein_coding_gene transcription cofactor activity ; GO:0003712 | inferred from mutant phenotype inferred from genetic interaction with sqz inferred from genetic interaction with rn inferred from physical interaction with sqz inferred from physical interaction with rn "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from electronic annotation with InterPro:IPR006988, InterPro:IPR006989 neuron development ; GO:0048666 | inferred from mutant phenotype wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006988, InterPro:IPR006989" "nab, CG33545, l(3)SH143, l(2)SH3 143, CG15001, CG15000, dnab, l(3)64Aj, l(3)SH21, dNAB, Nab, NAB" "IPR006988:Nab, N-terminal, IPR006989:NAB co-repressor, domain" CG33545 11-Aug-17 DroID_v2017_08 "Drer\nab1b, Drer\nab1a, Drer\nab2" - Cele\mab-10 "Xtro\nab2, Xtro\nab1" "Mmus\Nab2, Mmus\Nab1" "Hsap\NAB2, Hsap\NAB1" DRSC08456 EK 0.631812525 -0.270517375 1.5351979 0.393439205 -0.763317914 -1.718326725 FBgn0262415 mir-289 mir-289 stem loop http://flybase.org/reports/FBgn0262415 miRNA_gene - - - "mir-289, Dme-miR-289, CR42962, miR-289, CR33605, mir289, dme-miR-289-3p, dme-miR-289-5p" - CR42962 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002446 l(3)S4 lethal (3) S4 http://flybase.org/reports/FBgn0002446 - gene - - - l(3)S4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061147 l(3)S000108b lethal (3) S000108b http://flybase.org/reports/FBgn0061147 gene - - - "0001/08, l(3)S000108b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0039818 CG11318 - http://flybase.org/reports/FBgn0039818 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000832 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000832 cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000832 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "anon-WO0170980.122, anon-WO0170980.121, CG11318, RE14222p" "IPR000203:GPS motif, IPR000832:GPCR, family 2, secretin-like, IPR017981:GPCR, family 2-like" CG11318 11-Aug-17 DroID_v2017_08 "Drer\adgrg3, Drer\adgrl2a, Drer\LOC101884341, Drer\adgre14, Drer\fbn2b, Drer\fbn2a, Drer\adgrb3, Drer\adgrf6, Drer\adgrf3a, Drer\LOC100538279, Drer\adgrl3.1, Drer\LOC101886975, Drer\adgrl1a, Drer\LOC100537181, Drer\adgrf11, Drer\adgrg2a, Drer\adgre10, Drer\adgrd2, Drer\adgrb1a, Drer\adgrg11, Drer\adgrb2, Drer\LOC100536657, Drer\adgrf8, Drer\adgrf3b, Drer\LOC100535070, Drer\adgre5b.3, Drer\adgrg6, Drer\adgrg4a, Drer\adgrg1, Drer\adgrl4" - - "Xtro\adgrd1, Xtro\adgrf3, Xtro\adgrg1, Xtro\adgrf1, Xtro\adgrl1, Xtro\adgre5, Xtro\adgrv1" "Mmus\Adgre4, Mmus\Adgrb2, Mmus\Adgrf1, Mmus\Adgre5, Mmus\Adgrf3, Mmus\Adgrf2, Mmus\Adgrf4, Mmus\Adgrb1, Mmus\Adgrg7, Mmus\Adgrb3, Mmus\Adgrf5, Mmus\Adgrg4, Mmus\Adgrg3, Mmus\Adgrg6, Mmus\Adgrl4, Mmus\Adgrg1, Mmus\Adgrl3, Mmus\Adgrg2, Mmus\Adgrd1, Mmus\Adgre1, Mmus\Adgrg5, Mmus\Adgrl2, Mmus\Adgrl1" "Hsap\ADGRE1, Hsap\ADGRL1, Hsap\CELSR2, Hsap\ADGRL4, Hsap\ADGRL3, Hsap\ADGRL2, Hsap\ADGRB2, Hsap\ADGRB1, Hsap\ADGRG4, Hsap\ADGRG1, Hsap\FBN3, Hsap\ADGRG6, Hsap\ADGRF5, Hsap\ADGRE2, Hsap\ADGRD1, Hsap\ADGRG3, Hsap\ADGRD2, Hsap\ADGRE3, Hsap\ADGRB3, Hsap\ADGRF3, Hsap\ADGRF2, Hsap\ADGRE5, Hsap\ADGRF4, Hsap\ADGRG7, Hsap\ADGRG5, Hsap\ADGRF1, Hsap\ADGRG2" "viable,fertile" FBgn0051121 CG31121 - http://flybase.org/reports/FBgn0051121 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000443108" - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CG18633, CG18655, CG11764, BcDNA:GH19411, CG31121" "IPR003439:ABC transporter-like, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG31121 11-Aug-17 DroID_v2017_08 "Drer\abcg1, Drer\abcg8, Drer\abcg2a, Drer\abcg4a, Drer\abcg4b, Drer\abcg2b, Drer\abcg5" "Scer\ADP1, Scer\PDR10, Scer\YOL075C" Cele\abcx-1 "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg5, Mmus\Abcg3, Mmus\Abcg2, Mmus\Abcg8, Mmus\Abcg4, Mmus\Abcg1" "Hsap\ABCG4, Hsap\ABCG8, Hsap\ABCG1, Hsap\ABCG5" "viable,fertile" DRSC15361 K -0.417248836 -0.133328267 -0.693617711 -0.267799597 1.609321427 0.456881759 FBgn0005058 fs(2)OW104 female sterile (2) OW104 http://flybase.org/reports/FBgn0005058 - gene - - - fs(2)OW104 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260811 EP3-1809 - http://flybase.org/reports/FBgn0260811 gene - - - EP3-1809 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085824 CR41618 - http://flybase.org/reports/FBgn0085824 rRNA_gene - - - CR41618 - CR41618 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024207 ol1 oocyte localisation 1 http://flybase.org/reports/FBgn0024207 - gene - - - ol1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036116 CG7888 - http://flybase.org/reports/FBgn0036116 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 CG7888 "IPR013057:Amino acid transporter, transmembrane domain" CG7888 11-Aug-17 DroID_v2017_08 "Drer\slc36a4, Drer\slc36a1" "Scer\AVT6, Scer\AVT4, Scer\AVT3" "Cele\slc-36.4, Cele\Y43F4B.7, Cele\skat-1, Cele\slc-36.3, Cele\slc-36.2, Cele\slc-36.5" "Xtro\slc36a1, Xtro\slc36a4" "Mmus\Slc36a2, Mmus\Slc38a7, Mmus\Slc36a1, Mmus\Slc36a4, Mmus\Slc36a3" "Hsap\SLC36A1, Hsap\SLC36A2, Hsap\SLC36A4, Hsap\SLC38A7, Hsap\SLC36A3" viable embryonic/larval hemocyte | third instar larval stage FBgn0011581 Ms Myosuppressin http://flybase.org/reports/FBgn0011581 "FBgn0013996, FBgn0039185" protein_coding_gene "neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with MsR1, MsR2 neuropeptide hormone activity ; GO:0005184 | traceable author statement neuropeptide hormone activity ; GO:0005184 | non-traceable author statement" neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern negative regulation of smooth muscle contraction ; GO:0045986 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay negative regulation of heart rate ; GO:0010459 | inferred from direct assay negative regulation of digestive system process ; GO:0060457 | inferred from direct assay adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | traceable author statement negative regulation of heart contraction ; GO:0045822 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "Dms, CG6440, DMS, Drome-MS, Drm-MS, FLRFa, Nems, cg6440, dms, MS, Dm-MS, Ms, MEMS" - CG6440 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable" FBgn0027865 Tsp96F Tetraspanin 96F http://flybase.org/reports/FBgn0027865 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "CG6120, LD19727, Dm.Tsp96F, BcDNA:LD19727, Tsp96F" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG6120 11-Aug-17 DroID_v2017_08 "Drer\tspan35, Drer\tspan37, Drer\upk1a, Drer\tspan11, Drer\tspan4b, Drer\cd9a, Drer\cd151l, Drer\tspan2a, Drer\cd81b, Drer\zgc:171713, Drer\tspan9a, Drer\tspan2b, Drer\cd81a, Drer\tspan18a, Drer\cd9b, Drer\cd151, Drer\tspan18b, Drer\zgc:64051, Drer\tspan4a, Drer\tspan34, Drer\cd82b, Drer\tspan9b, Drer\zgc:65811, Drer\cd82a" - "Cele\tsp-13, Cele\tsp-19, Cele\tsp-5, Cele\tsp-11, Cele\tsp-8, Cele\tsp-10, Cele\tsp-4, Cele\tsp-6" "Xtro\cd53, Xtro\cd37, Xtro\tspan4, Xtro\cd9, Xtro\cd81, Xtro\cd151, Xtro\tspan9, Xtro\cd82, Xtro\tspan2, Xtro\tspan18" "Mmus\Cd81, Mmus\Cd151, Mmus\Tspan2, Mmus\Tspan9, Mmus\Tspan11, Mmus\Tspan4, Mmus\Cd37, Mmus\Cd53, Mmus\Tspan18, Mmus\Upk1a, Mmus\Tspan1, Mmus\Tspan8, Mmus\Upk1b, Mmus\Cd82, Mmus\Cd9" "Hsap\TSPAN11, Hsap\TSPAN16, Hsap\TSPAN18, Hsap\CD53, Hsap\CD82, Hsap\CD151, Hsap\CD9, Hsap\TSPAN9, Hsap\UPK1A, Hsap\UPK1B, Hsap\CD37, Hsap\TSPAN2, Hsap\TSPAN8, Hsap\TSPAN1, Hsap\CD63, Hsap\CD81, Hsap\TSPAN4" "lethal,viable,fertile" FBgn0028220 l(3)S007608 lethal (3) S007608 http://flybase.org/reports/FBgn0028220 gene - - - "0076/08, l(3)S007608" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,recessive" FBgn0020572 anon-62Ea anon-62Ea http://flybase.org/reports/FBgn0020572 - gene - - - anon-62Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000583 eql equatorial-less http://flybase.org/reports/FBgn0000583 - gene - - - eql - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "photoreceptor cell R1,somatic clone,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,ommatidium" FBgn0033968 hui hase und igel http://flybase.org/reports/FBgn0033968 protein_coding_gene molecular_function ; GO:0003674 | no biological data available wing disc development ; GO:0035220 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG10200, hui" - CG10200 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal" "trichogen cell,wing vein L3,wing vein L4,anterior crossvein,wing,posterior,wing margin bristle" FBgn0027572 CG5009 - http://flybase.org/reports/FBgn0027572 - protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012258, InterPro:IPR013786 acyl-CoA oxidase activity ; GO:0003997 | inferred from sequence or structural similarity with UniProtKB:Q15067 acyl-CoA oxidase activity ; GO:0003997 | inferred from sequence or structural similarity with HGNC:119" fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:119 fatty acid oxidation ; GO:0019395 | inferred from sequence or structural similarity with UniProtKB:Q15067 prostaglandin metabolic process ; GO:0006693 | inferred from sequence or structural similarity with UniProtKB:Q15067 lipid metabolic process ; GO:0006629 | inferred from sequence or structural similarity with UniProtKB:Q15067 generation of precursor metabolites and energy ; GO:0006091 | inferred from sequence or structural similarity with UniProtKB:Q15067 "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with UniProtKB:Q15067 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:119,HGNC:120 inferred from sequence model" "BcDNA:GH07485, GH07485, CG5009" "IPR002655:Acyl-CoA oxidase, C-terminal, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR012258:Acyl-CoA oxidase, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR034171:Peroxisomal acyl-coenzyme A oxidase, IPR029320:Acyl-coenzyme A oxidase, N-terminal" CG5009 11-Aug-17 DroID_v2017_08 "Drer\acox1, Drer\acox3" Scer\POX1 "Cele\F59F4.1, Cele\acox-5, Cele\acox-1, Cele\acox-4, Cele\acox-2, Cele\acox-3, Cele\acdh-13" "Xtro\acox1, Xtro\acox2" "Mmus\Acox2, Mmus\Acox3, Mmus\Acox1" "Hsap\ACOX1, Hsap\ACOX3, Hsap\ACOX2" "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0035468 Gr63a Gustatory receptor 63a http://flybase.org/reports/FBgn0035468 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from genetic interaction with Gr21a sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 detection of carbon dioxide ; GO:0003031 | inferred from genetic interaction with Gr21a sensory perception of taste ; GO:0050909 | non-traceable author statement response to carbon dioxide ; GO:0010037 | inferred from mutant phenotype inferred from genetic interaction with Gr21a detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr63F1, CG14979, Gr63a, DmGr63a, GR63a, gr63a" IPR013604:7TM chemoreceptor CG14979 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\sra-8, Cele\lite-1" - - - "neurophysiology defective,recessive,chemosensitive behavior defective,long lived,female limited,oxidative stress response defective,female,smell perception defective" abdominal 1 desC neuron FBgn0060426 l(3)S126615a lethal (3) S126615a http://flybase.org/reports/FBgn0060426 gene - - - "1266/15, l(3)S126615a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029137 Patsas Patsas http://flybase.org/reports/FBgn0029137 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 Golgi apparatus ; GO:0005794 | inferred from direct assay "CG6618, Patsas" "IPR001594:Palmitoyltransferase, DHHC domain, IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG6618 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-223a10.1, Drer\zdhhc17, Drer\zdhhc13" "Scer\PFA4, Scer\ERF2, Scer\SWF1, Scer\AKR1, Scer\AKR2" "Cele\dhhc-13, Cele\dhhc-14" "Xtro\zdhhc13, Xtro\LOC100498452, Xtro\zdhhc17" "Mmus\Ankrd60, Mmus\Zdhhc17, Mmus\Zdhhc12, Mmus\Zdhhc13" "Hsap\ANKRD60, Hsap\ZDHHC13, Hsap\ZDHHC17, Hsap\ZDHHC12" "viable,body color defective" mesothoracic tergum FBgn0015437 l(1)5AEa lethal (1) 5AEa http://flybase.org/reports/FBgn0015437 - gene - - - l(1)5AEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000859 fs(1)M53 female sterile (1) M53 http://flybase.org/reports/FBgn0000859 - gene - - - fs(1)M53 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" FBgn0265494 BG01888 - http://flybase.org/reports/FBgn0265494 gene - - - BG01888 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034223 Tes Testin http://flybase.org/reports/FBgn0034223 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781, InterPro:IPR010442" - cytoplasm ; GO:0005737 | inferred from direct assay actin cytoskeleton ; GO:0015629 | inferred from direct assay "CG6522, Tes, dTES" "IPR001781:Zinc finger, LIM-type, IPR010442:PET domain, IPR033724:PET testin" CG6522 11-Aug-17 DroID_v2017_08 "Drer\tes, Drer\lmcd1" - Cele\tes-1 "Xtro\tes, Xtro\lmcd1" "Mmus\Lmcd1, Mmus\Gm4907, Mmus\Tes" "Hsap\LMCD1, Hsap\TES" viable FBgn0262738 norpA no receptor potential A http://flybase.org/reports/FBgn0262738 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR016280 GTPase activator activity ; GO:0005096 | non-traceable author statement phosphatidylinositol phospholipase C activity ; GO:0004435 | inferred from mutant phenotype phosphatidylinositol phospholipase C activity ; GO:0004435 | traceable author statement phospholipase C activity ; GO:0004629 | traceable author statement "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001192, InterPro:IPR001711 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway ; GO:0051482 | traceable author statement phospholipid metabolic process ; GO:0006644 | traceable author statement detection of chemical stimulus involved in sensory perception of bitter taste ; GO:0001580 | inferred from mutant phenotype rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | inferred from mutant phenotype phospholipid biosynthetic process ; GO:0008654 | traceable author statement calcium-mediated signaling ; GO:0019722 | traceable author statement deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from direct assay phototransduction ; GO:0007602 | inferred from mutant phenotype mucosal immune response ; GO:0002385 | inferred from mutant phenotype thermotaxis ; GO:0043052 | inferred from mutant phenotype entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from genetic interaction with Rh5, Rh6, cry inferred from genetic interaction with Rh5, cry inferred from genetic interaction with Rh6, cry inferred from genetic interaction with cry diacylglycerol biosynthetic process ; GO:0006651 | traceable author statement phototransduction ; GO:0007602 | traceable author statement light-induced release of internally sequestered calcium ion ; GO:0008377 | traceable author statement entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype positive regulation of clathrin-dependent endocytosis ; GO:2000370 | inferred from mutant phenotype phosphatidylinositol metabolic process ; GO:0046488 | inferred from mutant phenotype" rhabdomere ; GO:0016028 | inferred from direct assay inaD signaling complex ; GO:0016027 | inferred from physical interaction with inaD inaD signaling complex ; GO:0016027 | traceable author statement "norpA, PLCbeta, PLC-beta, NorpA, CG3620, PLC, DIP2, CdkA, PI-PLC, nofC, rof, anon-EST:Posey221, x24, x16, x13, x12, NORPA, MRE18" "IPR000008:C2 domain, IPR000909:Phosphatidylinositol-specific phospholipase C, X domain, IPR001192:Phosphoinositide phospholipase C family, IPR001711:Phospholipase C, phosphatidylinositol-specific, Y domain, IPR011992:EF-hand domain pair, IPR015359:Phosphoinositide-specific phospholipase C, EF-hand-like domain, IPR016280:Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR009535:Phospholipase C-beta, conserved site, IPR011993:PH domain-like" CG3620 11-Aug-17 DroID_v2017_08 "Drer\plcb2, Drer\plcb3, Drer\plcb4, Drer\plcb1" Scer\PLC1 "Cele\plc-1, Cele\plc-4, Cele\plc-2, Cele\egl-8" "Xtro\plcb1, Xtro\plcb4, Xtro\plcb3" "Mmus\Plcb4, Mmus\Plcb3, Mmus\Plcb1, Mmus\Plcb2" "Hsap\PLCB3, Hsap\CCDC88B, Hsap\PLCB1, Hsap\PLCB4, Hsap\PLCB2" " adult stage , larval stage , embryonic stage , embryonic stage -- adult stage " " adult thorax

, adult head

, photoreceptor cell

, adult abdomen

, optic lobe

, thoracico-abdominal ganglion

, adult brain

" " adult stage , adult stage | female " " eye

, adult brain

, leg

, thoracico-abdominal ganglion

, retina

, ocellus

, adult head

, adult abdomen

, optic lobe

, adult thorax

" FBgn0265974 ttv tout-velu http://flybase.org/reports/FBgn0265974 protein_coding_gene acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement glucuronosyltransferase activity ; GO:0015020 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y169 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity ; GO:0050509 | inferred from sequence or structural similarity with UniProtKB:O77783 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ; GO:0050508 | inferred from sequence or structural similarity with UniProtKB:O77783 "heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from direct assay heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype decapentaplegic signaling pathway ; GO:0008101 | inferred from mutant phenotype glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | non-traceable author statement synapse organization ; GO:0050808 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from genetic interaction with UniProtKB:Q9Y169 smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with Sdc heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | traceable author statement heparin biosynthetic process ; GO:0030210 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | inferred from mutant phenotype intracellular distribution of mitochondria ; GO:0048312 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | non-traceable author statement N-acetylglucosamine metabolic process ; GO:0006044 | inferred from sequence or structural similarity with UniProtKB:O77783 germ cell migration ; GO:0008354 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR015338 endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement "ttv, CG10117, l(2)SH0631, l(2)SH2 0631, DEXT1, l(2)05282, l(2)00681, P1.15, l(2)k03617, l(2)k00115, Ttv, Ext1, dExt1" "IPR029044:Nucleotide-diphospho-sugar transferases, IPR004263:Exostosin-like, IPR015338:Exostosin , C-terminal" CG10117 11-Aug-17 DroID_v2017_08 "Drer\ext1b, Drer\ext1c, Drer\ext2, Drer\LOC108179064, Drer\LOC101885478, Drer\ext1a" - "Cele\rib-2, Cele\rib-1" "Xtro\ext1, Xtro\ext2" "Mmus\Extl1, Mmus\Ext2, Mmus\Ext1" "Hsap\EXT1, Hsap\EXTL1, Hsap\EXT2" FBgn0031811 CG13982 - http://flybase.org/reports/FBgn0031811 protein_coding_gene - - - CG13982 - CG13982 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050066 CR30066 - http://flybase.org/reports/FBgn0050066 non_protein_coding_gene - - - CR30066 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22956 K 0.268450314 -1.023921737 0.59246633 -0.028937031 -0.900892656 2.660786025 FBgn0031865 Nha1 Na[+]/H[+] hydrogen antiporter 1 http://flybase.org/reports/FBgn0031865 protein_coding_gene "sodium:proton antiporter activity ; GO:0015385 | NOT inferred from direct assay chloride transmembrane transporter activity ; GO:0015108 | inferred from direct assay sodium:proton antiporter activity ; GO:0015385 | inferred from genetic interaction with SGD:S000002864,SGD:S000004128" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR006153 renal sodium ion transport ; GO:0003096 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006153 brush border ; GO:0005903 | inferred from direct assay "DmNHA1, Nha1, CG10806, nha1" IPR006153:Cation/H+ exchanger CG10806 11-Aug-17 DroID_v2017_08 Drer\si:dkey-162b23.4 - "Cele\F41E7.2, Cele\F57G8.5, Cele\F41E7.1" Xtro\slc9b2 "Mmus\Slc9b2, Mmus\Slc9b1" "Hsap\SLC9B2, Hsap\SLC9B1" "viable,fertile" adult Malpighian tubule FBgn0023396 Cbp86A Calmodulin-binding protein 86A http://flybase.org/reports/FBgn0023396 - gene - - - Cbp86A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004475 art aristatarsia http://flybase.org/reports/FBgn0004475 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available art - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" arista FBgn0040351 CG11638 - http://flybase.org/reports/FBgn0040351 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "EG:BACR7A4.12, CG11638, CBP3" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG11638 11-Aug-17 DroID_v2017_08 "Drer\efcab11, Drer\si:ch211-197n1.2, Drer\calm2b, Drer\calb2b, Drer\tnnc1b, Drer\pvalb3, Drer\rhbdl3, Drer\cabp1a, Drer\tnnc2, Drer\cabp2a, Drer\cabp5b, Drer\calm3b, Drer\calm1b, Drer\calm1a, Drer\cabp5a, Drer\pvalb1, Drer\pvalb9, Drer\calm3a, Drer\cabp1b, Drer\efcab2, Drer\calb2a, Drer\scgn, Drer\pvalb6, Drer\pvalb2, Drer\calml4a, Drer\pvalb4, Drer\caln2, Drer\cabp7b, Drer\cabp2b, Drer\caln1, Drer\calm2a, Drer\pvalb8, Drer\calb1, Drer\calml4b, Drer\efcab6, Drer\tnnc1a" "Scer\CMD1, Scer\MLC1, Scer\MLC2" Cele\cal-8 "Xtro\pvalb.1, Xtro\scgn, Xtro\cabp4, Xtro\LOC548651, Xtro\calb1, Xtro\pgm1, Xtro\calm1, Xtro\pvalb, Xtro\calml4, Xtro\tnnc1, Xtro\ocm.2, Xtro\efcab6, Xtro\tnnc2, Xtro\ocm, Xtro\cabp7, Xtro\calm2, Xtro\pvalb.2" "Mmus\Calb1, Mmus\Efcab2, Mmus\Calm4, Mmus\Efcab7, Mmus\Tnnc1, Mmus\Cabp7, Mmus\Cabp4, Mmus\Efcab6, Mmus\Tnnc2, Mmus\Efcab3, Mmus\Caln1, Mmus\Ocm, Mmus\Calml4, Mmus\Rcn3, Mmus\1700023F06Rik, Mmus\Calml3, Mmus\Scgn, Mmus\Efcab11, Mmus\Calm2, Mmus\Rhbdl3, Mmus\Spata21, Mmus\Cabp5, Mmus\Efcab9, Mmus\Cabp2, Mmus\Cabp1, Mmus\Calm3, Mmus\Pvalb, Mmus\Calm1, Mmus\Calb2" "Hsap\CALML5, Hsap\TNNC2, Hsap\PVALB, Hsap\CALM3, Hsap\CABP4, Hsap\RCN3, Hsap\CALML3, Hsap\CALN1, Hsap\EFCAB7, Hsap\EFCAB13, Hsap\EFCAB3, Hsap\EFCAB9, Hsap\CABP1, Hsap\CALB1, Hsap\OCM2, Hsap\EFCAB11, Hsap\CALML6, Hsap\CALM1, Hsap\CABP5, Hsap\CABP7, Hsap\OCM, Hsap\RHBDL3, Hsap\EFCAB6, Hsap\CALM2, Hsap\CABP2, Hsap\CALB2, Hsap\CALML4, Hsap\EFCAB2, Hsap\SPATA21, Hsap\TNNC1, Hsap\SCGN" viable FBgn0000666 fli-385 flightless 385 http://flybase.org/reports/FBgn0000666 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fli-385 - - 11-Aug-17 DroID_v2017_08 - - - - - - flightless FBgn0001904 l(2)22Ae lethal (2) 22Ae http://flybase.org/reports/FBgn0001904 - gene - - - "l(2)neh-18, l(2)neh18, l(2)22Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028584 l(?)rK270 lethal (?) rK270 http://flybase.org/reports/FBgn0028584 gene - - - l(?)rK270 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029055 l(1)G0452 lethal (1) G0452 http://flybase.org/reports/FBgn0029055 gene - - - l(1)G0452 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262187 mir-970 mir-970 stem loop http://flybase.org/reports/FBgn0262187 miRNA_gene - - - "miR-970, mir-970, 970, CR42894, dme-miR-970, dme-miR-970-3p" - CR42894 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable" "wing,wing vein,ectopic" FBgn0003489 sprd spread http://flybase.org/reports/FBgn0003489 "FBgn0011352, FBgn0011501" gene - - - "sd, l(3)rJ407, l(3)j3C3, sprd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die,visible" wing FBgn0005552 l(3)85Fe lethal (3) 85Fe http://flybase.org/reports/FBgn0005552 - gene - - - l(3)85Fe - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039887 CG2053 - http://flybase.org/reports/FBgn0039887 protein_coding_gene - mRNA catabolic process ; GO:0006402 | inferred from electronic annotation with InterPro:IPR007216 negative regulation of translation ; GO:0017148 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 CG2053 "IPR016024:Armadillo-type fold, IPR007216:Rcd1/Caf40, IPR011989:Armadillo-like helical" CG2053 11-Aug-17 DroID_v2017_08 Drer\rqcd1 Scer\CAF40 Cele\ntl-9 Xtro\rqcd1 Mmus\Cnot9 Hsap\CNOT9 viable FBgn0032839 CG10659 - http://flybase.org/reports/FBgn0032839 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 CG10659 "IPR016181:Acyl-CoA N-acyltransferase, IPR000182:GNAT domain" CG10659 11-Aug-17 DroID_v2017_08 - - "Cele\W02D7.5, Cele\M7.12, Cele\M7.8, Cele\W02D7.4, Cele\R05H10.1, Cele\anat-1, Cele\T10B5.4, Cele\R05H10.7" - - - "partially lethal - majority die,some die during pupal stage" FBgn0051472 sgll sugarlethal http://flybase.org/reports/FBgn0051472 protein_coding_gene "FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR011576, InterPro:IPR012349 pyridoxamine-phosphate oxidase activity ; GO:0004733 | inferred from mutant phenotype" "pyridoxine biosynthetic process ; GO:0008615 | inferred from electronic annotation with InterPro:IPR000659 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000659, InterPro:IPR011576, InterPro:IPR012349, InterPro:IPR019576, InterPro:IPR019740 pyridoxal phosphate biosynthetic process ; GO:0042823 | inferred from mutant phenotype vitamin B6 metabolic process ; GO:0042816 | inferred from mutant phenotype response to sucrose ; GO:0009744 | inferred from mutant phenotype" - "CG2649, CG31472, sgll, dPNPO" "IPR000659:Pyridoxamine 5'-phosphate oxidase, IPR011576:Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain, IPR012349:FMN-binding split barrel, IPR019576:Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal, IPR019740:Pyridoxamine 5'-phosphate oxidase, conserved site" CG31472 11-Aug-17 DroID_v2017_08 Drer\pnpo Scer\PDX3 Cele\F57B9.1 Xtro\pnpo Mmus\Pnpo Hsap\PNPO "short lived,nutrition conditional,chemical sensitive,partially lethal - majority die" FBgn0016682 Mrp53 Mrp53 http://flybase.org/reports/FBgn0016682 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from direct assay "mrp53, Mrp53" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020845 l(2)122 lethal (2) 122 http://flybase.org/reports/FBgn0020845 - gene - - - "T(2;3)Hin122, l(2)122" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004613 Walker Walker http://flybase.org/reports/FBgn0004613 - gene - - - "Wk, Walker" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,conditional,lethal,recessive,dominant" "wing,conditional,wing disc" FBgn0086224 Cdl-1 CID delocalization-1 http://flybase.org/reports/FBgn0086224 gene - - - "Cdl-1, CDL-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005033 E(Pc)a Enhancer of Polycomb a http://flybase.org/reports/FBgn0005033 - gene - - - E(Pc)a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant,homeotic" "mesothoracic leg,metathoracic leg,embryonic abdominal segment 1,embryonic abdominal segment 4" FBgn0005029 dta delta wing http://flybase.org/reports/FBgn0005029 - gene - - - dta - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,female sterile,recessive" wing FBgn0264666 tiny-tubes tiny tubes http://flybase.org/reports/FBgn0264666 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - tiny-tubes - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0001123 Galphas G protein alpha s subunit http://flybase.org/reports/FBgn0001123 - protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000367 G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 adenylate cyclase-activating dopamine receptor signaling pathway ; GO:0007191 | inferred from biological aspect of ancestor with PANTHER:PTN000026754 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from genetic interaction with fz chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype instar larval or pupal development ; GO:0002165 | non-traceable author statement response to trehalose ; GO:0010353 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype inferred from genetic interaction with Bx imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of feeding behavior ; GO:2000253 | inferred from genetic interaction with sNPF-R behavioral response to cocaine ; GO:0048148 | non-traceable author statement learning or memory ; GO:0007611 | non-traceable author statement visual behavior ; GO:0007632 | non-traceable author statement chaeta development ; GO:0022416 | inferred from mutant phenotype inferred from genetic interaction with Chi neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype basement membrane ; GO:0005604 | inferred from direct assay heterotrimeric G-protein complex ; GO:0005834 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "Galpha[[s]], Galpha60A, dgs, Gs-alpha60A, GSalpha, G[[s]]alpha, Gs, GalphaS, Galphas, G[[S]]alpha, Gsalpha, dgsalpha, G-salpha60A, dG[[alphas]], G-alpha-60A, CG2835, DGs, DGsalpha, Gsalpha60A, G[[s]], G[[alphas]], GNAS/L, G[[s]]-alpha-60A, G-5alpha, Gs-alpha, G-salpha 60A, Gaalpha, Galpha[[s]]60A, Galphas60A, galphas" "IPR000367:G-protein alpha subunit, group S, IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2835 11-Aug-17 DroID_v2017_08 "Drer\gnal, Drer\gnal2, Drer\gnas" "Scer\GPA2, Scer\GPA1" "Cele\gpa-18, Cele\gsa-1, Cele\gpa-10, Cele\gpa-5" "Xtro\gnas, Xtro\gnal" "Mmus\Gnal, Mmus\Gnas" "Hsap\GNAL, Hsap\GNAS" " embryonic stage--pupal stage , adult stage " " adult brain cortex

, adult head

, eye

" " adult stage && oogenesis stage , adult stage , embryonic stage | stage >8 " " follicle cell

, neuropil adult brain

, adult antennal nerve | restricted

, neuropil thoracic ganglion

, adult brain cortex

, organism

" "lethal,recessive,taste perception defective,circadian rhythm defective,wild-type,viable,hypoactive,developmental rate defective,locomotor behavior defective,neurophysiology defective,behavior defective,immune response defective,decreased cell death,somatic clone,smell perception defective,visible,memory defective,increased cell death,learning defective,locomotor rhythm defective,visual behavior defective" "sensory neuron & labellar taste bristle,gustatory receptor neuron,large labellar taste bristle,wing,posterior scutellar bristle,pupa,bouton,synapse,embryonic/larval fat body,labellar taste bristle,somatic clone,adult olfactory receptor neuron Or22,scutellum,wing | pharate adult stage,photoreceptor cell" FBgn0266841 CR45303 - http://flybase.org/reports/FBgn0266841 non_protein_coding_gene - - - CR45303 - CR45303 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031627 CG15630 - http://flybase.org/reports/FBgn0031627 protein_coding_gene - - - "CT35785, CG31970, CG15630, 15630" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG15630 11-Aug-17 DroID_v2017_08 "Drer\ncam1a, Drer\ncam1b" - "Cele\zig-1, Cele\zig-6" Xtro\ncam2 "Mmus\Ncam2, Mmus\Ncam1" "Hsap\NCAM1, Hsap\NCAM2" "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0000858 fs(1)M52 female sterile (1) M52 http://flybase.org/reports/FBgn0000858 - gene - - - fs(1)M52 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0266592 CR45117 - http://flybase.org/reports/FBgn0266592 non_protein_coding_gene - - - CR45117 - CR45117 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065104 snmRNA:158 small non-messenger RNA 158 http://flybase.org/reports/FBgn0065104 non_protein_coding_gene - - - "Dm-158, CR33749, snmRNA:158" - CR33749 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065158 l(3)SH047 lethal (3) SH047 http://flybase.org/reports/FBgn0065158 gene - - - "l(3)SH047, l(2)SH3 047" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002612 M(3)63B Minute (3) 63B http://flybase.org/reports/FBgn0002612 - gene - - - "l(3)63bf, l(3)63Bf, M(3)LS3, M(3)63Bf, M(3)63B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024603 olfS51 olfactory S51 http://flybase.org/reports/FBgn0024603 - gene - - - olfS51 - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0035994 CG14179 - http://flybase.org/reports/FBgn0035994 protein_coding_gene - - - CG14179 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019779 l(1)30 lethal (1) 30 http://flybase.org/reports/FBgn0019779 - gene - - - l(1)30 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050026 CG30026 - http://flybase.org/reports/FBgn0050026 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30026 - CG30026 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052675 Tango5 Transport and Golgi organization 5 http://flybase.org/reports/FBgn0052675 protein_coding_gene molecular_function ; GO:0003674 | no biological data available exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 Golgi organization ; GO:0007030 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 protein secretion ; GO:0009306 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 endoplasmic reticulum ; GO:0005783 | inferred from direct assay pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 "CG32675, TANGO5, CG1534, Tango5" - CG32675 11-Aug-17 DroID_v2017_08 Drer\vmp1 - Cele\epg-3 Xtro\vmp1 Mmus\Vmp1 Hsap\VMP1 viable FBgn0035588 CG10672 - http://flybase.org/reports/FBgn0035588 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:16985 inferred from sequence model "CG10672, DHRS4" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR029511:Dehydrogenase/reductase SDR member 4-like, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG10672 11-Aug-17 DroID_v2017_08 "Drer\spra, Drer\pecr, Drer\decr2, Drer\dhrs4, Drer\hsdl2, Drer\dhrs1, Drer\zgc:113054, Drer\decr1, Drer\hsd17b14, Drer\bdh2" "Scer\OAR1, Scer\IRC24, Scer\YMR226C, Scer\SPS19" "Cele\R05D8.7, Cele\R119.3, Cele\dhs-13, Cele\dhrs-4" "Xtro\hsd17b14, Xtro\pecr, Xtro\MGC147226, Xtro\hsdl2, Xtro\dhrs4, Xtro\decr1, Xtro\decr2, Xtro\spr" "Mmus\Hsdl2, Mmus\Decr1, Mmus\Dhrs1, Mmus\Pecr, Mmus\Spr, Mmus\Dhrs4, Mmus\Hsd17b14, Mmus\Bdh2, Mmus\Dhrs2, Mmus\Decr2" "Hsap\HSD17B14, Hsap\DHRS4L1, Hsap\HSDL2, Hsap\PECR, Hsap\BDH2, Hsap\DHRS4L2, Hsap\DECR2, Hsap\SPR, Hsap\DHRS1, Hsap\DHRS4, Hsap\DECR1, Hsap\DHRS2" viable FBgn0002804 ms(1)19Fc male sterile (1) 19Fc http://flybase.org/reports/FBgn0002804 - gene - - - ms(1)19Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0069230 gl(2L)266-11 gl(2L)266-11 http://flybase.org/reports/FBgn0069230 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)266-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment,filzkorper" FBgn0063379 snoRNA:U31:54Ec snoRNA:U31:54Ec http://flybase.org/reports/FBgn0063379 snoRNA_gene - - - "U31snoRNA, CR32898, snoRNA:U31:54Ec" - CR32898 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011844 tRNA:Asp-GTC-1-10 transfer RNA:Aspartic acid-GTC 1-10 http://flybase.org/reports/FBgn0011844 "FBgn0052125, FBgn0060265" tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "AE002602.trna20-AspGTC, tRNA:D:GTC:AE002602, CR32125, tRNA:asp2:69F, tRNA[[Asp]], tRNA[Asp-GTC], chr3L.trna26-AspGTC, tRNA:Asp-GTC-1-10, tRNA:D2:69F, tRNA-Asp-GTC-1-10, GAC" - CR32125 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040766 CG13235 - http://flybase.org/reports/FBgn0040766 protein_coding_gene - - - CG13235 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036900 CG8765 - http://flybase.org/reports/FBgn0036900 protein_coding_gene molecular_function ; GO:0003674 | no biological data available lateral inhibition ; GO:0046331 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG8765 IPR006578:MADF domain CG8765 11-Aug-17 DroID_v2017_08 "Drer\zgc:152938, Drer\si:ch211-207i20.3, Drer\LOC100330838" - "Cele\madf-3, Cele\madf-5, Cele\madf-9, Cele\madf-10, Cele\madf-2, Cele\madf-4, Cele\madf-8" - - - "neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "dorsal multidendritic neuron ddaD,ventral multidendritic neuron vdaB,chaeta,trichogen cell,supernumerary,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa" FBgn0262460 mir-2a-2 mir-2a-2 stem loop http://flybase.org/reports/FBgn0262460 miRNA_gene - negative regulation of translational initiation ; GO:0045947 | inferred from direct assay negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "mir-2a-2, mir-2a, miR-2, dme-mir-2a-2, miR-2a, 2a-2, MIR-2, CR43035, miR2a, miR2-a, miR-2a-2, mir-2, CR32966, miR2, dme-miR-2a" - CR43035 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage viable FBgn0267724 CR46057 - http://flybase.org/reports/FBgn0267724 non_protein_coding_gene - - - CR46057 - CR46057 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005584 MabF7D6 MabF7D6 http://flybase.org/reports/FBgn0005584 "FBgn0004489, FBgn0004909" gene protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from direct assay extrinsic component of plasma membrane ; GO:0019897 | traceable author statement "F7D6, MabF7D6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259824 Hip14 Huntingtin-interacting protein 14 http://flybase.org/reports/FBgn0259824 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype positive regulation of protein secretion ; GO:0050714 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 Golgi apparatus ; GO:0005794 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay "hip14, CG6017, 3L1, Hip14, dHIP14, l(3)72Ad, CG 6017" "IPR001594:Palmitoyltransferase, DHHC domain, IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG6017 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-223a10.1, Drer\zdhhc13, Drer\zdhhc17" "Scer\AKR2, Scer\AKR1" "Cele\dhhc-13, Cele\dhhc-14" "Xtro\zdhhc17, Xtro\zdhhc13" "Mmus\Zdhhc13, Mmus\Zdhhc17, Mmus\Ankrd35" "Hsap\ZDHHC17, Hsap\ZDHHC13, Hsap\ANKRD35" FBgn0265218 fs(2)Z2-931 - http://flybase.org/reports/FBgn0265218 gene - - - fs(2)Z2-931 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0000977 fs(2)HO144 female sterile (2) HO144 http://flybase.org/reports/FBgn0000977 - gene - - - "fs(2)144A, fs(2)HO144" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011670 Mst57Dc Male-specific transcript 57Dc http://flybase.org/reports/FBgn0011670 FBgn0002859 protein_coding_gene molecular_function ; GO:0003674 | no biological data available oviposition ; GO:0018991 | non-traceable author statement post-mating behavior ; GO:0045297 | non-traceable author statement multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | non-traceable author statement "CG4986, Acp57Dc, mst-1, mst(2)ag-1, Mst57Dc, Mst75Dc" - CG4986 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016661 H2 haemolymph protein 2 http://flybase.org/reports/FBgn0016661 - gene - - - H2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019828 dj don juan http://flybase.org/reports/FBgn0019828 - protein_coding_gene - sperm individualization ; GO:0007291 | inferred from expression pattern spermatogenesis ; GO:0007283 | traceable author statement motile cilium ; GO:0031514 | inferred from direct assay axoneme ; GO:0005930 | inferred from direct assay mitochondrial derivative ; GO:0016007 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DJ, bs02h03.y1, CG1980, dj, Dj" - CG1980 11-Aug-17 DroID_v2017_08 - - - - - - " spermatogenesis && adult stage | male , spermatogenesis && adult stage " " spermatid

, testis

, spermatid axoneme

" spermatogenesis && adult stage testis

"male sterile,fertile,male,viable" "investment cone,individualization stage spermatid,spermatid,Nebenkern" FBgn0001170 H2.0 Homeodomain protein 2.0 http://flybase.org/reports/FBgn0001170 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG11607, H2.0" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG11607 11-Aug-17 DroID_v2017_08 "Drer\lbx1b, Drer\pnx, Drer\tlx2, Drer\tlx3b, Drer\barhl1b, Drer\ved, Drer\hlx1, Drer\vox, Drer\barx2, Drer\lbx1a, Drer\tlx1, Drer\nkx1.2lb, Drer\barx1, Drer\lbx2, Drer\LOC100008066, Drer\dbx1b, Drer\barhl2" Scer\YOX1 - "Xtro\hlx, Xtro\nkx1-2, Xtro\dbx1, Xtro\tlx2, Xtro\ventx1.2, Xtro\barx1, Xtro\tlx3, Xtro\nkx1-1, Xtro\barhl1, Xtro\tlx1, Xtro\barhl2" "Mmus\Barhl1, Mmus\Tlx2, Mmus\Barhl2, Mmus\Lbx1, Mmus\Lbx2, Mmus\Nkx1-2, Mmus\Tlx3, Mmus\Barx2, Mmus\Barx1, Mmus\Tlx1, Mmus\Dbx2, Mmus\Dbx1, Mmus\Hlx, Mmus\Nkx1-1" "Hsap\BARHL1, Hsap\TLX1, Hsap\DBX1, Hsap\TLX2, Hsap\BARX2, Hsap\HLX, Hsap\BARX1, Hsap\DBX2, Hsap\BARHL2, Hsap\NKX1-1, Hsap\LBX1, Hsap\TLX3, Hsap\LBX2" " embryonic stage -- adult stage , embryonic stage | stage >=11 , embryonic stage | stage >11 " " visceral mesoderm &&of embryonic/larval midgut

, visceral mesoderm

, ectoderm

" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC03340 I -1.03811596 -3.330961788 -0.917033195 -1.251390723 1.374880874 0.496682223 FBgn0027793 CG14787 - http://flybase.org/reports/FBgn0027793 - protein_coding_gene - - - "EG:BACN32G11.4, CG14787" IPR029045:ClpP/crotonase-like domain CG14787 11-Aug-17 DroID_v2017_08 "Drer\zgc:92030, Drer\cdyl" "Scer\DCI1, Scer\ECI1" Cele\ech-4 Xtro\eci2 "Mmus\Cdyl, Mmus\Eci2, Mmus\Cdyl2, Mmus\Eci3" "Hsap\CDY1, Hsap\CDY2B, Hsap\CDY1B, Hsap\ECI2, Hsap\CDYL2, Hsap\CDY2A, Hsap\CDYL" "viable,visible" mesothoracic tergum FBgn0037543 CG10903 - http://flybase.org/reports/FBgn0037543 protein_coding_gene rRNA (guanine) methyltransferase activity ; GO:0016435 | inferred from biological aspect of ancestor with PANTHER:PTN000296553 neurogenesis ; GO:0022008 | inferred from mutant phenotype rRNA (guanine-N7)-methylation ; GO:0070476 | inferred from biological aspect of ancestor with PANTHER:PTN000296553 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000296553 CG10903 "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR022238:Uncharacterised protein family, methyltransferase, Williams-Beuren syndrome" CG10903 11-Aug-17 DroID_v2017_08 "Drer\wbscr22, Drer\wbscr27" Scer\BUD23 Cele\C27F2.4 "Xtro\wbscr27, Xtro\wbscr22" "Mmus\Wbscr27, Mmus\Wbscr22" "Hsap\WBSCR22, Hsap\WBSCR27" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0036822 NijB Ninjurin B http://flybase.org/reports/FBgn0036822 protein_coding_gene - tissue regeneration ; GO:0042246 | inferred from electronic annotation with InterPro:IPR007007 cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR007007 lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007007 "NijB, CG11637" IPR007007:Ninjurin CG11637 11-Aug-17 DroID_v2017_08 "Drer\ninj2, Drer\si:ch1073-278o19.1" - - Xtro\ninj1 "Mmus\Ninj1, Mmus\Ninj2" "Hsap\NINJ1, Hsap\NINJ2" "viable,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell" FBgn0038311 CG14864 - http://flybase.org/reports/FBgn0038311 protein_coding_gene - - - "BcDNA:AT13896, CG14864" - CG14864 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015893 anon-84Fb T3 transcript http://flybase.org/reports/FBgn0015893 - gene - - - "T3, anon-84Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050400 CG30400 - http://flybase.org/reports/FBgn0050400 protein_coding_gene - - - CG30400 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031357 mRpL48 mitochondrial ribosomal protein L48 http://flybase.org/reports/FBgn0031357 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial ribosome ; GO:0005761 | inferred from electronic annotation with InterPro:IPR027487 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CG17642, MRP-L48, mRpL48" "IPR027486:Ribosomal protein S10 domain, IPR027487:Mitochondrial ribosomal protein L48" CG17642 11-Aug-17 DroID_v2017_08 Drer\mrpl48 Scer\RSM10 Cele\CD4.3 Xtro\mrpl48 Mmus\Mrpl48 Hsap\MRPL48 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC00506 K 0.217576332 -1.126800122 -0.352704555 0.015061553 1.631085042 0.50270573 FBgn0029719 CG15473 - http://flybase.org/reports/FBgn0029719 protein_coding_gene - - - CG15473 - CG15473 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC18056 K 0.526024992 0.755893012 0.235942662 0.040160142 0.259373796 1.648847487 FBgn0035209 msd1 mitotic spindle density 1 http://flybase.org/reports/FBgn0035209 protein_coding_gene - microtubule nucleation ; GO:0007020 | inferred from direct assay mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay HAUS complex ; GO:0070652 | colocalizes_with inferred from direct assay "msd1, CG13914, Dgt9" - CG13914 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile,meiotic cell cycle defective,mitotic cell cycle defective,fertile" spindle FBgn0259738 CG42392 - http://flybase.org/reports/FBgn0259738 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42392 - CG42392 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042184 CG18189 - http://flybase.org/reports/FBgn0042184 protein_coding_gene - - - CG18189 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020508 Ag5r2 Antigen 5-related 2 http://flybase.org/reports/FBgn0020508 FBgn0030579 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "Agr2, CG9540, Ag5r2" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR002413:Ves allergen, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG9540 11-Aug-17 DroID_v2017_08 "Drer\glipr2, Drer\LOC100536500, Drer\glipr1b, Drer\crispld2, Drer\pi15a, Drer\glipr2l, Drer\crispld1a, Drer\r3hdml, Drer\crispld1b, Drer\pi15b, Drer\LOC101883528" "Scer\PRY1, Scer\PRY3, Scer\PRY2" "Cele\scl-13, Cele\scl-10, Cele\scl-8, Cele\scl-12, Cele\scl-23, Cele\scl-18, Cele\scl-17, Cele\scl-21, Cele\scl-27, Cele\scl-11, Cele\scl-19, Cele\scl-7, Cele\scl-6, Cele\scl-14, Cele\scl-1, Cele\scl-15, Cele\scl-2, Cele\scl-5, Cele\scl-3, Cele\scl-20, Cele\scl-9" "Xtro\glipr2, Xtro\pi15, Xtro\crisp2, Xtro\MGC108118, Xtro\crisp3, Xtro\crisp1, Xtro\r3hdml, Xtro\crispld2" "Mmus\Crisp2, Mmus\Crisp4, Mmus\R3hdml, Mmus\Crispld1, Mmus\Glipr1l1, Mmus\Glipr1l2, Mmus\Crisp1, Mmus\Clec18a, Mmus\Glipr2, Mmus\Glipr1, Mmus\Pi15, Mmus\Crisp3, Mmus\Crispld2, Mmus\Pi16" "Hsap\CRISP2, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\PI15, Hsap\GLIPR1, Hsap\R3HDML, Hsap\CRISPLD2, Hsap\CLEC18A, Hsap\CRISPLD1, Hsap\CLEC18B, Hsap\GLIPR2, Hsap\CLEC18C, Hsap\CRISP1, Hsap\PI16" " larval stage , embryonic stage | stage 15 , embryonic stage | stage >=15 " " midgut constriction 3 | posterior to

, posterior embryonic/larval midgut | restricted

" viable FBgn0031999 CG8419 - http://flybase.org/reports/FBgn0031999 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:2685973 zinc ion binding ; GO:0008270 | inferred from sequence model" protein autoubiquitination ; GO:0051865 | inferred from sequence or structural similarity with MGI:MGI:2685973 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR000315 cellular_component ; GO:0005575 | no biological data available CG8419 "IPR000315:B-box-type zinc finger, IPR001298:Filamin/ABP280 repeat, IPR001841:Zinc finger, RING-type, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR017868:Filamin/ABP280 repeat-like, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027370:RING-type zinc-finger, LisH dimerisation motif" CG8419 11-Aug-17 DroID_v2017_08 "Drer\trim35-13, Drer\trim59, Drer\si:ch211-193i15.2, Drer\btr05, Drer\si:ch73-166o21.1, Drer\btr07, Drer\btr04, Drer\btr32, Drer\trim35-25, Drer\trim35-3, Drer\trim35-23, Drer\btr33, Drer\trim35-10, Drer\trim35-20, Drer\btr29, Drer\si:ch73-106l15.2, Drer\ftr72, Drer\ftr14l, Drer\ftr88, Drer\ftr83, Drer\ftr87, Drer\trim13, Drer\trim35-39, Drer\ftr84, Drer\trim35-31, Drer\trim35-24, Drer\trim35-19, Drer\trim35-34, Drer\ftr91, Drer\si:ch211-247l8.10, Drer\si:ch73-364h19.2, Drer\trim35-30, Drer\ftr76, Drer\trim62, Drer\trim35-40, Drer\si:ch211-12p12.2, Drer\zgc:173581, Drer\trim35-29, Drer\ftr73, Drer\si:ch211-276c2.4, Drer\trim35-35, Drer\zmp:0000001316, Drer\btr24, Drer\si:ch211-120g10.1, Drer\trim35-22, Drer\btr16, Drer\trim35-7, Drer\btr22, Drer\trim35-33, Drer\zgc:194990, Drer\ftr86, Drer\btr26, Drer\trim35-14, Drer\btr18, Drer\btr01, Drer\ftr82, Drer\btr02, Drer\btr21, Drer\btr09, Drer\si:dkey-37m8.11, Drer\si:dkey-46i9.6, Drer\btr06, Drer\trim45, Drer\btr20, Drer\trim35-27, Drer\btr12, Drer\trim35-12, Drer\si:ch1073-324l1.1, Drer\si:ch211-247l8.8, Drer\trim105, Drer\si:dkey-219e21.2, Drer\si:ch211-175l6.2, Drer\trim35-21, Drer\trim35-36" - "Cele\nhl-2, Cele\madd-2" Xtro\trim45 "Mmus\Trim35, Mmus\Trim14, Mmus\Trim62, Mmus\Trim29, Mmus\Trim65, Mmus\Trim44, Mmus\Trim41, Mmus\Trim13, Mmus\Trim45" "Hsap\TRIM62, Hsap\TRIM29, Hsap\TRIM35, Hsap\TRIM13, Hsap\TRIM45, Hsap\TRIM14, Hsap\TRIM41, Hsap\TRIM65, Hsap\TRIM44" viable FBgn0011179 l(1)291-82 lethal (1) 291-82 http://flybase.org/reports/FBgn0011179 FBgn0010199 gene - - - "291-82, l(1)291-82" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022343 CG3760 - http://flybase.org/reports/FBgn0022343 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon2C9, anon-fe2C9, anon-EST:fe2C9, CG3760" IPR026806:Protein CDV3 CG3760 11-Aug-17 DroID_v2017_08 Drer\cdv3 - - Xtro\cdv3 Mmus\Cdv3 Hsap\CDV3 "viable,fertile" FBgn0267465 CR45815 - http://flybase.org/reports/FBgn0267465 non_protein_coding_gene - - - CR45815 - CR45815 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050316 tRNA:Arg-ACG-1-4 transfer RNA:Arginine-ACG 1-4 http://flybase.org/reports/FBgn0050316 tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "AE002769.trna17-ArgACG, tRNA:R:ACG:AE002769-e, CR30316, chr2R.trna9-ArgACG, tRNA-Arg-ACG-1-4, tRNA:Arg-ACG-1-4, tRNA:CR30316, CGU" - CR30316 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043897 gsb::prd gsb::prd http://flybase.org/reports/FBgn0043897 engineered_fusion_gene - - - gsb::prd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052557 CG32557 - http://flybase.org/reports/FBgn0052557 protein_coding_gene "copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR002355, InterPro:IPR011706, InterPro:IPR011707 iron ion transmembrane transporter activity ; GO:0005381 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001709969 ferroxidase activity ; GO:0004322 | inferred from biological aspect of ancestor with PANTHER:PTN001709969" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001117, InterPro:IPR011706 iron assimilation by reduction and transport ; GO:0033215 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 iron ion transport ; GO:0006826 | inferred from biological aspect of ancestor with PANTHER:PTN001709969" high-affinity iron permease complex ; GO:0033573 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 "CG7871, CG32557, MCO4" "IPR001117:Multicopper oxidase, type 1, IPR002355:Multicopper oxidase, copper-binding site, IPR008972:Cupredoxin, IPR011706:Multicopper oxidase, type 2, IPR011707:Multicopper oxidase, type 3" CG32557 11-Aug-17 DroID_v2017_08 "Drer\hephl1b, Drer\cp" "Scer\FET3, Scer\GMC1, Scer\FET5" Cele\F21D5.3 Xtro\hephl1 "Mmus\Hephl1, Mmus\Cp, Mmus\Heph" "Hsap\HEPH, Hsap\HEPHL1, Hsap\CP" viable FBgn0011103 l(1)Q64 lethal (1) Q64 http://flybase.org/reports/FBgn0011103 FBgn0010210 gene - - - l(1)Q64 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031831 COX5BL Cytochrome c oxidase subunit 5B-like http://flybase.org/reports/FBgn0031831 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P10606 cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000012880 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000012880 mitochondrial ATP synthesis coupled proton transport ; GO:0042776 | inferred from biological aspect of ancestor with PANTHER:PTN000012880 mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProtKB:P10606" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P10606 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000012880 "Vb, CG11043, COXB, COX5BL" "IPR002124:Cytochrome c oxidase, subunit Vb" CG11043 11-Aug-17 DroID_v2017_08 "Drer\zgc:86599, Drer\cox5b2, Drer\cox5b1" Scer\COX4 Cele\cco-1 "Xtro\cox5b.1, Xtro\cox5b.2" Mmus\Cox5b Hsap\COX5B "viable,visible" trichogen cell FBgn0005701 l(1)TK104 lethal (1) TK104 http://flybase.org/reports/FBgn0005701 - gene - - - "l104, l(1)TK104" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" eye FBgn0011723 byn brachyenteron http://flybase.org/reports/FBgn0011723 FBgn0014890 protein_coding_gene "protein homodimerization activity ; GO:0042803 | inferred from physical interaction with byn DNA binding ; GO:0003677 | inferred from sequence or structural similarity with MGI:MGI:98472 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay" hindgut morphogenesis ; GO:0007442 | inferred from expression pattern inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | traceable author statement midgut development ; GO:0007494 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | traceable author statement pole cell migration ; GO:0007280 | traceable author statement cell fate determination ; GO:0001709 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "Dm-BYN, byn/apro, Byn, Trg, trg, dm-Trg, DTrg, D-TRA, apro, Tra, D-Trg, CG7260, byn, Bra" "IPR001699:Transcription factor, T-box, IPR002070:Transcription factor, Brachyury, IPR008967:p53-like transcription factor, DNA-binding, IPR018186:Transcription factor, T-box, conserved site" CG7260 11-Aug-17 DroID_v2017_08 "Drer\eomesa, Drer\tbr1b, Drer\tb, Drer\tbx5a, Drer\mgaa, Drer\tbr1a, Drer\tbx3a, Drer\tbx2a, Drer\tbx21, Drer\tbx16, Drer\tbx3b, Drer\tbx5b, Drer\ta, Drer\tbx2b, Drer\tbx19, Drer\tbx6, Drer\eomesb, Drer\tbx4, Drer\tbx6l" - "Cele\tbx-8, Cele\tbx-42, Cele\tbx-38, Cele\tbx-33, Cele\tbx-43, Cele\tbx-36, Cele\tbx-40, Cele\tbx-37, Cele\tbx-11, Cele\tbx-39, Cele\tbx-35, Cele\tbx-9, Cele\sea-1" "Xtro\tbx2, Xtro\vegt, Xtro\tbx4, Xtro\tbx3, Xtro\t, Xtro\t2, Xtro\tbr1, Xtro\tbx5, Xtro\eomes, Xtro\mga" "Mmus\Tbx4, Mmus\Tbx6, Mmus\Mga, Mmus\T, Mmus\Tbx21, Mmus\Tbx3, Mmus\Tbx2, Mmus\Tbx5, Mmus\Eomes, Mmus\Tbx19, Mmus\Tbr1" "Hsap\TBX2, Hsap\TBX3, Hsap\EOMES, Hsap\MGA, Hsap\TBX21, Hsap\T, Hsap\TBX6, Hsap\TBX5, Hsap\TBX19, Hsap\TBR1, Hsap\TBX4" " embryonic stage | stage 5-10 , embryonic stage | stage 5 , embryonic stage , embryonic stage | cycle 14 " " proctodeum

,

0-10% egg length , embryonic/larval hindgut

,

posterior ,

0-20% egg length , anal pad

" " embryonic stage , embryonic stage | stage 5-10 " " embryonic/larval hindgut

, proctodeum

, anal pad

" "lethal,recessive,short lived,partially,female sterile,viable,body color defective" "proctodeum,hindgut proper primordium,embryonic anal pad,egg chamber,adult Malpighian tubule Type II cell,longitudinal visceral muscle primordium,germline cell,longitudinal visceral muscle fiber,circular visceral muscle fiber,midgut constriction 1,midgut constriction 2,midgut constriction 3,embryonic/larval hindgut,embryonic/larval dorsal vessel,pericardial cell,A1-7 dorsal acute muscle 1,Malpighian tubule,midgut constriction,head mesoderm,ectopic,mesoderm,mesothoracic tergum" FBgn0266982 CR45433 - http://flybase.org/reports/FBgn0266982 non_protein_coding_gene - - - CR45433 - CR45433 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031622 CG3251 - http://flybase.org/reports/FBgn0031622 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:24949 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | NOT inferred from direct assay protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:24949 protein deubiquitination ; GO:0016579 | NOT inferred from direct assay cellular_component ; GO:0005575 | no biological data available CG3251 IPR003323:OTU domain CG3251 11-Aug-17 DroID_v2017_08 "Drer\zgc:92907, Drer\alg13" Scer\ALG13 "Cele\otub-4, Cele\algn-13" "Xtro\otud4, Xtro\alg13" "Mmus\Otud4, Mmus\Alg13, Mmus\Glt28d2, Mmus\Otud1, Mmus\Otud5" "Hsap\ALG13, Hsap\OTUD4, Hsap\OTUD5, Hsap\OTUD1" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum,scutellar bristle" FBgn0082166 ph-PRE ph-PRE http://flybase.org/reports/FBgn0082166 regulatory_region - - - "ph-PRE, Ph" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060293 smet smetana http://flybase.org/reports/FBgn0060293 gene molecular_function ; GO:0003674 | no biological data available temperature compensation of the circadian clock ; GO:0010378 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available smet - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,locomotor behavior defective,locomotor rhythm defective" FBgn0030377 CG1924 - http://flybase.org/reports/FBgn0030377 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001580, InterPro:IPR009033, InterPro:IPR018124 unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001580" protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001580 endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR001580 CG1924 "IPR001580:Calreticulin/calnexin, IPR009033:Calreticulin/calnexin, P domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR018124:Calreticulin/calnexin, conserved site" CG1924 11-Aug-17 DroID_v2017_08 "Drer\canx, Drer\clgn, Drer\si:ch211-274f20.2" Scer\CNE1 "Cele\crt-1, Cele\cnx-1" Xtro\canx "Mmus\Canx, Mmus\Calr, Mmus\Clgn" "Hsap\CLGN, Hsap\CANX, Hsap\CALR" FBgn0050404 Tango11 Transport and Golgi organization 11 http://flybase.org/reports/FBgn0050404 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein secretion ; GO:0009306 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay "CG30404, TANGO11, BEST:LD33633, anon-EST:fe1F11, BcDNA:LD22567, Tango11, tango11" IPR008518:FATE/Miff/Tango-11 CG30404 11-Aug-17 DroID_v2017_08 "Drer\mff, Drer\zgc:110130" - "Cele\F11C1.7, Cele\mff-2" Xtro\mff Mmus\Mff Hsap\MFF "developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,viable,visible" "trichogen cell,tormogen cell" FBgn0003327 scal scabrous-like http://flybase.org/reports/FBgn0003327 - gene - - - scal - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,female sterile,reduced" "eye,abdomen & macrochaeta,scutellar bristle,wing,wing vein L2,posterior crossvein" FBgn0003273 Rp21 Ribosomal protein 21 http://flybase.org/reports/FBgn0003273 - gene structural constituent of ribosome ; GO:0003735 | non-traceable author statement translation ; GO:0006412 | non-traceable author statement ribosome ; GO:0005840 | non-traceable author statement "rp21, Rp21" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264299 CG43777 - http://flybase.org/reports/FBgn0264299 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG43777, CG13569, CG13569-3" "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG43777 11-Aug-17 DroID_v2017_08 "Drer\crispld2, Drer\pi15a, Drer\r3hdml, Drer\crispld1a, Drer\pi15b, Drer\glipr1b, Drer\crispld1b, Drer\LOC100536500, Drer\glipr2, Drer\glipr2l" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\lon-1, Cele\scl-23" "Xtro\crisp2, Xtro\crisp1, Xtro\crisp3, Xtro\r3hdml, Xtro\crispld2, Xtro\MGC108118, Xtro\glipr2" "Mmus\Glipr1, Mmus\Pi16, Mmus\Crispld1, Mmus\Crisp4, Mmus\Glipr2, Mmus\Crisp2, Mmus\Crisp3, Mmus\Crisp1, Mmus\Glipr1l2, Mmus\Glipr1l1, Mmus\R3hdml, Mmus\Crispld2, Mmus\Clec18a, Mmus\Pi15" "Hsap\GLIPR1, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\CRISP2, Hsap\GLIPR2, Hsap\CRISP1, Hsap\CRISPLD1, Hsap\PI16, Hsap\CLEC18A, Hsap\R3HDML, Hsap\GLIPR1L1, Hsap\CLEC18B, Hsap\CLEC18C, Hsap\PI15" viable FBgn0086053 snoRNA:Me18S-G1358a - http://flybase.org/reports/FBgn0086053 snoRNA_gene - - - "snoRNA:Me18S-G1358a, Me18S-Gm1358a, Me18S-G1358a, CR34682" - CR34682 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260276 GSd211 - http://flybase.org/reports/FBgn0260276 gene - - - GSd211 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0041120 l(2)cl-L3 lethal (2) cell lethal L3 http://flybase.org/reports/FBgn0041120 gene - - - "cl2L3, l(2)cl-L3" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053701 CR33701 - http://flybase.org/reports/FBgn0053701 pseudogene_attribute - - - CR33701 - CR33701 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066354 l(3)99DEa lethal (3) 99DEa http://flybase.org/reports/FBgn0066354 gene - - - l(3)99DEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010522 l(2)02836a lethal (2) 02836a http://flybase.org/reports/FBgn0010522 - gene - - - "l(2)02836, l(2)02836a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021979 l(2)k09913 lethal (2) k09913 http://flybase.org/reports/FBgn0021979 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3082, l(2)k09913, 1(2)k09913" "IPR008547:Protein of unknown function DUF829, TMEM53, IPR029058:Alpha/Beta hydrolase fold" CG3082 11-Aug-17 DroID_v2017_08 "Drer\tmem53, Drer\si:dkey-5i3.5" - - "Xtro\LOC100486876, Xtro\tmem53" Mmus\Tmem53 Hsap\TMEM53 "lethal,recessive" FBgn0000793 fs(1)de3 female sterile (1) defective eggs 3 http://flybase.org/reports/FBgn0000793 - gene - - - "de3, fs(1)de3" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "endochorion,dorsal appendage,chorion" FBgn0065105 snmRNA:157 small non-messenger RNA 157 http://flybase.org/reports/FBgn0065105 non_protein_coding_gene - - - "Dm-157, CR33707, snmRNA:157" - CR33707 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261717 DJ1026 - http://flybase.org/reports/FBgn0261717 gene - - - DJ1026 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038733 CG11407 - http://flybase.org/reports/FBgn0038733 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 bioluminescence ; GO:0008218 | inferred from electronic annotation with InterPro:IPR027380 sleep ; GO:0030431 | inferred from expression pattern - CG11407 "IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site, IPR027380:Luciferase, N-terminal domain, IPR025110:AMP-binding enzyme C-terminal domain" CG11407 11-Aug-17 DroID_v2017_08 Drer\acsf3 Scer\PCS60 "Cele\acs-1, Cele\acs-2, Cele\acs-7, Cele\acs-16, Cele\mec-18, Cele\C32E8.6, Cele\acs-9" Xtro\acsf3 Mmus\Acsf3 "Hsap\ACSF3, Hsap\ACSF2" viable FBgn0267169 CR45609 - http://flybase.org/reports/FBgn0267169 non_protein_coding_gene - - - CR45609 - CR45609 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014107 anon-4Cf anon-4Cf http://flybase.org/reports/FBgn0014107 - gene - - - "T16, anon-4Cf" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034436 CG11961 - http://flybase.org/reports/FBgn0034436 protein_coding_gene - - - "CG11961, CG11961-PA" IPR007484:Peptidase M28 CG11961 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\APE3, Scer\VPS70, Scer\PFF1, Scer\YDR415C" "Cele\C44B7.11, Cele\B0495.7" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0263510 nclb no child left behind http://flybase.org/reports/FBgn0263510 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | NOT inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype male gonad development ; GO:0008584 | inferred from mutant phenotype transcriptionally active chromatin ; GO:0035327 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "nclb, CG6751" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like" CG6751 11-Aug-17 DroID_v2017_08 Drer\pwp1 Scer\PWP1 "Cele\JC8.2, Cele\Y32H12A.8" Xtro\pwp1 Mmus\Pwp1 Hsap\PWP1 FBgn0003238 rapid-exhaustion rapid exhaustion http://flybase.org/reports/FBgn0003238 - gene - - - "rex, rapid-exhaustion" - - 11-Aug-17 DroID_v2017_08 - - - - - - "bang sensitive,lethal,heat sensitive,uncoordinated,neurophysiology defective" FBgn0026338 Su(tor)2-280-28 Su(tor)2-280-28 http://flybase.org/reports/FBgn0026338 - gene - - - Su(tor)2-280-28 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040581 CG15496 - http://flybase.org/reports/FBgn0040581 protein_coding_gene - - - CG15496 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031364 CG17648 - http://flybase.org/reports/FBgn0031364 protein_coding_gene - - - "BcDNA:GH02930, CG17648" - CG17648 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0041121 l(2)45Bf lethal (2) 45Bf http://flybase.org/reports/FBgn0041121 gene - - - l(2)45Bf - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031494 CG17219 - http://flybase.org/reports/FBgn0031494 protein_coding_gene S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from sequence or structural similarity with SGD:S000001372 biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000001372 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000001372 CG17219 "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR019410:Lysine methyltransferase" CG17219 11-Aug-17 DroID_v2017_08 Drer\si:dkey-15f17.8 "Scer\NNT1, Scer\HPM1" "Cele\F22B7.9, Cele\K01A11.2" Xtro\mettl18 Mmus\Mettl18 Hsap\METTL18 viable FBgn0016835 l(1)MZ3 lethal (1) MZ3 http://flybase.org/reports/FBgn0016835 - gene - - - "l(1)MZ3, M3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003361 sesD stress-sensitive D http://flybase.org/reports/FBgn0003361 - gene - - - sesD - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044027 Ori66Dbeta Ori66Dbeta http://flybase.org/reports/FBgn0044027 origin_of_replication - - - "ori-beta, Ori-beta, Ori66Dbeta, Oribeta" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259636 B0339 - http://flybase.org/reports/FBgn0259636 gene - - - B0339 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0262420 mir-318 mir-318 stem loop http://flybase.org/reports/FBgn0262420 miRNA_gene - eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype - "dme-mir-318, miR-318, mir-318, CR42971, Mir-318, CR33622" - CR42971 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing vein" FBgn0027497 Madm MLF1-adaptor molecule http://flybase.org/reports/FBgn0027497 FBgn0062034 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with UniProtKB:Q99J45 intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with UniProtKB:Q9UHY1 protein secretion ; GO:0009306 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000357046 protein phosphorylation ; GO:0006468 | NOT inferred from key residues regulation of cell size ; GO:0008361 | inferred from direct assay regulation of cell proliferation ; GO:0042127 | inferred from direct assay intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000357044 endomembrane system ; GO:0012505 | inferred from sequence or structural similarity with UniProtKB:Q9UHY1 Golgi apparatus ; GO:0005794 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG1098, dMADM, BcDNA:LD28657, anon-WO0118547.406, Madm, MADM, lincRNA.S6031, MadM" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG1098 11-Aug-17 DroID_v2017_08 "Drer\nrbp2a, Drer\nrbp2b, Drer\nrbp1, Drer\zmp:0000000943" "Scer\SSK2, Scer\CDC5" Cele\hpo-11 Xtro\nrbp1 "Mmus\Nrbp2, Mmus\Nrbp1" "Hsap\NRBP2, Hsap\NRBP1" "viable,visible,developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,partially lethal - majority die" "trichogen cell,head,eye,cell autonomous,somatic clone,ommatidium,rhabdomere | cell autonomous | somatic clone,photoreceptor cell" DRSC25999 K 0.815387428 -0.146710175 -0.063836704 -1.001902379 -0.268540573 1.646136044 FBgn0014909 anon-4Fc anon-4Fc http://flybase.org/reports/FBgn0014909 - gene - - - anon-4Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040744 CG12711 - http://flybase.org/reports/FBgn0040744 protein_coding_gene - - - CG12711 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031441 CG9962 - http://flybase.org/reports/FBgn0031441 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966" Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 phagocytosis ; GO:0006909 | inferred from biological aspect of ancestor with PANTHER:PTN000225967 protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 CG9962 "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG9962 11-Aug-17 DroID_v2017_08 Drer\csnk1a1 "Scer\YCK3, Scer\YCK1, Scer\YCK2, Scer\HRR25" "Cele\K09E4.1, Cele\kin-19, Cele\W09C3.1, Cele\F26A1.4, Cele\M04F3.3, Cele\Y111B2A.27" Xtro\csnk1a1 "Mmus\Vrk2, Mmus\Csnk1a1" "Hsap\CSNK1A1, Hsap\VRK2, Hsap\CSNK1A1L" viable FBgn0015616 Cazip1 Caz-interacting protein 1 http://flybase.org/reports/FBgn0015616 - gene - - - Cazip1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039494 grass Gram-positive Specific Serine protease http://flybase.org/reports/FBgn0039494 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 innate immune response ; GO:0045087 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype defense response ; GO:0006952 | inferred from mutant phenotype inferred from genetic interaction with psh proteolysis ; GO:0006508 | inferred from sequence model" extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | inferred by curator from GO:0050830 "grass, CG5896, c-SP1, SP1, SP2, Grass" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG5896 11-Aug-17 DroID_v2017_08 "Drer\prss60.1, Drer\prss60.2, Drer\prss60.3" - Cele\try-3 - - - "immune response defective,viable,recessive" FBgn0053429 5SrRNA:CR33429 5SrRNA:CR33429 http://flybase.org/reports/FBgn0053429 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33429, 5SrRNA:CR33429" - CR33429 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036906 CG14102 - http://flybase.org/reports/FBgn0036906 protein_coding_gene - - - CG14102 "IPR032675:Leucine-rich repeat domain, L domain-like" CG14102 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0019653 sng snaggle http://flybase.org/reports/FBgn0019653 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available sng - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015443 l(1)7DEa lethal (1) 7DEa http://flybase.org/reports/FBgn0015443 - gene - - - l(1)7DEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053725 CG33725 - http://flybase.org/reports/FBgn0053725 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33725 IPR010512:Protein of unknown function DUF1091 CG33725 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264892 CR44083 - http://flybase.org/reports/FBgn0264892 non_protein_coding_gene - - - CR44083 - CR44083 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086668 snoRNA:Psi28S-3436a snoRNA:Psi28S-3436a http://flybase.org/reports/FBgn0086668 snoRNA_gene - - - "snoRNA:708, psi28S-3436a, Dm-708, snoR708, CR33751, Psi 28S-3436a(SnoR708), Psi28S-3436a, snoRNA:Psi28S-3436a" - CR33751 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060875 l(3)S045822 lethal (3) S045822 http://flybase.org/reports/FBgn0060875 gene - - - "0458/22, l(3)S045822" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0060805 l(3)S056003b lethal (3) S056003b http://flybase.org/reports/FBgn0060805 gene - - - "0560/03, l(3)S056003b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal" FBgn0001920 l(2)25Ca lethal (2) 25Ca http://flybase.org/reports/FBgn0001920 - gene - - - "DTS, l(2)2[DTS], l(2)DCS, l(2)25AD, l(2)25Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,cold sensitive,heat sensitive,recessive" FBgn0041113 l(3)cl-L5 lethal (3) cell lethal L5 http://flybase.org/reports/FBgn0041113 gene - - - "cl3L5, l(3)cl-L5" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0021771 ms(3)P50 ms(3)P50 http://flybase.org/reports/FBgn0021771 - gene - - - ms(3)P50 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0015459 l(2)37CDd lethal (2) 37CDd http://flybase.org/reports/FBgn0015459 - gene - - - "l(2)E2, l(2)37CDd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051233 CG31233 - http://flybase.org/reports/FBgn0051233 protein_coding_gene metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR014782 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR014782 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001930 - "CG5839, anon-WO0140519.65, anon-WO0140519.125, CG31233" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG31233 11-Aug-17 DroID_v2017_08 "Drer\anpepb, Drer\erap2, Drer\ctrl, Drer\enpep, Drer\erap1b, Drer\erap1a, Drer\si:ch211-198g19.1, Drer\npepps, Drer\anpepa, Drer\si:ch211-106j24.1, Drer\si:ch211-149p5.1, Drer\lnpep, Drer\si:ch211-276a23.5" "Scer\AAP1, Scer\APE2, Scer\TMA108" "Cele\Y67D8C.9, Cele\pam-1, Cele\T12E12.6, Cele\T07F10.1" "Xtro\lvrn, Xtro\anpep, Xtro\erap1, Xtro\lnpep, Xtro\enpep, Xtro\npepps" "Mmus\Lnpep, Mmus\Erap1, Mmus\Npepps, Mmus\Anpep, Mmus\Enpep, Mmus\Lvrn, Mmus\Trhde" "Hsap\LNPEP, Hsap\LVRN, Hsap\ENPEP, Hsap\ERAP1, Hsap\ANPEP, Hsap\ERAP2, Hsap\NPEPPS, Hsap\TRHDE" FBgn0038402 Fer2 48 related 2 http://flybase.org/reports/FBgn0038402 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype negative regulation of oxidative stress-induced neuron death ; GO:1903204 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype generation of neurons ; GO:0048699 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with twi" - "CG5952, Fer2, bHLHa33, fer2" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG5952 11-Aug-17 DroID_v2017_08 "Drer\ptf1a, Drer\atoh1c, Drer\si:ch211-246m6.4, Drer\scxa, Drer\bhlha9, Drer\scxb, Drer\nhlh2, Drer\tcf15" - "Cele\hlh-12, Cele\hlh-15, Cele\lin-32, Cele\hlh-3, Cele\hlh-13" "Xtro\ptf1a, Xtro\nhlh1, Xtro\scx, Xtro\tcf15, Xtro\ferd3l" "Mmus\Scx, Mmus\Ascl5, Mmus\Tcf15, Mmus\Bhlha9, Mmus\Ptf1a, Mmus\Ferd3l" "Hsap\FERD3L, Hsap\TWIST1, Hsap\NHLH2, Hsap\SCX, Hsap\ASCL5, Hsap\TCF15, Hsap\BHLHA9, Hsap\PTF1A" "viable,fertile,locomotor rhythm defective" "l-LNv neuron,s-LNv neuron,LNd neuron" FBgn0005041 E(var)25F Enhancer of variegation 25F http://flybase.org/reports/FBgn0005041 - gene - - - "E-var, E(var)25F" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040918 schlank schlank http://flybase.org/reports/FBgn0040918 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR009057 sphingosine N-acyltransferase activity ; GO:0050291 | inferred from sequence or structural similarity with MGI:MGI:1919199,MGI:MGI:2442564 inferred from direct assay" negative regulation of lipid catabolic process ; GO:0050995 | inferred from mutant phenotype positive regulation of lipid biosynthetic process ; GO:0046889 | inferred from mutant phenotype SREBP signaling pathway ; GO:0032933 | inferred from mutant phenotype triglyceride metabolic process ; GO:0006641 | inferred from mutant phenotype ceramide biosynthetic process ; GO:0046513 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006634, InterPro:IPR016439 integral component of membrane ; GO:0016021 | inferred from sequence model endoplasmic reticulum ; GO:0005783 | inferred from direct assay nuclear inner membrane ; GO:0005637 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay" "Dlag1, CG3576, lon, DLAG1, l(1)G0061, l(1)G0365, l(1)G0489, CG15898, DLag1, lag1, Lag1, schlank, CerS" "IPR001356:Homeobox domain, IPR006634:TRAM/LAG1/CLN8 homology domain, IPR009057:Homeobox domain-like, IPR016439:Ceramide synthase component Lag1/Lac1" CG3576 11-Aug-17 DroID_v2017_08 "Drer\cers3a, Drer\cers2b, Drer\cers1, Drer\cers5, Drer\cers4a, Drer\cers3b, Drer\cers4b, Drer\cers2a, Drer\cers6" "Scer\LAG1, Scer\LAC1" "Cele\hyl-2, Cele\hyl-1" "Xtro\cers3, Xtro\cers6, Xtro\cers1, Xtro\cers2, Xtro\cers5" "Mmus\Cers2, Mmus\Cers5, Mmus\Cers4, Mmus\Cers1, Mmus\Cers6, Mmus\Cers3" "Hsap\CERS5, Hsap\CERS3, Hsap\CERS4, Hsap\CERS2, Hsap\CERS1, Hsap\CERS6" "lethal - all die before end of larval stage,some die during larval stage,small body,developmental rate defective,female sterile germline-dependent,germline clone,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,viable,visible" trichogen cell DRSC18313 I 1.56525998 1.25747468 0.513895389 0.738167338 -0.656069603 -1.1335483 FBgn0016907 l(3)X2 lethal (3) X2 http://flybase.org/reports/FBgn0016907 - gene - - - "X2, l(3)X2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267706 CR46039 - http://flybase.org/reports/FBgn0267706 non_protein_coding_gene - - - CR46039 - CR46039 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082983 snoRNA:Psi28S-2626 snoRNA:Psi28S-2626 http://flybase.org/reports/FBgn0082983 snoRNA_gene - - - "snoRNA:Psi28S-2626, Psi28S-2626, psi28S-2626, Psi 28S-2626, CR34629, chr3R:26033540..26033785" - CR34629 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042685 Tirant\pol Tirant element pol http://flybase.org/reports/FBgn0042685 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "ORF2, Tirant\pol, pol" "IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259574 B2017 - http://flybase.org/reports/FBgn0259574 gene - - - B2017 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,partially,some die during pupal stage" "leg,unguis,arista,proboscis" FBgn0029098 anon-89Be anon-89Be http://flybase.org/reports/FBgn0029098 gene - - - anon-89Be - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029892 CG3184 - http://flybase.org/reports/FBgn0029892 protein_coding_gene demethylase activity ; GO:0032451 | inferred from sequence or structural similarity with SGD:S000000450 peptidyl-diphthamide biosynthetic process from peptidyl-histidine ; GO:0017183 | inferred from sequence or structural similarity with SGD:S000000450 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000450 CG3184 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain" CG3184 11-Aug-17 DroID_v2017_08 Drer\dph7 "Scer\RRT2, Scer\MTC5" "Cele\Y43F4B.9, Cele\wdr-23" Xtro\dph7 Mmus\Dph7 Hsap\DPH7 viable FBgn0014933 anon-87Eb anon-87Eb http://flybase.org/reports/FBgn0014933 - gene - - - "B, anon-87Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060610 l(3)S090308 lethal (3) S090308 http://flybase.org/reports/FBgn0060610 gene - - - "0903/08, l(3)S090308" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0025341 anon-58Fb anon-58Fb http://flybase.org/reports/FBgn0025341 - gene - - - "12.2, anon-58Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020257 Ppa Partner of paired http://flybase.org/reports/FBgn0020257 FBgn0034764 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | non-traceable author statement SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG9952, Ppa, I-55, ppa, FBXL14, PPA" "IPR001810:F-box domain, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR006553:Leucine-rich repeat, cysteine-containing subtype" CG9952 11-Aug-17 DroID_v2017_08 "Drer\fbxl14b, Drer\fbxl14a" "Scer\RAD7, Scer\GRR1, Scer\AMN1" "Cele\C04E6.5, Cele\duo-1" Xtro\fbxl14 Mmus\Fbxl14 Hsap\FBXL14 "chemical sensitive,viable,visible,body color defective" mesothoracic tergum FBgn0267299 CR45735 - http://flybase.org/reports/FBgn0267299 non_protein_coding_gene - - - CR45735 - CR45735 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038000 CG10014 - http://flybase.org/reports/FBgn0038000 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10014 "IPR000048:IQ motif, EF-hand binding site, IPR003117:cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain" CG10014 11-Aug-17 DroID_v2017_08 Drer\ropn1l - Cele\K08D12.6 - "Mmus\Ropn1, Mmus\Iqce, Mmus\Ropn1l" "Hsap\SPA17, Hsap\ROPN1L, Hsap\ROPN1B, Hsap\ROPN1" viable FBgn0263093 CR43361 - http://flybase.org/reports/FBgn0263093 pseudogene_attribute - - - "CR43361, CG32021" - CR43361 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011626 l(2)T56j5 lethal (2) T56j5 http://flybase.org/reports/FBgn0011626 FBgn0005177 gene - - - l(2)T56j5 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259838 Su(Ste):CR42407 Su(Ste):CR42407 http://flybase.org/reports/FBgn0259838 non_protein_coding_gene - - - "Su(Ste):CR42407, RR42201, CR42407" - CR42407 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263534 mir-4960 mir-4960 stem loop http://flybase.org/reports/FBgn0263534 miRNA_gene - - - "mir-4960, dme-mir-4960, CR43519" - CR43519 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061115 l(3)S005515b lethal (3) S005515b http://flybase.org/reports/FBgn0061115 gene - - - "0055/15, l(3)S005515b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045977 PdL35B1 PdL35B1 http://flybase.org/reports/FBgn0045977 gene - - - PdL35B1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,short lived,lethal,recessive" wing FBgn0266278 CR44963 - http://flybase.org/reports/FBgn0266278 non_protein_coding_gene - - - CR44963 - CR44963 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065853 l(2)SH0301 lethal (2) SH0301 http://flybase.org/reports/FBgn0065853 gene - - - "l(2)SH0301, l(2)SH2 0301" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036536 CG12713 - http://flybase.org/reports/FBgn0036536 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12713 IPR029404:Protein of unknown function with TPD sequence-motif CG12713 11-Aug-17 DroID_v2017_08 Drer\zgc:154061 - - Xtro\c15orf41 Mmus\BC052040 Hsap\C15orf41 "viable,visible" trichogen cell FBgn0082668 GS3132 GS3132 http://flybase.org/reports/FBgn0082668 gene - - - GS3132 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0266222 CR44917 - http://flybase.org/reports/FBgn0266222 non_protein_coding_gene - - - CR44917 - CR44917 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259633 B0319 - http://flybase.org/reports/FBgn0259633 gene - - - B0319 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible 1st posterior cell FBgn0025174 l(2)38Db lethal (2) 38Db http://flybase.org/reports/FBgn0025174 - gene - - - l(2)38Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265823 CR44612 - http://flybase.org/reports/FBgn0265823 non_protein_coding_gene - - - CR44612 - CR44612 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045062 fs(1)100 female sterile (1) 100 http://flybase.org/reports/FBgn0045062 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)100 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "nurse cell,supernumerary,nurse cell ring canal" FBgn0032660 elfless elfless http://flybase.org/reports/FBgn0032660 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000548413 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000548413 negative regulation of protein sumoylation ; GO:0033234 | inferred from biological aspect of ancestor with PANTHER:PTN001495439 protein ubiquitination ; GO:0016567 | inferred from biological aspect of ancestor with PANTHER:PTN000548413 nucleus ; GO:0005634 | inferred from direct assay SUMO-targeted ubiquitin ligase complex ; GO:0033768 | inferred from biological aspect of ancestor with PANTHER:PTN001495439 "CG15150, BcDNA:AT24563, elfless" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15150 11-Aug-17 DroID_v2017_08 "Drer\ftr70, Drer\trim35-34, Drer\trim35-31, Drer\LOC100536643, Drer\si:ch73-106l15.2, Drer\trim35-24, Drer\trim35-30, Drer\trim35-35, Drer\trim35-9, Drer\trim35-20, Drer\rnf4, Drer\trim35-28, Drer\trim35-19, Drer\si:ch1073-324l1.1, Drer\si:ch73-106l15.3, Drer\si:ch73-166o21.1, Drer\si:ch211-175l6.2, Drer\trim35-13, Drer\trim35-1, Drer\trim35-25, Drer\si:ch211-12p12.2, Drer\trim35-12, Drer\trim35-33, Drer\trim35-29, Drer\trim35-23, Drer\trim35-14, Drer\trim35-10, Drer\rnf222, Drer\trim35-7, Drer\trim35-3" Scer\SLX8 "Cele\Y38C1AA.6, Cele\T02C1.1, Cele\T01G5.7, Cele\C28G1.6" "Xtro\trim69.2, Xtro\rnf4" "Mmus\Rnf125, Mmus\Trim7, Mmus\Trim35, Mmus\Trim10, Mmus\Trim26, Mmus\Rnf4, Mmus\Rnf222" "Hsap\TRIM26, Hsap\RNF4, Hsap\TRIM7, Hsap\TRIM35, Hsap\RNF125, Hsap\RNF222, Hsap\TRIM10" "viable,visible,eye color defective,lethal,fertile" "pigment cell,interommatidial bristle,eye" FBgn0024558 Dph5 Diphthamide methyltransferase http://flybase.org/reports/FBgn0024558 "FBgn0027877, FBgn0051289" protein_coding_gene diphthine synthase activity ; GO:0004164 | inferred from sequence or structural similarity diphthine synthase activity ; GO:0004164 | inferred from sequence or structural similarity with SGD:S000004162 peptidyl-diphthamide biosynthetic process from peptidyl-histidine ; GO:0017183 | inferred from sequence or structural similarity with SGD:S000004162 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000004162 "CG5275, l(3)L4910, BcDNA.LD12153, CG31289, BcDNA:LD12153, Dph5" "IPR000878:Tetrapyrrole methylase, IPR004551:Diphthine synthase, IPR014776:Tetrapyrrole methylase, subdomain 2, IPR014777:Tetrapyrrole methylase, subdomain 1" CG31289 11-Aug-17 DroID_v2017_08 Drer\dph5 Scer\DPH5 Cele\B0491.7 Xtro\dph5 Mmus\Dph5 Hsap\DPH5 "lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0030859 CG12990 - http://flybase.org/reports/FBgn0030859 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG12990 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG12990 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-54, Cele\oac-5, Cele\oac-53, Cele\oac-9, Cele\oac-39, Cele\oac-20, Cele\ndg-4, Cele\oac-55, Cele\rhy-1, Cele\nrf-6, Cele\oac-3, Cele\oac-31, Cele\oac-32, Cele\oac-50, Cele\oac-6, Cele\oac-46, Cele\oac-7, Cele\oac-14" - Mmus\Oacyl - viable FBgn0004930 a(1)48 abnormal abdomen (1) 48 http://flybase.org/reports/FBgn0004930 - gene - - - a(1)48 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,good,fertile,maternal effect" "abdomen,adult abdomen" FBgn0267737 CR46068 - http://flybase.org/reports/FBgn0267737 non_protein_coding_gene - - - "CR46068, Mgn1712" - CR46068 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050280 CG30280 - http://flybase.org/reports/FBgn0050280 protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from sequence or structural similarity with HGNC:3623 chitin binding ; GO:0008061 | inferred from sequence or structural similarity with HGNC:25922 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with HGNC:3623 membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:25922 "CG6676, CG30280, AAF46801, FBpp0071673" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR020837:Fibrinogen, conserved site, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG30280 11-Aug-17 DroID_v2017_08 "Drer\angpt4, Drer\fgb, Drer\zmp:0000000846, Drer\wu:fj11g02, Drer\si:ch1073-110a20.2, Drer\fibcd1, Drer\fgl1, Drer\si:ch1073-110a20.3, Drer\angptl5, Drer\si:ch211-157b11.8, Drer\tnc, Drer\angptl2b, Drer\angpt1, Drer\fga, Drer\LOC100007488, Drer\si:ch211-287a12.9, Drer\zgc:173915, Drer\si:ch1073-110a20.1, Drer\si:dkeyp-51b7.3, Drer\tnw, Drer\fgg, Drer\angptl1a, Drer\angptl4, Drer\mfap4, Drer\angptl2a, Drer\angptl7, Drer\fgl2a, Drer\tnr, Drer\angptl6, Drer\si:zfos-2330d3.8, Drer\si:ch211-203k16.3, Drer\tnxba, Drer\angpt2a, Drer\angptl3, Drer\si:zfos-2330d3.6, Drer\si:zfos-2330d3.1, Drer\zgc:194887, Drer\fgl2b, Drer\angpt2b, Drer\LOC555374, Drer\si:zfos-2330d3.3, Drer\zgc:171687" Scer\SMC1 "Cele\Y43C5A.2, Cele\W05B2.2, Cele\C49C8.5, Cele\ensh-1, Cele\ZC504.1, Cele\T15B7.1, Cele\Y69H2.3, Cele\Y26D4A.12, Cele\C08G9.2, Cele\K10D3.4, Cele\Y69H2.10" "Xtro\angpt1, Xtro\fgl1, Xtro\tnc, Xtro\fcn3, Xtro\tnxb, Xtro\fgg, Xtro\angptl7, Xtro\angptl4, Xtro\angptl5, Xtro\tnr, Xtro\angptl3, Xtro\LOC100491105, Xtro\angpt4, Xtro\fcn1, Xtro\fga, Xtro\LOC100488177, Xtro\tnn, Xtro\mfap4, Xtro\LOC100497330, Xtro\fcn2, Xtro\fibcd1, Xtro\fgl2, Xtro\angptl2, Xtro\fgb" "Mmus\Angptl3, Mmus\Fcna, Mmus\Fgb, Mmus\Mfap4, Mmus\Angpt2, Mmus\Fibcd1, Mmus\Fgl1, Mmus\Tnc, Mmus\Fga, Mmus\Angptl4, Mmus\Angptl6, Mmus\Angpt1, Mmus\Angptl1, Mmus\Angpt4, Mmus\Fgl2, Mmus\Angptl2, Mmus\Fcnb, Mmus\Tnn, Mmus\Fgg, Mmus\Tnr, Mmus\Angptl7, Mmus\Tnxb" "Hsap\TNXB, Hsap\FGG, Hsap\ANGPTL3, Hsap\FGB, Hsap\TNC, Hsap\TNR, Hsap\MFAP4, Hsap\ANGPTL1, Hsap\FIBCD1, Hsap\FGA, Hsap\FGL2, Hsap\ANGPT4, Hsap\ANGPT1, Hsap\TNN, Hsap\ANGPTL4, Hsap\ANGPTL2, Hsap\FGL1, Hsap\FCN3, Hsap\ANGPT2, Hsap\ANGPTL6, Hsap\FCN2, Hsap\FCN1, Hsap\ANGPTL7, Hsap\ANGPTL5" "viable,visible" "chaeta,supernumerary" FBgn0030505 NFAT NFAT nuclear factor http://flybase.org/reports/FBgn0030505 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR008366, InterPro:IPR008967, InterPro:IPR011539 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR011539" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR008366, InterPro:IPR008967, InterPro:IPR011539 regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok response to salt stress ; GO:0009651 | inferred from mutant phenotype negative regulation of synaptic vesicle exocytosis ; GO:2000301 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr" - "NFAT, CG11172, NF-AT5, EP1335, NFAT5, dNFAT, MESR1, Nfat" "IPR002909:IPT domain, IPR008366:Nuclear factor of activated T cells (NFAT), IPR008967:p53-like transcription factor, DNA-binding, IPR011539:Rel homology domain (RHD), DNA-binding domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011990:Tetratricopeptide-like helical domain, IPR032397:Rel homology dimerisation domain" CG11172 11-Aug-17 DroID_v2017_08 "Drer\LOC571865, Drer\nfatc4, Drer\nfatc3b, Drer\nfatc3a, Drer\nfat5b, Drer\nfatc1, Drer\nfatc2a, Drer\nfat5a" - "Cele\F53A2.3, Cele\Y75B12A.2, Cele\Y66D12A.1, Cele\AH10.2, Cele\Y50E8A.11" "Xtro\nfatc4, Xtro\nfatc3, Xtro\nfatc1, Xtro\nfat5, Xtro\nfatc2" "Mmus\Nfat5, Mmus\Nfatc3, Mmus\Nfatc1, Mmus\Nfatc2, Mmus\Nfatc4" "Hsap\NFATC2, Hsap\NFATC4, Hsap\NFATC3, Hsap\NFATC1, Hsap\NFAT5" "viable,fertile,neuroanatomy defective,visible,neurophysiology defective,locomotor rhythm defective,lethal,recessive,partially lethal - majority live,wild-type,osmotic stress response defective" "intersegmental nerve,anterior fascicle & synapse,eye,wing vein,synapse,NMJ bouton,synapseD42,RP neuron,neuromuscular junctionRapGAP1-OK6,dorsocentral bristle,scutellar bristle,trichogen cell,neuromuscular junction,supernumerary,neuromuscular junctionD42,RP2 motor neuron,pupa,embryonic/larval anal pad" FBgn0264260 CG43760 - http://flybase.org/reports/FBgn0264260 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43760 - CG43760 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051532 CG31532 - http://flybase.org/reports/FBgn0051532 protein_coding_gene - - - CG31532 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065223 l(2)SH2221 lethal (2) SH2221 http://flybase.org/reports/FBgn0065223 gene - - - "l(2)SH2221, l(2)SH2 2221" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266028 CR44793 - http://flybase.org/reports/FBgn0266028 non_protein_coding_gene - - - CR44793 - CR44793 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001796 l(1)Mb38 lethal (1) Mb38 http://flybase.org/reports/FBgn0001796 - gene - - - l(1)Mb38 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" male genitalia FBgn0266239 CR44934 - http://flybase.org/reports/FBgn0266239 non_protein_coding_gene - - - "CR44934, lincRNA.711" - CR44934 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024708 anon-83Ba anon-83Ba http://flybase.org/reports/FBgn0024708 - gene - - - anon-83Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050392 CG30392 - http://flybase.org/reports/FBgn0050392 protein_coding_gene glycolipid transporter activity ; GO:0017089 | inferred from electronic annotation with InterPro:IPR014830 glycolipid binding ; GO:0051861 | inferred from electronic annotation with InterPro:IPR014830 glycolipid transport ; GO:0046836 | inferred from electronic annotation with InterPro:IPR014830 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR014830 "CG10509, anon-WO0153538.80, CG30392" IPR014830:Glycolipid transfer protein domain CG30392 11-Aug-17 DroID_v2017_08 "Drer\gltpd2, Drer\cptp, Drer\si:ch73-269m23.5" - "Cele\tag-296, Cele\K08E4.2, Cele\F49D11.10" "Xtro\cptp, Xtro\gltpd2" "Mmus\Gltpd2, Mmus\Cptp" "Hsap\GLTPD2, Hsap\CPTP" "viable,fertile" FBgn0061095 l(3)S009919 lethal (3) S009919 http://flybase.org/reports/FBgn0061095 gene - - - "0099/19, l(3)S009919" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0000682 flrdE flight reduced E http://flybase.org/reports/FBgn0000682 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdE - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0040005 CG17883 - http://flybase.org/reports/FBgn0040005 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000467547 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000467547 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000467547 endoplasmic reticulum ; GO:0005783 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000467547 "CG40289, CG17883" IPR000195:Rab-GTPase-TBC domain CG17883 11-Aug-17 DroID_v2017_08 "Drer\tbc1d20, Drer\zgc:63863" Scer\GYP8 Cele\tbc-20 Xtro\tbc1d20.1 Mmus\Tbc1d20 Hsap\TBC1D20 viable FBgn0259568 B1187 - http://flybase.org/reports/FBgn0259568 gene - - - B1187 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0065207 l(2)SH2275 lethal (2) SH2275 http://flybase.org/reports/FBgn0065207 gene - - - "l(2)SH2275, SH2275" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266045 CR44810 - http://flybase.org/reports/FBgn0266045 non_protein_coding_gene - - - "CR44810, lincRNA.388" - CR44810 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032366 CG14930 - http://flybase.org/reports/FBgn0032366 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14930 - CG14930 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038626 CG7691 - http://flybase.org/reports/FBgn0038626 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG7691 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7691 11-Aug-17 DroID_v2017_08 "Drer\snai1b, Drer\scrt1b, Drer\snai1a, Drer\klf17, Drer\snai2, Drer\scrt1a, Drer\hic1, Drer\snai3, Drer\hic1l, Drer\scrt2" - "Cele\scrt-1, Cele\egrh-3, Cele\che-1, Cele\egrh-2, Cele\Y22D7AL.16" "Xtro\snai2, Xtro\snai1" "Mmus\Scrt1, Mmus\Zfp672, Mmus\Snai2, Mmus\Snai1, Mmus\Scrt2, Mmus\Snai3" "Hsap\SCRT1, Hsap\SNAI2, Hsap\SNAI1, Hsap\SNAI3, Hsap\SCRT2" viable FBgn0014248 l(2)60Aa lethal (2) 60Aa http://flybase.org/reports/FBgn0014248 - gene - - - l(2)60Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022004 l(2)k09303 lethal (2) k09303 http://flybase.org/reports/FBgn0022004 - gene - - - l(2)k09303 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050288 CG30288 - http://flybase.org/reports/FBgn0050288 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG30288 "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family, IPR033116:Serine proteases, trypsin family, serine active site" CG30288 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.15, Drer\si:dkey-21e2.7, Drer\masp2, Drer\si:ch211-165b19.5, Drer\tmprss4a, Drer\gzm3, Drer\habp2, Drer\plat, Drer\si:dkey-21e2.12, Drer\si:ch211-165b19.9" - Cele\try-3 - "Mmus\Mcpt1, Mmus\Klk6, Mmus\Plat, Mmus\Mcpt8, Mmus\Gzmg, Mmus\Gzmf, Mmus\Egfbp2, Mmus\Gzmb, Mmus\Gzme, Mmus\Gzmd, Mmus\Mcpt4, Mmus\Klk1b4, Mmus\Gzmc, Mmus\Klk1b9, Mmus\Klk1b5, Mmus\Gzmk, Mmus\Cma1, Mmus\Habp2, Mmus\Tmprss4, Mmus\Cma2, Mmus\Mcpt9, Mmus\Ctsg" "Hsap\PLAT, Hsap\GZMB, Hsap\HABP2, Hsap\GZMK, Hsap\CTSG, Hsap\TMPRSS4, Hsap\KLK14, Hsap\CMA1, Hsap\GZMH" "partially lethal - majority die,some die during pupal stage" FBgn0052344 CG32344 - http://flybase.org/reports/FBgn0052344 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545, InterPro:IPR012541 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR012541 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 helicase activity ; GO:0004386 | inferred from sequence or structural similarity" RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012541 "DmRH20, cg6994, CG6994, CG32344" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR012541:DBP10, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR033517:DDX54/DBP10 family" CG32344 11-Aug-17 DroID_v2017_08 Drer\ddx54 Scer\DBP10 Cele\Y94H6A.5 Xtro\ddx54 Mmus\Ddx54 Hsap\DDX54 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0004653 Fs(1)10A Female sterile (1) 10A http://flybase.org/reports/FBgn0004653 "FBgn0000731, FBgn0001188" gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "hfs, Fs(1)10A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0259386 C38 - http://flybase.org/reports/FBgn0259386 gene - - - C38 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,chaeta" FBgn0005749 l(1)TK302 lethal (1) TK302 http://flybase.org/reports/FBgn0005749 - gene - - - "l302, l(1)TK302" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0082353 HM304 HM304 http://flybase.org/reports/FBgn0082353 gene - - - HM304 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029992 Upf2 Upf2 http://flybase.org/reports/FBgn0029992 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR003890 "gene silencing by miRNA ; GO:0035195 | NOT inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from direct assay neuromuscular synaptic transmission ; GO:0007274 | inferred from direct assay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype RNA interference ; GO:0016246 | NOT inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000303405 exon-exon junction complex ; GO:0035145 | inferred from biological aspect of ancestor with PANTHER:PTN000303405 polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN000303405 "CG2253, UPF2, Upf2, upf2, smg-3" "IPR003890:MIF4G-like, type 3, IPR016024:Armadillo-type fold, IPR007193:Up-frameshift suppressor 2" CG2253 11-Aug-17 DroID_v2017_08 Drer\upf2 Scer\NMD2 Cele\smg-3 Xtro\upf2 Mmus\Upf2 Hsap\UPF2 "lethal,viable,male sterile,fertile,lethal - all die before end of second instar larval stage,male limited,some die during second instar larval stage,germline clone,recessive,semi-fertile,neurophysiology defective,partially lethal - majority die,lethal - all die before end of larval stage,some die during third instar larval stage" "adult tracheal system,somatic clone,eye,dorsal appendage,germline clone,follicle cell" FBgn0024701 bcd::upd1 bcd::os http://flybase.org/reports/FBgn0024701 - engineered_fusion_gene - - - "bcd::os, bcd::upd1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015842 Vm42A Vm42A http://flybase.org/reports/FBgn0015842 - gene - - - "T[[2]], Vm42A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053098 CG33098 - http://flybase.org/reports/FBgn0053098 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "CT39356, BcDNA:AT09395, CG17756, BcDNA:RH08915, CG33098, RLC3" "IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain" CG33098 11-Aug-17 DroID_v2017_08 "Drer\mylpfb, Drer\myl2b, Drer\myl2a, Drer\myl9b, Drer\mylpfa, Drer\myl9a, Drer\myl12.2, Drer\myl7, Drer\myl10, Drer\myl12.1" Scer\MLC2 "Cele\mlc-1, Cele\mlc-2, Cele\mlc-4" "Xtro\myl2, Xtro\myl9, Xtro\mylpf, Xtro\myl7, Xtro\myl10, Xtro\myl12b" "Mmus\Myl10, Mmus\Myl7, Mmus\Myl2, Mmus\Myl12b, Mmus\Myl12a, Mmus\Myl9, Mmus\Mylpf" "Hsap\MYL5, Hsap\MYL12A, Hsap\MYL10, Hsap\MYL7, Hsap\MYL2, Hsap\MYL9, Hsap\MYL12B, Hsap\MYLPF" viable FBgn0038968 CG12499 - http://flybase.org/reports/FBgn0038968 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG12499 "IPR011989:Armadillo-like helical, IPR021714:Nucleolar pre-ribosomal-associated protein 1, N-terminal, IPR032436:Nucleolar pre-ribosomal-associated protein 1, C-terminal domain" CG12499 11-Aug-17 DroID_v2017_08 Drer\urb1 Scer\URB1 Cele\T05H4.10 Xtro\urb1 Mmus\Urb1 Hsap\URB1 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0034129 Parp16 Poly(ADP-ribose) polymerase family member 16 http://flybase.org/reports/FBgn0034129 protein_coding_gene - - - "dPARP16, dARTD15, Parp16, CG15925" - CG15925 11-Aug-17 DroID_v2017_08 "Drer\parp8, Drer\parp16, Drer\parp6b" - - Xtro\parp16 "Mmus\Parp16, Mmus\Parp8, Mmus\Parp6" "Hsap\PARP8, Hsap\PARP6, Hsap\PARP16" viable FBgn0024275 UbxPRE Ultrabithorax Polycomb group response element http://flybase.org/reports/FBgn0024275 - regulatory_region - - - "bxd PRE, PRE, Ubx PRE, Ubx-PRE, UbxPRE, bxdPRE, BXD-PRE, bxd, PRE[[D]], Ubx(PRE)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264530 l(3)ff17 - http://flybase.org/reports/FBgn0264530 gene - - - l(3)ff17 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013990 N52 N52 http://flybase.org/reports/FBgn0013990 - gene - - - N52 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004796 mln muslin http://flybase.org/reports/FBgn0004796 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mln - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0265968 Tfb5 Transcription factor B5 http://flybase.org/reports/FBgn0265968 protein_coding_gene "transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR009400 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from sequence or structural similarity with HGNC:21157 transcriptional open complex formation at RNA polymerase II promoter ; GO:0001113 | inferred from sequence or structural similarity with HGNC:21157 response to UV ; GO:0009411 | inferred from direct assay nucleotide-excision repair ; GO:0006289 | inferred from direct assay" core TFIIH complex ; GO:0000439 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "p8, Dmp8, TTDA, CG14037, TFB5 (uORF), Dromel_CG31917_FBtr0079037_uORF, Tfb5, TFB5, uORF, CG42373, l(2)SH1279, l(2)SH2 1279, lincRNA.843" IPR009400:TFIIH subunit TTDA/Tfb5 CG42373 11-Aug-17 DroID_v2017_08 Drer\gtf2h5 Scer\TFB5 Cele\Y55B1AL.2 Xtro\gtf2h5 Mmus\Gtf2h5 Hsap\GTF2H5 FBgn0030886 CG12672 - http://flybase.org/reports/FBgn0030886 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12672 - CG12672 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025793 Su(var)505 Suppressor of variegation 505 http://flybase.org/reports/FBgn0025793 - gene - - - "Su-var(2)505, Su(var)505" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029821 CG4020 - http://flybase.org/reports/FBgn0029821 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - CG4020 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG4020 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far1, Mmus\Far2" "Hsap\FAR1, Hsap\FAR2" viable FBgn0013347 TfIIA-S Transcription-factor-IIA-S http://flybase.org/reports/FBgn0013347 "FBgn0010326, FBgn0010327, FBgn0063013" protein_coding_gene "RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly ; GO:0001129 | inferred from physical interaction with Tbp RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly ; GO:0001128 | contributes_to inferred from physical interaction with TfIIA-L" transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4647 inferred from sequence or structural similarity with SGD:S000001541 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype transcription factor TFIIA complex ; GO:0005672 | inferred from direct assay transcription factor TFIIA complex ; GO:0005672 | inferred from sequence or structural similarity with HGNC:4647 inferred from sequence or structural similarity with SGD:S000001541 nucleus ; GO:0005634 | inferred from direct assay "dTFIIA-S, TFIIA, CG5163, dTFIIA, TFIIA-S, F121, BcDNA:RE44302, TfIIA-S, tfiia-s, TF-IIAS" "IPR015871:Transcription initiation factor IIA, gamma subunit, C-terminal, IPR015872:Transcription initiation factor IIA, gamma subunit, N-terminal, IPR003194:Transcription initiation factor IIA, gamma subunit, IPR009083:Transcription factor IIA, helical, IPR009088:Transcription factor IIA, beta-barrel" CG5163 11-Aug-17 DroID_v2017_08 Drer\gtf2a2 Scer\TOA2 "Cele\Y111B2A.13, Cele\B0336.13" Xtro\gtf2a2 Mmus\Gtf2a2 Hsap\GTF2A2 "partially lethal - majority die,visible,wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,neuroanatomy defective,some die during pupal stage,female fertile" "eye,photoreceptor cell,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0262418 mir-6-3 mir-6-3 stem loop http://flybase.org/reports/FBgn0262418 miRNA_gene - negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype - "miR-6-3, mir-6-3, mir-6, 6-3, Dme-miR-6, CR42966, miR-6, miR6-3, CR33039, dme-mir-6-3" - CR42966 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | first instar , embryonic stage " viable FBgn0039301 Nup37 Nucleoporin 37kD http://flybase.org/reports/FBgn0039301 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nuclear pore outer ring ; GO:0031080 | inferred from biological aspect of ancestor with PANTHER:PTN000515834 nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with HGNC:29929 "Nup37, CG11875" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG11875 11-Aug-17 DroID_v2017_08 "Drer\mrps2, Drer\nup37" - "Cele\rack-1, Cele\lis-1, Cele\wdr-5.1" "Xtro\nup37, Xtro\mrps2" "Mmus\Nup37, Mmus\Mrps2" "Hsap\NUP37, Hsap\MRPS2" "immune response defective,viable" FBgn0002384 l(3)93Cd lethal (3) 93Cd http://flybase.org/reports/FBgn0002384 - gene - - - "er2, l(3)er2, l(3)93Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0030840 p-cup presidents-cup http://flybase.org/reports/FBgn0030840 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "p-cup, CG12993" IPR011990:Tetratricopeptide-like helical domain CG12993 11-Aug-17 DroID_v2017_08 - - - - - Hsap\TTC25 viable FBgn0011332 l(3)j2C5 lethal (3) j2C5 http://flybase.org/reports/FBgn0011332 - gene - - - l(3)j2C5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259432 EP-J76 - http://flybase.org/reports/FBgn0259432 gene - - - EP-J76 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing hair FBgn0040582 CG5791 - http://flybase.org/reports/FBgn0040582 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model "BcDNA:RH16331, CG5791" - CG5791 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000832 fs(1)M14 female sterile (1) M14 http://flybase.org/reports/FBgn0000832 - gene - - - fs(1)M14 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0053752 CG33752 - http://flybase.org/reports/FBgn0053752 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33752 IPR010512:Protein of unknown function DUF1091 CG33752 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001361 l(1)1EFj lethal (1) 1EFj http://flybase.org/reports/FBgn0001361 - gene - - - "l(1)BA10, l(1)1EFj" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264004 mir-5614 mir-5614 stem loop http://flybase.org/reports/FBgn0264004 gene - - - "mir-5614, CR43747" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052273 tRNA:Met-CAT-2-1 transfer RNA:Methionine-CAT 2-1 http://flybase.org/reports/FBgn0052273 tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "AE002584.trna19-MetCAT, tRNA:M:CAT:AE002584-a, CR32273, chr3L.trna47-MetCAT, tRNA-Met[CAU], tRNA-Met-CAT-2-1, tRNA:Met-CAT-2-1, tRNA:CR32273" - CR32273 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002869 MtnB Metallothionein B http://flybase.org/reports/FBgn0002869 - protein_coding_gene copper ion binding ; GO:0005507 | inferred from direct assay metal ion binding ; GO:0046872 | inferred from direct assay response to metal ion ; GO:0010038 | inferred from direct assay metal ion homeostasis ; GO:0055065 | inferred from mutant phenotype response to metal ion ; GO:0010038 | inferred from sequence or structural similarity with MtnE cellular_component ; GO:0005575 | no biological data available "MTO, MTN, DrosMto, Mto, CG4312, MtnB, mtnB, MtnA" "IPR000966:Metallothionein, family 5, Diptera" CG4312 11-Aug-17 DroID_v2017_08 - "Scer\CUP1-2, Scer\CUP1-1" - - - - FBgn0060429 l(3)S126107 lethal (3) S126107 http://flybase.org/reports/FBgn0060429 gene - - - "1261/07, l(3)S126107" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011256 ms(2)30C male sterile (2) 30C http://flybase.org/reports/FBgn0011256 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(2)07822, ms(2)30C" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" spermatid FBgn0054011 CG34011 - http://flybase.org/reports/FBgn0054011 protein_coding_gene - - - "BP1004, CG34011" - CG34011 11-Aug-17 DroID_v2017_08 "Drer\large, Drer\gxylt1a, Drer\gxylt2, Drer\xxylt1, Drer\gxylt1b, Drer\b4gat1" - - "Xtro\gxylt1, Xtro\gxylt2, Xtro\xxylt1, Xtro\large, Xtro\gyltl1b, Xtro\b4gat1" "Mmus\Gxylt2, Mmus\Large2, Mmus\Large1, Mmus\B4gat1, Mmus\Xxylt1, Mmus\Gxylt1" "Hsap\XXYLT1, Hsap\GXYLT1, Hsap\B4GAT1, Hsap\LARGE2, Hsap\LARGE1, Hsap\GXYLT2" FBgn0004755 l(3)89Bh lethal (3) 89Bh http://flybase.org/reports/FBgn0004755 - gene - - - l(3)89Bh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040200 l(1)G0087 lethal (1) G0087 http://flybase.org/reports/FBgn0040200 gene - - - l(1)G0087 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0267896 CR46184 - http://flybase.org/reports/FBgn0267896 pseudogene_attribute - - - "CR46184, CG12717-related" - CR46184 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040906 CG15579 - http://flybase.org/reports/FBgn0040906 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15579 IPR031957:Domain of unknown function DUF4777 CG15579 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037350 CG2911 - http://flybase.org/reports/FBgn0037350 protein_coding_gene - - - CG2911 "IPR001623:DnaJ domain, IPR007872:Zinc finger, DPH-type, IPR018253:DnaJ domain, conserved site" CG2911 11-Aug-17 DroID_v2017_08 "Drer\dnaja3b, Drer\dnajc24, Drer\dnaja3a, Drer\dnajc16, Drer\dnajc16l" "Scer\JJJ3, Scer\JEM1, Scer\MDJ1" Cele\dnj-26 "Xtro\dnajc16, Xtro\dnajc24" "Mmus\Dnaja3, Mmus\Dnajc24, Mmus\Dnajc16" "Hsap\DNAJC24, Hsap\DNAJA3, Hsap\DNAJC16" viable FBgn0000553 e(dpy[v]) enhancer of dumpy-vortex http://flybase.org/reports/FBgn0000553 - gene - - - "vo-3, e(dpy[v]), e(dp[v])" - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0058198 CG40198 - http://flybase.org/reports/FBgn0058198 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE21703, CG40198" - CG40198 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086374 EP893 - http://flybase.org/reports/FBgn0086374 gene - - - EP893 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038356 CG12784 - http://flybase.org/reports/FBgn0038356 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12784 - CG12784 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003054 Pec Pupilla eccentrica http://flybase.org/reports/FBgn0003054 - gene - - - Pec - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive,eye color defective" "eye,heat sensitive,ocellus" FBgn0261002 Omar Omar http://flybase.org/reports/FBgn0261002 gene - - - "Omar, AGAR-82, AGAR-83" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0060947 l(3)S037906 lethal (3) S037906 http://flybase.org/reports/FBgn0060947 gene - - - "0379/06, l(3)S037906" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053757 CG33757 - http://flybase.org/reports/FBgn0053757 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33757 IPR010512:Protein of unknown function DUF1091 CG33757 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037142 CG14562 - http://flybase.org/reports/FBgn0037142 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available BLOC-2 complex ; GO:0031084 | inferred from sequence or structural similarity with HGNC:15597 "CG14562, anon-WO0140519.241, HPS3, NP_649372" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR029437:Hermansky-Pudlak syndrome 3 protein, N-terminal domain, IPR028167:Hermansky-Pudlak syndrome 3, central region" CG14562 11-Aug-17 DroID_v2017_08 Drer\hps3 - - Xtro\hps3 Mmus\Hps3 Hsap\HPS3 viable FBgn0001837 l(1)ts958 lethal (1) ts958 http://flybase.org/reports/FBgn0001837 - gene - - - l(1)ts958 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0029025 l(3)77ABg lethal (3) 77ABg http://flybase.org/reports/FBgn0029025 gene - - - l(3)77ABg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000747 fs(1)A330 female sterile (1) A330 http://flybase.org/reports/FBgn0000747 - gene - - - fs(1)A330 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,non-rescuable maternal effect,recessive,female sterile" embryo FBgn0031631 CG3225 - http://flybase.org/reports/FBgn0031631 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002464 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "cg3225, CG3225" "IPR001650:Helicase, C-terminal, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain" CG3225 11-Aug-17 DroID_v2017_08 "Drer\dhx8, Drer\dhx32b, Drer\dhx15, Drer\dhx32a, Drer\zgc:158828" "Scer\PRP43, Scer\PRP22, Scer\PRP16" "Cele\ddx-35, Cele\Y108F1.5" "Xtro\dhx38, Xtro\dhx15, Xtro\dhx16, Xtro\dhx8, Xtro\dhx35" "Mmus\Dhx15, Mmus\Dhx8, Mmus\Dhx16, Mmus\Dhx32, Mmus\Dqx1, Mmus\Dhx35" "Hsap\DHX35, Hsap\DQX1, Hsap\DHX32, Hsap\DHX15, Hsap\DHX16, Hsap\DHX38" "viable,visible" trichogen cell FBgn0033326 CG14743 - http://flybase.org/reports/FBgn0033326 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004837 CG14743 IPR004837:Sodium/calcium exchanger membrane region CG14743 11-Aug-17 DroID_v2017_08 Drer\slc8b1 "Scer\YDL206W, Scer\ECM27" "Cele\ncx-6, Cele\ncx-7, Cele\ncx-9, Cele\ncx-8, Cele\ncx-10" Xtro\slc8b1 Mmus\Slc8b1 Hsap\SLC8B1 viable FBgn0002899 mus301 mutagen-sensitive 301 http://flybase.org/reports/FBgn0002899 "FBgn0003481, FBgn0035843, FBgn0062073" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype regulation of translation ; GO:0006417 | traceable author statement polarity specification of dorsal/ventral axis ; GO:0009951 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with spn-A oogenesis ; GO:0048477 | traceable author statement RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 karyosome formation ; GO:0030717 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | traceable author statement female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype polarity specification of anterior/posterior axis ; GO:0009949 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from genetic interaction with fs(1)K10 - "spn-C, spnC, SpnC, mus(3)301, CG7972, cg7972, anon-WO0118547.354, mus301, Mus301" "IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7972 11-Aug-17 DroID_v2017_08 "Drer\polq, Drer\helq" Scer\SLH1 "Cele\helq-1, Cele\polq-1" "Xtro\polq, Xtro\helq" "Mmus\Helq, Mmus\Polq" "Hsap\HELQ, Hsap\POLQ, Hsap\DDX60" "chemical sensitive,recessive,viable,fertile,radiation sensitive" "chorion | maternal effect,karyosome,egg,maternal effect,oocyte nucleus,oocyte,egg chamber,dorsal appendage,synaptonemal complex,germline cyst,dorsal,nurse cell" FBgn0041585 olf186-F olf186-F http://flybase.org/reports/FBgn0041585 protein_coding_gene store-operated calcium channel activity ; GO:0015279 | inferred from direct assay store-operated calcium channel activity ; GO:0015279 | inferred from mutant phenotype positive regulation of calcium ion transport ; GO:0051928 | inferred from mutant phenotype store-operated calcium entry ; GO:0002115 | inferred from mutant phenotype positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001267146 integral component of plasma membrane ; GO:0005887 | non-traceable author statement "l(2)k11505, SPH206, CG11430, BcDNA:LD03241, olf186-F, dOrai, Orai, CRACM1, dorai, Olf186-F, dOrai1, orai, Orai1" IPR012446:Calcium release-activated calcium channel protein CG11430 11-Aug-17 DroID_v2017_08 "Drer\orai2, Drer\orai1a, Drer\orai1b" - Cele\orai-1 "Xtro\orai1, Xtro\orai2" "Mmus\Orai2, Mmus\Orai1, Mmus\Orai3" "Hsap\ORAI2, Hsap\ORAI3, Hsap\ORAI1" "lethal,recessive,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" dorsal medial muscle FBgn0259845 Su(Ste):CR42414 Su(Ste):CR42414 http://flybase.org/reports/FBgn0259845 non_protein_coding_gene - - - "Su(Ste):CR42414, RR41763, CR42414" - CR42414 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265484 BG02466 - http://flybase.org/reports/FBgn0265484 gene - - - BG02466 - - 11-Aug-17 DroID_v2017_08 - - - - - - "sleep defective,male limited" FBgn0065631 l(2)SH0782 lethal (2) SH0782 http://flybase.net/reports/FBgn0065631.html gene l(2)SH2 0782 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0015432 l(1)4ACa lethal (1) 4ACa http://flybase.org/reports/FBgn0015432 - gene - - - l(1)4ACa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004094 l(2)60Db lethal (2) 60Db http://flybase.org/reports/FBgn0004094 - gene - - - l(2)60Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0024205 ol3 oocyte localisation 3 http://flybase.org/reports/FBgn0024205 - gene - - - ol3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040143 l(1)G0487 lethal (1) G0487 http://flybase.org/reports/FBgn0040143 gene - - - l(1)G0487 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0014037 Su(Tpl) Su(Tpl) http://flybase.org/reports/FBgn0014037 "FBgn0016733, FBgn0025923, FBgn0028080, FBgn0028245, FBgn0028435, FBgn0036914, FBgn0052216, FBgn0052217" protein_coding_gene RNA polymerase binding ; GO:0070063 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7JRJ1 "snRNA transcription from RNA polymerase II promoter ; GO:0042795 | inferred from mutant phenotype regulation of DNA-templated transcription in response to stress ; GO:0043620 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay" transcription elongation factor complex ; GO:0008023 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay "l(3)76BDs, dELL, ELL, SR3-4A, SY3-1, SS3-4, Ell, l(3)S085401, 0854/01, l(3)S000606, CR32216, CG8037, CG32217, Su(Tpl), l (3)76BD, Su(Tpl)/, dell" "IPR010844:Occludin homology domain, IPR019464:RNA polymerase II elongation factor ELL, N-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR031176:ELL/occludin family" CG32217 11-Aug-17 DroID_v2017_08 "Drer\oclnb, Drer\LOC565819, Drer\ell, Drer\marveld2b, Drer\oclna, Drer\zgc:154006, Drer\si:ch73-61d6.3, Drer\si:dkey-208k22.6, Drer\ell2, Drer\marveld2a" - Cele\ell-1 "Xtro\ell, Xtro\ell2, Xtro\ell3, Xtro\ocel1, Xtro\marveld2" "Mmus\Ell2, Mmus\Marveld2, Mmus\Ell3, Mmus\Ocel1, Mmus\Ocln, Mmus\Ell" "Hsap\OCEL1, Hsap\ELL3, Hsap\OCLN, Hsap\ELL, Hsap\MARVELD2, Hsap\ELL2" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die" "eye,somatic clone,eye photoreceptor cell,pigment cell,embryonic metathoracic segment,embryonic mesothoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 4,embryonic abdominal segment 3,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic head,embryonic abdominal segment 8,macrochaeta,tormogen cell" DRSC26497 EK 0.013798626 1.044145927 1.038951321 1.654643023 -0.213354908 2.380758267 FBgn0033047 CG7882 - http://flybase.org/reports/FBgn0033047 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from electronic annotation with InterPro:IPR003663 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003663, InterPro:IPR005828" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 CG7882 "IPR003663:Sugar/inositol transporter, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG7882 11-Aug-17 DroID_v2017_08 "Drer\slc2a11l, Drer\slc2a3b, Drer\slc2a11a, Drer\slc2a15a, Drer\slc2a9l1, Drer\slc2a11b, Drer\slc2a15b, Drer\LOC100334818, Drer\slc2a2, Drer\slc2a3a, Drer\slc2a1a, Drer\LOC100331510, Drer\slc2a1b" "Scer\VPS73, Scer\HXT14, Scer\HXT7, Scer\YBR241C" "Cele\Y37A1A.3, Cele\K08H10.6, Cele\K09C4.1, Cele\F13B12.2, Cele\F11D5.7, Cele\K08F9.1, Cele\F53H8.3, Cele\slcf-2, Cele\C35A11.4, Cele\Y61A9LA.1, Cele\F11D5.5, Cele\F48E3.2, Cele\K09C4.4, Cele\C03B1.13, Cele\fgt-1, Cele\F14E5.1, Cele\Y39B6A.41, Cele\K09C4.5, Cele\Y39E4B.5, Cele\ZK829.9, Cele\R09B5.11" "Xtro\slc2a7, Xtro\slc2a9, Xtro\LOC100496725, Xtro\slc2a5, Xtro\slc2a2, Xtro\slc2a3, Xtro\slc2a11, Xtro\slc2a1" "Mmus\Slc2a5, Mmus\Slc2a2, Mmus\Slc2a7, Mmus\Slc2a4, Mmus\Slc2a3, Mmus\Slc2a9, Mmus\Slc2a1" "Hsap\SLC2A1, Hsap\SLC2A4, Hsap\SLC2A9, Hsap\SLC2A11, Hsap\SLC2A7, Hsap\MIF, Hsap\SLC2A14, Hsap\SLC2A3, Hsap\SLC2A2, Hsap\SLC2A5" "viable,fertile" FBgn0014297 l(3)64Bh lethal (3) 64Bh http://flybase.org/reports/FBgn0014297 - gene - - - l(3)64Bh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259319 C877 - http://flybase.org/reports/FBgn0259319 gene - - - C877 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0005383 Gtd Glucose tasting-defective http://flybase.org/reports/FBgn0005383 - gene - - - "GT-1, Gtd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,dominant,partially" FBgn0034270 PIG-A Phosphatidylinositol glycan anchor biosynthesis class A http://flybase.org/reports/FBgn0034270 protein_coding_gene phosphatidylinositol N-acetylglucosaminyltransferase activity ; GO:0017176 | inferred from biological aspect of ancestor with PANTHER:PTN000282535 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with HGNC:8957 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000282535 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from sequence or structural similarity with HGNC:8957 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506 | inferred from biological aspect of ancestor with PANTHER:PTN000282535 "Dm*AAF57802/5-442, CG6401, PIG-A" "IPR001296:Glycosyl transferase, family 1, IPR013234:PIGA, GPI anchor biosynthesis" CG6401 11-Aug-17 DroID_v2017_08 Drer\piga Scer\SPT14 Cele\piga-1 Xtro\piga Mmus\Piga Hsap\PIGA "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266066 CR44819 - http://flybase.org/reports/FBgn0266066 non_protein_coding_gene - - - CR44819 - CR44819 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005666 bt bent http://flybase.org/reports/FBgn0005666 "FBgn0000232, FBgn0004518, FBgn0004630, FBgn0005627, FBgn0039921, FBgn0052019" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271 actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 muscle alpha-actinin binding ; GO:0051371 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 structural constituent of muscle ; GO:0008307 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement structural molecule activity conferring elasticity ; GO:0097493 | inferred from biological aspect of ancestor with PANTHER:PTN001790569" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271 striated muscle contraction ; GO:0006941 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 protein phosphorylation ; GO:0006468 | non-traceable author statement muscle thin filament assembly ; GO:0071689 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern striated muscle myosin thick filament assembly ; GO:0071688 | inferred from biological aspect of ancestor with PANTHER:PTN001790569" Z disc ; GO:0030018 | inferred from direct assay muscle myosin complex ; GO:0005859 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 M band ; GO:0031430 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 I band ; GO:0031674 | inferred from direct assay sarcomere ; GO:0030017 | inferred from direct assay "bt, 39c-18, CG32019, CT8086, CT3598, CG1479, titin, l(4)PT-2, l(4)23, l(4)2, l(2)23, l(2)2, l(4)38, l(4)37, l(4)21, l(4)102CDa, Prj, CG10285, bent, Bt, projectin" "IPR000719:Protein kinase domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013783:Immunoglobulin-like fold, IPR017441:Protein kinase, ATP binding site, IPR013098:Immunoglobulin I-set" CG32019 11-Aug-17 DroID_v2017_08 "Drer\mylkb, Drer\egflam, Drer\vwa11, Drer\obsl1a, Drer\cd22, Drer\mybphb, Drer\mybpc1, Drer\zgc:171470, Drer\zmp:0000000971, Drer\myom1b, Drer\LOC100006752, Drer\vwa7, Drer\zgc:172106, Drer\LOC100333244, Drer\mybpc2b, Drer\vwa10.2, Drer\si:ch211-171h4.5, Drer\mylka, Drer\hmcn2, Drer\mybpc3, Drer\ttn.2, Drer\LOC100333105, Drer\si:ch211-1f22.3, Drer\ush2a, Drer\LOC100148735, Drer\ttnb, Drer\LOC101885775, Drer\mybpha, Drer\igfn1.4, Drer\sc:d0284, Drer\obsl1b, Drer\scospondin, Drer\obscnb, Drer\LOC100535144, Drer\si:ch211-286b5.9, Drer\mybpc2a, Drer\igfn1.2, Drer\zmp:0000001289, Drer\LOC101884775, Drer\si:ch73-380l3.2, Drer\spegb, Drer\vwa10.1" - "Cele\ttn-1, Cele\unc-22, Cele\let-805" "Xtro\hmcn2, Xtro\mylk, Xtro\egflam, Xtro\MGC89178" "Mmus\Ttn, Mmus\Mybphl, Mmus\Speg, Mmus\Ptk7, Mmus\Tnxb, Mmus\Myom2, Mmus\Mylk, Mmus\Mybpc2, Mmus\Hmcn2, Mmus\Hmcn1, Mmus\Mybph, Mmus\Obscn, Mmus\Ush2a, Mmus\Obsl1, Mmus\Egflam, Mmus\Myom1, Mmus\Vwa7, Mmus\Mybpc3, Mmus\Mybpc1" "Hsap\MYBPHL, Hsap\OBSCN, Hsap\TTN, Hsap\MYOM3, Hsap\TNC, Hsap\MYLK, Hsap\MYOM1, Hsap\VWA7, Hsap\SPEG, Hsap\MYBPC2, Hsap\IGFN1, Hsap\MYBPC1, Hsap\EGFLAM, Hsap\MYBPC3, Hsap\OBSL1, Hsap\USH2A, Hsap\MYOM2, Hsap\PTK7, Hsap\HMCN1, Hsap\IGSF22, Hsap\TNXB, Hsap\MYBPH" " larval stage , adult stage , pupal stage && adult stage " " larval muscle system

, adult muscle system

, synchronous muscle

, indirect flight muscle

" " adult stage , embryonic stage | late , larval stage--adult stage " " indirect flight muscle

, tubular muscle

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,dominant,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during pupal stage" "wing,leg,Z discMef2.PR" FBgn0041235 Gr59c Gustatory receptor 59c http://flybase.org/reports/FBgn0041235 protein_coding_gene bitter taste receptor activity ; GO:0033038 | inferred from mutant phenotype taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype taste receptor activity ; GO:0008527 | non-traceable author statement chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of bitter taste ; GO:0050913 | inferred from mutant phenotype sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr59D2, CG13543, 59D2, 59D.2, GR59D.2, CG30186, Gr59c, GR59c" IPR013604:7TM chemoreceptor CG30186 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - "neurophysiology defective,taste perception defective,partially lethal - majority die,some die during pupal stage" "I-type sensilla I8,I-type sensilla I9,I-type sensilla I10,S-type sensilla S5,S-type sensilla S6,I-type sensilla I5" FBgn0003223 rdt reduced thorax http://flybase.org/reports/FBgn0003223 - gene - - - rdt - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,poor,male sterile,visible" "wing,adult abdomen,adult head,adult thorax" FBgn0260960 Baldspot Baldspot http://flybase.org/reports/FBgn0260960 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with HGNC:15829 long-chain fatty acid biosynthetic process ; GO:0042759 | inferred from sequence or structural similarity with HGNC:15829 fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond spermatogenesis ; GO:0007283 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from sequence model mitochondrial outer membrane ; GO:0005741 | inferred from mutant phenotype "CG3971, blp, noa, l(3)neo22, l(3)02281, l(3)neo21, NEST:bs18g10, NEST:bs18f10, Baldspot, CG 3971, l(3)01895, l(3)04106, baldspot, Elovl6" "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG3971 11-Aug-17 DroID_v2017_08 "Drer\elovl6, Drer\elovl6l, Drer\zgc:92749" "Scer\ELO2, Scer\ELO3, Scer\ELO1" "Cele\elo-7, Cele\elo-4, Cele\elo-5, Cele\elo-6, Cele\elo-8, Cele\elo-1, Cele\elo-9, Cele\elo-2, Cele\elo-3" "Xtro\elovl3, Xtro\elovl6" "Mmus\Elovl6, Mmus\Elovl3" "Hsap\ELOVL3, Hsap\ELOVL6" FBgn0005279 M(2)p Minute (2) p http://flybase.org/reports/FBgn0005279 - gene - - - "M[[p]], M(2)p" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010531 Ccs Copper chaperone for superoxide dismutase http://flybase.org/reports/FBgn0010531 "FBgn0025541, FBgn0033487" protein_coding_gene superoxide dismutase copper chaperone activity ; GO:0016532 | inferred from direct assay copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 superoxide dismutase activity ; GO:0004784 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001424, InterPro:IPR018152 metal ion transport ; GO:0030001 | inferred from electronic annotation with InterPro:IPR006121 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from direct assay removal of superoxide radicals ; GO:0019430 | inferred from biological aspect of ancestor with PANTHER:PTN000000113" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000000114 cytoplasm ; GO:0005737 | inferred from direct assay peroxisome ; GO:0005777 | inferred from direct assay "CG17753, CCD, l(2)03221, anon-EST:Posey231, CCS, Ccs, DmCCS, CG-17753, dCCS" "IPR001424:Superoxide dismutase, copper/zinc binding domain, IPR018152:Superoxide dismutase, copper/zinc, binding site, IPR006121:Heavy metal-associated domain, HMA" CG17753 11-Aug-17 DroID_v2017_08 Drer\ccs "Scer\SOD1, Scer\CCS1" "Cele\sod-1, Cele\sod-5" Xtro\ccs Mmus\Ccs Hsap\CCS "short lived,chemical sensitive,recessive,lethal,viable" DRSC06692 I 1.684213878 0.155753272 0.605814959 0.187692758 -0.352762659 -0.213409319 FBgn0013461 fs(3)neo27 fs(3)neo27 http://flybase.org/reports/FBgn0013461 - gene - - - fs(3)neo27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal,maternal effect" FBgn0261808 cu curled http://flybase.org/reports/FBgn0261808 protein_coding_gene - locomotor rhythm ; GO:0045475 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from mutant phenotype nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay CCR4-NOT complex ; GO:0030014 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "no(cu), cu, CG4796, CG4782, CG31299, nocturnin, no, noc, noct" IPR005135:Endonuclease/exonuclease/phosphatase CG31299 11-Aug-17 DroID_v2017_08 "Drer\noctb, Drer\pde12, Drer\cnot6a, Drer\nocta, Drer\cnot6b, Drer\cnot6l" "Scer\NGL2, Scer\CCR4, Scer\NGL3, Scer\NGL1" Cele\pde-12 "Xtro\noct, Xtro\cnot6l" "Mmus\Lrrc27, Mmus\Noct, Mmus\Cnot6l, Mmus\Zfp503, Mmus\Cnot6, Mmus\Pde12, Mmus\Angel2" "Hsap\CNOT6, Hsap\PDE12, Hsap\ZNF503, Hsap\NOCT, Hsap\CNOT6L, Hsap\ANGEL2" FBgn0032938 CG8671 - http://flybase.org/reports/FBgn0032938 protein_coding_gene - dsRNA transport ; GO:0033227 | inferred from mutant phenotype - "anon-WO0118547.182, CG8671" IPR019448:EEIG1/EHBP1 N-terminal domain CG8671 11-Aug-17 DroID_v2017_08 "Drer\fam102ba, Drer\fam102aa, Drer\fam102bb, Drer\fam102ab" Scer\YBL086C Cele\sym-3 "Xtro\fam102b, Xtro\fam102a" "Mmus\Fam102b, Mmus\Fam102a" "Hsap\FAM102A, Hsap\FAM102B" FBgn0005046 E(var)43A Enhancer of variegation 43A http://flybase.org/reports/FBgn0005046 - gene - - - E(var)43A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024257 acd(2)5N29 auditory courtship defective 5N29 http://flybase.org/reports/FBgn0024257 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5N29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective" FBgn0053294 CR33294 - http://flybase.org/reports/FBgn0053294 pseudogene_attribute - - - "CG33294, CR33294, BP1027" - CR33294 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061082 l(3)S012613b lethal (3) S012613b http://flybase.org/reports/FBgn0061082 gene - - - "0126/13, l(3)S012613b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001098 Gdh Glutamate dehydrogenase http://flybase.org/reports/FBgn0001098 - protein_coding_gene glutamate dehydrogenase (NAD+) activity ; GO:0004352 | inferred from direct assay identical protein binding ; GO:0042802 | inferred from direct assay glutamate dehydrogenase [NAD(P)+] activity ; GO:0004353 | inferred from direct assay glutamate dehydrogenase [NAD(P)+] activity ; GO:0004353 | inferred from sequence or structural similarity with UniProt:P49448 inferred from sequence or structural similarity with UniProtKB:P00367 "cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR006095, InterPro:IPR006096, InterPro:IPR006097 NADH oxidation ; GO:0006116 | inferred from direct assay glutamate metabolic process ; GO:0006536 | inferred from direct assay glutamate catabolic process to 2-oxoglutarate ; GO:0019551 | inferred from sequence or structural similarity with UniProt:P49448 inferred from sequence or structural similarity with UniProtKB:P00367 sperm storage ; GO:0046693 | NOT traceable author statement" mitochondrion ; GO:0005739 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProt:P49448 inferred from sequence or structural similarity with UniProtKB:P00367 "Gdh, GDH, CG5320, gdh, GLUD, GLUD pre-mRNA, DHE3, GLU-D, Glud" "IPR006095:Glutamate/phenylalanine/leucine/valine dehydrogenase, IPR006096:Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal, IPR006097:Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain, IPR014362:Glutamate dehydrogenase, IPR016040:NAD(P)-binding domain, IPR033922:NAD(P) binding domain of glutamate dehydrogenase, IPR033524:Leu/Phe/Val dehydrogenases active site" CG5320 11-Aug-17 DroID_v2017_08 "Drer\glud1b, Drer\glud1a" "Scer\GDH1, Scer\GDH3" Cele\gdh-1 "Xtro\LOC100496343, Xtro\glud1" Mmus\Glud1 "Hsap\GLUD2, Hsap\GLUD1" "viable,fertile,electrophoretic variant" FBgn0026216 l(3)06948a lethal (3) 06948a http://flybase.org/reports/FBgn0026216 - gene - - - "l(3)06948, l(3)06948a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035112 CG13877 - http://flybase.org/reports/FBgn0035112 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13877 - CG13877 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031894 CG4496 - http://flybase.org/reports/FBgn0031894 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG4496 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4496 11-Aug-17 DroID_v2017_08 Drer\znf770 Scer\ZAP1 "Cele\Y37E11B.1, Cele\sdz-12, Cele\lst-5" Xtro\znf770 "Mmus\Zfp770, Mmus\Zfp655" "Hsap\ZNF770, Hsap\ZNF576, Hsap\ZNF655" viable FBgn0039829 CG15561 - http://flybase.org/reports/FBgn0039829 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467 - - CG15561 IPR000467:G-patch domain CG15561 11-Aug-17 DroID_v2017_08 "Drer\pinx1, Drer\gpatch4" "Scer\TMA23, Scer\PXR1" - "Xtro\pinx1, Xtro\gpatch4" "Mmus\Gpatch4, Mmus\Pinx1" "Hsap\PINX1, Hsap\GPATCH4" "viable,fertile" FBgn0032282 CG7299 - http://flybase.org/reports/FBgn0032282 protein_coding_gene - - - "CT22515, BcDNA:RE24635, CG7299" - CG7299 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary" FBgn0010830 l(3)04053 lethal (3) 04053 http://flybase.org/reports/FBgn0010830 "FBgn0011407, FBgn0037187" protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "l(3)j8B2, CG11238, l(3)04053" - CG11238 11-Aug-17 DroID_v2017_08 - - - Xtro\sdccag3 Mmus\Sdccag3 Hsap\SDCCAG3 "viable,fertile,lethal,recessive,partially lethal - majority die" FBgn0030981 CG14191 - http://flybase.org/reports/FBgn0030981 protein_coding_gene - - - "BcDNA:RE09269, CG14191" - CG14191 11-Aug-17 DroID_v2017_08 - - Cele\F16B4.5 - - Hsap\KRTAP5-5 "viable,visible" trichogen cell FBgn0266044 CR44809 - http://flybase.org/reports/FBgn0266044 non_protein_coding_gene - - - "CR44809, lincRNA.230" - CR44809 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263667 Lpt Lost PHDs of trr http://flybase.org/reports/FBgn0263667 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965 ligand-dependent nuclear receptor transcription coactivator activity ; GO:0030374 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model chromatin binding ; GO:0003682 | inferred from direct assay histone binding ; GO:0042393 | inferred from direct assay" "imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype inferred from genetic interaction with dpp positive regulation of histone H3-K9 trimethylation ; GO:1900114 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from genetic interaction with EcR inferred from genetic interaction with usp inferred from genetic interaction with trr histone H3-K4 methylation ; GO:0051568 | inferred from direct assay ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype" "ecdysone receptor holocomplex ; GO:0008230 | inferred from physical interaction with EcR, usp polytene chromosome ; GO:0005700 | inferred from direct assay nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay MLL3/4 complex ; GO:0044666 | inferred from direct assay" "CG5591, Cmi, Lpt, cg5591, cmi, LPT" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR001841:Zinc finger, RING-type, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR009071:High mobility group box domain" CG5591 11-Aug-17 DroID_v2017_08 "Drer\phf20l1, Drer\phf20b, Drer\ash1l, Drer\whsc1, Drer\nsd1b, Drer\kmt2d, Drer\kmt2e, Drer\kmt2cb, Drer\phf3, Drer\kmt2ca, Drer\setd1ba, Drer\whsc1l1" "Scer\SET2, Scer\CTI6, Scer\SET4, Scer\SET3, Scer\SET1, Scer\BYE1" "Cele\set-12, Cele\C16A11.4, Cele\set-16, Cele\set-26, Cele\met-1, Cele\lin-59, Cele\set-5, Cele\mes-4, Cele\set-9" "Xtro\kmt2c, Xtro\setd1b, Xtro\kmt2d" "Mmus\Whsc1, Mmus\Nsd1, Mmus\Phf3, Mmus\Setd2, Mmus\Ash1l, Mmus\Whsc1l1, Mmus\Spocd1, Mmus\Setd5, Mmus\Setd1a, Mmus\Kmt2d, Mmus\Phf20l1, Mmus\Kmt2e, Mmus\Setd1b, Mmus\Dido1, Mmus\Kmt2c" "Hsap\PHF20, Hsap\WHSC1, Hsap\KMT2D, Hsap\SETD1B, Hsap\KMT2E, Hsap\ASH1L, Hsap\SETD2, Hsap\SETD5, Hsap\KMT2C, Hsap\DIDO1, Hsap\PHF20L1, Hsap\SETD1A, Hsap\NSD1, Hsap\WHSC1L1" DRSC04515 EK 0.245977331 0.092606531 -2.608174849 1.215302843 -0.031328518 1.740426086 FBgn0011447 l(3)neo3 lethal (3) neo3 http://flybase.org/reports/FBgn0011447 - gene - - - l(3)neo3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043536 Obp57d Odorant-binding protein 57d http://flybase.org/reports/FBgn0043536 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 transport ; GO:0006810 | non-traceable author statement sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "Obp57e, 57d, OBP57d, Obp-g, anon-AE003791.1, CG30150, Obp57d, Dmel\Obp57d, DmelObp57d" IPR006170:Pheromone/general odorant binding protein CG30150 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004610 NaDh beta N-acetyl D-hexosaminidase http://flybase.org/reports/FBgn0004610 - gene beta-N-acetylhexosaminidase activity ; GO:0004563 | inferred from direct assay cuticle chitin catabolic process ; GO:0006036 | inferred from direct assay - NaDh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000554 ee extra eye http://flybase.org/reports/FBgn0000554 - gene molecular_function ; GO:0003674 | no biological data available eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ee - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive" "adult head,eye,ectopic,ocellus,antenna,rhabdomere" FBgn0020817 l(3)98Dm lethal (3) 98Dm http://flybase.org/reports/FBgn0020817 - gene - - - "M217, l(3)98Dm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266621 CR45128 - http://flybase.org/reports/FBgn0266621 non_protein_coding_gene - - - CR45128 - CR45128 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267237 CR45677 - http://flybase.org/reports/FBgn0267237 non_protein_coding_gene - - - CR45677 - CR45677 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002775 msl-3 male-specific lethal 3 http://flybase.org/reports/FBgn0002775 - protein_coding_gene mRNA binding ; GO:0003729 | traceable author statement RNA binding ; GO:0003723 | inferred from physical interaction with roX2 chromatin binding ; GO:0003682 | inferred from direct assay methylated histone binding ; GO:0035064 | inferred from direct assay dosage compensation by hyperactivation of X chromosome ; GO:0009047 | non-traceable author statement histone deacetylation ; GO:0016575 | inferred from biological aspect of ancestor with PANTHER:PTN000093964 dosage compensation by hyperactivation of X chromosome ; GO:0009047 | traceable author statement dosage compensation ; GO:0007549 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from biological aspect of ancestor with PANTHER:PTN000093963 histone H2A acetylation ; GO:0043968 | inferred from biological aspect of ancestor with PANTHER:PTN000093964 regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype dosage compensation ; GO:0007549 | traceable author statement histone H4 acetylation ; GO:0043967 | inferred from biological aspect of ancestor with PANTHER:PTN000093964 negative regulation of chromatin silencing ; GO:0031936 | inferred from mutant phenotype "X chromosome ; GO:0000805 | non-traceable author statement X chromosome ; GO:0000805 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | non-traceable author statement chromocenter ; GO:0010369 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | traceable author statement nuclear chromosome ; GO:0000228 | inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from biological aspect of ancestor with PANTHER:PTN000093964 MSL complex ; GO:0072487 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay" "MSL3, msl3, Msl3, msl, MSL-3, MSL, DmMsl-3, mls3, mle3, mle(3)132, CG8631, msl-3, Msl 1-3, MSL3_DROME" "IPR008676:MRG, IPR016197:Chromo domain-like, IPR026541:MRG domain" CG8631 11-Aug-17 DroID_v2017_08 "Drer\arid4a, Drer\morf4l1, Drer\arid4b" Scer\EAF3 - "Xtro\msl3, Xtro\msl3, Xtro\arid4b, Xtro\arid4a, Xtro\morf4l1" "Mmus\Morf4l1, Mmus\Msl3l2, Mmus\Msl3, Mmus\Arid4a, Mmus\Arid4b, Mmus\Morf4l2" "Hsap\MORF4L1, Hsap\ARID4B, Hsap\ARID4A, Hsap\MSL3, Hsap\MORF4L2" " larval stage | female , larval stage | male " "developmental rate defective,male sterile,wild-type,lethal,male,recessive,lethal - all die before end of larval stage,some die during larval stage,non-suppressor of variegation,dominant,suppressor of variegation,visible,male limited,somatic clone,viable" "wing,eye,male limited,somatic clone" FBgn0265767 zyd zydeco http://flybase.org/reports/FBgn0265767 protein_coding_gene "calcium, potassium:sodium antiporter activity ; GO:0008273 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 sodium ion binding ; GO:0031402 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 potassium ion binding ; GO:0030955 | inferred from biological aspect of ancestor with PANTHER:PTN000090975" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 cellular calcium ion homeostasis ; GO:0006874 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 "CG2893, zyd, zydeco, CG40147, CK02262, BEST:CK02262" "IPR004481:Sodium/potassium/calcium exchanger, IPR004837:Sodium/calcium exchanger membrane region" CG2893 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-335m24.5, Drer\slc24a4b, Drer\slc24a3, Drer\slc24a1, Drer\slc24a2, Drer\slc24a4a, Drer\slc24a5" "Scer\ECM27, Scer\YDL206W" "Cele\ncx-8, Cele\ncx-9, Cele\ncx-7, Cele\ncx-5, Cele\ncx-4, Cele\ncx-6" "Xtro\slc24a2, Xtro\slc24a5, Xtro\slc24a3, Xtro\slc24a4" "Mmus\Slc24a4, Mmus\Slc24a1, Mmus\Slc24a5, Mmus\Slc24a3, Mmus\Slc8b1, Mmus\Slc24a2" "Hsap\SLC24A4, Hsap\SLC24A2, Hsap\SLC24A5, Hsap\SLC8B1, Hsap\SLC24A3, Hsap\SLC24A1" "bang sensitive,viable,behavior defective,recessive,heat sensitive,neurophysiology defective,partially lethal - majority die" FBgn0029813 CG15766 - http://flybase.org/reports/FBgn0029813 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 CG15766 "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG15766 11-Aug-17 DroID_v2017_08 - - "Cele\R05H10.1, Cele\W02D7.4, Cele\anat-1, Cele\T10B5.4, Cele\M7.12, Cele\R05H10.7, Cele\W02D7.5, Cele\M7.8" - - - "viable,fertile" FBgn0265669 CG44476 - http://flybase.org/reports/FBgn0265669 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lincRNA.179, CG44476" - CG44476 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065651 l(2)SH0733 lethal (2) SH0733 http://flybase.org/reports/FBgn0065651 gene - - - "l(2)SH0733, l(2)SH2 0733" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259823 CG42404 - http://flybase.org/reports/FBgn0259823 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42404, CG34128, CG31154, BcDNA:SD12744, CG4285, lincRNA.S6902" IPR001007:VWFC domain CG42404 11-Aug-17 DroID_v2017_08 Drer\dgcr2 - - - Mmus\Dgcr2 Hsap\DGCR2 FBgn0061159 l(1)7Fh lethal (1) 7Fh http://flybase.org/reports/FBgn0061159 gene - - - l(1)7Fh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "melanotic mass,melanotic mass & salivary gland,melanotic mass & tracheal system" FBgn0033569 CG12942 - http://flybase.org/reports/FBgn0033569 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG12942 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG12942 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-33c14.6, Drer\zbtb41, Drer\si:dkey-14k9.3, Drer\atmin" Scer\CRZ1 "Cele\ZK686.5, Cele\eor-1, Cele\row-1, Cele\Y55F3AM.14, Cele\Y111B2A.10" "Xtro\zbtb41, Xtro\atmin" "Mmus\Atmin, Mmus\Zbtb41" "Hsap\ZBTB41, Hsap\ZNF124" viable FBgn0011870 tRNA:Gly-GCC-1-11 transfer RNA:Glycine-GCC 1-11 http://flybase.org/reports/FBgn0011870 "FBgn0003782, FBgn0050138, FBgn0060215" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "AE002787.trna59-GlyGCC, tRNA:G:GCC:AE002787-d, CR30138, tRNA:gly3:56EFb, tRNA[Gly-GCC], chr2R.trna43-GlyGCC, tRNA-Gly-GCC-1-11, tRNA:Gly-GCC-1-11, tRNA:G3:56EFb, GGC" - CR30138 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040901 CG13757 - http://flybase.org/reports/FBgn0040901 protein_coding_gene - - - CG13757 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001710 l(1)ESHS31 lethal (1) ESHS31 http://flybase.org/reports/FBgn0001710 - gene - - - l(1)ESHS31 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027512 CG10254 - http://flybase.org/reports/FBgn0027512 - protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:29554 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 protein monoubiquitination ; GO:0006513 | inferred from sequence or structural similarity with HGNC:29554 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:29554 "BcDNA:LD22087, CG10254" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG10254 11-Aug-17 DroID_v2017_08 Drer\LOC100331775 - Cele\ubc-17 - "Mmus\Ube2o, Mmus\Ube2z" "Hsap\UBE2O, Hsap\UBE2Z" viable FBgn0016974 swaPsi swallow pseudogene http://flybase.org/reports/FBgn0016974 FBgn0052747 pseudogene_attribute - - - "CG3429, CR32747, swaPsi" - CR32747 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032119 CG3769 - http://flybase.org/reports/FBgn0032119 protein_coding_gene dynein heavy chain binding ; GO:0045504 | inferred from biological aspect of ancestor with PANTHER:PTN000326085 dynein heavy chain binding ; GO:0045504 | inferred from sequence or structural similarity with UniProtKB:Q6AY43 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000326085 axoneme ; GO:0005930 | inferred from sequence or structural similarity with UniProtKB:Q8K0T2 axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000326085 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN000326085 CG3769 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022780:Dynein family light intermediate chain" CG3769 11-Aug-17 DroID_v2017_08 Drer\dync2li1 - Cele\xbx-1 "Xtro\dync2li1, Xtro\LOC100498570" Mmus\Dync2li1 Hsap\DYNC2LI1 viable FBgn0016881 l(2)39DEf lethal (2) 39DEf http://flybase.org/reports/FBgn0016881 - gene - - - "I4, l(2)39DEf" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024357 ES3-1 Enhancer of GMR-sina 3-1 http://flybase.org/reports/FBgn0024357 - gene - - - ES3-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082935 snoRNA:Me28S-G1083a snoRNA:Me28S-G1083a http://flybase.org/reports/FBgn0082935 snoRNA_gene rRNA 2'-O-ribose methylation guide activity ; GO:0030562 | inferred from sequence model rRNA 2'-O-methylation ; GO:0000451 | inferred from sequence model nucleolus ; GO:0005730 | inferred from direct assay "snoRNA:Me28S-G1083a, Me28S-Gm1083a, Me28S-G1083a(DmSnR60), CR34562, DmSnR60, DmSnR60a" - CR34562 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050458 CG30458 - http://flybase.org/reports/FBgn0050458 protein_coding_gene - - - "CG17288, CG30458" IPR004011:GYR motif CG30458 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265421 CR44333 - http://flybase.org/reports/FBgn0265421 non_protein_coding_gene - - - CR44333 - CR44333 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035168 cep290 cep290 http://flybase.org/reports/FBgn0035168 protein_coding_gene - non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype ciliary transition zone assembly ; GO:1905349 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from mutant phenotype ciliary transition zone ; GO:0035869 | inferred from direct assay "CG13889, Q9W0M1_DROME, cep290, Cep290" - CG13889 11-Aug-17 DroID_v2017_08 "Drer\cep290, Drer\cep120" - - - "Mmus\Cep290, Mmus\Cep120" "Hsap\CEP120, Hsap\CEP290" "viable,smell perception defective,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0031000 Muc18B Mucin 18B http://flybase.org/reports/FBgn0031000 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "Muc18B, CG7876" IPR002557:Chitin binding domain CG7876 11-Aug-17 DroID_v2017_08 Drer\podxl - Cele\F33E2.6 - "Mmus\2300002M23Rik, Mmus\Hhipl2" "Hsap\C6orf15, Hsap\HHIPL2" FBgn0082635 S(CycE[JP])2.10 S(CycE[JP])2.10 http://flybase.org/reports/FBgn0082635 gene - - - S(CycE[JP])2.10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0046843 ird25 immune response deficient 25 http://flybase.org/reports/FBgn0046843 gene molecular_function ; GO:0003674 | no biological data available humoral immune response ; GO:0006959 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ird25 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,immune response defective" FBgn0259273 EP-471 - http://flybase.org/reports/FBgn0259273 gene - - - EP-471 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta,ectopic" FBgn0259283 C544 - http://flybase.org/reports/FBgn0259283 gene - - - C544 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0266068 CR44821 - http://flybase.org/reports/FBgn0266068 non_protein_coding_gene - - - CR44821 - CR44821 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037105 S1P S1P http://flybase.org/reports/FBgn0037105 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR000209 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000209 sterol regulatory element binding protein cleavage ; GO:0035103 | non-traceable author statement - "dS1P, CG7169, S1P, SKI-1/S1P" "IPR000209:Peptidase S8/S53 domain, IPR015500:Peptidase S8, subtilisin-related, IPR029062:Class I glutamine amidotransferase-like, IPR034185:Site-1 peptidase catalytic domain, IPR022398:Peptidase S8, subtilisin, His-active site, IPR023828:Peptidase S8, subtilisin, Ser-active site" CG7169 11-Aug-17 DroID_v2017_08 "Drer\pcsk9, Drer\mbtps1" "Scer\RRT12, Scer\YSP3, Scer\PRB1" Cele\tpp-2 Xtro\mbtps1 "Mmus\Pcsk9, Mmus\Mbtps1" Hsap\MBTPS1 viable FBgn0061067 l(3)S020004b lethal (3) S020004b http://flybase.org/reports/FBgn0061067 gene - - - "0200/04, l(3)S020004b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0036834 CG6836 - http://flybase.org/reports/FBgn0036834 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 transporter activity ; GO:0005215 | inferred from sequence or structural similarity with UniProtKB:Q8R000 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:Q8R000 transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q8R000 CG6836 IPR005178:Organic solute transporter subunit alpha/Transmembrane protein 184 CG6836 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-16n15.6, Drer\slc51a, Drer\tmem184bb, Drer\tmem184a, Drer\tmem184c, Drer\tmem184ba, Drer\si:dkey-217f16.5" Scer\YKR051W "Cele\osta-2, Cele\osta-1, Cele\osta-3, Cele\F40E10.6" "Xtro\slc51a, Xtro\tmem184a, Xtro\slc51a, Xtro\tmem184b, Xtro\tmem184c" "Mmus\Tmem184b, Mmus\Tmem184c, Mmus\Slc51a, Mmus\Tmem184a" "Hsap\SLC51A, Hsap\TMEM184C, Hsap\TMEM184B, Hsap\TMEM184A" viable FBgn0051588 tRNA:Phe-GAA-1-6 transfer RNA:Phenylalanine-GAA 1-6 http://flybase.org/reports/FBgn0051588 tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "AE002708.trna5-PheGAA, tRNA:F:GAA:AE002708-a, CR31588, chr3R.trna11-PheGAA, tRNA-Phe-GAA-1-6, tRNA:Phe-GAA-1-6, tRNA:CR31588, UUC" - CR31588 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069099 mus326 mutagen-sensitive 326 http://flybase.org/reports/FBgn0069099 gene - - - mus326 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0028616 l(2)W1 lethal (2) W1 http://flybase.org/reports/FBgn0028616 gene - - - "l(2R)W1, l(2)W1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267473 CR45823 - http://flybase.org/reports/FBgn0267473 non_protein_coding_gene - - - CR45823 - CR45823 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267777 CR46108 - http://flybase.org/reports/FBgn0267777 non_protein_coding_gene - - - CR46108 - CR46108 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033984 Lap1 Lap1 http://flybase.org/reports/FBgn0033984 protein_coding_gene - signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN002351852 maintenance of epithelial cell apical/basal polarity ; GO:0045199 | inferred from biological aspect of ancestor with PANTHER:PTN002352077 protein transport ; GO:0015031 | inferred from sequence or structural similarity with UniProtKB:O61967 establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement establishment or maintenance of cell polarity ; GO:0007163 | inferred from sequence or structural similarity with UniProtKB:O61967 adherens junction ; GO:0005912 | inferred from sequence or structural similarity with UniProtKB:O61967 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN002352077 basolateral plasma membrane ; GO:0016323 | inferred from biological aspect of ancestor with PANTHER:PTN002352077 "dLAP1, dlap1, CT28815, CG10255, Lap1" "IPR001478:PDZ domain, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG10255 11-Aug-17 DroID_v2017_08 "Drer\erbb2ip, Drer\lrrc7, Drer\lrrc1" - Cele\let-413 "Xtro\erbb2ip, Xtro\lrrc7, Xtro\lrrc1" "Mmus\Lrrd1, Mmus\Scrib, Mmus\Lrrc7, Mmus\Erbin, Mmus\Lrch4, Mmus\Lrrc1" "Hsap\LRRD1, Hsap\LRRC7, Hsap\LRCH4, Hsap\ERBIN, Hsap\SCRIB, Hsap\LRRC1" viable FBgn0267624 CR45962 - http://flybase.org/reports/FBgn0267624 non_protein_coding_gene - - - CR45962 - CR45962 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065331 l(2)SH1882 lethal (2) SH1882 http://flybase.org/reports/FBgn0065331 gene - - - "l(2)SH1882, l(2)SH2 1882" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020930 Dgkepsilon Diacyl glycerol kinase epsilon http://flybase.org/reports/FBgn0020930 - protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 diacylglycerol kinase activity ; GO:0004143 | inferred from direct assay diacylglycerol kinase activity ; GO:0004143 | non-traceable author statement protein kinase C-activating G-protein coupled receptor signaling pathway ; GO:0007205 | inferred from electronic annotation with InterPro:IPR000756 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 phosphorylation ; GO:0016310 | inferred from direct assay phosphorylation ; GO:0016310 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CG8657, DGKepsilon, DGKe, Dgkepsilon, dgkepsilon" "IPR000756:Diacylglycerol kinase, accessory domain, IPR001206:Diacylglycerol kinase, catalytic domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG8657 11-Aug-17 DroID_v2017_08 "Drer\dgkb, Drer\dgke, Drer\LOC567728, Drer\dgkaa" - Cele\dgk-2 "Xtro\dgka, Xtro\dgkq, Xtro\dgke, Xtro\dgkb" "Mmus\Dgka, Mmus\Dgke, Mmus\Dgkb, Mmus\Dgkg, Mmus\Dgkq" "Hsap\DGKA, Hsap\DGKQ, Hsap\DGKG, Hsap\DGKB, Hsap\DGKE" "viable,fertile,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0085792 CR41509 - http://flybase.org/reports/FBgn0085792 pseudogene_attribute - - - CR41509 - CR41509 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011958 tRNA:Arg-ACG-1-1 transfer RNA:Arginine-ACG 1-1 http://flybase.org/reports/FBgn0011958 "FBgn0003757, FBgn0011947, FBgn0050304, FBgn0060091" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "CR30304, 35DArg, tRNA[arg], tRNA[Arg][[2]], AE002769.trna10-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002769-b, tRNA:arg2:42Ad, tRNA[Arg], chr2R.trna1-ArgACG, tRNA-Arg-ACG-1-1, tRNA:Arg-ACG-1-1, tRNA:R2:42Ad, CGU" - CR30304 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262097 CR42850 - http://flybase.org/reports/FBgn0262097 non_protein_coding_gene - - - "CG42850, CR42850" - CR42850 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259832 CG34229 - http://flybase.org/reports/FBgn0259832 protein_coding_gene - - - "CG34229, CG13191, Sdh6" "IPR008011:Complex 1 LYR protein, IPR026868:LYR motif-containing protein 2" CG34229 11-Aug-17 DroID_v2017_08 Drer\lyrm2 - - Xtro\lyrm2 Mmus\Lyrm2 Hsap\LYRM2 FBgn0262291 mir-956 mir-956 stem loop http://flybase.org/reports/FBgn0262291 miRNA_gene - - - "dme-mir-956, mir-956, miR-956, CR42998, dme-miR-956, dme-miR-956-5p" - CR42998 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025455 CycT Cyclin T http://flybase.org/reports/FBgn0025455 FBgn0023101 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR015430 cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from sequence or structural similarity with CycC inferred from sequence or structural similarity with CycH RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | traceable author statement cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 "actin filament organization ; GO:0007015 | inferred from mutant phenotype positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 ventral cord development ; GO:0007419 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of phosphorylation of RNA polymerase II C-terminal domain ; GO:1901409 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from direct assay" cyclin/CDK positive transcription elongation factor complex ; GO:0008024 | traceable author statement polytene chromosome puff ; GO:0005703 | inferred from direct assay cyclin/CDK positive transcription elongation factor complex ; GO:0008024 | inferred from physical interaction with Cdk9 polytene chromosome ; GO:0005700 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from direct assay ELL-EAF complex ; GO:0032783 | inferred from physical interaction with Su(Tpl) nucleus ; GO:0005634 | inferred from direct assay "P-TEFb, dT, p124, Dmcyclin T, anon-74EFc, CG6292, CycT, ORE-14" "IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like, IPR015430:Cyclin T" CG6292 11-Aug-17 DroID_v2017_08 "Drer\ccnt2a, Drer\fam58a, Drer\ccnk, Drer\ccnt2b, Drer\ccnt1" "Scer\BUR2, Scer\CTK2, Scer\SSN8" "Cele\cit-1.2, Cele\cit-1.1" "Xtro\ccnt1, Xtro\ccnk, Xtro\ccnt2, Xtro\fam58a" "Mmus\Fam58b, Mmus\Ccnt1, Mmus\Ccnk, Mmus\Ccnt2" "Hsap\CCNT2, Hsap\CCNK, Hsap\CCNT1, Hsap\FAM58A" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC23304 IEK 0.026374515 4.105745829 1.594790678 -3.290926669 2.870076554 4.172031086 FBgn0053988 Mid1 Mid1 http://flybase.org/reports/FBgn0053988 protein_coding_gene "stretch-activated, cation-selective, calcium channel activity ; GO:0015275 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001813413" locomotor rhythm ; GO:0045475 | inferred from mutant phenotype calcium ion import across plasma membrane ; GO:0098703 | inferred from biological aspect of ancestor with PANTHER:PTN001813413 social behavior ; GO:0035176 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001813413 "CG18510, CG13596, CG13595, cg13596, CG33988, Mid1, Nlf-1" IPR020067:Frizzled domain CG33988 11-Aug-17 DroID_v2017_08 "Drer\fam155b, Drer\LOC101886421" Scer\MID1 - - "Mmus\Tmem28, Mmus\Fam155a" "Hsap\FAM155B, Hsap\FAM155A" "locomotor rhythm defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "chaeta,supernumerary" DRSC04231 K -0.747885446 0.148291502 -0.347758993 0.29937545 -1.509966451 -0.782567918 FBgn0084065 2.2.2 2.2.2 http://flybase.org/reports/FBgn0084065 gene - - - 2.2.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0013739 usdy unsteady http://flybase.org/reports/FBgn0013739 - gene molecular_function ; GO:0003674 | no biological data available grooming behavior ; GO:0007625 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available usdy - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive" FBgn0024927 Su(var)2-b801 Su(var)2-b801 http://flybase.org/reports/FBgn0024927 - gene - - - "Su-var(2)b801, Su(var)2-b801" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063383 snoRNA:U29:54Ec snoRNA:U29:54Ec http://flybase.org/reports/FBgn0063383 snoRNA_gene - - - "U29snoRNA, CR32894, snoRNA:U29:54Ec, chr2R:13215315..13215434" - CR32894 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051225 Ir94f Ionotropic receptor 94f http://flybase.org/reports/FBgn0051225 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir94f, IR94f, CG31225, DmelIR94f" - CG31225 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060487 l(3)S110408 lethal (3) S110408 http://flybase.org/reports/FBgn0060487 gene - - - "1104/08, l(3)S110408" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014118 anon-96Fc anon-96Fc http://flybase.org/reports/FBgn0014118 - gene - - - anon-96Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , larval stage " " adult head

, eye-antennal disc

" FBgn0260007 CG42493 - http://flybase.org/reports/FBgn0260007 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42493 - CG42493 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053399 5SrRNA:CR33399 5SrRNA:CR33399 http://flybase.org/reports/FBgn0053399 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33399, 5SrRNA:CR33399" - CR33399 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262428 mir-87 mir-87 stem loop http://flybase.org/reports/FBgn0262428 miRNA_gene - - - "miR-87, mir-87, MIR-87, CR42983, CR32981" - CR42983 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , prepupal stage--adult stage , larval stage | first instar , larval stage | second instar " "viable,visible" wing FBgn0010371 meso60A mesoderm specific 60A http://flybase.org/reports/FBgn0010371 - gene - - - meso60A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016808 l(1)L1 lethal (1) L1 http://flybase.org/reports/FBgn0016808 - gene - - - "l(1)L1, L1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003451 snl sonless http://flybase.org/reports/FBgn0003451 - gene - - - snl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male,maternal effect,recessive,partially lethal - majority die" FBgn0019735 l(1)9e3-21 lethal (1) 9e3-21 http://flybase.org/reports/FBgn0019735 - gene - - - l(1)9e3-21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266154 CR44860 - http://flybase.org/reports/FBgn0266154 non_protein_coding_gene - - - CR44860 - CR44860 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030880 CG6788 - http://flybase.org/reports/FBgn0030880 protein_coding_gene - - - "CG6788, AAF48780, FBpp0074269" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR020837:Fibrinogen, conserved site, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG6788 11-Aug-17 DroID_v2017_08 "Drer\LOC100334800, Drer\angpt1, Drer\tnr, Drer\si:dkeyp-51b7.3, Drer\mfap4, Drer\si:ch211-157b11.8, Drer\LOC555374, Drer\fgl1, Drer\angptl6, Drer\si:ch211-203k16.3, Drer\angptl7, Drer\tnc, Drer\si:zfos-2330d3.6, Drer\angptl4, Drer\angpt2a, Drer\si:zfos-2330d3.1, Drer\si:zfos-2330d3.8, Drer\fndc7a, Drer\fgl2a, Drer\tnxba, Drer\si:ch211-287a12.9, Drer\angpt4, Drer\fgb, Drer\wu:fj11g02, Drer\LOC100007488, Drer\si:ch1073-110a20.2, Drer\fgg, Drer\zgc:194887, Drer\si:zfos-2330d3.3, Drer\si:ch1073-110a20.1, Drer\fibcd1, Drer\angptl2b, Drer\angptl5, Drer\angptl2a, Drer\zmp:0000000846, Drer\zgc:173915, Drer\fgl2b, Drer\zgc:171687, Drer\fga, Drer\angptl3, Drer\angpt2b, Drer\tnw, Drer\angptl1a, Drer\si:ch1073-110a20.3" Scer\SMC1 "Cele\Y69H2.10, Cele\ensh-1, Cele\T15B7.1, Cele\Y69H2.3, Cele\eea-1, Cele\Y26D4A.12, Cele\C08G9.2, Cele\W05B2.2, Cele\Y43C5A.2, Cele\ZC504.1, Cele\K10D3.4" "Xtro\fcn1, Xtro\fcn3, Xtro\tnn, Xtro\LOC100491105, Xtro\angpt1, Xtro\LOC100488177, Xtro\LOC100497330, Xtro\tnr, Xtro\fga, Xtro\tnc, Xtro\mfap4, Xtro\fibcd1, Xtro\angptl4, Xtro\angptl2, Xtro\fgl2, Xtro\fcn2, Xtro\fgg, Xtro\angptl5, Xtro\fgl1, Xtro\angpt4, Xtro\tnxb, Xtro\angptl3, Xtro\fgb" "Mmus\Tnn, Mmus\Angpt2, Mmus\Fcnb, Mmus\Fibcd1, Mmus\Angptl4, Mmus\Fcna, Mmus\Angpt1, Mmus\Angpt4, Mmus\Mfap4, Mmus\Fgb, Mmus\Angptl2, Mmus\Tnc, Mmus\Angptl7, Mmus\Tnxb, Mmus\Fndc7, Mmus\Fgl2, Mmus\Fga, Mmus\Fgg, Mmus\Angptl1, Mmus\Angptl6, Mmus\Fgl1, Mmus\Tnr, Mmus\Angptl3" "Hsap\FGG, Hsap\FGL1, Hsap\ANGPTL4, Hsap\ANGPTL3, Hsap\ANGPT1, Hsap\FGL2, Hsap\TNC, Hsap\ANGPTL1, Hsap\TNN, Hsap\ANGPT2, Hsap\ANGPTL5, Hsap\ANGPTL2, Hsap\ANGPT4, Hsap\FCN1, Hsap\FCN2, Hsap\ANGPTL6, Hsap\ANGPTL7, Hsap\TNXB, Hsap\FIBCD1, Hsap\FGA, Hsap\FNDC7, Hsap\MFAP4, Hsap\FGB, Hsap\FCN3, Hsap\TNR" viable FBgn0000431 den denervated http://flybase.org/reports/FBgn0000431 - gene - - - den - - 11-Aug-17 DroID_v2017_08 - - - - - - nervous system FBgn0261615 CG42704 - http://flybase.org/reports/FBgn0261615 protein_coding_gene - - - CG42704 - CG42704 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024646 l(2)k09810 lethal (2) k09810 http://flybase.org/reports/FBgn0024646 - gene - - - l(2)k09810 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065944 l(2)SH0108 lethal (2) SH0108 http://flybase.net/reports/FBgn0065944.html gene l(2)SH2 0108 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0029815 CG11462 - http://flybase.org/reports/FBgn0029815 protein_coding_gene - - - "BcDNA:GH09844, CG11462" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC25663 K -1.617307862 -0.236999708 FBgn0024790 Doc\RTase Doc element RTase http://flybase.org/reports/FBgn0024790 - transposable_element_gene - - - "ORF2, Doc\RTase, RT" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038740 CG4562 - http://flybase.org/reports/FBgn0038740 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "Dme_CG4562, CT14766, CG4562" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG4562 11-Aug-17 DroID_v2017_08 "Drer\abcc13, Drer\abcc2, Drer\abcc12, Drer\abcc8, Drer\abcc3, Drer\abcc4, Drer\abcc1, Drer\LOC100329706, Drer\abcc6a, Drer\abcc6b.2, Drer\abcc10, Drer\abcc9, Drer\cftr, Drer\abcc5" "Scer\STE6, Scer\NFT1, Scer\BPT1, Scer\YCF1, Scer\YBT1, Scer\YOR1, Scer\YKR104W, Scer\VMR1" "Cele\mrp-4, Cele\mrp-3, Cele\mrp-5, Cele\mrp-7, Cele\mrp-1, Cele\mrp-6, Cele\mrp-2, Cele\mrp-8" "Xtro\abcc4, Xtro\cftr, Xtro\abcc6, Xtro\abcc1, Xtro\abcc10, Xtro\abcc3" "Mmus\Abcc8, Mmus\Abcc5, Mmus\Abcc12, Mmus\Abcc3, Mmus\Abcc9, Mmus\Abcc6, Mmus\Abcc2, Mmus\Cftr, Mmus\Abcc10, Mmus\Abcc1, Mmus\Abcc4" "Hsap\ABCC12, Hsap\ABCC3, Hsap\ABCC1, Hsap\ABCC6, Hsap\ABCC8, Hsap\ABCC5, Hsap\ABCC11, Hsap\ABCC4, Hsap\CFTR, Hsap\ABCC2, Hsap\ABCC10, Hsap\ABCC9" viable FBgn0051219 CG31219 - http://flybase.org/reports/FBgn0051219 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG16731, CG31219" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG31219 11-Aug-17 DroID_v2017_08 - - "Cele\try-8, Cele\try-3, Cele\F25E5.3, Cele\F25E5.7, Cele\F25E5.4, Cele\try-1, Cele\T21E12.3, Cele\svh-1" - - - viable FBgn0016726 RpL29 Ribosomal protein L29 http://flybase.org/reports/FBgn0016726 "FBgn0025285, FBgn0025305, FBgn0061374" protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR002673 structural constituent of ribosome ; GO:0003735 | traceable author statement chromatin binding ; GO:0003682 | inferred from genetic interaction with His1 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002673 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR002673 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG10071, anon-EST:Posey204, DL43, anon-EST:Posey73, RpL43, BcDNA:RH58777, RpL29, L29" IPR002673:Ribosomal protein L29e CG10071 11-Aug-17 DroID_v2017_08 Drer\rpl29 Scer\RPL29 Cele\rpl-29 Xtro\rpl29 Mmus\Rpl29 Hsap\RPL29 FBgn0044490 DTD46.8 DTD46.8 http://flybase.org/reports/FBgn0044490 gene - - - DTD46.8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034486 CG13869 - http://flybase.org/reports/FBgn0034486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13869 IPR006631:Protein of unknown function DM4/12 CG13869 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283678 Osi21 Osiris 21 http://flybase.org/reports/FBgn0283678 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "die4, Osi21, CG14925, diehard4" IPR012464:Protein of unknown function DUF1676 CG14925 11-Aug-17 DroID_v2017_08 - - - - - - "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0000661 fl(1)302 female lethal 302 http://flybase.org/reports/FBgn0000661 - gene - - - fl(1)302 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female,viable,male" FBgn0264872 CR44063 - http://flybase.org/reports/FBgn0264872 non_protein_coding_gene - - - CR44063 - CR44063 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034013 unc-5 unc-5 http://flybase.org/reports/FBgn0034013 protein_coding_gene netrin receptor activity involved in chemorepulsion ; GO:0005043 | inferred from sequence or structural similarity signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000488 salivary gland boundary specification ; GO:0007432 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with NetB glial cell migration ; GO:0008347 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with NetA inferred from genetic interaction with NetB - "Unc-5, Unc5d, CG8166, UNC5, Unc5, UNC5D, CT20824, AAF7419, Dunc5, CG8168, unc-5, unc5, UNC-5, dUnc5" "IPR000488:Death domain, IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR000906:ZU5 domain, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR011029:Death-like domain, IPR013783:Immunoglobulin-like fold, IPR033772:UPA domain, IPR013098:Immunoglobulin I-set, IPR003599:Immunoglobulin subtype" CG8166 11-Aug-17 DroID_v2017_08 "Drer\unc5c, Drer\unc5b, Drer\si:ch73-72b7.1, Drer\unc5db, Drer\unc5da, Drer\unc5a" - Cele\unc-5 "Xtro\unc5d, Xtro\unc5c, Xtro\unc5b" "Mmus\Unc5a, Mmus\Unc5c, Mmus\Unc5d, Mmus\Unc5cl, Mmus\Unc5b" "Hsap\UNC5CL, Hsap\UNC5B, Hsap\UNC5A, Hsap\UNC5D, Hsap\UNC5C" "neuroanatomy defective,locomotor rhythm defective,lethal,viable" "intersegmental nerve,anterior commissure,posterior commissure,ventral nerve cord,embryonic/larval neuron,interface glial cell | embryonic stage,abdominal segmental nerve,presumptive embryonic salivary gland,serotonin neuron & ventral nerve cordeg-Mz360,cell body & serotonin neuroneg-Mz360,interface glial cell,ventral nerve cord commissure,longitudinal connective,photoreceptor cell R7,peripheral glial cell,embryonic peripheral glial cell 6,embryonic peripheral glial cell 8,embryonic peripheral glial cell 5" FBgn0001174 halo halo http://flybase.org/reports/FBgn0001174 FBgn0031346 protein_coding_gene kinesin binding ; GO:0019894 | inferred from direct assay lipid transport ; GO:0006869 | inferred from mutant phenotype regulation of localization ; GO:0032879 | inferred from mutant phenotype lipid particle transport along microtubule ; GO:0031887 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from mutant phenotype regulation of phosphorylation ; GO:0042325 | inferred from genetic interaction with Lsd-2 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG7428, halo" IPR007970:Protein of unknown function DUF733 CG7428 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | gastrula , embryonic stage | cycle 13-14 " " organism | restricted

, organism

" viable FBgn0259629 B1112 - http://flybase.org/reports/FBgn0259629 gene - - - B1112 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "1st posterior cell,wing,anterior crossvein" FBgn0040006 CG12595 - http://flybase.org/reports/FBgn0040006 protein_coding_gene - - - CG12595 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267518 2SrRNA-Psi:CR45858 2S ribosomal RNA pseudogene:CR45858 http://flybase.org/reports/FBgn0267518 pseudogene_attribute - - - "2SrRNA-Psi:CR45858, CR45858" - CR45858 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014913 anon-4Fg anon-4Fg http://flybase.org/reports/FBgn0014913 - gene - - - anon-4Fg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262814 CG43185 - http://flybase.org/reports/FBgn0262814 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43185 - CG43185 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005580 l(1)J1674 lethal (1) J1674 http://flybase.org/reports/FBgn0005580 - gene - - - l(1)J1674 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" FBgn0053700 CG33700 - http://flybase.org/reports/FBgn0053700 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33700 IPR010512:Protein of unknown function DUF1091 CG33700 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035233 Pex10 Peroxin 10 http://flybase.org/reports/FBgn0035233 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR025654 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000002673" primary spermatocyte growth ; GO:0007285 | inferred from mutant phenotype spermatocyte division ; GO:0048137 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8851 protein import into peroxisome membrane ; GO:0045046 | NOT inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000002673 very long-chain fatty acid catabolic process ; GO:0042760 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype protein import into peroxisome matrix ; GO:0016558 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype integral component of peroxisomal membrane ; GO:0005779 | inferred from electronic annotation with InterPro:IPR025654 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8851 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with SGD:S000002673 peroxisomal membrane ; GO:0005778 | inferred from biological aspect of ancestor with PANTHER:PTN000598603 "CG7864, pex10, Pex10, DmelPex10, PEX10" "IPR025654:Peroxisome biogenesis factor 10, IPR001841:Zinc finger, RING-type, IPR006845:Pex, N-terminal, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7864 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-247l8.8, Drer\rnf20, Drer\pex10, Drer\rnf4, Drer\rnf185, Drer\rnf145b, Drer\rnf145a, Drer\mul1a" "Scer\BRE1, Scer\PEX10" "Cele\rnf-5, Cele\rfp-1, Cele\C32D5.11, Cele\Y47G6A.31, Cele\prx-10" "Xtro\rnf5, Xtro\rnf145, Xtro\pex10" "Mmus\Rnf145, Mmus\Pex10, Mmus\Rnf20, Mmus\Rnf4, Mmus\Rnf5, Mmus\Trim39, Mmus\Rnf185, Mmus\Rnf40" "Hsap\RNF20, Hsap\TRIM39, Hsap\RNF185, Hsap\RNF145, Hsap\RNF40, Hsap\PEX10, Hsap\RNF4, Hsap\RNF5, Hsap\PEX12, Hsap\LONRF2" "viable,female semi-fertile,male sterile,developmental rate defective,cytokinesis defective,meiotic cell cycle defective" "spermatid,testis" FBgn0263544 mir-4949 mir-4949 stem loop http://flybase.org/reports/FBgn0263544 miRNA_gene - - - "mir-4949, dme-mir-4949, CR43529" - CR43529 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036504 yellow-k yellow-k http://flybase.org/reports/FBgn0036504 protein_coding_gene - cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG7463, yellow-k, yell-k" "IPR011042:Six-bladed beta-propeller, TolB-like, IPR017996:Major royal jelly protein/protein yellow" CG7463 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267413 CG45766 - http://flybase.org/reports/FBgn0267413 protein_coding_gene - - - "CG45766, Mst77Y" - CG45766 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084848 l(3)S057101 l(3)S057101 http://flybase.org/reports/FBgn0084848 gene - - - l(3)S057101 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004143 nullo nullo http://flybase.org/reports/FBgn0004143 FBgn0062443 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity protein localization ; GO:0008104 | non-traceable author statement morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cleavage furrow formation ; GO:0036089 | inferred from genetic interaction with slam cell-cell junction assembly ; GO:0007043 | inferred from mutant phenotype cellularization ; GO:0007349 | traceable author statement actomyosin contractile ring assembly ; GO:0000915 | non-traceable author statement cellularization ; GO:0007349 | non-traceable author statement adherens junction ; GO:0005912 | traceable author statement cell-cell junction ; GO:0005911 | traceable author statement "nullo, CG14426, BcDNA:RE47733, Nullo" - CG14426 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | cycle 14 , embryonic stage | cycle 11-14 , embryonic stage | embryonic cycle 11..14 " " organism

,

{ 0 Sry-&agr;- } " embryonic stage | embryonic cycle 13-16 "lethal,partially,recessive,heat sensitive,wild-type,partially lethal - majority die,viable,cold sensitive" "cleavage stage embryo,spot adherens junctionmat.‘±Tub67C.THsimVP16,ventral furrow,zonula adherensmat.‘±Tub67C.THsimVP16,embryonic/first instar larval cuticle,epithelial cell | embryonic stage" FBgn0020869 anon-R100 anon-R100 http://flybase.org/reports/FBgn0020869 - gene - - - "2-R100, anon-R100" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,dominant" FBgn0052480 tRNA:Ile-TAT-1-1 transfer RNA:Isoleucine-TAT 1-1 http://flybase.org/reports/FBgn0052480 tRNA_gene AUA codon-amino acid adaptor activity ; GO:0033435 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033435 cytosol ; GO:0005829 | inferred by curator from GO:0033435 "CR32480, AE002584.trna1-IleTAT, tRNA:I:TAT:AE002584-a, chr3L.trna1-IleTAT, tRNA-Ile-TAT-1-1, tRNA:Ile-TAT-1-1, tRNA:CR32480, AUA" - CR32480 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264412 FCE-E - http://flybase.org/reports/FBgn0264412 gene - - - FCE-E - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,somatic clone" FBgn0084003 CG41436 - http://flybase.org/reports/FBgn0084003 protein_coding_gene - - - CG41436 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060443 l(3)S123206b lethal (3) S123206b http://flybase.org/reports/FBgn0060443 gene - - - "1232/06, l(3)S123206b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0035205 Ctr9 Ctr9 http://flybase.org/reports/FBgn0035205 protein_coding_gene RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000361535 SH2 domain binding ; GO:0042169 | inferred from sequence or structural similarity with MGI:MGI:109345 "regulation of histone H3-K4 methylation ; GO:0051569 | inferred from biological aspect of ancestor with PANTHER:PTN000361535 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000361535 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with MGI:MGI:109345" transcriptionally active chromatin ; GO:0035327 | inferred from sequence or structural similarity with MGI:MGI:109345 Cdc73/Paf1 complex ; GO:0016593 | inferred from biological aspect of ancestor with PANTHER:PTN000361535 "cg2469, Ctr9, CG2469" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR027363:Methylthioribose-1-phosphate isomerase-like, N-terminal domain, IPR031101:RNA polymerase-associated protein Ctr9, IPR013105:Tetratricopeptide repeat 2" CG2469 11-Aug-17 DroID_v2017_08 Drer\ctr9 Scer\CTR9 Cele\ctr-9 Xtro\ctr9 Mmus\Ctr9 Hsap\CTR9 DRSC27308 IK 1.009217821 1.785318917 1.068706652 -0.184405856 2.249199394 1.818445458 FBgn0066102 Krn::spi Krn::spi http://flybase.org/reports/FBgn0066102 engineered_fusion_gene - - - Krn::spi - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0060896 l(3)S044339 lethal (3) S044339 http://flybase.org/reports/FBgn0060896 gene - - - "0443/39, l(3)S044339" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0263620 CR43629 - http://flybase.org/reports/FBgn0263620 non_protein_coding_gene - - - CR43629 - CR43629 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026199 myo myoglianin http://flybase.org/reports/FBgn0026199 FBgn0064928 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR001839, InterPro:IPR017948 cytokine activity ; GO:0005125 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 transforming growth factor beta receptor binding ; GO:0005160 | inferred from biological aspect of ancestor with PANTHER:PTN000218063" mushroom body development ; GO:0016319 | inferred from mutant phenotype positive regulation of pathway-restricted SMAD protein phosphorylation ; GO:0010862 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 SMAD protein signal transduction ; GO:0060395 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 cell development ; GO:0048468 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 BMP signaling pathway ; GO:0030509 | inferred from biological aspect of ancestor with PANTHER:PTN000218210 regulation of MAPK cascade ; GO:0043408 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 "Myoglianin, CG1838, BcDNA:LD02307, myoglianin, MYO, Myo, myg, myo" "IPR001839:Transforming growth factor-beta, C-terminal, IPR015615:Transforming growth factor-beta-related, IPR017948:Transforming growth factor beta, conserved site, IPR029034:Cystine-knot cytokine" CG1838 11-Aug-17 DroID_v2017_08 "Drer\bmp6, Drer\bmp8a, Drer\amh, Drer\bmp10l, Drer\tgfb1a, Drer\gdf10a, Drer\spaw, Drer\gdf7, Drer\LOC100329520, Drer\inhbab, Drer\admp, Drer\tgfb3, Drer\gdf5, Drer\gdf9, Drer\gdf2, Drer\bmp3, Drer\bmp4, Drer\ndr2, Drer\inhbb, Drer\bmp7a, Drer\lft2, Drer\tgfb1b, Drer\mstna, Drer\bmp10, Drer\gdf10b, Drer\bmp7b, Drer\lft1, Drer\bmp2b, Drer\gdf11, Drer\inhbaa, Drer\mstnb, Drer\gdf6a, Drer\inha, Drer\tgfb2l, Drer\ndr1, Drer\bmp15, Drer\tgfb2, Drer\gdf3, Drer\bmp2a, Drer\gdf6b" - "Cele\dbl-1, Cele\unc-129, Cele\tig-2, Cele\daf-7" "Xtro\nodal6, Xtro\lefty, Xtro\mstn.1, Xtro\nodal, Xtro\gdf1, Xtro\gdf11.1, Xtro\bmp6, Xtro\gdf7, Xtro\bmp7.2, Xtro\inhbc.1, Xtro\bmp2, Xtro\nodal5, Xtro\tgfb2, Xtro\bmp3, Xtro\gdf3, Xtro\bmp7.1, Xtro\nodal, Xtro\bmp4, Xtro\bmp5, Xtro\admp, Xtro\inha, Xtro\bmp10, Xtro\gdf2, Xtro\gdf9, Xtro\bmp15, Xtro\nodal1, Xtro\bmp8, Xtro\gdf5, Xtro\gdf10, Xtro\tgfb1" "Mmus\Gdf1, Mmus\Gdf2, Mmus\Gdf3, Mmus\Inhba, Mmus\Inha, Mmus\Gdf9, Mmus\Bmp6, Mmus\Lefty1, Mmus\Bmp8b, Mmus\Nodal, Mmus\Bmp15, Mmus\Inhbc, Mmus\Inhbe, Mmus\Gdf11, Mmus\Inhbb, Mmus\Mstn, Mmus\Tgfb2, Mmus\Gdf10, Mmus\Bmp8a, Mmus\Bmp4, Mmus\Gdf15, Mmus\Bmp2, Mmus\Bmp10, Mmus\Gdf7, Mmus\Tgfb3, Mmus\Tgfb1, Mmus\Amh, Mmus\Gdf6, Mmus\Bmp5, Mmus\Lefty2, Mmus\Bmp3, Mmus\Bmp7, Mmus\Gdf5" "Hsap\GDF3, Hsap\INHBA, Hsap\LEFTY1, Hsap\BMP8B, Hsap\INHBC, Hsap\GDF15, Hsap\TGFB2, Hsap\AMH, Hsap\BMP15, Hsap\BMP5, Hsap\GDF1, Hsap\BMP2, Hsap\INHBB, Hsap\MSTN, Hsap\GDF11, Hsap\TGFB1, Hsap\TGFB3, Hsap\NODAL, Hsap\GDF2, Hsap\INHBE, Hsap\BMP3, Hsap\GDF9, Hsap\LEFTY2, Hsap\BMP8A, Hsap\GDF5, Hsap\INHA, Hsap\BMP10, Hsap\GDF10, Hsap\BMP7, Hsap\GDF7, Hsap\BMP4, Hsap\BMP6, Hsap\GDF6" " larval stage , embryonic stage | stage >=15 , embryonic stage | early , embryonic stage | stage 6 , embryonic stage | stage 11 , embryonic stage -- adult stage , embryonic stage | stage 14 " " glial cell

, embryonic/larval visceral muscle

, pole plasm

, pole cell

, glioblast

, visceral muscle &&of embryonic heart

, embryonic/larval somatic muscle

" "developmental rate defective,recessive,neuroanatomy defective,lethal,majority die during larval stage,viable,cell growth defective,circadian rhythm defective,heat sensitive" "gamma Kenyon cell,adult mushroom body,wing,embryonic/larval neuromuscular junction | larval stage,transverse nerve" FBgn0034106 CG9068 - http://flybase.org/reports/FBgn0034106 protein_coding_gene - - - CG9068 "IPR013594:Dynein heavy chain, domain-1" CG9068 11-Aug-17 DroID_v2017_08 "Drer\dnah2, Drer\si:dkeyp-86b9.1, Drer\dnah9" - - Xtro\dnah2 "Mmus\Dnah2, Mmus\Dnah10" "Hsap\DNAH10, Hsap\C8orf44, Hsap\DNAH2" viable FBgn0038912 CG6656 - http://flybase.org/reports/FBgn0038912 protein_coding_gene acid phosphatase activity ; GO:0003993 | inferred from sequence or structural similarity with HGNC:125 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:125 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:125 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:125 CG6656 "IPR000560:Histidine phosphatase superfamily, clade-2, IPR029033:Histidine phosphatase superfamily" CG6656 11-Aug-17 DroID_v2017_08 "Drer\acp6, Drer\pxylp1, Drer\acp2" - "Cele\pho-5, Cele\acp-2, Cele\pho-6, Cele\pho-12, Cele\pho-11, Cele\pho-1, Cele\acp-7, Cele\acp-4, Cele\pho-13, Cele\pho-10, Cele\F26C11.1, Cele\ZK792.1, Cele\acp-1, Cele\acp-5, Cele\ZK809.9, Cele\pho-7, Cele\pho-14, Cele\pho-8, Cele\C27A2.12, Cele\pho-9, Cele\acp-3, Cele\pho-4, Cele\acp-6" "Xtro\LOC100494856, Xtro\acp2, Xtro\acp6" "Mmus\Acp2, Mmus\Acpp, Mmus\Acpt, Mmus\Acp6, Mmus\Pxylp1" "Hsap\ACP2, Hsap\PXYLP1, Hsap\ACPT, Hsap\ACPP, Hsap\ACP6" viable FBgn0041619 SM2-1 SM2-1 http://flybase.org/reports/FBgn0041619 gene - - - SM2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266964 CR45415 - http://flybase.org/reports/FBgn0266964 non_protein_coding_gene - - - CR45415 - CR45415 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034267 CG4984 - http://flybase.org/reports/FBgn0034267 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004031 CG4984 IPR004031:PMP-22/EMP/MP20/Claudin superfamily CG4984 11-Aug-17 DroID_v2017_08 "Drer\cacng7a, Drer\lim2.2, Drer\gsg1l2b, Drer\lim2.5, Drer\cacng5b, Drer\emp1, Drer\emp3b, Drer\gsg1l, Drer\pmp22b, Drer\emp2, Drer\si:dkey-264d12.4, Drer\si:ch211-232m10.6, Drer\pmp22a, Drer\si:ch211-149k23.9, Drer\cacng5a, Drer\lim2.4, Drer\lim2.3, Drer\lim2.1" - "Cele\clc-2, Cele\clc-5, Cele\nsy-4, Cele\K10D6.2, Cele\clc-1, Cele\C46C11.3" Xtro\tmem114 "Mmus\Emp3, Mmus\Pmp22, Mmus\Gsg1, Mmus\Gsg1l2, Mmus\Emp2, Mmus\Tmem114, Mmus\Lim2, Mmus\Gsg1l, Mmus\Emp1, Mmus\Odf4, Mmus\Cldnd2, Mmus\Tmem202, Mmus\Tmem235, Mmus\Nkg7" "Hsap\EMP2, Hsap\CLDND2, Hsap\CACNG3, Hsap\NKG7, Hsap\EMP3, Hsap\CACNG8, Hsap\GSG1L, Hsap\CACNG4, Hsap\GSG1L2, Hsap\CACNG7, Hsap\GSG1, Hsap\ODF4, Hsap\TMEM202, Hsap\PMP22, Hsap\EMP1, Hsap\CACNG2, Hsap\LIM2, Hsap\CACNG5" "viable,visible" "chaeta,supernumerary" DRSC06908 K -0.371250086 0.270635387 0.01322685 0.124959741 1.528127654 -0.385284918 FBgn0037050 ICA69 ICA69 http://flybase.org/reports/FBgn0037050 protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from electronic annotation with InterPro:IPR010504 molecular_function ; GO:0003674 | no biological data available regulation of neurotransmitter secretion ; GO:0046928 | inferred from electronic annotation with InterPro:IPR024116 biological_process ; GO:0008150 | no biological data available Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity with HGNC:5343 "Dm ric-19, dCG10566-PA, ICA69, CG10566, ICA-69" "IPR010504:Arfaptin homology (AH) domain, IPR024114:Islet cell autoantigen 1/Ica1-like, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR024116:Resistance to inhibitors of cholinesterase protein 19, IPR006723:Islet cell autoantigen Ica1, C-terminal" CG10566 11-Aug-17 DroID_v2017_08 "Drer\ical1, Drer\ica1" - Cele\ric-19 Xtro\ica1 "Mmus\Ica1, Mmus\Ica1l" "Hsap\ICA1, Hsap\ICA1L" viable FBgn0058466 CG40466 - http://flybase.org/reports/FBgn0058466 protein_coding_gene - - - CG40466 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052376 CG32376 - http://flybase.org/reports/FBgn0052376 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP148, CG8528, CG32376" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG32376 11-Aug-17 DroID_v2017_08 Drer\si:dkey-21e2.13 - Cele\try-1 "Xtro\prtn3, Xtro\gzma" "Mmus\Prss57, Mmus\Klk1b16, Mmus\Prss53, Mmus\Prss36, Mmus\Prss55, Mmus\Gzmk" "Hsap\GZMK, Hsap\PRSS53, Hsap\CMA1, Hsap\PRSS57, Hsap\PRSS36" "viable,fertile" FBgn0039472 CG17192 - http://flybase.org/reports/FBgn0039472 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG17192, DmelL5" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG17192 11-Aug-17 DroID_v2017_08 "Drer\lipca, Drer\lipib, Drer\LOC100331214, Drer\lipia, Drer\lipg, Drer\LOC101884800, Drer\lpl, Drer\pla1a" - - "Xtro\lipg, Xtro\lpl" "Mmus\Lipg, Mmus\Pla1a, Mmus\Pnlip, Mmus\Liph, Mmus\Pnliprp1, Mmus\Lipi, Mmus\Lpl, Mmus\Pnliprp2, Mmus\Lipc" "Hsap\LIPG, Hsap\PNLIP, Hsap\LIPH, Hsap\LIPI, Hsap\LIPC, Hsap\PNLIPRP2, Hsap\PNLIPRP1, Hsap\PNLIPRP3, Hsap\LPL, Hsap\PLA1A" viable FBgn0035273 CG12020 - http://flybase.org/reports/FBgn0035273 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR008971 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971 - CG12020 "IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding" CG12020 11-Aug-17 DroID_v2017_08 "Drer\dnajc18, Drer\dnajb12a, Drer\dnajb5, Drer\dnajb9a, Drer\dnajb1b, Drer\dnajb12b, Drer\dnajb2, Drer\dnajb13, Drer\dnajc4, Drer\dnaja2, Drer\dnajc7, Drer\dnaja2l, Drer\dnaja1, Drer\dnajb4, Drer\dnajc22, Drer\dnajb1a, Drer\dnajb14" "Scer\MDJ1, Scer\XDJ1, Scer\YDJ1, Scer\SIS1, Scer\HLJ1, Scer\DJP1" "Cele\dnj-16, Cele\dnj-17, Cele\dnj-18" "Xtro\dnajb9, Xtro\dnajb12, Xtro\dnajc22, Xtro\dnajb5, Xtro\dnajb4, Xtro\dnajb1, Xtro\dnajb2, Xtro\dnaja2, Xtro\dnajc18, Xtro\dnaja1, Xtro\dnajb14, Xtro\dnaja4.1, Xtro\dnajb13, Xtro\dnaja4.2, Xtro\dnajb6" "Mmus\Dnaja1, Mmus\Dnajb8, Mmus\4930503B20Rik, Mmus\Dnaja2, Mmus\Dnajb3, Mmus\Dnajb5, Mmus\Dnajc22, Mmus\Dnajb14, Mmus\Dnajb2, Mmus\Dnajb9, Mmus\Dnajb13, Mmus\Dnajc21, Mmus\Dnajb6, Mmus\Dnajc7, Mmus\Dnaja4, Mmus\Dnajb12, Mmus\Dnajc18, Mmus\Dnajc4, Mmus\Dnajb1, Mmus\Dnajb4, Mmus\Dnajb7" "Hsap\DNAJB4, Hsap\DNAJB12, Hsap\DNAJC22, Hsap\DNAJA2, Hsap\DNAJB9, Hsap\DNAJC4, Hsap\DNAJA1, Hsap\DNAJB13, Hsap\DNAJB5, Hsap\DNAJB1, Hsap\DNAJC18, Hsap\DNAJB2, Hsap\DNAJB7, Hsap\DNAJC7, Hsap\DNAJB14, Hsap\DNAJB6, Hsap\DNAJA4, Hsap\DNAJB8" viable FBgn0039810 CG15549 - http://flybase.org/reports/FBgn0039810 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BcDNA:AT07554, CG15549" - CG15549 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0002256 l(3)68Fa lethal (3) 68Fa http://flybase.org/reports/FBgn0002256 - gene - - - "rsg18, l(3)rsg18, l(3)V4-5, l(3)F11, l(3)68Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060346 l(3)S143301b lethal (3) S143301b http://flybase.org/reports/FBgn0060346 gene - - - "1433/01, l(3)S143301b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265498 CR44367 - http://flybase.org/reports/FBgn0265498 non_protein_coding_gene - - - CR44367 - CR44367 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011628 l(2)T57a18 lethal (2) T57a18 http://flybase.org/reports/FBgn0011628 FBgn0005177 gene - - - l(2)T57a18 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262463 mir-100 mir-100 stem loop http://flybase.org/reports/FBgn0262463 miRNA_gene - cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype - "miR-100, dme-mir-100, mir-100, Dme-miR-100, CR43044, CR33313, dme-miR-100" - CR43044 11-Aug-17 DroID_v2017_08 - - - - - - prepupal stage--adult stage FBgn0028253 l(3)84Ch lethal (3) 84Ch http://flybase.org/reports/FBgn0028253 gene - - - l(3)84Ch - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058294 CG40294 - http://flybase.org/reports/FBgn0058294 protein_coding_gene - - - CG40294 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061088 l(3)S011524 lethal (3) S011524 http://flybase.org/reports/FBgn0061088 gene - - - "0682/12, 0115/24, l(3)S068212, l(3)S011524" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0264431 CR43849 - http://flybase.org/reports/FBgn0264431 non_protein_coding_gene - - - CR43849 - CR43849 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051785 CG31785 - http://flybase.org/reports/FBgn0051785 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31785 - CG31785 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0024364 CG11417 - http://flybase.org/reports/FBgn0024364 - protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012580 "EG:8D8.4, CG11417" IPR012580:NUC153 CG11417 11-Aug-17 DroID_v2017_08 Drer\esf1 Scer\ESF1 Cele\F58B3.4 Xtro\esf1 Mmus\Esf1 Hsap\ESF1 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0013611 l(3)EX-G13 lethal (3) EX-G13 http://flybase.org/reports/FBgn0013611 - gene - - - l(3)EX-G13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001200 His4 Histone H4 http://flybase.org/reports/FBgn0001200 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072" "female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR019809 DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823" "RCAF complex ; GO:0035059 | inferred from direct assay nucleosome ; GO:0000786 | traceable author statement nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 chromosome ; GO:0005694 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay" "H4, H4Ac16, HisC, Bin2, his4, 4, DmeH4, His4, histone, his, dH4, H4_DROME, H4K20" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" - 11-Aug-17 DroID_v2017_08 - - - - - - " egg stage | fertilized egg , adult stage " " male pronucleus

, spermatozoon

, spermatid | late

, spermatid | early

, female pronucleus

" "meiotic cell cycle defective,dominant" FBgn0003725 tms tumorous http://flybase.org/reports/FBgn0003725 - gene - - - tms - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" FBgn0067764 l(1)16-3-98 lethal (1) 16-3-98 http://flybase.org/reports/FBgn0067764 gene - - - l(1)16-3-98 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060645 l(3)S084013b lethal (3) S084013b http://flybase.org/reports/FBgn0060645 gene - - - "0840/13, l(3)S084013b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083281 E(smoDN)2243 Enhancer of smoDN 2243 http://flybase.org/reports/FBgn0083281 gene - - - E(smoDN)2243 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033826 CG4734 - http://flybase.org/reports/FBgn0033826 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4734 IPR000859:CUB domain CG4734 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267591 CR45929 - http://flybase.org/reports/FBgn0267591 non_protein_coding_gene - - - CR45929 - CR45929 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014954 dl::zen2 dl::zen2 http://flybase.org/reports/FBgn0014954 - engineered_fusion_gene - - - dl::zen2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021757 bub bubblewing http://flybase.org/reports/FBgn0021757 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "2L-A, bub" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone" FBgn0051445 CG31445 - http://flybase.org/reports/FBgn0051445 protein_coding_gene peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "CG11955, CG31445" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG31445 11-Aug-17 DroID_v2017_08 "Drer\lnpep, Drer\anpepa, Drer\enpep, Drer\erap1b, Drer\anpepb, Drer\si:ch211-198g19.1, Drer\erap1a, Drer\npepps, Drer\si:ch211-149p5.1, Drer\erap2, Drer\si:ch211-106j24.1, Drer\si:ch211-276a23.5" "Scer\AAP1, Scer\APE2, Scer\TMA108" "Cele\Y67D8C.9, Cele\T07F10.1, Cele\T16G12.1, Cele\AC3.5, Cele\pam-1, Cele\T12E12.6, Cele\R03G8.4, Cele\Y42A5A.1, Cele\VB0395L.1, Cele\R03G8.6, Cele\F49B2.6, Cele\Y53F4B.20, Cele\mnp-1" "Xtro\anpep, Xtro\enpep, Xtro\erap1, Xtro\npepps, Xtro\lnpep, Xtro\lvrn" "Mmus\Lnpep, Mmus\Enpep, Mmus\Erap1, Mmus\Trhde, Mmus\Lvrn, Mmus\Anpep, Mmus\Npepps" "Hsap\TRHDE, Hsap\ERAP1, Hsap\ANPEP, Hsap\LNPEP, Hsap\ENPEP, Hsap\NPEPPS, Hsap\LVRN, Hsap\ERAP2" FBgn0260475 CG30059 - http://flybase.org/reports/FBgn0260475 protein_coding_gene N-acetylglucosamine-6-sulfatase activity ; GO:0008449 | inferred from electronic annotation with InterPro:IPR012251 glycosaminoglycan metabolic process ; GO:0030203 | inferred from electronic annotation with InterPro:IPR012251 - "anon-WO0140519.22, CG30059" "IPR000917:Sulfatase, N-terminal, IPR012251:N-acetylglucosamine-6-sulfatase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site" CG30059 11-Aug-17 DroID_v2017_08 "Drer\sulf2a, Drer\arsk, Drer\sulf2b, Drer\gnsb, Drer\gnsa, Drer\sulf1" - Cele\sul-1 "Xtro\gns, Xtro\sulf2, Xtro\arsk, Xtro\sulf1" "Mmus\Arsk, Mmus\Sulf2, Mmus\Sulf1, Mmus\Gns" "Hsap\ARSK, Hsap\SULF2, Hsap\GNS, Hsap\SULF1" viable FBgn0023222 E(Egfr)C22 Enhancer of Egfr C22 http://flybase.org/reports/FBgn0023222 - gene - - - E(Egfr)C22 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038921 CG6332 - http://flybase.org/reports/FBgn0038921 protein_coding_gene - - - "anon-WO0140519.231, CG6332, cg6332" IPR006623:Testicular haploid expressed repeat CG6332 11-Aug-17 DroID_v2017_08 Drer\theg - - - "Mmus\Theg, Mmus\Thegl" "Hsap\THEGL, Hsap\THEG" viable FBgn0034092 CG7798 - http://flybase.org/reports/FBgn0034092 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 - - CG7798 "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR023346:Lysozyme-like domain, IPR019799:Glycoside hydrolase, family 22, conserved site" CG7798 11-Aug-17 DroID_v2017_08 "Drer\LOC100334363, Drer\lyz, Drer\LOC100536671" - - Xtro\MGC89221 "Mmus\Lyzl6, Mmus\Spaca7, Mmus\Spaca1, Mmus\Spaca5, Mmus\Spaca3, Mmus\Lyz1, Mmus\9530003J23Rik, Mmus\1700016D06Rik, Mmus\Lyz2, Mmus\Lalba, Mmus\Spaca4, Mmus\Lyzl1, Mmus\Lyzl4" "Hsap\LYZL1, Hsap\LALBA, Hsap\LYZ, Hsap\SPACA7, Hsap\SPACA4, Hsap\SPACA1, Hsap\SPACA5, Hsap\SPACA5B, Hsap\LYZL4, Hsap\SPACA3, Hsap\LYZL6, Hsap\LYZL2" FBgn0085548 CG40972 - http://flybase.org/reports/FBgn0085548 protein_coding_gene - - - CG40972 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020180 Dfd::ro Dfd::ro http://flybase.org/reports/FBgn0020180 - engineered_fusion_gene - - - Dfd::ro - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033087 Hsepi Heparan sulfate C5-epimerase http://flybase.org/reports/FBgn0033087 protein_coding_gene "racemase and epimerase activity, acting on carbohydrates and derivatives ; GO:0016857 | inferred from electronic annotation with InterPro:IPR010598" glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from electronic annotation with InterPro:IPR010598 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010598 "CG3194, Hsepi" IPR010598:D-glucuronyl C5-epimerase CG3194 11-Aug-17 DroID_v2017_08 "Drer\glceb, Drer\glcea" - Cele\hse-5 Xtro\glce Mmus\Glce Hsap\GLCE "viable,partially lethal - majority die,fertile,increased mortality during development,short lived" "posterior crossvein,wing vein,wing sensillum,wing vein L5" FBgn0003315 satDNA satellite DNA http://flybase.org/reports/FBgn0003315 - satellite_DNA - - - "SAR-DM, 1.688, stDNA, sc1, satDNA, SATI, SATIII, microsatellite, SSR, 1.686, SatIII, MSs, SAT III" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065399 l(2)SH1605 lethal (2) SH1605 http://flybase.org/reports/FBgn0065399 gene - - - "l(2)SH1605, l(2)SH2 1605" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265830 CR44619 - http://flybase.org/reports/FBgn0265830 non_protein_coding_gene - - - "lincRNA.984, CR44619" - CR44619 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083301 E(smoDN)1736 Enhancer of smoDN 1736 http://flybase.org/reports/FBgn0083301 gene - - - E(smoDN)1736 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020908 Scp1 Sarcoplasmic calcium-binding protein 1 http://flybase.org/reports/FBgn0020908 "FBgn0039982, FBgn0063247, FBan0015848" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "Dcabp-A.1, BcDNA:GH15296, CG15848, Scp1, SCP" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG15848 11-Aug-17 DroID_v2017_08 - - "Cele\cex-2, Cele\cex-1" - - - adult stage mesothoracic extracoxal depressor muscle 66 | restricted

DRSC20806 K 0.450544992 -0.222693531 0.704376164 0.44088234 0.128092375 1.677009178 FBgn0004584 Rrp1 Recombination repair protein 1 http://flybase.org/reports/FBgn0004584 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR020847, InterPro:IPR020848 double-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008311 | inferred from biological aspect of ancestor with PANTHER:PTN000507731 3'-5' exonuclease activity ; GO:0008408 | inferred from direct assay DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906 | inferred from direct assay" base-excision repair ; GO:0006284 | inferred from biological aspect of ancestor with PANTHER:PTN000507731 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000507732 "Rrp1, RRP1, rrp, CG3178, Rrp-1, 3178, RRP1_DROME" "IPR004808:AP endonuclease 1, IPR005135:Endonuclease/exonuclease/phosphatase, IPR020847:AP endonuclease 1, binding site, IPR020848:AP endonuclease 1, conserved site" CG3178 11-Aug-17 DroID_v2017_08 "Drer\apex1, Drer\apex2" "Scer\APN2, Scer\SRP40" Cele\exo-3 "Xtro\apex2, Xtro\apex1, Xtro\nolc1" "Mmus\Nolc1, Mmus\Apex2, Mmus\Apex1" "Hsap\NOLC1, Hsap\APEX1, Hsap\APEX2" " embryonic stage | early , adult stage | female " viable DRSC26575 IK -1.895582074 -0.475131465 -0.366809517 -0.173639136 0.097521337 2.397591801 FBgn0013503 l(1)PB7 lethal (1) PB7 http://flybase.org/reports/FBgn0013503 - gene - - - l(1)PB7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0270927 betaGlu beta glucuronidase http://flybase.org/reports/FBgn0270927 protein_coding_gene beta-glucuronidase activity ; GO:0004566 | inferred from direct assay carbohydrate metabolic process ; GO:0005975 | inferred from biological aspect of ancestor with PANTHER:PTN000007197 intrinsic component of membrane ; GO:0031224 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000007197 "betaGlu, beta-GUS, Glc, Glu, gus, CG2135" "IPR013783:Immunoglobulin-like fold, IPR006101:Glycoside hydrolase, family 2, IPR006102:Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich, IPR006103:Glycoside hydrolase family 2, catalytic domain, IPR006104:Glycosyl hydrolases family 2, sugar binding domain, IPR008979:Galactose-binding domain-like, IPR017853:Glycoside hydrolase superfamily, IPR023230:Glycoside hydrolase, family 2, conserved site" CG2135 11-Aug-17 DroID_v2017_08 Drer\gusb - Cele\Y105E8B.9 Xtro\gusb Mmus\Gusb Hsap\GUSB viable FBgn0033970 CG10205 - http://flybase.org/reports/FBgn0033970 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT28709, CG10205" - CG10205 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060331 l(3)S145701a lethal (3) S145701a http://flybase.org/reports/FBgn0060331 gene - - - "1457/01, l(3)S145701a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0014263 oho55DE overgrown hematopoietic organs 55DE http://flybase.org/reports/FBgn0014263 - gene molecular_function ; GO:0003674 | no biological data available lymph gland development ; GO:0048542 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)k13104, l(2)30/7, oho55D,E, l(2)k03007, oho55DE" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,hyperplasia,recessive" "embryonic/larval brain,embryonic/larval lymph gland" FBgn0261361 CG42638 - http://flybase.org/reports/FBgn0261361 protein_coding_gene - - - "CG42638, noncoding_13567" "IPR013122:Polycystin cation channel, PKD1/PKD2" CG42638 11-Aug-17 DroID_v2017_08 "Drer\mcoln3a, Drer\mcoln3b, Drer\mcoln1a, Drer\mcoln2, Drer\mcoln1b" - Cele\cup-5 "Xtro\mcoln3, Xtro\mcoln1, Xtro\mcoln2, Xtro\LOC101734792" "Mmus\Mcoln2, Mmus\Mcoln1, Mmus\Mcoln3" "Hsap\MCOLN1, Hsap\MCOLN2, Hsap\MCOLN3" FBgn0037063 CG9391 - http://flybase.org/reports/FBgn0037063 protein_coding_gene inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from sequence or structural similarity with HGNC:6051 inositol monophosphate 1-phosphatase activity ; GO:0008934 | non-traceable author statement inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550, InterPro:IPR020552 inositol metabolic process ; GO:0006020 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol phosphate dephosphorylation ; GO:0046855 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 dephosphorylation ; GO:0016311 | non-traceable author statement signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol phosphate dephosphorylation ; GO:0046855 | inferred from sequence or structural similarity with HGNC:6051" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6051 "142335_at, IMP, CG9391" "IPR000760:Inositol monophosphatase-like, IPR033942:Inositol monophosphatase, IPR020550:Inositol monophosphatase, conserved site, IPR020552:Inositol monophosphatase, Lithium-sensitive, IPR020583:Inositol monophosphatase, metal-binding site" CG9391 11-Aug-17 DroID_v2017_08 "Drer\impa2, Drer\impa1" "Scer\INM1, Scer\INM2" Cele\ttx-7 "Xtro\impa2, Xtro\impa1" "Mmus\Impa2, Mmus\Impa1" "Hsap\IMPA1, Hsap\IMPA2" "viable,fertile" FBgn0039348 Npl4 Nuclear protein localization 4 http://flybase.org/reports/FBgn0039348 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KN62 ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000295423 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000295423 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to virus ; GO:0098586 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "Npl4, dNp14, CG4673, npl4, NPL4, dNpl4, dNPLOC4" "IPR001876:Zinc finger, RanBP2-type, IPR007716:NPL4, zinc-binding putative, IPR007717:Nuclear pore localisation protein NPL4, C-terminal, IPR016563:Nuclear protein localization protein 4, IPR024682:Nuclear pore localisation protein Npl4, ubiquitin-like domain, IPR029071:Ubiquitin-related domain" CG4673 11-Aug-17 DroID_v2017_08 Drer\nploc4 Scer\NPL4 "Cele\npl-4.1, Cele\npl-4.2" Xtro\nploc4 Mmus\Nploc4 Hsap\NPLOC4 "lethal,neuroanatomy defective,stress response defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0032047 CG13088 - http://flybase.org/reports/FBgn0032047 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG13088, FBXO15" "IPR032675:Leucine-rich repeat domain, L domain-like" CG13088 11-Aug-17 DroID_v2017_08 - - Cele\B0393.3 - - - viable FBgn0033821 CG10799 - http://flybase.org/reports/FBgn0033821 protein_coding_gene - - - "CT30256, CG10799" - CG10799 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0044063 GTD74-1 GTD74-1 http://flybase.org/reports/FBgn0044063 gene - - - GTD74-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041239 Gr58a Gustatory receptor 58a http://flybase.org/reports/FBgn0041239 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "CG30396, Gr58A1, 58A1, 58A.1, GR58A.1, Gr58a" IPR013604:7TM chemoreceptor CG30396 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267938 CR46218 - http://flybase.org/reports/FBgn0267938 non_protein_coding_gene - - - "CR46218, lincRNA.764" - CR46218 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062668 EP3085 EP3085 http://flybase.org/reports/FBgn0062668 gene - - - "EP(3)3085, EP3085" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043890 l(3)C101 lethal (3) C101 http://flybase.org/reports/FBgn0043890 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available l(3)C101 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040219 fs(2)BG07 fs(2)BG07 http://flybase.org/reports/FBgn0040219 gene - - - fs(2)BG07 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0022405 Est-10 Esterase 10 http://flybase.org/reports/FBgn0022405 - gene - - - "EST-10, Est-10" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035726 CG9953 - http://flybase.org/reports/FBgn0035726 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR008758 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008758 - CG9953 "IPR008758:Peptidase S28, IPR029058:Alpha/Beta hydrolase fold" CG9953 11-Aug-17 DroID_v2017_08 "Drer\prss16, Drer\prss16" - "Cele\pcp-4, Cele\pcp-3, Cele\F19C7.4, Cele\F56F10.1, Cele\C26B9.5, Cele\F19C7.2, Cele\pcp-1, Cele\pcp-2, Cele\K12H4.7, Cele\F28E10.5" "Xtro\LOC100145763, Xtro\prss16" Mmus\Prss16 Hsap\PRSS16 viable FBgn0004140 fs(2)43Ei female sterile (2) 43Ei http://flybase.org/reports/FBgn0004140 FBgn0014247 gene - - - fs(2)43Ei - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile abdominal tergite marginal bristle FBgn0020577 anon-59Ch anon-59Ch http://flybase.org/reports/FBgn0020577 - gene - - - anon-59Ch - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011282 Obp84a Odorant-binding protein 84a http://flybase.org/reports/FBgn0011282 - protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 pheromone binding ; GO:0005550 | inferred from sequence or structural similarity odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "Obp84a, PBPRP-4, 84a, PBP4, PBPRP4, pbprp-4, CG1176, DmelObp84a, Pbprp4, pbprp4" IPR006170:Pheromone/general odorant binding protein CG1176 11-Aug-17 DroID_v2017_08 - - - - - - adult stage sensillum trichodeum of antennal segment 3 | subset

FBgn0000307 chif chiffon http://flybase.org/reports/FBgn0000307 FBgn0028842 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006572 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006572 protein kinase activator activity ; GO:0030295 | inferred from direct assay eggshell chorion assembly ; GO:0007306 | non-traceable author statement positive regulation of DNA replication ; GO:0045740 | inferred from mutant phenotype positive regulation of protein kinase activity ; GO:0045860 | inferred from direct assay chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype Dbf4-dependent protein kinase complex ; GO:0031431 | inferred from direct assay "Dbf4, BG:DS09218.2, BG:DS09218.1, fs(2)chiffon, CG5817, DS09218.1, chf, CG5813, chif, Chif" "IPR006572:Zinc finger, DBF-type, IPR001357:BRCT domain" CG5813 11-Aug-17 DroID_v2017_08 "Drer\dbf4, Drer\dbf4b" Scer\DBF4 - "Xtro\dbf4b, Xtro\dbf4" Mmus\Dbf4 "Hsap\DBF4, Hsap\DBF4B" " adult stage && oogenesis stage , adult stage && oogenesis stage | stage S10-11 , embryonic stage | early , adult stage && oogenesis stage | stage S13-14 " " nurse cell

, follicle cell

" "female sterile,wild-type,recessive,visible,viable" "chorion,eye,scutellar bristle,trichogen cell" FBgn0030597 Eo Ecdysone oxidase http://flybase.org/reports/FBgn0030597 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 ecdysone oxidase activity ; GO:0047875 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysone metabolic process ; GO:0008205 | inferred from direct assay" - "DmEO, CG9504, Eo, EObeta1, EO" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9504 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0034104 CG15705 - http://flybase.org/reports/FBgn0034104 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available protein phosphatase type 1 complex ; GO:0000164 | colocalizes_with inferred from direct assay CG15705 - CG15705 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053985 CG33985 - http://flybase.org/reports/FBgn0053985 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG17014, CG7973, CG33985, FBgn0036507" IPR002557:Chitin binding domain CG33985 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\C39D10.7, Cele\cpg-1, Cele\cpg-2" - - - FBgn0021862 l(2)k14206 lethal (2) k14206 http://flybase.net/reports/FBgn0021862.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" crystal cell FBgn0084702 G87 G87 http://flybase.org/reports/FBgn0084702 gene - - - G87 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040543 CG14699 - http://flybase.org/reports/FBgn0040543 protein_coding_gene - - - CG14699 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030456 CG4332 - http://flybase.org/reports/FBgn0030456 protein_coding_gene - apoptotic process ; GO:0006915 | inferred from electronic annotation with InterPro:IPR030434 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000482304 endomembrane system ; GO:0012505 | inferred from direct assay CG4332 "IPR030434:Cleft lip and palate transmembrane protein 1-like protein, IPR008429:Cleft lip and palate transmembrane 1" CG4332 11-Aug-17 DroID_v2017_08 "Drer\clptm1, Drer\clptm1l" - "Cele\C36B7.6, Cele\T13H5.8, Cele\R166.2" Xtro\clptm1l "Mmus\Clptm1, Mmus\Clptm1l" "Hsap\CLPTM1, Hsap\CLPTM1L" viable FBgn0051108 CG31108 - http://flybase.org/reports/FBgn0051108 protein_coding_gene - cellular protein modification process ; GO:0006464 | inferred from electronic annotation with InterPro:IPR004344 - "CG10057, CG31108" IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase CG31108 11-Aug-17 DroID_v2017_08 "Drer\ttll4, Drer\ttll10, Drer\ttl, Drer\ttll5, Drer\ttll2, Drer\ttll1, Drer\ttll9" Scer\PBY1 "Cele\ttll-9, Cele\ttll-5, Cele\ttll-4" "Xtro\ttll2, Xtro\ttll1, Xtro\LOC100158544, Xtro\ttl, Xtro\ttll3, Xtro\ttll5" "Mmus\Ttll2, Mmus\Ttll4, Mmus\Ttll1, Mmus\Ttll5, Mmus\Ttll10, Mmus\Ttll8, Mmus\Ttll3, Mmus\Ttll9, Mmus\Ttl" "Hsap\ARPC4-TTLL3, Hsap\TTLL8, Hsap\TTLL2, Hsap\TTLL3, Hsap\TTLL5, Hsap\TTL, Hsap\TTLL9, Hsap\TTLL10, Hsap\TTLL1, Hsap\TTLL4" FBgn0035875 Cpr66Cb Cuticular protein 66Cb http://flybase.org/reports/FBgn0035875 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr66Cb, CG7076, DmelCpr66Cb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG7076 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0016964 vm1 visible mutation-1 http://flybase.org/reports/FBgn0016964 - gene - - - vm1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0262786 CG43167 - http://flybase.org/reports/FBgn0262786 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43167 - CG43167 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265917 CR44706 - http://flybase.org/reports/FBgn0265917 pseudogene_attribute - - - "lincRNA.143, CG44706, CR44706" - CR44706 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030780 CG13008 - http://flybase.org/reports/FBgn0030780 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13009, CG13008" - CG13008 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19527 K -0.546601767 0.239391157 0.750980368 -0.394071535 -1.160765221 -1.680958718 FBgn0000966 fs(2)eo1 female sterile (2) eo1 http://flybase.org/reports/FBgn0000966 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "fs(2)eoPV30, fs(2)eo-D, fs(2)eo1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male sterile" FBgn0019906 anon-14Bd anon-14Bd http://flybase.org/reports/FBgn0019906 - gene - - - anon-14Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032961 CG1416 - http://flybase.org/reports/FBgn0032961 protein_coding_gene ATPase activator activity ; GO:0001671 | inferred from electronic annotation with InterPro:IPR015310 chaperone binding ; GO:0051087 | inferred from electronic annotation with InterPro:IPR015310 response to stress ; GO:0006950 | inferred from electronic annotation with InterPro:IPR013538 - CG1416 "IPR023393:START-like domain, IPR013538:Activator of Hsp90 ATPase homologue 1-like, IPR015310:Activator of Hsp90 ATPase, N-terminal" CG1416 11-Aug-17 DroID_v2017_08 "Drer\ahsa1a, Drer\ahsa1b" "Scer\HCH1, Scer\AHA1" Cele\C01G10.8 Xtro\ahsa1 "Mmus\Ahsa2, Mmus\Ahsa1" "Hsap\AHSA1, Hsap\AHSA2" viable FBgn0082328 HM857 HM857 http://flybase.org/reports/FBgn0082328 gene - - - HM857 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060538 l(3)S100309b lethal (3) S100309b http://flybase.org/reports/FBgn0060538 gene - - - "1003/09, l(3)S100309b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030352 sicily severe impairment of CI with lengthened youth http://flybase.org/reports/FBgn0030352 protein_coding_gene transferase activity ; GO:0016740 | inferred from electronic annotation with InterPro:IPR002060 biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR002060 mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from biological aspect of ancestor with PANTHER:PTN000475978 protein stabilization ; GO:0050821 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "sicily, XE07, CG15738" "IPR002060:Squalene/phytoene synthase, IPR008949:Isoprenoid synthase domain" CG15738 11-Aug-17 DroID_v2017_08 Drer\ndufaf6 - Cele\B0334.5 Xtro\ndufaf6 Mmus\Ndufaf6 Hsap\NDUFAF6 "neurophysiology defective,progressive,somatic clone,lethal - all die during pupal stage,viable" "mitochondrion | progressive | somatic clone,rhabdomere | progressive | somatic clone,retinal pigment cell,somatic clone,eye photoreceptor cell,progressive" FBgn0016628 E(gl)2D Enhancer of glass 2D http://flybase.org/reports/FBgn0016628 - gene - - - E(gl)2D - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" rhabdomere FBgn0067741 l(1)G0304 lethal (1) G0304 http://flybase.org/reports/FBgn0067741 gene - - - l(1)G0304 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0036093 CG14154 - http://flybase.org/reports/FBgn0036093 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14154 IPR027831:Domain of unknown function DUF4485 CG14154 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023175 Prosalpha7 Proteasome alpha7 subunit http://flybase.org/reports/FBgn0023175 - protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426 microtubule associated complex ; GO:0005875 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay" "alpha7, Prosalpha7, alpha7_dm, CG1519, CPalpha7, 1519, PSA3_DROME, Alpha7, Alpha-7, PROSalpha7, alpha-7" "IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR023332:Proteasome alpha-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG1519 11-Aug-17 DroID_v2017_08 Drer\psma3 Scer\PRE10 Cele\pas-7 Xtro\psma3 Mmus\Psma3 Hsap\PSMA3 "lethal,female sterile,meiotic cell cycle defective,male limited" "testis,spermatocyte" DRSC07516 IEK -2.369788221 -1.831585002 -1.59495144 -1.149419065 2.36275368 1.404835938 FBgn0047038 ND-13B NADH dehydrogenase (ubiquinone) 13 kDa B subunit http://flybase.org/reports/FBgn0047038 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:Q16718 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:Q16718" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:Q16718 "BcDNA:RH11203, NUFM, ND-13B, CG6463" IPR006806:ETC complex I subunit CG6463 11-Aug-17 DroID_v2017_08 Drer\ndufa5 - Cele\C33A12.1 Xtro\ndufa5 Mmus\Ndufa5 Hsap\NDUFA5 "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0064117 SLIRP1 SRA stem-loop interacting RNA binding protein 1 http://flybase.org/reports/FBgn0064117 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "CG1704, cg1704, CG33071, CG33071-ORFA, Dromel_CG33713_FBtr0091704_uORF, CG33071ORFA, SLIRP1, DmSLIRP1, CG33714" "IPR000504:RNA recognition motif domain, IPR034152:SLIRP, RNA recognition motif" CG33714 11-Aug-17 DroID_v2017_08 "Drer\trnau1apa, Drer\dazl, Drer\zgc:110796, Drer\hnrnpa1b, Drer\ncoa5, Drer\trnau1apb, Drer\srsf10a, Drer\eif4ba, Drer\wu:fq32h04, Drer\hnrnpc, Drer\hnrnpd, Drer\slirp, Drer\eif4h, Drer\zcrb1, Drer\hnrnpabb, Drer\zgc:55733, Drer\rbm34, Drer\cirbpa, Drer\hnrnpaba, Drer\hnrnpa3, Drer\raly" "Scer\CWC2, Scer\MUD1, Scer\NOP6, Scer\NOP15, Scer\MRN1, Scer\NAM8, Scer\NOP12, Scer\NAB6, Scer\NGR1" Cele\C50B8.1 "Xtro\hnrnpab, Xtro\ralyl, Xtro\hnrnpa1, Xtro\hnrnpd, Xtro\eif4h, Xtro\hnrnpa3, Xtro\hnrnpa2b1, Xtro\cirbp, Xtro\hnrnpc, Xtro\trnau1ap, Xtro\raly, Xtro\eif4b, Xtro\dazl, Xtro\hnrnpdl, Xtro\rbm34" "Mmus\Gm21379, Mmus\Eif4b, Mmus\Slirp, Mmus\Hnrnpc, Mmus\Msi2, Mmus\Rbm34, Mmus\Srsf12, Mmus\Srsf10, Mmus\Hnrnpd, Mmus\Cirbp, Mmus\Zcrb1, Mmus\Dazl, Mmus\Eif4h, Mmus\Hnrnpa1, Mmus\Trnau1ap, Mmus\Hnrnpa3, Mmus\Hnrnpa2b1, Mmus\Rbm31y, Mmus\Raly, Mmus\Boll, Mmus\Hnrnpab, Mmus\Tra2b" "Hsap\DAZ4, Hsap\RALY, Hsap\HNRNPA2B1, Hsap\HNRNPA1, Hsap\RBM3, Hsap\SRSF10, Hsap\DAZ3, Hsap\EIF4H, Hsap\DAZ2, Hsap\RBM34, Hsap\CIRBP, Hsap\HNRNPC, Hsap\HNRNPAB, Hsap\HNRNPA1L2, Hsap\HNRNPCL1, Hsap\TRNAU1AP, Hsap\BOLL, Hsap\RALYL, Hsap\HNRNPD, Hsap\SLIRP, Hsap\HNRNPA3, Hsap\EIF4B, Hsap\DAZL, Hsap\DAZ1" "feeding behavior defective,smell perception defective" FBgn0028112 l(3)S066317 lethal (3) S066317 http://flybase.org/reports/FBgn0028112 gene - - - "0663/17, l(3)S066317" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001764 l(1)M24 lethal (1) M24 http://flybase.org/reports/FBgn0001764 - gene - - - l(1)M24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026392 Or33a Odorant receptor 33a http://flybase.org/reports/FBgn0026392 - protein_coding_gene "transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from direct assay olfactory receptor activity ; GO:0004984 | non-traceable author statement inferred by curator from GO:0004888,GO:0007608" sensory perception of smell ; GO:0007608 | inferred from expression pattern sensory perception of smell ; GO:0007608 | inferred by curator from GO:0004984 sensory perception of smell ; GO:0007608 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | non-traceable author statement "33a, DOR73, CG16960, AN3, 33B.1, dor73, DOR33B.1, Or73, Or33B.1, Or33a" "IPR004117:Olfactory receptor, insect" CG16960 11-Aug-17 DroID_v2017_08 - - - - - - sensory neuron &&of antennal segment 3

"viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0044116 E(rst)C137 E(rst)C137 http://flybase.org/reports/FBgn0044116 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C137, E(rst)C137" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030996 CG14194 - http://flybase.org/reports/FBgn0030996 protein_coding_gene - - - CG14194 IPR019396:Transmembrane Fragile-X-F-associated protein CG14194 11-Aug-17 DroID_v2017_08 Drer\tmem185 - Cele\Y116A8C.9 "Xtro\tmem185a, Xtro\tmem60" "Mmus\Tmem185b, Mmus\Tmem185a, Mmus\Tmem60" "Hsap\TMEM60, Hsap\TMEM185A, Hsap\TMEM185B" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0040910 CG12685 - http://flybase.org/reports/FBgn0040910 protein_coding_gene - - - CG12685 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030161 CG15249 - http://flybase.org/reports/FBgn0030161 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15249 - CG15249 11-Aug-17 DroID_v2017_08 - Scer\HSP26 - - Mmus\Fadd Hsap\FADD FBgn0000489 Pka-C3 "Protein kinase, cAMP-dependent, catalytic subunit 3" http://flybase.org/reports/FBgn0000489 FBgn0004631 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9U969 cAMP-dependent protein kinase activity ; GO:0004691 | inferred from direct assay cAMP-dependent protein kinase activity ; GO:0004691 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay cAMP-dependent protein kinase complex ; GO:0005952 | inferred from sequence or structural similarity "PKA-C-3, CG6117, PKA, PKA C3, DC2, 5-23, Pk?5, Pk72A, Dpck, Pka-C3, PKA-C3, pka-C3" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG6117 11-Aug-17 DroID_v2017_08 "Drer\prkacbb, Drer\prkacaa, Drer\pak2b, Drer\LOC556339, Drer\prkx, Drer\prkg2, Drer\sgk2b, Drer\prkacab, Drer\prkacba, Drer\prkg1b" "Scer\TPK3, Scer\TPK2, Scer\YPK3, Scer\TPK1" "Cele\kin-1, Cele\F47F2.1" "Xtro\prkaca, Xtro\prkg2, Xtro\prkx, Xtro\prkacb" "Mmus\Prkacb, Mmus\Prkx, Mmus\Prkaca, Mmus\Prkg2, Mmus\Prkg1" "Hsap\PRKG2, Hsap\PRKG1, Hsap\PRKACA, Hsap\PRKX, Hsap\PRKACG, Hsap\PRKACB" " embryonic stage | stage 5 , pupal stage && adult stage , embryonic stage | cellular blastoderm , embryonic stage -- adult stage , embryonic stage | syncytial blastoderm " " organism | pair rule

, head mesoderm

,

ventral " "viable,fertile,visible,dominant" wing DRSC11254 IE 1.554634272 0.423352256 1.313304075 -4.195554011 0.417488872 0.606234897 FBgn0040528 CG15864 - http://flybase.org/reports/FBgn0040528 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG7553, CG15864" "IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG15864 11-Aug-17 DroID_v2017_08 "Drer\zgc:152670, Drer\p4ha2, Drer\p4ha1b, Drer\p4ha1a, Drer\p4ha3, Drer\p4htm, Drer\zgc:158254" - "Cele\phy-2, Cele\phy-4, Cele\C14E2.4, Cele\dpy-18, Cele\Y43F8B.19, Cele\phy-3" "Xtro\p4ha3, Xtro\p4ha2, Xtro\p4ha1" "Mmus\P4htm, Mmus\P4ha3, Mmus\P4ha1, Mmus\P4ha2" "Hsap\P4HA1, Hsap\P4HA3, Hsap\P4HA2, Hsap\P4HTM" FBgn0011070 l(1)Q23 lethal (1) Q23 http://flybase.org/reports/FBgn0011070 FBgn0010210 gene - - - l(1)Q23 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265071 CR44182 - http://flybase.org/reports/FBgn0265071 non_protein_coding_gene - - - CR44182 - CR44182 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042627 FASN2 Fatty acid synthase 2 http://flybase.org/reports/FBgn0042627 protein_coding_gene "oleoyl-[acyl-carrier-protein] hydrolase activity ; GO:0004320 | inferred from electronic annotation with InterPro:IPR023102 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity ; GO:0004316 | inferred from electronic annotation with InterPro:IPR023102 palmitoyl-[acyl-carrier-protein] hydrolase activity ; GO:0016296 | inferred from electronic annotation with InterPro:IPR023102 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity ; GO:0004319 | inferred from electronic annotation with InterPro:IPR023102 myristoyl-[acyl-carrier-protein] hydrolase activity ; GO:0016295 | inferred from electronic annotation with InterPro:IPR023102 [acyl-carrier-protein] S-malonyltransferase activity ; GO:0004314 | inferred from electronic annotation with InterPro:IPR023102 [acyl-carrier-protein] S-acetyltransferase activity ; GO:0004313 | inferred from electronic annotation with InterPro:IPR023102 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity ; GO:0004317 | inferred from electronic annotation with InterPro:IPR023102 3-oxoacyl-[acyl-carrier-protein] synthase activity ; GO:0004315 | inferred from electronic annotation with InterPro:IPR023102 phosphopantetheine binding ; GO:0031177 | inferred from electronic annotation with InterPro:IPR020806 fatty acid synthase activity ; GO:0004312 | inferred from mutant phenotype" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR013149 methyl-branched fatty acid biosynthetic process ; GO:1902321 | inferred from mutant phenotype cellular response to sucrose stimulus ; GO:0071329 | inferred from direct assay cuticle hydrocarbon biosynthetic process ; GO:0006723 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay "DM_7295849, CG3524, FASN[CG3524], FAS, mFAS, FAS[CG3524], v(2)k05816, FASN2, FAS-mb" "IPR018201:Beta-ketoacyl synthase, active site, IPR001031:Thioesterase, IPR009081:Phosphopantetheine binding ACP domain, IPR011032:GroES-like, IPR013149:Alcohol dehydrogenase, C-terminal, IPR014030:Beta-ketoacyl synthase, N-terminal, IPR014031:Beta-ketoacyl synthase, C-terminal, IPR014043:Acyl transferase, IPR016040:NAD(P)-binding domain, IPR016035:Acyl transferase/acyl hydrolase/lysophospholipase, IPR016036:Malonyl-CoA ACP transacylase, ACP-binding, IPR016039:Thiolase-like, IPR032821:Ketoacyl-synthetase, C-terminal extension, IPR020807:Polyketide synthase, dehydratase domain, IPR023102:Fatty acid synthase, domain 2, IPR020843:Polyketide synthase, enoylreductase domain, IPR029058:Alpha/Beta hydrolase fold, IPR013968:Polyketide synthase, ketoreductase domain, IPR020806:Polyketide synthase, phosphopantetheine-binding domain, IPR020841:Polyketide synthase, beta-ketoacyl synthase domain, IPR020801:Polyketide synthase, acyl transferase domain" CG3524 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-61p9.11, Drer\si:dkey-11k2.7, Drer\fasn" "Scer\CEM1, Scer\YML131W" "Cele\M106.3, Cele\fasn-1, Cele\C41A3.1, Cele\F32H2.6" "Xtro\ltb4dh, Xtro\fasn" "Mmus\Ptgr1, Mmus\Ptgr2, Mmus\Fasn" "Hsap\FASN, Hsap\PTGR1" "visible,lethal - all die before end of pupal stage,viable" "wing,leg" FBgn0026233 hab habanero http://flybase.org/reports/FBgn0026233 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available hab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024491 Bin1 Bicoid interacting protein 1 http://flybase.org/reports/FBgn0024491 "FBgn0038406, FBgn0047185" protein_coding_gene transcription corepressor activity ; GO:0003714 | inferred from genetic interaction with Kr protein binding ; GO:0005515 | inferred from physical interaction with bcd transcription factor binding ; GO:0008134 | inferred from physical interaction with Kr "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with Kr chromatin silencing ; GO:0006342 | inferred from genetic interaction with Kr mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" Sin3 complex ; GO:0016580 | inferred from sequence or structural similarity with EMBL:U96915 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "150001_at, SAP18, sap18, dSAP18, dSap18, bin1/dSAP18, bin1, CG6046, BcDNA:RE02417, Bin1, dsap18, Bin 1" "IPR010516:Sin3 associated polypeptide p18, IPR017250:Histone deacetylase complex, SAP18 subunit" CG6046 11-Aug-17 DroID_v2017_08 Drer\sap18 - Cele\C16C10.4 Xtro\sap18 "Mmus\Sap18b, Mmus\Sap18" Hsap\SAP18 "visible,homeotic,enhancer of variegation,lethal,recessive,heat sensitive,viable,maternal effect" "abdominal sternite bristle,ectopic,adult abdominal segment 6,adult abdominal segment 5,embryonic/first instar larval cuticle,anterior,germline clone,cephalopharyngeal skeleton" FBgn0031853 TTLL3B Tubulin tyrosine ligase-like 3B http://flybase.org/reports/FBgn0031853 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR013815 protein-glycine ligase activity ; GO:0070735 | inferred from direct assay protein-glycine ligase activity, initiating ; GO:0070736 | inferred from direct assay protein-glycine ligase activity, elongating ; GO:0070737 | inferred from direct assay" protein polyglycylation ; GO:0018094 | inferred from direct assay inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype axoneme assembly ; GO:0035082 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay axoneme ; GO:0005930 | inferred from direct assay microtubule cytoskeleton ; GO:0015630 | inferred from direct assay "TTLL3B, dmTTLL3B, CG11201" "IPR013815:ATP-grasp fold, subdomain 1, IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase" CG11201 11-Aug-17 DroID_v2017_08 "Drer\ttll3, Drer\ttll5, Drer\ttll10, Drer\ttll9, Drer\ttll1, Drer\ttl, Drer\ttll2" Scer\PBY1 "Cele\ttll-9, Cele\ttll-5" "Xtro\ttll1, Xtro\ttll3, Xtro\ttl, Xtro\LOC100158544, Xtro\ttll5, Xtro\ttll2" "Mmus\Ttll2, Mmus\Ttll5, Mmus\Ttl, Mmus\Ttll1, Mmus\Ttll9, Mmus\Ttll8, Mmus\Ttll10, Mmus\Ttll3" "Hsap\TTLL2, Hsap\TTLL10, Hsap\TTL, Hsap\TTLL5, Hsap\ARPC4, Hsap\ARPC4-TTLL3, Hsap\TTLL8, Hsap\TTLL9, Hsap\TTLL3, Hsap\TTLL1" "viable,male fertile,female fertile,partially lethal - majority die,male sterile,lethal,lethal - all die before end of pupal stage,some die during pupal stage" spermatid axoneme DRSC02133 IE 0.306881315 2.168655715 2.306026001 -0.025771814 0.213225408 0.714066771 FBgn0084463 Brkd Breakdance http://flybase.org/reports/FBgn0084463 gene - - - Brkd - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,dominant,heat sensitive,neurophysiology defective,recessive" "indirect flight muscle,heat sensitive" FBgn0037516 CG11286 - http://flybase.org/reports/FBgn0037516 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG11286 IPR032004:Protein of unknown function DUF4790 CG11286 11-Aug-17 DroID_v2017_08 - "Scer\NGG1, Scer\OAF3" Cele\nhr-111 - Mmus\Laptm5 Hsap\LAPTM5 "viable,visible" "chaeta,supernumerary,trichogen cell,tormogen cell,wing" FBgn0002040 l(2)37Dd lethal (2) 37Dd http://flybase.org/reports/FBgn0002040 FBgn0002042 gene - - - "l(2)OE36, l(2)OD8, l(2)37Df, l(2)37Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0083155 S(smoDN)1657 Suppressor of smoDN 1657 http://flybase.org/reports/FBgn0083155 gene - - - S(smoDN)1657 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032652 CG6870 - http://flybase.org/reports/FBgn0032652 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 - - CG6870 "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR018506:Cytochrome b5, heme-binding site" CG6870 11-Aug-17 DroID_v2017_08 "Drer\cyb5b, Drer\cyb5a" "Scer\OLE1, Scer\SCS7, Scer\CYB2, Scer\CYB5" "Cele\fat-3, Cele\cytb-5.2, Cele\C25A1.5, Cele\cytb-5.1, Cele\D2023.1" "Xtro\cyb5b, Xtro\cyb5a" "Mmus\Cyb5b, Mmus\Cyb5a, Mmus\Cyb5d1, Mmus\Fa2h, Mmus\Fads3" "Hsap\CYB5B, Hsap\CYB5A, Hsap\FADS1, Hsap\FA2H" FBgn0036497 Ran-like Ran-like http://flybase.org/reports/FBgn0036497 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W1A4 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000005711 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 GTP binding ; GO:0005525 | inferred from direct assay signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002041 protein export from nucleus ; GO:0006611 | inferred from sequence or structural similarity with HGNC:9846 ribosomal subunit export from nucleus ; GO:0000054 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 cytoplasm ; GO:0005737 | inferred from direct assay "CG7815, BcDNA:GH25818, anon-WO0140519.150, Ran-like, ran-like" "IPR002041:Ran GTPase, IPR005225:Small GTP-binding protein domain, IPR001806:Small GTPase superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7815 11-Aug-17 DroID_v2017_08 "Drer\rabl2, Drer\ran" "Scer\GSP1, Scer\GSP2" "Cele\ran-1, Cele\F11A5.4" "Xtro\rabl2b, Xtro\ran" "Mmus\Ran, Mmus\Rasl2-9, Mmus\1700009N14Rik, Mmus\Rabl2" "Hsap\RABL2B, Hsap\RAN, Hsap\RABL2A" viable FBgn0259260 EP-1052 - http://flybase.org/reports/FBgn0259260 gene - - - EP-1052 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0266379 CR45021 - http://flybase.org/reports/FBgn0266379 non_protein_coding_gene - - - CR45021 - CR45021 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039107 CG10300 - http://flybase.org/reports/FBgn0039107 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 CG10300 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG10300 11-Aug-17 DroID_v2017_08 "Drer\rlbp1a, Drer\sec14l7, Drer\rlbp1b, Drer\sec14l8, Drer\clvs2, Drer\ttpa, Drer\ttpal" "Scer\YKL091C, Scer\SFH5, Scer\SEC14" - "Xtro\mospd2, Xtro\sec14l3, Xtro\clvs2, Xtro\ttpal, Xtro\rlbp1, Xtro\clvs1, Xtro\ttpa, Xtro\sec14l1, Xtro\sec14l5" "Mmus\Sec14l5, Mmus\Ttpal, Mmus\Rlbp1, Mmus\Ttpa, Mmus\Sec14l3, Mmus\Sec14l4, Mmus\Sec14l2, Mmus\Clvs1, Mmus\Sec14l1, Mmus\Clvs2" "Hsap\SEC14L6, Hsap\TTPAL, Hsap\SEC14L5, Hsap\CLVS1, Hsap\TTPA, Hsap\SEC14L3, Hsap\SEC14L4, Hsap\SEC14L1, Hsap\SEC14L2, Hsap\CLVS2, Hsap\RLBP1" viable FBgn0259234 Camta Calmodulin-binding transcription activator http://flybase.org/reports/FBgn0259234 protein_coding_gene "DNA binding ; GO:0003677 | inferred from sequence or structural similarity calmodulin binding ; GO:0005516 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Camta sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000596526 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity" "response to light stimulus ; GO:0009416 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from direct assay "CG42332, camta, DmCAMTA, CG8809, Camta, dCAMTA, CG13952, CG13953" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site, IPR005559:CG-1 DNA-binding domain, IPR014756:Immunoglobulin E-set, IPR020683:Ankyrin repeat-containing domain, IPR013783:Immunoglobulin-like fold, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical, IPR002909:IPT domain" CG42332 11-Aug-17 DroID_v2017_08 "Drer\camta1a, Drer\camta1, Drer\camta1b, Drer\camta2" - Cele\camt-1 "Xtro\camta2, Xtro\camta1" "Mmus\Camta1, Mmus\Camta2" "Hsap\CAMTA2, Hsap\CAMTA1" FBgn0052631 CG32631 - http://flybase.org/reports/FBgn0052631 protein_coding_gene - - - "CG1733, CG32631" - CG32631 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013772 Cyp6a8 Cytochrome P450-6a8 http://flybase.org/reports/FBgn0013772 - protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR002402 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR002402 alkane 1-monooxygenase activity ; GO:0018685 | inferred from direct assay electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with Cyp6a2" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR002402, InterPro:IPR017972 response to caffeine ; GO:0031000 | inferred from direct assay lauric acid metabolic process ; GO:0048252 | inferred from direct assay insecticide metabolic process ; GO:0017143 | inferred from direct assay" endomembrane system ; GO:0012505 | inferred from direct assay "CG10248, 6a8, CYP6A8, P450, P-450, Cyt-P450-rAF5, Cyp6a8, CYP6a8" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site, IPR002402:Cytochrome P450, E-class, group II" CG10248 11-Aug-17 DroID_v2017_08 "Drer\cyp4t8, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp3a65, Drer\tbxas1, Drer\cyp4v8, Drer\cyp3c4, Drer\cyp3c2, Drer\cyp4f3, Drer\cyp4v7" Scer\ERG11 "Cele\cyp-25A1, Cele\cyp-13A5, Cele\cyp-13A4, Cele\cyp-25A4, Cele\cyp-13A3, Cele\cyp-33C4, Cele\cyp-25A3, Cele\cyp-32B1, Cele\cyp-13A12, Cele\cyp-44A1, Cele\cyp-13B2, Cele\cyp-13A11, Cele\cyp-32A1, Cele\cyp-31A2, Cele\cyp-43A1, Cele\cyp-13B1, Cele\cyp-29A2, Cele\cyp-13A1, Cele\cyp-31A3, Cele\cyp-13A10, Cele\cyp-37B1, Cele\cyp-29A3, Cele\cyp-42A1, Cele\cyp-13A8, Cele\cyp-13A2, Cele\cyp-25A6, Cele\cyp-13A7, Cele\cyp-13A6, Cele\cyp-25A2, Cele\cyp-29A4" "Xtro\tbxas1, Xtro\cyp3a5, Xtro\LOC100494419, Xtro\cyp3a4" "Mmus\Cyp4f37, Mmus\Cyp3a41b, Mmus\Cyp3a59, Mmus\Cyp4f15, Mmus\Cyp4a10, Mmus\Cyp3a41a, Mmus\Tbxas1, Mmus\Cyp4f39, Mmus\Cyp3a57, Mmus\Cyp4v3, Mmus\Cyp3a25, Mmus\Cyp3a11, Mmus\Cyp3a16, Mmus\Cyp8b1, Mmus\Cyp4f14, Mmus\Cyp3a44, Mmus\Cyp4a31, Mmus\Cyp4a14, Mmus\Cyp4a12a, Mmus\Cyp4f16, Mmus\Cyp4f13, Mmus\Cyp3a13, Mmus\Cyp4f18, Mmus\Cyp4a32, Mmus\Cyp4a12b, Mmus\Cyp4b1" "Hsap\CYP4F2, Hsap\CYP4X1, Hsap\CYP4B1, Hsap\CYP3A4, Hsap\CYP4A11, Hsap\CYP4F11, Hsap\CYP3A43, Hsap\CYP4F22, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4F3, Hsap\CYP4A22, Hsap\CYP8B1, Hsap\CYP4F12, Hsap\CYP3A7, Hsap\CYP4Z1, Hsap\CYP3A5, Hsap\CYP4V2, Hsap\CYP4F8, Hsap\TBXAS1" adult stage viable FBgn0061126 l(3)S003405b lethal (3) S003405b http://flybase.org/reports/FBgn0061126 gene - - - "0034/05, l(3)S003405b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027167 l(2)IH2 lethal (2) IH2 http://flybase.org/reports/FBgn0027167 - gene - - - l(2)IH2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065087 snmRNA:649 small non-messenger RNA 649 http://flybase.org/reports/FBgn0065087 non_protein_coding_gene - - - "Dm-649, CR33685, snmRNA:649" - CR33685 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004439 prd2 paired-like 2 http://flybase.org/reports/FBgn0004439 - gene - - - prd2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053494 CG33494 - http://flybase.org/reports/FBgn0053494 protein_coding_gene - - - "BcDNA:LP10657, CG33494" - CG33494 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC13715 I 1.720135242 -1.469636193 0.046769554 -1.213704151 0.108345919 -0.538793309 FBgn0267104 CG45544 - http://flybase.org/reports/FBgn0267104 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lincRNA.886, CG45544" - CG45544 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033471 CG12134 - http://flybase.org/reports/FBgn0033471 protein_coding_gene - - - CG12134 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat" CG12134 11-Aug-17 DroID_v2017_08 Drer\wdr89 "Scer\HAT2, Scer\YNL035C" "Cele\Y54H5A.1, Cele\T18D3.1, Cele\wdr-23" Xtro\wdr89 Mmus\Wdr89 Hsap\WDR89 "viable,fertile" FBgn0283433 CG46276 - http://flybase.org/reports/FBgn0283433 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 "CG46276, SdicB" "IPR001680:WD40 repeat, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG46276 11-Aug-17 DroID_v2017_08 "Drer\dync1i2b, Drer\LOC103908626, Drer\dync1i1" Scer\PFS2 "Cele\prp-17, Cele\dyci-1" "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Dync1i1, Mmus\Dync1i2" "Hsap\DYNC1I2, Hsap\DYNC1I1" FBgn0033740 dgt5 dim gamma-tubulin 5 http://flybase.org/reports/FBgn0033740 protein_coding_gene - mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay HAUS complex ; GO:0070652 | colocalizes_with inferred from direct assay spindle ; GO:0005819 | colocalizes_with inferred from direct assay "Dgt5, dgt5, CG8828, msd2" - CG8828 11-Aug-17 DroID_v2017_08 - Scer\USO1 - - - - viable FBgn0036343 CG14115 - http://flybase.org/reports/FBgn0036343 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14115 IPR006631:Protein of unknown function DM4/12 CG14115 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030300 Sk1 Sphingosine kinase 1 http://flybase.org/reports/FBgn0030300 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 diacylglycerol kinase activity ; GO:0004143 | non-traceable author statement D-erythro-sphingosine kinase activity ; GO:0017050 | inferred from direct assay sphingolipid metabolic process ; GO:0006665 | inferred from direct assay phosphorylation ; GO:0016310 | inferred from direct assay phosphorylation ; GO:0016310 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG1747, Sphk1, SK1, Sk1" "IPR001206:Diacylglycerol kinase, catalytic domain, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG1747 11-Aug-17 DroID_v2017_08 "Drer\sphk2, Drer\sphk1, Drer\zgc:158263, Drer\cerk" "Scer\TIM54, Scer\LCB5, Scer\LCB4" "Cele\T10B11.2, Cele\sphk-1" "Xtro\cerkl, Xtro\sphk2, Xtro\sphk1" "Mmus\Sphk1, Mmus\Cerk, Mmus\Sphk2" "Hsap\SPHK2, Hsap\CERKL, Hsap\SPHK1, Hsap\CERK" "viable,fertile" rhabdomereGMR.PF FBgn0065172 l(3)SH020 lethal (3) SH020 http://flybase.org/reports/FBgn0065172 gene - - - "l(3)SH020, l(2)SH3 020" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266229 CR44924 - http://flybase.org/reports/FBgn0266229 non_protein_coding_gene - - - "CR44924, lincRNA.681" - CR44924 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067776 fkl fraenkel http://flybase.org/reports/FBgn0067776 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fkl - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038163 CG10841 - http://flybase.org/reports/FBgn0038163 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "anon-WO0140519.42, CG10841" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG10841 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0014381 rip ripcord http://flybase.org/reports/FBgn0014381 FBgn0015503 gene - - - "VIII, l(3)65Da, rip" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005758 l(1)TK402 lethal (1) TK402 http://flybase.org/reports/FBgn0005758 - gene - - - "l402, l(1)TK402" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" eye FBgn0052452 CG32452 - http://flybase.org/reports/FBgn0052452 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD04526, CG32452" - CG32452 11-Aug-17 DroID_v2017_08 - - - - - - DRSC11581 I -1.700754986 0.827866467 0.840033113 -0.38521593 -0.111060082 0.937626534 FBgn0013387 anon-100CDb anon-100CDb http://flybase.org/reports/FBgn0013387 - gene - - - anon-100CDb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037700 CG8149 - http://flybase.org/reports/FBgn0037700 protein_coding_gene - "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern" - CG8149 IPR003034:SAP domain CG8149 11-Aug-17 DroID_v2017_08 Drer\sarnp Scer\THO1 "Cele\Y53G8AR.6, Cele\C39E9.12, Cele\acin-1" Xtro\sarnp Mmus\Sarnp Hsap\SARNP "viable,visible" trichogen cell FBgn0025572 RNA-guanine-7-methyltransferase RNA (guanine-7-)methyltransferase http://flybase.org/reports/FBgn0025572 - gene tRNA (guanine-N7-)-methyltransferase activity ; GO:0008176 | inferred from sequence or structural similarity - - RNA-guanine-7-methyltransferase - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004751 l(3)89Bd lethal (3) 89Bd http://flybase.org/reports/FBgn0004751 - gene - - - l(3)89Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052228 CG32228 - http://flybase.org/reports/FBgn0052228 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32228 - CG32228 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0084013 CG41449 - http://flybase.org/reports/FBgn0084013 protein_coding_gene - - - CG41449 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031913 CG5958 - http://flybase.org/reports/FBgn0031913 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 lipid particle ; GO:0005811 | inferred from direct assay CG5958 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG5958 11-Aug-17 DroID_v2017_08 "Drer\rlbp1b, Drer\sec14l7, Drer\clvs2, Drer\rlbp1a, Drer\ttpa, Drer\ttpal, Drer\sec14l8" "Scer\SFH5, Scer\YKL091C, Scer\SEC14" - "Xtro\mospd2, Xtro\rlbp1, Xtro\ttpal, Xtro\clvs1, Xtro\sec14l5, Xtro\sec14l1, Xtro\clvs2, Xtro\ttpa, Xtro\sec14l3" "Mmus\Sec14l4, Mmus\Rlbp1, Mmus\Clvs1, Mmus\Ttpa, Mmus\Sec14l3, Mmus\Ttpal, Mmus\Sec14l2, Mmus\Sec14l1, Mmus\Clvs2, Mmus\Sec14l5" "Hsap\SEC14L1, Hsap\SEC14L3, Hsap\TTPA, Hsap\SEC14L2, Hsap\SEC14L5, Hsap\RLBP1, Hsap\CLVS2, Hsap\TTPAL, Hsap\SEC14L4, Hsap\SEC14L6, Hsap\CLVS1" viable FBgn0036775 CG5147 - http://flybase.org/reports/FBgn0036775 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007811 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000334172 transcription from RNA polymerase III promoter ; GO:0006383 | inferred from electronic annotation with InterPro:IPR007811 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000334172 CG5147 IPR007811:DNA-directed RNA polymerase III subunit RPC4 CG5147 11-Aug-17 DroID_v2017_08 "Drer\zgc:171971, Drer\polr3d" Scer\RPC53 - Xtro\polr3d Mmus\Polr3d Hsap\POLR3D "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260050 2L4332 - http://flybase.org/reports/FBgn0260050 gene - - - 2L4332 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0036565 CG5235 - http://flybase.org/reports/FBgn0036565 protein_coding_gene copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN001605435 dopamine beta-monooxygenase activity ; GO:0004500 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000323, InterPro:IPR000945, InterPro:IPR014784, InterPro:IPR020611 norepinephrine biosynthetic process ; GO:0042421 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 dopamine catabolic process ; GO:0042420 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 octopamine biosynthetic process ; GO:0006589 | inferred from biological aspect of ancestor with PANTHER:PTN000806665" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 secretory granule membrane ; GO:0030667 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 CG5235 "IPR000323:Copper type II, ascorbate-dependent monooxygenase, N-terminal, IPR000945:Dopamine beta-hydroxylase-related, IPR005018:DOMON domain, IPR008977:PHM/PNGase F domain, IPR014784:Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, IPR024548:Copper type II ascorbate-dependent monooxygenase, C-terminal, IPR020611:Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site" CG5235 11-Aug-17 DroID_v2017_08 "Drer\dbh, Drer\moxd1l, Drer\moxd1, Drer\ints8" - "Cele\tbh-1, Cele\Y48G10A.4" "Xtro\moxd1, Xtro\dbh, Xtro\ints8" "Mmus\Moxd2, Mmus\Dbh, Mmus\Moxd1, Mmus\Ints8" "Hsap\DBH, Hsap\INTS8, Hsap\MOXD1" "viable,fertile" FBgn0086233 hN13 - http://flybase.org/reports/FBgn0086233 gene - - - hN13 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262211 mir-2498 mir-2498 stem loop http://flybase.org/reports/FBgn0262211 miRNA_gene - - - "mir-2498, CR42918, chou22, dme-mir-2498" - CR42918 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032814 CG10366 - http://flybase.org/reports/FBgn0032814 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG10366 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG10366 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-79k12.2, Drer\prdm10" - Cele\sdz-12 - "Mmus\Zfp953, Mmus\Prdm10" "Hsap\ZNF680, Hsap\PRDM10, Hsap\ZNF682" viable FBgn0005447 l(1)v219 lethal (1) v219 http://flybase.org/reports/FBgn0005447 - gene - - - "l(1)219, l(1)v219" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032371 CG4983 - http://flybase.org/reports/FBgn0032371 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.134, CG4983" - CG4983 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040240 bc2 buckled on 2 http://flybase.org/reports/FBgn0040240 gene - - - "bc, bc2" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0035293 CG5687 - http://flybase.org/reports/FBgn0035293 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "anon-EST:Posey42, CG5687, dSLC5A2" IPR001734:Sodium/solute symporter CG5687 11-Aug-17 DroID_v2017_08 "Drer\slc5a2, Drer\slc5a12, Drer\slc5a8, Drer\slc5a11, Drer\slc5a3a, Drer\slc5a1, Drer\slc5a9, Drer\slc5a6b, Drer\LOC568338, Drer\slc5a5, Drer\slc5a6a, Drer\si:dkeyp-9d4.5, Drer\slc5a8l" Scer\DUR3 "Cele\ZK822.5, Cele\F52H2.4" "Xtro\slc5a5, Xtro\slc5a11, Xtro\slc5a1.1, Xtro\slc5a2, Xtro\slc5a9, Xtro\slc5a12, Xtro\slc5a8" "Mmus\Slc5a6, Mmus\Gm5134, Mmus\Slc5a4a, Mmus\Slc5a2, Mmus\Slc5a4b, Mmus\Slc5a10, Mmus\Slc5a11, Mmus\Slc5a8, Mmus\Slc5a1, Mmus\Slc5a5, Mmus\Slc5a3, Mmus\Slc5a9, Mmus\Slc5a12" "Hsap\SLC5A6, Hsap\SLC5A5, Hsap\SLC5A8, Hsap\SLC5A3, Hsap\SLC5A10, Hsap\SLC5A12, Hsap\SLC5A2, Hsap\SLC5A1, Hsap\SLC5A4, Hsap\SLC5A9, Hsap\SLC5A11" viable FBgn0267716 CR46049 - http://flybase.org/reports/FBgn0267716 non_protein_coding_gene - - - "CR46049, Mgn1733" - CR46049 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022298 l(1)M123.2 lethal (1) M123.2 http://flybase.org/reports/FBgn0022298 - gene - - - "M123.2, l(1)M123.2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014278 l(2)k17039 lethal (2) k17039 http://flybase.org/reports/FBgn0014278 - gene - - - "l(2)170/39, l(2)k17039" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262878 CG43233 - http://flybase.org/reports/FBgn0262878 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43233 - CG43233 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262001 CG42819 - http://flybase.org/reports/FBgn0262001 protein_coding_gene - - - "CG42819, CG13394" - CG42819 11-Aug-17 DroID_v2017_08 - - - - - - DRSC02265 EK 0.561094474 0.668251357 4.116655123 0.374203322 -0.641144644 -1.887395999 FBgn0039040 CG13833 - http://flybase.org/reports/FBgn0039040 protein_coding_gene - - - CG13833 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG13833 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-221h15.4, Drer\sdr16c5b, Drer\dhrs3b, Drer\rdh20, Drer\rdh10a, Drer\sdr16c5a, Drer\dhrs3a" "Scer\TDA5, Scer\YDL114W" "Cele\dhs-18, Cele\dhs-29, Cele\dhs-4, Cele\dhs-6" "Xtro\sdr16c5, Xtro\rdh10, Xtro\hsd17b13, Xtro\hsd17b11, Xtro\dhrs3" "Mmus\Hsd17b13, Mmus\Sdr16c6, Mmus\Hsdl2, Mmus\Dhrs3, Mmus\Hsd17b11, Mmus\Sdr16c5, Mmus\Rdh10" "Hsap\DHRS3, Hsap\HSD17B13, Hsap\HSDL2, Hsap\RDH10, Hsap\HSD17B11, Hsap\SDR16C5" viable FBgn0050416 CG30416 - http://flybase.org/reports/FBgn0050416 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG9803, BcDNA:AT11052, CG30416" - CG30416 11-Aug-17 DroID_v2017_08 - - - Xtro\ccdc84 Mmus\Ccdc84 Hsap\CCDC84 viable FBgn0013994 Nc98F Neural conserved at 98F http://flybase.org/reports/FBgn0013994 - gene - - - "NC98F, Nc98F" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250893 zaa77f10 - http://flybase.org/reports/FBgn0250893 gene - - - "zaa77f10, zaa77f10y1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263996 CG43739 - http://flybase.org/reports/FBgn0263996 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43739, Dm_2L:110584" - CG43739 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267534 CR45874 - http://flybase.org/reports/FBgn0267534 non_protein_coding_gene - - - "CR45874, Mgn3857" - CR45874 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262062 SG13 - http://flybase.org/reports/FBgn0262062 gene - - - SG13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025162 l(2)49Fp lethal (2) 49Fp http://flybase.org/reports/FBgn0025162 - gene - - - "vr17, l(2)49Fp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,non-suppressor of variegation,dominant" FBgn0260026 CG42494 - http://flybase.org/reports/FBgn0260026 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG42494 IPR002557:Chitin binding domain CG42494 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040586 CG17624 - http://flybase.org/reports/FBgn0040586 protein_coding_gene - - - CG17624 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264529 l(3)ff5 - http://flybase.org/reports/FBgn0264529 gene - - - l(3)ff5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0016722 Reg-8 Rhythmically expressed gene 8 http://flybase.org/reports/FBgn0016722 - gene - - - "Dreg-8, Reg-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , embryonic stage | late " adult head

FBgn0265444 CR44344 - http://flybase.org/reports/FBgn0265444 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR44344 - CR44344 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040377 Vha36-3 Vacuolar H[+] ATPase 36kD subunit 3 http://flybase.org/reports/FBgn0040377 protein_coding_gene "ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from electronic annotation with InterPro:IPR002699 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033176" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033176 proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity with Vha36-1 "EG:BACR25B3.4, CG8310, Vha36-3, vha36-3" "IPR002699:ATPase, V1 complex, subunit D" CG8310 11-Aug-17 DroID_v2017_08 "Drer\atp6v1d, Drer\alkbh1" Scer\VMA8 Cele\vha-14 "Xtro\alkbh1, Xtro\atp6v1d" "Mmus\Alkbh1, Mmus\Atp6v1d" Hsap\ATP6V1D FBgn0001817 l(1)P2 lethal (1) P2 http://flybase.org/reports/FBgn0001817 - gene - - - l(1)P2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0043875 mod(mdg4)::Trl mod(mdg4)::Trl http://flybase.org/reports/FBgn0043875 engineered_fusion_gene - - - mod(mdg4)::Trl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034972 CG10339 - http://flybase.org/reports/FBgn0034972 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neurexin family protein binding ; GO:0042043 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synapse assembly ; GO:0007416 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 CG10339 "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG10339 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-93f2.1, Drer\nlgn2a, Drer\nlgn2b, Drer\cell, Drer\nlgn3a, Drer\nlgn4a, Drer\ces3, Drer\cel.1, Drer\nlgn3b, Drer\nlgn1, Drer\nlgn4b, Drer\ces2" - "Cele\ZK994.1, Cele\ZC376.1, Cele\ZC376.2, Cele\Y75B8A.3, Cele\nlg-1, Cele\ZC376.3, Cele\B0238.1, Cele\T02B5.1, Cele\W02B12.4, Cele\glit-1, Cele\T02B5.3" "Xtro\nlgn4x, Xtro\ces2, Xtro\ces3, Xtro\cel, Xtro\LOC100494782, Xtro\nlgn2, Xtro\nlgn3" "Mmus\Ces1b, Mmus\Ces3b, Mmus\Ces4a, Mmus\Ces2f, Mmus\Ces1h, Mmus\Ces2h, Mmus\Ces2c, Mmus\Ces2g, Mmus\Ces1e, Mmus\Nlgn1, Mmus\Ces1f, Mmus\Cel, Mmus\Ces1c, Mmus\Ces2e, Mmus\Ces2a, Mmus\Nlgn2, Mmus\Ces5a, Mmus\Ces1d, Mmus\Nlgn3, Mmus\Ces1g, Mmus\Ces3a, Mmus\Ces2b" "Hsap\NLGN1, Hsap\NLGN3, Hsap\CES1, Hsap\NLGN2, Hsap\CEL, Hsap\CES2, Hsap\CES3, Hsap\CES5A, Hsap\NLGN4Y, Hsap\CES4A, Hsap\NLGN4X" viable FBgn0035968 Slc45-1 Solute carrier family 45 member 1 http://flybase.org/reports/FBgn0035968 protein_coding_gene sucrose transmembrane transporter activity ; GO:0008515 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 sucrose transport ; GO:0015770 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 cytoplasmic vesicle ; GO:0031410 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "CG4484, scrt, Slc45-1" "IPR020846:Major facilitator superfamily domain, IPR011701:Major facilitator superfamily" CG4484 11-Aug-17 DroID_v2017_08 "Drer\LOC100329687, Drer\zgc:77158, Drer\slc45a1, Drer\slc45a3, Drer\slc45a2, Drer\slc45a4" - Cele\srab-2 "Xtro\slc45a1, Xtro\slc45a3, Xtro\slc45a4, Xtro\slc45a2" "Mmus\Slc45a4, Mmus\Slc45a3, Mmus\Slc45a2, Mmus\Slc45a1" "Hsap\SLC45A1, Hsap\SLC45A2, Hsap\SLC45A4, Hsap\SLC45A3" "partially lethal - majority die,viable" FBgn0033636 tou toutatis http://flybase.org/reports/FBgn0033636 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001739, InterPro:IPR016177 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876, InterPro:IPR001965 transcription factor binding ; GO:0008134 | inferred from physical interaction with pnr protein binding ; GO:0005515 | inferred from physical interaction with Iswi inferred from physical interaction with Chi" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype ATP-dependent chromatin remodeling ; GO:0043044 | inferred from direct assay nervous system development ; GO:0007399 | inferred from mutant phenotype polytene chromosome ; GO:0005700 | colocalizes_with inferred from direct assay ISWI-type complex ; GO:0031010 | inferred from direct assay "Dm Tou, CG10897, gene VI, VI, EP(2)0622, EP622, anon-48Ad, EP0622, tou, TIP5, Tou, TOU" "IPR018359:Bromodomain, conserved site, IPR018501:DDT domain, IPR001487:Bromodomain, IPR001739:Methyl-CpG DNA binding, IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR016177:DNA-binding domain, IPR019787:Zinc finger, PHD-finger, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR028942:WHIM1 domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR028941:WHIM2 domain" CG10897 11-Aug-17 DroID_v2017_08 "Drer\baz2a, Drer\baz1b, Drer\baz1a, Drer\LOC100536981, Drer\baz2ba, Drer\sp100.3, Drer\sp100.1" "Scer\GCN5, Scer\SPT7, Scer\YPL216W" "Cele\baz-2, Cele\nurf-1" "Xtro\baz1b, Xtro\baz2a, Xtro\baz2b, Xtro\baz1a" "Mmus\Baz2b, Mmus\Baz2a, Mmus\Baz1a, Mmus\Baz1b" "Hsap\BAZ2B, Hsap\BAZ2A, Hsap\BAZ1A, Hsap\BAZ1B" "viable,fertile,visible,poor,recessive,lethal" "wing,scutellar bristle,ectopic,dorsocentral bristle,supernumerary,wing vein L5,trichogen cell" FBgn0013937 E(sina)1 Enhancer of seven in absentia 1 http://flybase.org/reports/FBgn0013937 - gene - - - E(sina)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" photoreceptor cell R7 FBgn0043586 EP595b EP595b http://flybase.org/reports/FBgn0043586 gene - - - "EP(3)0595b, EP0595b, EP595b" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013226 E(var)113 E(var)113 http://flybase.org/reports/FBgn0013226 - gene - - - E(var)113 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0033233 Kdm4A Lysine (K)-specific demethylase 4A http://flybase.org/reports/FBgn0033233 protein_coding_gene histone demethylase activity (H3-K36 specific) ; GO:0051864 | inferred from sequence or structural similarity with UniProtKB:O75164 histone demethylase activity (H3-K9 specific) ; GO:0032454 | inferred from mutant phenotype histone demethylase activity (H3-K36 specific) ; GO:0051864 | inferred from mutant phenotype histone demethylase activity (H3-K36 specific) ; GO:0051864 | inferred from direct assay "histone H3-K36 demethylation ; GO:0070544 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:O75164 histone demethylation ; GO:0016577 | inferred from sequence or structural similarity with UniProtKB:O75164 histone H3-K9 demethylation ; GO:0033169 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:O75164 heterochromatin ; GO:0000792 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "KDM4A, CG15835, Kdm4A, dKDM4A, dJMJD2(1), dkdm4a" "IPR003347:JmjC domain, IPR003349:JmjN domain" CG15835 11-Aug-17 DroID_v2017_08 "Drer\kdm4aa, Drer\kdm4ab, Drer\kdm4c, Drer\kdm4b" "Scer\RPH1, Scer\GIS1" Cele\jmjd-2 "Xtro\kdm4a, Xtro\kdm4b, Xtro\kdm4c" "Mmus\Kdm4b, Mmus\Kdm4d, Mmus\Kdm4a, Mmus\Kdm4c" "Hsap\KDM4D, Hsap\KDM4C, Hsap\KDM4A, Hsap\KDM4B, Hsap\KDM4E" "viable,short lived,male limited,recessive,fertile,partially lethal,male" wing FBgn0003214 RD(1) Recovery disrupter of 1 http://flybase.org/reports/FBgn0003214 - gene - - - "RD, RD(1)" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,reduced" FBgn0002860 Mst66D Male-specific RNA 66D http://flybase.org/reports/FBgn0002860 - gene - - - "mst349, Mst66D" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003016 osp outspread http://flybase.org/reports/FBgn0003016 "FBgn0004947, FBgn0010673, FBgn0027874, FBgn0065995" protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3479, v(2)rJ571, BG:DS07721.2, BG:DS01486.7, BG:DS01486.5, l(2)rJ571, anon-WO02059370.75, alw, osp" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG3479 11-Aug-17 DroID_v2017_08 "Drer\mprip, Drer\triobpb, Drer\si:ch73-103b11.2, Drer\triobpa" - Cele\F10G8.8 "Xtro\triobp, Xtro\mprip" "Mmus\Mprip, Mmus\Triobp" "Hsap\TRIOBP, Hsap\MPRIP" "visible,recessive,partially lethal - majority die,lethal,viable,fertile,eye color defective" "crystal cell,wing,thorax" FBgn0041578 BC1 BC1 http://flybase.org/reports/FBgn0041578 gene - - - BC1 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived adult FBgn0013564 l(3)ry78 lethal (3) ry78 http://flybase.org/reports/FBgn0013564 - gene - - - "l(3)78, l(3)ry78" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044070 E(rst)K166 E(rst)K166 http://flybase.org/reports/FBgn0044070 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "K166, E(rst)K166" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0051010 CG31010 - http://flybase.org/reports/FBgn0051010 protein_coding_gene - - - "NEST:bs21b05, BcDNA:AT12704, CG31010" - CG31010 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028530 mTTF mitochondrial transcription termination factor http://flybase.org/reports/FBgn0028530 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from electronic annotation with InterPro:IPR003690 DNA binding ; GO:0003677 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003690 termination of mitochondrial transcription ; GO:0006393 | inferred from direct assay" mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN001035337 mitochondrion ; GO:0005739 | inferred from direct assay "DmTTF, CG18124, DS01068.4, BG:DS01068.4, mTTF" "IPR003690:Transcription termination factor, mitochondrial/chloroplastic" CG18124 11-Aug-17 DroID_v2017_08 "Drer\mterf3, Drer\mterf1, Drer\mterf2" - Cele\C50F4.12 - "Mmus\Mterf1b, Mmus\Mterf2, Mmus\Mterf3, Mmus\Mterf1a" "Hsap\MTERF2, Hsap\MTERF3, Hsap\MTERF1" viable FBgn0046333 fs(2)38ABa fs(2)38ABa http://flybase.org/reports/FBgn0046333 gene - - - "fs in 38A/B, fs(2)38ABa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026741 mRpL18 mitochondrial ribosomal protein L18 http://flybase.org/reports/FBgn0026741 - protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9H0U6 5S rRNA binding ; GO:0008097 | inferred from biological aspect of ancestor with PANTHER:PTN000307352 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR005484 mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9H0U6 "MRP-L18, HL, anon-49Ca, CG12373, mRpL18" IPR005484:Ribosomal protein L18 CG12373 11-Aug-17 DroID_v2017_08 Drer\mrpl18 - Cele\mrpl-18 Xtro\mrpl18 Mmus\Mrpl18 Hsap\MRPL18 "viable,visible" trichogen cell FBgn0266397 CR45037 - http://flybase.org/reports/FBgn0266397 non_protein_coding_gene - - - CR45037 - CR45037 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259632 B0377 - http://flybase.org/reports/FBgn0259632 gene - - - B0377 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta,ectopic" FBgn0054057 CG34057 - http://flybase.org/reports/FBgn0054057 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 cellular_component ; GO:0005575 | no biological data available "CG13904, CG34057, dC1GalT6" IPR003378:Fringe-like CG34057 11-Aug-17 DroID_v2017_08 "Drer\LOC564281, Drer\si:dkey-202e17.1, Drer\c1galt1c1, Drer\c1galt1a, Drer\c1galt1b" - "Cele\C17A2.3, Cele\C02H6.1, Cele\F56H6.1, Cele\F37A4.3, Cele\E03H4.3, Cele\bus-4, Cele\W09D10.5, Cele\C38H2.2, Cele\C16D9.6, Cele\Y38C1AB.5, Cele\Y38C1AB.1, Cele\T09E11.12" "Xtro\c1galt1, Xtro\LOC100496837" "Mmus\C1galt1, Mmus\C1galt1c1" "Hsap\C1GALT1C1, Hsap\C1GALT1" FBgn0036780 CG7330 - http://flybase.org/reports/FBgn0036780 protein_coding_gene - - - "BcDNA:RE22290, CG7330" - CG7330 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037208 CG8741 - http://flybase.org/reports/FBgn0037208 protein_coding_gene - - - CG8741 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038854 CG7044 - http://flybase.org/reports/FBgn0038854 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7044 "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG7044 11-Aug-17 DroID_v2017_08 Drer\brat1 - - Xtro\brat1 Mmus\Brat1 Hsap\BRAT1 viable FBgn0037717 CG8301 - http://flybase.org/reports/FBgn0037717 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG8301 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8301 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-33c14.6, Drer\si:ch211-241b2.4, Drer\gtf3ab, Drer\si:ch211-119o8.6, Drer\zgc:113220" Scer\PZF1 "Cele\zfp-2, Cele\Y55F3AM.14" Xtro\LOC100489238 "Mmus\Zfp189, Mmus\Zfp873, Mmus\Zfp810, Mmus\Zbtb41" "Hsap\ZNF560, Hsap\ZBTB41, Hsap\ZNF782" "viable,fertile" FBgn0061148 l(3)S000101b lethal (3) S000101b http://flybase.org/reports/FBgn0061148 gene - - - "0001/01, l(3)S000101b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032965 CG11629 - http://flybase.org/reports/FBgn0032965 protein_coding_gene - - - CG11629 IPR031958:Protein of unknown function DUF4778 CG11629 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002090 l(2)56a lethal (2) 56a http://flybase.org/reports/FBgn0002090 - gene - - - l(2)56a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034965 ppk29 pickpocket 29 http://flybase.org/reports/FBgn0034965 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 RNA interference ; GO:0016246 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG13568, ppk29, nope" IPR001873:Epithelial sodium channel CG13568 11-Aug-17 DroID_v2017_08 "Drer\asic2, Drer\asic1a, Drer\asic1c, Drer\asic1b, Drer\asic4b, Drer\asic4a" - "Cele\delm-2, Cele\acd-5, Cele\acd-2, Cele\acd-3, Cele\acd-4, Cele\flr-1, Cele\delm-1, Cele\del-7, Cele\acd-1" "Xtro\scnn1g, Xtro\scnn1d, Xtro\asic4, Xtro\asic5, Xtro\scnn1a, Xtro\scnn1b, Xtro\asic1" "Mmus\Scnn1g, Mmus\Scnn1b, Mmus\Asic4, Mmus\Asic2, Mmus\Scnn1a, Mmus\Asic5, Mmus\Asic1, Mmus\Asic3" "Hsap\SCNN1B, Hsap\SCNN1G, Hsap\ASIC4, Hsap\ASIC2, Hsap\ASIC3, Hsap\SCNN1A, Hsap\ASIC1, Hsap\ASIC5, Hsap\SCNN1D" "behavior defective,courtship behavior defective,paralytic,heat sensitive,viable,fertile,neurophysiology defective,locomotor behavior defective,male,recessive" "motor neuron,heat sensitive" FBgn0041759 eth-aS307 eth-aS307 http://flybase.org/reports/FBgn0041759 gene - - - "eth[aS]307, eth-aS307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0060950 l(3)S036916c lethal (3) S036916c http://flybase.org/reports/FBgn0060950 gene - - - "0369/16, l(3)S036916c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal" FBgn0264337 CR43793 - http://flybase.org/reports/FBgn0264337 non_protein_coding_gene - - - CR43793 - CR43793 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029974 dpr14 defective proboscis extension response 14 http://flybase.org/reports/FBgn0029974 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG10946, Dpr-14, CT30653, dpr14, Dpr14" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003598:Immunoglobulin subtype 2" CG10946 11-Aug-17 DroID_v2017_08 "Drer\LOC101885725, Drer\LOC101885444, Drer\si:dkey-65b12.12, Drer\si:ch211-163c2.2, Drer\LOC100333196" - Cele\zig-8 "Xtro\obsl1, Xtro\nfasc" Mmus\Amica1 "Hsap\CADM4, Hsap\CADM3, Hsap\CADM1, Hsap\CADM2" viable FBgn0053697 CG33697 - http://flybase.org/reports/FBgn0053697 protein_coding_gene - - - "BG:DS08249.5, DS08249.5, CG33697" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028097 l(3)S074103 lethal (3) S074103 http://flybase.org/reports/FBgn0028097 gene - - - "0741/03, l(3)S074103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024561 l(3)L5541 lethal (3) L5541 http://flybase.org/reports/FBgn0024561 - gene - - - l(3)L5541 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" crystal cell FBgn0043893 l(1)C31 lethal (1) C31 http://flybase.org/reports/FBgn0043893 gene - - - l(1)C31 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic head,salivary gland" FBgn0261041 stj straightjacket http://flybase.org/reports/FBgn0261041 protein_coding_gene voltage-gated calcium channel activity ; GO:0005245 | inferred from sequence or structural similarity with UniProtKB:Q8CFG5 synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from direct assay negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity with UniProtKB:Q8CFG5 presynaptic active zone ; GO:0048786 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay "dalpha[[2]]delta-3, stj, CG12295, alpha[[2]]delta, l(2)k10814, alpha[[2]]delta-3" "IPR002035:von Willebrand factor, type A, IPR013608:VWA N-terminal, IPR033479:Double Cache domain 1, IPR013680:Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region" CG12295 11-Aug-17 DroID_v2017_08 "Drer\cacna2d3, Drer\cacna2d3a, Drer\cacna2d4b, Drer\cacna2d4a, Drer\cacna2d2b, Drer\cacna2d2a, Drer\cacna2d1a, Drer\cachd1" - "Cele\unc-36, Cele\tag-180" "Xtro\cachd1, Xtro\cacna2d3, Xtro\cacna2d2, Xtro\cacna2d4, Xtro\cacna2d1" "Mmus\Cacna2d2, Mmus\Cacna2d4, Mmus\Cacna2d1, Mmus\Cacna2d3, Mmus\Cachd1" "Hsap\CACNA2D1, Hsap\CACNA2D4, Hsap\CACNA2D2, Hsap\CACNA2D3, Hsap\CACHD1" FBgn0000685 flrdH flight reduced H http://flybase.org/reports/FBgn0000685 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdH - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,heat sensitive,jumping defective,viable,reduced,male sterile,flight defective,courtship behavior defective" FBgn0265787 CR44576 - http://flybase.org/reports/FBgn0265787 non_protein_coding_gene - - - CR44576 - CR44576 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030013 GIIIspla2 Phospholipase A2 group III http://flybase.org/reports/FBgn0030013 protein_coding_gene phospholipase A2 activity ; GO:0004623 | inferred from electronic annotation with InterPro:IPR016090 phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090 - "BEST:HL07869, GIIIspla2, CG1583, Giiispla2, GIIIsPLA2" "IPR016090:Phospholipase A2 domain, IPR033113:Phospholipase A2, histidine active site" CG1583 11-Aug-17 DroID_v2017_08 "Drer\proca1, Drer\LOC101885160, Drer\zgc:123275" - - Xtro\proca1 "Mmus\Pla2g3, Mmus\Proca1" "Hsap\PROCA1, Hsap\PLA2G3" "viable,fertile" FBgn0023007 l(3)S113105 lethal (3) S113105 http://flybase.org/reports/FBgn0023007 - gene - - - "1131/5, 1131/05, l(3)S113105" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0021755 2R-F 2R-F http://flybase.org/reports/FBgn0021755 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 2R-F - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,viable,recessive" "wing,somatic clone" FBgn0041765 anon-d47 anon-d47 http://flybase.org/reports/FBgn0041765 gene - - - "d47, anon-d47" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021856 l(2)k14505 lethal (2) k14505 http://flybase.org/reports/FBgn0021856 FBgn0032937 protein_coding_gene - proton-transporting ATP synthase complex assembly ; GO:0043461 | inferred from electronic annotation with InterPro:IPR011419 - "l(2)k14505, CG8674" "IPR011419:ATP12, ATP synthase F1-assembly protein, IPR023335:Orthogonal Bundle domain in ATP12" CG8674 11-Aug-17 DroID_v2017_08 Drer\atpaf2 Scer\ATP12 Cele\Y116A8C.27 Xtro\atpaf2 Mmus\Atpaf2 Hsap\ATPAF2 "lethal,recessive,viable,fertile" FBgn0010141 l(2)DTS513 lethal (2) DTS513 http://flybase.org/reports/FBgn0010141 - gene - - - "DTS513, l(2)DTS513" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0266010 CR44783 - http://flybase.org/reports/FBgn0266010 non_protein_coding_gene - - - CR44783 - CR44783 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027360 Tim10 Translocase of inner membrane 10 http://flybase.org/reports/FBgn0027360 - protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with UniProtKB:P87108 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype protein import into mitochondrial inner membrane ; GO:0045039 | inferred from sequence or structural similarity with UniProtKB:P87108 negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype mitochondrial intermembrane space protein transporter complex ; GO:0042719 | inferred from sequence or structural similarity with UniProtKB:P87108 "CG9878, bs31d12.y1, tim10, Tim10, Dromel_CG9878_FBtr0071676_tim10_mORF" "IPR004217:Tim10/DDP family zinc finger, IPR027100:Mitochondrial import inner membrane translocase subunit Tim10" CG9878 11-Aug-17 DroID_v2017_08 Drer\timm10 "Scer\TIM10, Scer\TIM12" Cele\tin-10 Xtro\timm10 Mmus\Timm10 Hsap\TIMM10 "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0010358 deltaTry deltaTrypsin http://flybase.org/reports/FBgn0010358 - protein_coding_gene - - cytosol ; GO:0005829 | inferred from direct assay "CG12351, DmDeltaTry, delta, deltaTry, endo-I, Try" - CG12351 11-Aug-17 DroID_v2017_08 "Drer\tmprss4b, Drer\zgc:92590, Drer\zgc:112038, Drer\prss60.3, Drer\zgc:163079, Drer\prss60.2, Drer\si:dkeyp-93a5.2, Drer\try, Drer\prss60.1, Drer\zgc:153968, Drer\zgc:123295" - Cele\try-1 - "Mmus\Prss34, Mmus\Prss3, Mmus\Gm5771, Mmus\Gm10334, Mmus\Try4, Mmus\Try10, Mmus\2210010C04Rik, Mmus\Prss1, Mmus\Prss2, Mmus\Prss36, Mmus\Prss53" "Hsap\PRSS36, Hsap\PRSS3, Hsap\PRSS53, Hsap\PRSS1" DRSC07622 K -0.973581622 -0.953210578 -0.534894881 -0.190095294 0.64368416 -1.845562255 FBgn0027372 RevIII-7y RevIII-7y http://flybase.org/reports/FBgn0027372 - gene - - - RevIII-7y - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029722 CG7024 - http://flybase.org/reports/FBgn0029722 protein_coding_gene pyruvate dehydrogenase (acetyl-transferring) activity ; GO:0004739 | inferred from electronic annotation with InterPro:IPR017597 acetyl-CoA biosynthetic process from pyruvate ; GO:0006086 | inferred from electronic annotation with InterPro:IPR017597 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000162186 CG7024 "IPR001017:Dehydrogenase, E1 component, IPR017597:Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y, IPR029061:Thiamin diphosphate-binding fold" CG7024 11-Aug-17 DroID_v2017_08 "Drer\pdha1b, Drer\pdha1a" Scer\PDA1 Cele\pdha-1 Xtro\pdha1 "Mmus\Pdha1, Mmus\Pdha2" "Hsap\PDHA2, Hsap\PDHA1" viable FBgn0005206 l(3)DTS10 lethal (3) DTS10 http://flybase.org/reports/FBgn0005206 - gene - - - "DTS-10, l(3)DTS10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,female sterile" FBgn0010672 l(2)rJ235 lethal (2) rJ235 http://flybase.org/reports/FBgn0010672 - gene - - - l(2)rJ235 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000864 fs(1)M58 female sterile (1) M58 http://flybase.org/reports/FBgn0000864 - gene - - - fs(1)M58 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,recessive,heat sensitive,female sterile,some die during embryonic stage" egg FBgn0000471 Dly Delayed recovery http://flybase.org/reports/FBgn0000471 - gene - - - Dly - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0025674 CycK Cyclin K http://flybase.org/reports/FBgn0025674 "FBan0015218, FBgn0032975" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VP22 cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of phosphorylation of RNA polymerase II C-terminal domain ; GO:1901409 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 "CG15218, CycK" "IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like, IPR004367:Cyclin, C-terminal domain" CG15218 11-Aug-17 DroID_v2017_08 "Drer\ccnk, Drer\fam58a, Drer\ccnt1, Drer\ccnt2a, Drer\ccnt2b" "Scer\SSN8, Scer\CTK2" "Cele\cit-1.2, Cele\ccnk-1" "Xtro\ccnt1, Xtro\ccnk, Xtro\fam58a, Xtro\ccnt2" "Mmus\Ccnt2, Mmus\Tex24, Mmus\Fam58b, Mmus\Ccnt1, Mmus\Ccnk" "Hsap\CCNT1, Hsap\FAM58A, Hsap\CCNK, Hsap\CCNT2" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC03714 I -0.670065037 1.622417665 -0.424427973 0.619542827 -0.303414208 -0.450708288 FBgn0003610 Su(var)209 Suppressor of variegation 209 http://flybase.org/reports/FBgn0003610 - gene - - - "Su(var)209, 209" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,viable,non-suppressor of variegation" FBgn0086443 AsnRS Asparaginyl-tRNA synthetase http://flybase.org/reports/FBgn0086443 protein_coding_gene "asparagine-tRNA ligase activity ; GO:0004816 | inferred from electronic annotation with InterPro:IPR004522 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004364, InterPro:IPR004522, InterPro:IPR018150 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004365 asparagine-tRNA ligase activity ; GO:0004816 | traceable author statement" asparaginyl-tRNA aminoacylation ; GO:0006421 | inferred from electronic annotation with InterPro:IPR004522 asparaginyl-tRNA aminoacylation ; GO:0006421 | traceable author statement cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004522 cytoplasm ; GO:0005737 | traceable author statement "l(2)37Ca, CG10687, AsnRS, NRS, BcDNA:GH06451, Ca, l(2)E11, l(2)37Ca)E11, Aats-asn" "IPR012340:Nucleic acid-binding, OB-fold, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR004522:Asparagine-tRNA ligase, IPR004365:OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR004364:Aminoacyl-tRNA synthetase, class II (D/K/N), IPR002312:Aspartyl/Asparaginyl-tRNA synthetase, class IIb" CG10687 11-Aug-17 DroID_v2017_08 "Drer\nars2, Drer\nars, Drer\si:ch211-256m1.8" "Scer\DED81, Scer\SLM5" "Cele\nars-1, Cele\nars-2" Xtro\nars "Mmus\Nars2, Mmus\Nars" "Hsap\NARS2, Hsap\NARS" embryonic stage "

ubiquitous , embryonic/larval salivary gland

" FBgn0039563 CG4951 - http://flybase.org/reports/FBgn0039563 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4951 - CG4951 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0000799 fs(1)de10 female sterile (1) defective eggs 10 http://flybase.org/reports/FBgn0000799 - gene - - - "de10, fs(1)de10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" dorsal appendage FBgn0266708 Cep89 Centrosomal protein 89kDa http://flybase.org/reports/FBgn0266708 protein_coding_gene - cilium assembly ; GO:0060271 | inferred from electronic annotation with InterPro:IPR033545 chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from electronic annotation with InterPro:IPR033545 "Cep89, CG8214" IPR033545:Centrosomal protein of 89 kDa CG8214 11-Aug-17 DroID_v2017_08 Drer\cep89 - - Xtro\cep89 Mmus\Cep89 Hsap\CEP89 FBgn0015358 anon-9Bb anon-9Bb http://flybase.org/reports/FBgn0015358 - gene - - - anon-9Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035721 CG9948 - http://flybase.org/reports/FBgn0035721 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG9948 IPR006578:MADF domain CG9948 11-Aug-17 DroID_v2017_08 "Drer\zgc:152938, Drer\si:ch211-207i20.3, Drer\LOC100330838" - "Cele\madf-8, Cele\madf-5, Cele\madf-9, Cele\madf-3, Cele\madf-10, Cele\madf-4, Cele\madf-2" - - - viable FBgn0051195 CG31195 - http://flybase.org/reports/FBgn0051195 protein_coding_gene molecular_function ; GO:0003674 | no biological data available G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from biological aspect of ancestor with PANTHER:PTN002091395 plasma membrane ; GO:0005886 | inferred from direct assay "l(3)03806, CG31195" - CG31195 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-156l18.8, Drer\gpr158b, Drer\gpr158a" - "Cele\F39B2.8, Cele\trpl-3, Cele\trpl-4" Xtro\gpr158 "Mmus\Gpr158, Mmus\Gpr179" "Hsap\GPR179, Hsap\GPR158" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0065793 l(2)SH0420 lethal (2) SH0420 http://flybase.org/reports/FBgn0065793 gene - - - "l(2)SH0420, l(2)SH2 0420" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028705 Mtr1 Methyltransferase-related protein 1 http://flybase.org/reports/FBgn0028705 gene - - condensed chromosome ; GO:0000793 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "DmMTR1, Mtr1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037061 CG12975 - http://flybase.org/reports/FBgn0037061 protein_coding_gene - peptidyl-glutamine methylation ; GO:0018364 | inferred from biological aspect of ancestor with PANTHER:PTN000299384 tRNA methylation ; GO:0030488 | inferred from biological aspect of ancestor with PANTHER:PTN000299384 rRNA (guanine-N7)-methylation ; GO:0070476 | inferred from biological aspect of ancestor with PANTHER:PTN000299384 - "BcDNA:RE57810, CG12975" IPR005651:Uncharacterised protein family UPF0434/Trm112 CG12975 11-Aug-17 DroID_v2017_08 Drer\trmt112 Scer\TRM112 Cele\C04H5.1 Xtro\trmt112 Mmus\Trmt112 Hsap\TRMT112 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0035241 CG12105 - http://flybase.org/reports/FBgn0035241 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12105 - CG12105 11-Aug-17 DroID_v2017_08 - - Cele\com-1 - Mmus\Zc3h13 - viable FBgn0067101 GstD1::GstD2 GstD1::GstD2 http://flybase.org/reports/FBgn0067101 engineered_fusion_gene - - - GstD1::GstD2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032647 CG15143 - http://flybase.org/reports/FBgn0032647 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15143 "IPR032840:MAATS1 domain, IPR026720:Protein MAATS1" CG15143 11-Aug-17 DroID_v2017_08 Drer\maats1 - - Xtro\maats1 Mmus\Maats1 Hsap\MAATS1 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0051079 CG31079 - http://flybase.org/reports/FBgn0051079 protein_coding_gene - - - CG31079 - - 11-Aug-17 DroID_v2017_08 - - - - - - "body color defective,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum FBgn0265605 Ric Ras-related protein interacting with calmodulin http://flybase.org/reports/FBgn0265605 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Ras85D calmodulin binding ; GO:0005516 | traceable author statement calmodulin binding ; GO:0005516 | inferred from direct assay" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype response to osmotic stress ; GO:0006970 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 "CG8418, Q7JMZ0, 17137290, Ric, RIC, D-Ric, Roc" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR020849:Small GTPase superfamily, Ras type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8418 11-Aug-17 DroID_v2017_08 "Drer\rap1ab, Drer\si:ch73-116o1.2, Drer\zgc:153845, Drer\rras2, Drer\diras1b, Drer\zgc:55558, Drer\rasl11a, Drer\rap2c, Drer\diras2, Drer\si:dkeyp-59c12.1, Drer\rasd1, Drer\nras, Drer\hrasa, Drer\diras1a, Drer\rsg1, Drer\rerglb, Drer\ralbb, Drer\rap2ab, Drer\rheb, Drer\zgc:171704, Drer\LOC100332969, Drer\ralab, Drer\rem2, Drer\kras, Drer\ralaa, Drer\zgc:110699, Drer\gem, Drer\rit1, Drer\rras, Drer\zgc:114118, Drer\rasl12, Drer\rrad, Drer\ralba, Drer\rap1aa, Drer\rem1, Drer\rasl11b, Drer\si:dkey-27j5.5, Drer\hrasb, Drer\rergla, Drer\zgc:152698, Drer\rhebl1, Drer\rap2b, Drer\zgc:64022, Drer\rasl10a, Drer\mras" "Scer\RAS1, Scer\RSR1, Scer\RHB1, Scer\YHR022C, Scer\RAS2" "Cele\let-60, Cele\C44B7.12, Cele\ras-1, Cele\ral-1" "Xtro\diras3, Xtro\ras-dva, Xtro\rhebl1, Xtro\rheb, Xtro\rasl11b, Xtro\rem1, Xtro\rala, Xtro\rap1b, Xtro\rap2c, Xtro\diras1, Xtro\nras, Xtro\gem, Xtro\rap2a, Xtro\rergl, Xtro\rrad, Xtro\hras, Xtro\rerg, Xtro\kras, Xtro\rasl10a, Xtro\rap2b, Xtro\rasd1, Xtro\LOC733456, Xtro\rem2, Xtro\rit1, Xtro\ralb, Xtro\diras2, Xtro\rasd2, Xtro\adal, Xtro\rap1a, Xtro\rsg1" "Mmus\Rap2c, Mmus\Rap1b, Mmus\Rap2b, Mmus\Rem2, Mmus\Kras, Mmus\Rsg1, Mmus\Rap1a, Mmus\Rergl, Mmus\Rasl12, Mmus\Rasl11b, Mmus\Hras, Mmus\Gm266, Mmus\Rasd2, Mmus\Rala, Mmus\Rasl10b, Mmus\Diras1, Mmus\Mras, Mmus\Rhebl1, Mmus\Rit2, Mmus\Rasl11a, Mmus\Adal, Mmus\Rit1, Mmus\Rras2, Mmus\Rasl10a, Mmus\Rras, Mmus\Rerg, Mmus\Ralb, Mmus\Rem1, Mmus\Rasd1, Mmus\Rrad, Mmus\Rap2a, Mmus\Gem, Mmus\Rheb, Mmus\Diras2, Mmus\Nras, Mmus\Eras" "Hsap\RIT2, Hsap\RAP1B, Hsap\GEM, Hsap\RIT1, Hsap\ERAS, Hsap\RAP2A, Hsap\DIRAS2, Hsap\DIRAS3, Hsap\RERGL, Hsap\HRAS, Hsap\RHEB, Hsap\MRAS, Hsap\DIRAS1, Hsap\RASD1, Hsap\REM2, Hsap\RAP2C, Hsap\RHEBL1, Hsap\NRAS, Hsap\KRAS, Hsap\REM1, Hsap\RAP2B, Hsap\RASL10A, Hsap\RRAS2, Hsap\RASL10B, Hsap\RERG, Hsap\RASL12, Hsap\RALA, Hsap\RAP1A, Hsap\RALB, Hsap\RRAD, Hsap\RRAS, Hsap\RASD2, Hsap\RSG1, Hsap\RASL11A, Hsap\RASL11B" FBgn0259101 CG42249 - http://flybase.org/reports/FBgn0259101 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR006146 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR006146 nucleoside-triphosphatase activity ; GO:0017111 | inferred from direct assay nucleoside-diphosphatase activity ; GO:0017110 | inferred from direct assay 5'-nucleotidase activity ; GO:0008253 | NOT inferred from direct assay "nucleotide catabolic process ; GO:0009166 | inferred from electronic annotation with InterPro:IPR006179, InterPro:IPR008334" - "CG42249, CG1961, CG11126" "IPR006146:5'-Nucleotidase, conserved site, IPR006179:5'-Nucleotidase/apyrase, IPR008334:5'-Nucleotidase, C-terminal, IPR029052:Metallo-dependent phosphatase-like" CG42249 11-Aug-17 DroID_v2017_08 Drer\nt5e Scer\YHR202W - Xtro\nt5e "Mmus\Nt5e, Mmus\4933425L06Rik" Hsap\NT5E FBgn0052175 CG32175 - http://flybase.org/reports/FBgn0052175 protein_coding_gene - - - CG32175 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065107 snmRNA:128 small non-messenger RNA 128 http://flybase.org/reports/FBgn0065107 non_protein_coding_gene - - - "Dm-128, CR33915, snmRNA:128" - CR33915 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005408 l(1)11Ah lethal (1) 11Ah http://flybase.org/reports/FBgn0005408 - gene - - - l(1)11Ah - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086291 GS5071 - http://flybase.org/reports/FBgn0086291 gene - - - "GS5071, 5071" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025877 opus\env opus element env http://flybase.org/reports/FBgn0025877 - transposable_element_gene - - - "ORF3, yoyo\env, yoyo\Env, opus\env, env" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267757 CR46088 - http://flybase.org/reports/FBgn0267757 non_protein_coding_gene - - - CR46088 - CR46088 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036621 roq roquin http://flybase.org/reports/FBgn0036621 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:21461 zinc ion binding ; GO:0008270 | inferred from sequence model RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:21461 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:21461 cytoplasmic stress granule ; GO:0010494 | inferred from direct assay "NEST:bs21b12, CG16807, roq" "IPR000571:Zinc finger, CCCH-type, IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG16807 11-Aug-17 DroID_v2017_08 "Drer\rc3h1a, Drer\rc3h2, Drer\rc3h1b" - "Cele\rle-1, Cele\Y6D1A.2, Cele\C28G1.5" Xtro\rc3h1 "Mmus\Rc3h2, Mmus\Rc3h1, Mmus\Nhlrc1" "Hsap\NHLRC1, Hsap\RC3H1, Hsap\RC3H2" "viable,fertile" FBgn0041257 E(Src64)2B E(Src64)2B http://flybase.org/reports/FBgn0041257 gene - - - E(Src64)2B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063757 CR32366 - http://flybase.org/reports/FBgn0063757 non_protein_coding_gene - - - "BcDNA:AT05287, CR32366" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051122 CG31122 - http://flybase.org/reports/FBgn0051122 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG7687, CG14308, CG31122" "IPR018881:Uncharacterised protein family UPF0565, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG31122 11-Aug-17 DroID_v2017_08 Drer\zgc:153521 - - Xtro\c2orf69 Mmus\1700066M21Rik Hsap\C2orf69 "viable,fertile,long lived,visible" "chaeta,supernumerary,trichogen cell" DRSC14787 IE -1.865577931 -4.524854393 -1.208602766 -5.085351401 -0.944574426 -0.6760163 FBgn0060397 l(3)S132214 lethal (3) S132214 http://flybase.org/reports/FBgn0060397 gene - - - "1322/14, l(3)S132214" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0052371 CG32371 - http://flybase.org/reports/FBgn0052371 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR004953, InterPro:IPR027328" - - "EB1, BEST:GH23475, CG32371" "IPR001715:Calponin homology domain, IPR004953:EB1, C-terminal, IPR027328:Microtubule-associated protein RP/EB" CG32371 11-Aug-17 DroID_v2017_08 "Drer\mapre1b, Drer\mapre3b, Drer\mapre2, Drer\mapre3a, Drer\mapre1a" Scer\BIM1 "Cele\ebp-3, Cele\ebp-1, Cele\ebp-2" Xtro\mapre1 "Mmus\Mapre3, Mmus\Mapre1, Mmus\Mapre2" "Hsap\MAPRE3, Hsap\MAPRE1, Hsap\MAPRE2" viable FBgn0011017 l(3)s2017 lethal (3) s2017 http://flybase.org/reports/FBgn0011017 - gene - - - l(3)s2017 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264443 CG43861 - http://flybase.org/reports/FBgn0264443 protein_coding_gene - - - "CG43861, CG13966, CG12508" - CG43861 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085457 CG34428 - http://flybase.org/reports/FBgn0085457 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34428, CG14116" IPR006631:Protein of unknown function DM4/12 CG34428 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038108 CG7518 - http://flybase.org/reports/FBgn0038108 protein_coding_gene - - - CG7518 "IPR029717:FAM193 family, IPR015943:WD40/YVTN repeat-like-containing domain" CG7518 11-Aug-17 DroID_v2017_08 "Drer\fam193b, Drer\fam193a" - - - "Mmus\Fam193b, Mmus\Fam193a" "Hsap\FAM193B, Hsap\FAM193A" viable DRSC16253 I 1.666185537 -0.483092391 -0.169998659 -0.355073216 0.284368513 0.544138965 FBgn0263973 jv javelin http://flybase.org/reports/FBgn0263973 protein_coding_gene - chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype parallel actin filament bundle assembly ; GO:0030046 | inferred from mutant phenotype actin filament bundle ; GO:0032432 | colocalizes_with inferred from direct assay "jv, CG32397, anon-WO0138581.6" - CG32397 11-Aug-17 DroID_v2017_08 - - - - - - visible "denticle belt,macrochaeta,microchaeta,posterior scutellar bristle,actin filament bundle,nurse cell" FBgn0029013 l(3)77CDl lethal (3) 77CDl http://flybase.org/reports/FBgn0029013 gene - - - l(3)77CDl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002842 sa spermatocyte arrest http://flybase.org/reports/FBgn0002842 FBgn0037080 protein_coding_gene - spermatid development ; GO:0007286 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | traceable author statement male meiosis I ; GO:0007141 | inferred from mutant phenotype transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:17300 nucleolus ; GO:0005730 | inferred from direct assay male germ cell nucleus ; GO:0001673 | inferred from direct assay "sa, dTAF8L, CG11308, ms(3)sa, TAF8L, ms(3)VO5, ms(3)VO45, gfb, TAF-like, tTAF, Sa" "IPR006565:Bromodomain associated domain, IPR019473:Transcription factor TFIID, subunit 8, C-terminal" CG11308 11-Aug-17 DroID_v2017_08 Drer\taf8 "Scer\TAF8, Scer\TAF3" "Cele\taf-8, Cele\phf-34, Cele\Y54E2A.8" Xtro\taf8 Mmus\Taf8 Hsap\TAF8 "male sterile,recessive,meiotic cell cycle defective,viable" "testis,spermatocyte" FBgn0038420 CG10311 - http://flybase.org/reports/FBgn0038420 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from sequence model "gh22794, BEST:GH22794, CG10311, dmCG10311" IPR031720:Protein of unknown function DUF4728 CG10311 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0003438 smd smalloid http://flybase.org/reports/FBgn0003438 - gene - - - smd - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective,viable,fertile" eye FBgn0032775 CG17544 - http://flybase.org/reports/FBgn0032775 protein_coding_gene acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012258 acyl-CoA oxidase activity ; GO:0003997 | inferred from sequence or structural similarity with HGNC:119 fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:119 "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:119,HGNC:120 inferred from sequence model inferred from direct assay" CG17544 "IPR002655:Acyl-CoA oxidase, C-terminal, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR012258:Acyl-CoA oxidase, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR034171:Peroxisomal acyl-coenzyme A oxidase" CG17544 11-Aug-17 DroID_v2017_08 "Drer\acox1, Drer\acox3, Drer\acoxl" Scer\POX1 "Cele\acox-6, Cele\F59F4.1" "Xtro\acox3, Xtro\acox2, Xtro\acox1" "Mmus\Acox1, Mmus\Acox2, Mmus\Acoxl, Mmus\Acox3" "Hsap\ACOX2, Hsap\ACOXL, Hsap\ACOX3, Hsap\ACOX1" "viable,fertile" FBgn0037714 CG9396 - http://flybase.org/reports/FBgn0037714 protein_coding_gene pyruvate transmembrane transporter activity ; GO:0050833 | inferred from biological aspect of ancestor with PANTHER:PTN000365945 pyruvate transmembrane transporter activity ; GO:0050833 | inferred from sequence or structural similarity with SGD:S000001205 mitochondrial pyruvate transmembrane transport ; GO:1902361 | inferred from biological aspect of ancestor with PANTHER:PTN000365945 mitochondrial pyruvate transport ; GO:0006850 | inferred from sequence or structural similarity with SGD:S000003048 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of mitochondrial inner membrane ; GO:0031305 | inferred from sequence or structural similarity with SGD:S000001205 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000365945 CG9396 IPR005336:Mitochondrial pyruvate carrier CG9396 11-Aug-17 DroID_v2017_08 "Drer\mpc2, Drer\zgc:103678" "Scer\MPC2, Scer\MPC3" Cele\F53F10.3 Xtro\mpc2 Mmus\Mpc2 Hsap\MPC2 FBgn0067629 CG33332 - http://flybase.org/reports/FBgn0067629 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3641, BcDNA:RE07395, CG33332" IPR022226:Protein of unknown function DUF3752 CG33332 11-Aug-17 DroID_v2017_08 "Drer\gpalpp1, Drer\tamm41" Scer\TAM41 Cele\F26A3.7 "Xtro\tamm41, Xtro\gpalpp1" "Mmus\Tamm41, Mmus\Gpalpp1" "Hsap\GPALPP1, Hsap\TAMM41" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0001343 l(1)1Ca lethal (1) 1Ca http://flybase.org/reports/FBgn0001343 - gene - - - l(1)1Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage,recessive" FBgn0036271 Pbgs Porphobilinogen synthase http://flybase.org/reports/FBgn0036271 protein_coding_gene porphobilinogen synthase activity ; GO:0004655 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000156046 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000156046 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000156046 "DmPBGS, CG10335, Pbgs, delta-ALA-D" "IPR001731:Delta-aminolevulinic acid dehydratase, IPR013785:Aldolase-type TIM barrel, IPR030656:Delta-aminolevulinic acid dehydratase, active site" CG10335 11-Aug-17 DroID_v2017_08 Drer\alad Scer\HEM2 "Cele\ZK1025.8, Cele\ZK1025.2" Xtro\alad Mmus\Alad Hsap\ALAD "viable,lethal" FBgn0037470 Tailor Tailor http://flybase.org/reports/FBgn0037470 protein_coding_gene RNA uridylyltransferase activity ; GO:0050265 | inferred from direct assay RNA 3' uridylation ; GO:0071076 | inferred from mutant phenotype pre-miRNA processing ; GO:0031054 | inferred from mutant phenotype - "anon-WO0118547.222, CG1091, Tailor" IPR002058:PAP/25A-associated CG1091 11-Aug-17 DroID_v2017_08 "Drer\zcchc6, Drer\tut1, Drer\papd4, Drer\mtpap, Drer\zcchc11" - "Cele\pup-2, Cele\gld-2, Cele\pup-3, Cele\T08B2.4, Cele\R07H5.11, Cele\usip-1, Cele\F31C3.2, Cele\Y34F4.3, Cele\F43H9.3, Cele\F43E2.1, Cele\C53A5.16, Cele\mut-2, Cele\cid-1" "Xtro\zcchc11, Xtro\mtpap, Xtro\zcchc6, Xtro\tut1, Xtro\papd4" "Mmus\Tut1, Mmus\Papd4, Mmus\Mtpap, Mmus\Zcchc11, Mmus\Zcchc6" "Hsap\PAPD4, Hsap\MTPAP, Hsap\ZCCHC11, Hsap\TUT1, Hsap\ZCCHC6" viable FBgn0015375 cub currant bun http://flybase.org/reports/FBgn0015375 FBgn0002025 gene - - - "l(2)37Bg, Bg, cub" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,lethal,recessive" "melanotic mass,pupa,pupal cuticle,wing disc,ventral thoracic disc" FBgn0033355 CG13748 - http://flybase.org/reports/FBgn0033355 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG13748 "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG13748 11-Aug-17 DroID_v2017_08 "Drer\aplp2, Drer\aplp1, Drer\si:dkey-117n7.5, Drer\appb, Drer\appa" - "Cele\Y43F8B.3, Cele\piit-1, Cele\Y49G5A.1, Cele\R12A1.3, Cele\apl-1, Cele\C34F6.1" "Xtro\app, Xtro\aplp1, Xtro\aplp2" "Mmus\Spint3, Mmus\Wfdc3, Mmus\App, Mmus\Spint1, Mmus\Spint2, Mmus\Wfdc8, Mmus\Aplp1, Mmus\Wfdc2, Mmus\Kirrel2, Mmus\Aplp2" "Hsap\WFDC3, Hsap\WFDC2, Hsap\SPINT2, Hsap\WFDC8, Hsap\SPINT1, Hsap\KIRREL2, Hsap\APLP1, Hsap\APLP2, Hsap\APP" viable DRSC06419 I 1.879083553 -0.091678368 0.421111536 0.188996947 0.770909311 0.331354923 FBgn0263781 CG41057 - http://flybase.org/reports/FBgn0263781 protein_coding_gene - - - "CG41057, CG40157" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266561 EP2173 - http://flybase.org/reports/FBgn0266561 gene - - - EP2173 - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval salivary gland FBgn0014191 hobo\T hobo element transposase http://flybase.org/reports/FBgn0014191 - transposable_element_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR008906 - - "H\T, hobo\T" "IPR018473:Hermes trasposase, DNA-binding domain, IPR008906:HAT, C-terminal dimerisation domain, IPR012337:Ribonuclease H-like domain, IPR003656:Zinc finger, BED-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050429 CG30429 - http://flybase.org/reports/FBgn0050429 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG30429, Q8MLN3_DROME" IPR003409:MORN motif CG30429 11-Aug-17 DroID_v2017_08 "Drer\jph2, Drer\jph1a, Drer\als2b, Drer\morn4, Drer\rsph1, Drer\morn3, Drer\si:ch211-146m13.3, Drer\jph1b, Drer\jph3, Drer\als2a, Drer\rsph10b" - - "Xtro\jph1, Xtro\als2, Xtro\rsph1, Xtro\morn3, Xtro\morn5, Xtro\jph2, Xtro\rsph10b, Xtro\als2cl" "Mmus\Morn5, Mmus\Rsph1, Mmus\Morn4, Mmus\Morn1, Mmus\Jph1, Mmus\Jph2, Mmus\Als2cl, Mmus\Als2, Mmus\Jph4, Mmus\Morn3, Mmus\Jph3" "Hsap\MORN3, Hsap\ALS2, Hsap\JPH2, Hsap\JPH3, Hsap\JPH1, Hsap\MORN4, Hsap\ALS2CL, Hsap\JPH4, Hsap\MORN5, Hsap\RSPH10B2, Hsap\RSPH10B, Hsap\RSPH1, Hsap\MORN1" viable FBgn0034105 CG7755 - http://flybase.org/reports/FBgn0034105 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR024084" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR024084 chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp inferred from genetic interaction with Chi" - CG7755 IPR024084:Isopropylmalate dehydrogenase-like domain CG7755 11-Aug-17 DroID_v2017_08 "Drer\idh3b, Drer\zgc:165532, Drer\idh3g" "Scer\IDH2, Scer\LEU2, Scer\IDH1, Scer\LYS12" "Cele\idha-1, Cele\idhg-2, Cele\idhg-1" "Xtro\idh3g, Xtro\idh3b" "Mmus\4933405O20Rik, Mmus\Idh3b, Mmus\Idh3a, Mmus\Idh3g" "Hsap\IDH3G, Hsap\IDH3A, Hsap\IDH3B" viable FBgn0060677 l(3)S077213 lethal (3) S077213 http://flybase.org/reports/FBgn0060677 gene - - - "0772/13, l(3)S077213" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026440 EY3-5 EY3-5 http://flybase.org/reports/FBgn0026440 - gene - - - EY3-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004824 fs(2)ltoPI23 female sterile (2) ltoPI23 http://flybase.org/reports/FBgn0004824 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Pl23, fs(2)ltoPI23" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015410 l(1)14ABa lethal (1) 14ABa http://flybase.org/reports/FBgn0015410 - gene - - - l(1)14ABa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267690 CG46026 - http://flybase.org/reports/FBgn0267690 protein_coding_gene - - - "CG46026, CG31556, mdcds_43655" - CG46026 11-Aug-17 DroID_v2017_08 - Scer\PRM7 Cele\F59A6.3 - - - FBgn0060362 l(3)S138901b lethal (3) S138901b http://flybase.org/reports/FBgn0060362 gene - - - "1389/01, l(3)S138901b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0042680 Rt1b\gag Rt1b element gag http://flybase.org/reports/FBgn0042680 transposable_element_gene - - - "ORF1, Waldo-A\gag, Rt1b\gag, Rt1b/gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033607 CG9062 - http://flybase.org/reports/FBgn0033607 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000003648 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:30914 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:30914 CG9062 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like, IPR021772:Protein of unknown function DUF3337" CG9062 11-Aug-17 DroID_v2017_08 "Drer\wdr48b, Drer\LOC100534785, Drer\wdr48a" "Scer\MDV1, Scer\PWP2, Scer\DUF1, Scer\CAF4" Cele\wdr-48 Xtro\wdr48 Mmus\Wdr48 Hsap\WDR48 viable FBgn0264884 CR44075 - http://flybase.org/reports/FBgn0264884 non_protein_coding_gene - - - CR44075 - CR44075 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265159 CR44228 - http://flybase.org/reports/FBgn0265159 non_protein_coding_gene - - - CR44228 - CR44228 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031159 CG11566 - http://flybase.org/reports/FBgn0031159 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32514, CG11569, CG11566" - CG11566 11-Aug-17 DroID_v2017_08 "Drer\cacng4a, Drer\cacng7a, Drer\cacng2a, Drer\cacng1b, Drer\cacng5b, Drer\cacng7b, Drer\cacng3a, Drer\cacng8b, Drer\cacng4b, Drer\cacng5a, Drer\si:ch73-369d14.2, Drer\cacng3b, Drer\cacng8a" - "Cele\stg-2, Cele\stg-1, Cele\D1007.8" "Xtro\cacng4, Xtro\cacng8, Xtro\cacng3, Xtro\cacng7" "Mmus\Cacng8, Mmus\Cacng4, Mmus\Cacng7, Mmus\Tmem114, Mmus\Cacng5, Mmus\Cacng2, Mmus\Cacng3" "Hsap\CACNG3, Hsap\CACNG5, Hsap\CACNG4, Hsap\CACNG2, Hsap\CACNG8, Hsap\CACNG7" "viable,fertile" FBgn0084638 su(eas)7 su(eas)7 http://flybase.org/reports/FBgn0084638 gene - - - su(eas)7 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010786 l(3)02640 lethal (3) 02640 http://flybase.org/reports/FBgn0010786 "FBgn0011370, FBgn0035212, FBgn0045880" protein_coding_gene hydroxymethylbilane synthase activity ; GO:0004418 | inferred from biological aspect of ancestor with PANTHER:PTN000168159 peptidyl-pyrromethane cofactor linkage ; GO:0018160 | inferred from electronic annotation with InterPro:IPR022419 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000168159 sleep ; GO:0030431 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000168159 "CG9165, l(3)3544, 3544, 2640, l(3)j4E3, anon-WO0153538.70, l(3)02640, l(3)7E130, PBGD" "IPR000860:Porphobilinogen deaminase, IPR022417:Porphobilinogen deaminase, N-terminal, IPR022418:Porphobilinogen deaminase, C-terminal, IPR022419:Porphobilinogen deaminase, dipyrromethane cofactor binding site" CG9165 11-Aug-17 DroID_v2017_08 "Drer\hmbsb, Drer\hmbsa" Scer\HEM3 - Xtro\hmbs Mmus\Hmbs Hsap\HMBS "lethal,viable,fertile,recessive" FBgn0052224 CR32224 - http://flybase.org/reports/FBgn0052224 non_protein_coding_gene - - - "CR32224, CG32224" - CR32224 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034837 RpL22-like Ribosomal protein L22-like http://flybase.org/reports/FBgn0034837 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR002671 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002671 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "RpL22-like, CG9871, rpL22-like" IPR002671:Ribosomal protein L22e CG9871 11-Aug-17 DroID_v2017_08 "Drer\rpl22l1, Drer\rpl22" "Scer\RPL22B, Scer\RPL22A" Cele\rpl-22 "Xtro\rpl22, Xtro\rpl22l1" "Mmus\Rpl22l1, Mmus\Rpl22" "Hsap\RPL22L1, Hsap\RPL22" DRSC04582 K -0.628549451 0.675142498 -0.444610541 -0.057231442 1.653236274 -0.953135268 FBgn0041727 Rt1a\gag Rt1a element gag http://flybase.org/reports/FBgn0041727 transposable_element_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - "ORF1, pilger\gag, Waldo-B\gag, Rt1a\gag" "IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069156 mcl(3)Z2585 mcl(3)Z2585 http://flybase.org/reports/FBgn0069156 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z2585 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0028947 CG11865 - http://flybase.org/reports/FBgn0028947 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" - "BACR44L22.4, BG:BACR44L22.4, CG11865" "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG11865 11-Aug-17 DroID_v2017_08 "Drer\he2, Drer\he1a, Drer\bmp1b, Drer\c6ast1, Drer\tnfaip6, Drer\LOC797085, Drer\c6ast4, Drer\LOC100003133, Drer\npsn, Drer\mep1a.2, Drer\mep1a.1, Drer\bmp1a, Drer\mep1b, Drer\si:ch73-40a17.3, Drer\he1b, Drer\c6ast3, Drer\tll1" - "Cele\nas-38, Cele\nas-39, Cele\nas-1, Cele\Y19D10A.6, Cele\nas-24, Cele\nas-13, Cele\toh-1, Cele\nas-12, Cele\nas-22, Cele\nas-4, Cele\nas-6, Cele\nas-19, Cele\nas-2, Cele\ZC116.3, Cele\nas-8, Cele\nas-7, Cele\nas-28, Cele\nas-33, Cele\nas-15, Cele\nas-14, Cele\nas-21" "Xtro\accs, Xtro\tll1, Xtro\tll2, Xtro\uvs.2, Xtro\mep1b, Xtro\LOC100492324, Xtro\cubn, Xtro\tnfaip6, Xtro\bmp1, Xtro\mep1a, Xtro\LOC100489456" "Mmus\Mep1b, Mmus\Cubn, Mmus\Tnfaip6, Mmus\Adgrg6, Mmus\Tll1, Mmus\Tll2, Mmus\Bmp1, Mmus\Mep1a, Mmus\Astl" "Hsap\ASTL, Hsap\ADGRG6, Hsap\TNFAIP6, Hsap\BMP1, Hsap\TLL2, Hsap\TLL1, Hsap\MEP1A, Hsap\CUBN, Hsap\MEP1B" viable FBgn0266557 kis kismet http://flybase.org/reports/FBgn0266557 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 DNA-dependent ATPase activity ; GO:0008094 | inferred from sequence or structural similarity with HGNC:20153 "positive regulation of organ growth ; GO:0046622 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern positive regulation of receptor localization to synapse ; GO:1902685 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype ATP-dependent chromatin remodeling ; GO:0043044 | inferred from direct assay short-term memory ; GO:0007614 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "KIS, EC2-7, kis, Kis, EP(2)0474, EP474, FBtr0078144, kiss, CG3660, EK2-4, l(2)k16510, GM02209, 5841, 2532, 136/31, l(2)k14112, l(2)k13631, l(2)k11324, l(2)s4793, l(2)s4771, l(2)s3527, l(2)k08827, l(2)07812, Su(Pc)21AB, CG18326, CG3696, BEST:GM02209, anon-WO0257455.5, anon-WO0172774.164, KIS-L, DmelPex20, Pex20" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000330:SNF2-related, N-terminal domain, IPR000953:Chromo/chromo shadow domain, IPR001650:Helicase, C-terminal, IPR006576:BRK domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR016197:Chromo domain-like, IPR023780:Chromo domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG3696 11-Aug-17 DroID_v2017_08 "Drer\chd6, Drer\chd1, Drer\chd9, Drer\si, Drer\chd2, Drer\chd7, Drer\chd8" Scer\CHD1 Cele\chd-7 "Xtro\chd8, Xtro\chd6, Xtro\chd1, Xtro\chd2, Xtro\chd9" "Mmus\Ep400, Mmus\Chd9, Mmus\Chd7, Mmus\Chd6, Mmus\1700125H20Rik, Mmus\Chd8" "Hsap\C17orf64, Hsap\EP400, Hsap\CHD7, Hsap\CHD9, Hsap\CHD6, Hsap\CHD8" DRSC00625 IK 1.083501426 -1.973909437 0.711314895 0.462711635 0.317857778 2.555470177 FBgn0031478 CG8814 - http://flybase.org/reports/FBgn0031478 protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 - - CG8814 "IPR000582:Acyl-CoA-binding protein, ACBP, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle" CG8814 11-Aug-17 DroID_v2017_08 "Drer\zgc:92030, Drer\dbi, Drer\acbd5a, Drer\acbd5b, Drer\acbd7, Drer\acbd6, Drer\mettl23, Drer\LOC103909942, Drer\acbd4" Scer\ACB1 "Cele\acbp-4, Cele\acbp-3, Cele\maa-1, Cele\acbp-6, Cele\acbp-5" "Xtro\acbd5, Xtro\acbd7, Xtro\mettl23, Xtro\acbd6, Xtro\eci2" "Mmus\Mettl23, Mmus\Acbd7, Mmus\Dbi, Mmus\Dbil5, Mmus\Acbd4, Mmus\Acbd6, Mmus\Eci2, Mmus\Acbd5" "Hsap\METTL23, Hsap\ACBD4, Hsap\ACBD5, Hsap\DBI, Hsap\ACBD7, Hsap\ACBD6, Hsap\ECI2" "viable,fertile" FBgn0022320 l(1)B64.2 lethal (1) B64.2 http://flybase.org/reports/FBgn0022320 - gene - - - l(1)B64.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040931 CG9034 - http://flybase.org/reports/FBgn0040931 protein_coding_gene - - - "GH20078, BcDNA:RH45008, CG9034" - CG9034 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0069905 CR41115 - http://flybase.org/reports/FBgn0069905 non_protein_coding_gene - - - CR41115 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015256 M(2)92 M(2)92 http://flybase.org/reports/FBgn0015256 - gene - - - M(2)92 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,Minute" FBgn0029096 ap::Chi ap::Chi http://flybase.org/reports/FBgn0029096 engineered_fusion_gene - - - ap::Chi - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,ventral compartment,wing margin,ectopic,dorsal compartment" FBgn0050181 ppk3 pickpocket 3 http://flybase.org/reports/FBgn0050181 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "cg30181, CG15872, CG30181, ppk3" IPR001873:Epithelial sodium channel CG30181 11-Aug-17 DroID_v2017_08 "Drer\asic1a, Drer\asic4a, Drer\asic1c, Drer\asic2, Drer\asic1b, Drer\asic4b" - "Cele\acd-1, Cele\del-7, Cele\del-8, Cele\acd-3, Cele\flr-1, Cele\acd-2, Cele\delm-1, Cele\acd-4, Cele\delm-2, Cele\acd-5" "Xtro\scnn1d, Xtro\scnn1a, Xtro\scnn1g, Xtro\asic4, Xtro\asic5, Xtro\asic1, Xtro\scnn1b" "Mmus\Asic1, Mmus\Asic5, Mmus\Asic3, Mmus\Scnn1b, Mmus\Scnn1a, Mmus\Scnn1g, Mmus\Asic4, Mmus\Asic2" "Hsap\ASIC1, Hsap\ASIC4, Hsap\SCNN1G, Hsap\ASIC5, Hsap\SCNN1B, Hsap\SCNN1D, Hsap\ASIC2, Hsap\SCNN1A, Hsap\ASIC3" FBgn0040718 CG15353 - http://flybase.org/reports/FBgn0040718 protein_coding_gene - - - "BcDNA:RH63135, CG15353" - CG15353 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0086670 snoRNA:Psi28S-2622 snoRNA:Psi28S-2622 http://flybase.org/reports/FBgn0086670 snoRNA_gene - - - "psi28s-2622, snoRNA:3, Dm-3, snoR3, CR33656, Psi28S-2622(SnoR3), snoRNA:Psi28S-2622, Psi28S-2622, chr3L:1472428..1472587" - CR33656 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032593 Trpgamma Transient receptor potential cation channel gamma http://flybase.org/reports/FBgn0032593 protein_coding_gene mechanically gated channel activity ; GO:0022833 | inferred from direct assay cation channel activity ; GO:0005261 | inferred from direct assay store-operated calcium channel activity ; GO:0015279 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P19334 inferred from physical interaction with UniProtKB:P48994 calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity with UniProtKB:P19334 calcium ion transmembrane transport ; GO:0070588 | inferred from electronic annotation with InterPro:IPR002153 response to light stimulus ; GO:0009416 | inferred from sequence or structural similarity with UniProtKB:P19334 detection of light stimulus involved in visual perception ; GO:0050908 | inferred from sequence or structural similarity with UniProtKB:P19334 regulation of cytosolic calcium ion concentration ; GO:0051480 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 cation transport ; GO:0006812 | inferred from direct assay calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity with UniProtKB:P19334 response to light stimulus ; GO:0009416 | traceable author statement neuromuscular process controlling posture ; GO:0050884 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype manganese ion transport ; GO:0006828 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 cation channel complex ; GO:0034703 | inferred from physical interaction with trpl rhabdomere ; GO:0016028 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 proximal dendrite ; GO:1990635 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "dTRPgamma, TRPgamma, dTRPg, trp-gamma, CG5996, trpgamma, Trpgamma, DmTRPgamma, Trp-gamma" "IPR002110:Ankyrin repeat, IPR002153:Transient receptor potential channel, canonical, IPR004729:Transient receptor potential channel, IPR005821:Ion transport domain, IPR013555:Transient receptor ion channel domain, IPR020683:Ankyrin repeat-containing domain" CG5996 11-Aug-17 DroID_v2017_08 "Drer\trpc3, Drer\trpc6a, Drer\trpc4b, Drer\trpc7a, Drer\trpc4a, Drer\zgc:110224, Drer\trpn1, Drer\trpc1, Drer\trpc2b, Drer\trpc2a, Drer\trpc5a" Scer\YVC1 "Cele\trp-2, Cele\trp-1, Cele\spe-41" "Xtro\trpc2, Xtro\trpc1, Xtro\trpc6, Xtro\trpc3, Xtro\trpc5, Xtro\LOC100492885, Xtro\trpc4" "Mmus\Trpc4, Mmus\Trpc2, Mmus\Trpc7, Mmus\Trpc3, Mmus\Trpc1, Mmus\Trpc5, Mmus\Trpc6" "Hsap\TRPC4, Hsap\TRPC7, Hsap\TRPC6, Hsap\TRPC3, Hsap\TRPC1, Hsap\TRPC5" "partially lethal - majority die,some die during pupal stage,viable,lethal" FBgn0036096 CG8003 - http://flybase.org/reports/FBgn0036096 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8003 "IPR002110:Ankyrin repeat, IPR002893:Zinc finger, MYND-type, IPR020683:Ankyrin repeat-containing domain" CG8003 11-Aug-17 DroID_v2017_08 "Drer\ankmy2b, Drer\ankmy2a" - Cele\daf-25 Xtro\ankmy2 "Mmus\Ankmy2, Mmus\Invs" "Hsap\ANKMY2, Hsap\ANKRD33, Hsap\ANKRD45, Hsap\INVS" "partially lethal - majority die,some die during pupal stage" FBgn0022108 l(2)k07005 lethal (2) k07005 http://flybase.org/reports/FBgn0022108 - gene - - - l(2)k07005 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0063421 l(3)3450-B lethal (3) 3450-B http://flybase.org/reports/FBgn0063421 gene - - - l(3)3450-B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0032481 CG16972 - http://flybase.org/reports/FBgn0032481 protein_coding_gene - - - "anon-WO0140519.52, CG16972" - CG16972 11-Aug-17 DroID_v2017_08 - - - - - - viable rhabdomere R7 FBgn0051683 CG31683 - http://flybase.org/reports/FBgn0051683 protein_coding_gene O-acyltransferase activity ; GO:0008374 | inferred from electronic annotation with InterPro:IPR003386 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR003386 - "BcDNA:GH02384, CG31683" "IPR003386:Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase, IPR029058:Alpha/Beta hydrolase fold" CG31683 11-Aug-17 DroID_v2017_08 "Drer\lcat, Drer\pla2g15" "Scer\YJR098C, Scer\TGL2, Scer\LRO1" Cele\M05B5.4 "Xtro\pla2g15, Xtro\lcat" "Mmus\Lcat, Mmus\Pla2g15" "Hsap\LCAT, Hsap\PLA2G15" FBgn0050476 ave aveugle http://flybase.org/reports/FBgn0050476 protein_coding_gene - positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from direct assay eye photoreceptor cell differentiation ; GO:0001754 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG30476, BcDNA:RE67675, ave, HYP, CG30476/Ave, hyp" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG30476 11-Aug-17 DroID_v2017_08 "Drer\samd10a, Drer\samd10b, Drer\samd12" - Cele\ave-1 - "Mmus\Samd12, Mmus\Samd10" "Hsap\SAMD12, Hsap\SAMD10, Hsap\SAMD15" "increased cell death,somatic clone,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during third instar larval stage,viable" "photoreceptor cell R1,somatic clone,photoreceptor cell R6,photoreceptor cell R4,photoreceptor cell R3,cone cell,wing vein,wing disc" DRSC05502 IEK -0.783151309 -4.087557387 -0.368421198 -3.574424588 -1.561886618 -1.297273331 FBgn0260383 GSd319 - http://flybase.org/reports/FBgn0260383 gene - - - GSd319 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0085509 CG40709 - http://flybase.org/reports/FBgn0085509 protein_coding_gene - - - CG40709 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051344 CG31344 - http://flybase.org/reports/FBgn0051344 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG6572, anon-WO0118547.636, CG31344" IPR018713:Domain of unknown function DUF2236 CG31344 11-Aug-17 DroID_v2017_08 Drer\polr2gl Scer\RPB7 - Xtro\polr2g Mmus\Polr2g Hsap\POLR2G "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0051206 CG31206 - http://flybase.org/reports/FBgn0051206 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs16c12, CG31206" - CG31206 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000234 btdl buttonhead like http://flybase.org/reports/FBgn0000234 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "btd-l, btdl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,semidominant" "embryonic head,cephalopharyngeal skeleton,adult head" FBgn0039305 CG11858 - http://flybase.org/reports/FBgn0039305 protein_coding_gene isomerase activity ; GO:0016853 | inferred from electronic annotation with InterPro:IPR000297 - - "BcDNA:RH66629, CG11858" "IPR000297:Peptidyl-prolyl cis-trans isomerase, PpiC-type" CG11858 11-Aug-17 DroID_v2017_08 Drer\pin4 - Cele\pinn-4 Xtro\pin4 Mmus\Pin4 Hsap\PIN4 viable FBgn0262098 CG42851 - http://flybase.org/reports/FBgn0262098 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42851, chr2R_20696695_20697629.0" - CG42851 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037294 CG12590 - http://flybase.org/reports/FBgn0037294 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12590 "IPR032675:Leucine-rich repeat domain, L domain-like" CG12590 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010417 Taf6 TBP-associated factor 6 http://flybase.org/reports/FBgn0010417 "FBgn0011301, FBgn0016734, FBgn0052211" protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay" regulation of sequence-specific DNA binding transcription factor activity ; GO:0051090 | inferred from electronic annotation with InterPro:IPR011442 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of transcription of Notch receptor target ; GO:0007221 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:17305 inferred from sequence or structural similarity with SGD:S000003080 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:17305 inferred from sequence or structural similarity with SGD:S000003080 transcription factor TFIID complex ; GO:0005669 | inferred from physical interaction with Taf4 "dTAF[[II]]60, dmTAF6, TAF60/62, TAF, TFIID, TAF[[II]]60, taf60, TAF[[II]], Taf60, TAF6, dTAFII62, dTAF62, dTAF[[II]]62, d60, CG9348, TAF60, TAFII60, TFIID 62, TAFII60(62), TAF[[II]]60/62, Taf[[II]]60, TAF[[II]]62, dTAF[[II]]262, SR3-4B, dme-TAFII60, p62, Taf62, CG32211, Taf6, TAFII62, dTAF6, taf6, Taf-6, l(3)76BDf" "IPR004823:TATA box binding protein associated factor (TAF), IPR009072:Histone-fold, IPR011442:TAF6, C-terminal HEAT repeat domain, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG32211 11-Aug-17 DroID_v2017_08 "Drer\taf6l, Drer\taf6" Scer\TAF6 "Cele\taf-6.1, Cele\taf-6.2" "Xtro\taf6l, Xtro\taf6" "Mmus\Taf6, Mmus\Taf6l" "Hsap\TAF6, Hsap\TAF6L" "lethal - all die before end of larval stage,some die during larval stage,melanotic mass phenotype,visible,male sterile,female sterile,lethal,recessive,decreased cell number,somatic clone,germline clone,cell lethalcell lethal,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective" "melanotic mass,eye,ommatidium,eye photoreceptor cell,supernumerary,rhabdomere,wing,testis,primary spermatocyte,dorsal appendage,egg,chorion,spermatocyte,embryonic/larval brain,somatic clone,embryonic/larval neuroblast,ganglion mother cell" DRSC11299 I -1.76377163 0.324403927 -1.067379642 0.233869396 0.382784172 0.348969329 FBgn0037533 CD98hc CD98 heavy chain http://flybase.org/reports/FBgn0037533 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR013781 leucine import ; GO:0060356 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay "CG2791, cd98hc, CD98hc, RE39378p" "IPR017853:Glycoside hydrolase superfamily, IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR031984:Solute carrier family 3 member 2, N-terminal domain" CG2791 11-Aug-17 DroID_v2017_08 "Drer\zgc:158423, Drer\slc3a2a, Drer\slc3a2b, Drer\slc3a1, Drer\si:dkey-202g17.3" "Scer\IMA4, Scer\IMA2, Scer\MAL12, Scer\IMA3, Scer\IMA1, Scer\MAL32, Scer\IMA5" "Cele\atgp-1, Cele\atgp-2" "Xtro\slc3a2, Xtro\slc3a1" "Mmus\Slc3a2, Mmus\Slc3a1" "Hsap\SLC3A1, Hsap\SLC3A2" "viable,fertile" FBgn0030530 jub Ajuba LIM protein http://flybase.org/reports/FBgn0030530 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VA38 inferred from physical interaction with UniProtKB:Q9VCR6 transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN001198456 actin binding ; GO:0003779 | inferred from sequence or structural similarity with NCBI_gi:2497678 "protein localization to centrosome ; GO:0071539 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype hippo signaling ; GO:0035329 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype positive regulation of gene silencing by miRNA ; GO:2000637 | inferred from biological aspect of ancestor with PANTHER:PTN001198456 cytoskeleton organization ; GO:0007010 | inferred from biological aspect of ancestor with PANTHER:PTN001198456 positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype negative regulation of hippo signaling ; GO:0035331 | inferred from biological aspect of ancestor with PANTHER:PTN001198456 regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001198456 response to hypoxia ; GO:0001666 | inferred from biological aspect of ancestor with PANTHER:PTN001198456 positive regulation of organ growth ; GO:0046622 | inferred from mutant phenotype" apical part of cell ; GO:0045177 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay pericentriolar material ; GO:0000242 | colocalizes_with inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN001198456 cell-cell junction ; GO:0005911 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001198456 apical cortex ; GO:0045179 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN001198456 "CG11063, jub, djub, Jub" "IPR001781:Zinc finger, LIM-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG11063 11-Aug-17 DroID_v2017_08 "Drer\zyx, Drer\lpp, Drer\wtip, Drer\limd1a, Drer\trip6, Drer\fblim1, Drer\ajuba, Drer\limd1b" - Cele\zyx-1 "Xtro\pdlim5, Xtro\lpp" "Mmus\Ajuba, Mmus\Fblim1, Mmus\Lpp, Mmus\Wtip, Mmus\Zyx, Mmus\Trip6, Mmus\Limd1" "Hsap\WTIP, Hsap\FBLIM1, Hsap\TRIP6, Hsap\LPP, Hsap\AJUBA, Hsap\LIMD1, Hsap\ZYX" "lethal,viable,decreased cell growth,somatic clone,mitotic cell cycle defective,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,size defective,decreased cell number,lethal - all die before end of P-stage,some die during pharate adult stage,increased cell number,fertile,visible" "centrosome | somatic clone,spindle | somatic clone,neuroblast,somatic clone,wing,wing blade,eye | pupal stage,eye" DRSC19367 K -1.499854418 -1.119289298 -0.772691664 -0.771390149 1.437404306 1.834838305 FBgn0264896 CR44087 - http://flybase.org/reports/FBgn0264896 non_protein_coding_gene - - - CR44087 - CR44087 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062695 EP1230 EP1230 http://flybase.org/reports/FBgn0062695 gene - - - "EP(3)1230, EP1230" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000717 fo folded http://flybase.org/reports/FBgn0000717 - gene - - - fo - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,haltere,posterior scutellar bristle" FBgn0065865 l(2)SH0266 lethal (2) SH0266 http://flybase.org/reports/FBgn0065865 gene - - - "l(2)SH0266, l(2)SH2 0266" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267195 CR45635 - http://flybase.org/reports/FBgn0267195 non_protein_coding_gene - - - "CR45635, lincRNA.790" - CR45635 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053879 His4:CG33879 His4:CG33879 http://flybase.org/reports/FBgn0053879 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33879, His4:CG33879" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33879 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.19, Drer\si:ch211-113a14.6, Drer\si:ch211-113a14.26, Drer\LOC100150038, Drer\LOC794549, Drer\hist1h4l, Drer\si:dkey-23a13.7, Drer\si:dkey-108k21.28, Drer\zgc:153409, Drer\zgc:194989, Drer\LOC562770, Drer\zgc:154164, Drer\si:dkey-261m9.18, Drer\zgc:163040, Drer\si:ch73-36p18.3, Drer\LOC570405, Drer\LOC100331412, Drer\si:ch211-113a14.17, Drer\LOC100329358, Drer\si:ch73-368j24.14, Drer\si:dkey-108k21.12, Drer\si:ch73-36p18.4, Drer\si:dkey-261m9.17" "Scer\HHF1, Scer\HHF2" "Cele\his-10, Cele\his-67, Cele\his-38, Cele\his-31, Cele\his-18, Cele\his-1, Cele\his-26, Cele\his-46, Cele\his-5, Cele\his-37, Cele\his-56, Cele\his-64, Cele\his-14, Cele\his-28, Cele\his-50, Cele\his-60" "Xtro\hist1h4a, Xtro\hist1h4k, Xtro\LOC101735268, Xtro\LOC100485271, Xtro\hist1h4c, Xtro\LOC100493041" "Mmus\Hist1h4j, Mmus\Hist2h4, Mmus\Hist1h4f, Mmus\Hist4h4, Mmus\Hist1h4i, Mmus\Hist1h4n, Mmus\Hist1h4b, Mmus\Hist1h4d, Mmus\Hist1h4a, Mmus\Hist1h4c, Mmus\Hist1h4m, Mmus\Hist1h4k, Mmus\Hist1h4h" "Hsap\HIST1H4L, Hsap\HIST1H4D, Hsap\HIST1H4J, Hsap\HIST1H4B, Hsap\HIST1H4H, Hsap\HIST1H4C, Hsap\HIST2H4A, Hsap\HIST4H4, Hsap\HIST1H4A, Hsap\HIST1H4I, Hsap\HIST1H4G, Hsap\HIST1H4F, Hsap\HIST1H4E, Hsap\HIST1H4K, Hsap\HIST2H4B" FBgn0010132 l(1)tsW3 lethal (1) tsW3 http://flybase.org/reports/FBgn0010132 - gene - - - l(1)tsW3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0260093 2L3090 - http://flybase.org/reports/FBgn0260093 gene - - - 2L3090 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0062607 Mod(var)1356 Mod(var)1356 http://flybase.org/reports/FBgn0062607 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1356, Mod(var)1356" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0031945 CG7191 - http://flybase.org/reports/FBgn0031945 protein_coding_gene - - - CG7191 - CG7191 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0035931 CG13312 - http://flybase.org/reports/FBgn0035931 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG13312 IPR002557:Chitin binding domain CG13312 11-Aug-17 DroID_v2017_08 - - "Cele\W03F11.1, Cele\cbd-1" - - - viable FBgn0033381 GstE13 Glutathione S transferase E13 http://flybase.org/reports/FBgn0033381 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "BcDNA:LD22317, GstE13, gste13, CG11784, GSTE13" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG11784 11-Aug-17 DroID_v2017_08 "Drer\gstt1a, Drer\eef1e1, Drer\gstt1b, Drer\mars, Drer\gstr, Drer\gstt2, Drer\vars, Drer\eef1g" "Scer\CAM1, Scer\GTT2, Scer\URE2, Scer\YGR201C, Scer\GTT1, Scer\TEF4" - "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Eef1e1, Mmus\Gstt2, Mmus\Gstt1, Mmus\Eef1g, Mmus\Gstt3, Mmus\Gstt4, Mmus\Mars, Mmus\Vars" "Hsap\GSTT2B, Hsap\GSTT2, Hsap\GSTT1, Hsap\EEF1G, Hsap\VARS, Hsap\EEF1E1, Hsap\MARS" viable FBgn0083003 snoRNA:Psi28S-1175c snoRNA:Psi28S-1175c http://flybase.org/reports/FBgn0083003 snoRNA_gene - - - "snoRNA:Psi28S-1175c, psi28s-1175c, CR34560" - CR34560 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259246 brp bruchpilot http://flybase.org/reports/FBgn0259246 protein_coding_gene - regulation of synaptic plasticity ; GO:0048167 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from direct assay maintenance of presynaptic active zone structure ; GO:0048790 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype anesthesia-resistant memory ; GO:0007615 | inferred from direct assay cytoskeleton of presynaptic active zone ; GO:0048788 | inferred from direct assay presynaptic membrane ; GO:0042734 | colocalizes_with inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay presynaptic active zone ; GO:0048786 | "nc82, BRP, brp, Brp, NC82, CG30336, Nc82, CG42344, Cast, CG34146, CG30337, CG1931, CG12933, mAb nc82, MAbnc82, Mabnc82, CG12932, mAbnc82, bruchpilot, nc-82" IPR019323:Active zone protein ELKS CG42344 11-Aug-17 DroID_v2017_08 "Drer\erc2, Drer\erc1b, Drer\erc1a" - Cele\elks-1 "Xtro\erc1, Xtro\ccdc39, Xtro\erc2" "Mmus\Erc2, Mmus\Erc1" "Hsap\ERC1, Hsap\ERC2, Hsap\CCDC39" FBgn0053704 CG33704 - http://flybase.org/reports/FBgn0053704 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs29a11, bs30h04.y1, NEST:bs30h04, NEST:bs27f10, NEST:bs14b07, NEST:bs05b09, CG33704" - CG33704 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001513 l(1)10Fg lethal (1) 10Fg http://flybase.org/reports/FBgn0001513 - gene - - - "18, l(1)L18, l(1)10Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001956 l(2)28Bb lethal (2) 28Bb http://flybase.org/reports/FBgn0001956 - gene - - - "N, l(2)28Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083316 E(smoDN)1131 Enhancer of smoDN 1131 http://flybase.org/reports/FBgn0083316 gene - - - E(smoDN)1131 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030001 cyr cypher http://flybase.org/reports/FBgn0030001 protein_coding_gene molecular_function ; GO:0003674 | no biological data available epithelial cell morphogenesis ; GO:0003382 | inferred from sequence or structural similarity with dyl integral component of membrane ; GO:0016021 | inferred from sequence model "CG15338, cyr, CG15335" IPR001507:Zona pellucida domain CG15335 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001031, Drer\si:ch211-103f14.3, Drer\si:ch211-229d2.5, Drer\zgc:153932" - "Cele\cutl-26, Cele\cutl-20, Cele\cutl-15, Cele\cut-3, Cele\cut-6, Cele\cutl-24, Cele\cutl-9, Cele\cutl-4, Cele\cutl-6, Cele\cutl-29, Cele\cut-4, Cele\cutl-19, Cele\cutl-16, Cele\cutl-2, Cele\cutl-7, Cele\cutl-28, Cele\cutl-13, Cele\dpy-1, Cele\cutl-8, Cele\cutl-12, Cele\cut-5, Cele\cutl-25, Cele\cutl-11, Cele\cutl-10, Cele\cutl-22, Cele\cutl-1, Cele\F46G11.6, Cele\cutl-3, Cele\cutl-14, Cele\T01D1.8, Cele\ram-5, Cele\cut-1, Cele\cutl-5" "Xtro\thdl18, Xtro\MGC89178, Xtro\thdl17" - - "viable,fertile" FBgn0036897 CG8786 - http://flybase.org/reports/FBgn0036897 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR018123 ubiquitin protein ligase activity ; GO:0061630 | inferred from electronic annotation with InterPro:IPR033509 poly-ADP-D-ribose binding ; GO:0072572 | inferred from sequence or structural similarity with HGNC:21336 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:21336" Wnt signaling pathway ; GO:0016055 | inferred from electronic annotation with InterPro:IPR033509 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:21336 protein destabilization ; GO:0031648 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:21336 "BcDNA:GM01527, CG8786, RNF146, DRNF146" "IPR018123:WWE domain, subgroup, IPR001841:Zinc finger, RING-type, IPR004170:WWE domain, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033509:E3 ubiquitin-protein ligase RNF146" CG8786 11-Aug-17 DroID_v2017_08 "Drer\rnf146, Drer\pex2" - "Cele\C02B8.6, Cele\Y105E8A.14, Cele\C32D5.10, Cele\C55A6.12, Cele\C26B9.6, Cele\C55A6.1" Xtro\rnf146 Mmus\Rnf146 Hsap\RNF146 "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0024973 CG2701 - http://flybase.org/reports/FBgn0024973 FBgn0020598 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-3Bd, EG:95B7.9, II, CG2701" "IPR003892:Ubiquitin system component Cue, IPR009060:UBA-like" CG2701 11-Aug-17 DroID_v2017_08 Drer\ascc2 Scer\CUE3 Cele\fbxa-37 Xtro\ascc2 Mmus\Ascc2 Hsap\ASCC2 viable FBgn0013598 l(3)B3-3-21 lethal (3) B3-3-21 http://flybase.org/reports/FBgn0013598 - gene - - - l(3)B3-3-21 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260269 GSd217 - http://flybase.org/reports/FBgn0260269 gene - - - GSd217 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective" FBgn0261638 CR42721 - http://flybase.org/reports/FBgn0261638 non_protein_coding_gene - - - CR42721 - CR42721 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085554 CG41015 - http://flybase.org/reports/FBgn0085554 protein_coding_gene - - - CG41015 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003408 Sil Skilike http://flybase.org/reports/FBgn0003408 - gene - - - Sil - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority live,visible,semidominant" wing FBgn0065516 l(2)SH1142 lethal (2) SH1142 http://flybase.org/reports/FBgn0065516 gene - - - "l(2)SH1142, l(2)SH2 1142" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031461 daw dawdle http://flybase.org/reports/FBgn0031461 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR001111, InterPro:IPR001839, InterPro:IPR017948 cytokine activity ; GO:0005125 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 transforming growth factor beta receptor binding ; GO:0005160 | inferred from biological aspect of ancestor with PANTHER:PTN000218063" activin receptor signaling pathway ; GO:0032924 | inferred from direct assay transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype positive regulation of pathway-restricted SMAD protein phosphorylation ; GO:0010862 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 positive regulation of activin receptor signaling pathway ; GO:0032927 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of MAPK cascade ; GO:0043408 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype regulation of insulin secretion ; GO:0050796 | inferred from mutant phenotype SMAD protein signal transduction ; GO:0060395 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 "daw, CG16987, Alp23b, Alp, ALP23B, Alp23B, DAW, cg16987, Daw" "IPR001111:TGF-beta, propeptide, IPR001839:Transforming growth factor-beta, C-terminal, IPR015615:Transforming growth factor-beta-related, IPR017948:Transforming growth factor beta, conserved site, IPR029034:Cystine-knot cytokine" CG16987 11-Aug-17 DroID_v2017_08 "Drer\gdf6a, Drer\gdf5, Drer\bmp7a, Drer\bmp10l, Drer\gdf11, Drer\inhbb, Drer\gdf10b, Drer\bmp8a, Drer\bmp2b, Drer\bmp2a, Drer\inha, Drer\inhbab, Drer\lft1, Drer\tgfb3, Drer\bmp3, Drer\gdf9, Drer\ndr1, Drer\tgfb1a, Drer\gdf7, Drer\LOC100332902, Drer\amh, Drer\lft2, Drer\LOC100329520, Drer\tgfb1b, Drer\gdf6b, Drer\gdf3, Drer\gdf10a, Drer\bmp15, Drer\gdf2, Drer\spaw, Drer\bmp6, Drer\tgfb2, Drer\admp, Drer\mstnb, Drer\ndr2, Drer\mstna, Drer\tgfb2l, Drer\bmp10, Drer\bmp4, Drer\bmp7b, Drer\inhbaa" "Scer\DIA2, Scer\MCM3" "Cele\dbl-1, Cele\tig-3, Cele\emb-30, Cele\daf-7" "Xtro\inha, Xtro\bmp2, Xtro\tgfb1, Xtro\nodal, Xtro\nodal5, Xtro\inhba, Xtro\bmp15, Xtro\lefty, Xtro\bmp6, Xtro\gdf2, Xtro\tgfb2, Xtro\bmp3, Xtro\bmp7.1, Xtro\gdf7, Xtro\bmp4, Xtro\gdf9, Xtro\admp, Xtro\gdf3, Xtro\bmp8, Xtro\nodal6, Xtro\nodal1, Xtro\bmp5, Xtro\mstn.1, Xtro\inhbc.1, Xtro\gdf1, Xtro\bmp7.2, Xtro\gdf5, Xtro\nodal, Xtro\gdf10, Xtro\gdf11.1, Xtro\bmp10" "Mmus\Gdf9, Mmus\Gdf2, Mmus\Gdf1, Mmus\Gdf15, Mmus\Lefty2, Mmus\Bmp15, Mmus\Gdf11, Mmus\Bmp7, Mmus\Nodal, Mmus\Bmp4, Mmus\Inhbe, Mmus\Gdf3, Mmus\Lefty1, Mmus\Tgfb1, Mmus\Gdf7, Mmus\Bmp10, Mmus\Inhba, Mmus\Bmp3, Mmus\Gdf5, Mmus\Bmp2, Mmus\Bmp5, Mmus\Gdf10, Mmus\Mcm3, Mmus\Gdf6, Mmus\Inhbb, Mmus\Bmp8b, Mmus\Tgfb3, Mmus\Mstn, Mmus\Tgfb2, Mmus\Amh, Mmus\Inha, Mmus\Bmp8a, Mmus\Bmp6, Mmus\Inhbc" "Hsap\LEFTY2, Hsap\BMP3, Hsap\BMP10, Hsap\GDF3, Hsap\BMP8A, Hsap\INHBA, Hsap\GDF6, Hsap\NODAL, Hsap\GDF1, Hsap\GDF15, Hsap\BMP15, Hsap\TGFB3, Hsap\TGFB2, Hsap\TGFB1, Hsap\LEFTY1, Hsap\INHBE, Hsap\MSTN, Hsap\BMP5, Hsap\GDF7, Hsap\GDF10, Hsap\BMP4, Hsap\GDF9, Hsap\GDF11, Hsap\GDF2, Hsap\INHA, Hsap\GDF5, Hsap\INHBC, Hsap\BMP2, Hsap\INHBB, Hsap\BMP6, Hsap\AMH, Hsap\BMP7, Hsap\BMP8B" "neuroanatomy defective,hypoactive,uncoordinated,lethal - all die before end of pupal stage,some die during pupal stage,partially,partially lethal - majority die,some die during larval stage,long lived,flight defective,progressive,RU486 conditional,viable,melanotic mass phenotype,circadian rhythm defective,heat sensitive" "intersegmental nerve,abdominal segmental nerve,intersegmental nerve branch ISNb of A1-7,embryonic/larval optic lobe,axon & eye photoreceptor cell,embryonic/larval anal pad,adult somatic muscle,progressive,lysosome | progressiveMhc.PW,autophagic vacuoleMhc.PW,melanotic mass,leg,bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" DRSC00479 I -0.422886708 1.586324583 -0.497186904 0.011384592 -0.488070278 -0.522160377 FBgn0267984 CR46251 - http://flybase.org/reports/FBgn0267984 non_protein_coding_gene - - - CR46251 - CR46251 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034999 CG3394 - http://flybase.org/reports/FBgn0034999 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG3394 "IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site, IPR025110:AMP-binding enzyme C-terminal domain" CG3394 11-Aug-17 DroID_v2017_08 "Drer\slc27a1a, Drer\slc27a4, Drer\LOC568883, Drer\slc27a6, Drer\slc27a1b, Drer\zgc:158482, Drer\slc27a2b, Drer\slc27a2a" Scer\FAT1 "Cele\acs-20, Cele\acs-22" "Xtro\slc27a2, Xtro\slc27a3, Xtro\slc27a6" "Mmus\Slc27a5, Mmus\Slc27a2, Mmus\Slc27a6, Mmus\Slc27a4, Mmus\Slc27a3, Mmus\Slc27a1" "Hsap\SLC27A3, Hsap\SLC27A6, Hsap\SLC27A5, Hsap\SLC27A2, Hsap\SLC27A4, Hsap\SLC27A1" viable DRSC04366 K 0.036404441 -0.475948389 -0.213946908 0.463946247 0.380184075 1.919134013 FBgn0243501 l(2)CB05177 - http://flybase.org/reports/FBgn0243501 gene - - - l(2)CB05177 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0263963 BG01878 - http://flybase.org/reports/FBgn0263963 gene - - - BG01878 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,female limited,starvation stress response defective,gravitaxis defective,male limited" FBgn0038551 Odj Oddjob http://flybase.org/reports/FBgn0038551 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 heterochromatin ; GO:0000792 | inferred from direct assay "Odj, CG7357" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG7357 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-241b2.4, Drer\znf408" "Scer\AZF1, Scer\MET32" "Cele\Y55F3AM.14, Cele\klf-3, Cele\lin-29, Cele\lst-5, Cele\ztf-23, Cele\M03D4.4" Xtro\hic1 "Mmus\Zfp810, Mmus\Rbak, Mmus\Zfp518b" "Hsap\ZNF518B, Hsap\ZNF8, Hsap\ZNF560, Hsap\ZNF281, Hsap\GFI1B" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0052865 alphagamma-element:CR32865 alphagamma-element:CR32865 http://flybase.org/reports/FBgn0052865 non_protein_coding_gene - - - "CR32865, alphagamma-element:CR32865" - CR32865 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266451 fau fau http://flybase.org/reports/FBgn0266451 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to anoxia ; GO:0034059 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG45077, Fau, CG6544, BcDNA:HL07933, fau" - CG45077 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010876 l(3)05820 lethal (3) 05820 http://flybase.org/reports/FBgn0010876 - gene - - - l(3)05820 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002093 l(2)57Bc lethal (2) 57Bc http://flybase.org/reports/FBgn0002093 - gene - - - l(2)57Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259631 B0611 - http://flybase.org/reports/FBgn0259631 gene - - - B0611 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,tarsal segment,unguis,leg,arista" FBgn0001741 l(1)HM11 lethal (1) HM11 http://flybase.org/reports/FBgn0001741 - gene - - - l(1)HM11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0025486 l(3)82Eb lethal (3) 82Eb http://flybase.org/reports/FBgn0025486 - gene - - - l(3)82Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" FBgn0051836 CG31836 - http://flybase.org/reports/FBgn0051836 protein_coding_gene - - - CG31836 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267919 CR46200 - http://flybase.org/reports/FBgn0267919 non_protein_coding_gene - - - "CR46200, lincRNA.412" - CR46200 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065659 l(2)SH0715 lethal (2) SH0715 http://flybase.org/reports/FBgn0065659 gene - - - "l(2)SH0715, l(2)SH2 0715" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040262 Ugt36Ba Ugt36Ba http://flybase.org/reports/FBgn0040262 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG13270, AC 005121A, Ugt36Ba" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG13270 11-Aug-17 DroID_v2017_08 "Drer\ugt5c3, Drer\ugt5a2, Drer\ugt2a6, Drer\ugt5a4, Drer\ugt1b2, Drer\ugt1b7, Drer\ugt5c1, Drer\ugt5b2, Drer\ugt1ab, Drer\ugt5f1, Drer\ugt2b5, Drer\ugt2a5, Drer\ugt1b3, Drer\ugt2b6, Drer\ugt5g2, Drer\ugt5d1, Drer\ugt2a2, Drer\ugt8, Drer\ugt5e1, Drer\ugt1b5, Drer\zgc:172315, Drer\ugt5g1, Drer\ugt5c2, Drer\ugt5a1, Drer\ugt5b1, Drer\ugt5a5, Drer\ugt1b4, Drer\ugt5b6, Drer\ugt2b1, Drer\ugt2b3, Drer\ugt5b3" Scer\ATG26 "Cele\ugt-35, Cele\ugt-49, Cele\ugt-44, Cele\C03A7.13, Cele\ugt-39, Cele\ugt-10, Cele\ugt-57, Cele\C23G10.6, Cele\ugt-60, Cele\ugt-16, Cele\ugt-52, Cele\ugt-56, Cele\ugt-2, Cele\ugt-61, Cele\ugt-55, Cele\ugt-54, Cele\ugt-34, Cele\ugt-3, Cele\ugt-24, Cele\ugt-29, Cele\ugt-19, Cele\ugt-23, Cele\ugt-18, Cele\ugt-32, Cele\ugt-45, Cele\ugt-53, Cele\ugt-48, Cele\ugt-4, Cele\ugt-31, Cele\ugt-47, Cele\ugt-50, Cele\ugt-8, Cele\H23N18.4, Cele\ugt-27, Cele\ugt-13, Cele\ugt-6, Cele\ugt-37, Cele\ugt-51, Cele\ugt-1, Cele\ugt-43, Cele\ugt-7, Cele\ugt-40, Cele\Y43D4A.2, Cele\ugt-28, Cele\ugt-12, Cele\ugt-25, Cele\C55H1.1, Cele\ugt-26, Cele\ugt-42, Cele\ugt-5, Cele\ugt-15, Cele\ugt-22, Cele\ugt-21, Cele\C03A7.12, Cele\ugt-46, Cele\ugt-11, Cele\ugt-38, Cele\ugt-41, Cele\F54C1.1, Cele\ugt-17, Cele\ugt-20, Cele\ugt-59, Cele\F10D2.8, Cele\ugt-62, Cele\ugt-30, Cele\ugt-36, Cele\K04A8.10, Cele\ugt-33, Cele\ugt-58, Cele\ugt-14, Cele\ugt-9" "Xtro\ugt3a2, Xtro\ugt1a6, Xtro\ugt2a1, Xtro\ugt2b4, Xtro\ugt8" "Mmus\Ugt2b37, Mmus\Ugt8a, Mmus\Ugt1a5, Mmus\Ugt3a2, Mmus\Ugt1a2, Mmus\Ugt1a6b, Mmus\Ugt3a1, Mmus\Ugt2b34, Mmus\Ugt1a9, Mmus\Ugt2a3, Mmus\Ugt2b38, Mmus\Ugt2b5, Mmus\Ugt1a1, Mmus\Ugt2b1, Mmus\Ugt2b36, Mmus\Ugt1a7c, Mmus\Ugt2a1, Mmus\Ugt2b35, Mmus\Ugt1a6a" "Hsap\UGT1A1, Hsap\UGT1A9, Hsap\UGT1A4, Hsap\UGT1A8, Hsap\UGT3A2, Hsap\UGT2B4, Hsap\UGT3A1, Hsap\UGT2B10, Hsap\UGT2B15, Hsap\UGT8, Hsap\UGT2A3, Hsap\UGT2B28, Hsap\UGT2A2, Hsap\UGT2B17, Hsap\UGT1A5, Hsap\UGT1A6, Hsap\UGT1A10, Hsap\UGT2B11, Hsap\UGT2B7, Hsap\UGT1A3, Hsap\UGT1A7" viable FBgn0259303 C488 - http://flybase.org/reports/FBgn0259303 gene - - - C488 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing vein,chaeta,ectopic" FBgn0032654 CG15147 - http://flybase.org/reports/FBgn0032654 protein_coding_gene - - - CG15147 - CG15147 11-Aug-17 DroID_v2017_08 Drer\cenpa - - - Mmus\Selenoh Hsap\SELENOH viable FBgn0069210 kek1::kek2 kek1::kek2 http://flybase.org/reports/FBgn0069210 engineered_fusion_gene - - - kek1::kek2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,visible" "chorion,eye,ommatidium" FBgn0038391 GATAe GATAe http://flybase.org/reports/FBgn0038391 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088 RNA polymerase II transcription factor binding ; GO:0001085 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with MGI:MGI:107516 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001228 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000801139" endoderm development ; GO:0007492 | inferred from mutant phenotype intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype enterocyte differentiation ; GO:1903703 | inferred from mutant phenotype enteroendocrine cell differentiation ; GO:0035883 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 nucleus ; GO:0005634 | inferred from direct assay "dGATAe, dGATA-E, CG10278, GATAe, CG10278-PA" "IPR000679:Zinc finger, GATA-type, IPR013088:Zinc finger, NHR/GATA-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical" CG10278 11-Aug-17 DroID_v2017_08 "Drer\trps1, Drer\gata2b, Drer\gata1a, Drer\gata3, Drer\gata4, Drer\zglp1, Drer\gata5, Drer\gata2a, Drer\gata1b, Drer\gata6" "Scer\GAT4, Scer\SRD1, Scer\DAL80, Scer\GZF3, Scer\GAT1, Scer\ECM23, Scer\GAT3, Scer\GLN3, Scer\GAT2" "Cele\elt-4, Cele\med-2, Cele\elt-7, Cele\elt-2, Cele\elt-3, Cele\end-1, Cele\end-3, Cele\med-1, Cele\elt-1, Cele\egl-18, Cele\elt-6" "Xtro\trps1, Xtro\gata1, Xtro\gata2, Xtro\gata3, Xtro\gata4, Xtro\gata6, Xtro\gata5" "Mmus\Gata6, Mmus\Gata2, Mmus\Gata4, Mmus\Gata5, Mmus\Gata3, Mmus\Gata1, Mmus\Zglp1, Mmus\Trps1" "Hsap\GATA2, Hsap\ZGLP1, Hsap\GATA5, Hsap\GATA1, Hsap\GATA4, Hsap\GATA3, Hsap\GATA6, Hsap\TRPS1" "viable,visible" mesothoracic tergum FBgn0040279 Osi14 Osiris 14 http://flybase.org/reports/FBgn0040279 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Sp558, CG1155, SP558, BEST:LD24139, Osi14, osi14" IPR012464:Protein of unknown function DUF1676 CG1155 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283450 Glo1 Glyoxalase 1 http://flybase.org/reports/FBgn0283450 protein_coding_gene "lactoylglutathione lyase activity ; GO:0004462 | inferred from electronic annotation with InterPro:IPR004361, InterPro:IPR018146 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR004361, InterPro:IPR018146" - - "glo1, Glo1, CG1707" "IPR004360:Glyoxalase/fosfomycin resistance/dioxygenase domain, IPR004361:Glyoxalase I, IPR018146:Glyoxalase I, conserved site, IPR029068:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase" CG1707 11-Aug-17 DroID_v2017_08 Drer\glo1 Scer\GLO1 - Xtro\glo1 Mmus\Glo1 Hsap\GLO1 "viable,visible" trichogen cell FBgn0019894 anon-2Bc anon-2Bc http://flybase.org/reports/FBgn0019894 - gene - - - anon-2Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017624 Eig76Ea Eig76Ea http://flybase.org/reports/FBgn0017624 - gene - - - "Eig76-1, Eig76Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000477 DNaseII Deoxyribonuclease II http://flybase.org/reports/FBgn0000477 FBgn0038563 protein_coding_gene deoxyribonuclease II activity ; GO:0004531 | inferred from electronic annotation with InterPro:IPR004947 deoxyribonuclease II activity ; GO:0004531 | traceable author statement deoxyribonuclease II activity ; GO:0004531 | non-traceable author statement endodeoxyribonuclease activity ; GO:0004520 | inferred from sequence or structural similarity with MGI:MGI:1913283 nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000092274 DNA catabolic process ; GO:0006308 | traceable author statement intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000092274 "DNase, CG7780, DNase-1, dDNase II, DNase 1, DNase1, DNaseII, dnaseII, dnaseII[lo]" IPR004947:Deoxyribonuclease II CG7780 11-Aug-17 DroID_v2017_08 "Drer\dnase2b, Drer\dnase2" - "Cele\crn-7, Cele\crn-6, Cele\nuc-1" "Xtro\dnase2, Xtro\dnase2b" "Mmus\Dnase2a, Mmus\Dnase2b" "Hsap\DNASE2B, Hsap\DNASE2" "electrophoretic variant,viable,cell death defective,semi-fertile,increased cell death,conditional,germline clone" "ovary,egg chamber,conditional,nurse cell,nucleus | oogenesis stage S14,germline clone,nucleus | germline clone | oogenesis stage S14" FBgn0001628 l(1)dn5 lethal (1) discs normal 5 http://flybase.org/reports/FBgn0001628 - gene - - - "l(1)d.norm.-5, l(1)dn5" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0041591 l(3)S052908a lethal (3) S052908a http://flybase.org/reports/FBgn0041591 gene - - - "l(3)S052908, 529.08, 0529/08, l(3)S052908a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" presumptive embryonic/larval nervous system FBgn0060652 l(3)S083311 lethal (3) S083311 http://flybase.org/reports/FBgn0060652 gene - - - "0833/11, l(3)S083311" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0015983 l(2)PC4-K lethal (2) PC4-K http://flybase.org/reports/FBgn0015983 - gene - - - "l(2)PC4-L, l(2)PC4-K" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262168 ind::Drer\gsx1 - http://flybase.org/reports/FBgn0262168 engineered_fusion_gene - - - "Gind, IndGsh1, ind::Brer\gsx1, ind::Drer\gsx1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069193 l(3)DJ688 lethal (3) DJ688 http://flybase.org/reports/FBgn0069193 gene - - - l(3)DJ688 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001040 fs(3)H172 female sterile (3) H172 http://flybase.org/reports/FBgn0001040 - gene - - - fs(3)H172 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile oocyte FBgn0038034 Cyp9f3Psi Cyp9f3Psi http://flybase.org/reports/FBgn0038034 pseudogene_attribute - - - "Cyp9f3, 9f3p, Cyp9f3p, CG17875, CR17875, Cyp9f3Psi" - CR17875 11-Aug-17 DroID_v2017_08 - - - - - - DRSC25711 K -0.165384357 0.138898596 -0.537593954 0.112713843 -0.68411392 -1.577435914 FBgn0000857 fs(1)M51 female sterile (1) M51 http://flybase.org/reports/FBgn0000857 - gene - - - fs(1)M51 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile chorion FBgn0085718 CG41600 - http://flybase.org/reports/FBgn0085718 protein_coding_gene - - - CG41600 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260262 GSd449 - http://flybase.org/reports/FBgn0260262 gene - - - GSd449 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030432 CG4404 - http://flybase.org/reports/FBgn0030432 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - - CG4404 "IPR004210:BESS motif, IPR006578:MADF domain" CG4404 11-Aug-17 DroID_v2017_08 "Drer\LOC100330838, Drer\si:ch211-207i20.3, Drer\zgc:152938" - "Cele\madf-9, Cele\madf-2, Cele\madf-4, Cele\madf-8, Cele\madf-3, Cele\madf-10, Cele\madf-5" - - - "lethal,partially lethal - majority die,visible" "chaeta,supernumerary,trichogen cell" FBgn0030039 CG12123 - http://flybase.org/reports/FBgn0030039 protein_coding_gene - - - CG12123 IPR032072:Protein of unknown function DUF4807 CG12123 11-Aug-17 DroID_v2017_08 - - Cele\F58A4.6 - - - "viable,fertile,body color defective" mesothoracic tergum DRSC17818 K 0.406728332 0.042875329 -0.324007984 -0.664236012 0.415530341 4.381010251 FBgn0259334 C935 - http://flybase.org/reports/FBgn0259334 gene - - - C935 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing hair FBgn0037750 Whamy WHAMM and JMY related http://flybase.org/reports/FBgn0037750 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR003124 GTPase binding ; GO:0051020 | inferred from physical interaction with Cdc42 Rac GTPase binding ; GO:0048365 | inferred from physical interaction with Rac1 cell migration ; GO:0016477 | inferred from mutant phenotype positive regulation of actin nucleation ; GO:0051127 | inferred from direct assay microtubule bundle formation ; GO:0001578 | inferred from direct assay myoblast fusion ; GO:0007520 | inferred from genetic interaction with WASp positive regulation of actin filament polymerization ; GO:0030838 | inferred from direct assay mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay lamellipodium ; GO:0030027 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Whamy, CG12946" "IPR003124:WH2 domain, IPR000095:CRIB domain" CG12946 11-Aug-17 DroID_v2017_08 "Drer\wasb, Drer\wasla, Drer\waslb, Drer\wasa, Drer\si:dkey-197j19.6" Scer\LAS17 "Cele\B0280.13, Cele\T24B8.4, Cele\C31C9.6, Cele\wsp-1, Cele\B0280.2" "Xtro\wasl, Xtro\was" "Mmus\Wasl, Mmus\Was" "Hsap\WAS, Hsap\WASL" "viable,fertile" FBgn0261064 Rbsn-5 Rabenosyn-5 http://flybase.org/reports/FBgn0261064 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306, InterPro:IPR007087 small GTPase binding ; GO:0031267 | inferred from physical interaction with Rab5 protein binding ; GO:0005515 | inferred from physical interaction with Vps45 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN001004537" plasma membrane to endosome transport ; GO:0048227 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype Golgi to vacuole transport ; GO:0006896 | inferred from biological aspect of ancestor with PANTHER:PTN001004537 oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype vacuole inheritance ; GO:0000011 | inferred from biological aspect of ancestor with PANTHER:PTN001004537 Golgi to endosome transport ; GO:0006895 | inferred from biological aspect of ancestor with PANTHER:PTN001004537 endosomal vesicle fusion ; GO:0034058 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype cytoplasmic side of endosome membrane ; GO:0010009 | inferred from biological aspect of ancestor with PANTHER:PTN001004537 endosome ; GO:0005768 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay "CG8506, rbsn, rbsn-5, EEA1, MENE(2L)-C, MENE (2L)-C, Rbsn-5, Rbsn, Rbsn5" "IPR000306:FYVE zinc finger, IPR011011:Zinc finger, FYVE/PHD-type, IPR017455:Zinc finger, FYVE-related, IPR013087:Zinc finger C2H2-type, IPR021565:Rabenosyn, Rab binding domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8506 11-Aug-17 DroID_v2017_08 Drer\rbsn Scer\PEP7 Cele\rabs-5 Xtro\rbsn Mmus\Rbsn Hsap\RBSN FBgn0011614 l(1)I33f18 lethal (1) I33f18 http://flybase.org/reports/FBgn0011614 FBgn0010206 gene - - - "l(1)33f18, l(1)I33f18" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034720 Liprin-gamma Liprin-gamma http://flybase.org/reports/FBgn0034720 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Lar inferred from physical interaction with Liprin-α protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Liprin-γ negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from genetic interaction with Liprin-β axon target recognition ; GO:0007412 | inferred from genetic interaction with Liprin-α protein complex ; GO:0043234 | inferred from direct assay "Liprin CG11206, Liprin-gamma, CG11206, liprin gamma" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG11206 11-Aug-17 DroID_v2017_08 "Drer\ppfia3, Drer\ppfia2, Drer\ppfibp1b, Drer\ppfibp1a, Drer\kaznb, Drer\ppfia4, Drer\kazna" - Cele\syd-2 "Xtro\ppfibp2, Xtro\ppfia3, Xtro\ppfibp1, Xtro\ppfia1, Xtro\kazn" "Mmus\Ppfibp1, Mmus\Ppfia2, Mmus\Ppfia1, Mmus\Ppfia3, Mmus\Kazn, Mmus\Ppfia4, Mmus\Ppfibp2" "Hsap\KAZN, Hsap\PPFIA1, Hsap\PPFIBP1, Hsap\PPFIA4, Hsap\PPFIA2, Hsap\PPFIA3, Hsap\PPFIBP2" "viable,fertile" FBgn0261604 M(3)80F Minute (3) 80F http://flybase.org/reports/FBgn0261604 gene - - - M(3)80F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029081 iab-7PRE iab-7 Polycomb group response element http://flybase.org/reports/FBgn0029081 regulatory_region - gene silencing ; GO:0016458 | inferred from direct assay - "iab-7-PRE, iab, Fab7 PRE, iab-7PRE, Fab7, iab-7 PRE, iab-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye FBgn0260111 2L2084 - http://flybase.org/reports/FBgn0260111 gene - - - 2L2084 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0032346 Csl4 Csl4 http://flybase.org/reports/FBgn0032346 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR019495 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype transcriptionally active chromatin ; GO:0035327 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000005176 inferred from direct assay exosome (RNase complex) ; GO:0000178 | inferred from direct assay "CSL4, CG6249, dCsl4, Csl4" "IPR025721:Exosome complex component, N-terminal domain, IPR012340:Nucleic acid-binding, OB-fold, IPR019495:Exosome complex component CSL4" CG6249 11-Aug-17 DroID_v2017_08 Drer\exosc1 Scer\CSL4 Cele\exos-1 Xtro\exosc1 Mmus\Exosc1 Hsap\EXOSC1 "visible,partially lethal - majority die,some die during pupal stage,female sterile" mesothoracic tergum FBgn0024665 l(2)k05636 lethal (2) k05636 http://flybase.org/reports/FBgn0024665 - gene - - - "56/36, l(2)k05636" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034372 Gint3 GDI interacting protein 3 http://flybase.org/reports/FBgn0034372 protein_coding_gene - - - "CG5469, Gint3, Dromel_CG5469_FBtr0086654_gint3_mORF, UBX 6 like" "IPR001012:UBX domain, IPR018997:PUB domain, IPR029071:Ubiquitin-related domain" CG5469 11-Aug-17 DroID_v2017_08 Drer\ubxn6 Scer\UBX4 "Cele\ubxn-6, Cele\B0024.10" "Xtro\ubxn6, Xtro\aspscr1" "Mmus\Ubxn6, Mmus\Aspscr1" "Hsap\UBXN6, Hsap\ASPSCR1" DRSC06934 K 0.361206605 -0.200481122 0.512960516 -1.012811105 -1.61677704 -0.484780597 FBgn0265949 CR44736 - http://flybase.org/reports/FBgn0265949 non_protein_coding_gene - - - CR44736 - CR44736 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260120 2L2853 - http://flybase.org/reports/FBgn0260120 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2853 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "terminal tracheal cell,somatic clone,dorsal air sac primordium,embryonic/larval tracheal system" FBgn0035267 CG13921 - http://flybase.org/reports/FBgn0035267 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13921 - CG13921 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033244 CG8726 - http://flybase.org/reports/FBgn0033244 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR003124 phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein phosphorylation ; GO:0006468 | NOT inferred from key residues - CG8726 "IPR000719:Protein kinase domain, IPR001683:Phox homologous domain, IPR003124:WH2 domain, IPR011009:Protein kinase-like domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG8726 11-Aug-17 DroID_v2017_08 "Drer\pxk, Drer\sgk3" - - Xtro\pxk "Mmus\Sgk3, Mmus\Pxk" "Hsap\PXK, Hsap\C8orf44-SGK3" viable FBgn0004683 Ifm(2)11 Indirect flight muscle (2) 11 http://flybase.org/reports/FBgn0004683 - gene - - - Ifm(2)11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "flight defective,dominant" "wing,myofibril,A band" FBgn0038576 Arp5 Actin-related protein 5 http://flybase.org/reports/FBgn0038576 protein_coding_gene ATP-dependent 3'-5' DNA helicase activity ; GO:0043140 | contributes_to inferred from sequence or structural similarity with SGD:S000005004 "chromatin remodeling ; GO:0006338 | inferred from sequence or structural similarity with SGD:S000005004 regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay Ino80 complex ; GO:0031011 | inferred from direct assay "Arp5, CG7940, dArp5" IPR004000:Actin family CG7940 11-Aug-17 DroID_v2017_08 Drer\actr5 Scer\ARP5 - Xtro\actr5 Mmus\Actr5 Hsap\ACTR5 viable FBgn0040309 Jafrac1 thioredoxin peroxidase 1 http://flybase.org/reports/FBgn0040309 protein_coding_gene thioredoxin peroxidase activity ; GO:0008379 | inferred from direct assay thioredoxin peroxidase activity ; GO:0008379 | non-traceable author statement "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 germ cell migration ; GO:0008354 | inferred from mutant phenotype cell redox homeostasis ; GO:0045454 | inferred from direct assay response to starvation ; GO:0042594 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype hydrogen peroxide catabolic process ; GO:0042744 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "jafrac1, CG1633, T20, DmTPx-1, DPx-4783, DPx4783, SSP5111, Prx4783, Jafrac1, Jafrac, dPrx I, jf1, cTPx, Prx, 1633, Dpx-4783, PRDX1_DROME, JAFRAC 1" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR024706:Peroxiredoxin, AhpC-type, IPR013766:Thioredoxin domain" CG1633 11-Aug-17 DroID_v2017_08 "Drer\prdx1, Drer\prdx3, Drer\prdx2, Drer\prdx4, Drer\prdx6" "Scer\PRX1, Scer\TSA2, Scer\TSA1" "Cele\prdx-3, Cele\prdx-2, Cele\prdx-6" "Xtro\prdx1, Xtro\prdx2, Xtro\prdx4, Xtro\prdx3" "Mmus\Prdx6, Mmus\Prdx1, Mmus\Prdx2, Mmus\Prdx4, Mmus\Prdx3" "Hsap\PRDX3, Hsap\PRDX1, Hsap\PRDX2, Hsap\PRDX6, Hsap\PRDX4" "cell migration defective,cell adhesion defective,oxidative stress response defective,starvation stress response defective,long lived,RU486 conditional,short lived,conditional" "germline cell,maternal effect" FBgn0061153 l(2)I46 lethal (2) I46 http://flybase.org/reports/FBgn0061153 gene - - - "M237, I46, l(2)I46" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037765 CG9458 - http://flybase.org/reports/FBgn0037765 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "CG9458, CT26802" "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG9458 11-Aug-17 DroID_v2017_08 "Drer\elovl4a, Drer\elovl5, Drer\elovl8a, Drer\elovl7a, Drer\elovl8b, Drer\elovl2, Drer\elovl1a, Drer\elovl1b, Drer\elovl4b, Drer\elovl7b" "Scer\ELO1, Scer\ELO3, Scer\ELO2" "Cele\elo-5, Cele\elo-4, Cele\elo-3" "Xtro\elovl5, Xtro\elovl1, Xtro\elovl7, Xtro\elovl2" "Mmus\Elovl2, Mmus\Elovl7, Mmus\Elovl5, Mmus\Elovl1, Mmus\Elovl4, Mmus\Elovl6" "Hsap\ELOVL7, Hsap\ELOVL2, Hsap\ELOVL1, Hsap\ELOVL6, Hsap\ELOVL4, Hsap\ELOVL5" DRSC16495 I 0.66562253 1.785600847 0.526945437 -0.565277997 0.344965777 -0.250933127 FBgn0026262 bip2 bip2 http://flybase.org/reports/FBgn0026262 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 POZ domain binding ; GO:0031208 | inferred from physical interaction with bab1 inferred from physical interaction with bab2 chromatin binding ; GO:0003682 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf10 p53 binding ; GO:0002039 | inferred from physical interaction with p53 transcription factor binding ; GO:0008134 | inferred from physical interaction with Trl transcription factor binding ; GO:0008134 | inferred from physical interaction with bab1 inferred from physical interaction with bab2 protein binding ; GO:0005515 | inferred from physical interaction with bab1 inferred from physical interaction with bab2 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype inferred from genetic interaction with Trl nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from direct assay "i31, i163, CG2009, TFIID, dTAF[[II]]155, dBIP2, TAF[[II]]155, TAF3, BIP2, TAFII155, bip-II, bip2, Bip2, TAF155, dTAFII3, DmTAF3, dmTAF3" "IPR001965:Zinc finger, PHD-type, IPR006565:Bromodomain associated domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2009 11-Aug-17 DroID_v2017_08 "Drer\ing5b, Drer\ing1, Drer\taf8, Drer\ing3, Drer\taf3, Drer\ing5a, Drer\ing2, Drer\ing4" "Scer\PHO23, Scer\YNG1, Scer\TAF3, Scer\YNG2" "Cele\Y54E2A.8, Cele\taf-3, Cele\phf-34, Cele\taf-8" "Xtro\ing3, Xtro\taf3, Xtro\taf8, Xtro\ing1, Xtro\ing5, Xtro\ing2" "Mmus\Ing2, Mmus\Ing5, Mmus\Taf3, Mmus\Ing4, Mmus\Ing3, Mmus\Taf8, Mmus\Ing1" "Hsap\ING4, Hsap\TAF8, Hsap\ING2, Hsap\ING3, Hsap\ING1, Hsap\ING5, Hsap\TAF3" "lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable" DRSC17170 E -1.459721975 1.369222901 -1.563311271 0.625598761 1.014788422 1.085034966 FBgn0027991 l(3)S126801 lethal (3) S126801 http://flybase.org/reports/FBgn0027991 gene - - - "1268/01, l(3)S126801" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069119 ms(3)Z4934 ms(3)Z4934 http://flybase.org/reports/FBgn0069119 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(3)Z4934 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "onion stage spermatid,Nebenkern derivative,onion stage spermatid & nucleus" FBgn0265649 CR44456 - http://flybase.org/reports/FBgn0265649 non_protein_coding_gene - - - CR44456 - CR44456 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0284444 ddbt deadbeat http://flybase.org/reports/FBgn0284444 protein_coding_gene molecular_function ; GO:0003674 | no biological data available telomere capping ; GO:0016233 | inferred from mutant phenotype "nuclear chromosome, telomeric region ; GO:0000784 | inferred from direct assay" "ddbt, CG34264, HDC07730" - CG34264 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267880 CR46168 - http://flybase.org/reports/FBgn0267880 pseudogene_attribute - - - "CR46168, CG12717-related" - CR46168 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023036 l(2)46Eg lethal (2) 46Eg http://flybase.org/reports/FBgn0023036 - gene - - - "W, l(2)46Eg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,semidominant" embryonic/larval digestive system FBgn0038065 Snx3 Sorting nexin 3 http://flybase.org/reports/FBgn0038065 protein_coding_gene phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from sequence or structural similarity with HGNC:11174 phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 canonical Wnt signaling pathway ; GO:0060070 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype positive regulation of Wnt protein secretion ; GO:0061357 | inferred from mutant phenotype positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype Wnt protein secretion ; GO:0061355 | inferred from mutant phenotype regulation of Wnt signaling pathway by Wnt protein secretion ; GO:0061359 | inferred from mutant phenotype vesicle organization ; GO:0016050 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 extrinsic component of membrane ; GO:0019898 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 retromer complex ; GO:0030904 | inferred from physical interaction with Vps35 early endosome ; GO:0005769 | inferred from direct assay "CG6359, Dsnx3, Snx3, DmSNX3, snx3, lincRNA.S6645" IPR001683:Phox homologous domain CG6359 11-Aug-17 DroID_v2017_08 "Drer\snx10a, Drer\snx11, Drer\snx12, Drer\snx10b, Drer\snx3" "Scer\VPS17, Scer\ATG20, Scer\SNX41, Scer\YKR078W, Scer\SNX4, Scer\SNX3, Scer\VPS5, Scer\MVP1" Cele\snx-3 "Xtro\snx15, Xtro\snx11, Xtro\snx12, Xtro\snx3, Xtro\snx10" "Mmus\Snx12, Mmus\Snx10, Mmus\Snx11, Mmus\Snx3" "Hsap\SNX11, Hsap\SNX12, Hsap\SNX10, Hsap\SNX3" "viable,fertile,partially lethal - majority die" "wing margin,wing margin bristle,somatic clone,wing" FBgn0010415 Sdc Syndecan http://flybase.org/reports/FBgn0010415 FBgn0010667 protein_coding_gene - "positive regulation of gene silencing by miRNA ; GO:2000637 | inferred from mutant phenotype regulation of multicellular organismal metabolic process ; GO:0044246 | inferred from mutant phenotype detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype energy homeostasis ; GO:0097009 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with RGDID:3648 perivitelline space ; GO:0098595 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from mutant phenotype neuromuscular junction ; GO:0031594 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from sequence or structural similarity "Sdc, CG10497, Dsyn, syn, sdc, CT27296, l(2)10608, Syd, Syn, syd, dSdc" "IPR001050:Syndecan, IPR003585:Neurexin/syndecan/glycophorin C, IPR030479:Syndecan, conserved site, IPR027789:Syndecan/Neurexin domain, IPR031198:Syndecan, invertebrate" CG10497 11-Aug-17 DroID_v2017_08 "Drer\sdc4, Drer\sdc2, Drer\sdc3" - Cele\sdn-1 "Xtro\sdc1, Xtro\fam19a5, Xtro\sdc3" "Mmus\Sdc4, Mmus\Sdc2, Mmus\Sdc1, Mmus\Sdc3" "Hsap\SDC1, Hsap\SDC2, Hsap\SDC4, Hsap\SDC3" embryonic stage | 7-15 hr " embryonic stage | 13-16 hr , embryonic stage | stage 16 " " ventral midline

, embryonic/larval midgut

, peripheral nervous system

, embryonic/larval hindgut

, posterior commissure

, lymph gland

, longitudinal connective

, embryonic/larval pharynx

, anterior commissure

" "viable,fertile,neuroanatomy defective,neurophysiology defective,lethal,recessive,immune response defective,size defective,female limited,female semi-fertile,short lived,hypoactive,male limited,sleep defective,starvation stress response defective,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live" "dorsal branch,dorsal branch | third instar larval stage,synapse,embryonic/larval salivary gland,eye photoreceptor cell & axon,lamina plexus,medulla,presumptive embryonic/larval central nervous system,NMJ bouton,anterior fascicle & axon | ectopic,embryonic somatic muscle,ventral,lateral transverse muscle,muscle fiber,fascicle,ectopic,abdominal segmental nerve,NMJ bouton | larval stage,adult ganglionic branch,terminal tracheal cell,tracheal fusion cell" DRSC04654 K 0.011152823 0.478141259 -0.271455981 0.079588875 0.257226323 2.798436584 FBgn0022002 l(2)k09314b lethal (2) k09314b http://flybase.org/reports/FBgn0022002 - gene - - - "l(2)k09314, l(2)k09314b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0060644 l(3)S084014b lethal (3) S084014b http://flybase.org/reports/FBgn0060644 gene - - - "0840/14, l(3)S084014b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0062597 Mod(var)1515 Mod(var)1515 http://flybase.org/reports/FBgn0062597 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1515, Mod(var)1515" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0004942 AcpA Accessory gland protein A http://flybase.org/reports/FBgn0004942 - gene - - - AcpA - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036704 CG6497 - http://flybase.org/reports/FBgn0036704 protein_coding_gene - - - CG6497 IPR031754:Protein of unknown function DUF4736 CG6497 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC21469 IK 1.515529586 0.115235374 0.027906937 -0.275473706 1.564217441 0.234179804 FBgn0266643 CR45150 - http://flybase.org/reports/FBgn0266643 non_protein_coding_gene - - - CR45150 - CR45150 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060508 l(3)S104416b lethal (3) S104416b http://flybase.org/reports/FBgn0060508 gene - - - "1044/16, l(3)S104416b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085629 CG41348 - http://flybase.org/reports/FBgn0085629 protein_coding_gene - - - CG41348 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015516 lup-3 loop unfolding protein 3 http://flybase.org/reports/FBgn0015516 - gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "ms(2)HB108, lup-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "Y chromosome loop,spermatozoon" FBgn0267882 CR46170 - http://flybase.org/reports/FBgn0267882 pseudogene_attribute - - - "CR46170, CG12717-related" - CR46170 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065895 l(2)SH0212 lethal (2) SH0212 http://flybase.org/reports/FBgn0065895 gene - - - "l(2)SH0212, l(2)SH2 0212" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001165 gvl grooveless http://flybase.org/reports/FBgn0001165 - gene - - - gvl - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" scutellum FBgn0035206 CG9186 - http://flybase.org/reports/FBgn0035206 protein_coding_gene - sequestering of triglyceride ; GO:0030730 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay CG9186 "IPR019363:Lipid droplet-associated hydrolase, IPR029058:Alpha/Beta hydrolase fold" CG9186 11-Aug-17 DroID_v2017_08 Drer\ldah Scer\YPR147C "Cele\F11C1.10, Cele\F26A3.1, Cele\F11C1.4" Xtro\ldah Mmus\Ldah Hsap\LDAH viable "lipid particleSgs3.PD,embryonic/larval salivary gland | third instar larval stage,lipid particlefat,lipid particletub.PU" FBgn0011983 tRNA:Ser-AGA-2-2 transfer RNA:Serine-AGA 2-2 http://flybase.org/reports/FBgn0011983 "FBgn0003830, FBgn0011968, FBgn0011979, FBgn0052609, FBgn0060069" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "tRNA ser7, 777-2, Ser-tRNA-7, tRNA[Ser][[7]], tRNA[Ser], tRNA[[7]][Ser], AE002593.trna11-SerAGA, tRNA:S:AGA:AE002593-c, CR32609, tRNA:ser, tRNA:S, tRNA:S7, tRNA:ser7, tRNA:ser7:12Eg, tRNA[[Ser]], chrX.trna20-SerAGA, tRNA-Ser-AGA-2-2, tRNA:Ser-AGA-2-2, tRNA:S7:12Eg, UCU" - CR32609 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030313 CG11697 - http://flybase.org/reports/FBgn0030313 protein_coding_gene - - - "a, anon-WO03040301.203, CG11697" IPR004345:TB2/DP1/HVA22-related protein CG11697 11-Aug-17 DroID_v2017_08 "Drer\reep3b, Drer\reep1, Drer\reep5, Drer\reep2, Drer\reep3a" Scer\YOP1 "Cele\Y110A2AR.1, Cele\T19C3.4, Cele\yop-1" "Xtro\reep4, Xtro\reep3" "Mmus\Reep3, Mmus\Reep2, Mmus\Reep5, Mmus\Reep1, Mmus\Reep4" "Hsap\REEP2, Hsap\REEP5, Hsap\REEP4, Hsap\REEP1, Hsap\REEP3" DRSC19418 K -0.325502029 0.804681252 0.237684872 0.259733164 -0.584223611 -1.550965857 FBgn0266674 Sec15 Secretory 15 http://flybase.org/reports/FBgn0266674 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab11 vesicle docking involved in exocytosis ; GO:0006904 | inferred from electronic annotation with InterPro:IPR007225 vesicle tethering involved in exocytosis ; GO:0090522 | inferred by curator from GO:0000145 synaptic vesicle docking ; GO:0016081 | non-traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle targeting ; GO:0016080 | non-traceable author statement endosome ; GO:0005768 | inferred from direct assay exocyst ; GO:0000145 | inferred from direct assay axon terminus ; GO:0043679 | inferred from direct assay exocyst ; GO:0000145 | inferred from sequence or structural similarity recycling endosome ; GO:0055037 | inferred from direct assay exocyst ; GO:0000145 | non-traceable author statement cytoplasmic vesicle ; GO:0031410 | inferred from direct assay endosome ; GO:0005768 | "sec15, Sec15, CG7034, Sec15p, dsec15, 3R41" IPR007225:Exocyst complex component EXOC6/Sec15 CG7034 11-Aug-17 DroID_v2017_08 "Drer\exoc6b, Drer\exoc6" Scer\SEC15 Cele\sec-15 "Xtro\exoc6, Xtro\exoc6b" "Mmus\Exoc6, Mmus\Exoc6b" "Hsap\EXOC6, Hsap\EXOC6B" FBgn0267042 CG45486 - http://flybase.org/reports/FBgn0267042 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45486 - CG45486 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027490 D12 D12 http://flybase.org/reports/FBgn0027490 - protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR005033 histone acetylation ; GO:0016573 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay" Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from physical interaction with Ada2a Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "CG13400, D12, Yeats2" IPR005033:YEATS CG13400 11-Aug-17 DroID_v2017_08 "Drer\yeats4, Drer\yeats2, Drer\mllt3, Drer\mllt1a, Drer\mllt1b" "Scer\TAF14, Scer\YAF9, Scer\SAS5" - "Xtro\mllt3, Xtro\mllt1, Xtro\yeats2, Xtro\yeats4" "Mmus\Yeats4, Mmus\Mllt1, Mmus\Mllt3, Mmus\Yeats2" "Hsap\YEATS4, Hsap\MLLT1, Hsap\YEATS2, Hsap\MLLT3" viable FBgn0052336 CG32336 - http://flybase.org/reports/FBgn0052336 protein_coding_gene - - - CG32336 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052667 ssp7 short spindle 7 http://flybase.org/reports/FBgn0052667 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG32667, CG32677, ssp7, Ssp7" IPR029277:Single domain Von Willebrand factor type C domain CG32667 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" FBgn0024870 l(2)k13215 lethal (2) k13215 http://flybase.org/reports/FBgn0024870 - gene - - - l(2)k13215 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal" FBgn0263760 CG43677 - http://flybase.org/reports/FBgn0263760 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43677 - CG43677 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265545 CR44395 - http://flybase.org/reports/FBgn0265545 non_protein_coding_gene - - - CR44395 - CR44395 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003596 Su(var)3-5 Suppressor of variegation 3-5 http://flybase.org/reports/FBgn0003596 - gene - - - "Su-var5, Su(var)3-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,recessive,female sterile,male sterile,chemical sensitive,suppressor of variegation,dominant" FBgn0014995 osk::Dvir\osk osk::Dvir\osk http://flybase.org/reports/FBgn0014995 - engineered_fusion_gene - - - osk::Dvir\osk - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,dominant" "embryo,maternal effect" FBgn0037262 MED31 Mediator complex subunit 31 http://flybase.org/reports/FBgn0037262 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from electronic annotation with InterPro:IPR008831 transcription coactivator activity ; GO:0003713 | contributes_to inferred from direct assay RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VS38 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype" mediator complex ; GO:0016592 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN000323967 mediator complex ; GO:0016592 | inferred from sequence or structural similarity "Med31, Trap18, dSOH1, p36, dTRAP18, CG1057, BcDNA:GM28912, MED31, med31" "IPR008831:Mediator complex, subunit Med31" CG1057 11-Aug-17 DroID_v2017_08 Drer\med31 Scer\SOH1 Cele\mdt-31 Xtro\med31 Mmus\Med31 Hsap\MED31 "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,cell growth defective,lethal - all die before end of pupal stage,some die during pupal stage" "mitotic domain,non-rescuable maternal effect,pole cell,tergite,maternal effect,adult epidermis,sternite,haltere" FBgn0085727 CG42200 - http://flybase.org/reports/FBgn0085727 protein_coding_gene - - - CG42200 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051300 CG31300 - http://flybase.org/reports/FBgn0051300 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG13657, CG31300" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG31300 11-Aug-17 DroID_v2017_08 - - "Cele\nhr-246, Cele\D1044.1, Cele\H06H21.8, Cele\dhs-27, Cele\C29F7.1, Cele\F59B1.10, Cele\C29F7.2" - - - viable FBgn0027786 Mtch Mitochondrial carrier homolog 1 http://flybase.org/reports/FBgn0027786 - protein_coding_gene - positive regulation of apoptotic process ; GO:0043065 | inferred from biological aspect of ancestor with PANTHER:PTN001324730 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001324730 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001324730 "CG6851, Mtch" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG6851 11-Aug-17 DroID_v2017_08 Drer\mtch2 "Scer\RIM2, Scer\YIA6" "Cele\mtch-1, Cele\F43E2.11" Xtro\mtch2 "Mmus\Mtch2, Mmus\Mtch1" "Hsap\MTCH1, Hsap\MTCH2" "neuroanatomy defective,viable,visible" "mushroom body & axon7B,Kenyon cell,adult mushroom body,mushroom body & axonc739,trichogen cell" FBgn0050147 Hil Hillarin http://flybase.org/reports/FBgn0050147 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40797 - cell cortex ; GO:0005938 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay "CG30147, CG13435, CG10439, Hil, D-hil" "IPR001781:Zinc finger, LIM-type, IPR002931:Transglutaminase-like" CG30147 11-Aug-17 DroID_v2017_08 "Drer\mical2a, Drer\mical3b, Drer\ky, Drer\mical1, Drer\mical3a, Drer\mical2b" Scer\CYK3 Cele\ltd-1 "Xtro\mical2, Xtro\mical3" "Mmus\Ky, Mmus\Mical3, Mmus\Mical1, Mmus\Mical2" "Hsap\MICAL2, Hsap\MICAL1, Hsap\MICAL3, Hsap\KY" "viable,visible" trichogen cell FBgn0004066 Prosalpha4 Proteasome alpha4 subunit http://flybase.org/reports/FBgn0004066 - protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR000426 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426 proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay" "alpha4, a4, pros28.1, PROS-Dm28.1, PROSA-28.1, alpha4_dm, Pros28, PROS-28.1, Pros-Dm28.1, CG3422, 28.1Pros, 3422, Prosalpha4, PSA4_DROME, Alpha-4, Pros28.1, alpha-4" "IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR023332:Proteasome alpha-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG3422 11-Aug-17 DroID_v2017_08 "Drer\psma8, Drer\psma2, Drer\psma4" "Scer\PRE6, Scer\PRE9" "Cele\pas-4, Cele\pas-3" "Xtro\psma5, Xtro\psma7, Xtro\psma4, Xtro\psma2" "Mmus\Psma7, Mmus\Psma5, Mmus\Psma8, Mmus\Psma2, Mmus\Psma4" "Hsap\PSMA2, Hsap\PSMA7, Hsap\PSMA8, Hsap\PSMA4, Hsap\PSMA5" viable FBgn0033615 CG7741 - http://flybase.org/reports/FBgn0033615 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011146 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7741 "IPR006767:Cwf19-like protein, C-terminal domain-2, IPR006768:Cwf19-like, C-terminal domain-1, IPR011146:HIT-like domain, IPR029052:Metallo-dependent phosphatase-like" CG7741 11-Aug-17 DroID_v2017_08 Drer\cwf19l1 Scer\DRN1 Cele\F17A9.2 "Xtro\cwf19l1, Xtro\cwf19l2" Mmus\Cwf19l1 Hsap\CWF19L1 viable FBgn0262112 sro shroud http://flybase.org/reports/FBgn0262112 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype - "sro, CG12068" "IPR016040:NAD(P)-binding domain, IPR002347:Short-chain dehydrogenase/reductase SDR, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG12068 11-Aug-17 DroID_v2017_08 "Drer\rdh1, Drer\hsd17b1, Drer\bdh1, Drer\dhrs9, Drer\hsd11b2, Drer\hsd17b2, Drer\rdh5, Drer\zgc:113142" "Scer\AYR1, Scer\TDA5, Scer\LYS2" "Cele\dhs-2, Cele\dhs-16, Cele\drd-5, Cele\dhs-20" "Xtro\hsd17b6, Xtro\hsd17b2, Xtro\MGC89248, Xtro\LOC100124842, Xtro\rdh16, Xtro\dhrs9, Xtro\LOC100170425, Xtro\rdh7, Xtro\hsd11b2, Xtro\rdh7.2, Xtro\bdh1, Xtro\rdh5" "Mmus\Hsd11b2, Mmus\Rdh5, Mmus\BC089597, Mmus\Bdh1, Mmus\Hsd17b6, Mmus\Rdh7, Mmus\Hsd17b2, Mmus\Rdh9, Mmus\Rdh19, Mmus\Rdh16, Mmus\Dhrs9, Mmus\Sdr9c7, Mmus\Rdh1, Mmus\Hsd17b1" "Hsap\RDH16, Hsap\RDH5, Hsap\SDR9C7, Hsap\HSD17B2, Hsap\HSD17B6, Hsap\DHRS9, Hsap\BDH1, Hsap\HSD17B1, Hsap\HSD11B2" FBgn0001355 l(1)1EFd lethal (1) 1EFd http://flybase.org/reports/FBgn0001355 - gene - - - "l(1)BA4, l(1)1EFd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0082678 E(ftz)4758 E(ftz)4758 http://flybase.org/reports/FBgn0082678 gene - - - "4758, E(ftz)4758" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086223 Chifoumi Chifoumi http://flybase.org/reports/FBgn0086223 gene - - - Chifoumi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022770 Peritrophin-A Peritrophin A http://flybase.org/reports/FBgn0022770 - protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "PeriA, CG17058, Peritrophin-A, obst-D, CG31559" IPR002557:Chitin binding domain CG17058 11-Aug-17 DroID_v2017_08 - - "Cele\cbd-1, Cele\dct-9, Cele\cpg-2, Cele\R02F2.4" - - - viable FBgn0004517 l(4)102ABd lethal (4) 102ABd http://flybase.org/reports/FBgn0004517 - gene - - - "l(4)Abd, l(4)1, l(4)32, l(4)30, l(4)28, l(4)27, l(4)102ABd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0014907 anon-4Fa anon-4Fa http://flybase.org/reports/FBgn0014907 - gene - - - anon-4Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050035 Tret1-1 Trehalose transporter 1-1 http://flybase.org/reports/FBgn0050035 protein_coding_gene trehalose transmembrane transporter activity ; GO:0015574 | inferred from direct assay glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 trehalose transport ; GO:0015771 | inferred from direct assay maltose transport ; GO:0015768 | NOT inferred from direct assay hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 lactose transport ; GO:0015767 | NOT inferred from direct assay sucrose transport ; GO:0015770 | NOT inferred from direct assay "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829 membrane ; GO:0016020 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay" "CG7801, CG7797, Tret1-1, CG30035, DmTret1-1, Tre T1" "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG30035 11-Aug-17 DroID_v2017_08 "Drer\slc2a8, Drer\si:ch1073-263o8.2, Drer\si:dkey-229d11.5, Drer\slc2a12, Drer\slc2a13b, Drer\slc2a1b, Drer\LOC797974, Drer\slc2a1a, Drer\slc2a6, Drer\LOC101882338, Drer\slc2a10" "Scer\HXT4, Scer\YMR279C, Scer\HXT16, Scer\HXT6, Scer\ITR2, Scer\GAL2, Scer\ENB1, Scer\STL1, Scer\HXT2, Scer\HXT17, Scer\AZR1, Scer\YFL040W, Scer\HXT15, Scer\MPH2, Scer\HXT11, Scer\MAL31, Scer\HXT1, Scer\MAL11, Scer\VBA5, Scer\HXT3, Scer\HXT13, Scer\HXT10, Scer\VBA2, Scer\SNF3, Scer\VBA1, Scer\HXT7, Scer\YDL199C, Scer\YBR241C, Scer\YDR387C, Scer\HXT9, Scer\ATR1, Scer\HXT14, Scer\VBA3, Scer\MPH3, Scer\VBA4, Scer\RGT2, Scer\HXT5, Scer\SGE1, Scer\ITR1, Scer\GEX1, Scer\HXT8, Scer\GEX2" "Cele\hmit-1.1, Cele\hmit-1.2, Cele\Y66D12A.21, Cele\F48E3.2, Cele\hmit-1.3, Cele\M01G12.14, Cele\fgt-1, Cele\M01G12.9" "Xtro\slc2a10, Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a12" "Mmus\Slc2a4, Mmus\Acrv1, Mmus\Tm2d1, Mmus\Slc2a6, Mmus\Slc2a2, Mmus\Pate1, Mmus\Pate3, Mmus\Slc2a3, Mmus\Slc2a10, Mmus\Gm17689, Mmus\1700013H16Rik, Mmus\Slc2a1, Mmus\Gm7257, Mmus\Gm5615, Mmus\Pate4, Mmus\Slc2a12, Mmus\Slc2a13, Mmus\Slc2a8" "Hsap\PATE1, Hsap\PATE3, Hsap\SLC2A10, Hsap\SLC2A1, Hsap\ACRV1, Hsap\SLC2A8, Hsap\PATE4, Hsap\SLC2A13, Hsap\SLC2A3, Hsap\TM2D1, Hsap\SLC2A4, Hsap\SLC2A12, Hsap\SLC2A6" viable FBgn0005494 l(1)ts5569 lethal (1) ts5569 http://flybase.org/reports/FBgn0005494 - gene - - - l(1)ts5569 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0040628 CG18672 - http://flybase.org/reports/FBgn0040628 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from electronic annotation with InterPro:IPR018338 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR018338 - CG18672 "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class, IPR018338:Carbonic anhydrase, alpha-class, conserved site" CG18672 11-Aug-17 DroID_v2017_08 "Drer\ca12, Drer\ca10a, Drer\ca15a, Drer\ptprga, Drer\ca5a, Drer\ca6, Drer\zgc:153760, Drer\ca14, Drer\ca8, Drer\ca7, Drer\ca4c, Drer\ca15c, Drer\ca4a, Drer\ca2, Drer\ca16b, Drer\cahz, Drer\ca9, Drer\si:ch211-173d10.4, Drer\ca15b, Drer\ca4b, Drer\ca10b, Drer\car15" - "Cele\cah-4, Cele\cah-5, Cele\cah-3, Cele\cah-6" "Xtro\ca10, Xtro\LOC779564, Xtro\ca6, Xtro\ca2, Xtro\ca8, Xtro\ca11, Xtro\ca3, Xtro\ca4, Xtro\ca5b, Xtro\ca7, Xtro\ca14, Xtro\ca1, Xtro\ca12" "Mmus\Car6, Mmus\Car7, Mmus\Car8, Mmus\Ptprg, Mmus\Car5b, Mmus\Car10, Mmus\Car13, Mmus\Car2, Mmus\Car5a, Mmus\Car4, Mmus\Car3, Mmus\Car15, Mmus\Car9, Mmus\Car14, Mmus\Car12, Mmus\Car11, Mmus\Car1" "Hsap\CA3, Hsap\PTPRG, Hsap\CA10, Hsap\CA1, Hsap\CA12, Hsap\CA5B, Hsap\CA7, Hsap\CA8, Hsap\CA11, Hsap\CA2, Hsap\CA6, Hsap\CA13, Hsap\CA14, Hsap\CA4, Hsap\CA5A, Hsap\CA9" viable DRSC15371 K -0.082413136 0.45188094 -0.014645669 0.451437021 -1.569937634 0.151019461 FBgn0053643 CG33643 - http://flybase.org/reports/FBgn0053643 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33643 IPR010512:Protein of unknown function DUF1091 CG33643 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266627 CR45134 - http://flybase.org/reports/FBgn0266627 non_protein_coding_gene - - - CR45134 - CR45134 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065776 l(2)SH0453 lethal (2) SH0453 http://flybase.org/reports/FBgn0065776 gene - - - "l(2)SH0453, l(2)SH2 0453" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014273 l(2)k11512 lethal (2) k11512 http://flybase.org/reports/FBgn0014273 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc growth ; GO:0007446 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)115/12, l(2)k11512" - - 11-Aug-17 DroID_v2017_08 - - - - - - "hyperplasia,lethal - all die before end of pupal stage,some die during pupal stage" "prothoracic leg disc,mesothoracic leg disc,metathoracic leg disc,embryonic/larval brain" FBgn0262330 mir-193 mir-193 stem loop http://flybase.org/reports/FBgn0262330 miRNA_gene - - - "dme-mir-193, miR-193, mir-193, MIR-193, CR43037" - CR43037 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing vein L5,wing vein" FBgn0004784 inaC inactivation no afterpotential C http://flybase.org/reports/FBgn0004784 "FBgn0001262, FBgn0003092" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR014375, InterPro:IPR017441, InterPro:IPR017892 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR014375 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24008 protein kinase C activity ; GO:0004697 | inferred from sequence or structural similarity with protein_id:AAA41871.1 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 positive regulation of clathrin-dependent endocytosis ; GO:2000370 | inferred from genetic interaction with Pkc53E deactivation of rhodopsin mediated signaling ; GO:0016059 | traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 protein phosphorylation ; GO:0006468 | non-traceable author statement adaptation of rhodopsin mediated signaling ; GO:0016062 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype detection of light stimulus involved in sensory perception ; GO:0050962 | inferred from mutant phenotype calcium-mediated signaling ; GO:0019722 | traceable author statement adaptation of rhodopsin mediated signaling ; GO:0016062 | inferred from genetic interaction with UniProtKB:Q24008 response to light stimulus ; GO:0009416 | inferred from mutant phenotype adaptation of rhodopsin mediated signaling ; GO:0016062 | non-traceable author statement response to ethanol ; GO:0045471 | inferred from direct assay phototransduction ; GO:0007602 | inferred from genetic interaction with rdgB cell migration ; GO:0016477 | inferred from mutant phenotype female gonad development ; GO:0008585 | inferred from mutant phenotype phospholipase C-inhibiting G-protein coupled receptor signaling pathway ; GO:0030845 | inferred from mutant phenotype endosome ; GO:0005768 | colocalizes_with inferred from direct assay inaD signaling complex ; GO:0016027 | traceable author statement rhabdomere ; GO:0016028 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "InaC, PKC, INAC, CG6518, eye PKC, PKCi, eye-PKC, PKC 53E, ePKC, dPKC53E(ey), Dpkc2, pkc-2, dPKC53E, Pkc2, inaC, eyePKC, PK-C, PKC2, inac, PKCinac" "IPR000008:C2 domain, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR014375:Protein kinase C, alpha/beta/gamma types, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal, IPR020454:Diacylglycerol/phorbol-ester binding" CG6518 11-Aug-17 DroID_v2017_08 "Drer\prkcg, Drer\prkcda, Drer\prkcha, Drer\prkceb, Drer\pimr112, Drer\prkcea, Drer\si:ch211-14c7.2, Drer\prkcba, Drer\si:ch73-374l24.1, Drer\prkca, Drer\prkcbb, Drer\prkcq, Drer\prkchb" Scer\PKC1 "Cele\tpa-1, Cele\pkc-1, Cele\pkc-2" "Xtro\prkcg, Xtro\prkch, Xtro\prkcb, Xtro\prkce, Xtro\prkcd, Xtro\prkca, Xtro\prkcq" "Mmus\Prkce, Mmus\Prkcb, Mmus\Prkch, Mmus\Sprr1a, Mmus\Prx, Mmus\Gm5113, Mmus\Prkcd, Mmus\Prkcq, Mmus\Prkcg, Mmus\Prkca, Mmus\D130040H23Rik, Mmus\Sprr1b, Mmus\Cpne8" "Hsap\PRKCH, Hsap\CPNE8, Hsap\PRX, Hsap\PRKCD, Hsap\PRKCB, Hsap\PRKCA, Hsap\PRKCE, Hsap\PRKCG, Hsap\PRKCQ" " adult stage , pupal stage | late " " ocellus

, eye

, head

, photoreceptor cell

" adult stage " eye

, ocellus

, rhabdomere

" "viable,fertile,wild-type,visual behavior defective,recessive,neurophysiology defective,semidominant,behavior defective,chemical resistant" "photoreceptor cell,photoreceptor,eye,retina,ovary,germarium,egg chamber,ovarian sheath,gustatory receptor neuron" FBgn0265304 CR44277 - http://flybase.org/reports/FBgn0265304 non_protein_coding_gene - - - CR44277 - CR44277 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262536 CG43090 - http://flybase.org/reports/FBgn0262536 protein_coding_gene chaperone binding ; GO:0051087 | inferred from electronic annotation with InterPro:IPR003103 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43090 IPR003103:BAG domain CG43090 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061119 l(3)S005115 lethal (3) S005115 http://flybase.org/reports/FBgn0061119 gene - - - "0051/15, l(3)S005115" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0046999 CG6429 - http://flybase.org/reports/FBgn0046999 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR008597 - - "BcDNA:RH62928, CG6429" "IPR008597:Destabilase, IPR023346:Lysozyme-like domain" CG6429 11-Aug-17 DroID_v2017_08 - - "Cele\ilys-5, Cele\ilys-6, Cele\ilys-3, Cele\ilys-1, Cele\ilys-4, Cele\ilys-2" - - - viable DRSC06986 I -0.326470116 2.424769143 0.239269972 0.291995136 -0.041039761 0.386532504 FBgn0030349 CG10353 - http://flybase.org/reports/FBgn0030349 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR032394 intracellular calcium activated chloride channel activity ; GO:0005229 | inferred from sequence or structural similarity with HGNC:25240 chloride transport ; GO:0006821 | inferred from sequence or structural similarity with HGNC:25240 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:25240 CG10353 "IPR007632:Anoctamin, IPR032394:Anoctamin, dimerisation domain" CG10353 11-Aug-17 DroID_v2017_08 "Drer\ano8b, Drer\si:dkey-83h2.5, Drer\LOC101886884, Drer\ano2, Drer\LOC562630, Drer\ano5b, Drer\ano5a, Drer\LOC563500, Drer\ano11, Drer\ano3, Drer\ano9b, Drer\ano8a, Drer\ano6, Drer\LOC103910000, Drer\ano1" Scer\IST2 "Cele\anoh-1, Cele\anoh-2" "Xtro\ano5, Xtro\ano1, Xtro\ano2, Xtro\ano9, Xtro\ano3" "Mmus\Ano6, Mmus\Ano5, Mmus\Ano9, Mmus\Ano2, Mmus\Ano3, Mmus\Ano1, Mmus\Ano8, Mmus\Ano4, Mmus\Ano7" "Hsap\ANO6, Hsap\ANO5, Hsap\ANO8, Hsap\ANO1, Hsap\ANO4, Hsap\ANO7, Hsap\ANO2, Hsap\ANO3, Hsap\ANO9" viable FBgn0086299 lackluster lackluster http://flybase.org/reports/FBgn0086299 gene - - - "lackluster, lack" - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0033863 CG13337 - http://flybase.org/reports/FBgn0033863 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13337 - CG13337 11-Aug-17 DroID_v2017_08 - - - - Mmus\Trdn Hsap\CALD1 viable FBgn0266007 CR44780 - http://flybase.org/reports/FBgn0266007 non_protein_coding_gene - - - CR44780 - CR44780 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259304 EP-112 - http://flybase.org/reports/FBgn0259304 gene - - - EP-112 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta" FBgn0060641 l(3)S084204b lethal (3) S084204b http://flybase.org/reports/FBgn0060641 gene - - - "0842/04, l(3)S084204b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0026346 Su(dpp)39CDE Su(dpp)39CDE http://flybase.org/reports/FBgn0026346 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available Su(dpp)39CDE - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0263482 snoRNA:lola-c - http://flybase.org/reports/FBgn0263482 snoRNA_gene - - - snoRNA:lola-c - CR43597 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039316 CG11893 - http://flybase.org/reports/FBgn0039316 protein_coding_gene - chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp inferred from genetic interaction with Chi wing disc development ; GO:0035220 | inferred from genetic interaction with Bx inferred from genetic interaction with ap - CG11893 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG11893 11-Aug-17 DroID_v2017_08 - - "Cele\C29F7.1, Cele\D1044.1, Cele\nhr-246, Cele\F59B1.10, Cele\H06H21.8, Cele\C29F7.2, Cele\dhs-27" - - - "viable,fertile,planar polarity defective" FBgn0033954 CG12860 - http://flybase.org/reports/FBgn0033954 protein_coding_gene - - - "bs33f06.y1, anon-WO0140519.75, CG12860" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG12860 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030752 CG9947 - http://flybase.org/reports/FBgn0030752 protein_coding_gene - phospholipid transport ; GO:0015914 | inferred from electronic annotation with InterPro:IPR030351 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR030351 CG9947 "IPR005045:CDC50/LEM3 family, IPR030351:Cell cycle control protein 50A" CG9947 11-Aug-17 DroID_v2017_08 "Drer\tmem30ab, Drer\tmem30aa, Drer\zgc:91908, Drer\tmem30c" "Scer\YNR048W, Scer\CDC50, Scer\LEM3" "Cele\F20C5.4, Cele\W03G11.2, Cele\chat-1" "Xtro\tmem30b, Xtro\tmem30c, Xtro\tmem30a" "Mmus\Tmem30b, Mmus\Tmem30a, Mmus\Tmem30c" "Hsap\TMEM30B, Hsap\TMEM30A" "partially lethal - majority die,some die during pupal stage" FBgn0266508 s-436 - http://flybase.org/reports/FBgn0266508 gene - - - s-436 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037620 ranshi ranshi http://flybase.org/reports/FBgn0037620 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "oocyte differentiation ; GO:0009994 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 germarium-derived oocyte differentiation ; GO:0030706 | inferred from mutant phenotype" exon-exon junction complex ; GO:0035145 | inferred from physical interaction with mago inferred from physical interaction with tsu "CG9793, ranshi" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9793 11-Aug-17 DroID_v2017_08 "Drer\znf341, Drer\znf408, Drer\znf770, Drer\bcl6ab" - "Cele\klf-3, Cele\lin-29, Cele\blmp-1, Cele\Y37F4.6, Cele\eor-1, Cele\ztf-23, Cele\Y55F3AM.14, Cele\M03D4.4" - "Mmus\Zfp810, Mmus\Zfp280b, Mmus\Zfp62, Mmus\Zfp708, Mmus\Zbtb6, Mmus\Zfp945, Mmus\Zfp110, Mmus\Zkscan8, Mmus\Zfp341, Mmus\Zscan5b, Mmus\Zfp445, Mmus\Zfp12, Mmus\Zfp93, Mmus\Zfp369, Mmus\Rbak, Mmus\Zfp758, Mmus\Zfp24, Mmus\Gm13212, Mmus\Zfp612, Mmus\Zfp984" "Hsap\ZNF221, Hsap\ZNF730, Hsap\ZFP28, Hsap\ZNF595, Hsap\ZNF570, Hsap\ZNF560, Hsap\ZNF480, Hsap\ZNF572, Hsap\ZNF160, Hsap\ZNF254, Hsap\ZNF721, Hsap\ZNF98, Hsap\ZNF845, Hsap\ZNF117, Hsap\ZNF70, Hsap\ZNF582, Hsap\ZNF341, Hsap\ZNF850, Hsap\ZNF675, Hsap\ZNF281, Hsap\ZNF280A, Hsap\ZNF8, Hsap\ZNF784, Hsap\ZNF816, Hsap\ZNF485, Hsap\ZNF681, Hsap\ZNF43, Hsap\RBAK-RBAKDN, Hsap\ZNF233, Hsap\ZNF492, Hsap\ZNF761, Hsap\ZSCAN30, Hsap\ZNF708, Hsap\ZNF558, Hsap\ZNF28, Hsap\ZNF468, Hsap\ZNF792, Hsap\ZNF211, Hsap\ZNF284, Hsap\ZNF528, Hsap\ZNF568, Hsap\ZNF527" "viable,fertile,male fertile,female sterile" "karyosome,germarium region 3,synaptonemal complex" FBgn0033605 CG9067 - http://flybase.org/reports/FBgn0033605 protein_coding_gene - ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from electronic annotation with InterPro:IPR006722 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR006722 "CG9067, Tca17, TRAPPC2L" "IPR011012:Longin-like domain, IPR006722:Trafficking protein particle complex subunit 2" CG9067 11-Aug-17 DroID_v2017_08 Drer\trappc2l - "Cele\trpp-4, Cele\T10F2.5" Xtro\trappc2l Mmus\Trappc2l Hsap\TRAPPC2L "viable,fertile" FBgn0267100 CR45540 - http://flybase.org/reports/FBgn0267100 non_protein_coding_gene - - - CR45540 - CR45540 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262889 CG43244 - http://flybase.org/reports/FBgn0262889 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43244 - CG43244 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083049 snoRNA:Psi18S-1377c snoRNA:Psi18S-1377c http://flybase.org/reports/FBgn0083049 snoRNA_gene - - - "snoRNA:Psi18S-1377c, Psi18S-1377c, psi18S-1377c, CR34627, chr3R:26033056..26033194" - CR34627 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038959 CG13856 - http://flybase.org/reports/FBgn0038959 protein_coding_gene - - - CG13856 IPR031983:Protein of unknown function DUF4786 CG13856 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013450 fs(2)ry6 fs(2)ry6 http://flybase.org/reports/FBgn0013450 - gene - - - "fs(2)6, fs(2)ry6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,poor,female sterile" FBgn0037378 CG2046 - http://flybase.org/reports/FBgn0037378 protein_coding_gene - proteasome assembly ; GO:0043248 | inferred from electronic annotation with InterPro:IPR016565 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN001431032 proteasome complex ; GO:0000502 | colocalizes_with inferred from direct assay CG2046 IPR016565:Proteasome assembly chaperone 1 CG2046 11-Aug-17 DroID_v2017_08 Drer\psmg1 - - - Mmus\Psmg1 Hsap\PSMG1 "viable,fertile" FBgn0083292 E(smoDN)203 Enhancer of smoDN 203 http://flybase.org/reports/FBgn0083292 gene - - - E(smoDN)203 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013243 E(var)236 E(var)236 http://flybase.org/reports/FBgn0013243 - gene - - - E(var)236 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0266232 CR44927 - http://flybase.org/reports/FBgn0266232 non_protein_coding_gene - - - "CR44927, lincRNA.686" - CR44927 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002272 l(3)69Bd lethal (3) 69Bd http://flybase.org/reports/FBgn0002272 - gene - - - "rsg34, l(3)rsg34, l(3)69Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065186 l(2)SH2348 lethal (2) SH2348 http://flybase.org/reports/FBgn0065186 gene - - - "l(2)SH2348, l(2)SH2 2348" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036833 CG3819 - http://flybase.org/reports/FBgn0036833 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - "CT12789, CG3819" IPR001604:DNA/RNA non-specific endonuclease CG3819 11-Aug-17 DroID_v2017_08 "Drer\LOC103910196, Drer\si:ch211-133n4.4, Drer\endog, Drer\LOC100333474" Scer\NUC1 Cele\cps-6 - Mmus\Endog Hsap\ENDOG "viable,planar polarity defective" FBgn0022715 19w 19w http://flybase.org/reports/FBgn0022715 - gene - - - 19w - - 11-Aug-17 DroID_v2017_08 - - - - - - mitotic cell cycle defective larval brain & nuclear chromosome FBgn0023407 B4 B4 http://flybase.org/reports/FBgn0023407 FBgn0040974 protein_coding_gene - circadian rhythm ; GO:0007623 | inferred from expression pattern imaginal disc development ; GO:0007444 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "B4, n(2)05337, BG:DS07660.4, CG9260, CG9239, B4/Susi, Susi" IPR025946:CABIT domain CG9239 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , larval stage | third instar " " sensory mother cell

, neuroblast

, imaginal disc | ubiquitous

,

ubiquitous " "viable,fertile,visible,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,large body,decreased cell number,somatic clone,decreased cell size,cell non-autonomous,small body" "imaginal disc,wing,wing vein,eye,ommatidium,eye photoreceptor cell,cell non-autonomous,somatic clone,trichogen cell" DRSC01868 I -0.349250766 6.010795913 0.31803317 0.521555461 -0.979776385 -1.351511492 FBgn0002901 mus304 mutagen-sensitive 304 http://flybase.org/reports/FBgn0002901 "FBgn0036776, FBgn0044544" protein_coding_gene - female meiotic division ; GO:0007143 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | traceable author statement telomere maintenance ; GO:0000723 | inferred from genetic interaction with tefu mitotic cell cycle checkpoint ; GO:0007093 | traceable author statement regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs mitotic DNA replication checkpoint ; GO:0033314 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype response to radiation ; GO:0009314 | traceable author statement DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype cytoplasm ; GO:0005737 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "mus-304, CG7347, mus(3)304, anon-WO0140519.82, mus304, Mus304, ATRIP, atrip" IPR033349:ATR-interacting protein CG7347 11-Aug-17 DroID_v2017_08 Drer\atrip - - Xtro\atrip Mmus\Atrip Hsap\ATRIP "viable,visible,recessive,chemical sensitive,radiation sensitive,meiotic cell cycle defective,mitotic cell cycle defective,increased cell death,DNA repair defective,wild-type" "macrochaeta,cycle 12 embryo,cycle 13 embryo,cycle 14 embryo,mitotic cell cycle,mitosis & nuclear chromosome,nucleus | embryonic stage,wing disc,mesothoracic tergum" FBgn0003057 CG10598 - http://flybase.org/reports/FBgn0003057 - protein_coding_gene - - - "anon-Pen15EF, GCR 17, GCR-11, pen15EF, Pen15EF, GCR17, GCR11, CG10598" - CG10598 11-Aug-17 DroID_v2017_08 - - Cele\grl-23 - - - FBgn0037690 Task7 TWIK-related acid-sensitive K[+] channel 7 http://flybase.org/reports/FBgn0037690 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Task6 potassium channel activity ; GO:0005267 | inferred from direct assay potassium ion transmembrane transport ; GO:0071805 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "CG9361, Task7, dTASK-7, K2P-TASK7" "IPR003092:Two pore domain potassium channel, TASK family, IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG9361 11-Aug-17 DroID_v2017_08 "Drer\kcnk13b, Drer\kcnk15, Drer\kcnk3a, Drer\kcnk18, Drer\kcnk3b, Drer\kcnk12l, Drer\kcnk9, Drer\kcnk12, Drer\kcnk10a, Drer\kcnk13a" Scer\TOK1 "Cele\sup-9, Cele\twk-20, Cele\twk-7" "Xtro\kcnk15, Xtro\kcnk9, Xtro\kcnk12" "Mmus\Kcnk13, Mmus\Kcnk12, Mmus\Kcnk2, Mmus\Kcnk10, Mmus\Kcnk9, Mmus\Kcnk18, Mmus\Kcnk3, Mmus\Kcnk15" "Hsap\KCNK2, Hsap\KCNK9, Hsap\KCNK13, Hsap\KCNK12, Hsap\KCNK10, Hsap\KCNK3, Hsap\KCNK15, Hsap\KCNK18" "viable,fertile" FBgn0001095 gcd giant cell defect http://flybase.org/reports/FBgn0001095 - gene - - - gcd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005269 l(3)SG89 lethal (3) SG89 http://flybase.org/reports/FBgn0005269 - gene - - - l(3)SG89 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0061492 loj logjam http://flybase.org/reports/FBgn0061492 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence model transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR009038 Golgi vesicle transport ; GO:0048193 | inferred from sequence model oviposition ; GO:0018991 | inferred from mutant phenotype reproduction ; GO:0000003 | inferred from mutant phenotype regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from sequence model cis-Golgi network ; GO:0005801 | inferred from direct assay endoplasmic reticulum-Golgi intermediate compartment ; GO:0005793 | inferred from direct assay "CG10733, l(3)04026, loj, p24, LOJ" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG10733 11-Aug-17 DroID_v2017_08 "Drer\tmed1a, Drer\tmed5, Drer\tmed6" "Scer\ERP3, Scer\ERP4, Scer\ERP2" Cele\C26C6.9 "Xtro\tmed1, Xtro\tmed5, Xtro\tmed6" "Mmus\Tmed1, Mmus\Tmed6, Mmus\Tmed5" "Hsap\TMED6, Hsap\TMED1, Hsap\TMED5" "viable,female sterile,recessive,lethal,partially lethal - majority die" FBgn0001977 CIAPIN1 Cytokine induced apoptosis inhibitor 1 http://flybase.org/reports/FBgn0001977 "FBgn0015867, FBgn0027853, FBgn0032560" protein_coding_gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR007785 molecular_function ; GO:0003674 | no biological data available negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with MGI:MGI:1922083 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype iron-sulfur cluster assembly ; GO:0016226 | inferred from biological aspect of ancestor with PANTHER:PTN000328118 sleep ; GO:0030431 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000328118 "BG:DS00929.9, anon-35Ba, l(2)br26, B, br26, D1, CG4180, CIAPIN1, D-CIAPIN1, l(2)35Bg" IPR007785:Anamorsin CG4180 11-Aug-17 DroID_v2017_08 Drer\ciapin1 Scer\DRE2 Cele\T20B12.7 Xtro\ciapin1 Mmus\Ciapin1 Hsap\CIAPIN1 "lethal,recessive,viable,female sterile,male sterile,mitotic cell cycle defective,increased cell death,lethal - all die during second instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,partially lethal - majority die" "ovary,follicle cell" FBgn0043063 Tl::Toll-4 Tl::Toll-4 http://flybase.org/reports/FBgn0043063 engineered_fusion_gene - - - Tl::Toll-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262823 hemo hemotin http://flybase.org/reports/FBgn0262823 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P29310 phagocytosis ; GO:0006909 | inferred from mutant phenotype positive regulation of phagocytosis ; GO:0050766 | inferred from mutant phenotype positive regulation of defense response to bacterium ; GO:1900426 | inferred from mutant phenotype positive regulation of endosome organization ; GO:1904980 | inferred from mutant phenotype early endosome membrane ; GO:0031901 | inferred from direct assay "hemo, CG43194" - CG43194 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038009 CG17738 - http://flybase.org/reports/FBgn0038009 protein_coding_gene - - - CG17738 - CG17738 11-Aug-17 DroID_v2017_08 - - "Cele\fipr-23, Cele\C37A5.6, Cele\C18D11.6, Cele\C18D11.10, Cele\fipr-24, Cele\C18D11.9, Cele\fipr-22, Cele\C37A5.5, Cele\cnc-6, Cele\C37A5.3" - - - viable FBgn0022249 l(2)k01301 lethal (2) k01301 http://flybase.net/reports/FBgn0022249.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0011945 tRNA:Pro-TGG-1-2 transfer RNA:Proline-TGG 1-2 http://flybase.org/reports/FBgn0011945 "FBgn0003819, FBgn0051571, FBgn0060114" tRNA_gene CCA codon-amino acid adaptor activity ; GO:0033423 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033423 cytosol ; GO:0005829 | inferred by curator from GO:0033423 "Pro, AE002708.trna11-ProTGG, tRNA:P:TGG:AE002708-a, tRNA:pro:90Cb, CR31571, tRNA:Pro, chr3R.trna17-ProTGG, tRNA-Pro-TGG-1-2, tRNA:Pro-TGG-1-2, tRNA:P:90Cb, CCA" - CR31571 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032785 CG10026 - http://flybase.org/reports/FBgn0032785 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 sleep ; GO:0030431 | inferred from expression pattern intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 CG10026 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG10026 11-Aug-17 DroID_v2017_08 "Drer\ttpa, Drer\clvs2, Drer\ttpal, Drer\sec14l7, Drer\sec14l8, Drer\rlbp1a" "Scer\YKL091C, Scer\SEC14, Scer\SFH5" - "Xtro\sec14l3, Xtro\ttpal, Xtro\clvs1, Xtro\sec14l5, Xtro\mospd2, Xtro\sec14l1, Xtro\ttpa, Xtro\clvs2, Xtro\rlbp1" "Mmus\Clvs1, Mmus\Sec14l4, Mmus\Clvs2, Mmus\Ttpal, Mmus\Ttpa, Mmus\Sec14l1, Mmus\Sec14l2, Mmus\Rlbp1, Mmus\Sec14l5, Mmus\Sec14l3" "Hsap\RLBP1, Hsap\SEC14L2, Hsap\CLVS2, Hsap\SEC14L1, Hsap\SEC14L3, Hsap\SEC14L5, Hsap\SEC14L6, Hsap\TTPAL, Hsap\TTPA, Hsap\SEC14L4, Hsap\CLVS1" "viable,fertile" FBgn0010135 mat(2)N maternal lethal (2) Notchlike http://flybase.org/reports/FBgn0010135 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)31Ei, mat(2)N" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0001036 fs(3)G3 female sterile (3) G3 http://flybase.org/reports/FBgn0001036 - gene - - - "fs(3)3, fs(3)G3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male fertile" egg chamber FBgn0028607 l(2)W18 lethal (2) W18 http://flybase.org/reports/FBgn0028607 gene - - - "l(2R)W18, l(2)W18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015257 M1-52 M1-52 http://flybase.org/reports/FBgn0015257 - gene - - - M1-52 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039485 CG17189 - http://flybase.org/reports/FBgn0039485 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CG17189, cg17189" IPR010562:Haemolymph juvenile hormone binding CG17189 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037108 CG11306 - http://flybase.org/reports/FBgn0037108 protein_coding_gene "GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity ; GO:0004377 | inferred from biological aspect of ancestor with PANTHER:PTN000282401" neurogenesis ; GO:0022008 | inferred from mutant phenotype protein glycosylation in endoplasmic reticulum ; GO:0033577 | inferred from biological aspect of ancestor with PANTHER:PTN001394375 oligosaccharide-lipid intermediate biosynthetic process ; GO:0006490 | inferred from biological aspect of ancestor with PANTHER:PTN001394375 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN001394375 "CG11306, Alg11, dAlg11" "IPR001296:Glycosyl transferase, family 1, IPR031814:ALG11 mannosyltransferase, N-terminal" CG11306 11-Aug-17 DroID_v2017_08 Drer\alg11 Scer\ALG11 Cele\algn-11 Xtro\alg11 Mmus\Alg11 Hsap\ALG11 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0039464 CG6330 - http://flybase.org/reports/FBgn0039464 protein_coding_gene uridine phosphorylase activity ; GO:0004850 | inferred from electronic annotation with InterPro:IPR010059 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 nucleotide catabolic process ; GO:0009166 | inferred from electronic annotation with InterPro:IPR010059 sleep ; GO:0030431 | inferred from expression pattern gravitaxis ; GO:0042332 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010059 CG6330 "IPR000845:Nucleoside phosphorylase domain, IPR010059:Uridine phosphorylase, eukaryotic" CG6330 11-Aug-17 DroID_v2017_08 "Drer\upp1, Drer\upp2" - Cele\upp-1 "Xtro\upp1, Xtro\upp2" "Mmus\Upp2, Mmus\Upp1" "Hsap\UPP1, Hsap\UPP2" "viable,fertile,female fertile,lethal,gravitaxis defective" FBgn0085688 CG41557 - http://flybase.org/reports/FBgn0085688 protein_coding_gene - - - CG41557 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263657 CR43648 - http://flybase.org/reports/FBgn0263657 non_protein_coding_gene - - - CR43648 - CR43648 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067664 p80 p80 http://flybase.org/reports/FBgn0067664 gene - - - p80 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264873 CR44064 - http://flybase.org/reports/FBgn0264873 non_protein_coding_gene - - - CR44064 - CR44064 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004008 Washed-eye Washed eye http://flybase.org/reports/FBgn0004008 - gene - - - "Washed-eye, We" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable,fertile,eye color defective" eye FBgn0259992 CG42489 - http://flybase.org/reports/FBgn0259992 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42489 - CG42489 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040383 CG5254 - http://flybase.org/reports/FBgn0040383 protein_coding_gene dicarboxylic acid transmembrane transporter activity ; GO:0005310 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 autophagic cell death ; GO:0048102 | inferred from expression pattern dicarboxylic acid transport ; GO:0006835 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 "CT16777, EG:BACR19J1.2, CG5254" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG5254 11-Aug-17 DroID_v2017_08 Drer\slc25a21 "Scer\ODC1, Scer\ODC2" Cele\slc-25A21 Xtro\slc25a21 Mmus\Slc25a21 Hsap\SLC25A21 pupal stage salivary gland

viable FBgn0067388 c625 c625 http://flybase.org/reports/FBgn0067388 gene - - - c625 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0011625 l(2)T56i26 lethal (2) T56i26 http://flybase.org/reports/FBgn0011625 FBgn0005177 gene - - - l(2)T56i26 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038717 CG17751 - http://flybase.org/reports/FBgn0038717 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG17751 "IPR020846:Major facilitator superfamily domain, IPR011701:Major facilitator superfamily" CG17751 11-Aug-17 DroID_v2017_08 "Drer\slc22a5, Drer\slc22a21" "Scer\HXT2, Scer\GIT1, Scer\HXT9, Scer\HXT5, Scer\PHO84" "Cele\B0361.11, Cele\C53B4.1, Cele\B0252.3, Cele\Y57G11C.23, Cele\T22F7.1, Cele\ZK892.3, Cele\C06H5.6, Cele\Y51A2D.18, Cele\C46C2.2, Cele\oct-1, Cele\Y66D12A.13" - "Mmus\Slc22a5, Mmus\Slc22a28, Mmus\Slc22a21, Mmus\Slc22a4" "Hsap\SLC22A5, Hsap\SLC22A4, Hsap\SLC22A25" viable FBgn0011713 snowballs snowballs http://flybase.org/reports/FBgn0011713 - gene - - - "snb, snowballs" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "spermatid,meiosis & nuclear chromosome" FBgn0015560 upo unipolar disorder http://flybase.org/reports/FBgn0015560 FBgn0022149 gene - - - "uni, l(2)k05916, upo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037165 CG11437 - http://flybase.org/reports/FBgn0037165 protein_coding_gene phosphatidate phosphatase activity ; GO:0008195 | non-traceable author statement phosphatidate phosphatase activity ; GO:0008195 | inferred from sequence or structural similarity with SGD:S000002911 phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000017950 phospholipid metabolic process ; GO:0006644 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 phospholipid dephosphorylation ; GO:0046839 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 dephosphorylation ; GO:0016311 | non-traceable author statement phospholipid metabolic process ; GO:0006644 | inferred from sequence or structural similarity with SGD:S000002911 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 membrane ; GO:0016020 | inferred from sequence or structural similarity with SGD:S000002911 "WUN-like, CG11437, LPP-like" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG11437 11-Aug-17 DroID_v2017_08 "Drer\ppap2d, Drer\LOC794598, Drer\plppr2a, Drer\plpp4, Drer\plpp1a, Drer\plpp2a, Drer\plppr5a, Drer\plppr3a, Drer\plpp2b, Drer\plpp3, Drer\LOC571722, Drer\plppr2b, Drer\plpp5, Drer\plppr3b, Drer\plppr4a, Drer\plppr1" "Scer\LPP1, Scer\DPP1" "Cele\T28D9.3, Cele\T06D8.3" "Xtro\plpp1, Xtro\plpp3, Xtro\plppr5, Xtro\plppr3, Xtro\plpp5, Xtro\plpp4, Xtro\plpp2, Xtro\plppr4, Xtro\plppr2" "Mmus\Plpp2, Mmus\Plpp4, Mmus\Plppr4, Mmus\Plpp5, Mmus\Plppr3, Mmus\Plppr2, Mmus\Plpp3, Mmus\Plpp1, Mmus\Plppr5, Mmus\Plppr1" "Hsap\PLPPR3, Hsap\PLPP4, Hsap\PLPPR5, Hsap\PLPP3, Hsap\PLPPR1, Hsap\PLPPR4, Hsap\PLPPR2, Hsap\PLPP5, Hsap\PLPP2, Hsap\PLPP1" viable DRSC11659 IE 2.020201057 -0.014805558 2.136391485 1.142964818 -0.394853713 0.553634584 FBgn0060567 l(3)S096511 lethal (3) S096511 http://flybase.org/reports/FBgn0060567 gene - - - "0965/11, l(3)S096511" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028064 l(3)S092405 lethal (3) S092405 http://flybase.org/reports/FBgn0028064 gene - - - "0924/05, l(3)S092405" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036221 CG11588 - http://flybase.org/reports/FBgn0036221 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11588 - CG11588 11-Aug-17 DroID_v2017_08 "Drer\tmx4, Drer\tmx1" Scer\EPS1 Cele\dpy-11 "Xtro\tmx4, Xtro\tmx1" "Mmus\Tmx1, Mmus\Tmx4" "Hsap\TMX1, Hsap\TMX4" "viable,body color defective" mesothoracic tergum FBgn0032033 CG13392 - http://flybase.org/reports/FBgn0032033 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13392 IPR009801:Transmembrane protein 126 CG13392 11-Aug-17 DroID_v2017_08 Drer\tmem126a - - Xtro\tmem126a "Mmus\Tmem126a, Mmus\Tmem126b" "Hsap\TMEM126A, Hsap\TMEM126B" FBgn0005722 l(1)TK131 lethal (1) TK131 http://flybase.org/reports/FBgn0005722 - gene - - - "l131, l(1)TK131" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0004027 wtw water wings http://flybase.org/reports/FBgn0004027 - gene - - - "clf, wtw" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,reduced,male fertile,female fertile,female sterile" "eye,wing,male genitalia,adult abdomen,male,crossvein,female,posterior" FBgn0039728 CG7896 - http://flybase.org/reports/FBgn0039728 protein_coding_gene - - integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000757746 "CG7896, tartan/capricious-like, CT23878" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG7896 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-182i3.11, Drer\si:dkey-90m5.4, Drer\lrrc9, Drer\igfals, Drer\lrrc32, Drer\si:dkey-100n23.3" - "Cele\lron-15, Cele\C06A8.6" "Xtro\igfals, Xtro\lrrn4" "Mmus\Lrrn4, Mmus\Lrg1, Mmus\Igfals, Mmus\Lrrc32" "Hsap\IGFALS, Hsap\LRRC32, Hsap\LRRN4, Hsap\LRG1" "visible,partially lethal - majority die,some die during pupal stage,viable" mesothoracic tergum FBgn0267512 5.8SrRNA:CR45852 5.8S ribosomal RNA:CR45852 http://flybase.org/reports/FBgn0267512 rRNA_gene - - - "CR45852, 5.8SrRNA:CR45852" - CR45852 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035727 CG10063 - http://flybase.org/reports/FBgn0035727 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG10063, BcDNA:AT30027" - CG10063 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC09688 EK 0.551615388 0.239764117 0.158572023 1.543806654 1.760408554 0.496755182 FBgn0034062 CG8388 - http://flybase.org/reports/FBgn0034062 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG8388 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG8388 11-Aug-17 DroID_v2017_08 "Drer\prdm5, Drer\traf3, Drer\prdm10, Drer\xaf1, Drer\zgc:153116, Drer\trafd1, Drer\si:dkey-30k6.5" - "Cele\fezf-1, Cele\pag-3, Cele\hinf-1, Cele\ZK686.5" "Xtro\znf142, Xtro\prdm5, Xtro\traf6" "Mmus\Xaf1, Mmus\Prdm10, Mmus\Zfp280c, Mmus\Traf4, Mmus\Traf6, Mmus\Zfy2, Mmus\Zfy1" "Hsap\PRDM10, Hsap\XAF1, Hsap\ZNF544, Hsap\TRAF6, Hsap\ZNF280C, Hsap\PRDM5, Hsap\ZNF805" viable FBgn0051453 pch2 pachytene checkpoint 2 http://flybase.org/reports/FBgn0051453 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001270, InterPro:IPR003959, InterPro:IPR003960" meiotic recombination checkpoint ; GO:0051598 | inferred from mutant phenotype - "CG11744, CG11743, pch2, CG31453" "IPR001270:ClpA/B family, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG31453 11-Aug-17 DroID_v2017_08 Drer\trip13 Scer\PCH2 Cele\pch-2 Xtro\trip13 Mmus\Trip13 Hsap\TRIP13 "viable,female fertile" DRSC14368 K -0.347241951 -0.136049348 -0.535069892 -0.275983088 0.179490429 1.850368478 FBgn0051202 alpha-Man-Ic alpha-Mannosidase class I c http://flybase.org/reports/FBgn0051202 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001382 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from biological aspect of ancestor with PANTHER:PTN000201533" N-glycan processing ; GO:0006491 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000201534 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 "CG7880, CG31202, dMas-2, mas-2, alpha-Man-Ic" IPR001382:Glycoside hydrolase family 47 CG31202 11-Aug-17 DroID_v2017_08 "Drer\man1a2, Drer\man1a1" "Scer\MNS1, Scer\MNL2" "Cele\mans-2, Cele\mans-1" "Xtro\man1a1, Xtro\man1a2, Xtro\man1c1" "Mmus\Man1a2, Mmus\Man1c1, Mmus\Man1a" "Hsap\MAN1C1, Hsap\MAN1A2, Hsap\MAN1A1" viable FBgn0039759 CG9733 - http://flybase.org/reports/FBgn0039759 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG9733, SP10, c-SP10, proPO-AE, proAE" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG9733 11-Aug-17 DroID_v2017_08 Drer\st14b - - - - - "lethal,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0263953 BG00915 - http://flybase.org/reports/FBgn0263953 gene - - - BG00915 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective" FBgn0001682 l(1)ESHS3 lethal (1) ESHS3 http://flybase.org/reports/FBgn0001682 - gene - - - l(1)ESHS3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024539 l(3)L1910 lethal (3) L1910 http://flybase.org/reports/FBgn0024539 - gene - - - l(3)L1910 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050001 CG30001 - http://flybase.org/reports/FBgn0050001 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30001 "IPR031729:Fanconi anaemia group A protein, N-terminal domain" CG30001 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0086768 Pcmt Protein-L-isoaspartate (D-aspartate) O-methyltransferase http://flybase.org/reports/FBgn0086768 protein_coding_gene protein-L-isoaspartate (D-aspartate) O-methyltransferase activity ; GO:0004719 | inferred from direct assay cellular protein modification process ; GO:0006464 | inferred from electronic annotation with InterPro:IPR000682 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000171727 "CG2152, pcmt, Pcmt, dPIMT, PIMT, Pimt" "IPR000682:Protein-L-isoaspartate(D-aspartate) O-methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG2152 11-Aug-17 DroID_v2017_08 "Drer\LOC100536777, Drer\pcmtl, Drer\pcmt, Drer\pcmtd1, Drer\pcmtd2" - Cele\pcm-1 "Xtro\pcmtd2, Xtro\LOC100216173, Xtro\pcmt1" "Mmus\Pcmt1, Mmus\Pcmtd2, Mmus\Pcmtd1" "Hsap\PCMT1, Hsap\PCMTD2, Hsap\PCMTD1" FBgn0001038 Fs(3)Ger Female sterile (3) Gerec http://flybase.org/reports/FBgn0001038 - gene - - - "Ger, Fs(3)Gerec, Fs(3)Sz9, Fs(3)Ger" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "male pronucleus,female pronucleus" FBgn0023525 CG3191 - http://flybase.org/reports/FBgn0023525 "FBgn0040501, FBgn0042162" protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "EG:30B8.3, 62D9.a, BEST:GM01072, CG18842, CG3191" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG3191 11-Aug-17 DroID_v2017_08 "Drer\clvs2, Drer\rlbp1a, Drer\ttpal, Drer\sec14l8, Drer\ttpa, Drer\sec14l7, Drer\rlbp1b" "Scer\SEC14, Scer\YKL091C, Scer\SFH5" - "Xtro\clvs2, Xtro\rlbp1, Xtro\clvs1, Xtro\sec14l3, Xtro\sec14l1, Xtro\mospd2, Xtro\sec14l5, Xtro\ttpa, Xtro\ttpal" "Mmus\Sec14l5, Mmus\Rlbp1, Mmus\Ttpal, Mmus\Sec14l2, Mmus\Clvs2, Mmus\Sec14l4, Mmus\Sec14l3, Mmus\Ttpa, Mmus\Sec14l1, Mmus\Clvs1" "Hsap\SEC14L4, Hsap\SEC14L3, Hsap\TTPA, Hsap\RLBP1, Hsap\TTPAL, Hsap\CLVS1, Hsap\SEC14L2, Hsap\SEC14L6, Hsap\SEC14L1, Hsap\SEC14L5, Hsap\CLVS2" "viable,fertile" FBgn0003163 pubescent pubescent http://flybase.org/reports/FBgn0003163 - gene - - - "pub, pubescent" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,visible" "microchaeta,adult abdomen,male,leg,metathoracic leg,wing vein L5,wing" FBgn0043484 l(3)66EFb lethal (3) 66EFb http://flybase.org/reports/FBgn0043484 gene - - - l(3)66EFb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051822 CR31822 - http://flybase.org/reports/FBgn0051822 pseudogene_attribute - - - "CG31822, CR31822" - CR31822 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0002759 mit(1)9 mitotic 9 http://flybase.org/reports/FBgn0002759 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0034530 Rcd6 Reduction in Cnn dots 6 http://flybase.org/reports/FBgn0034530 protein_coding_gene molecular_function ; GO:0003674 | no biological data available centrosome organization ; GO:0051297 | inferred from mutant phenotype pericentriolar material ; GO:0000242 | inferred from direct assay "Rcd6, CG11175" - CG11175 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0040221 fs(2)AB00 fs(2)AB00 http://flybase.org/reports/FBgn0040221 gene - - - fs(2)AB00 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0264271 CR43771 - http://flybase.org/reports/FBgn0264271 non_protein_coding_gene - - - CR43771 - CR43771 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058075 CG40075 - http://flybase.org/reports/FBgn0058075 protein_coding_gene - - - CG40075 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032444 CCT4 Chaperonin containing TCP1 subunit 4 http://flybase.org/reports/FBgn0032444 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012717 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000143848 cytosol ; GO:0005829 | inferred from direct assay "CCT4, Tcp-1delta, Cct4, CG5525, Tcp1-delta, Q9VK69_DROME, TCP-1, TCP1-delta" "IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012717:T-complex protein 1, delta subunit, IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG5525 11-Aug-17 DroID_v2017_08 "Drer\fyco1a, Drer\cct5, Drer\cct4" Scer\CCT4 Cele\cct-4 "Xtro\cct4, Xtro\cct5" "Mmus\Cct4, Mmus\Fyco1, Mmus\Cct5" "Hsap\CCT4, Hsap\CCT5, Hsap\FYCO1" "lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,neuroblast | larval stage" DRSC02865 K -0.520511445 -0.324373587 0.09977478 -0.688622533 1.641948162 0.304121477 FBgn0033524 Cyp49a1 Cyp49a1 http://flybase.org/reports/FBgn0033524 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "49a1, Cyp49a1p, CG12894, CG18377, Cyp49a1, Cyp49A1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG18377 11-Aug-17 DroID_v2017_08 "Drer\cyp11c1, Drer\cyp27a7, Drer\cyp27a1.4, Drer\cyp27a1.2, Drer\cyp11a2, Drer\si:ch211-113j14.1, Drer\cyp24a1, Drer\si:dkey-91i10.3, Drer\cyp27c1, Drer\cyp27b1, Drer\zgc:136333" Scer\DIT2 "Cele\cyp-37B1, Cele\ZK177.4, Cele\cyp-44A1" "Xtro\cyp24a1, Xtro\LOC100145331, Xtro\cyp27c1, Xtro\LOC594905, Xtro\LOC100496109, Xtro\cyp27a1, Xtro\cyp27b1, Xtro\cyp11a1" "Mmus\Cyp27a1, Mmus\Cyp11a1, Mmus\Cyp27b1, Mmus\Cyp11b1, Mmus\Cyp11b2, Mmus\Cyp24a1" "Hsap\CYP11A1, Hsap\CYP27C1, Hsap\CYP27B1, Hsap\CYP24A1, Hsap\CYP11B1, Hsap\CYP11B2, Hsap\CYP27A1" FBgn0032634 Rpb11 Rpb11 http://flybase.org/reports/FBgn0032634 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR008193 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR009025 RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000358883 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000005365 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000005365 "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from biological aspect of ancestor with PANTHER:PTN000358883 DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000005365" "RPB11, CG6840, BcDNA:GM15177, Rpb11" "IPR008193:DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site, IPR009025:DNA-directed RNA polymerase, RBP11-like dimerisation domain" CG6840 11-Aug-17 DroID_v2017_08 Drer\polr2j Scer\RPB11 Cele\rpb-11 Xtro\polr2j Mmus\Polr2j "Hsap\POLR2J2, Hsap\POLR2J, Hsap\POLR2J3" lethal DRSC27111 K -0.403424413 -0.091395407 0.548895285 -0.309140762 1.069019604 1.81326517 FBgn0024997 CG2681 - http://flybase.org/reports/FBgn0024997 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR013010, InterPro:IPR013323 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10857" "multicellular organism development ; GO:0007275 | inferred from electronic annotation with InterPro:IPR004162, InterPro:IPR018121 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity with HGNC:10857" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR004162, InterPro:IPR018121 cellular_component ; GO:0005575 | no biological data available" "100G10.2, EG:100G10.2, CG2681" "IPR001841:Zinc finger, RING-type, IPR004162:E3 ubiquitin-protein ligase SIN-like, IPR008974:TRAF-like, IPR013010:Zinc finger, SIAH-type, IPR018121:Seven-in-absentia protein, TRAF-like domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2681 11-Aug-17 DroID_v2017_08 "Drer\cyhr1, Drer\siah1, Drer\siah2l" - Cele\siah-1 "Xtro\siah2, Xtro\siah1" "Mmus\6330408A02Rik, Mmus\Siah2, Mmus\Cyhr1, Mmus\Siah1b, Mmus\Siah1a, Mmus\Siah3" "Hsap\C19orf68, Hsap\SIAH2, Hsap\CYHR1, Hsap\SIAH1, Hsap\SIAH3" viable FBgn0003372 Sgs1 Salivary gland secretion 1 http://flybase.org/reports/FBgn0003372 - protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model - extracellular matrix ; GO:0031012 | inferred from sequence model "sgs1, sgs-1, Sgs, Sgs-1, CG3047, Sgs1, Muc25B" - CG3047 11-Aug-17 DroID_v2017_08 "Drer\scospondin, Drer\vwf, Drer\LOC799643, Drer\otogl, Drer\asic2" "Scer\FLO11, Scer\FLO5, Scer\FLO1, Scer\YMR317W, Scer\MSB2, Scer\FLO9, Scer\PRM7, Scer\HPF1, Scer\HKR1, Scer\FIG2, Scer\YIL169C" "Cele\dpy-6, Cele\clec-223, Cele\ZC178.2, Cele\srap-1, Cele\H43E16.1, Cele\H02F09.3" Xtro\prg4 "Mmus\Muc6, Mmus\Muc5b, Mmus\Gm9573, Mmus\Sspo, Mmus\Muc2, Mmus\Vwf, Mmus\Muc5ac, Mmus\Muc4" "Hsap\MUC17, Hsap\OTOG, Hsap\MUC19, Hsap\MUC2, Hsap\MUC6, Hsap\SSPO, Hsap\MUC5B, Hsap\MUC4, Hsap\VWF, Hsap\MUC16" larval stage | third instar larval salivary gland

larval stage | late third instar larval stage embryonic/larval salivary gland

"electrophoretic variant,viable" FBgn0084718 knk::Tsf2 knk::Tsf2 http://flybase.org/reports/FBgn0084718 engineered_fusion_gene - - - knk::Tsf2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016036 mei-P22 meiotic P22 http://flybase.org/reports/FBgn0016036 - protein_coding_gene - reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | traceable author statement nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay "MEI-P22, CG14827, mei-P22, Mei-P22" - CG14827 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,partially lethal - majority die" FBgn0029950 CG9657 - http://flybase.org/reports/FBgn0029950 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "CG9657, dSLC5A9, cg9657" IPR001734:Sodium/solute symporter CG9657 11-Aug-17 DroID_v2017_08 "Drer\slc5a3a, Drer\slc5a12, Drer\LOC568338, Drer\slc5a2, Drer\si:dkeyp-9d4.5, Drer\slc5a9, Drer\slc5a1, Drer\slc5a5, Drer\slc5a6a, Drer\slc5a8, Drer\slc5a11, Drer\slc5a8l, Drer\slc5a6b" Scer\DUR3 "Cele\F52H2.4, Cele\ZK822.5" "Xtro\slc5a2, Xtro\slc5a9, Xtro\slc5a1.1, Xtro\slc5a8, Xtro\slc5a11, Xtro\slc5a12, Xtro\slc5a5" "Mmus\Slc5a3, Mmus\Slc5a4a, Mmus\Slc5a4b, Mmus\Slc5a1, Mmus\Slc5a10, Mmus\Slc5a2, Mmus\Slc5a8, Mmus\Slc5a12, Mmus\Slc5a11, Mmus\Slc5a5, Mmus\Slc5a6, Mmus\Gm5134, Mmus\Slc5a9" "Hsap\SLC5A1, Hsap\SLC5A3, Hsap\SLC5A10, Hsap\SLC5A11, Hsap\SLC5A9, Hsap\SLC5A12, Hsap\SLC5A4, Hsap\SLC5A2, Hsap\SLC5A8, Hsap\SLC5A6, Hsap\SLC5A5" viable FBgn0032264 Lip4 Lipase 4 http://flybase.org/reports/FBgn0032264 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" - - "CG6113, Lip4, dLip4, dlip4, lip4" "IPR025483:Lipase, eukaryotic, IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG6113 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\TGL1, Scer\YEH2, Scer\YEH1" "Cele\lipl-8, Cele\lipl-2, Cele\lipl-7, Cele\lipl-4, Cele\lipl-5, Cele\lipl-1, Cele\lipl-3, Cele\lipl-6" Xtro\lipa "Mmus\Lipo3, Mmus\Lipm, Mmus\Lipn, Mmus\Lipf, Mmus\Lipo4, Mmus\Lipo1, Mmus\Lipk, Mmus\Lipo2, Mmus\Lipa" "Hsap\LIPA, Hsap\LIPJ, Hsap\LIPF, Hsap\LIPM, Hsap\LIPN, Hsap\LIPK" "viable,fertile" FBgn0266782 CR45247 - http://flybase.org/reports/FBgn0266782 non_protein_coding_gene - - - CR45247 - CR45247 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029179 E(Khc)ek8 E(Khc)ek8 http://flybase.org/reports/FBgn0029179 gene - - - E(Khc)ek8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250824 CG33655 - http://flybase.org/reports/FBgn0250824 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT03788, NEST:bs30e09, CG33655, CR33655" - CG33655 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003105 PL(3)sp-W2 Polygenic locus sternopleural W2 http://flybase.org/reports/FBgn0003105 - gene - - - "b, PL(3)sp[W2], PL(3)sp-W2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033392 CG8027 - http://flybase.org/reports/FBgn0033392 protein_coding_gene "transferase activity, transferring phosphorus-containing groups ; GO:0016772 | inferred from electronic annotation with InterPro:IPR021520" - - "CG8027, Cg8027" "IPR000800:Notch domain, IPR021520:Stealth protein CR2, conserved region 2, IPR031358:Stealth protein CR1, conserved region 1, IPR031357:Stealth protein CR3, conserved region 3, IPR031356:Stealth protein CR4, conserved region 4" CG8027 11-Aug-17 DroID_v2017_08 Drer\gnptab - "Cele\dex-1, Cele\BE10.3, Cele\C05D12.3, Cele\C05D12.2, Cele\C05E4.15" - Mmus\Gnptab Hsap\GNPTAB viable FBgn0002730 mfs(3)73A male female sterile 73A http://flybase.org/reports/FBgn0002730 - gene - - - mfs(3)73A - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile" FBgn0265587 CR44414 - http://flybase.org/reports/FBgn0265587 non_protein_coding_gene - - - "CR44414, lincRNA.81" - CR44414 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032457 CG15483 - http://flybase.org/reports/FBgn0032457 protein_coding_gene - - - "CG15483, dibeta3GnT3" - CG15483 11-Aug-17 DroID_v2017_08 "Drer\b4gat1, Drer\gxylt2, Drer\gxylt1b, Drer\gyltl1b, Drer\xxylt1, Drer\large, Drer\gxylt1a" - "Cele\bgnt-1.2, Cele\bgnt-1.5, Cele\bgnt-1.3, Cele\bgnt-1.1, Cele\bgnt-1.7, Cele\bgnt-1.6, Cele\lge-1, Cele\bgnt-1.8, Cele\bgnt-1.4" "Xtro\xxylt1, Xtro\b4gat1, Xtro\gxylt1, Xtro\large, Xtro\gyltl1b, Xtro\gxylt2" "Mmus\Gxylt1, Mmus\Large2, Mmus\Gxylt2, Mmus\Large1, Mmus\Xxylt1, Mmus\B4gat1" "Hsap\B4GAT1, Hsap\XXYLT1, Hsap\GXYLT1, Hsap\LARGE2, Hsap\LARGE1, Hsap\GXYLT2" viable FBgn0029102 anon-56Da anon-56Da http://flybase.org/reports/FBgn0029102 gene - - - "EST B, anon-56Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263622 CR43631 - http://flybase.org/reports/FBgn0263622 non_protein_coding_gene - - - CR43631 - CR43631 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263527 mir-4908 mir-4908 stem loop http://flybase.org/reports/FBgn0263527 miRNA_gene - - - "mir-4908, dme-mir-4908, CR43512" - CR43512 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000870 fs(1)M65 female sterile (1) M65 http://flybase.org/reports/FBgn0000870 - gene - - - fs(1)M65 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0267054 CR45498 - http://flybase.org/reports/FBgn0267054 pseudogene_attribute - - - CR45498 - CR45498 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050235 tRNA:Leu-AAG-1-3 transfer RNA:Leucine-AAG 1-3 http://flybase.org/reports/FBgn0050235 tRNA_gene CUU codon-amino acid adaptor activity ; GO:0033417 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033417 cytosol ; GO:0005829 | inferred by curator from GO:0033417 "CR30235, AE002787.trna45-LeuAAG, tRNA:L:AAG:AE002787-c, chr2R.trna28-LeuAAG, tRNA-Leu-AAG-1-3, tRNA:Leu-AAG-1-3, tRNA:CR30235, CUU" - CR30235 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003113 pls palsied http://flybase.org/reports/FBgn0003113 - gene - - - pls - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,heat sensitive" FBgn0065226 l(2)SH2209 lethal (2) SH2209 http://flybase.org/reports/FBgn0065226 gene - - - "l(2)SH2209, l(2)SH2 2209" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044036 Mod(rst)D252 Mod(rst)D252 http://flybase.org/reports/FBgn0044036 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D252, Mod(rst)D252" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0062562 P25 P25 http://flybase.org/reports/FBgn0062562 gene - - - P25 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036596 CG13045 - http://flybase.org/reports/FBgn0036596 protein_coding_gene - - - CG13045 - CG13045 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037144 CG7458 - http://flybase.org/reports/FBgn0037144 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG7458 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG7458 11-Aug-17 DroID_v2017_08 "Drer\slc22a4, Drer\slc22a5, Drer\slc22a21" "Scer\PHO84, Scer\HXT5, Scer\GIT1, Scer\HXT9, Scer\HXT2" "Cele\Y51A2D.18, Cele\spin-4, Cele\oct-2, Cele\Y57G11C.23, Cele\Y66D12A.13, Cele\oct-1, Cele\C46C2.2, Cele\C53B4.1, Cele\ZK892.3" "Xtro\slc22a5, Xtro\slc22a4" "Mmus\Slc22a4, Mmus\Slc22a5, Mmus\Slc22a17, Mmus\Slc22a21" "Hsap\SLC22A5, Hsap\SLC22A4, Hsap\SLC22A17" "viable,fertile" FBgn0002657 mat(2)cell-F maternal effect cellularisation defect F http://flybase.org/reports/FBgn0002657 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "fs(2)QC13, mat(2)cellQC13, mat(2)cell-F" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0033737 Nup54 Nucleoporin 54kD http://flybase.org/reports/FBgn0033737 protein_coding_gene structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000313393 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with UniProtKB:P70582 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from mutant phenotype nucleocytoplasmic transport ; GO:0006913 | inferred from sequence or structural similarity with UniProtKB:P70582 NLS-bearing protein import into nucleus ; GO:0006607 | inferred from mutant phenotype protein targeting ; GO:0006605 | inferred from sequence or structural similarity with UniProtKB:P70582 nuclear pore organization ; GO:0006999 | inferred from biological aspect of ancestor with PANTHER:PTN000313393 protein targeting to nuclear inner membrane ; GO:0036228 | inferred from biological aspect of ancestor with PANTHER:PTN000313393 protein import into nucleus ; GO:0006606 | inferred from mutant phenotype nuclear pore central transport channel ; GO:0044613 | inferred from biological aspect of ancestor with PANTHER:PTN000313393 nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with UniProtKB:P70582 "CG8831, Nup54, nup54, Nup53" "IPR025712:Nucleoporin Nup54, alpha-helical domain, IPR024864:Nucleoporin Nup54/Nup57/Nup44" CG8831 11-Aug-17 DroID_v2017_08 Drer\nup54 Scer\NUP57 Cele\npp-1 Xtro\nup54 Mmus\Nup54 Hsap\NUP54 "female fertile,viable,visible" trichogen cell FBgn0266826 CR45288 - http://flybase.org/reports/FBgn0266826 non_protein_coding_gene - - - CR45288 - CR45288 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004173 Mst84Db Male-specific RNA 84Db http://flybase.org/reports/FBgn0004173 "FBgn0045209, FBgn0063353" protein_coding_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis ; GO:0007283 | inferred from genetic interaction with Mst84Da, Mst84Dc, Mst84Dd sperm axoneme assembly ; GO:0007288 | inferred from genetic interaction with Mst84Da, Mst84Dc, Mst84Dd" cellular_component ; GO:0005575 | no biological data available "bs22c06.y1, Mst, Mstprox, Mst ORF, Mst84, Mst87D, NEST:bs22c06, BcDNA:AT08471, mst(3)gl-2, CG17934, Mst84Db" - CG17934 11-Aug-17 DroID_v2017_08 - - - - Mmus\Krtap17-1 - "viable,visible" trichogen cell FBgn0028650 anon-55Eb anon-55Eb http://flybase.org/reports/FBgn0028650 gene - - - "B-1450, anon-55Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039439 TwdlK TweedleK http://flybase.org/reports/FBgn0039439 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlK, CG6460" IPR004145:Domain of unknown function DUF243 CG6460 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028368 l(1)10Ak lethal (1) 10Ak http://flybase.org/reports/FBgn0028368 gene - - - l(1)10Ak - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025173 l(2)38Dc lethal (2) 38Dc http://flybase.org/reports/FBgn0025173 - gene - - - l(2)38Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265531 CR44381 - http://flybase.org/reports/FBgn0265531 non_protein_coding_gene - - - CR44381 - CR44381 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058468 CR40468 - http://flybase.org/reports/FBgn0058468 non_protein_coding_gene - - - CR40468 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262069 EG79 - http://flybase.org/reports/FBgn0262069 gene - - - EG79 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034457 Ir56c Ionotropic receptor 56c http://flybase.org/reports/FBgn0034457 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir56c, DmelIR56c, CG15122, IR56c" - CG15122 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037288 CG14661 - http://flybase.org/reports/FBgn0037288 protein_coding_gene - - - "CT34439, CG14661" IPR010562:Haemolymph juvenile hormone binding CG14661 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013979 Har63 Har63 http://flybase.org/reports/FBgn0013979 - gene - - - "har63, Har63" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0022287 l(2)10333 lethal (2) 10333 http://flybase.net/reports/FBgn0022287.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0038020 GstD9 Glutathione S transferase D9 http://flybase.org/reports/FBgn0038020 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GstD9, DmGSTD9, CG10091, GSTD9, GST-D9, DmGstd9, gstD9, gstd9" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG10091 11-Aug-17 DroID_v2017_08 "Drer\eef1g, Drer\gstt1a, Drer\gstt2, Drer\gstr, Drer\mars, Drer\gstt1b, Drer\vars, Drer\eef1e1" "Scer\GTT2, Scer\URE2, Scer\CAM1, Scer\GTT1, Scer\TEF4, Scer\YGR201C" - "Xtro\eef1e1, Xtro\gstt1, Xtro\eef1g" "Mmus\Gstt4, Mmus\Vars, Mmus\Eef1e1, Mmus\Gstt2, Mmus\Gstt3, Mmus\Gstt1, Mmus\Mars, Mmus\Eef1g" "Hsap\VARS, Hsap\GSTT2, Hsap\GSTT1, Hsap\EEF1E1, Hsap\MARS, Hsap\EEF1G, Hsap\GSTT2B" viable FBgn0028114 l(3)S064316b lethal (3) S064316b http://flybase.org/reports/FBgn0028114 gene - - - "0643/16, l(3)S064316, l(3)S064316b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0034691 Synj Synaptojanin http://flybase.org/reports/FBgn0034691 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 inositol trisphosphate phosphatase activity ; GO:0046030 | non-traceable author statement inositol-polyphosphate 5-phosphatase activity ; GO:0004445 | inferred from direct assay phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from electronic annotation with InterPro:IPR000300 phototransduction ; GO:0007602 | inferred from mutant phenotype regulation of synapse structure or activity ; GO:0050803 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype dephosphorylation ; GO:0016311 | non-traceable author statement synaptic vesicle endocytosis ; GO:0048488 | traceable author statement maintenance of presynaptic active zone structure ; GO:0048790 | inferred from mutant phenotype vesicle membrane ; GO:0012506 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay "CG6562, Synj, IPP, synj" "IPR000300:Inositol polyphosphate-related phosphatase, IPR002013:SAC domain, IPR005135:Endonuclease/exonuclease/phosphatase, IPR015047:Domain of unknown function DUF1866, IPR000504:RNA recognition motif domain" CG6562 11-Aug-17 DroID_v2017_08 Drer\synj1 "Scer\INP51, Scer\INP53, Scer\INP52" Cele\unc-26 Xtro\synj1 "Mmus\Synj2, Mmus\Synj1" "Hsap\SYNJ2, Hsap\SYNJ1" "neuroanatomy defective,neurophysiology defective,viable,lethal,recessive,locomotor behavior defective,somatic clone,endocytosis defective" "photoreceptor & synaptic vesicle,neuromuscular junction & synaptic vesicleX58-7),NMJ bouton,supernumerary,presynaptic active zoneX58-7),dense body,bouton,synaptic vesicle | somatic clone" FBgn0016814 l(1)L17 lethal (1) L17 http://flybase.org/reports/FBgn0016814 - gene - - - "l(1)L17, L17" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060612 l(3)S090214 lethal (3) S090214 http://flybase.org/reports/FBgn0060612 gene - - - "0902/14, l(3)S090214" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026394 Or24a Odorant receptor 24a http://flybase.org/reports/FBgn0026394 FBgn0031586 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 olfactory receptor activity ; GO:0004984 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "CG11767, 24a, Or24D.1, DOR48, 24D.1, DOR24D.1, Or24a" "IPR004117:Olfactory receptor, insect" CG11767 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,viable" FBgn0267264 CR45700 - http://flybase.org/reports/FBgn0267264 non_protein_coding_gene - - - CR45700 - CR45700 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035400 CG11537 - http://flybase.org/reports/FBgn0035400 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701" CG11537 "IPR001958:Tetracycline resistance protein TetA/multidrug resistance protein MdtG, IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG11537 11-Aug-17 DroID_v2017_08 "Drer\LOC557306, Drer\slc46a3, Drer\si:ch211-262i1.4, Drer\hiat1b, Drer\si:ch211-87m7.2, Drer\hiat1a, Drer\si:dkey-5g14.1, Drer\zgc:174356" Scer\YJL163C "Cele\T25D3.4, Cele\Y71G12B.25" "Xtro\mfsd14b, Xtro\mfsd14a" "Mmus\Mfsd14b, Mmus\Slc46a1, Mmus\Mfsd14a, Mmus\Slc46a3" "Hsap\MFSD14B, Hsap\SLC46A1, Hsap\SLC46A3, Hsap\MFSD14A" viable FBgn0030802 DENR Density regulated protein http://flybase.org/reports/FBgn0030802 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000300443 mRNA binding ; GO:0003729 | inferred from direct assay ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000300443 IRES-dependent translational initiation ; GO:0002192 | inferred from biological aspect of ancestor with PANTHER:PTN000300443 positive regulation of insulin receptor signaling pathway ; GO:0046628 | inferred from mutant phenotype formation of translation preinitiation complex ; GO:0001731 | inferred from biological aspect of ancestor with PANTHER:PTN000300443 ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from mutant phenotype positive regulation of translational initiation ; GO:0045948 | inferred from mutant phenotype translation reinitiation ; GO:0002188 | inferred from direct assay positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from physical interaction with MCTS1 translation initiation complex ; GO:0070992 | inferred from biological aspect of ancestor with PANTHER:PTN000300443 ribosome ; GO:0005840 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN000300443 "DENR, CG9099" "IPR001950:SUI1 domain, IPR005873:Density-regulated protein DRP1, IPR005872:Archaeal/bacterial translation initiation factor SUI1" CG9099 11-Aug-17 DroID_v2017_08 Drer\denr Scer\TMA22 Cele\Y47D3A.21 Xtro\denr Mmus\Denr Hsap\DENR "viable,visible" trichogen cell DRSC20151 K -0.237522013 -0.636198994 0.046707445 0.261215173 2.1585028 0.34994798 FBgn0000600 E(var)88D Enhancer of variegation 88D http://flybase.org/reports/FBgn0000600 - gene - - - E(var)88D - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant,lethal,recessive" FBgn0264848 vih vihar http://flybase.org/reports/FBgn0264848 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin conjugating enzyme activity ; GO:0061631 | inferred from direct assay ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630584 positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from mutant phenotype exit from mitosis ; GO:0010458 | inferred from mutant phenotype positive regulation of cellular protein catabolic process ; GO:1903364 | inferred from mutant phenotype anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from direct assay ubiquitin ligase complex ; GO:0000151 | inferred from direct assay spindle pole centrosome ; GO:0031616 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 nucleus ; GO:0005634 | inferred from direct assay "CG10682, anon-WO0172774.56, anon-WO0172774.55, anon-WO0172774.54, vih, 1105/01, l(3)S110501, vihar, UbcH10" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG10682 11-Aug-17 DroID_v2017_08 "Drer\dnttip1, Drer\ube2c" Scer\UBC11 - Xtro\ube2c "Mmus\Ube2c, Mmus\Ube2u" "Hsap\UBE2U, Hsap\UBE2C" DRSC09778 IE 1.133838337 -2.147923797 2.834704331 -4.474777211 -0.99294062 -0.248790768 FBgn0020494 D59 D59 http://flybase.org/reports/FBgn0020494 - gene - - - D59 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022030 l(2)k08816 lethal (2) k08816 http://flybase.net/reports/FBgn0022030.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0267013 CR45457 - http://flybase.org/reports/FBgn0267013 non_protein_coding_gene - - - CR45457 - CR45457 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026014 UC119 UC119 http://flybase.org/reports/FBgn0026014 - gene - - - UC119 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic epidermis,embryonic head" FBgn0038744 CG4733 - http://flybase.org/reports/FBgn0038744 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG4733, PR72, PR-72, dPR72, PP2A-B'', PP2A like, dPP2A-PR72, B''" "IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain" CG4733 11-Aug-17 DroID_v2017_08 "Drer\ppp2r3b, Drer\ppp2r3c, Drer\ppp2r3a" - "Cele\T22D1.5, Cele\C06G1.5, Cele\C06G1.6" "Xtro\ppp2r3c, Xtro\ppp2r3b" "Mmus\Ppp2r3c, Mmus\Ppp2r3a, Mmus\Ppp2r3d" "Hsap\PPP2R3C, Hsap\PPP2R3B, Hsap\PPP2R3A" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0267239 CR45679 - http://flybase.org/reports/FBgn0267239 non_protein_coding_gene - - - CR45679 - CR45679 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085225 CG34196 - http://flybase.org/reports/FBgn0085225 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34196 - CG34196 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062617 Mod(var)1227 Mod(var)1227 http://flybase.org/reports/FBgn0062617 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1227, Mod(var)1227" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,partially lethal - majority die,recessive" FBgn0260312 GSd306 - http://flybase.org/reports/FBgn0260312 gene - - - GSd306 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058006 CG40006 - http://flybase.org/reports/FBgn0058006 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "BcDNA:RE68569, CG40006" IPR002159:CD36 family CG40006 11-Aug-17 DroID_v2017_08 "Drer\scarb1, Drer\cd36, Drer\LOC564077, Drer\scarb2" - "Cele\scav-5, Cele\scav-2, Cele\scav-1, Cele\scav-3" "Xtro\cd36, Xtro\scarb2, Xtro\scarb1" "Mmus\Scarb2, Mmus\Cd36, Mmus\Scarb1" "Hsap\CD36, Hsap\SCARB2, Hsap\SCARB1" FBgn0259966 Sfp51E Seminal fluid protein 51E http://flybase.org/reports/FBgn0259966 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 molecular_function ; GO:0003674 | no biological data available chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp51E, CG42476" IPR002557:Chitin binding domain CG42476 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061054 l(3)S023014b lethal (3) S023014b http://flybase.org/reports/FBgn0061054 gene - - - "0230/14, l(3)S023014b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0004737 l(3)85Dd lethal (3) 85Dd http://flybase.org/reports/FBgn0004737 - gene - - - l(3)85Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060305 l(3)S148801a lethal (3) S148801a http://flybase.org/reports/FBgn0060305 gene - - - "1488/01, l(3)S148801a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039788 Rpt6R Regulatory particle triple-A ATPase 6-related http://flybase.org/reports/FBgn0039788 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ATPase activity ; GO:0016887 | inferred from sequence model TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with Rpt6 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with Rpt6 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 microtubule associated complex ; GO:0005875 | inferred from direct assay" "Dm_Rpt6b, DmCG2241, CG2241, Rpt6R, Rpt6b, S8, Rpt6" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR029067:CDC48 domain 2-like" CG2241 11-Aug-17 DroID_v2017_08 "Drer\psmc2, Drer\psmc5, Drer\psmc6, Drer\wdr12" Scer\RPT6 "Cele\C10G11.8, Cele\F56F11.4, Cele\rpt-4, Cele\rpt-6" "Xtro\psmc6, Xtro\psmc2, Xtro\psmc5, Xtro\wdr12" "Mmus\Wdr12, Mmus\Psmc2, Mmus\Psmc6, Mmus\Psmc5, Mmus\Pex1" "Hsap\WDR12, Hsap\PSMC2, Hsap\PSMC5, Hsap\PSMC6" "visible,partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective" "mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell,trichogen cell" DRSC15431 I -0.730885546 1.693128669 -0.971746966 0.752329121 -0.172286694 0.562557341 FBgn0010340 140up upstream of RpII140 http://flybase.org/reports/FBgn0010340 FBgn0004843 protein_coding_gene - multicellular organism development ; GO:0007275 | inferred from mutant phenotype - "DmRP140-upstream, DmRP140up, l(3)Z6, l(3)88Ba, CG9852, 140up" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG9852 11-Aug-17 DroID_v2017_08 Drer\timmdc1 - Cele\Y38F2AR.3 - Mmus\Timmdc1 Hsap\TIMMDC1 adult stage "lethal,recessive,viable,visible" trichogen cell FBgn0025485 l(3)88Ad lethal (3) 88Ad http://flybase.org/reports/FBgn0025485 - gene - - - l(3)88Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085780 CR40976 - http://flybase.org/reports/FBgn0085780 rRNA_gene - - - CR40976 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023156 Su(mg)2-3 Suppressor of modifier of gypsy 2-3 http://flybase.org/reports/FBgn0023156 - gene - - - Su(mg)2-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024215 l(3)E2 lethal (3) E2 http://flybase.org/reports/FBgn0024215 - gene - - - l(3)E2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028034 l(3)S101712 lethal (3) S101712 http://flybase.org/reports/FBgn0028034 gene - - - "1017/12, l(3)S101712" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033062 Ars2 Arsenic resistance protein 2 http://flybase.org/reports/FBgn0033062 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1ZAW0 inferred from physical interaction with UniProtKB:Q9V3L6 inferred from physical interaction with UniProtKB:Q9V9V7 "negative regulation of viral genome replication ; GO:0045071 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype conversion of ds siRNA to ss siRNA involved in RNA interference ; GO:0033168 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype primary miRNA processing ; GO:0031053 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "anon-WO0118547.166, CG7843, Ars2" "IPR021933:Protein of unknown function DUF3546, IPR007042:Arsenite-resistance protein 2" CG7843 11-Aug-17 DroID_v2017_08 Drer\srrt - Cele\E01A2.2 Xtro\srrt Mmus\Srrt Hsap\SRRT "lethal,immune response defective,heat sensitive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,female fertile,recessive" "embryonic/larval neuroblast,mesothoracic tergum" FBgn0028422 GluRIID Glutamate receptor IID http://flybase.org/reports/FBgn0028422 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 ionotropic glutamate receptor activity ; GO:0004970 | inferred from mutant phenotype ionotropic glutamate receptor activity ; GO:0004970 | inferred by curator from GO:0008328 glutamate-gated calcium ion channel activity ; GO:0022849 | inferred from direct assay kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity "calcium ion transport ; GO:0006816 | inferred from direct assay rhythmic excitation ; GO:0043179 | inferred from mutant phenotype synaptic transmission, glutamatergic ; GO:0035249 | inferred by curator from GO:0007274,GO:0008328 neuromuscular synaptic transmission ; GO:0007274 | inferred from expression pattern regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype" muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay ionotropic glutamate receptor complex ; GO:0008328 | inferred from mutant phenotype "GluR-IID, GluRIID, brec, GluRIA, CT13538, DKaiR-IA, CG18039, Kai-RIA, DmelGluRIID, DGluRIID, KaiRIA, gluRIID, kaiRIA" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG18039 11-Aug-17 DroID_v2017_08 "Drer\gria2a, Drer\gria2b, Drer\gria1a, Drer\grik4, Drer\grik1a, Drer\si:ch211-251b21.1, Drer\LOC100331381, Drer\gria4b, Drer\grik5, Drer\LOC100334689, Drer\gria3b, Drer\grik1b, Drer\grik2, Drer\gria3a, Drer\si:dkey-183j2.10" - "Cele\glr-8, Cele\glr-6, Cele\glr-3, Cele\glr-4, Cele\glr-5" "Xtro\gria1, Xtro\gria3, Xtro\grik1, Xtro\grik5, Xtro\gria4, Xtro\grik4" "Mmus\Grik5, Mmus\Grik2, Mmus\Grik1, Mmus\Gria1, Mmus\Grik4, Mmus\Gria3, Mmus\Gria2, Mmus\Grik3, Mmus\Gria4" "Hsap\GRIK1, Hsap\GRIA3, Hsap\GRIA2, Hsap\GRIK2, Hsap\GRIA1, Hsap\GRIK3, Hsap\GRIK4, Hsap\GRIA4, Hsap\GRIK5" "paralytic,recessive,neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,partially,viable" "embryonic/larval neuromuscular junction,central nervous system & motor neuron,neuromuscular junction,NMJ bouton" FBgn0024244 drm drumstick http://flybase.org/reports/FBgn0024244 FBgn0031551 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V4Z9 "digestive tract development ; GO:0048565 | inferred from direct assay embryonic hindgut morphogenesis ; GO:0048619 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:P23803 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with UniProtKB:P23803 imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:P23803 foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with UniProtKB:P23803 embryonic foregut morphogenesis ; GO:0048617 | inferred from mutant phenotype" - "drum, CG10016, drm" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG10016 11-Aug-17 DroID_v2017_08 "Drer\zbtb32, Drer\prdm12a, Drer\osr1, Drer\osr2" Scer\TDA9 "Cele\odd-1, Cele\odd-2" "Xtro\osr2, Xtro\osr1" "Mmus\Osr1, Mmus\Osr2" "Hsap\OSR2, Hsap\OSR1" " larval stage | third instar , pupal stage " " ventral thoracic disc | restricted

, leg | restricted

" "lethal,recessive,visible,somatic clone" "embryonic hindgut,embryonic proventriculus,embryonic/larval proventriculus,embryonic/larval hindgut,embryonic large intestine,embryonic dorsal epidermis,keyhole structure,embryonic foregut,embryonic small intestine,leg & adult cuticle | somatic clone,eye disc,somatic clone,disc epithelium proper & dorsal mesothoracic disc | somatic clone,wing hinge primordium,scutellum" FBgn0014327 l(3)ry60 lethal (3) ry60 http://flybase.org/reports/FBgn0014327 - gene - - - l(3)ry60 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035896 CG6983 - http://flybase.org/reports/FBgn0035896 protein_coding_gene - - cytosol ; GO:0005829 | inferred from direct assay CG6983 IPR026794:Uncharacterised protein family UPF0687 CG6983 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-151p13.8, Drer\si:ch211-74f19.2" - - Xtro\c20orf27 Mmus\1700037H04Rik Hsap\C20orf27 viable FBgn0052202 CG32202 - http://flybase.org/reports/FBgn0052202 protein_coding_gene molecular_function ; GO:0003674 | no biological data available apoptotic process ; GO:0006915 | inferred from electronic annotation with InterPro:IPR033555 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13381, CG32202" IPR033555:TCF3 fusion partner CG32202 11-Aug-17 DroID_v2017_08 Drer\tfpt - - Xtro\tfpt Mmus\Tfpt Hsap\TFPT viable FBgn0011297 l(2)not lethal (2) neighbor of tid http://flybase.org/reports/FBgn0011297 - protein_coding_gene "transferase activity, transferring hexosyl groups ; GO:0016758 | inferred from electronic annotation with InterPro:IPR007873" - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007873 endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR007873 "CG4084, ntid, 1(2) not, cDNA 10F, l(2)not, dAlg3" "IPR007873:Glycosyltransferase, ALG3" CG4084 11-Aug-17 DroID_v2017_08 Drer\alg3 Scer\ALG3 Cele\K09E4.2 Xtro\alg3 Mmus\Alg3 Hsap\ALG3 embryonic stage && larval stage embryonic stage "viable,fertile" FBgn0020252 rubymine rubymine http://flybase.org/reports/FBgn0020252 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available rubymine - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015576 alpha-Est8 alpha-Esterase-8 http://flybase.org/reports/FBgn0015576 - protein_coding_gene - - - "alphaE8, aE8, I, CG1121, alpha-Est8, DmalphaE8, Est8" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG1121 11-Aug-17 DroID_v2017_08 "Drer\nlgn3a, Drer\ces3, Drer\nlgn1, Drer\nlgn2b, Drer\si:ch211-93f2.1, Drer\nlgn2a, Drer\cell, Drer\cel.1, Drer\nlgn4b, Drer\ces2, Drer\nlgn4a, Drer\nlgn3b" - "Cele\ges-1, Cele\T28C12.5, Cele\F15A8.6, Cele\T28C12.4, Cele\Y71H2AM.13, Cele\B0238.1" "Xtro\cel, Xtro\ces3, Xtro\nlgn4x, Xtro\LOC100494782, Xtro\ces2, Xtro\nlgn2, Xtro\nlgn3" "Mmus\Cel, Mmus\Nlgn1, Mmus\Nlgn2, Mmus\Ces1h, Mmus\Ces2e, Mmus\Ces5a, Mmus\Ces3a, Mmus\Ces1g, Mmus\Ces3b, Mmus\Ces2h, Mmus\Ces1e, Mmus\Ces2b, Mmus\Ces2f, Mmus\Ces1b, Mmus\Ces4a, Mmus\Ces2g, Mmus\Ces1d, Mmus\Ces2c, Mmus\Ces2a, Mmus\Ces1f, Mmus\Nlgn3, Mmus\Ces1c" "Hsap\CES3, Hsap\NLGN4X, Hsap\CES4A, Hsap\CES2, Hsap\NLGN2, Hsap\CES1, Hsap\NLGN1, Hsap\NLGN3, Hsap\CEL, Hsap\CES5A, Hsap\NLGN4Y" FBgn0003211 rbl reduced bristles http://flybase.org/reports/FBgn0003211 FBgn0003672 gene - - - "rdb, tbs, Ho, rbl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" macrochaeta FBgn0019867 anon-B5 anon-B5 http://flybase.org/reports/FBgn0019867 - gene - - - "B5, anon-B5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025645 CG3598 - http://flybase.org/reports/FBgn0025645 - protein_coding_gene - - - "EG:100G7.3, CG3598" - CG3598 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0024556 mEFTu1 mitochondrial translation elongation factor Tu 1 http://flybase.org/reports/FBgn0024556 FBgn0033847 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR004541, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000005713 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with UniProtKB:P49411 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with SGD:S000005713" translational elongation ; GO:0006414 | inferred from sequence or structural similarity with UniProtKB:P49411 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype translational elongation ; GO:0006414 | inferred from sequence or structural similarity with SGD:S000005713 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000005713 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P49411 "mtEF-Tu, CG6050, l(3)L4569, eftu-M, EfTuM, efTuM, mEFTu1" "IPR000795:Transcription factor, GTP-binding domain, IPR004160:Translation elongation factor EFTu/EF1A, C-terminal, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR004541:Translation elongation factor EFTu/EF1A, bacterial/organelle, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR005225:Small GTP-binding protein domain, IPR031157:Tr-type G domain, conserved site, IPR033720:Elongation factor Tu, domain 2" CG6050 11-Aug-17 DroID_v2017_08 Drer\tufm Scer\TUF1 "Cele\tufm-1, Cele\tufm-2" - Mmus\Tufm Hsap\TUFM "lethal,recessive" "digestive system,somatic muscle" DRSC29468 K 0.019710674 0.249627686 -0.178120308 0.290771474 -0.771654608 1.629753792 FBgn0267717 CR46050 - http://flybase.org/reports/FBgn0267717 non_protein_coding_gene - - - "CR46050, Mgn1719" - CR46050 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016828 l(1)MZ15 lethal (1) MZ15 http://flybase.org/reports/FBgn0016828 - gene - - - "l(1)MZ15, M15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028949 CG15254 - http://flybase.org/reports/FBgn0028949 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" - "BACcr44L22.2, BG:BACR44L22.2, CG15254" "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG15254 11-Aug-17 DroID_v2017_08 "Drer\npsnl, Drer\bmp1b, Drer\npsn, Drer\tnfaip6, Drer\he1b, Drer\mep1b, Drer\c6ast3, Drer\c6ast1, Drer\mep1a.2, Drer\LOC100003133, Drer\mep1a.1, Drer\bmp1a, Drer\LOC797085, Drer\he2, Drer\tll1, Drer\si:ch73-40a17.3, Drer\he1a, Drer\c6ast4" - "Cele\nas-7, Cele\nas-6, Cele\nas-14, Cele\Y19D10A.6, Cele\nas-8, Cele\nas-39, Cele\ZC116.3, Cele\nas-15, Cele\nas-4, Cele\nas-12, Cele\nas-13, Cele\nas-1, Cele\nas-2" "Xtro\mep1b, Xtro\accs, Xtro\mep1a, Xtro\tnfaip6, Xtro\cubn, Xtro\tll1, Xtro\LOC100492324, Xtro\uvs.2, Xtro\tll2, Xtro\LOC100489456, Xtro\bmp1" "Mmus\Astl, Mmus\Cubn, Mmus\Tll2, Mmus\Mep1a, Mmus\Bmp1, Mmus\Mep1b, Mmus\Tnfaip6, Mmus\Adgrg6, Mmus\Tll1" "Hsap\TLL1, Hsap\TLL2, Hsap\TNFAIP6, Hsap\ASTL, Hsap\ADGRG6, Hsap\MEP1B, Hsap\MEP1A, Hsap\BMP1, Hsap\CUBN" viable DRSC01870 E -0.509680804 -0.425045421 -1.701933071 0.453752207 0.28012236 0.379817054 FBgn0083148 S(smoDN)395 Suppressor of smoDN 395 http://flybase.org/reports/FBgn0083148 gene - - - S(smoDN)395 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050454 tRNA:Glu-CTC-2-1 transfer RNA:Glutamic acid-CTC 2-1 http://flybase.org/reports/FBgn0050454 tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "CR30454, AE002787.trna3-GluCTC, tRNA:E:CTC:AE002787-a, chr2R.trna61-GluCTC, tRNA:Glu-CTC-2-1, tRNA:CR30454, tRNA-Glu-CTC-2-1, GAG" - CR30454 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020370 TppII tripeptidyl-peptidase II http://flybase.org/reports/FBgn0020370 "FBgn0021861, FBgn0062227" protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR000209 exopeptidase activity ; GO:0008238 | inferred from direct assay tripeptidyl-peptidase activity ; GO:0008240 | inferred from direct assay protein homooligomerization ; GO:0051260 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement "TPPII, CG3991, TPP II, dTPP II, dTPPII, l(2)k14301, anon-WO0118547.127, TppII, TPP2" "IPR000209:Peptidase S8/S53 domain, IPR015500:Peptidase S8, subtilisin-related, IPR034051:Tripeptidyl-peptidase II domain, IPR022229:Peptidase S8A, tripeptidyl peptidase II, IPR022232:Peptidase S8A, tripeptidyl peptidase II, arthropoda, IPR022398:Peptidase S8, subtilisin, His-active site, IPR023828:Peptidase S8, subtilisin, Ser-active site" CG3991 11-Aug-17 DroID_v2017_08 Drer\si:ch73-244f7.4 - Cele\tpp-2 Xtro\tpp2 Mmus\Tpp2 Hsap\TPP2 "lethal,recessive,viable,visible" trichogen cell FBgn0014302 l(3)94Fa lethal (3) 94Fa http://flybase.org/reports/FBgn0014302 - gene - - - l(3)94Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" eye FBgn0065902 l(2)SH0199 lethal (2) SH0199 http://flybase.org/reports/FBgn0065902 gene - - - "l(2)SH0199, l(2)SH2 0199" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038765 CG4424 - http://flybase.org/reports/FBgn0038765 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG4424 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR022755:Zinc finger, double-stranded RNA binding" CG4424 11-Aug-17 DroID_v2017_08 "Drer\mynn, Drer\gzf1" Scer\ZAP1 Cele\klf-3 - "Mmus\Zfp787, Mmus\Zbtb16, Mmus\Zfp771, Mmus\Zfp239" "Hsap\ZBTB16, Hsap\ZNF787, Hsap\ZNF771" viable FBgn0015970 l(2)55Db lethal (2) 55Db http://flybase.org/reports/FBgn0015970 - gene - - - l(2)55Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023144 T:Khc-606 T:Khc-606 http://flybase.org/reports/FBgn0023144 - engineered_tag - - - "T:Khc-606, T:Khc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031428 CG9886 - http://flybase.org/reports/FBgn0031428 protein_coding_gene glycerate kinase activity ; GO:0008887 | inferred from sequence or structural similarity with UniProtKB:Q8IVS8 glycerate kinase activity ; GO:0008887 | inferred from biological aspect of ancestor with PANTHER:PTN000259988 glycerate kinase activity ; GO:0008887 | inferred from sequence or structural similarity with HGNC:24247 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:24247 protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000259988 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:Q8IVS8 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q8IVS8 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000259988 "CG9886, AAF51252" "IPR007835:MOFRL domain, IPR025286:MOFRL-associated domain" CG9886 11-Aug-17 DroID_v2017_08 Drer\glyctk - Cele\C13B9.2 Xtro\glyctk Mmus\Glyctk Hsap\GLYCTK viable FBgn0003264 Rnase1 Ribonuclease 1 http://flybase.org/reports/FBgn0003264 - gene - - - "Rnase1, Pacman" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035857 CG8006 - http://flybase.org/reports/FBgn0035857 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8006 - CG8006 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003537 Stp-1 Strapped on 1 http://flybase.org/reports/FBgn0003537 - gene - - - Stp-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing margin,male" FBgn0061519 blairy blairy http://flybase.org/reports/FBgn0061519 gene - - - blairy - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037589 Obp85a Odorant-binding protein 85a http://flybase.org/reports/FBgn0037589 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "CG11732, Obp85a, DmelObp85a" IPR006170:Pheromone/general odorant binding protein CG11732 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0062582 Mod(var)234 Mod(var)234 http://flybase.org/reports/FBgn0062582 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "234, Mod(var)234" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,lethal" FBgn0267808 CR46133 - http://flybase.org/reports/FBgn0267808 non_protein_coding_gene - - - CR46133 - CR46133 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085618 CG41328 - http://flybase.org/reports/FBgn0085618 protein_coding_gene - - - CG41328 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040010 CG17493 - http://flybase.org/reports/FBgn0040010 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity "CG17493, CG40016" "IPR011992:EF-hand domain pair, IPR002048:EF-hand domain, IPR018247:EF-Hand 1, calcium-binding site" CG17493 11-Aug-17 DroID_v2017_08 "Drer\cetn4, Drer\cetn2, Drer\cetn3" Scer\CDC31 Cele\R08D7.5 "Xtro\cetn1, Xtro\cetn4, Xtro\cetn3" "Mmus\Cetn2, Mmus\Cetn1, Mmus\Cetn3, Mmus\Cetn4" "Hsap\CETN2, Hsap\EFCAB2, Hsap\CETN1, Hsap\CETN3" viable FBgn0027781 Su(y)P31 Su(y)P31 http://flybase.org/reports/FBgn0027781 - gene - - - "Su(y)[P31], Su(y)P31" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020896 Su(osk)G28 Suppressor of oskar G28 http://flybase.org/reports/FBgn0020896 - gene - - - "G28, Su(osk)G28" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265654 CR44461 - http://flybase.org/reports/FBgn0265654 non_protein_coding_gene - - - "lincRNA.295, CR44461" - CR44461 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040106 lectin-21Cb lectin-21Cb http://flybase.org/reports/FBgn0040106 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - "AC004573b, AC 004573B, CG13686, lectin-21Cb" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG13686 11-Aug-17 DroID_v2017_08 "Drer\hbl3, Drer\clec3ba, Drer\colec11, Drer\hbl4, Drer\clec3bb, Drer\si:dkeyp-94g1.1, Drer\hbl2, Drer\hbl1, Drer\clec11a" - Cele\clec-149 Xtro\clec3b "Mmus\Cd209g, Mmus\Colec11, Mmus\Colec10, Mmus\Mbl1, Mmus\Sftpa1, Mmus\Sftpd, Mmus\Clec3b, Mmus\Clec11a, Mmus\Mbl2" "Hsap\SFTPA2, Hsap\CLEC3A, Hsap\SFTPA1, Hsap\CLEC11A, Hsap\MBL2, Hsap\SFTPD, Hsap\CLEC4A, Hsap\CLEC3B, Hsap\COLEC11, Hsap\COLEC10" viable FBgn0022300 l(1)L9.8 lethal (1) L9.8 http://flybase.org/reports/FBgn0022300 - gene - - - "L9.8, l(1)L9.8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011798 l(3)rI809 lethal (3) rI809 http://flybase.org/reports/FBgn0011798 - gene - - - l(3)rI809 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031738 CG9171 - http://flybase.org/reports/FBgn0031738 protein_coding_gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - "CG9171, dibeta3GnT2" - CG9171 11-Aug-17 DroID_v2017_08 "Drer\gxylt1b, Drer\gyltl1b, Drer\xxylt1, Drer\gxylt1a, Drer\gxylt2, Drer\large, Drer\b4gat1" - "Cele\bgnt-1.3, Cele\bgnt-1.6, Cele\bgnt-1.1, Cele\bgnt-1.8, Cele\bgnt-1.7, Cele\lge-1, Cele\bgnt-1.2, Cele\bgnt-1.5, Cele\bgnt-1.4" "Xtro\gxylt2, Xtro\large, Xtro\b4gat1, Xtro\xxylt1, Xtro\gxylt1, Xtro\gyltl1b" "Mmus\Gxylt1, Mmus\Xxylt1, Mmus\Large2, Mmus\B4gat1, Mmus\Large1, Mmus\Gxylt2" "Hsap\GXYLT1, Hsap\LARGE2, Hsap\LARGE1, Hsap\B4GAT1, Hsap\XXYLT1, Hsap\GXYLT2" "viable,body color defective,behavior defective,recessive,long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,fertile" mesothoracic tergum FBgn0005003 darkener-of-white-eosin darkener of white-eosin http://flybase.org/reports/FBgn0005003 - gene - - - "darkener-of-white-eosin, dark" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye FBgn0033515 Ir47a Ionotropic receptor 47a http://flybase.org/reports/FBgn0033515 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir47a, CG12900/CG34363, DmelIR47a, CG12900, IR47a" - CG12900 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005219 l(3)ET13 lethal Elaine Tasaka 13 http://flybase.org/reports/FBgn0005219 - gene - - - l(3)ET13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" FBgn0032084 CG13101 - http://flybase.org/reports/FBgn0032084 protein_coding_gene - - - CG13101 - CG13101 11-Aug-17 DroID_v2017_08 - - "Cele\C46E10.2, Cele\srd-56" - - - viable intersegmental nerve FBgn0265919 CR44708 - http://flybase.org/reports/FBgn0265919 non_protein_coding_gene - - - "lincRNA.1016, CR44708" - CR44708 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084008 CR41443 - http://flybase.org/reports/FBgn0084008 non_protein_coding_gene - - - "CG41443, chr2R_1141286_1142866.0, CR41443" - CR41443 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001872 l(1)XN52 lethal (1) XN52 http://flybase.org/reports/FBgn0001872 - gene - - - l(1)XN52 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265074 CR44185 - http://flybase.org/reports/FBgn0265074 non_protein_coding_gene - - - CR44185 - CR44185 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001781 l(1)M70 lethal (1) M70 http://flybase.org/reports/FBgn0001781 - gene - - - l(1)M70 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0259470 C705 - http://flybase.org/reports/FBgn0259470 gene - - - C705 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,chaeta" FBgn0086043 snoRNA:Me18S-C1024 - http://flybase.org/reports/FBgn0086043 snoRNA_gene - - - "snoRNA:Me18S-C1024, Me18S-Cm1024, CR34672" - CR34672 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038092 beat-Vb beat-Vb http://flybase.org/reports/FBgn0038092 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic - "beat Vb, CG14386, CG14385, CG31298, beat-Vb, Beat-Vb" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG31298 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-71p21.13, Drer\zgc:153911, Drer\LOC797620, Drer\zgc:172120, Drer\cd276" - - "Xtro\clmp, Xtro\esam" - "Hsap\F11R, Hsap\CADM2" "viable,fertile" DRSC12940 E 1.417581411 -0.120508528 1.443371841 1.828473614 0.042311771 -0.452172504 FBgn0005438 l(1)v75 lethal (1) v75 http://flybase.org/reports/FBgn0005438 - gene - - - "l(1)75, l(1)v75" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000852 fs(1)M41 female sterile (1) M41 http://flybase.org/reports/FBgn0000852 - gene - - - fs(1)M41 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,rescuable maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0011114 l(1)Q75 lethal (1) Q75 http://flybase.org/reports/FBgn0011114 FBgn0010210 gene - - - l(1)Q75 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085473 CG34444 - http://flybase.org/reports/FBgn0085473 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34444, CG30070" IPR006631:Protein of unknown function DM4/12 CG34444 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065156 l(3)SH050 lethal (3) SH050 http://flybase.org/reports/FBgn0065156 gene - - - "l(3)SH050, l(2)SH3 050" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050265 CG30265 - http://flybase.org/reports/FBgn0050265 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "CG11682, CG30265" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG30265 11-Aug-17 DroID_v2017_08 "Drer\slc17a8, Drer\ppt1, Drer\si:ch1073-513e17.1, Drer\slc17a9a, Drer\slc17a6a, Drer\slc17a6b, Drer\slc17a7a, Drer\slc17a5" "Scer\YIL166C, Scer\TNA1, Scer\THI73, Scer\DAL5" "Cele\D1046.4, Cele\H11E01.2, Cele\C35A5.3, Cele\F41C3.2, Cele\F11A5.9, Cele\F59A1.13, Cele\T02B11.6, Cele\slc-17.1, Cele\T19D12.9, Cele\Y4C6B.3, Cele\K08C7.1, Cele\eat-4, Cele\slc-17.2, Cele\Y4C6B.4, Cele\slc-17.3, Cele\slc-17.4, Cele\Y19D10A.11, Cele\F56A4.12, Cele\R10D12.1, Cele\T22F3.8, Cele\Y19D10A.5, Cele\T28H11.8, Cele\Y19D10A.4, Cele\T19D12.10, Cele\T01H3.3, Cele\Y19D10A.8, Cele\vglu-3, Cele\vglu-2, Cele\T22F3.7, Cele\C01B4.8, Cele\Y51B9A.6, Cele\F10C2.7, Cele\cima-1, Cele\F56A4.10, Cele\slc-17.9, Cele\slc-17.8, Cele\slc-17.5, Cele\C18D1.2, Cele\C39E9.7, Cele\T22F3.11, Cele\F44E7.7, Cele\K11G9.5, Cele\Y15E3A.4, Cele\T27D12.1, Cele\M162.5, Cele\W04C9.6, Cele\C18H9.5, Cele\C01B4.7, Cele\T22F3.10, Cele\M117.1" Xtro\slc17a7 "Mmus\Slc17a4, Mmus\Slc17a5, Mmus\Slc17a7, Mmus\Slc17a8, Mmus\Slc17a6, Mmus\Slc17a3, Mmus\Slc17a2, Mmus\Slc17a1" "Hsap\SLC17A7, Hsap\SLC17A5, Hsap\SLC17A2, Hsap\SLC17A6, Hsap\SLC17A8, Hsap\SLC17A3, Hsap\SLC17A1, Hsap\SLC17A4" "viable,fertile" FBgn0002243 l(3)68Ce lethal (3) 68Ce http://flybase.org/reports/FBgn0002243 - gene - - - "rsg4, l(3)rsg4, l(3)68Ce" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065613 l(2)SH0827 lethal (2) SH0827 http://flybase.org/reports/FBgn0065613 gene - - - "l(2)SH0827, l(2)SH2 0827" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065483 l(2)SH1275 lethal (2) SH1275 http://flybase.org/reports/FBgn0065483 gene - - - "l(2)SH1275, l(2)SH2 1275" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267636 CR45974 - http://flybase.org/reports/FBgn0267636 non_protein_coding_gene - - - CR45974 - CR45974 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061210 Egfr::htl Egfr::htl http://flybase.org/reports/FBgn0061210 engineered_fusion_gene - - - Egfr::htl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265813 CR44602 - http://flybase.org/reports/FBgn0265813 non_protein_coding_gene - - - "lincRNA.156, CR44602" - CR44602 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262528 CG43082 - http://flybase.org/reports/FBgn0262528 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43082 IPR003475:Insect protein of unknown function CG43082 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265144 CR44213 - http://flybase.org/reports/FBgn0265144 non_protein_coding_gene - - - CR44213 - CR44213 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002117 l(2)Co lethal (2) Corato http://flybase.org/reports/FBgn0002117 - gene - - - l(2)Co - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005259 l(3)SG79 lethal (3) SG79 http://flybase.org/reports/FBgn0005259 - gene - - - l(3)SG79 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0015979 l(2)PC4-E lethal (2) PC4-E http://flybase.org/reports/FBgn0015979 - gene - - - "l(2)PC4-H, l(2)PC4-E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058177 CG40177 - http://flybase.org/reports/FBgn0058177 protein_coding_gene - - - CG40177 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035337 CG15877 - http://flybase.org/reports/FBgn0035337 protein_coding_gene - - - CG15877 IPR019327:Protein of unknown function DUF2373 CG15877 11-Aug-17 DroID_v2017_08 Drer\c24h7orf50 Scer\YCR016W - - Mmus\3110082I17Rik Hsap\C7orf50 viable FBgn0262773 Su(E1)-G - http://flybase.org/reports/FBgn0262773 gene - - - Su(E1)-G - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040049 CG17427 - http://flybase.org/reports/FBgn0040049 protein_coding_gene - - - CG17427 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004819 fs(2)ltoDG25 female sterile (2) ltoDG25 http://flybase.org/reports/FBgn0004819 - gene molecular_function ; GO:0003674 | no biological data available ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "DG25, fs(2)ltoDG25" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0085442 NKAIN "Na,K-ATPase Interacting" http://flybase.org/reports/FBgn0085442 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24046 regulation of sodium ion transport ; GO:0002028 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG32836, anon-WO0118547.94, CG9047, NKAIN, CG34413, dNKAIN" "IPR008516:Na,K-Atpase Interacting protein" CG34413 11-Aug-17 DroID_v2017_08 "Drer\zgc:100920, Drer\nkain1, Drer\nkain4" - Cele\T13H5.6 "Xtro\nkain1, Xtro\nkain4, Xtro\nkain3" "Mmus\Nkain4, Mmus\Nkain3, Mmus\Nkain1, Mmus\Nkain2" "Hsap\NKAIN1, Hsap\NKAIN2, Hsap\NKAIN3, Hsap\NKAIN4" FBgn0260291 GSd408 - http://flybase.org/reports/FBgn0260291 gene - - - GSd408 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060595 l(3)S092016b lethal (3) S092016b http://flybase.org/reports/FBgn0060595 gene - - - "0920/16, l(3)S092016b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065198 l(2)SH2315 lethal (2) SH2315 http://flybase.org/reports/FBgn0065198 gene - - - "l(2)SH2315, l(2)SH2 2315" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086288 GS2285 - http://flybase.org/reports/FBgn0086288 gene - - - "GS2285, 2285" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060352 l(3)S141914 lethal (3) S141914 http://flybase.org/reports/FBgn0060352 gene - - - "1419/14, l(3)S141914" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0021978 l(2)k09920 lethal (2) k09920 http://flybase.net/reports/FBgn0021978.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0266655 CR45162 - http://flybase.org/reports/FBgn0266655 non_protein_coding_gene - - - CR45162 - CR45162 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039618 CG14520 - http://flybase.org/reports/FBgn0039618 protein_coding_gene - - - CG14520 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038927 CG6015 - http://flybase.org/reports/FBgn0038927 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:17350 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002772 inferred from sequence or structural similarity with protein_id:AAC39730 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000002772 inferred from sequence or structural similarity with protein_id:AAC39730 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG6015, CDC40, prp17" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032847:Pre-mRNA-processing factor 17, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG6015 11-Aug-17 DroID_v2017_08 Drer\cdc40 Scer\CDC40 "Cele\Y54G2A.12, Cele\prp-17" Xtro\cdc40 Mmus\Cdc40 Hsap\CDC40 "neuroanatomy defective,lethal" "presumptive embryonic/larval peripheral nervous system,ventral midline neuron & axon,longitudinal connective,ventral nerve cord commissure,ventral nerve cord" DRSC15948 IE 0.647497706 3.656099761 1.925479591 -0.30404324 -1.266909177 1.150248943 FBgn0038980 Octbeta1R Octopamine beta1 receptor http://flybase.org/reports/FBgn0038980 protein_coding_gene adrenergic receptor activity ; GO:0004935 | inferred from electronic annotation with InterPro:IPR002233 octopamine receptor activity ; GO:0004989 | inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | inferred from direct assay adenylate cyclase-activating G-protein coupled receptor signaling pathway ; GO:0007189 | inferred from direct assay positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010579 | inferred from direct assay positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway ; GO:0051482 | NOT inferred from direct assay negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0004989 "Octbeta1R, CG6919, DmOctBeta1R, Dmoa2, DmCG6919, anon-WO0170980.68, anon-WO0170980.67, OctBeta1, Oa2, OA2, oa2, DmOctbeta1R, octbeta1R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR002233:Adrenoceptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG6919 11-Aug-17 DroID_v2017_08 "Drer\taar13b, Drer\taar12g, Drer\taar19e, Drer\taar20x, Drer\taar20w, Drer\drd7, Drer\htr4, Drer\taar12m, Drer\si:dkey-246e3.4, Drer\taar12a, Drer\taar14f, Drer\taar18g, Drer\taar19d, Drer\si:ch211-238p8.35, Drer\taar14e, Drer\LOC567498, Drer\taar20b, Drer\taar19b, Drer\taar10b, Drer\LOC100149223, Drer\taar16f, Drer\taar14j, Drer\taar20n, Drer\taar12i, Drer\taar19p, Drer\taar12e, Drer\taar18e, Drer\taar20c1, Drer\taar19r, Drer\taar20h, Drer\taar20u, Drer\zgc:153137, Drer\taar20q, Drer\si:dkey-247m21.3, Drer\taar13c, Drer\taar14i, Drer\taar14l, Drer\taar10c, Drer\taar20r, Drer\taar18b, Drer\taar20o, Drer\taar20j, Drer\or103-5, Drer\taar11, Drer\or103-2, Drer\si:ch211-139n6.11, Drer\taar64, Drer\taar19o, Drer\taar12f, Drer\taar18c, Drer\taar12c, Drer\taar12b, Drer\taar14a, Drer\taar10, Drer\taar12j, Drer\taar18a, Drer\taar20c, Drer\taar20t, Drer\adrb3b, Drer\taar14g, Drer\taar13d, Drer\LOC563567, Drer\taar19c, Drer\drd1a, Drer\taar14d, Drer\taar10d, Drer\taar20a, Drer\taar10a, Drer\taar15, Drer\taar13e, Drer\taar19m, Drer\drd6b, Drer\taar20l, Drer\taar20i, Drer\adra1ab, Drer\taar1b, Drer\taar12h, Drer\taar19g, Drer\taar19k, Drer\drd1b, Drer\taar14h, Drer\taar14b" - "Cele\dop-1, Cele\ser-7, Cele\ser-5, Cele\F59D12.1, Cele\C01F1.4" "Xtro\drd5, Xtro\drd1, Xtro\htr4, Xtro\drd1c" "Mmus\Taar8c, Mmus\Taar1, Mmus\Drd5, Mmus\Taar6, Mmus\Taar5, Mmus\Taar7f, Mmus\Olfr1318, Mmus\Htr4, Mmus\Taar8a, Mmus\Taar4, Mmus\Adrb3, Mmus\Adrb1, Mmus\Taar7e, Mmus\Taar8b, Mmus\Taar9, Mmus\Taar2, Mmus\Drd1, Mmus\Taar7a, Mmus\Taar7b, Mmus\Taar7d, Mmus\Taar3" "Hsap\TAAR9, Hsap\TAAR6, Hsap\ADRB1, Hsap\TAAR5, Hsap\TAAR2, Hsap\TAAR8, Hsap\TAAR1, Hsap\DRD1, Hsap\ADRB3, Hsap\HTR4, Hsap\DRD5" "viable,fertile,neuroanatomy defective,locomotor behavior defective" "embryonic/larval neuromuscular junction | third instar larval stage,type II bouton,supernumerary | third instar larval stage,type I bouton,embryonic/larval neuromuscular junction,supernumerary" FBgn0015355 anon-99Cd anon-99Cd http://flybase.org/reports/FBgn0015355 - gene - - - anon-99Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001581 l(1)AL3 lethal (1) AL3 http://flybase.org/reports/FBgn0001581 - gene - - - l(1)AL3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,short lived" FBgn0052987 CG32987 - http://flybase.org/reports/FBgn0052987 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15866, CG32987" - CG32987 11-Aug-17 DroID_v2017_08 - - Cele\ZC13.2 - - - DRSC22373 IK 0.550298323 -1.502227948 -0.240381416 0.311011642 0.729869589 1.800283973 FBgn0085507 CG40660 - http://flybase.org/reports/FBgn0085507 protein_coding_gene - - - CG40660 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019840 ato::sc ato::sc http://flybase.org/reports/FBgn0019840 - engineered_fusion_gene - - - ato::sc - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "chordotonal organ of wing,ectopic,wing & external sensory organhs.PB,external sensory organ" FBgn0060406 l(3)S130610 lethal (3) S130610 http://flybase.org/reports/FBgn0060406 gene - - - "1306/10, l(3)S130610" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0029951 CG11369 - http://flybase.org/reports/FBgn0029951 protein_coding_gene - - - CG11369 - CG11369 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260430 CG42525 - http://flybase.org/reports/FBgn0260430 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG42525 "IPR009030:Growth factor receptor cysteine-rich domain, IPR002557:Chitin binding domain" CG42525 11-Aug-17 DroID_v2017_08 - Scer\DSE2 - - Mmus\1810055G02Rik - FBgn0022721 sour-grapes sour grapes http://flybase.org/reports/FBgn0022721 - gene - - - sour-grapes - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030412 Tomosyn Tomosyn http://flybase.org/reports/FBgn0030412 protein_coding_gene syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000028271 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000028271 SNARE binding ; GO:0000149 | inferred from sequence or structural similarity with SGD:S000006236 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000028271 establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of protein secretion ; GO:0050708 | inferred from biological aspect of ancestor with PANTHER:PTN000028273 synaptic vesicle priming ; GO:0016082 | non-traceable author statement regulation of exocytosis ; GO:0017157 | inferred from biological aspect of ancestor with PANTHER:PTN000028271 exocytosis ; GO:0006887 | inferred from sequence or structural similarity with SGD:S000006236 Golgi to plasma membrane transport ; GO:0006893 | inferred from sequence or structural similarity with SGD:S000006236 regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement long-term memory ; GO:0007616 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001388 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000028271 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000028271 synaptic vesicle ; GO:0008021 | non-traceable author statement neuromuscular junction ; GO:0031594 | inferred from direct assay "CG2205, CG17762, CG11056, Tomosyn, BcDNA:RH19475, tomosyn" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000664:Lethal(2) giant larvae protein, IPR001388:Synaptobrevin, IPR001680:WD40 repeat, IPR013577:Lethal giant larvae homologue 2, IPR019775:WD40 repeat, conserved site" CG17762 11-Aug-17 DroID_v2017_08 "Drer\stxbp5l, Drer\llgl2, Drer\stxbp6l, Drer\stxbp5a, Drer\stxbp5b, Drer\llgl1" "Scer\SRO77, Scer\SRO7" Cele\tom-1 "Xtro\stxbp6, Xtro\llgl2, Xtro\llgl1, Xtro\stxbp5" "Mmus\Llgl1, Mmus\Stxbp5l, Mmus\Llgl2, Mmus\Stxbp5" "Hsap\LLGL1, Hsap\STXBP5L, Hsap\LLGL2, Hsap\STXBP5" "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage,neurophysiology defective,memory defective" "embryonic/larval hemocyte | third instar larval stage,embryonic/larval neuroblast,ganglion mother cell,intersegmental nerve,anterior fascicle & synapse" FBgn0083021 snoRNA:Psi18S-640f snoRNA:Psi18S-640f http://flybase.org/reports/FBgn0083021 snoRNA_gene - - - "snoRNA:Psi18S-640f, psi18s-640f, CR34583" - CR34583 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267671 CR46007 - http://flybase.org/reports/FBgn0267671 non_protein_coding_gene - - - CR46007 - CR46007 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0008652 mei-S82 meiotic from via Salaria 82 http://flybase.org/reports/FBgn0008652 - gene molecular_function ; GO:0003674 | no biological data available female meiotic division ; GO:0007143 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mei-S82 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,meiotic cell cycle defective,female" FBgn0040088 p110 p110 http://flybase.org/reports/FBgn0040088 gene - - - p110 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266998 alpha-Cat::baz - http://flybase.org/reports/FBgn0266998 engineered_fusion_gene - - - "Baz::alphaCat, alpha-Cat::baz" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000894 fs(1)M94 female sterile (1) M94 http://flybase.org/reports/FBgn0000894 - gene - - - fs(1)M94 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0026303 anon-16Ff anon-16Ff http://flybase.org/reports/FBgn0026303 - gene - - - "HL-VII, anon-16Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004192 snRNA:U2:34ABb small nuclear RNA U2 at 34ABb http://flybase.org/reports/FBgn0004192 "FBgn0003919, FBgn0003921, FBgn0051854" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay "U2:34ABb, U2, dU2, U2 snRNA, U2-34ABb, U2-69E5, U2-131B, D.U2-2, 131B, U2 131B, Dm U2-131B, K6, snRNA:U2, snRNA-U2-131B, U2snRNA34ABb, CR31854, U2snRNA, snRNA:U2:34ABb, 34B U2" - CR31854 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067783 DPCoAC Dephosphocoenzyme A carrier http://flybase.org/reports/FBgn0067783 protein_coding_gene coenzyme A transmembrane transporter activity ; GO:0015228 | inferred from biological aspect of ancestor with PANTHER:PTN000641105 ADP transmembrane transporter activity ; GO:0015217 | inferred from biological aspect of ancestor with PANTHER:PTN000641105 AMP transmembrane transporter activity ; GO:0080122 | inferred from biological aspect of ancestor with PANTHER:PTN000641105 coenzyme A transmembrane transport ; GO:0035349 | inferred from biological aspect of ancestor with PANTHER:PTN000641105 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 ADP transport ; GO:0015866 | inferred from biological aspect of ancestor with PANTHER:PTN000641105 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000641105 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "att, CG4241, DPCoAC, dPCoAC, att-ORFA" "IPR002067:Mitochondrial carrier protein, IPR002167:Graves disease carrier protein, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG4241 11-Aug-17 DroID_v2017_08 "Drer\slc25a43, Drer\slc25a25b, Drer\slc25a23b, Drer\slc25a19, Drer\slc25a24, Drer\slc25a42, Drer\slc25a23a, Drer\slc25a25a, Drer\slc25a16" "Scer\YPR011C, Scer\LEU5, Scer\TPC1" "Cele\F17E5.2, Cele\slc-25A42, Cele\F55A11.4" "Xtro\slc25a24, Xtro\slc25a23, Xtro\slc25a25, Xtro\slc25a19, Xtro\slc25a42, Xtro\slc25a43" "Mmus\Slc25a43, Mmus\Slc25a19, Mmus\Slc25a42, Mmus\Slc25a25, Mmus\Slc25a23, Mmus\Slc25a24, Mmus\Slc25a16, Mmus\Slc25a41, Mmus\Slc25a54" "Hsap\SLC25A16, Hsap\SLC25A24, Hsap\SLC25A43, Hsap\SLC25A23, Hsap\SLC25A25, Hsap\SLC25A19, Hsap\SLC25A42, Hsap\SLC25A41" FBgn0265167 CR44236 - http://flybase.org/reports/FBgn0265167 non_protein_coding_gene - - - CR44236 - CR44236 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046632 anon-38E.4 anon-38E.4 http://flybase.org/reports/FBgn0046632 gene - - - "38E.4, anon-38E.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060480 l(3)S111001 lethal (3) S111001 http://flybase.org/reports/FBgn0060480 gene - - - "1110/01, l(3)S111001" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033486 dmpd dampened http://flybase.org/reports/FBgn0033486 protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from direct assay ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay inferred from mutant phenotype anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype" SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model nucleus ; GO:0005634 | inferred from direct assay "CG11866, FBXO13, dmpd" IPR001810:F-box domain CG11866 11-Aug-17 DroID_v2017_08 Drer\fbxo28 - Cele\ZC247.2 Xtro\fbxo28 Mmus\Fbxo28 Hsap\FBXO28 "viable,fertile" FBgn0035838 ldbr lariat debranching enzyme http://flybase.org/reports/FBgn0035838 protein_coding_gene RNA lariat debranching enzyme activity ; GO:0008419 | inferred from sequence or structural similarity with SGD:S000001632 inferred from sequence or structural similarity with protein_id:AAD53327 RNA lariat debranching enzyme activity ; GO:0008419 | inferred from sequence or structural similarity with UniProtKB:Q9UK59 RNA lariat debranching enzyme activity ; GO:0008419 | inferred from biological aspect of ancestor with PANTHER:PTN000304155 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000304155 RNA phosphodiester bond hydrolysis, endonucleolytic ; GO:0090502 | inferred from biological aspect of ancestor with PANTHER:PTN000304155 RNA splicing, via transesterification reactions ; GO:0000375 | inferred from sequence or structural similarity with UniProtKB:Q9UK59 RNA processing ; GO:0006396 | inferred from sequence or structural similarity with SGD:S000001632" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000304155 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9UK59 "ldbr, CG7942, Ldbr, Lbdr" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR007708:Lariat debranching enzyme, C-terminal, IPR029052:Metallo-dependent phosphatase-like" CG7942 11-Aug-17 DroID_v2017_08 Drer\dbr1 Scer\DBR1 Cele\dbr-1 Xtro\dbr1 Mmus\Dbr1 Hsap\DBR1 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0016830 l(1)MZ17 lethal (1) MZ17 http://flybase.org/reports/FBgn0016830 - gene - - - "l(1)MZ17, M17" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000164 bb bobbed http://flybase.org/reports/FBgn0000164 "FBgn0003454, FBgn0010322, FBgn0014124, FBgn0014125, FBgn0025282" rRNA_gene - - - "rDNA, flex, NO, rRNA, clone 1.69, ITS1, Xbb, snRNA-a, l(1)20Fa, anon-EST:Posey92, anon-EST:Liang-1.69, bb, 35S rRNA" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,viable,heat sensitive,female,wild-type,male,dominant,female fertile,poor" "macrochaeta,tergite,male genitalia,abdominal segment,ovary,germline clone,egg chamber,abdomen" FBgn0061117 l(3)S005310 lethal (3) S005310 http://flybase.org/reports/FBgn0061117 gene - - - "0053/10, l(3)S005310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage" FBgn0067628 CG33331 - http://flybase.org/reports/FBgn0067628 protein_coding_gene phosphatidate cytidylyltransferase activity ; GO:0004605 | inferred from sequence or structural similarity with UniProtKB:P53230 cardiolipin biosynthetic process ; GO:0032049 | inferred from sequence or structural similarity with UniProtKB:P53230 extrinsic component of mitochondrial inner membrane ; GO:0031314 | inferred from sequence or structural similarity with UniProtKB:P53230 "CG3641, BcDNA:SD17447, CG33331" IPR015222:Mitochondrial matrix Mmp37 CG33331 11-Aug-17 DroID_v2017_08 Drer\tamm41 Scer\TAM41 Cele\Y71F9B.2 Xtro\tamm41 Mmus\Tamm41 Hsap\TAMM41 DRSC29492 K 0.110647636 0.360996953 -0.141687394 -0.217891704 1.534495509 -0.146234172 FBgn0027381 Idefix\gag Idefix element gag http://flybase.org/reports/FBgn0027381 - transposable_element_gene - - - "ORF1, Idefix\gag, gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033459 CG12744 - http://flybase.org/reports/FBgn0033459 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 defense response to fungus ; GO:0050832 | inferred from mutant phenotype - CG12744 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG12744 11-Aug-17 DroID_v2017_08 Drer\prdm10 - Cele\ZK686.5 - "Mmus\Prdm10, Mmus\Zfp770" "Hsap\PRDM10, Hsap\ZNF770" "immune response defective,viable,fertile" "hemocyte,crystal cell" FBgn0264876 CR44067 - http://flybase.org/reports/FBgn0264876 non_protein_coding_gene - - - CR44067 - CR44067 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259106 dar8 dendritic arbor reduction 8 http://flybase.org/reports/FBgn0259106 gene - positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype - dar8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069933 CG41118 - http://flybase.org/reports/FBgn0069933 protein_coding_gene - - - CG41118 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263407 CR43453 - http://flybase.org/reports/FBgn0263407 non_protein_coding_gene - - - CR43453 - CR43453 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060504 l(3)S105407 lethal (3) S105407 http://flybase.org/reports/FBgn0060504 gene - - - "1054/07, l(3)S105407" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016649 Frda Frda http://flybase.org/reports/FBgn0016649 - gene - - - "Frd, Frda" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0002286 l(3)73Bb lethal (3) 73Bb http://flybase.org/reports/FBgn0002286 - gene - - - "l(3L)73Bb, l(3)std10, l(3)73Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0266098 rg rugose http://flybase.org/reports/FBgn0266098 protein_coding_gene protein kinase A binding ; GO:0051018 | inferred from direct assay neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype eye photoreceptor cell development ; GO:0042462 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG44835, AKAP, CG15465/CG6775, rg, Akap550, DAKAP550, fas, CG15466, CG6775, CG15464" "IPR011993:PH domain-like, IPR017986:WD40-repeat-containing domain, IPR000409:BEACH domain, IPR001680:WD40 repeat, IPR010508:Domain of unknown function DUF1088, IPR015943:WD40/YVTN repeat-like-containing domain, IPR023362:PH-BEACH domain, IPR016024:Armadillo-type fold, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR011989:Armadillo-like helical, IPR031570:Domain of unknown function DUF4704" CG44835 11-Aug-17 DroID_v2017_08 "Drer\lrba, Drer\nbeaa, Drer\nbeab, Drer\nbeal1" Scer\BPH1 "Cele\sorf-2, Cele\sel-2" "Xtro\nbea, Xtro\nbeal2, Xtro\nbeal1, Xtro\lrba" "Mmus\Lrba, Mmus\Nbeal2, Mmus\Nbeal1, Mmus\Nbea" "Hsap\NBEAL1, Hsap\LRBA, Hsap\NBEA, Hsap\NBEAL2" DRSC18049 EK -0.395888772 0.823397946 1.54694462 0.290017571 2.363878037 0.66322466 FBgn0016966 vm3 visible mutation-3 http://flybase.org/reports/FBgn0016966 - gene - - - vm3 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0060779 l(3)S060708 lethal (3) S060708 http://flybase.org/reports/FBgn0060779 gene - - - "0607/08, l(3)S060708" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0023041 l(2)46Eb lethal (2) 46Eb http://flybase.org/reports/FBgn0023041 "FBgn0019707, FBgn0019727" gene - - - "A, 28.19, 1.2, l(2)46CFu, l(2)46CFa, l(2)46Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002863 Acp95EF Accessory gland protein 95EF http://flybase.org/reports/FBgn0002863 FBgn0039171 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "mst316, mst 316, mst-3, mst316F, mst(3)ag-3, Mst95F, Mst95E, CG17924, Acp95EF, Acp, DTA-E, DTA-D" - CG17924 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC15857 I -2.090497657 0.906310634 0.063299046 -0.804405998 0.393053774 -0.30832586 FBgn0000697 fltC flight defective C http://flybase.org/reports/FBgn0000697 - gene - - - fltC - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,heat sensitive" FBgn0039602 CG1647 - http://flybase.org/reports/FBgn0039602 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000003381" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from electronic annotation with InterPro:IPR027755 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 CG1647 "IPR002068:Alpha crystallin/Hsp20 domain, IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027755:Transcription factor Ovo-like, IPR027775:C2H2- zinc finger protein family subset, IPR013087:Zinc finger C2H2-type" CG1647 11-Aug-17 DroID_v2017_08 "Drer\zgc:171929, Drer\ovol1, Drer\leo1, Drer\rp1, Drer\si:dkey-17e16.13, Drer\znf131" "Scer\RPN4, Scer\YFR016C" "Cele\Y5F2A.4, Cele\lin-48, Cele\lst-5, Cele\ztf-2" Xtro\leo1 "Mmus\Ibsp, Mmus\Ovol3, Mmus\Zfp770, Mmus\Rest, Mmus\Zfp655, Mmus\Dmp1, Mmus\Zfp131, Mmus\Rp1, Mmus\Ovol1, Mmus\Leo1, Mmus\Ovol2" "Hsap\OVOL2, Hsap\ZNF770, Hsap\RP1, Hsap\ZNF655, Hsap\DMP1, Hsap\IBSP, Hsap\REST, Hsap\ZNF131, Hsap\OVOL1, Hsap\OVOL3, Hsap\LEO1" "viable,fertile" FBgn0037757 CG8516 - http://flybase.org/reports/FBgn0037757 protein_coding_gene - - - "CG8516, FBgn0037757" - CG8516 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0050125 Ir56a Ionotropic receptor 56a http://flybase.org/reports/FBgn0050125 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir56a, DmelIR56a, CG30125, IR56a" - CG30125 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031329 CG14344 - http://flybase.org/reports/FBgn0031329 protein_coding_gene - - - CG14344 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001941 ifc infertile crescent http://flybase.org/reports/FBgn0001941 - protein_coding_gene sphingolipid delta-4 desaturase activity ; GO:0042284 | inferred from direct assay photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype ceramide biosynthetic process ; GO:0046513 | inferred from biological aspect of ancestor with PANTHER:PTN001767866 spermatogenesis ; GO:0007283 | traceable author statement spindle assembly involved in male meiosis ; GO:0007053 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011388 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity contractile ring ; GO:0070938 | inferred from direct assay Nebenkern ; GO:0016006 | inferred from direct assay "DES-1, des, des1, des-1, l(2)26Ab, l(2)gdh-2, ms(2)04875, CG9078, ifc, Ifc, Des1" "IPR005804:Fatty acid desaturase domain, IPR011388:Sphingolipid delta4-desaturase, IPR013866:Sphingolipid delta4-desaturase, N-terminal" CG9078 11-Aug-17 DroID_v2017_08 "Drer\degs2, Drer\degs1" - "Cele\F33D4.4, Cele\ttm-5" "Xtro\degs1, Xtro\degs3, Xtro\degs2" "Mmus\Degs1, Mmus\Degs2, Mmus\9130409I23Rik" "Hsap\DEGS2, Hsap\DEGS1" spermatogenesis && adult stage " spermatocyte

, testis

" adult stage | male " spermatid

, Nebenkern

, spermatocyte

" "male sterile,recessive,partially lethal - majority die,some die during embryonic stage,cytokinesis defective,male,lethal,lethal - all die before end of embryonic stage,some die during pupal stage" "testis,spermatocyte,spermatid,spermatid & nucleus,spindle,aster,meiotic cell cycle" FBgn0023024 l(3)82Ca lethal (3) 82Ca http://flybase.org/reports/FBgn0023024 - gene - - - l(3)82Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011193 l(1)302-1 lethal (1) 302-1 http://flybase.org/reports/FBgn0011193 FBgn0010202 gene - - - "302-1, l(1)302-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031711 CG6907 - http://flybase.org/reports/FBgn0031711 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000307203 RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000307203 phosphorylase kinase regulator activity ; GO:0008607 | inferred from sequence or structural similarity with UniProtKB:Q96EB1 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from biological aspect of ancestor with PANTHER:PTN000307203 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:Q96EB1 histone H4 acetylation ; GO:0043967 | inferred from biological aspect of ancestor with PANTHER:PTN000307203 histone H3 acetylation ; GO:0043966 | inferred from biological aspect of ancestor with PANTHER:PTN000307203 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000307203 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q96EB1 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000307203 Elongator holoenzyme complex ; GO:0033588 | inferred from biological aspect of ancestor with PANTHER:PTN000307203 transcription elongation factor complex ; GO:0008023 | inferred from biological aspect of ancestor with PANTHER:PTN000307203 transcription elongation factor complex ; GO:0008023 | inferred from sequence or structural similarity with UniProtKB:Q96EB1 histone acetyltransferase complex ; GO:0000123 | inferred from biological aspect of ancestor with PANTHER:PTN000307203 CG6907 IPR008728:Elongator complex protein 4 CG6907 11-Aug-17 DroID_v2017_08 Drer\elp4 Scer\ELP4 Cele\elpc-4 Xtro\elp4 Mmus\Elp4 Hsap\ELP4 "viable,fertile" DRSC02999 IE 0.636640764 -5.667336989 -1.369778518 -3.819421583 -1.255729381 0.938592083 FBgn0063395 Stalker2\ORF4 Stalker2 element ORF4 http://flybase.org/reports/FBgn0063395 transposable_element_gene - - - "rom\ORF4, Stalker2\ORF4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265451 CR44351 - http://flybase.org/reports/FBgn0265451 non_protein_coding_gene - - - CR44351 - CR44351 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266677 CR45167 - http://flybase.org/reports/FBgn0266677 non_protein_coding_gene - - - CR45167 - CR45167 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058091 CG40091 - http://flybase.org/reports/FBgn0058091 protein_coding_gene - - - CG40091 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026209 limo limo http://flybase.org/reports/FBgn0026209 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available limo - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002725 macrofine macrofine http://flybase.org/reports/FBgn0002725 - gene - - - "macrofine, mf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,female,reduced,male fertile" macrochaeta FBgn0013669 ms(3)neo5 ms(3)neo5 http://flybase.org/reports/FBgn0013669 - gene - - - ms(3)neo5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,male semi-sterile,recessive" FBgn0001491 l(1)10Bb lethal (1) 10Bb http://flybase.org/reports/FBgn0001491 FBgn0027286 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000454176 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG1639, l(1)10Bb, l(1)G0169, 10Ba, l(1)GLM14, l(1)G14, L(1)10Bb" "IPR018230:BUD31/G10-related, conserved site, IPR001748:G10 protein" CG1639 11-Aug-17 DroID_v2017_08 Drer\bud31 Scer\BUD31 Cele\C07A9.2 Xtro\bud31 Mmus\Bud31 Hsap\BUD31 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0086447 l(2)37Cg lethal (2) 37Cg http://flybase.org/reports/FBgn0086447 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR008193 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR009025 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000358824 DNA-directed RNA polymerase activity ; GO:0003899 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q09177 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000358824 transcription from RNA polymerase I promoter ; GO:0006360 | inferred from sequence or structural similarity with UniProtKB:Q09177 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from sequence or structural similarity with UniProtKB:Q09177 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from sequence or structural similarity with UniProtKB:Q09177 microtubule associated complex ; GO:0005875 | inferred from direct assay DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000358824 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN000358824 "l(2)37Cg, CG10685, Cg" "IPR009025:DNA-directed RNA polymerase, RBP11-like dimerisation domain, IPR008193:DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site, IPR033898:DNA-directed RNA polymerases I and III subunit AC19" CG10685 11-Aug-17 DroID_v2017_08 Drer\polr1d Scer\RPC19 Cele\rpac-19 Xtro\polr1d.2 Mmus\Polr1d Hsap\POLR1D FBgn0027118 mei-P14 mei-P14 http://flybase.org/reports/FBgn0027118 - gene - - - mei-P14 - - 11-Aug-17 DroID_v2017_08 - - - - - - meiotic cell cycle defective FBgn0267949 CR46229 - http://flybase.org/reports/FBgn0267949 non_protein_coding_gene - - - "CR46229, lincRNA.280" - CR46229 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000038 nAChRbeta1 nicotinic Acetylcholine Receptor beta1 http://flybase.org/reports/FBgn0000038 - protein_coding_gene acetylcholine-gated cation channel activity ; GO:0022848 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006029, InterPro:IPR006201 synaptic transmission, cholinergic ; GO:0007271 | inferred from expression pattern" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006201 acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity postsynaptic membrane ; GO:0045211 | inferred from direct assay" "beta1 nAChR, nAChR, ARD, CG12606, ard, AChR, beta 64B, Acr64B, Ard, AChR64B, CG11348, AcrD, AchR64B, nAcRbeta-64B, Dbeta1, CG11348-PA, nAChRbeta1, nAcR64B, nAChR-beta64B" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG11348 11-Aug-17 DroID_v2017_08 "Drer\chrnb2b, Drer\tsen54, Drer\chrnb1l, Drer\si:ch73-380n15.2, Drer\chrna3, Drer\si:ch211-39a7.1, Drer\chrnb3b, Drer\chrng, Drer\chrna10a, Drer\htr3b, Drer\chrne, Drer\chrna9, Drer\chrna2a, Drer\chrnb2l, Drer\LOC100334841, Drer\LOC101884593, Drer\chrna2b, Drer\chrnd, Drer\chrnb3a, Drer\si:ch211-256e16.4, Drer\chrnb4, Drer\chrna6, Drer\LOC798522, Drer\chrna5, Drer\htr3a, Drer\LOC101882451, Drer\chrna4b, Drer\chrnb1, Drer\chrna1" - "Cele\acr-9, Cele\lgc-24, Cele\lgc-28, Cele\lev-8, Cele\lgc-21, Cele\lgc-30, Cele\acr-24, Cele\acr-10, Cele\acr-2, Cele\acr-16, Cele\eat-2, Cele\unc-38, Cele\acr-23, Cele\acr-6, Cele\des-2, Cele\unc-63, Cele\acr-8, Cele\lgc-10, Cele\acr-21, Cele\acr-14, Cele\lgc-27, Cele\acr-25, Cele\lgc-31, Cele\acr-7, Cele\acr-20, Cele\lgc-26, Cele\lgc-22, Cele\acr-11, Cele\pbo-5, Cele\acr-18, Cele\unc-29, Cele\lgc-4, Cele\deg-3, Cele\acr-19, Cele\acr-3, Cele\acr-17, Cele\lgc-20, Cele\acr-5, Cele\lev-1, Cele\lgc-25, Cele\pbo-6, Cele\acr-12, Cele\acr-15, Cele\lgc-23, Cele\lgc-9" "Xtro\chrnd, Xtro\chrnb3, Xtro\chrne, Xtro\chrna6, Xtro\chrnb2, Xtro\chrna4, Xtro\chrna9, Xtro\chrna1.2, Xtro\chrna2, Xtro\chrng, Xtro\chrna7, Xtro\chrna5, Xtro\chrna1" "Mmus\Chrnb2, Mmus\Chrnb4, Mmus\Chrna7, Mmus\Chrnd, Mmus\Chrna4, Mmus\Chrnb1, Mmus\Chrna3, Mmus\Chrne, Mmus\Chrna10, Mmus\Chrna5, Mmus\Chrna9, Mmus\Chrng, Mmus\Htr3b, Mmus\Htr3a, Mmus\Chrnb3, Mmus\Chrna6, Mmus\Chrna1, Mmus\Chrna2" "Hsap\CHRNB4, Hsap\CHRNA10, Hsap\CHRND, Hsap\HTR3B, Hsap\HTR3C, Hsap\CHRFAM7A, Hsap\CHRNA6, Hsap\HTR3A, Hsap\HTR3D, Hsap\ZACN, Hsap\CHRNA5, Hsap\HTR3E, Hsap\CHRNB1, Hsap\CHRNB2, Hsap\CHRNA2, Hsap\CHRNA3, Hsap\CHRNA1, Hsap\CHRNA9, Hsap\CHRNG, Hsap\CHRNB3, Hsap\CHRNE, Hsap\CHRNA7, Hsap\CHRNA4" " larval stage | second instar , embryonic stage -- adult stage , embryonic stage | stage 13-17 , adult stage , pupal stage && adult stage , embryonic stage | mid-late , pupal stage&&adult stage " " ventral nerve cord

, central nervous system

, cell

, supraesophageal ganglion

, medulla cortex

, lamina

, lamina cortex

, lobula plate cortex

, larval brain

, subesophageal ganglion

, embryonic central nervous system | presumptive

, medulla

" "viable,partially lethal - majority die,some die during pupal stage" FBgn0067747 l(1)G0243 lethal (1) G0243 http://flybase.org/reports/FBgn0067747 gene - - - l(1)G0243 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040963 CG18662 - http://flybase.org/reports/FBgn0040963 protein_coding_gene phosphohistidine phosphatase activity ; GO:0008969 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:30033 peptidyl-histidine dephosphorylation ; GO:0035971 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:30033 CG18662 IPR007702:Janus CG18662 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-51e6.1, Drer\phpt1" - Cele\phip-1 Xtro\phpt1 Mmus\Phpt1 Hsap\PHPT1 viable FBgn0060608 l(3)S090411b lethal (3) S090411b http://flybase.org/reports/FBgn0060608 gene - - - "0904/11, l(3)S090411b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086054 snoRNA:Me18S-G1358b - http://flybase.org/reports/FBgn0086054 snoRNA_gene - - - "snoRNA:Me18S-G1358b, Me18S-Gm1358b, CR34683" - CR34683 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263029 CG43324 - http://flybase.org/reports/FBgn0263029 protein_coding_gene "signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR001770, InterPro:IPR015898 molecular_function ; GO:0003674 | no biological data available" "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR001770, InterPro:IPR015898 biological_process ; GO:0008150 | no biological data available" "heterotrimeric G-protein complex ; GO:0005834 | inferred from electronic annotation with InterPro:IPR001770, InterPro:IPR015898 cellular_component ; GO:0005575 | no biological data available" "CG15844, CG43324" "IPR001770:G-protein, gamma subunit, IPR015898:G-protein gamma-like domain" CG43324 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-204f11.64, Drer\gngt1, Drer\gng3, Drer\gngt2b, Drer\gng8, Drer\gng10, Drer\si:dkey-44g17.6, Drer\gng2, Drer\gngt2a, Drer\gng12a, Drer\si:dkey-117i10.1, Drer\gng5, Drer\gng7, Drer\gng13b, Drer\gng13a" - Cele\gpc-2 "Xtro\gngt1, Xtro\gngt2, Xtro\gng13, Xtro\gng5, Xtro\gng2, Xtro\gng7" "Mmus\Gng3, Mmus\Gng10, Mmus\Gm5741, Mmus\Gng5, Mmus\Gng2, Mmus\Gng12, Mmus\Gngt2, Mmus\Gng4, Mmus\Gngt1, Mmus\Gng7, Mmus\Gng11, Mmus\Gng8, Mmus\Gng13" "Hsap\GNG7, Hsap\GNG3, Hsap\GNG11, Hsap\GNGT2, Hsap\GNG8, Hsap\GNGT1, Hsap\GNG10, Hsap\GNG2, Hsap\GNG13, Hsap\GNG4, Hsap\GNG5, Hsap\GNG12" "lethal,recessive" FBgn0025136 su(RpII140[Z36])S11 su(RpII140[Z36])S11 http://flybase.org/reports/FBgn0025136 - gene - - - "Z36[S11], su(RpII140[Z36])S11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032016 Mettl14 Methyltransferase like 14 http://flybase.org/reports/FBgn0032016 protein_coding_gene mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity ; GO:0016422 | inferred from sequence or structural similarity with UniProtKB:Q86U44 "RNA methylation ; GO:0001510 | inferred from sequence or structural similarity with UniProtKB:Q86U44 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q86U44 "dMettl14, Mettl14, CG7818" "IPR007757:MT-A70-like, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG7818 11-Aug-17 DroID_v2017_08 Drer\mettl14 Scer\KAR4 - Xtro\mettl14 Mmus\Mettl14 Hsap\METTL14 "viable,fertile,visible" mesothoracic tergum FBgn0028840 BG:DS09219.1 BG:DS09219.1 http://flybase.org/reports/FBgn0028840 gene - - - "DS09219.1, BG:DS09219.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024645 l(2)k09931 lethal (2) k09931 http://flybase.org/reports/FBgn0024645 - gene - - - "99/31, l(2)k09931" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal" "imaginal disc,wing,wing vein" FBgn0023517 Pgam5 Phosphoglycerate mutase 5 http://flybase.org/reports/FBgn0023517 - protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from direct assay protein serine/threonine kinase activator activity ; GO:0043539 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Pink1 phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay kinase binding ; GO:0019900 | inferred from physical interaction with UniProtKB:Q24458 phosphoglycerate mutase activity ; GO:0004619 | NOT inferred from direct assay positive regulation of mitochondrial fission ; GO:0090141 | inferred from direct assay response to heat ; GO:0009408 | inferred from mutant phenotype response to anesthetic ; GO:0072347 | inferred from mutant phenotype regulation of mitochondrion organization ; GO:0010821 | inferred from mutant phenotype inferred from genetic interaction with Pink1 protein dephosphorylation ; GO:0006470 | inferred from direct assay peptidyl-threonine dephosphorylation ; GO:0035970 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q96HS1 integral component of membrane ; GO:0016021 | inferred from sequence model "EG:63B12.4, Pgam5, dPGAM5, PGAM5, CG14816, DPGAM5" "IPR013078:Histidine phosphatase superfamily, clade-1, IPR029033:Histidine phosphatase superfamily" CG14816 11-Aug-17 DroID_v2017_08 Drer\pgam5 - Cele\pgam-5 Xtro\pgam5 Mmus\Pgam5 Hsap\PGAM5 "heat stress response defective,viable,fertile,long lived,locomotor behavior defective,decreased cell number,short lived,chemical sensitive,recessive" "mitochondrion,adult mushroom body,Kenyon cell,mitochondrionda.G32,embryonic/larval hemocyte | third instar larval stage" FBgn0260953 CG42585 - http://flybase.org/reports/FBgn0260953 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42585 "IPR008598:Drought induced 19 protein type, zinc-binding domain, IPR000433:Zinc finger, ZZ-type" CG42585 11-Aug-17 DroID_v2017_08 Drer\kcmf1 - Cele\ZK652.6 Xtro\kcmf1 Mmus\Kcmf1 Hsap\KCMF1 FBgn0040557 CG14364 - http://flybase.org/reports/FBgn0040557 protein_coding_gene - - - CG14364 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015552 teg tegamino http://flybase.org/reports/FBgn0015552 - gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - teg - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "egg chamber,nurse cell" FBgn0026375 RhoGAPp190 Rho GTPase activating protein p190 http://flybase.org/reports/FBgn0026375 "FBgn0030856, FBgn0030857, FBgn0046792, FBgn0052555, FBgn0062491" protein_coding_gene GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806 semaphorin receptor binding ; GO:0030215 | inferred from physical interaction with Sema1a GTPase activator activity ; GO:0005096 | inferred from genetic interaction with Rho1 Rho protein signal transduction ; GO:0007266 | inferred from genetic interaction with Rho1 negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype defasciculation of motor neuron axon ; GO:0007415 | inferred from mutant phenotype regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with LIMK1 cellular_component ; GO:0005575 | no biological data available "CG8267, 8267, p190 RhoGAP, p190RhoGAP, CG8240, RhoGAP-16B12, D-p190, DRhoGAP, RhoGAP, CG32555, BcDNA:GM05133, BcDNA:GH17919, RhoGAPp190, RhoGAP P190, p190-RhoGAP, p190, mdcds_56566" "IPR000198:Rho GTPase-activating protein domain, IPR008936:Rho GTPase activation protein, IPR001806:Small GTPase superfamily, IPR032835:Rho GTPase-activating protein, FF domain, IPR002713:FF domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG32555 11-Aug-17 DroID_v2017_08 "Drer\arhgap23b, Drer\arhgap35, Drer\arhgap23a, Drer\arhgap21b, Drer\arhgap35, Drer\arhgap5" "Scer\RGA2, Scer\RGA1" "Cele\rga-5, Cele\pac-1" "Xtro\arhgap35, Xtro\arhgap5" "Mmus\Arhgap21, Mmus\Arhgap35, Mmus\Arhgap5, Mmus\Arhgap23" "Hsap\ARHGAP5, Hsap\ARHGAP21, Hsap\ARHGAP23, Hsap\ARHGAP35" "neuroanatomy defective,viable,fertile,lethal,body color defective" "intersegmental nerve branch ISNb of A1-7,medial lobe & axoney-OK107,mushroom body beta-lobe,vertical lobe of adult mushroom body,adult mushroom body,wing hair,supernumerary,mesothoracic tergum" FBgn0261925 CG42792 - http://flybase.org/reports/FBgn0261925 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42792, HDC02744" - CG42792 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031074 SkpE SKP1-related E http://flybase.org/reports/FBgn0031074 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000002736 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with SGD:S000002736 neurogenesis ; GO:0022008 | inferred from mutant phenotype SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with SGD:S000002736 "CG11942, Skp, SkpE, skpE" "IPR011333:SKP1/BTB/POZ domain, IPR001232:S-phase kinase-associated protein 1-like, IPR016072:SKP1 component, dimerisation, IPR016073:SKP1 component, POZ domain, IPR016897:S-phase kinase-associated protein 1" CG11942 11-Aug-17 DroID_v2017_08 Drer\skp1 "Scer\ELC1, Scer\SKP1" "Cele\skr-17, Cele\skr-18, Cele\skr-9, Cele\skr-20, Cele\skr-16, Cele\skr-5, Cele\skr-21, Cele\skr-6, Cele\skr-15, Cele\skr-13, Cele\skr-10, Cele\skr-12, Cele\skr-1, Cele\skr-19, Cele\skr-8, Cele\skr-3, Cele\skr-2, Cele\skr-7, Cele\skr-14, Cele\skr-4" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 "viable,visible,body color defective,lethal,neuroanatomy defective" "chaeta,supernumerary,mesothoracic tergum,ganglion mother cell" FBgn0028005 l(3)S116415 lethal (3) S116415 http://flybase.org/reports/FBgn0028005 gene - - - "1164/15, l(3)S116415" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011336 Stt3B Catalytic subunit 3B of the oligosaccharyltransferase complex http://flybase.org/reports/FBgn0011336 FBgn0027069 protein_coding_gene oligosaccharyl transferase activity ; GO:0004576 | inferred from sequence or structural similarity dolichyl-diphosphooligosaccharide-protein glycotransferase activity ; GO:0004579 | inferred from biological aspect of ancestor with PANTHER:PTN000356206 post-translational protein modification ; GO:0043687 | inferred from biological aspect of ancestor with PANTHER:PTN000356206 protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from biological aspect of ancestor with PANTHER:PTN000356206 oligosaccharyltransferase complex ; GO:0008250 | inferred from sequence or structural similarity oligosaccharyltransferase complex ; GO:0008250 | inferred from biological aspect of ancestor with PANTHER:PTN000356206 endomembrane system ; GO:0012505 | inferred from direct assay "l(3)j2D9, CG7748, BcDNA.GM01838, anon-WO03054008.7, BcDNA:GM01838, Stt3B, STT, OstStt3" "IPR003674:Oligosaccharyl transferase, STT3 subunit" CG7748 11-Aug-17 DroID_v2017_08 "Drer\stt3a, Drer\stt3b" Scer\STT3 Cele\stt-3 "Xtro\stt3a, Xtro\stt3b" "Mmus\Stt3a, Mmus\Stt3b" "Hsap\STT3B, Hsap\STT3A" "lethal,recessive" FBgn0002550 lgt leg tumor http://flybase.org/reports/FBgn0002550 - gene - - - lgt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,sterile,viable,poor,melanotic mass phenotype" melanotic mass FBgn0263603 Zn72D Zinc-finger protein at 72D http://flybase.org/reports/FBgn0263603 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003604 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 phagocytosis ; GO:0006909 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "zn72D, ZN72D, Zn72D, l(3)72Dk, CG5215" "IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR006561:DZF domain, IPR013087:Zinc finger C2H2-type" CG5215 11-Aug-17 DroID_v2017_08 "Drer\zfr2, Drer\strbp, Drer\ilf3b, Drer\ilf3a, Drer\zfr" Scer\TAD1 Cele\Y95B8A.8 "Xtro\strbp, Xtro\ilf3, Xtro\zfr" "Mmus\Ilf3, Mmus\Zfr2, Mmus\Zfr, Mmus\Strbp" "Hsap\ZFR, Hsap\ZFR2, Hsap\ILF3, Hsap\STRBP" FBgn0028746 CG18508 - http://flybase.org/reports/FBgn0028746 protein_coding_gene signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000335828 - - "EG:140G11.3, CG4015, CG18508" IPR026776:Uncharacterised protein family UPF0729 CG18508 11-Aug-17 DroID_v2017_08 - - Cele\F18A11.3 Xtro\c18orf32 Mmus\BC031181 Hsap\C18orf32 FBgn0028969 deltaCOP Coat Protein (coatomer) delta http://flybase.org/reports/FBgn0028969 protein_coding_gene - "retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from electronic annotation with InterPro:IPR027059 phagocytosis ; GO:0006909 | inferred from mutant phenotype larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from direct assay protein secretion ; GO:0009306 | inferred from mutant phenotype" COPI vesicle coat ; GO:0030126 | inferred from electronic annotation with InterPro:IPR027059 "deltaCOP, ARCN1, DM63B12S, DeltaCop, CG14813, delta-Cop, EG:63B12.10, l(1)G0051, 63B12S, l(1)G0301, l(1)G0450, Arch, ESTS:63B12S, anon-WO03040301.246, deltaCop, Delta COP" "IPR011012:Longin-like domain, IPR027059:Coatomer delta subunit, IPR028565:Mu homology domain, IPR022775:AP complex, mu/sigma subunit" CG14813 11-Aug-17 DroID_v2017_08 "Drer\arcn1a, Drer\arcn1b" Scer\RET2 Cele\copd-1 Xtro\arcn1 Mmus\Arcn1 Hsap\ARCN1 embryonic stage -- adult stage "visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,male,female" "wing,embryonic/larval dorsal trunk,embryonic/larval salivary gland" DRSC25961 IEK 0.180539541 1.688872606 1.303964135 -2.911616603 -0.314261504 -1.567055115 FBgn0036639 CG4229 - http://flybase.org/reports/FBgn0036639 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4229 IPR004011:GYR motif CG4229 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002987 Off Off http://flybase.org/reports/FBgn0002987 - gene - - - Off - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "macrochaeta,eye" FBgn0034278 CG14488 - http://flybase.org/reports/FBgn0034278 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14488 - CG14488 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC06460 I -2.160215434 0.258909593 0.203609301 0.588963354 1.351300754 0.334573812 FBgn0023035 l(2)46Eh lethal (2) 46Eh http://flybase.org/reports/FBgn0023035 FBgn0019706 gene - - - "R, 29.26, l(2)46CFv, l(2)46Eh" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000123 Ars-region1 Autonomous replicating sequence region 1 http://flybase.org/reports/FBgn0000123 - region - - - "PHa640, Ars-region1, Ars1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033602 Cpr47Ee Cuticular protein 47Ee http://flybase.org/reports/FBgn0033602 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG13222, Cpr47Ee, DmelCpr47Ee" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG13222 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - DRSC23164 K -0.400088614 -1.783018957 FBgn0051227 CG31227 - http://flybase.org/reports/FBgn0051227 protein_coding_gene - - - CG31227 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083287 E(smoDN)2101 Enhancer of smoDN 2101 http://flybase.org/reports/FBgn0083287 gene - - - E(smoDN)2101 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035001 Slik Sterile20-like kinase http://flybase.org/reports/FBgn0035001 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype" protein phosphorylation ; GO:0006468 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype positive regulation of peptidyl-threonine phosphorylation ; GO:0010800 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype metaphase/anaphase transition of mitotic cell cycle ; GO:0007091 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype regulation of localization ; GO:0032879 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype cleavage furrow ; GO:0032154 | inferred from direct assay mitotic spindle midzone ; GO:1990023 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "Plkk1, CG4527, DPlkk1, slk, SLK, dPlkk/Slik, Plkk/Slik, Slk, SLIK, Slik, PLKK1, Slik1, dPlkk, slik" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR022165:Polo kinase kinase" CG4527 11-Aug-17 DroID_v2017_08 "Drer\slkb, Drer\rock2b, Drer\slka, Drer\stk10, Drer\si:dkey-81j8.6" "Scer\GIN4, Scer\KCC4, Scer\KIC1, Scer\USO1, Scer\BCK1" Cele\gck-4 "Xtro\stk10, Xtro\slk" "Mmus\Stk10, Mmus\Slk" "Hsap\SLK, Hsap\STK10" "increased cell death,somatic clone,partially lethal - majority die,small body,developmental rate defective,recessive,lethal - all die before end of larval stage,partially,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,mitotic cell cycle defective,cell non-autonomous,viable" "wing,somatic clone,wing & epithelial cell,wing & epithelial cell | ectopic,rhabdomere,ommatidium & microvillus | somatic clone,1st posterior cell,peripodial epithelium" FBgn0037078 CG12971 - http://flybase.org/reports/FBgn0037078 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12971 - CG12971 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0005443 l(1)v146 lethal (1) v146 http://flybase.org/reports/FBgn0005443 - gene - - - "l(1)146, l(1)v146" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016663 Hrp39 Hrp39 http://flybase.org/reports/FBgn0016663 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "hrp39, Hrp39" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082967 snoRNA:Psi28S-3327a snoRNA:Psi28S-3327a http://flybase.org/reports/FBgn0082967 snoRNA_gene - - - "snoRNA:Psi28S-3327a, Psi28S-3327a, psi28S-3327a, Psi 28S-3327a, CR34642, pug28S-3327, chr3L:13016676..13016828" - CR34642 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000485 dow downy http://flybase.org/reports/FBgn0000485 - gene - - - dow - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,male sterile" "Nebenkern,spermatid,spermatocyte & nucleus,macrochaeta" FBgn0266639 CR45146 - http://flybase.org/reports/FBgn0266639 non_protein_coding_gene - - - CR45146 - CR45146 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023454 Cad47B Cad47B http://flybase.org/reports/FBgn0023454 - gene - - - "cad47B, Cad49, Cad47B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028002 l(3)S119608 lethal (3) S119608 http://flybase.org/reports/FBgn0028002 gene - - - "1196/08, l(3)S119608" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0064244 ELK1 ELK1 http://flybase.org/reports/FBgn0064244 gene - - - "ELK1, ELK-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069930 CG41121 - http://flybase.org/reports/FBgn0069930 protein_coding_gene - - - CG41121 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031365 CG17650 - http://flybase.org/reports/FBgn0031365 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG17650 - CG17650 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC00510 E 0.959538892 -0.062342568 1.74378216 5.190413662 -0.565726668 -0.108142915 FBgn0085671 CG41529 - http://flybase.org/reports/FBgn0085671 protein_coding_gene - - - CG41529 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039200 CG13616 - http://flybase.org/reports/FBgn0039200 protein_coding_gene - - - CG13616 IPR006631:Protein of unknown function DM4/12 CG13616 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065749 l(2)SH0499 lethal (2) SH0499 http://flybase.org/reports/FBgn0065749 gene - - - "l(2)SH0499, l(2)SH2 0499" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262581 CG43121 - http://flybase.org/reports/FBgn0262581 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43121 - CG43121 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004185 snRNA:U1:95Ca small nuclear RNA U1 at 95Ca http://flybase.org/reports/FBgn0004185 "FBgn0003915, FBgn0003918, FBgn0026851, FBgn0051341" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity "snRNA:U1, U1, U1 snRNA, U1-95.1, DMU1951, U1a-95Ca, U1a, U1951, U1snRNA, u1a, U1snRNA 95.1, K5, snRNA-U1-95.1, U1snRNA95Ca, CR31341, snRNA:U1:95Ca, U1:95Ca, U1-95Ca, U1:95C, 95C U1" - CR31341 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003423 slgA sluggish A http://flybase.org/reports/FBgn0003423 - protein_coding_gene proline dehydrogenase activity ; GO:0004657 | inferred from sequence or structural similarity with UniProtKB:O43272 proline dehydrogenase activity ; GO:0004657 | inferred from mutant phenotype FAD binding ; GO:0071949 | inferred from sequence or structural similarity with UniProtKB:O43272 FAD binding ; GO:0071949 | inferred from biological aspect of ancestor with PANTHER:PTN000357758 proline catabolic process ; GO:0006562 | inferred from sequence or structural similarity with UniProtKB:O43272 locomotory behavior ; GO:0007626 | inferred from mutant phenotype glutamate biosynthetic process ; GO:0006537 | inferred from sequence or structural similarity with UniProtKB:O43272 proline catabolic process to glutamate ; GO:0010133 | inferred from biological aspect of ancestor with PANTHER:PTN000357758 proline catabolic process ; GO:0006562 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:O43272 mitochondrion ; GO:0005739 | inferred from direct assay "PRODH, slg, tu3, sl, EE85, CG1417, slgA" "IPR002872:Proline dehydrogenase domain, IPR015659:Proline oxidase family, IPR029041:FAD-linked oxidoreductase-like" CG1417 11-Aug-17 DroID_v2017_08 "Drer\prodha, Drer\zgc:92040, Drer\prodhb" Scer\PUT1 Cele\B0513.5 "Xtro\prodh2, Xtro\prodh" "Mmus\Prodh, Mmus\Prodh2" "Hsap\PRODH2, Hsap\LOC102724788, Hsap\PRODH" embryonic stage " anal pad

, embryonic central nervous system

" "uncoordinated,hypoactive,recessive,locomotor behavior defective,behavior defective,wild-type,viable" FBgn0017431 anon-4Bc anon-4Bc http://flybase.org/reports/FBgn0017431 - gene - - - anon-4Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267634 CR45972 - http://flybase.org/reports/FBgn0267634 non_protein_coding_gene - - - "CR45972, Dm_3L:111571" - CR45972 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036340 SRm160 SRm160 http://flybase.org/reports/FBgn0036340 protein_coding_gene - "mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR002483 genitalia development ; GO:0048806 | inferred from mutant phenotype somatic sex determination ; GO:0018993 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 positive regulation of programmed cell death ; GO:0043068 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay exon-exon junction complex ; GO:0035145 | traceable author statement catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG11274, SRm160, SRM160" IPR002483:PWI domain CG11274 11-Aug-17 DroID_v2017_08 Drer\srrm1 - Cele\rsr-1 - Mmus\Srrm1 Hsap\SRRM1

"viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0033953 CG12861 - http://flybase.org/reports/FBgn0033953 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12861 "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG12861 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025175 l(2)38Da lethal (2) 38Da http://flybase.org/reports/FBgn0025175 - gene - - - l(2)38Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264618 CR43958 - http://flybase.org/reports/FBgn0264618 non_protein_coding_gene - - - CR43958 - CR43958 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266585 tRNA:Leu-CAG-1-8 transfer RNA:Leucine-CAG 1-8 http://flybase.org/reports/FBgn0266585 tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "AE002647.trna1-LeuCAG, tRNA:L:CAG:AE002647, CR32456, tRNA[Leu][[2]], tRNA:leu2:79F, tRNA:L2:79F, tRNA[Leu], tRNA[LEU], chr3L.trna32-LeuCAG, tRNA-Leu-CAG-1-8, tRNA:Leu-CAG-1-8, tRNA:CR32456, CUG" - CR32456 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035444 CG12012 - http://flybase.org/reports/FBgn0035444 protein_coding_gene - - - CG12012 IPR019317:Brain protein I3 CG12012 11-Aug-17 DroID_v2017_08 Drer\bri3 - - Xtro\bri3 Mmus\Bri3 Hsap\BRI3 viable FBgn0013546 l(2)M11 lethal (2) M11 http://flybase.org/reports/FBgn0013546 - gene - - - l(2)M11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259953 Sfp24Bd Seminal fluid protein 24Bd http://flybase.org/reports/FBgn0259953 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG42463, Sfp24Bd" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42463 11-Aug-17 DroID_v2017_08 "Drer\tfpi2, Drer\ambp" - - - "Mmus\Tfpi, Mmus\Spint4, Mmus\Ambp" "Hsap\AMBP, Hsap\TFPI, Hsap\SPINT4" FBgn0022325 l(1)A36.3 lethal (1) A36.3 http://flybase.org/reports/FBgn0022325 - gene - - - "A36.3, l(1)A36.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044423 M80-A33 M80-A33 http://flybase.org/reports/FBgn0044423 gene molecular_function ; GO:0003674 | no biological data available eye photoreceptor cell differentiation ; GO:0001754 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "M80#A33, M80-A33" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye photoreceptor cell,somatic clone" FBgn0265864 CR44653 - http://flybase.org/reports/FBgn0265864 non_protein_coding_gene - - - CR44653 - CR44653 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033998 row relative of woc http://flybase.org/reports/FBgn0033998 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 chromatin binding ; GO:0003682 | contributes_to inferred from physical interaction with woc protein binding ; GO:0005515 | inferred from physical interaction with woc inferred from physical interaction with HP1c protein binding ; GO:0005515 | inferred from physical interaction with HP1c "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay euchromatin ; GO:0000791 | colocalizes_with inferred from direct assay protein complex ; GO:0043234 | inferred from direct assay "anon-WO0118547.194, CG8092, row, Row" IPR013087:Zinc finger C2H2-type CG8092 11-Aug-17 DroID_v2017_08 "Drer\znf280d, Drer\pogzb, Drer\pogza" Scer\PDC2 Cele\row-1 Xtro\znf280d "Mmus\Zfp280b, Mmus\Zfp280d, Mmus\Zfp280c, Mmus\Pogz" "Hsap\ZNF280B, Hsap\POGZ, Hsap\ZNF280A, Hsap\ZNF280D, Hsap\ZNF280C" "lethal - all die before end of pupal stage,some die during pupal stage,viable,planar polarity defective,fertile,lethal" FBgn0034482 CG18416 - http://flybase.org/reports/FBgn0034482 protein_coding_gene - - - CG18416 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043037 l(2)42Bg lethal (2) 42Bg http://flybase.org/reports/FBgn0043037 gene - - - l(2)42Bg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001736 l(1)HM4 lethal (1) HM4 http://flybase.org/reports/FBgn0001736 - gene - - - l(1)HM4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0050467 CG30467 - http://flybase.org/reports/FBgn0050467 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN001159395 "CG8185, CG30467" IPR011989:Armadillo-like helical CG30467 11-Aug-17 DroID_v2017_08 Drer\saal1 - - Xtro\saal1 Mmus\Saal1 Hsap\SAAL1 viable FBgn0010765 l(3)01969 lethal (3) 01969 http://flybase.org/reports/FBgn0010765 - gene - - - l(3)01969 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025516 fs(3)82CDb fs(3)82CDb http://flybase.org/reports/FBgn0025516 - gene - - - fs(3)82CDb - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0000426 SmF Small ribonucleoprotein particle protein SmF http://flybase.org/reports/FBgn0000426 FBgn0063188 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:11162 "spliceosomal snRNP assembly ; GO:0000387 | inferred from electronic annotation with InterPro:IPR034100 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000006386 mRNA splicing, via spliceosome ; GO:0000398 | non-traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" small nucleolar ribonucleoprotein complex ; GO:0005732 | inferred from electronic annotation with InterPro:IPR016487 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000006386 precatalytic spliceosome ; GO:0071011 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000006386 small nuclear ribonucleoprotein complex ; GO:0030532 | non-traceable author statement catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG16792, deb-b, Deb-B, Deb, BcDNA:GM23968, snRNP-F, SmF, DebB, dF, F-Sm" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR016487:Sm-like protein Lsm6/SmF, IPR034100:Small nuclear ribonucleoprotein F" CG16792 11-Aug-17 DroID_v2017_08 "Drer\lsm6, Drer\snrpf" Scer\SMX3 "Cele\snr-5, Cele\lsm-6" "Xtro\lsm6, Xtro\snrpf" "Mmus\LOC102638183, Mmus\Lsm6, Mmus\Snrpf" "Hsap\LSM6, Hsap\SNRPF" FBgn0044020 Roc2 Regulator of cullins 2 http://flybase.org/reports/FBgn0044020 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR024766 zinc ion binding ; GO:0008270 | inferred from sequence model cullin family protein binding ; GO:0097602 | inferred from physical interaction with Cul5 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay" protein ubiquitination ; GO:0016567 | inferred from direct assay Cul5-RING ubiquitin ligase complex ; GO:0031466 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG8998, dRoc2, BcDNA:RE61847, Roc2, Roc, roc2" "IPR001841:Zinc finger, RING-type, IPR024766:Zinc finger, RING-H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8998 11-Aug-17 DroID_v2017_08 "Drer\rnf7, Drer\rbx1" Scer\HRT1 "Cele\rbx-2, Cele\rbx-1" Xtro\rnf7 "Mmus\Rbx1, Mmus\Rnf7" "Hsap\RNF7, Hsap\RBX1" embryonic stage -- adult stage organism

"viable,fertile" FBgn0053982 CG33982 - http://flybase.org/reports/FBgn0053982 protein_coding_gene - - - CG33982 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036481 CG16959 - http://flybase.org/reports/FBgn0036481 protein_coding_gene - - - "CT21630, CG16959" IPR031993:Domain of unknown function DUF4789 CG16959 11-Aug-17 DroID_v2017_08 - - - - - - DRSC10230 K -0.444727648 0.105054455 -0.277317384 0.398751476 -1.527998163 -0.208738344 FBgn0067334 sd::vg sd::vg http://flybase.org/reports/FBgn0067334 engineered_fusion_gene - - - sd::vg - - 11-Aug-17 DroID_v2017_08 - - - - - - "scutellum,thorax,macrochaeta" FBgn0029101 anon-85Cc anon-85Cc http://flybase.org/reports/FBgn0029101 gene - - - anon-85Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013473 l(1)12P2 lethal (1) 12P2 http://flybase.org/reports/FBgn0013473 - gene - - - l(1)12P2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/first instar larval cuticle,germline clone" FBgn0266711 EloC Elongin C http://flybase.org/reports/FBgn0266711 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000464223 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from genetic interaction with corto protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000464223 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from biological aspect of ancestor with PANTHER:PTN000464223 polytene chromosome interband ; GO:0005705 | inferred from direct assay Cul2-RING ubiquitin ligase complex ; GO:0031462 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay elongin complex ; GO:0070449 | inferred from direct assay "Elongin-C, CG9291, EloC, ElonginC, dElongin C, BcDNA:RH71704, l(2)SH1299, Elongin C, l(2)SH1520, l(2)SH2 1520" "IPR001232:S-phase kinase-associated protein 1-like, IPR011333:SKP1/BTB/POZ domain, IPR016073:SKP1 component, POZ domain" CG9291 11-Aug-17 DroID_v2017_08 "Drer\tceb1a, Drer\tceb1b" Scer\ELC1 "Cele\elc-2, Cele\F54F7.10, Cele\elc-1" Xtro\tceb1 Mmus\Eloc Hsap\TCEB1 FBgn0015400 kek2 kekkon-2 http://flybase.org/reports/FBgn0015400 - protein_coding_gene - negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | NOT inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CT15962, NB7, Kek2, CG4977, kek2" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013098:Immunoglobulin I-set, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype" CG4977 11-Aug-17 DroID_v2017_08 "Drer\lrtm2a, Drer\lgi1a, Drer\lrtm1, Drer\lrrc38a, Drer\si:ch1073-303k11.2, Drer\lrit1b, Drer\lrrc38b, Drer\LOC564748, Drer\islr2, Drer\lrit2, Drer\si:dkey-52j6.3, Drer\lrit3a, Drer\lrrc24, Drer\slitrk3b, Drer\lrtm2b, Drer\slitrk5b, Drer\lrit1a, Drer\lrit3b, Drer\LOC101882074, Drer\slitrk6" - "Cele\pxn-1, Cele\slt-1, Cele\iglr-3" "Xtro\lrtm2, Xtro\lrit2, Xtro\flrt1, Xtro\lrrc52, Xtro\flrt3, Xtro\slitrk6, Xtro\slitrk2, Xtro\lrit3, Xtro\lrrc3, Xtro\slitrk1, Xtro\vasn, Xtro\islr2, Xtro\lrrc15, Xtro\lrrc24, Xtro\slitrk3" "Mmus\Lrrn4cl, Mmus\Lrtm2, Mmus\Lrrc24, Mmus\Islr, Mmus\Slitrk1, Mmus\Lrrc17, Mmus\Lrit3, Mmus\Slitrk6, Mmus\Lrit1, Mmus\Lrrc55, Mmus\Slitrk2, Mmus\Lrrc26, Mmus\Lrrn4, Mmus\Lrit2, Mmus\Slitrk5, Mmus\Lrrc38, Mmus\Slitrk3, Mmus\Slitrk4, Mmus\Lrtm1, Mmus\Islr2, Mmus\Lrrc52, Mmus\Nepn, Mmus\Flrt1, Mmus\Flrt3, Mmus\Ntrk2" "Hsap\LRRC17, Hsap\AMIGO2, Hsap\LRIT1, Hsap\LRTM1, Hsap\LRTM2, Hsap\ISLR2, Hsap\LRRC38, Hsap\AMIGO3, Hsap\LRRN4, Hsap\LRIT2, Hsap\SLITRK3, Hsap\LRRN4CL, Hsap\ISLR, Hsap\FLRT3, Hsap\LGI4, Hsap\FLRT1, Hsap\LRRC55, Hsap\LRRC24, Hsap\SLITRK5, Hsap\SLITRK6, Hsap\AMIGO1, Hsap\SLITRK2, Hsap\LRRC3, Hsap\LRRC26, Hsap\LRRC52, Hsap\LRIT3" " embryonic stage , embryonic stage | stage 11 " " central nervous system | restricted

, head | lateral

, ventral midline | precursor

, ventral midline

, embryonic peripheral nervous system

" "viable,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" FBgn0259626 B1506 - http://flybase.org/reports/FBgn0259626 gene - - - B1506 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0263905 l(3)ML72 - http://flybase.org/reports/FBgn0263905 gene - - - l(3)ML72 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0024568 l(3)L7012 lethal (3) L7012 http://flybase.org/reports/FBgn0024568 - gene - - - l(3)L7012 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259705 CG42359 - http://flybase.org/reports/FBgn0259705 protein_coding_gene - vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from electronic annotation with InterPro:IPR019013 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype - "CG5558, CG42359" IPR019013:Vacuolar ATPase assembly integral membrane protein Vma21 CG42359 11-Aug-17 DroID_v2017_08 "Drer\vma21, Drer\nsun5" Scer\VMA21 "Cele\pdcd-2, Cele\R07E5.7, Cele\nsun-5" Xtro\nsun5 "Mmus\Vma21, Mmus\Nsun5" Hsap\VMA21 FBgn0005061 fs(2)OW107 female sterile (2) OW107 http://flybase.org/reports/FBgn0005061 - gene - - - fs(2)OW107 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034140 Lst Limostatin http://flybase.org/reports/FBgn0034140 protein_coding_gene - cellular response to starvation ; GO:0009267 | inferred from expression pattern regulation of calcium-mediated signaling ; GO:0050848 | inferred from direct assay negative regulation of peptide hormone secretion ; GO:0090278 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype cellular response to carbohydrate stimulus ; GO:0071322 | inferred from expression pattern glucose homeostasis ; GO:0042593 | inferred from mutant phenotype - "CG8317, Lst, lst" - CG8317 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031495 GABPI beta4GalNAcTB pilot http://flybase.org/reports/FBgn0031495 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG17257, GABPI" "IPR001594:Palmitoyltransferase, DHHC domain" CG17257 11-Aug-17 DroID_v2017_08 "Drer\zdhhc9, Drer\zgc:77880, Drer\zdhhc3b, Drer\zdhhc12b, Drer\zdhhc1, Drer\zdhhc8b, Drer\zdhhc18a, Drer\zdhhc24, Drer\zdhhc22, Drer\zdhhc12a, Drer\zdhhc5b, Drer\zdhhc3a, Drer\zdhhc14, Drer\zdhhc7, Drer\LOC100334198, Drer\zdhhc4, Drer\zdhhc23b, Drer\zdhhc5a, Drer\zdhhc21, Drer\zdhhc23a" "Scer\ERF2, Scer\PFA5, Scer\PFA4, Scer\SWF1" "Cele\dhhc-5, Cele\dhhc-12, Cele\dhhc-8, Cele\dhhc-11" "Xtro\zdhhc21, Xtro\zdhhc23, Xtro\zdhhc9, Xtro\zdhhc12, Xtro\zdhhc14, Xtro\zdhhc3, Xtro\dnz1, Xtro\zdhhc24, Xtro\zdhhc8, Xtro\zdhhc1, Xtro\zdhhc7" "Mmus\Zdhhc8, Mmus\Zdhhc11, Mmus\Zdhhc24, Mmus\Zdhhc22, Mmus\Zdhhc23, Mmus\Zdhhc7, Mmus\Zdhhc18, Mmus\Zdhhc25, Mmus\Zdhhc12, Mmus\Zdhhc19, Mmus\Zdhhc1, Mmus\Zdhhc3, Mmus\Zdhhc4, Mmus\Zdhhc5, Mmus\Zdhhc9, Mmus\Zdhhc14, Mmus\Zdhhc21" "Hsap\ZDHHC12, Hsap\ZDHHC3, Hsap\ZDHHC11, Hsap\ZDHHC5, Hsap\ZDHHC1, Hsap\ZDHHC19, Hsap\ZDHHC18, Hsap\ZDHHC8, Hsap\ZDHHC21, Hsap\ZDHHC4, Hsap\ZDHHC24, Hsap\ZDHHC23, Hsap\ZDHHC9, Hsap\ZDHHC22, Hsap\ZDHHC7, Hsap\ZDHHC14" "viable,fertile" FBgn0026254 dali dali http://flybase.org/reports/FBgn0026254 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available dali - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001256 ImpL1 Ecdysone-inducible gene L1 http://flybase.org/reports/FBgn0001256 - protein_coding_gene - - - "Imp-L1, IMP-L1, CG10717, ImpL1" "IPR002350:Kazal domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG10717 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034143 CG8303 - http://flybase.org/reports/FBgn0034143 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 long-chain-fatty-acyl-CoA reductase activity ; GO:0050062 | inferred from sequence or structural similarity with UniProtKB:Q922J9 wax biosynthetic process ; GO:0010025 | inferred from sequence or structural similarity with UniProtKB:Q922J9 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with UniProtKB:Q922J9 CG8303 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG8303 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" - "Cele\C32D5.12, Cele\fard-1" Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR2, Hsap\FAR1" lethal FBgn0058371 CG40371 - http://flybase.org/reports/FBgn0058371 protein_coding_gene - - - CG40371 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011102 l(1)Q63a lethal (1) Q63a http://flybase.org/reports/FBgn0011102 FBgn0010210 gene - - - l(1)Q63a - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259712 CG42366 - http://flybase.org/reports/FBgn0259712 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with HGNC:6816 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000622192" regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 intraciliary transport ; GO:0042073 | inferred from biological aspect of ancestor with PANTHER:PTN001172286 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:6816 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN001172286 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN001172286 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 "CG31711, CG42366, MAK, IME2, CG31878, CG4588" "IPR017441:Protein kinase, ATP binding site, IPR011009:Protein kinase-like domain, IPR008271:Serine/threonine-protein kinase, active site, IPR000719:Protein kinase domain" CG42366 11-Aug-17 DroID_v2017_08 Drer\mak Scer\IME2 "Cele\F52B5.2, Cele\dyf-5" "Xtro\ick, Xtro\mak" "Mmus\Ick, Mmus\Mak, Mmus\Mok" "Hsap\ICK, Hsap\MOK, Hsap\MAK" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC02760 E 0.288562064 0.159423627 0.019319352 -3.056357154 -0.798472665 0.102270046 FBgn0051730 CG31730 - http://flybase.org/reports/FBgn0051730 protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from biological aspect of ancestor with PANTHER:PTN000558065 N-terminal peptidyl-methionine acetylation ; GO:0017196 | inferred from biological aspect of ancestor with PANTHER:PTN000558099 NatB complex ; GO:0031416 | inferred from biological aspect of ancestor with PANTHER:PTN000558099 CG31730 "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG31730 11-Aug-17 DroID_v2017_08 Drer\naa20 "Scer\ARD1, Scer\NAT3" "Cele\daf-31, Cele\Y97E10AL.3" - Mmus\Naa20 "Hsap\NAA20, Hsap\NAA11" "viable,fertile" FBgn0005503 l(2)24EFa lethal (2) 24EFa http://flybase.org/reports/FBgn0005503 - gene - - - "l(2)Gr.I, l(2)24EFa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034083 lbk lambik http://flybase.org/reports/FBgn0034083 protein_coding_gene - - - "Lbk, CG8434, lbk" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR032675:Leucine-rich repeat domain, L domain-like, IPR013098:Immunoglobulin I-set" CG8434 11-Aug-17 DroID_v2017_08 "Drer\lrig1, Drer\lgi1a, Drer\lgi2a, Drer\lgi2b, Drer\lrig2, Drer\lrig3, Drer\rtn4rl2a, Drer\rtn4rl2b, Drer\lgi3, Drer\lgi1b, Drer\igdcc3" - "Cele\sma-10, Cele\iglr-1, Cele\iglr-2" "Xtro\lrig2, Xtro\lrig1, Xtro\lrig3" "Mmus\Lrig1, Mmus\Lgi2, Mmus\Lgi4, Mmus\Lrig2, Mmus\Lgi1, Mmus\Lrrtm2, Mmus\Lrig3, Mmus\Lgi3" "Hsap\LRIG1, Hsap\LGI3, Hsap\LRIG2, Hsap\LGI2, Hsap\LRRTM2, Hsap\LGI1, Hsap\LRIG3, Hsap\LGI4" viable DRSC07178 K 0.638826181 0.216452907 0.420278945 -0.086333741 2.289477171 0.91865363 FBgn0004080 Ars-region15 Autonomous replicating sequence region 15 http://flybase.org/reports/FBgn0004080 - region - - - "Ars-region15, Ars15" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259454 C279 - http://flybase.org/reports/FBgn0259454 gene - - - C279 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing vein L3,wing" FBgn0001510 l(1)10Fd lethal (1) 10Fd http://flybase.org/reports/FBgn0001510 - gene - - - "10, l(1)L10, l(1)10Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003175 px plexus http://flybase.org/reports/FBgn0003175 "FBgn0022042, FBgn0022054" protein_coding_gene - imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype nuclear matrix ; GO:0016363 | inferred from direct assay "l(2)k08316, l(2)k08134, CG4444, px" "IPR011989:Armadillo-like helical, IPR000286:Histone deacetylase superfamily" CG4444 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage && larval stage larval stage | third instar dorsal mesothoracic disc

"behavior defective,recessive,lethal,viable,fertile,visible,wild-type,somatic clone" "wing,wing vein,ectopic,eye,leg,somatic clone" FBgn0262689 CR43159 - http://flybase.org/reports/FBgn0262689 non_protein_coding_gene - - - CR43159 - CR43159 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020899 Su(osk)D20 Suppressor of oskar D20 http://flybase.org/reports/FBgn0020899 - gene - - - "D20, Su(osk)D20" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267787 CR46118 - http://flybase.org/reports/FBgn0267787 non_protein_coding_gene - - - CR46118 - CR46118 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038309 Amt Ammonium transporter http://flybase.org/reports/FBgn0038309 protein_coding_gene ammonium transmembrane transporter activity ; GO:0008519 | inferred from biological aspect of ancestor with PANTHER:PTN000198157 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype cellular response to ammonia ; GO:1903718 | inferred from mutant phenotype ammonium transmembrane transport ; GO:0072488 | inferred from biological aspect of ancestor with PANTHER:PTN000198157 organic cation transport ; GO:0015695 | inferred from biological aspect of ancestor with PANTHER:PTN000198157 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000198157 "Amt, CG6499" "IPR001905:Ammonium transporter, IPR024041:Ammonium transporter AmtB-like domain" CG6499 11-Aug-17 DroID_v2017_08 Drer\rhcgb "Scer\MEP1, Scer\MEP2, Scer\MEP3" "Cele\amt-4, Cele\amt-1, Cele\amt-2, Cele\amt-3" "Xtro\rhcg, Xtro\rhbg" Mmus\Rhcg - "lethal,auditory perception defective,viable" FBgn0005487 l(1)ts1808 lethal (1) ts1808 http://flybase.org/reports/FBgn0005487 - gene - - - l(1)ts1808 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0014400 trimmed trimmed http://flybase.org/reports/FBgn0014400 - gene - - - trimmed - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027197 l(2)30Ca lethal (2) 30Ca http://flybase.org/reports/FBgn0027197 - gene - - - l(2)30Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005347 semi-f semi-forked http://flybase.org/reports/FBgn0005347 - gene - - - semi-f - - 11-Aug-17 DroID_v2017_08 - - - - - - macrochaeta FBgn0266390 CR45030 - http://flybase.org/reports/FBgn0266390 non_protein_coding_gene - - - CR45030 - CR45030 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060614 l(3)S089904 lethal (3) S089904 http://flybase.org/reports/FBgn0060614 gene - - - "0899/04, l(3)S089904" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0002771 ml minute-like http://flybase.org/reports/FBgn0002771 - gene - - - "sb, ml" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,recessive,viable,reduced,visible,male fertile,female fertile,body color defective" "macrochaeta,trident,wing,wing vein,adult abdomen,female" FBgn0266999 alpha-Cat::ed - http://flybase.org/reports/FBgn0266999 engineered_fusion_gene - - - "Ed::alphaCat, alpha-Cat::ed" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267455 CR45805 - http://flybase.org/reports/FBgn0267455 non_protein_coding_gene - - - CR45805 - CR45805 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033272 RagC-D Ras-related GTP binding C/D http://flybase.org/reports/FBgn0033272 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006762 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with RagA-B GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000003395 positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype cellular response to amino acid stimulus ; GO:0071230 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Gtr2, CG8707, dRagC, RagC-D, RagC, ragC" "IPR006762:Gtr1/RagA G protein, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8707 11-Aug-17 DroID_v2017_08 "Drer\rragd, Drer\rragca, Drer\rragcb" Scer\GTR2 Cele\ragc-1 "Xtro\rragc, Xtro\rragd" "Mmus\Rragc, Mmus\Rragd" "Hsap\RRAGD, Hsap\RRAGC" "lethal - all die before end of larval stage,some die during third instar larval stage,size defective,decreased cell number,increased cell number,viable" wing FBgn0060745 l(3)S066003 lethal (3) S066003 http://flybase.org/reports/FBgn0060745 gene - - - "0660/03, l(3)S066003" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086898 dgo diego http://flybase.org/reports/FBgn0086898 protein_coding_gene - establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement establishment of planar polarity ; GO:0001736 | traceable author statement establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype cytoplasm ; GO:0005737 | traceable author statement "Dgo, dgo, CG12342, EP(2)2619, EP2619" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG12342 11-Aug-17 DroID_v2017_08 "Drer\ankrd6b, Drer\ankrd6a" - - "Xtro\anks3, Xtro\ankrd6" "Mmus\Uaca, Mmus\Ankrd35, Mmus\Rai14, Mmus\Ankrd6" "Hsap\ANKRD62, Hsap\ANKRD18B, Hsap\ANKRD6, Hsap\ANKRD26, Hsap\ANKRD18A, Hsap\ANKRD20A1, Hsap\ANKRD30B, Hsap\ANKRD36C, Hsap\CCDC144A, Hsap\ANKRD20A3, Hsap\POTEC, Hsap\ANKRD20A2, Hsap\ANKRD36B, Hsap\FPGT-TNNI3K, Hsap\ANKRD30A, Hsap\ANKRD20A4" DRSC26782 K -0.511511798 0.036467439 0.341789282 0.495235947 0.554868121 1.728533291 FBgn0016763 anon-12Da anon-12Da http://flybase.org/reports/FBgn0016763 - gene - - - anon-12Da - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046643 anon-38D.24 anon-38D.24 http://flybase.org/reports/FBgn0046643 gene - - - "38D.24, anon-38D.24" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033738 DUBAI Deubiquitinating apoptotic inhibitor http://flybase.org/reports/FBgn0033738 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Diap1 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:20067 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:20067 negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype negative regulation of proteolysis involved in cellular protein catabolic process ; GO:1903051 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG8830, DUBAI, Usp38, Q7JQI1" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR033840:Ubiquitin-specific peptidase 38, IPR028889:Ubiquitin specific protease domain" CG8830 11-Aug-17 DroID_v2017_08 "Drer\usp38, Drer\usp46, Drer\usp12a, Drer\usp1, Drer\usp12b" "Scer\UBP13, Scer\UBP9, Scer\RAD7, Scer\UBP11" - "Xtro\usp35, Xtro\hapln3, Xtro\usp1, Xtro\usp46" "Mmus\Usp38, Mmus\Usp35, Mmus\Usp46, Mmus\Usp1, Mmus\Usp12" "Hsap\USP35, Hsap\USP12, Hsap\USP1, Hsap\USP46, Hsap\USP38" "partially lethal - majority die,some die during pupal stage,locomotor behavior defective,visible" eye DRSC05344 K -0.159364607 -0.770071296 0.379912624 0.36133127 1.530879844 -0.314619114 FBgn0259683 Ir40a Ionotropic receptor 40a http://flybase.org/reports/FBgn0259683 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir40a, CG42352, IR40a, CG5922, CG5929, DmelIR40a" IPR001320:Ionotropic glutamate receptor CG42352 11-Aug-17 DroID_v2017_08 - - Cele\glr-2 - - - FBgn0043978 Su(tor)307-14 Su(tor)307-14 http://flybase.org/reports/FBgn0043978 gene - - - "307-14, Su(tor)307-14" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029827 CG6048 - http://flybase.org/reports/FBgn0029827 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model" - "SP108, CG6048" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG6048 11-Aug-17 DroID_v2017_08 Drer\si:ch211-165b19.8 - Cele\try-1 Xtro\gzmh "Mmus\Klk11, Mmus\Habp2, Mmus\Gzmk, Mmus\Cfd, Mmus\Egfbp2" "Hsap\KLK14, Hsap\CFD, Hsap\KLK10, Hsap\AZU1, Hsap\HABP2, Hsap\PRSS55" "viable,visible" trichogen cell FBgn0052768 CR32768 - http://flybase.org/reports/FBgn0052768 non_protein_coding_gene - - - CR32768 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0277434 v(2)k14204 - http://flybase.org/reports/FBgn0277434 gene - - - "v(2)k14204, l(2)k14204" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022339 brls barrels http://flybase.org/reports/FBgn0022339 - gene - - - brls - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033382 Hydr1 alpha/beta hydrolase 1 http://flybase.org/reports/FBgn0033382 protein_coding_gene lipase activity ; GO:0016298 | inferred from biological aspect of ancestor with PANTHER:PTN000846579 lipase activity ; GO:0016298 | inferred from sequence alignment with Hydr2 cellular lipid metabolic process ; GO:0044255 | inferred from biological aspect of ancestor with PANTHER:PTN000082644 lipid metabolic process ; GO:0006629 | inferred from sequence alignment with Hydr2 cellular_component ; GO:0005575 | no biological data available "Hydr1, CG8058, Dm.HYDR1" "IPR000073:Alpha/beta hydrolase fold-1, IPR000952:AB hydrolase 4, conserved site, IPR012020:AB hydrolase 4 family, IPR029058:Alpha/Beta hydrolase fold" CG8058 11-Aug-17 DroID_v2017_08 "Drer\abhd2b, Drer\abhd3, Drer\abhd2a" "Scer\EHT1, Scer\EEB1, Scer\YMR210W" "Cele\abhd-3.2, Cele\abhd-3.1" "Xtro\abhd2, Xtro\abhd3" "Mmus\Abhd3, Mmus\Abhd2, Mmus\Abhd1, Mmus\Abhd15" "Hsap\ABHD2, Hsap\ABHD3, Hsap\ABHD1" viable FBgn0036406 CG13484 - http://flybase.org/reports/FBgn0036406 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13484 IPR028265:M-phase-specific PLK1-interacting protein-like CG13484 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially lethal - majority die,some die during pupal stage" FBgn0014316 l(3)ry125a lethal (3) ry125a http://flybase.org/reports/FBgn0014316 - gene - - - l(3)ry125a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260121 2L0419 - http://flybase.org/reports/FBgn0260121 gene - - - 2L0419 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "imaginal tracheoblast,somatic clone,embryonic/larval tracheal system" FBgn0053265 Muc68E Mucin 68E http://flybase.org/reports/FBgn0053265 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "Muc68E, CG33265" IPR002557:Chitin binding domain CG33265 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-160p18.3, Drer\asic2, Drer\otogl, Drer\scospondin, Drer\si:ch73-215d9.1, Drer\scel, Drer\vwf, Drer\znf512, Drer\LOC799643" "Scer\YIL169C, Scer\PRM7, Scer\HKR1, Scer\FLO5, Scer\HPF1, Scer\FLO11, Scer\YMR317W, Scer\MSB2, Scer\YFR016C, Scer\FLO1, Scer\FLO9, Scer\FIG2" "Cele\dpy-6, Cele\H02F09.3, Cele\dct-9, Cele\srap-1, Cele\F35C5.3, Cele\ZC178.2, Cele\clec-223, Cele\cbd-1, Cele\H43E16.1" "Xtro\cd44, Xtro\map4, Xtro\impg1" "Mmus\Vcan, Mmus\Muc5b, Mmus\Sspo, Mmus\Muc4, Mmus\Muc6, Mmus\Vwf, Mmus\Muc5ac, Mmus\Muc2, Mmus\Rtn4, Mmus\Impg2, Mmus\Zfp512, Mmus\Impg1, Mmus\3632451O06Rik, Mmus\Zfp512b, Mmus\Cd44" "Hsap\ZNF512B, Hsap\IMPG2, Hsap\CD44, Hsap\SSPO, Hsap\MUC4, Hsap\OTOG, Hsap\C14orf37, Hsap\MUC6, Hsap\VWF, Hsap\MUC7, Hsap\MUC2, Hsap\MUC19, Hsap\IMPG1, Hsap\ZNF512, Hsap\RTN4, Hsap\MUC16, Hsap\VCAN, Hsap\MUC5B, Hsap\MUC1, Hsap\MUC17" viable DRSC26478 K 0.258517227 0.189358634 0.100124451 0.181165564 1.686202656 -0.207944779 FBgn0034631 TAF1C-like TATA box-binding protein-associated factor RNA polymerase I subunit C-like http://flybase.org/reports/FBgn0034631 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter ; GO:1901838 | inferred by curator from GO:0005668 RNA polymerase transcription factor SL1 complex ; GO:0005668 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "CG10496, TAF1C-like" IPR015943:WD40/YVTN repeat-like-containing domain CG10496 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069066 4B7-11 4B7-11 http://flybase.org/reports/FBgn0069066 gene molecular_function ; GO:0003674 | no biological data available germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 4B7-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,germline clone" FBgn0277425 l(3)psg22 - http://flybase.org/reports/FBgn0277425 gene - - - "l(3)psg22, psg22" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004010 wgo wings out http://flybase.org/reports/FBgn0004010 - gene - - - wgo - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0037540 Pbp95 PSEA-binding protein 95kD http://flybase.org/reports/FBgn0037540 protein_coding_gene "bent DNA binding ; GO:0003681 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Pbp45 transcription factor activity, RNA polymerase II transcription factor recruiting ; GO:0001135 | inferred from biological aspect of ancestor with PANTHER:PTN000067606 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000067606 DNA binding ; GO:0003677 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000067606" snRNA transcription from RNA polymerase II promoter ; GO:0042795 | inferred from direct assay snRNA transcription from RNA polymerase III promoter ; GO:0042796 | inferred from direct assay protein-DNA complex assembly ; GO:0065004 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000067606 snRNA-activating protein complex ; GO:0019185 | inferred from physical interaction with Pbp45 inferred from physical interaction with Pbp49 snRNA-activating protein complex ; GO:0019185 | inferred from direct assay "BEST:LD28511, anon-WO0118547.359, Pbp95, DmSNAP190, DmPBP95, CG2702, DmPBP, DmSNAPc" "IPR001005:SANT/Myb domain, IPR009057:Homeobox domain-like, IPR017877:Myb-like domain, IPR017930:Myb domain" CG2702 11-Aug-17 DroID_v2017_08 "Drer\mybl2a, Drer\snapc4, Drer\mybl1, Drer\myb, Drer\dmtf1" "Scer\REB1, Scer\NSI1, Scer\BAS1" Cele\snpc-4 "Xtro\mybl2, Xtro\snapc4, Xtro\myb" "Mmus\Snapc4, Mmus\4932411N23Rik, Mmus\Mybl1, Mmus\Myb, Mmus\Dmtf1, Mmus\Mybl2" "Hsap\MYBL2, Hsap\SNAPC4, Hsap\DMTF1, Hsap\MYBL1, Hsap\MYB" "viable,visible" "chaeta,mesothoracic tergum" FBgn0029142 P(3)91F P(3)91F http://flybase.org/reports/FBgn0029142 gene - - - P(3)91F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065875 l(2)SH0245 lethal (2) SH0245 http://flybase.org/reports/FBgn0065875 gene - - - "l(2)SH0245, l(2)SH2 0245" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022129 l(2)k06409 lethal (2) k06409 http://flybase.org/reports/FBgn0022129 - gene - - - l(2)k06409 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033818 CG4712 - http://flybase.org/reports/FBgn0033818 protein_coding_gene - - - CG4712 IPR025254:Domain of unknown function DUF4201 CG4712 11-Aug-17 DroID_v2017_08 - - - - Mmus\Ccdc96 - viable FBgn0067324 B71 B71 http://flybase.org/reports/FBgn0067324 gene - - - B71 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,viable" chaeta FBgn0044067 GATE\polyprotein GATE element polyprotein http://flybase.org/reports/FBgn0044067 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 - - GATE\polyprotein "IPR008737:Peptidase aspartic, putative, IPR008042:Retrotransposon, Pao, IPR012337:Ribonuclease H-like domain, IPR005312:Protein of unknown function DUF1759, IPR015416:Zinc finger, H2C2-type, histone UAS binding" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045847 mdg1\ORF1 mdg1 element ORF1 http://flybase.org/reports/FBgn0045847 transposable_element_gene - - - mdg1\ORF1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020864 cd-s cardinal-similis http://flybase.org/reports/FBgn0020864 - gene - - - cd-s - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036887 CG9231 - http://flybase.org/reports/FBgn0036887 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of pain ; GO:0019233 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG9231 IPR009432:Protein of unknown function DUF1075 CG9231 11-Aug-17 DroID_v2017_08 Drer\fam162a - Cele\M05D6.6 Xtro\fam162a "Mmus\Fam162a, Mmus\Fam162b" "Hsap\FAM162B, Hsap\FAM162A" viable FBgn0019677 mor(1)2 mortality gene (1)2 http://flybase.org/reports/FBgn0019677 - gene - - - mor(1)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0035331 MsR1 Myosuppressin receptor 1 http://flybase.org/reports/FBgn0035331 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from sequence model myosuppressin receptor activity ; GO:0035013 | inferred from physical interaction with Ms G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity myosuppressin receptor activity ; GO:0035013 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ; GO:0007193 | inferred from direct assay adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay "CG8985, DMSR-1, anon-WO0170980.107, anon-WO0170980.106, DmsR-1, Dm CG8985, DmsR, MsR1, DMS-R1, MS-R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM, IPR019427:7TM GPCR, serpentine receptor class w (Srw)" CG8985 11-Aug-17 DroID_v2017_08 "Drer\gper1, Drer\gpr142" - "Cele\srw-82, Cele\srw-145, Cele\srw-43, Cele\srw-123, Cele\srw-115, Cele\dmsr-10, Cele\srw-139, Cele\srw-108, Cele\srw-143, Cele\srw-113, Cele\srw-11, Cele\C41G6.16, Cele\srw-40, Cele\dmsr-15, Cele\srw-102, Cele\srw-76, Cele\srw-88, Cele\srw-8, Cele\dmsr-5, Cele\srw-84, Cele\srw-100, Cele\srw-4, Cele\frpr-13, Cele\srw-30, Cele\C25F9.13, Cele\srw-61, Cele\srw-79, Cele\srw-15, Cele\srw-136, Cele\F38E1.6, Cele\srw-98, Cele\srw-140, Cele\srw-9, Cele\T26H8.5, Cele\srw-41, Cele\dmsr-6, Cele\srw-124, Cele\srw-69, Cele\srw-22, Cele\dmsr-11, Cele\srw-57, Cele\srw-130, Cele\srw-121, Cele\srw-39, Cele\frpr-7, Cele\srw-21, Cele\dmsr-4, Cele\F13H6.5, Cele\srw-13, Cele\srw-103, Cele\srw-141, Cele\dmsr-14, Cele\srw-75, Cele\srw-144, Cele\srw-117, Cele\srw-137, Cele\srw-77, Cele\srw-67, Cele\srw-35, Cele\srw-7, Cele\srw-87, Cele\srw-2, Cele\srw-68, Cele\srw-97, Cele\sprr-3, Cele\srw-89, Cele\egl-6, Cele\srw-112, Cele\srw-66, Cele\srw-20, Cele\srw-51, Cele\dmsr-3, Cele\srw-118, Cele\Y70C5A.4, Cele\srw-29, Cele\srw-62, Cele\srw-23, Cele\dmsr-13, Cele\srw-83, Cele\srw-32, Cele\srw-119, Cele\srw-19, Cele\srw-54, Cele\Y75B12B.10, Cele\srw-60, Cele\srw-34, Cele\dmsr-2, Cele\srw-24, Cele\srw-95, Cele\M01G12.6, Cele\srw-53, Cele\srw-33, Cele\srw-31, Cele\srw-17, Cele\srw-42, Cele\dmsr-8, Cele\srw-85, Cele\srw-12, Cele\srw-73, Cele\srw-56, Cele\srw-99, Cele\srw-138, Cele\srw-133, Cele\srw-111, Cele\srw-48, Cele\srw-107, Cele\srw-6, Cele\dmsr-16, Cele\srw-26, Cele\K01A6.6, Cele\srw-10, Cele\srw-3, Cele\srw-127, Cele\srw-134, Cele\srw-63, Cele\srw-94, Cele\srw-90, Cele\dmsr-12, Cele\srw-72, Cele\srw-122, Cele\dmsr-9, Cele\srw-55, Cele\T02D1.4, Cele\srw-120, Cele\srw-101, Cele\dmsr-7, Cele\srw-59, Cele\srw-44, Cele\dmsr-1, Cele\T27C5.10, Cele\F09C6.16, Cele\T26H8.4, Cele\srw-142, Cele\srw-38, Cele\srw-16, Cele\srw-14, Cele\srw-1, Cele\C47E8.3, Cele\C09F12.3, Cele\srw-91, Cele\srw-71, Cele\srw-36, Cele\M03F8.7, Cele\srw-129, Cele\srw-109" - "Mmus\Gpr139, Mmus\Gpr142" "Hsap\GPR139, Hsap\GPR142" "viable,partially lethal - majority die,visible,locomotor behavior defective" wing FBgn0052686 CG32686 - http://flybase.org/reports/FBgn0052686 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT25933, anon-WO02059370.11, CG32686" - CG32686 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030992 CG33253 - http://flybase.org/reports/FBgn0030992 protein_coding_gene molecular_function ; GO:0003674 | no biological data available phagocytosis ; GO:0006909 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001972 "CG7633, CK01423, BEST:CK01423, CG14192, CG33253" "IPR001107:Band 7 domain, IPR018080:Band 7/stomatin-like, conserved site, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001972:Stomatin family" CG33253 11-Aug-17 DroID_v2017_08 "Drer\nphs2, Drer\stoml1, Drer\stom, Drer\stoml2, Drer\stoml3b, Drer\zgc:112408, Drer\stoml3a" - "Cele\sto-4, Cele\unc-1, Cele\stl-1, Cele\sto-6, Cele\sto-1, Cele\sto-3, Cele\sto-2, Cele\mec-2, Cele\sto-5, Cele\unc-24" "Xtro\stoml1, Xtro\stoml3" "Mmus\Stoml1, Mmus\Nphs2, Mmus\Stom, Mmus\Stoml2, Mmus\Stoml3" "Hsap\STOML1, Hsap\NPHS2, Hsap\STOML2, Hsap\STOM, Hsap\STOML3" viable DRSC20053 K -0.060614417 0.264020846 0.466298821 -0.098678709 1.620241662 0.119299867 FBgn0031432 Cyp309a1 Cyp309a1 http://flybase.org/reports/FBgn0031432 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" - "309a1, CG9964, Cyp309a1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG9964 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\tbxas1, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp3c2, Drer\cyp3c4" "Scer\ERG11, Scer\DIT2" "Cele\cyp-25A2, Cele\cyp-13A8, Cele\cyp-13A4, Cele\cyp-25A3, Cele\cyp-13B2, Cele\cyp-13A1, Cele\cyp-25A1, Cele\cyp-13A12, Cele\cyp-25A6, Cele\cyp-13A10, Cele\cyp-13A3, Cele\cyp-13A11, Cele\cyp-43A1, Cele\cyp-13A7, Cele\cyp-44A1, Cele\cyp-25A4, Cele\cyp-13A6, Cele\cyp-13B1, Cele\cyp-13A5, Cele\cyp-13A2" "Xtro\tbxas1, Xtro\LOC100494419, Xtro\cyp3a4, Xtro\cyp3a5" "Mmus\Cyp3a25, Mmus\Cyp3a57, Mmus\Cyp3a13, Mmus\Tbxas1, Mmus\Cyp3a11, Mmus\Cyp3a41b, Mmus\Cyp3a44, Mmus\Cyp3a16, Mmus\Cyp3a41a, Mmus\Cyp3a59" "Hsap\CYP3A43, Hsap\CYP3A5, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A7, Hsap\TBXAS1, Hsap\CYP3A4" "lethal,viable,visible" "eye,chaeta,supernumerary" FBgn0033610 CG18335 - http://flybase.org/reports/FBgn0033610 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18335 IPR018902:Uncharacterised protein family UPF0573/UPF0605 CG18335 11-Aug-17 DroID_v2017_08 Drer\fam166b - "Cele\F49C5.10, Cele\T09D3.8" Xtro\fam166b "Mmus\Fam166b, Mmus\Fam166a" "Hsap\FAM166B, Hsap\FAM166A" FBgn0065239 l(2)SH2160 lethal (2) SH2160 http://flybase.org/reports/FBgn0065239 gene - - - "l(2)SH2160, l(2)SH2 2160" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026675 l(1)G0113 lethal (1) G0113 http://flybase.org/reports/FBgn0026675 - gene - - - l(1)G0113 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028020 l(3)S104103 lethal (3) S104103 http://flybase.org/reports/FBgn0028020 gene - - - "1041/03, l(3)S104103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001390 l(1)2Ca lethal (1) 2Ca http://flybase.org/reports/FBgn0001390 - gene - - - "l(1)C282, l(1)2Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028546 ics icarus http://flybase.org/reports/FBgn0028546 protein_coding_gene GTPase regulator activity ; GO:0030695 | inferred from sequence or structural similarity negative regulation of JUN kinase activity ; GO:0043508 | inferred from mutant phenotype integrin-mediated signaling pathway ; GO:0007229 | inferred from genetic interaction with stck apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with bsk inferred from genetic interaction with msn - "RSU-1, BG:BACR48E02.4, CT25926, CG9031, ics, Rsu-1, RSU1, Ics, Rsu1" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG9031 11-Aug-17 DroID_v2017_08 Drer\rsu1 - Cele\rsu-1 Xtro\rsu1 Mmus\Rsu1 Hsap\RSU1 "viable,fertile,visible,recessive" wing blade FBgn0038768 CG4936 - http://flybase.org/reports/FBgn0038768 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D negative regulation of ERK1 and ERK2 cascade ; GO:0070373 | inferred from genetic interaction with Ras85D nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG4936 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG4936 11-Aug-17 DroID_v2017_08 "Drer\LOC103910994, Drer\si:dkey-7l6.3, Drer\si:dkey-210j14.3, Drer\wt1a, Drer\si:ch211-89o9.6, Drer\wt1b, Drer\si:dkey-56e3.3" Scer\AZF1 "Cele\che-1, Cele\klf-2, Cele\blmp-1, Cele\klf-3, Cele\unc-98, Cele\hinf-1, Cele\klu-2" "Xtro\znf420, Xtro\znf160, Xtro\zbtb34" "Mmus\Zfp612, Mmus\Zkscan1, Mmus\Zbtb20, Mmus\Zfp174, Mmus\Zfp113, Mmus\Zkscan6, Mmus\Mzf1, Mmus\Zfp92, Mmus\Zkscan17, Mmus\Zfp444, Mmus\Zfp984, Mmus\Zfp809, Mmus\Zfp352, Mmus\Zscan21, Mmus\Klf1, Mmus\Zfp263, Mmus\Gm3604, Mmus\Zscan12, Mmus\Zfp202, Mmus\Zfp758, Mmus\Zfp111, Mmus\Zfp558, Mmus\E430018J23Rik, Mmus\Zkscan16, Mmus\Zfp566, Mmus\Zscan25, Mmus\Zbtb6, Mmus\Zscan2, Mmus\Zfp449, Mmus\Zfp945, Mmus\Wt1, Mmus\Zfp93, Mmus\Zkscan8, Mmus\Zfp708, Mmus\Zkscan5, Mmus\Zfp12, Mmus\Zkscan3, Mmus\Klf17, Mmus\Zscan26, Mmus\5730507C01Rik, Mmus\Zfp951, Mmus\Gm13212, Mmus\Zkscan4, Mmus\Zfp296, Mmus\Zfp13, Mmus\Zfp735, Mmus\Zkscan14, Mmus\Zfp51, Mmus\Zfp869, Mmus\Zscan20, Mmus\Zkscan7, Mmus\Zscan29, Mmus\Zfp397, Mmus\Zscan22, Mmus\Zfp213, Mmus\Zkscan2, Mmus\Zfp62" "Hsap\ZNF730, Hsap\ZNF792, Hsap\ZNF732, Hsap\ZSCAN2, Hsap\ZNF708, Hsap\ZNF468, Hsap\ZNF681, Hsap\ZNF852, Hsap\ZNF98, Hsap\KLF1, Hsap\ZNF28, Hsap\ZNF527, Hsap\ZNF595, Hsap\ZNF492, Hsap\ZNF611, Hsap\ZNF721, Hsap\ZNF251, Hsap\ZNF528, Hsap\ZNF761, Hsap\ZNF707, Hsap\ZNF43, Hsap\ZNF600, Hsap\ZKSCAN7, Hsap\ZNF764, Hsap\ZNF582, Hsap\ZNF572, Hsap\ZFP62, Hsap\ZNF160, Hsap\ZNF766, Hsap\ZNF675, Hsap\ZNF480, Hsap\ZNF70, Hsap\KLF17, Hsap\ZNF558, Hsap\ZNF485, Hsap\ZSCAN30, Hsap\ZFP28, Hsap\ZNF845, Hsap\ZNF211, Hsap\ZNF296, Hsap\ZNF816, Hsap\WT1, Hsap\ZNF570, Hsap\ZSCAN29, Hsap\ZNF610, Hsap\ZNF107, Hsap\ZNF785, Hsap\ZNF850, Hsap\RBAK-RBAKDN, Hsap\ZSCAN32, Hsap\ZNF623, Hsap\ZNF568, Hsap\ZBTB20, Hsap\ZNF233, Hsap\ZNF888, Hsap\ZNF117, Hsap\OSR2, Hsap\ZNF793, Hsap\ZNF394, Hsap\ZNF679, Hsap\ZNF254, Hsap\ZNF891, Hsap\ZFP37" "visible,partially lethal - majority die,some die during pupal stage,female fertile,lethal,recessive" "trichogen cell,mesothoracic tergum" DRSC15680 IK -0.998708715 1.710819521 1.086085404 1.185087604 0.729240615 1.551195212 FBgn0004156 l(2)51Dc lethal (2) 51Dc http://flybase.org/reports/FBgn0004156 - gene - - - l(2)51Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic" FBgn0010136 l(2)57 lethal (2) 57 http://flybase.org/reports/FBgn0010136 - gene - - - l(2)57 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064192 arm::Pen arm::Pen http://flybase.org/reports/FBgn0064192 engineered_fusion_gene - - - arm::Pen - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051287 CG31287 - http://flybase.org/reports/FBgn0051287 protein_coding_gene - - - "NEST:bs24f08, CG31287" - CG31287 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265147 CR44216 - http://flybase.org/reports/FBgn0265147 non_protein_coding_gene - - - "CR44216, lincRNA.131" - CR44216 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263403 CG43449 - http://flybase.org/reports/FBgn0263403 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43449, lincRNA.748" - CG43449 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033538 CG11883 - http://flybase.org/reports/FBgn0033538 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006179, InterPro:IPR008334" "nucleotide catabolic process ; GO:0009166 | inferred from electronic annotation with InterPro:IPR006179, InterPro:IPR008334" - CG11883 "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006179:5'-Nucleotidase/apyrase, IPR008334:5'-Nucleotidase, C-terminal, IPR029052:Metallo-dependent phosphatase-like" CG11883 11-Aug-17 DroID_v2017_08 Drer\nt5e "Scer\YHR202W, Scer\DIG1" "Cele\Y39B6A.30, Cele\Y39B6A.18, Cele\Y80D3A.8, Cele\ZK262.4, Cele\Y51A2B.6" Xtro\nt5e "Mmus\Nt5e, Mmus\4933425L06Rik" "Hsap\NT5E, Hsap\GOLM1" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0015303 Su(SD)3BPi Suppressor of SD 3BPi http://flybase.org/reports/FBgn0015303 - gene - - - Su(SD)3BPi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032336 AstC Allatostatin C http://flybase.org/reports/FBgn0032336 protein_coding_gene hormone activity ; GO:0005179 | inferred from sequence or structural similarity with UniProtKB:P42559 neuropeptide hormone activity ; GO:0005184 | non-traceable author statement hormone activity ; GO:0005179 | non-traceable author statement myoinhibitory hormone activity ; GO:0016085 | inferred from direct assay negative regulation of juvenile hormone biosynthetic process ; GO:0045968 | inferred from sequence or structural similarity with UniProtKB:P42559 neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement negative regulation of juvenile hormone biosynthetic process ; GO:0045968 | NOT non-traceable author statement regulation of heart contraction ; GO:0008016 | inferred from direct assay negative regulation of heart rate ; GO:0010459 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG14919, AstC, Ast2, DAP-C, flt, FLT, M-ASH, Drm-AST-C, gh06087, BEST:GH06087, BcDNA:RH36507, ast2, AST-C, Ast-C, ASTC, CG149199, ASC, Flt" "IPR020161:Allatostatin, insect" CG14919 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259701 CG42355 - http://flybase.org/reports/FBgn0259701 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sperm chromatin condensation ; GO:0035092 | inferred from electronic annotation with InterPro:IPR024460 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32308, CG42355" "IPR009071:High mobility group box domain, IPR024460:Protamine-like" CG42355 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037486 CG14605 - http://flybase.org/reports/FBgn0037486 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "BcDNA:AT16877, CG14605" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG14605 11-Aug-17 DroID_v2017_08 "Drer\LOC101882338, Drer\slc2a10, Drer\slc2a12, Drer\slc2a8, Drer\slc2a6, Drer\slc2a13b" "Scer\HXT13, Scer\HXT4, Scer\HXT6, Scer\YDR387C, Scer\HXT15, Scer\HXT17, Scer\HXT11, Scer\ITR1, Scer\VBA1, Scer\HXT14, Scer\HXT8, Scer\HXT7, Scer\VBA4, Scer\MPH2, Scer\YMR279C, Scer\HXT2, Scer\MAL11, Scer\HXT9, Scer\GAL2, Scer\GEX1, Scer\STL1, Scer\VBA5, Scer\ITR2, Scer\VBA2, Scer\ATR1, Scer\ENB1, Scer\MAL31, Scer\SNF3, Scer\HXT10, Scer\VBA3, Scer\HXT1, Scer\HXT3, Scer\GEX2, Scer\MPH3, Scer\HXT5, Scer\AZR1, Scer\RGT2, Scer\YFL040W, Scer\YDL199C, Scer\HXT16, Scer\SGE1" - "Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a12" "Mmus\Slc2a10, Mmus\Slc2a8, Mmus\Slc2a13, Mmus\Slc2a6, Mmus\Slc2a12" "Hsap\SLC2A6, Hsap\SLC2A12, Hsap\SLC2A8, Hsap\SLC2A10, Hsap\SLC2A13" viable FBgn0001472 l(1)9Ea lethal (1) 9Ea http://flybase.org/reports/FBgn0001472 - gene - - - "EM31, l(1)EM32, l(1)EM22, l(1)9Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069114 mus216 mutagen-sensitive 216 http://flybase.org/reports/FBgn0069114 gene - - - mus216 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0003463 sog short gastrulation http://flybase.org/reports/FBgn0003463 "FBgn0027206, FBgn0028353, FBgn0029046" protein_coding_gene collagen binding ; GO:0005518 | inferred from direct assay "positive regulation of transforming growth factor beta receptor signaling pathway ; GO:0030511 | traceable author statement torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor amnioserosa formation ; GO:0007378 | traceable author statement maternal specification of dorsal/ventral axis, oocyte, soma encoded ; GO:0007313 | inferred from mutant phenotype ring gland development ; GO:0035271 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from genetic interaction with tor posterior Malpighian tubule development ; GO:0061328 | inferred from mutant phenotype negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | traceable author statement ectoderm development ; GO:0007398 | traceable author statement BMP signaling pathway ; GO:0030509 | non-traceable author statement regulation of BMP signaling pathway ; GO:0030510 | traceable author statement ectoderm development ; GO:0007398 | non-traceable author statement zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | non-traceable author statement" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "Sog, CG9224, l(1)G0160, l(1)G0395, l(1)G0479, sog, SOG, Dm sog" "IPR001007:VWFC domain, IPR010895:CHRD, IPR016353:Chordin" CG9224 11-Aug-17 DroID_v2017_08 "Drer\chrdl2, Drer\zgc:113531, Drer\si:dkey-283b1.7, Drer\chd, Drer\vwc2l, Drer\vwc2" - Cele\crm-1 "Xtro\chrd, Xtro\chrdl1" "Mmus\Chrdl2, Mmus\Vwc2l, Mmus\Chrd, Mmus\Vwc2, Mmus\Chrdl1, Mmus\Vwde" "Hsap\CHRDL2, Hsap\CHRD, Hsap\CHRDL1, Hsap\VWC2, Hsap\VWC2L" " larval stage , embryonic stage | stage 5 , pupal stage | 18-20 hr , embryonic stage | stage 10 , embryonic stage | cycle 13,14 , embryonic stage | stage 8 , embryonic stage | stage 12 , pupal stage | 25-30 hr " " dorsal mesothoracic disc | restricted

, ventral thoracic disc | restricted

, ventral neurogenic region

, wing cell | subset

, organism | lateral & striped

,

lateral , ventral midline

, endoderm | restricted

, wing cell

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,dominant,partially lethal - majority die,lethal,maternal effect,somatic clone,heat sensitive,wild-type,neuroanatomy defective,viable" "embryo,posterior crossvein,wing vein L3,wing vein L4,wing vein L5,wing vein,wing vein L2,ectopic,embryonic/first instar larval cuticle,denticle belt,maternal effect,somatic clone,embryonic epidermis,dorsal appendage,egg operculum,amnioserosa,chorion,heat sensitive,presumptive embryonic/larval peripheral nervous system,dorsal abdominal cluster,lateral abdominal cluster,dorsal closure embryo,embryonic/larval dorsal trunk,embryonic/larval visceral branch,embryonic/larval dorsal branch,mandibular segment,cuticle,extended germ band embryo,ventral neurectoderm,adult salivary gland primordium,filzkorper,embryonic head,denticle,embryonic Malpighian tubule,corpus cardiacum primordium,wing,anterior crossvein,distal,anterior,crossvein,supernumerary,scutellar bristle,eye,antenna,wing cell" DRSC20379 K -0.244815193 0.078516105 1.317291769 0.239538143 2.099123951 1.67880489 FBgn0030539 CG1368 - http://flybase.org/reports/FBgn0030539 protein_coding_gene - - - CG1368 IPR004019:YLP motif CG1368 11-Aug-17 DroID_v2017_08 Drer\pou2af1 - - - Mmus\Pou2af1 Hsap\POU2AF1 FBgn0001582 l(1)C lethal (1) C http://flybase.org/reports/FBgn0001582 - gene - - - l(1)C - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265542 CR44392 - http://flybase.org/reports/FBgn0265542 non_protein_coding_gene - - - CR44392 - CR44392 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264866 CR44057 - http://flybase.org/reports/FBgn0264866 non_protein_coding_gene - - - "CR44057, lincRNA.30" - CR44057 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065861 l(2)SH0273 lethal (2) SH0273 http://flybase.org/reports/FBgn0065861 gene - - - "l(2)SH0273, l(2)SH2 0273" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037608 mRpL19 mitochondrial ribosomal protein L19 http://flybase.org/reports/FBgn0037608 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P49406 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P49406 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:P49406 "L19, CG8039, mRpL19, mRPL19" "IPR001857:Ribosomal protein L19, IPR008991:Translation protein SH3-like domain" CG8039 11-Aug-17 DroID_v2017_08 Drer\mrpl19 Scer\IMG1 Cele\mrpl-19 Xtro\mrpl19 Mmus\Mrpl19 Hsap\MRPL19 "viable,visible,lethal,recessive" trichogen cell FBgn0032649 CG15145 - http://flybase.org/reports/FBgn0032649 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15145 "IPR032840:MAATS1 domain, IPR026720:Protein MAATS1" CG15145 11-Aug-17 DroID_v2017_08 Drer\maats1 - - Xtro\maats1 Mmus\Maats1 Hsap\MAATS1 viable FBgn0040355 CG3526 - http://flybase.org/reports/FBgn0040355 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 - - "EG:BACR43E12.4, CG3526" "IPR000433:Zinc finger, ZZ-type, IPR013087:Zinc finger C2H2-type, IPR008598:Drought induced 19 protein type, zinc-binding domain" CG3526 11-Aug-17 DroID_v2017_08 Drer\kcmf1 - Cele\ZK652.6 "Xtro\kcmf1, Xtro\rnf138" "Mmus\Kcmf1, Mmus\Rnf125, Mmus\Rnf166, Mmus\Rnf138" "Hsap\RNF138, Hsap\RNF125, Hsap\KCMF1, Hsap\RNF166" "partially lethal - majority die,some die during pupal stage" FBgn0085107 2.15.43a 2.15.43a http://flybase.org/reports/FBgn0085107 gene - - - 2.15.43a - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0040168 l(1)G0366 lethal (1) G0366 http://flybase.org/reports/FBgn0040168 gene - - - l(1)G0366 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0000622 e(y)6 enhancer of yellow 6 http://flybase.org/reports/FBgn0000622 - gene - - - e(y)6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,visible" "macrochaeta,wing,adult cuticle" FBgn0060435 l(3)S125104b lethal (3) S125104b http://flybase.org/reports/FBgn0060435 gene - - - "1251/04, l(3)S125104b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002110 l(2)1323 lethal (2) 1323 http://flybase.org/reports/FBgn0002110 - gene - - - l(2)1323 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000129 Ars-region7 Autonomous replicating sequence region 7 http://flybase.org/reports/FBgn0000129 - region - - - "ars410, Ars-region7, Ars7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058189 CG40189 - http://flybase.org/reports/FBgn0058189 protein_coding_gene - - - CG40189 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262101 CG42854 - http://flybase.org/reports/FBgn0262101 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42854 IPR032071:Domain of unknown function DUF4806 CG42854 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067900 IM22 Immune induced molecule 22 http://flybase.org/reports/FBgn0067900 gene - defense response ; GO:0006952 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "DIM 22, IM22" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067750 l(1)G0195 lethal (1) G0195 http://flybase.org/reports/FBgn0067750 gene - - - l(1)G0195 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0043042 l(2)42Aa lethal (2) 42Aa http://flybase.org/reports/FBgn0043042 gene - - - l(2)42Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067401 Rst(2)DDT-WIS1lab Resistant to DDT on II Wisconsin 1 lab http://flybase.org/reports/FBgn0067401 gene - response to DDT ; GO:0046680 | inferred from mutant phenotype response to insecticide ; GO:0017085 | inferred from mutant phenotype - Rst(2)DDT-WIS1lab - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0039784 CG9698 - http://flybase.org/reports/FBgn0039784 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG9698-E, CG9698" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG9698 11-Aug-17 DroID_v2017_08 "Drer\zgc:158254, Drer\p4htm, Drer\p4ha3, Drer\p4ha1a, Drer\p4ha1b, Drer\zgc:152670, Drer\p4ha2" - "Cele\C14E2.4, Cele\phy-2, Cele\phy-3, Cele\dpy-18, Cele\Y43F8B.19, Cele\phy-4" "Xtro\p4ha2, Xtro\p4ha1, Xtro\p4ha3" "Mmus\P4ha2, Mmus\P4ha3, Mmus\P4htm, Mmus\P4ha1" "Hsap\P4HTM, Hsap\P4HA3, Hsap\P4HA2, Hsap\P4HA1" "viable,fertile" FBgn0013708 mt:tRNA:Val-TAC mitochondrial transfer RNA:Valine-TAC http://flybase.org/reports/FBgn0013708 FBgn0002867 tRNA_gene - - - "CR34095, tRNA-Val, mtdbD00006313, mt:tRNA:Val-TAC, mt:tRNA:V, tRNA[Val], mt:tRNA[Val]" - CR34095 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261858 CG42787 - http://flybase.org/reports/FBgn0261858 protein_coding_gene gamma-tubulin binding ; GO:0043015 | inferred from biological aspect of ancestor with PANTHER:PTN002003414 interphase microtubule nucleation by interphase microtubule organizing center ; GO:0051415 | inferred from biological aspect of ancestor with PANTHER:PTN002003414 gamma-tubulin complex localization ; GO:0033566 | inferred from biological aspect of ancestor with PANTHER:PTN002003414 mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN002003414 gamma-tubulin ring complex ; GO:0008274 | inferred from biological aspect of ancestor with PANTHER:PTN002003414 interphase microtubule organizing center ; GO:0031021 | inferred from biological aspect of ancestor with PANTHER:PTN002003414 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN002003414 equatorial microtubule organizing center ; GO:0000923 | inferred from biological aspect of ancestor with PANTHER:PTN002003414 "CG42787, Mzt1" IPR022214:Mitotic-spindle organizing protein 1 CG42787 11-Aug-17 DroID_v2017_08 Drer\si:dkey-15d12.2 - - Xtro\mzt1 Mmus\Mzt1 Hsap\MZT1 FBgn0000122 Ars Arylsulfatase http://flybase.org/reports/FBgn0000122 - gene arylsulfatase activity ; GO:0004065 | inferred from direct assay - - "ARS, Ars" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003290 Rst(3)FU Resistant to fluorouracil http://flybase.org/reports/FBgn0003290 - gene - - - Rst(3)FU - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0005338 pxl proximalless http://flybase.org/reports/FBgn0005338 - gene - - - pxl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile,female sterile" photoreceptor FBgn0259587 GG01326 - http://flybase.org/reports/FBgn0259587 gene - - - GG01326 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing cell,tarsal segment,unguis" FBgn0001544 l(1)15Aa lethal (1) 15Aa http://flybase.org/reports/FBgn0001544 - gene - - - "l(1)i15b, i15b, l7, l(1)l7, l(1)15Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039883 RhoGAP100F Rho GTPase activating protein at 100F http://flybase.org/reports/FBgn0039883 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with UniProtKB:Q86NH1 GTPase activator activity ; GO:0005096 | inferred from sequence model "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 activation of GTPase activity ; GO:0090630 | inferred from sequence or structural similarity with UniProtKB:Q86NH1 R7 cell development ; GO:0045467 | inferred from mutant phenotype maintenance of presynaptic active zone structure ; GO:0048790 | inferred from mutant phenotype Rho protein signal transduction ; GO:0007266 | inferred from sequence model cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype axon extension involved in axon guidance ; GO:0048846 | inferred from mutant phenotype synaptic vesicle localization ; GO:0097479 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from biological aspect of ancestor with PANTHER:PTN000571279" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000571279 presynaptic active zone ; GO:0048786 | inferred from direct assay presynaptic active zone ; GO:0048786 | "DSyd-1, CG1976, 1976, RhoGAP100F, Syd-1, Syd1, DSyd1, syd-1, dsyd-1, RHOGAP100F" "IPR000008:C2 domain, IPR000198:Rho GTPase-activating protein domain, IPR001478:PDZ domain, IPR008936:Rho GTPase activation protein" CG1976 11-Aug-17 DroID_v2017_08 "Drer\syde1, Drer\syde2" "Scer\BEM2, Scer\RGD1, Scer\RGA1, Scer\ECM25, Scer\BEM3, Scer\RGA2" Cele\syd-1 Xtro\syde2 "Mmus\Syde1, Mmus\Syde2" "Hsap\SYDE1, Hsap\SYDE2" "neuroanatomy defective,somatic clone" "photoreceptor cell R7,somatic clone" DRSC28096 K 0.043073573 -0.253606431 0.351996241 0.430394115 0.325407229 2.437494716 FBgn0263211 CR43381 - http://flybase.org/reports/FBgn0263211 pseudogene_attribute - - - CR43381 - CR43381 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003752 translucent translucent http://flybase.org/reports/FBgn0003752 - gene - - - "trl, translucent" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" pigment cell FBgn0060366 l(3)S138112 lethal (3) S138112 http://flybase.org/reports/FBgn0060366 gene - - - "1381/12, l(3)S138112" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065979 iab-6-2.s iab-6-2.s http://flybase.org/reports/FBgn0065979 gene - - - "6-2.s, iab-6-2.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001745 l(1)HM17 lethal (1) HM17 http://flybase.org/reports/FBgn0001745 - gene - - - l(1)HM17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0069227 gl(2L)386-2 gl(2L)386-2 http://flybase.org/reports/FBgn0069227 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)386-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0065574 l(2)SH0955 lethal (2) SH0955 http://flybase.org/reports/FBgn0065574 gene - - - "l(2)SH0955, l(2)SH2 0955" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030735 CG3632 - http://flybase.org/reports/FBgn0030735 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with HGNC:7451 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with HGNC:7451 protein dephosphorylation ; GO:0006470 | non-traceable author statement peptidyl-tyrosine dephosphorylation ; GO:0035335 | inferred from sequence or structural similarity with HGNC:7451 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:7451 CG3632 "IPR000306:FYVE zinc finger, IPR000387:Tyrosine specific protein phosphatases domain, IPR010569:Myotubularin-like phosphatase domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR016130:Protein-tyrosine phosphatase, active site, IPR017455:Zinc finger, FYVE-related, IPR011993:PH domain-like, IPR030564:Myotubularin family, IPR029021:Protein-tyrosine phosphatase-like, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR003595:Protein-tyrosine phosphatase, catalytic" CG3632 11-Aug-17 DroID_v2017_08 "Drer\mtm1, Drer\mtmr4, Drer\mtmr3, Drer\LOC100333801, Drer\sbf2" Scer\YMR1 Cele\mtm-3 "Xtro\mtmr4, Xtro\mtmr3, Xtro\sbf2" "Mmus\Mtmr4, Mmus\Mtmr3, Mmus\Sbf2" "Hsap\MTMR4, Hsap\SBF2, Hsap\MTMR3" "visible,viable,fertile" "wing vein,ectopic,trichogen cell" FBgn0036837 CG18135 - http://flybase.org/reports/FBgn0036837 protein_coding_gene starch binding ; GO:2001070 | inferred from electronic annotation with InterPro:IPR002044 glycerophosphodiester phosphodiesterase activity ; GO:0008889 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 glycerophosphocholine phosphodiesterase activity ; GO:0047389 | inferred from biological aspect of ancestor with PANTHER:PTN001120996 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cellular phosphate ion homeostasis ; GO:0030643 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 glycerophospholipid catabolic process ; GO:0046475 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 extracellular space ; GO:0005615 | inferred from direct assay CG18135 "IPR030395:Glycerophosphodiester phosphodiesterase domain, IPR000909:Phosphatidylinositol-specific phospholipase C, X domain, IPR002044:Carbohydrate binding module family 20, IPR013784:Carbohydrate-binding-like fold, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR033506:Glycerophosphodiester phosphodiesterase Gde1, IPR013783:Immunoglobulin-like fold" CG18135 11-Aug-17 DroID_v2017_08 Drer\gpcpd1 "Scer\GDE1, Scer\PHO81" "Cele\gpcp-2, Cele\gpcp-1" - Mmus\Gpcpd1 Hsap\GPCPD1 "viable,fertile" FBgn0058113 CG40113 - http://flybase.org/reports/FBgn0058113 protein_coding_gene - - - CG40113 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053072 CG33072 - http://flybase.org/reports/FBgn0053072 protein_coding_gene - - - CG33072 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028256 l(3)76BDg lethal (3) 76BDg http://flybase.org/reports/FBgn0028256 gene - spermatid differentiation ; GO:0048515 | inferred from mutant phenotype - l(3)76BDg - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,lethal,recessive" FBgn0268008 T:GPI-dally GPI domain of dally http://flybase.org/reports/FBgn0268008 engineered_tag - - - T:GPI-dally - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001354 l(1)1EFc lethal (1) 1EFc http://flybase.org/reports/FBgn0001354 - gene - - - "l(1)BA3, l(1)1EFc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035437 Strip Striatin interacting protein http://flybase.org/reports/FBgn0035437 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of hippo signaling ; GO:0035331 | inferred from genetic interaction with hpo axon extension ; GO:0048675 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype endosome organization ; GO:0007032 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D presynapse ; GO:0098793 | inferred from direct assay "CG11526, Strip, strip" "IPR012486:N1221-like, IPR011989:Armadillo-like helical, IPR021819:Protein of unknown function DUF3402" CG11526 11-Aug-17 DroID_v2017_08 "Drer\strip2, Drer\strip1" Scer\FAR11 Cele\farl-11 Xtro\strip1 "Mmus\Strip2, Mmus\Strip1" "Hsap\STRIP2, Hsap\STRIP1" "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" FBgn0082679 E(ftz)4236 E(ftz)4236 http://flybase.org/reports/FBgn0082679 gene - - - "4236, E(ftz)4236" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050464 Ir52d Ionotropic receptor 52d http://flybase.org/reports/FBgn0050464 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir52d, CG12961, DmelIR52d, CG30464, IR52d" - CG30464 11-Aug-17 DroID_v2017_08 - - "Cele\glr-3, Cele\glr-7" - - - viable FBgn0035998 CG3437 - http://flybase.org/reports/FBgn0035998 protein_coding_gene - - - CG3437 IPR005062:SAC3/GANP/THP3 CG3437 11-Aug-17 DroID_v2017_08 "Drer\mcm3ap, Drer\si:zfos-452g4.1" Scer\SAC3 "Cele\tag-115, Cele\F20D12.2" Xtro\mcm3ap "Mmus\Sac3d1, Mmus\Mcm3ap" "Hsap\SAC3D1, Hsap\MCM3AP" viable FBgn0004694 Su(var)2-2 Suppressor of variegation 2-2 http://flybase.org/reports/FBgn0004694 - gene - - - "Su-var(2)2, Su(var)2-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0030218 CG1628 - http://flybase.org/reports/FBgn0030218 protein_coding_gene L-ornithine transmembrane transporter activity ; GO:0000064 | inferred from biological aspect of ancestor with PANTHER:PTN000641358 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 L-ornithine transmembrane transporter activity ; GO:0000064 | inferred from sequence or structural similarity with UniProtKB:Q9Y619 mitochondrial ornithine transport ; GO:0000066 | inferred from biological aspect of ancestor with PANTHER:PTN000641358 mitochondrial ornithine transport ; GO:0000066 | inferred from sequence or structural similarity with UniProtKB:Q9Y619 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000641358 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q9Y619 CG1628 "IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG1628 11-Aug-17 DroID_v2017_08 "Drer\slc25a45, Drer\slc25a47a, Drer\si:dkey-150i13.2, Drer\slc25a48, Drer\slc25a20, Drer\slc25a15a, Drer\slc25a15b" Scer\ORT1 "Cele\R07B7.10, Cele\T10F2.2" "Xtro\slc25a48, Xtro\slc25a47, Xtro\slc25a15, Xtro\MGC108450, Xtro\slc25a20.2, Xtro\slc25a29, Xtro\slc25a20, Xtro\slc25a45" "Mmus\Slc25a20, Mmus\Slc25a45, Mmus\Slc25a2, Mmus\Slc25a15, Mmus\Slc25a48, Mmus\Slc25a47, Mmus\Slc25a29" "Hsap\SLC25A48, Hsap\SLC25A47, Hsap\SLC25A45, Hsap\SLC25A2, Hsap\SLC25A29, Hsap\SLC25A20, Hsap\SLC25A15" "partially lethal - majority die,some die during pupal stage" FBgn0005123 l(1)nib lethal no imaginal buds http://flybase.org/reports/FBgn0005123 - gene - - - l(1)nib - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "melanotic mass,embryonic/larval digestive system,imaginal disc primordium" FBgn0021850 l(2)k14603b lethal (2) k14603b http://flybase.org/reports/FBgn0021850 - gene - - - l(2)k14603b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014022 Rlb1 Rlb1 http://flybase.org/reports/FBgn0014022 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN001154492 membrane ; GO:0016020 | inferred from direct assay 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN001154492 nucleus ; GO:0005634 | inferred from direct assay "CG8161, Rlb1, Rlb, Ov30" - CG8161 11-Aug-17 DroID_v2017_08 Drer\srfbp1 Scer\BUD22 Cele\F18C12.3 Xtro\srfbp1 Mmus\Srfbp1 Hsap\SRFBP1 viable FBgn0062598 Mod(var)1485 Mod(var)1485 http://flybase.org/reports/FBgn0062598 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1485, Mod(var)1485" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0263411 CR43457 - http://flybase.org/reports/FBgn0263411 non_protein_coding_gene - - - "CR43457, lincRNA.847" - CR43457 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036382 CG13737 - http://flybase.org/reports/FBgn0036382 protein_coding_gene - - - CG13737 - CG13737 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023540 CG3630 - http://flybase.org/reports/FBgn0023540 - protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity with MGI:MGI:2444891 positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with MGI:MGI:2444891 actin cytoskeleton ; GO:0015629 | inferred from sequence or structural similarity with MGI:MGI:2444891 "EG:152A3.3, 152A3.3, CG3630" "IPR026111:Actin-binding Rho-activating protein, IPR027817:Costars domain" CG3630 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-29b11.3, Drer\abrab, Drer\abracl, Drer\abraa" - "Cele\tag-243, Cele\F36F2.1" Xtro\abra "Mmus\Abra, Mmus\Abracl" "Hsap\ABRA, Hsap\ABRACL" "viable,fertile" DRSC28903 K 0.295156162 0.036560969 0.727557886 0.04233369 0.558635196 2.510713194 FBgn0086355 Tpi Triose phosphate isomerase http://flybase.org/reports/FBgn0086355 protein_coding_gene triose-phosphate isomerase activity ; GO:0004807 | inferred from mutant phenotype triose-phosphate isomerase activity ; GO:0004807 | inferred from direct assay triose-phosphate isomerase activity ; GO:0004807 | inferred from sequence or structural similarity with UniProtKB:P17751 glyceraldehyde-3-phosphate biosynthetic process ; GO:0046166 | inferred from biological aspect of ancestor with PANTHER:PTN000474559 myoblast fusion ; GO:0007520 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype glycolytic process ; GO:0006096 | inferred from mutant phenotype gluconeogenesis ; GO:0006094 | inferred from biological aspect of ancestor with PANTHER:PTN000474559 neurological system process ; GO:0050877 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype glyceraldehyde-3-phosphate metabolic process ; GO:0019682 | inferred from sequence or structural similarity with UniProtKB:P17751 response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype glycerol catabolic process ; GO:0019563 | inferred from biological aspect of ancestor with PANTHER:PTN000474559 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000474559 Z disc ; GO:0030018 | inferred from direct assay M band ; GO:0031430 | inferred from direct assay "TPI, Tpi, sgk, tpi, ND14, TPIS, CG2171, wstd" "IPR000652:Triosephosphate isomerase, IPR013785:Aldolase-type TIM barrel, IPR020861:Triosephosphate isomerase, active site, IPR022896:Triosephosphate isomerase, bacterial/eukaryotic" CG2171 11-Aug-17 DroID_v2017_08 "Drer\tpi1a, Drer\tpi1b" Scer\TPI1 Cele\tpi-1 Xtro\tpi1 Mmus\Tpi1 Hsap\TPI1 embryonic stage -- adult stage larval stage | third instar dorsal mesothoracic disc

FBgn0028589 l(3)L7160a lethal (3) L7160a http://flybase.org/reports/FBgn0028589 gene - - - "l(3)L7160, l(3)L7160a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035109 CG13876 - http://flybase.org/reports/FBgn0035109 protein_coding_gene - - - CG13876 IPR026698:Uncharacterised protein C3orf38 (DUF4518) CG13876 11-Aug-17 DroID_v2017_08 Drer\si:ch211-261p9.4 - - Xtro\c3orf38 Mmus\4930453N24Rik Hsap\C3orf38 viable FBgn0262993 CR43301 - http://flybase.org/reports/FBgn0262993 non_protein_coding_gene - - - CR43301 - CR43301 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261601 M(1)5D6A Minute (1) 5D6A http://flybase.org/reports/FBgn0261601 gene - - - M(1)5D6A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060712 l(3)S070116 lethal (3) S070116 http://flybase.org/reports/FBgn0060712 gene - - - "0701/16, l(3)S070116" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0058404 CG40404 - http://flybase.org/reports/FBgn0058404 protein_coding_gene - - - CG40404 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020513 ade5 ade5 http://flybase.org/reports/FBgn0020513 - protein_coding_gene phosphoribosylaminoimidazolesuccinocarboxamide synthase activity ; GO:0004639 | inferred from sequence or structural similarity with UniProtKB:P0A7D7 inferred from genetic interaction with UniProtKB:P0A7D7 phosphoribosylaminoimidazole carboxylase activity ; GO:0004638 | inferred from sequence or structural similarity with SGD:S000005654 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype 'de novo' IMP biosynthetic process ; GO:0006189 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005654 "AIRc-SAICARs, Ade5, CG3989, ade5" "IPR000031:PurE domain, IPR018236:SAICAR synthetase, conserved site, IPR028923:SAICAR synthetase/ADE2, N-terminal, IPR033626:Class II PurE" CG3989 11-Aug-17 DroID_v2017_08 Drer\paics "Scer\ADE2, Scer\ADE1" Cele\pacs-1 Xtro\paics.1 Mmus\Paics Hsap\PAICS "behavior defective,recessive,eye color defective,auxotroph,lethal,viable" pigment cell FBgn0085746 CR40571 - http://flybase.org/reports/FBgn0085746 rRNA_gene - - - CR40571 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002400 l(3)99Da lethal (3) 99Da http://flybase.org/reports/FBgn0002400 - gene - - - l(3)99Da - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015513 mbc myoblast city http://flybase.org/reports/FBgn0015513 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with rols Rac guanyl-nucleotide exchange factor activity ; GO:0030676 | inferred from genetic interaction with Rac1 "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR026791 myoblast fusion ; GO:0007520 | traceable author statement dorsal closure ; GO:0007391 | traceable author statement myoblast fusion ; GO:0007520 | inferred from mutant phenotype larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype activation of GTPase activity ; GO:0090630 | inferred from genetic interaction with Rac1 anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | traceable author statement muscle attachment ; GO:0016203 | inferred from genetic interaction with msk inferred from genetic interaction with Ced-12 activation of GTPase activity ; GO:0090630 | inferred from genetic interaction with Rac1, Rac2, Ced-12 inferred from genetic interaction with Rac1, Ced-12 cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype" extrinsic component of plasma membrane ; GO:0019897 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay ruffle ; GO:0001726 | traceable author statement "Mbc, MBC, Su(rac)1, CG10379, mbc, MBC/DOCK180, Dm MBC, Dock180, DOCK180, dock180" "IPR001452:SH3 domain, IPR027357:DHR-2 domain, IPR000008:C2 domain, IPR011989:Armadillo-like helical, IPR026791:Dedicator of cytokinesis, IPR027007:DHR-1 domain, IPR010703:Dedicator of cytokinesis, C-terminal, IPR032376:Dedicator of cytokinesis, N-terminal domain" CG10379 11-Aug-17 DroID_v2017_08 "Drer\dock5, Drer\dock1, Drer\si:dkey-81e3.1, Drer\dock3, Drer\dock4b" Scer\DCK1 Cele\ced-5 "Xtro\dock1, Xtro\dock3, Xtro\dock2, Xtro\dock4" "Mmus\Dock1, Mmus\Dock5, Mmus\Dock2, Mmus\Dock3, Mmus\Dock4" "Hsap\DOCK2, Hsap\DOCK5, Hsap\DOCK3, Hsap\DOCK1, Hsap\DOCK4" " embryonic stage | stage >=12 , embryonic stage | stage 12-14 , adult stage | male , adult stage | female , embryonic stage | stage 16 , pupal stage , embryonic stage | stage 12 , embryonic stage | stage 14 , embryonic stage | 0-4 hr , embryonic stage | stage 5 , embryonic stage | stage 7-12 , embryonic stage , embryonic stage | stage 4 " " visceral mesoderm

, somatic mesoderm

, embryonic/larval dorsal vessel

, endoderm

, embryonic/larval visceral muscle

, ectoderm | striped

,

lateral , ectoderm

, pole cell

" " embryonic stage | stage 12 , embryonic stage | stage 16 , embryonic stage | stage 5 , embryonic stage | stage 14 " " endoderm

, myoblast

, embryonic/larval dorsal vessel

, pole cell

, embryonic/larval visceral muscle

, ectoderm

" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval somatic muscle,embryonic Malpighian tubule,embryonic myoblast,embryonic dorsal epidermis,axon & ventral nerve cord,longitudinal connective,commissure,border follicle cell,somatic clone,presumptive embryonic/larval muscle system,A1-7 dorsal acute muscle 1,germline clone,lateral longitudinal fascicle,muscle founder cell,longitudinal muscle,embryonic/larval muscle system,circular visceral muscle fiber,myoblast,midgut constriction,embryonic visceral muscle,circular visceral muscle primordium,fusion competent cell,embryonic/larval Malpighian tubule,embryonic/larval anterior Malpighian tubule,Malpighian tubule Type II cell,thorax,chaeta,supernumerary,mesothoracic tergum,reticular neuropil associated glial cell,gamma Kenyon cell" FBgn0263388 CR43440 - http://flybase.org/reports/FBgn0263388 non_protein_coding_gene - - - "CG43440, CR43440" - CR43440 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065119 l(3)SH150 lethal (3) SH150 http://flybase.org/reports/FBgn0065119 gene - - - "l(3)SH150, l(2)SH3 150" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266730 CR45203 - http://flybase.org/reports/FBgn0266730 non_protein_coding_gene - - - CR45203 - CR45203 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060322 l(3)S146901 lethal (3) S146901 http://flybase.org/reports/FBgn0060322 gene - - - "1469/01, l(3)S146901" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0020892 Su(osk)K6 Suppressor of oskar K6 http://flybase.org/reports/FBgn0020892 - gene - - - "K6, Su(osk)K6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003283 rsi reduced size http://flybase.org/reports/FBgn0003283 - gene - - - rsi - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,fertile,viable,reduced" FBgn0267270 CR45706 - http://flybase.org/reports/FBgn0267270 non_protein_coding_gene - - - CR45706 - CR45706 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029642 CG3592 - http://flybase.org/reports/FBgn0029642 protein_coding_gene - - - "frag7, CG3592" IPR006593:Cytochrome b561/ferric reductase transmembrane CG3592 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043597 E(ro[DOM])1065 E(ro[DOM])1065 http://flybase.org/reports/FBgn0043597 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available E(ro[DOM])1065 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0003654 sw short wing http://flybase.org/reports/FBgn0003654 "FBgn0013761, FBgn0031096" protein_coding_gene dynein light chain binding ; GO:0045503 | inferred from physical interaction with ctp inferred from physical interaction with Dlc90F dynein heavy chain binding ; GO:0045504 | inferred from sequence or structural similarity with UniProtKB:P54703 dynactin binding ; GO:0034452 | inferred from physical interaction with DCTN1-p150 centrosome localization ; GO:0051642 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from genetic interaction with dop eye photoreceptor cell differentiation ; GO:0001754 | inferred from genetic interaction with DCTN1-p150 microtubule-based movement ; GO:0007018 | inferred from direct assay protein localization to kinetochore ; GO:0034501 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasmic dynein complex ; GO:0005868 | inferred from direct assay "DIC, Cdic, dic, 17-234, Dic19C, IC74, IC, CG18000, Dic19B, Dic, cDIC, l(1)19Bb, sw, Cdic2b" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2" CG18000 11-Aug-17 DroID_v2017_08 "Drer\LOC103908626, Drer\dync1i2b, Drer\dnai2a, Drer\dnai1.1, Drer\dync1i1" "Scer\PAC11, Scer\PFS2" "Cele\prp-17, Cele\dyci-1" "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Wdr63, Mmus\Dync1i1, Mmus\Dync1i2" "Hsap\WDR60, Hsap\DYNC1I2, Hsap\DYNC1I1" embryonic stage && adult stage "female sterile,neuroanatomy defective,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,wild-type,lethal,visible,paralytic,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,viable,fertile,reduced,partially lethal - majority die" "wing vein,dendritic arborizing neuron,wing,eye,wing margin,ommatidium,cystic bulge,nucleus & spermatid,mesothoracic tergum" FBgn0267566 CR45906 - http://flybase.org/reports/FBgn0267566 non_protein_coding_gene - - - CR45906 - CR45906 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037731 CG18542 - http://flybase.org/reports/FBgn0037731 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18542 IPR016181:Acyl-CoA N-acyltransferase CG18542 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005162 l(2)G305 lethal (2) G305 http://flybase.org/reports/FBgn0005162 - gene - - - l(2)G305 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025003 E(var)56-9 E(var)56-9 http://flybase.org/reports/FBgn0025003 - gene - - - "E-56/9, E(var)56-9" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021780 l(3)95Ba lethal (3) 95Ba http://flybase.org/reports/FBgn0021780 - gene - - - l(3)95Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003538 Stp-2 Strapped on 2 http://flybase.org/reports/FBgn0003538 - gene - - - Stp-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing margin,male" FBgn0005220 l(3)ET15 lethal Elaine Tasaka 15 http://flybase.org/reports/FBgn0005220 - gene - - - l(3)ET15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" FBgn0263594 lost lost http://flybase.org/reports/FBgn0263594 protein_coding_gene - "pole plasm mRNA localization ; GO:0019094 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from genetic interaction with rump pole cell development ; GO:0007277 | inferred from genetic interaction with rump mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype inferred from genetic interaction with rump" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "growl, lost, CG14648, nev, anon-WO0118547.126, Growl" "IPR002698:5-formyltetrahydrofolate cyclo-ligase, IPR034359:MTHFSD, RNA recognition motif" CG14648 11-Aug-17 DroID_v2017_08 Drer\mthfsd - - Xtro\mthfsd Mmus\Mthfsd Hsap\MTHFSD DRSC12002 E 0.27804616 -0.148413885 0.089605695 -1.514069813 0.207309794 1.298666913 FBgn0028106 l(3)S070103 lethal (3) S070103 http://flybase.org/reports/FBgn0028106 gene - - - "0701/03, l(3)S070103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060605 l(3)S091009b lethal (3) S091009b http://flybase.org/reports/FBgn0060605 gene - - - "0910/09, l(3)S091009b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015900 anon-P1609-II anon-P1609-II http://flybase.org/reports/FBgn0015900 - gene - - - anon-P1609-II - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020910 RpL3 Ribosomal protein L3 http://flybase.org/reports/FBgn0020910 FBgn0025328 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000597 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000597 centrosome organization ; GO:0051297 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000597 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "RpL3, CG4863, rpL3, anon-EST:GressD4, Rpl3, L3, chr3R:7047878..7048035" "IPR000597:Ribosomal protein L3, IPR009000:Translation protein, beta-barrel domain, IPR019926:Ribosomal protein L3, conserved site" CG4863 11-Aug-17 DroID_v2017_08 Drer\rpl3 Scer\RPL3 Cele\rpl-3 "Xtro\rpl3l, Xtro\rpl3" "Mmus\Rpl3, Mmus\Rpl3l" "Hsap\RPL3L, Hsap\RPL3" embryonic stage " embryonic/larval midgut

, embryonic/larval muscle system

,

ubiquitous , embryonic/larval hindgut

" "lethal,viable" DRSC16834 IEK -2.011441404 -1.203192499 0.25041104 -3.541307955 1.508482165 1.178366178 FBgn0015340 anon-38Aa anon-38Aa http://flybase.org/reports/FBgn0015340 - gene - - - anon-38Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265204 CR44264 - http://flybase.org/reports/FBgn0265204 non_protein_coding_gene - - - CR44264 - CR44264 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032690 CG10333 - http://flybase.org/reports/FBgn0032690 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000002651 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype RNA splicing, via transesterification reactions ; GO:0000375 | inferred from biological aspect of ancestor with PANTHER:PTN000619358 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002651 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218" U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000619358 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "DmRH19, cg10333, CG10333, DmPrp28" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG10333 11-Aug-17 DroID_v2017_08 Drer\ddx23 Scer\PRP28 Cele\ddx-23 Xtro\ddx23 Mmus\Ddx23 Hsap\DDX23 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0026304 anon-16Fe anon-16Fe http://flybase.org/reports/FBgn0026304 - gene - - - "HL-XIV, anon-16Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032471 CG5122 - http://flybase.org/reports/FBgn0032471 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR000542" - - CG5122 IPR000542:Acyltransferase ChoActase/COT/CPT CG5122 11-Aug-17 DroID_v2017_08 "Drer\zgc:154046, Drer\chata, Drer\crot, Drer\cpt1b, Drer\si:ch211-256m1.8, Drer\cpt1cb, Drer\cratb, Drer\crata, Drer\cpt1aa, Drer\cpt1ab, Drer\LOC101884918" Scer\CAT2 "Cele\W03F9.4, Cele\B0395.3, Cele\cha-1" "Xtro\crat.1, Xtro\cpt1b, Xtro\crat.2, Xtro\chat, Xtro\LOC100490391" "Mmus\Chat, Mmus\Cpt1c, Mmus\Crat, Mmus\Crot, Mmus\Cpt1a, Mmus\Cpt1b" "Hsap\CHAT, Hsap\CPT1C, Hsap\CRAT, Hsap\CROT, Hsap\CPT1B, Hsap\CPT1A" "viable,fertile" FBgn0266550 Snup::Hsap\SSPN - http://flybase.org/reports/FBgn0266550 engineered_fusion_gene - - - Snup::Hsap\SSPN - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001850 l(1)ts5697 lethal (1) ts5697 http://flybase.org/reports/FBgn0001850 - gene - - - l(1)ts5697 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0030200 RabX2 RabX2 http://flybase.org/reports/FBgn0030200 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 "CG2885, DmRabX2, RabX2" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2885 11-Aug-17 DroID_v2017_08 "Drer\rab1ba, Drer\rab1bb, Drer\rabl6b, Drer\rabl6a, Drer\rsg1, Drer\rab33ba, Drer\zgc:171927, Drer\si:dkey-16l2.16, Drer\rab43, Drer\rab19, Drer\rab35b, Drer\zgc:101559, Drer\rab1aa, Drer\rab1ab, Drer\rab33a, Drer\rab35a" "Scer\YPT1, Scer\TEM1" "Cele\rab-28, Cele\rab-35" "Xtro\rsg1, Xtro\rab33b, Xtro\rabl6, Xtro\rab28, Xtro\rab33a, Xtro\rab1a, Xtro\rab19" "Mmus\Rab28, Mmus\Rab33b, Mmus\Rab19, Mmus\Rsg1, Mmus\Rabl6, Mmus\Rab35, Mmus\Rab1a, Mmus\Rab33a, Mmus\Rab43, Mmus\Rab1b" "Hsap\RAB43, Hsap\RABL6, Hsap\RAB19, Hsap\RAB1B, Hsap\RAB35, Hsap\RAB1A, Hsap\RAB28, Hsap\RAB33A, Hsap\RSG1, Hsap\RAB33B" viable FBgn0264951 CR44120 - http://flybase.org/reports/FBgn0264951 non_protein_coding_gene - - - CR44120 - CR44120 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037822 CG14683 - http://flybase.org/reports/FBgn0037822 protein_coding_gene "molecular_function ; GO:0003674 | no biological data available methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR002903, InterPro:IPR023397" biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14683 "IPR002903:Ribosomal RNA small subunit methyltransferase H, IPR023397:S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG14683 11-Aug-17 DroID_v2017_08 Drer\mettl15 - - Xtro\mettl15 Mmus\Mettl15 Hsap\METTL15 FBgn0023161 Su(mg)1-7 Suppressor of modifier of gypsy 1-7 http://flybase.org/reports/FBgn0023161 - gene - - - Su(mg)1-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0043549 anon-12Ba anon-12Ba http://flybase.org/reports/FBgn0043549 gene - - - "cDNA F3, anon-12Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266503 s-276 - http://flybase.org/reports/FBgn0266503 gene - - - s-276 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022352 anon-25Db anon-25Db http://flybase.org/reports/FBgn0022352 - gene - - - "e3, anon-25Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031426 CG18641 - http://flybase.org/reports/FBgn0031426 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR033906 - "CG11535, CG18641" "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG18641 11-Aug-17 DroID_v2017_08 "Drer\lpl, Drer\LOC100331214, Drer\lipg, Drer\pla1a, Drer\lipib, Drer\lipca, Drer\lipia, Drer\LOC101884800" - - "Xtro\lpl, Xtro\lipg" "Mmus\Lipg, Mmus\Pnliprp2, Mmus\Pnlip, Mmus\Pnliprp1, Mmus\Pla1a, Mmus\Lpl, Mmus\Lipc, Mmus\Lipi, Mmus\Liph" "Hsap\LIPC, Hsap\PLA1A, Hsap\PNLIPRP3, Hsap\LIPG, Hsap\PNLIP, Hsap\PNLIPRP2, Hsap\PNLIPRP1, Hsap\LIPH, Hsap\LPL, Hsap\LIPI" viable FBgn0037293 CG12007 - http://flybase.org/reports/FBgn0037293 protein_coding_gene Rab geranylgeranyltransferase activity ; GO:0004663 | contributes_to inferred from direct assay protein geranylgeranylation ; GO:0018344 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype Rab-protein geranylgeranyltransferase complex ; GO:0005968 | inferred from direct assay "RabGGTalpha, PTAR3, CG12007" "IPR002088:Protein prenyltransferase, alpha subunit, IPR032955:Geranylgeranyl transferase type-2 subunit alpha" CG12007 11-Aug-17 DroID_v2017_08 Drer\rabggta Scer\BET4 Cele\M57.2 Xtro\rabggta Mmus\Rabggta "Hsap\PTAR1, Hsap\RABGGTA" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,tormogen cell" FBgn0065578 l(2)SH0949 lethal (2) SH0949 http://flybase.org/reports/FBgn0065578 gene - - - "l(2)SH0949, l(2)SH2 0949" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267818 CR46143 - http://flybase.org/reports/FBgn0267818 non_protein_coding_gene - - - CR46143 - CR46143 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032752 CG10702 - http://flybase.org/reports/FBgn0032752 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006211 transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from sequence or structural similarity with HGNC:6093 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from electronic annotation with InterPro:IPR006211 peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from sequence or structural similarity with HGNC:6093 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:6091 CG10702 "IPR000494:Receptor L-domain, IPR006211:Furin-like cysteine-rich domain, IPR006212:Furin-like repeat, IPR009030:Growth factor receptor cysteine-rich domain, IPR003961:Fibronectin type III, IPR032675:Leucine-rich repeat domain, L domain-like, IPR013783:Immunoglobulin-like fold" CG10702 11-Aug-17 DroID_v2017_08 "Drer\ros1, Drer\insrb, Drer\igf1rb, Drer\insra, Drer\igf1ra" - "Cele\rol-3, Cele\daf-2, Cele\let-23" "Xtro\igf1r, Xtro\insr, Xtro\insrr" "Mmus\Ros1, Mmus\Insrr, Mmus\Insr, Mmus\Igf1r" "Hsap\ERBB4, Hsap\ROS1, Hsap\INSRR, Hsap\IGF1R, Hsap\INSR" "viable,fertile" FBgn0265085 CR44196 - http://flybase.org/reports/FBgn0265085 non_protein_coding_gene - - - CR44196 - CR44196 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260801 EP2-430 - http://flybase.org/reports/FBgn0260801 gene - - - EP2-430 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263586 CR43611 - http://flybase.org/reports/FBgn0263586 non_protein_coding_gene - - - CR43611 - CR43611 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052692 CG32692 - http://flybase.org/reports/FBgn0052692 protein_coding_gene - - - CG32692 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050114 CG30114 - http://flybase.org/reports/FBgn0050114 protein_coding_gene - - - CG30114 - CG30114 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086219 zex zexless http://flybase.org/reports/FBgn0086219 gene - - - zex - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002412 l(3)a lethal (3) a http://flybase.org/reports/FBgn0002412 - gene - - - "l(3)1, l(3)a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000734 fs(1)288 female sterile (1) 288 http://flybase.org/reports/FBgn0000734 - gene - - - fs(1)288 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029089 cypress cypress http://flybase.org/reports/FBgn0029089 gene molecular_function ; GO:0003674 | no biological data available dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available cypress - - 11-Aug-17 DroID_v2017_08 - - - - - - dendrite | dorsal | embryonic stage FBgn0000744 fs(1)A248 female sterile (1) A248 http://flybase.org/reports/FBgn0000744 - gene - - - fs(1)A248 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,heat sensitive" female reproductive system FBgn0011164 l(1)DM-1 lethal (1) DM-1 http://flybase.org/reports/FBgn0011164 FBgn0010204 gene - - - l(1)DM-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058053 CR40053 - http://flybase.org/reports/FBgn0058053 non_protein_coding_gene - - - "BcDNA:AT11374, CG40053, CR40053" - CR40053 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261279 lqfR liquid facets-Related http://flybase.org/reports/FBgn0261279 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype inferred from genetic interaction with ds cell proliferation ; GO:0008283 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from direct assay "epsin-like, lqfR, CG42250, Epsin, epsin, CG31170, l(3)03685, LqfR, epsin02, CG13854, CG13853, CG31285, l(3)dsl-9, l(3)XII-10, l(3)dsl9, l(3)A9, XII-10, l(3)SG62, Tel2, epsinR, Lqfr, dTel2" "IPR016024:Armadillo-type fold, IPR008942:ENTH/VHS, IPR013809:ENTH domain, IPR019337:Telomere length regulation protein, conserved domain" CG42250 11-Aug-17 DroID_v2017_08 "Drer\epn2, Drer\epn3b, Drer\telo2, Drer\clint1b, Drer\epn3a, Drer\clint1a, Drer\epn1" "Scer\ENT1, Scer\ENT2, Scer\ENT5, Scer\TEL2, Scer\ENT4, Scer\ENT3" "Cele\epn-1, Cele\rsd-3, Cele\clk-2" "Xtro\epn2, Xtro\clint1, Xtro\telo2" "Mmus\Clint1, Mmus\Telo2, Mmus\Epn2, Mmus\Epn1" "Hsap\EPN2, Hsap\TELO2, Hsap\CLINT1, Hsap\EPN1" DRSC25247 K -0.257400008 -0.01794462 0.087617946 -0.654869014 0.120915882 2.464519502 FBgn0003097 PL(1)sp-S1 Polygenic locus sternopleural S1 http://flybase.org/reports/FBgn0003097 - gene - - - "PL(1)sp[S1], PL(1)sp-S1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086204 S(ls)6 - http://flybase.org/reports/FBgn0086204 gene - - - S(ls)6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016847 l(1)N27 lethal (1) N27 http://flybase.org/reports/FBgn0016847 - gene - - - "l(1)N27, N27" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086711 mol moladietz http://flybase.org/reports/FBgn0086711 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with numb protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR018469 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR018469 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR018469 plasma membrane ; GO:0005886 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay "CG4482, nip, BG:DS01219.1, l(2)35Bb, l35Bb, l(2)br3, l(2)br23, br3, B1, 35Bb, CG15268, l(2)SH1330, mol, l(2)SH2 1330, NIP, Mol" IPR018469:Dual oxidase maturation factor CG4482 11-Aug-17 DroID_v2017_08 Drer\duox2 - Cele\doxa-1 Xtro\duoxa1 "Mmus\Duoxa2, Mmus\Duoxa1" "Hsap\DUOXA1, Hsap\DUOXA2" DRSC01431 IE 1.666347799 -1.6121835 -1.638962866 0.121588718 0.685715965 0.759291439 FBgn0266796 CR45258 - http://flybase.org/reports/FBgn0266796 non_protein_coding_gene - - - CR45258 - CR45258 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065086 snmRNA:682 small non-messenger RNA 682 http://flybase.org/reports/FBgn0065086 non_protein_coding_gene - - - "Dm-682, snmRNA:682" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025692 Lfg Lifeguard http://flybase.org/reports/FBgn0025692 FBgn0033779 protein_coding_gene - - - "CK02213, BEST:CK02213, CG3814, Lfg, LFG" IPR006214:Bax inhibitor 1-related CG3814 11-Aug-17 DroID_v2017_08 "Drer\tmbim1, Drer\LOC566927, Drer\tmbim4, Drer\grinaa, Drer\faim2a, Drer\zgc:110410, Drer\faim2b, Drer\grinab, Drer\si:ch211-284o19.8" Scer\BXI1 "Cele\xbx-6, Cele\tmbi-4, Cele\tag-120, Cele\Y42H9AR.2" "Xtro\grina, Xtro\tmbim1, Xtro\tmbim4, Xtro\faim2" "Mmus\Tmbim4, Mmus\Tmbim7, Mmus\Faim2, Mmus\Tmbim1, Mmus\Grina" "Hsap\FAIM2, Hsap\TMBIM1, Hsap\TMBIM4, Hsap\GRINA" viable FBgn0052093 tRNA:Gln-TTG-1-1 transfer RNA:Glutamine-TTG 1-1 http://flybase.org/reports/FBgn0052093 tRNA_gene CAA codon-amino acid adaptor activity ; GO:0033427 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033427 cytosol ; GO:0005829 | inferred by curator from GO:0033427 "AE002602.trna4-GlnTTG, tRNA:Q:TTG:AE002602, CR32093, chr3L.trna38-GlnTTG, tRNA:Gln-TTG-1-1, tRNA:CR32093, tRNA-Gln-TTG-1-1, CAA" - CR32093 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263782 Hmgcr HMG Coenzyme A reductase http://flybase.org/reports/FBgn0263782 protein_coding_gene "NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR004554, InterPro:IPR004816 hydroxymethylglutaryl-CoA reductase (NADPH) activity ; GO:0004420 | inferred from biological aspect of ancestor with PANTHER:PTN000060346" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002202, InterPro:IPR004554, InterPro:IPR004816, InterPro:IPR009029, InterPro:IPR023074, InterPro:IPR023076, InterPro:IPR023282 isoprenoid biosynthetic process ; GO:0008299 | inferred from electronic annotation with InterPro:IPR004554, InterPro:IPR004816 coenzyme A metabolic process ; GO:0015936 | inferred from electronic annotation with InterPro:IPR002202, InterPro:IPR009029 embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype gonad development ; GO:0008406 | traceable author statement germ cell migration ; GO:0008354 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement germ cell attraction ; GO:0035232 | traceable author statement isoprenoid biosynthetic process ; GO:0008299 | traceable author statement pole cell migration ; GO:0007280 | inferred from mutant phenotype inferred from genetic interaction with hh inferred from genetic interaction with disp pole cell migration ; GO:0007280 | traceable author statement positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D pole cell migration ; GO:0007280 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D sterol biosynthetic process ; GO:0016126 | inferred from biological aspect of ancestor with PANTHER:PTN000060346 ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000731, InterPro:IPR004554 intracellular ; GO:0005622 | traceable author statement peroxisomal membrane ; GO:0005778 | inferred from biological aspect of ancestor with PANTHER:PTN000060347 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000060347 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:5006" "HMGCR, Hmgcr, clb, l(3)04684, HMGCoAr, hmgcr, HMGCoARr, l(3)01152, HMGCR_Dm, CG10367, DmHMG-CoAr, HMGCoAR, bs32f05.y1, HmG-CoAR, Clb, Hmg, BcDNA:LD15354, bro1, hmgc, hmgrc, HMGR" "IPR023282:Hydroxymethylglutaryl-CoA reductase, N-terminal, IPR000731:Sterol-sensing domain, IPR002202:Hydroxymethylglutaryl-CoA reductase, class I/II, IPR004554:Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type, IPR004816:Hydroxymethylglutaryl-CoA reductase, metazoan, IPR009029:Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain, IPR009023:Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain, IPR023074:Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain, IPR023076:Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site" CG10367 11-Aug-17 DroID_v2017_08 "Drer\hmgcra, Drer\hmgcrb" "Scer\HMG2, Scer\HMG1" Cele\hmgr-1 Xtro\hmgcr Mmus\Hmgcr Hsap\HMGCR " embryonic stage , embryonic stage | stage 12-17 , embryonic stage -- adult stage , larval stage&&pupal stage&&adult stage " " embryonic/larval midgut

, ventral midline | restricted

, fat body/gonad primordium

, germline cell | primordium

, parasegment 11 | restricted

, parasegment 12 | restricted

, embryonic/larval foregut

, parasegment 10 | restricted

, dorsal vessel primordium

, embryonic/larval salivary gland

, embryonic/larval hindgut

" DRSC16704 IEK -1.822302564 -2.013714207 -1.792401913 -3.193453556 -1.993892285 -0.286724655 FBgn0263002 CR43310 - http://flybase.org/reports/FBgn0263002 pseudogene_attribute - - - CR43310 - CR43310 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050423 CG30423 - http://flybase.org/reports/FBgn0050423 protein_coding_gene receptor binding ; GO:0005102 | inferred from sequence or structural similarity with HGNC:29477 late endosome to vacuole transport via multivesicular body sorting pathway ; GO:0032511 | inferred from biological aspect of ancestor with PANTHER:PTN000248323 negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from sequence or structural similarity with HGNC:29477 negative regulation of protein localization to cell surface ; GO:2000009 | inferred from biological aspect of ancestor with PANTHER:PTN000248323 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000248323 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:29477 "BcDNA:RH04491, CG30423" IPR007262:Vacuolar protein sorting 55 CG30423 11-Aug-17 DroID_v2017_08 "Drer\zgc:92045, Drer\leprot, Drer\LOC100538044" Scer\VPS55 Cele\C30B5.2 Xtro\leprot "Mmus\Leprotl1, Mmus\Leprot" "Hsap\LEPROT, Hsap\LEPROTL1" viable FBgn0065287 l(2)SH2020 lethal (2) SH2020 http://flybase.org/reports/FBgn0065287 gene - - - "l(2)SH2020, l(2)SH2 2020" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262252 mir-965 mir-965 stem loop http://flybase.org/reports/FBgn0262252 miRNA_gene - histoblast morphogenesis ; GO:0007488 | inferred from mutant phenotype cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype - "miR-965, mir-965, 965, MIR-965, CR42959, dme-miR-965" - CR42959 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male,visible,lethal - all die before end of pupal stage,some die during pupal stage" "eye,wing" FBgn0065956 l(2)SH0057 lethal (2) SH0057 http://flybase.org/reports/FBgn0065956 gene - - - "l(2)SH0057, l(2)SH2 0057" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004842 RYa-R RYamide receptor http://flybase.org/reports/FBgn0004842 "FBgn0044364, FBgn0044365" protein_coding_gene neuropeptide Y receptor activity ; GO:0004983 | inferred from electronic annotation with InterPro:IPR000611 peptide receptor activity ; GO:0001653 | inferred from physical interaction with RYa neuropeptide receptor activity ; GO:0008188 | inferred from sequence model "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000611 cell surface receptor signaling pathway ; GO:0007166 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000611, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "CG5811/107368, CG5811, PR4, anon-WO0131005.15, anon-WO0131005.13, NepYr, Dm RYa-R, RYa-R, ATR, dNepYr" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000611:Neuropeptide Y receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG5811 11-Aug-17 DroID_v2017_08 "Drer\npffr2a, Drer\npy7r, Drer\si:dkey-27p18.2, Drer\npy8br" - "Cele\npr-22, Cele\npr-12, Cele\srsx-9, Cele\npr-6, Cele\npr-11, Cele\npr-1, Cele\npr-5, Cele\npr-35, Cele\npr-2, Cele\C30B5.7, Cele\gnrr-7" "Xtro\qrfpr, Xtro\gpr83, Xtro\npy2r" "Mmus\Npffr2, Mmus\Gpr165, Mmus\Pgr15l, Mmus\Gpr83, Mmus\Npy2r, Mmus\Qrfpr, Mmus\Npy4r, Mmus\Npy6r" "Hsap\NPY2R, Hsap\LOC105379861, Hsap\NPFFR1, Hsap\GPR83, Hsap\QRFPR, Hsap\NPFFR2" "viable,fertile" FBgn0260020 romeo-y-julieta romeo y julieta http://flybase.org/reports/FBgn0260020 gene - - - romeo-y-julieta - - 11-Aug-17 DroID_v2017_08 - - - - - - chorion | germline clone FBgn0027160 l(2)MZ1131 lethal (2) MZ1131 http://flybase.org/reports/FBgn0027160 - gene - - - l(2)MZ1131 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265764 CR44571 - http://flybase.org/reports/FBgn0265764 non_protein_coding_gene - - - CR44571 - CR44571 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260247 GSd209 - http://flybase.org/reports/FBgn0260247 gene - - - GSd209 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0038592 CG18599 - http://flybase.org/reports/FBgn0038592 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - CG18599 "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG18599 11-Aug-17 DroID_v2017_08 "Drer\noto, Drer\emx1, Drer\emx3, Drer\emx2, Drer\vax1, Drer\vax2" - "Cele\alr-1, Cele\duxl-1, Cele\ceh-5, Cele\ceh-87, Cele\ceh-100" "Xtro\not, Xtro\emx2, Xtro\emx1.2, Xtro\vax1" "Mmus\Pitx3, Mmus\Noto, Mmus\Emx1, Mmus\Vax2, Mmus\Vax1, Mmus\Emx2" "Hsap\EMX1, Hsap\VAX1, Hsap\VAX2, Hsap\EMX2, Hsap\NOTO" FBgn0262976 lawc leg arista wing complex http://flybase.org/reports/FBgn0262976 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available polytene chromosome puff ; GO:0005703 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay "CG32711, lawC, l(1)7Ea, lawc, BcDNA:RH09582" - CG32711 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034481 CG11041 - http://flybase.org/reports/FBgn0034481 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - CG11041 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR014837:EF-hand, Ca insensitive" CG11041 11-Aug-17 DroID_v2017_08 "Drer\cabp7b, Drer\pvalb6, Drer\cabp5b, Drer\rhbdl3, Drer\tnnc1a, Drer\calm3a, Drer\calb2b, Drer\calb1, Drer\pvalb2, Drer\calml4b, Drer\calm1b, Drer\calm1a, Drer\calml4a, Drer\caln1, Drer\efcab2, Drer\efcab11, Drer\caln2, Drer\calb2a, Drer\calm2a, Drer\si:ch211-197n1.2, Drer\scgn, Drer\tnnc1b, Drer\cabp2a, Drer\pvalb1, Drer\pvalb4, Drer\efcab6, Drer\cabp1a, Drer\cabp5a, Drer\calm2b, Drer\calm3b, Drer\pvalb8, Drer\tnnc2, Drer\pvalb3, Drer\pvalb9" "Scer\MLC1, Scer\CMD1, Scer\CDC31, Scer\MLC2" "Cele\cal-7, Cele\T02G5.3, Cele\cal-2" "Xtro\calm1, Xtro\ocm, Xtro\calb1, Xtro\calm2, Xtro\pvalb, Xtro\pvalb.2, Xtro\tnnc2, Xtro\ocm.2, Xtro\LOC548651, Xtro\tnnc1, Xtro\pgm1, Xtro\cabp7, Xtro\efcab6, Xtro\calml4, Xtro\scgn, Xtro\pvalb.1, Xtro\cabp4" "Mmus\Efcab7, Mmus\Cabp1, Mmus\Ocm, Mmus\Calb2, Mmus\Efcab11, Mmus\Calb1, Mmus\Tnnc1, Mmus\Calml3, Mmus\Pvalb, Mmus\Scgn, Mmus\Cabp7, Mmus\Rhbdl3, Mmus\Cabp2, Mmus\Calml4, Mmus\Calm4, Mmus\Caln1, Mmus\Cabp4, Mmus\Calm1, Mmus\Cabp5, Mmus\Efcab9, Mmus\Calm3, Mmus\Efcab6, Mmus\Tnnc2, Mmus\Calm2, Mmus\Spata21, Mmus\1700023F06Rik, Mmus\Efcab3, Mmus\Efcab2" "Hsap\CALB1, Hsap\CABP1, Hsap\SPATA21, Hsap\TNNC2, Hsap\CABP5, Hsap\CALM3, Hsap\OCM2, Hsap\CALM2, Hsap\CALM1, Hsap\CABP7, Hsap\SCGN, Hsap\OCM, Hsap\TNNC1, Hsap\EFCAB2, Hsap\EFCAB3, Hsap\CABP4, Hsap\CALML5, Hsap\EFCAB11, Hsap\PVALB, Hsap\EFCAB9, Hsap\EFCAB13, Hsap\CALN1, Hsap\RHBDL3, Hsap\EFCAB6, Hsap\CABP2, Hsap\CALML4, Hsap\EFCAB7, Hsap\CALB2, Hsap\CALML6, Hsap\CALML3" FBgn0037553 CG18249 - http://flybase.org/reports/FBgn0037553 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CT41336, CG18249" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG18249 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014379 rdgE retinal degeneration E http://flybase.org/reports/FBgn0014379 - gene - - - rdgE - - 11-Aug-17 DroID_v2017_08 - - - - - - "visual behavior defective,recessive" "retina,ommatidium,rhabdomere,photoreceptor cell" FBgn0263027 CG43322 - http://flybase.org/reports/FBgn0263027 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "retrograde transport, vesicle recycling within Golgi ; GO:0000301 | inferred from biological aspect of ancestor with PANTHER:PTN000613642 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000613642 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000613642 Golgi vesicle prefusion complex stabilization ; GO:0048213 | inferred from biological aspect of ancestor with PANTHER:PTN000613642" Golgi transport complex ; GO:0017119 | inferred from biological aspect of ancestor with PANTHER:PTN000613642 "CG43322, CG13776" "IPR018961:DnaJ homologue, subfamily C, member 28, conserved domain, IPR001623:DnaJ domain" CG43322 11-Aug-17 DroID_v2017_08 Drer\dnajc28 - - Xtro\dnajc28 Mmus\Dnajc28 Hsap\DNAJC28 "viable,fertile" FBgn0264512 CR43911 - http://flybase.org/reports/FBgn0264512 non_protein_coding_gene - - - CR43911 - CR43911 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033469 CG12133 - http://flybase.org/reports/FBgn0033469 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP15, CG12133" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG12133 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\f9a, Drer\f10" - "Cele\svh-1, Cele\try-3, Cele\try-1" Xtro\masp2 "Mmus\F9, Mmus\F10, Mmus\Klk1b5, Mmus\Proz, Mmus\Klk1b9" "Hsap\CMA1, Hsap\PROZ, Hsap\C1S" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0039904 Hcf Host cell factor http://flybase.org/reports/FBgn0039904 protein_coding_gene transcription coactivator activity ; GO:0003713 | traceable author statement chromatin binding ; GO:0003682 | inferred from direct assay histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay "histone H3 acetylation ; GO:0043966 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay histone H3-K4 methylation ; GO:0051568 | inferred by curator from GO:0044666,GO:0048188 positive regulation of growth ; GO:0045927 | inferred from genetic interaction with Myc histone H4 acetylation ; GO:0043967 | inferred from direct assay" MLL3/4 complex ; GO:0044666 | inferred from direct assay Set1C/COMPASS complex ; GO:0048188 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay MLL1/2 complex ; GO:0044665 | inferred from sequence or structural similarity with HGNC:4839 nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:4839 inferred from direct assay "HCF, dHCF, CG1710, anon-WO0172774.48, Hcf, dHcf1, dHcf, Hcf1, HCF_DROME, HCF1" "IPR003961:Fibronectin type III, IPR006652:Kelch repeat type 1, IPR015915:Kelch-type beta propeller, IPR013783:Immunoglobulin-like fold" CG1710 11-Aug-17 DroID_v2017_08 "Drer\hcfc1a, Drer\klhdc4, Drer\rabepk, Drer\hcfc1b, Drer\hcfc2" "Scer\KEL3, Scer\KEL1, Scer\KEL2" "Cele\hcf-1, Cele\F53E4.1, Cele\Y50D7A.1" "Xtro\hcfc2, Xtro\hcfc1" "Mmus\Klhdc4, Mmus\Hcfc1, Mmus\Hcfc2, Mmus\Fbxo42, Mmus\Rabepk, Mmus\Lztr1, Mmus\Klhdc3" "Hsap\FBXO42, Hsap\HCFC2, Hsap\RABEPK, Hsap\KLHDC3, Hsap\KLHDC4, Hsap\LZTR1, Hsap\HCFC1" "male semi-sterile,female sterile,small body,decreased cell size,increased cell death,partially lethal - majority die,some die during pupal stage,viable,fertile,visible,female limited,lethal,male,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage" "dorsal appendage,egg chamber,wing,ovary,egg,wing disc,wing vein,ectopic,sex comb tooth,humeral bristle,posterior scutellar bristle,female,tergite,anterior compartment,posterior compartment" DRSC17143 K -1.20914844 -0.862377447 -0.220311302 -0.467915374 2.283467786 0.255509094 FBgn0000544 ecl echinus-like http://flybase.org/reports/FBgn0000544 - gene - - - ecl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000817 fs(1)K741 female sterile (1) K741 http://flybase.org/reports/FBgn0000817 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available fs(1)K741 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,heat sensitive" FBgn0267278 CR45714 - http://flybase.org/reports/FBgn0267278 non_protein_coding_gene - - - CR45714 - CR45714 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034247 CG6484 - http://flybase.org/reports/FBgn0034247 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG6484 "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG6484 11-Aug-17 DroID_v2017_08 "Drer\slc2a6, Drer\slc2a12, Drer\si:dkey-229d11.5, Drer\si:ch1073-263o8.2, Drer\LOC797974, Drer\LOC101882338, Drer\slc2a8, Drer\slc2a10, Drer\slc2a13b" "Scer\GEX1, Scer\MAL11, Scer\HXT17, Scer\MPH2, Scer\HXT11, Scer\VBA4, Scer\ITR1, Scer\VBA2, Scer\RGT2, Scer\YDL199C, Scer\HXT8, Scer\MAL31, Scer\SGE1, Scer\YMR279C, Scer\YFL040W, Scer\HXT16, Scer\HXT3, Scer\AZR1, Scer\SNF3, Scer\ITR2, Scer\STL1, Scer\HXT14, Scer\HXT4, Scer\VBA3, Scer\HXT2, Scer\HXT9, Scer\VBA1, Scer\ENB1, Scer\HXT5, Scer\HXT15, Scer\MPH3, Scer\GEX2, Scer\HXT10, Scer\HXT1, Scer\HXT6, Scer\GAL2, Scer\YDR387C, Scer\ATR1, Scer\HXT13, Scer\HXT7, Scer\VBA5" "Cele\M01G12.14, Cele\Y66D12A.21, Cele\ZK829.9, Cele\M01G12.9" "Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a12, Xtro\slc2a6" "Mmus\Slc2a12, Mmus\Slc2a6, Mmus\Slc2a10, Mmus\Tm2d1, Mmus\Pate3, Mmus\Acrv1, Mmus\Gm7257, Mmus\Slc2a13, Mmus\Slc2a8, Mmus\Pate4, Mmus\Pate1, Mmus\1700013H16Rik, Mmus\Gm5615, Mmus\Gm17689" "Hsap\ACRV1, Hsap\PATE3, Hsap\SLC2A10, Hsap\PATE4, Hsap\TM2D1, Hsap\SLC2A8, Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SLC2A12, Hsap\PATE1" viable FBgn0051781 CR31781 - http://flybase.org/reports/FBgn0051781 non_protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG15131, CG15132, BcDNA:GH27691, BcDNA:LP04536, CG31781, CR31781" - CR31781 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" chaeta FBgn0030881 CG12985 - http://flybase.org/reports/FBgn0030881 protein_coding_gene - developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 - CG12985 IPR007999:Protein of unknown function DUF745 CG12985 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19505 K -0.222199201 0.654048053 -0.034700822 -0.987846451 2.217622675 0.251970327 FBgn0259347 EP-608 - http://flybase.org/reports/FBgn0259347 gene - - - EP-608 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,chaeta,ectopic" FBgn0030671 CG8134 - http://flybase.org/reports/FBgn0030671 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8134 - CG8134 11-Aug-17 DroID_v2017_08 Drer\zgc:101679 - - - "Mmus\F8a, Mmus\Lamtor2" "Hsap\LAMTOR2, Hsap\F8A1, Hsap\F8A3, Hsap\F8A2" viable FBgn0027141 l(3)76BCa lethal (3) 76BCa http://flybase.org/reports/FBgn0027141 - gene - - - l(3)76BCa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259151 CG42266 - http://flybase.org/reports/FBgn0259151 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42266, CG31737, CG18115, DS02740.19, BG:DS02740.19, CG31818" - CG42266 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259327 C504 - http://flybase.org/reports/FBgn0259327 gene - - - C504 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin" FBgn0041258 DyrkH DyrkH http://flybase.org/reports/FBgn0041258 gene - - - DyrkH - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001094 gau gauze http://flybase.org/reports/FBgn0001094 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gau - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0266195 Tgs1 Trimethylguanosine synthase 1 http://flybase.org/reports/FBgn0266195 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR019012 RNA methylation ; GO:0001510 | inferred from electronic annotation with InterPro:IPR019012 7-methylguanosine RNA capping ; GO:0009452 | inferred from mutant phenotype - "CG44890, tatl, dORF, TGS1, CG31241, Tgs1, l(3)S096713, 0967/13, dtl, DTLd, Dromel_CG31241_FBtr0083570_dtl_mORF, Dtl, CT24102, CG8045, DTL, tgs1" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR019012:RNA cap guanine-N2 methyltransferase" CG44890 11-Aug-17 DroID_v2017_08 Drer\tgs1 Scer\TGS1 Cele\T08G11.4 Xtro\tgs1 Mmus\Tgs1 Hsap\TGS1 FBgn0267209 CR45649 - http://flybase.org/reports/FBgn0267209 non_protein_coding_gene - - - CR45649 - CR45649 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020591 anon-57Cf anon-57Cf http://flybase.org/reports/FBgn0020591 - gene - - - anon-57Cf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265145 CR44214 - http://flybase.org/reports/FBgn0265145 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44214, CR44214" - CR44214 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032053 mRpL51 mitochondrial ribosomal protein L51 http://flybase.org/reports/FBgn0032053 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P0C2B6 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P0C2B6 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:P0C2B6 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial ribosome ; GO:0005761 | inferred from sequence or structural similarity with UniProtKB:P0C2B6 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:P0C2B6 inferred from sequence or structural similarity with UniProtKB:Q86TS9 "CG13098, MRP-L51, mRpL51" "IPR019373:Ribosomal protein L51, mitochondrial" CG13098 11-Aug-17 DroID_v2017_08 Drer\mrpl51 - Cele\mrpl-51 Xtro\mrpl51 Mmus\Mrpl51 Hsap\MRPL51 "viable,visible" trichogen cell DRSC02200 E 0.498324331 -0.576131367 -1.51554978 0.122482273 0.331818201 0.349886873 FBgn0019680 mor(1)11 mortality gene (1)11 http://flybase.org/reports/FBgn0019680 - gene - - - mor(1)11 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0034548 CG13443 - http://flybase.org/reports/FBgn0034548 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13443 - CG13443 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060370 l(3)S138006 lethal (3) S138006 http://flybase.org/reports/FBgn0060370 gene - - - "1380/06, l(3)S138006" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0050157 CG30157 - http://flybase.org/reports/FBgn0050157 protein_coding_gene thiolester hydrolase activity ; GO:0016790 | inferred from sequence or structural similarity with UniProtKB:Q99K23 UFM1 hydrolase activity ; GO:0071567 | inferred from biological aspect of ancestor with PANTHER:PTN000325444 UFM1 hydrolase activity ; GO:0071567 | inferred from sequence or structural similarity with UniProtKB:Q99K23 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30157 "IPR012462:Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2, IPR033502:UfSP1 peptidase" CG30157 11-Aug-17 DroID_v2017_08 "Drer\ufsp2, Drer\ufsp1" - Cele\odr-8 - "Mmus\Ufsp2, Mmus\Ufsp1" "Hsap\UFSP2, Hsap\UFSP1" FBgn0266280 CR44965 - http://flybase.org/reports/FBgn0266280 non_protein_coding_gene - - - CR44965 - CR44965 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259174 Nedd4 Nedd4 http://flybase.org/reports/FBgn0259174 protein_coding_gene Notch binding ; GO:0005112 | inferred from physical interaction with UniProtKB:P07207 protein domain specific binding ; GO:0019904 | inferred from physical interaction with N ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24139 protein domain specific binding ; GO:0019904 | inferred from direct assay ubiquitin-protein transferase activity ; GO:0004842 | non-traceable author statement myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A protein domain specific binding ; GO:0019904 | inferred from physical interaction with comm positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q23985 receptor internalization ; GO:0031623 | inferred from physical interaction with UniProtKB:Q24139 positive regulation of receptor internalization ; GO:0002092 | inferred from mutant phenotype positive regulation of synapse assembly ; GO:0051965 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype receptor internalization ; GO:0031623 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | NOT inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "NEDD4, Nedd4, CG42279, CG7555, nedd4, DNedd4, dNedd4-1, dNedd4, CG32184, ACN62428.1" "IPR000008:C2 domain, IPR000569:HECT domain, IPR001202:WW domain" CG42279 11-Aug-17 DroID_v2017_08 "Drer\bag3, Drer\smurf2, Drer\hecw2b, Drer\hecw1b, Drer\yap1, Drer\nedd4l, Drer\wwtr1, Drer\nedd4a, Drer\LOC100334952, Drer\hecw2a, Drer\itcha, Drer\smurf1, Drer\wwp2" "Scer\RSP5, Scer\TOM1" "Cele\wwp-1, Cele\Y92H12A.2" "Xtro\bag3, Xtro\hecw1, Xtro\nedd4l, Xtro\itch, Xtro\wwp2, Xtro\nedd4, Xtro\smurf1" "Mmus\Bag3, Mmus\Wwp2, Mmus\Nedd4l, Mmus\Hecw2, Mmus\Wwp1, Mmus\Yap1, Mmus\Itch, Mmus\Smurf1, Mmus\Smurf2, Mmus\Gas7, Mmus\Hecw1, Mmus\Nedd4" "Hsap\HECW1, Hsap\SMURF2, Hsap\WWP2, Hsap\NEDD4, Hsap\BAG3, Hsap\SMURF1, Hsap\ITCH, Hsap\GAS7, Hsap\NEDD4L, Hsap\WWP1, Hsap\HECW2, Hsap\YAP1" FBgn0019686 lok loki http://flybase.org/reports/FBgn0019686 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay tau-protein kinase activity ; GO:0050321 | inferred from direct assay" peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of sequence-specific DNA binding transcription factor activity ; GO:0051091 | inferred from mutant phenotype signal transduction in response to DNA damage ; GO:0042770 | inferred from biological aspect of ancestor with PANTHER:PTN002389571 apoptotic process ; GO:0006915 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from expression pattern peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement intrinsic apoptotic signaling pathway by p53 class mediator ; GO:0072332 | inferred from genetic interaction with UniProtKB:Q8IMZ4 DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype regulation of DNA repair ; GO:0006282 | inferred from mutant phenotype intrinsic apoptotic signaling pathway in response to DNA damage ; GO:0008630 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype mitotic DNA damage checkpoint ; GO:0044773 | inferred from direct assay cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CHK-2, chk2, CHK2, chk2/lok, mnk, Chk2, MNK, DmCHk2, chk, Dmchk2, DmChk2, Dmnk, 38B.4, LOKI/CHK2, CG10895, Dmnk-S, Dmnk-L, lok, loki, Dmnk/DChk2, 10895" "IPR000253:Forkhead-associated (FHA) domain, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR008984:SMAD/FHA domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG10895 11-Aug-17 DroID_v2017_08 "Drer\chek2, Drer\pskh1, Drer\zmp:0000000881, Drer\dclk2a" "Scer\RAD53, Scer\MEK1, Scer\DUN1" "Cele\chk-2, Cele\pdk-1, Cele\T08D2.7" "Xtro\chek2, Xtro\pskh1, Xtro\dclk3, Xtro\dclk2" "Mmus\Chek2, Mmus\Pskh1, Mmus\Dclk3" "Hsap\DCLK2, Hsap\CHEK2, Hsap\PSKH1, Hsap\DCLK3" " adult stage && oogenesis stage | stage >=S2 , embryonic stage | stage 1,2 , embryonic stage | early , oogenesis stage && adult stage | female , embryonic stage | stage >=3 " " nurse cell

,

ubiquitous , ovary

, pole cell

" " embryonic stage | stage 3,4 "

ubiquitous "visible,increased cell death,radiation sensitive,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,long lived,viable,chemical resistant,decreased cell death,fertile,cell death defective,conditional" "eye,egg chamber | oogenesis stage S8,egg chamber | oogenesis stage S9,egg chamber,nucleus | embryonic stage,mitosis & nuclear chromosome & embryo,spindle | embryonic stage,wing disc,eye disc,conditional,embryonic/larval neuroblast" FBgn0030809 Ubr1 Ubr1 ubiquitin ligase http://flybase.org/reports/FBgn0030809 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR003126 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000486924 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000003416 zinc ion binding ; GO:0008270 | inferred from sequence model" ubiquitin-dependent protein catabolic process via the N-end rule pathway ; GO:0071596 | inferred from biological aspect of ancestor with PANTHER:PTN000486924 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000003416 ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000486924 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000486924 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003416 "CG9086, Ubr1, ubr1, UBR1, UBR1/2" "IPR003126:Zinc finger, UBR-type, IPR003769:Adaptor protein ClpS, core, IPR014719:Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9086 11-Aug-17 DroID_v2017_08 "Drer\ubr1, Drer\ubr2" "Scer\UBR2, Scer\UBR1" Cele\ubr-1 "Xtro\ubr2, Xtro\ubr1, Xtro\fgf13" "Mmus\Ubr1, Mmus\Ubr2" "Hsap\UBR2, Hsap\UBR1" "viable,visible" mesothoracic tergum DRSC20148 I -1.018991161 -2.113807168 -0.814819403 -1.352866079 0.584260609 -0.558454239 FBgn0014061 Su(tor)2-93 Su(tor)2-93 http://flybase.org/reports/FBgn0014061 - gene - - - Su(tor)2-93 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0264466 CR43874 - http://flybase.org/reports/FBgn0264466 non_protein_coding_gene - - - CR43874 - CR43874 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013693 mt:tRNA:Phe-GAA mitochondrial transfer RNA:Phenylalanine-GAA http://flybase.org/reports/FBgn0013693 FBgn0002867 tRNA_gene - - - "CR34082, tRNA[Phe], mtdbD00006307, mt:tRNA:Phe-GAA, mt:tRNA:F" - CR34082 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038160 CG9759 - http://flybase.org/reports/FBgn0038160 protein_coding_gene - - - "BcDNA:GH02603, CG9759" - CG9759 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC16558 K 0.103064008 0.950675518 0.330907812 0.346222806 1.714206161 0.25546411 FBgn0085391 trv trivet http://flybase.org/reports/FBgn0085391 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype" - "BcDNA:RE10833, CG12870, CG12872, Tia1-like, CG34362, trv" IPR000504:RNA recognition motif domain CG34362 11-Aug-17 DroID_v2017_08 "Drer\tia1, Drer\tia1l, Drer\tial1" "Scer\NAM8, Scer\PUB1, Scer\NGR1" "Cele\tiar-3, Cele\tiar-2, Cele\tag-262, Cele\tiar-1, Cele\grld-1" Xtro\tia1 "Mmus\Tial1, Mmus\Tia1, Mmus\Rbm42" "Hsap\RBM42, Hsap\TIAL1, Hsap\TIA1" FBgn0082625 S(CycE[JP])3.3 S(CycE[JP])3.3 http://flybase.org/reports/FBgn0082625 gene - - - S(CycE[JP])3.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033378 tsu tsunagi http://flybase.org/reports/FBgn0033378 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000566947 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with HGNC:9905 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P82804 "regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype inferred from physical interaction with mago RNA splicing ; GO:0008380 | inferred from mutant phenotype oocyte nucleus migration involved in oocyte dorsal/ventral axis specification ; GO:0007312 | inferred from mutant phenotype establishment of pole plasm mRNA localization ; GO:0046595 | traceable author statement negative regulation of transposition, DNA-mediated ; GO:0000335 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from biological aspect of ancestor with PANTHER:PTN000566947 pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | non-traceable author statement microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from biological aspect of ancestor with PANTHER:PTN000566947" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay exon-exon junction complex ; GO:0035145 | inferred from physical interaction with mago catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "Y14, Y14/Tsunagi, CG8781, y14, cg8781, tsu, TSU, Tsu" "IPR000504:RNA recognition motif domain, IPR008111:RNA-binding motif protein 8, IPR033744:RBM8, RNA recognition motif" CG8781 11-Aug-17 DroID_v2017_08 Drer\rbm8a Scer\CTF3 "Cele\rnp-4, Cele\Y82E9BR.2" Xtro\rbm8a Mmus\Rbm8a "Hsap\NCL, Hsap\RBM8A"

"lethal - all die before end of embryonic stage,germline clone,recessive,lethal,some die during embryonic stage,viable,female sterile,cell growth defective,cell lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage" "egg,germline clone,egg chamber,synaptonemal complex | germline clone,germarium region 2b,germarium region 3,dorsal appendage,oocyte nucleus,embryonic/larval brain" FBgn0260596 2L2985 - http://flybase.org/reports/FBgn0260596 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2985 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0065178 l(3)SH007 lethal (3) SH007 http://flybase.org/reports/FBgn0065178 gene - - - "l(3)SH007, l(2)SH3 007" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024267 acd(2)5E8 auditory courtship defective 5E8 http://flybase.org/reports/FBgn0024267 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5E8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective" FBgn0277426 l(3)psg26 - http://flybase.org/reports/FBgn0277426 gene - - - "l(3)psg26, psg26" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035003 CG15873 - http://flybase.org/reports/FBgn0035003 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH184, SP184, CG15873" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG15873 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.8, Drer\LOC103908930" - Cele\try-1 Xtro\tpsab1 Mmus\Cfd "Hsap\PRSS55, Hsap\CFD, Hsap\AZU1, Hsap\GZMK, Hsap\KLK10" FBgn0264502 CG43901 - http://flybase.org/reports/FBgn0264502 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43901, CG11203, CG15207" "IPR011990:Tetratricopeptide-like helical domain, IPR020683:Ankyrin repeat-containing domain" CG43901 11-Aug-17 DroID_v2017_08 "Drer\csrp2, Drer\csrp1b, Drer\csrp1a, Drer\csrp3" Scer\LRG1 Cele\mlp-1 - "Mmus\Csrp2, Mmus\Csrp3, Mmus\Csrp1" "Hsap\CSRP3, Hsap\CSRP2, Hsap\CSRP1" FBgn0085265 CG34236 - http://flybase.org/reports/FBgn0085265 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34236 - CG34236 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267698 Pak p21-activated kinase http://flybase.org/reports/FBgn0267698 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement SH3 domain binding ; GO:0017124 | inferred from physical interaction with dock protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity Rac GTPase binding ; GO:0048365 | inferred from physical interaction with Rac1 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 Rho GTPase binding ; GO:0017048 | inferred from physical interaction with Cdc42" "axon guidance ; GO:0007411 | traceable author statement septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype JNK cascade ; GO:0007254 | non-traceable author statement cell adhesion ; GO:0007155 | inferred from direct assay imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with LIMK1 actin cytoskeleton organization ; GO:0030036 | inferred from biological aspect of ancestor with PANTHER:PTN000685295 dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from expression pattern protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of synapse structure or activity ; GO:0050803 | inferred from mutant phenotype regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from physical interaction with dock dorsal closure ; GO:0007391 | traceable author statement Rac protein signal transduction ; GO:0016601 | non-traceable author statement axon guidance ; GO:0007411 | inferred from genetic interaction with Dscam1 positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype" cell leading edge ; GO:0031252 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay focal adhesion ; GO:0005925 | colocalizes_with inferred from direct assay muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay actin filament ; GO:0005884 | colocalizes_with inferred from direct assay cytoskeleton ; GO:0005856 | inferred from mutant phenotype postsynaptic density ; GO:0014069 | "pak, psg4, Pak, PAK, Pak1, DPAK, DPak1, dPak, CG10295, PAK1, DmPAK1, dpak, pak1, Dpak, DPak, PaK, dPAK1, PAK2, Dpak1, D-Pak, p65[PAK], dPAK, dpak1, l(3)psg4, PAK-1" "IPR033923:p21 activated kinase binding domain, IPR000095:CRIB domain, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG10295 11-Aug-17 DroID_v2017_08 "Drer\pak1, Drer\pak2a, Drer\pak6b, Drer\pak4, Drer\LOC100536197, Drer\pak2b" "Scer\NPR1, Scer\SKM1, Scer\STE20, Scer\CLA4" "Cele\pak-1, Cele\max-2, Cele\pak-2" "Xtro\pak6, Xtro\pak4, Xtro\pak2, Xtro\pak3, Xtro\pak7, Xtro\pak1" "Mmus\Pak6, Mmus\Pak3, Mmus\Pak2, Mmus\Pak7, Mmus\Pak1, Mmus\Pak4" "Hsap\PAK2, Hsap\PAK4, Hsap\PAK6, Hsap\PAK1, Hsap\PAK5, Hsap\PAK3" " embryonic stage | stage >=15 , embryonic stage | stage 11-14 , embryonic stage , embryonic stage -- adult stage " " embryonic/larval dorsal vessel

, embryonic central nervous system

, amnioserosa | surrounding

,

ubiquitous , muscle attachment site

" " embryonic stage | late , embryonic stage , embryonic stage | stage 11-14 , embryonic stage | stage >=12 " " embryonic/larval dorsal vessel

,

ubiquitous , amnioserosa | surrounding

, posterior commissure

, muscle attachment site

, embryonic central nervous system

, anterior commissure

, longitudinal connective

" FBgn0266491 SclA Sarcolamban A http://flybase.org/reports/FBgn0266491 protein_coding_gene - regulation of cardiac muscle contraction ; GO:0055117 | inferred from mutant phenotype T-tubule ; GO:0030315 | inferred from direct assay "pncr003:2L, ORF-A, pncr:003:2L, mel1, BcDNA:RE28911, BEST:LP06756, CR31696, SclA, scl, pncr003:2L ORFA, CG45090, pncr003, sclA" - CG45090 11-Aug-17 DroID_v2017_08 - - - - - - adult heart FBgn0031655 Marcal1 Marcal1 http://flybase.org/reports/FBgn0031655 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 ATP-dependent four-way junction helicase activity ; GO:1990163 | inferred from direct assay annealing helicase activity ; GO:0036310 | inferred from direct assay DNA-dependent ATPase activity ; GO:0008094 | inferred from sequence or structural similarity with UniProtKB:Q9NZC9 annealing helicase activity ; GO:0036310 | inferred from sequence or structural similarity with UniProtKB:Q9NZC9 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:Q9NZC9 DNA metabolic process ; GO:0006259 | inferred from sequence or structural similarity with UniProtKB:Q9NZC9 replication fork reversal ; GO:0071932 | NOT inferred from direct assay DNA rewinding ; GO:0036292 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9NZC9 "CG3753, Marcal1, Marca1, HARP, dmHARP, MARCAL1" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR010003:HARP domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3753 11-Aug-17 DroID_v2017_08 "Drer\smarcal1, Drer\zranb3" Scer\MOT1 Cele\smrc-1 "Xtro\zranb3, Xtro\smarcal1" "Mmus\Smarcal1, Mmus\Zranb3" "Hsap\ZRANB3, Hsap\SMARCAL1" "short lived,heat sensitive,visible,viable" "egg,heat sensitive,wing vein,ectopic,trichogen cell" FBgn0085571 CG41245 - http://flybase.org/reports/FBgn0085571 protein_coding_gene - - - CG41245 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022806 E(var)19 E(var)19 http://flybase.org/reports/FBgn0022806 - gene - - - E(var)19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0260392 CG42518 - http://flybase.org/reports/FBgn0260392 protein_coding_gene - - - "CG5134, CG42518" - CG42518 11-Aug-17 DroID_v2017_08 Drer\si:ch211-162e15.3 - - - - - FBgn0034728 rad50 rad50 http://flybase.org/reports/FBgn0034728 protein_coding_gene adenylate kinase activity ; GO:0004017 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 double-stranded telomeric DNA binding ; GO:0003691 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 G-quadruplex DNA binding ; GO:0051880 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 single-stranded telomeric DNA binding ; GO:0043047 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 3'-5' exonuclease activity ; GO:0008408 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000429848 single-stranded DNA endodeoxyribonuclease activity ; GO:0000014 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000429848 ATP-dependent DNA helicase activity ; GO:0004003 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000429848 double-stranded DNA binding ; GO:0003690 | inferred from sequence or structural similarity with UniProtKB:P12753 telomere maintenance via telomerase ; GO:0007004 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 chromosome organization ; GO:0051276 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred from mutant phenotype telomere maintenance via recombination ; GO:0000722 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 nucleic acid phosphodiester bond hydrolysis ; GO:0090305 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 reciprocal meiotic recombination ; GO:0007131 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 telomere maintenance ; GO:0000723 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 telomere maintenance via recombination ; GO:0000722 | inferred from mutant phenotype DNA duplex unwinding ; GO:0032508 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 protein localization ; GO:0008104 | inferred from mutant phenotype double-strand break repair ; GO:0006302 | inferred from mutant phenotype chromosome organization involved in meiotic cell cycle ; GO:0070192 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 "Mre11 complex ; GO:0030870 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 site of double-strand break ; GO:0035861 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 nucleus ; GO:0005634 | inferred from mutant phenotype condensed nuclear chromosome ; GO:0000794 | inferred from biological aspect of ancestor with PANTHER:PTN000429848 condensed chromosome ; GO:0000793 | inferred from direct assay Mre11 complex ; GO:0030870 | traceable author statement nuclear chromosome, telomeric region ; GO:0000784 | inferred from biological aspect of ancestor with PANTHER:PTN000429848" "Rad50, Dmrad50, CG6339, rad50, RAD50, 6339" "IPR004584:DNA repair protein Rad50, eukaryotes, IPR013134:RAD50, zinc hook, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG6339 11-Aug-17 DroID_v2017_08 Drer\rad50 Scer\RAD50 Cele\rad-50 "Xtro\rad50, Xtro\cit" Mmus\Rad50 Hsap\RAD50 "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,radiation sensitive,viable" "wing margin,mitosis & nuclear chromosomeX58-8),chromosome, telomeric regionX58-8),eye,wing,chaeta,wing disc,mitosis & nuclear chromosome,chromosome, telomeric region,condensed chromosome" FBgn0025557 anon-88Ba anon-88Ba http://flybase.org/reports/FBgn0025557 - gene - - - "c3.5/c4.4, anon-88Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023515 CG14814 - http://flybase.org/reports/FBgn0023515 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available DNA demethylation ; GO:0080111 | inferred from biological aspect of ancestor with PANTHER:PTN000559411 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000559411 "EG:63B12.6, CG14814" IPR006640:SprT-like CG14814 11-Aug-17 DroID_v2017_08 Drer\acrc Scer\FYV8 "Cele\F11E6.7, Cele\ZK328.4" - - Hsap\GCNA "viable,fertile,lethal" FBgn0027588 GCS2alpha Glucosidase 2 alpha subunit http://flybase.org/reports/FBgn0027588 - protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR000322 carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000322, InterPro:IPR011013" endomembrane system ; GO:0012505 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "clot#312, BcDNA:GH04962, CG14476, GCS2alpha" "IPR025887:Glycoside hydrolase family 31, N-terminal domain, IPR000322:Glycoside hydrolase family 31, IPR011013:Galactose mutarotase-like domain, IPR017853:Glycoside hydrolase superfamily" CG14476 11-Aug-17 DroID_v2017_08 "Drer\zgc:171967, Drer\ganab, Drer\ganc" Scer\ROT2 "Cele\aagr-4, Cele\aagr-3" "Xtro\ganab, Xtro\ganc" "Mmus\Ganab, Mmus\Ganc" "Hsap\GANAB, Hsap\GANC" "partially lethal - majority die,some die during pupal stage" FBgn0053764 CG33764 - http://flybase.org/reports/FBgn0053764 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33764 IPR010512:Protein of unknown function DUF1091 CG33764 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051779 Acp24A4 Accessory gland protein 24A4 http://flybase.org/reports/FBgn0051779 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG31779, Acp24A4" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG31779 11-Aug-17 DroID_v2017_08 "Drer\spint1a, Drer\si:dkey-117n7.5, Drer\wfikkn2b, Drer\wfikkn1, Drer\wfikkn2a, Drer\spint2, Drer\si:dkeyp-73b11.8, Drer\spint1b, Drer\tfpia, Drer\tfpi2, Drer\col6a4a, Drer\ambp" - "Cele\T22F7.5, Cele\T21D12.12, Cele\mlt-11" "Xtro\tfpi2, Xtro\spint2, Xtro\spint1, Xtro\ambp" "Mmus\Tfpi, Mmus\Spint4, Mmus\Wfdc6b, Mmus\Spint2, Mmus\Wfdc6a, Mmus\Spint1, Mmus\Wfdc8, Mmus\Spint3, Mmus\Wfikkn1, Mmus\Eppin, Mmus\Ambp, Mmus\Spint5, Mmus\Tfpi2, Mmus\Wfikkn2" "Hsap\EPPIN-WFDC6, Hsap\SPINT4, Hsap\WFIKKN2, Hsap\SPINT2, Hsap\WFDC8, Hsap\TFPI2, Hsap\SPINT3, Hsap\SPINT1, Hsap\WFDC6, Hsap\TFPI, Hsap\WFIKKN1, Hsap\AMBP" viable DRSC22352 K -0.077597493 0.1092658 0.384336365 0.05940326 2.152043177 -0.185223184 FBgn0024908 anon-99Fa anon-99Fa http://flybase.org/reports/FBgn0024908 - gene - - - "K7, anon-99Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085366 CG34337 - http://flybase.org/reports/FBgn0085366 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34337 - CG34337 11-Aug-17 DroID_v2017_08 "Drer\slc5a6a, Drer\slc5a8, Drer\slc5a6b, Drer\slc5a12, Drer\slc5a8l, Drer\slc5a5" - - "Xtro\slc5a5, Xtro\slc5a12, Xtro\slc5a2, Xtro\slc5a8" "Mmus\Slc5a5, Mmus\Slc5a6, Mmus\Slc5a8, Mmus\Slc5a12" "Hsap\SLC5A12, Hsap\SLC5A8, Hsap\SLC5A6, Hsap\SLC5A5" FBgn0017465 TfIIH-29 Transcription factor IIH-29kD http://flybase.net/reports/FBgn0017465.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TFIIH, TfIIH" 11-Aug-17 DroID_v2017_08 FBgn0053665 CG33665 - http://flybase.org/reports/FBgn0053665 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33665 - CG33665 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053681 CG33681 - http://flybase.org/reports/FBgn0053681 protein_coding_gene - - - "BG:DS01514.3, DS01514.3, CG33681" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043388 EP383 EP383 http://flybase.org/reports/FBgn0043388 gene - - - "EP0383, EP383" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "scutellar bristle,trichogen cell,tormogen cell,embryonic/larval salivary gland" FBgn0031135 CR11235 - http://flybase.org/reports/FBgn0031135 pseudogene_attribute - - - "CR11235, CG11235" - CR11235 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003661 syndrome syndrome http://flybase.org/reports/FBgn0003661 - gene - - - "syndrome, syn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male sterile,viable,reduced" FBgn0050196 CG30196 - http://flybase.org/reports/FBgn0050196 protein_coding_gene - - - "CG13514, CG30196" IPR006629:LPS-induced tumour necrosis factor alpha factor CG30196 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-202h22.8, Drer\cdip1, Drer\si:ch211-202h22.7, Drer\litaf, Drer\si:ch211-157c3.4, Drer\si:dkeyp-75b4.8, Drer\si:ch211-202h22.9" - "Cele\B0348.2, Cele\Y37D8A.8, Cele\Y87G2A.18, Cele\Y37D8A.26, Cele\Y40H7A.11, Cele\Y37D8A.6, Cele\B0348.1, Cele\F36G3.3, Cele\Y22D7AL.15, Cele\F16F9.1, Cele\C08E8.1" - "Mmus\Cdip1, Mmus\Litaf" "Hsap\CDIP1, Hsap\LITAF" viable FBgn0036364 CG14109 - http://flybase.org/reports/FBgn0036364 protein_coding_gene - - - CG14109 - CG14109 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065691 l(2)SH0643 lethal (2) SH0643 http://flybase.org/reports/FBgn0065691 gene - - - "l(2)SH0643, l(2)SH2 0643" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010021 E(Dl)9P39.8 Enhancer of Delta 9P39.8 http://flybase.org/reports/FBgn0010021 - gene - - - E(Dl)9P39.8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003441 smk smoky http://flybase.org/reports/FBgn0003441 - gene - - - "sm, smk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,good,visible,recessive,female sterile,heat sensitive,body color defective" adult thorax FBgn0262697 Su(VGlut)B37 - http://flybase.org/reports/FBgn0262697 gene - - - "Su(VGlut)B37, B37" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044006 Su(rst)C103 Su(rst)C103 http://flybase.org/reports/FBgn0044006 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C103, Su(rst)C103" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0000271 ccw concave wing http://flybase.org/reports/FBgn0000271 - gene - - - ccw - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile" wing FBgn0037065 CG12974 - http://flybase.org/reports/FBgn0037065 protein_coding_gene - - - CG12974 - CG12974 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028198 l(3)S020514a lethal (3) S020514a http://flybase.org/reports/FBgn0028198 gene - - - "0205/14, l(3)S020514, l(3)S020514a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266743 CR45216 - http://flybase.org/reports/FBgn0266743 non_protein_coding_gene - - - CR45216 - CR45216 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005179 l(2)S1A lethal of Seto 1A http://flybase.org/reports/FBgn0005179 - gene - - - l(2)S1A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "adult garland cell,pupa" FBgn0062249 Tel Telomere elongation http://flybase.org/reports/FBgn0062249 gene molecular_function ; GO:0003674 | no biological data available telomere maintenance ; GO:0000723 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Tel, Gaiano strain" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" "polytene chromosome, telomeric region" FBgn0015869 anon-37Ca anon-37Ca http://flybase.org/reports/FBgn0015869 - gene - - - anon-37Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017388 l(1)15Dc lethal (1) 15Dc http://flybase.org/reports/FBgn0017388 - gene - - - l(1)15Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085810 CR41597 - http://flybase.org/reports/FBgn0085810 pseudogene_attribute - - - CR41597 - CR41597 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262427 mir-1016 mir-1016 stem loop http://flybase.org/reports/FBgn0262427 miRNA_gene - - - "dme-mir-1016, mir-1016, CR42981, miR-1016" - CR42981 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000590 e(sei) enhancer of seizure http://flybase.org/reports/FBgn0000590 - gene molecular_function ; GO:0003674 | no biological data available mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available e(sei) - - 11-Aug-17 DroID_v2017_08 - - - - - - "bang sensitive,recessive,hyperactive,uncoordinated" FBgn0026604 Act88F::Scer\ACT1 Act88F::Scer\act1 http://flybase.org/reports/FBgn0026604 - engineered_fusion_gene - - - "Act88F::Scer\act1, Act88F::Scer\ACT1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000713 fm fine macros http://flybase.org/reports/FBgn0000713 - gene - - - fm - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority live,visible,male fertile,viable,male,reduced" "abdomen,macrochaeta,adult abdomen" FBgn0032631 CG15140 - http://flybase.org/reports/FBgn0032631 protein_coding_gene - - - CG15140 - CG15140 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003745 trd tridenticle http://flybase.org/reports/FBgn0003745 - gene - - - trd - - 11-Aug-17 DroID_v2017_08 - - - - - - denticle FBgn0000895 fs(1)M95 female sterile (1) M95 http://flybase.org/reports/FBgn0000895 - gene - - - fs(1)M95 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0030655 CG9213 - http://flybase.org/reports/FBgn0030655 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011146 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32585, CG9213" "IPR006767:Cwf19-like protein, C-terminal domain-2, IPR006768:Cwf19-like, C-terminal domain-1, IPR011146:HIT-like domain" CG9213 11-Aug-17 DroID_v2017_08 Drer\cwf19l2 Scer\DRN1 Cele\B0361.2 Xtro\cwf19l2 Mmus\Cwf19l2 Hsap\CWF19L2 FBgn0028190 l(3)S023426 lethal (3) S023426 http://flybase.org/reports/FBgn0028190 gene - - - "0234/26, l(3)S023426" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083252 E(smoDN)G Enhancer of smoDN group G http://flybase.org/reports/FBgn0083252 gene - smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "Group G, E(smoDN)G" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,somatic clone,lethal" "eye,somatic clone,eye photoreceptor cell,ommatidium,wing,wing margin" FBgn0031703 CG12512 - http://flybase.org/reports/FBgn0031703 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 peroxisome ; GO:0005777 | inferred from sequence model microtubule associated complex ; GO:0005875 | inferred from direct assay CG12512 "IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site" CG12512 11-Aug-17 DroID_v2017_08 "Drer\acsf3, Drer\acsf2" Scer\PCS60 "Cele\acs-21, Cele\acs-1, Cele\acs-7, Cele\acs-16, Cele\acs-14, Cele\acs-12, Cele\acs-2, Cele\acs-11" "Xtro\acsf2, Xtro\acsf3" "Mmus\Acsf2, Mmus\Acsf3" "Hsap\ACSF3, Hsap\ACSF2" FBgn0040155 l(1)G0464 lethal (1) G0464 http://flybase.org/reports/FBgn0040155 gene - - - l(1)G0464 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile" FBgn0031061 CG14232 - http://flybase.org/reports/FBgn0031061 protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 "anon-18DEc, CG14232" "IPR000582:Acyl-CoA-binding protein, ACBP, IPR009038:GOLD domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle" CG14232 11-Aug-17 DroID_v2017_08 "Drer\tmed8, Drer\zgc:162964, Drer\acbd3" - Cele\Y41E3.7 "Xtro\tmed8, Xtro\acbd3" "Mmus\Tmed8, Mmus\Acbd3" "Hsap\ACBD3, Hsap\TMED8" viable DRSC19588 K 0.797774322 0.643074076 0.684747928 0.5123716 -1.786143599 -1.16657451 FBgn0000712 flz filzig http://flybase.org/reports/FBgn0000712 - gene - - - flz - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal" "denticle belt,trichome,mouth hooks,denticle,microchaeta,cephalopharyngeal skeleton" FBgn0065987 iab-3-2.s iab-3-2.s http://flybase.org/reports/FBgn0065987 gene - - - "3-2 s, iab-3-2.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046841 ird27 immune response deficient 27 http://flybase.org/reports/FBgn0046841 gene molecular_function ; GO:0003674 | no biological data available humoral immune response ; GO:0006959 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ird27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,immune response defective,melanotic mass phenotype" melanotic mass FBgn0265722 CR44529 - http://flybase.org/reports/FBgn0265722 non_protein_coding_gene - - - "incRNA.431, CR44529, lincRNA.431" - CR44529 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030990 CG7556 - http://flybase.org/reports/FBgn0030990 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 - endomembrane system ; GO:0012505 | inferred from direct assay CG7556 "IPR001005:SANT/Myb domain, IPR001623:DnaJ domain, IPR009057:Homeobox domain-like, IPR018253:DnaJ domain, conserved site, IPR017877:Myb-like domain, IPR017884:SANT domain" CG7556 11-Aug-17 DroID_v2017_08 "Drer\dnajc4, Drer\dnajc7, Drer\dnajc1" "Scer\DJP1, Scer\JJJ2, Scer\ZUO1, Scer\XDJ1, Scer\ERJ5, Scer\MDJ1" "Cele\dnj-16, Cele\dnj-17, Cele\F54F2.9, Cele\dnj-18" "Xtro\dnajc1, Xtro\dnajc2" "Mmus\Dnajc7, Mmus\4930503B20Rik, Mmus\Dnajc1, Mmus\Dnajc18, Mmus\Dnajc4" "Hsap\DNAJC7, Hsap\DNAJC1, Hsap\DNAJC4, Hsap\DNAJC18" viable DRSC20052 IE 1.196139461 4.589133366 1.110456873 -2.87731758 -0.160399198 -0.467875709 FBgn0000797 fs(1)de8 female sterile (1) defective eggs 8 http://flybase.org/reports/FBgn0000797 - gene - - - "de8, fs(1)de8" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "dorsal appendage,chorion" FBgn0053303 CG33303 - http://flybase.org/reports/FBgn0053303 protein_coding_gene dolichyl-diphosphooligosaccharide-protein glycotransferase activity ; GO:0004579 | inferred from biological aspect of ancestor with PANTHER:PTN000471615 protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from biological aspect of ancestor with PANTHER:PTN000471615 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007676 oligosaccharyltransferase complex ; GO:0008250 | inferred from biological aspect of ancestor with PANTHER:PTN000471615 endomembrane system ; GO:0012505 | inferred from direct assay "CG5364, CG33303, OST" IPR007676:Ribophorin I CG33303 11-Aug-17 DroID_v2017_08 Drer\rpn1 Scer\OST1 Cele\ribo-1 Xtro\rpn1 Mmus\Rpn1 Hsap\RPN1 FBgn0028913 CG3473 - http://flybase.org/reports/FBgn0028913 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12492 postreplication repair ; GO:0006301 | inferred from biological aspect of ancestor with PANTHER:PTN000630262 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:12492 protein K63-linked ubiquitination ; GO:0070534 | inferred from biological aspect of ancestor with PANTHER:PTN000630262 ubiquitin ligase complex ; GO:0000151 | inferred from sequence or structural similarity with HGNC:12492 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000630262 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "BG:DS01486.1, BcDNA:AT16033, CG3473, cg3473" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG3473 11-Aug-17 DroID_v2017_08 "Drer\ube2d3, Drer\ube2e1, Drer\ube2d2, Drer\ube2nb, Drer\ube2e3, Drer\ube2t, Drer\ube2e2, Drer\ube2d1a, Drer\ube2na, Drer\ube2d1b, Drer\ube2d4" "Scer\UBC4, Scer\UBC5, Scer\PEX4, Scer\UBC13" "Cele\uev-3, Cele\ubc-13" "Xtro\ube2n, Xtro\ube2d3, Xtro\ube2e1, Xtro\ube2e3, Xtro\ube2d4, Xtro\ube2e2, Xtro\ube2d1" "Mmus\Ube2n, Mmus\Ube2dnl2, Mmus\Ube2t, Mmus\Ube2d1, Mmus\Ube2e3, Mmus\Ube2d2b, Mmus\Ube2e1, Mmus\Ube2e2, Mmus\Ube2d3, Mmus\Ube2dnl1, Mmus\Ube2z" "Hsap\UBE2T, Hsap\UBE2D3, Hsap\UBE2E1, Hsap\UBE2E3, Hsap\UBE2NL, Hsap\UBE2E2, Hsap\UBE2N, Hsap\UBE2D1, Hsap\UBE2D4, Hsap\UBE2D2, Hsap\UBE2Z" viable FBgn0061122 l(3)S004209a lethal (3) S004209a http://flybase.org/reports/FBgn0061122 gene - - - "0042/09, l(3)S004209a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065534 l(2)SH1091 lethal (2) SH1091 http://flybase.org/reports/FBgn0065534 gene - - - "l(2)SH1091, l(2)SH2 1091" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002387 l(3)93Dc lethal (3) 93Dc http://flybase.org/reports/FBgn0002387 - gene - - - "er11, l(3)er11, l(3)93Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" wing FBgn0000371 crib cribble http://flybase.org/reports/FBgn0000371 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available crib - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0065316 l(2)SH1927 lethal (2) SH1927 http://flybase.net/reports/FBgn0065316.html gene l(2)SH2 1927 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0032339 Wdr59 WD repeat domain 59 http://flybase.org/reports/FBgn0032339 protein_coding_gene - positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype Seh1-associated complex ; GO:0035859 | inferred from direct assay GATOR2 complex ; GO:0061700 | traceable author statement Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000002535 "CG4705, SEA3, FBtr0080196, Wdr59, Sea3" "IPR001680:WD40 repeat, IPR006575:RWD domain, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like" CG4705 11-Aug-17 DroID_v2017_08 Drer\wdr59 Scer\MTC5 - Xtro\wdr59 Mmus\Wdr59 Hsap\WDR59 viable FBgn0004698 Xpc "Xeroderma pigmentosum, complementation group C" http://flybase.org/reports/FBgn0004698 "FBgn0002896, FBgn0002898, FBgn0010427" protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from sequence or structural similarity with SGD:S000000964 damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000253194 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000253194 nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity with SGD:S000000964 nucleotide-excision repair ; GO:0006289 | inferred from biological aspect of ancestor with PANTHER:PTN000253194 meiotic mismatch repair involved in reciprocal meiotic recombination ; GO:0010777 | inferred from genetic interaction with Msh6 nucleotide-excision repair factor 2 complex ; GO:0000111 | inferred from biological aspect of ancestor with PANTHER:PTN000253194 cytosol ; GO:0005829 | inferred from sequence or structural similarity with SGD:S000000964 XPC complex ; GO:0071942 | inferred from biological aspect of ancestor with PANTHER:PTN000253194 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000964 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000253194 "mus(2)201G1, DhXPC, DhR4, Xpcc, DmXPC, mus(2)201, XPC[DM], mus212, mus201[G1], mus(2)201[GI], CG8153, mus210, Mus 210, Mus210, Xpc" "IPR018026:DNA repair protein Rad4, subgroup, IPR018326:Rad4 beta-hairpin domain 1, IPR018327:Rad4 beta-hairpin domain 2, IPR018328:Rad4 beta-hairpin domain 3, IPR004583:DNA repair protein Rad4, IPR018325:Rad4/PNGase transglutaminase-like fold" CG8153 11-Aug-17 DroID_v2017_08 Drer\xpc "Scer\RAD4, Scer\RAD34" Cele\xpc-1 - Mmus\Xpc Hsap\XPC "viable,chemical sensitive,recessive,DNA repair defective,fertile,maternal effect" FBgn0011184 l(1)294-27 lethal (1) 294-27 http://flybase.org/reports/FBgn0011184 FBgn0010200 gene - - - "294-27, l(1)294-27" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028690 Rpn5 Regulatory particle non-ATPase 5 http://flybase.org/reports/FBgn0028690 protein_coding_gene molecular_function ; GO:0003674 | no biological data available proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000091582 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 "cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000091582 proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000091582 nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000091582 proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000002306 proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9557 inferred from direct assay" "p55, CG1100, Rpn5, RPN5, rpn5" "IPR000717:Proteasome component (PCI) domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG1100 11-Aug-17 DroID_v2017_08 Drer\psmd12 Scer\RPN5 Cele\rpn-5 Xtro\psmd12 Mmus\Psmd12 Hsap\PSMD12 "lethal,partially lethal - majority die" DRSC28279 IK -2.35352585 -2.796241163 -1.328969724 -0.174825084 1.224998235 1.89839424 FBgn0011180 l(1)291-95 lethal (1) 291-95 http://flybase.org/reports/FBgn0011180 FBgn0010199 gene - - - "291-95, l(1)291-95" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260474 CG30002 - http://flybase.org/reports/FBgn0260474 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG30002 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG30002 11-Aug-17 DroID_v2017_08 Drer\masp2 - Cele\svh-1 - - - viable FBgn0260337 GSd057 - http://flybase.org/reports/FBgn0260337 gene - - - GSd057 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve" FBgn0069324 X-157-3 X-157-3 http://flybase.org/reports/FBgn0069324 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-157-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "extended germ band embryo,germline clone,maternal effect" FBgn0014109 anon-73B anon-73B http://flybase.org/reports/FBgn0014109 - gene - - - "TU10, anon-73B" - - 11-Aug-17 DroID_v2017_08 - - - - - - " egg stage | unfertilized egg , adult stage , embryonic stage " unfertilized egg

FBgn0015448 l(1)9BDa lethal (1) 9BDa http://flybase.org/reports/FBgn0015448 - gene - - - l(1)9BDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive,visible" wing FBgn0030855 CG5800 - http://flybase.org/reports/FBgn0030855 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD:S000003570 neurogenesis ; GO:0022008 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "DmRH14, cg5800, CG5800" "IPR025313:Domain of unknown function DUF4217, IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG5800 11-Aug-17 DroID_v2017_08 "Drer\ddx10, Drer\ddx18" "Scer\HAS1, Scer\MSS116, Scer\MRH4, Scer\DBP6, Scer\HCA4, Scer\DBP7" "Cele\B0511.6, Cele\ZC317.1, Cele\ZK512.2, Cele\Y23H5B.6, Cele\mut-14, Cele\smut-1" "Xtro\ddx18, Xtro\ddx10" "Mmus\Kctd19, Mmus\Ddx10, Mmus\Ddx18" "Hsap\DDX18, Hsap\DDX10, Hsap\KCTD19" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval somatic muscle,embryonic/larval neuroblast,ganglion mother cell" FBgn0261985 Ptpmeg Protein tyrosine phosphatase Meg http://flybase.org/reports/FBgn0261985 protein_coding_gene cytoskeletal protein binding ; GO:0008092 | inferred from electronic annotation with InterPro:IPR012151 protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with SGD:S000002389 protein dephosphorylation ; GO:0006470 | non-traceable author statement peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from direct assay negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype inferred from genetic interaction with Ras85D inferred from genetic interaction with Egfr central complex development ; GO:0048036 | inferred from mutant phenotype thermosensory behavior ; GO:0040040 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern mushroom body development ; GO:0016319 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002389 axon extension involved in axon guidance ; GO:0048846 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002389 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000002389 "ptpmeg, scc, CG1228, dMEG1, MEG1, anon-WO0118547.211, Ptpmeg, PTP-meg, Meg, ptmpeg, dPtpmeg, PTPMEG, dptpmeg" "IPR029021:Protein-tyrosine phosphatase-like, IPR029071:Ubiquitin-related domain, IPR000242:PTP type protein phosphatase, IPR000299:FERM domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR001478:PDZ domain, IPR011993:PH domain-like, IPR012151:Protein-tyrosine phosphatase, non-receptor type-3, -4, IPR014847:FERM adjacent (FA), IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR016130:Protein-tyrosine phosphatase, active site, IPR018980:FERM, C-terminal PH-like domain, IPR019747:FERM conserved site, IPR019748:FERM central domain, IPR018979:FERM, N-terminal, IPR019749:Band 4.1 domain, IPR003595:Protein-tyrosine phosphatase, catalytic" CG1228 11-Aug-17 DroID_v2017_08 "Drer\ptpn4a, Drer\ptpn3, Drer\ptpn4b, Drer\LOC101885876" "Scer\PTP3, Scer\PTP2" "Cele\Y41D4A.5, Cele\ptp-1" "Xtro\ptpn4, Xtro\ptpn3" "Mmus\Ptpn4, Mmus\Ptpn3" "Hsap\PTPN3, Hsap\PTPN4" DRSC08684 E 0.525507356 0.652815625 1.366287425 -1.518372638 0.506570183 -0.256805308 FBgn0262807 CG43178 - http://flybase.org/reports/FBgn0262807 protein_coding_gene - - - "CG43178, MIP03715_ORF_2" - CG43178 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032470 CG5142 - http://flybase.org/reports/FBgn0032470 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence or structural similarity with UniProtKB:Q8I7G4 intraciliary transport ; GO:0042073 | inferred from sequence or structural similarity with UniProtKB:Q8I7G4 protein polyglutamylation ; GO:0018095 | inferred from sequence or structural similarity with UniProtKB:Q8I7G4 intraciliary transport ; GO:0042073 | inferred from biological aspect of ancestor with PANTHER:PTN000468090 cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:1926052 cilium ; GO:0005929 | inferred from sequence or structural similarity with UniProtKB:Q8I7G4 cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN000468090 intraciliary transport particle B ; GO:0030992 | inferred from biological aspect of ancestor with PANTHER:PTN000468090 axonemal microtubule ; GO:0005879 | inferred from sequence or structural similarity with UniProtKB:Q8I7G4 cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:1926052 "CG5142, TTC30" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR013105:Tetratricopeptide repeat 2" CG5142 11-Aug-17 DroID_v2017_08 Drer\flr - Cele\dyf-1 Xtro\ttc30a "Mmus\Ttc30b, Mmus\Ttc30a1, Mmus\Ttc30a2" "Hsap\TTC30B, Hsap\TTC30A" viable DRSC02818 E 1.006394616 0.731902914 0.121282927 2.099690979 -0.296071661 0.167314647 FBgn0002588 M(1)13A Minute (1) 13A http://flybase.org/reports/FBgn0002588 - gene - - - M(1)13A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030290 CG11756 - http://flybase.org/reports/FBgn0030290 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT06648, CG11756" - CG11756 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0005140 l(2)B lethal (2) B http://flybase.org/reports/FBgn0005140 - gene - - - l(2)B - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014166 fs(1)18Da fs(1)18Da http://flybase.org/reports/FBgn0014166 - gene - - - fs(1)18Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,follicle cell" FBgn0064141 sl(2)AG2 sl(2)AG2 http://flybase.org/reports/FBgn0064141 gene - - - sl(2)AG2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0001775 l(1)M53 lethal (1) M53 http://flybase.org/reports/FBgn0001775 - gene - - - l(1)M53 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0034622 CG15666 - http://flybase.org/reports/FBgn0034622 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000470005 cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with MGI:MGI:2442833 BBSome ; GO:0034464 | inferred from sequence or structural similarity with MGI:MGI:2442833 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000470005 BBSome ; GO:0034464 | inferred from biological aspect of ancestor with PANTHER:PTN000470005 "CG15666, BcDNA:RH67628, BBS9" "IPR028074:PTHB1, C-terminal domain, IPR028073:PTHB1, N-terminal domain, IPR026511:Parathyroid hormone-responsive B1" CG15666 11-Aug-17 DroID_v2017_08 Drer\bbs9 - Cele\bbs-9 Xtro\bbs9 Mmus\Bbs9 Hsap\BBS9 viable FBgn0038766 CG4854 - http://flybase.org/reports/FBgn0038766 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG4854 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4854 11-Aug-17 DroID_v2017_08 "Drer\znf995, Drer\si:dkey-1b17.8, Drer\si:dkey-253d23.8, Drer\zgc:113030, Drer\LOC103908714, Drer\LOC100534908, Drer\zgc:113343, Drer\zgc:153116, Drer\si:dkeyp-53d3.3, Drer\LOC101884416, Drer\LOC798256, Drer\LOC100537687, Drer\znf1157, Drer\zgc:162936, Drer\zgc:113295, Drer\si:ch211-110e21.4, Drer\znf1161, Drer\si:ch1073-127d16.1, Drer\si:ch211-241e1.5, Drer\LOC100001832, Drer\znf1178, Drer\si:ch211-161m3.2, Drer\si:ch73-138e16.4, Drer\zgc:113294, Drer\LOC100535934, Drer\si:ch211-161m3.4, Drer\LOC100333228, Drer\si:ch211-202h22.10, Drer\znf1154, Drer\zgc:171551, Drer\si:ch73-299h12.6, Drer\si:ch73-367f21.6, Drer\LOC101886221, Drer\si:dkey-15h8.16, Drer\si:ch73-299h12.4, Drer\zgc:110249, Drer\LOC101884439, Drer\si:dkey-210j14.3, Drer\zgc:113377, Drer\znf970, Drer\zgc:163077, Drer\si:dkey-226l10.6, Drer\si:ch73-367f21.4, Drer\LOC100535458, Drer\zgc:171220, Drer\LOC100537377, Drer\LOC103910593, Drer\zgc:113348, Drer\si:rp71-1h20.5, Drer\zgc:175107, Drer\zgc:174288, Drer\LOC100002469, Drer\znf971, Drer\zgc:174263, Drer\si:ch211-222k6.1, Drer\klf1, Drer\blf, Drer\LOC101883936, Drer\LOC101885996" Scer\AZF1 "Cele\M03D4.4, Cele\klf-3, Cele\Y53H1A.2, Cele\pag-3, Cele\ztf-3, Cele\pat-9, Cele\klu-1, Cele\blmp-1" Xtro\osr2 "Mmus\Zfp810, Mmus\Gm13212, Mmus\Zfp771, Mmus\Zfp62, Mmus\Zfp708, Mmus\Zfp787, Mmus\Zfp984, Mmus\Zfp93, Mmus\Zscan2, Mmus\Zfp12, Mmus\Zfp239, Mmus\Zfp422" "Hsap\RBAK-RBAKDN, Hsap\ZNF792, Hsap\ZNF394, Hsap\ZNF560, Hsap\ZNF681, Hsap\ZNF761, Hsap\ZNF480, Hsap\ZNF492, Hsap\ZFP28, Hsap\ZNF816, Hsap\ZNF845, Hsap\ZNF485, Hsap\ZNF570, Hsap\ZNF211, Hsap\ZNF595, Hsap\ZNF558, Hsap\ZNF98, Hsap\ZNF891, Hsap\ZNF107, Hsap\ZNF850, Hsap\ZNF764, Hsap\ZSCAN2, Hsap\ZNF527, Hsap\ZSCAN29, Hsap\ZNF730, Hsap\ZNF233, Hsap\ZNF707, Hsap\ZSCAN30, Hsap\ZNF22, Hsap\ZSCAN32, Hsap\ZNF679, Hsap\ZNF793, Hsap\ZNF28, Hsap\ZNF117, Hsap\ZNF468, Hsap\ZNF785, Hsap\ZNF766, Hsap\ZNF623, Hsap\ZNF43, Hsap\ZNF610, Hsap\ZNF568, Hsap\ZNF675, Hsap\ZNF721" "viable,fertile" FBgn0284245 eEF1alpha1 eukaryotic translation elongation factor 1 alpha 1 http://flybase.org/reports/FBgn0284245 protein_coding_gene "translation elongation factor activity ; GO:0003746 | inferred from electronic annotation with InterPro:IPR004539 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR004539 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity" translational elongation ; GO:0006414 | inferred from electronic annotation with InterPro:IPR004539 translational elongation ; GO:0006414 | inferred from sequence or structural similarity determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004539 lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity eukaryotic translation elongation factor 1 complex ; GO:0005853 | inferred from sequence or structural similarity "Ef1alpha48D, l(2)00248, EF1A1, CG8280, Ef1alpha 48D, ef-1alpha, EF1alpha48D, Ef1alpha48E, EF, EF-1alpha, EF1alpha, eEF1alpha, EF-1alphaF1, Dm0084, l(2)1275, EF1-alpha, clone 2.46, clone 1.17, EF-1alphaF, EF-1alphaF[[1]], 1275, Ef1a10, EF-1[a], EF-1, EF-1alpha F1, F1 EF-1alpha, l(2)k07303, EF-1a, F1, DmEF1, l(2)01275, anon-EST:Liang-2.46, anon-EST:Liang-1.17, Ef1alpha1, Efalpha48D, Ef1a48D, EF1alpha 48D, EF11_DROME, Ef1, chr2R:7409490..7409690, chr2R:7410009..7410129, l(2)248, 0248, eEF1alpha1" "IPR000795:Transcription factor, GTP-binding domain, IPR004160:Translation elongation factor EFTu/EF1A, C-terminal, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR004539:Translation elongation factor EF1A, eukaryotic/archaeal, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031157:Tr-type G domain, conserved site" CG8280 11-Aug-17 DroID_v2017_08 "Drer\eef1a1a, Drer\eef1a2, Drer\eef1a1b, Drer\eef1a1l1, Drer\eef1a1l2, Drer\si:dkey-37o8.1" "Scer\TEF1, Scer\TEF2" "Cele\eef-1A.2, Cele\eef-1A.1" "Xtro\42Sp50, Xtro\eef1a1, Xtro\eef1a1o, Xtro\eef1a2, Xtro\LOC101734345" "Mmus\Eef1a1, Mmus\Eef1a2" "Hsap\EEF1A2, Hsap\EEF1A1" "lethal,recessive" FBgn0016645 ER3-3 ER3-3 http://flybase.org/reports/FBgn0016645 - gene - - - ER3-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031702 fusl fuseless http://flybase.org/reports/FBgn0031702 protein_coding_gene - clustering of voltage-gated calcium channels ; GO:0070073 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype presynaptic membrane ; GO:0042734 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay "fusl, CG14021" IPR032751:Protein fuseless CG14021 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,locomotor behavior defective,viable" "retina,embryonic/larval neuromuscular junction,synaptic vesicle" FBgn0028136 l(3)S049405a lethal (3) S049405a http://flybase.org/reports/FBgn0028136 gene - - - "0494/05, l(3)S049405, l(3)S049405a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0060601 l(3)S091801b lethal (3) S091801b http://flybase.org/reports/FBgn0060601 gene - - - "0918/01, l(3)S091801b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0022959 yps ypsilon schachtel http://flybase.org/reports/FBgn0022959 - protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002059 mRNA binding ; GO:0003729 | traceable author statement "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002059 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 oogenesis ; GO:0048477 | non-traceable author statement" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG5654, Yps, p57, p45, YPS, yps" "IPR002059:Cold-shock protein, DNA-binding, IPR011129:Cold shock domain, IPR012340:Nucleic acid-binding, OB-fold, IPR019844:Cold-shock conserved site" CG5654 11-Aug-17 DroID_v2017_08 "Drer\lin28a, Drer\si:ch1073-284b18.2, Drer\csdc2a, Drer\ybx1" - "Cele\cey-3, Cele\cey-4, Cele\cey-2, Cele\cey-1, Cele\lin-28" "Xtro\lin28b, Xtro\carhsp1, Xtro\ybx1, Xtro\lin28a, Xtro\ybx3, Xtro\ybx2" "Mmus\Ybx3, Mmus\Csdc2, Mmus\Ybx2, Mmus\Carhsp1, Mmus\Ybx1, Mmus\Lin28b, Mmus\Lin28a" "Hsap\YBX2, Hsap\LIN28B, Hsap\CSDC2, Hsap\YBX1, Hsap\CARHSP1, Hsap\LIN28A, Hsap\YBX3" "lethal,viable,female fertile,fertile" FBgn0029816 CG12729 - http://flybase.org/reports/FBgn0029816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12729 "IPR021625:PI31 proteasome regulator, N-terminal" CG12729 11-Aug-17 DroID_v2017_08 Drer\psmf1 - - - Mmus\Psmf1 Hsap\PSMF1 "partially lethal - majority die,some die during pupal stage" FBgn0038891 CG15499 - http://flybase.org/reports/FBgn0038891 protein_coding_gene - - - "CG15499, CR43372" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023220 E(lz)174 E(lz)174 http://flybase.org/reports/FBgn0023220 - gene - - - E(lz)174 - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0015456 l(2)37CDa lethal (2) 37CDa http://flybase.org/reports/FBgn0015456 - gene - - - "l(2)E142,M, l(2)37CDa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259462 EP-469.1 - http://flybase.org/reports/FBgn0259462 gene - - - EP-469.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0069217 gl(3R)66-35 gl(3R)66-35 http://flybase.org/reports/FBgn0069217 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(3R)66-35 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "dorsal appendage,germline clone,maternal effect,embryonic head,embryonic segment" FBgn0011796 l(3)j7A6 lethal (3) j7A6 http://flybase.org/reports/FBgn0011796 - gene - - - "l(3)j7A6, l(3j7A6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030748 Traf-like TNF-receptor-associated factor-like http://flybase.org/reports/FBgn0030748 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from electronic annotation with InterPro:IPR027139 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9U6M0 protein ubiquitination ; GO:0016567 | inferred from electronic annotation with InterPro:IPR027139 immune response ; GO:0006955 | inferred from electronic annotation with InterPro:IPR027139 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR027139 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with Traf4 "TRAF3, dTRAF3, CG4394, Traf-like, Traf3, Traf-related" "IPR002083:MATH/TRAF domain, IPR008974:TRAF-like, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027139:TNF receptor-associated factor 6" CG4394 11-Aug-17 DroID_v2017_08 "Drer\traf2a, Drer\LOC100005446, Drer\traf5, Drer\traf6, Drer\traf2b, Drer\traf1, Drer\traf3" - "Cele\trf-1, Cele\F57B10.4, Cele\Y22D7AR.2, Cele\Y110A7A.2" "Xtro\traf5, Xtro\traf2, Xtro\traf3, Xtro\traf6" "Mmus\Traf1, Mmus\Traf5, Mmus\Traf2, Mmus\Traf6, Mmus\Traf3" "Hsap\ERC1, Hsap\TRAF5, Hsap\TRAF1, Hsap\TRAF3, Hsap\TRAF6, Hsap\TRAF2" viable FBgn0040225 en::osa en::osa http://flybase.org/reports/FBgn0040225 engineered_fusion_gene - - - en::osa - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "macrochaeta,ectopic,microchaeta,wing margin bristle,wing vein" FBgn0039126 CG13601 - http://flybase.org/reports/FBgn0039126 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of lipid metabolic process ; GO:0019216 | inferred from biological aspect of ancestor with PANTHER:PTN000281649 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000281649 CG13601 IPR010754:Optic atrophy 3-like CG13601 11-Aug-17 DroID_v2017_08 Drer\opa3 - Cele\H43I07.1 Xtro\opa3 Mmus\Opa3 Hsap\OPA3 viable DRSC14604 IE 1.580760816 0.087020579 3.374129783 0.263582245 0.748009906 -0.599075529 FBgn0260116 2L4155 - http://flybase.org/reports/FBgn0260116 gene - - - 2L4155 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0027177 l(2)60Ag lethal (2) 60Ag http://flybase.org/reports/FBgn0027177 - gene - - - l(2)60Ag - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267523 5.8SrRNA-Psi:CR45863 5.8S ribosomal RNA pseudogene:CR45863 http://flybase.org/reports/FBgn0267523 pseudogene_attribute - - - "5.8SrRNA-Psi:CR45863, CR45863" - CR45863 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082616 S(CycE[JP])E9S1 S(CycE[JP])E9S1 http://flybase.org/reports/FBgn0082616 gene - - - "E9S1, S(CycE[JP])E9S1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0031356 CG17660 - http://flybase.org/reports/FBgn0031356 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009637 CG17660 IPR009637:Lung seven transmembrane receptor-like CG17660 11-Aug-17 DroID_v2017_08 "Drer\zgc:162698, Drer\tmem87b" "Scer\PTM1, Scer\YHL017W" Cele\C52B9.4 "Xtro\tmem87a, Xtro\tmem87b" "Mmus\Tmem87b, Mmus\Tmem87a" "Hsap\TMEM87B, Hsap\TMEM87A" viable FBgn0000770 fs(1)A1074 female sterile (1) A1074 http://flybase.org/reports/FBgn0000770 - gene - - - fs(1)A1074 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,rescuable maternal effect,heat sensitive,female sterile,recessive" FBgn0267922 CR46203 - http://flybase.org/reports/FBgn0267922 non_protein_coding_gene - - - "CR46203, lincRNA.756" - CR46203 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039530 Tusp Tusp http://flybase.org/reports/FBgn0039530 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000421275 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001496 protein localization to cilium ; GO:0061512 | inferred from biological aspect of ancestor with PANTHER:PTN000421275 cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN000421275 "TUSP, CG5586, Tusp, DMG2-MB6.chr3R.24.043" "IPR025659:Tubby C-terminal-like domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000007:Tubby, C-terminal, IPR001496:SOCS box domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain" CG5586 11-Aug-17 DroID_v2017_08 "Drer\tulp4a, Drer\tulp4b" - Cele\tub-2 - Mmus\Tulp4 Hsap\TULP4 viable FBgn0027198 l(2)2B lethal (2) 2B http://flybase.org/reports/FBgn0027198 - gene - - - l(2)2B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027114 mei-P38 mei-P38 http://flybase.org/reports/FBgn0027114 - gene - - - mei-P38 - - 11-Aug-17 DroID_v2017_08 - - - - - - meiotic cell cycle defective FBgn0267976 Tim23 Translocase of inner mitochondrial membrane 23 http://flybase.org/reports/FBgn0267976 protein_coding_gene protein channel activity ; GO:0015266 | inferred from biological aspect of ancestor with PANTHER:PTN000394914 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000394914 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000394914 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000394914 "Tim23, CG40042, LP07554, BEST:GH02609, BcDNA:SD19278" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG40042 11-Aug-17 DroID_v2017_08 "Drer\timm23a, Drer\timm23b" Scer\TIM23 Cele\timm-23 Xtro\timm23 Mmus\Timm23 "Hsap\TIMM23B, Hsap\TIMM23" FBgn0024928 Su(var)2-b701 Su(var)2-b701 http://flybase.org/reports/FBgn0024928 - gene - - - "Su-var(2)b701, Su(var)2-b701" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044513 l(3)80Fe lethal (3) 80Fe http://flybase.org/reports/FBgn0044513 gene - - - "l5A, l(3)Lh5, l(3)80Fe, 80Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0043783 CG32444 - http://flybase.org/reports/FBgn0043783 protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718 aldose 1-epimerase activity ; GO:0004034 | inferred from biological aspect of ancestor with PANTHER:PTN000009552" galactose catabolic process via UDP-galactose ; GO:0033499 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 glucose metabolic process ; GO:0006006 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 - "CT3430, CG14576, BcDNA:GH08902, CG12562, CG32444, aldose 1-epi" "IPR008183:Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013:Galactose mutarotase-like domain, IPR014718:Glycoside hydrolase-type carbohydrate-binding, IPR015443:Aldose 1-epimerase" CG32444 11-Aug-17 DroID_v2017_08 "Drer\galm, Drer\mfng, Drer\rfng, Drer\lfng" "Scer\YHR210C, Scer\YNR071C, Scer\GAL10" "Cele\C01B4.6, Cele\Y19D10A.16" "Xtro\galm, Xtro\rfng, Xtro\lfng" "Mmus\Galm, Mmus\Lfng, Mmus\Rfng, Mmus\Mfng" "Hsap\RFNG, Hsap\GALM, Hsap\LFNG, Hsap\MFNG" "viable,fertile" FBgn0266877 CR45338 - http://flybase.org/reports/FBgn0266877 non_protein_coding_gene - - - CR45338 - CR45338 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264369 CR43821 - http://flybase.org/reports/FBgn0264369 non_protein_coding_gene - - - CR43821 - CR43821 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003303 rv raven http://flybase.org/reports/FBgn0003303 - gene - - - rv - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,female sterile,viable,male,reduced,male fertile,female,poor,eye color defective" "pigment cell,wing" FBgn0265087 CR44198 - http://flybase.org/reports/FBgn0265087 non_protein_coding_gene - - - "CR44198, lincRNA.126" - CR44198 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065886 l(2)SH0227 lethal (2) SH0227 http://flybase.org/reports/FBgn0065886 gene - - - "l(2)SH0227, l(2)SH2 0227" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022759 Wmc3 Wee-Mik-Complementing 3 http://flybase.org/reports/FBgn0022759 - gene - - - "WMC3, Wmc3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029173 fu2 fu2 http://flybase.org/reports/FBgn0029173 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "FU12, CG9233, fu2" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG9233 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-127d16.1, Drer\zgc:113343, Drer\zgc:171220, Drer\LOC100535458, Drer\LOC100001832, Drer\zgc:110249, Drer\si:ch211-202h22.10, Drer\LOC101884439, Drer\LOC103908714, Drer\si:ch211-241e1.5, Drer\si:dkey-1b17.8, Drer\zgc:113348, Drer\LOC100535934, Drer\znf970, Drer\zgc:174263, Drer\znf1161, Drer\znf1154, Drer\si:ch211-161m3.4, Drer\si:ch73-367f21.4, Drer\LOC100537687, Drer\LOC101885996, Drer\si:ch73-138e16.4, Drer\zgc:163077, Drer\znf1157, Drer\blf, Drer\zgc:174288, Drer\si:dkey-210j14.3, Drer\si:ch211-110e21.4, Drer\si:ch73-367f21.6, Drer\zgc:153116, Drer\klf1, Drer\LOC101883936, Drer\si:ch73-299h12.4, Drer\zgc:175107, Drer\si:ch211-222k6.1, Drer\znf1178, Drer\LOC100330321, Drer\LOC100333228, Drer\zgc:171551, Drer\si:dkey-226l10.6, Drer\LOC101886221, Drer\LOC101884416, Drer\zgc:113030, Drer\LOC100537377, Drer\zgc:113295, Drer\si:ch73-299h12.6, Drer\LOC103910593, Drer\si:rp71-1h20.5, Drer\si:dkeyp-53d3.3, Drer\LOC798256, Drer\si:dkey-253d23.8, Drer\znf995, Drer\zgc:113377, Drer\zgc:113294, Drer\znf971, Drer\LOC100002469, Drer\si:ch211-161m3.2, Drer\LOC100534908, Drer\si:dkey-15h8.16, Drer\zgc:162936" Scer\AZF1 "Cele\zfp-2, Cele\eor-1, Cele\blmp-1, Cele\fezf-1, Cele\C04F5.9, Cele\Y55F3AM.14" Xtro\znf250 "Mmus\Zfp786, Mmus\Zfp771, Mmus\Zfp799, Mmus\Zfp422" "Hsap\ZNF786, Hsap\ZNF514, Hsap\ZNF610, Hsap\ZNF22, Hsap\ZNF260" "decreased cell death,recessive,somatic clone,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0024233 aos::spi argos::spi http://flybase.org/reports/FBgn0024233 - engineered_fusion_gene - - - "gil::spi, argos::spi, aos::spi" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,cone cell,pigment cell,wing vein" FBgn0036668 Zcchc7 Zinc finger CCHC-type containing 7 http://flybase.org/reports/FBgn0036668 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 defense response to virus ; GO:0051607 | inferred from mutant phenotype - "CG9715, Zcchc7, dZcchc7" "IPR001878:Zinc finger, CCHC-type" CG9715 11-Aug-17 DroID_v2017_08 "Drer\zcchc14, Drer\cnbpb, Drer\zcchc7, Drer\zcchc9, Drer\cnbpa" "Scer\GIS2, Scer\AIR2, Scer\AIR1" Cele\K08D12.3 "Xtro\zcchc9, Xtro\zcchc7, Xtro\cnbp" "Mmus\Zcchc14, Mmus\Zcchc13, Mmus\Cnbp, Mmus\Zcchc9, Mmus\Zcchc7" "Hsap\ZCCHC13, Hsap\ZCCHC7, Hsap\CNBP, Hsap\ZCCHC9, Hsap\ZCCHC14" "viable,visible,body color defective" mesothoracic tergum DRSC11099 E 0.349579035 0.994289176 3.475520397 -0.502611674 -0.179284216 0.402684993 FBgn0265701 CR44508 - http://flybase.org/reports/FBgn0265701 non_protein_coding_gene - - - "lincRNA.966, CR44508" - CR44508 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051100 CG31100 - http://flybase.org/reports/FBgn0051100 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "CG11978, CG11976, CG31100" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG31100 11-Aug-17 DroID_v2017_08 "Drer\slc2a12, Drer\slc2a6, Drer\slc2a13b, Drer\LOC101882338, Drer\slc2a10, Drer\slc2a8" "Scer\HXT8, Scer\YDL199C, Scer\HXT16, Scer\ITR2, Scer\MPH2, Scer\HXT13, Scer\HXT3, Scer\HXT1, Scer\HXT10, Scer\ITR1, Scer\VBA1, Scer\SNF3, Scer\HXT15, Scer\GEX1, Scer\MAL31, Scer\MPH3, Scer\AZR1, Scer\ATR1, Scer\SGE1, Scer\YDR387C, Scer\MAL11, Scer\VBA3, Scer\HXT7, Scer\YFL040W, Scer\HXT9, Scer\HXT6, Scer\HXT14, Scer\ENB1, Scer\VBA4, Scer\VBA5, Scer\HXT4, Scer\HXT11, Scer\HXT2, Scer\RGT2, Scer\VBA2, Scer\STL1, Scer\GAL2, Scer\HXT5, Scer\GEX2, Scer\YMR279C, Scer\HXT17" - "Xtro\slc2a10, Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a12" "Mmus\Slc2a13, Mmus\Slc2a8, Mmus\Slc2a6, Mmus\Slc2a12, Mmus\Slc2a10" "Hsap\SLC2A13, Hsap\SLC2A6, Hsap\SLC2A8, Hsap\SLC2A12, Hsap\SLC2A10" "viable,fertile" FBgn0265591 CR44418 - http://flybase.org/reports/FBgn0265591 non_protein_coding_gene - - - CR44418 - CR44418 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035343 CG16762 - http://flybase.org/reports/FBgn0035343 protein_coding_gene - - - CG16762 IPR007931:Protein of unknown function DUF725 CG16762 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0005401 l(1)10Aj lethal (1) 10Aj http://flybase.org/reports/FBgn0005401 - gene - - - l(1)10Aj - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0014062 Su(tor)3-1 Su(tor)3-1 http://flybase.org/reports/FBgn0014062 - gene - - - Su(tor)3-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0267155 CR45595 - http://flybase.org/reports/FBgn0267155 non_protein_coding_gene - - - CR45595 - CR45595 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032783 CG10237 - http://flybase.org/reports/FBgn0032783 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 CG10237 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG10237 11-Aug-17 DroID_v2017_08 "Drer\ttpal, Drer\ttpa, Drer\rlbp1a, Drer\clvs2, Drer\sec14l8, Drer\rlbp1b, Drer\sec14l7" "Scer\SFH5, Scer\SEC14, Scer\YKL091C, Scer\PDR16" - "Xtro\sec14l5, Xtro\sec14l3, Xtro\ttpal, Xtro\sec14l1, Xtro\clvs1, Xtro\mospd2, Xtro\ttpa, Xtro\clvs2, Xtro\rlbp1" "Mmus\Ttpa, Mmus\Sec14l4, Mmus\Sec14l3, Mmus\Rlbp1, Mmus\Sec14l1, Mmus\Sec14l2, Mmus\Clvs1, Mmus\Clvs2, Mmus\Ttpal, Mmus\Sec14l5" "Hsap\SEC14L4, Hsap\SEC14L3, Hsap\SEC14L6, Hsap\SEC14L2, Hsap\TTPAL, Hsap\SEC14L5, Hsap\CLVS1, Hsap\CLVS2, Hsap\RLBP1, Hsap\SEC14L1, Hsap\TTPA" FBgn0000319 Chc Clathrin heavy chain http://flybase.org/reports/FBgn0000319 "FBgn0014972, FBgn0028268" protein_coding_gene "structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR001473, InterPro:IPR015348, InterPro:IPR016025 protein binding ; GO:0005515 | inferred from physical interaction with BicD clathrin light chain binding ; GO:0032051 | inferred from sequence or structural similarity with HGNC:2090" "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR000547, InterPro:IPR001473, InterPro:IPR015348, InterPro:IPR016025 liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype regulation of growth ; GO:0040008 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype puparial adhesion ; GO:0007594 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype secretory granule organization ; GO:0033363 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype synaptic vesicle coating ; GO:0016183 | traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype" "clathrin coat of coated pit ; GO:0030132 | inferred from electronic annotation with InterPro:IPR001473, InterPro:IPR015348, InterPro:IPR016025 clathrin coat of trans-Golgi network vesicle ; GO:0030130 | inferred from electronic annotation with InterPro:IPR001473, InterPro:IPR015348, InterPro:IPR016025 lipid particle ; GO:0005811 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from direct assay secretory granule ; GO:0030141 | inferred from direct assay clathrin complex ; GO:0071439 | inferred from sequence or structural similarity with HGNC:2090 plasma membrane ; GO:0005886 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay clathrin-coated vesicle ; GO:0030136 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay synaptic vesicle ; GO:0008021 | traceable author statement coated vesicle ; GO:0030135 | traceable author statement clathrin-coated pit ; GO:0005905 | traceable author statement clathrin-coated pit ; GO:0005905 | inferred from direct assay clathrin vesicle coat ; GO:0030125 | traceable author statement" "chc, CHC, CG9012, D-Chc, CLH, l(1)VI, l(1)G0438, l(1)13Fb, Chc, dCHC, Cla, Clh, chc1" "IPR000547:Clathrin, heavy chain/VPS, 7-fold repeat, IPR001473:Clathrin, heavy chain, propeller, N-terminal, IPR011990:Tetratricopeptide-like helical domain, IPR015348:Clathrin, heavy chain, linker, core motif, IPR016024:Armadillo-type fold, IPR016341:Clathrin, heavy chain, IPR012331:Clathrin, heavy chain, linker, IPR022365:Clathrin, heavy chain, propeller repeat" CG9012 11-Aug-17 DroID_v2017_08 "Drer\cltcl1, Drer\cltca, Drer\cltcb" Scer\CHC1 Cele\chc-1 Xtro\cltc "Mmus\Cltc, Mmus\Clhc1" "Hsap\CLHC1, Hsap\CLTC, Hsap\CLTCL1" adult stage "viable,neurophysiology defective,chemical conditional,lethal,recessive,increased cell death,wild-type,cell lethal,cell autonomous,germline clone,neoplasia,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during larval stage,lethal - all die before end of pupal stage,polyphasic,partially lethal - majority die,male sterile,female semi-sterile,partially,heat sensitive,neuroanatomy defective" "eye disc,secondary pigment cell,tertiary pigment cell,egg chamber,germline clone,presumptive embryonic/larval tracheal system,embryonic/larval dorsal trunk,spermatozoon,primary spermatocyte cyst,major mitochondrial derivative,minor mitochondrial derivative,spermatid & nucleus,microtubule,oocyte,interommatidial bristle,embryonic/larval garland cell,synaptic vesicleAppl.G1a,synapseAppl.G1a,bouton,embryonic/larval salivary gland | third instar larval stage,secretory granuleAB1,eye" DRSC20229 E 0.704200604 0.604525578 6.130681265 1.709516752 0.442769017 -0.050066709 FBgn0036181 Muc68Ca Mucin 68Ca http://flybase.org/reports/FBgn0036181 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model - extracellular matrix ; GO:0031012 | inferred from sequence model "Muc68Ca, CG18331, cg18331" - CG18331 11-Aug-17 DroID_v2017_08 "Drer\scospondin, Drer\asic2, Drer\otogl, Drer\LOC799643, Drer\vwf" "Scer\FLO1, Scer\FLO11, Scer\FLO9, Scer\HKR1, Scer\MSB2, Scer\FLO5, Scer\FLO10, Scer\FIG2, Scer\PRM7, Scer\YIL169C, Scer\YMR317W, Scer\HPF1" "Cele\H02F09.3, Cele\srap-1, Cele\dpy-6, Cele\clec-223, Cele\ZC178.2, Cele\H43E16.1" - "Mmus\Muc5ac, Mmus\Sspo, Mmus\Muc4, Mmus\Vwf, Mmus\Muc6, Mmus\Muc5b, Mmus\Muc2" "Hsap\SSPO, Hsap\MUC19, Hsap\MUC2, Hsap\MUC16, Hsap\MUC17, Hsap\VWF, Hsap\OTOG, Hsap\MUC5B, Hsap\MUC4, Hsap\MUC6" viable FBgn0263217 CR43387 - http://flybase.org/reports/FBgn0263217 non_protein_coding_gene - - - CR43387 - CR43387 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266396 CR45036 - http://flybase.org/reports/FBgn0266396 non_protein_coding_gene - - - CR45036 - CR45036 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266279 CR44964 - http://flybase.org/reports/FBgn0266279 non_protein_coding_gene - - - CR44964 - CR44964 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083908 DJ817 DJ817 http://flybase.org/reports/FBgn0083908 gene - - - DJ817 - - 11-Aug-17 DroID_v2017_08 - - - - - - long lived FBgn0038299 Spn88Eb Serpin 88Eb http://flybase.org/reports/FBgn0038299 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp response to fungus ; GO:0009620 | inferred from expression pattern sleep ; GO:0030431 | inferred from expression pattern negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "Spn88Eb, CG6687" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG6687 11-Aug-17 DroID_v2017_08 "Drer\serpinb1l3, Drer\serpinf2a, Drer\serpini1, Drer\agt, Drer\serpinb1l2, Drer\serpind1, Drer\zgc:173729, Drer\serpinf1, Drer\serpinf2b, Drer\serping1, Drer\serpinb1" - "Cele\C28G1.2, Cele\srp-7, Cele\srp-1, Cele\srp-2, Cele\srp-3, Cele\srp-8, Cele\srp-6" - "Mmus\Serpinb7, Mmus\Serpinb6a, Mmus\Serpini2, Mmus\Serpinb9d, Mmus\Serpini1, Mmus\Serpinc1, Mmus\Serpinb3a, Mmus\Agt, Mmus\Serpinb3c, Mmus\Serpinb1b, Mmus\Serpinb3b, Mmus\Serpinb1c, Mmus\Serpind1, Mmus\Serpinb1a, Mmus\Serpinb6b, Mmus\Serpinb6c, Mmus\Serpinb9c, Mmus\Serpinb3d, Mmus\Serpinf2, Mmus\Serpinf1" "Hsap\SERPINB7, Hsap\SERPINB6, Hsap\SERPIND1, Hsap\SERPINB3, Hsap\SERPINF2, Hsap\SERPINB4, Hsap\SERPINC1, Hsap\SERPINI2, Hsap\AGT, Hsap\SERPINI1, Hsap\SERPINF1, Hsap\SERPINB1" "viable,body color defective,fertile" mesothoracic tergum FBgn0261675 Npc1b Niemann-Pick type C-1b http://flybase.org/reports/FBgn0261675 protein_coding_gene - central nervous system development ; GO:0007417 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype intestinal cholesterol absorption ; GO:0030299 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR003392 "NPC1b, CG12092, Npc1b, dncp1b, npc1b, l(1)19Ec, l(1)2-3, R9-28, l(1)R-9-28, lt2-14a, lN5, R-9-28, AF2/19, 151, Q256, l152, l151, 7, 4" "IPR000731:Sterol-sensing domain, IPR003392:Protein patched/dispatched, IPR032190:Niemann-Pick C1, N-terminal" CG12092 11-Aug-17 DroID_v2017_08 "Drer\npc1l1, Drer\scap, Drer\npc1" Scer\NCR1 "Cele\ncr-2, Cele\ptr-22, Cele\ncr-1" "Xtro\npc1, Xtro\npc1l1, Xtro\scap" "Mmus\Npc1l1, Mmus\Npc1, Mmus\Scap" "Hsap\SCAP, Hsap\NPC1L1, Hsap\NPC1" FBgn0002197 l(3)67Aa lethal (3) 67Aa http://flybase.org/reports/FBgn0002197 - gene - - - l(3)67Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0033395 Cyp4p2 Cyp4p2 http://flybase.org/reports/FBgn0033395 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 sleep ; GO:0030431 | inferred from expression pattern" - "4p2, CG1944, Cyp4p2, CYP4P2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG1944 11-Aug-17 DroID_v2017_08 "Drer\cyp46a1.2, Drer\cyp2p10, Drer\cyp3c4, Drer\cyp19a1b, Drer\LOC100329425, Drer\cyp46a1.1, Drer\cyp3c1, Drer\cyp26c1, Drer\cyp4v8, Drer\cyp3a65, Drer\cyp4f3, Drer\cyp3c3, Drer\cyp3c2, Drer\cyp4t8, Drer\cyp4v7, Drer\cyp20a1, Drer\cyp46a1.4, Drer\cyp46a1.3, Drer\cyp19a1a, Drer\cyp26b1, Drer\cyp26a1" "Scer\DIT2, Scer\ERG5" "Cele\cyp-13A11, Cele\cyp-29A2, Cele\cyp-13A8, Cele\cyp-13A12, Cele\cyp-29A4, Cele\cyp-29A3, Cele\cyp-31A3, Cele\cyp-13A7, Cele\cyp-13A4, Cele\cyp-32B1, Cele\cyp-25A2, Cele\cyp-13A1, Cele\cyp-13A5, Cele\cyp-25A3, Cele\cyp-25A1, Cele\cyp-31A2, Cele\cyp-25A4, Cele\cyp-37B1, Cele\cyp-37A1, Cele\cyp-13A3, Cele\cyp-13A10, Cele\cyp-32A1, Cele\cyp-42A1" "Xtro\cyp4b1.2, Xtro\LOC100488227, Xtro\LOC100487918, Xtro\cyp19a1, Xtro\cyp26b1, Xtro\cyp4b1, Xtro\cyp4f2, Xtro\cyp4f22, Xtro\mgc108213, Xtro\cyp20a1, Xtro\cyp26c1, Xtro\cyp4v2, Xtro\cyp26a1" "Mmus\Cyp4f39, Mmus\Cyp3a25, Mmus\Cyp26b1, Mmus\Cyp4a14, Mmus\Cyp20a1, Mmus\Cyp4f40, Mmus\Cyp3a57, Mmus\Cyp4f18, Mmus\Cyp3a41a, Mmus\Cyp3a11, Mmus\Cyp4f15, Mmus\Cyp4a12b, Mmus\Cyp4a10, Mmus\Cyp4a31, Mmus\Cyp4a30b, Mmus\Cyp26c1, Mmus\Cyp4x1, Mmus\Cyp3a16, Mmus\Cyp3a13, Mmus\Cyp26a1, Mmus\Cyp46a1, Mmus\Cyp4a12a, Mmus\Cyp4f37, Mmus\Cyp4v3, Mmus\Cyp4a32, Mmus\Cyp4f13, Mmus\Cyp4f17, Mmus\Cyp4a29, Mmus\Cyp4b1, Mmus\Cyp3a59, Mmus\Cyp4f14, Mmus\Cyp19a1, Mmus\Cyp3a41b, Mmus\Cyp3a44, Mmus\Cyp4f16" "Hsap\CYP4F2, Hsap\CYP26A1, Hsap\CYP4F22, Hsap\CYP20A1, Hsap\CYP4X1, Hsap\CYP4F12, Hsap\CYP3A5, Hsap\CYP4A11, Hsap\CYP26C1, Hsap\CYP26B1, Hsap\CYP4F11, Hsap\CYP4F3, Hsap\CYP4A22, Hsap\CYP3A4, Hsap\CYP4V2, Hsap\CYP4B1, Hsap\CYP3A43, Hsap\CYP46A1, Hsap\CYP19A1, Hsap\CYP4Z1, Hsap\CYP3A7, Hsap\CYP4F8" viable FBgn0034166 CG6472 - http://flybase.org/reports/FBgn0034166 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available CG6472 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6472 11-Aug-17 DroID_v2017_08 "Drer\LOC101884800, Drer\lipca, Drer\lipib, Drer\LOC100331214, Drer\pla1a, Drer\lipia, Drer\lipg, Drer\lpl" - - "Xtro\pnliprp2, Xtro\lipc, Xtro\lipg, Xtro\lpl" "Mmus\Lipc, Mmus\Lpl, Mmus\Lipg, Mmus\Liph, Mmus\Pnliprp1, Mmus\Pnlip, Mmus\Lipi, Mmus\Pnliprp2, Mmus\Pla1a" "Hsap\LPL, Hsap\PNLIPRP2, Hsap\LIPI, Hsap\PNLIP, Hsap\LIPC, Hsap\LIPG, Hsap\PNLIPRP1, Hsap\PNLIPRP3, Hsap\PLA1A, Hsap\LIPH" viable FBgn0003718 tlc tender little chaetae http://flybase.org/reports/FBgn0003718 - gene - - - "l(1)comega247, l(1)2Bi, tlc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal" FBgn0005294 mei-2439 meiotic 2439 http://flybase.org/reports/FBgn0005294 - gene - - - "2439, mei-2439" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0060371 l(3)S137304c lethal (3) S137304c http://flybase.org/reports/FBgn0060371 gene - - - "1373/04, l(3)S137304c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262061 EG162 - http://flybase.org/reports/FBgn0262061 gene - - - EG162 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030759 CG13014 - http://flybase.org/reports/FBgn0030759 protein_coding_gene - - - CG13014 - CG13014 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable" FBgn0001452 l(1)7Df lethal (1) 7Df http://flybase.org/reports/FBgn0001452 - gene - - - l(1)7Df - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "egg chamber,germline clone,maternal effect" FBgn0051861 CG31861 - http://flybase.org/reports/FBgn0051861 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG17215, CG31861" - CG31861 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21665 K -0.356481981 -0.6689832 -0.435951315 -0.232123151 1.844786975 -0.541635829 FBgn0000350 corr corrugated wing http://flybase.org/reports/FBgn0000350 - gene - - - corr - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,cold sensitive" "wing,cold sensitive" FBgn0028872 CG18095 - http://flybase.org/reports/FBgn0028872 protein_coding_gene - - - "CG18095, DS05899.7, BG:DS05899.7" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG18095 11-Aug-17 DroID_v2017_08 "Drer\zgc:113307, Drer\ecm2, Drer\si:dkey-182i3.11, Drer\fmodb, Drer\kera, Drer\omd, Drer\fmoda, Drer\igfals" - "Cele\lron-15, Cele\sma-10" "Xtro\igfals, Xtro\bgn, Xtro\ecm2.2, Xtro\lum, Xtro\kera, Xtro\ogn" "Mmus\Prelp, Mmus\Bgn, Mmus\Kera, Mmus\Igfals, Mmus\Lum, Mmus\Fmod" "Hsap\PRELP, Hsap\BGN, Hsap\FMOD, Hsap\KERA, Hsap\IGFALS" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0065231 l(2)SH2172 lethal (2) SH2172 http://flybase.org/reports/FBgn0065231 gene - - - "l(2)SH2172, l(2)SH2 2172" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083279 E(smoDN)2364 Enhancer of smoDN 2364 http://flybase.org/reports/FBgn0083279 gene - - - E(smoDN)2364 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024657 l(2)k07813 lethal (2) k07813 http://flybase.org/reports/FBgn0024657 - gene - - - "78/13, l(2)k07813" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible" "imaginal disc,wing" FBgn0022107 l(2)k07015 lethal (2) k07015 http://flybase.net/reports/FBgn0022107.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0023499 HmpII HmpII http://flybase.org/reports/FBgn0023499 - gene - - - HmpII - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053739 snmRNA:430:CR33739 snmRNA:430:CR33739 http://flybase.org/reports/FBgn0053739 non_protein_coding_gene - - - "CR33739, snmRNA:430:CR33739" - CR33739 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014226 l(2)31Ee lethal (2) 31Ee http://flybase.org/reports/FBgn0014226 - gene - - - l(2)31Ee - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085651 CG41490 - http://flybase.org/reports/FBgn0085651 protein_coding_gene - - - CG41490 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037009 CG5104 - http://flybase.org/reports/FBgn0037009 protein_coding_gene - vesicle-mediated transport ; GO:0016192 | inferred from biological aspect of ancestor with PANTHER:PTN000566465 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011691 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000566465 "BcDNA:RH26504, CG5104" "IPR011691:Vesicle transport protein, SFT2-like, IPR007305:Vesicle transport protein, Got1/SFT2-like" CG5104 11-Aug-17 DroID_v2017_08 "Drer\sft2d3, Drer\sft2d1, Drer\zgc:112392, Drer\zgc:110788" Scer\SFT2 "Cele\F27D4.7, Cele\sftd-3" "Xtro\sft2d3, Xtro\sft2d1, Xtro\sft2d2" "Mmus\Sft2d3, Mmus\Sft2d2, Mmus\Sft2d1" "Hsap\SFT2D1, Hsap\SFT2D3, Hsap\SFT2D2" "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0021983 l(2)k09854 lethal (2) k09854 http://flybase.net/reports/FBgn0021983.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0034286 dpr13 defective proboscis extension response 13 http://flybase.org/reports/FBgn0034286 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG33996, CG12557, Dpr-13, CT34204, CG14493, dpr13, Dpr13, Dm_2R:58906" "IPR003598:Immunoglobulin subtype 2, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype" CG33996 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-163c2.2, Drer\si:dkey-65b12.12, Drer\LOC101885725, Drer\si:ch211-264f5.6, Drer\LOC101885444, Drer\LOC100333196" - Cele\zig-8 "Xtro\nfasc, Xtro\cadm2, Xtro\obsl1" Mmus\Amica1 - viable DRSC06464 E 1.212411109 -0.030263679 0.382473779 1.543605966 -0.001506058 0.593449396 FBgn0259649 B1365 - http://flybase.org/reports/FBgn0259649 gene - - - B1365 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "chaeta,ectopic,wing,distal" FBgn0062535 anon-6972 anon-6972 http://flybase.org/reports/FBgn0062535 gene - - - "6972, anon-6972" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034296 CG10912 - http://flybase.org/reports/FBgn0034296 protein_coding_gene - cold acclimation ; GO:0009631 | inferred from expression pattern - CG10912 IPR007931:Protein of unknown function DUF725 CG10912 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0017360 l(3)C18 lethal (3) C18 http://flybase.org/reports/FBgn0017360 - gene - - - "C18, l(3)C18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0065425 l(2)SH1515 lethal (2) SH1515 http://flybase.org/reports/FBgn0065425 gene - - - l(2)SH1515 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000932 fs(2)A2 female sterile (2) A2 http://flybase.org/reports/FBgn0000932 - gene - - - fs(2)A2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,mitotic cell cycle defective,lethal,maternal effect" "female reproductive system,maternal effect,spindle | maternal effect" FBgn0030610 CG9065 - http://flybase.org/reports/FBgn0030610 protein_coding_gene copper chaperone activity ; GO:0016531 | inferred from biological aspect of ancestor with PANTHER:PTN000423136 copper chaperone activity ; GO:0016531 | inferred from sequence or structural similarity with UniProtKB:Q14061 mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from biological aspect of ancestor with PANTHER:PTN000423137 copper ion transport ; GO:0006825 | inferred from biological aspect of ancestor with PANTHER:PTN000423136 respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with UniProtKB:Q14061 mitochondrial intermembrane space ; GO:0005758 | inferred from sequence or structural similarity with UniProtKB:Q14061 mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN000423137 "CG9065, COXS" "IPR007745:Cytochrome c oxidase copper chaperone, IPR009069:Cysteine alpha-hairpin motif superfamily" CG9065 11-Aug-17 DroID_v2017_08 Drer\cox17 Scer\COX17 Cele\cox-17 Xtro\cox17 Mmus\Cox17 Hsap\COX17 "viable,visible" trichogen cell DRSC20145 K -0.271205829 1.353639737 0.149653573 0.037868839 1.868271847 0.631868907 FBgn0038400 CG5903 - http://flybase.org/reports/FBgn0038400 protein_coding_gene - "cristae formation ; GO:0042407 | inferred from electronic annotation with InterPro:IPR019166, InterPro:IPR033182" "MICOS complex ; GO:0061617 | inferred from electronic annotation with InterPro:IPR019166, InterPro:IPR033182" "bs05g07.y1, anon-EST:Posey87, anon-WO0118547.99, CG5903" "IPR019166:MICOS complex subunit MIC26/MIC27, IPR033182:MICOS complex subunit MIC26/MIC27, animal" CG5903 11-Aug-17 DroID_v2017_08 "Drer\apooa, Drer\apoob, Drer\apool" - Cele\moma-1 "Xtro\apool, Xtro\apoo" "Mmus\Apoo, Mmus\Apool" "Hsap\APOOL, Hsap\APOO" "viable,fertile" FBgn0032980 CG16948 - http://flybase.org/reports/FBgn0032980 protein_coding_gene - - - CG16948 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039187 CG6454 - http://flybase.org/reports/FBgn0039187 protein_coding_gene clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium-dependent phospholipid binding ; GO:0005544 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 regulation of calcium ion-dependent exocytosis ; GO:0017158 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 CG6454 IPR000008:C2 domain CG6454 11-Aug-17 DroID_v2017_08 Drer\c2cd5 - Cele\F52H2.7 Xtro\c2cd5 Mmus\C2cd5 Hsap\C2CD5 viable FBgn0264330 CG43789 - http://flybase.org/reports/FBgn0264330 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43789 - CG43789 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064211 UY126 UY126 http://flybase.org/reports/FBgn0064211 gene - - - UY126 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0262377 mir-2a-1 mir-2a-1 stem loop http://flybase.org/reports/FBgn0262377 miRNA_gene - negative regulation of translational initiation ; GO:0045947 | inferred from direct assay negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "miR-2a-1, mir-2a-1, mir-2a, 2a-1, miR-2, dme-mir-2a-1, miR-2a, MIR-2, CR42899, miR2a, mir-2, CR32965, miR2, dme-miR-2a, dme-miR-2a-3p, dme-miR-2a-1" - CR42899 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage viable FBgn0267350 PI4KIIIalpha Phosphatidylinositol 4-kinase III alpha http://flybase.org/reports/FBgn0267350 protein_coding_gene 1-phosphatidylinositol 4-kinase activity ; GO:0004430 | inferred from biological aspect of ancestor with PANTHER:PTN000006021 1-phosphatidylinositol 4-kinase activity ; GO:0004430 | non-traceable author statement phosphatidylinositol-mediated signaling ; GO:0048015 | inferred from electronic annotation with InterPro:IPR015433 phosphorylation ; GO:0016310 | non-traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype plasma membrane organization ; GO:0007009 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype phosphatidylinositol phosphorylation ; GO:0046854 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype basement membrane organization ; GO:0071711 | inferred from mutant phenotype establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype hippo signaling ; GO:0035329 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000006021 "CG10260, PI4KIIIalpha, zw2, EG:BACR7C10.2, PI4K, Pi4KIIIalpha, stt4, PI4KIII[[alpha]], PI4KinaseIIIalpha, l(1)zw2, zw-2, ZW-2, l(1)VA722, l(1)17-59, l(1)3Ah, Stt4" "IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR001263:Phosphoinositide 3-kinase, accessory (PIK) domain, IPR011009:Protein kinase-like domain, IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR015433:Phosphatidylinositol kinase, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG10260 11-Aug-17 DroID_v2017_08 "Drer\pi4kab, Drer\pi4kaa" Scer\STT4 Cele\Y75B8A.24 Xtro\pi4ka Mmus\Pi4ka Hsap\PI4KA FBgn0003210 rb ruby http://flybase.org/reports/FBgn0003210 FBgn0025523 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with AP-1-2β intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002553 regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from mutant phenotype regulation of protein ubiquitination ; GO:0031396 | inferred from mutant phenotype synaptic vesicle coating ; GO:0016183 | traceable author statement eye pigment biosynthetic process ; GO:0006726 | traceable author statement lysosome organization ; GO:0007040 | inferred from sequence or structural similarity determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype intracellular transport ; GO:0046907 | traceable author statement Notch receptor processing ; GO:0007220 | inferred from mutant phenotype vesicle coating ; GO:0006901 | traceable author statement negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype clathrin adaptor complex ; GO:0030131 | inferred from electronic annotation with InterPro:IPR013037 coated vesicle ; GO:0030135 | traceable author statement synaptic vesicle ; GO:0008021 | traceable author statement AP-3 adaptor complex ; GO:0030123 | inferred from sequence or structural similarity with HGNC:567 "cg11427, CG11427, beta3, AP-3beta, rb, Rb, apl6" "IPR002553:Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR013037:Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain, IPR029390:AP-3 complex subunit beta, C-terminal domain, IPR026740:AP-3 complex subunit beta, IPR026739:AP complex subunit beta" CG11427 11-Aug-17 DroID_v2017_08 "Drer\ap3b2, Drer\LOC563316" Scer\APL6 Cele\apb-3 Xtro\ap3b2 "Mmus\Ap3b1, Mmus\Ap3b2" "Hsap\AP3B1, Hsap\AP3B2" " adult stage | female , adult stage , pharate adult stage | stage P13 , pupal stage , larval stage | third instar , embryonic stage " " subretinal glial cell

, pigment cell

, photoreceptor cell

, retina | restricted

, adult brain cortex | restricted

" "visual behavior defective,fertile,viable,eye color defective,recessive,visible,short lived,male" "secondary pigment cell pigment granule,tertiary pigment cell pigment granule,subretinal glial cell & pigment granule,pigment cell,ocellus pigment granule,testis pigment cell,Malpighian tubule,photoreceptor cell pigment granule" DRSC27940 K 0.716520771 -0.110183952 -0.015285235 0.11984677 2.044949488 0.328472739 FBgn0001640 l(1)dn20 lethal (1) discs normal 20 http://flybase.org/reports/FBgn0001640 - gene - - - "l(1)d.norm.-20, l(1)dn20" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0013318 Pcp21 Pupal-cuticle-protein-21kD http://flybase.org/reports/FBgn0013318 - gene - - - Pcp21 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262074 JC12 - http://flybase.org/reports/FBgn0262074 gene - response to anesthetic ; GO:0072347 | inferred from mutant phenotype - JC12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0028357 l(1)G0152 lethal (1) G0152 http://flybase.org/reports/FBgn0028357 gene - - - l(1)G0152 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044405 Scim22 Sensitized chromosome inheritance modifier 22 http://flybase.org/reports/FBgn0044405 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0016888 l(2)39DEm lethal (2) 39DEm http://flybase.org/reports/FBgn0016888 - gene - - - "K236, l(2)39DEm" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000571 extra-lamina-fiber extra lamina fiber http://flybase.org/reports/FBgn0000571 - gene - - - "opm37, H37, elf, extra-lamina-fiber" - - 11-Aug-17 DroID_v2017_08 - - - - - - lamina FBgn0040786 CG14104 - http://flybase.org/reports/FBgn0040786 protein_coding_gene - - - CG14104 "IPR010760:DNA repair protein, Swi5" CG14104 11-Aug-17 DroID_v2017_08 Drer\swi5 - - Xtro\swi5 Mmus\Swi5 Hsap\SWI5 "viable,fertile" DRSC10106 K 0.242932208 0.158863646 0.050333917 0.211046516 -0.052877052 1.504246204 FBgn0013686 mt:lrRNA mitochondrial large ribosomal RNA http://flybase.org/reports/FBgn0013686 "FBgn0002867, FBgn0025213, FBgn0025251, FBgn0025280" rRNA_gene structural constituent of ribosome ; GO:0003735 | non-traceable author statement pole cell formation ; GO:0007279 | traceable author statement P granule ; GO:0043186 | traceable author statement "CR34094, mtlrRNA, mlrRNA, 16S, mtlr RNA, mtrRNA, mt large rRNA, Lr mtDNA, mtlRNA, 16S mtRNA, 16SrRNA, mt 16S rRNA, 16S RNA, lrRNA, B4, anon-EST:fe2F10, anon-EST:fe1F3, anon-EST:fe1A1, mt:lrRNA, mt 16S rDNA, 16S rRNA, rRNA-16s, rrnL, LSU rRNA" - CR34094 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015803 RtGEF Rho-type guanine nucleotide exchange factor http://flybase.org/reports/FBgn0015803 - protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from electronic annotation with InterPro:IPR000219 guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from sequence or structural similarity with HGNC:15607 protein complex scaffold ; GO:0032947 | inferred from mutant phenotype regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype regulation of organ growth ; GO:0046620 | inferred from genetic interaction with Git inferred from genetic interaction with yki inferred from genetic interaction with hpo positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:15607 positive regulation of hippo signaling ; GO:0035332 | inferred from genetic interaction with yki inferred from genetic interaction with hpo muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay "dpix, rhoGEF, 38C.40, DrhoGEF, DrtGEF, RhoGEF, Rho/RacGEF, CG10043, ARHGEF7, beta-PIX, Pix, pix, dPix, rtGEF, betaPIX, RtGEF" "IPR000219:Dbl homology (DH) domain, IPR001452:SH3 domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG10043 11-Aug-17 DroID_v2017_08 "Drer\arhgef7a, Drer\plekhn1, Drer\arhgef6, Drer\arhgef7b" Scer\CDC24 Cele\pix-1 "Xtro\arhgef7, Xtro\arhgef6, Xtro\plekhn1" "Mmus\Plekhn1, Mmus\Arhgef6, Mmus\Arhgef7" "Hsap\ARHGEF7, Hsap\PLEKHN1, Hsap\ARHGEF6" " embryonic stage | stage 12-15 , adult stage && oogenesis stage , embryonic stage | stage 6-9 , adult stage && oogenesis stage | stage , follicle cell

, embryonic/larval digestive system

, ventral furrow

, oocyte

, nurse cell

, neuroblast | ventral

, stomodeal invagination

, posterior plate of cibarium

, amnioproctodeal invagination

, anterior midgut proper primordium

, cephalic furrow

,

ubiquitous , inclusive hindgut primordium

, mesoderm

, posterior midgut proper primordium

" "neuroanatomy defective,neurophysiology defective,viable,partially lethal - majority die" "postsynaptic membrane,synaptic vesiclePJ19),NMJ bouton,postsynaptic membranePJ19),t-bar" FBgn0044397 Scim30 Sensitized chromosome inheritance modifier 30 http://flybase.org/reports/FBgn0044397 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim30 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0013573 l(3)82Fa lethal (3) 82Fa http://flybase.org/reports/FBgn0013573 - gene - - - l(3)82Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal,recessive" mitotic cell cycle FBgn0262029 d dachs http://flybase.org/reports/FBgn0262029 protein_coding_gene "motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609 actin filament binding ; GO:0051015 | inferred from direct assay microfilament motor activity ; GO:0000146 | NOT inferred by curator from GO:0005524,GO:0016887 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1ZAY1 ATP binding ; GO:0005524 | NOT inferred from direct assay ATPase activity ; GO:0016887 | NOT inferred from direct assay protein complex scaffold ; GO:0032947 | inferred by curator from GO:0005515,GO:0051015 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Zyx" establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype positive regulation of growth ; GO:0045927 | inferred from mutant phenotype leg disc development ; GO:0035218 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609 myosin complex ; GO:0016459 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay "d, CG42840, Myo29D, CG10595, 29CD, AAF52683, 29C3-D1, clone 1.78, CG31610, anon-EST:Liang-1.78, l(2)c00146, D, dachs, CG13087, DmMyo20, Ds, Myo3A, Dachs" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001609:Myosin head, motor domain, IPR000048:IQ motif, EF-hand binding site" CG42840 11-Aug-17 DroID_v2017_08 "Drer\myo5aa, Drer\myo19, Drer\radil, Drer\LOC100006122, Drer\myo5c, Drer\myo5ab, Drer\rasip1, Drer\si:dkey-110c1.10, Drer\myo5b" "Scer\MYO4, Scer\SPC110" - "Xtro\myo19, Xtro\rasip1, Xtro\myo5a" "Mmus\Myo1g, Mmus\Myo5a, Mmus\Rasip1, Mmus\Myo5c, Mmus\Myo19, Mmus\Iqcb1, Mmus\Myo5b, Mmus\Myh10" "Hsap\MYO19, Hsap\MYO1G, Hsap\MYO5A, Hsap\RASIP1, Hsap\MYO5C, Hsap\MYO5B, Hsap\IQCB1" DRSC02191 I 2.369040264 0.353579274 0.276700613 0.277530314 -0.400055973 -0.710342409 FBgn0086671 snoRNA:Psi28S-2876 snoRNA:Psi28S-2876 http://flybase.org/reports/FBgn0086671 snoRNA_gene - - - "snoRNA:825, psi28S-2876, Psi28S-2876(SnoR825), snoR825, Psi28S-2876, snoRNA:Psi28S-2876, Dm-825, CR33646" - CR33646 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262003 CG42821 - http://flybase.org/reports/FBgn0262003 protein_coding_gene - - - "CG42821, BP1011, CG34035" IPR002350:Kazal domain CG42821 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052409 CG32409 - http://flybase.org/reports/FBgn0052409 protein_coding_gene - "ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000426674 ribosomal large subunit export from nucleus ; GO:0000055 | inferred from biological aspect of ancestor with PANTHER:PTN000426674 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000426674" "nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000426674 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000426674" "BcDNA:LD24586, CG32409" IPR007023:Ribosomal biogenesis regulatory protein CG32409 11-Aug-17 DroID_v2017_08 Drer\rrs1 Scer\RRS1 Cele\rrbs-1 - Mmus\Rrs1 Hsap\RRS1 "viable,visible" trichogen cell FBgn0033184 mEFTu2 mitochondrial translation elongation factor Tu 2 http://flybase.org/reports/FBgn0033184 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000005713 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with SGD:S000005713 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with UniProtKB:P49411" translational elongation ; GO:0006414 | inferred from sequence or structural similarity with SGD:S000005713 translational elongation ; GO:0006414 | inferred from sequence or structural similarity with UniProtKB:P49411 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000005713 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P49411 "CG12736, mEFTu2" "IPR000795:Transcription factor, GTP-binding domain, IPR004160:Translation elongation factor EFTu/EF1A, C-terminal, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR005225:Small GTP-binding protein domain, IPR031157:Tr-type G domain, conserved site, IPR033720:Elongation factor Tu, domain 2" CG12736 11-Aug-17 DroID_v2017_08 "Drer\eefsec, Drer\tufm" Scer\TUF1 "Cele\efsc-1, Cele\tufm-1, Cele\tufm-2" Xtro\eefsec "Mmus\Tufm, Mmus\Eefsec" "Hsap\EEFSEC, Hsap\TUFM" "viable,fertile" FBgn0051806 CG31806 - http://flybase.org/reports/FBgn0051806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4855, CG31806" - CG31806 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02787 IE 1.407661376 1.560435832 1.632418081 0.160877544 0.041521532 0.882709155 FBgn0004480 l(1)air5 lethal aberrant immune response 5 http://flybase.org/reports/FBgn0004480 - gene - - - l(1)air5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,melanotic mass phenotype,polyphasic" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass" FBgn0036369 CG10089 - http://flybase.org/reports/FBgn0036369 protein_coding_gene "protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR020417, InterPro:IPR020422 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement" "protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR020417, InterPro:IPR020422 protein dephosphorylation ; GO:0006470 | non-traceable author statement" cellular_component ; GO:0005575 | no biological data available CG10089 "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR020417:Atypical dual specificity phosphatase, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like" CG10089 11-Aug-17 DroID_v2017_08 "Drer\ssh1a, Drer\styxl1, Drer\si:ch211-195b15.8, Drer\dusp22a, Drer\si:ch211-203d1.3, Drer\dusp4, Drer\dusp5, Drer\ssh1b, Drer\dusp13a, Drer\dusp10, Drer\dusp3a, Drer\si:ch211-121a2.2, Drer\dusp3b, Drer\dusp19a, Drer\styx, Drer\dusp2, Drer\ssh2a, Drer\si:ch211-223p8.8, Drer\si:dkey-175m17.7, Drer\dusp16, Drer\ssh2b, Drer\dusp19b, Drer\dusp8b, Drer\dusp12, Drer\dusp22b" "Scer\MSG5, Scer\SDP1, Scer\YVH1, Scer\PPS1" "Cele\C24F3.2, Cele\C16A3.2, Cele\Y54F10BM.13" "Xtro\ssh2, Xtro\dusp12, Xtro\dupd1, Xtro\epm2a, Xtro\styxl1, Xtro\dusp22, Xtro\styx, Xtro\dusp26, Xtro\ssh1, Xtro\dusp22a, Xtro\dusp1, Xtro\dusp10, Xtro\dusp5, Xtro\dusp4, Xtro\dusp19" "Mmus\Dupd1, Mmus\Dusp1, Mmus\Dusp9, Mmus\Ssh1, Mmus\Dusp12, Mmus\Dusp2, Mmus\Dusp22, Mmus\Dusp19, Mmus\Ssh3, Mmus\Epm2a, Mmus\Dusp10, Mmus\Dusp8, Mmus\Dusp27, Mmus\Dusp15, Mmus\Dusp4, Mmus\Dusp16, Mmus\Styxl1, Mmus\Dusp13, Mmus\Dusp26, Mmus\Ssh2, Mmus\Styx, Mmus\Dusp3, Mmus\Dusp5" "Hsap\DUSP8, Hsap\SSH1, Hsap\SSH2, Hsap\DUSP13, Hsap\DUPD1, Hsap\DUSP10, Hsap\DUSP27, Hsap\DUSP3, Hsap\DUSP26, Hsap\DUSP22, Hsap\DUSP16, Hsap\STYXL1, Hsap\SSH3, Hsap\EPM2A, Hsap\DUSP5, Hsap\DUSP4, Hsap\DUSP15, Hsap\DUSP2, Hsap\DUSP1, Hsap\DUSP12, Hsap\DUSP9, Hsap\DUSP19, Hsap\STYX" viable FBgn0035882 CG13666 - http://flybase.org/reports/FBgn0035882 protein_coding_gene - - - CG13666 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036922 CG14182 - http://flybase.org/reports/FBgn0036922 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14182 - CG14182 11-Aug-17 DroID_v2017_08 "Drer\zgc:153595, Drer\gb:eh551987" - - Xtro\c16orf52 Mmus\BC030336 "Hsap\LOC102725138, Hsap\C16orf52" "viable,body color defective" mesothoracic tergum FBgn0022731 l(2)GPMG-6 lethal (2) GPMG-6 http://flybase.org/reports/FBgn0022731 - gene - - - "GPMG-6, l(2)GPMG-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045470 Gr93b Gustatory receptor 93b http://flybase.org/reports/FBgn0045470 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr93F2, CG13411, 93F.2, GR93F.2, CG31336, Gr93b, GR93b" IPR013604:7TM chemoreceptor CG31336 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - viable FBgn0025577 M(3)40l30 M(3)40l30 http://flybase.org/reports/FBgn0025577 - gene - - - M(3)40l30 - - 11-Aug-17 DroID_v2017_08 - - - - - - Minute FBgn0003571 Su(Pc)37D Suppressor of Polycomb at 37D http://flybase.org/reports/FBgn0003571 - gene - - - "Su(Pc), Su(Pc)37D" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030512 Nadsyn NAD synthetase http://flybase.org/reports/FBgn0030512 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003694, InterPro:IPR014445 glutaminase activity ; GO:0004359 | inferred from biological aspect of ancestor with PANTHER:PTN000557972 NAD+ synthase (glutamine-hydrolyzing) activity ; GO:0003952 | inferred from biological aspect of ancestor with PANTHER:PTN000557972" NAD biosynthetic process ; GO:0009435 | inferred from biological aspect of ancestor with PANTHER:PTN000557970 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000557970 "145027_at, Q9VYA0, NADS, CG9940, Nadsyn" "IPR003010:Carbon-nitrogen hydrolase, IPR003694:NAD(+) synthetase, IPR014445:Glutamine-dependent NAD(+) synthetase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR022310:NAD/GMP synthase" CG9940 11-Aug-17 DroID_v2017_08 Drer\nadsyn1 Scer\QNS1 Cele\qns-1 Xtro\nadsyn1 Mmus\Nadsyn1 Hsap\NADSYN1 viable FBgn0053542 upd3 unpaired 3 http://flybase.org/reports/FBgn0053542 protein_coding_gene cytokine activity ; GO:0005125 | traceable author statement cytokine activity ; GO:0005125 | non-traceable author statement cytokine activity ; GO:0005125 | inferred from direct assay embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from electronic annotation with InterPro:IPR031901 positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from direct assay inferred from mutant phenotype inferred from genetic interaction with hop inferred from genetic interaction with Stat92E inferred from genetic interaction with Socs36E inferred from genetic interaction with dome inferred from genetic interaction with Ptp61F JAK-STAT cascade ; GO:0007259 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype intestinal epithelial structure maintenance ; GO:0060729 | inferred from mutant phenotype paracrine signaling ; GO:0038001 | inferred from direct assay regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | inferred from genetic interaction with Stat92E immune response ; GO:0006955 | non-traceable author statement antimicrobial humoral response ; GO:0019730 | traceable author statement intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | traceable author statement extracellular space ; GO:0005615 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from direct assay "upd3, Upd3, CG5963, CG15062, UPD3, cg5963, cg15062, CG15062/CG5963, CG33542, upd-3, Upd-3, Upd-like, os, od, odsy, sy, unpaired 3" IPR031901:Unpaired protein CG33542 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,immune response defective,size defective,visible" "eye,border follicle cell,midgut,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 2,embryonic abdominal segment 1,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic head segment,posterior spiracle primordium,wing,posterior" FBgn0001861 l(1)10Ci lethal (1) 10Ci http://flybase.org/reports/FBgn0001861 - gene - - - l(1)10Ci - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0052304 obst-I obstructor-I http://flybase.org/reports/FBgn0052304 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG13805, obst-I, CG32304" IPR002557:Chitin binding domain CG32304 11-Aug-17 DroID_v2017_08 - - "Cele\F26D2.13, Cele\F07C4.11, Cele\F35E8.4, Cele\phat-5, Cele\cpg-1, Cele\Y46H3D.8, Cele\T05B4.9, Cele\R02F2.4, Cele\C39D10.7, Cele\phat-4, Cele\T05B4.10, Cele\T05B4.12, Cele\F35E8.6, Cele\F35E8.1, Cele\F07C4.10, Cele\T05B4.13, Cele\F16H6.3, Cele\cpg-2" - - - viable FBgn0003437 slim-bristle slim bristle http://flybase.org/reports/FBgn0003437 - gene - - - "smb, slim-bristle" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,viable,male fertile,visible" macrochaeta FBgn0082966 snoRNA:Psi28S-3327b snoRNA:Psi28S-3327b http://flybase.org/reports/FBgn0082966 snoRNA_gene - - - "snoRNA:Psi28S-3327b, Psi28S-3327b, psi28S-3327b, CR34643, pug28S-3327, chr3L:13016868..13016958" - CR34643 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020853 fs(3)A107 fs(3)A107 http://flybase.org/reports/FBgn0020853 - gene - - - "3-A107, fs(3)A107" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,female sterile" FBgn0026205 mie michelangelo http://flybase.org/reports/FBgn0026205 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available mie - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030940 CG15040 - http://flybase.org/reports/FBgn0030940 protein_coding_gene - - - CG15040 - CG15040 11-Aug-17 DroID_v2017_08 - - - Xtro\ahdc1 - - viable DRSC21482 IE 4.261909127 2.216553446 7.089192586 3.585175828 0.215368303 -0.05010909 FBgn0062677 EP2416 EP2416 http://flybase.org/reports/FBgn0062677 gene - - - EP2416 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014249 l(2)60Ab lethal (2) 60Ab http://flybase.org/reports/FBgn0014249 - gene - - - l(2)60Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039580 Gfat2 Glutamine:fructose-6-phosphate aminotransferase 2 http://flybase.org/reports/FBgn0039580 protein_coding_gene carbohydrate derivative binding ; GO:0097367 | inferred from electronic annotation with InterPro:IPR001347 glutamine-fructose-6-phosphate transaminase (isomerizing) activity ; GO:0004360 | inferred from electronic annotation with InterPro:IPR005855 carbohydrate derivative biosynthetic process ; GO:1901137 | inferred from electronic annotation with InterPro:IPR005855 sleep ; GO:0030431 | inferred from expression pattern - "CG1345, Dmel/GFAT2, Gfat2, gfat2" "IPR001347:Sugar isomerase (SIS), IPR005855:Glucosamine-fructose-6-phosphate aminotransferase, isomerising, IPR017932:Glutamine amidotransferase type 2 domain, IPR029055:Nucleophile aminohydrolases, N-terminal" CG1345 11-Aug-17 DroID_v2017_08 "Drer\gfpt1, Drer\LOC108179026, Drer\gfpt2" "Scer\YMR085W, Scer\YMR084W, Scer\GFA1" "Cele\gfat-1, Cele\gfat-2" "Xtro\gfpt2, Xtro\gfpt1" "Mmus\Gfpt2, Mmus\Gfpt1" "Hsap\GFPT1, Hsap\GFPT2" "lethal,viable" embryonic/larval brain FBgn0052129 tRNA:Pro-AGG-1-5 transfer RNA:Proline-AGG 1-5 http://flybase.org/reports/FBgn0052129 tRNA_gene CCU codon-amino acid adaptor activity ; GO:0033421 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033421 cytosol ; GO:0005829 | inferred by curator from GO:0033421 "AE002602.trna16-ProAGG, tRNA:P:AGG:AE002602-a, CR32129, chr3L.trna22-ProAGG, tRNA-Pro-AGG-1-5, tRNA:Pro-AGG-1-5, tRNA:CR32129, CCU" - CR32129 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266672 Sec8 Secretory 8 http://flybase.org/reports/FBgn0266672 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vesicle docking involved in exocytosis ; GO:0006904 | inferred from electronic annotation with InterPro:IPR007191 vesicle targeting ; GO:0006903 | inferred from biological aspect of ancestor with PANTHER:PTN000365473 meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity chemical synaptic transmission ; GO:0007268 | inferred from biological aspect of ancestor with PANTHER:PTN000365476 neurotransmitter secretion ; GO:0007269 | non-traceable author statement meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype vesicle tethering involved in exocytosis ; GO:0090522 | inferred by curator from GO:0000145 spermatid development ; GO:0007286 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000365473 actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype Golgi to plasma membrane transport ; GO:0006893 | inferred from biological aspect of ancestor with PANTHER:PTN000365473 synaptic vesicle targeting ; GO:0016080 | non-traceable author statement plasma membrane organization ; GO:0007009 | inferred from direct assay border follicle cell migration ; GO:0007298 | inferred from mutant phenotype synaptic vesicle docking ; GO:0016081 | non-traceable author statement regulation of synapse structure or activity ; GO:0050803 | inferred from mutant phenotype protein targeting to membrane ; GO:0006612 | inferred from biological aspect of ancestor with PANTHER:PTN000365473 growth cone membrane ; GO:0032584 | inferred from biological aspect of ancestor with PANTHER:PTN000365476 basal plasma membrane ; GO:0009925 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay exocyst ; GO:0000145 | inferred from direct assay exocyst ; GO:0000145 | non-traceable author statement membrane ; GO:0016020 | inferred from direct assay exocyst ; GO:0000145 | inferred from sequence or structural similarity apical plasma membrane ; GO:0016324 | inferred from direct assay synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000365476 exocyst ; GO:0000145 | inferred from biological aspect of ancestor with PANTHER:PTN000365473 "CG2095, sec8, Sec8, Sec8p, dsec8, fun" IPR007191:Sec8 exocyst complex component specific domain CG2095 11-Aug-17 DroID_v2017_08 Drer\exoc4 Scer\SEC8 Cele\sec-8 Xtro\exoc4 Mmus\Exoc4 Hsap\EXOC4 FBgn0003403 shy shy http://flybase.org/reports/FBgn0003403 - gene - - - shy - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" FBgn0261872 scaf6 SR-related CTD associated factor 6 http://flybase.org/reports/FBgn0261872 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR000061 RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR000061 - "scaf6, BP1040, CG6615, CG6626, CG14058, CG32168, CG33522, BP1047" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR006903:RNA polymerase II-binding domain, IPR000061:SWAP/Surp, IPR000467:G-patch domain, IPR006569:CID domain, IPR008942:ENTH/VHS" CG33522 11-Aug-17 DroID_v2017_08 "Drer\cherp, Drer\sf3a1" Scer\PRP21 Cele\tag-65 "Xtro\cherp, Xtro\sf3a1" "Mmus\Cherp, Mmus\Sf3a1" "Hsap\CHERP, Hsap\SF3A1" DRSC10676 I 2.047034402 0.476869647 -0.3036928 0.765182307 -0.266471715 0.059363214 FBgn0264869 CR44060 - http://flybase.org/reports/FBgn0264869 non_protein_coding_gene - - - CR44060 - CR44060 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067671 over-easy over easy http://flybase.org/reports/FBgn0067671 gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - over-easy - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0041119 l(2)cl-R11 lethal (2) cell lethal R11 http://flybase.org/reports/FBgn0041119 gene - - - "cl2R11, l(2)cl-R11, cl-R11" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266537 CR45098 - http://flybase.org/reports/FBgn0266537 non_protein_coding_gene - - - CR45098 - CR45098 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033955 CG12866 - http://flybase.org/reports/FBgn0033955 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG12866 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG12866 11-Aug-17 DroID_v2017_08 - "Scer\MCH5, Scer\ESBP6, Scer\MCH4, Scer\ATG22, Scer\MCH2" "Cele\mct-1, Cele\mct-2, Cele\gem-1, Cele\mct-3" - Mmus\Slc16a10 Hsap\SLC16A10 viable FBgn0002567 Rab32 Rab32 http://flybase.org/reports/FBgn0002567 "FBgn0015788, FBgn0062240" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 protein binding ; GO:0005515 | inferred from physical interaction with ca" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 regulation of neuron death ; GO:1901214 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q5S007 compound eye pigmentation ; GO:0048072 | inferred from genetic interaction with p melanosome organization ; GO:0032438 | inferred from biological aspect of ancestor with PANTHER:PTN000636041 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype inferred from genetic interaction with bmm regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype eye pigment precursor transport ; GO:0006856 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype synapse ; GO:0045202 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000636041 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000636119 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 melanosome ; GO:0042470 | inferred from biological aspect of ancestor with PANTHER:PTN000636041 autophagosome ; GO:0005776 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay "Rab-RP1/CG8024, CG8024, Rab-RP1, RabRP1, Rab32, DmRab32, DrabRP1, DRABR1, Rab-r1, anon-WO0118547.106, RAB-RP1, Rab32/RP1, rab32, beck, 24652026, 24652028, A1Z7S1, ltd, Rab7L1, Ltd" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR030697:Ras-related protein Rab29/Rab38/Rab32" CG8024 11-Aug-17 DroID_v2017_08 "Drer\rab32b, Drer\cracr2ab, Drer\rab38c, Drer\rab32a, Drer\rab38b, Drer\zgc:162171" Scer\YPT7 "Cele\ras-2, Cele\glo-1" "Xtro\rab32, Xtro\rab38, Xtro\LOC100496061" "Mmus\Rab29, Mmus\Rasef, Mmus\Mras, Mmus\Rab38, Mmus\Rab32" "Hsap\RAB38, Hsap\MRAS, Hsap\RAB29, Hsap\RAB32" "memory defective,viable,fertile,visible,recessive,neuroanatomy defective,eye color defective" "pigment cell,dopaminergic PPM1 neuron,dopaminergic PPL1 neuron,ocellus pigment granule,Malpighian tubule,primary pigment cell pigment granule,secondary pigment cell pigment granule,tertiary pigment cell pigment granule,eye photoreceptor cell & pigment granule" FBgn0014872 Pt13 Protein 13 http://flybase.org/reports/FBgn0014872 - gene - - - Pt13 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060873 l(3)S046020b lethal (3) S046020b http://flybase.org/reports/FBgn0060873 gene - - - "0460/20, l(3)S046020b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0052681 CG32681 - http://flybase.org/reports/FBgn0052681 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32681 - CG32681 11-Aug-17 DroID_v2017_08 - - - - - - DRSC17646 K -0.110735592 -0.010245136 -0.456635443 0.065189846 0.961738017 1.638462627 FBgn0052286 tRNA:Cys-GCA-1-4 transfer RNA:Cysteine-GCA 1-4 http://flybase.org/reports/FBgn0052286 tRNA_gene UGC codon-amino acid adaptor activity ; GO:0033414 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033414 cytosol ; GO:0005829 | inferred by curator from GO:0033414 "CR32286, AE002584.trna18-CysGCA, tRNA:C:GCA:AE002584-f, chr3L.trna18-CysGCA, tRNA:Cys-GCA-1-4, tRNA:CR32286, tRNA-Cys-GCA-1-4, UGC" - CR32286 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025388 CG12179 - http://flybase.org/reports/FBgn0025388 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "EG:66A1.2, CG12179" IPR029299:ALMS motif CG12179 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013972 Gycalpha99B Guanylyl cyclase alpha-subunit at 99B http://flybase.org/reports/FBgn0013972 FBgn0010227 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR011644 guanylate cyclase activity ; GO:0004383 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from direct assay "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 positive phototaxis ; GO:0046956 | inferred from mutant phenotype rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype cGMP biosynthetic process ; GO:0006182 | inferred from direct assay" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from direct assay" "Gycalpha-99B, dgc1, Gcalpha1, GYCa 99B, CG1912, dgca1, SGCalpha, gycalpha, dgcalpha1, Dgc1, Gycalpha63A, Gycalpha99B, sGCalpha99B, GCalpha1, sGC, Dgcalpha1, sGCalpha1" "IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR011644:Heme-NO binding, IPR024096:NO signalling/Golgi transport ligand-binding domain, IPR029787:Nucleotide cyclase, IPR011645:Haem NO binding associated" CG1912 11-Aug-17 DroID_v2017_08 "Drer\gucy1a2, Drer\gucy1b3, Drer\gucy1b2, Drer\gucy1a3" - - "Xtro\gucy1a2, Xtro\gucy1b3" "Mmus\Gucy1b2, Mmus\Gucy1a2, Mmus\Gucy1b3, Mmus\Gucy1a3" "Hsap\GUCY1A3, Hsap\GUCY1B3, Hsap\GUCY1A2" " adult stage , embryonic stage&&pupal stage " " adult brain

, adult head

, optic lobe

, thoracico-abdominal ganglion

" adult stage " retina

, neuropil

, thoracico-abdominal ganglion

, medulla

, adult head

, optic lobe

, lamina

, lobula plate neuropil

, adult brain

" "visual behavior defective,recessive,phototaxis defective,wild-type,neuroanatomy defective,viable" "photoreceptor cell R7,photoreceptor cell R8" FBgn0069411 JJF174 JJF174 http://flybase.org/reports/FBgn0069411 gene - - - JJF174 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0033367 PPO2 Prophenoloxidase 2 http://flybase.org/reports/FBgn0033367 protein_coding_gene L-DOPA monooxygenase activity ; GO:0036263 | inferred from direct assay dopamine monooxygenase activity ; GO:0036264 | inferred from direct assay melanotic encapsulation of foreign target ; GO:0035011 | inferred from genetic interaction with PPO3 melanization defense response ; GO:0035006 | inferred from mutant phenotype inferred from genetic interaction with PPO1 defense response to Gram-positive bacterium ; GO:0050830 | inferred from genetic interaction with PPO1 dopamine metabolic process ; GO:0042417 | inferred by curator from GO:0036264 defense response to fungus ; GO:0050832 | inferred from mutant phenotype inferred from genetic interaction with PPO1 extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "proPO45, CG8193, PPO2, DmePPO2, PO45, ProPO45, proPOA(3), proPo-A3" "IPR000896:Hemocyanin/hexamerin middle domain, IPR002227:Tyrosinase copper-binding domain, IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR008922:Uncharacterised domain, di-copper centre, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set" CG8193 11-Aug-17 DroID_v2017_08 - - - - - - "viable,immune response defective" crystal cell FBgn0003348 sdp sandpaper http://flybase.org/reports/FBgn0003348 - gene - - - sdp - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001791 l(1)Mb16 lethal (1) Mb16 http://flybase.org/reports/FBgn0001791 - gene - - - l(1)Mb16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031886 Nuf2 Nuf2 http://flybase.org/reports/FBgn0031886 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V3V7 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype Ndc80 complex ; GO:0031262 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay "anon-WO0118547.214, CG8902, l(2)SH2 2276, Nuf2, dmNuf2" IPR005549:Kinetochore protein Nuf2 CG8902 11-Aug-17 DroID_v2017_08 Drer\ccdc39 - - - - Hsap\CCDC39 "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,visible,partially lethal - majority die" "condensed nuclear chromosome,metaphase,nucleus,spindle,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0086379 BG01918 - http://flybase.org/reports/FBgn0086379 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01918 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective,long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective" FBgn0024660 l(2)k07160 lethal (2) k07160 http://flybase.org/reports/FBgn0024660 - gene - - - "71/60, l(2)k07160" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0262416 mir-31a mir-31a stem loop http://flybase.org/reports/FBgn0262416 miRNA_gene - segmentation ; GO:0035282 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-31a, mir-31a, miR-31a, MIR-31, CR42964, miR-31, CR33567, dme-miR-31a, mir-31, dme-miR-31a-5p" - CR42964 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015341 anon-65Ea anon-65Ea http://flybase.org/reports/FBgn0015341 - gene - - - anon-65Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038318 CG6236 - http://flybase.org/reports/FBgn0038318 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG6236, gi23171351, gi7299997, gi21357449" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG6236 11-Aug-17 DroID_v2017_08 - - "Cele\Y73F8A.35, Cele\F07C3.3, Cele\F15H10.7, Cele\Y41E3.1, Cele\F10C2.3" - - - FBgn0086200 CR42490 - http://flybase.org/reports/FBgn0086200 pseudogene_attribute - - - "BK003543, CG42490, HDC03087, CR42490" - CR42490 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267695 CR46031 - http://flybase.org/reports/FBgn0267695 non_protein_coding_gene - - - CR46031 - CR46031 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032022 CG14275 - http://flybase.org/reports/FBgn0032022 protein_coding_gene - - - "CT33900, BcDNA:RE73208, CG14275" - CG14275 11-Aug-17 DroID_v2017_08 - - "Cele\K11H12.6, Cele\K11H12.7, Cele\C15H9.9, Cele\F35C5.11" - - - viable FBgn0046334 en::hth en::hth http://flybase.org/reports/FBgn0046334 engineered_fusion_gene - - - "en::hth, EN-HTH" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,visible" "abdominal lateral pentascolopidial chordotonal organ lch5 | embryonic stage 16,lch5 ligament attachment cell | embryonic stage 16,eye,eye disc,ectopic,head capsule,ventral,antenna,maxillary palpus,antennal foramen,leg,chaeta,third segment of antenna,distal,tibia,coxa,trochanter,femur,tarsal segment,unguis,ventral thoracic disc,wing hinge,wing,wing margin,anterior,wing vein,wing disc,labellum" FBgn0001143 gs(1)N26 grandchildless N26 http://flybase.org/reports/FBgn0001143 - gene molecular_function ; GO:0003674 | no biological data available nuclear migration ; GO:0007097 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gs(1)N26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "grandchildless,heat sensitive" cleavage nucleus FBgn0026661 l(2)11B9 lethal (2) 11B9 http://flybase.org/reports/FBgn0026661 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)11B9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0082352 HM36 HM36 http://flybase.org/reports/FBgn0082352 gene - - - HM36 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001378 l(1)2Bj lethal (1) 2Bj http://flybase.org/reports/FBgn0001378 - gene - - - l(1)2Bj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic" FBgn0067883 Mod(Prat:bw)1-4 Mod(Prat:bw)1-4 http://flybase.org/reports/FBgn0067883 gene - - - "Mod-1-4, Mod(Prat:bw)1-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265992 CR44767 - http://flybase.org/reports/FBgn0265992 non_protein_coding_gene - - - "CR44767, lincRNA.177" - CR44767 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025008 E(tkv)D2 E(tkv)D2 http://flybase.org/reports/FBgn0025008 - gene - - - "D2, E(tkv)D2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051422 CG31422 - http://flybase.org/reports/FBgn0051422 protein_coding_gene - - - CG31422 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033752 CG8569 - http://flybase.org/reports/FBgn0033752 protein_coding_gene chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 transcription cofactor activity ; GO:0003712 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN001187210 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000371549 CG8569 "IPR000313:PWWP domain, IPR002893:Zinc finger, MYND-type, IPR001487:Bromodomain" CG8569 11-Aug-17 DroID_v2017_08 "Drer\prkcbp1l, Drer\zmynd8, Drer\zmynd11" Scer\RCO1 "Cele\bra-1, Cele\bra-2" Xtro\zmynd11 "Mmus\Zmynd8, Mmus\Zmynd11" Hsap\ZMYND11 "viable,visible" mesothoracic tergum FBgn0004771 l(3)89Ej lethal (3) 89Ej http://flybase.org/reports/FBgn0004771 - gene - - - l(3)89Ej - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0060396 l(3)S132301 lethal (3) S132301 http://flybase.org/reports/FBgn0060396 gene - - - "1323/01, l(3)S132301" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0034971 CG3209 - http://flybase.org/reports/FBgn0034971 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR002123" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002123 instar larval development ; GO:0002168 | inferred from mutant phenotype response to insulin ; GO:0032868 | inferred from mutant phenotype ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay "CG3209, GPAT4, dGPAT4" IPR002123:Phospholipid/glycerol acyltransferase CG3209 11-Aug-17 DroID_v2017_08 "Drer\agpat9l, Drer\gpat4, Drer\gpat3, Drer\aup1" - "Cele\acl-4, Cele\acl-5" "Xtro\gpat4, Xtro\gpat3" "Mmus\Aup1, Mmus\Gpat4, Mmus\Agpat9" "Hsap\GPAT3, Hsap\AUP1, Hsap\GPAT4" viable FBgn0038783 CG4367 - http://flybase.org/reports/FBgn0038783 protein_coding_gene - - - CG4367 "IPR004302:Cellulose/chitin-binding protein, N-terminal" CG4367 11-Aug-17 DroID_v2017_08 - - - - Mmus\Defb46 - "partially lethal - majority die,some die during pupal stage" FBgn0087017 l(3)61De lethal (3) 61De http://flybase.org/reports/FBgn0087017 gene - - - l(3)61De - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0052438 SMC5 Structural maintenance of chromosomes 5 http://flybase.org/reports/FBgn0052438 protein_coding_gene ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with SGD:S000005394 damaged DNA binding ; GO:0003684 | inferred from sequence or structural similarity with SGD:S000005394 SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000005394 double-strand break repair via homologous recombination ; GO:0000724 | inferred from electronic annotation with InterPro:IPR027131 sister chromatid cohesion ; GO:0007062 | inferred from electronic annotation with InterPro:IPR027131 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000005394 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype response to caffeine ; GO:0031000 | inferred from mutant phenotype Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000005394 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005394 "DmSMC5, SMC5, CG7783, CG32438, Smc5, AAF51749, smc5" "IPR003395:RecF/RecN/SMC, N-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027131:Structural maintenance of chromosomes protein 5" CG32438 11-Aug-17 DroID_v2017_08 Drer\smc5 Scer\SMC5 Cele\smc-5 Xtro\smc5 Mmus\Smc5 Hsap\SMC5 "viable,lethal,conditional,chemical sensitive,radiation sensitive" FBgn0037579 COX7AL Cytochrome c oxidase subunit 7A-like http://flybase.org/reports/FBgn0037579 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P24310 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProtKB:P24310" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P24310 "VIIa, CG18193, COXK, COXJ, COX7AL" "IPR003177:Cytochrome c oxidase, subunit VIIa" CG18193 11-Aug-17 DroID_v2017_08 "Drer\cox7a2a, Drer\cox7a3, Drer\cox7a1, Drer\cox7a2b" - - "Xtro\LOC100127850, Xtro\cox7a2, Xtro\cox7a2l" "Mmus\Cox7a2l, Mmus\Cox7a2, Mmus\Cox7a1" "Hsap\COX7A2L, Hsap\COX7A2, Hsap\COX7A1" FBgn0260248 GSd430 - http://flybase.org/reports/FBgn0260248 gene - - - GSd430 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085819 28SrRNA-Psi:CR41609 28S ribosomal RNA pseudogene:CR41609 http://flybase.org/reports/FBgn0085819 pseudogene_attribute - - - "CR41609, 28SrRNA-Psi:CR41609" - CR41609 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264326 DNApol-epsilon255 DNA polymerase epsilon 255kD subunit http://flybase.org/reports/FBgn0264326 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR013697 nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR006134, InterPro:IPR006172 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000072300 single-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008310 | inferred from biological aspect of ancestor with PANTHER:PTN000072300 DNA-directed DNA polymerase activity ; GO:0003887 | non-traceable author statement DNA-directed DNA polymerase activity ; GO:0003887 | inferred from direct assay 3'-5'-exodeoxyribonuclease activity ; GO:0008296 | inferred from direct assay" "nucleotide-excision repair, DNA gap filling ; GO:0006297 | inferred from biological aspect of ancestor with PANTHER:PTN000072300 organ growth ; GO:0035265 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype base-excision repair, gap-filling ; GO:0006287 | inferred from biological aspect of ancestor with PANTHER:PTN000072300 DNA-dependent DNA replication ; GO:0006261 | inferred from direct assay endomitotic cell cycle ; GO:0007113 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA replication proofreading ; GO:0045004 | inferred from biological aspect of ancestor with PANTHER:PTN000072300 leading strand elongation ; GO:0006272 | inferred from biological aspect of ancestor with PANTHER:PTN000072300" epsilon DNA polymerase complex ; GO:0008622 | inferred from biological aspect of ancestor with PANTHER:PTN000072300 nucleus ; GO:0005634 | inferred from direct assay epsilon DNA polymerase complex ; GO:0008622 | inferred from sequence or structural similarity "l(3)pl10, pl[10], l(3)pl10R, DNApol-epsilon, CG6768, BAB17608, pol-epsilon, 6768, dpolepsilon, dpolepsilonp255, DNA pol epsilon, DNApol-epsilon255" "IPR006133:DNA-directed DNA polymerase, family B, exonuclease domain, IPR006134:DNA-directed DNA polymerase, family B, multifunctional domain, IPR012337:Ribonuclease H-like domain, IPR013697:DNA polymerase epsilon, catalytic subunit A, C-terminal, IPR006172:DNA-directed DNA polymerase, family B, IPR023211:DNA polymerase, palm domain, IPR029703:DNA polymerase epsilon catalytic subunit" CG6768 11-Aug-17 DroID_v2017_08 Drer\pole Scer\POL2 Cele\pole-1 Xtro\pole Mmus\Pole Hsap\POLE " adult stage | male , egg stage | unfertilized egg , embryonic stage--pupal stage , adult stage | female " unfertilized egg

FBgn0004538 l(4)102EFf lethal (4) 102EFf http://flybase.org/reports/FBgn0004538 - gene - - - "l(4)19, l(4)102EFf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005538 l(3)72Df lethal (3) 72Df http://flybase.org/reports/FBgn0005538 - gene - - - "1(3)72Df, l(3)72Df" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034110 Atg9 Autophagy-related 9 http://flybase.org/reports/FBgn0034110 protein_coding_gene molecular_function ; GO:0003674 | no biological data available late nucleophagy ; GO:0044805 | inferred from biological aspect of ancestor with PANTHER:PTN000315580 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000315580 piecemeal microautophagy of nucleus ; GO:0034727 | inferred from biological aspect of ancestor with PANTHER:PTN000315580 positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype inferred from genetic interaction with bsk inferred from genetic interaction with puc positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype glycophagy ; GO:0061723 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from sequence or structural similarity with SGD:S000002308 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype protein localization to pre-autophagosomal structure ; GO:0034497 | inferred from biological aspect of ancestor with PANTHER:PTN000315580 integral component of membrane ; GO:0016021 | inferred from sequence model cytoplasm ; GO:0005737 | inferred from direct assay cell junction ; GO:0030054 | inferred from direct assay autophagosome ; GO:0005776 | inferred from biological aspect of ancestor with PANTHER:PTN000315580 pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN000315580 "Atg9, CG3615, atg9, ATG9, dAtg9" IPR007241:Autophagy-related protein 9 CG3615 11-Aug-17 DroID_v2017_08 "Drer\atg9a, Drer\atg9b" Scer\ATG9 Cele\atg-9 "Xtro\atg9b, Xtro\atg9a" "Mmus\Atg9a, Mmus\Atg9b" "Hsap\ATG9A, Hsap\ATG9B, Hsap\ABCB6" pupal stage salivary gland

"viable,visible,increased cell death" "embryonic/larval fat body,somatic clone | third instar larval stage,intestinal stem cell,chemical conditional,eye,eye disc | third instar larval stage" FBgn0000507 anon-61Fa anon-61Fa http://flybase.org/reports/FBgn0000507 - gene - - - "dsx-c61F, anon-61Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035617 l(3)psg2 lethal (3) persistent salivary gland 2 http://flybase.org/reports/FBgn0035617 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "clone 1.47, anon-EST:Liang-1.47, psg2, CG5146, l(3)psg2" - CG5146 11-Aug-17 DroID_v2017_08 Drer\srrm1 - "Cele\spat-3, Cele\rsr-1" - "Mmus\Srrm1, Mmus\Zc3h13" "Hsap\ZC3H13, Hsap\SRRM1" "some die during P-stage,lethal - all die before end of P-stage,recessive,lethal,viable" "embryonic/larval salivary gland,leg" FBgn0013544 l(2)F11 lethal (2) F11 http://flybase.org/reports/FBgn0013544 - gene - - - l(2)F11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003311 sab straight abdomen http://flybase.org/reports/FBgn0003311 - gene - - - sab - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,male fertile" "abdomen,macrochaeta" FBgn0267558 CR45898 - http://flybase.org/reports/FBgn0267558 non_protein_coding_gene - - - CR45898 - CR45898 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025118 tRNA:Pro-CGG-3-1 transfer RNA:Proline-CGG 3-1 http://flybase.org/reports/FBgn0025118 "FBgn0052784, FBgn0060119" tRNA_gene CCG codon-amino acid adaptor activity ; GO:0033424 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033424 cytosol ; GO:0005829 | inferred by curator from GO:0033424 "AE002566.trna2-ProCGG, tRNA:P:CGG:AE002566, CR32784, EG:EG0002.4, chrX.trna2-ProCGG, tRNA-Pro-CGG-3-1, tRNA:Pro-CGG-3-1, tRNA:P:3E, CCG" - CR32784 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037807 CG6293 - http://flybase.org/reports/FBgn0037807 protein_coding_gene "transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR006042, InterPro:IPR006043" "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR006042, InterPro:IPR006043" "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006042, InterPro:IPR006043" CG6293 "IPR006042:Xanthine/uracil permease, IPR006043:Xanthine/uracil/vitamin C permease" CG6293 11-Aug-17 DroID_v2017_08 "Drer\slc23a2, Drer\zgc:110789, Drer\slc23a1, Drer\si:dkey-106n21.1, Drer\slc23a3" - "Cele\T07G12.4, Cele\T07G12.5, Cele\R11E3.2, Cele\T07G12.2, Cele\Y59E9AL.4, Cele\C51E3.6" "Xtro\slc23a2, Xtro\LOC100486632, Xtro\slc23a3, Xtro\slc23a1" "Mmus\Slc23a1, Mmus\Slc23a2, Mmus\Slc23a4, Mmus\Slc23a3" "Hsap\SLC23A2, Hsap\SLC23A1, Hsap\SLC23A3" viable FBgn0265594 CR44421 - http://flybase.org/reports/FBgn0265594 non_protein_coding_gene - - - CR44421 - CR44421 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265815 CR44604 - http://flybase.org/reports/FBgn0265815 non_protein_coding_gene - - - "lincRNA.178, CR44604" - CR44604 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083943 CG34107 - http://flybase.org/reports/FBgn0083943 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12816, CG34107" IPR026507:Uncharacterised protein family UPF0691 CG34107 11-Aug-17 DroID_v2017_08 Drer\si:ch211-248e11.2 - - - "Mmus\Ccpg1os, Mmus\1700007K13Rik" "Hsap\C9orf116, Hsap\C15orf65" FBgn0025639 Hmt4-20 Histone methyltransferase 4-20 http://flybase.org/reports/FBgn0025639 FBgn0047197 protein_coding_gene histone methyltransferase activity (H4-K20 specific) ; GO:0042799 | inferred from direct assay histone methyltransferase activity (H4-K20 specific) ; GO:0042799 | inferred from mutant phenotype "regulation of gene expression, epigenetic ; GO:0040029 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype histone H4-K20 methylation ; GO:0034770 | inferred from mutant phenotype histone H4-K20 dimethylation ; GO:0034772 | inferred from mutant phenotype histone methylation ; GO:0016571 | inferred from direct assay inferred from mutant phenotype histone H4-K20 trimethylation ; GO:0034773 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nuclear heterochromatin ; GO:0005720 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "hmt4-20, SUV4-20, CG13363, EG:115C2.10, BcDNA:LD36415, Suv4-20, Su(var)4-20, Hmt4-20, Suv4.20, dSuv4-20" "IPR025790:Histone-lysine N-methyltransferase, Suvar4-20, IPR001214:SET domain" CG13363 11-Aug-17 DroID_v2017_08 "Drer\suv420h2, Drer\suv420h1" - Cele\set-4 Xtro\kmt5b "Mmus\Kmt5b, Mmus\Kmt5c" "Hsap\KMT5C, Hsap\KMT5B" "viable,suppressor of variegation,dominant,non-suppressor of variegation,fertile" DRSC18482 EK -0.263525304 -1.113695018 0.500365989 -2.469161281 -2.229715643 -0.229358561 FBgn0001661 l(1)E7 lethal (1) E7 http://flybase.org/reports/FBgn0001661 - gene - - - "l(1)E7[ts], l(1)E7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,heat sensitive" FBgn0016973 toto toto http://flybase.org/reports/FBgn0016973 - gene - - - toto - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0039482 CG14258 - http://flybase.org/reports/FBgn0039482 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG14258 IPR010562:Haemolymph juvenile hormone binding CG14258 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033427 Smyd4-1 "SET and MYND domain containing, class 4, member 1" http://flybase.org/reports/FBgn0033427 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Smyd4-1, CG1868" "IPR001214:SET domain, IPR011990:Tetratricopeptide-like helical domain, IPR002893:Zinc finger, MYND-type" CG1868 11-Aug-17 DroID_v2017_08 "Drer\smyd1a, Drer\smyd1b, Drer\smyd3, Drer\smyd2a, Drer\smyd5, Drer\smyd2b, Drer\smyd4" "Scer\SET5, Scer\SET6" "Cele\set-3, Cele\set-30" "Xtro\smyd5, Xtro\smyd4, Xtro\smyd1" "Mmus\Smyd2, Mmus\Smyd1, Mmus\Smyd3, Mmus\Smyd5, Mmus\Smyd4" "Hsap\SMYD5, Hsap\SMYD3, Hsap\SMYD2, Hsap\SMYD4, Hsap\SMYD1" viable DRSC06785 K 0.884894579 -0.182451479 -0.279130319 -0.12865075 -0.80743014 -1.6166405 FBgn0033793 CG3955 - http://flybase.org/reports/FBgn0033793 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN001048184 CG3955 - CG3955 11-Aug-17 DroID_v2017_08 "Drer\LOC103910141, Drer\LOC100535643" - "Cele\D1081.6, Cele\ZK757.10, Cele\C24D10.49" - "Mmus\2010109I03Rik, Mmus\Gm9513, Mmus\Ly6c2, Mmus\Ly6a, Mmus\Gm17727, Mmus\Ly6d" Hsap\LY6D "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0039059 CG13829 - http://flybase.org/reports/FBgn0039059 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from electronic annotation with InterPro:IPR019013 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13829 IPR019013:Vacuolar ATPase assembly integral membrane protein Vma21 CG13829 11-Aug-17 DroID_v2017_08 Drer\vma21 Scer\VMA21 "Cele\pdcd-2, Cele\R07E5.7" Xtro\vma21 Mmus\Vma21 Hsap\VMA21 viable FBgn0030460 CG2453 - http://flybase.org/reports/FBgn0030460 protein_coding_gene "2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0043334 | inferred from sequence or structural similarity with UniProtKB:P49017" ubiquinone biosynthetic process ; GO:0006744 | inferred from sequence or structural similarity with UniProtKB:P49017 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P49017 CG2453 "IPR004033:UbiE/COQ5 methyltransferase, IPR023576:UbiE/COQ5 methyltransferase, conserved site, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG2453 11-Aug-17 DroID_v2017_08 Drer\coq5 Scer\COQ5 Cele\coq-5 Xtro\coq5 Mmus\Coq5 Hsap\COQ5 viable FBgn0043986 Su(rst)E252 Su(rst)E252 http://flybase.org/reports/FBgn0043986 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E252, Su(rst)E252" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065504 l(2)SH1201 lethal (2) SH1201 http://flybase.org/reports/FBgn0065504 gene - - - "l(2)SH1201, l(2)SH2 1201" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036877 CG9452 - http://flybase.org/reports/FBgn0036877 protein_coding_gene acid phosphatase activity ; GO:0003993 | inferred from sequence or structural similarity with HGNC:125 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:125 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:125 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:125 CG9452 "IPR029630:Venom acid phosphatase Acph-1, IPR029033:Histidine phosphatase superfamily, IPR000560:Histidine phosphatase superfamily, clade-2, IPR033379:Histidine acid phosphatase active site" CG9452 11-Aug-17 DroID_v2017_08 "Drer\acp2, Drer\pxylp1, Drer\acp6" - "Cele\acp-7, Cele\pho-11, Cele\F26C11.1, Cele\C27A2.12, Cele\pho-10, Cele\pho-13, Cele\acp-4, Cele\acp-6, Cele\ZK792.1, Cele\pho-12, Cele\pho-7, Cele\acp-2, Cele\pho-5, Cele\pho-6, Cele\acp-1, Cele\ZK809.9, Cele\pho-1, Cele\pho-14, Cele\acp-3, Cele\pho-8, Cele\pho-9, Cele\acp-5, Cele\pho-4" "Xtro\acp6, Xtro\acp2, Xtro\LOC100494856" "Mmus\Pxylp1, Mmus\Acp6, Mmus\Acpp, Mmus\Acp2, Mmus\Acpt" "Hsap\PXYLP1, Hsap\ACP2, Hsap\ACP6, Hsap\ACPP, Hsap\ACPT" FBgn0267286 CR45722 - http://flybase.org/reports/FBgn0267286 non_protein_coding_gene - - - CR45722 - CR45722 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038423 CG10317 - http://flybase.org/reports/FBgn0038423 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10317 - CG10317 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085249 CG34220 - http://flybase.org/reports/FBgn0085249 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG34220 IPR002557:Chitin binding domain CG34220 11-Aug-17 DroID_v2017_08 Drer\mansc1 Scer\AGA1 - - - - FBgn0002039 l(2)37Dc lethal (2) 37Dc http://flybase.org/reports/FBgn0002039 - gene - - - "E106, l(2)E106, l(2)37Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003164 puff puff http://flybase.org/reports/FBgn0003164 - gene - - - "puf, puff" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,3rd posterior cell" FBgn0070040 3R-40-7 3R-40-7 http://flybase.org/reports/FBgn0070040 gene molecular_function ; GO:0003674 | no biological data available chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-40-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg,germline clone,maternal effect,embryonic/first instar larval cuticle" FBgn0069221 gl(2R)279-37 gl(2R)279-37 http://flybase.org/reports/FBgn0069221 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2R)279-37 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,terminal phenotype,germline clone,maternal effect,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage" "denticle belt,germline clone,maternal effect" FBgn0267872 CR46160 - http://flybase.org/reports/FBgn0267872 pseudogene_attribute - - - "CR46160, CG12717-related" - CR46160 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001795 l(1)Mb28 lethal (1) Mb28 http://flybase.org/reports/FBgn0001795 - gene - - - l(1)Mb28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing margin bristle,wing" FBgn0053490 CG33490 - http://flybase.org/reports/FBgn0053490 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6110, CG33490" - CG33490 11-Aug-17 DroID_v2017_08 Drer\efhb - - - Mmus\Efhb Hsap\EFHB viable FBgn0262988 CG43296 - http://flybase.org/reports/FBgn0262988 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43296 - CG43296 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051606 CG31606 - http://flybase.org/reports/FBgn0051606 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31606 - CG31606 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085531 CG40878 - http://flybase.org/reports/FBgn0085531 protein_coding_gene - - - CG40878 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051248 CG31248 - http://flybase.org/reports/FBgn0051248 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 "CG2640, CG31248" IPR016181:Acyl-CoA N-acyltransferase CG31248 11-Aug-17 DroID_v2017_08 - - "Cele\anat-1, Cele\T10B5.4, Cele\R05H10.7" - - - "viable,fertile" DRSC22722 K -0.06094311 0.507407235 -0.345191931 0.21199347 0.080595505 1.557650338 FBgn0038327 Trax Translin associated factor X http://flybase.org/reports/FBgn0038327 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR002848, InterPro:IPR016068, InterPro:IPR016069 endoribonuclease activity ; GO:0004521 | inferred from direct assay" "RNA phosphodiester bond hydrolysis, endonucleolytic ; GO:0090502 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay "trax, CG5063, Trax" "IPR002848:Translin family, IPR016068:Translin, N-terminal" CG5063 11-Aug-17 DroID_v2017_08 Drer\tsnax - - Xtro\tsnax Mmus\Tsnax Hsap\TSNAX "female fertile,viable" FBgn0032343 CG6201 - http://flybase.org/reports/FBgn0032343 protein_coding_gene L-iduronidase activity ; GO:0003940 | inferred from biological aspect of ancestor with PANTHER:PTN000290543 carbohydrate metabolic process ; GO:0005975 | inferred from biological aspect of ancestor with PANTHER:PTN000290543 - CG6201 "IPR000514:Glycoside hydrolase, family 39, IPR017853:Glycoside hydrolase superfamily" CG6201 11-Aug-17 DroID_v2017_08 Drer\idua - - Xtro\idua Mmus\Idua Hsap\IDUA "partially lethal - majority die,some die during pupal stage" FBgn0040083 p78 p78 http://flybase.org/reports/FBgn0040083 gene - - - p78 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262215 mir-989 mir-989 stem loop http://flybase.org/reports/FBgn0262215 miRNA_gene - border follicle cell migration ; GO:0007298 | inferred from mutant phenotype - "dme-mir-989, miR-989, mir-989, MIR-989, CR42922, lincRNA.307, dme-miR-989" - CR42922 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage" "eye,wing,wing margin,wing vein L2,male limited,wing vein L4,wing vein L5,wing vein,border follicle cell,somatic clone" FBgn0022814 E(faf)E254 Enhancer of faf E254 http://flybase.org/reports/FBgn0022814 - gene - - - E(faf)E254 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085763 CR40659 - http://flybase.org/reports/FBgn0085763 non_protein_coding_gene - - - CR40659 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037721 CG9427 - http://flybase.org/reports/FBgn0037721 protein_coding_gene - - - CG9427 "IPR004911:Gamma interferon inducible lysosomal thiol reductase GILT, IPR012336:Thioredoxin-like fold" CG9427 11-Aug-17 DroID_v2017_08 "Drer\ifi30, Drer\si:dkey-197i20.6" - "Cele\ZK669.3, Cele\Y18D10A.2, Cele\F37H8.5, Cele\R07E5.4, Cele\ZK669.2, Cele\pqn-48, Cele\W04A4.3, Cele\C02D5.2" Xtro\ifi30 Mmus\Ifi30 Hsap\IFI30 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037336 CG2519 - http://flybase.org/reports/FBgn0037336 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2519 - CG2519 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0065913 l(2)SH0174 lethal (2) SH0174 http://flybase.org/reports/FBgn0065913 gene - - - l(2)SH0174 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265266 CG13639 - http://flybase.org/reports/FBgn0265266 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13639, anon-SAGE:Wang-045" - CG13639 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033650 CG13193 - http://flybase.org/reports/FBgn0033650 protein_coding_gene - - - CG13193 IPR010512:Protein of unknown function DUF1091 CG13193 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034399 CG15083 - http://flybase.org/reports/FBgn0034399 protein_coding_gene - - - "BcDNA:RH17222, CG15083" - CG15083 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval hemocyte | third instar larval stage FBgn0085290 CG34261 - http://flybase.org/reports/FBgn0085290 protein_coding_gene purine nucleoside binding ; GO:0001883 | inferred from sequence or structural similarity with HGNC:21257 purine nucleoside metabolic process ; GO:0042278 | inferred from sequence or structural similarity with HGNC:21257 cellular_component ; GO:0005575 | no biological data available CG34261 IPR002589:Macro domain CG34261 11-Aug-17 DroID_v2017_08 "Drer\oard1, Drer\zgc:113436" Scer\POA1 "Cele\fbxb-37, Cele\F54G2.2, Cele\W08F4.12" - Mmus\Oard1 Hsap\OARD1 FBgn0065315 l(2)SH1929 lethal (2) SH1929 http://flybase.org/reports/FBgn0065315 gene - - - "l(2)SH1929, l(2)SH2 1929" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034000 CG11808 - http://flybase.org/reports/FBgn0034000 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG11808 - CG11808 11-Aug-17 DroID_v2017_08 Drer\rsrc1 - - - Mmus\Rsrc1 - viable FBgn0264371 CR43823 - http://flybase.org/reports/FBgn0264371 non_protein_coding_gene - - - CR43823 - CR43823 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002785 mot-28 mottled 28 http://flybase.org/reports/FBgn0002785 - gene - - - "Mot[28], mot-28" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,cold sensitive" pigment cell FBgn0259558 B1250 - http://flybase.org/reports/FBgn0259558 gene - - - B1250 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051682 Tengl1 Testis EndoG-Like 1 http://flybase.org/reports/FBgn0051682 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - "BcDNA:AT02809, CG17006, CG31682, Tengl1" "IPR001604:DNA/RNA non-specific endonuclease, IPR020821:Extracellular Endonuclease, subunit A" CG31682 11-Aug-17 DroID_v2017_08 "Drer\endog, Drer\LOC103910196, Drer\LOC100333474" Scer\NUC1 Cele\cps-6 "Xtro\exog, Xtro\endog" "Mmus\Exog, Mmus\Endog" "Hsap\EXOG, Hsap\ENDOG" viable FBgn0030926 psh persephone http://flybase.org/reports/FBgn0030926 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 peptidase activity ; GO:0008233 | traceable author statement peptidase activity ; GO:0008233 | inferred from mutant phenotype serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" defense response ; GO:0006952 | inferred from genetic interaction with grass regulation of Toll signaling pathway ; GO:0008592 | traceable author statement positive regulation of antifungal peptide biosynthetic process ; GO:0006967 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | traceable author statement proteolysis ; GO:0006508 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from direct assay proteolysis ; GO:0006508 | inferred from sequence model proteolysis ; GO:0006508 | traceable author statement extracellular region ; GO:0005576 | inferred from direct assay "SP28, c-SP28, CG6367, psh, Psh" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site, IPR022700:Proteinase, regulatory CLIP domain" CG6367 11-Aug-17 DroID_v2017_08 - - Cele\try-3 "Xtro\c1s, Xtro\masp2" - - "immune response defective,viable" FBgn0005161 l(2)G156 lethal (2) G156 http://flybase.org/reports/FBgn0005161 - gene - - - l(2)G156 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065717 l(2)SH0577 lethal (2) SH0577 http://flybase.org/reports/FBgn0065717 gene - - - "l(2)SH0577, l(2)SH2 0577" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262963 CR43274 - http://flybase.org/reports/FBgn0262963 non_protein_coding_gene - - - "CR43274, lincRNA.175" - CR43274 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265812 CR44601 - http://flybase.org/reports/FBgn0265812 non_protein_coding_gene - - - "lincRNA.158, CR44601" - CR44601 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017649 E(Brd)M10 Enhancer of Bearded http://flybase.org/reports/FBgn0017649 - gene - - - E(Brd)M10 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083260 E(smoDN)845 Enhancer of smoDN 845 http://flybase.org/reports/FBgn0083260 gene - - - E(smoDN)845 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265937 CR44724 - http://flybase.org/reports/FBgn0265937 non_protein_coding_gene - - - CR44724 - CR44724 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052000 CG32000 - http://flybase.org/reports/FBgn0052000 protein_coding_gene "nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR008250, InterPro:IPR023299 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250 calcium-transporting ATPase activity ; GO:0005388 | inferred from biological aspect of ancestor with PANTHER:PTN000643812" cation transport ; GO:0006812 | inferred from electronic annotation with InterPro:IPR006544 cellular calcium ion homeostasis ; GO:0006874 | inferred from biological aspect of ancestor with PANTHER:PTN000643505 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000642960 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000642960 "BcDNA:SD17880, BcDNA:LD19039, BcDNA:LD05303, CG32000" "IPR001757:P-type ATPase, IPR006544:P-type ATPase, subfamily V, IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site, IPR023298:P-type ATPase, transmembrane domain, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N" CG32000 11-Aug-17 DroID_v2017_08 "Drer\atp13a2, Drer\atp13a3" "Scer\PCA1, Scer\YPK9" "Cele\catp-7, Cele\catp-5, Cele\catp-6" "Xtro\atp13a5, Xtro\atp13a3, Xtro\atp13a-like, Xtro\atp13a4" "Mmus\Atp13a3, Mmus\Atp13a5, Mmus\Atp13a4, Mmus\Atp13a2" "Hsap\ATP13A3, Hsap\ATP13A5, Hsap\ATP13A2, Hsap\ATP13A4" viable DRSC17103 IE 1.109331212 2.443208947 3.46895418 -2.100177874 -0.889555555 0.08368044 FBgn0266323 CR44988 - http://flybase.org/reports/FBgn0266323 non_protein_coding_gene - - - CR44988 - CR44988 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033948 CG12863 - http://flybase.org/reports/FBgn0033948 protein_coding_gene "methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR019369 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001594, InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878" - - CG12863 "IPR001878:Zinc finger, CCHC-type, IPR017921:Zinc finger, CTCHY-type, IPR019369:Protein-lysine N-methyltransferase Efm5" CG12863 11-Aug-17 DroID_v2017_08 Drer\zcchc4 - Cele\F33A8.4 Xtro\zcchc4 Mmus\Zcchc4 Hsap\ZCCHC4 FBgn0032598 ChLD3 ChLD3 http://flybase.org/reports/FBgn0032598 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from electronic annotation with InterPro:IPR002509 chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR002509, InterPro:IPR011330 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG17905, ChLD3, DmCDA3, DmChLD3" "IPR002509:NodB homology domain, IPR002557:Chitin binding domain, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG17905 11-Aug-17 DroID_v2017_08 - - "Cele\lgx-1, Cele\F48E3.8" - - - FBgn0015419 l(1)16Ca lethal (1) 16Ca http://flybase.org/reports/FBgn0015419 - gene - - - l(1)16Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037577 CG7443 - http://flybase.org/reports/FBgn0037577 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG7443 - CG7443 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0082331 HM805 HM805 http://flybase.org/reports/FBgn0082331 gene - - - HM805 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060318 l(3)S147402 lethal (3) S147402 http://flybase.org/reports/FBgn0060318 gene - - - "1474/02, l(3)S147402" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0260871 CG42581 - http://flybase.org/reports/FBgn0260871 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42581 - CG42581 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036368 CG10738 - http://flybase.org/reports/FBgn0036368 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 guanylate cyclase activity ; GO:0004383 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | NOT inferred from key residues receptor activity ; GO:0004872 | inferred from sequence or structural similarity guanylate cyclase activity ; GO:0004383 | inferred from sequence or structural similarity with Gyc76C guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 receptor activity ; GO:0004872 | inferred from sequence or structural similarity with Gyc76C cGMP-mediated signaling ; GO:0019934 | inferred from sequence or structural similarity with Gyc76C cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype positive regulation of mitotic cell cycle ; GO:0045931 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | NOT inferred from key residues signal transduction ; GO:0007165 | inferred from sequence or structural similarity negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Gyc76C plasma membrane ; GO:0005886 | inferred from sequence or structural similarity guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "GYC, CG10738" "IPR000719:Protein kinase domain, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001828:Receptor, ligand binding region, IPR011009:Protein kinase-like domain, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase, IPR028082:Periplasmic binding protein-like I, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR011645:Haem NO binding associated" CG10738 11-Aug-17 DroID_v2017_08 "Drer\gc3, Drer\gc2, Drer\si:dkey-37g12.1, Drer\npr3, Drer\si:ch73-139e5.4, Drer\npr1b, Drer\gucy2g, Drer\gucy2c, Drer\ints3, Drer\npr1a, Drer\npr2, Drer\gucy2f" - "Cele\gcy-5, Cele\gcy-2, Cele\gcy-11, Cele\gcy-18, Cele\odr-1, Cele\gcy-6, Cele\gcy-28, Cele\gcy-14, Cele\gcy-8, Cele\gcy-19, Cele\gcy-23, Cele\gcy-21, Cele\gcy-25, Cele\daf-11, Cele\gcy-1, Cele\gcy-7, Cele\gcy-3, Cele\gcy-4, Cele\gcy-13, Cele\gcy-17, Cele\gcy-27, Cele\gcy-29, Cele\Y92H12A.4, Cele\gcy-22, Cele\gcy-12, Cele\gcy-15, Cele\gcy-20, Cele\gcy-9" "Xtro\npr3, Xtro\gucy2c, Xtro\gucy2d, Xtro\npr1, Xtro\gucy2f" "Mmus\Npr2, Mmus\Npr1, Mmus\Gucy2g, Mmus\Gucy2f, Mmus\Gucy2c, Mmus\Npr3, Mmus\Gucy2d, Mmus\Gucy2e, Mmus\Ints3" "Hsap\NPR3, Hsap\NPR2, Hsap\GUCY2F, Hsap\INTS3, Hsap\GUCY2D, Hsap\GUCY2C, Hsap\NPR1" viable FBgn0035923 CG6511 - http://flybase.org/reports/FBgn0035923 protein_coding_gene - - - CG6511 - CG6511 11-Aug-17 DroID_v2017_08 Drer\edrf1 - - Xtro\edrf1 Mmus\Edrf1 Hsap\EDRF1 FBgn0053687 CG33687 - http://flybase.org/reports/FBgn0053687 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33687 IPR010512:Protein of unknown function DUF1091 CG33687 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261932 CG42798 - http://flybase.org/reports/FBgn0261932 protein_coding_gene - - - CG42798 IPR002350:Kazal domain CG42798 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058143 CG40143 - http://flybase.org/reports/FBgn0058143 protein_coding_gene - - - CG40143 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002340 l(3)87Bi lethal (3) 87Bi http://flybase.org/reports/FBgn0002340 - gene - - - "ck21, l(3)ck21, l(3)87Bi" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044814 T:nt1-boss nt1 epitope of boss http://flybase.org/reports/FBgn0044814 engineered_tag - - - "T:nt1-boss, T:boss" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259293 EP-M71 - http://flybase.org/reports/FBgn0259293 gene - - - EP-M71 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing vein" FBgn0065934 l(2)SH0127 lethal (2) SH0127 http://flybase.org/reports/FBgn0065934 gene - - - "l(2)SH0127, l(2)SH2 0127" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037895 CG6723 - http://flybase.org/reports/FBgn0037895 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "CG6723, dSLC5A8" IPR001734:Sodium/solute symporter CG6723 11-Aug-17 DroID_v2017_08 "Drer\slc5a6b, Drer\slc5a3a, Drer\slc5a5, Drer\slc5a1, Drer\slc5a12, Drer\slc5a11, Drer\si:dkeyp-9d4.5, Drer\slc5a8l, Drer\slc5a2, Drer\slc5a8, Drer\slc5a6a, Drer\slc5a9, Drer\LOC568338" Scer\DUR3 "Cele\F52H2.4, Cele\ZK822.5" "Xtro\slc5a12, Xtro\slc5a1.1, Xtro\LOC100488353, Xtro\slc5a5, Xtro\slc5a9, Xtro\slc5a2, Xtro\slc5a11, Xtro\slc5a8" "Mmus\Slc5a10, Mmus\Slc5a8, Mmus\Slc5a6, Mmus\Slc5a11, Mmus\Slc5a2, Mmus\Gm5134, Mmus\Slc5a1, Mmus\Slc5a3, Mmus\Slc5a4b, Mmus\Slc5a9, Mmus\Slc5a4a, Mmus\Slc5a5, Mmus\Slc5a12" "Hsap\SLC5A11, Hsap\SLC5A2, Hsap\SLC5A8, Hsap\SLC5A1, Hsap\SLC5A9, Hsap\SLC5A12, Hsap\SLC5A5, Hsap\SLC5A4, Hsap\SLC5A10, Hsap\SLC5A3, Hsap\SLC5A6" viable FBgn0011156 l(1)Q234 lethal (1) Q234 http://flybase.org/reports/FBgn0011156 FBgn0010210 gene - - - l(1)Q234 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036146 CG14141 - http://flybase.org/reports/FBgn0036146 protein_coding_gene - - - "CT33742, BcDNA:RH33338, CG14141" "IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG14141 11-Aug-17 DroID_v2017_08 "Drer\fgfrl1b, Drer\ptk7a, Drer\fgfrl1a" - "Cele\oig-4, Cele\igcm-4, Cele\oig-1" - Mmus\Fgfrl1 Hsap\FGFRL1 viable FBgn0032703 CG10343 - http://flybase.org/reports/FBgn0032703 protein_coding_gene - - - "anon-WO0118547.123, CG10343" "IPR006575:RWD domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG10343 11-Aug-17 DroID_v2017_08 "Drer\rwdd, Drer\rwdd1" Scer\GIR2 Cele\impt-1 "Xtro\rwdd4, Xtro\rwdd1" "Mmus\Rwdd4a, Mmus\Rwdd1" "Hsap\RWDD4, Hsap\RWDD1" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0013655 ms(2)ry2 ms(2)ry2 http://flybase.org/reports/FBgn0013655 - gene - - - ms(2)ry2 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0259946 Ttd12 TRPL translocation defect 12 http://flybase.org/reports/FBgn0259946 protein_coding_gene - - - Ttd12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011145 l(1)Q221 lethal (1) Q221 http://flybase.org/reports/FBgn0011145 FBgn0010210 gene - - - l(1)Q221 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034045 CG8249 - http://flybase.org/reports/FBgn0034045 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG8249 "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG8249 11-Aug-17 DroID_v2017_08 "Drer\LOC101882338, Drer\slc2a8, Drer\slc2a12, Drer\slc2a13b, Drer\slc2a10, Drer\slc2a6" "Scer\ENB1, Scer\HXT13, Scer\HXT7, Scer\GAL2, Scer\HXT11, Scer\ATR1, Scer\YFL040W, Scer\HXT14, Scer\MPH3, Scer\HXT17, Scer\ITR2, Scer\HXT8, Scer\YMR279C, Scer\HXT9, Scer\GEX2, Scer\VBA5, Scer\VBA3, Scer\VBA4, Scer\SNF3, Scer\SGE1, Scer\HXT16, Scer\HXT4, Scer\HXT1, Scer\GEX1, Scer\MAL11, Scer\HXT10, Scer\HXT5, Scer\HXT2, Scer\ITR1, Scer\MAL31, Scer\HXT3, Scer\VBA1, Scer\AZR1, Scer\HXT15, Scer\STL1, Scer\RGT2, Scer\VBA2, Scer\YDR387C, Scer\HXT6, Scer\MPH2, Scer\YDL199C" Cele\ZK829.9 "Xtro\slc2a6, Xtro\slc2a10, Xtro\slc2a8, Xtro\slc2a12" "Mmus\Slc2a12, Mmus\Slc2a6, Mmus\Slc2a8, Mmus\Slc2a13, Mmus\Slc2a10" "Hsap\SLC2A8, Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SLC2A10, Hsap\SLC2A12" "partially lethal - majority die,some die during pupal stage" FBgn0051354 Hsp70Bbb Hsp70Bbb http://flybase.org/reports/FBgn0051354 protein_coding_gene - response to heat ; GO:0009408 | inferred from mutant phenotype heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "Hsp70, hsp70, HSP70, CG31354, hsp70B, hsp70Bb-prime, CG5834, Hsp70Bb, Hsp70Bbb, Hsp-70, dHsp70, Hsp70B, Dm-hsp70, HSP70Bbb, hsp70bbb, hsp70bBb" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG5834 11-Aug-17 DroID_v2017_08 "Drer\hspa12b, Drer\hsp70.1, Drer\nckap1, Drer\hspa12a, Drer\hspa5, Drer\hsp70.2, Drer\si:dkey-4p15.3, Drer\hsc70, Drer\hspa8, Drer\si:ch211-199o1.2, Drer\hsp70l, Drer\hspa13, Drer\hspa14" "Scer\SSA3, Scer\SSZ1, Scer\SSB1, Scer\SSB2, Scer\SSQ1, Scer\SSA1, Scer\KAR2, Scer\SSA2, Scer\SSA4" "Cele\F44E5.5, Cele\F44E5.4, Cele\hsp-4, Cele\F11F1.1, Cele\hsp-1, Cele\hsp-70, Cele\hsp-3, Cele\gex-3" "Xtro\hsp70, Xtro\hspa1l, Xtro\hspa1a, Xtro\hspa1b, Xtro\hspa13, Xtro\nckap1, Xtro\hspa5, Xtro\hspa2, Xtro\nckap1l, Xtro\hspa12b, Xtro\hspa8, Xtro\hspa14" "Mmus\Hspa13, Mmus\Hspa12a, Mmus\Hspa12b, Mmus\Nckap1, Mmus\Hspa8, Mmus\Hspa14, Mmus\Hspa5, Mmus\Hspa1b, Mmus\Hspa2, Mmus\Hspa1a, Mmus\Hspa1l, Mmus\Nckap1l" "Hsap\HSPA8, Hsap\HSPA12B, Hsap\HSPA12A, Hsap\HSPA1B, Hsap\HSPA14, Hsap\HSPA1L, Hsap\HSPA13, Hsap\NCKAP1L, Hsap\HSPA2, Hsap\HSPA6, Hsap\HSPA5, Hsap\NCKAP1, Hsap\HSPA1A" neuroanatomy defective "Kenyon cell,adult mushroom body" FBgn0003032 pads pads http://flybase.org/reports/FBgn0003032 - gene - - - pads - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0011291 Taf11 TBP-associated factor 11 http://flybase.org/reports/FBgn0011291 - protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000325119 transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf1 inferred from physical interaction with Taf2" positive regulation of protein tetramerization ; GO:1901092 | inferred from direct assay positive regulation of RNA interference ; GO:1900370 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11544 inferred from sequence or structural similarity with SGD:S000004477 transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11544 inferred from sequence or structural similarity with SGD:S000004477 nucleus ; GO:0005634 | inferred from direct assay RISC-loading complex ; GO:0070578 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from direct assay "dTAF[[II]]30beta, TAF30beta, TAF, TFIID, TAF[[II]], TAF[II]30beta, TAF[[II]]30beta, TAF11, dTAFII30beta, d30beta, CG4079, dTAFII30 beta, TFIID 28 beta, dTAF[[II]]30, Taf30beta, dTAFII30, TAF30b, Taf[[II]]30beta, TFIID-p28beta, Taf11, TAF1, G3" "IPR006809:TAFII28-like protein, IPR009072:Histone-fold" CG4079 11-Aug-17 DroID_v2017_08 "Drer\taf11, Drer\snrpb" Scer\TAF11 "Cele\taf-11.2, Cele\snr-2, Cele\taf-11.1, Cele\taf-11.3" "Xtro\snrpb, Xtro\taf11" "Mmus\Snrpn, Mmus\Taf11, Mmus\Snrpb" Hsap\TAF11 "partially lethal - majority die,some die during pupal stage" FBgn0263080 CG43348 - http://flybase.org/reports/FBgn0263080 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43348, CG43180, chr2L_1199311_1199719.0" - CG43348 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060544 l(3)S099006 lethal (3) S099006 http://flybase.org/reports/FBgn0060544 gene - - - "0990/06, l(3)S099006" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0038446 CG14903 - http://flybase.org/reports/FBgn0038446 protein_coding_gene aminoacyl-tRNA hydrolase activity ; GO:0004045 | inferred from electronic annotation with InterPro:IPR002833 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14903 "IPR023476:Peptidyl-tRNA hydrolase II domain, IPR002833:Peptidyl-tRNA hydrolase, PTH2" CG14903 11-Aug-17 DroID_v2017_08 Drer\ptrhd1 Scer\PTH2 Cele\Y94H6A.12 Xtro\ptrhd1 Mmus\Ptrhd1 Hsap\PTRHD1 viable FBgn0032677 CG5790 - http://flybase.org/reports/FBgn0032677 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with SGD:S000002175" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000002175 peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from biological aspect of ancestor with PANTHER:PTN000747050 double-strand break repair via break-induced replication ; GO:0000727 | inferred from biological aspect of ancestor with PANTHER:PTN000747050 protein phosphorylation ; GO:0006468 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 Dbf4-dependent protein kinase complex ; GO:0031431 | inferred from direct assay CG5790 "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG5790 11-Aug-17 DroID_v2017_08 Drer\cdc7 Scer\CDC7 Cele\cdc-7 Xtro\cdc7 Mmus\Cdc7 Hsap\CDC7 "viable,fertile" FBgn0265665 CR44472 - http://flybase.org/reports/FBgn0265665 non_protein_coding_gene - - - CR44472 - CR44472 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037031 CG11456 - http://flybase.org/reports/FBgn0037031 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG11456 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11456 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-266d19.4, Drer\si:dkey-89b17.4, Drer\znf646, Drer\si:dkey-154p10.3, Drer\zbtb37, Drer\znf1016, Drer\zbtb47a, Drer\znf526, Drer\znf990, Drer\znf982, Drer\LOC103910265, Drer\zbtb34, Drer\znf652, Drer\znf1010, Drer\znf1008, Drer\zbtb47b, Drer\zgc:66472, Drer\znf983, Drer\znf1035" Scer\RME1 "Cele\pag-3, Cele\eor-1, Cele\zfp-2, Cele\F58G1.2" Xtro\LOC733928 "Mmus\Zfp953, Mmus\Zfp652, Mmus\Zbtb1, Mmus\Zfp65, Mmus\Zfp771, Mmus\Zfp689, Mmus\Zfp526, Mmus\Zfp459, Mmus\Zfp658, Mmus\Zfp619, Mmus\Zfp759, Mmus\Zfp788, Mmus\Zfp738, Mmus\Zfp458, Mmus\Zbtb34, Mmus\Gm14295, Mmus\Zfp74, Mmus\Zfp324, Mmus\Zbtb37, Mmus\Zfp457, Mmus\Zfp748, Mmus\Zfp282, Mmus\Zfp651, Mmus\Zfp553, Mmus\Zfp764, Mmus\Zfp92" "Hsap\ZNF689, Hsap\ZBTB1, Hsap\ZNF84, Hsap\ZBTB34, Hsap\ZNF264, Hsap\ZNF729, Hsap\ZFP92, Hsap\ZNF107, Hsap\ZBTB37, Hsap\ZNF771, Hsap\ZNF347, Hsap\ZNF764, Hsap\ZNF473, Hsap\ZNF184, Hsap\ZNF850, Hsap\ZNF282, Hsap\ZNF48, Hsap\ZNF324, Hsap\ZNF99, Hsap\ZNF526, Hsap\ZNF497, Hsap\ZNF785, Hsap\ZNF665, Hsap\ZNF91, Hsap\ZBTB47, Hsap\ZNF324B, Hsap\ZNF208, Hsap\ZNF845, Hsap\ZNF805, Hsap\ZNF594, Hsap\ZNF160, Hsap\ZNF569, Hsap\ZNF652" viable FBgn0014060 Su(tor)2-87 Su(tor)2-87 http://flybase.org/reports/FBgn0014060 - gene - - - Su(tor)2-87 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033512 CG12902 - http://flybase.org/reports/FBgn0033512 protein_coding_gene - - - "BcDNA:AT11401, CG12902" - CG12902 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0086346 ALiX ALG-2 interacting protein X http://flybase.org/reports/FBgn0086346 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | contributes_to inferred from sequence or structural similarity with SGD:S000006005 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype positive regulation of JNK cascade ; GO:0046330 | inferred from direct assay exosomal secretion ; GO:1990182 | inferred from mutant phenotype actin filament polymerization ; GO:0030041 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from sequence or structural similarity with SGD:S000006005 male germ-line stem cell asymmetric division ; GO:0048133 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000006005 intercellular bridge ; GO:0045171 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay contractile ring ; GO:0070938 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "ALiX, ALIX, AIP1, DAIP1, Aip1, CG12876, Alix, alix, Snf7" "IPR025304:ALIX V-shaped domain, IPR004328:BRO1 domain" CG12876 11-Aug-17 DroID_v2017_08 "Drer\rhpn2, Drer\ptpn23b, Drer\pdcd6ip, Drer\rhpn1, Drer\ptpn23a" "Scer\RIM20, Scer\BRO1" "Cele\ego-2, Cele\alx-1" "Xtro\rhpn2, Xtro\ptpn23, Xtro\pdcd6ip" "Mmus\Rhpn2, Mmus\Pdcd6ip, Mmus\Ptpn23, Mmus\Rhpn1" "Hsap\PTPN23, Hsap\RHPN2, Hsap\PDCD6IP, Hsap\RHPN1" FBgn0053963 CR33963 - http://flybase.org/reports/FBgn0053963 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GH04518, CR33963" - CR33963 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259201 CG42305 - http://flybase.org/reports/FBgn0259201 protein_coding_gene - - - "CG42305, Dromel_CG17325_FBtr0081102_uORF" - CG42305 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023477 Taldo Transaldolase http://flybase.org/reports/FBgn0023477 FBgn0034934 protein_coding_gene sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity ; GO:0004801 | inferred from electronic annotation with InterPro:IPR004730 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001585, InterPro:IPR018225 pentose-phosphate shunt ; GO:0006098 | inferred from electronic annotation with InterPro:IPR004730" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004730 "154176_at, CT9666, CG2827, tal, Tal, Taldo, TA" "IPR018225:Transaldolase, active site, IPR001585:Transaldolase/Fructose-6-phosphate aldolase, IPR004730:Transaldolase type 1, IPR013785:Aldolase-type TIM barrel" CG2827 11-Aug-17 DroID_v2017_08 Drer\taldo1 "Scer\NQM1, Scer\TAL1" Cele\tald-1 Xtro\taldo1 Mmus\Taldo1 Hsap\TALDO1 "viable,body color defective" mesothoracic tergum FBgn0022702 Cht2 Chitinase 2 http://flybase.org/reports/FBgn0022702 - protein_coding_gene "chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR001579 chitinase activity ; GO:0004568 | non-traceable author statement" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype chitin catabolic process ; GO:0006032 | non-traceable author statement wound healing ; GO:0042060 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype" - "CHT2, DmCHT2, CG2054, Cht2, cht2, DmCht2" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG2054 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-226m16.2, Drer\chia.1, Drer\srl, Drer\chia.5, Drer\chia.2, Drer\ovgp1" Scer\CTS2 "Cele\chil-16, Cele\chil-7, Cele\lmd-4, Cele\chil-3, Cele\chil-13, Cele\chil-9, Cele\lmd-5, Cele\chil-11, Cele\chil-18, Cele\T19H5.6, Cele\chil-21, Cele\chil-17, Cele\chil-19, Cele\chil-12, Cele\chil-22, Cele\cht-2, Cele\cht-3, Cele\chil-24, Cele\cht-1, Cele\chil-4, Cele\cht-4, Cele\chil-20, Cele\chil-6, Cele\chil-2, Cele\chil-25, Cele\chil-1, Cele\chil-15, Cele\chil-5, Cele\chil-23, Cele\chil-8" "Xtro\chia, Xtro\chit1, Xtro\srl, Xtro\LOC548945, Xtro\ctbs" "Mmus\Srl, Mmus\Chil4, Mmus\Chil1, Mmus\Ovgp1, Mmus\Chil3, Mmus\Chia1, Mmus\Chil6, Mmus\Chil5, Mmus\Chit1, Mmus\Ctbs" "Hsap\CTBS, Hsap\OVGP1, Hsap\CHI3L1, Hsap\CHIA, Hsap\SRL, Hsap\CHI3L2, Hsap\CHIT1" "viable,body color defective" "embryonic/larval dorsal trunk,dorsal trunk primordium | embryonic stage 15,mesothoracic tergum" FBgn0259441 EP-87 - http://flybase.org/reports/FBgn0259441 gene - - - EP-87 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0005489 l(1)ts2009 lethal (1) ts2009 http://flybase.org/reports/FBgn0005489 - gene - - - l(1)ts2009 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0041246 Gr32a Gustatory receptor 32a http://flybase.org/reports/FBgn0041246 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement male courtship behavior ; GO:0008049 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr32d, CG14916, Gr32D1, GR32D1, 32D1, 32D.1, GR32D.1, Gr32a, GR32a, Gr32A" IPR013604:7TM chemoreceptor CG14916 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - "courtship behavior defective,male,viable,behavior defective,male fertile,female fertile,semidominant" FBgn0046120 E(To)5 E(To)5 http://flybase.org/reports/FBgn0046120 gene - - - E(To)5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086074 snoRNA:Me18S-A1806 - http://flybase.org/reports/FBgn0086074 snoRNA_gene - - - "snoRNA:Me18S-A1806, Me18S-Am1806, CR34703, Me18S-A1806-RA" - CR34703 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259592 B0540 - http://flybase.org/reports/FBgn0259592 gene - - - B0540 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "macrochaeta,supernumerary" FBgn0021836 l(2)k15617 lethal (2) k15617 http://flybase.net/reports/FBgn0021836.html gene l(2)15617 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0069954 CG41066 - http://flybase.org/reports/FBgn0069954 protein_coding_gene - - - CG41066 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037556 CG9636 - http://flybase.org/reports/FBgn0037556 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of macrophage cytokine production ; GO:0010936 | inferred from sequence or structural similarity with HGNC:28352 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:28352 CG9636 "IPR009060:UBA-like, IPR003892:Ubiquitin system component Cue" CG9636 11-Aug-17 DroID_v2017_08 Drer\cuedc2 - - Xtro\cuedc2 Mmus\Cuedc2 Hsap\CUEDC2 viable FBgn0039408 CG14551 - http://flybase.org/reports/FBgn0039408 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14551 IPR029488:Hemingway/KIAA1430 CG14551 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-83m22.7, Drer\si:ch211-284k5.2" - - Xtro\c17orf105 "Mmus\1700006E09Rik, Mmus\4932443I19Rik" Hsap\C17orf105 viable FBgn0014949 btn buttonless http://flybase.org/reports/FBgn0014949 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from biological aspect of ancestor with PANTHER:PTN001216052" adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN001216052 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001216052 "CG5264, btn/MEOX, 1261/13, btn, BTN" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR020479:Homeobox domain, metazoa" CG5264 11-Aug-17 DroID_v2017_08 "Drer\hoxb5a, Drer\hoxa3a, Drer\hoxb6b, Drer\hoxc6a, Drer\hoxb7a, Drer\mnx1, Drer\hoxb5b, Drer\hoxb1b, Drer\hoxd4a, Drer\hoxc1a, Drer\gsx1, Drer\mnx2a, Drer\hoxa1a, Drer\gbx1, Drer\hoxb1a, Drer\hoxb3a, Drer\hoxb4a, Drer\hoxa2b, Drer\pdx1, Drer\meox2b, Drer\hoxc6b, Drer\meox2a, Drer\hoxc4a, Drer\gsx2, Drer\hoxb2a, Drer\hoxb6a, Drer\meox1, Drer\gbx2, Drer\hoxc8a, Drer\hoxa4a, Drer\hoxb8b, Drer\hoxa5a, Drer\hoxc5a, Drer\hoxc3a, Drer\hoxa9b, Drer\hoxd3a" - "Cele\ceh-12, Cele\mab-5" "Xtro\hoxc8, Xtro\gsx2, Xtro\hoxa2, Xtro\gsx1, Xtro\hoxb7, Xtro\hoxa5, Xtro\hoxb2, Xtro\hoxd8, Xtro\hoxc5, Xtro\mnx1, Xtro\hoxb1, Xtro\hoxb5, Xtro\hoxb6, Xtro\hoxc3, Xtro\hoxb8, Xtro\hoxa3, Xtro\meox2, Xtro\gbx2.1, Xtro\hoxd3, Xtro\hoxc4, Xtro\pdx1, Xtro\gbx2.2, Xtro\hoxb4, Xtro\hoxb3, Xtro\hoxd1, Xtro\hoxa1" "Mmus\Gsx1, Mmus\Pdx1, Mmus\Gbx1, Mmus\Hoxc6, Mmus\Hoxc5, Mmus\Hoxb3, Mmus\Gsx2, Mmus\Hoxa2, Mmus\Hoxa4, Mmus\Mnx1, Mmus\Hoxd4, Mmus\Hoxa7, Mmus\Hoxd1, Mmus\Hoxb1, Mmus\Hoxb6, Mmus\Hoxb2, Mmus\Hoxc8, Mmus\Meox1, Mmus\Hoxb4, Mmus\Meox2, Mmus\Rhox11, Mmus\Hoxb7, Mmus\Hoxd8, Mmus\Hoxb8, Mmus\Hoxd3, Mmus\Hoxa1, Mmus\Rhox10, Mmus\Hoxb5, Mmus\Hoxa5, Mmus\Hoxa3, Mmus\Gbx2, Mmus\Hoxa6, Mmus\Hoxc4" "Hsap\HOXB4, Hsap\HOXA7, Hsap\PDX1, Hsap\HOXC4, Hsap\HOXA5, Hsap\HOXD1, Hsap\HOXB7, Hsap\GSX2, Hsap\HOXC8, Hsap\MNX1, Hsap\HOXD3, Hsap\HOXA3, Hsap\HOXB5, Hsap\HOXB6, Hsap\HOXD8, Hsap\HOXD4, Hsap\GSX1, Hsap\HOXA4, Hsap\MEOX1, Hsap\HOXA6, Hsap\MEOX2, Hsap\HOXC5, Hsap\GBX1, Hsap\HOXA1, Hsap\HOXB8, Hsap\HOXC6, Hsap\HOXA2, Hsap\HOXB2, Hsap\HOXB1, Hsap\GBX2, Hsap\HOXB3" " embryonic stage -- adult stage , embryonic stage | stage >=11 " dorsal neurohemal organ

"viable,partially lethal - majority die,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "macrochaeta,dorsal neurohemal organ,abdominal transverse nerve,transverse nerve & prothoracic segment,transverse nerve & mesothoracic segment,transverse nerve & metathoracic segment" FBgn0260390 CG42516 - http://flybase.org/reports/FBgn0260390 protein_coding_gene - - - "CG42516, Dromel_CG11508_FBtr0088817_uORF" "IPR019481:Transcription factor TFIIIC, tau55-related" CG42516 11-Aug-17 DroID_v2017_08 "Drer\snapc3, Drer\gtf3c6" - - Xtro\gtf3c6 Mmus\Gtf3c6 Hsap\GTF3C6 FBgn0030872 Ucp4A Ucp4A http://flybase.org/reports/FBgn0030872 protein_coding_gene oxidative phosphorylation uncoupler activity ; GO:0017077 | inferred from sequence or structural similarity with UniProtKB:O95847 transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 regulation of mitochondrial membrane potential ; GO:0051881 | inferred from biological aspect of ancestor with PANTHER:PTN001942541 response to cold ; GO:0009409 | inferred from biological aspect of ancestor with PANTHER:PTN001942541 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:O95847 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:O95847 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "dmUCP4a, Ucp4a, DmUCP4A, CG6492, Ucp4A, UCP4A, ucp4a, ucp4A" "IPR018108:Mitochondrial substrate/solute carrier, IPR002030:Mitochondrial brown fat uncoupling protein, IPR023395:Mitochondrial carrier domain" CG6492 11-Aug-17 DroID_v2017_08 "Drer\slc25a11, Drer\slc25a14, Drer\si:ch1073-100f3.2, Drer\slc25a10, Drer\ucp2, Drer\slc25a27, Drer\ucp3, Drer\ucp1, Drer\mrpl12" Scer\DIC1 "Cele\mrpl-12, Cele\slc-25A10, Cele\ucp-4" "Xtro\slc25a10, Xtro\slc25a30, Xtro\slc25a27, Xtro\ucp2, Xtro\ucp1, Xtro\rangrf" "Mmus\Slc25a30, Mmus\Ucp2, Mmus\Ucp1, Mmus\Slc25a11, Mmus\Slc25a27, Mmus\Slc25a14, Mmus\Mrpl12, Mmus\Slc25a10, Mmus\Ucp3" "Hsap\SLC25A27, Hsap\SLC25A14, Hsap\MRPL12, Hsap\SLC25A10, Hsap\UCP2, Hsap\SLC25A30, Hsap\UCP1, Hsap\UCP3, Hsap\SLC25A11" viable FBgn0001667 l(1)EN2 lethal (1) from Eugene Nonautonomous 2 http://flybase.org/reports/FBgn0001667 - gene - - - l(1)EN2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010734 l(3)01029 lethal (3) 01029 http://flybase.org/reports/FBgn0010734 - gene - - - l(3)01029 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065986 iab-4-1.s iab-4-1.s http://flybase.org/reports/FBgn0065986 gene - - - "4-1.s, iab-4-1.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267312 CR45748 - http://flybase.org/reports/FBgn0267312 non_protein_coding_gene - - - CR45748 - CR45748 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030900 Him Holes in muscle http://flybase.org/reports/FBgn0030900 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of muscle organ development ; GO:0048635 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG15064, Him, him" - CG15064 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval muscle system,trichogen cell" FBgn0042177 CG32164 - http://flybase.org/reports/FBgn0042177 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "protein import into nucleus, translocation ; GO:0000060 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 ribosomal protein import into nucleus ; GO:0006610 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN000055427" nuclear periphery ; GO:0034399 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "CG18860, CG18219, CG32164" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG32164 11-Aug-17 DroID_v2017_08 Drer\ipo4 "Scer\KAP123, Scer\PSE1" Cele\imb-3 Xtro\ipo4 "Mmus\Ipo5, Mmus\Ipo4" "Hsap\IPO4, Hsap\IPO5" FBgn0021788 l(2)rQ029 lethal (2) rQ029 http://flybase.org/reports/FBgn0021788 - gene - - - l(2)rQ029 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052453 CG32453 - http://flybase.org/reports/FBgn0052453 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32453 - CG32453 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086079 snoRNA:Me28S-A774a - http://flybase.org/reports/FBgn0086079 snoRNA_gene - - - "snoRNA:Me28S-A774a, Me28S-Am774a, Me28S-A774a(DmU18), CR34708, DmU18adj, Dm_28S.004" - CR34708 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035234 CG12003 - http://flybase.org/reports/FBgn0035234 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12003 - CG12003 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031660 mRpL28 mitochondrial ribosomal protein L28 http://flybase.org/reports/FBgn0031660 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P36525 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q13084 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:P36525 "CG3782, MRP-L28, mRpL28" "IPR034704:L28p-like, IPR026569:Ribosomal protein L28/L24" CG3782 11-Aug-17 DroID_v2017_08 Drer\mrpl28 Scer\MRPL24 Cele\mrpl-28 Xtro\mrpl28 Mmus\Mrpl28 Hsap\MRPL28 "viable,visible" trichogen cell FBgn0067398 Su(2)E Su(2)E http://flybase.org/reports/FBgn0067398 gene - - - Su(2)E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265470 CR44363 - http://flybase.org/reports/FBgn0265470 non_protein_coding_gene - - - CR44363 - CR44363 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060979 l(3)S028614 lethal (3) S028614 http://flybase.org/reports/FBgn0060979 gene - - - "0286/14, l(3)S028614" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031252 CG13690 - http://flybase.org/reports/FBgn0031252 protein_coding_gene "RNA-DNA hybrid ribonuclease activity ; GO:0004523 | inferred from electronic annotation with InterPro:IPR001352, InterPro:IPR004649, InterPro:IPR023160 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001352" RNA metabolic process ; GO:0016070 | inferred from electronic annotation with InterPro:IPR004649 - CG13690 "IPR001352:Ribonuclease HII/HIII, IPR004649:Ribonuclease H2, subunit A, IPR012337:Ribonuclease H-like domain, IPR024567:Ribonuclease HII/HIII domain, IPR023160:Ribonuclease HII, helix-loop-helix cap domain" CG13690 11-Aug-17 DroID_v2017_08 Drer\rnaseh2a Scer\RNH201 Cele\rnh-2 Xtro\rnaseh2a Mmus\Rnaseh2a Hsap\RNASEH2A viable DRSC00359 K -0.025759152 -0.501212145 -0.374430568 0.58839821 2.458803346 0.484176156 FBgn0011209 dbf double fault http://flybase.org/reports/FBgn0011209 - gene - male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "ms(2)04818, dbf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,meiotic cell cycle defective" "Y chromosome loop,spermatid,Nebenkern" FBgn0028509 CenG1A Centaurin gamma 1A http://flybase.org/reports/FBgn0028509 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806 GTPase activator activity ; GO:0005096 | inferred from mutant phenotype GTPase activity ; GO:0003924 | inferred from direct assay GTPase activator activity ; GO:0005096 | inferred from sequence model medium-term memory ; GO:0072375 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from sequence model membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:16921 "ceng1A, BG:DS08220.1, CG7982, CG16867, CG16866, CG31811, cenG1A, CenG1A, cenG1a, cenG, AGAP" "IPR001164:Arf GTPase activating protein, IPR001849:Pleckstrin homology domain, IPR002110:Ankyrin repeat, IPR011993:PH domain-like, IPR020683:Ankyrin repeat-containing domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily" CG31811 11-Aug-17 DroID_v2017_08 "Drer\agap2, Drer\acap1, Drer\asap1b, Drer\agap1, Drer\acap3a, Drer\agap3" "Scer\AGE1, Scer\AGE2" "Cele\cnt-2, Cele\cnt-1" "Xtro\agap2, Xtro\agap3, Xtro\agap1" "Mmus\Acap2, Mmus\Agap3, Mmus\Acap3, Mmus\Acap1, Mmus\Agap1, Mmus\Agap2" "Hsap\AGAP6, Hsap\AGAP11, Hsap\AGAP5, Hsap\AGAP4, Hsap\AGAP3, Hsap\AGAP1, Hsap\ACAP3, Hsap\AGAP2, Hsap\ACAP1, Hsap\AGAP9, Hsap\ACAP2" "viable,fertile,developmental rate defective" FBgn0019844 anon-XXIV anon-XXIV http://flybase.org/reports/FBgn0019844 - gene - - - "XXIV, anon-XXIV" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036861 CG14089 - http://flybase.org/reports/FBgn0036861 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14089 IPR008160:Collagen triple helix repeat CG14089 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0024673 l(2)k00607 lethal (2) k00607 http://flybase.org/reports/FBgn0024673 - gene - - - "6/7, l(2)k00607" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0261790 SmE Small ribonucleoprotein particle protein SmE http://flybase.org/reports/FBgn0261790 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000005685" small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000005685 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG18591, SmE, BcDNA:GM19936, E, snRNPE, dE, E-Sm" "IPR027078:Small nuclear ribonucleoprotein E, IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain" CG18591 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-197g15.6, Drer\snrpe" Scer\SME1 Cele\snr-6 Xtro\snrpe Mmus\Snrpe Hsap\SNRPE FBgn0267618 CR45956 - http://flybase.org/reports/FBgn0267618 non_protein_coding_gene - - - CR45956 - CR45956 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267398 Yeti Yeti http://flybase.org/reports/FBgn0267398 protein_coding_gene kinesin binding ; GO:0019894 | inferred from direct assay meiotic chromosome condensation ; GO:0010032 | inferred from mutant phenotype regulation of histone H3-K9 methylation ; GO:0051570 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype regulation of histone H3-K4 methylation ; GO:0051569 | inferred from mutant phenotype regulation of histone H3-K9 acetylation ; GO:2000615 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "Yeti, CG40218, l(2)41Aa, BEST:GH01620, BcDNA:RE36623, 41Aa, l(2)EMS31, l(2R)EMS-31, GroupI, l(2R)B, YETI, BCNT" "IPR027124:SWR1-complex protein 5/Craniofacial development protein, IPR011421:BCNT-C domain" CG40218 11-Aug-17 DroID_v2017_08 Drer\cfdp1 Scer\SWC5 Cele\F39H11.1 - Mmus\Cfdp1 Hsap\CFDP1 DRSC21138 IEK 2.284178342 0.477119361 1.298167897 -2.48881761 0.900098649 2.235449126 FBgn0259152 Clbn Caliban http://flybase.org/reports/FBgn0259152 protein_coding_gene - positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ; GO:1902167 | inferred from mutant phenotype positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage ; GO:1902231 | inferred from mutant phenotype protein export from nucleus ; GO:0006611 | inferred from mutant phenotype - "Clbn, CG11847" "IPR008532:Domain of unknown function DUF814, IPR021846:Domain of unknown function DUF3441" CG11847 11-Aug-17 DroID_v2017_08 - Scer\RQC2 Cele\Y82E9BR.18 Xtro\nemf "Mmus\Nemf, Mmus\Ermn" "Hsap\ERMN, Hsap\NEMF" FBgn0259640 B2035 - http://flybase.org/reports/FBgn0259640 gene - - - B2035 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0013390 anon-1Ba anon-1Ba http://flybase.org/reports/FBgn0013390 - gene - - - "T7, anon-1Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | 0-12 hr FBgn0051777 CG31777 - http://flybase.org/reports/FBgn0051777 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "BEST:RH19272, CG31777" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG31777 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260109 2L3193 - http://flybase.org/reports/FBgn0260109 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L3193 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0010059 M(2)28 M(2)28 http://flybase.org/reports/FBgn0010059 - gene - - - "M[[28]], M(2)28" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020888 Su(osk)P59 Suppressor of oskar P59 http://flybase.org/reports/FBgn0020888 - gene - - - "P59, Su(osk)P59" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030706 CG8909 - http://flybase.org/reports/FBgn0030706 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" - - "CT25574, CG8909, Dm CG8909" "IPR000033:LDLR class B repeat, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR018097:EGF-like calcium-binding, conserved site, IPR009030:Growth factor receptor cysteine-rich domain, IPR011042:Six-bladed beta-propeller, TolB-like, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR000742:EGF-like domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG8909 11-Aug-17 DroID_v2017_08 "Drer\lrp2a, Drer\lrp1ba, Drer\lrp5, Drer\lrp1bb, Drer\lrp1ab" "Scer\APM2, Scer\APM1, Scer\APM3" "Cele\lrp-1, Cele\lrp-2" Xtro\lrp4 "Mmus\Lrp2, Mmus\Lrp1b, Mmus\Lrp6, Mmus\Lrp5, Mmus\Lrp1, Mmus\Lrp4" "Hsap\LRP5, Hsap\LRP1, Hsap\LRP4, Hsap\LRP1B, Hsap\LRP2, Hsap\LRP6" "lethal,viable" embryonic/larval brain FBgn0263493 CR43482 - http://flybase.org/reports/FBgn0263493 pseudogene_attribute - - - CR43482 - CR43482 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082911 beta-Spec::Actn beta-Spec::Actn http://flybase.org/reports/FBgn0082911 engineered_fusion_gene - - - beta-Spec::Actn - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045761 CHKov1 CHKov1 http://flybase.org/reports/FBgn0045761 protein_coding_gene - - - "CG10618, BcDNA:GH03753, CHKov1, ref(3)D" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like, IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" CG10618 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.10, Cele\F59B1.8" - - - "chemical resistant,viable,visible" "trichogen cell,tormogen cell" FBgn0262837 CG43201 - http://flybase.org/reports/FBgn0262837 protein_coding_gene - - - "CG43201, MIP03715" - CG43201 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267066 CR45510 - http://flybase.org/reports/FBgn0267066 non_protein_coding_gene - - - CR45510 - CR45510 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035398 Cht7 Chitinase 7 http://flybase.org/reports/FBgn0035398 protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR001579 chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 chitin catabolic process ; GO:0006032 | inferred from sequence or structural similarity with UniProtKB:Q13231 wound healing ; GO:0042060 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "Cht7, CG1869, DmCHT7, DmCht7" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR002557:Chitin binding domain, IPR029070:Chitinase insertion domain" CG1869 11-Aug-17 DroID_v2017_08 "Drer\chia.4, Drer\chia.3, Drer\chia.5, Drer\chia.6, Drer\chia.2, Drer\si:ch211-226m16.2, Drer\chia.1, Drer\srl, Drer\ovgp1" Scer\CTS2 "Cele\cht-2, Cele\chil-17, Cele\cht-1, Cele\cht-4" "Xtro\LOC548945, Xtro\ctbs, Xtro\chia, Xtro\chit1, Xtro\srl" "Mmus\Chil6, Mmus\Chil1, Mmus\Chit1, Mmus\Srl, Mmus\Chil5, Mmus\Ovgp1, Mmus\Ctbs, Mmus\Chil4, Mmus\Chil3, Mmus\Chia1" "Hsap\CHIA, Hsap\OVGP1, Hsap\CHI3L2, Hsap\CHI3L1, Hsap\SRL, Hsap\CHIT1" viable FBgn0066340 mmp mampus http://flybase.org/reports/FBgn0066340 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mmp - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0000566 Eip55E Eip55E http://flybase.org/reports/FBgn0000566 - protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from biological aspect of ancestor with PANTHER:PTN000211590 cystathionine gamma-lyase activity ; GO:0004123 | traceable author statement cystathionine gamma-synthase activity ; GO:0003962 | inferred from biological aspect of ancestor with PANTHER:PTN000211591 cysteine biosynthetic process via cystathionine ; GO:0019343 | inferred from biological aspect of ancestor with PANTHER:PTN000211590 glutathione biosynthetic process ; GO:0006750 | inferred from mutant phenotype transsulfuration ; GO:0019346 | inferred from biological aspect of ancestor with PANTHER:PTN000211590 sulfur amino acid metabolic process ; GO:0000096 | non-traceable author statement 'de novo' L-methionine biosynthetic process ; GO:0071266 | inferred from biological aspect of ancestor with PANTHER:PTN000211590 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000211590 "EIP40, Eip40, Eip55BD, CG5345, Eip55E, LD22255" "IPR000277:Cys/Met metabolism, pyridoxal phosphate-dependent enzyme, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase" CG5345 11-Aug-17 DroID_v2017_08 "Drer\cthl, Drer\cth" "Scer\MET17, Scer\YHR112C, Scer\STR3, Scer\STR2, Scer\IRC7, Scer\YLL058W, Scer\YML082W, Scer\CYS3" "Cele\cth-2, Cele\cbl-1, Cele\cth-1" Xtro\cth Mmus\Cth Hsap\CTH " larval stage | third instar , larval stage " " embryonic/larval salivary gland

, lymph gland

, embryonic/larval fat body

" "viable,fertile" FBgn0014031 Spat Serine pyruvate aminotransferase http://flybase.org/reports/FBgn0014031 - protein_coding_gene alanine-glyoxylate transaminase activity ; GO:0008453 | inferred from direct assay serine-pyruvate transaminase activity ; GO:0004760 | inferred from biological aspect of ancestor with PANTHER:PTN000475663 "glycine biosynthetic process, by transamination of glyoxylate ; GO:0019265 | inferred from biological aspect of ancestor with PANTHER:PTN000475663 glyoxylate catabolic process ; GO:0009436 | inferred from direct assay" peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:341 inferred from sequence model lipid particle ; GO:0005811 | inferred from direct assay peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000475663 "Spat, Dm-Spat, spa, CG3926, spat" "IPR000192:Aminotransferase class V domain, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR024169:Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase, IPR020578:Aminotransferase class-V, pyridoxal-phosphate binding site" CG3926 11-Aug-17 DroID_v2017_08 "Drer\agxta, Drer\agxtb" Scer\AGX1 Cele\agxt-1 Xtro\agxt Mmus\Agxt Hsap\AGXT viable FBgn0031637 mxt mextli http://flybase.org/reports/FBgn0031637 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from mutant phenotype eukaryotic initiation factor 4E binding ; GO:0008190 | inferred from physical interaction with eIF4E1 inferred from physical interaction with eIF4E4 inferred from physical interaction with eIF4E7 inferred from physical interaction with eIF4E3 positive regulation of translation ; GO:0045727 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype regulation of formation of translation initiation ternary complex ; GO:1901190 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype RNA cap binding complex ; GO:0034518 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "cg2950, BcDNA:GH06479, mxt, CG2950, Mxt" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR029058:Alpha/Beta hydrolase fold" CG2950 11-Aug-17 DroID_v2017_08 - - Cele\mxt-1 - - - "female semi-fertile,embryonic/larval segmentation phenotype,viable,visible" "embryonic abdominal segment,female germline cell,embryonic thoracic segment,chaeta,supernumerary" FBgn0261446 CG13377 - http://flybase.org/reports/FBgn0261446 protein_coding_gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - "CG13377, BG01596, EG:BACR37P7.9" "IPR016040:NAD(P)-binding domain, IPR002347:Short-chain dehydrogenase/reductase SDR" CG13377 11-Aug-17 DroID_v2017_08 "Drer\zgc:113142, Drer\dhrs9, Drer\rdh1, Drer\rdh5, Drer\hsd11b2, Drer\bdh1, Drer\hsd17b2" - "Cele\dhs-2, Cele\drd-5, Cele\dhs-20, Cele\dhs-16" "Xtro\rdh7, Xtro\rdh5, Xtro\MGC89248, Xtro\hsd17b2, Xtro\dhrs9, Xtro\hsd11b2, Xtro\rdh7.2, Xtro\bdh1, Xtro\hsd17b6, Xtro\LOC100170425, Xtro\LOC100124842, Xtro\rdh16" "Mmus\Dhrs9, Mmus\Rdh9, Mmus\Rdh19, Mmus\Hsd11b2, Mmus\Rdh5, Mmus\Rdh1, Mmus\Hsd17b2, Mmus\BC089597, Mmus\Bdh1, Mmus\Rdh7, Mmus\Hsd17b6, Mmus\Sdr9c7, Mmus\Rdh16" "Hsap\HSD11B2, Hsap\SDR9C7, Hsap\HSD17B6, Hsap\HSD17B2, Hsap\BDH1, Hsap\RDH16, Hsap\RDH5, Hsap\DHRS9" FBgn0036571 Strumpellin Strumpellin http://flybase.org/reports/FBgn0036571 protein_coding_gene - - WASH complex ; GO:0071203 | inferred from direct assay WASH complex ; GO:0071203 | inferred from sequence or structural similarity with UniProtKB:Q12768 "Strumpellin, p118, CG12272, strump" "IPR019393:WASH complex, subunit strumpellin" CG12272 11-Aug-17 DroID_v2017_08 Drer\strumpellin - Cele\T05E7.3 Xtro\kiaa0196 Mmus\E430025E21Rik Hsap\WASHC5 "partially lethal - majority die,visible" mesothoracic tergum FBgn0263511 Vsx1 Visual system homeobox 1 http://flybase.org/reports/FBgn0263511 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:1975" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:1975 phagocytosis ; GO:0006909 | inferred from mutant phenotype optic lobe placode development ; GO:0001748 | inferred from mutant phenotype positive regulation of neural precursor cell proliferation ; GO:2000179 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Vsx1, Vsx-1, Chx1, CG4136, dVsx1, dChx1, DChx1, Dchx1, lincRNA.S8688, DVSX1" "IPR023339:CVC domain, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR004088:K Homology domain, type 1" CG4136 11-Aug-17 DroID_v2017_08 "Drer\alx1, Drer\rx1, Drer\alx3, Drer\vsx2, Drer\rx2, Drer\alx4a, Drer\vsx1, Drer\arxa" Scer\PHO2 "Cele\ceh-16, Cele\dsc-1, Cele\ceh-10" "Xtro\alx4, Xtro\vsx2, Xtro\arx, Xtro\alx1, Xtro\vsx1" "Mmus\Vsx2, Mmus\Vsx1, Mmus\Alx4, Mmus\Alx3, Mmus\Arx" "Hsap\ALX1, Hsap\ARX, Hsap\ALX3, Hsap\VSX2, Hsap\ALX4, Hsap\VSX1" FBgn0010842 l(3)77CDf lethal (3) 77CDf http://flybase.org/reports/FBgn0010842 - gene - - - "l(3)04521, l(3)77CDf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031393 CG15382 - http://flybase.org/reports/FBgn0031393 protein_coding_gene - - - "BcDNA:RE26473, CG15382" - CG15382 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264446 CR43864 - http://flybase.org/reports/FBgn0264446 non_protein_coding_gene - - - CR43864 - CR43864 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026220 l(3)04704b lethal (3) 04704b http://flybase.org/reports/FBgn0026220 - gene - - - "l(3)04704, l(3)04704b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031091 Phf7 PHD finger protein 7 http://flybase.org/reports/FBgn0031091 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 histone binding ; GO:0042393 | inferred from physical interaction with His3 male germ-line sex determination ; GO:0019100 | inferred from mutant phenotype inferred from genetic interaction with otu inferred from genetic interaction with tra polytene chromosome ; GO:0005700 | inferred from direct assay "Phf7, CG9576" "IPR001841:Zinc finger, RING-type, IPR034732:Extended PHD (ePHD) domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9576 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-57f7.7, Drer\g2e3, Drer\phf6, Drer\si:ch211-37e10.1, Drer\phf11" - - "Xtro\phf6, Xtro\g2e3" "Mmus\Phf11d, Mmus\Phf11c, Mmus\Phf7, Mmus\Gm6904, Mmus\Phf11a, Mmus\Phf6, Mmus\Phf11b, Mmus\G2e3" "Hsap\G2E3, Hsap\PHF7, Hsap\PHF11, Hsap\PHF6" "viable,male semi-sterile,female fertile,male fertile,visible" "male germline stem cell,germline clone,spermatocyte,spermatocyte cell spectrosome,trichogen cell" FBgn0031251 CG4213 - http://flybase.org/reports/FBgn0031251 protein_coding_gene - - - CG4213 - CG4213 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" trichogen cell FBgn0264266 CR43766 - http://flybase.org/reports/FBgn0264266 non_protein_coding_gene - - - CR43766 - CR43766 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065706 l(2)SH0612 lethal (2) SH0612 http://flybase.org/reports/FBgn0065706 gene - - - "l(2)SH0612, l(2)SH2 0612" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050501 CG30501 - http://flybase.org/reports/FBgn0050501 protein_coding_gene - - - CG30501 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003593 Su(var)3-2 Suppressor of variegation 3-2 http://flybase.org/reports/FBgn0003593 - gene - - - "Su-var(3)2, Su(var)3-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,viable,fertile" FBgn0259844 Su(Ste):CR42413 Su(Ste):CR42413 http://flybase.org/reports/FBgn0259844 non_protein_coding_gene - - - "Su(Ste):CR42413, CR42413" - CR42413 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040172 l(1)G0347 lethal (1) G0347 http://flybase.org/reports/FBgn0040172 gene - - - l(1)G0347 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,female sterile" FBgn0005045 E(var)36AE Enhancer of variegation 36AE http://flybase.org/reports/FBgn0005045 - gene - - - "E(var)36A-E, E(var)36AE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014873 Pt4 Pt4 http://flybase.org/reports/FBgn0014873 - gene - - - Pt4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023434 l(2)21Bf lethal (2) 21Bf http://flybase.org/reports/FBgn0023434 - gene - - - l(2)21Bf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039754 CG9747 - http://flybase.org/reports/FBgn0039754 protein_coding_gene "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water ; GO:0016717 | inferred from electronic annotation with InterPro:IPR015876" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015876 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804 - CG9747 "IPR005804:Fatty acid desaturase domain, IPR015876:Acyl-CoA desaturase" CG9747 11-Aug-17 DroID_v2017_08 "Drer\scd, Drer\scdb" Scer\OLE1 "Cele\fat-6, Cele\fat-5, Cele\fat-7" Xtro\scd "Mmus\Scd2, Mmus\Scd4, Mmus\Scd3, Mmus\Scd1" "Hsap\SCD, Hsap\SCD5" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267596 CR45934 - http://flybase.org/reports/FBgn0267596 pseudogene_attribute - - - "CR45934, CG40968" - CR45934 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265495 BG01971 - http://flybase.org/reports/FBgn0265495 gene - - - BG01971 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025749 l(3)95Ax lethal (3) 95Ax http://flybase.org/reports/FBgn0025749 - gene - - - l(3)95Ax - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013771 Cyp6a9 Cytochrome P450-6a9 http://flybase.org/reports/FBgn0013771 - protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with Cyp6a2 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "6a9, CYP6A9, P450, P-450, Cyt-P450-rAF4, CG10246, Cyp6a9, CYP6a9" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10246 11-Aug-17 DroID_v2017_08 "Drer\cyp4f3, Drer\cyp4v8, Drer\tbxas1, Drer\cyp4v7, Drer\cyp3c3, Drer\cyp3c4, Drer\cyp3c2, Drer\cyp3a65, Drer\cyp4t8, Drer\cyp3c1" Scer\ERG11 "Cele\cyp-13B1, Cele\cyp-13A8, Cele\cyp-13A5, Cele\cyp-13A4, Cele\cyp-29A3, Cele\cyp-44A1, Cele\cyp-29A2, Cele\cyp-32A1, Cele\cyp-42A1, Cele\cyp-25A6, Cele\cyp-13A7, Cele\cyp-25A2, Cele\cyp-13A1, Cele\cyp-31A2, Cele\cyp-13A2, Cele\cyp-37B1, Cele\cyp-25A1, Cele\cyp-25A4, Cele\cyp-13A6, Cele\cyp-13A3, Cele\cyp-29A4, Cele\cyp-13B2, Cele\cyp-13A12, Cele\cyp-32B1, Cele\cyp-25A3, Cele\cyp-43A1, Cele\cyp-13A11, Cele\cyp-31A3, Cele\cyp-13A10" "Xtro\tbxas1, Xtro\cyp3a4, Xtro\LOC100494419, Xtro\cyp3a5" "Mmus\Cyp3a25, Mmus\Cyp4f13, Mmus\Cyp3a41b, Mmus\Cyp4a32, Mmus\Cyp3a41a, Mmus\Cyp4a12a, Mmus\Cyp4f37, Mmus\Cyp3a59, Mmus\Cyp4a14, Mmus\Cyp4f18, Mmus\Cyp3a44, Mmus\Cyp4f39, Mmus\Cyp4a31, Mmus\Cyp4v3, Mmus\Cyp4f15, Mmus\Cyp20a1, Mmus\Cyp3a13, Mmus\Cyp3a11, Mmus\Cyp4a10, Mmus\Cyp4f16, Mmus\Cyp4a12b, Mmus\Cyp4b1, Mmus\Cyp3a16, Mmus\Cyp4f14, Mmus\Tbxas1, Mmus\Cyp3a57" "Hsap\CYP4F8, Hsap\CYP20A1, Hsap\CYP4F11, Hsap\CYP4V2, Hsap\CYP4A22, Hsap\CYP4X1, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4F22, Hsap\CYP3A43, Hsap\TBXAS1, Hsap\CYP4Z1, Hsap\CYP4A11, Hsap\CYP3A4, Hsap\CYP3A5, Hsap\CYP4F12, Hsap\CYP4F2, Hsap\CYP3A7, Hsap\CYP4F3, Hsap\CYP4B1" adult stage viable FBgn0051313 CG31313 - http://flybase.org/reports/FBgn0051313 protein_coding_gene cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from electronic annotation with InterPro:IPR000010 - - "BcDNA:RH02566, CG31313" "IPR000010:Cystatin domain, IPR018073:Proteinase inhibitor I25, cystatin, conserved site" CG31313 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263335 CR43416 - http://flybase.org/reports/FBgn0263335 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR43416 - CR43416 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036366 CG10133 - http://flybase.org/reports/FBgn0036366 protein_coding_gene - - - CG10133 IPR003347:JmjC domain CG10133 11-Aug-17 DroID_v2017_08 Drer\jmjd7 - - Xtro\jmjd7 Mmus\Jmjd7 "Hsap\JMJD7, Hsap\PLA2G4B, Hsap\JMJD7-PLA2G4B" viable FBgn0261609 eIF2alpha eukaryotic translation initiation factor 2 subunit alpha http://flybase.org/reports/FBgn0261609 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000001734 inferred from genetic interaction with SGD:S000001734 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC:3265 inferred from sequence or structural similarity with SGD:S000003767 ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000063907 translational initiation ; GO:0006413 | inferred from sequence or structural similarity translational initiation ; GO:0006413 | inferred from sequence or structural similarity with HGNC:3265 inferred from sequence or structural similarity with SGD:S000003767 translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD:S000001734 eukaryotic 48S preinitiation complex ; GO:0033290 | inferred from biological aspect of ancestor with PANTHER:PTN000063908 eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity with SGD:S000001734 eukaryotic translation initiation factor 2 complex ; GO:0005850 | inferred from sequence or structural similarity with HGNC:3265 inferred from sequence or structural similarity with SGD:S000003767 eukaryotic translation initiation factor 2 complex ; GO:0005850 | inferred from biological aspect of ancestor with PANTHER:PTN000063908 eukaryotic translation initiation factor 2 complex ; GO:0005850 | inferred from sequence or structural similarity multi-eIF complex ; GO:0043614 | inferred from biological aspect of ancestor with PANTHER:PTN000063908 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:3265 inferred from sequence or structural similarity with SGD:S000003767 ribosome ; GO:0005840 | inferred from biological aspect of ancestor with PANTHER:PTN000063907 cytosol ; GO:0005829 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from biological aspect of ancestor with PANTHER:PTN000063908 "CG9946, P-eIF2alpha, eIF2-alpha, eIF2alpha, M(1)14C, eIF-2 a, eIF-2 alpha, elF2alpha, eIF-2, eIF-2alpha, Eif2alpha, eIF2 alpha, eIF2a, l(1)19-153, l(1)14Cf, M(1)8e3-10, M(1)19-153, IF2A_DROME, deIF2alpha, eiF-2alpha, EIF-2alpha, eIF-2alphaeIF-2alpha" "IPR003029:S1 domain, IPR011488:Translation initiation factor 2, alpha subunit, IPR012340:Nucleic acid-binding, OB-fold, IPR024054:Translation initiation factor 2, alpha subunit, middle domain, IPR024055:Translation initiation factor 2, alpha subunit, C-terminal, IPR022967:RNA-binding domain, S1" CG9946 11-Aug-17 DroID_v2017_08 "Drer\eif2s1a, Drer\eif2s1b, Drer\si:dkeyp-26a9.2" Scer\SUI2 "Cele\C04G2.10, Cele\C26E6.1, Cele\F59E12.15, Cele\H12I13.1, Cele\hasp-2, Cele\Y73B6A.1, Cele\VY10G11R.1, Cele\Y37E3.10, Cele\hasp-1, Cele\Y48B6A.10, Cele\C06E4.5" Xtro\eif2s1 "Mmus\Eif2s1, Mmus\Gsg2" "Hsap\EIF2S1, Hsap\GSG2" embryonic stage&&larval stage DRSC20327 I -1.948948927 -1.591292857 0.849613111 -0.960623177 0.430935888 0.944776251 FBgn0025676 CkIIalpha-i3 CKII-alpha subunit interactor-3 http://flybase.org/reports/FBgn0025676 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CKIIalpha-i3, CkIIalpha-i3, CG3217, CKiialpha-I3" - CG3217 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0028223 l(3)S007302 lethal (3) S007302 http://flybase.org/reports/FBgn0028223 gene - - - "0073/02, l(3)S007302" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038396 CG5013 - http://flybase.org/reports/FBgn0038396 protein_coding_gene protein-lysine N-methyltransferase activity ; GO:0016279 | inferred from sequence or structural similarity with SGD:S000003890 peptidyl-lysine trimethylation ; GO:0018023 | inferred from sequence or structural similarity with SGD:S000003890 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003890 CG5013 "IPR019410:Lysine methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG5013 11-Aug-17 DroID_v2017_08 "Drer\mettl22, Drer\mettl23, Drer\acbd4, Drer\mettl21a, Drer\acbd6, Drer\LOC103909942, Drer\dbi, Drer\zgc:92518, Drer\zgc:172067, Drer\acbd5b, Drer\acbd7, Drer\LOC100149425" "Scer\NNT1, Scer\EFM3, Scer\EFM2, Scer\EFM6" "Cele\maa-1, Cele\C42C1.13, Cele\acbp-6, Cele\acbp-3, Cele\acbp-4, Cele\W06B4.2, Cele\acbp-5, Cele\R08D7.4" "Xtro\acbd5, Xtro\mettl21a, Xtro\eef2kmt, Xtro\mettl21b, Xtro\mettl23, Xtro\acbd6, Xtro\acbd7" "Mmus\Acbd7, Mmus\Acbd5, Mmus\Dbil5, Mmus\Dbi, Mmus\Mettl21e, Mmus\Mettl21c, Mmus\Vcpkmt, Mmus\Mettl21b, Mmus\Acbd6, Mmus\Eef2kmt, Mmus\Acbd4, Mmus\Mettl23, Mmus\Mettl21a, Mmus\Mettl22" "Hsap\METTL21A, Hsap\METTL21B, Hsap\ACBD7, Hsap\ACBD4, Hsap\ACBD6, Hsap\METTL23, Hsap\VCPKMT, Hsap\EEF2KMT, Hsap\METTL22, Hsap\ACBD5, Hsap\DBI, Hsap\METTL21C" viable FBgn0032879 CarT Carcinine transporter http://flybase.org/reports/FBgn0032879 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 carcinine transmembrane transporter activity ; GO:1905131 | inferred from direct assay neurotransmitter transporter activity ; GO:0005326 | inferred from direct assay carcinine import across plasma membrane ; GO:1905130 | inferred from direct assay visual perception ; GO:0007601 | inferred from mutant phenotype neurotransmitter uptake ; GO:0001504 | inferred from direct assay positive phototaxis ; GO:0046956 | inferred from mutant phenotype detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 axon terminus ; GO:0043679 | inferred from direct assay "CarT, CG9317, 38E.10, carT, cart" "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG9317 11-Aug-17 DroID_v2017_08 "Drer\slc22a15, Drer\slc22a17, Drer\slc22a31, Drer\zgc:175176, Drer\slc22a13, Drer\slc22a16, Drer\slc22a23, Drer\zgc:153639, Drer\slc22a4, Drer\LOC100334012, Drer\si:dkey-166k12.1, Drer\slc22a2" "Scer\GIT1, Scer\HXT5, Scer\HXT9, Scer\PHO84, Scer\HXT2" "Cele\K05F1.6, Cele\oct-1, Cele\B0252.3, Cele\oct-2, Cele\Y82E9BR.16, Cele\F45E10.2" "Xtro\slc22a4, Xtro\slc22a5, Xtro\slc22a15.2, Xtro\slc22a13" "Mmus\Slc22a21, Mmus\Slc22a13, Mmus\Slc22a23, Mmus\Slc22a2, Mmus\Slc22a17, Mmus\Slc22a1, Mmus\Slc22a15, Mmus\Slc22a3, Mmus\Slc22a16, Mmus\Slc22a12, Mmus\Slc22a5" "Hsap\SLC22A15, Hsap\SLC22A2, Hsap\SLC22A16, Hsap\SLC22A4, Hsap\SLC22A23, Hsap\SLC22A5, Hsap\SLC22A3, Hsap\SLC22A17, Hsap\SLC22A1, Hsap\SLC22A31" viable FBgn0035644 DNApol-epsilon58 DNA polymerase epsilon 58kD subunit http://flybase.org/reports/FBgn0035644 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007185 DNA-directed DNA polymerase activity ; GO:0003887 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000295225 positive regulation of DNA endoreduplication ; GO:0032877 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of cell cycle process ; GO:0090068 | inferred from mutant phenotype error-prone translesion synthesis ; GO:0042276 | inferred from biological aspect of ancestor with PANTHER:PTN000295225 epsilon DNA polymerase complex ; GO:0008622 | inferred from biological aspect of ancestor with PANTHER:PTN000295225 "CG10489, POLE2, DNApol-epsilon, 10489, Pole2, dpolepsilonp58, DNApol-epsilon58" "IPR007185:DNA polymerase alpha/epsilon, subunit B, IPR016266:DNA polymerase epsilon, subunit B, IPR024639:DNA polymerase epsilon subunit B, N-terminal" CG10489 11-Aug-17 DroID_v2017_08 Drer\pole2 Scer\DPB2 Cele\pole-2 Xtro\pole2 Mmus\Pole2 Hsap\POLE2 "lethal - all die during pupal stage,size defective,mitotic cell cycle defective,endomitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage" "wing disc,ventral thoracic disc,eye disc,embryonic/larval salivary gland,embryonic/larval brain,nucleus,trichogen cell,wing" FBgn0004779 Ccp84Ae Ccp84Ae http://flybase.org/reports/FBgn0004779 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "cc4, CG1330, BG:DS00004.5, Ccp84Ae, Ccp, DmelCcp84Ae" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG1330 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0014251 l(2)60Ad lethal (2) 60Ad http://flybase.org/reports/FBgn0014251 - gene - - - l(2)60Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085640 CG41392 - http://flybase.org/reports/FBgn0085640 protein_coding_gene - - - CG41392 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010558 l(2)03845 lethal (2) 03845 http://flybase.org/reports/FBgn0010558 - gene - - - l(2)03845 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001827 l(1)TS45 lethal (1) TS45 http://flybase.org/reports/FBgn0001827 - gene - - - "l(1)TS-45, l(1)TS45" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0036723 CG12229 - http://flybase.org/reports/FBgn0036723 protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015794 potassium ion binding ; GO:0030955 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015794 pyruvate kinase activity ; GO:0004743 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 pyruvate kinase activity ; GO:0004743 | inferred from sequence or structural similarity with RGD:3336" pyruvate biosynthetic process ; GO:0042866 | inferred from sequence or structural similarity with RGD:3336 glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 glycolytic process ; GO:0006096 | inferred from sequence or structural similarity with RGD:3336 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 cytosol ; GO:0005829 | inferred from sequence or structural similarity with RGD:3336 CG12229 "IPR001697:Pyruvate kinase, IPR015795:Pyruvate kinase, C-terminal" CG12229 11-Aug-17 DroID_v2017_08 "Drer\pkmb, Drer\pkma" "Scer\PYK2, Scer\CDC19" "Cele\pyk-2, Cele\pyk-1" "Xtro\pkm, Xtro\pklr" "Mmus\Pklr, Mmus\Pkm" "Hsap\PKM, Hsap\PKLR" "viable,visible" mesothoracic tergum FBgn0000774 fs(1)A1242 female sterile (1) A1242 http://flybase.org/reports/FBgn0000774 - gene - - - "fs(1)1242, fs(1)A1242" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,lethal,non-rescuable maternal effect,recessive,mitotic cell cycle defective" embryo FBgn0083031 snoRNA:Psi18S-525h snoRNA:Psi18S-525h http://flybase.org/reports/FBgn0083031 snoRNA_gene - - - "snoRNA:Psi18S-525h, psi18S-525h, CR34582" - CR34582 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053792 CG33792 - http://flybase.org/reports/FBgn0053792 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33792 IPR010512:Protein of unknown function DUF1091 CG33792 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000352 cos costa http://flybase.org/reports/FBgn0000352 "FBgn0014275, FBgn0021829" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from biological aspect of ancestor with PANTHER:PTN001537455 microtubule binding ; GO:0008017 | inferred from direct assay motor activity ; GO:0003774 | inferred from sequence or structural similarity with Khc protein kinase binding ; GO:0019901 | inferred from physical interaction with fu smoothened binding ; GO:0005119 | inferred from physical interaction with smo protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P18431 inferred from physical interaction with UniProtKB:P54367 inferred from physical interaction with UniProtKB:P91682 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity transcription factor binding ; GO:0008134 | inferred from physical interaction with ci protein binding ; GO:0005515 | inferred from physical interaction with fu" negative regulation of transcription factor import into nucleus ; GO:0042992 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from direct assay smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from physical interaction with smo negative regulation of sequence-specific DNA binding transcription factor activity ; GO:0043433 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity regulation of proteolysis ; GO:0030162 | non-traceable author statement intraciliary transport ; GO:0042073 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | traceable author statement ovarian follicle cell development ; GO:0030707 | traceable author statement positive regulation of smoothened signaling pathway ; GO:0045880 | traceable author statement regulation of apoptotic process ; GO:0042981 | inferred from genetic interaction with hid cytoplasmic sequestering of transcription factor ; GO:0042994 | inferred from mutant phenotype positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype vesicle membrane ; GO:0012506 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from physical interaction with ci kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with Khc cytoplasm ; GO:0005737 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity Hedgehog signaling complex ; GO:0035301 | inferred from physical interaction with fu inferred from physical interaction with ci "cos2, cos, Cos2, Cos-2, cos-2, CG1708, l(2)161/28, Cos[2], l(2)cos[[2]], COS[2], l(2)k16128, l(2)k16101, COS2, DmCos2, Cos, KIF26A/B, Kif7" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1708 11-Aug-17 DroID_v2017_08 "Drer\LOC100537698, Drer\si:ch73-375g18.1, Drer\kif7, Drer\kif4" Scer\MLP1 Cele\klp-19 "Xtro\kif7, Xtro\kif27" "Mmus\Kif27, Mmus\Kif7, Mmus\Kif4" "Hsap\KIF7, Hsap\KIF27, Hsap\KIF4B, Hsap\KIF4A" embryonic stage && larval stage " embryonic stage | stage 9-12 , embryonic stage , embryonic stage | early , larval stage " "

segment polarity , segment | anterior

, dorsal mesothoracic disc | anterior

" "lethal,hyperplasia,recessive,visible,dominant,cell non-autonomous,somatic clone,wild-type,rescuable maternal effect,germline clone,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,partially,viable" "imaginal disc,wing,female gonopod,dorsal,ventral,genital arch,vulva,epiproct,hypoproct,lateral plate,clasper,hypandrial process,posterior compartment,anterior compartment,eye,cell non-autonomous,somatic clone,adult head,antenna,eye disc,wing disc,embryonic epidermis,germline clone,denticle belt,embryonic/first instar larval cuticle,embryonic segment,wing vein L3,ectopic,polar follicle cell,wing vein,follicle cell,oocyte,sex comb,pupal epidermis,maternal effect,embryonic abdominal segment,border follicle cell,supernumerary,haltere,proximal,wing vein L4,1st posterior cell,anterior,wing blade,egg chamber,germarium,interfollicle cell" FBgn0086757 cbs centrosomin's beautiful sister http://flybase.org/reports/FBgn0086757 protein_coding_gene "ADP-ribosylation factor binding ; GO:0030306 | inferred from physical interaction with Arl1 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab19, Rab6, Rab30 protein homodimerization activity ; GO:0042803 | inferred from sequence model" "protein targeting to Golgi ; GO:0000042 | inferred from electronic annotation with InterPro:IPR000237 centrosome cycle ; GO:0007098 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred by curator from GO:0000138,GO:0017137" perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi trans cisterna ; GO:0000138 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay "cbs, CG4840, dem, dGolgin-97, Cbs" IPR000237:GRIP domain CG4840 11-Aug-17 DroID_v2017_08 "Drer\golga1, Drer\si:ch211-286b5.4" - "Cele\dnc-2, Cele\T01G5.7, Cele\gcc-2, Cele\T01C3.3, Cele\Y45F10B.8, Cele\Y45F10B.9" Xtro\golga1 Mmus\Golga1 Hsap\GOLGA1 "lethal - all die before end of embryonic stage,partially,some die during embryonic stage,viable" "centrosomenos.UTR.THsimVP16,syncytial blastoderm embryo,stage 5 embryo,centrosome | embryonic stage 4nos.UTR.THsimVP16,nucleus | embryonic stage 4nos.UTR.THsimVP16,spindle | embryonic stage 4nos.UTR.THsimVP16,centrosome | embryonic stage 5nos.UTR.THsimVP16,nucleus | embryonic stage 5nos.UTR.THsimVP16,centrosome | supernumerarynos.UTR.THsimVP16" FBgn0266522 Sxl::Soce\Soce-Sxl - http://flybase.org/reports/FBgn0266522 engineered_fusion_gene - - - Sxl::Soce\Soce-Sxl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male limited,partially lethal - majority die,viable" FBgn0085716 CG41596 - http://flybase.org/reports/FBgn0085716 protein_coding_gene - - - CG41596 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065662 l(2)SH0710 lethal (2) SH0710 http://flybase.org/reports/FBgn0065662 gene - - - "l(2)SH0710, l(2)SH2 0710" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260504 Pkc98E::Pkn - http://flybase.org/reports/FBgn0260504 engineered_fusion_gene - - - "Pkc98E::Pkn, Pkn-PKC98E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0265966 CR44753 - http://flybase.org/reports/FBgn0265966 non_protein_coding_gene - - - CR44753 - CR44753 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033581 CG12391 - http://flybase.org/reports/FBgn0033581 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "anon-WO0140519.201, CG12391" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG12391 11-Aug-17 DroID_v2017_08 - Scer\AZF1 Cele\scrt-1 - Mmus\Zfp646 "Hsap\ZBTB47, Hsap\ZNF222, Hsap\ZNF573, Hsap\ZNF248, Hsap\ZNF891, Hsap\ZNF646, Hsap\ZNF317, Hsap\ZNF701, Hsap\ZNF33B, Hsap\ZNF497, Hsap\ZNF79, Hsap\ZNF813" "viable,fertile" FBgn0024553 l(3)L4092 lethal (3) L4092 http://flybase.org/reports/FBgn0024553 - gene - - - l(3)L4092 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "germline cell,male" FBgn0003729 tny thorny http://flybase.org/reports/FBgn0003729 - gene - - - tny - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,visible,viable,poor,eye color defective" "eye,adult thorax & macrochaeta,adult head & macrochaeta,wing,pigment cell" FBgn0002109 l(2)1076 lethal (2) 1076 http://flybase.org/reports/FBgn0002109 - gene - - - l(2)1076 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069135 mcl(3)Z6257 mcl(3)Z6257 http://flybase.org/reports/FBgn0069135 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z6257 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0263392 Tet Ten-Eleven Translocation (TET) family protein http://flybase.org/reports/FBgn0263392 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002857 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002857 oxidative DNA demethylase activity ; GO:0035516 | inferred from direct assay DNA demethylase activity ; GO:0035514 | inferred from mutant phenotype positive regulation of DNA demethylation ; GO:1901537 | inferred from mutant phenotype RNA modification ; GO:0009451 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype oxidative DNA demethylation ; GO:0035511 | inferred from direct assay germ cell development ; GO:0007281 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from mutant phenotype "CG43444, CG2083, CG9973, Idax, Tet, dTet, DMAD" "IPR024779:2OGFeDO, oxygenase domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR002857:Zinc finger, CXXC-type" CG43444 11-Aug-17 DroID_v2017_08 "Drer\tet2, Drer\tet3, Drer\tet1" - - "Xtro\tet3, Xtro\tet2" "Mmus\Tet1, Mmus\Tet3, Mmus\Tet2" "Hsap\TET1, Hsap\TET3, Hsap\TET2" DRSC08550 I -0.378185995 -1.874072846 -0.318890946 0.232404867 -1.227318041 -0.003990655 FBgn0000274 Pka-C2 "Protein kinase, cAMP-dependent, catalytic subunit 2" http://flybase.org/reports/FBgn0000274 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 cAMP-dependent protein kinase activity ; GO:0004691 | inferred from sequence or structural similarity with UniProtKB:P17612 cAMP-dependent protein kinase activity ; GO:0004691 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with UniProtKB:P17612 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein kinase A regulatory subunit binding ; GO:0034237 | inferred from sequence or structural similarity with UniProtKB:P17612" peptidyl-serine phosphorylation ; GO:0018105 | inferred from sequence or structural similarity with UniProtKB:P17612 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleotide-activated protein kinase complex ; GO:0031588 | inferred from sequence or structural similarity with UniProtKB:P17612 cAMP-dependent protein kinase complex ; GO:0005952 | inferred from sequence or structural similarity "PKA C2, PKA, CG12066, DC1, DC1a, CdkB, Pka-C2, PKA-C2" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR000961:AGC-kinase, C-terminal" CG12066 11-Aug-17 DroID_v2017_08 "Drer\LOC556339, Drer\prkacab, Drer\prkg1b, Drer\prkg2, Drer\sgk2b, Drer\prkx, Drer\prkacaa, Drer\prkacba, Drer\prkacbb" "Scer\TPK2, Scer\YPK3, Scer\TPK3, Scer\TPK1" "Cele\F47F2.1, Cele\kin-1" "Xtro\prkx, Xtro\prkg2, Xtro\prkacb, Xtro\prkaca" "Mmus\Prkaca, Mmus\Prkg2, Mmus\Prkg1, Mmus\Prkacb, Mmus\Prkx" "Hsap\PRKG1, Hsap\PRKACB, Hsap\PRKACG, Hsap\PRKX, Hsap\PRKG2, Hsap\PRKACA" embryonic stage&&pupal stage&&adult stage "viable,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0032869 CG17470 - http://flybase.org/reports/FBgn0032869 protein_coding_gene - mesoderm development ; GO:0007498 | inferred from expression pattern - "38D.25, anon-WO0153538.51, anon-WO0140519.68, CG17470" - CG17470 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052378 CG32378 - http://flybase.org/reports/FBgn0052378 protein_coding_gene - - - CG32378 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032229 CG5045 - http://flybase.org/reports/FBgn0032229 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001907 proteolysis ; GO:0006508 | inferred from sequence or structural similarity with UniProtKB:Q16740 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q16740 CG5045 "IPR001907:ATP-dependent Clp protease proteolytic subunit, IPR018215:ClpP, Ser active site, IPR023562:Clp protease proteolytic subunit /Translocation-enhancing protein TepA, IPR029045:ClpP/crotonase-like domain, IPR033135:ClpP, histidine active site" CG5045 11-Aug-17 DroID_v2017_08 Drer\clpp - Cele\clpp-1 Xtro\clpp Mmus\Clpp Hsap\CLPP viable FBgn0065059 snoRNA:660 snoRNA:660 http://flybase.org/reports/FBgn0065059 snoRNA_gene - - - "Dm-660, CR33780, snoRNA:660, chr2R:16453519..16453648" - CR33780 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053391 5SrRNA:CR33391 5SrRNA:CR33391 http://flybase.org/reports/FBgn0053391 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33391, 5SrRNA:CR33391" - CR33391 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261881 l(2)35Be lethal (2) 35Be http://flybase.org/reports/FBgn0261881 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytosol ; GO:0005829 | inferred from direct assay "l(2)35Be, CG4140, l(2)br10, br10, C3, BG:DS00929.2" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG4140 11-Aug-17 DroID_v2017_08 Drer\ankrd49 - Cele\F26F4.12 - Mmus\Ankrd49 Hsap\ANKRD49 FBgn0050363 cola comas sola http://flybase.org/reports/FBgn0050363 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG2149, cola, CG30363" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG30363 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032895 twit target of wit http://flybase.org/reports/FBgn0032895 protein_coding_gene - regulation of neurotransmitter secretion ; GO:0046928 | inferred from mutant phenotype anchored component of plasma membrane ; GO:0046658 | inferred from direct assay "BcDNA:LD40063, twit, CG9335" - CG9335 11-Aug-17 DroID_v2017_08 - - "Cele\K11H12.6, Cele\C15H9.9, Cele\K11H12.7" - - - "viable,fertile,neurophysiology defective" embryonic/larval neuromuscular junction FBgn0260037 33W1 - http://flybase.org/reports/FBgn0260037 gene - - - 33W1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0038646 CG7715 - http://flybase.org/reports/FBgn0038646 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG7715 IPR002557:Chitin binding domain CG7715 11-Aug-17 DroID_v2017_08 - - Cele\F33E11.2 - - - viable FBgn0032487 Ski6 Ski6 http://flybase.org/reports/FBgn0032487 protein_coding_gene - "rRNA 3'-end processing ; GO:0031125 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 defense response to virus ; GO:0051607 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' ; GO:0034427 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype nuclear mRNA surveillance ; GO:0071028 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 polyadenylation-dependent snoRNA 3'-end processing ; GO:0071051 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 U4 snRNA 3'-end processing ; GO:0034475 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 rRNA catabolic process ; GO:0016075 | inferred from biological aspect of ancestor with PANTHER:PTN000237327" nuclear lamina ; GO:0005652 | inferred from direct assay nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000003427 inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay exosome (RNase complex) ; GO:0000178 | inferred from direct assay cytoplasmic exosome (RNase complex) ; GO:0000177 | inferred from biological aspect of ancestor with PANTHER:PTN000237328 cytoplasm ; GO:0005737 | inferred from direct assay nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 "CG15481, dSki6, Ski6, dRrp41, Rrp41" "IPR015847:Exoribonuclease, phosphorolytic domain 2, IPR001247:Exoribonuclease, phosphorolytic domain 1, IPR027408:PNPase/RNase PH domain, IPR020568:Ribosomal protein S5 domain 2-type fold" CG15481 11-Aug-17 DroID_v2017_08 "Drer\exosc6, Drer\exosc4" "Scer\MTR3, Scer\SKI6" "Cele\exos-4.1, Cele\exos-4.2, Cele\tin-9.2" "Xtro\rarg, Xtro\exosc4" Mmus\Exosc4 "Hsap\EXOSC4, Hsap\EXOSC6" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0034602 Lapsyn Leucine-rich repeat activity-regulated protein at synapses http://flybase.org/reports/FBgn0034602 protein_coding_gene - nervous system development ; GO:0007399 | inferred from mutant phenotype presynaptic membrane ; GO:0042734 | colocalizes_with inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "CT35842, CG15658, Lapsyn" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG15658 11-Aug-17 DroID_v2017_08 - - "Cele\lron-1, Cele\iglr-1" Xtro\LOC100485706 Mmus\Lrrc26 Hsap\TLR3 "neuroanatomy defective,learning defective,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,recessive,wild-type,viable" "varicosity | supernumerary | third instar larval stage,neuromuscular junction | third instar larval stage,varicosity | third instar larval stagehow-24B,neuromuscular junction | third instar larval stagehow-24B,NMJ bouton,supernumerary,synapse | third instar larval stage" FBgn0260348 GSd484 - http://flybase.org/reports/FBgn0260348 gene - - - GSd484 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036805 Chmp1 Charged multivesicular body protein 1 http://flybase.org/reports/FBgn0036805 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vacuolar transport ; GO:0007034 | inferred from electronic annotation with InterPro:IPR005024 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from sequence or structural similarity with SGD:S000006435 negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with vn inferred from genetic interaction with aos inferred from genetic interaction with sty inferred from genetic interaction with kek1 late endosome ; GO:0005770 | inferred from sequence or structural similarity with SGD:S000006435 late endosome ; GO:0005770 | inferred from direct assay ESCRT III complex ; GO:0000815 | non-traceable author statement apical part of cell ; GO:0045177 | inferred from direct assay "CHMP1, CG4108, Chmp1, VPS46" IPR005024:Snf7 family CG4108 11-Aug-17 DroID_v2017_08 "Drer\chmp2ba, Drer\chmp1b, Drer\chmp2bb, Drer\chmp1a" Scer\DID2 Cele\did-2 "Xtro\chmp1a, Xtro\chmp1b, Xtro\chmp2b" "Mmus\Chmp1b, Mmus\Chmp1a, Mmus\Chmp2b, Mmus\2610002M06Rik" "Hsap\CHMP2B, Hsap\CHMP1B, Hsap\CHMP1A" FBgn0011283 Obp28a Odorant-binding protein 28a http://flybase.org/reports/FBgn0011283 - protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush pheromone binding ; GO:0005550 | inferred from sequence or structural similarity sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "Obp28a, PBPRP-5, 28a, PBP5, PBPRP5, pbprp5, PB-PRP5, pbprp-5, CG6641, obp28a, Pbprp5, DmelObp28a" IPR006170:Pheromone/general odorant binding protein CG6641 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " antennal segment 3 | medial

, sensillum basiconicum of antennal segment 3

, antennal segment 3 | posterior

" "partially lethal - majority die,some die during pupal stage" DRSC03394 IK 2.061624687 -0.983373749 0.309128604 -0.230023421 -2.098044453 0.427165028 FBgn0040617 CG12515 - http://flybase.org/reports/FBgn0040617 protein_coding_gene - - - CG12515 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266874 CR45335 - http://flybase.org/reports/FBgn0266874 non_protein_coding_gene - - - CR45335 - CR45335 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067642 tortuous-trachea-1 tortuous trachea 1 http://flybase.org/reports/FBgn0067642 gene - "cell adhesion ; GO:0007155 | non-traceable author statement tracheal outgrowth, open tracheal system ; GO:0007426 | non-traceable author statement" - tortuous-trachea-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058119 CG40119 - http://flybase.org/reports/FBgn0058119 protein_coding_gene - - - CG40119 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050185 AIMP3 aaRS-interacting multifunctional protein 3 http://flybase.org/reports/FBgn0050185 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay "CG30185, CG5365, anon-EST:Posey25, AIMP3" "IPR010987:Glutathione S-transferase, C-terminal-like, IPR004046:Glutathione S-transferase, C-terminal" CG30185 11-Aug-17 DroID_v2017_08 "Drer\mars, Drer\gstr, Drer\gstt1b, Drer\gstt2, Drer\eef1g, Drer\vars, Drer\gstt1a, Drer\eef1e1" "Scer\GTT2, Scer\URE2, Scer\GTT1, Scer\CAM1, Scer\YGR201C, Scer\TEF4" Cele\eef-1G "Xtro\gstt1, Xtro\eef1e1, Xtro\eef1g" "Mmus\Gstt2, Mmus\Vars, Mmus\Eef1g, Mmus\Gstt1, Mmus\Gstt3, Mmus\Eef1e1, Mmus\Mars, Mmus\Gstt4" "Hsap\VARS, Hsap\GSTT1, Hsap\GSTT2B, Hsap\EEF1E1, Hsap\GSTT2, Hsap\EEF1G, Hsap\MARS" "viable,fertile" FBgn0041086 zep zeppelin http://flybase.org/reports/FBgn0041086 gene - chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype - zep - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/first instar larval cuticle FBgn0261924 CR42791 - http://flybase.org/reports/FBgn0261924 non_protein_coding_gene - - - "CG42791, CR42791, lincRNA.159" - CR42791 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023219 E(lz)178 E(lz)178 http://flybase.org/reports/FBgn0023219 - gene - - - E(lz)178 - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0037817 Cyp12e1 Cyp12e1 http://flybase.org/reports/FBgn0037817 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "12e1, CG14680, Cyp12e1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG14680 11-Aug-17 DroID_v2017_08 "Drer\cyp11c1, Drer\si:dkey-91i10.3, Drer\cyp24a1, Drer\cyp27a1.4, Drer\zgc:136333, Drer\cyp27a1.2, Drer\cyp11a2, Drer\cyp27c1, Drer\si:ch211-113j14.1, Drer\cyp27b1, Drer\cyp27a7" Scer\DIT2 "Cele\cyp-13A1, Cele\cyp-44A1" "Xtro\LOC100145331, Xtro\cyp11a1, Xtro\cyp27a1, Xtro\cyp27c1, Xtro\cyp24a1, Xtro\cyp27b1" "Mmus\Cyp27b1, Mmus\Cyp11a1, Mmus\Cyp27a1, Mmus\Cyp24a1, Mmus\Cyp11b1, Mmus\Cyp11b2" "Hsap\CYP11A1, Hsap\CYP11B1, Hsap\CYP24A1, Hsap\CYP27A1, Hsap\CYP11B2, Hsap\CYP27B1, Hsap\CYP27C1" viable FBgn0033133 Tsp42Ek Tetraspanin 42Ek http://flybase.org/reports/FBgn0033133 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "CG12841, Dm.Tsp42Ek, Tsp42Ek" "IPR008952:Tetraspanin, EC2 domain, IPR018499:Tetraspanin/Peripherin" CG12841 11-Aug-17 DroID_v2017_08 Drer\cd63 - "Cele\tsp-14, Cele\tsp-2, Cele\tsp-3, Cele\tsp-7, Cele\tsp-1" Xtro\cd63 Mmus\Cd63 Hsap\CD63 "viable,fertile,visible" trichogen cell FBgn0027995 l(3)S125801b lethal (3) S125801b http://flybase.org/reports/FBgn0027995 gene - - - "1258/01, l(3)S125801, l(3)S125801b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0082354 HM30 HM30 http://flybase.org/reports/FBgn0082354 gene - - - HM30 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045044 fs(1)56 female sterile (1) 56 http://flybase.org/reports/FBgn0045044 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)56 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg,dorsal appendage,ovary" FBgn0065572 l(2)SH0959 lethal (2) SH0959 http://flybase.org/reports/FBgn0065572 gene - - - "l(2)SH0959, l(2)SH2 0959" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001022 fs(3)A13 female sterile (3) A13 http://flybase.org/reports/FBgn0001022 - gene - - - fs(3)A13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" female reproductive system FBgn0034958 CG3907 - http://flybase.org/reports/FBgn0034958 protein_coding_gene - - - CG3907 - CG3907 11-Aug-17 DroID_v2017_08 Drer\zgc:77197 - - Xtro\efcab14 Mmus\Efcab14 Hsap\EFCAB14 viable FBgn0264500 CR43899 - http://flybase.org/reports/FBgn0264500 non_protein_coding_gene - - - CR43899 - CR43899 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082689 E(ftz)1427 E(ftz)1427 http://flybase.org/reports/FBgn0082689 gene - - - "1427, E(ftz)1427" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267643 CR45981 - http://flybase.org/reports/FBgn0267643 non_protein_coding_gene - - - CR45981 - CR45981 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065872 l(2)SH0255 lethal (2) SH0255 http://flybase.org/reports/FBgn0065872 gene - - - l(2)SH0255 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038100 Paip2 polyA-binding protein interacting protein 2 http://flybase.org/reports/FBgn0038100 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with pAbp regulation of cell growth ; GO:0001558 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "CG12358, dPaip2, Paip2, paip2, PAIP2" "IPR009818:Ataxin-2, C-terminal" CG12358 11-Aug-17 DroID_v2017_08 Drer\paip2b - - Xtro\paip2b "Mmus\Paip2b, Mmus\Paip2" "Hsap\PAIP2B, Hsap\PAIP2" "visible,cell growth defective,cell size defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing disc,ommatidium,embryonic/larval fat body" FBgn0060539 l(3)S100305 lethal (3) S100305 http://flybase.org/reports/FBgn0060539 gene - - - "1003/05, l(3)S100305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031435 Elba2 Early boundary activity 2 http://flybase.org/reports/FBgn0031435 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | contributes_to inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay "positive regulation of chromatin silencing ; GO:0031937 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay" chromatin silencing complex ; GO:0005677 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Elba2, CG9883, Elba" IPR018379:BEN domain CG9883 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267039 CR45483 - http://flybase.org/reports/FBgn0267039 non_protein_coding_gene - - - CR45483 - CR45483 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065506 l(2)SH1190 lethal (2) SH1190 http://flybase.org/reports/FBgn0065506 gene - - - "l(2)SH1190, l(2)SH2 1190" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005484 l(1)ts1415 lethal (1) ts1415 http://flybase.org/reports/FBgn0005484 - gene - - - l(1)ts1415 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0266815 CR45277 - http://flybase.org/reports/FBgn0266815 non_protein_coding_gene - - - CR45277 - CR45277 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028938 CG16886 - http://flybase.org/reports/FBgn0028938 protein_coding_gene - - - "BG:DS00180.2, CG16886, vajk-1" - CG16886 11-Aug-17 DroID_v2017_08 Drer\si:ch73-366l1.5 - Cele\T26C11.2 - Mmus\Ggn "Hsap\TPRX1, Hsap\GGN" "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0058267 CG40267 - http://flybase.org/reports/FBgn0058267 protein_coding_gene - - - CG40267 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065301 l(2)SH1986 lethal (2) SH1986 http://flybase.org/reports/FBgn0065301 gene - - - "l(2)SH1986, l(2)SH2 1986" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084029 CG41468 - http://flybase.org/reports/FBgn0084029 protein_coding_gene - - - CG41468 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032231 CG5056 - http://flybase.org/reports/FBgn0032231 protein_coding_gene - - - CG5056 - CG5056 11-Aug-17 DroID_v2017_08 Drer\oser1 - Cele\F02E9.5 Xtro\oser1 Mmus\Oser1 Hsap\OSER1 FBgn0038645 CG7714 - http://flybase.org/reports/FBgn0038645 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 lateral inhibition ; GO:0046331 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "anon-EST:ParkEST066, CG7714" IPR002557:Chitin binding domain CG7714 11-Aug-17 DroID_v2017_08 - - Cele\F33E11.2 - - - "viable,visible" "chaeta,mesothoracic tergum" FBgn0065807 l(2)SH0390 lethal (2) SH0390 http://flybase.org/reports/FBgn0065807 gene - - - "l(2)SH0390, l(2)SH2 0390" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038734 CG11453 - http://flybase.org/reports/FBgn0038734 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG11453 "IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site" CG11453 11-Aug-17 DroID_v2017_08 "Drer\acsbg1, Drer\acsf3" Scer\PCS60 "Cele\acs-6, Cele\sur-5, Cele\acs-7, Cele\C32E8.6, Cele\mec-18, Cele\acs-9, Cele\C25G6.3, Cele\acs-14, Cele\acs-10" Xtro\acsf3 "Mmus\Acsbg1, Mmus\Acsf3, Mmus\Aacs" "Hsap\AACS, Hsap\ACSBG1, Hsap\ACSF3" viable FBgn0031710 Vps52 Vacuolar protein sorting 52 http://flybase.org/reports/FBgn0031710 protein_coding_gene syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000367098 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab4 syntaxin binding ; GO:0019905 | inferred from sequence or structural similarity with HGNC:10518 "endocytic recycling ; GO:0032456 | inferred from direct assay lysosomal transport ; GO:0007041 | inferred from biological aspect of ancestor with PANTHER:PTN001021633 endocytic recycling ; GO:0032456 | inferred from sequence or structural similarity with HGNC:10518 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN000367098 Golgi to vacuole transport ; GO:0006896 | inferred from biological aspect of ancestor with PANTHER:PTN000367098" GARP complex ; GO:0000938 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:10518 recycling endosome ; GO:0055037 | inferred from sequence or structural similarity with HGNC:10518 "CG7371, Vps52" IPR007258:Vps52 CG7371 11-Aug-17 DroID_v2017_08 Drer\vps52 Scer\VPS52 Cele\vps-52 Xtro\vps52 Mmus\Vps52 Hsap\VPS52 "viable,visible,planar polarity defective" trichogen cell FBgn0035019 Ir60e Ionotropic receptor 60e http://flybase.org/reports/FBgn0035019 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir60e, DmelIR60e, CG13592, IR60e" - CG13592 11-Aug-17 DroID_v2017_08 "Drer\grik1a, Drer\si:ch211-251b21.1, Drer\grik1b, Drer\si:dkey-183j2.10, Drer\grik4" - "Cele\glr-5, Cele\glr-4" - "Mmus\Grik4, Mmus\Grik1" "Hsap\GRIK1, Hsap\GRIK4" viable FBgn0065212 l(2)SH2259 lethal (2) SH2259 http://flybase.org/reports/FBgn0065212 gene - - - "l(2)SH2259, l(2)SH2 2259" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033814 CG4670 - http://flybase.org/reports/FBgn0033814 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from sequence or structural similarity with HGNC:9756 flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR017905 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017937" integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 "CG4670, DmQSOX1, QSOX1, lincRNA.300" "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017905:ERV/ALR sulfhydryl oxidase domain, IPR017937:Thioredoxin, conserved site" CG4670 11-Aug-17 DroID_v2017_08 "Drer\qsox2, Drer\qsox1" Scer\MPD1 "Cele\T10H10.2, Cele\F47B7.2, Cele\F35G2.1" "Xtro\qsox1, Xtro\qsox2" "Mmus\Qsox1, Mmus\Qsox2" "Hsap\QSOX2, Hsap\QSOX1" viable DRSC06878 K 0.275797445 0.668863621 -0.380386302 0.129656758 0.270278027 -2.036244264 FBgn0039620 wat waterproof http://flybase.org/reports/FBgn0039620 protein_coding_gene long-chain-fatty-acyl-CoA reductase activity ; GO:0050062 | inferred from direct assay fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 "liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype oxidation-reduction process ; GO:0055114 | inferred from direct assay lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "CG1443, wat, Wat" "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG1443 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR2, Hsap\FAR1" "viable,lethal,recessive,fertile" "tracheal branch primordium | embryonic stage 17,tracheal branch primordium,tracheal lumen,taenidium" FBgn0031060 CG14231 - http://flybase.org/reports/FBgn0031060 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR022450 molecular_function ; GO:0003674 | no biological data available tRNA threonylcarbamoyladenosine modification ; GO:0002949 | inferred from biological aspect of ancestor with PANTHER:PTN000200094 EKC/KEOPS complex ; GO:0000408 | inferred from biological aspect of ancestor with PANTHER:PTN000200094 CG14231 "IPR000905:Gcp-like domain, IPR017861:Kae1/TsaD family, IPR022450:tRNA N6-adenosine threonylcarbamoyltransferase, TsaD" CG14231 11-Aug-17 DroID_v2017_08 "Drer\osgep, Drer\osgepl1" "Scer\KAE1, Scer\QRI7" "Cele\Y71H2AM.1, Cele\C01G10.10" Xtro\osgepl1 Mmus\Osgepl1 "Hsap\OSGEPL1, Hsap\OSGEP" FBgn0036745 CG7484 - http://flybase.org/reports/FBgn0036745 protein_coding_gene disulfide oxidoreductase activity ; GO:0015036 | inferred from direct assay cell redox homeostasis ; GO:0045454 | inferred from sequence or structural similarity with MGI:MGI:1927947 nucleus ; GO:0005634 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "BcDNA:SD16138, CG7484, Sep15, Prise 8" "IPR014912:Selenoprotein Sep15/SelM, IPR012336:Thioredoxin-like fold" CG7484 11-Aug-17 DroID_v2017_08 Drer\sep15 - Cele\Y76B12C.3 Xtro\sep15 Mmus\Selenof Hsap\SELENOF viable FBgn0039977 CG17454 - http://flybase.org/reports/FBgn0039977 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:16900 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010304 precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 "SPF30, CG17454" "IPR010304:Survival motor neuron, IPR002999:Tudor domain" CG17454 11-Aug-17 DroID_v2017_08 Drer\smndc1 - Cele\smr-1 Xtro\smndc1 Mmus\Smndc1 Hsap\SMNDC1 FBgn0033697 Cyp6t3 Cyp6t3 http://flybase.org/reports/FBgn0033697 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype regulation of developmental growth ; GO:0048638 | inferred from mutant phenotype" - "6t3, CG8457, Cyp6t3, Cyp6T3" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG8457 11-Aug-17 DroID_v2017_08 "Drer\cyp3c3, Drer\cyp3c1, Drer\cyp3a65, Drer\tbxas1, Drer\cyp3c2, Drer\cyp3c4" Scer\ERG11 "Cele\cyp-13A5, Cele\cyp-25A6, Cele\cyp-25A4, Cele\cyp-13A1, Cele\cyp-13B1, Cele\cyp-44A1, Cele\cyp-13A11, Cele\cyp-13A4, Cele\cyp-25A3, Cele\cyp-25A1, Cele\cyp-13A3, Cele\cyp-43A1, Cele\cyp-13A7, Cele\cyp-13A2, Cele\cyp-13A10, Cele\cyp-25A2, Cele\cyp-13A8, Cele\cyp-13A12, Cele\cyp-13A6, Cele\cyp-13B2" "Xtro\LOC100494419, Xtro\cyp3a5, Xtro\cyp3a4, Xtro\tbxas1" "Mmus\Cyp3a41a, Mmus\Cyp3a16, Mmus\Tbxas1, Mmus\Cyp3a11, Mmus\Cyp3a57, Mmus\Cyp3a25, Mmus\Cyp3a44, Mmus\Cyp3a59, Mmus\Cyp3a13, Mmus\Cyp3a41b" "Hsap\TBXAS1, Hsap\CYP3A43, Hsap\CYP3A7, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A4, Hsap\CYP3A5" "large body,developmental rate defective,visible,viable,feeding behavior defective" "pupa,mouth hooks" FBgn0053731 snmRNA:430:CR33731 snmRNA:430:CR33731 http://flybase.org/reports/FBgn0053731 non_protein_coding_gene - - - "CR33731, snmRNA:430:CR33731" - CR33731 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015470 l(2)44Fe lethal (2) 44Fe http://flybase.org/reports/FBgn0015470 - gene - - - l(2)44Fe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0030356 CR32661 - http://flybase.org/reports/FBgn0030356 non_protein_coding_gene - - - "bs26d09.y1, bs07b04.y1, bs05a04.y1, CG18184, CR32661" - CR32661 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259261 EP-Z - http://flybase.org/reports/FBgn0259261 gene - - - EP-Z - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0060650 l(3)S083502b lethal (3) S083502b http://flybase.org/reports/FBgn0060650 gene - - - "0835/02, l(3)S083502b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005527 l(2)52ACd lethal (2) 52ACd http://flybase.org/reports/FBgn0005527 - gene - - - l(2)52ACd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022101 l(2)k07127 lethal (2) k07127 http://flybase.net/reports/FBgn0022101.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0052137 CG32137 - http://flybase.org/reports/FBgn0052137 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - "CG17366, CG17365, CG32137" - CG32137 11-Aug-17 DroID_v2017_08 "Drer\zgc:153929, Drer\si:dkey-17e16.17, Drer\nfkb1, Drer\zgc:171223, Drer\bicdl1, Drer\si:ch211-235m3.5" Scer\SLK19 - "Xtro\ccdc64b, Xtro\ccdc64" "Mmus\Ccdc64, Mmus\Spdl1, Mmus\Ccdc64b" "Hsap\BICDL1, Hsap\BICDL2, Hsap\SPDL1" "viable,fertile" FBgn0019801 l(1)04 lethal (1) 04 http://flybase.org/reports/FBgn0019801 - gene - - - l(1)04 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031935 CG13793 - http://flybase.org/reports/FBgn0031935 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 CG13793 IPR000175:Sodium:neurotransmitter symporter CG13793 11-Aug-17 DroID_v2017_08 Drer\zgc:158225 - Cele\snf-6 - Mmus\Slc6a7 Hsap\SLC6A7 "viable,fertile" FBgn0259350 C27 - http://flybase.org/reports/FBgn0259350 gene - - - C27 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0034846 CG9863 - http://flybase.org/reports/FBgn0034846 protein_coding_gene ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 protein insertion into mitochondrial membrane from inner side ; GO:0032979 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex IV biogenesis ; GO:0097034 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 inner mitochondrial membrane organization ; GO:0007007 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex III biogenesis ; GO:0097033 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 "BcDNA:AT26616, CG9863" - CG9863 11-Aug-17 DroID_v2017_08 Drer\zgc:123096 Scer\MBA1 Cele\Y62E10A.20 - Mmus\Maip1 Hsap\MAIP1 viable FBgn0066347 l(3)99DEh lethal (3) 99DEh http://flybase.org/reports/FBgn0066347 gene - - - l(3)99DEh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065265 l(2)SH2069 lethal (2) SH2069 http://flybase.org/reports/FBgn0065265 gene - - - "l(2)SH2069, l(2)SH2 2069" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267527 CR45867 - http://flybase.org/reports/FBgn0267527 non_protein_coding_gene - - - CR45867 - CR45867 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044019 S-element\T S-element transposase http://flybase.org/reports/FBgn0044019 transposable_element_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002492, InterPro:IPR009057" "transposition, DNA-mediated ; GO:0006313 | inferred from electronic annotation with InterPro:IPR002492 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR002492" - S-element\T "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR012337:Ribonuclease H-like domain, IPR002492:Transposase, Tc1-like, IPR009057:Homeobox domain-like" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267068 CR45512 - http://flybase.org/reports/FBgn0267068 non_protein_coding_gene - - - CR45512 - CR45512 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040020 MED21 Mediator complex subunit 21 http://flybase.org/reports/FBgn0040020 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KN79 inferred from physical interaction with UniProtKB:Q9GYV9 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from biological aspect of ancestor with PANTHER:PTN000332844 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity transcription coactivator activity ; GO:0003713 | contributes_to inferred from direct assay RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from direct assay "Med21, Trap19, dSRB7, p18, dTRAP19, CG40364, CG17397, MED21" "IPR021384:Mediator complex, subunit Med21" CG17397 11-Aug-17 DroID_v2017_08 Drer\med21 Scer\SRB7 Cele\mdt-21 Xtro\med21 Mmus\Med21 Hsap\MED21 "viable,visible" mesothoracic tergum FBgn0060714 l(3)S070005a lethal (3) S070005a http://flybase.org/reports/FBgn0060714 gene - - - "0700/05, l(3)S070005a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040844 CG12572 - http://flybase.org/reports/FBgn0040844 protein_coding_gene - - - CG12572 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050503 CG30503 - http://flybase.org/reports/FBgn0050503 protein_coding_gene phospholipase A2 activity ; GO:0004623 | inferred from electronic annotation with InterPro:IPR016090 phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090 - "CG1672, BcDNA:RH50933, CG30503" "IPR016090:Phospholipase A2 domain, IPR033113:Phospholipase A2, histidine active site" CG30503 11-Aug-17 DroID_v2017_08 "Drer\LOC101885160, Drer\proca1, Drer\zgc:123275" - "Cele\F36A4.1, Cele\F36A4.5, Cele\F22E5.7, Cele\W04G3.13, Cele\F47C12.7, Cele\W04G3.10, Cele\F47C12.13, Cele\W04G3.7, Cele\F36A4.4, Cele\W04G3.12, Cele\F36A4.3" Xtro\proca1 "Mmus\Proca1, Mmus\Pla2g3" "Hsap\PLA2G3, Hsap\PROCA1" viable FBgn0083233 EP712 EP712 http://flybase.org/reports/FBgn0083233 gene - - - EP712 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015559 unch unchained http://flybase.org/reports/FBgn0015559 - gene molecular_function ; GO:0003674 | no biological data available peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available unch - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "chordotonal organ,lateral" FBgn0263772 CG43689 - http://flybase.org/reports/FBgn0263772 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR002515 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002515" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002515" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR002515 "CG43689, CG43284, CG32778, CG4985, CG32790, CG15376" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR002515:Zinc finger, C2HC-type" CG43689 11-Aug-17 DroID_v2017_08 "Drer\myt1a, Drer\myt1la, Drer\myt1b, Drer\prrc2a, Drer\st18" - Cele\ztf-11 "Xtro\myt1, Xtro\st18" "Mmus\Myt1, Mmus\St18, Mmus\Myt1l" "Hsap\ST18, Hsap\MYT1L, Hsap\MYT1" DRSC18046 E -0.262569822 -0.884354941 -0.308781299 -2.010695163 -1.456967828 -0.922442052 FBgn0262141 CG42867 - http://flybase.org/reports/FBgn0262141 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42867 - CG42867 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267969 CR46247 - http://flybase.org/reports/FBgn0267969 non_protein_coding_gene - - - "lincRNA.944, CR46247" - CR46247 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037139 CG14563 - http://flybase.org/reports/FBgn0037139 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14563 - CG14563 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013483 l(1)3PP4 lethal (1) 3PP4 http://flybase.org/reports/FBgn0013483 - gene - - - l(1)3PP4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic epidermis,germline clone,ventral" FBgn0002470 l(3)SG25 lethal (3) SG25 http://flybase.org/reports/FBgn0002470 FBgn0004721 gene - - - "l(3)dsl-3, l(3)g30L, l(3)dsl3, l(3)A3, l(3)SG25" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0086365 Orct2 Organic cation transporter 2 http://flybase.org/reports/FBgn0086365 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 organic cation transmembrane transporter activity ; GO:0015101 | inferred from sequence or structural similarity with UniProtKB:Q9U539 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 germ-band shortening ; GO:0007390 | inferred from mutant phenotype organic cation transport ; GO:0015695 | inferred from sequence or structural similarity with UniProtKB:Q9U539 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 "orct2, cald, CG13610, Orct2, EP(3)1072, EP1072" "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG13610 11-Aug-17 DroID_v2017_08 "Drer\slc22a6l, Drer\slc22a4, Drer\slc22a15, Drer\si:dkey-119m7.4, Drer\sv2a, Drer\slc22a7a, Drer\sv2bb, Drer\sv2c, Drer\si:dkey-166k12.1, Drer\slc22a2, Drer\slc22a7b.1, Drer\zgc:153639, Drer\svopa, Drer\slc22a16, Drer\slc22a21, Drer\slc22a5" "Scer\HXT9, Scer\HXT2, Scer\PHO84, Scer\YCR023C, Scer\GIT1, Scer\HXT5" "Cele\F45E10.2, Cele\svop-1, Cele\B0361.11, Cele\C06H5.6, Cele\oct-1, Cele\Y82E9BR.16" "Xtro\sv2b, Xtro\sv2a, Xtro\slc22a5, Xtro\svop, Xtro\slc22a4, Xtro\slc22a16, Xtro\slc22a6, Xtro\slc22a15.2, Xtro\slc22a13, Xtro\sv2c" "Mmus\Slc22a7, Mmus\Slc22a6, Mmus\Slc22a12, Mmus\Slc22a16, Mmus\Slc22a22, Mmus\Slc22a1, Mmus\Slc22a13, Mmus\Slc22a4, Mmus\Slc22a3, Mmus\Sv2b, Mmus\Sv2a, Mmus\Sv2c, Mmus\Slc22a21, Mmus\Slc22a8, Mmus\Slc22a5, Mmus\Slc22a20, Mmus\Svop" "Hsap\SLC22A3, Hsap\SLC22A16, Hsap\SLC22A6, Hsap\SLC22A13, Hsap\SVOP, Hsap\SV2A, Hsap\SLC22A20, Hsap\SLC22A4, Hsap\SLC22A5, Hsap\SLC22A11, Hsap\SLC22A8, Hsap\SV2C, Hsap\SV2B, Hsap\SLC22A7, Hsap\SLC22A12" "viable,cell lethalcell lethal,somatic clone,decreased cell size,cell autonomous,lethal - all die before end of embryonic stage,some die during embryonic stage,small body,cold sensitive,developmental rate defective" "germ band,wing margin bristle,somatic clone,chaeta & mesothoracic tergum | somatic clone,wing,eye" FBgn0060441 l(3)S123713 lethal (3) S123713 http://flybase.org/reports/FBgn0060441 gene - - - "1237/13, l(3)S123713" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001263 inaD inactivation no afterpotential D http://flybase.org/reports/FBgn0001263 - protein_coding_gene structural molecule activity ; GO:0005198 | inferred from mutant phenotype structural molecule activity ; GO:0005198 | inferred from direct assay inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P19334 photoreceptor activity ; GO:0009881 | inferred from mutant phenotype calmodulin binding ; GO:0005516 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VL78 myosin binding ; GO:0017022 | traceable author statement myosin III binding ; GO:0031473 | inferred from physical interaction with ninaC protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P13677 receptor signaling complex scaffold activity ; GO:0030159 | traceable author statement phototransduction ; GO:0007602 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype phototransduction ; GO:0007602 | non-traceable author statement deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from physical interaction with trp detection of light stimulus involved in sensory perception ; GO:0050962 | inferred from mutant phenotype protein localization ; GO:0008104 | traceable author statement cellular response to light stimulus ; GO:0071482 | inferred from mutant phenotype inaD signaling complex ; GO:0016027 | traceable author statement rhabdomere ; GO:0016028 | inferred from direct assay inaD signaling complex ; GO:0016027 | inferred from physical interaction with ninaE inferred from physical interaction with trp plasma membrane ; GO:0005886 | inferred from direct assay inaD signaling complex ; GO:0016027 | inferred from physical interaction with trp inferred from physical interaction with inaC inferred from physical interaction with norpA "InaD, INAD, Ina-D, CG3504, inaD" IPR001478:PDZ domain CG3504 11-Aug-17 DroID_v2017_08 "Drer\taar13e, Drer\il16, Drer\inadl, Drer\lnx2b, Drer\lnx1, Drer\pdzd2, Drer\si:dkey-92i15.4, Drer\lnx2a" - "Cele\magi-1, Cele\mpz-1" Xtro\lnx1 "Mmus\Il16, Mmus\Pdzd2, Mmus\Mpdz, Mmus\Patj, Mmus\Lnx1, Mmus\Lnx2" "Hsap\PATJ, Hsap\LNX1, Hsap\MPDZ, Hsap\TJP1, Hsap\IL16, Hsap\LNX2, Hsap\PDZD2" adult stage adult head

adult stage " ocellus

, photoreceptor cell

, rhabdomere

, retina

" "neurophysiology defective,visual behavior defective,wild-type,recessive,auditory perception defective,phototaxis defective,dominant,viable" "eye photoreceptor cell,photoreceptor,photoreceptor cell,retina" FBgn0000427 dec-1 defective chorion 1 http://flybase.org/reports/FBgn0000427 FBgn0000645 protein_coding_gene structural constituent of chorion ; GO:0005213 | inferred from mutant phenotype eggshell chorion assembly ; GO:0007306 | traceable author statement eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype eggshell chorion assembly ; GO:0007306 | non-traceable author statement chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | traceable author statement extracellular region ; GO:0005576 | inferred from direct assay chorion ; GO:0042600 | inferred from direct assay "dec, dec1, fs(1)384, Fc, fs(1)M102, fs(1)1501, Fc1, fs(1)C1, dec[[1]], fs(1)A384, fs(1)M1021, fs(1)A257, fs(1)5, fs(1)14E19, fs(1)14A-114, fs(1)14-963, fs(1)13C-73, fs(1)13C-57, fs(1)13-453, fs(1)12-4860, fs(1)12-403, fs(1)12-3907, fs(1)12-365, fs(1)12-3512, fs(1)12-2514, fs(1)12-1873, fs(1)11-549, Fcp7C, CG2175, dec-1, 39051" "IPR006718:Dec-1 repeat, IPR006719:DEC-1 protein, N-terminal, IPR006720:Dec-1 protein, C-terminal" CG2175 11-Aug-17 DroID_v2017_08 - - - - - - adult stage && oogenesis stage | stage S10 egg chamber

" adult stage && oogenesis stage | stage S10B , adult stage && oogenesis stage | stage S10A " follicle cell

"female sterile,male fertile,dominant,female fertile,electrophoretic variant,wild-type,fertile,female sterile soma-dependent,recessive,viable" "chorion,dorsal appendage,egg,endochorion,vitelline membrane,chorion | somatic clone" FBgn0262214 mir-929 mir-929 stem loop http://flybase.org/reports/FBgn0262214 miRNA_gene - - - "dme-mir-929, miR-929, mir-929, MIR-929, CR42921" - CR42921 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" wing vein FBgn0083234 EP704 EP704 http://flybase.org/reports/FBgn0083234 gene - - - EP704 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013504 l(1)PB8P lethal (1) PB8P http://flybase.org/reports/FBgn0013504 - gene - - - l(1)PB8P - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,recessive,rescuable maternal effect" "embryo,germline clone,embryonic head" FBgn0037538 CG3223 - http://flybase.org/reports/FBgn0037538 protein_coding_gene - - - CG3223 "IPR015940:Ubiquitin-associated domain, IPR015496:Ubiquilin, IPR029071:Ubiquitin-related domain, IPR009060:UBA-like" CG3223 11-Aug-17 DroID_v2017_08 "Drer\ubl7b, Drer\ubl7a" - - Xtro\ubl7 Mmus\Ubl7 Hsap\UBL7 "viable,visible" trichogen cell FBgn0051871 CG31871 - http://flybase.org/reports/FBgn0051871 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - "CG17099, CG17087, CG31871" "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG31871 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH2, Scer\YEH1, Scer\TGL1" "Cele\lipl-4, Cele\lipl-2, Cele\lipl-7, Cele\lipl-5, Cele\lipl-6, Cele\lipl-3, Cele\lipl-8, Cele\lipl-1" Xtro\lipa "Mmus\Lipo3, Mmus\Lipo2, Mmus\Lipo4, Mmus\Lipa, Mmus\Lipn, Mmus\Lipo1, Mmus\Lipk, Mmus\Lipm, Mmus\Lipf" "Hsap\LIPK, Hsap\LIPA, Hsap\LIPN, Hsap\LIPJ, Hsap\LIPM, Hsap\LIPF" "viable,fertile" DRSC02571 K 0.152164934 0.605440329 -1.06891502 -0.424724861 0.198315477 1.586103966 FBgn0034380 Vps51 Vacuolar protein sorting 51 http://flybase.org/reports/FBgn0034380 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN000409559 Golgi vesicle transport ; GO:0048193 | inferred from biological aspect of ancestor with PANTHER:PTN000409559 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000409559 endocytic recycling ; GO:0032456 | inferred from sequence or structural similarity with HGNC:1172 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN000409559" trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000409559 GARP complex ; GO:0000938 | inferred from biological aspect of ancestor with PANTHER:PTN000409559 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000409559 GARP complex ; GO:0000938 | inferred from sequence or structural similarity with HGNC:1172 EARP complex ; GO:1990745 | inferred from biological aspect of ancestor with PANTHER:PTN000409559 "CG15087, Vps51" IPR016159:Cullin repeat-like-containing domain CG15087 11-Aug-17 DroID_v2017_08 Drer\vps51 - Cele\vps-51 Xtro\vps51 Mmus\Vps51 Hsap\VPS51 viable FBgn0020854 fs(2)al female sterile (2) al http://flybase.org/reports/FBgn0020854 - gene - - - "fs(2L)al, fs(2)al" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "embryo,maternal effect,egg,chorion | maternal effect" FBgn0250847 CG14034 - http://flybase.org/reports/FBgn0250847 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 phospholipase activity ; GO:0004620 | inferred from sequence or structural similarity lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR033906 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern phospholipid metabolic process ; GO:0006644 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "CG14034, anon-SAGE:Wang-122" "IPR000734:Triacylglycerol lipase family, IPR033906:Lipase, N-terminal, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG14034 11-Aug-17 DroID_v2017_08 "Drer\lpl, Drer\lipca, Drer\LOC101884800, Drer\lipib, Drer\lipg, Drer\LOC100331214, Drer\lipia, Drer\pla1a" - "Cele\lips-15, Cele\lips-12, Cele\lips-11, Cele\lips-13" "Xtro\lipg, Xtro\lpl" "Mmus\Pla1a, Mmus\Pnliprp2, Mmus\Lipg, Mmus\Pnlip, Mmus\Lipi, Mmus\Lpl, Mmus\Liph, Mmus\Lipc, Mmus\Pnliprp1" "Hsap\PNLIPRP1, Hsap\LIPI, Hsap\PLA1A, Hsap\LIPG, Hsap\PNLIPRP3, Hsap\LIPH, Hsap\LIPC, Hsap\PNLIPRP2, Hsap\LPL, Hsap\PNLIP" FBgn0026433 Grip128 Grip128 http://flybase.org/reports/FBgn0026433 "FBgn0030644, FBtr0074075, FBpp0073891" protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 microtubule minus-end binding ; GO:0051011 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin binding ; GO:0043015 | inferred from direct assay cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype spindle assembly involved in female meiosis II ; GO:0007058 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 interphase microtubule nucleation by interphase microtubule organizing center ; GO:0051415 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 centrosome duplication ; GO:0051298 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 centrosome ; GO:0005813 | inferred from direct assay equatorial microtubule organizing center ; GO:0000923 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin ring complex ; GO:0008274 | inferred from sequence or structural similarity with Grip163 inferred from physical interaction with γTub23C "Dgrip128, Dgrips128, CG9201, grip128, Grip128, GCP5, DGrip128, grip" "IPR007259:Gamma-tubulin complex component protein, IPR015058:Protein of unknown function DUF1878" CG9201 11-Aug-17 DroID_v2017_08 "Drer\zgc:101569, Drer\tlr4bb, Drer\tlr4ba, Drer\tlr8b, Drer\LOC572462, Drer\tlr21, Drer\LOC100332583, Drer\tlr2, Drer\LOC100332783, Drer\tlr1, Drer\tlr20.2, Drer\tlr7, Drer\cd180, Drer\tubgcp6, Drer\tubgcp5, Drer\tlr18, Drer\tlr5a, Drer\LOC100005571, Drer\tlr9, Drer\tlr5b, Drer\tlr3" - Cele\droe-4 "Xtro\tubgcp6, Xtro\tlr7, Xtro\LOC100485164, Xtro\LOC100485201, Xtro\tlr6, Xtro\LOC100485512, Xtro\tlr2, Xtro\LOC100495326, Xtro\LOC100485706, Xtro\tubgcp5, Xtro\tlr5, Xtro\tlr3, Xtro\tlr9" "Mmus\Tlr7, Mmus\Tlr8, Mmus\Tlr2, Mmus\Tlr3, Mmus\Cd180, Mmus\Tubgcp5, Mmus\Tubgcp6, Mmus\Tlr13, Mmus\Tlr12, Mmus\Tlr6, Mmus\Tlr9, Mmus\Tlr4, Mmus\Tlr1, Mmus\Tlr5" "Hsap\TLR8, Hsap\TLR4, Hsap\CD180, Hsap\TLR6, Hsap\TLR9, Hsap\TLR2, Hsap\TLR7, Hsap\TLR3, Hsap\TUBGCP5, Hsap\TLR1, Hsap\TLR5, Hsap\TLR10" "viable,male sterile,female sterile,meiotic cell cycle defective,female,male,mitotic cell cycle defective" "egg,germline clone,Nebenkern,spermatid,S2 cell-line,spindle" FBgn0020846 l(2)108 lethal (2) 108 http://flybase.org/reports/FBgn0020846 - gene - - - "T(2;3)Hin108, l(2)108" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035805 CG7506 - http://flybase.org/reports/FBgn0035805 protein_coding_gene - mitochondrial proton-transporting ATP synthase complex assembly ; GO:0033615 | inferred from sequence or structural similarity with UniProtKB:Q9BUB7 integral component of mitochondrial membrane ; GO:0032592 | inferred from sequence or structural similarity with UniProtKB:Q9BUB7 CG7506 IPR009724:TMEM70 family CG7506 11-Aug-17 DroID_v2017_08 Drer\tmem70 - Cele\F32D8.5 Xtro\tmem70 Mmus\Tmem70 Hsap\TMEM70 FBgn0260868 CG42578 - http://flybase.org/reports/FBgn0260868 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42578 - CG42578 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027232 l(1)G0287 lethal (1) G0287 http://flybase.org/reports/FBgn0027232 - gene - - - l(1)G0287 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,chaeta" FBgn0039848 lox lysyl oxidase-like http://flybase.org/reports/FBgn0039848 protein_coding_gene scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001190 copper ion binding ; GO:0005507 | inferred from direct assay protein-lysine 6-oxidase activity ; GO:0004720 | inferred from sequence or structural similarity with UniProtKB:Q9Y4K0 inferred from direct assay protein-lysine 6-oxidase activity ; GO:0004720 | inferred from direct assay oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001695 cellular protein modification process ; GO:0006464 | inferred from sequence or structural similarity with UniProtKB:Q9Y4K0 cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with UniProtKB:Q9Y4K0 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001190, InterPro:IPR017448" "DmLOXL-1, Dmloxl-1, dmlox-1, CG11335, lox, Lox, LOX" "IPR001190:SRCR domain, IPR001695:Lysyl oxidase, IPR017448:SRCR-like domain" CG11335 11-Aug-17 DroID_v2017_08 "Drer\loxl3b, Drer\loxl3a, Drer\LOC100536376, Drer\LOC100329480, Drer\loxl1, Drer\si:dkey-21h14.9, Drer\loxl5a, Drer\loxl5b, Drer\si:ch73-127m5.1, Drer\loxl2b, Drer\scara5, Drer\si:dkeyp-85e10.1, Drer\si:dkey-14d8.21, Drer\si:ch211-51a6.2, Drer\si:dkey-266f7.1, Drer\si:dkey-21h14.8, Drer\si:ch211-161n3.3, Drer\LOC560447, Drer\prss12, Drer\loxa, Drer\loxl2a, Drer\loxl4, Drer\marco" - - "Xtro\lox, Xtro\prss12, Xtro\loxl1, Xtro\loxl4, Xtro\loxl2, Xtro\cd163, Xtro\LOC100497588" "Mmus\Lox, Mmus\Cd6, Mmus\Loxl4, Mmus\Cd163l1, Mmus\Prss12, Mmus\Scara5, Mmus\Cd5l, Mmus\Cd163, Mmus\Ssc5d, Mmus\Loxl2, Mmus\Ssc4d, Mmus\Loxl3, Mmus\5430419D17Rik, Mmus\Marco, Mmus\5830411N06Rik, Mmus\Loxl1, Mmus\Msr1, Mmus\Dmbt1" "Hsap\CD163, Hsap\PRSS12, Hsap\LOXL1, Hsap\CD5L, Hsap\MARCO, Hsap\LOXL4, Hsap\CD163L1, Hsap\CD6, Hsap\MSR1, Hsap\SSC4D, Hsap\LOX, Hsap\SCARA5, Hsap\SSC5D, Hsap\DMBT1, Hsap\LOXL2, Hsap\LOXL3" embryonic stage -- adult stage organism

viable FBgn0260856 Membrin Membrin http://flybase.org/reports/FBgn0260856 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with SGD:S000004068 SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 "intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 phagocytosis ; GO:0006909 | inferred from mutant phenotype vesicle fusion with Golgi apparatus ; GO:0048280 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype protein targeting to vacuole ; GO:0006623 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype Golgi to vacuole transport ; GO:0006896 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity vesicle fusion ; GO:0006906 | inferred from sequence or structural similarity with SGD:S000004068 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000477446" endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 late endosome membrane ; GO:0031902 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 ER to Golgi transport vesicle membrane ; GO:0012507 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with SGD:S000004068 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 "membrin, CG4780, BcDNA:SD22572, SNARE/membrin, Membrin, Memb" IPR027027:GOSR2/Membrin/Bos1 CG4780 11-Aug-17 DroID_v2017_08 Drer\gosr2 Scer\BOS1 "Cele\memb-1, Cele\memb-2" Xtro\gosr2 Mmus\Gosr2 Hsap\GOSR2 DRSC10448 I 2.999240604 0.176904167 0.223094761 0.11073883 0.305016954 -0.307479355 FBgn0023073 l(1)19Fh lethal (1) 19Fh http://flybase.org/reports/FBgn0023073 - gene - - - "B2/45.4, l(1)19Fh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262897 CR43252 - http://flybase.org/reports/FBgn0262897 non_protein_coding_gene - - - "CG43252, CR43252" - CR43252 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037696 GstZ1 Glutathione S transferase Z1 http://flybase.org/reports/FBgn0037696 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay aromatic amino acid family metabolic process ; GO:0009072 | inferred from electronic annotation with InterPro:IPR005955 glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GstZ1, gstz1, CG9362, GSTZ1" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR005955:Glutathione S-transferases, class Zeta, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold, IPR034333:Glutathione S-transferases, class Zeta , N-terminal, IPR034330:Glutathione S-transferases, class Zeta , C-terminal" CG9362 11-Aug-17 DroID_v2017_08 Drer\gstz1 - "Cele\gst-43, Cele\Y53G8B.1, Cele\gst-42" Xtro\gstz1 Mmus\Gstz1 Hsap\GSTZ1 viable DRSC16478 E 0.07346915 0.783801614 2.116444809 1.416749745 -0.264658984 -0.801114694 FBgn0041833 Eth-AR310 Eth-AR310 http://flybase.org/reports/FBgn0041833 gene - - - "Eth[AR]310, Eth-AR310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0031762 CG9098 - http://flybase.org/reports/FBgn0031762 protein_coding_gene guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from electronic annotation with InterPro:IPR001895 SH3/SH2 adaptor activity ; GO:0005070 | inferred from biological aspect of ancestor with PANTHER:PTN001023064 Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | inferred from sequence model small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001895 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001023064 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from sequence model cellular_component ; GO:0005575 | no biological data available CG9098 "IPR000980:SH2 domain, IPR001660:Sterile alpha motif domain, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR013761:Sterile alpha motif/pointed domain, IPR023578:Ras guanine nucleotide exchange factor domain" CG9098 11-Aug-17 DroID_v2017_08 "Drer\sh2d3a, Drer\sh2d3cb, Drer\bcar3, Drer\sh2d3ca" - Cele\F23C8.7 "Xtro\bcar3, Xtro\sh2d3c" "Mmus\Bcar3, Mmus\Sh2d3c" "Hsap\SH2D3A, Hsap\BCAR3, Hsap\SH2D3C" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0029725 CG2871 - http://flybase.org/reports/FBgn0029725 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2871 - CG2871 11-Aug-17 DroID_v2017_08 "Drer\LOC559991, Drer\map1aa, Drer\si:ch211-116m6.3, Drer\rrbp1a, Drer\ktn1, Drer\map1ab, Drer\si:ch211-160d20.5, Drer\map1sa, Drer\map1b, Drer\map1sb" - "Cele\H39E23.3, Cele\maph-1.3, Cele\maph-1.1, Cele\arrd-27, Cele\H11L12.1, Cele\maph-1.2, Cele\D1086.9" "Xtro\ktn1, Xtro\rrbp1, Xtro\map1b" "Mmus\Map1a, Mmus\Map1s, Mmus\Rrbp1, Mmus\Map1b, Mmus\Ktn1" "Hsap\MAP1B, Hsap\KTN1, Hsap\MAP1S, Hsap\MAP1A, Hsap\RRBP1, Hsap\FAM47A, Hsap\FAM47C" FBgn0067880 Mod(Prat:bw)2-3 Mod(Prat:bw)2-3 http://flybase.org/reports/FBgn0067880 gene - - - "Mod-2-3, Mod(Prat:bw)2-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,dominant,lethal,recessive" FBgn0065544 l(2)SH1054 lethal (2) SH1054 http://flybase.org/reports/FBgn0065544 gene - - - "l(2)SH1054, l(2)SH2 1054" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020544 l(1)18DEa lethal (1) 18DEa http://flybase.org/reports/FBgn0020544 - gene - - - l(1)18DEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0039172 Spase22-23 Spase 22/23-subunit http://flybase.org/reports/FBgn0039172 protein_coding_gene peptidase activity ; GO:0008233 | inferred from biological aspect of ancestor with PANTHER:PTN000301433 protein targeting to ER ; GO:0045047 | inferred from biological aspect of ancestor with PANTHER:PTN000301433 signal peptide processing ; GO:0006465 | inferred from biological aspect of ancestor with PANTHER:PTN000301433 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007653 signal peptidase complex ; GO:0005787 | inferred from biological aspect of ancestor with PANTHER:PTN000301433 "CG5677, Spase22/23, Spase22-23" IPR007653:Signal peptidase complex subunit 3 CG5677 11-Aug-17 DroID_v2017_08 "Drer\auh, Drer\echdc2, Drer\spcs3" Scer\SPC3 "Cele\K12H4.4, Cele\ech-5" "Xtro\echdc2, Xtro\spcs3, Xtro\auh" "Mmus\Spcs3, Mmus\Echdc2, Mmus\Arxes1, Mmus\Auh, Mmus\Arxes2" "Hsap\ECHDC2, Hsap\SPCS3" "lethal,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0025337 anon-58Ff anon-58Ff http://flybase.org/reports/FBgn0025337 - gene - - - "5-1, anon-58Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011574 Csr Chaser http://flybase.org/reports/FBgn0011574 - gene molecular_function ; GO:0003674 | no biological data available larval foraging behavior ; GO:0035177 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Csr - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,dominant,viable" FBgn0038482 CG4053 - http://flybase.org/reports/FBgn0038482 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP185, CG4053" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG4053 11-Aug-17 DroID_v2017_08 - - "Cele\try-1, Cele\svh-1" - "Mmus\Klk14, Mmus\Egfbp2, Mmus\Prss55" "Hsap\KLK6, Hsap\KLK14" FBgn0082642 Outburst Outburst http://flybase.org/reports/FBgn0082642 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "Outburst, Ort" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263664 CR43655 - http://flybase.org/reports/FBgn0263664 non_protein_coding_gene - - - CR43655 - CR43655 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000522 dwu dwarf unexpanded http://flybase.org/reports/FBgn0000522 - gene - - - dwu - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,poor,male fertile,reduced" "wing,adult abdomen,adult thorax" FBgn0261842 pre-mod(mdg4)-AE - http://flybase.org/reports/FBgn0261842 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-AE, CG42774, RAE" "IPR007588:Zinc finger, FLYWCH-type" CG42774 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035708 CG8398 - http://flybase.org/reports/FBgn0035708 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 neurogenesis ; GO:0022008 | inferred from biological aspect of ancestor with PANTHER:PTN001229949 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001229949 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "anon-EST:Posey31, CG8398" IPR011705:BTB/Kelch-associated CG8398 11-Aug-17 DroID_v2017_08 "Drer\btbd6b, Drer\btbd2, Drer\btbd17b, Drer\btbd3a, Drer\btbd3b, Drer\btbd6a" Scer\YIL001W Cele\tag-30 "Xtro\btbd1, Xtro\btbd6, Xtro\btbd3, Xtro\btbd2" "Mmus\Btbd3, Mmus\Btbd17, Mmus\Btbd1, Mmus\Btbd6, Mmus\Btbd2" "Hsap\BTBD2, Hsap\BTBD6, Hsap\BTBD3, Hsap\BTBD17, Hsap\BTBD1" viable FBgn0263904 l(3)CL62 - http://flybase.org/reports/FBgn0263904 gene - - - l(3)CL62 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0259575 GG01457 - http://flybase.org/reports/FBgn0259575 gene - - - GG01457 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,arista,unguis,tarsal segment" FBgn0046698 Pp1-Y2 "Protein phosphatase 1, Y-linked 2" http://flybase.org/reports/FBgn0046698 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with HGNC:9283 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:9283 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:9283 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:9283 "Pp1-Y2, DmPp1-Y2, CG40448, Pp1Y2" "IPR029052:Metallo-dependent phosphatase-like, IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR031675:Serine-threonine protein phosphatase, N-terminal" CG40448 11-Aug-17 DroID_v2017_08 "Drer\ppp1cb, Drer\ppp1caa, Drer\ppp1cbl, Drer\ppp1cc" "Scer\PPZ1, Scer\PPZ2, Scer\PPQ1, Scer\GLC7" "Cele\pph-1, Cele\Y71G12B.30, Cele\F52H3.6, Cele\gsp-2, Cele\gsp-4, Cele\C30A5.4, Cele\C06A1.3, Cele\F22D6.9, Cele\Y69E1A.4, Cele\T25B9.2, Cele\F58G1.3, Cele\R13A5.11, Cele\F23B12.1, Cele\gsp-1, Cele\ZK938.1, Cele\C34D4.2" "Xtro\ppp1cc, Xtro\ppp1cb" "Mmus\Ppp1ca, Mmus\Ppp1cc, Mmus\Ppp1cb" "Hsap\PPP1CC, Hsap\PPP1CA, Hsap\PPP1CB" FBgn0037200 CG11109 - http://flybase.org/reports/FBgn0037200 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002478, InterPro:IPR018314 RNA methyltransferase activity ; GO:0008173 | inferred from biological aspect of ancestor with PANTHER:PTN000515868 S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from biological aspect of ancestor with PANTHER:PTN000515868" RNA methylation ; GO:0001510 | inferred from biological aspect of ancestor with PANTHER:PTN000515868 - "CT31087, CG11109" "IPR001678:SAM-dependent methyltransferase RsmB/NOP2-type, IPR002478:PUA domain, IPR018314:Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site, IPR015947:PUA-like domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR023267:RNA (C5-cytosine) methyltransferase" CG11109 11-Aug-17 DroID_v2017_08 "Drer\nop2, Drer\nsun6" Scer\NOP2 - "Xtro\nop2, Xtro\nsun6" "Mmus\Nop2, Mmus\Nsun6" "Hsap\NOP2, Hsap\NSUN6" viable FBgn0033434 CG1902 - http://flybase.org/reports/FBgn0033434 protein_coding_gene - - - CG1902 "IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG1902 11-Aug-17 DroID_v2017_08 "Drer\sec14l8, Drer\rlbp1b, Drer\ttpa, Drer\ttpal, Drer\sec14l7, Drer\clvs2, Drer\rlbp1a" "Scer\YKL091C, Scer\SFH5, Scer\SEC14" - "Xtro\sec14l3, Xtro\clvs2, Xtro\rlbp1, Xtro\ttpa, Xtro\sec14l5, Xtro\sec14l1, Xtro\ttpal, Xtro\mospd2, Xtro\clvs1" "Mmus\Sec14l3, Mmus\Sec14l5, Mmus\Sec14l2, Mmus\Clvs2, Mmus\Clvs1, Mmus\Rlbp1, Mmus\Ttpal, Mmus\Ttpa, Mmus\Sec14l1, Mmus\Sec14l4" "Hsap\RLBP1, Hsap\SEC14L4, Hsap\SEC14L1, Hsap\SEC14L6, Hsap\TTPA, Hsap\CLVS1, Hsap\CLVS2, Hsap\TTPAL, Hsap\SEC14L3, Hsap\SEC14L2, Hsap\SEC14L5" "viable,fertile" FBgn0000819 fs(1)K1134 female sterile (1) K1134 http://flybase.org/reports/FBgn0000819 - gene - - - fs(1)K1134 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "fat body,follicle cell" FBgn0044094 E(rst)D184 E(rst)D184 http://flybase.org/reports/FBgn0044094 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D184, E(rst)D184" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0052086 CG32086 - http://flybase.org/reports/FBgn0052086 protein_coding_gene - - - "CG6100, CG32086" - CG32086 11-Aug-17 DroID_v2017_08 Drer\efhb - - - Mmus\Efhb Hsap\EFHB viable FBgn0040861 CG15722 - http://flybase.org/reports/FBgn0040861 protein_coding_gene - - - CG15722 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267234 CR45674 - http://flybase.org/reports/FBgn0267234 non_protein_coding_gene - - - CR45674 - CR45674 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026650 l(2)50F7 lethal (2) 50F7 http://flybase.org/reports/FBgn0026650 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)50F7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0032642 CG5110 - http://flybase.org/reports/FBgn0032642 protein_coding_gene protein complex scaffold ; GO:0032947 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q9UHA4 guanyl-nucleotide exchange factor activity ; GO:0005085 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q9UHA4 positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype cellular response to amino acid stimulus ; GO:0071230 | inferred from sequence or structural similarity with UniProtKB:Q9UHA4 cellular response to amino acid stimulus ; GO:0071230 | inferred from mutant phenotype cellular protein localization ; GO:0034613 | inferred from sequence or structural similarity with UniProtKB:Q9UHA4 Ragulator complex ; GO:0071986 | inferred from sequence or structural similarity with UniProtKB:Q9UHA4 "MP1, BcDNA:RE09173, CG5110, dMP1" IPR015019:Ragulator complex protein LAMTOR3 CG5110 11-Aug-17 DroID_v2017_08 Drer\lamtor3 - Cele\lmtr-3 Xtro\lamtor3-like Mmus\Lamtor3 Hsap\LAMTOR3 "visible,heat sensitive,viable" "wing vein,ectopic,wing,heat sensitive" FBgn0028549 AT76-2A AT76-2A http://flybase.org/reports/FBgn0028549 gene - - - "AT76, 2A, AT76-2A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013384 acj8 abnormal-chemosensory-jump-8 http://flybase.org/reports/FBgn0013384 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,recessive" FBgn0263589 CR43614 - http://flybase.org/reports/FBgn0263589 non_protein_coding_gene - - - CR43614 - CR43614 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052361 tRNA:Leu-CAG-1-5 transfer RNA:Leucine-CAG 1-5 http://flybase.org/reports/FBgn0052361 tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "CR32361, AE002602.trna7-LeuCAG, tRNA[Leu][[2]], tRNA:leu2:66B, tRNA:L2:66B, tRNA:L:CAG:AE002602-c, chr3L.trna41-LeuCAG, tRNA-Leu-CAG-1-5, tRNA:Leu-CAG-1-5, tRNA:CR32361, CUG" - CR32361 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040574 CG5115 - http://flybase.org/reports/FBgn0040574 protein_coding_gene - - - CG5115 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001857 l(1)TW1 lethal (1) TW1 http://flybase.org/reports/FBgn0001857 - gene - - - l(1)TW1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal - all die before end of larval stage,cold sensitive,some die during larval stage" FBgn0010332 oho31 overgrown hematopoietic organs-31 http://flybase.org/reports/FBgn0010332 FBgn0014274 gene - protein import into nucleus ; GO:0006606 | non-traceable author statement - "oho-31, l(2)k14401, l(2)144/1, l(2)oho31, oho31" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,hyperplasia,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,embryonic/larval lymph gland,embryonic/larval hemolymph,embryonic/larval central nervous system,embryonic/larval brain,gonad,testis,wing disc,haltere disc,ventral thoracic disc,eye-antennal disc,genital disc,ring gland" FBgn0015557 tor::tub tor::tub http://flybase.org/reports/FBgn0015557 - engineered_fusion_gene - - - tor::tub - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261550 CG42668 - http://flybase.org/reports/FBgn0261550 protein_coding_gene - - - "CG42668, CG5077, CG15684" "IPR000648:Oxysterol-binding protein, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR018494:Oxysterol-binding protein, conserved site" CG42668 11-Aug-17 DroID_v2017_08 "Drer\osbpl10, Drer\osbpl8, Drer\osbpl11, Drer\osbpl9, Drer\LOC100334085, Drer\osbpl5" "Scer\OSH6, Scer\OSH7, Scer\HES1, Scer\OSH3, Scer\KES1" "Cele\obr-4, Cele\obr-3" "Xtro\osbpl10, Xtro\osbpl8, Xtro\osbpl11, Xtro\osbpl9" "Mmus\Osbpl8, Mmus\Osbpl10, Mmus\Osbpl11, Mmus\Osbpl5, Mmus\Osbpl9" "Hsap\OSBPL5, Hsap\OSBPL8, Hsap\OSBPL11, Hsap\OSBPL10, Hsap\OSBPL9" FBgn0037548 CG7900 - http://flybase.org/reports/FBgn0037548 protein_coding_gene - - - CG7900 IPR023631:Amidase signature domain CG7900 11-Aug-17 DroID_v2017_08 "Drer\faah2a, Drer\faah2b, Drer\faah" "Scer\HER2, Scer\AMD2" "Cele\faah-4, Cele\faah-5, Cele\faah-6, Cele\Y53F4B.18, Cele\Y41D4A.6, Cele\faah-3, Cele\faah-1, Cele\faah-2" "Xtro\faah.1, Xtro\faah.2, Xtro\faah.3, Xtro\faah2" "Mmus\Qrsl1, Mmus\Faah" "Hsap\FAAH, Hsap\FAAH2, Hsap\QRSL1" viable FBgn0003140 PpY-55A Protein phosphatase Y at 55A http://flybase.org/reports/FBgn0003140 "FBgn0005781, FBgn0034285" protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity protein dephosphorylation ; GO:0006470 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "DmPpY-55A, PPY 55A, CG10930, PPY, D19, PpD19, PpY-55A" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG10930 11-Aug-17 DroID_v2017_08 "Drer\ppp1cb, Drer\ppp1caa, Drer\ppp1cc, Drer\ppp1cbl" "Scer\GLC7, Scer\PPQ1, Scer\PPG1, Scer\PPZ1, Scer\PPZ2" "Cele\F52H3.6, Cele\gsp-2, Cele\T25B9.2, Cele\Y69E1A.4, Cele\pef-1, Cele\gsp-1, Cele\F58G1.3, Cele\pph-1, Cele\R13A5.11, Cele\ZK354.9, Cele\ZK938.1, Cele\F25B3.4, Cele\C06A1.3, Cele\F23B12.1, Cele\C34D4.2, Cele\C30A5.4, Cele\F22D6.9, Cele\Y71G12B.30" "Xtro\ppp1cb, Xtro\ppp1ca, Xtro\ppp1cc" "Mmus\Ppp1cb, Mmus\Ppef1, Mmus\Ppp1ca, Mmus\Ppp1cc" "Hsap\PPP1CC, Hsap\PPP1CB, Hsap\PPEF1, Hsap\PPP1CA" " spermatogenesis && adult stage , pupal stage " testis

" spermatogenesis && adult stage , larval stage , larval stage && S " " testis

, cyst cell

" viable FBgn0065464 l(2)SH1353 lethal (2) SH1353 http://flybase.org/reports/FBgn0065464 gene - - - "l(2)SH1353, l(2)SH2 1353" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033463 CG1513 - http://flybase.org/reports/FBgn0033463 protein_coding_gene - - - CG1513 "IPR000648:Oxysterol-binding protein, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR018494:Oxysterol-binding protein, conserved site" CG1513 11-Aug-17 DroID_v2017_08 "Drer\osbpl8, Drer\LOC100334085, Drer\osbpl11, Drer\osbpl10, Drer\osbpl5, Drer\osbpl9" "Scer\OSH7, Scer\OSH6, Scer\KES1, Scer\HES1" "Cele\obr-4, Cele\obr-3" "Xtro\osbpl9, Xtro\osbpl10, Xtro\osbpl11, Xtro\osbpl8" "Mmus\Osbpl10, Mmus\Plekha8, Mmus\Osbpl5, Mmus\Osbpl11, Mmus\Osbpl8, Mmus\Osbpl9" "Hsap\OSBPL10, Hsap\OSBPL11, Hsap\PLEKHA8, Hsap\OSBPL8, Hsap\OSBPL5, Hsap\OSBPL9" viable DRSC06553 I -0.420651018 -1.687705469 -0.093259941 -0.014661411 1.103005431 1.340763635 FBgn0002717 mel melanized http://flybase.org/reports/FBgn0002717 - gene - - - mel - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,good,fertile,eye color defective,recessive,visible,body color defective" "pigment cell,wing,distal,trident" FBgn0259924 1A-RE 1A regulatory element http://flybase.org/reports/FBgn0259924 insulator - - - 1A-RE - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085434 NaCP60E Na channel protein 60E http://flybase.org/reports/FBgn0085434 protein_coding_gene voltage-gated sodium channel activity ; GO:0005248 | inferred from sequence or structural similarity with UniProtKB:P04774 voltage-gated cation channel activity ; GO:0022843 | inferred from direct assay voltage-gated sodium channel activity ; GO:0005248 | non-traceable author statement voltage-gated sodium channel activity ; GO:0005248 | inferred from biological aspect of ancestor with PANTHER:PTN000798901 membrane depolarization during action potential ; GO:0086010 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 sodium ion transport ; GO:0006814 | non-traceable author statement neuronal action potential ; GO:0019228 | inferred from biological aspect of ancestor with PANTHER:PTN000798901 olfactory behavior ; GO:0042048 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern sodium ion transmembrane transport ; GO:0035725 | inferred from sequence or structural similarity with UniProtKB:P04774 voltage-gated sodium channel complex ; GO:0001518 | inferred from electronic annotation with InterPro:IPR001696 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:P04774 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 plasma membrane ; GO:0005886 | non-traceable author statement "CG34405, smi60E, DSCI, CG9071, dsc1, CT24831, DSC, DSC1, DIC60, Na-CP, NaCP60E, CG18506, dsc" "IPR001696:Voltage gated sodium channel, alpha subunit, IPR005821:Ion transport domain, IPR000048:IQ motif, EF-hand binding site, IPR028820:Sodium channel protein 60E, IPR031649:Voltage-dependent L-type calcium channel, IQ-associated domain" CG34405 11-Aug-17 DroID_v2017_08 "Drer\scn1lab, Drer\cacna1aa, Drer\nalcn, Drer\cacna1e, Drer\scn4ab, Drer\cacna1ba, Drer\cacna1fb, Drer\scn12aa, Drer\scn1a, Drer\cacna1sb, Drer\cacna1ab, Drer\scn8ab, Drer\cacna1c, Drer\cacna1eb, Drer\cacna1da, Drer\scn8aa, Drer\cacna1bb, Drer\cacna1fa, Drer\scn4aa, Drer\cacna1sa" Scer\CCH1 "Cele\egl-19, Cele\unc-2, Cele\nca-2, Cele\unc-77" "Xtro\scn5a, Xtro\cacna1f, Xtro\scn4a, Xtro\cacna1a, Xtro\nalcn, Xtro\cacna1s, Xtro\scn3a" "Mmus\Catsper2, Mmus\Scn2a, Mmus\Cacna1b, Mmus\Scn11a, Mmus\Catsper3, Mmus\Cacna1f, Mmus\Scn3a, Mmus\Scn4a, Mmus\Cacna1e, Mmus\Scn5a, Mmus\Cacna1d, Mmus\Scn7a, Mmus\Cacna1s, Mmus\Scn9a, Mmus\Scn1a, Mmus\Cacna1a, Mmus\Scn8a, Mmus\Nalcn, Mmus\Scn10a, Mmus\Cacna1c" "Hsap\SCN5A, Hsap\SCN3A, Hsap\SCN1A, Hsap\SCN4A, Hsap\CACNA1D, Hsap\SCN9A, Hsap\SCN2A, Hsap\SCN8A, Hsap\NALCN, Hsap\SCN11A, Hsap\CACNA1F, Hsap\SCN7A, Hsap\CACNA1A, Hsap\SCN10A, Hsap\CACNA1S, Hsap\CACNA1B, Hsap\CATSPER3, Hsap\CACNA1C" FBgn0034725 CG6044 - http://flybase.org/reports/FBgn0034725 protein_coding_gene - - - "BcDNA:RH44966, CG6044" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG6044 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC04522 K -0.46880436 -0.29337005 -0.951804673 0.246273725 1.659626672 -0.320616216 FBgn0032375 CG14932 - http://flybase.org/reports/FBgn0032375 protein_coding_gene - - - CG14932 - CG14932 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,supernumerary" FBgn0026649 l(2)61E5 lethal (2) 61E5 http://flybase.org/reports/FBgn0026649 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)61E5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone,oocyte nucleus,nurse cell" FBgn0038447 CG14892 - http://flybase.org/reports/FBgn0038447 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP175, CG14892" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG14892 11-Aug-17 DroID_v2017_08 "Drer\zgc:165423, Drer\ovch1, Drer\si:dkeyp-93a5.3, Drer\si:dkey-16l2.17, Drer\si:ch211-165b19.9, Drer\LOC100004427, Drer\gzmk, Drer\zgc:163079, Drer\gzma, Drer\zgc:92313, Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.8, Drer\gzm3, Drer\cfd" - "Cele\try-1, Cele\svh-1, Cele\try-6" Xtro\klkb1 "Mmus\Klk9, Mmus\Klk15, Mmus\F11, Mmus\Prss48, Mmus\Klkb1" "Hsap\TMPRSS12, Hsap\KLK9, Hsap\KLKB1, Hsap\KLK15, Hsap\F11" FBgn0029182 E(Khc)ek5 E(Khc)ek5 http://flybase.org/reports/FBgn0029182 gene - - - E(Khc)ek5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262382 mir-1010 mir-1010 stem loop http://flybase.org/reports/FBgn0262382 miRNA_gene - - - "mir-1010, miR-1010, dme-mir-1010, CR42905, dme-miR-1010" - CR42905 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038301 CG6654 - http://flybase.org/reports/FBgn0038301 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR016177 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG6654 "IPR012934:Zinc finger, AD-type, IPR016177:DNA-binding domain, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6654 11-Aug-17 DroID_v2017_08 "Drer\gtf3aa, Drer\zbtb34, Drer\zgc:76872, Drer\zbtb37, Drer\zbtb12.1, Drer\LOC103910825, Drer\hic1l, Drer\zgc:163077, Drer\si:ch211-236k19.4, Drer\zbtb22b, Drer\insm1b, Drer\zbtb12.2, Drer\zbtb20, Drer\LOC100333583, Drer\si:ch211-142b24.6, Drer\zbtb21, Drer\zbtb8a, Drer\LOC568955, Drer\zbtb14, Drer\insm1a, Drer\zbtb43, Drer\zbtb22a, Drer\zgc:171551, Drer\zbtb48, Drer\bcl6a, Drer\si:dkey-262g12.3, Drer\hic2" Scer\PZF1 "Cele\F10B5.3, Cele\klf-3, Cele\hinf-1, Cele\pqm-1, Cele\ztf-23, Cele\Y55F3AM.14, Cele\fezf-1, Cele\Y111B2A.10, Cele\F21A9.2, Cele\M03D4.4" "Xtro\zbtb14, Xtro\gzf1, Xtro\znf238.2, Xtro\zbtb9, Xtro\insm2, Xtro\zbtb34, Xtro\e4f1, Xtro\zbtb26, Xtro\zbtb37, Xtro\hic1, Xtro\zbtb43, Xtro\zbtb7c, Xtro\hic2" "Mmus\Zfp865, Mmus\Insm1, Mmus\Zbtb39, Mmus\Zfp651, Mmus\Zbtb45, Mmus\Zfp872, Mmus\Zfp114, Mmus\Zbtb6, Mmus\Zfp746, Mmus\Zbtb22, Mmus\Mzf1, Mmus\Zbtb38, Mmus\Zbtb43, Mmus\Zbtb12, Mmus\Gzf1, Mmus\Zfp282, Mmus\Zbtb14, Mmus\Zbtb9, Mmus\Zbtb33, Mmus\Insm2, Mmus\Zfp354c, Mmus\Zfp777, Mmus\Zfp790, Mmus\Zbtb2, Mmus\Zbtb26, Mmus\Gtf3a, Mmus\Mynn, Mmus\Zfp661, Mmus\Zbtb42, Mmus\Zkscan4, Mmus\Zbtb18, Mmus\Hic2, Mmus\Zbtb32, Mmus\Zfp791, Mmus\Zbtb34, Mmus\Zbtb37" "Hsap\ZNF846, Hsap\ZNF445, Hsap\ZBTB42, Hsap\HIC2, Hsap\ZNF471, Hsap\ZNF665, Hsap\ZNF236, Hsap\ZNF212, Hsap\ZNF7, Hsap\ZBTB45, Hsap\ZBTB18, Hsap\ZBTB34, Hsap\ZBTB26, Hsap\ZFAT, Hsap\ZBTB38, Hsap\ZNF783, Hsap\ZBTB37, Hsap\ZNF844, Hsap\ZNF584, Hsap\ZNF493, Hsap\ZBTB5, Hsap\ZNF829, Hsap\ZBTB32, Hsap\ZNF571, Hsap\ZBTB41, Hsap\MYNN, Hsap\ZBTB33, Hsap\INSM2, Hsap\ZNF354B, Hsap\ZNF398, Hsap\ZNF668, Hsap\GZF1, Hsap\ZNF746, Hsap\ZBTB3, Hsap\ZBTB22, Hsap\ZBTB43, Hsap\ZBTB24, Hsap\ZNF517, Hsap\ZBTB12, Hsap\ZNF621, Hsap\ZBTB14, Hsap\ZNF696, Hsap\ZNF263, Hsap\ZSCAN32, Hsap\ZNF777, Hsap\ZBTB39, Hsap\INSM1, Hsap\ZNF679, Hsap\ZNF131, Hsap\ZNF223, Hsap\ZBTB48, Hsap\ZNF134, Hsap\GTF3A, Hsap\ZBTB6, Hsap\ZNF282, Hsap\ZNF785" FBgn0263965 BG02049 - http://flybase.org/reports/FBgn0263965 gene - - - BG02049 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,female limited,starvation stress response defective,male limited,temperature response defective,gravitaxis defective" FBgn0060494 l(3)S108406 lethal (3) S108406 http://flybase.org/reports/FBgn0060494 gene - - - "1084/06, l(3)S108406" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0016028 l(3)89Ek lethal (3) 89Ek http://flybase.org/reports/FBgn0016028 - gene - - - l(3)89Ek - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043036 l(2)42Bh lethal (2) 42Bh http://flybase.org/reports/FBgn0043036 gene - - - l(2)42Bh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060919 l(3)S042532 lethal (3) S042532 http://flybase.org/reports/FBgn0060919 gene - - - "0425/32, l(3)S042532" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0024806 DIP2 DISCO Interacting Protein 2 http://flybase.org/reports/FBgn0024806 FBgn0035119 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 protein binding ; GO:0005515 | inferred from physical interaction with disco metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - "CG7020, Ddip2, DIP2" "IPR000873:AMP-dependent synthetase/ligase, IPR010506:DMAP1-binding domain" CG7020 11-Aug-17 DroID_v2017_08 "Drer\LOC101885764, Drer\dip2ba, Drer\dip2a, Drer\dip2ca, Drer\dip2cb, Drer\dip2bb" Scer\CMR2 Cele\dip-2 "Xtro\dip2c, Xtro\dip2b, Xtro\dip2a" "Mmus\Dip2c, Mmus\Dip2b, Mmus\Dip2a" "Hsap\DIP2A, Hsap\DIP2C, Hsap\DIP2B" "viable,fertile" FBgn0259438 EP-167 - http://flybase.org/reports/FBgn0259438 gene - - - EP-167 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing hair,wing" FBgn0019678 mor(1)13 mortality gene (1)13 http://flybase.org/reports/FBgn0019678 - gene - - - mor(1)13 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0033164 CG11112 - http://flybase.org/reports/FBgn0033164 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | non-traceable author statement extracellular space ; GO:0005615 | inferred from sequence model "CG11112, CT8227" - CG11112 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC05049 K 0.960574932 0.103053173 1.257624988 -1.302258417 -1.307054443 -1.572465754 FBgn0020928 Hsf::Hsap\HSF1 HSF1 http://flybase.org/reports/FBgn0020928 - engineered_fusion_gene - - - Hsf::Hsap\HSF1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051414 Gba1b Glucocerebrosidase 1b http://flybase.org/reports/FBgn0051414 protein_coding_gene glucosylceramidase activity ; GO:0004348 | inferred from genetic interaction with Gba1a neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with Gba1a memory ; GO:0007613 | inferred from genetic interaction with Gba1a adult locomotory behavior ; GO:0008344 | inferred from genetic interaction with Gba1a glucosylceramide catabolic process ; GO:0006680 | inferred from biological aspect of ancestor with PANTHER:PTN001667738 determination of adult lifespan ; GO:0008340 | inferred from genetic interaction with Gba1a cellular response to unfolded protein ; GO:0034620 | inferred from genetic interaction with Gba1a lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000869635 "CG10299, dGBA1b, CG31414, Gba1b" "IPR001139:Glycoside hydrolase family 30, IPR017853:Glycoside hydrolase superfamily, IPR033452:Glycosyl hydrolase family 30, beta sandwich domain, IPR033453:Glycosyl hydrolase family 30, TIM-barrel domain" CG31414 11-Aug-17 DroID_v2017_08 Drer\gba - "Cele\gba-3, Cele\gba-2, Cele\gba-1, Cele\gba-4" - Mmus\Gba Hsap\GBA viable FBgn0010165 psb pseudobeadex http://flybase.org/reports/FBgn0010165 - gene - - - psb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260064 2L3500 - http://flybase.org/reports/FBgn0260064 gene - - - 2L3500 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0265833 CG44622 - http://flybase.org/reports/FBgn0265833 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lincRNA.354, CG44622" - CG44622 11-Aug-17 DroID_v2017_08 - - "Cele\srh-72, Cele\sri-25, Cele\hrg-5, Cele\srbc-83, Cele\srh-190" - "Mmus\Gpr141, Mmus\A530099J19Rik" - FBgn0032790 CG10194 - http://flybase.org/reports/FBgn0032790 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797" phagocytosis ; GO:0006909 | inferred from mutant phenotype - CG10194 "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like" CG10194 11-Aug-17 DroID_v2017_08 Drer\nudt19 - Cele\ndx-7 Xtro\nudt19 Mmus\Nudt19 Hsap\NUDT19 viable FBgn0026785 P29 P29 http://flybase.org/reports/FBgn0026785 - gene - - - P29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,viable" postorbital bristle FBgn0051357 CG31357 - http://flybase.org/reports/FBgn0051357 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000255799 negative regulation of gluconeogenesis ; GO:0045721 | inferred from electronic annotation with InterPro:IPR027714 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 negative regulation of apoptotic process ; GO:0043066 | inferred from biological aspect of ancestor with PANTHER:PTN000255802 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 GID complex ; GO:0034657 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 "CG13638, CG31357" "IPR024964:CTLH/CRA C-terminal to LisH motif domain, IPR006594:LIS1 homology motif, IPR006595:CTLH, C-terminal LisH motif, IPR013144:CRA domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027714:Protein Fyv10/Macrophage erythroblast attacher" CG31357 11-Aug-17 DroID_v2017_08 Drer\maea Scer\FYV10 Cele\maea-1 Xtro\maea Mmus\Maea Hsap\MAEA "viable,fertile" FBgn0044424 M80-A32 M80-A32 http://flybase.org/reports/FBgn0044424 gene molecular_function ; GO:0003674 | no biological data available establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype eye photoreceptor cell differentiation ; GO:0001754 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "M80#A32, M80-A32" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "eye photoreceptor cell,somatic clone,photoreceptor cell R4,cell autonomous" FBgn0085248 CG34219 - http://flybase.org/reports/FBgn0085248 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34219 - CG34219 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002164 l(2)Sp8 lethal (2) Sp8 http://flybase.org/reports/FBgn0002164 - gene - - - l(2)Sp8 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0250815 Jon65Aiv Jonah 65Aiv http://flybase.org/reports/FBgn0250815 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG6467, SP117, Jon65A, Jon65Aiv, BEST:GH23808, jon65aiv, Jon65" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG6467 11-Aug-17 DroID_v2017_08 "Drer\zgc:112368, Drer\zgc:92041, Drer\zgc:92745, Drer\ela3l, Drer\zgc:112302, Drer\zgc:112285" - - - "Mmus\Ctrc, Mmus\Ctrl, Mmus\Cela3b, Mmus\Cela3a, Mmus\Cela2a, Mmus\Cela1, Mmus\Ctrb1" Hsap\CELA2A FBgn0069919 CG41133 - http://flybase.org/reports/FBgn0069919 protein_coding_gene - - - CG41133 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028257 l(3)72Dq lethal (3) 72Dq http://flybase.org/reports/FBgn0028257 gene - - - l(3)72Dq - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033265 coil coilin http://flybase.org/reports/FBgn0033265 protein_coding_gene - Cajal body organization ; GO:0030576 | inferred from mutant phenotype histone locus body ; GO:0035363 | inferred from direct assay Cajal body ; GO:0015030 | inferred from direct assay nuclear body ; GO:0016604 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CG8710, Coilin, coil, coilin" "IPR031722:Coilin, N-terminal domain" CG8710 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" Cajal body FBgn0003295 ru roughoid http://flybase.org/reports/FBgn0003295 "FBgn0035215, FBgn0041724" protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 "compound eye cone cell fate commitment ; GO:0042676 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype heart process ; GO:0003015 | inferred from mutant phenotype positive regulation of protein secretion ; GO:0050714 | inferred from genetic interaction with spi protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 compound eye photoreceptor fate commitment ; GO:0001752 | inferred from genetic interaction with rho epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement" apical part of cell ; GO:0045177 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001117493 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with rho endoplasmic reticulum ; GO:0005783 | inferred from direct assay "rho3, rho-3, Rho-3, Rho-related [62A1], CG1214, ru, Rho3" "IPR002610:Peptidase S54, rhomboid, IPR017213:Peptidase S54, rhomboid, metazoan, IPR022764:Peptidase S54, rhomboid domain" CG1214 11-Aug-17 DroID_v2017_08 "Drer\rhbdl3, Drer\rhbdl1, Drer\rhbdl2" - "Cele\rom-2, Cele\rom-1" Xtro\rhbdl2 "Mmus\Rhbdl3, Mmus\Rhbdl2, Mmus\Rhbdl1" "Hsap\RHBDL2, Hsap\RHBDL1, Hsap\RHBDL3" "wild-type,cell polarity defective,planar polarity defective,recessive,visible,neuroanatomy defective,neurophysiology defective,viable" "embryonic/larval ganglionic branch,eye,ommatidium,photoreceptor,cone cell,pigment cell,adult heart chamber,ganglionic branch 1,eye photoreceptor cell,optic cartridge,wing,wing vein,ectopic,egg" FBgn0086024 snoRNA:Me28S-A2589b - http://flybase.org/reports/FBgn0086024 snoRNA_gene - - - "snoRNA:Me28S-A2589b, Me28S-Am2589b, CR34653" - CR34653 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262223 mir-994 mir-994 stem loop http://flybase.org/reports/FBgn0262223 miRNA_gene - - - "miR-994, mir-994, dme-mir-994, CR42930" - CR42930 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0019751 l(1)815-23 lethal (1) 815-23 http://flybase.org/reports/FBgn0019751 - gene - - - l(1)815-23 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031168 CG1722 - http://flybase.org/reports/FBgn0031168 protein_coding_gene - - - CG1722 - CG1722 11-Aug-17 DroID_v2017_08 - - "Cele\H27M09.5, Cele\Y119C1B.1, Cele\Y39G10AR.16" - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0264882 CR44073 - http://flybase.org/reports/FBgn0264882 non_protein_coding_gene - - - CR44073 - CR44073 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039868 CG11563 - http://flybase.org/reports/FBgn0039868 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:26934 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000997248 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:26934 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000997248 "BcDNA:RE07994, CG11563" IPR019002:Ribosome biogenesis protein Nop16 CG11563 11-Aug-17 DroID_v2017_08 Drer\nop16 Scer\NOP16 Cele\ZK265.6 Xtro\nop16 Mmus\Nop16 Hsap\NOP16 "viable,fertile" FBgn0264309 CG43784 - http://flybase.org/reports/FBgn0264309 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43784, CG43784" - CG43784 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002211 l(3)67BDi lethal (3) 67BDi http://flybase.org/reports/FBgn0002211 - gene - - - l(3)67BDi - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016898 l(3)64Ch lethal (3) 64Ch http://flybase.org/reports/FBgn0016898 - gene - - - l(3)64Ch - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044498 DTD44.5 DTD44.5 http://flybase.org/reports/FBgn0044498 gene - - - DTD44.5 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0250739 l(3)S026915 lethal (3) S026915 http://flybase.org/reports/FBgn0250739 gene - - - "l(3)S026915, l(3)s026915" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266816 CR45278 - http://flybase.org/reports/FBgn0266816 non_protein_coding_gene - - - CR45278 - CR45278 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031098 CG17068 - http://flybase.org/reports/FBgn0031098 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 neurogenesis ; GO:0022008 | inferred from biological aspect of ancestor with PANTHER:PTN001229949 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001229949 CG17068 "IPR000210:BTB/POZ domain, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain" CG17068 11-Aug-17 DroID_v2017_08 "Drer\btbd3b, Drer\btbd6b, Drer\klhl41b, Drer\btbd17b, Drer\btbd2, Drer\btbd6a, Drer\btbd3a" Scer\YIL001W - "Xtro\btbd6, Xtro\btbd1, Xtro\klhl41, Xtro\btbd2, Xtro\btbd3" "Mmus\Btbd3, Mmus\Btbd2, Mmus\Btbd17, Mmus\Btbd1, Mmus\Btbd6" "Hsap\BTBD2, Hsap\BTBD3, Hsap\BTBD1, Hsap\BTBD6, Hsap\BTBD17" "viable,body color defective" mesothoracic tergum FBgn0267116 CR45556 - http://flybase.org/reports/FBgn0267116 non_protein_coding_gene - - - CR45556 - CR45556 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001559 l(1)19Da lethal (1) 19Da http://flybase.org/reports/FBgn0001559 - gene - - - l(1)19Da - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005086 fs(2)OW810 female sterile (2) OW810 http://flybase.org/reports/FBgn0005086 - gene - - - fs(2)OW810 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052590 CG32590 - http://flybase.org/reports/FBgn0052590 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32590 IPR019320:BLOC-1-related complex subunit 8 CG32590 11-Aug-17 DroID_v2017_08 Drer\borcs8 - Cele\blos-9 Xtro\borcs8 Mmus\Borcs8 Hsap\BORCS8 FBgn0062563 P12 P12 http://flybase.org/reports/FBgn0062563 gene - - - P12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001113 glide glide http://flybase.org/reports/FBgn0001113 - gene - - - "gli, glide" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male,reduced,male sterile,recessive" "wing,tergite" FBgn0005653 Mst59Dc Male-specific transcript 59Dc http://flybase.org/reports/FBgn0005653 - gene - - - Mst59Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025489 l(3)82EFb lethal (3) 82EFb http://flybase.org/reports/FBgn0025489 - gene - - - l(3)82EFb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015973 l(2)PC4-427 lethal (2) PC4-427 http://flybase.org/reports/FBgn0015973 - gene - - - "l(2)PC4-M, l(2)PC4-427" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028044 l(3)S097907a lethal (3) S097907a http://flybase.org/reports/FBgn0028044 gene - - - "979/7, 762/1, 1429/10, 1412/03, 1285/01, 1227/09, 1125/17, 0979/07, 0741/07, 0677/12, 0183/01, l(3)S097907, l(3)S097907a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of prepupal stage,some die during prepupal stage" FBgn0033115 Spn42De Serpin 42De http://flybase.org/reports/FBgn0033115 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 extracellular space ; GO:0005615 | inferred from sequence model "Spn42De, CG9460" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG9460 11-Aug-17 DroID_v2017_08 "Drer\serping1, Drer\serpinb1, Drer\serpinf2b, Drer\si:ch211-186e20.7, Drer\serpinc1, Drer\zgc:173729, Drer\zgc:174260, Drer\serpinf2a, Drer\serpinb1l2, Drer\serpini1, Drer\serpine2, Drer\serpina10a, Drer\serpinf1, Drer\serpine1, Drer\serpind1, Drer\serpinb1l3, Drer\serpina1l, Drer\zgc:113828, Drer\si:ch1073-416d2.3, Drer\agt, Drer\serpine3, Drer\zgc:174259, Drer\serpina7" - "Cele\C28G1.2, Cele\srp-2, Cele\srp-3, Cele\srp-6, Cele\srp-7, Cele\srp-1, Cele\srp-8" "Xtro\serpina3, Xtro\serpine1, Xtro\serpinb5, Xtro\serpinf1, Xtro\serpinb4, Xtro\serpina3k, Xtro\serpina10, Xtro\serpinb6, Xtro\serpini1, Xtro\serpind1, Xtro\serpina3m, Xtro\serpinc1, Xtro\serpine2, Xtro\serpinb1, Xtro\serpina1, Xtro\serpinb11, Xtro\serpini2" "Mmus\Serpina10, Mmus\Serpina3i, Mmus\Serpinb9, Mmus\Serpinb5, Mmus\Serpina3j, Mmus\Serpinb9c, Mmus\Serpinb1b, Mmus\Serpina11, Mmus\Serpinb9b, Mmus\Serpine3, Mmus\Serpinb3d, Mmus\Serpinb3c, Mmus\Serpine1, Mmus\Serpinb6b, Mmus\Serpina9, Mmus\Serpina1f, Mmus\Serpinb6e, Mmus\Serpinb3b, Mmus\Serpinf1, Mmus\Serpinb3a, Mmus\Serpina12, Mmus\Serpina16, Mmus\Serpina1e, Mmus\Serpina3g, Mmus\Serpinb7, Mmus\Serpinb11, Mmus\Serpinb6a, Mmus\Serpine2, Mmus\Serpinb12, Mmus\Serpina3k, Mmus\Serpinb1a, Mmus\Serpind1, Mmus\Serpina3b, Mmus\Serpina3a, Mmus\Serpina3n, Mmus\Serpinb6c, Mmus\Serpina1d, Mmus\Serpinb2, Mmus\Serpina3f, Mmus\Serpina6, Mmus\Serpini1, Mmus\Serpinb9e, Mmus\Serpinb8, Mmus\Serpinb6d, Mmus\Serpina3c, Mmus\Serpina1c, Mmus\Serpinb1c, Mmus\Serpina1a, Mmus\Serpinf2, Mmus\Agt, Mmus\Serpinb9f, Mmus\Serpini2, Mmus\Serpinb10, Mmus\Serpinc1, Mmus\Serpina7, Mmus\Serpinb13, Mmus\Serpina5" "Hsap\SERPINB11, Hsap\SERPINB4, Hsap\SERPINB12, Hsap\AGT, Hsap\SERPINA5, Hsap\SERPINA10, Hsap\SERPINB2, Hsap\SERPINB6, Hsap\SERPINB7, Hsap\SERPINA1, Hsap\SERPINB5, Hsap\SERPINA7, Hsap\SERPINB3, Hsap\SERPINA11, Hsap\SERPIND1, Hsap\SERPINI1, Hsap\SERPINA6, Hsap\SERPINA9, Hsap\SERPINB8, Hsap\SERPINC1, Hsap\SERPINB1, Hsap\SERPINF1, Hsap\SERPINB10, Hsap\SERPINI2, Hsap\SERPINA4, Hsap\SERPINE1, Hsap\SERPINB13, Hsap\SERPINA12, Hsap\SERPINA2, Hsap\SERPINA3, Hsap\SERPINF2, Hsap\SERPINE3, Hsap\SERPINB9, Hsap\SERPINE2" viable FBgn0014114 anon-84Bc anon-84Bc http://flybase.org/reports/FBgn0014114 - gene - - - "Y2, anon-84Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && oogenesis stage , embryonic stage && larval stage && pupal stage " unfertilized egg

FBgn0034897 Sesn Sestrin http://flybase.org/reports/FBgn0034897 protein_coding_gene - regulation of response to reactive oxygen species ; GO:1901031 | inferred from electronic annotation with InterPro:IPR006730 negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from mutant phenotype multicellular organism aging ; GO:0010259 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype regulation of reactive oxygen species metabolic process ; GO:2000377 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006730 "BEST:GH20113, BcDNA:GH20113, Sesn, dSesn, CG11299" "IPR006730:Sestrin, IPR029032:AhpD-like" CG11299 11-Aug-17 DroID_v2017_08 "Drer\sesn1, Drer\eif4e1c, Drer\eif4e1b, Drer\sesn2, Drer\sesn3, Drer\si:zfos-80g12.1, Drer\eif4ea" - "Cele\sesn-1, Cele\ife-1, Cele\ife-2" "Xtro\sesn1, Xtro\eif4e1b, Xtro\eif4e, Xtro\sesn2, Xtro\sesn3" "Mmus\Eif4e1b, Mmus\Sesn2, Mmus\Eif4e, Mmus\Sesn3, Mmus\Sesn1" "Hsap\EIF4E1B, Hsap\EIF4E, Hsap\SESN1, Hsap\SESN3, Hsap\SESN2" "aging defective,visible,cell growth defective,viable,behavior defective,recessive" "myofibril,sarcomere,M band,Z disc,actomyosin,mitochondrion,wing blade" FBgn0267372 T:KASH-Msp300 KASH domain of Msp300 http://flybase.org/reports/FBgn0267372 engineered_tag - - - T:KASH-Msp300 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045848 l(4)102Fe lethal (4) 102Fe http://flybase.org/reports/FBgn0045848 gene - - - l(4)102Fe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265427 CR44339 - http://flybase.org/reports/FBgn0265427 non_protein_coding_gene - - - "CR44339, lincRNA.296" - CR44339 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025009 E(tkv)D1 E(tkv)D1 http://flybase.org/reports/FBgn0025009 - gene - - - "D1, E(tkv)D1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031149 Stt3A Catalytic subunit 3A of the oligosaccharyltransferase complex http://flybase.org/reports/FBgn0031149 protein_coding_gene dolichyl-diphosphooligosaccharide-protein glycotransferase activity ; GO:0004579 | inferred from biological aspect of ancestor with PANTHER:PTN000356206 post-translational protein modification ; GO:0043687 | inferred from biological aspect of ancestor with PANTHER:PTN000356206 chaeta development ; GO:0022416 | inferred from genetic interaction with Chi wing disc development ; GO:0035220 | inferred from genetic interaction with Bx protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from biological aspect of ancestor with PANTHER:PTN000356206 oligosaccharyltransferase complex ; GO:0008250 | inferred from biological aspect of ancestor with PANTHER:PTN000356206 endomembrane system ; GO:0012505 | inferred from direct assay "Stt3A, CG1518, STT" "IPR003674:Oligosaccharyl transferase, STT3 subunit" CG1518 11-Aug-17 DroID_v2017_08 "Drer\stt3b, Drer\stt3a" Scer\STT3 Cele\stt-3 Xtro\stt3a "Mmus\Stt3a, Mmus\Stt3b" "Hsap\STT3A, Hsap\STT3B" "viable,visible" mesothoracic tergum FBgn0033240 CG2906 - http://flybase.org/reports/FBgn0033240 protein_coding_gene - - - CG2906 IPR025714:Methyltransferase domain CG2906 11-Aug-17 DroID_v2017_08 "Drer\mettl25, Drer\rrnad1" - Cele\F25H2.12 "Xtro\rrnad1, Xtro\mettl25" "Mmus\Mettl25, Mmus\Rrnad1" "Hsap\RRNAD1, Hsap\METTL25" viable DRSC06841 K -0.406639442 0.834796788 -0.53155024 0.643191129 -1.181227739 -1.605465623 FBgn0001899 l(2)21Fe lethal (2) 21Fe http://flybase.org/reports/FBgn0001899 - gene - - - "l(2)neh-13, l(2)neh13, l(2)21Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005094 fs(2)OWc6 female sterile (2) OWc6 http://flybase.org/reports/FBgn0005094 - gene - - - fs(2)OWc6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001880 l(1)YE17 lethal (1) YE17 http://flybase.org/reports/FBgn0001880 - gene - - - l(1)YE17 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085646 CG41427 - http://flybase.org/reports/FBgn0085646 protein_coding_gene - - - CG41427 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0047092 CR32730 - http://flybase.org/reports/FBgn0047092 non_protein_coding_gene - - - "BcDNA:RE54930, CR32730, MRE32" - CR32730 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22957 I 1.998860757 0.55375019 0.130235958 1.236300078 -0.313156906 0.463148486 FBgn0010453 Wnt4 Wnt oncogene analog 4 http://flybase.org/reports/FBgn0010453 - protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with fj receptor binding ; GO:0005102 | inferred from sequence or structural similarity with wg signal transducer activity ; GO:0004871 | non-traceable author statement frizzled binding ; GO:0005109 | inferred from physical interaction with fz, fz2, fz4" "non-canonical Wnt signaling pathway ; GO:0035567 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype Wnt signaling pathway, planar cell polarity pathway ; GO:0060071 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype female gonad development ; GO:0008585 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with wg retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype neural retina development ; GO:0003407 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from genetic interaction with fj" extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 extracellular region ; GO:0005576 | non-traceable author statement extracellular region ; GO:0005576 | inferred from sequence or structural similarity with wg cell surface ; GO:0009986 | inferred from direct assay "Wnt4, DWnt4, wnt4, Wnt-4, Dwnt4, DWnt-4, Wnt, wnt-4, clone 2.4, anon-EST:Liang-2.4, CG4698, Dm DWnt4, WNT4" "IPR018161:Wnt protein, conserved site, IPR005817:Wnt, IPR015943:WD40/YVTN repeat-like-containing domain" CG4698 11-Aug-17 DroID_v2017_08 "Drer\wnt2ba, Drer\wnt5b, Drer\wnt11, Drer\wnt5a, Drer\wnt8a, Drer\wnt4a, Drer\wnt7ba, Drer\wnt2, Drer\wnt2bb, Drer\wnt6a, Drer\wnt10a, Drer\wnt10b, Drer\wnt11r, Drer\wnt7bb, Drer\wnt9a, Drer\wnt1, Drer\wnt8b, Drer\wnt6b, Drer\LOC568110, Drer\wnt9b, Drer\wnt3a, Drer\wnt3, Drer\wnt4b, Drer\wnt7aa, Drer\wnt16" - "Cele\cwn-1, Cele\mom-2, Cele\lin-44, Cele\egl-20, Cele\cwn-2" "Xtro\wnt7a, Xtro\wnt4, Xtro\wnt11r, Xtro\wnt1, Xtro\wnt10b, Xtro\wnt3a, Xtro\wnt9b, Xtro\wnt8b, Xtro\wnt16, Xtro\wnt8a, Xtro\wnt7b, Xtro\wnt9b.2, Xtro\wnt11, Xtro\wnt2b, Xtro\wnt7c, Xtro\wnt5b" "Mmus\Wnt1, Mmus\Wnt7b, Mmus\Wnt10a, Mmus\Wnt3, Mmus\Wnt9a, Mmus\Wnt5b, Mmus\Wnt2, Mmus\Wnt9b, Mmus\Wnt5a, Mmus\Wnt8b, Mmus\Wnt10b, Mmus\Wnt3a, Mmus\Wnt8a, Mmus\Wnt4, Mmus\Wnt2b, Mmus\Wnt11, Mmus\Wnt7a, Mmus\Wnt6, Mmus\Wnt16" "Hsap\WNT6, Hsap\WNT10A, Hsap\WNT9B, Hsap\WNT8A, Hsap\WNT3, Hsap\WNT7A, Hsap\WNT7B, Hsap\WNT4, Hsap\WNT2, Hsap\WNT9A, Hsap\WNT5B, Hsap\WNT5A, Hsap\WNT1, Hsap\WNT8B, Hsap\WNT3A, Hsap\WNT10B, Hsap\WNT16, Hsap\WNT11, Hsap\WNT2B" " embryonic stage | stage 14 , embryonic stage , embryonic stage | stage 8-11 , embryonic stage | stage 16 " " embryonic/larval foregut

, parasegment 4 &&of visceral mesoderm

, ectoderm

,

segment polarity , embryonic/larval hindgut

, embryonic central nervous system

, gastric caecum

, parasegment 8 &&of visceral mesoderm

, midgut constriction 2

" " adult stage , pupal stage " " terminal filament basal cell

, epithelial sheath

, germarium region 2

, germarium region 1

" "neuroanatomy defective,sterile,recessive,partially lethal - majority die,some die during larval stage,visible,lethal,heat sensitive,planar polarity defective,somatic clone,lethal - all die before end of P-stage,some die during pharate adult stage,viable,partially" "lamina,neuron,eye photoreceptor cell,denticle row 1,denticle row 2,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,abdominal segment 9,abdominal segment 10,abdominal segment 11,abdominal segment,embryonic/larval optic stalk,presumptive embryonic salivary gland,ovary,germarium,egg chamber,ovarian sheath,ovariole,denticle,ectopic,embryonic/first instar larval cuticle,embryonic epidermis,dorsal,dorsal denticle,denticle belt,wing,heat sensitive,scutellum,mesothoracic tergum,wing margin bristle,wing sensillum,alula,haltere,wing disc,sternopleural bristle,supernumerary,dorsocentral bristle,posterior postalar bristle,scutellar bristle,anterior crossvein,wing hair,cell non-autonomous,somatic clone,embryonic ventral epidermis,eye equator,wing vein,eye,ventral compartment,ommatidium" DRSC00976 K -0.640386697 -1.39388873 0.564039281 -0.709771696 1.176869013 1.648467388 FBgn0027057 CSN1b COP9 signalosome subunit 1b http://flybase.org/reports/FBgn0027057 - protein_coding_gene NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs protein deneddylation ; GO:0000338 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay protein deneddylation ; GO:0000338 | inferred from sequence or structural similarity with HGNC:454 neurogenesis ; GO:0022008 | inferred from mutant phenotype COP9 signalosome ; GO:0008180 | inferred from biological aspect of ancestor with PANTHER:PTN000365417 COP9 signalosome ; GO:0008180 | inferred from mutant phenotype COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity with MGI:MGI:2384801 "CSN1, csn1, dCSN1, DCH1-2, Dch1-2, CH1-2, CG3889, CSN1b, Csn1B, Csn1b, CSN1B, Dch1" "IPR000717:Proteasome component (PCI) domain, IPR019585:26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1, IPR011990:Tetratricopeptide-like helical domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR033008:COP9 signalosome complex subunit 1" CG3889 11-Aug-17 DroID_v2017_08 Drer\gps1 Scer\RPN7 Cele\csn-1 Xtro\gps1 Mmus\Gps1 Hsap\GPS1 "viable,fertile,visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "wing,arista,sex comb,leg,embryonic/larval neuroblast,ganglion mother cell,chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0035405 CG15812 - http://flybase.org/reports/FBgn0035405 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 "CG15812, Pfk, pfk" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR007889:DNA binding HTH domain, Psq-type, IPR009057:Homeobox domain-like" CG15812 11-Aug-17 DroID_v2017_08 - - - - - Hsap\ZBTB9 "lethal,neuroanatomy defective,viable,visible,body color defective" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0014106 anon-4Ce anon-4Ce http://flybase.org/reports/FBgn0014106 - gene - - - "T15, anon-4Ce" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267010 CR45454 - http://flybase.org/reports/FBgn0267010 non_protein_coding_gene - - - CR45454 - CR45454 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002590 RpS5a Ribosomal protein S5a http://flybase.org/reports/FBgn0002590 - protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR020606 structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000235, InterPro:IPR005716, InterPro:IPR020606 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" small ribosomal subunit ; GO:0015935 | inferred from electronic annotation with InterPro:IPR005716 ribosome ; GO:0005840 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "RpS5, CG8922, rpS5, M(1)15D, RS5, M(1)o, M[[o]], M(1)34i28, RpS5a, rps5, S5a, Rp S5a, M(1)15d, RS5A_DROME" "IPR000235:Ribosomal protein S5/S7, IPR005716:Ribosomal protein S5/S7, eukaryotic/archaeal, IPR020606:Ribosomal protein S7, conserved site, IPR023798:Ribosomal protein S7 domain" CG8922 11-Aug-17 DroID_v2017_08 "Drer\zgc:153322, Drer\rps5, Drer\mrps7" "Scer\RPS5, Scer\RSM7" Cele\rps-5 "Xtro\mrps7, Xtro\rps5" "Mmus\Rps5, Mmus\Mrps7" "Hsap\MRPS7, Hsap\RPS5" "developmental rate defective,dominant,visible,Minute,size defective,lethal" "macrochaeta,adult heart" DRSC20282 EK -0.585595634 -0.575191348 0.17520749 -2.178272914 1.635791469 3.410494314 FBgn0266489 CG45088 - http://flybase.org/reports/FBgn0266489 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45088, Dromel_CG6191_FBtr0087678_uORF" - CG45088 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264775 CG44013 - http://flybase.org/reports/FBgn0264775 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14872, CG44013" IPR012674:Calycin CG44013 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005468 l(1)ts178 lethal (1) ts178 http://flybase.org/reports/FBgn0005468 - gene - - - l(1)ts178 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0062412 Ctr1B Copper transporter 1B http://flybase.org/reports/FBgn0062412 protein_coding_gene copper ion transmembrane transporter activity ; GO:0005375 | inferred from direct assay copper uptake transmembrane transporter activity ; GO:0015088 | inferred from mutant phenotype copper ion transmembrane transport ; GO:0035434 | inferred from electronic annotation with InterPro:IPR007274 copper ion transport ; GO:0006825 | inferred from mutant phenotype response to metal ion ; GO:0010038 | inferred from mutant phenotype copper ion transport ; GO:0006825 | inferred from direct assay cellular copper ion homeostasis ; GO:0006878 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007274 "CG7459, Ctr1B, ctr1B" IPR007274:Ctr copper transporter CG7459 11-Aug-17 DroID_v2017_08 "Drer\slc31a1, Drer\slc31a2" "Scer\CTR2, Scer\CTR3, Scer\CTR1" "Cele\Y58A7A.1, Cele\K12C11.6, Cele\K12C11.3, Cele\F58G6.9, Cele\F58G6.3, Cele\K12C11.7, Cele\F27C1.2, Cele\F58G6.7, Cele\F01G12.1, Cele\F31E8.4" "Xtro\slc31a2, Xtro\slc31a1" "Mmus\Slc31a2, Mmus\Slc31a1" "Hsap\SLC31A1, Hsap\SLC31A2" "visible,lethal,conditional,recessive,body color defective,chemical sensitive,partially lethal - majority die,viable" "eye,chemical conditional,adult cuticle,conditional" FBgn0260315 GSd410 - http://flybase.org/reports/FBgn0260315 gene - - - GSd410 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039886 CG2003 - http://flybase.org/reports/FBgn0039886 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 CG2003 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG2003 11-Aug-17 DroID_v2017_08 "Drer\slc17a8, Drer\slc17a7a, Drer\slc17a9a, Drer\slc17a5, Drer\slc17a6b, Drer\slc17a6a, Drer\ppt1, Drer\si:ch1073-513e17.1" "Scer\YIL166C, Scer\THI73, Scer\DAL5, Scer\TNA1" "Cele\T28H11.8, Cele\H11E01.2, Cele\C18H9.5, Cele\slc-17.1, Cele\M117.1, Cele\T22F3.11, Cele\T27D12.1, Cele\C01B4.8, Cele\T01H3.3, Cele\slc-17.4, Cele\T19D12.9, Cele\F56A4.10, Cele\T02B11.6, Cele\C39E9.7, Cele\slc-17.5, Cele\T22F3.7, Cele\F11A5.9, Cele\T22F3.8, Cele\C18D1.2, Cele\T19D12.10, Cele\Y19D10A.5, Cele\slc-17.8, Cele\Y19D10A.11, Cele\T22F3.10, Cele\Y19D10A.8, Cele\F59A1.13, Cele\F41C3.2, Cele\D1046.4, Cele\M162.5, Cele\C01B4.7, Cele\F44E7.7, Cele\slc-17.2, Cele\Y4C6B.3, Cele\K11G9.5, Cele\slc-17.3, Cele\Y19D10A.4, Cele\Y51B9A.6, Cele\R10D12.1, Cele\Y15E3A.4, Cele\F10C2.7, Cele\F56A4.12, Cele\K08C7.1, Cele\Y4C6B.4, Cele\C35A5.3, Cele\cima-1, Cele\W04C9.6, Cele\slc-17.9" Xtro\slc17a7 "Mmus\Slc17a7, Mmus\Slc17a5, Mmus\Slc17a3, Mmus\Slc17a1, Mmus\Slc17a8, Mmus\Slc17a6, Mmus\Slc17a2, Mmus\Slc17a4" "Hsap\SLC17A7, Hsap\SLC17A3, Hsap\SLC17A2, Hsap\SLC17A5, Hsap\SLC17A4, Hsap\SLC17A6, Hsap\SLC17A1, Hsap\SLC17A8" "mitotic cell cycle defective,viable" FBgn0032521 CG7110 - http://flybase.org/reports/FBgn0032521 protein_coding_gene - - - CG7110 - CG7110 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0036980 RhoBTB Rho-related BTB domain containing http://flybase.org/reports/FBgn0036980 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225" "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578 melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype" intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003578 cellular_component ; GO:0005575 | no biological data available "RhoBTB, RhoGTPase, CG5701, RhoX, 28574635" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003578:Small GTPase superfamily, Rho type" CG5701 11-Aug-17 DroID_v2017_08 "Drer\rhobtb1, Drer\rhoab, Drer\rhoj, Drer\rnd2, Drer\rac3b, Drer\rhogc, Drer\rhoac, Drer\rhoh, Drer\rhoca, Drer\rhobtb2a, Drer\rhocb, Drer\rac1l, Drer\cdc42l, Drer\rnd1b, Drer\si:dkey-6b12.5, Drer\si:dkey-263f15.2, Drer\rhobtb2b, Drer\rnd1a, Drer\si:ch211-133l11.10, Drer\rhoub, Drer\rhof, Drer\cdc42, Drer\rhoaa, Drer\rac3a, Drer\cdc42l2, Drer\rac1b, Drer\rnd3b, Drer\rhogb, Drer\rhoq, Drer\LOC100331257, Drer\rac1a, Drer\rhov, Drer\rhoua, Drer\rnd3a, Drer\rhoga" "Scer\RHO2, Scer\RHO3, Scer\RHO5, Scer\RHO1, Scer\CDC42, Scer\RHO4" - "Xtro\rhobtb2, Xtro\rhoa, Xtro\rhoj, Xtro\rhoa.2, Xtro\rhof, Xtro\rhov, Xtro\rhoc, Xtro\rhob, Xtro\rac1, Xtro\cdc42, Xtro\rhobtb1, Xtro\rhobtb3, Xtro\rnd1, Xtro\rnd3, Xtro\rac2, Xtro\rhou" "Mmus\Rhobtb2, Mmus\Rhog, Mmus\Rhoq, Mmus\Rhov, Mmus\Rhoh, Mmus\Rhob, Mmus\Rhobtb1, Mmus\4930544G11Rik, Mmus\Rac3, Mmus\Rnd1, Mmus\Rhou, Mmus\Rnd3, Mmus\Rac1, Mmus\Rhoa, Mmus\Rhoc, Mmus\Rhod, Mmus\Cdc42, Mmus\Rnd2, Mmus\Rhobtb3, Mmus\Rac2, Mmus\Rhof, Mmus\Rhoj" "Hsap\CDC42, Hsap\RAC3, Hsap\RHOBTB1, Hsap\RHOD, Hsap\RHOBTB2, Hsap\RHOBTB3, Hsap\RAC2, Hsap\RHOF, Hsap\RHOV, Hsap\RHOC, Hsap\RAC1, Hsap\RND2, Hsap\RND1, Hsap\RHOQ, Hsap\RND3, Hsap\RHOB, Hsap\RHOA, Hsap\RHOU, Hsap\RHOH, Hsap\RHOG, Hsap\RHOJ" immune response defective FBgn0261727 EC549 - http://flybase.org/reports/FBgn0261727 gene - - - EC549 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0085664 CR41519 - http://flybase.org/reports/FBgn0085664 pseudogene_attribute - - - "CG41519, CR41519" - CR41519 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058367 CG40367 - http://flybase.org/reports/FBgn0058367 protein_coding_gene - - - CG40367 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084021 CG41459 - http://flybase.org/reports/FBgn0084021 protein_coding_gene - - - CG41459 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060784 l(3)S059813 lethal (3) S059813 http://flybase.org/reports/FBgn0060784 gene - - - "0598/13, l(3)S059813" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038629 CG14304 - http://flybase.org/reports/FBgn0038629 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14304 IPR002557:Chitin binding domain CG14304 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - "viable,fertile" FBgn0060609 l(3)S090405b lethal (3) S090405b http://flybase.org/reports/FBgn0060609 gene - - - "0904/05, l(3)S090405b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001773 l(1)M47 lethal (1) M47 http://flybase.org/reports/FBgn0001773 - gene - - - l(1)M47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0267918 CR46199 - http://flybase.org/reports/FBgn0267918 non_protein_coding_gene - - - "CR46199, lincRNA.782" - CR46199 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051633 CG31633 - http://flybase.org/reports/FBgn0051633 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG13770, CG31633, FBXL17" "IPR032675:Leucine-rich repeat domain, L domain-like" CG31633 11-Aug-17 DroID_v2017_08 - - Cele\B0393.3 - - Hsap\FBXL4 FBgn0053110 CG33110 - http://flybase.org/reports/FBgn0053110 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "CG13844, CG6926, CG33110" IPR002076:ELO family CG33110 11-Aug-17 DroID_v2017_08 "Drer\elovl4b, Drer\zgc:101858, Drer\dhrs7, Drer\elovl1a, Drer\elovl8b, Drer\elovl1b, Drer\elovl5, Drer\elovl4a, Drer\elovl2, Drer\hsd17b8, Drer\elovl7a, Drer\elovl8a, Drer\elovl7b" "Scer\ELO1, Scer\ELO2, Scer\ELO3" "Cele\Y47G6A.22, Cele\ZK829.1, Cele\dhs-14, Cele\C06E4.3, Cele\Y47G6A.21, Cele\dhs-11, Cele\F26D2.15, Cele\F25D1.5, Cele\F28H7.2, Cele\dhs-25" "Xtro\elovl7, Xtro\elovl2, Xtro\MGC79752, Xtro\hsd17b8, Xtro\dhrs7, Xtro\elovl1, Xtro\cbr4, Xtro\elovl5" "Mmus\Elovl4, Mmus\Elovl2, Mmus\Dhrs7, Mmus\Elovl1, Mmus\Elovl7, Mmus\H2-Ke6, Mmus\Elovl5, Mmus\Cbr4" "Hsap\ELOVL7, Hsap\DHRS7, Hsap\ELOVL1, Hsap\CBR4, Hsap\HSD17B8, Hsap\ELOVL2, Hsap\ELOVL4, Hsap\ELOVL5" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263776 CG43693 - http://flybase.org/reports/FBgn0263776 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 "CG43693, CG6327, CG34239" "IPR013057:Amino acid transporter, transmembrane domain" CG43693 11-Aug-17 DroID_v2017_08 "Drer\slc36a4, Drer\slc36a1" "Scer\AVT3, Scer\AVT4" "Cele\F13H10.3, Cele\slc-36.2, Cele\Y43F4B.7, Cele\skat-1, Cele\slc-36.4, Cele\slc-36.3, Cele\slc-36.5" "Xtro\slc36a4, Xtro\slc36a1" "Mmus\Slc36a2, Mmus\Slc36a3, Mmus\Slc36a1, Mmus\Slc36a4" "Hsap\SLC36A4, Hsap\SLC36A3, Hsap\SLC36A1, Hsap\SLC36A2" FBgn0060882 l(3)S044835a lethal (3) S044835a http://flybase.org/reports/FBgn0060882 gene - - - "0448/35, l(3)S044835a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0052034 tRNA:Thr-AGT-3-1Psi transfer RNA:Threonine-AGT 3-1 pseudogene http://flybase.org/reports/FBgn0052034 pseudogene_attribute - - - "AE002602.trna15-ThrAGT, tRNA:TPsi:AGT:AE002602, CR32034, tRNA:CR32034, chr3L.trna21-ThrAGT, tRNA-Thr-AGT-3-1, tRNA:Thr-AGT-3-1Psi, tRNA:T:Psi" - CR32034 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014065 Su(tor)3-307 Su(tor)3-307 http://flybase.org/reports/FBgn0014065 - gene - - - Su(tor)3-307 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0023138 WppE White prepupal locus E http://flybase.org/reports/FBgn0023138 - gene - - - "7, 21, 14, WppE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067731 l(1)R-8-18 lethal (1) R-8-18 http://flybase.org/reports/FBgn0067731 gene - - - l(1)R-8-18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060802 l(3)S057114b lethal (3) S057114b http://flybase.org/reports/FBgn0060802 gene - - - "0571/14, l(3)S057114b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267477 CR45827 - http://flybase.org/reports/FBgn0267477 non_protein_coding_gene - - - CR45827 - CR45827 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060826 l(3)S051302 lethal (3) S051302 http://flybase.org/reports/FBgn0060826 gene - - - "0513/02, l(3)S051302" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0028699 Rh50 Rh50 http://flybase.org/reports/FBgn0028699 protein_coding_gene ammonium transmembrane transporter activity ; GO:0008519 | inferred from biological aspect of ancestor with PANTHER:PTN000198157 organic cation transport ; GO:0015695 | inferred from biological aspect of ancestor with PANTHER:PTN000198157 ammonium transmembrane transport ; GO:0072488 | inferred from biological aspect of ancestor with PANTHER:PTN000198157 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000198157 "Rh-like, CG7499, BcDNA:GH03016, Rh50" "IPR002229:Blood group Rhesus C/E/D polypeptide, IPR024041:Ammonium transporter AmtB-like domain" CG7499 11-Aug-17 DroID_v2017_08 "Drer\rhag, Drer\rhd, Drer\rhcgb, Drer\rhbg, Drer\rh50, Drer\rhcgl1, Drer\rhcga" Scer\MEP2 "Cele\rhr-2, Cele\rhr-1" "Xtro\rhag, Xtro\rhd, Xtro\rhcg, Xtro\rhbg" "Mmus\Rhbg, Mmus\Rhcg, Mmus\Rhag, Mmus\Rhd" "Hsap\RHAG, Hsap\RHBG, Hsap\RHD, Hsap\RHCE, Hsap\RHCG" viable FBgn0266748 CR45221 - http://flybase.org/reports/FBgn0266748 non_protein_coding_gene - - - CR45221 - CR45221 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015892 anon-84Fa T2 transcript http://flybase.org/reports/FBgn0015892 - gene - - - "T2, anon-84Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019776 l(1)32 lethal (1) 32 http://flybase.org/reports/FBgn0019776 - gene - - - l(1)32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034694 CG6613 - http://flybase.org/reports/FBgn0034694 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 - CG6613 "IPR025258:Putative zinc-RING and/or ribbon, IPR001841:Zinc finger, RING-type, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR004012:RUN domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6613 11-Aug-17 DroID_v2017_08 "Drer\rubcn, Drer\plekhm3, Drer\def8, Drer\plekhm1" - "Cele\F20H11.1, Cele\Y56A3A.16, Cele\Y51H1A.2" Xtro\plekhm3 "Mmus\Def8, Mmus\Rubcnl, Mmus\Plekhm3, Mmus\Plekhm1, Mmus\Rufy4, Mmus\Rubcn" "Hsap\RUFY4, Hsap\DEF8, Hsap\PLEKHM1, Hsap\RUBCNL, Hsap\PLEKHM3, Hsap\RUBCN" viable FBgn0041623 Or65c Odorant receptor 65c http://flybase.org/reports/FBgn0041623 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "CG32403, 65c, LU27.3, DOR65, Or65c" "IPR004117:Olfactory receptor, insect" CG32403 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035090 CG2736 - http://flybase.org/reports/FBgn0035090 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 lipid particle ; GO:0005811 | inferred from direct assay "CG2736, cg2736" IPR002159:CD36 family CG2736 11-Aug-17 DroID_v2017_08 "Drer\cd36, Drer\scarb1, Drer\scarb2, Drer\LOC564077" - "Cele\scav-3, Cele\scav-2, Cele\scav-1" "Xtro\cd36, Xtro\scarb2, Xtro\scarb1" "Mmus\Cd36, Mmus\Scarb2, Mmus\Scarb1" "Hsap\SCARB2, Hsap\SCARB1, Hsap\CD36" "viable,fertile" DRSC04314 E 0.488191256 0.053859534 1.534127731 -0.004317665 -0.416692636 -0.409543202 FBgn0263971 CG43725 - http://flybase.org/reports/FBgn0263971 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43725 - CG43725 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051363 Jupiter Jupiter http://flybase.org/reports/FBgn0051363 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 structural constituent of cytoskeleton ; GO:0005200 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from direct assay positive regulation of microtubule polymerization ; GO:0031116 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay microtubule ; GO:0005874 | colocalizes_with inferred from direct assay "CG17238, CG31363, CG18763, clone 1.76, BEST:LP05168, anon-EST:Liang-1.76, CG18762, BcDNA:RH53211, BcDNA:LD43690, BcDNA:LD21358, BcDNA:GH06373, anon-WO0140519.173, Jupiter, jupiter" "IPR013087:Zinc finger C2H2-type, IPR033335:Microtubule-associated protein Jupiter/Hematological and neurological expressed 1" CG31363 11-Aug-17 DroID_v2017_08 "Drer\hn1a, Drer\hn1b, Drer\hn1l" - - - "Mmus\Hn1l, Mmus\Hn1" "Hsap\HN1, Hsap\HN1L" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0083027 snoRNA:Psi18S-531 snoRNA:Psi18S-531 http://flybase.org/reports/FBgn0083027 snoRNA_gene - - - "snoRNA:Psi18S-531, Psi18S-531, psi18S-531, Psi 18S-531, CR34590, chrX:619903..620074" - CR34590 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027986 l(3)S132413 lethal (3) S132413 http://flybase.org/reports/FBgn0027986 gene - - - "1324/13, l(3)S132413" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260270 GSd454 - http://flybase.org/reports/FBgn0260270 gene - - - GSd454 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260744 Tango9 Transport and Golgi organization 9 http://flybase.org/reports/FBgn0260744 protein_coding_gene - protein secretion ; GO:0009306 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from sequence or structural similarity with UniProtKB:Q8N357 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ; GO:1901029 | inferred from sequence or structural similarity with UniProtKB:Q8N357 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012404 Golgi apparatus ; GO:0005794 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q8N357 "CG10007, TANGO9, Tango9, 87A7-9/5, anon-87Ad" IPR012404:Nucleotide-sugar transporter-related CG10007 11-Aug-17 DroID_v2017_08 Drer\slc35f6 Scer\YML018C Cele\C29H12.2 Xtro\slc35f6 Mmus\Slc35f6 "Hsap\SLC35F6, Hsap\CENPA" FBgn0004746 l(3)85Fc lethal (3) 85Fc http://flybase.org/reports/FBgn0004746 - gene - - - l(3)85Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065190 l(2)SH2334 lethal (2) SH2334 http://flybase.org/reports/FBgn0065190 gene - - - "l(2)SH2334, l(2)SH2 2334" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014227 l(2)31Ef lethal (2) 31Ef http://flybase.org/reports/FBgn0014227 - gene - - - "l(2)31Ef, 31Ef" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036781 CG13699 - http://flybase.org/reports/FBgn0036781 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13699 - CG13699 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0033864 CG18368 - http://flybase.org/reports/FBgn0033864 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18368 - CG18368 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0063493 GstE7 Glutathione S transferase E7 http://flybase.org/reports/FBgn0063493 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG17531, DmGSTE7, GstE7, GSTE7, GST-E7, gstE7, E7, gste7" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17531 11-Aug-17 DroID_v2017_08 "Drer\gstt1b, Drer\gstt1a, Drer\gstr, Drer\mars, Drer\gstt2, Drer\vars, Drer\eef1e1, Drer\eef1g" "Scer\GTT2, Scer\URE2, Scer\YGR201C, Scer\CAM1, Scer\TEF4, Scer\GTT1" "Cele\gst-21, Cele\gst-29" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Eef1e1, Mmus\Vars, Mmus\Gstt1, Mmus\Gstt4, Mmus\Eef1g, Mmus\Gstt3, Mmus\Gstt2, Mmus\Mars" "Hsap\VARS, Hsap\MARS, Hsap\EEF1G, Hsap\EEF1E1, Hsap\GSTT2B, Hsap\GSTT2, Hsap\GSTT1" "viable,fertile" FBgn0264707 RhoGEF3 Rho guanine nucleotide exchange factor 3 http://flybase.org/reports/FBgn0264707 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with GEFmeso regulation of Rho protein signal transduction ; GO:0035023 | inferred from sequence or structural similarity with GEFmeso melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG43976, CG1225, CG42378, RhoGEF3, RhoGEF, CG13883, DrhoGEF3, rhoGEF3, CG42377, CG13882, CG13881" "IPR000219:Dbl homology (DH) domain, IPR001452:SH3 domain, IPR011993:PH domain-like" CG43976 11-Aug-17 DroID_v2017_08 "Drer\spata13, Drer\arhgef9a, Drer\vav3b, Drer\prex1, Drer\arhgef9b, Drer\pex13, Drer\vav2, Drer\arhgef4" "Scer\CDC24, Scer\PEX13" "Cele\uig-1, Cele\prx-13, Cele\tiam-1, Cele\vav-1, Cele\Y37A1B.17" "Xtro\spata13, Xtro\arhgef4" "Mmus\Pex13, Mmus\Prex1, Mmus\Vav1, Mmus\Vav2, Mmus\Spata13, Mmus\Plekhg3, Mmus\Vav3, Mmus\Arhgef9, Mmus\Plekhg2, Mmus\Plekhg1, Mmus\Arhgef4" "Hsap\ARHGEF9, Hsap\PEX13, Hsap\SPATA13, Hsap\ARHGEF4, Hsap\VAV3, Hsap\PREX1, Hsap\VAV1, Hsap\VAV2, Hsap\PLEKHG1, Hsap\PLEKHG2, Hsap\PLEKHG3" FBgn0262595 CheA56a Chemosensory protein A 56a http://flybase.org/reports/FBgn0262595 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheA29a extracellular region ; GO:0005576 | inferred from sequence model "CheA56a, CG33724" IPR010512:Protein of unknown function DUF1091 CG33724 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262076 JC14 - http://flybase.org/reports/FBgn0262076 gene - response to anesthetic ; GO:0072347 | inferred from mutant phenotype - JC14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0035402 Usp5 Ubiquitin specific protease 5 http://flybase.org/reports/FBgn0035402 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001607 Lys48-specific deubiquitinase activity ; GO:1990380 | inferred from direct assay thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:12611 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype regulation of ubiquitin homeostasis ; GO:0010993 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype free ubiquitin chain depolymerization ; GO:0010995 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:12611 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of proteasome assembly ; GO:0090364 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype protein K48-linked deubiquitination ; GO:0071108 | inferred from direct assay inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG12082, DmUsp5, Usp5, leon, USP5, Q9VZU7, usp5" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR001607:Zinc finger, UBP-type, IPR009060:UBA-like, IPR018200:Ubiquitin specific protease, conserved site, IPR015940:Ubiquitin-associated domain, IPR016652:Ubiquitinyl hydrolase, IPR028889:Ubiquitin specific protease domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG12082 11-Aug-17 DroID_v2017_08 "Drer\usp5, Drer\usp13" Scer\UBP14 Cele\usp-5 "Xtro\usp5, Xtro\usp13" "Mmus\Usp5, Mmus\Usp13" "Hsap\USP5, Hsap\USP13" "lethal - all die before end of pupal stage,some die during pupal stage,locomotor behavior defective,short lived,visible" "wing,wing margin bristle,scutellar bristle" FBgn0040697 Teh3 tipE homolog 3 http://flybase.org/reports/FBgn0040697 protein_coding_gene sodium channel regulator activity ; GO:0017080 | inferred from direct assay regulation of sodium ion transport ; GO:0002028 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG18676, TEH3, Teh3" IPR031578:Na+ channel auxiliary subunit TipE CG18676 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030549 CG18637 - http://flybase.org/reports/FBgn0030549 protein_coding_gene - - - CG18637 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065487 l(2)SH1259 lethal (2) SH1259 http://flybase.org/reports/FBgn0065487 gene - - - l(2)SH1259 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013501 l(1)PB18 lethal (1) PB18 http://flybase.org/reports/FBgn0013501 - gene - - - l(1)PB18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,recessive,rescuable maternal effect" "dorsal closure embryo,germline clone" FBgn0040051 CG17402 - http://flybase.org/reports/FBgn0040051 protein_coding_gene - - - CG17402 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032242 CG5355 - http://flybase.org/reports/FBgn0032242 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR002470, InterPro:IPR002471, InterPro:IPR023302 serine-type exopeptidase activity ; GO:0070008 | inferred from electronic annotation with InterPro:IPR023302 carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001375, InterPro:IPR002470, InterPro:IPR002471" - CG5355 "IPR002470:Peptidase S9A, prolyl oligopeptidase, IPR002471:Peptidase S9, serine active site, IPR029058:Alpha/Beta hydrolase fold, IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR023302:Peptidase S9A, N-terminal domain" CG5355 11-Aug-17 DroID_v2017_08 "Drer\prep, Drer\prepl, Drer\zgc:136971, Drer\LOC101883320" - "Cele\dpf-6, Cele\dpf-4, Cele\dpf-5, Cele\dpf-1" "Xtro\prep, Xtro\prepl" "Mmus\Prep, Mmus\Prepl, Mmus\Apeh" "Hsap\DPP10, Hsap\FAP, Hsap\PREPL, Hsap\PREP, Hsap\DPP4, Hsap\APEH" viable FBgn0027934 alpha-Est4aPsi alpha-Est4aPsi http://flybase.org/reports/FBgn0027934 pseudogene_attribute - - - "DmalphaE4a-Psi, alphaE4a-Psi, alphaE4, aE4a, alphaEPsi, CR31511, alpha-EstPsi, alpha-Est4aPsi" - CR31511 11-Aug-17 DroID_v2017_08 - - - - - - DRSC12473 E 0.229846143 0.549824274 1.601292715 0.556970792 0.125857508 -0.35404361 FBgn0014192 hrp hyperpolarizing receptor potential http://flybase.org/reports/FBgn0014192 - gene - - - hrp - - 11-Aug-17 DroID_v2017_08 - - - - - - "visual behavior defective,recessive,neurophysiology defective" retina FBgn0038567 CG14316 - http://flybase.org/reports/FBgn0038567 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14316 "IPR032675:Leucine-rich repeat domain, L domain-like" CG14316 11-Aug-17 DroID_v2017_08 - - Cele\K05C4.9 - - - viable FBgn0086251 del deadlock http://flybase.org/reports/FBgn0086251 protein_coding_gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype fusome organization ; GO:0045478 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "del, CG9252, Del" - CG9252 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035873 CG13670 - http://flybase.org/reports/FBgn0035873 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model CG13670 "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG13670 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0028539 CG31731 - http://flybase.org/reports/FBgn0028539 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity transporter activity ; GO:0005215 | inferred from sequence or structural similarity" lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 plasma membrane ; GO:0005886 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 "CG7491, DS00797.5, D00797.5, BG:DS00797.5, CG7559, CG31731" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR026082:ABC transporter A, ABCA" CG31731 11-Aug-17 DroID_v2017_08 "Drer\abca1a, Drer\abca1b, Drer\abca12, Drer\abca3b, Drer\abca2, Drer\abca5, Drer\abch1" - "Cele\abt-1, Cele\abt-4, Cele\abt-5, Cele\ced-7, Cele\abt-2" "Xtro\abca8, Xtro\abca4, Xtro\abca1, Xtro\abca10, Xtro\abca2, Xtro\abca9, Xtro\abca3" "Mmus\Abca1, Mmus\Abca2, Mmus\Abca14, Mmus\Abca12, Mmus\Abca15, Mmus\Abca6, Mmus\Abca8b, Mmus\Abca5, Mmus\Abca7, Mmus\Abca16, Mmus\Abca9, Mmus\Abca3, Mmus\Abca13, Mmus\Abca17, Mmus\Abca4, Mmus\Abca8a" "Hsap\ABCA7, Hsap\ABCA12, Hsap\ABCA8, Hsap\ABCA2, Hsap\ABCA6, Hsap\ABCA10, Hsap\ABCA9, Hsap\ABCA1, Hsap\ABCA5, Hsap\ABCA3, Hsap\ABCA13, Hsap\ABCA4" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0259975 Sfp87B Seminal fluid protein 87B http://flybase.org/reports/FBgn0259975 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp87B, CG42485, GH21617p" - CG42485 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033926 Arc1 Activity-regulated cytoskeleton associated protein 1 http://flybase.org/reports/FBgn0033926 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 muscle system process ; GO:0003012 | inferred from expression pattern inferred from genetic interaction with Mhc behavioral response to starvation ; GO:0042595 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay sarcomere ; GO:0030017 | inferred from direct assay "anon-WO0153538.45, anon-WO0153538.43, anon-WO0153538.41, anon-WO0153538.40, anon-WO0153538.31, Arc1, dARC1, CG12505, dArc1, arc1, Arc" "IPR001878:Zinc finger, CCHC-type" CG12505 11-Aug-17 DroID_v2017_08 "Drer\zgc:113436, Drer\oard1" - "Cele\F54G2.2, Cele\fbxb-37, Cele\W08F4.12" - "Mmus\Arc, Mmus\Oard1" "Hsap\OARD1, Hsap\ARC" "viable,stress response defective,locomotor behavior defective" DRSC06159 IE -1.510182251 -4.046908545 -1.868193057 -1.047997169 -0.312952371 -0.219528614 FBgn0027639 mei-T3 mei-T3 http://flybase.org/reports/FBgn0027639 - gene molecular_function ; GO:0003674 | no biological data available female meiotic division ; GO:0007143 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mei-T3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,meiotic cell cycle defective,female" FBgn0004444 prd11 paired-like 11 http://flybase.org/reports/FBgn0004444 - gene - - - prd11 - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | <8-12 hr , oogenesis stage " FBgn0040101 lectin-24Fa lectin-24Fa http://flybase.org/reports/FBgn0040101 gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity - - "AC004373a, AC 004373A, lectin-24Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250904 CG34434 - http://flybase.org/reports/FBgn0250904 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34434, CG15780, CG17763" - CG34434 11-Aug-17 DroID_v2017_08 "Drer\myl1, Drer\mylz3, Drer\myl6, Drer\myl4, Drer\cmlc1, Drer\myl13, Drer\zgc:153867, Drer\zgc:163073" - - "Xtro\myl4, Xtro\myl1, Xtro\myl6, Xtro\myl3" "Mmus\Myl6b, Mmus\Myl1, Mmus\Myl3, Mmus\Myl6, Mmus\Myl4" "Hsap\MYL1, Hsap\MYL6, Hsap\MYL6B, Hsap\MYL4, Hsap\MYL3" FBgn0001128 Gpdh Glycerol 3 phosphate dehydrogenase http://flybase.org/reports/FBgn0001128 - protein_coding_gene "glycerol-3-phosphate dehydrogenase [NAD+] activity ; GO:0004367 | inferred from electronic annotation with InterPro:IPR006109, InterPro:IPR006168, InterPro:IPR017751 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR011128, InterPro:IPR017751 protein homodimerization activity ; GO:0042803 | inferred from electronic annotation with InterPro:IPR017751" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006109 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006109, InterPro:IPR006168, InterPro:IPR008927, InterPro:IPR011128, InterPro:IPR013328, InterPro:IPR017751 glycerol-3-phosphate catabolic process ; GO:0046168 | inferred from electronic annotation with InterPro:IPR011128 ethanol metabolic process ; GO:0006067 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype triglyceride metabolic process ; GO:0006641 | inferred from mutant phenotype response to hyperoxia ; GO:0055093 | inferred from mutant phenotype" glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR006168 M band ; GO:0031430 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Gpdh, alpha-Gpdh, alpha-GPD, CG9042, alphaGpdh, GPDH, gpdh, DROGPDHA, GPDA, alpha-GPDH-1, alphaGPDH, alpha-GPDH, Gpd, alphaGpdh-1, sn-Gpdh, alphaGpd, GPD, GAPDH, Gdh, G3pdh, G3PDH, GPDH-1, DmG3PDH, gpdh-1, dGpdh" "IPR006109:Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal, IPR006168:Glycerol-3-phosphate dehydrogenase, NAD-dependent, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR011128:Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal, IPR013328:6-phosphogluconate dehydrogenase, domain 2, IPR016040:NAD(P)-binding domain, IPR017751:Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic" CG9042 11-Aug-17 DroID_v2017_08 "Drer\gpd1a, Drer\gpd1l, Drer\gpd1c, Drer\gpd1b" "Scer\GPD1, Scer\GPD2" "Cele\gpdh-1, Cele\gpdh-2" "Xtro\gpd1, Xtro\gpd1l" "Mmus\Gpd1l, Mmus\Gpd1" "Hsap\GPD1, Hsap\GPD1L" " larval stage && adult stage , adult stage " "electrophoretic variant,viable,reduced,fertile,fast,lethal,recessive,flightless,flight defective,dominant,short lived,slow" embryonic/larval hemocyte | third instar larval stage FBgn0264283 Su(Mir)2E2-3 - http://flybase.org/reports/FBgn0264283 gene - - - Su(Mir)2E2-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267227 CR45667 - http://flybase.org/reports/FBgn0267227 non_protein_coding_gene - - - CR45667 - CR45667 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043566 Su(hh)I Su(hh)I http://flybase.org/reports/FBgn0043566 gene - - - Su(hh)I - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019799 l(1)06 lethal (1) 06 http://flybase.org/reports/FBgn0019799 - gene - - - l(1)06 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003631 Su(var)325 Suppressor of variegation 325 http://flybase.org/reports/FBgn0003631 - gene - - - Su(var)325 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant" FBgn0037529 mRpS9 mitochondrial ribosomal protein S9 http://flybase.org/reports/FBgn0037529 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82933 "mitochondrial translation ; GO:0032543 | traceable author statement maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000490829 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82933" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82933 "CG2957, MRP-S9, mRpS9" "IPR000754:Ribosomal protein S9, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold" CG2957 11-Aug-17 DroID_v2017_08 Drer\mrps9 Scer\MRPS9 Cele\mrps-9 Xtro\mrps9 Mmus\Mrps9 Hsap\MRPS9 "viable,visible" trichogen cell DRSC15456 K -0.26411989 -0.377855405 0.057366662 0.109386816 1.768465959 -1.366362362 FBgn0043488 fs(3)66EFb fs(3)66EFb http://flybase.org/reports/FBgn0043488 gene - - - fs(3)66EFb - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0060529 l(3)S101504 lethal (3) S101504 http://flybase.org/reports/FBgn0060529 gene - - - "1015/04, l(3)S101504" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060590 l(3)S093501b lethal (3) S093501b http://flybase.org/reports/FBgn0060590 gene - - - "0935/01, l(3)S093501b, l(3)s093501" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0064182 h::brk h::brk http://flybase.org/reports/FBgn0064182 engineered_fusion_gene - - - h::brk - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female,lethal" FBgn0024726 Su(var)13T Su(var)13T http://flybase.org/reports/FBgn0024726 - gene - - - Su(var)13T - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant" FBgn0086542 MRE10 mRNA-like ncRNA in embryogenesis 10 http://flybase.org/reports/FBgn0086542 non_protein_coding_gene - - - "MRE10, GM08676" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053927 CG33927 - http://flybase.org/reports/FBgn0053927 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33927 IPR010512:Protein of unknown function DUF1091 CG33927 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0022174 l(2)k05420 lethal (2) k05420 http://flybase.net/reports/FBgn0022174.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0040572 CG17201 - http://flybase.org/reports/FBgn0040572 protein_coding_gene - - - CG17201 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065208 l(2)SH2271 lethal (2) SH2271 http://flybase.org/reports/FBgn0065208 gene - - - "l(2)SH2271, l(2)SH2 2271" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002556 lme lame http://flybase.org/reports/FBgn0002556 - gene - - - lme - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,tarsal segment,wing" FBgn0067644 sunny-side-up sunny side up http://flybase.org/reports/FBgn0067644 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sunny-side-up - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0026743 anon-45Aa anon-45Aa http://flybase.org/reports/FBgn0026743 - gene - - - "CLOT3064, anon-45Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032178 Spn31A Serpin 31A http://flybase.org/reports/FBgn0032178 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues - extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "Spn31A, CG4804" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG4804 11-Aug-17 DroID_v2017_08 "Drer\serpinh1a, Drer\serpine1, Drer\serpinc1, Drer\serpinb1, Drer\serpinb1l1, Drer\serpine3, Drer\serpinh2, Drer\serpinb1l3, Drer\serpinh1b, Drer\serpinb1l4, Drer\si:ch1073-416d2.3, Drer\serpina10a, Drer\zgc:173729, Drer\serpinb1l2, Drer\serpine2" - "Cele\srp-2, Cele\srp-1" - "Mmus\Serpinb6c, Mmus\Serpinb3a, Mmus\Serpinb9d, Mmus\Serping1, Mmus\Gm11397, Mmus\Serpinb1b, Mmus\Serpinh1, Mmus\Serpinb6a, Mmus\Serpinb3c, Mmus\Serpinb9g, Mmus\Serpinb11, Mmus\Serpinb9c, Mmus\Serpinc1, Mmus\Serpinb5, Mmus\Serpinb9b, Mmus\Serpina10, Mmus\Serpinb10, Mmus\Serpinb2, Mmus\Serpinb12, Mmus\Serpinb6e, Mmus\Serpinb1c, Mmus\Serpine1, Mmus\Serpine3, Mmus\Serpina1d, Mmus\Serpinb6b, Mmus\Serpinb9, Mmus\Serpina1e, Mmus\Serpinb9f, Mmus\Serpinb9e, Mmus\Serpinb3b, Mmus\Serpine2, Mmus\Serpinb8, Mmus\Serpinb1a, Mmus\Serpinb6d, Mmus\Serpinb3d, Mmus\Serpinb13" "Hsap\SERPINB10, Hsap\HMSD, Hsap\SERPINA10, Hsap\SERPINE3, Hsap\SERPING1, Hsap\SERPINB12, Hsap\SERPINB13, Hsap\SERPINB11, Hsap\SERPINB9, Hsap\SERPINE2, Hsap\SERPINB8, Hsap\SERPINB2, Hsap\SERPINB6, Hsap\SERPINH1, Hsap\SERPINB1, Hsap\SERPINC1, Hsap\SERPINB3, Hsap\SERPINB4, Hsap\SERPINB5, Hsap\SERPINE1" viable FBgn0267048 CG45492 - http://flybase.org/reports/FBgn0267048 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45492 - CG45492 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259361 EP-709 - http://flybase.org/reports/FBgn0259361 gene - - - EP-709 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0004033 xwh extra wing hairs http://flybase.org/reports/FBgn0004033 - gene - - - xwh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027999 l(3)S121910b lethal (3) S121910b http://flybase.org/reports/FBgn0027999 gene - - - "1219/10, l(3)S121910, l(3)S121910b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001679 l(1)ER lethal (1) ER http://flybase.org/reports/FBgn0001679 - gene - - - "l(1)ER[ts], l(1)ER" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" "nucleus | embryonic stage,yolk" FBgn0053626 CG33626 - http://flybase.org/reports/FBgn0053626 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33626 IPR010512:Protein of unknown function DUF1091 CG33626 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264433 CG43851 - http://flybase.org/reports/FBgn0264433 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43851 "IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone" CG43851 11-Aug-17 DroID_v2017_08 - Scer\HSP26 - - - - FBgn0034059 CG8320 - http://flybase.org/reports/FBgn0034059 protein_coding_gene - vacuolar protein processing ; GO:0006624 | inferred from biological aspect of ancestor with PANTHER:PTN000337666 - CG8320 IPR008506:SRP-independent targeting protein 2/TMEM208 CG8320 11-Aug-17 DroID_v2017_08 Drer\zgc:77041 Scer\ENV10 Cele\R05D11.5 Xtro\tmem208 Mmus\Tmem208 Hsap\TMEM208 FBgn0000030 AcpC Accessory gland protein C http://flybase.org/reports/FBgn0000030 - gene - - - AcpC - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0052668 CG32668 - http://flybase.org/reports/FBgn0052668 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32668 "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR000225:Armadillo" CG32668 11-Aug-17 DroID_v2017_08 Drer\armc2 - - Xtro\armc2 Mmus\Armc2 Hsap\ARMC2 viable FBgn0267141 CR45581 - http://flybase.org/reports/FBgn0267141 non_protein_coding_gene - - - CR45581 - CR45581 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062583 Mod(var)224 Mod(var)224 http://flybase.org/reports/FBgn0062583 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "224, Mod(var)224" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0023064 l(1)20Cc lethal (1) 20Cc http://flybase.org/reports/FBgn0023064 - gene - - - "C2/5.5, l(1)20Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016833 l(1)MZ20 lethal (1) MZ20 http://flybase.org/reports/FBgn0016833 - gene - - - "l(1)MZ20, M20" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014971 l(1)13Fa lethal (1) 13Fa http://flybase.org/reports/FBgn0014971 - gene - - - "V, l(1)V, l(1)13Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000920 fs(1)ne7 female sterile (1) no eggs 7 http://flybase.org/reports/FBgn0000920 - gene - - - "ne7, fs(1)ne[7], fs(1)ne7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "dorsal appendage,chorion,oocyte" FBgn0025366 Ip259 Intronic Protein 259 http://flybase.org/reports/FBgn0025366 FBgn0064114 protein_coding_gene - maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000291059 phagocytosis ; GO:0006909 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000291059 "nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000291059 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000291059" "CG5277, IP259, Ip259" IPR022309:Ribosomal protein S8e/ribosomal biogenesis NSA2 CG5277 11-Aug-17 DroID_v2017_08 Drer\nsa2 Scer\NSA2 Cele\W09C5.1 Xtro\nsa2 Mmus\Nsa2 Hsap\NSA2 "lethal,recessive,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC03352 E -0.682671689 -0.815977117 1.63757639 -1.744638167 -0.505634386 0.046446407 FBgn0085693 CG41562 - http://flybase.org/reports/FBgn0085693 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 "small-subunit processome assembly ; GO:0034462 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000480 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000472 | inferred from biological aspect of ancestor with PANTHER:PTN000267771" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 CG41562 "IPR000504:RNA recognition motif domain, IPR034353:ABT1/ESF2, RNA recognition motif" CG41562 11-Aug-17 DroID_v2017_08 Drer\abt1 Scer\ESF2 Cele\F57B10.8 Xtro\abt1 Mmus\Abt1 Hsap\ABT1 FBgn0028327 l(1)G0320 lethal (1) G0320 http://flybase.org/reports/FBgn0028327 protein_coding_gene - cotranslational protein targeting to membrane ; GO:0006613 | inferred from biological aspect of ancestor with PANTHER:PTN000309014 endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR005595 lipid particle ; GO:0005811 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG32701, l(1)G0320, CG2994" "IPR005595:Translocon-associated protein (TRAP), alpha subunit" CG32701 11-Aug-17 DroID_v2017_08 Drer\ssr1 - Cele\trap-1 Xtro\ssr1 Mmus\Ssr1 Hsap\SSR1 "viable,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0004821 fs(2)ltoRM7 female sterile (2) ltoRM7 http://flybase.org/reports/FBgn0004821 - gene molecular_function ; GO:0003674 | no biological data available ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoRM7 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0051440 CG31440 - http://flybase.org/reports/FBgn0051440 protein_coding_gene - - - CG31440 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267491 Mst77Y-13 Male-specific transcript 77Y 13 http://flybase.org/reports/FBgn0267491 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F "Mst77Y-13, CG45767, MST77Y" - CG45767 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039808 CG12071 - http://flybase.org/reports/FBgn0039808 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 phagocytosis ; GO:0006909 | inferred from mutant phenotype - CG12071 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG12071 11-Aug-17 DroID_v2017_08 - "Scer\CMR3, Scer\MIG1" - - "Mmus\Zfp105, Mmus\Zscan26, Mmus\Zfp459" "Hsap\ZNF660, Hsap\ZSCAN26, Hsap\ZNF35" FBgn0026386 Or47a Odorant receptor 47a http://flybase.org/reports/FBgn0026386 - protein_coding_gene "transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model olfactory receptor activity ; GO:0004984 | inferred from direct assay olfactory receptor activity ; GO:0004984 | non-traceable author statement inferred by curator from GO:0004888,GO:0007608 olfactory receptor activity ; GO:0004984 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b" sensory perception of smell ; GO:0007608 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred by curator from GO:0004984 sensory perception of smell ; GO:0007608 | inferred from expression pattern detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "47a, DOR24, CG13225, AN10, 47E.1, dor24, DOR47E.1, Or47E.1, Or24, Or47a, OR47a, or47a" "IPR004117:Olfactory receptor, insect" CG13225 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,smell perception defective" large sensillum basiconicum of antennal segment 3 & olfactory neuronOr22a.8197 FBgn0264843 CR44051 - http://flybase.org/reports/FBgn0264843 non_protein_coding_gene - - - CR44051 - CR44051 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034938 CG3803 - http://flybase.org/reports/FBgn0034938 protein_coding_gene "oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from electronic annotation with InterPro:IPR003780" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003780 heme a biosynthetic process ; GO:0006784 | inferred from electronic annotation with InterPro:IPR003780 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR003780 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000590786 CG3803 "IPR003780:COX15/CtaA family, IPR009003:Peptidase S1, PA clan" CG3803 11-Aug-17 DroID_v2017_08 "Drer\fdx1, Drer\cox15, Drer\fdx1l" "Scer\COX15, Scer\YAH1" "Cele\Y73F8A.27, Cele\cox-15" "Xtro\fdx1, Xtro\cox15" "Mmus\Fdx1, Mmus\Fdx1l, Mmus\Cox15" "Hsap\COX15, Hsap\FDX1L, Hsap\FDX1" viable FBgn0024656 l(2)k07822 lethal (2) k07822 http://flybase.org/reports/FBgn0024656 - gene - - - "78/22, l(2)k07822" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,wing,wing vein" FBgn0004980 Bubble Bubble http://flybase.org/reports/FBgn0004980 - gene - - - "Bb, Bubble" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,male sterile" wing FBgn0086252 M(2)56i Minute (2) 56i http://flybase.org/reports/FBgn0086252 gene - - - M(2)56i - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004150 l(2)57Ad lethal (2) 57Ad http://flybase.org/reports/FBgn0004150 - gene - - - l(2)57Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034963 Not11 CCR4-NOT transcription complex subunit 11 http://flybase.org/reports/FBgn0034963 protein_coding_gene - negative regulation of translation ; GO:0017148 | inferred from direct assay mRNA catabolic process ; GO:0006402 | inferred from direct assay CCR4-NOT complex ; GO:0030014 | inferred from direct assay "CG13567, C2orf29, NOT11, Not11" IPR019312:CCR4-NOT transcription complex subunit 11 CG13567 11-Aug-17 DroID_v2017_08 Drer\cnot11 - Cele\ntl-11 Xtro\cnot11 Mmus\Cnot11 Hsap\CNOT11 "partially lethal - majority die,some die during pupal stage" FBgn0023157 Su(mg)2-2 Suppressor of modifier of gypsy 2-2 http://flybase.org/reports/FBgn0023157 - gene - - - Su(mg)2-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "eye,macrochaeta" FBgn0026651 l(2)46F4 lethal (2) 46F4 http://flybase.org/reports/FBgn0026651 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)46F4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0034785 CG3649 - http://flybase.org/reports/FBgn0034785 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 CG3649 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG3649 11-Aug-17 DroID_v2017_08 "Drer\ppt1, Drer\si:ch1073-513e17.1, Drer\slc17a8, Drer\slc17a9a, Drer\slc17a7a, Drer\slc17a5, Drer\slc17a6b, Drer\slc17a6a" "Scer\DAL5, Scer\TNA1, Scer\YIL166C, Scer\THI73" "Cele\K08C7.1, Cele\cima-1, Cele\Y19D10A.11, Cele\T22F3.11, Cele\F56A4.10, Cele\T22F3.8, Cele\T02B11.6, Cele\slc-17.9, Cele\F11A5.9, Cele\Y4C6B.3, Cele\C18D1.2, Cele\Y15E3A.4, Cele\Y19D10A.5, Cele\H11E01.2, Cele\C01B4.8, Cele\M117.1, Cele\slc-17.5, Cele\Y51B9A.6, Cele\T27D12.1, Cele\slc-17.8, Cele\T19D12.10, Cele\F59A1.13, Cele\D1046.4, Cele\slc-17.3, Cele\Y4C6B.4, Cele\F41C3.2, Cele\eat-4, Cele\slc-17.2, Cele\vglu-3, Cele\W04C9.6, Cele\K11G9.5, Cele\C35A5.3, Cele\T28H11.8, Cele\T01H3.3, Cele\C39E9.7, Cele\M162.5, Cele\slc-17.1, Cele\F10C2.7, Cele\R10D12.1, Cele\C18H9.5, Cele\vglu-2, Cele\T19D12.9, Cele\slc-17.4, Cele\T22F3.10, Cele\F44E7.7, Cele\Y19D10A.4, Cele\C01B4.7, Cele\F56A4.12, Cele\Y19D10A.8, Cele\T22F3.7" Xtro\slc17a7 "Mmus\Slc17a8, Mmus\Slc17a7, Mmus\Slc17a2, Mmus\Slc17a1, Mmus\Slc17a6, Mmus\Slc17a4, Mmus\Slc17a3, Mmus\Slc17a5" "Hsap\SLC17A2, Hsap\SLC17A3, Hsap\SLC17A5, Hsap\SLC17A6, Hsap\SLC17A1, Hsap\SLC17A7, Hsap\SLC17A8, Hsap\SLC17A4" viable FBgn0004591 Eig71Ed Ecdysone-induced gene 71Ed http://flybase.org/reports/FBgn0004591 FBgn0063120 protein_coding_gene - salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 extracellular region ; GO:0005576 | inferred from sequence model "L71, L71-4, IV, gene IV, gene-IV, CG7350, BcDNA:LP04160, Eig71Ed, Eig 71Ed" IPR003475:Insect protein of unknown function CG7350 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052026 CG32026 - http://flybase.org/reports/FBgn0052026 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR019818 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR019818 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR019818, InterPro:IPR024084" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR019818, InterPro:IPR024084" microtubule associated complex ; GO:0005875 | inferred from direct assay "BcDNA:GH12815, anon-WO0140519.202, CG32026" "IPR024084:Isopropylmalate dehydrogenase-like domain, IPR019818:Isocitrate/isopropylmalate dehydrogenase, conserved site" CG32026 11-Aug-17 DroID_v2017_08 Drer\idh3a "Scer\LEU2, Scer\IDH2, Scer\LYS12" Cele\idha-1 Xtro\idh3a Mmus\Idh3a Hsap\IDH3A viable FBgn0014173 fs(3)96A-96B fs(3)96A-96B http://flybase.org/reports/FBgn0014173 - gene - - - fs(3)96A-96B - - 11-Aug-17 DroID_v2017_08 - - - - - - female semi-sterile FBgn0259613 B0699 - http://flybase.org/reports/FBgn0259613 gene - - - B0699 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,unguis,tarsal segment,antennal segment,arista" FBgn0036716 CG13728 - http://flybase.org/reports/FBgn0036716 protein_coding_gene - - - CG13728 IPR015943:WD40/YVTN repeat-like-containing domain CG13728 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010069 M(3)bb Minute (3) bb http://flybase.org/reports/FBgn0010069 - gene - - - "M(3)[bb], M(3)bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,visible" macrochaeta FBgn0035426 CG12078 - http://flybase.org/reports/FBgn0035426 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with HGNC:19085 phosphoprotein phosphatase activity ; GO:0004721 | inferred from biological aspect of ancestor with PANTHER:PTN000258719 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:19085 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:19085 "CG12078, 24656659" "IPR004274:FCP1 homology domain, IPR011948:Dullard phosphatase domain, eukaryotic, IPR023214:HAD-like domain" CG12078 11-Aug-17 DroID_v2017_08 "Drer\ctdsp1, Drer\ctdspla, Drer\ctdnep1a, Drer\ctdsplb, Drer\ctdsp2, Drer\ublcp1, Drer\ctdnep1b, Drer\ctdspl2b, Drer\ctdspl2a, Drer\ctdspl3" "Scer\FCP1, Scer\PSR2, Scer\PSR1, Scer\NEM1" "Cele\fcp-1, Cele\cnep-1" "Xtro\ublcp1, Xtro\ctdsp2, Xtro\ctdspl, Xtro\ctdsp1, Xtro\ctdnep1, Xtro\ctdspl2" "Mmus\Ctdnep1, Mmus\Ctdsp1, Mmus\Ctdspl, Mmus\Ublcp1, Mmus\Ctdp1, Mmus\Ctdsp2, Mmus\Ctdspl2" "Hsap\CTDP1, Hsap\CTDSP1, Hsap\CTDSP2, Hsap\CTDSPL2, Hsap\CTDSPL, Hsap\UBLCP1, Hsap\CTDNEP1" viable FBgn0261455 scaRNA:MeU5-G38 small Cajal body-specific RNA : MeU5-G38 http://flybase.org/reports/FBgn0261455 snoRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "mgU5-38, scaRNA:pit-a, scaRNA:mgU5-38, scaRNA:MeU5-G38" - CR43572 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039338 XNP XNP http://flybase.org/reports/FBgn0039338 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 ATPase activity ; GO:0016887 | inferred from direct assay chromosome organization ; GO:0051276 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype regulation of JNK cascade ; GO:0046328 | inferred from genetic interaction with hep intrinsic apoptotic signaling pathway ; GO:0097193 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype DNA replication-independent nucleosome assembly ; GO:0006336 | inferred from mutant phenotype "polytene chromosome ; GO:0005700 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay beta-heterochromatin ; GO:0005722 | inferred from direct assay germinal vesicle ; GO:0042585 | inferred from direct assay" "xnp/atr-x, EP(3)0635, EP635, CG4548, XNP, DATR-X, ATR-X/XNP, dXNP, dATRX, DATRX, xnp, Xnp, atrx" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4548 11-Aug-17 DroID_v2017_08 "Drer\rad54l2, Drer\atrx" Scer\RAD54 "Cele\xnp-1, Cele\rad-26" "Xtro\atrx, Xtro\rad54l2" "Mmus\Atrx, Mmus\Rad54l2" "Hsap\DNMT3B, Hsap\ATRX, Hsap\RAD54L2" "neuroanatomy defective,viable,fertile,suppressor of variegation,dominant,partially lethal - majority die,recessive,visible,lethal" "longitudinal connective,interface glial cell,embryonic/larval glial cell,Kenyon cell,adult mushroom body,scutellum,adult thorax,microchaeta,anterior commissure,posterior commissure" FBgn0027943 pru perugino http://flybase.org/reports/FBgn0027943 gene - - - pru - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040958 Peritrophin-15b Peritrophin-15b http://flybase.org/reports/FBgn0040958 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from sequence or structural similarity chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular space ; GO:0005615 | inferred from sequence or structural similarity "Dm15b, CG13395, CG31893, Peritrophin-15b, Peritrophi-15b" IPR002557:Chitin binding domain CG31893 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0250843 Prosalpha6 Proteasome alpha6 subunit http://flybase.org/reports/FBgn0250843 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0000502" ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR000426 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0000502 ventral furrow formation ; GO:0007370 | inferred from mutant phenotype "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426 nucleus ; GO:0005634 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay" "pros35, CG4904, 143314_at, PROS-35, alpha_dm, PROS-Dm35, Pros-Dm35, anon-SAGE:Wang-116, pros 35, PSMA1, Prosalpha6, Pros-35, Alpha-6, Pros35, alpha6, alpha-6" "IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR023332:Proteasome alpha-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG4904 11-Aug-17 DroID_v2017_08 Drer\psma1 Scer\PRE5 Cele\pas-6 Xtro\psma1 Mmus\Psma1 Hsap\PSMA1 DRSC03401 IE -2.2742969 -2.664140861 -1.395674873 -2.40272079 -0.36722362 0.839614359 FBgn0003268 rod rough deal http://flybase.org/reports/FBgn0003268 FBgn0044458 protein_coding_gene "Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab18 protein binding ; GO:0005515 | inferred from physical interaction with Zw10, Zwilch" Golgi organization ; GO:0007030 | inferred from mutant phenotype protein localization to kinetochore ; GO:0034501 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | non-traceable author statement mitotic spindle assembly checkpoint ; GO:0007094 | traceable author statement "kinetochore microtubule ; GO:0005828 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay RZZ complex ; GO:1990423 | inferred from direct assay kinetochore microtubule ; GO:0005828 | non-traceable author statement RZZ complex ; GO:1990423 | inferred from physical interaction with Zw10, Zwilch condensed chromosome outer kinetochore ; GO:0000940 | non-traceable author statement Golgi stack ; GO:0005795 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay acroblast ; GO:0036063 | inferred from direct assay" "ROD, CG1569, EP3408, pNB20A, rod, Rod" "IPR019527:RZZ complex, subunit KNTC1/ROD, C-terminal" CG1569 11-Aug-17 DroID_v2017_08 Drer\kntc1 - Cele\rod-1 Xtro\kntc1 Mmus\Kntc1 Hsap\KNTC1 " larval stage | third instar , larval stage , spermatogenesis && adult stage " " neuroblast &&of larval brain

, larval brain

, spermatocyte

" "visible,viable,fertile,lethal - all die before end of larval stage,recessive,some die during larval stage,reduced,mitotic cell cycle defective,wild-type,lethal,partially lethal - majority live" "eye,intersegmental nerve,nuclear chromosome & mitotic anaphase,chromatin & mitotic anaphase,chromatin & mitotic telophase,mitotic anaphase,Golgi stack,acroblast,spermatocyte,meiotic cell cycle,neuroblast,nuclear chromosome,trichogen cell" FBgn0083115 W36 W36 http://flybase.org/reports/FBgn0083115 gene - - - W36 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "wing,wing vein L5" FBgn0028423 JhI-4 JhI-4 http://flybase.org/reports/FBgn0028423 gene - - - JhI-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005539 l(3)72Dg lethal (3) 72Dg http://flybase.org/reports/FBgn0005539 - gene - - - l(3)72Dg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015497 l(3)65CEa lethal (3) 65CEa http://flybase.org/reports/FBgn0015497 - gene - - - "X, l(3)65CEa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260374 GSd034 - http://flybase.org/reports/FBgn0260374 gene - - - GSd034 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,segmental nerve,intersegmental nerve" FBgn0013670 ms(3)neo79 ms(3)neo79 http://flybase.org/reports/FBgn0013670 - gene - - - ms(3)neo79 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0038202 CG12402 - http://flybase.org/reports/FBgn0038202 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG12402, FBXL11" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR006553:Leucine-rich repeat, cysteine-containing subtype" CG12402 11-Aug-17 DroID_v2017_08 "Drer\zgc:158376, Drer\fbxl6, Drer\lrrc29, Drer\fbxl17, Drer\kdm2aa, Drer\fbxl15, Drer\si:dkey-192l18.9, Drer\kdm2bb, Drer\fbxl4, Drer\kdm2ab" Scer\GRR1 "Cele\B0564.6, Cele\B0564.9" "Xtro\fbxl12, Xtro\kdm2b, Xtro\fbxl19, Xtro\fbxl4" "Mmus\Kdm2b, Mmus\Fbxl4, Mmus\Kdm2a, Mmus\Fbxl19, Mmus\Fbxl17, Mmus\Fbxl21, Mmus\Fbxl6, Mmus\Lrrc29" "Hsap\FBXL19, Hsap\FBXL17, Hsap\FBXL4, Hsap\KDM2A, Hsap\LRRC29, Hsap\FBXL6, Hsap\FBXL13, Hsap\KDM2B" viable FBgn0002352 l(3)87Dd lethal (3) 87Dd http://flybase.org/reports/FBgn0002352 - gene - - - "m14, mes14, l(3)m14, l(3)87Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044025 PK19 Pocket 19 http://flybase.org/reports/FBgn0044025 gene - - - PK19 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010746 l(3)01374 lethal (3) 01374 http://flybase.org/reports/FBgn0010746 - gene - - - "l(3)01373, l(3)01374" - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0024604 olfS20 olfactory S20 http://flybase.org/reports/FBgn0024604 - gene - - - olfS20 - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0000691 flrdO flight reduced O http://flybase.org/reports/FBgn0000691 - gene - - - flrdO - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0004968 juv juvenile http://flybase.org/reports/FBgn0004968 - gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - juv - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal" "dorsal appendage,ovary" FBgn0042125 CG18787 - http://flybase.org/reports/FBgn0042125 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 - - CG18787 "IPR000571:Zinc finger, CCCH-type, IPR025574:Nucleoporin FG repeat" CG18787 11-Aug-17 DroID_v2017_08 Drer\nupl2 - - Xtro\nupl2 Mmus\Nupl2 Hsap\NUPL2 FBgn0031670 CG3887 - http://flybase.org/reports/FBgn0031670 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay CG3887 "IPR011893:Selenoprotein, Rdx type, IPR019389:Selenoprotein T, IPR012336:Thioredoxin-like fold" CG3887 11-Aug-17 DroID_v2017_08 "Drer\selt1b, Drer\selt2, Drer\selt1a" - "Cele\F28H7.4, Cele\C35C5.3" Xtro\selt Mmus\Selenot Hsap\SELENOT FBgn0040032 CG17626 - http://flybase.org/reports/FBgn0040032 protein_coding_gene - - - CG17626 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263907 l(3)GL29 - http://flybase.org/reports/FBgn0263907 gene - - - l(3)GL29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0069200 l(2)DJ690 lethal (2) DJ690 http://flybase.org/reports/FBgn0069200 gene - - - l(2)DJ690 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043905 bns bird's nest soup http://flybase.org/reports/FBgn0043905 gene - meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype - "span, bns, San" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,cytokinesis defective" "contractile ring & meiotic telophase I | male,contractile ring & meiotic telophase II | male" FBgn0031941 ATPsynGL "ATP synthase, subunit G-like" http://flybase.org/reports/FBgn0031941 protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000273103 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000006224" ATP metabolic process ; GO:0046034 | inferred from sequence or structural similarity with RGD:1303259 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000273103 ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000006224 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from biological aspect of ancestor with PANTHER:PTN000273103 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with RGD:1303259" "CG7211, ATPN, ATPsynGL" "IPR006808:ATP synthase, F0 complex, subunit G, mitochondrial, IPR016702:Mitochondrial ATP synthase subunit g, animal" CG7211 11-Aug-17 DroID_v2017_08 Drer\atp5l Scer\ATP20 "Cele\asg-1, Cele\asg-2" Xtro\atp5l Mmus\Atp5l "Hsap\ATP5L, Hsap\ATP5L2" viable FBgn0263047 CG43342 - http://flybase.org/reports/FBgn0263047 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43342, CG12757, CG31169, gpdh-3" IPR004210:BESS motif CG43342 11-Aug-17 DroID_v2017_08 - "Scer\GPD2, Scer\GPD1" "Cele\gpdh-1, Cele\gpdh-2" - Mmus\Gpd1 - FBgn0041340 Circe\pol Circe element pol http://flybase.org/reports/FBgn0041340 transposable_element_gene - - - "ORF2b, ORF2a, Circe\pol" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032030 Wdr82 WD repeat domain 82 http://flybase.org/reports/FBgn0032030 protein_coding_gene chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000458398 histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000458398 histone H3-K4 methylation ; GO:0051568 | inferred from direct assay histone H3-K4 trimethylation ; GO:0080182 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype histone methyltransferase complex ; GO:0035097 | inferred from direct assay Set1C/COMPASS complex ; GO:0048188 | inferred from direct assay "Wdr82, CG17293, wdr-82, dWdr82, wdr82, WDR82" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG17293 11-Aug-17 DroID_v2017_08 "Drer\wdr82, Drer\twf2b, Drer\tlr9, Drer\twf2, Drer\LOC103909995, Drer\twf1b" Scer\SWD2 "Cele\swd-2.2, Cele\swd-2.1" "Xtro\tlr9, Xtro\wdr82, Xtro\twf1, Xtro\twf2" "Mmus\Twf1, Mmus\Wdr82, Mmus\Twf2, Mmus\Tlr9" "Hsap\TWF2, Hsap\TLR9, Hsap\TWF1, Hsap\WDR82" "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,female fertile,fertile" mesothoracic tergum DRSC21723 IEK -3.371119501 -0.852577524 -2.524583738 -3.867727441 0.980847832 1.599820079 FBgn0016632 E(gl)2H Enhancer of glass 2H http://flybase.org/reports/FBgn0016632 - gene - - - E(gl)2H - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017424 CR11538 - http://flybase.org/reports/FBgn0017424 FBgn0036252 non_protein_coding_gene - - - "anon-68Ed, CG11538, CR11538" - CR11538 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002316 l(3)85Ag lethal (3) 85Ag http://flybase.org/reports/FBgn0002316 - gene - - - "L7, l(3)85Ag" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028536 CG15281 - http://flybase.org/reports/FBgn0028536 protein_coding_gene - - - "DS00810.3, BG:DS00810.3, CG18456, BcDNA:RH63170, CG15281" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC02482 K -0.300874438 -0.111137015 -0.217710967 0.289698543 2.397028617 -0.985338632 FBgn0052287 tRNA:Cys-GCA-1-3 transfer RNA:Cysteine-GCA 1-3 http://flybase.org/reports/FBgn0052287 tRNA_gene UGC codon-amino acid adaptor activity ; GO:0033414 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033414 cytosol ; GO:0005829 | inferred by curator from GO:0033414 "CR32287, AE002584.trna16-CysGCA, tRNA:C:GCA:AE002584-e, chr3L.trna16-CysGCA, tRNA:Cys-GCA-1-3, tRNA:CR32287, tRNA-Cys-GCA-1-3, UGC" - CR32287 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265642 lncRNA:TS18 long noncoding RNA: testis-specific 18 http://flybase.org/reports/FBgn0265642 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "lincRNA.267, lncRNA:TS18, CR44449" - CR44449 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010624 l(2)06708 lethal (2) 06708 http://flybase.org/reports/FBgn0010624 - gene - - - l(2)06708 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038973 Pebp1 Phosphatidylethanolamine-binding protein 1 http://flybase.org/reports/FBgn0038973 protein_coding_gene - defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype regulation of antimicrobial humoral response ; GO:0002759 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype - "T2, BcDNA:LP12095, CG18594, Pebp1, PEBP1" IPR008914:Phosphatidylethanolamine-binding protein CG18594 11-Aug-17 DroID_v2017_08 "Drer\mrpl38, Drer\pebp1" "Scer\YLR179C, Scer\MRPL35, Scer\TFS1" "Cele\Y69E1A.5, Cele\F40A3.3" "Xtro\pebp1, Xtro\pebp4, Xtro\mrpl38" "Mmus\Pebp1, Mmus\Mrpl38, Mmus\Pbp2, Mmus\Pebp4" "Hsap\PEBP4, Hsap\PEBP1, Hsap\MRPL38" "immune response defective,viable" FBgn0039797 eIF4H2 eukaryotic translation initiation factor 4H2 http://flybase.org/reports/FBgn0039797 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity RNA strand-exchange activity ; GO:0034057 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity ribosomal small subunit binding ; GO:0043024 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 RNA strand annealing activity ; GO:0033592 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 formation of translation preinitiation complex ; GO:0001731 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 cytoplasmic translation ; GO:0002181 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 translational initiation ; GO:0006413 | inferred from sequence or structural similarity eukaryotic translation initiation factor 4F complex assembly ; GO:0097010 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 cytosol ; GO:0005829 | inferred from sequence or structural similarity polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 "eIF4H, cg1340, CG1340, eIF4H2" IPR000504:RNA recognition motif domain CG1340 11-Aug-17 DroID_v2017_08 "Drer\trnau1apb, Drer\wu:fq32h04, Drer\eif4h, Drer\hnrnpa3, Drer\zcrb1, Drer\ncoa5, Drer\hnrnpc, Drer\hnrnpd, Drer\rbm34, Drer\eif4ba, Drer\hnrnpabb, Drer\dazl, Drer\zgc:55733, Drer\trnau1apa, Drer\cirbpa, Drer\hnrnpaba, Drer\raly, Drer\hnrnpa1b, Drer\srsf10a" "Scer\MUD1, Scer\CWC2, Scer\NOP12, Scer\NAM8, Scer\MRN1, Scer\TIF3, Scer\NOP6, Scer\NGR1, Scer\NAB6" "Cele\H05C05.1, Cele\drr-2" "Xtro\hnrnpab, Xtro\trnau1ap, Xtro\hnrnpd, Xtro\hnrnpc, Xtro\hnrnpa1, Xtro\cirbp, Xtro\eif4h, Xtro\rbm34, Xtro\eif4b, Xtro\dazl, Xtro\hnrnpa2b1, Xtro\hnrnpa3, Xtro\raly, Xtro\hnrnpdl, Xtro\ralyl" "Mmus\Dazl, Mmus\Eif4b, Mmus\Hnrnpa1, Mmus\Zcrb1, Mmus\Tra2b, Mmus\Rbm34, Mmus\Srsf12, Mmus\Boll, Mmus\Hnrnpa3, Mmus\Hnrnpab, Mmus\Eif4h, Mmus\Hnrnpd, Mmus\Slirp, Mmus\Hnrnpa2b1, Mmus\Cirbp, Mmus\Hnrnpc, Mmus\Raly, Mmus\Trnau1ap, Mmus\Rbm31y, Mmus\Gm21379, Mmus\Srsf10" "Hsap\SRSF10, Hsap\RBM3, Hsap\HNRNPAB, Hsap\RALYL, Hsap\HNRNPA1L2, Hsap\DAZ1, Hsap\DAZ4, Hsap\DAZ3, Hsap\HNRNPA2B1, Hsap\RBM34, Hsap\CIRBP, Hsap\DAZL, Hsap\HNRNPC, Hsap\HNRNPA3, Hsap\HNRNPCL1, Hsap\RALY, Hsap\HNRNPA1, Hsap\DAZ2, Hsap\HNRNPD, Hsap\BOLL, Hsap\EIF4H, Hsap\EIF4B, Hsap\SLIRP, Hsap\TRNAU1AP" "visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum FBgn0022387 Mpi Mannose phosphate isomerase http://flybase.org/reports/FBgn0022387 - gene - - - "MPI, Mpi" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036846 MESR6 Misexpression suppressor of ras 6 http://flybase.org/reports/FBgn0036846 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr cellular_component ; GO:0005575 | no biological data available "CG6818, MESR6" IPR024131:Uncharacterised protein family UPF0489 CG6818 11-Aug-17 DroID_v2017_08 Drer\zgc:56556 - "Cele\Y37H2A.7, Cele\ZC196.4, Cele\Y37H2A.18, Cele\fbxa-213" Xtro\c5orf22 Mmus\6030458C11Rik Hsap\C5orf22 "viable,fertile,partially lethal - majority die,wild-type" pupa FBgn0024613 olf345 olfactory 345 http://flybase.org/reports/FBgn0024613 - gene - - - olf345 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065057 scaRNA:MeU2-C28 small Cajal body-specific RNA : MeU2-C28 http://flybase.org/reports/FBgn0065057 snoRNA_gene snRNA 2'-O-ribose methylation guide activity ; GO:0030563 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "Dm-700, snoR700, CR33726, MeU2-C28(SnoR700), snoRNA:700, mgU2-28, scaRNA:MeU2-C28, snoRNA:MeU2-C28" - CR33726 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041746 l(1)em3 lethal (1) em3 http://flybase.org/reports/FBgn0041746 gene - - - l(1)em3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005615 fs(2)lto1 female sterile (2) lto1 http://flybase.org/reports/FBgn0005615 "FBgn0000997, FBgn0004804, FBgn0004810" gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "PN48, fs(2)ltoPN48, fs(2)lo-D, fs(2)PN48, fs(2)lto1" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0035308 CG15822 - http://flybase.org/reports/FBgn0035308 protein_coding_gene - - - CG15822 IPR001251:CRAL-TRIO lipid binding domain CG15822 11-Aug-17 DroID_v2017_08 Drer\sestd1 Scer\CDC24 "Cele\F55D12.2, Cele\uig-1" Xtro\sestd1 "Mmus\D630003M21Rik, Mmus\Sestd1" Hsap\SESTD1 DRSC08482 K 0.118071776 -1.352674248 -0.716369395 -0.272886829 1.706695304 -0.616214263 FBgn0030661 CG8105 - http://flybase.org/reports/FBgn0030661 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 "CG8105, FBgn0030661" "IPR001952:Alkaline phosphatase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG8105 11-Aug-17 DroID_v2017_08 "Drer\alpi.1, Drer\alpl, Drer\alp3, Drer\alpi.2" Scer\PHO8 - "Xtro\alpi.1, Xtro\alpl" "Mmus\Akp3, Mmus\Alppl2, Mmus\Alpl, Mmus\Alpi" "Hsap\ALPP, Hsap\ALPPL2, Hsap\ALPI, Hsap\ALPL" viable FBgn0031119 CG1812 - http://flybase.org/reports/FBgn0031119 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 cell division ; GO:0051301 | inferred from electronic annotation with InterPro:IPR030575 protein ubiquitination ; GO:0016567 | inferred from electronic annotation with InterPro:IPR030575 Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from biological aspect of ancestor with PANTHER:PTN001973695 CG1812 "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR015915:Kelch-type beta propeller, IPR017096:BTB-kelch protein, IPR015916:Galactose oxidase, beta-propeller, IPR030575:Kelch-like protein 22" CG1812 11-Aug-17 DroID_v2017_08 "Drer\klhl14, Drer\klhl30, Drer\klhl36, Drer\klhl31, Drer\si:ch211-63p21.8, Drer\klhl4, Drer\klhdc7a, Drer\klhl42, Drer\klhl22, Drer\klhl13, Drer\si:ch73-29c22.1, Drer\klhl43, Drer\si:ch211-253p14.2, Drer\klhl34, Drer\kbtbd11, Drer\si:dkey-260j18.2, Drer\klhl8, Drer\klhl15, Drer\klhl26, Drer\klhl32, Drer\klhl5, Drer\gan, Drer\LOC101882758, Drer\si:rp71-68n21.9, Drer\kbtbd13" - "Cele\C53A5.6, Cele\C53A5.11, Cele\spe-26, Cele\C53A5.9" "Xtro\klhl14, Xtro\klhl32, Xtro\klhl31, Xtro\klhl13, Xtro\klhl34, Xtro\klhl36, Xtro\kbtbd13, Xtro\klhl22, Xtro\klhl15, Xtro\kbtbd11" "Mmus\Kbtbd13, Mmus\Klhl31, Mmus\Klhl13, Mmus\Klhl5, Mmus\Klhl36, Mmus\Klhl9, Mmus\Klhl8, Mmus\Klhl22, Mmus\Klhl4, Mmus\Klhl26, Mmus\Klhl15, Mmus\Klhl34, Mmus\Klhdc7a, Mmus\Klhl30, Mmus\Klhl14, Mmus\Klhl1, Mmus\Klhl32, Mmus\Klhl42, Mmus\Kbtbd11, Mmus\Klhl33, Mmus\Gan, Mmus\Klhdc7b" "Hsap\KLHL31, Hsap\KLHL1, Hsap\KBTBD13, Hsap\KLHL36, Hsap\KLHL9, Hsap\KLHL26, Hsap\KLHL42, Hsap\KLHL5, Hsap\KLHDC7A, Hsap\KLHL8, Hsap\KBTBD11, Hsap\GAN, Hsap\KLHL32, Hsap\KLHL34, Hsap\KLHL4, Hsap\KLHL22, Hsap\KLHL33, Hsap\KLHL14, Hsap\SCARF2, Hsap\KLHL30, Hsap\KLHDC7B, Hsap\KLHL13, Hsap\KLHL15" viable FBgn0015022 Chap71 Chromosome-associated protein 71kD http://flybase.org/reports/FBgn0015022 - gene chromatin binding ; GO:0003682 | inferred from direct assay - - Chap71 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038570 Prx5 Peroxiredoxin 5 http://flybase.org/reports/FBgn0038570 protein_coding_gene thioredoxin peroxidase activity ; GO:0008379 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cell redox homeostasis ; GO:0045454 | inferred from genetic interaction with Prx3 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype hydrogen peroxide catabolic process ; GO:0042744 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype inferred from genetic interaction with Prx3 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:9355 nucleus ; GO:0005634 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG32920, CG7217, Prx5, dprx5, dPrx5, CG 7217, CG 32920, dPrxV, prx5" "IPR012336:Thioredoxin-like fold, IPR013740:Redoxin, IPR013766:Thioredoxin domain" CG7217 11-Aug-17 DroID_v2017_08 Drer\prdx5 Scer\AHP1 - Xtro\prdx5 Mmus\Prdx5 Hsap\PRDX5 "immune response defective,chemical sensitive,stress response defective,short lived,increased cell death,lethal - all die before end of embryonic stage,parental effect,some die during embryonic stage,long lived,chemical resistant" FBgn0022774 Oat Ornithine aminotransferase precursor http://flybase.org/reports/FBgn0022774 FBgn0036898 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from biological aspect of ancestor with PANTHER:PTN000241033 ornithine-oxo-acid transaminase activity ; GO:0004587 | inferred from sequence or structural similarity with UniProtKB:P04181 identical protein binding ; GO:0042802 | inferred from biological aspect of ancestor with PANTHER:PTN000241033 ornithine-oxo-acid transaminase activity ; GO:0004587 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype ornithine metabolic process ; GO:0006591 | inferred from sequence or structural similarity with UniProtKB:P04181 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P04181 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity mitochondrion ; GO:0005739 | inferred from direct assay "151832_at, CG8782, Oat" "IPR005814:Aminotransferase class-III, IPR010164:Ornithine aminotransferase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR034758:Ornithine aminotransferase, mitochondrial, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG8782 11-Aug-17 DroID_v2017_08 Drer\oat "Scer\BIO3, Scer\CAR2, Scer\ARG8" Cele\oatr-1 Xtro\oat.1 Mmus\Oat Hsap\OAT "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "ganglion mother cell,trichogen cell" FBgn0013565 l(3)78Aa lethal (3) 78Aa http://flybase.org/reports/FBgn0013565 - gene - - - l(3)78Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039052 CG6733 - http://flybase.org/reports/FBgn0039052 protein_coding_gene aminoacylase activity ; GO:0004046 | inferred from electronic annotation with InterPro:IPR010159 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010159 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010159 CG6733 "IPR002933:Peptidase M20, IPR010159:N-acyl-L-amino-acid amidohydrolase, IPR011650:Peptidase M20, dimerisation domain" CG6733 11-Aug-17 DroID_v2017_08 "Drer\LOC100001620, Drer\acy1, Drer\pm20d1.1, Drer\pm20d1.2" Scer\CPS1 "Cele\C10C5.3, Cele\C06A6.4, Cele\C10C5.5, Cele\C10C5.4" "Xtro\pm20d1, Xtro\acy1.1" "Mmus\Pm20d1, Mmus\Acy1" "Hsap\ACY1, Hsap\PM20D1, Hsap\ABHD14A, Hsap\ABHD14A-ACY1" viable FBgn0033309 CG8735 - http://flybase.org/reports/FBgn0033309 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay CG8735 IPR019273:Lunapark domain CG8735 11-Aug-17 DroID_v2017_08 "Drer\lnpa, Drer\lnpb" Scer\LNP1 Cele\lnp-1 Xtro\kiaa1715 Mmus\Lnpk1 Hsap\LNPK "lethal,viable" embryonic/larval brain FBgn0034763 RYBP Ring and YY1 Binding Protein http://flybase.org/reports/FBgn0034763 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 DNA binding ; GO:0003677 | inferred from direct assay programmed cell death involved in cell development ; GO:0010623 | NOT inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype negative regulation of immune response ; GO:0050777 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from genetic interaction with Cul1 inferred from genetic interaction with SkpA inferred from genetic interaction with slmb inferred from physical interaction with Cul1 inferred from physical interaction with SkpA nuclear body ; GO:0016604 | inferred from direct assay "dRYBP, RYBP, CG12190, Rybp" "IPR001876:Zinc finger, RanBP2-type, IPR033774:Yaf2/RYBP C-terminal binding motif" CG12190 11-Aug-17 DroID_v2017_08 "Drer\rybpa, Drer\rybpb, Drer\yaf2" - Cele\tag-294 "Xtro\rybp, Xtro\yaf2" "Mmus\Yaf2, Mmus\Rybp" "Hsap\RYBP, Hsap\YAF2" "partially lethal - majority die,lethal,developmental rate defective,female sterile,visible,somatic clone,increased cell death,size defective,female fertile" "wing vein L5,distal,wing,leg,abdominal sternite 6,male,organism | embryonic stage,somatic clone,trichome & haltere | ectopicsd-SG29.1,wing hair,wing vein,triple row,scutellum,scutum,humerus,ectopic,trichome & haltere | ectopicen-e16E,wing vein L4,trichome of the posterior wing margin,sex comb,metathoracic leg,mesothoracic leg,adult abdominal segment 1,adult abdominal segment 4,wing disc | third instar larval stage,haltere disc | third instar larval stage,ventral thoracic disc | third instar larval stage,antennal disc | third instar larval stage,denticle belt,wing disc,haltere trichome,haltere" FBgn0264990 CG44141 - http://flybase.org/reports/FBgn0264990 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44141 - CG44141 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266851 CR45312 - http://flybase.org/reports/FBgn0266851 non_protein_coding_gene - - - CR45312 - CR45312 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083312 E(smoDN)1411 Enhancer of smoDN 1411 http://flybase.org/reports/FBgn0083312 gene - - - E(smoDN)1411 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037826 CG14689 - http://flybase.org/reports/FBgn0037826 protein_coding_gene phosphatase binding ; GO:0019902 | inferred from electronic annotation with InterPro:IPR026142 negative regulation of phosphatase activity ; GO:0010923 | inferred from electronic annotation with InterPro:IPR026142 - CG14689 IPR026142:Protein phosphatase 1 regulatory subunit 36 CG14689 11-Aug-17 DroID_v2017_08 Drer\ppp1r36 - - - Mmus\Ppp1r36 Hsap\PPP1R36 viable FBgn0065950 l(2)SH0079 lethal (2) SH0079 http://flybase.org/reports/FBgn0065950 gene - - - "l(2)SH0079, l(2)SH2 0079" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038981 CG5346 - http://flybase.org/reports/FBgn0038981 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005123 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 - CG5346 "IPR027443:Isopenicillin N synthase-like, IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR026992:Non-haem dioxygenase N-terminal domain" CG5346 11-Aug-17 DroID_v2017_08 Drer\si:dkey-10o6.2 - - - - - viable DRSC15778 E -0.341765182 -0.639149619 3.528378989 0.633052156 0.640747805 0.118389453 FBgn0036733 U4-U6-60K U4-U6 small nuclear riboprotein factor 60K http://flybase.org/reports/FBgn0036733 protein_coding_gene U6 snRNA binding ; GO:0017070 | inferred from direct assay U4 snRNA binding ; GO:0030621 | inferred from direct assay "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000457233 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000006382" U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000457233 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000006382 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "U4-U6-60K, U4/U6-60K, CG6322, Prp4" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR014906:Pre-mRNA processing factor 4 (PRP4)-like, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG6322 11-Aug-17 DroID_v2017_08 "Drer\prpf4, Drer\daw1" Scer\PRP4 Cele\prp-4 "Xtro\prpf4, Xtro\daw1" "Mmus\Prpf4, Mmus\Daw1" "Hsap\PRPF4, Hsap\DAW1" lethal FBgn0041255 E3 E3 http://flybase.org/reports/FBgn0041255 gene - - - E3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043873 nertoo nertoo http://flybase.org/reports/FBgn0043873 gene - - - nertoo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267376 SelR Selenoprotein R http://flybase.org/reports/FBgn0267376 protein_coding_gene peptide-methionine (R)-S-oxide reductase activity ; GO:0033743 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence or structural similarity inferred from direct assay peptide-methionine (R)-S-oxide reductase activity ; GO:0033743 | inferred from sequence or structural similarity inferred from direct assay methionine-R-sulfoxide reductase activity ; GO:0070191 | inferred from direct assay oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002579 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR028427 protein repair ; GO:0030091 | inferred from electronic annotation with InterPro:IPR028427 actin filament organization ; GO:0007015 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype actin filament polymerization ; GO:0030041 | inferred from genetic interaction with Mical axon guidance ; GO:0007411 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CG6584, SelR, MsrB, EP3340, BcDNA:RH61230, BcDNA:RE36040, selR, dMsrB" "IPR028427:Peptide methionine sulfoxide reductase, IPR002579:Peptide methionine sulphoxide reductase MrsB, IPR011057:Mss4-like" CG6584 11-Aug-17 DroID_v2017_08 "Drer\msrb3, Drer\smc6, Drer\msrb1b, Drer\msrb2, Drer\si:dkey-119f1.1, Drer\msrb1a" Scer\MXR2 "Cele\F44E2.6, Cele\C23H4.6, Cele\smc-6" "Xtro\smc6, Xtro\msrb2" "Mmus\Msrb1, Mmus\Msrb2, Mmus\Msrb3" "Hsap\MSRB1, Hsap\MSRB3, Hsap\SMC6, Hsap\MSRB2" neuroanatomy defective "intersegmental nerve,macrochaeta,embryonic/larval somatic muscle | third instar larval stage,filamentous actin | third instar larval stagehow-24B,filamentous actin | third instar larval stageMef2.PR,intersegmental nerve branch ISNb of A1-7,synapseelav.PU" FBgn0000104 aperC abnormal proboscis extension reflex C http://flybase.org/reports/FBgn0000104 - gene - muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype proboscis extension reflex ; GO:0007637 | inferred from mutant phenotype - aperC - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,recessive,cold sensitive,behavior defective,heat sensitive" "proboscis muscle 1,cold sensitive" FBgn0036767 CG16775 - http://flybase.org/reports/FBgn0036767 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG16775 "IPR024518:Domain of unknown function DUF3421, IPR006616:DM9 repeat" CG16775 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011597 grap88D grapes at 88D http://flybase.org/reports/FBgn0011597 - gene - - - "grap88D, grap" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile nurse cell FBgn0022384 Nbp70 Nuclear localization sequence-binding protein 70 http://flybase.org/reports/FBgn0022384 - gene nuclear localization sequence binding ; GO:0008139 | inferred from sequence or structural similarity protein import into nucleus ; GO:0006606 | traceable author statement cytosol ; GO:0005829 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from sequence or structural similarity "NBP70, Nbp70" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070015 BG01128 BG01128 http://flybase.org/reports/FBgn0070015 gene - - - BG01128 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0031540 Pif1 Pif1 ortholog http://flybase.org/reports/FBgn0031540 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003840 telomerase inhibitor activity ; GO:0010521 | inferred from biological aspect of ancestor with PANTHER:PTN001512181 ATP-dependent 5'-3' DNA helicase activity ; GO:0043141 | inferred from biological aspect of ancestor with PANTHER:PTN001149889 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR010285 DNA duplex unwinding ; GO:0032508 | inferred from biological aspect of ancestor with PANTHER:PTN001149889 negative regulation of telomerase activity ; GO:0051974 | inferred from biological aspect of ancestor with PANTHER:PTN001512181 negative regulation of telomere maintenance via telomerase ; GO:0032211 | inferred from biological aspect of ancestor with PANTHER:PTN001512181 DNA replication ; GO:0006260 | inferred from biological aspect of ancestor with PANTHER:PTN001149889 mitochondrial genome maintenance ; GO:0000002 | inferred from biological aspect of ancestor with PANTHER:PTN001512181 G-quadruplex DNA unwinding ; GO:0044806 | inferred from biological aspect of ancestor with PANTHER:PTN001512181 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001512181 replication fork ; GO:0005657 | inferred from biological aspect of ancestor with PANTHER:PTN001149889 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001512181 "CG3238, Pif1, pif1" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR010285:DNA helicase Pif1-like, IPR003840:DNA helicase" CG3238 11-Aug-17 DroID_v2017_08 Drer\pif1 "Scer\RRM3, Scer\PIF1" "Cele\Y46B2A.2, Cele\pif-1, Cele\C11G6.2, Cele\Y116F11A.1, Cele\F59H6.5, Cele\F33H12.6" "Xtro\LOC101730335, Xtro\pif1" Mmus\Pif1 Hsap\PIF1 "viable,fertile" FBgn0036681 Obp73a Odorant-binding protein 73a http://flybase.org/reports/FBgn0036681 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "Obp73a, CG13027, DmelObp73a" IPR006170:Pheromone/general odorant binding protein CG13027 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033979 Cyp6a19 Cyp6a19 http://flybase.org/reports/FBgn0033979 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR002402 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR002402 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002402 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR002402, InterPro:IPR017972" - "6a19, CG10243, Cyp6a19" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site, IPR002402:Cytochrome P450, E-class, group II" CG10243 11-Aug-17 DroID_v2017_08 "Drer\cyp3c2, Drer\tbxas1, Drer\cyp3a65, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp3c4, Drer\cyp4t8, Drer\cyp4f3" Scer\ERG11 "Cele\cyp-44A1, Cele\cyp-32A1, Cele\cyp-25A2, Cele\cyp-25A1, Cele\cyp-25A6, Cele\cyp-13A11, Cele\cyp-13A8, Cele\cyp-43A1, Cele\cyp-29A4, Cele\cyp-25A3, Cele\cyp-29A3, Cele\cyp-13A5, Cele\cyp-25A4, Cele\cyp-29A2, Cele\cyp-31A2, Cele\cyp-13A2, Cele\cyp-37B1, Cele\cyp-13B2, Cele\cyp-31A3, Cele\cyp-13B1, Cele\cyp-32B1, Cele\cyp-13A12, Cele\cyp-13A10, Cele\cyp-13A3, Cele\cyp-13A1, Cele\cyp-13A6, Cele\cyp-13A4, Cele\cyp-13A7, Cele\cyp-42A1" "Xtro\cyp3a5, Xtro\tbxas1, Xtro\cyp3a4, Xtro\LOC100494419" "Mmus\Cyp3a11, Mmus\Cyp4f15, Mmus\Cyp4a32, Mmus\Cyp4f18, Mmus\Cyp4f16, Mmus\Cyp4f37, Mmus\Cyp4a31, Mmus\Tbxas1, Mmus\Cyp3a41a, Mmus\Cyp3a57, Mmus\Cyp4a10, Mmus\Cyp4v3, Mmus\Cyp4a14, Mmus\Cyp4a12b, Mmus\Cyp3a25, Mmus\Cyp3a41b, Mmus\Cyp2c66, Mmus\Cyp3a44, Mmus\Cyp4f39, Mmus\Cyp4a12a, Mmus\Cyp3a16, Mmus\Cyp4f14, Mmus\Cyp4f13, Mmus\Cyp3a59, Mmus\Cyp3a13, Mmus\Cyp4b1" "Hsap\CYP4F11, Hsap\CYP4A22, Hsap\CYP4F3, Hsap\CYP3A43, Hsap\CYP3A5, Hsap\CYP4Z1, Hsap\CYP4B1, Hsap\TBXAS1, Hsap\CYP4F8, Hsap\CYP3A4, Hsap\CYP4F2, Hsap\CYP2C18, Hsap\CYP4F12, Hsap\CYP3A7, Hsap\CYP4A11, Hsap\CYP4V2, Hsap\CYP2C8, Hsap\CYP4F22, Hsap\CYP4X1, Hsap\CYP3A7-CYP3A51P" viable FBgn0267964 CG46244 - http://flybase.org/reports/FBgn0267964 protein_coding_gene - - - "CG46244, Dm_2L:103252" - CG46244 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263705 Myo10A Myosin 10A http://flybase.org/reports/FBgn0263705 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609 motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609 protein binding ; GO:0005515 | inferred from physical interaction with Hsp26 inferred from physical interaction with crp inferred from physical interaction with shg inferred from physical interaction with αTub84D inferred from physical interaction with RpL23 inferred from physical interaction with smg inferred from physical interaction with Cpsf160 inferred from physical interaction with inc inferred from physical interaction with Bap60 inferred from physical interaction with Eb1 inferred from physical interaction with Kap-α3 inferred from physical interaction with CG2258 inferred from physical interaction with CG5613 inferred from physical interaction with Socs16D inferred from physical interaction with CG2765 inferred from physical interaction with CG18135 inferred from physical interaction with Fip1 inferred from physical interaction with CG6834 inferred from physical interaction with RpL34a inferred from physical interaction with Kat60 inferred from physical interaction with Nedd4 inferred from physical interaction with aPKC inferred from physical interaction with milt inferred from physical interaction with tgo inferred from physical interaction with elgi ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" intracellular protein transport ; GO:0006886 | inferred from mutant phenotype filopodium assembly ; GO:0046847 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609 neuronal cell body ; GO:0043025 | inferred from direct assay myosin complex ; GO:0016459 | inferred from sequence or structural similarity filopodium ; GO:0030175 | inferred from direct assay "CG43657, Myo10A, 10A, DmXV, AAF47980, CG2174, CG2136, Syph, CG16922, myo10A, Myo20" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001609:Myosin head, motor domain, IPR019748:FERM central domain, IPR011993:PH domain-like, IPR000857:MyTH4 domain, IPR000048:IQ motif, EF-hand binding site, IPR019749:Band 4.1 domain, IPR000299:FERM domain" CG43657 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-194h10.2, Drer\myo10l3, Drer\myo7ab, Drer\myo9b, Drer\myo15b, Drer\myo9ab, Drer\si:dkeyp-92c9.3, Drer\si:ch211-94l19.4, Drer\myo3b, Drer\myo10, Drer\LOC556989, Drer\myo9aa, Drer\myo7bb, Drer\myo15ab, Drer\myo10l1, Drer\myo7aa, Drer\myo15aa" "Scer\MYO5, Scer\MYO2, Scer\MYO3" "Cele\hum-5, Cele\hum-6, Cele\hum-4" "Xtro\myo9a, Xtro\myo3b, Xtro\myo3a, Xtro\myo10.2, Xtro\myo7a, Xtro\myo10" "Mmus\Myo10, Mmus\Myo1d, Mmus\Myo1g, Mmus\Myo7b, Mmus\Myo15, Mmus\Myo7a, Mmus\Myo9b, Mmus\Myo3b, Mmus\Myo3a, Mmus\Myo9a" "Hsap\MYO3A, Hsap\MYO1D, Hsap\MYO3B, Hsap\MYO10, Hsap\MYO1G, Hsap\MYO9A, Hsap\MYO7B, Hsap\MYO15B, Hsap\MYO7A, Hsap\MYO15A, Hsap\MYO9B" FBgn0058117 CG40117 - http://flybase.org/reports/FBgn0058117 protein_coding_gene - - - CG40117 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044003 Su(rst)C233 Su(rst)C233 http://flybase.org/reports/FBgn0044003 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C233, Su(rst)C233" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266858 CR45319 - http://flybase.org/reports/FBgn0266858 non_protein_coding_gene - - - CR45319 - CR45319 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005515 l(1)DC371 lethal (1) DC371 http://flybase.org/reports/FBgn0005515 - gene - - - l(1)DC371 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male fertile,heat sensitive" FBgn0004777 Ccp84Ag Ccp84Ag http://flybase.org/reports/FBgn0004777 FBgn0063076 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "cc2, CG2342, BG:DS00004.7, BcDNA:RE04513, Ccp84Ag, Ccp, DmelCcp84Ag" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2342 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "viable,visible" mesothoracic tergum FBgn0050053 CG30053 - http://flybase.org/reports/FBgn0050053 protein_coding_gene - - - "CG8769, CG30053" - CG30053 11-Aug-17 DroID_v2017_08 - - Cele\psr-1 - - - viable FBgn0044398 Scim29 Sensitized chromosome inheritance modifier 29 http://flybase.org/reports/FBgn0044398 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0025171 l(2)38De lethal (2) 38De http://flybase.org/reports/FBgn0025171 - gene - - - l(2)38De - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260353 GSd112 - http://flybase.org/reports/FBgn0260353 gene - - - GSd112 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0041632 F-element\gag-r F element gag-related http://flybase.org/reports/FBgn0041632 transposable_element_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - "F-ORF1, F\ORF1, F-element\gag-r" "IPR001878:Zinc finger, CCHC-type, IPR006579:Pre-C2HC domain" - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , adult stage && oogenesis stage , embryonic stage | blastoderm " " embryonic/larval muscle system

, follicle cell

, embryonic central nervous system

, embryonic/larval salivary gland

,

posterior , embryonic/larval tracheal system

, testis

, embryonic/larval foregut

, nurse cell

, amnioserosa

" FBgn0005508 l(2)24EFf lethal (2) 24EFf http://flybase.org/reports/FBgn0005508 - gene - - - "l(2)Gr.VI, l(2)24EFf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266165 CR44871 - http://flybase.org/reports/FBgn0266165 non_protein_coding_gene - - - CR44871 - CR44871 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266810 CR45272 - http://flybase.org/reports/FBgn0266810 non_protein_coding_gene - - - CR45272 - CR45272 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004070 fs(2)mel4 female sterile (2) maternal effect lethal 4 http://flybase.org/reports/FBgn0004070 - gene - - - "mel 4, fs(2)mel4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "cephalopharyngeal skeleton,maternal effect,mouth hooks,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,metathoracic ventral denticle belt,mesothoracic ventral denticle belt,prothoracic ventral denticle belt,stomodeum" FBgn0010676 l(2)rK639 lethal (2) rK639 http://flybase.net/reports/FBgn0010676.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" "crystal cell,mitotic cell cycle" FBgn0001670 l(1)EN6 lethal (1) from Eugene Nonautonomous 6 http://flybase.org/reports/FBgn0001670 - gene - - - l(1)EN6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval fat body,Malpighian tubule" FBgn0051498 CG31498 - http://flybase.org/reports/FBgn0051498 protein_coding_gene - - - CG31498 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267296 CR45732 - http://flybase.org/reports/FBgn0267296 non_protein_coding_gene - - - CR45732 - CR45732 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267652 pre-mod(mdg4)-N - http://flybase.org/reports/FBgn0267652 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-N, CG45990" "IPR007588:Zinc finger, FLYWCH-type" CG45990 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084184 W184 W184 http://flybase.org/reports/FBgn0084184 gene - - - W184 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0024574 l(3)rH304 lethal (3) rH304 http://flybase.org/reports/FBgn0024574 - gene - - - l(3)rH304 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085485 CG34456 - http://flybase.org/reports/FBgn0085485 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:O00764 "CG34456, CG4446" - CG34456 11-Aug-17 DroID_v2017_08 "Drer\pdxkb, Drer\pdxka" "Scer\BUD17, Scer\BUD16" - Xtro\pdxk Mmus\Pdxk Hsap\PDXK FBgn0083076 ms(2)kn66 ms(2)kn66 http://flybase.org/reports/FBgn0083076 gene - - - ms(2)kn66 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002059 l(2)40Fd lethal (2) 40Fd http://flybase.org/reports/FBgn0002059 - gene - - - "40Fd, l(2Lh)Fd, GroupVIII, l(2)40Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" "wing,femur" FBgn0069121 ms(3)Z2420 ms(3)Z2420 http://flybase.org/reports/FBgn0069121 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(3)Z2420 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile spermatid FBgn0264906 CR44097 - http://flybase.org/reports/FBgn0264906 non_protein_coding_gene - - - CR44097 - CR44097 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085352 CG34323 - http://flybase.org/reports/FBgn0085352 protein_coding_gene - - - CG34323 "IPR008984:SMAD/FHA domain, IPR000253:Forkhead-associated (FHA) domain" CG34323 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014322 l(3)ry15 lethal (3) ry15 http://flybase.org/reports/FBgn0014322 - gene - - - l(3)ry15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260251 GSd325 - http://flybase.org/reports/FBgn0260251 gene - - - GSd325 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "intersegmental nerve,segmental nerve,embryonic somatic muscle,ventral nerve cord" FBgn0022368 Pt-5 Larval protein-5 http://flybase.org/reports/FBgn0022368 - gene - - - Pt-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004935 Altered-abdomen Altered abdomen http://flybase.org/reports/FBgn0004935 - gene - - - "Altered-abdomen, Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" tergite FBgn0267625 CR45963 - http://flybase.org/reports/FBgn0267625 non_protein_coding_gene - - - CR45963 - CR45963 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030680 CG8944 - http://flybase.org/reports/FBgn0030680 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG8944 "IPR006578:MADF domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG8944 11-Aug-17 DroID_v2017_08 "Drer\zgc:66443, Drer\si:ch73-138e16.4, Drer\si:ch211-113e8.10" "Scer\STP4, Scer\STP3" - - "Mmus\Zfp91, Mmus\Zfp980, Mmus\Zfp995, Mmus\Gm13212" "Hsap\ZFP91, Hsap\ZNF585A, Hsap\ZNF711, Hsap\ZNF85" "viable,visible" mesothoracic tergum DRSC21342 K -0.571161174 0.533526205 -0.187333621 0.523137273 -0.507376374 1.525100589 FBgn0065656 l(2)SH0721 lethal (2) SH0721 http://flybase.org/reports/FBgn0065656 gene - - - "l(2)SH0721, l(2)SH2 0721" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002906 Blm Bloom syndrome helicase http://flybase.org/reports/FBgn0002906 FBgn0015800 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent DNA helicase activity ; GO:0004003 | inferred from sequence or structural similarity with HGNC:1058 Y-form DNA binding ; GO:0000403 | inferred from direct assay ATP-dependent 3'-5' DNA helicase activity ; GO:0043140 | inferred from direct assay four-way junction helicase activity ; GO:0009378 | inferred from biological aspect of ancestor with PANTHER:PTN000344873 DNA helicase activity ; GO:0003678 | inferred from sequence or structural similarity with HGNC:1058 DNA-dependent ATPase activity ; GO:0008094 | inferred from direct assay" DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR018982 double-strand break repair via synthesis-dependent strand annealing ; GO:0045003 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from genetic interaction with SGD:S000004802 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype double-strand break repair via nonhomologous end joining ; GO:0006303 | inferred from genetic interaction with Irbp inferred from genetic interaction with Ku80 DNA strand renaturation ; GO:0000733 | inferred from direct assay DNA repair ; GO:0006281 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype strand displacement ; GO:0000732 | inferred from direct assay double-strand break repair ; GO:0006302 | inferred from mutant phenotype negative regulation of double-strand break repair via single-strand annealing ; GO:1901291 | inferred from mutant phenotype DNA synthesis involved in DNA repair ; GO:0000731 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from genetic interaction with Gen DNA duplex unwinding ; GO:0032508 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000344873 nucleus ; GO:0005634 | inferred from direct assay chromosome ; GO:0005694 | inferred from biological aspect of ancestor with PANTHER:PTN000344873 "DmBlm, DmBLM, mus 309, Dmblm, blm, DmKu70, RecQ, CG6920, Blm, MUS309, mus309, ku70, Ku70, dBLM, BLM, dmblm, Mus309" "IPR001650:Helicase, C-terminal, IPR002121:HRDC domain, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR004589:DNA helicase, ATP-dependent, RecQ type, IPR011545:DEAD/DEAH box helicase domain, IPR010997:HRDC-like, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR018982:RQC domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR032284:ATP-dependent DNA helicase RecQ, zinc-binding domain" CG6920 11-Aug-17 DroID_v2017_08 "Drer\blm, Drer\recql, Drer\recql5, Drer\recql4, Drer\wrn" Scer\SGS1 "Cele\wrn-1, Cele\K02F3.12, Cele\him-6, Cele\rcq-5" "Xtro\recql, Xtro\blm, Xtro\recql4, Xtro\wrn" "Mmus\Recql5, Mmus\Blm, Mmus\Wrn, Mmus\Recql4, Mmus\Recql" "Hsap\BLM, Hsap\RECQL5, Hsap\WRN, Hsap\RECQL" embryonic stage -- adult stage "radiation sensitive,recessive,increased cell death,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,chemical sensitive,female sterile,male sterile,partially,DNA repair defective,semidominant,dominant,viable,wild-type,fertile" "wing disc,syncytial blastoderm embryo,maternal effect" FBgn0020882 alan alae angustae http://flybase.org/reports/FBgn0020882 - gene - - - alan - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0262461 mir-315 mir-315 stem loop http://flybase.org/reports/FBgn0262461 miRNA_gene - positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from direct assay negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype - "dme-mir-315, miR-315, mir-315, MIR-315, CR43036, CR33619, pre-mir-315" - CR43036 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,lethal - all die before end of P-stage,some die during P-stage" "eye,wing,wing pouch,ectopic" FBgn0003065 CG2150 - http://flybase.org/reports/FBgn0003065 - protein_coding_gene - - - "GCR 1, GCR1, pen100DE, anon-Pen100DE, Pen100DE, CG2150, GCR-1" - CG2150 11-Aug-17 DroID_v2017_08 - - "Cele\nlp-27, Cele\nlp-31, Cele\fipr-9, Cele\nlp-28, Cele\nlp-30, Cele\fipr-6, Cele\fipr-1, Cele\nlp-29, Cele\fipr-5, Cele\fipr-4, Cele\Y43C5A.3, Cele\fipr-10, Cele\fipr-12, Cele\R13D11.10, Cele\fipr-11, Cele\fipr-3, Cele\fipr-7, Cele\fipr-8" - - - "viable,body color defective" mesothoracic tergum FBgn0267946 CR46226 - http://flybase.org/reports/FBgn0267946 non_protein_coding_gene - - - "CR46226, lincRNA.720" - CR46226 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023438 hl halteroptera http://flybase.org/reports/FBgn0023438 - gene - - - hl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "haltere,metathoracic segment" FBgn0250827 whip whipple http://flybase.org/reports/FBgn0250827 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs34h06, NEST:bs36g01, whip, CG34218, CG2149" - CG34218 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267224 CR45664 - http://flybase.org/reports/FBgn0267224 non_protein_coding_gene - - - CR45664 - CR45664 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034281 CG14490 - http://flybase.org/reports/FBgn0034281 protein_coding_gene - - - CG14490 IPR003409:MORN motif CG14490 11-Aug-17 DroID_v2017_08 "Drer\jph1a, Drer\si:ch211-146m13.3, Drer\als2b, Drer\morn3, Drer\jph1b, Drer\rsph1, Drer\rsph10b, Drer\als2a, Drer\jph2, Drer\morn4, Drer\jph3" - - "Xtro\rsph1, Xtro\jph1, Xtro\als2cl, Xtro\morn5, Xtro\jph2, Xtro\morn3, Xtro\rsph10b, Xtro\als2" "Mmus\Jph1, Mmus\Morn1, Mmus\Jph2, Mmus\Morn4, Mmus\Rsph1, Mmus\Jph4, Mmus\Morn3, Mmus\Jph3, Mmus\Als2cl, Mmus\Morn5, Mmus\Als2" "Hsap\MORN3, Hsap\RSPH10B, Hsap\MORN4, Hsap\ALS2CL, Hsap\JPH1, Hsap\MORN1, Hsap\RSPH10B2, Hsap\MORN5, Hsap\ALS2, Hsap\JPH2, Hsap\JPH4, Hsap\JPH3, Hsap\RSPH1" viable FBgn0063449 Uhg2 U snoRNA host gene 2 http://flybase.org/reports/FBgn0063449 non_protein_coding_gene - - - "Dros-UHG2, dUHG2, CR32873, Uhg2, dUhg2" - CR32873 11-Aug-17 DroID_v2017_08 - - - - - - DRSC01100 E -1.356605913 -0.770445335 3.104442768 0.746955651 0.347129281 0.196847117 FBgn0052729 CG32729 - http://flybase.org/reports/FBgn0052729 protein_coding_gene - - - CG32729 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003094 pkh pinkish http://flybase.org/reports/FBgn0003094 - gene - - - pkh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069136 mcl(3)Z6256 mcl(3)Z6256 http://flybase.org/reports/FBgn0069136 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z6256 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0086039 snoRNA:Me28S-A2113 - http://flybase.org/reports/FBgn0086039 snoRNA_gene - - - "28S-Am2113, Me28S-A2113, CR34668, snoRNA:Me28S-A2113, snoRNA:28S-A2113" - CR34668 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000606 eve even skipped http://flybase.org/reports/FBgn0000606 "FBgn0014159, FBgn0014984, FBgn0015483, FBgn0017400, FBgn0019712, FBgn0019718, FBgn0019720, FBgn0019721, FBgn0019816, FBgn0023205" protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "muscle organ development ; GO:0007517 | traceable author statement trunk segmentation ; GO:0035290 | traceable author statement regulation of axonogenesis ; GO:0050770 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from expression pattern negative regulation of cardioblast cell fate specification ; GO:0009997 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | non-traceable author statement regulation of myoblast fusion ; GO:1901739 | inferred from mutant phenotype germ-band extension ; GO:0007377 | traceable author statement heart development ; GO:0007507 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay heart morphogenesis ; GO:0003007 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype periodic partitioning by pair rule gene ; GO:0007366 | traceable author statement germ-band extension ; GO:0007377 | inferred from mutant phenotype periodic partitioning by pair rule gene ; GO:0007366 | non-traceable author statement central nervous system development ; GO:0007417 | non-traceable author statement adult heart development ; GO:0007512 | inferred from mutant phenotype cell fate determination ; GO:0001709 | non-traceable author statement posterior head segmentation ; GO:0035289 | traceable author statement cephalic furrow formation ; GO:0007376 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "eve, Eve, eve2, CG2328, E(eve), EVE, F, l(2)46Ce, VI, V, 10.5, 14.10, 10.9, 20.35, l(2)46CFp, l(2)46CFj, l(2)46CFh, l(2)46CFg, l(2)46Cg, even, dm-eve" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG2328 11-Aug-17 DroID_v2017_08 "Drer\eve1, Drer\evx2, Drer\evx1" - "Cele\vab-7, Cele\ceh-30, Cele\ceh-31" "Xtro\evx2, Xtro\evx1" "Mmus\Evx1, Mmus\Evx2, Mmus\Alx3" "Hsap\EVX1, Hsap\EVX2" " embryonic stage | stage 4-12 , embryonic stage | stage 1-15 , larval stage , embryonic stage | stage 1-17 , embryonic stage | stage 3 , embryonic stage | stage >12 " " parasegment 1,3,5,7,9,11,13

,

20-70% egg length , parasegment 1--14

, ganglion mother cell | segmentally repeated

" " embryonic stage | stage 13 , embryonic stage | stage 8-12 , embryonic stage | blastoderm , embryonic stage | stage 4-5 , embryonic stage | stage >12 , embryonic stage | stage 12 , embryonic stage , embryonic stage | stage 3-11 " " embryonic pericardial cell | subset

, parasegment 1--14

,

pair rule , organism | pair rule

, neurogenic region

, abdominal dorsal acute muscle 1

, proctodeum | presumptive

, cardioblast

, parasegment 1,3,5,7,9,11,13

" "lethal,recessive,developmental rate defective,viable,heat sensitive,pair rule phenotype,wild-type,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell death,cell polarity defective,somatic clone,partially lethal - majority die,some die during pupal stage" "parasegment 4,parasegment 5,parasegment 6,extended germ band embryo,embryonic segment,embryonic/first instar larval cuticle,parasegment 3,embryo,cuticle,parasegment,,adult heart,abdominal segment,RP2 motor neuron,aCC neuron,pCC neuron,embryonic mesothoracic segment,eve5,pericardial cell,abdominal dorsal acute muscle,presumptive embryonic/larval nervous system,embryonic/larval visceral muscle,embryonic/larval somatic muscle,cephalic furrow,intersegmental nerve,mitotic domain 2,embryonic/larval fat body,parasegment 1,eve1,ectoderm,U neuron,abdominal intersegmental nerve,mesothoracic intersegmental nerve,metathoracic intersegmental nerve,prothoracic intersegmental nerve,VUM neuron,presumptive embryonic/larval central nervous system,germ band,cardioblast,heart primordium,cardiac outflow muscle,embryonic/larval heart anchoring cell,embryonic heart anchoring cell primordium,ftz.ng,adult hindgut primordium,dMP2 neuron,dorsal transverse muscle,ventral acute muscle 2,nucleus" FBgn0039463 CG18472 - http://flybase.org/reports/FBgn0039463 protein_coding_gene heat shock protein binding ; GO:0031072 | inferred from sequence or structural similarity with HGNC:15746 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with HGNC:15746 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with HGNC:15746 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:15746 CG18472 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG18472 11-Aug-17 DroID_v2017_08 "Drer\tomm34, Drer\ifit8, Drer\ifit9, Drer\dyx1c1, Drer\kdm6a, Drer\ttc6, Drer\aip, Drer\ttc12, Drer\bbs4, Drer\tomm70a, Drer\ifit14, Drer\ttc4, Drer\ttc25, Drer\spag1b, Drer\ccdc178, Drer\spag1a, Drer\tmtc3, Drer\kdm6al, Drer\kdm6ba, Drer\tex11, Drer\zgc:123010, Drer\ogt.1, Drer\fkbpl, Drer\si:dkey-33c12.4, Drer\ifit16, Drer\ogt.2, Drer\ifit15" "Scer\TAH1, Scer\CNS1, Scer\SWA2, Scer\TOM71, Scer\TOM70, Scer\CYC8, Scer\STI1" "Cele\C56C10.10, Cele\C33H5.8" "Xtro\kdm6a, Xtro\bbs4, Xtro\tomm70a, Xtro\ttc16, Xtro\kdm6b, Xtro\aip, Xtro\ogt, Xtro\spag1, Xtro\ttc25, Xtro\dyx1c1, Xtro\ifit5, Xtro\tmtc3" "Mmus\Ifit2, Mmus\Tomm34, Mmus\Ifit1bl1, Mmus\Ifit1bl2, Mmus\Tex11, Mmus\Bbs4, Mmus\Kdm6b, Mmus\Aip, Mmus\Ttc4, Mmus\Uty, Mmus\Ifit1, Mmus\Ttc16, Mmus\Fkbpl, Mmus\Ttc24, Mmus\Kdm6a, Mmus\Spag1, Mmus\Tomm70a, Mmus\Ogt, Mmus\Tmtc3, Mmus\Ifit3, Mmus\Ifit3b, Mmus\Lonrf3, Mmus\Ttc25, Mmus\Dyx1c1, Mmus\Tmtc1" "Hsap\TEX11, Hsap\TTC32, Hsap\TTC31, Hsap\UTY, Hsap\AIP, Hsap\KDM6A, Hsap\BBS4, Hsap\KDM6B, Hsap\IFIT5, Hsap\TMTC1, Hsap\IFIT1B, Hsap\LONRF2, Hsap\TOMM70, Hsap\TTC6, Hsap\TTC16, Hsap\OGT, Hsap\FKBPL, Hsap\TMTC3, Hsap\DYX1C1, Hsap\LONRF3, Hsap\TTC24, Hsap\TOMM34, Hsap\IFIT2, Hsap\IFIT3, Hsap\SPAG1, Hsap\TTC4, Hsap\IFIT1" viable FBgn0259570 B2023 - http://flybase.org/reports/FBgn0259570 gene - - - B2023 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,tarsal segment" FBgn0001892 l(2)21Df lethal (2) 21Df http://flybase.org/reports/FBgn0001892 - gene - - - "l(2)neh-6, l(2)neh6, l(2)21Df" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016920 nompC no mechanoreceptor potential C http://flybase.org/reports/FBgn0016920 "FBgn0001928, FBgn0031704, FBgn0031705" protein_coding_gene calcium channel activity ; GO:0005262 | inferred from electronic annotation with InterPro:IPR002153 ion channel activity ; GO:0005216 | inferred from sequence or structural similarity mechanically-gated ion channel activity ; GO:0008381 | traceable author statement ankyrin binding ; GO:0030506 | non-traceable author statement cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity mechanically-gated ion channel activity ; GO:0008381 | non-traceable author statement cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with pyx calcium ion transmembrane transport ; GO:0070588 | inferred from electronic annotation with InterPro:IPR002153 response to auditory stimulus ; GO:0010996 | inferred from direct assay detection of mechanical stimulus involved in sensory perception of touch ; GO:0050976 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity cellular response to mechanical stimulus ; GO:0071260 | inferred from mutant phenotype sensory perception of mechanical stimulus ; GO:0050954 | inferred from mutant phenotype sensory perception of mechanical stimulus ; GO:0050954 | non-traceable author statement startle response ; GO:0001964 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from sequence or structural similarity with pyx sensory perception of touch ; GO:0050975 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception ; GO:0050974 | traceable author statement locomotion ; GO:0040011 | inferred from mutant phenotype mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype dendrite ; GO:0030425 | inferred from direct assay spanning component of plasma membrane ; GO:0044214 | inferred from direct assay cilium ; GO:0005929 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with pyx "CG11020, NOMPC, CT30855, l(2)jf24, jf24, nomp, l(2)25Dc, CG17468, nompC, NompC, TRPN, ORE-13, TRPN1, DmNompC" "IPR002110:Ankyrin repeat, IPR005821:Ion transport domain, IPR020683:Ankyrin repeat-containing domain, IPR002153:Transient receptor potential channel, canonical" CG11020 11-Aug-17 DroID_v2017_08 "Drer\trpc6a, Drer\ankef1b, Drer\trpc3, Drer\ankdd1a, Drer\tnksa, Drer\si:dkey-86e18.2, Drer\invs, Drer\tnksb, Drer\ank1a, Drer\ankk1, Drer\trpc2b, Drer\ankrd27, Drer\ankdd1b, Drer\trpc2a, Drer\psmd10, Drer\si:ch73-193i2.2, Drer\ankef1a, Drer\trpc4a, Drer\trpc1, Drer\ank2a, Drer\zgc:110224, Drer\ank3b, Drer\hace1, Drer\pidd1, Drer\si:ch211-203b8.6, Drer\trpn1, Drer\ank3a, Drer\trpc7a, Drer\ank1b" Scer\NAS6 "Cele\F40G9.17, Cele\trp-4" "Xtro\trpc4, Xtro\tnks2, Xtro\hace1, Xtro\trpc5, Xtro\ankk1, Xtro\ank1, Xtro\ankdd1a, Xtro\cat2, Xtro\tnks, Xtro\trpc1, Xtro\asb7, Xtro\ank3, Xtro\trpc6, Xtro\ank2, Xtro\trpc2, Xtro\trpc3, Xtro\LOC100492885, Xtro\ankef1" "Mmus\Ankrd53, Mmus\Tnks, Mmus\Ankrd61, Mmus\Hace1, Mmus\Psmd10, Mmus\Ankrd65, Mmus\Ankef1, Mmus\Ankdd1a, Mmus\Trpc2, Mmus\Ankdd1b, Mmus\Trpc3, Mmus\Trpc1, Mmus\Ank1, Mmus\Trpc6, Mmus\Trpc5, Mmus\Invs, Mmus\Trpc7, Mmus\Asb7, Mmus\Ankrd60, Mmus\Ankrd52, Mmus\Tnks2, Mmus\Rnasel, Mmus\Pidd1, Mmus\Trpc4, Mmus\Ankk1, Mmus\Ankrd44, Mmus\Ankrd28, Mmus\Ankrd42, Mmus\Ank3, Mmus\Ank2" "Hsap\ANKDD1B, Hsap\ANKRD61, Hsap\ANKRD52, Hsap\ANKRD53, Hsap\ANK3, Hsap\TRPC6, Hsap\ANK1, Hsap\PIDD1, Hsap\TNKS2, Hsap\TRPC1, Hsap\ANKRD60, Hsap\ASB7, Hsap\ANK2, Hsap\ANKRD65, Hsap\ANKRD44, Hsap\PSMD10, Hsap\HACE1, Hsap\TRPC7, Hsap\INVS, Hsap\TNKS, Hsap\ANKDD1A, Hsap\TRPC3, Hsap\ANKK1, Hsap\ANKEF1, Hsap\TRPC4, Hsap\TRPC5, Hsap\RNASEL, Hsap\ANKRD28" " pharate adult stage , pupal stage | late " " macrochaeta &&of proboscis

, microchaeta

, mechanosensory sensory organ

, Johnston's organ

, leg sensillum

, macrochaeta

, chordotonal organ &&of haltere

" "neurophysiology defective,auditory perception defective,lethal - all die before end of embryonic stage,recessive,behavior defective,locomotor behavior defective,uncoordinated,some die during embryonic stage,wild-type,touch sensitivity defective,lethal - all die before end of larval stage,some die during third instar larval stage,touch perception defective,neuroanatomy defective,viable" "local interneuron of adult antennal lobe,antenna,adult antennal nerve,leg,macrochaeta,wing,arista,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0265627 CG44435 - http://flybase.org/reports/FBgn0265627 protein_coding_gene - - - "CG44435, CG15086" - CG44435 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002504 l(3)SG64 lethal (3) SG64 http://flybase.org/reports/FBgn0002504 - gene - - - "l(3)g30R, l(3)g131, l(3)SG64" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013498 l(1)LB lethal (1) of Luers and Belitz http://flybase.org/reports/FBgn0013498 - gene - - - l(1)LB - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053702 CG33702 - http://flybase.org/reports/FBgn0053702 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33702 IPR010512:Protein of unknown function DUF1091 CG33702 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050033 CG30033 - http://flybase.org/reports/FBgn0050033 protein_coding_gene - - - "BcDNA:RH63918, BcDNA:RH07028, CG30033" - CG30033 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032755 CG17344 - http://flybase.org/reports/FBgn0032755 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT10305, CG17344" - CG17344 11-Aug-17 DroID_v2017_08 - Scer\COM2 - - Mmus\Ikzf3 Hsap\IKZF3 viable FBgn0259266 C373 - http://flybase.org/reports/FBgn0259266 gene - - - C373 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta" FBgn0020353 anon-32ABa anon-32ABa http://flybase.org/reports/FBgn0020353 - gene - - - "503, anon-32ABa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042643 flexin flexin http://flybase.org/reports/FBgn0042643 gene - - - flexin - - 11-Aug-17 DroID_v2017_08 - - - - - - synapseunspecified FBgn0032040 CG13386 - http://flybase.org/reports/FBgn0032040 protein_coding_gene - - - CG13386 - CG13386 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0082347 HM421 HM421 http://flybase.org/reports/FBgn0082347 gene - - - HM421 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040107 lectin-21Ca lectin-21Ca http://flybase.org/reports/FBgn0040107 protein_coding_gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model "AC004573a, AC 004573A, CG2826, lectin-21Ca, Lectin-21Ca" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG2826 11-Aug-17 DroID_v2017_08 "Drer\clec11a, Drer\colec11, Drer\acanb, Drer\selp, Drer\clec3a, Drer\colec12, Drer\hbl1, Drer\clec3bb, Drer\hbl2, Drer\hbl4, Drer\hbl3, Drer\clec3ba, Drer\si:dkey-83f18.10" - "Cele\clec-149, Cele\clec-178" "Xtro\clec3b, Xtro\clec3a" "Mmus\Colec11, Mmus\Clec11a, Mmus\Clec3b, Mmus\Sell, Mmus\Colec10, Mmus\Sftpd, Mmus\Clec3a, Mmus\Mbl2, Mmus\Sftpa1, Mmus\Bcan, Mmus\Mbl1, Mmus\Vcan, Mmus\Acan" "Hsap\MBL2, Hsap\CLEC3B, Hsap\CLEC4A, Hsap\SFTPA1, Hsap\COLEC10, Hsap\VCAN, Hsap\CLEC11A, Hsap\BCAN, Hsap\CLEC3A, Hsap\SFTPA2, Hsap\SFTPD, Hsap\COLEC11, Hsap\ACAN" viable FBgn0003557 Su(dx) Suppressor of deltex http://flybase.org/reports/FBgn0003557 "FBgn0043511, FBgn0043512, FBgn0043513" protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from physical interaction with pyd Notch binding ; GO:0005112 | inferred from physical interaction with UniProtKB:P07207 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:16804 receptor internalization ; GO:0031623 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from genetic interaction with dx inferred from genetic interaction with N protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:16804 Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype inferred from genetic interaction with dx inferred from genetic interaction with N negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with UniProtKB:P07207 imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from direct assay wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype regulation of protein localization ; GO:0032880 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with UniProtKB:P10041 inferred from genetic interaction with UniProtKB:Q23985 imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype inferred from genetic interaction with N pupal development ; GO:0035209 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "Su(dx), Su(deltex), Su(Dx), CG4244, anon-WO0073329.4, anon-WO0073329.2, anon-WO0073329.1, ITCH, AIP4, su(dx), Itch, Su (Dx)" "IPR000008:C2 domain, IPR000569:HECT domain, IPR001202:WW domain" CG4244 11-Aug-17 DroID_v2017_08 "Drer\hecw1b, Drer\bag3, Drer\yap1, Drer\nedd4a, Drer\hecw2a, Drer\wwtr1, Drer\smurf1, Drer\LOC100334952, Drer\wwp2, Drer\itcha, Drer\nedd4l, Drer\hecw2b, Drer\smurf2, Drer\itchb" "Scer\RSP5, Scer\TOM1" "Cele\Y92H12A.2, Cele\wwp-1" "Xtro\bag3, Xtro\itch, Xtro\hecw1, Xtro\smurf1, Xtro\nedd4, Xtro\wwp2, Xtro\wwp1, Xtro\nedd4l" "Mmus\Bag3, Mmus\Gas7, Mmus\Smurf2, Mmus\Wwp1, Mmus\Wwp2, Mmus\Itch, Mmus\Hecw2, Mmus\Nedd4l, Mmus\Yap1, Mmus\Hecw1, Mmus\Smurf1, Mmus\Nedd4" "Hsap\SMURF1, Hsap\HECW1, Hsap\NEDD4L, Hsap\YAP1, Hsap\GAS7, Hsap\NEDD4, Hsap\ITCH, Hsap\HECW2, Hsap\WWP2, Hsap\WWP1, Hsap\SMURF2, Hsap\BAG3" pupal stage wing | restricted

"visible,recessive,heat sensitive,somatic clone,partially lethal - majority die,lethal,viable" "wing vein,crossvein,follicle cell,somatic clone,follicle cell & nucleus | somatic clone,heat sensitive,wing vein L4,wing vein L5,wing vein L2,ectopic,wing margin,wing disc,tarsal segment,sex comb,supernumerary,tarsal segment & jointptc-559.1,wing,wing vein L3,leg,dorsocentral bristle" FBgn0037889 scpr-A SCP-containing protein A http://flybase.org/reports/FBgn0037889 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "SCPR-A, bs03f04.y1, CG5207, scpr-A, scp-A, cg5207" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG5207 11-Aug-17 DroID_v2017_08 "Drer\crispld1b, Drer\LOC101883528, Drer\crispld2, Drer\glipr1b, Drer\crispld1a, Drer\glipr2l, Drer\r3hdml, Drer\LOC100536500, Drer\pi15b, Drer\glipr2, Drer\pi15a" "Scer\PRY1, Scer\PRY3, Scer\PRY2" "Cele\scl-12, Cele\scl-7, Cele\scl-19, Cele\scl-10, Cele\scl-18, Cele\scl-23, Cele\scl-21, Cele\scl-20, Cele\scl-6, Cele\scl-3, Cele\scl-11, Cele\scl-5, Cele\scl-14, Cele\scl-17, Cele\scl-2, Cele\scl-13, Cele\scl-9, Cele\scl-8, Cele\scl-1, Cele\scl-15, Cele\lon-1" "Xtro\crisp2, Xtro\r3hdml, Xtro\MGC108118, Xtro\crisp3, Xtro\glipr2, Xtro\crispld2, Xtro\pi15, Xtro\crisp1" "Mmus\Glipr1, Mmus\Crispld2, Mmus\R3hdml, Mmus\Crisp4, Mmus\Crisp1, Mmus\Crisp3, Mmus\Crisp2, Mmus\Pi15, Mmus\Pi16, Mmus\Clec18a, Mmus\Glipr2, Mmus\Glipr1l1, Mmus\Crispld1, Mmus\Glipr1l2" "Hsap\CRISP2, Hsap\GLIPR1, Hsap\PI15, Hsap\CLEC18A, Hsap\GLIPR2, Hsap\CLEC18B, Hsap\PI16, Hsap\GLIPR1L1, Hsap\CRISP1, Hsap\GLIPR1L2, Hsap\CRISPLD1, Hsap\CRISPLD2, Hsap\R3HDML, Hsap\CLEC18C" viable FBgn0061110 l(3)S006930b lethal (3) S006930b http://flybase.org/reports/FBgn0061110 gene - - - "0069/30, l(3)S006930b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0062596 Mod(var)1535 Mod(var)1535 http://flybase.org/reports/FBgn0062596 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1535, Mod(var)1535" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0019750 l(1)815-3 lethal (1) 815-3 http://flybase.org/reports/FBgn0019750 - gene - - - l(1)815-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085652 CG41491 - http://flybase.org/reports/FBgn0085652 protein_coding_gene - - - CG41491 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085584 CG41262 - http://flybase.org/reports/FBgn0085584 protein_coding_gene - - - CG41262 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085422 CG34393 - http://flybase.org/reports/FBgn0085422 protein_coding_gene Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | inferred from sequence or structural similarity with HGNC:24246 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from sequence or structural similarity with HGNC:24246 cellular_component ; GO:0005575 | no biological data available "CG34393, CG15405, CG8829, Dm_2L:14421" "IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR023578:Ras guanine nucleotide exchange factor domain" CG34393 11-Aug-17 DroID_v2017_08 "Drer\rasgef1ba, Drer\rasgef1bb" Scer\CDC25 "Cele\R05G6.10, Cele\sos-1" "Xtro\rasgef1b, Xtro\rasgef1a" "Mmus\Rasgef1b, Mmus\Rasgef1a, Mmus\Rasgef1c" "Hsap\RASGEF1A, Hsap\RASGEF1C, Hsap\RASGEF1B" viable FBgn0261381 mtTFB1 Mitochondrial Transcription Factor B1 http://flybase.org/reports/FBgn0261381 protein_coding_gene "rRNA (adenine-N6,N6-)-dimethyltransferase activity ; GO:0000179 | inferred from biological aspect of ancestor with PANTHER:PTN000197843 transcription cofactor activity ; GO:0003712 | inferred from sequence or structural similarity with UniProtKB:Q9H5Q4" "rRNA modification ; GO:0000154 | inferred from electronic annotation with InterPro:IPR020596, InterPro:IPR020598 transcription from mitochondrial promoter ; GO:0006390 | inferred from sequence or structural similarity with UniProtKB:Q9H5Q4 regulation of translation ; GO:0006417 | inferred from mutant phenotype" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q9H5Q4 mitochondrion ; GO:0005739 | inferred from direct assay "mtTFB1, d-mtTFB1, CG42631, CG7319, d-TFB1M, TFB1" "IPR011530:Ribosomal RNA adenine dimethylase, IPR001737:Ribosomal RNA adenine methyltransferase KsgA/Erm, IPR020596:Ribosomal RNA adenine methylase transferase, conserved site, IPR020598:Ribosomal RNA adenine methylase transferase, N-terminal, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR023165:rRNA adenine dimethylase-like" CG42631 11-Aug-17 DroID_v2017_08 Drer\tfb1m Scer\DIM1 Cele\tfbm-1 Xtro\tfb1m Mmus\Tfb1m Hsap\TFB1M FBgn0050497 CG30497 - http://flybase.org/reports/FBgn0050497 protein_coding_gene - - cytosol ; GO:0005829 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CG30497, CG1383, EP(2)2618, BEST:LD33067, NEST:bs36c04, CG1557, anon-WO0118547.176, CG30947" IPR012937:FAM46 family CG30497 11-Aug-17 DroID_v2017_08 "Drer\fam46c, Drer\fam46bb, Drer\fam46ba, Drer\fam46ab, Drer\fam46aa" - "Cele\ZK1010.4, Cele\F53F8.4, Cele\F13H8.5, Cele\T20G5.12, Cele\F26G1.5, Cele\pqn-44, Cele\fig-1, Cele\C56C10.4, Cele\F18C5.9, Cele\F26G1.9, Cele\Y53F4B.25, Cele\dao-2, Cele\F17C11.22, Cele\C42D4.3, Cele\T20G5.13, Cele\pqn-32, Cele\F35B3.4, Cele\T23F11.6, Cele\Y57G11C.42" "Xtro\fam46b, Xtro\fam46c, Xtro\fam46a" "Mmus\Fam46c, Mmus\Fam46a, Mmus\Fam46b, Mmus\Fam46d" "Hsap\FAM46A, Hsap\FAM46D, Hsap\FAM46C, Hsap\FAM46B" "viable,fertile,neuroanatomy defective" longitudinal connective FBgn0060513 l(3)S104011b lethal (3) S104011b http://flybase.org/reports/FBgn0060513 gene - - - "1040/11, l(3)S104011b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002819 ms(2)3R male sterile (2) 3R http://flybase.org/reports/FBgn0002819 - gene - - - ms(2)3R - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile,cytokinesis defective,male" "spermatozoon,spermatid,Nebenkern,Nebenkern derivative,spermatocyte" FBgn0051459 CG31459 - http://flybase.org/reports/FBgn0051459 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs29d02, NEST:bs03f05, BcDNA:AT26603, CG31459" - CG31459 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029012 l(3)77CDm lethal (3) 77CDm http://flybase.org/reports/FBgn0029012 gene - - - l(3)77CDm - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032125 Cpr30B Cuticular protein 30B http://flybase.org/reports/FBgn0032125 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr30B, CG3818, DmelCpr30B" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG3818 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "viable,visible,body color defective" mesothoracic tergum FBgn0030441 CG2209 - http://flybase.org/reports/FBgn0030441 protein_coding_gene - - - "anon-WO0140519.110, CG2209" - CG2209 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267864 CR46152 - http://flybase.org/reports/FBgn0267864 pseudogene_attribute - - - "CR46152, CG12717-related" - CR46152 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015566 zaro zarolho http://flybase.org/reports/FBgn0015566 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available zaro - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267995 CR46262 - http://flybase.org/reports/FBgn0267995 non_protein_coding_gene - - - CR46262 - CR46262 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060912 l(3)S042806b lethal (3) S042806b http://flybase.org/reports/FBgn0060912 gene - - - "0428/06, l(3)S042806b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0053240 Ste:CG33240 Ste:CG33240 http://flybase.org/reports/FBgn0053240 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG32605, CG33240, Ste:CG33240" "IPR016149:Casein kinase II, regulatory subunit, alpha-helical, IPR000704:Casein kinase II, regulatory subunit" CG33240 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0026359 Su(Raf)43B Su(Raf)43B http://flybase.org/reports/FBgn0026359 - gene - - - Su(Raf)43B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062619 Mod(var)1200 Mod(var)1200 http://flybase.org/reports/FBgn0062619 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1200, Mod(var)1200" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0065195 l(2)SH2324 lethal (2) SH2324 http://flybase.org/reports/FBgn0065195 gene - - - "l(2)SH2324, l(2)SH2 2324" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014394 tete tete http://flybase.org/reports/FBgn0014394 - gene - - - "te, c47, tete" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0033020 COX4L Cytochrome c oxidase subunit 4-like http://flybase.org/reports/FBgn0033020 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000076140 cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P13073 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProtKB:P13073 mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000076140" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000076140 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P13073 "IV, BcDNA:AT07685, COX IV, CG10396, cox4, COXIV, CX41, CX42, COX4L" "IPR004203:Cytochrome c oxidase subunit IV family, IPR013288:Cytochrome c oxidase subunit IV" CG10396 11-Aug-17 DroID_v2017_08 "Drer\cox4i2, Drer\cox4i1l, Drer\cox4i1" "Scer\MTC3, Scer\COX5B, Scer\COX5A" Cele\W09C5.8 "Xtro\cox4i2, Xtro\cox4i1, Xtro\LOC100127750" "Mmus\Cox4i1, Mmus\Cox4i2" "Hsap\COX4I1, Hsap\COX4I2" viable FBgn0002511 l(3)Sp1 lethal (3) Sp1 http://flybase.org/reports/FBgn0002511 - gene - - - l(3)Sp1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053631 CG33631 - http://flybase.org/reports/FBgn0053631 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12808, CG33631" IPR010512:Protein of unknown function DUF1091 CG33631 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040665 CG13593 - http://flybase.org/reports/FBgn0040665 protein_coding_gene - - - CG13593 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061127 l(3)S003302b lethal (3) S003302b http://flybase.org/reports/FBgn0061127 gene - - - "0033/02, l(3)S003302b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024696 e(if)1 enhancer of inflated 1 http://flybase.org/reports/FBgn0024696 - gene - - - e(if)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033519 CG11825 - http://flybase.org/reports/FBgn0033519 protein_coding_gene - copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype - "BcDNA:RE25483, CG11825, dHIG1" "IPR007667:Hypoxia induced protein, domain" CG11825 11-Aug-17 DroID_v2017_08 "Drer\higd2a, Drer\higd1a" Scer\RCF1 "Cele\T20D3.6, Cele\M05D6.5" "Xtro\higd1b, Xtro\higd1c, Xtro\higd2a, Xtro\higd1a" "Mmus\Methig1, Mmus\Higd1b, Mmus\Higd2a, Mmus\Higd1c, Mmus\Higd1a" "Hsap\HIGD1C, Hsap\HIGD2A, Hsap\CCDC13, Hsap\HIGD1A, Hsap\HIGD1B" viable FBgn0022067 l(2)k07914 lethal (2) k07914 http://flybase.net/reports/FBgn0022067.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0263019 CR43314 - http://flybase.org/reports/FBgn0263019 non_protein_coding_gene - - - "CR43314, pri-mir-263a" - CR43314 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002265 l(3)69Ad lethal (3) 69Ad http://flybase.org/reports/FBgn0002265 - gene - - - "rsg27, l(3)rsg27, l(3)62-3, l(3)69Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060511 l(3)S104207b lethal (3) S104207b http://flybase.org/reports/FBgn0060511 gene - - - "1042/07, l(3)S104207b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011850 tRNA:Glu-TTC-1-4 transfer RNA:Glutamic acid-TTC 1-4 http://flybase.org/reports/FBgn0011850 "FBgn0003771, FBgn0011846, FBgn0050451, FBgn0060239" tRNA_gene GAA codon-amino acid adaptor activity ; GO:0033459 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033459 cytosol ; GO:0005829 | inferred by curator from GO:0033459 "CR30451, glu-tRNA-4, AE002787.trna6-GluTTC, tRNA:E4, tRNA:E:TTC:AE002787-c, tRNA:glu4:56Fc, tRNA:Glu, chr2R.trna64-GluTTC, tRNA:Glu-TTC-1-4, tRNA:E4:56Fc, tRNA-Glu-TTC-1-4, GAA, tRNA-Glu4 (56Fc)" - CR30451 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017379 l(1)EA65 lethal (1) EA65 http://flybase.org/reports/FBgn0017379 - gene - - - "EA65, l(1)EA65" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022350 anon-Y anon-Y http://flybase.org/reports/FBgn0022350 - gene - - - "gene Y, anon-Y" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061481 snafu snafu http://flybase.org/reports/FBgn0061481 gene - - - snafu - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031335 CG5565 - http://flybase.org/reports/FBgn0031335 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 "CG5565, 28557659" "IPR023198:Phosphoglycolate phosphatase, domain 2, IPR006439:HAD hydrolase, subfamily IA, IPR023214:HAD-like domain" CG5565 11-Aug-17 DroID_v2017_08 Drer\pudp "Scer\GPP2, Scer\DOG1, Scer\YKL033W-A, Scer\DOG2, Scer\GPP1" Cele\R151.10 Xtro\pudp Mmus\Hdhd1a Hsap\PUDP viable FBgn0266455 CG45080 - http://flybase.org/reports/FBgn0266455 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45080 - CG45080 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004431 LysX Lysozyme X http://flybase.org/reports/FBgn0004431 "FBgn0002575, FBgn0063089" protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 lysozyme activity ; GO:0003796 | inferred from sequence or structural similarity - - "LysX, lysX, CG9120, BcDNA:LP09906" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CG9120 11-Aug-17 DroID_v2017_08 "Drer\LOC100334363, Drer\LOC100536671, Drer\lyz" - - Xtro\MGC89221 "Mmus\Spaca5, Mmus\Lyzl4, Mmus\Lyzl1, Mmus\Lyz1, Mmus\Lyz2, Mmus\Spaca1, Mmus\Spaca3, Mmus\Spaca4, Mmus\Spaca7, Mmus\Lyzl6, Mmus\1700016D06Rik, Mmus\Lalba, Mmus\9530003J23Rik" "Hsap\SPACA5B, Hsap\SPACA7, Hsap\SPACA1, Hsap\SPACA3, Hsap\LYZL6, Hsap\LYZL1, Hsap\LYZL2, Hsap\LALBA, Hsap\LYZL4, Hsap\SPACA5, Hsap\SPACA4, Hsap\LYZ" " pupal stage | early , embryonic stage -- adult stage , larval stage | third instar " embryonic/larval midgut

FBgn0001867 l(1)X27 lethal (1) X27 http://flybase.org/reports/FBgn0001867 - gene - - - l(1)X27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "ventral nerve cord,presumptive embryonic/larval central nervous system,gastrula embryo,ventral furrow,embryonic/larval midgut,embryonic/larval hindgut,presumptive embryonic/larval digestive system,embryonic/larval somatic muscle,ectoderm" FBgn0004017 wl whirly http://flybase.org/reports/FBgn0004017 - gene - - - wl - - 11-Aug-17 DroID_v2017_08 - - - - - - visible acrostichal bristle FBgn0002320 l(3)85Ed lethal (3) 85Ed http://flybase.org/reports/FBgn0002320 - gene - - - l(3)85Ed - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001496 l(1)10Bj lethal (1) 10Bj http://flybase.org/reports/FBgn0001496 - gene - - - "10Bj, l(1)G23, l(1)10Bj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0002081 l(2)49Fj lethal (2) 49Fj http://flybase.org/reports/FBgn0002081 - gene - - - "vr-19, l(2)vr19, l(2)49Fj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,non-suppressor of variegation,dominant" FBgn0034309 CG14498 - http://flybase.org/reports/FBgn0034309 protein_coding_gene - - - CG14498 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033205 CG2064 - http://flybase.org/reports/FBgn0033205 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - endomembrane system ; GO:0012505 | inferred from direct assay "BcDNA:SD07613, CG2064" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG2064 11-Aug-17 DroID_v2017_08 "Drer\zgc:153441, Drer\rdh12l, Drer\dhrs13l1, Drer\dhrs13a.3, Drer\rdh12, Drer\dhrs13a.2, Drer\si:ch211-107o10.3, Drer\si:dkey-94e7.2, Drer\flj13639, Drer\si:ch211-165b10.3, Drer\dhrs12, Drer\si:dkey-23o4.6, Drer\zgc:112332, Drer\dhrsx, Drer\rdh14a, Drer\ascc1, Drer\rdh14b, Drer\si:dkey-73n8.3, Drer\si:dkey-174n20.1, Drer\cbr1l, Drer\zgc:64106, Drer\dhrs13a.1, Drer\cbr1" "Scer\YNL181W, Scer\GPI11, Scer\YKL107W, Scer\ENV9" "Cele\E04F6.15, Cele\C27D8.4, Cele\dhs-22, Cele\DC2.5" "Xtro\dhrsx, Xtro\rdh13, Xtro\dhrs12, Xtro\rdh11, Xtro\ascc1, Xtro\rdh14, Xtro\dhrs13" "Mmus\Wwox, Mmus\1700003E16Rik, Mmus\Dhrs13, Mmus\Cbr3, Mmus\Rdh14, Mmus\Dhrsx, Mmus\Rdh12, Mmus\Rdh13, Mmus\Cbr1, Mmus\Rdh11, Mmus\Ascc1" "Hsap\OSTC, Hsap\CBR3, Hsap\CBR1, Hsap\RDH13, Hsap\DHRS12, Hsap\C2orf81, Hsap\DHRS13, Hsap\RDH12, Hsap\DHRSX, Hsap\RDH14, Hsap\RDH11" viable FBgn0265423 CG44335 - http://flybase.org/reports/FBgn0265423 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44335, lincRNA.706, lincRNA.707" - CG44335 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029158 Las Lipoic acid synthase http://flybase.org/reports/FBgn0029158 protein_coding_gene "lipoate synthase activity ; GO:0016992 | inferred from electronic annotation with InterPro:IPR003698 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR003698" lipoate biosynthetic process ; GO:0009107 | inferred from electronic annotation with InterPro:IPR003698 - "CG5231, Las" "IPR003698:Lipoyl synthase, IPR006638:Elongator protein 3/MiaB/NifB, IPR007197:Radical SAM, IPR013785:Aldolase-type TIM barrel, IPR031691:Lipoyl synthase, N-terminal" CG5231 11-Aug-17 DroID_v2017_08 Drer\lias Scer\LIP5 Cele\M01F1.3 Xtro\lias Mmus\Lias Hsap\LIAS viable FBgn0032914 CG14397 - http://flybase.org/reports/FBgn0032914 protein_coding_gene - - - CG14397 - CG14397 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025821 I-t inhibitor-t http://flybase.org/reports/FBgn0025821 - protein_coding_gene protein phosphatase inhibitor activity ; GO:0004864 | inferred from direct assay negative regulation of protein dephosphorylation ; GO:0035308 | inferred from direct assay - "pp1d6, CG14719, I-t" - CG14719 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036712 brv2 brivido-2 http://flybase.org/reports/FBgn0036712 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR003915 calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity detection of mechanical stimulus ; GO:0050982 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype detection of temperature stimulus involved in thermoception ; GO:0050960 | inferred from mutant phenotype cellular response to cold ; GO:0070417 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 "CG16793, CT33194, brv2" "IPR003915:Polycystic kidney disease type 2 protein, IPR013122:Polycystin cation channel, PKD1/PKD2" CG16793 11-Aug-17 DroID_v2017_08 "Drer\pkd2l1, Drer\pkd1b, Drer\LOC100537993, Drer\pkd1a" - "Cele\lov-1, Cele\pkd-2" Xtro\pkd1 "Mmus\Pkd1, Mmus\Pkd1l3, Mmus\Pkd1l2, Mmus\Pkdrej, Mmus\Pkd2l2, Mmus\Pkd1l1" "Hsap\PKD1L3, Hsap\PKDREJ, Hsap\PKD1L1, Hsap\PKD1L2, Hsap\PKD2L2" "cold stress response defective,recessive" FBgn0014383 scy scratched eye http://flybase.org/reports/FBgn0014383 - gene - - - scy - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011440 l(3)j13B3 lethal (3) j13B3 http://flybase.org/reports/FBgn0011440 - gene - - - l(3)j13B3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266160 CR44866 - http://flybase.org/reports/FBgn0266160 non_protein_coding_gene - - - CR44866 - CR44866 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054054 CG34054 - http://flybase.org/reports/FBgn0054054 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1079, HDC05792, CG34054" - CG34054 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267083 CR45527 - http://flybase.org/reports/FBgn0267083 non_protein_coding_gene - - - CR45527 - CR45527 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036495 CG33259 - http://flybase.org/reports/FBgn0036495 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG7489, CG33259" "IPR002919:Trypsin Inhibitor-like, cysteine rich domain" CG33259 11-Aug-17 DroID_v2017_08 - - "Cele\spi-1, Cele\F32D8.3, Cele\K07A1.6, Cele\Y26D4A.12, Cele\F36H9.4, Cele\C25E10.7, Cele\F53C11.9, Cele\T01D3.3, Cele\C53B7.2, Cele\swm-1, Cele\B0238.12, Cele\C25E10.8, Cele\C10G8.4" - - - viable DRSC10854 E 0.176172967 -0.310144143 -0.559548569 1.643617035 -0.247992136 -0.605057689 FBgn0265926 CR44715 - http://flybase.org/reports/FBgn0265926 non_protein_coding_gene - - - CR44715 - CR44715 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027961 l(3)S146004 lethal (3) S146004 http://flybase.org/reports/FBgn0027961 gene - - - "1460/04, l(3)S146004" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0086064 snoRNA:Me28S-G3113b - http://flybase.org/reports/FBgn0086064 snoRNA_gene - - - "snoRNA:Me28S-G3113b, Me28S-Gm3113b, CR34693" - CR34693 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024644 l(2)k11002 lethal (2) k11002 http://flybase.org/reports/FBgn0024644 - gene - - - "110/2, l(2)k11002" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053795 CG33795 - http://flybase.org/reports/FBgn0053795 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33795 IPR010512:Protein of unknown function DUF1091 CG33795 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267202 CR45642 - http://flybase.org/reports/FBgn0267202 non_protein_coding_gene - - - CR45642 - CR45642 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033813 fsd fates-shifted http://flybase.org/reports/FBgn0033813 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with bcd inferred from physical interaction with SkpA larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from direct assay SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from physical interaction with SkpA "fsd, CG12765, FBXO14" "IPR001810:F-box domain, IPR026509:Transmembrane protein 183" CG12765 11-Aug-17 DroID_v2017_08 Drer\tmem183a - - Xtro\tmem183a Mmus\Tmem183a "Hsap\TMEM183B, Hsap\TMEM183A" "viable,embryonic/larval segmentation phenotype,maternal effect,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage" cephalic furrow FBgn0004419 me31B maternal expression at 31B http://flybase.org/reports/FBgn0004419 FBgn0022123 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI2 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA binding ; GO:0003723 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with papi cytoplasmic mRNA processing body assembly ; GO:0033962 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from genetic interaction with Ge-1 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs pole cell formation ; GO:0007279 | inferred from genetic interaction with tud inferred from genetic interaction with vas regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype P granule ; GO:0043186 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic stress granule ; GO:0010494 | inferred from biological aspect of ancestor with PANTHER:PTN000619958 "Me31B, CG4916, ME31B, DmRH3, l(2)k06607, me31B, Me31b, Dhh1p/Me31b, Mat31B, DDX6, me31b" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4916 11-Aug-17 DroID_v2017_08 "Drer\ddx6, Drer\ddx61, Drer\tomm40" Scer\DHH1 Cele\cgh-1 Xtro\ddx6 Mmus\Ddx6 Hsap\DDX6 "viable,lethal,recessive,wild-type,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,learning defective" "egg chamber,germline clone,germline cell,nurse cell & nucleus | germ-line clone,oocyte,ring canal" DRSC03569 E -0.783340184 0.85447016 -3.574064433 -3.884511917 0.418355931 1.238734598 FBgn0041004 CG17715 - http://flybase.org/reports/FBgn0041004 protein_coding_gene - - - "CG18603, BcDNA:RE63764, BcDNA:RE07178, CG17715" IPR019537:Transmembrane protein 65 CG17715 11-Aug-17 DroID_v2017_08 Drer\tmem65 - "Cele\tag-321, Cele\C03B8.3" - Mmus\Tmem65 Hsap\TMEM65 viable FBgn0260872 CG42582 - http://flybase.org/reports/FBgn0260872 protein_coding_gene - - - "CG42582, mdcds_57926" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034328 IM23 Immune induced molecule 23 http://flybase.org/reports/FBgn0034328 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to bacterium ; GO:0009617 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern Toll signaling pathway ; GO:0008063 | non-traceable author statement antibacterial humoral response ; GO:0019731 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "DIM 23, CG15066, BcDNA:RH67033, IM23, DIM-23" IPR013172:Immune-induced protein Dim CG15066 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004743 l(3)85Dj lethal (3) 85Dj http://flybase.org/reports/FBgn0004743 - gene - - - l(3)85Dj - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002346 l(3)87Cb lethal (3) 87Cb http://flybase.org/reports/FBgn0002346 - gene - - - "l(3)SzB, l(3)87Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037399 Or83c Odorant receptor 83c http://flybase.org/reports/FBgn0037399 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "83c, DOR116, 83D.1, CG15581, Or83c" "IPR004117:Olfactory receptor, insect" CG15581 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,neurophysiology defective,viable,chemosensitive behavior defective" antennal intermediate sensillum I2 FBgn0005407 l(1)11Ag lethal (1) 11Ag http://flybase.org/reports/FBgn0005407 - gene - - - l(1)11Ag - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025748 l(3)95Ay lethal (3) 95Ay http://flybase.org/reports/FBgn0025748 - gene - - - l(3)95Ay - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016871 l(2)39Ad lethal (2) 39Ad http://flybase.org/reports/FBgn0016871 "FBgn0016872, FBgn0016873, FBgn0016874" gene - - - "l(2)39Ag, l(2)39Af, l(2)39Ae, l(2)39Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085332 CG34303 - http://flybase.org/reports/FBgn0085332 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34303 IPR010512:Protein of unknown function DUF1091 CG34303 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082963 snoRNA:Psi28S-3378 snoRNA:Psi28S-3378 http://flybase.org/reports/FBgn0082963 snoRNA_gene - - - "snoRNA:Psi28S-3378, Psi28S-3378, psi28S-3378, Psi 28S-3378, CR34549" - CR34549 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014356 ms(3)HB366 ms(3)HB366 http://flybase.org/reports/FBgn0014356 - gene - - - ms(3)HB366 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066365 dyl dusky-like http://flybase.org/reports/FBgn0066365 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with dy apical constriction ; GO:0003383 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype cell-matrix adhesion ; GO:0007160 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay "CG15013, dyl" IPR001507:Zona pellucida domain CG15013 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001031, Drer\si:ch211-103f14.3, Drer\si:ch211-229d2.5, Drer\zgc:153932" - "Cele\cutl-5, Cele\cutl-29, Cele\cut-5, Cele\cutl-8, Cele\ram-5, Cele\cutl-4, Cele\cutl-10, Cele\cut-1, Cele\cutl-24, Cele\cutl-20, Cele\cutl-15, Cele\dpy-1, Cele\cutl-6, Cele\cutl-7, Cele\cut-3, Cele\cutl-28, Cele\cutl-12, Cele\cutl-16, Cele\F46G11.6, Cele\cutl-11, Cele\cutl-25, Cele\cutl-14, Cele\cutl-2, Cele\cutl-22, Cele\cutl-26, Cele\cut-4, Cele\cut-6, Cele\cutl-9, Cele\cutl-1, Cele\cutl-3, Cele\cutl-13, Cele\cutl-19, Cele\T01D1.8" "Xtro\MGC89178, Xtro\thdl17, Xtro\thdl18" - - "viable,fertile,visible" trichogen cell FBgn0039585 CG1894 - http://flybase.org/reports/FBgn0039585 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002717" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002717" - "CG1894, dmHAG407" "IPR002717:Histone acetyltransferase domain, MYST-type, IPR016181:Acyl-CoA N-acyltransferase" CG1894 11-Aug-17 DroID_v2017_08 "Drer\kat6a, Drer\kat5a, Drer\kat7b, Drer\kat8, Drer\kat5b, Drer\kat7a, Drer\kat6b" "Scer\ESA1, Scer\SAS2, Scer\SAS3" "Cele\mys-2, Cele\mys-4, Cele\mys-1" "Xtro\kat8, Xtro\trim69.1, Xtro\kat5, Xtro\xnf7, Xtro\kat7" "Mmus\Kat7, Mmus\Kat6b, Mmus\Kat5, Mmus\Kat6a, Mmus\Kat8" "Hsap\KAT7, Hsap\KAT5, Hsap\KAT6A, Hsap\KAT6B, Hsap\KAT8" viable FBgn0267156 CR45596 - http://flybase.org/reports/FBgn0267156 non_protein_coding_gene - - - CR45596 - CR45596 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016846 l(1)N26 lethal (1) N26 http://flybase.org/reports/FBgn0016846 - gene - - - "l(1)N26, N26" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033165 CG11113 - http://flybase.org/reports/FBgn0033165 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | non-traceable author statement extracellular space ; GO:0005615 | inferred from sequence model CG11113 - CG11113 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036351 CG14107 - http://flybase.org/reports/FBgn0036351 protein_coding_gene - - - CG14107 - CG14107 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC10110 IE 0.313546561 1.681444017 0.258710283 -2.116526508 -0.133401931 0.339957725 FBgn0070056 19 19 http://flybase.org/reports/FBgn0070056 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "#19, 19" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042141 CG18818 - http://flybase.org/reports/FBgn0042141 protein_coding_gene - - - CG18818 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267658 CR45996 - http://flybase.org/reports/FBgn0267658 non_protein_coding_gene - - - "CR45996, lincRNA.807" - CR45996 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085753 28SrRNA-Psi:CR40596 28S ribosomal RNA pseudogene:CR40596 http://flybase.org/reports/FBgn0085753 pseudogene_attribute - - - "CR40596, 28SrRNA-Psi:CR40596" - CR40596 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014165 four-play four-play http://flybase.org/reports/FBgn0014165 - gene - - - four-play - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0035280 Cpr62Bb Cuticular protein 62Bb http://flybase.org/reports/FBgn0035280 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr62Bb, CG13935, DmelCpr62Bb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG13935 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0032911 tadr torn and diminished rhabdomeres http://flybase.org/reports/FBgn0032911 protein_coding_gene L-amino acid transmembrane transporter activity ; GO:0015179 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 - integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 "CG9264, tadr, torn" - CG9264 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-120h9.1, Drer\slc7a6, Drer\slc7a7, Drer\slc7a11, Drer\si:ch73-352p4.8" "Scer\TAT1, Scer\MUP1, Scer\MUP3" "Cele\aat-9, Cele\aat-7, Cele\aat-8, Cele\aat-4, Cele\aat-6, Cele\aat-5, Cele\Y53F4B.12" - "Mmus\Slc7a14, Mmus\Slc7a11, Mmus\Slc7a6, Mmus\Slc7a7" "Hsap\SLC7A14, Hsap\SLC7A11, Hsap\SLC7A6, Hsap\SLC7A7" "viable,neurophysiology defective,fertile" rhabdomere FBgn0267231 CR45671 - http://flybase.org/reports/FBgn0267231 non_protein_coding_gene - - - CR45671 - CR45671 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064163 l(4)A6 lethal (4) A6 http://flybase.org/reports/FBgn0064163 gene - - - l(4)A6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065966 l(2)SH0013 lethal (2) SH0013 http://flybase.org/reports/FBgn0065966 gene - - - "l(2)SH0013, l(2)SH2 0013" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029959 Rab39 Rab39 http://flybase.org/reports/FBgn0029959 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 protein binding ; GO:0005515 | inferred from physical interaction with BicD inferred from physical interaction with CG17360 inferred from physical interaction with unc-104 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Golgi apparatus ; GO:0005794 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 neuronal cell body ; GO:0043025 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay "AAF46271, DmRab39, CG12156, Rab39, rab39, 24640395" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12156 11-Aug-17 DroID_v2017_08 "Drer\rab39bb, Drer\si:dkey-34d22.2, Drer\rab42b, Drer\LOC100330257, Drer\rab42a, Drer\si:dkey-34d22.5, Drer\rab39ba" "Scer\YPT31, Scer\YPT32" Cele\rab-39 "Xtro\rab39b, Xtro\rab39a" "Mmus\Rab39, Mmus\Rab39b, Mmus\Rab42" "Hsap\RAB42, Hsap\RAB39A, Hsap\RAB39B" "viable,visible" mesothoracic tergum FBgn0002129 l(2)K202 lethal (2) K202 http://flybase.org/reports/FBgn0002129 - gene - - - l(2)K202 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060866 l(3)S047222 lethal (3) S047222 http://flybase.org/reports/FBgn0060866 gene - - - "0472/22, l(3)S047222" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011444 l(3)j15E7 lethal (3) j15E7 http://flybase.org/reports/FBgn0011444 - gene - - - l(3)j15E7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002347 l(3)87Cc lethal (3) 87Cc http://flybase.org/reports/FBgn0002347 - gene - - - "l(3)SzC, l(3)87Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0065351 l(2)SH1798 lethal (2) SH1798 http://flybase.org/reports/FBgn0065351 gene - - - "l(2)SH1798, l(2)SH2 1798" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260603 2L0948 - http://flybase.org/reports/FBgn0260603 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L0948 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0001641 l(1)dn21 lethal (1) discs normal 21 http://flybase.org/reports/FBgn0001641 - gene - - - "l(1)d.norm.-21, l(1)dn21" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0261802 CG42748 - http://flybase.org/reports/FBgn0261802 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B - lateral plasma membrane ; GO:0016328 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG42748, CG15216, CG15217, anon-WO0140519.28, CG6448" - CG42748 11-Aug-17 DroID_v2017_08 "Drer\unm_hu7912, Drer\zmp:0000000794" - Cele\ajm-1 Xtro\c9orf172 Mmus\Gm996 Hsap\C9orf172 FBgn0020785 rr red ring http://flybase.org/reports/FBgn0020785 - gene - - - rr - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,eye color defective" "eye,ommatidium,pigment cell" FBgn0032769 CG10750 - http://flybase.org/reports/FBgn0032769 protein_coding_gene - - - CG10750 "IPR025252:Domain of unknown function DUF4200, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG10750 11-Aug-17 DroID_v2017_08 Drer\cfap73 - - Xtro\cfap73 "Mmus\Ccdc42, Mmus\Cfap73" "Hsap\CCDC42, Hsap\CFAP73" viable FBgn0032515 loqs loquacious http://flybase.org/reports/FBgn0032515 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Dcr-1 double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity "pre-miRNA processing ; GO:0031054 | inferred from direct assay germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype pre-miRNA processing ; GO:0031054 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype production of small RNA involved in gene silencing by RNA ; GO:0070918 | inferred from direct assay production of siRNA involved in RNA interference ; GO:0030422 | inferred from direct assay miRNA metabolic process ; GO:0010586 | inferred from direct assay production of siRNA involved in RNA interference ; GO:0030422 | inferred from mutant phenotype regulation of production of small RNA involved in gene silencing by RNA ; GO:0070920 | inferred from direct assay dosage compensation by hyperactivation of X chromosome ; GO:0009047 | inferred from genetic interaction with roX2, roX1 female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype" RISC complex ; GO:0016442 | colocalizes_with inferred from physical interaction with Dcr-1 cytoplasm ; GO:0005737 | inferred from direct assay "Loqs, TRBP, R3D1-S, CG6866, R3D1-L, cg6866, r3d1, loqs, R3D1, loquacious, LOQS, dRax, loq" "IPR014720:Double-stranded RNA-binding domain, IPR032478:Staufen, C-terminal" CG6866 11-Aug-17 DroID_v2017_08 "Drer\stau2, Drer\stau1, Drer\tarbp2, Drer\prkra" - "Cele\adr-1, Cele\D2005.1, Cele\stau-1" "Xtro\stau1, Xtro\tarbp2, Xtro\prkra, Xtro\stau2" "Mmus\Tarbp2, Mmus\Stau1, Mmus\Prkra, Mmus\Stau2" "Hsap\PRKRA, Hsap\STAU2, Hsap\STAU1, Hsap\TARBP2" "viable,female sterile,recessive,male sterile,partially,male semi-sterile,locomotor behavior defective,neuroanatomy defective,lethal,short lived,conditional,lethal - all die before end of embryonic stage,paternal effect,some die during embryonic stage,rescuable maternal effect,non-suppressor of variegation,male fertile,fertile" "testis,ovary,ovariole,germarium,female germline stem cell,follicle cell,spectrosome,egg chamber,ventral nerve cord commissure,longitudinal connective,eye,retina,conditional,lamina,germline clone,dorsal appendage,germline stem cell" FBgn0051709 CG31709 - http://flybase.org/reports/FBgn0051709 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:LP04712, CG31709" - CG31709 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000417 darky darky http://flybase.org/reports/FBgn0000417 - gene - - - "da, darky, dar" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male sterile,partially lethal - majority die,viable,male,poor,body color defective" "cuticle,wing,adult cuticle" FBgn0050395 CG30395 - http://flybase.org/reports/FBgn0050395 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG30395 - CG30395 11-Aug-17 DroID_v2017_08 "Drer\map6b, Drer\map6a" "Scer\USO1, Scer\BBC1" - Xtro\map6 Mmus\Map6 Hsap\MAP6 viable FBgn0265546 CR44396 - http://flybase.org/reports/FBgn0265546 non_protein_coding_gene - - - CR44396 - CR44396 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030642 CG15642 - http://flybase.org/reports/FBgn0030642 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15642 "IPR019184:Uncharacterised protein family, transmembrane-17" CG15642 11-Aug-17 DroID_v2017_08 "Drer\tmem17, Drer\zgc:112294" - - - Mmus\Tmem17 Hsap\TMEM17 "viable,body color defective" mesothoracic tergum FBgn0039425 CG5432 - http://flybase.org/reports/FBgn0039425 protein_coding_gene fructose-bisphosphate aldolase activity ; GO:0004332 | inferred from electronic annotation with InterPro:IPR000741 glycolytic process ; GO:0006096 | inferred from electronic annotation with InterPro:IPR000741 - CG5432 "IPR000741:Fructose-bisphosphate aldolase, class-I, IPR013785:Aldolase-type TIM barrel" CG5432 11-Aug-17 DroID_v2017_08 "Drer\aldob, Drer\aldocb, Drer\aldoca, Drer\aldoab, Drer\aldoaa" - "Cele\aldo-1, Cele\aldo-2" "Xtro\aldoa, Xtro\aldob, Xtro\aldoc" "Mmus\Aldob, Mmus\Aldoart2, Mmus\Aldoa, Mmus\Aldoart1, Mmus\Aldoc" "Hsap\ALDOA, Hsap\ALDOB, Hsap\ALDOC" viable DRSC15799 E 1.242056616 -0.219548144 1.788522727 -1.628003832 -0.489431626 -0.311132544 FBgn0022223 l(2)k03204 lethal (2) k03204 http://flybase.net/reports/FBgn0022223.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0011786 l(3)06264 lethal (3) 06264 http://flybase.org/reports/FBgn0011786 - gene - - - "l(3)04264, l(3)06264" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0001480 l(1)9Fh lethal (1) 9Fh http://flybase.org/reports/FBgn0001480 - gene - - - "l(1)G4, l(1)EF433, l(1)9Fh" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260003 Dys Dystrophin http://flybase.org/reports/FBgn0260003 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 WW domain binding ; GO:0050699 | inferred from physical interaction with Dg cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC:12635 inferred from sequence or structural similarity with HGNC:2928 inferred from sequence or structural similarity with HGNC:3032 actin binding ; GO:0003779 | inferred from sequence or structural similarity structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1ZA89 imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from direct assay imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from direct assay establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from direct assay muscle organ development ; GO:0007517 | inferred from mutant phenotype dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from physical interaction with Dg cytoskeleton ; GO:0005856 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity with HGNC:12635 inferred from sequence or structural similarity with HGNC:2928 inferred from sequence or structural similarity with HGNC:3032 dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity cell cortex ; GO:0005938 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity "DmDYS, DmDLP, Dys, dmDp186, CG7243, CG7240, CG17750, CG31175, CG7344, Dp205, DLP2, CG34157, DLP, dmDLP, DLP3, DLP1, DLP186, GI3046716, det, Dp186, dys, IDLP, Dp117, dmDys, Dystrophin" "IPR000433:Zinc finger, ZZ-type, IPR001202:WW domain, IPR001589:Actinin-type actin-binding domain, conserved site, IPR001715:Calponin homology domain, IPR002017:Spectrin repeat, IPR011992:EF-hand domain pair, IPR015153:EF-hand domain, type 1, IPR015154:EF-hand domain, type 2, IPR018159:Spectrin/alpha-actinin" CG34157 11-Aug-17 DroID_v2017_08 "Drer\drp2, Drer\pkhd1l1, Drer\dmd, Drer\si:ch211-244a23.1" - "Cele\dys-1, Cele\dyb-1" "Xtro\utrn, Xtro\drp2" "Mmus\Pkhd1l1, Mmus\Pkhd1, Mmus\Dmd, Mmus\Drp2, Mmus\Utrn" "Hsap\PKHD1L1, Hsap\DMD, Hsap\DRP2, Hsap\UTRN, Hsap\PKHD1" DRSC16220 EK -0.820606314 -0.583094626 1.600842411 -0.130368388 3.986557362 0.617476153 FBgn0039209 REPTOR Repressed by TOR http://flybase.org/reports/FBgn0039209 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR004827 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with REPTOR-BP" "regulation of multicellular organismal metabolic process ; GO:0044246 | inferred from mutant phenotype TORC1 signaling ; GO:0038202 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern response to starvation ; GO:0042594 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "anon-WO0153538.65, CG13624, REPTOR, DM23, DM24, reptor" IPR004827:Basic-leucine zipper domain CG13624 11-Aug-17 DroID_v2017_08 Drer\crebrf - - - Mmus\Crebrf Hsap\CREBRF viable DRSC24359 K -0.255281191 0.541229535 0.121267756 0.799991361 2.435586401 0.489685221 FBgn0028873 CG31771 - http://flybase.org/reports/FBgn0028873 protein_coding_gene - - - "DS05899.6, BG:DS05899.6, CG31771" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0002254 l(3)68Ef lethal (3) 68Ef http://flybase.org/reports/FBgn0002254 - gene - - - "rsg16, l(3)rsg16, l(3)68Ef" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265013 ed::Nrg - http://flybase.org/reports/FBgn0265013 engineered_fusion_gene - - - ed::Nrg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039987 CR12798 - http://flybase.org/reports/FBgn0039987 pseudogene_attribute - - - "CG12798, SEK1/MKK4, CT38386, CR12798" - CR12798 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052299 CG32299 - http://flybase.org/reports/FBgn0052299 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs19a11, BcDNA:AT26229, CG32299" - CG32299 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001126 gou gourd http://flybase.org/reports/FBgn0001126 - gene molecular_function ; GO:0003674 | no biological data available dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gou - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0051360 CG31360 - http://flybase.org/reports/FBgn0051360 protein_coding_gene - - - "BcDNA:RE06652, CG31360" IPR028036:Domain of unknown function DUF4536 CG31360 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026718 fu12 fu12 http://flybase.org/reports/FBgn0026718 - protein_coding_gene 1-acylglycerol-3-phosphate O-acyltransferase activity ; GO:0003841 | inferred from electronic annotation with InterPro:IPR004552 acylglycerol O-acyltransferase activity ; GO:0016411 | inferred from biological aspect of ancestor with PANTHER:PTN000046632 phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR004552 behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR004552 "CG17608, fu12, AGPAT1, AGPAT2" "IPR002123:Phospholipid/glycerol acyltransferase, IPR004552:1-acyl-sn-glycerol-3-phosphate acyltransferase" CG17608 11-Aug-17 DroID_v2017_08 Drer\agpat2 Scer\SLC1 "Cele\acl-1, Cele\acl-2" "Xtro\agpat2, Xtro\agpat1" "Mmus\Agpat2, Mmus\Agpat1" "Hsap\AGPAT1, Hsap\AGPAT2" "viable,fertile,hyperactive,conditional,chemical resistant" FBgn0015440 l(1)5Da lethal (1) 5Da http://flybase.org/reports/FBgn0015440 - gene - - - l(1)5Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032845 CG10747 - http://flybase.org/reports/FBgn0032845 protein_coding_gene glycosylphosphatidylinositol diacylglycerol-lyase activity ; GO:0047396 | inferred from electronic annotation with InterPro:IPR003633 phosphoric diester hydrolase activity ; GO:0008081 | inferred from electronic annotation with InterPro:IPR017946 glycerophospholipid metabolic process ; GO:0006650 | inferred from electronic annotation with InterPro:IPR003633 - "38B.13, CG10747" "IPR000909:Phosphatidylinositol-specific phospholipase C, X domain, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR003633:Phospholipase C, variant-surface-glycoprotein" CG10747 11-Aug-17 DroID_v2017_08 "Drer\plcxd2, Drer\zgc:112023, Drer\plcxd1, Drer\plcxd3, Drer\si:dkey-66a8.7, Drer\LOC100151335, Drer\zgc:64065" - Cele\F38E9.1 "Xtro\plcxd3, Xtro\plcxd2, Xtro\plcxd1" "Mmus\Plcxd3, Mmus\Plcxd1, Mmus\Plcxd2" "Hsap\PLCXD1, Hsap\PLCXD3, Hsap\PLCXD2" "viable,fertile" FBgn0023002 laph larval phototaxis http://flybase.org/reports/FBgn0023002 - gene - - - laph - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000460 Daughter-killer Daughter killer http://flybase.org/reports/FBgn0000460 - gene - - - "Daughter-killer, Dk" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264809 Arr1::TEV\NIa - http://flybase.org/reports/FBgn0264809 engineered_fusion_gene - - - "arrestin-TEV protease, Arr1::Zzzz\NIa, Arr1::TEV\NIa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028090 l(3)S082106 lethal (3) S082106 http://flybase.org/reports/FBgn0028090 gene - - - "0821/06, l(3)S082106" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032702 CG10376 - http://flybase.org/reports/FBgn0032702 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000002164 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002164 protein dephosphorylation ; GO:0006470 | non-traceable author statement nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002164 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002164 "PP2C, CG10376" "IPR001932:PPM-type phosphatase domain, IPR015655:Protein phosphatase 2C family" CG10376 11-Aug-17 DroID_v2017_08 "Drer\ilkap, Drer\ppm1k, Drer\si:ch211-149b19.3, Drer\tab1, Drer\ppm1f, Drer\ppm1ab, Drer\ppm1bb, Drer\ppm1la, Drer\ppm1e, Drer\ppm1lb, Drer\ppm1da" "Scer\PTC2, Scer\PTC6, Scer\PTC1, Scer\PTC4" "Cele\Y54F10BM.1, Cele\ppm-1, Cele\fem-2, Cele\ppm-2" "Xtro\ilkap, Xtro\tab1, Xtro\ppm1l, Xtro\ppm1k, Xtro\ppm1f, Xtro\ppm1a, Xtro\ppm1d, Xtro\ppm1e, Xtro\ppm1b" "Mmus\Ilkap, Mmus\Ppm1k, Mmus\Pp2d1, Mmus\Ppm1l, Mmus\Ppm1d, Mmus\Ppm1b, Mmus\Ppm1a, Mmus\Ppm1f, Mmus\Ppm1e, Mmus\Tab1" "Hsap\PPM1L, Hsap\PPM1A, Hsap\ILKAP, Hsap\PP2D1, Hsap\PPM1F, Hsap\PPM1E, Hsap\PPM1K, Hsap\TAB1, Hsap\PPM1D" viable FBgn0032871 CG2611 - http://flybase.org/reports/FBgn0032871 protein_coding_gene - - - "38D.27, CG2611" "IPR008590:Protein of unknown function DUF872, transmembrane" CG2611 11-Aug-17 DroID_v2017_08 "Drer\tmem230a, Drer\tmem230b, Drer\tmem134" - - Xtro\tmem230 Mmus\Tmem230 "Hsap\TMEM230, Hsap\TMEM134" viable FBgn0036179 CG7368 - http://flybase.org/reports/FBgn0036179 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000003381" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR027775 phagocytosis ; GO:0006909 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 CG7368 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027775:C2H2- zinc finger protein family subset" CG7368 11-Aug-17 DroID_v2017_08 Drer\LOC101882293 "Scer\MET31, Scer\RPN4, Scer\MET32" "Cele\mnm-2, Cele\fezf-1, Cele\che-1" Xtro\znf605 "Mmus\Zfp446, Mmus\Zfp444, Mmus\Zkscan17, Mmus\Zfp641, Mmus\Zfp110, Mmus\Zkscan6, Mmus\Zfp369, Mmus\Zfp202, Mmus\Zkscan2, Mmus\Hivep3, Mmus\Zscan29, Mmus\Zfp316, Mmus\Zscan5b, Mmus\Zfp174, Mmus\Zscan18" "Hsap\PEG3, Hsap\ZSCAN29, Hsap\ZNF316, Hsap\ZNF641, Hsap\ZSCAN18, Hsap\ZNF18, Hsap\ZBTB7B, Hsap\ZNF174, Hsap\ZSCAN1, Hsap\HIVEP3, Hsap\ZSCAN5B, Hsap\ZNF202, Hsap\ZNF496, Hsap\ZSCAN32, Hsap\ZNF444, Hsap\ZNF75A, Hsap\ZNF446, Hsap\ZSCAN5A, Hsap\ZKSCAN2" viable DRSC10826 IK -1.935542915 0.849347215 0.452241778 0.681696603 3.012509062 1.129085403 FBgn0052613 CG32613 - http://flybase.org/reports/FBgn0052613 protein_coding_gene - - - "BcDNA:GM13088, CG32613" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031254 CG13692 - http://flybase.org/reports/FBgn0031254 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006689, InterPro:IPR024156" small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR024156 cellular_component ; GO:0005575 | no biological data available CG13692 "IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024156:Small GTPase superfamily, ARF type" CG13692 11-Aug-17 DroID_v2017_08 "Drer\arl1, Drer\arl16" Scer\ARL1 Cele\arl-1 "Xtro\arl16, Xtro\arl1" "Mmus\Arl16, Mmus\Arl1" "Hsap\ARL1, Hsap\ARL16" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0260302 GSd330 - http://flybase.org/reports/FBgn0260302 gene - - - GSd330 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0082337 HM696 HM696 http://flybase.org/reports/FBgn0082337 gene - - - HM696 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011109 l(1)Q70 lethal (1) Q70 http://flybase.org/reports/FBgn0011109 FBgn0010210 gene - - - l(1)Q70 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263621 CG43630 - http://flybase.org/reports/FBgn0263621 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43630 - CG43630 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023163 Su(mg)1-4 Suppressor of modifier of gypsy 1-4 http://flybase.org/reports/FBgn0023163 - gene - - - Su(mg)1-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264634 carbuncle carbuncle http://flybase.org/reports/FBgn0264634 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - carbuncle - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0003287 Rst(2)amd alpha methyl dopa-resistant on 2 http://flybase.org/reports/FBgn0003287 - gene - - - Rst(2)amd - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0046763 CG17278 - http://flybase.org/reports/FBgn0046763 protein_coding_gene - negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with dsh inferred from genetic interaction with sgg - "BcDNA:SD04019, CG17278" IPR002350:Kazal domain CG17278 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,visible,lethal" "wing,wing blade,adult abdomen" DRSC15216 E -0.091745187 0.114555744 1.038112668 -2.358883087 0.101292823 -0.660009055 FBgn0002191 l(3)63Bb lethal (3) 63Bb http://flybase.org/reports/FBgn0002191 - gene - - - l(3)63Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035833 CG7565 - http://flybase.org/reports/FBgn0035833 protein_coding_gene - - - "CT23145, CG7565" "IPR000601:PKD domain, IPR011106:Seven cysteines, N-terminal, IPR013980:MANSC domain, IPR013783:Immunoglobulin-like fold, IPR022409:PKD/Chitinase domain" CG7565 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-215d9.1, Drer\si:ch73-160p18.3, Drer\si:ch211-193k19.1, Drer\lrp11" - Cele\Y75B8A.10 Xtro\kiaa0319 "Mmus\D130043K22Rik, Mmus\AU040320, Mmus\Lrp11" "Hsap\KIAA0319L, Hsap\KIAA0319, Hsap\LRP11" viable FBgn0004497 fs(1)gammab3 female sterile (1) gammab3 http://flybase.org/reports/FBgn0004497 - gene - - - fs(1)gammab3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040354 CG14418 - http://flybase.org/reports/FBgn0040354 protein_coding_gene - - - "EG:BACR43E12.5, CG14418" - CG14418 11-Aug-17 DroID_v2017_08 - - - - - - "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0016859 l(1)N6 lethal (1) N6 http://flybase.org/reports/FBgn0016859 - gene - - - "l(1)N6, N6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011877 tRNA:His-GTG-2-1Psi transfer RNA:Histidine-GTG 2-1 pseudogene http://flybase.org/reports/FBgn0011877 "FBgn0050253, FBgn0060290" pseudogene_attribute - - - "His-tRNA, AE002787.trna36-Undet, tRNA:-?:AE002787, CR30253, tRNA:hisPsi, chr2R.trna18-Undet???, tRNA-Und-NNN-2-1, tRNA:His-GTG-2-1Psi, tRNA:HPsi" - CR30253 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082593 eunuch eunuch http://flybase.org/reports/FBgn0082593 gene - - - eunuch - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265578 CG44405 - http://flybase.org/reports/FBgn0265578 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44405 - CG44405 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085311 CG34282 - http://flybase.org/reports/FBgn0085311 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG34282, CG7710" IPR002557:Chitin binding domain CG34282 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036193 CG14135 - http://flybase.org/reports/FBgn0036193 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612 - - CG14135 "IPR006612:Zinc finger, C2CH-type" CG14135 11-Aug-17 DroID_v2017_08 - - - - Mmus\Thap7 "Hsap\THAP8, Hsap\THAP7" "viable,planar polarity defective" FBgn0020890 Su(osk)P16 Suppressor of oskar P16 http://flybase.org/reports/FBgn0020890 - gene - - - "P16, Su(osk)P16" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065541 l(2)SH1060 lethal (2) SH1060 http://flybase.org/reports/FBgn0065541 gene - - - "l(2)SH1060, l(2)SH2 1060" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052447 CG32447 - http://flybase.org/reports/FBgn0052447 protein_coding_gene glutamate receptor activity ; GO:0008066 | inferred from biological aspect of ancestor with PANTHER:PTN001173581 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mGluR "regulation of synaptic transmission, glutamatergic ; GO:0051966 | inferred from biological aspect of ancestor with PANTHER:PTN001173581 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mGluR adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway ; GO:0007196 | inferred from biological aspect of ancestor with PANTHER:PTN001527784" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001173583 presynaptic membrane ; GO:0042734 | inferred from biological aspect of ancestor with PANTHER:PTN001527784 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with mGluR "CG7155, CG14571, anon-WO0170980.77, anon-WO0170980.76, CG32447" "IPR017978:GPCR family 3, C-terminal" CG32447 11-Aug-17 DroID_v2017_08 "Drer\grm1b, Drer\grm1a, Drer\grm5b, Drer\grm4, Drer\grm6a, Drer\grm8a, Drer\grm5a, Drer\grm6b, Drer\grm8b" - "Cele\mgl-2, Cele\C30A5.10" - "Mmus\Grm4, Mmus\Grm5, Mmus\Grm6, Mmus\Grm1, Mmus\Grm8, Mmus\Grm7" "Hsap\GRM1, Hsap\GRM4, Hsap\GRM5, Hsap\GRM6, Hsap\GRM7, Hsap\GRM8" viable FBgn0004159 l(2)51Eb lethal (2) 51Eb http://flybase.org/reports/FBgn0004159 - gene - - - l(2)51Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic" FBgn0085783 CR41111 - http://flybase.org/reports/FBgn0085783 non_protein_coding_gene - - - CR41111 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016709 Reg-14 Rhythmically expressed gene 14 http://flybase.org/reports/FBgn0016709 - gene - - - "Dreg-14, Reg-14" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | late , adult stage " adult head

FBgn0261286 Mat89Ba Maternal transcript 89Ba http://flybase.org/reports/FBgn0261286 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with MGI:MGI:2140151 cellular response to starvation ; GO:0009267 | inferred from expression pattern rRNA processing ; GO:0006364 | inferred from sequence or structural similarity with SGD:S000003322 tRNA export from nucleus ; GO:0006409 | inferred from biological aspect of ancestor with PANTHER:PTN000427561 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000427561 neurogenesis ; GO:0022008 | inferred from mutant phenotype small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000427561 condensed nuclear chromosome ; GO:0000794 | inferred from sequence or structural similarity with UniProtKB:Q8R5K4 UTP-C complex ; GO:0034456 | inferred from biological aspect of ancestor with PANTHER:PTN000427561 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with MGI:MGI:2140151 inferred from sequence or structural similarity with SGD:S000003322 CURI complex ; GO:0032545 | inferred from biological aspect of ancestor with PANTHER:PTN000427561 "CG12785, Mat89Ba" IPR005554:Nrap protein CG12785 11-Aug-17 DroID_v2017_08 Drer\nol6 Scer\UTP22 Cele\nol-6 Xtro\nol6 Mmus\Nol6 Hsap\NOL6 " adult stage , adult stage && oogenesis stage | stage >=S10 , adult stage && oogenesis stage | stage S9-10 " " ovary

, oocyte

, nurse cell

" FBgn0267521 18SrRNA-Psi:CR45861 18S ribosomal RNA pseudogene:CR45861 http://flybase.org/reports/FBgn0267521 pseudogene_attribute - - - "18SrRNA-Psi:CR45861, CR45861" - CR45861 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036916 Mtr3 Mtr3 http://flybase.org/reports/FBgn0036916 protein_coding_gene - "rRNA 3'-end processing ; GO:0031125 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 nuclear mRNA surveillance ; GO:0071028 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' ; GO:0034427 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 rRNA catabolic process ; GO:0016075 | inferred from biological aspect of ancestor with PANTHER:PTN000237327 U4 snRNA 3'-end processing ; GO:0034475 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 polyadenylation-dependent snoRNA 3'-end processing ; GO:0071051 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 cytoplasmic exosome (RNase complex) ; GO:0000177 | inferred from biological aspect of ancestor with PANTHER:PTN000237328 nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000003390 inferred from direct assay exosome (RNase complex) ; GO:0000178 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG8025, dMtr3, Mtr3, mtr3" "IPR001247:Exoribonuclease, phosphorolytic domain 1, IPR015847:Exoribonuclease, phosphorolytic domain 2, IPR027408:PNPase/RNase PH domain, IPR020568:Ribosomal protein S5 domain 2-type fold" CG8025 11-Aug-17 DroID_v2017_08 "Drer\exosc6, Drer\exosc4" "Scer\MTR3, Scer\SKI6" "Cele\tin-9.2, Cele\exos-4.2" "Xtro\rarg, Xtro\exosc4" "Mmus\Exosc6, Mmus\Exosc4" "Hsap\EXOSC4, Hsap\EXOSC6" "partially lethal - majority die,visible" trichogen cell DRSC10953 E 0.15676239 -0.796504727 0.51526968 -1.841064335 0.357879212 0.561750107 FBgn0085708 CG41582 - http://flybase.org/reports/FBgn0085708 protein_coding_gene - - - CG41582 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262063 EG28 - http://flybase.org/reports/FBgn0262063 gene - - - EG28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052499 Cda4 Chitin deacetylase-like 4 http://flybase.org/reports/FBgn0052499 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011330 chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR002509, InterPro:IPR011330 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 neurogenesis ; GO:0022008 | inferred from mutant phenotype" perivitelline space ; GO:0098595 | inferred from direct assay "CG13238, CG9558, CG9557, CG12447, BcDNA:RE51076, CG32499, Cda4, DmCDA4" "IPR002557:Chitin binding domain, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel" CG32499 11-Aug-17 DroID_v2017_08 - - "Cele\F48E3.8, Cele\lgx-1" - - - "viable,lethal,neuroanatomy defective,fertile" ganglion mother cell FBgn0019843 anon-pp84 anon-pp84 http://flybase.org/reports/FBgn0019843 - gene - - - "pp84, anon-pp84" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026660 l(2)12A9 lethal (2) 12A9 http://flybase.org/reports/FBgn0026660 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)12A9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0046874 Pif1B PFTAIRE-interacting factor 1B http://flybase.org/reports/FBgn0046874 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Eip63E biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "PIF-1B, CG9808, CG32940, BcDNA:GH12504, Pif1, CG33720, Pif1B, CG33719/CG33720" - CG33720 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263867 CR43714 - http://flybase.org/reports/FBgn0263867 non_protein_coding_gene - - - "CR43714, lincRNA.47" - CR43714 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019769 l(1)53 lethal (1) 53 http://flybase.org/reports/FBgn0019769 - gene - - - l(1)53 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035973 CG17179 - http://flybase.org/reports/FBgn0035973 protein_coding_gene - - - CG17179 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265693 CR44500 - http://flybase.org/reports/FBgn0265693 non_protein_coding_gene - - - "lincRNA.960, CR44500" - CR44500 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039691 IntS11 Integrator 11 http://flybase.org/reports/FBgn0039691 protein_coding_gene - mRNA polyadenylation ; GO:0006378 | inferred from sequence or structural similarity with protein_id:AAF00224 snRNA 3'-end processing ; GO:0034472 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:26052 mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with protein_id:AAF00224 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from sequence or structural similarity with protein_id:AAF00224 integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:26052 "CG1972, IntS11, dRC-68, Int11" "IPR001279:Metallo-beta-lactamase, IPR011108:Zn-dependent metallo-hydrolase, RNA specificity domain, IPR022712:Beta-Casp domain" CG1972 11-Aug-17 DroID_v2017_08 "Drer\cpsf3l, Drer\cpsf3" Scer\YSH1 Cele\F10B5.8 "Xtro\cpsf3l, Xtro\cpsf3" "Mmus\Cpsf3, Mmus\Cpsf3l" "Hsap\CPSF3, Hsap\CPSF3L" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0069166 mcl(3)Z1483 mcl(3)Z1483 http://flybase.org/reports/FBgn0069166 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1483 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0013340 Su(var)2-24 Su(var)2-24 http://flybase.org/reports/FBgn0013340 - gene - - - Su(var)2-24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant" FBgn0262650 l(2)47A9-5 lethal (2) 47A9-5 http://flybase.org/reports/FBgn0262650 gene - - - l(2)47A9-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003323 sby small body http://flybase.org/reports/FBgn0003323 - gene - - - "sby-6a, sby-61, sby" - - 11-Aug-17 DroID_v2017_08 - - - - - - "small body,viable,reduced,fertile,body color defective" FBgn0069147 mcl(3)Z3822 mcl(3)Z3822 http://flybase.org/reports/FBgn0069147 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3822 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0015398 kasa kasa http://flybase.org/reports/FBgn0015398 - gene - - - kasa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259412 C474.1 - http://flybase.org/reports/FBgn0259412 gene - - - C474.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0023510 Rbcn-3B Rabconnectin-3B http://flybase.org/reports/FBgn0023510 - protein_coding_gene - "vacuolar acidification ; GO:0007035 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001871492 "EG:86E4.3, Rbcn-3B, FK39, CG17766" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site" CG17766 11-Aug-17 DroID_v2017_08 Drer\wdr7 - Cele\rbc-2 "Xtro\wdr72, Xtro\wdr7" "Mmus\Wdr72, Mmus\Wdr7" "Hsap\WDR72, Hsap\WDR7" "lethal,recessive,viable,visible,body color defective" "follicle cell,somatic clone,mesothoracic tergum" FBgn0028182 l(3)S024151 lethal (3) S024151 http://flybase.org/reports/FBgn0028182 gene - - - "0241/51, l(3)S024151" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0265906 CR44695 - http://flybase.org/reports/FBgn0265906 non_protein_coding_gene - - - CR44695 - CR44695 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023000 mth methuselah http://flybase.org/reports/FBgn0023000 - protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | traceable author statement G-protein coupled receptor activity ; GO:0004930 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VXN2 G-protein coupled peptide receptor activity ; GO:0008528 | inferred from physical interaction with sun protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A0A1F4 inferred from physical interaction with UniProtKB:P05623 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity peptide binding ; GO:0042277 | inferred from physical interaction with sun cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 response to oxidative stress ; GO:0006979 | non-traceable author statement response to heat ; GO:0009408 | non-traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay response to starvation ; GO:0042594 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype response to starvation ; GO:0042594 | non-traceable author statement determination of adult lifespan ; GO:0008340 | traceable author statement aging ; GO:0007568 | traceable author statement determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from direct assay response to paraquat ; GO:1901562 | inferred from mutant phenotype response to heat ; GO:0009408 | traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | traceable author statement aging ; GO:0007568 | inferred from mutant phenotype response to reactive oxygen species ; GO:0000302 | inferred from mutant phenotype response to starvation ; GO:0042594 | traceable author statement integral component of membrane ; GO:0016021 | traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from direct assay "Mth, CG6936, MTH, mth" "IPR017981:GPCR, family 2-like, IPR000832:GPCR, family 2, secretin-like, IPR010596:Methuselah, N-terminal domain, IPR023311:Methuselah ectodomain, domain 2" CG6936 11-Aug-17 DroID_v2017_08 "Drer\LOC100538279, Drer\adgrf6, Drer\adgrg1, Drer\adgrl1a, Drer\adgre5b.3, Drer\adgrg2a, Drer\adgrl3.1, Drer\LOC100535070, Drer\fbn2a, Drer\LOC101884341, Drer\adgrl4, Drer\adgrl2a, Drer\fbn2b, Drer\adgrg3, Drer\adgrf3a, Drer\adgrg6, Drer\adgrg11, Drer\adgrd2, Drer\LOC101886975, Drer\adgre10, Drer\LOC100537181, Drer\adgrf11, Drer\adgrg4a, Drer\adgre14" - - "Xtro\adgrd1, Xtro\adgre5, Xtro\adgrg1, Xtro\adgrl1, Xtro\adgrf1, Xtro\adgrf3, Xtro\gpr157, Xtro\adgrv1" "Mmus\Adgrg4, Mmus\Adgrl3, Mmus\Adgrf2, Mmus\Adgrd1, Mmus\Adgrg5, Mmus\Adgrf4, Mmus\Adgrg1, Mmus\Adgrf1, Mmus\Adgrl1, Mmus\Adgre4, Mmus\Adgrg2, Mmus\Adgrg6, Mmus\Adgrf3, Mmus\Adgre5, Mmus\Adgrg7, Mmus\Adgre1, Mmus\Adgrl2, Mmus\Adgrg3, Mmus\Adgrl4, Mmus\Adgrf5" "Hsap\ADGRG6, Hsap\ADGRF3, Hsap\ADGRL3, Hsap\ADGRF2, Hsap\FBN3, Hsap\ADGRL4, Hsap\ADGRG2, Hsap\ADGRE1, Hsap\ADGRL1, Hsap\ADGRD2, Hsap\ADGRF5, Hsap\ADGRE2, Hsap\ADGRG3, Hsap\ADGRF4, Hsap\ADGRF1, Hsap\ADGRE3, Hsap\ADGRL2, Hsap\ADGRG7, Hsap\ADGRG4, Hsap\ADGRG5, Hsap\ADGRD1, Hsap\ADGRE5, Hsap\ADGRG1" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,neurophysiology defective,stress response defective,neuroanatomy defective,long lived,chemical resistant,fertile,wild-type" "synapse,synaptic vesicle,male germline stem cell" FBgn0053641 CG33641 - http://flybase.org/reports/FBgn0053641 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33641 IPR010512:Protein of unknown function DUF1091 CG33641 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040798 CG13069 - http://flybase.org/reports/FBgn0040798 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG13069 - CG13069 11-Aug-17 DroID_v2017_08 "Drer\si:zfos-1505d6.3, Drer\zp2.6, Drer\si:dkey-19b23.15, Drer\sat2a, Drer\sat2b, Drer\pimr131, Drer\zp2.5, Drer\sat1b, Drer\sat1a.2, Drer\zp2l1, Drer\LOC101883245" - "Cele\H37A05.4, Cele\D2023.4, Cele\VH15N14R.1, Cele\mltn-9, Cele\mltn-12, Cele\Y9D1A.2, Cele\mltn-10, Cele\Y39B6A.9, Cele\F20B6.7" "Xtro\sat1, Xtro\zp4, Xtro\zp4.2, Xtro\sat2" "Mmus\Zp1, Mmus\Satl1, Mmus\Sat1, Mmus\Sat2, Mmus\LOC102639543" "Hsap\ZP1, Hsap\ZP4, Hsap\SAT2, Hsap\SAT1, Hsap\SATL1" viable FBgn0031077 CG15618 - http://flybase.org/reports/FBgn0031077 protein_coding_gene molecular_function ; GO:0003674 | no biological data available tRNA methylation ; GO:0030488 | inferred from sequence or structural similarity with SGD:S000004872 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000004872 CG15618 "IPR016024:Armadillo-type fold, IPR019442:Domain of unknown function DUF2428, death-receptor-like, IPR011989:Armadillo-like helical" CG15618 11-Aug-17 DroID_v2017_08 "Drer\thada, Drer\si:ch211-225b11.4" Scer\TRM732 Cele\Y92H12A.5 Xtro\thada Mmus\Thada Hsap\THADA "viable,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0266313 CR44978 - http://flybase.org/reports/FBgn0266313 non_protein_coding_gene - - - CR44978 - CR44978 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016838 l(1)MZ6 lethal (1) MZ6 http://flybase.org/reports/FBgn0016838 - gene - - - "l(1)MZ6, M6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261061 Sfp96F Seminal fluid protein 96F http://flybase.org/reports/FBgn0261061 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay Sfp96F - CG42609 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065629 l(2)SH0788 lethal (2) SH0788 http://flybase.org/reports/FBgn0065629 gene - - - "l(2)SH0788, l(2)SH2 0788" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028959 Au Auricular http://flybase.org/reports/FBgn0028959 gene - - - Au - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" eye FBgn0030578 CG5347 - http://flybase.org/reports/FBgn0030578 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:7112 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:7112 cellular_component ; GO:0005575 | no biological data available CG5347 "IPR000571:Zinc finger, CCCH-type, IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR018957:Zinc finger, C3HC4 RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5347 11-Aug-17 DroID_v2017_08 "Drer\rnf141, Drer\mkrn4, Drer\mkrn2, Drer\mkrn1" Scer\LEE1 "Cele\Y55F3AM.6, Cele\ccch-1" "Xtro\rnf141, Xtro\mkrn2, Xtro\mkrn3, Xtro\mkrn1" "Mmus\Mkrn1, Mmus\Rnf141, Mmus\Mkrn3, Mmus\Mkrn2" "Hsap\MKRN1, Hsap\RNF141, Hsap\MKRN3, Hsap\MKRN2" viable FBgn0033594 CG13226 - http://flybase.org/reports/FBgn0033594 protein_coding_gene - - - CG13226 - CG13226 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011675 ner nervig http://flybase.org/reports/FBgn0011675 - gene - - - ner - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262686 CG43156 - http://flybase.org/reports/FBgn0262686 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43156, lincRNA.980" - CG43156 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011938 tRNA:Asn-GTT-1-1 transfer RNA:Asparagine-GTT 1-1 http://flybase.org/reports/FBgn0011938 "FBgn0003759, FBgn0050305, FBgn0050513, FBgn0060130" tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "Asn8, Asn-tRNA-8, tRNA[Asn], AE002769.trna8-AsnGTT, tRNA:N:GTT:AE002769-d, tRNA:asn5:42Ah, CR30305, CR30513, chr2R.trna99-AsnGTT, tRNA-Asn-GTT-1-1, tRNA:Asn-GTT-1-1, tRNA:N5:42Ah, AAC" - CR30513 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002457 l(3)SG10 lethal (3) SG10 http://flybase.org/reports/FBgn0002457 - gene - - - "l(3)m27, l(3)SG10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033323 CG12376 - http://flybase.org/reports/FBgn0033323 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004837 "anon-WO0140519.77, CG12376" IPR004837:Sodium/calcium exchanger membrane region CG12376 11-Aug-17 DroID_v2017_08 "Drer\slc8b1, Drer\slc24a4b" "Scer\ECM27, Scer\YDL206W" "Cele\ncx-6, Cele\ncx-9, Cele\ncx-7, Cele\ncx-8, Cele\ncx-10" Xtro\slc8b1 "Mmus\Slc8b1, Mmus\Slc24a3, Mmus\Slc24a4" "Hsap\SLC24A4, Hsap\SLC24A3, Hsap\SLC8B1" viable FBgn0053147 Hs3st-A Heparan sulfate 3-O sulfotransferase-A http://flybase.org/reports/FBgn0053147 protein_coding_gene [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity ; GO:0008467 | inferred from sequence or structural similarity with UniProtKB:O14792 - - "CG15076, CG15075, CG30123, CG15074, CG30124, Hs3st-A, CG33147, lincRNA.S3111, dHS3OSTA" "IPR000863:Sulfotransferase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG33147 11-Aug-17 DroID_v2017_08 "Drer\hs3st1, Drer\hs3st4, Drer\hs3st3l, Drer\hs3st3b1a, Drer\hs3st1l1, Drer\si:dkey-121b10.7, Drer\hs3st2, Drer\hs3st3b1b, Drer\hs3st1l2" - "Cele\hst-3.2, Cele\hst-3.1" "Xtro\hs3st2, Xtro\hs3st1, Xtro\LOC100125092, Xtro\hs3st6, Xtro\hs3st5" "Mmus\Hs3st6, Mmus\Hs3st2, Mmus\Hs3st5, Mmus\Hs3st3a1, Mmus\Hs3st4, Mmus\Hs3st1, Mmus\Hs3st3b1" "Hsap\HS3ST5, Hsap\HS3ST1, Hsap\HS3ST6, Hsap\HS3ST4, Hsap\HS3ST2, Hsap\HS3ST3B1, Hsap\HS3ST3A1" "lethal,viable,fertile" FBgn0005757 l(1)TK401 lethal (1) TK401 http://flybase.org/reports/FBgn0005757 - gene - - - "l401, l(1)TK401" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0041166 anon-C1 anon-C1 http://flybase.org/reports/FBgn0041166 gene - - - "C1, anon-C1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024627 l(2)k16514 lethal (2) k16514 http://flybase.org/reports/FBgn0024627 - gene - - - "165/14, l(2)k16514" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029644 CG14421 - http://flybase.org/reports/FBgn0029644 protein_coding_gene - - - CG14421 IPR011990:Tetratricopeptide-like helical domain CG14421 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035754 MED4 Mediator complex subunit 4 http://flybase.org/reports/FBgn0035754 protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from direct assay contributes_to RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KN79 inferred from physical interaction with UniProtKB:Q9GYU7 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P91641 inferred from physical interaction with UniProtKB:Q8IH24 inferred from physical interaction with UniProtKB:Q8MSX2 inferred from physical interaction with UniProtKB:Q9VEC1 inferred from physical interaction with UniProtKB:Q9W5P1 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay mediator complex ; GO:0016592 | inferred from sequence or structural similarity core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN001408501 mediator complex ; GO:0016592 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Med4, Trap36, Med4/TRAP36, dp34, p34, dTRAP36, CG8609, MED4, med4" "IPR019258:Mediator complex, subunit Med4" CG8609 11-Aug-17 DroID_v2017_08 "Drer\med4, Drer\zgc:123294" Scer\MED4 Cele\mdt-4 Xtro\med4 Mmus\Med4 Hsap\MED4 "viable,visible" mesothoracic tergum DRSC11014 IK -0.3617063 3.037334515 -0.773862229 0.346684398 2.14059791 1.876380757 FBgn0052208 825-Oak 825-Oak http://flybase.org/reports/FBgn0052208 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32208, 825-Oak" - CG32208 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051386 CR31386 - http://flybase.org/reports/FBgn0051386 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE39877, CG31386, CR31386" - CR31386 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259842 Su(Ste):CR42411 Su(Ste):CR42411 http://flybase.org/reports/FBgn0259842 non_protein_coding_gene - - - "Su(Ste):CR42411, CR42411" - CR42411 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027494 RpS10a Ribosomal protein S10a http://flybase.org/reports/FBgn0027494 FBgn0039534 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement cytoplasmic translation ; GO:0002181 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype translation ; GO:0006412 | inferred by curator from GO:0022627 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000254423 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CG12275, S10, BcDNA:LD32148, RpS10, RpS10a" "IPR005326:Plectin/S10, N-terminal" CG12275 11-Aug-17 DroID_v2017_08 Drer\rps10 "Scer\RPS10B, Scer\RPS10A" Cele\rps-10 Xtro\rps10 "Mmus\Plec, Mmus\Rps10" "Hsap\RPS10, Hsap\RPS10-NUDT3, Hsap\PLEC" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC26061 K -0.166139991 0.711166095 0.501474075 0.440097046 1.307640835 1.605754294 FBgn0005471 l(1)ts639 lethal (1) ts639 http://flybase.org/reports/FBgn0005471 - gene - - - l(1)ts639 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0065297 l(2)SH1996 lethal (2) SH1996 http://flybase.org/reports/FBgn0065297 gene - - - "l(2)SH1996, l(2)SH2 1996" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060374 l(3)S136613 lethal (3) S136613 http://flybase.org/reports/FBgn0060374 gene - - - "1366/13, l(3)S136613" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0015823 T-B7.2 T-B7.2 http://flybase.org/reports/FBgn0015823 - gene - - - T-B7.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260585 2L2870 - http://flybase.org/reports/FBgn0260585 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2870 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0036101 NijA Ninjurin A http://flybase.org/reports/FBgn0036101 protein_coding_gene - tissue regeneration ; GO:0042246 | inferred from electronic annotation with InterPro:IPR007007 cell adhesion ; GO:0007155 | inferred from direct assay inferred from mutant phenotype inferred from genetic interaction with Mmp1 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007007 "CG6449, ninA, NijA" IPR007007:Ninjurin CG6449 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-278o19.1, Drer\ninj2" - - Xtro\ninj1 "Mmus\Ninj1, Mmus\Ninj2" "Hsap\NINJ2, Hsap\NINJ1" "increased cell death,viable,lethal,lethal - all die during pupal stage,fertile" "embryonic/larval lymph gland | larval stage,embryonic/larval hemocyte | larval stage,S2 cell-line" FBgn0046113 GluRIIC Glutamate receptor IIC http://flybase.org/reports/FBgn0046113 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 glutamate receptor activity ; GO:0008066 | non-traceable author statement glutamate-gated calcium ion channel activity ; GO:0022849 | inferred from direct assay ionotropic glutamate receptor activity ; GO:0004970 | inferred by curator from GO:0008328 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity "chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype synaptic transmission, glutamatergic ; GO:0035249 | inferred by curator from GO:0007274,GO:0008328 neuromuscular synaptic transmission ; GO:0007274 | inferred from expression pattern establishment of protein localization ; GO:0045184 | inferred from mutant phenotype regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from direct assay" muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay ionotropic glutamate receptor complex ; GO:0008328 | inferred from mutant phenotype neuromuscular junction ; GO:0031594 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay "GluRIIC, DGluR-IIC, DGluRIIC, CG4226, DGluRIII, CT13021, GluRIII, GluRII-C, GLURIIC, GluR, DmelGluRIIC, glutamate receptor III, GluRIIC/III, GlutRIII, GluR3, GluRC" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG4226 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-183j2.10, Drer\grik4, Drer\LOC100331381, Drer\LOC100334689, Drer\grik1a, Drer\grik5, Drer\si:ch211-251b21.1, Drer\grik1b" - "Cele\glr-4, Cele\glr-8, Cele\glr-5, Cele\glr-6" "Xtro\grik1, Xtro\grik4, Xtro\grik5" "Mmus\Grik2, Mmus\Grik5, Mmus\Grik1, Mmus\Grik4, Mmus\Grik3" "Hsap\GRIK5, Hsap\GRID2, Hsap\GRIK3, Hsap\GRIK4, Hsap\GRIK1, Hsap\GRIK2" "neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,paralytic,viable,lethal" "neuromuscular junction | larval stageast1), with GluRIICUAS.cMa, [-],neuromuscular junction | larval stage, with GluRIIC1/Df(2L)ast1, [-],neuromuscular junction | larval stage, with Df(2L)ast1/GluRIIC2, [-]" FBgn0065675 l(2)SH0676 lethal (2) SH0676 http://flybase.org/reports/FBgn0065675 gene - - - "l(2)SH0676, l(2)SH2 0676" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051523 CG31523 - http://flybase.org/reports/FBgn0051523 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "CG9798, CG31523" IPR002076:ELO family CG31523 11-Aug-17 DroID_v2017_08 "Drer\elovl8b, Drer\elovl1a, Drer\elovl7b, Drer\elovl2, Drer\elovl5, Drer\elovl4a, Drer\elovl1b, Drer\elovl7a, Drer\zgc:101858, Drer\elovl8a, Drer\dhrs7, Drer\elovl4b, Drer\hsd17b8" "Scer\ELO1, Scer\ELO3, Scer\ELO2" "Cele\C06E4.3, Cele\Y47G6A.21, Cele\F28H7.2, Cele\ZK829.1, Cele\Y47G6A.22, Cele\dhs-14, Cele\F25D1.5, Cele\elo-1, Cele\dhs-11, Cele\dhs-25, Cele\F26D2.15" "Xtro\MGC79752, Xtro\elovl1, Xtro\dhrs7, Xtro\elovl5, Xtro\elovl7, Xtro\cbr4, Xtro\elovl2, Xtro\hsd17b8" "Mmus\H2-Ke6, Mmus\Elovl7, Mmus\Elovl2, Mmus\Elovl4, Mmus\Dhrs7, Mmus\Elovl5, Mmus\Elovl1, Mmus\Cbr4" "Hsap\ELOVL2, Hsap\ELOVL4, Hsap\ELOVL5, Hsap\ELOVL1, Hsap\HSD17B8, Hsap\ELOVL7, Hsap\CBR4, Hsap\DHRS7" "partially lethal - majority die,some die during pupal stage" DRSC12337 I 1.895548981 1.058865803 1.029693475 0.25967255 1.285461449 -1.193932646 FBgn0001915 l(2)25Bb lethal (2) 25Bb http://flybase.org/reports/FBgn0001915 - gene - - - "jf11, l(2)jf11, l(2)25Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031401 papi papi http://flybase.org/reports/FBgn0031401 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 protein binding ; GO:0005515 | inferred from physical interaction with me31B inferred from physical interaction with tral inferred from physical interaction with TER94 - P granule ; GO:0043186 | inferred from direct assay "cg7082, CG7082, papi, PAPI, Papi" "IPR002999:Tudor domain, IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG7082 11-Aug-17 DroID_v2017_08 "Drer\akap1a, Drer\si:dkeyp-93d12.1, Drer\tdrd1, Drer\tdrd6, Drer\tdrd7a, Drer\sb:cb829, Drer\akap1b, Drer\si:ch211-189e2.3, Drer\tdrkh, Drer\tdrd5" - "Cele\eri-5, Cele\ekl-1, Cele\F32E10.5, Cele\rsd-6, Cele\tag-250, Cele\akap-1" "Xtro\tdrkh, Xtro\tdrd7" "Mmus\Tdrkh, Mmus\Tdrd6, Mmus\Tdrd12, Mmus\Rnf17, Mmus\Akap1, Mmus\Tdrd1, Mmus\Tdrd7, Mmus\Tdrd5" "Hsap\TDRD15, Hsap\TDRD1, Hsap\TDRKH, Hsap\AKAP1, Hsap\TDRD7, Hsap\TDRD5, Hsap\TDRD6, Hsap\TDRD12, Hsap\TDRD10" viable FBgn0036058 CG6707 - http://flybase.org/reports/FBgn0036058 protein_coding_gene "phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity ; GO:0034597 | inferred from sequence or structural similarity with HGNC:25452" phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from sequence or structural similarity with HGNC:25452 late endosome membrane ; GO:0031902 | inferred from sequence or structural similarity with HGNC:25452 lysosomal membrane ; GO:0005765 | inferred from sequence or structural similarity with HGNC:25452 CG6707 "IPR019178:Phosphatidylinositol 4,5-bisphosphate 4-phosphatase" CG6707 11-Aug-17 DroID_v2017_08 "Drer\tmem55bb, Drer\tmem55a, Drer\tmem55ba" - "Cele\F52E1.9, Cele\Y71H2AM.2" "Xtro\tmem55b, Xtro\tmem55a" "Mmus\Tmem55b, Mmus\Tmem55a" "Hsap\TMEM55B, Hsap\TMEM55A" viable FBgn0037941 CG12594 - http://flybase.org/reports/FBgn0037941 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12594 "IPR001791:Laminin G domain, IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR013320:Concanavalin A-like lectin/glucanase domain" CG12594 11-Aug-17 DroID_v2017_08 "Drer\thbs1b, Drer\thbs2b, Drer\thbs2a, Drer\thbs1a" - - - "Mmus\Thbs1, Mmus\Thbs2" "Hsap\THBS1, Hsap\THBS2" viable DRSC14532 E -0.387410235 1.284140811 1.694064556 0.305104892 0.188497943 -0.79491678 FBgn0020244 y5-5 y5-5 http://flybase.org/reports/FBgn0020244 - gene - - - y5-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037134 CG7407 - http://flybase.org/reports/FBgn0037134 protein_coding_gene - - - "BcDNA:LD29166, CG7407" IPR026622:Matrix-remodeling-associated protein 7 CG7407 11-Aug-17 DroID_v2017_08 - - Cele\C05G5.3 Xtro\mxra7 Mmus\Mxra7 Hsap\MXRA7 viable FBgn0069997 BG01664 BG01664 http://flybase.org/reports/FBgn0069997 gene - - - BG01664 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0022625 Dia7 Diaphorase 7 http://flybase.org/reports/FBgn0022625 - gene - - - "DIA-7, Dia7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038847 CG12278 - http://flybase.org/reports/FBgn0038847 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12278 - CG12278 11-Aug-17 DroID_v2017_08 - - "Cele\Y43F8B.13, Cele\Y43F8B.12, Cele\Y43F8B.25, Cele\Y43F8B.24, Cele\C25F9.9, Cele\C25F9.10, Cele\C25F9.15" - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0003405 si3 ski 3 http://flybase.org/reports/FBgn0003405 - gene - - - "si-3, si3" - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0040361 CG14627 - http://flybase.org/reports/FBgn0040361 protein_coding_gene - - - "EG:BACR42I17.5, CG14627" - CG14627 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041740 l(2)DL1 lethal (2) DL1 http://flybase.org/reports/FBgn0041740 gene - - - l(2)DL1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0039495 CG5909 - http://flybase.org/reports/FBgn0039495 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG5909, c-SP8, SP8" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain" CG5909 11-Aug-17 DroID_v2017_08 "Drer\prss60.1, Drer\f7i, Drer\prss60.3, Drer\prss60.2" - "Cele\try-3, Cele\try-1, Cele\svh-1" - - - viable FBgn0036278 CrzR Corazonin receptor http://flybase.org/reports/FBgn0036278 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from sequence model corazonin receptor activity ; GO:0035237 | inferred from direct assay G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with AkhR corazonin receptor activity ; GO:0035237 | inferred from physical interaction with Crz acetaldehyde metabolic process ; GO:0006117 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with AkhR neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay phospholipase C-activating G-protein coupled receptor signaling pathway ; GO:0007200 | inferred from biological aspect of ancestor with PANTHER:PTN000660491 behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model cellular response to ethanol ; GO:0071361 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay "integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence model inferred by curator from GO:0007186,GO:0035237 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with AkhR" "CG10698, DCR, DGRHRII, anon-WO0170980.197, anon-WO0170980.196, crzR, Crz-R, GRHRII_Dro, CrzR, GRHRII, GRH-RII" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG10698 11-Aug-17 DroID_v2017_08 "Drer\gnrhr2, Drer\gnrhr3, Drer\gnrhr4" - "Cele\gnrr-3, Cele\gnrr-7, Cele\daf-38, Cele\AH9.4, Cele\gnrr-2, Cele\gnrr-6, Cele\npr-21, Cele\gnrr-4, Cele\gnrr-5, Cele\ZC266.1, Cele\gnrr-1" "Xtro\gnrhr2, Xtro\gpr150, Xtro\gnrhr" "Mmus\Gnrhr, Mmus\Gpr150" "Hsap\GNRHR, Hsap\GPR150" "viable,fertile,chemical sensitive" DRSC09781 K 0.770601541 0.314764455 0.25783107 0.190026568 -1.57653305 -0.246825289 FBgn0005222 l(3)ET18 lethal Elaine Tasaka 18 http://flybase.org/reports/FBgn0005222 - gene - - - l(3)ET18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0267897 CR46185 - http://flybase.org/reports/FBgn0267897 pseudogene_attribute - - - "CR46185, CG12717-related" - CR46185 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266464 Nsf2 N-ethylmaleimide-sensitive factor 2 http://flybase.org/reports/FBgn0266464 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with comt" "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with comt synaptic vesicle priming ; GO:0016082 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype SNARE complex disassembly ; GO:0035494 | inferred from sequence or structural similarity with comt neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype" SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with comt "EC3-11, Nsf2, NSF2, lotus, Nsf-2, dNSF2, dnsf2, CG9931, dNSF-2, DmNSF2, dNsf2, NSF-2, dNSF, CG33101" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003338:CDC48, N-terminal subdomain, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR004201:CDC48, domain 2, IPR009010:Aspartate decarboxylase-like domain, IPR029067:CDC48 domain 2-like" CG33101 11-Aug-17 DroID_v2017_08 "Drer\nsfa, Drer\nsfb" Scer\SEC18 Cele\nsf-1 Xtro\nsf Mmus\Nsf Hsap\NSF " embryonic stage , larval stage , embryonic stage | stage 5,6 , embryonic stage | stage 8-10 , embryonic stage | stage 8-11 , embryonic stage && larval stage && adult stage , embryonic stage | stage >=14 " " embryonic/larval midgut

, dorsal mesothoracic disc

,

ubiquitous , posterior midgut proper primordium

, embryonic/larval hindgut

, mesoderm

, ectoderm

, anterior midgut proper primordium

, eye-antennal disc

, embryonic/larval salivary gland | restricted

, imaginal disc

, ring gland

, embryonic central nervous system

, ventral thoracic disc

" FBgn0267876 CR46164 - http://flybase.org/reports/FBgn0267876 pseudogene_attribute - - - "CR46164, CG12717-related" - CR46164 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019767 l(1)54B1 lethal (1) 54B1 http://flybase.org/reports/FBgn0019767 - gene - - - l(1)54B1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053207 pxb pxb http://flybase.org/reports/FBgn0053207 protein_coding_gene - behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype negative regulation of hemocyte proliferation ; GO:0035207 | inferred from genetic interaction with hop olfactory learning ; GO:0008355 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - "CG14873, CG33207, CG14874, BcDNA:RE16319, pxb, Pxb, CG33207/Pxb" - CG33207 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,chemical sensitive,behavior defective,recessive,viable,fertile" "macrochaeta,microchaeta & tarsal segment 5Dll-em212,microchaeta & tarsal segment 5ptc-559.1,anterior scutellar bristle,posterior scutellar bristle,microchaeta & tarsal segment 5hh-Gal4" DRSC14996 IEK 2.955291433 0.789206155 1.952390759 -0.3779634 -2.690729855 -0.708003824 FBgn0043486 l(2)05271b lethal (2) 05271b http://flybase.org/reports/FBgn0043486 gene - - - "l(2)05271, l(2)05271b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible" "leg,metathoracic tibia,metathoracic metatarsus" FBgn0011296 l(2)efl lethal (2) essential for life http://flybase.org/reports/FBgn0011296 FBgn0011779 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model sarcomere organization ; GO:0045214 | inferred from mutant phenotype protein refolding ; GO:0042026 | inferred from direct assay response to heat ; GO:0009408 | inferred from direct assay regulation of translational initiation by eIF2 alpha phosphorylation ; GO:0010998 | inferred from mutant phenotype Z disc ; GO:0030018 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "Dmel19.8, l(2)Efl, l(2)59Fa, l(2)13-1, el(2)13-1, CG4533, l(2)efl, L(2)efl, Cryab, CryAB, L(2)EFL" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4533 11-Aug-17 DroID_v2017_08 "Drer\cryaba, Drer\cryabb, Drer\hspb8, Drer\hspb11, Drer\hspb12, Drer\si:dkey-1k23.3, Drer\hspb9, Drer\hspb6, Drer\hspb7, Drer\hspb15, Drer\hspb3, Drer\hspb2, Drer\cryaa, Drer\hspb1" - "Cele\hsp-16.1, Cele\F08H9.3, Cele\hsp-12.2, Cele\hsp-16.49, Cele\F08H9.4, Cele\hsp-16.41, Cele\hsp-12.1, Cele\hsp-12.3, Cele\Y55F3BR.6, Cele\hsp-16.11, Cele\hsp-12.6, Cele\sip-1, Cele\hsp-16.2, Cele\hsp-25, Cele\hsp-43, Cele\ZK1128.7, Cele\hsp-17, Cele\hsp-16.48" "Xtro\cryab, Xtro\hspb8, Xtro\cryaa, Xtro\hspb1, Xtro\hsp30d, Xtro\hspb6, Xtro\hspb2, Xtro\uqcrh, Xtro\hspb3" "Mmus\Hspb2, Mmus\Cryaa, Mmus\Hspb8, Mmus\Hspb1, Mmus\Hspb6, Mmus\Hspb3, Mmus\Cryab, Mmus\Hspb7, Mmus\Hspb9" "Hsap\HSPB2, Hsap\CRYAA, Hsap\HSPB1, Hsap\CRYAB, Hsap\HSPB6, Hsap\HSPB9, Hsap\HSPB8, Hsap\HSPB7, Hsap\LOC102724652, Hsap\HSPB3" " embryonic stage , embryonic stage -- adult stage " "long lived,viable" FBgn0013513 l(1)14Ai lethal (1) 14Ai http://flybase.org/reports/FBgn0013513 - gene - - - "XII, mn4, l(1)XII, l(1)13Fl, l(1)14Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083120 Uhg8 Uhg8 http://flybase.org/reports/FBgn0083120 non_protein_coding_gene - - - "Uhg8, dUhg8, CR42454" - CR42454 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003064 anon-Pen79B anon-Pen79B http://flybase.org/reports/FBgn0003064 - gene - - - "GCR-21, pen79B, Pen79B, GCR21, anon-Pen79B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265046 CG44163 - http://flybase.org/reports/FBgn0265046 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44163 - CG44163 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051163 SKIP Shal K[+] channel interacting protein http://flybase.org/reports/FBgn0051163 protein_coding_gene - sensory perception of smell ; GO:0007608 | inferred from mutant phenotype - "CG7087, CG7086, CG5736, CG13864, CG13863, CG31163, SKIP" "IPR001452:SH3 domain, IPR001660:Sterile alpha motif domain, IPR011511:Variant SH3 domain, IPR013761:Sterile alpha motif/pointed domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG31163 11-Aug-17 DroID_v2017_08 "Drer\samsn1b, Drer\inppl1a, Drer\sash3, Drer\samsn1a, Drer\sash1a, Drer\sash1b" - - "Xtro\samsn1, Xtro\wwp2, Xtro\sash3, Xtro\sash1" "Mmus\Samsn1, Mmus\Inppl1, Mmus\Caskin2, Mmus\Sash1, Mmus\Samd5, Mmus\Sash3" "Hsap\SASH1, Hsap\INPPL1, Hsap\SAMD5, Hsap\SAMSN1, Hsap\CASKIN2, Hsap\SASH3" "viable,fertile,smell perception defective" DRSC15864 I -1.750174428 0.789425996 -0.062565163 -0.162429267 -0.027969354 0.783927083 FBgn0032858 CG10949 - http://flybase.org/reports/FBgn0032858 protein_coding_gene - - - "FBgn0032858, 38C.46, CG10949, CC34" IPR006578:MADF domain CG10949 11-Aug-17 DroID_v2017_08 "Drer\LOC100330838, Drer\si:ch211-207i20.3, Drer\zgc:152938" - "Cele\madf-10, Cele\madf-5, Cele\madf-9, Cele\madf-8, Cele\madf-3, Cele\madf-4, Cele\madf-2" - - - viable FBgn0260643 CG42535 - http://flybase.org/reports/FBgn0260643 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42535 IPR031720:Protein of unknown function DUF4728 CG42535 11-Aug-17 DroID_v2017_08 - - Cele\sre-55 - - - FBgn0065948 l(2)SH0090 lethal (2) SH0090 http://flybase.org/reports/FBgn0065948 gene - - - "l(2)SH0090, l(2)SH2 0090" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032139 CG13116 - http://flybase.org/reports/FBgn0032139 protein_coding_gene - - - CG13116 - CG13116 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" DRSC21945 IE 0.619769892 -1.815696396 -0.848566099 -2.862823447 0.583884643 -0.097195337 FBgn0082623 S(CycE[JP])42S12 S(CycE[JP])42S12 http://flybase.org/reports/FBgn0082623 gene - - - "42S12, S(CycE[JP])42S12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065358 l(2)SH1751 lethal (2) SH1751 http://flybase.org/reports/FBgn0065358 gene - - - "l(2)SH1751, l(2)SH2 1751" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025830 IntS8 Integrator 8 http://flybase.org/reports/FBgn0025830 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA 3'-end processing ; GO:0034472 | inferred from direct assay snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:26048 integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:26048 "EG:EG0003.5, IntS8, CG5859, Int8" IPR011990:Tetratricopeptide-like helical domain CG5859 11-Aug-17 DroID_v2017_08 Drer\ints8 - Cele\Y48G10A.4 Xtro\ints8 Mmus\Ints8 Hsap\INTS8 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC07417 I 0.250661945 -1.588239826 0.496869529 -0.036288503 -1.254237386 -0.4438577 FBgn0025727 tra::tra2 tra::tra2 http://flybase.org/reports/FBgn0025727 - engineered_fusion_gene - - - "TRA-2/TRA, tra::tra2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010950 l(3)j00015 lethal (3) j00015 http://flybase.org/reports/FBgn0010950 - gene - - - l(3)j00015 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035594 CG4597 - http://flybase.org/reports/FBgn0035594 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4597 IPR010512:Protein of unknown function DUF1091 CG4597 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0264483 CR43891 - http://flybase.org/reports/FBgn0264483 non_protein_coding_gene - - - CR43891 - CR43891 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065089 snmRNA:637 small non-messenger RNA 637 http://flybase.org/reports/FBgn0065089 non_protein_coding_gene - - - "Dm-637, snmRNA:637" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266473 walnut - http://flybase.org/reports/FBgn0266473 gene - - - walnut - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069237 gl(1)82-33 gl(1)82-33 http://flybase.org/reports/FBgn0069237 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(1)82-33 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryo,germline clone,maternal effect,posterior" FBgn0262120 l(2)L10 - http://flybase.org/reports/FBgn0262120 gene - - - l(2)L10 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263042 CG43337 - http://flybase.org/reports/FBgn0263042 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD03580, CG32345, CG43337" - CG43337 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034271 Vps54L Vacuolar protein sorting 54L http://flybase.org/reports/FBgn0034271 protein_coding_gene molecular_function ; GO:0003674 | no biological data available endocytic recycling ; GO:0032456 | inferred from sequence or structural similarity with UniProtKB:Q96JG6 endosome ; GO:0005768 | inferred from direct assay GARP complex ; GO:0000938 | colocalizes_with inferred from direct assay "CG4996, Vps54L" "IPR019514:Protein of unknown function DUF2451, C-terminal, IPR019515:Vacuolar protein sorting-associated protein 54, N-terminal" CG4996 11-Aug-17 DroID_v2017_08 Drer\si:ch211-287b5.1 - Cele\vps-50 Xtro\vps50 Mmus\Vps50 Hsap\VPS50 viable FBgn0260074 2L3948 - http://flybase.org/reports/FBgn0260074 gene - - - 2L3948 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0001013 fs(3)A4 female sterile (3) A4 http://flybase.org/reports/FBgn0001013 - gene - - - fs(3)A4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0027989 l(3)S127416 lethal (3) S127416 http://flybase.org/reports/FBgn0027989 gene - - - "1274/16, l(3)S127416" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264402 FCG-E - http://flybase.org/reports/FBgn0264402 gene - - - FCG-E - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0034082 CG10734 - http://flybase.org/reports/FBgn0034082 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10734 - CG10734 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0036204 Tim13 Tim13 http://flybase.org/reports/FBgn0036204 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000451188 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProt:Q9Y5L4 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProt:Q9Y5L4 protein import into mitochondrial inner membrane ; GO:0045039 | inferred from biological aspect of ancestor with PANTHER:PTN000451188 chaperone-mediated protein transport ; GO:0072321 | inferred from biological aspect of ancestor with PANTHER:PTN000451188 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProt:Q9Y5L4 mitochondrial intermembrane space protein transporter complex ; GO:0042719 | inferred from biological aspect of ancestor with PANTHER:PTN000451188 "CG11611, Tim13" IPR004217:Tim10/DDP family zinc finger CG11611 11-Aug-17 DroID_v2017_08 Drer\timm13 Scer\TIM13 Cele\tin-13 Xtro\timm13 Mmus\Timm13 Hsap\TIMM13 viable FBgn0051001 CG31001 - http://flybase.org/reports/FBgn0051001 protein_coding_gene - - - CG31001 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060891 l(3)S044623b lethal (3) S044623b http://flybase.org/reports/FBgn0060891 gene - - - "0446/23, l(3)S044623b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033464 CG1441 - http://flybase.org/reports/FBgn0033464 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - CG1441 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG1441 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97m3.1, Drer\far1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR2, Hsap\FAR1" "viable,fertile" DRSC06448 K 0.136227607 0.358566588 0.754044127 0.33330933 -0.402207443 -1.607116479 FBgn0260045 33R11 - http://flybase.org/reports/FBgn0260045 gene - - - 33R11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0030400 CG11138 - http://flybase.org/reports/FBgn0030400 protein_coding_gene - - nuclear periphery ; GO:0034399 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay polytene chromosome ; GO:0005700 | colocalizes_with inferred from direct assay "RE18684, EP(X)1313, CG1855, BEST:RE18684, BcDNA:RE48052, CG11138" "IPR022750:Interferon regulatory factor 2-binding protein 1 & 2, zinc finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11138 11-Aug-17 DroID_v2017_08 "Drer\irf2bp1, Drer\irf2bp2a, Drer\irf2bpl, Drer\irf2bp2b" - Cele\tag-260 "Xtro\irf2bp2, Xtro\irf2bpl" "Mmus\Irf2bp1, Mmus\Irf2bpl, Mmus\Irf2bp2" "Hsap\IRF2BP1, Hsap\IRF2BP2, Hsap\IRF2BPL" viable FBgn0033960 CG10151 - http://flybase.org/reports/FBgn0033960 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10151 IPR015943:WD40/YVTN repeat-like-containing domain CG10151 11-Aug-17 DroID_v2017_08 Drer\msantd1 - - - "Mmus\Msantd2, Mmus\Zscan29, Mmus\Msantd1, Mmus\Utf1" "Hsap\MSANTD2, Hsap\ZSCAN29, Hsap\UTF1, Hsap\MSANTD1" viable FBgn0058381 CG40381 - http://flybase.org/reports/FBgn0058381 protein_coding_gene - - - CG40381 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061171 l(1)11Ba lethal (1) 11Ba http://flybase.org/reports/FBgn0061171 gene - - - l(1)11Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265667 CR44474 - http://flybase.org/reports/FBgn0265667 non_protein_coding_gene - - - CR44474 - CR44474 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032898 CR9337 - http://flybase.org/reports/FBgn0032898 pseudogene_attribute - - - "CR9337, CG9337, cg9337, BcDNA:GH05725" - CR9337 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000202 bo bordeaux http://flybase.org/reports/FBgn0000202 - gene - - - bo - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" "Malpighian tubule,pigment cell" FBgn0040988 CG15146 - http://flybase.org/reports/FBgn0040988 protein_coding_gene - - - CG15146 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028561 sut3 sugar transporter 3 http://flybase.org/reports/FBgn0028561 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from electronic annotation with InterPro:IPR003663 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003663, InterPro:IPR005828 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 "CG17976, sut3" "IPR003663:Sugar/inositol transporter, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG17976 11-Aug-17 DroID_v2017_08 "Drer\slc2a3b, Drer\slc2a1b, Drer\slc2a12, Drer\slc2a1a, Drer\slc2a11a, Drer\LOC100334818, Drer\slc2a3a, Drer\slc2a15a, Drer\slc2a6, Drer\LOC101882338, Drer\slc2a13b, Drer\slc2a11l, Drer\slc2a10, Drer\slc2a11b, Drer\slc2a8, Drer\slc2a9l1, Drer\slc2a2, Drer\slc2a15b" "Scer\ENB1, Scer\VBA2, Scer\RGT2, Scer\GAL2, Scer\HXT8, Scer\MPH2, Scer\HXT1, Scer\VBA3, Scer\HXT3, Scer\SGE1, Scer\YDL199C, Scer\HXT5, Scer\GEX2, Scer\ATR1, Scer\HXT7, Scer\HXT9, Scer\HXT11, Scer\AZR1, Scer\HXT2, Scer\VPS73, Scer\MPH3, Scer\YFL040W, Scer\VBA5, Scer\HXT10, Scer\HXT16, Scer\HXT13, Scer\HXT17, Scer\YMR279C, Scer\SNF3, Scer\HXT14, Scer\ITR1, Scer\MAL11, Scer\YDR387C, Scer\HXT6, Scer\ITR2, Scer\HXT4, Scer\MAL31, Scer\VBA4, Scer\HXT15, Scer\YBR241C, Scer\GEX1, Scer\VBA1, Scer\STL1" "Cele\C35A11.4, Cele\fgt-1, Cele\K09C4.5, Cele\F53H8.3, Cele\F13B12.2, Cele\K09C4.4, Cele\R09B5.11, Cele\Y39B6A.41, Cele\K08F9.1, Cele\C03B1.13, Cele\K09C4.1, Cele\F11D5.5, Cele\Y37A1A.3, Cele\F14E5.1, Cele\Y39E4B.5, Cele\F48E3.2, Cele\ZK829.9, Cele\Y61A9LA.1, Cele\F11D5.7, Cele\slcf-2, Cele\K08H10.6" "Xtro\LOC100496725, Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a9, Xtro\slc2a6, Xtro\slc2a12, Xtro\slc2a11, Xtro\slc2a7, Xtro\slc2a5" "Mmus\Slc2a5, Mmus\Slc2a1, Mmus\Slc2a8, Mmus\Slc2a9, Mmus\Slc2a2, Mmus\Slc2a6, Mmus\Slc2a12, Mmus\Slc2a3, Mmus\Slc2a13, Mmus\Slc2a4, Mmus\Slc2a10, Mmus\Slc2a7" "Hsap\SLC2A5, Hsap\SLC2A12, Hsap\SLC2A8, Hsap\SLC2A4, Hsap\SLC2A2, Hsap\SLC2A13, Hsap\SLC2A9, Hsap\SLC2A14, Hsap\SLC2A6, Hsap\SLC2A1, Hsap\SLC2A11, Hsap\MIF, Hsap\SLC2A3, Hsap\SLC2A7, Hsap\SLC2A10" viable FBgn0032467 CG9934 - http://flybase.org/reports/FBgn0032467 protein_coding_gene ubiquitin-ubiquitin ligase activity ; GO:0034450 | inferred from sequence or structural similarity with SGD:S000002349 ubiquitin-ubiquitin ligase activity ; GO:0034450 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000002349 ubiquitin ligase complex ; GO:0000151 | inferred from electronic annotation with InterPro:IPR019474 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 "CG9934, UBE4B, dUfd2, CG 9934, UFD2b, E4 B, ufd2, Ube4b" "IPR003613:U box domain, IPR019474:Ubiquitin conjugation factor E4, core, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9934 11-Aug-17 DroID_v2017_08 "Drer\ube4b, Drer\ube4a, Drer\ubox5" Scer\UFD2 Cele\ufd-2 "Xtro\ube4a, Xtro\ubox5, Xtro\ube4b" "Mmus\Ube4b, Mmus\Ubox5, Mmus\Ube4a" "Hsap\UBE4B, Hsap\UBE4A, Hsap\UBOX5" viable FBgn0266135 c282 - http://flybase.org/reports/FBgn0266135 gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - c282 - - 11-Aug-17 DroID_v2017_08 - - - - - - gravitaxis defective FBgn0033449 CG1663 - http://flybase.org/reports/FBgn0033449 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG1663 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG1663 11-Aug-17 DroID_v2017_08 "Drer\rest, Drer\zbtb16a, Drer\LOC100535113, Drer\zbtb16b, Drer\znf1079, Drer\LOC100537891, Drer\znf148, Drer\znf1078, Drer\si:ch211-253b8.2, Drer\si:dkey-220a11.7, Drer\znf1059, Drer\znf653, Drer\znf1068, Drer\zbtb32" Scer\CRZ1 Cele\pag-3 - "Mmus\Zfp148, Mmus\Zfp691, Mmus\Zbtb16, Mmus\Zbtb32" "Hsap\ZBTB32, Hsap\ZNF691, Hsap\ZNF148, Hsap\ZBTB16" viable FBgn0002078 l(2)49Fg lethal (2) 49Fg http://flybase.org/reports/FBgn0002078 - gene - - - "vr11, vr-11, l(2)vr11, l(2)49Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,non-suppressor of variegation,dominant" FBgn0041231 Gr68a Gustatory receptor 68a http://flybase.org/reports/FBgn0041231 protein_coding_gene taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 "sensory perception of taste ; GO:0050909 | non-traceable author statement male courtship behavior, tapping to detect pheromone ; GO:0016544 | inferred from mutant phenotype sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement response to pheromone ; GO:0019236 | inferred from mutant phenotype response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr68D1, 68D.1, GR68D.1, CG7303, Gr68a, GR68a" IPR013604:7TM chemoreceptor CG7303 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0266049 CR44814 - http://flybase.org/reports/FBgn0266049 non_protein_coding_gene - - - CR44814 - CR44814 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058162 CG40162 - http://flybase.org/reports/FBgn0058162 protein_coding_gene - - - CG40162 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20863 K 0.18125047 0.275146943 0.043751431 0.291621965 -1.712952325 -0.521284529 FBgn0043889 l(3)C416 lethal (3) C416 http://flybase.org/reports/FBgn0043889 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available l(3)C416 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259862 Su(Ste):CR42431 Su(Ste):CR42431 http://flybase.org/reports/FBgn0259862 non_protein_coding_gene - - - "Su(Ste):CR42431, CR42431" - CR42431 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260453 CG17140 - http://flybase.org/reports/FBgn0260453 protein_coding_gene channel activity ; GO:0015267 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR027246 mitochondrial outer membrane ; GO:0005741 | inferred from electronic annotation with InterPro:IPR027246 "CG31722, CG17140, CG31722-B" IPR027246:Eukaryotic porin/Tom40 CG17140 11-Aug-17 DroID_v2017_08 "Drer\vdac2, Drer\vdac3, Drer\zgc:56235, Drer\vdac1, Drer\LOC101886830" "Scer\POR2, Scer\POR1" Cele\vdac-1 "Xtro\vdac2, Xtro\vdac1, Xtro\vdac3" "Mmus\Vdac1, Mmus\Vdac2, Mmus\Vdac3" "Hsap\VDAC2, Hsap\VDAC3, Hsap\VDAC1" FBgn0034553 CG9993 - http://flybase.org/reports/FBgn0034553 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG9993 "IPR000873:AMP-dependent synthetase/ligase, IPR025110:AMP-binding enzyme C-terminal domain" CG9993 11-Aug-17 DroID_v2017_08 "Drer\acsf3, Drer\acsbg1" Scer\PCS60 "Cele\acs-14, Cele\acs-11, Cele\acs-10, Cele\C25G6.3, Cele\acs-6, Cele\acs-7, Cele\mec-18, Cele\C32E8.6, Cele\acs-9" Xtro\acsf3 "Mmus\Acsbg1, Mmus\Acsm2, Mmus\Acsf3" "Hsap\ACSBG1, Hsap\ACSM2A, Hsap\ACSF3" viable FBgn0034274 CG10931 - http://flybase.org/reports/FBgn0034274 protein_coding_gene histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from sequence or structural similarity with HGNC:12757 histone H3 acetylation ; GO:0043966 | inferred from sequence or structural similarity with HGNC:12757 histone H3-K4 methylation ; GO:0051568 | inferred from sequence or structural similarity with HGNC:12757 histone methyltransferase complex ; GO:0035097 | inferred from sequence or structural similarity with HGNC:12757 histone acetyltransferase complex ; GO:0000123 | inferred from sequence or structural similarity with HGNC:12757 CG10931 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG10931 11-Aug-17 DroID_v2017_08 "Drer\wdr90, Drer\cfap52, Drer\wsb2, Drer\ambra1a, Drer\wdr5" "Scer\TUP1, Scer\YMR102C, Scer\PRP4, Scer\SWD3" "Cele\wdr-5.3, Cele\wdr-5.1, Cele\wdr-5.2" "Xtro\wdr5, Xtro\wdr90, Xtro\ambra1" "Mmus\Cfap52, Mmus\Wdr5b, Mmus\Wdr90, Mmus\Wdr95, Mmus\Wdr5, Mmus\Wsb2, Mmus\Nwd1, Mmus\Wsb1, Mmus\Ambra1, Mmus\Dtl, Mmus\Wdr38" "Hsap\CFAP52, Hsap\WDR88, Hsap\DTL, Hsap\WDR5, Hsap\WSB2, Hsap\WDR38, Hsap\WDR5B, Hsap\WDR90" FBgn0028058 l(3)S094003 lethal (3) S094003 http://flybase.org/reports/FBgn0028058 gene - - - "0940/03, l(3)S094003" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024537 l(3)L1459 lethal (3) L1459 http://flybase.org/reports/FBgn0024537 - gene - - - l(3)L1459 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037722 CG8319 - http://flybase.org/reports/FBgn0037722 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG8319 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8319 11-Aug-17 DroID_v2017_08 "Drer\znf1070, Drer\znf1073, Drer\znf1069, Drer\LOC101883936, Drer\zgc:171673, Drer\LOC100536900, Drer\zgc:101562, Drer\LOC103910931, Drer\znf410, Drer\prdm5, Drer\LOC100329258, Drer\LOC103911751, Drer\si:ch73-144d13.5, Drer\zgc:173705, Drer\si:ch211-241b2.4, Drer\LOC100332787, Drer\zgc:174224, Drer\si:dkey-237m9.1, Drer\LOC100537066" Scer\PZF1 "Cele\klu-2, Cele\odd-2, Cele\ces-1, Cele\lsy-2, Cele\M03D4.4, Cele\ztf-14, Cele\B0310.2, Cele\eor-1, Cele\zag-1, Cele\che-1, Cele\Y55F3AM.14" - "Mmus\Zfp358, Mmus\Zfp40, Mmus\Zfp410, Mmus\Zfp189, Mmus\Zfp575" "Hsap\ZNF410, Hsap\ZNF560, Hsap\ZNF575, Hsap\ZNF121, Hsap\ZNF850, Hsap\ZNF521, Hsap\ZSCAN32, Hsap\ZNF358, Hsap\PRDM5, Hsap\ZNF70, Hsap\ZNF707" viable FBgn0030983 CG15882 - http://flybase.org/reports/FBgn0030983 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15882 - CG15882 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0084232 W54 W54 http://flybase.org/reports/FBgn0084232 gene - - - W54 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0004704 l(2)56Ff lethal (2) 56Ff http://flybase.org/reports/FBgn0004704 - gene - - - "l(2)56F, l(2)56Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034899 CG13560 - http://flybase.org/reports/FBgn0034899 protein_coding_gene - - - CG13560 - CG13560 11-Aug-17 DroID_v2017_08 Drer\si:ch73-359m17.9 - - - - - DRSC27479 K 0.578180783 1.142226968 0.556637907 0.873109496 1.5586713 0.601167478 FBgn0259851 Su(Ste):CR42420 Su(Ste):CR42420 http://flybase.org/reports/FBgn0259851 non_protein_coding_gene - - - "Su(Ste):CR42420, CR42420" - CR42420 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041574 CG14599 - http://flybase.org/reports/FBgn0041574 protein_coding_gene - - - CG14599 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267292 CR45728 - http://flybase.org/reports/FBgn0267292 non_protein_coding_gene - - - CR45728 - CR45728 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041748 l(1)em1 lethal (1) em1 http://flybase.org/reports/FBgn0041748 gene - - - l(1)em1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053836 His3:CG33836 His3:CG33836 http://flybase.org/reports/FBgn0053836 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33836, His3:CG33836" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33836 11-Aug-17 DroID_v2017_08 "Drer\hist2h3c, Drer\h3f3c, Drer\zgc:173552, Drer\h3f3b.1, Drer\h3f3a, Drer\LOC108190747, Drer\si:ch73-36p18.2, Drer\cenpa, Drer\zgc:113983, Drer\hist2h3ca1, Drer\zgc:113984, Drer\h3f3d, Drer\LOC108190746, Drer\si:ch1073-429i10.3" "Scer\HHT1, Scer\HHT2, Scer\CSE4" "Cele\his-13, Cele\his-69, Cele\his-63, Cele\his-72, Cele\his-74, Cele\his-59, Cele\his-25, Cele\his-55, Cele\his-49, Cele\his-17, Cele\his-71, Cele\his-27, Cele\his-6, Cele\his-9, Cele\his-42, Cele\his-2, Cele\his-45, Cele\his-32" "Xtro\hist2h3d, Xtro\LOC101732670, Xtro\h3f3b, Xtro\cenpa" "Mmus\Hist1h3a, Mmus\Hist1h3g, Mmus\Hist1h3d, Mmus\Hist1h3e, Mmus\H3f3b, Mmus\Cenpa, Mmus\Hist2h3c1, Mmus\Hist2h3b, Mmus\H3f3a, Mmus\Hist1h3f, Mmus\Hist1h3h, Mmus\Hist1h3b, Mmus\Hist1h3i, Mmus\Hist1h3c, Mmus\Hist2h3c2" "Hsap\H3F3B, Hsap\HIST1H3E, Hsap\HIST1H3D, Hsap\HIST1H3C, Hsap\HIST1H3G, Hsap\HIST1H3H, Hsap\HIST1H3F, Hsap\HIST1H3B, Hsap\HIST3H3, Hsap\HIST1H3A, Hsap\HIST2H3C, Hsap\CENPA, Hsap\H3F3C, Hsap\HIST2H3D, Hsap\H3F3A, Hsap\HIST2H3A, Hsap\HIST1H3I, Hsap\HIST1H3J" FBgn0037810 sle slender lobes http://flybase.org/reports/FBgn0037810 protein_coding_gene molecular_function ; GO:0003674 | no biological data available rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000529705 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000529705 nucleolus organization ; GO:0007000 | inferred from mutant phenotype "spindle ; GO:0005819 | inferred from direct assay preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000529705 microtubule associated complex ; GO:0005875 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay" "CG12819, sle, CG12819-PA, FBtr0082231, SLE, Sle" - CG12819 11-Aug-17 DroID_v2017_08 "Drer\rpgrb, Drer\rpgra, Drer\mdn1" "Scer\MRC1, Scer\MDN1" "Cele\D1086.9, Cele\Y6B3B.1, Cele\F55F10.1" - "Mmus\Tchhl1, Mmus\Nes, Mmus\Samd15, Mmus\Mdn1" "Hsap\MDN1, Hsap\SAMD15" "viable,sterile,recessive,developmental rate defective,neuroanatomy defective" "mushroom body alpha-lobe,mushroom body beta-lobe,neuroblast,nucleolus,adult mushroom body,mushroom body,alpha'/beta' Kenyon cell,alpha/beta Kenyon cell,gamma Kenyon cell" FBgn0266254 CR44949 - http://flybase.org/reports/FBgn0266254 non_protein_coding_gene - - - "CR44949, lincRNA.854" - CR44949 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031232 CG11617 - http://flybase.org/reports/FBgn0031232 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR008422, InterPro:IPR009057" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR008422 neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "CG11617, Mkx" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR008422:Homeobox KN domain" CG11617 11-Aug-17 DroID_v2017_08 "Drer\irx6a, Drer\mkxa, Drer\mkxb, Drer\irx2a, Drer\irx4b, Drer\irx1a, Drer\irx5b, Drer\pknox2, Drer\irx3b, Drer\irx4a, Drer\pknox1.1, Drer\meis2b, Drer\irx3a, Drer\meis1a, Drer\meis3, Drer\pknox1.2, Drer\irx5a, Drer\irx7, Drer\meis2a, Drer\irx1b, Drer\tgif1" "Scer\HMLALPHA2, Scer\HMRA2, Scer\TOS8, Scer\MATALPHA2, Scer\CUP9" Cele\irx-1 "Xtro\mkx, Xtro\irx3, Xtro\tgif1, Xtro\meis1, Xtro\pknox2, Xtro\irx5, Xtro\irx1, Xtro\meis2, Xtro\irx4, Xtro\irx2, Xtro\meis3, Xtro\tgif2" "Mmus\Tgif2lx2, Mmus\Mkx, Mmus\Pknox1, Mmus\Tgif2lx1, Mmus\Tgif1, Mmus\Tgif2, Mmus\Irx6, Mmus\Pknox2, Mmus\Meis2, Mmus\Irx2, Mmus\Irx1, Mmus\Meis1, Mmus\Irx4, Mmus\Irx3, Mmus\Irx5, Mmus\Meis3" "Hsap\MEIS1, Hsap\TGIF2LY, Hsap\IRX2, Hsap\TGIF2LX, Hsap\MKX, Hsap\PKNOX1, Hsap\TGIF1, Hsap\TGIF2-C20orf24, Hsap\IRX6, Hsap\IRX3, Hsap\IRX5, Hsap\TGIF2, Hsap\IRX4, Hsap\MEIS2, Hsap\IRX1, Hsap\PKNOX2" "viable,fertile,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC00321 K 0.038619912 -0.131914706 -0.32808887 0.276053515 0.284158396 -1.664058312 FBgn0002784 Mosaic Mosaic http://flybase.org/reports/FBgn0002784 - gene - - - "Mosaic, Mos" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "dorsocentral bristle,scutellar bristle,adult thorax & macrochaeta" FBgn0035971 CG4477 - http://flybase.org/reports/FBgn0035971 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - CG4477 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG4477 11-Aug-17 DroID_v2017_08 Drer\st14b - - - - - "viable,visible" trichogen cell FBgn0267736 CR46067 - http://flybase.org/reports/FBgn0267736 non_protein_coding_gene - - - "CR46067, Mgn99916" - CR46067 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011453 l(3)neo9 lethal (3) neo9 http://flybase.org/reports/FBgn0011453 - gene - - - l(3)neo9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033601 Cpr47Ed Cuticular protein 47Ed http://flybase.org/reports/FBgn0033601 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr47Ed, CG9076, DmelCpr47Ed" IPR000618:Insect cuticle protein CG9076 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0065609 l(2)SH0840 lethal (2) SH0840 http://flybase.org/reports/FBgn0065609 gene - - - "l(2)SH0840, l(2)SH2 0840" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262839 CG43203 - http://flybase.org/reports/FBgn0262839 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43203, CG42793, noncoding_17732" - CG43203 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040683 CG14663 - http://flybase.org/reports/FBgn0040683 protein_coding_gene - - - CG14663 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264496 CR43898 - http://flybase.org/reports/FBgn0264496 non_protein_coding_gene - - - CR43898 - CR43898 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030384 CG2577 - http://flybase.org/reports/FBgn0030384 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966" regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 neurogenesis ; GO:0022008 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from biological aspect of ancestor with PANTHER:PTN000225967 Wnt signaling pathway ; GO:0016055 | inferred from biological aspect of ancestor with PANTHER:PTN000225967 peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein phosphorylation ; GO:0006468 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay CG2577 "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG2577 11-Aug-17 DroID_v2017_08 Drer\csnk1a1 "Scer\HRR25, Scer\YCK3, Scer\YCK2, Scer\YCK1" "Cele\T05C12.1, Cele\K09E4.1, Cele\spe-6, Cele\kin-19, Cele\Y111B2A.27, Cele\F53C3.1" Xtro\csnk1a1 "Mmus\Csnk1e, Mmus\Csnk1a1" "Hsap\CSNK1A1, Hsap\CSNK1A1L" "viable,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0003378 Sgs8 Salivary gland secretion 8 http://flybase.org/reports/FBgn0003378 - protein_coding_gene - - - "sgs8, Sgs, Sgs-8, sgs-8, 68C GII, CG6132, Sgs8" - CG6132 11-Aug-17 DroID_v2017_08 - - - - - - larval stage | third instar salivary gland

"lethal,viable" embryonic/larval brain FBgn0029686 CG2941 - http://flybase.org/reports/FBgn0029686 protein_coding_gene - - - CG2941 - CG2941 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250839 CG2016 - http://flybase.org/reports/FBgn0250839 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CG2016, anon-SAGE:Wang-083" IPR010562:Haemolymph juvenile hormone binding CG2016 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260259 GSd329 - http://flybase.org/reports/FBgn0260259 gene - - - GSd329 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259655 B0929 - http://flybase.org/reports/FBgn0259655 gene - - - B0929 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,submarginal cell,wing cell,wing" FBgn0085603 CG41297 - http://flybase.org/reports/FBgn0085603 protein_coding_gene - - - CG41297 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014281 l(3)3h lethal (3) 3h http://flybase.org/reports/FBgn0014281 - gene - - - "l(3L)3h, l(3)3h" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265155 CR44224 - http://flybase.org/reports/FBgn0265155 non_protein_coding_gene - - - CR44224 - CR44224 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262181 mir-972 mir-972 stem loop http://flybase.org/reports/FBgn0262181 miRNA_gene - - - "mir-972, miR-972, CR42888, dme-mir-972" - CR42888 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259170 alpha-Man-Ia alpha-Mannosidase class I a http://flybase.org/reports/FBgn0259170 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001382 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from direct assay" N-glycan processing ; GO:0006491 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype response to anesthetic ; GO:0072347 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000201534 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 "CG42275, alpha-Man-I, Man'ase, mas-1, CG18799, alpha-Man-l, DM-GI, MA12, MAN-1, CG17809, CG32684, CG32682, mas1, ManI, dManI, dMas-1, alpha-Man-Ia, a-Man-Ia" IPR001382:Glycoside hydrolase family 47 CG42275 11-Aug-17 DroID_v2017_08 "Drer\man1b1b, Drer\man1a1, Drer\man1a2, Drer\man1b1a" "Scer\MNS1, Scer\MNL2" "Cele\mans-2, Cele\mans-4, Cele\mans-1, Cele\mans-3" "Xtro\man1c1, Xtro\man1b1, Xtro\man1a1, Xtro\man1a2" "Mmus\Man1a2, Mmus\Man1b1, Mmus\Man1c1, Mmus\Man1a" "Hsap\MAN1C1, Hsap\MAN1A1, Hsap\MAN1B1, Hsap\MAN1A2" " adult stage , embryonic stage | late , pupal stage | late , embryonic stage | 0-3hr , embryonic stage | mid-late , embryonic stage | early , embryonic stage -- adult stage , embryonic stage | stage 14 " " adult head

, larval muscle system

, embryonic central nervous system | presumptive

, tracheal system

" FBgn0052579 CG32579 - http://flybase.org/reports/FBgn0052579 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR018629 CG32579 IPR018629:XK-related protein CG32579 11-Aug-17 DroID_v2017_08 "Drer\xkr6b, Drer\si:ch211-195b13.6, Drer\xkr8.3, Drer\xkr5, Drer\zgc:198371, Drer\xkr9, Drer\xkr8.2, Drer\zgc:123035, Drer\xkr8.1, Drer\xkr6a, Drer\LOC100000884, Drer\xkr7" - Cele\ced-8 "Xtro\xkr4, Xtro\xkr6, Xtro\xkr9, Xtro\xkr5, Xtro\xkr8, Xtro\xkr7" "Mmus\Xkr4, Mmus\Xkr5, Mmus\Xkr7, Mmus\Xkr6, Mmus\Xkr9, Mmus\Xkr8" "Hsap\XKR8, Hsap\XKR5, Hsap\XKR6, Hsap\XKR7, Hsap\XKR4, Hsap\XKR9" "viable,fertile" FBgn0036684 CG3764 - http://flybase.org/reports/FBgn0036684 protein_coding_gene - - - CG3764 "IPR028084:Folliculin-interacting protein, N-terminal domain, IPR028086:Folliculin-interacting protein, C-terminal domain, IPR028085:Folliculin-interacting protein, middle domain, IPR026156:Folliculin-interacting protein family" CG3764 11-Aug-17 DroID_v2017_08 "Drer\fnip1, Drer\si:ch211-42i9.8" - Cele\T04C4.1 "Xtro\fnip2, Xtro\fnip1" "Mmus\Fnip1, Mmus\Fnip2" "Hsap\RAPGEF6, Hsap\FNIP1, Hsap\FNIP2" viable FBgn0261859 CG42788 - http://flybase.org/reports/FBgn0261859 protein_coding_gene - - cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 "CG42788, CG6960, CG18442, CG31304, anon-WO0118547.79, CG6934" "IPR029071:Ubiquitin-related domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR000299:FERM domain, IPR001202:WW domain, IPR001478:PDZ domain, IPR019748:FERM central domain, IPR019749:Band 4.1 domain" CG42788 11-Aug-17 DroID_v2017_08 "Drer\frmpd4, Drer\frmpd3, Drer\frmpd1b, Drer\tlr7, Drer\frmpd1" - Cele\frm-8 "Xtro\frmpd3, Xtro\frmpd4" "Mmus\Frmpd1, Mmus\Frmpd3, Mmus\Frmpd4" "Hsap\FRMPD4, Hsap\FRMPD3, Hsap\FRMPD1" FBgn0060580 l(3)S095108b lethal (3) S095108b http://flybase.org/reports/FBgn0060580 gene - - - "0951/08, l(3)S095108b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0040733 CG15068 - http://flybase.org/reports/FBgn0040733 protein_coding_gene - - - "CT34939, CG15068" IPR013172:Immune-induced protein Dim CG15068 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260447 CR11386 - http://flybase.org/reports/FBgn0260447 pseudogene_attribute - - - "CR11386, CG11386" - CR11386 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0261837 pre-mod(mdg4)-T - http://flybase.org/reports/FBgn0261837 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42769, pre-mod(mdg4)-T, Pre-MOD(MDG4)-T" "IPR007588:Zinc finger, FLYWCH-type" CG42769 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037086 CG7202 - http://flybase.org/reports/FBgn0037086 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7202 - CG7202 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0000343 coi coitus interruptus http://flybase.org/reports/FBgn0000343 - gene - copulation ; GO:0007620 | non-traceable author statement - coi - - 11-Aug-17 DroID_v2017_08 - - - - - - "mating defective,male" spermatozoon FBgn0030033 CG1387 - http://flybase.org/reports/FBgn0030033 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG1387 - CG1387 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0041711 yellow-e yellow-e http://flybase.org/reports/FBgn0041711 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG9792, yellow-e, yell-e, e" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG9792 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\C24H12.1, Cele\F49E11.8, Cele\fbxa-76, Cele\T27A1.3" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 "viable,fertile" FBgn0025181 fs(1)11-1505 fs(1)11-1505 http://flybase.org/reports/FBgn0025181 - gene - - - "11-1505, fs(1)11-1505" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0060552 l(3)S097907b lethal (3) S097907b http://flybase.org/reports/FBgn0060552 gene - - - "0979/07, l(3)S097907b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005482 l(1)ts1299 lethal (1) ts1299 http://flybase.org/reports/FBgn0005482 - gene - - - l(1)ts1299 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0262995 CR43303 - http://flybase.org/reports/FBgn0262995 non_protein_coding_gene - - - CR43303 - CR43303 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065133 l(3)SH127 lethal (3) SH127 http://flybase.org/reports/FBgn0065133 gene - - - "l(3)SH127, l(2)SH3 127" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036984 CG13248 - http://flybase.org/reports/FBgn0036984 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002293 "CG13248, CAT-4" "IPR002293:Amino acid/polyamine transporter I, IPR029485:Cationic amino acid transporter, C-terminal" CG13248 11-Aug-17 DroID_v2017_08 "Drer\slc7a14b, Drer\zgc:175280, Drer\slc7a14a, Drer\slc7a1, Drer\slc7a3a, Drer\slc7a4, Drer\slc7a2, Drer\slc7a3b, Drer\zgc:63694" "Scer\SAM3, Scer\DIP5, Scer\TAT2, Scer\TAT1, Scer\AGP3, Scer\PUT4, Scer\AGP2, Scer\UGA4, Scer\ALP1, Scer\BAP3, Scer\HIP1, Scer\CAN1, Scer\GNP1, Scer\GAP1, Scer\MMP1, Scer\BAP2, Scer\AGP1, Scer\SSY1, Scer\LYP1" "Cele\aat-5, Cele\Y53F4B.12, Cele\B0454.6, Cele\C50D2.2, Cele\F23F1.6" "Xtro\slc7a2.1, Xtro\slc7a2.2, Xtro\slc7a1, Xtro\slc7a14, Xtro\slc7a4, Xtro\slc7a3" "Mmus\Slc7a3, Mmus\Slc7a1, Mmus\Slc7a4, Mmus\Slc7a2, Mmus\AU018091, Mmus\Slc7a14" "Hsap\SLC7A14, Hsap\SLC7A1, Hsap\SLC7A4, Hsap\SLC7A2, Hsap\SLC7A3" viable FBgn0043976 Su(tor)337-73 Su(tor)337-73 http://flybase.org/reports/FBgn0043976 gene - - - "337-73, Su(tor)337-73" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085736 CG40472 - http://flybase.org/reports/FBgn0085736 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with HGNC_gene:NDUFB2; HGNC:7697 "CG40472, CR40472, ND-AGGGL" IPR026627:NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 CG40472 11-Aug-17 DroID_v2017_08 Drer\ndufb2 - Cele\F44G4.2 Xtro\ndufb2 Mmus\Ndufb2 Hsap\NDUFB2 FBgn0031472 CG2983 - http://flybase.org/reports/FBgn0031472 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 "CG2983, dC1GalT8" IPR003378:Fringe-like CG2983 11-Aug-17 DroID_v2017_08 "Drer\LOC564281, Drer\c1galt1b, Drer\c1galt1c1, Drer\c1galt1a, Drer\si:dkey-202e17.1" - "Cele\E03H4.3, Cele\C17A2.3, Cele\Y38C1AB.1, Cele\F56H6.1, Cele\F37A4.3, Cele\C38H2.2, Cele\C16D9.6, Cele\C02H6.1, Cele\T09E11.12, Cele\Y38C1AB.5, Cele\bus-4, Cele\W09D10.5" "Xtro\c1galt1, Xtro\LOC100496837" "Mmus\C1galt1c1, Mmus\C1galt1" "Hsap\C1GALT1, Hsap\C1GALT1C1" viable FBgn0261583 CG42693 - http://flybase.org/reports/FBgn0261583 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42693 - CG42693 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001744 l(1)HM14 lethal (1) HM14 http://flybase.org/reports/FBgn0001744 - gene - - - l(1)HM14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0262587 CG43124 - http://flybase.org/reports/FBgn0262587 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 molecular_function ; GO:0003674 | no biological data available proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43124 "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG43124 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259249 EP-63 - http://flybase.org/reports/FBgn0259249 gene - - - EP-63 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0038874 ETHR ETHR http://flybase.org/reports/FBgn0038874 protein_coding_gene thyrotropin-releasing hormone receptor activity ; GO:0004997 | inferred from electronic annotation with InterPro:IPR002120 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity ecdysis-triggering hormone receptor activity ; GO:0042654 | inferred from direct assay G-protein coupled peptide receptor activity ; GO:0008528 | inferred from sequence or structural similarity with TkR86C ecdysis-triggering hormone receptor activity ; GO:0042654 | inferred from physical interaction with ETH hormone-mediated signaling pathway ; GO:0009755 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with TkR86C integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0042654 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with TkR86C "CG5911, CG5911b, CG5911a, anon-WO0170980.38, anon-WO0170980.37, ETHR, Dm ETHRa" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM, IPR002120:Thyrotropin-releasing hormone receptor" CG5911 11-Aug-17 DroID_v2017_08 "Drer\trhr2, Drer\trhrb, Drer\tmtops3a, Drer\ghsra, Drer\trhra, Drer\LOC108179223" - "Cele\R07D5.2, Cele\nmur-2, Cele\nmur-4, Cele\nmur-3, Cele\F54E4.2, Cele\nmur-1, Cele\npr-34" "Xtro\ghsr, Xtro\trhr2, Xtro\trhr, Xtro\trhr3, Xtro\nmur2" "Mmus\Ghsr, Mmus\Nmur1, Mmus\Trhr2, Mmus\Nmur2, Mmus\Trhr" "Hsap\NMUR1, Hsap\NMUR2, Hsap\GHSR, Hsap\TRHR" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0029975 spidey spidey http://flybase.org/reports/FBgn0029975 protein_coding_gene - positive regulation of lipid storage ; GO:0010884 | inferred from mutant phenotype negative regulation of DNA endoreduplication ; GO:0032876 | inferred from mutant phenotype negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype cellular response to nutrient levels ; GO:0031669 | inferred from mutant phenotype negative regulation of phosphatidylinositol 3-kinase signaling ; GO:0014067 | inferred from mutant phenotype - "CG1444, KAR, KAR[CG1444], spidey, Kar" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG1444 11-Aug-17 DroID_v2017_08 "Drer\hsd17b12b, Drer\hsdl1, Drer\hsd17b12a, Drer\hsd17b3, Drer\hsd20b2" Scer\IFA38 "Cele\let-767, Cele\dhs-27, Cele\dhs-5, Cele\stdh-3, Cele\stdh-4, Cele\stdh-2, Cele\stdh-1" "Xtro\hsd17b12, Xtro\hsdl1, Xtro\LOC100497556" "Mmus\Hsd17b3, Mmus\Hsdl1, Mmus\Hsd17b12" "Hsap\HSDL1, Hsap\HSD17B3, Hsap\HSD17B12" "viable,fertile,some die during larval stage" embryonic/larval tracheal system | larval stage FBgn0037594 Or85d Odorant receptor 85d http://flybase.org/reports/FBgn0037594 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "85d, DOR114, 85A.2, 85.2, CG11742, Or85d" "IPR004117:Olfactory receptor, insect" CG11742 11-Aug-17 DroID_v2017_08 - - Cele\T11F8.1 - - - "viable,fertile" FBgn0025507 l(2)59ABc lethal (2) 59ABc http://flybase.org/reports/FBgn0025507 - gene - - - l(2)59ABc - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0038679 CG6040 - http://flybase.org/reports/FBgn0038679 protein_coding_gene - - - CG6040 - CG6040 11-Aug-17 DroID_v2017_08 - - Cele\ZC455.1 - - - "viable,visible" "chaeta,supernumerary" FBgn0029171 Fas1::hh Fas1::hh http://flybase.org/reports/FBgn0029171 engineered_fusion_gene - - - Fas1::hh - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing disc,anterior compartment" FBgn0085721 CG41614 - http://flybase.org/reports/FBgn0085721 protein_coding_gene - - - CG41614 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028166 l(3)S030305 lethal (3) S030305 http://flybase.org/reports/FBgn0028166 gene - - - "0303/05, l(3)S030305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0052201 CG32201 - http://flybase.org/reports/FBgn0052201 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 extracellular region ; GO:0005576 | inferred from sequence model "CG18230, CG13382, CG32201" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG32201 11-Aug-17 DroID_v2017_08 "Drer\zgc:152670, Drer\zgc:158254, Drer\p4ha1a, Drer\p4ha3, Drer\p4ha1b, Drer\p4ha2, Drer\p4htm" - "Cele\phy-2, Cele\C14E2.4, Cele\phy-3, Cele\phy-4, Cele\Y43F8B.19" "Xtro\p4ha2, Xtro\p4ha3, Xtro\p4ha1" "Mmus\P4htm, Mmus\P4ha3, Mmus\P4ha2, Mmus\P4ha1" "Hsap\P4HTM, Hsap\P4HA3, Hsap\P4HA1, Hsap\P4HA2" viable FBgn0019793 l(1)11 lethal (1) 11 http://flybase.org/reports/FBgn0019793 - gene - - - l(1)11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001760 l(1)M11 lethal (1) M11 http://flybase.org/reports/FBgn0001760 - gene - - - l(1)M11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0051485 tRNA:Lys-CTT-2-1Psi transfer RNA:Lysine-CTT 2-1 pseudogene http://flybase.org/reports/FBgn0051485 pseudogene_attribute - - - "CR31485, AE002699.trna6-LysCTT, tRNA:KPsi:CTT:AE002699, chr3R.trna79-LysCTT, tRNA:Lys-CTT-2-1Psi, tRNA:CR31485:Psi" - CR31485 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038577 CG12321 - http://flybase.org/reports/FBgn0038577 protein_coding_gene - proteasome assembly ; GO:0043248 | inferred from biological aspect of ancestor with PANTHER:PTN001403976 proteasome complex ; GO:0000502 | colocalizes_with inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001403976 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001403976 CG12321 IPR019151:Proteasome assembly chaperone 2 CG12321 11-Aug-17 DroID_v2017_08 Drer\psmg2 Scer\ADD66 "Cele\K08H2.4, Cele\K08H2.2" Xtro\psmg2 Mmus\Psmg2 Hsap\PSMG2 viable FBgn0034814 CG9890 - http://flybase.org/reports/FBgn0034814 protein_coding_gene RNA polymerase II core promoter sequence-specific DNA binding ; GO:0000979 | inferred from biological aspect of ancestor with PANTHER:PTN000327673 - - "ld46465, anon-EST:Posey169, CG9890" IPR013087:Zinc finger C2H2-type CG9890 11-Aug-17 DroID_v2017_08 Drer\znf277 - Cele\ztf-7 Xtro\znf277 Mmus\Zfp277 Hsap\ZNF277 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC25594 K -0.055749845 0.626669257 -1.378642256 1.398917848 -1.590052543 -1.323099221 FBgn0039538 CG12883 - http://flybase.org/reports/FBgn0039538 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12883 - CG12883 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261522 CR42657 - http://flybase.org/reports/FBgn0261522 non_protein_coding_gene - - - "CG42657, CR42657" - CR42657 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039020 CG17141 - http://flybase.org/reports/FBgn0039020 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006073, InterPro:IPR030378" - - CG17141 "IPR006073:GTP binding domain, IPR016478:GTPase, MTG1, IPR030378:Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR023179:GTP-binding protein, orthogonal bundle domain" CG17141 11-Aug-17 DroID_v2017_08 Drer\mtg1 Scer\MTG1 Cele\Y67D2.4 Xtro\mtg1 Mmus\Mtg1 Hsap\MTG1 FBgn0037455 CG2336 - http://flybase.org/reports/FBgn0037455 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR016161 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR016161, InterPro:IPR016163" - CG2336 "IPR009961:Protein of unknown function DUF1487, IPR016161:Aldehyde/histidinol dehydrogenase" CG2336 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033845 mars mars http://flybase.org/reports/FBgn0033845 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B microtubule binding ; GO:0008017 | inferred from direct assay signaling ; GO:0023052 | inferred from electronic annotation with InterPro:IPR005026 centrosome localization ; GO:0051642 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from genetic interaction with Tlk mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from direct assay kinetochore assembly ; GO:0051382 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype spindle ; GO:0005819 | inferred from direct assay spindle pole ; GO:0000922 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay spindle microtubule ; GO:0005876 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay kinetochore microtubule ; GO:0005828 | colocalizes_with inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "dhrp/gkap, CG17064, gkap, mars, HURP, Mars, D-HURP" IPR005026:SAPAP family CG17064 11-Aug-17 DroID_v2017_08 "Drer\dlgap2a, Drer\dlgap4a, Drer\dlgap3, Drer\dlgap1a, Drer\dlgap1b, Drer\dlgap4b, Drer\dlgap5" - - "Xtro\dlgap3, Xtro\dlgap2, Xtro\dlgap5, Xtro\dlgap4" "Mmus\Dlgap3, Mmus\Dlgap4, Mmus\Dlgap2, Mmus\Dlgap1, Mmus\Dlgap5" "Hsap\DLGAP1, Hsap\DLGAP2, Hsap\DLGAP3, Hsap\DLGAP4, Hsap\DLGAP5" "mitotic cell cycle defective,chemical sensitive,viable,fertile,grandchildless,partially,conditional,lethal,temperature conditional,female sterile,visible,increased cell death,hatching behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,chemical resistant,majority die during embryonic stage" "mitotic spindle,centrosome,centrosome | conditional | embryonic stage 4,nucleus | conditional | embryonic stage 4,spindle | conditional | embryonic stage 4,spindle pole | conditional | embryonic stage 4,spindle,egg,embryo,eye disc,eye,meiotic spindle,mitotic spindleda.G32,spindle poleda.G32,mitotic spindlemat.‘±Tub67C.THsimVP16,spindle polemat.‘±Tub67C.THsimVP16,centrosomemat.‘±Tub67C.THsimVP16,nucleusmat.‘±Tub67C.THsimVP16" FBgn0267317 CR45753 - http://flybase.org/reports/FBgn0267317 non_protein_coding_gene - - - CR45753 - CR45753 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267255 CG45691 - http://flybase.org/reports/FBgn0267255 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lincRNA.169, CG45691" - CG45691 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261386 Gpa2 Glycoprotein hormone alpha 2 http://flybase.org/reports/FBgn0261386 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Gpb5 G-protein coupled receptor binding ; GO:0001664 | contributes_to inferred from physical interaction with Lgr1 hormone activity ; GO:0005179 | contributes_to inferred from direct assay hormone-mediated signaling pathway ; GO:0009755 | inferred from direct assay extracellular space ; GO:0005615 | inferred by curator from GO:0005179 "GPA2, Gpa2, CG17878, gpa2" "IPR029034:Cystine-knot cytokine, IPR006208:Glycoprotein hormone subunit beta, cystine knot" CG17878 11-Aug-17 DroID_v2017_08 Drer\gpha2 - Cele\flr-2 - Mmus\Gpha2 Hsap\GPHA2 FBgn0259577 GG01286 - http://flybase.org/reports/FBgn0259577 gene - - - GG01286 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein L3,distal,wing cell" FBgn0085194 CG34165 - http://flybase.org/reports/FBgn0085194 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34165 - CG34165 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020889 Su(osk)P2 Suppressor of oskar P2 http://flybase.org/reports/FBgn0020889 - gene - - - "P2, Su(osk)P2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039927 CG11155 - http://flybase.org/reports/FBgn0039927 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity with HGNC:4579 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 regulation of synaptic activity ; GO:0060025 | inferred from sequence or structural similarity with GluRIIA neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with GluRIIA "CT30863, CG11155, DmelCG11155" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG11155 11-Aug-17 DroID_v2017_08 "Drer\grik1a, Drer\LOC100331381, Drer\grik2, Drer\LOC100334689, Drer\grik4, Drer\grid1a, Drer\LOC100537813, Drer\grik1b, Drer\grid1b, Drer\grik5, Drer\grid2" - "Cele\glr-6, Cele\glr-7, Cele\F59E12.8, Cele\glr-3, Cele\glr-4, Cele\glr-5, Cele\glr-8" "Xtro\grik1, Xtro\grik4" "Mmus\Grik2, Mmus\Grik5, Mmus\Grid2, Mmus\Grik1, Mmus\Grid1, Mmus\Grik3, Mmus\Grik4" "Hsap\GRID2, Hsap\GRIK5, Hsap\GRIK1, Hsap\GRIK3, Hsap\GRIK2, Hsap\GRID1, Hsap\GRIK4" viable FBgn0052200 tRNA:Pro-CGG-2-3 transfer RNA:Proline-CGG 2-3 http://flybase.org/reports/FBgn0052200 tRNA_gene CCG codon-amino acid adaptor activity ; GO:0033424 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033424 cytosol ; GO:0005829 | inferred by curator from GO:0033424 "AE002602.trna26-ProCGG, tRNA:P:CGG:AE002602-b, CR32200, chr3L.trna31-ProCGG, tRNA-Pro-CGG-2-3, tRNA:Pro-CGG-2-3, tRNA:CR32200, CCG" - CR32200 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033633 Smyd4-3 "SET and MYND domain containing, class 4, member 3" http://flybase.org/reports/FBgn0033633 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 cytoplasm ; GO:0005737 | inferred from direct assay "Smyd4-3, CG7759" "IPR002893:Zinc finger, MYND-type, IPR011990:Tetratricopeptide-like helical domain, IPR001214:SET domain, IPR019734:Tetratricopeptide repeat" CG7759 11-Aug-17 DroID_v2017_08 "Drer\smyd2a, Drer\smyd1a, Drer\smyd4, Drer\smyd3, Drer\smyd2b, Drer\smyd1b" "Scer\SET6, Scer\SET5" "Cele\set-10, Cele\set-18, Cele\set-3" "Xtro\smyd4, Xtro\smyd1, Xtro\smyd5" "Mmus\Zmynd15, Mmus\Smyd3, Mmus\Smyd2, Mmus\Smyd1, Mmus\Smyd5, Mmus\Smyd4" "Hsap\SMYD2, Hsap\SMYD3, Hsap\ZMYND15, Hsap\SMYD4, Hsap\SMYD1, Hsap\SMYD5" "viable,fertile" FBgn0061503 l(2)44Fm lethal (2) 44Fm http://flybase.org/reports/FBgn0061503 gene - - - l(2)44Fm - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029958 Pdp Pyruvate dehydrogenase phosphatase http://flybase.org/reports/FBgn0029958 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from electronic annotation with InterPro:IPR015655 phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement [pyruvate dehydrogenase (lipoamide)] phosphatase activity ; GO:0004741 | inferred from sequence or structural similarity with UniProtKB:Q9P0J1 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with UniProtKB:Q9P0J1 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:Q9P0J1 protein dephosphorylation ; GO:0006470 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q9P0J1 "153332_at, Pdp, CG12151, pdp, PDP" "IPR001932:PPM-type phosphatase domain, IPR015655:Protein phosphatase 2C family" CG12151 11-Aug-17 DroID_v2017_08 "Drer\pdp2, Drer\si:ch211-15p9.2, Drer\pdp1" "Scer\PTC4, Scer\PTC5" Cele\pdp-1 "Xtro\pdp2, Xtro\pdp1" "Mmus\Pdp1, Mmus\Pdp2" "Hsap\PDP2, Hsap\PDP1" "viable,fertile,thermotaxis behavior defective" FBgn0053538 tRNA:Arg-CCT-1-3 transfer RNA:Arginine-CCT 1-3 http://flybase.org/reports/FBgn0053538 tRNA_gene AGG codon-amino acid adaptor activity ; GO:0033448 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033448 cytosol ; GO:0005829 | inferred by curator from GO:0033448 "AE002787.trna57-ArgCCT, tRNA:R:CCT:AE002787-b, CR33538, chr2R.trna41-ArgCCT, tRNA-Arg-CCT-1-3, tRNA:Arg-CCT-1-3, tRNA:CR33538, AGG" - CR33538 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000689 flrdM flight reduced M http://flybase.org/reports/FBgn0000689 - gene - - - flrdM - - 11-Aug-17 DroID_v2017_08 - - - - - - "jumping defective,hypoactive,flight defective" FBgn0069241 fnu fnu http://flybase.org/reports/FBgn0069241 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available fnu - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086056 snoRNA:Me18S-A425 - http://flybase.org/reports/FBgn0086056 snoRNA_gene - - - "snoRNA:Me18S-A425, Me18S-Am425, Me18S-A425(Dm425), CR34685, Dm425" - CR34685 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030503 Tango2 Transport and Golgi organization 2 http://flybase.org/reports/FBgn0030503 protein_coding_gene molecular_function ; GO:0003674 | no biological data available Golgi organization ; GO:0007030 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG11176, TANGO2, Tango2" IPR008551:Transport and Golgi organisation protein 2 CG11176 11-Aug-17 DroID_v2017_08 Drer\tango2 Scer\YGR127W "Cele\Y80D3A.9, Cele\R186.1" Xtro\tango2 Mmus\Tango2 Hsap\TANGO2 viable FBgn0010762 simj simjang http://flybase.org/reports/FBgn0010762 "FBgn0011360, FBgn0011522, FBgn0036097, FBgn0036098, FBgn0052067, FBgn0062069" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Mi-2 cardiac cell fate specification ; GO:0060912 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay NuRD complex ; GO:0016581 | inferred from physical interaction with Mi-2 "CG32067, p66, CG7983, l(3)01814, CG8000, l(3)rN672, l(3)j4A5, anon-WO0118547.361, simj, dp66, p66/68-like, SIMJ" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR032346:Transcriptional repressor p66, coiled-coil MBD2-interaction domain" CG32067 11-Aug-17 DroID_v2017_08 "Drer\gatad2ab, Drer\ndufa13, Drer\gatad2b" - Cele\dcp-66 "Xtro\gatad2a, Xtro\gatad2b" "Mmus\Gatad2a, Mmus\Gatad2b" "Hsap\NYNRIN, Hsap\GATAD2A, Hsap\GATAD2B" "viable,fertile,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,melanotic necrosis,lethal - all die before end of larval stage,some die during larval stage,visible,lethal - all die before end of first instar larval stage,some die during first instar larval stage,learning defective,neuroanatomy defective" "cardioblast,leg,mesothoracic tergum,wing,pupal abdomen,heart primordium,metathoracic leg,scutellar bristle,supernumerary,embryonic/larval neuromuscular junction | third instar larval stage,presynaptic active zone, with Dcr-2UAS.cDa, elav.PU" FBgn0030594 CG9509 - http://flybase.org/reports/FBgn0030594 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 mesoderm development ; GO:0007498 | inferred from expression pattern ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG9509, Dm GMCbeta2" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9509 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0005238 l(3)R70 lethal of Roberts 70 http://flybase.org/reports/FBgn0005238 - gene - - - "l(3)B70, l(3)R70" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0042138 CG18815 - http://flybase.org/reports/FBgn0042138 protein_coding_gene palmitoyl-(protein) hydrolase activity ; GO:0008474 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay protein depalmitoylation ; GO:0002084 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 cytoplasm ; GO:0005737 | inferred from direct assay "anon-EST:Posey232, CG18815, APT1" "IPR003140:Phospholipase/carboxylesterase/thioesterase, IPR029058:Alpha/Beta hydrolase fold" CG18815 11-Aug-17 DroID_v2017_08 "Drer\lypla1, Drer\lyplal1, Drer\lypla2" Scer\YLR118C "Cele\mfb-1, Cele\ath-1" "Xtro\lypla2, Xtro\lypla1, Xtro\lyplal1" "Mmus\Lypla1, Mmus\Lyplal1, Mmus\Lypla2" "Hsap\LYPLAL1, Hsap\LYPLA2, Hsap\LYPLA1" viable FBgn0250868 CG42239 - http://flybase.org/reports/FBgn0250868 protein_coding_gene - - - CG42239 - CG42239 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039734 Tace Tace http://flybase.org/reports/FBgn0039734 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from direct assay membrane protein ectodomain proteolysis ; GO:0006509 | inferred from sequence or structural similarity with HGNC:195 membrane protein ectodomain proteolysis ; GO:0006509 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:195 "DTACE, TACE, CT23908, CG7908, Tace, TNF-alpha converting enzyme" "IPR001590:Peptidase M12B, ADAM/reprolysin, IPR001762:Disintegrin domain, IPR024079:Metallopeptidase, catalytic domain, IPR034025:ADAM10/ADAM17 catalytic domain, IPR002870:Peptidase M12B, propeptide, IPR032029:ADAM17, membrane-proximal domain" CG7908 11-Aug-17 DroID_v2017_08 "Drer\adam8b, Drer\adam17a, Drer\adam15, Drer\adam10b, Drer\adam11, Drer\adam12, Drer\adam22, Drer\si:ch1073-396h14.1, Drer\adam17b" - "Cele\adm-2, Cele\unc-71, Cele\adm-4" "Xtro\adam17, Xtro\adam10" "Mmus\Adam25, Mmus\Adam12, Mmus\Adam11, Mmus\Adam10, Mmus\Adam8, Mmus\Adam22, Mmus\Adam17, Mmus\Adam28, Mmus\Adam9, Mmus\Adam15" "Hsap\ADAM11, Hsap\ADAM28, Hsap\ADAM22, Hsap\ADAM12, Hsap\ADAM15, Hsap\ADAM17, Hsap\ADAM10, Hsap\ADAM8, Hsap\ADAM9" "wild-type,viable" FBgn0061100 l(3)S009418 lethal (3) S009418 http://flybase.org/reports/FBgn0061100 gene - - - "0094/18, l(3)S009418" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011250 ms(3)72D male sterile (3) 72D http://flybase.org/reports/FBgn0011250 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(3)03957, ry72D, ms(3)ry72D, ms(3)72D" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0265295 pncr014:3L putative noncoding RNA 014:3L http://flybase.org/reports/FBgn0265295 non_protein_coding_gene - - - "pncr014:3L, CR33944, BEST:LD13184, CR42871" - CR42871 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010195 x3 x3 http://flybase.org/reports/FBgn0010195 - gene - - - x3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050487 CG30487 - http://flybase.org/reports/FBgn0050487 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs33e02.y1, NEST:bs16h04, CG30487" - CG30487 11-Aug-17 DroID_v2017_08 Drer\oser1 - Cele\F02E9.5 Xtro\oser1 Mmus\Oser1 Hsap\OSER1 "viable,male fertile,female fertile" FBgn0259185 Ir60b Ionotropic receptor 60b http://flybase.org/reports/FBgn0259185 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir60b, CG13582, DmelIR60b, CG42289, IR60b" - CG42289 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043560 Su(hh)VII Su(hh)VII http://flybase.org/reports/FBgn0043560 gene - - - Su(hh)VII - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037305 CG12173 - http://flybase.org/reports/FBgn0037305 protein_coding_gene magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR023943 acireductone synthase activity ; GO:0043874 | inferred from biological aspect of ancestor with PANTHER:PTN000463822 L-methionine biosynthetic process from methylthioadenosine ; GO:0019509 | inferred from biological aspect of ancestor with PANTHER:PTN000463822 - "CG12173, 24644163" "IPR006439:HAD hydrolase, subfamily IA, IPR023943:Enolase-phosphatase E1, IPR027511:Enolase-phosphatase E1, eukaryotes, IPR023214:HAD-like domain" CG12173 11-Aug-17 DroID_v2017_08 Drer\enoph1 Scer\UTR4 Cele\F58H1.3 Xtro\enoph1 Mmus\Enoph1 Hsap\ENOPH1 viable FBgn0002237 l(3)68Bd lethal (3) 68Bd http://flybase.org/reports/FBgn0002237 - gene - - - "l(3)C404, F, l(3)F, l(3)68Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible" macrochaeta FBgn0033359 CG8213 - http://flybase.org/reports/FBgn0033359 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" perivitelline space ; GO:0098595 | inferred from direct assay "SP44, c-SP44, CG8213" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG8213 11-Aug-17 DroID_v2017_08 "Drer\pik3ip1, Drer\zgc:171592, Drer\zgc:112302, Drer\zgc:112160, Drer\zgc:92511, Drer\si:dkey-57c15.4, Drer\f7i, Drer\f10, Drer\f2, Drer\ela3l, Drer\zgc:112368, Drer\zgc:163025, Drer\tmprss4b, Drer\ela2l, Drer\f9a, Drer\LOC562139, Drer\plaua, Drer\si:dkey-33i11.3, Drer\proca, Drer\ctrl, Drer\tmprss5, Drer\ela2, Drer\zgc:112285, Drer\f7, Drer\zgc:92041, Drer\zgc:92745, Drer\habp2, Drer\mst1, Drer\plg, Drer\ctrb1, Drer\f9b, Drer\zgc:154142, Drer\st14a, Drer\si:dkey-238d18.3" - - "Xtro\ctrb1, Xtro\plat, Xtro\f7, Xtro\ctrb2, Xtro\LOC100135144, Xtro\cela3a, Xtro\f2, Xtro\proc, Xtro\mst1, Xtro\habp2, Xtro\cela2a, Xtro\f10, Xtro\f9, Xtro\proz" "Mmus\Prss55, Mmus\F9, Mmus\Hpn, Mmus\Tmprss9, Mmus\Plau, Mmus\Hgf, Mmus\F7, Mmus\Cela3a, Mmus\Tmprss11c, Mmus\St14, Mmus\Ctrc, Mmus\Ctrb1, Mmus\Proc, Mmus\F10, Mmus\Plg, Mmus\Mst1, Mmus\Plat, Mmus\Habp2, Mmus\Cela3b, Mmus\Cela1, Mmus\Tmprss11f, Mmus\Hgfac, Mmus\Pik3ip1, Mmus\Cela2a, Mmus\F2, Mmus\F12, Mmus\Prss54, Mmus\Ctrl" "Hsap\HABP2, Hsap\F12, Hsap\HGF, Hsap\CTRC, Hsap\CELA1, Hsap\CELA2B, Hsap\PRSS55, Hsap\MST1L, Hsap\F2, Hsap\PRSS54, Hsap\F7, Hsap\PLG, Hsap\PROC, Hsap\CTRB2, Hsap\CELA3B, Hsap\F10, Hsap\CELA3A, Hsap\CTRL, Hsap\FNDC1, Hsap\CTRB1, Hsap\HPN, Hsap\CELA2A, Hsap\F9, Hsap\PIK3IP1, Hsap\TMPRSS11F, Hsap\PLAU, Hsap\HGFAC, Hsap\MST1, Hsap\PLAT, Hsap\ST14" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0025468 tin::Drer\Nkx2.5 Nkx2.5 http://flybase.org/reports/FBgn0025468 - engineered_fusion_gene - - - "tin::Brer\Nkx2.5, tin::Drer\Nkx2.5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262599 SmydA-3 "SET and MYND domain containing, arthropod-specific, member 3" http://flybase.org/reports/FBgn0262599 protein_coding_gene - - - "CG17085, CG17086, SmydA-3, CG43129" IPR001214:SET domain CG43129 11-Aug-17 DroID_v2017_08 "Drer\erlin2, Drer\smyd2a, Drer\smyd1a, Drer\erlin1, Drer\smyd4, Drer\smyd2b, Drer\smyd1b, Drer\smyd3" "Scer\SET6, Scer\SET5" "Cele\erl-1, Cele\set-18" "Xtro\erlin2, Xtro\smyd1, Xtro\smyd4, Xtro\erlin1, Xtro\smyd5" "Mmus\Smyd3, Mmus\Smyd2, Mmus\Smyd4, Mmus\Erlin2, Mmus\Smyd1, Mmus\Erlin1, Mmus\Smyd5" "Hsap\SMYD4, Hsap\ERLIN1, Hsap\SMYD5, Hsap\SMYD3, Hsap\SMYD1, Hsap\SMYD2" FBgn0039022 CG4725 - http://flybase.org/reports/FBgn0039022 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "neuropeptide signaling pathway ; GO:0007218 | inferred from electronic annotation with InterPro:IPR029736 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" extracellular region ; GO:0005576 | inferred from direct assay CG4725 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR029736:Endothelin-converting enzyme-like 1" CG4725 11-Aug-17 DroID_v2017_08 "Drer\mmel1, Drer\phex, Drer\ece2b, Drer\ece1" - "Cele\nep-12, Cele\nep-13, Cele\nep-7, Cele\nep-24, Cele\nep-20, Cele\nep-16, Cele\nep-6, Cele\nep-5, Cele\nep-18, Cele\nep-21, Cele\nep-8, Cele\nep-9, Cele\nep-23, Cele\nep-17, Cele\nep-10, Cele\nep-26, Cele\nep-19, Cele\nep-3" "Xtro\ecel1, Xtro\ece2, Xtro\ece1, Xtro\mmel1" "Mmus\Kel, Mmus\Ecel1, Mmus\Ece1, Mmus\Phex, Mmus\Mme, Mmus\Ece2, Mmus\Mmel1" "Hsap\MME, Hsap\ECE2, Hsap\MMEL1, Hsap\PHEX, Hsap\ECE1, Hsap\ECEL1, Hsap\KEL" viable FBgn0086371 poly poly http://flybase.org/reports/FBgn0086371 protein_coding_gene insulin receptor binding ; GO:0005158 | inferred from direct assay oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from direct assay melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from mutant phenotype Elongator holoenzyme complex ; GO:0033588 | inferred from electronic annotation with InterPro:IPR018627 cellular_component ; GO:0005575 | no biological data available "did/alt1, poly, did, CG9829, l(3)S008131, 0081/31, l(3)05137" IPR018627:Elongation complex protein 6 CG9829 11-Aug-17 DroID_v2017_08 Drer\elp6 - - Xtro\elp6 Mmus\Elp6 Hsap\ELP6 FBgn0033203 CG2070 - http://flybase.org/reports/FBgn0033203 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - - CG2070 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG2070 11-Aug-17 DroID_v2017_08 "Drer\zgc:64106, Drer\rdh14b, Drer\si:dkey-23o4.6, Drer\cbr1, Drer\dhrs13l1, Drer\flj13639, Drer\si:ch211-107o10.3, Drer\zgc:112332, Drer\si:dkey-174n20.1, Drer\dhrsx, Drer\dhrs12, Drer\rdh12l, Drer\dhrs13a.3, Drer\zgc:153441, Drer\si:dkey-94e7.2, Drer\rdh12, Drer\cbr1l, Drer\dhrs13a.1, Drer\dhrs13a.2, Drer\si:dkey-73n8.3, Drer\si:ch211-165b10.3, Drer\ascc1, Drer\rdh14a" "Scer\YNL181W, Scer\YKL107W, Scer\GPI11, Scer\ENV9" "Cele\E04F6.15, Cele\C27D8.4, Cele\K10H10.6, Cele\DC2.5, Cele\dhs-22" "Xtro\rdh14, Xtro\dhrs13, Xtro\dhrs12, Xtro\rdh11, Xtro\dhrsx, Xtro\rdh13, Xtro\ascc1" "Mmus\Dhrsx, Mmus\1700003E16Rik, Mmus\Cbr3, Mmus\Dhrs13, Mmus\Ascc1, Mmus\Rdh11, Mmus\Rdh13, Mmus\Rdh14, Mmus\Wwox, Mmus\Rdh12, Mmus\Cbr1" "Hsap\DHRS12, Hsap\RDH13, Hsap\DHRSX, Hsap\C2orf81, Hsap\RDH11, Hsap\CBR1, Hsap\CBR3, Hsap\DHRS13, Hsap\RDH12, Hsap\OSTC, Hsap\RDH14" lethal FBgn0004964 l(1)17Cb lethal (1) 17Cb http://flybase.org/reports/FBgn0004964 - gene - - - "13C, l(1)17Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0004898 fd96Cb forkhead domain 96Cb http://flybase.org/reports/FBgn0004898 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000930792 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "CG11922, Dmfd5, FD5, fd5, fd96Cb" "IPR018122:Fork head domain conserved site1, IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG11922 11-Aug-17 DroID_v2017_08 "Drer\foxb1a, Drer\zgc:162612, Drer\foxj1a, Drer\foxg1a, Drer\foxk2, Drer\foxd1, Drer\si:ch211-262e15.1, Drer\foxl1, Drer\foxb2, Drer\foxj2, Drer\foxd2, Drer\foxe1, Drer\foxk1, Drer\foxe3, Drer\foxb1b, Drer\foxd3, Drer\foxd5, Drer\foxq2" "Scer\FKH2, Scer\HCM1, Scer\FKH1" "Cele\lin-31, Cele\fkh-2, Cele\fkh-10, Cele\let-381, Cele\unc-130" "Xtro\foxk2, Xtro\foxj1.2, Xtro\foxd2, Xtro\foxd3, Xtro\foxj1, Xtro\foxe3, Xtro\foxb1, Xtro\foxe1, Xtro\foxd1, Xtro\foxi4.2, Xtro\foxd4l1.1, Xtro\foxd4l1.2" "Mmus\Foxe3, Mmus\Foxk2, Mmus\Foxd4, Mmus\Foxd2, Mmus\Foxl1, Mmus\Foxk1, Mmus\Foxa3, Mmus\Foxb1, Mmus\Foxe1, Mmus\Foxb2, Mmus\Foxd3, Mmus\Foxg1, Mmus\Foxj1, Mmus\Foxd1" "Hsap\FOXD4L1, Hsap\FOXK1, Hsap\FOXD4, Hsap\FOXB1, Hsap\FOXE1, Hsap\FOXJ1, Hsap\FOXD3, Hsap\FOXD4L4, Hsap\FOXD4L5, Hsap\FOXE3, Hsap\FOXG1, Hsap\FOXA1, Hsap\FOXL1, Hsap\FOXD1, Hsap\FOXD4L6, Hsap\FOXD4L3, Hsap\FOXD2, Hsap\FOXK2, Hsap\FOXB2" embryonic stage " neuroblast

, sensory neuron

, embryonic peripheral nervous system

" viable FBgn0027648 l(2)CL-R lethal (2) Cell Lethal Right http://flybase.org/reports/FBgn0027648 - gene - - - "CL2R, l(2)CL-R" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011559 Acp36DE Accessory gland protein 36DE http://flybase.org/reports/FBgn0011559 FBgn0044574 protein_coding_gene hormone activity ; GO:0005179 | non-traceable author statement "sperm storage ; GO:0046693 | inferred from mutant phenotype negative regulation of female receptivity, post-mating ; GO:0045434 | non-traceable author statement sperm storage ; GO:0046693 | traceable author statement multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sperm competition ; GO:0046692 | inferred from direct assay sperm competition ; GO:0046692 | traceable author statement mating plug formation ; GO:0042628 | traceable author statement" extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | traceable author statement "Acp36DE, CT22109, CG7157, anon-WO0140519.55, Acp36D, Acp" - CG7157 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male " male accessory gland main cell

, male accessory gland

" "male fertile,viable,male sterile,partially,recessive,lethal" "female reproductive system,uterus" FBgn0266859 CR45320 - http://flybase.org/reports/FBgn0266859 non_protein_coding_gene - - - CR45320 - CR45320 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033936 CG17386 - http://flybase.org/reports/FBgn0033936 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG17386, CT33484" "IPR006630:RNA-binding protein Lupus La, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR024642:SUZ-C domain, IPR000504:RNA recognition motif domain" CG17386 11-Aug-17 DroID_v2017_08 "Drer\zgc:162969, Drer\larp6" - Cele\larp-5 "Xtro\larp6, Xtro\larp6" Mmus\Larp6 Hsap\LARP6 "viable,body color defective" mesothoracic tergum FBgn0065577 l(2)SH0951 lethal (2) SH0951 http://flybase.org/reports/FBgn0065577 gene - - - "l(2)SH0951, l(2)SH2 0951" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267668 CR46006 - http://flybase.org/reports/FBgn0267668 non_protein_coding_gene - - - "CR46006, CR45244, pri-mir-276b_mir-276a, CR44327" - CR46006 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065903 l(2)SH0197 lethal (2) SH0197 http://flybase.org/reports/FBgn0065903 gene - - - "l(2)SH0197, l(2)SH2 0197" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031850 Tsp Thrombospondin http://flybase.org/reports/FBgn0031850 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR003367, InterPro:IPR008859, InterPro:IPR018097, InterPro:IPR028974 heparin binding ; GO:0008201 | inferred from direct assay" muscle organ development ; GO:0007517 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype extracellular matrix ; GO:0031012 | inferred from direct assay muscle tendon junction ; GO:0005927 | inferred from direct assay protein complex ; GO:0043234 | inferred from direct assay "Tsp, CT31613, tsp, CG11326, SP295, D-TSP, DTSP" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR008859:Thrombospondin, C-terminal, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR017897:Thrombospondin, type 3 repeat, IPR009030:Growth factor receptor cysteine-rich domain, IPR024665:Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain, IPR028974:TSP type-3 repeat, IPR003367:Thrombospondin, type 3-like repeat" CG11326 11-Aug-17 DroID_v2017_08 "Drer\thbs1b, Drer\nell2b, Drer\thbs3a, Drer\thbs4b, Drer\thbs1a, Drer\comp, Drer\thbs4a, Drer\thbs2b, Drer\thbs3b, Drer\thbs2a, Drer\nell2a" - - "Xtro\thbs2, Xtro\comp, Xtro\thbs3, Xtro\thbs4, Xtro\thbs1, Xtro\nell2, Xtro\kcp" "Mmus\Nell1, Mmus\Thbs4, Mmus\Thbs2, Mmus\Thbs3, Mmus\Comp, Mmus\Thbs1, Mmus\Nell2" "Hsap\NELL1, Hsap\COMP, Hsap\THBS2, Hsap\THBS4, Hsap\THBS1, Hsap\NELL2, Hsap\THBS3" "viable,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval somatic muscle,embryonic/larval muscle system,tendon cell,muscle attachment site,lateral longitudinal muscle 1,ventral longitudinal muscle,dorsal oblique muscle,dorsal acute muscle" FBgn0085832 CR42205 - http://flybase.org/reports/FBgn0085832 non_protein_coding_gene - - - CR42205 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005290 mei-2185 meiotic 2185 http://flybase.org/reports/FBgn0005290 - gene - - - "2185, mei-2185" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0065680 l(2)SH0669 lethal (2) SH0669 http://flybase.org/reports/FBgn0065680 gene - - - "l(2)SH0669, l(2)SH2 0669" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016082 ynd yande http://flybase.org/reports/FBgn0016082 - gene - - - ynd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264699 CG43968 - http://flybase.org/reports/FBgn0264699 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43968, lincRNA.665" - CG43968 11-Aug-17 DroID_v2017_08 "Drer\adgrd2, Drer\adgre5b.3, Drer\LOC100538279, Drer\adgre10, Drer\fbn2a, Drer\adgrg2a, Drer\LOC100535070, Drer\adgrl2a, Drer\adgrg4a, Drer\adgrf3a, Drer\LOC101884341, Drer\LOC100537181, Drer\adgre14, Drer\adgrl4, Drer\adgrg1, Drer\adgrl1a, Drer\adgrg3, Drer\adgrf6, Drer\adgrl3.1, Drer\LOC101886975, Drer\fbn2b, Drer\adgrf11, Drer\adgrg6, Drer\adgrg11" - - "Xtro\adgrg1, Xtro\adgrv1, Xtro\adgrf1, Xtro\adgrf3, Xtro\adgre5, Xtro\adgrl1, Xtro\adgrd1" "Mmus\Adgrl1, Mmus\Adgrg3, Mmus\Adgrf4, Mmus\Adgre4, Mmus\Adgrf3, Mmus\Adgrg6, Mmus\Adgrg5, Mmus\Adgrd1, Mmus\Adgrl4, Mmus\Adgrf5, Mmus\Adgrl3, Mmus\Adgrl2, Mmus\Adgrg7, Mmus\Adgrf2, Mmus\Adgrg4, Mmus\Adgrg2, Mmus\Adgrg1, Mmus\Adgre5, Mmus\Adgre1, Mmus\Adgrf1" "Hsap\ADGRG6, Hsap\ADGRG7, Hsap\ADGRE5, Hsap\ADGRF3, Hsap\ADGRF5, Hsap\ADGRL2, Hsap\ADGRF4, Hsap\ADGRE1, Hsap\ADGRL1, Hsap\ADGRG1, Hsap\ADGRL3, Hsap\ADGRE2, Hsap\ADGRG3, Hsap\ADGRL4, Hsap\FBN3, Hsap\ADGRE3, Hsap\ADGRD1, Hsap\ADGRD2, Hsap\ADGRF1, Hsap\ADGRG2, Hsap\ADGRF2, Hsap\ADGRG5, Hsap\ADGRG4" FBgn0033300 CG14754 - http://flybase.org/reports/FBgn0033300 protein_coding_gene - - - CG14754 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC06489 K -0.116909718 0.354327169 -0.375000758 -0.203823896 0.742037203 1.679481032 FBgn0259464 EP-298 - http://flybase.org/reports/FBgn0259464 gene - - - EP-298 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0038871 CG3337 - http://flybase.org/reports/FBgn0038871 protein_coding_gene - - - "CG3337, mat1" IPR029063:S-adenosyl-L-methionine-dependent methyltransferase CG3337 11-Aug-17 DroID_v2017_08 "Drer\fam173b, Drer\fam173a, Drer\si:dkey-190g11.3" - Cele\Y39A1A.21 Xtro\fam173b "Mmus\Fam173a, Mmus\Fam173b" "Hsap\FAM173A, Hsap\FAM173B" viable FBgn0036695 Papst2 PAPS transporter 2 http://flybase.org/reports/FBgn0036695 protein_coding_gene 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity ; GO:0046964 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR013657 3'-phosphoadenosine 5'-phosphosulfate transport ; GO:0046963 | inferred from direct assay heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from mutant phenotype integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 Golgi cis cisterna ; GO:0000137 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "Papst2, CG7853, dPAPST2, PAPST2" IPR013657:UAA transporter CG7853 11-Aug-17 DroID_v2017_08 Drer\slc35b3 Scer\HUT1 Cele\pst-2 Xtro\slc35b3 Mmus\Slc35b3 "Hsap\SLC35B3, Hsap\SLC35B1" partially lethal - majority die FBgn0039954 CG17429 - http://flybase.org/reports/FBgn0039954 protein_coding_gene - - - "CG40065, CG17429" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028082 l(3)S085212 lethal (3) S085212 http://flybase.org/reports/FBgn0028082 gene - - - "0852/12, l(3)S085212" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044323 Cka Connector of kinase to AP-1 http://flybase.org/reports/FBgn0044323 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with bsk inferred from physical interaction with Jra inferred from physical interaction with kay inferred from physical interaction with hep positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of JNK cascade ; GO:0046330 | inferred from direct assay inferred from genetic interaction with bsk inferred from genetic interaction with Jra inferred from genetic interaction with kay inferred from genetic interaction with hep regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype JNK cascade ; GO:0007254 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "cka, CKA, CG7392, Dcka, l(2)05836, 5836, l(2)s1883, anon-WO0172774.179, anon-WO0172774.177, anon-WO0172774.175, anon-WO0172774.174, Cka" "IPR001680:WD40 repeat, IPR013258:Striatin, N-terminal, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like" CG7392 11-Aug-17 DroID_v2017_08 "Drer\strn4, Drer\strn3, Drer\strn" "Scer\FAR8, Scer\COP1" Cele\cash-1 "Xtro\strn, Xtro\strn3" "Mmus\Strn, Mmus\Strn4, Mmus\Strn3" "Hsap\STRN4, Hsap\STRN, Hsap\WDR64, Hsap\STRN3" "viable,fertile,lethal,recessive,fully,rescuable maternal effect,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,gravitaxis defective,visible" "imaginal disc,embryonic/first instar larval cuticle,dorsal,head,embryonic dorsal epidermis,germline clone,rescuable maternal effect,embryonic head,embryonic leading edge cell,maternal effect,tarsal segment,arista,third segment of antenna,wing,unguis,pulvillus" DRSC22858 I 0.384946579 -3.511340136 0.001923618 -0.032850192 0.413195443 -0.156517786 FBgn0053640 CG33640 - http://flybase.org/reports/FBgn0053640 protein_coding_gene enzyme activator activity ; GO:0008047 | inferred from electronic annotation with InterPro:IPR028996 molecular_function ; GO:0003674 | no biological data available ganglioside catabolic process ; GO:0006689 | inferred from electronic annotation with InterPro:IPR028996 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33640 "IPR028996:Ganglioside GM2 activator, IPR010512:Protein of unknown function DUF1091" CG33640 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060440 l(3)S124310b lethal (3) S124310b http://flybase.org/reports/FBgn0060440 gene - - - "1243/10, l(3)S124310b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029957 CG12155 - http://flybase.org/reports/FBgn0029957 protein_coding_gene - - - CG12155 IPR006578:MADF domain CG12155 11-Aug-17 DroID_v2017_08 - - - - Mmus\Hrct1 Hsap\HRCT1 viable FBgn0000505 dsx-c21C doublesex cognate 21C http://flybase.org/reports/FBgn0000505 - gene - - - "dsx-c21, dsx-c21C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259638 B1193 - http://flybase.org/reports/FBgn0259638 gene - - - B1193 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,submarginal cell,anterior crossvein,tarsal segment,unguis,arista" FBgn0040358 CG14625 - http://flybase.org/reports/FBgn0040358 protein_coding_gene - - - "EG:BACR42I17.8, CG14625" - CG14625 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0030289 GCS1 Glucosidase 1 http://flybase.org/reports/FBgn0030289 protein_coding_gene mannosyl-oligosaccharide glucosidase activity ; GO:0004573 | inferred from electronic annotation with InterPro:IPR004888 oligosaccharide metabolic process ; GO:0009311 | inferred from electronic annotation with InterPro:IPR004888 endomembrane system ; GO:0012505 | inferred from direct assay "CG1597, GCS1" "IPR008928:Six-hairpin glycosidase-like, IPR004888:Glycoside hydrolase family 63, IPR031335:Glycosyl hydrolase family 63, C-terminal, IPR031631:Glycosyl hydrolase family 63, N-terminal" CG1597 11-Aug-17 DroID_v2017_08 Drer\mogs "Scer\YMR196W, Scer\CWH41" "Cele\R03E9.2, Cele\mogs-1" Xtro\mogs Mmus\Mogs Hsap\MOGS "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039560 BOD1 Biorientation Defective 1 http://flybase.org/reports/FBgn0039560 protein_coding_gene - nonassociative learning ; GO:0046958 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype - "CG5514, BOD1, Bod1" IPR026955:Biorientation of chromosomes in cell division protein 1-like CG5514 11-Aug-17 DroID_v2017_08 "Drer\bod1l1, Drer\bod1" - - "Xtro\bod1, Xtro\bod1l1" "Mmus\Bod1, Mmus\Bod1l" "Hsap\BOD1, Hsap\BOD1L2, Hsap\BOD1L1" "viable,visible" trichogen cell FBgn0061120 l(3)S005029a lethal (3) S005029a http://flybase.org/reports/FBgn0061120 gene - - - "0050/29, l(3)S005029a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058302 CG40302 - http://flybase.org/reports/FBgn0058302 protein_coding_gene - - - CG40302 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002283 l(3)73Ah lethal (3) 73Ah http://flybase.org/reports/FBgn0002283 "FBgn0010783, FBgn0036644" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:10066 "l(3)02540, l(3)133.18, CG4195, l(3)73Ah, L(3)73Ah, I(3)73Ah" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR032443:RAWUL domain" CG4195 11-Aug-17 DroID_v2017_08 "Drer\si, Drer\pcgf6, Drer\bmi1a, Drer\bmi1b, Drer\pcgf1, Drer\pcgf5a, Drer\pcgf5b" - Cele\mig-32 "Xtro\pcgf2, Xtro\pcgf3, Xtro\bmi1, Xtro\pcgf6" "Mmus\Pcgf2, Mmus\Pcgf3, Mmus\Pcgf6, Mmus\Pcgf5, Mmus\Bmi1, Mmus\Pcgf1" "Hsap\PCGF2, Hsap\COMMD3-BMI1, Hsap\PCGF3, Hsap\PCGF6, Hsap\BMI1, Hsap\PCGF5, Hsap\PCGF1" " embryonic stage -- adult stage , oogenesis stage && adult stage | female , larval stage && adult stage " " ovary

, fat body

" "lethal,recessive,wild-type,viable,visible" "adult abdomen,trichogen cell,mesothoracic tergum" DRSC11359 E -0.242281382 -0.67886684 -0.102363826 -1.684949359 -0.870630189 0.441301766 FBgn0261614 CG42703 - http://flybase.org/reports/FBgn0261614 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42703 IPR029375:Protein of unknown function DUF4558 CG42703 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085358 Diedel3 Diedel 3 http://flybase.org/reports/FBgn0085358 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from sequence or structural similarity with Diedel "CG34329, CG14189, Diedel3, Diedel-3" IPR025061:Diedel CG34329 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267867 CR46155 - http://flybase.org/reports/FBgn0267867 pseudogene_attribute - - - CR46155 - CR46155 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265735 CR44542 - http://flybase.org/reports/FBgn0265735 non_protein_coding_gene - - - "CR44542, incRNA.489, lincRNA.489" - CR44542 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011902 tRNA:Lys-TTT-1-1 transfer RNA:Lysine-TTT 1-1 http://flybase.org/reports/FBgn0011902 "FBgn0003793, FBgn0011901, FBgn0051899, FBgn0060177" tRNA_gene AAA codon-amino acid adaptor activity ; GO:0033443 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033443 cytosol ; GO:0005829 | inferred by curator from GO:0033443 "lys-tRNA-5, AE002690.trna3-LysTTT, tRNA:K5, tRNA:K:TTT:AE002690, CR31899, tRNA:lys5:29A, chr2L.trna11-LysTTT, tRNA-Lys-TTT-1-1, tRNA:Lys-TTT-1-1, tRNA:K5:29A, AAA" - CR31899 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005545 l(3)72Dm lethal (3) 72Dm http://flybase.org/reports/FBgn0005545 - gene - - - l(3)72Dm - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034740 nsr novel spermatogenesis regulator http://flybase.org/reports/FBgn0034740 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 RNA binding ; GO:0003723 | inferred from sequence model sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype posttranscriptional regulation of gene expression ; GO:0010608 | inferred from mutant phenotype nuclear speck ; GO:0016607 | inferred from direct assay "cg3875, nsr, CG3875" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG3875 11-Aug-17 DroID_v2017_08 "Drer\qki2, Drer\khdrbs1a, Drer\khdrbs1b, Drer\qkib, Drer\khdrbs3, Drer\qkia, Drer\khdrbs2" Scer\MSL5 "Cele\gld-1, Cele\sfa-1, Cele\Y57G11C.36, Cele\B0280.11, Cele\asd-2, Cele\F54D1.1, Cele\K07H8.9" "Xtro\khdrbs1, Xtro\qki, Xtro\khdrbs3, Xtro\khdrbs2" "Mmus\Khdrbs1, Mmus\Khdrbs2, Mmus\Qk, Mmus\Khdrbs3, Mmus\Sf1" "Hsap\QKI, Hsap\KHDRBS3, Hsap\SF1, Hsap\KHDRBS2, Hsap\KHDRBS1" "male sterile,recessive" "cystic bulge,investment cone,waste bag,individualization stage spermatid,spermatid axoneme" FBgn0039115 CG10214 - http://flybase.org/reports/FBgn0039115 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 oligonucleotidase activity ; GO:0008946 | inferred from sequence or structural similarity with UniProtKB:Q9Y3B8 cellular response to starvation ; GO:0009267 | inferred from expression pattern mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9Y3B8 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9Y3B8 CG10214 "IPR012337:Ribonuclease H-like domain, IPR013520:Exonuclease, RNase T/DNA polymerase III" CG10214 11-Aug-17 DroID_v2017_08 Drer\smfn Scer\REX2 Cele\C08B6.8 Xtro\rexo2 Mmus\Rexo2 Hsap\REXO2 viable FBgn0040342 CG3706 - http://flybase.org/reports/FBgn0040342 protein_coding_gene - - - "EG:BAC7A4.20, ESTS:99F6T, EG:BACR7A4.20, CG3706" - CG3706 11-Aug-17 DroID_v2017_08 - - Cele\C05D2.8 - - - viable FBgn0060704 l(3)S071411b lethal (3) S071411b http://flybase.org/reports/FBgn0060704 gene - - - "0714/11, l(3)S071411b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0025491 l(3)82Db lethal (3) 82Db http://flybase.org/reports/FBgn0025491 - gene - - - l(3)82Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040496 CG17104 - http://flybase.org/reports/FBgn0040496 protein_coding_gene - - - "BEST:LD16579, CG17104" - CG17104 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051294 CG31294 - http://flybase.org/reports/FBgn0051294 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs25d10, NEST:bs15e12, BcDNA:AT21457, CG31294" "IPR013026:Tetratricopeptide repeat-containing domain, IPR011990:Tetratricopeptide-like helical domain, IPR019734:Tetratricopeptide repeat" CG31294 11-Aug-17 DroID_v2017_08 "Drer\tex11, Drer\zgc:123010, Drer\stip1, Drer\si:dkey-33c12.4, Drer\sgut1, Drer\tomm34, Drer\spag1a, Drer\dyx1c1, Drer\spag1b, Drer\ttc4, Drer\ttc12" "Scer\TOM71, Scer\STI1, Scer\CNS1, Scer\SGT2, Scer\TOM70, Scer\SWA2" Cele\C33H5.8 "Xtro\sugt1, Xtro\stip1" "Mmus\Ttc12, Mmus\Ttc4, Mmus\Tomm34, Mmus\Tex11, Mmus\Spag1, Mmus\Sugt1, Mmus\Dyx1c1, Mmus\Stip1" "Hsap\TOMM34, Hsap\TTC12, Hsap\TEX11, Hsap\STIP1, Hsap\TTC31, Hsap\SUGT1, Hsap\TTC28, Hsap\TTC4, Hsap\DYX1C1, Hsap\SPAG1" FBgn0020781 smoq small monoene quantities http://flybase.org/reports/FBgn0020781 - gene - pheromone metabolic process ; GO:0042810 | inferred from mutant phenotype - smoq - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065928 l(2)SH0141 lethal (2) SH0141 http://flybase.org/reports/FBgn0065928 gene - - - "l(2)SH0141, l(2)SH2 0141" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263532 mir-4962 mir-4962 stem loop http://flybase.org/reports/FBgn0263532 miRNA_gene - - - "mir-4962, dme-mir-4962, CR43517" - CR43517 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002146 l(2)K508 lethal (2) K508 http://flybase.org/reports/FBgn0002146 - gene - - - l(2)K508 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085655 CG41494 - http://flybase.org/reports/FBgn0085655 protein_coding_gene - - - CG41494 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083942 CG34106 - http://flybase.org/reports/FBgn0083942 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34106 - CG34106 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037716 CG8273 - http://flybase.org/reports/FBgn0037716 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR032922 double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity regulation of RNA splicing ; GO:0043484 | inferred from electronic annotation with InterPro:IPR032922 regulation of cell cycle ; GO:0051726 | inferred from electronic annotation with InterPro:IPR032922 - "cg8273, CG8273" "IPR000467:G-patch domain, IPR014720:Double-stranded RNA-binding domain, IPR032922:Protein SON" CG8273 11-Aug-17 DroID_v2017_08 Drer\gpatch2 Scer\SQS1 "Cele\Y55D9A.2, Cele\D1037.1" - "Mmus\Son, Mmus\Aggf1, Mmus\Gpatch2" "Hsap\AGGF1, Hsap\GPATCH2, Hsap\SON" viable FBgn0023075 l(1)19Cd lethal (1) 19Cd http://flybase.org/reports/FBgn0023075 - gene - - - "800D9, l(1)19Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037180 CG14452 - http://flybase.org/reports/FBgn0037180 protein_coding_gene - - - "BcDNA:RE59202, CG14452" - CG14452 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052127 tRNA:Leu-CAA-2-2 transfer RNA:Leucine-CAA 2-2 http://flybase.org/reports/FBgn0052127 tRNA_gene UUG codon-amino acid adaptor activity ; GO:0033404 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033404 cytosol ; GO:0005829 | inferred by curator from GO:0033404 "AE002602.trna19-LeuCAA, tRNA:L:CAA:AE002602, CR32127, chr3L.trna25-LeuCAA, tRNA-Leu-CAA-2-2, tRNA:Leu-CAA-2-2, tRNA:CR32127, UUG" - CR32127 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083940 RhoU RhoU http://flybase.org/reports/FBgn0083940 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with MGI:MGI:1916831" small GTPase mediated signal transduction ; GO:0007264 | inferred from sequence or structural similarity with MGI:MGI:1916831 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003578 cellular_component ; GO:0005575 | no biological data available "CG12094, CG12102, CG34104, RhoU" "IPR001806:Small GTPase superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR015943:WD40/YVTN repeat-like-containing domain, IPR003578:Small GTPase superfamily, Rho type, IPR005225:Small GTP-binding protein domain" CG34104 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-6b12.5, Drer\cdc42l2, Drer\rhocb, Drer\rnd1a, Drer\rac1l, Drer\rhoac, Drer\rhobtb2b, Drer\si:dkey-263f15.2, Drer\rhogc, Drer\rhof, Drer\rhoub, Drer\LOC100331257, Drer\cdc42l, Drer\rac1b, Drer\rhoaa, Drer\si:ch211-133l11.10, Drer\rnd2, Drer\rhoga, Drer\rac3b, Drer\cdc42, Drer\rhov, Drer\rnd3a, Drer\rhobtb1, Drer\rhoca, Drer\rhoh, Drer\rac1a, Drer\rhoq, Drer\rhogb, Drer\rhobtb2a, Drer\rnd3b, Drer\rac3a, Drer\rhoua, Drer\rnd1b, Drer\rhoj, Drer\rhoab" "Scer\RHO3, Scer\RHO4, Scer\CDC42, Scer\RHO1, Scer\RHO5, Scer\RHO2" Cele\chw-1 "Xtro\rhoa.2, Xtro\cdc42, Xtro\rhobtb3, Xtro\rhoa, Xtro\rhoc, Xtro\rhobtb1, Xtro\rac1, Xtro\rhobtb2, Xtro\rhou, Xtro\rhof, Xtro\rhob, Xtro\rnd3, Xtro\rhoj, Xtro\rhov, Xtro\rac2, Xtro\rnd1" "Mmus\Rnd2, Mmus\Rac2, Mmus\Rhod, Mmus\Rac1, Mmus\Rhov, Mmus\Cdc42, Mmus\Rnd3, Mmus\Rhof, Mmus\Rhoa, Mmus\Rhoh, Mmus\Rhoq, Mmus\Rhob, Mmus\Rhog, Mmus\Rhobtb1, Mmus\Rhoj, Mmus\Rhobtb3, Mmus\Rnd1, Mmus\Rac3, Mmus\Rhou, Mmus\4930544G11Rik, Mmus\Rhobtb2, Mmus\Rhoc" "Hsap\RAC1, Hsap\RND1, Hsap\RHOU, Hsap\RHOB, Hsap\RHOV, Hsap\RHOD, Hsap\RHOH, Hsap\RHOJ, Hsap\RAC3, Hsap\RHOQ, Hsap\RHOC, Hsap\RHOF, Hsap\RND3, Hsap\RHOBTB1, Hsap\RHOBTB3, Hsap\RAC2, Hsap\RND2, Hsap\RHOG, Hsap\CDC42, Hsap\RHOBTB2, Hsap\RHOA" viable DRSC25197 K -0.125687542 0.254871148 0.279029929 0.690131491 1.774257895 0.642517213 FBgn0062666 EP3135 EP3135 http://flybase.org/reports/FBgn0062666 gene - - - "EP(3)3135, EP3135" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065040 6BP 6BP http://flybase.org/reports/FBgn0065040 gene - - - "D6BP, 6BP" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040965 CR13130 - http://flybase.org/reports/FBgn0040965 non_protein_coding_gene - - - "CG13130, CR13130" - CR13130 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" DRSC02226 IE -1.845302701 -5.401974178 0.298412135 -4.333488201 -1.420584717 -1.326632042 FBgn0062631 Mab3 Monoclonal antibody 3 http://flybase.org/reports/FBgn0062631 gene - - - Mab3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085553 CG41012 - http://flybase.org/reports/FBgn0085553 protein_coding_gene - - - CG41012 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000367 cra crack http://flybase.org/reports/FBgn0000367 - gene molecular_function ; GO:0003674 | no biological data available head involution ; GO:0008258 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available cra - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive" embryonic head FBgn0082962 snoRNA:Psi28S-3385a snoRNA:Psi28S-3385a http://flybase.org/reports/FBgn0082962 snoRNA_gene - - - "snoRNA:Psi28S-3385a, psi28s-3385a, Psi 28S-3385a, CR34608" - CR34608 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001198 His2B Histone H2B http://flybase.org/reports/FBgn0001198 FBgn0039974 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000558, InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072" - nucleosome ; GO:0000786 | traceable author statement nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR000558 "H2B, HisC, H2b, His2b, dH2B, DmeH2b, H2[[B]], His2B, histone, his, dH2b" "IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3, IPR009072:Histone-fold" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263036 CG43331 - http://flybase.org/reports/FBgn0263036 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43331, CG12377" - CG43331 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266586 CR45111 - http://flybase.org/reports/FBgn0266586 non_protein_coding_gene - - - CR45111 - CR45111 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069177 mcl(2)Z3534 mcl(2)Z3534 http://flybase.org/reports/FBgn0069177 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z3534 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0264894 CG44085 - http://flybase.org/reports/FBgn0264894 protein_coding_gene MAP-kinase scaffold activity ; GO:0005078 | inferred from biological aspect of ancestor with PANTHER:PTN000492368 - - "CG44085, CG6043, CG6108" IPR015943:WD40/YVTN repeat-like-containing domain CG44085 11-Aug-17 DroID_v2017_08 - "Scer\SPH1, Scer\SPA2" - - - - FBgn0261444 CG3638 - http://flybase.org/reports/FBgn0261444 protein_coding_gene chloride channel activity ; GO:0005254 | inferred from sequence or structural similarity with UniProtKB:Q9C0H2 chloride channel activity ; GO:0005254 | inferred from sequence or structural similarity with HGNC:22222 mushroom body development ; GO:0016319 | inferred from mutant phenotype chloride transport ; GO:0006821 | inferred from sequence or structural similarity with HGNC:22222 phagocytosis ; GO:0006909 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q9C0H2 plasma membrane ; GO:0005886 | inferred from direct assay "CG3638, EG:33C11.3, BG00376, TTYH2" "IPR006990:Tweety, IPR015943:WD40/YVTN repeat-like-containing domain" CG3638 11-Aug-17 DroID_v2017_08 "Drer\ttyh2, Drer\ttyh1, Drer\ttyh2l, Drer\ttyh3b, Drer\ttyh3a" - Cele\ttyh-1 "Xtro\ttyh3, Xtro\ttyh2, Xtro\ttyh1" "Mmus\Ttyh1, Mmus\Ttyh3, Mmus\Ttyh2" "Hsap\TTYH2, Hsap\TTYH3, Hsap\TTYH1" DRSC18533 E -0.01778315 0.995944868 1.882617982 0.230868316 -0.491594347 -0.127829802 FBgn0038099 CG7091 - http://flybase.org/reports/FBgn0038099 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 CG7091 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG7091 11-Aug-17 DroID_v2017_08 - "Scer\TNA1, Scer\DAL5, Scer\YIL166C, Scer\THI73" "Cele\slc-17.5, Cele\F11A5.9, Cele\M117.1, Cele\slc-17.6, Cele\C39E9.7, Cele\Y19D10A.8, Cele\Y19D10A.4, Cele\C35A5.3, Cele\K08C7.1, Cele\F56A4.12, Cele\F59A1.13, Cele\C18H9.5, Cele\Y4C6B.3, Cele\C01B4.8, Cele\Y19D10A.11, Cele\W04C9.6, Cele\T22F3.10, Cele\Y51B9A.6, Cele\slc-17.3, Cele\F41C3.2, Cele\T28H11.8, Cele\Y4C6B.4, Cele\T19D12.9, Cele\T27D12.1, Cele\slc-17.9, Cele\F44E7.7, Cele\T22F3.7, Cele\Y19D10A.5, Cele\R10D12.1, Cele\T22F3.8, Cele\D1046.4, Cele\M162.5, Cele\cima-1, Cele\F10C2.7, Cele\H11E01.2, Cele\T22F3.11, Cele\T19D12.10, Cele\T01H3.3, Cele\slc-17.7, Cele\slc-17.8, Cele\K11G9.5, Cele\C01B4.7, Cele\slc-17.4, Cele\C18D1.2, Cele\Y15E3A.4, Cele\T02B11.6, Cele\F56A4.10" - Mmus\Slc37a1 Hsap\SLC37A1 "viable,fertile" FBgn0032719 CG17321 - http://flybase.org/reports/FBgn0032719 protein_coding_gene - - - CG17321 - CG17321 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263278 Fic Fic domain-containing protein http://flybase.org/reports/FBgn0263278 protein_coding_gene protein adenylyltransferase activity ; GO:0070733 | inferred from direct assay detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype histamine transport ; GO:0051608 | inferred from mutant phenotype protein adenylylation ; GO:0018117 | inferred from direct assay visual behavior ; GO:0007632 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "Fic, CG9523, l(2)k11101" "IPR003812:Fido domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain" CG9523 11-Aug-17 DroID_v2017_08 Drer\ficd - Cele\fic-1 Xtro\ficd Mmus\Ficd Hsap\FICD FBgn0046700 Penelope\ORF1 Penelope element ORF1 http://flybase.org/reports/FBgn0046700 transposable_element_gene - - - Penelope\ORF1 "IPR000305:GIY-YIG nuclease superfamily, IPR000477:Reverse transcriptase domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031611 FIG4 FIG4 phosphoinositide 5-phosphatase http://flybase.org/reports/FBgn0031611 protein_coding_gene phosphoric ester hydrolase activity ; GO:0042578 | inferred from electronic annotation with InterPro:IPR002013 - - "CG17840, FIG4, dFIG4, Fig4" IPR002013:SAC domain CG17840 11-Aug-17 DroID_v2017_08 Drer\fig4a Scer\FIG4 Cele\C34B7.2 Xtro\fig4 Mmus\Fig4 Hsap\FIG4 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039239 CG13641 - http://flybase.org/reports/FBgn0039239 protein_coding_gene - - - CG13641 - CG13641 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035719 tow target of wingless http://flybase.org/reports/FBgn0035719 protein_coding_gene - negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | inferred from genetic interaction with fz imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "tow, CG14821, Tow" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR027967:Protein of unknown function DUF4612" CG14821 11-Aug-17 DroID_v2017_08 Drer\zgc:55943 - Cele\R02E12.5 - Mmus\1700025G04Rik Hsap\C1orf21 "visible,viable,fertile" "wing vein L3,wing vein L4,1st posterior cell,wing,wing hair,supernumerary,microchaeta & adult thoraxap-md544,macrochaeta & adult thoraxap-md544,scutellum,wing blade,anterior wing margin,distal" DRSC23125 K -2.016290594 -0.300568405 FBgn0259316 EP-339 - http://flybase.org/reports/FBgn0259316 gene - - - EP-339 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0031708 CG7382 - http://flybase.org/reports/FBgn0031708 protein_coding_gene - mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from biological aspect of ancestor with PANTHER:PTN000315366 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000315366 mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from biological aspect of ancestor with PANTHER:PTN000315366 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000315366 CG7382 IPR013261:Mitochondrial import inner membrane translocase subunit Tim21 CG7382 11-Aug-17 DroID_v2017_08 Drer\si:dkey-118j18.1 Scer\TIM21 Cele\F56B3.11 Xtro\timm21 Mmus\Timm21 Hsap\TIMM21 FBgn0065309 l(2)SH1958 lethal (2) SH1958 http://flybase.org/reports/FBgn0065309 gene - - - "l(2)SH1958, l(2)SH2 1958" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020880 CG7179 - http://flybase.org/reports/FBgn0020880 - protein_coding_gene - synaptic target recognition ; GO:0008039 | inferred from mutant phenotype - "tld-like, CT22169, Opa, anon-28Cg, CG7179" "IPR000859:CUB domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR021587:Transcription activator LAG-3" CG7179 11-Aug-17 DroID_v2017_08 - - "Cele\clec-6, Cele\clec-10" - Mmus\Tnfaip6 Hsap\TNFAIP6 viable FBgn0260719 CR42546 - http://flybase.org/reports/FBgn0260719 pseudogene_attribute - - - CR42546 - CR42546 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037352 CG14673 - http://flybase.org/reports/FBgn0037352 protein_coding_gene - - - CG14673 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0053267 CG33267 - http://flybase.org/reports/FBgn0053267 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33267 - CG33267 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065583 l(2)SH0924 lethal (2) SH0924 http://flybase.org/reports/FBgn0065583 gene - - - "l(2)SH0924, l(2)SH2 0924" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027282 l(1)G0186 lethal (1) G0186 http://flybase.org/reports/FBgn0027282 - gene - - - l(1)G0186 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0020530 l(3)9C3 lethal (3) 9C3 http://flybase.org/reports/FBgn0020530 - gene - - - l(3)9C3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050424 CG30424 - http://flybase.org/reports/FBgn0050424 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG30424, mdcds_18556" IPR024810:Mab-21 domain CG30424 11-Aug-17 DroID_v2017_08 Drer\mb21d1 - - - Mmus\Mb21d1 Hsap\MB21D1 FBgn0003674 Tch Thin chaetae http://flybase.org/reports/FBgn0003674 - gene - - - Tch - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015861 anon-21Aa anon-21Aa http://flybase.org/reports/FBgn0015861 - gene - - - anon-21Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051538 CG31538 - http://flybase.org/reports/FBgn0051538 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs10d08, NEST:bs09e09, NEST:bs09g01, NEST:bs02h07, BcDNA:AT27831, BEST:GH11373, BEST:GH27336, BEST:LP11873, NEST:bs26g11, BEST:GH20014, CG31538" - CG31538 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary" FBgn0011936 tRNA:Asn-GTT-1-3 transfer RNA:Asparagine-GTT 1-3 http://flybase.org/reports/FBgn0011936 "FBgn0003759, FBgn0053973, FBgn0060131" tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "CR33973, Asn6, Asn-tRNA-6, AE002769.trna7-AsnGTT, tRNA:N:GTT:AE002769-c, tRNA:asn5:42Af, chr2R.trna98-AsnGTT, tRNA-Asn-GTT-1-3, tRNA:Asn-GTT-1-3, tRNA:N5:42Af, AAC" - CR33973 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040271 Sulf1 Sulfated http://flybase.org/reports/FBgn0040271 protein_coding_gene N-acetylglucosamine-6-sulfatase activity ; GO:0008449 | inferred from mutant phenotype positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype heparin metabolic process ; GO:0030202 | inferred from genetic interaction with Hs6st negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Sulf1 negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "Sulf1, CG6725, Neu5, DSulf, Dsulf1, sulf1, DSulf1" "IPR000917:Sulfatase, N-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site, IPR024609:Extracellular sulfatase, C-terminal" CG6725 11-Aug-17 DroID_v2017_08 "Drer\sulf1, Drer\gnsb, Drer\arsk, Drer\sulf2a, Drer\gnsa, Drer\sulf2b" - Cele\sul-1 "Xtro\sulf2, Xtro\arsk, Xtro\sulf1, Xtro\gns" "Mmus\Arsk, Mmus\Gns, Mmus\Sulf2, Mmus\Sulf1" "Hsap\SULF2, Hsap\ARSK, Hsap\GNS, Hsap\SULF1" embryonic stage | stage 5 ventral neurogenic region | restricted

"visible,viable,fertile,somatic clone,lethal,partially lethal - majority die,some die during pupal stage" "anterior crossvein,wing,eye,wing margin,mechanosensory chaeta,supernumerary,taste bristle,1st posterior cell,somatic clone,anterior wing margin,wing margin bristle,external sensory organ precursor cell,wing blade,wing vein L2,imaginal tracheoblast,posterior crossvein,wing vein L4,wing vein L5,trichogen cell,mesothoracic tergum" FBgn0005274 l(3)SG94 lethal (3) SG94 http://flybase.org/reports/FBgn0005274 - gene - - - l(3)SG94 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0015468 l(2)44Fc lethal (2) 44Fc http://flybase.org/reports/FBgn0015468 - gene - - - l(2)44Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0028614 l(2)W11 lethal (2) W11 http://flybase.org/reports/FBgn0028614 gene - - - "l(2R)W11, l(2)W11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267027 CR45471 - http://flybase.org/reports/FBgn0267027 non_protein_coding_gene - - - CR45471 - CR45471 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036493 CG7255 - http://flybase.org/reports/FBgn0036493 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002293 CG7255 "IPR002293:Amino acid/polyamine transporter I, IPR029485:Cationic amino acid transporter, C-terminal" CG7255 11-Aug-17 DroID_v2017_08 "Drer\slc7a3a, Drer\slc7a2, Drer\slc7a14a, Drer\zgc:175280, Drer\slc7a14b, Drer\slc7a1, Drer\zgc:63694, Drer\slc7a3b, Drer\slc7a4" "Scer\MMP1, Scer\LYP1, Scer\SSY1, Scer\PUT4, Scer\ALP1, Scer\DIP5, Scer\BAP3, Scer\CAN1, Scer\GAP1, Scer\AGP2, Scer\HIP1, Scer\SAM3, Scer\TAT2, Scer\AGP1, Scer\AGP3, Scer\GNP1, Scer\TAT1, Scer\BAP2" "Cele\Y53F4B.12, Cele\C50D2.2, Cele\B0454.6, Cele\F23F1.6" "Xtro\slc7a2.1, Xtro\slc7a1, Xtro\slc7a14, Xtro\slc7a3, Xtro\slc7a2.2, Xtro\slc7a4" "Mmus\Slc7a4, Mmus\AU018091, Mmus\Slc7a3, Mmus\Slc7a1, Mmus\Slc7a2, Mmus\Slc7a14" "Hsap\SLC7A2, Hsap\SLC7A1, Hsap\SLC7A14, Hsap\SLC7A3, Hsap\SLC7A4" "viable,fertile" DRSC10790 K 0.89798475 0.95138133 0.454476163 0.181321083 -1.908011368 0.45009654 FBgn0038240 CG14851 - http://flybase.org/reports/FBgn0038240 protein_coding_gene - - - CG14851 - CG14851 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033271 CG8708 - http://flybase.org/reports/FBgn0033271 protein_coding_gene "beta-1,3-galactosyltransferase activity ; GO:0048531 | inferred from direct assay glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 protein glycosylation ; GO:0006486 | inferred from direct assay" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 Golgi medial cisterna ; GO:0005797 | inferred from direct assay "anon-WO0144478.10, anon-WO0140519.114, CG8708, dC1GalT2" "IPR026842:C1GALT1, IPR015943:WD40/YVTN repeat-like-containing domain, IPR003378:Fringe-like" CG8708 11-Aug-17 DroID_v2017_08 "Drer\c1galt1b, Drer\si:dkey-202e17.1, Drer\LOC564281, Drer\c1galt1c1, Drer\c1galt1a" - "Cele\Y38C1AB.1, Cele\C16D9.6, Cele\W09D10.5, Cele\F37A4.3, Cele\T09E11.12, Cele\E03H4.3, Cele\C38H2.2, Cele\Y38C1AB.5, Cele\F56H6.1, Cele\C17A2.3, Cele\bus-4, Cele\C02H6.1" "Xtro\LOC100496837, Xtro\LOC100485879, Xtro\c1galt1, Xtro\LOC100486030" "Mmus\C1galt1, Mmus\C1galt1c1" "Hsap\C1GALT1C1, Hsap\C1GALT1" "viable,fertile" FBgn0086558 Ubi-p5E Ubiquitin-5E http://flybase.org/reports/FBgn0086558 protein_coding_gene protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000003962 cellular protein modification process ; GO:0006464 | inferred from sequence or structural similarity ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000003962 microtubule associated complex ; GO:0005875 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay "CG18282, Ubi-p5E, Ubiq, Ub, CG32744, CR32744, DmUbi-p5E, UB, Ubi" "IPR000626:Ubiquitin domain, IPR019954:Ubiquitin conserved site, IPR019956:Ubiquitin, IPR029071:Ubiquitin-related domain" CG32744 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-202a12.4, Drer\faua, Drer\zgc:56596, Drer\ubc, Drer\faub, Drer\ubb, Drer\uba52, Drer\isg15, Drer\zfand4" Scer\UBI4 "Cele\C16C8.4, Cele\ubq-2, Cele\F14D2.11, Cele\ubq-1, Cele\F52C6.2" "Xtro\fau, Xtro\ubc, Xtro\zfand4, Xtro\ubl4a" "Mmus\Ubl4a, Mmus\Zfand4, Mmus\Isg15, Mmus\Oas1g, Mmus\Oas3, Mmus\Oasl2, Mmus\Ubl4b, Mmus\Oasl1, Mmus\Oas1a, Mmus\Fau, Mmus\Ubb, Mmus\Ubd, Mmus\Uba52, Mmus\Ubc, Mmus\Oas2" "Hsap\UBL4B, Hsap\OAS3, Hsap\ZFAND4, Hsap\UBD, Hsap\OAS1, Hsap\UBB, Hsap\OAS2, Hsap\ISG15, Hsap\UBA52, Hsap\UBL4A, Hsap\OASL, Hsap\UBC" viable FBgn0013694 mt:tRNA:Gly-TCC mitochondrial transfer RNA:Glycine-TCC http://flybase.org/reports/FBgn0013694 FBgn0002867 tRNA_gene - - - "CR34075, tRNA-Gly, mtdbD00006301, tRNA[Gly], mt:tRNA:Gly-TCC, mt:tRNA:G, mt:tRNA[Gly]" - CR34075 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038795 CG4335 - http://flybase.org/reports/FBgn0038795 protein_coding_gene L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR012776 trimethyllysine dioxygenase activity ; GO:0050353 | inferred from electronic annotation with InterPro:IPR012776 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR012776 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003819, InterPro:IPR012776 carnitine biosynthetic process ; GO:0045329 | inferred from electronic annotation with InterPro:IPR012776" - CG4335 "IPR003819:TauD/TfdA-like domain, IPR012776:Trimethyllysine dioxygenase, IPR010376:Domain of unknown function DUF971" CG4335 11-Aug-17 DroID_v2017_08 "Drer\tmlhe, Drer\bbox1" Scer\AIM17 "Cele\gbh-2, Cele\gbh-1" "Xtro\bbox1, Xtro\tmlhe" "Mmus\Bbox1, Mmus\Tmlhe" "Hsap\TMLHE, Hsap\BBOX1" viable FBgn0004594 Eig71Eg Ecdysone-induced gene 71Eg http://flybase.org/reports/FBgn0004594 - protein_coding_gene - defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 extracellular region ; GO:0005576 | inferred from sequence model "L71, L71-6, VI, gene VI, gene-VI, CG7336, Eig71Eg, eig71Eg" IPR003475:Insect protein of unknown function CG7336 11-Aug-17 DroID_v2017_08 - - Cele\W08F4.10 - - - viable FBgn0086294 GS14505 - http://flybase.org/reports/FBgn0086294 gene - - - "GS14505, 14505" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002758 mit(1)8 mitotic 8 http://flybase.org/reports/FBgn0002758 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0035861 CG7213 - http://flybase.org/reports/FBgn0035861 protein_coding_gene - - - CG7213 - CG7213 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0037359 MED27 Mediator complex subunit 27 http://flybase.org/reports/FBgn0037359 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity RNA polymerase II transcription cofactor activity ; GO:0001104 | contributes_to inferred by curator from GO:0016592 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype regulation of cellular respiration ; GO:0043457 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred by curator from GO:0016592 regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype mediator complex ; GO:0016592 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from sequence or structural similarity "Med27, Trap37, CRSP34, dCRSP34, dTRAP37, CG1245, MED27, dCrsp34, med27" "IPR021627:Mediator complex, subunit Med27" CG1245 11-Aug-17 DroID_v2017_08 Drer\med27 - Cele\R09F10.3 Xtro\med27 Mmus\Med27 Hsap\MED27 viable DRSC12205 K -1.258498246 0.255669867 -1.286068482 -0.58532536 1.624719547 0.663344617 FBgn0259977 Tdc1 Tyrosine decarboxylase 1 http://flybase.org/reports/FBgn0259977 protein_coding_gene "carboxy-lyase activity ; GO:0016831 | inferred from electronic annotation with InterPro:IPR002129, InterPro:IPR010977, InterPro:IPR021115 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 tyrosine decarboxylase activity ; GO:0004837 | inferred from sequence or structural similarity" cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010977 behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype - "dTdc1, CG30445, CG3686, Tdc1, tdc1, tdc" "IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR010977:Aromatic-L-amino-acid decarboxylase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase, IPR021115:Pyridoxal-phosphate binding site" CG30445 11-Aug-17 DroID_v2017_08 "Drer\ddc, Drer\hdc" - "Cele\tdc-1, Cele\basl-1, Cele\hdl-1, Cele\bas-1" "Xtro\hdc, Xtro\ddc" "Mmus\Ddc, Mmus\Hdc" "Hsap\HDC, Hsap\DDC" FBgn0082362 HM12 HM12 http://flybase.org/reports/FBgn0082362 gene - - - HM12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259843 Su(Ste):CR42412 Su(Ste):CR42412 http://flybase.org/reports/FBgn0259843 non_protein_coding_gene - - - "Su(Ste):CR42412, CR42412" - CR42412 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014293 l(3)64Bd lethal (3) 64Bd http://flybase.org/reports/FBgn0014293 - gene - - - l(3)64Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261015 Pif1A PFTAIRE-interacting factor 1A http://flybase.org/reports/FBgn0261015 protein_coding_gene - - - "Pif1A, CG33719/CG33720, CG42599, PIF-1A, CG11773, CG32940, CG9808, CG11774, BcDNA:GH12504, Pif1, CG33719, CG11776, DM22, IP06413p" "IPR029681:Coiled-coil domain-containing protein 157, IPR015866:Serine-tRNA synthetase, type1, N-terminal, IPR031994:Janus kinase and microtubule-interacting protein, C-terminal domain" CG42599 11-Aug-17 DroID_v2017_08 "Drer\akap9, Drer\ccdc157" - "Cele\tag-241, Cele\hcp-2" - Mmus\Ccdc157 Hsap\CCDC157 DRSC14142 I -1.639487553 0.29632076 -0.175923619 -0.760434039 0.773471813 -0.742831016 FBgn0031031 CG14218 - http://flybase.org/reports/FBgn0031031 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues - - "SPH211, CG14218" - CG14218 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19575 K -0.939859044 0.191055312 0.430723485 0.000445834 -0.104857886 1.654702547 FBgn0259940 ttd3 TRPL translocation defect 3 http://flybase.org/reports/FBgn0259940 protein_coding_gene - - - ttd3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030960 Atg101 Autophagy-related 101 http://flybase.org/reports/FBgn0030960 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from physical interaction with Atg101 protein domain specific binding ; GO:0019904 | inferred from physical interaction with Atg13 protein kinase binding ; GO:0019901 | inferred from physical interaction with Atg1 autophagy ; GO:0006914 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000329035 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype positive regulation of macroautophagy ; GO:0016239 | inferred from mutant phenotype pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN000329035 ATG1/ULK1 kinase complex ; GO:1990316 | inferred from direct assay "Atg101, CG7053" IPR012445:Autophagy-related protein 101 CG7053 11-Aug-17 DroID_v2017_08 "Drer\atg101, Drer\sgk494a, Drer\sgk494b" - "Cele\F31E3.2, Cele\epg-9" Xtro\atg101 "Mmus\Atg101, Mmus\BC030499" "Hsap\ATG101, Hsap\SGK494" viable FBgn0026207 mbo members only http://flybase.org/reports/FBgn0026207 "FBgn0010853, FBgn0023005, FBgn0038075, FBgn0062136" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9TVM2 inferred from physical interaction with UniProtKB:Q9W1X4 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W1A4 chromatin binding ; GO:0003682 | inferred from direct assay transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000327285 "protein import into nucleus ; GO:0006606 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | traceable author statement open tracheal system development ; GO:0007424 | traceable author statement antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype ribosomal large subunit export from nucleus ; GO:0000055 | inferred from biological aspect of ancestor with PANTHER:PTN000327285 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000327285 negative regulation of protein export from nucleus ; GO:0046826 | inferred from mutant phenotype ribosomal small subunit export from nucleus ; GO:0000056 | inferred from biological aspect of ancestor with PANTHER:PTN000327285 neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay inferred from mutant phenotype nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with UniProtKB:Q99567 "Dnup 88, dNup88, Dnup88, DNup88, Nup88, l(3)05043, l(3)S146507, 1465/7, 1465/07, CG6819, anon-WO0118547.263, mbo, Mbo, nup88" "IPR019321:Nucleoporin Nup88, IPR015943:WD40/YVTN repeat-like-containing domain" CG6819 11-Aug-17 DroID_v2017_08 Drer\nup88 Scer\NUP82 - Xtro\nup88 Mmus\Nup88 Hsap\NUP88 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,wild-type,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible" "embryonic/larval dorsal branch,embryonic/larval dorsal anastomosis,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0265142 Ir56e Ionotropic receptor 56e http://flybase.org/reports/FBgn0265142 pseudogene_attribute - - - "Ir56e, DmelIR56e, CR44211" - CR44211 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263893 l(3)H67 - http://flybase.org/reports/FBgn0263893 gene - - - l(3)H67 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0028415 Met75Cb Met75Cb http://flybase.org/reports/FBgn0028415 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "bs14h01.y1, CG18064, Met75Cb" - CG18064 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002291 l(3)80Fb lethal (3) 80Fb http://flybase.org/reports/FBgn0002291 - gene - - - "l7, l(3)Lh7, l(3)80Fb, 80Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030645 CG6308 - http://flybase.org/reports/FBgn0030645 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG6308, Alg14, dAlg14" IPR013969:Oligosaccharide biosynthesis protein Alg14-like CG6308 11-Aug-17 DroID_v2017_08 Drer\alg14 Scer\ALG14 Cele\algn-14 Xtro\alg14 Mmus\Alg14 Hsap\ALG14 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0034383 CG17821 - http://flybase.org/reports/FBgn0034383 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available CG17821 IPR002076:ELO family CG17821 11-Aug-17 DroID_v2017_08 "Drer\elovl7b, Drer\elovl8b, Drer\elovl2, Drer\zgc:101858, Drer\elovl5, Drer\elovl4b, Drer\elovl4a, Drer\hsd17b8, Drer\elovl1a, Drer\elovl8a, Drer\dhrs7, Drer\elovl1b, Drer\elovl7a" "Scer\ELO3, Scer\ELO1, Scer\ELO2" "Cele\C06E4.3, Cele\F28H7.2, Cele\dhs-14, Cele\dhs-11, Cele\Y47G6A.22, Cele\Y47G6A.21, Cele\dhs-25, Cele\F26D2.15, Cele\F25D1.5, Cele\elo-9, Cele\ZK829.1" "Xtro\elovl5, Xtro\dhrs7, Xtro\elovl1, Xtro\hsd17b8, Xtro\cbr4, Xtro\MGC79752, Xtro\elovl2, Xtro\elovl7" "Mmus\Elovl7, Mmus\Elovl5, Mmus\Elovl3, Mmus\Elovl2, Mmus\H2-Ke6, Mmus\Cbr4, Mmus\Dhrs7, Mmus\Elovl1, Mmus\Elovl4" "Hsap\ELOVL4, Hsap\ELOVL5, Hsap\DHRS7, Hsap\ELOVL2, Hsap\CBR4, Hsap\ELOVL3, Hsap\HSD17B8, Hsap\ELOVL7, Hsap\ELOVL1" viable FBgn0259290 C386 - http://flybase.org/reports/FBgn0259290 gene - - - C386 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing hair FBgn0061505 l(2)24Ae lethal (2) 24Ae http://flybase.org/reports/FBgn0061505 gene - - - l(2)24Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001652 l(1)ds4 lethal (1) discs small 4 http://flybase.org/reports/FBgn0001652 - gene - - - "l(1)d.sml.-4, l(1)ds4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264550 CR43929 - http://flybase.org/reports/FBgn0264550 non_protein_coding_gene - - - CR43929 - CR43929 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260802 EP2-760 - http://flybase.org/reports/FBgn0260802 gene - - - EP2-760 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036824 CG3902 - http://flybase.org/reports/FBgn0036824 protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091, InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786" cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CT12987, CG18168, CG3902, CG 3902, GH07925p" "IPR006089:Acyl-CoA dehydrogenase, conserved site, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal" CG3902 11-Aug-17 DroID_v2017_08 "Drer\acads, Drer\acadm, Drer\acadvl, Drer\acad8, Drer\zgc:85777, Drer\acad9, Drer\acadsb" - "Cele\acdh-4, Cele\acdh-9, Cele\acdh-2, Cele\acdh-3, Cele\acdh-1, Cele\acdh-7, Cele\acdh-8" "Xtro\acadm, Xtro\acadsb, Xtro\acad9, Xtro\MGC147631, Xtro\acad8, Xtro\ivd, Xtro\acads" "Mmus\Acadm, Mmus\Acadvl, Mmus\Acads, Mmus\Acad8, Mmus\Ivd, Mmus\Acad9, Mmus\Acadsb" "Hsap\ACADS, Hsap\ACADSB, Hsap\IVD, Hsap\ACADM, Hsap\ACADVL, Hsap\ACAD8, Hsap\ACAD9" FBgn0028586 l(?)H81 lethal (?) H81 http://flybase.org/reports/FBgn0028586 gene - - - l(?)H81 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032770 CG13086 - http://flybase.org/reports/FBgn0032770 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - CG13086 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG13086 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0050101 CG30101 - http://flybase.org/reports/FBgn0050101 protein_coding_gene - - - "CG15901, CG6564, CG30101, FBgn0050101, vajk-4" - CG30101 11-Aug-17 DroID_v2017_08 Drer\si:ch73-366l1.5 - Cele\T26C11.2 - Mmus\Ggn "Hsap\GGN, Hsap\TPRX1" "viable,fertile" FBgn0010650 l(2)08685 lethal (2) 08685 http://flybase.org/reports/FBgn0010650 - gene - - - l(2)08685 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262987 CG43295 - http://flybase.org/reports/FBgn0262987 protein_coding_gene - - - CG43295 IPR032739:MRN complex-interacting protein CG43295 11-Aug-17 DroID_v2017_08 Drer\zgc:123335 - - - Mmus\Mrnip Hsap\MRNIP FBgn0013740 wako walkabout http://flybase.org/reports/FBgn0013740 - gene - - - wako - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,neuroanatomy defective" FBgn0029594 CG14806 - http://flybase.org/reports/FBgn0029594 protein_coding_gene - positive regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043280 | inferred from biological aspect of ancestor with PANTHER:PTN001579212 intrinsic apoptotic signaling pathway ; GO:0097193 | inferred from biological aspect of ancestor with PANTHER:PTN001579212 positive regulation of release of cytochrome c from mitochondria ; GO:0090200 | inferred from biological aspect of ancestor with PANTHER:PTN001579212 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001579212 "CG14806, Apop1" IPR018796:Uncharacterised protein family UPF0671 CG14806 11-Aug-17 DroID_v2017_08 "Drer\klc1a, Drer\apopt1" - Cele\Y39B6A.34 Xtro\klc1 Mmus\Apopt1 Hsap\APOPT1 "immune response defective,viable" FBgn0264943 CR44112 - http://flybase.org/reports/FBgn0264943 non_protein_coding_gene - - - CR44112 - CR44112 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022193 l(2)k05103 lethal (2) k05103 http://flybase.org/reports/FBgn0022193 - gene - - - l(2)k05103 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014295 l(3)64Bf lethal (3) 64Bf http://flybase.org/reports/FBgn0014295 - gene - - - l(3)64Bf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000355 Cp15 Chorion protein 15 http://flybase.org/reports/FBgn0000355 - protein_coding_gene - multicellular organism development ; GO:0007275 | inferred from electronic annotation with InterPro:IPR005649 chorion ; GO:0042600 | inferred from electronic annotation with InterPro:IPR005649 "Cp15, s-15, s15, Dms15, S15, cp15, C.s15, s15-1, Cs15, E6, CG6519, melcp15" IPR005649:Chorion 2 CG6519 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage | stage S8-10 , adult stage | female , oogenesis stage | stage S13-14 " adult stage | female " ovary

{ v mus101K451 } , ovary

, ovary

{ 0 swa6 } , ovary

{ v fs(1)A1059K1 } " viable FBgn0033919 CG8547 - http://flybase.org/reports/FBgn0033919 protein_coding_gene - - - CG8547 - CG8547 11-Aug-17 DroID_v2017_08 - - Cele\pqn-22 - - - partially lethal - majority die FBgn0033521 CG12896 - http://flybase.org/reports/FBgn0033521 protein_coding_gene peroxiredoxin activity ; GO:0051920 | inferred from electronic annotation with InterPro:IPR019479 peroxidase activity ; GO:0004601 | inferred from sequence or structural similarity with MGI:MGI:894320 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 response to oxidative stress ; GO:0006979 | inferred from sequence or structural similarity with HGNC:16753 mesoderm development ; GO:0007498 | inferred from expression pattern" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:16753 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:16753 "BEST:LD11278, CG12896, RE05501p, RH54193" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR024706:Peroxiredoxin, AhpC-type, IPR013766:Thioredoxin domain" CG12896 11-Aug-17 DroID_v2017_08 "Drer\prdx1, Drer\prdx4, Drer\prdx6, Drer\prdx2, Drer\prdx3" "Scer\TSA1, Scer\TSA2, Scer\PRX1" "Cele\prdx-2, Cele\prdx-3, Cele\prdx-6" Xtro\prdx6 "Mmus\Prdx4, Mmus\Prdx6, Mmus\Prdx6b, Mmus\Prdx3, Mmus\Prdx1, Mmus\Prdx2" "Hsap\PRDX1, Hsap\PRDX2, Hsap\PRDX6, Hsap\PRDX4, Hsap\PRDX3" FBgn0036331 CG14117 - http://flybase.org/reports/FBgn0036331 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE44251, CG14117" - CG14117 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0260275 GSd499 - http://flybase.org/reports/FBgn0260275 gene - - - GSd499 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013592 l(3)A164.1M3 lethal (3) A164.1M3 http://flybase.org/reports/FBgn0013592 - gene - - - l(3)A164.1M3 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0039205 CG13623 - http://flybase.org/reports/FBgn0039205 protein_coding_gene "structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR016092 iron ion binding ; GO:0005506 | inferred from biological aspect of ancestor with PANTHER:PTN000008068 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from biological aspect of ancestor with PANTHER:PTN000008068 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from biological aspect of ancestor with PANTHER:PTN000008068" protein maturation by iron-sulfur cluster transfer ; GO:0097428 | inferred from electronic annotation with InterPro:IPR016092 iron-sulfur cluster assembly ; GO:0016226 | inferred from biological aspect of ancestor with PANTHER:PTN000008068 protein maturation ; GO:0051604 | inferred from biological aspect of ancestor with PANTHER:PTN000008068 lateral inhibition ; GO:0046331 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000008071 "CG13623, BcDNA:GH27470" "IPR000361:FeS cluster biogenesis, IPR016092:FeS cluster insertion protein" CG13623 11-Aug-17 DroID_v2017_08 Drer\isca2 Scer\ISA2 Cele\Y54G11A.9 Xtro\isca2 Mmus\Isca2 Hsap\ISCA2 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,trichogen cell" FBgn0266573 tRNA:Thr-TGT-2-3 transfer RNA:Threonine-TGT 2-3 http://flybase.org/reports/FBgn0266573 tRNA_gene ACA codon-amino acid adaptor activity ; GO:0033439 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033439 cytosol ; GO:0005829 | inferred by curator from GO:0033439 "CR45106, CR30260, tRNA:CR30260, tRNA:T3:47F, tRNA:T:TGT:AE002787-d, tRNA:thr3:47F, tRNA[[Thr]], tRNA[Thr][[3]], AE002787.trna33-ThrTGT, chr2R.trna15-ThrTGT, tRNA-Thr-TGT-2-3, tRNA:Thr-TGT-2-3, tRNA:CR45106, ACA" - CR45106 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044011 Spn43Ad Serpin 43Ad http://flybase.org/reports/FBgn0044011 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues - extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG1859, Spn43Ad" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG1859 11-Aug-17 DroID_v2017_08 "Drer\serpinb1l1, Drer\serpine3, Drer\serpinc1, Drer\serpinb1, Drer\serpinb1l4, Drer\serpinh2, Drer\serpinh1a, Drer\serpinh1b, Drer\serpina10a, Drer\zgc:173729, Drer\serpinb1l3, Drer\si:ch1073-416d2.3, Drer\serpine2, Drer\serpine1, Drer\serpinb1l2" - "Cele\srp-6, Cele\srp-3, Cele\srp-2, Cele\srp-1" - "Mmus\Serpinb6d, Mmus\Serpinb13, Mmus\Serpinc1, Mmus\Serpinb6e, Mmus\Serpinb11, Mmus\Serpinb6a, Mmus\Serpine3, Mmus\Serpinb10, Mmus\Serpina10, Mmus\Serpinh1, Mmus\Serpinb8, Mmus\Serpinb12, Mmus\Serpinb9d, Mmus\Serpinb9f, Mmus\Serpinb6b, Mmus\Serpinb9g, Mmus\Serpinb3c, Mmus\Gm11397, Mmus\Serpinb1c, Mmus\Serpinb1b, Mmus\Serpinb6c, Mmus\Serpine2, Mmus\Serpinb9, Mmus\Serpinb2, Mmus\Serpinb9e, Mmus\Serpine1, Mmus\Serpinb3b, Mmus\Serpinb9c, Mmus\Serpinb3a, Mmus\Serpinb3d, Mmus\Serping1, Mmus\Serpinb9b, Mmus\Serpinb5, Mmus\Serpinb1a" "Hsap\SERPINB5, Hsap\SERPINB2, Hsap\SERPINB13, Hsap\SERPINB4, Hsap\SERPINB10, Hsap\SERPING1, Hsap\SERPINB9, Hsap\SERPINE1, Hsap\SERPINE2, Hsap\SERPINC1, Hsap\SERPINB3, Hsap\SERPINB8, Hsap\HMSD, Hsap\SERPINB11, Hsap\SERPINE3, Hsap\SERPINH1, Hsap\SERPINB6, Hsap\SERPINB12, Hsap\SERPINB1, Hsap\SERPINA10" viable FBgn0058108 CG40108 - http://flybase.org/reports/FBgn0058108 protein_coding_gene - - - CG40108 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028075 l(3)S088205 lethal (3) S088205 http://flybase.org/reports/FBgn0028075 gene - - - "0882/05, l(3)S088205" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033706 Vha36-2 Vacuolar H[+] ATPase 36kD subunit 2 http://flybase.org/reports/FBgn0033706 protein_coding_gene "ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from electronic annotation with InterPro:IPR002699 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033176" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033176 proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity with Vha36-1 "vha36-2, CG13167, Vha36-2" "IPR002699:ATPase, V1 complex, subunit D" CG13167 11-Aug-17 DroID_v2017_08 Drer\atp6v1d Scer\VMA8 Cele\vha-14 Xtro\atp6v1d Mmus\Atp6v1d Hsap\ATP6V1D "viable,visible" mesothoracic tergum DRSC06294 K 0.107204398 -0.031677463 -0.004433578 0.707520991 -1.642916985 -0.393137924 FBgn0260463 Unc-115b Uncoordinated 115b http://flybase.org/reports/FBgn0260463 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR003128 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 cytoskeleton organization ; GO:0007010 | inferred from electronic annotation with InterPro:IPR003128 nucleoplasm ; GO:0005654 | inferred from direct assay "CG9489, CG31332, anon-WO0140519.9, unc-115, Unc-115b" "IPR001781:Zinc finger, LIM-type, IPR003128:Villin headpiece" CG31332 11-Aug-17 DroID_v2017_08 "Drer\ablim1a, Drer\ablim3, Drer\ablim2, Drer\ablim1b, Drer\dmtn" - Cele\unc-115 "Xtro\ablim3, Xtro\ablim2, Xtro\dmtn" "Mmus\Dmtn, Mmus\Ablim2, Mmus\Ablim1, Mmus\Ablim3" "Hsap\DMTN, Hsap\ABLIM2, Hsap\ABLIM1, Hsap\ABLIM3" FBgn0023094 cyc cycle http://flybase.org/reports/FBgn0023094 "FBgn0024953, FBgn0025108" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001067 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:O61735 protein heterodimerization activity ; GO:0046982 | non-traceable author statement RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from physical interaction with Clk DNA binding ; GO:0003677 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Clk" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001067, InterPro:IPR013767 regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | non-traceable author statement eclosion rhythm ; GO:0008062 | traceable author statement rhythmic behavior ; GO:0007622 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement behavioral response to cocaine ; GO:0048148 | traceable author statement circadian rhythm ; GO:0007623 | non-traceable author statement circadian regulation of gene expression ; GO:0032922 | inferred from mutant phenotype regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | traceable author statement locomotor rhythm ; GO:0045475 | traceable author statement circadian rhythm ; GO:0007623 | traceable author statement behavioral response to cocaine ; GO:0048148 | non-traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | non-traceable author statement response to starvation ; GO:0042594 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement circadian regulation of heart rate ; GO:0003053 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | non-traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement eclosion rhythm ; GO:0008062 | non-traceable author statement" transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR001067 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001067 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001067 nucleus ; GO:0005634 | non-traceable author statement "cyc, CYC, Cyc, dCYC, dbmal, Cycle, Bmal1, dBMAL1, dBma1, CYCLE, BMAL1, MOP3, bMAL1, dBmal, dBMAL, dbmal1, Mop3, CG8727, bHLHe7, TGO_CYC" "IPR000014:PAS domain, IPR001067:Nuclear translocator, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR013767:PAS fold" CG8727 11-Aug-17 DroID_v2017_08 "Drer\ncoa3, Drer\ncoa2, Drer\arntl2, Drer\arntl1a, Drer\arntl1b, Drer\clockb, Drer\ncoa1" - "Cele\ref-1, Cele\aha-1" Xtro\arntl "Mmus\Clock, Mmus\Ncoa3, Mmus\Arntl2, Mmus\Arntl" "Hsap\PASD1, Hsap\ARNTL, Hsap\ARNTL2" adult stage head

"locomotor rhythm defective,recessive,circadian rhythm defective,sleep defective,behavior defective,visual behavior defective,mating rhythm defective,male limited,eclosion rhythm defective,male,viable" LN period neuron FBgn0017567 ND-23 NADH dehydrogenase (ubiquinone) 23 kDa subunit http://flybase.org/reports/FBgn0017567 FBgn0038370 protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR010226 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O00217" "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O00217" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O00217 mitochondrion ; GO:0005739 | inferred from direct assay "CG3944, ND23, ND 23, NUIM, ND-23" "IPR010226:NADH-quinone oxidoreductase, chain I, IPR017896:4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR017900:4Fe-4S ferredoxin, iron-sulphur binding, conserved site" CG3944 11-Aug-17 DroID_v2017_08 "Drer\ndufs8a, Drer\ndufs8b" - Cele\T20H4.5 Xtro\ndufs8 Mmus\Ndufs8 Hsap\NDUFS8 "viable,visible" trichogen cell FBgn0031734 CG11147 - http://flybase.org/reports/FBgn0031734 protein_coding_gene "ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871" transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR000412 neurogenesis ; GO:0022008 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000412 CG11147 "IPR000412:ABC-2 transporter, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG11147 11-Aug-17 DroID_v2017_08 "Drer\abca1b, Drer\abca12, Drer\abch1, Drer\abca5, Drer\abca2, Drer\abca3b, Drer\abca1a" - "Cele\Y6E2A.1, Cele\abt-6" "Xtro\abca9, Xtro\abca3, Xtro\abca4, Xtro\abcg2, Xtro\abca8, Xtro\abca10, Xtro\abca1, Xtro\abca2" "Mmus\Abca5, Mmus\Abca13, Mmus\Abca14, Mmus\Abca7, Mmus\Abca16, Mmus\Abca3, Mmus\Abca15, Mmus\Abca8b, Mmus\Abca8a, Mmus\Abca6, Mmus\Abca12, Mmus\Abca9, Mmus\Abca17, Mmus\Abca1, Mmus\Abca4, Mmus\Abca2" "Hsap\ABCA6, Hsap\ABCA10, Hsap\ABCA8, Hsap\ABCA12, Hsap\ABCA2, Hsap\ABCA13, Hsap\ABCA9, Hsap\ABCA7, Hsap\ABCA4, Hsap\ABCA5, Hsap\ABCA3, Hsap\ABCA1, Hsap\ABCG2" "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" ganglion mother cell FBgn0267878 CR46166 - http://flybase.org/reports/FBgn0267878 pseudogene_attribute - - - CR46166 - CR46166 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022001 l(2)k09318 lethal (2) k09318 http://flybase.org/reports/FBgn0022001 - gene - - - l(2)k09318 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013228 E(var)130 E(var)130 http://flybase.org/reports/FBgn0013228 - gene - - - E(var)130 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0015435 l(1)5ACa lethal (1) 5ACa http://flybase.org/reports/FBgn0015435 - gene - - - l(1)5ACa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001815 l(1)ne nonevaginated http://flybase.org/reports/FBgn0001815 - gene - - - l(1)ne - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "dorsal thoracic disc,ventral thoracic disc,genital disc,testis,pupal cuticle,imaginal disc" FBgn0024575 l(3)rK315 lethal (3) rK315 http://flybase.org/reports/FBgn0024575 - gene - - - l(3)rK315 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058455 2SrRNA:CR40455 2SrRNA:CR40455 http://flybase.org/reports/FBgn0058455 rRNA_gene - - - "CR40455, 2SrRNA:CR40455" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086698 frtz fritz http://flybase.org/reports/FBgn0086698 protein_coding_gene - imaginal disc-derived wing hair site selection ; GO:0035320 | inferred from mutant phenotype - "CG17657, anon-WO0118547.105, frtz, fritz" "IPR024511:WD repeat-containing and planar cell polarity effector protein Fritz, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG17657 11-Aug-17 DroID_v2017_08 Drer\wdpcp - - Xtro\wdpcp Mmus\Wdpcp Hsap\WDPCP FBgn0069250 attP:Dps1 pseudo attP recognition site Dps1 http://flybase.org/reports/FBgn0069250 region - - - attP:Dps1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010699 l(2)s4830 lethal (2) s4830 http://flybase.net/reports/FBgn0010699.html gene 11-Aug-17 DroID_v2017_08 "partially lethal - majority die,lethal,recessive" "crystal cell,mitotic cell cycle" FBgn0266074 CR44827 - http://flybase.org/reports/FBgn0266074 non_protein_coding_gene - - - CR44827 - CR44827 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267228 CR45668 - http://flybase.org/reports/FBgn0267228 non_protein_coding_gene - - - "CR45668, lincRNA.953" - CR45668 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037422 Osi13 Osiris 13 http://flybase.org/reports/FBgn0037422 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG15595, Osi13" IPR012464:Protein of unknown function DUF1676 CG15595 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034704 CG6758 - http://flybase.org/reports/FBgn0034704 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG6758, FBXO6" "IPR015915:Kelch-type beta propeller, IPR001810:F-box domain" CG6758 11-Aug-17 DroID_v2017_08 "Drer\klhdc3, Drer\klhdc4, Drer\klhdc10, Drer\zmp:0000001301, Drer\zgc:163014, Drer\hcfc1a, Drer\fbxo42, Drer\hcfc1b, Drer\krcp, Drer\rabepk, Drer\si:dkey-3d4.3" "Scer\KEL3, Scer\KEL1, Scer\KEL2" "Cele\F53E4.1, Cele\Y50D7A.1, Cele\hcf-1" "Xtro\rabepk, Xtro\klhdc1, Xtro\klhdc10, Xtro\fbxo42, Xtro\klhdc2, Xtro\klhdc9" "Mmus\Klhdc1, Mmus\Hcfc2, Mmus\Lztr1, Mmus\Klhdc4, Mmus\Fbxo42, Mmus\Klhdc10, Mmus\Klhdc2, Mmus\Klhdc9, Mmus\Hcfc1, Mmus\Rabepk, Mmus\Klhdc3" "Hsap\RABEPK, Hsap\KLHDC1, Hsap\KLHDC9, Hsap\KLHDC3, Hsap\FBXO42, Hsap\HCFC1, Hsap\KLHDC4, Hsap\KLHDC2, Hsap\LZTR1, Hsap\KLHDC10, Hsap\HCFC2" viable FBgn0265806 CR44595 - http://flybase.org/reports/FBgn0265806 non_protein_coding_gene - - - "lincRNA.122, CR44595" - CR44595 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001056 Fs(3)Kel Female sterile (3) Keled http://flybase.org/reports/FBgn0001056 - gene - - - "Fs(3)Keled, Fs(3)Sz15, Fs(3)Kel" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0033648 Ir48b Ionotropic receptor 48b http://flybase.org/reports/FBgn0033648 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir48b, DmelIR48b, CG13195, IR48b" - CG13195 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266960 CR45411 - http://flybase.org/reports/FBgn0266960 non_protein_coding_gene - - - CR45411 - CR45411 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021754 2R-L 2R-L http://flybase.org/reports/FBgn0021754 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 2R-L - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone" FBgn0002407 l(3)99Dh lethal (3) 99Dh http://flybase.org/reports/FBgn0002407 - gene - - - l(3)99Dh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085075 l(3)S024329 l(3)S024329 http://flybase.org/reports/FBgn0085075 gene - - - l(3)S024329 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005102 Gt-2 Giant on 2 http://flybase.org/reports/FBgn0005102 - gene - - - "Gt-2, Gt2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260373 GSd480 - http://flybase.org/reports/FBgn0260373 gene - - - GSd480 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002372 l(3)92Aa lethal (3) 92Aa http://flybase.org/reports/FBgn0002372 FBgn0002378 gene - - - "l(3)91Fd, C4, l(3)C4-6, l(3)C4-21, l(3)C4-20, l(3)C4-2, l(3)C4-1, l(3)BE72, l(3)BE71, l(3)BE70, l(3)92Ad, l(3)92Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083304 E(smoDN)1575 Enhancer of smoDN 1575 http://flybase.org/reports/FBgn0083304 gene - - - E(smoDN)1575 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032789 CG13083 - http://flybase.org/reports/FBgn0032789 protein_coding_gene - - chorion ; GO:0042600 | inferred from direct assay CG13083 - CG13083 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,visible" mesothoracic tergum DRSC28424 K 0.320902357 -0.151721468 -0.480618177 -0.310939835 1.604997907 4.361442544 FBgn0025348 anon-11a anon-11a http://flybase.org/reports/FBgn0025348 - gene - - - anon-11a - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010320 Cdi12 Cyclin-dependent kinase interactor 12 http://flybase.org/reports/FBgn0010320 - gene - - - "CDI12, cdi12, Cdi12" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065220 l(2)SH2232 lethal (2) SH2232 http://flybase.org/reports/FBgn0065220 gene - - - "l(2)SH2232, l(2)SH2 2232" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261703 gce germ cell-expressed bHLH-PAS http://flybase.org/reports/FBgn0261703 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ftz-f1 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with Met juvenile hormone binding ; GO:0005500 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with ftz-f1 juvenile hormone receptor activity ; GO:0004880 | inferred from mutant phenotype" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype juvenile hormone mediated signaling pathway ; GO:0035626 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with Met regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype negative regulation of programmed cell death ; GO:0043069 | inferred from genetic interaction with Met" transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR001067 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001067 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001067 nucleus ; GO:0005634 | inferred by curator from GO:0003700 "gce, CG42739, CG6211, Dmgce, CG15032, GCE, Gce/Met2, Gce" "IPR000014:PAS domain, IPR001067:Nuclear translocator, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG42739 11-Aug-17 DroID_v2017_08 "Drer\arntl1b, Drer\arntl1a" - "Cele\ref-1, Cele\aha-1" - "Mmus\Arntl, Mmus\Arntl2" "Hsap\ARNTL2, Hsap\PASD1, Hsap\ARNTL" FBgn0029042 l(2)E22 lethal (2) E22 http://flybase.org/reports/FBgn0029042 gene - - - "E22, l(2)E22" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,phototaxis defective" FBgn0263901 l(3)CMV45 - http://flybase.org/reports/FBgn0263901 gene - - - l(3)CMV45 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0051825 CG31825 - http://flybase.org/reports/FBgn0051825 protein_coding_gene - - - CG31825 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013334 Sap47 Synapse-associated protein 47kD http://flybase.org/reports/FBgn0013334 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available associative learning ; GO:0008306 | inferred from mutant phenotype regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from direct assay chemical synaptic transmission ; GO:0007268 | non-traceable author statement synapse ; GO:0045202 | inferred from direct assay "SAP-47, SAP47, sap47, dsap-47, CG8884, Sap47, SAP 47" IPR005607:BSD domain CG8884 11-Aug-17 DroID_v2017_08 Drer\syap1 - Cele\C16C2.4 Xtro\syap1 Mmus\Syap1 Hsap\SYAP1 "viable,fertile,learning defective" FBgn0262424 mir-10 mir-10 stem loop http://flybase.org/reports/FBgn0262424 miRNA_gene - - - "miR-10, mir-10, pri-mir-10, MIR-10, CR42977, CR32942, miR-10a, dme-mir-10, CR33565, mir-10*, mir-10S, miR-10*, dme-miR-10, dme-miR-10-5p" - CR42977 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal" "wing,wing vein L3,wing vein L5,wing vein,ectopic,embryonic/larval cuticle" FBgn0001010 fs(3)A1 female sterile (3) A1 http://flybase.org/reports/FBgn0001010 - gene - - - fs(3)A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "ovary,oocyte" FBgn0028481 CG4341 - http://flybase.org/reports/FBgn0028481 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GH12144, CG4341" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR013618:Domain of unknown function DUF1736, IPR019734:Tetratricopeptide repeat" CG4341 11-Aug-17 DroID_v2017_08 "Drer\tmtc2b, Drer\tmtc4, Drer\tmtc2a, Drer\tmtc1" - Cele\F32D1.3 "Xtro\tmtc4, Xtro\tmtc2" "Mmus\Tmtc4, Mmus\Tmtc2" "Hsap\TMTC2, Hsap\TMTC4" "viable,fertile" FBgn0037171 CG14459 - http://flybase.org/reports/FBgn0037171 protein_coding_gene - - - CG14459 - CG14459 11-Aug-17 DroID_v2017_08 - - - - - - lethal DRSC23039 K -0.422110396 -2.023866895 FBgn0263929 jvl javelin-like http://flybase.org/reports/FBgn0263929 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype oocyte nucleus localization involved in oocyte dorsal/ventral axis specification ; GO:0051663 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype RNA localization ; GO:0006403 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype oocyte growth in germarium-derived egg chamber ; GO:0030715 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype microtubule cytoskeleton ; GO:0015630 | inferred from direct assay "jvl, CG3563, CG43162, anon-WO0153538.5, anon-WO0153538.4, CG33330, Jvl" - CG43162 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262409 mir-304 mir-304 stem loop http://flybase.org/reports/FBgn0262409 miRNA_gene - positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype - "mir-304, dme-mir-304, miR-304, 304, CR42953, miR304, CR33607, MiR-304, dme-miR-304" - CR42953 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037428 Osi18 Osiris 18 http://flybase.org/reports/FBgn0037428 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi18, CG1169" IPR012464:Protein of unknown function DUF1676 CG1169 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065295 l(2)SH2001 lethal (2) SH2001 http://flybase.org/reports/FBgn0065295 gene - - - "l(2)SH2001, l(2)SH2 2001" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032304 CG17134 - http://flybase.org/reports/FBgn0032304 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 lysosome ; GO:0005764 | inferred from electronic annotation with InterPro:IPR033144 CG17134 "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR033144:Cathepsin D, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG17134 11-Aug-17 DroID_v2017_08 "Drer\ren, Drer\zgc:103530, Drer\ctsd, Drer\zgc:63831, Drer\nots" "Scer\YPS6, Scer\YPS3, Scer\BAR1, Scer\YPS1, Scer\PEP4, Scer\YGL258W-A, Scer\YPS5, Scer\YPS7, Scer\MKC7" "Cele\asp-3, Cele\asp-19, Cele\asp-4, Cele\asp-10, Cele\asp-15, Cele\asp-16, Cele\asp-2, Cele\asp-13, Cele\asp-6, Cele\asp-1, Cele\asp-7, Cele\asp-12, Cele\asp-17, Cele\asp-5, Cele\asp-8, Cele\asp-9, Cele\asp-18" "Xtro\bace2, Xtro\ctse, Xtro\pgc, Xtro\ren, Xtro\napsa, Xtro\LOC496913, Xtro\pga4, Xtro\bace1, Xtro\ctsd" "Mmus\Ctsd, Mmus\Bace1, Mmus\Ren1, Mmus\Napsa, Mmus\Pgc, Mmus\Pga5, Mmus\Cym, Mmus\Ctse, Mmus\Bace2" "Hsap\PGA4, Hsap\REN, Hsap\BACE1, Hsap\NAPSA, Hsap\PGA5, Hsap\PGA3, Hsap\CTSE, Hsap\PGC, Hsap\CTSD, Hsap\BACE2" viable FBgn0027981 l(3)S135710 lethal (3) S135710 http://flybase.org/reports/FBgn0027981 gene - - - "1357/10, l(3)S135710" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033183 CG1620 - http://flybase.org/reports/FBgn0033183 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 - - "146745_at, CG1620" "IPR000949:ELM2 domain, IPR001005:SANT/Myb domain, IPR017884:SANT domain, IPR009057:Homeobox domain-like" CG1620 11-Aug-17 DroID_v2017_08 "Drer\mier1b, Drer\mier2, Drer\mier3b, Drer\mier3a, Drer\mier1a" - "Cele\T07F8.4, Cele\F10E7.11" "Xtro\elmsan1, Xtro\mier2, Xtro\mier3, Xtro\mier1" "Mmus\Mier2, Mmus\Mier1, Mmus\Mier3" "Hsap\MIER1, Hsap\MIER2, Hsap\MIER3" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0005730 l(1)TK206 lethal (1) TK206 http://flybase.org/reports/FBgn0005730 - gene - - - "l206, l(1)TK206" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002671 mat(2)ea-H maternal effect early arrest H http://flybase.org/reports/FBgn0002671 - gene - - - "RU28, mat(2)earlyRU28, mat(2)ea-H" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0260626 d00992 - http://flybase.org/reports/FBgn0260626 gene - - - d00992 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0038494 beat-IIb beat-IIb http://flybase.org/reports/FBgn0038494 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic - "beat IIb, CT13620, CG14337, CG4135, beat-IIb, Beat-IIb" "IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain" CG4135 11-Aug-17 DroID_v2017_08 Drer\zgc:172106 - - Xtro\f11r - Hsap\CADM2 viable DRSC13219 I -1.753198168 0.211633154 -0.238612904 -0.111140162 0.612141904 0.513563986 FBgn0083066 quil quilapan http://flybase.org/reports/FBgn0083066 gene - - - quil - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052822 CG32822 - http://flybase.org/reports/FBgn0052822 protein_coding_gene - - - CG32822 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0035036 CG4707 - http://flybase.org/reports/FBgn0035036 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG4707, Cg4707" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG4707 11-Aug-17 DroID_v2017_08 "Drer\zgc:153116, Drer\prdm5, Drer\prdm10" - "Cele\hinf-1, Cele\ZK686.5, Cele\row-1" Xtro\znf142 "Mmus\Prdm10, Mmus\Zfp341" "Hsap\ZBTB48, Hsap\PRDM10, Hsap\ZNF341, Hsap\ZNF83, Hsap\PRDM5" viable FBgn0038718 CG17752 - http://flybase.org/reports/FBgn0038718 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG17752 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG17752 11-Aug-17 DroID_v2017_08 "Drer\slc22a21, Drer\slc22a5" "Scer\HXT2, Scer\HXT5, Scer\PHO84, Scer\HXT9, Scer\GIT1" "Cele\Y66D12A.13, Cele\B0252.3, Cele\Y51A2D.18, Cele\C06H5.6, Cele\oct-1, Cele\Y57G11C.23, Cele\C46C2.2, Cele\C53B4.1, Cele\T22F7.1, Cele\ZK892.3, Cele\B0361.11" - "Mmus\Slc22a4, Mmus\Slc22a5, Mmus\Slc22a21, Mmus\Slc22a28" "Hsap\SLC22A5, Hsap\SLC22A25, Hsap\SLC22A4" viable FBgn0067646 sdv sedov http://flybase.org/reports/FBgn0067646 gene - pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype - sdv - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "nurse cell,germline clone,follicle cell,supernumerary" FBgn0058182 CR40182 - http://flybase.org/reports/FBgn0058182 pseudogene_attribute - - - "CR40182, CG40182" - CR40182 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069448 E(br)24 E(br)24 http://flybase.org/reports/FBgn0069448 gene molecular_function ; GO:0003674 | no biological data available dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available E(br)24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,semidominant" "embryonic/first instar larval cuticle,anterior,leg" FBgn0034558 Cib2 Calcium and integrin binding family member 2 http://flybase.org/reports/FBgn0034558 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium-dependent protein serine/threonine phosphatase activity ; GO:0004723 | contributes_to inferred from sequence or structural similarity with SGD:S000001673 calcium ion homeostasis ; GO:0055074 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype calcineurin complex ; GO:0005955 | inferred from sequence or structural similarity with SGD:S000001673 "Cib2, CG9236, cib2" "IPR002048:EF-hand domain, IPR018247:EF-Hand 1, calcium-binding site, IPR011992:EF-hand domain pair" CG9236 11-Aug-17 DroID_v2017_08 "Drer\cib1, Drer\cib2, Drer\LOC100536377, Drer\cib3" Scer\CNB1 Cele\calm-1 "Xtro\cib3, Xtro\cib1, Xtro\cib2" "Mmus\Cib1, Mmus\Cib2, Mmus\Cib4, Mmus\Cib3" "Hsap\CIB4, Hsap\CIB3, Hsap\CIB2" "visible,partially lethal - majority die,some die during pupal stage,neuroanatomy defective,conditional,neurophysiology defective" "trichogen cell,eye photoreceptor cell,conditional" FBgn0003480 spn-B spindle B http://flybase.org/reports/FBgn0003480 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR020588 four-way junction DNA binding ; GO:0000400 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from sequence or structural similarity with HGNC:12830 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 endodeoxyribonuclease activity ; GO:0004520 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001415033 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 DNA-dependent ATPase activity ; GO:0008094 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 regulation of translation ; GO:0006417 | traceable author statement chromosome condensation ; GO:0030261 | traceable author statement reciprocal meiotic recombination ; GO:0007131 | traceable author statement mitotic recombination ; GO:0006312 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 oocyte fate determination ; GO:0030716 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype strand invasion ; GO:0042148 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 oogenesis ; GO:0048477 | inferred from genetic interaction with fs(1)K10 inferred from genetic interaction with fs(1)K10 DNA recombination ; GO:0006310 | inferred from sequence or structural similarity with HGNC:12830 polarity specification of dorsal/ventral axis ; GO:0009951 | inferred from mutant phenotype polarity specification of anterior/posterior axis ; GO:0009949 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from sequence or structural similarity with HGNC:12830 intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with mus301 DNA repair ; GO:0006281 | non-traceable author statement meiotic DNA recombinase assembly ; GO:0000707 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 intracellular mRNA localization ; GO:0008298 | traceable author statement response to ionizing radiation ; GO:0010212 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 double-strand break repair ; GO:0006302 | traceable author statement Rad51B-Rad51C-Rad51D-XRCC2 complex ; GO:0033063 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 replication fork ; GO:0005657 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 "spnB, SpnB, CG3325, spn-B, rad51-like, Rad51, XRCC3, Spn-B, Rad51-like" "IPR013632:DNA recombination and repair protein Rad51-like, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033925:Rad51/DMC1/RadA, IPR020588:DNA recombination and repair protein RecA-like, ATP-binding domain" CG3325 11-Aug-17 DroID_v2017_08 "Drer\rad51c, Drer\xrcc3" Scer\RAD57 - Xtro\xrcc3 "Mmus\Rad51c, Mmus\Xrcc3, Mmus\Rad51b" "Hsap\RAD51B, Hsap\XRCC3" "wild-type,viable,radiation sensitive,female sterile,recessive,planar polarity defective" "dorsal appendage,egg,karyosome,synaptonemal complex,germline cyst,dorsal,oocyte,nurse cell,chorion | maternal effect,maternal effect,nuclear membrane & oocyte nucleus,oocyte nucleus,oocyte nucleus & meiotic cell cycle,presumptive oocyte" FBgn0023478 TfIIZ Transcription factor IIZ http://flybase.org/reports/FBgn0023478 - gene - - - "TFIIZ, TfIIZ" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001778 l(1)M60 lethal (1) M60 http://flybase.org/reports/FBgn0001778 - gene - - - l(1)M60 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259375 C293 - http://flybase.org/reports/FBgn0259375 gene - - - C293 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing,wing vein,chaeta" FBgn0037534 CG2781 - http://flybase.org/reports/FBgn0037534 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available CG2781 IPR002076:ELO family CG2781 11-Aug-17 DroID_v2017_08 "Drer\elovl7a, Drer\elovl1b, Drer\elovl8b, Drer\elovl5, Drer\elovl1a, Drer\elovl7b, Drer\elovl2, Drer\zgc:101858, Drer\dhrs7, Drer\hsd17b8, Drer\elovl4b, Drer\elovl8a, Drer\elovl4a" "Scer\ELO3, Scer\ELO2, Scer\ELO1" "Cele\elo-6, Cele\elo-7, Cele\dhs-14, Cele\dhs-11, Cele\F26D2.15, Cele\F25D1.5, Cele\dhs-25, Cele\Y47G6A.21, Cele\F28H7.2, Cele\Y47G6A.22, Cele\ZK829.1, Cele\elo-1, Cele\C06E4.3" "Xtro\elovl1, Xtro\elovl7, Xtro\cbr4, Xtro\MGC79752, Xtro\hsd17b8, Xtro\elovl5, Xtro\dhrs7, Xtro\elovl2" "Mmus\Cbr4, Mmus\Elovl1, Mmus\Elovl2, Mmus\Dhrs7, Mmus\Elovl4, Mmus\Elovl7, Mmus\Elovl5, Mmus\H2-Ke6" "Hsap\HSD17B8, Hsap\ELOVL4, Hsap\ELOVL5, Hsap\DHRS7, Hsap\CBR4, Hsap\ELOVL1, Hsap\ELOVL7, Hsap\ELOVL2" lethal FBgn0036974 eRF1 eukaryotic translation release factor 1 http://flybase.org/reports/FBgn0036974 protein_coding_gene "translation release factor activity, codon specific ; GO:0016149 | inferred from electronic annotation with InterPro:IPR004403 translation termination factor activity ; GO:0008079 | inferred from sequence or structural similarity" translational termination ; GO:0006415 | inferred from sequence or structural similarity smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo translational termination ; GO:0006415 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004403 cytosol ; GO:0005829 | inferred from sequence or structural similarity "group J, Group J, CG5605, l(3)77ABb, Dm0184, l(3)neo28, l(3)00103, l(3)05637, eRF1" "IPR004403:Peptide chain release factor eRF1/aRF1, IPR005140:eRF1 domain 1/Pelota-like, IPR005141:eRF1 domain 2, IPR005142:eRF1 domain 3, IPR024049:Peptide Chain Release Factor eRF1/aRF1, N-terminal, IPR029064:50S ribosomal protein L30e-like" CG5605 11-Aug-17 DroID_v2017_08 "Drer\etf1a, Drer\etf1b" Scer\SUP45 Cele\erfa-1 Xtro\etf1 Mmus\Etf1 Hsap\ETF1 "lethal,recessive,partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage,cell lethalcell lethal,somatic clone" "dorsocentral bristle,scutellar bristle,trichogen cell,tormogen cell" DRSC11779 E -0.129932628 0.027598073 1.384228708 -2.087196174 0.528971465 1.035170051 FBgn0004558 Su(var)307 Suppressor of variegation 307 http://flybase.org/reports/FBgn0004558 - gene - - - "Su(var)307, 307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0003208 gua1 guanosine 1 http://flybase.org/reports/FBgn0003208 - gene - - - "gua-1, l(1)S27, l(1)RC1, l(1)N23, l(1)K27, l(1)J5, l(1)H6, l(1)H25, l(1)F19, l(1)F1, l(1)EA140, l(1)E6, l(1)DC819, l(1)D12, gua1-1[ts], gua1-1, gua1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "auxotroph,heat sensitive" FBgn0065730 l(2)SH0555 lethal (2) SH0555 http://flybase.org/reports/FBgn0065730 gene - - - "l(2)SH0555, l(2)SH2 0555" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263879 l(3)PL13 - http://flybase.org/reports/FBgn0263879 gene - - - l(3)PL13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of P-stage,recessive,some die during P-stage" "embryonic/larval neuroblast,embryonic/larval brain,embryonic/larval optic lobe" FBgn0050225 tRNA:Val-AAC-2-1 transfer RNA:Valine-AAC 2-1 http://flybase.org/reports/FBgn0050225 tRNA_gene GUU codon-amino acid adaptor activity ; GO:0033449 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033449 cytosol ; GO:0005829 | inferred by curator from GO:0033449 "CR30225, AE002787.trna51-ValAAC, valine tRNA, tRNA[Val][[4]], tRNA:val4:56D, tRNA:V4:56D, tRNA:V:AAC:AE002787-a, tRNA[Val-AAC], chr2R.trna34-ValAAC, tRNA:Val-AAC-2-1, tRNA:CR30225, tRNA-Val-AAC-2-1, GUU" - CR30225 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035068 CG12849 - http://flybase.org/reports/FBgn0035068 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12849 IPR010512:Protein of unknown function DUF1091 CG12849 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037536 CG2698 - http://flybase.org/reports/FBgn0037536 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG2698 IPR002549:Transmembrane protein TqsA-like CG2698 11-Aug-17 DroID_v2017_08 "Drer\LOC100536614, Drer\tmem245" - Cele\M01F1.4 Xtro\tmem245 Mmus\Tmem245 Hsap\TMEM245 "viable,fertile" FBgn0260499 qvr quiver http://flybase.org/reports/FBgn0260499 protein_coding_gene GPI anchor binding ; GO:0034235 | inferred from direct assay "positive regulation of voltage-gated potassium channel activity ; GO:1903818 | inferred from electronic annotation with InterPro:IPR031424 sleep ; GO:0030431 | inferred from genetic interaction with nAChRα4 positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype negative regulation of acetylcholine-gated cation channel activity ; GO:1903049 | inferred from genetic interaction with nAChRα3 inferred from genetic interaction with nAChRβ3 regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype regulation of synaptic transmission, cholinergic ; GO:0032222 | inferred from mutant phenotype negative regulation of membrane potential ; GO:0045837 | inferred from genetic interaction with nAChRα4" plasma membrane ; GO:0005886 | inferred from direct assay external side of plasma membrane ; GO:0009897 | inferred from direct assay voltage-gated potassium channel complex ; GO:0008076 | colocalizes_with inferred from direct assay "CG33472, qvr, sss, CG30032, BcDNA:GH06755, anon-WO02059370.1, mdcds_22455" IPR031424:Protein quiver CG33472 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033086 CG9410 - http://flybase.org/reports/FBgn0033086 protein_coding_gene ubiquinone binding ; GO:0048039 | inferred from biological aspect of ancestor with PANTHER:PTN002293076 cellular respiration ; GO:0045333 | inferred from biological aspect of ancestor with PANTHER:PTN002293076 ubiquinone biosynthetic process ; GO:0006744 | inferred from biological aspect of ancestor with PANTHER:PTN002293076 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q08058 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN002293076 CG9410 "IPR005031:Coenzyme Q-binding protein COQ10, START domain, IPR023393:START-like domain" CG9410 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-190g6.2, Drer\si:ch73-141c7.1, Drer\coq10b" Scer\COQ10 "Cele\R144.13, Cele\R144.3" "Xtro\coq10a, Xtro\coq10b" "Mmus\Coq10b, Mmus\Coq10a" "Hsap\COQ10A, Hsap\COQ10B" viable FBgn0060310 l(3)S147915d lethal (3) S147915d http://flybase.org/reports/FBgn0060310 gene - - - "1479/15, l(3)S147915d" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263897 l(3)A11 - http://flybase.org/reports/FBgn0263897 gene - - - l(3)A11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0263483 snoRNA:lola-d - http://flybase.org/reports/FBgn0263483 snoRNA_gene - - - "snoRNA:lola-d, chr2R:6048993..6049090" - CR43598 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261600 M(3)98B Minute (3) 98B http://flybase.org/reports/FBgn0261600 gene - - - M(3)98B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005440 l(1)v132 lethal (1) v132 http://flybase.org/reports/FBgn0005440 - gene - - - "l(1)132, l(1)v132" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039804 CG15544 - http://flybase.org/reports/FBgn0039804 protein_coding_gene - - - CG15544 - CG15544 11-Aug-17 DroID_v2017_08 - - "Cele\T11F9.13, Cele\F41C6.3" - - - viable FBgn0065960 l(2)SH0037 lethal (2) SH0037 http://flybase.org/reports/FBgn0065960 gene - - - l(2)SH0037 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002027 l(2)37Bi lethal (2) 37Bi http://flybase.org/reports/FBgn0002027 - gene - - - "Bi, l(2)E131, l(2)37Bi" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031247 CG11562 - http://flybase.org/reports/FBgn0031247 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from biological aspect of ancestor with PANTHER:PTN001999899 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:40045 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001999899 "BcDNA:RE44650, CG11562" "IPR031568:Protein Pet117, mitochondrial" CG11562 11-Aug-17 DroID_v2017_08 "Drer\pet117, Drer\si" Scer\PET117 - - Mmus\Pet117 Hsap\PET117 lethal FBgn0001430 l(1)6Fc lethal (1) 6Fc http://flybase.org/reports/FBgn0001430 - gene - - - l(1)6Fc - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0065152 l(3)SH065 lethal (3) SH065 http://flybase.org/reports/FBgn0065152 gene - - - "l(3)SH065, l(2)SH3 065" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051469 CG31469 - http://flybase.org/reports/FBgn0051469 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR017867 protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from sequence model protein arginine phosphatase activity ; GO:0098627 | inferred from direct assay peptidyl-N-phospho-arginine dephosphorylation ; GO:0098628 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:122 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:122 "CG9599, CG31469" "IPR023485:Phosphotyrosine protein phosphatase I superfamily, IPR017867:Protein-tyrosine phosphatase, low molecular weight" CG31469 11-Aug-17 DroID_v2017_08 Drer\acp1 Scer\LTP1 Cele\Y94H6A.7 Xtro\acp1 Mmus\Acp1 Hsap\ACP1 viable FBgn0035844 CG13676 - http://flybase.org/reports/FBgn0035844 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG13676 IPR002557:Chitin binding domain CG13676 11-Aug-17 DroID_v2017_08 Drer\nucks1a - Cele\Y56A3A.6 - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0022104 l(2)k07110 lethal (2) k07110 http://flybase.org/reports/FBgn0022104 - gene - - - l(2)k07110 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262167 ana1 anastral spindle 1 http://flybase.org/reports/FBgn0262167 protein_coding_gene - cilium assembly ; GO:0060271 | inferred from mutant phenotype flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype ciliary basal body organization ; GO:0032053 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype centriole assembly ; GO:0098534 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay ciliary basal body ; GO:0036064 | inferred from direct assay "ana1, mecB, Ana1, CG6631, Ana-1, Ana 1, ANA1" - CG6631 11-Aug-17 DroID_v2017_08 - - - - - - "uncoordinated,temperature conditional" "centrosome,mechanosensory neuron,cilium,microtubule basal body,spermatid axoneme,spermatozoon" FBgn0015502 l(3)65CEf lethal (3) 65CEf http://flybase.org/reports/FBgn0015502 - gene - - - "XV, l(3)65CEf" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044098 E(rst)C7 E(rst)C7 http://flybase.org/reports/FBgn0044098 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C7, E(rst)C7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065332 l(2)SH1871 lethal (2) SH1871 http://flybase.org/reports/FBgn0065332 gene - - - "l(2)SH1871, l(2)SH2 1871" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061118 l(3)S005302b lethal (3) S005302b http://flybase.org/reports/FBgn0061118 gene - - - "0053/02, l(3)S005302b" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023506 Es2 Es2 http://flybase.org/reports/FBgn0023506 - protein_coding_gene - "nervous system development ; GO:0007399 | inferred from sequence or structural similarity with UniProtKB:O70279 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:107854 "CG1474, Es2, es, ES2" IPR019148:Nuclear protein DGCR14 CG1474 11-Aug-17 DroID_v2017_08 Drer\dgcr14 - Cele\ess-2 Xtro\dgcr14 Mmus\Dgcr14 Hsap\DGCR14 "partially lethal - majority die,some die during pupal stage" FBgn0052442 Arv1 ACAT-related protein required for viability 1 http://flybase.org/reports/FBgn0052442 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of cell division ; GO:0051781 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "BcDNA:RH17480, BcDNA:RE62711, CG32442, Arv1" IPR007290:Arv1 protein CG32442 11-Aug-17 DroID_v2017_08 Drer\arv1 Scer\ARV1 Cele\R05H5.5 Xtro\arv1 Mmus\Arv1 Hsap\ARV1 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037152 CG15374 - http://flybase.org/reports/FBgn0037152 protein_coding_gene - - - CG15374 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031717 Oscillin Oscillin http://flybase.org/reports/FBgn0031717 protein_coding_gene glucosamine-6-phosphate deaminase activity ; GO:0004342 | inferred from sequence or structural similarity with UniProtKB:P46926 glucosamine-6-phosphate deaminase activity ; GO:0004342 | inferred from sequence or structural similarity with UniProtKB:P0A759 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006148 glucosamine catabolic process ; GO:0006043 | inferred from sequence or structural similarity with UniProtKB:P46926 N-acetylglucosamine metabolic process ; GO:0006044 | inferred from sequence or structural similarity with UniProtKB:P0A759 generation of precursor metabolites and energy ; GO:0006091 | inferred from sequence or structural similarity with UniProtKB:P46926 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:O88958 "CG6957, Oscillin" "IPR018321:Glucosamine-6-phosphate isomerase, conserved site, IPR004547:Glucosamine-6-phosphate isomerase, IPR006148:Glucosamine/galactosamine-6-phosphate isomerase" CG6957 11-Aug-17 DroID_v2017_08 "Drer\mppe1, Drer\gnpda1, Drer\gnpda2" - "Cele\T03F6.3, Cele\B0511.13" "Xtro\gnpda2, Xtro\mppe1, Xtro\gnpda1" "Mmus\Gnpda2, Mmus\Gnpda1, Mmus\Mppe1" "Hsap\GNPDA1, Hsap\GNPDA2, Hsap\MPPE1" FBgn0069354 Porin2 Porin2 http://flybase.org/reports/FBgn0069354 protein_coding_gene porin activity ; GO:0015288 | inferred from direct assay voltage-gated anion channel activity ; GO:0008308 | inferred from direct assay cation channel activity ; GO:0005261 | inferred from direct assay voltage-gated anion channel activity ; GO:0008308 | inferred from sequence or structural similarity with UniProtKB:P21796 anion transmembrane transport ; GO:0098656 | inferred from electronic annotation with InterPro:IPR001925 ion transport ; GO:0006811 | inferred from direct assay mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:P21796 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:P21796 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P21796 "CG17137, LP07660.3prime, DmPorin2, BEST:LP07660, Porin2, Porin 2, porin 2" "IPR001925:Porin, eukaryotic type, IPR027246:Eukaryotic porin/Tom40" CG17137 11-Aug-17 DroID_v2017_08 "Drer\vdac2, Drer\LOC101886830, Drer\vdac1, Drer\vdac3, Drer\zgc:56235" "Scer\POR2, Scer\POR1" Cele\vdac-1 "Xtro\vdac2, Xtro\vdac3, Xtro\vdac1" "Mmus\Vdac1, Mmus\Vdac3, Mmus\Vdac2" "Hsap\VDAC2, Hsap\VDAC3, Hsap\VDAC1" viable FBgn0264506 CR43905 - http://flybase.org/reports/FBgn0264506 non_protein_coding_gene - - - CR43905 - CR43905 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034709 Swim Secreted Wg-interacting molecule http://flybase.org/reports/FBgn0034709 protein_coding_gene "cysteine-type peptidase activity ; GO:0008234 | inferred from electronic annotation with InterPro:IPR000668, InterPro:IPR013128 polysaccharide binding ; GO:0030247 | inferred from electronic annotation with InterPro:IPR001212 scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001212 Wnt-protein binding ; GO:0017147 | inferred from direct assay" immune response ; GO:0006955 | inferred from electronic annotation with InterPro:IPR001212 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000668 cell adhesion ; GO:0007155 | inferred from biological aspect of ancestor with PANTHER:PTN000274687 sleep ; GO:0030431 | inferred from expression pattern positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from direct assay positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region ; GO:0035593 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay chorion ; GO:0042600 | inferred from direct assay "CG3074, dmw, Swim, swim" "IPR025661:Cysteine peptidase, asparagine active site, IPR025660:Cysteine peptidase, histidine active site, IPR000668:Peptidase C1A, papain C-terminal, IPR001212:Somatomedin B domain, IPR013128:Peptidase C1A" CG3074 11-Aug-17 DroID_v2017_08 Drer\tinagl1 - "Cele\F26E4.3, Cele\cpr-8" Xtro\tinagl1 "Mmus\Tinagl1, Mmus\Tinag" "Hsap\TINAG, Hsap\TINAGL1" "partially lethal - majority die,visible,viable,fertile" wing margin FBgn0064183 frag fragmented mitochondria http://flybase.org/reports/FBgn0064183 gene - - - frag - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031371 CG15363 - http://flybase.org/reports/FBgn0031371 protein_coding_gene - - - CG15363 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035877 CG7083 - http://flybase.org/reports/FBgn0035877 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7083 IPR005373:Uncharacterised protein family UPF0183 CG7083 11-Aug-17 DroID_v2017_08 Drer\si:dkey-102f14.5 - Cele\T01G9.2 Xtro\c16orf70 Mmus\D230025D16Rik Hsap\C16orf70 viable FBgn0052718 CG32718 - http://flybase.org/reports/FBgn0052718 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32718 - CG32718 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267529 CR45869 - http://flybase.org/reports/FBgn0267529 non_protein_coding_gene - - - CR45869 - CR45869 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265827 CR44616 - http://flybase.org/reports/FBgn0265827 non_protein_coding_gene - - - "lincRNA.84, CR44616" - CR44616 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261054 Sfp24Bc Seminal fluid protein 24Bc http://flybase.org/reports/FBgn0261054 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp24Bc, SFP24BC" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG42602 11-Aug-17 DroID_v2017_08 "Drer\tfpi2, Drer\ambp" - - - "Mmus\Tfpi, Mmus\Spint4, Mmus\Ambp" "Hsap\SPINT4, Hsap\TFPI, Hsap\AMBP" FBgn0033209 CG12107 - http://flybase.org/reports/FBgn0033209 protein_coding_gene - - - CG12107 "IPR010742:Rab5-interacting protein, IPR029008:Rab5-interacting protein family" CG12107 11-Aug-17 DroID_v2017_08 Drer\c23h20orf24 - Cele\F44E7.9 Xtro\c20orf24 Mmus\1110008F13Rik "Hsap\TGIF2-C20orf24, Hsap\C20orf24" viable FBgn0028255 l(3)79Ba lethal (3) 79Ba http://flybase.org/reports/FBgn0028255 gene - - - l(3)79Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263032 CG43327 - http://flybase.org/reports/FBgn0263032 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG30459, CG43327" IPR026769:MICOS complex subunit Mic13 CG43327 11-Aug-17 DroID_v2017_08 Drer\si:dkey-78l4.14 - Cele\W04C9.2 - Mmus\2410015M20Rik Hsap\C19orf70 FBgn0039633 CG11873 - http://flybase.org/reports/FBgn0039633 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.162, CG11873" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR015671:GLTSCR protein, conserved region" CG11873 11-Aug-17 DroID_v2017_08 "Drer\gltscr1, Drer\ncoa6" - - Xtro\gltscr1 Mmus\Gltscr1 "Hsap\GLTSCR1, Hsap\GLTSCR1L" lethal DRSC14417 E 0.964884036 -0.048324331 2.416082893 0.264860267 0.852290489 1.292673771 FBgn0030739 SWIP Strumpellin and WASH-interacting protein http://flybase.org/reports/FBgn0030739 protein_coding_gene - endosomal transport ; GO:0016197 | inferred from biological aspect of ancestor with PANTHER:PTN000776639 endosome organization ; GO:0007032 | inferred from biological aspect of ancestor with PANTHER:PTN000776639 WASH complex ; GO:0071203 | inferred from direct assay WASH complex ; GO:0071203 | inferred from sequence or structural similarity with UniProtKB:Q2M389 WASH complex ; GO:0071203 | inferred from biological aspect of ancestor with PANTHER:PTN000776639 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000776639 "SWIP, p116, KIAA1033, CG13957, swip" "IPR027307:WASH complex subunit 7, IPR028283:WASH complex subunit 7, C-terminal, IPR028282:WASH complex subunit 7, central domain, IPR028191:WASH complex subunit 7, N-terminal" CG13957 11-Aug-17 DroID_v2017_08 Drer\si:dkey-23p11.2 - Cele\Y53F4B.21 Xtro\kiaa1033 Mmus\A230046K03Rik Hsap\WASHC4 viable FBgn0050039 CG30039 - http://flybase.org/reports/FBgn0050039 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "NEST:bs25c07, NEST:bs15e10, BcDNA:AT09538, CG30039" - CG30039 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262384 mir-1014 mir-1014 stem loop http://flybase.org/reports/FBgn0262384 miRNA_gene - - - "dme-mir-1014, mir-1014, CR42909, miR-1014" - CR42909 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016717 Reg-21 Rhythmically expressed gene 21 http://flybase.org/reports/FBgn0016717 - gene - - - "Dreg-21, Reg-21" - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult head

FBgn0259700 CG42354 - http://flybase.org/reports/FBgn0259700 protein_coding_gene - - - "CG42354, CG9216" - CG42354 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266256 CR44951 - http://flybase.org/reports/FBgn0266256 non_protein_coding_gene - - - "CR44951, lincRNA.860" - CR44951 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002228 l(3)68Bg lethal (3) 68Bg http://flybase.org/reports/FBgn0002228 - gene - - - "l(3)C11, l(3)L, l(3)68Bg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal" FBgn0037493 CR10032 - http://flybase.org/reports/FBgn0037493 pseudogene_attribute - - - "CG10032, CR10032" "IPR000436:Sushi/SCR/CCP domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CR10032 11-Aug-17 DroID_v2017_08 - - "Cele\rme-2, Cele\egg-2, Cele\T13C2.6" - "Mmus\LOC102637808, Mmus\Ldlrad1" Hsap\LDLRAD1 FBgn0034053 Cyp4aa1 Cyp4aa1 http://flybase.org/reports/FBgn0034053 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972" - "4aa1, CG8302, Cyp4aa1, Cyp4AA1" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV, IPR017972:Cytochrome P450, conserved site" CG8302 11-Aug-17 DroID_v2017_08 "Drer\cyp46a1.4, Drer\cyp4t8, Drer\cyp26c1, Drer\LOC100329425, Drer\cyp19a1b, Drer\cyp19a1a, Drer\cyp26a1, Drer\cyp46a1.3, Drer\cyp26b1, Drer\cyp20a1, Drer\cyp46a1.2, Drer\cyp46a1.1, Drer\zgc:123299, Drer\cyp4f3, Drer\cyp4v7, Drer\cyp4v8" "Scer\ERG11, Scer\DIT2, Scer\ERG5" "Cele\cyp-32B1, Cele\cyp-29A3, Cele\cyp-29A2, Cele\cyp-29A4, Cele\cyp-37B1, Cele\cyp-32A1, Cele\cyp-31A3, Cele\cyp-42A1, Cele\cyp-37A1, Cele\cyp-31A2" "Xtro\cyp26c1, Xtro\cyp4f22, Xtro\cyp4b1, Xtro\LOC100487918, Xtro\LOC100488227, Xtro\mgc108213, Xtro\cyp4v2, Xtro\cyp4f2, Xtro\cyp19a1, Xtro\cyp26b1, Xtro\cyp20a1, Xtro\cyp4b1.2, Xtro\cyp26a1" "Mmus\Cyp4f14, Mmus\Cyp4a30b, Mmus\Cyp4a31, Mmus\Cyp4f15, Mmus\Cyp26c1, Mmus\Cyp4a12b, Mmus\Cyp4f37, Mmus\Cyp51, Mmus\Cyp26a1, Mmus\Cyp4f13, Mmus\Cyp19a1, Mmus\Cyp4f16, Mmus\Cyp4b1, Mmus\Cyp26b1, Mmus\Cyp4f17, Mmus\Cyp4x1, Mmus\Cyp4a29, Mmus\Cyp20a1, Mmus\Cyp4f40, Mmus\Cyp4v3, Mmus\Cyp46a1, Mmus\Cyp4a12a, Mmus\Cyp4f39, Mmus\Cyp4a14, Mmus\Cyp4a32, Mmus\Cyp4a10, Mmus\Cyp4f18" "Hsap\CYP4F12, Hsap\CYP4X1, Hsap\CYP20A1, Hsap\CYP4F22, Hsap\CYP4A11, Hsap\CYP4F3, Hsap\CYP4V2, Hsap\CYP4F8, Hsap\CYP26C1, Hsap\CYP26A1, Hsap\CYP4A22, Hsap\CYP51A1, Hsap\CYP4B1, Hsap\CYP19A1, Hsap\CYP4F2, Hsap\CYP26B1, Hsap\CYP4F11, Hsap\CYP4Z1, Hsap\CYP46A1" FBgn0052739 CR32739 - http://flybase.org/reports/FBgn0052739 non_protein_coding_gene - - - CR32739 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003709 tipD temperature-induced paralytic D http://flybase.org/reports/FBgn0003709 - gene - - - tipD - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,heat sensitive" FBgn0004892 sob sister of odd and bowl http://flybase.org/reports/FBgn0004892 - protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with odd" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with odd negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with UniProtKB:P23803 blastoderm segmentation ; GO:0007350 | inferred from sequence or structural similarity with UniProtKB:P23803 periodic partitioning by pair rule gene ; GO:0007366 | inferred from sequence or structural similarity with UniProtKB:P23803 negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:P23803 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with UniProtKB:P23803 phagocytosis ; GO:0006909 | inferred from mutant phenotype imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:P23803" nucleus ; GO:0005634 | inferred from sequence or structural similarity with odd "org1, CG3242, sob, Sob, SOB" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3242 11-Aug-17 DroID_v2017_08 "Drer\osr2, Drer\osr1" - "Cele\klf-1, Cele\C46E10.9, Cele\odd-1, Cele\odd-2" "Xtro\osr2, Xtro\osr1" "Mmus\Zbtb7c, Mmus\Zfp651, Mmus\Osr2, Mmus\Bcl6b, Mmus\Patz1, Mmus\Osr1, Mmus\Zbtb16" "Hsap\ZBTB2, Hsap\GFI1, Hsap\OSR1, Hsap\OSR2" " embryonic stage | stage 5 , embryonic stage | stage >=6 , embryonic stage | late , pupal stage , larval stage | third instar " " organism | pair rule

,

segment polarity , Malpighian tubule

, embryonic brain

, embryonic/larval proventriculus

, leg | restricted

, organism | 90-100% egg length

, ventral thoracic disc | restricted

, pharyngeal muscle

" visible "leg & adult cuticleptc-559.1,ventral thoracic disc,tarsal segment,sex comb,ectopic" DRSC00838 K 0.075971856 1.073307477 -0.441114411 -0.257540673 0.370294197 1.581410602 FBgn0013658 ms(2)neo3 ms(2)neo3 http://flybase.org/reports/FBgn0013658 - gene - - - ms(2)neo3 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0010552 l(2)03728 lethal (2) 03728 http://flybase.org/reports/FBgn0010552 - gene - - - l(2)03728 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265714 CG44521 - http://flybase.org/reports/FBgn0265714 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44521 - CG44521 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259582 GG01048 - http://flybase.org/reports/FBgn0259582 gene - - - GG01048 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible leg FBgn0015698 E(var)5 Enhancer of variegation 5 http://flybase.org/reports/FBgn0015698 - gene - - - E(var)5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031132 CG15450 - http://flybase.org/reports/FBgn0031132 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR002123" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002123 - CG15450 IPR002123:Phospholipid/glycerol acyltransferase CG15450 11-Aug-17 DroID_v2017_08 "Drer\gpat3, Drer\gpat4, Drer\aup1, Drer\agpat9l" - "Cele\acl-5, Cele\acl-4" "Xtro\gpat3, Xtro\gpat4" "Mmus\Gpat4, Mmus\Aup1, Mmus\Agpat9" "Hsap\GPAT3, Hsap\GPAT4, Hsap\AUP1" viable FBgn0062621 Mod(var)1173 Mod(var)1173 http://flybase.org/reports/FBgn0062621 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1173, Mod(var)1173" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0015489 l(2)46Cm lethal (2) 46Cm http://flybase.org/reports/FBgn0015489 - gene - - - "U, l(2)46Cm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060956 l(3)S034107b lethal (3) S034107b http://flybase.org/reports/FBgn0060956 gene - - - "0341/07, l(3)S034107b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262775 Su(E1)-I - http://flybase.org/reports/FBgn0262775 gene - - - Su(E1)-I - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026674 l(1)G0115 lethal (1) G0115 http://flybase.org/reports/FBgn0026674 - gene - - - l(1)G0115 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0058235 CG40235 - http://flybase.org/reports/FBgn0058235 protein_coding_gene - - - CG40235 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010048 Hirsute Hirsute http://flybase.org/reports/FBgn0010048 - gene - - - "Hirsute, Hi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "eye,ommatidium,macrochaeta" FBgn0038809 CG16953 - http://flybase.org/reports/FBgn0038809 protein_coding_gene - - - CG16953 - CG16953 11-Aug-17 DroID_v2017_08 - - Cele\F25E2.2 - - - "viable,fertile" FBgn0021958 l(2)k10210 lethal (2) k10210 http://flybase.org/reports/FBgn0021958 - gene - - - l(2)k10210 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038344 obe obelus http://flybase.org/reports/FBgn0038344 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 helicase activity ; GO:0004386 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000974 inferred from sequence or structural similarity with protein_id:CAA94089 adherens junction organization ; GO:0034332 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype centrosome localization ; GO:0051642 | inferred from mutant phenotype" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity with SGD:S000000974 inferred from sequence or structural similarity with protein_id:CAA94089 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000000974 inferred from sequence or structural similarity with protein_id:CAA94089 "cg5205, obe, CG5205" "IPR001650:Helicase, C-terminal, IPR004179:Sec63 domain, IPR011545:DEAD/DEAH box helicase domain, IPR014756:Immunoglobulin E-set, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR003593:AAA+ ATPase domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR000008:C2 domain" CG5205 11-Aug-17 DroID_v2017_08 "Drer\hfm1, Drer\ascc3, Drer\snrnp200" "Scer\SLH1, Scer\HFM1, Scer\BRR2" "Cele\snrp-200, Cele\Y54E2A.4" Xtro\snrnp200 "Mmus\Ascc3, Mmus\Snrnp200, Mmus\Hfm1" "Hsap\ASCC3, Hsap\SNRNP200, Hsap\HFM1" viable FBgn0260855 Sec22 Secretory 22 http://flybase.org/reports/FBgn0260855 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with SGD:S000004258 "vesicle fusion with Golgi apparatus ; GO:0048280 | inferred from biological aspect of ancestor with PANTHER:PTN000752040 vesicle fusion ; GO:0006906 | inferred from sequence or structural similarity with SGD:S000004258 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000004258 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with SGD:S000004258 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000752040 phagocytosis ; GO:0006909 | inferred from mutant phenotype" ER to Golgi transport vesicle membrane ; GO:0012507 | inferred from sequence or structural similarity with SGD:S000004258 Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity with SGD:S000004258 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with SGD:S000004258 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with SGD:S000004258 transport vesicle ; GO:0030133 | inferred from sequence or structural similarity SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000004258 "CG7359, SEC22, 34F3.8, EG:34F3.8, Sec22p, Sec22" "IPR001388:Synaptobrevin, IPR010908:Longin domain, IPR011012:Longin-like domain" CG7359 11-Aug-17 DroID_v2017_08 "Drer\vamp1, Drer\vamp8, Drer\zgc:92912, Drer\sec22bb, Drer\sec22a, Drer\sec22ba, Drer\sybl1, Drer\sec22c, Drer\vamp2" Scer\SEC22 "Cele\sec-22, Cele\vamp-7, Cele\vamp-8, Cele\snb-1" "Xtro\vamp2, Xtro\sec22a, Xtro\vamp1, Xtro\ykt6, Xtro\vamp4, Xtro\sec22b, Xtro\sec22c, Xtro\vamp3, Xtro\vamp7" "Mmus\Vamp7, Mmus\Sec22a, Mmus\Vamp2, Mmus\Vamp8, Mmus\Sec22b, Mmus\Sec22c, Mmus\Vamp1, Mmus\Vamp4, Mmus\Ykt6, Mmus\Vamp3" "Hsap\SEC22A, Hsap\YKT6, Hsap\SEC22C, Hsap\VAMP2, Hsap\VAMP3, Hsap\VAMP4, Hsap\VAMP1, Hsap\VAMP7, Hsap\VAMP8, Hsap\SEC22B" DRSC29297 EK -0.999714792 -1.366519866 -1.850992771 -0.058931736 0.248069619 1.540368177 FBgn0002972 nuc1 nucleoside auxotroph 1 http://flybase.org/reports/FBgn0002972 - gene - - - "pyr2-2, pyr2-1, nuc1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "auxotroph,recessive,maternal effect,fertile" FBgn0262613 CG43139 - http://flybase.org/reports/FBgn0262613 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43139, DMG4-MB6.chr3R.40.017" - CG43139 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036088 CG14152 - http://flybase.org/reports/FBgn0036088 protein_coding_gene - - - "CG14152, CT33755" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069344 T:nls-tra nuclear localisation signal of tra http://flybase.org/reports/FBgn0069344 engineered_tag - - - "T:nls-tra, T:nls5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264363 CG43815 - http://flybase.org/reports/FBgn0264363 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43815 - CG43815 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020843 l(2)21Be lethal (2) 21Be http://flybase.org/reports/FBgn0020843 - gene - - - "21Be, l(2)21Be" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038989 CG6937 - http://flybase.org/reports/FBgn0038989 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype - "cg6937, CG6937" IPR000504:RNA recognition motif domain CG6937 11-Aug-17 DroID_v2017_08 Drer\nifk Scer\NOP15 Cele\T04A8.6 Xtro\nifk "Mmus\Nifk, Mmus\Trcg1" Hsap\NIFK "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC16140 I -1.747777868 -0.626960932 -0.016507862 0.346426373 0.844744892 0.146825109 FBgn0011468 l(3)neo35 lethal (3) neo35 http://flybase.org/reports/FBgn0011468 - gene - - - l(3)neo35 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0052035 CG32035 - http://flybase.org/reports/FBgn0052035 protein_coding_gene - - - CG32035 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053710 CG33710 - http://flybase.org/reports/FBgn0053710 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs03f11, bs03f11.y1, CG33710" - CG33710 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000617 e(y)1 enhancer of yellow 1 http://flybase.org/reports/FBgn0000617 "FBgn0000620, FBgn0011302" protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Saf6 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VYX1 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with e(y)2 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000249331" positive regulation of transcription of Notch receptor target ; GO:0007221 | inferred from mutant phenotype histone H3 acetylation ; GO:0043966 | inferred from direct assay regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:17306 inferred from sequence or structural similarity with SGD:S000004849 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype transcription factor TFIID complex ; GO:0005669 | inferred from physical interaction with Taf4 inferred from physical interaction with Taf6 nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay RNA polymerase II transcription factor complex ; GO:0090575 | inferred from physical interaction with N inferred from physical interaction with Su(H) SAGA complex ; GO:0000124 | inferred from physical interaction with Ada3 inferred from physical interaction with Ada2b inferred from physical interaction with Spt3 transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:17306 inferred from sequence or structural similarity with SGD:S000004849 "e(y)1, dTAF[[II]]40, TAF[[II]]40, dmTAF9, Taf9, dmTaf9, TAF40/42, dTAF9, TFIID, taf40/e(y)1, TAF[[II]], TAF[II]40, TAF9, dTAFII42, dTAF42, TAFII40, dTAF[[II]]42, d40, TAF40/42/e(y)1, CG6474, TFIID 42, TAFII40(42), TAF[[II]]40/42, Taf40, TAF42, TAF[[II]]42, dTAF[[40]], TAF40, dme-TAFII40, Taf42, Taf[[II]]40, p42, e(y)[1], e(y)4, TFIID-p42, E(y)1, TafII40" "IPR003162:Transcription initiation factor TAFII31, IPR009072:Histone-fold" CG6474 11-Aug-17 DroID_v2017_08 Drer\taf9 Scer\TAF9 Cele\taf-9 Xtro\taf9b "Mmus\Ak6, Mmus\Taf9, Mmus\Taf9b" "Hsap\TAF9, Hsap\TAF9B" "female sterile,recessive,viable,visible,male,female fertile,wild-type" "ovary,oocyte,macrochaeta" DRSC25903 IK -1.580826258 1.844344247 -0.891277819 1.112974895 0.590057902 2.356003602 FBgn0033364 CG13747 - http://flybase.org/reports/FBgn0033364 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from sequence model "CG13747, dmCG13747" IPR031720:Protein of unknown function DUF4728 CG13747 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259257 C76 - http://flybase.org/reports/FBgn0259257 gene - - - C76 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin,chaeta,ectopic" FBgn0017448 CG2187 - http://flybase.org/reports/FBgn0017448 - protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "D3-100EF, anon-100EF-D3, CG2187, dSLC5A6" IPR001734:Sodium/solute symporter CG2187 11-Aug-17 DroID_v2017_08 "Drer\slc5a1, Drer\slc5a6b, Drer\LOC568338, Drer\slc5a3a, Drer\slc5a9, Drer\slc5a6a, Drer\slc5a8, Drer\slc5a5, Drer\slc5a2, Drer\slc5a8l, Drer\slc5a12, Drer\si:dkeyp-9d4.5, Drer\slc5a11" Scer\DUR3 "Cele\ZK822.5, Cele\F52H2.4" "Xtro\slc5a9, Xtro\slc5a1.1, Xtro\slc5a8, Xtro\slc5a11, Xtro\slc5a2, Xtro\slc5a12, Xtro\slc5a5" "Mmus\Slc5a2, Mmus\Slc5a3, Mmus\Slc5a11, Mmus\Slc5a8, Mmus\Slc5a12, Mmus\Slc5a1, Mmus\Gm5134, Mmus\Slc5a4a, Mmus\Slc5a4b, Mmus\Slc5a9, Mmus\Slc5a5, Mmus\Slc5a10, Mmus\Slc5a6" "Hsap\SLC5A11, Hsap\SLC5A3, Hsap\SLC5A8, Hsap\SLC5A9, Hsap\SLC5A6, Hsap\SLC5A4, Hsap\SLC5A5, Hsap\SLC5A10, Hsap\SLC5A1, Hsap\SLC5A12, Hsap\SLC5A2" "partially lethal - majority die,some die during pupal stage" FBgn0036362 CG10725 - http://flybase.org/reports/FBgn0036362 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG10725 IPR002557:Chitin binding domain CG10725 11-Aug-17 DroID_v2017_08 - - Cele\dct-9 - - - viable FBgn0023514 CG14805 - http://flybase.org/reports/FBgn0023514 - protein_coding_gene - - - "i207, EG:63B12.7, CG14805" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site" CG14805 11-Aug-17 DroID_v2017_08 Drer\wdr18 Scer\IPI3 Cele\pro-1 Xtro\wdr18 Mmus\Wdr18 Hsap\WDR18 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0064174 l(2)T32 lethal (2) T32 http://flybase.org/reports/FBgn0064174 gene - - - l(2)T32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046652 anon-38D.12 anon-38D.12 http://flybase.org/reports/FBgn0046652 gene - - - "38D.12, anon-38D.12" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031682 CG5828 - http://flybase.org/reports/FBgn0031682 protein_coding_gene pantothenate kinase activity ; GO:0004594 | inferred from sequence or structural similarity with SGD:S000002939 coenzyme A biosynthetic process ; GO:0015937 | inferred from sequence or structural similarity with SGD:S000002939 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002939 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002939 CG5828 "IPR002791:Domain of unknown function DUF89, IPR016949:Uncharacterised conserved protein UCP030210" CG5828 11-Aug-17 DroID_v2017_08 "Drer\pank1a, Drer\pank1b, Drer\pank2, Drer\pank4" Scer\CAB1 "Cele\pnk-4, Cele\pnk-1" "Xtro\pank3, Xtro\pank4" "Mmus\Pank2, Mmus\Pank4, Mmus\Pank3, Mmus\Pank1" "Hsap\PANK1, Hsap\PANK2, Hsap\PANK3, Hsap\PANK4" viable FBgn0086390 BG01909 - http://flybase.org/reports/FBgn0086390 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - BG01909 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective,behavior defective,recessive" FBgn0031517 CG15406 - http://flybase.org/reports/FBgn0031517 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG15406 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG15406 11-Aug-17 DroID_v2017_08 "Drer\slc2a12, Drer\slc2a8, Drer\slc2a13b, Drer\slc2a6, Drer\slc2a10, Drer\LOC101882338" "Scer\YDL199C, Scer\YDR387C, Scer\VBA4, Scer\STL1, Scer\HXT1, Scer\ITR1, Scer\HXT4, Scer\HXT6, Scer\VBA1, Scer\HXT16, Scer\HXT15, Scer\HXT9, Scer\MPH3, Scer\ITR2, Scer\ATR1, Scer\MAL11, Scer\HXT13, Scer\MPH2, Scer\VBA5, Scer\HXT3, Scer\AZR1, Scer\GEX1, Scer\HXT2, Scer\ENB1, Scer\VBA3, Scer\VBA2, Scer\SNF3, Scer\HXT5, Scer\HXT10, Scer\HXT8, Scer\YMR279C, Scer\GAL2, Scer\RGT2, Scer\SGE1, Scer\YFL040W, Scer\HXT14, Scer\MAL31, Scer\HXT17, Scer\GEX2, Scer\HXT7, Scer\HXT11" Cele\K09C4.4 "Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a12" "Mmus\Slc2a12, Mmus\Slc2a13, Mmus\Slc2a6, Mmus\Slc2a8, Mmus\Slc2a10" "Hsap\SLC2A10, Hsap\SLC2A6, Hsap\SLC2A12, Hsap\SLC2A8, Hsap\SLC2A13" "viable,fertile" FBgn0050187 CG30187 - http://flybase.org/reports/FBgn0050187 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "BcDNA:SD12357, CG30187" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family, IPR033116:Serine proteases, trypsin family, serine active site" CG30187 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030331 CG15221 - http://flybase.org/reports/FBgn0030331 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 CG15221 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG15221 11-Aug-17 DroID_v2017_08 "Drer\sv2bb, Drer\sv2ba, Drer\sv2, Drer\sv2c, Drer\sv2a" - Cele\svop-1 Xtro\sv2b "Mmus\Sv2a, Mmus\Sv2b, Mmus\Sv2c" "Hsap\SV2C, Hsap\SV2B, Hsap\SV2A" viable FBgn0005030 ef elfin http://flybase.org/reports/FBgn0005030 - gene - - - ef - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male sterile,visible,male,body color defective" "wing,adult thorax,adult abdomen,tergite" FBgn0262886 CR43241 - http://flybase.org/reports/FBgn0262886 non_protein_coding_gene - - - "CR43241, lincRNA.229" - CR43241 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0285911 Vps16A Vacuolar protein sorting 16A http://flybase.org/reports/FBgn0285911 protein_coding_gene syntaxin binding ; GO:0019905 | contributes_to inferred from physical interaction with Syx17 "lysosomal transport ; GO:0007041 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from genetic interaction with ema intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR006925, InterPro:IPR006926, InterPro:IPR016534 endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD_LOCUS:VPS16; SGD:S000005966 regulation of SNARE complex assembly ; GO:0035542 | inferred from sequence or structural similarity with SGD_LOCUS:VPS16; SGD:S000005966 endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype" HOPS complex ; GO:0030897 | inferred from sequence or structural similarity with SGD_LOCUS:VPS16; SGD:S000005966 CORVET complex ; GO:0033263 | inferred from sequence or structural similarity with SGD_LOCUS:VPS16; SGD:S000005966 endosome ; GO:0005768 | inferred from direct assay HOPS complex ; GO:0030897 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay autophagosome ; GO:0005776 | inferred from direct assay HOPS complex ; GO:0030897 | inferred from mutant phenotype "ma, Vps16A, CG8454, Vps16, dVps16A, DmVps16, vps16A, V16" "IPR006925:Vps16, C-terminal, IPR006926:Vps16, N-terminal, IPR016534:Vacuolar protein sorting-associated protein 16, IPR011990:Tetratricopeptide-like helical domain, IPR011042:Six-bladed beta-propeller, TolB-like" CG8454 11-Aug-17 DroID_v2017_08 Drer\vps16 Scer\VPS16 Cele\vps-16 Xtro\vps16 Mmus\Vps16 "Hsap\PTPRA, Hsap\VPS16" eye color defective "pigment cell,Malpighian tubule" FBgn0063387 snoRNA:U27:54Eb snoRNA:U27:54Eb http://flybase.org/reports/FBgn0063387 snoRNA_gene - - - "U27snoRNA, CR32900, snoRNA:U27:54Eb, DmSnR74/Z4, Dm_18S.009, Dm_18S.011" - CR32900 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267021 CR45465 - http://flybase.org/reports/FBgn0267021 non_protein_coding_gene - - - CR45465 - CR45465 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033528 trsn translin http://flybase.org/reports/FBgn0033528 protein_coding_gene "single-stranded DNA binding ; GO:0003697 | inferred from electronic annotation with InterPro:IPR033956 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR033956 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR002848, InterPro:IPR016068, InterPro:IPR016069 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:Q7JVK6 endoribonuclease activity ; GO:0004521 | inferred from direct assay" "RNA metabolic process ; GO:0016070 | inferred from electronic annotation with InterPro:IPR033956 RNA interference ; GO:0016246 | inferred from mutant phenotype negative regulation of circadian sleep/wake cycle, sleep ; GO:0042321 | inferred from mutant phenotype behavioral response to starvation ; GO:0042595 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000077815 "trsn, translin, CG11761, TB-RBP" "IPR002848:Translin family, IPR016068:Translin, N-terminal, IPR033956:Translin" CG11761 11-Aug-17 DroID_v2017_08 Drer\tsn - - Xtro\mllt4 Mmus\Tsn Hsap\TSN "viable,fertile,jump response defective,recessive" FBgn0024283 Su(hh)3A Suppressor of hedgehog 3A http://flybase.org/reports/FBgn0024283 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "S(hh)3A, Su(hh)3A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266944 CR45395 - http://flybase.org/reports/FBgn0266944 non_protein_coding_gene - - - "lincRNA.571, CR45395" - CR45395 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025886 ms(3)2033 ms(3)2033 http://flybase.org/reports/FBgn0025886 - gene - - - "TW-ms(3)2033, ms(3)2033" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0003083 pi pied http://flybase.org/reports/FBgn0003083 - gene - - - pi - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,visible,viable,reduced" "eye,ommatidium,wing,genitalia,male" FBgn0264495 gpp grappa http://flybase.org/reports/FBgn0264495 protein_coding_gene histone methyltransferase activity (H3-K79 specific) ; GO:0031151 | inferred from mutant phenotype chromatin silencing at telomere ; GO:0006348 | inferred from biological aspect of ancestor with PANTHER:PTN000485246 histone methylation ; GO:0016571 | inferred from mutant phenotype DNA damage checkpoint ; GO:0000077 | inferred from biological aspect of ancestor with PANTHER:PTN000485246 lateral inhibition ; GO:0046331 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | NOT inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:P26017 inferred from genetic interaction with UniProtKB:Q24459 inferred from genetic interaction with UniProtKB:Q9VB08 inferred from genetic interaction with UniProtKB:Q9VHA0 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000485246 histone H3-K79 methylation ; GO:0034729 | inferred from mutant phenotype positive regulation of gene silencing by miRNA ; GO:2000637 | inferred from mutant phenotype chromatin silencing at telomere ; GO:0006348 | inferred from mutant phenotype chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:P09087 regulation of transcription regulatory region DNA binding ; GO:2000677 | inferred from biological aspect of ancestor with PANTHER:PTN000485246 nucleus ; GO:0005634 | inferred from mutant phenotype histone methyltransferase complex ; GO:0035097 | inferred by curator from GO:0031151 "DOT1L, gpp, CG42803, CG10272, l(3)03342, dDOT1L, l(3)sA3484, BcDNA:SD05230, grp, anon-WO0118547.319, Gpp, CG33324, dDot1, 0732/14, l(3)S073214b" "IPR025789:Histone-lysine N-methyltransferase DOT1 domain, IPR030445:Histone H3-K79 methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR021169:Histone H3-K79 methyltransferase, metazoa" CG42803 11-Aug-17 DroID_v2017_08 Drer\dot1l Scer\DOT1 "Cele\dot-1.1, Cele\dot-1.2, Cele\dot-1.4, Cele\D1053.2, Cele\dot-1.5, Cele\dot-1.3" Xtro\dot1l Mmus\Dot1l Hsap\DOT1L FBgn0045055 fs(1)192 female sterile (1) 192 http://flybase.org/reports/FBgn0045055 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)192 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "ovary,egg" FBgn0061189 Ubx::Afra\Ubx Ubx::Afra\Ubx http://flybase.org/reports/FBgn0061189 engineered_fusion_gene - - - Ubx::Afra\Ubx - - 11-Aug-17 DroID_v2017_08 - - - - - - Keilin's organ FBgn0031590 CG3702 - http://flybase.org/reports/FBgn0031590 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000482304 "CG3702, cg3702" IPR008429:Cleft lip and palate transmembrane 1 CG3702 11-Aug-17 DroID_v2017_08 "Drer\clptm1, Drer\clptm1l" - "Cele\C36B7.6, Cele\R166.2, Cele\T13H5.8" "Xtro\clptm1, Xtro\clptm1l" "Mmus\Clptm1, Mmus\Clptm1l" "Hsap\CLPTM1, Hsap\CLPTM1L" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014167 fs(1)2Ca fs(1)2Ca http://flybase.org/reports/FBgn0014167 - gene - - - fs(1)2Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,egg" FBgn0004390 RasGAP1 Ras GTPase activating protein 1 http://flybase.org/reports/FBgn0004390 FBgn0005621 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from mutant phenotype "regulation of GTPase activity ; GO:0043087 | inferred from electronic annotation with InterPro:IPR001936, InterPro:IPR023152 anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | non-traceable author statement Ras protein signal transduction ; GO:0007265 | inferred from mutant phenotype positive regulation of R7 cell differentiation ; GO:0045678 | inferred from genetic interaction with alph imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 negative regulation of Ras protein signal transduction ; GO:0046580 | non-traceable author statement sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype" intrinsic component of the cytoplasmic side of the plasma membrane ; GO:0031235 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 plasma membrane ; GO:0005886 | inferred from direct assay "gap, CG6721, gap1, GAP1, Gap, Ras-GAP, mip, GAP, rI533, sxt, rasGAP, Gap1, Gap 1, RasGAP1, RasGAP, FBpp0076097, RasGap1" "IPR000008:C2 domain, IPR001562:Zinc finger, Btk motif, IPR001849:Pleckstrin homology domain, IPR001936:Ras GTPase-activating protein, IPR011993:PH domain-like, IPR008936:Rho GTPase activation protein, IPR015943:WD40/YVTN repeat-like-containing domain, IPR023152:Ras GTPase-activating protein, conserved site" CG6721 11-Aug-17 DroID_v2017_08 "Drer\LOC570938, Drer\rasa4, Drer\iqgap2, Drer\rasa2, Drer\rasa3, Drer\nf1b" "Scer\IRA2, Scer\BUD2, Scer\IRA1" Cele\gap-1 "Xtro\rasal1, Xtro\rasa2, Xtro\rasa3" "Mmus\Rasa4, Mmus\Iqgap2, Mmus\Rasal1, Mmus\Nf1, Mmus\Rasa3, Mmus\Rasa2" "Hsap\RASAL1, Hsap\RASA3, Hsap\IQGAP2, Hsap\NF1, Hsap\RASA2, Hsap\RASA4B, Hsap\RASA4" larval stage | third instar " central nervous system | restricted

, photoreceptor cell | presumptive

, dorsal mesothoracic disc

, ventral thoracic disc

, cone cell

, eye-antennal disc

" "visible,recessive,viable,neuroanatomy defective,lethal,maternal effect,dominant,wild-type,meiotic cell cycle defective,partially lethal - majority die,mitotic cell cycle defective" "ommatidium,photoreceptor cell R7,cone cell,chordotonal organ,eye,rhabdomere,wing,wing sensillum,wing vein,primary pigment cell,secondary pigment cell,tertiary pigment cell,chorion,dorsal appendage,embryonic epidermis,maternal effect,bract,supernumerary,embryonic dorsal epidermis,somatic clone,sex comb,ectopic,prothoracic tibial bract,mesothoracic tibial bract,metathoracic tibial bract,dorsal air sac primordium,mitosis & nuclear chromosome,anaphase & condensed nuclear chromosome,nuclear chromosome,heart primordium,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,cell autonomous,stage 5 embryo,gastrula embryo" DRSC11172 IE 1.921989288 -0.213625818 4.509579961 0.007740226 1.053263025 0.861942993 FBgn0034601 CG4286 - http://flybase.org/reports/FBgn0034601 protein_coding_gene - - - CG4286 - CG4286 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC04459 K 0.012773364 -0.518099351 -0.364364869 -1.388530871 -1.557798038 -0.612219891 FBgn0065972 kali kali http://flybase.org/reports/FBgn0065972 gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | traceable author statement cellular_component ; GO:0005575 | no biological data available kali - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,somatic clone" "embryonic/larval mushroom body,somatic clone" FBgn0021764 sdk sidekick http://flybase.org/reports/FBgn0021764 FBgn0064868 protein_coding_gene - compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype pigment cell differentiation ; GO:0050931 | inferred from mutant phenotype negative regulation of photoreceptor cell differentiation ; GO:0046533 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | non-traceable author statement perivitelline space ; GO:0098595 | inferred from direct assay "CT16627, EG:BACR19J1.1, CG5227, BcDNA:LD22322, BcDNA:RE63453, sdk" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR013106:Immunoglobulin V-set domain" CG5227 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-148f13.1, Drer\il12rb2, Drer\sdk1b, Drer\sdk1a, Drer\il12rb2l, Drer\dscama, Drer\csf3r, Drer\sdk2b, Drer\lifrb, Drer\dscaml1, Drer\il6st, Drer\osmr" - Cele\rig-4 "Xtro\csf3r, Xtro\osmr, Xtro\il6st, Xtro\lifr, Xtro\tnc, Xtro\dscaml1, Xtro\sdk2" "Mmus\Il31ra, Mmus\Lifr, Mmus\Fstl5, Mmus\Lepr, Mmus\Sdk1, Mmus\Sdk2, Mmus\Dscam, Mmus\Il12rb2, Mmus\Il6st, Mmus\Osmr, Mmus\Gpr165, Mmus\Dscaml1, Mmus\Csf3r" "Hsap\DSCAM, Hsap\FSTL5, Hsap\IL31RA, Hsap\SDK2, Hsap\IL12RB2, Hsap\LEPR, Hsap\DSCAML1, Hsap\OSMR, Hsap\LIFR, Hsap\CSF3R, Hsap\IL6ST, Hsap\SDK1" "visible,recessive,viable" "eye,photoreceptor,mystery cell,pigment cell,ommatidium,interommatidial bristle,lens,cone cell" FBgn0001567 l(1)20Ad lethal (1) 20Ad http://flybase.org/reports/FBgn0001567 - gene - - - l(1)20Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000018 abo abnormal oocyte http://flybase.org/reports/FBgn0000018 FBgn0032323 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "CG6093, abo, Abo" "IPR019138:De-etiolated protein 1, Det1" CG6093 11-Aug-17 DroID_v2017_08 Drer\det1 - - Xtro\det1 Mmus\Det1 Hsap\DET1 "viable,fertile,lethal,maternal effect,recessive,rescuable maternal effect,female sterile,suppressor of variegation,dominant,non-suppressor of variegation" "extended germ band embryo,embryonic head,embryonic/first instar larval cuticle" FBgn0003001 op opaque http://flybase.org/reports/FBgn0003001 - gene - - - op - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male,female,poor,male fertile,female fertile" wing FBgn0001212 hp humped http://flybase.org/reports/FBgn0001212 - gene - - - hp - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "scutoscutellar suture,adult thorax,macrochaeta" FBgn0084112 E-3c7 Enhancer on chromosome 3-complementation group c http://flybase.org/reports/FBgn0084112 gene - - - "E-3c, E-3c7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,lethal,recessive,developmental rate defective" chaeta FBgn0060565 l(3)S096515b lethal (3) S096515b http://flybase.org/reports/FBgn0060565 gene - - - "0965/15, l(3)S096515b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051669 tRNA:Gln-CTG-2-5 transfer RNA:Glutamine-CTG 2-5 http://flybase.org/reports/FBgn0051669 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002638.trna4-GlnCTG, tRNA:Q:CTG:AE002638-a, CR31669, chr2L.trna37-GlnCTG, tRNA:Gln-CTG-2-5, tRNA:CR31669, tRNA-Gln-CTG-2-5, CAG" - CR31669 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019691 l(3)69Ah lethal (3) 69Ah http://flybase.org/reports/FBgn0019691 - gene - - - "l(3)69Aa, l(3)69Ah" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264864 CR44055 - http://flybase.org/reports/FBgn0264864 non_protein_coding_gene - - - CR44055 - CR44055 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038631 CG7695 - http://flybase.org/reports/FBgn0038631 protein_coding_gene - - - CG7695 IPR002350:Kazal domain CG7695 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014925 anon-72ABi anon-72ABi http://flybase.org/reports/FBgn0014925 - gene - - - anon-72ABi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015428 l(1)1Fh lethal (1) 1Fh http://flybase.org/reports/FBgn0015428 - gene - - - "13-80, l(1)1Fh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053534 tRNA:Ala-AGC-2-4 transfer RNA:Alanine-AGC 2-4 http://flybase.org/reports/FBgn0053534 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna12-AlaAGC, tRNA:-?:90Cb, tRNA:A:AGC:AE002708-b, CR33534, tRNA[[Ala]], chr3R.trna18-AlaAGC, tRNA-Ala-AGC-2-4, tRNA:Ala-AGC-2-4, tRNA:CR33534, GCU" - CR33534 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034858 eIF2Bdelta eukaryotic translation initiation factor 2B subunit delta http://flybase.org/reports/FBgn0034858 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000003315 neurogenesis ; GO:0022008 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD:S000003315 translational initiation ; GO:0006413 | inferred from sequence or structural similarity eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000027918 cytosol ; GO:0005829 | inferred from sequence or structural similarity eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity with SGD:S000003315 "CG10315, eIF2Bdelta, eIF2B-delta" IPR000649:Initiation factor 2B-related CG10315 11-Aug-17 DroID_v2017_08 Drer\eif2b4 Scer\GCD2 Cele\F11A3.2 Xtro\eif2b4 Mmus\Eif2b4 Hsap\EIF2B4 "lethal - all die before end of pupal stage,some die during pupal stage,lethal,neuroanatomy defective,visible,partially lethal - majority die" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,supernumerary,mesothoracic tergum" FBgn0052524 CG32524 - http://flybase.org/reports/FBgn0052524 protein_coding_gene - - - CG32524 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001399 l(1)2Fb lethal (1) 2Fb http://flybase.org/reports/FBgn0001399 - gene - - - "l68, JC155, N9, VA172, N4, l(1)N9, l(1)N6, l(1)2Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0031592 Art2 Arginine methyltransferase 2 http://flybase.org/reports/FBgn0031592 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR025799 peptidyl-arginine methylation ; GO:0018216 | inferred from sequence or structural similarity with HGNC:5187 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:5187 "DART2, CG3675, Art2, Dart2" "IPR025799:Protein arginine N-methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG3675 11-Aug-17 DroID_v2017_08 "Drer\prmt3, Drer\prmt1, Drer\prmt8b, Drer\prmt6, Drer\LOC556054, Drer\prmt2" Scer\HMT1 Cele\prmt-1 "Xtro\prmt6, Xtro\prmt8, Xtro\prmt1, Xtro\prmt3" "Mmus\Prmt8, Mmus\Prmt3, Mmus\Prmt6, Mmus\Prmt2, Mmus\Prmt1" "Hsap\PRMT8, Hsap\PRMT2, Hsap\PRMT3, Hsap\PRMT6, Hsap\PRMT1" viable FBgn0042178 CG32165 - http://flybase.org/reports/FBgn0042178 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "protein import into nucleus, translocation ; GO:0000060 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 ribosomal protein import into nucleus ; GO:0006610 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN000055427" nuclear periphery ; GO:0034399 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "CG18218, CG18861, anon-73Bb, CG32165, Imp4/5" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG32165 11-Aug-17 DroID_v2017_08 Drer\ipo4 Scer\KAP123 - Xtro\ipo4 Mmus\Ipo4 Hsap\IPO4 "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0001610 l(1)dd2 lethal (1) discs degenerate 2 http://flybase.org/reports/FBgn0001610 - gene - - - "l(1)d.degII, l(1)d.deg.2, l(1)d.deg.-2, l(1)dd2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" imaginal disc FBgn0032008 CG14277 - http://flybase.org/reports/FBgn0032008 protein_coding_gene - - - CG14277 - CG14277 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027297 l(1)G0143 lethal (1) G0143 http://flybase.org/reports/FBgn0027297 - gene - - - l(1)G0143 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" third instar larva FBgn0053108 CG33108 - http://flybase.org/reports/FBgn0053108 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG5926, BcDNA:RE26840, CG33108, C19orf54Nt" - CG33108 11-Aug-17 DroID_v2017_08 "Drer\zgc:153119, Drer\lsm3" - "Cele\lsm-3, Cele\K07A1.3" "Xtro\c19orf54, Xtro\lsm3" "Mmus\Lsm3, Mmus\BC024978" "Hsap\C19orf54, Hsap\LSM3" "viable,fertile,body color defective" mesothoracic tergum FBgn0267743 CR46074 - http://flybase.org/reports/FBgn0267743 non_protein_coding_gene - - - CR46074 - CR46074 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025390 Mur2B Mucin related 2B http://flybase.org/reports/FBgn0025390 FBgn0025389 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model chorion ; GO:0042600 | inferred from direct assay "EG:56G7.1, Mur2B, CG14796" IPR002557:Chitin binding domain CG14796 11-Aug-17 DroID_v2017_08 "Drer\asic2, Drer\otogl, Drer\vwf, Drer\scospondin, Drer\LOC799643" "Scer\FIG2, Scer\HPF1, Scer\MSB2, Scer\PRM7, Scer\YMR317W, Scer\FLO1, Scer\FLO5, Scer\FLO9, Scer\YIL169C, Scer\FLO11, Scer\HKR1" "Cele\srap-1, Cele\clec-223, Cele\H02F09.3, Cele\ZC178.2, Cele\H43E16.1, Cele\dpy-6, Cele\dct-9" - "Mmus\Vwf, Mmus\Muc6, Mmus\Emsy, Mmus\Sspo, Mmus\Muc5ac, Mmus\Muc2, Mmus\Muc5b, Mmus\Muc4" "Hsap\MUC16, Hsap\MUC17, Hsap\MUC5B, Hsap\SSPO, Hsap\MUC4, Hsap\MUC19, Hsap\MUC2, Hsap\OTOG, Hsap\MUC6, Hsap\VWF" FBgn0260352 GSd428 - http://flybase.org/reports/FBgn0260352 gene - - - GSd428 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0084017 CR41454 - http://flybase.org/reports/FBgn0084017 pseudogene_attribute - - - "CG41454, CR41454" - CR41454 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037322 Or83a Odorant receptor 83a http://flybase.org/reports/FBgn0037322 protein_coding_gene olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 sensory perception of smell ; GO:0007608 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 neuronal cell body ; GO:0043025 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "83a, DOR44, 83A.1, CG10612, Or83a" "IPR004117:Olfactory receptor, insect" CG10612 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032694 MESR3 Misexpression suppressor of ras 3 http://flybase.org/reports/FBgn0032694 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr cellular_component ; GO:0005575 | no biological data available "CG15162, MESR3" IPR011993:PH domain-like CG15162 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036537 CG18081 - http://flybase.org/reports/FBgn0036537 protein_coding_gene - - - "BcDNA:RE63284, CG18081" "IPR026939:At2g23090-like, IPR007513:Uncharacterised protein family SERF" CG18081 11-Aug-17 DroID_v2017_08 "Drer\znf706, Drer\zgc:91910" - "Cele\C01F6.9, Cele\K10B3.1" "Xtro\znf706.2, Xtro\znf706" Mmus\Zfp706 Hsap\ZNF706 FBgn0266907 CR45367 - http://flybase.org/reports/FBgn0266907 non_protein_coding_gene - - - CR45367 - CR45367 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065888 l(2)SH0225 lethal (2) SH0225 http://flybase.org/reports/FBgn0065888 gene - - - "l(2)SH0225, l(2)SH2 0225" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263521 mir-4969 mir-4969 stem loop http://flybase.org/reports/FBgn0263521 miRNA_gene - - - "mir-4969, dme-mir-4969, CR43506, miR-4969" - CR43506 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265663 CR44470 - http://flybase.org/reports/FBgn0265663 non_protein_coding_gene - - - "lincRNA.938, CR44470" - CR44470 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265188 CG44253 - http://flybase.org/reports/FBgn0265188 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG30194, CG44253" - CG44253 11-Aug-17 DroID_v2017_08 - - "Cele\acs-20, Cele\acs-12" - Mmus\Slc27a4 Hsap\SLC27A4 FBgn0032329 Art8 Arginine methyltransferase 8 http://flybase.org/reports/FBgn0032329 protein_coding_gene histone methyltransferase activity (H3-R2 specific) ; GO:0070611 | inferred from direct assay peptidyl-arginine N-methylation ; GO:0035246 | inferred from direct assay histone H3-R2 methylation ; GO:0034970 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DART8, CG16840, Art8, dART8, Dart8" "IPR025799:Protein arginine N-methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG16840 11-Aug-17 DroID_v2017_08 "Drer\prmt1, Drer\prmt8b, Drer\prmt3, Drer\prmt2, Drer\prmt6, Drer\LOC556054" Scer\HMT1 - "Xtro\prmt8, Xtro\prmt6, Xtro\prmt3, Xtro\prmt1" "Mmus\Prmt1, Mmus\Prmt3, Mmus\Prmt2, Mmus\Prmt8, Mmus\Prmt6" "Hsap\PRMT2, Hsap\PRMT3, Hsap\PRMT8, Hsap\PRMT1, Hsap\PRMT6" viable FBgn0000804 fs(1)de15 female sterile (1) defective eggs 15 http://flybase.org/reports/FBgn0000804 - gene - - - "de15, fs(1)de15" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "dorsal appendage,chorion,endochorion" FBgn0022705 Ca-2 Carbonic anhydrase-2 http://flybase.org/reports/FBgn0022705 - gene - - - "CA-2, Ca-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019882 anon-69Aa anon-69Aa http://flybase.org/reports/FBgn0019882 - gene - - - anon-69Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0044120 E(rst)B80 E(rst)B80 http://flybase.org/reports/FBgn0044120 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B80, E(rst)B80" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260610 2L3011 - http://flybase.org/reports/FBgn0260610 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3011 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0000828 fs(1)A147 female sterile (1) A147 http://flybase.org/reports/FBgn0000828 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)M5, fs(1)147, fs(1)A147" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" egg FBgn0020850 idr indora http://flybase.org/reports/FBgn0020850 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "#098, idr" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile ovary FBgn0003464 sol small optic lobes http://flybase.org/reports/FBgn0003464 FBgn0031175 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | inferred from sequence or structural similarity with UniProtKB:Q11002 calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | inferred from biological aspect of ancestor with PANTHER:PTN000021568 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000021568 temperature compensation of the circadian clock ; GO:0010378 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence or structural similarity with UniProtKB:Q11002 cytoplasm ; GO:0005737 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000021568 intracellular ; GO:0005622 | inferred from sequence or structural similarity with UniProtKB:Q11002 "SOL, CalpD, DmSol, w5000, nofE, PC79, CG1391, sol, Sol" "IPR000169:Cysteine peptidase, cysteine active site, IPR001300:Peptidase C2, calpain, catalytic domain, IPR001876:Zinc finger, RanBP2-type, IPR022684:Peptidase C2, calpain family" CG1391 11-Aug-17 DroID_v2017_08 "Drer\zgc:136872, Drer\capn3a, Drer\adgb, Drer\capn15, Drer\capn1b, Drer\capn2l, Drer\capn10, Drer\capn9, Drer\si:ch211-202f3.3, Drer\zgc:55262, Drer\capn5a, Drer\si:dkeyp-50d11.2, Drer\zgc:85932, Drer\capn3b, Drer\zgc:162184, Drer\capn12, Drer\zgc:92480, Drer\si:ch211-202f3.4, Drer\capn2b, Drer\capn5b, Drer\capn1a, Drer\si:dkey-19b23.13" Scer\RIM13 "Cele\W05G11.4, Cele\F44F1.3, Cele\W04A4.4, Cele\F47F6.9, Cele\T11A5.6" "Xtro\capn9, Xtro\LOC100497805, Xtro\capn7, Xtro\capn1, Xtro\LOC100494922, Xtro\capn15, Xtro\capn6, Xtro\capn2.2, Xtro\capn13, Xtro\capn3, Xtro\capn10, Xtro\capn8" "Mmus\Capn5, Mmus\Capn13, Mmus\Capn6, Mmus\Capn1, Mmus\Capn2, Mmus\Capn12, Mmus\Capn10, Mmus\Capn7, Mmus\Capn9, Mmus\Capn3, Mmus\Capn15, Mmus\Adgb, Mmus\Capn8, Mmus\Capn11" "Hsap\CAPN12, Hsap\CAPN8, Hsap\CAPN3, Hsap\CAPN1, Hsap\CAPN10, Hsap\CAPN11, Hsap\CAPN13, Hsap\CAPN14, Hsap\CAPN9, Hsap\CAPN6, Hsap\ADGB, Hsap\CAPN7, Hsap\CAPN5, Hsap\CAPN2, Hsap\CAPN15" "flight defective,behavior defective,wild-type,viable,neuroanatomy defective,recessive,visual behavior defective" "optic lobe,cell body rind of medulla,Pdf neuron,medulla neuropil,cell body rind of lobula plate,lobula,embryonic/larval optic stalk,lobula plate,central nervous system,adult central nervous system" DRSC20587 I 0.292935429 2.057455565 0.450934372 -0.444434464 -0.716599211 -0.669287331 FBgn0013701 mt:tRNA:Asn-GTT mitochondrial transfer RNA:Asparagine-GTT http://flybase.org/reports/FBgn0013701 FBgn0002867 tRNA_gene - - - "CR34079, tRNA[Asn], mtdbD00006304, mt:tRNA:Asn-GTT, mt:tRNA:N" - CR34079 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085482 CG34453 - http://flybase.org/reports/FBgn0085482 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34453, CG34018, BP1026" - CG34453 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002592 E(spl)m2-BFM "Enhancer of split m2, Bearded family member" http://flybase.org/reports/FBgn0002592 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory organ development ; GO:0007423 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from sequence or structural similarity with Brd cell fate specification ; GO:0001708 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG6104, HLHm2, E(spl)m2, m2, E(Spl)m2, E(spl), DmelCG6104, E(spl)m2-BFM" IPR029686:Enhancer of split M4 family CG6104 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | third instar , embryonic stage | stage 9 , embryonic stage , embryonic stage | stage 10,11 , embryonic stage | 14-20 hr " " eye disc

, ventral neurogenic region

, mesoderm | presumptive

, morphogenetic furrow | posterior to

, dorsal mesothoracic disc | restricted

, morphogenetic furrow | vicinity of

, proneural cluster &&of dorsal mesothoracic disc

, proneural cluster

" "visible,lethal - all die before end of pupal stage,some die during pupal stage" "sensory mother cell,wing vein L5,anterior dorsocentral bristle,posterior dorsocentral bristle,macrochaeta & adult head-537.4,macrochaeta & mesothoracic tergum-537.4,microchaeta" FBgn0025755 l(3)93DFg lethal (3) 93DFg http://flybase.org/reports/FBgn0025755 - gene - - - l(3)93DFg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039764 CG15535 - http://flybase.org/reports/FBgn0039764 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15535 IPR013730:Fyv7/TAP26 CG15535 11-Aug-17 DroID_v2017_08 Drer\ccdc59 - Cele\F10E9.11 Xtro\ccdc59 Mmus\Ccdc59 Hsap\CCDC59 viable FBgn0020335 anon-66BCa anon-66BCa http://flybase.org/reports/FBgn0020335 - gene - - - "7F10, anon-66BCa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267247 CR45687 - http://flybase.org/reports/FBgn0267247 non_protein_coding_gene - - - CR45687 - CR45687 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022072 l(2)k07803 lethal (2) k07803 http://flybase.org/reports/FBgn0022072 - gene - - - l(2)k07803 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053125 CG33125 - http://flybase.org/reports/FBgn0053125 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33125 - CG33125 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026312 Y56 Y56 http://flybase.org/reports/FBgn0026312 - gene - - cellular_component ; GO:0005575 | no biological data available Y56 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038003 CG3916 - http://flybase.org/reports/FBgn0038003 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP154, CG3916" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG3916 11-Aug-17 DroID_v2017_08 "Drer\zgc:92745, Drer\zgc:112302, Drer\zgc:112368, Drer\st14b, Drer\prss59.2, Drer\zgc:112266, Drer\prss59.1, Drer\zgc:92041" - "Cele\try-3, Cele\try-1, Cele\svh-1" - "Mmus\Ctsg, Mmus\Ovch2" "Hsap\OVCH1, Hsap\OVCH2" viable FBgn0035553 CG13722 - http://flybase.org/reports/FBgn0035553 protein_coding_gene - - - CG13722 - CG13722 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC24663 K -0.053723364 0.108946896 0.488694115 0.704372612 2.26357354 -0.539041499 FBgn0066069 Su(var)2-7 Su(var)2-7 http://flybase.org/reports/FBgn0066069 gene - - - Su(var)2-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265540 CR44390 - http://flybase.org/reports/FBgn0265540 non_protein_coding_gene - - - CR44390 - CR44390 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041252 Femcoat Femcoat http://flybase.org/reports/FBgn0041252 protein_coding_gene structural constituent of chorion ; GO:0005213 | non-traceable author statement eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG15573, Femcoat, femcoat" - CG15573 11-Aug-17 DroID_v2017_08 - - - - - - viable "endochorion,exochorion" FBgn0022626 Dia6 Diaphorase 6 http://flybase.org/reports/FBgn0022626 - gene - - - "DIA-6, Dia6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016936 smi79E smell impaired 79E http://flybase.org/reports/FBgn0016936 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi79E - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive" FBgn0266785 CR45250 - http://flybase.org/reports/FBgn0266785 non_protein_coding_gene - - - CR45250 - CR45250 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267874 CR46162 - http://flybase.org/reports/FBgn0267874 pseudogene_attribute - - - "CR46162, CG12717-related" - CR46162 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036924 hale hale-bopp http://flybase.org/reports/FBgn0036924 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7570, hale" - CG7570 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0259634 B1508 - http://flybase.org/reports/FBgn0259634 gene - - - B1508 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,antennal segment,arista" FBgn0266237 CR44932 - http://flybase.org/reports/FBgn0266237 non_protein_coding_gene - - - "CR44932, lincRNA.700" - CR44932 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050399 CR30399 - http://flybase.org/reports/FBgn0050399 non_protein_coding_gene - - - CR30399 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037109 MED1 Mediator complex subunit 1 http://flybase.org/reports/FBgn0037109 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR019680 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred by curator from GO:0016592 mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred by curator from GO:0006366 mediator complex ; GO:0016592 | inferred from mutant phenotype "Med1, Trap220, Med1/SOP3/TRAP220, dTRAP220, CG7162, MED1, FBgn0037109" "IPR019680:Mediator complex, subunit Med1" CG7162 11-Aug-17 DroID_v2017_08 "Drer\zgc:111976, Drer\med1" - - Xtro\med1 Mmus\Med1 Hsap\MED1 "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0038223 Afti Aftiphilin http://flybase.org/reports/FBgn0038223 protein_coding_gene "protein transporter activity ; GO:0008565 | inferred from mutant phenotype AP-1 adaptor complex binding ; GO:0035650 | inferred from physical interaction with AP-1μ, AP-1γ" intracellular transport ; GO:0046907 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype trans-Golgi network membrane ; GO:0032588 | inferred from direct assay "CG8538, Afti, dAfti" "IPR029205:Aftiphilin, clathrin-binding box" CG8538 11-Aug-17 DroID_v2017_08 "Drer\aftpha, Drer\aftphb" - Cele\Y45G5AM.9 Xtro\aftph "Mmus\BC022687, Mmus\Aftph" "Hsap\AFTPH, Hsap\C14orf79" "size defective,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,visible,partially lethal - majority die" "eye,ommatidium,trichogen cell,mesothoracic tergum" FBgn0069913 CG4681 - http://flybase.org/reports/FBgn0069913 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.29, CG4681" - CG4681 11-Aug-17 DroID_v2017_08 Drer\tex9 - - Xtro\tex9 Mmus\Tex9 Hsap\TEX9 "partially lethal - majority die,some die during pupal stage" FBgn0010197 Gyc32E Guanyl cyclase at 32E http://flybase.org/reports/FBgn0010197 FBgn0053114 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 guanylate cyclase activity ; GO:0004383 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 receptor activity ; GO:0004872 | inferred from sequence or structural similarity with Gyc76C protein kinase activity ; GO:0004672 | NOT inferred from key residues guanylate cyclase activity ; GO:0004383 | inferred from sequence or structural similarity with Gyc76C receptor activity ; GO:0004872 | non-traceable author statement cGMP biosynthetic process ; GO:0006182 | non-traceable author statement cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 cGMP-mediated signaling ; GO:0019934 | inferred from sequence or structural similarity with Gyc76C protein phosphorylation ; GO:0006468 | NOT inferred from key residues signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 "integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Gyc76C plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 integral component of plasma membrane ; GO:0005887 | non-traceable author statement guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "GYC 32E, CG6275, DMRGC, GC, Gyc-r, Cyg1, CG33114, Gyc32E" "IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR000719:Protein kinase domain, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001828:Receptor, ligand binding region, IPR011009:Protein kinase-like domain, IPR029787:Nucleotide cyclase, IPR028082:Periplasmic binding protein-like I, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG33114 11-Aug-17 DroID_v2017_08 "Drer\gucy2c, Drer\npr2, Drer\npr1b, Drer\gc2, Drer\npr3, Drer\gucy2g, Drer\si:ch73-139e5.4, Drer\gc3, Drer\ints3, Drer\si:dkey-37g12.1, Drer\npr1a, Drer\gucy2f" Scer\CDC15 "Cele\gcy-20, Cele\gcy-4, Cele\gcy-27, Cele\gcy-29, Cele\gcy-5, Cele\gcy-15, Cele\gcy-13, Cele\gcy-6, Cele\gcy-17, Cele\daf-11, Cele\gcy-11, Cele\gcy-2, Cele\Y92H12A.4, Cele\gcy-3, Cele\gcy-28, Cele\gcy-7, Cele\odr-1, Cele\gcy-9, Cele\gcy-8, Cele\gcy-25, Cele\gcy-19, Cele\gcy-22, Cele\gcy-14, Cele\gcy-21, Cele\gcy-23, Cele\gcy-1, Cele\gcy-12, Cele\gcy-18" "Xtro\npr1, Xtro\gucy2c, Xtro\gucy2d, Xtro\gucy2f, Xtro\npr3" "Mmus\Gucy2g, Mmus\Npr2, Mmus\Gucy2c, Mmus\Ints3, Mmus\Npr1, Mmus\Gucy2d, Mmus\Npr3, Mmus\Gucy2f, Mmus\Gucy2e" "Hsap\BUB1B-PAK6, Hsap\GUCY2C, Hsap\GUCY2F, Hsap\NPR3, Hsap\NPR1, Hsap\INTS3, Hsap\GUCY2D, Hsap\NPR2" " adult stage && oogenesis stage , adult stage , embryonic stage | early , larval stage , adult stage && oogenesis stage | stage S10 " " germarium

, adult head

, head

ubiquitous , nurse cell

" FBgn0019658 sAB1 sAB1 http://flybase.org/reports/FBgn0019658 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available sAB1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027597 CG17712 - http://flybase.org/reports/FBgn0027597 - protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR000683 - - "BcDNA:GH03377, CG17712" "IPR000683:Oxidoreductase, N-terminal, IPR016040:NAD(P)-binding domain" CG17712 11-Aug-17 DroID_v2017_08 "Drer\gfod2, Drer\zgc:101723, Drer\zgc:154075, Drer\si:ch211-276f18.2" "Scer\GAL80, Scer\YMR315W" "Cele\fbxc-36, Cele\fbxc-21" "Xtro\gfod2, Xtro\dhdh, Xtro\gfod1" "Mmus\Gfod2, Mmus\Dhdh, Mmus\Gfod1" "Hsap\GFOD1, Hsap\GFOD2" "viable,fertile,visible" trichogen cell FBgn0050241 tRNA:Leu-AAG-1-1 transfer RNA:Leucine-AAG 1-1 http://flybase.org/reports/FBgn0050241 tRNA_gene CUU codon-amino acid adaptor activity ; GO:0033417 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033417 cytosol ; GO:0005829 | inferred by curator from GO:0033417 "CR30241, AE002787.trna15-LeuAAG, tRNA:L:AAG:AE002787-b, chr2R.trna74-LeuAAG, tRNA-Leu-AAG-1-1, tRNA:Leu-AAG-1-1, tRNA:CR30241, CUU" - CR30241 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267605 CR45943 - http://flybase.org/reports/FBgn0267605 non_protein_coding_gene - - - CR45943 - CR45943 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037445 CG9727 - http://flybase.org/reports/FBgn0037445 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000289470 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000289470" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000289470 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000289470 CG9727 "IPR003150:DNA-binding RFX-type winged-helix domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG9727 11-Aug-17 DroID_v2017_08 "Drer\LOC100538179, Drer\rfx7, Drer\rfx5" Scer\RFX1 - "Xtro\rfx7, Xtro\rfx5" "Mmus\Rfx7, Mmus\Rfx5" "Hsap\RFX5, Hsap\RFX7" lethal FBgn0034268 CG4989 - http://flybase.org/reports/FBgn0034268 protein_coding_gene - - - CG4989 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034546 CG13442 - http://flybase.org/reports/FBgn0034546 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:23356 zinc ion binding ; GO:0008270 | inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:23356 endosome ; GO:0005768 | inferred from sequence or structural similarity with HGNC:23356 lysosome ; GO:0005764 | inferred from sequence or structural similarity with HGNC:23356 CG13442 "IPR011016:Zinc finger, RING-CH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033275:E3 ubiquitin-protein ligase MARCH-like" CG13442 11-Aug-17 DroID_v2017_08 "Drer\march9, Drer\march7, Drer\march11, Drer\march4, Drer\march6, Drer\zgc:153256, Drer\march8, Drer\march2, Drer\zgc:158785" Scer\SSM4 "Cele\marc-3, Cele\marc-1, Cele\marc-5, Cele\marc-4" "Xtro\march11, Xtro\march9, Xtro\march3, Xtro\march8, Xtro\march4, Xtro\march2, Xtro\march7, Xtro\march1" "Mmus\March3, Mmus\March9, Mmus\March4, Mmus\March1, Mmus\March10, Mmus\March11, Mmus\March8, Mmus\March6, Mmus\March2" "Hsap\MARCH2, Hsap\MARCH9, Hsap\MARCH10, Hsap\MARCH11, Hsap\MARCH6, Hsap\MARCH8, Hsap\MARCH7, Hsap\MARCH1, Hsap\MARCH3, Hsap\MARCH4" viable FBgn0037386 CG1208 - http://flybase.org/reports/FBgn0037386 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG1208 "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG1208 11-Aug-17 DroID_v2017_08 "Drer\slc2a6, Drer\si:ch1073-263o8.2, Drer\slc2a1a, Drer\LOC101882338, Drer\si:dkey-229d11.5, Drer\LOC797974, Drer\slc2a3a, Drer\slc2a12, Drer\slc2a13b, Drer\slc2a3b, Drer\slc2a10, Drer\slc2a1b, Drer\slc2a8" "Scer\SNF3, Scer\VBA1, Scer\HXT10, Scer\YDR387C, Scer\HXT16, Scer\YMR279C, Scer\VBA5, Scer\STL1, Scer\MPH2, Scer\HXT7, Scer\GAL2, Scer\HXT13, Scer\SGE1, Scer\AZR1, Scer\GEX2, Scer\HXT15, Scer\VBA3, Scer\YBR241C, Scer\HXT2, Scer\HXT11, Scer\VBA2, Scer\YDL199C, Scer\HXT1, Scer\VBA4, Scer\HXT14, Scer\ITR2, Scer\VPS73, Scer\ITR1, Scer\YFL040W, Scer\HXT3, Scer\HXT4, Scer\HXT17, Scer\ENB1, Scer\HXT6, Scer\GEX1, Scer\HXT9, Scer\MAL11, Scer\MAL31, Scer\HXT8, Scer\MPH3, Scer\RGT2, Scer\ATR1, Scer\HXT5" "Cele\M01G12.9, Cele\ZK829.9, Cele\Y66D12A.21, Cele\fgt-1, Cele\M01G12.14" "Xtro\slc2a10, Xtro\slc2a12, Xtro\slc2a6, Xtro\slc2a8" "Mmus\Pate4, Mmus\Slc2a10, Mmus\Slc2a12, Mmus\Slc2a13, Mmus\Slc2a8, Mmus\Gm5615, Mmus\Acrv1, Mmus\Gm17689, Mmus\Gm7257, Mmus\Slc2a4, Mmus\Pate1, Mmus\1700013H16Rik, Mmus\Slc2a3, Mmus\Slc2a1, Mmus\Tm2d1, Mmus\Slc2a6, Mmus\Pate3" "Hsap\SLC2A3, Hsap\SLC2A8, Hsap\SLC2A14, Hsap\SLC2A4, Hsap\ACRV1, Hsap\PATE1, Hsap\PATE3, Hsap\TM2D1, Hsap\SLC2A6, Hsap\SLC2A1, Hsap\PATE4, Hsap\SLC2A10, Hsap\SLC2A13, Hsap\SLC2A12" FBgn0022060 l(2)k08046 lethal (2) k08046 http://flybase.org/reports/FBgn0022060 - gene - - - l(2)k08046 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027556 CG4928 - http://flybase.org/reports/FBgn0027556 - protein_coding_gene potassium channel regulator activity ; GO:0015459 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 regulation of muscle contraction ; GO:0006937 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 regulation of potassium ion transport ; GO:0043266 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 striated muscle dense body ; GO:0055120 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q86WB7 "BcDNA:GH10120, CG4928" "IPR020846:Major facilitator superfamily domain, IPR010291:Ion channel regulatory protein, UNC-93" CG4928 11-Aug-17 DroID_v2017_08 "Drer\unc93a, Drer\unc93b1" - Cele\unc-93 "Xtro\unc93a, Xtro\unc93b1, Xtro\LOC100487981" "Mmus\Gm9992, Mmus\Unc93a, Mmus\Unc93b1" "Hsap\UNC93B1, Hsap\UNC93A" "viable,fertile,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0036686 CG7728 - http://flybase.org/reports/FBgn0036686 protein_coding_gene GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000304594 U3 snoRNA binding ; GO:0034511 | inferred from biological aspect of ancestor with PANTHER:PTN000304594 GTP binding ; GO:0005525 | inferred from biological aspect of ancestor with PANTHER:PTN000304594 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000304594 cellular response to starvation ; GO:0009267 | inferred from expression pattern endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000479 | inferred from biological aspect of ancestor with PANTHER:PTN000304594 neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012948 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000304595 CG7728 "IPR030387:Bms1/Tsr1-type G domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR007034:Ribosome biogenesis protein BMS1/TSR1, C-terminal, IPR012948:AARP2CN" CG7728 11-Aug-17 DroID_v2017_08 Drer\bms1 Scer\BMS1 Cele\Y61A9LA.10 Xtro\bms1 Mmus\Bms1 Hsap\BMS1 "lethal,neuroanatomy defective,partially lethal - majority die,visible,female semi-sterile,female sterile" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0027954 lim legs incomplete and malformed http://flybase.org/reports/FBgn0027954 gene - - - lim - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260355 GSd229 - http://flybase.org/reports/FBgn0260355 gene - - - GSd229 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0062602 Mod(var)1447 Mod(var)1447 http://flybase.org/reports/FBgn0062602 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1447, Mod(var)1447" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0262102 CG42855 - http://flybase.org/reports/FBgn0262102 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42855 - CG42855 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034618 CG9485 - http://flybase.org/reports/FBgn0034618 protein_coding_gene "4-alpha-glucanotransferase activity ; GO:0004134 | inferred from biological aspect of ancestor with PANTHER:PTN000060165 amylo-alpha-1,6-glucosidase activity ; GO:0004135 | inferred from biological aspect of ancestor with PANTHER:PTN000060165" glycogen biosynthetic process ; GO:0005978 | inferred from electronic annotation with InterPro:IPR006421 glycogen catabolic process ; GO:0005980 | inferred from biological aspect of ancestor with PANTHER:PTN000060165 - "FBgn0034618, BEST:GH22856, CG9485" "IPR006421:Glycogen debranching enzyme, metazoa, IPR008928:Six-hairpin glycosidase-like, IPR010401:Glycogen debranching enzyme, IPR017853:Glycoside hydrolase superfamily, IPR032792:Glycogen debranching enzyme, glucanotransferase domain, IPR032790:Glycogen debranching enzyme, C-terminal, IPR032788:Glycogen debranching enzyme, central domain, IPR029436:Eukaryotic glycogen debranching enzyme, N-terminal domain" CG9485 11-Aug-17 DroID_v2017_08 "Drer\aglb, Drer\agla, Drer\LOC101886684" Scer\GDB1 Cele\agl-1 Xtro\agl Mmus\Agl Hsap\AGL viable FBgn0012033 65F 65F http://flybase.org/reports/FBgn0012033 - gene - - - 65F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262483 Rbp RIM-binding protein http://flybase.org/reports/FBgn0262483 protein_coding_gene - neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype cytoskeleton of presynaptic active zone ; GO:0048788 | inferred from direct assay "CG14867, CG43073, DRBP, CG5143, CG5152, CG31302, Rbp, drbp, rbp, RBP" "IPR011990:Tetratricopeptide-like helical domain, IPR001452:SH3 domain, IPR003961:Fibronectin type III, IPR011511:Variant SH3 domain, IPR013783:Immunoglobulin-like fold" CG43073 11-Aug-17 DroID_v2017_08 "Drer\lamb4, Drer\rimbp2, Drer\si:ch211-105f12.2, Drer\si:ch73-287m6.1" Scer\RUD3 Cele\rimb-1 - "Mmus\Rimbp3, Mmus\Bzrap1, Mmus\Rimbp2" "Hsap\RIMBP3C, Hsap\RIMBP3, Hsap\TSPOAP1, Hsap\RIMBP2, Hsap\RIMBP3B" DRSC15724 IEK -3.787669555 -2.580382595 -1.649570194 -6.079083919 -1.392361671 2.231061613 FBgn0065880 l(2)SH0237 lethal (2) SH0237 http://flybase.net/reports/FBgn0065880.html gene l(2)SH2 0237 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0033690 EndoG Endonuclease G http://flybase.org/reports/FBgn0033690 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821 endoribonuclease activity ; GO:0004521 | inferred from direct assay endodeoxyribonuclease activity ; GO:0004520 | inferred from direct assay endodeoxyribonuclease activity ; GO:0004520 | inferred from sequence or structural similarity with UniProtKB:Q14249" DNA-dependent DNA replication ; GO:0006261 | inferred from sequence or structural similarity with UniProtKB:Q14249 spermatid development ; GO:0007286 | inferred from mutant phenotype apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 mitochondrion inheritance ; GO:0000001 | inferred from mutant phenotype ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q14249 "EndoG, CG8862, endoG, dEndoG" "IPR001604:DNA/RNA non-specific endonuclease, IPR018524:DNA/RNA non-specific endonuclease, active site, IPR020821:Extracellular Endonuclease, subunit A" CG8862 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000000699, Drer\LOC100333474, Drer\zgc:172339, Drer\LOC100332173, Drer\si:ch211-133n4.4, Drer\LOC103909050, Drer\si:dkey-85k7.10, Drer\endog, Drer\si:ch211-165i18.2, Drer\LOC103910196, Drer\zgc:158445" Scer\NUC1 Cele\cps-6 "Xtro\exog, Xtro\endog, Xtro\endod1" "Mmus\Endog, Mmus\Exog, Mmus\Endod1" "Hsap\ENDOD1, Hsap\ENDOG, Hsap\EXOG" "viable,fertile,decreased cell death" "spermatid,mitochondrial nucleoid,male germline cell,mitochondrial nucleoidBSC699)" FBgn0065924 l(2)SH0148 lethal (2) SH0148 http://flybase.net/reports/FBgn0065924.html gene l(2)SH2 0148 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0086213 wbf-2 - http://flybase.org/reports/FBgn0086213 gene - - - wbf-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000921 fs(1)ne8 female sterile (1) no eggs 8 http://flybase.org/reports/FBgn0000921 - gene - - - "ne8, fs(1)ne[8], fs(1)ne8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,female sterile germline-dependent" "endochorion,oocyte,dorsal appendage,chorion" FBgn0267248 CR45688 - http://flybase.org/reports/FBgn0267248 non_protein_coding_gene - - - CR45688 - CR45688 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026183 rets retiarius http://flybase.org/reports/FBgn0026183 - gene - - - "ret, rets" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,reduced,fertile,chemical sensitive" "adult cuticle,wing" FBgn0052793 CG32793 - http://flybase.org/reports/FBgn0052793 protein_coding_gene - - - "EG:100G7.2, EG:100G7.1, anon-3Cb, anon-3Ca, CG3591, CG18852, CG18089, CG32793" IPR011989:Armadillo-like helical CG32793 11-Aug-17 DroID_v2017_08 - - Cele\sdc-2 - - - "lethal - all die before end of pupal stage,some die during pupal stage,viable,visible" mesothoracic tergum FBgn0005144 l(2)DTS6 lethal (2) DTS6 http://flybase.org/reports/FBgn0005144 - gene - - - "DTS-L6, l(2)DTS6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,recessive" FBgn0044050 Ilp3 Insulin-like peptide 3 http://flybase.org/reports/FBgn0044050 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 sleep ; GO:0030431 | inferred from mutant phenotype female mating behavior ; GO:0060180 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | NOT inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "dILP-3, dilp3, dilp, dilp-3, DILP, Dilp, Dilp 3, DILP3, CG14167, Ilp3, Ilp, Dilp-3, ilp3, dILP3, Dilp3, Ilp-3, dIlp3, DILP-3, dipl3" "IPR016179:Insulin-like, IPR022352:Insulin family, IPR022353:Insulin, conserved site" CG14167 11-Aug-17 DroID_v2017_08 "Drer\igf3, Drer\igf1, Drer\ins, Drer\insb, Drer\igf2b, Drer\igf2a" - Cele\ins-1 "Xtro\igf1, Xtro\ins, Xtro\igf2, Xtro\igf3" "Mmus\Igf1, Mmus\Ins1, Mmus\Igf2, Mmus\Ins2" "Hsap\IGF1, Hsap\IGF2, Hsap\INS, Hsap\INS-IGF2" " larval stage | second instar-- L | third instar , larval stage | third instar " " larval brain | restricted

, larval brain | restricted

anterior & medial " "large body,viable,mating defective" FBgn0016951 tilH touch insensitive larva H http://flybase.org/reports/FBgn0016951 - gene - - - "line 75, tilH" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0022395 Hex1 Hexokinase 1 http://flybase.org/reports/FBgn0022395 - gene - - - "HK, HEX, HEX-1, Hex1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035696 Best2 Bestrophin 2 http://flybase.org/reports/FBgn0035696 protein_coding_gene chloride channel activity ; GO:0005254 | inferred from sequence or structural similarity with Best1 chloride transport ; GO:0006821 | inferred from sequence or structural similarity with Best1 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Best1 peroxisome ; GO:0005777 | inferred from direct assay "dbest2, CG10173, Best2, dBest2" "IPR000615:Bestrophin, IPR021134:Bestrophin/UPF0187" CG10173 11-Aug-17 DroID_v2017_08 "Drer\best1, Drer\best2, Drer\best4" - "Cele\best-21, Cele\best-17, Cele\best-20, Cele\C09B9.85, Cele\best-3, Cele\best-7, Cele\best-25, Cele\best-15, Cele\best-9, Cele\best-16, Cele\best-6, Cele\best-18, Cele\best-10, Cele\best-5, Cele\best-2, Cele\best-8, Cele\best-4, Cele\best-26, Cele\best-11, Cele\best-13, Cele\best-23, Cele\best-24, Cele\best-22, Cele\best-1, Cele\best-12, Cele\best-19, Cele\best-14" "Xtro\best2, Xtro\best1, Xtro\best3, Xtro\best4" "Mmus\Best3, Mmus\Best1, Mmus\Best2" "Hsap\BEST4, Hsap\BEST1, Hsap\BEST2, Hsap\BEST3" viable FBgn0046767 CR32489 - http://flybase.org/reports/FBgn0046767 non_protein_coding_gene - - - "BcDNA:LD42550, CR32489" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22955 IE 0.568399764 -1.508553708 2.006411859 0.155732412 0.170586894 -0.463360798 FBgn0053696 CNMaR CNMamide Receptor http://flybase.org/reports/FBgn0053696 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from sequence model neuropeptide receptor activity ; GO:0008188 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred by curator from GO:0008188" "CG33696, CG16726, CG32047, Dm CG33696, CNMaR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG33696 11-Aug-17 DroID_v2017_08 "Drer\gpr142, Drer\cckar" - "Cele\F16C3.1, Cele\M04G7.3, Cele\H09F14.1, Cele\F52D10.4, Cele\frpr-8, Cele\C24B5.1, Cele\F56A12.2" - "Mmus\Gpr139, Mmus\Tacr3" "Hsap\GPR139, Hsap\GPR18" viable FBgn0032813 PCNA2 Proliferating cell nuclear antigen 2 http://flybase.org/reports/FBgn0032813 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000730, InterPro:IPR022648, InterPro:IPR022649 DNA polymerase processivity factor activity ; GO:0030337 | inferred from electronic annotation with InterPro:IPR000730 DNA polymerase binding ; GO:0070182 | inferred from direct assay" "regulation of DNA replication ; GO:0006275 | inferred from electronic annotation with InterPro:IPR000730, InterPro:IPR022648, InterPro:IPR022649 protein homotrimerization ; GO:0070207 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "PCNA2, DmPCNA2, CG10262" "IPR000730:Proliferating cell nuclear antigen, PCNA, IPR022648:Proliferating cell nuclear antigen, PCNA, N-terminal, IPR022649:Proliferating cell nuclear antigen, PCNA, C-terminal, IPR022659:Proliferating cell nuclear antigen, PCNA, conserved site" CG10262 11-Aug-17 DroID_v2017_08 Drer\pcna Scer\POL30 Cele\pcn-1 Xtro\pcna Mmus\Pcna Hsap\PCNA "viable,fertile" DRSC02030 E -0.058695132 0.627974275 -1.630962365 0.285509151 -0.451659876 -0.645753217 FBgn0020645 Lcp65Aa Lcp65Aa http://flybase.org/reports/FBgn0020645 - protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence or structural similarity chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "DMLCP65a, Lcp-a, DCP4, CG7287, Lcp65Aa, DmelLCp65Aa" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG7287 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\F44F1.4, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0031907 CG5171 - http://flybase.org/reports/FBgn0031907 protein_coding_gene trehalose-phosphatase activity ; GO:0004805 | inferred from direct assay trehalose biosynthetic process ; GO:0005992 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 trehalose metabolism in response to stress ; GO:0070413 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 CG5171 "IPR003337:Trehalose-phosphatase, IPR006379:HAD-superfamily hydrolase, subfamily IIB, IPR023214:HAD-like domain" CG5171 11-Aug-17 DroID_v2017_08 - Scer\TPS2 Cele\tps-2 - - - FBgn0039709 Cad99C Cadherin 99C http://flybase.org/reports/FBgn0039709 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model myosin binding ; GO:0017022 | inferred from physical interaction with ck" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 tube morphogenesis ; GO:0035239 | inferred from mutant phenotype vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | non-traceable author statement follicle cell microvillus organization ; GO:0032529 | inferred from mutant phenotype calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity regulation of follicle cell microvillus length ; GO:0032533 | inferred from mutant phenotype mucosal immune response ; GO:0002385 | inferred from mutant phenotype inferred from genetic interaction with norpA cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype apical protein localization ; GO:0045176 | inferred from mutant phenotype wing disc anterior/posterior pattern formation ; GO:0048100 | NOT inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype calcium-mediated signaling ; GO:0019722 | inferred from genetic interaction with norpA positive regulation of clathrin-dependent endocytosis ; GO:2000370 | inferred from mutant phenotype endosome ; GO:0005768 | colocalizes_with inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity microvillus ; GO:0005902 | inferred from direct assay brush border membrane ; GO:0031526 | colocalizes_with inferred from direct assay integral component of plasma membrane ; GO:0005887 | non-traceable author statement "cad99C, CA-10, DCad99C, CG15511, CT4930, CT35624, CG7805, CG31009, Cad99C, Dm Cad99C, CG310034, Cad99c" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site" CG31009 11-Aug-17 DroID_v2017_08 "Drer\pcdh15b, Drer\cdhr5a, Drer\pcdh15a, Drer\cdh17, Drer\cdh16, Drer\cdh13, Drer\cdhr2, Drer\cdhr5b" - "Cele\cdh-8, Cele\cdh-5, Cele\cdh-3" Xtro\pcdh15 "Mmus\Pcdh15, Mmus\Cdhr2, Mmus\Cdh13, Mmus\Cdh17" "Hsap\CDHR2, Hsap\CDH13, Hsap\DCHS2, Hsap\CDH17, Hsap\PCDH15" "female semi-fertile,female semi-sterile,viable,female sterile,visible,partially lethal - majority die,some die during pupal stage" "vitelline membrane,follicle cell,somatic clone,microvillus | somatic clone,microvillus & follicle cellFRT.RnorCD2.Act5C,egg,microvillus & follicle cell, with Cad99C‘îcyt.UAS.TAvicGFP-EGFP, FRT.RnorCD2.Act5C,microvillus & follicle cell,microvillus & follicle cell, with Cad99C21-5/Cad99C21-6, FRT.RnorCD2.Act5C,trichogen cell,mesothoracic tergum" FBgn0037708 CG9386 - http://flybase.org/reports/FBgn0037708 protein_coding_gene tRNA (uracil) methyltransferase activity ; GO:0016300 | inferred from biological aspect of ancestor with PANTHER:PTN000476571 tRNA methylation ; GO:0030488 | inferred from biological aspect of ancestor with PANTHER:PTN000476571 - CG9386 IPR011671:tRNA (uracil-O(2)-)-methyltransferase CG9386 11-Aug-17 DroID_v2017_08 Drer\trmt44 Scer\TRM44 Cele\C23G10.7 Xtro\trmt44 Mmus\Trmt44 Hsap\TRMT44 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0002924 ncd non-claret disjunctional http://flybase.org/reports/FBgn0002924 FBgn0010880 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 protein homodimerization activity ; GO:0042803 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | non-traceable author statement microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" distributive segregation ; GO:0032837 | inferred from mutant phenotype inferred from genetic interaction with Axs microtubule bundle formation ; GO:0001578 | inferred from direct assay centrosome duplication ; GO:0051298 | inferred from mutant phenotype regulation of mitotic spindle assembly ; GO:1901673 | inferred from genetic interaction with SAK mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype mitotic centrosome separation ; GO:0007100 | inferred from mutant phenotype inferred from genetic interaction with Klp61F spindle assembly involved in female meiosis ; GO:0007056 | non-traceable author statement spindle organization ; GO:0007051 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype spindle assembly involved in meiosis ; GO:0090306 | inferred from mutant phenotype minus-end directed microtubule sliding ; GO:0031534 | inferred from direct assay microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity mRNA transport ; GO:0051028 | inferred from mutant phenotype inferred from genetic interaction with αTub67C mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype regulation of mitotic spindle elongation ; GO:0032888 | inferred from mutant phenotype spindle ; GO:0005819 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | colocalizes_with inferred from direct assay meiotic spindle ; GO:0072687 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity cortical microtubule cytoskeleton ; GO:0030981 | colocalizes_with inferred from direct assay kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 mitotic spindle microtubule ; GO:1990498 | inferred from direct assay "Ncd, CG7831, ndc, DmNCD, l(3)05884, DmNcd, ca, ca[nd], ncd, cd, NCD, KIF C1, KIFC1" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031852:Spindle pole body-associated protein Vik1/Cik1, microtubule binding domain" CG7831 11-Aug-17 DroID_v2017_08 "Drer\kifc1, Drer\si:dkey-96l17.6, Drer\kifc3, Drer\si:ch211-257p13.3, Drer\kif25" Scer\KAR3 "Cele\klp-15, Cele\klp-16, Cele\klp-17, Cele\klp-3" "Xtro\kifc3, Xtro\kifc1" "Mmus\Kifc1, Mmus\Kifc3, Mmus\Kifc5b, Mmus\Kifc2" "Hsap\KIFC3, Hsap\KIF25, Hsap\KIFC1, Hsap\KIFC2" " embryonic stage | early , oogenesis stage " polar body nucleus

"meiotic cell cycle defective,mitotic cell cycle defective,fertile,viable,partially lethal - majority die,recessive,lethal,wild-type,partially,semidominant,lethal - all die before end of embryonic stage,some die during embryonic stage,female" "meiosis II & spindle & egg,meiosis & nuclear chromosome & oocyte,spindle & oocyte,mitotic metaphase & spindle,mitotic anaphase & spindle,spindle,S2 cell-line,cytoplasmic microtubule,spindle | embryonic stage,oocyte,aster | embryonic stage,meiosis & nuclear chromosome,mitosis & nuclear chromosome,meiosis & nuclear chromosome | female,mitotic cell cycle,brain,spindle microtubule,astral microtubule,spindle pole" FBgn0033557 CG12325 - http://flybase.org/reports/FBgn0033557 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000458249 "neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000458249 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000458249 cellular response to starvation ; GO:0009267 | inferred from expression pattern" Pwp2p-containing subcomplex of 90S preribosome ; GO:0034388 | inferred from biological aspect of ancestor with PANTHER:PTN000458249 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000458249 CG12325 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011044:Quinoprotein amine dehydrogenase, beta chain-like, IPR027145:Periodic tryptophan protein 2, IPR020472:G-protein beta WD-40 repeat, IPR019775:WD40 repeat, conserved site, IPR007148:Small-subunit processome, Utp12" CG12325 11-Aug-17 DroID_v2017_08 Drer\pwp2h Scer\PWP2 "Cele\B0280.9, Cele\F55F8.3" Xtro\pwp2 Mmus\Pwp2 "Hsap\LOC102724159, Hsap\PWP2" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0065718 l(2)SH0575 lethal (2) SH0575 http://flybase.org/reports/FBgn0065718 gene - - - "l(2)SH0575, l(2)SH2 0575" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002551 lh late hatching http://flybase.org/reports/FBgn0002551 - gene - - - lh - - 11-Aug-17 DroID_v2017_08 - - - - - - visible FBgn0032015 Ostgamma Oligosaccharide transferase gamma subunit http://flybase.org/reports/FBgn0032015 protein_coding_gene dolichyl-diphosphooligosaccharide-protein glycotransferase activity ; GO:0004579 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000294174 protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from biological aspect of ancestor with PANTHER:PTN000294174 encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay oligosaccharyltransferase complex ; GO:0008250 | inferred from biological aspect of ancestor with PANTHER:PTN000294174 "Ostgamma, CG7830, MagT1, dMagT1, OST" "IPR012336:Thioredoxin-like fold, IPR021149:Oligosaccharyl transferase complex, subunit OST3/OST6" CG7830 11-Aug-17 DroID_v2017_08 "Drer\tusc3, Drer\magt1" "Scer\OST6, Scer\OST3" Cele\ZK686.3 "Xtro\tusc3, Xtro\magt1" "Mmus\Magt1, Mmus\Tusc3" "Hsap\MAGT1, Hsap\TUSC3" "viable,fertile,immune response defective,visible" trichogen cell FBgn0267761 CR46092 - http://flybase.org/reports/FBgn0267761 non_protein_coding_gene - - - CR46092 - CR46092 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264628 appaloosa appaloosa http://flybase.org/reports/FBgn0264628 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - appaloosa - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,macrochaeta,ectopic" FBgn0011189 l(1)296-14 lethal (1) 296-14 http://flybase.org/reports/FBgn0011189 FBgn0010201 gene - - - "296-14, l(1)296-14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264475 CR43883 - http://flybase.org/reports/FBgn0264475 non_protein_coding_gene - - - "CR43883, lincRNA.411" - CR43883 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069102 mus323 mutagen-sensitive 323 http://flybase.org/reports/FBgn0069102 gene - - - mus323 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0043983 Su(rst)E358 Su(rst)E358 http://flybase.org/reports/FBgn0043983 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E358, Su(rst)E358" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040367 CG11382 - http://flybase.org/reports/FBgn0040367 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "EG:BACR42I17.10, CG11382" - CG11382 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038532 CG14322 - http://flybase.org/reports/FBgn0038532 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000001308 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from biological aspect of ancestor with PANTHER:PTN001108256 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with SGD:S000001308 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000001308 CG14322 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat" CG14322 11-Aug-17 DroID_v2017_08 "Drer\fbxw11b, Drer\fbxw11a, Drer\znf106a, Drer\traf7" "Scer\CAF4, Scer\MDV1, Scer\MET30" - Xtro\traf7 "Mmus\Traf7, Mmus\Fbxw11" "Hsap\FBXW11, Hsap\TRAF7, Hsap\ZNF106" "viable,fertile" FBgn0011244 Hsp60B Heat shock protein 60B http://flybase.org/reports/FBgn0011244 "FBgn0031274, FBgn0044567" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002423, InterPro:IPR018370 unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P10809 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" protein refolding ; GO:0042026 | inferred from electronic annotation with InterPro:IPR001844 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:P10809 spermatid development ; GO:0007286 | inferred from mutant phenotype protein import into mitochondrial intermembrane space ; GO:0045041 | inferred from biological aspect of ancestor with PANTHER:PTN000143508 apoptotic mitochondrial changes ; GO:0008637 | inferred from biological aspect of ancestor with PANTHER:PTN000143510 protein refolding ; GO:0042026 | inferred from sequence or structural similarity chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 'de novo' protein folding ; GO:0006458 | inferred from sequence or structural similarity with UniProtKB:P10809 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000888029 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000143507 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P10809 "152031_at, hsp60B, ms(2)21D, ms(2)06619, CG2830, anon-WO0140519.61, Hsp60B, Hsp60b, Hsp64, Dm21D, HSP60B" "IPR018370:Chaperonin Cpn60, conserved site, IPR001844:Chaperonin Cpn60, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG2830 11-Aug-17 DroID_v2017_08 Drer\hspd1 "Scer\CCT4, Scer\TCM62, Scer\HSP60" "Cele\cct-4, Cele\hsp-60" Xtro\hspd1 "Mmus\Hspd1, Mmus\Cct4" Hsap\HSPD1 "male sterile,recessive,viable" FBgn0261700 CR42736 - http://flybase.org/reports/FBgn0261700 non_protein_coding_gene - - - "CG42736, CR42736" - CR42736 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263552 mir-4961 mir-4961 stem loop http://flybase.org/reports/FBgn0263552 miRNA_gene - - - "mir-4961, dme-mir-4961, CR43537" - CR43537 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264709 CR43978 - http://flybase.org/reports/FBgn0264709 non_protein_coding_gene - - - CR43978 - CR43978 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264356 8D2 - http://flybase.org/reports/FBgn0264356 gene - - - 8D2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "eye,somatic clone,antenna,ectopic" FBgn0039719 CG15515 - http://flybase.org/reports/FBgn0039719 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:RE21592, CG15515" IPR000618:Insect cuticle protein CG15515 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\math-34, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0002976 ob oblique http://flybase.org/reports/FBgn0002976 - gene - - - ob - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,partially,recessive" "wing,wing vein" FBgn0028240 l(3)S001717 lethal (3) S001717 http://flybase.org/reports/FBgn0028240 gene - - - "0017/17, l(3)S001717" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0001922 l(2)25Cc lethal (2) 25Cc http://flybase.org/reports/FBgn0001922 - gene - - - "jf17, l(2)jf17, l(2)25Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002086 l(2)52Da lethal (2) 52Da http://flybase.org/reports/FBgn0002086 - gene - - - "Group1, Group-1, l(2)52Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0042686 Tirant\gag Tirant element gag http://flybase.org/reports/FBgn0042686 transposable_element_gene - - - "ORF1, Tirant\gag, gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262984 CG43292 - http://flybase.org/reports/FBgn0262984 protein_coding_gene - - - "CG43292, mlncRNA66A2, lincRNA.463" - CG43292 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025625 Sik2 Salt-inducible kinase 2 http://flybase.org/reports/FBgn0025625 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:21680" protein phosphorylation ; GO:0006468 | non-traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:21680 response to starvation ; GO:0042594 | inferred from mutant phenotype cellular response to hormone stimulus ; GO:0032870 | inferred from biological aspect of ancestor with PANTHER:PTN001552066 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 "CG4290, EG:22E5.8, Sik2, SIK2, SIK" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR034672:Salt-Inducible kinase, catalytic domain" CG4290 11-Aug-17 DroID_v2017_08 "Drer\mark2a, Drer\mark3a, Drer\si:dkey-31m14.7, Drer\sik2b, Drer\LOC108179363, Drer\sik1, Drer\sik2a, Drer\mark2b, Drer\mark1, Drer\mark4a, Drer\mark3b, Drer\prkaa1" "Scer\PRR1, Scer\SNF1, Scer\KIN1, Scer\KIN2" Cele\kin-29 "Xtro\mark2, Xtro\sik2, Xtro\sik3, Xtro\mark3, Xtro\prkaa1, Xtro\prkaa2, Xtro\mark4" "Mmus\Gm4922, Mmus\Gm5174, Mmus\1810024B03Rik, Mmus\Smok3a, Mmus\Sik3, Mmus\Gm6729, Mmus\Sik2, Mmus\Gm10668, Mmus\Gm6176, Mmus\Mark4, Mmus\Gm6902, Mmus\Mark3, Mmus\Prkaa1, Mmus\Gm14147, Mmus\Mark2, Mmus\Mark1, Mmus\Sik1, Mmus\Gm7168, Mmus\Gm14151, Mmus\Smok2a, Mmus\Prkaa2, Mmus\Smok2b, Mmus\Smok3b, Mmus\Gm6882, Mmus\4921509C19Rik" "Hsap\LOC102724428, Hsap\PRKAA2, Hsap\MARK2, Hsap\PRKAA1, Hsap\MARK3, Hsap\MARK4, Hsap\SIK2, Hsap\SIK1, Hsap\SIK3, Hsap\MARK1" "stress response defective,viable,long lived,calorie restriction conditional" DRSC18522 K 0.04408985 0.497558746 0.039945376 0.213166089 -1.841019891 -0.224295464 FBgn0265876 CR44665 - http://flybase.org/reports/FBgn0265876 non_protein_coding_gene - - - CR44665 - CR44665 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005477 l(1)ts1075 lethal (1) ts1075 http://flybase.org/reports/FBgn0005477 - gene - - - l(1)ts1075 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0051514 CR31514 - http://flybase.org/reports/FBgn0051514 non_protein_coding_gene - - - "BcDNA:RE21847, CR31514" - CR31514 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040122 l(2)23CDf lethal (2) 23CDf http://flybase.org/reports/FBgn0040122 gene - - - l(2)23CDf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040670 e(y)2b enhancer of yellow 2b http://flybase.org/reports/FBgn0040670 protein_coding_gene "transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000282153 transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from sequence or structural similarity with e(y)2 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000282153" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with e(y)2 poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from biological aspect of ancestor with PANTHER:PTN000282153 histone deubiquitination ; GO:0016578 | inferred from biological aspect of ancestor with PANTHER:PTN000282153 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000282153 nuclear pore ; GO:0005643 | inferred from electronic annotation with InterPro:IPR018783 nucleus ; GO:0005634 | inferred from sequence or structural similarity with e(y)2 SAGA complex ; GO:0000124 | inferred from biological aspect of ancestor with PANTHER:PTN000282153 DUBm complex ; GO:0071819 | inferred from biological aspect of ancestor with PANTHER:PTN000282153 "e(y)2b, CG14612" "IPR018783:Transcription factor, enhancer of yellow 2" CG14612 11-Aug-17 DroID_v2017_08 Drer\eny2 Scer\SUS1 Cele\T01C3.2 Xtro\eny2 Mmus\Eny2 Hsap\ENY2 FBgn0036437 CG5048 - http://flybase.org/reports/FBgn0036437 protein_coding_gene chaperone binding ; GO:0051087 | inferred from sequence or structural similarity with MGI:MGI:1921958 flagellated sperm motility ; GO:0030317 | inferred from sequence or structural similarity with MGI:MGI:1921958 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:1921958 "anon-WO0140519.238, CG5048" "IPR008978:HSP20-like chaperone, IPR012981:PIH1 domain, IPR026697:PIH1 domain-containing protein 3" CG5048 11-Aug-17 DroID_v2017_08 Drer\pih1d3 - - Xtro\pih1d3 "Mmus\Pih1d3, Mmus\Pih1h3b" Hsap\PIH1D3 viable FBgn0002056 l(2)38Ab lethal (2) 38Ab http://flybase.org/reports/FBgn0002056 - gene - - - "l(2)A113, l(2)38Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267751 CR46082 - http://flybase.org/reports/FBgn0267751 non_protein_coding_gene - - - "CR46082, Mgn99934" - CR46082 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010463 l(2)00572 lethal (2) 00572 http://flybase.org/reports/FBgn0010463 - gene - - - l(2)00572 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060498 l(3)S107701 lethal (3) S107701 http://flybase.org/reports/FBgn0060498 gene - - - "1077/01, l(3)S107701" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0052365 CG32365 - http://flybase.org/reports/FBgn0052365 protein_coding_gene - - - "CG13683, CG8294, CG13682, CG32365" IPR011989:Armadillo-like helical CG32365 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0036228 obst-G obstructor-G http://flybase.org/reports/FBgn0036228 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "obst-G, CG9781" IPR002557:Chitin binding domain CG9781 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\dct-9, Cele\cpg-2" - - - viable FBgn0035906 GstO2 Glutathione S transferase O2 http://flybase.org/reports/FBgn0035906 protein_coding_gene "glutathione dehydrogenase (ascorbate) activity ; GO:0045174 | inferred from direct assay transferase activity, transferring sulfur-containing groups ; GO:0016782 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay glutathione transferase activity ; GO:0004364 | inferred from direct assay pyrimidodiazepine synthase activity ; GO:0004734 | NOT inferred from direct assay glutathione binding ; GO:0043295 | inferred from direct assay" defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype glutathione metabolic process ; GO:0006749 | inferred from direct assay negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG6673B, CG6673A, anon-EST:Posey29, CG6673-A, CG6673-B, CG6673, GstO2, DmGSTO1, gsto2, GSTO2, DmGSTO2a, DmGSTO2b, GSTO2a, GSTO2b" "IPR004045:Glutathione S-transferase, N-terminal, IPR005442:Glutathione S-transferase, omega-class, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG6673 11-Aug-17 DroID_v2017_08 "Drer\gsto2, Drer\gsto1, Drer\gstr" Scer\GTT2 "Cele\gsto-3, Cele\gsto-2, Cele\gst-44, Cele\gsto-1, Cele\C02D5.4" "Xtro\gsto1, Xtro\gsto2, Xtro\LOC100498493" "Mmus\Gsto2, Mmus\Gsto1" "Hsap\GSTO2, Hsap\GSTO1" "viable,fertile,chemical sensitive,short lived" FBgn0043553 Su(ro[DOM])923 Su(ro[DOM])923 http://flybase.org/reports/FBgn0043553 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])923 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053288 CG33288 - http://flybase.org/reports/FBgn0053288 protein_coding_gene - - - "CG33288, cg33288" "IPR000408:Regulator of chromosome condensation, RCC1, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG33288 11-Aug-17 DroID_v2017_08 "Drer\als2a, Drer\rcc2, Drer\sergef, Drer\herc1, Drer\rcbtb1, Drer\als2b, Drer\rccd1, Drer\rcbtb2, Drer\rpgrb, Drer\rcc1, Drer\ftr97, Drer\herc2, Drer\rpgra, Drer\wbscr16" "Scer\ATS1, Scer\FMP25, Scer\SRM1" Cele\W09G3.7 "Xtro\herc2, Xtro\als2cl, Xtro\nek9, Xtro\rcbtb1, Xtro\als2, Xtro\wbscr16, Xtro\rcbtb2, Xtro\herc1, Xtro\rcc1" "Mmus\Rcbtb1, Mmus\Herc2, Mmus\Rccd1, Mmus\Sergef, Mmus\Als2, Mmus\Rcc1, Mmus\Rcbtb2, Mmus\Wbscr16, Mmus\Rpgr, Mmus\Gm15800, Mmus\Rcc2, Mmus\Herc1, Mmus\Nek9" "Hsap\RCC2, Hsap\NEK9, Hsap\RCBTB1, Hsap\RCBTB2, Hsap\ALS2, Hsap\HECTD4, Hsap\SERGEF, Hsap\RCC1L, Hsap\RCCD1, Hsap\HERC1, Hsap\RPGR, Hsap\RCC1, Hsap\HERC2" FBgn0015872 Drip Drip http://flybase.org/reports/FBgn0015872 FBgn0015156 protein_coding_gene water channel activity ; GO:0015250 | inferred from direct assay water channel activity ; GO:0015250 | inferred from sequence or structural similarity with UniProtKB:P55088 ion transmembrane transport ; GO:0034220 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 water homeostasis ; GO:0030104 | inferred from expression pattern water transport ; GO:0006833 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from direct assay regulation of oviposition ; GO:0046662 | inferred from mutant phenotype renal system process ; GO:0003014 | inferred from expression pattern integral component of membrane ; GO:0016021 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 "CG9023, DRIP, drip, I, anon-48Aa, Drip" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR022357:Major intrinsic protein, conserved site, IPR023271:Aquaporin-like" CG9023 11-Aug-17 DroID_v2017_08 "Drer\aqp8b, Drer\mipa, Drer\aqp8a.2, Drer\aqp7, Drer\aqp3a, Drer\aqp1a.1, Drer\aqp1a.2, Drer\si:dkey-30h22.11, Drer\aqp9b, Drer\mipb, Drer\aqp8a.1, Drer\aqp3b, Drer\aqp10a, Drer\aqp4" "Scer\YFL054C, Scer\AQY1, Scer\FPS1, Scer\YLL053C, Scer\AQY2" "Cele\aqp-7, Cele\aqp-4, Cele\aqp-5, Cele\aqp-3, Cele\aqp-6, Cele\aqp-2, Cele\aqp-8" "Xtro\LOC100489792, Xtro\fam188b, Xtro\aqp2, Xtro\aqp4, Xtro\aqp8, Xtro\aqp5, Xtro\mip, Xtro\LOC100216133" "Mmus\Mip, Mmus\Aqp2, Mmus\Aqp3, Mmus\Aqp9, Mmus\Aqp1, Mmus\Aqp4, Mmus\Aqp8, Mmus\Aqp7, Mmus\Aqp5, Mmus\Aqp6, Mmus\Fam188b" "Hsap\AQP9, Hsap\AQP7, Hsap\AQP1, Hsap\AQP10, Hsap\MIP, Hsap\FAM188B2, Hsap\AQP2, Hsap\AQP4, Hsap\AQP5, Hsap\AQP8, Hsap\AQP3, Hsap\AQP6" "viable,fertile" FBgn0260290 GSd442 - http://flybase.org/reports/FBgn0260290 gene - - - GSd442 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0250835 CG15394 - http://flybase.org/reports/FBgn0250835 protein_coding_gene - - - "CG15394, anon-SAGE:Wang-060" - CG15394 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060742 l(3)S066508 lethal (3) S066508 http://flybase.org/reports/FBgn0060742 gene - - - "0665/08, l(3)S066508" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267487 Ptp61F Protein tyrosine phosphatase 61F http://flybase.org/reports/FBgn0267487 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from mutant phenotype protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Abi negative regulation of insulin receptor signaling pathway ; GO:0046627 | inferred from genetic interaction with InR negative regulation of MAP kinase activity ; GO:0043407 | inferred from genetic interaction with rl negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D regulation of protein localization ; GO:0032880 | inferred from direct assay peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from direct assay negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from direct assay negative regulation of phosphatidylinositol 3-kinase signaling ; GO:0014067 | inferred from genetic interaction with Akt1 inferred from genetic interaction with Pi3K92E regulation of protein stability ; GO:0031647 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from physical interaction with dock negative regulation of peptidyl-tyrosine phosphorylation ; GO:0050732 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype germ-band extension ; GO:0007377 | inferred from direct assay peptidyl-tyrosine dephosphorylation ; GO:0035335 | inferred from direct assay regulation of epidermal growth factor-activated receptor activity ; GO:0007176 | inferred from genetic interaction with Egfr cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mitochondrial envelope ; GO:0005740 | inferred from direct assay "Ptp61F, PTP61F, PTP1B, CG9181, ptp61F, Ptp-61F, DPTP61F, R-PTP 61F, dPTP61F, dptp61F, CG9178, BEST:LP01280, anon-WO0118547.297, anon-WO0140519.98, DCPTP62A, CPtp62A" "IPR029021:Protein-tyrosine phosphatase-like, IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR003595:Protein-tyrosine phosphatase, catalytic" CG9181 11-Aug-17 DroID_v2017_08 "Drer\ptpn18, Drer\ptpn9a, Drer\ptpn9b, Drer\ptpn2b, Drer\ptpn5, Drer\ptpn22, Drer\ca16b, Drer\LOC101884960, Drer\ca16c, Drer\ptprz1b, Drer\ptprga, Drer\ptprr, Drer\ptpn2a, Drer\ptpn1" "Scer\PTP1, Scer\PTP2, Scer\PTP3" "Cele\F36H1.3, Cele\C55B7.3, Cele\H06I04.5, Cele\T22C1.8" "Xtro\ptprz1, Xtro\ptprr, Xtro\ptpn22, Xtro\ptpn9, Xtro\ptpn12, Xtro\ptpn23, Xtro\ptpn2, Xtro\LOC100489200, Xtro\ptpn1" "Mmus\Ptprr, Mmus\Ptpn7, Mmus\Ptpn9, Mmus\Ptpn5, Mmus\Ptpn12, Mmus\Ptpn20, Mmus\Ptpn1, Mmus\Ptprg, Mmus\Ptpn22, Mmus\Ptpn18, Mmus\Ptpn2, Mmus\Ptpn23" "Hsap\PTPN5, Hsap\PTPRR, Hsap\PTPN1, Hsap\PTPN18, Hsap\PTPN20, Hsap\PTPN2, Hsap\PTPN12, Hsap\PTPRG, Hsap\PTPN23, Hsap\PTPN7, Hsap\PTPN9, Hsap\PTPN22" " embryonic stage && pupal stage && adult stage , embryonic stage | stage 14 " embryonic central nervous system

DRSC08683 E 0.607831757 -0.262320692 0.414293953 -1.631065905 0.380960353 -0.511673265 FBgn0002631 E(spl)m5-HLH "Enhancer of split m5, helix-loop-helix" http://flybase.org/reports/FBgn0002631 - protein_coding_gene "protein homodimerization activity ; GO:0042803 | inferred from physical interaction with E(spl)m5-HLH protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with E(spl)m8-HLH sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650 compound eye development ; GO:0048749 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "CG6096, m5, E(spl)m5, E(spl) transcription unit m5, E(spl)M5, E(spl)-m5, HLH-m5, HLHm5, E(spl) m5, bHLHb36, E(spl)m5-HLH, E(spl)-M5, M5" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG6096 11-Aug-17 DroID_v2017_08 "Drer\her9, Drer\her11, Drer\her8.2, Drer\her3, Drer\her7, Drer\bhlhe40, Drer\hes2.1, Drer\her4.4, Drer\her1, Drer\her13, Drer\her5, Drer\her4.3, Drer\her15.1, Drer\her15.2, Drer\hes2.2, Drer\her4.2, Drer\bhlhe41, Drer\her6, Drer\LOC100149863, Drer\her8a, Drer\hes6, Drer\her12, Drer\her2" Scer\PHO4 "Cele\hlh-25, Cele\hlh-27, Cele\lin-22" "Xtro\hes2, Xtro\hes6.1" "Mmus\Bhlhe41, Mmus\Hes1, Mmus\Hes3, Mmus\Bhlhe40, Mmus\Hes2, Mmus\Hes5, Mmus\Hes7, Mmus\Hes6" "Hsap\BHLHE41, Hsap\HES3, Hsap\HES5, Hsap\HES6, Hsap\HES4, Hsap\BHLHE40, Hsap\HES2, Hsap\HES1, Hsap\HES7" " embryonic stage | stage 7-11 , embryonic stage | 2-6 hr , embryonic stage | stage 11-12 , embryonic stage | stage 11 , embryonic stage | stage 11-14 , embryonic stage | stage 10 , embryonic stage | stage 5 " " ectoderm

, mesoderm

, epidermis | restricted

, stomatogastric nervous system | primordium

, posterior midgut proper primordium

, vitellophage

, optic lobe | primordium

, supraesophageal ganglion

, organism | striped

" "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "macrochaeta,microchaeta,eo neuron,peripheral nervous system,central nervous system" FBgn0058062 CG40062 - http://flybase.org/reports/FBgn0058062 protein_coding_gene - - - CG40062 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265739 CR44546 - http://flybase.org/reports/FBgn0265739 non_protein_coding_gene - - - CR44546 - CR44546 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085587 CG41266 - http://flybase.org/reports/FBgn0085587 protein_coding_gene - - - CG41266 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004131 l(2)43Db lethal (2) 43Db http://flybase.org/reports/FBgn0004131 - gene - - - "43Db, l(2)43Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266590 CR45115 - http://flybase.org/reports/FBgn0266590 non_protein_coding_gene - - - CR45115 - CR45115 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034474 Obp56g Odorant-binding protein 56g http://flybase.org/reports/FBgn0034474 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "56g, CG13873, OBP56g, Obp56g, DmelObp56g" IPR006170:Pheromone/general odorant binding protein CG13873 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0060843 l(3)S049215 lethal (3) S049215 http://flybase.org/reports/FBgn0060843 gene - - - "0492/15, l(3)S049215" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0016909 l(3)X39 lethal (3) X39 http://flybase.org/reports/FBgn0016909 - gene - - - "X39, l(3)X39" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024320 Npc1a Niemann-Pick type C-1a http://flybase.org/reports/FBgn0024320 - protein_coding_gene lipid transporter activity ; GO:0005319 | inferred from electronic annotation with InterPro:IPR004765 "sperm individualization ; GO:0007291 | inferred from mutant phenotype sterol metabolic process ; GO:0016125 | inferred from mutant phenotype ecdysteroid biosynthetic process ; GO:0045456 | inferred from mutant phenotype molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype regulation of cholesterol transport ; GO:0032374 | inferred from direct assay" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000731, InterPro:IPR004765" "NPC1, dncp1a, Npc1, NPC1a, dNPC1a, Npc1_Dm, dNPC1, DmNPC, dmNPC1, dnpc1a, CG5722, npc1a, Npc1a, npc1" "IPR000731:Sterol-sensing domain, IPR003392:Protein patched/dispatched, IPR004765:Niemann-Pick C type protein, IPR032190:Niemann-Pick C1, N-terminal" CG5722 11-Aug-17 DroID_v2017_08 "Drer\npc1l1, Drer\npc1, Drer\scap" Scer\NCR1 "Cele\ncr-1, Cele\ncr-2" "Xtro\npc1l1, Xtro\npc1, Xtro\scap" "Mmus\Npc1l1, Mmus\Scap, Mmus\Npc1" "Hsap\NPC1, Hsap\SCAP, Hsap\NPC1L1" "neuroanatomy defective,aging defective,lethal,recessive,male sterile,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,eclosion defective,locomotor behavior defective,neurophysiology defective,viable,wild-type" "seminal vesicle,sperm individualization complex, with Npc1aUAS.TAvicGFP-EYFP, 2-286,individualization stage spermatid,rhabdomere | adult stage,adult brain,retina,eye,neuropil,sperm individualization complex, with Npc1aunspecified, 2-286" FBgn0014255 l(2)DB2 lethal (2) DB2 http://flybase.org/reports/FBgn0014255 - gene - - - "DB2, l(2)DB2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024697 dalm2 dalmatian-2 http://flybase.org/reports/FBgn0024697 - gene molecular_function ; GO:0003674 | no biological data available photoreceptor cell fate commitment ; GO:0046552 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "dalm, dalm2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "presumptive embryonic/larval peripheral nervous system,photoreceptor cell" FBgn0265931 CR44720 - http://flybase.org/reports/FBgn0265931 non_protein_coding_gene - - - CR44720 - CR44720 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265590 CR44417 - http://flybase.org/reports/FBgn0265590 non_protein_coding_gene - - - CR44417 - CR44417 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046331 l(2)38ABa lethal (2) 38ABa http://flybase.org/reports/FBgn0046331 gene - - - "lethal in 38A/B, l(2)38ABa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011150 l(1)Q226 lethal (1) Q226 http://flybase.org/reports/FBgn0011150 FBgn0010210 gene - - - l(1)Q226 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259619 B1517 - http://flybase.org/reports/FBgn0259619 gene - - - B1517 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029656 CG10793 - http://flybase.org/reports/FBgn0029656 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 microtubule-severing ATPase activity ; GO:0008568 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 CG10793 "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR006594:LIS1 homology motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10793 11-Aug-17 DroID_v2017_08 "Drer\katna1, Drer\katnal2" Scer\VPS4 - "Xtro\katnal2, Xtro\katna1" "Mmus\Katna1, Mmus\Katnal1, Mmus\Katnal2" "Hsap\KATNAL1, Hsap\KATNA1, Hsap\KATNAL2" viable FBgn0004100 l(2)60Cb lethal (2) 60Cb http://flybase.org/reports/FBgn0004100 - gene - - - l(2)60Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022326 l(1)A33.3 lethal (1) A33.3 http://flybase.org/reports/FBgn0022326 - gene - - - "A33.3, l(1)A33.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003893 tuh1 tumorous head on 1 http://flybase.org/reports/FBgn0003893 - gene - - - "tuh-1, tuh, tu-1, tuh1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,maternal effect,recessive,cold sensitive" "macrochaeta,maternal effect,cold sensitive" FBgn0259314 C891 - http://flybase.org/reports/FBgn0259314 gene - - - C891 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0035139 CG13891 - http://flybase.org/reports/FBgn0035139 protein_coding_gene - - - CG13891 - CG13891 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004051 Zerknittert Zerknittert http://flybase.org/reports/FBgn0004051 - gene - - - "Z, Zerknittert" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032721 CG10602 - http://flybase.org/reports/FBgn0032721 protein_coding_gene "leukotriene-A4 hydrolase activity ; GO:0004463 | inferred from electronic annotation with InterPro:IPR012777 structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR005822, InterPro:IPR023564 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 epoxide hydrolase activity ; GO:0004301 | inferred from biological aspect of ancestor with PANTHER:PTN000164255" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR005822, InterPro:IPR023564 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cellular lipid metabolic process ; GO:0044255 | inferred from biological aspect of ancestor with PANTHER:PTN000164255 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR005822, InterPro:IPR023564 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249" "pepCG10602, CG10602, mRpL13" "IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR012777:Leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR015211:Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal, IPR016024:Armadillo-type fold, IPR034015:Leukotriene A4 hydrolase-like, IPR005822:Ribosomal protein L13" CG10602 11-Aug-17 DroID_v2017_08 "Drer\rnpepl1, Drer\lta4h, Drer\rnpep, Drer\zgc:162939" Scer\LAP2 "Cele\ZC416.6, Cele\C42C1.11" "Xtro\rnpep, Xtro\c9orf3, Xtro\lta4h" "Mmus\2010111I01Rik, Mmus\Rnpepl1, Mmus\Rnpep, Mmus\Lta4h" "Hsap\LTA4H, Hsap\RNPEPL1, Hsap\RNPEP, Hsap\C9orf3" viable FBgn0259964 Sfp33A3 Seminal fluid protein 33A3 http://flybase.org/reports/FBgn0259964 protein_coding_gene enzyme inhibitor activity ; GO:0004857 | inferred from sequence model negative regulation of catalytic activity ; GO:0043086 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp33A3, CG42474" IPR002350:Kazal domain CG42474 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-195b11.3, Drer\si:dkey-203a12.2, Drer\si:dkey-77g12.1, Drer\si:dkey-203a12.8, Drer\zgc:158852" - - - "Mmus\Spink12, Mmus\Spink1, Mmus\Spink5, Mmus\Spink2" "Hsap\SPINK5, Hsap\SPINK2, Hsap\SPINK1" FBgn0005711 l(1)TK114 lethal (1) TK114 http://flybase.org/reports/FBgn0005711 - gene - - - "l114, l(1)TK114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0001699 l(1)ESHS20 lethal (1) ESHS20 http://flybase.org/reports/FBgn0001699 - gene - - - l(1)ESHS20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031301 CG14339 - http://flybase.org/reports/FBgn0031301 protein_coding_gene - - - CG14339 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG14339 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-254e1.1, Drer\cdc27" Scer\CDC27 Cele\mat-1 - Mmus\Cdc27 "Hsap\CDC27, Hsap\CFAP70" viable FBgn0259834 out outsiders http://flybase.org/reports/FBgn0259834 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 germ cell development ; GO:0007281 | inferred from mutant phenotype ectopic germ cell programmed cell death ; GO:0035234 | traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "out, CG8062, BcDNA:LD28120" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8062 11-Aug-17 DroID_v2017_08 "Drer\slc16a9b, Drer\slc16a9a, Drer\slc16a12b, Drer\slc16a12a, Drer\slc16a7, Drer\slc16a6b, Drer\si:ch211-234h8.7, Drer\slc16a6a, Drer\slc16a5a, Drer\slc16a5b, Drer\slc16a13, Drer\slc16a1a" "Scer\MCH4, Scer\MCH2, Scer\ESBP6, Scer\ATG22, Scer\MCH5" "Cele\slcf-1, Cele\mct-2" "Xtro\slc16a6, Xtro\slc16a9, Xtro\slc16a12, Xtro\slc16a7, Xtro\slc16a2, Xtro\slc16a3, Xtro\slc16a5" "Mmus\Slc16a4, Mmus\Slc16a11, Mmus\Slc16a9, Mmus\Slc16a12, Mmus\Slc16a5, Mmus\Slc16a13, Mmus\Slc16a14, Mmus\Slc16a6" "Hsap\SLC16A6, Hsap\SLC16A13, Hsap\SLC16A10, Hsap\SLC16A9, Hsap\SLC16A14, Hsap\SLC16A7, Hsap\SLC16A12, Hsap\SLC16A8, Hsap\SLC16A11, Hsap\SLC16A5, Hsap\SLC16A1, Hsap\SLC16A4, Hsap\SLC16A3" FBgn0260624 2L1738 - http://flybase.org/reports/FBgn0260624 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1738 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "dorsal air sac primordium,somatic clone" FBgn0038011 CG4066 - http://flybase.org/reports/FBgn0038011 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern mucus layer ; GO:0070701 | inferred from electronic annotation with InterPro:IPR028580 chorion ; GO:0042600 | inferred by curator from GO:0007304 CG4066 IPR028580:Mucin-2 CG4066 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260280 GSd435 - http://flybase.org/reports/FBgn0260280 gene - - - GSd435 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053680 CG33680 - http://flybase.org/reports/FBgn0053680 protein_coding_gene - - cellular_component ; GO:0005575 | no biological data available CG33680 IPR010562:Haemolymph juvenile hormone binding CG33680 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020333 anon-66Dd anon-66Dd http://flybase.org/reports/FBgn0020333 - gene - - - "547, anon-66Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262139 trh trachealess http://flybase.org/reports/FBgn0262139 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from physical interaction with tgo RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with sim inferred from sequence or structural similarity with HGNC:4910 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with tgo protein heterodimerization activity ; GO:0046982 | traceable author statement transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with tgo sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "open tracheal system development ; GO:0007424 | inferred from mutant phenotype limb development ; GO:0060173 | inferred from mutant phenotype epithelial cell fate determination, open tracheal system ; GO:0007425 | traceable author statement salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype epithelial tube formation ; GO:0072175 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype salivary gland development ; GO:0007431 | non-traceable author statement open tracheal system development ; GO:0007424 | traceable author statement epithelial cell fate determination, open tracheal system ; GO:0007425 | inferred from mutant phenotype salivary gland development ; GO:0007431 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with sim inferred from sequence or structural similarity with HGNC:4910 nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P05709 nucleus ; GO:0005634 | inferred from direct assay "trh, Trh, CG42865, trachealess, TRH, DMU42699, 3.1, l(3)10512, CG6883, bHLHe13, CG13885, BP1081, HDC07747" "IPR013655:PAS fold-3, IPR001610:PAC motif, IPR013767:PAS fold, IPR000014:PAS domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG42865 11-Aug-17 DroID_v2017_08 "Drer\hif1al2, Drer\hif1aa, Drer\hif1al, Drer\clockb, Drer\epas1b, Drer\sim1b, Drer\sim1a, Drer\hif1ab, Drer\npas1" - Cele\hlh-34 "Xtro\sim2, Xtro\npas3, Xtro\epas1, Xtro\hif1a" "Mmus\Epas1, Mmus\Hif3a, Mmus\Sim2, Mmus\Hif1a, Mmus\Npas3, Mmus\Npas1, Mmus\Sim1" "Hsap\SIM2, Hsap\NPAS2, Hsap\NPAS1, Hsap\SIM1, Hsap\NPAS3, Hsap\HIF1A, Hsap\HIF3A, Hsap\EPAS1" " embryonic stage , embryonic stage | stage >=8 , embryonic stage | stage >=13 , embryonic stage | stage >=11 " " embryonic/larval tracheal system

, embryonic/larval salivary gland

, central nervous system | restricted

, tracheal primordium

, tracheal pit

, salivary gland body primordium

, embryonic salivary gland

, filzkorper

, embryonic/larval trachea

, embryonic/larval salivary gland duct

" " embryonic stage |stage 14 , embryonic stage | stage 11 , embryonic stage | stage 15 , embryonic stage " " embryonic/larval posterior spiracle

, tracheal primordium

, embryonic/larval salivary gland duct

, embryonic/larval tracheal system

" "lethal,recessive,partially lethal - majority die,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible" "trachea,filzkorper,embryonic/larval salivary gland duct,embryonic/larval salivary gland,tracheal pit,tracheal branch primordium,abdominal lateral pentascolopidial chordotonal organ lch5 & growth cone,embryonic/larval trachea,embryonic/first instar larval cuticle,embryonic/larval muscle system,embryonic salivary gland duct,embryonic/larval tracheocyte,Malpighian tubule,ureter,embryonic/larval hindgut,tracheal primordium,presumptive embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/larval dorsal branch,ectopic,embryonic epidermis,chaeta,supernumerary" FBgn0083239 EP2444 EP2444 http://flybase.org/reports/FBgn0083239 gene - - - EP2444 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024684 l(1)HF326 lethal (1) HF326 http://flybase.org/reports/FBgn0024684 - gene - - - l(1)HF326 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020334 anon-66Dc anon-66Dc http://flybase.org/reports/FBgn0020334 - gene - - - "507, anon-66Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039809 CG15547 - http://flybase.org/reports/FBgn0039809 protein_coding_gene nucleoside diphosphate kinase activity ; GO:0004550 | inferred from electronic annotation with InterPro:IPR001564 molecular_function ; GO:0003674 | no biological data available CTP biosynthetic process ; GO:0006241 | inferred from electronic annotation with InterPro:IPR001564 UTP biosynthetic process ; GO:0006228 | inferred from electronic annotation with InterPro:IPR001564 GTP biosynthetic process ; GO:0006183 | inferred from electronic annotation with InterPro:IPR001564 nucleoside diphosphate phosphorylation ; GO:0006165 | inferred from electronic annotation with InterPro:IPR001564 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15547 IPR001564:Nucleoside diphosphate kinase CG15547 11-Aug-17 DroID_v2017_08 "Drer\nme4, Drer\nme8, Drer\nme6, Drer\nme7, Drer\nme2b.1, Drer\nme5" Scer\YNK1 Cele\R05G6.5 "Xtro\nme7, Xtro\nme9, Xtro\nme5, Xtro\nme3, Xtro\nme6, Xtro\nme2, Xtro\nme4" "Mmus\Nme1, Mmus\Nme8, Mmus\Nme2, Mmus\Nme9, Mmus\Nme3, Mmus\Nme5, Mmus\Nme4, Mmus\Nme7, Mmus\Nme6" "Hsap\NME4, Hsap\NME5, Hsap\NME3, Hsap\NME8, Hsap\NME2, Hsap\NME7, Hsap\NME6, Hsap\NME1, Hsap\NME9" viable FBgn0015385 en::Rnor\GR en::Rnor\GR http://flybase.org/reports/FBgn0015385 - engineered_fusion_gene - - - "en::GR, en::Rnor\GR" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015561 unpg unplugged http://flybase.org/reports/FBgn0015561 FBgn0014101 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype" "brain development ; GO:0007420 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement regulation of nervous system development ; GO:0051960 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Gbx, unp, upg, anon-45C, CG1650, unpg" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa, IPR031253:Homeobox protein unplugged" CG1650 11-Aug-17 DroID_v2017_08 "Drer\mnx2a, Drer\meox2b, Drer\hoxd3a, Drer\hoxb7a, Drer\hoxc8a, Drer\hoxb5a, Drer\gbx2, Drer\hoxa5a, Drer\meox2a, Drer\hoxb6a, Drer\hoxb1b, Drer\hoxb3a, Drer\hoxc6b, Drer\pdx1, Drer\hoxa1a, Drer\hoxa2b, Drer\hoxb4a, Drer\hoxc6a, Drer\hoxa3a, Drer\hoxb5b, Drer\hoxc4a, Drer\hoxb6b, Drer\hoxc3a, Drer\hoxa4a, Drer\evx1, Drer\hoxb2a, Drer\hoxa10b, Drer\hoxd10a, Drer\hoxc1a, Drer\meox1, Drer\gsx2, Drer\hoxb8b, Drer\hoxc5a, Drer\hoxa9b, Drer\gsx1, Drer\mnx1, Drer\hoxd4a, Drer\gbx1, Drer\hoxb1a" - "Cele\ceh-62, Cele\ceh-12, Cele\mls-2, Cele\ceh-63" "Xtro\hoxa1, Xtro\gbx2.2, Xtro\hoxd1, Xtro\hoxc10, Xtro\hoxb1, Xtro\hoxb8, Xtro\gbx2.1, Xtro\meox2, Xtro\hoxc5, Xtro\hoxb4, Xtro\hoxb7, Xtro\hoxa2, Xtro\hoxd8, Xtro\hoxa5, Xtro\pdx1, Xtro\hoxb5, Xtro\mnx1, Xtro\hoxd3, Xtro\hoxd10, Xtro\hoxa3, Xtro\hoxb2, Xtro\hoxc8, Xtro\hoxb3, Xtro\hoxb6, Xtro\hoxc3, Xtro\gsx1, Xtro\hoxc4, Xtro\gsx2" "Mmus\Hoxc8, Mmus\Hoxa2, Mmus\Hoxc10, Mmus\Hoxa3, Mmus\Gsx1, Mmus\Hoxa1, Mmus\Gsx2, Mmus\Gbx1, Mmus\Hoxd10, Mmus\Hoxa4, Mmus\Pdx1, Mmus\Mnx1, Mmus\Hoxb3, Mmus\Hoxb2, Mmus\Meox1, Mmus\Hoxd1, Mmus\Hoxa10, Mmus\Hoxb1, Mmus\Hoxb4, Mmus\Hoxb8, Mmus\Hoxa5, Mmus\Hoxb7, Mmus\Hoxa6, Mmus\Hoxd8, Mmus\Hoxa7, Mmus\Hoxb5, Mmus\Gbx2, Mmus\Hoxc6, Mmus\Hoxb6, Mmus\Hoxd3, Mmus\Hoxd4, Mmus\Hoxc5, Mmus\Hoxc4, Mmus\Meox2" "Hsap\HOXB1, Hsap\HOXA7, Hsap\HOXA2, Hsap\GBX2, Hsap\HOXA3, Hsap\HOXB6, Hsap\PDX1, Hsap\GSX1, Hsap\HOXB3, Hsap\HOXB8, Hsap\HOXB7, Hsap\GSX2, Hsap\GBX1, Hsap\HOXB4, Hsap\HOXD3, Hsap\MEOX1, Hsap\HOXC8, Hsap\HOXD1, Hsap\HOXB2, Hsap\HOXC5, Hsap\HOXA1, Hsap\HOXC10, Hsap\HOXA4, Hsap\HOXC6, Hsap\HOXA10, Hsap\HOXB5, Hsap\MEOX2, Hsap\HOXC4, Hsap\HOXD10, Hsap\HOXD4, Hsap\MNX1, Hsap\HOXA5, Hsap\HOXA6, Hsap\HOXD8" " embryonic stage | stage 13 , embryonic stage | stage 11 , embryonic stage | stage 8 , embryonic stage | stage 9 , embryonic stage | stage 14 , embryonic stage " " metathoracic tracheal pit

, mesothoracic tracheal pit

, ventral midline

, neuroblast

, ectoderm | lateral prothoracic segment

, embryonic/larval ganglionic branch

, abdominal tracheal pit 1--7

, central nervous system

, ectoderm | lateral labial segment

, cerebral branch

, tracheal system

" " embryonic stage | stage 13 , embryonic stage | stage 11 , embryonic stage | stage 9 , embryonic stage | stage 14 , embryonic stage | stage 8 , embryonic stage " " mesothoracic tracheal pit

, cerebral branch | precursor

, ectoderm | lateral prothoracic segment

, embryonic/larval ganglionic branch

, abdominal tracheal pit 1--7

, ventral midline

, metathoracic tracheal pit

, neuroblast

, central nervous system

, ectoderm | lateral labial segment

, tracheal system

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "cerebral branch,cerebral anastomosis,ganglionic branch 0,ganglionic branch 1,ganglionic branch 2,ganglionic branch 3,ganglionic branch 4,ganglionic branch 5,ganglionic branch 6,ganglionic branch 7,ganglionic branch 8,ganglionic branch 9,wing,trichogen cell,mesothoracic tergum" FBgn0037926 Elp1 Elongator complex protein 1 http://flybase.org/reports/FBgn0037926 protein_coding_gene phosphorylase kinase regulator activity ; GO:0008607 | inferred from sequence or structural similarity with UniProtKB:O95163 "tRNA wobble uridine modification ; GO:0002098 | inferred from electronic annotation with InterPro:IPR006849 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:O95163 RNA interference ; GO:0016246 | inferred from mutant phenotype dosage compensation by hyperactivation of X chromosome ; GO:0009047 | inferred from genetic interaction with roX2, roX1" Elongator holoenzyme complex ; GO:0033588 | inferred from electronic annotation with InterPro:IPR006849 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:O95163 transcription elongation factor complex ; GO:0008023 | inferred from sequence or structural similarity with UniProtKB:O95163 "elp1, D-elp1, Elp1, CG10535, ELP1" "IPR006849:Elongator complex subunit Iki3, IPR015943:WD40/YVTN repeat-like-containing domain" CG10535 11-Aug-17 DroID_v2017_08 Drer\ikbkap Scer\IKI3 Cele\elpc-1 Xtro\ikbkap Mmus\Ikbkap Hsap\IKBKAP "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0031139 CG11227 - http://flybase.org/reports/FBgn0031139 protein_coding_gene - - - CG11227 IPR031732:Protein of unknown function DUF4729 CG11227 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033405 CG13954 - http://flybase.org/reports/FBgn0033405 protein_coding_gene - - - CG13954 - CG13954 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053869 His4:CG33869 His4:CG33869 http://flybase.org/reports/FBgn0053869 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33869, His4:CG33869" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33869 11-Aug-17 DroID_v2017_08 "Drer\LOC570405, Drer\si:ch211-113a14.26, Drer\LOC562770, Drer\si:dkey-261m9.18, Drer\hist1h4l, Drer\zgc:165555, Drer\si:dkey-23a13.7, Drer\zgc:153409, Drer\LOC100150038, Drer\si:dkey-108k21.12, Drer\LOC100331412, Drer\si:dkey-108k21.28, Drer\zgc:194989, Drer\si:ch73-36p18.4, Drer\LOC794549, Drer\si:dkey-261m9.17, Drer\zgc:154164, Drer\si:ch211-113a14.6, Drer\si:ch73-36p18.3, Drer\si:dkey-108k21.19, Drer\LOC100329358, Drer\si:ch73-368j24.14, Drer\zgc:163040, Drer\si:ch211-113a14.17" "Scer\HHF1, Scer\HHF2" "Cele\his-26, Cele\his-18, Cele\his-50, Cele\his-5, Cele\his-60, Cele\his-28, Cele\his-67, Cele\his-1, Cele\his-31, Cele\his-37, Cele\his-64, Cele\his-46, Cele\his-38, Cele\his-10, Cele\his-14, Cele\his-56" "Xtro\hist1h4c, Xtro\LOC100485271, Xtro\hist1h4k, Xtro\hist1h4a, Xtro\LOC101732103, Xtro\LOC100493041" "Mmus\Hist1h4a, Mmus\Hist1h4h, Mmus\Hist4h4, Mmus\Hist1h4d, Mmus\Hist1h4f, Mmus\Hist1h4k, Mmus\Hist1h4i, Mmus\Hist1h4b, Mmus\Hist1h4m, Mmus\Hist1h4j, Mmus\Hist1h4n, Mmus\Hist2h4, Mmus\Hist1h4c" "Hsap\HIST4H4, Hsap\HIST2H4A, Hsap\HIST2H4B, Hsap\HIST1H4E, Hsap\HIST1H4G, Hsap\HIST1H4A, Hsap\HIST1H4L, Hsap\HIST1H4D, Hsap\HIST1H4F, Hsap\HIST1H4C, Hsap\HIST1H4H, Hsap\HIST1H4B, Hsap\HIST1H4I, Hsap\HIST1H4K, Hsap\HIST1H4J" FBgn0259745 wech wech http://flybase.org/reports/FBgn0259745 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315 protein binding, bridging ; GO:0030674 | inferred from physical interaction with Ilk, rhea" instar larval development ; GO:0002168 | inferred from mutant phenotype regulation of cell-cell adhesion mediated by integrin ; GO:0033632 | inferred from physical interaction with rhea muscle attachment ; GO:0016203 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR000315 muscle tendon junction ; GO:0005927 | inferred from direct assay "Wech, CG1624, dpld, lin-41, wech, CG42396, Dpld" "IPR011042:Six-bladed beta-propeller, TolB-like, IPR000315:B-box-type zinc finger, IPR013017:NHL repeat, subgroup, IPR001258:NHL repeat" CG42396 11-Aug-17 DroID_v2017_08 Drer\trim71 - "Cele\lin-41, Cele\nhl-1" Xtro\trim71 "Mmus\Trim3, Mmus\Trim42, Mmus\Trim71" "Hsap\TRIM71, Hsap\TRIM42, Hsap\TRIM3" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,viable" "embryonic/larval somatic muscle,eye,ommatidium,interommatidial bristle,pigment cell,lens" FBgn0265508 CR44370 - http://flybase.org/reports/FBgn0265508 non_protein_coding_gene - - - CR44370 - CR44370 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010269 Dsor1 Downstream of raf1 http://flybase.org/reports/FBgn0010269 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 MAP kinase kinase activity ; GO:0004708 | inferred from sequence or structural similarity MAP kinase kinase activity ; GO:0004708 | traceable author statement receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement" "positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D mitotic DNA replication checkpoint ; GO:0033314 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from genetic interaction with Raf cellular response to X-ray ; GO:0071481 | inferred from mutant phenotype MAPK cascade ; GO:0000165 | non-traceable author statement mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from genetic interaction with sl protein phosphorylation ; GO:0006468 | non-traceable author statement signal transduction ; GO:0007165 | inferred from mutant phenotype hemocyte differentiation ; GO:0042386 | inferred from genetic interaction with hop anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement protein phosphorylation ; GO:0006468 | traceable author statement" condensed chromosome ; GO:0000793 | inferred from direct assay nuclear envelope ; GO:0005635 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 "Dsor, DSor1, MEK, MEK1/2, DSORT, sor/MEK1, DRODSOR1, SOR, CG15793, mek, EK1-1, sor, MAPKK, Mek, D-SOR, DSOR1, D-sor, D-MEK/Dsor, Su(Raf)34B, Dmek, DSor, D-MEK, dsor1, D-Mek, D-mek, D-sor-1, DMEK-1, Dsor1, Sor, dSor, dMEK, MEK/Dsor1, D-Sor, dSor1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG15793 11-Aug-17 DroID_v2017_08 "Drer\map2k2b, Drer\map2k6, Drer\map2k2a, Drer\map2k5, Drer\map2k1, Drer\nek1, Drer\map2k4a" "Scer\MKK1, Scer\PBS2, Scer\STE7, Scer\MKK2" "Cele\mek-2, Cele\sek-1, Cele\mkk-4" "Xtro\map2k6, Xtro\map2k5, Xtro\map2k1" "Mmus\Map2k5, Mmus\Map2k4, Mmus\Map2k1, Mmus\Map2k6, Mmus\Map2k2" "Hsap\MAP2K6, Hsap\MAP2K1, Hsap\MAP2K5, Hsap\MAP2K2, Hsap\MAP2K4" embryonic stage -- adult stage "lethal,recessive,wild-type,polyphasic,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,dominant,some die during immature adult stage,lethal - all die before end of pupal stage,some die during pupal stage" "ommatidium,germarium,spectrosome | supernumeraryunspecified,imaginal disc,somatic clone,dorsal appendage,photoreceptor cell R7,egg chamber,maternal effect,chorion | maternal effect | somatic clone,eye,pigment cell,embryonic dorsal epidermis,intermediate ventral neurectoderm,eye photoreceptor cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,wing vein,male germline cell,cyst progenitor cell,germline stem cell,mesothoracic tergum,adult heart,adult heart muscle" DRSC18462 IEK -1.737304305 -1.207622298 -2.015873569 -1.892313732 -5.420191583 -5.003384291 FBgn0084044 CG41484 - http://flybase.org/reports/FBgn0084044 protein_coding_gene - - - CG41484 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250757 CG42235 - http://flybase.org/reports/FBgn0250757 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734 "CG8951, CG14539, CG8957, CG8934, CG8932, CG31090, CG42235, CG8966, dSLC5A10" IPR001734:Sodium/solute symporter CG42235 11-Aug-17 DroID_v2017_08 "Drer\slc5a8, Drer\LOC101882918, Drer\slc5a3a, Drer\slc5a2, Drer\slc5a9, Drer\LOC568338, Drer\slc5a8l, Drer\slc5a6b, Drer\slc5a5, Drer\slc5a1, Drer\slc5a11, Drer\slc5a6a, Drer\slc5a12, Drer\si:dkeyp-9d4.5" Scer\DUR3 "Cele\ZK822.5, Cele\F52H2.4" "Xtro\slc5a2, Xtro\slc5a12, Xtro\slc5a1.1, Xtro\slc5a8, Xtro\slc5a9, Xtro\slc5a11, Xtro\slc5a5" "Mmus\Slc5a12, Mmus\Slc5a9, Mmus\Slc5a5, Mmus\Slc5a4a, Mmus\Slc5a1, Mmus\Slc5a11, Mmus\Gm5134, Mmus\Slc5a2, Mmus\Slc5a4b, Mmus\Slc5a6, Mmus\Slc5a3, Mmus\Slc5a10, Mmus\Slc5a8" "Hsap\SLC5A12, Hsap\SLC5A2, Hsap\SLC5A1, Hsap\SLC5A9, Hsap\SLC5A5, Hsap\SLC5A11, Hsap\SLC5A10, Hsap\SLC5A3, Hsap\SLC5A6, Hsap\SLC5A4, Hsap\SLC5A8" FBgn0038787 CG4360 - http://flybase.org/reports/FBgn0038787 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG4360 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4360 11-Aug-17 DroID_v2017_08 "Drer\zgc:171901, Drer\im:7142702, Drer\bcl11aa, Drer\znf296, Drer\znf319, Drer\bcl11ab, Drer\znf1004" Scer\COM2 "Cele\klu-1, Cele\Y55F3AM.14, Cele\C27A12.2, Cele\Y111B2A.10, Cele\sma-9, Cele\klf-1, Cele\pat-9" "Xtro\bcl11a, Xtro\sall4, Xtro\bcl11b" "Mmus\Gm14124, Mmus\Bcl11b, Mmus\Zkscan5, Mmus\Zfp184, Mmus\Bcl11a, Mmus\Zfp553, Mmus\Zfp39" "Hsap\BCL11A, Hsap\RBAK-RBAKDN, Hsap\ZNF296, Hsap\ZNF551, Hsap\ZNF626, Hsap\ZNF197, Hsap\ZKSCAN5, Hsap\ZNF48" viable FBgn0040399 E(spl)m8-HLH::E(spl)mdelta-HLH - http://flybase.org/reports/FBgn0040399 engineered_fusion_gene - - - "E(spl)m8-HLH::E(spl)mdelta-HLH, E(spl)::E(spl)mdelta-HLH, E(spl)::HLHmdelta" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033628 CG13203 - http://flybase.org/reports/FBgn0033628 protein_coding_gene - - - "anon-EST:Posey175, CG13203" - CG13203 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060398 l(3)S132209b lethal (3) S132209b http://flybase.org/reports/FBgn0060398 gene - - - "1322/09, l(3)S132209b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027243 l(1)G0268 lethal (1) G0268 http://flybase.org/reports/FBgn0027243 - gene - - - l(1)G0268 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" pupa FBgn0085218 CG34189 - http://flybase.org/reports/FBgn0085218 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with HGNC:12726 protein homooligomerization ; GO:0051260 | inferred from sequence or structural similarity with HGNC:12726 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:12726 CG34189 "IPR002919:Trypsin Inhibitor-like, cysteine rich domain" CG34189 11-Aug-17 DroID_v2017_08 - - "Cele\C25E10.8, Cele\spi-1, Cele\F53C11.9, Cele\B0238.12, Cele\Y26D4A.12, Cele\C53B7.2, Cele\K07A1.6, Cele\swm-1, Cele\F32D8.3, Cele\F36H9.4, Cele\C10G8.4, Cele\C25E10.10, Cele\C25E10.7, Cele\T01D3.3" - - - FBgn0051736 CG31736 - http://flybase.org/reports/FBgn0051736 protein_coding_gene - - - CG31736 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053971 Ir62a Ionotropic receptor 62a http://flybase.org/reports/FBgn0053971 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG12090, IR62a, DmelIR62a, CG33971, Ir62a" - CG33971 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267779 CR46110 - http://flybase.org/reports/FBgn0267779 non_protein_coding_gene - - - CR46110 - CR46110 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038702 CG3739 - http://flybase.org/reports/FBgn0038702 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR008758 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008758 - CG3739 "IPR008758:Peptidase S28, IPR029058:Alpha/Beta hydrolase fold" CG3739 11-Aug-17 DroID_v2017_08 "Drer\prss16, Drer\prss16" - "Cele\F28E10.5, Cele\pcp-3, Cele\pcp-2, Cele\K12H4.7, Cele\pcp-4, Cele\C26B9.5, Cele\pcp-1, Cele\F19C7.4, Cele\F56F10.1, Cele\F19C7.2" "Xtro\prss16, Xtro\LOC100145763" Mmus\Prss16 Hsap\PRSS16 "viable,visible" trichogen cell FBgn0267144 CR45584 - http://flybase.org/reports/FBgn0267144 non_protein_coding_gene - - - CR45584 - CR45584 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031725 DIP-eta Dpr-interacting protein eta http://flybase.org/reports/FBgn0031725 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CT33567, CG14010, 14010, DIP-eta" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG14010 11-Aug-17 DroID_v2017_08 "Drer\f11r.1, Drer\vsig8a, Drer\si:ch211-215e19.3, Drer\negr1, Drer\kirrel3l, Drer\si:ch211-9d9.7, Drer\igsf9a, Drer\si:ch1073-459j12.1, Drer\esamb, Drer\itgb4, Drer\si:dkey-250k15.10, Drer\kirrela, Drer\lrit1a, Drer\zgc:110372, Drer\si:ch211-261c8.5, Drer\jam2b, Drer\LOC100151468, Drer\f11r.2, Drer\kirrel3a, Drer\sdk1b, Drer\si:zfos-1011f11.1, Drer\lrit1b, Drer\cxadr, Drer\zgc:153073, Drer\igsf11, Drer\ntm, Drer\ncam1b, Drer\LOC565947, Drer\kirrelb, Drer\sdk1a, Drer\jam3a, Drer\dscama, Drer\pigrl4.2, Drer\kirrel3b, Drer\gpa33, Drer\lrit3b, Drer\jam2a, Drer\mxra8b, Drer\si:dkey-65b12.12, Drer\lrit3a, Drer\cxcr3.1, Drer\lsamp, Drer\jam3b, Drer\vsig8b, Drer\nptnb, Drer\opcml, Drer\mxra8a, Drer\paplna, Drer\esama, Drer\igsf9bb, Drer\ush2a" - "Cele\sma-10, Cele\rig-5" "Xtro\negr1, Xtro\ntm, Xtro\nptn, Xtro\kirrel2, Xtro\lsamp, Xtro\igsf9b, Xtro\papln, Xtro\bsg, Xtro\lrit3" "Mmus\Vsir, Mmus\Emb, Mmus\Vsig1, Mmus\Igsf9b, Mmus\Clmp, Mmus\Mxra8, Mmus\Negr1, Mmus\Gpa33, Mmus\Gm1123, Mmus\Cxadr, Mmus\F11r, Mmus\Hepacam2, Mmus\Ntm, Mmus\Nptn, Mmus\Kirrel2, Mmus\Igsf11, Mmus\Ptprq, Mmus\Jam2, Mmus\Opcml, Mmus\Vsig8, Mmus\Papln, Mmus\Kirrel, Mmus\Iglon5, Mmus\Lsamp, Mmus\Kirrel3, Mmus\Sdk1, Mmus\Jam3, Mmus\Esam, Mmus\Lrit3, Mmus\Vsig2, Mmus\Lrit1, Mmus\Bsg, Mmus\Igsf5" "Hsap\LRIT3, Hsap\LRIT1, Hsap\C1orf204, Hsap\NTM, Hsap\SDK1, Hsap\JAM2, Hsap\KIRREL3, Hsap\C10orf54, Hsap\LSAMP, Hsap\USH2A, Hsap\CXADR, Hsap\IGSF5, Hsap\ESAM, Hsap\IGSF11, Hsap\KIRREL, Hsap\JAM3, Hsap\OPCML, Hsap\BSG, Hsap\GPA33, Hsap\VSIG8, Hsap\IGLON5, Hsap\F11R, Hsap\KIRREL2, Hsap\MXRA8, Hsap\VSIG2, Hsap\CLMP, Hsap\NPTN, Hsap\IGSF9B, Hsap\EMB, Hsap\PAPLN, Hsap\VSIG1, Hsap\NEGR1" FBgn0266236 CR44931 - http://flybase.org/reports/FBgn0266236 non_protein_coding_gene - - - "CR44931, lincRNA.699" - CR44931 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030010 CG10959 - http://flybase.org/reports/FBgn0030010 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG10959 "IPR013087:Zinc finger C2H2-type, IPR022755:Zinc finger, double-stranded RNA binding" CG10959 11-Aug-17 DroID_v2017_08 "Drer\zbtb18, Drer\si:dkey-253d23.8, Drer\zbtb24, Drer\hic1l, Drer\zbtb7a, Drer\patz1, Drer\mynn, Drer\si:dkey-253d23.11, Drer\zbtb48, Drer\zbtb16b, Drer\zbtb8b, Drer\bcl6ab, Drer\si:dkey-7l6.3, Drer\zbtb16a, Drer\zbtb20, Drer\hic1, Drer\zgc:165515, Drer\hic2" "Scer\YPR015C, Scer\CMR3, Scer\AZF1" "Cele\M03D4.4, Cele\T20H4.2, Cele\blmp-1, Cele\eor-1, Cele\hinf-1, Cele\Y55F3AM.14" "Xtro\zbtb43, Xtro\hic1, Xtro\gzf1, Xtro\znf238.2, Xtro\zbtb41, Xtro\zbtb11, Xtro\hic2, Xtro\mtf1, Xtro\bcl6, Xtro\zbtb14" "Mmus\Zbtb43, Mmus\Zbtb7c, Mmus\Zbtb16, Mmus\Zfp62, Mmus\Bcl6, Mmus\Zbtb49, Mmus\Mtf1, Mmus\Zfp651, Mmus\Zfp653, Mmus\Zbtb17, Mmus\Hic2, Mmus\Zbtb20, Mmus\Zbtb7a, Mmus\Zbtb38, Mmus\Hic1, Mmus\Gzf1, Mmus\Zbtb18" "Hsap\ZBTB7C, Hsap\ZNF653, Hsap\ZBTB38, Hsap\ZBTB17, Hsap\ZSCAN10, Hsap\HIC2, Hsap\MTF1, Hsap\ZBTB16, Hsap\HIC1, Hsap\BCL6, Hsap\ZBTB48, Hsap\ZBTB11, Hsap\ZBTB7A, Hsap\ZNF589, Hsap\ZNF441, Hsap\ZBTB20, Hsap\ZBTB18" "viable,fertile" DRSC17769 E -0.413203017 -0.103136761 1.779604587 0.18891419 0.115442834 0.045705065 FBgn0063927 GS2159 GS2159 http://flybase.org/reports/FBgn0063927 gene - - - GS2159 - - 11-Aug-17 DroID_v2017_08 - - - - - - long lived FBgn0065858 l(2)SH0287 lethal (2) SH0287 http://flybase.org/reports/FBgn0065858 gene - - - "l(2)SH0287, l(2)SH2 0287" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050249 tRNA:His-GTG-1-1 transfer RNA:Histidine-GTG 1-1 http://flybase.org/reports/FBgn0050249 tRNA_gene CAC codon-amino acid adaptor activity ; GO:0033426 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033426 cytosol ; GO:0005829 | inferred by curator from GO:0033426 "AE002787.trna21-HisGTG, tRNA:H:GTG:AE002787-d, CR30249, tRNA[His], chr2R.trna80-HisGTG, tRNA-His-GTG-1-1, tRNA:His-GTG-1-1, tRNA:CR30249, CAC" - CR30249 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027090 GlnRS Glutaminyl-tRNA synthetase http://flybase.org/reports/FBgn0027090 "FBgn0010867, FBgn0027545" protein_coding_gene "glutamine-tRNA ligase activity ; GO:0004819 | inferred from electronic annotation with InterPro:IPR004514, InterPro:IPR007638 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000924, InterPro:IPR001412, InterPro:IPR004514, InterPro:IPR007638, InterPro:IPR007639, InterPro:IPR020058, InterPro:IPR020059, InterPro:IPR020061 glutamine-tRNA ligase activity ; GO:0004819 | traceable author statement glutamine-tRNA ligase activity ; GO:0004819 | inferred from sequence or structural similarity" "glutaminyl-tRNA aminoacylation ; GO:0006425 | inferred from electronic annotation with InterPro:IPR004514, InterPro:IPR007638 glutaminyl-tRNA aminoacylation ; GO:0006425 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000924, InterPro:IPR004514, InterPro:IPR007638, InterPro:IPR007639, InterPro:IPR020059, InterPro:IPR020061 cytoplasm ; GO:0005737 | traceable author statement aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay" "Aast-g1n, GlnRS, QRS, l(3)05461, CG10506, BcDNA:GH11673, qars, Aats-gln" "IPR000924:Glutamyl/glutaminyl-tRNA synthetase, IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR004514:Glutamine-tRNA synthetase, IPR007638:Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2, IPR007639:Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, IPR011035:Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR020056:Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain, IPR020058:Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain, IPR020059:Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain, IPR020061:Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain" CG10506 11-Aug-17 DroID_v2017_08 Drer\qars "Scer\GUS1, Scer\GLN4" Cele\qars-1 Xtro\qars Mmus\Qars Hsap\QARS embryonic stage

ubiquitous "lethal,recessive,neuroanatomy defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "adult antennal lobe projection neuron,somatic clone" FBgn0051827 CG31827 - http://flybase.org/reports/FBgn0051827 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - CG31827 "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG31827 11-Aug-17 DroID_v2017_08 - - Cele\try-1 - "Mmus\Klk1b26, Mmus\Klk1b5, Mmus\Klk1, Mmus\Klk1b11, Mmus\Klk1b24, Mmus\F9, Mmus\Klk1b8, Mmus\Klk11, Mmus\Klk1b22, Mmus\Egfbp2, Mmus\Klk1b9, Mmus\Klk1b27, Mmus\Klkb1, Mmus\Klk1b21, Mmus\Klk1b4, Mmus\Klk1b3, Mmus\Klk1b16, Mmus\F11, Mmus\Klk1b1" "Hsap\F10, Hsap\F11, Hsap\KLK1, Hsap\KLK11, Hsap\KLK3, Hsap\F9, Hsap\KLKB1, Hsap\KLK2" FBgn0025145 ms(3)A2 ms(3)A2 http://flybase.org/reports/FBgn0025145 - gene - - - ms(3)A2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0060963 l(3)S032111b lethal (3) S032111b http://flybase.org/reports/FBgn0060963 gene - - - "0321/11, l(3)S032111b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0037755 CG12945 - http://flybase.org/reports/FBgn0037755 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available endomembrane system ; GO:0012505 | inferred from direct assay CG12945 - CG12945 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030217 CG2124 - http://flybase.org/reports/FBgn0030217 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:25790 biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:25790 CG2124 IPR013584:RAP domain CG2124 11-Aug-17 DroID_v2017_08 "Drer\fastkd5, Drer\fastk, Drer\fastkd3" - - "Xtro\fastkd5, Xtro\tbrg4" "Mmus\Fastkd5, Mmus\Fastkd3" "Hsap\FASTKD3, Hsap\TBRG4, Hsap\FASTKD5, Hsap\FASTKD2, Hsap\FASTKD1" viable DRSC18208 K 0.641232138 -0.037572463 -0.295342998 0.371541342 0.193924177 2.055819098 FBgn0033775 Cyp9h1 Cyp9h1 http://flybase.org/reports/FBgn0033775 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "9h1, CG17577, Cyp9h1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG17577 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp4v8, Drer\cyp3c4, Drer\cyp4v7, Drer\cyp3c2, Drer\cyp3c3, Drer\tbxas1, Drer\cyp4t8, Drer\cyp3c1, Drer\cyp4f3" Scer\ERG11 "Cele\cyp-13A10, Cele\cyp-13B2, Cele\cyp-25A2, Cele\cyp-13A2, Cele\cyp-31A3, Cele\cyp-43A1, Cele\cyp-25A4, Cele\cyp-29A4, Cele\cyp-25A6, Cele\cyp-13A4, Cele\cyp-13A11, Cele\cyp-31A2, Cele\cyp-42A1, Cele\cyp-13A12, Cele\cyp-32A1, Cele\cyp-13B1, Cele\cyp-44A1, Cele\cyp-29A3, Cele\cyp-13A5, Cele\cyp-25A3, Cele\cyp-25A1, Cele\cyp-13A6, Cele\cyp-29A2, Cele\cyp-37B1, Cele\cyp-13A1, Cele\cyp-13A3, Cele\cyp-13A8, Cele\cyp-32B1, Cele\cyp-13A7" "Xtro\cyp3a5, Xtro\tbxas1, Xtro\cyp3a4, Xtro\LOC100494419" "Mmus\Cyp4b1, Mmus\Tbxas1, Mmus\Cyp3a41a, Mmus\Cyp3a41b, Mmus\Cyp3a16, Mmus\Cyp4f15, Mmus\Cyp3a44, Mmus\Cyp3a59, Mmus\Cyp4a14, Mmus\Cyp3a57, Mmus\Cyp3a25, Mmus\Cyp4f39, Mmus\Cyp4f16, Mmus\Cyp4f13, Mmus\Cyp4a12b, Mmus\Cyp4v3, Mmus\Cyp4a12a, Mmus\Cyp3a13, Mmus\Cyp4a10, Mmus\Cyp4f18, Mmus\Cyp4a32, Mmus\Cyp3a11, Mmus\Cyp4f37, Mmus\Cyp4f14, Mmus\Cyp4a31" "Hsap\CYP3A7, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4F3, Hsap\CYP3A4, Hsap\CYP4A22, Hsap\CYP4X1, Hsap\CYP4F2, Hsap\CYP4Z1, Hsap\TBXAS1, Hsap\CYP3A43, Hsap\CYP4F11, Hsap\CYP4V2, Hsap\CYP4B1, Hsap\CYP4F12, Hsap\CYP3A5, Hsap\CYP4A11, Hsap\CYP4F8, Hsap\CYP4F22" viable FBgn0005271 l(3)SG91 lethal (3) SG91 http://flybase.org/reports/FBgn0005271 - gene - - - l(3)SG91 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,heat sensitive,some die during larval stage" FBgn0015825 T-B9.4 T-B9.4 http://flybase.org/reports/FBgn0015825 - gene - - - T-B9.4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025757 l(3)93DFe lethal (3) 93DFe http://flybase.org/reports/FBgn0025757 - gene - - - l(3)93DFe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260490 l(3)8172 - http://flybase.org/reports/FBgn0260490 gene - axonogenesis ; GO:0007409 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - l(3)8172 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,axon,dendrite" FBgn0017581 Lk6 Lk6 kinase http://flybase.org/reports/FBgn0017581 "FBgn0037945, FBgn0037946, FBgn0046349" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 calcium-dependent protein serine/threonine kinase activity ; GO:0009931 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 calmodulin binding ; GO:0005516 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 protein kinase activity ; GO:0004672 | inferred from direct assay calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay kinase activity ; GO:0016301 | inferred from mutant phenotype protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement mitogen-activated protein kinase binding ; GO:0051019 | inferred from physical interaction with rl" protein phosphorylation ; GO:0006468 | non-traceable author statement sleep ; GO:0030431 | inferred from expression pattern positive regulation of peptidyl-serine phosphorylation ; GO:0033138 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr protein autophosphorylation ; GO:0046777 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 microtubule-based process ; GO:0007017 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay regulation of growth ; GO:0040008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "Lk6, CG17342, LK6, lk6, MNK/LK6, MESR8, CG6929, anon-WO0172774.84" "IPR017441:Protein kinase, ATP binding site, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG17342 11-Aug-17 DroID_v2017_08 "Drer\mknk2a, Drer\mknk2b, Drer\mknk1" "Scer\RCK2, Scer\RCK1" "Cele\ZC373.4, Cele\mnk-1" "Xtro\mknk1, Xtro\mknk2" "Mmus\Mknk2, Mmus\Mknk1" "Hsap\MKNK2, Hsap\MKNK1" "small body,decreased cell number,lethal,viable,fertile,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,partially,decreased cell size,developmental rate defective,stress response defective,cell growth defective,somatic clone,chemical sensitive,wild-type,visible,partially lethal - majority die,some die during pupal stage,body color defective" "wing,second instar larva,adult,larva,salivary gland,embryonic/larval fat body,egg & microtubule,egg,chaeta,supernumerary,mesothoracic tergum,trichogen cell" FBgn0085804 CR41571 - http://flybase.org/reports/FBgn0085804 pseudogene_attribute - - - CR41571 - CR41571 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039723 CG15522 - http://flybase.org/reports/FBgn0039723 protein_coding_gene - - - CG15522 - CG15522 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260761 CG42559 - http://flybase.org/reports/FBgn0260761 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG30182, CG42559" - CG42559 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262353 CR43051 - http://flybase.org/reports/FBgn0262353 non_protein_coding_gene - - - "GH14785, RE14176, psnoRNA:bun-a, CG43051, CR43051" - CR43051 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050335 CG30335 - http://flybase.org/reports/FBgn0050335 protein_coding_gene - - - CG30335 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001788 l(1)Mb7 lethal (1) Mb7 http://flybase.org/reports/FBgn0001788 - gene - - - l(1)Mb7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "macrochaeta,eye,arista" FBgn0023039 l(2)46Ed lethal (2) 46Ed http://flybase.org/reports/FBgn0023039 "FBgn0019717, FBgn0021827" gene - - - "L, 14.39, l(2)k16104, l(2)46CFk, l(2)46Ed" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0024281 Tabp Truncated actin binding protein http://flybase.org/reports/FBgn0024281 - gene - - - "DTABP, TABP, Tabp" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033093 CG3270 - http://flybase.org/reports/FBgn0033093 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000354057 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR023753 mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from biological aspect of ancestor with PANTHER:PTN000354502" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000354502 CG3270 "IPR006076:FAD dependent oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG3270 11-Aug-17 DroID_v2017_08 Drer\foxred1 - Cele\M04B2.4 Xtro\foxred1 Mmus\Foxred1 Hsap\FOXRED1 viable FBgn0032398 CG6766 - http://flybase.org/reports/FBgn0032398 protein_coding_gene - "retrograde protein transport, ER to cytosol ; GO:0030970 | inferred from biological aspect of ancestor with PANTHER:PTN000395729 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000395729" endoplasmic reticulum lumen ; GO:0005788 | inferred from biological aspect of ancestor with PANTHER:PTN000395729 endomembrane system ; GO:0012505 | inferred from direct assay "CG6766, cg6766" "IPR009011:Mannose-6-phosphate receptor binding domain, IPR012913:Glucosidase II beta subunit-like" CG6766 11-Aug-17 DroID_v2017_08 "Drer\os9, Drer\erlec1" Scer\YOS9 "Cele\Y105E8A.2, Cele\F48E8.4" "Xtro\erlec1, Xtro\os9" "Mmus\Os9, Mmus\Erlec1" "Hsap\ERLEC1, Hsap\OS9" viable FBgn0026197 noe noe http://flybase.org/reports/FBgn0026197 "FBgn0027686, FBgn0027690, FBgn0027717, FBgn0027750, FBgn0027772, FBgn0052172, FBgn0066008" non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32172, anon-EST:Posey101, anon-EST:Posey243, anon-EST:Posey292, anon-EST:Posey35, anon-EST:Posey151, anon-WO02059370.51, noe, Noe, CR32172" - CR32172 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0041341 Circe\gag Circe element gag http://flybase.org/reports/FBgn0041341 transposable_element_gene - - - "ORF1, Circe\gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060402 l(3)S131216 lethal (3) S131216 http://flybase.org/reports/FBgn0060402 gene - - - "1312/16, l(3)S131216" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267811 CR46136 - http://flybase.org/reports/FBgn0267811 non_protein_coding_gene - - - CR46136 - CR46136 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266069 CR44822 - http://flybase.org/reports/FBgn0266069 non_protein_coding_gene - - - CR44822 - CR44822 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001895 l(2)21Fa lethal (2) 21Fa http://flybase.org/reports/FBgn0001895 - gene - - - "l(2)neh-9, l(2)neh9, l(2)21Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0026671 l(1)G0119 lethal (1) G0119 http://flybase.org/reports/FBgn0026671 - gene - - - l(1)G0119 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0085357 CG34328 - http://flybase.org/reports/FBgn0085357 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34328 - CG34328 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038760 MED25 Mediator complex subunit 25 http://flybase.org/reports/FBgn0038760 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with UniProtKB:Q9W5P1 nervous system development ; GO:0007399 | inferred from mutant phenotype regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:Q9W5P1 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from sequence or structural similarity with UniProtKB:Q9W5P1 "Arc92, Med25, CG12254, LD07688, dARC92, MED25, dDrip97, med25" "IPR021394:Mediator complex, subunit Med25, PTOV activation and synapsin 2, IPR021419:Mediator complex, subunit Med25, von Willebrand factor type A" CG12254 11-Aug-17 DroID_v2017_08 Drer\med25 - - Xtro\med25 "Mmus\Med25, Mmus\Ptov1" "Hsap\MED25, Hsap\PTOV1" DRSC25776 K 0.961130692 1.903515822 FBgn0267982 CR46249 - http://flybase.org/reports/FBgn0267982 non_protein_coding_gene - - - CR46249 - CR46249 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067376 l(2)NC12 lethal (2) NC12 http://flybase.org/reports/FBgn0067376 gene - - - l(2)NC12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266848 wap wings apart http://flybase.org/reports/FBgn0266848 protein_coding_gene - positive regulation of hippo signaling ; GO:0035332 | inferred from mutant phenotype inferred from genetic interaction with ds positive regulation of growth ; GO:0045927 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000460287 "l(1)A-200, l(1)Q464, Q217, Q464, l(1)Q217, 22, 21, 20, 19, 16, 15, l(1)HM33, l(1)20Ab, wap, riq, Riq, CG14614, BcDNA:GM08142" "IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site" CG14614 11-Aug-17 DroID_v2017_08 Drer\dcaf7 Scer\YPL247C "Cele\swan-2, Cele\swan-1" Xtro\dcaf7 Mmus\Dcaf7 Hsap\DCAF7 FBgn0001141 gs grandchildless http://flybase.org/reports/FBgn0001141 - gene - - - gs - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female,female fertile,grandchildless,heat sensitive" "germline cell,female,male" FBgn0046685 Wsck Wsck http://flybase.org/reports/FBgn0046685 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | NOT inferred from key residues regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein phosphorylation ; GO:0006468 | NOT inferred from key residues innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 "WSCK, CG31127, BcDNA:SD05152, BcDNA:LD25626, Wsck" "IPR000719:Protein kinase domain, IPR002889:Carbohydrate-binding WSC, IPR003961:Fibronectin type III, IPR011009:Protein kinase-like domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR013783:Immunoglobulin-like fold" CG31127 11-Aug-17 DroID_v2017_08 "Drer\kita, Drer\kitb, Drer\kdrl, Drer\si:ch73-206d17.1, Drer\flt1, Drer\LOC569566, Drer\tec, Drer\fgfr1a, Drer\fgfr2, Drer\ret, Drer\si:dkey-14o18.6, Drer\pdgfrb, Drer\styk1, Drer\tek, Drer\csf1ra, Drer\pdgfrl, Drer\kdr, Drer\fgfr3, Drer\tie1, Drer\flt4, Drer\itk, Drer\csf1rb, Drer\flt3, Drer\fgfr4, Drer\fgfrl1b, Drer\si:ch211-167j9.5, Drer\txk, Drer\pdgfra, Drer\fgfrl1a" - Cele\T22B11.3 "Xtro\csf1r, Xtro\flt4, Xtro\fgfr2, Xtro\kdr, Xtro\styk1, Xtro\pdgfrl, Xtro\fgfr3, Xtro\fgfrl1, Xtro\pdgfra, Xtro\flt1, Xtro\fgfr1, Xtro\tie1, Xtro\fgfr4, Xtro\tek, Xtro\pdgfrl.2, Xtro\ret" "Mmus\Fgfr1, Mmus\Tec, Mmus\Flt1, Mmus\Flt3, Mmus\Fgfr2, Mmus\Ret, Mmus\Tek, Mmus\Pdgfrl, Mmus\Fgfr4, Mmus\Fgfrl1, Mmus\Pdgfrb, Mmus\Kdr, Mmus\Kit, Mmus\Pdgfra, Mmus\Itk, Mmus\Txk, Mmus\Tie1, Mmus\Csf1r, Mmus\Flt4, Mmus\Bmx, Mmus\Styk1, Mmus\Fgfr3" "Hsap\FGFR3, Hsap\FLT4, Hsap\FLT1, Hsap\TEC, Hsap\CSF1R, Hsap\TXK, Hsap\KIT, Hsap\FGFR1, Hsap\FLT3, Hsap\RET, Hsap\BMX, Hsap\PDGFRA, Hsap\PDGFRB, Hsap\KDR, Hsap\PDGFRL, Hsap\TIE1, Hsap\FGFR2, Hsap\ITK, Hsap\FGFRL1, Hsap\STYK1, Hsap\FGFR4, Hsap\TEK" "partially lethal - majority die,some die during pupal stage" FBgn0038473 Ns1 Nucleostemin 1 http://flybase.org/reports/FBgn0038473 protein_coding_gene GTPase activity ; GO:0003924 | inferred from direct assay ATPase activity ; GO:0016887 | inferred from direct assay GTP binding ; GO:0005525 | inferred from sequence or structural similarity with UniProtKB:Q811S9 cellular response to starvation ; GO:0009267 | inferred from expression pattern positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype ribosomal large subunit biogenesis ; GO:0042273 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay granular component ; GO:0001652 | inferred from direct assay "ns1, CG3983, dmNS1, NS1, Ns1" "IPR006073:GTP binding domain, IPR014813:Guanine nucleotide-binding protein-like 3, N-terminal domain, IPR030378:Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR023179:GTP-binding protein, orthogonal bundle domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3983 11-Aug-17 DroID_v2017_08 "Drer\gnl3l, Drer\gnl3" "Scer\NUG1, Scer\MRX8" Cele\nst-1 "Xtro\gnl3, Xtro\gnl3l" "Mmus\Gnl3l, Mmus\Gnl3" "Hsap\GNL3, Hsap\GNL3L, Hsap\GTPBP8" "lethal,melanotic mass phenotype,developmental rate defective,partially lethal - majority die,visible,some die during pupal stage" "melanotic mass | larval stage,head,eye,antenna,arista,midgut imaginal island | larval stage,nucleolus | larval stageda.G32,embryonic/larval salivary gland,mesothoracic tergum" FBgn0044007 Su(rst)B52 Su(rst)B52 http://flybase.org/reports/FBgn0044007 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B52, Su(rst)B52" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0030492 CG15754 - http://flybase.org/reports/FBgn0030492 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 - - CG15754 IPR000618:Insect cuticle protein CG15754 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\math-34, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable DRSC19719 EK 1.372118596 1.046749353 1.899991001 -0.230325249 1.635068152 -0.480060619 FBgn0043886 l(3)S118602b lethal (3) S118602b http://flybase.org/reports/FBgn0043886 gene - - - "1186/02, l(3)S118602, l(3)S118602b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0036895 ms(3)76Cc male sterile (3) 76Cc http://flybase.org/reports/FBgn0036895 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatid differentiation ; GO:0048515 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG9392, ms(3)76Cc" - CG9392 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable" FBgn0085198 CG34169 - http://flybase.org/reports/FBgn0085198 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34169 - CG34169 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011372 l(3)j5A1 lethal (3) j5A1 http://flybase.org/reports/FBgn0011372 - gene - - - l(3)j5A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0010665 l(2)10521 lethal (2) 10521 http://flybase.org/reports/FBgn0010665 - gene - - - l(2)10521 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036465 Rpn12R Regulatory particle non-ATPase 12-related http://flybase.org/reports/FBgn0036465 protein_coding_gene molecular_function ; GO:0003674 | no biological data available proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 proteasome assembly ; GO:0043248 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity with SGD:S000001948 "proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with Rpn12 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000273181" "Rpn12R, CG11552" "IPR006746:26S proteasome non-ATPase regulatory subunit Rpn12, IPR033464:CSN8/PSMD8/EIF3K" CG11552 11-Aug-17 DroID_v2017_08 Drer\psmd8 Scer\RPN12 Cele\rpn-12 Xtro\psmd8 Mmus\Psmd8 Hsap\PSMD8 FBgn0086306 bxPRE bithorax Polycomb Response Element http://flybase.org/reports/FBgn0086306 regulatory_region - - - "bxPRE, bx PRE, bx, BXD-PRE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267087 CR45531 - http://flybase.org/reports/FBgn0267087 non_protein_coding_gene - - - CR45531 - CR45531 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005368 Vel Velvet http://flybase.org/reports/FBgn0005368 - gene - - - Vel - - 11-Aug-17 DroID_v2017_08 - - - - - - eye FBgn0065378 l(2)SH1672 lethal (2) SH1672 http://flybase.org/reports/FBgn0065378 gene - - - "l(2)SH1672, l(2)SH2 1672" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011994 tRNA:Thr-AGT-1-6 transfer RNA:Threonine-AGT 1-6 http://flybase.org/reports/FBgn0011994 "FBgn0003833, FBgn0051590, FBgn0060046" tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "AE002708.trna48-ThrAGT, tRNA:T:AGT:AE002708-c, tRNA:thr:90Cb, CR31590, tRNA[[Thr]], chr3R.trna54-ThrAGT, tRNA-Thr-AGT-1-6, tRNA:Thr-AGT-1-6, tRNA:T:90Cb, ACU" - CR31590 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003400 sht short tarsi http://flybase.org/reports/FBgn0003400 - gene - - - sht - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,poor,visible" "pigment cell,leg,metatarsus,tarsal segment,macrochaeta,wing" FBgn0017358 l(3)L10 lethal (3) L10 http://flybase.org/reports/FBgn0017358 - gene - - - l(3)L10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069413 JJF170 JJF170 http://flybase.org/reports/FBgn0069413 gene - - - JJF170 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0002510 l(3)SG71 lethal (3) SG71 http://flybase.org/reports/FBgn0002510 - gene - - - l(3)SG71 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0051201 GluRIIE Glutamate receptor IIE http://flybase.org/reports/FBgn0051201 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 ionotropic glutamate receptor activity ; GO:0004970 | inferred by curator from GO:0008328 glutamate-gated calcium ion channel activity ; GO:0022849 | inferred from direct assay "calcium ion transport ; GO:0006816 | inferred from direct assay neuromuscular synaptic transmission ; GO:0007274 | inferred from expression pattern regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype synaptic transmission, glutamatergic ; GO:0035249 | inferred by curator from GO:0007274,GO:0008328 regulation of synaptic activity ; GO:0060025 | inferred from sequence or structural similarity with GluRIIA" ionotropic glutamate receptor complex ; GO:0008328 | inferred from mutant phenotype muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay "CG31201, GluR-IIE, GluRIIE, DmelGluRIIE" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR028082:Periplasmic binding protein-like I" CG31201 11-Aug-17 DroID_v2017_08 "Drer\gria2b, Drer\gria2a, Drer\grik2, Drer\grik1b, Drer\grik1a, Drer\si:ch211-251b21.1, Drer\LOC100334689, Drer\grik5, Drer\si:dkey-183j2.10, Drer\gria3a, Drer\LOC100331381, Drer\grik4, Drer\gria3b, Drer\gria4b, Drer\gria1a" - "Cele\glr-4, Cele\glr-3, Cele\glr-5, Cele\glr-8, Cele\glr-6" "Xtro\grik1, Xtro\gria3, Xtro\grik4, Xtro\gria4, Xtro\gria1, Xtro\grik5" "Mmus\Grik5, Mmus\Gria3, Mmus\Gria4, Mmus\Grik1, Mmus\Grik4, Mmus\Grik2, Mmus\Gria1, Mmus\Grik3, Mmus\Gria2" "Hsap\GRIK4, Hsap\GRIA1, Hsap\GRIA4, Hsap\GRIK5, Hsap\GRIK1, Hsap\GRIA2, Hsap\GRIA3, Hsap\GRIK2, Hsap\GRIK3" "lethal,recessive,paralytic,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage,viable" "neuromuscular junction,trichogen cell,mesothoracic tergum" DRSC13431 K -0.02878254 0.090746339 -0.203729171 -0.481634618 -2.009041546 -1.023059617 FBgn0053926 CG33926 - http://flybase.org/reports/FBgn0053926 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33926 - CG33926 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004536 l(4)102ABi lethal (4) 102ABi http://flybase.org/reports/FBgn0004536 - gene - - - "l(4)ABi, l(4)26, l(4)102ABi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0050161 CG30161 - http://flybase.org/reports/FBgn0050161 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG4856, BcDNA:AT15604, CG30161" - CG30161 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC22141 I -0.004883722 2.34870364 -0.631503477 0.187409464 -0.411070267 -0.669454045 FBgn0263445 CR43468 - http://flybase.org/reports/FBgn0263445 non_protein_coding_gene - - - CR43468 - CR43468 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020834 l(2)Mass Massachusetts http://flybase.org/reports/FBgn0020834 - gene - - - l(2)Mass - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038449 CG17562 - http://flybase.org/reports/FBgn0038449 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - CG17562 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG17562 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97m3.1, Drer\far1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR1, Hsap\FAR2" viable FBgn0067362 l(2)NC47 lethal (2) NC47 http://flybase.org/reports/FBgn0067362 gene - - - l(2)NC47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041148 hypnos-P hypnos-P http://flybase.org/reports/FBgn0041148 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "dRED, hypnos-P" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033949 CG10131 - http://flybase.org/reports/FBgn0033949 protein_coding_gene "3-hydroxyacyl-CoA dehydrogenase activity ; GO:0003857 | inferred from electronic annotation with InterPro:IPR006108, InterPro:IPR006176, InterPro:IPR006180" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006108, InterPro:IPR006176, InterPro:IPR006180, InterPro:IPR008927, InterPro:IPR013328 fatty acid metabolic process ; GO:0006631 | inferred from electronic annotation with InterPro:IPR006108, InterPro:IPR006176, InterPro:IPR006180 sleep ; GO:0030431 | inferred from expression pattern" - CG10131 "IPR006108:3-hydroxyacyl-CoA dehydrogenase, C-terminal, IPR006176:3-hydroxyacyl-CoA dehydrogenase, NAD binding, IPR006180:3-hydroxyacyl-CoA dehydrogenase, conserved site, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR016040:NAD(P)-binding domain, IPR013328:6-phosphogluconate dehydrogenase, domain 2" CG10131 11-Aug-17 DroID_v2017_08 Drer\cryl1 - "Cele\B0272.3, Cele\hacd-1, Cele\F54C8.1, Cele\Y71F9B.9" Xtro\cryl1 "Mmus\Cryl1, Mmus\Hadh" "Hsap\CRYL1, Hsap\HADH" FBgn0025922 l(3)76BDt lethal (3) 76BDt http://flybase.org/reports/FBgn0025922 - gene - - - l(3)76BDt - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027988 l(3)S128711 lethal (3) S128711 http://flybase.org/reports/FBgn0027988 gene - - - "1287/11, l(3)S128711" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0065797 l(2)SH0415 lethal (2) SH0415 http://flybase.org/reports/FBgn0065797 gene - - - "l(2)SH0415, l(2)SH2 0415" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027165 l(2)KC-A l(2)Karp and Cherbas A http://flybase.org/reports/FBgn0027165 - gene - - - "A, l(2)KC-A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023122 anon-10Al anon-10Al http://flybase.org/reports/FBgn0023122 - gene - - - "4, anon-10Al" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043384 EP566b EP566b http://flybase.org/reports/FBgn0043384 gene - - - "EP0566b, EP566b" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060625 l(3)S087602 lethal (3) S087602 http://flybase.org/reports/FBgn0060625 gene - - - "0876/02, l(3)S087602" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262529 CG43083 - http://flybase.org/reports/FBgn0262529 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43083 - CG43083 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037812 CG18545 - http://flybase.org/reports/FBgn0037812 protein_coding_gene - - - "CG18545, CG18545-PA" - CG18545 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053381 5SrRNA:CR33381 5SrRNA:CR33381 http://flybase.org/reports/FBgn0053381 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33381, 5SrRNA:CR33381" - CR33381 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039116 CG10375 - http://flybase.org/reports/FBgn0039116 protein_coding_gene - - - CG10375 IPR001623:DnaJ domain CG10375 11-Aug-17 DroID_v2017_08 "Drer\dnajc8, Drer\zgc:162816" Scer\CAJ1 Cele\dnj-30 Xtro\dnajc8 Mmus\Dnajc8 Hsap\DNAJC8 FBgn0034429 CG18607 - http://flybase.org/reports/FBgn0034429 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 CG18607 "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG18607 11-Aug-17 DroID_v2017_08 - - "Cele\M7.12, Cele\C28D4.7, Cele\R05H10.7, Cele\W02D7.5, Cele\F36D3.8, Cele\T10B5.4, Cele\anat-1, Cele\W02D7.4, Cele\R13D11.4, Cele\M7.8, Cele\C28D4.4, Cele\T09F5.10, Cele\F10G2.7, Cele\R05H10.1, Cele\C28D4.5" - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0031634 Ir25a Ionotropic receptor 25a http://flybase.org/reports/FBgn0031634 protein_coding_gene "ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR019594 extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 olfactory receptor activity ; GO:0004984 | contributes_to inferred from mutant phenotype ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model coreceptor activity ; GO:0015026 | inferred from mutant phenotype" ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern transmission of nerve impulse ; GO:0019226 | inferred from mutant phenotype "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR001508, InterPro:IPR019594 sensory dendrite ; GO:0071683 | colocalizes_with inferred from direct assay sensory dendrite ; GO:0071683 | inferred from direct assay cilium ; GO:0005929 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model" "Ir25a, CT35778, IR25a, CG15627, DmelIR25a" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG15627 11-Aug-17 DroID_v2017_08 "Drer\grid1b, Drer\grid2, Drer\grid1a" - Cele\glr-7 "Xtro\grid2, Xtro\grid1" "Mmus\Grid2, Mmus\Grid1" "Hsap\GRID2, Hsap\GRID1" "viable,fertile,neurophysiology defective" FBgn0037616 CG8136 - http://flybase.org/reports/FBgn0037616 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "anon-WO0140519.56, anon-WO0140519.254, CG8136" - CG8136 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary,wing" FBgn0000414 Dab Disabled http://flybase.org/reports/FBgn0000414 - protein_coding_gene sevenless binding ; GO:0005118 | inferred from physical interaction with UniProtKB:P13368 SH2 domain binding ; GO:0042169 | inferred from physical interaction with drk SH3 domain binding ; GO:0017124 | inferred from physical interaction with drk protein binding ; GO:0005515 | inferred from physical interaction with sev compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype clathrin-dependent endocytosis ; GO:0072583 | inferred from direct assay sevenless signaling pathway ; GO:0045500 | inferred from genetic interaction with sev dorsal closure ; GO:0007391 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype sevenless signaling pathway ; GO:0045500 | traceable author statement motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "dab, cDNA C, CG9695, Dab" "IPR006020:PTB/PI domain, IPR028761:Protein disabled, IPR011993:PH domain-like" CG9695 11-Aug-17 DroID_v2017_08 "Drer\dab1b, Drer\si:ch211-204c21.1, Drer\dab1a, Drer\dab2" - Cele\dab-1 "Xtro\dab1, Xtro\dab2" "Mmus\Dab1, Mmus\Dab2" "Hsap\DAB1, Hsap\DAB2" " embryonic stage | extended germ band , embryonic stage | early " " embryonic central nervous system

,

ubiquitous , mesoderm

" " embryonic stage , embryonic stage | stage 12 " " embryonic central nervous system

, peripheral nervous system

, somatic muscle

, mesoderm

" "locomotor behavior defective,neuroanatomy defective,neurophysiology defective,heat sensitive,viable,fertile,lethal,maternal effect,male sterile,partially lethal - majority die,female sterile" "rhabdomere R7,synapse,bouton,synaptic vesicle,synapseExel6130),synaptic vesicleExel6130),ganglion mother cell,intersegmental nerve branch ISNb of A1-7,maternal effect,segmental nerve branch SNa of A1-7,embryonic leading edge cell,embryo" FBgn0036532 CG13445 - http://flybase.org/reports/FBgn0036532 protein_coding_gene - - - CG13445 - CG13445 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC09992 K -0.660821959 -0.82212809 -0.474838254 -1.330480845 1.969374817 1.394102036 FBgn0020518 snoRNA:Me28S-G764 - http://flybase.org/reports/FBgn0020518 - snoRNA_gene - - nucleolus ; GO:0005730 | inferred from sequence or structural similarity "snoRNA:21, U21, SnoRNA U21, CR32907, snoRNA:Me28S-G764, Me28S-G764(U21), snoRNA:U21" - CR32907 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036624 RAF2 RING-associated factor 2 http://flybase.org/reports/FBgn0036624 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000812953" regulation of multicellular organismal development ; GO:2000026 | inferred from biological aspect of ancestor with PANTHER:PTN000812953 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000812953 "PcG protein complex ; GO:0031519 | inferred from physical interaction with Sce, Psc" "CG4689, dRAF2, CG4877, RAF2" "IPR002893:Zinc finger, MYND-type" CG4877 11-Aug-17 DroID_v2017_08 - - Cele\pis-1 - Mmus\Zmynd10 Hsap\ZMYND10 viable FBgn0021945 l(2)k10609 lethal (2) k10609 http://flybase.net/reports/FBgn0021945.html gene P996 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0044337 3S18\ORF 3S18 element ORF http://flybase.org/reports/FBgn0044337 transposable_element_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001969" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001969 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - 3S18\ORF "IPR021109:Aspartic peptidase domain, IPR001878:Zinc finger, CCHC-type, IPR001584:Integrase, catalytic core, IPR001969:Aspartic peptidase, active site, IPR008737:Peptidase aspartic, putative, IPR008042:Retrotransposon, Pao, IPR012337:Ribonuclease H-like domain, IPR005312:Protein of unknown function DUF1759" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265313 CG44286 - http://flybase.org/reports/FBgn0265313 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44286, CG8788-3'utr" - CG44286 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040208 Kat60 Katanin 60 http://flybase.org/reports/FBgn0040208 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR028596 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 microtubule-severing ATPase activity ; GO:0008568 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 microtubule-severing ATPase activity ; GO:0008568 | inferred from direct assay myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule-severing ATPase activity ; GO:0008568 | inferred from mutant phenotype" cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype microtubule depolymerization ; GO:0007019 | inferred from direct assay microtubule severing ; GO:0051013 | inferred from direct assay wing disc development ; GO:0035220 | inferred from genetic interaction with Bx inferred from genetic interaction with ap microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype microtubule severing ; GO:0051013 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype dendrite development ; GO:0016358 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp negative regulation of cell migration ; GO:0030336 | inferred from mutant phenotype microtubule severing ; GO:0051013 | inferred from sequence or structural similarity with NCBI_gi:3283072 centrosome ; GO:0005813 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay cytoplasmic microtubule ; GO:0005881 | inferred from direct assay cell leading edge ; GO:0031252 | inferred from direct assay katanin complex ; GO:0008352 | inferred from sequence or structural similarity with NCBI_gi:3283072 cell cortex ; GO:0005938 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 "katanin60-dm, DmCG10229, CG10229, Katanin-60, Dm-Kat60, katanin-60, Katanin 60, kat60, Kat60" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR015415:Vps4 oligomerisation, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR028596:Katanin p60 subunit A1" CG10229 11-Aug-17 DroID_v2017_08 "Drer\vps4b, Drer\katnal2, Drer\katna1, Drer\katnal1, Drer\spast, Drer\fignl1, Drer\fign" "Scer\VPS4, Scer\SAP1" "Cele\figl-1, Cele\vps-4, Cele\mei-1, Cele\spas-1" "Xtro\spast, Xtro\katnal1, Xtro\vps4b, Xtro\fign, Xtro\katna1, Xtro\vps4a, Xtro\fignl1" "Mmus\Vps4a, Mmus\Katna1, Mmus\Fignl1, Mmus\Katnal2, Mmus\Fign, Mmus\Katnal1, Mmus\Vps4b, Mmus\Spast" "Hsap\VPS4A, Hsap\KATNAL2, Hsap\KATNA1, Hsap\SPAST, Hsap\VPS4B, Hsap\KATNAL1" "lethal,majority die during larval stage,some die during pupal stage,neuroanatomy defective,neurophysiology defective,viable" "NMJ bouton,class IV dendritic arborizing neuron,dendritic tree,microtubule,NMJ bouton | third instar larval stage,microtubuleC57,dendritic treeppk.PG,mushroom body & axon7B,Kenyon cell,mushroom body alpha-lobe,adult mushroom body" DRSC12378 K -0.360806805 0.850827234 -0.007597754 0.448088556 -1.886065802 0.748121361 FBgn0267214 CR45654 - http://flybase.org/reports/FBgn0267214 non_protein_coding_gene - - - CR45654 - CR45654 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023104 anon-23Ab anon-23Ab http://flybase.org/reports/FBgn0023104 - gene - - - anon-23Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052586 CG32586 - http://flybase.org/reports/FBgn0052586 protein_coding_gene - - - CG32586 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22518 IE 1.688565289 -0.139529859 0.53069159 1.533620258 0.457060593 -0.060836528 FBgn0030054 Caf1-180 "Chromatin assembly factor 1, p180 subunit" http://flybase.org/reports/FBgn0030054 protein_coding_gene histone binding ; GO:0042393 | contributes_to inferred by curator from GO:0033186 response to gamma radiation ; GO:0010332 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype nucleosome organization ; GO:0034728 | inferred from mutant phenotype nucleosome assembly ; GO:0006334 | inferred from direct assay multicellular organism growth ; GO:0035264 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype CAF-1 complex ; GO:0033186 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "NURF, p180, CG12109, Caf1-180, CAF1-180, CAF-1 p180, dCAF-1-p180, caf1-180, CAF1p180, CAF1-p180, dCAF-1-180, Caf-180, P180" "IPR029105:Chromatin assembly factor 1 subunit A, C-terminal, IPR022043:Chromatin assembly factor 1 subunit A" CG12109 11-Aug-17 DroID_v2017_08 Drer\chaf1a Scer\RLF2 Cele\chaf-1 Xtro\chaf1a Mmus\Chaf1a Hsap\CHAF1A "lethal,recessive,suppressor of variegation,dominant,visible,increased cell death,size defective,female sterile germline-dependent,germline clone,somatic clone,radiation sensitive,lethal - all die before end of larval stage,some die during larval stage,wild-type,partially lethal - majority die,some die during pupal stage,endomitotic cell cycle defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "eye,wing,fat body,somatic clone,ommatidium,trichogen cell,mesothoracic tergum,imaginal disc,embryonic/larval salivary gland" FBgn0085701 CG41574 - http://flybase.org/reports/FBgn0085701 protein_coding_gene - - - CG41574 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035532 CG15014 - http://flybase.org/reports/FBgn0035532 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN001781429 tRNA modification ; GO:0006400 | inferred from biological aspect of ancestor with PANTHER:PTN001781429 - CG15014 IPR004114:THUMP domain CG15014 11-Aug-17 DroID_v2017_08 Drer\thumpd1 Scer\TAN1 Cele\W02G9.3 Xtro\thumpd1 Mmus\Thumpd1 Hsap\THUMPD1 viable FBgn0035554 CG13721 - http://flybase.org/reports/FBgn0035554 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13721 - CG13721 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035325 CG13806 - http://flybase.org/reports/FBgn0035325 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG13806 IPR002557:Chitin binding domain CG13806 11-Aug-17 DroID_v2017_08 - - "Cele\phat-4, Cele\F35E8.6, Cele\F35E8.1, Cele\F35E8.4, Cele\F16H6.3, Cele\T05B4.10, Cele\F07C4.10, Cele\T05B4.12, Cele\Y46H3D.8, Cele\F07C4.11, Cele\T05B4.13, Cele\T05B4.9, Cele\phat-5, Cele\R02F2.4, Cele\F26D2.13" - - - "viable,visible" trichogen cell FBgn0267450 CR45800 - http://flybase.org/reports/FBgn0267450 non_protein_coding_gene - - - "CR45800, Mgn4103" - CR45800 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085654 CG41493 - http://flybase.org/reports/FBgn0085654 protein_coding_gene - - - CG41493 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086398 BG02348 - http://flybase.org/reports/FBgn0086398 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02348 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0035422 RpL28 Ribosomal protein L28 http://flybase.org/reports/FBgn0035422 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR002672 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002672 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR002672 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG12740, L28, BcDNA:GH04183, anon-WO0118547.321, RpL28, GH04183p, chr3L:3205394..3205484" "IPR002672:Ribosomal protein L28e, IPR029004:Ribosomal L28e/Mak16" CG12740 11-Aug-17 DroID_v2017_08 Drer\rpl28 - Cele\rpl-28 Xtro\rpl28 Mmus\Rpl28 Hsap\RPL28 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC08293 IEK -1.886652918 -1.006913507 1.155928268 -3.536290469 -0.839979592 1.535077813 FBgn0267715 CR46048 - http://flybase.org/reports/FBgn0267715 non_protein_coding_gene - - - "CR46048, Mgn95005" - CR46048 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001247 Ide Insulin degrading metalloproteinase http://flybase.org/reports/FBgn0001247 - protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001431 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011237, InterPro:IPR011249" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001431 response to dietary excess ; GO:0002021 | inferred from mutant phenotype insulin catabolic process ; GO:1901143 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype regulation of trehalose metabolic process ; GO:0090062 | inferred from mutant phenotype regulation of oviposition ; GO:0046662 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype regulation of trehalose metabolic process ; GO:0090062 | inferred from direct assay regulation of developmental growth ; GO:0048638 | inferred from mutant phenotype negative regulation of phosphatidylinositol 3-kinase signaling ; GO:0014067 | inferred from genetic interaction with Pten inferred from genetic interaction with foxo defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:5381 inferred from sequence model cytoplasm ; GO:0005737 | inferred from direct assay "IDE, CG5517, dIDE, Ide, dIde, dlde, ide, dide" "IPR001431:Peptidase M16, zinc-binding site, IPR007863:Peptidase M16, C-terminal, IPR011765:Peptidase M16, N-terminal, IPR011249:Metalloenzyme, LuxS/M16 peptidase-like, IPR032632:Peptidase M16, middle/third domain" CG5517 11-Aug-17 DroID_v2017_08 "Drer\nrd1b, Drer\nrd1a, Drer\ide" "Scer\AXL1, Scer\STE23" "Cele\Y70C5C.1, Cele\C28F5.4, Cele\C02G6.1, Cele\F44E7.4, Cele\C02G6.2" "Xtro\ide, Xtro\nrdc" "Mmus\Nrd1, Mmus\Ide" "Hsap\IDE, Hsap\NRDC" "partially lethal - majority die,small body,long lived,female limited,short lived,large body,viable,size defective,decreased cell size,decreased cell number,developmental rate defective,nutrition conditional,fertile" "hemolymph,wing,salivary gland,wing disc,dorsal compartment,posterior compartment" FBgn0003685 tf trefoil http://flybase.org/reports/FBgn0003685 - gene - - - tf - - 11-Aug-17 DroID_v2017_08 - - - - - - body color defective scutellum FBgn0031925 Cyp4d21 Cyp4d21 http://flybase.org/reports/FBgn0031925 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 mating ; GO:0007618 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay "sxe1, CG6730, 4d21, Cyp4d21, cyp4d21, CYP4d21" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV, IPR017972:Cytochrome P450, conserved site" CG6730 11-Aug-17 DroID_v2017_08 "Drer\cyp51, Drer\cyp3c4, Drer\cyp26b1, Drer\cyp20a1, Drer\cyp46a1.4, Drer\LOC100329425, Drer\cyp46a1.2, Drer\cyp46a1.1, Drer\cyp4v7, Drer\cyp3c2, Drer\cyp3a65, Drer\cyp46a1.3, Drer\cyp3c1, Drer\cyp26c1, Drer\cyp4f3, Drer\cyp4v8, Drer\cyp19a1a, Drer\cyp3c3, Drer\cyp4t8, Drer\cyp26a1, Drer\cyp19a1b" "Scer\ERG5, Scer\ERG11, Scer\DIT2" "Cele\cyp-13A10, Cele\cyp-13A11, Cele\cyp-13A4, Cele\cyp-13A1, Cele\cyp-13A5, Cele\cyp-13A12, Cele\cyp-37A1, Cele\cyp-13A7, Cele\cyp-25A4, Cele\cyp-13A3, Cele\cyp-32A1, Cele\cyp-25A3, Cele\cyp-13A8, Cele\cyp-29A4, Cele\cyp-29A2, Cele\cyp-32B1, Cele\cyp-31A3, Cele\cyp-25A1, Cele\cyp-25A2, Cele\cyp-42A1, Cele\cyp-31A5, Cele\cyp-29A3, Cele\cyp-31A2, Cele\cyp-37B1" "Xtro\LOC100487918, Xtro\mgc108213, Xtro\LOC100488227, Xtro\cyp19a1, Xtro\cyp4f22, Xtro\cyp4b1, Xtro\cyp20a1, Xtro\cyp26b1, Xtro\cyp4b1.2, Xtro\cyp26c1, Xtro\cyp4v2, Xtro\cyp26a1, Xtro\cyp4f2" "Mmus\Cyp4f13, Mmus\Cyp46a1, Mmus\Cyp4a10, Mmus\Cyp4b1, Mmus\Cyp4a12b, Mmus\Cyp39a1, Mmus\Cyp3a44, Mmus\Cyp4f16, Mmus\Cyp3a59, Mmus\Cyp3a57, Mmus\Cyp4f37, Mmus\Cyp4f40, Mmus\Cyp4a30b, Mmus\Cyp26b1, Mmus\Cyp4a32, Mmus\Cyp3a41b, Mmus\Cyp19a1, Mmus\Cyp4f17, Mmus\Cyp3a16, Mmus\Cyp3a13, Mmus\Cyp20a1, Mmus\Cyp3a41a, Mmus\Cyp4f14, Mmus\Cyp4v3, Mmus\Cyp26a1, Mmus\Cyp3a11, Mmus\Cyp4a31, Mmus\Cyp4f18, Mmus\Cyp51, Mmus\Cyp4a12a, Mmus\Cyp4x1, Mmus\Cyp4a14, Mmus\Cyp3a25, Mmus\Cyp4a29, Mmus\Cyp4f15, Mmus\Cyp26c1, Mmus\Cyp4f39" "Hsap\CYP4F2, Hsap\CYP4F3, Hsap\CYP4V2, Hsap\CYP26C1, Hsap\CYP26A1, Hsap\CYP3A4, Hsap\CYP26B1, Hsap\CYP4X1, Hsap\CYP20A1, Hsap\CYP4B1, Hsap\CYP3A43, Hsap\CYP4Z1, Hsap\CYP4F22, Hsap\CYP4A22, Hsap\CYP4F12, Hsap\CYP4F11, Hsap\CYP46A1, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\CYP4F8, Hsap\CYP39A1, Hsap\CYP19A1, Hsap\CYP4A11" "viable,courtship behavior defective,male,mating defective,recessive" FBgn0261568 CG42682 - http://flybase.org/reports/FBgn0261568 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42682 - CG42682 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022097 Vha36-1 Vacuolar H[+] ATPase 36kD subunit 1 http://flybase.org/reports/FBgn0022097 "FBgn0034028, FBgn0045927, FBgn0045934, FBgn0045935, FBgn0066035" protein_coding_gene "ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from electronic annotation with InterPro:IPR002699 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181" proton transport ; GO:0015992 | inferred from sequence or structural similarity ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 "vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD:S000000777 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay" "VhaD, vha36, l(2)k07207, CG8186, anon-WO02059370.27, anon-WO0153538.28, anon-WO0153538.21, anon-WO0153538.20, vha36-1, Vha36, Vha36-1, ATP6V1D" "IPR002699:ATPase, V1 complex, subunit D" CG8186 11-Aug-17 DroID_v2017_08 "Drer\alkbh1, Drer\atp6v1d" Scer\VMA8 Cele\vha-14 "Xtro\alkbh1, Xtro\atp6v1d" "Mmus\Atp6v1d, Mmus\Alkbh1" Hsap\ATP6V1D "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" Malpighian tubule FBgn0266060 Su(var)333 - http://flybase.org/reports/FBgn0266060 gene - - - "Su(var)333, 333" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0266697 CR45187 - http://flybase.org/reports/FBgn0266697 non_protein_coding_gene - - - CR45187 - CR45187 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037712 CG16789 - http://flybase.org/reports/FBgn0037712 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 - - CG16789 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site, IPR003959:ATPase, AAA-type, core" CG16789 11-Aug-17 DroID_v2017_08 "Drer\fign, Drer\fignl1, Drer\si:dkey-157g16.6, Drer\spast, Drer\iqca1, Drer\zgc:153738" "Scer\SAP1, Scer\YTA6" - "Xtro\iqca1, Xtro\spast, Xtro\fignl1, Xtro\fign" "Mmus\Iqca, Mmus\4931409K22Rik, Mmus\Spast, Mmus\Fign, Mmus\Fignl1, Mmus\Fignl2" "Hsap\IQCA1, Hsap\IQCA1L, Hsap\FIGNL1, Hsap\FIGN, Hsap\SPAST" viable FBgn0003019 Ota3 Olfactory trap abnormal 3 http://flybase.org/reports/FBgn0003019 - gene molecular_function ; GO:0003674 | no biological data available chemosensory behavior ; GO:0007635 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "ota3, Ota3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,dominant,partially" FBgn0259605 B0256 - http://flybase.org/reports/FBgn0259605 gene - - - B0256 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing vein L3" FBgn0029733 CG6927 - http://flybase.org/reports/FBgn0029733 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 chloride channel activity ; GO:0005254 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001055382 "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006029, InterPro:IPR006201" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201" "CG6927, Lcch-4D, CT21430" "IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000:Neurotransmitter-gated ion-channel, conserved site" CG6927 11-Aug-17 DroID_v2017_08 "Drer\glrba, Drer\glra3, Drer\glra4a, Drer\glra4b, Drer\glrbb, Drer\glra2, Drer\glra1" - "Cele\glc-3, Cele\lgc-47, Cele\lgc-55, Cele\acc-1, Cele\acc-3, Cele\glc-1, Cele\lgc-48, Cele\acc-2, Cele\lgc-49, Cele\lgc-51, Cele\glc-4, Cele\avr-15, Cele\lgc-46, Cele\avr-14, Cele\lgc-52, Cele\lgc-50, Cele\ggr-3, Cele\glc-2, Cele\lgc-53, Cele\mod-1, Cele\acc-4, Cele\lgc-54" "Xtro\glra3, Xtro\glra1, Xtro\glra2, Xtro\glrb" "Mmus\Glrb, Mmus\Glra1, Mmus\Glra4, Mmus\Glra2, Mmus\Glra3" "Hsap\GLRB, Hsap\GLRA1, Hsap\GLRA3, Hsap\GLRA4, Hsap\GLRA2" lethal FBgn0264601 CR43950 - http://flybase.org/reports/FBgn0264601 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43950, CR43950" - CR43950 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065492 l(2)SH1230 lethal (2) SH1230 http://flybase.org/reports/FBgn0065492 gene - - - l(2)SH1230 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023521 CG3587 - http://flybase.org/reports/FBgn0023521 - protein_coding_gene - - - "EG:39E1.2, CG3587" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013641:Protein KTI12/L-seryl-tRNA(Sec) kinase" CG3587 11-Aug-17 DroID_v2017_08 Drer\kti12 Scer\KTI12 Cele\Y57G11C.43 Xtro\kti12 Mmus\Kti12 Hsap\KTI12 "lethal,recessive,viable" FBgn0262300 mir-988 mir-988 stem loop http://flybase.org/reports/FBgn0262300 miRNA_gene - - - "miR-20071, mir-988, miR-988, 988, CR43007, miR988, dme-miR-988" - CR43007 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031652 jet jetlag http://flybase.org/reports/FBgn0031652 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from genetic interaction with tim SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "jet, JET, CG8873, FBXL15" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR006553:Leucine-rich repeat, cysteine-containing subtype" CG8873 11-Aug-17 DroID_v2017_08 Drer\fbxl15 Scer\GRR1 - Xtro\fbxl15 Mmus\Fbxl15 Hsap\FBXL15 "photoperiod response variant,locomotor rhythm defective,partially lethal - majority die,some die during pupal stage" FBgn0085770 CR40734 - http://flybase.org/reports/FBgn0085770 rRNA_gene - - - CR40734 - CR40734 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033273 Gasz Gasz http://flybase.org/reports/FBgn0033273 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "BEST:LD05795, gasz, CG2183, Gasz, GASZ, dGasz" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR013761:Sterile alpha motif/pointed domain" CG2183 11-Aug-17 DroID_v2017_08 Drer\asz1 Scer\NAS6 Cele\T16G1.9 Xtro\asz1 "Mmus\Anks3, Mmus\Asz1" "Hsap\ANKS3, Hsap\ASZ1" "viable,visible,female sterile" "chaeta,trichogen cell,supernumerary" FBgn0036125 Iyd Iodotyrosine deiodinase http://flybase.org/reports/FBgn0036125 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR016152 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR000415 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR016152 - "Iyd, dmIYD, CG6279, CG6279-PB" "IPR000415:Nitroreductase-like, IPR016152:Phosphotransferase/anion transporter, IPR029479:Nitroreductase" CG6279 11-Aug-17 DroID_v2017_08 Drer\si:ch211-286f9.2 - Cele\sup-18 Xtro\iyd Mmus\Iyd Hsap\IYD viable FBgn0034060 CG8370 - http://flybase.org/reports/FBgn0034060 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000498719 endomembrane system ; GO:0012505 | inferred from direct assay CG8370 "IPR013783:Immunoglobulin-like fold, IPR022113:Transmembrane protein 131-like" CG8370 11-Aug-17 DroID_v2017_08 "Drer\tmem131, Drer\si:ch211-208h7.4" - Cele\C27F2.8 Xtro\kiaa0922 "Mmus\Tmem131, Mmus\D930015E06Rik" "Hsap\KIAA0922, Hsap\TMEM131" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0054046 CR34046 - http://flybase.org/reports/FBgn0054046 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1091, HDC16610, CG34046, CR34046" - CR34046 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260803 EP2-1080 - http://flybase.org/reports/FBgn0260803 gene - - - EP2-1080 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003505 Srf Surf wings http://flybase.org/reports/FBgn0003505 - gene - - - Srf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable,fertile" wing FBgn0011173 l(1)291-11 lethal (1) 291-11 http://flybase.org/reports/FBgn0011173 FBgn0010199 gene - - - "291-11, l(1)291-11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029175 Ext2 Ext2 http://flybase.org/reports/FBgn0029175 protein_coding_gene glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ; GO:0050508 | inferred from sequence or structural similarity with UniProtKB:O77783 glucuronosyltransferase activity ; GO:0015020 | non-traceable author statement acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with ttv N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity ; GO:0050509 | inferred from sequence or structural similarity with UniProtKB:O77783 "heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement chondroitin sulfate biosynthetic process ; GO:0030206 | inferred from mutant phenotype heparin biosynthetic process ; GO:0030210 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from direct assay decapentaplegic signaling pathway ; GO:0008101 | inferred from mutant phenotype N-acetylglucosamine metabolic process ; GO:0006044 | inferred from sequence or structural similarity with UniProtKB:O77783 glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR015338 endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "sotv, DEXT2, Sotv, DExt2, CG33038, CG8433, BcDNA:GH02288, Ext2, dExt2" "IPR004263:Exostosin-like, IPR015338:Exostosin , C-terminal, IPR029044:Nucleotide-diphospho-sugar transferases" CG8433 11-Aug-17 DroID_v2017_08 "Drer\atp5s, Drer\ext2, Drer\ext1b, Drer\ext1c, Drer\ext1a, Drer\LOC101885478, Drer\extl2" - "Cele\rib-2, Cele\rib-1, Cele\C05C8.1" "Xtro\atp5s, Xtro\ext1, Xtro\ext2, Xtro\extl2" "Mmus\Ext1, Mmus\Ext2, Mmus\Extl2, Mmus\Extl1, Mmus\Atp5s" "Hsap\EXTL2, Hsap\EXTL1, Hsap\EXT2, Hsap\ATP5S, Hsap\EXT1" "segment polarity phenotype,germline clone,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing vein L3,somatic clone,wing vein L4,wing margin,wing margin bristle,ectopic,cell non-autonomous,denticle,germline clone,rescuable maternal effect,embryonic/first instar larval cuticle,wing,wing vein,maternal effect,denticle belt,eye,leg,imaginal disc,wing disc" FBgn0050364 hubl hug-bell http://flybase.org/reports/FBgn0050364 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG2149, anon-WO0140519.168, hubl, CG30364" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG30364 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039976 CG17920 - http://flybase.org/reports/FBgn0039976 protein_coding_gene - - - CG17920 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038524 sll slalom http://flybase.org/reports/FBgn0038524 protein_coding_gene 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity ; GO:0046964 | inferred from direct assay 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity ; GO:0046964 | inferred from biological aspect of ancestor with PANTHER:PTN000081360 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR013657 3'-phosphoadenosine 5'-phosphosulfate transport ; GO:0046963 | inferred from direct assay oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from mutant phenotype integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 Golgi apparatus ; GO:0005794 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 "CG7623, 1422/14, l(3)S142214, anon-WO0172774.85, anon-WO0118547.555, sll, Sll" IPR013657:UAA transporter CG7623 11-Aug-17 DroID_v2017_08 "Drer\slc35b2, Drer\slc35b1" Scer\HUT1 "Cele\pst-1, Cele\hut-1" "Xtro\slc35b2, Xtro\slc35b1" "Mmus\Slc35b2, Mmus\Slc35b1" "Hsap\SLC35B1, Hsap\SLC35B2" "viable,lethal,recessive,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "wing vein L5,wing,wing vein,ectopic,somatic clone,embryonic/first instar larval cuticle,denticle belt,1st posterior cell,wing vein L2,embryonic ventral epidermis,maternal effect" FBgn0034408 sano serrano http://flybase.org/reports/FBgn0034408 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "establishment of ommatidial planar polarity ; GO:0042067 | inferred from direct assay regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype" apical cortex ; GO:0045179 | inferred from direct assay "CG12758, sano" IPR025946:CABIT domain CG12758 11-Aug-17 DroID_v2017_08 Drer\nupl2 - - - Mmus\Nupl2 Hsap\NUPL2 "planar polarity defective,visible,somatic clone,cell non-autonomous,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,viable" "embryonic/larval dorsal trunk,macrochaeta,wing,wing hair,1st posterior cell,ommatidium,eye photoreceptor cell,somatic clone,embryonic/larval salivary gland,cell non-autonomous" FBgn0037615 CG11760 - http://flybase.org/reports/FBgn0037615 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:25018 cilium ; GO:0005929 | inferred from sequence or structural similarity with HGNC:25018 "BcDNA:LD16427, CG11760" "IPR019184:Uncharacterised protein family, transmembrane-17" CG11760 11-Aug-17 DroID_v2017_08 Drer\si:rp71-1d10.5 - "Cele\mks-2, Cele\C30B5.6" Xtro\tmem216 "Mmus\Tmem216, Mmus\Tmem80" "Hsap\TMEM216, Hsap\TMEM80" "partially lethal - majority die,some die during pupal stage,viable" FBgn0000388 Curl Curl http://flybase.org/reports/FBgn0000388 - gene - - - "Coi, Cd, Curl, Cu" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal,recessive,dominant,fertile" wing FBgn0036090 CG8009 - http://flybase.org/reports/FBgn0036090 protein_coding_gene - positive regulation of triglyceride biosynthetic process ; GO:0010867 | inferred from sequence or structural similarity with UniProtKB:Q8N9A8 positive regulation of protein dephosphorylation ; GO:0035307 | inferred from sequence or structural similarity with UniProtKB:Q8N9A8 Nem1-Spo7 phosphatase complex ; GO:0071595 | inferred from sequence or structural similarity with UniProtKB:Q8N9A8 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q8N9A8 nuclear membrane ; GO:0031965 | inferred from sequence or structural similarity with UniProtKB:Q8N9A8 "BcDNA:LD14173, CG8009" IPR019168:Nuclear envelope phosphatase-regulatory subunit 1 CG8009 11-Aug-17 DroID_v2017_08 Drer\cnep1r1 - Cele\nepr-1 Xtro\cnep1r1 Mmus\Cnep1r1 Hsap\CNEP1R1 viable FBgn0264531 l(3)ff30 - http://flybase.org/reports/FBgn0264531 gene - - - l(3)ff30 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0037727 CG8358 - http://flybase.org/reports/FBgn0037727 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG8358 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR030082:Neprilysin-21" CG8358 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\ece2b, Drer\mmel1, Drer\phex" - "Cele\nep-12, Cele\nep-8, Cele\nep-23, Cele\nep-17, Cele\nep-9, Cele\nep-10, Cele\nep-5, Cele\nep-16, Cele\nep-20, Cele\nep-6, Cele\nep-19, Cele\nep-13, Cele\nep-18, Cele\nep-24, Cele\nep-3, Cele\nep-7, Cele\nep-26, Cele\nep-21" "Xtro\ece1, Xtro\ece2, Xtro\mmel1, Xtro\ecel1" "Mmus\Kel, Mmus\Mmel1, Mmus\Phex, Mmus\Ece2, Mmus\Ece1, Mmus\Mme, Mmus\Ecel1" "Hsap\MME, Hsap\ECE1, Hsap\ECE2, Hsap\KEL, Hsap\PHEX, Hsap\MMEL1, Hsap\ECEL1" "viable,fertile" FBgn0032143 CG4017 - http://flybase.org/reports/FBgn0032143 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG4017 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG4017 11-Aug-17 DroID_v2017_08 "Drer\cpb1, Drer\cpa5, Drer\cpa6, Drer\cpa2, Drer\cpb2, Drer\cpo, Drer\cpa4, Drer\cpa1" Scer\ECM14 "Cele\F02D8.4, Cele\Y59C2A.1, Cele\Y47G6A.19, Cele\ZC434.9, Cele\Y18H1A.9, Cele\T06A4.1, Cele\W01A8.6, Cele\T06A4.3, Cele\suro-1" "Xtro\LOC100487462, Xtro\cpa1, Xtro\cpo, Xtro\cpb1, Xtro\cpb2, Xtro\cpa3" "Mmus\Cpa3, Mmus\Cpa4, Mmus\Cpa5, Mmus\Cpb2, Mmus\Cpa1, Mmus\Cpb1, Mmus\Cpa6, Mmus\Cpa2" "Hsap\CPA1, Hsap\CPA3, Hsap\CPA2, Hsap\CPA6, Hsap\CPB2, Hsap\CPA5, Hsap\CPA4, Hsap\CPB1, Hsap\CPO" viable FBgn0035218 CG9173 - http://flybase.org/reports/FBgn0035218 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay - CG9173 - CG9173 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050282 CG30282 - http://flybase.org/reports/FBgn0050282 protein_coding_gene - - - "BcDNA:LD42239, CG30282" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22227 K 0.133208971 0.191836971 -0.427759086 0.085412857 -0.198074442 1.509068354 FBgn0028204 l(3)S014308 lethal (3) S014308 http://flybase.org/reports/FBgn0028204 gene - - - "0143/08, l(3)S014308" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0036783 CheA75a Chemosensory protein A 75a http://flybase.org/reports/FBgn0036783 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheA29a extracellular region ; GO:0005576 | inferred from sequence model "CG7313, BcDNA:HL02449, CheA75a" IPR010512:Protein of unknown function DUF1091 CG7313 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0084965 2.3.26 2.3.26 http://flybase.org/reports/FBgn0084965 gene - - - 2.3.26 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0003297 rubb rubbish http://flybase.org/reports/FBgn0003297 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "rub, rubb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0069959 CG41058 - http://flybase.org/reports/FBgn0069959 protein_coding_gene - - - CG41058 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033439 CG1773 - http://flybase.org/reports/FBgn0033439 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP74, CG1773" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG1773 11-Aug-17 DroID_v2017_08 Drer\masp2 - "Cele\try-3, Cele\svh-1" - "Mmus\Egfbp2, Mmus\Klk1b9, Mmus\C2, Mmus\Klk1b5" - "viable,visible" trichogen cell FBgn0259190 Ir7d Ionotropic receptor 7d http://flybase.org/reports/FBgn0259190 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG15327, DmelIR7d, CG42294, Ir7d, IR7d" - CG42294 11-Aug-17 DroID_v2017_08 "Drer\LOC100537813, Drer\grid1a, Drer\grid1b" - Cele\glr-8 - "Mmus\Grik4, Mmus\Grid1" "Hsap\GRID2, Hsap\GRID1, Hsap\GRIK3, Hsap\GRIN2C" FBgn0062674 EP2448 EP2448 http://flybase.org/reports/FBgn0062674 gene - - - "EP(2)2448, EP2448" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052369 CG32369 - http://flybase.org/reports/FBgn0052369 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from biological aspect of ancestor with PANTHER:PTN000360213 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000360213 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000360213 positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from biological aspect of ancestor with PANTHER:PTN000360213 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000360213 "CG7388, CG13684, CG32369" "IPR001841:Zinc finger, RING-type, IPR003111:Lon, substrate-binding domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR017907:Zinc finger, RING-type, conserved site, IPR019734:Tetratricopeptide repeat, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015947:PUA-like domain" CG32369 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-440b2.1, Drer\si:dkey-250l23.4, Drer\trim35-40, Drer\rnf180, Drer\rnf168, Drer\lonrf1l, Drer\lonrf1, Drer\LOC567909, Drer\btr32" Scer\RAD18 "Cele\T02C1.1, Cele\T02C1.2" "Xtro\bfar, Xtro\rnf168, Xtro\LOC105945814, Xtro\lonrf2" "Mmus\Lonrf2, Mmus\Rnf180, Mmus\Lonrf3, Mmus\Rad18, Mmus\Lonrf1, Mmus\Rnf168, Mmus\Bfar" "Hsap\RNF180, Hsap\LONRF1, Hsap\LONRF2, Hsap\BFAR, Hsap\RNF168, Hsap\LONRF3" "viable,fertile" DRSC10834 E 0.033188987 -0.536227494 2.209639196 -1.200422576 0.621476889 0.930578903 FBgn0262122 739b - http://flybase.org/reports/FBgn0262122 gene - - - 739b - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015578 betaTub60D::betaTub85D betaTub60D::betaTub85D http://flybase.org/reports/FBgn0015578 - engineered_fusion_gene - - - "beta2beta3, betaTub60D::betaTub85D" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile axoneme FBgn0259999 CG41072 - http://flybase.org/reports/FBgn0259999 protein_coding_gene - - - "anon-38C.23, CG41072, 38C.23" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060307 l(3)S148307 lethal (3) S148307 http://flybase.org/reports/FBgn0060307 gene - - - "1483/07, l(3)S148307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0263113 Cc2d2a Coiled-coil and C2 domain containing 2A http://flybase.org/reports/FBgn0263113 protein_coding_gene - cilium assembly ; GO:0060271 | inferred from sequence model MKS complex ; GO:0036038 | inferred from sequence or structural similarity with MGI:MGI:1924487 ciliary transition zone ; GO:0035869 | inferred from direct assay "CG18432, CG18631, cc2d2a, Cc2d2a, CC2D2A, CG43370" "IPR028928:CC2D2A, N-terminal, C2 domain, IPR000008:C2 domain" CG43370 11-Aug-17 DroID_v2017_08 Drer\cc2d2a - Cele\mks-6 Xtro\cc2d2a Mmus\Cc2d2a "Hsap\C10orf131, Hsap\CC2D2A, Hsap\CC2D2B" FBgn0038516 P5cr-2 Pyrroline-5-carboxylate reductase-like 2 http://flybase.org/reports/FBgn0038516 protein_coding_gene pyrroline-5-carboxylate reductase activity ; GO:0004735 | inferred from electronic annotation with InterPro:IPR000304 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000304, InterPro:IPR008927 proline biosynthetic process ; GO:0006561 | inferred from electronic annotation with InterPro:IPR000304" - "CT18319, CG5840, P5cr-2" "IPR000304:Pyrroline-5-carboxylate reductase, IPR029036:Pyrroline-5-carboxylate reductase, dimerisation domain, IPR028939:Pyrroline-5-carboxylate reductase, catalytic, N-terminal, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR016040:NAD(P)-binding domain" CG5840 11-Aug-17 DroID_v2017_08 "Drer\pycr1a, Drer\pycrl, Drer\pycr1b, Drer\pycr1" Scer\PRO3 "Cele\F55G1.9, Cele\M153.1" "Xtro\pycrl, Xtro\pycr1" "Mmus\Noxred1, Mmus\Pycr2, Mmus\Pycr1, Mmus\Pycrl" "Hsap\PYCRL, Hsap\PYCR1, Hsap\PYCR2, Hsap\NOXRED1, Hsap\LEFTY1" viable FBgn0000742 fs(1)A180 female sterile (1) A180 http://flybase.org/reports/FBgn0000742 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)180, fs(1)A180" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile soma-dependent,recessive" egg FBgn0034745 CG4329 - http://flybase.org/reports/FBgn0034745 protein_coding_gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - "anon-WO0140519.244, CG4329" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG4329 11-Aug-17 DroID_v2017_08 "Drer\cfap57, Drer\eml2, Drer\si:dkey-1f12.3" - - Xtro\cfap57 "Mmus\Eml5, Mmus\Cfap52, Mmus\Mtus1, Mmus\Eml4, Mmus\Cfap57, Mmus\Eml1" "Hsap\EML2, Hsap\CFAP57, Hsap\EML6, Hsap\MTUS1, Hsap\CFAP52, Hsap\EML5, Hsap\EML1" "auditory perception defective,neurophysiology defective" FBgn0032055 CG13091 - http://flybase.org/reports/FBgn0032055 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - "CT32316, CG13091" "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG13091 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97m3.1, Drer\far1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR1, Hsap\FAR2" viable FBgn0033408 CG8800 - http://flybase.org/reports/FBgn0033408 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q9XHH2 CG8800 "IPR025875:Leucine rich repeat 4, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG8800 11-Aug-17 DroID_v2017_08 "Drer\vasna, Drer\lrrcc1, Drer\si:ch211-103e16.5, Drer\lrriq1, Drer\dnal1, Drer\lrguk, Drer\cep97, Drer\si:dkey-267j14.7, Drer\lrrc6, Drer\ppp1r7, Drer\lrrc23, Drer\lrrc9, Drer\drc3, Drer\lrrc61, Drer\vasnb" "Scer\SDS22, Scer\NUD1" - "Xtro\drc3, Xtro\lrrcc1, Xtro\lrrc6, Xtro\lrrc49, Xtro\dnal1, Xtro\cep97, Xtro\ppp1r7, Xtro\lrrc23, Xtro\lrrc9, Xtro\lrrc56" "Mmus\Lrguk, Mmus\Lrrc23, Mmus\Lrrc9, Mmus\Lrriq3, Mmus\Lrrc61, Mmus\Ppp1r7, Mmus\Lrriq1, Mmus\Lrrc48, Mmus\Lrrc6, Mmus\Lrrc56, Mmus\Cep97, Mmus\Lrrcc1, Mmus\Lrrc43, Mmus\Dnal1, Mmus\Lrrc49, Mmus\Lrrc46" "Hsap\LRGUK, Hsap\LRRCC1, Hsap\LRRC56, Hsap\LRRC46, Hsap\LRRC43, Hsap\LRRC61, Hsap\DNAL1, Hsap\CEP97, Hsap\LRRIQ3, Hsap\DRC3, Hsap\LRRC49, Hsap\PPP1R7, Hsap\LRRC6, Hsap\LRRIQ1, Hsap\LRRC23" viable FBgn0014168 fs(1)5Da fs(1)5Da http://flybase.org/reports/FBgn0014168 - gene - - - fs(1)5Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "ovariole,germarium,follicle cell" FBgn0267438 CR45788 - http://flybase.org/reports/FBgn0267438 non_protein_coding_gene - - - CR45788 - CR45788 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034542 Fem-1 Fem-1 http://flybase.org/reports/FBgn0034542 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with UniProtKB:Q9UK73 regulation of ubiquitin-protein transferase activity ; GO:0051438 | inferred from sequence or structural similarity with UniProtKB:Q9UK73 cellular_component ; GO:0005575 | no biological data available "CG9025, Fem-1, dFEM-1" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG9025 11-Aug-17 DroID_v2017_08 "Drer\ankrd46b, Drer\fem1b" - Cele\fem-1 "Xtro\fem1b, Xtro\fem1c" "Mmus\Fem1c, Mmus\Fem1a, Mmus\Fem1b, Mmus\Ankrd46, Mmus\4931440F15Rik" "Hsap\LONRF2, Hsap\ANKRD46, Hsap\FEM1C, Hsap\FEM1B, Hsap\FEM1A" viable FBgn0036926 CG7646 - http://flybase.org/reports/FBgn0036926 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" - - "anon-EST:Posey160, BcDNA:RH69723, CG7646" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG7646 11-Aug-17 DroID_v2017_08 "Drer\kcnip1a, Drer\si:ch211-145b13.5, Drer\vsnl1a, Drer\usp32, Drer\kcnip3b, Drer\kcnip4, Drer\ncs1a, Drer\kcnip2, Drer\si:ch211-245j22.3, Drer\guca1c, Drer\guca1b, Drer\ncs1b, Drer\rcvrn3, Drer\guca1g, Drer\efcab1, Drer\ncalda, Drer\hpcal1, Drer\rcvrnb, Drer\rcvrna, Drer\ncaldb, Drer\rcvrn2, Drer\si:ch211-103a14.5, Drer\guca1d, Drer\hpcal4, Drer\vsnl1b, Drer\guca1a, Drer\guca1e, Drer\hpca, Drer\kcnip1b" Scer\FRQ1 "Cele\ncs-3, Cele\ncs-2, Cele\ncs-1" "Xtro\hpca, Xtro\rcvrn.2, Xtro\kcnip2, Xtro\vsnl1, Xtro\efcab1, Xtro\ncs1, Xtro\hpcal1, Xtro\ncald, Xtro\kcnip4, Xtro\guca1a, Xtro\guca1c, Xtro\kcnip1, Xtro\kcnip3, Xtro\guca1b" "Mmus\Hpcal4, Mmus\Kcnip4, Mmus\Efcab1, Mmus\1700109H08Rik, Mmus\Vsnl1, Mmus\Ncs1, Mmus\Usp32, Mmus\Guca1a, Mmus\Hpcal1, Mmus\Hpca, Mmus\Guca1b, Mmus\Kcnip1, Mmus\Rcvrn, Mmus\Kcnip2, Mmus\Kcnip3, Mmus\Ncald" "Hsap\VSNL1, Hsap\KCNIP4, Hsap\HPCAL1, Hsap\KCNIP3, Hsap\GUCA1A, Hsap\HPCAL4, Hsap\USP32, Hsap\NCALD, Hsap\RCVRN, Hsap\HPCA, Hsap\GUCA1B, Hsap\KCNIP2, Hsap\KCNIP1, Hsap\EFCAB1, Hsap\GUCA1C, Hsap\NCS1" viable FBgn0069133 mde mesoderm-excluded http://flybase.org/reports/FBgn0069133 gene - - - mde - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065430 l(2)SH1496 lethal (2) SH1496 http://flybase.org/reports/FBgn0065430 gene - - - "l(2)SH1496, l(2)SH2 1496" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033925 CG8617 - http://flybase.org/reports/FBgn0033925 protein_coding_gene - - prefoldin complex ; GO:0016272 | colocalizes_with inferred from direct assay CG8617 - CG8617 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041626 Or19a Odorant receptor 19a http://flybase.org/reports/FBgn0041626 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from direct assay "19a, CG18859, DOR37, 19A.1, Or19a, Or19a-1" "IPR004117:Olfactory receptor, insect" CG18859 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20684 K 0.507266739 0.01447537 -0.259516503 0.568276721 -5.364766097 -2.856164402 FBgn0260758 CG42556 - http://flybase.org/reports/FBgn0260758 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cobalamin metabolic process ; GO:0009235 | inferred from electronic annotation with InterPro:IPR019362 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15133, CG42556" IPR019362:Methylmalonic aciduria and homocystinuria type D protein CG42556 11-Aug-17 DroID_v2017_08 "Drer\mmadhc, Drer\si:ch211-233a24.2, Drer\zgc:92335" Scer\CSF1 Cele\Y76A2B.5 "Xtro\kiaa1109, Xtro\mmadhc" "Mmus\4932438A13Rik, Mmus\Mmadhc" "Hsap\MMADHC, Hsap\KIAA1109" viable FBgn0085730 CG42228 - http://flybase.org/reports/FBgn0085730 protein_coding_gene - - - CG42228 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043882 mdg3\ORF mdg3 element ORF http://flybase.org/reports/FBgn0043882 transposable_element_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR012337" DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "mdg3NC, mdg3\ORF" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR003034:SAP domain, IPR012337:Ribonuclease H-like domain, IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037561 CG9630 - http://flybase.org/reports/FBgn0037561 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000001894 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "DmRH16, cg9630, CG9630" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR025313:Domain of unknown function DUF4217, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9630 11-Aug-17 DroID_v2017_08 Drer\ddx55 Scer\SPB4 Cele\ZK512.2 Xtro\ddx55 Mmus\Ddx55 Hsap\DDX55 "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0000955 fs(2)E2 female sterile (2) E2 http://flybase.org/reports/FBgn0000955 - gene - - - "fs2.2, fs(2)E2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" egg FBgn0023196 LPA-AT Lysophosphatidate Acyltransferase http://flybase.org/reports/FBgn0023196 - gene - - - LPA-AT - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027137 l(3)88Ae lethal (3) 88Ae http://flybase.org/reports/FBgn0027137 - gene - - - l(3)88Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266638 CR45145 - http://flybase.org/reports/FBgn0266638 non_protein_coding_gene - - - CR45145 - CR45145 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052213 CG32213 - http://flybase.org/reports/FBgn0052213 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32213 - CG32213 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027188 l(2)60A-D lethal (2) 60A-D http://flybase.org/reports/FBgn0027188 - gene - - - l(2)60A-D - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025930 hip66 hb-interacting protein 66 http://flybase.org/reports/FBgn0025930 - gene - - - hip66 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043876 micropia\polyprotein micropia element polyprotein http://flybase.org/reports/FBgn0043876 transposable_element_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - micropia\polyprotein "IPR012337:Ribonuclease H-like domain, IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086856 CG11555 - http://flybase.org/reports/FBgn0086856 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG11555, anon-21Ca" - CG11555 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,trichogen cell" FBgn0015240 Hr96 Hormone receptor-like in 96 http://flybase.org/reports/FBgn0015240 - protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement" steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype regulation of glycogen metabolic process ; GO:0070873 | inferred from mutant phenotype cholesterol homeostasis ; GO:0042632 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001628 "DHR96, NR1J1, Dhr96, CG11783, Hr96, HR96, dHR96" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR013088:Zinc finger, NHR/GATA-type" CG11783 11-Aug-17 DroID_v2017_08 "Drer\esr1, Drer\esrrga, Drer\rargb, Drer\nr2f1b, Drer\nr1d4b, Drer\nr0b2b, Drer\nr1d1, Drer\nr1h4, Drer\esrra, Drer\esrrd, Drer\pparaa, Drer\nr2f1a, Drer\thrab, Drer\pparda, Drer\nr2e1, Drer\rxrga, Drer\ar, Drer\rxraa, Drer\nr2f6a, Drer\esr2b, Drer\nr1i2, Drer\nr1d2b, Drer\raraa, Drer\ppardb, Drer\rxrba, Drer\nr2f6b, Drer\nr2c2, Drer\esr2a, Drer\nr1d4a, Drer\nr1h5, Drer\pgr, Drer\nr2c1, Drer\nr6a1b, Drer\pparab, Drer\pparg, Drer\nr2e3, Drer\vdra, Drer\nr3c1, Drer\nr0b2a, Drer\nr1d2a, Drer\rxrab, Drer\rxrbb, Drer\nr2f2, Drer\rarab, Drer\vdrb, Drer\nr0b1, Drer\nr2f5, Drer\nr5a1a" - "Cele\nhr-48, Cele\nhr-8, Cele\daf-12" "Xtro\esrrg, Xtro\esr1, Xtro\ar, Xtro\nr3c2, Xtro\nr2c2, Xtro\nr2f1, Xtro\esrra, Xtro\nr2e1, Xtro\nr1h2, Xtro\rara, Xtro\nr1h5, Xtro\rxrg, Xtro\rarg, Xtro\pparg, Xtro\esrrb, Xtro\nr2f5, Xtro\ppara, Xtro\nr0b1, Xtro\thrb, Xtro\rxrb, Xtro\rxra, Xtro\ppard, Xtro\pgr, Xtro\nr0b2, Xtro\nr2f2, Xtro\esr2, Xtro\nr2e3, Xtro\nr2f6, Xtro\nr2c1, Xtro\vdr, Xtro\nr3c1, Xtro\nr1i2, Xtro\rarb, Xtro\esrrgr, Xtro\nr6a1" "Mmus\Ar, Mmus\Vdr, Mmus\Ppara, Mmus\Nr3c1, Mmus\Pparg, Mmus\Nr1d1, Mmus\Nr6a1, Mmus\Nr2c2, Mmus\Rarb, Mmus\Pgr, Mmus\Thra, Mmus\Ppard, Mmus\Nr2e1, Mmus\Rarg, Mmus\Rxra, Mmus\Nr1h2, Mmus\Nr2f6, Mmus\Nr1d2, Mmus\Esr2, Mmus\Esrrg, Mmus\Nr2f2, Mmus\Nr1h5, Mmus\Rxrb, Mmus\Nr2f1, Mmus\Esrra, Mmus\Esrrb, Mmus\Nr2e3, Mmus\Nr1i2, Mmus\Rorb, Mmus\Nr1h4, Mmus\Nr3c2, Mmus\Nr2c1, Mmus\Rara, Mmus\Rxrg, Mmus\Nr1h3, Mmus\Nr0b2, Mmus\Esr1, Mmus\Nr0b1, Mmus\Thrb, Mmus\Nr1i3" "Hsap\RXRA, Hsap\NR1H4, Hsap\NR3C2, Hsap\NR1I3, Hsap\NR0B2, Hsap\PPARG, Hsap\NR0B1, Hsap\NR2F6, Hsap\NR6A1, Hsap\NR1D2, Hsap\NR2C2, Hsap\ESR1, Hsap\VDR, Hsap\RXRG, Hsap\RORB, Hsap\AR, Hsap\NR1D1, Hsap\RARA, Hsap\PPARA, Hsap\ESRRG, Hsap\NR2F1, Hsap\ESRRA, Hsap\NR1H3, Hsap\THRB, Hsap\NR1H2, Hsap\PGR, Hsap\RXRB, Hsap\RARB, Hsap\NR2E1, Hsap\THRA, Hsap\NR2F2, Hsap\NR1I2, Hsap\RARG, Hsap\ESR2, Hsap\NR2C1, Hsap\NR3C1, Hsap\PPARD, Hsap\ESRRB" larval stage && prepupal stage "lethal,chemical resistant,starvation stress response defective,viable,fertile,chemical sensitive,decreased cell size" "adult fat body,lipid particle,adult midgut epithelium,lipid particle, with Hr961.3',lipid particle, with Hr961.5'" FBgn0015721 ktub king tubby http://flybase.org/reports/FBgn0015721 FBgn0034589 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000421275 protein localization to cilium ; GO:0061512 | inferred from mutant phenotype response to sucrose ; GO:0009744 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype glucose homeostasis ; GO:0042593 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay cilium ; GO:0005929 | inferred from direct assay "Tulp, D-tulp, Dtulp, 87D3S, ESTS:87D3S, TULP, CG9398, tulp, King-tubby, ktub, king-tubby, dTULP, dTulp" "IPR025659:Tubby C-terminal-like domain, IPR018066:Tubby, C-terminal, conserved site, IPR000007:Tubby, C-terminal" CG9398 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000000711, Drer\tub, Drer\tulp1a, Drer\si:dkey-220f10.4, Drer\LOC103908677, Drer\tulp1b" - Cele\tub-1 "Xtro\tulp2, Xtro\tub, Xtro\tulp1, Xtro\tulp3" "Mmus\Tub, Mmus\Tulp2, Mmus\Tulp3, Mmus\Tulp1" "Hsap\TUB, Hsap\TULP3, Hsap\TULP1, Hsap\TULP2" "neuroanatomy defective,conditional,viable,stress response defective,chemical resistant,large body" "outer photoreceptor cell,conditional,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6" FBgn0001304 Kf1 Kynurenine formamidase 1 http://flybase.org/reports/FBgn0001304 - gene arylformamidase activity ; GO:0004061 | inferred from direct assay - - Kf1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260954 CG42586 - http://flybase.org/reports/FBgn0260954 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42586 - CG42586 11-Aug-17 DroID_v2017_08 - - Cele\F16B4.7 - - - FBgn0014980 l(2)46Ca lethal (2) 46Ca http://flybase.org/reports/FBgn0014980 - gene - - - "I, l(2)46Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0086209 su(comp)3L-1 - http://flybase.org/reports/FBgn0086209 gene - - - su(comp)3L-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267616 CR45954 - http://flybase.org/reports/FBgn0267616 non_protein_coding_gene - - - CR45954 - CR45954 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032402 CG14945 - http://flybase.org/reports/FBgn0032402 protein_coding_gene glycosylphosphatidylinositol diacylglycerol-lyase activity ; GO:0047396 | inferred from electronic annotation with InterPro:IPR003633 phosphoric diester hydrolase activity ; GO:0008081 | inferred from electronic annotation with InterPro:IPR017946 glycerophospholipid metabolic process ; GO:0006650 | inferred from electronic annotation with InterPro:IPR003633 - "CG14945, cg14945" "IPR000909:Phosphatidylinositol-specific phospholipase C, X domain, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR003633:Phospholipase C, variant-surface-glycoprotein" CG14945 11-Aug-17 DroID_v2017_08 "Drer\LOC100151335, Drer\plcxd2, Drer\plcxd1, Drer\si:dkey-66a8.7, Drer\zgc:64065, Drer\plcxd3, Drer\zgc:112023" - Cele\F38E9.1 "Xtro\plcxd1, Xtro\plcxd3, Xtro\plcxd2" "Mmus\Plcxd3, Mmus\Plcxd2, Mmus\Plcxd1" "Hsap\PLCXD2, Hsap\PLCXD1, Hsap\PLCXD3" viable FBgn0065575 l(2)SH0954 lethal (2) SH0954 http://flybase.org/reports/FBgn0065575 gene - - - l(2)SH0954 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013452 fs(2)R2.503 fs(2)R2.503 http://flybase.org/reports/FBgn0013452 - gene - - - fs(2)R2.503 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0036341 Syx13 Syntaxin 13 http://flybase.org/reports/FBgn0036341 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with RGD:4892614 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNARE binding ; GO:0000149 | inferred from sequence or structural similarity with RGD:4892614 SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 protein binding ; GO:0005515 | inferred from physical interaction with Vps45 vesicle fusion ; GO:0006906 | inferred from sequence or structural similarity with RGD:4892614 vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 female meiotic division ; GO:0007143 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype vesicle docking ; GO:0048278 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with RGD:4892614 "ff16, ff16 (69D1-70A2), DmSyx13, Dm Syx13, l(3)01470, CG11278, Syx13, Syx, syx13, SYN13, Syx20" "IPR000727:Target SNARE coiled-coil homology domain, IPR006012:Syntaxin/epimorphin, conserved site, IPR010989:SNARE, IPR006011:Syntaxin, N-terminal domain" CG11278 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-208k15.1, Drer\stx7l, Drer\stx12l, Drer\stx17, Drer\stx12" "Scer\PEP12, Scer\TLG2, Scer\VAM3" "Cele\syx-17, Cele\syx-7" "Xtro\stx7, Xtro\tsnare1, Xtro\stx12" "Mmus\Stx12, Mmus\Stx17, Mmus\Stx7" "Hsap\STX17, Hsap\TSNARE1, Hsap\STX7, Hsap\STX12" "lethal,recessive,male sterile,female sterile,visible,meiotic cell cycle defective,mitotic cell cycle defective,viable" "polytene chromosome chromocenter,chaeta,meiotic cell cycle | male,meiotic cell cycle | female,meiosis & nuclear chromosome | male,meiotic anaphase I | male,meiotic metaphase II | male,meiotic telophase II | male,spermatozoon,onion stage spermatid,egg chamber,ovariole,nurse cell,karyosome,oocyte & spindle,oocyte,mitotic cell cycle,mitotic metaphase,mitotic cell cycle & spindle,mitotic cell cycle & nuclear chromosome" FBgn0266678 CR45168 - http://flybase.org/reports/FBgn0266678 non_protein_coding_gene - - - CR45168 - CR45168 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032315 CG14069 - http://flybase.org/reports/FBgn0032315 protein_coding_gene cytokine activity ; GO:0005125 | inferred from sequence or structural similarity with Gbp1 signal transduction ; GO:0007165 | inferred from sequence or structural similarity with Gbp1 cellular_component ; GO:0005575 | no biological data available CG14069 - CG14069 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0259754 ms(2)Fra-15 - http://flybase.org/reports/FBgn0259754 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - ms(2)Fra-15 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "Y chromosome loop,Nebenkern,spermatid,nucleus & spermatid,spermatozoon" FBgn0011565 boas beads on a string http://flybase.org/reports/FBgn0011565 - gene - - - boas - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" ovary FBgn0001358 l(1)1EFg lethal (1) 1EFg http://flybase.org/reports/FBgn0001358 - gene - - - "l(1)BA7, l(1)1EFg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010060 M(2)33d M(2)33d http://flybase.org/reports/FBgn0010060 - gene - - - M(2)33d - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011137 l(1)Q212 lethal (1) Q212 http://flybase.org/reports/FBgn0011137 FBgn0010210 gene - - - l(1)Q212 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065694 l(2)SH0639 lethal (2) SH0639 http://flybase.org/reports/FBgn0065694 gene - - - "l(2)SH0639, l(2)SH2 0639" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023027 l(2)CA8 lethal (2) CA8 http://flybase.org/reports/FBgn0023027 - gene - - - l(2)CA8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267316 CR45752 - http://flybase.org/reports/FBgn0267316 non_protein_coding_gene - - - CR45752 - CR45752 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013393 anon-64Ba anon-64Ba http://flybase.org/reports/FBgn0013393 - gene - - - anon-64Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265760 CR44567 - http://flybase.org/reports/FBgn0265760 non_protein_coding_gene - - - CR44567 - CR44567 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267950 CR46230 - http://flybase.org/reports/FBgn0267950 non_protein_coding_gene - - - "CR46230, lincRNA.497" - CR46230 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043027 l(2)42Ec lethal (2) 42Ec http://flybase.org/reports/FBgn0043027 gene - - - l(2)42Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005564 Shal Shaker cognate l http://flybase.org/reports/FBgn0005564 "FBgn0003385, FBgn0003394" protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | traceable author statement A-type (transient outward) potassium channel activity ; GO:0005250 | inferred from direct assay "protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR003968, InterPro:IPR003975, InterPro:IPR028325 chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | traceable author statement associative learning ; GO:0008306 | inferred from mutant phenotype" "voltage-gated potassium channel complex ; GO:0008076 | inferred from electronic annotation with InterPro:IPR003968, InterPro:IPR003975, InterPro:IPR028325 voltage-gated potassium channel complex ; GO:0008076 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity" "CG9262, shal, dShal, Shl, Sh-l, Shal, Kv4, DNK[[v]]4, K[[v]]4" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR003968:Potassium channel, voltage dependent, Kv, IPR003975:Potassium channel, voltage dependent, Kv4, IPR005821:Ion transport domain, IPR024587:Potassium channel, voltage dependent, Kv4, C-terminal, IPR028325:Voltage-gated potassium channel, IPR021645:Shal-type voltage-gated potassium channels, N-terminal" CG9262 11-Aug-17 DroID_v2017_08 "Drer\kcnd3, Drer\kcnd2, Drer\kcnd1" - Cele\shl-1 "Xtro\kcnd2, Xtro\kcnd3, Xtro\kcnd1" "Mmus\Kcnd3, Mmus\Kcnd1, Mmus\Kcnd2" "Hsap\KCND3, Hsap\KCND1, Hsap\KCND2" "viable,fertile,neurophysiology defective,locomotor behavior defective,grooming behavior defective,chemical conditional" "embryonic/larval neuron,motor neuron | embryonic stage" FBgn0005359 Su(w[a])B2 Suppressor of white-apricot B on 2 http://flybase.org/reports/FBgn0005359 - gene - - - Su(w[a])B2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0021779 l(3)95Ca lethal (3) 95Ca http://flybase.org/reports/FBgn0021779 - gene - - - l(3)95Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032026 CG7627 - http://flybase.org/reports/FBgn0032026 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 wound healing ; GO:0042060 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN002384094 "Dme_CG7627, CG7627" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG7627 11-Aug-17 DroID_v2017_08 "Drer\abcc9, Drer\abcc10, Drer\abcc5, Drer\abcc4, Drer\abcc2, Drer\abcc12, Drer\abcc3, Drer\cftr, Drer\abcc6b.2, Drer\abcc1, Drer\LOC100329706, Drer\abcc6a, Drer\abcc13, Drer\abcc8" "Scer\YKR104W, Scer\BPT1, Scer\YBT1, Scer\YCF1, Scer\VMR1, Scer\YOR1, Scer\NFT1" "Cele\mrp-3, Cele\mrp-1, Cele\mrp-4, Cele\mrp-8, Cele\mrp-7, Cele\mrp-5, Cele\mrp-2, Cele\mrp-6" "Xtro\abcc6, Xtro\abcc4, Xtro\abcc3, Xtro\abcc10, Xtro\cftr, Xtro\abcc1" "Mmus\Abcc5, Mmus\Abcc2, Mmus\Abcc4, Mmus\Abcc10, Mmus\Abcc8, Mmus\Abcc3, Mmus\Abcc6, Mmus\Abcc12, Mmus\Abcc1, Mmus\Abcc9, Mmus\Cftr" "Hsap\ABCC10, Hsap\ABCC1, Hsap\CFTR, Hsap\ABCC2, Hsap\ABCC6, Hsap\ABCC12, Hsap\ABCC9, Hsap\ABCC5, Hsap\ABCC4, Hsap\ABCC11, Hsap\ABCC8, Hsap\ABCC3" "viable,fertile" FBgn0030364 CG15735 - http://flybase.org/reports/FBgn0030364 protein_coding_gene molecular_function ; GO:0003674 | no biological data available RNA metabolic process ; GO:0016070 | inferred from sequence or structural similarity with SGD:S000001163 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000001163 "BcDNA:LD05893, CG15735" IPR019181:Anticodon-binding domain CG15735 11-Aug-17 DroID_v2017_08 "Drer\lsm12b, Drer\lsm12a" Scer\LSM12 Cele\M142.5 Xtro\lsm12 Mmus\Lsm12 Hsap\LSM12 viable FBgn0283426 acal acal http://flybase.org/reports/FBgn0283426 non_protein_coding_gene - negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype inferred from genetic interaction with bsk inferred from genetic interaction with hep inferred from genetic interaction with Cka dorsal closure ; GO:0007391 | inferred from mutant phenotype - "acal, CR46278" - CR46278 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039341 CG5112 - http://flybase.org/reports/FBgn0039341 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay CG5112 "IPR023631:Amidase signature domain, IPR020556:Amidase, conserved site" CG5112 11-Aug-17 DroID_v2017_08 "Drer\faah2a, Drer\faah2b, Drer\faah" Scer\AMD2 "Cele\faah-3, Cele\Y53F4B.18, Cele\faah-2, Cele\faah-6, Cele\faah-5, Cele\faah-1" "Xtro\faah2, Xtro\faah.1, Xtro\faah.3, Xtro\faah.2" Mmus\Faah "Hsap\FAAH2, Hsap\FAAH" "viable,fertile" FBgn0050290 Ppcdc Phosphopantothenoylcysteine decarboxylase http://flybase.org/reports/FBgn0050290 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR003382 phosphopantothenoylcysteine decarboxylase activity ; GO:0004633 | inferred from sequence alignment with AGI_LocusCode:AT3G18030 coenzyme A biosynthetic process ; GO:0015937 | inferred from sequence alignment with SGD:S000001571 - "BcDNA:LD37882, Dromel_CG30290_FBtr0071672_cx9c_mORF, Ppcdc, PPCDC, CG30290, dPPCDC" IPR003382:Flavoprotein CG30290 11-Aug-17 DroID_v2017_08 Drer\ppcdc "Scer\CAB3, Scer\VHS3, Scer\SIS2" Cele\F25H9.6 Xtro\ppcdc Mmus\Ppcdc Hsap\PPCDC "viable,visible" trichogen cell DRSC03886 I 0.083839311 3.038274453 -0.220046697 0.931310059 -0.325521075 0.336648198 FBgn0001365 l(1)1Fd lethal (1) 1Fd http://flybase.org/reports/FBgn0001365 - gene - - - l(1)1Fd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,maternal effect,some die during pupal stage,lethal,recessive,germline clone" "segment,germline clone" FBgn0261445 sgl sugarless http://flybase.org/reports/FBgn0261445 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR001732, InterPro:IPR014026, InterPro:IPR014027 UDP-glucose 6-dehydrogenase activity ; GO:0003979 | inferred from mutant phenotype UDP-glucose 6-dehydrogenase activity ; GO:0003979 | traceable author statement" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001732, InterPro:IPR008927, InterPro:IPR014026, InterPro:IPR014027, InterPro:IPR017476 mesoderm migration involved in gastrulation ; GO:0007509 | traceable author statement mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q09147 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype heart development ; GO:0007507 | non-traceable author statement primary branching, open tracheal system ; GO:0007428 | traceable author statement smoothened signaling pathway ; GO:0007224 | traceable author statement segment polarity determination ; GO:0007367 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement chondroitin sulfate biosynthetic process ; GO:0030206 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q07407 olfactory behavior ; GO:0042048 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | non-traceable author statement glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | traceable author statement heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | traceable author statement heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | non-traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype chondroitin sulfate biosynthetic process ; GO:0030206 | traceable author statement" - "sgl, kiwi, ska, CG10072, UDPGDH, UDP-GlcDH, 8310, sl, XIII, l(3)SG9, l(3)65CEd, l(3)10503, l(3)08310, l(3)05007, BG01214, Sgl" "IPR028356:UDP-glucose 6-dehydrogenase, eukaryotic type, IPR001732:UDP-glucose/GDP-mannose dehydrogenase, N-terminal, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR014026:UDP-glucose/GDP-mannose dehydrogenase, dimerisation, IPR014027:UDP-glucose/GDP-mannose dehydrogenase, C-terminal, IPR016040:NAD(P)-binding domain, IPR017476:UDP-glucose/GDP-mannose dehydrogenase" CG10072 11-Aug-17 DroID_v2017_08 Drer\ugdh - Cele\sqv-4 "Xtro\ugdh.2, Xtro\ugdh" Mmus\Ugdh Hsap\UGDH " embryonic stage | stage 17 , embryonic stage | stage <4 , larval stage | third instar , embryonic stage | stage >9 , embryonic stage | stage 16-17 , embryonic stage | early , embryonic stage | stage 13 , embryonic stage , embryonic stage | stage 9-14 , embryonic stage | extended germ band " " embryonic/larval pharynx

,

ubiquitous , imaginal disc

, cephalic furrow | surrounding

, embryonic/larval hindgut

, morphogenetic furrow

, embryonic/larval proventriculus

, embryonic/larval midgut

, amnioserosa | presumptive

, mesoderm

" FBgn0085677 CG41538 - http://flybase.org/reports/FBgn0085677 protein_coding_gene - - - CG41538 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002919 NaCP37B Na channel protein 37B http://flybase.net/reports/FBgn0002919.html gene 0005248=voltage-gated sodium channel activity 0035725=sodium ion transmembrane transport 0005886=plasma membrane DIC37 "IPR028820=Sodium channel protein 60E, IPR005821=Ion transport domain" 11-Aug-17 DroID_v2017_08 FBgn0022335 f36 f36 http://flybase.org/reports/FBgn0022335 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available f36 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" "spermatocyte,primary spermatocyte cyst,germarium,ovary,testis,ganglion" FBgn0024599 sine sine http://flybase.org/reports/FBgn0024599 - gene molecular_function ; GO:0003674 | no biological data available Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sine - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "Bolwig nerve,Bolwig organ" FBgn0000919 fs(1)ne5 female sterile (1) no eggs 5 http://flybase.org/reports/FBgn0000919 - gene - - - "ne5, fs(1)ne[5], fs(1)ne5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "dorsal appendage,chorion,stage S10A oocyte,stage S10B oocyte" FBgn0260713 CG42544 - http://flybase.org/reports/FBgn0260713 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42544, HCD12266" - CG42544 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029709 CHOp24 CHOp24 http://flybase.org/reports/FBgn0029709 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence model positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype positive regulation of Wnt protein secretion ; GO:0061357 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred from sequence model wing disc development ; GO:0035220 | inferred from mutant phenotype positive regulation of protein exit from endoplasmic reticulum ; GO:0070863 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from mutant phenotype regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype reproduction ; GO:0000003 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from sequence model endomembrane system ; GO:0012505 | inferred from direct assay "CG3564, CHOp24, Emp24, p24, emp24, p24/p24beta1" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG3564 11-Aug-17 DroID_v2017_08 Drer\tmed2 "Scer\ERP4, Scer\ERP2, Scer\EMP24, Scer\ERP3" "Cele\C26C6.9, Cele\sel-9, Cele\Y73B6BL.36" Xtro\tmed2 "Mmus\Tmed2, Mmus\Gm10698" Hsap\TMED2 "viable,visible,lethal,female semi-sterile" "chaeta,supernumerary,wing margin,somatic clone" FBgn0264897 CG44088 - http://flybase.org/reports/FBgn0264897 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44088 - CG44088 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021823 l(2)k16204 lethal (2) k16204 http://flybase.org/reports/FBgn0021823 - gene - - - l(2)k16204 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261791 SNRPG Small nuclear ribonucleoprotein G http://flybase.org/reports/FBgn0261791 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:11163 RNA binding ; GO:0003723 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000058283 "spliceosomal snRNP assembly ; GO:0000387 | inferred from electronic annotation with InterPro:IPR034098 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000058285" SMN-Sm protein complex ; GO:0034719 | inferred from biological aspect of ancestor with PANTHER:PTN000058285 P granule ; GO:0043186 | inferred from biological aspect of ancestor with PANTHER:PTN000058285 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000002965 U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000058285 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000058284 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000058285 U4 snRNP ; GO:0005687 | inferred from biological aspect of ancestor with PANTHER:PTN000058285 U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000058285 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000002965 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000058284 spliceosomal tri-snRNP complex ; GO:0097526 | inferred from biological aspect of ancestor with PANTHER:PTN000058285 "CG9742, BcDNA:RH35475, BcDNA:RE61341, HD10913, G, snRNPG, dG, G-Sm, SNRPG, SmG" "IPR034098:Small nuclear ribonucleoprotein G, IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain" CG9742 11-Aug-17 DroID_v2017_08 "Drer\lsm7, Drer\snrpg" "Scer\SMX2, Scer\LSM5" Cele\snr-7 "Xtro\lsm7, Xtro\snrpg" "Mmus\Snrpg, Mmus\Lsm7" "Hsap\LSM7, Hsap\SNRPG, Hsap\LSM5" FBgn0011736 wad waddell http://flybase.org/reports/FBgn0011736 - gene - - - "wdel, wad" - - 11-Aug-17 DroID_v2017_08 - - - - - - cleavage stage embryo FBgn0002977 obl oblique wings http://flybase.org/reports/FBgn0002977 - gene - - - obl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,good,male,male fertile,female,reduced,female fertile,female semi-sterile,body color defective" wing FBgn0034326 CG18540 - http://flybase.org/reports/FBgn0034326 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18540 IPR010512:Protein of unknown function DUF1091 CG18540 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265824 CR44613 - http://flybase.org/reports/FBgn0265824 non_protein_coding_gene - - - "CR44613, lincRNA.64" - CR44613 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260339 GSd434 - http://flybase.org/reports/FBgn0260339 gene - - - GSd434 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001039 fs(3)H23 female sterile (3) H23 http://flybase.org/reports/FBgn0001039 - gene - - - fs(3)H23 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile egg chamber FBgn0036488 CG6878 - http://flybase.org/reports/FBgn0036488 protein_coding_gene - regulation of mitophagy ; GO:1903146 | inferred from genetic interaction with park - "CG6878, Romo1" IPR018450:Romo1/Mgr2 CG6878 11-Aug-17 DroID_v2017_08 Drer\romo1 Scer\MGR2 "Cele\rmo-1, Cele\Y94A7B.11" Xtro\romo1 Mmus\Romo1 Hsap\ROMO1 viable FBgn0036757 Ir75a Ionotropic receptor 75a http://flybase.org/reports/FBgn0036757 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 extracellular ligand-gated ion channel activity ; GO:0005230 | contributes_to inferred from direct assay olfactory receptor activity ; GO:0004984 | contributes_to inferred from direct assay ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern sensory perception of sound ; GO:0007605 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay sensory dendrite ; GO:0071683 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay "Ir75a, IR75a, CG14585, DmelIR75a, IR75abc" IPR001320:Ionotropic glutamate receptor CG14585 11-Aug-17 DroID_v2017_08 "Drer\LOC100537813, Drer\LOC100334689, Drer\grid1a, Drer\grid1b" - Cele\W02A2.5 Xtro\grik5 "Mmus\Grid1, Mmus\Grik4" "Hsap\GRID2, Hsap\GRID1" "auditory perception defective,viable" FBgn0034789 PIP5K59B Phosphatidylinositol 4-phosphate 5-kinase at 59B http://flybase.org/reports/FBgn0034789 protein_coding_gene phosphatidylinositol phosphate kinase activity ; GO:0016307 | inferred from electronic annotation with InterPro:IPR002498 1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308 | non-traceable author statement "cellular response to light stimulus ; GO:0071482 | inferred from mutant phenotype positive regulation of phosphatidylinositol biosynthetic process ; GO:0010513 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype phosphorylation ; GO:0016310 | non-traceable author statement" rhabdomere microvillus membrane ; GO:0035997 | inferred from direct assay "CG3682, PIP5K 59B, CG17281, PIP5K59B, PI4P5K, dPIP5K" "IPR002498:Phosphatidylinositol-4-phosphate 5-kinase, core, IPR023610:Phosphatidylinositol-4-phosphate 5-kinase, IPR027484:Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain, IPR027483:Phosphatidylinositol-4-phosphate 5-kinase, C-terminal" CG3682 11-Aug-17 DroID_v2017_08 "Drer\pip5k1ca, Drer\si:ch211-243a15.1, Drer\psmd4a, Drer\pip5kl1, Drer\pip5k1aa, Drer\pip5k1ba, Drer\pip4k2ab, Drer\pip5k1bb, Drer\pip4k2aa, Drer\pip4k2cb, Drer\pip4k2ca, Drer\pip5k1ab" Scer\MSS4 "Cele\ppk-1, Cele\ppk-2" "Xtro\pip4k2c, Xtro\pip5k1a, Xtro\psmd4, Xtro\pip4k2a, Xtro\pip5k1b, Xtro\pip5kl1, Xtro\pip5k1c" "Mmus\Pip5k1b, Mmus\Pip4k2a, Mmus\Pip5kl1, Mmus\Pip5k1a, Mmus\Psmd4, Mmus\Pip4k2c, Mmus\Pip5k1c, Mmus\Pip4k2b" "Hsap\PIP4K2A, Hsap\PIP4K2B, Hsap\PSMD4, Hsap\PIP5KL1, Hsap\PIP5K1C, Hsap\PIP5K1B, Hsap\PIP5K1A, Hsap\PIP4K2C" viable embryonic/larval neuromuscular junction | third instar larval stage FBgn0085522 CG40818 - http://flybase.org/reports/FBgn0085522 protein_coding_gene - - - CG40818 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019762 l(1)71B lethal (1) 71B http://flybase.org/reports/FBgn0019762 - gene - - - l(1)71B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050358 CG30358 - http://flybase.org/reports/FBgn0050358 protein_coding_gene - - - CG30358 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031332 CG5556 - http://flybase.org/reports/FBgn0031332 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 CG5556 "IPR023198:Phosphoglycolate phosphatase, domain 2, IPR006439:HAD hydrolase, subfamily IA, IPR023214:HAD-like domain" CG5556 11-Aug-17 DroID_v2017_08 Drer\pudp "Scer\DOG1, Scer\DOG2, Scer\GPP1, Scer\YKL033W-A, Scer\GPP2" Cele\R151.10 Xtro\pudp Mmus\Hdhd1a Hsap\PUDP FBgn0042185 MCU Mitochondrial calcium uniporter http://flybase.org/reports/FBgn0042185 protein_coding_gene - medium-term memory ; GO:0072375 | inferred from mutant phenotype calcium ion transmembrane import into mitochondrion ; GO:0036444 | inferred from mutant phenotype anesthesia-resistant memory ; GO:0007615 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "CG8352, dMCU1, MCU, CG18769" "IPR006769:Coiled-coil domain containing protein 109, C-terminal" CG18769 11-Aug-17 DroID_v2017_08 Drer\mcu - Cele\mcu-1 "Xtro\mcu, Xtro\LOC101732332, Xtro\ccdc109b" "Mmus\Ccdc109b, Mmus\Mcu" "Hsap\MCUB, Hsap\MCU" "viable,fertile" FBgn0266929 CR45380 - http://flybase.org/reports/FBgn0266929 non_protein_coding_gene - - - CR45380 - CR45380 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016860 l(1)N8 lethal (1) N8 http://flybase.org/reports/FBgn0016860 - gene - - - "l(1)N8, N8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001717 l(1)ESHS38 lethal (1) ESHS38 http://flybase.org/reports/FBgn0001717 - gene - - - l(1)ESHS38 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022169 l(2)k05448 lethal (2) k05448 http://flybase.org/reports/FBgn0022169 - gene - - - l(2)k05448 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015622 Cnx99A Calnexin 99A http://flybase.org/reports/FBgn0015622 FBgn0039660 protein_coding_gene "unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001580 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001580, InterPro:IPR009033, InterPro:IPR018124" protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001580 regulation of calcium ion transport into cytosol ; GO:0010522 | inferred from mutant phenotype retina homeostasis ; GO:0001895 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity perinuclear endoplasmic reticulum ; GO:0097038 | inferred from direct assay "Cnx99A, CG11958, Cnx, cnx, Cnx99a" "IPR001580:Calreticulin/calnexin, IPR009033:Calreticulin/calnexin, P domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR018124:Calreticulin/calnexin, conserved site" CG11958 11-Aug-17 DroID_v2017_08 "Drer\calr, Drer\clgn, Drer\canx, Drer\si:ch211-274f20.2" Scer\CNE1 "Cele\cnx-1, Cele\crt-1" "Xtro\canx, Xtro\calr" "Mmus\Canx, Mmus\Calr, Mmus\Clgn" "Hsap\CLGN, Hsap\CANX, Hsap\CALR" embryonic stage " embryonic central nervous system

, peripheral nervous system

" "viable,neurophysiology defective,lethal,visible,partially lethal - majority die,some die during pupal stage" "retina,conditional,rhabdomere of eye photoreceptor cell,endoplasmic reticulum,Golgi apparatus,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,medial longitudinal fascicle,intermediate longitudinal fascicle,ventral nerve cord commissure,ventral nerve cord,trichogen cell,mesothoracic tergum" FBgn0263324 CR43405 - http://flybase.org/reports/FBgn0263324 non_protein_coding_gene - - - "CG43405, CR43405" - CR43405 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086201 S(ls)1 - http://flybase.org/reports/FBgn0086201 gene - - - S(ls)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016650 Lgr1 Leucine-rich repeat-containing G protein-coupled receptor 1 http://flybase.org/reports/FBgn0016650 - protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor activity ; GO:0004930 | inferred from direct assay protein-hormone receptor activity ; GO:0016500 | inferred from sequence or structural similarity G-protein coupled peptide receptor activity ; GO:0008528 | inferred from biological aspect of ancestor with PANTHER:PTN001224574 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model protein-hormone receptor activity ; GO:0016500 | inferred from direct assay hormone binding ; GO:0042562 | inferred from physical interaction with Gpb5, Gpa2" activation of adenylate cyclase activity ; GO:0007190 | inferred from biological aspect of ancestor with PANTHER:PTN001224574 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model cAMP-mediated signaling ; GO:0019933 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity hormone-mediated signaling pathway ; GO:0009755 | inferred from direct assay adenylate cyclase-activating G-protein coupled receptor signaling pathway ; GO:0007189 | inferred from biological aspect of ancestor with PANTHER:PTN001224574 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "Lgr1, DLGR1, Fsh/CG7665, DLGR-1, TSH, FSH, LH/CG receptor, FSH-TSH, CG7665, Fsh, RH44949p, dLGR1, LGR1" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR002131:Glycoprotein hormone receptor family, IPR017452:GPCR, rhodopsin-like, 7TM, IPR032675:Leucine-rich repeat domain, L domain-like, IPR034298:TSH/LHCG/FSH receptor, IPR001611:Leucine-rich repeat" CG7665 11-Aug-17 DroID_v2017_08 "Drer\fshr, Drer\tshr, Drer\rxfp2l, Drer\rxfp2a, Drer\lgr4, Drer\rxfp1, Drer\rxfp2b, Drer\lhcgr" - "Cele\lron-14, Cele\fshr-1" "Xtro\rxfp2, Xtro\fshr, Xtro\rxfp1, Xtro\tshr, Xtro\lhcgr" "Mmus\Lgr6, Mmus\Lgr5, Mmus\Lgr4, Mmus\Tshr, Mmus\Fshr, Mmus\Rxfp1, Mmus\Lhcgr, Mmus\Rxfp2" "Hsap\TSHR, Hsap\RXFP2, Hsap\LHCGR, Hsap\LGR4, Hsap\LGR5, Hsap\RXFP1, Hsap\LGR6, Hsap\FSHR" "viable,visible" mesothoracic tergum FBgn0001672 l(1)EN9 lethal (1) from Eugene Nonautonomous 9 http://flybase.org/reports/FBgn0001672 - gene - - - l(1)EN9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval fat body,Malpighian tubule,embryonic/larval salivary gland,embryonic/larval cuticle" FBgn0040110 l(3)tk12 lethal (3) tk12 http://flybase.org/reports/FBgn0040110 gene - - - "tk12, l(3)tk12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024315 Picot Picot http://flybase.org/reports/FBgn0024315 - protein_coding_gene phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from electronic annotation with InterPro:IPR004745 transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 phosphate ion transmembrane transport ; GO:0035435 | inferred from electronic annotation with InterPro:IPR004745 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "picot, CG8098, Picot, MFS8" "IPR004745:Na-dependent inorganic phosphate cotransporter, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8098 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-513e17.1, Drer\slc17a6a, Drer\slc17a7a, Drer\slc17a9a, Drer\slc17a6b, Drer\slc17a8, Drer\slc17a5, Drer\ppt1" "Scer\TNA1, Scer\YIL166C, Scer\THI73, Scer\YCT1, Scer\SEO1, Scer\DAL5" "Cele\slc-17.9, Cele\F10C2.7, Cele\slc-17.1, Cele\slc-17.5, Cele\T02B11.6, Cele\T22F3.8, Cele\C39E9.7, Cele\K08C7.1, Cele\D1046.4, Cele\Y15E3A.4, Cele\W04C9.6, Cele\M162.5, Cele\C35A5.3, Cele\C01B4.7, Cele\Y4C6B.3, Cele\R10D12.1, Cele\eat-4, Cele\Y19D10A.11, Cele\cima-1, Cele\F41C3.2, Cele\C18H9.5, Cele\F44E7.7, Cele\Y19D10A.4, Cele\slc-17.3, Cele\T22F3.11, Cele\T28H11.8, Cele\F56A4.12, Cele\Y51B9A.6, Cele\vglu-3, Cele\T19D12.9, Cele\Y19D10A.5, Cele\C18D1.2, Cele\M117.1, Cele\vglu-2, Cele\T27D12.1, Cele\K11G9.5, Cele\C01B4.8, Cele\Y4C6B.4, Cele\T22F3.7, Cele\T22F3.10, Cele\T19D12.10, Cele\slc-17.4, Cele\F11A5.9, Cele\T01H3.3, Cele\Y19D10A.8, Cele\F56A4.10, Cele\slc-17.8, Cele\H11E01.2, Cele\slc-17.2, Cele\F59A1.13" Xtro\slc17a7 "Mmus\Slc17a5, Mmus\Slc17a7, Mmus\Slc17a1, Mmus\Slc17a6, Mmus\Slc17a2, Mmus\Slc17a3, Mmus\Slc17a8, Mmus\Slc17a4" "Hsap\SLC17A4, Hsap\SLC17A3, Hsap\SLC17A5, Hsap\SLC17A7, Hsap\SLC17A2, Hsap\SLC17A6, Hsap\SLC17A1, Hsap\SLC17A8" "lethal,viable" DRSC07508 I -0.550793728 1.57249148 1.122309429 0.412384486 -0.612761317 -0.264277534 FBgn0001063 Fs(3)Pud Female sterile (3) Pudur http://flybase.org/reports/FBgn0001063 - gene molecular_function ; GO:0003674 | no biological data available embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Pud, Fs(3)Pudur, Fs(3)Sz29, Fs(3)Pud" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0034867 CG13557 - http://flybase.org/reports/FBgn0034867 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13557 - CG13557 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026630 nes nessy http://flybase.org/reports/FBgn0026630 - protein_coding_gene lysophospholipid acyltransferase activity ; GO:0071617 | inferred from direct assay plasma membrane organization ; GO:0007009 | inferred from genetic interaction with oys sperm individualization ; GO:0007291 | inferred from genetic interaction with oys germ cell migration ; GO:0008354 | inferred from genetic interaction with oys lipid modification ; GO:0030258 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement "CG9655, nes, Nes" "IPR004299:Membrane bound O-acyl transferase, MBOAT" CG9655 11-Aug-17 DroID_v2017_08 Drer\lpcat3 Scer\ALE1 Cele\mboa-6 Xtro\lpcat3 Mmus\Lpcat3 Hsap\LPCAT3 " embryonic stage | stage 6-7 , embryonic stage -- adult stage , embryonic stage , embryonic stage | early , embryonic stage | stage 7-12 , embryonic stage | stage >=13 " " mesectoderm anlage

, cephalic furrow

,

ubiquitous , mesoderm

, visceral mesoderm

, endoderm

" "viable,fertile" embryo FBgn0036416 CG7924 - http://flybase.org/reports/FBgn0036416 protein_coding_gene - - - CG7924 "IPR002350:Kazal domain, IPR002989:Mycobacterial pentapeptide repeat" CG7924 11-Aug-17 DroID_v2017_08 Drer\LOC100334275 - - - - - viable FBgn0029763 Usp16-45 Ubiquitin specific protease 16/45 http://flybase.org/reports/FBgn0029763 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001607 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:20080 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:20080 cellular_component ; GO:0005575 | no biological data available "CG4165, Usp16-45, Usp16, Usp45, USP45, Q9W4C3" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR001607:Zinc finger, UBP-type, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4165 11-Aug-17 DroID_v2017_08 "Drer\usp45, Drer\usp16" "Scer\UBP5, Scer\DOA4" Cele\cyk-3 "Xtro\usp16, Xtro\usp45" "Mmus\Usp45, Mmus\Usp16" "Hsap\USP16, Hsap\USP45" "visible,partially lethal - majority die,some die during pupal stage,short lived,locomotor behavior defective" "trichogen cell,mesothoracic tergum" FBgn0036612 CG4998 - http://flybase.org/reports/FBgn0036612 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH66, CG4998" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG4998 11-Aug-17 DroID_v2017_08 - - Cele\svh-1 Xtro\prss2 "Mmus\Prss44, Mmus\Prss29, Mmus\Prss42" "Hsap\PRSS42, Hsap\PLG" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC22911 K 0.058881863 0.681098197 -0.56995951 0.144411574 -0.828105717 -2.002806659 FBgn0011530 l(2)06424 lethal (2) 06424 http://flybase.org/reports/FBgn0011530 - gene - - - l(2)06424 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0283651 CG46301 - http://flybase.org/reports/FBgn0283651 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:16106 "CG46301, CG16879, DS01759.1, BG:DS01759.1, CG17341, BG:DS01523.1" "IPR008845:Sporozoite P67 surface antigen, IPR026746:Nucleolar protein 4-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG46301 11-Aug-17 DroID_v2017_08 "Drer\nol4la, Drer\nol4lb" - "Cele\C33G3.6, Cele\C27C7.1" "Xtro\nol4, Xtro\nol4l" "Mmus\Nol4l, Mmus\Nol4" "Hsap\NOL4L, Hsap\NOL4" FBgn0039081 Irk2 Inwardly rectifying potassium channel 2 http://flybase.org/reports/FBgn0039081 protein_coding_gene inward rectifier potassium channel activity ; GO:0005242 | inferred from biological aspect of ancestor with PANTHER:PTN000205946 inward rectifier potassium channel activity ; GO:0005242 | inferred from direct assay regulation of membrane potential ; GO:0042391 | inferred from direct assay potassium ion import ; GO:0010107 | inferred from biological aspect of ancestor with PANTHER:PTN000205946 potassium ion transport ; GO:0006813 | inferred from direct assay wing disc development ; GO:0035220 | inferred from mutant phenotype negative regulation of decapentaplegic signaling pathway ; GO:0090099 | inferred from genetic interaction with dpp inferred from genetic interaction with tkv neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000205946 "dKirII, irk2, CG10180, CG4370, Irk2, dKir" "IPR013518:Potassium channel, inwardly rectifying, Kir, cytoplasmic, IPR014756:Immunoglobulin E-set, IPR016449:Potassium channel, inwardly rectifying, Kir" CG4370 11-Aug-17 DroID_v2017_08 "Drer\kcnj15, Drer\kcnj13, Drer\kcnj5, Drer\kcnj11l, Drer\kcnj2b, Drer\kcnj14, Drer\kcnj8, Drer\kcnj1a.5, Drer\kcnj1a.2, Drer\kcnj12b, Drer\LOC103910156, Drer\kcnj1a.1, Drer\si:dkey-106c17.3, Drer\kcnj11, Drer\kcnj3a, Drer\kcnj1a.6, Drer\kcnj6, Drer\zgc:162160, Drer\kcnj12a, Drer\kcnj10a, Drer\kcnj9, Drer\kcnj16, Drer\kcnj1a.4, Drer\kcnj1b, Drer\kcnj2a, Drer\LOC103909814, Drer\si:dkey-100n10.2, Drer\kcnj3b, Drer\si:ch211-113j13.2, Drer\kcnj1a.3" - "Cele\irk-1, Cele\irk-2, Cele\irk-3" "Xtro\kcnj12, Xtro\kcnj14, Xtro\kcnj3, Xtro\kcnj10, Xtro\kcnj13, Xtro\kcnj9, Xtro\kcnj1, Xtro\kcnj16, Xtro\kcnj2, Xtro\kcnj11, Xtro\kcnj15, Xtro\kcnj4" "Mmus\Kcnj15, Mmus\Kcnj4, Mmus\Kcnj2, Mmus\Kcnj10, Mmus\Kcnj1, Mmus\Kcnj13, Mmus\Kcnj6, Mmus\Kcnj8, Mmus\Kcnj14, Mmus\Kcnj9, Mmus\Kcnj12, Mmus\Kcnj3, Mmus\Kcnj5, Mmus\Kcnj11, Mmus\Kcnj16" "Hsap\KCNJ13, Hsap\KCNJ4, Hsap\KCNJ5, Hsap\KCNJ11, Hsap\KCNJ14, Hsap\KCNJ9, Hsap\KCNJ12, Hsap\KCNJ3, Hsap\KCNJ16, Hsap\KCNJ18, Hsap\KCNJ15, Hsap\KCNJ10, Hsap\KCNJ2, Hsap\KCNJ8, Hsap\KCNJ1, Hsap\KCNJ6" "visible,size defective,cell death defective,partially lethal - majority die,some die during larval stage,cold sensitive,lethal,viable" "wing,wing vein,wing hinge,wing margin bristle,wing blade,wing vein L5,posterior crossvein,wing vein L2,wing vein L3,wing vein L4,wing disc | third instar larval stage" FBgn0024876 l(2)52Fe lethal (2) 52Fe http://flybase.org/reports/FBgn0024876 - gene - - - "E6.17, l(2)52Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005112 l(1)6 lethal (1) 6 http://flybase.org/reports/FBgn0005112 - gene - - - l(1)6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065723 l(2)SH0566 lethal (2) SH0566 http://flybase.org/reports/FBgn0065723 gene - - - "l(2)SH0566, l(2)SH2 0566" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030398 Cpr11B Cuticular protein 11B http://flybase.org/reports/FBgn0030398 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr11B, CG2555, DmelCpr11B" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2555 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\math-34, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - "viable,fertile" FBgn0005686 rug rugged http://flybase.org/reports/FBgn0005686 - gene - compound eye development ; GO:0048749 | inferred from mutant phenotype - rug - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "eye,ommatidium" FBgn0010075 Ms(2)M Male sterile (2) of Meyer http://flybase.org/reports/FBgn0010075 - gene - - - "Ms, Ms(2)M" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,dominant,female fertile" FBgn0065686 l(2)SH0656 lethal (2) SH0656 http://flybase.org/reports/FBgn0065686 gene - - - l(2)SH0656 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035856 CG13679 - http://flybase.org/reports/FBgn0035856 protein_coding_gene - - - "BcDNA:RE17113, CG13679" - CG13679 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0050229 tRNA:Leu-AAG-1-4 transfer RNA:Leucine-AAG 1-4 http://flybase.org/reports/FBgn0050229 tRNA_gene CUU codon-amino acid adaptor activity ; GO:0033417 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033417 cytosol ; GO:0005829 | inferred by curator from GO:0033417 "AE002787.trna49-LeuAAG, tRNA:L:AAG:AE002787-d, CR30229, chr2R.trna32-LeuAAG, tRNA-Leu-AAG-1-4, tRNA:Leu-AAG-1-4, tRNA:CR30229, CUU" - CR30229 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014280 l(2)vsp lethal (2) very small puparia http://flybase.org/reports/FBgn0014280 - gene - - - "l(2)60A-G, l(2)vsp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039684 Obp99d Odorant-binding protein 99d http://flybase.org/reports/FBgn0039684 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 autophagic cell death ; GO:0048102 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "CG15505, Obp99c, 99d, CG155505, Obp99d, DmelObp99d" IPR006170:Pheromone/general odorant binding protein CG15505 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,viable" FBgn0267542 CR45882 - http://flybase.org/reports/FBgn0267542 non_protein_coding_gene - - - CR45882 - CR45882 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040128 l(2)22Ak lethal (2) 22Ak http://flybase.org/reports/FBgn0040128 gene - - - "G, l(2)22Ak" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028848 CG7311 - http://flybase.org/reports/FBgn0028848 protein_coding_gene glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from electronic annotation with InterPro:IPR000447 glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from sequence or structural similarity "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000447, InterPro:IPR006076, InterPro:IPR023753 glycerol-3-phosphate metabolic process ; GO:0006072 | inferred from electronic annotation with InterPro:IPR000447" glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR000447 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity "BG:DS08249.2, CG7311, alpha-GPO, Gpo, GPO, GPO-3, gpo-3" "IPR000447:FAD-dependent glycerol-3-phosphate dehydrogenase, IPR006076:FAD dependent oxidoreductase, IPR031656:Alpha-glycerophosphate oxidase, C-terminal, IPR023753:FAD/NAD(P)-binding domain" CG7311 11-Aug-17 DroID_v2017_08 Drer\gpd2 Scer\GUT2 "Cele\Y50E8A.6, Cele\T25G3.4" Xtro\gpd2 Mmus\Gpd2 Hsap\GPD2 viable FBgn0053969 CG33969 - http://flybase.org/reports/FBgn0053969 protein_coding_gene - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from biological aspect of ancestor with PANTHER:PTN002307191 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN002307191 "CG5571, CG32429, CG33969" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011042:Six-bladed beta-propeller, TolB-like, IPR032675:Leucine-rich repeat domain, L domain-like" CG33969 11-Aug-17 DroID_v2017_08 Drer\fbxw4 "Scer\UFO1, Scer\MFB1" - Xtro\fbxw4 Mmus\Fbxw4 Hsap\FBXW4 viable FBgn0002358 l(3)87Ef lethal (3) 87Ef http://flybase.org/reports/FBgn0002358 - gene - - - "m32, l(3)m32, l(3)87Ef" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263999 CG43742 - http://flybase.org/reports/FBgn0263999 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 molecular_function ; GO:0003674 | no biological data available" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available CG43742 "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan" CG43742 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030525 CG10996 - http://flybase.org/reports/FBgn0030525 protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718 aldose 1-epimerase activity ; GO:0004034 | inferred from biological aspect of ancestor with PANTHER:PTN000009552" galactose catabolic process via UDP-galactose ; GO:0033499 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 glucose metabolic process ; GO:0006006 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 - CG10996 "IPR008183:Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013:Galactose mutarotase-like domain, IPR014718:Glycoside hydrolase-type carbohydrate-binding" CG10996 11-Aug-17 DroID_v2017_08 "Drer\galm, Drer\rfng, Drer\mfng, Drer\lfng" "Scer\YNR071C, Scer\YHR210C, Scer\GAL10" "Cele\C01B4.6, Cele\Y19D10A.16" "Xtro\galm, Xtro\rfng, Xtro\lfng" "Mmus\Lfng, Mmus\Galm, Mmus\Rfng, Mmus\Mfng" "Hsap\LFNG, Hsap\RFNG, Hsap\GALM, Hsap\MFNG" viable FBgn0035244 ABCB7 ATP binding cassette subfamily B member 7 http://flybase.org/reports/FBgn0035244 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 heme transporter activity ; GO:0015232 | inferred from sequence or structural similarity with UniProtKB:O75027 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O75027" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 heme transport ; GO:0015886 | inferred from sequence or structural similarity with UniProtKB:O75027 iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with UniProtKB:O75027 cellular iron ion homeostasis ; GO:0006879 | inferred from biological aspect of ancestor with PANTHER:PTN000657864 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011527 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000657864 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:O75027 "ABCB7, CG7955, dABCB7" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG7955 11-Aug-17 DroID_v2017_08 "Drer\abcb7, Drer\abcb6b, Drer\abcb6a" Scer\ATM1 "Cele\hmt-1, Cele\abtm-1" "Xtro\abcb6, Xtro\abcb7" "Mmus\Abcb7, Mmus\Abcb6" "Hsap\ABCB7, Hsap\ABCB6" viable DRSC08603 K 0.323729714 -0.074946061 0.333887392 -0.409660091 2.039088893 -0.326704885 FBgn0028206 l(3)S012613a lethal (3) S012613a http://flybase.org/reports/FBgn0028206 gene - - - "0126/13, l(3)S012613, l(3)S012613a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031630 CG15629 - http://flybase.org/reports/FBgn0031630 protein_coding_gene - - - CG15629 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG15629 11-Aug-17 DroID_v2017_08 "Drer\rdh10b, Drer\dhrs3b, Drer\rdh20, Drer\dhrs3a, Drer\sdr16c5a, Drer\si:dkey-221h15.4, Drer\rdh10a, Drer\sdr16c5b" "Scer\TDA5, Scer\YDL114W" "Cele\dhs-19, Cele\dhs-29, Cele\dhs-4, Cele\dhs-3" "Xtro\dhrs3, Xtro\hsd17b13, Xtro\rdh10, Xtro\hsd17b11, Xtro\sdr16c5" "Mmus\Sdr16c5, Mmus\Hsd17b13, Mmus\Rdh10, Mmus\Hsd17b11, Mmus\Sdr16c6, Mmus\Dhrs3" "Hsap\RDH10, Hsap\DHRS3, Hsap\HSD17B11, Hsap\HSD17B13, Hsap\SDR16C5" viable FBgn0011457 l(3)neo20 lethal (3) neo20 http://flybase.org/reports/FBgn0011457 - gene - - - l(3)neo20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003953 unp unexpanded http://flybase.org/reports/FBgn0003953 - gene - - - unp - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,viable,male,poor,female,visible" "wing,pronotum" FBgn0045471 Gr92a Gustatory receptor 92a http://flybase.org/reports/FBgn0045471 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity with Gr5a taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "DmGr92a, CG31208, Gr92D1, Gr92a, GR92a" IPR013604:7TM chemoreceptor CG31208 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - "partially lethal - majority die,some die during pupal stage" FBgn0266490 CG45089 - http://flybase.org/reports/FBgn0266490 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45089, Dromel_CG18624_FBtr0071140_uORF" - CG45089 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040633 CG12451 - http://flybase.org/reports/FBgn0040633 protein_coding_gene - - - CG12451 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027156 l(2)ch lethal (2) ch http://flybase.org/reports/FBgn0027156 - gene - - - l(2)ch - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024679 l(1)LefEM27 lethal (1) LefEM27 http://flybase.org/reports/FBgn0024679 - gene - - - "EM27, l(1)LefEM27" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036314 Sf3a2 Splicing factor 3a subunit 2 http://flybase.org/reports/FBgn0036314 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000690, InterPro:IPR003604 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:10766" "positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000574843" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000574843 U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000002201 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000574843 "CG10754, Sf3a2, SF3A2" "IPR000690:Matrin/U1-C, C2H2-type zinc finger, IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013087:Zinc finger C2H2-type, IPR031781:SF3A2 domain" CG10754 11-Aug-17 DroID_v2017_08 Drer\sf3a2 Scer\PRP11 Cele\repo-1 Xtro\sf3a2 Mmus\Sf3a2 Hsap\SF3A2 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,wing" DRSC09801 K -0.130920703 1.315523647 -1.258309124 -0.338081644 -1.85800193 -0.217056313 FBgn0020639 Lcp65Af Lcp65Af http://flybase.org/reports/FBgn0020639 FBgn0035682 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence or structural similarity structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG10533, DCP7, DMLCP65f, Lcp-f, Lcp65Af, DmelLcp65Af" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG10533 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - " embryonic stage , larval stage " FBgn0024642 l(2)k11560 lethal (2) k11560 http://flybase.org/reports/FBgn0024642 - gene - - - "115/60, l(2)k11560" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,trichome" FBgn0032996 CG17479 - http://flybase.org/reports/FBgn0032996 protein_coding_gene - - - CG17479 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250735 l(3)S023931 lethal (3) S023931 http://flybase.org/reports/FBgn0250735 gene - - - "l(3)S023931, l(3)s023931" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260441 RpS12 Ribosomal protein S12 http://flybase.org/reports/FBgn0260441 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000530 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000530 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000530 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CG11271, S12, RS12, l(3)s2783, BcDNA:RH29995, RpS12E, RpS12" "IPR000530:Ribosomal protein S12e, IPR004038:Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR029064:50S ribosomal protein L30e-like" CG11271 11-Aug-17 DroID_v2017_08 "Drer\rps12, Drer\rsrc1" Scer\RPS12 Cele\rps-12 Xtro\rps12 "Mmus\Rsrc1, Mmus\Rps12" "Hsap\RSRC1, Hsap\RPS12" "lethal,recessive" DRSC11270 IEK -2.425239312 -2.203312862 0.146312604 -5.374508049 0.602711103 2.083385557 FBgn0060525 l(3)S101904b lethal (3) S101904b http://flybase.org/reports/FBgn0060525 gene - - - "1019/04, l(3)S101904b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262407 mir-308 mir-308 stem loop http://flybase.org/reports/FBgn0262407 miRNA_gene - negative regulation of translation ; GO:0017148 | inferred from mutant phenotype - "mir-308, miR-308, 308, CR42951, CR33612, dme-mir-308, dme-miR-308" - CR42951 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,partially lethal - majority die" wing FBgn0005364 tr261 triangle 261 http://flybase.org/reports/FBgn0005364 - gene - - - "tr-261, tr261" - - 11-Aug-17 DroID_v2017_08 - - - - - - "crossvein,ectopic" FBgn0033769 CG8768 - http://flybase.org/reports/FBgn0033769 protein_coding_gene coenzyme binding ; GO:0050662 | inferred from electronic annotation with InterPro:IPR001509 catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001509 - - CG8768 "IPR001509:NAD-dependent epimerase/dehydratase, IPR010099:Epimerase family protein SDR39U1, IPR013549:Domain of unknown function DUF1731, IPR016040:NAD(P)-binding domain" CG8768 11-Aug-17 DroID_v2017_08 Drer\sdr39u1 - - Xtro\sdr39u1 Mmus\Sdr39u1 Hsap\SDR39U1 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0265305 CR44278 - http://flybase.org/reports/FBgn0265305 non_protein_coding_gene - - - "CR44278, lincRNA.274" - CR44278 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265265 CG32727 - http://flybase.org/reports/FBgn0265265 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32727, anon-SAGE:Wang-041" IPR001623:DnaJ domain CG32727 11-Aug-17 DroID_v2017_08 "Drer\dnajc19, Drer\dnajc15" "Scer\PAM18, Scer\MDJ2" Cele\dnj-21 "Xtro\dnajc15, Xtro\dnajc19" "Mmus\Dnajc15, Mmus\Dnajc19" "Hsap\DNAJC19, Hsap\DNAJC15" FBgn0264658 piddling piddling http://flybase.org/reports/FBgn0264658 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - piddling - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0028217 l(3)S008224 lethal (3) S008224 http://flybase.org/reports/FBgn0028217 gene - - - "0082/24, l(3)S008224" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265262 Vha68-1 Vacuolar H[+] ATPase 68kD subunit 1 http://flybase.org/reports/FBgn0265262 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000389800" "ATP metabolic process ; GO:0046034 | inferred from electronic annotation with InterPro:IPR004100, InterPro:IPR022878 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000793, InterPro:IPR005725 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with l(2)gd1 vacuolar acidification ; GO:0007035 | inferred from sequence or structural similarity with UniProtKB:P17255" "proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity with Vha68-2 lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN001032512 vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD:S000002344 plasma membrane ; GO:0005886 | inferred from direct assay" "VhaA, CG12403, Vha68, vha67-1, A subunit, Vha68-1, vha68-1, Vha, Vha-68-1, ATP6V1A" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR023366:ATP synthase subunit alpha-like domain, IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005725:ATPase, V1 complex, subunit A, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR024034:ATPase, F1/V1 complex, beta/alpha subunit, C-terminal, IPR022878:V-type ATP synthase catalytic alpha chain, IPR031686:ATPsynthase alpha/beta subunit, N-terminal extension" CG12403 11-Aug-17 DroID_v2017_08 "Drer\atp6v1aa, Drer\atp6v1ab" Scer\VMA1 Cele\vha-13 Xtro\atp6v1a Mmus\Atp6v1a Hsap\ATP6V1A FBgn0082613 Su(PDS)P86 Su(PDS)P86 http://flybase.org/reports/FBgn0082613 gene - - - Su(PDS)P86 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation" FBgn0058311 CG40311 - http://flybase.org/reports/FBgn0058311 protein_coding_gene - - - CG40311 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267149 CR45589 - http://flybase.org/reports/FBgn0267149 non_protein_coding_gene - - - "lincRNA.766, CR45589" - CR45589 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060775 l(3)S060914 lethal (3) S060914 http://flybase.org/reports/FBgn0060775 gene - - - "0609/14, l(3)S060914" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267655 CR45993 - http://flybase.org/reports/FBgn0267655 non_protein_coding_gene - - - CR45993 - CR45993 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067043 U4 U4 http://flybase.org/reports/FBgn0067043 gene - - - U4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,partially lethal - majority die" "chaeta,eye" FBgn0038613 Vha100-4 Vacuolar H[+] ATPase 100kD subunit 4 http://flybase.org/reports/FBgn0038613 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000005796 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000179505" vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence or structural similarity with SGD:S000005796 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000907964 vacuolar proton-transporting V-type ATPase complex ; GO:0016471 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000005796" "vha100-4, CG7678, Vha100-4" "IPR002490:V-type ATPase, V0 complex, 116kDa subunit family, IPR026028:ATPase, V0 complex, subunit 116kDa, eukaryotic" CG7678 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-173p19.2, Drer\atp6v0a1b, Drer\atp6v0a2b, Drer\atp6v0a1a, Drer\tcirg1b, Drer\tcirg1a, Drer\atp6v0a2a" "Scer\STV1, Scer\VPH1" "Cele\unc-32, Cele\vha-5, Cele\vha-7, Cele\vha-6" "Xtro\tcirg1, Xtro\atp6v0a1, Xtro\atp6v0a4, Xtro\atp6v0a2" "Mmus\Tcirg1, Mmus\Atp6v0a1, Mmus\Atp6v0a4, Mmus\Atp6v0a2" "Hsap\ATP6V0A1, Hsap\TCIRG1, Hsap\ATP6V0A4, Hsap\ATP6V0A2" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0001051 Fs(3)Hub Female sterile (3) Huba http://flybase.org/reports/FBgn0001051 - gene molecular_function ; GO:0003674 | no biological data available embryonic cleavage ; GO:0040016 | inferred from mutant phenotype pronuclear fusion ; GO:0007344 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Hub, Fs(3)Huba, Fs(3)Sz12, Fs(3)Hub" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "female pronucleus | maternal effect,cleavage stage embryo,maternal effect,male pronucleus | maternal effect" FBgn0038324 CG5038 - http://flybase.org/reports/FBgn0038324 protein_coding_gene - biological_process ; GO:0008150 | no biological data available - CG5038 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR013618:Domain of unknown function DUF1736, IPR019734:Tetratricopeptide repeat" CG5038 11-Aug-17 DroID_v2017_08 "Drer\tmtc4, Drer\tmtc2b, Drer\tmtc1, Drer\tmtc2a" - Cele\F38B6.6 "Xtro\tmtc2, Xtro\tmtc4" "Mmus\Tmtc4, Mmus\Tmtc2" "Hsap\TMTC4, Hsap\TMTC2" FBgn0061137 l(3)S000903 lethal (3) S000903 http://flybase.org/reports/FBgn0061137 gene - - - "0009/03, l(3)S000903" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0086916 snky sneaky http://flybase.org/reports/FBgn0086916 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model "sperm chromatin decondensation ; GO:0035041 | inferred from mutant phenotype sperm plasma membrane disassembly ; GO:0035045 | inferred from mutant phenotype fertilization, exchange of chromosomal proteins ; GO:0035042 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012858 acrosomal vesicle ; GO:0001669 | inferred from direct assay "snky, CG11281, ms(3)snky, ms(3)ry4, ms(3)sneaky, ms(3)4, Snky" IPR012858:Dendritic cell-specific transmembrane protein-like CG11281 11-Aug-17 DroID_v2017_08 "Drer\dcst1, Drer\ocstamp, Drer\dcst2" - "Cele\K12B6.2, Cele\srh-97, Cele\spe-42" "Xtro\LOC101732050, Xtro\LOC101731982, Xtro\LOC101734522, Xtro\LOC101734054" "Mmus\Ocstamp, Mmus\Dcstamp, Mmus\Dcst1" "Hsap\DCSTAMP, Hsap\OCSTAMP, Hsap\DCST1, Hsap\DCST2" FBgn0010763 l(3)01859 lethal (3) 01859 http://flybase.org/reports/FBgn0010763 - gene - - - l(3)01859 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065823 l(2)SH0364 lethal (2) SH0364 http://flybase.org/reports/FBgn0065823 gene - - - "l(2)SH0364, SH2 0364" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260588 2L3186 - http://flybase.org/reports/FBgn0260588 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3186 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0014318 l(3)ry127 lethal (3) ry127 http://flybase.org/reports/FBgn0014318 - gene - - - l(3)ry127 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039381 SppL Signal peptide peptidase-like http://flybase.org/reports/FBgn0039381 protein_coding_gene "aspartic endopeptidase activity, intramembrane cleaving ; GO:0042500 | inferred from direct assay" signal peptide processing ; GO:0006465 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi-associated vesicle membrane ; GO:0030660 | inferred from biological aspect of ancestor with PANTHER:PTN000256093 integral component of lumenal side of endoplasmic reticulum membrane ; GO:0071556 | inferred from biological aspect of ancestor with PANTHER:PTN000256093 Golgi apparatus ; GO:0005794 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN000256093 membrane ; GO:0016020 | inferred from direct assay integral component of cytoplasmic side of endoplasmic reticulum membrane ; GO:0071458 | inferred from biological aspect of ancestor with PANTHER:PTN000256093 "CG5901, CG17370, SPPL3, sppL, SppL, Sppl" "IPR006639:Presenilin/signal peptide peptidase, IPR007369:Peptidase A22B, signal peptide peptidase" CG17370 11-Aug-17 DroID_v2017_08 "Drer\sppl2, Drer\hm13, Drer\sppl3" Scer\YPF1 "Cele\imp-1, Cele\imp-2" "Xtro\sppl3, Xtro\hm13, Xtro\sppl2a" "Mmus\Sppl2b, Mmus\Sppl3, Mmus\H13, Mmus\Sppl2a" "Hsap\SPPL3, Hsap\HM13" "viable,fertile" FBgn0042625 zaro-4 zaro-4 http://flybase.org/reports/FBgn0042625 gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available zaro-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086060 snoRNA:Me28S-U1554 - http://flybase.org/reports/FBgn0086060 snoRNA_gene - - - "snoRNA:Me28S-U1554, Me28S-Um1554, CR34689" - CR34689 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086362 spn-F spn-F http://flybase.org/reports/FBgn0086362 protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V3Y8 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24117 inferred from physical interaction with UniProtKB:Q9V3Y8 ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from direct assay" oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype positive regulation of neuron remodeling ; GO:1904801 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype cellular protein localization ; GO:0034613 | inferred from mutant phenotype oocyte axis specification ; GO:0007309 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from direct assay oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "spn-F, CG12114, 1130/03, l(3)S113003b, Spn-F, SpnF" - CG12114 11-Aug-17 DroID_v2017_08 Drer\ift74 - Cele\ifa-1 - - - DRSC14475 E 0.94910467 -0.679165847 0.350719155 -2.652246509 0.196422755 0.076141319 FBgn0036194 CG11652 - http://flybase.org/reports/FBgn0036194 protein_coding_gene molecular_function ; GO:0003674 | no biological data available peptidyl-diphthamide biosynthetic process from peptidyl-histidine ; GO:0017183 | inferred from biological aspect of ancestor with PANTHER:PTN000079945 peptidyl-diphthamide biosynthetic process from peptidyl-histidine ; GO:0017183 | inferred from sequence or structural similarity with SGD:S000001365 phagocytosis ; GO:0006909 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000001365 "CG11652, Dph1" IPR016435:Diphthamide synthesis DPH1/DPH2 CG11652 11-Aug-17 DroID_v2017_08 "Drer\dph1, Drer\dph2" "Scer\DPH1, Scer\DPH2" Cele\dph-1 "Xtro\dph2, Xtro\dph1" "Mmus\Dph1, Mmus\Dph2" "Hsap\DPH2, Hsap\DPH1" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0000775 fs(1)A1245 female sterile (1) A1245 http://flybase.org/reports/FBgn0000775 - gene - - - "fs(1)1246, fs(1)A1245" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,viable,reduced,female sterile germline-dependent" "ovary,dorsal appendage" FBgn0038505 CG17283 - http://flybase.org/reports/FBgn0038505 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein autoprocessing ; GO:0016540 | inferred from electronic annotation with InterPro:IPR033145 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 autophagic cell death ; GO:0048102 | inferred from expression pattern protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern - CG17283 "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR033145:Cathepsin E, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG17283 11-Aug-17 DroID_v2017_08 "Drer\ren, Drer\zgc:103530, Drer\ctsd, Drer\nots, Drer\zgc:63831" "Scer\YPS1, Scer\YGL258W-A, Scer\YPS3, Scer\BAR1, Scer\YPS7, Scer\MKC7, Scer\YPS5, Scer\PEP4, Scer\YPS6" "Cele\asp-6, Cele\asp-10, Cele\asp-13, Cele\asp-17, Cele\asp-18, Cele\asp-9, Cele\asp-4, Cele\asp-15, Cele\asp-19, Cele\asp-2, Cele\asp-8, Cele\asp-12, Cele\asp-14, Cele\asp-3, Cele\asp-5, Cele\asp-7, Cele\asp-16, Cele\asp-1" "Xtro\pgc, Xtro\ren, Xtro\bace1, Xtro\pga4, Xtro\LOC496913, Xtro\napsa, Xtro\ctsd, Xtro\ctse, Xtro\bace2" "Mmus\Ren2, Mmus\Bace1, Mmus\Pga5, Mmus\Ctsd, Mmus\Pgc, Mmus\Cym, Mmus\Bace2, Mmus\Ctse, Mmus\Napsa, Mmus\Ren1" "Hsap\PGC, Hsap\PGA3, Hsap\REN, Hsap\CTSE, Hsap\BACE1, Hsap\PGA4, Hsap\PGA5, Hsap\BACE2, Hsap\NAPSA, Hsap\CTSD" viable FBgn0024671 l(2)k03117 lethal (2) k03117 http://flybase.org/reports/FBgn0024671 - gene - - - "31/17, l(2)k03117" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261833 CR42765 - http://flybase.org/reports/FBgn0261833 non_protein_coding_gene - - - "CG42765, CR42765" - CR42765 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058141 CG40141 - http://flybase.org/reports/FBgn0058141 protein_coding_gene - - - CG40141 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086287 GS2192 - http://flybase.org/reports/FBgn0086287 gene - - - "GS2192, 2192" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261402 Ir75b Ionotropic receptor 75b http://flybase.org/reports/FBgn0261402 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "IR75b, CG14586, DmelIR75b, CG14586-B, Ir75b, CG42643, IR75abc" IPR001320:Ionotropic glutamate receptor CG42643 11-Aug-17 DroID_v2017_08 "Drer\grid1b, Drer\LOC100537813, Drer\grid1a" - "Cele\glr-8, Cele\W02A2.5" - "Mmus\Grik4, Mmus\Grid1" Hsap\GRID1 FBgn0259295 EP-899 - http://flybase.org/reports/FBgn0259295 gene - - - EP-899 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0005188 l(2)S42A lethal of Seto 42A http://flybase.org/reports/FBgn0005188 - gene - - - l(2)S42A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "puparium,pupa" FBgn0267747 CR46078 - http://flybase.org/reports/FBgn0267747 non_protein_coding_gene - - - CR46078 - CR46078 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036962 CG17122 - http://flybase.org/reports/FBgn0036962 protein_coding_gene - - - CG17122 - CG17122 11-Aug-17 DroID_v2017_08 Drer\cfap157 - - Xtro\cfap157 Mmus\Cfap157 Hsap\CFAP157 viable DRSC10245 I 1.783136295 0.338456215 0.22987199 0.386180845 -0.37925313 -0.431721181 FBgn0039403 Sld5 Sld5 http://flybase.org/reports/FBgn0039403 protein_coding_gene 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay double-strand break repair via break-induced replication ; GO:0000727 | inferred from biological aspect of ancestor with PANTHER:PTN000476383 positive regulation of G1/S transition of mitotic cell cycle ; GO:1900087 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from biological aspect of ancestor with PANTHER:PTN000476383 neurogenesis ; GO:0022008 | inferred from mutant phenotype replication fork protection complex ; GO:0031298 | inferred from biological aspect of ancestor with PANTHER:PTN000476383 GINS complex ; GO:0000811 | inferred from direct assay "CG14549, Sld5, anon-WO0172774.61" "IPR008591:GINS complex subunit Sld5, IPR021151:GINS subunit, domain A, IPR031633:DNA replication complex GINS protein SLD5, C-terminal" CG14549 11-Aug-17 DroID_v2017_08 Drer\gins4 Scer\SLD5 Cele\sld-5 Xtro\gins4 Mmus\Gins4 Hsap\GINS4 "lethal,cell cycle defective,dominant,neuroanatomy defective,viable,visible" "embryonic/larval brain,embryonic/larval neuroblast,ganglion mother cell,chaeta" FBgn0001132 gra gravel http://flybase.org/reports/FBgn0001132 - gene - - - "spc, gra" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,eye,ommatidium,wing vein,marginal cell,2nd posterior cell,3rd posterior cell" FBgn0000693 flrdQ flight reduced Q http://flybase.org/reports/FBgn0000693 - gene - - - flrdQ - - 11-Aug-17 DroID_v2017_08 - - - - - - "jumping defective,hypoactive,flight defective" FBgn0039429 CG14238 - http://flybase.org/reports/FBgn0039429 protein_coding_gene - - - CG14238 IPR019169:Transmembrane protein 26 CG14238 11-Aug-17 DroID_v2017_08 "Drer\LOC101883956, Drer\tmem26a, Drer\tmem26b" - Cele\Y119C1B.3 "Xtro\tmem26, Xtro\LOC101733991" Mmus\Tmem26 Hsap\TMEM26 "viable,visible" "chaeta,supernumerary" DRSC14732 I -1.114302151 -1.601043976 -0.355736792 -1.106297579 0.051333658 -0.504436911 FBgn0036879 Cpr76Bb Cuticular protein 76Bb http://flybase.org/reports/FBgn0036879 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr76Bb, CG9290, DmelCpr76Bb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG9290 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0060316 l(3)S147410 lethal (3) S147410 http://flybase.org/reports/FBgn0060316 gene - - - "1474/10, l(3)S147410" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0260631 c02134 - http://flybase.org/reports/FBgn0260631 gene - - - c02134 - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0015926 dah discontinuous actin hexagon http://flybase.org/reports/FBgn0015926 FBgn0015590 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 cellularization ; GO:0007349 | traceable author statement actomyosin contractile ring assembly ; GO:0000915 | non-traceable author statement extrinsic component of membrane ; GO:0019898 | traceable author statement "Dah, CG6157, fs(1)dah, Apd, dah" "IPR000433:Zinc finger, ZZ-type, IPR015153:EF-hand domain, type 1, IPR011992:EF-hand domain pair" CG6157 11-Aug-17 DroID_v2017_08 Drer\dtnbb - Cele\dyb-1 - Mmus\Dytn Hsap\DYTN "viable,fertile,wild-type,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0263405 CR43451 - http://flybase.org/reports/FBgn0263405 non_protein_coding_gene - - - CR43451 - CR43451 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034455 CG11007 - http://flybase.org/reports/FBgn0034455 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11007 "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain" CG11007 11-Aug-17 DroID_v2017_08 "Drer\tmx2b, Drer\tmx2a" - Cele\C35D10.10 Xtro\tmx2 Mmus\Tmx2 Hsap\TMX2 viable DRSC06023 K -0.120194754 0.511220394 -0.035012019 0.810394297 -1.597080235 -0.264647667 FBgn0016956 tilM touch insensitive larva M http://flybase.org/reports/FBgn0016956 - gene - - - "line 310, tilM" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0275433 CR46265 - http://flybase.org/reports/FBgn0275433 non_protein_coding_gene - - - CR46265 - CR46265 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260938 tay tay bridge http://flybase.org/reports/FBgn0260938 protein_coding_gene - negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Ras85D inferred from genetic interaction with rl inferred from genetic interaction with Egfr inferred from genetic interaction with rho inferred from genetic interaction with Mkp3 inferred from physical interaction with rl inferred from physical interaction with Mkp3 adult walking behavior ; GO:0007628 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype pattern orientation ; GO:0007633 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "dAUTS2, CG9056, tay, XI, l(1)XI, l(1)13Ff, l(1)14Ac" - CG9056 11-Aug-17 DroID_v2017_08 "Drer\auts2a, Drer\auts2b, Drer\fbrsl1" - - - "Mmus\Auts2, Mmus\Fbrsl1" "Hsap\AUTS2, Hsap\FBRSL1, Hsap\FBRS" FBgn0058268 CG40268 - http://flybase.org/reports/FBgn0058268 protein_coding_gene - - - CG40268 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20994 E -0.388938958 -0.981455222 -3.406913178 -0.798662449 FBgn0065876 l(2)SH0241 lethal (2) SH0241 http://flybase.org/reports/FBgn0065876 gene - - - "l(2)SH0241, l(2)SH2 0241" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050463 CG30463 - http://flybase.org/reports/FBgn0050463 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from sequence or structural similarity with HGNC:4125 protein O-linked glycosylation ; GO:0006493 | inferred from sequence or structural similarity with HGNC:4125 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cytosol ; GO:0005829 | inferred from direct assay Golgi cisterna ; GO:0031985 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:4125 integral component of membrane ; GO:0016021 | inferred from sequence model "CG15713, CG8463, CG8456, CG30463, dppGalNAcT9" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG30463 11-Aug-17 DroID_v2017_08 "Drer\galnt14, Drer\galnt6, Drer\galnt18b, Drer\LOC101882942, Drer\poc1bl, Drer\galnt1, Drer\LOC103910015, Drer\galnt8b, Drer\galnt12, Drer\si:ch211-15e22.3, Drer\galnt11, Drer\LOC568645, Drer\LOC100535692, Drer\LOC101886587, Drer\galnt9, Drer\galnt3, Drer\galnt16, Drer\wbscr17, Drer\galnt2, Drer\galnt13, Drer\galnt10, Drer\LOC100334784, Drer\galnt8a.1, Drer\galnt7" - "Cele\gly-3, Cele\gly-7, Cele\gly-10, Cele\gly-11, Cele\gly-5, Cele\gly-9" "Xtro\galnt15, Xtro\galnt12, Xtro\galnt14, Xtro\galnt13, Xtro\galnt7, Xtro\galnt1, Xtro\wbscr17, Xtro\galnt2, Xtro\galnt4, Xtro\galnt10, Xtro\galnt9, Xtro\galnt16, Xtro\galnt6.1" "Mmus\Galnt9, Mmus\Galnt12, Mmus\Galnt7, Mmus\Wbscr17, Mmus\Galnt18, Mmus\Galnt13, Mmus\Galntl5, Mmus\Galnt2, Mmus\Galnt10, Mmus\Galnt3, Mmus\Galnt6, Mmus\Galntl6, Mmus\Galnt1, Mmus\Galnt15, Mmus\Galnt16, Mmus\Galnt4, Mmus\Galnt5, Mmus\Galnt11, Mmus\Galnt14" "Hsap\GALNT4, Hsap\POC1B-GALNT4, Hsap\GALNT13, Hsap\WBSCR17, Hsap\GALNTL5, Hsap\GALNT14, Hsap\GALNT15, Hsap\GALNT7, Hsap\GALNT2, Hsap\GALNT8, Hsap\GALNT18, Hsap\GALNT11, Hsap\GALNT3, Hsap\GALNT1, Hsap\GALNT6, Hsap\GALNT5, Hsap\GALNT12, Hsap\GALNT9, Hsap\GALNT16, Hsap\GALNTL6, Hsap\GALNT10" "lethal,partially lethal - majority die,viable" FBgn0067326 A43 A43 http://flybase.org/reports/FBgn0067326 gene - - - A43 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective,lethal,viable" "eye,pigment cell" FBgn0029581 CG3080 - http://flybase.org/reports/FBgn0029581 protein_coding_gene - - - CG3080 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040922 CG15036 - http://flybase.org/reports/FBgn0040922 protein_coding_gene - - - CG15036 - CG15036 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" DRSC17968 I -0.752092515 -2.412091698 -0.473370729 0.215032122 1.042428339 -0.155166299 FBgn0052732 CG32732 - http://flybase.org/reports/FBgn0052732 protein_coding_gene histone methyltransferase activity (H3-K36 specific) ; GO:0046975 | inferred from biological aspect of ancestor with PANTHER:PTN001777757 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001777757 histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | inferred from biological aspect of ancestor with PANTHER:PTN001777757 peptidyl-lysine monomethylation ; GO:0018026 | inferred from biological aspect of ancestor with PANTHER:PTN000327874 histone H3-K36 methylation ; GO:0010452 | inferred from biological aspect of ancestor with PANTHER:PTN001777757 peptidyl-lysine dimethylation ; GO:0018027 | inferred from biological aspect of ancestor with PANTHER:PTN001777757 lateral inhibition ; GO:0046331 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from biological aspect of ancestor with PANTHER:PTN001777757 peptidyl-lysine trimethylation ; GO:0018023 | inferred from biological aspect of ancestor with PANTHER:PTN001777757 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN001777757 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN001777757 "CG3042, CG12542, CG32732" "IPR015353:Rubisco LSMT, substrate-binding domain, IPR001214:SET domain" CG32732 11-Aug-17 DroID_v2017_08 "Drer\setd3, Drer\setd6, Drer\setd4" "Scer\EFM1, Scer\RKM3, Scer\RKM1, Scer\RKM2, Scer\RKM4" "Cele\set-27, Cele\set-29" "Xtro\setd4, Xtro\setd3, Xtro\setd6" "Mmus\Setd6, Mmus\Setd4, Mmus\Setd3" "Hsap\SETD3, Hsap\SETD4, Hsap\SETD6" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0263506 CR43495 - http://flybase.org/reports/FBgn0263506 non_protein_coding_gene - - - CR43495 - CR43495 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050407 tRNA:Gly-TCC-2-1 transfer RNA:Glycine-TCC 2-1 http://flybase.org/reports/FBgn0050407 tRNA_gene GGA codon-amino acid adaptor activity ; GO:0033463 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033463 cytosol ; GO:0005829 | inferred by curator from GO:0033463 "AE002575.trna11-GlyTCC, tRNA[Gly][[GGA]], tRNA:gly:58AB, tRNA:G:58AB, tRNA:G:TCC:AE002575-b, CR30205, CR30407, chr2R.trna55-GlyTCC, tRNA-Gly-TCC-2-1, tRNA:Gly-TCC-2-1, tRNA:CR30407, GGA" - CR30407 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038431 CG10405 - http://flybase.org/reports/FBgn0038431 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP155, CG10405" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG10405 11-Aug-17 DroID_v2017_08 Drer\si:dkey-78l4.5 - Cele\try-1 - "Mmus\Masp2, Mmus\Prss36, Mmus\Prss53, Mmus\Prss55" "Hsap\PRSS36, Hsap\TPSD1, Hsap\PRSS53" "viable,fertile" FBgn0004769 l(3)89Eh lethal (3) 89Eh http://flybase.org/reports/FBgn0004769 - gene - - - l(3)89Eh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262479 CG43069 - http://flybase.org/reports/FBgn0262479 protein_coding_gene protein tag ; GO:0031386 | inferred from biological aspect of ancestor with PANTHER:PTN001316528 protein sumoylation ; GO:0016925 | inferred from biological aspect of ancestor with PANTHER:PTN001316528 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001316528 "CG43069, chr2R_14750100_14750772.0" "IPR029071:Ubiquitin-related domain, IPR000626:Ubiquitin domain, IPR022617:Rad60/SUMO-like domain" CG43069 11-Aug-17 DroID_v2017_08 Drer\sumo1 Scer\SMT3 Cele\smo-1 - Mmus\Sumo1 Hsap\SUMO1 FBgn0042112 mRpL36 mitochondrial ribosomal protein L36 http://flybase.org/reports/FBgn0042112 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000000326 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with SGD:S000000326 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with SGD:S000000326 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000000326 "BcDNA:GM01757, CG18767, mRpL36" IPR000473:Ribosomal protein L36 CG18767 11-Aug-17 DroID_v2017_08 "Drer\mrpl36, Drer\uba2" "Scer\UBA2, Scer\RTC6" Cele\mrpl-36 Xtro\uba2 "Mmus\Uba2, Mmus\Mrpl36" "Hsap\UBA2, Hsap\MRPL36" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0053689 CG33689 - http://flybase.org/reports/FBgn0053689 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33689 IPR010512:Protein of unknown function DUF1091 CG33689 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0001478 l(1)9Ff lethal (1) 9Ff http://flybase.org/reports/FBgn0001478 - gene - - - "l(1)G3, l(1)9Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263404 CG43450 - http://flybase.org/reports/FBgn0263404 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43450 - CG43450 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000677 flrd397 flight reduced 397 http://flybase.org/reports/FBgn0000677 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "flrd-397, flrd397" - - 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,male,flight defective" FBgn0026343 Su(tkv*)3-3 Su(tkv*)3-3 http://flybase.org/reports/FBgn0026343 - gene - - - "Su(Tkv*)3-3, Su(tkv*)3-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263459 snoRNA:2R:9445410 - http://flybase.org/reports/FBgn0263459 snoRNA_gene - - - "snoRNA:2R:9445410, snoRNA:2R_9445410, ncRNA_50, chr2R:9073820..9074020" - CR43574 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266420 Ote Otefin http://flybase.org/reports/FBgn0266420 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Lam transcription corepressor activity ; GO:0003714 | inferred from mutant phenotype transcription factor binding ; GO:0008134 | inferred from physical interaction with Med "positive regulation of BMP signaling pathway ; GO:0030513 | inferred from genetic interaction with tkv oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype nuclear envelope reassembly ; GO:0031468 | inferred from direct assay germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype" nuclear periphery ; GO:0034399 | inferred from direct assay nuclear inner membrane ; GO:0005637 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay "Ote, CG5581, ote, hal, otefin, Otefin" "IPR003887:LEM domain, IPR011015:LEM/LEM-like domain" CG5581 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage " embryonic stage && pupal stage , oogenesis stage , embryonic stage -- adult stage , embryonic stage | early " FBgn0035435 PIG-C Phosphatidylinositol glycan anchor biosynthesis class C http://flybase.org/reports/FBgn0035435 protein_coding_gene phosphatidylinositol N-acetylglucosaminyltransferase activity ; GO:0017176 | inferred from electronic annotation with InterPro:IPR009450 catalytic activity ; GO:0003824 | inferred from biological aspect of ancestor with PANTHER:PTN000312400 GPI anchor biosynthetic process ; GO:0006506 | inferred from electronic annotation with InterPro:IPR009450 rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of Golgi to plasma membrane protein transport ; GO:0042996 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009450 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506 | inferred from biological aspect of ancestor with PANTHER:PTN000312400 "CG12077, PIG-C" IPR009450:Phosphatidylinositol N-acetylglucosaminyltransferase subunit C CG12077 11-Aug-17 DroID_v2017_08 Drer\pigc Scer\GPI2 Cele\T20D3.8 Xtro\pigc Mmus\Pigc Hsap\PIGC "lethal - all die before end of larval stage,viable" "rhabdomere,somatic clone" DRSC08241 I -1.522508011 -0.33410449 -0.675112907 1.473460836 -0.254619322 -0.108450507 FBgn0061359 CG33671 - http://flybase.org/reports/FBgn0061359 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006204, InterPro:IPR006205, InterPro:IPR006206 mevalonate kinase activity ; GO:0004496 | inferred from sequence or structural similarity with HGNC:7530 mevalonate kinase activity ; GO:0004496 | inferred from biological aspect of ancestor with PANTHER:PTN000048554" "isoprenoid biosynthetic process ; GO:0008299 | inferred from sequence or structural similarity with HGNC:7530 isopentenyl diphosphate biosynthetic process, mevalonate pathway ; GO:0019287 | inferred from biological aspect of ancestor with PANTHER:PTN000048554 cholesterol biosynthetic process ; GO:0006695 | inferred from biological aspect of ancestor with PANTHER:PTN000825262" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000048554 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:7530 "CG33009, CG8810, CG16804, CG16804b, CG33009-ORFB, CG33671, Dromel_CG33672_FBtr0091651_mORF, CG33009ORFB, MevK" "IPR006204:GHMP kinase N-terminal domain, IPR006205:Mevalonate kinase, IPR006206:Mevalonate/galactokinase, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR013750:GHMP kinase, C-terminal domain" CG33671 11-Aug-17 DroID_v2017_08 Drer\mvk Scer\ERG12 Cele\mvk-1 Xtro\mvk Mmus\Mvk Hsap\MVK FBgn0260008 UQCR-11 Ubiquinol-cytochrome c reductase 11 kDa subunit http://flybase.org/reports/FBgn0260008 protein_coding_gene ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:P07919 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000393767 "mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000393767 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:P07919 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000393767" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN000393767 mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:P07919 "CG41623, Ucrh, UCRH, UQCR-11" "IPR023184:Ubiquinol-cytochrome C reductase hinge domain, IPR003422:Cytochrome b-c1 complex, subunit 6" CG41623 11-Aug-17 DroID_v2017_08 Drer\uqcrh Scer\QCR6 Cele\T27E9.2 Xtro\uqcrh Mmus\Uqcrh "Hsap\UQCRHL, Hsap\UQCRH" FBgn0003234 ref(3)V refractory to sigma V http://flybase.org/reports/FBgn0003234 - gene - - - ref(3)V - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014901 anon-10Ah anon-10Ah http://flybase.org/reports/FBgn0014901 - gene - - - anon-10Ah - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263847 snRNA:LU small nuclear RNA Like U http://flybase.org/reports/FBgn0263847 snRNA_gene - - - "ncRNA_38, snRNA:LU, CR43708" - CR43708 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023155 Su(mg)2-4 Suppressor of modifier of gypsy 2-4 http://flybase.org/reports/FBgn0023155 - gene - - - Su(mg)2-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060649 l(3)S083603 lethal (3) S083603 http://flybase.org/reports/FBgn0060649 gene - - - "0836/03, l(3)S083603" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003682 ter terraced http://flybase.org/reports/FBgn0003682 - gene - - - ter - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "eye,ommatidium" FBgn0060830 l(3)S050217 lethal (3) S050217 http://flybase.org/reports/FBgn0060830 gene - - - "0502/17, l(3)S050217" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0264380 CR43832 - http://flybase.org/reports/FBgn0264380 non_protein_coding_gene - - - CR43832 - CR43832 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259852 Su(Ste):CR42421 Su(Ste):CR42421 http://flybase.org/reports/FBgn0259852 non_protein_coding_gene - - - "Su(Ste):CR42421, CR42421" - CR42421 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044825 R1A1-element\ORF1 R1A1-element ORF1 http://flybase.org/reports/FBgn0044825 transposable_element_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - "R1, R1A1-element\ORF1, R1-element\ORF1" "IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060430 l(3)S126104 lethal (3) S126104 http://flybase.org/reports/FBgn0060430 gene - - - "1261/04, l(3)S126104" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0035870 Gr66a Gustatory receptor 66a http://flybase.org/reports/FBgn0035870 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement response to insecticide ; GO:0017085 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | non-traceable author statement response to caffeine ; GO:0031000 | inferred from mutant phenotype response to L-canavanine ; GO:1901354 | inferred from mutant phenotype sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from direct assay "CG7189, Gr66C1, Gr66A, GR66C1, Gr66a, GR66a, GR66A, Gr66" IPR013604:7TM chemoreceptor CG7189 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0085589 CG41268 - http://flybase.org/reports/FBgn0085589 protein_coding_gene - - - CG41268 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028862 dao down and out http://flybase.org/reports/FBgn0028862 protein_coding_gene - - plasma membrane ; GO:0005886 | inferred from direct assay "BG:DS07295.2, anon-WO0140519.126, dao, CG15267" IPR011990:Tetratricopeptide-like helical domain CG15267 11-Aug-17 DroID_v2017_08 "Drer\smyd2b, Drer\smyd4, Drer\smyd2a, Drer\smyd1a, Drer\smyd3, Drer\smyd1b" "Scer\SET6, Scer\SET5" "Cele\set-18, Cele\set-10" "Xtro\smyd5, Xtro\smyd4, Xtro\smyd1" "Mmus\Smyd5, Mmus\Smyd1, Mmus\Smyd4, Mmus\Zmynd15, Mmus\Smyd3, Mmus\Smyd2" "Hsap\SMYD1, Hsap\SMYD4, Hsap\SMYD3, Hsap\ZMYND15, Hsap\SMYD5, Hsap\SMYD2" "paralytic,recessive,heat sensitive,neurophysiology defective,viable" dorsal medial muscle FBgn0041726 Rt1a\pol Rt1a element pol http://flybase.org/reports/FBgn0041726 transposable_element_gene - - - "ORF2, pilger\pol, Waldo-B\RTase, Rt1a\pol" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025148 ms(2)A8 ms(2)A8 http://flybase.org/reports/FBgn0025148 - gene - - - ms(2)A8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0004402 Datp Diadenosine tetraphosphatase http://flybase.org/reports/FBgn0004402 "FBgn0004226, FBgn0004238" gene bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity ; GO:0004081 | inferred from direct assay - - "Ap[[4]]A, Datp" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , adult stage && oogenesis stage " oocyte

FBgn0052373 CG32373 - http://flybase.org/reports/FBgn0052373 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" synaptic target recognition ; GO:0008039 | inferred from mutant phenotype - "BcDNA:RE64043, CG32373, CG3237" "IPR009030:Growth factor receptor cysteine-rich domain, IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000436:Sushi/SCR/CCP domain, IPR001881:EGF-like calcium-binding domain, IPR000742:EGF-like domain, IPR026823:Complement Clr-like EGF domain" CG32373 11-Aug-17 DroID_v2017_08 "Drer\LOC100535882, Drer\adgrl4, Drer\ltbp3, Drer\col28a1a, Drer\si:ch211-221n20.8, Drer\jag2a, Drer\dpy19l1l, Drer\matn3a, Drer\jag2b, Drer\zgc:158328, Drer\LOC562634, Drer\dlb, Drer\crb2a, Drer\crb2b, Drer\scube3, Drer\sned1, Drer\sez6l, Drer\sez6l2, Drer\megf6b, Drer\efemp1, Drer\adgrf6, Drer\si:dkey-163f14.6, Drer\scube1, Drer\fbln5, Drer\clec14a, Drer\svep1, Drer\si:ch73-173h19.3, Drer\fbln1, Drer\col28a1a, Drer\fbln7, Drer\jag1b, Drer\LOC100332841, Drer\jag1a" - Cele\F58E6.13 "Xtro\ltbp3, Xtro\f12, Xtro\svep1, Xtro\fbln5, Xtro\col14a1, Xtro\crb2, Xtro\ltbp4, Xtro\fbn1, Xtro\notch1, Xtro\matn4, Xtro\scube2, Xtro\scube1, Xtro\hgfac, Xtro\jag1, Xtro\nell1" "Mmus\Cfc1, Mmus\Vwa1, Mmus\Vwce, Mmus\Hgfac, Mmus\Dlk2, Mmus\Fbln5, Mmus\Ltbp1, Mmus\Cd93, Mmus\Dll4, Mmus\Jag1, Mmus\Vwde, Mmus\Gas6, Mmus\F12, Mmus\Habp2, Mmus\Dll3, Mmus\Selp, Mmus\Col22a1, Mmus\Sele, Mmus\Tdgf1, Mmus\Scube1, Mmus\Sned1, Mmus\Col28a1, Mmus\Ltbp3, Mmus\Dlk1, Mmus\Scube3, Mmus\Thbd, Mmus\Crb2, Mmus\Ltbp4, Mmus\Scube2, Mmus\Fbln7, Mmus\Jag2, Mmus\Egfl7, Mmus\Fbn1, Mmus\Hmcn2, Mmus\Egfem1, Mmus\Matn3, Mmus\Svep1, Mmus\Cd248" "Hsap\NOTCH2NL, Hsap\COL14A1, Hsap\TDGF1, Hsap\COL22A1, Hsap\THBD, Hsap\JAG1, Hsap\SNED1, Hsap\FBLN5, Hsap\DLL3, Hsap\DLK1, Hsap\SCUBE3, Hsap\CD248, Hsap\DLK2, Hsap\HABP2, Hsap\CLEC14A, Hsap\FBLN7, Hsap\DLL4, Hsap\LTBP3, Hsap\MATN3, Hsap\VWCE, Hsap\EGFL7, Hsap\EYS, Hsap\HGFAC, Hsap\SVEP1, Hsap\SCUBE2, Hsap\LOC100996717, Hsap\CRB2, Hsap\CFC1B, Hsap\CFC1, Hsap\LTBP1, Hsap\JAG2, Hsap\SCUBE1, Hsap\VWA1, Hsap\F12, Hsap\GAS6, Hsap\CD93" "viable,fertile" FBgn0013767 Crz Corazonin http://flybase.org/reports/FBgn0013767 - protein_coding_gene corazonin receptor binding ; GO:0071858 | inferred from physical interaction with CrzR neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity with UniProtKB:P11496 neuropeptide hormone activity ; GO:0005184 | traceable author statement neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay cellular response to ethanol ; GO:0071361 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern acetaldehyde metabolic process ; GO:0006117 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | traceable author statement behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype positive regulation of heart contraction ; GO:0045823 | inferred from sequence or structural similarity with UniProtKB:P11496 extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "COR, Cora, Drm-COR, Dm-Crz, CG3302, Crz, crz, cor, CRZ, CORZ, Corazonin" IPR020190:Procorazonin CG3302 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | stage 17 EW3 neuron

"viable,chemical resistant" FBgn0039795 Spn100A Serpin 100A http://flybase.org/reports/FBgn0039795 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 extracellular space ; GO:0005615 | inferred from sequence model "Spn100A, CG1342, Spn100" "IPR000215:Serpin family, IPR023796:Serpin domain" CG1342 11-Aug-17 DroID_v2017_08 "Drer\serpinh2, Drer\serpinh1b, Drer\serpinb1l1, Drer\zgc:173729, Drer\serpinb1l3, Drer\serpinb1l4, Drer\serpinb1l2, Drer\serpinc1, Drer\serpine2, Drer\serpinb1, Drer\serpine1, Drer\serpine3, Drer\serpina10a, Drer\si:ch1073-416d2.3, Drer\serpinh1a" - - - "Mmus\Serpinb10, Mmus\Serpine2, Mmus\Serpinb9e, Mmus\Serpine3, Mmus\Serpinb9c, Mmus\Serpinb6b, Mmus\Serpinb3b, Mmus\Serpinb13, Mmus\Serpinb9b, Mmus\Serpinb6c, Mmus\Serpinb3d, Mmus\Serpinb6d, Mmus\Serpinb3c, Mmus\Serpinb5, Mmus\Serpinb9, Mmus\Serpinb1c, Mmus\Serpinb8, Mmus\Serpinb9d, Mmus\Serpinb9f, Mmus\Serpina10, Mmus\Serpinc1, Mmus\Serpinb11, Mmus\Serpinb2, Mmus\Serpinb1a, Mmus\Serpinb12, Mmus\Serpinb1b, Mmus\Serpine1, Mmus\Serpinh1, Mmus\Serpinb6a, Mmus\Serpinb9g, Mmus\Serping1, Mmus\Gm11397, Mmus\Serpinb3a, Mmus\Serpinb6e" "Hsap\SERPINB6, Hsap\SERPINB1, Hsap\SERPINE3, Hsap\SERPINB4, Hsap\SERPINB8, Hsap\SERPINE1, Hsap\SERPINE2, Hsap\SERPINB12, Hsap\SERPINB2, Hsap\SERPINB10, Hsap\SERPINB11, Hsap\SERPINB9, Hsap\HMSD, Hsap\SERPINC1, Hsap\SERPINH1, Hsap\SERPINB3, Hsap\SERPINB13, Hsap\SERPINB5, Hsap\SERPINA10, Hsap\SERPING1" viable FBgn0039302 Nup358 Nucleoporin 358kD http://flybase.org/reports/FBgn0039302 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 Ran GTPase binding ; GO:0008536 | inferred from biological aspect of ancestor with PANTHER:PTN000566730 GTPase activator activity ; GO:0005096 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000566604 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 positive regulation of mitotic centrosome separation ; GO:0046604 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 spindle organization ; GO:0007051 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 NLS-bearing protein import into nucleus ; GO:0006607 | inferred from mutant phenotype protein import into nucleus ; GO:0006606 | inferred from mutant phenotype G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000566604 "CG11856, Nup358, RanBP2, nup358, Q9VBU7_DROME, NUP358" "IPR000156:Ran binding domain, IPR001876:Zinc finger, RanBP2-type, IPR011990:Tetratricopeptide-like helical domain, IPR011993:PH domain-like, IPR013026:Tetratricopeptide repeat-containing domain" CG11856 11-Aug-17 DroID_v2017_08 "Drer\ppie, Drer\ppih, Drer\LOC100333141, Drer\ppil6, Drer\ppiaa, Drer\ppig, Drer\si:ch1073-55a19.2, Drer\nktr, Drer\ppid, Drer\ppib, Drer\ranbp1, Drer\ppiab" "Scer\NUP2, Scer\YRB2, Scer\YRB1" "Cele\cyn-11, Cele\cyn-5, Cele\cyn-2, Cele\cyn-6, Cele\cyn-1, Cele\cyn-3, Cele\cyn-8, Cele\npp-9, Cele\cyn-9" "Xtro\ppih, Xtro\ppid, Xtro\ppia, Xtro\ppie, Xtro\ranbp2, Xtro\nktr, Xtro\ranbp1, Xtro\ppib, Xtro\ppil6, Xtro\ppic" "Mmus\Ppil6, Mmus\Ppif, Mmus\Ppid, Mmus\Ppia, Mmus\Ppig, Mmus\Nktr, Mmus\Ppie, Mmus\Ranbp1, Mmus\Ppic, Mmus\Ppih, Mmus\Ppib, Mmus\Ranbp2" "Hsap\PPIAL4C, Hsap\LOC105371242, Hsap\PPIF, Hsap\RGPD5, Hsap\RANBP1, Hsap\PPIA, Hsap\RGPD6, Hsap\RANBP2, Hsap\PPIB, Hsap\NKTR, Hsap\PPIAL4A, Hsap\RGPD3, Hsap\RGPD1, Hsap\PPIE, Hsap\RGPD2, Hsap\PPID, Hsap\RGPD8, Hsap\PPIL6, Hsap\RGPD4, Hsap\PPIAL4D, Hsap\PPIG, Hsap\PPIAL4G, Hsap\PPIC, Hsap\PPIH" "visible,partially lethal - majority die,some die during pupal stage" "tormogen cell,mesothoracic tergum" DRSC14410 IE 2.253897358 -0.390207146 4.362557625 0.668485866 -0.346054226 1.22586238 FBgn0014943 anon-98Dd anon-98Dd http://flybase.org/reports/FBgn0014943 - gene - - - anon-98Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015785 Pla Plane http://flybase.org/reports/FBgn0015785 - gene - - - Pla - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" wing FBgn0005424 l(1)adl13 lethal (1) adl13 http://flybase.org/reports/FBgn0005424 - gene - - - "l(1)adl-13, l(1)adl13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,heat sensitive,lethal,phototaxis defective,locomotor behavior defective,behavior defective,some die during immature adult stage,recessive" FBgn0002894 mus208 mutagen-sensitive 208 http://flybase.org/reports/FBgn0002894 - gene - - - mus208 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,viable,fertile,maternal effect" FBgn0030318 rho-4 rhomboid-4 http://flybase.org/reports/FBgn0030318 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 serine-type peptidase activity ; GO:0008236 | inferred from mutant phenotype serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 proteolysis ; GO:0006508 | inferred from direct assay protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001117493 "Rho-4, Rho-related [10C6], CG1697, rho-4, rho 4, rho4, DmRho4" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR002610:Peptidase S54, rhomboid, IPR011992:EF-hand domain pair, IPR017213:Peptidase S54, rhomboid, metazoan, IPR022764:Peptidase S54, rhomboid domain" CG1697 11-Aug-17 DroID_v2017_08 "Drer\rhbdl1, Drer\rhbdl3, Drer\rhbdl2" - "Cele\rom-2, Cele\rom-1" Xtro\rhbdl2 "Mmus\Rhbdl1, Mmus\Rhbdl3, Mmus\Rhbdl2" "Hsap\RHBDL2, Hsap\RHBDL1, Hsap\RHBDL3" "viable,fertile" "wing,wing vein,ectopic" FBgn0019889 anon-42Ea anon-42Ea http://flybase.org/reports/FBgn0019889 - gene - - - anon-42Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0003209 raw raw http://flybase.org/reports/FBgn0003209 "FBgn0010627, FBgn0015377, FBgn0022218, FBgn0032063, FBgn0032064" protein_coding_gene - "germ-band shortening ; GO:0007390 | inferred from mutant phenotype dorsal closure ; GO:0007391 | non-traceable author statement regulation of JNK cascade ; GO:0046328 | non-traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype dorsal closure, elongation of leading edge cells ; GO:0007394 | traceable author statement hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype ectodermal digestive tract morphogenesis ; GO:0048567 | inferred from mutant phenotype gonad morphogenesis ; GO:0035262 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement autophagic cell death ; GO:0048102 | inferred from expression pattern negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with acal central nervous system development ; GO:0007417 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern regulation of Malpighian tubule diameter ; GO:0035297 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay "raw, cyr, l(2)06825, CG9321, l(2)k03514, CG12437, ensh" IPR015943:WD40/YVTN repeat-like-containing domain CG12437 11-Aug-17 DroID_v2017_08 - - Cele\olrn-1 - - Hsap\RNASEL " embryonic stage | stage 7 , embryonic stage | stage >=13 , adult stage | female , embryonic stage | stage 8-12 , adult stage | male , embryonic stage | 12-16hr , embryonic stage | stage 7-12 , embryonic stage | stage 17 , embryonic stage " " dorsal fold

, embryonic/larval midgut

, ventral neurogenic region

, embryonic central nervous system

, ventral furrow

, midgut primordium

, cephalic furrow

, midgut constriction 2

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,fully,rescuable maternal effect,visible,partially lethal - majority die,some die during pupal stage" "dorsal closure embryo,presumptive embryonic/larval peripheral nervous system,neuron,extended germ band embryo,axon,embryonic/first instar larval cuticle,ventral,dorsal,gonad,gonadal sheath proper primordium,germline cell,male germline cell,embryonic Malpighian tubule,embryonic/larval digestive system,embryonic epidermis,embryonic head,Malpighian tubule,presumptive embryonic/larval central nervous system,embryonic/larval midgut,midgut constriction,embryonic/larval salivary gland,embryonic/larval hindgut,denticle,dorsal hair,trichogen cell,mesothoracic tergum" DRSC03599 IE -0.63442445 -5.922431427 -0.558955585 -3.723967213 0.835753407 -0.938173639 FBgn0051642 CG31642 - http://flybase.org/reports/FBgn0051642 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 - - "CG5981, CG31642" "IPR000433:Zinc finger, ZZ-type" CG31642 11-Aug-17 DroID_v2017_08 Drer\kcmf1 - "Cele\ZK652.6, Cele\Y57G11B.1" Xtro\kcmf1 Mmus\Kcmf1 Hsap\KCMF1 FBgn0028926 NC2beta Negative Cofactor 2beta http://flybase.org/reports/FBgn0028926 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription factor binding ; GO:0008134 | inferred from physical interaction with NC2α protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W2E3 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from physical interaction with NC2α" "histone acetylation ; GO:0016573 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay nucleosome mobilization ; GO:0042766 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from physical interaction with Ada2a "NC2beta, dDr1, Dr1, BG:DS00929.3, dNC2, CG4185, Nc2b, NC2 beta" "IPR003958:Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072:Histone-fold" CG4185 11-Aug-17 DroID_v2017_08 Drer\dr1 Scer\NCB2 Cele\dro-1 Xtro\dr1 Mmus\Dr1 Hsap\DR1 viable FBgn0019873 anon-92Ef anon-92Ef http://flybase.org/reports/FBgn0019873 - gene - - - anon-92Ef - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010333 Rac1 Rac1 http://flybase.org/reports/FBgn0010333 FBgn0014012 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from genetic interaction with mbc protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z7T0 protein kinase binding ; GO:0019901 | inferred from physical interaction with Pak3 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | traceable author statement GTPase activating protein binding ; GO:0032794 | inferred from physical interaction with RacGAP84C protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VF87 GTPase activity ; GO:0003924 | inferred from direct assay GTPase activity ; GO:0003924 | inferred from genetic interaction with cv-c GTPase activity ; GO:0003924 | non-traceable author statement" "small GTPase mediated signal transduction=0007264 |... electronic annotation with InterPro:IPR001806, InterPro:IPR003578 .. synapse assembly=0051963 |... nephrocyte filtration=0097206 |... positive .. axon guidance=1902669 |... ventral cord development=0007419 |... cellular response to DNA damage stimulus=0006974 |... actin cytoskeleton organization=0030036 | border follicle cell migration=0007298 |... hemocyte development=0007516 |... embryonic anterior midgut (ectodermal) morphogenesis=0048615 |... motor neuron axon guidance=0008045 |... JNK cascade=0007254 | .. locomotor rhythm=1904059 |... JNK cascade=0007254 |... axonal fasciculation=0007413 |... axon guidance=0007411 |...inferred from with Sra-1 establishment of tissue polarity=0007164 | .. axonogenesis=0050770 |... with LIMK1 adherens junction maintenance=0034334 |... head involution=0008258 |... negative .. lamellipodium assembly=0010593 |... myoblast fusion=0007520 | ovarian follicle cell development=0030707 | encapsulation of foreign target=0035010 |... .. dendrite morphogenesis=0048814 |...inferred from with Fmr1 positive .. filopodium assembly=0051491 |... rhabdomere development=0042052 |...inferred from with ninaE open tracheal system development=0007424 |... with Rac2 establishment of ommatidial planar polarity=0042067 | phagocytosis=0006909 |... mesodermal cell migration=0008078 |... dorsal closure, spreading of leading edge cells=0007395 |... actin filament organization=0007015 |... axon midline choice point recognition=0016199 |... with Sos dorsal closure=0007391 | .. hemocyte differentiation=0045610 |... dorsal closure=0007391 |... open tracheal system development=0007424 |... tracheal outgrowth, open tracheal system=0007426 |... with Rac2 muscle fiber development=0048747 |... immune response-regulating cell surface receptor signaling pathway .. phagocytosis=0002433 |... cortical actin cytoskeleton organization=0030866 |... morphogenesis of larval imaginal disc epithelium=0016335 | germ-band shortening=0007390 |... hemocyte migration=0035099 |...inferred from with Rac2 actin filament bundle assembly=0051017 |... lamellipodium assembly=0030032 |... axon guidance=0007411 |...inferred from with sli dorsal closure, elongation of leading edge cells=0007394 |... actin cytoskeleton reorganization=0031532 |... with Rac2, Mtl actin filament organization=0007015 |... with Pak3 dendrite morphogenesis=0048813 | axon guidance=0007411 |... peripheral nervous system development=0007422 |... neuron projection morphogenesis=0048812 |... salivary gland morphogenesis=0007435 |... neuron projection development=0031175 |... actin cytoskeleton organization=0030036 |... glial cell migration=0008347 |... cell morphogenesis=0000902 |... myoblast proliferation=0051450 |... cell-cell junction organization=0045216 | positive .. wound healing=0090303 |... with Rac2, Mtl dorsal appendage formation=0046843 |... cell competition in a multicellular organism=0035212 |... hemocyte migration=0035099 |... .. cell cycle=0051726 |... dendrite development=0016358 |... dorsal closure, amnioserosa morphology change=0046664 |... positive .. axon extension=0045773 |... with DAAM dorsal closure, amnioserosa morphology change=0046664 | melanotic encapsulation of foreign target=0035011 |... imaginal disc-derived wing hair site selection=0035320 |... .. digestive tract left/right asymmetry=0071907 |... cell proliferation=0008283 |... with tum sensory perception of touch=0050975 |... positive .. cell-matrix adhesion=0001954 |... activation of protein kinase activity=0032147 |... positive .. protein serine/threonine kinase activity=0071902 |... muscle attachment=0016203 |... with Rac2 .. synapse organization=0050807 |...inferred from with Sra-1 memory=0007613 |... myoblast fusion=0007520 |... microtubule-based process=0007017 | axon extension=0048675 |... mutant phenotype" extrinsic component of plasma membrane ; GO:0019897 | inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay ruffle ; GO:0001726 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay "Drac, rac1, DmRAC1, Rac, Drac1, GTPase Rac1, DRac1, Rac GTPase, rac, dRac1, D-Rac 1, Dm Rac1, dRac, DracA, DRac, RacA, D-Rac, D-Rac1, DRacA, Drac1a, Dmrac1, CG2248, Rac1, DmRAC, Rac-1, RAC1, 2248, P40792, Rac3, drac1" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR003578:Small GTPase superfamily, Rho type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2248 11-Aug-17 DroID_v2017_08 "Drer\LOC100331257, Drer\rhoga, Drer\si:ch211-133l11.10, Drer\rnd2, Drer\rhov, Drer\rhoh, Drer\rac3a, Drer\si:dkey-263f15.2, Drer\rnd3a, Drer\rhogd, Drer\rnd1a, Drer\rnd1b, Drer\LOC100537765, Drer\cdc42l, Drer\rac1l, Drer\rac3b, Drer\rhoj, Drer\cdc42l2, Drer\rhoab, Drer\rhogc, Drer\rhobtb2a, Drer\rhoq, Drer\cdc42, Drer\rhoaa, Drer\si:dkey-6b12.5, Drer\rhof, Drer\rhocb, Drer\rhobtb1, Drer\rhobtb2b, Drer\rhoua, Drer\rnd3b, Drer\rhogb, Drer\rhoca, Drer\rhoac, Drer\rac1a, Drer\rac1b, Drer\rhoub, Drer\rac2" "Scer\RHO4, Scer\RHO5, Scer\RHO1, Scer\RHO3, Scer\CDC42, Scer\RHO2" "Cele\rac-2, Cele\cdc-42, Cele\Y71H2AM.12, Cele\ced-10, Cele\mig-2" "Xtro\rnd1, Xtro\rhoj, Xtro\rhobtb2, Xtro\rhou, Xtro\rnd3, Xtro\rhoa.2, Xtro\rac1, Xtro\rhobtb1, Xtro\rhobtb3, Xtro\rhob, Xtro\rhov, Xtro\rhof, Xtro\cdc42, Xtro\rhoc, Xtro\rac2, Xtro\rhoa" "Mmus\4930544G11Rik, Mmus\Rhobtb1, Mmus\Rhou, Mmus\Rhoq, Mmus\Rhog, Mmus\Rac1, Mmus\Rac3, Mmus\Rhoj, Mmus\Rhobtb3, Mmus\Rhod, Mmus\Rhob, Mmus\Rhoa, Mmus\Rhoh, Mmus\Rac2, Mmus\Rhobtb2, Mmus\Rhof, Mmus\Rhoc, Mmus\Cdc42, Mmus\Rnd3, Mmus\Rhov, Mmus\Rnd1, Mmus\Rnd2" "Hsap\RHOC, Hsap\RHOU, Hsap\RHOQ, Hsap\RHOBTB1, Hsap\RND3, Hsap\RHOD, Hsap\RHOA, Hsap\RHOBTB2, Hsap\RHOB, Hsap\RHOV, Hsap\RHOH, Hsap\RAC3, Hsap\RHOG, Hsap\RND2, Hsap\RAC1, Hsap\CDC42, Hsap\RHOF, Hsap\RHOBTB3, Hsap\RND1, Hsap\RHOJ, Hsap\RAC2" " embryonic stage , embryonic stage | stage 10-12 , embryonic stage | blastoderm , embryonic stage -- adult stage " "

ubiquitous , somatic mesoderm

, embryonic/larval digestive system

, embryonic central nervous system

" "lethal,visible,planar polarity defective,wild-type,neuroanatomy defective,somatic clone,dominant,immune response defective,male semi-sterile,cell shape defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable,developmental rate defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,oxidative stress response defective,starvation stress response defective,stress response defective,touch sensitivity defective,cell death defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,neurophysiology defective,size defective,cell polarity defective,female,heat sensitive,cell migration defective,chemical sensitive,chemical resistant" "embryonic/larval pericardial cell,dorsal closure embryo,embryonic/first instar larval cuticle,border follicle cell,ommatidium,eye,interommatidial bristle,photoreceptor,pigment cell,photoreceptor cell,adult mushroom body,dendritic arborizing neuron,dorsal multidendritic neuron ddaC,peripheral glial cell,somatic clone,LNv neuron,ventral adult lateral neuron & commissure,axon & dorsal cluster neuron | somatic clone,presumptive embryonic salivary gland,lobe system of adult mushroom body,polar follicle cell,abdominal intersegmental nerve,axon,myoblast,photoreceptor cell & axonGMR.PF,primordium of embryonic/larval spiracle,macrophage,embryonic myoblast,dorsal,wing disc,wing,microchaeta & wingptc-559.1,anterior compartment,lamina,medulla,indirect flight muscle | larval stage,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,adult muscle precursor cell,A1-7 lateral longitudinal muscle 1,embryonic hemocyte,ventral nerve cord | embryonic stage,dorsal appendage,nurse follicle cell,eye disc,motor neuron,intersegmental nerve,ventral midline,medial longitudinal fascicle,abdominal segmental nerve,longitudinal connective,embryonic/larval midgut | embryonic stage,rhabdomereunspecified,rhabdomere & microvillusunspecified,rhabdomere & actin filamentunspecified,embryonic dorsal epidermis,hemocyte,lamellocyte,crystal cell,amnioserosa,embryonic epidermis,embryonic leading edge cell & actin filamenten-e16E,lamellipodiumen-e16E,embryonic segment,eye photoreceptor cell,presumptive embryonic/larval tracheal system,tracheal branch primordium,dorsal group branch precursor,dorsal trunk primordium,axon & dorsal cluster neuronato.3.6,aCC neuron,RP2 motor neuron,mesothoracic intersegmental nerve,metathoracic intersegmental nerve,prothoracic intersegmental nerve,dendritic spine & lobular plate tangential neuronDB331,neurite,giant axon,dendrite,rhabdomereGMR.PU,retina,embryonic/larval hindgut,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage1003.3,egg chamber,follicle cell,multidendritic neuron & dendrite | supernumerary477,multidendritic neuron & dendrite477,filopodium & dendrite109(2)80,macrochaeta,wing vein,sensillum campaniformium,melanotic mass,class I dendritic arborizing neuron,dendrite221,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage,dorsal cluster neuron | larval stage,filamentous actinppk.PG,posterior,embryonic/larval dorsal trunk | embryonic stage,embryonic/larval dorsal branch | embryonic stage,pCC neuron,dMP2 neuron,vMP2 neuron,midline crossing tract | embryonic stage 16,ventral nerve cord commissure | embryonic stage 16,embryonic/larval somatic muscle,midgut primordium,hindgut proper primordium,embryonic/larval trachea,actin filament & border follicle cell | somatic clone,germ band,dendrite | dorsal | embryonic stage60,VUM neuron,ventral nerve cord commissure,ventral nerve cord,embryonic/larval neuron,embryonic anterior Malpighian tubule,antennal lobe,antennal commissure,denticle,ectopic,longitudinal visceral muscle primordium,mesoderm | embryonic stage 8,germline cell | embryonic stage,anterior embryonic/larval midgut,muscle fiber | embryonic stage" DRSC08688 IE -0.532492871 -4.401186956 -0.816858829 -1.593446606 -0.517344632 -0.985812725 FBgn0002122 l(2)H lethal (2) Humphrey http://flybase.org/reports/FBgn0002122 - gene - - - l(2)H - - 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262378 mir-317 mir-317 stem loop http://flybase.org/reports/FBgn0262378 miRNA_gene - brain morphogenesis ; GO:0048854 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - "miR-317, dme-mir-317, mir-317, 317, MIR-317, CR42900, Mir-317, CR33621, dme-miR-317" - CR42900 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065136 l(3)SH116 lethal (3) SH116 http://flybase.org/reports/FBgn0065136 gene - - - "l(3)SH116, l(2)SH3 116" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040747 CG12853 - http://flybase.org/reports/FBgn0040747 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs26d12.y1, NEST:bs26d12, CG12853" - CG12853 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010431 mtrm matrimony http://flybase.org/reports/FBgn0010431 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype homologous chromosome segregation ; GO:0045143 | inferred from mutant phenotype regulation of meiotic cell cycle ; GO:0051445 | inferred from mutant phenotype cell cycle arrest ; GO:0007050 | inferred from mutant phenotype distributive segregation ; GO:0032837 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG18543, D52, anonD52, anon-D52, mtrm" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG18543 11-Aug-17 DroID_v2017_08 Drer\exoc7 Scer\EXO70 - Xtro\exoc7 Mmus\Exoc7 Hsap\EXOC7 "female fertile,meiotic cell cycle defective,dominant,female sterile,recessive,male fertile,lethal - all die before end of pupal stage,some die during pupal stage" "oocyte nucleus,oocyte & nuclear chromosome,cystoblast,karyosome,meiotic spindle66C-T2-10)" FBgn0060715 l(3)S069805 lethal (3) S069805 http://flybase.org/reports/FBgn0060715 gene - - - "0698/05, l(3)S069805" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0085359 CG34330 - http://flybase.org/reports/FBgn0085359 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG34330, CG33254" - CG34330 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,mesothoracic tergum" FBgn0040555 CG14371 - http://flybase.org/reports/FBgn0040555 protein_coding_gene - - - CG14371 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005450 l(1)v227 lethal (1) v227 http://flybase.org/reports/FBgn0005450 - gene - - - "l(1)227, l(1)v227" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069922 CG41129 - http://flybase.org/reports/FBgn0069922 protein_coding_gene - - - CG41129 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003619 Su(var)2-57 Suppressor of variegation 2-57 http://flybase.org/reports/FBgn0003619 - gene - - - Su(var)2-57 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016876 l(2)39DEa lethal (2) 39DEa http://flybase.org/reports/FBgn0016876 - gene - - - "A447, l(2)39DEa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037329 POLDIP2 "Polymerase (DNA-directed), delta interacting protein 2" http://flybase.org/reports/FBgn0037329 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR011722 - - "CG12162, POLDIP2" "IPR007474:ApaG domain, IPR011722:Hemimethylated DNA-binding domain" CG12162 11-Aug-17 DroID_v2017_08 "Drer\smtnl, Drer\fbxo3, Drer\poldip2" - Cele\tag-307 "Xtro\fbxo3, Xtro\poldip2" "Mmus\Poldip2, Mmus\Fbxo3" "Hsap\POLDIP2, Hsap\FBXO3" "viable,fertile" FBgn0001243 hypoC hypoactive C http://flybase.org/reports/FBgn0001243 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "hypoC, hypo C" - - 11-Aug-17 DroID_v2017_08 - - - - - - "hypoactive,optomotor response defective,courtship behavior defective,female,jumping defective,locomotor behavior defective,flight defective" embryonic/larval heart FBgn0038110 CG8031 - http://flybase.org/reports/FBgn0038110 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of microtubule-based process ; GO:0032886 | inferred from sequence or structural similarity with HGNC:14014 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:14014 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:14014 "CG8031, dMEMO" IPR002737:MEMO1 family CG8031 11-Aug-17 DroID_v2017_08 Drer\memo1 Scer\MHO1 Cele\memo-1 Xtro\memo1 Mmus\Memo1 Hsap\MEMO1 viable DRSC16364 K -1.171711852 -0.004898056 -0.218406513 0.423208207 -1.981113688 -0.226154002 FBgn0028236 l(3)S003006 lethal (3) S003006 http://flybase.org/reports/FBgn0028236 gene - - - "30/6, 0030/06, l(3)S003006" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0264259 Roc1a::Roc1b - http://flybase.org/reports/FBgn0264259 engineered_fusion_gene - - - Roc1a::Roc1b - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037970 GC2 Glutamate Carrier 2 http://flybase.org/reports/FBgn0037970 protein_coding_gene high-affinity glutamate transmembrane transporter activity ; GO:0005314 | inferred from direct assay mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 L-glutamate transmembrane transport ; GO:0089711 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with MGI:MGI:1919053 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640304 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG12201, DmGC2, GC2" "IPR002067:Mitochondrial carrier protein, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG12201 11-Aug-17 DroID_v2017_08 "Drer\slc25a22, Drer\slc25a18, Drer\zgc:92113, Drer\si:ch73-219d10.1, Drer\slc25a12, Drer\si:dkey-201c1.2" "Scer\AGC1, Scer\GGC1" "Cele\F55G1.5, Cele\F20D1.9" "Xtro\slc25a12, Xtro\slc25a13, Xtro\slc25a22, Xtro\slc25a18" "Mmus\Slc25a22, Mmus\Slc25a12, Mmus\Slc25a13, Mmus\Slc25a18" "Hsap\SLC25A13, Hsap\SLC25A12, Hsap\SLC25A18, Hsap\SLC25A22" viable FBgn0262530 CG43084 - http://flybase.org/reports/FBgn0262530 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43084 - CG43084 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034588 CG9394 - http://flybase.org/reports/FBgn0034588 protein_coding_gene starch binding ; GO:2001070 | inferred from electronic annotation with InterPro:IPR002044 glycerophosphodiester phosphodiesterase activity ; GO:0008889 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 glycerophosphocholine phosphodiesterase activity ; GO:0047389 | inferred from biological aspect of ancestor with PANTHER:PTN001120996 glycerophospholipid catabolic process ; GO:0046475 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 cellular phosphate ion homeostasis ; GO:0030643 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 - "anon-EST:Posey227, CG9394" "IPR030395:Glycerophosphodiester phosphodiesterase domain, IPR002044:Carbohydrate binding module family 20, IPR013784:Carbohydrate-binding-like fold, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR033506:Glycerophosphodiester phosphodiesterase Gde1, IPR013783:Immunoglobulin-like fold" CG9394 11-Aug-17 DroID_v2017_08 Drer\gpcpd1 "Scer\PHO81, Scer\GDE1" "Cele\gpcp-1, Cele\gpcp-2" - Mmus\Gpcpd1 Hsap\GPCPD1 viable DRSC04550 E -0.65647632 0.922836519 1.663316794 0.196380732 -0.807330223 0.767993432 FBgn0020901 Su(osk)B11 Suppressor of oskar B11 http://flybase.org/reports/FBgn0020901 - gene - - - "B11, Su(osk)B11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037666 CR16735 - http://flybase.org/reports/FBgn0037666 pseudogene_attribute - - - "CR16735, CG16735" - CR16735 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0262866 S6kII Ribosomal protein S6 kinase II http://flybase.org/reports/FBgn0262866 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR016239 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement ribosomal protein S6 kinase activity ; GO:0004711 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with rl ribosomal protein S6 kinase activity ; GO:0004711 | inferred from direct assay" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR016239 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement operant conditioning ; GO:0035106 | inferred from mutant phenotype operant conditioning ; GO:0035106 | traceable author statement negative regulation of compound eye cone cell fate specification ; GO:0042683 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype regulation of neuromuscular junction development ; GO:1904396 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype associative learning ; GO:0008306 | traceable author statement associative learning ; GO:0008306 | inferred from mutant phenotype negative regulation of protein import into nucleus ; GO:0042308 | inferred from direct assay negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Raf inferred from genetic interaction with Ras85D locomotor rhythm ; GO:0045475 | inferred from mutant phenotype negative regulation of pigment cell differentiation ; GO:0050941 | inferred from mutant phenotype negative regulation of photoreceptor cell differentiation ; GO:0046533 | inferred from mutant phenotype" perikaryon ; GO:0043204 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay presynapse ; GO:0098793 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 "S6KII, CG17596, S6kII, rsk2, dRSK, RSK, ign, Rsk, rsk" "IPR016239:Ribosomal protein S6 kinase II, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal" CG17596 11-Aug-17 DroID_v2017_08 "Drer\rps6ka4, Drer\akt3a, Drer\sgk2b, Drer\sgk3, Drer\rps6kb1b, Drer\sgk1, Drer\rps6ka5, Drer\rps6ka3b, Drer\rps6ka1, Drer\akt3b, Drer\rps6ka2, Drer\akt2, Drer\LOC100331306, Drer\rps6kb1a, Drer\stk32a, Drer\sgk2a, Drer\si:ch211-195b13.1, Drer\rps6ka3a, Drer\rps6kal" "Scer\YPK1, Scer\YPK2, Scer\SCH9, Scer\CTK1, Scer\YPK3" "Cele\akt-1, Cele\rskn-2, Cele\rsks-1, Cele\akt-2, Cele\sgk-1, Cele\rskn-1" "Xtro\rps6ka4, Xtro\rps6ka6, Xtro\rps6kb1, Xtro\sgk2, Xtro\rps6ka1, Xtro\rps6ka2, Xtro\rps6ka3, Xtro\akt2, Xtro\stk32a, Xtro\akt1, Xtro\sgk1" "Mmus\Akt3, Mmus\Rps6kb2, Mmus\Rps6ka3, Mmus\Sgk2, Mmus\Rps6ka2, Mmus\Akt2, Mmus\Rps6ka4, Mmus\Rps6ka6, Mmus\Sgk3, Mmus\Rps6ka1, Mmus\Sgk1, Mmus\Stk32c, Mmus\Rps6ka5, Mmus\Stk32b, Mmus\Rps6kb1, Mmus\Akt1, Mmus\Stk32a" "Hsap\SGK3, Hsap\STK32A, Hsap\AKT3, Hsap\RPS6KB2, Hsap\AKT2, Hsap\RPS6KA1, Hsap\SGK1, Hsap\STK32C, Hsap\RPS6KA6, Hsap\RPS6KA5, Hsap\RPS6KA2, Hsap\AKT1, Hsap\RPS6KA4, Hsap\RPS6KA3, Hsap\STK32B, Hsap\SGK2, Hsap\RPS6KB1" DRSC20645 I 2.478065299 0.828545961 0.413457051 0.311762505 0.388344985 -0.031134091 FBgn0025745 l(3)tb lethal (3) tumorous brain http://flybase.org/reports/FBgn0025745 - gene - - - l(3)tb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "optic lobe,wing disc" FBgn0032290 CG6443 - http://flybase.org/reports/FBgn0032290 protein_coding_gene - mitotic DNA replication termination ; GO:1902979 | inferred from electronic annotation with InterPro:IPR006735 site-specific DNA replication termination at RTS1 barrier ; GO:0071171 | inferred from biological aspect of ancestor with PANTHER:PTN000299506 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000299506 CG6443 "IPR006735:Replication termination factor 2, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027799:Replication termination factor 2, RING-finger" CG6443 11-Aug-17 DroID_v2017_08 Drer\rtfdc1 - Cele\tads-1 Xtro\rtfdc1 Mmus\Rtfdc1 Hsap\RTFDC1 "viable,visible" mesothoracic tergum DRSC02958 EK 0.472332685 0.740737273 1.593101841 0.994644068 1.786021454 0.77370707 FBgn0060453 l(3)S119601b lethal (3) S119601b http://flybase.org/reports/FBgn0060453 gene - - - "1196/01, l(3)S119601b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0085636 CG41373 - http://flybase.org/reports/FBgn0085636 protein_coding_gene - - - CG41373 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267222 CR45662 - http://flybase.org/reports/FBgn0267222 non_protein_coding_gene - - - CR45662 - CR45662 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070028 BG00372 BG00372 http://flybase.org/reports/FBgn0070028 gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - BG00372 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,behavior defective,recessive" FBgn0278599 CR46269 - http://flybase.org/reports/FBgn0278599 non_protein_coding_gene - - - CR46269 - CR46269 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264415 FCE-H - http://flybase.org/reports/FBgn0264415 gene - - - FCE-H - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg chamber,somatic clone" FBgn0030462 CG15742 - http://flybase.org/reports/FBgn0030462 protein_coding_gene - - - CG15742 - CG15742 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030586 CG12539 - http://flybase.org/reports/FBgn0030586 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG12539, Dm GMCiota2" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG12539 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0015996 l(3)03884 lethal (3) 03884 http://flybase.org/reports/FBgn0015996 - gene - - - "l(3)3884, l(3)03884" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011652 Mads-4 Mads-4 http://flybase.org/reports/FBgn0011652 - gene - - - Mads-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021959 l(2)k10209 lethal (2) k10209 http://flybase.org/reports/FBgn0021959 - gene - - - l(2)k10209 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible" "leg,metathoracic femur" FBgn0036170 CG11714 - http://flybase.org/reports/FBgn0036170 protein_coding_gene - - - "CG11714, CG33047" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain" CG11714 11-Aug-17 DroID_v2017_08 "Drer\btbd6a, Drer\klhl41a, Drer\btbd2, Drer\btbd17b, Drer\btbd6b, Drer\btbd3b, Drer\btbd3a" - - "Xtro\btbd2, Xtro\btbd1, Xtro\btbd3, Xtro\btbd6" "Mmus\Btbd1, Mmus\Btbd3, Mmus\Btbd17, Mmus\Btbd6, Mmus\Btbd2" "Hsap\BTBD2, Hsap\BTBD17, Hsap\BTBD6, Hsap\BTBD3, Hsap\BTBD1" "viable,fertile" FBgn0016765 anon-17Cb anon-17Cb http://flybase.org/reports/FBgn0016765 - gene - - - "C2, anon-17Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | early , adult stage | female " FBgn0263520 mir-4945 mir-4945 stem loop http://flybase.org/reports/FBgn0263520 miRNA_gene - - - "mir-4945, dme-mir-4945, CR43505" - CR43505 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002879 mus102 mutagen-sensitive 102 http://flybase.org/reports/FBgn0002879 - gene - - - "mus 102, mus-102, mus(1)102, mus102" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,female fertile,reduced,meiotic cell cycle defective,mitotic cell cycle defective,radiation sensitive" mitosis & nuclear chromosome FBgn0004020 wobB wobbly B http://flybase.org/reports/FBgn0004020 - gene - - - wobB - - 11-Aug-17 DroID_v2017_08 - - - - - - uncoordinated FBgn0051788 CG31788 - http://flybase.org/reports/FBgn0051788 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31788 - CG31788 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC01630 IE 2.673435216 0.176133719 -2.295411984 0.04372888 -0.192691856 -0.417913717 FBgn0034415 CG15116 - http://flybase.org/reports/FBgn0034415 protein_coding_gene glutathione peroxidase activity ; GO:0004602 | inferred from electronic annotation with InterPro:IPR000889 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR000889 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000889 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG15116, GPx-like" "IPR000889:Glutathione peroxidase, IPR012336:Thioredoxin-like fold" CG15116 11-Aug-17 DroID_v2017_08 "Drer\gpx4b, Drer\gpx7, Drer\gpx1a, Drer\gpx3, Drer\gpx1b, Drer\si:ch73-111m19.2, Drer\gpx4a, Drer\gpx8" "Scer\GPX1, Scer\HYR1, Scer\GPX2" "Cele\gpx-8, Cele\gpx-6, Cele\gpx-2, Cele\gpx-1, Cele\gpx-7" "Xtro\gpx7, Xtro\gpx3, Xtro\gpx1" "Mmus\Gpx6, Mmus\Gpx7, Mmus\Gpx3, Mmus\Gpx4, Mmus\Gpx2, Mmus\Gpx1, Mmus\Gpx5, Mmus\Gpx8" "Hsap\GPX3, Hsap\GPX4, Hsap\GPX6, Hsap\GPX1, Hsap\GPX2, Hsap\GPX7, Hsap\GPX8, Hsap\GPX5" "viable,visible" trichogen cell FBgn0014847 Egfr::tor Egfr::tor http://flybase.org/reports/FBgn0014847 - engineered_fusion_gene - - - "Egfr::tor, EGFR" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,heat sensitive,decreased cell death,increased cell size,cell death defective,somatic clone,neuroanatomy defective" "eye,mystery cell,primary pigment cell,cone cell,photoreceptor cell R7,ganglionic branch 1 | embryonic stage,eye disc,photoreceptor cell,morphogenetic furrow,photoreceptor,cell autonomous,ectopic,somatic clone,cell non-autonomous,ommatidial precursor cluster,wing,embryonic segment,supernumerary,dorsocentral bristle,enterocyte,adult gut,midgut,embryonic/larval brain | third instar larval stage,embryonic/larval neuroblast,ectopic | third instar larval stage" FBgn0041581 AttB Attacin-B http://flybase.org/reports/FBgn0041581 protein_coding_gene - humoral immune response ; GO:0006959 | inferred from expression pattern antibacterial humoral response ; GO:0019731 | inferred from sequence or structural similarity with AttA inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | traceable author statement "AttB, att, AttBn, Att, AttB1, CG18372, AttB2, attB, att B1, Att B, Attb" "IPR005520:Attacin, N-terminal, IPR005521:Attacin, C-terminal" CG18372 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001159 gustB gustatory-defective B http://flybase.org/reports/FBgn0001159 - gene - - - "gust[x5], gusF, gustB" - - 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,recessive" labellar taste bristle FBgn0052639 CG32639 - http://flybase.org/reports/FBgn0052639 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32639 - CG32639 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC18972 E -0.405936113 0.428500835 -1.517566218 0.802459952 0.813863658 -0.526476637 FBgn0267734 CR46065 - http://flybase.org/reports/FBgn0267734 non_protein_coding_gene - - - "CR46065, Mgn00290" - CR46065 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085433 CG34404 - http://flybase.org/reports/FBgn0085433 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from sequence or structural similarity with HGNC:6935 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6935 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:6935 "CG34404, CG18496, anon-FF, CG6156" "IPR019536:Usher syndrome type-1C protein-binding protein 1, PDZ domain" CG34404 11-Aug-17 DroID_v2017_08 "Drer\mcc, Drer\ushbp1, Drer\LOC795364" - Cele\C04E7.3 Xtro\mcc "Mmus\Ushbp1, Mmus\Mcc" "Hsap\USHBP1, Hsap\MCC" viable FBgn0065743 l(2)SH0521 lethal (2) SH0521 http://flybase.org/reports/FBgn0065743 gene - - - "l(2)SH0521, l(2)SH2 0521" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083998 CG41431 - http://flybase.org/reports/FBgn0083998 protein_coding_gene - - - CG41431 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020285 l(3)06266 lethal (3) 06266 http://flybase.org/reports/FBgn0020285 - gene - - - l(3)06266 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034647 pirk poor Imd response upon knock-in http://flybase.org/reports/FBgn0034647 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with imd receptor binding ; GO:0005102 | inferred from physical interaction with PGRP-LE inferred from physical interaction with PGRP-LC negative regulation of immune response ; GO:0050777 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype negative regulation of peptidoglycan recognition protein signaling pathway ; GO:0061060 | inferred from mutant phenotype response to symbiotic bacterium ; GO:0009609 | inferred from mutant phenotype - "BcDNA:SD16010, pirk, CG15678, pims, Rudra, Pirk, Pims, rudra, PIRK, PIMS" - CG15678 11-Aug-17 DroID_v2017_08 - - - - - - "immune response defective,viable,fertile,short lived" FBgn0035282 CNMa CNMamide http://flybase.org/reports/FBgn0035282 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay extracellular space ; GO:0005615 | inferred by curator from GO:0005184 "CG13936, CNMa" - CG13936 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0267691 CR46027 - http://flybase.org/reports/FBgn0267691 pseudogene_attribute - - - "CR46027, mdcds_23070" - CR46027 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010520 Bka Bekka http://flybase.org/reports/FBgn0010520 "FBgn0032155, FBgn0063059" protein_coding_gene - "cellular response to starvation ; GO:0009267 | inferred from expression pattern maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000275999 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000275999 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000275999 "CG4539, mip, l(2)02695, BcDNA:RE14949, Bka" "IPR006984:rRNA-processing protein Fcf1/Utp23, IPR029060:PIN domain-like, IPR002716:PIN domain" CG4539 11-Aug-17 DroID_v2017_08 Drer\fcf1 Scer\FCF1 Cele\F30A10.9 Xtro\fcf1 Mmus\Fcf1 Hsap\FCF1 "lethal,recessive,viable" FBgn0065874 l(2)SH0246 lethal (2) SH0246 http://flybase.org/reports/FBgn0065874 gene - - - l(2)SH0246 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051802 CG31802 - http://flybase.org/reports/FBgn0051802 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity "CG15158, BcDNA:AT22559, CG31802" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG31802 11-Aug-17 DroID_v2017_08 "Drer\cetn2, Drer\cetn4, Drer\cetn3" Scer\CDC31 Cele\R08D7.5 "Xtro\cetn1, Xtro\cetn3, Xtro\cetn4" "Mmus\Cetn1, Mmus\Cetn4, Mmus\Cetn3, Mmus\Cetn2" "Hsap\CETN1, Hsap\CETN3, Hsap\CETN2" viable FBgn0083235 EP454 EP454 http://flybase.org/reports/FBgn0083235 gene - - - EP454 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022765 Scruffy Scruffy http://flybase.org/reports/FBgn0022765 - gene - - - "Scruffy, Scf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,viable,wild-type,lethal,recessive" "tergite,anterior" FBgn0034611 MFS16 Major Facilitator Superfamily Transporter 16 http://flybase.org/reports/FBgn0034611 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR000849 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000849, InterPro:IPR011701" "MFS16, CG10069" "IPR011701:Major facilitator superfamily, IPR000849:Sugar phosphate transporter, IPR020846:Major facilitator superfamily domain" CG10069 11-Aug-17 DroID_v2017_08 "Drer\slc37a4b, Drer\slc37a1, Drer\slc37a2" "Scer\YOL162W, Scer\YOL163W, Scer\THI73, Scer\TNA1, Scer\YCT1, Scer\SEO1" "Cele\Y19D10A.8, Cele\T11G6.3, Cele\T11G6.4, Cele\T10C6.6, Cele\T11G6.2" Xtro\slc37a2 "Mmus\Slc37a2, Mmus\Slc37a3, Mmus\Slc37a1" "Hsap\SLC37A3, Hsap\SLC37A2, Hsap\SLC37A1" "viable,fertile" FBgn0019732 l(1)A14 lethal (1) A14 http://flybase.org/reports/FBgn0019732 - gene - - - l(1)A14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085627 CG41346 - http://flybase.org/reports/FBgn0085627 protein_coding_gene - - - CG41346 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266775 CR45240 - http://flybase.org/reports/FBgn0266775 non_protein_coding_gene - - - CR45240 - CR45240 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028159 l(3)S041415 lethal (3) S041415 http://flybase.org/reports/FBgn0028159 gene - - - "0414/15, l(3)S041415" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0266521 stai stathmin http://flybase.org/reports/FBgn0266521 protein_coding_gene tubulin binding ; GO:0015631 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from sequence or structural similarity regulation of microtubule polymerization or depolymerization ; GO:0031110 | inferred from electronic annotation with InterPro:IPR000956 microtubule depolymerization ; GO:0007019 | inferred from biological aspect of ancestor with PANTHER:PTN000802387 germ cell migration ; GO:0008354 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype regulation of cytoskeleton organization ; GO:0051493 | inferred from biological aspect of ancestor with PANTHER:PTN000802387 neuron projection development ; GO:0031175 | inferred from biological aspect of ancestor with PANTHER:PTN000010206 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN000010206 neuromuscular junction ; GO:0031594 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "stai, rdt, rdtp, CG31641, CG5981, LD33989, BEST:LD33989, SCG10-like, D-stat" IPR000956:Stathmin family CG31641 11-Aug-17 DroID_v2017_08 "Drer\stmn2b, Drer\stmn4, Drer\stmn1a, Drer\stmn4l, Drer\stmn2a, Drer\stmn1b, Drer\stmn3" - - "Xtro\stmn1, Xtro\stmn3, Xtro\stmn4, Xtro\stmn2" "Mmus\Stmn4, Mmus\Stmn2, Mmus\Stmn3, Mmus\Stmn1" "Hsap\STMN2, Hsap\STMN3, Hsap\STMN1, Hsap\STMN4" FBgn0000370 crc cryptocephal http://flybase.org/reports/FBgn0000370 "FBgn0020511, FBgn0032941, FBtr0081512, FBpp0081040, FBtr0081513, FBpp0081041" protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity RNA polymerase II activating transcription factor binding ; GO:0001102 | inferred from physical interaction with EcR RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from mutant phenotype transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with protein_id:CAA43723.1 RNA polymerase II transcription coactivator activity ; GO:0001105 | inferred from mutant phenotype inferred from physical interaction with EcR" "response to starvation ; GO:0042594 | inferred from mutant phenotype molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype triglyceride metabolic process ; GO:0006641 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with protein_id:CAA43723.1 trehalose metabolic process ; GO:0005991 | inferred from mutant phenotype pupation ; GO:0035074 | inferred from mutant phenotype PERK-mediated unfolded protein response ; GO:0036499 | inferred from genetic interaction with Dad1 metamorphosis ; GO:0007552 | inferred from mutant phenotype protein N-linked glycosylation ; GO:0006487 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred by curator from GO:0001105,GO:0045944 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from direct assay" "CG8669, dATF-4, ATF-4, 929, l(2)crc, crc, ATF4/crc, Ire1, Atf4, ATF4, dATF4, DM6, Crc, atf4" IPR004827:Basic-leucine zipper domain CG8669 11-Aug-17 DroID_v2017_08 "Drer\atf4a, Drer\atf5a, Drer\atf4b, Drer\atf5b" Scer\MET4 "Cele\atfs-1, Cele\zip-3, Cele\atf-5" "Xtro\atf5, Xtro\atf4, Xtro\atf5.2" "Mmus\Atf4, Mmus\Atf5" "Hsap\ATF5, Hsap\ATF4" "starvation stress response defective,viable,fertile,partially lethal - majority die,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "pupal abdomen,adult head,ventral thoracic disc,anterior pupal spiracle,pupa,wing disc,cephalopharyngeal skeleton,wing,adult cuticle,leg,scutellum,scutellar bristle,haltere,adult thorax,dorsal" FBgn0015881 anon-48Aj anon-48Aj http://flybase.org/reports/FBgn0015881 - gene - - - "XII, anon-48Aj" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002362 l(3)87Ej lethal (3) 87Ej http://flybase.org/reports/FBgn0002362 - gene - - - "G5, l(3)G5, l(3)87Ej" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037248 srl spargel http://flybase.org/reports/FBgn0037248 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity ligand-dependent nuclear receptor transcription coactivator activity ; GO:0030374 | inferred from biological aspect of ancestor with PANTHER:PTN000399017 transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN000399017 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from biological aspect of ancestor with PANTHER:PTN000399017 "response to oxidative stress ; GO:0006979 | inferred from mutant phenotype negative regulation of insulin receptor signaling pathway ; GO:0046627 | inferred from mutant phenotype regulation of mitochondrion organization ; GO:0010821 | inferred from genetic interaction with Ets97D insulin receptor signaling pathway ; GO:0008286 | inferred from mutant phenotype tissue homeostasis ; GO:0001894 | inferred from mutant phenotype energy homeostasis ; GO:0097009 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000399017 positive regulation of sequence-specific DNA binding transcription factor activity ; GO:0051091 | inferred from biological aspect of ancestor with PANTHER:PTN000399017 positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype" nucleus ; GO:0005634 | colocalizes_with inferred from direct assay nuclear speck ; GO:0016607 | inferred from direct assay cytoplasm ; GO:0005737 | colocalizes_with inferred from direct assay "cg9809, dPGC, CG9809, PGC-1-alpha, CG 9809, dPGC-1, spargel, Srl, srl, Spargel, dPGC1, PGC-1, dPCG1alpha, PGC-1/srl" "IPR000504:RNA recognition motif domain, IPR034605:PGC-1" CG9809 11-Aug-17 DroID_v2017_08 "Drer\pprc1, Drer\ppargc1a, Drer\ppargc1b, Drer\si:dkey-93h22.8" - - "Xtro\pprc1, Xtro\ppargc1b, Xtro\ppargc1a" "Mmus\Ppargc1a, Mmus\Ppargc1b, Mmus\Pprc1" "Hsap\PPARGC1B, Hsap\PPRC1, Hsap\PPARGC1A" "small body,female sterile,developmental rate defective,wild-type,decreased cell size,cell autonomous,somatic clone,aging defective,short lived,long lived,fertile,RU486 conditional,viable" "fat body,lipid particle,mitochondrionda.G32,mitochondrial membraneda.G32,mitochondrionesg-05730B,mitochondrial membraneesg-05730B,adult hindgut,adult midgut" FBgn0266884 CR45345 - http://flybase.org/reports/FBgn0266884 non_protein_coding_gene - - - CR45345 - CR45345 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034866 Or59c Odorant receptor 59c http://flybase.org/reports/FBgn0034866 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 sensory perception of smell ; GO:0007608 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "Or59c, 59c, DOR120, 59E.2, CG17226" "IPR004117:Olfactory receptor, insect" CG17226 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263090 CR43358 - http://flybase.org/reports/FBgn0263090 non_protein_coding_gene - - - "CR43358, lincRNA.181" - CR43358 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031875 CG3430 - http://flybase.org/reports/FBgn0031875 protein_coding_gene chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000337082 sister chromatid cohesion ; GO:0007062 | inferred from biological aspect of ancestor with PANTHER:PTN000337082 DNA-dependent DNA replication ; GO:0006261 | inferred from biological aspect of ancestor with PANTHER:PTN000337082 MCM complex ; GO:0042555 | colocalizes_with inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000337082 CG3430 IPR019140:Mini-chromosome maintenance complex-binding protein CG3430 11-Aug-17 DroID_v2017_08 Drer\mcmbp - - Xtro\mcmbp Mmus\Mcmbp Hsap\MCMBP "viable,fertile" FBgn0000824 fs(1)K1563 female sterile (1) K1563 http://flybase.org/reports/FBgn0000824 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available fs(1)K1563 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile soma-dependent,female sterile,semidominant,heat sensitive,recessive,viable" "egg,heat sensitive,chorion,dorsal appendage" FBgn0260124 2L1296 - http://flybase.org/reports/FBgn0260124 gene - - - 2L1296 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "embryonic/larval epidermis,somatic clone" FBgn0061047 l(3)S023450 lethal (3) S023450 http://flybase.org/reports/FBgn0061047 gene - - - "0234/50, l(3)S023450" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0016880 l(2)39DEe lethal (2) 39DEe http://flybase.org/reports/FBgn0016880 - gene - - - "C704, l(2)39DEe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001442 l(1)7Cd lethal (1) 7Cd http://flybase.org/reports/FBgn0001442 - gene - - - l(1)7Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261584 CG42694 - http://flybase.org/reports/FBgn0261584 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 molecular_function ; GO:0003674 | no biological data available" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available CG42694 "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG42694 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026079 Nsun2 "NOP2-Sun domain family, member 2" http://flybase.org/reports/FBgn0026079 FBgn0029695 protein_coding_gene tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000516077 tRNA (cytosine-5-)-methyltransferase activity ; GO:0016428 | inferred from sequence or structural similarity with HGNC:25994 tRNA (cytosine-5-)-methyltransferase activity ; GO:0016428 | inferred from biological aspect of ancestor with PANTHER:PTN000516077 tRNA (cytosine-5-)-methyltransferase activity ; GO:0016428 | inferred from sequence or structural similarity with UniProtKB:Q08J23 short-term memory ; GO:0007614 | inferred from mutant phenotype RNA methylation ; GO:0001510 | inferred from sequence or structural similarity with HGNC:25994 tRNA methylation ; GO:0030488 | inferred from biological aspect of ancestor with PANTHER:PTN000516077 tRNA methylation ; GO:0030488 | inferred from sequence or structural similarity with UniProtKB:Q08J23 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q08J23 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000516077 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q08J23 "EG:EG0007.9, Nsun2, CG6133, dNsun2, NSun2" "IPR001678:SAM-dependent methyltransferase RsmB/NOP2-type, IPR018314:Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR023267:RNA (C5-cytosine) methyltransferase, IPR023270:tRNA (C5-cytosine) methyltransferase, NCL1" CG6133 11-Aug-17 DroID_v2017_08 "Drer\nsun4, Drer\nsun3, Drer\nsun2" Scer\NCL1 Cele\Y48G8AL.5 "Xtro\nsun2, Xtro\nsun4, Xtro\nsun3" "Mmus\Nsun3, Mmus\Nsun2, Mmus\Nsun4" "Hsap\NSUN4, Hsap\NSUN2, Hsap\NSUN3" "viable,male fertile,female semi-fertile,memory defective" DRSC18662 E 0.852001195 0.245123923 2.711656978 -0.433023994 0.794947508 -0.105578776 FBgn0060477 l(3)S111505b lethal (3) S111505b http://flybase.org/reports/FBgn0060477 gene - - - "1115/05, l(3)S111505b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0083310 E(smoDN)1419 Enhancer of smoDN 1419 http://flybase.org/reports/FBgn0083310 gene - - - E(smoDN)1419 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000660 fl fluted http://flybase.org/reports/FBgn0000660 - gene - - - fl - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0264891 CR44082 - http://flybase.org/reports/FBgn0264891 non_protein_coding_gene - - - CR44082 - CR44082 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020583 anon-59Cb anon-59Cb http://flybase.org/reports/FBgn0020583 - gene - - - anon-59Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083261 E(smoDN)830 Enhancer of smoDN 830 http://flybase.org/reports/FBgn0083261 gene - - - E(smoDN)830 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001562 l(1)19Fb lethal (1) 19Fb http://flybase.org/reports/FBgn0001562 - gene - - - "B-214, l(1)B-214, l(1)B214, B214, lB214-1, 11, 6, l(1)19Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage" "ovariole,germline clone,egg,dorsal appendage" FBgn0052517 CG32517 - http://flybase.org/reports/FBgn0052517 protein_coding_gene - - - CG32517 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019880 anon-69Ac anon-69Ac http://flybase.org/reports/FBgn0019880 - gene - - - anon-69Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - larval stage FBgn0031002 CG14196 - http://flybase.org/reports/FBgn0031002 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG14196 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG14196 11-Aug-17 DroID_v2017_08 "Drer\zgc:114041, Drer\slc16a8, Drer\si:ch211-234h8.7, Drer\slc16a6a, Drer\slc16a5b, Drer\slc16a7, Drer\slc16a13, Drer\slc16a12a, Drer\slc16a12b, Drer\slc16a6b" "Scer\ESBP6, Scer\MCH4, Scer\MCH5, Scer\MCH2, Scer\ATG22" "Cele\mct-2, Cele\slcf-1" Xtro\slc16a6 "Mmus\Slc16a6, Mmus\Slc16a11, Mmus\Slc16a12, Mmus\Slc16a4, Mmus\Slc16a7" "Hsap\SLC16A11, Hsap\SLC16A13, Hsap\SLC16A3, Hsap\SLC16A7, Hsap\SLC16A1, Hsap\SLC16A12, Hsap\SLC16A4, Hsap\SLC16A6" FBgn0002678 fs(2)abc female sterile abnormal chromatin http://flybase.org/reports/FBgn0002678 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "syn-PL63, abc, mat(2)synPL63, mat(2)syn-F, fs(2)abc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female semi-sterile,recessive,female sterile,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,maternal effect,partially lethal - majority die" "syncytial blastoderm embryo,yolk nucleus,spindle,centrosome,aster,endochorion,pole cell,maternal effect,nucleus | embryonic stage 4" FBgn0259976 pag parva germina http://flybase.org/reports/FBgn0259976 gene - oogenesis ; GO:0048477 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype - pag - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile,recessive,male sterile" "female germline cell,ovariole,ovary,testis,male germline cell,female fusome,spectrosomevin7)" FBgn0263628 CR43637 - http://flybase.org/reports/FBgn0263628 non_protein_coding_gene - - - CR43637 - CR43637 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010816 l(3)03773 lethal (3) 03773 http://flybase.org/reports/FBgn0010816 - gene - - - l(3)03773 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028367 l(1)10Al lethal (1) 10Al http://flybase.org/reports/FBgn0028367 gene - - - l(1)10Al - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024758 EC76 EC76 http://flybase.org/reports/FBgn0024758 - gene - - - EC76 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,non-enhancer of variegation" FBgn0051278 CG31278 - http://flybase.org/reports/FBgn0051278 protein_coding_gene peptide deformylase activity ; GO:0042586 | inferred from biological aspect of ancestor with PANTHER:PTN000048655 co-translational protein modification ; GO:0043686 | inferred from biological aspect of ancestor with PANTHER:PTN000048655 N-terminal protein amino acid modification ; GO:0031365 | inferred from biological aspect of ancestor with PANTHER:PTN000048655 - "PDF, CG6482, CG31278" IPR023635:Peptide deformylase CG31278 11-Aug-17 DroID_v2017_08 Drer\pdf - - Xtro\pdf Mmus\Pdf Hsap\PDF "viable,fertile" FBgn0063412 l(3)3450-K lethal (3) 3450-K http://flybase.org/reports/FBgn0063412 gene - - - l(3)3450-K - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0264508 CR43907 - http://flybase.org/reports/FBgn0264508 non_protein_coding_gene - - - CR43907 - CR43907 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003364 sesG stress-sensitive G http://flybase.org/reports/FBgn0003364 - gene - - - sesG - - 11-Aug-17 DroID_v2017_08 - - - - - - "hyperactive,bang sensitive" FBgn0039476 CG6271 - http://flybase.org/reports/FBgn0039476 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG6271, DmelL1" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6271 11-Aug-17 DroID_v2017_08 "Drer\LOC100331214, Drer\lpl, Drer\pla1a, Drer\lipia, Drer\lipib, Drer\lipg, Drer\lipca, Drer\LOC101884800" - - "Xtro\lpl, Xtro\lipg" "Mmus\Pnliprp1, Mmus\Pla1a, Mmus\Lipi, Mmus\Lpl, Mmus\Liph, Mmus\Lipc, Mmus\Pnliprp2, Mmus\Lipg, Mmus\Pnlip" "Hsap\PNLIPRP2, Hsap\LIPG, Hsap\LIPC, Hsap\LIPI, Hsap\PNLIPRP1, Hsap\PLA1A, Hsap\LIPH, Hsap\PNLIP, Hsap\PNLIPRP3, Hsap\LPL" FBgn0033785 Sans Scaffold protein containing ankyrin repeats and SAM domain http://flybase.org/reports/FBgn0033785 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available early endosome ; GO:0005769 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:2450757 "CG13320, DSANS, Sans" "IPR001660:Sterile alpha motif domain, IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR013761:Sterile alpha motif/pointed domain" CG13320 11-Aug-17 DroID_v2017_08 "Drer\anks4b, Drer\ush1ga, Drer\ush1gb" "Scer\AKR1, Scer\AKR2" Cele\mlt-3 Xtro\ush1g "Mmus\Anks4b, Mmus\Ush1g" "Hsap\ANKS4B, Hsap\USH1G" "viable,male fertile,female fertile,fertile,partially lethal - majority die,some die during pupal stage" DRSC06357 I 1.910247429 -0.186742376 0.435831611 0.454477484 -0.12212103 -0.361330162 FBgn0084825 C42 C42 http://flybase.org/reports/FBgn0084825 gene - - - C42 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0067878 Mod(Prat:bw)2-5 Mod(Prat:bw)2-5 http://flybase.org/reports/FBgn0067878 gene - - - "Mod-2-5, Mod(Prat:bw)2-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,recessive,suppressor of variegation" wing FBgn0014112 anon-84Ba anon-84Ba http://flybase.org/reports/FBgn0014112 - gene - - - "Z, anon-84Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage && larval stage FBgn0265399 EP2081 - http://flybase.org/reports/FBgn0265399 gene - - - EP2081 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082979 snoRNA:Psi28S-3091a snoRNA:Psi28S-3091a http://flybase.org/reports/FBgn0082979 snoRNA_gene - - - "snoRNA:Psi28S-3091a, psi28s-3091a, Psi 28S-3091a, CR34610, chr3R:1422405..1422506" - CR34610 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014849 Eig71Ei Eig71Ei http://flybase.org/reports/FBgn0014849 - protein_coding_gene - defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 metamorphosis ; GO:0007552 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model "L71, CG7327, L71-9, Eig71Ei, EIG71-EI" IPR003475:Insect protein of unknown function CG7327 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0063921 M(UAS-dsh)8-3 M(UAS-dsh)8-3 http://flybase.org/reports/FBgn0063921 gene molecular_function ; GO:0003674 | no biological data available Wnt signaling pathway ; GO:0016055 | inferred from genetic interaction with dsh cellular_component ; GO:0005575 | no biological data available "UAS-dsh M[8-3], M(UAS-dsh)8-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262108 CR42861 - http://flybase.org/reports/FBgn0262108 non_protein_coding_gene - - - CR42861 - CR42861 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085611 CG41318 - http://flybase.org/reports/FBgn0085611 protein_coding_gene - - - CG41318 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083309 E(smoDN)1422 Enhancer of smoDN 1422 http://flybase.org/reports/FBgn0083309 gene - - - E(smoDN)1422 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038139 PK2-R2 Pyrokinin 2 receptor 2 http://flybase.org/reports/FBgn0038139 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity inferred from direct assay pyrokinin receptor activity ; GO:0036401 | inferred from physical interaction with Hug peptide receptor activity ; GO:0001653 | inferred from direct assay neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay "anon-WO0170980.194, anon-WO0170980.193, Dm CG8795, CG8795, PK2-R2" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG8795 11-Aug-17 DroID_v2017_08 "Drer\mlnr, Drer\gpr39, Drer\nmur1b, Drer\ntsr1, Drer\LOC103910036, Drer\LOC101885431, Drer\ghsra, Drer\nmur3, Drer\LOC101885494, Drer\LOC101885849, Drer\ghsrb, Drer\nmur1a" - "Cele\npr-32, Cele\nmur-4, Cele\nmur-2, Cele\nmur-1, Cele\nmur-3" Xtro\nmur2 "Mmus\Nmur2, Mmus\Olfr979, Mmus\Gpr39, Mmus\Ntsr1, Mmus\Ghsr, Mmus\Nmur1, Mmus\Ntsr2" "Hsap\NMUR2, Hsap\NMUR1, Hsap\NTSR1, Hsap\NTSR2, Hsap\GPR39, Hsap\GHSR, Hsap\OR10G7, Hsap\MLNR, Hsap\GPR148" "viable,fertile,partially lethal - majority die,some die during pupal stage,lethal" DRSC16448 K 0.682739662 -1.029197156 -0.213406505 0.078407615 0.262222898 1.746703115 FBgn0010498 l(2)01848 lethal (2) 01848 http://flybase.org/reports/FBgn0010498 - gene - - - l(2)01848 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0015977 l(2)PC4-C lethal (2) PC4-C http://flybase.org/reports/FBgn0015977 - gene - - - l(2)PC4-C - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038424 CG17565 - http://flybase.org/reports/FBgn0038424 protein_coding_gene protein farnesyltransferase activity ; GO:0004660 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000206624 regulation of cell proliferation ; GO:0042127 | inferred from electronic annotation with InterPro:IPR026872 protein farnesylation ; GO:0018343 | inferred from biological aspect of ancestor with PANTHER:PTN000206624 protein farnesyltransferase complex ; GO:0005965 | inferred from biological aspect of ancestor with PANTHER:PTN000206624 "CG17565, FNTB" "IPR001330:PFTB repeat, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR026872:Protein farnesyltransferase subunit beta" CG17565 11-Aug-17 DroID_v2017_08 Drer\fntb Scer\RAM1 Cele\fntb-1 Xtro\fntb "Mmus\Churc1, Mmus\Fntb" "Hsap\FNTB, Hsap\CHURC1-FNTB, Hsap\CHURC1" "viable,visible,planar polarity defective" "mesothoracic tergum,wing | pupal stage,wing hair | pupal stage" FBgn0023046 l(1)3Aq lethal (1) 3Aq http://flybase.org/reports/FBgn0023046 - gene - - - "1200D14, l(1)3Aq" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034699 CG13504 - http://flybase.org/reports/FBgn0034699 protein_coding_gene - - - CG13504 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22823 IE -1.9321045 0.483726101 -0.499286229 -1.838104186 -0.590274832 -0.610598497 FBgn0263633 mir-3644 mir-3644 stem loop http://flybase.org/reports/FBgn0263633 miRNA_gene - - - "mir-3644, CR43559" - CR43559 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013397 anon-96Fb anon-96Fb http://flybase.org/reports/FBgn0013397 - gene - - - anon-96Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , larval stage " " adult head

, eye-antennal disc

" FBgn0010325 K27 K27 http://flybase.org/reports/FBgn0010325 - gene - - - K27 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031008 CG8010 - http://flybase.org/reports/FBgn0031008 protein_coding_gene - - - CG8010 IPR032056:Protein of unknown function DUF4798 CG8010 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC20072 K -0.329002261 0.762185957 -0.01478485 -0.100817361 1.501205961 0.34340924 FBgn0260874 Ir76a Ionotropic receptor 76a http://flybase.org/reports/FBgn0260874 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model olfactory receptor activity ; GO:0004984 | contributes_to inferred from direct assay transmission of nerve impulse ; GO:0019226 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay sensory dendrite ; GO:0071683 | inferred from direct assay receptor complex ; GO:0043235 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG42584, CG8533, IR76a, Ir76a, CT24909, CG34257, DmelIR76a, ir76a" - CG42584 11-Aug-17 DroID_v2017_08 "Drer\grik2, Drer\grid2, Drer\grid1b, Drer\LOC100537813, Drer\LOC100334689, Drer\grik5, Drer\grid1a" - "Cele\glr-6, Cele\glr-3, Cele\F59E12.8" - "Mmus\Grik3, Mmus\Grik2, Mmus\Grik5, Mmus\Grid1, Mmus\Grid2" "Hsap\GRID2, Hsap\GRIK3, Hsap\GRID1, Hsap\GRIK2, Hsap\GRIK5" FBgn0039951 CG12579 - http://flybase.org/reports/FBgn0039951 protein_coding_gene - - - CG12579 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027966 l(3)S144912 lethal (3) S144912 http://flybase.org/reports/FBgn0027966 gene - - - "1449/12, l(3)S144912" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003534 sto stocky http://flybase.org/reports/FBgn0003534 - gene - - - "tpw, sto" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,female sterile,partially,body color defective,male sterile,male,reduced" "wing,eye,adult abdomen,macrochaeta" FBgn0031918 CG6055 - http://flybase.org/reports/FBgn0031918 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - CG6055 "IPR001304:C-type lectin-like, IPR018378:C-type lectin, conserved site, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG6055 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-28d5.15, Drer\si:dkey-28d5.4, Drer\si:dkey-83f18.7, Drer\si:dkey-83f18.10, Drer\si:ch211-282j17.11, Drer\si:dkey-28d5.8, Drer\si:dkey-28d5.12, Drer\si:ch211-282j17.8, Drer\si:dkey-88n24.10, Drer\si:ch211-225k7.2, Drer\si:dkey-28d5.14, Drer\si:ch211-63p21.4, Drer\si:ch211-282j17.7, Drer\si:dkey-28d5.10, Drer\si:ch211-225k7.3" - - - Mmus\Sell "Hsap\CLEC3B, Hsap\SELL" viable FBgn0015473 l(2)45Aa lethal (2) 45Aa http://flybase.org/reports/FBgn0015473 - gene - - - l(2)45Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0032774 CG17549 - http://flybase.org/reports/FBgn0032774 protein_coding_gene - - - CG17549 - CG17549 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0267506 pre-rRNA:CR45846 ribosomal RNA primary transcript:CR45846 http://flybase.org/reports/FBgn0267506 rRNA_gene - - - "pre-rRNA:CR45846, CR45846" - CR45846 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033656 S2P site-2 protease http://flybase.org/reports/FBgn0033656 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001193, InterPro:IPR008915" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001193, InterPro:IPR008915 ATF6-mediated unfolded protein response ; GO:0036500 | inferred from biological aspect of ancestor with PANTHER:PTN000330398 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress ; GO:1990440 | inferred from biological aspect of ancestor with PANTHER:PTN000330398 positive regulation of sequence-specific DNA binding transcription factor activity ; GO:0051091 | inferred from biological aspect of ancestor with PANTHER:PTN000330398 sterol regulatory element binding protein cleavage ; GO:0035103 | non-traceable author statement" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001193 "dS2P, CG8988, anon-WO0118547.346, S2P, ds2p" "IPR001193:Membrane-bound transcription factor site-2 protease, IPR008915:Peptidase M50, IPR001478:PDZ domain" CG8988 11-Aug-17 DroID_v2017_08 Drer\mbtps2 - Cele\Y56A3A.2 Xtro\mbtps2 Mmus\Mbtps2 Hsap\MBTPS2 "viable,fertile,conditional,small body,lethal - all die before end of larval stage,some die during larval stage" FBgn0032474 DnaJ-H DnaJ homolog http://flybase.org/reports/FBgn0032474 protein_coding_gene "unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001305, InterPro:IPR008971 heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001305" protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971 - "dDnaJ-H, CG9828, NEST:bs08d07, DnaJ-H, dHdj2, dnaJ-H, DNA J-H, DNAJ-H" "IPR001305:Heat shock protein DnaJ, cysteine-rich domain, IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site" CG9828 11-Aug-17 DroID_v2017_08 "Drer\dnajb4, Drer\dnajb1a, Drer\dnaja1, Drer\dnaja2l, Drer\dnajb5, Drer\dnajc22, Drer\dnaja2, Drer\dnajb11, Drer\dnajb2" "Scer\ERJ5, Scer\APJ1, Scer\SCJ1, Scer\XDJ1, Scer\YDJ1, Scer\JJJ1" "Cele\dnj-22, Cele\dnj-13, Cele\dnj-12, Cele\dnj-19, Cele\dnj-1, Cele\F54F2.9, Cele\dnj-20" "Xtro\dnaja2, Xtro\dnaja1, Xtro\dnaja4.1, Xtro\dnaja4.2, Xtro\dnajb11" "Mmus\Dnajb11, Mmus\Dnajb1, Mmus\Dnajb4, Mmus\Dnajb5, Mmus\Dnaja2, Mmus\Dnaja1, Mmus\Dnajc22, Mmus\Dnaja4" "Hsap\DNAJB4, Hsap\DNAJA1, Hsap\DNAJB5, Hsap\DNAJA2, Hsap\DNAJB11, Hsap\DNAJB1, Hsap\DNAJA4, Hsap\DNAJC22" viable FBgn0053474 CG33474 - http://flybase.org/reports/FBgn0053474 protein_coding_gene - peroxisome fission ; GO:0016559 | inferred from electronic annotation with InterPro:IPR008733 integral component of peroxisomal membrane ; GO:0005779 | inferred from electronic annotation with InterPro:IPR008733 CG33474 "IPR008733:Peroxisomal biogenesis factor 11, IPR026510:Peroxisomal membrane protein 11C, metazoa" CG33474 11-Aug-17 DroID_v2017_08 "Drer\pex11g, Drer\pex11a, Drer\pex11b" Scer\PEX11 Cele\prx-11 "Xtro\pex11b, Xtro\pex11a, Xtro\pex11g" "Mmus\Pex11b, Mmus\Pex11a, Mmus\Pex11g" "Hsap\PEX11A, Hsap\PEX11B, Hsap\PEX11G" FBgn0041734 mali mali http://flybase.org/reports/FBgn0041734 gene - - - mali - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,chemical resistant,dominant,lethal,recessive,hyperplasia" "salivary gland,melanotic mass,polytene chromosome,embryonic/larval brain" FBgn0036066 CG14160 - http://flybase.org/reports/FBgn0036066 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 CG14160 "IPR020846:Major facilitator superfamily domain, IPR005828:Major facilitator, sugar transporter-like" CG14160 11-Aug-17 DroID_v2017_08 "Drer\slc2a10, Drer\LOC101882338, Drer\slc2a8, Drer\slc2a12, Drer\slc2a6, Drer\slc2a13b" "Scer\HXT3, Scer\RGT2, Scer\MAL11, Scer\YDL199C, Scer\VBA2, Scer\YDR387C, Scer\HXT11, Scer\YFL040W, Scer\HXT8, Scer\HXT10, Scer\GEX2, Scer\STL1, Scer\HXT15, Scer\MPH2, Scer\MPH3, Scer\AZR1, Scer\HXT13, Scer\SNF3, Scer\VBA4, Scer\HXT2, Scer\HXT6, Scer\HXT5, Scer\HXT14, Scer\ITR2, Scer\ITR1, Scer\GEX1, Scer\HXT4, Scer\HXT7, Scer\MAL31, Scer\HXT17, Scer\YMR279C, Scer\VBA3, Scer\HXT9, Scer\VBA5, Scer\VBA1, Scer\SGE1, Scer\HXT16, Scer\GAL2, Scer\HXT1, Scer\ATR1, Scer\ENB1" "Cele\fgt-1, Cele\hmit-1.2" "Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a12" "Mmus\Slc2a10, Mmus\Slc2a8, Mmus\Slc2a13, Mmus\Slc2a2, Mmus\Slc2a6, Mmus\Slc2a12" "Hsap\SLC2A6, Hsap\SLC2A2, Hsap\SLC2A8, Hsap\SLC2A13, Hsap\SLC2A12, Hsap\SLC2A10" viable FBgn0004126 hum humilis http://flybase.org/reports/FBgn0004126 - gene - - - hum - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,viable" FBgn0000059 ag agametic http://flybase.org/reports/FBgn0000059 - gene - gonad development ; GO:0008406 | inferred from mutant phenotype - ag - - 11-Aug-17 DroID_v2017_08 - - - - - - "grandchildless,semidominant" "pole cell,gonad" FBgn0014234 l(2)31Eq lethal (2) 31Eq http://flybase.org/reports/FBgn0014234 - gene - - - l(2)31Eq - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037897 CG5270 - http://flybase.org/reports/FBgn0037897 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 - - CG5270 "IPR000306:FYVE zinc finger, IPR011011:Zinc finger, FYVE/PHD-type, IPR017455:Zinc finger, FYVE-related, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5270 11-Aug-17 DroID_v2017_08 "Drer\zfyve26, Drer\plekhf2, Drer\plekhm2, Drer\snx29, Drer\plekhf1" - "Cele\ZK632.12, Cele\aka-1" Xtro\zfyve26 "Mmus\Snx29, Mmus\Plekhf1, Mmus\Plekhm2, Mmus\Plekhf2, Mmus\Zfyve26" "Hsap\PLEKHM2, Hsap\SNX29, Hsap\PLEKHF2, Hsap\PLEKHF1, Hsap\ZFYVE26" viable FBgn0058458 2SrRNA:CR40458 2SrRNA:CR40458 http://flybase.org/reports/FBgn0058458 rRNA_gene - - - "CR40458, 2SrRNA:CR40458" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040565 CG7606 - http://flybase.org/reports/FBgn0040565 protein_coding_gene - - - CG7606 - CG7606 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041147 ida imaginal discs arrested http://flybase.org/reports/FBgn0041147 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | traceable author statement regulation of proteolysis ; GO:0030162 | traceable author statement anaphase-promoting complex ; GO:0005680 | inferred from sequence or structural similarity with HGNC:15713 anaphase-promoting complex ; GO:0005680 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "CG10850, APC5, l(3)63Fb, l(3)SH7, ida, IDA, Apc5, Ida" "IPR011990:Tetratricopeptide-like helical domain, IPR026000:Anaphase-promoting complex subunit 5" CG10850 11-Aug-17 DroID_v2017_08 Drer\anapc5 Scer\APC5 "Cele\gfi-3, Cele\such-1" Xtro\anapc5 Mmus\Anapc5 Hsap\ANAPC5 "neuroanatomy defective,mitotic cell cycle defective,lethal - all die before end of P-stage,recessive,some die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal,lethal - all die before end of prepupal stage,some die during prepupal stage,female sterile,germline clone,viable,visible" "embryonic/larval brain,embryonic/larval optic lobe,testis,imaginal disc,air bubble,foregut imaginal ring,hindgut imaginal ring,salivary gland imaginal ring,midgut imaginal island,mitotic cell cycle,mitotic prometaphase,mitotic anaphase,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC08163 IE 2.227430572 0.534534691 2.062243328 -0.18819315 -0.692688187 -0.47589496 FBgn0051796 CG31796 - http://flybase.org/reports/FBgn0051796 protein_coding_gene - - - CG31796 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037459 CG15184 - http://flybase.org/reports/FBgn0037459 protein_coding_gene - - - CG15184 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC12564 EK 0.679753286 1.268542767 0.262387438 2.001158041 0.309910891 1.831993351 FBgn0000985 fs(2)K female sterile (2) K http://flybase.org/reports/FBgn0000985 - gene - - - "fes(2)k, fes(2)K, fs(2)K" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,male fertile" FBgn0001735 l(1)HM3 lethal (1) HM3 http://flybase.org/reports/FBgn0001735 - gene - - - l(1)HM3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female semi-sterile,heat sensitive" FBgn0016817 l(1)L2 lethal (1) L2 http://flybase.org/reports/FBgn0016817 - gene - - - "l(1)L2, L2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261673 nemy no extended memory http://flybase.org/reports/FBgn0261673 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of synaptic plasticity ; GO:0048167 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from mutant phenotype - "CytB561, CG8776, nemy, anon-WO0140519.146, CG13147, P153, Nemy" IPR006593:Cytochrome b561/ferric reductase transmembrane CG8776 11-Aug-17 DroID_v2017_08 "Drer\cybrd1, Drer\dcaf17, Drer\cyb561, Drer\cyb561a3a, Drer\cyb561a3b" Scer\HOS4 "Cele\F39G3.4, Cele\glna-2, Cele\gls-1, Cele\F39G3.5, Cele\F55H2.5, Cele\glna-1" "Xtro\cybrd1, Xtro\cyb561" "Mmus\Cyb561, Mmus\Cybrd1, Mmus\Gls2, Mmus\Cyb561a3" "Hsap\CYB561, Hsap\CYBRD1, Hsap\GLS2, Hsap\CYB561A3" DRSC05357 K -0.149878689 -0.262002555 0.239305641 0.006167622 1.166674553 3.084038938 FBgn0031395 CG10874 - http://flybase.org/reports/FBgn0031395 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:28163 centrosome ; GO:0005813 | inferred from sequence or structural similarity with HGNC:28163 "CG10874, FBgn 31395" IPR025271:Domain of unknown function DUF4061 CG10874 11-Aug-17 DroID_v2017_08 "Drer\ccdc28a, Drer\ccdc28b" - - Xtro\ccdc28b "Mmus\Ccdc28b, Mmus\Ccdc28a" "Hsap\CCDC28A, Hsap\CCDC28B" FBgn0001144 gs(1)N41 grandchildless N41 http://flybase.org/reports/FBgn0001144 - gene molecular_function ; GO:0003674 | no biological data available nuclear migration ; GO:0007097 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "gs(1)N441, gs(1)441, gs(1)N41" - - 11-Aug-17 DroID_v2017_08 - - - - - - grandchildless cleavage nucleus FBgn0052166 CG32166 - http://flybase.org/reports/FBgn0052166 protein_coding_gene - - - CG32166 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083277 E(smoDN)2546 Enhancer of smoDN 2546 http://flybase.org/reports/FBgn0083277 gene - - - E(smoDN)2546 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051921 CG31921 - http://flybase.org/reports/FBgn0051921 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs08h12, CG31921" - CG31921 11-Aug-17 DroID_v2017_08 - - - - - Hsap\VGF viable FBgn0267101 CR45541 - http://flybase.org/reports/FBgn0267101 non_protein_coding_gene - - - CR45541 - CR45541 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033957 CG12865 - http://flybase.org/reports/FBgn0033957 protein_coding_gene - - - CG12865 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0027515 CG7115 - http://flybase.org/reports/FBgn0027515 - protein_coding_gene cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR000222 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000002164 protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002164 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002164 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002164 "PP2C, BcDNA:LD21794, CG7115, dPPM1L" "IPR000222:PPM-type phosphatase, divalent cation binding, IPR001932:PPM-type phosphatase domain, IPR015655:Protein phosphatase 2C family" CG7115 11-Aug-17 DroID_v2017_08 "Drer\ppm1k, Drer\ppm1da, Drer\si:ch211-149b19.3, Drer\ppm1f, Drer\ppm1lb, Drer\tab1, Drer\ilkap, Drer\ppm1e, Drer\ppm1la" "Scer\PTC6, Scer\PTC1, Scer\PTC4" Cele\ppm-2 "Xtro\ppm1d, Xtro\ppm1l, Xtro\tab1, Xtro\ppm1f, Xtro\ppm1k, Xtro\ppm1e, Xtro\ilkap" "Mmus\Ppm1f, Mmus\Tab1, Mmus\Ppm1d, Mmus\Pp2d1, Mmus\Ppm1l, Mmus\Ilkap, Mmus\Ppm1k, Mmus\Ppm1e" "Hsap\ILKAP, Hsap\PPM1L, Hsap\PPM1K, Hsap\PPM1E, Hsap\PP2D1, Hsap\TAB1, Hsap\PPM1F, Hsap\PPM1D" viable DRSC02000 E 0.3476742 0.258115545 -0.323878302 -1.818197598 0.636824272 -0.063677313 FBgn0031546 CG8851 - http://flybase.org/reports/FBgn0031546 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG8851 - CG8851 11-Aug-17 DroID_v2017_08 - Scer\SMC4 - - "Mmus\Ccdc171, Mmus\Ckap4" "Hsap\CKAP4, Hsap\CEP128" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0023149 Su(mg)3-3 Suppressor of modifier of gypsy 3-3 http://flybase.org/reports/FBgn0023149 - gene - - - Su(mg)3-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037418 Osi11 Osiris 11 http://flybase.org/reports/FBgn0037418 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi11, CG15596, osi11" IPR012464:Protein of unknown function DUF1676 CG15596 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033232 CG12159 - http://flybase.org/reports/FBgn0033232 protein_coding_gene - - - CG12159 IPR009565:Protein of unknown function DUF1180 CG12159 11-Aug-17 DroID_v2017_08 Drer\fam174b - - Xtro\fam174a "Mmus\1600002K03Rik, Mmus\Fam174a, Mmus\Fam174b" "Hsap\FAM174A, Hsap\C19orf24, Hsap\FAM174B" viable FBgn0065310 l(2)SH1954 lethal (2) SH1954 http://flybase.org/reports/FBgn0065310 gene - - - "l(2)SH1954, l(2)SH2 1954" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086546 MRE14 mRNA-like ncRNA in embryogenesis 14 http://flybase.org/reports/FBgn0086546 non_protein_coding_gene - - - "MRE14, GM10545" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034290 CG5773 - http://flybase.org/reports/FBgn0034290 protein_coding_gene - - - "CG5773, BcDNA:RH46075" - CG5773 11-Aug-17 DroID_v2017_08 - - - - - - DRSC06955 I -0.921156885 -3.165904852 -0.461414193 -1.41936047 -0.146770431 -0.594805759 FBgn0013277 Hsp70Ba Heat-shock-protein-70Ba http://flybase.org/reports/FBgn0013277 "FBgn0001232, FBgn0051449" protein_coding_gene - response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from mutant phenotype response to heat ; GO:0009408 | non-traceable author statement response to unfolded protein ; GO:0006986 | non-traceable author statement response to heat ; GO:0009408 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "Hsp70, hsp70, HSP70, hsp70B, hsp70Ba, Hsp70B, Hsp 70, dhsp70, Hsp70(87C), hsp-70, hsp70 87C, CG31449, Hsp70Ba, Hsp-70, dHsp70, hsp70 Ba, Dm-hsp70, hsp70b, hsp70ba" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG31449 11-Aug-17 DroID_v2017_08 "Drer\hsp70.1, Drer\hspa8, Drer\hspa5, Drer\hsp70.2, Drer\si:dkey-4p15.3, Drer\si:ch211-199o1.2, Drer\hspa14, Drer\hspa12a, Drer\hsp70l, Drer\hsc70, Drer\hspa13, Drer\nckap1, Drer\hspa12b" "Scer\SSA3, Scer\KAR2, Scer\SSA4, Scer\SSB1, Scer\SSQ1, Scer\SSA2, Scer\SSA1, Scer\SSB2, Scer\SSZ1" "Cele\hsp-4, Cele\F44E5.5, Cele\gex-3, Cele\hsp-70, Cele\hsp-3, Cele\hsp-1, Cele\F44E5.4, Cele\F11F1.1" "Xtro\hsp70, Xtro\hspa1a, Xtro\hspa14, Xtro\hspa13, Xtro\hspa12b, Xtro\nckap1l, Xtro\hspa1b, Xtro\hspa5, Xtro\hspa2, Xtro\hspa8, Xtro\hspa1l, Xtro\nckap1" "Mmus\Hspa1a, Mmus\Hspa1l, Mmus\Hspa2, Mmus\Hspa5, Mmus\Hspa13, Mmus\Nckap1, Mmus\Hspa14, Mmus\Hspa12b, Mmus\Hspa8, Mmus\Hspa1b, Mmus\Hspa12a, Mmus\Nckap1l" "Hsap\NCKAP1, Hsap\HSPA6, Hsap\HSPA1B, Hsap\HSPA5, Hsap\NCKAP1L, Hsap\HSPA13, Hsap\HSPA14, Hsap\HSPA2, Hsap\HSPA12A, Hsap\HSPA1A, Hsap\HSPA1L, Hsap\HSPA8, Hsap\HSPA12B" "heat stress response defective,viable" DRSC21247 IEK -0.467713773 -2.303890615 -1.000773181 -2.105013559 1.780812858 1.367888199 FBgn0015621 Clp Clipper http://flybase.org/reports/FBgn0015621 FBgn0014034 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000559726 endoribonuclease activity ; GO:0004521 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000559726 mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with protein_id:AAD00321 mRNA polyadenylation ; GO:0006378 | inferred from sequence or structural similarity with protein_id:AAD00321 pre-mRNA cleavage required for polyadenylation ; GO:0098789 | inferred from biological aspect of ancestor with PANTHER:PTN000559780 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000559726 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from sequence or structural similarity with protein_id:AAD00321 "CG3642, c6a, clp, CLP, Ssb-c6a, Clp, CPSF30, Cpsf30" "IPR000571:Zinc finger, CCCH-type, IPR001878:Zinc finger, CCHC-type" CG3642 11-Aug-17 DroID_v2017_08 "Drer\cpsf4, Drer\zc3h4" Scer\YTH1 Cele\cpsf-4 "Xtro\zc3h6, Xtro\cpsf4, Xtro\cpsf4l" "Mmus\Zc3h6, Mmus\Zc3h8, Mmus\Cpsf4, Mmus\Cpsf4l, Mmus\Zc3h4" "Hsap\ZC3H6, Hsap\CPSF4L, Hsap\ZC3H8, Hsap\CPSF4, Hsap\ZC3H4" " embryonic stage | early , oogenesis stage && adult stage | female , embryonic stage -- adult stage , embryonic stage | stage <5 , adult stage && oogenesis stage | stage S3-8 " " ovary

, organism

, oocyte | posterior

" " larval stage , oogenesis stage , adult stage && oogenesis stage " " oocyte

, follicle cell

" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell" DRSC00746 I 1.518303126 2.724712601 0.158953175 -0.758051477 0.078246147 0.275961644 FBgn0025151 ms(2)A5 ms(2)A5 http://flybase.org/reports/FBgn0025151 - gene - - - ms(2)A5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0024256 acd(2)5N30 auditory courtship defective 5N30 http://flybase.org/reports/FBgn0024256 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5N30 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective,courtship behavior defective,male sterile" testis FBgn0004105 flrd393 flight reduced 393 http://flybase.org/reports/FBgn0004105 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "flrd-393, flrd393" - - 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,male,flight defective" FBgn0037487 thw thawb http://flybase.org/reports/FBgn0037487 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG14608, thw" IPR002557:Chitin binding domain CG14608 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - viable FBgn0263453 CR43476 - http://flybase.org/reports/FBgn0263453 non_protein_coding_gene - - - CR43476 - CR43476 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017486 Su(crc)2 Suppressor of cryptocephal 2 http://flybase.org/reports/FBgn0017486 - gene - - - "Su2, Su(crc)2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000608 e(w[e]) enhancer of white-eosin http://flybase.org/reports/FBgn0000608 - gene - - - "en-w[e], e(w[e])" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,visible" "wing vein,wing" FBgn0259353 EP-687 - http://flybase.org/reports/FBgn0259353 gene - - - EP-687 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing margin,chaeta" FBgn0260750 Mulk Multi-substrate lipid kinase http://flybase.org/reports/FBgn0260750 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 ceramide kinase activity ; GO:0001729 | inferred from direct assay ceramide metabolic process ; GO:0006672 | inferred from mutant phenotype pole cell migration ; GO:0007280 | inferred from genetic interaction with Cerk lipid phosphorylation ; GO:0046834 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "CG18162, anon-31BCb, CG31873, Mulk, Dmulk" "IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR001206:Diacylglycerol kinase, catalytic domain, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG31873 11-Aug-17 DroID_v2017_08 "Drer\agk, Drer\cerk" "Scer\LCB4, Scer\LCB5" Cele\F52C9.3 Xtro\agk Mmus\Agk Hsap\AGK DRSC02658 E 0.91469936 -0.864726558 -4.092363166 0.862479657 -0.264882746 0.524823966 FBgn0263197 Patronin Patronin http://flybase.org/reports/FBgn0263197 protein_coding_gene calmodulin binding ; GO:0005516 | inferred from electronic annotation with InterPro:IPR031372 spectrin binding ; GO:0030507 | inferred from electronic annotation with InterPro:IPR031372 microtubule minus-end binding ; GO:0051011 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with HGNC:19946 neuron projection development ; GO:0031175 | inferred from electronic annotation with InterPro:IPR031372 microtubule severing ; GO:0051013 | inferred from mutant phenotype negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay spindle ; GO:0005819 | colocalizes_with inferred from direct assay midbody ; GO:0030496 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay "Patronin, CG33130, ssp4, CG18462, CG18460, CG18459, CG30102, CG6516, BcDNA:LD17191, Ssp4, l(2)k07433" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001715:Calponin homology domain, IPR011033:PRC-barrel-like, IPR014797:CKK domain, IPR022613:Calmodulin-regulated spectrin-associated protein, CH domain, IPR031372:CAMSAP, spectrin and Ca2+/calmodulin-binding region, IPR032940:Calmodulin-regulated spectrin-associated protein" CG33130 11-Aug-17 DroID_v2017_08 "Drer\camsap2a, Drer\camsap2b, Drer\camsap1a, Drer\camsap3, Drer\camsap1b" - Cele\ptrn-1 "Xtro\camsap2, Xtro\camsap1, Xtro\camsap3" "Mmus\Camsap2, Mmus\Camsap3, Mmus\Camsap1" "Hsap\CAMSAP3, Hsap\CAMSAP2, Hsap\CAMSAP1" FBgn0005462 l(1)ts19 lethal (1) ts19 http://flybase.org/reports/FBgn0005462 - gene - - - l(1)ts19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0005588 anon-alaE anon-alaE http://flybase.org/reports/FBgn0005588 - repeat_region - - - "ALA-E6, ala-E, ala-B, anon-alaE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037307 Tim17a2 Tim17a2 http://flybase.org/reports/FBgn0037307 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:Q99595 protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000050380 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q99595 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q99595 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 "CG14666, BcDNA:RH03914, Tim17a2" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG14666 11-Aug-17 DroID_v2017_08 "Drer\timm17b, Drer\timm17a" Scer\TIM17 "Cele\D2096.1, Cele\E04A4.5" Xtro\timm17a "Mmus\Timm17a, Mmus\Timm17b" "Hsap\TIMM17A, Hsap\TIMM17B" "viable,visible" trichogen cell FBgn0267323 CR45759 - http://flybase.org/reports/FBgn0267323 non_protein_coding_gene - - - "CR45759, lincRNA.458" - CR45759 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259203 CG42307 - http://flybase.org/reports/FBgn0259203 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42307 - CG42307 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042101 CG18744 - http://flybase.org/reports/FBgn0042101 protein_coding_gene - - - CG18744 "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG18744 11-Aug-17 DroID_v2017_08 "Drer\arrdc2, Drer\arrdc1a, Drer\zgc:110353, Drer\txnipa, Drer\arrdc3b, Drer\arrdc3a, Drer\zgc:110626, Drer\arrdc1b, Drer\LOC799768, Drer\si:ch211-130m23.2, Drer\txnipb" "Scer\ROD1, Scer\ECM21, Scer\LDB19, Scer\ROG3, Scer\ART5, Scer\ALY1, Scer\RIM8, Scer\CSR2, Scer\ALY2" "Cele\arrd-19, Cele\arrd-27, Cele\arrd-24, Cele\arrd-14, Cele\arrd-25, Cele\arrd-9, Cele\arrd-13, Cele\arrd-5, Cele\rnh-1.2, Cele\arrd-2, Cele\arrd-4, Cele\arrd-16, Cele\arrd-18, Cele\arrd-15, Cele\arrd-3, Cele\arrd-23, Cele\arrd-22, Cele\arrd-8, Cele\arrd-12, Cele\arrd-1, Cele\arrd-6, Cele\arrd-11, Cele\arrd-7" "Xtro\arrdc2, Xtro\txnip, Xtro\arrdc3, Xtro\arrdc4" "Mmus\Arrdc3, Mmus\Arrdc4, Mmus\Arrdc5, Mmus\Arrdc2, Mmus\Txnip, Mmus\Arrdc1" "Hsap\TXNIP, Hsap\ARRDC3, Hsap\ARRDC4, Hsap\ARRDC5, Hsap\ARRDC1, Hsap\ARRDC2" viable FBgn0033136 Tsp42Eo Tetraspanin 42Eo http://flybase.org/reports/FBgn0033136 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model "CG12838, Dm.Tsp42Eo, BcDNA:RH51444, Tsp42Eo" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12838 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000000545, Drer\tspan3b, Drer\prph2a, Drer\cd63, Drer\rom1a, Drer\rom1b, Drer\prph2b, Drer\prph2l, Drer\tspan36, Drer\tspan3a" - "Cele\tsp-21, Cele\tsp-18, Cele\tsp-5, Cele\tsp-7" - "Mmus\Tspan3, Mmus\Prph2, Mmus\Cd63" "Hsap\CD63, Hsap\PRPH2, Hsap\TSPAN15, Hsap\TSPAN3" viable FBgn0060906 l(3)S043418 lethal (3) S043418 http://flybase.org/reports/FBgn0060906 gene - - - "0434/18, l(3)S043418" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031657 CG3756 - http://flybase.org/reports/FBgn0031657 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR009025, InterPro:IPR011262 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000210383 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000210383" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR009025, InterPro:IPR011262, InterPro:IPR011263" DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN000210383 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000210383 microtubule associated complex ; GO:0005875 | inferred from direct assay CG3756 "IPR009025:DNA-directed RNA polymerase, RBP11-like dimerisation domain, IPR011262:DNA-directed RNA polymerase, insert domain, IPR011263:DNA-directed RNA polymerase, RpoA/D/Rpb3-type, IPR033901:DNA-directed RNA polymerases I and III subunit AC40" CG3756 11-Aug-17 DroID_v2017_08 Drer\polr1c Scer\RPC40 Cele\rpac-40 Xtro\polr1c Mmus\Polr1c Hsap\POLR1C viable FBgn0044402 Scim25 Sensitized chromosome inheritance modifier 25 http://flybase.org/reports/FBgn0044402 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype - Scim25 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "mitosis & nuclear chromosome,mitotic interphase,nuclear chromosome" FBgn0001052 Fs(3)Jut Female sterile (3) Jutas http://flybase.org/reports/FBgn0001052 - gene molecular_function ; GO:0003674 | no biological data available embryonic cleavage ; GO:0040016 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Jut, Fs(3)Jutas, Fs(3)Sz13, Fs(3)Jut" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cleavage stage embryo,maternal effect" FBgn0014306 l(3)neo53b lethal (3) neo53b http://flybase.org/reports/FBgn0014306 - gene - - - l(3)neo53b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043565 Su(hh)II Su(hh)II http://flybase.org/reports/FBgn0043565 gene - - - Su(hh)II - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011318 l(3)j1E7 lethal (3) j1E7 http://flybase.org/reports/FBgn0011318 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(3)j1E7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive,female sterile" "ovariole,germline clone,egg" FBgn0051383 tRNA:Leu-TAG-1-1 transfer RNA:Leucine-TAG 1-1 http://flybase.org/reports/FBgn0051383 tRNA_gene CUA codon-amino acid adaptor activity ; GO:0033419 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033419 cytosol ; GO:0005829 | inferred by curator from GO:0033419 "AE002708.trna33-LeuTAG, tRNA:L:TAG:AE002708-b, CR31383, chr3R.trna39-LeuTAG, tRNA-Leu-TAG-1-1, tRNA:Leu-TAG-1-1, tRNA:CR31383" - CR31383 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086234 whale whale http://flybase.org/reports/FBgn0086234 gene - - - whale - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031882 Rab30 Rab30 http://flybase.org/reports/FBgn0031882 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with BicD inferred from physical interaction with IKKε inferred from physical interaction with Sec5 protein binding ; GO:0005515 | inferred from physical interaction with BicD, GM130, Golgin245, GCC88, GCC185, cbs GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" "vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 germ-band shortening ; GO:0007390 | inferred from mutant phenotype" trans-Golgi network ; GO:0005802 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 synapse ; GO:0045202 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay endosome ; GO:0005768 | inferred from direct assay "AAF52477, DmRab30, CG9100, Rab30, rab30, Rab-30, Q9VM50" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9100 11-Aug-17 DroID_v2017_08 "Drer\rab30, Drer\rab43" "Scer\TEM1, Scer\YPT31, Scer\YPT32" Cele\rab-30 "Xtro\rab30, Xtro\rab19" "Mmus\Rab43, Mmus\Rab19, Mmus\Rab30" "Hsap\RAB43, Hsap\RAB30, Hsap\RAB19" "partially lethal - majority die,visible" "adult thorax,mesothoracic tergum,adult thoracic sensillum,scutellum,embryonic epidermis,dorsal,embryonic head" FBgn0265584 CR44411 - http://flybase.org/reports/FBgn0265584 non_protein_coding_gene - - - CR44411 - CR44411 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267682 CR46018 - http://flybase.org/reports/FBgn0267682 non_protein_coding_gene - - - CR46018 - CR46018 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052370 tRNA:Ala-AGC-2-1 transfer RNA:Alanine-AGC 2-1 http://flybase.org/reports/FBgn0052370 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "CR32370, AE002602.trna11-AlaAGC, tRNA:A:AGC:AE002602, tRNA[[Ala]], chr3L.trna45-AlaAGC, tRNA-Ala-AGC-2-1, tRNA:Ala-AGC-2-1, tRNA:CR32370, GCU" - CR32370 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065538 l(2)SH1068 lethal (2) SH1068 http://flybase.org/reports/FBgn0065538 gene - - - "l(2)SH1068, l(2)SH2 1068" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026015 Top3beta Topoisomerase 3beta http://flybase.org/reports/FBgn0026015 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000380, InterPro:IPR003601, InterPro:IPR003602, InterPro:IPR013497 DNA topoisomerase type I activity ; GO:0003917 | inferred from direct assay" DNA topological change ; GO:0006265 | inferred from direct assay positive regulation of synapse assembly ; GO:0051965 | inferred from mutant phenotype - "topo III[beta], top3[beta], TOP3, Top3beta, Top3, CG3458, Topo IIIbeta, top3beta, top3, dTop3beta" "IPR000380:DNA topoisomerase, type IA, IPR003601:DNA topoisomerase, type IA, domain 2, IPR003602:DNA topoisomerase, type IA, DNA-binding domain, IPR006171:TOPRIM domain, IPR013497:DNA topoisomerase, type IA, central, IPR023405:DNA topoisomerase, type IA, core domain, IPR023406:DNA topoisomerase, type IA, active site, IPR034144:DNA topoisomerase 3-like, TOPRIM domain, IPR013825:DNA topoisomerase, type IA, central region, subdomain 2" CG3458 11-Aug-17 DroID_v2017_08 "Drer\top3b, Drer\top3a" Scer\TOP3 Cele\Y48C3A.14 "Xtro\top3a, Xtro\top3b" "Mmus\Top3b, Mmus\Top3a" "Hsap\TOP3A, Hsap\PI4KA, Hsap\TOP3B" embryonic stage -- adult stage "neuroanatomy defective,viable,fertile" "embryonic/larval neuromuscular junction,NMJ bouton" FBgn0001016 fs(3)A7 female sterile (3) A7 http://flybase.org/reports/FBgn0001016 - gene - - - fs(3)A7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0062610 Mod(var)1317 Mod(var)1317 http://flybase.org/reports/FBgn0062610 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1317, Mod(var)1317" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0067727 mez mertz http://flybase.org/reports/FBgn0067727 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mez - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "egg,germline clone" FBgn0265954 CR44741 - http://flybase.org/reports/FBgn0265954 non_protein_coding_gene - - - CR44741 - CR44741 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004130 l(2)43Da lethal (2) 43Da http://flybase.org/reports/FBgn0004130 - gene - - - "43Da, l(2)43Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262779 Su(E1)-M - http://flybase.org/reports/FBgn0262779 gene - - - Su(E1)-M - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039593 Sid Stress induced DNase http://flybase.org/reports/FBgn0039593 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 deoxyribonuclease activity ; GO:0004536 | inferred from direct assay ribonuclease activity ; GO:0004540 | inferred from direct assay" response to bacterium ; GO:0009617 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype nucleic acid phosphodiester bond hydrolysis ; GO:0090305 | inferred from direct assay apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 response to paraquat ; GO:1901562 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG9989, Sid, sid" IPR001604:DNA/RNA non-specific endonuclease CG9989 11-Aug-17 DroID_v2017_08 "Drer\LOC100333474, Drer\endog, Drer\LOC103910196" Scer\NUC1 Cele\cps-6 - Mmus\Endog Hsap\ENDOG FBgn0264916 CR44107 - http://flybase.org/reports/FBgn0264916 non_protein_coding_gene - - - CR44107 - CR44107 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038773 CG10887 - http://flybase.org/reports/FBgn0038773 protein_coding_gene RNA polymerase II C-terminal domain phosphoserine binding ; GO:1990269 | inferred from biological aspect of ancestor with PANTHER:PTN000567381 histone modification ; GO:0016570 | inferred from electronic annotation with InterPro:IPR007149 positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from biological aspect of ancestor with PANTHER:PTN000567381 Cdc73/Paf1 complex ; GO:0016593 | inferred from electronic annotation with InterPro:IPR007149 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000567381 CG10887 IPR007149:Leo1-like protein CG10887 11-Aug-17 DroID_v2017_08 Drer\leo1 Scer\LEO1 Cele\leo-1 Xtro\leo1 Mmus\Leo1 Hsap\LEO1 viable DRSC27820 K 0.068846572 -1.153143284 0.082754422 0.322834243 -2.403463983 -0.65468178 FBgn0019819 ecp eclipse http://flybase.org/reports/FBgn0019819 - gene - - - "ecl, ecp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,eye color defective" pigment cell FBgn0058170 CG40170 - http://flybase.org/reports/FBgn0058170 protein_coding_gene - - - CG40170 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029711 Usf Usf http://flybase.org/reports/FBgn0029711 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 E-box binding ; GO:0070888 | inferred from direct assay - - "DmUsf, CG17592, Dm Usf, Usf, dUSF, dUSF2, bHLHb13" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG17592 11-Aug-17 DroID_v2017_08 "Drer\mitfb, Drer\tfeb, Drer\srebf2, Drer\mitfa, Drer\usf1, Drer\usf1l, Drer\usf2" "Scer\HMS1, Scer\INO4, Scer\RTG3, Scer\CBF1" "Cele\hlh-30, Cele\mxl-1, Cele\sbp-1" "Xtro\srebf2, Xtro\usf1, Xtro\usf2" "Mmus\Mitf, Mmus\Srebf1, Mmus\Srebf2, Mmus\Tfeb, Mmus\Usf1, Mmus\Usf2, Mmus\Tfe3" "Hsap\TFEB, Hsap\SREBF2, Hsap\USF2, Hsap\USF1, Hsap\MITF" viable FBgn0002939 ninaD neither inactivation nor afterpotential D http://flybase.org/reports/FBgn0002939 "FBgn0032662, FBgn0051783" protein_coding_gene scavenger receptor activity ; GO:0005044 | inferred from sequence or structural similarity inferred from mutant phenotype "phototransduction ; GO:0007602 | inferred from mutant phenotype phototransduction, UV ; GO:0007604 | inferred from mutant phenotype phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype carotenoid transport ; GO:0046867 | inferred from sequence or structural similarity inferred from mutant phenotype" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "CG5750, CG31783, ninaD, NINAD" IPR002159:CD36 family CG31783 11-Aug-17 DroID_v2017_08 "Drer\scarb2, Drer\cd36, Drer\LOC564077, Drer\scarb1" - "Cele\scav-3, Cele\scav-5, Cele\scav-1, Cele\scav-2" "Xtro\scarb2, Xtro\scarb1, Xtro\cd36" "Mmus\Scarb2, Mmus\Cd36, Mmus\Scarb1" "Hsap\CD36, Hsap\SCARB2, Hsap\SCARB1" "neurophysiology defective,viable" photoreceptor cell FBgn0067769 glissade glissade http://flybase.org/reports/FBgn0067769 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "gls, glissade" - - 11-Aug-17 DroID_v2017_08 - - - - - - "nurse cell,germline clone,egg chamber" FBgn0001786 l(1)M84 lethal (1) M84 http://flybase.org/reports/FBgn0001786 - gene - - - l(1)M84 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0038342 B9d1 B9d1 http://flybase.org/reports/FBgn0038342 protein_coding_gene - cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern MKS complex ; GO:0036038 | inferred from sequence or structural similarity with MGI:MGI:1351471 ciliary transition zone ; GO:0035869 | inferred from direct assay "CG14870, B9d1, B9D1" IPR010796:B9 domain CG14870 11-Aug-17 DroID_v2017_08 "Drer\b9d2, Drer\b9d1, Drer\mks1" - "Cele\mks-1, Cele\mksr-1, Cele\mksr-2" "Xtro\b9d1, Xtro\mks1, Xtro\b9d2" "Mmus\Mks1, Mmus\B9d2, Mmus\B9d1" "Hsap\B9D2, Hsap\MKS1, Hsap\B9D1" viable FBgn0011698 prp prickly pear http://flybase.org/reports/FBgn0011698 - gene - - - prp - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266442 CG45072 - http://flybase.org/reports/FBgn0266442 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45072, CG18682" - CG45072 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040708 CG15421 - http://flybase.org/reports/FBgn0040708 protein_coding_gene - - - CG15421 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033669 PI31 Proteasome inhibitor 31 kDa http://flybase.org/reports/FBgn0033669 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype male gonad development ; GO:0008584 | inferred from mutant phenotype proteasome assembly ; GO:0043248 | inferred from direct assay male meiosis ; GO:0007140 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from direct assay inferred from mutant phenotype inferred from genetic interaction with Prosβ6 inferred from genetic interaction with Prosβ2 sperm individualization complex ; GO:0070864 | inferred from direct assay "CG8979, cg8979, DmPI31, 8979, PI31, dmPI31" "IPR021625:PI31 proteasome regulator, N-terminal" CG8979 11-Aug-17 DroID_v2017_08 Drer\psmf1 - - - Mmus\Psmf1 Hsap\PSMF1 "meiotic cell cycle defective,lethal,recessive,melanotic mass phenotype,body size defective,developmental rate defective,visible,body color defective,partially lethal - majority die,some die during pupal stage" "male germline cyst,trichogen cell,mesothoracic tergum,wing,tarsal segment,arista" FBgn0061087 l(3)S011832 lethal (3) S011832 http://flybase.org/reports/FBgn0061087 gene - - - "0118/32, l(3)S011832" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0042701 CR12628 Microsomal glutathione S-transferase-like pseudogene http://flybase.org/reports/FBgn0042701 pseudogene_attribute - - - "CR12628, CT35150, CG12628, Mgstl-Psi" - CR12628 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017381 l(1)3-64 lethal (1) 3-64 http://flybase.org/reports/FBgn0017381 - gene - - - "3-64, l(1)3-64" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002733 E(spl)mbeta-HLH "Enhancer of split mbeta, helix-loop-helix" http://flybase.org/reports/FBgn0002733 - protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from expression pattern compound eye development ; GO:0048749 | traceable author statement - "CG14548, mbeta, HLHmbeta, E(spl)mbeta, E(spl)-mbeta, E(spl)mA, Dm-mA, E(Spl) HLH-Mbeta, Mbeta, E(spl) mbeta, E(spl)Mbeta, E(spl)-Mbeta, E(spl)beta, E(spl), HLH-mbeta, mA, HLHmA, E(Spl)mbeta, bHLHb34, m-beta, E(spl)mbeta}, E(spl)mbeta-HLH, mb, HLHMbeta, E(spl)mb" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG14548 11-Aug-17 DroID_v2017_08 "Drer\her7, Drer\LOC100149863, Drer\her12, Drer\her1, Drer\her6, Drer\hes6, Drer\bhlhe40, Drer\helt, Drer\her11, Drer\her9, Drer\her13, Drer\hey1, Drer\heyl, Drer\hey2, Drer\her8a, Drer\her4.2, Drer\her4.3, Drer\hes2.2, Drer\her15.1, Drer\her2, Drer\her4.4, Drer\her8.2, Drer\her15.2, Drer\her5, Drer\bhlhe41, Drer\her3, Drer\hes2.1" Scer\PHO4 "Cele\hlh-25, Cele\hlh-27, Cele\lin-22" "Xtro\hes4, Xtro\hes2, Xtro\hes7.1, Xtro\hey1, Xtro\hes6.2, Xtro\hey2, Xtro\hes6.1, Xtro\bhlhe41, Xtro\bhlhe40, Xtro\hes7.2, Xtro\hes1" "Mmus\Hes3, Mmus\Hes6, Mmus\Hey1, Mmus\Hey2, Mmus\Heyl, Mmus\Helt, Mmus\Bhlhe41, Mmus\Hes2, Mmus\Bhlhe40, Mmus\Hes5, Mmus\Hes1, Mmus\Hes7" "Hsap\HEYL, Hsap\HES6, Hsap\HELT, Hsap\BHLHE40, Hsap\HES5, Hsap\HES3, Hsap\HEY1, Hsap\HES7, Hsap\HES4, Hsap\HES1, Hsap\BHLHE41, Hsap\HES2, Hsap\HEY2" "visible,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" "scutellar bristle,anterior crossvein,wing vein,macrochaeta,microchaeta,wing vein L5,wing margin bristle,scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutum & macrochaetah-1J3,wing & macrochaetaptc-559.1,scutum & macrochaetaptc-559.1,ectopic" FBgn0267885 CR46173 - http://flybase.org/reports/FBgn0267885 pseudogene_attribute - - - "CR46173, CG12717-related" - CR46173 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061033 l(3)S023943 lethal (3) S023943 http://flybase.org/reports/FBgn0061033 gene - - - "0239/43, l(3)S023943" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028580 ms(2)35Bi male sterile (2) 35Bi http://flybase.org/reports/FBgn0028580 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(2)35Bi - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0005043 E(var)29BD Enhancer of variegation 29BD http://flybase.org/reports/FBgn0005043 - gene - - - E(var)29BD - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005660 Ets21C Ets at 21C http://flybase.org/reports/FBgn0005660 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418, InterPro:IPR003118 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000218930" dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 "CG2914, ets21C, ets21c, Ets, D-ets-6, ETS6, D-Ets-6, Ets6, Ets21C, D-Ets6" "IPR000418:Ets domain, IPR003118:Pointed domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR013761:Sterile alpha motif/pointed domain" CG2914 11-Aug-17 DroID_v2017_08 "Drer\LOC100537796, Drer\erfl3, Drer\elk3, Drer\etv5a, Drer\fev, Drer\erf, Drer\erfl1, Drer\elk1, Drer\elk4, Drer\etv5b, Drer\gabpa, Drer\etv1, Drer\etv4, Drer\etv2, Drer\erg, Drer\fli1a, Drer\ets2, Drer\fli1b" - "Cele\ets-5, Cele\ets-4, Cele\elf-1, Cele\ast-1" "Xtro\elk3, Xtro\etv1, Xtro\etv3, Xtro\erg, Xtro\ets2, Xtro\ets1, Xtro\gabpa, Xtro\erf, Xtro\elk1, Xtro\etv2, Xtro\fli1, Xtro\elk4" "Mmus\Elk1, Mmus\Etv1, Mmus\Fev, Mmus\Etv3, Mmus\Etv5, Mmus\Erg, Mmus\Gabpa, Mmus\Erf, Mmus\Fli1, Mmus\Etv4, Mmus\Elk4, Mmus\Etv2, Mmus\Ets2, Mmus\Ets1, Mmus\Elk3" "Hsap\FLI1, Hsap\ETV4, Hsap\ETV3L, Hsap\ETV5, Hsap\ETV1, Hsap\ERG, Hsap\ETS1, Hsap\ETV3, Hsap\ETS2, Hsap\ELK4, Hsap\ETV2, Hsap\ERF, Hsap\ELK3, Hsap\FEV, Hsap\GABPA, Hsap\ELK1" embryonic stage ventral nerve cord | restricted

"viable,fertile" FBgn0263980 CG43729 - http://flybase.org/reports/FBgn0263980 protein_coding_gene - intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 positive regulation of cell size ; GO:0045793 | inferred from genetic interaction with gig lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG43729, CG34318/CG34365/CG8179, CG34318, CG8179, CG30470, CG14163, CG34365, CG18625, CG12959, CG12958, CG43223, Dm_2R:47672, Dm_2R:47664, mdcds_11908" "IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001452:SH3 domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain" CG43729 11-Aug-17 DroID_v2017_08 "Drer\stac3, Drer\stac" - Cele\F19C7.8 "Xtro\stac3, Xtro\stac2" "Mmus\Stac2, Mmus\Stac3, Mmus\Stac" "Hsap\STAC2, Hsap\STAC3, Hsap\STAC" DRSC23183 K 1.706486097 1.875032981 FBgn0034452 Oseg6 Outer segment 6 http://flybase.org/reports/FBgn0034452 protein_coding_gene molecular_function ; GO:0003674 | no biological data available non-motile cilium assembly ; GO:1905515 | inferred from sequence or structural similarity with Oseg1 cilium assembly ; GO:0060271 | inferred from expression pattern intraciliary transport particle A ; GO:0030991 | inferred from sequence or structural similarity with HGNC:18340 non-motile cilium ; GO:0097730 | inferred from direct assay "OSEG6, CG11237, Oseg6, OSEG, Wdr19, IFT144, oseg6, WDR19" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR011990:Tetratricopeptide-like helical domain, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG11237 11-Aug-17 DroID_v2017_08 Drer\wdr19 - Cele\dyf-2 Xtro\wdr19 Mmus\Wdr19 "Hsap\IFT122, Hsap\IFT80, Hsap\WDR19" viable FBgn0045978 PdL2B1 PdL2B1 http://flybase.org/reports/FBgn0045978 gene - - - PdL2B1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,short lived,viable" FBgn0266235 CR44930 - http://flybase.org/reports/FBgn0266235 non_protein_coding_gene - - - "CR44930, lincRNA.697" - CR44930 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015942 ftz::prd ftz::prd http://flybase.org/reports/FBgn0015942 - engineered_fusion_gene - - - ftz::prd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023021 l(3)S001407b lethal (3) S001407b http://flybase.org/reports/FBgn0023021 - gene - - - "14/7, 0014/07, l(3)S001407, l(3)S001407b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037254 CG14651 - http://flybase.org/reports/FBgn0037254 protein_coding_gene microtubule motor activity ; GO:0003777 | inferred from electronic annotation with InterPro:IPR026983 microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR026983 - CG14651 "IPR026983:Dynein heavy chain, IPR013602:Dynein heavy chain, domain-2" CG14651 11-Aug-17 DroID_v2017_08 Drer\dnah1 - - - - - viable FBgn0040802 CG12329 - http://flybase.org/reports/FBgn0040802 protein_coding_gene - - - CG12329 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028681 SW140 SW140 http://flybase.org/reports/FBgn0028681 gene - - - SW140 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000973 fs(2)HO8 female sterile (2) HO8 http://flybase.org/reports/FBgn0000973 - gene - - - "fs(2)8B, fs(2)HO8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" ovary FBgn0032835 CG16772 - http://flybase.org/reports/FBgn0032835 protein_coding_gene - - - "anon-WO0138581.5, CG16772" - CG16772 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038849 CG7079 - http://flybase.org/reports/FBgn0038849 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CG7079, cg7079" IPR010562:Haemolymph juvenile hormone binding CG7079 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262109 CR42862 - http://flybase.org/reports/FBgn0262109 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR42862, CR32477, CG32477, anon-EST:fe1H7, CG13878, BcDNA:GH06422, CG16971" - CR42862 11-Aug-17 DroID_v2017_08 - - - - - - DRSC36563 EK -0.113180111 0.151278683 1.758689469 0.85449034 3.083665337 -0.224693987 FBgn0003167 pur purplish ruby http://flybase.org/reports/FBgn0003167 - gene - - - pur - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,recessive,eye color defective,visible" pigment cell FBgn0031417 CG3597 - http://flybase.org/reports/FBgn0031417 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR000683 - - "BVRA, CG3597" "IPR000683:Oxidoreductase, N-terminal, IPR016040:NAD(P)-binding domain" CG3597 11-Aug-17 DroID_v2017_08 "Drer\zgc:154075, Drer\dhdhl, Drer\zgc:101723, Drer\si:ch211-276f18.2" "Scer\YMR315W, Scer\GAL80" Cele\F53C11.1 "Xtro\dhdh, Xtro\gfod1" "Mmus\Gfod1, Mmus\Dhdh, Mmus\Blvra" "Hsap\GFOD1, Hsap\BLVRA, Hsap\DHDH" viable FBgn0065968 l(2)SH0007 lethal (2) SH0007 http://flybase.org/reports/FBgn0065968 gene - - - "l(2)SH0007, l(2)SH2 0007" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065935 l(2)SH0126 lethal (2) SH0126 http://flybase.org/reports/FBgn0065935 gene - - - "l(2)SH0126, l(2)SH2 0126" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020644 Lcp65Ab1 Lcp65Ab1 http://flybase.org/reports/FBgn0020644 "FBgn0002536, FBgn0002540, FBgn0042117, FBgn0052400" protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence or structural similarity structural constituent of chitin-based larval cuticle ; GO:0008010 | non-traceable author statement structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model larval chitin-based cuticle development ; GO:0008363 | non-traceable author statement chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular region ; GO:0005576 | non-traceable author statement extracellular matrix ; GO:0031012 | inferred from sequence model "Lcp-b, Lcp65A-b, Lcp5, Lcp65Ab, Lcp-b1, LCP5, Lcp65Abl, LCP-5, Rho, L[[3]]CP5, CP5, LCP10, Lcp10, DCP-alpha, CG18776, CG32400, Lcp65Ab1, LCP65Ab1" IPR000618:Insect cuticle protein CG32400 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\math-34, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " embryonic stage , larval stage " "electrophoretic variant,fast,slow" FBgn0026355 Su(SuRaf1)12 Su(SuRaf1)12 http://flybase.org/reports/FBgn0026355 - gene - - - "Su[Su(Raf)1]12, Su(SuRaf1)12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262965 CR43276 - http://flybase.org/reports/FBgn0262965 pseudogene_attribute - - - CR43276 - CR43276 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034061 Ufc1 Ubiquitin-fold modifier conjugating enzyme 1 http://flybase.org/reports/FBgn0034061 protein_coding_gene UFM1 transferase activity ; GO:0071568 | inferred from biological aspect of ancestor with PANTHER:PTN000308898 locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype protein K69-linked ufmylation ; GO:1990592 | inferred from biological aspect of ancestor with PANTHER:PTN000308898 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000308898 "CG8386, Ufc1, dUFC1" "IPR014806:Ubiquitin-fold modifier-conjugating enzyme 1, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG8386 11-Aug-17 DroID_v2017_08 Drer\ufc1 - Cele\ufc-1 Xtro\ufc1 Mmus\Ufc1 Hsap\UFC1 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,tormogen cell" FBgn0085410 TrissinR Trissin receptor http://flybase.org/reports/FBgn0085410 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled peptide receptor activity ; GO:0008528 | inferred from physical interaction with Trissin peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN001202348 G-protein coupled peptide receptor activity ; GO:0008528 | inferred from sequence or structural similarity with TkR99D cellular response to hormone stimulus ; GO:0032870 | inferred from biological aspect of ancestor with PANTHER:PTN001202348 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model response to peptide ; GO:1901652 | inferred from biological aspect of ancestor with PANTHER:PTN001202348 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with TkR99D integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with TkR99D "CG14004, CG14003, CG14002, anon-WO0170980.173, anon-WO0170980.172, CG31645, TrissinR, CG34381" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG34381 11-Aug-17 DroID_v2017_08 "Drer\npffr2a, Drer\LOC100535965" - "Cele\npr-20, Cele\npr-21, Cele\npr-3" - Mmus\Oprd1 Hsap\NPBWR1 viable DRSC02335 IE -0.38479675 -3.247420011 -0.551870295 -1.878198683 -1.222471429 0.039422164 FBgn0004789 Indnc In dunce http://flybase.org/reports/FBgn0004789 - gene - - - "indnc, Indnc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005229 l(3)R4 lethal of Roberts 4 http://flybase.org/reports/FBgn0005229 - gene - - - "l(3)B4, l(3)R4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive" FBgn0266346 CngB Cyclic nucleotide-gated ion channel subunit B http://flybase.org/reports/FBgn0266346 protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 intracellular cyclic nucleotide activated cation channel activity ; GO:0005221 | inferred from direct assay intracellular cyclic nucleotide activated cation channel activity ; GO:0005221 | inferred from sequence or structural similarity with CngA transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 cation transport ; GO:0006812 | inferred from sequence or structural similarity with CngA regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 cation transport ; GO:0006812 | inferred by curator from GO:0005221 cyclic-nucleotide-mediated signaling ; GO:0019935 | inferred from sequence or structural similarity with CngA intracellular cyclic nucleotide activated cation channel complex ; GO:0017071 | inferred from sequence or structural similarity with CngA integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 "CG17922, CngB, dmCNGB, dCNCbeta, Cncbeta" "IPR000595:Cyclic nucleotide-binding domain, IPR005821:Ion transport domain, IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR014710:RmlC-like jelly roll fold" CG17922 11-Aug-17 DroID_v2017_08 "Drer\cngb3.1, Drer\LOC103911065, Drer\cngb1a, Drer\LOC562466, Drer\cnga1, Drer\cnga4, Drer\si:dkey-22i16.2, Drer\cnga5" - "Cele\cng-2, Cele\tax-4, Cele\che-6, Cele\cng-3, Cele\cng-1, Cele\tax-2" "Xtro\cngb1, Xtro\cnga3, Xtro\cngb3, Xtro\cnga1, Xtro\cnga4" "Mmus\Cnga3, Mmus\Cnga4, Mmus\Cnga2, Mmus\Cngb1, Mmus\Cngb3" "Hsap\CNGA3, Hsap\CNGA2, Hsap\CNGB3, Hsap\CNGB1, Hsap\CNGA4" FBgn0067761 l(1)G0001 lethal (1) G0001 http://flybase.org/reports/FBgn0067761 gene - - - l(1)G0001 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0011637 l(3)Lak lethal(3)Laker http://flybase.org/reports/FBgn0011637 - gene - - - "l(3)Lkr, l(3)Lak" - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,dominant,lethal,recessive" FBgn0262577 CG43117 - http://flybase.org/reports/FBgn0262577 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43117 - CG43117 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030167 CG15252 - http://flybase.org/reports/FBgn0030167 protein_coding_gene - - - CG15252 IPR011990:Tetratricopeptide-like helical domain CG15252 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263940 BG00037 - http://flybase.org/reports/FBgn0263940 gene - - - BG00037 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0052774 Muc4B Mucin 4B http://flybase.org/reports/FBgn0052774 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model eggshell chorion assembly ; GO:0007306 | inferred from expression pattern inferred from genomic context extracellular matrix ; GO:0031012 | inferred from sequence model chorion ; GO:0042600 | inferred from genomic context "CG15575, CG15574, Muc4B, CG32774, muc4B" - CG32774 11-Aug-17 DroID_v2017_08 - - - - - Hsap\C11orf24 "lethal,partially lethal - majority die,visible" trichogen cell DRSC18063 IE -0.108804632 -1.83696519 -0.322308662 -1.842539069 1.230322538 0.938912377 FBgn0016877 l(2)39DEb lethal (2) 39DEb http://flybase.org/reports/FBgn0016877 - gene - - - "C87, l(2)39DEb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0086295 aspn aspiny http://flybase.org/reports/FBgn0086295 gene - filopodium assembly ; GO:0046847 | inferred from mutant phenotype - aspn - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite & filopodium & larva FBgn0037365 CG2104 - http://flybase.org/reports/FBgn0037365 protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 protein tyrosine phosphatase activator activity ; GO:0008160 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 mitotic spindle organization in nucleus ; GO:0030472 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 protein phosphatase type 2A complex ; GO:0000159 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 CG2104 "IPR004327:Phosphotyrosyl phosphatase activator, PTPA" CG2104 11-Aug-17 DroID_v2017_08 Drer\ppp2r4 "Scer\RRD2, Scer\RRD1" Cele\Y71H2AM.20 Xtro\ppp2r4 Mmus\Ptpa Hsap\PTPA viable FBgn0045972 PdL73A1 PdL73A1 http://flybase.org/reports/FBgn0045972 gene - - - PdL73A1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058192 CG40192 - http://flybase.org/reports/FBgn0058192 protein_coding_gene - - - CG40192 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032234 gny garnysstan http://flybase.org/reports/FBgn0032234 protein_coding_gene "dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity ; GO:0042281 | inferred from biological aspect of ancestor with PANTHER:PTN000275691 glucosyltransferase activity ; GO:0046527 | inferred from sequence or structural similarity with UniProtKB:Q9Y672" protein N-linked glycosylation ; GO:0006487 | inferred from sequence or structural similarity with UniProtKB:Q9Y672 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype protein N-linked glycosylation ; GO:0006487 | inferred from biological aspect of ancestor with PANTHER:PTN000275691 oligosaccharide-lipid intermediate biosynthetic process ; GO:0006490 | inferred from biological aspect of ancestor with PANTHER:PTN000275691 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000275691 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000005528 "gny, CG5091, Dalg6, alg6, dAlg6, Gny[" "IPR004856:Glycosyl transferase, ALG6/ALG8" CG5091 11-Aug-17 DroID_v2017_08 Drer\alg6 "Scer\ALG6, Scer\ALG8" "Cele\C08B11.8, Cele\C08H9.3" "Xtro\alg6, Xtro\bola2" "Mmus\Alg8, Mmus\Bola2, Mmus\Alg6" "Hsap\ALG6, Hsap\BOLA2, Hsap\BOLA2B" "lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable" "cephalopharyngeal skeleton,germline clone,embryonic/first instar larval cuticle,denticle" FBgn0065126 l(3)SH140 lethal (3) SH140 http://flybase.org/reports/FBgn0065126 gene - - - "l(3)SH140, l(2)SH3 140" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015962 l(2)46Cp lethal (2) 46Cp http://flybase.org/reports/FBgn0015962 - gene - - - "group 4, l(2)46Cp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040791 CG13697 - http://flybase.org/reports/FBgn0040791 protein_coding_gene - - - CG13697 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060375 l(3)S136414b lethal (3) S136414b http://flybase.org/reports/FBgn0060375 gene - - - "1364/14, l(3)S136414b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004978 ats abnormal tarsi http://flybase.org/reports/FBgn0004978 - gene - - - ats - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,female sterile,lethal,partially,some die during immature adult stage" "tarsal segment,tarsal segment 2,tarsal segment 3,tarsal segment 4,metatarsus,pretarsus" FBgn0267567 CR45907 - http://flybase.org/reports/FBgn0267567 non_protein_coding_gene - - - CR45907 - CR45907 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045975 PdL43C1 PdL43C1 http://flybase.org/reports/FBgn0045975 gene - - - PdL43C1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,short lived,recessive" FBgn0266317 CR44982 - http://flybase.org/reports/FBgn0266317 non_protein_coding_gene - - - CR44982 - CR44982 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259736 CG42390 - http://flybase.org/reports/FBgn0259736 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42390, CG5740, CG33334" - CG42390 11-Aug-17 DroID_v2017_08 - - - - Mmus\Tmf1 - FBgn0266646 CR45153 - http://flybase.org/reports/FBgn0266646 non_protein_coding_gene - - - CR45153 - CR45153 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015887 anon-6Ea anon-6Ea http://flybase.org/reports/FBgn0015887 - gene - - - anon-6Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033264 Nup50 Nucleoporin 50kD http://flybase.org/reports/FBgn0033264 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from mutant phenotype Ran GTPase binding ; GO:0008536 | inferred from biological aspect of ancestor with PANTHER:PTN000566730 protein binding ; GO:0005515 | inferred from physical interaction with Z600 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN000319227 chromatin ; GO:0000785 | inferred from mutant phenotype "Nup50, CG2158, nup50, Nup, NUP50" "IPR000156:Ran binding domain, IPR011993:PH domain-like, IPR015007:Nuclear pore complex, NUP2/50/61" CG2158 11-Aug-17 DroID_v2017_08 Drer\nup50 Scer\NUP2 Cele\npp-16 Xtro\nup50 Mmus\Nup50 Hsap\NUP50 "long lived,lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,trichogen cell,supernumerary,tormogen cell" FBgn0046661 anon-38C.43 anon-38C.43 http://flybase.org/reports/FBgn0046661 gene - - - "38C.43, anon-38C.43" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265734 CR44541 - http://flybase.org/reports/FBgn0265734 non_protein_coding_gene - - - CR44541 - CR44541 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036327 CG10748 - http://flybase.org/reports/FBgn0036327 protein_coding_gene L-malate dehydrogenase activity ; GO:0030060 | inferred from sequence or structural similarity with UniProtKB:P40926 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR015955 malate metabolic process ; GO:0006108 | inferred from electronic annotation with InterPro:IPR001252, InterPro:IPR010097 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P40926" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P40926 CG10748 "IPR001236:Lactate/malate dehydrogenase, N-terminal, IPR001252:Malate dehydrogenase, active site, IPR001557:L-lactate/malate dehydrogenase, IPR010097:Malate dehydrogenase, type 1, IPR015955:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR016040:NAD(P)-binding domain, IPR022383:Lactate/malate dehydrogenase, C-terminal" CG10748 11-Aug-17 DroID_v2017_08 Drer\mdh2 "Scer\MDH2, Scer\MDH1, Scer\MDH3" "Cele\mdh-1, Cele\mdh-2" Xtro\mdh2 Mmus\Mdh2 Hsap\MDH2 viable FBgn0031066 COX6B Cytochrome c oxidase subunit 6B http://flybase.org/reports/FBgn0031066 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with SGD:S000004028 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from sequence or structural similarity with SGD:S000004028 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with SGD:S000004028 "CcoVIb, CG14235, VIb, COXG, COX6B, CoVIb, Cox6b" "IPR003213:Cytochrome c oxidase, subunit VIb" CG14235 11-Aug-17 DroID_v2017_08 "Drer\cox6b2, Drer\coa6, Drer\cox6b1, Drer\si:ch73-152o7.1" Scer\COX12 Cele\Y71H2AM.5 "Xtro\cox6b1, Xtro\c19orf43, Xtro\coa6" "Mmus\2310036O22Rik, Mmus\Coa6, Mmus\Cox6b2, Mmus\Cox6b1" "Hsap\COX6B2, Hsap\COA6, Hsap\C19orf43, Hsap\COX6B1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" DRSC27409 IK -1.673770547 -1.792033676 -0.553467068 -0.198414073 0.610369889 1.561194718 FBgn0031070 CG12702 - http://flybase.org/reports/FBgn0031070 protein_coding_gene - - - "CG12702, lincRNA.1023" - CG12702 11-Aug-17 DroID_v2017_08 Drer\zgc:174160 - Cele\myo-5 Xtro\kiaa1524 Mmus\C330027C09Rik Hsap\KIAA1524 viable FBgn0082579 zwi zwirbel http://flybase.org/reports/FBgn0082579 gene - - - zwi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "mesoderm,presumptive embryonic/larval digestive system" FBgn0263353 CG11000 - http://flybase.org/reports/FBgn0263353 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cell differentiation ; GO:0045595 | inferred from biological aspect of ancestor with PANTHER:PTN001023612 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001023612 "CG11000, BcDNA:HL04389, CG31555" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG11000 11-Aug-17 DroID_v2017_08 "Drer\plekhb2, Drer\si:ch211-176g13.7, Drer\si:ch1073-83n3.2" - Cele\F38B7.3 - "Mmus\Plekhb2, Mmus\Plekhb1" "Hsap\PLEKHB2, Hsap\PLEKHB1" FBgn0028743 Dhit Double hit http://flybase.org/reports/FBgn0028743 protein_coding_gene G-protein alpha-subunit binding ; GO:0001965 | inferred from physical interaction with Gαo GDP-dissociation inhibitor activity ; GO:0005092 | inferred from direct assay GTPase activator activity ; GO:0005096 | inferred from direct assay positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 "EG:52C10.2, CG5036, Dhit, dhit" "IPR024066:RGS, subdomain 1, IPR016137:RGS domain" CG5036 11-Aug-17 DroID_v2017_08 "Drer\rgs6, Drer\rgs9b, Drer\rgs5b, Drer\si:ch211-117l17.6, Drer\rgs17, Drer\rgs19, Drer\rgs16, Drer\axin2, Drer\si:ch211-117l17.5, Drer\rgs11, Drer\grid2ipb, Drer\rgs12b, Drer\si:ch211-152p11.4, Drer\rgs4, Drer\rgs5a, Drer\rgs13, Drer\si:ch211-196h16.12, Drer\rgs18, Drer\rgs14b, Drer\rgs14a, Drer\axin1, Drer\rgs3a, Drer\rgs8, Drer\rgs1, Drer\rgs12a, Drer\rgs2, Drer\rgs20" "Scer\SST2, Scer\RGS2" "Cele\rgs-1, Cele\rgs-7, Cele\rgs-2" "Xtro\rgs2, Xtro\rgs1, Xtro\axin1, Xtro\rgs19, Xtro\rgs6, Xtro\rgs10, Xtro\rgs3, Xtro\cep112, Xtro\rgs17, Xtro\rgs20, Xtro\xarp, Xtro\rgs4, Xtro\rgs5, Xtro\rgs18, Xtro\rgs16" "Mmus\Rgs12, Mmus\Rgs13, Mmus\Rgs4, Mmus\Rgs21, Mmus\Rgs6, Mmus\Rgs8, Mmus\Rgs18, Mmus\Rgs7, Mmus\Rgs5, Mmus\Rgs20, Mmus\Axin2, Mmus\Axin1, Mmus\Rgs16, Mmus\Rgs17, Mmus\Rgs19, Mmus\Rgs9, Mmus\Rgs3, Mmus\Rgs10, Mmus\Rgs11, Mmus\Rgs2, Mmus\Rgs1, Mmus\Rgs14" "Hsap\RGS16, Hsap\RGS21, Hsap\RGS11, Hsap\RGS14, Hsap\RGS9, Hsap\RGS13, Hsap\RGS2, Hsap\RGS19, Hsap\RGS4, Hsap\RGS10, Hsap\RGS20, Hsap\RGS18, Hsap\RGS7, Hsap\RGS5, Hsap\RGS17, Hsap\RGS12, Hsap\AXIN2, Hsap\AXIN1, Hsap\RGS3, Hsap\RGS6, Hsap\RGS8, Hsap\RGS1" wing margin bristle FBgn0262778 Su(E1)-L - http://flybase.org/reports/FBgn0262778 gene - - - Su(E1)-L - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004576 Pig2 Pre-intermoult gene 2 http://flybase.org/reports/FBgn0004576 - gene - - - "Pig-2, pig2, Pig2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0054008 CG34008 - http://flybase.org/reports/FBgn0054008 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34008, BP1002" - CG34008 11-Aug-17 DroID_v2017_08 - - Cele\C56G2.5 - - - FBgn0025471 qkr58E-6 quaking related 58E-6 http://flybase.org/reports/FBgn0025471 - gene - - - "qrk58E-6, qkr58E-6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026747 anon-25D26Aa anon-25D26Aa http://flybase.org/reports/FBgn0026747 - gene - - - anon-25D26Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015352 anon-99Ca anon-99Ca http://flybase.org/reports/FBgn0015352 - gene - - - anon-99Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067103 G6.A G6.A http://flybase.org/reports/FBgn0067103 gene - - - "G6, G6.A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,partially lethal - majority die" chaeta FBgn0265439 orb2::Mmus\Cpeb2 - http://flybase.org/reports/FBgn0265439 engineered_fusion_gene - - - "orb2::Mmus\Cpeb2, orb2[orb1RBD]" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,learning defective,courtship behavior defective" FBgn0033169 CG11123 - http://flybase.org/reports/FBgn0033169 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001313 - - CG11123 "IPR001313:Pumilio RNA-binding repeat, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG11123 11-Aug-17 DroID_v2017_08 Drer\nop9 Scer\NOP9 Cele\ZK792.5 Xtro\nop9 Mmus\Nop9 Hsap\NOP9 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0259242 CG42340 - http://flybase.org/reports/FBgn0259242 protein_coding_gene potassium channel activity ; GO:0005267 | inferred from electronic annotation with InterPro:IPR003280 molecular_function ; GO:0003674 | no biological data available potassium ion transmembrane transport ; GO:0071805 | inferred from electronic annotation with InterPro:IPR003280 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003280 "CG42340, CG12543, CG3367" "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain, IPR014710:RmlC-like jelly roll fold" CG42340 11-Aug-17 DroID_v2017_08 "Drer\kcnk10b, Drer\kcnk6, Drer\kcnk18, Drer\kcnk5b, Drer\kcnk10a, Drer\kcnk5a, Drer\kcnk1b, Drer\kcnk7, Drer\kcnk2a, Drer\kcnk1a" Scer\TOK1 "Cele\twk-48, Cele\twk-39" "Xtro\kcnk1, Xtro\kcnk2, Xtro\LOC100486031, Xtro\kcnk5, Xtro\kcnk16, Xtro\kcnk6, Xtro\kcnk18, Xtro\kcnk4, Xtro\kcnk7, Xtro\kcnk10" "Mmus\Kcnk16, Mmus\Kcnk1, Mmus\Kcnk4, Mmus\Kcnk7, Mmus\Kcnk10, Mmus\Kcnk6, Mmus\Kcnk5, Mmus\Kcnk18, Mmus\Kcnk2" "Hsap\KCNK6, Hsap\KCNK10, Hsap\KCNK2, Hsap\KCNK4, Hsap\KCNK1, Hsap\KCNK18, Hsap\KCNK7, Hsap\KCNK16, Hsap\KCNK5, Hsap\KCNK17" DRSC18305 E -1.417026173 0.677930667 -0.240748222 1.581250051 -0.008698845 0.366282309 FBgn0016030 l(3)9D4 lethal (3) 9D4 http://flybase.org/reports/FBgn0016030 - gene - - - l(3)9D4 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260491 l(3)3425 - http://flybase.org/reports/FBgn0260491 gene - axonogenesis ; GO:0007409 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - l(3)3425 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,axon,dendrite" FBgn0025457 Bub3 Bub3 http://flybase.org/reports/FBgn0025457 - protein_coding_gene - mitotic spindle assembly checkpoint ; GO:0007094 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "Dmbub3, bub3, dBUB3, CG7581, Bub3, BUB3" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR020472:G-protein beta WD-40 repeat, IPR019775:WD40 repeat, conserved site" CG7581 11-Aug-17 DroID_v2017_08 Drer\bub3 "Scer\BUB3, Scer\GLE2" "Cele\F47D12.9, Cele\bub-3" Xtro\bub3 Mmus\Bub3 Hsap\BUB3 " adult stage | male , larval stage " " spermatocyte

, neuroblast

" "viable,visible" trichogen cell FBgn0019883 anon-64Ea anon-64Ea http://flybase.org/reports/FBgn0019883 - gene - - - anon-64Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084551 Swg Swing http://flybase.org/reports/FBgn0084551 gene - - - Swg - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,dominant,heat sensitive,neurophysiology defective,recessive" "indirect flight muscle,heat sensitive" FBgn0026616 alpha-Man-IIb alpha-Mannosidase class II b http://flybase.org/reports/FBgn0026616 - protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR015341 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from direct assay mannosyl-oligosaccharide 1,6-alpha-mannosidase activity ; GO:0052767 | inferred from direct assay" mannose metabolic process ; GO:0006013 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype protein deglycosylation ; GO:0006517 | inferred from mutant phenotype N-glycan processing ; GO:0006491 | inferred from mutant phenotype encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000176398 "Man'ase, DM-GII.2, GTD#24/1, alpha-M-II, CG4606, alpha-Man-IIb, alpha-Man-II b, ManIIb, GM, dGMIIb" "IPR000602:Glycoside hydrolase family 38, N-terminal domain, IPR011013:Galactose mutarotase-like domain, IPR011682:Glycosyl hydrolase family 38, C-terminal, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR015341:Glycoside hydrolase family 38, central domain, IPR027291:Glycoside hydrolase 38/57, N-terminal domain, IPR028995:Glycoside hydrolase families 57/38, central domain" CG4606 11-Aug-17 DroID_v2017_08 "Drer\man2a2, Drer\man2b2, Drer\man2b1" - "Cele\aman-2, Cele\aman-3" "Xtro\man2b2, Xtro\man2b1, Xtro\man2a1, Xtro\man2a2" "Mmus\Man2b2, Mmus\Man2b1, Mmus\Man2a2, Mmus\Man2a1" "Hsap\MAN2B2, Hsap\MAN2A2, Hsap\MAN2B1, Hsap\MAN2A1" "lethal,recessive,immune response defective,viable" FBgn0040532 CG8369 - http://flybase.org/reports/FBgn0040532 protein_coding_gene - "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - "anon-EST:Posey161, BcDNA:GH11984, CG8369" IPR002350:Kazal domain CG8369 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025132 su(RpII140[Z36])S15 su(RpII140[Z36])S15 http://flybase.org/reports/FBgn0025132 - gene - - - "Z36[S15], su(RpII140[Z36])S15" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031980 RpL36A Ribosomal protein L36A http://flybase.org/reports/FBgn0031980 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000552 structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000552, InterPro:IPR011332 cytoplasmic translation ; GO:0002181 | traceable author statement" ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000552 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG7424, anon-EST:fe1B2, RpL36A" "IPR011332:Zinc-binding ribosomal protein, IPR000552:Ribosomal protein L44e" CG7424 11-Aug-17 DroID_v2017_08 Drer\rpl36a "Scer\RPL42B, Scer\RPL42A" Cele\rpl-36.A Xtro\rpl36a "Mmus\Rpl36a, Mmus\Rpl36al" "Hsap\RPL36AL, Hsap\RPL36A, Hsap\RPL36A-HNRNPH2" lethal DRSC03055 IEK -1.798113552 -0.959610069 0.721300706 -3.360836949 0.408761397 4.045339765 FBgn0050488 antr antares http://flybase.org/reports/FBgn0050488 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sperm storage ; GO:0046693 | inferred from mutant phenotype negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "CG30488, antr" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG30488 11-Aug-17 DroID_v2017_08 "Drer\LOC100536500, Drer\crispld1b, Drer\r3hdml, Drer\crispld1a, Drer\glipr2l, Drer\glipr2, Drer\pi15b, Drer\pi15a, Drer\glipr1b, Drer\crispld2" "Scer\PRY3, Scer\PRY1, Scer\PRY2" "Cele\scl-20, Cele\scl-1, Cele\scl-10, Cele\scl-6, Cele\scl-23, Cele\vap-2" "Xtro\crisp1, Xtro\crisp2, Xtro\crispld2, Xtro\glipr2, Xtro\crisp3, Xtro\MGC108118, Xtro\r3hdml" "Mmus\Glipr1l1, Mmus\Pi16, Mmus\Crispld2, Mmus\Glipr2, Mmus\Clec18a, Mmus\Crisp1, Mmus\Glipr1, Mmus\Crisp4, Mmus\R3hdml, Mmus\Pi15, Mmus\Glipr1l2, Mmus\Crispld1, Mmus\Crisp2, Mmus\Crisp3" "Hsap\CRISP2, Hsap\PI16, Hsap\CRISPLD1, Hsap\CRISPLD2, Hsap\PI15, Hsap\CLEC18B, Hsap\GLIPR1, Hsap\GLIPR1L2, Hsap\GLIPR2, Hsap\GLIPR1L1, Hsap\CLEC18A, Hsap\R3HDML, Hsap\CRISP1, Hsap\CLEC18C" "mating behavior defective,female limited,female semi-fertile,viable" seminal receptacle FBgn0027585 CG8740 - http://flybase.org/reports/FBgn0027585 - protein_coding_gene - - - "BcDNA:GH05582, CG8740" - CG8740 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,planar polarity defective" trichogen cell FBgn0045979 PdL14B1 PdL14B1 http://flybase.org/reports/FBgn0045979 gene - - - PdL14B1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,short lived,recessive" FBgn0259541 GG01233 - http://flybase.org/reports/FBgn0259541 gene - - - GG01233 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0000325 clo close down http://flybase.org/reports/FBgn0000325 - gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - clo - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0001584 l(1)carot1 lethal (1) carot1 http://flybase.org/reports/FBgn0001584 - gene - - - l(1)carot1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004387 Klp98A Kinesin-like protein at 98A http://flybase.org/reports/FBgn0004387 - protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 phosphatidylinositol phosphate binding ; GO:1901981 | inferred from sequence or structural similarity with HGNC:15869 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 early endosome to late endosome transport ; GO:0045022 | inferred from sequence or structural similarity with HGNC:15869 kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 endosome ; GO:0005768 | inferred from sequence or structural similarity with HGNC:15869 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "CG5658, DmKlp98A, KLP98A, KLP6, Klp6, Klp98A, DmSNX23, KIF 16A, Klp98a, KIF16A/B" "IPR001683:Phox homologous domain, IPR001752:Kinesin motor domain, IPR008984:SMAD/FHA domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5658 11-Aug-17 DroID_v2017_08 "Drer\si:rp71-84d9.2, Drer\kif13ba, Drer\kif1c, Drer\kif14, Drer\kif13bb, Drer\kif1ab, Drer\kif16ba, Drer\kif1aa, Drer\kif16bb, Drer\stard9" "Scer\CIN8, Scer\SMY1, Scer\KIP1" - "Xtro\kif1a, Xtro\kif13b, Xtro\kif14, Xtro\kif1b, Xtro\kif1c, Xtro\kif16b" "Mmus\Kif16b, Mmus\Kif13b, Mmus\Kif1a, Mmus\Kif13a, Mmus\Gm1305, Mmus\Kif14, Mmus\Kif1b, Mmus\Kif1c, Mmus\Stard9" "Hsap\KIF13B, Hsap\KIF1B, Hsap\KIF1C, Hsap\KIF14, Hsap\KIF13A, Hsap\STARD9, Hsap\KIF1A, Hsap\KIF16B" viable FBgn0033802 CG17724 - http://flybase.org/reports/FBgn0033802 protein_coding_gene - - - "CG4037, CG17724a, CG17724" - CG17724 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0262275 mir-2280 mir-2280 stem loop http://flybase.org/reports/FBgn0262275 miRNA_gene - - - "mir-2280, CR42982, miR-2280, dme-mir-2280" - CR42982 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032511 ND-B22 NADH dehydrogenase (ubiquinone) B22 subunit http://flybase.org/reports/FBgn0032511 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:Q9Y6M9 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:Q9Y6M9" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000305443 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:Q9Y6M9 "NI2M, ND-B22, CG9306" IPR033034:NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 CG9306 11-Aug-17 DroID_v2017_08 Drer\ndufb9 - Cele\C16A3.5 Xtro\ndufb9 Mmus\Ndufb9 Hsap\NDUFB9 viable DRSC03193 K 0.471901099 -1.133314152 -1.079859272 0.820150589 1.603360279 -0.383777935 FBgn0030939 CG15041 - http://flybase.org/reports/FBgn0030939 protein_coding_gene - - - CG15041 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011171 l(1)291-7 lethal (1) 291-7 http://flybase.org/reports/FBgn0011171 FBgn0010199 gene - - - "291-7, l(1)291-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266386 insc::pins - http://flybase.org/reports/FBgn0266386 engineered_fusion_gene - - - "insc::raps, insc::pins" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038797 Dic2 Dicarboxylate carrier 2 http://flybase.org/reports/FBgn0038797 protein_coding_gene succinate transmembrane transporter activity ; GO:0015141 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transmembrane transporter activity ; GO:0015117 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 phosphate transmembrane transporter activity ; GO:1901677 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 oxaloacetate transmembrane transporter activity ; GO:0015131 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transporter activity ; GO:0015140 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 oxaloacetate transport ; GO:0015729 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 sulfate transport ; GO:0008272 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transport ; GO:0015709 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 succinate transmembrane transport ; GO:0071422 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 phosphate ion transmembrane transport ; GO:0035435 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transport ; GO:0071423 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG4323, Dic2, DmDic2p" "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG4323 11-Aug-17 DroID_v2017_08 "Drer\slc25a14, Drer\mrpl12, Drer\slc25a11, Drer\ucp2, Drer\si:ch1073-100f3.2, Drer\slc25a10" Scer\DIC1 "Cele\ucp-4, Cele\slc-25A10, Cele\mrpl-12" "Xtro\slc25a27, Xtro\rangrf, Xtro\ucp1, Xtro\ucp2, Xtro\slc25a30, Xtro\slc25a10" "Mmus\Slc25a11, Mmus\Ucp1, Mmus\Slc25a27, Mmus\Slc25a10, Mmus\Slc25a30, Mmus\Ucp2, Mmus\Slc25a14, Mmus\Mrpl12, Mmus\Ucp3" "Hsap\UCP2, Hsap\SLC25A10, Hsap\UCP1, Hsap\UCP3, Hsap\SLC25A14, Hsap\MRPL12, Hsap\SLC25A11, Hsap\SLC25A30, Hsap\SLC25A27" FBgn0065267 l(2)SH2067 lethal (2) SH2067 http://flybase.org/reports/FBgn0065267 gene - - - "l(2)SH2067, l(2)SH2 2067" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024321 NK7.1 NK7.1 http://flybase.org/reports/FBgn0024321 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG8524, NK7.1, NK-7.1" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG8524 11-Aug-17 DroID_v2017_08 "Drer\hmx2, Drer\hmx1, Drer\hmx3a, Drer\gbx2, Drer\pou5f3, Drer\hhex, Drer\pou2f3, Drer\tlx3b, Drer\barhl1a, Drer\gbx1, Drer\nkx3-1, Drer\hmx4" - "Cele\mls-2, Cele\ceh-62, Cele\ceh-9" "Xtro\hmx2, Xtro\gbx2.1, Xtro\hmx3, Xtro\ventx1.2, Xtro\hmx1, Xtro\gbx2.2" "Mmus\Nobox, Mmus\Gbx1, Mmus\Hmx2, Mmus\Nkx3-1, Mmus\Hmx1, Mmus\Hmx3, Mmus\Gbx2" "Hsap\NKX3-1, Hsap\HMX1, Hsap\HMX2, Hsap\GBX1, Hsap\HMX3, Hsap\GBX2" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035428 CG14960 - http://flybase.org/reports/FBgn0035428 protein_coding_gene - - - CG14960 - CG14960 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025487 l(3)82Ea lethal (3) 82Ea http://flybase.org/reports/FBgn0025487 - gene - - - l(3)82Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019761 l(1)72 lethal (1) 72 http://flybase.org/reports/FBgn0019761 - gene - - - l(1)72 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266525 CG45092 - http://flybase.org/reports/FBgn0266525 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45092 - CG45092 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028612 l(2)W13 lethal (2) W13 http://flybase.org/reports/FBgn0028612 gene - - - "l(2R)W13, l(2)W13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041749 l(1)A106.1F1 lethal (1) A106.1F1 http://flybase.org/reports/FBgn0041749 gene - - - "A106.1F1.L, l(1)A106.1F1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264086 CG43755 - http://flybase.org/reports/FBgn0264086 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43755, CG31920, NEST:bs21f09, BcDNA:GH10778, anon-WO0140519.62, CG33992, NEST:bs23f04" - CG43755 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265692 CR44499 - http://flybase.org/reports/FBgn0265692 non_protein_coding_gene - - - "lincRNA.956, CR44499" - CR44499 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001783 l(1)M77 lethal (1) M77 http://flybase.org/reports/FBgn0001783 - gene - - - l(1)M77 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011631 l(2)T57d13 lethal (2) T57d13 http://flybase.org/reports/FBgn0011631 FBgn0005177 gene - - - l(2)T57d13 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002893 mus207 mutagen-sensitive 207 http://flybase.org/reports/FBgn0002893 - gene - double-strand break repair ; GO:0006302 | inferred from mutant phenotype - mus207 - - 11-Aug-17 DroID_v2017_08 - - - - - - "DNA repair defective,chemical sensitive,radiation sensitive,recessive" FBgn0053475 CG33475 - http://flybase.org/reports/FBgn0053475 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33475 IPR010512:Protein of unknown function DUF1091 CG33475 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001554 l(1)19Ad lethal (1) 19Ad http://flybase.org/reports/FBgn0001554 - gene - - - l(1)19Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264983 CR44134 - http://flybase.org/reports/FBgn0264983 non_protein_coding_gene - - - CR44134 - CR44134 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266728 CR45201 - http://flybase.org/reports/FBgn0266728 non_protein_coding_gene - - - CR45201 - CR45201 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266176 pre-mod(mdg4)-J - http://flybase.org/reports/FBgn0266176 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-J, CG44882" "IPR007588:Zinc finger, FLYWCH-type" CG44882 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Flywch2, Mmus\Flywch1" - FBgn0264617 CR43957 - http://flybase.org/reports/FBgn0264617 non_protein_coding_gene - - - "CR43957, Mgn00541" - CR43957 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069115 mus215 mutagen-sensitive 215 http://flybase.org/reports/FBgn0069115 gene - - - mus215 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive,female fertile,meiotic cell cycle defective,female" FBgn0065355 l(2)SH1767 lethal (2) SH1767 http://flybase.org/reports/FBgn0065355 gene - - - "l(2)SH1767, l(2)SH2 1767" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267697 CR46033 - http://flybase.org/reports/FBgn0267697 non_protein_coding_gene - - - CR46033 - CR46033 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052802 CG32802 - http://flybase.org/reports/FBgn0052802 protein_coding_gene - - - CG32802 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC25226 K -0.421410809 0.073822446 -0.85698047 0.148434421 -0.186454721 -1.596951708 FBgn0005214 l(3)ET5 lethal Elaine Tasaka 5 http://flybase.org/reports/FBgn0005214 - gene - - - l(3)ET5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cold sensitive,heat sensitive,male sterile" FBgn0035779 CG8562 - http://flybase.org/reports/FBgn0035779 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "CT15463, CG8562" "IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide, IPR000834:Peptidase M14, carboxypeptidase A" CG8562 11-Aug-17 DroID_v2017_08 "Drer\cpa2, Drer\cpb1, Drer\cpa1, Drer\cpa5, Drer\cpo, Drer\cpb2, Drer\cpa4, Drer\cpa6" Scer\ECM14 "Cele\Y47G6A.19, Cele\Y18H1A.9, Cele\ZC434.9, Cele\suro-1, Cele\T06A4.1, Cele\T06A4.3, Cele\F02D8.4, Cele\W01A8.6, Cele\Y59C2A.1" "Xtro\cpa3, Xtro\cpb2, Xtro\cpa1, Xtro\cpo, Xtro\cpb1" "Mmus\Cpa4, Mmus\Cpa5, Mmus\Cpa1, Mmus\Cpb2, Mmus\Cpa6, Mmus\Cpb1, Mmus\Cpa3, Mmus\Cpa2" "Hsap\CPA6, Hsap\CPA4, Hsap\CPA5, Hsap\CPB1, Hsap\CPA2, Hsap\CPO, Hsap\CPA3, Hsap\CPA1, Hsap\CPB2" viable FBgn0011596 fzo fuzzy onions http://flybase.org/reports/FBgn0011596 "FBgn0044369, FBgn0044370, FBgn0044371" protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR030381 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000049197 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity Nebenkern assembly ; GO:0007287 | traceable author statement mitochondrial fusion ; GO:0008053 | inferred from mutant phenotype Nebenkern assembly ; GO:0007287 | inferred from mutant phenotype sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype mitochondrion localization ; GO:0051646 | inferred from biological aspect of ancestor with PANTHER:PTN000825684 mitochondrial fusion ; GO:0008053 | traceable author statement spermatogenesis ; GO:0007283 | traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006884 integral component of membrane ; GO:0016021 | traceable author statement mitochondrial envelope ; GO:0005740 | inferred from direct assay intrinsic component of mitochondrial outer membrane ; GO:0031306 | inferred from biological aspect of ancestor with PANTHER:PTN000825684 "CG4568, anon-WO0125274.26, anon-WO0125274.25, anon-WO0125274.1, fzo, Fzo" "IPR006884:Fzo/mitofusin HR2 domain, IPR022812:Dynamin superfamily, IPR030381:Dynamin-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027091:Transmembrane GTPase Fzo/Fzo1" CG4568 11-Aug-17 DroID_v2017_08 "Drer\LOC108179028, Drer\mfn2, Drer\mfn1a, Drer\mfn1b" Scer\FZO1 Cele\fzo-1 "Xtro\mfn2, Xtro\mfn1" "Mmus\Mfn1, Mmus\Mfn2" "Hsap\MFN1, Hsap\MFN2" spermatogenesis && adult stage " Nebenkern

, spermatid

" "male sterile,recessive,viable,female fertile" "spermatid,Nebenkern,spermatid & mitochondrion,onion stage spermatid & mitochondrion,Nebenkern | germline clone,Nebenkern derivative" FBgn0263557 mir-4967 mir-4967 stem loop http://flybase.org/reports/FBgn0263557 miRNA_gene - - - "mir-4967, dme-mir-4967, CR43542" - CR43542 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263261 spa1 - http://flybase.org/reports/FBgn0263261 gene - gonad development ; GO:0008406 | inferred from mutant phenotype - spa1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "gonad,gonadal sheath proper primordium" FBgn0038709 CG15025 - http://flybase.org/reports/FBgn0038709 protein_coding_gene - - - CG15025 - CG15025 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030851 CG8326 - http://flybase.org/reports/FBgn0030851 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BEST:LD29336, CG8326" IPR026680:Coiled-coil domain-containing protein 137 CG8326 11-Aug-17 DroID_v2017_08 Drer\ccdc137 - Cele\Y41D4B.11 - Mmus\Ccdc137 Hsap\CCDC137 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0026302 anon-49Da anon-49Da http://flybase.org/reports/FBgn0026302 - gene - - - "cDNA3, anon-49Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283627 CR46300 - http://flybase.org/reports/FBgn0283627 pseudogene_attribute - - - "CR46300, BP1072, CG34023, CG31544" "IPR009003:Peptidase S1, PA clan, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CR46300 11-Aug-17 DroID_v2017_08 - "Scer\APM1, Scer\APM3, Scer\APM2" "Cele\egg-2, Cele\rme-2" - "Mmus\Ldlrad1, Mmus\LOC102637808" Hsap\LDLRAD1 FBgn0086550 MRE19 mRNA-like ncRNA in embryogenesis 19 http://flybase.org/reports/FBgn0086550 non_protein_coding_gene - - - "MRE19, LD03248" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000536 eas easily shocked http://flybase.org/reports/FBgn0000536 "FBgn0043963, FBgn0044449" protein_coding_gene ethanolamine kinase activity ; GO:0004305 | inferred from direct assay choline kinase activity ; GO:0004103 | traceable author statement ethanolamine kinase activity ; GO:0004305 | non-traceable author statement choline kinase activity ; GO:0004103 | non-traceable author statement associative learning ; GO:0008306 | traceable author statement mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype habituation ; GO:0046959 | traceable author statement mushroom body development ; GO:0016319 | traceable author statement asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype long-term memory ; GO:0007616 | traceable author statement mushroom body development ; GO:0016319 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with kcc response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype phosphatidylethanolamine metabolic process ; GO:0046337 | inferred from direct assay response to hypoxia ; GO:0001666 | inferred from direct assay brain development ; GO:0007420 | inferred from mutant phenotype phosphorylation ; GO:0016310 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000004123 "ala, CG3525, EtnK, RH11, PC80, EP770, eas, RE10142" IPR011009:Protein kinase-like domain CG3525 11-Aug-17 DroID_v2017_08 "Drer\etnk2, Drer\zgc:113516, Drer\etnk1" "Scer\CKI1, Scer\EKI1" "Cele\cka-1, Cele\cka-2, Cele\ckc-1, Cele\ckb-1" - "Mmus\Etnk2, Mmus\Etnk1" "Hsap\CHKA, Hsap\ETNK2, Hsap\ETNK1" "viable,behavior defective,recessive,fertile,neuroanatomy defective,lethal,wild-type,memory defective,mitotic cell cycle defective,bang sensitive,paralytic,neurophysiology defective,chemical conditional,drug conditional" "mushroom body alpha-lobe,mushroom body beta-lobe,adult mushroom body beta'-lobe,adult mushroom body alpha'-lobe,calyx of adult mushroom body,adult heart,mushroom body & neuron | somatic clone,adult heart ventral longitudinal muscle" FBgn0038321 CG6218 - http://flybase.org/reports/FBgn0038321 protein_coding_gene N-acetylglucosamine kinase activity ; GO:0045127 | inferred from sequence or structural similarity with HGNC:17174 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:17174 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:17174 CG6218 "IPR002731:ATPase, BadF/BadG/BcrA/BcrD type" CG6218 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-84o3.3, Drer\LOC100000024, Drer\htra4, Drer\htra1a, Drer\htra3a, Drer\si:dkey-33c12.2, Drer\si:busm1-sl7.7, Drer\htra1b, Drer\htra3b, Drer\nagk, Drer\si:dkey-84o3.7" - "Cele\W06B4.2, Cele\C52A11.3, Cele\W06B4.1" "Xtro\htra4, Xtro\nagk, Xtro\htra1" "Mmus\Htra4, Mmus\Htra3, Mmus\Htra1, Mmus\Nagk, Mmus\Htra2" "Hsap\HTRA2, Hsap\HTRA4, Hsap\NAGK, Hsap\HTRA3, Hsap\HTRA1" "viable,fertile" DRSC15994 K -0.446154612 0.203588422 0.186444153 0.85682184 -1.100397164 1.719590348 FBgn0050365 spaw spacewatch http://flybase.org/reports/FBgn0050365 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG2149, BcDNA:AT04457, spaw, CG30365" - CG30365 11-Aug-17 DroID_v2017_08 Drer\matr3l1.2 - - - - - FBgn0036386 CG8833 - http://flybase.org/reports/FBgn0036386 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467 molecular_function ; GO:0003674 | no biological data available "mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR011666 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG8833, GPTC1" "IPR000467:G-patch domain, IPR011666:G patch domain-containing protein, N-terminal" CG8833 11-Aug-17 DroID_v2017_08 Drer\gpatch1 Scer\WHI2 Cele\R07E5.1 Xtro\gpatch1 Mmus\Gpatch1 Hsap\GPATCH1 "partially lethal - majority die,some die during pupal stage" "germline cell,male" FBgn0035294 Mfap1 Microfibril-associated protein 1 http://flybase.org/reports/FBgn0035294 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Prp38 "regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype" protein complex ; GO:0043234 | inferred from physical interaction with Prp38 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "dmfap1, Mfap1, CG1017" "IPR009730:Micro-fibrillar-associated protein 1, C-terminal" CG1017 11-Aug-17 DroID_v2017_08 Drer\mfap1 - Cele\mfap-1 Xtro\mfap1 "Mmus\Mfap1a, Mmus\Mfap1b" Hsap\MFAP1 "increased cell death,somatic clone,some die during larval stage,lethal - all die before end of larval stage,lethal,neuroanatomy defective" "wing disc,somatic clone,wing pouch,embryonic/larval neuroblast,ganglion mother cell" DRSC08154 I -0.341432633 1.621176125 -0.6308103 0.219067232 -0.832501431 -0.072645834 FBgn0021879 l(2)k13617 lethal (2) k13617 http://flybase.net/reports/FBgn0021879.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0050499 CG30499 - http://flybase.org/reports/FBgn0050499 protein_coding_gene ribulose-phosphate 3-epimerase activity ; GO:0004750 | inferred from electronic annotation with InterPro:IPR026019 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000056 pentose-phosphate shunt ; GO:0006098 | inferred from electronic annotation with InterPro:IPR026019 - "CG1364, CG30499" "IPR000056:Ribulose-phosphate 3-epimerase-like, IPR011060:Ribulose-phosphate binding barrel, IPR013785:Aldolase-type TIM barrel, IPR026019:Ribulose-phosphate 3-epimerase" CG30499 11-Aug-17 DroID_v2017_08 Drer\rpe Scer\RPE1 Cele\F08F8.7 Xtro\rpe Mmus\Rpe "Hsap\RPE, Hsap\RPEL1" "viable,fertile" FBgn0083983 mRpL34 mitochondrial ribosomal protein L34 http://flybase.org/reports/FBgn0083983 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000271 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000271 mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9BQ48 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CG34147, mRpL34" IPR000271:Ribosomal protein L34 CG34147 11-Aug-17 DroID_v2017_08 Drer\mrpl34 Scer\MRX14 - - Mmus\Mrpl34 Hsap\MRPL34 lethal FBgn0262381 mir-276b mir-276b stem loop http://flybase.org/reports/FBgn0262381 miRNA_gene - - - "dme-mir-276b, mir-276b, miR-276b, MIR-276, CR42904, Mir-276b, CR33586, MiR-276b, dme-miR-276b, miR-276, CR33587, dme-mir-276, mir-276bS" - CR42904 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,male limited" "wing,wing margin bristle,male limited" FBgn0052973 CG32973 - http://flybase.org/reports/FBgn0052973 protein_coding_gene - - - CG32973 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053244 Ste:CG33244 Ste:CG33244 http://flybase.org/reports/FBgn0053244 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG33244, CG32605, Ste:CG33244" "IPR016149:Casein kinase II, regulatory subunit, alpha-helical, IPR000704:Casein kinase II, regulatory subunit" CG33244 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0011557 107.1 107.1 http://flybase.org/reports/FBgn0011557 - gene - - - 107.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045051 fs(1)242 female sterile (1) 242 http://flybase.org/reports/FBgn0045051 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)242 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "ovary,dorsal appendage" FBgn0085789 CR41506 - http://flybase.org/reports/FBgn0085789 pseudogene_attribute - - - CR41506 - CR41506 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263938 BG00010 - http://flybase.org/reports/FBgn0263938 gene - - - BG00010 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,female limited,locomotor behavior defective" FBgn0266558 EP3639 - http://flybase.org/reports/FBgn0266558 gene - - - EP3639 - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval salivary gland FBgn0025501 l(3)73Am lethal (3) 73Am http://flybase.org/reports/FBgn0025501 - gene - - - l(3)73Am - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263003 CG43311 - http://flybase.org/reports/FBgn0263003 protein_coding_gene - - - CG43311 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053745 snmRNA:430:CR33745 snmRNA:430:CR33745 http://flybase.org/reports/FBgn0053745 non_protein_coding_gene - - - "CR33745, snmRNA:430:CR33745" - CR33745 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053410 5SrRNA:CR33410 5SrRNA:CR33410 http://flybase.org/reports/FBgn0053410 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33410, 5SrRNA:CR33410" - CR33410 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028242 l(3)S001405 lethal (3) S001405 http://flybase.org/reports/FBgn0028242 gene - - - "0014/05, l(3)S001405" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0014384 sev::tor sev::tor http://flybase.org/reports/FBgn0014384 - engineered_fusion_gene - - - sev::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "mystery cell,primary pigment cell,cone cell,eye,ommatidium,photoreceptor cell R7" FBgn0019786 l(1)17 lethal (1) 17 http://flybase.org/reports/FBgn0019786 - gene - - - l(1)17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032525 Hsp60D Heat shock protein 60D http://flybase.org/reports/FBgn0032525 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002423 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein refolding ; GO:0042026 | inferred from electronic annotation with InterPro:IPR001844 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:P10809 apoptotic process ; GO:0006915 | inferred from genetic interaction with hid inferred from genetic interaction with rpr inferred from genetic interaction with grim inferred from genetic interaction with Dronc 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 apoptotic mitochondrial changes ; GO:0008637 | inferred from biological aspect of ancestor with PANTHER:PTN000143510 protein import into mitochondrial intermembrane space ; GO:0045041 | inferred from biological aspect of ancestor with PANTHER:PTN000143508 'de novo' protein folding ; GO:0006458 | inferred from sequence or structural similarity with UniProtKB:P10809 chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000888029 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P10809 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000143507 "Hsp60D, CG16954, HSP60D" "IPR001844:Chaperonin Cpn60, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG16954 11-Aug-17 DroID_v2017_08 Drer\hspd1 "Scer\HSP60, Scer\TCM62" Cele\hsp-60 Xtro\hspd1 Mmus\Hspd1 Hsap\HSPD1 "lethal,partially,visible,increased cell death,viable" "eye,eye disc" FBgn0027276 l(1)G0200 lethal (1) G0200 http://flybase.org/reports/FBgn0027276 - gene - - - l(1)G0200 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036921 RhoGDI RhoGDI http://flybase.org/reports/FBgn0036921 protein_coding_gene Rho GDP-dissociation inhibitor activity ; GO:0005094 | inferred from electronic annotation with InterPro:IPR000406 - cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000406 "CG7823, RhoGDI" "IPR000406:Rho protein GDP-dissociation inhibitor, IPR014756:Immunoglobulin E-set, IPR024792:Rho GDP-dissociation inhibitor domain" CG7823 11-Aug-17 DroID_v2017_08 "Drer\arhgdig, Drer\arhgdia" Scer\RDI1 Cele\rhi-1 "Xtro\arhgdib, Xtro\arhgdia, Xtro\arhgdig" "Mmus\Arhgdib, Mmus\Arhgdig, Mmus\Arhgdia" "Hsap\ARHGDIA, Hsap\ARHGDIG, Hsap\ARHGDIB" "lethal,viable" FBgn0065499 l(2)SH1211 lethal (2) SH1211 http://flybase.org/reports/FBgn0065499 gene - - - "l(2)SH1211, l(2)SH2 1211" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264842 CR44050 - http://flybase.org/reports/FBgn0264842 non_protein_coding_gene - - - CR44050 - CR44050 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266378 CR45020 - http://flybase.org/reports/FBgn0266378 non_protein_coding_gene - - - CR45020 - CR45020 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011138 l(1)Q214 lethal (1) Q214 http://flybase.org/reports/FBgn0011138 FBgn0010210 gene - - - l(1)Q214 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034158 CG5522 - http://flybase.org/reports/FBgn0034158 protein_coding_gene Ral guanyl-nucleotide exchange factor activity ; GO:0008321 | inferred from sequence or structural similarity with HGNC:16851 regulation of Ral protein signal transduction ; GO:0032485 | inferred from sequence or structural similarity with HGNC:16851 cellular_component ; GO:0005575 | no biological data available "CG5522, RalGPS, RasGPS" "IPR001849:Pleckstrin homology domain, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR011993:PH domain-like, IPR023578:Ras guanine nucleotide exchange factor domain" CG5522 11-Aug-17 DroID_v2017_08 "Drer\ralgps2, Drer\LOC101882086, Drer\ralgps1" Scer\CDC25 Cele\sos-1 "Xtro\ralgps2, Xtro\ralgps1" "Mmus\Ralgps2, Mmus\Ralgps1" "Hsap\RALGPS2, Hsap\RALGPS1" "viable,fertile" FBgn0026389 Or43a Odorant receptor 43a http://flybase.org/reports/FBgn0026389 - protein_coding_gene "olfactory receptor activity ; GO:0004984 | inferred from direct assay olfactory receptor activity ; GO:0004984 | traceable author statement odorant binding ; GO:0005549 | traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | non-traceable author statement inferred by curator from GO:0004888,GO:0007608" protein heterooligomerization ; GO:0051291 | inferred from physical interaction with Orco sensory perception of smell ; GO:0007608 | inferred from expression pattern sensory perception of smell ; GO:0007608 | traceable author statement sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement dendrite membrane ; GO:0032590 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "Or43A, or43a, 43a, Or, DOR87, CG1854, AN14, 43B.1, Dor87, dor87, DOR43B.1, Or87, Or43B.1, 43B1, Or43a, OR43a, DOR43a" "IPR004117:Olfactory receptor, insect" CG1854 11-Aug-17 DroID_v2017_08 - - - - - - adult stage sensory neuron &&of antennal segment 3

"neurophysiology defective,viable" FBgn0052614 CG32614 - http://flybase.org/reports/FBgn0052614 protein_coding_gene - - - CG32614 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0265003 koi klaroid http://flybase.org/reports/FBgn0265003 protein_coding_gene - double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype nuclear envelope organization ; GO:0006998 | inferred from biological aspect of ancestor with PANTHER:PTN000308195 nuclear migration ; GO:0007097 | inferred from mutant phenotype nucleus localization ; GO:0051647 | inferred from mutant phenotype nuclear envelope ; GO:0005635 | inferred from biological aspect of ancestor with PANTHER:PTN000308195 nuclear periphery ; GO:0034399 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "koi, CG3287, CG44154, CG18584, BEST:LD11166, n(2)09967, Koi" "IPR008979:Galactose-binding domain-like, IPR012919:SUN domain" CG44154 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-92f12.2, Drer\zgc:152977, Drer\sun1" Scer\MPS3 "Cele\unc-84, Cele\sun-1" "Xtro\LOC100127596, Xtro\sun1" "Mmus\Sun1, Mmus\Sun3, Mmus\Spag4, Mmus\Sun5, Mmus\Sun2" "Hsap\GET4, Hsap\SUN5, Hsap\SUN1, Hsap\SUN2, Hsap\SPAG4, Hsap\SUN3" FBgn0036991 CG5872 - http://flybase.org/reports/FBgn0036991 protein_coding_gene - - - CG5872 - CG5872 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034769 Obp58c Odorant-binding protein 58c http://flybase.org/reports/FBgn0034769 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG13524, AAF46892, Obp58c, DmelObp58c" IPR006170:Pheromone/general odorant binding protein CG13524 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052408 CG32408 - http://flybase.org/reports/FBgn0052408 protein_coding_gene - - - CG32408 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029060 l(1)G0399 lethal (1) G0399 http://flybase.org/reports/FBgn0029060 gene - - - l(1)G0399 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0267871 CR46159 - http://flybase.org/reports/FBgn0267871 pseudogene_attribute - - - "CR46159, CG12717-related" - CR46159 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039233 CG7006 - http://flybase.org/reports/FBgn0039233 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002478 ribosome assembly ; GO:0042255 | inferred from electronic annotation with InterPro:IPR016686 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000602113 "nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000602113 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000602113" "BcDNA:GM12126, anon-WO0118547.410, CG7006, dNIP7" "IPR015947:PUA-like domain, IPR002478:PUA domain, IPR016686:Ribosome biogenesis factor, NIP7, IPR005155:Ribosome biogenesis factor NIP7-like" CG7006 11-Aug-17 DroID_v2017_08 Drer\nip7 Scer\NIP7 Cele\C43E11.9 Xtro\nip7 Mmus\Nip7 Hsap\NIP7 "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0051780 CG31780 - http://flybase.org/reports/FBgn0051780 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - CG31780 "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG31780 11-Aug-17 DroID_v2017_08 - - "Cele\try-1, Cele\try-3" - "Mmus\Klk1b11, Mmus\Klk1b22, Mmus\Klk1b26, Mmus\Klk1b24, Mmus\Klk1b21, Mmus\Klk1, Mmus\Klk1b1, Mmus\F9, Mmus\Klk11, Mmus\Klk1b27, Mmus\Klk1b5, Mmus\Klk1b9, Mmus\Klk1b3, Mmus\Klk1b8, Mmus\F11, Mmus\Klkb1, Mmus\Egfbp2, Mmus\Klk1b4, Mmus\Klk1b16" "Hsap\MASP1, Hsap\KLK1, Hsap\F11, Hsap\KLK11, Hsap\KLK2, Hsap\KLKB1, Hsap\KLK3" FBgn0259349 C207 - http://flybase.org/reports/FBgn0259349 gene - - - C207 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0002800 ms(1)16 male sterile (1) 16 http://flybase.org/reports/FBgn0002800 - gene - - - ms(1)16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile,viable" "spermatid,spermatid axoneme,Nebenkern derivative,spermatozoon" FBgn0027228 l(1)G0298 lethal (1) G0298 http://flybase.org/reports/FBgn0027228 - gene - - - l(1)G0298 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0035496 CG14990 - http://flybase.org/reports/FBgn0035496 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "SPH97, CG14990" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG14990 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Klk1b27, Mmus\Klk11, Mmus\Klk1b1, Mmus\F11, Mmus\Klkb1, Mmus\Egfbp2, Mmus\Klk1b9, Mmus\Klk1b8, Mmus\Klk1b21, Mmus\Klk1b24, Mmus\Klk1b4, Mmus\Klk1b22, Mmus\Klk1b11, Mmus\Klk1b5, Mmus\Klk1b26, Mmus\Klk1b16, Mmus\Klk1, Mmus\Klk1b3" "Hsap\KLK3, Hsap\KLK1, Hsap\KLKB1, Hsap\KLK2, Hsap\KLK11, Hsap\F11" "viable,fertile" FBgn0005720 l(1)TK128 lethal (1) TK128 http://flybase.org/reports/FBgn0005720 - gene - - - "l128, l(1)TK128" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0065047 snoRNA:U3:54Ab snoRNA:U3:54Ab http://flybase.org/reports/FBgn0065047 snoRNA_gene - - - "snoRNA U3, snoRNA:U3:54Ab, CR33628, Dm-818, U3 snoRNA, U3-snoRNA, 54A U3 snoRNA" - CR33628 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035264 Oseg4 Outer segment 4 http://flybase.org/reports/FBgn0035264 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000421275 cilium assembly ; GO:0060271 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype protein localization to cilium ; GO:0061512 | inferred from biological aspect of ancestor with PANTHER:PTN000421275 intraciliary retrograde transport ; GO:0035721 | inferred from biological aspect of ancestor with PANTHER:PTN000421277 non-motile cilium assembly ; GO:1905515 | inferred from sequence or structural similarity with Oseg1 intraciliary transport particle A ; GO:0030991 | inferred from biological aspect of ancestor with PANTHER:PTN000421277 intraciliary transport particle A ; GO:0030991 | inferred from sequence or structural similarity with HGNC:29250 non-motile cilium ; GO:0097730 | inferred from direct assay "OSEG4, cytC40, CG2069, Oseg4, OSEG, Wdr35, IFT121, oseg4, WDR35" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017233:WD repeat protein 35, IPR011990:Tetratricopeptide-like helical domain, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG2069 11-Aug-17 DroID_v2017_08 Drer\wdr35 - Cele\ifta-1 Xtro\wdr35 Mmus\Wdr35 Hsap\WDR35 "lethal,neuroanatomy defective,viable,partially lethal - majority die,recessive" ganglion mother cell FBgn0032039 CG13385 - http://flybase.org/reports/FBgn0032039 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13385 - CG13385 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033791 Drl-2 Derailed 2 http://flybase.org/reports/FBgn0033791 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with drl inferred from physical interaction with dnt protein tyrosine kinase activity ; GO:0004713 | NOT inferred from sequence or structural similarity with drl Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt5 "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266 chemorepulsion of axon ; GO:0061643 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | traceable author statement motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype" receptor complex ; GO:0043235 | inferred from direct assay "dnl, DNT-like, CG12463, CG3915, Drl-2, drl-2, DRL-2" "IPR000719:Protein kinase domain, IPR003306:WIF domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG3915 11-Aug-17 DroID_v2017_08 "Drer\mst1ra, Drer\mst1rb, Drer\met, Drer\ryk" Scer\KIN1 "Cele\lin-18, Cele\kin-9, Cele\F11E6.8, Cele\C24G6.2, Cele\scd-2" Xtro\ryk "Mmus\Mst1r, Mmus\Met, Mmus\Ryk" "Hsap\MET, Hsap\RYK, Hsap\MST1R" "viable,neuroanatomy defective" "presumptive embryonic salivary gland,antennal lobe,glomerulus,antennal lobe glomerulus VM7,antennal lobe glomerulus VL1" FBgn0001985 l(2)35De lethal (2) 35De http://flybase.org/reports/FBgn0001985 FBgn0001988 gene - - - "l(2)35Dh, l(2)br46, l35Dh, br46, l(2)35De" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,recessive" wing FBgn0261804 CG42750 - http://flybase.org/reports/FBgn0261804 protein_coding_gene metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR000180 dipeptidyl-peptidase activity ; GO:0008239 | inferred from electronic annotation with InterPro:IPR000180 dipeptidase activity ; GO:0016805 | inferred from biological aspect of ancestor with PANTHER:PTN000047764 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000180, InterPro:IPR008257" - "CG42750, CG15158, CG31786, CG42400, CG7198, CG7167, CG31746, CG15157" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR000180:Membrane dipeptidase, active site, IPR008257:Renal dipeptidase family, IPR032466:Metal-dependent hydrolase" CG42750 11-Aug-17 DroID_v2017_08 "Drer\cetn4, Drer\dpep1, Drer\dpep2, Drer\cetn3, Drer\cetn2" Scer\CDC31 Cele\math-31 "Xtro\cetn3, Xtro\cetn1, Xtro\dpep2, Xtro\cetn4, Xtro\dpep1" "Mmus\Cetn2, Mmus\Dpep3, Mmus\Cetn1, Mmus\Cetn4, Mmus\Dpep1, Mmus\Cetn3, Mmus\Dpep2" "Hsap\DPEP2, Hsap\DPEP3, Hsap\CETN3, Hsap\CETN2, Hsap\DPEP1, Hsap\CETN1" FBgn0040816 CG12521 - http://flybase.org/reports/FBgn0040816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12521 - CG12521 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004888 Scsalpha Succinyl coenzyme A synthetase alpha subunit http://flybase.org/reports/FBgn0004888 - protein_coding_gene cofactor binding ; GO:0048037 | inferred from electronic annotation with InterPro:IPR003781 succinate-CoA ligase (GDP-forming) activity ; GO:0004776 | inferred from sequence or structural similarity with UniProtKB:P53597 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P53597 neurogenesis ; GO:0022008 | inferred from mutant phenotype succinate-CoA ligase complex (GDP-forming) ; GO:0045244 | inferred from sequence or structural similarity with UniProtKB:P53597 mitochondrion ; GO:0005739 | inferred from direct assay "scsalpha, Scsalpha, CG1065, Scs-alpha" "IPR003781:CoA-binding, IPR005810:Succinyl-CoA ligase, alpha subunit, IPR005811:ATP-citrate lyase/succinyl-CoA ligase, IPR016040:NAD(P)-binding domain, IPR016102:Succinyl-CoA synthetase-like, IPR017440:ATP-citrate lyase/succinyl-CoA ligase, active site, IPR033847:ATP-citrate lyase/succinyl-CoA ligase, conserved site" CG1065 11-Aug-17 DroID_v2017_08 Drer\suclg1 Scer\LSC1 "Cele\sucl-1, Cele\sucl-2" Xtro\suclg1 Mmus\Suclg1 Hsap\SUCLG1 "viable,fertile,lethal,neuroanatomy defective,visible" "ganglion mother cell,trichogen cell" FBgn0037323 CG2663 - http://flybase.org/reports/FBgn0037323 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 CG2663 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG2663 11-Aug-17 DroID_v2017_08 "Drer\sec14l7, Drer\ttpa, Drer\rlbp1a, Drer\ttpal, Drer\clvs2, Drer\sec14l8, Drer\rlbp1b" "Scer\SFH5, Scer\SEC14, Scer\YKL091C" - "Xtro\rlbp1, Xtro\ttpa, Xtro\ttpal, Xtro\sec14l1, Xtro\mospd2, Xtro\clvs1, Xtro\sec14l3, Xtro\clvs2, Xtro\sec14l5" "Mmus\Sec14l2, Mmus\Clvs2, Mmus\Sec14l3, Mmus\Sec14l5, Mmus\Sec14l1, Mmus\Ttpal, Mmus\Ttpa, Mmus\Clvs1, Mmus\Sec14l4, Mmus\Rlbp1" "Hsap\SEC14L2, Hsap\SEC14L5, Hsap\CLVS1, Hsap\SEC14L3, Hsap\SEC14L1, Hsap\SEC14L4, Hsap\SEC14L6, Hsap\TTPA, Hsap\RLBP1, Hsap\TTPAL, Hsap\CLVS2" "viable,fertile" FBgn0060542 l(3)S099504 lethal (3) S099504 http://flybase.org/reports/FBgn0060542 gene - - - "0995/04, l(3)S099504" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0011182 l(1)294-16 lethal (1) 294-16 http://flybase.org/reports/FBgn0011182 FBgn0010200 gene - - - "294-16, l(1)294-16" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002159 l(2)pup lethal (2) pupal http://flybase.org/reports/FBgn0002159 - gene - - - l(2)pup - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "wing,leg" FBgn0037473 CG10068 - http://flybase.org/reports/FBgn0037473 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR030724 positive regulation of GTPase activity ; GO:0043547 | inferred from electronic annotation with InterPro:IPR030724 regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype - CG10068 "IPR006816:ELMO domain, IPR030724:ELMO domain-containing protein 2" CG10068 11-Aug-17 DroID_v2017_08 "Drer\elmod1, Drer\elmod3, Drer\elmod2" - Cele\C56G7.3 "Xtro\elmod2, Xtro\elmod1, Xtro\elmod3" "Mmus\Elmod3, Mmus\Elmod1, Mmus\Elmod2" "Hsap\ELMOD2, Hsap\ELMOD1, Hsap\ELMOD3" viable "wing hair,supernumerary" FBgn0265161 CR44230 - http://flybase.org/reports/FBgn0265161 non_protein_coding_gene - - - "CR44230, lincRNA.744" - CR44230 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264833 CR44041 - http://flybase.org/reports/FBgn0264833 non_protein_coding_gene - - - CR44041 - CR44041 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001025 fs(3)A16 female sterile (3) A16 http://flybase.org/reports/FBgn0001025 - gene - - - fs(3)A16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "ovary,oocyte" FBgn0262071 dlp::fz2 - http://flybase.org/reports/FBgn0262071 engineered_fusion_gene - - - dlp::fz2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034022 CG12964 - http://flybase.org/reports/FBgn0034022 protein_coding_gene - - - CG12964 - CG12964 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065758 l(2)SH0484 lethal (2) SH0484 http://flybase.org/reports/FBgn0065758 gene - - - "l(2)SH0484, l(2)SH2 0484" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0066309 BPP.s BPP.s http://flybase.org/reports/FBgn0066309 gene - - - "BPPs, BPP.s, BPP" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037602 SLIRP2 SRA stem-loop interacting RNA binding protein 2 http://flybase.org/reports/FBgn0037602 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 protein binding ; GO:0005515 | inferred from physical interaction with Lrpprc2 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity lateral inhibition ; GO:0046331 | inferred from mutant phenotype exon-exon junction complex ; GO:0035145 | colocalizes_with inferred from direct assay "cg8021, CG8021, SLIRP2, DmSLIRP2" "IPR000504:RNA recognition motif domain, IPR034152:SLIRP, RNA recognition motif" CG8021 11-Aug-17 DroID_v2017_08 "Drer\raly, Drer\rbm34, Drer\zgc:55733, Drer\cirbpa, Drer\slirp, Drer\eif4ba, Drer\eif4h, Drer\trnau1apb, Drer\zgc:110796, Drer\hnrnpa3, Drer\ncoa5, Drer\dazl, Drer\wu:fq32h04, Drer\hnrnpd, Drer\hnrnpc, Drer\hnrnpaba, Drer\hnrnpabb, Drer\trnau1apa, Drer\hnrnpa1b, Drer\zcrb1, Drer\srsf10a" "Scer\MRN1, Scer\MUD1, Scer\NGR1, Scer\CWC2, Scer\NAB6, Scer\NOP12, Scer\NAM8, Scer\NOP15, Scer\NOP6" "Cele\R09B3.3, Cele\R09B3.2, Cele\R06C1.4, Cele\C50B8.1" "Xtro\hnrnpa3, Xtro\cirbp, Xtro\eif4b, Xtro\hnrnpc, Xtro\raly, Xtro\eif4h, Xtro\hnrnpa1, Xtro\dazl, Xtro\trnau1ap, Xtro\hnrnpd, Xtro\ralyl, Xtro\hnrnpdl, Xtro\hnrnpab, Xtro\hnrnpa2b1, Xtro\rbm34" "Mmus\Hnrnpa2b1, Mmus\Hnrnpa3, Mmus\Hnrnpab, Mmus\Cirbp, Mmus\Tra2b, Mmus\Dazl, Mmus\Msi2, Mmus\Hnrnpd, Mmus\Eif4h, Mmus\Eif4b, Mmus\Boll, Mmus\Srsf10, Mmus\Hnrnpc, Mmus\Zcrb1, Mmus\Trnau1ap, Mmus\Hnrnpa1, Mmus\Gm21379, Mmus\Srsf12, Mmus\Rbm34, Mmus\Rbm31y, Mmus\Raly, Mmus\Slirp" "Hsap\HNRNPA1L2, Hsap\CIRBP, Hsap\DAZ3, Hsap\HNRNPA2B1, Hsap\RBM3, Hsap\RALY, Hsap\EIF4H, Hsap\DAZ4, Hsap\EIF4B, Hsap\TRNAU1AP, Hsap\SLIRP, Hsap\DAZL, Hsap\BOLL, Hsap\HNRNPA3, Hsap\HNRNPA1, Hsap\HNRNPAB, Hsap\RALYL, Hsap\SRSF10, Hsap\DAZ2, Hsap\HNRNPC, Hsap\HNRNPCL1, Hsap\DAZ1, Hsap\RBM34, Hsap\HNRNPD" "viable,visible" "chaeta,supernumerary,trichogen cell,wing" FBgn0022978 rrpC reduced receptor potential C http://flybase.org/reports/FBgn0022978 - gene - - - rrpC - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259896 NimC1 Nimrod C1 http://flybase.org/reports/FBgn0259896 protein_coding_gene molecular_function ; GO:0003674 | no biological data available phagocytosis ; GO:0006909 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay "CG8942, P1, CT25688, BG:DS00180.10, nimrod, NimC1, NimC, Nim, nimC1" "IPR009030:Growth factor receptor cysteine-rich domain, IPR011489:EMI domain, IPR013032:EGF-like, conserved site, IPR000742:EGF-like domain" CG8942 11-Aug-17 DroID_v2017_08 "Drer\angptl4, Drer\megf6b, Drer\si:ch1073-110a20.2, Drer\si:zfos-2330d3.8, Drer\pear1, Drer\zgc:194887, Drer\tnr, Drer\tnfrsf1b, Drer\si:ch1073-110a20.1, Drer\esm1, Drer\angptl6, Drer\angptl5, Drer\LOC100007488, Drer\si:ch211-287a12.9, Drer\scarf1, Drer\angptl1a, Drer\wu:fj11g02, Drer\megf10, Drer\angptl2a, Drer\tnc, Drer\tnw, Drer\si:zfos-2330d3.3, Drer\si:ch1073-110a20.3, Drer\tnfrsf21, Drer\si:ch211-203k16.3, Drer\angpt1, Drer\dll4, Drer\angpt2b, Drer\si:zfos-2330d3.6, Drer\fgl2b, Drer\fgg, Drer\ccbe1, Drer\fgl2a, Drer\si:zfos-2330d3.1, Drer\tnxba, Drer\angptl3, Drer\fgb, Drer\fibcd1, Drer\tnfaip6, Drer\dkk1a, Drer\megf11, Drer\angpt4, Drer\megf6a, Drer\zgc:171687, Drer\angptl2b, Drer\zgc:158328, Drer\zmp:0000000846, Drer\fga, Drer\dkk2, Drer\si:ch211-157b11.8" - "Cele\Y34B4A.5, Cele\Y69H2.3, Cele\pqn-13, Cele\C08G9.2, Cele\abu-15, Cele\W05B2.2, Cele\F35A5.4, Cele\R09H10.5, Cele\pqn-91, Cele\B0393.5, Cele\ensh-1, Cele\Y26D4A.12, Cele\ZK1193.3, Cele\Y69H2.10, Cele\abu-6, Cele\Y43C5A.2, Cele\T15B7.1, Cele\ZC504.1, Cele\pqn-90, Cele\K10D3.4, Cele\F07H5.8" "Xtro\angpt4, Xtro\angptl3, Xtro\fgb, Xtro\fibcd1, Xtro\tnxb, Xtro\angpt1, Xtro\tnc, Xtro\angptl5, Xtro\tnr, Xtro\fbln1, Xtro\mfap4, Xtro\LOC100497330, Xtro\fcn1, Xtro\angptl4, Xtro\fcn2, Xtro\tnfaip6, Xtro\LOC100491105, Xtro\stab2, Xtro\angptl2, Xtro\fgl1, Xtro\fgg, Xtro\fga, Xtro\LOC100488177, Xtro\fcn3, Xtro\tnn, Xtro\fgl2, Xtro\megf11" "Mmus\Tnr, Mmus\Fcnb, Mmus\Fga, Mmus\Dkk3, Mmus\Angptl2, Mmus\Egfem1, Mmus\Pear1, Mmus\Tnfrsf21, Mmus\Stab1, Mmus\Fgg, Mmus\Tnxb, Mmus\Tnfrsf1b, Mmus\Fgb, Mmus\Angptl6, Mmus\Fcna, Mmus\Megf6, Mmus\Fgl1, Mmus\Dner, Mmus\Angpt1, Mmus\Dkk2, Mmus\Fibcd1, Mmus\Scarf1, Mmus\Angptl3, Mmus\Angptl4, Mmus\Angptl1, Mmus\Tnfaip6, Mmus\Tnn, Mmus\Tnfrsf11b, Mmus\Megf11, Mmus\Angpt4, Mmus\Angptl7, Mmus\Angpt2, Mmus\Fgl2, Mmus\Megf10, Mmus\Mfap4, Mmus\Tnc, Mmus\Esm1" "Hsap\SCARF2, Hsap\ANGPTL4, Hsap\ANGPT2, Hsap\FGG, Hsap\MEGF10, Hsap\FGL1, Hsap\FIBCD1, Hsap\TNN, Hsap\MEGF6, Hsap\ANGPT4, Hsap\FGL2, Hsap\PEAR1, Hsap\TNFRSF11B, Hsap\ANGPTL1, Hsap\ANGPTL7, Hsap\FCN2, Hsap\TNFRSF21, Hsap\ANGPTL2, Hsap\TNXB, Hsap\ANGPTL3, Hsap\FCN3, Hsap\FGB, Hsap\TNR, Hsap\MEGF11, Hsap\ANGPT1, Hsap\ANGPTL6, Hsap\ANGPTL5, Hsap\SCARF1, Hsap\DKK2, Hsap\TNC, Hsap\FGA, Hsap\TNFRSF1B, Hsap\TNFAIP6" FBgn0267646 CR45984 - http://flybase.org/reports/FBgn0267646 non_protein_coding_gene - - - CR45984 - CR45984 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000675 flp flipper http://flybase.org/reports/FBgn0000675 - gene - - - flp - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,sterile,body color defective,fertile" "wing,adult cuticle" FBgn0259288 EP-472 - http://flybase.org/reports/FBgn0259288 gene - - - EP-472 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta" FBgn0000401 cx curlex http://flybase.org/reports/FBgn0000401 - gene - - - cx - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced,male sterile,recessive" "wing,genitalia" FBgn0035334 CG8993 - http://flybase.org/reports/FBgn0035334 protein_coding_gene protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR005746 disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence or structural similarity with UniProtKB:Q99757 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR005746, InterPro:IPR013766 glycerol ether metabolic process ; GO:0006662 | inferred from electronic annotation with InterPro:IPR005746 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q99757 "CG8993, 8993" "IPR005746:Thioredoxin, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain" CG8993 11-Aug-17 DroID_v2017_08 "Drer\txn, Drer\txn2, Drer\zgc:56493" "Scer\TRX2, Scer\TRX1, Scer\TRX3" "Cele\trx-1, Cele\trx-2, Cele\trx-4, Cele\Y55F3AR.2" Xtro\txn2 "Mmus\Txn1, Mmus\Txn2" "Hsap\TXN2, Hsap\TXN" "viable,visible" trichogen cell FBgn0260328 GSd056 - http://flybase.org/reports/FBgn0260328 gene - - - GSd056 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032973 CG6675 - http://flybase.org/reports/FBgn0032973 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available CG6675 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6675 11-Aug-17 DroID_v2017_08 "Drer\lpl, Drer\LOC101884800, Drer\LOC100331214, Drer\lipg, Drer\pla1a, Drer\lipca" - - "Xtro\lpl, Xtro\LOC100486161, Xtro\lipg" "Mmus\Pla1a, Mmus\Lpl, Mmus\Lipc, Mmus\Lipg, Mmus\Pnliprp2, Mmus\Pnlip" "Hsap\LPL, Hsap\PLA1A, Hsap\LIPC, Hsap\PNLIPRP1, Hsap\PNLIP, Hsap\PNLIPRP2, Hsap\LIPG" viable FBgn0032782 Rab9 Rab9 http://flybase.org/reports/FBgn0032782 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity protein complex binding ; GO:0032403 | inferred from physical interaction with Vps35 protein binding ; GO:0005515 | inferred from physical interaction with GM130" "retrograde transport, endosome to Golgi ; GO:0042147 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 retrograde transport, endosome to Golgi ; GO:0042147 | traceable author statement" late endosome ; GO:0005770 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 synapse ; GO:0045202 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay "146494_at, DmRab9, CG9994, Rab9, rab9" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9994 11-Aug-17 DroID_v2017_08 "Drer\rab7, Drer\rab9b, Drer\rab9a, Drer\si:dkey-13a21.4, Drer\zgc:91909" Scer\YPT7 "Cele\rab-7, Cele\C52B11.5" "Xtro\MGC75872, Xtro\rab9a, Xtro\rab7b, Xtro\rab9b, Xtro\rab7a" "Mmus\Rab9, Mmus\Rab9b, Mmus\Rab7, Mmus\Rab7b" "Hsap\RAB9A, Hsap\RAB7A, Hsap\RAB9B" viable "embryonic/larval dorsal trunk,mesothoracic tergum" FBgn0065235 l(2)SH2166 lethal (2) SH2166 http://flybase.org/reports/FBgn0065235 gene - - - "l(2)SH2166, l(2)SH2 2166" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053117 Victoria Victoria http://flybase.org/reports/FBgn0053117 protein_coding_gene - cellular response to UV ; GO:0034644 | inferred from expression pattern response to heat ; GO:0009408 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern cellular response to heat ; GO:0034605 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with TotA "TotE, CG13963, CG33117, Victoria" IPR010825:Stress-inducible humoral factor Turandot CG33117 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259949 Sfp23F Seminal fluid protein 23F http://flybase.org/reports/FBgn0259949 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "Sfp23F, CG42459" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42459 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259469 C632 - http://flybase.org/reports/FBgn0259469 gene - - - C632 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0036969 Spn77Bb Serpin 77Bb http://flybase.org/reports/FBgn0036969 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG6266, Spn77Bb, CG6663, Spn77" "IPR000215:Serpin family, IPR023796:Serpin domain" CG6663 11-Aug-17 DroID_v2017_08 "Drer\serpind1, Drer\serpini1, Drer\serpinf1, Drer\serping1, Drer\serpinf2b, Drer\agt, Drer\serpinf2a" - "Cele\srp-6, Cele\srp-7, Cele\srp-2, Cele\srp-1, Cele\srp-8, Cele\C28G1.2, Cele\srp-3" "Xtro\serpine1, Xtro\serpinf2" "Mmus\Serpinb7, Mmus\Serpini1, Mmus\Serpini2, Mmus\Serpinf1, Mmus\Serpind1, Mmus\Serpinf2, Mmus\Agt" "Hsap\SERPINB7, Hsap\SERPIND1, Hsap\SERPINF2, Hsap\SERPINI2, Hsap\AGT, Hsap\SERPINI1, Hsap\SERPINF1" "lethal,body color defective" mesothoracic tergum FBgn0069328 X-136-10 X-136-10 http://flybase.org/reports/FBgn0069328 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-136-10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,cephalopharyngeal skeleton" FBgn0033686 Hen1 Hen1 methyltransferase http://flybase.org/reports/FBgn0033686 protein_coding_gene RNA methyltransferase activity ; GO:0008173 | inferred from electronic annotation with InterPro:IPR026610 O-methyltransferase activity ; GO:0008171 | inferred from direct assay piRNA metabolic process ; GO:0034587 | inferred from direct assay posttranscriptional gene silencing by RNA ; GO:0035194 | inferred from mutant phenotype RNA methylation ; GO:0001510 | inferred from direct assay RNA methylation ; GO:0001510 | inferred from direct assay inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from direct assay - "DmHen1, CG12367, hen1, PIMET, Pimet, Hen1, FBgn 33686, hen-1, Pimet/DmHen1" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR026610:3'-RNA ribose 2'-O-methyltransferase, Hen1" CG12367 11-Aug-17 DroID_v2017_08 Drer\henmt1 - Cele\henn-1 Xtro\henmt1 Mmus\Henmt1 Hsap\HENMT1 "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0014992 l(2)47Aa lethal (2) 47Aa http://flybase.org/reports/FBgn0014992 - gene - - - l(2)47Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010323 Gsc Goosecoid http://flybase.org/reports/FBgn0010323 "FBgn0004887, FBgn0008637, FBgn0010598" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Gsc transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with oc" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement" nucleus ; GO:0005634 | inferred by curator from GO:0001078 "gsc, D-gsc, D-Gsc, Pph25, 60Mun2, l(2)05341, 60Mun1, PPH25, M72, CG2851, Gsc, GSC" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG2851 11-Aug-17 DroID_v2017_08 "Drer\dharma, Drer\dmbx1b, Drer\pdlim7, Drer\hoxb8a, Drer\lhx6, Drer\ldb3a, Drer\pitx3, Drer\pax6b, Drer\mxtx2, Drer\pitx1, Drer\gsc, Drer\shox, Drer\pdlim3b, Drer\pax6a, Drer\dmbx1a, Drer\shox2" "Scer\PHO2, Scer\YHP1, Scer\PXL1" "Cele\ttx-1, Cele\ceh-45, Cele\vab-3, Cele\ceh-51, Cele\lim-4, Cele\alp-1" "Xtro\pitx1, Xtro\hoxb8, Xtro\pitx3, Xtro\pdlim5, Xtro\shox2, Xtro\lhx8, Xtro\gsc" "Mmus\Lhx6, Mmus\Gsc2, Mmus\Lhx8, Mmus\Ldb3, Mmus\Dmbx1, Mmus\Pdlim7, Mmus\Pdlim1, Mmus\Pitx3, Mmus\Pdlim3, Mmus\Pax6, Mmus\Gsc, Mmus\Shox2, Mmus\Pdlim5, Mmus\Pitx1" "Hsap\SHOX, Hsap\LHX6, Hsap\LPXN, Hsap\DMBX1, Hsap\LHX8, Hsap\PITX1, Hsap\PAX6, Hsap\GSC, Hsap\LDB3, Hsap\PITX3, Hsap\HOXB8, Hsap\SHOX2, Hsap\PDLIM7, Hsap\PDLIM1, Hsap\PDLIM3, Hsap\GSC2" " embryonic stage | blastoderm , embryonic stage | stage 16 , embryonic stage | stage >=11 , embryonic stage , embryonic stage | stage >=10 " " procephalic neurogenic region

, embryonic stomatogastric nervous system

, stomodeum

, ring gland

, embryonic/larval foregut

, embryonic brain | restricted

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "stomatogastric nervous system,embryonic/larval foregut" FBgn0039744 CG15526 - http://flybase.org/reports/FBgn0039744 protein_coding_gene ribonuclease activity ; GO:0004540 | inferred from electronic annotation with InterPro:IPR002759 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR002759 - CG15526 IPR002759:Ribonuclease P/MRP protein subunit CG15526 11-Aug-17 DroID_v2017_08 Drer\rpp14 - - Xtro\rpp14 Mmus\Rpp14 Hsap\RPP14 viable DRSC15063 K -0.036205649 0.11048549 -1.163494847 0.450279742 -1.669813626 -0.947216445 FBgn0265552 l(3)KG06256 - http://flybase.org/reports/FBgn0265552 gene - - - l(3)KG06256 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083228 Frq2 Frequenin 2 http://flybase.org/reports/FBgn0083228 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" neurotransmitter secretion ; GO:0007269 | non-traceable author statement regulation of neurotransmitter secretion ; GO:0046928 | inferred from genetic interaction with Frq1 vesicle-mediated transport ; GO:0016192 | non-traceable author statement chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype synaptic vesicle ; GO:0008021 | non-traceable author statement "CG5907, frq2, Frq, Frq2, frq" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG5907 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-245j22.3, Drer\rcvrn2, Drer\kcnip2, Drer\kcnip3b, Drer\kcnip1b, Drer\hpca, Drer\guca1d, Drer\ncs1b, Drer\efcab1, Drer\guca1e, Drer\kcnip4, Drer\hpcal4, Drer\guca1g, Drer\rcvrnb, Drer\usp32, Drer\kcnip1a, Drer\vsnl1b, Drer\guca1c, Drer\guca1a, Drer\ncalda, Drer\ncaldb, Drer\si:ch211-145b13.5, Drer\rcvrn3, Drer\si:ch211-103a14.5, Drer\vsnl1a, Drer\rcvrna, Drer\hpcal1, Drer\guca1b, Drer\ncs1a" Scer\FRQ1 "Cele\ncs-1, Cele\ncs-2, Cele\ncs-3" "Xtro\kcnip3, Xtro\hpca, Xtro\efcab1, Xtro\guca1b, Xtro\ncs1, Xtro\ncald, Xtro\guca1c, Xtro\hpcal1, Xtro\kcnip2, Xtro\rcvrn.2, Xtro\kcnip4, Xtro\kcnip1, Xtro\guca1a, Xtro\vsnl1" "Mmus\Kcnip4, Mmus\Hpcal4, Mmus\Kcnip1, Mmus\Usp32, Mmus\1700109H08Rik, Mmus\Kcnip3, Mmus\Guca1a, Mmus\Vsnl1, Mmus\Hpcal1, Mmus\Rcvrn, Mmus\Guca1b, Mmus\Ncs1, Mmus\Hpca, Mmus\Efcab1, Mmus\Kcnip2, Mmus\Ncald" "Hsap\EFCAB1, Hsap\KCNIP3, Hsap\NCALD, Hsap\KCNIP4, Hsap\GUCA1A, Hsap\GUCA1C, Hsap\GUCA1B, Hsap\KCNIP2, Hsap\HPCA, Hsap\HPCAL4, Hsap\HPCAL1, Hsap\VSNL1, Hsap\RCVRN, Hsap\USP32, Hsap\NCS1, Hsap\KCNIP1" "viable,fertile,neuroanatomy defective,neurophysiology defective,locomotor behavior defective" "type I bouton,embryonic/larval neuromuscular junction,NMJ bouton" FBgn0038204 CG14357 - http://flybase.org/reports/FBgn0038204 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14357 - CG14357 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065323 l(2)SH1912 lethal (2) SH1912 http://flybase.org/reports/FBgn0065323 gene - - - "l(2)SH1912, l(2)SH2 1912" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266871 CR45332 - http://flybase.org/reports/FBgn0266871 non_protein_coding_gene - - - CR45332 - CR45332 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263500 CR43489 - http://flybase.org/reports/FBgn0263500 non_protein_coding_gene - - - "CR43489, lincRNA.801" - CR43489 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069403 KH2 KH2 http://flybase.org/reports/FBgn0069403 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available KH2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062623 Mod(var)1128 Mod(var)1128 http://flybase.org/reports/FBgn0062623 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1128, Mod(var)1128" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0030839 CG5613 - http://flybase.org/reports/FBgn0030839 protein_coding_gene mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity ; GO:0033925 | inferred from electronic annotation with InterPro:IPR005201 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A - lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000326692 CG5613 "IPR005201:Glycoside hydrolase, family 85, IPR008979:Galactose-binding domain-like, IPR032979:Cytosolic endo-beta-N-acetylglucosaminidase" CG5613 11-Aug-17 DroID_v2017_08 Drer\engase - Cele\eng-1 Xtro\engase Mmus\Engase Hsap\ENGASE "viable,fertile" FBgn0260462 CG12163 - http://flybase.org/reports/FBgn0260462 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx inferred from genetic interaction with ap proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 autophagic cell death ; GO:0048102 | inferred from expression pattern chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 perivitelline space ; GO:0098595 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 "anon-WO0118547.305, CG12163" "IPR000169:Cysteine peptidase, cysteine active site, IPR000668:Peptidase C1A, papain C-terminal, IPR013128:Peptidase C1A, IPR013201:Cathepsin propeptide inhibitor domain (I29), IPR025661:Cysteine peptidase, asparagine active site, IPR025660:Cysteine peptidase, histidine active site" CG12163 11-Aug-17 DroID_v2017_08 "Drer\ctsl.1, Drer\ctsf, Drer\ctso, Drer\ctss2.1, Drer\ctsla, Drer\ctss2.2" - "Cele\K02E7.10, Cele\R09F10.1, Cele\tag-196, Cele\R07E3.1, Cele\Y71H2AM.25, Cele\C32B5.13, Cele\Y71H2AR.2, Cele\cpl-1, Cele\C32B5.7" "Xtro\ctsf, Xtro\ctsw" "Mmus\Ctsw, Mmus\Ctss, Mmus\Ctsl, Mmus\Ctsf, Mmus\Ctso, Mmus\BC051665, Mmus\Ctsll3" "Hsap\CTSO, Hsap\CTSF, Hsap\CTSK, Hsap\CTSL, Hsap\CTSS, Hsap\CTSW, Hsap\CTSV" viable FBgn0021585 DdbP2 Damage-specific DNA-binding protein 2 http://flybase.org/reports/FBgn0021585 - gene damaged DNA binding ; GO:0003684 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "D-DDB P2, DdbP2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259526 B0511 - http://flybase.org/reports/FBgn0259526 gene - - - B0511 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0023051 l(1)3Al lethal (1) 3Al http://flybase.org/reports/FBgn0023051 - gene - - - "C2/5.6, l(1)3Al" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037442 godzilla godzilla E3 ubiquitin protein ligase http://flybase.org/reports/FBgn0037442 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model protein ubiquitination ; GO:0016567 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from direct assay "CG10277, godzilla, godzilla[CG10277]" "IPR001841:Zinc finger, RING-type, IPR003137:PA domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10277 11-Aug-17 DroID_v2017_08 "Drer\rnf128a, Drer\LOC100536511, Drer\rnf167, Drer\rnf181, Drer\rnf13" - "Cele\plr-1, Cele\C18B12.4" "Xtro\rnf13, Xtro\rnf167, Xtro\rnf181" "Mmus\Rnf133, Mmus\Rnf167, Mmus\Rnf128, Mmus\Rnf181, Mmus\Rnf148, Mmus\Znrf4, Mmus\Rnf13" "Hsap\RNF128, Hsap\RNF167, Hsap\RNF133, Hsap\RNF181, Hsap\RNF148, Hsap\RNF13, Hsap\ZNRF4" viable "endosomeBx-MS1096,rhabdomere R7,endosomegodzilla‘î1)" FBgn0039203 CG13618 - http://flybase.org/reports/FBgn0039203 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG13618 IPR010562:Haemolymph juvenile hormone binding CG13618 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0086375 EP3377 - http://flybase.org/reports/FBgn0086375 gene - - - EP3377 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051126 CG31126 - http://flybase.org/reports/FBgn0051126 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG13621, CG31126" IPR002634:BolA protein CG31126 11-Aug-17 DroID_v2017_08 "Drer\zgc:112271, Drer\bola1, Drer\bola3" "Scer\FRA2, Scer\AIM1, Scer\YAL044W-A" "Cele\Y105E8A.11, Cele\T12D8.10, Cele\K11H12.1" "Xtro\bola1, Xtro\bola2" "Mmus\Bola1, Mmus\Bola2, Mmus\Bola3" "Hsap\BOLA1, Hsap\BOLA3, Hsap\LOC107984053" viable FBgn0264391 CR43839 - http://flybase.org/reports/FBgn0264391 non_protein_coding_gene - - - CR43839 - CR43839 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267259 CR45695 - http://flybase.org/reports/FBgn0267259 non_protein_coding_gene - - - CR45695 - CR45695 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031776 Pfdn1 Prefoldin 1 http://flybase.org/reports/FBgn0031776 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR002777 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002777 prefoldin complex ; GO:0016272 | colocalizes_with inferred from direct assay "anon-EST:Posey288, CG13993, Pfdn1, pfdn1" IPR002777:Prefoldin beta-like CG13993 11-Aug-17 DroID_v2017_08 Drer\pfdn1 Scer\PFD1 Cele\pfd-1 Xtro\pfdn1 Mmus\Pfdn1 Hsap\PFDN1 viable embryonic/larval salivary gland FBgn0267653 CR45991 - http://flybase.org/reports/FBgn0267653 non_protein_coding_gene - - - CR45991 - CR45991 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034572 CG9346 - http://flybase.org/reports/FBgn0034572 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR000061 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR000061 biological_process ; GO:0008150 | no biological data available nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:30855 "cg9346, CG9346" "IPR000061:SWAP/Surp, IPR000504:RNA recognition motif domain, IPR006569:CID domain, IPR013170:mRNA splicing factor Cwf21 domain, IPR008942:ENTH/VHS" CG9346 11-Aug-17 DroID_v2017_08 "Drer\u2surp, Drer\zgc:163098" - Cele\C07H6.4 Xtro\u2surp Mmus\U2surp Hsap\U2SURP viable FBgn0028946 Or35a Odorant receptor 35a http://flybase.org/reports/FBgn0028946 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "CG17868, 35a, DOR91, 36E.1, BACR44L22.5, BG:BACR44L22.5, Or35a, OR35a" "IPR004117:Olfactory receptor, insect" CG17868 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,chemosensitive behavior defective,smell perception defective" olfactory sensory organ FBgn0001436 l(1)7Bd lethal (1) 7Bd http://flybase.org/reports/FBgn0001436 - gene - - - "l(1)VA156, l(1)RC21, l(1)N63, l(1)7Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262750 Mst77Y-1 Male-specific transcript 77Y 1 http://flybase.org/reports/FBgn0262750 nuclear_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F Mst77Y-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040519 CG15219 - http://flybase.org/reports/FBgn0040519 protein_coding_gene - - - "BcDNA:LP09525, CG15219, cg15219" - CG15219 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC03715 I -1.502898229 0.098089064 -0.321104769 0.773287686 0.230297516 -1.362630671 FBgn0019783 l(1)22 lethal (1) 22 http://flybase.org/reports/FBgn0019783 - gene - - - l(1)22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022285 l(2)IR10 lethal (2) IR10 http://flybase.org/reports/FBgn0022285 - gene - - - l(2)IR10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027590 GstE12 Glutathione S transferase E12 http://flybase.org/reports/FBgn0027590 - protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "BcDNA:GH04753, CG16936, GST, GstE12, gste12, GSTE12" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG16936 11-Aug-17 DroID_v2017_08 "Drer\gstt2, Drer\vars, Drer\gstt1a, Drer\eef1g, Drer\gstt1b, Drer\eef1e1, Drer\mars, Drer\gstr" "Scer\YGR201C, Scer\TEF4, Scer\CAM1, Scer\GTT2, Scer\URE2, Scer\GTT1" Cele\gst-34 "Xtro\eef1g, Xtro\gstt1, Xtro\eef1e1" "Mmus\Gstt3, Mmus\Mars, Mmus\Gstt4, Mmus\Gstt2, Mmus\Vars, Mmus\Eef1e1, Mmus\Eef1g, Mmus\Gstt1" "Hsap\EEF1E1, Hsap\GSTT1, Hsap\GSTT2B, Hsap\VARS, Hsap\MARS, Hsap\GSTT2, Hsap\EEF1G" viable FBgn0260053 2L2416 - http://flybase.org/reports/FBgn0260053 gene - - - 2L2416 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0024626 l(2)k16616 lethal (2) k16616 http://flybase.org/reports/FBgn0024626 - gene - - - "166/16, l(2)k16616" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0043022 snRNA:U5:38ABa snRNA:U5:38ABa http://flybase.org/reports/FBgn0043022 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-38ABa, K2, dU5, CR32881, U5snRNA, snRNA:U5, snRNA:U5:38ABa, U5var:38ABa, U5:38ABa, U5 snRNA, U5 38ABa, 38A U5" - CR32881 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031022 CG12204 - http://flybase.org/reports/FBgn0031022 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12204 IPR015943:WD40/YVTN repeat-like-containing domain CG12204 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0024759 EC70 EC70 http://flybase.org/reports/FBgn0024759 - gene - - - EC70 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,non-enhancer of variegation" FBgn0003694 thb thin bristle http://flybase.org/reports/FBgn0003694 - gene - - - thb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,female,reduced,female fertile" "macrochaeta,vibrissae,eye,wing vein L5,posterior crossvein" FBgn0029664 CG10802 - http://flybase.org/reports/FBgn0029664 protein_coding_gene "alanine-tRNA ligase activity ; GO:0004813 | inferred from electronic annotation with InterPro:IPR018164, InterPro:IPR018165 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012947, InterPro:IPR018164, InterPro:IPR018165 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR018165" "alanyl-tRNA aminoacylation ; GO:0006419 | inferred from electronic annotation with InterPro:IPR018164, InterPro:IPR018165" - "anon-EST:Posey113, CG10802" "IPR012947:Threonyl/alanyl tRNA synthetase, SAD, IPR009000:Translation protein, beta-barrel domain, IPR018163:Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR018165:Alanyl-tRNA synthetase, class IIc, core domain, IPR018164:Alanyl-tRNA synthetase, class IIc, N-terminal" CG10802 11-Aug-17 DroID_v2017_08 Drer\aarsd1 Scer\YNL040W - Xtro\aarsd1 "Mmus\Ptges3l, Mmus\Aarsd1" Hsap\AARSD1 "viable,visible" mesothoracic tergum FBgn0041596 l(2)PJ25 lethal (2) PJ25 http://flybase.org/reports/FBgn0041596 gene - - - l(2)PJ25 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052278 CG32278 - http://flybase.org/reports/FBgn0052278 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG12032, CG32278" - CG32278 11-Aug-17 DroID_v2017_08 Drer\trmt5 Scer\TRM5 - Xtro\trmt5 Mmus\Trmt5 Hsap\TRMT5 viable FBgn0030951 CG6873 - http://flybase.org/reports/FBgn0030951 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR002108 actin binding ; GO:0003779 | inferred from sequence or structural similarity actin filament depolymerization ; GO:0030042 | inferred from electronic annotation with InterPro:IPR017904 neurogenesis ; GO:0022008 | inferred from mutant phenotype actin cytoskeleton ; GO:0015629 | inferred from electronic annotation with InterPro:IPR017904 "CG6873, adf" "IPR002108:Actin-depolymerising factor homology domain, IPR017904:ADF/Cofilin, IPR029006:ADF-H/Gelsolin-like domain" CG6873 11-Aug-17 DroID_v2017_08 "Drer\cfl1l, Drer\cfl1, Drer\cfl2" Scer\COF1 Cele\unc-60 "Xtro\cfl2, Xtro\cfl1, Xtro\dstn" "Mmus\Cfl2, Mmus\Cfl1, Mmus\Dstn" "Hsap\CFL1, Hsap\DSTN, Hsap\CFL2" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0026085 dgt4 dim gamma-tubulin 4 http://flybase.org/reports/FBgn0026085 FBgn0062844 protein_coding_gene - mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype spindle ; GO:0005819 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay HAUS complex ; GO:0070652 | colocalizes_with inferred from direct assay "EG0007.10, EG:EG0007.10, BcDNA:SD26403, Dgt4, dgt4, CG4865, msd3" - CG4865 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC18659 I 2.256989241 1.348787123 0.236628882 0.218943915 -0.369896802 -0.98703201 FBgn0039395 CG14546 - http://flybase.org/reports/FBgn0039395 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14546 - CG14546 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060554 l(3)S097416 lethal (3) S097416 http://flybase.org/reports/FBgn0060554 gene - - - "0974/16, l(3)S097416" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029849 Efr ER GDP-fucose transporter http://flybase.org/reports/FBgn0029849 protein_coding_gene UDP-glucose transmembrane transporter activity ; GO:0005460 | NOT inferred from direct assay CMP-N-acetylneuraminate transmembrane transporter activity ; GO:0005456 | NOT inferred from direct assay UDP-glucuronic acid transmembrane transporter activity ; GO:0005461 | NOT inferred from direct assay GDP-fucose transmembrane transporter activity ; GO:0005457 | inferred from direct assay UDP-N-acetylglucosamine transmembrane transporter activity ; GO:0005462 | inferred from sequence or structural similarity with UniProtKB:Q969S0 UDP-xylose transmembrane transporter activity ; GO:0005464 | inferred from sequence or structural similarity with UniProtKB:Q969S0 UDP-xylose transmembrane transporter activity ; GO:0005464 | inferred from direct assay UDP-N-acetylglucosamine transmembrane transporter activity ; GO:0005462 | inferred from direct assay GDP-mannose transmembrane transporter activity ; GO:0005458 | NOT inferred from direct assay "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR013657 protein O-linked fucosylation ; GO:0036066 | inferred from direct assay CMP-N-acetylneuraminate transport ; GO:0015782 | NOT inferred from direct assay UDP-xylose transport ; GO:0015790 | inferred from sequence or structural similarity with UniProtKB:Q969S0 UDP-xylose transport ; GO:0015790 | inferred from direct assay GDP-fucose import into endoplasmic reticulum lumen ; GO:0036084 | inferred by curator from GO:0005457,GO:0005783 UDP-N-acetylglucosamine transport ; GO:0015788 | inferred from direct assay GDP-mannose transport ; GO:0015784 | NOT inferred from direct assay UDP-glucuronic acid transport ; GO:0015787 | NOT inferred from direct assay heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from direct assay GDP-fucose transport ; GO:0015783 | inferred from direct assay UDP-glucose transport ; GO:0015786 | NOT inferred from direct assay UDP-N-acetylglucosamine transport ; GO:0015788 | inferred from sequence or structural similarity with UniProtKB:Q969S0" integral component of membrane ; GO:0016021 | inferred from sequence model endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with UniProtKB:Q969S0 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 "Efr, CG3774" IPR013657:UAA transporter CG3774 11-Aug-17 DroID_v2017_08 Drer\slc35b4 Scer\YEA4 "Cele\nstp-2, Cele\nstp-1" Xtro\slc35b4 Mmus\Slc35b4 Hsap\SLC35B4 "lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" "wing vein L5,posterior crossvein" FBgn0041176 Ubx::Hmed\Lox4 Lox4 http://flybase.org/reports/FBgn0041176 engineered_fusion_gene - - - Ubx::Hmed\Lox4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "leg,ectopic,antenna,haltere,wing,embryonic epidermis,abdominal 1 ventral denticle belt,Kolbchen" FBgn0259380 EP-450 - http://flybase.org/reports/FBgn0259380 gene - - - EP-450 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing" FBgn0004917 rls restless http://flybase.org/reports/FBgn0004917 - gene - - - rls - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective FBgn0051239 CG31239 - http://flybase.org/reports/FBgn0051239 protein_coding_gene - - - CG31239 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067407 Or98P Odorant receptor 98a pseudogene http://flybase.org/reports/FBgn0067407 pseudogene_attribute - - - "CR33345, Or98P" - CR33345 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22948 K 0.159327548 -0.158541804 -0.471928784 0.383432689 -0.130482054 1.615035794 FBgn0005434 l(1)v11 lethal (1) v11 http://flybase.org/reports/FBgn0005434 - gene - - - "l(1)11, l(1)v11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024901 anon-a25 anon-a25 http://flybase.org/reports/FBgn0024901 - repeat_region - - - "a25, anon-a25" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261373 CG33228 - http://flybase.org/reports/FBgn0261373 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4806, CG33228, l(2)SH0542, l(2)SH2 0542" - CG33228 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,lethal - all die before end of larval stage,some die during third instar larval stage" FBgn0028007 l(3)S115415 lethal (3) S115415 http://flybase.org/reports/FBgn0028007 gene - - - "l(3)S115415, l(3)s036809" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0053773 CG33773 - http://flybase.org/reports/FBgn0053773 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1061, CG33773" IPR010512:Protein of unknown function DUF1091 CG33773 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0085535 CG40923 - http://flybase.org/reports/FBgn0085535 protein_coding_gene - - - CG40923 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265511 CR44373 - http://flybase.org/reports/FBgn0265511 non_protein_coding_gene - - - CR44373 - CR44373 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040841 CG13286 - http://flybase.org/reports/FBgn0040841 protein_coding_gene - - - CG13286 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065283 l(2)SH2024 lethal (2) SH2024 http://flybase.org/reports/FBgn0065283 gene - - - "l(2)SH2024, l(2)SH2 2024" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262817 CG43188 - http://flybase.org/reports/FBgn0262817 protein_coding_gene - - - "CG43188, noncoding_5956, MIP03057" - CG43188 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034402 CG15084 - http://flybase.org/reports/FBgn0034402 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15084 IPR007590:CWC16 protein CG15084 11-Aug-17 DroID_v2017_08 "Drer\ccdc94, Drer\ccdc130" Scer\YJU2 "Cele\F37C12.1, Cele\ZK1307.9" Xtro\ccdc130 "Mmus\Ccdc94, Mmus\Ccdc130" "Hsap\CCDC94, Hsap\CCDC130" FBgn0031816 CG16947 - http://flybase.org/reports/FBgn0031816 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR008913 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:17479 zinc ion binding ; GO:0008270 | inferred from sequence model" protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:17479 ubiquitin ligase complex ; GO:0000151 | inferred from sequence or structural similarity with HGNC:17479 "CG16947, anon-EST:Posey20" "IPR001841:Zinc finger, RING-type, IPR008913:Zinc finger, CHY-type, IPR017921:Zinc finger, CTCHY-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG16947 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-24l11.2, Drer\rchy1" Scer\HOT13 - "Xtro\rchy1, Xtro\foxo1" Mmus\Rchy1 Hsap\RCHY1 FBgn0015430 l(1)2BCb lethal (1) 2BCb http://flybase.org/reports/FBgn0015430 - gene - - - l(1)2BCb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263546 mir-4985 mir-4985 stem loop http://flybase.org/reports/FBgn0263546 miRNA_gene - - - "mir-4985, dme-mir-4985, CR43531" - CR43531 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033032 kune kune-kune http://flybase.org/reports/FBgn0033032 protein_coding_gene - "establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | NOT inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004031 pleated septate junction ; GO:0005919 | inferred from direct assay septate junction ; GO:0005918 | inferred from sequence or structural similarity with sinu septate junction ; GO:0005918 | inferred from direct assay "Kune, CG1298, kune" IPR004031:PMP-22/EMP/MP20/Claudin superfamily CG1298 11-Aug-17 DroID_v2017_08 "Drer\lim2.4, Drer\cacng3a" - "Cele\str-73, Cele\srd-31" - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval dorsal trunk,embryonic/larval tracheal system" FBgn0043487 ins inseparabile http://flybase.org/reports/FBgn0043487 gene - - - ins - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260616 2L3194 - http://flybase.org/reports/FBgn0260616 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3194 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0069994 BG01856 BG01856 http://flybase.org/reports/FBgn0069994 gene - - - BG01856 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0001466 l(1)7Fc lethal (1) 7Fc http://flybase.org/reports/FBgn0001466 - gene - - - "l(1)GE208, JC18, l(1)7Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0011859 tRNA:Gly-GCC-1-1 transfer RNA:Glycine-GCC 1-1 http://flybase.org/reports/FBgn0011859 "FBgn0003776, FBgn0051667, FBgn0060226" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "phe-tRNA-2, tRNA:gly3:22BCa, AE002638.trna7-GlyGCC, tRNA:G:GCC:AE002638-a, CR31667, tRNA[Gly-GCC], chr2L.trna40-GlyGCC, tRNA-Gly-GCC-1-1, tRNA:Gly-GCC-1-1, tRNA:G3:22BCa, GGC" - CR31667 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261524 lic licorne http://flybase.org/reports/FBgn0261524 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement mitogen-activated protein kinase kinase kinase binding ; GO:0031435 | inferred from physical interaction with Mekk1 protein kinase activity ; GO:0004672 | inferred from direct assay MAP kinase kinase activity ; GO:0004708 | traceable author statement MAP kinase kinase activity ; GO:0004708 | inferred from direct assay receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 activation of MAPK activity ; GO:0000187 | inferred from direct assay positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype inferred from genetic interaction with gig MAPK cascade ; GO:0000165 | inferred from direct assay mucosal immune response ; GO:0002385 | inferred from mutant phenotype oocyte axis specification ; GO:0007309 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | non-traceable author statement positive regulation of protein phosphorylation ; GO:0001934 | inferred from genetic interaction with gig protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from genetic interaction with Ask1 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003664 "p38, Mkk3, MKK3, D-MKK3, MEK3/MKK3, CG12244, DMKK3, p38MAPKK, DMKK3/lic, DMEK3, Mek3, l(1)G0252, Mpk3, lic, dMKK3, DmMKK3, MEK3" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG12244 11-Aug-17 DroID_v2017_08 "Drer\map2k7, Drer\map2k4a, Drer\map2k4b, Drer\map2k2a, Drer\map2k6" "Scer\PBS2, Scer\STE7" "Cele\sek-1, Cele\sek-3, Cele\mkk-4, Cele\sek-4, Cele\mek-1, Cele\mek-2, Cele\sek-5, Cele\jkk-1" "Xtro\map2k7, Xtro\map2k4, Xtro\map2k6, Xtro\map2k1" "Mmus\Map2k3, Mmus\Map2k2, Mmus\Map2k1, Mmus\Map2k6, Mmus\Map2k4, Mmus\Map2k7" "Hsap\MAP2K2, Hsap\LOC100996792, Hsap\MAP2K3, Hsap\MAP2K7, Hsap\MAP2K1, Hsap\MAP2K6, Hsap\MAP2K4" " oogenesis stage | stage >=S10 && adult stage | female , embryonic stage , oogenesis stage | stage >=S7 && adult stage | female " " oocyte

, anterior embryonic/larval midgut

, nurse cell

, posterior embryonic/larval midgut

,

ubiquitous " FBgn0011483 l(3)neo50 lethal (3) neo50 http://flybase.org/reports/FBgn0011483 - gene - - - l(3)neo50 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003546 su(b) suppressor of black http://flybase.org/reports/FBgn0003546 - gene - - - su(b) - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,fertile,reduced" FBgn0026226 l(1)16Fo lethal (1) 16Fo http://flybase.org/reports/FBgn0026226 - gene - - - "ME-VII, l(1)16Fo" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0017404 dode dorsal deviant http://flybase.org/reports/FBgn0017404 - gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available dode - - 11-Aug-17 DroID_v2017_08 - - - - - - "chordotonal organ & axon | lateral,commissure,longitudinal connective" FBgn0035372 CG12093 - http://flybase.org/reports/FBgn0035372 protein_coding_gene - - - CG12093 IPR021454:Protein of unknown function DUF3105 CG12093 11-Aug-17 DroID_v2017_08 Drer\si:dkey-54n8.2 - Cele\Y41C4A.8 Xtro\tp53i13 Mmus\Trp53i13 Hsap\TP53I13 "viable,fertile,lethal" FBgn0036501 CG7272 - http://flybase.org/reports/FBgn0036501 protein_coding_gene sugar transmembrane transporter activity ; GO:0051119 | inferred from sequence or structural similarity with WB:WBGene00019300 sugar transmembrane transporter activity ; GO:0051119 | inferred from biological aspect of ancestor with PANTHER:PTN000846358 carbohydrate transmembrane transport ; GO:0034219 | inferred from sequence or structural similarity with WB:WBGene00019300 carbohydrate transport ; GO:0008643 | inferred from biological aspect of ancestor with PANTHER:PTN000846358 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with WB:WBGene00019300 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with WB:WBGene00019300 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000846358 CG7272 "IPR018178:Putative SWEET transporter, Insecta, IPR004316:SWEET sugar transporter" CG7272 11-Aug-17 DroID_v2017_08 Drer\slc50a1 Scer\SSN2 "Cele\swt-2, Cele\swt-1, Cele\swt-4, Cele\swt-7, Cele\swt-3, Cele\swt-6, Cele\swt-5" Xtro\slc50a1 Mmus\Slc50a1 Hsap\SLC50A1 "viable,fertile,visible" trichogen cell FBgn0028026 l(3)S103505b lethal (3) S103505b http://flybase.org/reports/FBgn0028026 gene - - - "1035/05, l(3)S103505, l(3)S103505b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029887 CG3198 - http://flybase.org/reports/FBgn0029887 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000271979 "positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002245 inferred from sequence or structural similarity with protein_id:BAA90542 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D mRNA splice site selection ; GO:0006376 | inferred from biological aspect of ancestor with PANTHER:PTN000271979" U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000271979 U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity with SGD:S000002245 inferred from sequence or structural similarity with protein_id:BAA90542 U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000271979 CG3198 IPR004882:Luc7-related CG3198 11-Aug-17 DroID_v2017_08 "Drer\luc7l3, Drer\luc7l, Drer\zgc:158803" Scer\LUC7 "Cele\B0495.8, Cele\C50D2.8, Cele\Y119D3B.12" "Xtro\luc7l, Xtro\luc7l3, Xtro\luc7l2" "Mmus\Luc7l2, Mmus\Luc7l, Mmus\Luc7l3" "Hsap\LUC7L, Hsap\LUC7L3, Hsap\LUC7L2" DRSC18292 K 1.358112281 -0.065196479 0.946636305 -0.197617692 -1.873500318 -1.03340516 FBgn0038451 CG14893 - http://flybase.org/reports/FBgn0038451 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - "CT34717, CG14893" "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG14893 11-Aug-17 DroID_v2017_08 "Drer\far1, Drer\si:dkey-97m3.1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR2, Hsap\FAR1" viable FBgn0083028 snoRNA:Psi18S-525k snoRNA:Psi18S-525k http://flybase.org/reports/FBgn0083028 snoRNA_gene - - - "snoRNA:Psi18S-525k, psi18S-525k, CR34569" - CR34569 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032820 fbp "fructose-1,6-bisphosphatase" http://flybase.org/reports/FBgn0032820 protein_coding_gene "fructose 1,6-bisphosphate 1-phosphatase activity ; GO:0042132 | inferred from biological aspect of ancestor with PANTHER:PTN000168022" "fructose metabolic process ; GO:0006000 | inferred from biological aspect of ancestor with PANTHER:PTN000168022 gluconeogenesis ; GO:0006094 | inferred from biological aspect of ancestor with PANTHER:PTN000168022 fructose 1,6-bisphosphate metabolic process ; GO:0030388 | inferred from biological aspect of ancestor with PANTHER:PTN000168022 fructose 6-phosphate metabolic process ; GO:0006002 | inferred from biological aspect of ancestor with PANTHER:PTN000168022 sucrose biosynthetic process ; GO:0005986 | inferred from biological aspect of ancestor with PANTHER:PTN000168022" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000168034 "FbPase, CG10611, CG31692, fbp" "IPR000146:Fructose-1,6-bisphosphatase class 1, IPR028343:Fructose-1,6-bisphosphatase, IPR020548:Fructose-1,6-bisphosphatase, active site, IPR033391:Fructose-1-6-bisphosphatase class I, N-terminal" CG31692 11-Aug-17 DroID_v2017_08 "Drer\fbp1b, Drer\fbp1a, Drer\fbp2, Drer\erlin2" Scer\FBP1 "Cele\vps-41, Cele\fbp-1" "Xtro\vps41, Xtro\fbp2, Xtro\fbp1" "Mmus\Fbp2, Mmus\Vps41, Mmus\Fbp1" "Hsap\FBP1, Hsap\FBP2" "viable,fertile" FBgn0004696 vt verticals http://flybase.org/reports/FBgn0004696 - gene - - - vt - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050184 CG30184 - http://flybase.org/reports/FBgn0050184 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30184 - CG30184 11-Aug-17 DroID_v2017_08 Drer\pik3c3 Scer\VPS34 - Xtro\pik3c3 Mmus\Pik3c3 Hsap\PIK3C3 "viable,fertile" FBgn0036790 AstC-R1 Allatostatin C receptor 1 http://flybase.org/reports/FBgn0036790 protein_coding_gene somatostatin receptor activity ; GO:0004994 | inferred from electronic annotation with InterPro:IPR000586 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model neuropeptide binding ; GO:0042923 | inferred from biological aspect of ancestor with PANTHER:PTN000659780 allatostatin receptor activity ; GO:0008261 | inferred from direct assay "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger ; GO:0007187 | inferred from biological aspect of ancestor with PANTHER:PTN001200938 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity" neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN001200938 integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0008261 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001200938 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "star1, CG7285, Drostar1, anon-WO0170980.80, anon-WO0170980.79, anon-WO0131005.19, ASTC-R1, AstC-R1, drSTAR1" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000586:Somatostatin receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG7285 11-Aug-17 DroID_v2017_08 "Drer\sstr3, Drer\f2rl1.1, Drer\si:dkey-42l23.2, Drer\LOC556451, Drer\gpr183a, Drer\gpr34a, Drer\LOC100334739, Drer\sstr2b, Drer\sstr5, Drer\LOC564730, Drer\gpr183b, Drer\gpr34b, Drer\si:dkey-216e24.9, Drer\oprd1b, Drer\LOC100333697, Drer\oprd1a, Drer\si:dkey-96n2.3, Drer\si:dkey-165n16.5, Drer\oprk1, Drer\gpr17, Drer\p2ry4, Drer\LOC558520, Drer\f2r, Drer\si:ch211-184m13.4, Drer\oprm1, Drer\mchr1b, Drer\gpr4, Drer\lpar5a, Drer\sstr1a, Drer\cysltr1, Drer\gpr20, Drer\oxgr1a.2, Drer\hcar1-2, Drer\cysltr2a, Drer\mchr1a, Drer\oprl1, Drer\LOC571123, Drer\zgc:194202, Drer\f2rl1.2, Drer\sstr1b, Drer\LOC101883086, Drer\gpr1, Drer\si:zfos-169g10.2, Drer\LOC100535160, Drer\p2ry2.1, Drer\cxcr3.2, Drer\LOC100005512, Drer\bdkrb1, Drer\p2ry1, Drer\hcar1-1, Drer\p2ry2.2, Drer\gpr174, Drer\sstr2a" - "Cele\npr-3, Cele\npr-24, Cele\npr-20, Cele\npr-16, Cele\npr-30, Cele\npr-18, Cele\F36D4.4" "Xtro\p2ry1, Xtro\sstr3, Xtro\cxcr6, Xtro\gpr174, Xtro\p2ry4, Xtro\npbwr1, Xtro\ackr4, Xtro\oprk1, Xtro\f2rl3, Xtro\cysltr1, Xtro\p2ry2, Xtro\sstr5, Xtro\f2rl2, Xtro\LOC100487226, Xtro\sstr2, Xtro\mchr1.1, Xtro\p2ry10, Xtro\oprm1" "Mmus\Gpr1, Mmus\Sstr2, Mmus\Gpr17, Mmus\F2rl2, Mmus\Gpr34, Mmus\Ptgdr2, Mmus\Oprk1, Mmus\Oprl1, Mmus\Gpr82, Mmus\P2ry2, Mmus\Oprm1, Mmus\Sstr3, Mmus\Npbwr1, Mmus\Gpr171, Mmus\Oxgr1, Mmus\P2ry13, Mmus\P2ry1, Mmus\Gpr149, Mmus\Sstr4, Mmus\Gpr87, Mmus\Gpr31b, Mmus\A630033H20Rik, Mmus\Cysltr2, Mmus\F2rl1, Mmus\P2ry10, Mmus\Oprd1, Mmus\P2ry4, Mmus\Hcar2, Mmus\Mchr1, Mmus\Cysltr1, Mmus\Sstr5, Mmus\Sstr1, Mmus\P2ry14, Mmus\Gpr4" "Hsap\SSTR2, Hsap\F2RL2, Hsap\CYSLTR1, Hsap\GPR87, Hsap\SSTR1, Hsap\GPR149, Hsap\OPRM1, Hsap\F2RL1, Hsap\MCHR2, Hsap\GPR183, Hsap\NPBWR1, Hsap\PTGDR2, Hsap\NPBWR2, Hsap\MCHR1, Hsap\GPR171, Hsap\P2RY12, Hsap\SSTR3, Hsap\P2RY14, Hsap\GPR1, Hsap\SUCNR1, Hsap\P2RY1, Hsap\GPR4, Hsap\SSTR4, Hsap\GPR17, Hsap\P2RY2, Hsap\OXGR1, Hsap\SSTR5, Hsap\OPRL1, Hsap\HCAR3, Hsap\P2RY4, Hsap\OPRK1, Hsap\GPR34, Hsap\OPRD1, Hsap\GPR82" " larval stage , adult stage " " larval central nervous system | restricted

, lamina & glial cell

, pars intercerebralis | restricted

, monopolar laminar cell

" viable FBgn0261090 Sytbeta Synaptotagmin beta http://flybase.org/reports/FBgn0261090 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium-dependent phospholipid binding ; GO:0005544 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 regulation of calcium ion-dependent exocytosis ; GO:0017158 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 integral component of membrane ; GO:0016021 | inferred from sequence model "Syt beta, CG3020, CG42333, Syt V, CG13462, sytbeta, dsytbeta, Sytbeta, SytV, Syt13, syt13, SYT-beta" "IPR001565:Synaptotagmin, IPR000008:C2 domain" CG42333 11-Aug-17 DroID_v2017_08 "Drer\syt6a, Drer\syt13, Drer\syt9a, Drer\syt6b, Drer\syt3, Drer\syt10, Drer\syt15, Drer\syt9b" - "Cele\snt-7, Cele\DH11.5, Cele\snt-5" "Xtro\syt3, Xtro\syt6" "Mmus\Syt9, Mmus\Syt15, Mmus\Syt10, Mmus\Syt6, Mmus\Syt13, Mmus\Syt3" "Hsap\SYT9, Hsap\SYT3, Hsap\SYT13, Hsap\SYT6, Hsap\SYT10, Hsap\SYT15" DRSC10351 K 0.204901643 -0.404321491 -0.274063165 -0.54566193 -0.33602231 -1.537949104 FBgn0027944 prg piragua http://flybase.org/reports/FBgn0027944 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "pra, prg" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086286 GS1027 - http://flybase.org/reports/FBgn0086286 gene - - - "GS1027, 1027" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084042 CG41482 - http://flybase.org/reports/FBgn0084042 protein_coding_gene - - - CG41482 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037443 Dmtn Dementin http://flybase.org/reports/FBgn0037443 protein_coding_gene molecular_function ; GO:0003674 | no biological data available brain development ; GO:0007420 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay "anon-WO0118547.375, CG1021, Dmtn, dmtn" IPR019394:Testis-specific protein TEX28/transmembrane and coiled-coil domains protein CG1021 11-Aug-17 DroID_v2017_08 "Drer\tmcc3, Drer\tmcc1a, Drer\tmcc2, Drer\tmcc1b" - Cele\C15H9.4 "Xtro\tmcc1, Xtro\tmcc3, Xtro\tmcc2" "Mmus\Tmcc2, Mmus\Tmcc3, Mmus\Tex28, Mmus\Tmcc1" "Hsap\TMCC1, Hsap\TMCC2, Hsap\TMCC3, Hsap\TEX28" "partially lethal - majority die,recessive,majority die during pupal stage,short lived,visible,neuroanatomy defective,viable" "wing,optic lobe,medulla neuropil" FBgn0039304 CG10425 - http://flybase.org/reports/FBgn0039304 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - CG10425 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG10425 11-Aug-17 DroID_v2017_08 "Drer\spra, Drer\sprb, Drer\kdsr, Drer\pigf" "Scer\TSC10, Scer\GPI11, Scer\LYS2" "Cele\T01G6.10, Cele\Y37E11AM.3" "Xtro\pigf, Xtro\kdsr" "Mmus\Kdsr, Mmus\Pigf" "Hsap\KDSR, Hsap\PIGF" viable FBgn0067648 sd-8 sd-8 http://flybase.org/reports/FBgn0067648 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0061125 l(3)S003601 lethal (3) S003601 http://flybase.org/reports/FBgn0061125 gene - - - "0036/01, l(3)S003601" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039084 CG10175 - http://flybase.org/reports/FBgn0039084 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002168 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10175 "IPR002018:Carboxylesterase, type B, IPR002168:Lipase, GDXG, putative histidine active site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG10175 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-93f2.1, Drer\nlgn1, Drer\nlgn4a, Drer\nlgn3a, Drer\ces3, Drer\cell, Drer\ces2, Drer\nlgn2b, Drer\nlgn2a, Drer\nlgn4b, Drer\nlgn3b, Drer\cel.1" - "Cele\F13H6.3, Cele\K11G9.2, Cele\Y71H2AM.13, Cele\K11G9.1, Cele\T28C12.5, Cele\B0238.7, Cele\F15A8.6, Cele\B0238.1, Cele\C52A10.2, Cele\C52A10.1, Cele\T28C12.4, Cele\F56C11.6, Cele\F07C4.12, Cele\K11G9.3, Cele\ges-1" "Xtro\nlgn4x, Xtro\ces2, Xtro\nlgn3, Xtro\nlgn2, Xtro\bche, Xtro\cel, Xtro\LOC100494782, Xtro\ces3" "Mmus\Ces1d, Mmus\Nlgn2, Mmus\Ces1g, Mmus\Ces2f, Mmus\Ces1f, Mmus\Ces5a, Mmus\Ces2b, Mmus\Ces4a, Mmus\Ces2g, Mmus\Ces1e, Mmus\Ces2c, Mmus\Nlgn1, Mmus\Ces2e, Mmus\Nlgn3, Mmus\Ces2h, Mmus\Ces2a, Mmus\Cel, Mmus\Ces3a, Mmus\Ces3b, Mmus\Ces1b, Mmus\Ces1h, Mmus\Ces1c" "Hsap\NLGN1, Hsap\CEL, Hsap\CES1, Hsap\NLGN2, Hsap\CES4A, Hsap\CES2, Hsap\NLGN4Y, Hsap\CES3, Hsap\CES5A, Hsap\NLGN3, Hsap\NLGN4X" "viable,fertile" FBgn0267014 CR45458 - http://flybase.org/reports/FBgn0267014 pseudogene_attribute - - - CR45458 - CR45458 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034120 CG15710 - http://flybase.org/reports/FBgn0034120 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG15710 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG15710 11-Aug-17 DroID_v2017_08 - - Cele\ces-1 - - - FBgn0034642 CG15674 - http://flybase.org/reports/FBgn0034642 protein_coding_gene - - - CG15674 - CG15674 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0041602 g11 g11 http://flybase.org/reports/FBgn0041602 gene - - - g11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005258 l(3)SG78 lethal (3) SG78 http://flybase.org/reports/FBgn0005258 - gene - - - l(3)SG78 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082673 Fas1::sns Fas1::sns http://flybase.org/reports/FBgn0082673 engineered_fusion_gene - - - Fas1::sns - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261876 Z2-2317 - http://flybase.org/reports/FBgn0261876 gene - sleep ; GO:0030431 | inferred from mutant phenotype - Z2-2317 - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective FBgn0085465 CG34436 - http://flybase.org/reports/FBgn0085465 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "CG34436, CG16918, SPH201" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34436 11-Aug-17 DroID_v2017_08 Drer\f7i - "Cele\svh-1, Cele\try-3" - - - viable FBgn0032720 mRpL13 mitochondrial ribosomal protein L13 http://flybase.org/reports/FBgn0032720 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000166701 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049640 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049640 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9BYD1 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049640 "CG10603, L13, anon-EST:fe3C4, mRpL13, CG10602" IPR005822:Ribosomal protein L13 CG10603 11-Aug-17 DroID_v2017_08 Drer\mrpl13 Scer\MRPL23 Cele\mrpl-13 Xtro\mrpl13 Mmus\Mrpl13 Hsap\MRPL13 "viable,visible" trichogen cell FBgn0044106 E(rst)C408 E(rst)C408 http://flybase.org/reports/FBgn0044106 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C408, E(rst)C408" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022232 l(2)k03002a lethal (2) k03002a http://flybase.org/reports/FBgn0022232 - gene - - - "l(2)k03002, l(2)k03002a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043385 EP566a EP566a http://flybase.org/reports/FBgn0043385 gene - - - "EP0566a, EP566a" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036620 CG4842 - http://flybase.org/reports/FBgn0036620 protein_coding_gene "alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from electronic annotation with InterPro:IPR002424, InterPro:IPR002426" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002424 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - CG4842 "IPR002424:Alcohol dehydrogenase, insect-type, IPR002426:Alcohol dehydrogenase, Ceratitis-type, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site, IPR002347:Short-chain dehydrogenase/reductase SDR" CG4842 11-Aug-17 DroID_v2017_08 "Drer\hpgd, Drer\zgc:56585, Drer\cbr4" Scer\SPS19 "Cele\R05D8.9, Cele\C01G12.5, Cele\T01G6.10, Cele\W03F9.9, Cele\T01G6.1, Cele\C06B8.3" Xtro\hpgd "Mmus\Hpgd, Mmus\Cbr4" "Hsap\CBR4, Hsap\HPGD" viable FBgn0014359 ms(3)HB737 ms(3)HB737 http://flybase.org/reports/FBgn0014359 - gene - - - "ms(2)HB737, ms(3)HB737" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034279 CG18635 - http://flybase.org/reports/FBgn0034279 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR018629 CG18635 IPR018629:XK-related protein CG18635 11-Aug-17 DroID_v2017_08 "Drer\xkr6b, Drer\xkr8.1, Drer\xkr9, Drer\LOC100000884, Drer\xkr8.2, Drer\xkr7, Drer\zgc:198371, Drer\xkr8.3, Drer\xkr6a, Drer\si:ch211-195b13.6" - Cele\ced-8 "Xtro\xkr7, Xtro\xkr4, Xtro\xkr5, Xtro\xkr6" "Mmus\Xkr7, Mmus\Xkr4, Mmus\Xkr6, Mmus\Xkr8, Mmus\Xkr5, Mmus\Xkr9" "Hsap\XKR6, Hsap\XKR4, Hsap\XKR8, Hsap\XKR7, Hsap\XKR5, Hsap\XKR9" viable FBgn0086065 snoRNA:Me28S-G3113a - http://flybase.org/reports/FBgn0086065 snoRNA_gene - - - "snoRNA:Me28S-G3113a, Me28S-Gm3113a, Me-28S-G3113a(Dm3112), CR34694, Dm3112a" - CR34694 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003284 Rsp Responder to Sd http://flybase.org/reports/FBgn0003284 - repeat_region - - - "Rsp, rsp, Ac-SD, Rsp-Sd, Dr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0070018 BG01047 BG01047 http://flybase.org/reports/FBgn0070018 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01047 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,viable,smell perception defective" FBgn0085579 CG41253 - http://flybase.org/reports/FBgn0085579 protein_coding_gene - - - CG41253 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003020 ota7 olfactory trap abnormal 7 http://flybase.org/reports/FBgn0003020 - gene molecular_function ; GO:0003674 | no biological data available chemosensory behavior ; GO:0007635 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ota7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,recessive,smell perception defective,dominant,partially" FBgn0010043 GstD7 Glutathione S transferase D7 http://flybase.org/reports/FBgn0010043 FBgn0038026 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTD7, DmGST26, Gst, CG4371, gstD26, GstD26, GstD7, GSTD7, DmGstd7, gstd7" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG4371 11-Aug-17 DroID_v2017_08 "Drer\eef1g, Drer\mars, Drer\gstt1b, Drer\gstr, Drer\gstt2, Drer\gstt1a, Drer\vars, Drer\eef1e1" "Scer\CAM1, Scer\YGR201C, Scer\GTT2, Scer\TEF4, Scer\GTT1, Scer\URE2" "Cele\gst-34, Cele\gst-35" "Xtro\eef1g, Xtro\eef1e1, Xtro\gstt1" "Mmus\Eef1e1, Mmus\Vars, Mmus\Gstt1, Mmus\Eef1g, Mmus\Gstt2, Mmus\Mars, Mmus\Gstt4, Mmus\Gstt3" "Hsap\GSTT1, Hsap\VARS, Hsap\GSTT2B, Hsap\EEF1E1, Hsap\EEF1G, Hsap\MARS, Hsap\GSTT2" larval stage

"viable,visible" trichogen cell FBgn0277422 l(3)psg19 - http://flybase.org/reports/FBgn0277422 gene - - - "l(3)psg19, psg19" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0064142 shkl shackleton http://flybase.org/reports/FBgn0064142 gene - nuclear axial expansion ; GO:0035191 | inferred from mutant phenotype - shkl - - 11-Aug-17 DroID_v2017_08 - - - - - - "pole cell,maternal effect,cleavage nucleus,centrosome & cleavage nucleus | maternal effect,germline clone" FBgn0014871 Pt1 Protein 1 http://flybase.org/reports/FBgn0014871 - gene - - - Pt1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259176 bun bunched http://flybase.org/reports/FBgn0259176 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000580 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000580 positive regulation of neuroblast proliferation ; GO:0002052 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype decapentaplegic signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp negative regulation of cell fate specification ; GO:0009996 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern tissue regeneration ; GO:0042246 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern" cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000269799 "bun, CG42281, CG5461, EP(2)0488, l(2)k02903, l(2)06475, l(2)05479, l(2)02687, shs, 1550, l(2)00255, TSC-22, l(2)rI043, Tsc22, CG31857, Bun, bnc, BunA, Dm_2L:60722" IPR000580:TSC-22 / Dip / Bun CG42281 11-Aug-17 DroID_v2017_08 "Drer\zgc:153012, Drer\zgc:65895, Drer\zgc:64189, Drer\tsc22d3, Drer\tsc22d1, Drer\tsc22d2" - "Cele\T18D3.7, Cele\C30G4.4, Cele\Y48C3A.12" "Xtro\tsc22d1, Xtro\LOC101732882, Xtro\tsc22d3, Xtro\tsc22d2" "Mmus\Tsc22d1, Mmus\Tsc22d4, Mmus\Tsc22d3, Mmus\Tsc22d2" "Hsap\TSC22D3, Hsap\TSC22D2, Hsap\TSC22D4, Hsap\TSC22D1" pupal stage salivary gland

larval stage | third instar eye-antennal disc

DRSC01255 E 0.822401203 1.070763877 1.561412756 0.428048882 -0.468112426 -0.556152458 FBgn0264347 CR43803 - http://flybase.org/reports/FBgn0264347 non_protein_coding_gene - - - CR43803 - CR43803 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042170 CG18850 - http://flybase.org/reports/FBgn0042170 protein_coding_gene - - - CG18850 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030545 CG11590 - http://flybase.org/reports/FBgn0030545 protein_coding_gene copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN000602692 response to metal ion ; GO:0010038 | inferred from electronic annotation with InterPro:IPR004323 - "BcDNA:GM24986, CG11590" "IPR004323:Divalent ion tolerance protein, CutA, IPR011322:Nitrogen regulatory PII-like, alpha/beta, IPR015867:Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal" CG11590 11-Aug-17 DroID_v2017_08 Drer\zgc:63972 - Cele\F35G12.7 "Xtro\cntd1, Xtro\cuta" "Mmus\Cuta, Mmus\Cutal" Hsap\CUTA lethal FBgn0042119 Cpr65Au Cuticular protein 65Au http://flybase.org/reports/FBgn0042119 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:GH21145, Cpr65Au, CG18778, DmelCpr65Au" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG18778 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\F44F1.4, Cele\math-34" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0267131 CR45571 - http://flybase.org/reports/FBgn0267131 non_protein_coding_gene - - - CR45571 - CR45571 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030682 CG12380 - http://flybase.org/reports/FBgn0030682 protein_coding_gene - - - CG12380 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001001 fs(2)TLM female sterile (2) TLM http://flybase.org/reports/FBgn0001001 - gene - - - fs(2)TLM - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,male sterile" "ovary,ovariole,testis" FBgn0015980 l(2)PC4-F lethal (2) PC4-F http://flybase.org/reports/FBgn0015980 - gene - - - l(2)PC4-F - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010063 M(2)34k M(2)34k http://flybase.org/reports/FBgn0010063 - gene - - - M(2)34k - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262450 mir-312 mir-312 stem loop http://flybase.org/reports/FBgn0262450 miRNA_gene - response to nicotine ; GO:0035094 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cellular response to nitric oxide ; GO:0071732 | inferred from direct assay - "mir-312, dme-mir-312, miR-312, 312, CR43017, CR33616, Dme-miR-312, dme-miR-312, mIR-312" - CR43017 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" "wing,wing hair,wing vein,sensillum campaniformium,ectopic,wing sensillum" FBgn0005736 l(1)TK223 lethal (1) TK223 http://flybase.org/reports/FBgn0005736 - gene - - - "l223, l(1)TK223" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0027187 l(2)60A-E lethal (2) 60A-E http://flybase.org/reports/FBgn0027187 - gene - - - l(2)60A-E - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060304 l(3)S148907 lethal (3) S148907 http://flybase.org/reports/FBgn0060304 gene - - - "1489/07, l(3)S148907" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259395 C67 - http://flybase.org/reports/FBgn0259395 gene - - - C67 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta,ectopic" FBgn0033268 Obp44a Odorant-binding protein 44a http://flybase.org/reports/FBgn0033268 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model extracellular region ; GO:0005576 | inferred from direct assay "CG2297, 44a, bs11e05.y1, anon-EST:ParkEST107, Obp44a, DmelObp44a, obp44a" IPR006170:Pheromone/general odorant binding protein CG2297 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC06838 K 1.363238525 0.049177845 -0.346613267 0.092470403 -0.705920768 2.261098541 FBgn0034753 CG2852 - http://flybase.org/reports/FBgn0034753 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular region ; GO:0005576 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay CG2852 "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG2852 11-Aug-17 DroID_v2017_08 "Drer\ppig, Drer\ppil6, Drer\LOC100333141, Drer\si:ch1073-55a19.2, Drer\ppib, Drer\ppid, Drer\ppiaa, Drer\ppiab, Drer\ppie, Drer\nktr, Drer\ppih" "Scer\CPR4, Scer\CPR5, Scer\CPR8, Scer\CPR2" "Cele\cyn-1, Cele\cyn-6, Cele\cyn-9, Cele\cyn-5, Cele\cyn-3, Cele\cyn-8, Cele\cyn-2, Cele\cyn-11" "Xtro\ppil6, Xtro\ppic, Xtro\ppib, Xtro\ppid, Xtro\ppie, Xtro\ranbp2, Xtro\ppia, Xtro\ppih, Xtro\nktr" "Mmus\Ppig, Mmus\Ppie, Mmus\Ppif, Mmus\Ppia, Mmus\Ranbp2, Mmus\Ppih, Mmus\Ppib, Mmus\Ppil6, Mmus\Ppic, Mmus\Nktr, Mmus\Ppid" "Hsap\NKTR, Hsap\PPIB, Hsap\RGPD4, Hsap\RGPD5, Hsap\PPIAL4A, Hsap\PPIA, Hsap\PPIF, Hsap\PPIH, Hsap\RGPD3, Hsap\RGPD8, Hsap\PPIL6, Hsap\RGPD2, Hsap\PPIE, Hsap\PPIC, Hsap\PPIG, Hsap\RANBP2, Hsap\PPIAL4G, Hsap\RGPD1, Hsap\RGPD6, Hsap\LOC105371242, Hsap\PPID, Hsap\PPIAL4C, Hsap\PPIAL4D" viable FBgn0033732 CG13157 - http://flybase.org/reports/FBgn0033732 protein_coding_gene - - - CG13157 - CG13157 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027549 CG7927 - http://flybase.org/reports/FBgn0027549 FBgn0046458 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:29181 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001099565" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN001099565 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:29181 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:29181 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001099565 "BcDNA:GH11023, anon-WO0172774.138, CG7927" "IPR006994:Transcription factor 25, IPR011990:Tetratricopeptide-like helical domain" CG7927 11-Aug-17 DroID_v2017_08 Drer\tcf25 Scer\RQC1 Cele\K07A12.1 Xtro\tcf25 Mmus\Tcf25 Hsap\TCF25 viable FBgn0033060 CG7849 - http://flybase.org/reports/FBgn0033060 protein_coding_gene pseudouridine synthase activity ; GO:0009982 | inferred from electronic annotation with InterPro:IPR020103 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR020103 pseudouridine synthesis ; GO:0001522 | inferred from electronic annotation with InterPro:IPR020103 RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR002501 - CG7849 "IPR020103:Pseudouridine synthase, catalytic domain, IPR002501:Pseudouridine synthase II, N-terminal" CG7849 11-Aug-17 DroID_v2017_08 "Drer\trub2, Drer\trub1" Scer\PUS4 "Cele\Y43B11AR.3, Cele\K01G5.5" "Xtro\trub2, Xtro\trub1" "Mmus\Trub1, Mmus\Trub2" "Hsap\TRUB2, Hsap\TRUB1" "viable,visible" trichogen cell FBgn0019850 anon-XIV anon-XIV http://flybase.org/reports/FBgn0019850 - gene - - - "XIV, anon-XIV" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027647 l(2)dC9 lethal (2) dC9 http://flybase.org/reports/FBgn0027647 - gene - - - "P368, l(2)dC9" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003693 tha thin arched http://flybase.org/reports/FBgn0003693 - gene - - - tha - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male,poor,male fertile" "macrochaeta,wing" FBgn0004548 l(4)102CDt lethal (4) 102CDt http://flybase.org/reports/FBgn0004548 - gene - - - "l(4)35, l(4)102CDt" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028055 l(3)S094603 lethal (3) S094603 http://flybase.org/reports/FBgn0028055 gene - - - "0946/03, l(3)S094603" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043592 E(ro[DOM])3222 E(ro[DOM])3222 http://flybase.org/reports/FBgn0043592 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available E(ro[DOM])3222 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028047 l(3)S096611 lethal (3) S096611 http://flybase.org/reports/FBgn0028047 gene - - - "0966/11, l(3)S096611" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265862 CR44651 - http://flybase.org/reports/FBgn0265862 non_protein_coding_gene - - - "lincRNA.365, CR44651" - CR44651 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037129 CG14565 - http://flybase.org/reports/FBgn0037129 protein_coding_gene - - - CG14565 - CG14565 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0022293 l(1)M95.1 lethal (1) M95.1 http://flybase.org/reports/FBgn0022293 - gene - - - "M95.1, l(1)M95.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010638 Sec61beta Sec61 beta subunit http://flybase.org/reports/FBgn0010638 FBgn0033947 protein_coding_gene ARF guanyl-nucleotide exchange factor activity ; GO:0005086 | inferred from biological aspect of ancestor with PANTHER:PTN001004493 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001004493 "posttranslational protein targeting to membrane, translocation ; GO:0031204 | inferred from biological aspect of ancestor with PANTHER:PTN001004493 SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616 | inferred from biological aspect of ancestor with PANTHER:PTN001004493 negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype" Sec61 translocon complex ; GO:0005784 | inferred from electronic annotation with InterPro:IPR030671 endoplasmic reticulum Sec complex ; GO:0031205 | inferred from biological aspect of ancestor with PANTHER:PTN001004493 endomembrane system ; GO:0012505 | inferred from direct assay "Sec61, DSec61beta, l(2)07214, Sec61beta, CG10130, sec61beta, Secbeta61, sec61b, Sec1, dSec61beta" "IPR016482:Protein transport protein SecG/Sec61-beta/Sbh, IPR030671:Protein transport Sec61-beta/Sbh" CG10130 11-Aug-17 DroID_v2017_08 Drer\sec61b "Scer\SBH1, Scer\SBH2" Cele\Y38F2AR.9 Xtro\sec61b Mmus\Sec61b Hsap\SEC61B "lethal,recessive,partially,rescuable maternal effect,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,wild-type" "dorsal appendage,egg,chorion,embryonic/first instar larval cuticle,leg,germline clone,head,abdomen,posterior,denticle belt,epicuticle,endocuticle,embryonic/larval trachea,eye,somatic clone,ommatidium,rhabdomere,tarsal segment,lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0032635 CG15141 - http://flybase.org/reports/FBgn0032635 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965, InterPro:IPR003126" - - "BEST:LD24839, CG15141, UBR7" "IPR003126:Zinc finger, UBR-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15141 11-Aug-17 DroID_v2017_08 "Drer\ubr7, Drer\LOC100329344" - Cele\T22C1.1 Xtro\ubr7 Mmus\Ubr7 Hsap\UBR7 viable FBgn0050442 CG30442 - http://flybase.org/reports/FBgn0050442 protein_coding_gene - - - "NEST:bs03e05, BcDNA:AT17684, CG30442" IPR009882:Gypsy - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267826 CR46147 - http://flybase.org/reports/FBgn0267826 non_protein_coding_gene - - - CR46147 - CR46147 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027529 tapas tapas http://flybase.org/reports/FBgn0027529 - protein_coding_gene - negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype piRNA biosynthetic process ; GO:1990511 | inferred from mutant phenotype inferred from genetic interaction with tej perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay "BcDNA:LD21403, CG8920, tapas, tap" "IPR025605:OST-HTH/LOTUS domain, IPR002999:Tudor domain" CG8920 11-Aug-17 DroID_v2017_08 "Drer\tdrd7a, Drer\tdrd1, Drer\tdrd5, Drer\si:dkeyp-93d12.1, Drer\tdrkh, Drer\sb:cb829" - - "Xtro\tdrkh, Xtro\tdrd7" "Mmus\Rnf17, Mmus\Tdrd1, Mmus\Tdrkh, Mmus\Tdrd7, Mmus\Tdrd5" "Hsap\TDRD7, Hsap\TDRD1, Hsap\TDRD5, Hsap\TDRKH" "viable,fertile" FBgn0017380 l(1)7-103 lethal (1) 7-103 http://flybase.org/reports/FBgn0017380 - gene - - - "7-103, l(1)7-103" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030520 Pdcd4 Programmed cell death 4 http://flybase.org/reports/FBgn0030520 protein_coding_gene - germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from mutant phenotype positive regulation of stem cell differentiation ; GO:2000738 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "Pdcd4, CG10990" "IPR003891:Initiation factor eIF-4 gamma, MA3, IPR016024:Armadillo-type fold" CG10990 11-Aug-17 DroID_v2017_08 "Drer\pdcd4a, Drer\pdcd4b" - - Xtro\pdcd4 Mmus\Pdcd4 Hsap\PDCD4 "viable,female fertile,male fertile,long lived,starvation stress response defective,female limited,temperature response defective,locomotor behavior defective" germarium FBgn0267645 CR45983 - http://flybase.org/reports/FBgn0267645 non_protein_coding_gene - - - CR45983 - CR45983 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263568 mir-4946 mir-4946 stem loop http://flybase.org/reports/FBgn0263568 miRNA_gene - - - "mir-4946, dme-mir-4946, CR43553" - CR43553 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260018 diplomatico diplomatico http://flybase.org/reports/FBgn0260018 gene - - - diplomatico - - 11-Aug-17 DroID_v2017_08 - - - - - - chorion | germline clone FBgn0082929 snoRNA:Me28S-G2703c snoRNA:Me28S-G2703c http://flybase.org/reports/FBgn0082929 snoRNA_gene - - - "snoRNA:Me28S-G2703c, Me28S-Gm2703c, CR34541, Me28S-G2703, Me28S-G2703c" - CR34541 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014854 htl::tor htl::tor http://flybase.org/reports/FBgn0014854 - engineered_fusion_gene - - - "Fr1::tor, htl::tor" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,ectopic,wing cell" FBgn0263475 snoRNA:CG16892-a - http://flybase.org/reports/FBgn0263475 snoRNA_gene - - - snoRNA:CG16892-a - CR43590 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036237 viaf viral IAP-associated factor http://flybase.org/reports/FBgn0036237 protein_coding_gene queuine tRNA-ribosyltransferase activity ; GO:0008479 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000239043 regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043281 | inferred from sequence or structural similarity with UniProtKB:Q9H2J4 queuosine biosynthetic process ; GO:0008616 | inferred from biological aspect of ancestor with PANTHER:PTN000239043 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9H2J4 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000239043 "VIAF, CG18593, viaf1, anon-WO0134798.18, anon-WO0134798.17, viaf, Viaf" "IPR012336:Thioredoxin-like fold, IPR024253:Phosducin, thioredoxin-like domain" CG18593 11-Aug-17 DroID_v2017_08 Drer\pdcl3 Scer\PLP2 - Xtro\pdcl3 "Mmus\Pdcl2, Mmus\Pdcl3" "Hsap\PDCL3, Hsap\PDCL2" FBgn0265608 CG44426 - http://flybase.org/reports/FBgn0265608 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44426, lincRNA.1032" - CG44426 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067373 l(2)NC139 lethal (2) NC139 http://flybase.org/reports/FBgn0067373 gene - - - l(2)NC139 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024291 Sirt1 Sirtuin 1 http://flybase.org/reports/FBgn0024291 FBgn0046250 protein_coding_gene NAD+ binding ; GO:0070403 | inferred from electronic annotation with InterPro:IPR003000 protein deacetylase activity ; GO:0033558 | inferred from mutant phenotype histone deacetylase activity ; GO:0004407 | inferred from direct assay NAD-dependent histone deacetylase activity ; GO:0017136 | inferred from direct assay histone deacetylase activity ; GO:0004407 | inferred from mutant phenotype transcription factor binding ; GO:0008134 | inferred from physical interaction with nej "regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay histone deacetylation ; GO:0016575 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype positive regulation of feeding behavior ; GO:2000253 | inferred from mutant phenotype inferred from genetic interaction with mnb protein deacetylation ; GO:0006476 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | NOT inferred from mutant phenotype regulation of response to ethanol ; GO:1901416 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype regulation of histone acetylation ; GO:0035065 | inferred from mutant phenotype histone deacetylation ; GO:0016575 | inferred from direct assay" nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "dSir2, DSir2, SIR2, Sir2L, dsir2, dmSRT406, CG5216, dSIR2, D.mel1, BEST:LD38188, l(2)05326, Sir2, sir2, Sirt1" "IPR003000:Sirtuin family, IPR029035:DHS-like NAD/FAD-binding domain, IPR026590:Sirtuin family, catalytic core domain" CG5216 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-103i16.6, Drer\LOC100536119, Drer\sirt2, Drer\sirt1, Drer\sirt5, Drer\sirt3" "Scer\HST1, Scer\HST3, Scer\HST2, Scer\HST4, Scer\SIR2" Cele\sir-2.1 "Xtro\sirt5, Xtro\sirt1" "Mmus\Sirt5, Mmus\Sirt1, Mmus\Sirt3, Mmus\Sirt2" "Hsap\SIRT5, Hsap\SIRT3, Hsap\SIRT1" "lethal - all die before end of embryonic stage,some die during embryonic stage,short lived,long lived,male limited,female limited,viable,RU486 conditional,suppressor of variegation,dominant,non-suppressor of variegation,male,female,fertile,hypoactive,conditional,chemical resistant,enhancer of variegation,feeding behavior defective,visible,eye color defective,increased cell death,lethal,partially lethal - majority die,some die during pupal stage" "chromatinda.G32,nucleolusda.G32,eye,eye disc | third instar larval stage,wing" FBgn0085220 Ufm1 Ubiquitin-fold modifier 1 http://flybase.org/reports/FBgn0085220 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to endoplasmic reticulum stress ; GO:0034976 | inferred from sequence or structural similarity with HGNC:20597 locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype protein K69-linked ufmylation ; GO:1990592 | inferred from biological aspect of ancestor with PANTHER:PTN000406181 synapse organization ; GO:0050808 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000406181 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:20597 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000406181 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:20597 "CG34191, Ufm1, dUFM1" "IPR005375:Ubiquitin-fold modifier 1, IPR029071:Ubiquitin-related domain" CG34191 11-Aug-17 DroID_v2017_08 Drer\ufm1 - Cele\ufm-1 Xtro\ufm1 Mmus\Ufm1 Hsap\UFM1 FBgn0020326 anon-72Ea anon-72Ea http://flybase.org/reports/FBgn0020326 - gene - - - "4A11, anon-72Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014851 Eig71Ek Eig71Ek http://flybase.org/reports/FBgn0014851 - protein_coding_gene - defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 metamorphosis ; GO:0007552 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model "L71, CG7325, L71-11, Eig71Ek, EIG71-K" IPR003475:Insect protein of unknown function CG7325 11-Aug-17 DroID_v2017_08 - - Cele\W08F4.10 - Mmus\Jag2 - FBgn0265641 CR44448 - http://flybase.org/reports/FBgn0265641 non_protein_coding_gene - - - CR44448 - CR44448 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037327 PEK pancreatic eIF-2alpha kinase http://flybase.org/reports/FBgn0037327 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement elongation factor-2 kinase activity ; GO:0004686 | inferred from direct assay" regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype PERK-mediated unfolded protein response ; GO:0036499 | inferred from genetic interaction with Dad1 positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype - "CG2087, DPERK, DmPEK, Perk, PERK, PEK, perk, pERK, DpERK, dPERK, pek, Pek, dPerk" "IPR018391:Pyrrolo-quinoline quinone beta-propeller repeat, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR017441:Protein kinase, ATP binding site" CG2087 11-Aug-17 DroID_v2017_08 "Drer\pdik1l, Drer\stk35, Drer\pkz, Drer\eif2ak3, Drer\eif2ak2, Drer\si:ch211-63o20.7, Drer\stk35l" Scer\GCN2 "Cele\Y38E10A.8, Cele\pek-1, Cele\zyg-1" "Xtro\eif2ak2, Xtro\pkr2, Xtro\eif2ak3" "Mmus\Pdik1l, Mmus\Stk35, Mmus\Eif2ak2, Mmus\Eif2ak3" "Hsap\EIF2AK2, Hsap\STK35, Hsap\EIF2AK3, Hsap\PDIK1L" "viable,fertile,mitotic cell cycle defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,conditional" "eye,temperature conditional,eye disc,eye disc posterior to the morphogenetic furrow,conditional" DRSC12361 E -0.196470071 0.339484588 -0.320764194 1.645681995 -0.288232431 0.511247855 FBgn0033582 CG9084 - http://flybase.org/reports/FBgn0033582 protein_coding_gene phospholipid scramblase activity ; GO:0017128 | inferred from biological aspect of ancestor with PANTHER:PTN000582979 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000582979 CG9084 IPR005552:Scramblase CG9084 11-Aug-17 DroID_v2017_08 "Drer\plscr3a, Drer\si:ch211-71m22.1, Drer\LOC100536708, Drer\si:ch73-206p6.1, Drer\si:ch211-71m22.5, Drer\plscr3b, Drer\LOC100537119, Drer\si:ch211-71m22.3, Drer\si:dkey-62k3.6" Scer\AIM25 "Cele\scrm-4, Cele\K08D10.18, Cele\scrm-2, Cele\scrm-7, Cele\scrm-1, Cele\scrm-6, Cele\scrm-5, Cele\scrm-8, Cele\scrm-3" "Xtro\plscr3, Xtro\plscr1, Xtro\plscr2" "Mmus\Plscr5, Mmus\Plscr1, Mmus\Plscr2, Mmus\Plscr4, Mmus\1700057G04Rik, Mmus\Plscr3" "Hsap\PLSCR3, Hsap\PLSCR2, Hsap\PLSCR5, Hsap\PLSCR1, Hsap\PLSCR4" viable FBgn0036876 CG9451 - http://flybase.org/reports/FBgn0036876 protein_coding_gene acid phosphatase activity ; GO:0003993 | inferred from sequence or structural similarity with HGNC:125 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:125 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:125 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:125 CG9451 "IPR000560:Histidine phosphatase superfamily, clade-2, IPR029630:Venom acid phosphatase Acph-1, IPR029033:Histidine phosphatase superfamily, IPR033379:Histidine acid phosphatase active site" CG9451 11-Aug-17 DroID_v2017_08 "Drer\acp6, Drer\pxylp1, Drer\acp2" - "Cele\pho-10, Cele\ZK809.9, Cele\F26C11.1, Cele\pho-6, Cele\pho-5, Cele\pho-11, Cele\acp-3, Cele\acp-7, Cele\pho-9, Cele\acp-6, Cele\pho-4, Cele\C27A2.12, Cele\ZK792.1, Cele\pho-13, Cele\pho-14, Cele\pho-7, Cele\acp-5, Cele\pho-1, Cele\acp-4, Cele\acp-2, Cele\acp-1, Cele\pho-12, Cele\pho-8" "Xtro\LOC100494856, Xtro\acp2, Xtro\acp6" "Mmus\Pxylp1, Mmus\Acpt, Mmus\Acp6, Mmus\Acpp, Mmus\Acp2" "Hsap\ACPT, Hsap\ACP6, Hsap\ACP2, Hsap\ACPP, Hsap\PXYLP1" viable FBgn0014912 anon-4Ff anon-4Ff http://flybase.org/reports/FBgn0014912 - gene - - - anon-4Ff - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030757 CG9902 - http://flybase.org/reports/FBgn0030757 protein_coding_gene - - - CG9902 - CG9902 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266740 CR45213 - http://flybase.org/reports/FBgn0266740 non_protein_coding_gene - - - CR45213 - CR45213 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266193 ftz-f1::smt3 - http://flybase.org/reports/FBgn0266193 engineered_fusion_gene - - - ftz-f1::smt3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082682 E(ftz)3150 E(ftz)3150 http://flybase.org/reports/FBgn0082682 gene - - - "3150, E(ftz)3150" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0087008 e(y)3 enhancer of yellow 3 http://flybase.org/reports/FBgn0087008 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 chromatin binding ; GO:0003682 | inferred from direct assay "gene silencing ; GO:0016458 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype negative regulation of chromatin silencing ; GO:0031936 | inferred from genetic interaction with Pc" polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay PBAF complex ; GO:0070604 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay euchromatin ; GO:0000791 | inferred from direct assay "l(1)G0084, CG12238, l(1)G0266, l(1)G0381, e(y)[3], l(1)G0409, l(1)G0283, e(y)3, SAYP, sayp" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG12238 11-Aug-17 DroID_v2017_08 Drer\phf10 - Cele\phf-10 Xtro\phf10 "Mmus\Dpf1, Mmus\Phf10" "Hsap\PHF10, Hsap\DPF1" DRSC19450 E -0.421212157 -0.357969731 1.354483158 -2.69363077 -1.410273557 -1.483712065 FBgn0032251 Nse4 Non-SMC element 4 http://flybase.org/reports/FBgn0032251 protein_coding_gene SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000002263 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000002263 Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000002263 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002263 "CG13142, Nse4" "IPR014854:Non-structural maintenance of chromosome element 4, C-terminal, IPR027786:Nse4/EID family" CG13142 11-Aug-17 DroID_v2017_08 Drer\nsmce4a Scer\NSE4 Cele\H21P03.2 Xtro\nsmce4a "Mmus\Eid3, Mmus\Nsmce4a" "Hsap\NSMCE4A, Hsap\EID3" viable FBgn0265418 CR44330 - http://flybase.org/reports/FBgn0265418 non_protein_coding_gene - - - CR44330 - CR44330 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085227 CG34198 - http://flybase.org/reports/FBgn0085227 protein_coding_gene - - - CG34198 - CG34198 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259858 Su(Ste):CR42427 Su(Ste):CR42427 http://flybase.org/reports/FBgn0259858 non_protein_coding_gene - - - "Su(Ste):CR42427, CR42427" - CR42427 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002990 olfA olfactory A http://flybase.org/reports/FBgn0002990 - gene - - - olfA - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,recessive,viable,fertile" FBgn0011113 l(1)Q74 lethal (1) Q74 http://flybase.org/reports/FBgn0011113 FBgn0010210 gene - - - l(1)Q74 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060679 l(3)S076903 lethal (3) S076903 http://flybase.org/reports/FBgn0060679 gene - - - "0769/03, l(3)S076903" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0002818 ms(2)2R male sterile (2) 2R http://flybase.org/reports/FBgn0002818 - gene - - - ms(2)2R - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0010511 l(2)02321 lethal (2) 02321 http://flybase.org/reports/FBgn0010511 - gene - - - l(2)02321 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267630 CR45968 - http://flybase.org/reports/FBgn0267630 non_protein_coding_gene - - - CR45968 - CR45968 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067742 l(1)G0288 lethal (1) G0288 http://flybase.org/reports/FBgn0067742 gene - - - l(1)G0288 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035849 ERR estrogen-related receptor http://flybase.org/reports/FBgn0035849 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628 steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723, InterPro:IPR024178, InterPro:IPR027289 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088, InterPro:IPR024178 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 steroid binding ; GO:0005496 | inferred from electronic annotation with InterPro:IPR024178, InterPro:IPR027289 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement" steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 carbohydrate metabolic process ; GO:0005975 | inferred from direct assay regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P03372 "dERR, CG7404, ERR, NR3B4, Derr" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type, IPR024178:Oestrogen receptor/oestrogen-related receptor, IPR027289:Oestrogen-related receptor" CG7404 11-Aug-17 DroID_v2017_08 "Drer\nr0b2b, Drer\pparg, Drer\pgr, Drer\nr2f6b, Drer\nr2f6a, Drer\nr6a1b, Drer\esr1, Drer\rargb, Drer\pparaa, Drer\esr2a, Drer\raraa, Drer\rxrbb, Drer\nr3c2, Drer\nr2f1a, Drer\nr2c1, Drer\ar, Drer\nr0b2a, Drer\esrrb, Drer\thrab, Drer\nr2f5, Drer\rarab, Drer\esrrga, Drer\esrra, Drer\nr0b1, Drer\nr1i2, Drer\nr2f2, Drer\rxrga, Drer\nr1h5, Drer\nr2f1b, Drer\vdrb, Drer\nr3c1, Drer\esrrd, Drer\nr5a1a, Drer\esr2b, Drer\nr2e3, Drer\pparab, Drer\rxrab, Drer\ppardb, Drer\rxraa, Drer\rxrba, Drer\nr2c2, Drer\pparda, Drer\vdra, Drer\nr1h4, Drer\esrrgb, Drer\nr2e1" - "Cele\nhr-286, Cele\nhr-117, Cele\nhr-16, Cele\nhr-275, Cele\nhr-103, Cele\nhr-125, Cele\nhr-69, Cele\nhr-108, Cele\nhr-132, Cele\nhr-226, Cele\nhr-219, Cele\nhr-55, Cele\nhr-218, Cele\nhr-115, Cele\nhr-70, Cele\nhr-180, Cele\nhr-210, Cele\nhr-231, Cele\nhr-176, Cele\nhr-42, Cele\nhr-50, Cele\nhr-243, Cele\dpr-1, Cele\nhr-140, Cele\nhr-288, Cele\nhr-273, Cele\nhr-65, Cele\nhr-58, Cele\nhr-194, Cele\nhr-178, Cele\nhr-163, Cele\nhr-147, Cele\nhr-106, Cele\nhr-84, Cele\nhr-90, Cele\nhr-271, Cele\nhr-110, Cele\nhr-145, Cele\nhr-45, Cele\nhr-225, Cele\nhr-95, Cele\nhr-212, Cele\nhr-102, Cele\nhr-182, Cele\nhr-211, Cele\nhr-56, Cele\nhr-161, Cele\nhr-170, Cele\nhr-89, Cele\nhr-216, Cele\nhr-135, Cele\nhr-162, Cele\nhr-183, Cele\nhr-53, Cele\nhr-195, Cele\nhr-59, Cele\nhr-213, Cele\nhr-256, Cele\nhr-127, Cele\nhr-177, Cele\nhr-238, Cele\nhr-130, Cele\nhr-133, Cele\nhr-131, Cele\nhr-201, Cele\nhr-43, Cele\nhr-139, Cele\nhr-184, Cele\nhr-193, Cele\nhr-128, Cele\nhr-94, Cele\nhr-237, Cele\nhr-107, Cele\nhr-228, Cele\nhr-190, Cele\nhr-98, Cele\nhr-96, Cele\nhr-62, Cele\nhr-126, Cele\nhr-63, Cele\nhr-19, Cele\nhr-44, Cele\nhr-143, Cele\nhr-99, Cele\nhr-109, Cele\nhr-205, Cele\nhr-150, Cele\nhr-123, Cele\nhr-230, Cele\nhr-202, Cele\nhr-86, Cele\nhr-203, Cele\nhr-12, Cele\nhr-232, Cele\nhr-18, Cele\nhr-179, Cele\nhr-37, Cele\nhr-30, Cele\nhr-112, Cele\nhr-54, Cele\nhr-134, Cele\nhr-142" "Xtro\esr2, Xtro\rxra, Xtro\rxrg, Xtro\rarg, Xtro\ppard, Xtro\vdr, Xtro\rarb, Xtro\nr2e1, Xtro\nr2c2, Xtro\ppara, Xtro\ar, Xtro\rara, Xtro\rxrb, Xtro\nr3c1, Xtro\pgr, Xtro\nr1h2, Xtro\thrb, Xtro\nr2c1, Xtro\nr2f5, Xtro\nr1i2, Xtro\nr2f2, Xtro\nr1h5, Xtro\esrrb, Xtro\nr2e3, Xtro\nr0b1, Xtro\esrrgr, Xtro\esrrg, Xtro\nr2f1, Xtro\nr6a1, Xtro\esr1, Xtro\esrra, Xtro\nr2f6, Xtro\nr0b2, Xtro\nr3c2, Xtro\pparg" "Mmus\Esrra, Mmus\Esrrg, Mmus\Nr3c2, Mmus\Nr0b2, Mmus\Ar, Mmus\Pgr, Mmus\Nr2f2, Mmus\Nr2c2, Mmus\Nr1i2, Mmus\Nr2e3, Mmus\Nr1i3, Mmus\Nr2f1, Mmus\Rarg, Mmus\Rxrb, Mmus\Vdr, Mmus\Esrrb, Mmus\Nr2c1, Mmus\Nr0b1, Mmus\Nr2e1, Mmus\Nr3c1, Mmus\Thrb, Mmus\Nr1h2, Mmus\Nr1h3, Mmus\Esr1, Mmus\Rara, Mmus\Thra, Mmus\Nr1h4, Mmus\Esr2, Mmus\Rxra, Mmus\Nr1h5, Mmus\Rxrg, Mmus\Rarb, Mmus\Nr6a1, Mmus\Ppara, Mmus\Nr2f6, Mmus\Ppard, Mmus\Pparg" "Hsap\ESRRB, Hsap\RARB, Hsap\RXRA, Hsap\NR2F1, Hsap\ESRRG, Hsap\PPARD, Hsap\NR1I3, Hsap\PPARG, Hsap\VDR, Hsap\NR2F2, Hsap\NR1H3, Hsap\NR3C1, Hsap\THRB, Hsap\ESR1, Hsap\RARG, Hsap\NR2C2, Hsap\NR2E1, Hsap\ESR2, Hsap\AR, Hsap\PGR, Hsap\PPARA, Hsap\NR6A1, Hsap\NR1H2, Hsap\ESRRA, Hsap\RXRG, Hsap\RARA, Hsap\NR1H4, Hsap\RXRB, Hsap\NR3C2, Hsap\THRA, Hsap\NR2F6, Hsap\NR0B1, Hsap\NR0B2, Hsap\NR1I2, Hsap\NR2C1" "lethal - all die before end of second instar larval stage,some die during second instar larval stage" FBgn0020557 bb-Psi bb-Psi http://flybase.org/reports/FBgn0020557 - pseudogene_attribute - - - "PsirDNA, bb-Psi" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266039 CR44804 - http://flybase.org/reports/FBgn0266039 non_protein_coding_gene - - - "CR44804, lincRNA.223" - CR44804 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264401 FCG-D - http://flybase.org/reports/FBgn0264401 gene - - - FCG-D - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0005504 l(2)24EFb lethal (2) 24EFb http://flybase.org/reports/FBgn0005504 - gene - - - "l(2)Gr.II, l(2)24EFb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060594 l(3)S092302 lethal (3) S092302 http://flybase.org/reports/FBgn0060594 gene - - - "0923/02, l(3)S092302" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0284436 CCT8 Chaperonin containing TCP1 subunit 8 http://flybase.org/reports/FBgn0284436 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012721 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000144200 microtubule associated complex ; GO:0005875 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CCT8, cct8, CG8258, TCP-1theta, Tcp1-theta, Q7K3J0_DROME, l(2)03996, TCP1-theta" "IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012721:T-complex protein 1, theta subunit, IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG8258 11-Aug-17 DroID_v2017_08 Drer\cct8 Scer\CCT8 Cele\cct-8 Xtro\cct8 "Mmus\Bbs12, Mmus\Cct8, Mmus\Cct8l1" "Hsap\CCT8L2, Hsap\CCT8, Hsap\BBS12" FBgn0015293 Sebp3 Secretion enhancer-binding protein 3 http://flybase.org/reports/FBgn0015293 - gene transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from genetic interaction with Sgs4 nucleus ; GO:0005634 | inferred from direct assay "SEBP3, Sebp3" - - 11-Aug-17 DroID_v2017_08 - - - - - - larval stage | third instar embryonic/larval salivary gland

FBgn0001707 l(1)ESHS28 lethal (1) ESHS28 http://flybase.org/reports/FBgn0001707 - gene - - - l(1)ESHS28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033539 Git G protein-coupled receptor kinase interacting ArfGAP http://flybase.org/reports/FBgn0033539 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 GTPase activator activity ; GO:0005096 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with stnB protein complex scaffold ; GO:0032947 | inferred from mutant phenotype synaptic vesicle recycling ; GO:0036465 | inferred from mutant phenotype protein localization to presynapse ; GO:1905383 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype positive regulation of hippo signaling ; GO:0035332 | inferred from genetic interaction with hpo regulation of GTPase activity ; GO:0043087 | inferred from sequence model synaptic vesicle cycle ; GO:0099504 | inferred from mutant phenotype regulation of organ growth ; GO:0046620 | inferred from genetic interaction with Git inferred from genetic interaction with hpo cell leading edge ; GO:0031252 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoskeleton of presynaptic active zone ; GO:0048788 | colocalizes_with inferred from direct assay "CT37209, Git, git, CG16728, dgit, arfgap2, dGit, GIT" "IPR001164:Arf GTPase activating protein, IPR002110:Ankyrin repeat, IPR013724:GIT, Spa2 homology (SHD) domain, IPR020683:Ankyrin repeat-containing domain, IPR022018:ARF GTPase-activating protein GIT1, C-terminal" CG16728 11-Aug-17 DroID_v2017_08 "Drer\git1, Drer\git2b, Drer\git2a" "Scer\AGE1, Scer\SPA2" Cele\git-1 "Xtro\git1, Xtro\git2" "Mmus\Git2, Mmus\Git1" "Hsap\GIT1, Hsap\AGAP2, Hsap\GIT2" "partially lethal - majority die,recessive" "wing,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,A1-7 ventral acute muscle 3,lateral transverse muscle,A1-7 lateral oblique muscle 1" FBgn0001069 Fs(3)Var Female sterile (3) Varas http://flybase.org/reports/FBgn0001069 - gene - - - "Var, Fs(3)Varas, Fs(3)Sz24, Fs(3)Var" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" female pronucleus | maternal effect FBgn0026610 AT21 AT21 http://flybase.org/reports/FBgn0026610 - gene - - - AT21 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038208 CG14355 - http://flybase.org/reports/FBgn0038208 protein_coding_gene - - - CG14355 "IPR031949:Domain of unknown function DUF4776, IPR031992:Domain of unknown function DUF4788" CG14355 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069112 mus218 mutagen-sensitive 218 http://flybase.org/reports/FBgn0069112 gene - - - mus218 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0032364 CG4970 - http://flybase.org/reports/FBgn0032364 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32953, anon-WO0140519.184, CG4970" IPR025254:Domain of unknown function DUF4201 CG4970 11-Aug-17 DroID_v2017_08 - Scer\SLK19 - - - Hsap\CCDC96 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0265258 gbb::Hsap\BMP7 - http://flybase.org/reports/FBgn0265258 engineered_fusion_gene - - - gbb::Hsap\BMP7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070026 BG00378 BG00378 http://flybase.org/reports/FBgn0070026 gene - - - BG00378 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0037070 CG11309 - http://flybase.org/reports/FBgn0037070 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11309 "IPR000073:Alpha/beta hydrolase fold-1, IPR018247:EF-Hand 1, calcium-binding site, IPR029058:Alpha/Beta hydrolase fold" CG11309 11-Aug-17 DroID_v2017_08 Drer\serhl Scer\YGR015C "Cele\abhd-11.2, Cele\abhd-11.1, Cele\W01A11.1, Cele\abhd-5.1" "Xtro\serhl2, Xtro\serhl" Mmus\Serhl Hsap\SERHL2 "viable,fertile" FBgn0261585 CG42695 - http://flybase.org/reports/FBgn0261585 protein_coding_gene - - - CG42695 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005148 l(2)DTS19 lethal (2) DTS19 http://flybase.org/reports/FBgn0005148 - gene - - - "DTS-L19, l(2)DTS19" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0003675 Tcp Third cold paralytic http://flybase.org/reports/FBgn0003675 - gene - - - "TCP, Tcp" - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0036663 CG9674 - http://flybase.org/reports/FBgn0036663 protein_coding_gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR009051 glutamate synthase (NADH) activity ; GO:0016040 | inferred from electronic annotation with InterPro:IPR012220 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012220 FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR012220 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR012220 glutamate synthase activity ; GO:0015930 | inferred from biological aspect of ancestor with PANTHER:PTN000234342 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002489, InterPro:IPR002932, InterPro:IPR006005, InterPro:IPR006982, InterPro:IPR012220, InterPro:IPR023753 glutamate biosynthetic process ; GO:0006537 | inferred from biological aspect of ancestor with PANTHER:PTN000234342 ammonia assimilation cycle ; GO:0019676 | inferred from biological aspect of ancestor with PANTHER:PTN000234342" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000234102 CG9674 "IPR002489:Glutamate synthase, alpha subunit, C-terminal, IPR002932:Glutamate synthase domain, IPR006005:Glutamate synthase, NADH/NADPH, small subunit 1, IPR006982:Glutamate synthase, central-N, IPR009051:Alpha-helical ferredoxin, IPR012220:Glutamate synthase, eukaryotic, IPR013785:Aldolase-type TIM barrel, IPR023753:FAD/NAD(P)-binding domain, IPR017932:Glutamine amidotransferase type 2 domain, IPR029055:Nucleophile aminohydrolases, N-terminal, IPR028261:Dihydroprymidine dehydrogenase domain II" CG9674 11-Aug-17 DroID_v2017_08 Drer\dpydb Scer\GLT1 Cele\W07E11.1 - Mmus\Dpyd Hsap\DPYD "viable,fertile" FBgn0020802 ms(3)D120 ms(3)D120 http://flybase.org/reports/FBgn0020802 - gene - - - "3-D120, ms(3)D120" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive,male sterile" FBgn0020535 l(2)k06003 lethal (2) k06003 http://flybase.org/reports/FBgn0020535 - gene - - - "l(2)06003, l(2)k06003" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024187 syd sunday driver http://flybase.org/reports/FBgn0024187 FBgn0035826 protein_coding_gene kinesin binding ; GO:0019894 | inferred from physical interaction with Klc receptor signaling complex scaffold activity ; GO:0030159 | inferred from biological aspect of ancestor with PANTHER:PTN001015989 JUN kinase binding ; GO:0008432 | inferred from biological aspect of ancestor with PANTHER:PTN000356517 MAP-kinase scaffold activity ; GO:0005078 | inferred from sequence or structural similarity with UniProtKB:Q9ESN9 MAP-kinase scaffold activity ; GO:0005078 | inferred from biological aspect of ancestor with PANTHER:PTN001015989 axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from expression pattern vesicle-mediated transport ; GO:0016192 | inferred from biological aspect of ancestor with PANTHER:PTN001015989 activation of JUN kinase activity ; GO:0007257 | inferred from biological aspect of ancestor with PANTHER:PTN000356517 regulation of JNK cascade ; GO:0046328 | inferred from sequence or structural similarity with UniProtKB:Q9ESN9 membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:14524 inferred from sequence or structural similarity with HGNC:6884 Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity with UniProtKB:Q9ESN9 trans-Golgi network transport vesicle ; GO:0030140 | inferred from direct assay "CG8110, JIP-3, syd, jip3, Syd" "IPR019143:JNK/Rab-associated protein-1, N-terminal, IPR011044:Quinoprotein amine dehydrogenase, beta chain-like, IPR011990:Tetratricopeptide-like helical domain, IPR034743:RH1 domain, IPR034744:RH2 domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032486:JNK-interacting protein, leucine zipper II" CG8110 11-Aug-17 DroID_v2017_08 "Drer\spag9a, Drer\spag9b, Drer\si:dkey-17m8.1, Drer\mapk8ip3" Scer\SEC3 Cele\unc-16 Xtro\spag9 "Mmus\Mapk8ip3, Mmus\Spag9" "Hsap\MAPK8IP3, Hsap\SPAG9" "viable,fertile,neuroanatomy defective,hypoactive,recessive,behavior defective,lethal - all die before end of larval stage,some die during larval stage" "NMJ bouton,larva,abdominal segmental nerve,synaptic vesicle" FBgn0015976 l(2)PC4-B lethal (2) PC4-B http://flybase.org/reports/FBgn0015976 - gene - - - l(2)PC4-B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015404 l(1)11BEa lethal (1) 11BEa http://flybase.org/reports/FBgn0015404 - gene - - - l(1)11BEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026350 Su(da[lyh])22C1 Su(da[lyh])22C1 http://flybase.org/reports/FBgn0026350 - gene - - - "Su(da[lyh]), Su(da[lyh])22C1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053467 CG33467 - http://flybase.org/reports/FBgn0053467 protein_coding_gene - - - CG33467 IPR010512:Protein of unknown function DUF1091 CG33467 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035482 CG14985 - http://flybase.org/reports/FBgn0035482 protein_coding_gene - - - CG14985 "IPR007330:MIT, IPR032341:MIT, C-terminal phospholipase D-like domain" CG14985 11-Aug-17 DroID_v2017_08 Drer\mitd1 - Cele\Y66D12A.10 Xtro\mitd1 Mmus\Mitd1 Hsap\MITD1 viable FBgn0083074 ms(3)o33 ms(3)o33 http://flybase.org/reports/FBgn0083074 gene - - - ms(3)o33 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002190 l(3)63Ba lethal (3) 63Ba http://flybase.org/reports/FBgn0002190 - gene - - - l(3)63Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0050457 CG30457 - http://flybase.org/reports/FBgn0050457 protein_coding_gene - - - "CG30457, CG17288, CG30457-PA" IPR004011:GYR motif CG30457 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC06661 E 0.555847597 -0.123067244 -1.306870128 1.664267094 -0.570767548 0.434728687 FBgn0069140 mcl(3)Z5502 mcl(3)Z5502 http://flybase.org/reports/FBgn0069140 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z5502 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0065931 l(2)SH0134 lethal (2) SH0134 http://flybase.org/reports/FBgn0065931 gene - - - "l(2)SH0134, l(2)SH2 0134" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259268 C375 - http://flybase.org/reports/FBgn0259268 gene - - - C375 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing vein,chaeta" FBgn0039827 CG1544 - http://flybase.org/reports/FBgn0039827 protein_coding_gene thiamine pyrophosphate binding ; GO:0030976 | inferred from electronic annotation with InterPro:IPR011603 oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591 | inferred from biological aspect of ancestor with PANTHER:PTN000568211 oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591 | inferred from sequence or structural similarity with UniProtKB:P81895 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000568211 generation of precursor metabolites and energy ; GO:0006091 | inferred from sequence or structural similarity with UniProtKB:P81895 mitochondrial membrane ; GO:0031966 | inferred from sequence or structural similarity with UniProtKB:P81895 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000568260 oxoglutarate dehydrogenase complex ; GO:0045252 | inferred from biological aspect of ancestor with PANTHER:PTN000568211 CG1544 "IPR001017:Dehydrogenase, E1 component, IPR005475:Transketolase-like, pyrimidine-binding domain, IPR011603:2-oxoglutarate dehydrogenase E1 component, IPR029061:Thiamin diphosphate-binding fold, IPR031717:Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal" CG1544 11-Aug-17 DroID_v2017_08 "Drer\dhtkd1, Drer\ogdhb, Drer\ogdha, Drer\ogdhl" Scer\KGD1 "Cele\ZK836.2, Cele\ogdh-1" "Xtro\ogdh, Xtro\ogdhl, Xtro\dhtkd1" "Mmus\Dhtkd1, Mmus\Ogdh, Mmus\Ogdhl" "Hsap\OGDH, Hsap\DHTKD1, Hsap\OGDHL" "viable,fertile" DRSC15036 K 0.161373115 -0.28246628 0.667221183 0.795827835 -1.710257735 -0.121167206 FBgn0035357 MEP-1 MEP-1 http://flybase.org/reports/FBgn0035357 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 nucleosome-dependent ATPase activity ; GO:0070615 | contributes_to inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Mi-2 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay NuRD complex ; GO:0016581 | inferred from physical interaction with Mi-2 polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "clone 1.37, anon-WO0118547.584, anon-EST:Liang-1.37, CG1244, MEP-1, dMEP-1, MEP1, Q0E8J0_DROME" IPR013087:Zinc finger C2H2-type CG1244 11-Aug-17 DroID_v2017_08 "Drer\znf827, Drer\znf513, Drer\pogza, Drer\znf280d" - Cele\mep-1 - "Mmus\Zfp513, Mmus\Zfp592, Mmus\Zfp532, Mmus\Zfp687, Mmus\Zfp827" "Hsap\ZNF513, Hsap\ZNF827" "lethal,recessive" DRSC29362 IK 4.475491095 -2.329759529 1.000530012 -0.046388653 1.722342271 1.761416358 FBgn0085288 CG34259 - http://flybase.org/reports/FBgn0085288 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34259 - CG34259 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036294 CG10654 - http://flybase.org/reports/FBgn0036294 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG10654 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG10654 11-Aug-17 DroID_v2017_08 "Drer\LOC100534979, Drer\znf1174, Drer\si: zfos-932h1.3, Drer\si:dkeyp-121d2.7" Scer\AZF1 "Cele\Y5F2A.4, Cele\che-1, Cele\pag-3, Cele\pat-9, Cele\fezf-1, Cele\M03D4.4, Cele\blmp-1" - Mmus\Zfp324 "Hsap\ZNF324B, Hsap\MECOM, Hsap\ZNF324" viable FBgn0259284 EP-322 - http://flybase.org/reports/FBgn0259284 gene - - - EP-322 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,chaeta" FBgn0001914 l(2)25Ba lethal (2) 25Ba http://flybase.org/reports/FBgn0001914 - gene - - - "jf10, l(2)jf10, l(2)25Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035097 CG13405 - http://flybase.org/reports/FBgn0035097 protein_coding_gene - - - "BcDNA:AT11049, CG13405" IPR023324:BH2638-like domain CG13405 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267847 T:CRAT-PTS1 PTS1 peroxisomal matrix targeting signal of CRAT http://flybase.org/reports/FBgn0267847 engineered_tag - - - T:CRAT-PTS1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027960 l(3)S147006 lethal (3) S147006 http://flybase.org/reports/FBgn0027960 gene - - - "1470/06, l(3)S147006" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030221 Rab9Db Rab at 9Db http://flybase.org/reports/FBgn0030221 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 "Rab9Db, CG9807" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9807 11-Aug-17 DroID_v2017_08 "Drer\rab1bb, Drer\si:dkey-16l2.16, Drer\rab43, Drer\rabl6a, Drer\rab1aa, Drer\zgc:101559, Drer\rab1ba, Drer\rab1ab, Drer\rab33ba, Drer\zgc:171927, Drer\rab35b, Drer\rab19, Drer\rab33a, Drer\rabl6b, Drer\rab35a" "Scer\TEM1, Scer\YPT1, Scer\YPT10" "Cele\rab-35, Cele\rab-28" "Xtro\rab28, Xtro\rab1a, Xtro\rab33a, Xtro\rab19, Xtro\rab33b, Xtro\rabl6" "Mmus\Rab43, Mmus\Rab28, Mmus\Rab1b, Mmus\Rab33a, Mmus\Rab33b, Mmus\Rabl3, Mmus\Rab19, Mmus\Rab35, Mmus\Rabl6, Mmus\Rab1a" "Hsap\RAB33B, Hsap\RAB43, Hsap\RAB28, Hsap\RAB19, Hsap\RAB1B, Hsap\RABL3, Hsap\RABL6, Hsap\RAB1A, Hsap\RAB35, Hsap\RAB33A" FBgn0041764 aos::fng argos::fng http://flybase.org/reports/FBgn0041764 engineered_fusion_gene - - - "argos::fng, aos::fng" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye FBgn0034807 CG9897 - http://flybase.org/reports/FBgn0034807 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SPH195, CG9897" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG9897 11-Aug-17 DroID_v2017_08 "Drer\st14b, Drer\prss56, Drer\si:ch211-165b19.9" - - - "Mmus\Prss56, Mmus\Egfbp2, Mmus\Klk7, Mmus\Klk1b3, Mmus\Klk1, Mmus\Klk1b8, Mmus\Klk14, Mmus\Klk13" "Hsap\PRSS56, Hsap\KLK8" "viable,mating behavior defective,female limited" FBgn0001838 l(1)ts982 lethal (1) ts982 http://flybase.org/reports/FBgn0001838 - gene - - - l(1)ts982 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0004761 l(3)89Cb lethal (3) 89Cb http://flybase.org/reports/FBgn0004761 - gene - - - l(3)89Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000637 fbr fine bristles http://flybase.org/reports/FBgn0000637 - gene - - - "fb, fbr" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible macrochaeta FBgn0000785 fs(1)A1578 female sterile (1) A1578 http://flybase.org/reports/FBgn0000785 - gene - - - "fs(1)1578, fs(1)A1578" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,non-rescuable maternal effect" egg FBgn0036426 CG9592 - http://flybase.org/reports/FBgn0036426 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN001592797 - extrinsic component of endoplasmic reticulum membrane ; GO:0042406 | inferred from biological aspect of ancestor with PANTHER:PTN001592797 CG9592 - CG9592 11-Aug-17 DroID_v2017_08 Drer\ccdc115 Scer\VMA22 - - Mmus\Ccdc115 Hsap\CCDC115 "viable,fertile" DRSC11078 I 2.214554638 -0.524720924 0.550581523 1.165977991 -0.079879246 -0.456965957 FBgn0016756 Usp47 Ubiquitin specific protease 47 http://flybase.org/reports/FBgn0016756 "FBgn0013225, FBgn0047212" protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype inferred from genetic interaction with ttk protein stabilization ; GO:0050821 | inferred from direct assay regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000607280 protein deubiquitination ; GO:0016579 | inferred from direct assay regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from genetic interaction with slbo base-excision repair ; GO:0006284 | inferred from biological aspect of ancestor with PANTHER:PTN000607280 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Ubp64, UBP, D-UBP-64E, D-Ubp-64E, E(var)3-64E, E-var(3)64E, E(var)1, CG5486, BcDNA:LD12764, ubp64, Ubp64E, ubp64E, dUbp64, dUSP47, Usp47, Q24574, usp47, Upd64E, UBP64E" "IPR018200:Ubiquitin specific protease, conserved site, IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889:Ubiquitin specific protease domain" CG5486 11-Aug-17 DroID_v2017_08 "Drer\usp47, Drer\usp25, Drer\usp28" "Scer\UBP3, Scer\UBP15" "Cele\K02C4.3, Cele\T05H10.1" "Xtro\usp25, Xtro\usp48, Xtro\usp28, Xtro\usp47" "Mmus\Usp25, Mmus\Usp28, Mmus\Usp47, Mmus\Usp18" "Hsap\USP18, Hsap\USP47, Hsap\USP28, Hsap\USP41, Hsap\USP25" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "visible,viable,enhancer of variegation,dominant,fertile,lethal,short lived,locomotor behavior defective" "eye,ommatidium | adult stage,interommatidial bristle,eye disc | pupal stage,cone cell | pupal stage,photoreceptor cell | pupal stage,ommatidium,supernumerary,eye disc,cone cell,photoreceptor cell,testis,medial triple row,germline cell,male,wing" DRSC11313 K 1.281316321 0.412417825 0.074395258 0.357223098 -1.883589115 -1.576330818 FBgn0261060 Sfp93F Seminal fluid protein 93F http://flybase.org/reports/FBgn0261060 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay Sfp93F - CG42608 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062616 Mod(var)1250 Mod(var)1250 http://flybase.org/reports/FBgn0062616 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1250, Mod(var)1250" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,viable" FBgn0266510 s-460 - http://flybase.org/reports/FBgn0266510 gene - - - s-460 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026257 cav caravaggio http://flybase.org/reports/FBgn0026257 FBgn0020360 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR026299 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:B7Z0L8 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VR09 telomeric DNA binding ; GO:0042162 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P05205 telomere capping ; GO:0016233 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred from expression pattern "mitochondrial small ribosomal subunit ; GO:0005763 | inferred from electronic annotation with InterPro:IPR026299 telomere cap complex ; GO:0000782 | inferred from direct assay chromosome, telomeric region ; GO:0000781 | inferred from direct assay nuclear chromosome, telomeric region ; GO:0000784 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay" "HOAP, anon1G5, p55, anon fe 1G5, Hoap, Anon1G5, 1G5, anon-EST:fe1G5, CG6219, cav, Caravaggio, hoap" IPR026299:Mitochondrial 28S ribosomal protein S31 CG6219 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male limited,maternal effect,partially lethal - majority die,dominant,recessive,neuroanatomy defective,suppressor of variegation,partially,mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,body color defective,fertile" "neuroblast,mitotic metaphase,metaphase & condensed nuclear chromosome,chromosome, telomeric region,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0082357 HM210 HM210 http://flybase.org/reports/FBgn0082357 gene - - - HM210 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263553 mir-4913 mir-4913 stem loop http://flybase.org/reports/FBgn0263553 miRNA_gene - - - "mir-4913, dme-mir-4913, CR43538" - CR43538 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037619 CG8159 - http://flybase.org/reports/FBgn0037619 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 CG8159 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8159 11-Aug-17 DroID_v2017_08 "Drer\znf341, Drer\znf770, Drer\znf1178, Drer\bcl6ab" Scer\AZF1 "Cele\klf-3, Cele\blmp-1, Cele\Y37F4.6, Cele\M03D4.4, Cele\eor-1" - "Mmus\Zfp445, Mmus\Zfp810, Mmus\Zfp24, Mmus\Zfp341, Mmus\Zfp369, Mmus\Zscan5b, Mmus\Zfp110" "Hsap\ZNF784, Hsap\ZNF281, Hsap\ZNF221, Hsap\ZNF560, Hsap\ZNF341, Hsap\ZNF8, Hsap\ZNF284" viable FBgn0026434 En(tkv*)3-3 En(tkv*)3-3 http://flybase.org/reports/FBgn0026434 - gene - - - "En(Tkv*)3-3, En(tkv*)3-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038763 PIG-L Phosphatidylinositol glycan anchor biosynthesis class L http://flybase.org/reports/FBgn0038763 protein_coding_gene N-acetylglucosaminylphosphatidylinositol deacetylase activity ; GO:0000225 | inferred from sequence or structural similarity with RGD:620437 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with RGD:620437 cellular_component ; GO:0005575 | no biological data available "PIG-L, CG4433" "IPR003737:N-acetylglucosaminyl phosphatidylinositol deacetylase-related, IPR024078:Putative deacetylase LmbE-like domain" CG4433 11-Aug-17 DroID_v2017_08 Drer\pigl Scer\GPI12 Cele\Y52B11C.1 Xtro\pigl Mmus\Pigl Hsap\PIGL viable DRSC15577 K 0.232038324 0.205327486 -0.119173187 0.460269568 2.29121056 0.4943438 FBgn0037415 Osi8 Osiris 8 http://flybase.org/reports/FBgn0037415 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi8, CG15591" IPR012464:Protein of unknown function DUF1676 CG15591 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065144 l(3)SH093 lethal (3) SH093 http://flybase.org/reports/FBgn0065144 gene - - - "l(3)SH093, l(2)SH3 093" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031501 CG17261 - http://flybase.org/reports/FBgn0031501 protein_coding_gene - - - CG17261 - CG17261 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040814 CG14113 - http://flybase.org/reports/FBgn0040814 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14113 - CG14113 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0040327 EY3-4 EY3-4 http://flybase.org/reports/FBgn0040327 gene - - - EY3-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043068 MstProx::Tl MstProx::Tl http://flybase.org/reports/FBgn0043068 engineered_fusion_gene - - - MstProx::Tl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040467 Dlip1 Dorsal interacting protein 1 http://flybase.org/reports/FBgn0040467 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 lateral inhibition ; GO:0046331 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "dip1, CG15367, Dlip1, Dip1, DIP1" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG15367 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,mesothoracic tergum" FBgn0265670 CG44477 - http://flybase.org/reports/FBgn0265670 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44477 - CG44477 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265580 CR44407 - http://flybase.org/reports/FBgn0265580 non_protein_coding_gene - - - CR44407 - CR44407 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029899 CG14438 - http://flybase.org/reports/FBgn0029899 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG14438 IPR013087:Zinc finger C2H2-type CG14438 11-Aug-17 DroID_v2017_08 "Drer\im:7147486, Drer\znf142" Scer\RME1 - - "Mmus\Zfp574, Mmus\Zfp236, Mmus\Zfp142" "Hsap\ZNF572, Hsap\ZNF574, Hsap\ZNF142" "viable,fertile,neuroanatomy defective,female sterile" neurite | pharate adult stage FBgn0015414 l(1)15ACa lethal (1) 15ACa http://flybase.org/reports/FBgn0015414 - gene - - - l(1)15ACa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263466 snoRNA:lola-a - http://flybase.org/reports/FBgn0263466 snoRNA_gene - - - snoRNA:lola-a - CR43581 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040343 CG3713 - http://flybase.org/reports/FBgn0040343 protein_coding_gene - - - "EG:BACR7A4.2, BcDNA:GH13231, CG3713" - CG3713 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260294 GSd079 - http://flybase.org/reports/FBgn0260294 gene - - - GSd079 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0037310 Tim17b1 Tim17b1 http://flybase.org/reports/FBgn0037310 protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000050380 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O60830 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O60830 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:O60830 "CG1158, BcDNA:AT16284, Tim17b1" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG1158 11-Aug-17 DroID_v2017_08 "Drer\timm17a, Drer\timm17b" Scer\TIM17 "Cele\E04A4.5, Cele\D2096.1" Xtro\timm17a "Mmus\Timm17b, Mmus\Timm17a" "Hsap\TIMM17A, Hsap\TIMM17B" viable FBgn0040113 l(2)AR-49 lethal (2) AR-49 http://flybase.org/reports/FBgn0040113 gene - - - l(2)AR-49 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262541 CG43095 - http://flybase.org/reports/FBgn0262541 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43095 - CG43095 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004181 Ebp Ejaculatory bulb protein http://flybase.org/reports/FBgn0004181 "FBgn0028493, FBgn0044740" protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern post-mating behavior ; GO:0045297 | inferred from expression pattern mating plug formation ; GO:0042628 | traceable author statement extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG2668, PEB-me, PEB, P38, peb, BcDNA:GH06048, anon-WO0140519.140, Peb, Ebp, PEBme" - CG2668 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033301 CG12780 - http://flybase.org/reports/FBgn0033301 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with GNBP3 defense response to virus ; GO:0051607 | inferred from expression pattern detection of biotic stimulus ; GO:0009595 | inferred from sequence or structural similarity with GNBP3 cell surface ; GO:0009986 | inferred from sequence or structural similarity with GNBP3 "GNBP-like, CG12780" "IPR031756:Beta-1,3-glucan-binding protein, N-terminal" CG12780 11-Aug-17 DroID_v2017_08 - - Cele\Y53H1B.4 - - - viable FBgn0066375 arap arap http://flybase.org/reports/FBgn0066375 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available arap - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,memory defective" FBgn0262540 CG43094 - http://flybase.org/reports/FBgn0262540 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43094 - CG43094 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261939 robo1::robo3 - http://flybase.org/reports/FBgn0261939 engineered_fusion_gene - - - "robo::robo3, robo1::robo3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266431 CG45061 - http://flybase.org/reports/FBgn0266431 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45061, CG42262, CG32696, CG15245, CG15246" - CG45061 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085704 CG41578 - http://flybase.org/reports/FBgn0085704 protein_coding_gene - - - CG41578 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010026 E(Dl)F14 Enhancer of Delta F14 http://flybase.org/reports/FBgn0010026 - gene - - - E(Dl)F14 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259363 EP-947 - http://flybase.org/reports/FBgn0259363 gene - - - EP-947 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0265892 CR44681 - http://flybase.org/reports/FBgn0265892 non_protein_coding_gene - - - CR44681 - CR44681 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266872 CR45333 - http://flybase.org/reports/FBgn0266872 non_protein_coding_gene - - - CR45333 - CR45333 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023084 fldA flight defective A at 46C http://flybase.org/reports/FBgn0023084 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available fldA - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" "indirect flight muscle,myofibril,mitochondrial membrane,nervous system,giant fiber neuron" FBgn0005137 l(2)39a lethal (2) 39a http://flybase.org/reports/FBgn0005137 - gene - - - l(2)39a - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0042159 CG18836 - http://flybase.org/reports/FBgn0042159 protein_coding_gene - - - CG18836 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002113 l(2)ay lethal (2) ay http://flybase.org/reports/FBgn0002113 - gene - - - l(2)ay - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267184 CR45624 - http://flybase.org/reports/FBgn0267184 non_protein_coding_gene - - - CR45624 - CR45624 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028836 CSN7 COP9 signalosome subunit 7 http://flybase.org/reports/FBgn0028836 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with alien inferred from physical interaction with CSN4 NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from sequence or structural similarity with HGNC:16758 female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from mutant phenotype germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs regulation of cell cycle ; GO:0051726 | inferred from direct assay nuclear periphery ; GO:0034399 | inferred from direct assay COP9 signalosome ; GO:0008180 | inferred from mutant phenotype COP9 signalosome ; GO:0008180 | inferred from direct assay COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity with MGI:MGI:1349388 inferred from sequence or structural similarity with MGI:MGI:1349400 inferred from direct assay inferred from physical interaction with alien inferred from physical interaction with CSN5 inferred from physical interaction with CSN4 "CSN7, csn7, Dch7, CG2038, CSN7b, CH7, Csn7" IPR000717:Proteasome component (PCI) domain CG2038 11-Aug-17 DroID_v2017_08 Drer\cops7a - - Xtro\cops7b "Mmus\Cops7a, Mmus\Cops7b" "Hsap\COPS7B, Hsap\COPS7A" "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell" DRSC06807 K 0.0486661 -0.174383387 -0.62619243 0.156327332 1.168020166 2.699860172 FBgn0016037 mis-b mis-b http://flybase.org/reports/FBgn0016037 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "mis b, mis-b" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060628 l(3)S087106 lethal (3) S087106 http://flybase.org/reports/FBgn0060628 gene - - - "0871/06, l(3)S087106" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0034573 CG3295 - http://flybase.org/reports/FBgn0034573 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000255799 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 GID complex ; GO:0034657 | inferred from biological aspect of ancestor with PANTHER:PTN000255799 CG3295 "IPR024964:CTLH/CRA C-terminal to LisH motif domain, IPR006594:LIS1 homology motif, IPR006595:CTLH, C-terminal LisH motif, IPR013144:CRA domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027711:Rmd5" CG3295 11-Aug-17 DroID_v2017_08 Drer\rmnd5b Scer\RMD5 Cele\T07D1.2 Xtro\rmnd5a "Mmus\Rmnd5b, Mmus\Rmnd5a" "Hsap\RMND5B, Hsap\RMND5A" "viable,body color defective" mesothoracic tergum DRSC04356 EK 1.077589839 -1.086036782 -1.535579799 -0.357837638 2.759762461 0.018978343 FBgn0038819 Cpr92F Cuticular protein 92F http://flybase.org/reports/FBgn0038819 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr92F, CG5494" IPR000618:Insect cuticle protein CG5494 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0016976 stnA stoned A http://flybase.org/reports/FBgn0016976 "FBan0012500, FBgn0003533, FBgn0058306, FBgn0063778" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P21521 inferred from physical interaction with UniProtKB:Q24212 synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | traceable author statement flight behavior ; GO:0007629 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | traceable author statement response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype endocytic vesicle ; GO:0030139 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from genetic interaction with Syt1 inferred from physical interaction with Csp inferred from physical interaction with Syt1 "CG12500, stn, stn-A, STNA, ORF1, l(1)X-3, x-3, X3, X-3, 8P1, X-43, lR9-10, l8P1, 32, 31, 20, CG40306, sesC, l(1)20Bc, l(1)13-20, stnA, CG12473/CG12500, StnA" - CG12500 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult stage " adult thorax

, adult head

, adult abdomen

" "lethal - all die before end of embryonic stage,some die during embryonic stage,uncoordinated,recessive,neurophysiology defective,lethal,behavior defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,neuroanatomy defective,locomotor behavior defective,viable,bang sensitive,jumping defective,paralytic,partially lethal - majority die" "axon terminus,synaptic vesicle,multivesicular body,indirect flight muscle" FBgn0061149 l(3)85Da-2 lethal (3) 85Da-2 http://flybase.org/reports/FBgn0061149 gene - - - l(3)85Da-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002168 l(2)Sp10 lethal (2) Sp10 http://flybase.org/reports/FBgn0002168 - gene - - - l(2)Sp10 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040558 CG14361 - http://flybase.org/reports/FBgn0040558 protein_coding_gene - - - CG14361 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085811 CR41598 - http://flybase.org/reports/FBgn0085811 non_protein_coding_gene - - - CR41598 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038866 CG5810 - http://flybase.org/reports/FBgn0038866 protein_coding_gene - - - "CT18214, CG5810" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG5810 11-Aug-17 DroID_v2017_08 - - - - - Hsap\LGR6 viable FBgn0262849 CR43213 - http://flybase.org/reports/FBgn0262849 pseudogene_attribute - - - "CR43213, noncoding_23159, noncoding_23161" - CR43213 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085537 CG40928 - http://flybase.org/reports/FBgn0085537 protein_coding_gene - - - CG40928 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030894 Mvb12 Multivesicular body subunit 12 http://flybase.org/reports/FBgn0030894 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000003438 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred by curator from GO:0000813 ESCRT I complex ; GO:0000813 | inferred from sequence or structural similarity with SGD:S000003438 ESCRT I complex ; GO:0000813 | inferred from direct assay "Mvb12, CG7192" "IPR018798:Multivesicular body subunit 12, IPR023340:UMA domain, IPR023341:MABP domain" CG7192 11-Aug-17 DroID_v2017_08 "Drer\mvb12bb, Drer\mvb12a, Drer\mvb12ba" - Cele\mvb-12 "Xtro\mvb12a, Xtro\mvb12b" "Mmus\Mvb12a, Mmus\Mvb12b" "Hsap\MVB12B, Hsap\MVB12A" "viable,fertile" FBgn0263859 P95 P95 http://flybase.org/reports/FBgn0263859 gene - memory ; GO:0007613 | inferred from mutant phenotype - P95 - - 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,recessive" FBgn0051813 CG31813 - http://flybase.org/reports/FBgn0051813 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BG:DS08249.4, BcDNA:RE62259, CG31813" - CG31813 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001734 l(1)HM2 lethal (1) HM2 http://flybase.org/reports/FBgn0001734 - gene - - - l(1)HM2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive" FBgn0065137 l(3)SH115 lethal (3) SH115 http://flybase.org/reports/FBgn0065137 gene - - - "l(3)SH115, l(2)SH3 115" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039611 CG14528 - http://flybase.org/reports/FBgn0039611 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG14528 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG14528 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\mmel1, Drer\phex, Drer\ece2b" - "Cele\nep-8, Cele\nep-24, Cele\nep-6, Cele\nep-13, Cele\nep-12, Cele\nep-23, Cele\nep-26, Cele\nep-17, Cele\nep-3, Cele\nep-10, Cele\nep-7, Cele\nep-21, Cele\nep-5, Cele\nep-19, Cele\nep-9, Cele\nep-2, Cele\nep-20, Cele\nep-18, Cele\nep-16, Cele\maea-1, Cele\nep-22" "Xtro\ece1, Xtro\mmel1, Xtro\ecel1, Xtro\ece2" "Mmus\Ece2, Mmus\Mme, Mmus\Kel, Mmus\Phex, Mmus\Ecel1, Mmus\Mmel1, Mmus\Ece1" "Hsap\MME, Hsap\KEL, Hsap\ECE1, Hsap\ECEL1, Hsap\MMEL1, Hsap\ECE2, Hsap\PHEX" FBgn0061154 l(2)B73 lethal (2) B73 http://flybase.org/reports/FBgn0061154 gene - - - "B73, l(2)B73" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051755 SoYb Sister of Yb http://flybase.org/reports/FBgn0051755 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 "negative regulation of transposition, RNA-mediated ; GO:0010526 | inferred from genetic interaction with BoYb germ-line stem cell division ; GO:0042078 | inferred from biological aspect of ancestor with PANTHER:PTN001476977" Yb body ; GO:0070725 | inferred from direct assay "CG5831, CG31755, SoYb" "IPR002999:Tudor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR011545:DEAD/DEAH box helicase domain" CG31755 11-Aug-17 DroID_v2017_08 "Drer\tdrd12, Drer\ddx21, Drer\ddx59, Drer\ddx5, Drer\LOC556764" "Scer\DBP2, Scer\DBP3" - "Xtro\ddx5, Xtro\ddx59, Xtro\ddx21, Xtro\gpr149, Xtro\ddx17" "Mmus\Ddx5, Mmus\Ddx59, Mmus\Ddx17, Mmus\Ddx50, Mmus\Tdrd12, Mmus\Gpr149, Mmus\Ddx21" "Hsap\DDX59, Hsap\TDRD12, Hsap\DDX17, Hsap\DDX50, Hsap\GPR149, Hsap\DDX5, Hsap\DDX21" FBgn0047334 BG642312 BG642312 http://flybase.org/reports/FBgn0047334 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG33943, BG642312(4h1), pncr010:3L, CR33943, BcDNA:AT24650, BG642312, 4h1" - CG33943 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025560 anon-66Fa anon-66Fa http://flybase.org/reports/FBgn0025560 - gene - - - anon-66Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083972 CG34136 - http://flybase.org/reports/FBgn0083972 protein_coding_gene - - - CG34136 - CG34136 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000842 fs(1)M29 female sterile (1) M29 http://flybase.org/reports/FBgn0000842 - gene - - - "fs(1)151, fs(1)M29" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0033723 CG13155 - http://flybase.org/reports/FBgn0033723 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13155 - CG13155 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0030230 Rph Rabphilin http://flybase.org/reports/FBgn0030230 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 calcium-dependent phospholipid binding ; GO:0005544 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab27 calcium-dependent phospholipid binding ; GO:0005544 | inferred from sequence or structural similarity with RGD:620073 regulation of exocytosis ; GO:0017157 | inferred from electronic annotation with InterPro:IPR030538 vesicle-mediated transport ; GO:0016192 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity intracellular protein transport ; GO:0006886 | inferred from sequence or structural similarity with RGD:620073 secretory granule ; GO:0030141 | inferred from sequence or structural similarity with RGD:620073 integral component of membrane ; GO:0016021 | inferred from sequence model synaptic vesicle membrane ; GO:0030672 | inferred from sequence or structural similarity with RGD:620073 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 synaptic vesicle ; GO:0008021 | non-traceable author statement "CG11556, Rph" "IPR000008:C2 domain, IPR001565:Synaptotagmin, IPR010911:Rab-binding domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR017455:Zinc finger, FYVE-related, IPR030541:Rabphilin-1, IPR030538:Rab effector Noc2, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11556 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-93n13.3, Drer\doc2d, Drer\rph3ab, Drer\rph3aa, Drer\doc2b" - Cele\rbf-1 "Xtro\sytl4, Xtro\rph3a, Xtro\rph3al" "Mmus\Doc2g, Mmus\Sytl3, Mmus\Doc2a, Mmus\Doc2b, Mmus\Rph3al, Mmus\Rph3a" "Hsap\RPH3A, Hsap\RPH3AL, Hsap\DOC2B, Hsap\DOC2A, Hsap\SYTL3" FBgn0002337 l(3)87Bf lethal (3) 87Bf http://flybase.org/reports/FBgn0002337 - gene - - - "1418/03, ck18, l(3)ck18, l(3)87Bf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive" FBgn0035642 CG18586 - http://flybase.org/reports/FBgn0035642 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG18586 "IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase" CG18586 11-Aug-17 DroID_v2017_08 Drer\acsf3 Scer\PCS60 "Cele\C32E8.6, Cele\mec-18, Cele\acs-10, Cele\acs-9" Xtro\acsf3 "Mmus\Acsf3, Mmus\Acss2" "Hsap\ACSF3, Hsap\ACSS2" viable FBgn0263613 CR43622 - http://flybase.org/reports/FBgn0263613 non_protein_coding_gene - - - CR43622 - CR43622 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085656 CG41495 - http://flybase.org/reports/FBgn0085656 protein_coding_gene - - - CG41495 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041104 neuro-d4 neuro-d4 http://flybase.org/reports/FBgn0041104 gene - - - neuro-d4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031620 CG11929 - http://flybase.org/reports/FBgn0031620 protein_coding_gene - - - CG11929 - CG11929 11-Aug-17 DroID_v2017_08 - - - Xtro\c3orf49 - - viable FBgn0000447 Dhod Dihydroorotate dehydrogenase http://flybase.org/reports/FBgn0000447 FBgn0024585 protein_coding_gene dihydroorotate dehydrogenase activity ; GO:0004152 | inferred from direct assay dihydroorotate dehydrogenase activity ; GO:0004152 | inferred from sequence or structural similarity with UniProtKB:Q02127 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001295, InterPro:IPR005719, InterPro:IPR005720 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from sequence or structural similarity with UniProtKB:Q02127" mitochondrial intermembrane space ; GO:0005758 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q02127 "dhod, DHODH, DHOD, l(3)s3512, CG9741, Dhod" "IPR001295:Dihydroorotate dehydrogenase, conserved site, IPR005719:Dihydroorotate dehydrogenase, class 2, IPR013785:Aldolase-type TIM barrel, IPR005720:Dihydroorotate dehydrogenase domain" CG9741 11-Aug-17 DroID_v2017_08 Drer\dhodh Scer\URA1 Cele\dhod-1 Xtro\dhodh Mmus\Dhodh Hsap\DHODH embryonic stage -- adult stage spermatogenesis && adult stage spermatid

"lethal,recessive,visible,viable,female fertile,wild-type,female sterile" "eye,arista,wing,wing hair" DRSC16647 K 0.139349397 0.006712879 0.262450955 -0.189907611 1.571456147 0.056783255 FBgn0034956 CG4324 - http://flybase.org/reports/FBgn0034956 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 CG4324 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG4324 11-Aug-17 DroID_v2017_08 "Drer\sv2c, Drer\svopb, Drer\sv2bb, Drer\slc22a6l, Drer\sv2a, Drer\slc22a7a, Drer\svopa, Drer\si:dkey-166k12.1, Drer\slc22a7b.1, Drer\slc22a16, Drer\svopl, Drer\zgc:153639" "Scer\HXT2, Scer\PHO84" "Cele\svop-1, Cele\T22F7.1, Cele\Y82E9BR.16, Cele\oct-1" "Xtro\sv2b, Xtro\svop, Xtro\slc22a6, Xtro\svopl, Xtro\sv2a, Xtro\slc22a5, Xtro\sv2c" "Mmus\Slc22a8, Mmus\Slc22a7, Mmus\Slc22a4, Mmus\Svop, Mmus\Slc22a20, Mmus\Slc22a13, Mmus\Sv2a, Mmus\Slc22a21, Mmus\Slc22a16, Mmus\Svopl, Mmus\Sv2c, Mmus\Slc22a12, Mmus\Sv2b, Mmus\Slc22a6, Mmus\Slc22a5" "Hsap\SVOPL, Hsap\SLC22A4, Hsap\SLC22A20, Hsap\SV2B, Hsap\SLC22A13, Hsap\SLC22A6, Hsap\SLC22A12, Hsap\SV2A, Hsap\SLC22A5, Hsap\SLC22A16, Hsap\SVOP, Hsap\SLC22A8, Hsap\SV2C, Hsap\SLC22A7" viable FBgn0033195 CG1360 - http://flybase.org/reports/FBgn0033195 protein_coding_gene - - - CG1360 - CG1360 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0039601 CG1523 - http://flybase.org/reports/FBgn0039601 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG1523 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG1523 11-Aug-17 DroID_v2017_08 Drer\wdr32 - - Xtro\dcaf10 Mmus\Dcaf10 Hsap\DCAF10 "viable,visible" "embryonic/larval salivary gland,chaeta,supernumerary" DRSC15033 K 0.665839094 0.839717609 0.059182283 0.363573151 0.456537576 1.560785225 FBgn0263626 CR43635 - http://flybase.org/reports/FBgn0263626 non_protein_coding_gene - - - "CR43635, lincRNA.676" - CR43635 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036292 CG10646 - http://flybase.org/reports/FBgn0036292 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0172774.52, CG10646" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG10646 11-Aug-17 DroID_v2017_08 Drer\tssc1 - Cele\eipr-1 Xtro\tssc1 Mmus\Tssc1 Hsap\TSSC1 viable FBgn0243500 l(3)CB02667 - http://flybase.org/reports/FBgn0243500 gene - - - l(3)CB02667 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0021782 l(3)95BCc lethal (3) 95BCc http://flybase.org/reports/FBgn0021782 - gene - - - l(3)95BCc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032190 CG5739 - http://flybase.org/reports/FBgn0032190 protein_coding_gene - - - CG5739 IPR029428:Mapk-regulated corepressor-interacting protein - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264657 panting panting http://flybase.org/reports/FBgn0264657 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - panting - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0261787 brun brunelleschi http://flybase.org/reports/FBgn0261787 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000002815 meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with SGD:S000002815 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000002815 spermatocyte division ; GO:0048137 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay acroblast ; GO:0036063 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000487689 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000002815 Golgi apparatus ; GO:0005794 | inferred from direct assay "CG2478, 38D.28, bru, brun" "IPR013935:TRAPP II complex, Trs120" CG2478 11-Aug-17 DroID_v2017_08 Drer\si:dkey-218f9.10 Scer\TRS120 Cele\trpp-9 Xtro\trappc9 Mmus\Trappc9 Hsap\TRAPPC9 DRSC02706 E -0.976472991 -0.828942793 0.803203958 1.592045874 -0.252788745 0.320603406 FBgn0033170 sPLA2 secretory Phospholipase A2 http://flybase.org/reports/FBgn0033170 protein_coding_gene calcium-dependent phospholipase A2 activity ; GO:0047498 | inferred from direct assay phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090 - "secretory phospholipase A[[2]], CG11124, sPLA[[2]], sPLA2, CG14507" "IPR016090:Phospholipase A2 domain, IPR033113:Phospholipase A2, histidine active site" CG11124 11-Aug-17 DroID_v2017_08 "Drer\LOC101885160, Drer\zgc:123275, Drer\proca1" - "Cele\F36A4.5, Cele\W04G3.12, Cele\F36A4.1, Cele\F47C12.7, Cele\W04G3.7, Cele\F22E5.7, Cele\F36A4.4, Cele\F36A4.3, Cele\W04G3.13, Cele\F47C12.13, Cele\W04G3.10" Xtro\proca1 "Mmus\Proca1, Mmus\Pla2g3" "Hsap\PLA2G3, Hsap\PROCA1" embryonic stage -- adult stage organism

viable FBgn0000906 fs(1)M116 female sterile (1) M116 http://flybase.org/reports/FBgn0000906 - gene - - - fs(1)M116 - - 11-Aug-17 DroID_v2017_08 - - - - - - egg FBgn0039481 Cpr97Eb Cuticular protein 97Eb http://flybase.org/reports/FBgn0039481 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CT33880, Cpr97Eb, CG15884" IPR000618:Insect cuticle protein CG15884 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,viable" wing FBgn0265903 CR44692 - http://flybase.org/reports/FBgn0265903 non_protein_coding_gene - - - CR44692 - CR44692 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039855 CG1638 - http://flybase.org/reports/FBgn0039855 protein_coding_gene - - - "bs31f06.y1, CG1638" "IPR029069:HotDog domain, IPR033120:Hotdog acyl-CoA thioesterase (ACOT)-type domain" CG1638 11-Aug-17 DroID_v2017_08 "Drer\acot11a, Drer\acot12, Drer\acot9.2, Drer\acot7, Drer\acot9.1" - "Cele\T22B7.7, Cele\T07D3.9, Cele\F57F4.1" "Xtro\acot7, Xtro\acot9, Xtro\acot11, Xtro\acot12" "Mmus\Acot12, Mmus\Acot7, Mmus\Acot11, Mmus\Acot10, Mmus\Acot9" "Hsap\ACOT9, Hsap\ACOT11, Hsap\ACOT7, Hsap\ACOT12" "viable,fertile" FBgn0005070 fs(2)OW211 female sterile (2) OW211 http://flybase.org/reports/FBgn0005070 - gene - - - fs(2)OW211 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085760 CR40641 - http://flybase.org/reports/FBgn0085760 rRNA_gene - - - CR40641 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266330 CR44995 - http://flybase.org/reports/FBgn0266330 non_protein_coding_gene - - - CR44995 - CR44995 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267330 KdelR KDEL receptor http://flybase.org/reports/FBgn0267330 protein_coding_gene KDEL sequence binding ; GO:0005046 | inferred from sequence or structural similarity with SGD:S000000136 KDEL sequence binding ; GO:0005046 | inferred from sequence or structural similarity "protein retention in ER lumen ; GO:0006621 | inferred from mutant phenotype retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000133 trans-Golgi network transport vesicle ; GO:0030140 | inferred from sequence or structural similarity endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000000136 endoplasmic reticulum-Golgi intermediate compartment ; GO:0005793 | "KdelR, l(2)31Em, Erd2, dmErd2, l(2)k00311, ERD2, CK00230, CG5183, BEST:CK00230" IPR000133:ER lumen protein retaining receptor CG5183 11-Aug-17 DroID_v2017_08 "Drer\kdelr2b, Drer\kdelr2a, Drer\LOC100537437, Drer\kdelr3" Scer\ERD2 "Cele\C28H8.4, Cele\erd-2" "Xtro\kdelr3, Xtro\kdelr1, Xtro\kdelr2" "Mmus\Kdelr1, Mmus\Kdelr2, Mmus\Kdelr3" "Hsap\KDELR3, Hsap\KDELR2, Hsap\KDELR1" FBgn0031484 CG3165 - http://flybase.org/reports/FBgn0031484 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 - - CG3165 "IPR012337:Ribonuclease H-like domain, IPR013520:Exonuclease, RNase T/DNA polymerase III" CG3165 11-Aug-17 DroID_v2017_08 Drer\si:ch1073-385f13.3 - Cele\W02F12.4 - "Mmus\Trex2, Mmus\Trex1, Mmus\Atrip" "Hsap\TREX2, Hsap\HAUS7, Hsap\TREX1" viable FBgn0010782 l(3)02521 lethal (3) 02521 http://flybase.org/reports/FBgn0010782 - gene - - - l(3)02521 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069399 KH6 KH6 http://flybase.org/reports/FBgn0069399 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available KH6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266179 CR44885 - http://flybase.org/reports/FBgn0266179 non_protein_coding_gene - - - CR44885 - CR44885 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267150 CR45590 - http://flybase.org/reports/FBgn0267150 non_protein_coding_gene - - - CR45590 - CR45590 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019748 l(1)815-9 lethal (1) 815-9 http://flybase.org/reports/FBgn0019748 - gene - - - l(1)815-9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004549 l(4)102CDu lethal (4) 102CDu http://flybase.org/reports/FBgn0004549 - gene - - - "l(4)36, l(4)102CDu" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0051533 CG31533 - http://flybase.org/reports/FBgn0051533 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:LP07046, NEST:bs16a07, BcDNA:AT30147, CG31533" "IPR031949:Domain of unknown function DUF4776, IPR031992:Domain of unknown function DUF4788" CG31533 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000391 cui curvi http://flybase.org/reports/FBgn0000391 - gene - - - cui - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0035557 CG11353 - http://flybase.org/reports/FBgn0035557 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - "anon-WO0172774.162, CG11353" "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG11353 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-39, Cele\oac-7, Cele\oac-31, Cele\oac-14, Cele\oac-32, Cele\oac-9, Cele\oac-50, Cele\oac-3, Cele\oac-20, Cele\oac-53, Cele\oac-46, Cele\oac-6, Cele\nrf-6, Cele\ndg-4, Cele\oac-54, Cele\oac-55, Cele\rhy-1, Cele\oac-5" - Mmus\Oacyl - viable FBgn0001012 fs(3)A3 female sterile (3) A3 http://flybase.org/reports/FBgn0001012 - gene - - - fs(3)A3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0035807 CG7492 - http://flybase.org/reports/FBgn0035807 protein_coding_gene - - - "anon-EST:fe1A11, CG7492, DPLG4" IPR027806:Harbinger transposase-derived nuclease domain CG7492 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000000634, Drer\zgc:162945, Drer\zgc:194221, Drer\zgc:113227, Drer\LOC100005423, Drer\LOC569097" - - Xtro\LOC100127800 Mmus\Harbi1 Hsap\HARBI1 "viable,fertile" FBgn0065539 l(2)SH1067 lethal (2) SH1067 http://flybase.org/reports/FBgn0065539 gene - - - "l(2)SH1067, l(2)SH2 1067" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265149 CR44218 - http://flybase.org/reports/FBgn0265149 non_protein_coding_gene - - - CR44218 - CR44218 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069225 gl(2R)14-22 gl(2R)14-22 http://flybase.org/reports/FBgn0069225 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2R)14-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic abdominal segment,germline clone,maternal effect" FBgn0013232 E(var)183 E(var)183 http://flybase.org/reports/FBgn0013232 - gene - - - E(var)183 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0015008 Actn3 alpha actinin 3 http://flybase.org/reports/FBgn0015008 FBgn0038459 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity - - "CG8953, acta-3, dabp, ORF1, Actn3" IPR001715:Calponin homology domain CG8953 11-Aug-17 DroID_v2017_08 "Drer\specc1lb, Drer\smtnl1, Drer\specc1la, Drer\si:ch211-195o20.7, Drer\smtnb, Drer\smtna, Drer\specc1" - "Cele\T15B12.1, Cele\F26F4.5" "Xtro\smtn, Xtro\specc1l, Xtro\syne2" "Mmus\Smtn, Mmus\Specc1, Mmus\Smtnl2, Mmus\Smtnl1, Mmus\Specc1l" "Hsap\CLMN, Hsap\SMTNL1, Hsap\SMTN, Hsap\SPECC1, Hsap\SPECC1L, Hsap\SMTNL2" viable FBgn0044124 E(rst)B47 E(rst)B47 http://flybase.org/reports/FBgn0044124 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B47, E(rst)B47" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001818 l(1)P3 lethal (1) P3 http://flybase.org/reports/FBgn0001818 - gene - - - l(1)P3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0019730 l(1)XR49 lethal (1) XR49 http://flybase.org/reports/FBgn0019730 - gene - - - l(1)XR49 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010054 JmA Ju myoA http://flybase.org/reports/FBgn0010054 - gene - - - "Jm A, A, JmA" - - 11-Aug-17 DroID_v2017_08 - - - - - - aging defective FBgn0030791 CG9132 - http://flybase.org/reports/FBgn0030791 protein_coding_gene molecular_function ; GO:0003674 | no biological data available endocytosis ; GO:0006897 | inferred from electronic annotation with InterPro:IPR012466 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR012466 "CG32566, CG9132" "IPR012466:NECAP, PHear domain, IPR011993:PH domain-like" CG9132 11-Aug-17 DroID_v2017_08 "Drer\necap2, Drer\necap1" - Cele\Y110A2AR.3 Xtro\necap2 "Mmus\Necap2, Mmus\Necap1" "Hsap\NECAP2, Hsap\NECAP1" "viable,fertile" FBgn0038238 CG14854 - http://flybase.org/reports/FBgn0038238 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14854 - CG14854 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266226 CR44921 - http://flybase.org/reports/FBgn0266226 non_protein_coding_gene - - - CR44921 - CR44921 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003910 tyr1 tyrosine 1 http://flybase.org/reports/FBgn0003910 - gene - - - "tyr-1, tyr1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile,body color defective" "adult,macrochaeta" FBgn0040465 Dlip3 Dorsal interacting protein 3 http://flybase.org/reports/FBgn0040465 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 transcription coactivator activity ; GO:0003713 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with dl transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Dlip3 basal RNA polymerase II transcription machinery binding ; GO:0001099 | inferred from physical interaction with Taf4" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from mutant phenotype antennal development ; GO:0007469 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype inferred from genetic interaction with dl negative regulation of eye photoreceptor cell development ; GO:0042480 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay negative regulation of compound eye photoreceptor development ; GO:0045316 | inferred from mutant phenotype" nuclear chromosome ; GO:0000228 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear body ; GO:0016604 | inferred from direct assay "dip3, CG12767, anon-WO0118547.169, Dlip3, Dip3" "IPR004210:BESS motif, IPR006578:MADF domain" CG12767 11-Aug-17 DroID_v2017_08 Drer\LOC100330838 - - - - - "partially lethal - majority die,some die during embryonic stage,visible,increased cell death,viable,partially lethal - majority live,fertile,immune response defective" "embryonic/larval cuticle | embryonic stage,rhabdomerehs.2sev,ommatidium,eye photoreceptor cell,cone cell,supernumerary,primary pigment cell,eye,crossvein,wing vein,cell non-autonomous,somatic clone,embryonic/larval cuticle" FBgn0260223 CG42497 - http://flybase.org/reports/FBgn0260223 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of dopamine metabolic process ; GO:0042053 | inferred from sequence or structural similarity with MGI:MGI:1930773 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:1930773 "CG42497, Dromel_CG9878_FBtr0071676_tim10_uORF" IPR031833:Protein of unknown function DUF4748 CG42497 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001363 l(1)1Fb lethal (1) 1Fb http://flybase.org/reports/FBgn0001363 - gene - - - l(1)1Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0037661 Ada Adenosine deaminase http://flybase.org/reports/FBgn0037661 protein_coding_gene deaminase activity ; GO:0019239 | inferred from electronic annotation with InterPro:IPR001365 - cellular_component ; GO:0005575 | no biological data available "ADA, CG11994, DrosADA, dADA, Ada, DmADA, ada" "IPR001365:Adenosine/AMP deaminase domain, IPR032466:Metal-dependent hydrolase" CG11994 11-Aug-17 DroID_v2017_08 "Drer\cecr1b, Drer\adal, Drer\rit1, Drer\nras, Drer\si:ch73-116o1.2, Drer\rras2, Drer\zgc:55558, Drer\cecr1a, Drer\ralab, Drer\ada, Drer\ralba, Drer\ralaa, Drer\hrasa, Drer\hrasb, Drer\rras, Drer\kras" Scer\AAH1 "Cele\ral-1, Cele\ras-1, Cele\let-60, Cele\C06G3.5, Cele\C44B7.12" "Xtro\ada.2, Xtro\nras, Xtro\adal, Xtro\ralb, Xtro\rit1, Xtro\ada, Xtro\hras, Xtro\kras, Xtro\rala, Xtro\cecr1" "Mmus\Rras, Mmus\Kras, Mmus\Adal, Mmus\Ada, Mmus\Rala, Mmus\Mras, Mmus\Ralb, Mmus\Hras, Mmus\Rit1, Mmus\Rras2, Mmus\Rit2, Mmus\Nras" "Hsap\RIT1, Hsap\RRAS, Hsap\KRAS, Hsap\RALA, Hsap\RALB, Hsap\NRAS, Hsap\HRAS, Hsap\ADA, Hsap\ADAL, Hsap\MRAS, Hsap\CECR1, Hsap\RRAS2, Hsap\RIT2" viable FBgn0265674 CR44481 - http://flybase.org/reports/FBgn0265674 non_protein_coding_gene - - - "lincRNA.114, CR44481" - CR44481 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051674 CG31674 - http://flybase.org/reports/FBgn0051674 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR006139 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" - "CG9332, CG31674" "IPR006139:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040:NAD(P)-binding domain, IPR029753:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site" CG31674 11-Aug-17 DroID_v2017_08 "Drer\grhprb, Drer\mthfd2, Drer\zgc:136493, Drer\grhpra, Drer\mthfd2l" "Scer\YGL185C, Scer\SER3, Scer\FDH1, Scer\SER33, Scer\YPL113C, Scer\GOR1" Cele\C31C9.2 "Xtro\mthfd2, Xtro\mthfd2l, Xtro\grhpr.2, Xtro\grhpr.1" "Mmus\Mthfd2l, Mmus\Grhpr, Mmus\Mthfd2" "Hsap\GRHPR, Hsap\MTHFD2, Hsap\MTHFD2L, Hsap\PHGDH" "viable,fertile" FBgn0065722 l(2)SH0567 lethal (2) SH0567 http://flybase.org/reports/FBgn0065722 gene - - - "l(2)SH0567, l(2)SH2 0567" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024663 l(2)k06106 lethal (2) k06106 http://flybase.org/reports/FBgn0024663 - gene - - - "61/6, l(2)k06106" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035379 spz5 spatzle 5 http://flybase.org/reports/FBgn0035379 protein_coding_gene growth factor activity ; GO:0008083 | inferred from mutant phenotype Toll binding ; GO:0005121 | inferred from sequence or structural similarity with spz regulation of neuronal synaptic plasticity in response to neurotrophin ; GO:0031637 | inferred from mutant phenotype central nervous system formation ; GO:0021556 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from sequence or structural similarity with spz regulation of cell death ; GO:0010941 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity with spz "CG9972, Spz5, DNT2, spz5, CT28115, NT2, Spz-5" "IPR029034:Cystine-knot cytokine, IPR032104:Spaetzle" CG9972 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell death,fertile,viable,increased cell death,neuroanatomy defective" "intersegmental nerve branch ISNb of A1-7,intersegmental nerve branch ISNd of A1-7,segmental nerve branch SNa of A1-7" FBgn0263079 CG43338 - http://flybase.org/reports/FBgn0263079 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42627, CG43338, CG15165, CG31790" - CG43338 11-Aug-17 DroID_v2017_08 Drer\ccdc170 - Cele\C27D6.1 Xtro\ccdc170 "Mmus\Ccdc170, Mmus\Tex21" Hsap\CCDC170 FBgn0035491 Dpy-30L2 Dpy-30-like 2 http://flybase.org/reports/FBgn0035491 protein_coding_gene histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000599398 chromatin silencing at telomere ; GO:0006348 | inferred from biological aspect of ancestor with PANTHER:PTN000599398 flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype Set1C/COMPASS complex ; GO:0048188 | inferred from biological aspect of ancestor with PANTHER:PTN000599398 "Dpy-30L2, dpy-30L2, CG11591" IPR007858:Dpy-30 motif CG11591 11-Aug-17 DroID_v2017_08 Drer\dpy30 Scer\SDC1 "Cele\F34D10.6, Cele\dpy-30, Cele\R05G6.5" "Xtro\dpy30, Xtro\ak7" Mmus\Dpy30 "Hsap\MEMO1, Hsap\DPY30" "viable,male sterile" spermatozoon FBgn0013560 l(3)ry69 lethal (3) ry69 http://flybase.org/reports/FBgn0013560 - gene - - - "l(3)69, l(3)ry69" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005106 gusE gustatory E http://flybase.org/reports/FBgn0005106 - gene molecular_function ; GO:0003674 | no biological data available larval feeding behavior ; GO:0030536 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gusE - - 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,cold sensitive" FBgn0001978 stc shuttle craft http://flybase.org/reports/FBgn0001978 FBgn0065412 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000967, InterPro:IPR001841 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from biological aspect of ancestor with PANTHER:PTN000270822 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:7803 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000270822 zinc ion binding ; GO:0008270 | inferred from sequence model" "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000270870 regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000270822" nucleus ; GO:0005634 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from direct assay "151662_s_at, CG3647, BcDNA.LD22726, BG:DS04929.4, l(2)35Cb, l35Cb, br33, l(2)br33, l(2)SH1565, Cf4, BcDNA:LD22726, stc, l(2)SH2 1565, LD22726" "IPR000967:Zinc finger, NF-X1-type, IPR001374:R3H domain, IPR001841:Zinc finger, RING-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR034076:Transcriptional repressor NF-X1, R3H domain, IPR034078:Transcription factor NFX1 family" CG3647 11-Aug-17 DroID_v2017_08 "Drer\nfxl1, Drer\si:dkey-10f23.2" Scer\FAP1 Cele\nfx-1 "Xtro\nfx1, Xtro\nfxl1" "Mmus\Nfx1, Mmus\Nfxl1" "Hsap\NFX1, Hsap\NFXL1" " oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

embryonic stage | stage 13-17 " embryonic central nervous system | restricted

, larval brain | restricted

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,maternal effect,viable,short lived,female limited" "embryonic/first instar larval cuticle,maternal effect,denticle belt,intersegmental nerve,abdominal segmental nerve,ventral nerve cord,ventral nerve cord & abdominal segment 4 | maternal effect,ventral nerve cord & abdominal segment 5 | maternal effect,ventral nerve cord & abdominal segment 6 | maternal effect,ventral nerve cord & abdominal segment 7 | maternal effect,ventral nerve cord & abdominal segment 8 | maternal effect,presumptive embryonic/larval central nervous system,central nervous system" FBgn0267937 CR46217 - http://flybase.org/reports/FBgn0267937 non_protein_coding_gene - - - "CR46217, lincRNA.761" - CR46217 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069401 KH4 KH4 http://flybase.org/reports/FBgn0069401 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available KH4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002807 ms(1)20Ab male sterile (1) 20Ab http://flybase.org/reports/FBgn0002807 - gene - - - "ms(1)A, ms(1)20B, ms(1)20Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0029134 Prosbeta5 Proteasome beta5 subunit http://flybase.org/reports/FBgn0029134 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | inferred from sequence or structural similarity with SGD:S000006307 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 neurogenesis ; GO:0022008 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000006307 "cytosol ; GO:0005829 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay proteasome core complex, beta-subunit complex ; GO:0019774 | inferred from sequence or structural similarity with SGD:S000006307" "Prosbeta5, LD08717, dbeta5, CG12323, anon-WO0118547.116, beta-5, Pros b5, PSMB5, Beta-5, beta5" "IPR000243:Peptidase T1A, proteasome beta-subunit, IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR023333:Proteasome B-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG12323 11-Aug-17 DroID_v2017_08 "Drer\psmb5, Drer\si:ch211-14a17.13, Drer\psmb8f, Drer\psmb11b, Drer\psmb8a" Scer\PRE2 Cele\pbs-5 "Xtro\psmb11, Xtro\psmb8, Xtro\psmb5" "Mmus\Psmb5, Mmus\Psmb8, Mmus\Psmb11" "Hsap\PSMB8, Hsap\PSMB11, Hsap\PSMB5" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC07517 IEK -1.584937565 -2.414805182 -2.633388909 -2.372843508 1.509430394 1.131208971 FBgn0265709 CR44516 - http://flybase.org/reports/FBgn0265709 non_protein_coding_gene - - - "incRNA.441, CR44516, lincRNA.441" - CR44516 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259377 EP-429 - http://flybase.org/reports/FBgn0259377 gene - - - EP-429 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0261448 su(rdgA)40 - http://flybase.org/reports/FBgn0261448 gene - - - "su(rdgA)40, su(40)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053703 CG33703 - http://flybase.org/reports/FBgn0053703 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33703 IPR010512:Protein of unknown function DUF1091 CG33703 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033685 OSCP1 Organic solute carrier partner 1 http://flybase.org/reports/FBgn0033685 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from direct assay cilium assembly ; GO:0060271 | inferred from sequence model Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG13178, OSCP1, dOSCP1" IPR019332:Organic solute carrier protein 1 CG13178 11-Aug-17 DroID_v2017_08 "Drer\oscp1b, Drer\oscp1a" - Cele\R10F2.5 Xtro\oscp1 Mmus\Oscp1 Hsap\OSCP1 viable FBgn0011525 l(3)rP047 lethal (3) rP047 http://flybase.org/reports/FBgn0011525 - gene - - - l(3)rP047 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031374 Wdr62 WD repeat domain 62 http://flybase.org/reports/FBgn0031374 protein_coding_gene molecular_function ; GO:0003674 | no biological data available RNA splicing ; GO:0008380 | inferred from biological aspect of ancestor with PANTHER:PTN001108918 mitotic spindle organization ; GO:0007052 | inferred from sequence or structural similarity with HGNC:24502 regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype interphase microtubule organizing center ; GO:0031021 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from biological aspect of ancestor with PANTHER:PTN001108918 U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN001108918 mitotic spindle ; GO:0072686 | inferred from direct assay spindle pole ; GO:0000922 | inferred from sequence or structural similarity with HGNC:24502 precatalytic spliceosome ; GO:0071011 | inferred from biological aspect of ancestor with PANTHER:PTN001108918 "CG7337, Q0E8U7_DROME, Wdr62, wdr62" "IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR011042:Six-bladed beta-propeller, TolB-like" CG7337 11-Aug-17 DroID_v2017_08 "Drer\mapkbp1, Drer\katnb1, Drer\wdr62" Scer\SWD3 "Cele\H24G06.1, Cele\C42C1.4, Cele\F47G4.4" "Xtro\poc1b, Xtro\wdr62, Xtro\katnb1, Xtro\mapkbp1" "Mmus\Wdr62, Mmus\Katnb1, Mmus\Mapkbp1" "Hsap\KATNB1, Hsap\WDR62, Hsap\NEDD1, Hsap\MAPKBP1" viable DRSC00081 K -1.267318624 -0.276615726 0.345236554 -0.186662664 0.760361489 1.941071617 FBgn0267298 CR45734 - http://flybase.org/reports/FBgn0267298 non_protein_coding_gene - - - CR45734 - CR45734 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052126 tRNA:Pro-AGG-1-7 transfer RNA:Proline-AGG 1-7 http://flybase.org/reports/FBgn0052126 tRNA_gene CCU codon-amino acid adaptor activity ; GO:0033421 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033421 cytosol ; GO:0005829 | inferred by curator from GO:0033421 "AE002602.trna18-ProAGG, tRNA:P:AGG:AE002602-c, CR32126, chr3L.trna24-ProAGG, tRNA-Pro-AGG-1-7, tRNA:Pro-AGG-1-7, tRNA:CR32126, CCU" - CR32126 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017371 l(2)C54 lethal (2) C54 http://flybase.org/reports/FBgn0017371 - gene - - - "C54, l(2)C54" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0024995 CG2680 - http://flybase.org/reports/FBgn0024995 - protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with HGNC:30259 phosphatase activity ; GO:0016791 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:30259 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000445812 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:30259 "EG:100G10.4, CG2680, Phos2680, 3218519" "IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG2680 11-Aug-17 DroID_v2017_08 "Drer\pgp, Drer\lhpp, Drer\pdxp" Scer\PHO13 "Cele\F44E7.2, Cele\C53A3.2, Cele\C45E5.1, Cele\K02D10.1, Cele\C13C4.4, Cele\K09H11.7" - "Mmus\Pdxp, Mmus\Pgp, Mmus\Lhpp" "Hsap\LHPP, Hsap\PGP, Hsap\PDXP" viable FBgn0038902 CG6800 - http://flybase.org/reports/FBgn0038902 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity cyclin-dependent protein kinase activating kinase activity ; GO:0019912 | inferred from biological aspect of ancestor with PANTHER:PTN001173068 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity positive regulation of cyclin-dependent protein kinase activity ; GO:1904031 | inferred from biological aspect of ancestor with PANTHER:PTN001173068 protein phosphorylation ; GO:0006468 | non-traceable author statement nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001173068 "AC014407, CG6800" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG6800 11-Aug-17 DroID_v2017_08 "Drer\cdk7, Drer\cdk20" "Scer\KIN28, Scer\YGK3" Cele\dyf-18 Xtro\cdk7 "Mmus\Cdk7, Mmus\Cdk20" "Hsap\CDK20, Hsap\CDK7" viable FBgn0262532 CR43086 - http://flybase.org/reports/FBgn0262532 pseudogene_attribute - - - CR43086 - CR43086 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065280 l(2)SH2036 lethal (2) SH2036 http://flybase.org/reports/FBgn0065280 gene - - - "l(2)SH2036, l(2)SH2 2036" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028304 l(1)G0378 lethal (1) G0378 http://flybase.org/reports/FBgn0028304 gene - - - l(1)G0378 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0067873 Mod(Prat:bw)3-2 Mod(Prat:bw)3-2 http://flybase.org/reports/FBgn0067873 gene - - - "Mod-3-2, Mod(Prat:bw)3-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045477 Gr64c Gustatory receptor 64c http://flybase.org/reports/FBgn0045477 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype taste receptor activity ; GO:0008527 | non-traceable author statement "detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from electronic annotation with InterPro:IPR009318 sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype sensory perception of sweet taste ; GO:0050916 | inferred from genetic interaction with Gr64d, Gr64e, Gr64b, Gr64a, Gr64f sensory perception of taste ; GO:0050909 | non-traceable author statement" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009318 integral component of membrane ; GO:0016021 | non-traceable author statement "CG14986, CG32256, Gr64c, Dmel64c, Gr64, GR64c, gr64c" IPR009318:Gustatory receptor CG32256 11-Aug-17 DroID_v2017_08 - - - - - - taste perception defective FBgn0003304 rvn ravenoid http://flybase.org/reports/FBgn0003304 - gene - - - "raven, rvn" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036932 CG14184 - http://flybase.org/reports/FBgn0036932 protein_coding_gene - "positive regulation of MAPK cascade ; GO:0043410 | inferred from electronic annotation with InterPro:IPR028209 positive regulation of TOR signaling ; GO:0032008 | inferred from electronic annotation with InterPro:IPR026310, InterPro:IPR028209 lysosome organization ; GO:0007040 | inferred from electronic annotation with InterPro:IPR028209 regulation of receptor recycling ; GO:0001919 | inferred from electronic annotation with InterPro:IPR028209 endosome localization ; GO:0032439 | inferred from electronic annotation with InterPro:IPR028209 cholesterol homeostasis ; GO:0042632 | inferred from electronic annotation with InterPro:IPR028209 cellular response to amino acid stimulus ; GO:0071230 | inferred from mutant phenotype" Ragulator complex ; GO:0071986 | inferred from electronic annotation with InterPro:IPR028209 "anon-WO0118547.633, CG14184, p18, dp18" "IPR028209:LAMTOR1/MEH1, IPR026310:LAMTOR1-like" CG14184 11-Aug-17 DroID_v2017_08 Drer\lamtor1 - - Xtro\lamtor1 Mmus\Lamtor1 Hsap\LAMTOR1 viable FBgn0259539 B0821 - http://flybase.org/reports/FBgn0259539 gene - - - B0821 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "wing,macrochaeta,unguis,pretarsus" FBgn0260229 CG42503 - http://flybase.org/reports/FBgn0260229 protein_coding_gene molybdopterin synthase activity ; GO:0030366 | contributes_to inferred from sequence or structural similarity with UniProtKB:O96033 Mo-molybdopterin cofactor biosynthetic process ; GO:0006777 | inferred from sequence or structural similarity with UniProtKB:O96033 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:O96033 "CG42503, Dromel_CG10238_FBtr0084782_mocs2_uORF" "IPR016155:Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp, IPR010034:Molybdopterin converting factor, subunit 1, IPR012675:Beta-grasp domain, IPR003749:ThiamineS/Molybdopterin converting factor subunit 1, IPR028887:Molybdopterin synthase sulfur carrier subunit" CG42503 11-Aug-17 DroID_v2017_08 Drer\LOC103911725 - Cele\K10D2.7 - Mmus\Mocs2 Hsap\MOCS2 FBgn0002761 mit(1)11 mitotic 11 http://flybase.org/reports/FBgn0002761 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0039844 CG1607 - http://flybase.org/reports/FBgn0039844 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 L-amino acid transmembrane transporter activity ; GO:0015179 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 "CG1607, Cg1607" IPR002293:Amino acid/polyamine transporter I CG1607 11-Aug-17 DroID_v2017_08 "Drer\slc7a14a, Drer\zmp:0000001267, Drer\slc7a10b, Drer\slc7a10a, Drer\slc7a6, Drer\slc7a8a, Drer\slc7a7, Drer\si:dkeyp-120h9.1, Drer\slc7a8b, Drer\slc7a9, Drer\slc7a11, Drer\slc7a5, Drer\si:ch73-352p4.8" "Scer\MUP3, Scer\BAP3, Scer\TAT1, Scer\GNP1, Scer\MUP1, Scer\MMP1" "Cele\aat-3, Cele\aat-2, Cele\B0454.6, Cele\aat-1, Cele\F23F1.6, Cele\aat-4" "Xtro\slc7a10, Xtro\slc7a5, Xtro\LOC100492274, Xtro\slc7a11, Xtro\slc7a8, Xtro\slc7a6, Xtro\slc7a15, Xtro\slc7a9, Xtro\slc7a13, Xtro\slc7a7" "Mmus\Slc7a9, Mmus\Slc7a12, Mmus\Slc7a11, Mmus\Slc7a8, Mmus\Slc7a6, Mmus\Slc7a14, Mmus\Slc7a15, Mmus\Slc7a7, Mmus\Slc7a10, Mmus\Slc7a13, Mmus\Slc7a5" "Hsap\SLC7A14, Hsap\SLC7A9, Hsap\SLC7A8, Hsap\SLC7A13, Hsap\SLC7A11, Hsap\SLC7A10, Hsap\SLC7A7, Hsap\SLC7A5, Hsap\SLC7A6" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0010035 Est-20 Esterase 20 http://flybase.org/reports/FBgn0010035 - gene - - - Est-20 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010787 l(3)02732 lethal (3) 02732 http://flybase.org/reports/FBgn0010787 - gene - - - l(3)02732 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040715 CG15386 - http://flybase.org/reports/FBgn0040715 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15386 IPR027896:Protein of unknown function DUF4574 CG15386 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004122 l(2)43Ba lethal (2) 43Ba http://flybase.org/reports/FBgn0004122 - gene - - - "43Ba, l(2)43Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028573 prc pericardin http://flybase.org/reports/FBgn0028573 protein_coding_gene - cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype establishment or maintenance of apical/basal cell polarity ; GO:0035088 | traceable author statement heart development ; GO:0007507 | traceable author statement morphogenesis of an epithelium ; GO:0002009 | traceable author statement larval heart development ; GO:0007508 | inferred from mutant phenotype cell migration ; GO:0016477 | traceable author statement heart development ; GO:0007507 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from direct assay "Prc, Pc, EC11, CK01593, BEST:CK01593, CG5700, prc, pc, PC, PRC" IPR009765:Pericardin-like repeat CG5700 11-Aug-17 DroID_v2017_08 "Drer\col1a2, Drer\col2a1a, Drer\elnb, Drer\col1a1b, Drer\wu:fc38h03, Drer\si:ch211-196i2.1, Drer\col6a4a, Drer\col9a1b, Drer\col2a1b, Drer\zgc:153049, Drer\col1a1a, Drer\col28a1a, Drer\col11a1a, Drer\col6a3, Drer\LOC100538221, Drer\col9a2, Drer\col11a1b, Drer\col6a2, Drer\col5a1, Drer\col4a2, Drer\col7a1l, Drer\col12a1b, Drer\col11a2, Drer\col5a2a, Drer\col17a1b, Drer\LOC101884357, Drer\LOC101883924, Drer\col4a5, Drer\col16a1, Drer\si:dkey-61l1.4, Drer\si:ch211-106n13.3, Drer\col5a2b, Drer\si:dkey-225n22.4, Drer\col14a1a, Drer\col27a1a, Drer\col6a1, Drer\col27a1b, Drer\col9a1a, Drer\col4a6" - - "Xtro\col2a1, Xtro\col4a1, Xtro\col27a1, Xtro\col4a5, Xtro\col1a1, Xtro\col11a2, Xtro\col4a6, Xtro\col6a2, Xtro\col4a2, Xtro\col7a1, Xtro\col24a1, Xtro\col3a1, Xtro\col1a2, Xtro\col14a1, Xtro\col5a1, Xtro\LOC100486063" "Mmus\Col5a1, Mmus\Col6a4, Mmus\Vwa2, Mmus\Col9a3, Mmus\Col14a1, Mmus\Col5a3, Mmus\Tnn, Mmus\Col7a1, Mmus\Col4a5, Mmus\Col23a1, Mmus\Col11a1, Mmus\Col20a1, Mmus\4933412E24Rik, Mmus\Col19a1, Mmus\Col4a2, Mmus\Col22a1, Mmus\Col25a1, Mmus\Col1a1, Mmus\Col27a1, Mmus\Col13a1, Mmus\8030474K03Rik, Mmus\Col6a5, Mmus\Col2a1, Mmus\Col9a1, Mmus\Col11a2, Mmus\Col1a2, Mmus\Col24a1, Mmus\Col5a2, Mmus\Vwa1, Mmus\Col4a6, Mmus\Col6a1, Mmus\Col28a1, Mmus\Col6a6, Mmus\Col3a1, Mmus\Col16a1, Mmus\Col4a1, Mmus\Col17a1, Mmus\Col4a4, Mmus\Col6a3, Mmus\Col4a3" "Hsap\COL6A1, Hsap\COL27A1, Hsap\COLQ, Hsap\COL6A3, Hsap\COL24A1, Hsap\COL4A1, Hsap\COL9A2, Hsap\COL1A2, Hsap\COL1A1, Hsap\COL6A6, Hsap\COL2A1, Hsap\COL6A5, Hsap\COL4A2, Hsap\COL23A1, Hsap\COL16A1, Hsap\COL4A5, Hsap\COL20A1, Hsap\COL3A1, Hsap\COL5A1, Hsap\COL4A4, Hsap\COL14A1, Hsap\COL11A1, Hsap\COL19A1, Hsap\VWA1, Hsap\COL5A2, Hsap\COL11A2, Hsap\COL5A3, Hsap\COL22A1, Hsap\COL25A1, Hsap\COL4A3, Hsap\COL17A1, Hsap\COL9A3, Hsap\COL9A1, Hsap\COL7A1, Hsap\COL4A6, Hsap\VWA2" "viable,fertile,short lived,cell shape defective" "embryonic pericardial cell,cardioblast,embryonic dorsal vessel,embryonic/larval heart,embryonic/larval pericardial cell,embryonic/larval cardial cell,embryonic/larval alary muscle,embryonic/larval heart | third instar larval stage,embryonic/larval pericardial cell | third instar larval stage" FBgn0263987 spoon spoonbill http://flybase.org/reports/FBgn0263987 protein_coding_gene protein kinase A regulatory subunit binding ; GO:0034237 | inferred from electronic annotation with InterPro:IPR033104 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 "regulation of protein kinase A signaling ; GO:0010738 | inferred from electronic annotation with InterPro:IPR033104 maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded ; GO:0008070 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay long-term memory ; GO:0007616 | inferred from mutant phenotype dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype thermosensory behavior ; GO:0040040 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype centripetally migrating follicle cell migration ; GO:0060269 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of actin filament polymerization ; GO:0030837 | inferred from mutant phenotype inferred from genetic interaction with qua" mitochondrial outer membrane ; GO:0005741 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CG3249, spoon, yu, PKAAP, BcDNA:GM04319, mdi, AKAP Yu" "IPR002999:Tudor domain, IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR033104:A-kinase anchor protein 1, mitochondrial" CG3249 11-Aug-17 DroID_v2017_08 "Drer\akap1a, Drer\akap1b, Drer\tdrkh" - Cele\akap-1 Xtro\tdrkh "Mmus\Akap1, Mmus\Tdrkh" "Hsap\TDRKH, Hsap\AKAP1" FBgn0265672 CR44479 - http://flybase.org/reports/FBgn0265672 non_protein_coding_gene - - - "lincRNA.113, CR44479" - CR44479 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061098 l(3)S009647 lethal (3) S009647 http://flybase.org/reports/FBgn0061098 gene - - - "0096/47, l(3)S009647" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036020 CG8336 - http://flybase.org/reports/FBgn0036020 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130" - CG8336 "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR019734:Tetratricopeptide repeat, IPR029000:Cyclophilin-like domain" CG8336 11-Aug-17 DroID_v2017_08 "Drer\LOC100333141, Drer\ppil6, Drer\nktr, Drer\ppih, Drer\ppiab, Drer\ppid, Drer\ppib, Drer\ppiaa, Drer\si:ch1073-55a19.2, Drer\ppie, Drer\ppig" "Scer\CPR4, Scer\CPR6, Scer\CPR7" "Cele\cyn-6, Cele\Y17G9B.4, Cele\cyn-1, Cele\cyn-5, Cele\cyn-3, Cele\cyn-9, Cele\cyn-7, Cele\cyn-8, Cele\cyn-2, Cele\cyn-11" "Xtro\ranbp2, Xtro\nktr, Xtro\ppil6, Xtro\ppih, Xtro\ppid, Xtro\ppia, Xtro\ppie, Xtro\ppib, Xtro\ppic" "Mmus\Ppih, Mmus\Ranbp2, Mmus\Ppic, Mmus\Ppid, Mmus\Ppie, Mmus\Ppig, Mmus\Ppil6, Mmus\Nktr, Mmus\Ppib, Mmus\Ppif, Mmus\Ppia" "Hsap\RGPD8, Hsap\PPIG, Hsap\PPIH, Hsap\PPIAL4D, Hsap\PPIB, Hsap\RGPD1, Hsap\PPIAL4A, Hsap\RGPD5, Hsap\RGPD2, Hsap\RGPD4, Hsap\PPIL6, Hsap\NKTR, Hsap\PPIAL4G, Hsap\PPIC, Hsap\LOC105371242, Hsap\PPIA, Hsap\PPIF, Hsap\RGPD3, Hsap\RGPD6, Hsap\PPID, Hsap\PPIAL4C, Hsap\RANBP2, Hsap\PPIE" viable FBgn0262654 l(3)ED220-2 - http://flybase.org/reports/FBgn0262654 gene - - - l(3)ED220-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage,lethal" FBgn0028108 l(3)S069605a lethal (3) S069605a http://flybase.org/reports/FBgn0028108 gene - - - "l(3)S069605, l(3)S069605a" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267929 CR46210 - http://flybase.org/reports/FBgn0267929 non_protein_coding_gene - - - "CR46210, lincRNA.63" - CR46210 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060627 l(3)S087113b lethal (3) S087113b http://flybase.org/reports/FBgn0060627 gene - - - "0871/13, l(3)S087113b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266248 CR44943 - http://flybase.org/reports/FBgn0266248 non_protein_coding_gene - - - "CR44943, lincRNA.780" - CR44943 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019774 l(1)37 lethal (1) 37 http://flybase.org/reports/FBgn0019774 - gene - - - l(1)37 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0014308 l(3)neo64 lethal (3) neo64 http://flybase.org/reports/FBgn0014308 - gene - - - l(3)neo64 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062659 EP3263 EP3263 http://flybase.org/reports/FBgn0062659 gene - - - "EP(3)3263, EP3263" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020580 anon-59Ce anon-59Ce http://flybase.org/reports/FBgn0020580 - gene - - - anon-59Ce - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259645 B0968 - http://flybase.org/reports/FBgn0259645 gene - - - B0968 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "antennal segment,tarsal segment,unguis,arista" FBgn0004064 Bsg95C Blastoderm-specific transcript 95C http://flybase.org/reports/FBgn0004064 - gene - - - "bsg95C, Bsg95C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011787 mRpL12 mitochondrial ribosomal protein L12 http://flybase.org/reports/FBgn0011787 "FBgn0011362, FBgn0011514, FBgn0035940, FBgn0061393" protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P52815 chromatin binding ; GO:0003682 | inferred from genetic interaction with His1 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P52815 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype translation ; GO:0006412 | inferred from sequence or structural similarity mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 cell growth ; GO:0016049 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:P52815 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P52815 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "mRpL12, l(3)10534, mRpL7-L12, L7/L12, L7/12A, Mrp17, l(3)rL424, l(3)j4B2, CG5012, BcDNA:RE53508, L7" "IPR008932:Ribosomal protein L7/L12, oligomerisation, IPR013823:Ribosomal protein L7/L12, C-terminal, IPR014719:Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like, IPR000206:Ribosomal protein L7/L12" CG5012 11-Aug-17 DroID_v2017_08 "Drer\slc25a14, Drer\si:ch1073-100f3.2, Drer\mrpl12, Drer\slc25a11, Drer\ucp2, Drer\slc25a10" Scer\MNP1 "Cele\slc-25A10, Cele\ucp-4, Cele\mrpl-12" "Xtro\slc25a27, Xtro\slc25a10, Xtro\rangrf, Xtro\mrpl12, Xtro\ucp1, Xtro\ucp2, Xtro\slc25a30" "Mmus\Slc25a10, Mmus\Ucp1, Mmus\Slc25a14, Mmus\Ucp2, Mmus\Ucp3, Mmus\Mrpl12, Mmus\Slc25a27, Mmus\Slc25a11, Mmus\Slc25a30" "Hsap\UCP3, Hsap\UCP2, Hsap\UCP1, Hsap\SLC25A27, Hsap\MRPL12, Hsap\SLC25A14, Hsap\SLC25A10, Hsap\SLC25A30, Hsap\SLC25A11" "lethal,recessive,small body,lethal - all die before end of larval stage,some die during larval stage,decreased cell number,cell autonomous,somatic clone,viable,visible" "mitochondrion | somatic clone,trichogen cell" DRSC10467 K 0.709586538 0.6313913 -0.005328982 0.212731362 1.869371354 0.606807903 FBgn0034808 CG9896 - http://flybase.org/reports/FBgn0034808 protein_coding_gene - - - CG9896 - CG9896 11-Aug-17 DroID_v2017_08 - - Cele\C50D2.6 - - - "viable,fertile" DRSC04594 K 1.133703707 -0.26794073 0.004146416 -0.038912401 -1.81523824 -0.261263633 FBgn0266924 T:nls-Ude nuclear localisation signal of Ude http://flybase.org/reports/FBgn0266924 engineered_tag - - - T:nls-Ude - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261996 CG42814 - http://flybase.org/reports/FBgn0261996 protein_coding_gene "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ; GO:0016818 | inferred from electronic annotation with InterPro:IPR004385 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR004385" - - "CG42814, CG31063, CG6001" "IPR015797:NUDIX hydrolase domain-like, IPR004385:Nucleoside diphosphate pyrophosphatase, IPR000086:NUDIX hydrolase domain" CG42814 11-Aug-17 DroID_v2017_08 Drer\nudt14 - Cele\C50F4.16 - Mmus\Nudt14 Hsap\NUDT14 "viable,fertile" FBgn0013754 Bri Bri http://flybase.org/reports/FBgn0013754 - gene - - - Bri - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" macrochaeta FBgn0052571 TwdlX TweedleX http://flybase.org/reports/FBgn0052571 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlX, CG32571" IPR004145:Domain of unknown function DUF243 CG32571 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060324 l(3)S146607b lethal (3) S146607b http://flybase.org/reports/FBgn0060324 gene - - - "1466/07, l(3)S146607b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0040564 CG12417 - http://flybase.org/reports/FBgn0040564 protein_coding_gene - - - CG12417 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267735 CR46066 - http://flybase.org/reports/FBgn0267735 non_protein_coding_gene - - - "CR46066, Mgn3779" - CR46066 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065071 snoRNA:Or-CD10 - http://flybase.org/reports/FBgn0065071 snoRNA_gene - - - "Dm-284, snoR284, CR33663, snoRNA:Or-CD10, DmOr_cd10(SnoR284), snoRNA:284, chrX:6376887..6376991" - CR33663 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260325 GSd303 - http://flybase.org/reports/FBgn0260325 gene - - - GSd303 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265464 Traf6 TNF-receptor-associated factor 6 http://flybase.org/reports/FBgn0265464 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR013323 protein binding ; GO:0005515 | inferred from physical interaction with ECSIT zinc ion binding ; GO:0008270 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VWS4 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12036" positive regulation of JNK cascade ; GO:0046330 | inferred from electronic annotation with InterPro:IPR027138 activation of NF-kappaB-inducing kinase activity ; GO:0007250 | inferred from electronic annotation with InterPro:IPR027138 cell death ; GO:0008219 | inferred from genetic interaction with egr protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12036 negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with dx inferred from genetic interaction with N inferred from genetic interaction with krz inferred from physical interaction with N regulation of I-kappaB kinase/NF-kappaB signaling ; GO:0043122 | inferred from mutant phenotype regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | traceable author statement innate immune response ; GO:0045087 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement stress-activated protein kinase signaling cascade ; GO:0031098 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | NOT inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with Traf4 "CG10961, Traf6, dTRAF2, dtraf2, TRAF6, TRAF2, TRAF, dTRAF6, dTraf2, DTRAF2, Traf2, EP325, dTraf6, traf2" "IPR001841:Zinc finger, RING-type, IPR002083:MATH/TRAF domain, IPR008974:TRAF-like, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027138:TNF receptor-associated factor 4" CG10961 11-Aug-17 DroID_v2017_08 "Drer\traf5, Drer\LOC100005446, Drer\traf3, Drer\traf2a, Drer\traf4a, Drer\traf6, Drer\traf1, Drer\traf2b" - "Cele\trf-1, Cele\rnf-5, Cele\Y110A7A.2" "Xtro\traf3, Xtro\traf6, Xtro\traf4, Xtro\traf5, Xtro\traf2" "Mmus\Traf4, Mmus\Traf3, Mmus\Traf1, Mmus\Traf6, Mmus\Traf2, Mmus\Traf5" "Hsap\TRAF4, Hsap\TRAF2, Hsap\TRAF1, Hsap\TRAF3, Hsap\TRAF6, Hsap\TRAF5" FBgn0002744 mib miniature bristles http://flybase.org/reports/FBgn0002744 - gene - - - mib - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male,male sterile,body color defective" "macrochaeta,wing,adult thorax,tergite,posterior" FBgn0266303 CR44968 - http://flybase.org/reports/FBgn0266303 non_protein_coding_gene - - - CR44968 - CR44968 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029026 l(3)77ABf lethal (3) 77ABf http://flybase.org/reports/FBgn0029026 gene - - - l(3)77ABf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0052301 CG32301 - http://flybase.org/reports/FBgn0052301 protein_coding_gene guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 adenylate cyclase activity ; GO:0004016 | non-traceable author statement "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 notum development ; GO:0007477 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 chaeta development ; GO:0022416 | inferred from mutant phenotype cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG8970, AC, CG32301" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase" CG32301 11-Aug-17 DroID_v2017_08 "Drer\adcy7, Drer\adcy3a, Drer\adcy8, Drer\si:ch211-132f19.7, Drer\adcy1a, Drer\adcy5, Drer\adcy2b, Drer\adcy2a, Drer\adcy6a, Drer\adcy6b, Drer\adcy1b, Drer\si:dkey-206f10.1" - "Cele\acy-4, Cele\acy-2" "Xtro\dnajc27, Xtro\adcy1, Xtro\adcy4, Xtro\adcy7, Xtro\adcy6" "Mmus\Adcy8, Mmus\Adcy6, Mmus\Adcy4, Mmus\Adcy2, Mmus\Adcy5, Mmus\Adcy7, Mmus\Adcy1, Mmus\Adcy3" "Hsap\ADCY8, Hsap\ADCY3, Hsap\ADCY6, Hsap\ADCY2, Hsap\ADCY5, Hsap\ADCY1, Hsap\ADCY4, Hsap\ADCY7" "viable,body color defective" "mesothoracic tergum,macrochaeta" FBgn0267472 CR45822 - http://flybase.org/reports/FBgn0267472 non_protein_coding_gene - - - CR45822 - CR45822 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033760 CG8785 - http://flybase.org/reports/FBgn0033760 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 CG8785 "IPR013057:Amino acid transporter, transmembrane domain" CG8785 11-Aug-17 DroID_v2017_08 "Drer\slc36a4, Drer\slc36a1" "Scer\AVT7, Scer\AVT3, Scer\AVT4" "Cele\slc-36.2, Cele\slc-36.5, Cele\F21D12.3, Cele\slc-36.4, Cele\slc-36.3, Cele\Y43F4B.7, Cele\skat-1" "Xtro\slc36a4, Xtro\slc36a1" "Mmus\Slc36a4, Mmus\Slc36a3, Mmus\Slc36a2, Mmus\Slc36a1" "Hsap\SLC36A3, Hsap\SLC36A1, Hsap\SLC36A2, Hsap\SLC36A4" "viable,visible" trichogen cell FBgn0005164 l(2)G552 lethal (2) G552 http://flybase.org/reports/FBgn0005164 - gene - - - l(2)G552 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022244 l(2)k02107a lethal (2) k02107a http://flybase.net/reports/FBgn0022244.html gene l(2)k02107 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0053420 5SrRNA:CR33420 5SrRNA:CR33420 http://flybase.org/reports/FBgn0053420 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33420, 5SrRNA:CR33420" - CR33420 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039525 CG5646 - http://flybase.org/reports/FBgn0039525 protein_coding_gene L-ornithine transmembrane transporter activity ; GO:0000064 | inferred from biological aspect of ancestor with PANTHER:PTN000641358 transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with SGD:S000000308 mitochondrial ornithine transport ; GO:0000066 | inferred from biological aspect of ancestor with PANTHER:PTN000641358 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000641358 CG5646 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG5646 11-Aug-17 DroID_v2017_08 "Drer\slc25a45, Drer\LOC100329459, Drer\slc25a15b, Drer\slc25a48, Drer\slc25a20, Drer\slc25a15a, Drer\slc25a47b, Drer\si:dkey-150i13.2, Drer\slc25a47a" "Scer\CRC1, Scer\ORT1, Scer\YMC1, Scer\YMC2" "Cele\T10F2.2, Cele\R07B7.10" "Xtro\slc25a20.2, Xtro\slc25a20, Xtro\slc25a47, Xtro\slc25a29, Xtro\slc25a45, Xtro\slc25a48" "Mmus\Slc25a20, Mmus\Slc25a48, Mmus\Slc25a2, Mmus\Slc25a47, Mmus\Slc25a45, Mmus\Slc25a29, Mmus\Slc25a15" "Hsap\SLC25A20, Hsap\SLC25A45, Hsap\SLC25A15, Hsap\SLC25A29, Hsap\SLC25A48, Hsap\SLC25A2, Hsap\SLC25A47" viable FBgn0043455 CG5986 - http://flybase.org/reports/FBgn0043455 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with SGD:S000002188 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002188" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000300188 U2-type prespliceosome ; GO:0071004 | inferred from sequence or structural similarity with SGD:S000002188 "BEST:LP03871, CG5986" IPR024974:Sde2 N-terminal domain CG5986 11-Aug-17 DroID_v2017_08 Drer\sde2 Scer\PRP9 Cele\F53F4.14 Xtro\sde2 Mmus\Sde2 Hsap\SDE2 "visible,viable" "eye,dorsocentral bristle,scutellar bristle" FBgn0001471 l(1)8Ad lethal (1) 8Ad http://flybase.org/reports/FBgn0001471 - gene - - - "l(1)A86, l(1)8Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085576 CG41250 - http://flybase.org/reports/FBgn0085576 protein_coding_gene - - - CG41250 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002608 M(2)d Minute (2) d http://flybase.org/reports/FBgn0002608 - gene - - - M(2)d - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024331 Mdp-1 Macrophage derived proteoglycan-1 http://flybase.org/reports/FBgn0024331 - gene - - - "MDP-1, Mdp-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050082 CG30082 - http://flybase.org/reports/FBgn0050082 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "CG30082, CR30082" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG30082 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.9, Drer\si:dkey-21e2.7, Drer\si:dkey-21e2.15, Drer\si:ch211-165b19.5, Drer\si:dkey-21e2.12, Drer\gzm3, Drer\st14b" - - - "Mmus\Mcpt9, Mmus\Gzmc, Mmus\Gzmd, Mmus\Gzmg, Mmus\Mcpt8, Mmus\Gzme, Mmus\Mcpt4, Mmus\Cma2, Mmus\Gzmb, Mmus\Gzmf, Mmus\Klk6, Mmus\Cma1, Mmus\Ctsg, Mmus\Mcpt1" "Hsap\GZMH, Hsap\CMA1, Hsap\CTSG, Hsap\GZMB" FBgn0014038 Su(tor)1-1 Su(tor)1-1 http://flybase.org/reports/FBgn0014038 - gene - - - Su(tor)1-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0265807 CR44596 - http://flybase.org/reports/FBgn0265807 non_protein_coding_gene - - - "lincRNA.122, CR44596" - CR44596 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001027 Fs(3)Apc Female sterile (3) Apc http://flybase.org/reports/FBgn0001027 - gene - - - "Apc, fs(3)Apc, Fs(3)Sz1, Fs(3)Apc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,dominant" "egg,maternal effect,dorsal appendage" FBgn0082374 EP1547 EP1547 http://flybase.org/reports/FBgn0082374 gene - - - EP1547 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0065640 l(2)SH0761 lethal (2) SH0761 http://flybase.org/reports/FBgn0065640 gene - - - "l(2)SH0761, l(2)SH2 0761" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267609 CR45947 - http://flybase.org/reports/FBgn0267609 pseudogene_attribute - - - CR45947 - CR45947 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086031 snoRNA:Me28S-U1230 - http://flybase.org/reports/FBgn0086031 snoRNA_gene - - - "snoRNA:Me28S-U1230, Me28S-Um1230, CR34660" - CR34660 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046655 anon-38D.1 anon-38D.1 http://flybase.org/reports/FBgn0046655 gene - - - "38D.1, anon-38D.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017572 Mo25 Mo25 http://flybase.org/reports/FBgn0017572 FBgn0010713 protein_coding_gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "dMo25, l(3)00274, CG4083, Mo25, Dmo25, mo25" "IPR013878:Mo25-like, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG4083 11-Aug-17 DroID_v2017_08 "Drer\cab39l1, Drer\cab39l, Drer\cab39" Scer\HYM1 "Cele\mop-25.1, Cele\mop-25.3, Cele\mop-25.2" "Xtro\cab39l, Xtro\cab39" "Mmus\Cab39l, Mmus\Cab39" "Hsap\CAB39, Hsap\CAB39L" "visible,lethal,recessive,partially,rescuable maternal effect,somatic clone,lethal - all die before end of larval stage,some die during larval stage,viable,body color defective" "wing vein,embryonic/first instar larval cuticle,chaeta,somatic clone,supernumerary,wing margin,mesothoracic tergum" FBgn0065467 l(2)SH1338 lethal (2) SH1338 http://flybase.org/reports/FBgn0065467 gene - - - "l(2)SH1338, l(2)SH2 1338" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001258 ImpL3 Ecdysone-inducible gene L3 http://flybase.org/reports/FBgn0001258 FBgn0035698 protein_coding_gene "L-lactate dehydrogenase activity ; GO:0004459 | inferred from electronic annotation with InterPro:IPR011304, InterPro:IPR018177" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR015955 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001236, InterPro:IPR001557, InterPro:IPR011304, InterPro:IPR015955, InterPro:IPR018177, InterPro:IPR022383 carboxylic acid metabolic process ; GO:0019752 | inferred from electronic annotation with InterPro:IPR001557 myoblast fusion ; GO:0007520 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011304 "dLdh, LDH, CG10160, dmLDH, IMP-L3, Imp-L3, Ldh, ImpL3, Impl3, Ld, dLdha, IMPL3, dLDH, lincRNA.S4223, impl3, ldh, Impl 3" "IPR015955:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR018177:L-lactate dehydrogenase, active site, IPR001236:Lactate/malate dehydrogenase, N-terminal, IPR001557:L-lactate/malate dehydrogenase, IPR011304:L-lactate dehydrogenase, IPR016040:NAD(P)-binding domain, IPR022383:Lactate/malate dehydrogenase, C-terminal" CG10160 11-Aug-17 DroID_v2017_08 "Drer\ldhba, Drer\ldha, Drer\uevld, Drer\ldhbb" - Cele\ldh-1 "Xtro\ldhb, Xtro\ldha, Xtro\uevld" "Mmus\Ldhal6b, Mmus\Ldha, Mmus\Uevld, Mmus\Ldhb, Mmus\Ldhc" "Hsap\UEVLD, Hsap\LDHB, Hsap\LDHA, Hsap\LDHC, Hsap\LDHAL6A, Hsap\LDHAL6B" " embryonic stage | stage >=15 , larval stage , embryonic stage && larval stage && adult stage " " embryonic/larval posterior spiracle

, imaginal disc

, pharyngeal muscle

, embryonic/larval proventriculus

" " prepupal stage , embryonic stage | stage >=15 , embryonic stage " " tarsal segment

, embryonic/larval posterior spiracle

, ventral thoracic disc

, pharyngeal muscle

, embryonic/larval somatic muscle

, embryonic/larval proventriculus

, tibia | presumptive

" viable "embryonic/larval somatic muscle,embryonic myoblast" DRSC11198 E 1.264845478 0.962645883 1.71608137 0.351887407 -0.146074946 0.163819377 FBgn0267977 mh maternal haploid http://flybase.org/reports/FBgn0267977 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006642 polyubiquitin binding ; GO:0031593 | inferred from biological aspect of ancestor with PANTHER:PTN000476753 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR006642 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from biological aspect of ancestor with PANTHER:PTN000476753 UV protection ; GO:0009650 | inferred from mutant phenotype germinal vesicle ; GO:0042585 | inferred from direct assay male pronucleus ; GO:0001940 | inferred from direct assay "mh, CG9203, fs(1)A1182, fs(1)1182" "IPR006640:SprT-like, IPR006642:Zinc finger, Rad18-type putative" CG9203 11-Aug-17 DroID_v2017_08 Drer\sprtn - Cele\dvc-1 Xtro\sprtn Mmus\Sprtn Hsap\SPRTN FBgn0011927 tRNA:iMet-CAT-1-4 transfer RNA:initiator Methionine-CAT 1-4 http://flybase.org/reports/FBgn0011927 "FBgn0003814, FBgn0052142, FBgn0060145" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "CR32142, AE002602.trna2-MetCAT, tRNA:M:CAT:AE002602-a, tRNA:met3:70Fa, tRNA[Met-ATG], chr3L.trna36-MetCAT, tRNA-iMet-CAT-1-4, tRNA:iMet-CAT-1-4, tRNA:M3:70Fa" - CR32142 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020641 Lcp65Ad Lcp65Ad http://flybase.org/reports/FBgn0020641 FBgn0064917 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence or structural similarity chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "DMCLP65d, Lcp-d, DCP1, CG6955, BcDNA:LP05231, Lcp65Ad, DmelLcp65Ad" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG6955 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " embryonic stage , pupal stage | 7-13 hr , larval stage " DRSC11211 K -0.438624407 0.595835479 0.026066446 -0.151176829 -0.014813563 2.170699421 FBgn0033380 Phax Phosphorylated adaptor for RNA export http://flybase.org/reports/FBgn0033380 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with MGI:MGI:1891839 snRNA export from nucleus ; GO:0006408 | inferred from biological aspect of ancestor with PANTHER:PTN000319972 snRNA export from nucleus ; GO:0006408 | inferred from sequence or structural similarity with MGI:MGI:1891839 nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:1891839 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:1891839 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000319972 "CG8069, dPHAX, BEST:GH22533, Phax" "IPR019385:Phosphorylated adapter RNA export protein, RNA-binding domain" CG8069 11-Aug-17 DroID_v2017_08 Drer\phax - Cele\Y71H2B.2 Xtro\phax Mmus\Phax Hsap\PHAX viable FBgn0025767 l(3)89Ci lethal (3) 89Ci http://flybase.org/reports/FBgn0025767 - gene - - - "l(3)M238, l(3)89Ci" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084032 CG41472 - http://flybase.org/reports/FBgn0084032 protein_coding_gene - - - CG41472 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004951 1688-10Ea 1.688 satellite-related 10Ea http://flybase.org/reports/FBgn0004951 - repeat_region - - - "1.688, 1688-10E[d], 1688-10Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038115 CG7966 - http://flybase.org/reports/FBgn0038115 protein_coding_gene selenium binding ; GO:0008430 | inferred from electronic annotation with InterPro:IPR008826 - - CG7966 "IPR008826:Selenium-binding protein, IPR011042:Six-bladed beta-propeller, TolB-like" CG7966 11-Aug-17 DroID_v2017_08 Drer\selenbp1 - "Cele\Y37A1B.5, Cele\R11G10.2" Xtro\selenbp1 "Mmus\Selenbp2, Mmus\Selenbp1" Hsap\SELENBP1 viable FBgn0263994 CG43737 - http://flybase.org/reports/FBgn0263994 protein_coding_gene - - - "CG43737, CG15028, CG15029, Dm_X:77844" - CG43737 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025005 E(var)166-7 E(var)166-7 http://flybase.org/reports/FBgn0025005 - gene - - - "E-166/7, E(var)166-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030651 CG12706 - http://flybase.org/reports/FBgn0030651 protein_coding_gene - - - CG12706 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020646 Lcp65APsi Lcp65APsi http://flybase.org/reports/FBgn0020646 FBgn0042116 pseudogene_attribute - - - "Lcp65APsi, Lcp-a[Psi], Lcp-Psi, LCP65Aapsi, DCP4[Psi], CG18775, CR18775" - CR18775 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024877 l(2)52Fd lethal (2) 52Fd http://flybase.org/reports/FBgn0024877 - gene - - - "E3.27, l(2)52Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000848 fs(1)M36 female sterile (1) M36 http://flybase.org/reports/FBgn0000848 - gene - - - fs(1)M36 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" FBgn0039183 Dis3 Dis3 http://flybase.org/reports/FBgn0039183 protein_coding_gene 3'-5'-exoribonuclease activity ; GO:0000175 | inferred from biological aspect of ancestor with PANTHER:PTN000599170 exoribonuclease activity ; GO:0004532 | inferred from direct assay endoribonuclease activity ; GO:0004521 | inferred from direct assay mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype nuclear RNA surveillance ; GO:0071027 | inferred from mutant phenotype rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000599170 defense response to virus ; GO:0051607 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype nuclear lamina ; GO:0005652 | inferred from direct assay exosome (RNase complex) ; GO:0000178 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000005381 inferred from direct assay "CG6413, Dis3, dDis3, taz, dRrp44, Rrp44, dis3, Taz" "IPR012340:Nucleic acid-binding, OB-fold, IPR002716:PIN domain, IPR033770:Exosome complex exonuclease RRP44, S1 domain, IPR033771:Rrp44-like cold shock domain, IPR029060:PIN domain-like, IPR022966:Ribonuclease II/R, conserved site" CG6413 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97a13.6, Drer\dis3l2, Drer\dis3l, Drer\helz2, Drer\dis3" "Scer\SSD1, Scer\DIS3, Scer\DSS1" "Cele\disl-2, Cele\dis-3" "Xtro\dis3l, Xtro\dis3" "Mmus\Dis3, Mmus\Helz2, Mmus\Dis3l, Mmus\Dis3l2" "Hsap\DIS3L, Hsap\DIS3, Hsap\DIS3L2, Hsap\HELZ2" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" DRSC16034 I 2.586474344 0.837758563 -0.474001732 -1.488087723 -0.888544752 0.737121566 FBgn0266752 CR45225 - http://flybase.org/reports/FBgn0266752 non_protein_coding_gene - - - CR45225 - CR45225 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033185 CG1603 - http://flybase.org/reports/FBgn0033185 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D - CG1603 "IPR006578:MADF domain, IPR013087:Zinc finger C2H2-type" CG1603 11-Aug-17 DroID_v2017_08 "Drer\thap3, Drer\si:ch211-40k21.9, Drer\si:ch73-389k6.1, Drer\si:dkey-228b2.6, Drer\thap1, Drer\arl14ep, Drer\zgc:113364" - Cele\mnm-2 "Xtro\thap5, Xtro\thap1" "Mmus\Thap1, Mmus\Thap3, Mmus\Thap2, Mmus\Zfp995, Mmus\Gm13212, Mmus\Zfp980" "Hsap\THAP5, Hsap\THAP2, Hsap\THAP8, Hsap\ZNF711, Hsap\THAP3, Hsap\THAP1, Hsap\ZBTB18, Hsap\ZNF664" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC06602 K 1.215293981 0.561216313 0.147574555 0.157335266 -2.00008282 -1.464007171 FBgn0010894 sinu sinuous http://flybase.org/reports/FBgn0010894 FBgn0035613 protein_coding_gene - "regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype heart process ; GO:0003015 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004031 septate junction ; GO:0005918 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "sinu, Sinu, CG10624, i8, l(3)06524, 6524" IPR004031:PMP-22/EMP/MP20/Claudin superfamily CG10624 11-Aug-17 DroID_v2017_08 "Drer\cacng3a, Drer\lim2.4" - "Cele\str-73, Cele\srd-31" - - - "lethal,recessive,partially lethal - majority die,visible" "embryonic/larval dorsal trunk,embryonic/larval transverse connective,embryonic/larval tracheal system,dorsal trunk primordium,heart primordium,septate junction,taenidial fold,presumptive embryonic/larval tracheal system,trichogen cell" FBgn0050178 CG30178 - http://flybase.org/reports/FBgn0050178 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 - - "CG17263, CG30178" "IPR001781:Zinc finger, LIM-type" CG30178 11-Aug-17 DroID_v2017_08 "Drer\pdlim5a, Drer\pdlim4, Drer\pdlim2, Drer\si:rp71-15d4.1, Drer\pxnb, Drer\pdlim3b, Drer\pdlim3a, Drer\fhl3b, Drer\pxna, Drer\csrp2, Drer\pdlim5b, Drer\pdlim1, Drer\zyx, Drer\fhl3a" "Scer\LRG1, Scer\PXL1" "Cele\Y1A5A.1, Cele\pxl-1, Cele\alp-1" "Xtro\pxn, Xtro\pdlim3, Xtro\pdlim1, Xtro\pdlim4, Xtro\fhl5, Xtro\fhl3, Xtro\tgfb1i1, Xtro\pdlim7, Xtro\pdlim5, Xtro\fhl2" "Mmus\Tgfb1i1, Mmus\Pdlim4, Mmus\Lpxn, Mmus\Pdlim1, Mmus\Arhgap28, Mmus\Ldb3, Mmus\Fhl2, Mmus\Pdlim2, Mmus\Pdlim7, Mmus\Pdlim3, Mmus\Fhl1, Mmus\Fhl3, Mmus\Fhl4, Mmus\Pdlim5, Mmus\Pxn, Mmus\Limd2, Mmus\Fhl5" "Hsap\PXN, Hsap\TGFB1I1, Hsap\LPXN, Hsap\PDLIM4, Hsap\ARHGAP28, Hsap\FHL3, Hsap\PDLIM7, Hsap\FHL5, Hsap\PDLIM1, Hsap\LIMD2, Hsap\FHL1, Hsap\PDLIM3, Hsap\LDB3, Hsap\PDLIM5, Hsap\FHL2, Hsap\PDLIM2" "lethal,recessive,viable" FBgn0067738 l(1)G0325 lethal (1) G0325 http://flybase.org/reports/FBgn0067738 gene - - - l(1)G0325 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035258 CG13931 - http://flybase.org/reports/FBgn0035258 protein_coding_gene - - - CG13931 - CG13931 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037133 CG7370 - http://flybase.org/reports/FBgn0037133 protein_coding_gene - - - "BcDNA:GM07065, CG7370" - CG7370 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0265192 Snp Snipper http://flybase.org/reports/FBgn0265192 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 3'-5'-exoribonuclease activity ; GO:0000175 | inferred from direct assay single-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008310 | inferred from direct assay double-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008311 | inferred from direct assay "histone mRNA catabolic process ; GO:0071044 | NOT inferred from mutant phenotype RNA phosphodiester bond hydrolysis, exonucleolytic ; GO:0090503 | inferred from direct assay exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000467 | inferred from biological aspect of ancestor with PANTHER:PTN000548993" - "CG44248, Snp, CG6393, CG11478, CG30327, CG42257" "IPR012337:Ribonuclease H-like domain, IPR013520:Exonuclease, RNase T/DNA polymerase III" CG44248 11-Aug-17 DroID_v2017_08 "Drer\eri1, Drer\eri2, Drer\rnpc3, Drer\rbm41" - "Cele\R02D3.8, Cele\M02B7.2, Cele\crn-4, Cele\eri-1" "Xtro\rnpc3, Xtro\eri2" "Mmus\Eri1, Mmus\Eri3, Mmus\Rbm41, Mmus\Rnpc3, Mmus\Eri2" "Hsap\ERI3, Hsap\ERI2, Hsap\ERI1, Hsap\RBM41, Hsap\RNPC3" FBgn0014361 Mst58.1 Male-specific transcript 58.1 http://flybase.org/reports/FBgn0014361 - gene - - - Mst58.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082640 Pvr::Hsap\PDGFRA PGFRalpha http://flybase.org/reports/FBgn0082640 engineered_fusion_gene - - - "Pvr::Hsap\PGFRalpha, Pvr::Hsap\PDGFRA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039536 unc80 uncoordinated 80 http://flybase.org/reports/FBgn0039536 protein_coding_gene cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with UniProtKB:Q9XV66 cation homeostasis ; GO:0055080 | inferred from sequence or structural similarity with UniProtKB:Q9XV66 locomotor rhythm ; GO:0045475 | inferred from mutant phenotype cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with UniProtKB:Q9XV66 "CG18437, unc80, UNC80, Dunc80" "IPR031542:Cation channel complex component UNC80, N-terminal" CG18437 11-Aug-17 DroID_v2017_08 Drer\unc80 - Cele\unc-80 Xtro\unc80 Mmus\Unc80 Hsap\UNC80 "circadian behavior defective,viable" FBgn0035722 CG10075 - http://flybase.org/reports/FBgn0035722 protein_coding_gene - Golgi organization ; GO:0007030 | inferred from mutant phenotype - CG10075 "IPR007129:Ubiquinol-cytochrome c chaperone, CBP3, IPR021150:Ubiquinol-cytochrome c chaperone/UPF0174" CG10075 11-Aug-17 DroID_v2017_08 Drer\uqcc1 Scer\CBP3 "Cele\F59A3.4, Cele\C35D10.5" "Xtro\uqcc1, Xtro\slc39a11" "Mmus\Uqcc1, Mmus\Slc39a11" "Hsap\SLC39A11, Hsap\UQCC1" "partially lethal - majority die,some die during pupal stage,viable" FBgn0260795 NaPi-III Na[+]-dependent inorganic phosphate cotransporter type III http://flybase.org/reports/FBgn0260795 protein_coding_gene inorganic phosphate transmembrane transporter activity ; GO:0005315 | inferred from electronic annotation with InterPro:IPR001204 sodium-dependent phosphate transmembrane transporter activity ; GO:0015321 | inferred from mutant phenotype sodium-dependent phosphate transport ; GO:0044341 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001204 "CG7628, CR32078, dPit, NaPi-III, CG42575, Dromel_CG7628_FBtr0076213_mORF" "IPR001204:Phosphate transporter, IPR015943:WD40/YVTN repeat-like-containing domain" CG42575 11-Aug-17 DroID_v2017_08 "Drer\slc20a2, Drer\slc20a1b, Drer\slc20a1a" Scer\PHO89 "Cele\pitr-6, Cele\pitr-4, Cele\pitr-5, Cele\pitr-1, Cele\pitr-3, Cele\pitr-2" "Xtro\slc20a2, Xtro\slc20a1" "Mmus\Slc20a1, Mmus\Slc20a2" "Hsap\SLC20A2, Hsap\SLC20A1" FBgn0005261 l(3)SG81 lethal (3) SG81 http://flybase.org/reports/FBgn0005261 - gene - - - l(3)SG81 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0004736 l(3)85Dc lethal (3) 85Dc http://flybase.org/reports/FBgn0004736 - gene - - - l(3)85Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0046845 ird21 immune response deficient 21 http://flybase.org/reports/FBgn0046845 gene molecular_function ; GO:0003674 | no biological data available humoral immune response ; GO:0006959 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ird21 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,immune response defective" FBgn0001225 Hsp26 Heat shock protein 26 http://flybase.org/reports/FBgn0001225 FBgn0010231 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A unfolded protein binding ; GO:0051082 | inferred from direct assay chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay protein refolding ; GO:0042026 | inferred from direct assay cold acclimation ; GO:0009631 | inferred from expression pattern determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model response to heat ; GO:0009408 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "Dmel23.0, Hsp26, hsp26, 26K, CG4183, DmHsp26, HSP26, hsp 26, 26, small hsp locus 67B, Hsp 26" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4183 11-Aug-17 DroID_v2017_08 "Drer\hspb6, Drer\hspb9, Drer\si:dkey-1k23.3, Drer\cryaa, Drer\hspb7, Drer\hspb1, Drer\hspb8, Drer\hspb3, Drer\hspb2, Drer\hspb15, Drer\hspb11, Drer\cryaba, Drer\hspb12, Drer\cryabb" - "Cele\hsp-43, Cele\hsp-12.6, Cele\hsp-12.2, Cele\hsp-16.1, Cele\hsp-16.2, Cele\hsp-16.41, Cele\sip-1, Cele\hsp-16.11, Cele\hsp-12.3, Cele\hsp-16.48, Cele\F08H9.4, Cele\hsp-16.49, Cele\hsp-12.1, Cele\hsp-17, Cele\Y55F3BR.6, Cele\ZK1128.7, Cele\hsp-25, Cele\F08H9.3" "Xtro\hspb6, Xtro\uqcrh, Xtro\hspb3, Xtro\hspb8, Xtro\cryab, Xtro\hspb1, Xtro\hsp30d, Xtro\hspb2, Xtro\hsp30e, Xtro\cryaa" "Mmus\Hspb2, Mmus\Cryab, Mmus\Hspb6, Mmus\Hspb1, Mmus\Hspb7, Mmus\Cryaa, Mmus\Hspb9, Mmus\Hspb8, Mmus\Hspb3" "Hsap\LOC102724652, Hsap\HSPB6, Hsap\HSPB9, Hsap\HSPB7, Hsap\CRYAB, Hsap\HSPB8, Hsap\HSPB1, Hsap\CRYAA, Hsap\HSPB2, Hsap\HSPB3" " embryonic stage | early , prepupal stage " "viable,fertile,long lived,male,chemical resistant,female fertile,reduced" FBgn0063385 snoRNA:Me28S-A3407a - http://flybase.org/reports/FBgn0063385 snoRNA_gene - - - "U29snoRNA, CR32888, snoRNA:Me28S-A3407a, Me28S-A3407a(U29), snoRNA:U29:54Ea, Me28S-A3407a" - CR32888 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010813 v(3)03699 v(3)03699 http://flybase.org/reports/FBgn0010813 - gene - - - "l(3)03699, v(3)03699" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,recessive" "wing vein,posterior crossvein,tergite" FBgn0262160 CG9932 - http://flybase.org/reports/FBgn0262160 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 chaeta development ; GO:0022416 | inferred from genetic interaction with Chi wing disc development ; GO:0035220 | inferred from genetic interaction with Bx - "CG9932, EP2317, Ef4A, elF-4A" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9932 11-Aug-17 DroID_v2017_08 "Drer\zfp64, Drer\prdm9, Drer\rest, Drer\si:ch211-269m15.3" - Cele\tra-4 "Xtro\znf142, Xtro\znf462" "Mmus\Zfp462, Mmus\Zfp335, Mmus\Zfp64" "Hsap\REST, Hsap\ZNF462, Hsap\ZNF335, Hsap\ZNF142, Hsap\ZFP64" FBgn0019672 mor(1)7 mortality gene (1)7 http://flybase.org/reports/FBgn0019672 - gene - - - mor(1)7 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0014894 anon-10Aa anon-10Aa http://flybase.org/reports/FBgn0014894 - gene - - - anon-10Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267310 CR45746 - http://flybase.org/reports/FBgn0267310 non_protein_coding_gene - - - CR45746 - CR45746 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027125 l(3)IIIb lethal (3) IIIb http://flybase.org/reports/FBgn0027125 - gene - - - l(3)IIIb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001418 l(1)6Db lethal (1) 6Db http://flybase.org/reports/FBgn0001418 - gene - - - "EM24, l(1)EM24, l(1)EC224, l(1)6Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020441 Est-17 Est-17 http://flybase.org/reports/FBgn0020441 - gene carboxylic ester hydrolase activity ; GO:0052689 | traceable author statement - - Est-17 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034406 Jheh3 Juvenile hormone epoxide hydrolase 3 http://flybase.org/reports/FBgn0034406 protein_coding_gene cis-stilbene-oxide hydrolase activity ; GO:0033961 | inferred from electronic annotation with InterPro:IPR016292 - - "CG15106, Jheh3" "IPR000639:Epoxide hydrolase-like, IPR010497:Epoxide hydrolase, N-terminal, IPR016292:Epoxide hydrolase, IPR029058:Alpha/Beta hydrolase fold" CG15106 11-Aug-17 DroID_v2017_08 "Drer\ephx4, Drer\ephx1, Drer\ephx5" Scer\YNR064C "Cele\dct-19, Cele\C32H11.4, Cele\C06B3.7, Cele\Y17D7B.2, Cele\C29F3.7, Cele\K08D8.6, Cele\ZK896.4, Cele\F55G11.2, Cele\F55G11.7, Cele\irg-2, Cele\dod-21, Cele\ceeh-1, Cele\C49G7.10, Cele\ceeh-2, Cele\ZK896.5, Cele\C49G7.7, Cele\K10D11.3, Cele\T05E12.6, Cele\K10D11.7, Cele\K08D8.4, Cele\C32H11.9, Cele\C32H11.3, Cele\K10D11.2, Cele\F55G11.4, Cele\dod-17, Cele\K10D11.4, Cele\K08D8.3, Cele\C32H11.1, Cele\Y17D7B.3, Cele\F55C9.6, Cele\C45B11.6, Cele\K08D8.5, Cele\ZK1037.6, Cele\F55G11.8, Cele\F17C11.11, Cele\C49G7.12, Cele\ZK896.1, Cele\T19C9.8, Cele\F55G11.6, Cele\C45B11.2, Cele\dod-24, Cele\W01A11.1, Cele\K09D9.1, Cele\C49C3.9, Cele\K10D11.6, Cele\K10D11.5, Cele\dod-22, Cele\C06B3.6" Xtro\ephx1 "Mmus\Ephx2, Mmus\Ephx4, Mmus\Ephx3, Mmus\Ephx1" "Hsap\EPHX2, Hsap\EPHX4, Hsap\EPHX1, Hsap\EPHX3" "viable,fertile" FBgn0003110 plk plucked http://flybase.org/reports/FBgn0003110 - gene molecular_function ; GO:0003674 | no biological data available chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available plk - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033982 Cyp317a1 Cyp317a1 http://flybase.org/reports/FBgn0033982 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "317a1, CG17453, Cyp317a1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG17453 11-Aug-17 DroID_v2017_08 "Drer\cyp3c3, Drer\cyp3a65, Drer\cyp3c4, Drer\tbxas1, Drer\cyp3c1, Drer\cyp3c2" Scer\ERG11 "Cele\cyp-13A7, Cele\cyp-13A10, Cele\cyp-13A2, Cele\cyp-13A5, Cele\cyp-13A1, Cele\cyp-43A1, Cele\cyp-25A4, Cele\cyp-25A1, Cele\cyp-25A2, Cele\cyp-13B2, Cele\cyp-25A3, Cele\cyp-13A11, Cele\cyp-13A12, Cele\cyp-13A4, Cele\cyp-44A1, Cele\cyp-25A6, Cele\cyp-13B1, Cele\cyp-13A8, Cele\cyp-13A3, Cele\cyp-13A6" "Xtro\cyp3a5, Xtro\tbxas1, Xtro\LOC100494419, Xtro\cyp3a4" "Mmus\Cyp3a44, Mmus\Cyp3a11, Mmus\Ptgis, Mmus\Cyp3a59, Mmus\Cyp3a13, Mmus\Cyp3a16, Mmus\Cyp3a57, Mmus\Cyp3a41b, Mmus\Cyp3a41a, Mmus\Tbxas1, Mmus\Cyp3a25" "Hsap\CYP3A43, Hsap\TBXAS1, Hsap\PTGIS, Hsap\CYP3A5, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A7, Hsap\CYP3A4" viable FBgn0265908 CR44697 - http://flybase.org/reports/FBgn0265908 non_protein_coding_gene - - - "lincRNA.39, CR44697" - CR44697 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032988 Tif-IA Tif-IA http://flybase.org/reports/FBgn0032988 protein_coding_gene "transcription factor activity, RNA polymerase I transcription factor binding ; GO:0001082 | inferred from sequence or structural similarity with SGD:S000001608 RNA polymerase I core binding ; GO:0001042 | inferred from biological aspect of ancestor with PANTHER:PTN000300504 transcription factor activity, core RNA polymerase I binding ; GO:0001181 | inferred from biological aspect of ancestor with PANTHER:PTN000300504" ribosome biogenesis ; GO:0042254 | inferred from direct assay transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript ; GO:0001180 | inferred from sequence or structural similarity with SGD:S000001608 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript ; GO:0001180 | inferred from biological aspect of ancestor with PANTHER:PTN000300504 female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000300504 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with SGD:S000001608 "TIF-IA, Tif-1A, dTIF-IA, CG5951, CG3278, CG16938, Tif-IA, TIF-1A, TifIA, TIf-IA, Tif-1a, tif1a" IPR007991:RNA polymerase I specific transcription initiation factor RRN3 CG3278 11-Aug-17 DroID_v2017_08 Drer\rrn3 Scer\RRN3 Cele\C36E8.1 Xtro\rrn3 Mmus\Rrn3 Hsap\RRN3 "cell growth defective,somatic clone,developmental rate defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,visible,partially lethal - majority die,some die during pupal stage" "female germline cell,mesothoracic tergum" DRSC03717 IE -1.606059088 0.218455113 -0.348822672 5.758255446 -0.251198359 -0.593740873 FBgn0025169 l(2)38EFb lethal (2) 38EFb http://flybase.org/reports/FBgn0025169 - gene - - - l(2)38EFb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0070050 3L-114-20 3L-114-20 http://flybase.org/reports/FBgn0070050 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3L-114-20 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265450 CR44350 - http://flybase.org/reports/FBgn0265450 non_protein_coding_gene - - - CR44350 - CR44350 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035392 CG1271 - http://flybase.org/reports/FBgn0035392 protein_coding_gene glycerol kinase activity ; GO:0004370 | NOT inferred from key residues glycerol metabolic process ; GO:0006071 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 triglyceride metabolic process ; GO:0006641 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 glycerol-3-phosphate biosynthetic process ; GO:0046167 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 CG1271 "IPR018483:Carbohydrate kinase, FGGY, conserved site, IPR018485:Carbohydrate kinase, FGGY, C-terminal, IPR018484:Carbohydrate kinase, FGGY, N-terminal, IPR000577:Carbohydrate kinase, FGGY" CG1271 11-Aug-17 DroID_v2017_08 "Drer\zgc:172295, Drer\gk5" Scer\GUT1 "Cele\R11F4.1, Cele\C55B6.1" "Xtro\gk, Xtro\gk5" "Mmus\Gk2, Mmus\Gykl1, Mmus\Gk5, Mmus\Shpk, Mmus\Gk" "Hsap\SHPK, Hsap\GK, Hsap\GK2, Hsap\GK5" viable FBgn0042640 fz::fz2 fz::fz2 http://flybase.org/reports/FBgn0042640 engineered_fusion_gene - - - fz::fz2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "planar polarity defective,cell non-autonomous,visible,lethal - all die before end of pupal stage,some die during pupal stage" "wing hair,cell non-autonomous,unguis,wing margin bristle,ectopic,wing,wing margin,mesothoracic tergum,leg,distal,ommatidium" FBgn0267680 CR46016 - http://flybase.org/reports/FBgn0267680 non_protein_coding_gene - - - CR46016 - CR46016 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016868 l(2)39Aa lethal (2) 39Aa http://flybase.org/reports/FBgn0016868 "FBgn0016869, FBgn0016870" gene - - - "l(2)39Ac, l(2)39Ab, l(2)39Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001190 Hg Hang glider http://flybase.org/reports/FBgn0001190 - gene - - - Hg - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0014921 anon-72ABe anon-72ABe http://flybase.org/reports/FBgn0014921 - gene - - - anon-72ABe - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001152 gt-4 giant 4 http://flybase.org/reports/FBgn0001152 - gene - - - "gt-4, gt4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced" FBgn0016023 l(3)87Em lethal (3) 87Em http://flybase.org/reports/FBgn0016023 - gene - - - l(3)87Em - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260367 GSd426 - http://flybase.org/reports/FBgn0260367 gene - - - GSd426 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035900 ZC3H3 ZC3H3 http://flybase.org/reports/FBgn0035900 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000559726 endoribonuclease activity ; GO:0004521 | inferred from biological aspect of ancestor with PANTHER:PTN000559726 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KNF2 inferred from physical interaction with UniProtKB:Q9U1H9 inferred from physical interaction with UniProtKB:Q9VIV2 mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from biological aspect of ancestor with PANTHER:PTN000559727 nuclear export ; GO:0051168 | inferred from mutant phenotype poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from mutant phenotype regulation of mRNA export from nucleus ; GO:0010793 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000559726 "ZC3H3, CG6694, dZC3H3" "IPR000571:Zinc finger, CCCH-type" CG6694 11-Aug-17 DroID_v2017_08 Drer\zc3h3 Scer\YTH1 Cele\cpsf-4 Xtro\zc3h3 Mmus\Zc3h3 "Hsap\CPSF4L, Hsap\ZC3H3" "viable,fertile" DRSC10696 IEK 2.929042558 -0.507586752 2.821172069 -3.08114176 0.270020129 2.495981433 FBgn0051454 CG31454 - http://flybase.org/reports/FBgn0051454 protein_coding_gene molecular_function ; GO:0003674 | no biological data available peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with RGD:1309948 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with RGD:1309948 peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000279123 "CG11740, CG31454" "IPR026749:Transmembrane protein 135, IPR031926:Transmembrane protein 135, N-terminal domain" CG31454 11-Aug-17 DroID_v2017_08 Drer\tmem135 - Cele\tmem-135 Xtro\tmem135 Mmus\Tmem135 Hsap\TMEM135 "viable,fertile" FBgn0266908 CR45368 - http://flybase.org/reports/FBgn0266908 non_protein_coding_gene - - - CR45368 - CR45368 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040346 CG3704 - http://flybase.org/reports/FBgn0040346 protein_coding_gene GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000477654 RNA polymerase II complex import to nucleus ; GO:0044376 | inferred from biological aspect of ancestor with PANTHER:PTN000477655 RNA polymerase III complex localization to nucleus ; GO:1990022 | inferred from biological aspect of ancestor with PANTHER:PTN000477655 - "EG:BACR7A4.17, CG3704, XAB1" "IPR004130:GPN-loop GTPase, IPR030230:GPN-loop GTPase 1, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3704 11-Aug-17 DroID_v2017_08 Drer\gpn1 Scer\NPA3 Cele\gop-2 - Mmus\Gpn1 "Hsap\ZNF512, Hsap\GPN1" "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage" trichogen cell FBgn0021936 l(2)k10825 lethal (2) k10825 http://flybase.org/reports/FBgn0021936 - gene - - - l(2)k10825 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262026 CG42837 - http://flybase.org/reports/FBgn0262026 protein_coding_gene - retrograde axonal transport ; GO:0008090 | inferred from mutant phenotype - "CG42837, CG8446" - CG42837 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011261 Dmnd Dimethylnitrosamine demethylase http://flybase.org/reports/FBgn0011261 - gene dimethylnitrosamine demethylase activity ; GO:0004162 | inferred from direct assay - intracellular membrane-bounded organelle ; GO:0043231 | inferred from direct assay "DMN-d, Dmnd" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260250 GSd219 - http://flybase.org/reports/FBgn0260250 gene - - - GSd219 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0031561 IM33 Immune induced molecule 33 http://flybase.org/reports/FBgn0031561 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 response to bacterium ; GO:0009617 | inferred from expression pattern - "CT37183, BcDNA:RH38008, BcDNA:RH05411, CG16712, IM33, DIM 33" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG16712 11-Aug-17 DroID_v2017_08 "Drer\ambp, Drer\si:dkey-117n7.5, Drer\tfpi2, Drer\spint2, Drer\si:dkeyp-73b11.8, Drer\tfpia, Drer\spint1b, Drer\spint1a, Drer\col6a4a" - "Cele\T22F7.3, Cele\ZC84.6, Cele\Y49G5A.1, Cele\F30H5.3, Cele\ZC84.1, Cele\R12A1.3, Cele\Y55F3BR.2, Cele\C02F12.5" "Xtro\tfpi2, Xtro\spint2, Xtro\ambp, Xtro\spint1" "Mmus\Eppin, Mmus\Wfdc6a, Mmus\Spint2, Mmus\Spint3, Mmus\Spint1, Mmus\Tfpi, Mmus\Tfpi2, Mmus\Wfdc8, Mmus\Spint5, Mmus\Spint4, Mmus\Wfdc6b, Mmus\Wfikkn2, Mmus\Ambp" "Hsap\EPPIN-WFDC6, Hsap\SLPI, Hsap\SPINT4, Hsap\WFDC6, Hsap\TFPI2, Hsap\SPINT2, Hsap\WFIKKN2, Hsap\SPINT3, Hsap\WFIKKN1, Hsap\TFPI, Hsap\WFDC8, Hsap\SPINT1, Hsap\AMBP" viable DRSC24513 K -0.116440151 0.182557992 0.308400543 0.533289974 0.371570296 -2.090654865 FBgn0053667 CG33667 - http://flybase.org/reports/FBgn0053667 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33667 - CG33667 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039953 CG17668 - http://flybase.org/reports/FBgn0039953 protein_coding_gene - - - CG17668 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029826 CG6041 - http://flybase.org/reports/FBgn0029826 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP86, CG6041" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG6041 11-Aug-17 DroID_v2017_08 "Drer\st14b, Drer\si:ch211-165b19.8" - "Cele\svh-1, Cele\try-1" Xtro\gzmh "Mmus\Prss55, Mmus\Cfd" "Hsap\KLK10, Hsap\PRSS55, Hsap\AZU1, Hsap\CFD" viable FBgn0037931 CG18476 - http://flybase.org/reports/FBgn0037931 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG18476, CG17822" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG18476 11-Aug-17 DroID_v2017_08 "Drer\znf1015, Drer\znf142, Drer\znf1032, Drer\ikzf5, Drer\znf1007, Drer\prdm5, Drer\znf648, Drer\si:dkeyp-68b7.7, Drer\znf408, Drer\si:ch211-261d7.6, Drer\prdm1a, Drer\znf989, Drer\znf1034, Drer\znf1124, Drer\si:zfos-1425h8.1, Drer\zgc:165515, Drer\si:ch211-119o8.6, Drer\znf1023, Drer\LOC100534814, Drer\znf1059, Drer\si:dkey-15h8.16, Drer\znf1035, Drer\ikzf1, Drer\znf1003, Drer\si:dkey-166n8.9, Drer\si:dkey-253d23.2, Drer\znf1002, Drer\LOC100332930, Drer\znf1004, Drer\zgc:66448, Drer\znf1001, Drer\si:ch211-266d19.4, Drer\LOC100332443, Drer\znf1005, Drer\znf1014" Scer\PZF1 "Cele\egl-43, Cele\eor-1, Cele\Y48G8AL.10, Cele\Y55F3AM.14, Cele\M03D4.4, Cele\Y111B2A.10, Cele\pag-3, Cele\blmp-1" "Xtro\ikzf3, Xtro\zbtb47, Xtro\ikzf2, Xtro\ikzf1, Xtro\ikzf4, Xtro\znf668, Xtro\znf142, Xtro\prdm5" "Mmus\Zfp945, Mmus\Zfp418, Mmus\Prdm16, Mmus\Zfp40, Mmus\Ikzf4, Mmus\Zfp142, Mmus\Zfp189, Mmus\Zbtb41, Mmus\Ikzf5, Mmus\Gm13212, Mmus\Zfp619, Mmus\Zfp768, Mmus\Zfp74, Mmus\Zfp663, Mmus\Zfp648, Mmus\Zfp11, Mmus\Zfp26, Mmus\Prdm9, Mmus\Ikzf2, Mmus\Ikzf3, Mmus\Ikzf1, Mmus\Zfp62, Mmus\Zfp27, Mmus\Zfp808, Mmus\Zfp473, Mmus\Zkscan5, Mmus\Zfp748, Mmus\Zfp628, Mmus\Zfp317, Mmus\Zfp729a, Mmus\Gm14124" "Hsap\ZNF628, Hsap\ZNF254, Hsap\ZNF169, Hsap\IKZF3, Hsap\ZNF721, Hsap\ZNF568, Hsap\ZNF658, Hsap\ZNF717, Hsap\PRDM1, Hsap\PRDM16, Hsap\ZNF274, Hsap\ZNF408, Hsap\ZNF624, Hsap\ZNF394, Hsap\ZKSCAN7, Hsap\ZNF133, Hsap\RBAK-RBAKDN, Hsap\ZNF208, Hsap\PRDM9, Hsap\IKZF1, Hsap\IKZF5, Hsap\ZFP62, Hsap\ZNF57, Hsap\PRDM5, Hsap\ZNF33B, Hsap\ZNF850, Hsap\ZNF808, Hsap\HKR1, Hsap\ZNF33A, Hsap\ZKSCAN5, Hsap\ZNF585A, Hsap\ZNF599, Hsap\ZNF160, Hsap\IKZF4, Hsap\IKZF2, Hsap\ZNF485, Hsap\ZBTB41, Hsap\ZNF594, Hsap\ZNF648, Hsap\ZNF585B, Hsap\ZNF343, Hsap\ZNF142" viable FBgn0002487 l(3)SG47 lethal (3) SG47 http://flybase.org/reports/FBgn0002487 - gene - - - l(3)SG47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0043033 l(2)42Cb lethal (2) 42Cb http://flybase.org/reports/FBgn0043033 gene - - - l(2)42Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264490 Eip93F Ecdysone-induced protein 93F http://flybase.org/reports/FBgn0264490 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" "cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype hormone-mediated apoptotic signaling pathway ; GO:0008628 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern autophagic cell death ; GO:0048102 | traceable author statement phagocytosis, engulfment ; GO:0006911 | traceable author statement salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern" nucleus ; GO:0005634 | non-traceable author statement polytene chromosome ; GO:0005700 | traceable author statement polytene chromosome ; GO:0005700 | non-traceable author statement transcriptionally active chromatin ; GO:0035327 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "Eip93F, psg11, CG18389, E93, Eip93f, l(3)ry93, eip93f, anon-WO02059370.58, l(3)93, Eip93, lincRNA.833" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR007889:DNA binding HTH domain, Psq-type, IPR009057:Homeobox domain-like" CG18389 11-Aug-17 DroID_v2017_08 "Drer\wu:fc17b08, Drer\lcorl" - Cele\mbr-1 - "Mmus\Lcor, Mmus\Lcorl" "Hsap\LCORL, Hsap\LCOR" " prepupal stage | early , prepupal stage | late , prepupal stage | stage P1--pupal stage | stage P7 , prepupal stage | 12 hr , pupal stage | 196 hr " " pupal/adult digestive system

, imaginal disc

, embryonic/larval salivary gland

, embryonic/larval fat body

, organism

, larval central nervous system

" FBgn0042634 l(3)S099801b lethal (3) S099801b http://flybase.org/reports/FBgn0042634 gene - - - "l(3)099801, 0998/01, l(3)S099801, l(3)S099801b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0262781 Su(E1)-O - http://flybase.org/reports/FBgn0262781 gene - - - Su(E1)-O - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029647 CG17959 - http://flybase.org/reports/FBgn0029647 protein_coding_gene - - - CG17959 - CG17959 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263882 l(3)C10 - http://flybase.org/reports/FBgn0263882 gene - - - l(3)C10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0010038 GstD2 Glutathione S transferase D2 http://flybase.org/reports/FBgn0010038 FBgn0038021 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione peroxidase activity ; GO:0004602 | traceable author statement glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GstD21, gstD21, DmGSTD2, DmGST21, Gst, CG4181, GST, GstD2, GSTD2, GST-D2, GST D2, gstd2, gstd21, gst D21, Gstd21, gstD2" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG4181 11-Aug-17 DroID_v2017_08 "Drer\gstt2, Drer\gstt1b, Drer\eef1g, Drer\eef1e1, Drer\gstr, Drer\vars, Drer\gstt1a, Drer\mars" "Scer\YGR201C, Scer\TEF4, Scer\CAM1, Scer\GTT2, Scer\URE2, Scer\GTT1" - "Xtro\eef1e1, Xtro\eef1g, Xtro\gstt1" "Mmus\Gstt2, Mmus\Eef1g, Mmus\Eef1e1, Mmus\Gstt3, Mmus\Gstt1, Mmus\Mars, Mmus\Gstt4, Mmus\Vars" "Hsap\VARS, Hsap\MARS, Hsap\GSTT2B, Hsap\GSTT2, Hsap\EEF1E1, Hsap\EEF1G, Hsap\GSTT1" adult stage "viable,fertile" FBgn0052634 CG32634 - http://flybase.org/reports/FBgn0052634 protein_coding_gene - - - "BcDNA:GM08788, CG32634" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016771 anon-59Da anon-59Da http://flybase.org/reports/FBgn0016771 - gene - - - anon-59Da - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260573 MENE-LL7 - http://flybase.org/reports/FBgn0260573 gene - - - MENE-LL7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye disc,somatic clone" FBgn0042144 CG18821 - http://flybase.org/reports/FBgn0042144 protein_coding_gene - - - CG18821 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0070054 2L-250-35 2L-250-35 http://flybase.org/reports/FBgn0070054 gene molecular_function ; GO:0003674 | no biological data available blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 2L-250-35 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic segment,germline clone,maternal effect" FBgn0259557 B0457 - http://flybase.org/reports/FBgn0259557 gene - - - B0457 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262900 CG43255 - http://flybase.org/reports/FBgn0262900 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43255 - CG43255 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004397 Vinc Vinculin http://flybase.org/reports/FBgn0004397 "FBgn0015840, FBgn0024918" protein_coding_gene actin filament binding ; GO:0051015 | inferred from electronic annotation with InterPro:IPR006077 structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR000633 actin binding ; GO:0003779 | inferred from sequence or structural similarity "cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR000633, InterPro:IPR006077 phagocytosis ; GO:0006909 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity" actin cytoskeleton ; GO:0015629 | inferred from electronic annotation with InterPro:IPR000633 focal adhesion ; GO:0005925 | inferred from sequence or structural similarity "vinc, EG:103B4.1, CT11081, CG3299, Dmvincp, Vin2EF, Vin, Vinc, VINC" "IPR000633:Vinculin, conserved site, IPR006077:Vinculin/alpha-catenin" CG3299 11-Aug-17 DroID_v2017_08 "Drer\vclb, Drer\ctnnal1, Drer\vcla, Drer\ctnna1, Drer\ctnna2" - Cele\deb-1 "Xtro\vcl, Xtro\ctnnal1, Xtro\ctnna1" "Mmus\Ctnna2, Mmus\Ctnna1, Mmus\Vcl, Mmus\Ctnna3, Mmus\Ctnnal1, Mmus\Gm14025" "Hsap\CTNNA1, Hsap\CTNNA2, Hsap\CTNNAL1, Hsap\VCL, Hsap\CTNNA3" "viable,fertile" muscle attachment site FBgn0069331 X-100-6 X-100-6 http://flybase.org/reports/FBgn0069331 gene molecular_function ; GO:0003674 | no biological data available segment polarity determination ; GO:0007367 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-100-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,recessive,rescuable maternal effect,some die during embryonic stage,maternal effect" "embryonic segment,germline clone,maternal effect,denticle belt,ectopic" FBgn0266139 CR44845 - http://flybase.org/reports/FBgn0266139 non_protein_coding_gene - - - CR44845 - CR44845 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033616 CG7745 - http://flybase.org/reports/FBgn0033616 protein_coding_gene - - - "CG7745, CC8" IPR006578:MADF domain CG7745 11-Aug-17 DroID_v2017_08 "Drer\zgc:152938, Drer\si:ch211-207i20.3, Drer\LOC100330838" - "Cele\madf-4, Cele\madf-9, Cele\madf-10, Cele\madf-3, Cele\madf-8, Cele\madf-2, Cele\madf-5" - - - viable FBgn0030694 CG15602 - http://flybase.org/reports/FBgn0030694 protein_coding_gene - - - CG15602 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR017455:Zinc finger, FYVE-related, IPR011011:Zinc finger, FYVE/PHD-type" CG15602 11-Aug-17 DroID_v2017_08 Drer\zfyve19 - Cele\R11D1.10 Xtro\zfyve19 Mmus\Zfyve19 Hsap\ZFYVE19 viable DRSC19671 K 0.056750037 -0.073950304 0.951909215 -0.134260156 2.473247619 0.572435689 FBgn0039972 CG17018 - http://flybase.org/reports/FBgn0039972 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 regulation of gene expression ; GO:0010468 | inferred from electronic annotation with InterPro:IPR024768 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:29562 "CG17410, BcDNA:RE40762, CG17018" "IPR025605:OST-HTH/LOTUS domain, IPR024768:Meiosis arrest female protein 1, IPR000504:RNA recognition motif domain, IPR034191:Marf1, RNA recognition motif 2" CG17018 11-Aug-17 DroID_v2017_08 - - - Xtro\kiaa0430 Mmus\Marf1 Hsap\KIAA0430 viable FBgn0028941 CG16853 - http://flybase.org/reports/FBgn0028941 protein_coding_gene - - - "BG:BACR48E02.3, CG16853" - CG16853 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266705 CR45195 - http://flybase.org/reports/FBgn0266705 non_protein_coding_gene - - - CR45195 - CR45195 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050398 CG30398 - http://flybase.org/reports/FBgn0050398 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30398 "IPR007330:MIT, IPR032341:MIT, C-terminal phospholipase D-like domain" CG30398 11-Aug-17 DroID_v2017_08 Drer\mitd1 - Cele\Y66D12A.10 Xtro\mitd1 Mmus\Mitd1 Hsap\MITD1 viable FBgn0065360 l(2)SH1749 lethal (2) SH1749 http://flybase.org/reports/FBgn0065360 gene - - - "l(2)SH1749, l(2)SH2 1749" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031015 CG14197 - http://flybase.org/reports/FBgn0031015 protein_coding_gene - - - CG14197 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004543 l(4)102CDn lethal (4) 102CDn http://flybase.org/reports/FBgn0004543 - gene - - - "l(4)CDn, l(4)28, l(4)102CDn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0036662 CG9706 - http://flybase.org/reports/FBgn0036662 protein_coding_gene acetyl-CoA transporter activity ; GO:0008521 | inferred from electronic annotation with InterPro:IPR024371 solute:proton symporter activity ; GO:0015295 | inferred from biological aspect of ancestor with PANTHER:PTN000299690 transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000299690 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000299690 CG9706 "IPR020846:Major facilitator superfamily domain, IPR024371:Acetyl-coenzyme A transporter 1" CG9706 11-Aug-17 DroID_v2017_08 "Drer\slc33a1, Drer\si:dkey-229d2.4" "Scer\YBR220C, Scer\YBR219C" Cele\T26C5.3 Xtro\slc33a1 "Mmus\Mfsd3, Mmus\Slc33a1" "Hsap\SLC33A1, Hsap\MFSD3" "partially lethal - majority die,some die during pupal stage" FBgn0028596 l(2)k07521 lethal (2) k07521 http://flybase.org/reports/FBgn0028596 gene - - - l(2)k07521 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035663 CG6462 - http://flybase.org/reports/FBgn0035663 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG6462, SP127" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG6462 11-Aug-17 DroID_v2017_08 "Drer\f7, Drer\masp2, Drer\f10, Drer\plg, Drer\f2, Drer\habp2, Drer\plaua, Drer\mst1, Drer\f9b, Drer\st14b" - - "Xtro\mst1, Xtro\prss12, Xtro\f2, Xtro\f10, Xtro\st14, Xtro\habp2, Xtro\plat, Xtro\proc" "Mmus\Plau, Mmus\Tmprss6, Mmus\Prss12, Mmus\Plg, Mmus\Hgfac, Mmus\Habp2, Mmus\St14, Mmus\Plat, Mmus\F10, Mmus\Mst1, Mmus\Tmprss9, Mmus\C1s2, Mmus\Hgf, Mmus\F2, Mmus\F7, Mmus\F12, Mmus\C1s1, Mmus\Hp" "Hsap\TMPRSS11E, Hsap\HGFAC, Hsap\MST1L, Hsap\TMPRSS6, Hsap\PLG, Hsap\F9, Hsap\HGF, Hsap\PLAT, Hsap\PRSS12, Hsap\PLAU, Hsap\F2, Hsap\ST14, Hsap\F10, Hsap\MASP1, Hsap\F12, Hsap\HABP2, Hsap\MST1" viable FBgn0263526 mir-4971 mir-4971 stem loop http://flybase.org/reports/FBgn0263526 miRNA_gene - - - "mir-4971, dme-mir-4971, CR43511" - CR43511 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002902 mus305 mutagen-sensitive 305 http://flybase.org/reports/FBgn0002902 - gene - - - "mus(3)305, mus305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive,recessive,radiation sensitive" FBgn0013392 anon-1Bc anon-1Bc http://flybase.org/reports/FBgn0013392 - gene - - - "T9, anon-1Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , pupal stage " FBgn0001738 l(1)HM8 lethal (1) HM8 http://flybase.org/reports/FBgn0001738 - gene - - - l(1)HM8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,visible,female fertile" wing FBgn0024702 bcd::RpLP2 bcd::RpLP2 http://flybase.org/reports/FBgn0024702 - engineered_fusion_gene - - - "bcd::RpP1, bcd::RpLP2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066329 rigel rigel http://flybase.org/reports/FBgn0066329 gene - - - "rig, rigel" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022037 l(2)k08504 lethal (2) k08504 http://flybase.net/reports/FBgn0022037.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0041600 gav gav http://flybase.org/reports/FBgn0041600 gene - - - gav - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034688 CG11474 - http://flybase.org/reports/FBgn0034688 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11474 IPR002791:Domain of unknown function DUF89 CG11474 11-Aug-17 DroID_v2017_08 Drer\armt1 Scer\YMR027W Cele\F31D4.2 Xtro\armt1 Mmus\Armt1 Hsap\ARMT1 viable FBgn0037576 Or85a Odorant receptor 85a http://flybase.org/reports/FBgn0037576 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "85a, DOR31, 85A.4, CG7454, Or85a, DmOR85A, or85a" "IPR004117:Olfactory receptor, insect" CG7454 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" chaeta FBgn0044396 Scim32 Sensitized chromosome inheritance modifier 32 http://flybase.org/reports/FBgn0044396 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0027154 l(3)3a lethal (3) 3a http://flybase.org/reports/FBgn0027154 - gene - - - l(3)3a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265796 CR44585 - http://flybase.org/reports/FBgn0265796 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR44585 - CR44585 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036482 CG13457 - http://flybase.org/reports/FBgn0036482 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT16542, BcDNA:AT15860, CG13457" - CG13457 11-Aug-17 DroID_v2017_08 Drer\rnps1 - - Xtro\rnps1 Mmus\Rnps1 Hsap\RNPS1 viable FBgn0051797 CG31797 - http://flybase.org/reports/FBgn0051797 protein_coding_gene - - - "CT35089, CG15176, CG15175, CG31797" - CG31797 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083037 snoRNA:Psi18S-525b snoRNA:Psi18S-525b http://flybase.org/reports/FBgn0083037 snoRNA_gene - - - "snoRNA:Psi18S-525b, psi18S-525b, CR34572" - CR34572 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033079 Fmo-2 Flavin-containing monooxygenase 2 http://flybase.org/reports/FBgn0033079 protein_coding_gene "N,N-dimethylaniline monooxygenase activity ; GO:0004499 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946 NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946 monooxygenase activity ; GO:0004497 | inferred from direct assay" oxidation-reduction process ; GO:0055114 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "DmFMO-2, CG3174, Fmo-2, fmo2" "IPR000960:Flavin monooxygenase FMO, IPR020946:Flavin monooxygenase-like, IPR023753:FAD/NAD(P)-binding domain" CG3174 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-239i20.2, Drer\LOC793236, Drer\si:dkey-239i20.4, Drer\fmo5, Drer\zgc:77439, Drer\foxred2" Scer\FMO1 "Cele\C01H6.4, Cele\fmo-3, Cele\fmo-1, Cele\fmo-4, Cele\C46H11.2, Cele\fmo-2, Cele\fmo-5" "Xtro\foxred2, Xtro\fmo1, Xtro\fmo2, Xtro\fmo5, Xtro\fmo3" "Mmus\Gm4846, Mmus\Foxred2, Mmus\Fmo2, Mmus\Fmo3, Mmus\Fmo4, Mmus\Fmo5, Mmus\Fmo9, Mmus\Fmo1, Mmus\Fmo6, Mmus\Gm4847" "Hsap\FMO3, Hsap\FOXRED2, Hsap\FMO1, Hsap\FMO2, Hsap\FMO4, Hsap\FMO5" viable FBgn0040608 CG14246 - http://flybase.org/reports/FBgn0040608 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG32950, CG14246" IPR002557:Chitin binding domain CG14246 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014285 l(3)64Ad lethal (3) 64Ad http://flybase.org/reports/FBgn0014285 - gene - - - l(3)64Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016725 Roa Rough anteriorly http://flybase.org/reports/FBgn0016725 - gene molecular_function ; GO:0003674 | no biological data available compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Roa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ommatidium,interommatidial bristle,pigment cell" FBgn0063899 Rst(2)At Resistance to Asobara tabida http://flybase.org/reports/FBgn0063899 gene - - - "Rat, Rst(2)At" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259707 CG42361 - http://flybase.org/reports/FBgn0259707 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42361, CG3579" IPR009218:Predicted HD phosphohydrolase CG42361 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262440 mir-280 mir-280 stem loop http://flybase.org/reports/FBgn0262440 miRNA_gene - - - "mir-280, CR43002, miR-280, CR33591, dme-miR-280" - CR43002 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0063406 l(3)CG1 lethal (3) CG1 http://flybase.org/reports/FBgn0063406 gene - - - l(3)CG1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264993 CR44144 - http://flybase.org/reports/FBgn0264993 non_protein_coding_gene - - - CR44144 - CR44144 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031874 CG13775 - http://flybase.org/reports/FBgn0031874 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR008906 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001512074 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001512074" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001512074 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001512074 CG13775 "IPR003656:Zinc finger, BED-type, IPR008906:HAT, C-terminal dimerisation domain, IPR013087:Zinc finger C2H2-type, IPR012337:Ribonuclease H-like domain" CG13775 11-Aug-17 DroID_v2017_08 "Drer\zbed4, Drer\si:dkey-13n23.3, Drer\LOC108179061, Drer\si:dkey-93n13.2, Drer\si:dkeyp-117b8.4, Drer\zgc:161969, Drer\si:dkey-109j17.5, Drer\mybl2a, Drer\si:ch211-152f22.4" - "Cele\gei-13, Cele\bed-3, Cele\B0545.4, Cele\ZK1098.2, Cele\ets-6, Cele\bed-1, Cele\C10A4.1, Cele\F46F2.4, Cele\Y105C5A.15, Cele\ZK662.5, Cele\F19F10.11, Cele\gon-14, Cele\K09A11.1, Cele\C53D6.6, Cele\Y67D8C.3, Cele\C09E7.4, Cele\dpy-20" "Xtro\zbed4, Xtro\LOC105945140" "Mmus\Zbed6, Mmus\Zbed4" "Hsap\ZBED6, Hsap\ZBED6CL, Hsap\ZBED1, Hsap\DHRSX, Hsap\ZBED4" embryonic/larval hemocyte | third instar larval stage FBgn0265829 CR44618 - http://flybase.org/reports/FBgn0265829 non_protein_coding_gene - - - "lincRNA.98, CR44618" - CR44618 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004224 l(3)84Fl lethal (3) 84Fl http://flybase.org/reports/FBgn0004224 - gene - - - l(3)84Fl - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002644 man mandarin http://flybase.org/reports/FBgn0002644 - gene - - - man - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective" pigment cell FBgn0046258 CG12880 - http://flybase.org/reports/FBgn0046258 protein_coding_gene - - - "BEST:LD29228, CG12880" IPR031983:Protein of unknown function DUF4786 CG12880 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,planar polarity defective" trichogen cell FBgn0022359 Sodh-2 Sorbitol dehydrogenase-2 http://flybase.org/reports/FBgn0022359 - protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR002328, InterPro:IPR020843 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR002328" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR002328, InterPro:IPR013149, InterPro:IPR013154" - "DM_7299382, Sdh, Sdh-2, SODH-2, CG4649, Sodh-2" "IPR002328:Alcohol dehydrogenase, zinc-type, conserved site, IPR011032:GroES-like, IPR013149:Alcohol dehydrogenase, C-terminal, IPR013154:Alcohol dehydrogenase, N-terminal, IPR016040:NAD(P)-binding domain, IPR020843:Polyketide synthase, enoylreductase domain" CG4649 11-Aug-17 DroID_v2017_08 "Drer\sord, Drer\c2h1orf27" "Scer\BDH2, Scer\SOR1, Scer\BDH1, Scer\XYL2, Scer\SOR2" "Cele\R04B5.5, Cele\D2063.1, Cele\R04B5.6" Xtro\sord Mmus\Sord Hsap\SORD " larval stage , adult stage , pupal stage " viable FBgn0065479 l(2)SH1295 lethal (2) SH1295 http://flybase.org/reports/FBgn0065479 gene - - - "l(2)SH1295, l(2)SH2 1295" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014339 lphB larval photokinesis B http://flybase.org/reports/FBgn0014339 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available lphB - - 11-Aug-17 DroID_v2017_08 - - - - - - visual behavior defective FBgn0025633 CG13366 - http://flybase.org/reports/FBgn0025633 - protein_coding_gene - wing disc development ; GO:0035220 | inferred from mutant phenotype proboscis morphogenesis ; GO:0048734 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype notum morphogenesis ; GO:0048802 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern - "AAD55419, EG:118B3.2, CG13366" IPR001715:Calponin homology domain CG13366 11-Aug-17 DroID_v2017_08 "Drer\smtna, Drer\smtnl, Drer\si:ch211-195o20.7, Drer\specc1, Drer\specc1lb, Drer\specc1la, Drer\smtnl1, Drer\smtnb" - "Cele\F26F4.5, Cele\M151.4, Cele\T15B12.1" "Xtro\tpr, Xtro\smtn, Xtro\specc1l" "Mmus\Specc1, Mmus\Smtn, Mmus\Smtnl2, Mmus\Specc1l, Mmus\Smtnl1" "Hsap\SPECC1, Hsap\SMTNL1, Hsap\SMTNL2, Hsap\SPECC1L, Hsap\GOLGA2, Hsap\ADORA2A, Hsap\SMTN" "viable,sterile,flightless,partially lethal - majority die,some die during pharate adult stage" "indirect flight muscle,sarcomereMef2.PR,wing,proboscis,mesothoracic tergum" FBgn0010714 l(3)00281 lethal (3) 00281 http://flybase.org/reports/FBgn0010714 - gene molecular_function ; GO:0003674 | no biological data available regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(3)00281 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect,poor" "embryonic/first instar larval cuticle,dorsal,maternal effect,head" FBgn0011089 l(1)Q49 lethal (1) Q49 http://flybase.org/reports/FBgn0011089 FBgn0010210 gene - - - l(1)Q49 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002382 l(3)93Cb lethal (3) 93Cb http://flybase.org/reports/FBgn0002382 - gene - - - "er5, l(3)er5, l(3)93Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028347 l(1)G0182 lethal (1) G0182 http://flybase.org/reports/FBgn0028347 gene - - - l(1)G0182 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0024293 Spn43Ab Serpin 43Ab http://flybase.org/reports/FBgn0024293 "FBgn0033146, FBgn0063808" protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG1865, Ser2, SER2, anon-WO0118057.2, Spn43Ab, spn43Ab" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG1865 11-Aug-17 DroID_v2017_08 "Drer\zgc:174259, Drer\serpinb1, Drer\serpinb1l3, Drer\serpinb5l, Drer\serpine3, Drer\serpina1l, Drer\serpinb1l2, Drer\si:ch1073-416d2.3, Drer\serpini1, Drer\zgc:173729, Drer\si:ch211-186e20.7, Drer\serpinc1, Drer\serpine2, Drer\serpinb1l4, Drer\serpinf2b, Drer\serpine1, Drer\serpinh1b, Drer\serpind1, Drer\serping1, Drer\serpinh1a, Drer\agt, Drer\serpinf1, Drer\serpinf2a, Drer\serpina7" - "Cele\srp-8, Cele\srp-2, Cele\C28G1.2, Cele\srp-7, Cele\srp-3, Cele\srp-6, Cele\srp-1" "Xtro\serpinb4, Xtro\serpina3k, Xtro\serpina3m, Xtro\serpina10, Xtro\serpine1, Xtro\serpinc1, Xtro\serpina3, Xtro\serpine2, Xtro\serpini2, Xtro\serpinb11, Xtro\serpina1, Xtro\serpind1, Xtro\serpini1, Xtro\serpinb1, Xtro\serpinb6, Xtro\serpinb5" "Mmus\Serpinf2, Mmus\Serpinb9b, Mmus\Serpine2, Mmus\Serpina1a, Mmus\Serpina1b, Mmus\Serpinb9c, Mmus\Serpina1e, Mmus\Serpina3k, Mmus\Serpina6, Mmus\Serpinb1b, Mmus\Agt, Mmus\Gm11397, Mmus\Serpina3f, Mmus\Serpinb6b, Mmus\Serpina10, Mmus\Serpind1, Mmus\Serpina3g, Mmus\Serpina3n, Mmus\Serpinb11, Mmus\Serpinb8, Mmus\Serpinb6a, Mmus\Serpine3, Mmus\Serpinb9e, Mmus\Serpini1, Mmus\Serpina7, Mmus\Serpina1d, Mmus\Serpinb9, Mmus\Serpinb9f, Mmus\Serpina3a, Mmus\Serpinb6d, Mmus\Serpinb1a, Mmus\Serpinb3a, Mmus\Serpinb6c, Mmus\Serpinb13, Mmus\Serpina12, Mmus\Serpinb7, Mmus\Serpinb1c, Mmus\Serpinb5, Mmus\Serpine1, Mmus\Serpina3i, Mmus\Serpinb2, Mmus\Serpina16, Mmus\Serpinb3d, Mmus\Serpina3j, Mmus\Serpinb9g, Mmus\Serpina3c, Mmus\Serpina1f, Mmus\Serpinb12, Mmus\Serpini2, Mmus\Serpina11, Mmus\Serpinf1, Mmus\Serpinc1, Mmus\Serpinb3c, Mmus\Serpina9, Mmus\Serpina1c, Mmus\Serpinb9d, Mmus\Serpina5, Mmus\Serpinb3b, Mmus\Serpinb6e" "Hsap\SERPINA3, Hsap\SERPINE3, Hsap\SERPINE1, Hsap\SERPINB7, Hsap\SERPINB4, Hsap\SERPINE2, Hsap\SERPINA5, Hsap\HMSD, Hsap\SERPINF1, Hsap\SERPINA6, Hsap\SERPINB2, Hsap\SERPINA4, Hsap\SERPINB9, Hsap\SERPINF2, Hsap\SERPINB12, Hsap\SERPINI2, Hsap\SERPINB11, Hsap\SERPINB1, Hsap\SERPINA11, Hsap\SERPINB13, Hsap\SERPINI1, Hsap\SERPIND1, Hsap\SERPINB5, Hsap\SERPINA10, Hsap\SERPINA12, Hsap\SERPINA7, Hsap\SERPINB6, Hsap\SERPINC1, Hsap\SERPINA9, Hsap\SERPINB3, Hsap\SERPINB8, Hsap\AGT, Hsap\SERPINA1, Hsap\SERPINB10" "partially lethal - majority die,some die during pupal stage" FBgn0261952 srw shrew http://flybase.org/reports/FBgn0261952 protein_coding_gene - positive regulation of decapentaplegic signaling pathway ; GO:0090098 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype amnioserosa formation ; GO:0007378 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from direct assay - "srw, shrew, CG11582" IPR006761:Twisted gastrulation (Tsg) protein CG11582 11-Aug-17 DroID_v2017_08 "Drer\twsg1b, Drer\twsg1a" - Cele\fbxa-74 "Xtro\twsg2, Xtro\twsg1" Mmus\Twsg1 Hsap\TWSG1 FBgn0283682 Ge-1 Ge-1 http://flybase.org/reports/FBgn0283682 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q5U127 inferred from physical interaction with UniProtKB:Q9W1H5 cytoplasmic mRNA processing body assembly ; GO:0033962 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from genetic interaction with me31B defense response to fungus ; GO:0050832 | inferred from mutant phenotype cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay "EDC4, ref(2)M, Ge-1, Ref(2)Me, CG6181, dGe-1, GE-1" "IPR032401:Enhancer of mRNA-decapping protein 4, WD40 repeat region, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG6181 11-Aug-17 DroID_v2017_08 Drer\edc4 - Cele\Y44E3A.6 Xtro\edc4 Mmus\Edc4 Hsap\EDC4 FBgn0016122 Acer Angiotensin-converting enzyme-related http://flybase.org/reports/FBgn0016122 FBgn0022076 protein_coding_gene peptidyl-dipeptidase activity ; GO:0008241 | inferred from sequence or structural similarity with Ance metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity with MGI:MGI:87874 zinc ion binding ; GO:0008270 | inferred from sequence model peptidyl-dipeptidase activity ; GO:0008241 | non-traceable author statement peptidyl-dipeptidase activity ; GO:0008241 | inferred from direct assay "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001548 regulation of heart rate ; GO:0002027 | inferred from mutant phenotype proteolysis ; GO:0006508 | traceable author statement heart development ; GO:0007507 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern heart development ; GO:0007507 | NOT inferred from mutant phenotype positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype heart morphogenesis ; GO:0003007 | inferred from mutant phenotype" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001548 extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "ACER, ACE, l(2)k07704, CG10593, Acer, acer" "IPR001548:Peptidase M2, peptidyl-dipeptidase A" CG10593 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-194e6.1, Drer\ace2, Drer\ace" - Cele\acn-1 "Xtro\ace, Xtro\tmem27, Xtro\ace2" "Mmus\Tmem27, Mmus\Ace, Mmus\Ace3, Mmus\Ace2" "Hsap\ACE2, Hsap\TMEM27, Hsap\ACE" " embryonic stage | stage 14-15 , embryonic stage&&larval stage&&adult stage " embryonic/larval dorsal vessel

"viable,fertile,circadian behavior defective,sleep defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,short lived" "heart primordium,adult heart chamber" FBgn0002132 l(2)K207 lethal (2) K207 http://flybase.org/reports/FBgn0002132 - gene - - - l(2)K207 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0019694 l(3)68Fg lethal (3) 68Fg http://flybase.org/reports/FBgn0019694 - gene - - - "l(3)68Fa, l(3)68Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0027841 CstF64 Cleavage stimulation factor 64 kD subunit http://flybase.org/reports/FBgn0027841 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000566843 mRNA polyadenylation ; GO:0006378 | inferred from electronic annotation with InterPro:IPR033105 pre-mRNA cleavage required for polyadenylation ; GO:0098789 | inferred from biological aspect of ancestor with PANTHER:PTN000566843 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA cleavage stimulating factor complex ; GO:0005848 | inferred from direct assay mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000566843 "CG7697, CStF 64, CstF64, CstF 64, dCstF64, CstF-64" "IPR025742:Cleavage stimulation factor subunit 2, hinge domain, IPR000504:RNA recognition motif domain, IPR033105:Cleavage stimulation factor subunit 2, IPR026896:Transcription termination and cleavage factor, C-terminal domain" CG7697 11-Aug-17 DroID_v2017_08 Drer\cstf2 "Scer\PUB1, Scer\YGR250C, Scer\PTI1, Scer\RNA15, Scer\PIN4" "Cele\R09B3.3, Cele\cpf-2, Cele\R06C1.4" Xtro\cstf2 "Mmus\Cstf2, Mmus\Cstf2t" "Hsap\CSTF2T, Hsap\CSTF2" embryonic stage -- adult stage "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC29486 K 0.038131594 1.094356806 -0.813179488 1.081138392 1.885097034 0.557258589 FBgn0050069 CG30069 - http://flybase.org/reports/FBgn0050069 protein_coding_gene molecular_function ; GO:0003674 | no biological data available wing disc development ; GO:0035220 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "CG8381, CG13017, CG30069" - CG30069 11-Aug-17 DroID_v2017_08 "Drer\ahnak, Drer\txn, Drer\zgc:56493" Scer\RPO21 Cele\trx-4 "Xtro\txn, Xtro\LOC100170420, Xtro\prx, Xtro\ahnak" "Mmus\Ahnak, Mmus\Txndc8, Mmus\Txn1, Mmus\Polr2a, Mmus\Ahnak2, Mmus\Txndc2" "Hsap\TXNDC8, Hsap\AHNAK, Hsap\TXNDC2, Hsap\AHNAK2, Hsap\TXN" "lethal,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" wing FBgn0023127 anon-10Abb anon-10Abb http://flybase.org/reports/FBgn0023127 - gene - - - "21, anon-10Abb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026607 Act57B::Act88F Act57B::Act88F http://flybase.org/reports/FBgn0026607 - engineered_fusion_gene - - - Act57B::Act88F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267110 CR45550 - http://flybase.org/reports/FBgn0267110 non_protein_coding_gene - - - CR45550 - CR45550 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259717 CG42371 - http://flybase.org/reports/FBgn0259717 protein_coding_gene - - - CG42371 - CG42371 11-Aug-17 DroID_v2017_08 - - - - Mmus\Cebpzos Hsap\CEBPZOS FBgn0083251 E(smoDN)M Enhancer of smoDN group M http://flybase.org/reports/FBgn0083251 gene - smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "Group M, E(smoDN)M" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethalcell lethal,somatic clone,lethal,recessive" FBgn0033092 CG9422 - http://flybase.org/reports/FBgn0033092 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR013795 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR013795 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR013795 "BcDNA:RE35072, CG9422" "IPR002775:DNA/RNA-binding protein Alba-like, IPR013795:DNA/RNA-binding protein Alba" CG9422 11-Aug-17 DroID_v2017_08 Drer\rpp25l - Cele\ZK632.14 "Xtro\rpp25l, Xtro\rpp25" "Mmus\Rpp25l, Mmus\Rpp25" "Hsap\RPP25, Hsap\RPP25L" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell" FBgn0016781 anon-8Da anon-8Da http://flybase.org/reports/FBgn0016781 - gene - - - anon-8Da - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002767 mit(1)18 mitotic 18 http://flybase.org/reports/FBgn0002767 - gene - - - mit(1)18 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003216 rde reduced eye http://flybase.org/reports/FBgn0003216 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available rde - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective "eye,maxillary palpus" FBgn0005275 Les Lesbian http://flybase.org/reports/FBgn0005275 - gene - - - Les - - 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,female" FBgn0003337 Scoop Scoop http://flybase.org/reports/FBgn0003337 - gene - - - "Sc, Scp, Scoop" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile,body color defective" "wing,abdomen" FBgn0021783 l(3)95BCb lethal (3) 95BCb http://flybase.org/reports/FBgn0021783 - gene - - - l(3)95BCb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038660 CG14291 - http://flybase.org/reports/FBgn0038660 protein_coding_gene sulfuric ester hydrolase activity ; GO:0008484 | inferred from electronic annotation with InterPro:IPR000917 "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850" - CG14291 "IPR000917:Sulfatase, N-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site, IPR032506:Domain of unknown function DUF4976" CG14291 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-174i8.1, Drer\arsia, Drer\galns, Drer\LOC559800, Drer\ids, Drer\sgsh, Drer\LOC101884179, Drer\arsh, Drer\arsa, Drer\arsg, Drer\LOC563783" - - "Xtro\sgsh, Xtro\arsk, Xtro\sts, Xtro\arsb, Xtro\arsi, Xtro\ids, Xtro\arsh, Xtro\arsa.1, Xtro\arsj, Xtro\arsd" "Mmus\Ids, Mmus\Arsj, Mmus\Arsi, Mmus\Galns, Mmus\Arsg, Mmus\Arsa, Mmus\Sgsh, Mmus\Arsb" "Hsap\ARSE, Hsap\ARSA, Hsap\ARSF, Hsap\ARSH, Hsap\ARSD, Hsap\STS, Hsap\IDS, Hsap\SGSH, Hsap\ARSJ, Hsap\ARSB, Hsap\ARSG, Hsap\GALNS, Hsap\ARSI" viable FBgn0004557 Su(var)208 Suppressor of variegation 208 http://flybase.org/reports/FBgn0004557 - gene - - - "Su(var)208, 208" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0261266 zuc zucchini http://flybase.org/reports/FBgn0261266 protein_coding_gene "endoribonuclease activity, producing 5'-phosphomonoesters ; GO:0016891 | inferred from direct assay cardiolipin hydrolase activity ; GO:0035755 | inferred from direct assay" "RNA phosphodiester bond hydrolysis, endonucleolytic ; GO:0090502 | inferred from direct assay gene silencing by RNA ; GO:0031047 | inferred from mutant phenotype piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay P granule ; GO:0043186 | NOT inferred from direct assay "ZUC, zuc, CG12314, Zuc, MitoPLD" IPR025202:Phospholipase D-like domain CG12314 11-Aug-17 DroID_v2017_08 Drer\pld6 - - Xtro\pld6 Mmus\Pld6 Hsap\PLD6 FBgn0046875 Obp83g Odorant-binding protein 83g http://flybase.org/reports/FBgn0046875 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "Obp83f, 83g, CG15583, CG31558, BcDNA:RE27306, Obp83g, DmelObp83g, obp83g" IPR006170:Pheromone/general odorant binding protein CG31558 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039007 CCAP Crustacean cardioactive peptide http://flybase.org/reports/FBgn0039007 protein_coding_gene neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with CCAP-R neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity neuropeptide hormone activity ; GO:0005184 | non-traceable author statement positive regulation of heart rate ; GO:0010460 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay "CCAP, CG4910, DmCCAP, ccap, Ccap" IPR024276:Crustacean cardioactive peptide CG4910 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,eclosion rhythm defective" FBgn0261647 Axud1 AXIN1 up-regulated 1 http://flybase.org/reports/FBgn0261647 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from sequence or structural similarity with MGI:MGI:2387989 negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with MGI:MGI:2387989 nucleus ; GO:0005634 | inferred from direct assay "Axud1, BcDNA:GH09817, CG4272, DAxud1, C676" "IPR023260:Cysteine/serine-rich nuclear protein family, IPR031972:Cysteine/serine-rich nuclear protein, N-terminal domain" CG4272 11-Aug-17 DroID_v2017_08 "Drer\csrnp1a, Drer\csrnp1b, Drer\csrnp2" - Cele\C41D11.3 "Xtro\csrnp1, Xtro\csrnp2" "Mmus\Csrnp1, Mmus\Csrnp3, Mmus\Csrnp2" "Hsap\CSRNP3, Hsap\CSRNP1, Hsap\CSRNP2" FBgn0052226 Pex23 Peroxin 23 http://flybase.org/reports/FBgn0052226 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR001079 - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006614 "CG18565, CG6468, CG32226, Pex23, DmelPex23" "IPR001079:Galectin, carbohydrate recognition domain, IPR006614:Peroxin/Ferlin domain, IPR006624:Beta-propeller repeat TECPR, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR010482:Peroxin domain" CG32226 11-Aug-17 DroID_v2017_08 "Drer\lgals9l6, Drer\lgals3b, Drer\lgals8a, Drer\lgalslb, Drer\lgals9l4, Drer\lgals9l5, Drer\tecpr2, Drer\si:ch211-251f6.6, Drer\lgals9l3, Drer\tecpr1b, Drer\si:ch211-10a23.2, Drer\zgc:173443, Drer\lgals8b, Drer\lgals3a, Drer\zgc:136254, Drer\grifin, Drer\tecpr1a, Drer\lgals1l1, Drer\lgals9l1, Drer\lgalsla" - "Cele\lec-10, Cele\lec-5, Cele\lec-8, Cele\T01H3.2" "Xtro\LOC100216286, Xtro\lgals4, Xtro\LOC100496749, Xtro\lgals9, Xtro\tecpr2, Xtro\lgals1, Xtro\lgals3, Xtro\tecpr1, Xtro\lgals2, Xtro\lgalsl, Xtro\lgals9b, Xtro\lgals8" "Mmus\Lgals8, Mmus\Lgals7, Mmus\Lgals1, Mmus\Lgals12, Mmus\Tecpr1, Mmus\Lgals9, Mmus\Lgals2, Mmus\Grifin, Mmus\Lgals4, Mmus\Lgals3, Mmus\Tecpr2, Mmus\Lgalsl" "Hsap\OSTC, Hsap\LGALSL, Hsap\LGALS13, Hsap\LGALS4, Hsap\LGALS12, Hsap\TECPR2, Hsap\LGALS7, Hsap\LGALS14, Hsap\LGALS7B, Hsap\LGALS8, Hsap\CLC, Hsap\LGALS3, Hsap\LGALS1, Hsap\LGALS2, Hsap\TECPR1, Hsap\LGALS9B, Hsap\LGALS9C, Hsap\LGALS9" viable FBgn0030485 CG1998 - http://flybase.org/reports/FBgn0030485 protein_coding_gene iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006694 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000221168 lipid biosynthetic process ; GO:0008610 | inferred from electronic annotation with InterPro:IPR006694 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006694 lipid metabolic process ; GO:0006629 | inferred from biological aspect of ancestor with PANTHER:PTN000221168 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000221169 CG1998 IPR006694:Fatty acid hydroxylase CG1998 11-Aug-17 DroID_v2017_08 "Drer\msmo1, Drer\ch25h, Drer\ch25hl2, Drer\ch25hl1.2, Drer\faxdc2, Drer\ch25hl1.1" "Scer\ERG3, Scer\ERG25" "Cele\F49E12.10, Cele\drd-1" "Xtro\msmo1, Xtro\faxdc2" "Mmus\Sc5d, Mmus\Ch25h, Mmus\Msmo1" "Hsap\FAXDC2, Hsap\CH25H, Hsap\MSMO1" "viable,visible" trichogen cell FBgn0266710 hog hog http://flybase.org/reports/FBgn0266710 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "hog, CG32595" "IPR000253:Forkhead-associated (FHA) domain, IPR008984:SMAD/FHA domain" CG32595 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266026 CR44791 - http://flybase.org/reports/FBgn0266026 non_protein_coding_gene - - - CR44791 - CR44791 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021851 l(2)k14602 lethal (2) k14602 http://flybase.org/reports/FBgn0021851 - gene - - - l(2)k14602 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050095 CG30095 - http://flybase.org/reports/FBgn0050095 protein_coding_gene - - - "CG8425, CG30095" - CG30095 11-Aug-17 DroID_v2017_08 "Drer\nlgn3b, Drer\nlgn2b, Drer\ces3, Drer\nlgn2a, Drer\nlgn1, Drer\nlgn4b, Drer\cell, Drer\nlgn3a, Drer\cel.1, Drer\ces2, Drer\nlgn4a, Drer\si:ch211-93f2.1" - - "Xtro\cel, Xtro\nlgn3, Xtro\LOC100494782, Xtro\nlgn4x, Xtro\ces3, Xtro\ces2, Xtro\nlgn2" "Mmus\Ces3a, Mmus\Ces2f, Mmus\Ces2e, Mmus\Ces2b, Mmus\Ces4a, Mmus\Ces1d, Mmus\Ces2h, Mmus\Nlgn3, Mmus\Ces1c, Mmus\Ces1f, Mmus\Ces1e, Mmus\Ces1b, Mmus\Ces5a, Mmus\Nlgn1, Mmus\Ces3b, Mmus\Ces1h, Mmus\Ces2c, Mmus\Ces2a, Mmus\Cel, Mmus\Ces2g, Mmus\Ces1g, Mmus\Nlgn2" "Hsap\CES1, Hsap\CES2, Hsap\NLGN4Y, Hsap\NLGN3, Hsap\CES5A, Hsap\CEL, Hsap\NLGN4X, Hsap\NLGN1, Hsap\CES3, Hsap\NLGN2, Hsap\CES4A" "viable,fertile,visible" trichogen cell FBgn0040244 anon-57Bd anon-57Bd http://flybase.org/reports/FBgn0040244 gene - - - anon-57Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001925 l(2)25Cf lethal (2) 25Cf http://flybase.org/reports/FBgn0001925 - gene - - - "jf20, l(2)jf20, l(2)25Cf" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024500 Acp53Eb Accessory gland protein 53Eb http://flybase.org/reports/FBgn0024500 - gene - sperm displacement ; GO:0007321 | non-traceable author statement - Acp53Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058359 CG40359 - http://flybase.org/reports/FBgn0058359 protein_coding_gene - - - CG40359 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027341 Gfat1 Glutamine:fructose-6-phosphate aminotransferase 1 http://flybase.org/reports/FBgn0027341 "FBgn0058197, FBan0012449" protein_coding_gene carbohydrate derivative binding ; GO:0097367 | inferred from electronic annotation with InterPro:IPR001347 glutamine-fructose-6-phosphate transaminase (isomerizing) activity ; GO:0004360 | inferred from electronic annotation with InterPro:IPR005855 carbohydrate derivative biosynthetic process ; GO:1901137 | inferred from electronic annotation with InterPro:IPR005855 - "CG12449, Dmel/Gfat1, Gfat, gfat, GFAT, CG40197, Gfat1, gfat1" "IPR001347:Sugar isomerase (SIS), IPR005855:Glucosamine-fructose-6-phosphate aminotransferase, isomerising, IPR017932:Glutamine amidotransferase type 2 domain, IPR029055:Nucleophile aminohydrolases, N-terminal" CG12449 11-Aug-17 DroID_v2017_08 "Drer\gfpt2, Drer\gfpt1, Drer\LOC108179026" "Scer\YMR085W, Scer\GFA1, Scer\YMR084W" "Cele\gfat-1, Cele\gfat-2" "Xtro\gfpt1, Xtro\gfpt2" "Mmus\Gfpt1, Mmus\Gfpt2" "Hsap\GFPT1, Hsap\GFPT2" lethal FBgn0260959 MCPH1 Microcephalin http://flybase.org/reports/FBgn0260959 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "pole cell formation ; GO:0007279 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay "MCPH1, CG42572, CG8981, CG13184, Dmcph1, CG30038, mcph1, awol, dMCPH1, p91" "IPR001357:BRCT domain, IPR022047:Microcephalin-like" CG42572 11-Aug-17 DroID_v2017_08 "Drer\mcph1, Drer\bard1, Drer\trim109" - Cele\W04A8.1 "Xtro\bard1, Xtro\mcph1, Xtro\brca1" "Mmus\Mcph1, Mmus\Bard1" "Hsap\MCPH1, Hsap\BARD1" DRSC28302 K -0.268755354 0.143628475 -0.369184272 0.395835503 -1.749423958 0.281462988 FBgn0015765 p38a p38a MAP kinase http://flybase.org/reports/FBgn0015765 "FBgn0013952, FBgn0022991" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR003527, InterPro:IPR008352, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement SAP kinase activity ; GO:0016909 | traceable author statement MAP kinase activity ; GO:0004707 | inferred from sequence or structural similarity with HGNC:6876 inferred from genetic interaction with SGD:S000004103 MAP kinase activity ; GO:0004707 | inferred from direct assay" paracrine signaling ; GO:0038001 | inferred from genetic interaction with p38b defense response to fungus ; GO:0050832 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from genetic interaction with p38b MAPK cascade ; GO:0000165 | inferred from direct assay regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from genetic interaction with Ask1 MAPK cascade ; GO:0000165 | non-traceable author statement response to starvation ; GO:0042594 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype regulation of cellular response to oxidative stress ; GO:1900407 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement defense response to bacterium ; GO:0042742 | inferred from mutant phenotype negative regulation of antimicrobial humoral response ; GO:0008348 | inferred from mutant phenotype MAPK cascade ; GO:0000165 | inferred from sequence or structural similarity with HGNC:6876 cellular response to cadmium ion ; GO:0071276 | inferred from direct assay response to hydrogen peroxide ; GO:0042542 | inferred from mutant phenotype heart morphogenesis ; GO:0003007 | inferred from genetic interaction with p38b immune response ; GO:0006955 | inferred from direct assay response to oxidative stress ; GO:0006979 | inferred from mutant phenotype mucosal immune response ; GO:0002385 | inferred from mutant phenotype response to osmotic stress ; GO:0006970 | inferred from direct assay regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 cellular response to arsenic-containing substance ; GO:0071243 | inferred from direct assay cellular response to reactive oxygen species ; GO:0034614 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype reactive oxygen species metabolic process ; GO:0072593 | inferred from genetic interaction with p38b response to osmotic stress ; GO:0006970 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 "p38a, p38 alpha, D-p38a, P38, D-p38, p38, Dp38, p38A, CG5475, D-P38a, D-MPK2, DmMPK2, dMPK2, DMPK2, group 2, Erk2, p38Ka, dp38, Dmp38a, ERK2, mpk2, dp38a, D-p38 MAPK, Dp38a, Mpk2, MAPK2, p38alpha, MAPK-2" "IPR000719:Protein kinase domain, IPR003527:Mitogen-activated protein (MAP) kinase, conserved site, IPR008352:Mitogen-activated protein (MAP) kinase, p38, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG5475 11-Aug-17 DroID_v2017_08 "Drer\mapk4, Drer\mapk15, Drer\mapk12b, Drer\mapk14b, Drer\mapk11, Drer\mapk13, Drer\mapk12a, Drer\mapk7, Drer\mapk3, Drer\zgc:171775, Drer\mapk6, Drer\mapk14a, Drer\mapk1" "Scer\FUS3, Scer\HOG1, Scer\SNF1, Scer\CMK1, Scer\KDX1, Scer\KSS1, Scer\SMK1, Scer\SLT2" "Cele\pmk-1, Cele\pmk-3, Cele\F09C12.2, Cele\C05D10.2, Cele\mpk-2, Cele\mpk-1, Cele\pmk-2" "Xtro\LOC100145045, Xtro\mapk11, Xtro\mapk14, Xtro\mapk6, Xtro\mapk12, Xtro\mapk1, Xtro\mapk7, Xtro\mapk15, Xtro\mapk4" "Mmus\Mapk13, Mmus\Mapk4, Mmus\Mapk1, Mmus\Mapk15, Mmus\Mapk6, Mmus\Mapk7, Mmus\Mapk11, Mmus\Mapk12, Mmus\Mapk3, Mmus\Mapk14" "Hsap\MAPK7, Hsap\MAPK12, Hsap\MAPK6, Hsap\MAPK1, Hsap\MAPK3, Hsap\MAPK14, Hsap\MAPK11, Hsap\MAPK4, Hsap\MAPK15, Hsap\MAPK13" " embryonic stage | late , embryonic stage | early " embryonic/larval hindgut

"viable,reduced,fertile,stress response defective,recessive,starvation stress response defective,heat stress response defective,non-enhancer of variegation,non-suppressor of variegation,short lived,oxidative stress response defective,partially lethal - majority die,nutrition conditional,osmotic stress response defective,immune response defective" FBgn0267331 l(1)1Bb lethal (1) 1Bb http://flybase.org/reports/FBgn0267331 gene - - - "l(1)1Bb, l(1)EC4, EC4, l(1)C84, l(1)G4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0262892 CR43247 - http://flybase.org/reports/FBgn0262892 non_protein_coding_gene - - - "CG43247, CR43247, lincRNA.566" - CR43247 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065837 l(2)SH0335 lethal (2) SH0335 http://flybase.org/reports/FBgn0065837 gene - - - "l(2)SH0335, l(2)SH2 0335" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040362 CG11379 - http://flybase.org/reports/FBgn0040362 protein_coding_gene - - - "EG:BACR42I17.4, bs31h12.y1, CG11379" IPR032145:Protein of unknown function DUF4818 CG11379 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032406 CG14947 - http://flybase.org/reports/FBgn0032406 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14947 - CG14947 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026702 l(1)G0045 lethal (1) G0045 http://flybase.org/reports/FBgn0026702 "FBgn0027222, FBgn0027523, FBgn0052763" protein_coding_gene ribonuclease P activity ; GO:0004526 | inferred from biological aspect of ancestor with PANTHER:PTN000506667 ribonuclease MRP activity ; GO:0000171 | inferred from biological aspect of ancestor with PANTHER:PTN000506667 "tRNA 5'-leader removal ; GO:0001682 | inferred from electronic annotation with InterPro:IPR009723 tRNA processing ; GO:0008033 | inferred from biological aspect of ancestor with PANTHER:PTN000506667 RNA phosphodiester bond hydrolysis, endonucleolytic ; GO:0090502 | inferred from biological aspect of ancestor with PANTHER:PTN000506667" ribonuclease MRP complex ; GO:0000172 | inferred from biological aspect of ancestor with PANTHER:PTN000506667 nucleolar ribonuclease P complex ; GO:0005655 | inferred from biological aspect of ancestor with PANTHER:PTN000506667 "BcDNA:LD21623, l(1)G0312, CG4129, CG32763, l(1)G0045" "IPR009723:Ribonuclease P/MRP, subunit POP1, IPR012590:POPLD" CG32763 11-Aug-17 DroID_v2017_08 Drer\pop1 Scer\POP1 Cele\C05D11.9 Xtro\pop1 Mmus\Pop1 Hsap\POP1 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,male sterile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC17739 E -0.527536317 -0.900057836 0.119432033 1.61636595 -0.341868931 -0.496413408 FBgn0263235 Phae2 Phaedra 2 http://flybase.org/reports/FBgn0263235 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "CG16997, Phae2, SP147" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG16997 11-Aug-17 DroID_v2017_08 Drer\zmp:0000001088 - Cele\svh-1 - "Mmus\Prss57, Mmus\Prss44, Mmus\Prss53, Mmus\Klk1b3, Mmus\Prss36, Mmus\Prss29, Mmus\Klk1b27" "Hsap\PRSS36, Hsap\PRSS57, Hsap\PRSS53, Hsap\PRSS33" FBgn0025752 l(3)93Dk lethal (3) 93Dk http://flybase.org/reports/FBgn0025752 - gene - - - l(3)93Dk - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051914 tRNA:Asp-GTC-1-1 transfer RNA:Aspartic acid-GTC 1-1 http://flybase.org/reports/FBgn0051914 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "AE002690.trna23-AspGTC, tRNA:asp2:25D, tRNA:D2:25D, tRNA:D:GTC:AE002690-g, CR31914, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna33-AspGTC, tRNA:Asp-GTC-1-1, tRNA:CR31914, tRNA-Asp-GTC-1-1, GAC" - CR31914 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001948 l(2)27Cc lethal (2) 27Cc http://flybase.org/reports/FBgn0001948 - gene - - - "C, l(2)27Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262688 CR43158 - http://flybase.org/reports/FBgn0262688 pseudogene_attribute - - - CR43158 - CR43158 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263026 CG43321 - http://flybase.org/reports/FBgn0263026 protein_coding_gene molecular_function ; GO:0003674 | no biological data available calcium ion transmembrane import into mitochondrion ; GO:0036444 | inferred from electronic annotation with InterPro:IPR018782 mitochondrial calcium ion homeostasis ; GO:0051560 | inferred from electronic annotation with InterPro:IPR018782 biological_process ; GO:0008150 | no biological data available uniplex complex ; GO:1990246 | inferred from electronic annotation with InterPro:IPR018782 cellular_component ; GO:0005575 | no biological data available "CG43321, CG13776" "IPR018782:Essential MCU regulator, mitochondrial" CG43321 11-Aug-17 DroID_v2017_08 Drer\smdt1b - Cele\emre-1 Xtro\smdt1 Mmus\Smdt1 Hsap\SMDT1 FBgn0020377 Sr-CII "Scavenger receptor class C, type II" http://flybase.org/reports/FBgn0020377 FBgn0033700 protein_coding_gene polysaccharide binding ; GO:0030247 | inferred from electronic annotation with InterPro:IPR001212 scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001212 immune response ; GO:0006955 | inferred from electronic annotation with InterPro:IPR001212 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000998 "CG8856, CT25430, dSR-CII, Sr-CII, SR-CII" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR000436:Sushi/SCR/CCP domain, IPR000998:MAM domain, IPR001212:Somatomedin B domain" CG8856 11-Aug-17 DroID_v2017_08 "Drer\wu:fb63a08, Drer\mep1a.1, Drer\si:ch73-40a17.3, Drer\malrd1, Drer\mamdc1, Drer\mep1a.2, Drer\mep1b" - - Xtro\mdga2 "Mmus\Mdga1, Mmus\Mamdc2, Mmus\Cd55b, Mmus\Cd55, Mmus\Mdga2, Mmus\Malrd1" "Hsap\MDGA1, Hsap\MDGA2, Hsap\MALRD1, Hsap\MAMDC2" FBgn0266562 EP2265 - http://flybase.org/reports/FBgn0266562 gene - - - EP2265 - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/larval salivary gland FBgn0036162 CG6140 - http://flybase.org/reports/FBgn0036162 protein_coding_gene fumarate hydratase activity ; GO:0004333 | inferred from sequence or structural similarity with UniProtKB:P07954 fumarate metabolic process ; GO:0006106 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P07954 tricarboxylic acid cycle enzyme complex ; GO:0045239 | inferred from electronic annotation with InterPro:IPR005677 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P07954 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000154501 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P07954 CG6140 "IPR000362:Fumarate lyase family, IPR005677:Fumarate hydratase, class II, IPR008948:L-Aspartase-like, IPR024083:Fumarase/histidase, N-terminal, IPR018951:Fumarase C, C-terminal, IPR020557:Fumarate lyase, conserved site, IPR022761:Fumarate lyase, N-terminal" CG6140 11-Aug-17 DroID_v2017_08 "Drer\fh, Drer\LOC100535417" Scer\FUM1 Cele\fum-1 - Mmus\Fh1 Hsap\FH FBgn0028390 anon-50ABd anon-50ABd http://flybase.org/reports/FBgn0028390 gene - - - "D, anon-50ABd" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065511 l(2)SH1170 lethal (2) SH1170 http://flybase.org/reports/FBgn0065511 gene - - - "l(2)SH1170, l(2)SH2 1170" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0017626 Eig45Ab Eig45Ab http://flybase.org/reports/FBgn0017626 - gene - - - "Eig45-2, Eig45Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065866 l(2)SH0265 lethal (2) SH0265 http://flybase.org/reports/FBgn0065866 gene - - - "l(2)SH0265, l(2)SH2 0265" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026144 CBP sarcoplasmic calcium-binding protein http://flybase.org/reports/FBgn0026144 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "sarcoplasmic calcium-binding protein, CG1435, BcDNA.GH12350, BcDNA:GH12350, CBP, cbp, dCBP" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG1435 11-Aug-17 DroID_v2017_08 - - Cele\cex-2 - - Hsap\CALML3 "viable,lethal,recessive" intersegmental nerve FBgn0050385 CG30385 - http://flybase.org/reports/FBgn0050385 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT12446, CG11074, CG30385" "IPR032707:MYCBP-associated protein, IPR013783:Immunoglobulin-like fold" CG30385 11-Aug-17 DroID_v2017_08 Drer\mycbpap - - - Mmus\Mycbpap - "partially lethal - majority die,some die during pupal stage" FBgn0046706 Haspin Haspin http://flybase.org/reports/FBgn0046706 protein_coding_gene histone kinase activity (H3-T3 specific) ; GO:0072354 | inferred from sequence or structural similarity with HGNC:19682 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 ATP binding ; GO:0005524 | inferred from sequence or structural similarity with UniProtKB:Q8TF76 intracellular signal transduction ; GO:0035556 | inferred from sequence or structural similarity with UniProtKB:Q8TF76 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:Q8TF76 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q8TF76 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 "CG40080, BcDNA:LD07633, Haspin, haspin" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR024604:Serine/threonine-protein kinase haspin, C-terminal" CG40080 11-Aug-17 DroID_v2017_08 "Drer\eif2s1b, Drer\si:dkeyp-26a9.2, Drer\eif2s1a" "Scer\ALK2, Scer\ALK1" "Cele\hasp-1, Cele\C04G2.10, Cele\Y37E3.10, Cele\ZK177.2, Cele\H12I13.1, Cele\Y73B6A.1, Cele\C55C3.8, Cele\C06E4.5, Cele\F59E12.15, Cele\C26E6.1, Cele\Y48B6A.10, Cele\VY10G11R.1, Cele\hasp-2, Cele\C50H2.7" Xtro\eif2s1 "Mmus\Gsg2, Mmus\Eif2s1" "Hsap\EIF2S1, Hsap\GSG2" FBgn0002264 l(3)69Ac lethal (3) 69Ac http://flybase.org/reports/FBgn0002264 - gene - - - "rsg26, l(3)rsg26, l(3)69Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266904 CR45364 - http://flybase.org/reports/FBgn0266904 non_protein_coding_gene - - - "CR45364, lincRNA.73" - CR45364 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266381 CR45023 - http://flybase.org/reports/FBgn0266381 non_protein_coding_gene - - - CR45023 - CR45023 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023022 l(3)A215.1M3 lethal (3) A215.1M3 http://flybase.org/reports/FBgn0023022 - gene - - - l(3)A215.1M3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083313 E(smoDN)1338 Enhancer of smoDN 1338 http://flybase.org/reports/FBgn0083313 gene - - - E(smoDN)1338 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001840 l(1)ts1126 lethal (1) ts1126 http://flybase.org/reports/FBgn0001840 - gene - - - l(1)ts1126 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,visible,male sterile,body color defective" "abdominal tergite & macrochaeta | conditional ts,wing,heat sensitive,tergite" FBgn0002171 l(2)Sp14 lethal (2) Sp14 http://flybase.org/reports/FBgn0002171 - gene - - - l(2)Sp14 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259401 EP-1013 - http://flybase.org/reports/FBgn0259401 gene - - - EP-1013 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0015794 Rab18 Rab18 http://flybase.org/reports/FBgn0015794 FBgn0029784 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with rod inferred from physical interaction with Zw10 inferred from physical interaction with spartin inferred from physical interaction with TBC1D5 inferred from physical interaction with Lrrk GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 cell adhesion ; GO:0007155 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from biological aspect of ancestor with PANTHER:PTN000756441 early endosome ; GO:0005769 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 endoplasmic reticulum ; GO:0005783 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "AAF46057, DmRab18, DRabRP4, DRABR4, Rab-r4, CG3129, Rab18, Rab18/RP4, Rab-RP4, rab18, 24639915, O18337" "IPR025662:Sigma-54 interaction domain, ATP-binding site 1, IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3129 11-Aug-17 DroID_v2017_08 "Drer\rab18a, Drer\rab18b" Scer\YPT1 Cele\rab-18 Xtro\rab18 Mmus\Rab18 Hsap\RAB18 viable FBgn0035957 CG5144 - http://flybase.org/reports/FBgn0035957 protein_coding_gene "kinase activity ; GO:0016301 | inferred from electronic annotation with InterPro:IPR022413, InterPro:IPR022414, InterPro:IPR022415" regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG5144 "IPR000749:ATP:guanido phosphotransferase, IPR014746:Glutamine synthetase/guanido kinase, catalytic domain, IPR022414:ATP:guanido phosphotransferase, catalytic domain, IPR022415:ATP:guanido phosphotransferase active site, IPR022413:ATP:guanido phosphotransferase, N-terminal" CG5144 11-Aug-17 DroID_v2017_08 "Drer\ckmt2a, Drer\ckbb, Drer\ckmt1, Drer\pgm1, Drer\ckma, Drer\ckmt2b, Drer\ckmb, Drer\ckba, Drer\pgm5" - "Cele\R05F9.6, Cele\ZC434.8, Cele\F46H5.3, Cele\F32B5.1, Cele\W10C8.5, Cele\argk-1, Cele\F11G11.13" "Xtro\ckb, Xtro\pgm1, Xtro\pgm5, Xtro\ckm, Xtro\ckmt1b" "Mmus\Pgm5, Mmus\Ckmt2, Mmus\Pgm2, Mmus\Ckmt1, Mmus\Ckm, Mmus\Ckb" "Hsap\CKMT2, Hsap\PGM5, Hsap\CKMT1A, Hsap\CKMT1B, Hsap\CKB, Hsap\CKM, Hsap\PGM1" viable DRSC23349 EK -0.537180271 0.344312602 -1.928589298 0.084007894 -0.593226677 -1.584902688 FBgn0032637 CG5050 - http://flybase.org/reports/FBgn0032637 protein_coding_gene - - - CG5050 - CG5050 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001577 l(1)air4 lethal aberrant immune response 4 http://flybase.org/reports/FBgn0001577 - gene - - - "air4, l(1)air4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,embryonic/larval hindgut,embryonic/larval lymph gland,melanotic mass" FBgn0034215 Mtap Methylthioadenosine phosphorylase http://flybase.org/reports/FBgn0034215 protein_coding_gene S-methyl-5-thioadenosine phosphorylase activity ; GO:0017061 | inferred from electronic annotation with InterPro:IPR010044 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 cellular_component ; GO:0005575 | no biological data available "CG4802, MTAP, Mtap" "IPR010044:Methylthioadenosine phosphorylase (MTAP), IPR000845:Nucleoside phosphorylase domain, IPR018099:Purine phosphorylase, family 2, conserved site" CG4802 11-Aug-17 DroID_v2017_08 Drer\mtap "Scer\MEU1, Scer\PNP1" Cele\B0228.7 Xtro\mtap Mmus\Mtap "Hsap\PNP, Hsap\MTAP" "lethal,partially lethal - majority die" FBgn0053774 CG33774 - http://flybase.org/reports/FBgn0053774 protein_coding_gene dolichyl-diphosphooligosaccharide-protein glycotransferase activity ; GO:0004579 | inferred from sequence or structural similarity with UniProtKB:Q99380 protein N-linked glycosylation ; GO:0006487 | inferred from sequence or structural similarity with UniProtKB:Q99380 oligosaccharyltransferase complex ; GO:0008250 | inferred from sequence or structural similarity with UniProtKB:Q99380 "BcDNA:GM20929, CG33774, Dm_2R:21419" IPR018943:Oligosaccaryltransferase CG33774 11-Aug-17 DroID_v2017_08 Drer\ost4 - Cele\T07A5.5 - Mmus\Ost4 Hsap\OST4 FBgn0266281 CR44966 - http://flybase.org/reports/FBgn0266281 non_protein_coding_gene - - - CR44966 - CR44966 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027134 l(3)93Ea lethal (3) 93Ea http://flybase.org/reports/FBgn0027134 - gene - - - l(3)93Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002662 mat(2)cell-K maternal effect cellularisation defect K http://flybase.org/reports/FBgn0002662 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "cell-RH36, mat(2)cellRH36, mat(2)cell-K" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,partially,some die during embryonic stage" "stage 5 embryo,maternal effect" FBgn0003005 opht opthalmoptera http://flybase.org/reports/FBgn0003005 - gene - - - opht - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037565 CG9626 - http://flybase.org/reports/FBgn0037565 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG9626, Q9VHT6_DROME" - CG9626 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029646 CG14423 - http://flybase.org/reports/FBgn0029646 protein_coding_gene - - - CG14423 - CG14423 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259760 ms(3)Z3-5231 - http://flybase.org/reports/FBgn0259760 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "165-104, ms(3)Z3-5231, ms(3)165-104" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male sterile" "Y chromosome loop,spermatozoon" FBgn0035921 CG13305 - http://flybase.org/reports/FBgn0035921 protein_coding_gene - - - "CT32600, BcDNA:RE33542, CG13305" - CG13305 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266941 CR45392 - http://flybase.org/reports/FBgn0266941 non_protein_coding_gene - - - "lincRNA.596, CR45392" - CR45392 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003257 r-l rudimentary-like http://flybase.org/reports/FBgn0003257 - protein_coding_gene orotidine-5'-phosphate decarboxylase activity ; GO:0004590 | inferred from mutant phenotype orotate phosphoribosyltransferase activity ; GO:0004588 | inferred from mutant phenotype "'de novo' UMP biosynthetic process ; GO:0044205 | inferred from electronic annotation with InterPro:IPR014732 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from electronic annotation with InterPro:IPR001754, InterPro:IPR018089 sleep ; GO:0030431 | inferred from expression pattern 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred by curator from GO:0004588,GO:0004590" microtubule associated complex ; GO:0005875 | inferred from direct assay "r-l, UMPS, OPRT, OMPDC, ral, CG3593" "IPR018089:Orotidine 5'-phosphate decarboxylase, active site, IPR000836:Phosphoribosyltransferase domain, IPR001754:Orotidine 5'-phosphate decarboxylase domain, IPR004467:Orotate phosphoribosyl transferase domain, IPR011060:Ribulose-phosphate binding barrel, IPR013785:Aldolase-type TIM barrel, IPR014732:Orotidine 5'-phosphate decarboxylase, IPR029057:Phosphoribosyltransferase-like, IPR023031:Orotate phosphoribosyltransferase" CG3593 11-Aug-17 DroID_v2017_08 Drer\umps "Scer\URA10, Scer\URA3, Scer\URA5" "Cele\R12E2.11, Cele\umps-1" Xtro\umps Mmus\Umps Hsap\UMPS embryonic stage "viable,fertile" DRSC22784 I 2.177167721 0.736069189 0.739114062 0.34410855 -0.154263108 -0.910030252 FBgn0262985 CG43293 - http://flybase.org/reports/FBgn0262985 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43293 - CG43293 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000618 e(y)2 enhancer of yellow 2 http://flybase.org/reports/FBgn0000618 FBgn0030315 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9U3V9 C2H2 zinc finger domain binding ; GO:0070742 | inferred from physical interaction with su(Hw) protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q27272 chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P08970 chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay TFIID-class transcription factor binding ; GO:0001094 | inferred from physical interaction with e(y)1 inferred from physical interaction with Tbp inferred from physical interaction with Taf10 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000282153 "negative regulation of chromatin silencing ; GO:0031936 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | inferred from direct assay histone deubiquitination ; GO:0016578 | inferred from direct assay" nuclear pore ; GO:0005643 | inferred from direct assay DUBm complex ; GO:0071819 | inferred from direct assay transcription export complex 2 ; GO:0070390 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear periphery ; GO:0034399 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay inferred from physical interaction with Gcn5 inferred from physical interaction with Taf10 inferred from physical interaction with Ada2b inferred from physical interaction with Nipped-A SAGA complex ; GO:0000124 | inferred from direct assay "e(y)2, d, CG15191, e(y)[2], ENY2, E(y)2, Sus1, LBC" "IPR018783:Transcription factor, enhancer of yellow 2" CG15191 11-Aug-17 DroID_v2017_08 Drer\eny2 Scer\SUS1 Cele\T01C3.2 Xtro\eny2 Mmus\Eny2 Hsap\ENY2 "visible,recessive,viable,partially lethal - majority die,some die during pupal stage" "wing,eye,macrochaeta,mesothoracic tergum" FBgn0062603 Mod(var)1444 Mod(var)1444 http://flybase.org/reports/FBgn0062603 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1444, Mod(var)1444" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0085711 CG41587 - http://flybase.org/reports/FBgn0085711 protein_coding_gene - - - CG41587 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044461 EP3303 EP3303 http://flybase.org/reports/FBgn0044461 gene - - - EP3303 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "anterior fascicle & synapse,intersegmental nerve" FBgn0267175 CR45615 - http://flybase.org/reports/FBgn0267175 non_protein_coding_gene - - - CR45615 - CR45615 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027279 l(1)G0196 lethal (1) G0196 http://flybase.org/reports/FBgn0027279 "FBgn0031192, FBgn0052502" protein_coding_gene "acid phosphatase activity ; GO:0003993 | inferred from electronic annotation with InterPro:IPR000560 inositol-1,3,4,5,6-pentakisphosphate kinase activity ; GO:0000827 | inferred from sequence or structural similarity with HGNC:29023 ATP binding ; GO:0005524 | inferred from sequence or structural similarity with UniProtKB:O43314 diphosphoinositol-pentakisphosphate kinase activity ; GO:0033857 | inferred from biological aspect of ancestor with PANTHER:PTN000297581 diphosphoinositol-pentakisphosphate kinase activity ; GO:0033857 | inferred from sequence or structural similarity with UniProtKB:Q6PFW1 inositol hexakisphosphate 5-kinase activity ; GO:0000832 | inferred from sequence or structural similarity with UniProtKB:Q6PFW1 inositol-1,3,4,5,6-pentakisphosphate kinase activity ; GO:0000827 | inferred from sequence or structural similarity with UniProtKB:Q6PFW1 inositol hexakisphosphate kinase activity ; GO:0000828 | inferred from biological aspect of ancestor with PANTHER:PTN000297581 inositol heptakisphosphate kinase activity ; GO:0000829 | inferred from biological aspect of ancestor with PANTHER:PTN000297581 diphosphoinositol-pentakisphosphate kinase activity ; GO:0033857 | inferred from sequence or structural similarity with HGNC:29023 inositol hexakisphosphate 5-kinase activity ; GO:0000832 | inferred from sequence or structural similarity with HGNC:29023" inositol metabolic process ; GO:0006020 | inferred from biological aspect of ancestor with PANTHER:PTN000297581 inositol metabolic process ; GO:0006020 | inferred from sequence or structural similarity with UniProtKB:Q6PFW1 inositol phosphate biosynthetic process ; GO:0032958 | inferred from biological aspect of ancestor with PANTHER:PTN000297581 inositol metabolic process ; GO:0006020 | inferred from sequence or structural similarity with HGNC:29023 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000297583 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:Q6PFW1 "CG14616, CG32502, l(1)G0196" "IPR000560:Histidine phosphatase superfamily, clade-2, IPR029033:Histidine phosphatase superfamily, IPR033379:Histidine acid phosphatase active site" CG14616 11-Aug-17 DroID_v2017_08 "Drer\ppip5k2, Drer\ppip5k1a, Drer\ppip5k1b" Scer\VIP1 Cele\F46F11.1 "Xtro\ppip5k2, Xtro\ppip5k1" "Mmus\Ppip5k1, Mmus\Ppip5k2" "Hsap\PPIP5K1, Hsap\PPIP5K2" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" DRSC20591 IE 1.305293718 -1.50873131 -0.118072167 -1.641573426 -0.06570399 0.247059908 FBgn0021900 l(2)k12502b lethal (2) k12502b http://flybase.org/reports/FBgn0021900 - gene - - - l(2)k12502b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032625 CG15136 - http://flybase.org/reports/FBgn0032625 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15136 "IPR009818:Ataxin-2, C-terminal" CG15136 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065682 l(2)SH0662 lethal (2) SH0662 http://flybase.org/reports/FBgn0065682 gene - - - "l(2)SH0662, l(2)SH2 0662" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032680 Ntf-2r Nuclear transport factor-2-related http://flybase.org/reports/FBgn0032680 protein_coding_gene - transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR002075 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR002075 "Dntf-2r, CG10174, Ntf-2r, Dntf-2, Dntf-2R" "IPR018222:Nuclear transport factor 2, eukaryote, IPR002075:Nuclear transport factor 2, IPR032710:NTF2-like domain" CG10174 11-Aug-17 DroID_v2017_08 "Drer\nutf2l, Drer\nutf2" Scer\NTF2 Cele\ran-4 Xtro\nutf2 "Mmus\Nutf2, Mmus\Nutf2-ps2" Hsap\NUTF2 adult stage | male testis

"viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval hemocyte | third instar larval stage FBgn0011704 RnrS Ribonucleoside diphosphate reductase small subunit http://flybase.org/reports/FBgn0011704 FBgn0062214 protein_coding_gene "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ; GO:0004748 | inferred from biological aspect of ancestor with PANTHER:PTN001158161" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000358, InterPro:IPR012348 activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype deoxyribonucleotide biosynthetic process ; GO:0009263 | inferred from biological aspect of ancestor with PANTHER:PTN001158161 neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "rnr2, RNR2, dRNR2, RNrS, Rnr2, DmRNR2, CG8975, anon-WO0118547.148, RnrS, Rnrs, RNRS, rnrS" "IPR000358:Ribonucleotide reductase small subunit family, IPR009078:Ferritin-like superfamily, IPR030475:Ribonucleotide reductase small subunit, acitve site, IPR033909:Ribonucleotide reductase small subunit" CG8975 11-Aug-17 DroID_v2017_08 "Drer\rrm2b, Drer\rrm2, Drer\rrm2" "Scer\RNR4, Scer\RNR2" "Cele\F54H12.2, Cele\rnr-2, Cele\K09F6.5, Cele\F58F9.1, Cele\F19G12.2" "Xtro\rrm2.2, Xtro\rrm2.1, Xtro\rrm2b" "Mmus\Rrm2, Mmus\Rrm2b" "Hsap\RRM2, Hsap\RRM2B" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC07533 IEK -0.461226461 -3.13410515 -0.594178831 -2.859487957 2.544209042 2.992067892 FBgn0011896 tRNA:Lys-CTT-1-10 transfer RNA:Lysine-CTT 1-10 http://flybase.org/reports/FBgn0011896 "FBgn0011886, FBgn0050242, FBgn0050507, FBgn0060179" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "tRNA[Lys][[2]], AE002787.trna16-LysCTT, tRNA:K2, tRNA:K:CTT:AE002787-a, tRNA:lys2:50C, CR30242, CR30507, tRNAlys, chr2R.trna75-LysCTT, tRNA-Lys-CTT-1-10, tRNA:Lys-CTT-1-10, tRNA:K2:50C, AAG" - CR30507 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005027 dw-sc dwarf with scute http://flybase.org/reports/FBgn0005027 - gene - - - dw-sc - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced" "adult abdomen,adult thorax" FBgn0260745 mfas midline fasciclin http://flybase.org/reports/FBgn0260745 protein_coding_gene cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity withFB:FBgn0262742 negative regulation of hemocyte proliferation ; GO:0035207 | inferred from genetic interaction with hop multicellular organism reproduction ; GO:0032504 | inferred from expression pattern axonogenesis ; GO:0007409 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "mfas, CG3359, clone 97, gh06752, BEST:GH06752, anon-EST:Liang-97, anon-WO0140519.174, 87A7-9/7, anon-87Af, Mfas" "IPR000782:FAS1 domain, IPR011489:EMI domain" CG3359 11-Aug-17 DroID_v2017_08 "Drer\postnb, Drer\postna, Drer\tgfbi, Drer\stab2" Scer\YLR001C Cele\F26E4.7 "Xtro\tgfbi, Xtro\postn" "Mmus\Postn, Mmus\Tgfbi, Mmus\Stab2" "Hsap\TGFBI, Hsap\POSTN, Hsap\STAB2" FBgn0085715 CG41595 - http://flybase.org/reports/FBgn0085715 protein_coding_gene - - - CG41595 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032004 CG8292 - http://flybase.org/reports/FBgn0032004 protein_coding_gene - - - CG8292 - CG8292 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0061165 l(1)3As lethal (1) 3As http://flybase.org/reports/FBgn0061165 gene - - - l(1)3As - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051575 tRNA:Ala-AGC-2-9 transfer RNA:Alanine-AGC 2-9 http://flybase.org/reports/FBgn0051575 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "tRNA-ala, AE002708.trna43-AlaAGC, tRNA:A:AGC:AE002708-g, CR31575, tRNA[[Ala]], chr3R.trna49-AlaAGC, tRNA-Ala-AGC-2-9, tRNA:Ala-AGC-2-9, tRNA:CR31575, GCU" - CR31575 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011854 tRNA:Glu-CTC-3-8 transfer RNA:Glutamic acid-CTC 3-8 http://flybase.org/reports/FBgn0011854 "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052323, FBgn0060246" tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "AE002584.trna10-GluCTC, tRNA:E4, tRNA:E:CTC:AE002584-h, tRNA:glu4:62Ad, CR32323, tRNA:Glu, chr3L.trna10-GluCTC, tRNA:Glu-CTC-3-8, tRNA:E4:62Ad, tRNA-Glu-CTC-3-8, GAG" - CR32323 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014402 vah ventral abdominal hole http://flybase.org/reports/FBgn0014402 - gene - - - vah - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "central nervous system,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt" FBgn0003418 sla slimma http://flybase.org/reports/FBgn0003418 - gene - - - sla - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male fertile,viable,male,female,reduced,female sterile" "adult abdomen,wing" FBgn0031304 CG4552 - http://flybase.org/reports/FBgn0031304 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype - CG4552 "IPR000195:Rab-GTPase-TBC domain, IPR001763:Rhodanese-like domain" CG4552 11-Aug-17 DroID_v2017_08 Drer\tbc1d23 - Cele\tbc-1 Xtro\tbc1d23 Mmus\Tbc1d23 Hsap\TBC1D23 "cell migration defective,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "border follicle cell,mesothoracic tergum" FBgn0011702 Res Resurrector http://flybase.org/reports/FBgn0011702 - gene - - - "Res1, Res" - - 11-Aug-17 DroID_v2017_08 - - - - - - mitotic cell cycle defective "embryonic abdomen,cleavage nucleus" FBgn0266723 Trs31 TRAPP subunit 31 http://flybase.org/reports/FBgn0266723 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000002880 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000002880 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000002880 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity "CG10153, Trs31p, Trs31" "IPR007194:Transport protein particle (TRAPP) component, IPR016696:TRAPP I complex, subunit 5, IPR024096:NO signalling/Golgi transport ligand-binding domain" CG10153 11-Aug-17 DroID_v2017_08 Drer\trappc5 Scer\TRS31 Cele\trpp-5 Xtro\trappc5 Mmus\Trappc5 Hsap\TRAPPC5 FBgn0029153 Menl-2 Malic enzyme like-2 http://flybase.org/reports/FBgn0029153 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NAD+) activity ; GO:0004471 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:0004473 | inferred from biological aspect of ancestor with PANTHER:PTN000601052" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000601050 pyruvate metabolic process ; GO:0006090 | inferred from biological aspect of ancestor with PANTHER:PTN000601050" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001157886 "CG7969, CG30097, Menl-2" "IPR001891:Malic oxidoreductase, IPR012301:Malic enzyme, N-terminal domain, IPR012302:Malic enzyme, NAD-binding, IPR016040:NAD(P)-binding domain" CG7969 11-Aug-17 DroID_v2017_08 "Drer\me3, Drer\me1, Drer\LOC101882012, Drer\me2" Scer\MAE1 Cele\men-1 "Xtro\me2, Xtro\me3" "Mmus\Me1, Mmus\Me3, Mmus\Me2" "Hsap\ME2, Hsap\ME1, Hsap\ME3" FBgn0266102 CR44839 - http://flybase.org/reports/FBgn0266102 pseudogene_attribute - - - CR44839 - CR44839 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085423 CG34394 - http://flybase.org/reports/FBgn0085423 protein_coding_gene - - - "CG34394, CG15411, BcDNA:RE58243, CG3304" "IPR004182:GRAM domain, IPR031968:VASt domain" CG34394 11-Aug-17 DroID_v2017_08 "Drer\gramd1c, Drer\gramd2a, Drer\gramd1a, Drer\gramd1ba, Drer\LOC100335008, Drer\gramd1bb" "Scer\LAM5, Scer\YSP2, Scer\LAM6, Scer\LAM4" Cele\ZC328.3 "Xtro\gramd1b, Xtro\gramd3, Xtro\gramd1c" "Mmus\Gramd1a, Mmus\Gramd3, Mmus\Gramd1b, Mmus\Gramd1c, Mmus\Gramd2" "Hsap\GRAMD1B, Hsap\GRAMD3, Hsap\GRAMD1C, Hsap\GRAMD2, Hsap\GRAMD1A" "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053341 CG33341 - http://flybase.org/reports/FBgn0053341 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33341 IPR006631:Protein of unknown function DM4/12 CG33341 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085475 CG34446 - http://flybase.org/reports/FBgn0085475 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34446, CG13513, CG30219" IPR006629:LPS-induced tumour necrosis factor alpha factor CG34446 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001712 l(1)ESHS33 lethal (1) ESHS33 http://flybase.org/reports/FBgn0001712 - gene - - - l(1)ESHS33 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027521 CG3679 - http://flybase.org/reports/FBgn0027521 - protein_coding_gene - - - "BcDNA:LD21675, CG3679" - CG3679 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0259389 C107 - http://flybase.org/reports/FBgn0259389 gene - - - C107 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0033556 CG12343 - http://flybase.org/reports/FBgn0033556 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:19824 "neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay post-mRNA release spliceosomal complex ; GO:0071014 | inferred from biological aspect of ancestor with PANTHER:PTN000327519 Prp19 complex ; GO:0000974 | inferred from biological aspect of ancestor with PANTHER:PTN000327519 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG12343, Syf2" IPR013260:mRNA splicing factor SYF2 CG12343 11-Aug-17 DroID_v2017_08 Drer\syf2 Scer\SYF2 Cele\K04G7.11 Xtro\syf2 Mmus\Syf2 Hsap\SYF2 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" DRSC06135 E -0.220023632 0.515060148 1.792929796 0.956395364 -0.69217173 0.349297846 FBgn0028065 l(3)S091306 lethal (3) S091306 http://flybase.org/reports/FBgn0028065 gene - - - "0913/06, l(3)S091306" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002278 l(3)73Ac lethal (3) 73Ac http://flybase.org/reports/FBgn0002278 - gene - - - "l(3)std2, l(3)73Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0039360 CLS Cardiolipin synthase http://flybase.org/reports/FBgn0039360 protein_coding_gene cardiolipin synthase activity ; GO:0008808 | inferred from direct assay cardiolipin biosynthetic process ; GO:0032049 | inferred from biological aspect of ancestor with PANTHER:PTN000370438 ATP biosynthetic process ; GO:0006754 | inferred from direct assay mitochondrial membrane organization ; GO:0007006 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000462 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000370358 "CLS, CG4774" IPR000462:CDP-alcohol phosphatidyltransferase CG4774 11-Aug-17 DroID_v2017_08 "Drer\crls1, Drer\cecr5, Drer\zgc:77375" "Scer\YKR070W, Scer\CRD1" "Cele\H32C10.1, Cele\crls-1" Xtro\crls1 "Mmus\Crls1, Mmus\Cecr5" "Hsap\CECR5, Hsap\CRLS1" viable mitochondrion FBgn0051912 CR31912 - http://flybase.org/reports/FBgn0051912 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31912, CR31912" - CR31912 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004208 l(3)84Ef lethal (3) 84Ef http://flybase.org/reports/FBgn0004208 - gene - - - l(3)84Ef - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038868 CG5862 - http://flybase.org/reports/FBgn0038868 protein_coding_gene ubiquitin-like protein ligase binding ; GO:0044389 | inferred from sequence or structural similarity with HGNC:16110 positive regulation of NF-kappaB transcription factor activity ; GO:0051092 | inferred from sequence or structural similarity with HGNC:16110 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:16110 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000327827 CG5862 "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR019153:DDRGK domain containing protein" CG5862 11-Aug-17 DroID_v2017_08 Drer\ddrgk1 - Cele\ufbp-1 Xtro\ddrgk1 Mmus\Ddrgk1 Hsap\DDRGK1 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0052649 CG32649 - http://flybase.org/reports/FBgn0052649 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with SGD:S000003087 "mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with SGD:S000003087" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000003087 "CG4410, CG32649" "IPR004147:UbiB domain, IPR011009:Protein kinase-like domain, IPR034646:UbiB domain, ADCK3-like" CG32649 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-36g24.3, Drer\adck3, Drer\adck4" Scer\COQ8 Cele\coq-8 "Xtro\adck3, Xtro\adck4" "Mmus\Coq8a, Mmus\Coq8b" "Hsap\COQ8B, Hsap\COQ8A" viable FBgn0000595 Etd Eye tissue determiner http://flybase.org/reports/FBgn0000595 - gene - - - Etd - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,ventral" FBgn0034736 gas gasoline http://flybase.org/reports/FBgn0034736 protein_coding_gene - detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype - "CG6018, DmalphaE1-O, alphaE1-O, gas" "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG6018 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-93f2.1, Drer\ces3, Drer\nlgn3a, Drer\nlgn3b, Drer\nlgn4b, Drer\nlgn2b, Drer\LOC100334697, Drer\cell, Drer\cel.1, Drer\nlgn1, Drer\nlgn2a, Drer\nlgn4a, Drer\ces2" - "Cele\ace-3, Cele\T07H6.1, Cele\ace-4, Cele\F07C4.12, Cele\B0238.1, Cele\T28C12.4, Cele\F15A8.6, Cele\T28C12.5, Cele\Y71H2AM.13, Cele\F56C11.6" "Xtro\cel, Xtro\nlgn2, Xtro\nlgn4x, Xtro\ces3, Xtro\ces2, Xtro\LOC100494782, Xtro\nlgn3" "Mmus\Ces2c, Mmus\Ces1e, Mmus\Ces1c, Mmus\Nlgn2, Mmus\Ces1g, Mmus\Ces2g, Mmus\Ces2h, Mmus\Ces1d, Mmus\Nlgn3, Mmus\Nlgn1, Mmus\Ces2f, Mmus\Ces2a, Mmus\Ces3a, Mmus\Ces1f, Mmus\Ces5a, Mmus\Ces2b, Mmus\Ces3b, Mmus\Cel, Mmus\Ces2e, Mmus\Ces1b, Mmus\Ces4a, Mmus\Ces1h" "Hsap\NLGN4Y, Hsap\NLGN2, Hsap\NLGN1, Hsap\NLGN3, Hsap\CEL, Hsap\CES2, Hsap\CES3, Hsap\CES1, Hsap\NLGN4X, Hsap\CES5A, Hsap\CES4A" viable FBgn0028067 l(3)S090609 lethal (3) S090609 http://flybase.org/reports/FBgn0028067 gene - - - "0906/09, l(3)S090609" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262824 CG43195 - http://flybase.org/reports/FBgn0262824 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43195 - CG43195 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045498 Gr22d Gustatory receptor 22d http://flybase.org/reports/FBgn0045498 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity with Gr5a male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from sequence or structural similarity with Gr5a response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | inferred from sequence model axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr22dP, Gr2940.2, CR31930, Gr22d, CG31930, GR22d" IPR013604:7TM chemoreceptor CG31930 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - FBgn0023549 Mct1 Monocarboxylate transporter 1 http://flybase.org/reports/FBgn0023549 - protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "EG:103B4.3, CG3456, Mct1" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG3456 11-Aug-17 DroID_v2017_08 "Drer\slc16a6a, Drer\si:ch211-234h8.7, Drer\slc16a4, Drer\slc16a9b, Drer\slc16a12b, Drer\slc16a7, Drer\slc16a6b, Drer\si:dkey-246g23.4, Drer\zgc:114041, Drer\LOC103911912, Drer\slc16a5b, Drer\slc16a13, Drer\slc16a1a, Drer\mfsd6b, Drer\slc16a5a, Drer\slc16a9a, Drer\slc16a12a" "Scer\MCH4, Scer\MCH5, Scer\ESBP6, Scer\MCH2, Scer\ATG22" "Cele\mct-6, Cele\mct-4, Cele\mct-5, Cele\mct-3, Cele\mct-1, Cele\mct-2" "Xtro\slc16a9, Xtro\slc16a2, Xtro\slc16a7, Xtro\slc16a12, Xtro\slc16a5, Xtro\slc16a3" "Mmus\Slc16a11, Mmus\Slc16a9, Mmus\Slc16a6, Mmus\Slc16a4, Mmus\Slc16a14, Mmus\Slc16a12, Mmus\Slc16a13, Mmus\Slc16a5" "Hsap\SLC16A11, Hsap\SLC16A8, Hsap\SLC16A6, Hsap\SLC16A5, Hsap\SLC16A1, Hsap\SLC16A14, Hsap\SLC16A12, Hsap\SLC16A10, Hsap\SLC16A4, Hsap\SLC16A13, Hsap\SLC16A9" FBgn0002813 ms(1)V7 male sterile (1) V7 http://flybase.org/reports/FBgn0002813 - gene - - - ms(1)V7 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0003246 rgt reduced pigment http://flybase.org/reports/FBgn0003246 - gene - - - rgt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,viable,male,body color defective" pigment cell FBgn0025740 PlexB Plexin B http://flybase.org/reports/FBgn0025740 FBgn0024198 protein_coding_gene "semaphorin receptor activity ; GO:0017154 | inferred from electronic annotation with InterPro:IPR031146, InterPro:IPR031148 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O96681 inferred from physical interaction with UniProtKB:Q24323" semaphorin-plexin signaling pathway ; GO:0071526 | inferred from electronic annotation with InterPro:IPR031148 negative regulation of cell adhesion ; GO:0007162 | inferred from biological aspect of ancestor with PANTHER:PTN001861955 motor neuron axon guidance ; GO:0008045 | non-traceable author statement negative regulation of Rac protein signal transduction ; GO:0035021 | non-traceable author statement dendrite self-avoidance ; GO:0070593 | inferred from mutant phenotype positive regulation of Rho protein signal transduction ; GO:0035025 | non-traceable author statement motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with Rac1 regulation of GTPase activity ; GO:0043087 | inferred from biological aspect of ancestor with PANTHER:PTN001861955 axon guidance ; GO:0007411 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN001861955 sensory neuron axon guidance ; GO:0097374 | inferred from mutant phenotype inferred from genetic interaction with Sema2a positive regulation of axonogenesis ; GO:0050772 | inferred from biological aspect of ancestor with PANTHER:PTN001861955 olfactory bulb axon guidance ; GO:0071678 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay "PlexB, plex, CG17245, plexB, PLEXB, plex B, Plex B" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001627:Sema domain, IPR002165:Plexin repeat, IPR002909:IPT domain, IPR008936:Rho GTPase activation protein, IPR013548:Plexin, cytoplasmic RasGAP domain, IPR014756:Immunoglobulin E-set, IPR016201:PSI domain, IPR013783:Immunoglobulin-like fold, IPR031148:Plexin family" CG17245 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-183c2.4, Drer\plxnb1b, Drer\plxnb2b, Drer\plxnb3, Drer\plxna1b, Drer\met, Drer\plxnc1, Drer\plxna2, Drer\plxnd1, Drer\plxnb1a, Drer\plxnb2a, Drer\plxna1a, Drer\plxna3, Drer\mst1ra, Drer\si:ch211-127b11.1, Drer\plxna4" - "Cele\plx-2, Cele\plx-1" "Xtro\mst1r, Xtro\plxnc1, Xtro\plxna1, Xtro\dleu7, Xtro\plxnb3, Xtro\plxna4, Xtro\plxna2, Xtro\plxnb1, Xtro\plxna3, Xtro\met, Xtro\plxnd1" "Mmus\Plxna1, Mmus\Plxna3, Mmus\Plxnc1, Mmus\Plxnd1, Mmus\Mst1r, Mmus\Plxna4, Mmus\Met, Mmus\Plxnb1, Mmus\Plxnb2, Mmus\Plxna2, Mmus\Plxnb3" "Hsap\PLXNA2, Hsap\PLXNA4, Hsap\MST1R, Hsap\PLXNB1, Hsap\PLXND1, Hsap\PLXNA1, Hsap\PLXNB3, Hsap\MET, Hsap\PLXNB2, Hsap\PLXNA3, Hsap\PLXNC1" " embryonic stage , embryonic stage | stage >=9 , embryonic stage | early " " myoblast

, neuron

, embryonic central nervous system

,

ubiquitous " "viable,neuroanatomy defective,behavior defective,partially lethal - majority die" "intermediate longitudinal fascicle,MP1 tract,scolopidial neuron,adult olfactory receptor neuron,intersegmental nerve,segmental nerve branch SNa of A1-7,medial longitudinal fascicle,intersegmental nerve branch ISNb of A1-7,RP3 motor neuron" FBgn0021586 DdbP1 Damage-specific DNA-binding protein 1 http://flybase.org/reports/FBgn0021586 - gene damaged DNA binding ; GO:0003684 | inferred from direct assay endodeoxyribonuclease activity ; GO:0004520 | inferred from direct assay "nucleotide-excision repair, DNA incision, 3'-to lesion ; GO:0006295 | inferred from direct assay nucleotide-excision repair, DNA incision, 5'-to lesion ; GO:0006296 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "D-DDB P1, DdbP1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005557 l(3)89Ea lethal (3) 89Ea http://flybase.org/reports/FBgn0005557 "FBgn0002367, FBgn0002438" gene - - - "l(3)M182, llb, lbl, llB, l(3)lb, l(3)lB, l(3)89Ea" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036323 CG14118 - http://flybase.org/reports/FBgn0036323 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - CG14118 IPR001604:DNA/RNA non-specific endonuclease CG14118 11-Aug-17 DroID_v2017_08 "Drer\endog, Drer\si:ch211-133n4.4, Drer\LOC100333474, Drer\LOC103910196" Scer\NUC1 Cele\cps-6 - Mmus\Endog Hsap\ENDOG "viable,fertile" FBgn0028043 l(3)S098105 lethal (3) S098105 http://flybase.org/reports/FBgn0028043 gene - - - "0981/05, l(3)S098105" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028235 l(3)S003220 lethal (3) S003220 http://flybase.org/reports/FBgn0028235 gene - - - "0797/09, 0248/36, 0032/20, 0016/04, l(3)S003220" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0039946 ATbp (A+T)-stretch binding protein http://flybase.org/reports/FBgn0039946 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay transcription, DNA-templated ; GO:0006351 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:Q26635" nucleus ; GO:0005634 | inferred by curator from GO:0006351 "CG17172, ATBP, CG40145, ATbp" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR020683:Ankyrin repeat-containing domain, IPR013087:Zinc finger C2H2-type" CG17172 11-Aug-17 DroID_v2017_08 Drer\gtf3ab Scer\PZF1 - Xtro\klf11 Mmus\Zfp239 Hsap\ZNF229 FBgn0031227 CG3709 - http://flybase.org/reports/FBgn0031227 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR020103 pseudouridine synthase activity ; GO:0009982 | inferred from biological aspect of ancestor with PANTHER:PTN000490775 tRNA pseudouridine synthesis ; GO:0031119 | inferred from biological aspect of ancestor with PANTHER:PTN000490775 - "anon-WO0257455.7, CG3709" "IPR020103:Pseudouridine synthase, catalytic domain" CG3709 11-Aug-17 DroID_v2017_08 Drer\pus10 - Cele\Y48C3A.20 Xtro\pus10 Mmus\Pus10 Hsap\PUS10 viable DRSC00629 K -0.770852368 0.174641344 0.112657422 -0.169489653 -1.562865549 -0.19446947 FBgn0051693 CG31693 - http://flybase.org/reports/FBgn0051693 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004680 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004680 "BcDNA:GH25177, CG31693" IPR004680:Citrate transporter-like domain CG31693 11-Aug-17 DroID_v2017_08 Drer\oca2 - Cele\srh-98 Xtro\oca2 Mmus\Oca2 Hsap\OCA2 viable FBgn0040870 CG12454 - http://flybase.org/reports/FBgn0040870 protein_coding_gene - - - CG12454 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036547 CG17032 - http://flybase.org/reports/FBgn0036547 protein_coding_gene - - - CG17032 - CG17032 11-Aug-17 DroID_v2017_08 - - Cele\pqn-75 - - - viable FBgn0264564 CR43936 - http://flybase.org/reports/FBgn0264564 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43936, CR43936" - CR43936 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052794 CG32794 - http://flybase.org/reports/FBgn0052794 protein_coding_gene - - - CG32794 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC24423 EK -0.224904712 1.101181603 2.568057973 -0.36617677 -0.053480751 1.660054052 FBgn0000527 e ebony http://flybase.org/reports/FBgn0000527 - protein_coding_gene beta-alanyl-dopamine synthase activity ; GO:0003833 | inferred from direct assay beta-alanyl-dopamine synthase activity ; GO:0003833 | inferred from mutant phenotype beta-alanyl-dopamine synthase activity ; GO:0003833 | traceable author statement regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from genetic interaction with Ask1 histamine metabolic process ; GO:0001692 | inferred from mutant phenotype melanin biosynthetic process from tyrosine ; GO:0006583 | traceable author statement cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype inferred from genetic interaction with y negative regulation of melanin biosynthetic process ; GO:0048022 | inferred from mutant phenotype pigment metabolic process ; GO:0042440 | traceable author statement developmental pigmentation ; GO:0048066 | traceable author statement regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | non-traceable author statement adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype dopamine metabolic process ; GO:0042417 | inferred from direct assay chitin-based cuticle sclerotization ; GO:0007593 | inferred from mutant phenotype amino acid adenylylation by nonribosomal peptide synthase ; GO:0043042 | inferred from direct assay locomotor rhythm ; GO:0045475 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "ebony, CG3331, e" "IPR000873:AMP-dependent synthetase/ligase, IPR009081:Phosphopantetheine binding ACP domain, IPR020845:AMP-binding, conserved site" CG3331 11-Aug-17 DroID_v2017_08 Drer\aasdh Scer\LYS2 "Cele\W09D6.1, Cele\Y66D12A.14" Xtro\aasdh Mmus\Aasdh Hsap\AASDH " adult stage , larval stage | third instar , embryonic stage -- adult stage " " adult brain

, lamina

, ventral nerve cord | restricted

, larval brain | restricted

, thoracico-abdominal ganglion

, medulla

" "visible,recessive,locomotor rhythm defective,body color defective,neurophysiology defective,visual behavior defective,wild-type,optomotor response defective,viable,semidominant,reduced,heat stress response defective" "trident,adult cuticle,wing,synaptic vesicle,photoreceptor cell,embryonic/larval spiracle,retina,mesothoracic tergum" FBgn0000478 DNase2 Deoxyribonuclease 2 http://flybase.org/reports/FBgn0000478 - gene - - - "DNase2, dnase2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039836 CG1750 - http://flybase.org/reports/FBgn0039836 protein_coding_gene methionyl-tRNA formyltransferase activity ; GO:0004479 | inferred from electronic annotation with InterPro:IPR005794 "biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR002376, InterPro:IPR005793 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA ; GO:0071951 | inferred from electronic annotation with InterPro:IPR005794" - CG1750 "IPR002376:Formyl transferase, N-terminal, IPR005793:Formyl transferase, C-terminal, IPR005794:Methionyl-tRNA formyltransferase, IPR011034:Formyl transferase, C-terminal-like" CG1750 11-Aug-17 DroID_v2017_08 Drer\mtfmt "Scer\FMT1, Scer\ADE8" Cele\alh-3 Xtro\mtfmt Mmus\Mtfmt "Hsap\GART, Hsap\MTFMT" DRSC15240 IE 3.230558066 0.826541851 2.519156785 -0.80312832 -0.269521837 0.001367694 FBgn0267503 2SrRNA:CR45843 2S ribosomal RNA:CR45843 http://flybase.org/reports/FBgn0267503 rRNA_gene - - - "2SrRNA:CR45843, CR45843" - CR45843 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062588 Mod(var)1650 Mod(var)1650 http://flybase.org/reports/FBgn0062588 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1650, Mod(var)1650" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0045967 Tabor\sORF Tabor element sORF http://flybase.org/reports/FBgn0045967 transposable_element_gene - - - "Pilgrim\sORF, Tabor\sORF" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259230 lectin-22C lectin-22C http://flybase.org/reports/FBgn0259230 protein_coding_gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - "CG15378, AC004716a, AC 004716A, lectin-22C, CG42295" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG42295 11-Aug-17 DroID_v2017_08 "Drer\colec11, Drer\LOC101884413, Drer\acanb, Drer\clec3a" - Cele\clec-178 Xtro\clec3a "Mmus\Bcan, Mmus\Acan, Mmus\Clec3a, Mmus\Vcan, Mmus\Colec11" "Hsap\CLEC3A, Hsap\ACAN, Hsap\VCAN, Hsap\BCAN, Hsap\COLEC11" FBgn0281845 BG02222 - http://flybase.org/reports/FBgn0281845 gene - - - BG02222 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004609 NaDg beta N-acetyl D-glucosaminidase http://flybase.org/reports/FBgn0004609 - gene beta-N-acetylglucosaminidase activity ; GO:0016231 | inferred from direct assay cuticle chitin catabolic process ; GO:0006036 | inferred from direct assay - "GlcNAc'ase, HEXOS-1, NaDg" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259740 CG42394 - http://flybase.org/reports/FBgn0259740 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42394 - CG42394 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014076 Vm32E Vitelline membrane 32E http://flybase.org/reports/FBgn0014076 "FBgn0003981, FBgn0003982" protein_coding_gene structural constituent of vitelline membrane ; GO:0008316 | inferred from mutant phenotype vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "VM32E, CG16874, VMP32E, Vm32Ec, Vm32Ea, Vm3, Vm32E, VM321" IPR013135:Vitelline membrane cysteine-rich domain CG16874 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage | female , adult stage && oogenesis stage | stage S10 " " organism

, follicle cell

" "viable,fertile" DRSC03474 E 0.801598598 -0.123650084 2.282082291 -0.942289365 -0.739870786 -0.966476544 FBgn0024676 l(2)k00312 lethal (2) k00312 http://flybase.org/reports/FBgn0024676 - gene - - - "3/12, l(2)k00312" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058090 CG40090 - http://flybase.org/reports/FBgn0058090 protein_coding_gene - - - CG40090 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061178 ap::Bx ap::Bx http://flybase.org/reports/FBgn0061178 engineered_fusion_gene - - - ap::Bx - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing margin,ectopic,wing,ventral compartment,wing vein,wing vein L5,posterior crossvein,dorsal compartment,supernumerary,wing disc" FBgn0060563 l(3)S096703 lethal (3) S096703 http://flybase.org/reports/FBgn0060563 gene - - - "0967/03, l(3)S096703" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0035787 CG8543 - http://flybase.org/reports/FBgn0035787 protein_coding_gene - - - CG8543 IPR022727:Pupal cuticle protein C1 CG8543 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030583 CG14410 - http://flybase.org/reports/FBgn0030583 protein_coding_gene - - - CG14410 - CG14410 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0262790 CG43171 - http://flybase.org/reports/FBgn0262790 protein_coding_gene - - - "CG43171, MIP03715, MIP03715_ORF_1" - CG43171 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003555 su(dpy[ov]) suppressor of dumpy[oblique-vortex] http://flybase.org/reports/FBgn0003555 - gene - - - "su(dp[ov]), su(dp), su(dpy[ov])" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0051579 tRNA:Ala-AGC-2-7 transfer RNA:Alanine-AGC 2-7 http://flybase.org/reports/FBgn0051579 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna15-AlaAGC, tRNA:A:AGC:AE002708-c, CR31579, tRNA[[Ala]], chr3R.trna21-AlaAGC, tRNA-Ala-AGC-2-7, tRNA:Ala-AGC-2-7, tRNA:CR31579, GCU" - CR31579 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034681 CG9308 - http://flybase.org/reports/FBgn0034681 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence model transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR009038 Golgi vesicle transport ; GO:0048193 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from sequence model "CG9308, p24" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG9308 11-Aug-17 DroID_v2017_08 Drer\tmed2 "Scer\ERP3, Scer\ERP2, Scer\ERP4, Scer\EMP24" "Cele\C26C6.9, Cele\Y73B6BL.36, Cele\sel-9" Xtro\tmed2 "Mmus\Gm10698, Mmus\Tmed2" Hsap\TMED2 "viable,visible,partially lethal - majority die" trichogen cell DRSC28962 K 0.19099717 -0.043049805 -0.621223135 0.258237755 1.64036442 1.255758184 FBgn0259660 B0499 - http://flybase.org/reports/FBgn0259660 gene - - - B0499 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible" wing vein FBgn0030396 CG2556 - http://flybase.org/reports/FBgn0030396 protein_coding_gene - - - CG2556 - CG2556 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0044510 mRpS5 mitochondrial ribosomal protein S5 http://flybase.org/reports/FBgn0044510 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR013810 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82675 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82675 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82675 "MRP-S5, CG40049, BcDNA:RE47909, MrpS5, mRpS5" "IPR018192:Ribosomal protein S5, N-terminal, conserved site, IPR000851:Ribosomal protein S5, IPR005324:Ribosomal protein S5, C-terminal, IPR013810:Ribosomal protein S5, N-terminal, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold" CG40049 11-Aug-17 DroID_v2017_08 Drer\mrps5 Scer\MRPS5 Cele\mrps-5 Xtro\mrps5 Mmus\Mrps5 Hsap\MRPS5 FBgn0011152 l(1)Q228 lethal (1) Q228 http://flybase.org/reports/FBgn0011152 FBgn0010210 gene - - - l(1)Q228 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0045065 bst brain storming http://flybase.org/reports/FBgn0045065 gene - brain development ; GO:0007420 | inferred from mutant phenotype - bst - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "ellipsoid body,mushroom body beta-lobe" FBgn0259732 tal-3A tarsal-less 3A http://flybase.org/reports/FBgn0259732 protein_coding_gene molecular_function ; GO:0003674 | no biological data available actin filament organization ; GO:0007015 | inferred from genetic interaction with tal morphogenesis of an epithelium ; GO:0002009 | inferred from genetic interaction with tal cellular_component ; GO:0005575 | no biological data available "Dm3, tal-3A, CG42386, Pep3, ORF3, tal, ORF 3A, pri" - CG42386 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267274 CR45710 - http://flybase.org/reports/FBgn0267274 non_protein_coding_gene - - - CR45710 - CR45710 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028655 anon-35F-36Ab anon-35F-36Ab http://flybase.org/reports/FBgn0028655 gene - - - "anon-35F/36Ab, anon-35F-36Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013281 Inr-Adh Inverse-regulator-Adh http://flybase.org/reports/FBgn0013281 - gene - - - "Inr-A, Inr-Adh" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033050 Pngl PNGase-like http://flybase.org/reports/FBgn0033050 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from direct assay peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity ; GO:0000224 | NOT inferred from direct assay glycoprotein catabolic process ; GO:0006516 | inferred from biological aspect of ancestor with PANTHER:PTN000254236 protein deglycosylation ; GO:0006517 | inferred from biological aspect of ancestor with PANTHER:PTN000254236 glycoprotein catabolic process ; GO:0006516 | inferred from sequence or structural similarity with UniProtKB:Q96IV0 misfolded or incompletely synthesized protein catabolic process ; GO:0006515 | inferred from biological aspect of ancestor with PANTHER:PTN000254236 cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q96IV0 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000254236 "CG7865, PNGase, Pngl, png1" "IPR002931:Transglutaminase-like, IPR006588:Peptide N glycanase, PAW domain, IPR018997:PUB domain, IPR008979:Galactose-binding domain-like" CG7865 11-Aug-17 DroID_v2017_08 Drer\ngly1 Scer\PNG1 Cele\png-1 Xtro\ngly1 Mmus\Ngly1 Hsap\NGLY1 "partially lethal - majority die,viable,recessive,developmental rate defective,male sterile,female sterile,short lived,fertile" FBgn0022111 l(2)k06917 lethal (2) k06917 http://flybase.org/reports/FBgn0022111 - gene - - - l(2)k06917 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027093 ArgRS Arginyl-tRNA synthetase http://flybase.org/reports/FBgn0027093 FBgn0030698 protein_coding_gene "arginine-tRNA ligase activity ; GO:0004814 | inferred from electronic annotation with InterPro:IPR001278, InterPro:IPR005148, InterPro:IPR008909 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001278, InterPro:IPR001412, InterPro:IPR005148, InterPro:IPR008909, InterPro:IPR009080 arginine-tRNA ligase activity ; GO:0004814 | traceable author statement" "arginyl-tRNA aminoacylation ; GO:0006420 | inferred from electronic annotation with InterPro:IPR001278, InterPro:IPR005148, InterPro:IPR008909 arginyl-tRNA aminoacylation ; GO:0006420 | traceable author statement" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR005148 aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement "ArgRS, RRS, CG9020, Aats-arg" "IPR001278:Arginine-tRNA ligase, IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR005148:Arginyl tRNA synthetase N-terminal domain, IPR008909:DALR anticodon binding, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG9020 11-Aug-17 DroID_v2017_08 "Drer\dalrd3, Drer\rars2, Drer\rars" "Scer\YDR341C, Scer\MSR1" "Cele\rars-1, Cele\rars-2" "Xtro\rars2, Xtro\rars" "Mmus\Rars, Mmus\Dalrd3, Mmus\Rars2" "Hsap\RARS, Hsap\RARS2, Hsap\DALRD3" embryonic stage " embryonic/larval salivary gland

,

ubiquitous " lethal FBgn0000669 fliC flightless C http://flybase.org/reports/FBgn0000669 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fliC - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive,heat sensitive,visible,lethal,maternal effect,female sterile,locomotor behavior defective,flight defective,behavior defective" FBgn0039648 CG14515 - http://flybase.org/reports/FBgn0039648 protein_coding_gene - - - CG14515 IPR002861:Reeler domain CG14515 11-Aug-17 DroID_v2017_08 "Drer\zgc:163022, Drer\si:dkey-251i10.2, Drer\si:ch73-14h1.2, Drer\frrs1a, Drer\frrs1b" - "Cele\F23B12.4, Cele\C05D12.1" - Mmus\Frrs1 Hsap\FRRS1 FBgn0261818 CG42760 - http://flybase.org/reports/FBgn0261818 protein_coding_gene - - - CG42760 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262846 CG43210 - http://flybase.org/reports/FBgn0262846 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43210, ORF2" - CG43210 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000316 cin cinnamon http://flybase.org/reports/FBgn0000316 FBgn0026665 protein_coding_gene molybdopterin molybdotransferase activity ; GO:0061599 | inferred from biological aspect of ancestor with PANTHER:PTN000022760 molybdopterin adenylyltransferase activity ; GO:0061598 | inferred from biological aspect of ancestor with PANTHER:PTN000022760 embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement molybdopterin cofactor biosynthetic process ; GO:0032324 | inferred from biological aspect of ancestor with PANTHER:PTN000022759 Mo-molybdopterin cofactor biosynthetic process ; GO:0006777 | inferred from biological aspect of ancestor with PANTHER:PTN000022760 molybdenum incorporation into molybdenum-molybdopterin complex ; GO:0018315 | inferred from biological aspect of ancestor with PANTHER:PTN000022760 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000022759 "EG:BACR37P7.3, CG2945, l(1)G0142, fs(1)M50, l(1)1Ae, cin, CIN" "IPR001453:MoaB/Mog domain, IPR005110:MoeA, N-terminal and linker domain, IPR005111:MoeA, C-terminal, domain IV, IPR008284:Molybdenum cofactor biosynthesis, conserved site" CG2945 11-Aug-17 DroID_v2017_08 "Drer\gphnb, Drer\LOC103909361, Drer\gphna" - "Cele\moc-2, Cele\moc-1, Cele\lin-46" Xtro\gphn Mmus\Gphn Hsap\GPHN "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,fertile,maternal effect,female sterile,lethal - all die before end of embryonic stage,rescuable maternal effect,eye color defective,some die during embryonic stage,heat sensitive" "pigment cell,egg" FBgn0250849 CG32388 - http://flybase.org/reports/FBgn0250849 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT03632, BcDNA:GH26265, BEST:GH26265, anon-WO0140519.36, CG32388, anon-SAGE:Wang-131" - CG32388 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066095 MSu331 MSu331 http://flybase.org/reports/FBgn0066095 gene - - - MSu331 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085521 CG40813 - http://flybase.org/reports/FBgn0085521 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000472 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000480 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 small-subunit processome assembly ; GO:0034462 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000267771" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 CG40813 "IPR000504:RNA recognition motif domain, IPR034353:ABT1/ESF2, RNA recognition motif" CG40813 11-Aug-17 DroID_v2017_08 Drer\abt1 Scer\ESF2 Cele\F57B10.8 Xtro\abt1 Mmus\Abt1 Hsap\ABT1 FBgn0036059 nudE nudE http://flybase.org/reports/FBgn0036059 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with UniProtKB:Q9CZA6 regulation of microtubule motor activity ; GO:2000574 | inferred from electronic annotation with InterPro:IPR033494 centrosome localization ; GO:0051642 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from genetic interaction with dar1 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from sequence or structural similarity with UniProtKB:Q9CZA6 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype nucleus localization ; GO:0051647 | inferred from mutant phenotype spindle ; GO:0005819 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay spindle pole centrosome ; GO:0031616 | inferred from sequence or structural similarity with UniProtKB:Q9CZA6 spindle envelope ; GO:0070732 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay "nudE, DnudE, CG8104, NudE" "IPR006964:NUDE domain, IPR033494:NUDE family" CG8104 11-Aug-17 DroID_v2017_08 "Drer\filip1l, Drer\ndel1a, Drer\ndel1b, Drer\nde1" - "Cele\nud-2, Cele\T04F8.6" "Xtro\nde1, Xtro\ndel1" "Mmus\Ndel1, Mmus\Nde1" "Hsap\NDE1, Hsap\NDEL1" "viable,visible,body color defective,lethal,recessive,mitotic cell cycle defective" "oocyte,germline clone,trichogen cell,mesothoracic tergum,border follicle cell,somatic clone,condensed chromosome,centrosome,centrosome | supernumerary,spindle,spindle pole,spindle & primary spermatocyte in meiotic metaphase I,centrosome & spermatocyte,nucleus & onion stage spermatid,Nebenkern,condensed chromosomeAC1)" DRSC10962 I 2.09007903 0.507133779 0.603703944 -0.156565923 -0.352377824 0.188493545 FBgn0264287 Su(Mir)1-1A2-2 - http://flybase.org/reports/FBgn0264287 gene - - - Su(Mir)1-1A2-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031690 CG7742 - http://flybase.org/reports/FBgn0031690 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 - CG7742 IPR000195:Rab-GTPase-TBC domain CG7742 11-Aug-17 DroID_v2017_08 Drer\tbc1d19 - - Xtro\tbc1d19 Mmus\Tbc1d19 Hsap\TBC1D19 viable FBgn0030715 Or13a Odorant receptor 13a http://flybase.org/reports/FBgn0030715 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "13a, DOR38, 13F.1, CG12697, Or13a, dOr13a, or13a" "IPR004117:Olfactory receptor, insect" CG12697 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,viable" FBgn0013934 Su(Pc)35CD Su(Pc)35CD http://flybase.org/reports/FBgn0013934 - gene - - - "Su(Pc), E(Pc)35CD, E(Pc)28B, Su(Pc)35CD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050206 tRNA:Trp-CCA-2-3 transfer RNA:Tryptophan-CCA 2-3 http://flybase.org/reports/FBgn0050206 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "CR30206, AE002575.trna14-TrpCCA, tRNA:W:CCA:AE002575-d, chr2R.trna58-TrpCCA, tRNA-Trp-CCA-2-3, tRNA:Trp-CCA-2-3, tRNA:CR30206, UGG" - CR30206 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014998 tlr-2 tld-related-2 http://flybase.org/reports/FBgn0014998 - gene - - cellular_component ; GO:0005575 | no biological data available "tlr, tlr-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013283 Jhbp-63 Juvenile hormone binding protein - 63kD http://flybase.org/reports/FBgn0013283 - gene - - - Jhbp-63 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037281 CG1277 - http://flybase.org/reports/FBgn0037281 protein_coding_gene - - - CG1277 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005422 l(1)adl11 lethal (1) adl11 http://flybase.org/reports/FBgn0005422 - gene - - - "l(1)adl-11, l(1)adl11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,heat sensitive,lethal" FBgn0002145 l(2)K483 lethal (2) K483 http://flybase.org/reports/FBgn0002145 - gene - - - l(2)K483 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037012 Rcd2 Reduction in Cnn dots 2 http://flybase.org/reports/FBgn0037012 protein_coding_gene - centriole replication ; GO:0007099 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "CT15369, Rcd2, CG4786" IPR001007:VWFC domain CG4786 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-37e10.2, Drer\si:dkey-266m15.6, Drer\LOC100147849, Drer\otogl, Drer\ch1073-291c23.1, Drer\nell2a, Drer\si:ch211-252f13.5, Drer\scospondin, Drer\crim1, Drer\nell2b, Drer\muc5f, Drer\tecta, Drer\fras1" - "Cele\F19C6.3, Cele\crm-1" "Xtro\zan, Xtro\LOC100497909, Xtro\tecta.1, Xtro\LOC100492852, Xtro\kcp, Xtro\fras1, Xtro\LOC100485197" "Mmus\Nell1, Mmus\Nell2, Mmus\Tecta, Mmus\Muc5ac, Mmus\9530053A07Rik, Mmus\Muc6, Mmus\Sspo, Mmus\Muc5b, Mmus\Kcp, Mmus\Crim1, Mmus\Zan, Mmus\Muc2, Mmus\Otogl, Mmus\Vwce, Mmus\Fcgbp, Mmus\Fras1" "Hsap\NELL2, Hsap\FRAS1, Hsap\MUC6, Hsap\CRIM1, Hsap\OTOGL, Hsap\TECTA, Hsap\VWCE, Hsap\MUC2, Hsap\NELL1, Hsap\MUC5B" "viable,fertile" DRSC11756 IEK 1.063383419 -2.281567593 0.719574409 -1.509769336 2.529112857 0.727687531 FBgn0053366 5SrRNA:CR33366 5SrRNA:CR33366 http://flybase.org/reports/FBgn0053366 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33366, 5SrRNA:CR33366" - CR33366 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067087 JK1285 JK1285 http://flybase.org/reports/FBgn0067087 gene - - - JK1285 - - 11-Aug-17 DroID_v2017_08 - - - - - - neurophysiology defective FBgn0028619 l(2)34Ec lethal (2) 34Ec http://flybase.org/reports/FBgn0028619 gene - - - l(2)34Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086047 snoRNA:Me18S-G894 - http://flybase.org/reports/FBgn0086047 snoRNA_gene - - - "snoRNA:Me18S-G894, Me18S-Gm894, CR34676" - CR34676 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039964 CG18246 - http://flybase.org/reports/FBgn0039964 protein_coding_gene - - - CG18246 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038512 CG14330 - http://flybase.org/reports/FBgn0038512 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14330 - CG14330 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030164 CG1889 - http://flybase.org/reports/FBgn0030164 protein_coding_gene chitin binding ; GO:0008061 | inferred from sequence or structural similarity with HGNC:25922 G-protein coupled receptor binding ; GO:0001664 | inferred from sequence or structural similarity with HGNC:3623 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with HGNC:3623 membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:25922 "CG1889, AAF46536, AAN09619, FBpp0071344, FBpp0071343" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG1889 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-110a20.3, Drer\angptl5, Drer\angpt4, Drer\fgl1, Drer\zgc:194887, Drer\angptl2a, Drer\fgl2b, Drer\zgc:173915, Drer\angpt2a, Drer\angptl3, Drer\angptl6, Drer\si:ch1073-110a20.1, Drer\zgc:171687, Drer\wu:fj11g02, Drer\angptl7, Drer\angpt2b, Drer\angptl1a, Drer\si:ch1073-110a20.2, Drer\angptl2b, Drer\si:ch211-157b11.8, Drer\tnw, Drer\si:zfos-2330d3.1, Drer\LOC100007488, Drer\tnc, Drer\fibcd1, Drer\tnxba, Drer\angptl4, Drer\fgb, Drer\si:ch211-287a12.9, Drer\si:zfos-2330d3.3, Drer\si:dkeyp-51b7.3, Drer\fgl2a, Drer\LOC555374, Drer\zmp:0000000846, Drer\tnr, Drer\fgg, Drer\si:ch211-203k16.3, Drer\si:zfos-2330d3.6, Drer\si:zfos-2330d3.8, Drer\fga, Drer\angpt1, Drer\mfap4" - "Cele\Y26D4A.12, Cele\C18E9.7, Cele\ZC504.1, Cele\let-805, Cele\W05B2.2, Cele\T15B7.1, Cele\ensh-1, Cele\eea-1, Cele\Y69H2.10, Cele\K10D3.4, Cele\Y69H2.3, Cele\Y43C5A.2, Cele\C08G9.2" "Xtro\angptl2, Xtro\tnc, Xtro\fcn3, Xtro\fgg, Xtro\fcn2, Xtro\angpt4, Xtro\LOC100491105, Xtro\mfap4, Xtro\tnxb, Xtro\fibcd1, Xtro\angpt1, Xtro\angptl3, Xtro\fgb, Xtro\fgl2, Xtro\angptl4, Xtro\tnr, Xtro\LOC100488177, Xtro\fga, Xtro\fgl1, Xtro\fcn1, Xtro\angptl5, Xtro\LOC100497330, Xtro\tnn" "Mmus\Angpt2, Mmus\Angptl6, Mmus\Angptl7, Mmus\Angptl4, Mmus\Tnr, Mmus\Fcnb, Mmus\Angptl2, Mmus\Fcna, Mmus\Tnxb, Mmus\Fga, Mmus\Tnc, Mmus\Angptl1, Mmus\Mfap4, Mmus\Fgg, Mmus\Angpt4, Mmus\Fgl1, Mmus\Angpt1, Mmus\Fgl2, Mmus\Tnn, Mmus\Fibcd1, Mmus\Angptl3, Mmus\Fgb" "Hsap\FCN2, Hsap\FCN3, Hsap\ANGPTL1, Hsap\ANGPTL2, Hsap\TNC, Hsap\ANGPT4, Hsap\FGL1, Hsap\ANGPT1, Hsap\FGA, Hsap\TNN, Hsap\TNXB, Hsap\FCN1, Hsap\FGL2, Hsap\ANGPTL4, Hsap\ANGPTL5, Hsap\ANGPTL7, Hsap\FGB, Hsap\ANGPTL3, Hsap\TNR, Hsap\FIBCD1, Hsap\ANGPTL6, Hsap\ANGPT2, Hsap\MFAP4, Hsap\FGG" viable FBgn0041767 anon-d43 anon-d43 http://flybase.org/reports/FBgn0041767 gene - - - "d43, anon-d43" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030829 CG12998 - http://flybase.org/reports/FBgn0030829 protein_coding_gene - - - "CT32204, BcDNA:RH61745, CG12998" - CG12998 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013307 Odc1 Ornithine decarboxylase 1 http://flybase.org/reports/FBgn0013307 FBgn0002984 protein_coding_gene ornithine decarboxylase activity ; GO:0004586 | inferred from biological aspect of ancestor with PANTHER:PTN000159726 putrescine biosynthetic process from ornithine ; GO:0033387 | inferred from biological aspect of ancestor with PANTHER:PTN000159726 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000159726 "dodc1, CG8721, Odc1, Odc-1" "IPR000183:Ornithine/DAP/Arg decarboxylase, IPR002433:Ornithine decarboxylase, IPR009006:Alanine racemase/group IV decarboxylase, C-terminal, IPR029066:PLP-binding barrel, IPR022643:Orn/DAP/Arg decarboxylase 2, C-terminal, IPR022644:Orn/DAP/Arg decarboxylase 2, N-terminal, IPR022653:Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site, IPR022657:Orn/DAP/Arg decarboxylase 2, conserved site" CG8721 11-Aug-17 DroID_v2017_08 "Drer\azin1b, Drer\azin1a, Drer\odc1" Scer\SPE1 Cele\odc-1 "Xtro\azin2, Xtro\azin1, Xtro\odc1" "Mmus\Gm853, Mmus\Odc1, Mmus\Azin2, Mmus\Azin1" "Hsap\ODC1, Hsap\AZIN1, Hsap\AZIN2" "delayed aging,memory defective,viable,visible,body color defective" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0001854 l(1)tsUC32 lethal (1) tsUC32 http://flybase.org/reports/FBgn0001854 - gene - - - l(1)tsUC32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0029878 Pat1 Protein interacting with APP tail-1 http://flybase.org/reports/FBgn0029878 protein_coding_gene - pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype regulation of microtubule-based movement ; GO:0060632 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with NCBI_gi:3986405 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with NCBI_gi:3986405 kinesin complex ; GO:0005871 | inferred from physical interaction with Khc inferred from physical interaction with Klc "CG10695, PAT1, Pat1, pat1" "IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain" CG10695 11-Aug-17 DroID_v2017_08 "Drer\nphp3, Drer\ttc19, Drer\klc3, Drer\appbp2, Drer\klc1a, Drer\klc4, Drer\klc2" - Cele\klc-1 "Xtro\appbp2, Xtro\ttc19, Xtro\klc1, Xtro\nphp3" "Mmus\Nphp3, Mmus\Klc3, Mmus\Appbp2, Mmus\Klc2, Mmus\Klc4, Mmus\Ttc19, Mmus\Klc1" "Hsap\KLC3, Hsap\TTC19, Hsap\KLC4, Hsap\KLC2, Hsap\APPBP2, Hsap\KLC1, Hsap\NPHP3" "viable,fertile" FBgn0062576 Mod(var)E113 Mod(var)E113 http://flybase.org/reports/FBgn0062576 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E113, Mod(var)E113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0026721 fat-spondin fat-spondin http://flybase.org/reports/FBgn0026721 - protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - extracellular region ; GO:0005576 | inferred from direct assay "CG6953, CT21501, fat-spondin, Fat-spondin, Dmel_CG6953" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR002861:Reeler domain, IPR009465:Spondin, N-terminal, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG6953 11-Aug-17 DroID_v2017_08 "Drer\spon1b, Drer\spon1a" - Cele\spon-1 Xtro\spon1 "Mmus\Spon2, Mmus\Spon1" "Hsap\ADAMTS9, Hsap\SPON2, Hsap\SPON1" viable FBgn0000891 fs(1)M89 female sterile (1) M89 http://flybase.org/reports/FBgn0000891 - gene - - - fs(1)M89 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0015421 l(1)17Ag lethal (1) 17Ag http://flybase.org/reports/FBgn0015421 - gene - - - l(1)17Ag - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261792 snRNP-U1-C small ribonucleoprotein particle U1 subunit C http://flybase.org/reports/FBgn0261792 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000690, InterPro:IPR003604, InterPro:IPR013085 pre-mRNA 5'-splice site binding ; GO:0030627 | inferred from biological aspect of ancestor with PANTHER:PTN001259483" "spliceosomal snRNP assembly ; GO:0000387 | inferred from electronic annotation with InterPro:IPR017340 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA 5'-splice site recognition ; GO:0000395 | inferred from biological aspect of ancestor with PANTHER:PTN001259483 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004289" commitment complex ; GO:0000243 | inferred from biological aspect of ancestor with PANTHER:PTN001259483 prespliceosome ; GO:0071010 | inferred from biological aspect of ancestor with PANTHER:PTN001259483 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from direct assay U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity with SGD:S000004289 U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN001259483 nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleus ; GO:0005634 | inferred from direct assay "snRNP-U1-C, U1C, BcDNA:RH29440, snRNP-U1, CG5454, C, snRNPC, dU1-C, SmC" "IPR013087:Zinc finger C2H2-type, IPR000690:Matrin/U1-C, C2H2-type zinc finger, IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013085:U1-C, C2H2-type zinc finger, IPR017340:U1 small nuclear ribonucleoprotein C" CG5454 11-Aug-17 DroID_v2017_08 Drer\snrpc Scer\YHC1 Cele\F08B4.7 "Xtro\snrpc, Xtro\zmat5" "Mmus\Snrpc, Mmus\Zmat5" "Hsap\SNRPC, Hsap\ZMAT5" DRSC15804 I 4.689201368 1.488234775 -0.191911559 0.703537372 -0.20867155 0.11260908 FBgn0065885 l(2)SH0228 lethal (2) SH0228 http://flybase.org/reports/FBgn0065885 gene - - - "l(2)SH0228, l(2)SH2 0228" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000175 bf brief http://flybase.org/reports/FBgn0000175 - gene - - - bf - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable,female fertile,poor,visible" macrochaeta FBgn0002281 l(3)73Af lethal (3) 73Af http://flybase.org/reports/FBgn0002281 - gene - - - "l(3)133.52, l(3)73Af" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0265417 CG44329 - http://flybase.org/reports/FBgn0265417 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44329, lincRNA.951" - CG44329 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069206 l(2)46Dh lethal (2) 46Dh http://flybase.org/reports/FBgn0069206 gene - - - l(2)46Dh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0083050 snoRNA:Psi18S-1377b snoRNA:Psi18S-1377b http://flybase.org/reports/FBgn0083050 snoRNA_gene - - - "snoRNA:Psi18S-1377b, Psi18S-1377b, psi18S-1377b, CR34628" - CR34628 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000534 E(ade2) Enhancer of ade2 http://flybase.org/reports/FBgn0000534 - gene - - - E(ade2) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060320 l(3)S147114 lethal (3) S147114 http://flybase.org/reports/FBgn0060320 gene - - - "1475/06, 1471/14, l(3)S147506a, l(3)S147114" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0033900 CysRS-m "Cysteinyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0033900 protein_coding_gene cysteine-tRNA ligase activity ; GO:0004817 | inferred from electronic annotation with InterPro:IPR015803 cysteine-tRNA ligase activity ; GO:0004817 | traceable author statement ATP binding ; GO:0005524 | inferred from biological aspect of ancestor with PANTHER:PTN000095308 cysteinyl-tRNA aminoacylation ; GO:0006423 | inferred from electronic annotation with InterPro:IPR015803 cysteinyl-tRNA aminoacylation ; GO:0006423 | traceable author statement mitochondrion ; GO:0005739 | traceable author statement "CG8257, CysRS-m" "IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR015803:Cysteine-tRNA ligase, IPR032678:tRNA synthetases class I, catalytic domain, IPR024909:Cysteinyl-tRNA synthetase/mycothiol ligase" CG8257 11-Aug-17 DroID_v2017_08 "Drer\cars2, Drer\cars" Scer\YNL247W Cele\cars-1 "Xtro\cars2, Xtro\cars" "Mmus\Cars2, Mmus\Cars" "Hsap\CARS, Hsap\CARS2" "viable,visible" trichogen cell FBgn0060314 l(3)S147703 lethal (3) S147703 http://flybase.org/reports/FBgn0060314 gene - - - "1477/03, l(3)S147703" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable" FBgn0065970 l(2)45Da lethal (2) 45Da http://flybase.org/reports/FBgn0065970 gene - - - l(2)45Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037520 CG18268 - http://flybase.org/reports/FBgn0037520 protein_coding_gene - - - CG18268 "IPR011021:Arrestin-like, N-terminal, IPR014756:Immunoglobulin E-set" CG18268 11-Aug-17 DroID_v2017_08 "Drer\arrdc3a, Drer\txnipb, Drer\zgc:110353, Drer\LOC799768, Drer\arrdc1b, Drer\arrdc2, Drer\si:ch211-130m23.2, Drer\arrdc1a, Drer\zgc:110626, Drer\txnipa, Drer\arrdc3b" "Scer\ROD1, Scer\ALY2, Scer\RIM8, Scer\ROG3, Scer\LDB19, Scer\ART5, Scer\CSR2, Scer\ECM21, Scer\ALY1" "Cele\rnh-1.2, Cele\arrd-23, Cele\arrd-14, Cele\arrd-25, Cele\arrd-3, Cele\arrd-15, Cele\arrd-9, Cele\arrd-11, Cele\arrd-12, Cele\arrd-16, Cele\arrd-8, Cele\arrd-13, Cele\arrd-4, Cele\arrd-6, Cele\arrd-22, Cele\arrd-27, Cele\arrd-2, Cele\arrd-19, Cele\arrd-24, Cele\arrd-1, Cele\arrd-7, Cele\arrd-18, Cele\arrd-5" "Xtro\txnip, Xtro\arrdc2, Xtro\arrdc4, Xtro\arrdc3" "Mmus\Arrdc5, Mmus\Arrdc4, Mmus\Arrdc1, Mmus\Arrdc2, Mmus\Arrdc3, Mmus\Txnip" "Hsap\ARRDC3, Hsap\ARRDC4, Hsap\ARRDC5, Hsap\ARRDC2, Hsap\TXNIP, Hsap\ARRDC1" viable FBgn0036133 CG7638 - http://flybase.org/reports/FBgn0036133 protein_coding_gene - - - CG7638 IPR019395:Transmembrane protein 161A/B CG7638 11-Aug-17 DroID_v2017_08 "Drer\tmem161a, Drer\tmem161b" - Cele\Y87G2A.13 "Xtro\tmem161a, Xtro\tmem161b" "Mmus\Tmem161b, Mmus\Tmem161a" "Hsap\TMEM161B, Hsap\TMEM161A" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC22684 IK 2.884542988 0.755356983 1.302120481 1.33804857 0.993360314 1.543866353 FBgn0052767 CG32767 - http://flybase.org/reports/FBgn0052767 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "i7, LD34931, CG5086, CG5113, BcDNA:GM08530, CG32767" "IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG32767 11-Aug-17 DroID_v2017_08 "Drer\LOC101883087, Drer\znfl2a" - Cele\blmp-1 - "Mmus\Zscan26, Mmus\Zfp281, Mmus\Zfp687, Mmus\Zfp148" "Hsap\ZFP91, Hsap\ZNF592, Hsap\ZNF692" "viable,visible" trichogen cell DRSC18386 IEK 2.425877083 1.682998704 0.553123392 -1.80458811 1.799204937 2.693785 FBgn0052740 tRNA:Phe-GAA-1-2 transfer RNA:Phenylalanine-GAA 1-2 http://flybase.org/reports/FBgn0052740 tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "AE002566.trna5-PheGAA, tRNA:F:GAA:AE002566-b, CR32740, chrX.trna25-PheGAA, tRNA-Phe-GAA-1-2, tRNA:Phe-GAA-1-2, tRNA:CR32740, UUC" - CR32740 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032168 CG13126 - http://flybase.org/reports/FBgn0032168 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR015324 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR015324 - "anon-WO0118547.208, CG13126" "IPR015324:Ribosomal protein Rsm22, bacterial-type, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG13126 11-Aug-17 DroID_v2017_08 Drer\mettl17 Scer\RSM22 Cele\F32A7.4 Xtro\mettl17 Mmus\Mettl17 Hsap\METTL17 FBgn0261357 CG42634 - http://flybase.org/reports/FBgn0261357 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42634, CG15149" - CG42634 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028021 l(3)S104018b lethal (3) S104018b http://flybase.org/reports/FBgn0028021 gene - - - "1040/18, l(3)S104018, l(3)S104018b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025484 l(3)Ax18 lethal (3) Ax18 http://flybase.org/reports/FBgn0025484 - gene - - - "Ax18, l(3)Ax18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028520 CG4891 - http://flybase.org/reports/FBgn0028520 protein_coding_gene - - - "DS04095.1, BG:DS04095.1, CG4891" - CG4891 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030501 BthD BthD selenoprotein http://flybase.org/reports/FBgn0030501 protein_coding_gene - determination of adult lifespan ; GO:0008340 | inferred from direct assay larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype response to redox state ; GO:0051775 | non-traceable author statement cell redox homeostasis ; GO:0045454 | traceable author statement embryo development ; GO:0009790 | inferred from direct assay salivary gland boundary specification ; GO:0007432 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG11177, dselM, BthD, dselH, dSelH, SelH" "IPR011893:Selenoprotein, Rdx type" CG11177 11-Aug-17 DroID_v2017_08 Drer\cenpa - - - Mmus\Selenoh Hsap\SELENOH "decreased cell size,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval salivary gland,mesothoracic tergum" FBgn0002342 l(3)87Bk lethal (3) 87Bk http://flybase.org/reports/FBgn0002342 - gene - - - "l(3)ck23, l(3)87Bk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0002127 l(2)IP85 lethal (2) IP85 http://flybase.org/reports/FBgn0002127 - gene - - - l(2)IP85 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,embryonic/first instar larval cuticle" FBgn0022242 l(2)k02205 lethal (2) k02205 http://flybase.net/reports/FBgn0022242.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0053402 5SrRNA:CR33402 5SrRNA:CR33402 http://flybase.org/reports/FBgn0053402 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33402, 5SrRNA:CR33402" - CR33402 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011910 tRNA:Leu-CAA-1-1 transfer RNA:Leucine-CAA 1-1 http://flybase.org/reports/FBgn0011910 "FBgn0003789, FBgn0050248, FBgn0050508, FBgn0060162" tRNA_gene UUG codon-amino acid adaptor activity ; GO:0033404 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033404 cytosol ; GO:0005829 | inferred by curator from GO:0033404 "tRNA[Leu], CR30508, DtL[b], leu-b, AE002787.trna41-LeuCAA, tRNA:L:CAA:AE002787-b, tRNA:leu3:49Fb, CR30248, tRNA[LEU], chr2R.trna23-LeuCAA, tRNA-Leu-CAA-1-1, tRNA:Leu-CAA-1-1, tRNA:L3:49Fb, UUG" - CR30508 11-Aug-17 DroID_v2017_08 - - - - - - male sterile spermatozoon FBgn0060855 l(3)S048219b lethal (3) S048219b http://flybase.org/reports/FBgn0060855 gene - - - "0482/19, l(3)S048219b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0083282 E(smoDN)219 Enhancer of smoDN 219 http://flybase.org/reports/FBgn0083282 gene - - - E(smoDN)219 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038784 CG4362 - http://flybase.org/reports/FBgn0038784 protein_coding_gene - - - CG4362 "IPR004302:Cellulose/chitin-binding protein, N-terminal" CG4362 11-Aug-17 DroID_v2017_08 - - - - Mmus\Defb46 - "viable,fertile" FBgn0066360 l(1)8Da lethal (1) 8Da http://flybase.org/reports/FBgn0066360 gene - - - l(1)8Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038611 CG14309 - http://flybase.org/reports/FBgn0038611 protein_coding_gene "hydrolase activity, acting on glycosyl bonds ; GO:0016798 | inferred from electronic annotation with InterPro:IPR005199" - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005199 lipid particle ; GO:0005811 | inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | inferred from biological aspect of ancestor with PANTHER:PTN001024080 CG14309 "IPR005199:Glycoside hydrolase, family 79" CG14309 11-Aug-17 DroID_v2017_08 "Drer\hpse, Drer\hpse2" - - Xtro\hpse2 "Mmus\Hpse2, Mmus\Hpse" "Hsap\HPSE2, Hsap\HPSE" viable FBgn0050065 CG30065 - http://flybase.org/reports/FBgn0050065 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT19876, CG30065" - CG30065 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052824 CG32824 - http://flybase.org/reports/FBgn0052824 protein_coding_gene - - - "CG18859, CG32824" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260971 CG42594 - http://flybase.org/reports/FBgn0260971 protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" "CG42594, CG32770, CG6952, CG15470, CG32771" "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG42594 11-Aug-17 DroID_v2017_08 "Drer\kcnk2a, Drer\kcnk18, Drer\kcnk1b, Drer\kcnk5b, Drer\kcnk6, Drer\kcnk10b, Drer\kcnk5a, Drer\kcnk7, Drer\kcnk10a, Drer\kcnk1a" Scer\TOK1 "Cele\twk-39, Cele\twk-48" "Xtro\LOC100486031, Xtro\kcnk1, Xtro\kcnk18, Xtro\kcnk16, Xtro\kcnk4, Xtro\kcnk2, Xtro\kcnk10, Xtro\kcnk6, Xtro\kcnk5, Xtro\kcnk7" "Mmus\Kcnk10, Mmus\Kcnk16, Mmus\Kcnk5, Mmus\Kcnk4, Mmus\Kcnk7, Mmus\Kcnk6, Mmus\Kcnk18, Mmus\Kcnk2, Mmus\Kcnk1" "Hsap\KCNK2, Hsap\KCNK16, Hsap\KCNK7, Hsap\KCNK5, Hsap\KCNK10, Hsap\KCNK4, Hsap\KCNK17, Hsap\KCNK6, Hsap\KCNK1, Hsap\KCNK18" DRSC17363 I 2.331603864 -0.262070574 0.128787111 0.28027347 0.049207114 -0.391003505 FBgn0005760 l(1)TK404 lethal (1) TK404 http://flybase.org/reports/FBgn0005760 - gene - - - "l404, l(1)TK404" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0082624 S(CycE[JP])3.4 S(CycE[JP])3.4 http://flybase.org/reports/FBgn0082624 gene - - - "3.4, S(CycE[JP])3.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038846 CG5697 - http://flybase.org/reports/FBgn0038846 protein_coding_gene - - - "BcDNA:RH32180, CG5697" "IPR031984:Solute carrier family 3 member 2, N-terminal domain" CG5697 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260342 GSd033 - http://flybase.org/reports/FBgn0260342 gene - - - GSd033 - - 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve" FBgn0000889 fs(1)M87 female sterile (1) M87 http://flybase.org/reports/FBgn0000889 - gene - - - fs(1)M87 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0266233 CR44928 - http://flybase.org/reports/FBgn0266233 non_protein_coding_gene - - - "CR44928, lincRNA.687" - CR44928 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086915 Mst77F Male-specific transcript 77F http://flybase.org/reports/FBgn0086915 protein_coding_gene - "spermatid nucleus elongation ; GO:0007290 | inferred from mutant phenotype sperm chromatin condensation ; GO:0035092 | inferred from mutant phenotype spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from direct assay" chromatin ; GO:0000785 | inferred from direct assay sperm flagellum ; GO:0036126 | inferred from direct assay microtubule ; GO:0005874 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Mst77F, mst77F, 18c, R1-18c, CG3354, nc3, ms(3)nc3, MST77F" - CG3354 11-Aug-17 DroID_v2017_08 - - - - - - pupal stage&&adult stage "male sterile,viable,fertile,partially lethal - majority die,some die during pupal stage" "nucleus & late spermatidri-79c),chromatin & late spermatidri-79c),spermatid,nucleus & late spermatid,chromatin & late spermatid,nucleus & spermatozoon" FBgn0035867 CG13671 - http://flybase.org/reports/FBgn0035867 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 CG13671 IPR012336:Thioredoxin-like fold CG13671 11-Aug-17 DroID_v2017_08 "Drer\zgc:136472, Drer\zgc:100906, Drer\pdia2, Drer\pdia3, Drer\pdia4, Drer\txndc11, Drer\p4hb, Drer\zgc:77086" "Scer\EUG1, Scer\PDI1" "Cele\pdi-3, Cele\C03H12.1" "Xtro\txndc11, Xtro\p4hb, Xtro\pdia2, Xtro\pdia4, Xtro\pdia3, Xtro\pdilt" "Mmus\P4hb, Mmus\Txndc11, Mmus\Pdia2, Mmus\Pdia3, Mmus\Pdilt, Mmus\Pdia4" "Hsap\PDIA2, Hsap\PDIA3, Hsap\TXNDC11, Hsap\PDIA4, Hsap\P4HB" "viable,fertile" FBgn0043012 AP-2sigma "Adaptor Protein complex 2, sigma subunit" http://flybase.org/reports/FBgn0043012 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR000804 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype synaptic vesicle coating ; GO:0016183 | traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle coating ; GO:0006901 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype synaptic vesicle ; GO:0008021 | traceable author statement coated vesicle ; GO:0030135 | traceable author statement AP-2 adaptor complex ; GO:0030122 | inferred from mutant phenotype "cg6056, CG6056, sigma2, AP-2sigma, AP2, aps2, AP-2 sigma, sigma2-ada, AP2-sigma" "IPR000804:Clathrin adaptor complex, small chain, IPR011012:Longin-like domain, IPR016635:Adaptor protein complex, sigma subunit, IPR027156:AP-2 complex subunit sigma, IPR022775:AP complex, mu/sigma subunit" CG6056 11-Aug-17 DroID_v2017_08 "Drer\arpin, Drer\ap1s3a, Drer\ap1s3b, Drer\ap2s1, Drer\ap1s1" "Scer\APS1, Scer\APS2" "Cele\aps-3, Cele\aps-2, Cele\aps-1" "Xtro\ap2s1, Xtro\ap3s1, Xtro\ap1s3, Xtro\arpin, Xtro\ap3s2, Xtro\ap1s1, Xtro\ap1s2" "Mmus\Ap2s1, Mmus\Ap3s1, Mmus\Ap1s2, Mmus\Ap1s3, Mmus\Ap3s2, Mmus\Arpin" "Hsap\ARPIN, Hsap\AP3S1, Hsap\AP1S2, Hsap\AP1S1, Hsap\AP2S1, Hsap\AP1S3" "neuroanatomy defective,recessive,somatic clone,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,somatic clone,supernumerary,embryonic/larval brain" FBgn0083275 E(smoDN)2577 Enhancer of smoDN 2577 http://flybase.org/reports/FBgn0083275 gene - - - E(smoDN)2577 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083087 hys hyperswirl http://flybase.org/reports/FBgn0083087 gene - determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype - hys - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,short lived,recessive,flight defective" flight muscle & mitochondrial inner membrane FBgn0051880 CG31880 - http://flybase.org/reports/FBgn0051880 protein_coding_gene - - - CG31880 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065763 l(2)SH0476 lethal (2) SH0476 http://flybase.org/reports/FBgn0065763 gene - - - "l(2)SH0476, l(2)SH2 0476" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082987 snoRNA:Psi28S-2444 snoRNA:Psi28S-2444 http://flybase.org/reports/FBgn0082987 snoRNA_gene - - - "snoRNA:Psi28S-2444, psi28s-2444, Psi 28S-2444, CR34546, chr2R:14957975..14958113" - CR34546 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029882 CG3226 - http://flybase.org/reports/FBgn0029882 protein_coding_gene - heart development ; GO:0007507 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "Q9W3Y3, CG3226" "IPR007052:CS domain, IPR007699:SGS domain, IPR008978:HSP20-like chaperone, IPR015120:Siah interacting protein, N-terminal" CG3226 11-Aug-17 DroID_v2017_08 Drer\cacybp Scer\SGT1 "Cele\Y82E9BR.25, Cele\D1054.3" Xtro\cacybp Mmus\Cacybp Hsap\CACYBP viable FBgn0020897 Su(osk)G23 Suppressor of oskar G23 http://flybase.org/reports/FBgn0020897 - gene - - - "G23, Su(osk)G23" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038839 Ktl Kctd12-like http://flybase.org/reports/FBgn0038839 protein_coding_gene - protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 male courtship behavior ; GO:0008049 | inferred from mutant phenotype negative regulation of locomotion involved in locomotory behavior ; GO:0090327 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "CG10830, Ktl" "IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR011333:SKP1/BTB/POZ domain" CG10830 11-Aug-17 DroID_v2017_08 "Drer\kctd4, Drer\kctd12b, Drer\kctd6a, Drer\kctd8, Drer\kctd12.2, Drer\kctd16a, Drer\kctd16b, Drer\kctd12.1, Drer\kctd7, Drer\kctd6b, Drer\kctd14, Drer\kctd15a" - "Cele\F59F3.6, Cele\T23G5.3, Cele\F49H12.3, Cele\K02F6.5, Cele\VM106R.1, Cele\F32B4.5" "Xtro\kctd1, Xtro\kctd6, Xtro\kctd8, Xtro\kctd7, Xtro\kctd15, Xtro\kcnrg, Xtro\kctd12, Xtro\kctd14, Xtro\LOC100124783" "Mmus\Kctd1, Mmus\Kctd18, Mmus\Kctd7, Mmus\Kctd4, Mmus\Kctd12b, Mmus\Kctd12, Mmus\Kctd16, Mmus\Kctd19, Mmus\Kcnrg, Mmus\Kctd21, Mmus\Kctd14, Mmus\Kctd11, Mmus\Kctd8, Mmus\Kctd6, Mmus\Kctd15" "Hsap\KCTD15, Hsap\KCTD6, Hsap\KCTD19, Hsap\KCTD16, Hsap\KCNRG, Hsap\KCTD4, Hsap\KCTD8, Hsap\KCTD1, Hsap\KCTD18, Hsap\KCTD21, Hsap\KCTD11, Hsap\KCTD14, Hsap\KCTD12" viable FBgn0000963 fs(2)eo4 female sterile (2) eo4 http://flybase.org/reports/FBgn0000963 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "fs(2)eoPB6, fs(2)eo-A, fs(2)eo4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male sterile" FBgn0082621 S(CycE[JP])43S1 S(CycE[JP])43S1 http://flybase.org/reports/FBgn0082621 gene - - - "43S1, S(CycE[JP])43S1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266679 CR45169 - http://flybase.org/reports/FBgn0266679 non_protein_coding_gene - - - CR45169 - CR45169 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004118 nAChRbeta2 nicotinic Acetylcholine Receptor beta2 http://flybase.org/reports/FBgn0004118 - protein_coding_gene acetylcholine-gated cation channel activity ; GO:0022848 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006029, InterPro:IPR006201 response to insecticide ; GO:0017085 | inferred from mutant phenotype synaptic transmission, cholinergic ; GO:0007271 | inferred from expression pattern" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006201 postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity" "CG6798, nAcRbeta-96A, nAChR, SBD, nAcr96Ac, sbd, nAcRs, Acr96Ac, beta[[2]], AcrF, nAcRbeta, beta2, Dbeta2, nAChRbeta2, nACRbeta, nACR beta 96A, nAChR-beta96A" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG6798 11-Aug-17 DroID_v2017_08 "Drer\chrnb3b, Drer\LOC101882451, Drer\chrnb1, Drer\chrnb2b, Drer\si:ch211-256e16.4, Drer\chrne, Drer\chrna2b, Drer\LOC798522, Drer\htr3a, Drer\chrna3, Drer\chrnb4, Drer\chrna2a, Drer\chrna10a, Drer\chrna6, Drer\chrna9, Drer\chrnb3a, Drer\chrng, Drer\chrna4b, Drer\chrnb1l, Drer\chrna1, Drer\si:ch211-39a7.1, Drer\chrnd, Drer\chrnb2l, Drer\htr3b, Drer\si:ch73-380n15.2, Drer\chrna5, Drer\chrnb2a" - "Cele\acr-19, Cele\acr-7, Cele\unc-63, Cele\acr-25, Cele\acr-21, Cele\lev-1, Cele\lev-8, Cele\eat-2, Cele\acr-8, Cele\acr-12, Cele\acr-3, Cele\acr-9, Cele\acr-10, Cele\unc-38, Cele\acr-14, Cele\acr-16, Cele\acr-11, Cele\acr-6, Cele\acr-2, Cele\acr-15, Cele\lgc-4" "Xtro\chrna6, Xtro\chrnd, Xtro\chrng, Xtro\chrnb2, Xtro\chrna1, Xtro\chrna7, Xtro\chrnb3, Xtro\chrna5, Xtro\chrna9, Xtro\chrne, Xtro\chrna2, Xtro\chrna1.2" "Mmus\Chrna2, Mmus\Chrna4, Mmus\Chrna9, Mmus\Chrnb1, Mmus\Htr3b, Mmus\Chrnb2, Mmus\Chrna10, Mmus\Chrna5, Mmus\Chrnb4, Mmus\Htr3a, Mmus\Chrna6, Mmus\Chrnb3, Mmus\Chrng, Mmus\Chrna1, Mmus\Chrna7, Mmus\Chrna3, Mmus\Chrnd, Mmus\Chrne" "Hsap\HTR3B, Hsap\HTR3C, Hsap\CHRNB1, Hsap\CHRNA4, Hsap\CHRNG, Hsap\CHRNA1, Hsap\CHRNA2, Hsap\HTR3E, Hsap\CHRND, Hsap\HTR3D, Hsap\CHRNA9, Hsap\CHRNB3, Hsap\CHRNA3, Hsap\CHRNA6, Hsap\CHRNE, Hsap\CHRNA5, Hsap\CHRNB4, Hsap\CHRNB2, Hsap\HTR3A, Hsap\CHRNA10, Hsap\CHRNA7, Hsap\CHRFAM7A" "chemical resistant,viable,visible" "chaeta,supernumerary" FBgn0265881 CR44670 - http://flybase.org/reports/FBgn0265881 non_protein_coding_gene - - - "CR44670, lincRNA.607" - CR44670 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036346 CG11251 - http://flybase.org/reports/FBgn0036346 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011234 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR011234 - CG11251 "IPR011234:Fumarylacetoacetase, C-terminal-related" CG11251 11-Aug-17 DroID_v2017_08 "Drer\fahd2a, Drer\fahd1" Scer\FMP41 Cele\fahd-1 Xtro\fahd2a "Mmus\Fahd1, Mmus\Fahd2a" "Hsap\FAHD1, Hsap\FAHD2A, Hsap\FAHD2B" "viable,planar polarity defective" FBgn0266931 CR45382 - http://flybase.org/reports/FBgn0266931 non_protein_coding_gene - - - CR45382 - CR45382 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267447 CR45797 - http://flybase.org/reports/FBgn0267447 non_protein_coding_gene - - - "CR45797, Mgn94071" - CR45797 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039300 RpS27 Ribosomal protein S27 http://flybase.org/reports/FBgn0039300 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000592, InterPro:IPR011332 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000174285 translation ; GO:0006412 | inferred by curator from GO:0003735 cytoplasmic translation ; GO:0002181 | traceable author statement" ribosome ; GO:0005840 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "CG10423, anon-EST:Posey295, RpS27, Rp S27, Q9VBU9_DROME" "IPR011332:Zinc-binding ribosomal protein, IPR000592:Ribosomal protein S27e, IPR023407:Ribosomal protein S27e, zinc-binding domain" CG10423 11-Aug-17 DroID_v2017_08 "Drer\zgc:136826, Drer\rps27.2, Drer\rps27.1" "Scer\RPS27B, Scer\RPS27A" Cele\rps-27 Xtro\rps27 "Mmus\Rps27l, Mmus\Rps27, Mmus\Rps27rt" "Hsap\RPS27L, Hsap\RPS27" DRSC14244 EK -1.281564695 0.877475399 1.320068678 -2.01867904 1.680337223 3.498688029 FBgn0001536 l(1)14Bb lethal (1) 14Bb http://flybase.org/reports/FBgn0001536 - gene - - - l(1)14Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000574 elyC early C http://flybase.org/reports/FBgn0000574 - gene - - - "ely-C, elyC" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" "embryo,syncytial blastoderm embryo,maternal effect" FBgn0062699 EP1125 EP1125 http://flybase.org/reports/FBgn0062699 gene - - - "EP(X)1125, EP1125" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002703 mei-1029 meiotic 1029 http://flybase.org/reports/FBgn0002703 - gene - - - "1029, mei-1029" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0029053 l(1)G0455 lethal (1) G0455 http://flybase.org/reports/FBgn0029053 gene - - - l(1)G0455 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0001469 l(1)8Aa lethal (1) 8Aa http://flybase.org/reports/FBgn0001469 - gene - - - "l(1)VE709, HC179, l(1)JV69, l(1)8Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "ovariole,germline clone,egg,maternal effect" FBgn0082972 snoRNA:Psi28S-3316a snoRNA:Psi28S-3316a http://flybase.org/reports/FBgn0082972 snoRNA_gene - - - "snoRNA:Psi28S-3316a, Psi28S-3316a, Psi28S-3316, psi28S-3316a, Psi 28S-3316a, CR34547" - CR34547 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264915 CR44106 - http://flybase.org/reports/FBgn0264915 non_protein_coding_gene - - - CR44106 - CR44106 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042149 CG18826 - http://flybase.org/reports/FBgn0042149 protein_coding_gene - - - CG18826 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034657 LBR Lamin B receptor http://flybase.org/reports/FBgn0034657 protein_coding_gene "chromatin binding ; GO:0003682 | inferred from direct assay lamin binding ; GO:0005521 | inferred from physical interaction with UniProtKB:P08928 oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from biological aspect of ancestor with PANTHER:PTN000479179 delta14-sterol reductase activity ; GO:0050613 | NOT inferred from genetic interaction with UniProtKB:P25340" nucleus organization ; GO:0006997 | inferred by curator from GO:0005521 sterol biosynthetic process ; GO:0016126 | inferred from biological aspect of ancestor with PANTHER:PTN000479179 nuclear inner membrane ; GO:0005637 | inferred from direct assay integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000479179 integral component of nuclear inner membrane ; GO:0005639 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay "dLBR, CG17952, LBR" IPR001171:Ergosterol biosynthesis ERG4/ERG24 CG17952 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-429i10.1, Drer\dhcr7, Drer\lbr, Drer\tm7sf2" "Scer\ERG4, Scer\ERG24" Cele\dhcr-7 "Xtro\dhcr7, Xtro\lbr, Xtro\tm7sf2" "Mmus\Tm7sf2, Mmus\Dhcr7, Mmus\Lbr" "Hsap\LBR, Hsap\DHCR7, Hsap\TM7SF2" viable FBgn0039189 CG18528 - http://flybase.org/reports/FBgn0039189 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR004520, InterPro:IPR005225, InterPro:IPR006073 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR004520" tRNA modification ; GO:0006400 | inferred from electronic annotation with InterPro:IPR004520 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR004520 CG18528 "IPR025867:MnmE, helical domain, IPR004520:tRNA modification GTPase MnmE, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031168:TrmE-type guanine nucleotide-binding domain, IPR018948:GTP-binding protein TrmE, N-terminal, IPR006073:GTP binding domain" CG18528 11-Aug-17 DroID_v2017_08 Drer\gtpbp3 Scer\MSS1 "Cele\F46B6.4, Cele\mtcu-1" Xtro\gtpbp3 Mmus\Gtpbp3 Hsap\GTPBP3 viable FBgn0263983 CG43732 - http://flybase.org/reports/FBgn0263983 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Dm_3R:78579, CG43732" - CG43732 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014958 fliN flightless N http://flybase.org/reports/FBgn0014958 - gene - - - fliN - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" FBgn0038194 Cyp6d5 Cyp6d5 http://flybase.org/reports/FBgn0038194 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "cyp6d5, 6d5, CG3050, Cyp6d5, CYP6d5" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG3050 11-Aug-17 DroID_v2017_08 "Drer\tbxas1, Drer\cyp3c1, Drer\cyp3c4, Drer\cyp3a65, Drer\cyp3c3, Drer\cyp3c2" Scer\ERG11 "Cele\cyp-25A6, Cele\cyp-13A6, Cele\cyp-13A2, Cele\cyp-13A8, Cele\cyp-33E2, Cele\cyp-13B2, Cele\cyp-13A3, Cele\cyp-13A10, Cele\cyp-13A4, Cele\cyp-44A1, Cele\cyp-13A7, Cele\cyp-33C3, Cele\cyp-34A4, Cele\cyp-43A1, Cele\cyp-13A11, Cele\cyp-13B1, Cele\cyp-13A12, Cele\cyp-25A2, Cele\cyp-25A1, Cele\cyp-13A1, Cele\cyp-23A1, Cele\cyp-25A3, Cele\cyp-13A5, Cele\cyp-25A4" "Xtro\LOC100494419, Xtro\tbxas1, Xtro\cyp3a5, Xtro\cyp3a4" "Mmus\Cyp3a57, Mmus\Cyp3a59, Mmus\Cyp3a25, Mmus\Cyp3a41b, Mmus\Cyp3a11, Mmus\Cyp3a44, Mmus\Cyp7a1, Mmus\Cyp3a41a, Mmus\Cyp3a16, Mmus\Tbxas1, Mmus\Cyp3a13" "Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A7, Hsap\CYP7A1, Hsap\CYP3A4, Hsap\CYP3A43, Hsap\CYP3A5, Hsap\TBXAS1" viable FBgn0020823 l(3)98Dd lethal (3) 98Dd http://flybase.org/reports/FBgn0020823 - gene - - - "M33, l(3)M3-3, l(3)98D-Ed, l(3)98Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261341 verm vermiform http://flybase.org/reports/FBgn0261341 protein_coding_gene chitin deacetylase activity ; GO:0004099 | inferred from mutant phenotype chitin binding ; GO:0008061 | inferred from mutant phenotype "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR002509, InterPro:IPR011330 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype dorsal trunk growth, open tracheal system ; GO:0035001 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG8756, verm, Verm, hlm, N63, LCBP1, l(3)76BDx, DmCDA2" "IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002557:Chitin binding domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel" CG8756 11-Aug-17 DroID_v2017_08 - - "Cele\F48E3.8, Cele\lgx-1" - - - FBgn0026356 Su(SuRaf1)11 Su(SuRaf1)11 http://flybase.org/reports/FBgn0026356 - gene - - - "Su[Su(Raf)1]11, Su(SuRaf1)11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053218 CR33218 - http://flybase.org/reports/FBgn0053218 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT9762, CG2854, CG33218, CR33218" - CR33218 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022356 Taf105 TBP-associated factor 105kD http://flybase.org/reports/FBgn0022356 - gene TBP-class protein binding ; GO:0017025 | inferred from physical interaction with Tbp transcription from RNA polymerase III promoter ; GO:0006383 | inferred from physical interaction with Tbp transcription factor TFIIIB complex ; GO:0000126 | inferred from direct assay "TAF, dTAF[[III]]105, Taf105" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051923 CG31923 - http://flybase.org/reports/FBgn0051923 protein_coding_gene - - - "BcDNA:RH63623, CG31923" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005441 l(1)v135 lethal (1) v135 http://flybase.org/reports/FBgn0005441 - gene - - - "l(1)135, l(1)v135" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002414 l(3)DTS1 lethal (3) DTS1 http://flybase.org/reports/FBgn0002414 - gene - - - "DTS-1, l(3)DTS1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,visible" FBgn0024238 Fim Fimbrin http://flybase.org/reports/FBgn0024238 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000462453 actin binding ; GO:0003779 | inferred from sequence or structural similarity actin filament bundle assembly ; GO:0051017 | inferred from biological aspect of ancestor with PANTHER:PTN000462453 actin crosslink formation ; GO:0051764 | inferred from biological aspect of ancestor with PANTHER:PTN000462453 female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype actin filament network formation ; GO:0051639 | inferred from biological aspect of ancestor with PANTHER:PTN000462453 actin filament ; GO:0005884 | inferred from biological aspect of ancestor with PANTHER:PTN000462453 contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay actin filament bundle ; GO:0032432 | inferred from biological aspect of ancestor with PANTHER:PTN000462453 "CG8649, Fim, FIM, fim" "IPR018247:EF-Hand 1, calcium-binding site, IPR001589:Actinin-type actin-binding domain, conserved site, IPR001715:Calponin homology domain, IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG8649 11-Aug-17 DroID_v2017_08 "Drer\LOC100537803, Drer\pls3, Drer\pls1, Drer\lcp1" Scer\SAC6 "Cele\Y73B3B.1, Cele\plst-1" "Xtro\lcp1, Xtro\pls3, Xtro\pls1" "Mmus\Pls3, Mmus\Lcp1, Mmus\Pls1" "Hsap\PLS1, Hsap\LCP1, Hsap\PLS3" "viable,fertile,meiotic cell cycle defective,dominant,partially lethal - majority die,some die during pupal stage" DRSC20243 I -0.266587214 -1.690036211 -0.615357685 -0.155843439 -0.883148216 -0.136374613 FBgn0266404 CR45044 - http://flybase.org/reports/FBgn0266404 non_protein_coding_gene - - - CR45044 - CR45044 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023074 l(1)19Eg lethal (1) 19Eg http://flybase.org/reports/FBgn0023074 - gene - - - "B2/32.16, l(1)19Eg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039519 Cyp6a18 Cyp6a18 http://flybase.org/reports/FBgn0039519 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "6a18, CG13977, Cyp6a18, CYP6a18, cyp6a18" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG13977 11-Aug-17 DroID_v2017_08 "Drer\cyp4t8, Drer\cyp3a65, Drer\cyp3c4, Drer\tbxas1, Drer\cyp3c1, Drer\cyp3c2, Drer\cyp4v8, Drer\cyp3c3, Drer\cyp4f3, Drer\cyp4v7" Scer\ERG11 "Cele\cyp-25A2, Cele\cyp-13A1, Cele\cyp-13B1, Cele\cyp-13A11, Cele\cyp-43A1, Cele\cyp-37B1, Cele\cyp-25A1, Cele\cyp-29A4, Cele\cyp-32A1, Cele\cyp-13A8, Cele\cyp-29A2, Cele\cyp-42A1, Cele\cyp-13A10, Cele\cyp-13A4, Cele\cyp-29A3, Cele\cyp-13A5, Cele\cyp-13A12, Cele\cyp-13A3, Cele\cyp-13A6, Cele\cyp-44A1, Cele\cyp-13A2, Cele\cyp-13A7, Cele\cyp-32B1, Cele\cyp-25A6, Cele\cyp-13B2, Cele\cyp-25A3, Cele\cyp-31A2, Cele\cyp-31A3, Cele\cyp-25A4" "Xtro\LOC100494419, Xtro\cyp3a5, Xtro\tbxas1, Xtro\cyp3a4" "Mmus\Cyp4f14, Mmus\Cyp3a25, Mmus\Cyp3a44, Mmus\Cyp4f15, Mmus\Cyp3a11, Mmus\Cyp3a41a, Mmus\Cyp4f13, Mmus\Cyp4b1, Mmus\Cyp4a31, Mmus\Cyp3a41b, Mmus\Cyp4f37, Mmus\Cyp4f16, Mmus\Tbxas1, Mmus\Cyp4a10, Mmus\Cyp4a14, Mmus\Cyp4a12b, Mmus\Cyp3a13, Mmus\Cyp3a16, Mmus\Cyp4v3, Mmus\Cyp4f18, Mmus\Cyp4a32, Mmus\Cyp4a12a, Mmus\Cyp3a59, Mmus\Cyp4f39, Mmus\Cyp3a57" "Hsap\CYP4F12, Hsap\CYP4F2, Hsap\TBXAS1, Hsap\CYP4F8, Hsap\CYP4B1, Hsap\CYP4X1, Hsap\CYP3A7, Hsap\CYP4F22, Hsap\CYP4Z1, Hsap\CYP3A5, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4A11, Hsap\CYP4A22, Hsap\CYP4V2, Hsap\CYP4F11, Hsap\CYP3A43, Hsap\CYP4F3, Hsap\CYP3A4" viable FBgn0013730 ry::Cvic\Xdh Xdh http://flybase.org/reports/FBgn0013730 - engineered_fusion_gene - - - "ry::Cvic\ry, ry::Cvic\Xdh" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065870 l(2)SH0259 lethal (2) SH0259 http://flybase.org/reports/FBgn0065870 gene - - - "l(2)SH0259, l(2)SH2 0259" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267924 CR46205 - http://flybase.org/reports/FBgn0267924 non_protein_coding_gene - - - "CR46205, lincRNA.S592" - CR46205 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262844 CG43208 - http://flybase.org/reports/FBgn0262844 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43208, MB6.chr3R.pasa.10072" - CG43208 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022217 l(2)k03609 lethal (2) k03609 http://flybase.net/reports/FBgn0022217.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0265660 CR44467 - http://flybase.org/reports/FBgn0265660 non_protein_coding_gene - - - "lincRNA.328, CR44467" - CR44467 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052271 CG32271 - http://flybase.org/reports/FBgn0052271 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP176, CG11532, CG32271" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG32271 11-Aug-17 DroID_v2017_08 - - "Cele\try-1, Cele\try-5, Cele\svh-1" - "Mmus\Klk6, Mmus\Prss55" Hsap\KLK6 viable DRSC08198 E 1.437365142 0.619467499 2.21316184 0.176839796 -0.872755352 -0.417877818 FBgn0010313 corto corto http://flybase.org/reports/FBgn0010313 "FBgn0010917, FBgn0011464, FBgn0011465, FBgn0016125, FBgn0066000" protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P39769 inferred from physical interaction with UniProtKB:P42124 inferred from physical interaction with UniProtKB:Q24338 inferred from physical interaction with UniProtKB:Q9VHA0 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P41046 identical protein binding ; GO:0042802 | inferred from physical interaction with UniProtKB:P41046 "regulation of gene expression ; GO:0010468 | inferred from direct assay male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred by curator from GO:0035098 inferred by curator from GO:0035102 epithelium development ; GO:0060429 | inferred from genetic interaction with Abd-B imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype" polytene chromosome ; GO:0005700 | inferred from direct assay ESC/E(Z) complex ; GO:0035098 | inferred from physical interaction with UniProtKB:P42124 inferred from physical interaction with UniProtKB:Q24338 nucleus ; GO:0005634 | inferred from direct assay PRC1 complex ; GO:0035102 | inferred from physical interaction with UniProtKB:P39769 inferred from physical interaction with UniProtKB:Q9VHA0 centrosome ; GO:0005813 | inferred from direct assay "CG2530, Ccf, CP-1, ccf, l(3)07128, l(3)neo31, 7128, l(3)neo32, anon-WO02059370.59, corto, Corto" IPR015943:WD40/YVTN repeat-like-containing domain CG2530 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | >=4hr , larval stage && pupal stage && adult stage , embryonic stage -- adult stage " "song defective,viable,female sterile,lethal,recessive,visible,dominant,partially lethal - majority die,wild-type,somatic clone,polyphasic,mitotic cell cycle defective,heat sensitive,homeotic,size defective" "macrochaeta,chorion,wing vein,ectopic,crystal cell,plasmatocyte,germline cell,male,somatic clone,imaginal disc,embryonic/larval salivary gland,embryonic/larval lymph gland,embryonic/larval brain,ring gland,gastric caecum,melanotic mass,external sensory organ,adult abdomen & macrochaeta,posterior crossvein,adult head,eye,prothoracic tarsal segment 2,sex comb,adult thorax & macrochaeta,trichogen cell,supernumerary,humerus,humeral bristle,wing,arista,haltere,genitalia,scutellar bristle,leg,scutellum,male genitalia" DRSC22988 K -0.009539051 0.451617063 0.940864345 0.644641466 2.313807191 -0.208559288 FBgn0010937 l(3)09904c lethal (3) 09904c http://flybase.org/reports/FBgn0010937 - gene - - - "l(3)09904, l(3)09904c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "ovariole,germline clone,egg" FBgn0003414 Streak Streak http://flybase.org/reports/FBgn0003414 - gene - - - "Streak, Sk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,body color defective" "wing,scutellum" FBgn0003212 rc red cells http://flybase.org/reports/FBgn0003212 - gene - - - "rbc, rc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037107 CG7166 - http://flybase.org/reports/FBgn0037107 protein_coding_gene - - - "CT22143, CG7166" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR013106:Immunoglobulin V-set domain" CG7166 11-Aug-17 DroID_v2017_08 "Drer\si:zfos-1011f11.1, Drer\jam3a, Drer\vsig8b, Drer\si:ch73-22o12.1, Drer\jam3b, Drer\ntm, Drer\zgc:110372, Drer\cxcr3.1, Drer\esamb, Drer\mxra8b, Drer\vsig8a, Drer\f11r.1, Drer\cd22, Drer\jam2a, Drer\pvrl3a, Drer\zgc:153073, Drer\si:dkey-65b12.12, Drer\negr1, Drer\igsf11, Drer\jam2b, Drer\pvrl2l, Drer\opcml, Drer\f11r.2, Drer\gpa33, Drer\esama, Drer\LOC101885775, Drer\cxadr, Drer\mxra8a, Drer\si:dkey-250k15.10" - "Cele\rig-5, Cele\wrk-1" "Xtro\siglec10, Xtro\ntm, Xtro\lsamp, Xtro\negr1, Xtro\LOC100145501, Xtro\pvrl1" "Mmus\Vsir, Mmus\Iglon5, Mmus\Cilp, Mmus\Gpa33, Mmus\Cxadr, Mmus\Cd33, Mmus\Igsf11, Mmus\Ntm, Mmus\Opcml, Mmus\Vsig2, Mmus\Siglecg, Mmus\Vsig8, Mmus\Gm1123, Mmus\Jam3, Mmus\Siglece, Mmus\Igsf5, Mmus\Clmp, Mmus\Mag, Mmus\Mxra8, Mmus\Siglecf, Mmus\Lsamp, Mmus\F11r, Mmus\Negr1, Mmus\Fgfrl1, Mmus\Jam2, Mmus\Esam, Mmus\Hepacam2, Mmus\Vsig1" "Hsap\CXADR, Hsap\SIGLEC10, Hsap\CILP, Hsap\IGSF5, Hsap\JAM2, Hsap\MXRA8, Hsap\VSIG1, Hsap\NTM, Hsap\JAM3, Hsap\IGLON5, Hsap\SIGLEC6, Hsap\SIGLEC8, Hsap\SIGLEC14, Hsap\GPA33, Hsap\OPCML, Hsap\SIGLEC11, Hsap\VSIG2, Hsap\SIGLEC5, Hsap\C1orf204, Hsap\LSAMP, Hsap\SIGLEC12, Hsap\NECTIN1, Hsap\NEGR1, Hsap\IGSF11, Hsap\ESAM, Hsap\VSIG8, Hsap\SIGLEC9, Hsap\SIGLEC7, Hsap\CLMP, Hsap\F11R, Hsap\MAG, Hsap\C10orf54" "viable,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039731 Sas-6 Spindle assembly abnormal 6 http://flybase.org/reports/FBgn0039731 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sas-4 centriole replication ; GO:0007099 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from direct assay centrosome duplication ; GO:0051298 | inferred from sequence or structural similarity with UniProtKB:Q6UVJ0 centriole-centriole cohesion ; GO:0010457 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay centriole ; GO:0005814 | colocalizes_with inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay centrosome ; GO:0005813 | inferred from sequence or structural similarity with UniProtKB:Q6UVJ0 "Sas-6, CG15524, DSAS-6, DSas-6, SAS-6, dsas-6, Dsas6, Sas6, SAS6, DSas6, sas-6" "IPR032396:Spindle assembly abnormal protein 6, N-terminal" CG15524 11-Aug-17 DroID_v2017_08 Drer\sass6 - - "Xtro\sass6, Xtro\sass6.2" Mmus\Sass6 Hsap\SASS6 "viable,fertile,partially lethal - majority die,some die during pupal stage,uncoordinated" "embryonic/larval brain,embryo,centriole,centrosome,centriole | ectopicmat.‘±Tub67C.THsimVP16,centriole | ectopic,spermatid,spermatocyte" FBgn0039596 CG10000 - http://flybase.org/reports/FBgn0039596 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern oligosaccharide biosynthetic process ; GO:0009312 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 - "CG10000, dppGalNAcT10" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG10000 11-Aug-17 DroID_v2017_08 "Drer\galnt18a, Drer\galnt2, Drer\galnt18b, Drer\galnt10, Drer\galnt8b, Drer\galnt8a.1, Drer\galnt11, Drer\galnt9, Drer\galnt16, Drer\LOC568645, Drer\galnt14, Drer\LOC100535692, Drer\wbscr17" - "Cele\gly-11, Cele\gly-8" "Xtro\galnt15, Xtro\galnt16, Xtro\galnt2, Xtro\galnt9, Xtro\galnt14, Xtro\wbscr17" "Mmus\Galntl5, Mmus\Galnt9, Mmus\Galnt15, Mmus\Galnt16, Mmus\Galnt18, Mmus\Wbscr17, Mmus\Galnt11, Mmus\Galnt2, Mmus\Galnt14" "Hsap\GALNT16, Hsap\GALNT8, Hsap\GALNTL5, Hsap\GALNT15, Hsap\GALNT9, Hsap\GALNT14, Hsap\GALNT2, Hsap\WBSCR17, Hsap\GALNT11, Hsap\GALNT18" "viable,body color defective" mesothoracic tergum FBgn0029771 CG12730 - http://flybase.org/reports/FBgn0029771 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001103553 "BcDNA:RE01432, CG12730" IPR008253:Marvel domain CG12730 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-66d1.7, Drer\cmtm6, Drer\LOC100536607, Drer\zgc:158773, Drer\cmtm3, Drer\cmtm7, Drer\LOC101882206, Drer\zgc:136605, Drer\LOC101882154, Drer\pllp, Drer\myadml2, Drer\cmtm8b, Drer\plp2, Drer\cmtm8a, Drer\marveld1, Drer\mal2, Drer\cmtm4" - "Cele\K09G1.1, Cele\F47B3.3, Cele\drr-1, Cele\F28H1.4" "Xtro\plp2, Xtro\cmtm7, Xtro\cmtm6, Xtro\mal2, Xtro\myadml2, Xtro\pllp, Xtro\cmtm3, Xtro\myadm, Xtro\mal" "Mmus\Cmtm2a, Mmus\Cmtm6, Mmus\Cmtm7, Mmus\Cklf, Mmus\Plp2, Mmus\Marveld1, Mmus\Mal, Mmus\Cmtm2b, Mmus\Cmtm3, Mmus\Mal2, Mmus\Myadml2, Mmus\Cmtm4, Mmus\Cmtm8, Mmus\Pllp, Mmus\Myadm, Mmus\Cmtm5, Mmus\Cmtm1" "Hsap\PLP2, Hsap\CKLF, Hsap\CMTM3, Hsap\CMTM6, Hsap\MAL, Hsap\MARVELD1, Hsap\MYADML2, Hsap\CMTM7, Hsap\CMTM1, Hsap\CMTM8, Hsap\MYADM, Hsap\CMTM4, Hsap\PLLP, Hsap\CKLF-CMTM1, Hsap\CMTM2, Hsap\CMTM5" FBgn0027329 CCT6 Chaperonin containing TCP1 subunit 6 http://flybase.org/reports/FBgn0027329 "FBgn0026695, FBgn0027326, FBgn0030681" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012722 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000143755 lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "l(1)G0027, l(1)G0057, CG8231, Tcp-1zeta, Tcp-1-zeta, l(1)G0022, Rcd3, TCP-1-zeta, L(1)g0022, TCP-1zeta, CCT6, Q9VXQ5_DROME, TCP1zeta, TCPzeta, TCP1-zeta" "IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012722:T-complex protein 1, zeta subunit, IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG8231 11-Aug-17 DroID_v2017_08 "Drer\bbs12, Drer\cct6a" Scer\CCT6 Cele\cct-6 Xtro\cct6a "Mmus\Cct6b, Mmus\Cct6a" "Hsap\CCT6B, Hsap\CCT6A" "lethal,some die during immature adult stage,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" DRSC20095 I 1.834662738 -0.061023917 0.965202838 -0.283467013 0.137629995 -0.33206413 FBgn0028621 l(2)06655 lethal (2) 06655 http://flybase.org/reports/FBgn0028621 gene - - - l(2)06655 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085575 CG41249 - http://flybase.org/reports/FBgn0085575 protein_coding_gene - - - CG41249 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002563 Lsp1beta Larval serum protein 1 beta http://flybase.org/reports/FBgn0002563 - protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype larval serum protein complex ; GO:0005616 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Lsp1, Lsp1b, CG4178, DmeLSP1b, Lsp-1b, LSP-1beta, Lsp-1beta, LSP 1, LSP1beta, Lsp1-beta, LSP-1, LSP-1 beta, Lsp1beta, LSP1, Lsp1[beta]" "IPR000896:Hemocyanin/hexamerin middle domain, IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR008922:Uncharacterised domain, di-copper centre, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set" CG4178 11-Aug-17 DroID_v2017_08 - - "Cele\C49A9.2, Cele\C49A9.3, Cele\F58F9.4" - - - " larval stage | second instar -- larval stage | third instar , larval stage | third instar " embryonic/larval fat body

"electrophoretic variant,viable,visible" "egg,chaeta" FBgn0000913 fs(1)MY18 female sterile (1) MY18 http://flybase.org/reports/FBgn0000913 - gene - - - "fs(1)MY-18, fs(1)MY18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" "pole cell,cephalic furrow,labral segment,embryonic/larval midgut" FBgn0014063 Su(tor)3-168 Su(tor)3-168 http://flybase.org/reports/FBgn0014063 - gene - - - Su(tor)3-168 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267077 CR45521 - http://flybase.org/reports/FBgn0267077 non_protein_coding_gene - - - CR45521 - CR45521 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011119 l(1)Q80 lethal (1) Q80 http://flybase.org/reports/FBgn0011119 FBgn0010210 gene - - - l(1)Q80 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038237 Pde6 Phosphodiesterase 6 http://flybase.org/reports/FBgn0038237 protein_coding_gene "3',5'-cyclic-GMP phosphodiesterase activity ; GO:0047555 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VLJ0" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002073 cGMP metabolic process ; GO:0046068 | inferred from direct assay negative regulation of nucleobase-containing compound transport ; GO:0032240 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "PDE6, CG8279, Pde6, DmPDE5/6, DmPDE6" "IPR002073:3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR003018:GAF domain, IPR003607:HD/PDEase domain, IPR029016:GAF domain-like, IPR023088:3'5'-cyclic nucleotide phosphodiesterase, IPR023174:3'5'-cyclic nucleotide phosphodiesterase, conserved site" CG8279 11-Aug-17 DroID_v2017_08 "Drer\crtc1b, Drer\pde6c, Drer\pde4ba, Drer\pde9al, Drer\pde4ca, Drer\pde6a, Drer\si:dkey-219c10.4, Drer\pde2a, Drer\pde9a, Drer\pde4d, Drer\pde6b, Drer\pde4a, Drer\pde4bb, Drer\pde11a, Drer\pde7a, Drer\LOC571737, Drer\pde5ab, Drer\pde11al, Drer\pde5aa, Drer\pde10a" Scer\PDE2 "Cele\pde-5, Cele\pde-2" "Xtro\pde4c, Xtro\pde5a, Xtro\pde7a, Xtro\pde7b, Xtro\pde6b, Xtro\pde11a, Xtro\pde6c, Xtro\LOC100493061, Xtro\pde6a, Xtro\pde2a, Xtro\pde9a, Xtro\pde4a, Xtro\pde4b, Xtro\pde4d, Xtro\pde10a" "Mmus\Pde6a, Mmus\Pde4b, Mmus\Pde11a, Mmus\Pde4a, Mmus\Pde2a, Mmus\Pde9a, Mmus\Pde10a, Mmus\Pde7b, Mmus\Pde6b, Mmus\Pde6c, Mmus\Pde4c, Mmus\Pde5a, Mmus\Pde4d, Mmus\Pde7a" "Hsap\PDE7A, Hsap\PDE10A, Hsap\PDE4A, Hsap\PDE4C, Hsap\PDE2A, Hsap\PDE4B, Hsap\PDE6C, Hsap\PDE6A, Hsap\PDE4D, Hsap\PDE7B, Hsap\PDE11A, Hsap\PDE6B, Hsap\PDE5A, Hsap\PDE9A" "viable,fertile" FBgn0061014 l(3)S026020a lethal (3) S026020a http://flybase.org/reports/FBgn0061014 gene - - - "0260/20, l(3)S026020a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266094 CR44831 - http://flybase.org/reports/FBgn0266094 non_protein_coding_gene - - - CR44831 - CR44831 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031914 CG5973 - http://flybase.org/reports/FBgn0031914 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 molecular_function ; GO:0003674 | no biological data available transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 sleep ; GO:0030431 | inferred from expression pattern intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 cellular_component ; GO:0005575 | no biological data available CG5973 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG5973 11-Aug-17 DroID_v2017_08 "Drer\rlbp1a, Drer\clvs2, Drer\sec14l7, Drer\ttpal, Drer\sec14l8, Drer\ttpa" "Scer\SEC14, Scer\YKL091C, Scer\SFH5" - "Xtro\ttpa, Xtro\rlbp1, Xtro\sec14l1, Xtro\ttpal, Xtro\sec14l5, Xtro\clvs2, Xtro\sec14l3, Xtro\clvs1, Xtro\mospd2" "Mmus\Sec14l4, Mmus\Clvs2, Mmus\Clvs1, Mmus\Ttpal, Mmus\Sec14l3, Mmus\Sec14l2, Mmus\Sec14l5, Mmus\Ttpa, Mmus\Rlbp1, Mmus\Sec14l1" "Hsap\SEC14L4, Hsap\SEC14L5, Hsap\TTPA, Hsap\CLVS2, Hsap\RLBP1, Hsap\SEC14L6, Hsap\TTPAL, Hsap\SEC14L2, Hsap\CLVS1, Hsap\SEC14L3, Hsap\SEC14L1" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0034784 CG9826 - http://flybase.org/reports/FBgn0034784 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 CG9826 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG9826 11-Aug-17 DroID_v2017_08 "Drer\slc17a5, Drer\ppt1, Drer\slc17a9a, Drer\slc17a6a, Drer\si:ch1073-513e17.1, Drer\slc17a7a, Drer\slc17a8, Drer\slc17a6b" "Scer\THI73, Scer\TNA1, Scer\DAL5, Scer\YIL166C" "Cele\T19D12.10, Cele\D1046.4, Cele\T27D12.1, Cele\K11G9.5, Cele\slc-17.2, Cele\C01B4.7, Cele\T01H3.3, Cele\R10D12.1, Cele\Y4C6B.4, Cele\F56A4.12, Cele\F56A4.10, Cele\C18H9.5, Cele\F41C3.2, Cele\C01B4.8, Cele\Y19D10A.11, Cele\T19D12.9, Cele\M162.5, Cele\T22F3.8, Cele\H11E01.2, Cele\F10C2.7, Cele\M117.1, Cele\slc-17.3, Cele\T22F3.11, Cele\slc-17.1, Cele\F44E7.7, Cele\eat-4, Cele\slc-17.8, Cele\vglu-2, Cele\Y19D10A.8, Cele\C35A5.3, Cele\T22F3.10, Cele\Y4C6B.3, Cele\K08C7.1, Cele\vglu-3, Cele\F11A5.9, Cele\Y15E3A.4, Cele\F59A1.13, Cele\slc-17.5, Cele\slc-17.9, Cele\W04C9.6, Cele\T22F3.7, Cele\C39E9.7, Cele\Y19D10A.5, Cele\slc-17.4, Cele\C18D1.2, Cele\T02B11.6, Cele\cima-1, Cele\Y51B9A.6, Cele\Y19D10A.4, Cele\T28H11.8" Xtro\slc17a7 "Mmus\Slc17a8, Mmus\Slc17a6, Mmus\Slc17a2, Mmus\Slc17a3, Mmus\Slc17a5, Mmus\Slc17a4, Mmus\Slc17a1, Mmus\Slc17a7" "Hsap\SLC17A3, Hsap\SLC17A4, Hsap\SLC17A6, Hsap\SLC17A5, Hsap\SLC17A7, Hsap\SLC17A2, Hsap\SLC17A1, Hsap\SLC17A8" "viable,visible" trichogen cell FBgn0039017 CG6985 - http://flybase.org/reports/FBgn0039017 protein_coding_gene - - - CG6985 IPR018838:Domain of unknown function DUF2439 CG6985 11-Aug-17 DroID_v2017_08 "Drer\rad54l, Drer\rad54b" "Scer\RAD54, Scer\RDH54" - "Xtro\rad54l, Xtro\rad54b" "Mmus\Rad54l, Mmus\Rad54b" "Hsap\RAD54L, Hsap\RAD54B" FBgn0001372 l(1)2Ae lethal (1) 2Ae http://flybase.org/reports/FBgn0001372 - gene - - - "l(1)BA12, l(1)2Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "eye,wing,macrochaeta,maxillary palp bristle" FBgn0265072 CR44183 - http://flybase.org/reports/FBgn0265072 non_protein_coding_gene - - - "CR44183, lincRNA.125" - CR44183 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020638 Lcp65Ag1 Lcp65Ag1 http://flybase.org/reports/FBgn0020638 FBgn0002539 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence or structural similarity structural constituent of chitin-based larval cuticle ; GO:0008010 | non-traceable author statement structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model larval chitin-based cuticle development ; GO:0008363 | non-traceable author statement chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular region ; GO:0005576 | non-traceable author statement extracellular matrix ; GO:0031012 | inferred from sequence model "Lcp-g1, LCP8, L[[3]]CP8, Lcp8, DCP8-alpha, CG10530, Lcp65Ag1" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG10530 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\math-34, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " embryonic stage , larval stage , pupal stage | 7-13 hr " "electrophoretic variant,slow" FBgn0043031 l(2)42Cd lethal (2) 42Cd http://flybase.org/reports/FBgn0043031 gene - - - l(2)42Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037644 CG11964 - http://flybase.org/reports/FBgn0037644 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available spliceosomal complex ; GO:0005681 | inferred from biological aspect of ancestor with PANTHER:PTN000384656 CG11964 "IPR013180:Beta-catenin-like protein 1, N-terminal, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG11964 11-Aug-17 DroID_v2017_08 Drer\ctnnbl1 - Cele\M01E11.2 Xtro\ctnnbl1 Mmus\Ctnnbl1 Hsap\CTNNBL1 viable FBgn0065783 l(2)SH0440 lethal (2) SH0440 http://flybase.org/reports/FBgn0065783 gene - - - l(2)SH0440 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069208 l(1)XPG-L lethal (1) XPG-L http://flybase.org/reports/FBgn0069208 gene - - - l(1)XPG-L - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260024 rey-del-mundo rey del mundo http://flybase.org/reports/FBgn0260024 gene - - - rey-del-mundo - - 11-Aug-17 DroID_v2017_08 - - - - - - chorion | germline clone FBgn0000153 b black http://flybase.org/reports/FBgn0000153 "FBgn0005622, FBgn0020605" protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 aspartate 1-decarboxylase activity ; GO:0004068 | inferred from sequence or structural similarity aspartate 1-decarboxylase activity ; GO:0004068 | inferred from mutant phenotype carboxylic acid metabolic process ; GO:0019752 | inferred from electronic annotation with InterPro:IPR002129 visual behavior ; GO:0007632 | inferred from mutant phenotype developmental pigmentation ; GO:0048066 | traceable author statement beta-alanine biosynthetic process ; GO:0019483 | traceable author statement uracil catabolic process ; GO:0006212 | traceable author statement - "black, b, anon-34Db, Gad2, BG:DS00941.5, DGad2, cDNA 1, GAD[[2]], DmGad2, CG7811, B, ADC" "IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG7811 11-Aug-17 DroID_v2017_08 "Drer\csad, Drer\gad1a, Drer\gad1b, Drer\gad2, Drer\zgc:163121" - Cele\unc-25 "Xtro\csad, Xtro\gadl1, Xtro\gad2, Xtro\gad1.1, Xtro\gad1.2" "Mmus\Gadl1, Mmus\Gad2, Mmus\Gad1, Mmus\Csad" "Hsap\CSAD, Hsap\GAD1, Hsap\GADL1, Hsap\GAD2" adult stage " dorsal medial muscle

, lamina neuropil

, mesothoracic extracoxal depressor muscle 66

" "body color defective,viable,lethal,visual behavior defective,visible,recessive,dominant" "adult cuticle,wing vein,tarsal segment,trident,puparium" FBgn0044386 Scim8 Sensitized chromosome inheritance modifier 8 http://flybase.org/reports/FBgn0044386 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0005212 l(3)ET2 lethal Elaine Tasaka 2 http://flybase.org/reports/FBgn0005212 - gene - - - l(3)ET2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cold sensitive" FBgn0266992 CR45443 - http://flybase.org/reports/FBgn0266992 non_protein_coding_gene - - - "CR45443, CR45671" - CR45443 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051643 CG31643 - http://flybase.org/reports/FBgn0051643 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR010622 molecular_function ; GO:0003674 | no biological data available protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:24676 cellular_component ; GO:0005575 | no biological data available "CG31643PA, BcDNA:LD32258, CG31643" "IPR010622:FAST kinase leucine-rich, IPR013579:FAST kinase-like protein, subdomain 2, IPR013584:RAP domain" CG31643 11-Aug-17 DroID_v2017_08 "Drer\fastkd2, Drer\fastk, Drer\fastkd1, Drer\fastkd3" - - "Xtro\fastkd1, Xtro\fastkd3" "Mmus\Fastk, Mmus\Fastkd3, Mmus\Fastkd2, Mmus\Fastkd1" "Hsap\FASTK, Hsap\FASTKD2, Hsap\FASTKD1, Hsap\FASTKD3, Hsap\TBRG4" FBgn0001733 l(1)HM1 lethal (1) HM1 http://flybase.org/reports/FBgn0001733 - gene - - - l(1)HM1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female sterile" FBgn0037988 CG14740 - http://flybase.org/reports/FBgn0037988 protein_coding_gene citrate (Si)-synthase activity ; GO:0004108 | inferred from sequence or structural similarity with UniProtKB:O75390 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:O75390 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:O75390 "anon-WO0140519.178, CG14740, CS" "IPR002020:Citrate synthase, IPR016142:Citrate synthase-like, large alpha subdomain, IPR019810:Citrate synthase active site, IPR016143:Citrate synthase-like, small alpha subdomain" CG14740 11-Aug-17 DroID_v2017_08 Drer\cs "Scer\CIT2, Scer\CIT1, Scer\CIT3" Cele\cts-1 Xtro\cs "Mmus\Cs, Mmus\Csl" Hsap\CS viable FBgn0031523 CG15408 - http://flybase.org/reports/FBgn0031523 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG15408 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG15408 11-Aug-17 DroID_v2017_08 "Drer\slc2a10, Drer\slc2a13b, Drer\slc2a12, Drer\slc2a6, Drer\slc2a8, Drer\LOC101882338" "Scer\HXT7, Scer\GEX1, Scer\VBA2, Scer\YDL199C, Scer\ENB1, Scer\ITR2, Scer\HXT3, Scer\GAL2, Scer\HXT4, Scer\YFL040W, Scer\VBA1, Scer\MAL31, Scer\MAL11, Scer\HXT15, Scer\HXT1, Scer\AZR1, Scer\MPH3, Scer\SGE1, Scer\HXT8, Scer\VBA3, Scer\HXT10, Scer\HXT16, Scer\ATR1, Scer\HXT13, Scer\HXT11, Scer\HXT17, Scer\VBA5, Scer\SNF3, Scer\HXT9, Scer\HXT14, Scer\VBA4, Scer\HXT6, Scer\YMR279C, Scer\ITR1, Scer\YDR387C, Scer\RGT2, Scer\MPH2, Scer\HXT5, Scer\HXT2, Scer\GEX2, Scer\STL1" Cele\K09C4.5 "Xtro\slc2a12, Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a10" "Mmus\Slc2a6, Mmus\Slc2a13, Mmus\Slc2a12, Mmus\Slc2a8, Mmus\Slc2a10" "Hsap\SLC2A6, Hsap\SLC2A8, Hsap\SLC2A10, Hsap\SLC2A13, Hsap\SLC2A12, Hsap\SLC2A5" viable FBgn0065340 l(2)SH1835 lethal (2) SH1835 http://flybase.org/reports/FBgn0065340 gene - - - "l(2)SH1835, l(2)SH2 1835" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052440 CG32440 - http://flybase.org/reports/FBgn0052440 protein_coding_gene - - - "CG5051, bs36c07.y1, CG32440" - CG32440 11-Aug-17 DroID_v2017_08 - - - - - - DRSC11480 K 0.045629048 -0.627357427 -0.122462445 0.67641815 1.609674388 3.659857788 FBgn0085823 CR41617 - http://flybase.org/reports/FBgn0085823 rRNA_gene - - - CR41617 - CR41617 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260602 2L1685 - http://flybase.org/reports/FBgn0260602 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1685 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0010296 ng4 new glue 4 http://flybase.org/reports/FBgn0010296 - protein_coding_gene - - - "ng-4, ng, EG:96G10.2, CG10789, ng4" - CG10789 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | first instar -- larval stage | second instar , pupal stage " organism

viable FBgn0065255 l(2)SH2111 lethal (2) SH2111 http://flybase.org/reports/FBgn0065255 gene - - - "l(2)SH2111, l(2)SH2 2111" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026089 CG14817 - http://flybase.org/reports/FBgn0026089 - protein_coding_gene - - mitochondrial ribosome ; GO:0005761 | inferred from electronic annotation with InterPro:IPR016576 "EG:63B12.11, CG14817" "IPR016576:Ribosomal protein 63, mitochondrial" CG14817 11-Aug-17 DroID_v2017_08 Drer\mrpl57 - - - Mmus\Mrpl57 Hsap\MRPL57 "viable,visible" trichogen cell FBgn0037671 VhaM8.9 Vacuolar H[+] ATPase M8.9 accessory subunit http://flybase.org/reports/FBgn0037671 protein_coding_gene receptor activity ; GO:0004872 | inferred from electronic annotation with InterPro:IPR012493 frizzled-2 binding ; GO:0005110 | inferred from direct assay frizzled binding ; GO:0005109 | inferred from direct assay "Wnt signaling pathway, planar cell polarity pathway ; GO:0060071 | inferred from genetic interaction with fz presynaptic process involved in chemical synaptic transmission ; GO:0099531 | inferred from mutant phenotype axonal transport ; GO:0098930 | inferred from mutant phenotype establishment of body hair or bristle planar orientation ; GO:0048104 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence or structural similarity with HGNC:18305 establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype protein localization involved in establishment of planar polarity ; GO:0090251 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012493 plasma membrane ; GO:0005886 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay vacuolar proton-transporting V-type ATPase complex ; GO:0016471 | inferred from sequence or structural similarity with HGNC:18305 intracellular ; GO:0005622 | inferred from direct assay "CG8444, VhaPRR, VhaM8.9, dPRR, VhaM8-9, ATP6AP2, vhaM8.9" IPR012493:Renin receptor-like CG8444 11-Aug-17 DroID_v2017_08 Drer\atp6ap2 - "Cele\T14B4.3, Cele\vha-20" Xtro\atp6ap2 Mmus\Atp6ap2 Hsap\ATP6AP2 "lethal,visible,somatic clone,planar polarity defective,viable,partially lethal - majority die,lethal - all die before end of first instar larval stage,some die during first instar larval stage" "wing hair,somatic clone,chaeta,macrochaeta,microchaeta,wing,wing vein,ectopic,wing margin bristle,trichogen cell" FBgn0052249 CG32249 - http://flybase.org/reports/FBgn0052249 protein_coding_gene - - - CG32249 - CG32249 11-Aug-17 DroID_v2017_08 "Drer\zgc:64189, Drer\vcanb, Drer\acanb, Drer\ly75, Drer\si:ch211-156l18.7, Drer\LOC103909969, Drer\pla2r1" - "Cele\F35A5.4, Cele\clec-9, Cele\clec-31, Cele\clec-18, Cele\clec-4, Cele\clec-50, Cele\clec-148, Cele\F47F2.3, Cele\clec-140" "Xtro\acan, Xtro\vcan, Xtro\pla2r1" "Mmus\Pla2r1, Mmus\Ly75, Mmus\Acan, Mmus\Vcan, Mmus\2300003K06Rik, Mmus\Selplg, Mmus\Uckl1" "Hsap\ACAN, Hsap\PLA2R1, Hsap\SELPLG, Hsap\LY75, Hsap\ZNF512B" "viable,fertile" FBgn0027342 fz4 frizzled 4 http://flybase.org/reports/FBgn0027342 "FBgn0029938, FBgn0046616, FBgn0046624" protein_coding_gene "Wnt-activated receptor activity ; GO:0042813 | inferred from electronic annotation with InterPro:IPR026551 Wnt-activated receptor activity ; GO:0042813 | inferred by curator from GO:0017147 transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity with fz Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt4, wntD" Wnt signaling pathway ; GO:0016055 | inferred from electronic annotation with InterPro:IPR026551 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with fz signal transduction ; GO:0007165 | inferred from sequence or structural similarity with fz integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with fz "DFz4, CG4626, anon-WO0170980.11, anon-WO0170980.10, fz4, Fz4, Dfz4, Dm Fz4" "IPR017981:GPCR, family 2-like, IPR000539:Frizzled protein, IPR015526:Frizzled/secreted frizzled-related protein, IPR020067:Frizzled domain, IPR026551:Frizzled-4" CG4626 11-Aug-17 DroID_v2017_08 "Drer\fzd7b, Drer\fzd3a, Drer\fzd2, Drer\fzd5, Drer\fzd9b, Drer\si:cabz01033205.3, Drer\frzb, Drer\fzd3b, Drer\fzd8a, Drer\szl, Drer\LOC101884738, Drer\fzd4, Drer\fzd10, Drer\sfrp1b, Drer\LOC103908663, Drer\sfrp1a, Drer\fzd8b, Drer\sfrp2, Drer\fzd7a, Drer\fzd9a, Drer\sfrp2l, Drer\corin, Drer\sfrp5, Drer\smo" - "Cele\mig-1, Cele\lin-17" "Xtro\fzd10, Xtro\fzd9, Xtro\mfrp, Xtro\fzd5, Xtro\frzb, Xtro\sfrp2, Xtro\corin, Xtro\frzb2, Xtro\sfrpx, Xtro\fzd3, Xtro\sfrp5, Xtro\fzd8, Xtro\fzd4, Xtro\fzd7, Xtro\szl, Xtro\sfrp1, Xtro\smo, Xtro\col18a1, Xtro\fzd6, Xtro\fzd2" "Mmus\Fzd5, Mmus\Sfrp2, Mmus\Sfrp5, Mmus\Frzb, Mmus\Sfrp4, Mmus\Fzd1, Mmus\Fzd10, Mmus\Fzd2, Mmus\Fzd3, Mmus\Sfrp1, Mmus\Fzd7, Mmus\Fzd4, Mmus\Smo, Mmus\Corin, Mmus\Mfrp, Mmus\Fzd8, Mmus\Fzd6, Mmus\Fzd9" "Hsap\FRZB, Hsap\SFRP2, Hsap\FZD4, Hsap\MFRP, Hsap\SFRP1, Hsap\FZD8, Hsap\SFRP5, Hsap\FZD7, Hsap\FZD9, Hsap\FZD3, Hsap\FZD6, Hsap\SMO, Hsap\CORIN, Hsap\SFRP4, Hsap\FZD5, Hsap\FZD1, Hsap\FZD2, Hsap\FZD10" "fertile,viable" FBgn0033365 CG8170 - http://flybase.org/reports/FBgn0033365 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP54, CG8170" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG8170 11-Aug-17 DroID_v2017_08 "Drer\ela3l, Drer\ctrb1, Drer\zgc:92041, Drer\si:dkey-57c15.4, Drer\zgc:55888, Drer\si:dkey-238d18.3, Drer\ela2l, Drer\zmp:0000001114, Drer\zgc:112285, Drer\zgc:112302, Drer\tmprss9, Drer\zgc:154142, Drer\zgc:92511, Drer\zgc:92745, Drer\ela2, Drer\zgc:112368, Drer\ctrl, Drer\LOC562139, Drer\zgc:112160, Drer\st14a, Drer\zgc:171592" - "Cele\try-1, Cele\svh-1" "Xtro\cela3a, Xtro\ctrb2, Xtro\cela2a, Xtro\LOC100135144, Xtro\ctrb1" "Mmus\Gzma, Mmus\Cela3a, Mmus\Cela3b, Mmus\Ctrb1, Mmus\Gzmm, Mmus\Ctrl, Mmus\Tmprss13, Mmus\St14, Mmus\Prss22, Mmus\Cela2a, Mmus\Ctrc, Mmus\Cela1" "Hsap\GZMM, Hsap\CTRB1, Hsap\CTRC, Hsap\PRSS22, Hsap\CTRB2, Hsap\TMPRSS13, Hsap\ST14, Hsap\CTRL, Hsap\CELA2B, Hsap\GZMA, Hsap\CELA3A, Hsap\CELA3B, Hsap\CELA1, Hsap\CELA2A" FBgn0051450 mRpS18A mitochondrial ribosomal protein S18A http://flybase.org/reports/FBgn0051450 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82919 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9NVS2 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:P82919 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9NVS2 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement cytosolic small ribosomal subunit ; GO:0022627 | inferred from biological aspect of ancestor with PANTHER:PTN000336666 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82919 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9NVS2 "mRpS18c, CG11744, MRP-S18-(3), CG31450, BcDNA:SD13983, mRpS18A" IPR001648:Ribosomal protein S18 CG31450 11-Aug-17 DroID_v2017_08 "Drer\mrps18a, Drer\mrps18c" Scer\RSM18 "Cele\mrps-18A, Cele\T14B4.2" Xtro\mrps18c "Mmus\Mrps18c, Mmus\Mrps18a" "Hsap\MRPS18A, Hsap\MRPS18C" "viable,visible" trichogen cell FBgn0000415 dal daughterless-like http://flybase.org/reports/FBgn0000415 - gene - embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement - dal - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive,mitotic cell cycle defective,paternal effect" nucleus | embryonic stage 4 FBgn0030693 CG8974 - http://flybase.org/reports/FBgn0030693 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-like protein conjugating enzyme binding ; GO:0044390 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10068 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:10068 Derlin-1 retrotranslocation complex ; GO:0036513 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 CG8974 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8974 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-247l8.8, Drer\rnf185, Drer\rnf20, Drer\rnf5, Drer\rnf4, Drer\pex10" "Scer\SLX8, Scer\PEX10, Scer\BRE1" "Cele\rnf-5, Cele\Y47G6A.31, Cele\rfp-1" "Xtro\rnf5, Xtro\rnf185" "Mmus\Trim39, Mmus\Rnf40, Mmus\Rnf185, Mmus\Rnf20, Mmus\Pex10, Mmus\Rnf4, Mmus\Rnf5" "Hsap\RNF20, Hsap\TRIM39, Hsap\RNF5, Hsap\RNF4, Hsap\RNF40, Hsap\PEX10, Hsap\RNF185" FBgn0001020 fs(3)A11 female sterile (3) A11 http://flybase.org/reports/FBgn0001020 - gene - - - fs(3)A11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0051869 CG31869 - http://flybase.org/reports/FBgn0051869 protein_coding_gene - - - "CG18499, CG17130, CG31869" IPR001007:VWFC domain CG31869 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-239b22.1, Drer\muc5.2, Drer\muc2.1, Drer\LOC100147904, Drer\LOC100329651, Drer\LOC101887000, Drer\muc5.1, Drer\tecta, Drer\si:ch211-39f2.3, Drer\otog, Drer\scospondin, Drer\si:dkey-65b12.6" - Cele\T01D3.6 - "Mmus\9530053A07Rik, Mmus\Otogl, Mmus\Muc6, Mmus\Muc2, Mmus\Zan, Mmus\Muc5ac, Mmus\Sspo, Mmus\Fcgbp, Mmus\Muc19, Mmus\Tecta, Mmus\Muc5b, Mmus\Otog" "Hsap\FCGBP, Hsap\MUC5B, Hsap\SSPO, Hsap\MUC5AC, Hsap\MUC2, Hsap\ZAN, Hsap\MUC19, Hsap\OTOGL, Hsap\OTOG, Hsap\MUC6, Hsap\TECTA" DRSC02674 K -0.418021603 0.210328639 -0.620167535 0.565245583 1.794511888 -0.297636765 FBgn0011587 E(top)D105 Enhancer of torpedo D105 http://flybase.org/reports/FBgn0011587 - gene - - - E(top)D105 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084617 aqz aaquetzalli http://flybase.org/reports/FBgn0084617 gene - - - aqz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011093 l(1)Q53 lethal (1) Q53 http://flybase.org/reports/FBgn0011093 FBgn0010210 gene - - - l(1)Q53 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030838 CG5445 - http://flybase.org/reports/FBgn0030838 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000468017 macroautophagy ; GO:0016236 | inferred from biological aspect of ancestor with PANTHER:PTN000468017 autophagosome ; GO:0005776 | inferred from biological aspect of ancestor with PANTHER:PTN000468017 pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN000468017 CG5445 "IPR009060:UBA-like, IPR032350:Next to BRCA1, central domain" CG5445 11-Aug-17 DroID_v2017_08 "Drer\LOC555713, Drer\zgc:101577, Drer\nbr1" - Cele\C36E6.2 Xtro\nbr1 "Mmus\D17Wsu92e, Mmus\Nbr1" "Hsap\NBR1, Hsap\C6orf106" "viable,fertile" FBgn0032663 CG15153 - http://flybase.org/reports/FBgn0032663 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15153 IPR000859:CUB domain CG15153 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264336 CR43792 - http://flybase.org/reports/FBgn0264336 non_protein_coding_gene - - - CR43792 - CR43792 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000393 cur curvoid http://flybase.org/reports/FBgn0000393 - gene - - - cur - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced" wing FBgn0263519 mir-4964 mir-4964 stem loop http://flybase.org/reports/FBgn0263519 miRNA_gene - - - "mir-4964, dme-mir-4964, CR43504" - CR43504 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036585 CG13071 - http://flybase.org/reports/FBgn0036585 protein_coding_gene - - - CG13071 - CG13071 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065262 l(2)SH2085 lethal (2) SH2085 http://flybase.org/reports/FBgn0065262 gene - - - "l(2)SH2085, l(2)SH2 2085" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065840 l(2)SH0327 lethal (2) SH0327 http://flybase.org/reports/FBgn0065840 gene - - - "l(2)SH0327, l(2)SH2 0327" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014309 l(3)neo65 lethal (3) neo65 http://flybase.org/reports/FBgn0014309 - gene - - - l(3)neo65 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040356 CG12498 - http://flybase.org/reports/FBgn0040356 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004343, InterPro:IPR018144 RNA polymerase II C-terminal domain phosphoserine binding ; GO:1990269 | inferred from biological aspect of ancestor with PANTHER:PTN000319032 transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from biological aspect of ancestor with PANTHER:PTN000319032" "histone modification ; GO:0016570 | inferred from electronic annotation with InterPro:IPR018144, InterPro:IPR031102 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from electronic annotation with InterPro:IPR031102" Cdc73/Paf1 complex ; GO:0016593 | inferred from biological aspect of ancestor with PANTHER:PTN000319032 "EG:BACR43E12.1, CG12498" "IPR004343:Plus-3 domain, IPR031102:RNA polymerase-associated protein Rtf1" CG12498 11-Aug-17 DroID_v2017_08 Drer\rtf1 Scer\RTF1 Cele\rtfo-1 Xtro\rtf1 Mmus\Rtf1 Hsap\RTF1 viable FBgn0060696 l(3)S072912 lethal (3) S072912 http://flybase.org/reports/FBgn0060696 gene - - - "0729/12, l(3)S072912" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266059 Su(var)304 - http://flybase.org/reports/FBgn0266059 gene - - - "Su(var)304, 304" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0004503 fs(1)gammaa8 female sterile (1) gammaa8 http://flybase.org/reports/FBgn0004503 - gene - - - fs(1)gammaa8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050353 CG30353 - http://flybase.org/reports/FBgn0050353 protein_coding_gene - - - CG30353 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027616 YT521-B YT521-B http://flybase.org/reports/FBgn0027616 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from direct assay RNA binding ; GO:0003723 | inferred from sequence or structural similarity with PomBase:SPCC736.12c "RNA metabolic process ; GO:0016070 | inferred from sequence or structural similarity with PomBase:SPCC736.12c,RGD:621706 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype sex determination ; GO:0007530 | inferred from genetic interaction with Sxl" "nuclear body ; GO:0016604 | inferred from sequence or structural similarity with PomBase:SPCC736.12c,RGD:621706 nucleus ; GO:0005634 | inferred from direct assay" "dYT521-B, CG12076, BcDNA:GH01918, YT521-B, YT521" IPR007275:YTH domain CG12076 11-Aug-17 DroID_v2017_08 "Drer\ythdf1, Drer\ythdc1, Drer\ythdf3, Drer\ythdf2" Scer\PHO92 Cele\F52B5.3 "Xtro\ythdf3, Xtro\ythdc1, Xtro\ythdc2" "Mmus\Ythdc1, Mmus\Ythdc2, Mmus\Ythdf2, Mmus\Ppp1r10, Mmus\Ythdf1, Mmus\Ythdf3" "Hsap\YTHDC1, Hsap\YTHDF1, Hsap\YTHDF3, Hsap\YTHDF2" "visible,viable" eye DRSC08141 I 3.166926293 -1.195285742 -0.31178111 0.010607154 1.064379101 0.825103842 FBgn0037502 wa-cup walker cup http://flybase.org/reports/FBgn0037502 protein_coding_gene - - - "CG10113, wa-cup" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG10113 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267786 CR46117 - http://flybase.org/reports/FBgn0267786 non_protein_coding_gene - - - CR46117 - CR46117 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032002 CG8353 - http://flybase.org/reports/FBgn0032002 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 cytidine deaminase activity ; GO:0004126 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 cytidine deamination ; GO:0009972 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 CG8353 "IPR002125:Cytidine and deoxycytidylate deaminases, zinc-binding, IPR006262:Cytidine deaminase, homotetrameric, IPR016192:APOBEC/CMP deaminase, zinc-binding, IPR016193:Cytidine deaminase-like" CG8353 11-Aug-17 DroID_v2017_08 "Drer\zgc:103586, Drer\cda" Scer\CDD1 "Cele\cdd-1, Cele\cdd-2" - "Mmus\Gm15114, Mmus\Maged1, Mmus\Maged2, Mmus\Cda, Mmus\Tro" "Hsap\MAGED2, Hsap\TRO, Hsap\MAGED4, Hsap\CDA, Hsap\MAGED1, Hsap\MAGED4B" "viable,visible" trichogen cell FBgn0051561 Osi16 Osiris 16 http://flybase.org/reports/FBgn0051561 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG31561, CG10314, Osi16" IPR012464:Protein of unknown function DUF1676 CG31561 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065146 l(3)SH082 lethal (3) SH082 http://flybase.org/reports/FBgn0065146 gene - - - "l(3)SH082, l(2)SH3 082" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043555 Su(ro[DOM])345 Su(ro[DOM])345 http://flybase.org/reports/FBgn0043555 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])345 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,somatic clone" FBgn0060834 l(3)S049906c lethal (3) S049906c http://flybase.org/reports/FBgn0060834 gene - - - "0499/06, l(3)S049906c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001918 l(2)25Be lethal (2) 25Be http://flybase.org/reports/FBgn0001918 - gene - - - "jf14, l(2)jf14, l(2)25Be" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044492 DTD46.5 DTD46.5 http://flybase.org/reports/FBgn0044492 gene - - - DTD46.5 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265458 CR44358 - http://flybase.org/reports/FBgn0265458 non_protein_coding_gene - - - CR44358 - CR44358 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020337 anon-65Ba anon-65Ba http://flybase.org/reports/FBgn0020337 - gene - - - "x, anon-65Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060975 l(3)S028929b lethal (3) S028929b http://flybase.org/reports/FBgn0060975 gene - - - "0289/29, l(3)S028929b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0026187 pskl pop-sickle http://flybase.org/reports/FBgn0026187 - gene - - - "pskl, CG18803" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037224 TwdlF TweedleF http://flybase.org/reports/FBgn0037224 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from direct assay chitin-based cuticle development ; GO:0040003 | inferred from expression pattern proteinaceous extracellular matrix ; GO:0005578 | inferred from direct assay "TwdlF, CG14639" IPR004145:Domain of unknown function DUF243 CG14639 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085536 CG40924 - http://flybase.org/reports/FBgn0085536 protein_coding_gene - - - CG40924 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015607 Ca-‘±2 Ca2+-channel-protein-‘±2-subunit http://flybase.net/reports/FBgn0015607.html gene 0005245=voltage-gated calcium channel activity "0005886=plasma membrane, 0005891=voltage-gated calcium channel complex" DmCa1alpha2 11-Aug-17 DroID_v2017_08 FBgn0030873 CG15814 - http://flybase.org/reports/FBgn0030873 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000334121 zinc ion binding ; GO:0008270 | inferred from sequence model endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from biological aspect of ancestor with PANTHER:PTN000334121 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000334121 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000334121 Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000334121 CG15814 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15814 11-Aug-17 DroID_v2017_08 "Drer\rnf175, Drer\rnf121, Drer\syvn1" - Cele\rnf-121 Xtro\rnf121 Mmus\Rnf121 "Hsap\RNF175, Hsap\RNF121" viable FBgn0030000 CG2260 - http://flybase.org/reports/FBgn0030000 protein_coding_gene - "neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000363163" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000363163 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000363163 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000363163 CG2260 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR012952:BING4, C-terminal domain, IPR019775:WD40 repeat, conserved site" CG2260 11-Aug-17 DroID_v2017_08 Drer\wdr46 Scer\UTP7 Cele\wdr-46 Xtro\wdr46 Mmus\Wdr46 Hsap\WDR46 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0038247 Cad88C Cadherin 88C http://flybase.org/reports/FBgn0038247 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 open tracheal system development ; GO:0007424 | inferred from genetic interaction with shg cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR020894 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "DCad88C, CG3389, CT11389, Cad88C, Dm Cad88C, cad88C" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site" CG3389 11-Aug-17 DroID_v2017_08 "Drer\dchs1b, Drer\si:ch211-186j3.6, Drer\fat1a, Drer\fat3a, Drer\fat1b, Drer\dchs1a, Drer\cdhr1a, Drer\cdh23, Drer\cdhr2, Drer\si:dkey-22o22.2, Drer\fat2" - "Cele\cdh-8, Cele\cdh-9" "Xtro\fat4, Xtro\dchs2, Xtro\fat1, Xtro\cdhr2" "Mmus\Pcdhb20, Mmus\Cdhr2, Mmus\Fat1, Mmus\Fat3, Mmus\Dchs1, Mmus\Fat2, Mmus\Cdh23" "Hsap\CDH23, Hsap\FAT2, Hsap\DCHS2, Hsap\FAT4, Hsap\DLK2, Hsap\CDHR2, Hsap\FAT1, Hsap\DCHS1, Hsap\PCDHB5, Hsap\FAT3" viable FBgn0021965 l(2)k10105 lethal (2) k10105 http://flybase.org/reports/FBgn0021965 - gene - - - l(2)k10105 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" lysosome & larval fat body | somatic clone | cell autonomous FBgn0038261 CG14856 - http://flybase.org/reports/FBgn0038261 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG14856 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG14856 11-Aug-17 DroID_v2017_08 "Drer\slc22a21, Drer\slc22a5" "Scer\HXT2, Scer\GIT1, Scer\PHO84, Scer\HXT5, Scer\HXT9" "Cele\C53B4.1, Cele\B0361.11, Cele\oct-1, Cele\ZK892.3, Cele\B0252.3, Cele\Y57G11C.23, Cele\T22F7.1, Cele\C06H5.6, Cele\Y51A2D.18, Cele\Y66D12A.13, Cele\C46C2.2" - "Mmus\Slc22a21, Mmus\Slc22a5, Mmus\Slc22a4" "Hsap\SLC22A5, Hsap\SLC22A4" viable FBgn0024204 ol4 oocyte localisation 4 http://flybase.org/reports/FBgn0024204 - gene - - - ol4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039159 mRpS24 mitochondrial ribosomal protein S24 http://flybase.org/reports/FBgn0039159 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AI086409 inferred from sequence or structural similarity with EMBL:AI870515 inferred from sequence or structural similarity with EMBL:AW022634 inferred from sequence or structural similarity with EMBL:W46469 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82650 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q2M2T7 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82650 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:Q2M2T7 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AI086409 inferred from sequence or structural similarity with EMBL:AI870515 inferred from sequence or structural similarity with EMBL:AW022634 inferred from sequence or structural similarity with EMBL:W46469 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with EMBL:AI086409 inferred from sequence or structural similarity with EMBL:AI870515 inferred from sequence or structural similarity with EMBL:AW022634 inferred from sequence or structural similarity with EMBL:W46469 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q2M2T7 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82650 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "MRP-S24, CG13608, MrpS24, mRpS24" "IPR026146:28S ribosomal protein S24, mitochondrial" CG13608 11-Aug-17 DroID_v2017_08 Drer\mrps24 - Cele\mrps-24 Xtro\mrps24 Mmus\Mrps24 Hsap\MRPS24 FBgn0267230 CR45670 - http://flybase.org/reports/FBgn0267230 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR45670 - CR45670 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037135 CG7414 - http://flybase.org/reports/FBgn0037135 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000325517 ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000325517 tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000325517 mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000325517 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC:3254 regulation of translation ; GO:0006417 | inferred from sequence or structural similarity with HGNC:3254 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:3254 cytosolic small ribosomal subunit ; GO:0022627 | inferred from biological aspect of ancestor with PANTHER:PTN000325517 "anon-WO0118547.243, CG7414, eIF2A" "IPR011387:Translation initiation factor 2A, IPR013979:Translation initiation factor, beta propellor-like domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7414 11-Aug-17 DroID_v2017_08 Drer\eif2a Scer\YGR054W Cele\E04D5.1 Xtro\eif2a Mmus\Eif2a Hsap\EIF2A "viable,fertile" FBgn0267589 CR45927 - http://flybase.org/reports/FBgn0267589 non_protein_coding_gene - - - "CR45927, Mgn3598" - CR45927 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084006 CG41441 - http://flybase.org/reports/FBgn0084006 protein_coding_gene - - - CG41441 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032032 CG17294 - http://flybase.org/reports/FBgn0032032 protein_coding_gene inorganic diphosphatase activity ; GO:0004427 | inferred from sequence or structural similarity with HGNC:30042 phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 dephosphorylation ; GO:0016311 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 phosphate-containing compound metabolic process ; GO:0006796 | inferred from sequence or structural similarity with HGNC:30042 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:30042 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:30042 "CG17294, Phos17294, 15010468" "IPR006355:HAD-superfamily hydrolase, subfamily IIA, hypothetical 2, IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG17294 11-Aug-17 DroID_v2017_08 "Drer\ier3ip1, Drer\hdhd2, Drer\lhpp" - "Cele\K08B12.3, Cele\C13C4.4" "Xtro\ier3ip1, Xtro\hdhd2" "Mmus\Ier3ip1, Mmus\Hdhd2, Mmus\Lhpp" "Hsap\IER3IP1, Hsap\LHPP, Hsap\HDHD2" viable FBgn0020791 prn prunus http://flybase.org/reports/FBgn0020791 - gene - - - prn - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0052832 CG32832 - http://flybase.org/reports/FBgn0052832 protein_coding_gene pyruvate transmembrane transporter activity ; GO:0050833 | inferred from biological aspect of ancestor with PANTHER:PTN000365945 mitochondrial pyruvate transmembrane transport ; GO:1902361 | inferred from biological aspect of ancestor with PANTHER:PTN000365945 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000365945 "bs21e09.y1, NEST:bs21e09, NEST:bs10d12, CG32832" IPR005336:Mitochondrial pyruvate carrier CG32832 11-Aug-17 DroID_v2017_08 "Drer\zgc:103678, Drer\mpc2" "Scer\MPC2, Scer\MPC3" Cele\F53F10.3 Xtro\mpc2 Mmus\Mpc2 Hsap\MPC2 viable FBgn0010126 l(1)M54 lethal (1) M54 http://flybase.org/reports/FBgn0010126 - gene - - - l(1)M54 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003091 Pkc53E Protein C kinase 53E http://flybase.org/reports/FBgn0003091 FBgn0034167 protein_coding_gene "protein kinase C activity ; GO:0004697 | inferred from electronic annotation with InterPro:IPR014375 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR014375, InterPro:IPR017441, InterPro:IPR017892 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR014375 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein kinase C activity ; GO:0004697 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay" protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 positive regulation of clathrin-dependent endocytosis ; GO:2000370 | inferred from genetic interaction with inaC protein phosphorylation ; GO:0006468 | inferred from direct assay intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with inaC "PKC-53B, PKC-53E, PKC, PKC 53B, CG6622, PKC 53E, dPKC53E(br), Dpkc1, PKC1, DPKC, dPKC, Pkc1, Pkc53E, PKC53E, pkc53e, PK-C, PKC53e" "IPR000008:C2 domain, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR014375:Protein kinase C, alpha/beta/gamma types, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal, IPR020454:Diacylglycerol/phorbol-ester binding" CG6622 11-Aug-17 DroID_v2017_08 "Drer\pkn1b, Drer\si:ch211-14c7.2, Drer\zgc:153916, Drer\prkca, Drer\pkn1a, Drer\prkcq, Drer\prkcda, Drer\pimr112, Drer\prkcbb, Drer\pkn2, Drer\sgk494b, Drer\prkcha, Drer\pkn3, Drer\prkcea, Drer\prkcba, Drer\si:ch73-374l24.1, Drer\prkchb, Drer\prkcg, Drer\sgk494a, Drer\prkceb" Scer\PKC1 "Cele\pkc-1, Cele\pkc-2, Cele\pkn-1, Cele\tpa-1" "Xtro\LOC100493742, Xtro\prkce, Xtro\gpha2, Xtro\prkch, Xtro\prkcg, Xtro\pkn1, Xtro\tnfrsf1a, Xtro\prkcb, Xtro\prkcq, Xtro\pkn3, Xtro\prkca, Xtro\prkcd" "Mmus\Doc2b, Mmus\Prx, Mmus\Prkce, Mmus\Sprr1b, Mmus\D130040H23Rik, Mmus\Prkcg, Mmus\Prkca, Mmus\Prkcq, Mmus\Pkn2, Mmus\Prkch, Mmus\Gm5113, Mmus\BC030499, Mmus\Prkcb, Mmus\Pkn3, Mmus\Prkcd, Mmus\Pkn1, Mmus\Sprr1a" "Hsap\PKN2, Hsap\PKN3, Hsap\PRKCE, Hsap\PRKCH, Hsap\PRKCD, Hsap\PRX, Hsap\DOC2B, Hsap\PRKCA, Hsap\PRKCQ, Hsap\PRKCG, Hsap\PRKCB, Hsap\SGK494, Hsap\PKN1" adult stage " retina

, adult brain

, adult head

" "visible,viable,fertile,size defective,dominant" "wing vein,ectopic,wing margin,wing blade" FBgn0061169 l(1)14Bc lethal (1) 14Bc http://flybase.org/reports/FBgn0061169 gene - - - l(1)14Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034727 mRpS29 mitochondrial ribosomal protein S29 http://flybase.org/reports/FBgn0034727 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P51398 structural constituent of ribosome ; GO:0003735 | traceable author statement apoptotic process ; GO:0006915 | inferred from electronic annotation with InterPro:IPR008092 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P51398 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P51398 "DAP3, MRP-S29, CG3633, anon-WO0118547.102, mRpS29" "IPR008092:Ribosomal protein S29, mitochondrial, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019368:Ribosomal protein S23/S29, mitochondrial" CG3633 11-Aug-17 DroID_v2017_08 Drer\dap3 Scer\RSM23 Cele\dap-3 Xtro\dap3 Mmus\Dap3 Hsap\DAP3 "viable,lethal,recessive" FBgn0002816 ms(2)1R male sterile (2) 1R http://flybase.org/reports/FBgn0002816 - gene - - - ms(2)1R - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0263499 CR43488 - http://flybase.org/reports/FBgn0263499 non_protein_coding_gene - - - CR43488 - CR43488 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264284 Su(Mir)1E3-2 - http://flybase.org/reports/FBgn0264284 gene - - - Su(Mir)1E3-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile" FBgn0028332 l(1)G0285 lethal (1) G0285 http://flybase.org/reports/FBgn0028332 gene - - - l(1)G0285 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal,recessive" FBgn0022757 Wmc5 Wee-Mik-Complementing 5 http://flybase.org/reports/FBgn0022757 - gene - - - "WMC5, Wmc5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031760 Tsp26A Tetraspanin 26A http://flybase.org/reports/FBgn0031760 protein_coding_gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG9093, Dm.Tsp26A, Tsp26A" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG9093 11-Aug-17 DroID_v2017_08 "Drer\tspan5b, Drer\tspan5a, Drer\LOC799194, Drer\tspan33b, Drer\tspan14, Drer\zgc:113223, Drer\tspan15, Drer\zgc:110329, Drer\tspan17" - Cele\tsp-12 "Xtro\tspan33, Xtro\tspan17, Xtro\tspan14, Xtro\tspan15, Xtro\tspan5" "Mmus\Tspan14, Mmus\Tspan33, Mmus\Tspan15, Mmus\Tspan5, Mmus\Tspan10, Mmus\Tspan17" "Hsap\TSPAN17, Hsap\TSPAN15, Hsap\TSPAN14, Hsap\TSPAN10, Hsap\TSPAN5, Hsap\TSPAN33" viable "sensory mother cell,somatic clone,supernumerary" FBgn0266721 gammaSnap2 gamma Soluble NSF attachment protein 2 http://flybase.org/reports/FBgn0266721 protein_coding_gene soluble NSF attachment protein activity ; GO:0005483 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 soluble NSF attachment protein activity ; GO:0005483 | non-traceable author statement syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 neurotransmitter secretion ; GO:0007269 | non-traceable author statement intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 membrane fusion ; GO:0061025 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 synaptic vesicle priming ; GO:0016082 | non-traceable author statement vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement "CG6208, gammaSnap2, gammaSNAP, gammaSnap-2, SNAP-31" "IPR000744:NSF attachment protein, IPR011990:Tetratricopeptide-like helical domain" CG6208 11-Aug-17 DroID_v2017_08 "Drer\napg, Drer\napga" - "Cele\Y59A8B.25, Cele\Y59A8B.8" Xtro\napg Mmus\Napg Hsap\NAPG FBgn0016738 SR3-8 SR3-8 http://flybase.org/reports/FBgn0016738 - gene - - - SR3-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001882 l(1)YL21 lethal (1) YL21 http://flybase.org/reports/FBgn0001882 - gene - - - l(1)YL21 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262960 CG43271 - http://flybase.org/reports/FBgn0262960 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43271, lincRNA.174" - CG43271 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022985 qkr58E-2 quaking related 58E-2 http://flybase.org/reports/FBgn0022985 - protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG5821, qrk58E-2, qkr58E-2, qkr58e-2" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG5821 11-Aug-17 DroID_v2017_08 "Drer\khdrbs1b, Drer\khdrbs1a, Drer\khdrbs3, Drer\qkib, Drer\khdrbs2, Drer\qkia, Drer\qki2" Scer\MSL5 Cele\asd-2 "Xtro\qki, Xtro\khdrbs2, Xtro\khdrbs1, Xtro\khdrbs3" "Mmus\Khdrbs3, Mmus\Qk, Mmus\Khdrbs2, Mmus\Khdrbs1" "Hsap\QKI, Hsap\KHDRBS2, Hsap\KHDRBS3, Hsap\KHDRBS1" viable FBgn0085504 CG40626 - http://flybase.org/reports/FBgn0085504 protein_coding_gene - - - CG40626 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033903 CG8323 - http://flybase.org/reports/FBgn0033903 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640628 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 CG8323 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG8323 11-Aug-17 DroID_v2017_08 "Drer\slc25a35, Drer\slc25a34, Drer\slc25a14" "Scer\DIC1, Scer\OAC1" "Cele\misc-1, Cele\slc-25A10" "Xtro\slc25a34, Xtro\slc25a30" "Mmus\Slc25a30, Mmus\Slc25a11, Mmus\Slc25a35, Mmus\Slc25a14, Mmus\Slc25a34, Mmus\Slc25a10" "Hsap\SLC25A14, Hsap\SLC25A35, Hsap\SLC25A34, Hsap\SLC25A10, Hsap\SLC25A30, Hsap\SLC25A11" viable FBgn0265788 CR44577 - http://flybase.org/reports/FBgn0265788 non_protein_coding_gene - - - CR44577 - CR44577 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037720 CG8312 - http://flybase.org/reports/FBgn0037720 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of protein phosphorylation ; GO:0001933 | inferred from sequence or structural similarity with HGNC:26084 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with HGNC:26084 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:26084 CG8312 "IPR011993:PH domain-like, IPR033930:FAM43A/B, phosphotyrosine-binding domain, IPR006020:PTB/PI domain" CG8312 11-Aug-17 DroID_v2017_08 "Drer\ldlrap1b, Drer\fam43a, Drer\fam43b" - Cele\F52D10.2 "Xtro\pid1, Xtro\ldlrap1, Xtro\fam43b" "Mmus\Pid1, Mmus\Fam43a, Mmus\Fam43b" "Hsap\FAM43B, Hsap\FAM43A, Hsap\PID1" FBgn0001588 l(1)carot5 lethal (1) carot5 http://flybase.org/reports/FBgn0001588 - gene - - - l(1)carot5 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0058461 CR40461 - http://flybase.org/reports/FBgn0058461 pseudogene_attribute - - - "CG40461, CR40461, His2B:CG40461" - CR40461 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259262 EP-694 - http://flybase.org/reports/FBgn0259262 gene - - - EP-694 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,planar polarity defective" wing FBgn0060748 l(3)S065208 lethal (3) S065208 http://flybase.org/reports/FBgn0060748 gene - - - "0652/08, l(3)S065208" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0035473 mge maggie http://flybase.org/reports/FBgn0035473 protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001754335 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with SGD:S000005075 protein import into mitochondrial outer membrane ; GO:0045040 | inferred from biological aspect of ancestor with PANTHER:PTN001754335 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN001754335 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from sequence or structural similarity with SGD:S000005075 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from biological aspect of ancestor with PANTHER:PTN001754335 mitochondrion ; GO:0005739 | inferred from direct assay integral component of mitochondrial outer membrane ; GO:0031307 | inferred from biological aspect of ancestor with PANTHER:PTN001754335 "l(3)63Fc, l(3)SH3, CG14981, BcDNA:LP07226, mge" IPR005683:Mitochondrial import receptor subunit Tom22 CG14981 11-Aug-17 DroID_v2017_08 Drer\tomm22 Scer\TOM22 Cele\tomm-22 Xtro\tomm22 Mmus\Tomm22 Hsap\TOMM22 "hypoactive,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" DRSC08721 E -0.77990629 0.393829993 -1.711823052 0.078029798 -0.008625811 -0.621413854 FBgn0004165 l(2)51F lethal (2) 51F http://flybase.org/reports/FBgn0004165 - gene - - - l(2)51F - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265446 CR44346 - http://flybase.org/reports/FBgn0265446 non_protein_coding_gene - - - "CR44346, lincRNA.171" - CR44346 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053729 snmRNA:430:CR33729 snmRNA:430:CR33729 http://flybase.org/reports/FBgn0053729 non_protein_coding_gene - - - "CR33729, snmRNA:430:CR33729" - CR33729 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039466 CG5521 - http://flybase.org/reports/FBgn0039466 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000006939 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with RapGAP1 regulation of small GTPase mediated signal transduction ; GO:0051056 | inferred from electronic annotation with InterPro:IPR000331 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000006939 "EP3527, CG5521, FBpp0084441" "IPR000331:Rap GTPase activating protein domain, IPR016024:Armadillo-type fold" CG5521 11-Aug-17 DroID_v2017_08 "Drer\sipa1l1, Drer\ralgapa2, Drer\si:ch211-182d3.1, Drer\si:dkey-166d12.2, Drer\sipa1l2, Drer\rap1gap2a, Drer\zmp:0000001168, Drer\LOC101882292, Drer\sipa1l3" - Cele\hgap-1 "Xtro\garnl3, Xtro\sipa1l1, Xtro\rap1gap, Xtro\rap1gap2, Xtro\ralgapa1" "Mmus\Ralgapa2, Mmus\Garnl3, Mmus\Sipa1, Mmus\Rap1gap2, Mmus\Sipa1l1, Mmus\Rap1gap, Mmus\Sipa1l3, Mmus\Sipa1l2, Mmus\Ralgapa1" "Hsap\RALGAPA2, Hsap\SIPA1L2, Hsap\SIPA1L3, Hsap\RALGAPA1, Hsap\SIPA1L1, Hsap\RAP1GAP2, Hsap\GARNL3, Hsap\SIPA1, Hsap\RAP1GAP" viable DRSC15828 E 0.576511726 -0.132603265 0.926451329 -2.493724775 -0.442849858 0.463312455 FBgn0065663 l(2)SH0707 lethal (2) SH0707 http://flybase.org/reports/FBgn0065663 gene - - - l(2)SH0707 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001006 Fs(2)X10 Female sterile (2) X10 http://flybase.org/reports/FBgn0001006 - gene - - - Fs(2)X10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,dominant" egg FBgn0065070 snoRNA:291 snoRNA:291 http://flybase.org/reports/FBgn0065070 snoRNA_gene - - - "Dm-291, snoR291, CR33638, snoRNA:291, DmOr_cd7, SnoR291" - CR33638 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033129 Tsp42Eh Tetraspanin 42Eh http://flybase.org/reports/FBgn0033129 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "CG12844, Dm.Tsp42Eh, Tsp42Eh" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12844 11-Aug-17 DroID_v2017_08 "Drer\cd63, Drer\tspan33a, Drer\tspan33b, Drer\zgc:113223" - "Cele\tsp-16, Cele\tsp-5, Cele\tsp-4, Cele\tsp-7" Xtro\cd63 "Mmus\Cd63, Mmus\Tspan32, Mmus\Tspan33" "Hsap\CD63, Hsap\TSPAN33, Hsap\TSPAN32" "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0028526 CG15293 - http://flybase.org/reports/FBgn0028526 protein_coding_gene - - extracellular region ; GO:0005576 | inferred from direct assay "CG15293, CT35241, BG:DS01759.2, HL03474" - CG15293 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025750 l(3)93Dm lethal (3) 93Dm http://flybase.org/reports/FBgn0025750 - gene - - - l(3)93Dm - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030409 CG15728 - http://flybase.org/reports/FBgn0030409 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15728 - CG15728 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0001856 l(1)tsUC88 lethal (1) tsUC88 http://flybase.org/reports/FBgn0001856 - gene - - - l(1)tsUC88 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0028737 eEF1beta eukaryotic translation elongation factor 1 beta http://flybase.org/reports/FBgn0028737 protein_coding_gene "translation elongation factor activity ; GO:0003746 | inferred from electronic annotation with InterPro:IPR001326, InterPro:IPR014038 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity" "translational elongation ; GO:0006414 | inferred from electronic annotation with InterPro:IPR001326, InterPro:IPR014038 translational elongation ; GO:0006414 | inferred from sequence or structural similarity" "eukaryotic translation elongation factor 1 complex ; GO:0005853 | inferred from electronic annotation with InterPro:IPR001326, InterPro:IPR014038 cytosol ; GO:0005829 | non-traceable author statement lipid particle ; GO:0005811 | inferred from direct assay eukaryotic translation elongation factor 1 complex ; GO:0005853 | inferred from sequence or structural similarity" "154264_at, CG6341, Elf 1 beta, BcDNA.LD24492, Ef1beta, EG:EG0003.7, BcDNA:LD24492, eEF1beta" "IPR001326:Translation elongation factor EF1B, beta/delta chains, conserved site, IPR010987:Glutathione S-transferase, C-terminal-like, IPR014038:Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain, IPR014717:Translation elongation factor EF1B/ribosomal protein S6, IPR018940:Elongation factor 1 beta central acidic region, eukaryote" CG6341 11-Aug-17 DroID_v2017_08 "Drer\eef1b2, Drer\eef1da, Drer\eef1db" Scer\EFB1 "Cele\eef-1B.1, Cele\eef-1B.2" "Xtro\eef1b2, Xtro\eef1d" "Mmus\Eef1b2, Mmus\Eef1d" "Hsap\EEF1B2, Hsap\EEF1D" "viable,fertile,visible,lethal - all die before end of pupal stage,some die during pupal stage" "dorsocentral bristle,scutellar bristle" FBgn0027152 l(3)64Da lethal (3) 64Da http://flybase.org/reports/FBgn0027152 - gene - - - l(3)64Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002610 M(3)62A Minute (3) 62A http://flybase.org/reports/FBgn0002610 - gene - - - "M(3)LS1, M(3)62A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030756 CG9903 - http://flybase.org/reports/FBgn0030756 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002657 CG9903 "IPR002657:Bile acid:sodium symporter/arsenical resistance protein Acr3, IPR004710:Bile acid:sodium symporter" CG9903 11-Aug-17 DroID_v2017_08 "Drer\slc10a3, Drer\slc10a4, Drer\slc10a2, Drer\slc10a1" - Cele\Y71G10AR.4 "Xtro\slc10a2, Xtro\slc10a6, Xtro\slc10a4" "Mmus\Slc10a4, Mmus\Slc10a5, Mmus\Slc10a2, Mmus\Slc10a3, Mmus\Slc10a1, Mmus\Gm5868, Mmus\Slc10a6" "Hsap\SLC10A5, Hsap\SLC10A2, Hsap\SLC10A1, Hsap\SLC10A3, Hsap\SLC10A4, Hsap\SLC10A6" viable FBgn0283639 mir-9369 mir-9369 stem loop http://flybase.org/reports/FBgn0283639 miRNA_gene - - - "mir-9369, CR46290, dme-mir-9369" - CR46290 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044393 Scim35 Sensitized chromosome inheritance modifier 35 http://flybase.org/reports/FBgn0044393 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim35 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0047314 CR31972 - http://flybase.org/reports/FBgn0047314 non_protein_coding_gene - - - "BcDNA:GH10270, CR31972, MRE27" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034225 veil veil http://flybase.org/reports/FBgn0034225 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR006146 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR006146 5'-nucleotidase activity ; GO:0008253 | inferred from direct assay "nucleotide catabolic process ; GO:0009166 | inferred from electronic annotation with InterPro:IPR006179, InterPro:IPR008334" - "CG4827, NT5E-1, veil" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006146:5'-Nucleotidase, conserved site, IPR006179:5'-Nucleotidase/apyrase, IPR008334:5'-Nucleotidase, C-terminal, IPR029052:Metallo-dependent phosphatase-like" CG4827 11-Aug-17 DroID_v2017_08 Drer\nt5e Scer\YHR202W - Xtro\nt5e "Mmus\Nt5e, Mmus\4933425L06Rik" Hsap\NT5E "wing,posterior compartment" FBgn0266574 tRNA:Thr-TGT-2-4 transfer RNA:Threonine-TGT 2-4 http://flybase.org/reports/FBgn0266574 tRNA_gene ACA codon-amino acid adaptor activity ; GO:0033439 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033439 cytosol ; GO:0005829 | inferred by curator from GO:0033439 "CR30261, CR30505, tRNA:CR30505, tRNA:T3:47F, tRNA:T:TGT:AE002787-a, tRNA:thr3:47F, tRNA[[Thr]], tRNA[Thr][[3]], AE002787.trna24-ThrTGT, CR45107, chr2R.trna83-ThrTGT, tRNA-Thr-TGT-2-4, tRNA:Thr-TGT-2-4, tRNA:CR45107, ACA" - CR45107 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030306 Spase25 Spase 25-subunit http://flybase.org/reports/FBgn0030306 protein_coding_gene peptidase activity ; GO:0008233 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000317824 signal peptide processing ; GO:0006465 | inferred from biological aspect of ancestor with PANTHER:PTN000317824 protein targeting to ER ; GO:0045047 | inferred from biological aspect of ancestor with PANTHER:PTN000317824 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009582 endomembrane system ; GO:0012505 | inferred from direct assay signal peptidase complex ; GO:0005787 | inferred from biological aspect of ancestor with PANTHER:PTN000317824 "CG1751, Spase25, CG1571" IPR009582:Signal peptidase complex subunit 2 CG1751 11-Aug-17 DroID_v2017_08 Drer\spcs2 Scer\SPC2 Cele\hpo-21 Xtro\spcs2 Mmus\Spcs2 Hsap\SPCS2 "lethal,recessive" FBgn0265648 CR44455 - http://flybase.org/reports/FBgn0265648 non_protein_coding_gene - - - CR44455 - CR44455 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265817 CR44606 - http://flybase.org/reports/FBgn0265817 non_protein_coding_gene - - - "lincRNA.208, CR44606" - CR44606 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082684 E(ftz)2828 E(ftz)2828 http://flybase.org/reports/FBgn0082684 gene - - - "2828, E(ftz)2828" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025697 santa-maria scavenger receptor acting in neural tissue and majority of rhodopsin is absent http://flybase.org/reports/FBgn0025697 FBgn0031915 protein_coding_gene - salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern phototransduction ; GO:0007602 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype carotenoid metabolic process ; GO:0016116 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern thermotaxis ; GO:0043052 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "CK01577, BEST:CK01577, santa-maria, CG12789, santa maria, Santa Maria" IPR002159:CD36 family CG12789 11-Aug-17 DroID_v2017_08 "Drer\cd36, Drer\scarb2, Drer\scarb1, Drer\LOC564077" - "Cele\scav-3, Cele\scav-1, Cele\scav-2, Cele\scav-4" "Xtro\scarb1, Xtro\scarb2, Xtro\cd36" "Mmus\Scarb2, Mmus\Scarb1, Mmus\Cd36" "Hsap\CD36, Hsap\SCARB1, Hsap\SCARB2" "viable,neurophysiology defective,thermotaxis behavior defective,auditory perception defective" FBgn0069927 CG41124 - http://flybase.org/reports/FBgn0069927 protein_coding_gene - - - CG41124 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051030 CG31030 - http://flybase.org/reports/FBgn0051030 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR008388 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | inferred from electronic annotation with InterPro:IPR008388" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008388 "proton-transporting V-type ATPase, V1 domain ; GO:0033180 | inferred from electronic annotation with InterPro:IPR008388" "anon-EST:Posey81, CG2176, BcDNA:RH09162, CG31030" "IPR008388:ATPase, V1 complex, subunit S1" CG31030 11-Aug-17 DroID_v2017_08 "Drer\atp6ap1lb, Drer\atp6ap1la, Drer\atp6ap1b, Drer\atp6ap1a" - Cele\vha-19 Xtro\atp6ap1.2 "Mmus\Atp6ap1, Mmus\Atp6ap1l" "Hsap\ATP6AP1L, Hsap\ATP6AP1" viable FBgn0011879 tRNA:Ala-TGC-2-1 transfer RNA:Alanine-TGC 2-1 http://flybase.org/reports/FBgn0011879 "FBgn0050233, FBgn0060273" tRNA_gene GCA codon-amino acid adaptor activity ; GO:0033455 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033455 cytosol ; GO:0005829 | inferred by curator from GO:0033455 "AE002787.trna46-AlaTGC, CR30233, tRNA:A:TGC:AE002787-b, chr2R.trna29-AlaTGC, tRNA-Ala-TGC-2-1, tRNA:Ala-TGC-2-1, tRNA:CR30233, GCA, tRNA[Ala(TGC)]" - CR30233 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005378 x10 x10 http://flybase.org/reports/FBgn0005378 - gene - - - x10 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259248 C649 - http://flybase.org/reports/FBgn0259248 gene - - - C649 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0032419 CG17217 - http://flybase.org/reports/FBgn0032419 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17217 - CG17217 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069326 X-149-3 X-149-3 http://flybase.org/reports/FBgn0069326 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-149-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0261938 mtRNApol mitochondrial RNA polymerase http://flybase.org/reports/FBgn0261938 protein_coding_gene DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with UniProtKB:O00411 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from biological aspect of ancestor with PANTHER:PTN000010146 mitochondrial RNA polymerase core promoter sequence-specific DNA binding ; GO:0000997 | inferred from biological aspect of ancestor with PANTHER:PTN000010147 "transcription, DNA-templated ; GO:0006351 | inferred from sequence or structural similarity with UniProtKB:O00411 transcription from mitochondrial promoter ; GO:0006390 | inferred from biological aspect of ancestor with PANTHER:PTN000010146" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O00411 mitochondrial DNA-directed RNA polymerase complex ; GO:0034245 | inferred from biological aspect of ancestor with PANTHER:PTN000010147 "mt RNA pol, CG4644, mtRNApol, mtRNA-pol, POLRMT, mtRNAP" "IPR024075:DNA-directed RNA polymerase, helix hairpin domain, IPR029262:DNA-directed RNA polymerase, N-terminal, IPR002092:DNA-directed RNA polymerase, phage-type, IPR002885:Pentatricopeptide repeat" CG4644 11-Aug-17 DroID_v2017_08 Drer\polrmt Scer\RPO41 Cele\rpom-1 Xtro\polrmt Mmus\Polrmt Hsap\POLRMT "decreased cell number,conditional,visible,size defective" "eye disc,conditional,eye" DRSC00660 E -0.362440249 0.30775138 -1.590546869 -0.336535542 0.366524768 0.361129595 FBgn0014189 Hel25E Helicase at 25E http://flybase.org/reports/FBgn0014189 "FBgn0001929, FBgn0008648, FBgn0021910" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000002242 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002242 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from biological aspect of ancestor with PANTHER:PTN000620148 mRNA export from nucleus ; GO:0006406 | inferred from mutant phenotype RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218" nucleus ; GO:0005634 | inferred by curator from GO:0000381 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000002242 microtubule associated complex ; GO:0005875 | inferred from direct assay polytene chromosome ; GO:0005700 | colocalizes_with inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:13917 spliceosomal complex ; GO:0005681 | inferred from biological aspect of ancestor with PANTHER:PTN000620148 nucleus ; GO:0005634 | inferred from direct assay "UAP56, uap56, DmRH4, HEL, CG7269, WM6, hel, jf26, l(2)gdh-12, l(2)jf26, l(2)gdh12, l(2)25Eb, Wm6, Hel, Dbp25F, l(2)k11511, Hel25E, Uap56, sz, HEL25E" "IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7269 11-Aug-17 DroID_v2017_08 "Drer\ddx39ab, Drer\ddx39b, Drer\ddx39aa" Scer\SUB2 Cele\hel-1 "Xtro\ddx39a, Xtro\ddx39b" "Mmus\Ddx39b, Mmus\Ddx39" "Hsap\DDX39A, Hsap\DDX39B" " embryonic stage | gastrula , adult stage && oogenesis stage , larval stage , embryonic stage " " mitotic domain

, follicle cell

, nurse cell

, embryonic/larval salivary gland

" "viable,fertile,lethal,recessive,enhancer of variegation,dominant,wild-type,suppressor of variegation" "adult head,adult thorax,adult abdomen,egg,germline clone,dorsal appendage,egg chamber" DRSC03342 IE 5.410190957 0.401036352 3.24716355 -3.498219858 -0.788941865 -0.750247986 FBgn0265683 CR44490 - http://flybase.org/reports/FBgn0265683 non_protein_coding_gene - - - "lincRNA.102, CR44490" - CR44490 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038878 CG3301 - http://flybase.org/reports/FBgn0038878 protein_coding_gene - - - "CG3301, FOHSDR" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG3301 11-Aug-17 DroID_v2017_08 "Drer\zgc:153724, Drer\dhrs11b, Drer\dhrs11a, Drer\zgc:92630" Scer\YMR226C Cele\H04M03.3 Xtro\dhrs11 Mmus\Dhrs11 Hsap\DHRS11 "viable,fertile" FBgn0029658 CG14269 - http://flybase.org/reports/FBgn0029658 protein_coding_gene - - - CG14269 IPR032007:Protein of unknown function DUF4791 CG14269 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031954 CG14537 - http://flybase.org/reports/FBgn0031954 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT11469, CG14537" IPR032007:Protein of unknown function DUF4791 CG14537 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0012042 AttA Attacin-A http://flybase.org/reports/FBgn0012042 "FBgn0044580, FBgn0064916" protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | non-traceable author statement humoral immune response ; GO:0006959 | inferred from expression pattern response to hyperoxia ; GO:0055093 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern antibacterial humoral response ; GO:0019731 | inferred from expression pattern defense response to bacterium ; GO:0042742 | traceable author statement extracellular space ; GO:0005615 | inferred from direct assay "AttA, att, Att, ATT, attA, Att A, CG10146, att A, BcDNA:LP05763, anon-WO0140519.5, Att-A" "IPR005520:Attacin, N-terminal, IPR005521:Attacin, C-terminal" CG10146 11-Aug-17 DroID_v2017_08 - - - - - - "immune response defective,short lived,conditional,viable,partially lethal - majority die,some die during pupal stage" FBgn0052330 tRNA:Glu-CTC-3-1 transfer RNA:Glutamic acid-CTC 3-1 http://flybase.org/reports/FBgn0052330 tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "CR32330, AE002584.trna3-GluCTC, tRNA:E:CTC:AE002584-a, chr3L.trna3-GluCTC, tRNA:Glu-CTC-3-1, tRNA:CR32330, tRNA-Glu-CTC-3-1, GAG" - CR32330 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020628 Mst57Ca Male-specific transcript 57C http://flybase.org/reports/FBgn0020628 - gene - - - Mst57Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021935 l(2)k10914 lethal (2) k10914 http://flybase.org/reports/FBgn0021935 - gene - - - l(2)k10914 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028300 l(1)G0382 lethal (1) G0382 http://flybase.org/reports/FBgn0028300 gene - - - l(1)G0382 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0028275 l(1)G0430 lethal (1) G0430 http://flybase.org/reports/FBgn0028275 gene - - - l(1)G0430 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0033413 prel preli-like http://flybase.org/reports/FBgn0033413 protein_coding_gene molecular_function ; GO:0003674 | no biological data available dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial crista ; GO:0030061 | inferred from direct assay "CG8806, BcDNA:LD36516, prel" IPR006797:PRELI/MSF1 domain CG8806 11-Aug-17 DroID_v2017_08 "Drer\prelid1b, Drer\prelid1a" Scer\UPS1 Cele\B0334.4 Xtro\prelid1 Mmus\Prelid1 Hsap\PRELID1 "neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,visible" "mitochondrion & dorsal multidendritic neuron ddaC | somatic clone,dendrite & dorsal multidendritic neuron ddaC | somatic clone,mitochondrion & dorsal multidendritic neuron ddaC | somatic cloneppk.1.9,dendrite & dorsal multidendritic neuron ddaC | somatic cloneppk.1.9,dendrite & class IV dendritic arborising neuronppk.1.9,dendrite & abdominal anterior ventral multidendritic neuron vdaappk.1.9,trichogen cell,mesothoracic tergum" FBgn0267033 mamo maternal gene required for meiosis http://flybase.org/reports/FBgn0267033 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay gamete generation ; GO:0007276 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype regulation of chromatin organization ; GO:1902275 | inferred from mutant phenotype sperm chromatin decondensation ; GO:0035041 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay "CG11071, mamo, lincRNA.990, CG45477, CG44132, CG32611, CG34346, CG11075, CG11082, CG11072, CG32606, CR44656" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG45477 11-Aug-17 DroID_v2017_08 "Drer\klf5a, Drer\sp3b, Drer\sp1, Drer\sp3a, Drer\klf5l" "Scer\CRZ1, Scer\ACE2, Scer\SWI5" "Cele\klf-2, Cele\sptf-2, Cele\hinf-1" "Xtro\sp1, Xtro\zbtb43, Xtro\sp5, Xtro\zbtb34" "Mmus\Sp3, Mmus\Klf5, Mmus\Klf10, Mmus\Zfp784, Mmus\Hic2, Mmus\Hic1, Mmus\Sp1, Mmus\Sp5" "Hsap\SP3, Hsap\ZNF784, Hsap\SP5, Hsap\KLF10, Hsap\SP1, Hsap\ZBTB45, Hsap\ZNF311" FBgn0261793 Trf2 TATA box binding protein-related factor 2 http://flybase.org/reports/FBgn0261793 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement chromatin binding ; GO:0003682 | inferred from direct assay transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | inferred by curator from GO:0000979,GO:0045944 RNA polymerase II core promoter sequence-specific DNA binding ; GO:0000979 | inferred from direct assay transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from physical interaction with Dref core promoter binding ; GO:0001047 | inferred from direct assay" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR000814 response to ecdysone ; GO:0035075 | inferred from mutant phenotype pupal development ; GO:0035209 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | traceable author statement spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter ; GO:0060963 | inferred from direct assay inferred from mutant phenotype" female germ cell nucleus ; GO:0001674 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11588 inferred from sequence or structural similarity with SGD:S000000950 polytene chromosome ; GO:0005700 | inferred from direct assay male germ cell nucleus ; GO:0001673 | inferred from direct assay "Trf2, trf2, CG18009, TRF2, dTRF2, p79/TRF2, CG11195, TLF, dTrf2, l(1)G0039, l(1)G0295, l(1)G0425, l(1)G0071, dTRF2S, dTRF2L" "IPR015445:TATA-Box binding protein-like, IPR000814:TATA-box binding protein" CG18009 11-Aug-17 DroID_v2017_08 "Drer\tbpl1, Drer\tbp" Scer\SPT15 Cele\tlf-1 "Xtro\tbpl2, Xtro\tbpl1, Xtro\tbp" "Mmus\Tbpl1, Mmus\Tbpl2, Mmus\Tbp" "Hsap\TBPL1, Hsap\TBPL2, Hsap\TBP" DRSC18727 IEK -2.991479759 -0.51407372 -1.263195336 -2.010648849 0.924045504 3.369782324 FBgn0262007 CG42825 - http://flybase.org/reports/FBgn0262007 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 "CG6640, CG42825, GH19118, anon-WO0140519.30" "IPR020846:Major facilitator superfamily domain, IPR005828:Major facilitator, sugar transporter-like" CG42825 11-Aug-17 DroID_v2017_08 "Drer\slc2a6, Drer\slc2a13b, Drer\slc2a8, Drer\LOC101882338, Drer\slc2a12, Drer\slc2a10" "Scer\HXT13, Scer\GEX1, Scer\MAL11, Scer\SGE1, Scer\HXT2, Scer\HXT5, Scer\VBA5, Scer\MPH3, Scer\HXT16, Scer\HXT15, Scer\YDR387C, Scer\HXT6, Scer\ENB1, Scer\ATR1, Scer\MAL31, Scer\VBA3, Scer\VBA2, Scer\ITR1, Scer\HXT7, Scer\MPH2, Scer\HXT4, Scer\HXT10, Scer\HXT8, Scer\YMR279C, Scer\HXT3, Scer\SNF3, Scer\RGT2, Scer\STL1, Scer\YDL199C, Scer\HXT14, Scer\VBA4, Scer\HXT1, Scer\HXT9, Scer\GAL2, Scer\HXT17, Scer\ITR2, Scer\AZR1, Scer\YFL040W, Scer\GEX2, Scer\VBA1, Scer\HXT11" "Cele\fgt-1, Cele\hmit-1.2" "Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a10, Xtro\slc2a12" "Mmus\Slc2a6, Mmus\Slc2a8, Mmus\Slc2a12, Mmus\Slc2a13, Mmus\Slc2a10" "Hsap\SLC2A13, Hsap\SLC2A6, Hsap\SLC2A12, Hsap\SLC2A8, Hsap\SLC2A10" viable FBgn0012030 l(2)DTS18SP lethal (2) DTS18 Suzuki & Procunier http://flybase.org/reports/FBgn0012030 FBgn0005147 gene - - - "DTS-L18, l(2)DTS18SP" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,recessive" FBgn0051668 CG31668 - http://flybase.org/reports/FBgn0051668 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "CG10879, CG31668, CG31668-PB, dSLC5A12" IPR001734:Sodium/solute symporter CG31668 11-Aug-17 DroID_v2017_08 "Drer\slc5a6a, Drer\si:dkeyp-9d4.5, Drer\slc5a6b, Drer\slc5a1, Drer\slc5a8l, Drer\slc5a3a, Drer\slc5a2, Drer\slc5a8, Drer\slc5a5, Drer\slc5a11, Drer\LOC568338, Drer\slc5a12, Drer\slc5a9" Scer\DUR3 "Cele\ZK822.5, Cele\F52H2.4" "Xtro\slc5a5, Xtro\slc5a2, Xtro\slc5a9, Xtro\slc5a8, Xtro\slc5a1.1, Xtro\slc5a12, Xtro\slc5a11" "Mmus\Slc5a5, Mmus\Slc5a8, Mmus\Slc5a3, Mmus\Slc5a12, Mmus\Slc5a4b, Mmus\Slc5a1, Mmus\Slc5a6, Mmus\Slc5a9, Mmus\Slc5a2, Mmus\Slc5a11, Mmus\Slc5a10, Mmus\Slc5a4a, Mmus\Gm5134" "Hsap\SLC5A10, Hsap\SLC5A11, Hsap\SLC5A12, Hsap\SLC5A5, Hsap\SLC5A1, Hsap\SLC5A9, Hsap\SLC5A4, Hsap\SLC5A6, Hsap\SLC5A8, Hsap\SLC5A2, Hsap\SLC5A3" viable FBgn0036711 CG13727 - http://flybase.org/reports/FBgn0036711 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13727 - CG13727 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035122 mRpL17 mitochondrial ribosomal protein L17 http://flybase.org/reports/FBgn0035122 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AI141700 mitochondrial genome maintenance ; GO:0000002 | inferred from biological aspect of ancestor with PANTHER:PTN001024656 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AI141700 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AI141700 "L17, CG13880, BcDNA:RE43278, mRpL17, mRPL17, mrpL17" IPR000456:Ribosomal protein L17 CG13880 11-Aug-17 DroID_v2017_08 Drer\mrpl17 Scer\MRPL8 Cele\mrpl-17 Xtro\mrpl17 Mmus\Mrpl17 Hsap\MRPL17 "visible,recessive,somatic clone,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,eye disc,trichogen cell" FBgn0082583 tipsy tipsy http://flybase.org/reports/FBgn0082583 gene - behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype - "tipsy, tps, I79" - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0037762 eloF elongase F http://flybase.org/reports/FBgn0037762 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from direct assay fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond courtship behavior ; GO:0007619 | inferred from mutant phenotype pheromone metabolic process ; GO:0042810 | inferred from mutant phenotype very long-chain fatty acid biosynthetic process ; GO:0042761 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "eloF, CG16905" "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG16905 11-Aug-17 DroID_v2017_08 "Drer\elovl4a, Drer\elovl7a, Drer\elovl8a, Drer\elovl7b, Drer\elovl8b, Drer\elovl1b, Drer\elovl1a, Drer\elovl2, Drer\elovl4b, Drer\elovl5" "Scer\ELO2, Scer\ELO1, Scer\ELO3" "Cele\elo-1, Cele\elo-6" "Xtro\elovl1, Xtro\elovl2, Xtro\elovl7, Xtro\elovl5" "Mmus\Elovl7, Mmus\Elovl5, Mmus\Elovl2, Mmus\Elovl1, Mmus\Elovl4" "Hsap\ELOVL2, Hsap\ELOVL5, Hsap\ELOVL4, Hsap\ELOVL1, Hsap\ELOVL7" "courtship behavior defective,mating defective,viable" FBgn0029095 aru arouser http://flybase.org/reports/FBgn0029095 protein_coding_gene - response to ethanol ; GO:0045471 | inferred from direct assay regulation of synapse structure or activity ; GO:0050803 | inferred from direct assay olfactory behavior ; GO:0042048 | inferred from direct assay memory ; GO:0007613 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay "CG4276, aru, EPS8L3" "IPR001452:SH3 domain, IPR013625:Tensin/EPS8 phosphotyrosine-binding domain, IPR011993:PH domain-like, IPR033928:Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain" CG4276 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-89b12.1, Drer\eps8l3b, Drer\si:ch73-70c5.1, Drer\eps8l3a, Drer\eps8l1, Drer\si:dkey-287h13.1, Drer\eps8" - Cele\eps-8 "Xtro\eps8, Xtro\eps8l3" "Mmus\Eps8, Mmus\Eps8l2, Mmus\Eps8l3, Mmus\Eps8l1" "Hsap\EPS8L2, Hsap\EPS8L1, Hsap\EPS8, Hsap\EPS8L3" "smell perception defective,memory defective,chemical sensitive,lethal,chemical resistant,heat sensitive,viable,visible" "bouton,supernumerary,mesothoracic tergum" FBgn0053537 tRNA:Asn-GTT-1-9 transfer RNA:Asparagine-GTT 1-9 http://flybase.org/reports/FBgn0053537 tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "AE002575.trna5-AsnGTT, tRNA:N:GTT:AE002575, tRNA:asn5:60C, CR33537, chr2R.trna49-AsnGTT, tRNA-Asn-GTT-1-9, tRNA:Asn-GTT-1-9, tRNA:N5:60C, AAC" - CR33537 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259989 CG42486 - http://flybase.org/reports/FBgn0259989 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from sequence or structural similarity with HGNC:15464 negative regulation of endopeptidase activity ; GO:0010951 | inferred from sequence or structural similarity with HGNC:15464 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with HGNC:15464 "CG42486, CG42501" IPR002350:Kazal domain CG42486 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-203a12.7, Drer\tmeff2b, Drer\tmeff2a, Drer\tmeff1b" - Cele\ZK813.6 Xtro\tmeff1 "Mmus\Tmeff2, Mmus\Tmeff1" "Hsap\TMEFF1, Hsap\TMEFF2" FBgn0038731 CG11659 - http://flybase.org/reports/FBgn0038731 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 bioluminescence ; GO:0008218 | inferred from electronic annotation with InterPro:IPR027380 - CG11659 "IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site, IPR027380:Luciferase, N-terminal domain, IPR025110:AMP-binding enzyme C-terminal domain" CG11659 11-Aug-17 DroID_v2017_08 "Drer\acsf3, Drer\acsbg1" Scer\PCS60 "Cele\acs-14, Cele\mec-18, Cele\acs-6, Cele\acs-2, Cele\acs-16, Cele\acs-10, Cele\acs-1, Cele\C25G6.3, Cele\acs-7, Cele\acs-9, Cele\C32E8.6" Xtro\acsf3 "Mmus\Acsbg1, Mmus\Acsf3" "Hsap\ACSBG1, Hsap\ACSF2, Hsap\ACSF3" FBgn0034145 CG5065 - http://flybase.org/reports/FBgn0034145 protein_coding_gene long-chain-fatty-acyl-CoA reductase activity ; GO:0050062 | inferred from sequence or structural similarity with UniProtKB:Q922J9 fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 ether lipid biosynthetic process ; GO:0008611 | inferred from sequence or structural similarity with HGNC:26222 wax biosynthetic process ; GO:0010025 | inferred from sequence or structural similarity with UniProtKB:Q922J9 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with UniProtKB:Q922J9 peroxisomal membrane ; GO:0005778 | inferred from sequence model CG5065 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG5065 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97m3.1, Drer\far1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far1, Mmus\Far2" "Hsap\FAR1, Hsap\FAR2" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0034990 CG11406 - http://flybase.org/reports/FBgn0034990 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" - - CG11406 "IPR025483:Lipase, eukaryotic, IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG11406 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH2, Scer\TGL1, Scer\YEH1" "Cele\lipl-3, Cele\lipl-6, Cele\lipl-2, Cele\lipl-7, Cele\lipl-4, Cele\lipl-1, Cele\lipl-8, Cele\lipl-5" Xtro\lipa "Mmus\Lipo2, Mmus\Lipf, Mmus\Lipa, Mmus\Lipk, Mmus\Lipn, Mmus\Lipo1, Mmus\Lipo4, Mmus\Lipm, Mmus\Lipo3" "Hsap\LIPK, Hsap\LIPF, Hsap\LIPA, Hsap\LIPJ, Hsap\LIPM, Hsap\LIPN" "viable,fertile" FBgn0001813 l(1)nc2 lethal (1) nc2 http://flybase.org/reports/FBgn0001813 - gene - - - "l(1)1625, l(1)nc2" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060800 l(3)S057310 lethal (3) S057310 http://flybase.org/reports/FBgn0060800 gene - - - "0573/10, l(3)S057310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0004546 l(4)102CDq lethal (4) 102CDq http://flybase.org/reports/FBgn0004546 - gene - - - "l(4)CDq, l(4)32, l(4)102CDq" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030181 CG12645 - http://flybase.org/reports/FBgn0030181 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG12645 IPR006629:LPS-induced tumour necrosis factor alpha factor CG12645 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-202h22.9, Drer\cdip1, Drer\litaf, Drer\si:ch211-157c3.4, Drer\si:dkeyp-75b4.8, Drer\si:ch211-202h22.8, Drer\si:ch211-202h22.7" - "Cele\Y40H7A.11, Cele\C08E8.1, Cele\Y37D8A.26, Cele\F16F9.1, Cele\B0348.2, Cele\F36G3.3, Cele\B0348.1, Cele\Y37D8A.6, Cele\Y87G2A.18, Cele\Y37D8A.8, Cele\Y22D7AL.15, Cele\Y87G2A.19" Xtro\litaf "Mmus\Cdip1, Mmus\Litaf" "Hsap\CDIP1, Hsap\LITAF" lethal FBgn0083038 snoRNA:Psi18S-525a snoRNA:Psi18S-525a http://flybase.org/reports/FBgn0083038 snoRNA_gene - - - "snoRNA:Psi18S-525a, psi18S-525a, Psi 18S-525a, CR34570" - CR34570 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039137 CG13604 - http://flybase.org/reports/FBgn0039137 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from sequence or structural similarity with SGD:S000005636 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with SGD:S000005636 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:12462 "UBASH3A, CG13604" "IPR015940:Ubiquitin-associated domain, IPR001452:SH3 domain, IPR009060:UBA-like, IPR013078:Histidine phosphatase superfamily, clade-1, IPR029033:Histidine phosphatase superfamily" CG13604 11-Aug-17 DroID_v2017_08 "Drer\ubash3bb, Drer\ubash3ba" "Scer\TFC7, Scer\YNL108C" "Cele\F53B6.7, Cele\F09C12.8, Cele\T07F12.1, Cele\C52E4.7, Cele\F55A11.11" Xtro\ubash3b "Mmus\Ubash3a, Mmus\Ubash3b" "Hsap\UBASH3A, Hsap\UBASH3B" "viable,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0000680 flrdC flight reduced C http://flybase.org/reports/FBgn0000680 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdC - - 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,jumping defective,visible,flight defective" wing FBgn0083141 Spn28B Serpin 28B http://flybase.org/reports/FBgn0083141 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG6717, Spn28B, Spn7" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG6717 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-416d2.3, Drer\serpind1, Drer\serpine3, Drer\serpinh1a, Drer\serpinc1, Drer\serpina10a, Drer\agt, Drer\si:ch211-186e20.7, Drer\zgc:173729, Drer\serpina1l, Drer\serpine1, Drer\serpina7, Drer\serpine2, Drer\serpinb14, Drer\zgc:174259, Drer\serpinb1l4, Drer\serpinb1l1, Drer\serpinb1, Drer\serpinb1l3, Drer\serpinb1l2, Drer\serpinh1b, Drer\serpini1, Drer\serpinh2" - "Cele\srp-8, Cele\srp-3, Cele\srp-1, Cele\srp-2, Cele\srp-7, Cele\srp-6" "Xtro\serpinb6, Xtro\serpinb4, Xtro\serpinc1, Xtro\serpini1, Xtro\serpini2, Xtro\serpind1, Xtro\serpine2, Xtro\serpina3m, Xtro\serpina10, Xtro\serpinh1, Xtro\serpinb11, Xtro\serpina3k, Xtro\serpinb5, Xtro\serpina1, Xtro\serpinb1, Xtro\serpina3, Xtro\serpine1" "Mmus\Gm11397, Mmus\Serpina5, Mmus\Serpinc1, Mmus\Serpinb9c, Mmus\Serpinb3c, Mmus\Serpinb9b, Mmus\Serpina9, Mmus\Serpinb6d, Mmus\Serpina3j, Mmus\Serpinb9, Mmus\Serpinb9g, Mmus\Serpinb6b, Mmus\Serpinb1c, Mmus\Serpina7, Mmus\Serpinb8, Mmus\Serpina3c, Mmus\Serpinb9e, Mmus\Serpine3, Mmus\Serpinb5, Mmus\Serpinb6c, Mmus\Serpinb9f, Mmus\Serpina1a, Mmus\Serpini2, Mmus\Serpinb3d, Mmus\Serpind1, Mmus\Serpina3f, Mmus\Serpinb3b, Mmus\Serpina1d, Mmus\Serpina1f, Mmus\Serpinb9d, Mmus\Serpinb13, Mmus\Serpina3i, Mmus\Serpinb6e, Mmus\Serpina12, Mmus\Serpinb1a, Mmus\Serpinb11, Mmus\Serpina3a, Mmus\Serpina1e, Mmus\Serpinh1, Mmus\Serpinb10, Mmus\Serpinb7, Mmus\Serpina11, Mmus\Serpine1, Mmus\Serpinb2, Mmus\Serpina3k, Mmus\Serpine2, Mmus\Serpinb3a, Mmus\Serpina6, Mmus\Serpini1, Mmus\Serpinb12, Mmus\Serpina10, Mmus\Serpina3n, Mmus\Serping1, Mmus\Serpinb6a, Mmus\Serpina3g, Mmus\Serpinb1b, Mmus\Serpina16, Mmus\Serpina1c" "Hsap\SERPINB9, Hsap\SERPINA10, Hsap\SERPINB11, Hsap\SERPINA9, Hsap\SERPINB6, Hsap\SERPINB12, Hsap\SERPINE2, Hsap\SERPINI1, Hsap\SERPINB8, Hsap\SERPINA11, Hsap\SERPINH1, Hsap\SERPINB10, Hsap\SERPINC1, Hsap\HMSD, Hsap\SERPINA3, Hsap\SERPING1, Hsap\SERPINA12, Hsap\SERPIND1, Hsap\SERPINE1, Hsap\SERPINB1, Hsap\SERPINA1, Hsap\SERPINB2, Hsap\SERPINA7, Hsap\SERPINB4, Hsap\SERPINB3, Hsap\SERPINA2, Hsap\SERPINA4, Hsap\SERPINE3, Hsap\SERPINI2, Hsap\SERPINB7, Hsap\SERPINB13, Hsap\SERPINA6, Hsap\SERPINA5, Hsap\SERPINB5" viable FBgn0065440 l(2)SH1459 lethal (2) SH1459 http://flybase.org/reports/FBgn0065440 gene - - - "l(2)SH1459, l(2)SH2 1459" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016634 E(gl)3B Enhancer of glass 3B http://flybase.org/reports/FBgn0016634 - gene - - - E(gl)3B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" rhabdomere FBgn0002857 Mst47A Male-specific RNA 47A http://flybase.org/reports/FBgn0002857 - gene - - - "mst-325, mst325, Mst47A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051391 CG31391 - http://flybase.org/reports/FBgn0051391 protein_coding_gene phosphatase binding ; GO:0019902 | inferred from electronic annotation with InterPro:IPR026142 negative regulation of phosphatase activity ; GO:0010923 | inferred from electronic annotation with InterPro:IPR026142 - "CG6471, BcDNA:AT04406, CG31391" IPR026142:Protein phosphatase 1 regulatory subunit 36 CG31391 11-Aug-17 DroID_v2017_08 Drer\ppp1r36 - - - Mmus\Ppp1r36 Hsap\PPP1R36 "viable,fertile" FBgn0051616 His-Psi:CR31616 His-Psi:CR31616 http://flybase.org/reports/FBgn0051616 pseudogene_attribute - - - "bs28b08.y1, CR31616, His-Psi:CR31616" - CR31616 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267178 CR45618 - http://flybase.org/reports/FBgn0267178 non_protein_coding_gene - - - CR45618 - CR45618 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065852 l(2)SH0303 lethal (2) SH0303 http://flybase.org/reports/FBgn0065852 gene - - - "l(2)SH0303, l(2)SH2 0303" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005308 ms(1)RD7 male sterile (1) RD7 http://flybase.org/reports/FBgn0005308 - gene - - - "ms(1)RD-7, ms(1)RD7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,meiotic cell cycle defective" "meiosis I & spindle | male,meiosis II & spindle | male,meiotic anaphase I & nuclear chromosome | male,spermatid & nucleus,meiotic cell cycle & centriole | male,spermatid,meiosis & nuclear chromosome" FBgn0085385 bma black match http://flybase.org/reports/FBgn0085385 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719 molecular_function ; GO:0003674 | no biological data available protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719 detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG12524, CG14163, CG34356, bma" "IPR011009:Protein kinase-like domain, IPR000719:Protein kinase domain, IPR016024:Armadillo-type fold" CG34356 11-Aug-17 DroID_v2017_08 Drer\si:ch211-244b2.1 Scer\SCY1 Cele\ZC581.9 Xtro\scyl2 Mmus\Scyl2 Hsap\SCYL2 "visible,body color defective,partially lethal - majority die,some die during pupal stage,viable" mesothoracic tergum FBgn0060481 l(3)S110915 lethal (3) S110915 http://flybase.org/reports/FBgn0060481 gene - - - "1109/15, l(3)S110915" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0046677 anon-38C.18 anon-38C.18 http://flybase.org/reports/FBgn0046677 gene - - - "38C.18, anon-38C.18" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037915 CG6790 - http://flybase.org/reports/FBgn0037915 protein_coding_gene mannose-ethanolamine phosphotransferase activity ; GO:0051377 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 "NEST:bs22e02, anon-WO0140519.186, CG6790" "IPR007070:GPI ethanolamine phosphate transferase 1, IPR017850:Alkaline-phosphatase-like, core domain, IPR017852:GPI ethanolamine phosphate transferase 1, C-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG6790 11-Aug-17 DroID_v2017_08 Drer\pign Scer\MCD4 Cele\Y54E10BR.1 - Mmus\Pign Hsap\PIGN viable FBgn0037880 CG17726 - http://flybase.org/reports/FBgn0037880 protein_coding_gene - mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from sequence or structural similarity with UniProtKB:Q7L592 mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from biological aspect of ancestor with PANTHER:PTN000248258 ATP metabolic process ; GO:0046034 | inferred from biological aspect of ancestor with PANTHER:PTN000248248 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q7L592 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000248258 CG17726 "IPR003788:Protein arginine methyltransferase NDUFAF7, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG17726 11-Aug-17 DroID_v2017_08 Drer\ndufaf7 - Cele\ZK1128.1 Xtro\ndufaf7 Mmus\Ndufaf7 Hsap\NDUFAF7 viable FBgn0020220 Crp22 Chromatin decondensation protein 22 http://flybase.org/reports/FBgn0020220 - gene - - - "p22, Crp22" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002205 l(3)67BDc lethal (3) 67BDc http://flybase.org/reports/FBgn0002205 - gene - - - l(3)67BDc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal" FBgn0060706 l(3)S070717 lethal (3) S070717 http://flybase.org/reports/FBgn0060706 gene - - - "0707/17, l(3)S070717" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0038158 CG14370 - http://flybase.org/reports/FBgn0038158 protein_coding_gene - - - CG14370 - CG14370 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034513 CG13423 - http://flybase.org/reports/FBgn0034513 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from electronic annotation with InterPro:IPR004134 cysteine-type peptidase activity ; GO:0008234 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR004134 response to toxic substance ; GO:0009636 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 homocysteine catabolic process ; GO:0043418 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 CG13423 "IPR004134:Peptidase C1B, bleomycin hydrolase" CG13423 11-Aug-17 DroID_v2017_08 Drer\blmh Scer\LAP3 - Xtro\blmh Mmus\Blmh Hsap\BLMH viable FBgn0029822 CG12236 - http://flybase.org/reports/FBgn0029822 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 CG12236 "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR011989:Armadillo-like helical, IPR013087:Zinc finger C2H2-type" CG12236 11-Aug-17 DroID_v2017_08 Drer\zbtb7a "Scer\YPR015C, Scer\CMR3" - - "Mmus\Nacc1, Mmus\Zbtb49" "Hsap\BACH1, Hsap\BACH2, Hsap\NACC1, Hsap\ZBTB43, Hsap\ZBTB9" FBgn0261245 sing singles bar http://flybase.org/reports/FBgn0261245 protein_coding_gene molecular_function ; GO:0003674 | no biological data available adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001103553 integral component of membrane ; GO:0016021 | inferred from sequence model "sing, singles-bar, CG13011" IPR008253:Marvel domain CG13011 11-Aug-17 DroID_v2017_08 "Drer\zgc:136605, Drer\cmtm7, Drer\plp2, Drer\cmtm4, Drer\cmtm6, Drer\cmtm3" - "Cele\drr-1, Cele\K09G1.1" - "Mmus\Cmtm4, Mmus\Cmtm3, Mmus\Cmtm5, Mmus\Plp2, Mmus\Cmtm7, Mmus\Cklf, Mmus\Cmtm2a, Mmus\Cmtm1, Mmus\Cmtm2b, Mmus\Cmtm6" "Hsap\CMTM2, Hsap\CMTM1, Hsap\CMTM7, Hsap\CMTM3, Hsap\CKLF, Hsap\CMTM5, Hsap\CMTM6, Hsap\PLP2, Hsap\CMTM4" FBgn0037747 CG8481 - http://flybase.org/reports/FBgn0037747 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 - - CG8481 "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG8481 11-Aug-17 DroID_v2017_08 Drer\LOC101886319 - Cele\C56G2.15 Xtro\nat6 Mmus\Nat6 Hsap\NAT6 "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0062698 EP1139 EP1139 http://flybase.org/reports/FBgn0062698 gene - - - "EP(2)1139, EP1139" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067876 Mod(Prat:bw)3-10 Mod(Prat:bw)3-10 http://flybase.org/reports/FBgn0067876 gene - - - "Mod-3-10, Mod(Prat:bw)3-10" - - 11-Aug-17 DroID_v2017_08 - - - - - - suppressor of variegation FBgn0038833 CG15696 - http://flybase.org/reports/FBgn0038833 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - CG15696 "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site" CG15696 11-Aug-17 DroID_v2017_08 "Drer\msx2a, Drer\msx1a, Drer\msx2b, Drer\msx3, Drer\hoxb1a, Drer\msx1b" - "Cele\pha-2, Cele\vab-15, Cele\ceh-13, Cele\pax-1" "Xtro\gsx1, Xtro\msx2, Xtro\msx1" "Mmus\Msx1, Mmus\Msx3, Mmus\Msx2, Mmus\Dlx2" "Hsap\MSX1, Hsap\DLX2, Hsap\HOXB13, Hsap\MSX2" viable FBgn0024359 ES1-1 Enhancer of GMR-sina 1-1 http://flybase.org/reports/FBgn0024359 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ES1-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye photoreceptor cell,somatic clone,ommatidium" FBgn0050436 CG30436 - http://flybase.org/reports/FBgn0050436 protein_coding_gene - - - CG30436 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250833 CG34461 - http://flybase.org/reports/FBgn0250833 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with UniProtKB:P11734 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG34461, anon-SAGE:Wang-027, Cpr66Ca, CG7072, DmelCpr66Ca" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG34461 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable DRSC10767 E 0.104629907 0.610326479 2.001534317 0.405183842 -0.419032544 -1.26810773 FBgn0265107 CR44209 - http://flybase.org/reports/FBgn0265107 non_protein_coding_gene - - - CR44209 - CR44209 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005121 l(1)S9 lethal (1) S9 http://flybase.org/reports/FBgn0005121 - gene - - - l(1)S9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic" "embryo,anterior,cleavage nucleus" FBgn0264567 CR43939 - http://flybase.org/reports/FBgn0264567 non_protein_coding_gene - - - CR43939 - CR43939 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005529 l(2)52ACf lethal (2) 52ACf http://flybase.org/reports/FBgn0005529 - gene - - - l(2)52ACf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264863 CR44054 - http://flybase.org/reports/FBgn0264863 non_protein_coding_gene - - - CR44054 - CR44054 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061163 l(1)6C-157 lethal (1) 6C-157 http://flybase.org/reports/FBgn0061163 gene - - - "6C-157, l(1)6C-157" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033258 CG8712 - http://flybase.org/reports/FBgn0033258 protein_coding_gene - - - CG8712 - CG8712 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0002314 l(3)85Ae lethal (3) 85Ae http://flybase.org/reports/FBgn0002314 - gene - - - "L5, l(3)85Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037942 CG14721 - http://flybase.org/reports/FBgn0037942 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR007371 thiamine binding ; GO:0030975 | inferred from electronic annotation with InterPro:IPR007373 thiamine diphosphokinase activity ; GO:0004788 | inferred from biological aspect of ancestor with PANTHER:PTN000341466 thiamine metabolic process ; GO:0006772 | inferred from electronic annotation with InterPro:IPR006282 thiamine diphosphate biosynthetic process ; GO:0009229 | inferred from biological aspect of ancestor with PANTHER:PTN000341466 - CG14721 "IPR006282:Thiamin pyrophosphokinase, IPR007371:Thiamin pyrophosphokinase, catalytic domain, IPR007373:Thiamin pyrophosphokinase, vitamin B1-binding domain" CG14721 11-Aug-17 DroID_v2017_08 Drer\tpk1 Scer\THI80 Cele\tpk-1 Xtro\tpk1 Mmus\Tpk1 Hsap\TPK1 "viable,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0266169 CR44875 - http://flybase.org/reports/FBgn0266169 non_protein_coding_gene - - - CR44875 - CR44875 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025754 l(3)93DFh lethal (3) 93DFh http://flybase.org/reports/FBgn0025754 - gene - - - l(3)93DFh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052792 ppk8 pickpocket 8 http://flybase.org/reports/FBgn0052792 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG32792, ppk29, ppk8" IPR001873:Epithelial sodium channel CG32792 11-Aug-17 DroID_v2017_08 "Drer\asic4b, Drer\asic1b, Drer\asic1a, Drer\asic2, Drer\asic4a, Drer\asic1c" - "Cele\delm-2, Cele\acd-4, Cele\acd-1, Cele\del-8, Cele\acd-3, Cele\acd-2, Cele\acd-5, Cele\delm-1, Cele\asic-1, Cele\flr-1, Cele\del-7, Cele\del-6" "Xtro\asic1, Xtro\asic4, Xtro\scnn1a, Xtro\asic5, Xtro\scnn1g, Xtro\scnn1b, Xtro\scnn1d" "Mmus\Asic4, Mmus\Asic1, Mmus\Asic3, Mmus\Asic5, Mmus\Scnn1b, Mmus\Scnn1g, Mmus\Asic2, Mmus\Scnn1a" "Hsap\ASIC1, Hsap\SCNN1G, Hsap\ASIC5, Hsap\ASIC2, Hsap\SCNN1D, Hsap\SCNN1A, Hsap\ASIC3, Hsap\ASIC4, Hsap\SCNN1B" "viable,touch sensitivity defective,fertile" FBgn0002488 l(3)SG48 lethal (3) SG48 http://flybase.org/reports/FBgn0002488 - gene - - - l(3)SG48 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0060692 l(3)S073403 lethal (3) S073403 http://flybase.org/reports/FBgn0060692 gene - - - "0734/03, l(3)S073403" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0037581 CG7352 - http://flybase.org/reports/FBgn0037581 protein_coding_gene - - - CG7352 IPR026504:Meiosis-specific nuclear structural protein 1 CG7352 11-Aug-17 DroID_v2017_08 "Drer\cfap53, Drer\mns1" - - - Mmus\Mns1 Hsap\MNS1 viable FBgn0041753 hedera hedera http://flybase.org/reports/FBgn0041753 gene - - - hedera - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0085517 CG40793 - http://flybase.org/reports/FBgn0085517 protein_coding_gene - - - CG40793 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265927 CR44716 - http://flybase.org/reports/FBgn0265927 non_protein_coding_gene - - - "CR44716, lincRNA.504" - CR44716 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024704 anon-86Ca anon-86Ca http://flybase.org/reports/FBgn0024704 - gene - - - "Group 1, anon-86Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041610 abd-A::Ubx abd-A::Ubx http://flybase.org/reports/FBgn0041610 engineered_fusion_gene - - - abd-A::Ubx - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053203 CG33203 - http://flybase.org/reports/FBgn0053203 protein_coding_gene receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000465443 lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004254 "CG14525, CG14524, CG14522, CG31046, CG33203" IPR004254:AdipoR/Haemolysin-III-related CG33203 11-Aug-17 DroID_v2017_08 "Drer\paqr7b, Drer\paqr7a, Drer\paqr4b, Drer\paqr5b, Drer\paqr3a, Drer\paqr8, Drer\adipor1b, Drer\paqr6, Drer\adipor2, Drer\paqr3b, Drer\paqr4a, Drer\paqr5a" "Scer\IZH3, Scer\IZH4, Scer\IZH1, Scer\IZH2" - "Xtro\adipor1, Xtro\paqr6, Xtro\paqr3, Xtro\paqr4, Xtro\paqr5, Xtro\paqr8" "Mmus\Paqr3, Mmus\Paqr7, Mmus\LOC101055651, Mmus\Adipor2, Mmus\Paqr4, Mmus\Paqr9, Mmus\Paqr8, Mmus\Paqr6, Mmus\Paqr5, Mmus\Adipor1" "Hsap\PAQR3, Hsap\ADIPOR2, Hsap\PAQR4, Hsap\PAQR8, Hsap\PAQR5, Hsap\PAQR9, Hsap\ADIPOR1, Hsap\PAQR7, Hsap\PAQR6" "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0037953 CG14727 - http://flybase.org/reports/FBgn0037953 protein_coding_gene - - - CG14727 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259213 CG42313 - http://flybase.org/reports/FBgn0259213 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42313, BG:SD01219.3, CT35222, BG:DS03144.1, BG:DS01219.3, CG15275, CG15276, CG33515, CG15277, cg15277, 42313" "IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype, IPR003598:Immunoglobulin subtype 2" CG42313 11-Aug-17 DroID_v2017_08 Drer\hmcn2 - - - "Mmus\Siglec1, Mmus\Siglece" "Hsap\MERTK, Hsap\SIGLEC7, Hsap\PSG1, Hsap\SIGLEC6, Hsap\SIGLEC9, Hsap\SIGLEC8, Hsap\SIGLEC12" DRSC02480 E 0.750418526 0.380029236 1.165203855 2.366792169 -0.257905605 0.812918767 FBgn0262812 CG43183 - http://flybase.org/reports/FBgn0262812 protein_coding_gene - - - "CG43183, DMG4-MB6.chr2R.8.009, DMG4-MB6.chr2R.8.009-MIP07212, lincRNA.270, TCONS_00091845" - CG43183 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262433 mir-210 mir-210 stem loop http://flybase.org/reports/FBgn0262433 miRNA_gene - - - "dme-mir-210, miR-210, mir-210, MIR-210, CR42991, CR33578, dme-miR-210" - CR42991 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,partially lethal - majority die" "wing,wing vein,wing margin,1st posterior cell" FBgn0029807 CG3108 - http://flybase.org/reports/FBgn0029807 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG3108 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG3108 11-Aug-17 DroID_v2017_08 "Drer\cpa2, Drer\cpo, Drer\cpa4, Drer\cpb1, Drer\cpa5, Drer\cpb2, Drer\cpa1, Drer\cpa6" "Scer\ECM14, Scer\YFR016C" "Cele\T06A4.1, Cele\W01A8.6, Cele\ZC434.9, Cele\Y47G6A.19, Cele\Y18H1A.9, Cele\F02D8.4, Cele\T06A4.3, Cele\Y59C2A.1, Cele\T24E12.10, Cele\suro-1" "Xtro\cpo, Xtro\cpb1, Xtro\cpa3, Xtro\LOC100487462, Xtro\cpa1, Xtro\cpb2" "Mmus\Cpa6, Mmus\Cpa5, Mmus\Cpa2, Mmus\Cpb2, Mmus\Cpa4, Mmus\Cpa3, Mmus\Cpb1, Mmus\Cpa1" "Hsap\CPA3, Hsap\CPB1, Hsap\CPO, Hsap\CPA6, Hsap\CPA1, Hsap\CPA4, Hsap\AKAP12, Hsap\CPB2, Hsap\CPA5, Hsap\CPA2" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0036849 CG14079 - http://flybase.org/reports/FBgn0036849 protein_coding_gene - - - CG14079 "IPR032732:Spermatogenesis-associated protein 6, N-terminal" CG14079 11-Aug-17 DroID_v2017_08 "Drer\spata6l, Drer\spata6" - - - "Mmus\4430402I18Rik, Mmus\Spata6" "Hsap\SPATA6, Hsap\SPATA6L" viable FBgn0003224 reduced-eyes reduced eyes http://flybase.org/reports/FBgn0003224 - gene - - - "reduced-eyes, re" - - 11-Aug-17 DroID_v2017_08 - - - - - - sterile ommatidium FBgn0032428 CG6405 - http://flybase.org/reports/FBgn0032428 protein_coding_gene signal transducer activity ; GO:0004871 | inferred from sequence or structural similarity with SGD:S000003065 negative regulation of protein secretion ; GO:0050709 | inferred from sequence or structural similarity with HGNC:17499 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:17499 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:17499 CG6405 IPR009602:FAM92 protein CG6405 11-Aug-17 DroID_v2017_08 Drer\fam92a1 - - "Xtro\fam92a1, Xtro\fam92b" "Mmus\Fam92b, Mmus\Fam92a" "Hsap\FAM92A, Hsap\FAM92B" viable embryonic/larval salivary gland FBgn0039261 CG6422 - http://flybase.org/reports/FBgn0039261 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR007275 - cytoplasm ; GO:0005737 | inferred from direct assay CG6422 IPR007275:YTH domain CG6422 11-Aug-17 DroID_v2017_08 "Drer\ythdf1, Drer\ythdf3, Drer\ythdf2" Scer\PHO92 - "Xtro\ythdf3, Xtro\ythdf2, Xtro\ythdf1" "Mmus\Ythdc1, Mmus\Ythdf3, Mmus\Ythdf1, Mmus\Ythdf2" "Hsap\YTHDF2, Hsap\YTHDC1, Hsap\YTHDF3, Hsap\YTHDF1" viable FBgn0261261 plx pollux http://flybase.org/reports/FBgn0261261 protein_coding_gene integrin binding ; GO:0005178 | inferred from direct assay Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab19 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 cell adhesion mediated by integrin ; GO:0033627 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay "Plx, plx, CG1093, CG42612, CG14674, CG34122" "IPR000195:Rab-GTPase-TBC domain, IPR006020:PTB/PI domain, IPR011993:PH domain-like, IPR021785:Domain of unknown function DUF3350" CG42612 11-Aug-17 DroID_v2017_08 "Drer\tbc1d4, Drer\tbc1d1, Drer\evi5b, Drer\si:ch211-239f4.1, Drer\adprhl1" "Scer\GYP5, Scer\GYL1" Cele\eat-17 "Xtro\tbc1d4, Xtro\tbc1d1, Xtro\evi5l, Xtro\evi5" "Mmus\Adprhl1, Mmus\Tbc1d4, Mmus\Evi5, Mmus\Evi5l, Mmus\Tbc1d1" "Hsap\ADPRHL1, Hsap\TBC1D1, Hsap\TBC1D4, Hsap\EVI5, Hsap\SGSM1, Hsap\EVI5L" " adult stage , embryonic stage -- adult stage " organism

" embryonic stage | stage >=15 , embryonic stage | stage >=12 , embryonic stage , embryonic stage | stage 13-17 , embryonic stage | stage 5 , embryonic stage | stage >=13 " " embryonic/larval trachea

, neuron

, endocuticle

, neuron

, cell body

,

, longitudinal connective

" FBgn0038189 Art6 Arginine methyltransferase 6 http://flybase.org/reports/FBgn0038189 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR025799 peptidyl-arginine methylation ; GO:0018216 | inferred from sequence or structural similarity with HGNC:5187 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:5187 "DART6, CG9927, Art6" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR025799:Protein arginine N-methyltransferase" CG9927 11-Aug-17 DroID_v2017_08 "Drer\LOC556054, Drer\prmt2, Drer\prmt8b, Drer\prmt3, Drer\prmt6, Drer\prmt1" Scer\HMT1 - "Xtro\prmt8, Xtro\prmt1, Xtro\prmt3, Xtro\prmt6" "Mmus\Prmt6, Mmus\Prmt3, Mmus\Prmt8, Mmus\Prmt1, Mmus\Prmt2" "Hsap\PRMT6, Hsap\PRMT1, Hsap\PRMT8, Hsap\PRMT2, Hsap\PRMT3" viable FBgn0261844 pre-mod(mdg4)-V - http://flybase.org/reports/FBgn0261844 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-V, CG42776, RV" "IPR007588:Zinc finger, FLYWCH-type" CG42776 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038810 Srp72 Signal recognition particle protein 72 http://flybase.org/reports/FBgn0038810 protein_coding_gene 7S RNA binding ; GO:0008312 | inferred from electronic annotation with InterPro:IPR013699 "SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616 | inferred from biological aspect of ancestor with PANTHER:PTN000363482 dsRNA transport ; GO:0033227 | inferred from mutant phenotype" "signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from biological aspect of ancestor with PANTHER:PTN000363482" "CG5434, Srp72" "IPR011990:Tetratricopeptide-like helical domain, IPR013699:Signal recognition particle, SRP72 subunit, RNA-binding, IPR019734:Tetratricopeptide repeat, IPR026270:Signal recognition particle, SRP72 subunit, IPR031545:Putative TPR-like repeat" CG5434 11-Aug-17 DroID_v2017_08 Drer\srp72 Scer\SRP72 Cele\srpa-72 Xtro\srp72 "Mmus\Srp72, Mmus\Ift88" Hsap\SRP72 lethal FBgn0030027 CG1632 - http://flybase.org/reports/FBgn0030027 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "SPH198, CG1632" "IPR000082:SEA domain, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR017343:Uncharacterised conserved protein UCP037987, IPR020067:Frizzled domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG1632 11-Aug-17 DroID_v2017_08 "Drer\si:cabz01033205.3, Drer\sfrp5, Drer\fzd10, Drer\fzd9b, Drer\smo, Drer\fzd9a, Drer\st14b, Drer\fzd5, Drer\sfrp2l, Drer\corin, Drer\fzd3a, Drer\fzd7b, Drer\sfrp1b, Drer\fzd3b, Drer\fzd8a, Drer\st14a, Drer\tmprss15, Drer\fzd8b, Drer\fzd7a, Drer\LOC101884738, Drer\sfrp2, Drer\sfrp1a, Drer\frzb, Drer\zmp:0000001114, Drer\szl, Drer\fzd2" - - "Xtro\corin, Xtro\fzd10, Xtro\fzd9, Xtro\frzb2, Xtro\sfrpx, Xtro\fzd5, Xtro\frzb, Xtro\sfrp2, Xtro\sfrp5, Xtro\smo, Xtro\fzd3, Xtro\col18a1, Xtro\sfrp1, Xtro\szl, Xtro\mfrp, Xtro\fzd7, Xtro\fzd6, Xtro\fzd2, Xtro\fzd8, Xtro\fzd4" "Mmus\Fzd7, Mmus\Fzd8, Mmus\Smo, Mmus\Fzd4, Mmus\Fzd10, Mmus\Fzd6, Mmus\Fzd3, Mmus\Fzd2, Mmus\Fzd1, Mmus\Sfrp2, Mmus\Sfrp5, Mmus\Mfrp, Mmus\Sfrp1, Mmus\Sfrp4, Mmus\Corin, Mmus\Frzb, Mmus\Fzd5, Mmus\Fzd9" "Hsap\FZD4, Hsap\SFRP5, Hsap\SFRP1, Hsap\FZD3, Hsap\SFRP4, Hsap\FZD9, Hsap\FZD1, Hsap\SMO, Hsap\MFRP, Hsap\FZD2, Hsap\CORIN, Hsap\TMPRSS13, Hsap\FZD8, Hsap\FZD10, Hsap\FZD5, Hsap\SFRP2, Hsap\FZD7, Hsap\FRZB, Hsap\FZD6, Hsap\TMPRSS3" viable FBgn0035689 CG7376 - http://flybase.org/reports/FBgn0035689 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:19336 zinc ion binding ; GO:0008270 | inferred from sequence model" protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:19336 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG7376, SHPRH" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR001841:Zinc finger, RING-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR013026:Tetratricopeptide repeat-containing domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR017907:Zinc finger, RING-type, conserved site, IPR019734:Tetratricopeptide repeat, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7376 11-Aug-17 DroID_v2017_08 Drer\shprh Scer\IRC20 "Cele\T05A12.4, Cele\T22D1.6" Xtro\shprh Mmus\Shprh Hsap\SHPRH "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0028518 CG18480 - http://flybase.org/reports/FBgn0028518 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CT42128, BG:DS07108.4, BcDNA:LP11031, CG18480" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG18480 11-Aug-17 DroID_v2017_08 "Drer\zgc:153913, Drer\igfals, Drer\si:ch211-237i5.4, Drer\lrit3a, Drer\slitrk4, Drer\lgi1a, Drer\lrtm2a, Drer\rtn4r, Drer\lrrc38b" - Cele\iglr-1 "Xtro\lingo2, Xtro\lrrc52, Xtro\rtn4r, Xtro\LOC100488256, Xtro\lgi1, Xtro\islr2, Xtro\lrrc15" "Mmus\Igfals, Mmus\Lrtm1, Mmus\Lrrc55, Mmus\Lrrc15, Mmus\Lgi1, Mmus\Lrrc26, Mmus\Lrrc52, Mmus\Aspn, Mmus\Lrtm2" "Hsap\LRTM1, Hsap\LRRC55, Hsap\LRRC15, Hsap\LGI1, Hsap\LRRC52, Hsap\LRRC38, Hsap\CPN2, Hsap\LRRC24, Hsap\LRTM2, Hsap\RTN4RL2, Hsap\IGFALS, Hsap\LRRC26, Hsap\RTN4R" "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage" trichogen cell FBgn0035335 mRpL23 mitochondrial ribosomal protein L23 http://flybase.org/reports/FBgn0035335 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000248673 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049646 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049646 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049646 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q16540 "L23, CG1320, BcDNA:RE49852, mRpL23" "IPR012678:Ribosomal protein L23/L15e core domain, IPR013025:Ribosomal protein L25/L23" CG1320 11-Aug-17 DroID_v2017_08 Drer\mrpl23 Scer\MRP20 Cele\mrpl-23 Xtro\mrpl23 Mmus\Mrpl23 "Hsap\MRPL23, Hsap\LOC107987373" "viable,visible" trichogen cell FBgn0260089 2L1693 - http://flybase.org/reports/FBgn0260089 gene - - - 2L1693 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0038931 CG13407 - http://flybase.org/reports/FBgn0038931 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13407 - CG13407 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0011885 tRNA:Ile-AAT-1-7 transfer RNA:Isoleucine-AAT 1-7 http://flybase.org/reports/FBgn0011885 "FBgn0003788, FBgn0050247, FBgn0060196" tRNA_gene AUU codon-amino acid adaptor activity ; GO:0033433 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033433 cytosol ; GO:0005829 | inferred by curator from GO:0033433 "CR30247, ile-e, AE002787.trna40-IleAAT, tRNA:I:AAT:AE002787-f, tRNA:ile:49Fe, tRNA[Ile], chr2R.trna22-IleAAT, tRNA-Ile[AAU], tRNA-Ile-AAT-1-7, tRNA:Ile-AAT-1-7, tRNA:I:49Fe, AUU" - CR30247 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060879 l(3)S045311 lethal (3) S045311 http://flybase.org/reports/FBgn0060879 gene - - - "0453/11, l(3)S045311" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0082639 R705.1 R705.1 http://flybase.org/reports/FBgn0082639 gene - - - R705.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - crystal cell FBgn0031942 CG7203 - http://flybase.org/reports/FBgn0031942 protein_coding_gene - - - CG7203 IPR031874:Adult cuticle protein 1 CG7203 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0029785 RpL35 Ribosomal protein L35 http://flybase.org/reports/FBgn0029785 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000356124 "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001854, InterPro:IPR018254 cytoplasmic translation ; GO:0002181 | traceable author statement maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000463 | inferred from biological aspect of ancestor with PANTHER:PTN000356124 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 centrosome duplication ; GO:0051298 | inferred from mutant phenotype" ribosome ; GO:0005840 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "anon-EST:fe1C12, anon-EST:Posey157, BcDNA:RE09547, CG4111, RpL35, RpL35e, Rp L35" "IPR018254:Ribosomal protein L29, conserved site, IPR001854:Ribosomal protein L29/L36" CG4111 11-Aug-17 DroID_v2017_08 Drer\rpl35 "Scer\RPL35B, Scer\RPL35A" Cele\rpl-35 Xtro\rpl35 Mmus\Rpl35 Hsap\RPL35 lethal DRSC18347 IEK -2.665714012 -0.782623179 -0.015926833 -2.818422194 -0.019687911 2.960935687 FBgn0261811 pico pico http://flybase.org/reports/FBgn0261811 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000159 regulation of cell size ; GO:0008361 | inferred from mutant phenotype positive regulation of developmental growth ; GO:0048639 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype positive regulation of cell division ; GO:0051781 | inferred from mutant phenotype filopodium tip ; GO:0032433 | colocalizes_with inferred from direct assay "pico, jog, CG11940, Pico, BcDNA:LP01106, Grb10" "IPR029071:Ubiquitin-related domain, IPR000159:Ras-associating (RA) domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG11940 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-253b1.3, Drer\apbb1ip, Drer\grb10a, Drer\raph1b, Drer\grb14, Drer\raph1a, Drer\grb10b" - Cele\mig-10 "Xtro\grb10, Xtro\apbb1ip, Xtro\grb7" "Mmus\Grb10, Mmus\Grb14, Mmus\Raph1, Mmus\Grb7, Mmus\Apbb1ip" "Hsap\APBB1IP, Hsap\RAPH1, Hsap\GRB7, Hsap\GRB10, Hsap\GRB14" FBgn0022330 gtw gtw http://flybase.org/reports/FBgn0022330 - gene - - - gtw - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "ommatidium,lamina" FBgn0016032 lbm late bloomer http://flybase.org/reports/FBgn0016032 - protein_coding_gene - cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 synapse assembly ; GO:0007416 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG2374, lbl, Dm.Tsp42Em, Lbm, lbm, LBM, Ibm" "IPR018499:Tetraspanin/Peripherin, IPR008952:Tetraspanin, EC2 domain" CG2374 11-Aug-17 DroID_v2017_08 Drer\cd63 - "Cele\tsp-14, Cele\tsp-7, Cele\tsp-3, Cele\tsp-1, Cele\tsp-2" Xtro\cd63 Mmus\Cd63 Hsap\CD63 embryonic stage | stage 14 " RP neuron

, U neuron

, VUM neuron

, aCC neuron

" embryonic stage | stage 16 motor neuron

"neuroanatomy defective,viable" "synapse,RP3 motor neuron,RP3 neuron & synapse,growth cone,presynaptic ribbon" FBgn0039594 CG9990 - http://flybase.org/reports/FBgn0039594 protein_coding_gene "ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871" transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR000412 plasma membrane ; GO:0005886 | inferred from direct assay CG9990 "IPR000412:ABC-2 transporter, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG9990 11-Aug-17 DroID_v2017_08 "Drer\abca3b, Drer\abca2, Drer\abca5, Drer\abca12, Drer\abca1a, Drer\abca1b, Drer\abch1" Scer\CAF16 "Cele\abt-5, Cele\abt-6, Cele\ced-7" "Xtro\abca8, Xtro\abca3, Xtro\abca4, Xtro\abca10, Xtro\abca1, Xtro\abcg2, Xtro\abca2, Xtro\abca9" "Mmus\Abca8a, Mmus\Abca17, Mmus\Abca3, Mmus\Abca14, Mmus\Abca2, Mmus\Abca1, Mmus\Abca13, Mmus\Abca5, Mmus\Abca6, Mmus\Abca4, Mmus\Abca12, Mmus\Abca8b, Mmus\Abca9, Mmus\Abca16, Mmus\Abca7, Mmus\Abca15" "Hsap\ABCA7, Hsap\ABCA9, Hsap\ABCA8, Hsap\ABCA2, Hsap\ABCA6, Hsap\ABCA1, Hsap\ABCG2, Hsap\ABCA3, Hsap\ABCA10, Hsap\ABCA5, Hsap\ABCA12, Hsap\ABCA13, Hsap\ABCA4" lethal FBgn0016905 l(3)X1 lethal (3) X1 http://flybase.org/reports/FBgn0016905 - gene - - - "X1, l(3)X1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265449 CR44349 - http://flybase.org/reports/FBgn0265449 non_protein_coding_gene - - - CR44349 - CR44349 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038056 CG5961 - http://flybase.org/reports/FBgn0038056 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG5961, FBXO9" "IPR001810:F-box domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR007330:MIT" CG5961 11-Aug-17 DroID_v2017_08 Drer\fbxo9 Scer\HRT3 - Xtro\fbxo9 Mmus\Fbxo9 Hsap\FBXO9 viable FBgn0029665 CG14270 - http://flybase.org/reports/FBgn0029665 protein_coding_gene - - mitochondrial inner membrane protein insertion complex ; GO:0042721 | inferred from electronic annotation with InterPro:IPR019322 CG14270 IPR019322:Mitochondrial import inner membrane translocase subunit Tim29 CG14270 11-Aug-17 DroID_v2017_08 Drer\zgc:110046 - Cele\R04F11.5 Xtro\c19orf52 Mmus\Timm29 Hsap\TIMM29 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0042711 Hex-t1 Hex-t1 http://flybase.org/reports/FBgn0042711 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001312, InterPro:IPR022672, InterPro:IPR022673 glucose binding ; GO:0005536 | inferred from electronic annotation with InterPro:IPR001312 mannokinase activity ; GO:0019158 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 glucokinase activity ; GO:0004340 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 fructokinase activity ; GO:0008865 | inferred from biological aspect of ancestor with PANTHER:PTN000455350" carbohydrate phosphorylation ; GO:0046835 | inferred from electronic annotation with InterPro:IPR001312 cellular glucose homeostasis ; GO:0001678 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 "HK, CG5443, Hex, DHK-453, CG54430, CG33102, Hex-t1, HEX-t1, Hex-T1" "IPR001312:Hexokinase, IPR022672:Hexokinase, N-terminal, IPR022673:Hexokinase, C-terminal" CG33102 11-Aug-17 DroID_v2017_08 "Drer\hk1, Drer\gck, Drer\hkdc1, Drer\hk2" "Scer\HXK1, Scer\GLK1, Scer\HXK2, Scer\EMI2, Scer\YLR446W" "Cele\hxk-1, Cele\hxk-3, Cele\hxk-2" "Xtro\gck, Xtro\hk2, Xtro\hk1" "Mmus\Hk1, Mmus\Hk3, Mmus\Hk2, Mmus\Gck, Mmus\Hkdc1" "Hsap\GCK, Hsap\HKDC1, Hsap\HK2, Hsap\HK1, Hsap\HK3" viable FBgn0011186 l(1)294-44 lethal (1) 294-44 http://flybase.org/reports/FBgn0011186 FBgn0010200 gene - - - "294-44, l(1)294-44" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053385 5SrRNA:CR33385 5SrRNA:CR33385 http://flybase.org/reports/FBgn0053385 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33385, 5SrRNA:CR33385" - CR33385 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030452 MFS10 Major Facilitator Superfamily Transporter 10 http://flybase.org/reports/FBgn0030452 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "AA202479, CG4330, MFS10" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG4330 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-513e17.1, Drer\slc17a6b, Drer\slc17a5, Drer\slc17a6a, Drer\slc17a9a, Drer\ppt1, Drer\slc17a8, Drer\slc17a7a" "Scer\TNA1, Scer\THI73, Scer\DAL5, Scer\FEN2, Scer\YIL166C" "Cele\cima-1, Cele\Y19D10A.4, Cele\F59A1.13, Cele\Y51B9A.6, Cele\M162.5, Cele\Y19D10A.5, Cele\T27D12.1, Cele\T19D12.9, Cele\F56A4.10, Cele\T22F3.10, Cele\T22F3.7, Cele\D1046.4, Cele\Y4C6B.3, Cele\T22F3.8, Cele\F10C2.7, Cele\C01B4.8, Cele\F41C3.2, Cele\C18H9.5, Cele\F11A5.9, Cele\K11G9.5, Cele\slc-17.8, Cele\F56A4.12, Cele\K08C7.1, Cele\C18D1.2, Cele\R10D12.1, Cele\Y15E3A.4, Cele\slc-17.3, Cele\F44E7.7, Cele\T02B11.6, Cele\slc-17.5, Cele\vglu-3, Cele\C35A5.3, Cele\Y19D10A.8, Cele\vglu-2, Cele\slc-17.9, Cele\slc-17.1, Cele\M117.1, Cele\T28H11.8, Cele\T01H3.3, Cele\W04C9.6, Cele\T19D12.10, Cele\C01B4.7, Cele\Y4C6B.4, Cele\H11E01.2, Cele\C39E9.7, Cele\Y19D10A.11, Cele\slc-17.4, Cele\slc-17.2, Cele\eat-4, Cele\T22F3.11" "Xtro\slc17a7, Xtro\slc17a5" "Mmus\Slc17a2, Mmus\Slc17a8, Mmus\Slc17a5, Mmus\Slc17a7, Mmus\Slc17a1, Mmus\Slc17a4, Mmus\Slc17a3, Mmus\Slc17a6" "Hsap\SLC17A5, Hsap\SLC17A4, Hsap\SLC17A7, Hsap\SLC17A2, Hsap\SLC17A3, Hsap\SLC17A8, Hsap\SLC17A1, Hsap\SLC17A6" "viable,fertile" FBgn0036263 thoc6 thoc6 http://flybase.org/reports/FBgn0036263 protein_coding_gene - mRNA export from nucleus in response to heat stress ; GO:0031990 | inferred by curator from GO:0000347 response to heat ; GO:0009408 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype THO complex ; GO:0000347 | inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:28369 "THOC6, CG5632, thoc6, Thoc6" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat" CG5632 11-Aug-17 DroID_v2017_08 "Drer\thoc6, Drer\tle2" - Cele\gpb-1 Xtro\thoc6 "Mmus\Thoc6, Mmus\Tle2" "Hsap\TLE2, Hsap\THOC6" "viable,fertile" FBgn0263651 CR43642 - http://flybase.org/reports/FBgn0263651 non_protein_coding_gene - - - CR43642 - CR43642 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017440 anon-21Cc anon-21Cc http://flybase.org/reports/FBgn0017440 - gene - - - anon-21Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028600 l(2)W7 lethal (2) W7 http://flybase.org/reports/FBgn0028600 gene - - - "l(2R)W7, l(2)W7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067649 sd-6 sd-6 http://flybase.org/reports/FBgn0067649 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,neurophysiology defective,somatic clone,phototaxis defective" FBgn0005689 Nc18A Neural conserved at 18A http://flybase.org/reports/FBgn0005689 - gene - - - "NC18A, Nc18A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017421 anon-75Ea anon-75Ea http://flybase.org/reports/FBgn0017421 - gene - - - anon-75Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030296 CG15196 - http://flybase.org/reports/FBgn0030296 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15196 - CG15196 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0036979 CG13247 - http://flybase.org/reports/FBgn0036979 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13247 IPR008974:TRAF-like CG13247 11-Aug-17 DroID_v2017_08 - - - - - - DRSC11695 K -0.527541286 -0.020453409 -0.107203607 0.548503251 -2.182188963 -1.418069493 FBgn0277429 l(3)psg24 - http://flybase.org/reports/FBgn0277429 gene - - - "l(3)psg24, psg24" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001274 Is Isis http://flybase.org/reports/FBgn0001274 - gene - - - Is - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023124 anon-10Aj anon-10Aj http://flybase.org/reports/FBgn0023124 - gene - - - "2, anon-10Aj" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041249 Gr22f Gustatory receptor 22f http://flybase.org/reports/FBgn0041249 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr22B1, GR22b1, GR22B.1, 22B.1, CG31932, Gr22f, GR22f" IPR013604:7TM chemoreceptor CG31932 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - "partially lethal - majority die,some die during pupal stage" FBgn0083156 S(smoDN)1378 Suppressor of smoDN 1378 http://flybase.org/reports/FBgn0083156 gene - - - S(smoDN)1378 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023479 teq Tequila http://flybase.org/reports/FBgn0023479 "FBgn0025714, FBgn0026292, FBgn0029083, FBgn0035961, FBgn0035962, FBgn0035963, FBgn0043819" protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001190 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 regulation of insulin-like growth factor receptor signaling pathway ; GO:0043567 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model long-term memory ; GO:0007616 | inferred from mutant phenotype glucose homeostasis ; GO:0042593 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from direct assay" "extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001190, InterPro:IPR017448" "CG18403, CG4948, graal, SP72, CG18153, CK00198, anon-EST:ParkEST161, CG4821, BEST:GH18038, BEST:CK00198, Tequila, Teq, teq" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001190:SRCR domain, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR002557:Chitin binding domain, IPR009003:Peptidase S1, PA clan, IPR017448:SRCR-like domain, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR033116:Serine proteases, trypsin family, serine active site" CG4821 11-Aug-17 DroID_v2017_08 "Drer\prss12, Drer\mst1, Drer\plg, Drer\habp2, Drer\plat, Drer\si:ch211-51a6.2, Drer\hgfb, Drer\f2, Drer\plaub, Drer\hgfa, Drer\plaua, Drer\si:ch73-127m5.1" - "Cele\svh-1, Cele\C39D10.7, Cele\F48E3.8, Cele\R02F2.4, Cele\cbd-1, Cele\C06B8.7" "Xtro\habp2, Xtro\plat, Xtro\hgf, Xtro\f12, Xtro\f2, Xtro\hgfac, Xtro\mst1" "Mmus\Hgfac, Mmus\F12, Mmus\Prss12, Mmus\Plau, Mmus\Mst1, Mmus\Hgf, Mmus\Plg, Mmus\Fbn1, Mmus\Habp2, Mmus\F2, Mmus\Loxl3, Mmus\Plat" "Hsap\F12, Hsap\HGFAC, Hsap\LOXL3, Hsap\PRSS12, Hsap\PLAU, Hsap\PLG, Hsap\PLAT, Hsap\LPA, Hsap\HABP2, Hsap\MST1, Hsap\HGF, Hsap\F2" "viable,fertile,memory defective,feeding behavior defective,RU486 conditional,partially lethal - majority die,some die during pupal stage" FBgn0043990 Su(rst)E122 Su(rst)E122 http://flybase.org/reports/FBgn0043990 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E122, Su(rst)E122" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262695 Su(VGlut)B17 - http://flybase.org/reports/FBgn0262695 gene - - - "Su(VGlut)B17, B17" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005280 M(3)96A Minute (3) 96A http://flybase.org/reports/FBgn0005280 - gene - - - M(3)96A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260996 CG42597 - http://flybase.org/reports/FBgn0260996 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42597 IPR032145:Protein of unknown function DUF4818 CG42597 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034177 AsnRS-m "Asparaginyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0034177 protein_coding_gene "asparagine-tRNA ligase activity ; GO:0004816 | inferred from electronic annotation with InterPro:IPR004522 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004364, InterPro:IPR004522, InterPro:IPR018150 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004365 asparagine-tRNA ligase activity ; GO:0004816 | traceable author statement" asparaginyl-tRNA aminoacylation ; GO:0006421 | inferred from electronic annotation with InterPro:IPR004522 asparaginyl-tRNA aminoacylation ; GO:0006421 | traceable author statement cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004522 mitochondrion ; GO:0005739 | traceable author statement "CG6796, AsnRS-m" "IPR002312:Aspartyl/Asparaginyl-tRNA synthetase, class IIb, IPR004364:Aminoacyl-tRNA synthetase, class II (D/K/N), IPR004365:OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR004522:Asparagine-tRNA ligase, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR012340:Nucleic acid-binding, OB-fold" CG6796 11-Aug-17 DroID_v2017_08 "Drer\nars2, Drer\nars" "Scer\DED81, Scer\SLM5" "Cele\nars-2, Cele\nars-1" Xtro\nars2 "Mmus\Nars, Mmus\Nars2" "Hsap\NARS2, Hsap\NARS" viable FBgn0085626 CG41344 - http://flybase.org/reports/FBgn0085626 protein_coding_gene - - - CG41344 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034154 CG5267 - http://flybase.org/reports/FBgn0034154 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG5267 "IPR002919:Trypsin Inhibitor-like, cysteine rich domain" CG5267 11-Aug-17 DroID_v2017_08 - - "Cele\C53B7.2, Cele\spi-1, Cele\Y26D4A.12, Cele\C25E10.7, Cele\T01D3.3, Cele\C10G8.4, Cele\K07A1.6, Cele\C25E10.8, Cele\F32D8.3, Cele\B0238.12, Cele\swm-1, Cele\F53C11.9" - - - viable FBgn0002599 M(2)39F Minute (2) 39F http://flybase.org/reports/FBgn0002599 - gene - - - "M(2)H, M(2L)H, M(2)S5, M(2)S12, M(2)39F" - - 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,dominant,visible,Minute" macrochaeta FBgn0265061 CR44172 - http://flybase.org/reports/FBgn0265061 non_protein_coding_gene - - - CR44172 - CR44172 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058416 CG40416 - http://flybase.org/reports/FBgn0058416 protein_coding_gene - - - CG40416 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031920 CG6441 - http://flybase.org/reports/FBgn0031920 protein_coding_gene - - - "anon-WO0140519.45, CG6441" "IPR009818:Ataxin-2, C-terminal" CG6441 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028610 l(2)W15 lethal (2) W15 http://flybase.org/reports/FBgn0028610 gene - - - "l(2R)W15, l(2)W15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053403 5SrRNA:CR33403 5SrRNA:CR33403 http://flybase.org/reports/FBgn0053403 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33403, 5SrRNA:CR33403" - CR33403 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040393 CG14265 - http://flybase.org/reports/FBgn0040393 protein_coding_gene - - - "EG:96G10.8, BcDNA:RE43371, CG14265" - CG14265 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0267302 CR45738 - http://flybase.org/reports/FBgn0267302 non_protein_coding_gene - - - CR45738 - CR45738 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053450 5SrRNA:CR33450 5SrRNA:CR33450 http://flybase.org/reports/FBgn0053450 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33450, 5SrRNA:CR33450" - CR33450 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015577 alpha-Est9 alpha-Esterase-9 http://flybase.org/reports/FBgn0015577 - protein_coding_gene cholinesterase activity ; GO:0004104 | inferred from electronic annotation with InterPro:IPR000997 - - "alphaE9, aE9, J, alpha-Est9, CG1128, DmalphaE9, Est9, Dm_3R:18691" "IPR000997:Cholinesterase, IPR002018:Carboxylesterase, type B, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG1128 11-Aug-17 DroID_v2017_08 "Drer\cel.1, Drer\si:ch211-93f2.1, Drer\ces3, Drer\nlgn2a, Drer\nlgn4b, Drer\cell, Drer\nlgn1, Drer\nlgn2b, Drer\nlgn3a, Drer\ces2, Drer\nlgn4a, Drer\nlgn3b" - "Cele\T28C12.5, Cele\T28C12.4, Cele\Y71H2AM.13, Cele\B0238.1" "Xtro\nlgn3, Xtro\ces2, Xtro\LOC100494782, Xtro\cel, Xtro\nlgn4x, Xtro\ces3, Xtro\nlgn2" "Mmus\Nlgn3, Mmus\Ces2c, Mmus\Ces1d, Mmus\Ces2f, Mmus\Nlgn2, Mmus\Nlgn1, Mmus\Ces2h, Mmus\Ces2e, Mmus\Ces1g, Mmus\Cel, Mmus\Ces1e, Mmus\Ces2b, Mmus\Ces1f, Mmus\Ces5a, Mmus\Ces3b, Mmus\Ces1b, Mmus\Ces4a, Mmus\Bche, Mmus\Ces1c, Mmus\Ces2g, Mmus\Ces1h, Mmus\Ces3a, Mmus\Ces2a" "Hsap\CES3, Hsap\NLGN4Y, Hsap\BCHE, Hsap\CES4A, Hsap\NLGN3, Hsap\CES2, Hsap\NLGN1, Hsap\NLGN2, Hsap\CEL, Hsap\NLGN4X, Hsap\CES5A, Hsap\CES1" viable FBgn0259787 l(2)914 - http://flybase.org/reports/FBgn0259787 gene - - - l(2)914 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0264743 CG44001 - http://flybase.org/reports/FBgn0264743 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44001, Dromel_CG31919_FBtr0079006_mORF, CG31919, CG5822" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG44001 11-Aug-17 DroID_v2017_08 "Drer\cdkn2d, Drer\cdkn2a/b, Drer\ankrd39, Drer\cdkn2c" - - Xtro\ankrd39 "Mmus\Cdkn2c, Mmus\Ankrd39, Mmus\Cdkn2b, Mmus\Cdkn2d" "Hsap\CDKN2C, Hsap\CDKN2A, Hsap\ANKRD39, Hsap\ANKRD23, Hsap\ANKRD2, Hsap\ANKRD1, Hsap\CDKN2D, Hsap\CDKN2B" FBgn0042092 CG13773 - http://flybase.org/reports/FBgn0042092 protein_coding_gene RNA polymerase I activity ; GO:0001054 | inferred from sequence or structural similarity with SGD:S000005867 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001398707 transcription from RNA polymerase I promoter ; GO:0006360 | inferred from sequence or structural similarity with SGD:S000005867 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from sequence or structural similarity with SGD:S000005867 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN001398707 "BEST:GH23590, CG13773" - CG13773 11-Aug-17 DroID_v2017_08 Drer\twistnb Scer\RPA43 - Xtro\twistnb Mmus\Twistnb Hsap\TWISTNB "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0058061 CG40061 - http://flybase.org/reports/FBgn0058061 protein_coding_gene - - - CG40061 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016674 Khc::Ggal\MLCK Khc::Ggal\MLCK http://flybase.org/reports/FBgn0016674 - engineered_fusion_gene - - - Khc::Ggal\MLCK - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,neuroanatomy defective" "longitudinal connective,thoracic-abdominal embryonic fiber tract,vMP2 tract,MP1 tract,thoracic-abdominal pioneer tract,dMP2 neuron,vMP2 neuron,MP1 neuron,pCC neuron,intersegmental nerve" FBgn0024266 acd(2)5F3 auditory courtship defective 5F3 http://flybase.org/reports/FBgn0024266 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5F3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective" FBgn0033394 CG13740 - http://flybase.org/reports/FBgn0033394 protein_coding_gene - - - CG13740 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062525 l(3)88EFg lethal (3) 88EFg http://flybase.org/reports/FBgn0062525 gene - - - l(3)88EFg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0017416 bac backwards http://flybase.org/reports/FBgn0017416 - gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bac - - 11-Aug-17 DroID_v2017_08 - - - - - - "chordotonal organ & axon | lateral,commissure" FBgn0085717 CG41599 - http://flybase.org/reports/FBgn0085717 protein_coding_gene - - - CG41599 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063424 l(2)44CDa lethal (2) 44CDa http://flybase.org/reports/FBgn0063424 gene - - - l(2)44CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005077 fs(2)OW801 female sterile (2) OW801 http://flybase.org/reports/FBgn0005077 - gene - - - fs(2)OW801 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036094 CG14153 - http://flybase.org/reports/FBgn0036094 protein_coding_gene - - - CG14153 - CG14153 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026628 noco noco http://flybase.org/reports/FBgn0026628 - gene molecular_function ; GO:0003674 | no biological data available central nervous system development ; GO:0007417 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available noco - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic/larval central nervous system,longitudinal connective" FBgn0001026 fs(3)A17 female sterile (3) A17 http://flybase.org/reports/FBgn0001026 - gene - - - fs(3)A17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "ovary,oocyte" FBgn0035800 CG7716 - http://flybase.org/reports/FBgn0035800 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin binding ; GO:0043015 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 microtubule minus-end binding ; GO:0051011 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000447085 mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 centrosome duplication ; GO:0051298 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 meiotic nuclear division ; GO:0007126 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 interphase microtubule nucleation by interphase microtubule organizing center ; GO:0051415 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 equatorial microtubule organizing center ; GO:0000923 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin small complex ; GO:0008275 | inferred from biological aspect of ancestor with PANTHER:PTN000447206 CG7716 IPR007259:Gamma-tubulin complex component protein CG7716 11-Aug-17 DroID_v2017_08 "Drer\tubgcp3, Drer\tubgcp4, Drer\tubgcp2" "Scer\SPC98, Scer\SPC97" Cele\gip-1 "Xtro\tubgcp4, Xtro\tubgcp3, Xtro\tubgcp2" "Mmus\Tubgcp4, Mmus\Tubgcp2, Mmus\Tubgcp3" "Hsap\TUBGCP2, Hsap\TUBGCP3, Hsap\TUBGCP4" viable FBgn0264660 short-round short round http://flybase.org/reports/FBgn0264660 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - short-round - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,embryonic/larval dorsal trunk" FBgn0020642 Lcp65Ac Lcp65Ac http://flybase.org/reports/FBgn0020642 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence or structural similarity structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "DCP2, DMLCP65c, Lcp-c, CG6956, Lcp65Ac, LCP65Ac" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG6956 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " embryonic stage , larval stage , pupal stage | 7-13 hr " "partially lethal - majority die,some die during pupal stage,viable" FBgn0004063 cwi crumpled wings http://flybase.org/reports/FBgn0004063 - gene - - - cwi - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,heat sensitive" wing FBgn0263498 CR43487 - http://flybase.org/reports/FBgn0263498 non_protein_coding_gene - - - "CR43487, lincRNA.695" - CR43487 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050056 CG30056 - http://flybase.org/reports/FBgn0050056 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs33g02, NEST:bs07h07, NEST:bs07b11, CG30056" - CG30056 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0067344 l(3)L1M lethal (3) L1M http://flybase.org/reports/FBgn0067344 gene - - - l(3)L1M - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during third instar larval stage" FBgn0266870 CR45331 - http://flybase.org/reports/FBgn0266870 non_protein_coding_gene - - - CR45331 - CR45331 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260013 blv bolivar http://flybase.org/reports/FBgn0260013 gene - karyosome formation ; GO:0030717 | inferred from mutant phenotype - blv - - 11-Aug-17 DroID_v2017_08 - - - - - - "chorion | germline clone,karyosome,chorion" FBgn0060846 l(3)S048718 lethal (3) S048718 http://flybase.org/reports/FBgn0060846 gene - - - "0487/18, l(3)S048718" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267365 l(2)SH0834 lethal (2) SH0834 http://flybase.org/reports/FBgn0267365 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "l(2)SH0834, CG5385, l(2)SH2 0834" - CG5385 11-Aug-17 DroID_v2017_08 - - - - - - DRSC02854 E -0.941651068 -0.655406794 0.217581508 -1.940626876 -0.241153634 0.739493771 FBgn0000178 bhe broad head http://flybase.org/reports/FBgn0000178 - gene molecular_function ; GO:0003674 | no biological data available head involution ; GO:0008258 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bhe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" embryonic head FBgn0027636 ms(1)12 male sterile (1) 12 http://flybase.org/reports/FBgn0027636 - gene - - - ms(1)12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile" FBgn0040896 CG14775 - http://flybase.org/reports/FBgn0040896 protein_coding_gene - - - "BcDNA:GH26828, CG14775" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040937 CG15248 - http://flybase.org/reports/FBgn0040937 protein_coding_gene - - - CG15248 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069192 l(3)L0189 lethal (3) L0189 http://flybase.org/reports/FBgn0069192 gene - - - l(3)L0189 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052240 CG32240 - http://flybase.org/reports/FBgn0052240 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH04494, BcDNA:GH04494, CG32240" - CG32240 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035263 CG12035 - http://flybase.org/reports/FBgn0035263 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG12035 - CG12035 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08238 E -0.486994658 -0.395484099 -1.576903366 -0.100743413 -0.131672173 -0.34905406 FBgn0019714 l(2)46CFn lethal (2) 46CFn http://flybase.org/reports/FBgn0019714 - gene - - - "19.22, l(2)46CFn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval digestive system,presumptive embryonic/larval tracheal system" FBgn0265731 CR44538 - http://flybase.org/reports/FBgn0265731 non_protein_coding_gene - - - "CR44538, incRNA.488, lincRNA.488, R5_3L:10198772..10199539" - CR44538 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264691 Lst8 Lst8 http://flybase.org/reports/FBgn0264691 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of actin cytoskeleton organization ; GO:0032956 | inferred from biological aspect of ancestor with PANTHER:PTN000457085 positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype TOR signaling ; GO:0031929 | inferred from physical interaction with Tor cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9Z2K5 TORC1 complex ; GO:0031931 | inferred from biological aspect of ancestor with PANTHER:PTN000457085 TORC2 complex ; GO:0031932 | inferred from biological aspect of ancestor with PANTHER:PTN000457085 "lst8, CG3004, dLST8, dGbetaL, Lst8, Gbl" "IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like" CG3004 11-Aug-17 DroID_v2017_08 Drer\mlst8 Scer\LST8 Cele\C10H11.8 Xtro\mlst8 Mmus\Mlst8 "Hsap\PREB, Hsap\MLST8" FBgn0014239 l(2)31Fa lethal (2) 31Fa http://flybase.org/reports/FBgn0014239 - gene - - - l(2)31Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000934 fs(2)A4 female sterile (2) A4 http://flybase.org/reports/FBgn0000934 - gene - - - fs(2)A4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0265765 CR44572 - http://flybase.org/reports/FBgn0265765 non_protein_coding_gene - - - CR44572 - CR44572 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267726 CG46059 - http://flybase.org/reports/FBgn0267726 protein_coding_gene - - - "CG46059, CR17567, CG17567" - CG46059 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065552 l(2)SH1033 lethal (2) SH1033 http://flybase.org/reports/FBgn0065552 gene - - - "l(2)SH1033, l(2)SH2 1033" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032513 CG6565 - http://flybase.org/reports/FBgn0032513 protein_coding_gene lipid binding ; GO:0008289 | inferred from electronic annotation with InterPro:IPR002913 - - CG6565 "IPR002913:START domain, IPR023393:START-like domain" CG6565 11-Aug-17 DroID_v2017_08 "Drer\stard7, Drer\pctp, Drer\stard10" - "Cele\T28D6.7, Cele\C06H2.2" "Xtro\LOC496503, Xtro\stard7" "Mmus\Stard7, Mmus\Pctp, Mmus\Stard10" "Hsap\STARD7, Hsap\PCTP" FBgn0028079 l(3)S086112 lethal (3) S086112 http://flybase.org/reports/FBgn0028079 gene - - - "0861/12, l(3)S086112" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027621 Pfrx 6-phosphofructo-2-kinase http://flybase.org/reports/FBgn0027621 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003094, InterPro:IPR013079 6-phosphofructo-2-kinase activity ; GO:0003873 | inferred from sequence or structural similarity with HGNC:8873 fructose-2,6-bisphosphate 2-phosphatase activity ; GO:0004331 | inferred from sequence or structural similarity with SGD:S000003691" "fructose metabolic process ; GO:0006000 | inferred from electronic annotation with InterPro:IPR013079 fructose 2,6-bisphosphate metabolic process ; GO:0006003 | inferred from electronic annotation with InterPro:IPR003094 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:8873 glycolytic process ; GO:0006096 | inferred from sequence or structural similarity with HGNC:8873 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003691 "CG3400, Pfrx, PFK2" "IPR001345:Phosphoglycerate/bisphosphoglycerate mutase, active site, IPR003094:Fructose-2,6-bisphosphatase, IPR013078:Histidine phosphatase superfamily, clade-1, IPR013079:6-phosphofructo-2-kinase, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR029033:Histidine phosphatase superfamily" CG3400 11-Aug-17 DroID_v2017_08 "Drer\pfkfb2a, Drer\pfkfb4b, Drer\pfkfb1, Drer\pfkfb4a, Drer\pfkfb3, Drer\si:dkey-96f10.1, Drer\pfkfb2b" "Scer\PFK27, Scer\PFK26, Scer\FBP26, Scer\YLR345W" "Cele\pfkb-1.2, Cele\pfkb-1.1" "Xtro\pfkfb3, Xtro\pfkfb4, Xtro\pfkfb2, Xtro\pfkfb1" "Mmus\Pfkfb4, Mmus\Pfkfb1, Mmus\Pfkfb2, Mmus\Pfkfb3" "Hsap\PFKFB1, Hsap\PFKFB2, Hsap\PFKFB4, Hsap\PFKFB3" "chemical resistant,viable,sleep defective,partially lethal - majority die,visible,partially lethal,conditional" mesothoracic tergum FBgn0046319 412\sORF2 412 element sORF2 http://flybase.org/reports/FBgn0046319 transposable_element_gene - - - 412\sORF2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036929 CG7668 - http://flybase.org/reports/FBgn0036929 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "BcDNA:GM07843, BcDNA:RE40293, CG7668, AAF49079, AAN11645, AAM11109, FBpp0074674, FBpp0074673" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG7668 11-Aug-17 DroID_v2017_08 "Drer\angpt4, Drer\si:dkeyp-51b7.3, Drer\fibcd1, Drer\angpt1, Drer\si:zfos-2330d3.6, Drer\LOC555374, Drer\zmp:0000000846, Drer\fgb, Drer\mfap4, Drer\angptl2b, Drer\fgl1, Drer\si:zfos-2330d3.1, Drer\tnc, Drer\angptl3, Drer\wu:fj11g02, Drer\zgc:173915, Drer\angptl5, Drer\fgl2a, Drer\angptl2a, Drer\fga, Drer\zgc:194887, Drer\angptl4, Drer\si:ch1073-110a20.2, Drer\si:ch1073-110a20.1, Drer\LOC100007488, Drer\zgc:171687, Drer\angptl1a, Drer\tnw, Drer\si:zfos-2330d3.3, Drer\si:ch211-203k16.3, Drer\si:ch211-157b11.8, Drer\si:ch211-287a12.9, Drer\angpt2a, Drer\angpt2b, Drer\tnr, Drer\fgl2b, Drer\fgg, Drer\angptl7, Drer\si:zfos-2330d3.8, Drer\si:ch1073-110a20.3, Drer\tnxba, Drer\angptl6" Scer\SMC1 "Cele\ensh-1, Cele\Y69H2.3, Cele\Y26D4A.12, Cele\C08G9.2, Cele\Y69H2.10, Cele\T15B7.1, Cele\eea-1, Cele\Y43C5A.2, Cele\C49C8.5, Cele\W05B2.2, Cele\F40A3.2, Cele\K10D3.4, Cele\ZC504.1" "Xtro\fcn3, Xtro\angpt1, Xtro\LOC100491105, Xtro\fcn2, Xtro\fga, Xtro\LOC100488177, Xtro\fibcd1, Xtro\tnc, Xtro\angpt4, Xtro\tnxb, Xtro\mfap4, Xtro\fgg, Xtro\fgl2, Xtro\fgb, Xtro\angptl5, Xtro\tnn, Xtro\angptl2, Xtro\angptl4, Xtro\fgl1, Xtro\fcn1, Xtro\LOC100497330, Xtro\angptl3, Xtro\tnr" "Mmus\Angptl6, Mmus\Fgl2, Mmus\Fga, Mmus\Angptl4, Mmus\Fgb, Mmus\Tnr, Mmus\Angptl1, Mmus\Tnc, Mmus\Fcnb, Mmus\Fibcd1, Mmus\Fgg, Mmus\Angpt1, Mmus\Mfap4, Mmus\Angpt2, Mmus\Angpt4, Mmus\Angptl7, Mmus\Fcna, Mmus\Angptl2, Mmus\Tnxb, Mmus\Fgl1, Mmus\Tnn, Mmus\Angptl3" "Hsap\TNC, Hsap\FCN2, Hsap\FGA, Hsap\ANGPTL7, Hsap\ANGPTL5, Hsap\TNXB, Hsap\FIBCD1, Hsap\ANGPTL6, Hsap\ANGPTL4, Hsap\FGL1, Hsap\FGL2, Hsap\TNR, Hsap\MFAP4, Hsap\ANGPT1, Hsap\ANGPT4, Hsap\FGB, Hsap\ANGPTL2, Hsap\ANGPTL3, Hsap\ANGPT2, Hsap\ANGPTL1, Hsap\FGG, Hsap\TNN, Hsap\FCN3, Hsap\FCN1" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0052170 CG32170 - http://flybase.org/reports/FBgn0052170 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT12913, BcDNA:RE28470, CG32170" - CG32170 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026301 anon-7Ab anon-7Ab http://flybase.org/reports/FBgn0026301 - gene - - - "t2, anon-7Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085598 CG41283 - http://flybase.org/reports/FBgn0085598 protein_coding_gene - - - CG41283 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015897 anon-99Da anon-99Da http://flybase.org/reports/FBgn0015897 - gene - - - anon-99Da - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036392 CG17363 - http://flybase.org/reports/FBgn0036392 protein_coding_gene - - - CG17363 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031289 CG13950 - http://flybase.org/reports/FBgn0031289 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR001079 - - CG13950 "IPR001079:Galectin, carbohydrate recognition domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG13950 11-Aug-17 DroID_v2017_08 "Drer\lgals9l5, Drer\lgalsla, Drer\lgalslb, Drer\lgals1l1, Drer\grifin, Drer\lgals9l3, Drer\lgals8a, Drer\lgals8b, Drer\lgals9l4, Drer\lgals9l6, Drer\lgals9l1, Drer\lgals3b, Drer\si:ch211-10a23.2, Drer\lgals3a" - "Cele\lec-5, Cele\lec-3, Cele\lec-12, Cele\lec-10, Cele\lec-4, Cele\lec-2, Cele\C27C7.5, Cele\lec-1, Cele\lec-8, Cele\lec-11" "Xtro\lgals4, Xtro\lgals9b, Xtro\lgals3, Xtro\lgals1, Xtro\lgals8, Xtro\lgalsl, Xtro\lgals9, Xtro\LOC100496749, Xtro\LOC100216286, Xtro\lgals2" "Mmus\Lgalsl, Mmus\Lgals9, Mmus\Lgals4, Mmus\Lgals12, Mmus\Lgals3, Mmus\Lgals2, Mmus\Lgals1, Mmus\Lgals8, Mmus\Lgals7, Mmus\Grifin" "Hsap\LGALS13, Hsap\LGALS4, Hsap\CLC, Hsap\OSTC, Hsap\LGALSL, Hsap\LGALS9B, Hsap\LGALS3, Hsap\LGALS14, Hsap\LGALS7B, Hsap\LGALS2, Hsap\LGALS12, Hsap\LGALS9C, Hsap\LGALS8, Hsap\LGALS1, Hsap\LGALS9, Hsap\LGALS7" viable FBgn0002826 ms(2)E5 male sterile (2) E5 http://flybase.org/reports/FBgn0002826 - gene - - - "ms2.5, ms(2)2.5, ms(2)E5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0044403 Scim24 Sensitized chromosome inheritance modifier 24 http://flybase.org/reports/FBgn0044403 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype - Scim24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" mitosis & nuclear chromosome FBgn0000702 fltH flight defective H http://flybase.org/reports/FBgn0000702 - gene - - - fltH - - 11-Aug-17 DroID_v2017_08 - - - - - - flightless "myofibril,flight muscle,Z disc,striated muscle thin filament,striated muscle myosin thick filament,sarcomere" FBgn0067732 l(1)G0502 lethal (1) G0502 http://flybase.org/reports/FBgn0067732 gene - - - l(1)G0502 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013709 mt:tRNA:Trp-TCA mitochondrial transfer RNA:Tryptophan-TCA http://flybase.org/reports/FBgn0013709 FBgn0002867 tRNA_gene - - - "CR34064, tRNA[Trp], tRNAtrp, mtdbD00006295, mt:tRNA:Trp-TCA, mt:tRNA:W" - CR34064 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266676 CR45166 - http://flybase.org/reports/FBgn0266676 non_protein_coding_gene - - - CR45166 - CR45166 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035438 PHGPx PHGPx http://flybase.org/reports/FBgn0035438 protein_coding_gene peroxidase activity ; GO:0004601 | inferred from direct assay glutathione peroxidase activity ; GO:0004602 | inferred from sequence or structural similarity with UniProtKB:P36969 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000889 response to lipid hydroperoxide ; GO:0006982 | inferred from sequence or structural similarity with UniProtKB:P36969 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P36969 Golgi apparatus ; GO:0005794 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P36969 "CG12013, DmPHGPx, anon-WO0257455.17, PHGPx, GTPx-1, GPx, DmGPx, PGTPx, Gtpx-1, GTPx, phGpx, Tpx1, Gpx" "IPR000889:Glutathione peroxidase, IPR012336:Thioredoxin-like fold" CG12013 11-Aug-17 DroID_v2017_08 "Drer\gpx7, Drer\gpx4b, Drer\si:ch73-111m19.2, Drer\gpx8, Drer\gpx1a, Drer\gpx4a, Drer\gpx1b, Drer\gpx3" "Scer\GPX1, Scer\HYR1, Scer\GPX2" "Cele\gpx-7, Cele\gpx-6, Cele\gpx-1, Cele\gpx-2, Cele\gpx-8" "Xtro\gpx1, Xtro\gpx7, Xtro\gpx3" "Mmus\Gpx3, Mmus\Gpx7, Mmus\Gpx1, Mmus\Gpx5, Mmus\Gpx4, Mmus\Gpx2, Mmus\Gpx6, Mmus\Gpx8" "Hsap\GPX6, Hsap\GPX8, Hsap\GPX3, Hsap\GPX5, Hsap\GPX4, Hsap\GPX2, Hsap\GPX1, Hsap\GPX7" oxidative stress response defective FBgn0011116 l(1)Q77 lethal (1) Q77 http://flybase.org/reports/FBgn0011116 FBgn0010210 gene - - - l(1)Q77 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261736 EC2519 - http://flybase.org/reports/FBgn0261736 gene - - - EC2519 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0014879 Set Set http://flybase.org/reports/FBgn0014879 - protein_coding_gene - nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR002164 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR002164 "CG4299, SET, Set, TAF-Ibeta, dSET, dSet" IPR002164:Nucleosome assembly protein (NAP) CG4299 11-Aug-17 DroID_v2017_08 "Drer\pkn2, Drer\pkn1a, Drer\setb, Drer\tspy, Drer\seta, Drer\pkn1b, Drer\hsf5, Drer\zgc:153916" Scer\VPS75 "Cele\pkn-1, Cele\spr-2" "Xtro\tspyl2, Xtro\set, Xtro\pkn3" "Mmus\Tspyl5, Mmus\Tspyl3, Mmus\Tspyl2, Mmus\Tspyl4, Mmus\Pkn1, Mmus\Set, Mmus\Tspyl1, Mmus\Pkn3, Mmus\Hsf5, Mmus\Pkn2" "Hsap\TSPYL5, Hsap\TSPY1, Hsap\TSPY10, Hsap\TSPY8, Hsap\TSPY4, Hsap\PKN1, Hsap\TSPYL2, Hsap\SETSIP, Hsap\TSPYL1, Hsap\TSPYL4, Hsap\PKN2, Hsap\PKN3, Hsap\HSF5, Hsap\SET, Hsap\TSPYL6, Hsap\TSPY2, Hsap\TSPY3" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0020010 Fas1::Nrg Fas1::Nrg http://flybase.org/reports/FBgn0020010 - engineered_fusion_gene - - - Fas1::Nrg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058191 CG40191 - http://flybase.org/reports/FBgn0058191 protein_coding_gene - - - "BEST:HL02313, BcDNA:LD12604, CG40191" IPR013763:Cyclin-like CG40191 11-Aug-17 DroID_v2017_08 Drer\cnppd1 "Scer\PCL2, Scer\PCL1, Scer\PCL10, Scer\PCL6, Scer\PCL7, Scer\PCL5, Scer\CLG1, Scer\PCL8, Scer\PHO80, Scer\PCL9" Cele\F09G2.2 Xtro\cnppd1 Mmus\Cnppd1 Hsap\CNPPD1 DRSC21041 I -1.926119769 -0.024157811 -0.166481402 -0.005783387 0.773604807 0.282398526 FBgn0003198 rags rags http://flybase.org/reports/FBgn0003198 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "rag, rags" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0037100 CapaR Capability receptor http://flybase.org/reports/FBgn0037100 protein_coding_gene neuromedin U receptor activity ; GO:0001607 | inferred from electronic annotation with InterPro:IPR005390 neuropeptide receptor activity ; GO:0008188 | inferred from direct assay inferred from physical interaction with Capa neuropeptide receptor activity ; GO:0008188 | inferred from physical interaction with Capa neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model positive regulation of calcium ion transport ; GO:0051928 | inferred from mutant phenotype cellular response to desiccation ; GO:0071465 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay body fluid secretion ; GO:0007589 | traceable author statement "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR005390, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model basolateral plasma membrane ; GO:0016323 | inferred from direct assay" "CG14575, Dm CG14575, CapaR, capaR, CAP2B-R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR005390:Neuromedin U receptor, IPR017452:GPCR, rhodopsin-like, 7TM" CG14575 11-Aug-17 DroID_v2017_08 "Drer\or128-9, Drer\or122-2, Drer\nmur1a, Drer\or115-1, Drer\mlnr, Drer\LOC101885849, Drer\or124-1, Drer\or115-11, Drer\nmur3, Drer\ghsra, Drer\or102-5, Drer\or113-2, Drer\LOC101885431, Drer\or127-1, Drer\or114-1, Drer\LOC103910036, Drer\or110-2, Drer\gpr39, Drer\LOC101885494, Drer\ghsrb, Drer\nmur1b, Drer\ntsr1, Drer\or122-1, Drer\or104-2, Drer\or108-3, Drer\or113-1" - "Cele\srw-40, Cele\srw-140, Cele\srw-133, Cele\dmsr-1, Cele\srw-2, Cele\srw-118, Cele\srw-134, Cele\srw-124, Cele\srw-72, Cele\srw-6, Cele\srw-122, Cele\srw-76, Cele\srw-54, Cele\srw-127, Cele\nmur-2, Cele\srw-144, Cele\srw-48, Cele\srw-79, Cele\srw-87, Cele\nmur-3, Cele\dmsr-14, Cele\srw-66, Cele\srw-115, Cele\srw-23, Cele\srw-84, Cele\srw-138, Cele\srw-3, Cele\srw-120, Cele\srw-90, Cele\srw-68, Cele\srw-77, Cele\srw-10, Cele\srw-26, Cele\srw-130, Cele\srw-51, Cele\srw-123, Cele\srw-22, Cele\srw-143, Cele\srw-53, Cele\srw-55, Cele\srw-14, Cele\srw-117, Cele\srw-31, Cele\srw-101, Cele\srw-9, Cele\srw-17, Cele\srw-141, Cele\srw-71, Cele\srw-56, Cele\srw-8, Cele\srw-137, Cele\srw-119, Cele\srw-15, Cele\srw-61, Cele\srw-21, Cele\srw-91, Cele\srw-60, Cele\srw-59, Cele\srw-139, Cele\srw-1, Cele\srw-113, Cele\dmsr-9, Cele\srw-24, Cele\srw-103, Cele\srw-111, Cele\srw-32, Cele\srw-38, Cele\nmur-1, Cele\srw-65, Cele\srw-13, Cele\srw-95, Cele\srw-99, Cele\srw-34, Cele\srw-75, Cele\srw-83, Cele\srw-100, Cele\srw-109, Cele\srw-7, Cele\srw-142, Cele\srw-20, Cele\srw-112, Cele\srw-44, Cele\srw-19, Cele\srw-97, Cele\npr-32, Cele\srw-136, Cele\srw-102, Cele\srw-121, Cele\srw-129, Cele\srw-63, Cele\srw-82, Cele\srw-107" Xtro\nmur2 "Mmus\Olfr1182, Mmus\Olfr116, Mmus\Nmur2, Mmus\Olfr350, Mmus\Nmur1, Mmus\Olfr125, Mmus\Olfr358, Mmus\Ntsr1, Mmus\Olfr64, Mmus\Gpr39, Mmus\Olfr270, Mmus\Olfr397, Mmus\Olfr307, Mmus\Olfr114, Mmus\Olfr1051, Mmus\Olfr1180, Mmus\Olfr972, Mmus\Olfr165, Mmus\Olfr556, Mmus\Olfr1080, Mmus\Olfr701, Mmus\Olfr1189, Mmus\Olfr693, Mmus\Ghsr, Mmus\Olfr127, Mmus\Olfr1049, Mmus\Olfr112, Mmus\Olfr1048, Mmus\Olfr384, Mmus\Olfr385, Mmus\Olfr606, Mmus\Olfr1184, Mmus\Olfr361, Mmus\Olfr126, Mmus\Ntsr2" "Hsap\P2RY8, Hsap\OR4C15, Hsap\OR4P4, Hsap\NMUR2, Hsap\NTSR2, Hsap\OR2M3, Hsap\OR6B1, Hsap\GHSR, Hsap\MLNR, Hsap\GPR39, Hsap\OR51E1, Hsap\NTSR1, Hsap\NMUR1, Hsap\OR2T6, Hsap\OR8K5, Hsap\GPR148" starvation stress response defective FBgn0037038 CG11037 - http://flybase.org/reports/FBgn0037038 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 extracellular space ; GO:0005615 | inferred from direct assay "SP191, CG11037" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG11037 11-Aug-17 DroID_v2017_08 Drer\si:dkey-21e2.15 - "Cele\try-5, Cele\try-1, Cele\svh-1" - - Hsap\CMA1 FBgn0004053 zen zerknullt http://flybase.org/reports/FBgn0004053 "FBgn0013967, FBgn0019915" protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" negative regulation of gene expression ; GO:0010629 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay compound eye development ; GO:0048749 | inferred from mutant phenotype amnioserosa formation ; GO:0007378 | traceable author statement dorsal/ventral axis specification ; GO:0009950 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype - "ZEN VRE, zen1, z1, l(3)84Ad, CG1046, BG:DS00276.9, zen, Zen, ZEN, dm-zen" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG1046 11-Aug-17 DroID_v2017_08 "Drer\meox2a, Drer\mnx1, Drer\hoxb1b, Drer\hoxa5a, Drer\hoxc8a, Drer\hoxc3a, Drer\hoxa3a, Drer\hoxd4a, Drer\hoxc6b, Drer\hoxb7a, Drer\hoxb5b, Drer\gbx1, Drer\hoxd3a, Drer\hoxb5a, Drer\hoxc6a, Drer\hoxb4a, Drer\hoxb3a, Drer\hoxc1a, Drer\gsx2, Drer\hoxc4a, Drer\meox2b, Drer\hoxa9b, Drer\hoxb8b, Drer\gsx1, Drer\hoxc5a, Drer\gbx2, Drer\pdx1, Drer\hoxb6a, Drer\hoxa2b, Drer\nkx2.2a, Drer\hoxb6b, Drer\mnx2a, Drer\hoxa4a, Drer\meox1, Drer\hoxb1a, Drer\hoxa1a, Drer\hoxb2a" "Scer\YLR053C, Scer\YOX1, Scer\YHP1, Scer\PHO2" "Cele\smi-1, Cele\ceh-13, Cele\mab-5, Cele\nob-1, Cele\ceh-22, Cele\lin-39, Cele\col-122" "Xtro\hoxb3, Xtro\hoxc3, Xtro\gsx1, Xtro\gbx2.1, Xtro\hoxb5, Xtro\hoxb7, Xtro\hoxa2, Xtro\hoxa3, Xtro\hoxa5, Xtro\mnx1, Xtro\meox2, Xtro\hoxb8, Xtro\hoxb4, Xtro\hoxa1, Xtro\gsx2, Xtro\hoxd1, Xtro\pdx1, Xtro\hoxd8, Xtro\hoxb6, Xtro\hoxb2, Xtro\hoxb1, Xtro\hoxc5, Xtro\hoxc8, Xtro\hoxd3, Xtro\gbx2.2, Xtro\hoxc4" "Mmus\Hoxc6, Mmus\Hoxb3, Mmus\Hoxc8, Mmus\Hoxa1, Mmus\Nkx2-2, Mmus\Meox2, Mmus\Hoxb6, Mmus\Hoxd4, Mmus\Hoxb8, Mmus\Mnx1, Mmus\Hoxd1, Mmus\Hoxb4, Mmus\Hoxa2, Mmus\Hoxc5, Mmus\Hoxb1, Mmus\Hoxd8, Mmus\Pdx1, Mmus\Hoxa7, Mmus\Hoxa5, Mmus\Hoxb7, Mmus\Meox1, Mmus\Hoxc4, Mmus\Gbx1, Mmus\Gemin2, Mmus\Hoxb2, Mmus\Hoxb5, Mmus\Gbx2, Mmus\Hoxa6, Mmus\Hoxa4, Mmus\Hoxd3, Mmus\Gsx1, Mmus\Hoxa3, Mmus\Gsx2" "Hsap\HOXD3, Hsap\HOXA4, Hsap\HOXB6, Hsap\HOXB7, Hsap\HOXA2, Hsap\HOXD1, Hsap\GSX1, Hsap\HOXB4, Hsap\HOXA6, Hsap\HOXA3, Hsap\HOXD8, Hsap\HOXB3, Hsap\HOXD4, Hsap\GSX2, Hsap\HOXC6, Hsap\HOXC8, Hsap\GBX1, Hsap\HOXC4, Hsap\NKX2-2, Hsap\HOXB2, Hsap\HOXC5, Hsap\MNX1, Hsap\GBX2, Hsap\HOXB1, Hsap\PDX1, Hsap\HOXB8, Hsap\HOXB5, Hsap\HOXA7, Hsap\MEOX2, Hsap\HOXA1, Hsap\SMAD4, Hsap\MEOX1, Hsap\HOXA5" " embryonic stage | extended germ band , embryonic stage | stage 3 , embryonic stage | embryonic cycle 14 , embryonic stage , embryonic stage | stage 7-10 , embryonic stage | stage 4-6 , embryonic stage | stage 6-7 , embryonic stage | gastrula , embryonic stage | stage 4 " " dorsal ectoderm | restricted

, pole cell | restricted

,

dorsal <&> anterior embryo <&> posterior embryo , dorsal ectoderm

, amnioserosa primordium

,organism | dorsal , amnioserosa

" embryonic stage | stage 3-11 dorsal ectoderm | restricted

"lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal,heat sensitive,viable,recessive" "optic lobe,embryonic head,extended germ band embryo,cuticle,denticle belt,presumptive embryonic/larval central nervous system,ectoderm,dorsal,embryonic head epidermis,embryonic optic lobe primordium,retina,ventral" FBgn0041706 CG3253 - http://flybase.org/reports/FBgn0041706 protein_coding_gene - - - "BEST:GH04269, CG3253, dibeta3GnT1" IPR029044:Nucleotide-diphospho-sugar transferases CG3253 11-Aug-17 DroID_v2017_08 "Drer\xxylt1, Drer\gxylt1b, Drer\gxylt2, Drer\b4gat1, Drer\large, Drer\gxylt1a, Drer\gyltl1b" - "Cele\bgnt-1.6, Cele\bgnt-1.7, Cele\bgnt-1.1, Cele\lge-1, Cele\bgnt-1.5, Cele\bgnt-1.3, Cele\bgnt-1.4, Cele\bgnt-1.8, Cele\bgnt-1.2" "Xtro\gxylt1, Xtro\large, Xtro\gxylt2, Xtro\gyltl1b, Xtro\b4gat1, Xtro\xxylt1" "Mmus\Gxylt1, Mmus\Large2, Mmus\Gxylt2, Mmus\Xxylt1, Mmus\B4gat1, Mmus\Large1" "Hsap\LARGE1, Hsap\GXYLT2, Hsap\LARGE2, Hsap\XXYLT1, Hsap\GXYLT1, Hsap\B4GAT1" viable FBgn0000244 by blistery http://flybase.org/reports/FBgn0000244 "FBgn0021752, FBgn0037704, FBgn0047068" protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement focal adhesion ; GO:0005925 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from sequence or structural similarity "3R-B, CG9379, CT26639, BcDNA:RE65113, by" "IPR000980:SH2 domain, IPR013625:Tensin/EPS8 phosphotyrosine-binding domain, IPR033929:Tensin, phosphotyrosine-binding domain, IPR011993:PH domain-like, IPR006020:PTB/PI domain" CG9379 11-Aug-17 DroID_v2017_08 "Drer\tns1b, Drer\tns2b, Drer\si:ch211-191a24.3, Drer\tns1a, Drer\tns2a" Scer\TEP1 "Cele\tns-1, Cele\shc-2" "Xtro\tns1, Xtro\tns2" "Mmus\Tns1, Mmus\Tns3, Mmus\Tns4, Mmus\Tns2" "Hsap\TNS1, Hsap\TNS2, Hsap\TNS4, Hsap\TNS3" " larval stage | third instar , embryonic stage -- adult stage " " dorsal mesothoracic disc

, organism

" "visible,female sterile,partially,recessive,viable,somatic clone,increased cell death" "wing,thorax,somatic clone,distal,wing disc" FBgn0082192 arr::LpR2 arr::LpR2 http://flybase.org/reports/FBgn0082192 engineered_fusion_gene - - - arr::LpR2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259445 C904.1 - http://flybase.org/reports/FBgn0259445 gene - - - C904.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0263463 snoRNA:gcl-a - http://flybase.org/reports/FBgn0263463 snoRNA_gene - - - "snoRNA:gcl-a, ncRNA_47" - CR43578 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266099 CG44836 - http://flybase.org/reports/FBgn0266099 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG44836, CG13035, CG13036" - CG44836 11-Aug-17 DroID_v2017_08 - Scer\RCM1 Cele\nsun-5 - Mmus\Nsun7 Hsap\NSUN7 FBgn0263409 CR43455 - http://flybase.org/reports/FBgn0263409 non_protein_coding_gene - - - CR43455 - CR43455 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013488 l(1)6PP19 lethal (1) 6PP19 http://flybase.org/reports/FBgn0013488 - gene - - - l(1)6PP19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg" FBgn0260620 2L2834 - http://flybase.org/reports/FBgn0260620 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2834 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0027974 l(3)S140410 lethal (3) S140410 http://flybase.org/reports/FBgn0027974 gene - - - "l(3)S140410, l(3)s140410" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266268 FeCH Ferrochelatase http://flybase.org/reports/FBgn0266268 protein_coding_gene ferrochelatase activity ; GO:0004325 | inferred from sequence or structural similarity with UniProtKB:P22830 ferrochelatase activity ; GO:0004325 | inferred from direct assay protoporphyrinogen IX biosynthetic process ; GO:0006782 | inferred from sequence or structural similarity with UniProtKB:P22830 microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:P22830 "FeCH, ferrochelatase, CG2098" "IPR001015:Ferrochelatase, IPR019772:Ferrochelatase, active site, IPR033644:Ferrochelatase, C-terminal, IPR033659:Ferrochelatase, N-terminal" CG2098 11-Aug-17 DroID_v2017_08 Drer\fech Scer\HEM15 Cele\fecl-1 Xtro\fech Mmus\Fech Hsap\FECH FBgn0030418 CG4004 - http://flybase.org/reports/FBgn0030418 protein_coding_gene - - nucleus ; GO:0005634 | inferred from direct assay "CG18137, CG4004" IPR006578:MADF domain CG4004 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0022188 l(2)k05125a lethal (2) k05125a http://flybase.org/reports/FBgn0022188 - gene - - - "l(2)k05125, l(2)k05125a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035813 CG8492 - http://flybase.org/reports/FBgn0035813 protein_coding_gene - - - CG8492 "IPR001916:Glycoside hydrolase, family 22, IPR023346:Lysozyme-like domain, IPR019799:Glycoside hydrolase, family 22, conserved site" CG8492 11-Aug-17 DroID_v2017_08 "Drer\lyz, Drer\LOC100536671, Drer\LOC100334363" - - Xtro\MGC89221 "Mmus\Spaca3, Mmus\Spaca1, Mmus\Spaca7, Mmus\1700016D06Rik, Mmus\Lyzl1, Mmus\Spaca4, Mmus\Lyz1, Mmus\Lyzl4, Mmus\Spaca5, Mmus\Lyz2, Mmus\Lyzl6, Mmus\Lalba, Mmus\9530003J23Rik" "Hsap\LYZL2, Hsap\LALBA, Hsap\SPACA7, Hsap\LYZL6, Hsap\LYZL4, Hsap\SPACA3, Hsap\SPACA1, Hsap\LYZL1, Hsap\SPACA4, Hsap\LYZ, Hsap\SPACA5B, Hsap\SPACA5" "viable,stress response defective" DRSC21804 E 0.109284277 0.141112226 -0.361710087 -1.585771903 0.601162665 -0.427685864 FBgn0025152 ms(2)A4 ms(2)A4 http://flybase.org/reports/FBgn0025152 - gene - - - ms(2)A4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0004977 Ata Arista http://flybase.org/reports/FBgn0004977 - gene - - - "At, Ata" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" "arista,wing hair,wing" FBgn0016836 l(1)MZ4 lethal (1) MZ4 http://flybase.org/reports/FBgn0016836 - gene - - - "l(1)MZ4, M4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031423 CG3557 - http://flybase.org/reports/FBgn0031423 protein_coding_gene - - - CG3557 - CG3557 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0266946 CR45397 - http://flybase.org/reports/FBgn0266946 non_protein_coding_gene - - - CR45397 - CR45397 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265996 CR44771 - http://flybase.org/reports/FBgn0265996 non_protein_coding_gene - - - "CR44771, lincRNA.144, R5_2L:15159441..15160073" - CR44771 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265965 CR44752 - http://flybase.org/reports/FBgn0265965 non_protein_coding_gene - - - CR44752 - CR44752 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265551 CR44401 - http://flybase.org/reports/FBgn0265551 non_protein_coding_gene - - - CR44401 - CR44401 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265097 CR44202 - http://flybase.org/reports/FBgn0265097 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44202, CR44202" - CR44202 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039265 CG11790 - http://flybase.org/reports/FBgn0039265 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 apoptotic cell clearance ; GO:0043277 | inferred from biological aspect of ancestor with PANTHER:PTN001053302 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 CG11790 IPR012336:Thioredoxin-like fold CG11790 11-Aug-17 DroID_v2017_08 "Drer\txndc5, Drer\dnajc10, Drer\txndc16, Drer\pdia6, Drer\erp27, Drer\pdia4" "Scer\MPD1, Scer\EPS1, Scer\MPD2" Cele\D2092.4 "Xtro\txndc16, Xtro\txndc5, Xtro\pdia6" "Mmus\Dnajc10, Mmus\Txndc16, Mmus\Pdia6, Mmus\Pdia5, Mmus\Erp27, Mmus\Txndc5" "Hsap\PDILT, Hsap\PDIA5, Hsap\TXNDC5, Hsap\TXNDC16, Hsap\DNAJC10, Hsap\ERP27, Hsap\PDIA6" "viable,fertile" FBgn0053233 CG33233 - http://flybase.org/reports/FBgn0053233 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000628500 "CG12036, CG33233" "IPR005829:Sugar transporter, conserved site, IPR027378:Cyclic nucleotide-regulated ion channel, N-terminal domain, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG33233 11-Aug-17 DroID_v2017_08 "Drer\slc22a21, Drer\slc22a7b.2, Drer\slc22a7b.1, Drer\slc22a13, Drer\LOC101884074, Drer\sv2ba, Drer\sv2bb, Drer\slc22a6l, Drer\LOC100334012, Drer\slc22a5, Drer\sv2a, Drer\oatx, Drer\sv2, Drer\slc22a7b.3, Drer\sv2c, Drer\zgc:175176, Drer\zmp:0000001102" "Scer\QDR1, Scer\YHK8, Scer\TPO2, Scer\TPO3, Scer\DTR1, Scer\QDR2, Scer\QDR3, Scer\FLR1, Scer\TPO1, Scer\GIT1, Scer\AQR1, Scer\GAL2" "Cele\F23F12.3, Cele\T12B3.2, Cele\C44C10.3, Cele\oat-1, Cele\K11D9.3, Cele\F23F12.13, Cele\svop-1" "Xtro\slc22a6, Xtro\sv2b" "Mmus\Slc22a6, Mmus\Slc22a19, Mmus\Sv2c, Mmus\Sv2a, Mmus\Slc22a23, Mmus\Slc22a8, Mmus\Slc22a30, Mmus\Slc22a27, Mmus\Slc22a26, Mmus\Slc22a7, Mmus\Slc22a22, Mmus\Slc22a14, Mmus\Slc22a2, Mmus\Svop, Mmus\Slc22a16, Mmus\Sv2b, Mmus\Slc22a28, Mmus\Slc22a29, Mmus\Slc22a4, Mmus\Slc22a20" "Hsap\SLC22A9, Hsap\SLC22A24, Hsap\SV2A, Hsap\SLC22A6, Hsap\SLC22A2, Hsap\SLC22A25, Hsap\SVOP, Hsap\SLC22A23, Hsap\SV2B, Hsap\SLC22A1, Hsap\SLC22A7, Hsap\SLC22A12, Hsap\SV2C, Hsap\SLC22A10, Hsap\SLC22A8, Hsap\SLC22A11" FBgn0037530 EMC1 ER Membrane protein Complex 1 http://flybase.org/reports/FBgn0037530 protein_coding_gene - protein folding in endoplasmic reticulum ; GO:0034975 | inferred from biological aspect of ancestor with PANTHER:PTN000491005 endomembrane system ; GO:0012505 | inferred from direct assay ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN000491005 "NEST:bs09f06, CG2943, EMC1" "IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR011678:ER membrane protein complex subunit 1, C-terminal, IPR026895:ER membrane protein complex subunit 1" CG2943 11-Aug-17 DroID_v2017_08 Drer\emc1 Scer\EMC1 Cele\emc-1 Xtro\emc1 Mmus\Emc1 Hsap\EMC1 viable FBgn0083004 snoRNA:Psi28S-1175b snoRNA:Psi28S-1175b http://flybase.org/reports/FBgn0083004 snoRNA_gene - - - "snoRNA:Psi28S-1175b, psi28s-1175b, CR34559" - CR34559 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058322 CG40322 - http://flybase.org/reports/FBgn0058322 protein_coding_gene - - - CG40322 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021922 l(2)k11241 lethal (2) k11241 http://flybase.org/reports/FBgn0021922 - gene - - - l(2)k11241 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004846 l(3)88Bd lethal (3) 88Bd http://flybase.org/reports/FBgn0004846 - gene - - - "l(3)M1, l(3)88Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000792 fs(1)de2 female sterile (1) defective eggs 2 http://flybase.org/reports/FBgn0000792 - gene - - - "de2, fs(1)de2" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "endochorion,dorsal appendage,chorion" FBgn0044332 9.35 9.35 http://flybase.org/reports/FBgn0044332 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available 9.35 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060636 l(3)S084507b lethal (3) S084507b http://flybase.org/reports/FBgn0060636 gene - - - "0845/07, l(3)S084507b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031977 baf barrier to autointegration factor http://flybase.org/reports/FBgn0031977 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004122 karyosome formation ; GO:0030717 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype inferred from genetic interaction with ball nucleoplasm ; GO:0005654 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay "anon-WO0172774.178, baf, CG7380, BAF, dBAF" "IPR004122:Barrier- to-autointegration factor, BAF" CG7380 11-Aug-17 DroID_v2017_08 "Drer\banf1, Drer\si:dkey-211g8.4" - Cele\baf-1 "Xtro\banf1, Xtro\baf-l" "Mmus\Banf2, Mmus\Banf1" "Hsap\BANF1, Hsap\BANF2" "lethal,recessive,neuroanatomy defective,female fertile,female sterile" "imaginal disc,embryonic/larval central nervous system,condensed nuclear chromosome,nuclear envelope,nuclear chromatin,karyosome" FBgn0046756 pncr017:3R putative noncoding RNA 017:3R http://flybase.org/reports/FBgn0046756 non_protein_coding_gene - - - "CR33945, BcDNA:SD10988, pncr017:3R" - CR33945 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051521 CG31521 - http://flybase.org/reports/FBgn0051521 protein_coding_gene - - - CG31521 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062657 EP3306 EP3306 http://flybase.org/reports/FBgn0062657 gene - - - "EP(3)3306, EP3306" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023052 l(1)3Ak lethal (1) 3Ak http://flybase.org/reports/FBgn0023052 - gene - - - "DCE-7, DCE-4, 1200D15a, l(1)3Ak" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052255 Gr64f Gustatory receptor 64f http://flybase.org/reports/FBgn0052255 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype "sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of sweet taste ; GO:0050916 | inferred from genetic interaction with Gr64d, Gr64e, Gr64c, Gr64b, Gr64a detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009318 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr64f, DmGr64f, CG14988, Gr64A3, CG32255, Dmel64f, Gr64, GR64f" IPR009318:Gustatory receptor CG32255 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,viable" FBgn0036756 cln3 cln3 http://flybase.org/reports/FBgn0036756 protein_coding_gene - response to oxidative stress ; GO:0006979 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype regulation of JNK cascade ; GO:0046328 | inferred from mutant phenotype "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003492, InterPro:IPR018460 late endosome ; GO:0005770 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay vesicle ; GO:0031982 | inferred from direct assay" "CG5582, cln3, CLN3" "IPR003492:Batten's disease protein Cln3, IPR020846:Major facilitator superfamily domain, IPR018460:Batten's disease protein Cln3, subgroup" CG5582 11-Aug-17 DroID_v2017_08 Drer\cln3 Scer\YHC3 "Cele\cln-3.3, Cele\cln-3.1, Cele\cln-3.2" Xtro\cln3 Mmus\Cln3 Hsap\CLN3 "fertile,viable,oxidative stress response defective,recessive,short lived,starvation stress response defective,female limited,visible,increased cell death,long lived" "eye,embryo | dorsal closure stage,wing disc,wing blade,wing margin,wing vein,ommatidium,interommatidial bristle" FBgn0250734 l(3)S001813 lethal (3) S001813 http://flybase.org/reports/FBgn0250734 gene - - - "l(3)S001813, l(3)s001813" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267781 CR46112 - http://flybase.org/reports/FBgn0267781 non_protein_coding_gene - - - CR46112 - CR46112 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015899 anon-P1609-I anon-P1609-I http://flybase.org/reports/FBgn0015899 - gene - - - anon-P1609-I - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000642 fch fragile chorion http://flybase.org/reports/FBgn0000642 - gene molecular_function ; GO:0003674 | no biological data available eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fch - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" chorion FBgn0039256 CG13647 - http://flybase.org/reports/FBgn0039256 protein_coding_gene - - - CG13647 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061034 l(3)S023941b lethal (3) S023941b http://flybase.org/reports/FBgn0061034 gene - - - "0239/41, l(3)S023941b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0021962 l(2)k10111 lethal (2) k10111 http://flybase.org/reports/FBgn0021962 - gene - - - l(2)k10111 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052288 tRNA:Cys-GCA-1-1 transfer RNA:Cysteine-GCA 1-1 http://flybase.org/reports/FBgn0052288 tRNA_gene UGC codon-amino acid adaptor activity ; GO:0033414 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033414 cytosol ; GO:0005829 | inferred by curator from GO:0033414 "CR32288, AE002584.trna14-CysGCA, tRNA:C:GCA:AE002584-c, chr3L.trna14-CysGCA, tRNA:Cys-GCA-1-1, tRNA:CR32288, tRNA-Cys-GCA-1-1, UGC" - CR32288 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026565 CG1315 - http://flybase.org/reports/FBgn0026565 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001518, InterPro:IPR018223 argininosuccinate synthase activity ; GO:0004055 | inferred from biological aspect of ancestor with PANTHER:PTN000172504" arginine biosynthetic process ; GO:0006526 | inferred from biological aspect of ancestor with PANTHER:PTN000172504 argininosuccinate metabolic process ; GO:0000053 | inferred from biological aspect of ancestor with PANTHER:PTN000172504 urea cycle ; GO:0000050 | inferred from biological aspect of ancestor with PANTHER:PTN000172504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000172504 "BG:DS00004.14, CG1315" "IPR001518:Argininosuccinate synthase, IPR023434:Argininosuccinate synthase, type 1 subfamily, IPR018223:Argininosuccinate synthase, conserved site, IPR024074:Argininosuccinate synthetase, catalytic/multimerisation domain body, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG1315 11-Aug-17 DroID_v2017_08 Drer\ass1 Scer\ARG1 - Xtro\ass1 Mmus\Ass1 Hsap\ASS1 "viable,fertile" FBgn0259352 C459 - http://flybase.org/reports/FBgn0259352 gene - - - C459 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0022375 Pt-15A Adult protein-15A http://flybase.org/reports/FBgn0022375 - gene - - - Pt-15A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028027 l(3)S103408 lethal (3) S103408 http://flybase.org/reports/FBgn0028027 gene - - - "1034/08, l(3)S103408" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0023015 l(3)S029910 lethal (3) S029910 http://flybase.org/reports/FBgn0023015 FBgn0028016 gene - - - "299/10, 1064/14, 1029/10, 0299/10, l(3)S106414, l(3)S029910" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027199 l(2)23Ea lethal (2) 23Ea http://flybase.org/reports/FBgn0027199 - gene - - - l(2)23Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037922 CG14711 - http://flybase.org/reports/FBgn0037922 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG14711 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG14711 11-Aug-17 DroID_v2017_08 "Drer\gzf1, Drer\bcl6ab, Drer\si:ch73-138e16.4, Drer\zgc:66443, Drer\si:ch211-113e8.10, Drer\mynn" "Scer\CMR3, Scer\STP4, Scer\STP3" "Cele\M03D4.4, Cele\hinf-1, Cele\klf-3, Cele\eor-1" - "Mmus\Zfp810, Mmus\Zfp91, Mmus\Zfp239, Mmus\Zfp787, Mmus\Rreb1, Mmus\Zfp771" "Hsap\ZNF561, Hsap\ZNF8, Hsap\ZFP91, Hsap\ZNF771, Hsap\ZNF787, Hsap\ZNF761, Hsap\RREB1, Hsap\ZNF560" FBgn0033549 mms4 Methyl methanesulfonate sensitivity 4 http://flybase.org/reports/FBgn0033549 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006166 crossover junction endodeoxyribonuclease activity ; GO:0008821 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001078409 double-strand break repair ; GO:0006302 | inferred from biological aspect of ancestor with PANTHER:PTN001078409 replication fork processing ; GO:0031297 | inferred from biological aspect of ancestor with PANTHER:PTN001078409 resolution of meiotic recombination intermediates ; GO:0000712 | inferred from biological aspect of ancestor with PANTHER:PTN001078409 intra-S DNA damage checkpoint ; GO:0031573 | inferred from biological aspect of ancestor with PANTHER:PTN001078409 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN001078409 Holliday junction resolvase complex ; GO:0048476 | inferred from biological aspect of ancestor with PANTHER:PTN001078409 "mms4, CG12936, EME1" "IPR006166:ERCC4 domain, IPR033310:Mms4/EME1/EME2" CG12936 11-Aug-17 DroID_v2017_08 "Drer\eme1, Drer\eme2" Scer\MMS4 - "Xtro\eme1, Xtro\eme2" "Mmus\Eme1, Mmus\Eme2" "Hsap\EME1, Hsap\EME2" viable FBgn0026369 Sara Smad anchor for receptor activation http://flybase.org/reports/FBgn0026369 FBgn0034630 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B stem cell fate determination ; GO:0048867 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype asymmetric stem cell division ; GO:0098722 | inferred from mutant phenotype early endosome ; GO:0005769 | inferred from direct assay "SARA, dSARA, sara, CG15667, Sara" "IPR000306:FYVE zinc finger, IPR011011:Zinc finger, FYVE/PHD-type, IPR017165:Zinc finger, FYVE-type, endofin, IPR017455:Zinc finger, FYVE-related, IPR024608:Smad anchor for receptor activation, Smad-binding domain, IPR022557:Domain of unknown function DUF3480, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15667 11-Aug-17 DroID_v2017_08 "Drer\zfyve9a, Drer\zfyve21, Drer\fyco1a, Drer\zfyve9b, Drer\plekhf2, Drer\zfyve16" "Scer\PIB1, Scer\PIB2, Scer\FAB1" "Cele\lst-2, Cele\ZK632.12, Cele\aka-1" "Xtro\plekhf2, Xtro\zfyve21" "Mmus\Zfyve21, Mmus\Zfyve16, Mmus\Zfyve9, Mmus\Fyco1" "Hsap\FYCO1, Hsap\PLEKHF2, Hsap\ZFYVE21, Hsap\ZFYVE9, Hsap\ZFYVE16" "neuroanatomy defective,lethal,recessive,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,increased cell death,visible,viable" "NMJ bouton | larval stage,wing vein,ectopic,posterior crossvein,wing disc,double row,triple row,wing margin,anterior compartment,posterior compartment,wing vein L5" FBgn0267213 CR45653 - http://flybase.org/reports/FBgn0267213 non_protein_coding_gene - - - CR45653 - CR45653 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066293 CheB42b Chemosensory protein B 42b http://flybase.org/reports/FBgn0066293 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CG15241, CG33351, CheB42b" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG33351 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035383 CPT2 Carnitine palmitoyltransferase 2 http://flybase.org/reports/FBgn0035383 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR000542" fatty acid beta-oxidation ; GO:0006635 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype ketone body biosynthetic process ; GO:0046951 | inferred from mutant phenotype - "CG2107, SD01848p, dCPT2, CPT2" IPR000542:Acyltransferase ChoActase/COT/CPT CG2107 11-Aug-17 DroID_v2017_08 Drer\cpt2 "Scer\YAT2, Scer\YAT1" Cele\cpt-2 Xtro\cpt2 Mmus\Cpt2 Hsap\CPT2 FBgn0040371 CG12470 - http://flybase.org/reports/FBgn0040371 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "EG:BACR37P7.5, NEST:bs17h08, NEST:bs07e10, CG12470" - CG12470 11-Aug-17 DroID_v2017_08 - - - - Mmus\Fos "Hsap\FOS, Hsap\NKX2-8" "viable,visible" trichogen cell FBgn0060709 l(3)S070310b lethal (3) S070310b http://flybase.org/reports/FBgn0060709 gene - - - "0703/10, l(3)S070310b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0023351 Di Dopachrome isomerase http://flybase.org/reports/FBgn0023351 - gene dopachrome isomerase activity ; GO:0004167 | inferred from direct assay - - "DI, Di" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038282 dpr9 defective proboscis extension response 9 http://flybase.org/reports/FBgn0038282 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 synapse organization ; GO:0050808 | inferred from expression pattern behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG31114, Dpr-9, CG12601, CT34680, CG14863, CG14862, BcDNA:GH01517, CG33485, dpr9, Dpr9" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain" CG33485 11-Aug-17 DroID_v2017_08 "Drer\LOC100333196, Drer\LOC101885444, Drer\si:ch211-264f5.6, Drer\si:dkey-65b12.12" - Cele\zig-8 "Xtro\obsl1, Xtro\nfasc" - - "hypoactive,conditional,chemical sensitive,viable" DRSC14986 E -0.247984611 -0.431636777 3.5418129 1.207681888 0.610142826 0.428325044 FBgn0014216 l(2)31Ca lethal (2) 31Ca http://flybase.org/reports/FBgn0014216 - gene - - - l(2)31Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027631 ms(1)294 ms(1)294 http://flybase.org/reports/FBgn0027631 - gene - - - ms(1)294 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,meiotic cell cycle defective" meiotic cell cycle | male FBgn0039002 CG17625 - http://flybase.org/reports/FBgn0039002 protein_coding_gene - - - CG17625 "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG17625 11-Aug-17 DroID_v2017_08 "Drer\inppl1a, Drer\sash1a, Drer\sash1b, Drer\samsn1b, Drer\sash3, Drer\samsn1a" - - Xtro\samsn1 "Mmus\Sash3, Mmus\Sash1, Mmus\Inppl1, Mmus\Samsn1, Mmus\Caskin2, Mmus\Samd5" "Hsap\SASH1, Hsap\INPPL1, Hsap\SAMSN1, Hsap\SAMD5, Hsap\SASH3, Hsap\CASKIN2" "viable,fertile" FBgn0020875 anon-M53 anon-M53 http://flybase.org/reports/FBgn0020875 - gene - - - "2-M53, anon-M53" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0003299 rue ruffled eye http://flybase.org/reports/FBgn0003299 - gene - - - "EdKs, rue" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive,visible" "eye,macrochaeta,heat sensitive" FBgn0041197 PH4alpha-RP prolyl-4-hydroxylase-a related protein http://flybase.org/reports/FBgn0041197 gene - - - "PHaRP, PH(II)a, PHa-RP, PH4alpha-RP" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000903 fs(1)M112 female sterile (1) M112 http://flybase.org/reports/FBgn0000903 - gene - - - "fs(1)M112, fs(1)m112" - - 11-Aug-17 DroID_v2017_08 - - - - - - "egg,ocellar bristle" FBgn0065854 l(2)SH0300 lethal (2) SH0300 http://flybase.org/reports/FBgn0065854 gene - - - "l(2)SH0300, l(2)SH2 0300" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069232 gl(2L)210-31 gl(2L)210-31 http://flybase.org/reports/FBgn0069232 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)210-31 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "filzkorper,germline clone,maternal effect,embryonic/first instar larval cuticle" FBgn0060640 l(3)S084210b lethal (3) S084210b http://flybase.org/reports/FBgn0060640 gene - - - "0842/10, l(3)S084210b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0005373 x2 x2 http://flybase.org/reports/FBgn0005373 - gene - - - x2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004986 Bridged Bridged http://flybase.org/reports/FBgn0004986 - gene - - - "Br, Bridged" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" "wing,wing vein,wing vein L4" FBgn0036750 CG6034 - http://flybase.org/reports/FBgn0036750 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" - CG6034 "IPR002937:Amine oxidase, IPR023753:FAD/NAD(P)-binding domain" CG6034 11-Aug-17 DroID_v2017_08 "Drer\paox1, Drer\si:dkey-275b16.2, Drer\smox, Drer\zgc:66484, Drer\kdm1a" Scer\FMS1 "Cele\spr-5, Cele\amx-3, Cele\hpo-15, Cele\amx-1" "Xtro\paox, Xtro\LOC100145496, Xtro\kdm1b, Xtro\smox" "Mmus\Paox, Mmus\Smox, Mmus\Kdm1b, Mmus\Kdm1a" "Hsap\PAOX, Hsap\SMOX, Hsap\KDM1B, Hsap\KDM1A" viable FBgn0010342 Map60 Microtubule-associated protein 60 http://flybase.org/reports/FBgn0010342 FBgn0015027 protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24478 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity centrosome ; GO:0005813 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay inferred from physical interaction with Cp190 "CP60, Cp60, CG1825, CP-60, DMAP60, DMAP-60, Map60, MAP60, DMAP 60" IPR006578:MADF domain CG1825 11-Aug-17 DroID_v2017_08 - - - - - - "viable,mitotic cell cycle defective" mitotic spindle | embryonic stage FBgn0001322 kno knobbyhead http://flybase.org/reports/FBgn0001322 - gene - - - kno - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male fertile,reduced,viable,male" "adult head,eye,occipital foramen" FBgn0033859 fand fandango http://flybase.org/reports/FBgn0033859 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 phagocytosis ; GO:0006909 | inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from mutant phenotype" Prp19 complex ; GO:0000974 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "fand, CG6197, XAB2, Xab2, Prp5" "IPR003107:HAT (Half-A-TPR) repeat, IPR011990:Tetratricopeptide-like helical domain" CG6197 11-Aug-17 DroID_v2017_08 Drer\xab2 Scer\SYF1 Cele\C50F2.3 Xtro\xab2 Mmus\Xab2 Hsap\XAB2 lethal DRSC06967 E -0.050016907 0.624100278 -0.551890458 1.523494889 -0.425418511 -0.750103459 FBgn0033623 CG13202 - http://flybase.org/reports/FBgn0033623 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with HGNC:32700 cilium movement ; GO:0003341 | inferred from sequence or structural similarity with HGNC:32700 cellular_component ; GO:0005575 | no biological data available CG13202 "IPR031733:Dynein attachment factor, N-terminal" CG13202 11-Aug-17 DroID_v2017_08 Drer\ccdc103 - - Xtro\ccdc103 Mmus\Ccdc103 Hsap\CCDC103 viable FBgn0020789 rABP50 ribosomal 'Alu-repeat' binding protein 50 http://flybase.org/reports/FBgn0020789 - gene - - - rABP50 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267672 CR46008 - http://flybase.org/reports/FBgn0267672 non_protein_coding_gene - - - CR46008 - CR46008 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030959 CG6961 - http://flybase.org/reports/FBgn0030959 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok - "cg6961, CG6961" IPR000504:RNA recognition motif domain CG6961 11-Aug-17 DroID_v2017_08 Drer\poldip3 Scer\YRA1 "Cele\aly-1, Cele\aly-2" Xtro\poldip3 Mmus\Poldip3 Hsap\POLDIP3 FBgn0041579 AttC Attacin-C http://flybase.org/reports/FBgn0041579 protein_coding_gene - defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern humoral immune response ; GO:0006959 | inferred from expression pattern antibacterial humoral response ; GO:0019731 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern defense response ; GO:0006952 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "AttC, CG4740, MPAC, DIM-16, Att, att, DIM 16, attC, att C, Attacin C, C" "IPR005520:Attacin, N-terminal, IPR005521:Attacin, C-terminal" CG4740 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002154 l(2)me lethal (2) meander http://flybase.org/reports/FBgn0002154 - gene - - - "lme, l(2)me" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval tracheal system,embryonic/larval salivary gland" FBgn0051467 CG31467 - http://flybase.org/reports/FBgn0051467 protein_coding_gene phosphatase binding ; GO:0019902 | inferred from electronic annotation with InterPro:IPR026142 negative regulation of phosphatase activity ; GO:0010923 | inferred from electronic annotation with InterPro:IPR026142 - "CG6471, CG31467" IPR026142:Protein phosphatase 1 regulatory subunit 36 CG31467 11-Aug-17 DroID_v2017_08 Drer\ppp1r36 - - - Mmus\Ppp1r36 Hsap\PPP1R36 viable FBgn0033031 CG8245 - http://flybase.org/reports/FBgn0033031 protein_coding_gene - - - CG8245 "IPR008547:Protein of unknown function DUF829, TMEM53, IPR029058:Alpha/Beta hydrolase fold" CG8245 11-Aug-17 DroID_v2017_08 Drer\tmem53 - "Cele\T10B11.5, Cele\C09B8.4, Cele\T24H10.4, Cele\T10B11.6" Xtro\tmem53 Mmus\Tmem53 "Hsap\NTPCR, Hsap\TMEM53" viable DRSC04901 I -0.498945991 -2.257045038 -0.774888193 0.95911407 0.528937501 -0.253535406 FBgn0065123 l(3)SH144 lethal (3) SH144 http://flybase.org/reports/FBgn0065123 gene - - - "l(3)SH144, l(2)SH3 144" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035889 mkg-p monkey king protein http://flybase.org/reports/FBgn0035889 protein_coding_gene nucleotidyltransferase activity ; GO:0016779 | inferred from electronic annotation with InterPro:IPR002934 - - "mkgr, mkg-r, CG7163, mkg, mkg-p" "IPR002934:Polymerase, nucleotidyl transferase domain" CG7163 11-Aug-17 DroID_v2017_08 "Drer\zcchc11, Drer\tut1, Drer\trpt1, Drer\mtpap, Drer\zcchc6, Drer\papd4" Scer\TPT1 "Cele\usip-1, Cele\F43H9.3, Cele\Y34F4.3, Cele\cid-1, Cele\F31C3.2, Cele\gld-2, Cele\pup-2, Cele\R07H5.11, Cele\T08B2.4, Cele\pup-3, Cele\F43E2.1, Cele\mut-2, Cele\C53A5.16" "Xtro\tut1, Xtro\trpt1, Xtro\zcchc11, Xtro\mtpap, Xtro\zcchc6, Xtro\papd4" "Mmus\Papd4, Mmus\Trpt1, Mmus\Zcchc11, Mmus\Mtpap, Mmus\Tut1, Mmus\Zcchc6" "Hsap\ZCCHC11, Hsap\ZCCHC6, Hsap\MTPAP, Hsap\TRPT1, Hsap\PAPD4, Hsap\TUT1" FBgn0016865 l(2)39ADc lethal (2) 39ADc http://flybase.org/reports/FBgn0016865 - gene - - - "K490, l(2)39ADc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037324 Orco Odorant receptor co-receptor http://flybase.org/reports/FBgn0037324 protein_coding_gene calcium-release channel activity ; GO:0015278 | inferred from direct assay calmodulin binding ; GO:0005516 | inferred from sequence model inferred from mutant phenotype protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Orco olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b odorant binding ; GO:0005549 | inferred from physical interaction with Or67a inferred from physical interaction with Or85b behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | non-traceable author statement protein heterooligomerization ; GO:0051291 | inferred from physical interaction with Or43a regulation of protein localization ; GO:0032880 | inferred from mutant phenotype response to pheromone ; GO:0019236 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from direct assay cilium ; GO:0005929 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a cilium ; GO:0005929 | colocalizes_with inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay "Or83b, orco, OR83b, 83b, DOR45, 83A.2, CG10609, A45, or83b, Orco, DOR83b, OR49, vainsA, OR83B, ORCO, DmelOrco, DmOrco, DmORCO" "IPR004117:Olfactory receptor, insect" CG10609 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,long lived,female,male,dominant,locomotor behavior defective,neurophysiology defective,chemosensitive behavior defective,viable,mating rhythm defective,behavior defective,hyperactive,conditional,hypoactive,chemical resistant,chemical sensitive" "antennal sense organ,olfactory receptor neuron,adult lateral horn type II neuron,antennal intermediate sensillum I2,embryonic/larval olfactory receptor neuron,adult olfactory receptor neuron" DRSC12358 K 0.522243793 0.068423385 0.303211691 -0.484643266 1.515488499 -0.486438237 FBgn0052057 dpr10 defective proboscis extension response 10 http://flybase.org/reports/FBgn0052057 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 neuron projection membrane ; GO:0032589 | inferred from direct assay "CG32057, Dpr-10, CG14159, CG14158, CT33762, BcDNA:RE37920, dpr10, Dpr10" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003598:Immunoglobulin subtype 2" CG32057 11-Aug-17 DroID_v2017_08 "Drer\kirrel3b, Drer\kirrel3a, Drer\ncam1b, Drer\dscama, Drer\kirrelb, Drer\LOC100333196, Drer\sdk1b, Drer\paplna, Drer\LOC101885725, Drer\si:ch211-163c2.2, Drer\lrit1a, Drer\si:dkey-65b12.12, Drer\kirrela, Drer\lrit3b, Drer\lrit3a, Drer\ush2a, Drer\LOC101885444, Drer\lrit1b, Drer\si:ch211-264f5.6, Drer\si:ch1073-459j12.1, Drer\igsf9a, Drer\itgb4, Drer\kirrel3l, Drer\sdk1a, Drer\igsf9bb" - Cele\zig-8 "Xtro\nfasc, Xtro\kirrel2, Xtro\papln, Xtro\igsf9b, Xtro\lrit3, Xtro\obsl1" "Mmus\Kirrel, Mmus\Igsf9b, Mmus\Papln, Mmus\Amica1, Mmus\Kirrel3, Mmus\Sdk1, Mmus\Lrit1, Mmus\Kirrel2, Mmus\Ptprq, Mmus\Lrit3" "Hsap\KIRREL3, Hsap\KIRREL2, Hsap\SDK1, Hsap\PAPLN, Hsap\LRIT1, Hsap\KIRREL, Hsap\IGSF9B, Hsap\LRIT3, Hsap\USH2A" viable FBgn0264739 CG43997 - http://flybase.org/reports/FBgn0264739 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43997, CG12433" - CG43997 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039106 CG10301 - http://flybase.org/reports/FBgn0039106 protein_coding_gene - - - CG10301 "IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG10301 11-Aug-17 DroID_v2017_08 "Drer\rlbp1a, Drer\rlbp1b, Drer\ttpa, Drer\sec14l8, Drer\ttpal, Drer\clvs2, Drer\sec14l7" "Scer\YKL091C, Scer\SFH5, Scer\SEC14" - "Xtro\sec14l1, Xtro\clvs2, Xtro\sec14l3, Xtro\ttpal, Xtro\ttpa, Xtro\mospd2, Xtro\rlbp1, Xtro\sec14l5, Xtro\clvs1" "Mmus\Sec14l4, Mmus\Clvs2, Mmus\Sec14l1, Mmus\Sec14l3, Mmus\Ttpal, Mmus\Clvs1, Mmus\Sec14l5, Mmus\Ttpa, Mmus\Rlbp1, Mmus\Sec14l2" "Hsap\RLBP1, Hsap\TTPAL, Hsap\SEC14L6, Hsap\SEC14L3, Hsap\SEC14L2, Hsap\SEC14L1, Hsap\SEC14L5, Hsap\CLVS2, Hsap\CLVS1, Hsap\TTPA, Hsap\SEC14L4" FBgn0263659 CR43650 - http://flybase.org/reports/FBgn0263659 non_protein_coding_gene - - - "CR43650, pri-mir-8" - CR43650 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015527 peng penguin http://flybase.org/reports/FBgn0015527 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000333308 regulation of translation ; GO:0006417 | inferred from biological aspect of ancestor with PANTHER:PTN000333308 apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000333308 "CG1685, peng, pen" "IPR001313:Pumilio RNA-binding repeat, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR012959:CPL domain, IPR033133:Pumilio homology domain" CG1685 11-Aug-17 DroID_v2017_08 Drer\im:7148292 Scer\PUF6 Cele\puf-12 Xtro\pum3 Mmus\Pum3 Hsap\PUM3 embryonic stage -- adult stage FBgn0051274 CG31274 - http://flybase.org/reports/FBgn0051274 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:LP05795, CG31274" "IPR032675:Leucine-rich repeat domain, L domain-like" CG31274 11-Aug-17 DroID_v2017_08 "Drer\c13h10orf11, Drer\LOC100331330" Scer\LEA1 Cele\T19D7.6 Xtro\c10orf11 Mmus\1700112E06Rik "Hsap\C10orf11, Hsap\DNAAF1" FBgn0034321 CG14502 - http://flybase.org/reports/FBgn0034321 protein_coding_gene - - - CG14502 IPR010512:Protein of unknown function DUF1091 CG14502 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265671 CR44478 - http://flybase.org/reports/FBgn0265671 non_protein_coding_gene - - - CR44478 - CR44478 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261016 clos closca http://flybase.org/reports/FBgn0261016 protein_coding_gene molecular_function ; GO:0003674 | no biological data available torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay "CG12927, CG12928, CG34364, CG1863, CG33479, closca, clos, CG42600" IPR009039:EAR CG42600 11-Aug-17 DroID_v2017_08 "Drer\col6a3, Drer\col5a1, Drer\col28a1a, Drer\col9a2, Drer\col27a1a, Drer\col11a1b, Drer\col1a1b, Drer\col5a2b, Drer\si:ch211-196i2.1, Drer\si:dkey-225n22.4, Drer\col5a2a, Drer\col4a2, Drer\tspearb, Drer\col16a1, Drer\col4a5, Drer\col2a1b, Drer\col12a1b, Drer\col1a1a, Drer\col14a1a, Drer\col2a1a, Drer\col9a1a, Drer\LOC101883924, Drer\wu:fc38h03, Drer\col6a2, Drer\col4a6, Drer\tspeara, Drer\LOC101884357, Drer\LOC100538221, Drer\si:dkey-61l1.4, Drer\col27a1b, Drer\col6a1, Drer\col1a2, Drer\col6a4a, Drer\col9a1b, Drer\col11a2, Drer\zgc:153049, Drer\col11a1a, Drer\col17a1b, Drer\col7a1l, Drer\si:ch211-106n13.3" - - "Xtro\col6a2, Xtro\col4a2, Xtro\col3a1, Xtro\col7a1, Xtro\col1a1, Xtro\col1a2, Xtro\col11a2, Xtro\LOC100486063, Xtro\col27a1, Xtro\col14a1, Xtro\col4a5, Xtro\col4a6, Xtro\col5a1, Xtro\col24a1, Xtro\tspear, Xtro\col4a1, Xtro\col2a1" "Mmus\Col9a3, Mmus\Col4a4, Mmus\Col3a1, Mmus\Col9a1, Mmus\Col16a1, Mmus\Col20a1, Mmus\Col23a1, Mmus\Col13a1, Mmus\Col4a5, Mmus\Col4a1, Mmus\Col22a1, Mmus\Col7a1, Mmus\Col4a6, Mmus\Col28a1, Mmus\Col17a1, Mmus\Col24a1, Mmus\Vwa1, Mmus\Vwa2, Mmus\Col6a3, Mmus\Col6a4, Mmus\Col1a1, Mmus\8030474K03Rik, Mmus\Tspear, Mmus\Col2a1, Mmus\Tnn, Mmus\Col6a6, Mmus\Col11a1, Mmus\Col19a1, Mmus\Col1a2, Mmus\Col6a1, Mmus\Col5a2, Mmus\Col27a1, Mmus\4933412E24Rik, Mmus\Col14a1, Mmus\Col5a1, Mmus\Col4a3, Mmus\Col25a1, Mmus\Col6a5, Mmus\Col5a3, Mmus\Col4a2, Mmus\Col11a2" "Hsap\COL17A1, Hsap\COL5A2, Hsap\COL23A1, Hsap\COL4A2, Hsap\COL2A1, Hsap\COL25A1, Hsap\COL4A5, Hsap\TSPEAR, Hsap\COL20A1, Hsap\COL4A4, Hsap\COL27A1, Hsap\COL9A2, Hsap\COL5A3, Hsap\VWA1, Hsap\COL3A1, Hsap\COL6A6, Hsap\COL4A3, Hsap\COL9A3, Hsap\COL6A5, Hsap\COLQ, Hsap\COL19A1, Hsap\COL4A6, Hsap\COL14A1, Hsap\COL24A1, Hsap\COL11A2, Hsap\COL1A1, Hsap\COL9A1, Hsap\COL4A1, Hsap\COL11A1, Hsap\COL6A3, Hsap\COL6A1, Hsap\VWA2, Hsap\COL22A1, Hsap\COL1A2, Hsap\COL16A1, Hsap\COL7A1, Hsap\COL5A1" FBgn0263020 CG43315 - http://flybase.org/reports/FBgn0263020 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43315, CG13169" - CG43315 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039344 CG4582 - http://flybase.org/reports/FBgn0039344 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available CG4582 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG4582 11-Aug-17 DroID_v2017_08 "Drer\LOC101884800, Drer\lipca, Drer\lipg, Drer\lipia, Drer\lipib, Drer\LOC100331214, Drer\lpl, Drer\pla1a" - - "Xtro\lpl, Xtro\lipg" "Mmus\Pnlip, Mmus\Pnliprp1, Mmus\Lpl, Mmus\Liph, Mmus\Lipg, Mmus\Pnliprp2, Mmus\Lipi, Mmus\Lipc, Mmus\Pla1a" "Hsap\LIPI, Hsap\PNLIPRP1, Hsap\LIPC, Hsap\PNLIP, Hsap\LPL, Hsap\PNLIPRP3, Hsap\PNLIPRP2, Hsap\LIPH, Hsap\LIPG, Hsap\PLA1A" viable FBgn0267051 CR45495 - http://flybase.org/reports/FBgn0267051 pseudogene_attribute - - - CR45495 - CR45495 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263050 CG43345 - http://flybase.org/reports/FBgn0263050 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001736 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43345, CG9243" "IPR001736:Phospholipase D/Transphosphatidylase, IPR032803:PLD-like domain" CG43345 11-Aug-17 DroID_v2017_08 "Drer\ndufaf2, Drer\LOC101885593, Drer\si:dkeyp-110e4.6, Drer\si:ch211-194e18.2, Drer\pld3" - "Cele\F09G2.8, Cele\E04F6.4, Cele\Y51A2D.13, Cele\Y116A8C.30, Cele\T05C3.6" Xtro\pld3 "Mmus\Pld4, Mmus\Pld5, Mmus\Pld3" "Hsap\NDUFAF2, Hsap\PLD5, Hsap\PLD3, Hsap\PLD4" embryonic/larval hemocyte | third instar larval stage FBgn0264366 CR43818 - http://flybase.org/reports/FBgn0264366 non_protein_coding_gene - - - CR43818 - CR43818 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034645 ND-B12 NADH dehydrogenase (ubiquinone) B12 subunit http://flybase.org/reports/FBgn0034645 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O43676 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O43676" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O43676 "anon-EST:Posey84, anon-EST:Posey47, CG10320, 10320, NB2M, ND-B12" IPR012576:NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 CG10320 11-Aug-17 DroID_v2017_08 Drer\ndufb3 - Cele\C18E9.4 Xtro\ndufb3 Mmus\Ndufb3 Hsap\NDUFB3 viable FBgn0065798 l(2)SH0413 lethal (2) SH0413 http://flybase.org/reports/FBgn0065798 gene - - - "l(2)SH0413, l(2)SH2 0413" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000626 eyh eyelisch http://flybase.org/reports/FBgn0000626 - gene - - - eyh - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0036460 CG5114 - http://flybase.org/reports/FBgn0036460 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000458182 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000458182 "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000458182" CG5114 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG5114 11-Aug-17 DroID_v2017_08 "Drer\aamp, Drer\nwd2" "Scer\RSA4, Scer\SQT1" "Cele\ZK430.7, Cele\Y111B2A.12" Xtro\aamp "Mmus\Aamp, Mmus\Nwd2" "Hsap\AAMP, Hsap\NWD2" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC10482 I -1.532952799 -0.944726995 0.221737895 -0.932078526 0.32366935 0.448327039 FBgn0013282 Jhbp-30 Juvenile hormone binding protein - 30kD http://flybase.org/reports/FBgn0013282 - gene - - - Jhbp-30 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042106 CG18754 - http://flybase.org/reports/FBgn0042106 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP61, CG18754" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain" CG18754 11-Aug-17 DroID_v2017_08 "Drer\f2, Drer\f9a, Drer\f10" - "Cele\try-3, Cele\try-1" - "Mmus\Prss54, Mmus\Klk1b9, Mmus\Proc" "Hsap\MASP2, Hsap\F2, Hsap\MASP1" viable DRSC15387 IE 2.700545122 1.018025415 2.126006364 1.209857632 0.091656376 0.072972571 FBgn0267133 CR45573 - http://flybase.org/reports/FBgn0267133 non_protein_coding_gene - - - CR45573 - CR45573 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035290 dsb debris buster http://flybase.org/reports/FBgn0035290 protein_coding_gene - adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype phagosome maturation ; GO:0090382 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 lysosome ; GO:0005764 | inferred from direct assay phagocytic vesicle ; GO:0045335 | inferred from direct assay "CG1887, dsb, ph" IPR002159:CD36 family CG1887 11-Aug-17 DroID_v2017_08 "Drer\LOC564077, Drer\scarb2, Drer\scarb1, Drer\cd36" - "Cele\scav-3, Cele\scav-6, Cele\scav-5, Cele\scav-4, Cele\scav-1, Cele\scav-2" "Xtro\scarb1, Xtro\scarb2, Xtro\cd36" "Mmus\Scarb1, Mmus\Cd36, Mmus\Scarb2" "Hsap\CD36, Hsap\SCARB1, Hsap\SCARB2" "viable,neuroanatomy defective,conditional,lethal - all die before end of embryonic stage" "dorsal multidendritic neuron ddaC | pupal stage,dorsal multidendritic neuron ddaC,conditional" FBgn0039251 Trf4-2 Topoisomerase related function 4-2 http://flybase.org/reports/FBgn0039251 protein_coding_gene DNA-directed DNA polymerase activity ; GO:0003887 | non-traceable author statement polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from sequence or structural similarity with SGD:S000005243 nuclear polyadenylation-dependent ncRNA catabolic process ; GO:0071046 | inferred from sequence or structural similarity with SGD:S000005243 sister chromatid cohesion ; GO:0007062 | non-traceable author statement nucleolus ; GO:0005730 | inferred from sequence or structural similarity with SGD:S000005243 "AAF56369, Trf4-2, DmTRF4-2, CG17462" "IPR002058:PAP/25A-associated, IPR002934:Polymerase, nucleotidyl transferase domain" CG17462 11-Aug-17 DroID_v2017_08 "Drer\papd7, Drer\papd5" "Scer\TRF5, Scer\PAP2" Cele\gld-4 Xtro\papd5 "Mmus\Papd5, Mmus\Papd7" "Hsap\PAPD5, Hsap\PAPD7" "viable,fertile" FBgn0035432 ZnT63C Zinc transporter 63C http://flybase.org/reports/FBgn0035432 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0010312 zinc ion transmembrane transporter activity ; GO:0005385 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype response to zinc ion ; GO:0010043 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 cellular zinc ion homeostasis ; GO:0006882 | inferred from mutant phenotype zinc II ion transmembrane transport ; GO:0071577 | inferred from genetic interaction with ZnT77C regulation of sequestering of zinc ion ; GO:0061088 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 zinc ion homeostasis ; GO:0055069 | inferred from genetic interaction with Zip42C.1 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002524 apical plasma membrane ; GO:0016324 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG17723, dZnT63C, ZnT63C, ZnT1, dZnT1, cg17723, dZNT63C" "IPR002524:Cation efflux protein, IPR027470:Cation efflux protein, cytoplasmic domain" CG17723 11-Aug-17 DroID_v2017_08 "Drer\slc30a2, Drer\slc30a7, Drer\slc30a1b, Drer\slc30a1a, Drer\slc30a5, Drer\slc30a10, Drer\slc30a4, Drer\LOC100002134, Drer\slc30a8" "Scer\ZRC1, Scer\COT1, Scer\ZRG17, Scer\MSC2" "Cele\cdf-1, Cele\ttm-1, Cele\cdf-2, Cele\Y105E8A.3" "Xtro\slc30a10, Xtro\slc30a7, Xtro\slc30a1, Xtro\slc30a5" "Mmus\Slc30a4, Mmus\Slc30a5, Mmus\Slc30a10, Mmus\Slc30a7, Mmus\Slc30a1, Mmus\Slc30a2" "Hsap\SLC30A4, Hsap\SLC30A5, Hsap\SLC30A2, Hsap\SLC30A7, Hsap\SLC30A10, Hsap\SLC30A1" "lethal - all die before end of larval stage,some die during larval stage,viable,fertile,some die during third instar larval stage,melanotic mass phenotype" melanotic mass DRSC21989 IE -2.056668053 -0.609320822 -3.064179068 0.258972772 0.220453203 -1.336939746 FBgn0266668 Exo84 Exocyst 84 http://flybase.org/reports/FBgn0266668 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype synaptic vesicle targeting ; GO:0016080 | non-traceable author statement neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity maintenance of epithelial cell apical/basal polarity ; GO:0045199 | inferred from mutant phenotype synaptic vesicle docking ; GO:0016081 | non-traceable author statement exocyst localization ; GO:0051601 | inferred from biological aspect of ancestor with PANTHER:PTN000484343 meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement exocyst assembly ; GO:0001927 | inferred from biological aspect of ancestor with PANTHER:PTN000484343 actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype exocyst ; GO:0000145 | non-traceable author statement exocyst ; GO:0000145 | inferred from sequence or structural similarity exocyst ; GO:0000145 | inferred from direct assay "exo84, Exo84, CG6095, onr, Exo84p, DExo84, anon-WO0153538.55" "IPR033961:Exocyst complex component Exo84, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR016159:Cullin repeat-like-containing domain, IPR032403:Exocyst component Exo84, C-terminal" CG6095 11-Aug-17 DroID_v2017_08 Drer\exoc8 Scer\EXO84 Cele\exoc-8 Xtro\exoc8 Mmus\Exoc8 Hsap\EXOC8 FBgn0060602 l(3)S091709 lethal (3) S091709 http://flybase.org/reports/FBgn0060602 gene - - - "0917/09, l(3)S091709" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083317 E(smoDN)1124 Enhancer of smoDN 1124 http://flybase.org/reports/FBgn0083317 gene - - - E(smoDN)1124 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016673 Khc::Ggal\Cam Khc::Ggal\Cam http://flybase.org/reports/FBgn0016673 - engineered_fusion_gene - - - "Khc::mammal\Cam, Khc::Ggal\Cam" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "dMP2 neuron,vMP2 neuron,MP1 neuron" FBgn0058383 CG40383 - http://flybase.org/reports/FBgn0058383 protein_coding_gene - - - CG40383 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051007 CG31007 - http://flybase.org/reports/FBgn0051007 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrion organization ; GO:0007005 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 lateral inhibition ; GO:0046331 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 CG31007 "IPR010625:CHCH, IPR009069:Cysteine alpha-hairpin motif superfamily" CG31007 11-Aug-17 DroID_v2017_08 "Drer\chchd2, Drer\chchd10" Scer\MIX17 Cele\har-1 "Xtro\gpat3, Xtro\chchd10" "Mmus\Chchd2, Mmus\Chchd10" "Hsap\CHCHD10, Hsap\CHCHD2" "partially lethal - majority die,visible" "chaeta,supernumerary" FBgn0010134 l(1)tsW5 lethal (1) tsW5 http://flybase.org/reports/FBgn0010134 - gene - - - l(1)tsW5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0000736 fs(1)A59 female sterile (1) A59 http://flybase.org/reports/FBgn0000736 - gene - - - fs(1)A59 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,female sterile soma-dependent" "egg,dorsal appendage" FBgn0013810 Dhc36C Dynein heavy chain at 36C http://flybase.org/reports/FBgn0013810 - protein_coding_gene "glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from electronic annotation with InterPro:IPR000447 ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000447 glycerol-3-phosphate metabolic process ; GO:0006072 | inferred from electronic annotation with InterPro:IPR000447 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR000447 inner dynein arm ; GO:0036156 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "CG5526, dhc, DHC, Dhc, Dhc36C, Dhc36c, DHC7A" "IPR000447:FAD-dependent glycerol-3-phosphate dehydrogenase, IPR004273:Dynein heavy chain domain, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain" CG5526 11-Aug-17 DroID_v2017_08 "Drer\dnah3, Drer\wu:fj30b09, Drer\dnah1, Drer\si:dkeyp-87a6.1, Drer\dnah7l, Drer\si:dkeyp-86b9.1, Drer\dync1h1, Drer\dnah9l, Drer\dnah7, Drer\dnah2, Drer\dnah12" Scer\DYN1 "Cele\che-3, Cele\dhc-1" "Xtro\dnah2, Xtro\dnah7, Xtro\dnah14" "Mmus\Dnah10, Mmus\Dnah2, Mmus\Dnah7c, Mmus\Dnah11, Mmus\Dnah1, Mmus\Dync1h1, Mmus\Dnah9, Mmus\Dnhd1, Mmus\Dync2h1, Mmus\Dnah14, Mmus\Dnah6, Mmus\Dnah7a, Mmus\Dnah3, Mmus\Dnah7b, Mmus\Dnah5, Mmus\Dnah12, Mmus\Dnah17, Mmus\Dnah8" "Hsap\DNAH14, Hsap\DNAH8, Hsap\DNAH5, Hsap\DNAH12, Hsap\DNAH3, Hsap\DYNC2H1, Hsap\DNAH2, Hsap\DNAH11, Hsap\DNAH6, Hsap\DNAH7, Hsap\DNAH1, Hsap\DYNC1H1, Hsap\CCDC88B, Hsap\DNAH9, Hsap\DNAH10, Hsap\DNHD1, Hsap\DNAH17" " adult stage | female , adult stage | male , adult stage , embryonic stage " testis

"viable,auditory perception defective,neurophysiology defective" FBgn0085594 CG41278 - http://flybase.org/reports/FBgn0085594 protein_coding_gene - - - CG41278 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264532 l(3)ffA - http://flybase.org/reports/FBgn0264532 gene - - - l(3)ffA - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0032365 CG14929 - http://flybase.org/reports/FBgn0032365 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32953, anon-WO0140519.184, CG14929" IPR026769:MICOS complex subunit Mic13 CG14929 11-Aug-17 DroID_v2017_08 Drer\si:dkey-78l4.14 - Cele\W04C9.2 - Mmus\2410015M20Rik Hsap\C19orf70 "viable,fertile" FBgn0051157 CG31157 - http://flybase.org/reports/FBgn0051157 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31157 IPR026749:Transmembrane protein 135 CG31157 11-Aug-17 DroID_v2017_08 - - Cele\tmem-135 - - Hsap\TMEM135 viable DRSC29159 EK 0.854052555 -0.528582131 2.092233396 -0.162225655 -1.518057481 -0.643127875 FBgn0038074 Gnmt Glycine N-methyltransferase http://flybase.org/reports/FBgn0038074 protein_coding_gene glycine N-methyltransferase activity ; GO:0017174 | inferred from electronic annotation with InterPro:IPR014369 S-adenosylmethionine catabolic process ; GO:0050843 | inferred from mutant phenotype sarcosine biosynthetic process ; GO:1901054 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype S-adenosylmethionine cycle ; GO:0033353 | inferred from mutant phenotype - "CG6188, Gnmt, gnmt" "IPR014369:Glycine/Sarcosine N-methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR025714:Methyltransferase domain" CG6188 11-Aug-17 DroID_v2017_08 Drer\gnmt - - - Mmus\Gnmt Hsap\GNMT "viable,starvation stress response defective" FBgn0026393 Or43b Odorant receptor 43b http://flybase.org/reports/FBgn0026393 - protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from direct assay olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from mutant phenotype odorant binding ; GO:0005549 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay sensory perception of smell ; GO:0007608 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | traceable author statement integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "43b, OR43b, DOR81, CG17853, AN7, 25A.1/43, DOR25A.1, Or25A.1, Or43b" "IPR004117:Olfactory receptor, insect" CG17853 11-Aug-17 DroID_v2017_08 - - - - - - adult stage sensory neuron &&of antennal segment 3

"viable,fertile,smell perception defective" sensillum basiconicum DRSC07486 K 1.126410134 -0.1854825 0.90930995 -0.090260564 1.987378467 0.992276455 FBgn0043053 Ivk\pol Ivk element pol http://flybase.org/reports/FBgn0043053 transposable_element_gene RNA-DNA hybrid ribonuclease activity ; GO:0004523 | inferred from electronic annotation with InterPro:IPR002156 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR020847 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR020847 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR020847 "You\pol, Ivk\pol" "IPR000477:Reverse transcriptase domain, IPR020847:AP endonuclease 1, binding site, IPR005135:Endonuclease/exonuclease/phosphatase, IPR012337:Ribonuclease H-like domain, IPR002156:Ribonuclease H domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002324 l(3)86Fc lethal (3) 86Fc http://flybase.org/reports/FBgn0002324 - gene - - - "l(3)S063512, l(3)ck3, l(3)86Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive" FBgn0259461 C790 - http://flybase.org/reports/FBgn0259461 gene - - - C790 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin,chaeta,ectopic" FBgn0261260 mgl Megalin http://flybase.org/reports/FBgn0261260 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG34339, CG15316, SOSIE, CG34352, CG12139, CT7830, anon-WO0140519.108, CG12654, LDLR, mgl, Megalin, CG42611, Dm CG34352" "IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR018097:EGF-like calcium-binding, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR013032:EGF-like, conserved site, IPR001881:EGF-like calcium-binding domain, IPR000742:EGF-like domain, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000033:LDLR class B repeat, IPR026823:Complement Clr-like EGF domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR009030:Growth factor receptor cysteine-rich domain" CG42611 11-Aug-17 DroID_v2017_08 "Drer\lrp1ba, Drer\lrp1ab, Drer\sorl1, Drer\ldlrad3, Drer\si:dkey-258f14.3, Drer\scospondin, Drer\LOC100536757, Drer\ldlra, Drer\lrp1aa, Drer\lrp8, Drer\lrp2a, Drer\lrp1bb, Drer\lrp2b" "Scer\APM1, Scer\APM3, Scer\APM2" Cele\lrp-1 "Xtro\lrp2, Xtro\sorl1, Xtro\lrp4, Xtro\lrp1" "Mmus\Lrp4, Mmus\Cd320, Mmus\Lrp1b, Mmus\Lrp1, Mmus\Lrp2, Mmus\Sspo, Mmus\Lrp3, Mmus\Sorl1" "Hsap\LRP1, Hsap\CD320, Hsap\LRP4, Hsap\LRP2, Hsap\SORL1, Hsap\LRP5L, Hsap\LRP1B, Hsap\LRP3" FBgn0034229 CG4847 - http://flybase.org/reports/FBgn0034229 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 cysteine-type peptidase activity ; GO:0008234 | inferred from sequence or structural similarity multicellular organism reproduction ; GO:0032504 | inferred from expression pattern proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 proteolysis ; GO:0006508 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | inferred from sequence model "BEST:GH19547, CG4847" "IPR025661:Cysteine peptidase, asparagine active site, IPR000169:Cysteine peptidase, cysteine active site, IPR000668:Peptidase C1A, papain C-terminal, IPR013128:Peptidase C1A, IPR013201:Cathepsin propeptide inhibitor domain (I29)" CG4847 11-Aug-17 DroID_v2017_08 "Drer\ctsll, Drer\ctso, Drer\ctslb, Drer\si:dkey-26g8.4, Drer\ctsla, Drer\si:dkey-239j18.2, Drer\LOC100536033, Drer\ctsz, Drer\wu:fa26c03, Drer\ctsk, Drer\si:dkey-239j18.3, Drer\MGC174155, Drer\zgc:110239, Drer\si:dkey-269i1.4, Drer\LOC100333521, Drer\MGC174857, Drer\ctss2.2, Drer\ctsh, Drer\zgc:174153, Drer\si:dkey-183k8.2, Drer\ctsba, Drer\si:dkey-228a15.1, Drer\ctss2.1, Drer\cts12, Drer\ctss1, Drer\zgc:103438, Drer\si:dkey-269i1.3, Drer\ctsc, Drer\ctsbb, Drer\zgc:174855, Drer\ctsl.1, Drer\si:dkey-267n13.1" - Cele\cpl-1 "Xtro\ctsv, Xtro\ctsz, Xtro\ctsw, Xtro\ctsb, Xtro\ctss, Xtro\ctsl, Xtro\LOC100490139, Xtro\ctsh, Xtro\LOC100498238, Xtro\ctsc" "Mmus\Ctss, Mmus\BC051665, Mmus\Ctsw, Mmus\Cts8, Mmus\Cts7, Mmus\Cts6, Mmus\Ctsk, Mmus\Ctsq, Mmus\Ctso, Mmus\Ctsll3, Mmus\Ctla2b, Mmus\Ctla2a, Mmus\4930486L24Rik, Mmus\Ctsz, Mmus\Cts3, Mmus\Ctsm, Mmus\Ctsr, Mmus\Ctsh, Mmus\Ctsl, Mmus\Ctsb, Mmus\Ctsc, Mmus\Ctsj" "Hsap\CTSC, Hsap\CTSZ, Hsap\CTSW, Hsap\CTSO, Hsap\CTSL, Hsap\CTSB, Hsap\CTSK, Hsap\CTSV, Hsap\CTSS, Hsap\CTSH" viable FBgn0262457 mir-1015 mir-1015 stem loop http://flybase.org/reports/FBgn0262457 miRNA_gene - - - "miR-1015, dme-mir-1015, mir-1015, CR43031" - CR43031 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028993 scro scarecrow http://flybase.org/reports/FBgn0028993 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with vnd "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with vnd inferred from sequence or structural similarity with MGI:MGI:108067 "scrou, CG17595, CG18452, CG17594, scro, Scro, mdcds_36132" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG17594 11-Aug-17 DroID_v2017_08 "Drer\nkx2.2b, Drer\nkx2.3, Drer\nkx2.1, Drer\nkx3.2, Drer\nkx2.4b, Drer\nkx3.3, Drer\nkx2.4a, Drer\nkx2.7, Drer\nkx2.2a, Drer\nkx3-1, Drer\nkx2.5" Scer\YOX1 "Cele\unc-30, Cele\ceh-13, Cele\ceh-22, Cele\ceh-28, Cele\dsc-1, Cele\ceh-24" "Xtro\nkx2-2, Xtro\nkx2-5, Xtro\nkx3-1, Xtro\nkx2-4, Xtro\nkx3-3, Xtro\nkx2-6, Xtro\nkx2-8, Xtro\nkx2-3, Xtro\nkx2-1, Xtro\nkx3-2" "Mmus\Nkx3-1, Mmus\Nkx2-1, Mmus\Nkx2-6, Mmus\Nkx3-2, Mmus\Nkx2-3, Mmus\Nkx2-2, Mmus\Nkx2-9, Mmus\Nkx2-4, Mmus\Nkx2-5" "Hsap\NKX2-8, Hsap\NKX2-6, Hsap\NKX3-1, Hsap\NKX2-2, Hsap\NKX2-5, Hsap\NKX2-4, Hsap\NKX2-1, Hsap\NKX2-3, Hsap\NKX3-2" neuroanatomy defective "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,ventral multidendritic neuron vdaB" FBgn0085450 Snoo Sno oncogene http://flybase.org/reports/FBgn0085450 protein_coding_gene SMAD binding ; GO:0046332 | inferred from biological aspect of ancestor with PANTHER:PTN000000299 negative regulation of cell differentiation ; GO:0045596 | inferred from biological aspect of ancestor with PANTHER:PTN000000299 neuron development ; GO:0048666 | inferred from mutant phenotype negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from genetic interaction with tkv inferred from genetic interaction with babo dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of decapentaplegic signaling pathway ; GO:0090099 | inferred from direct assay inferred from mutant phenotype inferred from genetic interaction with tkv inferred from genetic interaction with babo inferred from genetic interaction with Mad inferred from genetic interaction with Med inferred from genetic interaction with Smox negative regulation of BMP signaling pathway ; GO:0030514 | inferred from biological aspect of ancestor with PANTHER:PTN000000299 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Snoo, CG34421, CG7093, SnoA, SnoI, SnoN2, SnoN, dSki, DskiL, CG7233, dSno, l(2)SH1402, snoN, l(2)SH2 1402, dSnoN, Sno, dsnoN, dsno, snoo" "IPR009061:Putative DNA-binding domain, IPR003380:Transforming protein Ski, IPR010919:SAND domain-like, IPR014890:c-SKI SMAD4-binding domain, IPR023216:Transcription regulator SKI/SnoN" CG34421 11-Aug-17 DroID_v2017_08 "Drer\skia, Drer\skilb, Drer\skor1b, Drer\skib, Drer\skila" - - Xtro\skil "Mmus\Skor1, Mmus\Skor2, Mmus\Skil, Mmus\Ski" "Hsap\SKOR1, Hsap\SKI, Hsap\SKOR2, Hsap\SKIL" FBgn0014367 nok next-of-kin http://flybase.org/reports/FBgn0014367 - gene - - - nok - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023076 Clk Clock http://flybase.org/reports/FBgn0023076 - protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001067 DNA binding ; GO:0003677 | non-traceable author statement DNA binding ; GO:0003677 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with per inferred from physical interaction with tim protein binding ; GO:0005515 | inferred from physical interaction with nej protein heterodimerization activity ; GO:0046982 | non-traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with cyc RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from physical interaction with cyc protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:O61734" "behavioral response to cocaine ; GO:0048148 | non-traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay circadian rhythm ; GO:0007623 | traceable author statement circadian rhythm ; GO:0007623 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | traceable author statement locomotor rhythm ; GO:0045475 | inferred from mutant phenotype circadian regulation of gene expression ; GO:0032922 | inferred from mutant phenotype response to temperature stimulus ; GO:0009266 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | non-traceable author statement entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype eclosion rhythm ; GO:0008062 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from genetic interaction with UniProtKB:P07663 inferred from genetic interaction with UniProtKB:P49021 eclosion rhythm ; GO:0008062 | non-traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement locomotor rhythm ; GO:0045475 | non-traceable author statement behavioral response to cocaine ; GO:0048148 | traceable author statement circadian regulation of heart rate ; GO:0003053 | inferred from mutant phenotype rhythmic behavior ; GO:0007622 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | non-traceable author statement" transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR001067 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001067 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001067 nucleus ; GO:0005634 | non-traceable author statement "CLK, dCLK, dClock, dClk, clk, clock, dCLK/JRK, jrk, dCLOCK, Jrk, CLOCK, dClck, Jerk, PAS1, CG7391, Clk, dclk, bHLHe10" "IPR000014:PAS domain, IPR001067:Nuclear translocator, IPR001610:PAC motif, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG7391 11-Aug-17 DroID_v2017_08 "Drer\ncoa1, Drer\ncoa3, Drer\arntl1b, Drer\clockb, Drer\ncoa2, Drer\clocka, Drer\arntl1a, Drer\npas2" - Cele\hif-1 "Xtro\arntl, Xtro\clock, Xtro\pasd1" "Mmus\Npas2, Mmus\Clock, Mmus\Ncoa3, Mmus\Arntl2, Mmus\Arntl" "Hsap\NPAS2, Hsap\PASD1, Hsap\ARNTL2, Hsap\ARNTL, Hsap\CLOCK" "locomotor rhythm defective,viable,circadian rhythm defective,feeding behavior defective,recessive,semidominant,eclosion rhythm defective,sleep defective,visual behavior defective,dominant,behavior defective,circadian behavior defective,lethal" larval LN period neuron FBgn0034117 CG7997 - http://flybase.org/reports/FBgn0034117 protein_coding_gene alpha-galactosidase activity ; GO:0004557 | inferred from biological aspect of ancestor with PANTHER:PTN000155295 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000111, InterPro:IPR002241 glycoside catabolic process ; GO:0016139 | inferred from biological aspect of ancestor with PANTHER:PTN000155295" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000155295 "CT24026, CG7997" "IPR000111:Glycoside hydrolase family 27/36, conserved site, IPR002241:Glycoside hydrolase, family 27, IPR013785:Aldolase-type TIM barrel, IPR017853:Glycoside hydrolase superfamily" CG7997 11-Aug-17 DroID_v2017_08 "Drer\naga, Drer\gla" - Cele\gana-1 "Xtro\naga, Xtro\gla" "Mmus\Naga, Mmus\Gla" "Hsap\GLA, Hsap\NAGA" viable FBgn0085796 CR41539 - http://flybase.org/reports/FBgn0085796 rRNA_gene - - - CR41539 - CR41539 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039923 MED26 Mediator complex subunit 26 http://flybase.org/reports/FBgn0039923 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with UniProtKB:O95402 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype "polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay nuclear pericentric heterochromatin ; GO:0031618 | inferred from physical interaction with Su(var)205 nucleolus ; GO:0005730 | inferred from direct assay mediator complex ; GO:0016592 | inferred from sequence or structural similarity core mediator complex ; GO:0070847 | inferred from physical interaction with MED14, MED17 mediator complex ; GO:0016592 | inferred from sequence or structural similarity with UniProtKB:O95402" "Med26, Arc70, dARC70, CG1823, CG1793, MED26, ARC 70, med26" "IPR017923:Transcription factor IIS, N-terminal, IPR003617:Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type" CG1793 11-Aug-17 DroID_v2017_08 "Drer\tcea2, Drer\si:dkey-33g10.1, Drer\tcea3, Drer\crsp7, Drer\tceanc2" Scer\DST1 - "Xtro\tceanc, Xtro\med26, Xtro\tcea3, Xtro\tceanc2, Xtro\tcea1" "Mmus\Stra6l, Mmus\Tcea3, Mmus\Tceanc, Mmus\Tcea1, Mmus\Med26, Mmus\Tcea2, Mmus\Tceanc2" "Hsap\TCEA3, Hsap\TCEA2, Hsap\TCEA1, Hsap\TCEANC, Hsap\MED26, Hsap\TCEANC2, Hsap\CALR3" DRSC17147 IEK -2.335622624 -2.171686628 -1.086576825 -1.836937941 1.904944065 3.320861283 FBgn0014215 l(2)31Bc lethal (2) 31Bc http://flybase.org/reports/FBgn0014215 - gene - - - l(2)31Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085411 CG34382 - http://flybase.org/reports/FBgn0085411 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34382, CG14165, CG14166" IPR015943:WD40/YVTN repeat-like-containing domain CG34382 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010621 CCT5 Chaperonin containing TCP1 subunit 5 http://flybase.org/reports/FBgn0010621 FBgn0027913 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012718 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" protein folding ; GO:0006457 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 microtubule associated complex ; GO:0005875 | inferred from direct assay chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000144283 chaperonin-containing T-complex ; GO:0005832 | inferred from sequence or structural similarity "Cct5, l(2)06444, BcDNA.GM12270, CG8439, BcDNA:GM12270, cct5, CCT5, TCP-1epsilon, Tcp1-epsilon, TCP1-epsilon" "IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012718:T-complex protein 1, epsilon subunit, IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG8439 11-Aug-17 DroID_v2017_08 Drer\cct5 Scer\CCT5 Cele\cct-5 Xtro\cct5 Mmus\Cct5 Hsap\CCT5 "lethal,recessive,partially lethal - majority die,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0014032 Sptr Sepiapterin reductase http://flybase.org/reports/FBgn0014032 - protein_coding_gene sepiapterin reductase activity ; GO:0004757 | inferred from direct assay oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006393 tetrahydrobiopterin biosynthetic process ; GO:0006729 | inferred from electronic annotation with InterPro:IPR006393 - "CG12117, Sptr, sptr, SR" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR006393:Sepiapterin reductase, IPR016040:NAD(P)-binding domain" CG12117 11-Aug-17 DroID_v2017_08 "Drer\dhrs4, Drer\spra, Drer\sprb" "Scer\IRC24, Scer\YIR035C" "Cele\F02C12.2, Cele\C01G12.5, Cele\dhs-13" Xtro\spr "Mmus\Spr, Mmus\Dhrs2, Mmus\Dhrs4" "Hsap\SPR, Hsap\DHRS2, Hsap\DHRS4" "viable,fertile" FBgn0004229 l(3)93Bc lethal (3) 93Bc http://flybase.org/reports/FBgn0004229 - gene - - - "l(3)rlr1, rlr1, l(3)93Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041008 CG41132 - http://flybase.org/reports/FBgn0041008 protein_coding_gene - - - "CG12459, CG41132" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033645 CG13196 - http://flybase.org/reports/FBgn0033645 protein_coding_gene - cell morphogenesis ; GO:0000902 | inferred from sequence or structural similarity with dyl integral component of membrane ; GO:0016021 | inferred from sequence model CG13196 - CG13196 11-Aug-17 DroID_v2017_08 - - - - - - viable tracheal system | embryonic stage 16 FBgn0250740 l(3)S042302 lethal (3) S042302 http://flybase.org/reports/FBgn0250740 gene - - - "l(3)S042302, l(3)s042302" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024322 Mut181 Mutant-181 http://flybase.org/reports/FBgn0024322 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available Mut181 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084027 CG41466 - http://flybase.org/reports/FBgn0084027 protein_coding_gene - - - CG41466 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061028 l(3)S024639a lethal (3) S024639a http://flybase.org/reports/FBgn0061028 gene - - - "0246/39, l(3)S024639a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031616 CG11932 - http://flybase.org/reports/FBgn0031616 protein_coding_gene - - - CG11932 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023108 anon-10Az anon-10Az http://flybase.org/reports/FBgn0023108 - gene - - - "19, anon-10Az" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051550 CG31550 - http://flybase.org/reports/FBgn0051550 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:18643 RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR000061 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12168, CG12167, CG31550" "IPR000467:G-patch domain, IPR000061:SWAP/Surp, IPR011990:Tetratricopeptide-like helical domain" CG31550 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-152o7.1, Drer\sugp1" - - Xtro\sugp1 "Mmus\Sugp1, Mmus\Gabre, Mmus\Sugp2" "Hsap\SUGP2, Hsap\SUGP1" viable FBgn0024212 lw long wing http://flybase.org/reports/FBgn0024212 - gene - - - lw - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0051084 CR31084 - http://flybase.org/reports/FBgn0051084 non_protein_coding_gene - - - "BcDNA:RH74240, CR31084, CG31084" - CR31084 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037537 CG2767 - http://flybase.org/reports/FBgn0037537 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp" - CG2767 "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG2767 11-Aug-17 DroID_v2017_08 "Drer\zgc:56622, Drer\akr1b1, Drer\akr1a1b, Drer\zgc:110782, Drer\si:dkey-180p18.9, Drer\zgc:101765, Drer\kcnab2b, Drer\akr7a3, Drer\akr1a1a, Drer\zgc:110366" "Scer\YDL124W, Scer\GCY1, Scer\YJR096W, Scer\YPR1, Scer\GRE3, Scer\ARA1" "Cele\C07D8.5, Cele\F53F1.2, Cele\Y39G8B.2, Cele\Y39G8B.1, Cele\T08H10.1, Cele\C01G5.5, Cele\K07C5.2, Cele\C56G3.2, Cele\C07D8.6, Cele\F53F1.3, Cele\ZC443.1" "Xtro\LOC548351, Xtro\akr1c1, Xtro\akr7a2, Xtro\akr1a1, Xtro\akr1b1, Xtro\akr1c8p, Xtro\akr1d1, Xtro\akr1c2" "Mmus\Akr1a1, Mmus\Akr1c14, Mmus\Akr1e1, Mmus\Akr1d1, Mmus\Akr1c21, Mmus\Akr1c18, Mmus\Akr7a5, Mmus\Akr1c13, Mmus\Akr1c12, Mmus\Akr1b3, Mmus\Akr1cl, Mmus\Akr1b10, Mmus\Akr1b7, Mmus\Akr1c20, Mmus\Akr1b8, Mmus\Akr1c6, Mmus\Akr1c19" "Hsap\AKR1B1, Hsap\AKR1A1, Hsap\AKR1B10, Hsap\AKR7A3, Hsap\AKR7A2, Hsap\AKR1C2, Hsap\AKR1E2, Hsap\AKR1D1, Hsap\AKR1C3, Hsap\AKR1C1, Hsap\AKR1C4, Hsap\AKR1B15" FBgn0266168 CR44874 - http://flybase.org/reports/FBgn0266168 non_protein_coding_gene - - - CR44874 - CR44874 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037169 CG11404 - http://flybase.org/reports/FBgn0037169 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GH11730, CG11404" - CG11404 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265079 CR44190 - http://flybase.org/reports/FBgn0265079 non_protein_coding_gene - - - "CR44190, lincRNA.199" - CR44190 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024184 unc-4 unc-4 http://flybase.org/reports/FBgn0024184 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "Unc4, CG6269, Dunc-4, DPHD-1, unc-4" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG6269 11-Aug-17 DroID_v2017_08 "Drer\alx3, Drer\uncx4.1, Drer\alx4a, Drer\alx1, Drer\uncx, Drer\si:dkey-43p13.5, Drer\nobox, Drer\prrx1b" - "Cele\unc-4, Cele\dsc-1" "Xtro\uncx, Xtro\prrx1, Xtro\prrx2, Xtro\alx1, Xtro\alx4" "Mmus\Alx1, Mmus\Prrx2, Mmus\Alx3, Mmus\Nobox, Mmus\Alx4, Mmus\Uncx, Mmus\Prrx1" "Hsap\ALX4, Hsap\NOBOX, Hsap\UNCX, Hsap\ALX3, Hsap\ALX1, Hsap\PRRX1, Hsap\PRRX2" "neuroanatomy defective,viable,visible" "chaeta,supernumerary" DRSC22074 K -0.22356879 -0.145218772 0.638486919 0.684621217 -1.680339485 -1.32180471 FBgn0002718 mell melanized-like http://flybase.org/reports/FBgn0002718 - gene - - - mell - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "adult thorax,wing,eye,tergite" FBgn0266025 CR44790 - http://flybase.org/reports/FBgn0266025 non_protein_coding_gene - - - "CR44790, lincRNA.17" - CR44790 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060728 l(3)S067712b lethal (3) S067712b http://flybase.org/reports/FBgn0060728 gene - - - "0677/12, l(3)S067712b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022967 snRNPD-U snRNPD-U http://flybase.org/reports/FBgn0022967 - gene - - nucleus ; GO:0005634 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from direct assay "D[U], snRNPD-U" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030837 CG8661 - http://flybase.org/reports/FBgn0030837 protein_coding_gene - - - "BcDNA:LP01183, CG8661" - CG8661 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002189 l(3)63Ab lethal (3) 63Ab http://flybase.org/reports/FBgn0002189 - gene - - - l(3)63Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0036821 CG3961 - http://flybase.org/reports/FBgn0036821 protein_coding_gene long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from sequence or structural similarity with HGNC:3569 long-chain fatty acid metabolic process ; GO:0001676 | inferred from sequence or structural similarity with HGNC:3569 - CG3961 "IPR000873:AMP-dependent synthetase/ligase, IPR025110:AMP-binding enzyme C-terminal domain, IPR020845:AMP-binding, conserved site" CG3961 11-Aug-17 DroID_v2017_08 "Drer\acsl3a, Drer\acsl2, Drer\acsl5, Drer\acsl1a, Drer\acsl3b, Drer\acsl4b, Drer\acsl6, Drer\acsl4a, Drer\acsbg2, Drer\acsbg1, Drer\acsl1b" "Scer\FAA3, Scer\FAA2, Scer\FAA1, Scer\FAA4" "Cele\acs-17, Cele\acs-13, Cele\acs-18, Cele\acs-5, Cele\acs-15, Cele\acs-3, Cele\acs-4" "Xtro\acsbg1, Xtro\acsl4, Xtro\acsl6, Xtro\acsl1, Xtro\acsl5, Xtro\acsbg2" "Mmus\Acsl5, Mmus\Acsbg1, Mmus\Acsl4, Mmus\Acsbg2, Mmus\Acsl6, Mmus\Acsl1, Mmus\Acsl3, Mmus\1700061G19Rik" "Hsap\ACSL1, Hsap\ACSL6, Hsap\ACSL3, Hsap\ACSBG1, Hsap\ACSL4, Hsap\ACSBG2, Hsap\ACSL5" "viable,fertile" DRSC10391 IE -1.622428975 -0.143707811 2.315210167 0.302428544 -1.310459629 0.032454216 FBgn0025643 CG3588 - http://flybase.org/reports/FBgn0025643 - protein_coding_gene - - - "EG:100G7.6, CG3588" - CG3588 11-Aug-17 DroID_v2017_08 "Drer\enah, Drer\evla, Drer\evlb, Drer\vaspb, Drer\vaspa" - Cele\unc-34 - "Mmus\Enah, Mmus\Evl, Mmus\Vasp" "Hsap\EVL, Hsap\VASP, Hsap\ENAH" "viable,fertile" DRSC18473 K 0.532550617 0.405089508 0.290560623 0.27738661 1.129714892 -2.276060267 FBgn0034237 eIF3b eukaryotic translation initiation factor 3 subunit b http://flybase.org/reports/FBgn0034237 protein_coding_gene translation initiation factor binding ; GO:0031369 | inferred from electronic annotation with InterPro:IPR011400 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000362658 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VSS1 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with UniProtKB:P55884 regulation of translational initiation ; GO:0006446 | inferred from sequence or structural similarity with UniProtKB:P55884 translational initiation ; GO:0006413 | inferred from sequence or structural similarity ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000362658 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with UniProtKB:P55884 cytosol ; GO:0005829 | inferred from sequence or structural similarity eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity "cg4878, CG4878, eIF3-S9, eIF3-s9, eIF3 S9, eIF3b" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR000504:RNA recognition motif domain, IPR011400:Eukaryotic translation initiation factor 3 subunit B, IPR034363:eIF3B, RNA recognition motif, IPR013979:Translation initiation factor, beta propellor-like domain" CG4878 11-Aug-17 DroID_v2017_08 "Drer\eif3ba, Drer\eif3bb" Scer\PRT1 Cele\eif-3.B Xtro\eif3b Mmus\Eif3b Hsap\EIF3B "viable,lethal" DRSC06900 EK -1.126676941 -1.278403783 -3.041365565 -4.406169217 0.759147943 2.10670504 FBgn0037571 CG11694 - http://flybase.org/reports/FBgn0037571 protein_coding_gene molecular_function ; GO:0003674 | no biological data available developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 cellular_component ; GO:0005575 | no biological data available CG11694 IPR007999:Protein of unknown function DUF745 CG11694 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC24061 K -0.449894226 0.384366305 0.835273418 0.841928296 -1.568423904 0.330063119 FBgn0265362 CG44303 - http://flybase.org/reports/FBgn0265362 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44303, CG3184" - CG44303 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084012 CG41448 - http://flybase.org/reports/FBgn0084012 protein_coding_gene - - - CG41448 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002402 l(3)99Dc lethal (3) 99Dc http://flybase.org/reports/FBgn0002402 - gene - - - l(3)99Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0021930 l(2)k11038 lethal (2) k11038 http://flybase.org/reports/FBgn0021930 - gene - - - l(2)k11038 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028893 CG31819 - http://flybase.org/reports/FBgn0028893 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BG:DS02795.3, BcDNA:AT12868, CG31819" "IPR032675:Leucine-rich repeat domain, L domain-like" CG31819 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031668 CG31917 - http://flybase.org/reports/FBgn0031668 protein_coding_gene nucleosome binding ; GO:0031491 | inferred from biological aspect of ancestor with PANTHER:PTN000318090 histone deacetylase binding ; GO:0042826 | inferred from biological aspect of ancestor with PANTHER:PTN000318090 histone exchange ; GO:0043486 | inferred from biological aspect of ancestor with PANTHER:PTN000318090 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of histone deacetylation ; GO:0031063 | inferred from biological aspect of ancestor with PANTHER:PTN000318090 cytoplasm ; GO:0005737 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay Swr1 complex ; GO:0000812 | inferred from biological aspect of ancestor with PANTHER:PTN000318090 "CG31917, CG14038, BcDNA:RE52596, Dromel_CG31917_FBtr0079037_mORF, Dmp18" "IPR007529:Zinc finger, HIT-type" CG31917 11-Aug-17 DroID_v2017_08 Drer\znhit1 Scer\VPS71 Cele\zhit-1 Xtro\znhit1 Mmus\Znhit1 Hsap\ZNHIT1 DRSC02363 E 0.019076022 0.484132181 -3.067688777 -1.465305213 1.433021781 1.161602987 FBgn0267535 CR45875 - http://flybase.org/reports/FBgn0267535 non_protein_coding_gene - - - CR45875 - CR45875 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058296 CG40296 - http://flybase.org/reports/FBgn0058296 protein_coding_gene - - - CG40296 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028542 NimB4 Nimrod B4 http://flybase.org/reports/FBgn0028542 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with UniProtKB:Q1HAY7 extracellular region ; GO:0005576 | inferred from sequence model "BG:DS00180.8, CT37470, DS00180.8, CG16882, CG33115, NimB4, nimB4" IPR000742:EGF-like domain CG33115 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000000846, Drer\fgb, Drer\tnfaip6, Drer\fgl2b, Drer\megf6a, Drer\angptl4, Drer\LOC100007488, Drer\fibcd1, Drer\zgc:171687, Drer\si:ch1073-110a20.1, Drer\pear1, Drer\wu:fj11g02, Drer\si:zfos-2330d3.8, Drer\tnc, Drer\angptl1a, Drer\zgc:158328, Drer\fgg, Drer\dkk2, Drer\angptl5, Drer\tnr, Drer\angptl3, Drer\megf6b, Drer\scarf1, Drer\si:ch1073-110a20.2, Drer\si:ch211-157b11.8, Drer\angptl6, Drer\si:zfos-2330d3.3, Drer\angpt1, Drer\si:ch211-287a12.9, Drer\esm1, Drer\ccbe1, Drer\fgl2a, Drer\angptl2b, Drer\tnxba, Drer\megf11, Drer\angpt2b, Drer\fga, Drer\angptl2a, Drer\dkk1a, Drer\angpt4, Drer\si:ch1073-110a20.3, Drer\tnw, Drer\megf10, Drer\si:ch211-203k16.3, Drer\si:zfos-2330d3.1, Drer\zgc:194887, Drer\si:zfos-2330d3.6" - "Cele\K10D3.4, Cele\ZC504.1, Cele\T15B7.1, Cele\Y69H2.10, Cele\Y43C5A.2, Cele\W05B2.2, Cele\Y26D4A.12, Cele\ensh-1, Cele\C08G9.2, Cele\R09H10.5, Cele\Y34B4A.5, Cele\ZK1193.3, Cele\Y69H2.3, Cele\D1044.7, Cele\B0393.5" "Xtro\angpt1, Xtro\fgb, Xtro\LOC100491105, Xtro\fgg, Xtro\angptl5, Xtro\fcn1, Xtro\tnr, Xtro\tnn, Xtro\angptl2, Xtro\angptl3, Xtro\megf11, Xtro\LOC100497330, Xtro\angptl4, Xtro\stab2, Xtro\fga, Xtro\angpt4, Xtro\tnc, Xtro\tnfaip6, Xtro\fcn3, Xtro\fcn2, Xtro\tnxb, Xtro\fgl2, Xtro\mfap4, Xtro\LOC100488177, Xtro\fgl1, Xtro\fibcd1" "Mmus\Angptl4, Mmus\Esm1, Mmus\Fga, Mmus\Fibcd1, Mmus\Fgg, Mmus\Tnxb, Mmus\Tnr, Mmus\Scarf1, Mmus\Dkk2, Mmus\Fcna, Mmus\Tnn, Mmus\Fgl2, Mmus\Angptl7, Mmus\Tnc, Mmus\Angptl6, Mmus\Angptl3, Mmus\Megf6, Mmus\Angpt1, Mmus\Pear1, Mmus\Dkk3, Mmus\Fgb, Mmus\Fcnb, Mmus\Tnfaip6, Mmus\Fgl1, Mmus\Angpt2, Mmus\Dner, Mmus\Angpt4, Mmus\Egfem1, Mmus\Megf11, Mmus\Megf10, Mmus\Mfap4, Mmus\Angptl1, Mmus\Angptl2, Mmus\Stab1" "Hsap\TNFAIP6, Hsap\TNXB, Hsap\ANGPTL2, Hsap\SCARF1, Hsap\SCARF2, Hsap\PEAR1, Hsap\TNR, Hsap\ANGPTL1, Hsap\MEGF10, Hsap\MEGF11, Hsap\ANGPTL7, Hsap\ANGPT1, Hsap\ANGPT2, Hsap\FGL2, Hsap\FIBCD1, Hsap\FCN3, Hsap\TNN, Hsap\ANGPTL3, Hsap\ANGPTL4, Hsap\MEGF6, Hsap\FGL1, Hsap\ANGPTL6, Hsap\FGA, Hsap\FCN2, Hsap\DKK2, Hsap\FGG, Hsap\ANGPTL5, Hsap\ANGPT4, Hsap\TNC, Hsap\FGB" viable FBgn0002236 l(3)68Bc lethal (3) 68Bc http://flybase.org/reports/FBgn0002236 FBgn0002231 gene - - - "l(3)C557, I, l(3)I, l(3)68Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0051184 LSm3 Like Sm 3 http://flybase.org/reports/FBgn0051184 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000318821 "nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from electronic annotation with InterPro:IPR034105 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000318821 cytoplasmic mRNA processing body assembly ; GO:0033962 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000006434 inferred from sequence or structural similarity with protein_id:CAB45866 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" Lsm1-7-Pat1 complex ; GO:1990726 | inferred from biological aspect of ancestor with PANTHER:PTN000318821 U6 snRNP ; GO:0005688 | inferred from biological aspect of ancestor with PANTHER:PTN000318821 U6 snRNP ; GO:0005688 | inferred from sequence or structural similarity with SGD:S000006434 U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000318821 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000318821 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG5926, BcDNA:RE11655, LSm3, CG31184, Lsm3" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR034105:Sm-like protein Lsm3" CG31184 11-Aug-17 DroID_v2017_08 "Drer\lsm3, Drer\zgc:153119" Scer\LSM3 "Cele\lsm-3, Cele\K07A1.3" Xtro\lsm3 Mmus\Lsm3 "Hsap\LSM3, Hsap\C19orf54" FBgn0265186 CG44251 - http://flybase.org/reports/FBgn0265186 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3884, CG44251" "IPR024518:Domain of unknown function DUF3421, IPR006616:DM9 repeat" CG44251 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002061 l(2)40Ff lethal (2) 40Ff http://flybase.org/reports/FBgn0002061 - gene - - - "40Ff, l(2Lh)Ff, 56-15, GroupVII, l(2L)D, l(2)40Ff" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,recessive,partially lethal - majority die" FBgn0024721 Su(var)96B96D Su(var)96B96D http://flybase.org/reports/FBgn0024721 - gene - - - Su(var)96B96D - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020406 Mcc Mcc http://flybase.org/reports/FBgn0020406 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "DMCC, dMCC, Mcc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259579 B0741 - http://flybase.org/reports/FBgn0259579 gene - - - B0741 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta" FBgn0020776 tondo tondo http://flybase.org/reports/FBgn0020776 - gene - - - "ton, tondo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "follicle cell,egg,dorsal appendage" FBgn0263266 com3 - http://flybase.org/reports/FBgn0263266 gene - gonad development ; GO:0008406 | inferred from mutant phenotype digestive tract mesoderm development ; GO:0007502 | inferred from mutant phenotype - com3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "gonad,visceral mesoderm" FBgn0060880 l(3)S045305 lethal (3) S045305 http://flybase.org/reports/FBgn0060880 gene - - - "0453/05, l(3)S045305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040855 CG15223 - http://flybase.org/reports/FBgn0040855 protein_coding_gene - - - CG15223 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040871 CG12479 - http://flybase.org/reports/FBgn0040871 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000480690 "CG12479, Minos1a" IPR007512:Protein of unknown function DUF543 CG12479 11-Aug-17 DroID_v2017_08 Drer\minos1 Scer\MIC10 Cele\F54A3.5 - Mmus\Minos1 "Hsap\MINOS1, Hsap\MINOS1-NBL1" FBgn0019813 fs(2)80 fs(2)80 http://flybase.org/reports/FBgn0019813 - gene - - - fs(2)80 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263848 CG43709 - http://flybase.org/reports/FBgn0263848 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43709 - CG43709 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050044 s-cup stanley-cup http://flybase.org/reports/FBgn0050044 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13153, CG13152, s-cup, CG30044" - CG30044 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014000 Hf Helical Factor http://flybase.org/reports/FBgn0014000 FBgn0032837 protein_coding_gene - innate immune response ; GO:0045087 | inferred from expression pattern - "CG10658, Hf, DHF, dhf, Os9, GH21" - CG10658 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015472 l(2)45ABb lethal (2) 45ABb http://flybase.org/reports/FBgn0015472 - gene - - - l(2)45ABb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0262370 mir-7 mir-7 stem loop http://flybase.org/reports/FBgn0262370 miRNA_gene - "compound eye development ; GO:0048749 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with Dl negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from genetic interaction with hh inferred from genetic interaction with ci eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype inferred from genetic interaction with ttk negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with ttk regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype regulation of G1/S transition of mitotic cell cycle ; GO:2000045 | inferred from mutant phenotype" - "miR-7, mir-7, dme-mir-7, 7, MIR-7, CR42883, Mir-7, CR33042, mir7, miR7, pri-miR-7, dme-miR-7-5p, dme-miR-7" - CR42883 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage FBgn0013246 E(var)3-11 E(var)3-11 http://flybase.org/reports/FBgn0013246 - gene - - - "E-var(3)11, E(var)3-11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0028855 CG15282 - http://flybase.org/reports/FBgn0028855 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15282, BG:DS07721.3, DS07721.3, BcDNA:RE15191" - CG15282 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC23090 K -0.421693563 -0.773259803 0.102128613 -0.305178565 0.632044407 1.769610313 FBgn0033784 SCCRO3 Squamous cell carcinoma-related oncogene 3 http://flybase.org/reports/FBgn0033784 protein_coding_gene ubiquitin-like protein binding ; GO:0032182 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 cullin family protein binding ; GO:0097602 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 negative regulation of cell growth ; GO:0030308 | inferred from sequence or structural similarity with HGNC:28734 positive regulation of apoptotic process ; GO:0043065 | inferred from sequence or structural similarity with HGNC:28734 response to radiation ; GO:0009314 | inferred from biological aspect of ancestor with PANTHER:PTN000264574 positive regulation of ubiquitin-protein transferase activity ; GO:0051443 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 positive regulation of protein neddylation ; GO:2000436 | inferred from genetic interaction with SCCRO cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000264574 perinuclear region of cytoplasm ; GO:0048471 | inferred from sequence or structural similarity with HGNC:28734 ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 plasma membrane ; GO:0005886 | inferred from direct assay "CG13322, anon-WO0118547.137, dSCCRO3, SCCRO3" "IPR005176:Potentiating neddylation domain, IPR014764:Defective-in-cullin neddylation protein" CG13322 11-Aug-17 DroID_v2017_08 "Drer\dcun1d5, Drer\dcun1d2b, Drer\dcun1d3, Drer\dcun1d4, Drer\dcun1d1" Scer\DCN1 Cele\dcn-1 "Xtro\dcun1d3, Xtro\dcun1d2, Xtro\dcun1d5" "Mmus\Dcun1d4, Mmus\Dcun1d1, Mmus\Dcun1d2, Mmus\Dcun1d3, Mmus\Dcun1d5" "Hsap\DCUN1D5, Hsap\DCUN1D2, Hsap\DCUN1D4, Hsap\DCUN1D3, Hsap\DCUN1D1" viable FBgn0028009 l(3)S113208a lethal (3) S113208a http://flybase.org/reports/FBgn0028009 gene - - - "1132/8, 1132/08, l(3)S113208, l(3)S113208a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002398 l(3)96Fb lethal (3) 96Fb http://flybase.org/reports/FBgn0002398 - gene - - - "C2, l(3)C2, l(3)96Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025149 ms(2)A7 ms(2)A7 http://flybase.org/reports/FBgn0025149 - gene - - - ms(2)A7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0040658 CG13516 - http://flybase.org/reports/FBgn0040658 protein_coding_gene signal transducer activity ; GO:0004871 | inferred from sequence or structural similarity with HGNC:16841 signal transduction ; GO:0007165 | inferred from sequence or structural similarity with HGNC:16841 apoptotic process ; GO:0006915 | inferred from sequence or structural similarity with HGNC:13234 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:16841 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:16841 "BP1036, CG13516" IPR006629:LPS-induced tumour necrosis factor alpha factor CG13516 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-75b4.8, Drer\si:ch211-202h22.8, Drer\si:ch211-202h22.7, Drer\si:ch211-157c3.4, Drer\cdip1, Drer\litaf, Drer\si:ch211-202h22.9" - "Cele\Y87G2A.19, Cele\Y22D7AL.15, Cele\Y37D8A.8, Cele\B0348.2, Cele\Y40H7A.11, Cele\F36G3.3, Cele\F16F9.1, Cele\B0348.1, Cele\Y37D8A.6, Cele\Y37D8A.26, Cele\C08E8.1, Cele\Y87G2A.18" Xtro\litaf "Mmus\Litaf, Mmus\Cdip1" "Hsap\CDIP1, Hsap\LITAF" FBgn0063907 Neurodegeneration-13 Neurodegeneration 13 http://flybase.org/reports/FBgn0063907 gene - - - "ND13, Neurodegeneration-13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "central nervous system,eye" FBgn0005131 l(1)X20 lethal (1) X20 http://flybase.org/reports/FBgn0005131 - gene - - - l(1)X20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic epidermis,presumptive embryonic/larval central nervous system,gastrula embryo" FBgn0265447 CR44347 - http://flybase.org/reports/FBgn0265447 non_protein_coding_gene - - - CR44347 - CR44347 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034418 CG15118 - http://flybase.org/reports/FBgn0034418 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from direct assay "anon-EST:fe1H12, CG15118" "IPR002110:Ankyrin repeat, IPR003903:Ubiquitin interacting motif, IPR020683:Ankyrin repeat-containing domain, IPR021832:Ankyrin repeat domain-containing protein 13" CG15118 11-Aug-17 DroID_v2017_08 "Drer\ankrd13d, Drer\btr12, Drer\ankrd13b, Drer\ankrd13c, Drer\ankrd13a" - Cele\C18F10.7 "Xtro\ankrd13b, Xtro\ankrd13c, Xtro\ankrd13a" "Mmus\Ankrd13a, Mmus\Ankrd13c, Mmus\Ankrd13b, Mmus\Ankrd13d" "Hsap\ANKRD13B, Hsap\ANKRD13D, Hsap\ANKRD13C, Hsap\ANKRD13A" "viable,fertile" FBgn0001694 l(1)ESHS15 lethal (1) ESHS15 http://flybase.org/reports/FBgn0001694 - gene - - - l(1)ESHS15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267598 CR45936 - http://flybase.org/reports/FBgn0267598 non_protein_coding_gene - - - "CR45936, lincRNA.600" - CR45936 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039562 Gp93 Glycoprotein 93 http://flybase.org/reports/FBgn0039562 protein_coding_gene "unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001404, InterPro:IPR019805 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001404, InterPro:IPR019805" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001404, InterPro:IPR019805 response to stress ; GO:0006950 | inferred from electronic annotation with InterPro:IPR001404, InterPro:IPR019805 endodermal digestive tract morphogenesis ; GO:0061031 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype" endomembrane system ; GO:0012505 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CT17486, gp93, CG5520, p93, Gp93, Q9VAY2, GP93, HSP90B1, Hsp90, dGRP94" "IPR001404:Heat shock protein Hsp90 family, IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR019805:Heat shock protein Hsp90, conserved site, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR020575:Heat shock protein Hsp90, N-terminal" CG5520 11-Aug-17 DroID_v2017_08 "Drer\hsp90aa1.1, Drer\hsp90ab1, Drer\hsp90aa1.2, Drer\hsp90b1" "Scer\HSP82, Scer\HSC82" "Cele\enpl-1, Cele\daf-21" "Xtro\hsp90aa1.1, Xtro\hsp90ab1, Xtro\hsp90b1" "Mmus\Hsp90b1, Mmus\Hsp90ab1, Mmus\Hsp90aa1" "Hsap\HSP90AB1, Hsap\HSP90AA1, Hsap\HSP90B1" "viable,fertile,lethal - all die before end of larval stage,recessive,some die during third instar larval stage,developmental rate defective" "embryonic/larval cuprophilic cell,septate junction,embryonic/larval oenocyte,embryonic/larval fat body" DRSC15827 E -0.326613733 0.895974235 1.91538078 0.147114738 -0.124336195 0.087335277 FBgn0031724 CG18266 - http://flybase.org/reports/FBgn0031724 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.54, CG18266" - CG18266 11-Aug-17 DroID_v2017_08 "Drer\zgc:153293, Drer\LOC103909961" - - - Mmus\Ccdc34 Hsap\CCDC34 FBgn0005394 fs(2)lto4 female sterile (2) lto4 http://flybase.org/reports/FBgn0005394 "FBgn0000992, FBgn0004822" gene molecular_function ; GO:0003674 | no biological data available ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "fs(2)ltoQB3, fs(2)lo-E, fs(2)lto4" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0031653 Jon25Biii Jonah 25Biii http://flybase.org/reports/FBgn0031653 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 endopeptidase activity ; GO:0004175 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG8871, 25B, SP177, Jon25B, Jon25Biii, Jon25" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG8871 11-Aug-17 DroID_v2017_08 Drer\masp2 - - - "Mmus\C1s1, Mmus\Cela1, Mmus\C1s2" "Hsap\F9, Hsap\C1S, Hsap\PROC" viable DRSC25069 K -0.078577165 0.108902711 -0.504271305 0.137678745 -2.23709514 -0.745318083 FBgn0086679 p pink http://flybase.org/reports/FBgn0086679 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | inferred from genetic interaction with car, g, Rab32, or negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype eye pigment biosynthetic process ; GO:0006726 | inferred from mutant phenotype protein targeting to lysosome ; GO:0006622 | inferred from mutant phenotype" BLOC-2 complex ; GO:0031084 | inferred from sequence or structural similarity with HGNC:17022 cytoplasm ; GO:0005737 | inferred from direct assay "dHPS5, CG9770, snb, p, HPS5, NP_649810" IPR015943:WD40/YVTN repeat-like-containing domain CG9770 11-Aug-17 DroID_v2017_08 "Drer\hps5, Drer\tecpr2" - Cele\W09G3.6 "Xtro\hps5, Xtro\tecpr2" "Mmus\Tecpr2, Mmus\Hps5" "Hsap\TECPR2, Hsap\HPS5" FBgn0040075 rept reptin http://flybase.org/reports/FBgn0040075 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR010339 ATP-dependent 5'-3' DNA helicase activity ; GO:0043141 | inferred from electronic annotation with InterPro:IPR027238 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VH07 inferred from physical interaction with UniProtKB:Q9W4S7 transcription corepressor activity ; GO:0003714 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs chromatin remodeling ; GO:0006338 | inferred by curator from GO:0031011 histone acetylation ; GO:0016573 | inferred from direct assay ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype histone exchange ; GO:0043486 | inferred from direct assay regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype Ino80 complex ; GO:0031011 | inferred from direct assay PRC1 complex ; GO:0035102 | colocalizes_with inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont nucleus ; GO:0005634 | inferred from direct assay "Reptin, Tip48/Reptin, dReptin, CG9750, dRep, Tip48, rep, drep, l(3)06945, anon-WO0142479.1, rept, Rept, psg10, REPT, Q9V3K3_DROME, REP, dRUVBL2" "IPR003593:AAA+ ATPase domain, IPR010339:TIP49, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027238:RuvB-like" CG9750 11-Aug-17 DroID_v2017_08 "Drer\sccpdhb, Drer\ruvbl1, Drer\sccpdha, Drer\ruvbl2, Drer\zgc:174379" Scer\RVB2 "Cele\ruvb-2, Cele\ldp-1, Cele\ruvb-1" "Xtro\ruvbl2, Xtro\LOC100490002, Xtro\ruvbl1" "Mmus\Sccpdh, Mmus\Ruvbl1, Mmus\Ruvbl2" "Hsap\RUVBL2, Hsap\RUVBL1, Hsap\SCCPDH" "lethal,recessive,suppressor of variegation,dominant,non-suppressor of variegation,decreased cell number,somatic clone,developmental rate defective,cell autonomous,lethal - all die before end of larval stage,some die during larval stage,viable,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval midgut,leg,embryonic/larval salivary gland,embryonic/larval brain,somatic clone,eye,ommatidium,embryonic/larval neuroblast,ganglion mother cell" DRSC11388 IEK -2.702275932 -0.423170009 -0.586710865 -2.614957971 1.780186639 2.5063576 FBgn0267197 CR45637 - http://flybase.org/reports/FBgn0267197 non_protein_coding_gene - - - CR45637 - CR45637 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005453 l(1)v306 lethal (1) v306 http://flybase.org/reports/FBgn0005453 - gene - - - "l(1)306, l(1)v306" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022003 l(2)k09310 lethal (2) k09310 http://flybase.org/reports/FBgn0022003 - gene - - - l(2)k09310 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002131 l(2)K204 lethal (2) K204 http://flybase.org/reports/FBgn0002131 - gene - - - l(2)K204 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028490 CG31705 - http://flybase.org/reports/FBgn0028490 protein_coding_gene - - - "BcDNA:GH07269, CG6528, CG31705" IPR032086:Protein of unknown function DUF4813 CG31705 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC01991 IE 1.040508387 -4.324584369 -1.217924123 -2.931299195 -0.480927052 0.352499438 FBgn0039006 Cyp6d4 Cyp6d4 http://flybase.org/reports/FBgn0039006 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp" - "6d4, CG12800, Cyp6d4" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG12800 11-Aug-17 DroID_v2017_08 "Drer\tbxas1, Drer\cyp3c1, Drer\cyp3c4, Drer\cyp3c2, Drer\cyp3a65, Drer\cyp3c3" Scer\ERG11 "Cele\cyp-43A1, Cele\cyp-13A2, Cele\cyp-25A4, Cele\cyp-13B1, Cele\cyp-13A5, Cele\cyp-13A3, Cele\cyp-25A3, Cele\cyp-13A11, Cele\cyp-25A2, Cele\cyp-13B2, Cele\cyp-13A10, Cele\cyp-13A12, Cele\cyp-13A7, Cele\cyp-13A8, Cele\cyp-44A1, Cele\cyp-25A1, Cele\cyp-13A6, Cele\cyp-13A4, Cele\cyp-13A1, Cele\cyp-25A6" "Xtro\tbxas1, Xtro\cyp3a5, Xtro\cyp3a4, Xtro\LOC100494419" "Mmus\Cyp3a13, Mmus\Cyp3a59, Mmus\Tbxas1, Mmus\Cyp3a41a, Mmus\Cyp3a16, Mmus\Cyp3a44, Mmus\Cyp3a57, Mmus\Cyp3a11, Mmus\Cyp3a41b, Mmus\Cyp3a25" "Hsap\CYP3A43, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A5, Hsap\TBXAS1, Hsap\CYP3A4, Hsap\CYP3A7" viable FBgn0033141 CG12831 - http://flybase.org/reports/FBgn0033141 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG12831 IPR031883:Protein of unknown function DUF4763 CG12831 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267412 CG45765 - http://flybase.org/reports/FBgn0267412 protein_coding_gene - - - "CG45765, Mst77Y" - CG45765 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003039 patch patched of Bridges http://flybase.org/reports/FBgn0003039 - gene - - - patch - - 11-Aug-17 DroID_v2017_08 - - - - - - sternite FBgn0082167 pan::pygo pan::pygo http://flybase.org/reports/FBgn0082167 engineered_fusion_gene - - - pan::pygo - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/first instar larval cuticle,denticle" FBgn0266253 CR44948 - http://flybase.org/reports/FBgn0266253 non_protein_coding_gene - - - "CR44948, lincRNA.845" - CR44948 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053462 CG33462 - http://flybase.org/reports/FBgn0053462 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence or structural similarity with HGNC:2097 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular region ; GO:0005576 | inferred from sequence model "SP41, CG8215, CG30086, CG33462" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG33462 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.15, Drer\si:ch211-165b19.9, Drer\si:dkey-21e2.12, Drer\gzm3, Drer\LOC558805, Drer\si:ch211-165b19.5, Drer\si:dkey-21e2.7" - Cele\try-3 - "Mmus\Mcpt1, Mmus\Gzmg, Mmus\Gzmb, Mmus\Mcpt8, Mmus\Gzmc, Mmus\Cma2, Mmus\Gzmd, Mmus\Mcpt4, Mmus\Gzmf, Mmus\Ctsg, Mmus\Klk6, Mmus\Gzme, Mmus\Cma1, Mmus\Mcpt9" "Hsap\GZMH, Hsap\CMA1, Hsap\CTSG, Hsap\GZMB" viable DRSC22902 K -0.323571517 0.530967592 -0.041014595 -0.235753899 1.508322112 0.108144543 FBgn0083938 BG642163 BG642163 http://flybase.org/reports/FBgn0083938 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "CG34102, BG642163(1a3), BG642163" - CG34102 11-Aug-17 DroID_v2017_08 - - Cele\col-41 - - - "viable,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0038808 Srp14 Signal recognition particle protein 14 http://flybase.org/reports/FBgn0038808 protein_coding_gene "endoplasmic reticulum signal peptide binding ; GO:0030942 | inferred from electronic annotation with InterPro:IPR003210 7S RNA binding ; GO:0008312 | inferred from electronic annotation with InterPro:IPR003210, InterPro:IPR009018" "SRP-dependent cotranslational protein targeting to membrane ; GO:0006614 | inferred from electronic annotation with InterPro:IPR003210, InterPro:IPR009018 protein targeting to ER ; GO:0045047 | inferred from biological aspect of ancestor with PANTHER:PTN000245647" "signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from biological aspect of ancestor with PANTHER:PTN000245647" "CG5417, BcDNA:RE48595, Srp14" "IPR003210:Signal recognition particle, SRP14 subunit, IPR009018:Signal recognition particle, SRP9/SRP14 subunit" CG5417 11-Aug-17 DroID_v2017_08 Drer\srp14 Scer\SRP14 "Cele\F25G6.8, Cele\F25G6.9" Xtro\srp14 Mmus\Srp14 Hsap\SRP14 "lethal - all die before end of pupal stage,some die during pupal stage" "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0041735 l(3)65AEa lethal (3) 65AEa http://flybase.org/reports/FBgn0041735 gene - - - l(3)65AEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065800 l(2)SH0410 lethal (2) SH0410 http://flybase.org/reports/FBgn0065800 gene - - - "l(2)SH0410, l(2)SH2 0410" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024178 y3-9 y3-9 http://flybase.org/reports/FBgn0024178 - gene - - - y3-9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001019 fs(3)A10 female sterile (3) A10 http://flybase.org/reports/FBgn0001019 - gene - - - fs(3)A10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "ovary,oocyte" FBgn0001146 gs(2)M grandchildless M http://flybase.org/reports/FBgn0001146 - gene - - - gs(2)M - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,non-rescuable maternal effect,partially,recessive,heat sensitive,grandchildless" "gonad,heat sensitive,pole cell" FBgn0064175 l(2)C805 lethal (2) C805 http://flybase.org/reports/FBgn0064175 gene - - - l(2)C805 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005589 anon-alaD anon-alaD http://flybase.org/reports/FBgn0005589 FBgn0004553 repeat_region - - - "ALA-D, ala-D, ALA-repeat, anon-alaD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037462 sunz sungrazer http://flybase.org/reports/FBgn0037462 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" - - "CG15179, BcDNA:AT31060, sunz" "IPR018247:EF-Hand 1, calcium-binding site, IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG15179 11-Aug-17 DroID_v2017_08 "Drer\ppp3r1a, Drer\tescb, Drer\efcab1, Drer\tesca, Drer\chp1, Drer\ppp3r1b, Drer\chp2, Drer\LOC100536377" Scer\CNB1 - "Xtro\chp1, Xtro\efcab1, Xtro\cib1, Xtro\ppp3r1" "Mmus\Chp2, Mmus\Chp1, Mmus\Tesc, Mmus\Cib4, Mmus\Ppp3r2, Mmus\Cib1, Mmus\Ppp3r1, Mmus\1700109H08Rik, Mmus\Tescl, Mmus\Efcab1" "Hsap\CIB1, Hsap\CHP2, Hsap\CIB4, Hsap\EFCAB1, Hsap\TESC, Hsap\PPP3R1, Hsap\CHP1, Hsap\PPP3R2" FBgn0038693 unc79 uncoordinated 79 http://flybase.org/reports/FBgn0038693 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to anesthetic ; GO:0072347 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "anon-WO0172774.15, anon-WO0153538.74, DUNC79, CG5237, unc79, dunc79, UNC79, Dunc79" "IPR016024:Armadillo-type fold, IPR024855:UNC79, IPR011989:Armadillo-like helical" CG5237 11-Aug-17 DroID_v2017_08 Drer\LOC101883855 - Cele\unc-79 Xtro\unc79 Mmus\Unc79 Hsap\UNC79 "viable,fertile,circadian behavior defective,chemical sensitive,locomotor behavior defective" adult abdomen FBgn0260021 guantanamera guantanamera http://flybase.org/reports/FBgn0260021 gene - - - guantanamera - - 11-Aug-17 DroID_v2017_08 - - - - - - chorion | germline clone FBgn0038798 Or92a Odorant receptor 92a http://flybase.org/reports/FBgn0038798 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "92a, DOR111, 92E.1, CG17916, Or92a, OR 92a, Or92A" "IPR004117:Olfactory receptor, insect" CG17916 11-Aug-17 DroID_v2017_08 - - Cele\T11F8.1 - - - viable FBgn0010087 Su(Dl)D107 Suppressor of Delta D107 http://flybase.org/reports/FBgn0010087 - gene - - - Su(Dl)D107 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037143 CR7448 - http://flybase.org/reports/FBgn0037143 pseudogene_attribute - - - "CR7448, CG7448" - CR7448 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000777 fs(1)A1304 female sterile (1) A1304 http://flybase.org/reports/FBgn0000777 - gene - - - fs(1)A1304 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0036277 CG10418 - http://flybase.org/reports/FBgn0036277 protein_coding_gene RNA binding ; GO:0003723 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000352619 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:13940 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000122 inferred from sequence or structural similarity with protein_id:AAD56226 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000352619 U6 snRNP ; GO:0005688 | non-traceable author statement catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000000122 inferred from sequence or structural similarity with protein_id:AAD56226 U6 snRNP ; GO:0005688 | inferred from biological aspect of ancestor with PANTHER:PTN000352619 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000000122 inferred from sequence or structural similarity with protein_id:AAD56226 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000352619 Lsm1-7-Pat1 complex ; GO:1990726 | inferred from biological aspect of ancestor with PANTHER:PTN000352619 nucleus ; GO:0005634 | inferred by curator from GO:0000381 "BcDNA:GM14851, CG10418" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR016654:U6 snRNA-associated Sm-like protein LSm2" CG10418 11-Aug-17 DroID_v2017_08 Drer\smx5 Scer\LSM2 Cele\gut-2 Xtro\lsm2 Mmus\Lsm2 Hsap\LSM2 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0060761 l(3)S063309 lethal (3) S063309 http://flybase.org/reports/FBgn0060761 gene - - - "0633/09, l(3)S063309" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0037164 CG11438 - http://flybase.org/reports/FBgn0037164 protein_coding_gene phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000017950 phosphatidate phosphatase activity ; GO:0008195 | non-traceable author statement lipid phosphatase activity ; GO:0042577 | inferred from biological aspect of ancestor with PANTHER:PTN000807400 regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype phospholipid metabolic process ; GO:0006644 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 dephosphorylation ; GO:0016311 | non-traceable author statement phospholipid dephosphorylation ; GO:0046839 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 "Css1alpha, WUN-like, CG11438, LPP-like, PAP2" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG11438 11-Aug-17 DroID_v2017_08 "Drer\plppr3b, Drer\ppap2d, Drer\plpp2b, Drer\plppr5b, Drer\plppr1, Drer\plpp2a, Drer\plppr5a, Drer\plpp3, Drer\plpp1a, Drer\LOC794598, Drer\plppr2a, Drer\plppr2b, Drer\plppr3a, Drer\plppr4a" "Scer\LPP1, Scer\DPP1" "Cele\T06D8.3, Cele\F53C3.13, Cele\F13E6.5, Cele\T28D9.3" "Xtro\plppr5, Xtro\plpp2, Xtro\plpp1, Xtro\plpp3, Xtro\LOC100135382" "Mmus\Plppr2, Mmus\Plppr3, Mmus\Plppr1, Mmus\Plpp2, Mmus\Plppr4, Mmus\Plpp1, Mmus\Plpp3, Mmus\Plppr5" "Hsap\PLPPR4, Hsap\PLPPR3, Hsap\PLPPR2, Hsap\PLPP3, Hsap\PLPPR1, Hsap\PLPP1, Hsap\PLPP2, Hsap\PLPPR5" "planar polarity defective,visible" "ommatidium,wing vein" FBgn0060575 l(3)S095708 lethal (3) S095708 http://flybase.org/reports/FBgn0060575 gene - - - "0957/08, l(3)S095708" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264507 CR43906 - http://flybase.org/reports/FBgn0264507 non_protein_coding_gene - - - CR43906 - CR43906 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035673 CG6602 - http://flybase.org/reports/FBgn0035673 protein_coding_gene - - - CG6602 - CG6602 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060902 l(3)S043934b lethal (3) S043934b http://flybase.org/reports/FBgn0060902 gene - - - "0439/34, l(3)S043934b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263881 l(3)A57 - http://flybase.org/reports/FBgn0263881 gene - - - l(3)A57 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0031315 CG14341 - http://flybase.org/reports/FBgn0031315 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14341 - CG14341 11-Aug-17 DroID_v2017_08 Drer\mea1 - - Xtro\mea1 Mmus\Mea1 Hsap\MEA1 viable FBgn0259620 B0323 - http://flybase.org/reports/FBgn0259620 gene - - - B0323 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing vein,unguis,tarsal segment,antennal segment,leg,arista" FBgn0003522 std staroid http://flybase.org/reports/FBgn0003522 - gene - - - "std, Std, staroid" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female semi-sterile,heat sensitive,male sterile,viable,reduced,small body" "eye,macrochaeta,heat sensitive,wing,thorax,wing vein L4,wing vein L5" FBgn0004654 Pgd Phosphogluconate dehydrogenase http://flybase.org/reports/FBgn0004654 "FBgn0001395, FBgn0003073, FBgn0028299" protein_coding_gene "phosphogluconate dehydrogenase (decarboxylating) activity ; GO:0004616 | inferred from electronic annotation with InterPro:IPR006113, InterPro:IPR006114, InterPro:IPR006115, InterPro:IPR006184" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006113, InterPro:IPR006114, InterPro:IPR006115, InterPro:IPR006183, InterPro:IPR006184, InterPro:IPR008927, InterPro:IPR013328 pentose-phosphate shunt ; GO:0006098 | inferred from electronic annotation with InterPro:IPR006113, InterPro:IPR006114, InterPro:IPR006184 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" - "6PGDH, 6-Pgd, 6-PGD, CG3724, EG:87B1.4, 6-pgd, Pdg, 6Pgdh, l(1)G0385, 6Pgd, l(1)Pgd, 6PGD, PGD, l(1)2De, l(1)2Dc, l35, N1, l(1)A7, A7, l(1)Pgd-A, l(1)N3[90], l(1)N1, Pgd, pgd, 6pgdh" "IPR006113:6-phosphogluconate dehydrogenase, decarboxylating, IPR006114:6-phosphogluconate dehydrogenase, C-terminal, IPR006115:6-phosphogluconate dehydrogenase, NADP-binding, IPR006184:6-phosphogluconate-binding site, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR013328:6-phosphogluconate dehydrogenase, domain 2, IPR016040:NAD(P)-binding domain, IPR006183:6-phosphogluconate dehydrogenase" CG3724 11-Aug-17 DroID_v2017_08 Drer\pgd "Scer\GND2, Scer\GND1" Cele\T25B9.9 Xtro\pgd Mmus\Pgd Hsap\PGD adult stage "electrophoretic variant,partially lethal - majority die,recessive,female sterile,lethal,lethal - all die before end of larval stage,some die during larval stage,maternal effect,viable,fertile" "oocyte,ovariole,germline clone,nurse cell & nucleus | germ-line clone,egg chamber,maternal effect" FBgn0000207 bot botch http://flybase.org/reports/FBgn0000207 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bot - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,embryonic segment" FBgn0020392 Nmt N-myristoyl transferase http://flybase.org/reports/FBgn0020392 FBgn0011313 protein_coding_gene glycylpeptide N-tetradecanoyltransferase activity ; GO:0004379 | inferred from sequence or structural similarity with UniProtKB:P14743 inferred from direct assay glycylpeptide N-tetradecanoyltransferase activity ; GO:0004379 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype N-terminal protein myristoylation ; GO:0006499 | inferred from direct assay dorsal closure ; GO:0007391 | traceable author statement membrane ; GO:0016020 | inferred from direct assay "153290_at, dNMT, l(3)j1C7, Nmt1, l(3)j1c7, CG7436, Nmt, nmt" "IPR000903:Myristoyl-CoA:protein N-myristoyltransferase, IPR016181:Acyl-CoA N-acyltransferase, IPR022676:Myristoyl-CoA:protein N-myristoyltransferase, N-terminal, IPR022677:Myristoyl-CoA:protein N-myristoyltransferase, C-terminal, IPR022678:Myristoyl-CoA:protein N-myristoyltransferase, conserved site" CG7436 11-Aug-17 DroID_v2017_08 "Drer\nmt2, Drer\nmt1a, Drer\nmt1b" Scer\NMT1 Cele\nmt-1 "Xtro\nmt2, Xtro\nmt1" "Mmus\Nmt2, Mmus\Nmt1" "Hsap\NMT1, Hsap\NMT2" "lethal,recessive,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,partially lethal - majority die,visible" "denticle belt,dorsal closure embryo,filzkorper,extended germ band embryo,cephalopharyngeal skeleton,presumptive embryonic/larval central nervous system,ventral nerve cord,presumptive embryonic/larval digestive system,embryonic leading edge cell,embryonic epidermis,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC11236 K 0.338702056 1.245028188 0.373205055 0.093269533 3.63558672 0.406519213 FBgn0266434 CG45064 - http://flybase.org/reports/FBgn0266434 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45064, CG9517" IPR015943:WD40/YVTN repeat-like-containing domain CG45064 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022018 l(2)k09021 lethal (2) k09021 http://flybase.org/reports/FBgn0022018 - gene - - - l(2)k09021 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031768 CG12393 - http://flybase.org/reports/FBgn0031768 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with HGNC:26509 "endosome organization ; GO:0007032 | inferred from sequence or structural similarity with HGNC:26509 receptor recycling ; GO:0001881 | inferred from biological aspect of ancestor with PANTHER:PTN001113730 endosome organization ; GO:0007032 | inferred from biological aspect of ancestor with PANTHER:PTN001113730 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN001113730" trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN001113730 recycling endosome ; GO:0055037 | inferred from biological aspect of ancestor with PANTHER:PTN001113730 recycling endosome ; GO:0055037 | inferred from sequence or structural similarity with HGNC:26509 early endosome ; GO:0005769 | inferred from biological aspect of ancestor with PANTHER:PTN001113730 CG12393 "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG12393 11-Aug-17 DroID_v2017_08 "Drer\zgc:153733, Drer\plekhj1, Drer\si:ch211-193c2.2" - Cele\Y37D8A.25 "Xtro\fam109b, Xtro\plekhj1, Xtro\fam109a" "Mmus\Fam109a, Mmus\Fam109b, Mmus\Plekhj1" "Hsap\PLEKHJ1, Hsap\FAM109B, Hsap\FAM109A" FBgn0043548 anon-12Bb anon-12Bb http://flybase.org/reports/FBgn0043548 gene - - - "cDNA F5, anon-12Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267502 5.8SrRNA:CR45842 5.8S ribosomal RNA:CR45842 http://flybase.org/reports/FBgn0267502 rRNA_gene - - - "5.8SrRNA:CR45842, CR45842" - CR45842 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013240 E(var)212 E(var)212 http://flybase.org/reports/FBgn0013240 - gene - - - E(var)212 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0019967 Khc::nod Khc::nod http://flybase.org/reports/FBgn0019967 - engineered_fusion_gene - - - "Khc::nod, Nod, Nod-KHC, nod" - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0035515 CG14997 - http://flybase.org/reports/FBgn0035515 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 - "BcDNA:GH04863, CG14997" IPR023753:FAD/NAD(P)-binding domain CG14997 11-Aug-17 DroID_v2017_08 Drer\sqrdl - "Cele\Y9C9A.16, Cele\sqrd-1" Xtro\sqrdl Mmus\Sqrdl Hsap\SQRDL "viable,fertile" FBgn0041780 Ssl2 Strictosidine synthase-like 2 http://flybase.org/reports/FBgn0041780 protein_coding_gene "strictosidine synthase activity ; GO:0016844 | inferred from electronic annotation with InterPro:IPR004141, InterPro:IPR018119 hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from biological aspect of ancestor with PANTHER:PTN000046327" "biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004141, InterPro:IPR018119" endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000046327 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000046327 "DmSSl2, CG11833, SSl2, Ssl2" "IPR018119:Strictosidine synthase, conserved region, IPR011042:Six-bladed beta-propeller, TolB-like, IPR004141:Strictosidine synthase" CG11833 11-Aug-17 DroID_v2017_08 "Drer\apmap, Drer\zgc:194209" - "Cele\T12G3.4, Cele\F57C2.5, Cele\C08E8.2" "Xtro\apmap, Xtro\apmap" Mmus\Apmap Hsap\APMAP viable DRSC14395 I -1.756612997 0.362420891 0.07190766 -0.344443221 0.138166162 -1.360729845 FBgn0066303 CG33932 - http://flybase.org/reports/FBgn0066303 protein_coding_gene - - - "CG32530, CG12533, BcDNA:RE70209, CG32530-ORFB, CG33932" IPR019396:Transmembrane Fragile-X-F-associated protein CG33932 11-Aug-17 DroID_v2017_08 Drer\tmem203 - Cele\T07A9.12 Xtro\tmem203 Mmus\Tmem203 Hsap\TMEM203 FBgn0052515 CG32515 - http://flybase.org/reports/FBgn0052515 protein_coding_gene - - - CG32515 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085784 CR41379 - http://flybase.org/reports/FBgn0085784 pseudogene_attribute - - - CR41379 - CR41379 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034560 CG9235 - http://flybase.org/reports/FBgn0034560 protein_coding_gene - - - CG9235 "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class" CG9235 11-Aug-17 DroID_v2017_08 "Drer\ptprga, Drer\ca9, Drer\cahz, Drer\ca15c, Drer\ca4b, Drer\ca16b, Drer\ca15b, Drer\ca10a, Drer\ca2, Drer\car15, Drer\zgc:153760, Drer\ca4c, Drer\ca6, Drer\ca14, Drer\ca4a, Drer\ca5a, Drer\ca15a, Drer\ca8, Drer\ca12, Drer\ca10b, Drer\ca7" - "Cele\cah-5, Cele\F59A2.5, Cele\cah-3" "Xtro\ca10, Xtro\ca12, Xtro\ca6, Xtro\ca1, Xtro\ca11, Xtro\ca4, Xtro\ca8, Xtro\LOC779564, Xtro\ca3, Xtro\ca5b, Xtro\ca14, Xtro\ca2, Xtro\ca7" "Mmus\Car5a, Mmus\Car14, Mmus\Car2, Mmus\Car12, Mmus\Car6, Mmus\Car1, Mmus\Car7, Mmus\Car11, Mmus\Car13, Mmus\Car15, Mmus\Car10, Mmus\Car3, Mmus\Ptprg, Mmus\Car4, Mmus\Car9, Mmus\Car5b, Mmus\Car8" "Hsap\CA11, Hsap\CA9, Hsap\CA5B, Hsap\CA8, Hsap\CA5A, Hsap\CA10, Hsap\CA1, Hsap\CA12, Hsap\CA4, Hsap\CA2, Hsap\CA7, Hsap\CA14, Hsap\CA3, Hsap\CA6, Hsap\PTPRG, Hsap\CA13" FBgn0016708 Reg-13 Rhythmically expressed gene 13 http://flybase.org/reports/FBgn0016708 - gene - - - "Dreg-13, Reg-13" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , embryonic stage | late " adult head

FBgn0065974 iab6-1.as iab6-1.as http://flybase.org/reports/FBgn0065974 gene - - - "6-1 as, iab6-1.as" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001832 l(1)ts480 lethal (1) ts480 http://flybase.org/reports/FBgn0001832 - gene - - - l(1)ts480 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0060860 l(3)S047719 lethal (3) S047719 http://flybase.org/reports/FBgn0060860 gene - - - "0477/19, l(3)S047719" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0022752 anon-A1 anon-A1 http://flybase.org/reports/FBgn0022752 - gene - - - "A1, anon-A1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264263 CR43763 - http://flybase.org/reports/FBgn0264263 non_protein_coding_gene - - - CR43763 - CR43763 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037419 Osi12 Osiris 12 http://flybase.org/reports/FBgn0037419 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi12, CG1154, osi12" IPR012464:Protein of unknown function DUF1676 CG1154 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015856 anon-13Aa anon-13Aa http://flybase.org/reports/FBgn0015856 - gene - - - "TS13, anon-13Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029947 CG1999 - http://flybase.org/reports/FBgn0029947 protein_coding_gene - - - "anon-WO0140519.160, CG1999" IPR015943:WD40/YVTN repeat-like-containing domain CG1999 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037223 TwdlU TweedleU http://flybase.org/reports/FBgn0037223 pseudogene_attribute - - - "CG14638, TwdlU, CR14638" - CR14638 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260306 GSd214 - http://flybase.org/reports/FBgn0260306 gene - - - GSd214 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0083985 CG34149 - http://flybase.org/reports/FBgn0083985 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12757, CG34149" IPR004210:BESS motif CG34149 11-Aug-17 DroID_v2017_08 "Drer\gpd1b, Drer\gpd1l, Drer\gpd1c, Drer\gpd1a" "Scer\GPD1, Scer\GPD2" "Cele\gpdh-2, Cele\gpdh-1" - "Mmus\Gpd1l, Mmus\Gpd1" "Hsap\GPD1L, Hsap\GPD1" FBgn0053995 CG33995 - http://flybase.org/reports/FBgn0053995 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG33995, Dromel_CG31919_FBtr0079006_uORF" - CG33995 11-Aug-17 DroID_v2017_08 Drer\ankrd39 - - - Mmus\Ankrd39 - FBgn0262840 CG43204 - http://flybase.org/reports/FBgn0262840 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43204, chr2R_8318110_8318385.0" - CG43204 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022301 l(1)L62.4 lethal (1) L62.4 http://flybase.org/reports/FBgn0022301 - gene - - - "L62.4, l(1)L62.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013680 mt:ND2 mitochondrial NADH-ubiquinone oxidoreductase chain 2 http://flybase.org/reports/FBgn0013680 FBgn0002867 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR003917, InterPro:IPR010933" "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from electronic annotation with InterPro:IPR003917, InterPro:IPR010933" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from mutant phenotype "CG34063, ND2, URF2, mt:ND2, nd2, nad2" "IPR001750:NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit, IPR003917:NADH:ubiquinone oxidoreductase, chain 2, IPR010933:NADH dehydrogenase subunit 2, C-terminal" CG34063 11-Aug-17 DroID_v2017_08 Drer\ND2 - Cele\ND2 Xtro\ND2 Mmus\ND2 "Hsap\ND5, Hsap\ND2" FBgn0267640 CR45978 - http://flybase.org/reports/FBgn0267640 non_protein_coding_gene - - - "CR45978, lincRNA.556" - CR45978 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052602 Muc12Ea Mucin 12Ea http://flybase.org/reports/FBgn0052602 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern chorion ; GO:0042600 | inferred by curator from GO:0007304 extracellular matrix ; GO:0031012 | inferred from sequence model "CG5228, Muc12Ea, CG32602" - CG32602 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-125o16.4, Drer\otogl, Drer\asic2, Drer\si:ch1073-392o20.2, Drer\LOC799643, Drer\scospondin, Drer\vwf" "Scer\FLO5, Scer\YMR317W, Scer\HPF1, Scer\FLO11, Scer\MSB2, Scer\FLO9, Scer\PRM7, Scer\YIL169C, Scer\FLO1, Scer\FIG2, Scer\HKR1" "Cele\Y46B2A.3, Cele\F20C5.6, Cele\H02F09.3, Cele\dpy-6, Cele\clec-223, Cele\ZC178.2, Cele\H43E16.1, Cele\srap-1" - "Mmus\Muc6, Mmus\Muc4, Mmus\Sbsn, Mmus\Muc5b, Mmus\Vwf, Mmus\Muc2, Mmus\Sspo, Mmus\Muc5ac, Mmus\Tgoln1, Mmus\Champ1" "Hsap\OTOG, Hsap\MUC16, Hsap\MUC4, Hsap\MUC17, Hsap\MUC19, Hsap\SBSN, Hsap\MUC5B, Hsap\MUC2, Hsap\SSPO, Hsap\MUC6, Hsap\MUC1, Hsap\VWF, Hsap\TGOLN2, Hsap\CHAMP1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0027145 l(3)71DEb lethal (3) 71DEb http://flybase.org/reports/FBgn0027145 - gene - - - l(3)71DEb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041134 l(2)44Fh lethal (2) 44Fh http://flybase.org/reports/FBgn0041134 gene - - - l(2)44Fh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030625 CG5877 - http://flybase.org/reports/FBgn0030625 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013 RNA interference ; GO:0016246 | inferred from biological aspect of ancestor with PANTHER:PTN001003642 chromatin silencing by small RNA ; GO:0031048 | inferred from biological aspect of ancestor with PANTHER:PTN001003642" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG5877 "IPR013633:siRNA-mediated silencing protein NRDE-2, IPR011990:Tetratricopeptide-like helical domain" CG5877 11-Aug-17 DroID_v2017_08 Drer\nrde2 - Cele\nrde-2 Xtro\nrde2 Mmus\Nrde2 Hsap\NRDE2 "viable,fertile,visible" trichogen cell FBgn0011136 l(1)Q211 lethal (1) Q211 http://flybase.org/reports/FBgn0011136 FBgn0010210 gene - - - l(1)Q211 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005249 l(3)R260 lethal of Roberts 260 http://flybase.org/reports/FBgn0005249 - gene - - - "l(3)260, l(3)R260" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0015821 Su(var)2-S29 Su(var)2-S29 http://flybase.org/reports/FBgn0015821 - gene - - - Su(var)2-S29 - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant" pigment cell FBgn0085361 CG34332 - http://flybase.org/reports/FBgn0085361 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34332 - CG34332 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043032 l(2)42Cc lethal (2) 42Cc http://flybase.org/reports/FBgn0043032 gene - - - l(2)42Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058256 CR40256 - http://flybase.org/reports/FBgn0058256 non_protein_coding_gene - - - CR40256 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034423 tbrd-2 testis-specifically expressed bromodomain containing protein-2 http://flybase.org/reports/FBgn0034423 protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from direct assay nuclear body ; GO:0016604 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay "7229, CG7229, tbrd-2, tBRD-2" "IPR001487:Bromodomain, IPR018359:Bromodomain, conserved site, IPR027353:NET domain" CG7229 11-Aug-17 DroID_v2017_08 "Drer\brd2a, Drer\brdt, Drer\brd4, Drer\brd3a, Drer\brd2b, Drer\brd3b" "Scer\BDF2, Scer\SPT7, Scer\BDF1" "Cele\bet-1, Cele\baz-2, Cele\bet-2" "Xtro\brd2, Xtro\brd3, Xtro\brd4, Xtro\brdt" "Mmus\Brd2, Mmus\Baz1a, Mmus\Brd3, Mmus\Cecr2, Mmus\Brdt, Mmus\Brd4" "Hsap\CECR2, Hsap\BRDT, Hsap\BRD3, Hsap\BAZ1A, Hsap\BRD2, Hsap\BRD4" viable FBgn0273453 slpr::Tak1 - http://flybase.org/reports/FBgn0273453 engineered_fusion_gene - - - slpr::Tak1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031804 CG9500 - http://flybase.org/reports/FBgn0031804 protein_coding_gene - - - "CG9500, AAF52372, FBpp0078910" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG9500 11-Aug-17 DroID_v2017_08 "Drer\angptl1a, Drer\angptl5, Drer\fgg, Drer\si:dkeyp-51b7.3, Drer\si:zfos-2330d3.8, Drer\fgl2a, Drer\si:ch1073-110a20.2, Drer\angpt4, Drer\si:ch1073-110a20.1, Drer\si:zfos-2330d3.1, Drer\fgb, Drer\si:ch211-287a12.9, Drer\tnc, Drer\si:zfos-2330d3.6, Drer\zgc:171687, Drer\tnw, Drer\si:ch211-203k16.3, Drer\angpt2b, Drer\angptl2b, Drer\si:ch211-157b11.8, Drer\LOC100007488, Drer\zgc:173915, Drer\si:zfos-2330d3.3, Drer\fgl2b, Drer\si:ch1073-110a20.3, Drer\angptl6, Drer\angptl2a, Drer\angptl4, Drer\LOC555374, Drer\zgc:194887, Drer\wu:fj11g02, Drer\mfap4, Drer\fga, Drer\angpt1, Drer\zmp:0000000846, Drer\tnxba, Drer\angptl7, Drer\angpt2a, Drer\angptl3, Drer\tnr, Drer\fgl1, Drer\fibcd1" - "Cele\Y69H2.3, Cele\Y43C5A.2, Cele\W05B2.2, Cele\T15B7.1, Cele\Y69H2.10, Cele\ZC504.1, Cele\Y26D4A.12, Cele\K10D3.4, Cele\C08G9.2, Cele\ensh-1" "Xtro\angptl3, Xtro\fcn1, Xtro\fgl1, Xtro\angpt4, Xtro\fgl2, Xtro\fibcd1, Xtro\tnc, Xtro\tnxb, Xtro\fcn3, Xtro\LOC100491105, Xtro\angptl2, Xtro\angptl5, Xtro\LOC100497330, Xtro\tnr, Xtro\angptl4, Xtro\fga, Xtro\LOC100488177, Xtro\angpt1, Xtro\tnn, Xtro\fgg, Xtro\mfap4, Xtro\fgb, Xtro\fcn2, Xtro\angptl7" "Mmus\Angptl6, Mmus\Angptl7, Mmus\Angptl4, Mmus\Mfap4, Mmus\Fcnb, Mmus\Fcna, Mmus\Angptl2, Mmus\Angpt2, Mmus\Tnn, Mmus\Angptl1, Mmus\Angpt4, Mmus\Fga, Mmus\Fgb, Mmus\Fgg, Mmus\Tnc, Mmus\Angpt1, Mmus\Fgl2, Mmus\Tnxb, Mmus\Tnr, Mmus\Fgl1, Mmus\Fibcd1, Mmus\Angptl3" "Hsap\FGL2, Hsap\TNXB, Hsap\FIBCD1, Hsap\TNC, Hsap\ANGPTL3, Hsap\ANGPT1, Hsap\FCN3, Hsap\ANGPTL7, Hsap\ANGPT2, Hsap\FGG, Hsap\ANGPTL4, Hsap\ANGPTL1, Hsap\FGL1, Hsap\ANGPTL5, Hsap\TNN, Hsap\FGA, Hsap\ANGPTL2, Hsap\ANGPTL6, Hsap\MFAP4, Hsap\ANGPT4, Hsap\FCN2, Hsap\FCN1, Hsap\FGB, Hsap\TNR" FBgn0039634 alpha-Man-Ib alpha-Mannosidase class I b http://flybase.org/reports/FBgn0039634 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001382 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from biological aspect of ancestor with PANTHER:PTN000201533" encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype N-glycan processing ; GO:0006491 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000201534 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 "CG11874, alpha-Man-Ib, ORE-11, dMas-3, mas-3" IPR001382:Glycoside hydrolase family 47 CG11874 11-Aug-17 DroID_v2017_08 "Drer\man1a1, Drer\man1a2, Drer\man1b1a, Drer\man1b1b" "Scer\MNL2, Scer\MNS1" "Cele\mans-3, Cele\mans-1, Cele\mans-4, Cele\mans-2" "Xtro\man1c1, Xtro\man1a1, Xtro\man1a2, Xtro\man1b1" "Mmus\Man1c1, Mmus\Man1a2, Mmus\Man1a, Mmus\Man1b1, Mmus\Usf3" "Hsap\MAN1C1, Hsap\MAN1A1, Hsap\MAN1B1, Hsap\USF3, Hsap\MAN1A2" "viable,fertile,immune response defective" DRSC14418 E 0.417179824 0.23203302 3.029793783 0.301880176 0.149487648 0.106651063 FBgn0032083 CG9541 - http://flybase.org/reports/FBgn0032083 protein_coding_gene nucleobase-containing compound kinase activity ; GO:0019205 | inferred from electronic annotation with InterPro:IPR000850 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850 nucleobase-containing compound metabolic process ; GO:0006139 | inferred from electronic annotation with InterPro:IPR000850 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9541 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033690:Adenylate kinase, conserved site, IPR000850:Adenylate kinase/UMP-CMP kinase" CG9541 11-Aug-17 DroID_v2017_08 "Drer\ak5l, Drer\ak1, Drer\si:ch211-199m3.4, Drer\ak5" Scer\URA6 Cele\F13E6.2 "Xtro\ak1, Xtro\cmpk1" "Mmus\Ak5, Mmus\Cmpk1, Mmus\Ak1, Mmus\Ak8, Mmus\Ak9" "Hsap\AK5, Hsap\CMPK1, Hsap\AK1, Hsap\AK9" "viable,fertile" DRSC03257 K 0.772889337 0.123674671 0.36955136 0.60960049 -0.068620609 1.829189526 FBgn0066367 diana diana http://flybase.org/reports/FBgn0066367 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available diana - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,memory defective,chemical sensitive" FBgn0262713 ifm(2)RS6 - http://flybase.org/reports/FBgn0262713 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0000531 E103 E103 http://flybase.org/reports/FBgn0000531 - gene - - - "90Bre, E103" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266180 CR44886 - http://flybase.org/reports/FBgn0266180 non_protein_coding_gene - - - CR44886 - CR44886 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038909 CG6569 - http://flybase.org/reports/FBgn0038909 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6569 - CG6569 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266024 CR44789 - http://flybase.org/reports/FBgn0266024 non_protein_coding_gene - - - CR44789 - CR44789 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001653 l(1)ds5 lethal (1) discs small 5 http://flybase.org/reports/FBgn0001653 - gene - - - "l(1)d.sml.-5, l(1)ds5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0086900 Cpr65Ax1 Cuticular protein 65Ax1 http://flybase.org/reports/FBgn0086900 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr65Ax1, CG34270, CG18774" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG34270 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\2410137M14Rik, Mmus\H2-K1" - FBgn0267547 CR45887 - http://flybase.org/reports/FBgn0267547 non_protein_coding_gene - - - CR45887 - CR45887 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000101 apb apterblister http://flybase.org/reports/FBgn0000101 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available apb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,some die during immature adult stage" "wing,alimentary canal" FBgn0028669 Vha100-3 Vacuolar H[+] ATPase 100kD subunit 3 http://flybase.org/reports/FBgn0028669 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000005796" vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence or structural similarity with SGD:S000005796 "vacuolar proton-transporting V-type ATPase complex ; GO:0016471 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000005796 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000907964" "vha100-3, CG30329, BcDNA:AT03238, Vha100-3" "IPR002490:V-type ATPase, V0 complex, 116kDa subunit family, IPR026028:ATPase, V0 complex, subunit 116kDa, eukaryotic" CG30329 11-Aug-17 DroID_v2017_08 "Drer\atp6v0a2a, Drer\tcirg1b, Drer\atp6v0a1a, Drer\atp6v0a2b, Drer\tcirg1a, Drer\atp6v0a1b" "Scer\VPH1, Scer\STV1" "Cele\vha-7, Cele\vha-6, Cele\vha-5, Cele\unc-32" "Xtro\tcirg1, Xtro\atp6v0a2, Xtro\atp6v0a4, Xtro\atp6v0a1" "Mmus\Atp6v0a4, Mmus\Atp6v0a2, Mmus\Tcirg1, Mmus\Atp6v0a1" "Hsap\ATP6V0A1, Hsap\ATP6V0A2, Hsap\ATP6V0A4, Hsap\TCIRG1" viable FBgn0005126 l(1)J770 lethal (1) J770 http://flybase.org/reports/FBgn0005126 - gene - - - l(1)J770 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0036124 CG7839 - http://flybase.org/reports/FBgn0036124 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000248189 "anon-EST:fe2H6, CG7839" "IPR005612:CCAAT-binding factor, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG7839 11-Aug-17 DroID_v2017_08 Drer\cebpz Scer\MAK21 Cele\F23B12.7 Xtro\cebpz Mmus\Cebpz Hsap\CEBPZ "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0028480 CG17841 - http://flybase.org/reports/FBgn0028480 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006634 "BcDNA:GH12326, clone 2.12, anon-EST:Liang-2.12, CG17841" IPR006634:TRAM/LAG1/CLN8 homology domain CG17841 11-Aug-17 DroID_v2017_08 "Drer\tmem56b, Drer\fam57ba, Drer\si:dkey-10f21.4, Drer\fam57bb, Drer\fam57a, Drer\tmem56a, Drer\cln8" "Scer\YPR114W, Scer\TDA4" Cele\Y63D3A.8 "Xtro\fam57a, Xtro\tmem56, Xtro\tmem56.2" "Mmus\Tmem56, Mmus\Cln8, Mmus\Fam57b, Mmus\Fam57a" "Hsap\CLN8, Hsap\TMEM56, Hsap\FAM57A, Hsap\FAM57B" "viable,fertile,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039086 CG16732 - http://flybase.org/reports/FBgn0039086 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG16732 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG16732 11-Aug-17 DroID_v2017_08 "Drer\ugt1b5, Drer\ugt5d1, Drer\zgc:172315, Drer\ugt2b1, Drer\ugt5e1, Drer\ugt5a5, Drer\ugt5g1, Drer\ugt1b3, Drer\ugt2a2, Drer\ugt5b3, Drer\ugt8, Drer\ugt5b2, Drer\ugt5b1, Drer\ugt2b6, Drer\ugt1ab, Drer\ugt5a4, Drer\ugt2a6, Drer\ugt5b6, Drer\ugt2b5, Drer\ugt1b7, Drer\ugt2a5, Drer\ugt1b2, Drer\ugt1b4, Drer\ugt5c3, Drer\ugt5a2, Drer\ugt5c2, Drer\ugt5b4, Drer\ugt5a1, Drer\ugt2b3, Drer\ugt5f1, Drer\ugt5c1, Drer\ugt5g2" Scer\ATG26 "Cele\ugt-59, Cele\Y43D4A.2, Cele\ugt-24, Cele\ugt-5, Cele\ugt-46, Cele\ugt-48, Cele\ugt-54, Cele\ugt-32, Cele\K04A8.10, Cele\ugt-65, Cele\ugt-41, Cele\ugt-33, Cele\ugt-47, Cele\ugt-8, Cele\ugt-11, Cele\ugt-10, Cele\ugt-42, Cele\ugt-34, Cele\ugt-38, Cele\H23N18.4, Cele\ugt-1, Cele\ugt-35, Cele\ugt-49, Cele\C03A7.13, Cele\ugt-30, Cele\C55H1.1, Cele\C03A7.12, Cele\ugt-51, Cele\ugt-12, Cele\ugt-16, Cele\ugt-27, Cele\ugt-20, Cele\ugt-45, Cele\ugt-50, Cele\ugt-14, Cele\ugt-56, Cele\ugt-28, Cele\ugt-60, Cele\ugt-9, Cele\ugt-39, Cele\ugt-7, Cele\ugt-58, Cele\ugt-3, Cele\ugt-62, Cele\ugt-29, Cele\F10D2.8, Cele\ugt-37, Cele\ugt-26, Cele\ugt-2, Cele\ugt-23, Cele\ugt-55, Cele\ugt-52, Cele\ugt-19, Cele\ugt-25, Cele\ugt-13, Cele\ugt-61, Cele\ugt-21, Cele\ugt-18, Cele\ugt-22, Cele\ugt-43, Cele\F54C1.1, Cele\ugt-17, Cele\ugt-4, Cele\C23G10.6, Cele\ugt-36, Cele\ugt-44, Cele\ugt-53, Cele\ugt-15, Cele\ugt-40, Cele\ugt-6, Cele\ugt-31" "Xtro\ugt2a1, Xtro\ugt8, Xtro\ugt1a6, Xtro\ugt2b4, Xtro\ugt3a2" "Mmus\Ugt1a1, Mmus\Ugt2b38, Mmus\Ugt2a1, Mmus\Ugt2b35, Mmus\Ugt2b36, Mmus\Ugt3a1, Mmus\Ugt1a2, Mmus\Ugt1a5, Mmus\Ugt2b37, Mmus\Ugt2a3, Mmus\Ugt2b1, Mmus\Ugt3a2, Mmus\Ugt1a7c, Mmus\Ugt8a, Mmus\Ugt1a6b, Mmus\Ugt2b5, Mmus\Ugt1a9, Mmus\Ugt2b34" "Hsap\UGT2B7, Hsap\UGT1A1, Hsap\UGT1A5, Hsap\UGT1A10, Hsap\UGT1A8, Hsap\UGT1A4, Hsap\UGT1A9, Hsap\UGT2B17, Hsap\UGT1A7, Hsap\UGT2B15, Hsap\UGT2B28, Hsap\UGT3A2, Hsap\UGT2A3, Hsap\UGT1A3, Hsap\UGT2B11, Hsap\UGT1A6, Hsap\UGT2B4, Hsap\UGT8, Hsap\UGT3A1, Hsap\UGT2A2, Hsap\UGT2B10" viable FBgn0036920 CG8004 - http://flybase.org/reports/FBgn0036920 protein_coding_gene - protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q13505 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:Q13505 CG8004 "IPR010987:Glutathione S-transferase, C-terminal-like, IPR033468:Metaxin, glutathione S-transferase domain, IPR019564:Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain" CG8004 11-Aug-17 DroID_v2017_08 "Drer\mtx1b, Drer\mtx2, Drer\faxca, Drer\mtx3, Drer\faxcb" - "Cele\cdr-2, Cele\hrg-2, Cele\C25H3.7, Cele\mtx-2, Cele\cdr-4, Cele\Y48C3A.3, Cele\mtx-1, Cele\cdr-6" "Xtro\faxc, Xtro\mtx2" "Mmus\Faxc, Mmus\Mtx1, Mmus\Mtx3, Mmus\Mtx2" "Hsap\FAXC, Hsap\MTX3, Hsap\MTX1, Hsap\MTX2" FBgn0013261 E(var)512 E(var)512 http://flybase.org/reports/FBgn0013261 - gene - - - E(var)512 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0264952 CR44121 - http://flybase.org/reports/FBgn0264952 non_protein_coding_gene - - - "CR44121, lincRNA.S631" - CR44121 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053346 CG33346 - http://flybase.org/reports/FBgn0053346 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - CG33346 "IPR018524:DNA/RNA non-specific endonuclease, active site, IPR001604:DNA/RNA non-specific endonuclease, IPR020821:Extracellular Endonuclease, subunit A" CG33346 11-Aug-17 DroID_v2017_08 "Drer\LOC103910196, Drer\endog, Drer\LOC100333474" Scer\NUC1 Cele\cps-6 - Mmus\Endog "Hsap\ENPP2, Hsap\ENDOG" viable FBgn0025919 mei-160 mei-160 http://flybase.org/reports/FBgn0025919 - gene - reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - mei-160 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030631 CG6227 - http://flybase.org/reports/FBgn0030631 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000000441 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000441 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000000441 nucleus ; GO:0005634 | inferred by curator from GO:0000381 "Prp5, DmRH29, cg6227, CG6227" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG6227 11-Aug-17 DroID_v2017_08 "Drer\ddx42, Drer\ddx46" Scer\PRP5 Cele\F53H1.1 "Xtro\ddx42, Xtro\ddx46" "Mmus\Ddx46, Mmus\Ddx42" "Hsap\DDX46, Hsap\DDX42" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC19975 I 0.369306373 2.208352333 0.614375266 0.762608111 0.764859815 -1.096472677 FBgn0032192 CG5731 - http://flybase.org/reports/FBgn0032192 protein_coding_gene alpha-galactosidase activity ; GO:0004557 | inferred from biological aspect of ancestor with PANTHER:PTN000155295 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000111, InterPro:IPR002241 glycoside catabolic process ; GO:0016139 | inferred from biological aspect of ancestor with PANTHER:PTN000155295" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000155295 CG5731 "IPR000111:Glycoside hydrolase family 27/36, conserved site, IPR002241:Glycoside hydrolase, family 27, IPR013785:Aldolase-type TIM barrel, IPR017853:Glycoside hydrolase superfamily" CG5731 11-Aug-17 DroID_v2017_08 "Drer\gla, Drer\naga" - Cele\gana-1 "Xtro\naga, Xtro\gla" "Mmus\Gla, Mmus\Naga" "Hsap\NAGA, Hsap\GLA" viable FBgn0000378 crt crumpled tips http://flybase.org/reports/FBgn0000378 - gene - - - crt - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,fertile,lethal,recessive,cell lethal,germline clone" wing FBgn0038761 CG17190 - http://flybase.org/reports/FBgn0038761 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17190 - CG17190 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0021951 l(2)k10317 lethal (2) k10317 http://flybase.org/reports/FBgn0021951 - gene - - - l(2)k10317 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024552 l(3)L4060 lethal (3) L4060 http://flybase.org/reports/FBgn0024552 - gene - - - l(3)L4060 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022295 l(1)M76.3 lethal (1) M76.3 http://flybase.org/reports/FBgn0022295 - gene - - - "M76.3, l(1)M76.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038345 CG5213 - http://flybase.org/reports/FBgn0038345 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002343 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype - "cg5213, CG5213" "IPR000504:RNA recognition motif domain, IPR002343:Paraneoplastic encephalomyelitis antigen" CG5213 11-Aug-17 DroID_v2017_08 "Drer\raly, Drer\cirbpa, Drer\eif4h, Drer\hnrnpa3, Drer\ncoa5, Drer\hnrnpa1b, Drer\trnau1apa, Drer\hnrnpc, Drer\rbm34, Drer\hnrnpaba, Drer\wu:fq32h04, Drer\srsf10a, Drer\zgc:55733, Drer\trnau1apb, Drer\eif4ba, Drer\hnrnpabb, Drer\zcrb1, Drer\dazl, Drer\hnrnpd" "Scer\NOP12, Scer\NOP6, Scer\NAB6, Scer\PAB1, Scer\NAM8, Scer\NGR1, Scer\GBP2, Scer\CWC2, Scer\MRN1, Scer\MUD1" - "Xtro\eif4h, Xtro\dazl, Xtro\hnrnpc, Xtro\hnrnpab, Xtro\raly, Xtro\hnrnpa1, Xtro\hnrnpa3, Xtro\cirbp, Xtro\trnau1ap, Xtro\rbm34, Xtro\ralyl, Xtro\hnrnpd, Xtro\eif4b, Xtro\hnrnpdl, Xtro\hnrnpa2b1" "Mmus\Slirp, Mmus\Hnrnpa3, Mmus\Cirbp, Mmus\Tra2b, Mmus\Zcrb1, Mmus\Hnrnpab, Mmus\Rbm31y, Mmus\Raly, Mmus\Gm21379, Mmus\Boll, Mmus\Hnrnpa1, Mmus\Eif4b, Mmus\Srsf10, Mmus\Trnau1ap, Mmus\Eif4h, Mmus\Dazl, Mmus\Hnrnpd, Mmus\Hnrnpa2b1, Mmus\Hnrnpc, Mmus\Srsf12, Mmus\Rbm34" "Hsap\BOLL, Hsap\HNRNPA2B1, Hsap\SRSF10, Hsap\DAZ3, Hsap\DAZ4, Hsap\HNRNPCL1, Hsap\HNRNPA1L2, Hsap\HNRNPA1, Hsap\HNRNPAB, Hsap\RALY, Hsap\HNRNPA3, Hsap\SLIRP, Hsap\RALYL, Hsap\DAZ1, Hsap\EIF4B, Hsap\HNRNPC, Hsap\TRNAU1AP, Hsap\DAZL, Hsap\DAZ2, Hsap\RBM34, Hsap\RBM3, Hsap\EIF4H, Hsap\CIRBP, Hsap\HNRNPD" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0053447 5SrRNA:CR33447 5SrRNA:CR33447 http://flybase.org/reports/FBgn0053447 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33447, 5SrRNA:CR33447" - CR33447 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033767 CG13148 - http://flybase.org/reports/FBgn0033767 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13148 - CG13148 11-Aug-17 DroID_v2017_08 Drer\msantd1 - - - "Mmus\Msantd1, Mmus\Utf1" "Hsap\MSANTD1, Hsap\UTF1" "viable,fertile" DRSC06275 E 0.551626893 1.251402538 1.744400071 -0.75037224 -0.111677946 -0.061736654 FBgn0086285 GS32 - http://flybase.org/reports/FBgn0086285 gene - - - "GS32, 32" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011682 P13 P13 http://flybase.org/reports/FBgn0011682 - gene - - - "Dmcks, P13" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031649 hoe2 hoepel2 http://flybase.org/reports/FBgn0031649 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004680 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004680 "CG15624, hoe2" IPR004680:Citrate transporter-like domain CG15624 11-Aug-17 DroID_v2017_08 Drer\oca2 - Cele\srh-98 Xtro\oca2 Mmus\Oca2 Hsap\OCA2 viable FBgn0044069 E(rst)K45 E(rst)K45 http://flybase.org/reports/FBgn0044069 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "K45, E(rst)K45" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011294 a5 antennal protein 5 http://flybase.org/reports/FBgn0011294 - protein_coding_gene - - - "A5, CG5430, a5" "IPR001858:Phosphatidylethanolamine-binding, conserved site, IPR008914:Phosphatidylethanolamine-binding protein" CG5430 11-Aug-17 DroID_v2017_08 "Drer\mrpl38, Drer\pebp1" "Scer\MRPL35, Scer\TFS1, Scer\YLR179C" "Cele\F40A3.3, Cele\Y69E1A.5" "Xtro\mrpl38, Xtro\pebp4, Xtro\pebp1" "Mmus\Pebp1, Mmus\Mrpl38, Mmus\Pebp4, Mmus\Pbp2" "Hsap\MRPL38, Hsap\PEBP4, Hsap\PEBP1" adult stage " antennal segment 3

, sensillum coeloconica of antennal segment 3

" "partially lethal - majority die,some die during pupal stage" FBgn0038720 CG6231 - http://flybase.org/reports/FBgn0038720 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG6231 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG6231 11-Aug-17 DroID_v2017_08 "Drer\slc22a7b.1, Drer\slc22a7b.3, Drer\oatx, Drer\sv2, Drer\slc22a13, Drer\slc22a7b.2, Drer\LOC101884074, Drer\slc22a21, Drer\zgc:175176, Drer\slc22a6l, Drer\slc22a5, Drer\zmp:0000001102, Drer\LOC100334012" "Scer\TPO1, Scer\HXT2, Scer\QDR1, Scer\AQR1, Scer\QDR2, Scer\GIT1, Scer\HXT9, Scer\PHO84, Scer\HXT5, Scer\FLR1, Scer\YHK8, Scer\DTR1, Scer\TPO3, Scer\TPO2, Scer\QDR3" "Cele\C46C2.2, Cele\C06H5.6, Cele\T22F7.1, Cele\Y51A2D.18, Cele\Y66D12A.13, Cele\oct-1, Cele\ZK892.3, Cele\B0252.3, Cele\C44C10.3, Cele\Y57G11C.23, Cele\C53B4.1, Cele\B0361.11" Xtro\slc22a6 "Mmus\Slc22a28, Mmus\Slc22a29, Mmus\Slc22a22, Mmus\Slc22a2, Mmus\Slc22a23, Mmus\Svop, Mmus\Slc22a20, Mmus\Slc22a4, Mmus\Slc22a14, Mmus\Slc22a21, Mmus\Slc22a26, Mmus\Slc22a5, Mmus\Sv2c, Mmus\Slc22a8, Mmus\Slc22a30, Mmus\Slc22a19, Mmus\Slc22a7, Mmus\Slc22a6, Mmus\Slc22a27, Mmus\Slc22a16" "Hsap\SLC22A4, Hsap\SLC22A7, Hsap\SLC22A25, Hsap\SLC22A9, Hsap\SLC22A24, Hsap\SLC22A2, Hsap\SLC22A1, Hsap\SVOP, Hsap\SLC22A11, Hsap\SV2C, Hsap\SLC22A10, Hsap\SV2B, Hsap\SLC22A5, Hsap\SLC22A8, Hsap\SLC22A6, Hsap\SLC22A23, Hsap\SLC22A12" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266062 Su(var)305 - http://flybase.org/reports/FBgn0266062 gene - - - "Su(var)305, 305" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0038136 CG8774 - http://flybase.org/reports/FBgn0038136 protein_coding_gene peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 angiotensin maturation ; GO:0002003 | inferred from electronic annotation with InterPro:IPR033508 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 CG8774 "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type, IPR033508:Aminopeptidase A" CG8774 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-149p5.1, Drer\erap2, Drer\si:ch211-106j24.1, Drer\enpep, Drer\si:ch211-276a23.5, Drer\lnpep, Drer\anpepa, Drer\npepps, Drer\erap1b, Drer\erap1a, Drer\anpepb, Drer\si:ch211-198g19.1" "Scer\TMA108, Scer\APE2, Scer\AAP1" "Cele\Y67D8C.9, Cele\T07F10.1, Cele\R03G8.4, Cele\Y42A5A.1, Cele\F49B2.6, Cele\AC3.5, Cele\T12E12.6, Cele\R03G8.6, Cele\mnp-1, Cele\VB0395L.1, Cele\Y53F4B.20, Cele\T16G12.1, Cele\pam-1" "Xtro\enpep, Xtro\lnpep, Xtro\lvrn, Xtro\anpep, Xtro\npepps, Xtro\erap1" "Mmus\Enpep, Mmus\Anpep, Mmus\Npepps, Mmus\Lvrn, Mmus\Trhde, Mmus\Lnpep, Mmus\Erap1" "Hsap\NPEPPS, Hsap\LNPEP, Hsap\LVRN, Hsap\ERAP2, Hsap\TRHDE, Hsap\ENPEP, Hsap\ERAP1, Hsap\ANPEP" "viable,fertile" FBgn0262877 CG43232 - http://flybase.org/reports/FBgn0262877 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43232 - CG43232 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023147 Su(mg)3-5 Suppressor of modifier of gypsy 3-5 http://flybase.org/reports/FBgn0023147 - gene - - - Su(mg)3-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031902 Wnt6 Wnt oncogene analog 6 http://flybase.org/reports/FBgn0031902 protein_coding_gene receptor binding ; GO:0005102 | inferred from sequence or structural similarity with wg frizzled binding ; GO:0005109 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 neuron differentiation ; GO:0030182 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 Wnt signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with wg cell fate commitment ; GO:0045165 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with wg "DWnt6, DWnt-6, CG4969, Wnt6, wnt6, D-Wnt-6" "IPR018161:Wnt protein, conserved site, IPR005817:Wnt" CG4969 11-Aug-17 DroID_v2017_08 "Drer\wnt1, Drer\wnt3, Drer\wnt4a, Drer\wnt11, Drer\wnt10b, Drer\wnt8a, Drer\wnt6b, Drer\wnt16, Drer\wnt2bb, Drer\wnt8b, Drer\wnt9b, Drer\wnt2, Drer\wnt4b, Drer\wnt6a, Drer\wnt5a, Drer\wnt5b, Drer\wnt2ba, Drer\wnt11r, Drer\wnt3a, Drer\wnt10a, Drer\wnt9a, Drer\wnt7ba, Drer\LOC568110, Drer\wnt7aa, Drer\wnt7bb" - "Cele\cwn-2, Cele\cwn-1, Cele\egl-20, Cele\mom-2" "Xtro\wnt4, Xtro\wnt8a, Xtro\wnt5b, Xtro\wnt9b.2, Xtro\wnt7c, Xtro\wnt7b, Xtro\wnt16, Xtro\wnt11r, Xtro\wnt9b, Xtro\wnt3a, Xtro\wnt11, Xtro\wnt10b, Xtro\wnt2b, Xtro\wnt8b, Xtro\wnt1, Xtro\wnt7a" "Mmus\Wnt10b, Mmus\Wnt5b, Mmus\Wnt10a, Mmus\Wnt11, Mmus\Wnt2b, Mmus\Wnt1, Mmus\Wnt4, Mmus\Wnt6, Mmus\Wnt9b, Mmus\Wnt16, Mmus\Wnt3, Mmus\Wnt3a, Mmus\Wnt2, Mmus\Wnt5a, Mmus\Wnt9a, Mmus\Wnt8a, Mmus\Wnt7b, Mmus\Wnt7a, Mmus\Wnt8b" "Hsap\WNT10A, Hsap\WNT6, Hsap\WNT5B, Hsap\WNT3A, Hsap\WNT4, Hsap\WNT16, Hsap\WNT2, Hsap\WNT3, Hsap\WNT9B, Hsap\WNT8B, Hsap\WNT9A, Hsap\WNT7B, Hsap\WNT1, Hsap\WNT10B, Hsap\WNT5A, Hsap\WNT11, Hsap\WNT2B, Hsap\WNT7A, Hsap\WNT8A" "viable,size defective,fertile,visible" "wing,posterior,maxillary palpus,wing margin bristle,eye,head" FBgn0028083 l(3)S085009 lethal (3) S085009 http://flybase.org/reports/FBgn0028083 gene - - - "0850/09, l(3)S085009" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0027774 anon-69Db anon-69Db http://flybase.org/reports/FBgn0027774 - non_protein_coding_gene - - - anon-69Db - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031360 CG31937 - http://flybase.org/reports/FBgn0031360 protein_coding_gene - - - "CG17711, CT39259, CG31937" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG31937 11-Aug-17 DroID_v2017_08 "Drer\elovl4a, Drer\elovl7b, Drer\zmp:0000001048, Drer\dhrs7b, Drer\zgc:109982, Drer\elovl4b, Drer\elovl8b, Drer\zgc:101858, Drer\hsd17b1, Drer\rdh8a, Drer\rdh8b, Drer\hsd11b1lb, Drer\elovl8a, Drer\elovl7a, Drer\hsd11b1la, Drer\elovl5, Drer\elovl2, Drer\dhrs7cb, Drer\hsd17b8, Drer\elovl1a, Drer\elovl1b, Drer\dhrs7" Scer\LYS2 "Cele\F26D2.15, Cele\dhs-14, Cele\C06E4.3, Cele\F25D1.5, Cele\Y47G6A.21, Cele\dhs-11, Cele\F28H7.2, Cele\ZK829.1, Cele\dhs-25, Cele\Y47G6A.22" "Xtro\elovl5, Xtro\LOC100124812, Xtro\hsd17b1, Xtro\hsd17b8, Xtro\elovl7, Xtro\rdh8, Xtro\MGC79752, Xtro\dhrs7, Xtro\dhrs7c, Xtro\cbr4, Xtro\elovl1, Xtro\hsd11b1, Xtro\dhrs7b, Xtro\elovl2, Xtro\hsd11b1l, Xtro\hsd11b1l.2" "Mmus\Cbr4, Mmus\Dhrs7, Mmus\Hsd17b1, Mmus\Dhrs7c, Mmus\Elovl5, Mmus\Hsd11b1, Mmus\Rdh8, Mmus\Dhrs7b, Mmus\H2-Ke6, Mmus\Elovl2, Mmus\Elovl4, Mmus\Elovl7" "Hsap\HSD11B1L, Hsap\RDH8, Hsap\ELOVL7, Hsap\HSD17B1, Hsap\DHRS7B, Hsap\ELOVL2, Hsap\ELOVL5, Hsap\HSD11B1, Hsap\ELOVL1, Hsap\DHRS7C, Hsap\CBR4, Hsap\DHRS7, Hsap\ELOVL4, Hsap\HSD17B8" viable FBgn0060881 l(3)S045002b lethal (3) S045002b http://flybase.org/reports/FBgn0060881 gene - - - "0450/02, l(3)S045002b" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0262905 CR43260 - http://flybase.org/reports/FBgn0262905 non_protein_coding_gene - - - "CG43260, CR43260, lincRNA.1020" - CR43260 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065058 snoRNA:684 snoRNA:684 http://flybase.org/reports/FBgn0065058 snoRNA_gene - - - "Dm-684, snoR684, CR33794, snoRNA:684, DmOr_cd6(SnoR684)" - CR33794 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084590 gfr gang of four http://flybase.org/reports/FBgn0084590 gene - - - gfr - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal,recessive,viable" "eye,somatic clone,primary pigment cell,cone cell,wing,wing vein L5,adult head" FBgn0026247 fldB flight defective B at 89B http://flybase.org/reports/FBgn0026247 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "AD170, fldB" - - 11-Aug-17 DroID_v2017_08 - - - - - - "flight defective,recessive,flightless,lethal" FBgn0037617 nom numerous disordered muscles http://flybase.org/reports/FBgn0037617 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 DNA binding ; GO:0003677 | inferred from direct assay" "larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 "CG8145, nom" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG8145 11-Aug-17 DroID_v2017_08 "Drer\LOC101883087, Drer\znf341, Drer\znf770, Drer\znf408, Drer\znfl2a" - "Cele\lin-29, Cele\Y37F4.6, Cele\Y55F3AM.14, Cele\klf-3, Cele\eor-1, Cele\blmp-1, Cele\ztf-23, Cele\M03D4.4" Xtro\znf37a "Mmus\Zfp341, Mmus\Rbak, Mmus\Zfp810, Mmus\Zfp24, Mmus\Zfp369, Mmus\Zfp445, Mmus\Zfp110, Mmus\Zscan5b" "Hsap\ZNF8, Hsap\ZNF341, Hsap\ZNF221, Hsap\ZNF284, Hsap\ZNF560, Hsap\ZNF784" viable FBgn0031733 CG14006 - http://flybase.org/reports/FBgn0031733 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nuclear envelope ; GO:0005635 | inferred from biological aspect of ancestor with PANTHER:PTN001006264 CG14006 IPR019358:NEMP family CG14006 11-Aug-17 DroID_v2017_08 "Drer\nemp2, Drer\nemp1" - Cele\F10C5.2 - "Mmus\Nemp2, Mmus\Nemp1" "Hsap\NEMP2, Hsap\NEMP1" viable FBgn0260629 d01629 - http://flybase.org/reports/FBgn0260629 gene - - - d01629 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0026681 l(1)G0083 lethal (1) G0083 http://flybase.org/reports/FBgn0026681 - gene - - - l(1)G0083 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,male,female,recessive" FBgn0005230 l(3)R15 lethal of Roberts 15 http://flybase.org/reports/FBgn0005230 - gene - - - "l(3)15, l(3)R15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0262691 Su(VGlut)B6 - http://flybase.org/reports/FBgn0262691 gene - - - "B6, Su(VGlut)B6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041088 volcano volcano http://flybase.org/reports/FBgn0041088 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available volcano - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263577 mir-4910 mir-4910 stem loop http://flybase.org/reports/FBgn0263577 miRNA_gene - - - "mir-4910, dme-mir-4910, CR43562" - CR43562 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016901 l(3)72CDc lethal (3) 72CDc http://flybase.org/reports/FBgn0016901 - gene - - - l(3)72CDc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267678 CR46014 - http://flybase.org/reports/FBgn0267678 non_protein_coding_gene - - - CR46014 - CR46014 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020590 anon-57Cg anon-57Cg http://flybase.org/reports/FBgn0020590 - gene - - - anon-57Cg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265720 CR44527 - http://flybase.org/reports/FBgn0265720 non_protein_coding_gene - - - "incRNA.482, CR44527, lincRNA.482" - CR44527 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010044 GstD8 Glutathione S transferase D8 http://flybase.org/reports/FBgn0010044 FBgn0038027 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione peroxidase activity ; GO:0004602 | traceable author statement glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTD8, DmGST27, Gst, GST, GstD27, GST D27, gstD27, CG4421, GstD8, GSTD8, gstd8, gstD8" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG4421 11-Aug-17 DroID_v2017_08 Drer\gstt1b "Scer\URE2, Scer\GTT1" - - - - viable FBgn0004521 l(4)102CDe lethal (4) 102CDe http://flybase.org/reports/FBgn0004521 - gene - - - "l(4)CDe, l(4)PT-1, l(4)6, l(4)102CDe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260234 Xport-B exit protein of rhodopsin and TRP B http://flybase.org/reports/FBgn0260234 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein localization to rhabdomere ; GO:1990146 | inferred from mutant phenotype subrhabdomeral cisterna ; GO:0016029 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "Xport-B, CG42508, XPORT-B, xport-B" - CG42508 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004556 Dbp73D Dead box protein 73D http://flybase.org/reports/FBgn0004556 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 neurogenesis ; GO:0022008 | inferred from mutant phenotype RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "DBP73D, DmRH7, CG9680, Dbp73D" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9680 11-Aug-17 DroID_v2017_08 "Drer\ddx20, Drer\ddx10, Drer\ddx51" "Scer\DBP7, Scer\HCA4, Scer\MSS116, Scer\MRH4, Scer\DBP6" "Cele\ZK512.2, Cele\smut-1, Cele\ZC317.1, Cele\ZK686.2, Cele\Y23H5B.6, Cele\mut-14" "Xtro\ddx51, Xtro\ddx20" "Mmus\Ddx51, Mmus\Ddx20, Mmus\Ddx10" "Hsap\DDX20, Hsap\DDX10, Hsap\DDX51" " adult stage && oogenesis stage , embryonic stage&&larval stage&&adult stage " " egg chamber

, nurse cell

" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0001531 l(1)11Fa lethal (1) 11Fa http://flybase.org/reports/FBgn0001531 - gene - - - l(1)11Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0052054 CG32054 - http://flybase.org/reports/FBgn0052054 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 "CG6645, BcDNA:GM13904, CG32054" "IPR020846:Major facilitator superfamily domain, IPR005828:Major facilitator, sugar transporter-like" CG32054 11-Aug-17 DroID_v2017_08 "Drer\LOC101882338, Drer\slc2a8, Drer\slc2a12, Drer\slc2a13b, Drer\slc2a10, Drer\slc2a6" "Scer\VBA2, Scer\ENB1, Scer\HXT7, Scer\HXT8, Scer\GAL2, Scer\VBA3, Scer\STL1, Scer\YDL199C, Scer\HXT1, Scer\SGE1, Scer\HXT3, Scer\MAL11, Scer\HXT6, Scer\HXT14, Scer\GEX2, Scer\GEX1, Scer\HXT15, Scer\HXT13, Scer\MPH2, Scer\ATR1, Scer\MPH3, Scer\YMR279C, Scer\YFL040W, Scer\AZR1, Scer\HXT9, Scer\HXT11, Scer\VBA5, Scer\HXT16, Scer\RGT2, Scer\HXT2, Scer\SNF3, Scer\ITR1, Scer\HXT10, Scer\YDR387C, Scer\MAL31, Scer\VBA1, Scer\VBA4, Scer\ITR2, Scer\HXT5, Scer\HXT17, Scer\HXT4" - "Xtro\slc2a12, Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a10" "Mmus\Slc2a8, Mmus\Slc2a13, Mmus\Slc2a10, Mmus\Slc2a12, Mmus\Slc2a6" "Hsap\SLC2A10, Hsap\SLC2A12, Hsap\SLC2A6, Hsap\SLC2A8, Hsap\SLC2A13" "viable,visible" mesothoracic tergum FBgn0025794 Su(var)503 Suppressor of variegation 503 http://flybase.org/reports/FBgn0025794 - gene - - - "Su-var(2)503, Su(var)503" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266928 CR45379 - http://flybase.org/reports/FBgn0266928 non_protein_coding_gene - - - CR45379 - CR45379 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038929 CG13408 - http://flybase.org/reports/FBgn0038929 protein_coding_gene - - - CG13408 - CG13408 11-Aug-17 DroID_v2017_08 - - Cele\C50D2.6 - - - viable FBgn0261795 Ote::tkv - http://flybase.org/reports/FBgn0261795 engineered_fusion_gene - - - Ote::tkv - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019935 Rsp80C Responder like http://flybase.org/reports/FBgn0019935 - repeat_region - - - Rsp80C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262216 mir-974 mir-974 stem loop http://flybase.org/reports/FBgn0262216 miRNA_gene - - - "dme-mir-974, 974, mir-974, CR42923, miR-974" - CR42923 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003518 Stigmata Stigmata http://flybase.org/reports/FBgn0003518 - gene - - - "Sta, Stigmata" - - 11-Aug-17 DroID_v2017_08 - - - - - - "scutum,wing" FBgn0035636 Cralbp Cellular retinaldehyde binding protein http://flybase.org/reports/FBgn0035636 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 retinal binding ; GO:0016918 | inferred from sequence or structural similarity transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "CG10546, CRALBP, Cralbp" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG10546 11-Aug-17 DroID_v2017_08 "Drer\ttpal, Drer\clvs2, Drer\sec14l8, Drer\rlbp1a, Drer\ttpa, Drer\rlbp1b, Drer\sec14l7" "Scer\SEC14, Scer\SFH5, Scer\YKL091C" - "Xtro\sec14l1, Xtro\sec14l5, Xtro\ttpa, Xtro\clvs1, Xtro\mospd2, Xtro\clvs2, Xtro\sec14l3, Xtro\rlbp1, Xtro\ttpal" "Mmus\Sec14l2, Mmus\Sec14l3, Mmus\Clvs1, Mmus\Sec14l1, Mmus\Clvs2, Mmus\Rlbp1, Mmus\Ttpal, Mmus\Sec14l5, Mmus\Sec14l4, Mmus\Ttpa" "Hsap\TTPA, Hsap\TTPAL, Hsap\SEC14L5, Hsap\SEC14L4, Hsap\SEC14L2, Hsap\SEC14L3, Hsap\SEC14L6, Hsap\SEC14L1, Hsap\RLBP1, Hsap\CLVS1, Hsap\CLVS2" FBgn0084118 1297 1297 http://flybase.org/reports/FBgn0084118 gene - - - 1297 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011640 lark lark http://flybase.org/reports/FBgn0011640 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 RNA binding ; GO:0003723 | non-traceable author statement mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA binding ; GO:0003723 | inferred from direct assay "eclosion rhythm ; GO:0008062 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype eclosion rhythm ; GO:0008062 | traceable author statement mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype negative regulation of eclosion ; GO:0045804 | inferred from mutant phenotype cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype embryo development ; GO:0009790 | inferred from mutant phenotype eclosion ; GO:0007562 | traceable author statement locomotor rhythm ; GO:0045475 | inferred from mutant phenotype locomotion ; GO:0040011 | NOT traceable author statement locomotor rhythm ; GO:0045475 | traceable author statement circadian rhythm ; GO:0007623 | non-traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 positive regulation of cytoplasmic translation ; GO:2000767 | inferred from mutant phenotype eclosion rhythm ; GO:0008062 | non-traceable author statement actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype inferred from genetic interaction with dco protein localization ; GO:0008104 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "LARK, Lark, CG8597, lark, dLARK" "IPR000504:RNA recognition motif domain, IPR001878:Zinc finger, CCHC-type" CG8597 11-Aug-17 DroID_v2017_08 "Drer\nol8, Drer\rbms1a, Drer\rbm4.3, Drer\elavl4, Drer\elavl1, Drer\adkb, Drer\elavl3, Drer\rbms3, Drer\LOC103909993, Drer\rbm14b, Drer\rbm4.2, Drer\rbms2b, Drer\rbm14a, Drer\rbms2a, Drer\zgc:77262, Drer\rbm4.1, Drer\hug, Drer\elavl2, Drer\adka" - "Cele\exc-7, Cele\R07H5.8, Cele\rnp-1" "Xtro\rbm4b, Xtro\rbm14, Xtro\adk" "Mmus\Rbm14, Mmus\Rbm4, Mmus\Elavl2, Mmus\Rbms2, Mmus\Elavl1, Mmus\Adk, Mmus\Elavl4, Mmus\Rbms1, Mmus\Gm21992, Mmus\Elavl3, Mmus\Rbm4b, Mmus\Rbms3" "Hsap\RBM4B, Hsap\ADK, Hsap\RBM14-RBM4, Hsap\HNRNPCL1, Hsap\RBM14, Hsap\RBMS2, Hsap\RBMS3, Hsap\ELAVL2, Hsap\RBMS1, Hsap\ELAVL3, Hsap\ELAVL1, Hsap\ELAVL4, Hsap\RBM4" "viable,eclosion rhythm defective,lethal - all die before end of pupal stage,some die during pupal stage,locomotor rhythm defective,heat sensitive,visible,flightless,female sterile,male fertile,female fertile,flight defective,lethal,recessive,behavior defective,dominant,eclosion defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die" "wing,scutellar bristle,posterior scutellar bristle,ectopic,embryo,germline clone,adult cuticle" DRSC11362 E 0.402631878 0.029104102 0.66748349 -2.107292227 -0.645745338 -0.153304046 FBgn0011934 tRNA:Asn-GTT-1-8 transfer RNA:Asparagine-GTT 1-8 http://flybase.org/reports/FBgn0011934 "FBgn0003759, FBgn0050319, FBgn0060127" tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "AE002769.trna18-AsnGTT, tRNA:N:GTT:AE002769-g, tRNA:asn5:42Ad, CR30319, chr2R.trna10-AsnGTT, tRNA-Asn-GTT-1-8, tRNA:Asn-GTT-1-8, tRNA:N5:42Ad, AAC" - CR30319 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260006 drd drop dead http://flybase.org/reports/FBgn0260006 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" digestion ; GO:0007586 | inferred from direct assay digestive system process ; GO:0022600 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype defecation ; GO:0030421 | inferred from direct assay - "CG33968, drd, lwf, CG32589, CG5652, BcDNA:GM06434, beltless, blt" "IPR006621:Nose resistant-to-fluoxetine protein, N-terminal, IPR002656:Acyltransferase 3" CG33968 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-5, Cele\oac-20, Cele\rhy-1, Cele\oac-3, Cele\oac-14, Cele\oac-53, Cele\oac-50, Cele\ndg-4, Cele\oac-55, Cele\oac-54, Cele\oac-9, Cele\oac-6, Cele\oac-7, Cele\oac-31, Cele\oac-46, Cele\oac-39, Cele\oac-32, Cele\nrf-6" - Mmus\Oacyl - FBgn0033259 CG11210 - http://flybase.org/reports/FBgn0033259 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003864 "CT31310, CG11210" "IPR003864:Calcium-dependent channel, 7TM region, putative phosphate, IPR032880:Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain, IPR027815:10TM putative phosphate transporter, cytosolic domain" CG11210 11-Aug-17 DroID_v2017_08 "Drer\tmem63bb, Drer\tmem63c, Drer\tmem63a, Drer\tmem63ba" "Scer\SPO75, Scer\RSN1, Scer\CSC1, Scer\PHM7" - "Xtro\tmem63c, Xtro\tmem63a" "Mmus\Tmem63a, Mmus\Tmem63b, Mmus\Tmem63c" "Hsap\TMEM63C, Hsap\TMEM63B, Hsap\TMEM63A" viable FBgn0063418 l(3)3450-E lethal (3) 3450-E http://flybase.org/reports/FBgn0063418 gene - - - l(3)3450-E - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0067397 Su(var)3-9::trx Su(var)3-9::trx http://flybase.org/reports/FBgn0067397 engineered_fusion_gene - - - Su(var)3-9::trx - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022238 lolal lola like http://flybase.org/reports/FBgn0022238 "FBgn0025189, FBgn0034306, FBgn0043381, FBgn0046417" protein_coding_gene "POZ domain binding ; GO:0031208 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q08605 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity" "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from genetic interaction with UniProtKB:Q08605 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 gene silencing ; GO:0016458 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:P26017 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity condensed nuclear chromosome ; GO:0000794 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay PcG protein complex ; GO:0031519 | inferred from physical interaction with UniProtKB:P26017 "CG5738, bat, ban, Ban, l(2)kO2512, EP647, 25/12, l(2)k02512, anon-EST:fe3D3, EP0647, anon-WO0172774.186, lolal, Lolal, LOLAL" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG5738 11-Aug-17 DroID_v2017_08 - - "Cele\bath-25, Cele\bath-23, Cele\bath-9" - - "Hsap\ZBTB43, Hsap\ZBTB9, Hsap\ZBTB37, Hsap\ZBTB12" "lethal,recessive,lethal - all die before end of first instar larval stage,some die during first instar larval stage,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "sex comb,ectopic,presumptive embryonic salivary gland,dorsal trunk primordium,macrochaeta,trichogen cell,tormogen cell,embryonic/larval brain" FBgn0035044 CG3663 - http://flybase.org/reports/FBgn0035044 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000868 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000868 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001797383 CG3663 IPR000868:Isochorismatase-like CG3663 11-Aug-17 DroID_v2017_08 "Drer\isoc1, Drer\isoc2" - Cele\marb-1 "Xtro\isoc2, Xtro\isoc1" "Mmus\Isoc2a, Mmus\Isoc2b, Mmus\Isoc1" "Hsap\ISOC2, Hsap\ISOC1" viable FBgn0265754 CR44561 - http://flybase.org/reports/FBgn0265754 non_protein_coding_gene - - - "CR44561, lincRNA.550" - CR44561 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060904 l(3)S043901b lethal (3) S043901b http://flybase.org/reports/FBgn0060904 gene - - - "0439/01, l(3)S043901b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016626 E(gl)2B Enhancer of glass 2B http://flybase.org/reports/FBgn0016626 - gene - - - E(gl)2B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011081 l(1)Q39 lethal (1) Q39 http://flybase.org/reports/FBgn0011081 FBgn0010210 gene - - - l(1)Q39 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011452 l(3)neo8 lethal (3) neo8 http://flybase.org/reports/FBgn0011452 - gene - - - l(3)neo8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030500 Ndc80 Ndc80 http://flybase.org/reports/FBgn0030500 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000837476 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V3V7 attachment of mitotic spindle microtubules to kinetochore ; GO:0051315 | inferred from biological aspect of ancestor with PANTHER:PTN000068311 chromosome segregation ; GO:0007059 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype kinetochore ; GO:0000776 | inferred from direct assay Ndc80 complex ; GO:0031262 | inferred from direct assay condensed nuclear chromosome kinetochore ; GO:0000778 | inferred from biological aspect of ancestor with PANTHER:PTN000068311 kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay "CG9938, dmNdc80, Ndc80, NDC80, Hec1, hec1, dNdc80" IPR005550:Kinetochore protein Ndc80 CG9938 11-Aug-17 DroID_v2017_08 Drer\ndc80 Scer\NDC80 Cele\ndc-80 Xtro\ndc80 Mmus\Ndc80 Hsap\NDC80 "mitotic cell cycle defective,female sterile,lethal,neuroanatomy defective,viable,visible,female fertile" "condensed nuclear chromosome,metaphase,nucleus,spindle,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0250845 CG1288 - http://flybase.org/reports/FBgn0250845 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:LP10010, BcDNA:AT26093, CG1288, anon-SAGE:Wang-119" - CG1288 11-Aug-17 DroID_v2017_08 - - - - - - DRSC12538 E -0.866037199 -0.632989434 0.042747043 -1.72151673 1.466689238 0.28427631 FBgn0026252 msk moleskin http://flybase.org/reports/FBgn0026252 "FBgn0024487, FBgn0035837" protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 U4 snRNA binding ; GO:0030621 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Ced-12 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y091 U1 snRNA binding ; GO:0030619 | inferred from direct assay U2 snRNA binding ; GO:0030620 | inferred from direct assay epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with rl ommatidial rotation ; GO:0016318 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype inferred from genetic interaction with mbc inferred from genetic interaction with Ced-12 compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype R8 cell differentiation ; GO:0045465 | inferred from mutant phenotype wing cell fate specification ; GO:0035311 | inferred from mutant phenotype MAPK import into nucleus ; GO:0000189 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype snRNP protein import into nucleus ; GO:0006608 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from physical interaction with csw inferred from physical interaction with rl Cajal body organization ; GO:0030576 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype inferred from genetic interaction with sens protein import into nucleus ; GO:0006606 | inferred from direct assay protein import into nucleus ; GO:0006606 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay Cajal body ; GO:0015030 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "dim7, dim-7, DIM-7, CG7935, DmRanBP7, CIP-61, 61, msk, S(ls)2, Msk, Dim-7, Imp7/8, Dim7, Imp7" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR013713:Exportin/Importin, Cse1-like" CG7935 11-Aug-17 DroID_v2017_08 "Drer\ipo7, Drer\ipo8" "Scer\SXM1, Scer\NMD5" - "Xtro\ipo8, Xtro\ipo7" "Mmus\Ipo7, Mmus\Ipo8" "Hsap\IPO7, Hsap\IPO8" "lethal,recessive,visible,somatic clone,cell death defective,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,increased cell death,eye color defective,heat sensitive,lethal - all die during pupal stage,viable" "eye,somatic clone,ommatidium,primary pigment cell,secondary pigment cell,tertiary pigment cell,rhabdomere,cone cell,interommatidial bristle,rhabdomere R7,rhabdomere R8,ommatidial precursor cluster,photoreceptor cell R4,muscle fiber,wing,wing vein L4,wing vein L5,anterior crossvein,posterior crossvein,crossvein,heat sensitive,eye photoreceptor cell,pigment cell,muscle fiber | embryonic stage,chaeta,trichogen cell" FBgn0010167 pur1 purine requiring http://flybase.org/reports/FBgn0010167 - gene - - - "pur-1, pur1" - - 11-Aug-17 DroID_v2017_08 - - - - - - wing vein L4 FBgn0046122 E(To)13 E(To)13 http://flybase.org/reports/FBgn0046122 gene - - - E(To)13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005171 l(2)G572 lethal (2) G572 http://flybase.org/reports/FBgn0005171 - gene - - - l(2)G572 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0027250 l(1)G0254 lethal (1) G0254 http://flybase.org/reports/FBgn0027250 - gene - - - l(1)G0254 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0040554 CR17025 - http://flybase.org/reports/FBgn0040554 non_protein_coding_gene - - - "CG17025, CR17025, pri-mir-252" - CR17025 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037016 CG13252 - http://flybase.org/reports/FBgn0037016 protein_coding_gene - - - CG13252 IPR001007:VWFC domain CG13252 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-266m15.6, Drer\tecta, Drer\si:ch211-252f13.5, Drer\otogl, Drer\crim1, Drer\si:ch211-37e10.2, Drer\scospondin, Drer\nell2a, Drer\ch1073-291c23.1, Drer\fras1, Drer\nell2b, Drer\muc5f, Drer\LOC100147849" - "Cele\crm-1, Cele\F19C6.3" "Xtro\zan, Xtro\LOC100485197, Xtro\LOC100497909, Xtro\fras1, Xtro\crim1, Xtro\tecta.1, Xtro\kcp, Xtro\LOC100492852" "Mmus\Vwce, Mmus\Nell1, Mmus\Zan, Mmus\Nell2, Mmus\Muc2, Mmus\Fras1, Mmus\Fcgbp, Mmus\Muc6, Mmus\9530053A07Rik, Mmus\Kcp, Mmus\Muc5ac, Mmus\Muc5b, Mmus\Otogl, Mmus\Crim1, Mmus\Sspo, Mmus\Tecta" "Hsap\OTOGL, Hsap\VWCE, Hsap\NELL2, Hsap\NELL1, Hsap\FRAS1, Hsap\CRIM1, Hsap\MUC6, Hsap\MUC5B, Hsap\TECTA, Hsap\MUC2" viable FBgn0030032 CG15344 - http://flybase.org/reports/FBgn0030032 protein_coding_gene - - - CG15344 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263612 CR43621 - http://flybase.org/reports/FBgn0263612 non_protein_coding_gene - - - "CR43621, lincRNA.92" - CR43621 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044032 Mod(rst)K46 Mod(rst)K46 http://flybase.org/reports/FBgn0044032 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "K46, Mod(rst)K46" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014863 Mlp84B Muscle LIM protein at 84B http://flybase.org/reports/FBgn0014863 FBgn0011644 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 structural constituent of muscle ; GO:0008307 | inferred from mutant phenotype inferred from genetic interaction with sls muscle tissue development ; GO:0060537 | inferred from expression pattern regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from genetic interaction with sls nucleus ; GO:0005634 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay actin cytoskeleton ; GO:0015629 | colocalizes_with inferred from direct assay "mlp84B, dMlp84B, Mlmu84B, DmLIM-3, DLim-3, CG1019, Mlp84B, MLP84B, mlp, Mlp84b, Mlp, MLP" "IPR001781:Zinc finger, LIM-type" CG1019 11-Aug-17 DroID_v2017_08 "Drer\csrp1a, Drer\csrp1b, Drer\csrp3, Drer\csrp2" Scer\LRG1 Cele\mlp-1 "Xtro\csrp3, Xtro\csrp2, Xtro\csrp1" "Mmus\Csrp3, Mmus\Csrp2, Mmus\Csrp1" "Hsap\CSRP2, Hsap\CSRP3, Hsap\CSRP1" " embryonic stage -- adult stage , embryonic stage , embryonic stage | stage >=14 , embryonic stage | stage 16 " " pharyngeal muscle

, visceral mesoderm

, embryonic/larval somatic muscle

, somatic mesoderm

" embryonic stage " muscle attachment site

, pharyngeal muscle

, embryonic/larval somatic muscle

, larval visceral muscle

" "lethal,recessive,viable,visible" "pupal cuticle,muscle fiber,filamentous actin,trichogen cell,mesothoracic tergum" FBgn0001558 l(1)19Cc lethal (1) 19Cc http://flybase.org/reports/FBgn0001558 - gene - - - "25C4, lElC1, l(1)19Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0060899 l(3)S044215b lethal (3) S044215b http://flybase.org/reports/FBgn0060899 gene - - - "0442/15, l(3)S044215b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0000508 dsx-c88D doublesex cognate 88D http://flybase.org/reports/FBgn0000508 - gene - - - "dsx-c88, dsx-c88D" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028592 l(3)00421 lethal (3) 00421 http://flybase.org/reports/FBgn0028592 gene - - - l(3)00421 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004753 l(3)89Bf lethal (3) 89Bf http://flybase.org/reports/FBgn0004753 - gene - - - l(3)89Bf - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036909 CG15881 - http://flybase.org/reports/FBgn0036909 protein_coding_gene - - mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001591173 "BcDNA:HL01254, CG15881, Ccdc58" IPR019171:Caffeine-induced death protein 2 CG15881 11-Aug-17 DroID_v2017_08 Drer\ccdc58 Scer\MIX23 - Xtro\ccdc58 Mmus\Ccdc58 Hsap\CCDC58 "viable,fertile,immune response defective" FBgn0030807 CG13000 - http://flybase.org/reports/FBgn0030807 protein_coding_gene - - - CG13000 - CG13000 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19519 I -0.128396254 -1.859094899 -0.943614089 0.242461374 0.01070667 0.643580336 FBgn0040850 CG15210 - http://flybase.org/reports/FBgn0040850 protein_coding_gene - - - CG15210 - CG15210 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC27768 K -0.269155104 0.119959772 0.225446542 0.477769682 2.063271969 0.325302084 FBgn0030731 Mfe2 peroxisomal Multifunctional enzyme type 2 http://flybase.org/reports/FBgn0030731 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002198, InterPro:IPR020904 protein homodimerization activity ; GO:0042803 | inferred from direct assay 3R-hydroxyacyl-CoA dehydratase activity ; GO:0080023 | inferred from direct assay enoyl-CoA hydratase activity ; GO:0004300 | inferred from direct assay" "fatty acid beta-oxidation using acyl-CoA oxidase ; GO:0033540 | inferred by curator from GO:0004300,GO:0080023" "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:5213 inferred from sequence model peroxisome ; GO:0005777 | inferred by curator from GO:0004300,GO:0080023" "Mfe2, CG3415, MFE-2, DmMFE-2" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR002539:MaoC-like domain, IPR016040:NAD(P)-binding domain, IPR029069:HotDog domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG3415 11-Aug-17 DroID_v2017_08 Drer\hsd17b4 Scer\FOX2 "Cele\dhrs-4, Cele\nlt-1, Cele\maoc-1, Cele\dhs-28" Xtro\hsd17b4 "Mmus\Scp2d1, Mmus\Hsd17b4" "Hsap\RPP14, Hsap\SCP2D1, Hsap\HSD17B4" viable FBgn0058032 CG40032 - http://flybase.org/reports/FBgn0058032 protein_coding_gene - - - CG40032 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033072 CG17994 - http://flybase.org/reports/FBgn0033072 protein_coding_gene - - - CG17994 - CG17994 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000649 fdg fibrillar dysgenesis http://flybase.org/reports/FBgn0000649 - gene - - - "l(1)fibrillardysgenesis, l(1)fdg, fdg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" "muscle fiber,Z disc | embryonic stage" FBgn0262693 Su(VGlut)B12 - http://flybase.org/reports/FBgn0262693 gene - - - "Su(VGlut)B12, B12" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052264 CG32264 - http://flybase.org/reports/FBgn0052264 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity with MGI:MGI:2659021 actin cytoskeleton reorganization ; GO:0031532 | inferred from sequence or structural similarity with MGI:MGI:2659021 nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:2659021 cytosol ; GO:0005829 | inferred from sequence or structural similarity with MGI:MGI:2659021 "CG14978, CG10860, CG12604, CG10857, CG32264" "IPR004018:RPEL repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG32264 11-Aug-17 DroID_v2017_08 "Drer\phactr3b, Drer\phactr3a, Drer\phactr4a, Drer\phactr4b, Drer\LOC100331268, Drer\phactr2" "Scer\YER158C, Scer\BNI4, Scer\AFR1" Cele\F26H9.2 "Xtro\phactr4, Xtro\phactr1, Xtro\phactr3, Xtro\phactr2" "Mmus\Phactr3, Mmus\Phactr2, Mmus\Phactr4, Mmus\Phactr1" "Hsap\PHACTR3, Hsap\PHACTR4, Hsap\PHACTR1, Hsap\PHACTR2" "viable,fertile" FBgn0016630 E(gl)2F Enhancer of glass 2F http://flybase.org/reports/FBgn0016630 - gene - - - E(gl)2F - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" rhabdomere FBgn0030274 Lint-1 l(3)mbt interacting protein 1 http://flybase.org/reports/FBgn0030274 protein_coding_gene - - polytene chromosome ; GO:0005700 | inferred from mutant phenotype "Lint-1, CG1908, dLint-1" - CG1908 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC28176 IEK 2.902049034 -0.863166332 2.382078794 -1.335135865 -0.727501268 3.584519884 FBgn0020018 Ppox Protoporphyrinogen oxidase http://flybase.org/reports/FBgn0020018 FBgn0046768 protein_coding_gene oxygen-dependent protoporphyrinogen oxidase activity ; GO:0004729 | inferred from sequence or structural similarity with UniProtKB:P50336 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR004572, InterPro:IPR023753 heme biosynthetic process ; GO:0006783 | inferred from sequence or structural similarity with UniProtKB:P50336" mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:P50336 "CG5796, ESTS:9F2T, BcDNA:LD41392, Ppox, PPO" "IPR002937:Amine oxidase, IPR004572:Protoporphyrinogen oxidase, IPR023753:FAD/NAD(P)-binding domain" CG5796 11-Aug-17 DroID_v2017_08 Drer\ppox Scer\HEM14 Cele\glf-1 Xtro\ppox Mmus\Ppox Hsap\PPOX "viable,lethal" DRSC17033 K 0.587372641 0.013652038 0.640129481 0.615431267 -1.612202663 0.462699958 FBgn0065762 l(2)SH0477 lethal (2) SH0477 http://flybase.org/reports/FBgn0065762 gene - - - "l(2)SH0477, l(2)SH2 0477" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004465 Su(P) Suppressor of ref(2)P sterility http://flybase.org/reports/FBgn0004465 - protein_coding_gene "prostaglandin-E synthase activity ; GO:0050220 | inferred from electronic annotation with InterPro:IPR034334 electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR002109, InterPro:IPR011767 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR002109" "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR002109, InterPro:IPR011767" - "CG4086, Su(P)" "IPR002109:Glutaredoxin, IPR010987:Glutathione S-transferase, C-terminal-like, IPR011767:Glutaredoxin active site, IPR012336:Thioredoxin-like fold, IPR034334:Prostaglandin E synthase 2, IPR034335:Prostaglandin E synthase 2, C-terminal" CG4086 11-Aug-17 DroID_v2017_08 Drer\ptgesl - Cele\pges-2 Xtro\ptges2 Mmus\Ptges2 Hsap\PTGES2 "viable,fertile" FBgn0038649 CG7718 - http://flybase.org/reports/FBgn0038649 protein_coding_gene "phosphotransferase activity, for other substituted phosphate groups ; GO:0016780 | inferred from electronic annotation with InterPro:IPR016270" phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR016270 - "CG7718, PL D" "IPR025202:Phospholipase D-like domain, IPR001736:Phospholipase D/Transphosphatidylase, IPR016270:Phospholipase D, phosphatidylserine synthase type" CG7718 11-Aug-17 DroID_v2017_08 Drer\pgs1 Scer\PGS1 Cele\pgs-1 Xtro\pgs1 Mmus\Pgs1 Hsap\PGS1 "partially lethal - majority die,some die during pupal stage" FBgn0030562 CG9400 - http://flybase.org/reports/FBgn0030562 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG9400, anon-WO0140519.10" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain" CG9400 11-Aug-17 DroID_v2017_08 "Drer\glipr2l, Drer\LOC101883528, Drer\LOC100536500, Drer\crispld1b, Drer\r3hdml, Drer\pi15a, Drer\pi15b, Drer\glipr2, Drer\glipr1b, Drer\crispld2, Drer\crispld1a" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\scl-23, Cele\scl-17, Cele\scl-20, Cele\scl-18, Cele\scl-12, Cele\scl-10, Cele\scl-21, Cele\scl-19, Cele\scl-1, Cele\scl-13, Cele\scl-11, Cele\scl-15, Cele\scl-2, Cele\scl-14, Cele\scl-6, Cele\scl-9, Cele\scl-3, Cele\scl-7, Cele\scl-8, Cele\scl-5" "Xtro\MGC108118, Xtro\crisp1, Xtro\glipr2, Xtro\pi15, Xtro\r3hdml, Xtro\crisp2, Xtro\crispld2, Xtro\crisp3" "Mmus\Crisp1, Mmus\Clec18a, Mmus\Pi16, Mmus\Crispld2, Mmus\Glipr1, Mmus\Glipr2, Mmus\Crisp2, Mmus\Crisp4, Mmus\Pi15, Mmus\Crispld1, Mmus\Crisp3, Mmus\R3hdml, Mmus\Glipr1l2, Mmus\Glipr1l1" "Hsap\CRISPLD2, Hsap\GLIPR2, Hsap\CLEC18B, Hsap\R3HDML, Hsap\PI16, Hsap\CLEC18C, Hsap\GLIPR1L1, Hsap\CRISP1, Hsap\GLIPR1L2, Hsap\CLEC18A, Hsap\GLIPR1, Hsap\CRISPLD1, Hsap\CRISP2, Hsap\PI15" viable FBgn0032563 CG15258 - http://flybase.org/reports/FBgn0032563 protein_coding_gene - - - CG15258 - CG15258 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037829 CG14691 - http://flybase.org/reports/FBgn0037829 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 CG14691 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG14691 11-Aug-17 DroID_v2017_08 "Drer\oatx, Drer\slc22a7b.2, Drer\sv2, Drer\sv2c, Drer\sv2ba, Drer\slc22a13, Drer\zgc:175176, Drer\sv2bb, Drer\LOC101884074, Drer\zmp:0000001102, Drer\svopb, Drer\slc22a7b.1, Drer\slc22a21, Drer\slc22a7b.3, Drer\sv2a, Drer\svopl, Drer\LOC100334012, Drer\slc22a6l, Drer\slc22a5, Drer\svopa" "Scer\TPO1, Scer\DTR1, Scer\YHK8, Scer\FLR1, Scer\TPO3, Scer\QDR1, Scer\AQR1, Scer\QDR2, Scer\TPO2, Scer\QDR3, Scer\GAL2" "Cele\oat-1, Cele\svop-1" "Xtro\slc22a6, Xtro\sv2b" "Mmus\Slc22a22, Mmus\Slc22a27, Mmus\Slc22a16, Mmus\Svopl, Mmus\Slc22a6, Mmus\Slc22a2, Mmus\Slc22a23, Mmus\Slc22a14, Mmus\Slc22a8, Mmus\Slc22a29, Mmus\Slc22a19, Mmus\Slc22a26, Mmus\Svop, Mmus\Slc22a20, Mmus\Slc22a7, Mmus\Sv2a, Mmus\Slc22a4, Mmus\Slc22a28, Mmus\Sv2b, Mmus\Sv2c, Mmus\Slc22a30" "Hsap\SLC22A2, Hsap\SLC22A9, Hsap\SLC22A12, Hsap\SVOPL, Hsap\SLC22A8, Hsap\SLC22A6, Hsap\SLC22A1, Hsap\SV2B, Hsap\SLC22A11, Hsap\SLC22A7, Hsap\SLC22A25, Hsap\SLC22A10, Hsap\SV2A, Hsap\SLC22A23, Hsap\SVOP, Hsap\SLC22A24, Hsap\SV2C" viable FBgn0015467 l(2)44Fb lethal (2) 44Fb http://flybase.org/reports/FBgn0015467 - gene - - - l(2)44Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0260336 GSd433 - http://flybase.org/reports/FBgn0260336 gene - - - GSd433 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0002280 l(3)73Ae lethal (3) 73Ae http://flybase.org/reports/FBgn0002280 - gene - - - "l(3)std18, l(3)73Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0023529 CG2918 - http://flybase.org/reports/FBgn0023529 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | traceable author statement extracellular space ; GO:0005615 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG2918, CT9894, EG:25E8.1, GRP170, Grp170" "IPR013126:Heat shock protein 70 family, IPR018181:Heat shock protein 70, conserved site, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG2918 11-Aug-17 DroID_v2017_08 Drer\hyou1 "Scer\SSE1, Scer\LHS1" "Cele\T14G8.3, Cele\T24H7.2" Xtro\hyou1 Mmus\Hyou1 Hsap\HYOU1 lethal FBgn0030929 CG15043 - http://flybase.org/reports/FBgn0030929 protein_coding_gene - - - "BcDNA:RE41194, CG15043" IPR031734:Transcription activator MBF2 CG15043 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0053285 CG33285 - http://flybase.org/reports/FBgn0053285 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs33a04, NEST:bs33a07, CG33285" - CG33285 11-Aug-17 DroID_v2017_08 "Drer\stox2b, Drer\stox1, Drer\stox2a" - Cele\ham-1 - "Mmus\Stox1, Mmus\Stox2" "Hsap\STOX1, Hsap\STOX2" FBgn0265490 BG01442 - http://flybase.org/reports/FBgn0265490 gene - - - BG01442 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039214 puf puffyeye http://flybase.org/reports/FBgn0039214 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:20066 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:20066 positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype inferred from genetic interaction with Myc negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype post-translational protein modification ; GO:0043687 | inferred from mutant phenotype negative regulation of defense response to bacterium ; GO:1900425 | inferred from mutant phenotype regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype regulation of antimicrobial peptide production ; GO:0002784 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "NEST:bs19d10, BcDNA:AT28817, CG5794, Usp34, puf, USP34, Q9VC56" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR016024:Armadillo-type fold, IPR018200:Ubiquitin specific protease, conserved site, IPR011989:Armadillo-like helical, IPR020683:Ankyrin repeat-containing domain, IPR028889:Ubiquitin specific protease domain" CG5794 11-Aug-17 DroID_v2017_08 "Drer\usp34, Drer\usp9, Drer\usp24" "Scer\UBP15, Scer\UBP2" Cele\usp-14 "Xtro\usp34, Xtro\usp9x, Xtro\usp24" "Mmus\Usp34, Mmus\Usp9y, Mmus\Usp9x, Mmus\Usp24" "Hsap\USP9X, Hsap\USP9Y, Hsap\USP24, Hsap\USP34" "some die during larval stage,some die during pupal stage,partially lethal - majority die,short lived,male sterile,size defective,viable,visible,lethal - all die before end of pupal stage,heat sensitive,decreased cell size,lethal - all die during pupal stage,increased cell death" "eye,ommatidium,wing,scutellar bristle,posterior,wing vein" FBgn0038528 CG14326 - http://flybase.org/reports/FBgn0038528 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE19820, CG14326" - CG14326 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031746 CG9029 - http://flybase.org/reports/FBgn0031746 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response ; GO:0006952 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model CG9029 - CG9029 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001869 l(1)XC78 lethal (1) XC78 http://flybase.org/reports/FBgn0001869 - gene - - - l(1)XC78 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052088 sunn sisters unbound http://flybase.org/reports/FBgn0052088 protein_coding_gene - "meiotic sister chromatid cohesion, centromeric ; GO:0051754 | inferred from mutant phenotype" "chromosome, centromeric region ; GO:0000775 | inferred from direct assay" "CG7308, sunn, CG32088, SUNN" - CG32088 11-Aug-17 DroID_v2017_08 Drer\vmp1 - - Xtro\vmp1 Mmus\Vmp1 Hsap\VMP1 "viable,visible" trichogen cell FBgn0045862 btz barentsz http://flybase.org/reports/FBgn0045862 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR028544 translation initiation factor binding ; GO:0031369 | inferred from physical interaction with CG7483 mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR028544 oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from physical interaction with CG7483 oocyte microtubule cytoskeleton polarization ; GO:0008103 | NOT inferred from mutant phenotype pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement bicoid mRNA localization ; GO:0045450 | NOT inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from mutant phenotype exon-exon junction complex ; GO:0035145 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay exon-exon junction complex ; GO:0035145 | inferred from biological aspect of ancestor with PANTHER:PTN000335052 nuclear envelope ; GO:0005635 | inferred from direct assay "Btz, wkl, CG12878, btz" "IPR018545:Btz domain, IPR028544:Protein CASC3" CG12878 11-Aug-17 DroID_v2017_08 Drer\casc3 - "Cele\H28G03.2, Cele\W08E3.2" Xtro\casc3 Mmus\Casc3 Hsap\CASC3 "wild-type,female sterile,cold sensitive,maternal effect,visible,partially lethal - majority die,some die during pupal stage" "pole cell,cold sensitive,ovary,ovariole,maternal effect,abdomen,embryonic abdominal segment,embryonic/first instar larval cuticle,denticle belt,microtubule & oocyte | oogenesis stage S9 | germ-line clone,trichogen cell,mesothoracic tergum" DRSC14566 I -1.690579569 -1.129018823 -0.172981651 1.078007625 0.037486648 -0.24751291 FBgn0065139 l(3)SH113 lethal (3) SH113 http://flybase.org/reports/FBgn0065139 gene - - - "l(3)SH113, l(2)SH3 113" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265137 Spn42Da Serpin 42Da http://flybase.org/reports/FBgn0265137 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from direct assay cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from direct assay negative regulation of endopeptidase activity ; GO:0010951 | inferred from direct assay negative regulation of protein processing ; GO:0010955 | inferred from mutant phenotype negative regulation of peptide hormone processing ; GO:0060570 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "Spn42Da, Spn4, Spn4A, CG9453, sp4, Sp4, spn4, dSerp2, Serp2" "IPR000215:Serpin family, IPR023796:Serpin domain" CG9453 11-Aug-17 DroID_v2017_08 "Drer\serpinh1b, Drer\serpinb1, Drer\serpini1, Drer\serpind1, Drer\serpinh2, Drer\serpinb1l4, Drer\serpinh1a, Drer\serpinb1l2, Drer\serpine1, Drer\zgc:174259, Drer\serpinb1l1, Drer\serpina1l, Drer\serpine3, Drer\serpinc1, Drer\serpina10a, Drer\zgc:173729, Drer\serpine2, Drer\si:ch211-186e20.7, Drer\serpina7, Drer\si:ch1073-416d2.3, Drer\serpinb1l3" - "Cele\srp-7, Cele\srp-3, Cele\srp-1, Cele\srp-6, Cele\srp-2, Cele\srp-8" "Xtro\serpini1, Xtro\serpinb4, Xtro\serpina1, Xtro\serpinb5, Xtro\serpind1, Xtro\serpini2, Xtro\serpine2, Xtro\serpina3k, Xtro\serpina10, Xtro\serpinb1, Xtro\serpinb6, Xtro\serpinb11, Xtro\serpina3m, Xtro\serpinc1, Xtro\serpine1, Xtro\serpina3" "Mmus\Serpina9, Mmus\Serpinb9f, Mmus\Serpinb7, Mmus\Serpinb3b, Mmus\Serpinb1a, Mmus\Serpinb3a, Mmus\Serpini1, Mmus\Serpinb9d, Mmus\Serpinb6a, Mmus\Serpinb8, Mmus\Serpinb9g, Mmus\Serpinb9, Mmus\Serpina1a, Mmus\Serpinb6b, Mmus\Serpina3a, Mmus\Serpinb9c, Mmus\Serpind1, Mmus\Serpina3f, Mmus\Serpinh1, Mmus\Serpina1c, Mmus\Serpina12, Mmus\Serpinb2, Mmus\Serpina11, Mmus\Serpinb1c, Mmus\Serpina7, Mmus\Serpina3k, Mmus\Serpinb6d, Mmus\Serpine3, Mmus\Serpina1d, Mmus\Serpinb3c, Mmus\Serpinb13, Mmus\Serpina3g, Mmus\Serpinb6e, Mmus\Serpinb5, Mmus\Serpina3c, Mmus\Serpina6, Mmus\Serpinb9e, Mmus\Serpina5, Mmus\Serpine2, Mmus\Serpinb10, Mmus\Serpina10, Mmus\Serpina3n, Mmus\Serpinb6c, Mmus\Serpinb12, Mmus\Serpini2, Mmus\Serpinb11, Mmus\Serpinb3d, Mmus\Serpinc1, Mmus\Serpina1f, Mmus\Serpinb9b, Mmus\Serpina16, Mmus\Serping1, Mmus\Serpina3j, Mmus\Gm11397, Mmus\Serpinb1b, Mmus\Serpina1e, Mmus\Serpine1, Mmus\Serpina3i" "Hsap\SERPINB11, Hsap\SERPINA10, Hsap\SERPINA9, Hsap\SERPINA1, Hsap\SERPINI1, Hsap\SERPINB7, Hsap\SERPINB10, Hsap\SERPINB6, Hsap\SERPIND1, Hsap\SERPINB2, Hsap\SERPINA6, Hsap\SERPINH1, Hsap\SERPING1, Hsap\SERPINB12, Hsap\SERPINI2, Hsap\SERPINA7, Hsap\SERPINA5, Hsap\SERPINE1, Hsap\SERPINC1, Hsap\SERPINB13, Hsap\HMSD, Hsap\SERPINB8, Hsap\SERPINE3, Hsap\SERPINB9, Hsap\SERPINA3, Hsap\SERPINB4, Hsap\SERPINB3, Hsap\SERPINB5, Hsap\SERPINE2, Hsap\SERPINA4, Hsap\SERPINA11, Hsap\SERPINB1, Hsap\SERPINA12" FBgn0030509 CG11162 - http://flybase.org/reports/FBgn0030509 protein_coding_gene iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006694 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000221168 lipid biosynthetic process ; GO:0008610 | inferred from electronic annotation with InterPro:IPR006694 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006694 lipid metabolic process ; GO:0006629 | inferred from biological aspect of ancestor with PANTHER:PTN000221168 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000221169 CG11162 IPR006694:Fatty acid hydroxylase CG11162 11-Aug-17 DroID_v2017_08 "Drer\agmo, Drer\msmo1, Drer\sc5d, Drer\faxdc2" "Scer\ERG3, Scer\ERG25" "Cele\drd-1, Cele\F49E12.10" "Xtro\msmo1, Xtro\faxdc2, Xtro\agmo" "Mmus\Msmo1, Mmus\Agmo, Mmus\Sc5d" "Hsap\AGMO, Hsap\FAXDC2, Hsap\SC5D, Hsap\MSMO1" viable FBgn0085605 CG41300 - http://flybase.org/reports/FBgn0085605 protein_coding_gene - - - CG41300 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263486 scaRNA:PsiU6-40 small Cajal body-specific RNA : PsiU6-40 http://flybase.org/reports/FBgn0263486 snoRNA_gene snRNA pseudouridylation guide activity ; GO:0030565 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "scaRNA:PsiU6-40, pugU6-40, snoRNA:skd-a" - CR43601 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065615 l(2)SH0822 lethal (2) SH0822 http://flybase.org/reports/FBgn0065615 gene - - - "l(2)SH0822, l(2)SH2 0822" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020900 Su(osk)C37 Suppressor of oskar C37 http://flybase.org/reports/FBgn0020900 - gene - - - "C37, Su(osk)C37" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028352 l(1)G0166 lethal (1) G0166 http://flybase.org/reports/FBgn0028352 gene - - - l(1)G0166 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014986 l(2)46Db lethal (2) 46Db http://flybase.org/reports/FBgn0014986 - gene - - - "VIII, l(2)46Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0023050 l(1)3Am lethal (1) 3Am http://flybase.org/reports/FBgn0023050 - gene - - - "B2/45.10, l(1)3Am" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014352 ms(3)HB74 ms(3)HB74 http://flybase.org/reports/FBgn0014352 - gene - - - ms(3)HB74 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022973 snRNP200K snRNP200K http://flybase.org/reports/FBgn0022973 - gene - - - "200K/PRP8, snRNP200K" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025479 p35 p35 http://flybase.org/reports/FBgn0025479 - gene - - - "p35, Dmp5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017462 TfIIH-97 Transcription factor IIH-97kD http://flybase.net/reports/FBgn0017462.html FBgn0015830 gene 0006383=transcription from RNA polymerase III promoter 0005675=holo TFIIH complex "TfIIH, TFIIH" 11-Aug-17 DroID_v2017_08 FBgn0065490 l(2)SH1237 lethal (2) SH1237 http://flybase.org/reports/FBgn0065490 gene - - - "l(2)SH1237, l(2)SH2 1237" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010465 l(2)00629 lethal (2) 00629 http://flybase.org/reports/FBgn0010465 - gene - - - l(2)00629 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001547 l(1)16Fa lethal (1) 16Fa http://flybase.org/reports/FBgn0001547 - gene - - - "ME-I, MEI, I[[1]], l(1)16Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,non-rescuable maternal effect,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethalcell lethal,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,polyphasic" "adult epidermis,somatic clone" FBgn0038426 mRpS33 mitochondrial ribosomal protein S33 http://flybase.org/reports/FBgn0038426 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y291 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y291 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y291 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "CG10406, MRP-S33, mRpS33" "IPR013219:Ribosomal protein S27/S33, mitochondrial" CG10406 11-Aug-17 DroID_v2017_08 Drer\mrps33 - Cele\mrps-33 Xtro\mrps33 Mmus\Mrps33 Hsap\MRPS33 "size defective,viable,visible" "adult heart,trichogen cell" FBgn0002207 l(3)67BDe lethal (3) 67BDe http://flybase.org/reports/FBgn0002207 - gene - - - "l(3)e49A4, l(3)e154A1, l(3)67BDe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0024501 Acp31F Accessory gland protein 31F http://flybase.org/reports/FBgn0024501 - gene - - - Acp31F - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male " male accessory gland main cell

, male accessory gland

" FBgn0085582 CR41257 - http://flybase.org/reports/FBgn0085582 non_protein_coding_gene - - - "CG41257, CR41257" - CR41257 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267363 JYalpha JYalpha http://flybase.org/reports/FBgn0267363 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR005775 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250 sodium:potassium-exchanging ATPase activity ; GO:0005391 | inferred from sequence or structural similarity with Atpα potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR005775 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR005775 flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from sequence or structural similarity with Atpα "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR005775 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with Atpα" "CG45760, JYalpha, JYAlpha, CG17923, JY-alpha, CG40625" "IPR023299:P-type ATPase, cytoplasmic domain N, IPR018303:P-type ATPase, phosphorylation site, IPR004014:Cation-transporting P-type ATPase, N-terminal, IPR008250:P-type ATPase, A domain, IPR005775:P-type ATPase, subfamily IIC, IPR001757:P-type ATPase, IPR006068:Cation-transporting P-type ATPase, C-terminal, IPR023214:HAD-like domain, IPR023298:P-type ATPase, transmembrane domain" CG45760 11-Aug-17 DroID_v2017_08 "Drer\atp1a3b, Drer\atp1a1a.1, Drer\atp1a1b, Drer\atp1a1a.4, Drer\atp1a1a.2, Drer\atp1a1a.3, Drer\atp1a3a, Drer\atp1a1a.5, Drer\atp1a2a" "Scer\PMA1, Scer\PMR1" "Cele\catp-1, Cele\catp-2, Cele\catp-3, Cele\catp-4, Cele\eat-6" "Xtro\atp4a, Xtro\atp1a1, Xtro\atp12a, Xtro\atp1a3, Xtro\atp1a2" "Mmus\Atp4a, Mmus\Atp1a4, Mmus\Atp1a2, Mmus\Atp1a1, Mmus\Atp1a3, Mmus\Atp12a" "Hsap\ATP1A2, Hsap\ATP4A, Hsap\ATP1A1, Hsap\ATP12A, Hsap\ATP1A3, Hsap\ATP1A4" FBgn0003192 rab rabbit http://flybase.org/reports/FBgn0003192 - gene - - - rab - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" "microchaeta,adult thorax,scutellum,wing" FBgn0082973 snoRNA:Psi28S-3308 snoRNA:Psi28S-3308 http://flybase.org/reports/FBgn0082973 snoRNA_gene - - - "snoRNA:Psi28S-3308, psi28s-3308, Psi 28S-3308, CR34632, Psi28S-3308, chr3L:816004..816178" - CR34632 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264665 stertorous stertorous http://flybase.org/reports/FBgn0264665 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - stertorous - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval tracheal system,eye,somatic clone" FBgn0263213 CR43383 - http://flybase.org/reports/FBgn0263213 pseudogene_attribute - - - CR43383 - CR43383 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013953 Esp Epidermal stripes and patches http://flybase.org/reports/FBgn0013953 - protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 "CG7005, Esp" "IPR001902:SLC26A/SulP transporter, IPR011547:SLC26A/SulP transporter domain, IPR002645:STAS domain" CG7005 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-117c9.2, Drer\slc26a2, Drer\slc26a4, Drer\slc26a10, Drer\slc26a1, Drer\slc26a5, Drer\slc26a11, Drer\slc26a6l, Drer\slc26a3.2, Drer\slc26a6, Drer\slc26a3.1" "Scer\SUL2, Scer\YPR003C, Scer\YGR125W, Scer\SUL1" "Cele\sulp-3, Cele\sulp-2, Cele\sulp-6, Cele\sulp-1, Cele\sulp-4, Cele\sulp-8, Cele\sulp-7, Cele\sulp-5" "Xtro\slc26a6, Xtro\slc26a7, Xtro\slc26a1, Xtro\slc26a11, Xtro\slc26a4, Xtro\slc26a10, Xtro\slc26a9, Xtro\slc26a5, Xtro\slc26a2" "Mmus\Slc26a9, Mmus\Slc26a3, Mmus\Slc26a4, Mmus\Slc26a2, Mmus\Slc26a8, Mmus\Slc26a7, Mmus\Slc26a10, Mmus\Slc26a5, Mmus\Slc26a1, Mmus\Slc26a6, Mmus\Slc26a11" "Hsap\SLC26A7, Hsap\SLC26A3, Hsap\SLC26A4, Hsap\SLC26A11, Hsap\SLC26A1, Hsap\SLC26A5, Hsap\SLC26A2, Hsap\SLC26A10, Hsap\SLC26A6, Hsap\SLC26A9, Hsap\SLC26A8" "viable,fertile,partially lethal - majority die,some die during pupal stage,mating behavior defective,female limited,female semi-fertile" FBgn0036514 CG12301 - http://flybase.org/reports/FBgn0036514 protein_coding_gene - maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000365650 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern mushroom body development ; GO:0016319 | inferred from mutant phenotype small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000365650 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000365650 CG12301 "IPR006709:Small-subunit processome, Utp14" CG12301 11-Aug-17 DroID_v2017_08 Drer\si:dkey-251i10.3 Scer\UTP14 Cele\F27C1.6 Xtro\utp14a "Mmus\Utp14a, Mmus\Utp14b" "Hsap\UTP14A, Hsap\UTP14C" "neuroanatomy defective,lethal" "adult mushroom body,embryonic/larval neuroblast,ganglion mother cell" FBgn0004911 Eig63F-2 Ecdysone-induced gene 63F 2 http://flybase.org/reports/FBgn0004911 FBgn0052265 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR32265, E63-2, E63F, CG32265, Eip63Fb, Eig63F-2, Eip63F-2" - CR32265 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage -- adult stage , larval stage " embryonic/larval salivary gland

FBgn0010702 l(2)s5211 lethal (2) s5211 http://flybase.org/reports/FBgn0010702 - gene - - - l(2)s5211 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0001177 hat half out http://flybase.org/reports/FBgn0001177 - gene - - - "l(3)84Ca, hat" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266963 CR45414 - http://flybase.org/reports/FBgn0266963 non_protein_coding_gene - - - CR45414 - CR45414 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016040 mpl-2 male prothoracic leg 2 http://flybase.org/reports/FBgn0016040 - gene - - - "MPL-2, mpl-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041837 Eth-AR206 Eth-AR206 http://flybase.org/reports/FBgn0041837 gene - - - "Eth[AR]206, Eth-AR206" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0001697 l(1)ESHS18 lethal (1) ESHS18 http://flybase.org/reports/FBgn0001697 - gene - - - l(1)ESHS18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024732 Drep1 DNA fragmentation factor-related protein 1 http://flybase.org/reports/FBgn0024732 - protein_coding_gene - negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with MGI:MGI:1270845 regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000959605 nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from sequence or structural similarity with HGNC:2772 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003508 "dICAD, Drep1, ICAD/DREP-1, ICAD, DREP-1/dICAD, drep1, DREP-1, CG8357, Rep1, Drep-1" "IPR003508:CIDE-N domain, IPR017299:DNA fragmentation factor subunit alpha" CG8357 11-Aug-17 DroID_v2017_08 "Drer\cideb, Drer\cidea, Drer\cidec, Drer\dffa" - - "Xtro\cidec, Xtro\cidea, Xtro\cideb" "Mmus\Cideb, Mmus\Dffa, Mmus\Cidec, Mmus\Cidea" "Hsap\CIDEB, Hsap\DFFA, Hsap\CIDEC, Hsap\CIDEA" "viable,fertile,cell death defective,conditional" "ovary,chromatin | conditional,nurse cell,conditional,follicle cell,egg chamber" FBgn0000136 as ascute http://flybase.org/reports/FBgn0000136 - gene - - - as - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "scutellum,thorax,wing,eye" FBgn0060579 l(3)S095203b lethal (3) S095203b http://flybase.org/reports/FBgn0060579 gene - - - "0952/03, l(3)S095203b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050320 CG30320 - http://flybase.org/reports/FBgn0050320 protein_coding_gene - - - "BcDNA:RE02263, CG30320" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035483 Mul1 Mitochondrial E3 ubiquitin protein ligase 1 http://flybase.org/reports/FBgn0035483 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:25762 positive regulation of mitochondrial fission ; GO:0090141 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:25762 protein ubiquitination ; GO:0016567 | inferred from mutant phenotype peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:25762 integral component of mitochondrial outer membrane ; GO:0031307 | inferred from sequence or structural similarity with HGNC:25762 "CG1134, MUL1, Mul1" "IPR001841:Zinc finger, RING-type, IPR022170:E3 Ubiquitin ligase, GIDE-type" CG1134 11-Aug-17 DroID_v2017_08 "Drer\LOC402879, Drer\mul1b, Drer\mul1a" "Scer\ASI1, Scer\ASI3" - Xtro\rffl Mmus\Mul1 Hsap\MUL1 "viable,fertile" FBgn0003947 Uf Unfolded http://flybase.org/reports/FBgn0003947 - gene - - - Uf - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" wing FBgn0034335 GstE1 Glutathione S transferase E1 http://flybase.org/reports/FBgn0034335 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay response to oxidative stress ; GO:0006979 | non-traceable author statement response to heat ; GO:0009408 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GST3, CT16545, Gst3, CG5164, DmGSTE1-1, GST-3, DmGST-3, DmGSTE1, Gst-3, Gst55F, Gst-theta 55F, gst-3, GstE1, GSTE1, GST-E1, gstE1, gste1" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG5164 11-Aug-17 DroID_v2017_08 "Drer\gstt1b, Drer\gstt2, Drer\gstr, Drer\eef1e1, Drer\gstt1a, Drer\vars, Drer\eef1g, Drer\mars" "Scer\GTT2, Scer\YGR201C, Scer\TEF4, Scer\GTT1, Scer\CAM1, Scer\URE2" "Cele\gsto-3, Cele\gst-44, Cele\gst-34, Cele\gsto-2, Cele\gst-21, Cele\gst-29" "Xtro\eef1e1, Xtro\eef1g, Xtro\gstt1" "Mmus\Vars, Mmus\Mars, Mmus\Eef1e1, Mmus\Gstt4, Mmus\Gstt3, Mmus\Eef1g, Mmus\Gsto1, Mmus\Gstt2, Mmus\Gstt1" "Hsap\MARS, Hsap\EEF1G, Hsap\GSTT2, Hsap\GSTT1, Hsap\GSTO1, Hsap\GSTT2B, Hsap\EEF1E1, Hsap\VARS" " embryonic stage , embryonic stage -- adult stage , egg stage | unfertilized egg " "

ubiquitous , unfertilized egg | ubiquitous

" "lethal,viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0019800 l(1)05 lethal (1) 05 http://flybase.org/reports/FBgn0019800 - gene - - - l(1)05 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031444 CG9879 - http://flybase.org/reports/FBgn0031444 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000814 "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR000814" - CG9879 IPR000814:TATA-box binding protein CG9879 11-Aug-17 DroID_v2017_08 "Drer\tbpl1, Drer\tbp, Drer\tbpl2" Scer\SPT15 "Cele\tbp-1, Cele\tlf-1" "Xtro\tbp, Xtro\tbpl1, Xtro\tbpl2" "Mmus\Tbp, Mmus\Tbpl1, Mmus\Tbpl2" "Hsap\TBPL2, Hsap\TBP, Hsap\TBPL1" viable FBgn0265558 18.94 - http://flybase.org/reports/FBgn0265558 gene - - - 18.94 - - 11-Aug-17 DroID_v2017_08 - - - - - - learning defective FBgn0039264 CG11786 - http://flybase.org/reports/FBgn0039264 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11786 - CG11786 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039396 CCAP-R Crustacean cardioactive peptide receptor http://flybase.org/reports/FBgn0039396 protein_coding_gene vasopressin receptor activity ; GO:0005000 | inferred from electronic annotation with InterPro:IPR001817 neuropeptide receptor activity ; GO:0008188 | inferred from physical interaction with CCAP neuropeptide receptor activity ; GO:0008188 | inferred from sequence model "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay ecdysis, chitin-based cuticle ; GO:0018990 | traceable author statement" integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG6111, DCCAPR, CG14547, CG33344, anon-WO0170980.47, anon-WO0170980.46, CCAP-R, CCAP receptor, CcapR, CCAPR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001817:Vasopressin receptor, IPR017452:GPCR, rhodopsin-like, 7TM" CG33344 11-Aug-17 DroID_v2017_08 "Drer\ptger1c, Drer\ptger2b, Drer\oxtr, Drer\avpr2ab, Drer\avpr1aa, Drer\ptger2a, Drer\oxtrl, Drer\ptger3, Drer\ptger4a, Drer\si:dkey-178o16.4, Drer\opn3, Drer\ptger1b, Drer\avpr2l, Drer\ptger1a, Drer\gpr39, Drer\ptgfr, Drer\avpr1ab, Drer\ptger4b" - "Cele\srv-19, Cele\T01B11.1, Cele\srv-32, Cele\srv-24, Cele\C04C3.6, Cele\srv-28, Cele\C50H11.13, Cele\C54E10.3, Cele\srv-30, Cele\ZK863.1, Cele\srv-25, Cele\srv-26, Cele\srv-21, Cele\ntr-2, Cele\srv-31, Cele\ntr-1, Cele\srv-27, Cele\ops-1, Cele\srv-17, Cele\srv-29, Cele\srv-22" "Xtro\npsr1, Xtro\oxtr, Xtro\avpr1b" "Mmus\Avpr1b, Mmus\Avpr2, Mmus\Ptger2, Mmus\Avpr1a, Mmus\Ptgfr, Mmus\Ptger4, Mmus\Ptger1, Mmus\Ptger3, Mmus\Ptgdr, Mmus\Tbxa2r, Mmus\Npsr1, Mmus\Oxtr, Mmus\Ptgir" "Hsap\OXTR, Hsap\PTGER3, Hsap\NPSR1, Hsap\PTGIR, Hsap\AVPR1A, Hsap\AVPR2, Hsap\AVPR1B, Hsap\PTGFR, Hsap\TBXA2R, Hsap\PTGER2, Hsap\PTGDR, Hsap\GPR150, Hsap\PTGER1, Hsap\PTGER4" " embryonic stage--larval stage , adult stage " head

viable FBgn0001047 fs(3)HO191 female sterile (3) HO191 http://flybase.org/reports/FBgn0001047 - gene - - - "fs(3)191A, fs(3)HO191" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261817 CG42759 - http://flybase.org/reports/FBgn0261817 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42759 - CG42759 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001172 Had beta Hydroxy acid dehydrogenase http://flybase.org/reports/FBgn0001172 - gene (S)-2-hydroxy-acid oxidase activity ; GO:0003973 | inferred from direct assay - - "HAD, Had" - - 11-Aug-17 DroID_v2017_08 - - - - - - electrophoretic variant FBgn0050104 NT5E-2 Ecto-5'-nucleotidase 2 http://flybase.org/reports/FBgn0050104 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR006146 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR006146 5'-nucleotidase activity ; GO:0008253 | inferred from direct assay "nucleotide catabolic process ; GO:0009166 | inferred from electronic annotation with InterPro:IPR006179, InterPro:IPR008334 dephosphorylation ; GO:0016311 | inferred from direct assay" - "CG30104, CG4837, NT5E-2" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006146:5'-Nucleotidase, conserved site, IPR006179:5'-Nucleotidase/apyrase, IPR008334:5'-Nucleotidase, C-terminal, IPR029052:Metallo-dependent phosphatase-like" CG30104 11-Aug-17 DroID_v2017_08 Drer\nt5e Scer\YHR202W - Xtro\nt5e "Mmus\4933425L06Rik, Mmus\Nt5e" Hsap\NT5E "viable,fertile" FBgn0039487 gb genderblind http://flybase.org/reports/FBgn0039487 protein_coding_gene antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 L-amino acid transmembrane transporter activity ; GO:0015179 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 courtship behavior ; GO:0007619 | non-traceable author statement chemosensory behavior ; GO:0007635 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype glutamine transport ; GO:0006868 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype L-glutamate transport ; GO:0015813 | inferred from mutant phenotype amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 male courtship behavior ; GO:0008049 | inferred from mutant phenotype glutamate secretion ; GO:0014047 | inferred from mutant phenotype taurine transport ; GO:0015734 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 neuromuscular junction ; GO:0031594 | inferred from direct assay "CG6070, anon-WO0118547.295, gb, Gb" IPR002293:Amino acid/polyamine transporter I CG6070 11-Aug-17 DroID_v2017_08 "Drer\slc7a7, Drer\si:dkeyp-120h9.1, Drer\slc7a5, Drer\slc7a8a, Drer\slc7a11, Drer\si:ch73-352p4.8, Drer\zmp:0000001267, Drer\slc7a6, Drer\slc7a10a, Drer\slc7a10b, Drer\slc7a8b, Drer\slc7a9" "Scer\LYP1, Scer\MUP3, Scer\MUP1" "Cele\Y53F4B.12, Cele\aat-4, Cele\aat-8, Cele\aat-2, Cele\aat-7, Cele\aat-3, Cele\aat-6, Cele\aat-9, Cele\aat-5, Cele\aat-1" "Xtro\slc7a7, Xtro\slc7a13, Xtro\slc7a6, Xtro\slc7a5, Xtro\slc7a9, Xtro\slc7a15, Xtro\slc7a11, Xtro\LOC100492274, Xtro\slc7a8, Xtro\slc7a10" "Mmus\Slc7a15, Mmus\Slc7a5, Mmus\Slc7a11, Mmus\Slc7a6, Mmus\Slc7a7, Mmus\Slc7a9, Mmus\Slc7a13, Mmus\Slc7a10, Mmus\Slc7a8, Mmus\Slc7a12" "Hsap\SLC7A10, Hsap\SLC7A8, Hsap\SLC7A9, Hsap\SLC7A11, Hsap\SLC7A6, Hsap\SLC7A13, Hsap\SLC7A5, Hsap\SLC7A7" "neurophysiology defective,courtship behavior defective,male,immune response defective,short lived,conditional,smell perception defective,locomotor behavior defective,viable" "larval neuromuscular junction & postsynaptic membranetub.PU,larval neuromuscular junction & postsynaptic membrane,larval neuromuscular junction & postsynaptic membraneExel6206),embryonic/larval neuromuscular junction,larval neuromuscular junction & bouton" FBgn0083293 E(smoDN)2016 Enhancer of smoDN 2016 http://flybase.org/reports/FBgn0083293 gene - - - E(smoDN)2016 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040673 CG15234 - http://flybase.org/reports/FBgn0040673 protein_coding_gene - - - "BcDNA:LD10051, CG15234" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031216 Zir Zizimin-related http://flybase.org/reports/FBgn0031216 protein_coding_gene "Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from genetic interaction with Cdc42, Rac2" "phagocytosis ; GO:0006909 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype regulation of Rho protein signal transduction ; GO:0035023 | inferred from genetic interaction with Cdc42, Rac2" cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey54, Dm zir, Zir, CG11376, FBgn 31216" "IPR027007:DHR-1 domain, IPR027357:DHR-2 domain, IPR026791:Dedicator of cytokinesis, IPR026798:Dedicator of cytokinesis 6, IPR000008:C2 domain, IPR021816:Dedicator of cytokinesis C/D, N-terminal, IPR010703:Dedicator of cytokinesis, C-terminal" CG11376 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001200, Drer\dock7, Drer\dock8, Drer\dock10, Drer\dock11, Drer\dock9b" - "Cele\F46H5.4, Cele\F22G12.5" "Xtro\dock10, Xtro\dock8, Xtro\dock7, Xtro\dock11, Xtro\dock6" "Mmus\Dock9, Mmus\Dock6, Mmus\Dock7, Mmus\Dock8, Mmus\Dock11, Mmus\Dock10" "Hsap\DOCK8, Hsap\DOCK10, Hsap\DOCK11, Hsap\DOCK9, Hsap\DOCK6, Hsap\DOCK7" "immune response defective,recessive,viable" lamellocyte FBgn0035524 CG11583 - http://flybase.org/reports/FBgn0035524 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000341804 rRNA binding ; GO:0019843 | inferred from sequence or structural similarity with SGD:S000005437 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal large subunit assembly ; GO:0000027 | inferred from sequence or structural similarity with SGD:S000005437 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000341804 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with SGD:S000005437 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000341804 "CG32253, CG11583, dBRX1" "IPR007109:Brix domain, IPR004154:Anticodon-binding, IPR026532:Ribosome biogenesis protein BRX1" CG11583 11-Aug-17 DroID_v2017_08 Drer\bxdc2 Scer\BRX1 "Cele\K12H4.3, Cele\Y54E10A.10" Xtro\brix1 Mmus\Brix1 Hsap\BRIX1 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0062637 EP950 EP950 http://flybase.org/reports/FBgn0062637 gene - - - EP950 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002070 l(2)49Dc lethal (2) 49Dc http://flybase.org/reports/FBgn0002070 - gene - - - "l(2)C, l(2)49Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,non-suppressor of variegation,dominant" FBgn0030665 CG15646 - http://flybase.org/reports/FBgn0030665 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15646 IPR032057:Protein of unknown function DUF4799 CG15646 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037325 CG12147 - http://flybase.org/reports/FBgn0037325 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966" protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with fz peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from biological aspect of ancestor with PANTHER:PTN000225967 protein phosphorylation ; GO:0006468 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 "CG12147, CKIalpha like" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG12147 11-Aug-17 DroID_v2017_08 Drer\csnk1a1 "Scer\HRR25, Scer\YCK3, Scer\YCK1, Scer\YCK2" "Cele\kin-19, Cele\Y39G8C.2, Cele\K09E4.1, Cele\Y111B2A.27" Xtro\csnk1a1 Mmus\Csnk1a1 "Hsap\CSNK1A1L, Hsap\CSNK1A1" viable FBgn0262010 CG42828 - http://flybase.org/reports/FBgn0262010 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG42828, CG6784" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42828 11-Aug-17 DroID_v2017_08 "Drer\ambp, Drer\tfpi2" - Cele\tag-290 - "Mmus\Spint3, Mmus\Ambp, Mmus\Spint4, Mmus\Tfpi" "Hsap\TFPI, Hsap\AMBP, Hsap\SPINT4" "viable,fertile" FBgn0016943 strb starburst http://flybase.org/reports/FBgn0016943 - gene - - - strb - - 11-Aug-17 DroID_v2017_08 - - - - - - wing hair FBgn0267189 CR45629 - http://flybase.org/reports/FBgn0267189 non_protein_coding_gene - - - CR45629 - CR45629 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040033 CG15826 - http://flybase.org/reports/FBgn0040033 protein_coding_gene - - - CG15826 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265901 CR44690 - http://flybase.org/reports/FBgn0265901 non_protein_coding_gene - - - CR44690 - CR44690 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000964 tj traffic jam http://flybase.org/reports/FBgn0000964 "FBgn0020276, FBgn0032786" protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004826, InterPro:IPR008917 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with HGNC:6408 inferred from sequence or structural similarity with MGI:MGI:96909 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype male gonad development ; GO:0008584 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype female gonad development ; GO:0008585 | inferred from mutant phenotype gene expression ; GO:0010467 | inferred from mutant phenotype gonad morphogenesis ; GO:0035262 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "maf-L, CG10034, Dmaf, PL3, maf1, fs(2)eoPL3, fs(2)eo2, fs(2)eo-B, tj, Tj, TJ, DM13" "IPR004826:Basic leucine zipper domain, Maf-type, IPR008917:Transcription factor, Skn-1-like, DNA-binding domain, IPR024874:Transcription factor Maf family" CG10034 11-Aug-17 DroID_v2017_08 "Drer\mafba, Drer\mafga, Drer\mafaa, Drer\mafbb, Drer\mafa, Drer\maff, Drer\mafb, Drer\mafgb, Drer\mafk, Drer\nrl" - Cele\maf-1 "Xtro\nrl, Xtro\mafk, Xtro\maf, Xtro\mafb, Xtro\mafg, Xtro\mafa" "Mmus\Mafg, Mmus\Maf, Mmus\Mafk, Mmus\Nrl, Mmus\Maff, Mmus\Mafb, Mmus\Mafa" "Hsap\MAFB, Hsap\MAF, Hsap\MAFK, Hsap\MAFA, Hsap\NRL, Hsap\MAFF, Hsap\MAFG" "developmental rate defective,female sterile,viable,recessive,sterile,male sterile" "border follicle cell,testis,ovary,testis & fusome,ovarian sheath,ectopic,terminal filament,somatic clone" FBgn0034346 PIG-O Phosphatidylinositol glycan anchor biosynthesis class O http://flybase.org/reports/FBgn0034346 protein_coding_gene mannose-ethanolamine phosphotransferase activity ; GO:0051377 | inferred from biological aspect of ancestor with PANTHER:PTN000552915 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000552915 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000552915 "anon-WO0140519.205, CG12263, PIG-O" "IPR002591:Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG12263 11-Aug-17 DroID_v2017_08 Drer\pigo Scer\GPI13 Cele\C27A12.9 Xtro\pigo Mmus\Pigo Hsap\PIGO "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0000112 ar abdomen rotatum http://flybase.org/reports/FBgn0000112 - gene - multicellular organism development ; GO:0007275 | inferred from mutant phenotype - ar - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,visible,viable,poor,fertile,female semi-sterile" "abdomen,male genitalia,puparium" FBgn0062561 P30 P30 http://flybase.org/reports/FBgn0062561 gene - - - P30 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260720 CR42547 - http://flybase.org/reports/FBgn0260720 non_protein_coding_gene - - - CR42547 - CR42547 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005145 l(2)DTS8 lethal (2) DTS8 http://flybase.org/reports/FBgn0005145 - gene - - - "DTS-L8, l(2)DTS8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,recessive" FBgn0259105 dar7 dendritic arbor reduction 7 http://flybase.org/reports/FBgn0259105 gene - positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype - dar7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058406 CG40406 - http://flybase.org/reports/FBgn0058406 protein_coding_gene - - - CG40406 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262968 CR43279 - http://flybase.org/reports/FBgn0262968 non_protein_coding_gene - - - "CR43279, lincRNA.961" - CR43279 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040992 CG10570 - http://flybase.org/reports/FBgn0040992 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG10570, Dromel_CG10570_FBtr0081122_mORF" - CG10570 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,mesothoracic tergum" FBgn0024909 Taf7 TBP-associated factor 7 http://flybase.org/reports/FBgn0024909 - protein_coding_gene "transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000260034 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement histone acetyltransferase binding ; GO:0035035 | inferred from biological aspect of ancestor with PANTHER:PTN000260034 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from sequence or structural similarity with HGNC:11541 inferred from sequence or structural similarity with SGD:S000004840 transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN000260034 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000260034" "transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11541 inferred from sequence or structural similarity with SGD:S000004840 regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement RNA polymerase II transcriptional preinitiation complex assembly ; GO:0051123 | inferred from biological aspect of ancestor with PANTHER:PTN000260034 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000260034" transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11541 inferred from sequence or structural similarity with SGD:S000004840 transcription factor TFIID complex ; GO:0005669 | inferred from biological aspect of ancestor with PANTHER:PTN000260034 nucleus ; GO:0005634 | non-traceable author statement "TAF[[II]]55, TAF, TFIID, Taf55, dTAF[[II]]55, CG2670, TAF[[II]], TAF7, TAF55, E, anon-84Ec, Taf7" "IPR006751:TAFII55 protein, conserved region" CG2670 11-Aug-17 DroID_v2017_08 Drer\taf7 Scer\TAF7 "Cele\taf-7.1, Cele\taf-7.2" Xtro\taf7 "Mmus\Taf7, Mmus\4933416C03Rik, Mmus\Taf7l" "Hsap\TAF7L, Hsap\TAF7" viable DRSC15445 K -1.420504708 0.186451639 -0.82137932 -0.171355117 1.66579907 2.55220475 FBgn0259727 CG42381 - http://flybase.org/reports/FBgn0259727 protein_coding_gene - - - "CG42381, Dromel_CG9865_FBtr0071680_cx9c_uorf1, CG9865(uORF1)" "IPR027179:Mature-T-Cell Proliferation I type, IPR009069:Cysteine alpha-hairpin motif superfamily" CG42381 11-Aug-17 DroID_v2017_08 Drer\cmc4 Scer\CMC4 - - Mmus\Mtcp1 Hsap\CMC4 FBgn0030357 Sclp Sclp http://flybase.org/reports/FBgn0030357 protein_coding_gene molecular_function ; GO:0003674 | no biological data available muscle system process ; GO:0003012 | inferred from expression pattern inferred from genetic interaction with Mhc cellular_component ; GO:0005575 | no biological data available "CT8171, Sclp, CG2471, dSCLP" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG2471 11-Aug-17 DroID_v2017_08 Drer\lrrc20 - Cele\K08E7.8 Xtro\lrrc20 Mmus\Lrrc20 Hsap\LRRC20 viable FBgn0034411 CG18605 - http://flybase.org/reports/FBgn0034411 protein_coding_gene DNA binding ; GO:0003677 | inferred from sequence or structural similarity with HGNC:21653 ubiquitin protein ligase activity ; GO:0061630 | inferred from sequence or structural similarity with HGNC:21653 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity with HGNC:21653 ubiquitin ligase complex ; GO:0000151 | inferred from sequence or structural similarity with HGNC:21653 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:21653 CG18605 IPR011989:Armadillo-like helical CG18605 11-Aug-17 DroID_v2017_08 "Drer\toporsb, Drer\toporsa, Drer\traip" - "Cele\C32D5.10, Cele\C32D5.11" Xtro\topors "Mmus\Topors, Mmus\Toporsl, Mmus\Traip" "Hsap\TRAIP, Hsap\TOPORS" "visible,partially lethal - majority die,some die during pupal stage" tormogen cell FBgn0060876 l(3)S045602 lethal (3) S045602 http://flybase.org/reports/FBgn0060876 gene - - - "0456/02, l(3)S045602" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266496 s-12 - http://flybase.org/reports/FBgn0266496 gene - - - s-12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262487 CG43077 - http://flybase.org/reports/FBgn0262487 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43077 - CG43077 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020859 cv-3 crossveinless 3 http://flybase.org/reports/FBgn0020859 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available cv-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267699 T:TM-Nrt membrane tethering sequence from Nrt http://flybase.org/reports/FBgn0267699 engineered_tag - - - T:TM-Nrt - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038691 CG5250 - http://flybase.org/reports/FBgn0038691 protein_coding_gene - potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR000402 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR000402 sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred from electronic annotation with InterPro:IPR000402 CG5250 IPR000402:Sodium/potassium-transporting ATPase subunit beta CG5250 11-Aug-17 DroID_v2017_08 "Drer\atp1b3a, Drer\atp1b1a, Drer\atp1b4, Drer\atp1b2b, Drer\atp1b1b, Drer\atp1b2a, Drer\atp1b3b" - "Cele\nkb-1, Cele\nkb-2, Cele\nkb-3" "Xtro\atp4b, Xtro\atp1b1, Xtro\atp1b4, Xtro\atp1b2, Xtro\atp1b3" "Mmus\Atp1b4, Mmus\Atp4b, Mmus\Atp1b3, Mmus\Atp1b1, Mmus\Atp1b2" "Hsap\ATP1B1, Hsap\ATP1B2, Hsap\ATP1B3, Hsap\ATP4B, Hsap\ATP1B4" viable FBgn0010488 NAT1 NAT1 http://flybase.org/reports/FBgn0010488 FBgn0033780 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with SGD:S000003017 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000003017 translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD:S000003017 chaeta development ; GO:0022416 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG3845, NAT1, dNAT1, l(2)01424, Nat1" "IPR003307:W2 domain, IPR003890:MIF4G-like, type 3, IPR003891:Initiation factor eIF-4 gamma, MA3, IPR016024:Armadillo-type fold" CG3845 11-Aug-17 DroID_v2017_08 "Drer\eif4g3b, Drer\eif4g1b, Drer\eif4g2b, Drer\eif4g2a, Drer\eif4g3a, Drer\eif4g1a" "Scer\TIF4632, Scer\TIF4631" Cele\ifg-1 "Xtro\eif4g2, Xtro\eif4g3" "Mmus\Eif4g3, Mmus\Eif4g1, Mmus\Eif4g2" "Hsap\EIF4G1, Hsap\EIF4G3, Hsap\EIF4G2" "viable,fertile,lethal,recessive,partially lethal - majority die,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0028382 cyp33 cyclophilin-33 http://flybase.org/reports/FBgn0028382 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR016304, InterPro:IPR020892, InterPro:IPR024936 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR016304 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR016304, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 phagocytosis ; GO:0006909 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay Prp19 complex ; GO:0000974 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG4886, cyp33, Cyp33, Dcyp33, CYP33" "IPR000504:RNA recognition motif domain, IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR016304:Peptidyl-prolyl cis-trans isomerase E, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR034168:Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, IPR003954:RNA recognition motif domain, eukaryote" CG4886 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-55a19.2, Drer\ppiab, Drer\LOC100333141, Drer\nktr, Drer\ppie, Drer\ppil6, Drer\ppih, Drer\ppib, Drer\ppiaa, Drer\ppid, Drer\ppig" "Scer\CPR1, Scer\CPR3" "Cele\cyn-13, Cele\cyn-3, Cele\cyn-2, Cele\cyn-9, Cele\cyn-5, Cele\cyn-1, Cele\cyn-8, Cele\cyn-11, Cele\cyn-6" "Xtro\ppib, Xtro\ppil6, Xtro\ppih, Xtro\ppid, Xtro\ppie, Xtro\ranbp2, Xtro\ppia, Xtro\nktr, Xtro\ppic" "Mmus\Nktr, Mmus\Ppib, Mmus\Ppie, Mmus\Ppid, Mmus\Ppil6, Mmus\Ppig, Mmus\Ppih, Mmus\Ranbp2, Mmus\Ppic, Mmus\Ppia, Mmus\Ppif" "Hsap\RGPD5, Hsap\NKTR, Hsap\RGPD3, Hsap\RANBP2, Hsap\LOC105371242, Hsap\PPIB, Hsap\RGPD4, Hsap\PPIE, Hsap\PPIAL4C, Hsap\PPIA, Hsap\PPIG, Hsap\PPID, Hsap\RGPD1, Hsap\PPIAL4D, Hsap\PPIF, Hsap\PPIAL4A, Hsap\RGPD6, Hsap\PPIH, Hsap\RGPD2, Hsap\RGPD8, Hsap\PPIC, Hsap\PPIAL4G, Hsap\PPIL6" DRSC05666 E -0.455749141 0.52805237 -1.557667081 0.366418191 -0.546541561 1.278941332 FBgn0014067 Su(tor)3-337 Su(tor)3-337 http://flybase.org/reports/FBgn0014067 - gene - - - Su(tor)3-337 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003572 su(pd) suppressor of purpleoid http://flybase.org/reports/FBgn0003572 - gene - - - su(pd) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065185 l(2)SH2350 lethal (2) SH2350 http://flybase.org/reports/FBgn0065185 gene - - - "l(2)SH2350, l(2)SH2 2350" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060724 l(3)S068111b lethal (3) S068111b http://flybase.org/reports/FBgn0060724 gene - - - "0681/11, l(3)S068111b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0085274 CG34245 - http://flybase.org/reports/FBgn0085274 protein_coding_gene - - - CG34245 - CG34245 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019792 l(1)11A lethal (1) 11A http://flybase.org/reports/FBgn0019792 - gene - - - l(1)11A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263447 CR43470 - http://flybase.org/reports/FBgn0263447 non_protein_coding_gene - - - CR43470 - CR43470 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265923 CR44712 - http://flybase.org/reports/FBgn0265923 non_protein_coding_gene - - - "CR44712, lincRNA.1040" - CR44712 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261716 DJ913 - http://flybase.org/reports/FBgn0261716 gene - - - DJ913 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant FBgn0041136 l(2)44Ff lethal (2) 44Ff http://flybase.org/reports/FBgn0041136 gene - - - l(2)44Ff - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0036226 CG7252 - http://flybase.org/reports/FBgn0036226 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "BcDNA:LP01340, CG7252" IPR002557:Chitin binding domain CG7252 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\cpg-2, Cele\cpg-1, Cele\dct-9, Cele\R02F2.4, Cele\cbd-1, Cele\C39D10.7" - - Hsap\MATN2 viable DRSC21492 K -0.83438418 0.017571379 -0.75938183 0.500859948 1.543918243 -1.150629369 FBgn0013382 acj4 abnormal-chemosensory-jump-4 http://flybase.org/reports/FBgn0013382 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,recessive" FBgn0011220 gor gorp http://flybase.org/reports/FBgn0011220 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - gor - - 11-Aug-17 DroID_v2017_08 - - - - - - male semi-sterile FBgn0265655 CR44462 - http://flybase.org/reports/FBgn0265655 non_protein_coding_gene - - - "lincRNA.310, CR44462" - CR44462 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065500 l(2)SH1210 lethal (2) SH1210 http://flybase.org/reports/FBgn0065500 gene - - - "l(2)SH1210, l(2)SH2 1210" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027956 l(3)S148213 lethal (3) S148213 http://flybase.org/reports/FBgn0027956 gene - - - "1482/13, l(3)S148213" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267439 CR45789 - http://flybase.org/reports/FBgn0267439 non_protein_coding_gene - - - "CR45789, Mgn687" - CR45789 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031721 CG14017 - http://flybase.org/reports/FBgn0031721 protein_coding_gene - - - CG14017 IPR027887:Protein of unknown function DUF4464 CG14017 11-Aug-17 DroID_v2017_08 Drer\si:ch211-57h10.1 - - - Mmus\1700007G11Rik Hsap\C4orf22 FBgn0065527 l(2)SH1117 lethal (2) SH1117 http://flybase.org/reports/FBgn0065527 gene - - - "l(2)SH1117, l(2)SH2 1117" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022942 Cbp80 cap binding protein 80 http://flybase.org/reports/FBgn0022942 FBgn0025614 protein_coding_gene RNA cap binding ; GO:0000339 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 "mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from electronic annotation with InterPro:IPR027159 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 negative regulation of viral genome replication ; GO:0045071 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 RNA interference ; GO:0016246 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004732 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 primary miRNA processing ; GO:0031053 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype primary miRNA processing ; GO:0031053 | inferred from mutant phenotype" mRNA cap binding complex ; GO:0005845 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 precatalytic spliceosome ; GO:0071011 | inferred from direct assay nuclear cap binding complex ; GO:0005846 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CBP80, CG7035, EG:84H4.3, Cbp80, cbp80" "IPR003890:MIF4G-like, type 3, IPR015172:MIF4G-like, type 1, IPR015174:MIF4G-like, type 2, IPR016024:Armadillo-type fold, IPR027159:Nuclear cap-binding protein subunit 1" CG7035 11-Aug-17 DroID_v2017_08 - Scer\STO1 Cele\ncbp-1 Xtro\ncbp1 Mmus\Ncbp1 Hsap\NCBP1 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" DRSC18450 I -1.825106617 0.10782246 -1.352524155 -0.831251279 -1.351898547 -1.352447638 FBgn0263748 CG43673 - http://flybase.org/reports/FBgn0263748 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG43673, CG8473, CG33173" IPR002557:Chitin binding domain CG43673 11-Aug-17 DroID_v2017_08 - - Cele\dct-9 - - - FBgn0035246 CG13928 - http://flybase.org/reports/FBgn0035246 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 negative regulation of translation ; GO:0017148 | inferred from direct assay positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from direct assay - CG13928 "IPR011011:Zinc finger, FYVE/PHD-type, IPR001965:Zinc finger, PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13928 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0033397 Cyp4p3 Cyp4p3 http://flybase.org/reports/FBgn0033397 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CG10843, 4p3, Cyp4p3" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10843 11-Aug-17 DroID_v2017_08 "Drer\cyp26b1, Drer\cyp19a1b, Drer\cyp20a1, Drer\cyp4v8, Drer\cyp19a1a, Drer\cyp46a1.1, Drer\cyp4v7, Drer\cyp46a1.2, Drer\cyp3c2, Drer\cyp26a1, Drer\cyp46a1.4, Drer\cyp3c4, Drer\cyp4f3, Drer\LOC100329425, Drer\cyp26c1, Drer\cyp3c1, Drer\cyp3c3, Drer\cyp4t8, Drer\cyp3a65, Drer\cyp46a1.3" "Scer\DIT2, Scer\ERG5" "Cele\cyp-29A4, Cele\cyp-31A3, Cele\cyp-13A8, Cele\cyp-13A10, Cele\cyp-13A12, Cele\cyp-13A7, Cele\cyp-31A2, Cele\cyp-37B1, Cele\cyp-13A1, Cele\cyp-29A3, Cele\cyp-32B1, Cele\cyp-13A5, Cele\cyp-25A1, Cele\cyp-37A1, Cele\cyp-29A2, Cele\cyp-13A11, Cele\cyp-25A3, Cele\cyp-25A4, Cele\cyp-25A2, Cele\cyp-13A3, Cele\cyp-13A4, Cele\cyp-32A1, Cele\cyp-42A1" "Xtro\LOC100487918, Xtro\cyp20a1, Xtro\cyp4b1.2, Xtro\cyp26c1, Xtro\mgc108213, Xtro\cyp4f2, Xtro\cyp4v2, Xtro\LOC100488227, Xtro\cyp19a1, Xtro\cyp26b1, Xtro\cyp4b1, Xtro\cyp26a1, Xtro\cyp4f22" "Mmus\Cyp4f40, Mmus\Cyp4v3, Mmus\Cyp4a32, Mmus\Cyp3a59, Mmus\Cyp26b1, Mmus\Cyp4f39, Mmus\Cyp3a57, Mmus\Cyp4a14, Mmus\Cyp4a30b, Mmus\Cyp4a12b, Mmus\Cyp4f17, Mmus\Cyp4a12a, Mmus\Cyp3a11, Mmus\Cyp4b1, Mmus\Cyp3a44, Mmus\Cyp4f37, Mmus\Cyp3a41b, Mmus\Cyp3a16, Mmus\Cyp4a31, Mmus\Cyp4f18, Mmus\Cyp3a25, Mmus\Cyp4f16, Mmus\Cyp4a29, Mmus\Cyp4a10, Mmus\Cyp3a13, Mmus\Cyp4x1, Mmus\Cyp20a1, Mmus\Cyp3a41a, Mmus\Cyp46a1, Mmus\Cyp26c1, Mmus\Cyp4f14, Mmus\Cyp19a1, Mmus\Cyp26a1, Mmus\Cyp4f13, Mmus\Cyp4f15" "Hsap\CYP4A22, Hsap\CYP4A11, Hsap\CYP20A1, Hsap\CYP4F11, Hsap\CYP4F8, Hsap\CYP4V2, Hsap\CYP4F12, Hsap\CYP3A4, Hsap\CYP4B1, Hsap\CYP4F2, Hsap\CYP26C1, Hsap\CYP3A43, Hsap\CYP3A7, Hsap\CYP26A1, Hsap\CYP26B1, Hsap\CYP19A1, Hsap\CYP4Z1, Hsap\CYP4X1, Hsap\CYP3A5, Hsap\CYP4F22, Hsap\CYP46A1, Hsap\CYP4F3" "partially lethal - majority die,some die during pupal stage" FBgn0085443 spri sprint http://flybase.org/reports/FBgn0085443 protein_coding_gene "protein kinase binding ; GO:0019901 | inferred from physical interaction with Abl receptor tyrosine kinase binding ; GO:0030971 | inferred from physical interaction with Egfr, Pvr guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from sequence or structural similarity with MGI:MGI:2444024 Ras GTPase binding ; GO:0017016 | inferred from physical interaction with Ras85D Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence model" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000159 regulation of Rab protein signal transduction ; GO:0032483 | inferred from sequence model axon extension ; GO:0048675 | inferred from genetic interaction with DCTN1-p150 inferred from genetic interaction with Strip endocytosis ; GO:0006897 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Egfr inferred from genetic interaction with Cbl inferred from genetic interaction with Pvr cell cortex ; GO:0005938 | inferred from direct assay endocytic vesicle ; GO:0030139 | inferred from direct assay "CG34414, sprint, Rin1, Spri, CG15301, CG12638, CG15297, CG15298, CG15299, CG15300, CG32674, CG33175, anon-WO03040301.275, spri, CG32680" "IPR003123:VPS9 domain, IPR000980:SH2 domain, IPR000159:Ras-associating (RA) domain" CG34414 11-Aug-17 DroID_v2017_08 "Drer\rin3, Drer\rin2, Drer\si:ch211-85n16.4, Drer\rin1a, Drer\si:ch211-168d1.3" "Scer\VPS9, Scer\MUK1" Cele\rin-1 "Xtro\rin3, Xtro\rin2, Xtro\rin1" "Mmus\Rin1, Mmus\Rin2, Mmus\Rin3, Mmus\Rinl" "Hsap\RIN3, Hsap\RIN2, Hsap\RIN1, Hsap\RINL" "viable,fertile" FBgn0020561 anon-VII-I8 anon-VII-I8 http://flybase.org/reports/FBgn0020561 - gene - - - anon-VII-I8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "Bolwig organ,Bolwig nerve" FBgn0031609 CG15443 - http://flybase.org/reports/FBgn0031609 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG15443 "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG15443 11-Aug-17 DroID_v2017_08 Drer\tmco6 - - - Mmus\Tmco6 Hsap\TMCO6 "viable,fertile,visible" "chaeta,trichogen cell" FBgn0035845 CG13675 - http://flybase.org/reports/FBgn0035845 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG13675 IPR002557:Chitin binding domain CG13675 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - FBgn0014117 anon-96Fa anon-96Fa http://flybase.org/reports/FBgn0014117 - gene - - - anon-96Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage , adult stage " " eye-antennal disc

, adult head

" FBgn0014989 l(2)46De lethal (2) 46De http://flybase.org/reports/FBgn0014989 - gene - - - "XI, l(2)46De" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038090 CG10909 - http://flybase.org/reports/FBgn0038090 protein_coding_gene rRNA methyltransferase activity ; GO:0008649 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 histone-glutamine methyltransferase activity ; GO:1990259 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR000692 rRNA methylation ; GO:0031167 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 box C/D snoRNA 3'-end processing ; GO:0000494 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 histone glutamine methylation ; GO:1990258 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 box C/D snoRNP complex ; GO:0031428 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 Cajal body ; GO:0015030 | inferred from biological aspect of ancestor with PANTHER:PTN000036741 CG10909 "IPR000692:Fibrillarin, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG10909 11-Aug-17 DroID_v2017_08 Drer\fbl Scer\NOP1 "Cele\fib-1, Cele\C06E1.9" Xtro\fbl "Mmus\Fbl, Mmus\Fbll1" Hsap\FBL viable FBgn0082370 EP3269 EP3269 http://flybase.org/reports/FBgn0082370 gene - - - EP3269 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0259333 EP-405 - http://flybase.org/reports/FBgn0259333 gene - - - EP-405 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,wing,chaeta" FBgn0002512 l(3)Sp2 lethal (3) Sp2 http://flybase.org/reports/FBgn0002512 - gene - - - l(3)Sp2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011037 l(3)s3123 lethal (3) s3123 http://flybase.org/reports/FBgn0011037 - gene - - - l(3)s3123 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0063364 EP416 BEST:SD01859 http://flybase.org/reports/FBgn0063364 gene - - - "SD01859, EP(3)0416, EP416, BEST:SD01859" - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0038581 CG14314 - http://flybase.org/reports/FBgn0038581 protein_coding_gene - - - CG14314 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG14314 11-Aug-17 DroID_v2017_08 - - "Cele\F59B1.10, Cele\dhs-27, Cele\F59B1.8, Cele\C29F7.1, Cele\C29F7.2, Cele\nhr-246, Cele\H06H21.8" - - - viable FBgn0000745 fs(1)A273 female sterile (1) A273 http://flybase.org/reports/FBgn0000745 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)K1075, fs(1)M114, fs(1)A273" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,female sterile soma-dependent" "dorsal appendage,egg,chorion" FBgn0027266 l(1)G0219 lethal (1) G0219 http://flybase.org/reports/FBgn0027266 - gene - - - l(1)G0219 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" adult abdomen FBgn0039543 CG12428 - http://flybase.org/reports/FBgn0039543 protein_coding_gene carnitine O-octanoyltransferase activity ; GO:0008458 | inferred from sequence or structural similarity with HGNC:2366 fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:2366 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:2366 inferred from sequence model CG12428 IPR000542:Acyltransferase ChoActase/COT/CPT CG12428 11-Aug-17 DroID_v2017_08 Drer\crot Scer\CAT2 "Cele\F41E7.6, Cele\T20B3.1, Cele\W03F9.4" Xtro\crot Mmus\Crot Hsap\CROT FBgn0032967 CG1428 - http://flybase.org/reports/FBgn0032967 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG1428, gi20129693, gi19527787" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG1428 11-Aug-17 DroID_v2017_08 - - "Cele\F10C2.3, Cele\F32D8.2, Cele\T23E1.1, Cele\Y41E3.1, Cele\K03A11.4, Cele\Y38A10A.2, Cele\F32G8.2, Cele\F15H10.7, Cele\M03F8.5, Cele\R03G8.3, Cele\F07C3.3, Cele\Y73F8A.35, Cele\T07G12.3, Cele\R03G8.1" - - - FBgn0024562 l(3)L6241 lethal (3) L6241 http://flybase.org/reports/FBgn0024562 - gene - - - l(3)L6241 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266246 CR44941 - http://flybase.org/reports/FBgn0266246 non_protein_coding_gene - - - "CR44941, lincRNA.757" - CR44941 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060617 l(3)S089303b lethal (3) S089303b http://flybase.org/reports/FBgn0060617 gene - - - "0893/03, l(3)S089303b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027208 l(1)G0384 lethal (1) G0384 http://flybase.org/reports/FBgn0027208 - gene - - - l(1)G0384 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0065409 l(2)SH1571 lethal (2) SH1571 http://flybase.org/reports/FBgn0065409 gene - - - "l(2)SH1571, l(2)SH2 1571" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267176 CR45616 - http://flybase.org/reports/FBgn0267176 non_protein_coding_gene - - - CR45616 - CR45616 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036132 CG18587 - http://flybase.org/reports/FBgn0036132 protein_coding_gene - - - CG18587 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020232 Antp::ro Antp::ro http://flybase.org/reports/FBgn0020232 - engineered_fusion_gene - - - Antp::ro - - 11-Aug-17 DroID_v2017_08 - - - - - - visible ommatidium FBgn0053060 CG33060 - http://flybase.org/reports/FBgn0053060 protein_coding_gene histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000599398 chromatin silencing at telomere ; GO:0006348 | inferred from biological aspect of ancestor with PANTHER:PTN000599398 Set1C/COMPASS complex ; GO:0048188 | inferred from biological aspect of ancestor with PANTHER:PTN000599398 "CG13057, CG33060" IPR007858:Dpy-30 motif CG33060 11-Aug-17 DroID_v2017_08 "Drer\dpy30, Drer\tmem38a" - "Cele\dpy-30, Cele\R05G6.5" "Xtro\dpy30, Xtro\tmem38a, Xtro\tmem38b" "Mmus\Tmem38a, Mmus\Tmem38b, Mmus\Dpy30" "Hsap\TMEM38B, Hsap\TMEM38A, Hsap\DPY30" FBgn0261637 CG42720 - http://flybase.org/reports/FBgn0261637 protein_coding_gene - - - CG42720 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060368 l(3)S138107 lethal (3) S138107 http://flybase.org/reports/FBgn0060368 gene - - - "1381/07, l(3)S138107" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0044516 ifm(2)RU664 indirect flight muscle (2) RU664 http://flybase.org/reports/FBgn0044516 gene - - - "RU664, ifm(2)RU664" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,sterile,recessive,flight defective" "wing,indirect flight muscle" FBgn0038695 CG14280 - http://flybase.org/reports/FBgn0038695 protein_coding_gene - - - CG14280 IPR000859:CUB domain CG14280 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011742 Arp2 Actin-related protein 2 http://flybase.org/reports/FBgn0011742 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR027306 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with HGNC:169 terminal button organization ; GO:0072553 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype regulation of filopodium assembly ; GO:0051489 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from sequence or structural similarity with HGNC:169 cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity cell morphogenesis ; GO:0000902 | inferred from mutant phenotype actin filament ; GO:0005884 | inferred from sequence or structural similarity with SGD:S000002187 Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with HGNC:169 Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity "Arp2, CG9901, ARP2, ARP14D, arp2, Actr14D, Arp14D" "IPR004000:Actin family, IPR027306:Actin-related protein 2, IPR020902:Actin/actin-like conserved site" CG9901 11-Aug-17 DroID_v2017_08 "Drer\zgc:101810, Drer\actr2a, Drer\actr2b" Scer\ARP2 Cele\arx-2 Xtro\actr2 "Mmus\Actr2, Mmus\Actl10" "Hsap\ACTR2, Hsap\ACTL10" " embryonic stage | stage >=9 , embryonic stage | stage 16 " " embryonic central nervous system | presumptive

, embryonic/larval proventriculus

, embryonic/larval hindgut

" "visible,somatic clone,somatic clone - Minute background,neuroanatomy defective,lethal,partially lethal - majority die" "microchaeta,dorsocentral bristle,eye,somatic clone,ommatidium,somatic clone - Minute background,lens,eye photoreceptor cell,eye disc,synapseC57,neuromuscular junctionC57,bouton,trichogen cell,supernumerary,tormogen cell,mesothoracic tergum,actin cytoskeletonHml.PG" DRSC19332 I -1.605137631 -1.471464785 -0.291184 -0.505553853 -0.185682894 -0.153769191 FBgn0016955 tilL touch insensitive larva L http://flybase.org/reports/FBgn0016955 - gene - - - "line 350, tilL" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0266257 CR44952 - http://flybase.org/reports/FBgn0266257 non_protein_coding_gene - - - "CR44952, lincRNA.882" - CR44952 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261735 EC2394 - http://flybase.org/reports/FBgn0261735 gene - - - EC2394 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0052237 CG32237 - http://flybase.org/reports/FBgn0052237 protein_coding_gene - - - "CG13706, CG13703, BcDNA:RE17910, CG32237" "IPR004011:GYR motif, IPR004019:YLP motif" CG32237 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011146 l(1)Q222 lethal (1) Q222 http://flybase.org/reports/FBgn0011146 FBgn0010210 gene - - - l(1)Q222 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0023447 dch dark chestnut http://flybase.org/reports/FBgn0023447 - gene - - - dch - - 11-Aug-17 DroID_v2017_08 - - - - - - visible pigment cell FBgn0015451 l(1)9Fk lethal (1) 9Fk http://flybase.org/reports/FBgn0015451 - gene - - - l(1)9Fk - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022066 l(2)k08002 lethal (2) k08002 http://flybase.net/reports/FBgn0022066.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0083974 CG34138 - http://flybase.org/reports/FBgn0083974 protein_coding_gene - - - CG34138 IPR031720:Protein of unknown function DUF4728 CG34138 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005000 crs cru sterile http://flybase.org/reports/FBgn0005000 - gene - - - crs - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0053730 snmRNA:430:CR33730 snmRNA:430:CR33730 http://flybase.org/reports/FBgn0053730 non_protein_coding_gene - - - "CR33730, snmRNA:430:CR33730" - CR33730 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0012344 Dh44 Diuretic hormone 44 http://flybase.org/reports/FBgn0012344 FBgn0037725 protein_coding_gene "hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR000187 G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with Dh44-R2, Dh44-R1 neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity diuretic hormone activity ; GO:0008613 | non-traceable author statement" hormone-mediated signaling pathway ; GO:0009755 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay locomotor rhythm ; GO:0045475 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from sequence or structural similarity body fluid secretion ; GO:0007589 | inferred from direct assay "extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR000187 extracellular space ; GO:0005615 | inferred by curator from GO:0001664,GO:0009755" "drome-DH44, DH, DH44, Drome-DH[[44]], CG8348, Drm-DH, DH 44, Dh, CRF, DH[[44]], Dh44" "IPR018446:Corticotropin-releasing factor conserved site, IPR000187:Corticotropin-releasing factor" CG8348 11-Aug-17 DroID_v2017_08 - - - - - - "locomotor rhythm defective,viable" FBgn0022269 l(2)k00302 lethal (2) k00302 http://flybase.org/reports/FBgn0022269 - gene - - - l(2)k00302 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065690 l(2)SH0644 lethal (2) SH0644 http://flybase.org/reports/FBgn0065690 gene - - - "l(2)SH0644, l(2)SH2 0644" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027544 CG2217 - http://flybase.org/reports/FBgn0027544 - protein_coding_gene - - - "BcDNA:GH11688, CG2217" IPR031961:Domain of unknown function DUF4780 CG2217 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267975 vib vibrator http://flybase.org/reports/FBgn0267975 protein_coding_gene - transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001666 actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype meiotic cytokinesis ; GO:0033206 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype spermatocyte division ; GO:0048137 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype actomyosin contractile ring maintenance ; GO:0031566 | inferred from mutant phenotype nuclear membrane ; GO:0031965 | inferred from direct assay Nebenkern ; GO:0016006 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay spindle envelope ; GO:0070732 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "gio, vib, CG5269, anon-WO0172774.28, anon-WO0172774.16, anon-WO0172774.12, anon-WO0142479.3, l(3)j7A3, l(3)j4A3, l(3)j7C8, l(3)j5A6, 0450/02, l(3)S045002, l(3)S045002c, 1104/16, l(3)S110416, Vib, PITP-DM, PITP, Dm-PITPalpha" "IPR023393:START-like domain, IPR001666:Phosphatidylinositol transfer protein" CG5269 11-Aug-17 DroID_v2017_08 "Drer\zgc:101640, Drer\pitpnm3, Drer\pitpnbl, Drer\pitpnab, Drer\pitpnaa, Drer\pitpnb, Drer\plrdgb, Drer\pitpnc1" - "Cele\Y71G12B.17, Cele\Y54F10AR.1" "Xtro\pitpnb.2, Xtro\pitpnc1, Xtro\pitpnm3, Xtro\pitpnb" "Mmus\Pitpnm1, Mmus\Pitpna, Mmus\Pitpnm3, Mmus\Pitpnm2, Mmus\Pitpnc1, Mmus\Pitpnb" "Hsap\PITPNA, Hsap\PITPNB, Hsap\PITPNM2, Hsap\PITPNM3, Hsap\PITPNC1, Hsap\PITPNM1" FBgn0004808 fs(2)ltoHL22 female sterile (2) ltoHL22 http://flybase.org/reports/FBgn0004808 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "HL22, fs(2)ltoHL22" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0005344 rstl roughestlike http://flybase.org/reports/FBgn0005344 - gene - - - "lz-l, rstl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced" eye FBgn0001118 gnd grounded http://flybase.org/reports/FBgn0001118 - gene - - - gnd - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" Z disc FBgn0027347 fra::robo1 fra::robo http://flybase.org/reports/FBgn0027347 - engineered_fusion_gene - - - "Robo-DCC, Fra, fra::robo, fra::robo1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,neuroanatomy defective,lethal,partially" "commissure,RP3 motor neuron,transverse nerve,intersegmental nerve,cholinergic neuron,midline crossing tract | embryonic stage 16,longitudinal connective,axonelav.PLu,embryonic/larval somatic muscle,precursor" FBgn0065672 l(2)SH0680 lethal (2) SH0680 http://flybase.org/reports/FBgn0065672 gene - - - "l(2)SH0680, l(2)SH2 0680" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052160 CR32160 - http://flybase.org/reports/FBgn0052160 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RH34065, CG32160, CR32160" - CR32160 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0060524 l(3)S102012b lethal (3) S102012b http://flybase.org/reports/FBgn0060524 gene - - - "1020/12, l(3)S102012b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0083977 CG34141 - http://flybase.org/reports/FBgn0083977 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34141 - CG34141 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025876 opus\gag opus element gag http://flybase.org/reports/FBgn0025876 - transposable_element_gene - - - "ORF1, yoyo\gag, yoyo\Gag, opus\gag, gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266238 CR44933 - http://flybase.org/reports/FBgn0266238 non_protein_coding_gene - - - "CR44933, lincRNA.702" - CR44933 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039890 CG2316 - http://flybase.org/reports/FBgn0039890 protein_coding_gene "ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from electronic annotation with InterPro:IPR011527, InterPro:IPR031238 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011527 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:61 CG2316 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2316 11-Aug-17 DroID_v2017_08 "Drer\LOC101882118, Drer\abcd4, Drer\LOC100537809, Drer\abcd3a, Drer\abcd1, Drer\abcd3b" "Scer\PXA1, Scer\NFT1, Scer\PXA2" "Cele\pmp-2, Cele\pmp-3, Cele\pmp-1, Cele\pmp-4" "Xtro\abcd2, Xtro\abcd1, Xtro\abcd3" "Mmus\Abcd3, Mmus\Abcd2, Mmus\Abcd4, Mmus\Abcd1" "Hsap\ABCD1, Hsap\ABCD2, Hsap\ABCD4, Hsap\ABCD3" "viable,fertile" FBgn0065249 l(2)SH2135 lethal (2) SH2135 http://flybase.org/reports/FBgn0065249 gene - - - "l(2)SH2135, l(2)SH2 2135" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034923 Upf3 Upf3 http://flybase.org/reports/FBgn0034923 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 "gene silencing by miRNA ; GO:0035195 | NOT inferred from mutant phenotype RNA interference ; GO:0016246 | NOT inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype" - "UPF3, CG11184, Upf3, upf3" "IPR005120:Regulator of nonsense-mediated decay, UPF3, IPR000504:RNA recognition motif domain" CG11184 11-Aug-17 DroID_v2017_08 "Drer\upf3b, Drer\upf3a" Scer\UPF3 Cele\smg-4 "Xtro\upf3a, Xtro\upf3b" "Mmus\Upf3a, Mmus\Upf3b" "Hsap\UPF3B, Hsap\UPF3A" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0014020 Rho1 Rho1 http://flybase.org/reports/FBgn0014020 "FBgn0014021, FBgn0024874, FBgn0024880" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from genetic interaction with cv-c GTPase activity ; GO:0003924 | inferred from genetic interaction with RhoGEF64C protein binding ; GO:0005515 | inferred from physical interaction with wash GTPase activity ; GO:0003924 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z7T0 GTPase activity ; GO:0003924 | inferred from direct assay GTPase activity ; GO:0003924 | inferred from genetic interaction with RhoGAPp190 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z7T0 inferred from physical interaction with UniProtKB:P48554 protein binding ; GO:0005515 | inferred from physical interaction with Rok protein binding ; GO:0005515 | inferred from physical interaction with pbl kinase binding ; GO:0019900 | inferred from physical interaction with Rok GTPase activity ; GO:0003924 | non-traceable author statement GTPase activity ; GO:0003924 | inferred from sequence or structural similarity" "small GTPase mediated signal transduction=0007264 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578 axon guidance=0007411; neuroblast proliferation=0007405; mitotic cytokinesis=0000281; lumen formation, open tracheal system=0035149; imaginal disc-derived wing hair organization=0035317 | with fz establishment of planar polarity=0001736; ventral furrow formation=0007370; .. locomotor rhythm=1904059; dorsal closure=0007391; establishment of planar polarity=0001736; protein localization involved in establishment of planar polarity=0090251; imaginal disc-derived leg morphogenesis=0007480; .. filopodium assembly=0051489; ommatidial rotation=0016318; cortical actin cytoskeleton organization=0030866; border follicle cell migration=0007298; .. myoblast fusion=1901739 | with Rok with kirre with Ced-12 maintenance of epithelial cell apical/basal polarity=0045199; .. tube length, open tracheal system=0035159; establishment of imaginal disc-derived wing hair orientation=0001737; dorsal closure, spreading of leading edge cells=0007395; cellular protein localization=0034613; gastrulation involving germ band extension=0010004; .. cell migration=0030334; .. Malpighian tubule size=0035298; .. embryonic cell shape=0016476; adherens junction maintenance=0034334; salivary gland morphogenesis=0007435; pseudocleavage involved in syncytial blastoderm formation=0030589; actin cytoskeleton organization=0030036; epidermal growth factor receptor signaling pathway=0007173 | with cv-c open tracheal system=0007424; actin filament organization=0007015; JNK cascade=0007254; .. axonogenesis=0050770 | with LIMK1 endocytic recycling=0032456; establishment of planar polarity of embryonic epithelium=0042249; dorsal closure, leading edge cell differentiation=0046663; negative .. canonical Wnt signaling pathway=0090090; melanization defense response=0035006; cellularization=0007349; .. left/right symmetry=0007368; imaginal disc-derived wing hair organization=0035317; dorsal closure=0007391; cuticle=0042335 | with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 germ-band extension=0007377; actin cytoskeleton organization=0030036; peripheral nervous system=0007422; establishment of protein localization=0045184; hemocyte migration=0035099; .. cytoskeleton organization=0051493; cytoskeleton organization=0007010; dendrite morphogenesis=0048813; glial cell migration=0008347; myofibril assembly=0030239 | NOT inferred from .. wound healing=0042060; protein localization to adherens junction=0071896; cellular response to DNA damage stimulus=0006974; mitotic actomyosin contractile ring assembly=1903475; branch fusion, open tracheal system=0035147; gastrulation=0007369; cellularization=0007349; spiracle morphogenesis, open tracheal system=0035277; lumen formation, open tracheal system=0035149; dendrite self-avoidance=0070593 | with stan positive .. wound healing=0090303;inferred from .. positive .. protein serine/threonine kinase activity=0071902; ommatidial rotation=0016318; actin cytoskeleton reorganization=0031532;inferred from .. compound eye morphogenesis=0001745 | with p120ctn motor neuron axon guidance=0008045; posterior midgut invagination=0007374; dorsal closure, amnioserosa morphology change=0046664 | NOT inferred from .. establishment or maintenance of actin cytoskeleton polarity=0030950; actin-mediated cell contraction=0070252 | with fog germ cell migration=0008354; neuron projection morphogenesis=0048812; endocytosis=0006897; actin filament bundle assembly=0051017; motor neuron axon guidance=0008045; establishment of tissue polarity=0007164; Wnt signaling pathway=0016055; cell elongation involved in imaginal disc-derived wing morphogenesis=0090254; muscle attachment=0016203 | NOT inferred from .." plasma membrane ; GO:0005886 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay apical plasma membrane ; GO:0016324 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cell hair ; GO:0070451 | inferred from direct assay cell-cell contact zone ; GO:0044291 | inferred from direct assay "Rho1, RhoA, Rho, DmRHO-A, rho1, Rho kinase, rhoA, Rho GTPase, RHO, Dm Rho1, AAF01186, DRho1, DRho, dRhoA, dnRho, rho, Drho1, DrhoA, dRho1, DRhoA, n(2)k07236, E3.10/J3.8, l(2)k02107b, l(2)52Fa, CG8416, Rho A, D-Rho1, RHO1, 8416, RhoN19, 19549712, P48148" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR003578:Small GTPase superfamily, Rho type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8416 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-6b12.5, Drer\rhoca, Drer\rhobtb2a, Drer\rac3b, Drer\cdc42l2, Drer\rhof, Drer\rnd3b, Drer\rnd2, Drer\rhov, Drer\rac3a, Drer\rhobtb1, Drer\cdc42l, Drer\rhogb, Drer\cdc42, Drer\rhoac, Drer\rnd3a, Drer\rhoq, Drer\rhoab, Drer\rhocb, Drer\rhobtb2b, Drer\si:ch211-133l11.10, Drer\zgc:153713, Drer\rhoub, Drer\rhoua, Drer\rhoga, Drer\rhoh, Drer\rac1l, Drer\si:dkey-263f15.2, Drer\rhoaa, Drer\rnd1b, Drer\rhogc, Drer\rac1b, Drer\rac1a, Drer\LOC100331257, Drer\rhoj, Drer\rnd1a" "Scer\RHO1, Scer\RHO5, Scer\RHO3, Scer\CDC42, Scer\RHO2, Scer\RHO4" Cele\rho-1 "Xtro\rhoc, Xtro\rhobtb1, Xtro\rhobtb3, Xtro\rac1, Xtro\rhobtb2, Xtro\rnd1, Xtro\rhob, Xtro\cdc42, Xtro\rhou, Xtro\rhoa.2, Xtro\rhoa, Xtro\rhov, Xtro\rhof, Xtro\rnd3, Xtro\rhoj, Xtro\rac2" "Mmus\Rac1, Mmus\Rhoh, Mmus\Rac2, Mmus\Rhoc, Mmus\Rnd3, Mmus\Rhoq, Mmus\Rhoj, Mmus\Rhof, Mmus\Rhob, Mmus\Rhobtb1, Mmus\Cdc42, Mmus\Rhoa, Mmus\Rhov, Mmus\Rhod, Mmus\Rac3, Mmus\Rhog, Mmus\Rnd2, Mmus\4930544G11Rik, Mmus\Rhou, Mmus\Rnd1, Mmus\Rhobtb3, Mmus\Rhobtb2" "Hsap\RHOF, Hsap\RHOBTB3, Hsap\RHOU, Hsap\RND1, Hsap\RHOQ, Hsap\RND3, Hsap\RHOG, Hsap\RHOBTB2, Hsap\RHOD, Hsap\RHOV, Hsap\RHOBTB1, Hsap\RND2, Hsap\RHOA, Hsap\RHOJ, Hsap\CDC42, Hsap\RHOB, Hsap\RHOC, Hsap\RAC1, Hsap\RAC2, Hsap\RHOH, Hsap\RAC3" " embryonic stage , embryonic stage -- adult stage , adult stage | female , pupal stage , P-stage " "

ubiquitous , organism

" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,visible,some die during embryonic stage,planar polarity defective,somatic clone,cytokinesis defective,mitotic cell cycle defective,wound healing defective,non-suppressor of variegation,non-enhancer of variegation,maternal effect,cell shape defective,increased cell death,cell migration defective,conditional,phototaxis defective,chemical resistant,heat sensitive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" "adherens junction | pupal stageGMR.PF,eye | pupal stage,epithelial cell | pupal stage,hub cell,somatic clone,adherens junction | somatic clone,retina,eye,vacuoleGMR.PF,peripheral glial cell,presumptive embryonic salivary gland,embryonic hemocyte,filzkorper,circular visceral muscle primordium,cortical actin cytoskeleton & spiracular chamber,secondary pigment cell,tertiary pigment cell,photoreceptor cell,rhabdomere,ommatidium,pigment cell,interommatidial bristle,eye photoreceptor cell,morphogenetic furrow,wing hair,extended germ band embryo,embryonic/first instar larval cuticle,anterior,mushroom body & neuron | somatic clone,mushroom body & dendrite | somatic clone,dorsal closure embryo,embryonic epidermis,dorsal,embryonic dorsal epidermis,head,embryonic leading edge cell,embryo,embryonic head,embryonic/larval cuticle,ventral,abdominal ventral denticle belt,adult mushroom body,filopodium,embryonic/larval posterior spiracle,embryonic/larval dorsal trunk,mitotic telophase,mitotic telophase & spindle,actomyosin contractile ring,maternal effect,oocyte,nurse cell ring canal,denticle belt,leg,RP3 motor neuron,embryonic/first instar larval cuticle & embryonic head,embryonic segment,wing,supernumerary,tracheal primordium,presumptive embryonic/larval tracheal system,ommatidial precursor cluster,embryonic/larval trachea,filopodiumen-e16E,mesectoderm,ventral furrow,stomodeal invagination,amnioproctodeal invagination,anterior midgut primordium,mesoderm,embryonic Malpighian tubule tip cell,presumptive embryonic/larval muscle system,ventral longitudinal muscle,dorsal trunk primordium,imaginal disc | third instar larval stage,germline cell,ectopic,germline cell | embryonic stage,external sensory organ precursor cell,embryonic/larval midgut primordium,embryonic hindgut,embryonic/larval hindgut,cortical actin cytoskeleton & embryonic posterior spiracleems.HRE,primordium of embryonic/larval spiracle,posterior spiracle primordium,heat sensitive,border follicle cell,eye photoreceptor cell | third instar larval stage,lamina | third instar larval stage,filopodiumsrp.Hemo,embryonic/larval hemocyte | third instar larval stage,wing disc,disc epithelium proper & dorsal mesothoracic discptc-559.1,wing disc | third instar larval stage,wing blade,eye disc & photoreceptor cell & axonGMR.PF,Bolwig nerve,eye disc & subretinal glial cellGMR.PF,vertical lobe of adult mushroom body,peripheral glial cell | embryonic stage,sensory neuron & axonrepo,lateral trunk primordium,embryonic/larval dorsal anastomosis,mushroom body & dendriteTab2-201Y,mushroom body & dendrite | somatic cloneTab2-201Y,conditional | third instar larval stage,embryonic/larval hemolymph | third instar larval stage,midline crossing tract | embryonic stage 16,ventral nerve cord commissure | embryonic stage 16,anterior embryonic/larval midgut,vacuoleAppl.G1a,blastoderm embryo,germline clone,actin cytoskeleton | blastoderm stage | germline clone,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,actin filament & embryonic/larval tracheal systembtl.PS,adult cuticle,adult abdomen" DRSC07530 IE -1.087312644 -1.935045606 -0.616335897 -1.676516344 -0.002646985 -0.002958944 FBgn0034756 Cyp6d2 Cyp6d2 http://flybase.org/reports/FBgn0034756 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 response to camptothecin ; GO:1901563 | inferred from mutant phenotype" - "6d2, CG4373, Cyp6d2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG4373 11-Aug-17 DroID_v2017_08 "Drer\cyp3c2, Drer\cyp3c4, Drer\cyp3a65, Drer\cyp3c1, Drer\tbxas1, Drer\cyp3c3" Scer\ERG11 "Cele\cyp-13A10, Cele\cyp-13B2, Cele\cyp-23A1, Cele\cyp-13A2, Cele\cyp-43A1, Cele\cyp-44A1, Cele\cyp-13B1, Cele\cyp-25A2, Cele\cyp-25A6, Cele\cyp-13A4, Cele\cyp-13A3, Cele\cyp-13A1, Cele\cyp-13A5, Cele\cyp-25A3, Cele\cyp-13A12, Cele\cyp-13A8, Cele\cyp-13A11, Cele\cyp-13A6, Cele\cyp-13A7, Cele\cyp-25A1, Cele\cyp-25A4" "Xtro\cyp3a4, Xtro\LOC100494419, Xtro\tbxas1, Xtro\cyp3a5" "Mmus\Cyp3a13, Mmus\Cyp3a41b, Mmus\Cyp3a59, Mmus\Cyp3a57, Mmus\Cyp3a25, Mmus\Cyp3a11, Mmus\Tbxas1, Mmus\Cyp3a44, Mmus\Cyp3a41a, Mmus\Cyp3a16" "Hsap\CYP3A7, Hsap\CYP3A4, Hsap\CYP3A7-CYP3A51P, Hsap\TBXAS1, Hsap\CYP3A5, Hsap\CYP3A43" "chemical sensitive,viable" FBgn0031220 CG4822 - http://flybase.org/reports/FBgn0031220 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" sleep ; GO:0030431 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 CG4822 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG4822 11-Aug-17 DroID_v2017_08 "Drer\abcg4a, Drer\abcg2a, Drer\abcg1, Drer\abcg4b, Drer\abcg8, Drer\abch1, Drer\abcg5, Drer\abcg2b" "Scer\ADP1, Scer\ARB1, Scer\PDR12, Scer\PDR18, Scer\PDR10, Scer\YOL075C" "Cele\wht-4, Cele\abch-1, Cele\wht-1" "Xtro\abcg8, Xtro\abcg5" "Mmus\Abcg8, Mmus\Abcg3, Mmus\Abcg2, Mmus\Abcg5, Mmus\Abcg4, Mmus\Abcg1" "Hsap\ABCG4, Hsap\ABCG5, Hsap\ABCG8, Hsap\ABCG1" "viable,lethal" FBgn0001666 l(1)EN1 lethal (1) from Eugene Nonautonomous 1 http://flybase.org/reports/FBgn0001666 - gene - - - l(1)EN1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval salivary gland,gastric caecum,fat body" FBgn0036742 CG7497 - http://flybase.org/reports/FBgn0036742 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR008365 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity actin filament organization ; GO:0007015 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR008365, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "CHED-related, BcDNA:GH27361, anon-WO0170980.89, anon-WO0170980.88, CG7497" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR008365:Prostanoid receptor, IPR017452:GPCR, rhodopsin-like, 7TM" CG7497 11-Aug-17 DroID_v2017_08 "Drer\ptgir, Drer\ptgfr, Drer\ptger4b, Drer\ptger2b, Drer\ptger1a, Drer\ptger4a, Drer\ptger1b, Drer\ptger3, Drer\ptger1c, Drer\ptger2a" - - "Xtro\ptger1, Xtro\tbxa2r, Xtro\ptgir, Xtro\ptger4, Xtro\ptger3, Xtro\ptger2" "Mmus\Ptger1, Mmus\Ptgdr, Mmus\Ptger2, Mmus\Ptger3, Mmus\Ptgfr, Mmus\Ptgir, Mmus\Tbxa2r, Mmus\Ptger4" "Hsap\PTGER4, Hsap\ADRA1B, Hsap\PTGIR, Hsap\PTGER2, Hsap\PTGER1, Hsap\PTGDR, Hsap\TBXA2R, Hsap\PTGER3, Hsap\PTGFR" "partially lethal - majority die,visible" trichogen cell FBgn0031322 CG5001 - http://flybase.org/reports/FBgn0031322 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR008971 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971 - CG5001 "IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site" CG5001 11-Aug-17 DroID_v2017_08 "Drer\dnajb1b, Drer\dnajb12a, Drer\dnajc18, Drer\zgc:122979, Drer\dnajb13, Drer\dnajb2, Drer\dnajb1a, Drer\dnajb4, Drer\dnajc22, Drer\dnajb5, Drer\dnajb12b, Drer\dnajb14, Drer\dnajb9a" "Scer\SCJ1, Scer\JJJ1, Scer\ERJ5, Scer\HLJ1, Scer\APJ1, Scer\SIS1" "Cele\dnj-13, Cele\dnj-22, Cele\F54F2.9, Cele\dnj-19, Cele\dnj-1, Cele\dnj-12" "Xtro\dnajc18, Xtro\dnajc22, Xtro\dnajb13, Xtro\dnajb1, Xtro\dnajb12, Xtro\dnajb6, Xtro\dnajb4, Xtro\dnajb2, Xtro\dnajb9, Xtro\dnajb14, Xtro\dnajb5" "Mmus\Dnajb2, Mmus\Dnajb4, Mmus\Dnajb12, Mmus\Dnajb7, Mmus\Dnajc18, Mmus\Dnajc21, Mmus\Dnajb5, Mmus\Dnajb6, Mmus\Dnajb3, Mmus\Dnajb8, Mmus\Dnajb9, Mmus\Dnajb14, Mmus\Dnajb1, Mmus\Dnajc22, Mmus\Dnajb13" "Hsap\DNAJB4, Hsap\DNAJC22, Hsap\DNAJB6, Hsap\DNAJB5, Hsap\DNAJB13, Hsap\DNAJB2, Hsap\DNAJB8, Hsap\DNAJB14, Hsap\DNAJB7, Hsap\DNAJC18, Hsap\DNAJB1, Hsap\DNAJB12, Hsap\DNAJB9" "viable,fertile" DRSC26191 K -0.324679816 0.289097165 0.201279652 -0.285264351 -0.623457305 -2.252401078 FBgn0052105 Lmx1a LIM homeobox transcription factor 1 alpha http://flybase.org/reports/FBgn0052105 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG17615, CG10432, CG32105, Lmx1a, dLmx1a" "IPR001356:Homeobox domain, IPR001781:Zinc finger, LIM-type, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site" CG32105 11-Aug-17 DroID_v2017_08 "Drer\lmx1a, Drer\pou3f3b, Drer\zgc:195282, Drer\hoxa9b, Drer\lmx1ba, Drer\pou3f2b, Drer\lmx1bb, Drer\lmx1al, Drer\hoxb7a, Drer\pou3f1" Scer\YOX1 "Cele\php-3, Cele\lim-6, Cele\ceh-6" "Xtro\lmx1a, Xtro\hoxa7, Xtro\lmx1b.1, Xtro\pou3f1, Xtro\lmx1b.2" "Mmus\Pou3f4, Mmus\Pou3f3, Mmus\Lmx1a, Mmus\Hoxb7, Mmus\Pou3f2, Mmus\Lmx1b, Mmus\Pou3f1, Mmus\Hoxa7" "Hsap\POU3F3, Hsap\HOXA7, Hsap\POU3F2, Hsap\LMX1B, Hsap\HOXB7, Hsap\POU3F1, Hsap\LMX1A, Hsap\POU3F4" FBgn0040666 CG12848 - http://flybase.org/reports/FBgn0040666 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrial translation ; GO:0032543 | inferred from electronic annotation with InterPro:IPR033620 biological_process ; GO:0008150 | no biological data available mitochondrial ribosome ; GO:0005761 | inferred from electronic annotation with InterPro:IPR033620 cellular_component ; GO:0005575 | no biological data available CG12848 "IPR010625:CHCH, IPR009069:Cysteine alpha-hairpin motif superfamily, IPR033620:Coiled-coil-helix-coiled-coil-helix domain-containing protein 1" CG12848 11-Aug-17 DroID_v2017_08 Drer\chchd1 - Cele\C24D10.6 Xtro\chchd1 Mmus\Chchd1 Hsap\CHCHD1 "partially lethal - majority die,visible" "chaeta,supernumerary" FBgn0036142 CG7616 - http://flybase.org/reports/FBgn0036142 protein_coding_gene - mitochondrion organization ; GO:0007005 | inferred from sequence or structural similarity with SGD:S000004243 lipid homeostasis ; GO:0055088 | inferred from sequence or structural similarity with SGD:S000004243 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with SGD:S000004243 "CG7616, FBgn 36142" "IPR004147:UbiB domain, IPR011009:Protein kinase-like domain" CG7616 11-Aug-17 DroID_v2017_08 "Drer\adck5, Drer\adck1" Scer\MCP2 Cele\D2023.6 Xtro\adck1 "Mmus\Adck1, Mmus\Adck5" "Hsap\ADCK1, Hsap\ADCK5" viable FBgn0028605 l(2)W2 lethal (2) W2 http://flybase.org/reports/FBgn0028605 gene - - - "l(2R)W2, l(2)W2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031774 CG9147 - http://flybase.org/reports/FBgn0031774 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR016039 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR016039 - CG9147 "IPR016039:Thiolase-like, IPR008554:Glutaredoxin-like, IPR012336:Thioredoxin-like fold" CG9147 11-Aug-17 DroID_v2017_08 Drer\si:dkey-184a18.5 Scer\YDR286C - - Mmus\C330018D20Rik Hsap\C5orf63 "viable,fertile,visible" trichogen cell FBgn0003746 tre triangle eye http://flybase.org/reports/FBgn0003746 - gene - - - tre - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,viable,male fertile,visible" "wing,eye" FBgn0266022 CR44787 - http://flybase.org/reports/FBgn0266022 non_protein_coding_gene - - - "CR44787, lincRNA.12" - CR44787 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026397 Or22b Odorant receptor 22b http://flybase.org/reports/FBgn0026397 - protein_coding_gene "odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | non-traceable author statement inferred by curator from GO:0004888,GO:0007608 transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402" sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 sensory perception of smell ; GO:0007608 | inferred from expression pattern integral component of membrane ; GO:0016021 | inferred from sequence model dendrite ; GO:0030425 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | non-traceable author statement "Or22b, 22b, DOR22b, DOR67, CG4231, AN12, 22A.2, DOR22A.2, Dor67, dor67, Or67, Or22A.2, OR22b, dOr22b, Or22a/b, or22b, Or22" "IPR023298:P-type ATPase, transmembrane domain, IPR004117:Olfactory receptor, insect" CG4231 11-Aug-17 DroID_v2017_08 - - - - - - adult stage sensory neuron &&of antennal segment 3

FBgn0040758 CG13166 - http://flybase.org/reports/FBgn0040758 protein_coding_gene - - - CG13166 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035217 FucTD FucTD http://flybase.org/reports/FBgn0035217 protein_coding_gene alpha-(1->3)-fucosyltransferase activity ; GO:0046920 | inferred from biological aspect of ancestor with PANTHER:PTN000231531 protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR001503 Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000231531 "CG9169, FucTD" "IPR001503:Glycosyl transferase family 10, IPR031481:Fucosyltransferase, N-terminal" CG9169 11-Aug-17 DroID_v2017_08 "Drer\zgc:136963, Drer\zgc:165519, Drer\ft2, Drer\ft1, Drer\zgc:103510, Drer\fut9d, Drer\ctu1, Drer\fut9b, Drer\fut11, Drer\zgc:165582, Drer\si:ch1073-440p11.2, Drer\fut7, Drer\fut9a, Drer\zgc:112433, Drer\zgc:173737, Drer\fut10" - "Cele\fut-3, Cele\C07E3.8, Cele\fut-5, Cele\fut-1" "Xtro\fut4, Xtro\fut3, Xtro\fut11, Xtro\fut9, Xtro\fut10, Xtro\fut6" "Mmus\Fut7, Mmus\Fut11, Mmus\Fut10, Mmus\Fut9, Mmus\Fut4" "Hsap\FUT11, Hsap\FUT4, Hsap\FUT6, Hsap\FUT10, Hsap\FUT3, Hsap\FUT7, Hsap\FUT9, Hsap\FUT5" viable FBgn0005590 scw screw http://flybase.org/reports/FBgn0005590 "FBgn0002053, FBgn0003343, FBgn0046219, FBgn0051695" protein_coding_gene "growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR001111, InterPro:IPR001839, InterPro:IPR017948 transforming growth factor beta receptor binding ; GO:0005160 | traceable author statement cytokine activity ; GO:0005125 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:P07713" "dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement dorsal/ventral pattern formation ; GO:0009953 | traceable author statement regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | non-traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from direct assay amnioserosa formation ; GO:0007378 | non-traceable author statement positive regulation of pathway-restricted SMAD protein phosphorylation ; GO:0010862 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 BMP signaling pathway ; GO:0030509 | non-traceable author statement gonad development ; GO:0008406 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement cell fate specification ; GO:0001708 | non-traceable author statement regulation of MAPK cascade ; GO:0043408 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 SMAD protein signal transduction ; GO:0060395 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 cell development ; GO:0048468 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 digestive tract mesoderm development ; GO:0007502 | inferred from mutant phenotype BMP signaling pathway ; GO:0030509 | inferred from biological aspect of ancestor with PANTHER:PTN000218210" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with dpp "Scw, l(2)37Ff, CG31695, l(2)IG76, BcDNA:LD30945, scw, SCW, mor2" "IPR001111:TGF-beta, propeptide, IPR001839:Transforming growth factor-beta, C-terminal, IPR015615:Transforming growth factor-beta-related, IPR017948:Transforming growth factor beta, conserved site, IPR029034:Cystine-knot cytokine" CG31695 11-Aug-17 DroID_v2017_08 "Drer\bmp10l, Drer\inhbaa, Drer\LOC100329520, Drer\bmp7a, Drer\tgfb2, Drer\lft2, Drer\gdf2, Drer\bmp2a, Drer\bmp4, Drer\gdf11, Drer\bmp8a, Drer\tgfb2l, Drer\bmp10, Drer\gdf5, Drer\amh, Drer\bmp2b, Drer\bmp7b, Drer\inhbb, Drer\admp, Drer\tgfb1b, Drer\inhbab, Drer\gdf10a, Drer\spaw, Drer\inha, Drer\ndr1, Drer\ndr2, Drer\gdf10b, Drer\gdf6a, Drer\bmp5, Drer\gdf3, Drer\bmp15, Drer\tgfb3, Drer\bmp3, Drer\mstna, Drer\gdf9, Drer\bmp6, Drer\lft1, Drer\gdf7, Drer\mstnb, Drer\tgfb1a, Drer\gdf6b" - "Cele\tig-2, Cele\unc-129, Cele\daf-7, Cele\dbl-1" "Xtro\bmp2, Xtro\gdf3, Xtro\bmp7.2, Xtro\bmp3, Xtro\admp, Xtro\nodal6, Xtro\bmp10, Xtro\nodal1, Xtro\tgfb1, Xtro\gdf11.1, Xtro\gdf7, Xtro\bmp4, Xtro\bmp8, Xtro\bmp6, Xtro\gdf10, Xtro\bmp5, Xtro\gdf2, Xtro\gdf1, Xtro\inhbc.1, Xtro\gdf5, Xtro\nodal, Xtro\gdf9, Xtro\tgfb2, Xtro\bmp7.1, Xtro\nodal, Xtro\bmp15, Xtro\lefty, Xtro\nodal5, Xtro\inha, Xtro\mstn.1" "Mmus\Bmp8b, Mmus\Bmp10, Mmus\Lefty1, Mmus\Mstn, Mmus\Bmp6, Mmus\Lefty2, Mmus\Gdf11, Mmus\Gdf10, Mmus\Bmp7, Mmus\Gdf5, Mmus\Bmp8a, Mmus\Gdf15, Mmus\Inha, Mmus\Bmp4, Mmus\Inhba, Mmus\Gdf9, Mmus\Bmp2, Mmus\Gdf3, Mmus\Inhbb, Mmus\Tgfb2, Mmus\Gdf1, Mmus\Gdf7, Mmus\Bmp5, Mmus\Bmp15, Mmus\Inhbc, Mmus\Nodal, Mmus\Gdf2, Mmus\Amh, Mmus\Inhbe, Mmus\Gdf6, Mmus\Tgfb3, Mmus\Tgfb1, Mmus\Bmp3, Mmus\Cers1" "Hsap\GDF15, Hsap\BMP6, Hsap\TGFB2, Hsap\TGFB3, Hsap\INHBE, Hsap\BMP5, Hsap\MSTN, Hsap\GDF9, Hsap\INHBB, Hsap\GDF11, Hsap\GDF2, Hsap\BMP4, Hsap\BMP3, Hsap\AMH, Hsap\GDF10, Hsap\GDF7, Hsap\BMP10, Hsap\GDF6, Hsap\INHBC, Hsap\BMP8B, Hsap\INHA, Hsap\BMP7, Hsap\GDF3, Hsap\GDF5, Hsap\BMP8A, Hsap\GDF1, Hsap\LEFTY1, Hsap\CERS1, Hsap\INHBA, Hsap\TGFB1, Hsap\BMP15, Hsap\LEFTY2, Hsap\NODAL, Hsap\BMP2" " embryonic stage , embryonic stage | 2-4 hr , embryonic stage | stage 4 " "wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,visible,partially lethal - majority die,some die during pupal stage,circadian rhythm defective,heat sensitive" "gonad,visceral mesoderm,crystal cell,embryonic leading edge cell,embryo,dorsal,cephalic furrow,embryonic/larval spiracle,posterior,denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,filzkorper,amnioserosa,embryonic/larval dorsal vessel,cephalopharyngeal skeleton,abdomen,extended germ band embryo,dorsal ectoderm,stage 14 embryo,embryonic/larval posterior spiracle,wing vein,ectopic,wing,compartment,distal" FBgn0004011 wgv wing variance http://flybase.org/reports/FBgn0004011 - gene - - - wgv - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male sterile,viable,male" wing FBgn0004440 prd5 paired-like 5 http://flybase.org/reports/FBgn0004440 - gene - - - prd5 - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | early FBgn0032067 LManIV Lysosomal alpha-mannosidase IV http://flybase.org/reports/FBgn0032067 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR015341 alpha-mannosidase activity ; GO:0004559 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 protein deglycosylation ; GO:0006517 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 mannose metabolic process ; GO:0006013 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 - "CG9465, LManIV" "IPR000602:Glycoside hydrolase family 38, N-terminal domain, IPR011013:Galactose mutarotase-like domain, IPR011682:Glycosyl hydrolase family 38, C-terminal, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR015341:Glycoside hydrolase family 38, central domain, IPR027291:Glycoside hydrolase 38/57, N-terminal domain, IPR028995:Glycoside hydrolase families 57/38, central domain" CG9465 11-Aug-17 DroID_v2017_08 "Drer\man2b2, Drer\man2a2, Drer\man2b1" - Cele\aman-1 "Xtro\man2b1, Xtro\man2b2, Xtro\man2a2, Xtro\man2a1" "Mmus\Man2b1, Mmus\Man2b2, Mmus\Man2a1" "Hsap\MAN2B2, Hsap\MAN2B1, Hsap\MAN2A1, Hsap\MAN2A2" FBgn0277418 l(3)psg28 - http://flybase.org/reports/FBgn0277418 gene - - - "l(3)psg28, psg28" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067332 su(Hw)BR-y-AS-C suppressor of Hairy wing Binding Region in the yellow achaete-scute region http://flybase.org/reports/FBgn0067332 insulator - - - "1A-2, su(Hw)BR-y-AS-C, 1A2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260943 Rbp6 RNA-binding protein 6 http://flybase.org/reports/FBgn0260943 protein_coding_gene single-stranded RNA binding ; GO:0003727 | inferred from sequence or structural similarity with UniProtKB:Q920Q6 poly(U) RNA binding ; GO:0008266 | inferred from sequence or structural similarity with UniProtKB:Q920Q6 stem cell development ; GO:0048864 | inferred from sequence or structural similarity with UniProtKB:Q920Q6 polysome ; GO:0005844 | inferred from sequence or structural similarity with UniProtKB:Q920Q6 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q920Q6 "Rbp6, rbp6, RRM6, rrm6, BcDNA:RE25373, CG6573, CG14056, CG14055, CG32169" "IPR000504:RNA recognition motif domain, IPR034126:RNA-binding protein Musashi homologue, RNA recognition motif 2, IPR034130:RNA-binding protein Musashi homologue, RNA recognition motif 1" CG32169 11-Aug-17 DroID_v2017_08 "Drer\hnrnpabb, Drer\msi2a, Drer\msi2b, Drer\hnrnpaba, Drer\hnrnpa0l, Drer\LOC100537556, Drer\hnrnpa1a, Drer\zgc:110796, Drer\dazap1, Drer\hnrnpd, Drer\hnrpdl, Drer\msi1, Drer\hnrnpa1b, Drer\hnrnpa3, Drer\hnrnpa0b, Drer\hnrnpa0a" Scer\HRP1 "Cele\H28G03.1, Cele\msi-1" "Xtro\msi2, Xtro\hnrnpa2b1, Xtro\hnrnpd, Xtro\hnrnpa3, Xtro\hnrnpab, Xtro\hnrnpa1, Xtro\hnrnpa0, Xtro\dazap1, Xtro\hnrnpdl, Xtro\msi1" "Mmus\Msi1, Mmus\Hnrnpa2b1, Mmus\Dazap1, Mmus\Msi2, Mmus\Hnrnpd, Mmus\Hnrnpa0, Mmus\Rbm31y, Mmus\Hnrnpa3, Mmus\Hnrnpab, Mmus\Hnrnpa1, Mmus\Hnrnpdl" "Hsap\HNRNPAB, Hsap\HNRNPA1, Hsap\HNRNPA0, Hsap\HNRNPA2B1, Hsap\HNRNPDL, Hsap\HNRNPA3, Hsap\HNRNPA1L2, Hsap\DAZAP1, Hsap\MSI1, Hsap\MSI2, Hsap\HNRNPD" FBgn0266617 CR45124 - http://flybase.org/reports/FBgn0266617 non_protein_coding_gene - - - CR45124 - CR45124 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004498 fs(1)gammab4 female sterile (1) gammab4 http://flybase.org/reports/FBgn0004498 - gene - - - fs(1)gammab4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005454 l(1)v361 lethal (1) v361 http://flybase.org/reports/FBgn0005454 - gene - - - "l(1)361, l(1)v361" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030425 CG3775 - http://flybase.org/reports/FBgn0030425 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "neuropeptide signaling pathway ; GO:0007218 | inferred from electronic annotation with InterPro:IPR029736 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - "BEST:GH06882, CG3775" "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR029736:Endothelin-converting enzyme-like 1" CG3775 11-Aug-17 DroID_v2017_08 "Drer\ece1, Drer\phex, Drer\mmel1, Drer\ece2b" - "Cele\nep-17, Cele\nep-12, Cele\nep-8, Cele\nep-24, Cele\nep-6, Cele\nep-18, Cele\nep-9, Cele\nep-5, Cele\nep-10, Cele\nep-13, Cele\nep-26, Cele\nep-20, Cele\nep-7, Cele\nep-3, Cele\nep-19, Cele\nep-16, Cele\nep-23, Cele\nep-21" "Xtro\mmel1, Xtro\ece2, Xtro\ecel1, Xtro\ece1" "Mmus\Ece1, Mmus\Mme, Mmus\Phex, Mmus\Kel, Mmus\Ece2, Mmus\Mmel1, Mmus\Ecel1" "Hsap\PHEX, Hsap\ECE2, Hsap\ECE1, Hsap\MMEL1, Hsap\ECEL1, Hsap\KEL, Hsap\MME" DRSC19877 E -1.088592964 -1.224050489 -2.377314715 -2.825609375 0.242347627 0.695108768 FBgn0053987 CR33987 - http://flybase.org/reports/FBgn0053987 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CR33987 - CR33987 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051580 tRNA:Ala-AGC-2-8 transfer RNA:Alanine-AGC 2-8 http://flybase.org/reports/FBgn0051580 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna44-AlaAGC, tRNA:A:AGC:AE002708-h, CR31580, tRNA[[Ala]], chr3R.trna50-AlaAGC, tRNA-Ala-AGC-2-8, tRNA:Ala-AGC-2-8, tRNA:CR31580, GCU" - CR31580 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005325 NX Notch Xasta http://flybase.org/reports/FBgn0005325 - gene - - - NX - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040129 l(2)22Aj lethal (2) 22Aj http://flybase.org/reports/FBgn0040129 gene - - - "E, l(2)22Aj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0070019 BG01046 BG01046 http://flybase.org/reports/FBgn0070019 gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - BG01046 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,behavior defective,recessive" FBgn0044126 E(rst)B246 E(rst)B246 http://flybase.org/reports/FBgn0044126 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B246, E(rst)B246" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036553 CG17027 - http://flybase.org/reports/FBgn0036553 protein_coding_gene inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from sequence or structural similarity with HGNC:6051 inositol monophosphate 1-phosphatase activity ; GO:0008934 | non-traceable author statement inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550, InterPro:IPR020552 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol metabolic process ; GO:0006020 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol phosphate dephosphorylation ; GO:0046855 | inferred from sequence or structural similarity with HGNC:6051 dephosphorylation ; GO:0016311 | non-traceable author statement inositol phosphate dephosphorylation ; GO:0046855 | inferred from biological aspect of ancestor with PANTHER:PTN000465134" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6051 "152392_at, IMP, CG17027" "IPR000760:Inositol monophosphatase-like, IPR033942:Inositol monophosphatase, IPR020550:Inositol monophosphatase, conserved site, IPR020552:Inositol monophosphatase, Lithium-sensitive, IPR020583:Inositol monophosphatase, metal-binding site" CG17027 11-Aug-17 DroID_v2017_08 "Drer\impa1, Drer\impa2" "Scer\INM1, Scer\INM2" Cele\ttx-7 "Xtro\impa2, Xtro\impa1" "Mmus\Impa2, Mmus\Impa1" "Hsap\IMPA2, Hsap\IMPA1" "partially lethal - majority die,some die during pupal stage,viable" FBgn0002452 l(3)SG5 lethal (3) SG5 http://flybase.org/reports/FBgn0002452 - gene - - - l(3)SG5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0265187 CG44252 - http://flybase.org/reports/FBgn0265187 protein_coding_gene very long-chain fatty acid-CoA ligase activity ; GO:0031957 | inferred from sequence or structural similarity with UniProtKB:Q60714 fatty acid transporter activity ; GO:0015245 | inferred from sequence or structural similarity with UniProtKB:Q60714 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 fatty acid transport ; GO:0015908 | inferred from sequence or structural similarity with UniProtKB:Q60714 integral component of membrane ; GO:0016021 | inferred from sequence model "CG30194, CG44252" "IPR025110:AMP-binding enzyme C-terminal domain, IPR020845:AMP-binding, conserved site, IPR000873:AMP-dependent synthetase/ligase" CG44252 11-Aug-17 DroID_v2017_08 "Drer\slc27a2a, Drer\LOC568883, Drer\slc27a1b, Drer\slc27a4, Drer\slc27a2b, Drer\zgc:158482, Drer\slc27a6, Drer\slc27a1a" Scer\FAT1 "Cele\acs-22, Cele\acs-20" "Xtro\slc27a2, Xtro\slc27a3, Xtro\slc27a6, Xtro\slc27a4" "Mmus\Slc27a1, Mmus\Slc27a2, Mmus\Slc27a5, Mmus\Slc27a3, Mmus\Slc27a4, Mmus\Slc27a6" "Hsap\SLC27A5, Hsap\SLC27A3, Hsap\SLC27A2, Hsap\SLC27A4, Hsap\SLC27A6, Hsap\SLC27A1" "viable,fertile" FBgn0001445 l(1)7Cg lethal (1) 7Cg http://flybase.org/reports/FBgn0001445 - gene - - - l(1)7Cg - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0060425 l(3)S126711 lethal (3) S126711 http://flybase.org/reports/FBgn0060425 gene - - - "1267/11, l(3)S126711" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040192 l(1)G0185 lethal (1) G0185 http://flybase.org/reports/FBgn0040192 gene - - - l(1)G0185 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260105 2L4771 - http://flybase.org/reports/FBgn0260105 gene - - - 2L4771 - - 11-Aug-17 DroID_v2017_08 - - - - - - "tracheal fusion cell,somatic clone,embryonic/larval dorsal trunk" FBgn0265794 CR44583 - http://flybase.org/reports/FBgn0265794 non_protein_coding_gene - - - "lincRNA.105, CR44583" - CR44583 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032618 CG31743 - http://flybase.org/reports/FBgn0032618 protein_coding_gene sulfotransferase activity ; GO:0008146 | inferred from sequence or structural similarity with MGI:MGI:2138283 carbohydrate biosynthetic process ; GO:0016051 | inferred from electronic annotation with InterPro:IPR018011 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR018011" "152851_at, CG4826, CG31743, dC4ST" "IPR005331:Sulfotransferase, IPR018011:Carbohydrate sulfotransferase 8-10" CG31743 11-Aug-17 DroID_v2017_08 "Drer\chst14, Drer\si:dkey-26i13.3, Drer\LOC100536144, Drer\si:ch211-236h17.3, Drer\chst10, Drer\chst12b, Drer\si:dkey-26i13.6, Drer\si:ch211-269c21.2, Drer\si:dkey-26i13.5, Drer\chst11, Drer\si:dkey-26i13.4, Drer\chst12a, Drer\si:dkey-26i13.7, Drer\chst8" - "Cele\F59D12.3, Cele\Y87G2A.16, Cele\C41C4.1, Cele\C18B2.2, Cele\F17B5.4, Cele\F55B12.2, Cele\F56H6.13, Cele\C31B8.9, Cele\T09E11.3, Cele\C18B2.1, Cele\K07H8.8, Cele\F25E5.2, Cele\F01D5.10" "Xtro\chst13, Xtro\chst11, Xtro\chst8, Xtro\chst14, Xtro\chst12" "Mmus\Chst10, Mmus\Chst14, Mmus\Chst12, Mmus\Chst13, Mmus\Chst11, Mmus\Chst8, Mmus\Chst9" "Hsap\CHST11, Hsap\CHST13, Hsap\CHST9, Hsap\CHST14, Hsap\CHST12, Hsap\CHST10, Hsap\CHST8" FBgn0060755 l(3)SzB72Ca lethal (3) SzB72Ca http://flybase.org/reports/FBgn0060755 gene - - - "0643/01, l(3)S064301a, l(3)SzB72Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263959 BG01540 - http://flybase.org/reports/FBgn0263959 gene - - - BG01540 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,male limited" FBgn0001553 l(1)19Ac lethal (1) 19Ac http://flybase.org/reports/FBgn0001553 - gene - - - "EM19, l(1)EM19, l(1)19Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040260 Ugt36Bc Ugt36Bc http://flybase.org/reports/FBgn0040260 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG17932, AC 005121C, Ugt36Bc" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG17932 11-Aug-17 DroID_v2017_08 "Drer\ugt5c3, Drer\ugt5d1, Drer\ugt5b2, Drer\ugt5a5, Drer\ugt1ab, Drer\ugt1b4, Drer\ugt5b6, Drer\ugt5b3, Drer\ugt5b1, Drer\ugt5g1, Drer\ugt2a2, Drer\ugt5f1, Drer\ugt5c2, Drer\ugt2b1, Drer\ugt1b2, Drer\ugt5e1, Drer\ugt1b5, Drer\ugt1b3, Drer\ugt2b3, Drer\ugt5a1, Drer\zgc:172315, Drer\ugt5a2, Drer\ugt2a5, Drer\ugt2b6, Drer\ugt5c1, Drer\ugt5a4, Drer\ugt8, Drer\ugt5g2, Drer\ugt2b5, Drer\ugt2a6, Drer\ugt1b7" Scer\ATG26 "Cele\H23N18.4, Cele\ugt-44, Cele\F10D2.8, Cele\ugt-35, Cele\ugt-10, Cele\ugt-9, Cele\ugt-57, Cele\ugt-22, Cele\C03A7.13, Cele\ugt-52, Cele\ugt-3, Cele\ugt-37, Cele\ugt-56, Cele\ugt-49, Cele\ugt-40, Cele\ugt-29, Cele\ugt-31, Cele\ugt-6, Cele\ugt-18, Cele\ugt-38, Cele\ugt-19, Cele\ugt-54, Cele\ugt-55, Cele\ugt-11, Cele\ugt-58, Cele\ugt-32, Cele\ugt-5, Cele\ugt-50, Cele\ugt-1, Cele\ugt-21, Cele\ugt-53, Cele\ugt-43, Cele\ugt-30, Cele\ugt-48, Cele\ugt-47, Cele\ugt-23, Cele\ugt-59, Cele\ugt-39, Cele\ugt-13, Cele\ugt-26, Cele\ugt-24, Cele\ugt-51, Cele\ugt-12, Cele\ugt-60, Cele\K04A8.10, Cele\ugt-41, Cele\ugt-62, Cele\ugt-34, Cele\C55H1.1, Cele\ugt-20, Cele\ugt-36, Cele\C03A7.12, Cele\ugt-27, Cele\ugt-7, Cele\ugt-16, Cele\ugt-2, Cele\ugt-46, Cele\ugt-8, Cele\ugt-61, Cele\ugt-17, Cele\ugt-15, Cele\ugt-4, Cele\ugt-28, Cele\ugt-45, Cele\ugt-33, Cele\ugt-25, Cele\ugt-42, Cele\ugt-63, Cele\C23G10.6, Cele\ugt-14, Cele\Y43D4A.2" "Xtro\ugt8, Xtro\ugt2a1, Xtro\ugt3a2, Xtro\ugt1a6, Xtro\ugt2b4" "Mmus\Ugt2b5, Mmus\Ugt2a1, Mmus\Ugt1a1, Mmus\Ugt2b1, Mmus\Ugt2b34, Mmus\Ugt1a6b, Mmus\Ugt1a9, Mmus\Ugt2b35, Mmus\Ugt2b38, Mmus\Ugt1a5, Mmus\Ugt1a2, Mmus\Ugt2b37, Mmus\Ugt2b36, Mmus\Ugt2a3, Mmus\Ugt3a1, Mmus\Ugt8a, Mmus\Ugt3a2, Mmus\Ugt1a7c" "Hsap\UGT3A2, Hsap\UGT2A3, Hsap\UGT1A8, Hsap\UGT1A3, Hsap\UGT2B11, Hsap\UGT1A4, Hsap\UGT2A2, Hsap\UGT1A9, Hsap\UGT1A10, Hsap\UGT2B28, Hsap\UGT2B10, Hsap\UGT1A1, Hsap\UGT1A6, Hsap\UGT2B15, Hsap\UGT8, Hsap\UGT2B7, Hsap\UGT2B4, Hsap\UGT2B17, Hsap\UGT1A5, Hsap\UGT1A7, Hsap\UGT3A1" viable FBgn0267355 3L-079 - http://flybase.org/reports/FBgn0267355 nuclear_gene - - - "3L-079, Gene_3L_079" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027619 eIF3j eukaryotic translation initiation factor 3 subunit j http://flybase.org/reports/FBgn0027619 "FBgn0015482, FBgn0019724, FBgn0021866, FBgn0033470" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VSS1 translation initiation factor activity ; GO:0003743 | inferred from direct assay translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translational initiation ; GO:0006413 | inferred from sequence or structural similarity regulation of translational initiation ; GO:0006446 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000495261 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity "CG12131, l(2)k13906, 5.3, E, eIF3-S1, l(2)46CFd, l(2)46Cf, Q7K550_DROME, eIF3j, Adam" "IPR013906:Eukaryotic translation initiation factor 3 subunit J, IPR023194:Eukaryotic translation initiation factor 3-like domain" CG12131 11-Aug-17 DroID_v2017_08 "Drer\eif3jb, Drer\eif3ja" Scer\HCR1 Cele\eif-3.J Xtro\eif3j "Mmus\Eif3j1, Mmus\Eif3j2" Hsap\EIF3J "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0032665 CG15152 - http://flybase.org/reports/FBgn0032665 protein_coding_gene - - - CG15152 - CG15152 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02453 K 0.024429725 0.104622304 -0.131175012 0.404384924 2.023839882 0.561828373 FBgn0267685 CR46021 - http://flybase.org/reports/FBgn0267685 non_protein_coding_gene - - - CR46021 - CR46021 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065828 l(2)SH0355 lethal (2) SH0355 http://flybase.org/reports/FBgn0065828 gene - - - "l(2)SH0355, l(2)SH2 0355" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013660 ms(2)neo5 ms(2)neo5 http://flybase.org/reports/FBgn0013660 - gene - - - ms(2)neo5 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0262475 bru2 bruno 2 http://flybase.org/reports/FBgn0262475 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 RNA binding ; GO:0003723 | inferred from sequence alignment with bru1 negative regulation of translation ; GO:0017148 | inferred from sequence alignment with bru1 cellular_component ; GO:0005575 | no biological data available "CG43065, CG17008, Dm Bru-2, CG6319, CG31761, Bru-2, CG31763, bru-2, bru2" "IPR034196:CELF1/2, RNA recognition motif 1, IPR000504:RNA recognition motif domain" CG43065 11-Aug-17 DroID_v2017_08 "Drer\celf3a, Drer\celf4, Drer\celf3b, Drer\celf1, Drer\celf2, Drer\celf5a, Drer\si:dkey-205h23.2" Scer\GBP2 "Cele\unc-75, Cele\etr-1" "Xtro\celf2, Xtro\celf5, Xtro\celf1, Xtro\celf4, Xtro\celf3" "Mmus\Celf3, Mmus\Celf5, Mmus\Celf2, Mmus\Celf1, Mmus\Celf6, Mmus\Celf4" "Hsap\CELF6, Hsap\CELF4, Hsap\CELF5, Hsap\CELF3, Hsap\CELF1, Hsap\CELF2" """DRSC01247, DRSC01246"" " IEK FBgn0263398 CG6364 - http://flybase.org/reports/FBgn0263398 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006083 uridine kinase activity ; GO:0004849 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine nucleobase metabolic process ; GO:0006206 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine nucleoside salvage ; GO:0043097 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 phagocytosis ; GO:0006909 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 "CG6364, Uck2, CR42873" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000764:Uridine kinase-like, IPR006083:Phosphoribulokinase/uridine kinase" CG6364 11-Aug-17 DroID_v2017_08 "Drer\uckl1a, Drer\uprt, Drer\uck2a, Drer\uck1, Drer\si:ch211-243j20.2, Drer\uck2b, Drer\uckl1b" "Scer\DAS2, Scer\FUR1, Scer\URK1" "Cele\B0001.4, Cele\F19B6.1, Cele\C47B2.2" "Xtro\uck1, Xtro\uck2" "Mmus\Uck2, Mmus\Uck1, Mmus\Uckl1, Mmus\Uprt" "Hsap\UCK2, Hsap\UCK1, Hsap\UPRT, Hsap\UCKL1" FBgn0259598 B0469 - http://flybase.org/reports/FBgn0259598 gene - - - B0469 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,sterile" "submarginal cell,wing cell,tarsal segment,antennal segment,wing" FBgn0019728 l(2)148 lethal (2) 148 http://flybase.org/reports/FBgn0019728 - gene - - - l(2)148 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033874 CG6347 - http://flybase.org/reports/FBgn0033874 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 CG6347 "IPR025660:Cysteine peptidase, histidine active site, IPR000668:Peptidase C1A, papain C-terminal, IPR013128:Peptidase C1A, IPR013201:Cathepsin propeptide inhibitor domain (I29)" CG6347 11-Aug-17 DroID_v2017_08 "Drer\ctslb, Drer\si:dkey-269i1.4, Drer\ctss2.2, Drer\si:dkey-239j18.3, Drer\ctss2.1, Drer\ctso, Drer\LOC100536033, Drer\ctsk, Drer\zgc:174153, Drer\si:dkey-267n13.1, Drer\ctsz, Drer\wu:fa26c03, Drer\si:dkey-228a15.1, Drer\ctsbb, Drer\ctsll, Drer\ctsc, Drer\ctsla, Drer\si:dkey-269i1.3, Drer\zgc:110239, Drer\MGC174155, Drer\ctss1, Drer\zgc:174855, Drer\si:dkey-239j18.2, Drer\ctsl.1, Drer\ctsh, Drer\cts12, Drer\MGC174857, Drer\si:dkey-26g8.4, Drer\zgc:103438, Drer\si:dkey-183k8.2, Drer\LOC100333521, Drer\ctsba" - "Cele\cpl-1, Cele\cpz-1, Cele\cpz-2" "Xtro\LOC100498238, Xtro\ctsz, Xtro\ctsw, Xtro\ctsc, Xtro\ctsb, Xtro\ctsv, Xtro\ctss, Xtro\ctsh, Xtro\LOC100490139, Xtro\ctsl" "Mmus\Ctsh, Mmus\Ctsc, Mmus\Ctsb, Mmus\Ctsm, Mmus\BC051665, Mmus\Cts8, Mmus\4930486L24Rik, Mmus\Ctso, Mmus\Ctsr, Mmus\Ctsll3, Mmus\Ctsl, Mmus\Ctla2a, Mmus\Ctla2b, Mmus\Ctsk, Mmus\Ctsw, Mmus\Cts6, Mmus\Ctsj, Mmus\Cts3, Mmus\Ctsz, Mmus\Cts7, Mmus\Ctss, Mmus\Ctsq" "Hsap\CTSK, Hsap\CTSH, Hsap\CTSL, Hsap\CTSV, Hsap\CTSS, Hsap\CTSC, Hsap\CTSW, Hsap\CTSO, Hsap\CTSZ, Hsap\CTSB" "viable,fertile" FBgn0265299 CR44272 - http://flybase.org/reports/FBgn0265299 non_protein_coding_gene - - - CR44272 - CR44272 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085426 Rgk3 "Rad, Gem/Kir family member 3" http://flybase.org/reports/FBgn0085426 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTPase activity ; GO:0003924 | inferred from sequence model GTP binding ; GO:0005525 | inferred from sequence model" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 negative regulation of voltage-gated calcium channel activity ; GO:1901386 | inferred from direct assay small GTPase mediated signal transduction ; GO:0007264 | inferred from sequence model membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cytoplasmic side of plasma membrane ; GO:0009898 | inferred from sequence model "CG34397, CG15663, CG15664, CG33949, Rgk3, CG15660, mdcds_15683, mdcds_15673, RGK3" "IPR001806:Small GTPase superfamily, IPR020849:Small GTPase superfamily, Ras type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG34397 11-Aug-17 DroID_v2017_08 "Drer\mras, Drer\rheb, Drer\si:dkeyp-59c12.1, Drer\rasl12, Drer\rap1ab, Drer\ralbb, Drer\LOC100332969, Drer\rap1aa, Drer\diras1a, Drer\rras2, Drer\ralaa, Drer\ralba, Drer\gem, Drer\zgc:64022, Drer\rap2c, Drer\si:dkey-27j5.5, Drer\hrasb, Drer\si:ch73-116o1.2, Drer\rit1, Drer\rap2b, Drer\rasd1, Drer\hrasa, Drer\rhebl1, Drer\zgc:110699, Drer\rerglb, Drer\rasl10a, Drer\rrad, Drer\rem1, Drer\zgc:152698, Drer\rap2ab, Drer\kras, Drer\rem2, Drer\rras, Drer\rsg1, Drer\zgc:114118, Drer\nras, Drer\rasl11a, Drer\zgc:153845, Drer\diras2, Drer\zgc:171704, Drer\ralab, Drer\diras1b, Drer\rasl11b, Drer\rergla" "Scer\RAS1, Scer\RAS2, Scer\RHB1, Scer\RSR1" "Cele\F20D6.8, Cele\W04C9.5, Cele\Y52B11A.4" "Xtro\ralb, Xtro\rap2a, Xtro\rit1, Xtro\rheb, Xtro\rem1, Xtro\rap1a, Xtro\gem, Xtro\rasd1, Xtro\rem2, Xtro\rap2c, Xtro\ras-dva, Xtro\rasd2, Xtro\rergl, Xtro\rerg, Xtro\rala, Xtro\diras1, Xtro\rasl10a, Xtro\rhebl1, Xtro\rap2b, Xtro\LOC733456, Xtro\diras2, Xtro\hras, Xtro\kras, Xtro\nras, Xtro\rasl11b, Xtro\diras3, Xtro\rsg1, Xtro\rrad, Xtro\rap1b" "Mmus\Rap1a, Mmus\Rsg1, Mmus\Rerg, Mmus\Rras2, Mmus\Rap2a, Mmus\Diras2, Mmus\Rap2b, Mmus\Kras, Mmus\Mras, Mmus\Diras1, Mmus\Rasd2, Mmus\Rasl10b, Mmus\Rheb, Mmus\Rasl12, Mmus\Rasl10a, Mmus\Rem1, Mmus\Gm266, Mmus\Rrad, Mmus\Rhebl1, Mmus\Rasl11a, Mmus\Rem2, Mmus\Ralb, Mmus\Hras, Mmus\Rasl11b, Mmus\Rala, Mmus\Rasd1, Mmus\Rit1, Mmus\Rras, Mmus\Eras, Mmus\Rap1b, Mmus\Rergl, Mmus\Gem, Mmus\Nras, Mmus\Rap2c, Mmus\Rit2" "Hsap\RAP2C, Hsap\RERGL, Hsap\RRAS2, Hsap\KRAS, Hsap\RASL10B, Hsap\DIRAS3, Hsap\REM2, Hsap\NRAS, Hsap\RAP1A, Hsap\GEM, Hsap\RRAD, Hsap\MRAS, Hsap\RASL11A, Hsap\RRAS, Hsap\RASD1, Hsap\RHEB, Hsap\RERG, Hsap\RALB, Hsap\RAP1B, Hsap\REM1, Hsap\RHEBL1, Hsap\RIT2, Hsap\RSG1, Hsap\RAP2A, Hsap\DIRAS2, Hsap\RASL11B, Hsap\RASL10A, Hsap\RAP2B, Hsap\RALA, Hsap\RASD2, Hsap\HRAS, Hsap\RIT1, Hsap\ERAS, Hsap\DIRAS1, Hsap\RASL12" viable FBgn0003680 ted trapped http://flybase.org/reports/FBgn0003680 - gene - - - "l(3)84Cf, ted" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0086667 snoRNA:Psi28S-3342 snoRNA:Psi28S-3342 http://flybase.org/reports/FBgn0086667 snoRNA_gene - - - "snoRNA:644, CR33787, psi28s-3342, Dm-644, snoR644, Psi28S-3342(SnoR644), snoRNA:Psi28S-3342, Psi28S-3342" - CR33787 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262321 mir-960 mir-960 stem loop http://flybase.org/reports/FBgn0262321 miRNA_gene - "regulation of feeding behavior ; GO:0060259 | inferred from genetic interaction with mir-959, mir-961, mir-962 immune response ; GO:0006955 | inferred from genetic interaction with mir-959, mir-961, mir-962" - "dme-mir-960, miR-960, 960, mir-960, CR43028" - CR43028 11-Aug-17 DroID_v2017_08 - - - - - - visible FBgn0069910 CR41100 - http://flybase.org/reports/FBgn0069910 non_protein_coding_gene - - - CR41100 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263560 mir-4987 mir-4987 stem loop http://flybase.org/reports/FBgn0263560 miRNA_gene - - - "mir-4987, dme-mir-4987, CR43545" - CR43545 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033999 CG8093 - http://flybase.org/reports/FBgn0033999 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483 lipase activity ; GO:0016298 | inferred from sequence or structural similarity" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern lipid metabolic process ; GO:0006629 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from sequence model "CG8093, CT22063" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG8093 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH1, Scer\TGL1, Scer\YEH2" "Cele\lipl-5, Cele\lipl-3, Cele\lipl-4, Cele\lipl-8, Cele\lipl-1, Cele\lipl-2, Cele\lipl-7, Cele\lipl-6" Xtro\lipa "Mmus\Lipf, Mmus\Lipo3, Mmus\Lipn, Mmus\Lipm, Mmus\Lipo4, Mmus\Lipk, Mmus\Lipo1, Mmus\Lipo2, Mmus\Lipa" "Hsap\LIPJ, Hsap\LIPK, Hsap\LIPN, Hsap\LIPF, Hsap\LIPA, Hsap\LIPM" viable FBgn0260635 Diap1 Death-associated inhibitor of apoptosis 1 http://flybase.org/reports/FBgn0260635 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 protein binding ; GO:0005515 | inferred from physical interaction with IKKε caspase binding ; GO:0089720 | inferred from physical interaction with Dcp-1 inferred from physical interaction with Drice ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Diap2 ubiquitin-specific protease binding ; GO:1990381 | inferred from physical interaction with DUBAI protein binding ; GO:0005515 | inferred from physical interaction with hid inferred from physical interaction with rpr protein binding ; GO:0005515 | inferred from physical interaction with hid inferred from physical interaction with Dcp-1 NEDD8 ligase activity ; GO:0061663 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VFJ3 cysteine-type endopeptidase inhibitor activity involved in apoptotic process ; GO:0043027 | inferred from direct assay ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with eff ubiquitin-protein transferase activity ; GO:0004842 | traceable author statement zinc ion binding ; GO:0008270 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with Jafrac2 cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from direct assay ubiquitin-like protein conjugating enzyme binding ; GO:0044390 | inferred from physical interaction with UbcE2M spermatid nucleus differentiation ; GO:0007289 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype inhibition of cysteine-type endopeptidase activity involved in apoptotic process ; GO:1990001 | inferred from mutant phenotype negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043154 | inferred from mutant phenotype inferred from genetic interaction with Dcp-1 inferred from genetic interaction with Drice apoptotic process ; GO:0006915 | traceable author statement inhibition of cysteine-type endopeptidase activity ; GO:0097340 | inferred from direct assay sensory organ precursor cell division ; GO:0045035 | inferred from genetic interaction with IKKε negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043154 | inferred from direct assay protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | traceable author statement negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043154 | traceable author statement negative regulation of apoptotic process ; GO:0043066 | traceable author statement protein K48-linked ubiquitination ; GO:0070936 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from physical interaction with hid inferred from physical interaction with rpr positive regulation of protein ubiquitination ; GO:0031398 | inferred from direct assay germ cell migration ; GO:0008354 | traceable author statement border follicle cell migration ; GO:0007298 | inferred from mutant phenotype inferred from genetic interaction with Rac1 protein autoubiquitination ; GO:0051865 | inferred from direct assay apoptotic process ; GO:0006915 | non-traceable author statement antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype multicellular organism development ; GO:0007275 | traceable author statement negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | inferred from mutant phenotype protein neddylation ; GO:0045116 | inferred from direct assay negative regulation of apoptotic process ; GO:0043066 | inferred from direct assay negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043154 | inferred from genetic interaction with Drice inferred from genetic interaction with Dronc inferred from genetic interaction with Dark negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:2001271 | inferred from direct assay protein polyubiquitination ; GO:0000209 | inferred from direct assay negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with hid inferred from genetic interaction with rpr nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "DIAP1, dIAP1, diap1, CG12284, DIAP-1, Diap1, th, Diap, Thread, l(3)72CDe, DIAPI, Diap-1, IAP, DIAP I, D-IAP1, DIAP, diap1/thread, Diap-1/Th, diap-1, dIAP, D-iap1, dIAP-1, l(3)j5C8, l(3)S030605b, 0736/01, 1065/03, l(3)72Dc, Iap1, E(rpr)3-1, l(3)S030605, l(3)S106503, IAP1, dIap1, diap, diap 1, S048915, TH, thread" "IPR001370:BIR repeat, IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG12284 11-Aug-17 DroID_v2017_08 "Drer\birc2, Drer\xiap, Drer\birc6, Drer\birc5a, Drer\birc5b, Drer\birc7" - "Cele\bir-2, Cele\bir-1, Cele\K11D12.9" "Xtro\birc7, Xtro\birc6, Xtro\xiap, Xtro\birc5.2, Xtro\nlrc4, Xtro\birc2, Xtro\birc5.1" "Mmus\Birc3, Mmus\Birc5, Mmus\Birc2, Mmus\Birc7, Mmus\Naip1, Mmus\Nlrc4, Mmus\Xiap, Mmus\Naip7, Mmus\Naip6, Mmus\Naip2, Mmus\Naip5, Mmus\Birc6" "Hsap\XIAP, Hsap\BIRC7, Hsap\BIRC5, Hsap\BIRC3, Hsap\NAIP, Hsap\BIRC2, Hsap\BIRC8, Hsap\BIRC6, Hsap\NLRC4" " embryonic stage , larval stage " "

ubiquitous , eye-antennal disc

" DRSC11404 IEK -0.43920138 -6.221428133 -2.699430873 -3.810293217 -0.584042549 16.1093693 FBgn0046647 anon-38D.2 anon-38D.2 http://flybase.org/reports/FBgn0046647 gene - - - "38D.2, anon-38D.2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260995 dpr21 defective proboscis extension response 21 http://flybase.org/reports/FBgn0260995 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern - "CG42596, dpr21, Dpr21" "IPR003598:Immunoglobulin subtype 2, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype" CG42596 11-Aug-17 DroID_v2017_08 "Drer\sdk1b, Drer\ncam1b, Drer\lrit3b, Drer\itgb4, Drer\LOC100333196, Drer\sdk1a, Drer\kirrel3b, Drer\LOC101885725, Drer\LOC101885444, Drer\igsf9bb, Drer\si:ch211-163c2.2, Drer\kirrelb, Drer\kirrel3a, Drer\ush2a, Drer\kirrel3l, Drer\igsf11, Drer\si:ch1073-459j12.1, Drer\kirrela, Drer\lrit1b, Drer\lrit1a, Drer\paplna, Drer\igsf9a, Drer\si:dkey-65b12.12, Drer\dscama, Drer\lrit3a" - Cele\zig-8 "Xtro\lrit3, Xtro\igsf9b, Xtro\papln, Xtro\kirrel2" "Mmus\Igsf11, Mmus\Lrit1, Mmus\Amica1, Mmus\Ptprq, Mmus\Kirrel2, Mmus\Sdk1, Mmus\Kirrel, Mmus\Igsf9b, Mmus\Lrit3, Mmus\Kirrel3, Mmus\Papln" "Hsap\IGSF9B, Hsap\CADM1, Hsap\CADM4, Hsap\USH2A, Hsap\LRIT3, Hsap\KIRREL2, Hsap\CADM2, Hsap\LRIT1, Hsap\CADM3, Hsap\KIRREL, Hsap\SDK1, Hsap\KIRREL3, Hsap\PAPLN" FBgn0039104 CG10252 - http://flybase.org/reports/FBgn0039104 protein_coding_gene - - prefoldin complex ; GO:0016272 | colocalizes_with inferred from direct assay "bs30h03.y1, BEST:GH13953, anon-WO0140519.133, CG10252" IPR010736:Sperm-tail PG-rich repeat CG10252 11-Aug-17 DroID_v2017_08 "Drer\odf3l2, Drer\zgc:110183, Drer\odf3b" - - "Xtro\odf3, Xtro\odf3l1" "Mmus\Odf3l1, Mmus\Odf3, Mmus\Odf3l2, Mmus\Odf3b" "Hsap\ODF3B, Hsap\ODF3, Hsap\ODF3L1, Hsap\ODF3L2" viable FBgn0036135 mRpL2 mitochondrial ribosomal protein L2 http://flybase.org/reports/FBgn0036135 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AI313184 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AI313184 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AI313184 "L2, CG7636, mRpL2" "IPR002171:Ribosomal protein L2, IPR008991:Translation protein SH3-like domain, IPR014722:Ribosomal protein L2 domain 2, IPR022666:Ribosomal Proteins L2, RNA binding domain, IPR022669:Ribosomal protein L2, C-terminal, IPR012340:Nucleic acid-binding, OB-fold" CG7636 11-Aug-17 DroID_v2017_08 "Drer\mrpl2, Drer\rpl8" "Scer\RPL2B, Scer\RPL2A, Scer\RML2" "Cele\mrpl-2, Cele\rpl-2" - "Mmus\Rpl8, Mmus\Mrpl2" "Hsap\MRPL2, Hsap\RPL8" "viable,visible" trichogen cell FBgn0065305 l(2)SH1971 lethal (2) SH1971 http://flybase.org/reports/FBgn0065305 gene - - - "l(2)SH1971, l(2)SH2 1971" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014936 anon-92Eb anon-92Eb http://flybase.org/reports/FBgn0014936 - gene - - - "sue, anon-92Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264870 CR44061 - http://flybase.org/reports/FBgn0264870 non_protein_coding_gene - - - CR44061 - CR44061 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011201 LysA Lysozyme A http://flybase.org/reports/FBgn0011201 - gene lysozyme activity ; GO:0003796 | inferred from sequence or structural similarity lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 - - LysA "IPR023346:Lysozyme-like domain, IPR001916:Glycoside hydrolase, family 22, IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR019799:Glycoside hydrolase, family 22, conserved site" - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage && larval stage FBgn0011174 l(1)291-44 lethal (1) 291-44 http://flybase.org/reports/FBgn0011174 FBgn0010199 gene - - - "291-44, l(1)291-44" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261582 CG42692 - http://flybase.org/reports/FBgn0261582 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42692 - CG42692 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033703 CG13170 - http://flybase.org/reports/FBgn0033703 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13170 - CG13170 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC06298 IE -1.582520474 -2.163717116 -0.840088367 -3.940983292 0.11281163 -1.008063469 FBgn0014886 Su(phl)43B Suppressor of pole hole 43B http://flybase.org/reports/FBgn0014886 - gene - - - "Su(D-raf)43B, Su(phl)43B" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031512 CG15404 - http://flybase.org/reports/FBgn0031512 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15404 - CG15404 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0083083 l(2)49Fn l(2)49Fn http://flybase.org/reports/FBgn0083083 gene - - - l(2)49Fn - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible" wing FBgn0001898 l(2)21Fd lethal (2) 21Fd http://flybase.org/reports/FBgn0001898 - gene - - - "l(2)neh-12, l(2)neh12, l(2)21Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069920 CG41131 - http://flybase.org/reports/FBgn0069920 protein_coding_gene - - - CG41131 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063127 pncr002:3R putative noncoding RNA 002:3R http://flybase.org/reports/FBgn0063127 non_protein_coding_gene - - - "pncr002:3R, CR33938, BcDNA:LP03188" - CR33938 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085639 CG41389 - http://flybase.org/reports/FBgn0085639 protein_coding_gene - - - CG41389 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027539 lili lilipod http://flybase.org/reports/FBgn0027539 FBgn0062072 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of BMP signaling pathway ; GO:0030513 | inferred from genetic interaction with tkv inferred from genetic interaction with Dad cellular_component ; GO:0005575 | no biological data available "BcDNA:GH12663, anon-WO0118547.355, CG5807, lili" "IPR006876:LMBR1-like membrane protein, IPR008075:Lipocalin-interacting membrane receptor" CG5807 11-Aug-17 DroID_v2017_08 "Drer\lmbr1, Drer\lmbr1l" - Cele\R05D3.2 "Xtro\lmbr1, Xtro\lmbr1l" "Mmus\Lmbr1, Mmus\Lmbr1l" "Hsap\LMBR1, Hsap\LMBR1L" "viable,fertile" "germline cell,male" FBgn0083249 E(smoDN)O Enhancer of smoDN group O http://flybase.org/reports/FBgn0083249 gene - smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "Group O, E(smoDN)O" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039488 CG6066 - http://flybase.org/reports/FBgn0039488 protein_coding_gene chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR009269 "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from electronic annotation with InterPro:IPR009269 Notch signaling pathway ; GO:0007219 | inferred from electronic annotation with InterPro:IPR009269 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG6066 IPR009269:NF-kappa-B-activating protein CG6066 11-Aug-17 DroID_v2017_08 Drer\nkap - Cele\let-504 Xtro\nkap "Mmus\Nkapl, Mmus\Nkap" "Hsap\NKAP, Hsap\NKAPL" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,female fertile,female sterile" "embryonic/larval neuroblast,ganglion mother cell" FBgn0267868 CR46156 - http://flybase.org/reports/FBgn0267868 non_protein_coding_gene - - - CR46156 - CR46156 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259603 B0519 - http://flybase.org/reports/FBgn0259603 gene - - - B0519 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0265840 CR44629 - http://flybase.org/reports/FBgn0265840 non_protein_coding_gene - - - CR44629 - CR44629 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024206 ol2 oocyte localisation 2 http://flybase.org/reports/FBgn0024206 - gene - - - ol2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069319 X-179-36 X-179-36 http://flybase.org/reports/FBgn0069319 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-179-36 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect" FBgn0036842 CG3797 - http://flybase.org/reports/FBgn0036842 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG3797 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG3797 11-Aug-17 DroID_v2017_08 "Drer\ugt2b3, Drer\ugt1b5, Drer\ugt2b6, Drer\zgc:172315, Drer\ugt5a1, Drer\ugt5a2, Drer\ugt2b5, Drer\ugt5e1, Drer\ugt1b7, Drer\ugt5d1, Drer\ugt5c3, Drer\ugt1b4, Drer\ugt1b3, Drer\ugt2a2, Drer\ugt1ab, Drer\ugt5b6, Drer\ugt8, Drer\ugt5a5, Drer\ugt5b3, Drer\ugt5c1, Drer\ugt2b1, Drer\ugt5b1, Drer\ugt5f1, Drer\ugt1b2, Drer\ugt5g1, Drer\ugt5g2, Drer\ugt2a5, Drer\ugt5b2, Drer\ugt2a6, Drer\ugt5c2, Drer\ugt5a4" Scer\ATG26 "Cele\ugt-44, Cele\ugt-60, Cele\C23G10.6, Cele\ugt-31, Cele\ugt-33, Cele\ugt-51, Cele\ugt-62, Cele\ugt-47, Cele\ugt-46, Cele\ugt-8, Cele\ugt-59, Cele\F10D2.8, Cele\ugt-49, Cele\ugt-21, Cele\ugt-43, Cele\ugt-30, Cele\ugt-22, Cele\H23N18.4, Cele\ugt-28, Cele\ugt-12, Cele\C55H1.1, Cele\ugt-18, Cele\ugt-26, Cele\ugt-58, Cele\ugt-6, Cele\ugt-40, Cele\ugt-35, Cele\ugt-53, Cele\C03A7.13, Cele\ugt-56, Cele\ugt-29, Cele\ugt-27, Cele\ugt-24, Cele\ugt-37, Cele\ugt-14, Cele\ugt-13, Cele\ugt-41, Cele\ugt-50, Cele\ugt-39, Cele\ugt-38, Cele\ugt-7, Cele\ugt-9, Cele\ugt-15, Cele\ugt-23, Cele\ugt-10, Cele\ugt-55, Cele\ugt-34, Cele\ugt-16, Cele\ugt-48, Cele\C03A7.12, Cele\ugt-17, Cele\ugt-45, Cele\ugt-5, Cele\ugt-36, Cele\ugt-32, Cele\ugt-3, Cele\Y43D4A.2, Cele\ugt-1, Cele\ugt-4, Cele\ugt-25, Cele\ugt-42, Cele\ugt-2, Cele\ugt-54, Cele\ugt-52, Cele\ugt-61, Cele\ugt-11, Cele\ugt-19, Cele\ugt-20, Cele\K04A8.10" "Xtro\ugt2a1, Xtro\ugt3a2, Xtro\ugt2b4, Xtro\ugt8, Xtro\ugt1a6" "Mmus\Ugt1a2, Mmus\Ugt2b1, Mmus\Ugt1a9, Mmus\Ugt3a2, Mmus\Ugt2b38, Mmus\Ugt2b36, Mmus\Ugt3a1, Mmus\Ugt8a, Mmus\Ugt2a1, Mmus\Ugt1a6b, Mmus\Ugt2b5, Mmus\Ugt1a5, Mmus\Ugt1a7c, Mmus\Ugt2b37, Mmus\Ugt1a1, Mmus\Ugt2a3, Mmus\Ugt2b35, Mmus\Ugt2b34" "Hsap\UGT1A10, Hsap\UGT2B10, Hsap\UGT8, Hsap\UGT1A3, Hsap\UGT1A1, Hsap\UGT1A6, Hsap\UGT1A7, Hsap\UGT2A3, Hsap\UGT2B17, Hsap\UGT3A2, Hsap\UGT1A8, Hsap\UGT3A1, Hsap\UGT1A9, Hsap\UGT2B15, Hsap\UGT2A2, Hsap\UGT1A4, Hsap\UGT2B7, Hsap\UGT2B28, Hsap\UGT2B11, Hsap\UGT2B4, Hsap\UGT1A5" FBgn0034027 CG8187 - http://flybase.org/reports/FBgn0034027 protein_coding_gene - - - CG8187 IPR025164:Putative adhesin CG8187 11-Aug-17 DroID_v2017_08 Drer\fam185a - - Xtro\fam185a Mmus\Fam185a Hsap\FAM185A viable FBgn0015695 E(cact[E10])11 "Enhancer of cactus[E10], number 11" http://flybase.org/reports/FBgn0015695 - gene - - - E(cact[E10])11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044445 EP912 EP912 http://flybase.org/reports/FBgn0044445 gene - - - EP912 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0267679 CR46015 - http://flybase.org/reports/FBgn0267679 non_protein_coding_gene - - - CR46015 - CR46015 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051093 CG31093 - http://flybase.org/reports/FBgn0051093 protein_coding_gene - - - "CG4964, BcDNA:AT30660, CG31093" - CG31093 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013480 l(1)1PP18 lethal (1) 1PP18 http://flybase.org/reports/FBgn0013480 - gene - - - l(1)1PP18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,rescuable maternal effect" "dorsal closure embryo,germline clone" FBgn0266037 CR44802 - http://flybase.org/reports/FBgn0266037 non_protein_coding_gene - - - "CR44802, lincRNA.87" - CR44802 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058133 CG40133 - http://flybase.org/reports/FBgn0058133 protein_coding_gene - - - CG40133 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020815 l(3)L0839 lethal (3) L0839 http://flybase.org/reports/FBgn0020815 - gene - - - l(3)L0839 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260662 U5-116k - http://flybase.org/reports/FBgn0260662 protein_coding_gene - - - U5-116k - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263108 BtbVII BTB-protein-VII http://flybase.org/reports/FBgn0263108 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 "BtbVII, CG43365, BTB-VII, CG11494, BcDNA:GH07729, CG14956, BTBVII" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical, IPR000210:BTB/POZ domain, IPR007889:DNA binding HTH domain, Psq-type, IPR011333:SKP1/BTB/POZ domain, IPR009057:Homeobox domain-like" CG43365 11-Aug-17 DroID_v2017_08 - - "Cele\sdz-28, Cele\btb-13" - "Mmus\Nacc2, Mmus\Nacc1" "Hsap\ZBTB12, Hsap\ZBTB9" DRSC08151 E -0.397614564 -1.031585472 1.589887515 -0.743215106 0.34181364 -0.218373287 FBgn0020884 Thin-wing Thin-wing http://flybase.org/reports/FBgn0020884 - gene - - - "Tn, Thin-wing" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile" wing FBgn0039741 CG7943 - http://flybase.org/reports/FBgn0039741 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 CG7943 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG7943 11-Aug-17 DroID_v2017_08 "Drer\slc25a51b, Drer\slc25a51a" - Cele\T20D3.5 "Xtro\slc25a53, Xtro\slc25a51" "Mmus\Slc25a53, Mmus\Slc25a51" "Hsap\SLC25A52, Hsap\SLC25A53, Hsap\SLC25A51" viable FBgn0028184 l(3)S024120 lethal (3) S024120 http://flybase.org/reports/FBgn0028184 gene - - - "0241/20, l(3)S024120" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264515 CR43914 - http://flybase.org/reports/FBgn0264515 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43914, CR43914, lincRNA.536" - CR43914 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082334 HM786 HM786 http://flybase.org/reports/FBgn0082334 gene - - - HM786 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030544 CG13403 - http://flybase.org/reports/FBgn0030544 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG13403 - CG13403 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" DRSC19535 K 0.639832224 0.172376131 0.436685363 0.403573265 0.5687291 1.552636706 FBgn0001507 l(1)10Fa lethal (1) 10Fa http://flybase.org/reports/FBgn0001507 FBgn0001618 gene - - - "6, l(1)L6, l(1)10Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266903 CR45363 - http://flybase.org/reports/FBgn0266903 non_protein_coding_gene - - - CR45363 - CR45363 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033989 CG7639 - http://flybase.org/reports/FBgn0033989 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available outer membrane ; GO:0019867 | inferred from electronic annotation with InterPro:IPR000184 CG7639 "IPR000184:Bacterial surface antigen (D15), IPR034746:POTRA domain" CG7639 11-Aug-17 DroID_v2017_08 "Drer\samm50l, Drer\samm50" Scer\SAM50 Cele\gop-3 Xtro\samm50 Mmus\Samm50 Hsap\SAMM50 "viable,visible" trichogen cell FBgn0067663 poached poached http://flybase.org/reports/FBgn0067663 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available poached - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,germline clone" "egg chamber,germline clone" FBgn0040672 CG12476 - http://flybase.org/reports/FBgn0040672 protein_coding_gene - - - CG12476 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065674 l(2)SH0677 lethal (2) SH0677 http://flybase.org/reports/FBgn0065674 gene - - - "l(2)SH0677, l(2)SH2 0677" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011361 ND-ACP NADH dehydrogenase (ubiquinone) acyl carrier protein http://flybase.org/reports/FBgn0011361 FBgn0017568 protein_coding_gene ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process ; GO:0000036 | inferred from biological aspect of ancestor with PANTHER:PTN000466551 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process ; GO:0000036 | inferred from sequence alignment with UniProtKB:P52505 acyl binding ; GO:0000035 | inferred from biological aspect of ancestor with PANTHER:PTN000466551 phosphopantetheine binding ; GO:0031177 | inferred from sequence alignment with UniProtKB:P52505 phosphopantetheine binding ; GO:0031177 | inferred from biological aspect of ancestor with PANTHER:PTN000466551 "fatty acid biosynthetic process ; GO:0006633 | inferred from electronic annotation with InterPro:IPR003231 lipid A biosynthetic process ; GO:0009245 | inferred from biological aspect of ancestor with PANTHER:PTN000466551 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence alignment with UniProtKB:P52505 fatty acid biosynthetic process ; GO:0006633 | inferred from sequence alignment with UniProtKB:P52505 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000466551 mitochondrion ; GO:0005739 | inferred from sequence alignment with UniProtKB:P52505 "mtACP, ND-AcC, l(3)j4A6, CG9160, mtacp1, mtACP1, l(3)1303, ACPM, ND-ACP, MTACP1A, mtACP1A, MTACP1B, mtACP1B" "IPR009081:Phosphopantetheine binding ACP domain, IPR003231:Acyl carrier protein (ACP)" CG9160 11-Aug-17 DroID_v2017_08 "Drer\ndufab1a, Drer\ndufab1b, Drer\si:dkey-23n7.10, Drer\spsb3a" Scer\ACP1 "Cele\F37C12.3, Cele\F16B4.6, Cele\Y56A3A.19" "Xtro\ndufab1, Xtro\spsb3" "Mmus\Spsb3, Mmus\Ndufab1" "Hsap\SPSB3, Hsap\NDUFAB1" " embryonic stage | stage >=14 , embryonic stage | stage >=15 , embryonic stage -- adult stage , adult stage && oogenesis stage | stage S10-11 " " embryonic/larval tracheal system

, embryonic/larval lateral trunk

, embryonic/larval dorsal trunk

, nurse cell

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,visible,partially lethal - majority die,some die during pupal stage,viable" "spermatid,onion stage spermatid,germarium,trachea,trichogen cell,mesothoracic tergum" FBgn0263899 l(3)OL61 - http://flybase.org/reports/FBgn0263899 gene - - - l(3)OL61 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0000789 fs(1)C5 female sterile (1) C5 http://flybase.org/reports/FBgn0000789 - gene - - - fs(1)C5 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "chorion,ovary" FBgn0263470 snoRNA:Tudor-SN-a - http://flybase.org/reports/FBgn0263470 snoRNA_gene - - - "snoRNA:Tudor-SN-a, snoRNA:tudor-SN-a" - CR43585 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053223 CG33223 - http://flybase.org/reports/FBgn0053223 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of MyD88-dependent toll-like receptor signaling pathway ; GO:0034126 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG33223 "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG33223 11-Aug-17 DroID_v2017_08 Drer\ubb - - - Mmus\Rps27a Hsap\UBB FBgn0038334 h-cup heineken-cup http://flybase.org/reports/FBgn0038334 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.172, h-cup, CG6130" IPR008555:Suppressor of IKBKE 1 CG6130 11-Aug-17 DroID_v2017_08 "Drer\sike1, Drer\fgfr1op2" - Cele\C14B1.8 "Xtro\sike1, Xtro\fgfr1op2" "Mmus\Sike1, Mmus\Fgfr1op2" "Hsap\FGFR1OP2, Hsap\SIKE1" viable FBgn0043383 EP596 EP596 http://flybase.org/reports/FBgn0043383 gene - - - "EP0596, EP596" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "dorsocentral bristle,scutellar bristle,trichogen cell" FBgn0262948 CG43267 - http://flybase.org/reports/FBgn0262948 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43267 - CG43267 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051159 mRRF2 mitochondrial ribosome recycling factor 2 http://flybase.org/reports/FBgn0051159 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with UniProtKB:Q969S9" ribosome disassembly ; GO:0032790 | inferred from sequence or structural similarity with UniProtKB:Q969S9 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:Q969S9 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000003638 "CG6943, CG31159, dEF-G2, mRRF2, EF-G2" "IPR000640:Translation elongation factor EFG, V domain, IPR000795:Transcription factor, GTP-binding domain, IPR005225:Small GTP-binding protein domain, IPR009000:Translation protein, beta-barrel domain, IPR009022:Elongation factor G, III-V domain, IPR030851:Ribosome-releasing factor 2, mitochondrial, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031157:Tr-type G domain, conserved site" CG31159 11-Aug-17 DroID_v2017_08 "Drer\gfm1, Drer\gfm2" "Scer\MEF2, Scer\MEF1" "Cele\gfm-1, Cele\Y119D3B.14" Xtro\gfm2 "Mmus\Gfm1, Mmus\Gfm2" "Hsap\GFM2, Hsap\GFM1" FBgn0267619 CR45957 - http://flybase.org/reports/FBgn0267619 non_protein_coding_gene - - - CR45957 - CR45957 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002625 M(3)99B Minute (3) 99B http://flybase.org/reports/FBgn0002625 - gene - - - "M(3)1, M(3)l, M, M(3)99B" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible,developmental rate defective" macrochaeta FBgn0046321 roX1-CES roX1 chromatin entry site http://flybase.org/reports/FBgn0046321 region - - - "roX1-CES, roX1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014323 l(3)ry151 lethal (3) ry151 http://flybase.org/reports/FBgn0014323 - gene - - - l(3)ry151 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050472 CG30472 - http://flybase.org/reports/FBgn0050472 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30472 - CG30472 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0050047 CG30047 - http://flybase.org/reports/FBgn0050047 protein_coding_gene - - cellular_component ; GO:0005575 | no biological data available CG30047 IPR007484:Peptidase M28 CG30047 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\YDR415C, Scer\APE3, Scer\PFF1, Scer\VPS70" "Cele\B0495.7, Cele\C44B7.11" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0027620 Acf ATP-dependent chromatin assembly factor large subunit http://flybase.org/reports/FBgn0027620 FBgn0021749 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 protein binding ; GO:0005515 | inferred from physical interaction with Iswi DNA binding ; GO:0003677 | inferred from direct assay nucleosome-dependent ATPase activity ; GO:0070615 | contributes_to inferred by curator from GO:0008623 nucleosome-dependent ATPase activity ; GO:0070615 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement histone acetyltransferase activity ; GO:0004402 | NOT inferred from direct assay "neuron development ; GO:0048666 | inferred from mutant phenotype regulation of heterochromatin assembly ; GO:0031445 | inferred from mutant phenotype nucleosome assembly ; GO:0006334 | inferred from direct assay muscle organ development ; GO:0007517 | inferred from mutant phenotype regulation of ATPase activity ; GO:0043462 | inferred from direct assay nucleosome mobilization ; GO:0042766 | traceable author statement chromatin assembly ; GO:0031497 | inferred from direct assay chromatin assembly or disassembly ; GO:0006333 | traceable author statement nucleosome positioning ; GO:0016584 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype nucleosome mobilization ; GO:0042766 | inferred from direct assay epidermis development ; GO:0008544 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay" ACF complex ; GO:0016590 | inferred from direct assay inferred from physical interaction with Iswi CHRAC ; GO:0008623 | inferred from direct assay NURF complex ; GO:0016589 | NOT inferred from direct assay ACF complex ; GO:0016590 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "ACF1, ACF/CHRAC, ACF, Acf-1, CHRAC, dACF, dCHRAC, p170/p185, acf1, CAF, CHRAC-175, CG1966, Acf1, p175, p170, 175K protein, Acf" "IPR001487:Bromodomain, IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR013136:WSTF/Acf1/Cbp146, IPR018501:DDT domain, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR028941:WHIM2 domain" CG1966 11-Aug-17 DroID_v2017_08 "Drer\baz1a, Drer\baz2a, Drer\baz2ba, Drer\LOC100536981" "Scer\GCN5, Scer\YPL216W" Cele\athp-2 "Xtro\baz1a, Xtro\baz1b, Xtro\baz2b, Xtro\baz2a" "Mmus\Baz2b, Mmus\Baz2a, Mmus\Baz1b, Mmus\Baz1a" "Hsap\BAZ2A, Hsap\BAZ1A, Hsap\BAZ2B, Hsap\BAZ1B" embryonic stage -- adult stage "viable,fertile,visible,mitotic cell cycle defective,cell death defective,lethal,partially lethal - majority die,recessive,developmental rate defective,suppressor of variegation,non-suppressor of variegation" "eye,ommatidium,antenna,ectopic,supernumerary,photoreceptor cell | third instar larval stage,eye disc | third instar larval stage,morphogenetic furrow,nucleus | third instar larval stage2314,embryonic/larval salivary gland | third instar larval stage,S phase,nucleus | blastoderm stage" FBgn0065761 l(2)SH0478 lethal (2) SH0478 http://flybase.org/reports/FBgn0065761 gene - - - "l(2)SH0478, l(2)SH2 0478" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062571 Mod(var)E1377 Mod(var)E1377 http://flybase.org/reports/FBgn0062571 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1377, Mod(var)E1377" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,enhancer of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0026662 l(1)G0178 lethal (1) G0178 http://flybase.org/reports/FBgn0026662 - gene - - - l(1)G0178 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037590 Or85b Odorant receptor 85b http://flybase.org/reports/FBgn0037590 protein_coding_gene odorant binding ; GO:0005549 | inferred from physical interaction with Orco odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "85b, DOR115, 85A.1, CG11735, Or85b, DmOR85b" "IPR004117:Olfactory receptor, insect" CG11735 11-Aug-17 DroID_v2017_08 - - Cele\T11F8.1 - - - viable FBgn0061156 l(2)30Ba lethal (2) 30Ba http://flybase.org/reports/FBgn0061156 gene - - - "K2, l(2)30Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0063376 snoRNA:U76:54Eb snoRNA:U76:54Eb http://flybase.org/reports/FBgn0063376 snoRNA_gene - - - "U76snoRNA, CR32891, snoRNA:U76:54Eb" - CR32891 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035298 SCOT Succinyl-CoA:3-ketoacid CoA transferase http://flybase.org/reports/FBgn0035298 protein_coding_gene 3-oxoacid CoA-transferase activity ; GO:0008260 | inferred from sequence or structural similarity with UniProtKB:P55809 3-oxoacid CoA-transferase activity ; GO:0008260 | inferred from direct assay 3-oxoacid CoA-transferase activity ; GO:0008260 | inferred from sequence or structural similarity with UniProtKB:Q29551 ketone body catabolic process ; GO:0046952 | inferred from sequence or structural similarity with UniProtKB:P55809 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P55809 "CT1116, cDNA B, BcDNA:RH54340, SCOT, CG1140, DmSCOT" "IPR004163:Coenzyme A transferase binding site, IPR004164:Coenzyme A transferase active site, IPR004165:Coenzyme A transferase family I, IPR012791:3-oxoacid CoA-transferase, subunit B, IPR012792:3-oxoacid CoA-transferase, subunit A, IPR014388:3-oxoacid CoA-transferase" CG1140 11-Aug-17 DroID_v2017_08 "Drer\gipc2, Drer\oxct1b, Drer\gipc1, Drer\gipc3, Drer\oxct1a" - "Cele\gipc-1, Cele\C05C10.3, Cele\gipc-2" "Xtro\oxct1, Xtro\gipc2, Xtro\gipc1, Xtro\gipc3" "Mmus\Gipc1, Mmus\Oxct2b, Mmus\Oxct2a, Mmus\Gipc3, Mmus\Oxct1, Mmus\Gipc2" "Hsap\OXCT2, Hsap\OXCT1, Hsap\GIPC1, Hsap\GIPC3, Hsap\GIPC2" "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0032485 CG9426 - http://flybase.org/reports/FBgn0032485 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 actin binding ; GO:0003779 | inferred from sequence or structural similarity protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN001229449 regulation of cell cycle ; GO:0051726 | inferred from direct assay Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from biological aspect of ancestor with PANTHER:PTN001973695 "CG9426, Ipp" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR017096:BTB-kelch protein, IPR015916:Galactose oxidase, beta-propeller, IPR015915:Kelch-type beta propeller" CG9426 11-Aug-17 DroID_v2017_08 "Drer\klhl31, Drer\klhl29, Drer\ipp, Drer\kbtbd8, Drer\klhl2, Drer\klhl3, Drer\klhl43, Drer\LOC100334314" - Cele\kel-8 "Xtro\ipp, Xtro\kbtbd3" "Mmus\Ccin, Mmus\Klhl31, Mmus\Kbtbd8, Mmus\Klhl29, Mmus\Klhl2, Mmus\Klhl3, Mmus\Ipp" "Hsap\KLHL3, Hsap\CCIN, Hsap\KLHL31, Hsap\KLHL29, Hsap\KBTBD8, Hsap\KLHL2, Hsap\IPP" "viable,fertile" FBgn0025712 CG13920 - http://flybase.org/reports/FBgn0025712 FBgn0035250 protein_coding_gene - - - "CK00246, BEST:CK00246, CG13920" "IPR032808:DoxX family, IPR029693:Transmembrane protein 35A" CG13920 11-Aug-17 DroID_v2017_08 Drer\tmem35 - - "Xtro\zmym6nb, Xtro\tmem35" Mmus\Tmem35a Hsap\TMEM35A "lethal,viable" FBgn0085645 CG41425 - http://flybase.org/reports/FBgn0085645 protein_coding_gene - - - CG41425 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036874 brv1 brivido-1 http://flybase.org/reports/FBgn0036874 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR003915 calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity detection of temperature stimulus involved in thermoception ; GO:0050960 | inferred from mutant phenotype cellular response to cold ; GO:0070417 | inferred from mutant phenotype detection of mechanical stimulus ; GO:0050982 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 "CT26822, CG9472, brv1" "IPR003915:Polycystic kidney disease type 2 protein, IPR013122:Polycystin cation channel, PKD1/PKD2" CG9472 11-Aug-17 DroID_v2017_08 "Drer\pkd1l3, Drer\pkd2, Drer\loxhd1a, Drer\pkd1b, Drer\pkd1a, Drer\LOC100537993, Drer\pkd2l1" - "Cele\pkd-2, Cele\lov-1" "Xtro\pkd2, Xtro\pkd1" "Mmus\Pkd1, Mmus\Pkd1l1, Mmus\Pkdrej, Mmus\Pkd2, Mmus\Pkd1l3, Mmus\Pkd2l1, Mmus\Pkd1l2, Mmus\Pkd2l2" "Hsap\PKD2L1, Hsap\PKDREJ, Hsap\PKD1L1, Hsap\PKD2L2, Hsap\PKD1, Hsap\PKD2, Hsap\PKD1L3" "viable,cold stress response defective,recessive" FBgn0266701 CR45191 - http://flybase.org/reports/FBgn0266701 non_protein_coding_gene - - - CR45191 - CR45191 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262352 CG43050 - http://flybase.org/reports/FBgn0262352 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43050, DMG8-chr2L.24.001, lincRNA.126, TCONS_00035985" IPR012674:Calycin CG43050 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264722 CR43990 - http://flybase.org/reports/FBgn0264722 non_protein_coding_gene - - - "CR43990, lincRNA.490" - CR43990 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260502 Pak::Pkn - http://flybase.org/reports/FBgn0260502 engineered_fusion_gene - - - "Pak::Pkn, Pak-Pkn" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036173 CG7394 - http://flybase.org/reports/FBgn0036173 protein_coding_gene ATPase activator activity ; GO:0001671 | inferred from sequence or structural similarity with UniProtKB:Q07914 neurogenesis ; GO:0022008 | inferred from mutant phenotype protein import into mitochondrial matrix ; GO:0030150 | inferred from sequence or structural similarity with UniProtKB:Q07914 presequence translocase-associated import motor ; GO:0001405 | inferred from sequence or structural similarity with UniProtKB:Q07914 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q07914 "D.M.UKP, BcDNA:RE52392, CG7394, TIM14" IPR001623:DnaJ domain CG7394 11-Aug-17 DroID_v2017_08 "Drer\dnajc19, Drer\dnajc15" "Scer\PAM18, Scer\MDJ2" Cele\dnj-21 "Xtro\dnajc15, Xtro\dnajc19" "Mmus\Dnajc19, Mmus\Dnajc15, Mmus\Dnajc19-ps" "Hsap\DNAJC19, Hsap\DNAJC15" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0086855 CG17078 - http://flybase.org/reports/FBgn0086855 protein_coding_gene - - - "CG17078, anon-21Cb" - CG17078 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-182e10.4, Drer\zgc:113210, Drer\si:ch211-166e11.5, Drer\LOC101886754, Drer\LOC108179115, Drer\LOC101884898, Drer\si:dkey-15h8.10" - - - - - "viable,body color defective" mesothoracic tergum FBgn0011131 l(1)Q205 lethal (1) Q205 http://flybase.org/reports/FBgn0011131 FBgn0010210 gene - - - l(1)Q205 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0025137 su(RpII140[Z36])S10 su(RpII140[Z36])S10 http://flybase.org/reports/FBgn0025137 - gene - - - "Z36[S10], su(RpII140[Z36])S10" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250736 l(3)S002237 lethal (3) S002237 http://flybase.org/reports/FBgn0250736 gene - - - "l(3)S002237, l(3)s002237" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060445 l(3)S122413a lethal (3) S122413a http://flybase.org/reports/FBgn0060445 gene - - - "1224/13, l(3)S122413a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058456 18SrRNA:CR40456 18SrRNA:CR40456 http://flybase.org/reports/FBgn0058456 rRNA_gene - - - "CR40456, 18SrRNA:CR40456" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266983 CR45434 - http://flybase.org/reports/FBgn0266983 non_protein_coding_gene - - - CR45434 - CR45434 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031310 Vps29 Vacuolar protein sorting 29 http://flybase.org/reports/FBgn0031310 protein_coding_gene protein transporter activity ; GO:0008565 | contributes_to inferred from sequence or structural similarity with SGD:S000001054 "retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with SGD:S000001054" "late endosome membrane ; GO:0031902 | inferred from direct assay retromer, cargo-selective complex ; GO:0030906 | inferred from sequence or structural similarity with SGD:S000001054 endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000001054" "CG4764, DmVps29, Vps29, VPS29" "IPR000979:Phosphodiesterase MJ0936/Vps29, IPR024654:Calcineurin-like phosphoesterase domain, lpxH type, IPR028661:Vacuolar protein sorting-associated protein 29, IPR029052:Metallo-dependent phosphatase-like" CG4764 11-Aug-17 DroID_v2017_08 Drer\vps29 Scer\VPS29 Cele\vps-29 Xtro\vps29 Mmus\Vps29 Hsap\VPS29 "viable,fertile" FBgn0046335 en::Xlae\Meis3 Meis3 http://flybase.org/reports/FBgn0046335 engineered_fusion_gene - - - en::Xlae\Meis3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,visible" "eye,ectopic,antenna,leg,distal,third segment of antenna,analia,genital disc" FBgn0065954 l(2)SH0065 lethal (2) SH0065 http://flybase.org/reports/FBgn0065954 gene - - - "l(2)SH0065, l(2)SH2 0065" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050031 CG30031 - http://flybase.org/reports/FBgn0050031 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model proteolysis ; GO:0006508 | inferred from sequence model - "CG30031, endo-I" - CG30031 11-Aug-17 DroID_v2017_08 "Drer\prss60.1, Drer\zgc:112160, Drer\ctrl, Drer\try, Drer\prss60.2, Drer\si:dkeyp-93a5.2, Drer\prss60.3, Drer\zgc:163079, Drer\si:ch211-165b19.9, Drer\zgc:92590, Drer\zgc:153968, Drer\zgc:112038, Drer\zgc:123295, Drer\tmprss4b, Drer\LOC562139, Drer\zgc:55888" - "Cele\try-1, Cele\rab-11.1" - "Mmus\Prss3, Mmus\2210010C04Rik, Mmus\Prss34, Mmus\Prss53, Mmus\Prss36, Mmus\Try10, Mmus\Prss55, Mmus\Gm5771, Mmus\Try4, Mmus\Gm10334, Mmus\Prss2, Mmus\Prss1" "Hsap\PRSS1, Hsap\PRSS3, Hsap\CMA1, Hsap\PRSS45, Hsap\PRSS27, Hsap\TPSG1, Hsap\PRSS33, Hsap\PRSS8, Hsap\PRSS36, Hsap\PRSS53, Hsap\PRSS22, Hsap\PRSS38" FBgn0033627 CG13204 - http://flybase.org/reports/FBgn0033627 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 basal RNA polymerase II transcription machinery binding ; GO:0001099 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 "CG13204, 13204" "IPR004210:BESS motif, IPR006578:MADF domain" CG13204 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-207i20.3, Drer\zgc:152938, Drer\si:ch73-59f11.3, Drer\LOC100330838" - "Cele\madf-3, Cele\madf-9" - - - "viable,fertile" FBgn0023123 anon-10Ak anon-10Ak http://flybase.org/reports/FBgn0023123 - gene - - - "3, anon-10Ak" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266529 T:SS-BiP Signal sequence of Hsc70-3 http://flybase.org/reports/FBgn0266529 engineered_tag - - - T:SS-BiP - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265082 Cdep Chondrocyte-derived ezrin-like domain containing protein http://flybase.org/reports/FBgn0265082 protein_coding_gene "cytoskeletal protein binding ; GO:0008092 | inferred from electronic annotation with InterPro:IPR000798 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057, InterPro:IPR025898 Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with HGNC:16460 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity" regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 Rac protein signal transduction ; GO:0016601 | inferred from sequence or structural similarity with HGNC:16460 extrinsic component of membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000798 cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 cellular_component ; GO:0005575 | no biological data available "CG34306, CG44193, Cdep, CG2008, i23, CG1283, CDEP, CG31536, BcDNA:RH50880, BcDNA:AT26639" "IPR029071:Ubiquitin-related domain, IPR000299:FERM domain, IPR000798:Ezrin/radixin/moesin-like, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR014847:FERM adjacent (FA), IPR018979:FERM, N-terminal, IPR018980:FERM, C-terminal PH-like domain, IPR019747:FERM conserved site, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR025898:Tc3 transposase, DNA binding domain" CG44193 11-Aug-17 DroID_v2017_08 "Drer\farp2, Drer\farp1, Drer\frmd7, Drer\kmt2a, Drer\LOC557811" - "Cele\F52D10.6, Cele\frm-3" Xtro\frmd7 "Mmus\Farp2, Mmus\Frmd7, Mmus\Farp1" "Hsap\FRMD7, Hsap\FGD5, Hsap\FARP2, Hsap\FARP1" FBgn0263117 CG34377 - http://flybase.org/reports/FBgn0263117 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13858, CG34377, CG13859, CG13860, CG13861" "IPR013761:Sterile alpha motif/pointed domain, IPR001660:Sterile alpha motif domain" CG34377 11-Aug-17 DroID_v2017_08 "Drer\sash1a, Drer\sash3, Drer\samsn1a, Drer\sash1b, Drer\inppl1a, Drer\samsn1b" - - "Xtro\sash3, Xtro\samsn1, Xtro\sash1" "Mmus\Sash1, Mmus\Sash3, Mmus\Caskin2, Mmus\Inppl1, Mmus\Samsn1, Mmus\Samd5" "Hsap\SAMSN1, Hsap\SASH1, Hsap\SAMD5, Hsap\CASKIN2, Hsap\SASH3, Hsap\INPPL1" FBgn0017623 Eig76Eb Eig76Eb http://flybase.org/reports/FBgn0017623 - gene - - - "Eig76-2, Eig76Eb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025474 qkr58C quaking related 58C http://flybase.org/reports/FBgn0025474 - gene - - - "qrk58C, qkr58C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259971 CG42481 - http://flybase.org/reports/FBgn0259971 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42481 - CG42481 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028160 l(3)S041303 lethal (3) S041303 http://flybase.org/reports/FBgn0028160 gene - - - "l(3)041303, 0413/03, l(3)S041303" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0261633 CG42716 - http://flybase.org/reports/FBgn0261633 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG42716 IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42716 11-Aug-17 DroID_v2017_08 "Drer\pi15b, Drer\wu:fb59d01, Drer\glipr1b, Drer\glipr2l, Drer\crispld1b, Drer\crispld2, Drer\crispld1a, Drer\LOC100536500, Drer\pi15a, Drer\r3hdml, Drer\glipr2" "Scer\PRY2, Scer\PRY1, Scer\PRY3" - "Xtro\glipr2, Xtro\MGC108118, Xtro\crispld2, Xtro\crisp2, Xtro\crisp1, Xtro\crisp3, Xtro\r3hdml" "Mmus\Crisp4, Mmus\R3hdml, Mmus\Crisp2, Mmus\Pi15, Mmus\Clec18a, Mmus\Glipr2, Mmus\Glipr1l2, Mmus\Crispld2, Mmus\Crispld1, Mmus\Glipr1l1, Mmus\Crisp3, Mmus\Glipr1, Mmus\Crisp1, Mmus\Pi16" "Hsap\R3HDML, Hsap\CRISPLD1, Hsap\CLEC18B, Hsap\CRISP2, Hsap\CRISP1, Hsap\PI16, Hsap\CRISPLD2, Hsap\CLEC18C, Hsap\GLIPR1, Hsap\GLIPR1L1, Hsap\PI15, Hsap\GLIPR2, Hsap\CLEC18A, Hsap\GLIPR1L2" FBgn0027537 Nup93-1 Nucleoporin 93kD-1 http://flybase.org/reports/FBgn0027537 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Nup154 structural constituent of nuclear pore ; GO:0017056 | inferred from sequence or structural similarity with SGD:S000001898 SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype regulation of nucleus size ; GO:0097298 | inferred from mutant phenotype chromosome attachment to the nuclear envelope ; GO:0097240 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype protein targeting to nuclear inner membrane ; GO:0036228 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | NOT inferred from mutant phenotype nuclear pore organization ; GO:0006999 | inferred from sequence or structural similarity with SGD:S000001898 cellular protein localization ; GO:0034613 | inferred from mutant phenotype nuclear pore nuclear basket ; GO:0044615 | inferred from sequence or structural similarity with SGD:S000001898 "BcDNA:LD21129, Nup93-1, nup93, CG11092, Nup93" IPR007231:Nucleoporin interacting component Nup93/Nic96 CG11092 11-Aug-17 DroID_v2017_08 Drer\nup93 Scer\NIC96 Cele\npp-13 Xtro\nup93 Mmus\Nup93 Hsap\NUP93 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266898 CR45358 - http://flybase.org/reports/FBgn0266898 non_protein_coding_gene - - - CR45358 - CR45358 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005273 l(3)SG93 lethal (3) SG93 http://flybase.org/reports/FBgn0005273 - gene - - - "l(3)V-13, l(3)SG93" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0016921 nompD no mechanoreceptor potential D http://flybase.org/reports/FBgn0016921 - gene - - - "nomp, nompD" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005125 l(1)J413 lethal (1) J413 http://flybase.org/reports/FBgn0005125 - gene - - - l(1)J413 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" testis FBgn0010724 l(3)00643 lethal (3) 00643 http://flybase.org/reports/FBgn0010724 FBgn0011030 gene - - - "l(3)s2541, l(3)00643" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002258 l(3)68Fc lethal (3) 68Fc http://flybase.org/reports/FBgn0002258 - gene - - - "rsg20, l(3)rsg20, l(3)68Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039315 CG13658 - http://flybase.org/reports/FBgn0039315 protein_coding_gene - - - CG13658 "IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227" CG13658 11-Aug-17 DroID_v2017_08 - - "Cele\nhr-246, Cele\H06H21.8, Cele\C29F7.2, Cele\dhs-27, Cele\D1044.1, Cele\C29F7.1" - - - FBgn0086694 Bre1 Bre1 http://flybase.org/reports/FBgn0086694 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ligase activity ; GO:0016874 | inferred from mutant phenotype ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000002232 histone modification ; GO:0016570 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype histone ubiquitination ; GO:0016574 | inferred from sequence or structural similarity with SGD:S000002232 protein monoubiquitination ; GO:0006513 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern histone ubiquitination ; GO:0016574 | inferred from mutant phenotype nuclear chromatin ; GO:0000790 | colocalizes_with inferred from sequence or structural similarity with SGD:S000002232 nucleus ; GO:0005634 | inferred from direct assay "CG10542, bre1, l(3)01640, Bre1, dBre1, dBRE1, EC3-8, BRE1, Bre-1, bre-1" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR018957:Zinc finger, C3HC4 RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10542 11-Aug-17 DroID_v2017_08 "Drer\pex10, Drer\rnf4, Drer\rnf20, Drer\rnf40, Drer\si:ch211-247l8.8, Drer\rnf185" "Scer\BRE1, Scer\PEX10" "Cele\rfp-1, Cele\Y47G6A.31, Cele\rnf-5" "Xtro\rnf20, Xtro\rnf40, Xtro\rnf5" "Mmus\Rnf185, Mmus\Rnf4, Mmus\Rnf20, Mmus\Rnf5, Mmus\Trim39, Mmus\Rnf40, Mmus\Pex10" "Hsap\RNF20, Hsap\PEX10, Hsap\TRIM39, Hsap\RNF5, Hsap\RNF185, Hsap\RNF4, Hsap\RNF40" DRSC09742 IK -2.360815611 0.459077283 0.304333201 0.280659031 2.424965315 -0.290980604 FBgn0264831 CR44039 - http://flybase.org/reports/FBgn0264831 non_protein_coding_gene - - - CR44039 - CR44039 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263587 CR43612 - http://flybase.org/reports/FBgn0263587 non_protein_coding_gene - - - CR43612 - CR43612 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052428 CG32428 - http://flybase.org/reports/FBgn0052428 protein_coding_gene - - - "CG5145, CG13249, CG32428" - CG32428 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal" DRSC11697 IEK -1.964313201 -2.097166378 -1.186976646 -1.563281552 2.220659533 0.676294215 FBgn0067858 T:TM-sev Transmembrane and extracellular domain of sev http://flybase.org/reports/FBgn0067858 engineered_tag - - - "T:TM-sev, T:sev" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044055 HB\T HB element transposase http://flybase.org/reports/FBgn0044055 transposable_element_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002492 "transposition, DNA-mediated ; GO:0006313 | inferred from electronic annotation with InterPro:IPR002492 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR002492" - HB\T "IPR002492:Transposase, Tc1-like" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026608 Act42A::Act88F Act42A::Act88F http://flybase.org/reports/FBgn0026608 - engineered_fusion_gene - - - Act42A::Act88F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001835 l(1)ts612 lethal (1) ts612 http://flybase.org/reports/FBgn0001835 - gene - - - l(1)ts612 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0266000 CG44774 - http://flybase.org/reports/FBgn0266000 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of cell migration ; GO:0030336 | inferred from biological aspect of ancestor with PANTHER:PTN001002650 negative regulation of cell migration ; GO:0030336 | inferred from sequence or structural similarity with HGNC:30702 Sin3 complex ; GO:0016580 | inferred from sequence or structural similarity with HGNC:30702 Sin3 complex ; GO:0016580 | inferred from biological aspect of ancestor with PANTHER:PTN001002650 "CG44774, CG4068, CR43698, CR43699" IPR026065:FAM60A CG44774 11-Aug-17 DroID_v2017_08 "Drer\fam60al, Drer\fam60a" - - - Mmus\Fam60a Hsap\FAM60A FBgn0262682 CR43152 - http://flybase.org/reports/FBgn0262682 non_protein_coding_gene - - - "CG43152, CR43152" - CR43152 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003322 sbs stubs http://flybase.org/reports/FBgn0003322 - gene - - - sbs - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male fertile,female sterile,visible" "wing,wing vein L2,wing vein L3,eye" FBgn0003639 Su(w[ch]) Suppressor of white-cherry http://flybase.org/reports/FBgn0003639 - gene - - - "Su(w[ch2]), Su(w[ch])" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263345 CR43426 - http://flybase.org/reports/FBgn0263345 non_protein_coding_gene - - - CR43426 - CR43426 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032368 spag4 sperm-associated antigen 4 http://flybase.org/reports/FBgn0032368 protein_coding_gene - nuclear envelope organization ; GO:0006998 | inferred from biological aspect of ancestor with PANTHER:PTN000308195 double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype nuclear envelope ; GO:0005635 | inferred from biological aspect of ancestor with PANTHER:PTN000308195 spindle microtubule ; GO:0005876 | colocalizes_with inferred from direct assay "CG6589, dspag, spag4, giac, Dspag4, Spag4" "IPR012919:SUN domain, IPR008979:Galactose-binding domain-like" CG6589 11-Aug-17 DroID_v2017_08 "Drer\zgc:152977, Drer\si:dkey-92f12.2, Drer\sun1" Scer\MPS3 "Cele\sun-1, Cele\unc-84" "Xtro\sun1, Xtro\LOC100127596" "Mmus\Sun3, Mmus\Sun5, Mmus\Sun1, Mmus\Spag4, Mmus\Sun2" "Hsap\SUN2, Hsap\SPAG4, Hsap\SUN1, Hsap\SUN3, Hsap\SUN5" "viable,male sterile,recessive,female fertile" "pre-elongation spermatid,elongation stage spermatid,spermatozoon,major mitochondrial derivative,minor mitochondrial derivative,individualization stage spermatid,cystic bulge,investment cone,waste bag" FBgn0040384 CG32795 - http://flybase.org/reports/FBgn0040384 protein_coding_gene - defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012926 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000484625 "CG2766, EG:BACN33B1.2, CG2716, CG32795" IPR012926:TMPIT-like CG32795 11-Aug-17 DroID_v2017_08 "Drer\tmem120b, Drer\zgc:103681, Drer\tmem120a" - Cele\M01G5.3 "Xtro\tmem120a, Xtro\tmem120b" "Mmus\Tmem120b, Mmus\Tmem120a" "Hsap\TMEM120B, Hsap\TMEM120A" "viable,fertile,visible" pigment cell FBgn0000967 fs(2)eo7 female sterile (2) eo7 http://flybase.org/reports/FBgn0000967 - gene molecular_function ; GO:0003674 | no biological data available female gonad development ; GO:0008585 | inferred from mutant phenotype male gonad development ; GO:0008584 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "fs(2)eoPP22, fs(2)eo-E, fs(2)eo7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male sterile" FBgn0070025 BG00459 BG00459 http://flybase.org/reports/FBgn0070025 gene - - - BG00459 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0052450 CG32450 - http://flybase.org/reports/FBgn0052450 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH25462, BcDNA:GH25462, anon-WO0140519.221, CG32450" - CG32450 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0083237 EP2589 EP2589 http://flybase.org/reports/FBgn0083237 gene - - - EP2589 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084937 3.1.38 3.1.38 http://flybase.org/reports/FBgn0084937 gene - - - 3.1.38 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0058390 CG40390 - http://flybase.org/reports/FBgn0058390 protein_coding_gene - - - CG40390 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066339 mus313 mus313 http://flybase.org/reports/FBgn0066339 gene - - - mus313 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0014294 l(3)64Be lethal (3) 64Be http://flybase.org/reports/FBgn0014294 - gene - - - l(3)64Be - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0046887 Gr98b Gustatory receptor 98b http://flybase.org/reports/FBgn0046887 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to L-canavanine ; GO:1901354 | inferred from mutant phenotype response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr98A1, CG12884, Gr98B2, 98B.2, GR98B.2, CG31059, Gr98b, GR98b" IPR013604:7TM chemoreceptor CG31059 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0263570 mir-4941 mir-4941 stem loop http://flybase.org/reports/FBgn0263570 miRNA_gene - - - "mir-4941, dme-mir-4941, CR43555" - CR43555 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050361 mtt mangetout http://flybase.org/reports/FBgn0050361 protein_coding_gene glutamate binding ; GO:0016595 | NOT inferred from sequence or structural similarity inferred from direct assay glutamate receptor activity ; GO:0008066 | NOT inferred from direct assay G-protein coupled receptor activity ; GO:0004930 | inferred from direct assay glutamate receptor activity ; GO:0008066 | inferred from biological aspect of ancestor with PANTHER:PTN001173581 "adult feeding behavior ; GO:0008343 | inferred from mutant phenotype response to insecticide ; GO:0017085 | inferred from direct assay inferred from mutant phenotype phospholipase C-activating G-protein coupled receptor signaling pathway ; GO:0007200 | inferred from direct assay regulation of synaptic transmission, glutamatergic ; GO:0051966 | inferred from biological aspect of ancestor with PANTHER:PTN001173581 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway ; GO:0007196 | inferred from biological aspect of ancestor with PANTHER:PTN001527784" integral component of plasma membrane ; GO:0005887 | inferred from direct assay presynaptic membrane ; GO:0042734 | inferred from biological aspect of ancestor with PANTHER:PTN001527784 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001173583 dendrite ; GO:0030425 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mGluR "CG30361, DmGluBR, DmXR, CG8692, GluRB, DmGluRB, CG18447, Glu-RB, anon-WO0170980.5, anon-WO0170980.4, mtt, mXr" "IPR017978:GPCR family 3, C-terminal, IPR017979:GPCR, family 3, conserved site, IPR000162:GPCR, family 3, metabotropic glutamate receptor, IPR000337:GPCR, family 3, IPR001828:Receptor, ligand binding region, IPR011500:GPCR, family 3, nine cysteines domain, IPR028082:Periplasmic binding protein-like I" CG30361 11-Aug-17 DroID_v2017_08 "Drer\grm4, Drer\grm1b, Drer\tas1r2.1, Drer\grm3, Drer\grm6b, Drer\grm6a, Drer\LOC103911572, Drer\tas1r1, Drer\grm5a, Drer\grm2a, Drer\tas1r3, Drer\grm8a, Drer\grm5b, Drer\grm8b, Drer\grm2b, Drer\grm1a" - "Cele\mgl-1, Cele\F35H10.10, Cele\mgl-3, Cele\C30A5.10, Cele\mgl-2" "Xtro\grm5, Xtro\grm3, Xtro\grm8, Xtro\grm1, Xtro\grm7, Xtro\grm4" "Mmus\Grm8, Mmus\Grm7, Mmus\Grm4, Mmus\Grm1, Mmus\Grm6, Mmus\Tas1r1, Mmus\Tas1r2, Mmus\Grm5, Mmus\Tas1r3, Mmus\Grm2, Mmus\Grm3, Mmus\Casr" "Hsap\GRM1, Hsap\GRM3, Hsap\GRM5, Hsap\GRM6, Hsap\TAS1R3, Hsap\GRM8, Hsap\GRM4, Hsap\TAS1R1, Hsap\GRM2, Hsap\CASR, Hsap\TAS1R2, Hsap\GRM7" "viable,feeding behavior defective,recessive" FBgn0058063 CG40063 - http://flybase.org/reports/FBgn0058063 protein_coding_gene - - - CG40063 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263271 CG43397 - http://flybase.org/reports/FBgn0263271 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43397 - CG43397 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069974 CG40484 - http://flybase.org/reports/FBgn0069974 protein_coding_gene - - - CG40484 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038097 CG14384 - http://flybase.org/reports/FBgn0038097 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14384 - CG14384 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0013350 dUTPase-i Deoxyuridine triphosphatase-inhibitor http://flybase.org/reports/FBgn0013350 - gene dUTP pyrophosphatase inhibitor activity ; GO:0004858 | traceable author statement - - "UTPase-i, dUTPase-i" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065740 l(2)SH0527 lethal (2) SH0527 http://flybase.org/reports/FBgn0065740 gene - - - "l(2)SH0527, l(2)SH2 0527" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266111 ana3 anastral spindle 3 http://flybase.org/reports/FBgn0266111 protein_coding_gene - centriole replication ; GO:0007099 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype centriole-centriole cohesion ; GO:0010457 | inferred from mutant phenotype ciliary basal body organization ; GO:0032053 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay ciliary basal body ; GO:0036064 | inferred from direct assay "Ana3, ana3, CG13162, l(2)SH0558" "IPR030791:Rotatin, IPR029249:Rotatin, N-terminal, IPR011989:Armadillo-like helical" CG13162 11-Aug-17 DroID_v2017_08 Drer\rttn - - - Mmus\Rttn Hsap\RTTN FBgn0033757 muskelin muskelin http://flybase.org/reports/FBgn0033757 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cell-matrix adhesion ; GO:0001952 | inferred from sequence or structural similarity with MGI:MGI:1351638 oocyte maturation ; GO:0001556 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:1351638 "DmMK, CG8811, muskelin" "IPR006594:LIS1 homology motif, IPR006595:CTLH, C-terminal LisH motif, IPR008979:Galactose-binding domain-like, IPR010565:Muskelin, N-terminal, IPR015915:Kelch-type beta propeller, IPR015916:Galactose oxidase, beta-propeller, IPR006652:Kelch repeat type 1" CG8811 11-Aug-17 DroID_v2017_08 Drer\mkln1 - - Xtro\mkln1 Mmus\Mkln1 Hsap\MKLN1 "viable,fertile" FBgn0053243 Ste:CG33243 Ste:CG33243 http://flybase.org/reports/FBgn0053243 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG32605, CG33243, Ste:CG33243" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33243 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0065549 l(2)SH1042 lethal (2) SH1042 http://flybase.org/reports/FBgn0065549 gene - - - "l(2)SH1042, l(2)SH2 1042" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265319 tio::tsh - http://flybase.org/reports/FBgn0265319 engineered_fusion_gene - - - "tio::tsh, Tsh/Tio" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,ectopic,antennal disc,somatic clone,ventral" FBgn0065868 l(2)SH0261 lethal (2) SH0261 http://flybase.org/reports/FBgn0065868 gene - - - l(2)SH0261 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0084285 l(3)S026421 l(3)S026421 http://flybase.org/reports/FBgn0084285 gene - - - l(3)S026421 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283545 vilya vilya http://flybase.org/reports/FBgn0283545 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 positive regulation of meiotic DNA double-strand break formation ; GO:1903343 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype site of double-strand break ; GO:0035861 | inferred from direct assay recombination nodule ; GO:0005713 | inferred from direct assay central element ; GO:0000801 | inferred from direct assay "Vilya, EG:95B7.5, CG2709, mei-826, vilya" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2709 11-Aug-17 DroID_v2017_08 - Scer\CST9 "Cele\Y39B6A.16, Cele\F55A12.10, Cele\zhp-3, Cele\D1081.9, Cele\col-80" - - "Hsap\RNF212B, Hsap\ZCCHC14" "viable,fertile" FBgn0042132 CG18809 - http://flybase.org/reports/FBgn0042132 protein_coding_gene - determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype - "CG18809, CG1809" - CG18809 11-Aug-17 DroID_v2017_08 Drer\si:ch73-152o7.1 - - Xtro\c19orf43 Mmus\2310036O22Rik Hsap\C19orf43 "long lived,female,RU486 conditional,viable" FBgn0259818 CG42399 - http://flybase.org/reports/FBgn0259818 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG42399, CG11620, CG4648" "IPR016024:Armadillo-type fold, IPR024395:CLASP N-terminal domain, IPR034085:TOG domain, IPR011989:Armadillo-like helical" CG42399 11-Aug-17 DroID_v2017_08 - - Cele\che-12 - "Mmus\Fam179a, Mmus\Fam179b" "Hsap\FAM179B, Hsap\FAM179A" DRSC00322 K 0.084648327 0.413390698 0.153032731 0.343758312 0.979525903 -1.520379021 FBgn0002606 M(2)58F Minute (2) 58F http://flybase.org/reports/FBgn0002606 - gene - - - "M(2)l, M(2R)l, Ml, M[[l']], M(2)58F" - - 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,dominant,visible,Minute,small body,lethal - all die before end of larval stage,recessive,some die during larval stage" "macrochaeta,posterior dorsocentral bristle,posterior scutellar bristle,femur & macrochaeta,eye" FBgn0069129 mei(2)yoh7134 mei(2)yoh7134 http://flybase.org/reports/FBgn0069129 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(2)yoh7134 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0051339 CR31339 - http://flybase.org/reports/FBgn0051339 non_protein_coding_gene - - - CR31339 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22960 K -0.966555257 1.077934321 -0.094877528 -0.100327325 0.092900065 2.179497644 FBgn0069155 mcl(3)Z2592 mcl(3)Z2592 http://flybase.org/reports/FBgn0069155 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z2592 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0011888 tRNA:Lys-CTT-1-3 transfer RNA:Lysine-CTT 1-3 http://flybase.org/reports/FBgn0011888 "FBgn0003795, FBgn0011886, FBgn0050311, FBgn0050516, FBgn0060187" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "35SLys, tRNA Lys, tRNA[Lys][[2]], AE002769.trna4-LysCTT, tRNA:K2, tRNA:K:CTT:AE002769-b, tRNA:lys2:42Ab, CR30311, CR30516, tRNAlys, chr2R.trna95-LysCTT, tRNA-Lys-CTT-1-3, tRNA:Lys-CTT-1-3, tRNA:K2:42Ab, AAG" - CR30516 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265541 CR44391 - http://flybase.org/reports/FBgn0265541 pseudogene_attribute - - - CR44391 - CR44391 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085205 CG34176 - http://flybase.org/reports/FBgn0085205 protein_coding_gene - - - CG34176 - CG34176 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005553 l(3)85Ff lethal (3) 85Ff http://flybase.org/reports/FBgn0005553 - gene - - - l(3)85Ff - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260622 2L2686 - http://flybase.org/reports/FBgn0260622 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2686 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0084033 CG41473 - http://flybase.org/reports/FBgn0084033 protein_coding_gene - - - CG41473 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040491 Buffy Buffy http://flybase.org/reports/FBgn0040491 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cellular response to starvation ; GO:0009267 | inferred from mutant phenotype programmed cell death ; GO:0012501 | traceable author statement ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype positive regulation of programmed cell death ; GO:0043068 | inferred from mutant phenotype inferred from genetic interaction with grim apoptotic process ; GO:0006915 | inferred from sequence or structural similarity with HGNC:990 negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype inferred from genetic interaction with hid inferred from genetic interaction with rpr inferred from genetic interaction with grim inferred from genetic interaction with Diap1 regulation of apoptotic process ; GO:0042981 | traceable author statement positive regulation of macroautophagy ; GO:0016239 | inferred from mutant phenotype apoptotic process ; GO:0006915 | non-traceable author statement endoplasmic reticulum ; GO:0005783 | inferred from direct assay "Buffy, Buffy/Borg2, buffy, Buffy/dBorg-2, CG8238, dBorg-2, dBORG-2/BUFFY, Buffy/DBorg-2, Dbx, Bcl-2-48AE, dbuffy, dBorg2, BUFFY, Drob2" "IPR002475:Bcl2-like, IPR026309:Bcl-2-related ovarian killer protein, IPR026298:Blc2 family" CG8238 11-Aug-17 DroID_v2017_08 "Drer\mcl1a, Drer\boka, Drer\bcl2a, Drer\mcl1b, Drer\bcl2l1, Drer\bcl2b, Drer\bokb" - Cele\ced-9 "Xtro\mcl1, Xtro\bcl2, Xtro\bcl2l2, Xtro\bcl2l1, Xtro\bok" "Mmus\Bcl2, Mmus\Bok, Mmus\Bcl2a1c, Mmus\Bcl2a1d, Mmus\Mcl1, Mmus\Bcl2a1b, Mmus\Bak1, Mmus\Bcl2a1a, Mmus\Bcl2l1, Mmus\Bcl2l14, Mmus\Pabpn1" "Hsap\BCL2, Hsap\BCL2L2, Hsap\BOK, Hsap\MCL1, Hsap\BCL2L2-PABPN1, Hsap\BCL2L1, Hsap\BCL2L14, Hsap\BCL2A1, Hsap\BAK1" pupal stage salivary gland

"viable,fertile,increased cell death,decreased cell death,conditional,mitotic cell cycle defective,lethal,partially,short lived" "presumptive embryonic/larval nervous system,glial cell" FBgn0060342 l(3)S143907 lethal (3) S143907 http://flybase.org/reports/FBgn0060342 gene - - - "1439/07, l(3)S143907" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0012002 tRNA:Val-CAC-1-1 transfer RNA:Valine-CAC 1-1 http://flybase.org/reports/FBgn0012002 "FBgn0011997, FBgn0051572, FBgn0060022" tRNA_gene GUG codon-amino acid adaptor activity ; GO:0033452 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033452 cytosol ; GO:0005829 | inferred by curator from GO:0033452 "valine tRNA, Val, tRNA[Val][[3b]], AE002708.trna9-ValCAC, tRNA:V3b, tRNA:V:CAC:AE002708-a, tRNA:val3b:90BC, CR31572, chr3R.trna15-ValCAC, tRNA:Val-CAC-1-1, tRNA:V3b:90BC, tRNA-Val-CAC-1-1, GUG" - CR31572 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039273 shams shams http://flybase.org/reports/FBgn0039273 protein_coding_gene xylosyltransferase activity ; GO:0042285 | inferred from direct assay negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype inferred from genetic interaction with N - "shams, CG9996, dibeta3GnT5" "IPR002495:Glycosyl transferase, family 8, IPR029044:Nucleotide-diphospho-sugar transferases" CG9996 11-Aug-17 DroID_v2017_08 "Drer\gxylt2, Drer\b4gat1, Drer\gxylt1a, Drer\gxylt1b, Drer\large, Drer\xxylt1" - Cele\lge-1 "Xtro\gxylt1, Xtro\xxylt1, Xtro\b4gat1, Xtro\gyltl1b, Xtro\gxylt2, Xtro\large" "Mmus\B4gat1, Mmus\Gxylt1, Mmus\Xxylt1, Mmus\Large1, Mmus\Gxylt2, Mmus\Large2" "Hsap\B4GAT1, Hsap\LARGE1, Hsap\GXYLT2, Hsap\LARGE2, Hsap\GXYLT1, Hsap\XXYLT1" "viable,fertile" FBgn0085635 CG41370 - http://flybase.org/reports/FBgn0085635 protein_coding_gene - - - CG41370 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030061 CG1785 - http://flybase.org/reports/FBgn0030061 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG1785 IPR011687:Ribosome biogenesis protein Nop53/GLTSCR2 CG1785 11-Aug-17 DroID_v2017_08 Drer\gltscr2 Scer\NOP53 Cele\Y39B6A.33 Xtro\gltscr2 Mmus\Gltscr2 Hsap\GLTSCR2 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0032074 Tsp29Fa Tetraspanin 29Fa http://flybase.org/reports/FBgn0032074 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "CG9494, Dm.Tsp29Fa, Tsp29Fa" "IPR018499:Tetraspanin/Peripherin, IPR018503:Tetraspanin, conserved site, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG9494 11-Aug-17 DroID_v2017_08 "Drer\tspan4b, Drer\cd63, Drer\cd151l, Drer\tspan11, Drer\tspan7b, Drer\tspan7, Drer\cd151" - "Cele\tsp-7, Cele\tsp-3, Cele\tsp-14, Cele\tsp-2, Cele\tsp-1" "Xtro\cd63, Xtro\tspan6, Xtro\cd151" "Mmus\Tspan6, Mmus\Tspan11, Mmus\Cd151, Mmus\Cd63, Mmus\Tspan7" "Hsap\TSPAN7, Hsap\CD151, Hsap\TSPAN6, Hsap\CD63, Hsap\TSPAN11" viable FBgn0003527 stil stand still http://flybase.org/reports/FBgn0003527 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism development ; GO:0007275 | inferred from mutant phenotype female sex differentiation ; GO:0046660 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype female sex determination ; GO:0030237 | inferred from mutant phenotype nuclear chromatin ; GO:0000790 | inferred from direct assay "152072_at, Y10276, CG8592, stil, Stil" - CG8592 11-Aug-17 DroID_v2017_08 - - - - - - adult stage && oogenesis stage " nurse cell

, germarium

" " larval stage | third instar , adult stage | female && oogenesis stage , larval stage | first instar , adult stage | male , embryonic stage | stage >=11 , larval stage | second instar , adult stage && oogenesis stage | stage S1-13 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-10 " " spermatogonium

, germline cell

, spermatocyte

, male germline stem cell

, primary spermatocyte cyst

, nurse cell

, ovary

, testis | restricted

, oocyte

" "viable,fertile,wild-type,lethal,heat sensitive,sex-determination defective,recessive,female sterile" "ovary,germline cell,female,egg chamber,dorsal appendage,chorion,oocyte" FBgn0085243 CG34214 - http://flybase.org/reports/FBgn0085243 protein_coding_gene - - - "CG34214, Dm_2R:92173" - CG34214 11-Aug-17 DroID_v2017_08 Drer\rbm28 Scer\NOP4 - Xtro\rbm28 Mmus\Rbm28 Hsap\RBM28 FBgn0084521 l(3)S046604 l(3)S046604 http://flybase.org/reports/FBgn0084521 gene - - - l(3)S046604 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028857 CG12448 - http://flybase.org/reports/FBgn0028857 protein_coding_gene myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis - - "BG:DS07486.4, CG12448" "IPR000048:IQ motif, EF-hand binding site" CG12448 11-Aug-17 DroID_v2017_08 Drer\spata17 - - - Mmus\Spata17 Hsap\SPATA17 viable FBgn0266050 CG44815 - http://flybase.org/reports/FBgn0266050 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44815 - CG44815 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266207 CR44902 - http://flybase.org/reports/FBgn0266207 non_protein_coding_gene - - - CR44902 - CR44902 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013719 pbr postscutellar bristles http://flybase.org/reports/FBgn0013719 - gene - - - "psb, pbr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" FBgn0067867 Mod(Prat:bw)3-8 Mod(Prat:bw)3-8 http://flybase.org/reports/FBgn0067867 gene - - - "Mod-3-8, Mod(Prat:bw)3-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065982 iab-5E.s iab-5E.s http://flybase.org/reports/FBgn0065982 gene - - - "iab-5E s, iab-5E.s, IAB5, 5E" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022122 l(2)k06608b lethal (2) k06608b http://flybase.org/reports/FBgn0022122 - gene - - - l(2)k06608b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261534 l(2)34Fc lethal (2) 34Fc http://flybase.org/reports/FBgn0261534 protein_coding_gene - negative regulation of immune response ; GO:0050777 | inferred from mutant phenotype defense response to protozoan ; GO:0042832 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:Q0Q029 "l(2)34Fc, CG7532, l(2)br8, l34Fc, br8, A2, DS01068.5, BG:DS01068.5, anon-EST:ParkEST060, BcDNA:RE60882" IPR002861:Reeler domain CG7532 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-14h1.2, Drer\si:dkey-251i10.2, Drer\si:ch73-196i15.5" - "Cele\M03A1.3, Cele\C05D12.1" - Mmus\Frrs1 Hsap\FRRS1 FBgn0260859 Bet3 Blocked early in transport 3 http://flybase.org/reports/FBgn0260859 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000001776 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000001776 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000001776 dsRNA transport ; GO:0033227 | inferred from mutant phenotype TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000001776 cytoplasm ; GO:0005737 | inferred from direct assay "CG3911, BET3, Bet3p, Bet3, dBet3" "IPR007194:Transport protein particle (TRAPP) component, IPR016721:Bet3 family, IPR024096:NO signalling/Golgi transport ligand-binding domain" CG3911 11-Aug-17 DroID_v2017_08 Drer\trappc3 Scer\BET3 Cele\trpp-3 Xtro\trappc3 "Mmus\Trappc3, Mmus\Trappc3l" "Hsap\TRAPPC3, Hsap\TRAPPC3L" FBgn0051164 Ir94a Ionotropic receptor 94a http://flybase.org/reports/FBgn0051164 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir94a, DmelIR94a, CG31164, IR94a" - CG31164 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060566 l(3)S096512 lethal (3) S096512 http://flybase.org/reports/FBgn0060566 gene - - - "0965/12, l(3)S096512" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039501 CG5987 - http://flybase.org/reports/FBgn0039501 protein_coding_gene - cellular protein modification process ; GO:0006464 | inferred from electronic annotation with InterPro:IPR004344 - CG5987 IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase CG5987 11-Aug-17 DroID_v2017_08 "Drer\ttll6, Drer\ttll11, Drer\ttll7" - Cele\ttll-11 "Xtro\ttll7, Xtro\ttll11" "Mmus\Ttll6, Mmus\Ttll13, Mmus\Ttll7, Mmus\Ttll11, Mmus\Kprp" "Hsap\TTLL7, Hsap\KPRP, Hsap\TTLL11, Hsap\TTLL6, Hsap\NGRN" viable FBgn0037958 CG6962 - http://flybase.org/reports/FBgn0037958 protein_coding_gene sphingomyelin phosphodiesterase D activity ; GO:0050290 | inferred from electronic annotation with InterPro:IPR024129 - - CG6962 IPR024129:Sphingomyelin phosphodiesterase 4 CG6962 11-Aug-17 DroID_v2017_08 Drer\smpd4 - Cele\R05D11.9 Xtro\smpd4 Mmus\Smpd4 Hsap\SMPD4 "viable,fertile" DRSC16153 E 0.329211786 0.493030602 0.603497637 -1.911813895 -0.499866218 -0.389856999 FBgn0052449 tRNA:Cys-GCA-4-1 transfer RNA:Cysteine-GCA 4-1 http://flybase.org/reports/FBgn0052449 tRNA_gene UGC codon-amino acid adaptor activity ; GO:0033414 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033414 cytosol ; GO:0005829 | inferred by curator from GO:0033414 "AE002647.trna3-CysGCA, tRNA:C:GCA:AE002647, CR32449, chr3L.trna34-CysGCA, tRNA:Cys-GCA-4-1, tRNA:CR32449, tRNA-Cys-GCA-4-1, UGC" - CR32449 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261867 hby homebody http://flybase.org/reports/FBgn0261867 gene - larval foraging behavior ; GO:0035177 | inferred from mutant phenotype - hby - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038925 Cchl Cytochrome c heme lyase http://flybase.org/reports/FBgn0038925 protein_coding_gene holocytochrome-c synthase activity ; GO:0004408 | inferred from biological aspect of ancestor with PANTHER:PTN000297201 holocytochrome-c synthase activity ; GO:0004408 | inferred from sequence or structural similarity with UniProtKB:P53701 cytochrome c-heme linkage ; GO:0018063 | inferred from biological aspect of ancestor with PANTHER:PTN000297201 cytochrome c-heme linkage ; GO:0018063 | inferred from sequence or structural similarity with UniProtKB:P53701 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:P53701 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000297201 "Cchl, CG6022, cchl, cchL" IPR000511:Cytochrome c/c1 haem-lyase CG6022 11-Aug-17 DroID_v2017_08 "Drer\hccsa.1, Drer\hccsb, Drer\hccsa.2" "Scer\CYT2, Scer\CYC3" Cele\cchl-1 Xtro\hccs Mmus\Hccs Hsap\HCCS "visible,recessive,somatic clone,lethal,viable" "eye,somatic clone,eye disc,trichogen cell,mesothoracic tergum" FBgn0004897 fd96Ca forkhead domain 96Ca http://flybase.org/reports/FBgn0004897 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000930792 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "CG11921, Dmfd4, FD4, fd4, fd96Ca" "IPR018122:Fork head domain conserved site1, IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG11921 11-Aug-17 DroID_v2017_08 "Drer\foxb2, Drer\si:ch211-262e15.1, Drer\foxd2, Drer\foxl1, Drer\foxk2, Drer\foxj1a, Drer\foxk1, Drer\foxb1b, Drer\foxq2, Drer\foxg1a, Drer\foxb1a, Drer\foxd3" "Scer\FKH1, Scer\HCM1, Scer\FKH2" "Cele\let-381, Cele\fkh-10, Cele\unc-130, Cele\fkh-2, Cele\lin-31" "Xtro\foxi4.2, Xtro\foxj1.2, Xtro\foxd4l1.1, Xtro\foxd1, Xtro\foxb1, Xtro\foxj1, Xtro\foxd4l1.2, Xtro\foxd2, Xtro\foxd3, Xtro\foxk2" "Mmus\Foxj1, Mmus\Foxk2, Mmus\Foxk1, Mmus\Foxb1, Mmus\Foxd3, Mmus\Foxl1, Mmus\Foxg1, Mmus\Foxb2" "Hsap\FOXK2, Hsap\FOXD4, Hsap\FOXA3, Hsap\FOXG1, Hsap\FOXB2, Hsap\FOXL1, Hsap\FOXK1, Hsap\FOXD3, Hsap\FOXB1, Hsap\FOXJ1" embryonic stage " sensory neuron

, neuroblast

, head

, embryonic peripheral nervous system

" viable DRSC16946 E -0.211455591 -1.456618165 -0.273410425 -1.680186769 -0.015161358 -0.003099701 FBgn0069060 EP-M269 BEST:RE41386 http://flybase.org/reports/FBgn0069060 gene - - - "EST:RE41386, EP-M269, BEST:RE41386" - - 11-Aug-17 DroID_v2017_08 - - - - - - "ventral nerve cord commissure,longitudinal connective" FBgn0046710 GIIIB GIIIB http://flybase.org/reports/FBgn0046710 gene phospholipase A2 activity ; GO:0004623 | non-traceable author statement - extracellular region ; GO:0005576 | non-traceable author statement "dGIIIB, GIIIB" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052703 Erk7 Extracellularly regulated kinase 7 http://flybase.org/reports/FBgn0052703 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR003527 MAP kinase activity ; GO:0004707 | inferred from biological aspect of ancestor with PANTHER:PTN000622871 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype negative regulation of peptide hormone secretion ; GO:0090278 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:P21708 protein phosphorylation ; GO:0006468 | non-traceable author statement negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 negative regulation of protein secretion ; GO:0050709 | inferred from mutant phenotype negative regulation of multicellular organism growth ; GO:0040015 | inferred from genetic interaction with RIOK2 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype nuclear envelope ; GO:0005635 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay "CG32703, ERK7, CG2309, CG17441, Erk7" "IPR000719:Protein kinase domain, IPR003527:Mitogen-activated protein (MAP) kinase, conserved site, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG32703 11-Aug-17 DroID_v2017_08 "Drer\mapk12a, Drer\zgc:171775, Drer\mapk11, Drer\mapk7, Drer\mapk12b, Drer\mapk14a, Drer\mapk15, Drer\mapk3, Drer\mapk14b, Drer\mapk6, Drer\mapk4, Drer\mapk1, Drer\mapk13" "Scer\FUS3, Scer\SMK1, Scer\KSS1, Scer\KDX1, Scer\HOG1, Scer\SLT2" Cele\C05D10.2 "Xtro\mapk15, Xtro\mapk1, Xtro\mapk6, Xtro\LOC100145045, Xtro\mapk14, Xtro\mapk4, Xtro\mapk7, Xtro\mapk12, Xtro\mapk11" "Mmus\Mapk14, Mmus\Mapk3, Mmus\Mapk6, Mmus\Mapk15, Mmus\Mapk4, Mmus\Mapk13, Mmus\Mapk1, Mmus\Mapk11, Mmus\Mapk12, Mmus\Mapk7" "Hsap\MAPK4, Hsap\MAPK6, Hsap\MAPK15, Hsap\MAPK11, Hsap\RPS6KA2, Hsap\MAPK1, Hsap\MAPK13, Hsap\MAPK14, Hsap\MAPK12, Hsap\MAPK3, Hsap\MAPK7" viable FBgn0054041 CG34041 - http://flybase.org/reports/FBgn0054041 protein_coding_gene "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 molecular_function ; GO:0003674 | no biological data available" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR013547 biological_process ; GO:0008150 | no biological data available endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 cellular_component ; GO:0005575 | no biological data available "BP1033, CG31018, CG34041" "IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR011990:Tetratricopeptide-like helical domain, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG34041 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\p4ha3, Drer\p4ha1a, Drer\zgc:158254, Drer\p4htm, Drer\zgc:152670, Drer\p4ha2" - "Cele\Y43F8B.19, Cele\C14E2.4, Cele\dpy-18, Cele\phy-2, Cele\phy-3" "Xtro\p4ha2, Xtro\p4ha1, Xtro\p4ha3" "Mmus\P4ha3, Mmus\P4ha1, Mmus\P4ha2, Mmus\P4htm" "Hsap\P4HTM, Hsap\P4HA3, Hsap\P4HA2, Hsap\P4HA1" FBgn0263290 CR43399 - http://flybase.org/reports/FBgn0263290 non_protein_coding_gene - - - CR43399 - CR43399 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038686 CG5555 - http://flybase.org/reports/FBgn0038686 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001607, InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:1099 zinc ion binding ; GO:0008270 | inferred from sequence model" protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:1099 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:1099 CG5555 "IPR001607:Zinc finger, UBP-type, IPR001841:Zinc finger, RING-type, IPR011422:BRCA1-associated 2, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5555 11-Aug-17 DroID_v2017_08 Drer\brap Scer\ETP1 Cele\brap-2 Xtro\brap "Mmus\Brap, Mmus\Amfr" "Hsap\BRAP, Hsap\AMFR, Hsap\TRIM39" "visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval hemocyte | third instar larval stage,trichogen cell,mesothoracic tergum" FBgn0040115 l(2)23Db lethal (2) 23Db http://flybase.org/reports/FBgn0040115 gene - - - l(2)23Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259917 CG42446 - http://flybase.org/reports/FBgn0259917 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42446 - CG42446 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266972 CR45423 - http://flybase.org/reports/FBgn0266972 non_protein_coding_gene - - - "CR45423, CR44454, CR44637" - CR45423 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000345 com-d compressed dilapidator http://flybase.org/reports/FBgn0000345 - gene - - - com-d - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "leg,wing" FBgn0017432 anon-4Bb anon-4Bb http://flybase.org/reports/FBgn0017432 - gene - - - anon-4Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031049 Sec61gamma Sec61 gamma subunit http://flybase.org/reports/FBgn0031049 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from electronic annotation with InterPro:IPR008158 protein targeting ; GO:0006605 | inferred from electronic annotation with InterPro:IPR001901 negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001901, InterPro:IPR008158" "CG14214, Sec61gamma, Sec61" "IPR001901:Protein translocase complex, SecE/Sec61-gamma subunit, IPR008158:Protein translocase SEC61 complex, gamma subunit, IPR023391:Protein translocase SecE domain, IPR022943:Preprotein translocase subunit SecE" CG14214 11-Aug-17 DroID_v2017_08 Drer\sec61g "Scer\CHL4, Scer\SSS1" Cele\emo-1 Xtro\sec61g "Mmus\Gm12881, Mmus\LOC102637269, Mmus\Gm4184, Mmus\Sec61g" Hsap\SEC61G "lethal,lethal - all die before end of pupal stage,some die during pupal stage" "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0267297 CR45733 - http://flybase.org/reports/FBgn0267297 non_protein_coding_gene - - - CR45733 - CR45733 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000473 Cyp6a2 Cytochrome P450-6a2 http://flybase.org/reports/FBgn0000473 FBgn0010312 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 response to caffeine ; GO:0031000 | inferred from direct assay response to DDT ; GO:0046680 | inferred from mutant phenotype" - "143127_at, cyp6a2, CYP6A2, 6a2, Cyp6A2, P450, 91-R, 91R, P-450, P450-B1, P-450-B, P450-B, Cyt-P450-B1, CG9438, Cyp6a2, Cyp6a, CYP6a2" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG9438 11-Aug-17 DroID_v2017_08 "Drer\cyp3c4, Drer\cyp4f3, Drer\tbxas1, Drer\cyp4v7, Drer\cyp3c3, Drer\cyp3c2, Drer\cyp4t8, Drer\cyp4v8, Drer\cyp3a65, Drer\cyp3c1" Scer\ERG11 "Cele\cyp-42A1, Cele\cyp-25A1, Cele\cyp-25A4, Cele\cyp-32B1, Cele\cyp-13B1, Cele\cyp-25A6, Cele\cyp-13A5, Cele\cyp-31A3, Cele\cyp-44A1, Cele\cyp-35B1, Cele\cyp-13A3, Cele\cyp-29A3, Cele\cyp-13A6, Cele\cyp-25A3, Cele\cyp-29A4, Cele\cyp-25A2, Cele\cyp-13A4, Cele\cyp-13A7, Cele\cyp-13A11, Cele\cyp-13A2, Cele\cyp-32A1, Cele\cyp-13A8, Cele\cyp-31A2, Cele\cyp-29A2, Cele\cyp-13B2, Cele\cyp-13A12, Cele\cyp-37B1, Cele\cyp-13A1, Cele\cyp-13A10, Cele\cyp-43A1" "Xtro\LOC100494419, Xtro\tbxas1, Xtro\cyp3a4, Xtro\cyp3a5" "Mmus\Cyp4a32, Mmus\Cyp4a12a, Mmus\Cyp4f39, Mmus\Cyp3a41a, Mmus\Cyp3a11, Mmus\Cyp4b1, Mmus\Cyp3a57, Mmus\Cyp3a59, Mmus\Cyp4a31, Mmus\Cyp3a41b, Mmus\Cyp4a12b, Mmus\Cyp3a13, Mmus\Cyp4f18, Mmus\Cyp4f14, Mmus\Cyp3a44, Mmus\Cyp4v3, Mmus\Cyp4f37, Mmus\Tbxas1, Mmus\Cyp4a14, Mmus\Cyp4f16, Mmus\Cyp3a25, Mmus\Cyp3a16, Mmus\Cyp4f15, Mmus\Cyp4a10, Mmus\Cyp4f13" "Hsap\CYP4Z1, Hsap\CYP4A11, Hsap\CYP3A43, Hsap\CYP4F11, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4F22, Hsap\CYP4F12, Hsap\CYP4F8, Hsap\CYP4A22, Hsap\CYP4B1, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\CYP4V2, Hsap\CYP4F3, Hsap\CYP3A4, Hsap\CYP4F2, Hsap\CYP4X1, Hsap\TBXAS1" "chemical resistant,chemical sensitive,viable" FBgn0034049 bdg bedraggled http://flybase.org/reports/FBgn0034049 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT neurotransmitter transport ; GO:0006836 | inferred from sequence model transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype inferred from genetic interaction with dsh inferred from genetic interaction with Vang inferred from genetic interaction with stan inferred from genetic interaction with dgo integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model "bdg, CG8291" IPR000175:Sodium:neurotransmitter symporter CG8291 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-132b12.3, Drer\slc6a9, Drer\slc6a14, Drer\zgc:174946, Drer\si:ch211-132b12.1, Drer\slc6a11a, Drer\slc6a13, Drer\slc6a13l, Drer\si:ch211-132b12.2, Drer\si:ch211-132b12.6" "Scer\ZDS1, Scer\IRR1" "Cele\asp-2, Cele\F56F4.3, Cele\snf-5, Cele\snf-2, Cele\snf-9, Cele\snf-6, Cele\snf-7" Xtro\slc6a13 "Mmus\Bach1, Mmus\Slc6a14, Mmus\Slc6a9" "Hsap\SLC6A9, Hsap\SLC6A14" "planar polarity defective,lethal,recessive,uncoordinated,locomotor behavior defective,flightless,viable" "ommatidium,eye photoreceptor cell,antennal disc,eye disc,somatic clone" DRSC07136 I -0.588875522 -2.53956738 -0.574093469 0.242152711 0.914409732 -0.067525446 FBgn0030903 CG15060 - http://flybase.org/reports/FBgn0030903 protein_coding_gene - - - CG15060 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC19634 IEK -0.468898151 -4.736403253 -0.944840268 -5.53699024 -4.030046297 -5.193921646 FBgn0001503 l(1)10Da lethal (1) 10Da http://flybase.org/reports/FBgn0001503 FBgn0001862 gene - - - l(1)10Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect,partially lethal - majority die" "egg,germline clone" FBgn0003450 snk snake http://flybase.org/reports/FBgn0003450 FBgn0015383 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type peptidase activity ; GO:0008236 | non-traceable author statement serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model peptidase activity ; GO:0008233 | traceable author statement" "Toll signaling pathway ; GO:0008063 | non-traceable author statement Toll signaling pathway ; GO:0008063 | inferred from genetic interaction with Tl dorsal/ventral axis specification ; GO:0009950 | non-traceable author statement protein processing ; GO:0016485 | inferred from genetic interaction with ea dorsal/ventral axis specification ; GO:0009950 | traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | traceable author statement proteolysis ; GO:0006508 | traceable author statement proteolysis ; GO:0006508 | inferred from sequence model" extracellular region ; GO:0005576 | traceable author statement "SP26, c-SP26, CG7996, me(3)4, l(3)87Dg, snk, SNK, Snk" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site, IPR022700:Proteinase, regulatory CLIP domain" CG7996 11-Aug-17 DroID_v2017_08 - - Cele\try-3 - "Mmus\Prss12, Mmus\Hgfac, Mmus\Plat, Mmus\Habp2, Mmus\Plau, Mmus\F12, Mmus\Egfbp2, Mmus\Mcpt4" Hsap\CMA1 embryonic stage | 0-4 hr "wild-type,female sterile,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,lethal,maternal effect,viable" "embryonic/first instar larval cuticle,maternal effect,ventral,denticle belt,filzkorper" FBgn0052725 CG32725 - http://flybase.org/reports/FBgn0052725 protein_coding_gene - - - CG32725 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043049 anon-60Ad anon-60Ad http://flybase.org/reports/FBgn0043049 gene - - - anon-60Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020524 ms(3)CB27 ms(3)CB27 http://flybase.org/reports/FBgn0020524 - gene - - - ms(3)CB27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0026236 kugi kugi http://flybase.org/reports/FBgn0026236 - gene - - - "homr, kugi" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001072 Fs(3)Zol Female sterile (3) Zolta http://flybase.org/reports/FBgn0001072 - gene - - - "Fs(3)Zolta, Fs(3)Sz32, Fs(3)Zol" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0026634 ldlCp ldlCp-related protein http://flybase.org/reports/FBgn0026634 - protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000311229 protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR009316 dsRNA transport ; GO:0033227 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from sequence or structural similarity with UniProtKB:Q14746 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000311229 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000311229 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR009316 Golgi transport complex ; GO:0017119 | inferred from direct assay "ldlCp, CG6177, ldl-Cp, Cog2" "IPR009316:COG complex component, COG2, IPR024602:Conserved oligomeric Golgi complex, subunit 2, N-terminal, IPR024603:COG complex component, COG2, C-terminal, IPR011989:Armadillo-like helical" CG6177 11-Aug-17 DroID_v2017_08 Drer\cog2 - Cele\cogc-2 Xtro\cog2 Mmus\Cog2 Hsap\COG2 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0084179 fz::wg fz::wg http://flybase.org/reports/FBgn0084179 engineered_fusion_gene - - - fz::wg - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic/first instar larval cuticle FBgn0015528 pff parallel fused fascicles http://flybase.org/reports/FBgn0015528 - gene - - - pff - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085617 CG41327 - http://flybase.org/reports/FBgn0085617 protein_coding_gene - - - CG41327 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266640 CR45147 - http://flybase.org/reports/FBgn0266640 non_protein_coding_gene - - - CR45147 - CR45147 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083023 snoRNA:Psi18S-640d snoRNA:Psi18S-640d http://flybase.org/reports/FBgn0083023 snoRNA_gene - - - "snoRNA:Psi18S-640d, psi18s-640d, CR34578, chr2L:20407188..20407294" - CR34578 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065545 l(2)SH1052 lethal (2) SH1052 http://flybase.org/reports/FBgn0065545 gene - - - l(2)SH1052 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085765 2SrRNA-Psi:CR40677 2S ribosomal RNA pseudogene:CR40677 http://flybase.org/reports/FBgn0085765 pseudogene_attribute - - - "CR40677, 2SrRNA-Psi:CR40677" - CR40677 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084552 E-2c Enhancer on chromosome 2-complementation group c http://flybase.org/reports/FBgn0084552 gene - - - E-2c - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263663 CR43654 - http://flybase.org/reports/FBgn0263663 non_protein_coding_gene - - - CR43654 - CR43654 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038840 CG5621 - http://flybase.org/reports/FBgn0038840 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity with HGNC:4579 ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 regulation of synaptic activity ; GO:0060025 | inferred from sequence or structural similarity with GluRIIA plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with GluRIIA "CG5621, CT17756, anon-WO0138359.5, DKaiRIC, DmelCG5621" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG5621 11-Aug-17 DroID_v2017_08 "Drer\LOC100334689, Drer\grik1a, Drer\grik5, Drer\LOC100331381, Drer\grik4, Drer\si:dkey-183j2.10, Drer\grik1b, Drer\si:ch211-251b21.1" - "Cele\glr-5, Cele\glr-8, Cele\glr-6, Cele\glr-3, Cele\glr-4" "Xtro\grik5, Xtro\grik4, Xtro\grik1" "Mmus\Grik2, Mmus\Grik1, Mmus\Grik5, Mmus\Grik4, Mmus\Grik3" "Hsap\GRIK4, Hsap\GRIK3, Hsap\GRIK2, Hsap\GRIK5, Hsap\GRIK1" viable FBgn0267023 CR45467 - http://flybase.org/reports/FBgn0267023 non_protein_coding_gene - - - CR45467 - CR45467 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011124 l(1)Q86 lethal (1) Q86 http://flybase.org/reports/FBgn0011124 FBgn0010210 gene - - - l(1)Q86 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028371 jbug jitterbug http://flybase.org/reports/FBgn0028371 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype establishment of body hair or bristle planar orientation ; GO:0048104 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with kcc - "CG11605, AAF46896, CG3550, CG13525, CG30092, jbug, Jbug" "IPR001298:Filamin/ABP280 repeat, IPR001589:Actinin-type actin-binding domain, conserved site, IPR001715:Calponin homology domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR017868:Filamin/ABP280 repeat-like" CG30092 11-Aug-17 DroID_v2017_08 "Drer\ehbp1l1a, Drer\flna, Drer\flnca, Drer\zgc:165653, Drer\ehbp1l1b, Drer\ehbp1, Drer\flncb, Drer\flnb" - "Cele\fln-1, Cele\fln-2" "Xtro\flna, Xtro\flnb, Xtro\flnc" "Mmus\Ehbp1, Mmus\Flnb, Mmus\Flna, Mmus\Flnc, Mmus\Ehbp1l1" "Hsap\FLNB, Hsap\FLNC, Hsap\EHBP1L1, Hsap\EHBP1, Hsap\FLNA" "viable,fertile,bang sensitive,planar polarity defective" DRSC04167 K 0.271759414 -0.751950848 -0.585324758 -0.073074472 1.129731535 1.506923133 FBgn0267762 CR46093 - http://flybase.org/reports/FBgn0267762 non_protein_coding_gene - - - CR46093 - CR46093 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015393 hoip hoi-polloi http://flybase.org/reports/FBgn0015393 FBgn0032137 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with HGNC:7819 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000560317 muscle tissue morphogenesis ; GO:0060415 | inferred from mutant phenotype maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with HGNC:7819 maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000560317 positive regulation of translation ; GO:0045727 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement posttranscriptional regulation of gene expression ; GO:0010608 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 nervous system development ; GO:0007399 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000752" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000560317 precatalytic spliceosome ; GO:0071011 | inferred from direct assay box C/D snoRNP complex ; GO:0031428 | inferred from biological aspect of ancestor with PANTHER:PTN000560317 U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000560317 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with HGNC:7819 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000000752 "CG3949, hoip, HOIP, Hoip" "IPR018492:Ribosomal protein L7Ae/L8/Nhp2 family, IPR002415:H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote, IPR004037:Ribosomal protein L7Ae conserved site, IPR004038:Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR029064:50S ribosomal protein L30e-like" CG3949 11-Aug-17 DroID_v2017_08 "Drer\snu13b, Drer\snu13a" Scer\SNU13 Cele\M28.5 "Xtro\rpp38, Xtro\snu13" "Mmus\Nhp2l1, Mmus\Rpp38" "Hsap\RPP38, Hsap\SNU13" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "presumptive embryonic/larval peripheral nervous system,fascicle,embryonic somatic muscle,imaginal disc" DRSC03546 IEK -1.638928189 -0.985587344 -0.394625926 -7.665973904 -2.706352239 -0.931208665 FBgn0001103 gg goggle http://flybase.org/reports/FBgn0001103 - gene - oogenesis ; GO:0048477 | traceable author statement - "l(1)7Fe, fs(1)N83, fs(1)C210, gg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female sterile,male fertile,lethal,recessive,female fertile" "eye,ommatidium,adult head,wing,macrochaeta,trichome,trichome & adult abdomen,head bristle,oocyte" FBgn0263320 CG43401 - http://flybase.org/reports/FBgn0263320 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43401 - CG43401 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003186 qs quicksilver http://flybase.org/reports/FBgn0003186 - gene - - - "su(b), ftd, su(b)[18], l(1)10Fl, qs" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal,male,viable,cold sensitive,partially lethal - majority live,female" "cuticle,mouthpart,denticle belt,cephalopharyngeal skeleton,adult cuticle,male,macrochaeta,puparium" FBgn0263707 CG43659 - http://flybase.org/reports/FBgn0263707 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43659, Dm_2R:85606" - CG43659 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065657 l(2)SH0719 lethal (2) SH0719 http://flybase.org/reports/FBgn0065657 gene - - - "l(2)SH0719, l(2)SH2 0719" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085471 CG34442 - http://flybase.org/reports/FBgn0085471 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34442, CG30070" IPR006631:Protein of unknown function DM4/12 CG34442 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003959 upw upward http://flybase.org/reports/FBgn0003959 - gene - - - upw - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,wing vein" FBgn0040524 CG11052 - http://flybase.org/reports/FBgn0040524 protein_coding_gene acylphosphatase activity ; GO:0003998 | inferred from biological aspect of ancestor with PANTHER:PTN000003030 - - CG11052 "IPR001792:Acylphosphatase-like domain, IPR017968:Acylphosphatase, conserved site, IPR020456:Acylphosphatase" CG11052 11-Aug-17 DroID_v2017_08 "Drer\acyp1, Drer\acyp2" - - "Xtro\acyp2, Xtro\acyp1" "Mmus\Acyp2, Mmus\Acyp1" "Hsap\ACYP1, Hsap\ACYP2" viable FBgn0260486 Ziz Zizimin http://flybase.org/reports/FBgn0260486 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with Zir regulation of Rho protein signal transduction ; GO:0035023 | inferred from sequence or structural similarity with Zir cellular_component ; GO:0005575 | no biological data available "CG42533, BcDNA:RH71439, CG15819, CG6630, Dm ziz, Ziz" "IPR027357:DHR-2 domain, IPR027007:DHR-1 domain, IPR026791:Dedicator of cytokinesis, IPR011989:Armadillo-like helical, IPR010703:Dedicator of cytokinesis, C-terminal, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG42533 11-Aug-17 DroID_v2017_08 "Drer\dock9b, Drer\dock7, Drer\dock11, Drer\dock9a, Drer\zmp:0000001200, Drer\dock10, Drer\dock8" - "Cele\F46H5.4, Cele\F22G12.5" "Xtro\dock8, Xtro\dock6, Xtro\dock10, Xtro\dock7, Xtro\dock11" "Mmus\Dock9, Mmus\Dock11, Mmus\Dock8, Mmus\Dock10, Mmus\Dock6, Mmus\Dock7" "Hsap\DOCK9, Hsap\DOCK6, Hsap\DOCK10, Hsap\DOCK8, Hsap\DOCK11, Hsap\DOCK7" FBgn0029662 CG12206 - http://flybase.org/reports/FBgn0029662 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR002109 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR002109 molecular_function ; GO:0003674 | no biological data available cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR002109 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12206 "IPR002109:Glutaredoxin, IPR012336:Thioredoxin-like fold" CG12206 11-Aug-17 DroID_v2017_08 "Drer\grxcr1, Drer\si:dkey-109l4.6" - "Cele\glrx-5, Cele\glrx-3, Cele\F10D7.3, Cele\Y46E12A.3" - "Mmus\Grxcr1, Mmus\Grxcr2" "Hsap\GRXCR2, Hsap\GLRX3, Hsap\GRXCR1" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267399 CR45761 - http://flybase.org/reports/FBgn0267399 non_protein_coding_gene - - - CR45761 - CR45761 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000716 fnc fine chaetae http://flybase.org/reports/FBgn0000716 - gene - - - fnc - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male sterile,male,eye color defective" "macrochaeta,adult abdomen,wing,pigment cell,adult head" FBgn0011328 l(3)j2B9 lethal (3) j2B9 http://flybase.org/reports/FBgn0011328 - gene - - - l(3)j2B9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261706 CR42742 - http://flybase.org/reports/FBgn0261706 non_protein_coding_gene - - - CR42742 - CR42742 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020014 Egfr::Rat\Neu Egfr::Rat\Neu http://flybase.org/reports/FBgn0020014 - engineered_fusion_gene - - - Egfr::Rat\Neu - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069925 CG41126 - http://flybase.org/reports/FBgn0069925 protein_coding_gene - - - CG41126 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259357 C677 - http://flybase.org/reports/FBgn0259357 gene - - - C677 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0087005 rtp retinophilin http://flybase.org/reports/FBgn0087005 protein_coding_gene - - rhabdomere ; GO:0016028 | inferred from direct assay "CG10233, rtp, 9C4, anon-83ABa, uta, retinophilin, retin" IPR003409:MORN motif CG10233 11-Aug-17 DroID_v2017_08 "Drer\als2a, Drer\rsph10b, Drer\morn4, Drer\jph2, Drer\jph1b, Drer\rsph1, Drer\als2b, Drer\jph3, Drer\si:ch211-146m13.3, Drer\jph1a" - Cele\jph-1 "Xtro\rsph10b, Xtro\morn5, Xtro\rsph1, Xtro\morn4, Xtro\jph2, Xtro\als2, Xtro\als2cl, Xtro\jph1" "Mmus\Morn3, Mmus\Jph4, Mmus\Als2, Mmus\Morn4, Mmus\Rsph1, Mmus\Jph1, Mmus\Jph3, Mmus\Als2cl, Mmus\Morn1, Mmus\Morn5, Mmus\Jph2" "Hsap\MORN1, Hsap\JPH1, Hsap\MORN3, Hsap\RSPH10B2, Hsap\RSPH1, Hsap\JPH3, Hsap\RSPH10B, Hsap\ALS2, Hsap\MORN5, Hsap\JPH2, Hsap\JPH4, Hsap\MORN4, Hsap\ALS2CL" "neurophysiology defective,recessive,viable,body color defective" "rhabdomere,mesothoracic tergum" FBgn0082925 snoRNA:Or-aca1 snoRNA:Or-aca1 http://flybase.org/reports/FBgn0082925 snoRNA_gene - - - "snoRNA:Or-aca1, DmOr_aca1 snoRNA, DmOr_aca1, CR34561, Or-aca1" - CR34561 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069987 BG02100 BG02100 http://flybase.org/reports/FBgn0069987 gene - - - BG02100 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0043489 fs(3)66EFa fs(3)66EFa http://flybase.org/reports/FBgn0043489 gene - - - fs(3)66EFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0001151 gt-3 giant on 3 http://flybase.org/reports/FBgn0001151 - gene - - - "gt-3, gt3" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0060412 l(3)S130008b lethal (3) S130008b http://flybase.org/reports/FBgn0060412 gene - - - "1300/08, l(3)S130008b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019874 anon-92Ee anon-92Ee http://flybase.org/reports/FBgn0019874 - gene - - - anon-92Ee - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010171 sey scratched eyes http://flybase.org/reports/FBgn0010171 - gene - - - sey - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,heat sensitive" FBgn0040001 FASN3 Fatty acid synthase 3 http://flybase.org/reports/FBgn0040001 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR001031 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020843 phosphopantetheine binding ; GO:0031177 | inferred from electronic annotation with InterPro:IPR020806" biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR001031 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR013149 - "DM_7289423, FASN[CG17374], FAS[CG17374], FAS, FASN3, CG17374" "IPR009081:Phosphopantetheine binding ACP domain, IPR013149:Alcohol dehydrogenase, C-terminal, IPR018201:Beta-ketoacyl synthase, active site, IPR011032:GroES-like, IPR014030:Beta-ketoacyl synthase, N-terminal, IPR014031:Beta-ketoacyl synthase, C-terminal, IPR014043:Acyl transferase, IPR016035:Acyl transferase/acyl hydrolase/lysophospholipase, IPR016036:Malonyl-CoA ACP transacylase, ACP-binding, IPR016039:Thiolase-like, IPR016040:NAD(P)-binding domain, IPR032821:Ketoacyl-synthetase, C-terminal extension, IPR020807:Polyketide synthase, dehydratase domain, IPR020843:Polyketide synthase, enoylreductase domain, IPR029058:Alpha/Beta hydrolase fold, IPR001031:Thioesterase, IPR013968:Polyketide synthase, ketoreductase domain, IPR020841:Polyketide synthase, beta-ketoacyl synthase domain, IPR020801:Polyketide synthase, acyl transferase domain, IPR020806:Polyketide synthase, phosphopantetheine-binding domain" CG17374 11-Aug-17 DroID_v2017_08 Drer\fasn Scer\CEM1 "Cele\F32H2.6, Cele\C41A3.1, Cele\fasn-1" Xtro\fasn Mmus\Fasn Hsap\FASN lethal - all die during larval stage embryonic/larval spiracle | larval stage FBgn0035505 Teh2 tipE homolog 2 http://flybase.org/reports/FBgn0035505 protein_coding_gene sodium channel regulator activity ; GO:0017080 | inferred from direct assay regulation of sodium ion transport ; GO:0002028 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG15004, TEH2, Teh2" IPR031578:Na+ channel auxiliary subunit TipE CG15004 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0036856 CG9666 - http://flybase.org/reports/FBgn0036856 protein_coding_gene "methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR002052, InterPro:IPR007848 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002052" methylation ; GO:0032259 | inferred from electronic annotation with InterPro:IPR002052 - "CG9666, Dromel_CG9666_FBtr0074991_mORF" "IPR002052:DNA methylase, N-6 adenine-specific, conserved site, IPR007848:Methyltransferase small domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG9666 11-Aug-17 DroID_v2017_08 Drer\mettl5 - Cele\C38D4.9 Xtro\mettl5 Mmus\Mettl5 Hsap\METTL5 "lethal,viable,fertile,wild-type" FBgn0040294 POSH Plenty of SH3s http://flybase.org/reports/FBgn0040294 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay receptor signaling complex scaffold activity ; GO:0030159 | non-traceable author statement zinc ion binding ; GO:0008270 | inferred from sequence model protein kinase binding ; GO:0019901 | inferred from physical interaction with Tak1 ubiquitin-protein transferase activity ; GO:0004842 | inferred from direct assay germ-band shortening ; GO:0007390 | inferred from mutant phenotype negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | non-traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype response to peptidoglycan ; GO:0032494 | inferred from mutant phenotype regulation of cell-cell adhesion ; GO:0022407 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:17650 "155116_at, DPOSH, posh, CG4909, l(2)k15815, GM09451, BEST:GM09451, POSH, dPOSH" "IPR001452:SH3 domain, IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4909 11-Aug-17 DroID_v2017_08 "Drer\sh3rf1, Drer\sorbs3, Drer\bin2b" Scer\NBP2 "Cele\C36B1.9, Cele\sorb-1, Cele\Y44E3A.4" "Xtro\sh3rf2, Xtro\sh3rf1" "Mmus\Sorbs2, Mmus\Sh3rf2, Mmus\Sh3rf3, Mmus\Sh3rf1" "Hsap\SH3RF2, Hsap\SH3RF1, Hsap\SH3RF3" " embryonic stage | early , wandering third instar larval stage " dorsal mesothoracic disc && ventral thoracic disc

"majority die during embryonic stage,some die during embryonic stage,viable,fertile,melanotic mass phenotype,immune response defective,lethal,recessive,lethal - all die before end of embryonic stage,long lived,planar polarity defective,visible,wild-type,lethal - all die before end of second instar larval stage" "embryonic dorsal epidermis,embryonic head epidermis,germ band,melanotic mass,filamentous actin,embryonic leading edge cell,adherens junction,wing hair,genitalia,tarsal segment,macrochaeta,wing,eye,embryonic dorsal epidermis | dorsal closure stage,adult external thorax" FBgn0000066 Aldox54AF Aldehyde oxidase at 54A-F http://flybase.org/reports/FBgn0000066 - gene - - - "Aldox54AF, Aldox-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020352 anon-34Fa anon-34Fa http://flybase.org/reports/FBgn0020352 - gene - - - "527, anon-34Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065809 l(2)SH0388 lethal (2) SH0388 http://flybase.org/reports/FBgn0065809 gene - - - "l(2)SH0388, l(2)SH2 0388" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039742 CG15528 - http://flybase.org/reports/FBgn0039742 protein_coding_gene "protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR020422 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement" protein dephosphorylation ; GO:0006470 | non-traceable author statement peptidyl-tyrosine dephosphorylation ; GO:0035335 | inferred from biological aspect of ancestor with PANTHER:PTN000017471 cellular_component ; GO:0005575 | no biological data available CG15528 "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like" CG15528 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-121a2.2, Drer\dusp19b, Drer\dusp6, Drer\si:ch211-195b15.8, Drer\dusp8a, Drer\dusp19a, Drer\LOC100150565, Drer\dusp14, Drer\dusp3a, Drer\ssh1a, Drer\si:ch211-203d1.3, Drer\dusp8b, Drer\dupd1, Drer\styx, Drer\dusp5, Drer\si:dkey-175m17.7, Drer\ssh1b, Drer\dusp27, Drer\dusp1, Drer\dusp4, Drer\dusp13a, Drer\dusp2, Drer\si:ch1073-184j22.2, Drer\zgc:153981, Drer\ssh2b, Drer\zgc:153044, Drer\dusp3b, Drer\si:ch211-223p8.8, Drer\dusp28, Drer\ssh2a, Drer\dusp7" "Scer\YVH1, Scer\PPS1, Scer\SDP1, Scer\MSG5" "Cele\F13D11.3, Cele\ZK757.2, Cele\lip-1, Cele\vhp-1, Cele\Y54F10BM.13, Cele\C04F12.8, Cele\F26A3.4" "Xtro\dusp19, Xtro\dusp28, Xtro\dusp6, Xtro\ssh1, Xtro\dusp1, Xtro\dupd1, Xtro\dusp9, Xtro\ssh2, Xtro\styx, Xtro\dusp18, Xtro\dusp26, Xtro\dusp4, Xtro\dusp5" "Mmus\Dusp27, Mmus\Dusp6, Mmus\Dupd1, Mmus\Dusp7, Mmus\Dusp18, Mmus\Dusp19, Mmus\Dusp14, Mmus\Ssh2, Mmus\Dusp28, Mmus\Styx, Mmus\Ssh1, Mmus\Dusp10, Mmus\Dusp8, Mmus\Dusp21, Mmus\Dusp13, Mmus\Dusp4, Mmus\Dusp5, Mmus\Dusp26, Mmus\Dusp2, Mmus\Dusp1, Mmus\Dusp16, Mmus\Ssh3, Mmus\Dusp3, Mmus\Dusp9" "Hsap\DUSP8, Hsap\DUSP4, Hsap\DUSP16, Hsap\SSH3, Hsap\DUSP27, Hsap\DUSP18, Hsap\SSH2, Hsap\DUSP5, Hsap\DUSP6, Hsap\STYX, Hsap\DUSP10, Hsap\SSH1, Hsap\DUSP21, Hsap\DUSP28, Hsap\DUSP2, Hsap\DUSP9, Hsap\DUPD1, Hsap\DUSP1, Hsap\DUSP7, Hsap\DUSP14, Hsap\DUSP3, Hsap\DUSP13, Hsap\DUSP19" viable FBgn0004423 gustD gustatory-defective D http://flybase.org/reports/FBgn0004423 "FBgn0001156, FBgn0001161" gene - - - "gust[x6], gust[x3], gustD" - - 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,heat sensitive,dominant,partially" FBgn0265852 CR44641 - http://flybase.org/reports/FBgn0265852 non_protein_coding_gene - - - CR44641 - CR44641 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002876 mul multiple http://flybase.org/reports/FBgn0002876 FBgn0001681 gene - - - "l(1)ESHS2, l(1)1Cb, mul" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,female sterile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,polyphasic,cell lethal,germline clone" "eye,wing,macrochaeta" FBgn0052128 tRNA:Pro-AGG-1-6 transfer RNA:Proline-AGG 1-6 http://flybase.org/reports/FBgn0052128 tRNA_gene CCU codon-amino acid adaptor activity ; GO:0033421 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033421 cytosol ; GO:0005829 | inferred by curator from GO:0033421 "AE002602.trna17-ProAGG, tRNA:P:AGG:AE002602-b, CR32128, chr3L.trna23-ProAGG, tRNA-Pro-AGG-1-6, tRNA:Pro-AGG-1-6, tRNA:CR32128, CCU" - CR32128 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263216 CG43386 - http://flybase.org/reports/FBgn0263216 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43386, BcDNA:RE65233, CG15251, CG15250" - CG43386 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024236 foi fear-of-intimacy http://flybase.org/reports/FBgn0024236 "FBgn0013623, FBgn0024528, FBgn0026232, FBgn0035908" protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred from direct assay "cell migration ; GO:0016477 | inferred from mutant phenotype gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype pole cell migration ; GO:0007280 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype gonad development ; GO:0008406 | traceable author statement germ cell migration ; GO:0008354 | inferred from mutant phenotype zinc II ion transport ; GO:0006829 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype cellular zinc ion homeostasis ; GO:0006882 | inferred from biological aspect of ancestor with PANTHER:PTN000953562 gonad morphogenesis ; GO:0035262 | inferred from mutant phenotype zinc II ion transmembrane import ; GO:0071578 | inferred from biological aspect of ancestor with PANTHER:PTN000953562" plasma membrane ; GO:0005886 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000953562 integral component of plasma membrane ; GO:0005887 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "foi, kas, dFOI, l(3)j8E8, l(3)neo13, CG6817, FOI, cg6817, dZipFOI, Foi, dZIPfoi" IPR003689:Zinc/iron permease CG6817 11-Aug-17 DroID_v2017_08 "Drer\slc39a4, Drer\slc39a6, Drer\slc39a8, Drer\slc39a10, Drer\slc39a5, Drer\slc39a7" Scer\YKE4 "Cele\Y55F3BL.2, Cele\tag-140, Cele\tag-141" "Xtro\slc39a4, Xtro\slc39a6, Xtro\slc39a7, Xtro\slc39a5, Xtro\slc39a10, Xtro\slc39a8, Xtro\slc39a12, Xtro\slc39a14" "Mmus\Slc39a7, Mmus\Slc39a5, Mmus\Slc39a14, Mmus\Slc39a8, Mmus\Slc39a6, Mmus\Slc39a4, Mmus\Slc39a10, Mmus\Slc39a12" "Hsap\SLC39A10, Hsap\SLC39A4, Hsap\SLC39A12, Hsap\SLC39A8, Hsap\SLC39A5, Hsap\SLC39A7, Hsap\SLC39A14, Hsap\SLC39A6" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,germline clone,rescuable maternal effect,viable,visible,lethal - all die during larval stage" "commissure,eye disc,presumptive embryonic/larval central nervous system,midline glial cell,gonadal sheath proper primordium,fat body/gonad primordium,gonad,precursor,longitudinal connective,eye,anterior,ocellus,head bristle,interface glial cell,peripheral glial cell,somatic clone,glial cell & eye disc | cell non-autonomous | somatic clone,presumptive embryonic/larval muscle system,lateral transverse muscle,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron,embryonic/first instar larval cuticle,germline clone,lateral trunk primordium,presumptive embryonic/larval tracheal system,germline cell,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC10719 IEK -2.094493419 -2.866492547 -1.258620713 -5.373954452 0.821453966 1.939419669 FBgn0000511 du dunkel http://flybase.org/reports/FBgn0000511 - gene - - - du - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,female sterile,dominant,lethal,recessive,cold sensitive,visible,body color defective" wing FBgn0032430 CG6388 - http://flybase.org/reports/FBgn0032430 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002905 tRNA (guanine-N2-)-methyltransferase activity ; GO:0004809 | inferred from biological aspect of ancestor with PANTHER:PTN000066877 tRNA N2-guanine methylation ; GO:0002940 | inferred from biological aspect of ancestor with PANTHER:PTN000066877 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000066877 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000066877 CG6388 "IPR002905:tRNA methyltransferase, Trm1, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG6388 11-Aug-17 DroID_v2017_08 "Drer\trmt1l, Drer\trmt1" Scer\TRM1 Cele\trm-1 Xtro\trmt1 "Mmus\Trmt1, Mmus\Trmt1l" "Hsap\TRMT1, Hsap\TRMT1L" FBgn0038964 Nop56 Nop56 http://flybase.org/reports/FBgn0038964 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000096022 neurogenesis ; GO:0022008 | inferred from mutant phenotype rRNA modification ; GO:0000154 | inferred from biological aspect of ancestor with PANTHER:PTN000096022 cellular response to starvation ; GO:0009267 | inferred from expression pattern small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000096022 box C/D snoRNP complex ; GO:0031428 | inferred from biological aspect of ancestor with PANTHER:PTN000096022 "FBgn0038964, CG13849, Nop56, nop56, Dnop56, DmNop56" "IPR002687:Nop domain, IPR012974:NOP5, N-terminal, IPR012976:NOSIC, IPR011991:Winged helix-turn-helix DNA-binding domain" CG13849 11-Aug-17 DroID_v2017_08 Drer\nop56 "Scer\NOP58, Scer\NOP56" Cele\K07C5.4 "Xtro\nop56, Xtro\nop58" "Mmus\Nop56, Mmus\Nop58" "Hsap\NOP58, Hsap\NOP56" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0005745 l(1)TK237 lethal (1) TK237 http://flybase.org/reports/FBgn0005745 - gene - - - "l237, l(1)TK237" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0264417 FCO-B - http://flybase.org/reports/FBgn0264417 gene - - - FCO-B - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0085480 CG34451 - http://flybase.org/reports/FBgn0085480 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 galactosyltransferase activity ; GO:0008378 | inferred from sequence or structural similarity with CG8708 "protein glycosylation ; GO:0006486 | inferred from sequence or structural similarity with CG8708 O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" cellular_component ; GO:0005575 | no biological data available "CG34451, CG33999" IPR026842:C1GALT1 CG34451 11-Aug-17 DroID_v2017_08 "Drer\c1galt1c1, Drer\si:dkey-202e17.1, Drer\LOC564281, Drer\c1galt1a, Drer\c1galt1b" - "Cele\C16D9.6, Cele\bus-4, Cele\Y38C1AB.1, Cele\Y38C1AB.5, Cele\C38H2.2, Cele\C17A2.3, Cele\E03H4.3, Cele\F37A4.3, Cele\C02H6.1, Cele\T09E11.12, Cele\F56H6.1, Cele\W09D10.5" "Xtro\LOC100496837, Xtro\c1galt1, Xtro\c1galt1c1" "Mmus\C1galt1c1, Mmus\C1galt1" "Hsap\C1GALT1C1L, Hsap\C1GALT1C1, Hsap\C1GALT1" FBgn0266382 CR45024 - http://flybase.org/reports/FBgn0266382 non_protein_coding_gene - - - CR45024 - CR45024 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086388 BG01693 - http://flybase.org/reports/FBgn0086388 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - BG01693 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective,behavior defective,recessive" FBgn0040046 CG12578 - http://flybase.org/reports/FBgn0040046 protein_coding_gene - - - CG12578 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265947 CR44734 - http://flybase.org/reports/FBgn0265947 non_protein_coding_gene - - - CR44734 - CR44734 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011741 Arp6 Actin-related protein 6 http://flybase.org/reports/FBgn0011741 - protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with HGNC:24025 chromatin remodeling ; GO:0006338 | inferred from electronic annotation with InterPro:IPR030054 heterochromatin organization ; GO:0070828 | inferred from sequence or structural similarity with HGNC:24025 nucleus ; GO:0005634 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay "CG11678, ARP13E, Arp4, Arp13E, arp4, ARP(13E), ARP, Acrp, Arp6, Actr13E, dArp6, actr13E" "IPR004000:Actin family, IPR030054:Actin-related protein 6" CG11678 11-Aug-17 DroID_v2017_08 Drer\actr6 Scer\ARP6 Cele\arp-6 Xtro\actr6 Mmus\Actr6 Hsap\ACTR6 embryonic stage -- adult stage "female fertile,viable,female semi-sterile" FBgn0069963 CG41049 - http://flybase.org/reports/FBgn0069963 protein_coding_gene - - - CG41049 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051140 CG31140 - http://flybase.org/reports/FBgn0051140 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 diacylglycerol kinase activity ; GO:0004143 | inferred from sequence or structural similarity with HGNC:2856 diacylglycerol kinase activity ; GO:0004143 | non-traceable author statement metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017438 protein kinase C-activating G-protein coupled receptor signaling pathway ; GO:0007205 | inferred from electronic annotation with InterPro:IPR000756 lateral inhibition ; GO:0046331 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with HGNC:2856 phosphorylation ; GO:0016310 | non-traceable author statement protein kinase C signaling ; GO:0070528 | inferred from sequence or structural similarity with HGNC:2856 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:2856 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:2856 "CG5875, DGKt, CG31452, CG13600, CG31140" "IPR000159:Ras-associating (RA) domain, IPR000756:Diacylglycerol kinase, accessory domain, IPR001206:Diacylglycerol kinase, catalytic domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR020454:Diacylglycerol/phorbol-ester binding, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1, IPR000504:RNA recognition motif domain, IPR029071:Ubiquitin-related domain" CG31140 11-Aug-17 DroID_v2017_08 "Drer\dgkq, Drer\dgkb, Drer\LOC567728, Drer\dgke, Drer\dgkaa" - Cele\dgk-1 "Xtro\dgke, Xtro\dgkb, Xtro\dgka, Xtro\dgkq" "Mmus\Dgkg, Mmus\Dgkq, Mmus\Dgke, Mmus\Dgkb, Mmus\Dgka" "Hsap\DGKG, Hsap\DGKA, Hsap\DGKB, Hsap\DGKQ, Hsap\DGKE" "viable,lethal,partially lethal - majority die,visible" "chaeta,supernumerary" FBgn0037090 Est-Q Esterase Q http://flybase.org/reports/FBgn0037090 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern - "Est-Q, CG7529" "IPR002018:Carboxylesterase, type B, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG7529 11-Aug-17 DroID_v2017_08 "Drer\nlgn2a, Drer\LOC100334697, Drer\cel.1, Drer\nlgn4b, Drer\nlgn4a, Drer\ces2, Drer\si:dkey-30c15.17, Drer\nlgn2b, Drer\ces3, Drer\cell, Drer\nlgn3b, Drer\si:ch211-93f2.1, Drer\nlgn3a, Drer\nlgn1" - "Cele\T28C12.5, Cele\T28C12.4, Cele\K11G9.2, Cele\F07C4.12, Cele\R173.3, Cele\W02B12.4, Cele\F15A8.6, Cele\C52A10.2, Cele\B0238.1, Cele\Y71H2AM.13, Cele\ges-1, Cele\F56C11.6, Cele\C52A10.1, Cele\K11G9.1, Cele\T07H6.1, Cele\K11G9.3, Cele\F13H6.3, Cele\K07C11.4, Cele\B0238.7" "Xtro\LOC100494782, Xtro\ces3, Xtro\nlgn3, Xtro\ces2, Xtro\nlgn2, Xtro\cel, Xtro\nlgn4x" "Mmus\Ces2b, Mmus\Nlgn1, Mmus\Ces5a, Mmus\Ces2a, Mmus\Ces4a, Mmus\Nlgn3, Mmus\Ces2f, Mmus\Ces1f, Mmus\Ces1d, Mmus\Ces2g, Mmus\Ces2h, Mmus\Ces1b, Mmus\Ces3b, Mmus\Cel, Mmus\Ces1h, Mmus\Ces1e, Mmus\Ces3a, Mmus\Nlgn2, Mmus\Ces2c, Mmus\Ces1c, Mmus\Ces1g, Mmus\Ces2e" "Hsap\NLGN3, Hsap\NLGN2, Hsap\NLGN4Y, Hsap\CEL, Hsap\NLGN1, Hsap\CES1, Hsap\CES5A, Hsap\NLGN4X, Hsap\CES4A, Hsap\CES3, Hsap\CES2" viable FBgn0035914 CG6282 - http://flybase.org/reports/FBgn0035914 protein_coding_gene "oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from electronic annotation with InterPro:IPR001104" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR001104 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001104 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001104 CG6282 "IPR001104:3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal, IPR010721:Protein of unknown function DUF1295" CG6282 11-Aug-17 DroID_v2017_08 Drer\si:ch211-210c8.6 - - Xtro\LOC100145110 - - viable FBgn0000495 drg dregs http://flybase.org/reports/FBgn0000495 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "dreg, drg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,embryonic head" FBgn0036289 CG10657 - http://flybase.org/reports/FBgn0036289 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 lateral inhibition ; GO:0046331 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "BEST:LD32330, CG10657" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG10657 11-Aug-17 DroID_v2017_08 "Drer\sec14l7, Drer\rlbp1b, Drer\ttpa, Drer\rlbp1a, Drer\ttpal, Drer\clvs2, Drer\sec14l8" "Scer\SEC14, Scer\SFH5, Scer\YKL091C" - "Xtro\ttpal, Xtro\ttpa, Xtro\mospd2, Xtro\sec14l1, Xtro\sec14l5, Xtro\clvs1, Xtro\clvs2, Xtro\sec14l3, Xtro\rlbp1" "Mmus\Sec14l2, Mmus\Clvs1, Mmus\Sec14l4, Mmus\Rlbp1, Mmus\Ttpal, Mmus\Sec14l5, Mmus\Clvs2, Mmus\Sec14l1, Mmus\Ttpa, Mmus\Sec14l3" "Hsap\SEC14L5, Hsap\TTPAL, Hsap\SEC14L1, Hsap\CLVS2, Hsap\CLVS1, Hsap\TTPA, Hsap\SEC14L3, Hsap\RLBP1, Hsap\SEC14L4, Hsap\SEC14L6, Hsap\SEC14L2" "viable,fertile,visible" "chaeta,trichogen cell" FBgn0067054 R13 R13 http://flybase.org/reports/FBgn0067054 gene - - - R13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,eye color defective,lethal,viable" "eye,pigment cell" FBgn0060589 l(3)S093614 lethal (3) S093614 http://flybase.org/reports/FBgn0060589 gene - - - "0936/14, l(3)S093614" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0086243 grk::CHOp24 - http://flybase.org/reports/FBgn0086243 engineered_fusion_gene - - - "grk::CHOp24, Grk-Emp" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005060 fs(2)OW106 female sterile (2) OW106 http://flybase.org/reports/FBgn0005060 - gene - - - fs(2)OW106 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038326 CG5044 - http://flybase.org/reports/FBgn0038326 protein_coding_gene 3-hydroxyisobutyryl-CoA hydrolase activity ; GO:0003860 | inferred from electronic annotation with InterPro:IPR032259 negative regulation of response to wounding ; GO:1903035 | inferred from mutant phenotype - "CG5044, CT16187, HIBCH" "IPR029045:ClpP/crotonase-like domain, IPR032259:Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type" CG5044 11-Aug-17 DroID_v2017_08 Drer\hibch Scer\EHD3 "Cele\F09F7.4, Cele\ech-7" Xtro\hibch Mmus\Hibch Hsap\HIBCH viable DRSC15705 E 0.151093013 0.74816046 -1.475587046 1.511774336 0.747955593 -0.305713664 FBgn0031976 CG7367 - http://flybase.org/reports/FBgn0031976 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 phagocytosis ; GO:0006909 | inferred from mutant phenotype lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG7367, TL" "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG7367 11-Aug-17 DroID_v2017_08 "Drer\LOC100331214, Drer\lipia, Drer\lipca, Drer\lipib, Drer\lpl, Drer\LOC101884800, Drer\pla1a, Drer\lipg" - - "Xtro\lpl, Xtro\liph, Xtro\lipg" "Mmus\Liph, Mmus\Lipg, Mmus\Pnliprp1, Mmus\Pnlip, Mmus\Lpl, Mmus\Lipc, Mmus\Pnliprp2, Mmus\Lipi, Mmus\Pla1a" "Hsap\LIPI, Hsap\LIPG, Hsap\PNLIPRP2, Hsap\PNLIP, Hsap\LIPH, Hsap\PNLIPRP3, Hsap\PNLIPRP1, Hsap\PLA1A, Hsap\LPL, Hsap\LIPC" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0028154 l(3)S042420 lethal (3) S042420 http://flybase.org/reports/FBgn0028154 gene - - - "0424/20, l(3)S042420" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004989 c(1)a crossover suppressor on 1 http://flybase.org/reports/FBgn0004989 - gene - - - c(1)a - - 11-Aug-17 DroID_v2017_08 - - - - - - meiotic cell cycle defective FBgn0262726 T:SS-nec Signal sequence of nec http://flybase.org/reports/FBgn0262726 engineered_tag - - - "T:SS-nec, T:nec" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040970 CG15492 - http://flybase.org/reports/FBgn0040970 protein_coding_gene - - - CG15492 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053387 5SrRNA:CR33387 5SrRNA:CR33387 http://flybase.org/reports/FBgn0053387 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33387, 5SrRNA:CR33387" - CR33387 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020586 anon-57Ck anon-57Ck http://flybase.org/reports/FBgn0020586 - gene - - - anon-57Ck - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003872 ttx tetrodotoxin-sensitive http://flybase.org/reports/FBgn0003872 - gene - - - ttx - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0031169 CG1494 - http://flybase.org/reports/FBgn0031169 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469" transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 CG1494 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR026082:ABC transporter A, ABCA" CG1494 11-Aug-17 DroID_v2017_08 "Drer\abca3b, Drer\abca2, Drer\abca12, Drer\abch1, Drer\abca1a, Drer\abca5, Drer\abca1b" - "Cele\ced-7, Cele\abt-5, Cele\abt-1" "Xtro\abca8, Xtro\abca3, Xtro\abca4, Xtro\abca2, Xtro\abca9, Xtro\abca1, Xtro\abca10" "Mmus\Abca16, Mmus\Abca5, Mmus\Abca2, Mmus\Abca1, Mmus\Abca4, Mmus\Abca8b, Mmus\Abca14, Mmus\Abca3, Mmus\Abca17, Mmus\Abca6, Mmus\Abca15, Mmus\Abca12, Mmus\Abca7, Mmus\Abca8a, Mmus\Abca9, Mmus\Abca13" "Hsap\ABCA13, Hsap\ABCA3, Hsap\ABCA1, Hsap\ABCA4, Hsap\ABCA7, Hsap\ABCA6, Hsap\ABCA8, Hsap\ABCA10, Hsap\ABCA5, Hsap\ABCA2, Hsap\ABCA9, Hsap\ABCA12" "lethal,recessive,viable" FBgn0085696 CG41566 - http://flybase.org/reports/FBgn0085696 protein_coding_gene - - - CG41566 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019822 eK6 eK6 http://flybase.org/reports/FBgn0019822 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available eK6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261395 Prosalpha3T "Proteasome alpha3 subunit, Testis-specific" http://flybase.org/reports/FBgn0261395 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 molecular_function ; GO:0003674 | no biological data available" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000003367 "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from sequence or structural similarity with SGD:S000003367 male germ cell nucleus ; GO:0001673 | inferred from direct assay" "Prosalpha3T, CG1736, prosalpha3T, Pros20S-alpha3t, alpha3T, :Prosalpha3T" "IPR023332:Proteasome alpha-type subunit, IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR029055:Nucleophile aminohydrolases, N-terminal, IPR034647:Proteasome subunit alpha4" CG1736 11-Aug-17 DroID_v2017_08 Drer\psma4 Scer\PRE9 Cele\pas-3 Xtro\psma4 Mmus\Psma4 Hsap\PSMA4 FBgn0016930 Dyrk2 Dual-specificity tyrosine phosphorylation-regulated kinase 2 http://flybase.org/reports/FBgn0016930 FBgn0027884 protein_coding_gene protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay transferase activity ; GO:0016740 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity ATP binding ; GO:0005524 | inferred from direct assay protein kinase activity ; GO:0004672 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay sensory perception of smell ; GO:0007608 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement olfactory behavior ; GO:0042048 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "smi35A, CG4551, dDYRK2, Dyrk2, DYRK, DYRK2, BG:DS01523.3, Dm2, DmDyrk2" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG4551 11-Aug-17 DroID_v2017_08 "Drer\dyrk2, Drer\si:ch211-160o17.4, Drer\hipk3b, Drer\dyrk1b, Drer\hipk3a, Drer\dyrk1ab, Drer\hipk2, Drer\hipk1a, Drer\dyrk4, Drer\dyrk1aa, Drer\zgc:172180" Scer\YAK1 "Cele\C36B7.2, Cele\mbk-1, Cele\hpk-1, Cele\mbk-2, Cele\C36B7.1" "Xtro\hipk1, Xtro\dyrk3, Xtro\dyrk1a, Xtro\hipk3, Xtro\dyrk2, Xtro\hipk2" "Mmus\Dyrk1b, Mmus\Hipk4, Mmus\Hipk1, Mmus\Dyrk1a, Mmus\Dyrk4, Mmus\Dyrk3, Mmus\Hipk3, Mmus\Dyrk2, Mmus\Hipk2" "Hsap\DYRK1B, Hsap\DYRK1A, Hsap\HIPK4, Hsap\HIPK3, Hsap\DYRK3, Hsap\DYRK2, Hsap\HIPK1, Hsap\HIPK2, Hsap\DYRK4" "viable,smell perception defective,neurophysiology defective,size defective,fertile,visible,behavior defective,recessive,chemosensitive behavior defective" "eye,interommatidial bristle,ectopic,supernumerary,ommatidium | adult stage,retina | pupal stage,tertiary pigment cell,ectopic | pupal stage,secondary pigment cell,cone cell,wing" FBgn0267099 CR45539 - http://flybase.org/reports/FBgn0267099 non_protein_coding_gene - - - CR45539 - CR45539 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011883 tRNA:Ile-AAT-1-5 transfer RNA:Isoleucine-AAT 1-5 http://flybase.org/reports/FBgn0011883 "FBgn0003788, FBgn0050245, FBgn0050521, FBgn0060198" tRNA_gene AUU codon-amino acid adaptor activity ; GO:0033433 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033433 cytosol ; GO:0005829 | inferred by curator from GO:0033433 "CR30521, ile-c, AE002787.trna38-IleAAT, tRNA:I:AAT:AE002787-d, tRNA:ile:49Fc, CR30245, tRNA[Ile], chr2R.trna20-IleAAT, tRNA-Ile[AAU], tRNA-Ile-AAT-1-5, tRNA:Ile-AAT-1-5, tRNA:I:49Fc, AUU" - CR30521 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264941 CR44110 - http://flybase.org/reports/FBgn0264941 non_protein_coding_gene - - - "lincRNA.995, CR44110" - CR44110 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014116 anon-93Fa anon-93Fa http://flybase.org/reports/FBgn0014116 - gene - - - "c159, anon-93Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001475 l(1)9Ee lethal (1) 9Ee http://flybase.org/reports/FBgn0001475 - gene - - - l(1)9Ee - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0017364 l(3)89Br lethal (3) 89Br http://flybase.org/reports/FBgn0017364 - gene - - - "l(3)89Bp, l(3)89Br" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority live" "adult abdomen,wing" FBgn0015884 anon-64Bf anon-64Bf http://flybase.org/reports/FBgn0015884 - gene - - - anon-64Bf - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " antenna

, adult head

, leg

" FBgn0040682 CG14664 - http://flybase.org/reports/FBgn0040682 protein_coding_gene - - - "CG14664, FBgn0040682" - CG14664 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085681 CG41549 - http://flybase.org/reports/FBgn0085681 protein_coding_gene - - - CG41549 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022732 l(2)GPMG-18 lethal (2) GPMG-18 http://flybase.org/reports/FBgn0022732 - gene - - - "GPMG-18, l(2)GPMG-18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034364 CG5493 - http://flybase.org/reports/FBgn0034364 protein_coding_gene "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR010300 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR010300" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010300 - CG5493 "IPR010300:Cysteine dioxygenase type I, IPR011051:RmlC-like cupin domain, IPR014710:RmlC-like jelly roll fold" CG5493 11-Aug-17 DroID_v2017_08 Drer\cdo1 - Cele\cdo-1 Xtro\cdo1 Mmus\Cdo1 Hsap\CDO1 FBgn0011935 tRNA:Asn-GTT-1-7 transfer RNA:Asparagine-GTT 1-7 http://flybase.org/reports/FBgn0011935 "FBgn0003759, FBgn0050318, FBgn0050519, FBgn0060133" tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "AE002769.trna1-AsnGTT, tRNA:N:GTT:AE002769-a, tRNA:asn5:42Ae, CR30318, CR30519, chr2R.trna92-AsnGTT, tRNA-Asn-GTT-1-7, tRNA:Asn-GTT-1-7, tRNA:N5:42Ae, AAC" - CR30519 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020903 Su(osk)2-O26 Suppressor of oskar 2-O26 http://flybase.org/reports/FBgn0020903 - gene - - - "O26, Su(osk)2-O26" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001061 Fs(3)Pal Female sterile (3) Palat http://flybase.org/reports/FBgn0001061 - gene - - - "Fs(3)Palat, Fs(3)Sz19, Fs(3)Pal" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic head,maternal effect" FBgn0002824 ms(2)E3 male sterile (2) E3 http://flybase.org/reports/FBgn0002824 - gene - - - "ms2.3, ms(2)E3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0027317 l(1)G0076 lethal (1) G0076 http://flybase.org/reports/FBgn0027317 - gene - - - l(1)G0076 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022219 l(2)k03501 lethal (2) k03501 http://flybase.org/reports/FBgn0022219 - gene - - - l(2)k03501 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010047 Hdl "Haplo-, diplo-lethal" http://flybase.org/reports/FBgn0010047 - gene - - - Hdl - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061501 l(2)44Fo lethal (2) 44Fo http://flybase.org/reports/FBgn0061501 gene - - - l(2)44Fo - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039935 CG11224 - http://flybase.org/reports/FBgn0039935 protein_coding_gene - - - CG11224 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065342 l(2)SH1833 lethal (2) SH1833 http://flybase.org/reports/FBgn0065342 gene - - - "l(2)SH1833, l(2)SH2 1833" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003137 Ppn Papilin http://flybase.org/reports/FBgn0003137 "FBgn0039586, FBgn0039587, FBgn0053103" protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR010294 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR013273 serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 extracellular matrix structural constituent ; GO:0005201 | inferred from mutant phenotype extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype basement membrane ; GO:0005604 | inferred from direct assay "CG18436, CT41988, CT3186, ppl, CG1540, CG33103, Ppn, ppn" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR008197:WAP-type 'four-disulfide core' domain, IPR010294:ADAM-TS Spacer 1, IPR010909:PLAC, IPR013273:Peptidase M12B, ADAM-TS, IPR013783:Immunoglobulin-like fold, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site, IPR013098:Immunoglobulin I-set, IPR003599:Immunoglobulin subtype" CG33103 11-Aug-17 DroID_v2017_08 "Drer\vwa7, Drer\zmp:0000001289, Drer\spint1b, Drer\spint2, Drer\LOC100333105, Drer\LOC100006752, Drer\si:ch211-286b5.9, Drer\adamts17, Drer\LOC100333244, Drer\zmp:0000000971, Drer\col6a3, Drer\scospondin, Drer\hmcn2, Drer\adamts18, Drer\spegb, Drer\col6a4a, Drer\LOC101884775, Drer\adamts12, Drer\adamts10, Drer\vwa11, Drer\tfpi2, Drer\adamts6, Drer\paplnb, Drer\tfpia, Drer\adamts7, Drer\si:ch211-171h4.5, Drer\LOC568792, Drer\adamts13, Drer\LOC100148735, Drer\LOC101885775, Drer\si:ch211-1f22.3, Drer\spint1a, Drer\si:dkey-117n7.5, Drer\adamtsl7, Drer\si:dkeyp-73b11.8, Drer\sc:d0284, Drer\zgc:172106, Drer\ttnb, Drer\ambp, Drer\wu:fb59d01, Drer\LOC100535144, Drer\vwa10.1, Drer\vwa10.2, Drer\si:ch73-380l3.2, Drer\cd22, Drer\adamtsl5, Drer\paplna, Drer\zgc:171470" - "Cele\Y8A9A.2, Cele\T02G6.11, Cele\mig-6, Cele\Y43F8B.3, Cele\mec-9, Cele\T19D2.1" "Xtro\spint2, Xtro\adamtsl4, Xtro\tfpi2, Xtro\adamts6, Xtro\adamts13, Xtro\adamts16, Xtro\ambp, Xtro\MGC89178, Xtro\adamts17, Xtro\spint1, Xtro\adamts18, Xtro\adamts7, Xtro\hmcn2, Xtro\adamts12, Xtro\papln, Xtro\adamts10" "Mmus\Spint4, Mmus\Adamts7, Mmus\Hmcn1, Mmus\Tfpi, Mmus\Adamts6, Mmus\Spint2, Mmus\Adamtsl5, Mmus\Adamtsl4, Mmus\Spint1, Mmus\Spint5, Mmus\Wfdc6b, Mmus\Ambp, Mmus\Adamts16, Mmus\Adamts12, Mmus\Adamts18, Mmus\Tfpi2, Mmus\Adamts13, Mmus\Wfdc8, Mmus\Adamts17, Mmus\Thsd4, Mmus\Papln, Mmus\Adamts10, Mmus\Adamts19, Mmus\Hmcn2, Mmus\Wfdc6a, Mmus\Eppin, Mmus\Wfikkn1, Mmus\Spint3, Mmus\Ptk7, Mmus\Vwa7, Mmus\Obscn, Mmus\Col6a3" "Hsap\SPINT1, Hsap\WFDC6, Hsap\EPPIN-WFDC6, Hsap\ADAMTS12, Hsap\ADAMTS17, Hsap\WFIKKN1, Hsap\PAPLN, Hsap\COL6A3, Hsap\VWA7, Hsap\ADAMTS18, Hsap\ADAMTS10, Hsap\HMCN1, Hsap\ADAMTSL1, Hsap\ADAMTS16, Hsap\OBSCN, Hsap\SPINT2, Hsap\ADAMTS19, Hsap\WFDC8, Hsap\SPINT4, Hsap\ADAMTSL5, Hsap\THSD4, Hsap\TFPI2, Hsap\ADAMTS7, Hsap\ADAMTS13, Hsap\ADAMTSL4, Hsap\PTK7, Hsap\ADAMTS6, Hsap\TFPI, Hsap\AMBP, Hsap\SPINT3" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval somatic muscle,Malpighian tubule,embryonic/larval tracheal system" FBgn0002910 mw mottler of white http://flybase.org/reports/FBgn0002910 - gene - - - mw - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0032256 RluA-2 RluA-2 http://flybase.org/reports/FBgn0032256 protein_coding_gene "pseudouridine synthase activity ; GO:0009982 | inferred from electronic annotation with InterPro:IPR006145, InterPro:IPR006224, InterPro:IPR006225, InterPro:IPR020103 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002942, InterPro:IPR006145, InterPro:IPR006224, InterPro:IPR006225, InterPro:IPR020103" "pseudouridine synthesis ; GO:0001522 | inferred from electronic annotation with InterPro:IPR006145, InterPro:IPR006224, InterPro:IPR006225, InterPro:IPR020103 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype" - "CG6187, yumo, RluA-2" "IPR006145:Pseudouridine synthase, RsuA/RluB/C/D/E/F, IPR006224:Pseudouridine synthase, RluC/RluD, conserved site, IPR006225:Pseudouridine synthase, RluC/RluD, IPR020103:Pseudouridine synthase, catalytic domain" CG6187 11-Aug-17 DroID_v2017_08 "Drer\rpusd4, Drer\rpusd1, Drer\rpusd2" "Scer\PUS6, Scer\RIB2, Scer\PUS9, Scer\PUS5" Cele\K07E8.7 "Xtro\rpusd2, Xtro\rpusd3, Xtro\rpusd1" "Mmus\Rpusd2, Mmus\Rpusd1, Mmus\Rpusd4, Mmus\Rpusd3" "Hsap\RPUSD3, Hsap\RPUSD2, Hsap\RPUSD1, Hsap\RPUSD4" viable FBgn0261516 Sdic Sperm-specific dynein intermediate chain http://flybase.org/reports/FBgn0261516 protein_coding_gene - microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 Sdic "IPR001680:WD40 repeat, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267055 CR45499 - http://flybase.org/reports/FBgn0267055 pseudogene_attribute - - - CR45499 - CR45499 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267869 CR46157 - http://flybase.org/reports/FBgn0267869 pseudogene_attribute - - - CR46157 - CR46157 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043470 lambdaTry lambdaTry http://flybase.org/reports/FBgn0043470 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP76, lambdaTry, CG12350" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG12350 11-Aug-17 DroID_v2017_08 "Drer\zgc:112038, Drer\si:dkey-21e2.16, Drer\zgc:123295, Drer\si:ch211-165b19.8, Drer\si:dkey-78l4.7, Drer\si:dkey-78l4.1, Drer\si:dkey-78l4.13, Drer\tmprss4b, Drer\zgc:153968, Drer\gzm3, Drer\tmprss4a, Drer\zgc:92590, Drer\si:dkeyp-93a5.2, Drer\prss60.2, Drer\si:dkey-21e2.3, Drer\si:dkey-78l4.6, Drer\prss60.1, Drer\prss60.3, Drer\si:dkey-78l4.2, Drer\try, Drer\zgc:163079" - "Cele\try-1, Cele\svh-1" "Xtro\tmprss4, Xtro\tmprss12" "Mmus\Gzme, Mmus\Prss2, Mmus\Try4, Mmus\Prss3, Mmus\2210010C04Rik, Mmus\Gm5771, Mmus\Prss55, Mmus\Ctsg, Mmus\Tmprss4, Mmus\Prss34, Mmus\Gm10334, Mmus\Try10, Mmus\Prss1" "Hsap\CTSG, Hsap\TMPRSS4, Hsap\PRSS3, Hsap\PRSS1, Hsap\AZU1, Hsap\GZMA, Hsap\ELANE" viable FBgn0024789 Doc\gag Doc element gag http://flybase.org/reports/FBgn0024789 - transposable_element_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - "Doc ORF1, ORF1, Doc\gag" "IPR006579:Pre-C2HC domain, IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034021 CG8180 - http://flybase.org/reports/FBgn0034021 protein_coding_gene - - - CG8180 IPR015943:WD40/YVTN repeat-like-containing domain CG8180 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC07093 I -1.794501295 -0.396226069 -1.124513814 -0.668566947 0.508126096 1.180300476 FBgn0065630 l(2)SH0783 lethal (2) SH0783 http://flybase.org/reports/FBgn0065630 gene - - - "l(2)SH0783, l(2)SH2 0783" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262471 EP1504 - http://flybase.org/reports/FBgn0262471 gene - - - EP1504 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265916 CR44705 - http://flybase.org/reports/FBgn0265916 non_protein_coding_gene - - - "lincRNA.1014, CR44705" - CR44705 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034870 CG13559 - http://flybase.org/reports/FBgn0034870 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of hemocyte proliferation ; GO:0035208 | inferred from genetic interaction with hop cellular_component ; GO:0005575 | no biological data available CG13559 "IPR006629:LPS-induced tumour necrosis factor alpha factor, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13559 11-Aug-17 DroID_v2017_08 "Drer\cdip1, Drer\si:ch211-202h22.7, Drer\si:ch211-202h22.9, Drer\si:ch211-202h22.8, Drer\si:ch211-157c3.4, Drer\si:dkeyp-75b4.8, Drer\litaf, Drer\ubald1a" - "Cele\C08E8.1, Cele\B0348.2, Cele\B0348.1, Cele\Y37D8A.8, Cele\Y37D8A.26, Cele\F36G3.3, Cele\Y22D7AL.15, Cele\Y40H7A.11, Cele\Y37D8A.6, Cele\F16F9.1, Cele\Y87G2A.18" "Xtro\cdip1, Xtro\litaf" "Mmus\Cdip1, Mmus\Litaf" "Hsap\CDIP1, Hsap\LITAF" viable FBgn0069966 CG41041 - http://flybase.org/reports/FBgn0069966 protein_coding_gene - - - CG41041 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051253 CG31253 - http://flybase.org/reports/FBgn0051253 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE50074, CG31253" - CG31253 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028962 AlaRS-m "Alanyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0028962 protein_coding_gene "alanine-tRNA ligase activity ; GO:0004813 | inferred from electronic annotation with InterPro:IPR018162, InterPro:IPR018164, InterPro:IPR018165, InterPro:IPR023033 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012947, InterPro:IPR018162, InterPro:IPR018164, InterPro:IPR018165 alanine-tRNA ligase activity ; GO:0004813 | traceable author statement amino acid binding ; GO:0016597 | inferred from biological aspect of ancestor with PANTHER:PTN000206950 tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000206904" "alanyl-tRNA aminoacylation ; GO:0006419 | inferred from electronic annotation with InterPro:IPR018162, InterPro:IPR018164, InterPro:IPR018165 alanyl-tRNA aminoacylation ; GO:0006419 | traceable author statement tRNA modification ; GO:0006400 | inferred from biological aspect of ancestor with PANTHER:PTN000206950" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002318, InterPro:IPR018162 mitochondrion ; GO:0005739 | traceable author statement" "Dm mt AlaRS, CG4633, AlaS, AlaRS-m, Aats-ala-m" "IPR002318:Alanine-tRNA ligase, class IIc, IPR012947:Threonyl/alanyl tRNA synthetase, SAD, IPR023033:Alanine-tRNA ligase, eukaryota/bacteria, IPR018162:Alanine-tRNA ligase, class IIc, anti-codon-binding domain, IPR018163:Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR018164:Alanyl-tRNA synthetase, class IIc, N-terminal, IPR018165:Alanyl-tRNA synthetase, class IIc, core domain, IPR009000:Translation protein, beta-barrel domain" CG4633 11-Aug-17 DroID_v2017_08 "Drer\aars, Drer\aars2" Scer\ALA1 "Cele\aars-2, Cele\aars-1" Xtro\aars "Mmus\Aars, Mmus\Aars2" "Hsap\AARS, Hsap\AARS2" "viable,visible,planar polarity defective" trichogen cell FBgn0266985 CR45436 - http://flybase.org/reports/FBgn0266985 non_protein_coding_gene - - - CR45436 - CR45436 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000174 ber berrytail http://flybase.org/reports/FBgn0000174 - gene - - - ber - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,viable,male,reduced,poor" "adult abdomen,wing,genitalia,wing hair,wing vein,anterior scutellar bristle,eye" FBgn0040770 CG12939 - http://flybase.org/reports/FBgn0040770 protein_coding_gene - - - "CG18354, CG12939" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060569 l(3)S096101 lethal (3) S096101 http://flybase.org/reports/FBgn0060569 gene - - - "0961/01, l(3)S096101" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004093 l(2)60Da lethal (2) 60Da http://flybase.org/reports/FBgn0004093 - gene - - - l(2)60Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0066351 l(3)99DEd lethal (3) 99DEd http://flybase.org/reports/FBgn0066351 gene - - - l(3)99DEd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004815 fs(2)ltoRN73 female sterile (2) ltoRN73 http://flybase.org/reports/FBgn0004815 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoRN73 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0028631 ksh-16 ksh-16 http://flybase.org/reports/FBgn0028631 gene - - - ksh-16 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260483 CG32714 - http://flybase.org/reports/FBgn0260483 protein_coding_gene - - - "CG1521, BcDNA:RE56803, CG32714" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030831 CG12997 - http://flybase.org/reports/FBgn0030831 protein_coding_gene - - - CG12997 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260051 2L4449 - http://flybase.org/reports/FBgn0260051 gene - - - 2L4449 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0031684 ND-13A NADH dehydrogenase (ubiquinone) 13 kDa A subunit http://flybase.org/reports/FBgn0031684 protein_coding_gene - "respiratory electron transport chain ; GO:0022904 | inferred from sequence or structural similarity with MGI:MGI:107932 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from biological aspect of ancestor with PANTHER:PTN000322556" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000322556 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:107932 "CG8680, NUMM, ND-13A" "IPR016668:NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria, IPR019401:Zinc finger, CHCC-type" CG8680 11-Aug-17 DroID_v2017_08 Drer\ndufs6 - Cele\nduf-6 Xtro\ndufs6 Mmus\Ndufs6 Hsap\NDUFS6 "viable,visible" trichogen cell FBgn0053551 tRNA:Arg-TCG-2-4 transfer RNA:Arginine-TCG 2-4 http://flybase.org/reports/FBgn0053551 tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002708.trna2-ArgTCG, tRNA:R1, tRNA:arg1, CR31444, tRNA:R:TCG:AE002708-b, tRNA:arg85Cb, CR33551, chr3R.trna8-ArgTCG, tRNA-Arg-TCG-2-4, tRNA:Arg-TCG-2-4, tRNA:R:85Cb, CGA" - CR33551 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022334 f4 f4 http://flybase.org/reports/FBgn0022334 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available f4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" "spermatocyte,primary spermatocyte cyst" FBgn0046114 Gclm Glutamate-cysteine ligase modifier subunit http://flybase.org/reports/FBgn0046114 protein_coding_gene glutamate-cysteine ligase catalytic subunit binding ; GO:0035226 | inferred from physical interaction with Gclc enzyme binding ; GO:0019899 | inferred from physical interaction with Gclc enzyme regulator activity ; GO:0030234 | inferred from direct assay glutathione biosynthetic process ; GO:0006750 | inferred from direct assay long-term memory ; GO:0007616 | inferred from mutant phenotype positive regulation of glutamate-cysteine ligase activity ; GO:0035229 | inferred from direct assay behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype glutathione biosynthetic process ; GO:0006750 | inferred from direct assay inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype detoxification of arsenic-containing substance ; GO:0071722 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype glutamate-cysteine ligase complex ; GO:0017109 | inferred from physical interaction with Gclc cytosol ; GO:0005829 | inferred from direct assay "GCLM, DmGCLM, CG4919, box, GCSl, DmGCSl, GCLm, Gcsl, Gclm, gclm, 4919" "IPR023210:NADP-dependent oxidoreductase domain, IPR032963:Glutamate--cysteine ligase regulatory subunit" CG4919 11-Aug-17 DroID_v2017_08 Drer\gclm - Cele\E01A2.1 Xtro\gclm Mmus\Gclm Hsap\GCLM "viable,fertile,memory defective,chemical sensitive" FBgn0000206 boss bride of sevenless http://flybase.org/reports/FBgn0000206 "FBgn0024699, FBgn0024700" protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR017978 glutamate receptor activity ; GO:0008066 | inferred from biological aspect of ancestor with PANTHER:PTN001173581 transmembrane receptor protein tyrosine kinase activator activity ; GO:0030297 | inferred from direct assay transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity receptor binding ; GO:0005102 | non-traceable author statement sevenless binding ; GO:0005118 | inferred from genetic interaction with sev inferred from physical interaction with sev G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity "visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR002956 lipid homeostasis ; GO:0055088 | inferred from mutant phenotype R7 cell differentiation ; GO:0045466 | non-traceable author statement regulation of peptidyl-tyrosine phosphorylation ; GO:0050730 | inferred from direct assay G-protein coupled glutamate receptor signaling pathway ; GO:0007216 | inferred from biological aspect of ancestor with PANTHER:PTN001173581 glucose homeostasis ; GO:0042593 | inferred from mutant phenotype R7 cell development ; GO:0045467 | non-traceable author statement regulation of synaptic transmission, glutamatergic ; GO:0051966 | inferred from biological aspect of ancestor with PANTHER:PTN001173581 response to glucose ; GO:0009749 | inferred from mutant phenotype R8 cell-mediated photoreceptor organization ; GO:0045470 | non-traceable author statement signal transduction ; GO:0007165 | inferred from sequence or structural similarity R7 cell fate commitment ; GO:0007465 | traceable author statement" integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity multivesicular body ; GO:0005771 | inferred from direct assay microvillus membrane ; GO:0031528 | inferred from direct assay "CG8285, X55887, Boss, F, Bos, boss, BOSS" "IPR017978:GPCR family 3, C-terminal, IPR002956:Bride of sevenless protein" CG8285 11-Aug-17 DroID_v2017_08 "Drer\grm3, Drer\gprc5bb, Drer\grm2a, Drer\gprc5c, Drer\grm2b" - "Cele\mgl-3, Cele\mgl-1, Cele\F35H10.10" "Xtro\gprc5c, Xtro\gprc5c, Xtro\gprc5a" "Mmus\Gprc5b, Mmus\Grm2, Mmus\Gprc5a, Mmus\Gprc5d, Mmus\Grm3, Mmus\Gprc5c" "Hsap\GRM2, Hsap\GPRC5A, Hsap\GPRC5D, Hsap\GPRC5C, Hsap\GRM3, Hsap\GPRC5B" " larval stage , adult stage " " imaginal disc

, adult head

" " larval stage , larval stage | third instar , pupal stage ," " ventral thoracic disc

, photoreceptor cell R1 && photoreceptor cell R3 && photoreceptor cell R4 && photoreceptor cell R6 && photoreceptor cell R7

, retina

, ocellus

, morphogenetic furrow | posterior

, eye-antennal disc

, cone cell

, photoreceptor cell R1--8

, morphogenetic furrow | anterior

, photoreceptor cell R8 | presumptive

, mystery cell

" "viable,visible,lethal,recessive,wild-type,small body,stress response defective" "photoreceptor cell R7,ectopic,eye,embryonic/larval oenocyte" DRSC16916 K 0.164044398 0.535942943 0.088379514 0.061172234 0.257120177 -1.643773927 FBgn0065210 l(2)SH2262 lethal (2) SH2262 http://flybase.org/reports/FBgn0065210 gene - - - "l(2)SH2262, l(2)SH2 2262" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060459 l(3)S117708b lethal (3) S117708b http://flybase.org/reports/FBgn0060459 gene - - - "1177/08, l(3)S117708b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062268 Limbr1 Limbr1 http://flybase.org/reports/FBgn0062268 gene - - - "D-Limbr1, Limbr1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032253 LManI Lysosomal alpha-mannosidase I http://flybase.org/reports/FBgn0032253 protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR015341 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from direct assay" protein deglycosylation ; GO:0006517 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 mannose metabolic process ; GO:0006013 | inferred from biological aspect of ancestor with PANTHER:PTN000176395 - "LManI, CG5322" "IPR000602:Glycoside hydrolase family 38, N-terminal domain, IPR011013:Galactose mutarotase-like domain, IPR011682:Glycosyl hydrolase family 38, C-terminal, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR015341:Glycoside hydrolase family 38, central domain, IPR027291:Glycoside hydrolase 38/57, N-terminal domain, IPR028995:Glycoside hydrolase families 57/38, central domain" CG5322 11-Aug-17 DroID_v2017_08 "Drer\man2a1, Drer\man2b1, Drer\man2a2, Drer\man2b2" - Cele\aman-1 "Xtro\man2a1, Xtro\man2a2, Xtro\man2b2, Xtro\man2b1" "Mmus\Man2a1, Mmus\Man2b2, Mmus\Man2b1" "Hsap\MAN2B1, Hsap\MAN2A2, Hsap\MAN2B2, Hsap\MAN2A1" "viable,fertile" FBgn0267347 squ squash http://flybase.org/reports/FBgn0267347 protein_coding_gene - oogenesis ; GO:0048477 | inferred from mutant phenotype gene silencing by RNA ; GO:0031047 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement P granule ; GO:0043186 | inferred from direct assay "squ, CG4711, mat(2)cellHK35, mat(2)cell-A, SQU, atg" - CG4711 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004404 RpS14b Ribosomal protein S14b http://flybase.org/reports/FBgn0004404 "FBgn0002585, FBgn0025283, FBgn0025314, FBgn0025318, FBgn0025321, FBgn0029982" protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001971 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001971 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001971 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "S14, CG1527, RpS14, RPS14B, rpS14B, anon-EST:Posey77, anon-EST:Posey154, anon-EST:Posey131, anon-EST:Posey115, RpS14B, RpS14b, S14b" "IPR018102:Ribosomal S11, conserved site, IPR001971:Ribosomal protein S11" CG1527 11-Aug-17 DroID_v2017_08 "Drer\mrps11, Drer\rps14" "Scer\RPS14B, Scer\RPS14A" "Cele\rps-14, Cele\mrps-11" Xtro\rps14 "Mmus\Mrps11, Mmus\Rps14" "Hsap\MRPS11, Hsap\RPS14" DRSC18711 EK 0.349278098 0.264528208 4.689497469 -2.682965472 1.54500985 2.59026072 FBgn0039623 CG1951 - http://flybase.org/reports/FBgn0039623 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein phosphorylation ; GO:0006468 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available CG1951 "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG1951 11-Aug-17 DroID_v2017_08 Drer\si:ch211-244b2.1 Scer\SCY1 Cele\ZC581.9 Xtro\scyl2 Mmus\Scyl2 Hsap\SCYL2 viable FBgn0030595 CG14406 - http://flybase.org/reports/FBgn0030595 protein_coding_gene - - - CG14406 - CG14406 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0035279 Cpr62Ba Cuticular protein 62Ba http://flybase.org/reports/FBgn0035279 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr62Ba, CG13934, DmelCpr62Ba" IPR000618:Insect cuticle protein CG13934 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0262403 mir-278 mir-278 stem loop http://flybase.org/reports/FBgn0262403 miRNA_gene - negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype - "dme-mir-278, miR-278, mir-278, MIR-278, CR42945, mirvana, Mir-278, CR33589, EP(2)1229, EP2316, EP1229, dme-miR-278" - CR42945 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266991 CR45442 - http://flybase.org/reports/FBgn0266991 non_protein_coding_gene - - - "CR45442, CR45672" - CR45442 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039929 CG11076 - http://flybase.org/reports/FBgn0039929 protein_coding_gene - - - CG11076 - CG11076 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0002862 Mst87F Male-specific RNA 87F http://flybase.org/reports/FBgn0002862 FBgn0046285 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from sequence model spermatogenesis ; GO:0007283 | inferred from expression pattern sperm flagellum ; GO:0036126 | inferred from direct assay "Mst87F, mst87F, bs35f12.y1, Mst, mst(3)gl9, mst(3)87F, mst(3)gl-9, mst-9, BEST:GH23081, CG17956" - CG17956 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030374 CG15734 - http://flybase.org/reports/FBgn0030374 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15734 "IPR008984:SMAD/FHA domain, IPR000253:Forkhead-associated (FHA) domain" CG15734 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037312 CG11999 - http://flybase.org/reports/FBgn0037312 protein_coding_gene dolichyl-phosphate-mannose-protein mannosyltransferase activity ; GO:0004169 | inferred from biological aspect of ancestor with PANTHER:PTN000006098 ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000006098 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000006098 endomembrane system ; GO:0012505 | inferred from direct assay "BEST:LD29996, CG11999, CG-11999" "IPR016093:MIR motif, IPR027005:Glycosyltransferase 39-like" CG11999 11-Aug-17 DroID_v2017_08 "Drer\sdf2, Drer\sdf2l1, Drer\pomt2" "Scer\PMT4, Scer\PMT7, Scer\PMT6, Scer\PMT1, Scer\PMT5, Scer\PMT3, Scer\PMT2" Cele\R12E2.13 "Xtro\sdf2l1, Xtro\sdf2" "Mmus\Pomt2, Mmus\Sdf2l1, Mmus\Sdf2" "Hsap\POMT2, Hsap\SDF2, Hsap\SDF2L1" "viable,fertile" FBgn0004233 l(3)93Bg lethal (3) 93Bg http://flybase.org/reports/FBgn0004233 - gene - - - "rlr5, l(3)93Bg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065899 l(2)SH0203 lethal (2) SH0203 http://flybase.org/reports/FBgn0065899 gene - - - "l(2)SH0203, l(2)SH2 0203" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035132 mthl10 methuselah-like 10 http://flybase.org/reports/FBgn0035132 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "mth2, anon-WO0170980.167, anon-WO0170980.166, CG17061, mthl10, mthl-10" "IPR017981:GPCR, family 2-like, IPR010596:Methuselah, N-terminal domain, IPR000832:GPCR, family 2, secretin-like, IPR023311:Methuselah ectodomain, domain 2" CG17061 11-Aug-17 DroID_v2017_08 "Drer\adgrf11, Drer\si:dkey-100n23.5, Drer\adgrg6" - Cele\lat-2 Xtro\gpr157 "Mmus\Adgre5, Mmus\Adgre1" - FBgn0084654 l(3)S135703 l(3)S135703 http://flybase.org/reports/FBgn0084654 gene - - - l(3)S135703 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051223 CG31223 - http://flybase.org/reports/FBgn0051223 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG15694, CG31223" - CG31223 11-Aug-17 DroID_v2017_08 Drer\znhit2 - Cele\zhit-2 Xtro\znhit2 Mmus\Znhit2 Hsap\ZNHIT2 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0267272 CR45708 - http://flybase.org/reports/FBgn0267272 non_protein_coding_gene - - - CR45708 - CR45708 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085326 CG34297 - http://flybase.org/reports/FBgn0085326 protein_coding_gene protein complex scaffold ; GO:0032947 | inferred from sequence or structural similarity with SGD:S000005533 response to heat ; GO:0009408 | inferred from sequence or structural similarity with SGD:S000005533 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005533 CG34297 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG34297 11-Aug-17 DroID_v2017_08 "Drer\zgc:123010, Drer\tomm34, Drer\ttc4, Drer\tex11, Drer\dyx1c1, Drer\spag1a, Drer\spag1b, Drer\si:dkey-33c12.4, Drer\ttc12" "Scer\SGT2, Scer\TOM70, Scer\SWA2, Scer\TOM71, Scer\CNS1" "Cele\C17G10.2, Cele\C33H5.8" - "Mmus\Dyx1c1, Mmus\Ttc12, Mmus\Ttc4, Mmus\Spag1, Mmus\Tex11, Mmus\Tomm34" "Hsap\TTC4, Hsap\TEX11, Hsap\DYX1C1, Hsap\SPAG1, Hsap\TTC31, Hsap\TOMM34, Hsap\TTC12" FBgn0029518 CG13376 - http://flybase.org/reports/FBgn0029518 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13376 - CG13376 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063918 Max-element\gag-pol gag-pol http://flybase.org/reports/FBgn0063918 transposable_element_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001995" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001995 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - Max-element\gag-pol "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR008737:Peptidase aspartic, putative, IPR008042:Retrotransposon, Pao, IPR001995:Peptidase A2A, retrovirus, catalytic, IPR012337:Ribonuclease H-like domain, IPR005312:Protein of unknown function DUF1759, IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264306 BG01402 - http://flybase.org/reports/FBgn0264306 gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - BG01402 - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive" FBgn0032449 CG17036 - http://flybase.org/reports/FBgn0032449 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000841430 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000841430 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002666 CG17036 "IPR002666:Reduced folate carrier, IPR020846:Major facilitator superfamily domain" CG17036 11-Aug-17 DroID_v2017_08 "Drer\slc19a3b, Drer\slc19a2, Drer\slc19a1, Drer\slc19a3a" - "Cele\folt-2, Cele\folt-1, Cele\folt-3" "Xtro\slc19a1, Xtro\slc19a2" "Mmus\Slc19a1, Mmus\Slc19a2, Mmus\Slc19a3" "Hsap\SLC19A1, Hsap\C2orf83, Hsap\SLC19A3, Hsap\SLC19A2" viable FBgn0267517 5.8SrRNA-Psi:CR45857 5.8S ribosomal RNA pseudogene:CR45857 http://flybase.org/reports/FBgn0267517 pseudogene_attribute - - - "5.8SrRNA-Psi:CR45857, CR45857" - CR45857 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011623 l(2)rot lethal (2) relative of tid http://flybase.org/reports/FBgn0011623 - gene - - - "1(2)rot, l(2)rot" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260039 siren3 siren 3 http://flybase.org/reports/FBgn0260039 gene - - - siren3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0029005 limber limber http://flybase.org/reports/FBgn0029005 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - limber - - 11-Aug-17 DroID_v2017_08 - - - - - - dendrite | dorsal | embryonic stage FBgn0267595 CR45933 - http://flybase.org/reports/FBgn0267595 pseudogene_attribute - - - "CR45933, CG40948" - CR45933 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033266 Socs44A Suppressor of Cytokine Signaling at 44A http://flybase.org/reports/FBgn0033266 protein_coding_gene protein kinase inhibitor activity ; GO:0004860 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from genetic interaction with hop cytokine-mediated signaling pathway ; GO:0019221 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | inferred from genetic interaction with Sos inferred from genetic interaction with Ras85D inferred from genetic interaction with Egfr inferred from genetic interaction with aos negative regulation of protein kinase activity ; GO:0006469 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 "dmSocs44A, SOCS, SOCS44A, socs44A, CG2160, Socs44E, Socs44A, socs42A, Socs44a" "IPR000980:SH2 domain, IPR001496:SOCS box domain" CG2160 11-Aug-17 DroID_v2017_08 "Drer\cishb, Drer\socs5a, Drer\socs6b, Drer\she, Drer\socs2, Drer\socs3b, Drer\socs1b, Drer\pik3r3b, Drer\socs1a, Drer\socs7, Drer\LOC103909359, Drer\socs3a, Drer\cish, Drer\socs4, Drer\socs6, Drer\socs9" - Cele\F39B2.5 "Xtro\socs2, Xtro\socs3, Xtro\socs7, Xtro\socs1, Xtro\socs4, Xtro\socs3, Xtro\socs6, Xtro\cish, Xtro\socs5" "Mmus\Socs1, Mmus\Socs2, Mmus\Socs5, Mmus\Socs7, Mmus\Socs4, Mmus\Socs3, Mmus\Cish, Mmus\Socs6" "Hsap\SOCS2, Hsap\SOCS6, Hsap\CISH, Hsap\SOCS4, Hsap\SOCS7, Hsap\SOCS1, Hsap\SOCS5, Hsap\SOCS3" "visible,viable,fertile" "wing vein L3,wing vein,ectopic" FBgn0028070 l(3)S090302 lethal (3) S090302 http://flybase.org/reports/FBgn0028070 gene - - - "0903/02, l(3)S090302" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065452 l(2)SH1397 lethal (2) SH1397 http://flybase.org/reports/FBgn0065452 gene - - - "l(2)SH1397, l(2)SH2 1397" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085211 RpS28-like Ribosomal protein S28-like http://flybase.org/reports/FBgn0085211 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000005693 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000289 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022627 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with SGD:S000005693 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "RpS28-like, CG34182" "IPR012340:Nucleic acid-binding, OB-fold, IPR000289:Ribosomal protein S28e" CG34182 11-Aug-17 DroID_v2017_08 Drer\rps28 "Scer\RPS28B, Scer\RPS28A" Cele\rps-28 Xtro\rps28p9 Mmus\Rps28 Hsap\RPS28 FBgn0035091 CG3829 - http://flybase.org/reports/FBgn0035091 protein_coding_gene - autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 CG3829 IPR002159:CD36 family CG3829 11-Aug-17 DroID_v2017_08 "Drer\scarb1, Drer\scarb2, Drer\cd36, Drer\LOC564077" - "Cele\scav-2, Cele\scav-4, Cele\scav-3, Cele\scav-6, Cele\scav-1" "Xtro\cd36, Xtro\scarb2, Xtro\scarb1" "Mmus\Scarb1, Mmus\Scarb2, Mmus\Cd36" "Hsap\SCARB2, Hsap\SCARB1, Hsap\CD36" viable FBgn0024615 nate not enough anterior extension http://flybase.org/reports/FBgn0024615 - gene molecular_function ; GO:0003674 | no biological data available Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available nate - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "Bolwig organ,Bolwig nerve" FBgn0085807 CR41590 - http://flybase.org/reports/FBgn0085807 rRNA_gene - - - CR41590 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045851 l(4)102Fa lethal (4) 102Fa http://flybase.org/reports/FBgn0045851 gene - - - l(4)102Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264706 CR43975 - http://flybase.org/reports/FBgn0264706 pseudogene_attribute - - - CR43975 - CR43975 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002790 Mpe Monoplane http://flybase.org/reports/FBgn0002790 - gene - - - "Mpl, Mpe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,semidominant,visible,dominant,viable,poor,flightless,courtship behavior defective" wing FBgn0024202 otb outback http://flybase.org/reports/FBgn0024202 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available otb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051380 CG31380 - http://flybase.org/reports/FBgn0051380 protein_coding_gene - - - "CG4964, CG31380" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG31380 11-Aug-17 DroID_v2017_08 - - "Cele\E02C12.8, Cele\F56A4.5, Cele\Y11D7A.8, Cele\T16G1.6, Cele\Y45G12C.4, Cele\T16G1.5, Cele\C29F7.2, Cele\D1044.1, Cele\F49C12.7, Cele\dhs-27, Cele\E02C12.9, Cele\C18B10.6, Cele\H37A05.2, Cele\nhr-246, Cele\H06H21.8, Cele\E02C12.6, Cele\E02C12.10, Cele\C29F7.1, Cele\F59B1.10, Cele\F59B1.8, Cele\F58B4.5" - - - FBgn0265614 CR44432 - http://flybase.org/reports/FBgn0265614 non_protein_coding_gene - - - CR44432 - CR44432 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039019 HP1c Heterochromatin Protein 1c http://flybase.org/reports/FBgn0039019 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with woc inferred from physical interaction with row methylated histone binding ; GO:0035064 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with row chromatin binding ; GO:0003682 | inferred from direct assay positive regulation of chromatin silencing at telomere ; GO:0031940 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay protein complex ; GO:0043234 | inferred from direct assay euchromatin ; GO:0000791 | colocalizes_with inferred from direct assay "Hp1c, CG6990, HP1c, hp1c, HP1, HP1C" "IPR017984:Chromo domain subgroup, IPR000953:Chromo/chromo shadow domain, IPR008251:Chromo shadow domain, IPR016197:Chromo domain-like, IPR023779:Chromo domain, conserved site, IPR023780:Chromo domain" CG6990 11-Aug-17 DroID_v2017_08 "Drer\cdyl, Drer\cbx1a, Drer\cbx1b, Drer\cbx3a, Drer\cbx3b, Drer\cbx5" - "Cele\hpl-2, Cele\set-31, Cele\hpl-1" "Xtro\cbx1, Xtro\cbx3, Xtro\cbx5" "Mmus\Cbx5, Mmus\Cbx3, Mmus\Cbx1, Mmus\Cdyl" "Hsap\CBX3, Hsap\CBX5, Hsap\CDY2B, Hsap\CBX1, Hsap\CDYL" "viable,fertile" FBgn0060495 l(3)S108116b lethal (3) S108116b http://flybase.org/reports/FBgn0060495 gene - - - "1081/16, l(3)S108116b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000890 fs(1)M88 female sterile (1) M88 http://flybase.org/reports/FBgn0000890 - gene - - - fs(1)M88 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0260746 Ect3 Ectoderm-expressed 3 http://flybase.org/reports/FBgn0260746 protein_coding_gene beta-galactosidase activity ; GO:0004565 | inferred from biological aspect of ancestor with PANTHER:PTN000602923 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001944, InterPro:IPR013781, InterPro:IPR019801 autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern" vacuole ; GO:0005773 | inferred from biological aspect of ancestor with PANTHER:PTN000602923 "Ect3, CG3132, 87A7-9/8, anon-87Ag" "IPR001944:Glycoside hydrolase, family 35, IPR017853:Glycoside hydrolase superfamily, IPR019801:Glycoside hydrolase, family 35, conserved site, IPR008979:Galactose-binding domain-like, IPR026283:Beta-galactosidase 1-like, IPR031330:Glycoside hydrolase 35, catalytic domain, IPR025300:Beta-galactosidase jelly roll domain" CG3132 11-Aug-17 DroID_v2017_08 "Drer\glb1, Drer\si:dkey-224e22.2, Drer\LOC100332851, Drer\slc37a4b, Drer\glb1l" - "Cele\bgal-2, Cele\bgal-1" "Xtro\glb1, Xtro\glb1l" "Mmus\Glb1l3, Mmus\Glb1, Mmus\Gm1110, Mmus\Glb1l, Mmus\Glb1l2" "Hsap\GLB1L, Hsap\GLB1, Hsap\GLB1L3, Hsap\GLB1L2, Hsap\TMPPE" " pupal stage , embryonic stage | cellular blastoderm " " salivary gland

, dorsal ectoderm anlage | restricted

" DRSC15462 I -0.494737721 2.551120895 -0.537365667 0.17019997 0.668161845 -0.216668487 FBgn0042163 CG18843 - http://flybase.org/reports/FBgn0042163 protein_coding_gene - - - CG18843 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045843 RacGAP84C Rac GTPase activating protein at 84C http://flybase.org/reports/FBgn0045843 protein_coding_gene "GTPase activator activity ; GO:0005096 | inferred from direct assay Rho GTPase binding ; GO:0017048 | inferred from physical interaction with Rac1, Cdc42, Cdc42" compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype Rho protein signal transduction ; GO:0007266 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000571279 "rnGAP, GAP84C, rnracGap, RhoGAP-84C8, CG2595, rnRacGAP, rnRacGap, rnprot; racGAP, rnracGAP, rnRac-GAP, P1.7, rnprot1.7, RacGAP84C, RacGAP(84C)" "IPR000198:Rho GTPase-activating protein domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008936:Rho GTPase activation protein" CG2595 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-416j23.1, Drer\racgap1, Drer\chn1" "Scer\RGA2, Scer\RGA1, Scer\ECM25, Scer\RGD1, Scer\BEM3" Cele\cyk-4 Xtro\racgap1 Mmus\Racgap1 Hsap\RACGAP1 "lethal - all die before end of embryonic stage,partially,some die during embryonic stage,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "wing,crossvein,ectopic,wing vein,macrochaeta & thorax,abdomen,dorsal closure embryo,embryonic/first instar larval cuticle,eye,embryonic epidermis,ventral,embryonic leading edge cell,embryonic leading edge cell & actin filamentptc-559.1,ommatidium,retina,eye photoreceptor cell" FBgn0030563 betaNACtes2 "Nascent-associated complex beta-subunit-like, testis 2" http://flybase.org/reports/FBgn0030563 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "betaNACtes2, CG18157" IPR002715:Nascent polypeptide-associated complex NAC domain CG18157 11-Aug-17 DroID_v2017_08 "Drer\btf3, Drer\tab3, Drer\tab2, Drer\btf3l4" "Scer\YML020W, Scer\WWM1, Scer\BTT1, Scer\EGD1" Cele\icd-1 "Xtro\btf3l4, Xtro\btf3" "Mmus\Tab3, Mmus\Tab2, Mmus\Btf3, Mmus\Btf3l4" "Hsap\TAB3, Hsap\BTF3L4, Hsap\BTF3, Hsap\TAB2" FBgn0031618 CG11931 - http://flybase.org/reports/FBgn0031618 protein_coding_gene - - - CG11931 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041588 eIF2D eukaryotic translation initiation factor 2D http://flybase.org/reports/FBgn0041588 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000259347 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC:6583 formation of translation preinitiation complex ; GO:0001731 | inferred from biological aspect of ancestor with PANTHER:PTN000259347 ribosome disassembly ; GO:0032790 | inferred from sequence or structural similarity with HGNC:6583 IRES-dependent translational initiation ; GO:0002192 | inferred from biological aspect of ancestor with PANTHER:PTN000259347 translational initiation ; GO:0006413 | inferred from sequence or structural similarity with HGNC:6583 cytosolic small ribosomal subunit ; GO:0022627 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN000259347 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6583 "CG31426, BcDNA:LD24540, eIF2D, ligatin" "IPR015947:PUA-like domain, IPR001950:SUI1 domain, IPR002478:PUA domain, IPR004521:Uncharacterised domain CHP00451, IPR003121:SWIB/MDM2 domain" CG31426 11-Aug-17 DroID_v2017_08 Drer\eif2d Scer\TMA64 Cele\C25H3.4 Xtro\eif2d Mmus\Eif2d Hsap\EIF2D "viable,fertile" DRSC13916 E 0.074211636 0.271515023 1.572202701 0.301264646 0.184957385 0.209256852 FBgn0013249 E(var)3-14 E(var)3-14 http://flybase.org/reports/FBgn0013249 - gene - - - "E-var(3)14, E(var)3-14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0010127 l(1)adl2 lethal (1) adult http://flybase.org/reports/FBgn0010127 - gene - - - "adl-2, l(1)adl-2, addB, l(1)adl2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "hypoactive,lethal,heat sensitive,some die during immature adult stage,recessive" FBgn0260464 CG9288 - http://flybase.org/reports/FBgn0260464 protein_coding_gene - - - "CG9288, Dromel_CG9288_FBtr0082829_pyruvatekinasedomain_mORF" "IPR011053:Single hybrid motif, IPR033753:Glycine cleavage system H-protein/Simiate" CG9288 11-Aug-17 DroID_v2017_08 Drer\fam206a - Cele\F54F2.7 Xtro\fam206a Mmus\Fam206a Hsap\FAM206A "viable,fertile" FBgn0030439 CG12716 - http://flybase.org/reports/FBgn0030439 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern chorion ; GO:0042600 | inferred by curator from GO:0007304 CG12716 IPR002350:Kazal domain CG12716 11-Aug-17 DroID_v2017_08 "Drer\reck, Drer\tmeff1b, Drer\tmeff1a, Drer\tmeff2b" - Cele\F29G6.1 - "Mmus\Spink2, Mmus\Spink7, Mmus\Fstl3, Mmus\Spink12, Mmus\Spink13, Mmus\Spink5, Mmus\Spink4, Mmus\Spink6, Mmus\Reck, Mmus\Spink1" "Hsap\SPINK6, Hsap\FSTL3, Hsap\SPINK13, Hsap\SPINK4, Hsap\SPINK7, Hsap\SPINK1, Hsap\RECK, Hsap\SPINK5" viable FBgn0017460 TfIIIC Transcription factor IIIC http://flybase.org/reports/FBgn0017460 - gene - transcription from RNA polymerase III promoter ; GO:0006383 | traceable author statement - "TFIIIC, IIIC, TfIIIC" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037622 CG8202 - http://flybase.org/reports/FBgn0037622 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8202 "IPR011989:Armadillo-like helical, IPR029705:UPF0505 family" CG8202 11-Aug-17 DroID_v2017_08 Drer\zgc:163107 - Cele\F26G1.1 Xtro\c16orf62 Mmus\9030624J02Rik Hsap\C16orf62 viable FBgn0053252 CG33252 - http://flybase.org/reports/FBgn0053252 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33252 - CG33252 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069307 X-63-3 X-63-3 http://flybase.org/reports/FBgn0069307 gene molecular_function ; GO:0003674 | no biological data available segment polarity determination ; GO:0007367 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-63-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal phenotype,germline clone,maternal effect,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,denticle belt" FBgn0045442 mthl12 methuselah-like 12 http://flybase.org/reports/FBgn0045442 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "CG32853, mthl12, Mthl12" "IPR017981:GPCR, family 2-like, IPR010596:Methuselah, N-terminal domain, IPR022343:GCR1-cAMP receptor, IPR023311:Methuselah ectodomain, domain 2" CG32853 11-Aug-17 DroID_v2017_08 "Drer\adgrg6, Drer\adgrf11" - Cele\lat-2 Xtro\gpr157 Mmus\Adgre1 - viable FBgn0060804 l(3)S056906 lethal (3) S056906 http://flybase.org/reports/FBgn0060804 gene - - - "0569/06, l(3)S056906" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0259871 Su(Ste):CR42440 Su(Ste):CR42440 http://flybase.org/reports/FBgn0259871 non_protein_coding_gene - - - "Su(Ste):CR42440, CR42440" - CR42440 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015019 CCT3 Chaperonin containing TCP1 subunit 3 http://flybase.org/reports/FBgn0015019 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012719 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" "protein folding ; GO:0006457 | inferred from sequence or structural similarity 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000143681 chaperonin-containing T-complex ; GO:0005832 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay "Cctg, CG8977, Y, geneY, Cctgamma, cct-gamma, cctgamma, Tcp-1-gamma, Cct-gamma, TCPG_DROME, Cct3, Tcp-1gamma, Tcp1-gamma, vine, cctg, CCTgamma, CCT3, TCP1-gamma" "IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012719:T-complex protein 1, gamma subunit, IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG8977 11-Aug-17 DroID_v2017_08 Drer\cct3 Scer\CCT3 Cele\cct-3 Xtro\cct3 Mmus\Cct3 Hsap\CCT3 lethal "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0261847 CG42779 - http://flybase.org/reports/FBgn0261847 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42779 - CG42779 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004203 l(3)84Ea lethal (3) 84Ea http://flybase.org/reports/FBgn0004203 - gene - - - l(3)84Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265162 CR44231 - http://flybase.org/reports/FBgn0265162 non_protein_coding_gene - - - CR44231 - CR44231 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002734 E(spl)mdelta-HLH "Enhancer of split mdelta, helix-loop-helix" http://flybase.org/reports/FBgn0002734 - protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" R1/R6 cell differentiation ; GO:0048052 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype - "CG8328, mdelta, E(spl)mdelta, mdelta0.5, E(Spl)-HLH-mdelta, E(spl)mC, mC, HLHMD, E(Spl) HLH-m delta, E(spl)-mdelta, E(spl)Mdelta, E(spl) mdelta, E(spl)delta, HLH-mdelta, HLHmdelta, HLHmC, bHLHc14, E(spl)mdelta-HLH, md, HLHMdelta, Mdelta" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8328 11-Aug-17 DroID_v2017_08 "Drer\her13, Drer\her9, Drer\hes2.1, Drer\bhlhe41, Drer\LOC100149863, Drer\her11, Drer\her15.2, Drer\her12, Drer\her4.3, Drer\her8.2, Drer\hes2.2, Drer\her4.4, Drer\hey1, Drer\her15.1, Drer\her1, Drer\hey2, Drer\her7, Drer\her8a, Drer\her6, Drer\her5, Drer\helt, Drer\heyl, Drer\her3, Drer\her4.2, Drer\hes6, Drer\her2, Drer\bhlhe40" Scer\PHO4 "Cele\hlh-25, Cele\lin-22, Cele\hlh-27" "Xtro\bhlhe41, Xtro\hes6.1, Xtro\hes6.2, Xtro\hes4, Xtro\hes2, Xtro\hes1, Xtro\hey1, Xtro\hey2, Xtro\hes7.1, Xtro\bhlhe40, Xtro\hes7.2" "Mmus\Helt, Mmus\Heyl, Mmus\Hes5, Mmus\Hey2, Mmus\Hes2, Mmus\Hes1, Mmus\Hey1, Mmus\Hes7, Mmus\Hes6, Mmus\Bhlhe41, Mmus\Bhlhe40, Mmus\Hes3" "Hsap\HEYL, Hsap\HES4, Hsap\BHLHE40, Hsap\HEY2, Hsap\HES3, Hsap\HES6, Hsap\HES2, Hsap\HES1, Hsap\BHLHE41, Hsap\HES5, Hsap\HELT, Hsap\HES7, Hsap\HEY1" "visible,lethal - all die before end of P-stage,some die during pharate adult stage,viable" "scutellar bristle,wing vein,wing margin bristle,scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutum & macrochaetah-1J3,macrochaeta,photoreceptor cell R8,eye,microchaeta,adult thorax,ommatidium,photoreceptor cell R7,ectopic,photoreceptor cell R1,photoreceptor cell R6,trichogen cell" FBgn0015834 eIF3i eukaryotic translation initiation factor 3 subunit i http://flybase.org/reports/FBgn0015834 - protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR027525 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translational initiation ; GO:0006413 | inferred from sequence or structural similarity eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from electronic annotation with InterPro:IPR027525 microtubule associated complex ; GO:0005875 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity "eIF3-S2, CG8882, DmTRIP, Trip1, eIF-3beta, eIF3i, TRIP1" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR027525:Eukaryotic translation initiation factor 3 subunit I" CG8882 11-Aug-17 DroID_v2017_08 Drer\eif3i Scer\TIF34 Cele\eif-3.I Xtro\eif3i Mmus\Eif3i Hsap\EIF3I lethal DRSC03464 IE 0.086258597 -2.043262567 0.215513546 -3.301775125 -0.077499966 0.725667591 FBgn0034263 CG10934 - http://flybase.org/reports/FBgn0034263 protein_coding_gene - - - "anon-WO0140519.130, CG10934" - CG10934 11-Aug-17 DroID_v2017_08 - - - - - - DRSC06017 K -0.235655961 0.242543662 -1.297166757 0.084469433 -0.323908376 -4.129704198 FBgn0266400 CR45040 - http://flybase.org/reports/FBgn0266400 non_protein_coding_gene - - - "CR45040, lincRNA.856" - CR45040 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264791 CR44021 - http://flybase.org/reports/FBgn0264791 non_protein_coding_gene - - - CR44021 - CR44021 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084018 CG41456 - http://flybase.org/reports/FBgn0084018 protein_coding_gene - - - CG41456 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005481 l(1)ts1233 lethal (1) ts1233 http://flybase.org/reports/FBgn0005481 - gene - - - l(1)ts1233 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0036557 mRpS31 mitochondrial ribosomal protein S31 http://flybase.org/reports/FBgn0036557 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q92665 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q92665 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q92665 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "RpS31, MRP-S31, CG5904, mRpS31" IPR026299:Mitochondrial 28S ribosomal protein S31 CG5904 11-Aug-17 DroID_v2017_08 Drer\mrps31 - Cele\mrps-31 Xtro\mrps31 Mmus\Mrps31 Hsap\MRPS31 "viable,visible" trichogen cell FBgn0085767 CR40685 - http://flybase.org/reports/FBgn0085767 rRNA_gene - - - CR40685 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263503 CR43492 - http://flybase.org/reports/FBgn0263503 non_protein_coding_gene - - - CR43492 - CR43492 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032284 CG7294 - http://flybase.org/reports/FBgn0032284 protein_coding_gene - - - "BcDNA:RE28280, CG7294" - CG7294 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0061086 l(3)S012124 lethal (3) S012124 http://flybase.org/reports/FBgn0061086 gene - - - "0121/24, l(3)S012124" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0052819 CG32819 - http://flybase.org/reports/FBgn0052819 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with SGD_LOCUS:SPC110; SGD:S000002764 microtubule nucleation ; GO:0007020 | inferred from sequence or structural similarity with SGD_LOCUS:SPC110; SGD:S000002764 flagellated sperm motility ; GO:0030317 | inferred from sequence or structural similarity with MGD:Tekt3; MGI:MGI:1918312 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGD:Tekt3; MGI:MGI:1918312 CG32819 IPR000435:Tektin CG32819 11-Aug-17 DroID_v2017_08 "Drer\tekt2, Drer\tekt3, Drer\tekt1, Drer\tekt4" Scer\SPC110 Cele\R02E12.4 "Xtro\tekt4, Xtro\tekt3, Xtro\tekt2, Xtro\tekt1" "Mmus\Tekt4, Mmus\Tekt1, Mmus\Tekt5, Mmus\Tekt2, Mmus\Tekt3" "Hsap\TEKT5, Hsap\TEKT4, Hsap\TEKT1, Hsap\TEKT3, Hsap\TEKT2" FBgn0013439 dsx::ftz dsx::ftz http://flybase.org/reports/FBgn0013439 - engineered_fusion_gene - - - dsx::ftz - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005152 l(2)G93 lethal (2) G93 http://flybase.org/reports/FBgn0005152 - gene - - - l(2)G93 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020924 H-39 H-39 http://flybase.org/reports/FBgn0020924 - gene - - - H-39 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038183 CG9286 - http://flybase.org/reports/FBgn0038183 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from sequence or structural similarity with HGNC:978 regulation of protein kinase activity ; GO:0045859 | inferred from sequence or structural similarity with HGNC:978 cellular_component ; GO:0005575 | no biological data available CG9286 IPR025602:BCP1 family CG9286 11-Aug-17 DroID_v2017_08 Drer\bccip Scer\BCP1 Cele\ZK1127.4 Xtro\bccip Mmus\Bccip Hsap\BCCIP "viable,fertile" FBgn0002950 nofA no object fixation A http://flybase.org/reports/FBgn0002950 - gene - - - "S100, nofA" - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective eye FBgn0085328 CG34299 - http://flybase.org/reports/FBgn0085328 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34299 - CG34299 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035043 CG4781 - http://flybase.org/reports/FBgn0035043 protein_coding_gene - axonogenesis ; GO:0007409 | inferred from biological aspect of ancestor with PANTHER:PTN000689992 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 proteinaceous extracellular matrix ; GO:0005578 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 "CT15357, CG4781, 4781" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG4781 11-Aug-17 DroID_v2017_08 Drer\si:dkey-182i3.11 - "Cele\lron-11, Cele\lron-7" - - - viable DRSC04488 I 1.59029473 1.21024675 0.731745296 0.384197866 0.644260174 0.659019684 FBgn0038549 CG17802 - http://flybase.org/reports/FBgn0038549 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG17802 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR003604:Matrin/U1-C-like, C2H2-type zinc finger" CG17802 11-Aug-17 DroID_v2017_08 "Drer\bcl6ab, Drer\znf408" Scer\AZF1 "Cele\klf-3, Cele\blmp-1, Cele\M03D4.4, Cele\zfp-2, Cele\ztf-23" Xtro\zbtb26 "Mmus\Zfp369, Mmus\Zfp518b, Mmus\Zscan5b, Mmus\Zfp445, Mmus\Rbak, Mmus\Zfp110, Mmus\Zfp24" "Hsap\ZNF773, Hsap\ZNF550, Hsap\ZNF557, Hsap\ZNF844, Hsap\ZNF3, Hsap\ZNF124, Hsap\ZNF662, Hsap\ZSCAN5B, Hsap\ZKSCAN8, Hsap\ZNF8, Hsap\ZKSCAN3, Hsap\ZNF449, Hsap\ZSCAN26, Hsap\ZNF383, Hsap\ZSCAN21, Hsap\ZNF500, Hsap\ZSCAN10, Hsap\ZNF24, Hsap\ZNF396, Hsap\ZNF701, Hsap\ZNF669, Hsap\ZSCAN20, Hsap\ZNF483, Hsap\ZNF354C, Hsap\ZSCAN25, Hsap\ZSCAN30, Hsap\ZNF444, Hsap\GZF1, Hsap\ZNF565, Hsap\ZNF263, Hsap\ZNF397, Hsap\ZNF285, Hsap\ZNF10, Hsap\ZNF649, Hsap\ZNF460, Hsap\ZNF789, Hsap\ZNF554, Hsap\ZFP92, Hsap\ZNF19, Hsap\MZF1, Hsap\ZSCAN23, Hsap\ZNF75D, Hsap\ZNF829, Hsap\ZNF154, Hsap\ZNF205, Hsap\ZIM3, Hsap\ZNF518B, Hsap\ZKSCAN4, Hsap\ZNF735, Hsap\ZKSCAN7, Hsap\ZNF641, Hsap\ZNF213, Hsap\ZNF621, Hsap\ZNF684, Hsap\ZNF574, Hsap\ZNF232, Hsap\ZNF584, Hsap\ZNF496, Hsap\ZNF202, Hsap\ZNF506, Hsap\ZNF286A, Hsap\ZNF566, Hsap\ZNF582, Hsap\ZNF620, Hsap\ZNF350, Hsap\ZNF302, Hsap\ZNF577, Hsap\ZSCAN31, Hsap\ZNF169, Hsap\ZNF197, Hsap\ZNF485, Hsap\ZKSCAN1, Hsap\ZNF736, Hsap\ZFP69B, Hsap\ZNF562, Hsap\ZKSCAN5, Hsap\ZSCAN16, Hsap\ZNF281, Hsap\ZNF806, Hsap\ZNF274, Hsap\ZNF547, Hsap\ZNF2, Hsap\ZNF101, Hsap\ZNF18, Hsap\ZFP69, Hsap\ZNF514, Hsap\ZSCAN22, Hsap\ZNF517, Hsap\ZSCAN12, Hsap\ZSCAN1, Hsap\ZNF140" "partially lethal - majority die,some die during pupal stage" FBgn0264649 liquid-filled liquid filled http://flybase.org/reports/FBgn0264649 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - liquid-filled - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0263750 CG43675 - http://flybase.org/reports/FBgn0263750 protein_coding_gene - - - "CG43675, anon-85Da, CG16750, CG16751, CG33936, CG33188, CG3393, CG33187, CG33937, BcDNA:RE70963, drn" - CG43675 11-Aug-17 DroID_v2017_08 "Drer\zfand5a, Drer\zfand5b, Drer\zfand4, Drer\zfand6, Drer\zgc:77486" - Cele\F22D6.2 "Xtro\zfand6, Xtro\zfand4, Xtro\zfand5" "Mmus\Zfand5, Mmus\Zfand6, Mmus\Zfand4" "Hsap\ZFAND6, Hsap\ZFAND5" FBgn0043458 CG12084 - http://flybase.org/reports/FBgn0043458 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN000985199 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with UniProtKB:Q7Z7L7 regulation of ubiquitin-protein transferase activity ; GO:0051438 | inferred from biological aspect of ancestor with PANTHER:PTN000985199 regulation of ubiquitin-protein transferase activity ; GO:0051438 | inferred from sequence or structural similarity with UniProtKB:Q7Z7L7 Cul2-RING ubiquitin ligase complex ; GO:0031462 | inferred from biological aspect of ancestor with PANTHER:PTN000985199 Cul2-RING ubiquitin ligase complex ; GO:0031462 | inferred from sequence or structural similarity with UniProtKB:Q7Z7L7 "LD02105, BEST:LD02105, CG12084" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR032675:Leucine-rich repeat domain, L domain-like, IPR000225:Armadillo" CG12084 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-82l19.1, Drer\zyg11, Drer\zer1" - Cele\zer-1 "Xtro\zer1, Xtro\zyg11b" "Mmus\Zer1, Mmus\Zyg11b, Mmus\Zyg11a" "Hsap\ZYG11A, Hsap\ZYG11B, Hsap\ZER1" "visible,viable" "dorsocentral bristle,scutellar bristle,trichogen cell,thecogen cell,tormogen cell,eye" FBgn0017630 Eig19C Eig19C http://flybase.org/reports/FBgn0017630 - gene - - - "Eig19, Eig19C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044096 E(rst)D160 E(rst)D160 http://flybase.org/reports/FBgn0044096 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D160, E(rst)D160" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026267 ap::Lim3 ap::Lim3 http://flybase.org/reports/FBgn0026267 - engineered_fusion_gene - - - ap::Lim3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011367 l(3)j4D1 lethal (3) j4D1 http://flybase.org/reports/FBgn0011367 FBgn0011384 gene - - - "l(3)j5D1, l(3)j4D1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034974 CG16786 - http://flybase.org/reports/FBgn0034974 protein_coding_gene - - - CG16786 - CG16786 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032258 CG7456 - http://flybase.org/reports/FBgn0032258 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "Golgi organization ; GO:0007030 | inferred from sequence or structural similarity with UniProtKB:Q9H9E3 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000613642 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000006309 Golgi vesicle prefusion complex stabilization ; GO:0048213 | inferred from biological aspect of ancestor with PANTHER:PTN000613642 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000613642 retrograde transport, vesicle recycling within Golgi ; GO:0000301 | inferred from biological aspect of ancestor with PANTHER:PTN000613642" Golgi transport complex ; GO:0017119 | inferred from direct assay Golgi transport complex ; GO:0017119 | inferred from sequence or structural similarity with HGNC:18620 "CG7456, Cog4" "IPR013167:Conserved oligomeric Golgi complex, subunit 4" CG7456 11-Aug-17 DroID_v2017_08 Drer\cog4 Scer\COG4 Cele\cogc-4 Xtro\cog4 Mmus\Cog4 Hsap\COG4 FBgn0060697 l(3)S072517b lethal (3) S072517b http://flybase.org/reports/FBgn0060697 gene - - - "0725/17, l(3)S072517b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086323 JV47 - http://flybase.org/reports/FBgn0086323 gene - - - JV47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0020870 anon-Q212 anon-Q212 http://flybase.org/reports/FBgn0020870 - gene - - - "2-Q212, anon-Q212" - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0027096 A45 A45 http://flybase.org/reports/FBgn0027096 - gene - - - A45 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028060 l(3)S093411 lethal (3) S093411 http://flybase.org/reports/FBgn0028060 gene - - - "0934/11, l(3)S093411" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011720 TA7-1a TA7-1a http://flybase.org/reports/FBgn0011720 - gene - - - TA7-1a - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021584 DdbP3 Damage-specific DNA-binding protein 3 http://flybase.org/reports/FBgn0021584 - gene damaged DNA binding ; GO:0003684 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "D-DDB P3, DdbP3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014299 l(3)64Bj lethal (3) 64Bj http://flybase.org/reports/FBgn0014299 - gene - - - l(3)64Bj - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267545 CR45885 - http://flybase.org/reports/FBgn0267545 non_protein_coding_gene - - - CR45885 - CR45885 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267539 CR45879 - http://flybase.org/reports/FBgn0267539 non_protein_coding_gene - - - CR45879 - CR45879 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259367 EP-439 - http://flybase.org/reports/FBgn0259367 gene - - - EP-439 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0052548 CG32548 - http://flybase.org/reports/FBgn0052548 protein_coding_gene - - - "CG6306, CG15051, anon-WO0140519.88, CG32548" IPR015943:WD40/YVTN repeat-like-containing domain CG32548 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19627 IK 0.362626637 1.586092267 1.146392202 0.373259188 2.196985735 0.224353377 FBgn0001931 l(2)25Ed lethal (2) 25Ed http://flybase.org/reports/FBgn0001931 - gene - - - "jf28, l(2)gdh-8, l(2)jf28, l(2)gdh8, l(2)25Ed" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034471 Obp56e Odorant-binding protein 56e http://flybase.org/reports/FBgn0034471 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "56e, CG8462, Obp56e, DmelObp56e, obp56e" IPR006170:Pheromone/general odorant binding protein CG8462 11-Aug-17 DroID_v2017_08 - - Cele\T28A11.16 - - - "behavior defective,viable" FBgn0005385 rsd raised http://flybase.org/reports/FBgn0005385 - gene - actin modification ; GO:0030047 | inferred from mutant phenotype - "mod, rsd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,dominant,cold sensitive,visible,recessive,courtship behavior defective,male,flight defective" wing FBgn0052813 CG32813 - http://flybase.org/reports/FBgn0052813 protein_coding_gene - - - "CG14771, CG11446, anon-WO0153538.75, CG32813" IPR028002:Myb/SANT-like DNA-binding domain CG32813 11-Aug-17 DroID_v2017_08 - - - - - Hsap\RAD54B "viable,fertile" "embryonic/larval hemocyte | third instar larval stage,lamellocyte | third instar larval stage" FBgn0025621 CG16989 - http://flybase.org/reports/FBgn0025621 - protein_coding_gene - - - "EG:34F3.4, CG16989" "IPR025283:Domain of unknown function DUF4042, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG16989 11-Aug-17 DroID_v2017_08 Drer\heatr6 - - Xtro\heatr6 Mmus\Heatr6 Hsap\HEATR6 viable FBgn0052657 CR32657 - http://flybase.org/reports/FBgn0052657 non_protein_coding_gene - - - "BEST:GH20356, CR32657" - CR32657 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031530 pgant2 polypeptide GalNAc transferase 2 http://flybase.org/reports/FBgn0031530 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement "CG3254, pgant2, PGANT2" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG3254 11-Aug-17 DroID_v2017_08 "Drer\galnt16, Drer\galnt14, Drer\galnt6, Drer\galnt7, Drer\galnt13, Drer\LOC103910015, Drer\galnt1, Drer\poc1bl, Drer\galnt12, Drer\si:ch211-15e22.3, Drer\galnt2" - "Cele\gly-9, Cele\gly-10, Cele\gly-3, Cele\gly-4, Cele\gly-11, Cele\gly-7" "Xtro\galnt16, Xtro\galnt7, Xtro\galnt6.1, Xtro\galnt1, Xtro\galnt12, Xtro\galnt10, Xtro\galnt14, Xtro\galnt2, Xtro\galnt13, Xtro\galnt4" "Mmus\Galnt12, Mmus\Galnt10, Mmus\Galnt7, Mmus\Galnt5, Mmus\Galnt13, Mmus\Galnt6, Mmus\Galnt3, Mmus\Galnt11, Mmus\Galntl6, Mmus\Galntl5, Mmus\Galnt2, Mmus\Galnt16, Mmus\Galnt14, Mmus\Galnt4" "Hsap\GALNT4, Hsap\GALNT2, Hsap\GALNTL5, Hsap\GALNT13, Hsap\GALNT1, Hsap\GALNT6, Hsap\GALNT11, Hsap\GALNT5, Hsap\POC1B-GALNT4, Hsap\GALNT7, Hsap\GALNT14, Hsap\GALNT16, Hsap\GALNTL6, Hsap\GALNT10, Hsap\GALNT12, Hsap\GALNT3" viable FBgn0264776 CG44014 - http://flybase.org/reports/FBgn0264776 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44014, CG14872" IPR012674:Calycin CG44014 11-Aug-17 DroID_v2017_08 - - - - Mmus\Mup21 - viable FBgn0259325 C277 - http://flybase.org/reports/FBgn0259325 gene - - - C277 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing hair,wing" FBgn0043481 l(3)66EFe lethal (3) 66EFe http://flybase.org/reports/FBgn0043481 gene - - - l(3)66EFe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065917 l(2)SH0167 lethal (2) SH0167 http://flybase.org/reports/FBgn0065917 gene - - - l(2)SH0167 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039565 CG4884 - http://flybase.org/reports/FBgn0039565 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002942 - - CG4884 IPR002942:RNA-binding S4 domain CG4884 11-Aug-17 DroID_v2017_08 Drer\si:ch211-206k20.5 - Cele\C47B2.9 Xtro\c6orf203 Mmus\1700021F05Rik Hsap\C6orf203 viable FBgn0003931 snRNA:U4:38AB small nuclear RNA U4 at 38AB http://flybase.org/reports/FBgn0003931 FBgn0003929 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U4 snRNP ; GO:0005687 | inferred from sequence or structural similarity "U4, U4-38AB, U4-1, K3, U4-2, dU4, snRNA:U4:40AB, U4snRNA40AB, CR32879, U4snRNA, snRNA:U4, snRNA:U4:38AB, U4:38AB, U4-38A, U4 snRNA, 38A U4, chr2L:19806693..19806927, U4-snRNA" - CR32879 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031844 CG13771 - http://flybase.org/reports/FBgn0031844 protein_coding_gene - - - CG13771 "IPR029069:HotDog domain, IPR033120:Hotdog acyl-CoA thioesterase (ACOT)-type domain" CG13771 11-Aug-17 DroID_v2017_08 "Drer\acot7, Drer\acot11a, Drer\acot12, Drer\acot9.2, Drer\acot9.1" - "Cele\T07D3.9, Cele\T22B7.7, Cele\F57F4.1" "Xtro\acot12, Xtro\acot11, Xtro\acot7, Xtro\acot9" "Mmus\Acot9, Mmus\Acot7, Mmus\Acot12, Mmus\Acot10, Mmus\Acot11" "Hsap\ACOT9, Hsap\ACOT12, Hsap\ACOT7, Hsap\ACOT11" viable FBgn0034722 Rtf1 Rtf1 http://flybase.org/reports/FBgn0034722 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004343, InterPro:IPR018144 transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from biological aspect of ancestor with PANTHER:PTN000319032 histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | inferred from mutant phenotype RNA polymerase II C-terminal domain phosphoserine binding ; GO:1990269 | inferred from biological aspect of ancestor with PANTHER:PTN000319032" "transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from electronic annotation with InterPro:IPR031102 Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype positive regulation of histone H3-K4 methylation ; GO:0051571 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with N histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype" transcriptionally active chromatin ; GO:0035327 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay Cdc73/Paf1 complex ; GO:0016593 | inferred from biological aspect of ancestor with PANTHER:PTN000319032 "Rtf1, dRtf1, CG10955" "IPR004343:Plus-3 domain, IPR031102:RNA polymerase-associated protein Rtf1" CG10955 11-Aug-17 DroID_v2017_08 Drer\rtf1 Scer\RTF1 Cele\rtfo-1 Xtro\rtf1 Mmus\Rtf1 Hsap\RTF1 "lethal - all die before end of pupal stage,some die during pupal stage,viable,temperature conditional,visible,partially lethal - majority die" "wing,mesothoracic tergum" DRSC04085 I -0.954981181 2.250319973 1.215004919 0.446577289 0.203364778 1.37106682 FBgn0065879 l(2)SH0238 lethal (2) SH0238 http://flybase.org/reports/FBgn0065879 gene - - - l(2)SH0238 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001690 l(1)ESHS11 lethal (1) ESHS11 http://flybase.org/reports/FBgn0001690 - gene - - - l(1)ESHS11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014301 l(3)7-8 lethal (3) 7-8 http://flybase.org/reports/FBgn0014301 - gene - - - l(3)7-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" wing FBgn0051221 CG31221 - http://flybase.org/reports/FBgn0051221 protein_coding_gene - - - "CG7237, anon-EST:Posey251, CG11625, BcDNA:GH25289, CG31221" "IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site" CG31221 11-Aug-17 DroID_v2017_08 - - Cele\F58H1.7 - - Hsap\LRP1B "viable,fertile" FBgn0001836 l(1)ts613 lethal (1) ts613 http://flybase.org/reports/FBgn0001836 - gene - - - l(1)ts613 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0010848 l(3)04713 lethal (3) 04713 http://flybase.org/reports/FBgn0010848 - gene - - - l(3)04713 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive,visible" wing FBgn0001133 grau grauzone http://flybase.org/reports/FBgn0001133 "FBgn0034571, FBgn0053133" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 core promoter proximal region sequence-specific DNA binding ; GO:0000987 | inferred from direct assay transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype egg activation ; GO:0007343 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype homologous chromosome segregation ; GO:0045143 | traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement cellularization ; GO:0007349 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG3282, CG33133, grau" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG33133 11-Aug-17 DroID_v2017_08 "Drer\zgc:153116, Drer\prdm5" - "Cele\fezf-1, Cele\ztf-23, Cele\Y55F3AM.14" - - "Hsap\ZNF805, Hsap\PRDM5, Hsap\ZNF133, Hsap\ZNF544, Hsap\ZNF343" " adult stage | male , adult stage && oogenesis stage , adult stage | female , embryonic stage--pupal stage " ovary

" adult stage && oogenesis stage , oogenesis stage | stage S1-10B && adult stage | female " " follicle cell

, nurse cell

, ovary

, germarium

" "female sterile,recessive,meiotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,lethal,partially,partially lethal - majority die,some die during pupal stage" pole cell DRSC04691 E -0.101847388 -0.919589448 -3.90744993 -0.576881711 -0.621854505 0.108150322 FBgn0010590 Prosbeta1 Proteasome beta1 subunit http://flybase.org/reports/FBgn0010590 FBgn0034064 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839 endopeptidase activity ; GO:0004175 | inferred from sequence or structural similarity with SGD:S000003538" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000003538 "proteasome core complex, beta-subunit complex ; GO:0019774 | inferred from sequence or structural similarity with SGD:S000003538 proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay" "CG8392, l(2)05070, 8392, Prosbeta1, Beta-1, 1(2)05070, beta1, prosbeta1, beta-1" "IPR000243:Peptidase T1A, proteasome beta-subunit, IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR023333:Proteasome B-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG8392 11-Aug-17 DroID_v2017_08 "Drer\psmb12, Drer\psmb9a, Drer\psmb9b, Drer\psmb6" Scer\PRE3 Cele\pbs-1 "Xtro\psmb6, Xtro\psmb9" "Mmus\Psmb6, Mmus\Psmb9" "Hsap\PSMB9, Hsap\PSMB6" "lethal,recessive" DRSC07159 IEK -1.639963265 -2.125326226 -2.902983217 -3.388561255 -0.323908376 -4.129704198 FBgn0037059 CG10510 - http://flybase.org/reports/FBgn0037059 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10510 - CG10510 11-Aug-17 DroID_v2017_08 Drer\ccdc65 - Cele\R05C11.2 Xtro\ccdc65 Mmus\Ccdc65 Hsap\CCDC65 viable DRSC11614 I 1.725416842 -0.234737116 -0.524937808 -0.464230522 -0.296325743 0.054704433 FBgn0034472 CG8517 - http://flybase.org/reports/FBgn0034472 protein_coding_gene protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR005746 disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence or structural similarity with UniProtKB:Q99757 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR005746, InterPro:IPR013766 glycerol ether metabolic process ; GO:0006662 | inferred from electronic annotation with InterPro:IPR005746 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q99757 "mtr, CG8517, 8517" "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR005746:Thioredoxin" CG8517 11-Aug-17 DroID_v2017_08 "Drer\txn, Drer\txn2, Drer\zgc:56493" "Scer\TRX1, Scer\TRX2, Scer\TRX3" "Cele\Y55F3AR.2, Cele\trx-2, Cele\trx-4, Cele\trx-1" Xtro\txn2 "Mmus\Txn2, Mmus\Txn1" "Hsap\TXN, Hsap\TXN2" viable DRSC07205 E -0.024693221 0.767235203 -1.631516982 -0.2398146 1.106853669 0.287317181 FBgn0004443 prd10 paired-like 10 http://flybase.org/reports/FBgn0004443 - gene - - - prd10 - - 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | early FBgn0021975 l(2)k09927 lethal (2) k09927 http://flybase.org/reports/FBgn0021975 - gene - - - l(2)k09927 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262588 CG43125 - http://flybase.org/reports/FBgn0262588 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 molecular_function ; GO:0003674 | no biological data available proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43125 "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG43125 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052707 APC4 Anaphase Promoting Complex subunit 4 http://flybase.org/reports/FBgn0052707 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000002525 "regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from electronic annotation with InterPro:IPR017169, InterPro:IPR024789 anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from sequence or structural similarity with SGD:S000002525" anaphase-promoting complex ; GO:0005680 | inferred from sequence or structural similarity with SGD:S000002525 "CG32707, CG4350, APC4" "IPR024977:Anaphase-promoting complex subunit 4, WD40 domain, IPR017986:WD40-repeat-containing domain, IPR017169:Anaphase-promoting complex subunit 4, metazoa, IPR015943:WD40/YVTN repeat-like-containing domain, IPR024789:Anaphase-promoting complex subunit 4, IPR024790:Anaphase-promoting complex subunit 4 long domain" CG32707 11-Aug-17 DroID_v2017_08 Drer\anapc4 Scer\APC4 Cele\emb-30 Xtro\anapc4 Mmus\Anapc4 Hsap\ANAPC4 "viable,visible" "trichogen cell,tormogen cell" FBgn0031542 CG15414 - http://flybase.org/reports/FBgn0031542 protein_coding_gene - - - CG15414 - CG15414 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC00429 K -0.43623813 0.489870477 0.478888065 -0.22614717 1.704886919 0.552620098 FBgn0004949 amy amethyst http://flybase.org/reports/FBgn0004949 - gene - - - amy - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" pigment cell FBgn0061480 somatostatin somatostatin http://flybase.org/reports/FBgn0061480 gene neuropeptide hormone activity ; GO:0005184 | inferred from direct assay - - "SS, somatostatin" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025885 Inos Inos http://flybase.org/reports/FBgn0025885 FBgn0033176 protein_coding_gene inositol-3-phosphate synthase activity ; GO:0004512 | inferred from sequence or structural similarity with SGD:S000003689 inferred from direct assay phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR002587 inositol biosynthetic process ; GO:0006021 | inferred from sequence or structural similarity with SGD:S000003689 inositol biosynthetic process ; GO:0006021 | inferred from biological aspect of ancestor with PANTHER:PTN000161823 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000161823 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003689 "CG11143, bs36h12.y1, INOS, Inos" "IPR002587:Myo-inositol-1-phosphate synthase, IPR013021:Myo-inositol-1-phosphate synthase, GAPDH-like, IPR016040:NAD(P)-binding domain" CG11143 11-Aug-17 DroID_v2017_08 - Scer\INO1 Cele\inos-1 Xtro\isyna1 Mmus\Isyna1 Hsap\ISYNA1 viable FBgn0014914 anon-4Fh anon-4Fh http://flybase.org/reports/FBgn0014914 - gene - - - anon-4Fh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265732 CR44539 - http://flybase.org/reports/FBgn0265732 non_protein_coding_gene - - - CR44539 - CR44539 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260862 Vti1a Vesicle transport through interaction with t-SNAREs 1a http://flybase.org/reports/FBgn0260862 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with UniProtKB:Q96AJ9 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 "retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity vesicle fusion with Golgi apparatus ; GO:0048280 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 vesicle fusion with Golgi apparatus ; GO:0048280 | inferred from sequence or structural similarity with UniProtKB:Q9JI51 Golgi to vacuole transport ; GO:0006896 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with UniProtKB:Q96AJ9 vesicle fusion ; GO:0006906 | inferred from sequence or structural similarity with SGD:S000004810 protein targeting to vacuole ; GO:0006623 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with UniProtKB:Q9JI51" Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with UniProtKB:Q96AJ9 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with SGD:S000004810 ER to Golgi transport vesicle membrane ; GO:0012507 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 integral component of Golgi membrane ; GO:0030173 | inferred from sequence or structural similarity with SGD:S000004810 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 clathrin-coated vesicle ; GO:0030136 | inferred from sequence or structural similarity with UniProtKB:Q9JI51 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 late endosome membrane ; GO:0031902 | inferred from biological aspect of ancestor with PANTHER:PTN000477446 "Vti1a, Vti1, CG3279, VTI1" "IPR027027:GOSR2/Membrin/Bos1, IPR007705:Vesicle transport v-SNARE, N-terminal, IPR010989:SNARE, IPR000727:Target SNARE coiled-coil homology domain" CG3279 11-Aug-17 DroID_v2017_08 "Drer\vti1b, Drer\vti1a" Scer\VTI1 Cele\vti-1 "Xtro\vti1b, Xtro\vti1a" "Mmus\Vti1b, Mmus\Vti1a" "Hsap\VTI1B, Hsap\VTI1A" DRSC08563 I -0.532764176 2.111289253 -0.281285637 -0.936740179 0.770927513 -0.396170296 FBgn0003162 Pu Punch http://flybase.org/reports/FBgn0003162 - protein_coding_gene GTP cyclohydrolase I activity ; GO:0003934 | inferred from direct assay GTP cyclohydrolase I regulator activity ; GO:0060308 | inferred from direct assay "tetrahydrofolate biosynthetic process ; GO:0046654 | inferred from electronic annotation with InterPro:IPR001474, InterPro:IPR018234 pteridine biosynthetic process ; GO:0006728 | inferred by curator from GO:0003934 preblastoderm mitotic cell cycle ; GO:0035185 | inferred from mutant phenotype pteridine biosynthetic process ; GO:0006728 | inferred from mutant phenotype larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype regulation of GTP cyclohydrolase I activity ; GO:0043095 | inferred from direct assay regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype tetrahydrobiopterin biosynthetic process ; GO:0006729 | inferred from direct assay embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay "GTPCH, CG9441, GTPC, upi, p[Gr], l(2)57Cf, Gr, Pu, DGTPCH, GCH1" "IPR018234:GTP cyclohydrolase I, conserved site, IPR001474:GTP cyclohydrolase I, IPR020602:GTP cyclohydrolase I domain" CG9441 11-Aug-17 DroID_v2017_08 "Drer\gch2, Drer\gch1" Scer\FOL2 Cele\cat-4 Xtro\gch1 Mmus\Gch1 Hsap\GCH1 embryonic stage | early organism

"sterile,lethal,recessive,eye color defective,viable,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,rescuable maternal effect,partially,poor,body color defective" "pigment cell,macrochaeta,eye,trident,embryonic/first instar larval cuticle,cuticle,head,nucleus | embryonic stage 4,nuclear chromosome | embryonic stage 4,chromatin | embryonic stage 4,extended germ band embryo,pole cell,embryonic/larval dorsal trunk,embryonic/larval tracheal system,wing,cephalopharyngeal skeleton" FBgn0026777 Rad23 Rad23 http://flybase.org/reports/FBgn0026777 - protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR015360 polyubiquitin binding ; GO:0031593 | inferred from sequence or structural similarity with UniProtKB:P54727 "regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032434 | inferred from sequence or structural similarity with UniProtKB:P54727 nucleotide-excision repair, DNA damage recognition ; GO:0000715 | inferred from sequence or structural similarity with UniProtKB:P54727" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "rad23, DHR23, CG1836, Rad23, RAD23" "IPR015940:Ubiquitin-associated domain, IPR000626:Ubiquitin domain, IPR004806:UV excision repair protein Rad23, IPR006636:Heat shock chaperonin-binding, IPR009060:UBA-like, IPR015360:XPC-binding domain, IPR029071:Ubiquitin-related domain" CG1836 11-Aug-17 DroID_v2017_08 "Drer\rad23ab, Drer\rad23b, Drer\rad23aa" "Scer\RAD23, Scer\MDY2, Scer\LDH1" Cele\rad-23 Xtro\rad23b "Mmus\Amfr, Mmus\Rad23a, Mmus\Rad23b" "Hsap\RAD23A, Hsap\RAD23B" viable FBgn0039026 CG7029 - http://flybase.org/reports/FBgn0039026 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B - - CG7029 IPR015943:WD40/YVTN repeat-like-containing domain CG7029 11-Aug-17 DroID_v2017_08 Drer\rusc2 - - Xtro\rusc2 Mmus\Rusc2 Hsap\RUSC2 viable DRSC16177 E -0.296893218 -0.159975559 -1.056713404 1.515975083 0.360864618 0.742387924 FBgn0031324 CG14342 - http://flybase.org/reports/FBgn0031324 protein_coding_gene - - - CG14342 IPR032004:Protein of unknown function DUF4790 CG14342 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC00372 IE 0.085131312 -4.555334239 -0.50539243 -2.27714765 1.383548247 -1.487996887 FBgn0029689 CG6428 - http://flybase.org/reports/FBgn0029689 protein_coding_gene asparaginase activity ; GO:0004067 | inferred from biological aspect of ancestor with PANTHER:PTN000194585 asparagine catabolic process ; GO:0006530 | inferred from biological aspect of ancestor with PANTHER:PTN000194585 - "CG6428, CG-6428" "IPR002110:Ankyrin repeat, IPR006033:L-asparaginase, type I, IPR006034:Asparaginase/glutaminase, IPR027474:L-asparaginase, N-terminal, IPR027473:L-asparaginase, C-terminal domain, IPR027475:Asparaginase/glutaminase, active site 2, IPR020683:Ankyrin repeat-containing domain, IPR020827:Asparaginase/glutaminase, active site 1" CG6428 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-74k8.4, Drer\aspg, Drer\si:dkey-9i23.14, Drer\si:ch211-209a2.2" "Scer\YGP1, Scer\ASP3-4, Scer\ASP3-2, Scer\ASP1, Scer\ASP3-3, Scer\ASP3-1, Scer\HOS4, Scer\SPS100, Scer\SOK2, Scer\PHD1" "Cele\C27A7.5, Cele\glna-1, Cele\gls-1, Cele\glna-2" Xtro\aspg "Mmus\Aspg, Mmus\Gls2" "Hsap\ASPG, Hsap\GLS2" "viable,fertile" FBgn0262364 CG43062 - http://flybase.org/reports/FBgn0262364 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43062 - CG43062 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011125 l(1)Q87 lethal (1) Q87 http://flybase.org/reports/FBgn0011125 FBgn0010210 gene - - - l(1)Q87 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034202 CG17287 - http://flybase.org/reports/FBgn0034202 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG17287 "IPR001594:Palmitoyltransferase, DHHC domain, IPR030293:Palmitoyltransferase ZDHHC15" CG17287 11-Aug-17 DroID_v2017_08 "Drer\zdhhc24, Drer\zdhhc2, Drer\zdhhc20b, Drer\zdhhc20a, Drer\zdhhc15b, Drer\zdhhc15a" "Scer\PFA3, Scer\PFA5, Scer\PFA4" "Cele\dhhc-4, Cele\spe-10" "Xtro\pqlc2l, Xtro\zdhhc15, Xtro\zdhhc20, Xtro\zdhhc2" "Mmus\Zdhhc2, Mmus\Zdhhc20, Mmus\Zdhhc24, Mmus\Zdhhc15" "Hsap\ZDHHC20, Hsap\ZDHHC24, Hsap\ZDHHC2, Hsap\ZDHHC15" FBgn0005708 l(1)TK111 lethal (1) TK111 http://flybase.org/reports/FBgn0005708 - gene - - - "l111, l(1)TK111" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0050048 CG30048 - http://flybase.org/reports/FBgn0050048 protein_coding_gene calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 detection of mechanical stimulus ; GO:0050982 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 CG30048 "IPR002859:PKD/REJ-like domain, IPR001024:PLAT/LH2 domain, IPR014010:REJ domain" CG30048 11-Aug-17 DroID_v2017_08 "Drer\pkd1a, Drer\pkd1b" - Cele\F27C1.11 - "Mmus\Loxhd1, Mmus\Pkd1" "Hsap\LOXHD1, Hsap\PKD1L1, Hsap\PKD1" viable FBgn0000295 Cg9E Collagen-like 9E http://flybase.net/reports/FBgn0000295.html gene "DCg9, Cg9" 11-Aug-17 DroID_v2017_08 FBgn0065921 l(2)SH0154 lethal (2) SH0154 http://flybase.org/reports/FBgn0065921 gene - - - "l(2)SH0154, l(2)SH2 0154" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267262 CR45698 - http://flybase.org/reports/FBgn0267262 non_protein_coding_gene - - - CR45698 - CR45698 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039465 Tsp97E Tetraspanin 97E http://flybase.org/reports/FBgn0039465 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 sleep ; GO:0030431 | inferred from expression pattern integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "CG6323, Dm.Tsp97E, Tsp97E, Tspan31" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin" CG6323 11-Aug-17 DroID_v2017_08 "Drer\tspan31, Drer\tspan13a, Drer\tspan13b" - "Cele\M05D6.8, Cele\F01D5.3, Cele\E04D5.4, Cele\F01D5.5, Cele\ZK673.1" "Xtro\tspan31, Xtro\tspan13" "Mmus\Tspan13, Mmus\Tspan31" "Hsap\TSPAN13, Hsap\TSPAN31" viable FBgn0002897 mus211 mutagen-sensitive 211 http://flybase.org/reports/FBgn0002897 - gene - - - mus211 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,radiation sensitive,viable,fertile" FBgn0023008 l(3)S104101 lethal (3) S104101 http://flybase.org/reports/FBgn0023008 - gene - - - "1041/1, 1041/01, l(3)S104101" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0052191 CG32191 - http://flybase.org/reports/FBgn0052191 protein_coding_gene sulfuric ester hydrolase activity ; GO:0008484 | inferred from electronic annotation with InterPro:IPR000917 "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850" - "CG5584, CG32191" "IPR000917:Sulfatase, N-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site" CG32191 11-Aug-17 DroID_v2017_08 "Drer\arsa, Drer\LOC559800, Drer\arsia, Drer\galns, Drer\arsh, Drer\sgsh, Drer\LOC563783, Drer\arsg, Drer\ids, Drer\si:dkey-174i8.1, Drer\LOC101884179" - Cele\sul-3 "Xtro\arsk, Xtro\sgsh, Xtro\arsa.1, Xtro\arsd, Xtro\arsh, Xtro\sts, Xtro\arsb, Xtro\ids, Xtro\arsj, Xtro\arsi" "Mmus\Arsa, Mmus\Arsj, Mmus\Sgsh, Mmus\Arsi, Mmus\Ids, Mmus\Galns, Mmus\Arsb, Mmus\Arsg" "Hsap\ARSH, Hsap\IDS, Hsap\ARSJ, Hsap\ARSF, Hsap\ARSD, Hsap\SGSH, Hsap\ARSI, Hsap\ARSE, Hsap\STS, Hsap\ARSB, Hsap\ARSA, Hsap\ARSG, Hsap\GALNS" viable FBgn0014091 anon-31Eb anonymous at 31E-b http://flybase.org/reports/FBgn0014091 - gene - - - anon-31Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062640 EP873 EP873 http://flybase.org/reports/FBgn0062640 gene - - - "EP(2)0873, EP873" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065790 l(2)SH0430 lethal (2) SH0430 http://flybase.org/reports/FBgn0065790 gene - - - l(2)SH0430 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032407 Pex19 Peroxin 19 http://flybase.org/reports/FBgn0032407 protein_coding_gene - peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:9713 nervous system development ; GO:0007399 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from mutant phenotype peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:9713 "BEST:GH03076, Pex-19, CG5325, Pex19, DmelPex19, PEX19" IPR006708:Pex19 protein CG5325 11-Aug-17 DroID_v2017_08 Drer\pex19 Scer\PEX19 Cele\prx-19 Xtro\pex19 Mmus\Pex19 Hsap\PEX19 viable FBgn0262598 mtsh mitoshell http://flybase.org/reports/FBgn0262598 protein_coding_gene - astral spindle assembly involved in male meiosis ; GO:0055050 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype regulation of mitochondrial fusion ; GO:0010635 | inferred from mutant phenotype - "CG7795, mtsh, mitoshell" IPR001487:Bromodomain CG7795 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035766 eco Establishment of cohesion http://flybase.org/reports/FBgn0035766 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 acetyltransferase activity ; GO:0016407 | inferred from sequence or structural similarity with SGD:S000001923 acetyltransferase activity ; GO:0016407 | inferred from sequence or structural similarity with UniProtKB:P43605 mitotic sister chromatid cohesion ; GO:0007064 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from mutant phenotype nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P43605 "deco, CG8598, eco, Eco1, Deco, ECO" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase, IPR028005:N-acetyltransferase ESCO, zinc-finger, IPR028009:N-acetyltransferase ESCO, acetyl-transferase domain" CG8598 11-Aug-17 DroID_v2017_08 "Drer\esco1, Drer\polk, Drer\polh, Drer\esco2, Drer\rev1, Drer\poli" "Scer\REV1, Scer\ECO1, Scer\RAD30" "Cele\rev-1, Cele\F08F8.4, Cele\polh-1, Cele\polk-1" "Xtro\esco2, Xtro\polk" "Mmus\Polk, Mmus\Poli, Mmus\Polh, Mmus\Rev1, Mmus\Esco1, Mmus\Esco2" "Hsap\POLI, Hsap\REV1, Hsap\POLH, Hsap\POLK, Hsap\ESCO2, Hsap\ESCO1" "mitotic cell cycle defective,viable,visible" "mitotic cell cycle,mitosis & nuclear chromosome,trichogen cell,mesothoracic tergum" DRSC11006 IE 1.559047661 -0.70971592 1.012590465 -1.536702315 -0.663683118 0.008937135 FBgn0061074 l(3)S016603b lethal (3) S016603b http://flybase.org/reports/FBgn0061074 gene - - - "0166/03, l(3)S016603b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004869 l(3)62Cb lethal (3) 62Cb http://flybase.org/reports/FBgn0004869 - gene - - - l(3)62Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0083113 W7 W7 http://flybase.org/reports/FBgn0083113 gene - - - W7 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable wing FBgn0060968 l(3)S030009 lethal (3) S030009 http://flybase.org/reports/FBgn0060968 gene - - - "0300/09, l(3)S030009" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0065120 l(3)SH149 lethal (3) SH149 http://flybase.org/reports/FBgn0065120 gene - - - "l(3)SH149, l(2)SH3 149" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082369 EP3281 EP3281 http://flybase.org/reports/FBgn0082369 gene - - - EP3281 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0041232 CG32395 - http://flybase.org/reports/FBgn0041232 protein_coding_gene taste receptor activity ; GO:0008527 | NOT inferred from sequence or structural similarity G-protein coupled receptor activity ; GO:0004930 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "CG32395, Gr65C1, 65C.1, GR65C.1, Gr65a" IPR013604:7TM chemoreceptor CG32395 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053770 CG33770 - http://flybase.org/reports/FBgn0053770 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14458, CG33770" IPR010512:Protein of unknown function DUF1091 CG33770 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263660 CR43651 - http://flybase.org/reports/FBgn0263660 non_protein_coding_gene - - - "CR43651, pri-mir-14" - CR43651 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060442 l(3)S123304b lethal (3) S123304b http://flybase.org/reports/FBgn0060442 gene - - - "1233/04, l(3)S123304b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001379 l(1)2Bk lethal (1) 2Bk http://flybase.org/reports/FBgn0001379 - gene - - - l(1)2Bk - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041742 l(2)44Fq lethal (2) 44Fq http://flybase.org/reports/FBgn0041742 gene - - - l(2)44Fq - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020331 anon-6A7 anon-6A7 http://flybase.org/reports/FBgn0020331 - gene - - - "6A7, anon-6A7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262009 CG42827 - http://flybase.org/reports/FBgn0262009 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG42827, CG6784" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42827 11-Aug-17 DroID_v2017_08 "Drer\spint2, Drer\col6a4a, Drer\wfikkn2b, Drer\tfpi2, Drer\si:dkeyp-73b11.8, Drer\tfpia, Drer\si:dkey-117n7.5, Drer\spint1b, Drer\ambp, Drer\wu:fb59d01, Drer\wfikkn1, Drer\spint1a" - "Cele\R12A1.3, Cele\T21D12.12, Cele\tag-290, Cele\C54D10.10, Cele\piit-1" "Xtro\spint2, Xtro\spint1, Xtro\ambp, Xtro\tfpi2" "Mmus\Tfpi, Mmus\Eppin, Mmus\Spint2, Mmus\Wfdc6b, Mmus\Wfdc6a, Mmus\Spint1, Mmus\Spint3, Mmus\Wfdc8, Mmus\Ambp, Mmus\Spint4, Mmus\Tfpi2, Mmus\Spint5" "Hsap\TFPI, Hsap\TFPI2, Hsap\AMBP, Hsap\SPINT3, Hsap\WFDC8, Hsap\SPINT2, Hsap\EPPIN-WFDC6, Hsap\WFIKKN1, Hsap\SPINT4, Hsap\WFDC6, Hsap\SPINT1" viable FBgn0028597 l(2)k05113a lethal (2) k05113a http://flybase.org/reports/FBgn0028597 gene - - - "l(2)k05113, l(2)k05113a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261378 mgg maggot http://flybase.org/reports/FBgn0261378 gene - - - "mgg, mgt" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "dorsal appendage,ovary" FBgn0041826 KA16-II KA16-II http://flybase.org/reports/FBgn0041826 gene - - - KA16-II - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" FBgn0260264 GSd222 - http://flybase.org/reports/FBgn0260264 gene - - - GSd222 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004675 E(A[53g]) Enhancer of abnormal abdomen-53g http://flybase.org/reports/FBgn0004675 - gene - - - "E(A), E(A[53g])" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266933 CR45384 - http://flybase.org/reports/FBgn0266933 non_protein_coding_gene - - - CR45384 - CR45384 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260296 GSd421 - http://flybase.org/reports/FBgn0260296 gene - - - GSd421 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029835 CG5921 - http://flybase.org/reports/FBgn0029835 protein_coding_gene actin filament binding ; GO:0051015 | inferred from electronic annotation with InterPro:IPR030237 spectrin binding ; GO:0030507 | inferred from sequence or structural similarity with HGNC:12597 sensory perception of sound ; GO:0007605 | inferred from electronic annotation with InterPro:IPR030237 G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from sequence or structural similarity with HGNC:12597 apical part of cell ; GO:0045177 | inferred from sequence or structural similarity with HGNC:12597 CG5921 "IPR001478:PDZ domain, IPR030237:Harmonin" CG5921 11-Aug-17 DroID_v2017_08 "Drer\pdzd7a, Drer\grip2b, Drer\inadl, Drer\dfnb31a, Drer\slc9a3r1, Drer\dlg5a, Drer\pdzd7b, Drer\pard3bb, Drer\grid2ipa, Drer\ush1c, Drer\il16, Drer\si:dkey-92i15.4, Drer\grip1, Drer\lnx1" - Cele\dlg-1 "Xtro\grip2, Xtro\grid2ip, Xtro\lnx1, Xtro\grip1, Xtro\dlg5" "Mmus\Mpdz, Mmus\Whrn, Mmus\Lnx1, Mmus\Grid2ip, Mmus\Dlg5, Mmus\Grasp, Mmus\Grip2, Mmus\Pdzph1, Mmus\Il16, Mmus\Pdzd2, Mmus\Patj, Mmus\Pdzd11, Mmus\Ush1c, Mmus\Grip1" "Hsap\FRMPD2, Hsap\USH1C, Hsap\PDZD2, Hsap\PARD3B, Hsap\LNX1, Hsap\MPDZ, Hsap\PATJ, Hsap\GRID2IP, Hsap\WHRN, Hsap\GRIP1, Hsap\DLG5, Hsap\IL16, Hsap\GRASP" viable FBgn0042179 CG18869 - http://flybase.org/reports/FBgn0042179 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "anon-WO0153538.77, anon-WO0140519.104, CG18869, Tes36" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG18869 11-Aug-17 DroID_v2017_08 "Drer\ugt2a5, Drer\ugt8, Drer\ugt5d1, Drer\ugt5c2, Drer\ugt1b2, Drer\ugt1b5, Drer\ugt2b6, Drer\ugt5a5, Drer\ugt5b6, Drer\ugt2b1, Drer\ugt5a4, Drer\ugt5b3, Drer\ugt5c1, Drer\ugt5b2, Drer\ugt5a2, Drer\ugt1ab, Drer\ugt5c3, Drer\ugt5b1, Drer\zgc:172315, Drer\ugt1b7, Drer\ugt5g2, Drer\ugt2b5, Drer\ugt1b4, Drer\ugt2a2, Drer\ugt5e1, Drer\ugt1b3, Drer\ugt2a6, Drer\ugt5f1, Drer\ugt5a1, Drer\ugt5g1, Drer\ugt2b3" Scer\ATG26 "Cele\ugt-40, Cele\ugt-50, Cele\ugt-56, Cele\ugt-57, Cele\ugt-28, Cele\C03A7.12, Cele\ugt-15, Cele\ugt-17, Cele\ugt-5, Cele\ugt-58, Cele\ugt-14, Cele\ugt-23, Cele\ugt-60, Cele\ugt-65, Cele\ugt-33, Cele\ugt-13, Cele\ugt-42, Cele\ugt-34, Cele\ugt-43, Cele\ugt-19, Cele\ugt-36, Cele\ugt-30, Cele\ugt-52, Cele\ugt-59, Cele\ugt-20, Cele\ugt-51, Cele\C55H1.1, Cele\Y43D4A.2, Cele\ugt-63, Cele\ugt-32, Cele\ugt-2, Cele\ugt-16, Cele\ugt-35, Cele\ugt-1, Cele\ugt-64, Cele\ugt-6, Cele\ugt-8, Cele\ugt-53, Cele\ugt-41, Cele\ugt-21, Cele\ugt-7, Cele\ugt-46, Cele\ugt-25, Cele\ugt-37, Cele\ugt-11, Cele\K04A8.10, Cele\ugt-44, Cele\ugt-18, Cele\ugt-3, Cele\ugt-27, Cele\ugt-38, Cele\ugt-12, Cele\ugt-49, Cele\C23G10.6, Cele\ugt-55, Cele\C03A7.13, Cele\ugt-31, Cele\ugt-9, Cele\ugt-47, Cele\ugt-39, Cele\ugt-45, Cele\ugt-4, Cele\ugt-61, Cele\F10D2.8, Cele\H23N18.4, Cele\ugt-26, Cele\ugt-10" "Xtro\ugt3a2, Xtro\ugt8, Xtro\ugt1a6, Xtro\ugt2b4, Xtro\ugt2a1" "Mmus\Ugt2b38, Mmus\Ugt1a5, Mmus\Ugt8a, Mmus\Ugt2b1, Mmus\Ugt1a9, Mmus\Ugt2b5, Mmus\Ugt1a7c, Mmus\Ugt2b35, Mmus\Ugt2a3, Mmus\Ugt3a2, Mmus\Ugt2b34, Mmus\Ugt1a1, Mmus\Ugt1a6b, Mmus\Ugt3a1, Mmus\Ugt2a1, Mmus\Ugt1a2, Mmus\Ugt2b37, Mmus\Ugt2b36" "Hsap\UGT1A10, Hsap\UGT1A1, Hsap\UGT2B7, Hsap\UGT2B17, Hsap\UGT2B28, Hsap\UGT8, Hsap\UGT1A8, Hsap\UGT1A6, Hsap\UGT2A2, Hsap\UGT2B11, Hsap\UGT1A7, Hsap\UGT2B15, Hsap\UGT1A5, Hsap\UGT3A2, Hsap\UGT1A4, Hsap\UGT3A1, Hsap\UGT1A3, Hsap\UGT2B4, Hsap\UGT1A9, Hsap\UGT2A3, Hsap\UGT2B10" viable FBgn0004981 Bit Bitten http://flybase.org/reports/FBgn0004981 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Bit - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive,flight defective" wing FBgn0260029 siren5 siren 5 http://flybase.org/reports/FBgn0260029 gene - - - siren5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0038260 CG14855 - http://flybase.org/reports/FBgn0038260 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG14855 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG14855 11-Aug-17 DroID_v2017_08 "Drer\LOC101884074, Drer\slc22a13, Drer\zmp:0000001102, Drer\LOC100334012, Drer\slc22a5, Drer\sv2, Drer\oatx, Drer\slc22a21, Drer\slc22a7b.1, Drer\slc22a7b.2, Drer\slc22a6l, Drer\zgc:175176, Drer\slc22a7b.3" "Scer\AQR1, Scer\HXT9, Scer\QDR2, Scer\TPO2, Scer\QDR3, Scer\HXT2, Scer\DTR1, Scer\TPO3, Scer\FLR1, Scer\HXT5, Scer\TPO1, Scer\QDR1, Scer\GIT1, Scer\PHO84, Scer\YHK8" "Cele\Y66D12A.13, Cele\T22F7.1, Cele\oat-1, Cele\B0252.3, Cele\C53B4.1, Cele\B0361.11, Cele\ZK892.3, Cele\Y57G11C.23, Cele\oct-1, Cele\C46C2.2, Cele\C06H5.6, Cele\Y51A2D.18" Xtro\slc22a6 "Mmus\Slc22a7, Mmus\Slc22a14, Mmus\Slc22a16, Mmus\Svop, Mmus\Slc22a29, Mmus\Slc22a2, Mmus\Slc22a4, Mmus\Slc22a23, Mmus\Slc22a30, Mmus\Slc22a6, Mmus\Slc22a17, Mmus\Slc22a22, Mmus\Slc22a8, Mmus\Slc22a27, Mmus\Sv2c, Mmus\Slc22a21, Mmus\Slc22a5, Mmus\Slc22a26, Mmus\Slc22a28, Mmus\Slc22a20, Mmus\Slc22a19" "Hsap\SLC22A12, Hsap\SLC22A10, Hsap\SLC22A2, Hsap\SLC22A7, Hsap\SVOP, Hsap\SLC22A11, Hsap\SLC22A23, Hsap\SV2C, Hsap\SLC22A5, Hsap\SLC22A25, Hsap\SLC22A8, Hsap\SLC22A9, Hsap\SLC22A4, Hsap\SLC22A1, Hsap\SV2B, Hsap\SLC22A6, Hsap\SLC22A24" viable FBgn0032484 kek4 kekkon4 http://flybase.org/reports/FBgn0032484 protein_coding_gene - negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | NOT inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 proteinaceous extracellular matrix ; GO:0005578 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG9431, CT26742, kek4" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR003599:Immunoglobulin subtype, IPR003591:Leucine-rich repeat, typical subtype" CG9431 11-Aug-17 DroID_v2017_08 "Drer\bgnb, Drer\islr2, Drer\zgc:113307, Drer\prelp, Drer\lrrc38b, Drer\lrtm1, Drer\omd, Drer\lrtm2b, Drer\fmodb, Drer\LOC101883217, Drer\fmoda, Drer\lrrc38a, Drer\lrrc4.2, Drer\tpbgl, Drer\rtn4rl2b, Drer\lrit3a, Drer\si:dkey-6n6.1, Drer\lrit3b, Drer\LOC101882074, Drer\lrit1a, Drer\si:dkey-90m5.4, Drer\lrtm2a, Drer\si:dkey-32e6.6, Drer\kera, Drer\lrit1b, Drer\si:dkey-52j6.3, Drer\lrrc24, Drer\lrit2, Drer\ecm2, Drer\lum, Drer\LOC101882092" - "Cele\lron-3, Cele\pxn-1, Cele\iglr-2, Cele\iglr-3" "Xtro\slitrk1, Xtro\LOC100488256, Xtro\lrrc4, Xtro\lrrc24, Xtro\lrrc52, Xtro\amigo2, Xtro\lrit3, Xtro\slitrk6, Xtro\lrit2, Xtro\lrtm2, Xtro\islr2" "Mmus\Slitrk6, Mmus\Prelp, Mmus\Lrrc38, Mmus\Lrtm1, Mmus\Lrtm2, Mmus\Lrit2, Mmus\Flrt2, Mmus\Lrrc55, Mmus\Slitrk1, Mmus\Ecm2, Mmus\Tril, Mmus\Lum, Mmus\Lrit1, Mmus\Amigo3, Mmus\Kera, Mmus\Lrrc52, Mmus\Omd, Mmus\Aspn, Mmus\Lrrc26, Mmus\Fmod, Mmus\Slitrk5, Mmus\Lrrc24, Mmus\Islr, Mmus\Lrit3, Mmus\Islr2" "Hsap\ASPN, Hsap\TPBG, Hsap\LRRC26, Hsap\SLITRK5, Hsap\OMD, Hsap\AMIGO2, Hsap\PRELP, Hsap\FLRT2, Hsap\LRRC52, Hsap\LRIT3, Hsap\LRIT2, Hsap\LRTM2, Hsap\ISLR, Hsap\LRRC24, Hsap\LRRC55, Hsap\ECM2, Hsap\LRTM1, Hsap\KERA, Hsap\LRRC38, Hsap\LUM, Hsap\ISLR2, Hsap\LRIT1, Hsap\FMOD" "auditory perception defective,viable" FBgn0065469 l(2)SH1335 lethal (2) SH1335 http://flybase.org/reports/FBgn0065469 gene - - - "l(2)SH1335, l(2)SH2 1335" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028124 l(3)S058209b lethal (3) S058209b http://flybase.org/reports/FBgn0028124 gene - - - "0582/09, l(3)S058209, l(3)S058209b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0037176 CG14456 - http://flybase.org/reports/FBgn0037176 protein_coding_gene - - - CG14456 IPR010512:Protein of unknown function DUF1091 CG14456 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000160 bas bang-sensitive http://flybase.org/reports/FBgn0000160 - gene - mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype - "bas-A, bas" - - 11-Aug-17 DroID_v2017_08 - - - - - - "bang sensitive,neurophysiology defective,paralytic,behavior defective,semidominant,heat sensitive,recessive" abdominal 1 dorsal longitudinal muscle FBgn0037578 CG9601 - http://flybase.org/reports/FBgn0037578 protein_coding_gene ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity ; GO:0046404 | inferred from biological aspect of ancestor with PANTHER:PTN001382891 polynucleotide 3'-phosphatase activity ; GO:0046403 | inferred from biological aspect of ancestor with PANTHER:PTN001382891 nucleotide kinase activity ; GO:0019201 | inferred from biological aspect of ancestor with PANTHER:PTN001382891 nucleotide kinase activity ; GO:0019201 | inferred from sequence or structural similarity with HGNC:9154 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN001382891 polynucleotide 3' dephosphorylation ; GO:0098506 | inferred from biological aspect of ancestor with PANTHER:PTN001382891 DNA 3' dephosphorylation involved in DNA repair ; GO:0098504 | inferred from biological aspect of ancestor with PANTHER:PTN001382891 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with HGNC:9154 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:9154 "CG9601, PNKP, 28573184" "IPR006549:HAD-superfamily hydrolase,subfamily IIIA, IPR006550:Polynucleotide kinase 3-phosphatase, metazoan, IPR006551:Polynucleotide 3'-phosphatase, IPR008984:SMAD/FHA domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013954:Polynucleotide kinase 3 phosphatase, IPR023214:HAD-like domain" CG9601 11-Aug-17 DroID_v2017_08 "Drer\aptx, Drer\pnkp" "Scer\HNT3, Scer\TPP1" Cele\F21D5.5 "Xtro\aptx, Xtro\pnkp" "Mmus\Aptx, Mmus\Pnkp" "Hsap\APTX, Hsap\PNKP" viable FBgn0011141 l(1)Q217 lethal (1) Q217 http://flybase.org/reports/FBgn0011141 FBgn0010210 gene - - - l(1)Q217 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267504 28SrRNA:CR45844 28S ribosomal RNA:CR45844 http://flybase.org/reports/FBgn0267504 rRNA_gene - - - "28SrRNA:CR45844, CR45844" - CR45844 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000762 fs(1)A508 female sterile (1) A508 http://flybase.org/reports/FBgn0000762 - gene - - - "fs(1)508, fs(1)A508" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,visible" "egg,macrochaeta" FBgn0038639 CG7705 - http://flybase.org/reports/FBgn0038639 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7705 - CG7705 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0026755 Ugt37b1 UDP-glycosyltransferase 37b1 http://flybase.org/reports/FBgn0026755 FBgn0031790 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 UDP-glycosyltransferase activity ; GO:0008194 | inferred from sequence or structural similarity with UniProtKB:P18569 UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with UniProtKB:P18569 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 integral component of membrane ; GO:0016021 | inferred from sequence model "AC 005285A, DmeUgt37b1, CG9481, Ugt37b1" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG9481 11-Aug-17 DroID_v2017_08 "Drer\ugt5a4, Drer\ugt1b2, Drer\ugt5g1, Drer\ugt2a2, Drer\ugt5e1, Drer\ugt2a6, Drer\ugt2a5, Drer\ugt2b3, Drer\ugt8, Drer\ugt5a5, Drer\ugt2b5, Drer\ugt5d1, Drer\ugt5b6, Drer\ugt2b1, Drer\ugt5g2, Drer\ugt5b2, Drer\ugt2b6, Drer\ugt1ab, Drer\ugt5c2, Drer\ugt1b7, Drer\ugt1b3, Drer\zgc:172315, Drer\ugt5a1, Drer\ugt5a2, Drer\ugt5f1, Drer\ugt1b5, Drer\ugt5b1, Drer\ugt1b4, Drer\ugt5b3, Drer\ugt5c1, Drer\ugt5c3" Scer\ATG26 "Cele\ugt-60, Cele\ugt-7, Cele\ugt-4, Cele\Y43D4A.2, Cele\ugt-59, Cele\ugt-32, Cele\ugt-2, Cele\ugt-18, Cele\ugt-40, Cele\ugt-57, Cele\ugt-50, Cele\ugt-61, Cele\ugt-3, Cele\ugt-42, Cele\ugt-63, Cele\K04A8.10, Cele\ugt-46, Cele\ugt-43, Cele\ugt-13, Cele\ugt-39, Cele\ugt-48, Cele\ugt-6, Cele\ugt-20, Cele\ugt-21, Cele\ugt-27, Cele\ugt-55, Cele\ugt-1, Cele\ugt-10, Cele\ugt-58, Cele\ugt-36, Cele\ugt-37, Cele\ugt-54, Cele\ugt-11, Cele\ugt-31, Cele\ugt-35, Cele\ugt-38, Cele\ugt-53, Cele\ugt-52, Cele\ugt-44, Cele\ugt-17, Cele\C03A7.13, Cele\ugt-19, Cele\ugt-14, Cele\ugt-45, Cele\ugt-5, Cele\ugt-9, Cele\ugt-23, Cele\ugt-30, Cele\ugt-62, Cele\ugt-56, Cele\C23G10.6, Cele\ugt-51, Cele\F10D2.8, Cele\ugt-47, Cele\ugt-22, Cele\H23N18.4, Cele\ugt-65, Cele\ugt-24, Cele\ugt-28, Cele\ugt-34, Cele\C03A7.12, Cele\ugt-15, Cele\ugt-41, Cele\ugt-29, Cele\ugt-33, Cele\ugt-16, Cele\ugt-26, Cele\ugt-49, Cele\ugt-8, Cele\C55H1.1, Cele\ugt-25, Cele\ugt-12" "Xtro\ugt8, Xtro\ugt2b4, Xtro\ugt1a6, Xtro\ugt3a2, Xtro\ugt2a1" "Mmus\Ugt2b36, Mmus\Ugt1a7c, Mmus\Ugt1a5, Mmus\Ugt3a1, Mmus\Ugt1a1, Mmus\Ugt1a2, Mmus\Ugt2b38, Mmus\Ugt3a2, Mmus\Ugt2b34, Mmus\Ugt2a1, Mmus\Ugt2b35, Mmus\Ugt1a6b, Mmus\Ugt2a3, Mmus\Ugt8a, Mmus\Ugt2b5, Mmus\Ugt2b1, Mmus\Ugt2b37, Mmus\Ugt1a9" "Hsap\UGT2B4, Hsap\UGT1A8, Hsap\UGT1A7, Hsap\UGT8, Hsap\UGT1A10, Hsap\UGT2B15, Hsap\UGT3A1, Hsap\UGT3A2, Hsap\UGT2A2, Hsap\UGT1A5, Hsap\UGT1A6, Hsap\UGT2A3, Hsap\UGT1A3, Hsap\UGT2B17, Hsap\UGT2B7, Hsap\UGT1A9, Hsap\UGT2B10, Hsap\UGT2B11, Hsap\UGT2B28, Hsap\UGT1A1, Hsap\UGT1A4" viable FBgn0265180 CG44245 - http://flybase.org/reports/FBgn0265180 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mesoderm development ; GO:0007498 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "CG9480, CG44245" - CG44245 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259520 B2001 - http://flybase.org/reports/FBgn0259520 gene - - - B2001 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,anterior crossvein,wing vein L3,arista" FBgn0032003 CG8349 - http://flybase.org/reports/FBgn0032003 protein_coding_gene cytidine deaminase activity ; GO:0004126 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 cytidine deamination ; GO:0009972 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 CG8349 "IPR002125:Cytidine and deoxycytidylate deaminases, zinc-binding, IPR016192:APOBEC/CMP deaminase, zinc-binding, IPR016193:Cytidine deaminase-like, IPR006263:Cytidine deaminase, homodimeric" CG8349 11-Aug-17 DroID_v2017_08 "Drer\cda, Drer\zgc:103586" Scer\CDD1 "Cele\cdd-1, Cele\cdd-2" - "Mmus\Maged2, Mmus\Cda, Mmus\Gm15114, Mmus\Maged1, Mmus\Tro" "Hsap\MAGED4, Hsap\MAGED4B, Hsap\MAGED2, Hsap\MAGED1, Hsap\CDA, Hsap\TRO" FBgn0036740 Vps60 Vacuolar protein sorting 60 http://flybase.org/reports/FBgn0036740 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vacuolar transport ; GO:0007034 | inferred from electronic annotation with InterPro:IPR005024 epithelium development ; GO:0060429 | inferred from mutant phenotype negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from mutant phenotype positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from sequence or structural similarity with SGD:S000002894 germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype negative regulation of epithelial cell proliferation ; GO:0050680 | inferred from mutant phenotype ESCRT III complex ; GO:0000815 | non-traceable author statement "bs36h07.y1, anon-74EFb, VPS60, Chmp5, Vps60, CG6259" IPR005024:Snf7 family CG6259 11-Aug-17 DroID_v2017_08 "Drer\chmp5b, Drer\chmp5a" Scer\VPS60 Cele\vps-60 Xtro\chmp5 Mmus\Chmp5 Hsap\CHMP5 "lethal,increased cell number,lethal - all die before end of pupal stage,some die during pupal stage" "epithelium,somatic clone,interfollicle cell,female germline cyst" FBgn0263462 snoRNA:Dek-a - http://flybase.org/reports/FBgn0263462 snoRNA_gene - - - "snoRNA:Dek-a, snoRNA:dek-a, snoHACA_04, chr2R:12372273..12372375" - CR43577 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030012 CG18262 - http://flybase.org/reports/FBgn0030012 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG18262 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG18262 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-210j14.3, Drer\LOC100534908, Drer\LOC101883936, Drer\si:dkey-226l10.6, Drer\LOC101886221, Drer\zgc:175107, Drer\zgc:110249, Drer\LOC100537687, Drer\LOC100002469, Drer\LOC100333228, Drer\LOC100537377, Drer\zgc:174288, Drer\si:ch211-161m3.4, Drer\si:ch211-241e1.5, Drer\si:ch73-367f21.6, Drer\zgc:171551, Drer\znf1161, Drer\znf970, Drer\zgc:162936, Drer\zgc:113348, Drer\si:ch73-138e16.4, Drer\si:ch73-367f21.4, Drer\LOC101885996, Drer\si:rp71-1h20.5, Drer\zgc:171220, Drer\zgc:113294, Drer\LOC100001832, Drer\LOC101884416, Drer\zgc:113377, Drer\znf971, Drer\si:ch1073-127d16.1, Drer\zgc:163077, Drer\zgc:113295, Drer\si:ch211-110e21.4, Drer\LOC100535458, Drer\LOC100535934, Drer\si:ch73-299h12.6, Drer\LOC103910593, Drer\zgc:113030, Drer\si:ch211-222k6.1, Drer\znf1178, Drer\si:ch73-299h12.4, Drer\LOC798256, Drer\zgc:113343, Drer\znf1157, Drer\si:ch211-161m3.2, Drer\znf995, Drer\zgc:153116, Drer\klf1, Drer\LOC103908714, Drer\zgc:174263, Drer\blf, Drer\LOC101884439, Drer\si:dkey-15h8.16, Drer\znf1154, Drer\si:dkey-253d23.8, Drer\si:dkeyp-53d3.3, Drer\si:ch211-202h22.10, Drer\si:dkey-1b17.8" Scer\AZF1 "Cele\M03D4.4, Cele\hinf-1, Cele\Y55F3AM.14" - "Mmus\Zfp62, Mmus\Zfp729a, Mmus\Zfp870, Mmus\Zfp422" "Hsap\ZFP62, Hsap\ZNF22, Hsap\ZNF320, Hsap\ZNF791, Hsap\ZNF630, Hsap\ZNF570, Hsap\ZNF132" FBgn0261400 didy disjunction dysfunction http://flybase.org/reports/FBgn0261400 protein_coding_gene - - - didy - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263744 CR43669 - http://flybase.org/reports/FBgn0263744 pseudogene_attribute - - - "CR43669, CG31782" - CR43669 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020501 CU58 Cible d'Ubx 58 http://flybase.org/reports/FBgn0020501 - gene - - - "58, CU58" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031287 CG4291 - http://flybase.org/reports/FBgn0031287 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000690, InterPro:IPR003604, InterPro:IPR013085 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000690, InterPro:IPR003604" "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000001495 inferred from sequence or structural similarity with protein_id:AAC34810 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000001495 inferred from sequence or structural similarity with protein_id:AAC34810 U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with protein_id:AAC34810 precatalytic spliceosome ; GO:0071011 | inferred from direct assay CG4291 "IPR000690:Matrin/U1-C, C2H2-type zinc finger, IPR001202:WW domain, IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013085:U1-C, C2H2-type zinc finger, IPR013087:Zinc finger C2H2-type" CG4291 11-Aug-17 DroID_v2017_08 Drer\wbp4 - Cele\F56G4.4 Xtro\wbp4 Mmus\Wbp4 Hsap\WBP4 viable FBgn0265213 fs(2)Z2-1896 - http://flybase.org/reports/FBgn0265213 gene - - - fs(2)Z2-1896 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0022400 Gase2 Gastric serine protease 2 http://flybase.org/reports/FBgn0022400 - gene - - - Gase2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003135 pph polyphenic http://flybase.org/reports/FBgn0003135 - gene - - - "pph-61, pph" - - 11-Aug-17 DroID_v2017_08 - - - - - - "small body,viable,female semi-sterile,recessive" "eye,wing,scutellar bristle" FBgn0020830 l(2)PW8 "Pullman, Washington 8" http://flybase.org/reports/FBgn0020830 - gene - - - l(2)PW8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,female" FBgn0039776 PH4alphaEFB prolyl-4-hydroxylase-alpha EFB http://flybase.org/reports/FBgn0039776 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 endomembrane system ; GO:0012505 | inferred from direct assay "CG1473, CG12088, BcDNA:SD05564, PH4alphaEFB, CG31022, PH4alpha-EFB, PH4-aEFB" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG31022 11-Aug-17 DroID_v2017_08 "Drer\p4ha3, Drer\p4ha2, Drer\zgc:152670, Drer\p4htm, Drer\zgc:158254, Drer\p4ha1a, Drer\p4ha1b" - "Cele\Y43F8B.19, Cele\C14E2.4, Cele\phy-4, Cele\dpy-18, Cele\phy-3, Cele\phy-2" "Xtro\p4ha3, Xtro\p4ha2, Xtro\LOC100492280, Xtro\p4ha1" "Mmus\P4ha1, Mmus\P4ha2, Mmus\P4htm, Mmus\P4ha3" "Hsap\P4HTM, Hsap\P4HA1, Hsap\P4HA2, Hsap\P4HA3" "viable,fertile" DRSC14473 K 0.539286455 -0.83753037 0.923775169 0.047495267 -1.611860053 -1.067961506 FBgn0037949 CG17360 - http://flybase.org/reports/FBgn0037949 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab39 biological_process ; GO:0008150 | no biological data available Golgi apparatus ; GO:0005794 | inferred from direct assay "BcDNA:RH29885, CG17360" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG17360 11-Aug-17 DroID_v2017_08 Drer\plekhm2 - - Xtro\plekhm2 Mmus\Plekhm2 Hsap\PLEKHM2 "viable,fertile" FBgn0041103 nht no hitter http://flybase.org/reports/FBgn0041103 protein_coding_gene "transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000388601 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000388601 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000388601 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from sequence or structural similarity with HGNC:11538 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Taf12L transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN000388601" regulation of gene expression ; GO:0010468 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000388601 spermatogenesis ; GO:0007283 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11538 transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11538 transcription factor TFIID complex ; GO:0005669 | inferred from biological aspect of ancestor with PANTHER:PTN000388601 male germ cell nucleus ; GO:0001673 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "dTAF4L, Nht, TFIID, dTAF[[II]]110, dmTAF4b, CG15259, BG:DS07851.6, nht, TAF4, DS07851.6" IPR007900:Transcription initiation factor TFIID component TAF4 CG15259 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-219c3.2, Drer\taf4b, Drer\taf4a, Drer\LOC101885225" Scer\TAF4 Cele\taf-4 Xtro\taf4 "Mmus\Taf4, Mmus\Taf4b" "Hsap\TAF4, Hsap\TAF4B" "male sterile,viable,body color defective" mesothoracic tergum FBgn0053359 5SrRNA:CR33359 5SrRNA:CR33359 http://flybase.org/reports/FBgn0053359 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33359, 5SrRNA:CR33359" - CR33359 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033516 CG12898 - http://flybase.org/reports/FBgn0033516 protein_coding_gene - - - CG12898 IPR010512:Protein of unknown function DUF1091 CG12898 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003087 pim pimples http://flybase.org/reports/FBgn0003087 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P42286 Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype mitotic sister chromatid separation ; GO:0051306 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | non-traceable author statement epithelial cell development ; GO:0002064 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | traceable author statement digestive tract mesoderm development ; GO:0007502 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006940 cytoplasm ; GO:0005737 | inferred from direct assay "PIM, l(2)31Df, CG5052, pim, Pim, frag2" IPR006940:Securin sister-chromatid separation inhibitor CG5052 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , embryonic stage&&pupal stage&&adult stage , embryonic stage | early , larval stage | third instar " " embryonic central nervous system

,

ubiquitous " "mitotic cell cycle defective,recessive,lethal,wild-type,increased cell death,cytokinesis defective,lethal - all die before end of embryonic stage,some die during embryonic stage,sterile,visible,neuroanatomy defective,viable" "gonad,gonadal sheath proper primordium,visceral mesoderm,embryonic Malpighian tubule,Malpighian tubule,embryonic head,embryonic/first instar larval cuticle,epidermal cell,centrosome,epithelial cell,metaphase plate,mitotic M phasenos.bcd3'UTR.TGCN4,nuclear chromosomenos.bcd3'UTR.TGCN4,mitotic M phaseda.G32,nuclear chromosomeda.G32,eye,ommatidium,wing,metaphase platenos.bcd3'UTR.TGCN4,embryonic/larval neuroblast,ganglion mother cell" DRSC03591 E -0.492675508 -1.179457277 1.667406989 -4.573222412 0.868451076 0.215224666 FBgn0000947 fs(2)A17 female sterile (2) A17 http://flybase.org/reports/FBgn0000947 - gene - - - fs(2)A17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "egg chamber,ovary,oocyte" FBgn0085729 CG42227 - http://flybase.org/reports/FBgn0085729 protein_coding_gene - - - CG42227 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053635 CG33635 - http://flybase.org/reports/FBgn0053635 protein_coding_gene - "retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with SGD:S000000198 vesicle-mediated transport ; GO:0016192 | inferred from biological aspect of ancestor with PANTHER:PTN000566465" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011691 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000566465 Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity with SGD:S000000198 "BP1075, HDC00027, CG33635" "IPR007305:Vesicle transport protein, Got1/SFT2-like, IPR011691:Vesicle transport protein, SFT2-like" CG33635 11-Aug-17 DroID_v2017_08 "Drer\zgc:112392, Drer\sft2d1, Drer\sft2d3, Drer\zgc:110788" Scer\SFT2 "Cele\F27D4.7, Cele\sftd-3" "Xtro\sft2d2, Xtro\sft2d3, Xtro\sft2d1" "Mmus\Sft2d3, Mmus\Sft2d2, Mmus\Sft2d1" "Hsap\SFT2D2, Hsap\SFT2D1, Hsap\SFT2D3" viable FBgn0039309 CG11891 - http://flybase.org/reports/FBgn0039309 protein_coding_gene - - - "CT37044, CG33091, CG11891" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG11891 11-Aug-17 DroID_v2017_08 - - "Cele\E02C12.9, Cele\Y45G12C.4, Cele\D1044.1, Cele\E02C12.8, Cele\E02C12.6, Cele\H37A05.2, Cele\F58B4.5, Cele\C29F7.1, Cele\dhs-27, Cele\C18B10.6, Cele\H06H21.8, Cele\nhr-246, Cele\F56A4.5, Cele\E02C12.10" - - - FBgn0029120 Su(Sxl[fs])46 Su(Sxl[fs])46 http://flybase.org/reports/FBgn0029120 gene - - - Su(Sxl[fs])46 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031032 CG14204 - http://flybase.org/reports/FBgn0031032 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" wing disc development ; GO:0035220 | inferred from genetic interaction with Bx chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp - CG14204 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG14204 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-7, Cele\oac-55, Cele\oac-54, Cele\oac-6, Cele\rhy-1, Cele\ndg-4, Cele\oac-50, Cele\nrf-6, Cele\oac-9, Cele\oac-53, Cele\oac-39, Cele\oac-5, Cele\oac-31, Cele\oac-32, Cele\oac-14, Cele\oac-3, Cele\oac-46, Cele\oac-20" Xtro\LOC101732251 Mmus\Oacyl - FBgn0283463 mir-997-2 mir-997-2 stem loop http://flybase.org/reports/FBgn0283463 miRNA_gene - - - "mir-997-2, dme-mir-997-2, miR-997, hp-mir-997-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028403 Shaq Shaq http://flybase.org/reports/FBgn0028403 gene - - - Shaq - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022147 l(2)k06019 lethal (2) k06019 http://flybase.org/reports/FBgn0022147 - gene - - - l(2)k06019 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" crystal cell FBgn0263606 Hsc20 Heat shock protein cognate 20 http://flybase.org/reports/FBgn0263606 protein_coding_gene ATPase activator activity ; GO:0001671 | inferred from electronic annotation with InterPro:IPR004640 chaperone binding ; GO:0051087 | inferred from electronic annotation with InterPro:IPR004640 molecular_function ; GO:0003674 | no biological data available protein maturation by iron-sulfur cluster transfer ; GO:0097428 | inferred from electronic annotation with InterPro:IPR004640 protein oligomerization ; GO:0051259 | inferred from electronic annotation with InterPro:IPR009073 biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from direct assay "CG34246, Hsc20, l(3)72Do" "IPR009073:Co-chaperone HscB, C-terminal oligomerisation domain, IPR001623:DnaJ domain, IPR004640:Co-chaperone Hsc20" CG34246 11-Aug-17 DroID_v2017_08 Drer\si:ch211-207k7.4 Scer\JAC1 Cele\dnj-15 Xtro\hscb Mmus\Hscb Hsap\HSCB FBgn0259583 B2029 - http://flybase.org/reports/FBgn0259583 gene - - - B2029 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible leg FBgn0052724 CR32724 - http://flybase.org/reports/FBgn0052724 non_protein_coding_gene - - - CR32724 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004739 l(3)85Df lethal (3) 85Df http://flybase.org/reports/FBgn0004739 - gene - - - l(3)85Df - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014205 l(1)16Fl lethal (1) 16Fl http://flybase.org/reports/FBgn0014205 - gene - - - l(1)16Fl - - 11-Aug-17 DroID_v2017_08 - - - - - - "hypoactive,visible,lethal - all die before end of pupal stage,recessive,some die during pupal stage" macrochaeta FBgn0024232 gprs gprs http://flybase.org/reports/FBgn0024232 FBgn0042196 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - "Gprs, CG5967, CG18471, gprs" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR011705:BTB/Kelch-associated" CG18471 11-Aug-17 DroID_v2017_08 "Drer\enc3, Drer\klhl25, Drer\enc1" - - - "Mmus\Klhl25, Mmus\Enc1" "Hsap\ENC1, Hsap\KLHL25" viable FBgn0013555 l(3)ry141 lethal (3) ry141 http://flybase.org/reports/FBgn0013555 - gene - - - "l(3)141, l(3)ry141" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0054051 CG34051 - http://flybase.org/reports/FBgn0054051 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "BP1077, HDC03337, CG34051" - CG34051 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034564 CG9344 - http://flybase.org/reports/FBgn0034564 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:17017 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002786" small nucleolar ribonucleoprotein complex ; GO:0005732 | inferred from electronic annotation with InterPro:IPR016487 U6 snRNP ; GO:0005688 | non-traceable author statement spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000002786 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000002786 "BcDNA:RE43665, CG9344" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR016487:Sm-like protein Lsm6/SmF" CG9344 11-Aug-17 DroID_v2017_08 "Drer\lsm6, Drer\snrpf" "Scer\LSM6, Scer\SMX3" "Cele\snr-5, Cele\lsm-6" "Xtro\lsm6, Xtro\snrpf" "Mmus\Snrpf, Mmus\Lsm6" Hsap\LSM6 "lethal,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval brain FBgn0265712 CR44519 - http://flybase.org/reports/FBgn0265712 non_protein_coding_gene - - - CR44519 - CR44519 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019684 mle::z mle::z http://flybase.org/reports/FBgn0019684 - engineered_fusion_gene - - - mle::z - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010178 tu(2)2 tu(2)2 http://flybase.org/reports/FBgn0010178 - gene - - - tu(2)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,partially lethal - majority die" FBgn0013554 l(3)ry133 lethal (3) ry133 http://flybase.org/reports/FBgn0013554 - gene - - - "l(3)133, l(3)ry133" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034962 MAN1 MAN1 http://flybase.org/reports/FBgn0034962 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 negative regulation of BMP signaling pathway ; GO:0030514 | inferred from direct assay integral component of nuclear inner membrane ; GO:0005639 | inferred from electronic annotation with InterPro:IPR018996 endomembrane system ; GO:0012505 | inferred from direct assay "CG3167, dMAN1, BcDNA:LD24895, MAN1, dMan1" "IPR003887:LEM domain, IPR011015:LEM/LEM-like domain, IPR000504:RNA recognition motif domain, IPR034394:MAN1, RNA recognition motif, IPR018996:Inner nuclear membrane protein MAN1" CG3167 11-Aug-17 DroID_v2017_08 "Drer\rbm39a, Drer\lemd3, Drer\rbm39b" - Cele\lem-2 "Xtro\lemd3, Xtro\rbm39, Xtro\rbm23" "Mmus\Lemd2, Mmus\Lemd3, Mmus\Rbm39" "Hsap\RBM39, Hsap\LEMD3, Hsap\LEMD2, Hsap\RBM23" "short lived,male sterile,female semi-sterile,flightless,neuroanatomy defective,locomotor rhythm defective,neurophysiology defective,partially lethal - majority die,some die during pharate adult stage,viable,fertile,lethal,recessive,rescuable maternal effect,visible,locomotor behavior defective,female sterile,partially,some die during pupal stage" "wing vein,ectopic,posterior crossvein,anterior crossvein,wing vein L4,wing blade,wing,testis,ovary" FBgn0054029 CG34029 - http://flybase.org/reports/FBgn0054029 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1066, CG34029" - CG34029 11-Aug-17 DroID_v2017_08 Drer\fam76b - - - - - FBgn0045468 Gr93d Gustatory receptor 93d http://flybase.org/reports/FBgn0045468 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "DmGr93d, Gr93F4, 93F.4, GR93F.4, CG31335, Gr93d, GR93d" IPR013604:7TM chemoreceptor CG31335 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - viable embryonic/larval hemocyte | third instar larval stage FBgn0001023 fs(3)A14 female sterile (3) A14 http://flybase.org/reports/FBgn0001023 - gene - - - fs(3)A14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0264484 CR43892 - http://flybase.org/reports/FBgn0264484 non_protein_coding_gene - - - CR43892 - CR43892 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085210 CG34181 - http://flybase.org/reports/FBgn0085210 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34181 IPR032145:Protein of unknown function DUF4818 CG34181 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263480 snoRNA:Irbp-a - http://flybase.org/reports/FBgn0263480 snoRNA_gene - - - "snoRNA:Irbp-a, snoRNA:irbp-a" - CR43595 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267454 CR45804 - http://flybase.org/reports/FBgn0267454 non_protein_coding_gene - - - CR45804 - CR45804 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030552 mRpL38 mitochondrial ribosomal protein L38 http://flybase.org/reports/FBgn0030552 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AI074410 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AI074410 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AI074410 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "MRP-L3, CG15871, mRpL3a, mRpL38" IPR008914:Phosphatidylethanolamine-binding protein CG15871 11-Aug-17 DroID_v2017_08 "Drer\mrpl38, Drer\pebp1" "Scer\YLR179C, Scer\TFS1, Scer\MRPL35" "Cele\C56G2.4, Cele\mrpl-38" "Xtro\pebp4, Xtro\pebp1, Xtro\mrpl38" "Mmus\Pbp2, Mmus\Pebp4, Mmus\Mrpl38, Mmus\Pebp1" "Hsap\PEBP4, Hsap\MRPL38, Hsap\PEBP1" "viable,visible" trichogen cell FBgn0033762 ZnT49B Zinc transporter 49B http://flybase.org/reports/FBgn0033762 protein_coding_gene cation transmembrane transporter activity ; GO:0008324 | inferred from electronic annotation with InterPro:IPR002524 cation transport ; GO:0006812 | inferred from electronic annotation with InterPro:IPR002524 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002524 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002524 "CG8632, ZnT49B, dZnT49B, cg8632" "IPR022656:XPA C- terminal, IPR002524:Cation efflux protein, IPR009061:Putative DNA-binding domain" CG8632 11-Aug-17 DroID_v2017_08 Drer\slc30a9 "Scer\MMT1, Scer\MMT2" Cele\Y71H2AM.9 Xtro\slc30a9 Mmus\Slc30a9 Hsap\SLC30A9 "viable,visible" trichogen cell FBgn0031459 CG2862 - http://flybase.org/reports/FBgn0031459 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011146 - - CG2862 "IPR001310:Histidine triad (HIT) protein, IPR011146:HIT-like domain, IPR019808:Histidine triad, conserved site" CG2862 11-Aug-17 DroID_v2017_08 "Drer\hint2, Drer\hint1" Scer\HNT1 Cele\hint-1 "Xtro\hint1, Xtro\hint2" "Mmus\Hint1, Mmus\Hint2" "Hsap\HINT2, Hsap\HINT1" DRSC26502 K 0.314245589 -0.868546306 -0.34541095 -0.323914662 0.050671809 -1.944829843 FBgn0028384 cof condensed figures http://flybase.org/reports/FBgn0028384 gene - - - cof - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036888 CG9330 - http://flybase.org/reports/FBgn0036888 protein_coding_gene "ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871" - - CG9330 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR032781:ABC-transporter extension domain" CG9330 11-Aug-17 DroID_v2017_08 "Drer\abcf2b, Drer\abcf3, Drer\abcf2a, Drer\abcf1" "Scer\GCN20, Scer\ARB1" Cele\abcf-3 "Xtro\abcf3, Xtro\abcf1" "Mmus\Abcf3, Mmus\Abcf2" "Hsap\ABCF3, Hsap\ABCF2" "viable,fertile,visible" trichogen cell FBgn0035960 CG4942 - http://flybase.org/reports/FBgn0035960 protein_coding_gene - protein insertion into membrane ; GO:0051205 | inferred from electronic annotation with InterPro:IPR001708 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001708 CG4942 IPR001708:Membrane insertase OXA1/ALB3/YidC CG4942 11-Aug-17 DroID_v2017_08 "Drer\cox18, Drer\oxa1l, Drer\si:dkey-91i10.3, Drer\si:ch211-113j14.1" "Scer\COX18, Scer\OXA1" "Cele\oxa-1, Cele\Y55F3AR.1" "Xtro\cox18, Xtro\oxa1l" "Mmus\Oxa1l, Mmus\Cox18" "Hsap\COX18, Hsap\OXA1L" viable FBgn0011276 HLH3B Helix loop helix protein 3B http://flybase.org/reports/FBgn0011276 - protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001015390 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001015390" - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001015390 "HLH3b, EG:155E2.2, CG2655, DroSCL, HLH3B, bHLHa20" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG2655 11-Aug-17 DroID_v2017_08 "Drer\ascl1b, Drer\nhlh2, Drer\tcf23, Drer\si:ch211-246m6.4, Drer\figla, Drer\tcf21, Drer\ptf1a, Drer\hand2, Drer\msc, Drer\scxa, Drer\scxb, Drer\mespba, Drer\mespaa, Drer\msgn1, Drer\tcf15, Drer\tcf24, Drer\mespab, Drer\ascl1a, Drer\lyl1, Drer\tal2, Drer\tal1" - - "Xtro\nhlh1, Xtro\figla, Xtro\hand2, Xtro\tal1, Xtro\lyl1, Xtro\hand1, Xtro\msgn1, Xtro\scx, Xtro\ascl2, Xtro\msc, Xtro\ptf1a, Xtro\mespb, Xtro\mespa, Xtro\tcf21, Xtro\ascl3, Xtro\tcf15" "Mmus\Nhlh1, Mmus\Tal1, Mmus\Ferd3l, Mmus\Tcf15, Mmus\Msgn1, Mmus\Tcf23, Mmus\Ascl4, Mmus\Ascl1, Mmus\Tal2, Mmus\Mesp1, Mmus\Ptf1a, Mmus\Mesp2, Mmus\Tcf21, Mmus\Figla, Mmus\Ascl3, Mmus\Hand1, Mmus\Nhlh2, Mmus\Hand2, Mmus\Scx, Mmus\Lyl1, Mmus\Ascl5, Mmus\Msc" "Hsap\ASCL4, Hsap\TAL2, Hsap\FIGLA, Hsap\TCF23, Hsap\HAND1, Hsap\MESP1, Hsap\TCF21, Hsap\ASCL1, Hsap\MSC, Hsap\LYL1, Hsap\MSGN1, Hsap\ASCL5, Hsap\NHLH1, Hsap\NHLH2, Hsap\MESP2, Hsap\ASCL3, Hsap\PTF1A, Hsap\HAND2, Hsap\TCF15, Hsap\TCF24, Hsap\SCX, Hsap\TAL1" " pupal stage , embryonic stage | stage >=8 " ventral midline

viable FBgn0046631 anon-38E.5 anon-38E.5 http://flybase.org/reports/FBgn0046631 gene - - - "38E.5, anon-38E.5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022750 anon-D2b anon-D2b http://flybase.org/reports/FBgn0022750 - gene - - - "D2, anon-D2b" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003166 pun puny http://flybase.org/reports/FBgn0003166 - gene - - - pun - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,female fertile,viable,reduced,visible,recessive" "wing,eye" FBgn0038038 CG5167 - http://flybase.org/reports/FBgn0038038 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005097 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005097 lipid particle ; GO:0005811 | inferred from direct assay CG5167 "IPR005097:Saccharopine dehydrogenase, NADP binding domain, IPR016040:NAD(P)-binding domain" CG5167 11-Aug-17 DroID_v2017_08 "Drer\zgc:174379, Drer\sccpdhb, Drer\ruvbl1, Drer\ruvbl2, Drer\sccpdha" - "Cele\ruvb-1, Cele\ruvb-2, Cele\ldp-1, Cele\Y50D4B.2, Cele\F22F7.2" "Xtro\LOC100490002, Xtro\sccpdh, Xtro\ruvbl1, Xtro\ruvbl2" "Mmus\Sccpdh, Mmus\Ruvbl2, Mmus\Ruvbl1" "Hsap\RUVBL1, Hsap\SCCPDH, Hsap\RUVBL2" viable FBgn0034156 CG5348 - http://flybase.org/reports/FBgn0034156 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004837 CG5348 IPR004837:Sodium/calcium exchanger membrane region CG5348 11-Aug-17 DroID_v2017_08 Drer\slc8b1 "Scer\ECM27, Scer\YDL206W" "Cele\ncx-6, Cele\ncx-8, Cele\ncx-9, Cele\ncx-7, Cele\ncx-10" Xtro\slc8b1 Mmus\Slc8b1 Hsap\SLC8B1 "viable,visible" trichogen cell FBgn0060808 l(3)S054910b lethal (3) S054910b http://flybase.org/reports/FBgn0060808 gene - - - "0549/10, l(3)S054910b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266351 CR45000 - http://flybase.org/reports/FBgn0266351 non_protein_coding_gene - - - CR45000 - CR45000 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065503 l(2)SH1202 lethal (2) SH1202 http://flybase.org/reports/FBgn0065503 gene - - - "l(2)SH1202, l(2)SH2 1202" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260343 GSd247 - http://flybase.org/reports/FBgn0260343 gene - - - GSd247 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0267573 CR45913 - http://flybase.org/reports/FBgn0267573 non_protein_coding_gene - - - "CR45913, pri-mir-1002_mir-968" - CR45913 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039937 fd102C forkhead domain 102C http://flybase.org/reports/FBgn0039937 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "Dmcg11152, fd102C, CG11152" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR018122:Fork head domain conserved site1, IPR030456:Fork head domain conserved site 2" CG11152 11-Aug-17 DroID_v2017_08 "Drer\foxd3, Drer\foxq2, Drer\foxd2, Drer\foxb2, Drer\foxb1b, Drer\foxk2, Drer\foxk1, Drer\foxj1a, Drer\foxb1a, Drer\foxg1a, Drer\si:ch211-262e15.1, Drer\foxl1" "Scer\FKH2, Scer\FKH1, Scer\HCM1, Scer\FHL1" "Cele\lin-31, Cele\fkh-9, Cele\fkh-10, Cele\fkh-2, Cele\unc-130" "Xtro\foxb1, Xtro\foxd2, Xtro\foxk2, Xtro\foxi4.2, Xtro\foxd4l1.1, Xtro\foxj1.2, Xtro\foxd3, Xtro\foxj1" "Mmus\Foxb1, Mmus\Foxj1, Mmus\Foxg1, Mmus\Foxl1, Mmus\Foxb2, Mmus\Foxd3, Mmus\Foxk1, Mmus\Foxk2, Mmus\Foxl2" "Hsap\FOXD4, Hsap\FOXK2, Hsap\FOXJ1, Hsap\FOXL2, Hsap\FOXD3, Hsap\FOXG1, Hsap\FOXB2, Hsap\FOXB1, Hsap\FOXL1, Hsap\FOXK1, Hsap\FOXS1" FBgn0002933 ng1 new glue 1 http://flybase.org/reports/FBgn0002933 FBgn0010372 protein_coding_gene - - - "ng-1, ng, ngp, SC1, EG:96G10.5, CG10781, ng1" - CG10781 11-Aug-17 DroID_v2017_08 - - - - - - larval stage | third instar FBgn0053129 CG33129 - http://flybase.org/reports/FBgn0053129 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to hyperoxia ; GO:0055093 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG6089, CG6087, CG33129" "IPR019308:Transmembrane protein 214, IPR016024:Armadillo-type fold" CG33129 11-Aug-17 DroID_v2017_08 Drer\tmem214 - - - Mmus\Tmem214 Hsap\TMEM214 "viable,fertile" FBgn0002691 mc microchaetae http://flybase.org/reports/FBgn0002691 - gene - - - "mc-like, tb-53, mc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile" "microchaeta & adult thorax,macrochaeta,scutellum & macrochaeta,eye,wing,tergite,female,microchaeta,scutellar bristle,head bristle,wing margin bristle,adult abdomen & sclerite" FBgn0260768 CG42566 - http://flybase.org/reports/FBgn0260768 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13512, CG42566" IPR006629:LPS-induced tumour necrosis factor alpha factor CG42566 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-202h22.7, Drer\si:dkeyp-75b4.8, Drer\si:ch211-157c3.4, Drer\cdip1, Drer\si:ch211-202h22.8, Drer\litaf, Drer\si:ch211-202h22.9" - "Cele\F36G3.3, Cele\F16F9.1, Cele\Y40H7A.11, Cele\B0348.1, Cele\Y37D8A.26, Cele\Y87G2A.18, Cele\Y22D7AL.15, Cele\B0348.2, Cele\Y37D8A.6, Cele\C08E8.1, Cele\Y87G2A.19, Cele\Y37D8A.8" - "Mmus\Cdip1, Mmus\Litaf" "Hsap\LITAF, Hsap\CDIP1" FBgn0037734 trbd trabid http://flybase.org/reports/FBgn0037734 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P91667 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from biological aspect of ancestor with PANTHER:PTN001001090 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:18224 K63-linked polyubiquitin binding ; GO:0070530 | inferred from biological aspect of ancestor with PANTHER:PTN001001090 cell migration ; GO:0016477 | inferred from biological aspect of ancestor with PANTHER:PTN000332188 protein K33-linked deubiquitination ; GO:1990168 | inferred from biological aspect of ancestor with PANTHER:PTN000332188 protein K29-linked deubiquitination ; GO:0035523 | inferred from biological aspect of ancestor with PANTHER:PTN000332188 protein K63-linked deubiquitination ; GO:0070536 | inferred from sequence or structural similarity with UniProtKB:Q9UGI0 protein deubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0071947 | inferred from biological aspect of ancestor with PANTHER:PTN001001090 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype inferred from genetic interaction with arm inferred from genetic interaction with wg protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:18224 cytoskeleton organization ; GO:0007010 | inferred from biological aspect of ancestor with PANTHER:PTN000332188 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001001090 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:18224 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001001090 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:18224 "CG9448, trbd, Q9VH90, Trbd" "IPR001876:Zinc finger, RanBP2-type, IPR003323:OTU domain" CG9448 11-Aug-17 DroID_v2017_08 "Drer\zranb1b, Drer\otud7b, Drer\zranb1a" - Cele\otub-2 Xtro\zranb1 "Mmus\Otud7b, Mmus\Zranb1" "Hsap\OTUD7B, Hsap\OTUD7A, Hsap\ZRANB1" "viable,fertile,locomotor behavior defective,short lived" heart primordium FBgn0262550 Mod(GMroX1)8 - http://flybase.org/reports/FBgn0262550 gene - - - Mod(GMroX1)8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259434 EP-158 - http://flybase.org/reports/FBgn0259434 gene - - - EP-158 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0044322 jockey\ORF jockey element ORF http://flybase.org/reports/FBgn0044322 transposable_element_gene - - - "D-element\ORF, jockey\ORF" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001873 l(1)XN75a lethal (1) XN75a http://flybase.org/reports/FBgn0001873 - gene - - - l(1)XN75a - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265738 CR44545 - http://flybase.org/reports/FBgn0265738 non_protein_coding_gene - - - "CR44545, incRNA.496, lincRNA.496" - CR44545 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052056 scramb1 scramblase 1 http://flybase.org/reports/FBgn0052056 protein_coding_gene phospholipid scramblase activity ; GO:0017128 | inferred from biological aspect of ancestor with PANTHER:PTN000582979 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000582979 "CG6590, CT20492, scramb1, CG32056, Scramb1" "IPR025659:Tubby C-terminal-like domain, IPR005552:Scramblase" CG32056 11-Aug-17 DroID_v2017_08 "Drer\plscr3b, Drer\si:ch211-71m22.5, Drer\si:ch73-206p6.1, Drer\LOC100537119, Drer\si:dkey-62k3.6, Drer\plscr3a, Drer\si:ch211-71m22.3, Drer\LOC100536708, Drer\si:ch211-71m22.1" Scer\AIM25 "Cele\ZC53.4, Cele\K08D10.18, Cele\scrm-1, Cele\scrm-5, Cele\scrm-2, Cele\scrm-4, Cele\scrm-3, Cele\scrm-8, Cele\scrm-7, Cele\C33E10.6, Cele\scrm-6" "Xtro\plscr3, Xtro\plscr2, Xtro\plscr1" "Mmus\Plscr3, Mmus\Plscr4, Mmus\1700057G04Rik, Mmus\Plscr1, Mmus\Plscr2, Mmus\Plscr5" "Hsap\PLSCR5, Hsap\PLSCR2, Hsap\PLSCR4, Hsap\PLSCR1, Hsap\PLSCR3" "viable,fertile" DRSC09724 K 0.108980203 -0.493186742 -0.043814901 -0.104756792 -0.019891358 -1.683817184 FBgn0002808 ms(1)401 male sterile (1) 401 http://flybase.org/reports/FBgn0002808 - gene - - - ms(1)401 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" "spermatocyte & nucleus,spermatocyte & nucleolus,Y chromosome loop" FBgn0052827 CG32827 - http://flybase.org/reports/FBgn0052827 protein_coding_gene - - - CG32827 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019738 l(1)91-3 lethal (1) 91-3 http://flybase.org/reports/FBgn0019738 - gene - - - l(1)91-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266172 pre-mod(mdg4)-E - http://flybase.org/reports/FBgn0266172 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-E, CG44878" - CG44878 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Flywch1, Mmus\Flywch2" - FBgn0038675 CG6013 - http://flybase.org/reports/FBgn0038675 protein_coding_gene - - - CG6013 "IPR009071:High mobility group box domain, IPR010422:Coiled-coil domain-containing protein 124" CG6013 11-Aug-17 DroID_v2017_08 Drer\ccdc124 Scer\LSO1 Cele\Y73E7A.1 Xtro\ccdc124 Mmus\Ccdc124 Hsap\CCDC124 viable FBgn0038080 CG12279 - http://flybase.org/reports/FBgn0038080 protein_coding_gene thiosulfate sulfurtransferase activity ; GO:0004792 | inferred from electronic annotation with InterPro:IPR001307 - - "BcDNA:RH54517, CG12279" "IPR001307:Thiosulphate sulfurtransferase, conserved site, IPR001763:Rhodanese-like domain" CG12279 11-Aug-17 DroID_v2017_08 "Drer\LOC561325, Drer\si:dkey-22i16.9, Drer\si:ch211-161h7.8, Drer\si:dkey-34l15.1, Drer\si:dkey-165n16.1" "Scer\RDL1, Scer\RDL2" - "Xtro\tstd3, Xtro\LOC100485051" "Mmus\Tstd1, Mmus\Tstd3" "Hsap\TSTD3, Hsap\TSTD1" "viable,fertile" FBgn0021852 l(2)k14601 lethal (2) k14601 http://flybase.org/reports/FBgn0021852 - gene - - - l(2)k14601 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051068 CG31068 - http://flybase.org/reports/FBgn0051068 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "BcDNA:AT10318, CG31068" - CG31068 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0039508 CG3368 - http://flybase.org/reports/FBgn0039508 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3368, SD09067p" "IPR016024:Armadillo-type fold, IPR019442:Domain of unknown function DUF2428, death-receptor-like" CG3368 11-Aug-17 DroID_v2017_08 Drer\thada Scer\TRM732 Cele\Y92H12A.5 - Mmus\Thada Hsap\THADA viable embryonic/larval hemocyte | third instar larval stage DRSC15485 K 0.486685737 -0.08246026 0.329580723 0.370907528 1.658436237 -0.150253754 FBgn0085600 CG41286 - http://flybase.org/reports/FBgn0085600 protein_coding_gene - - - CG41286 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035570 CG13712 - http://flybase.org/reports/FBgn0035570 protein_coding_gene - regulation of localization ; GO:0032879 | inferred from sequence or structural similarity with halo - "HL4, CG13712" IPR007970:Protein of unknown function DUF733 CG13712 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | embryonic cycle 14 blastoderm embryo | striped

viable FBgn0061031 l(3)S024421 lethal (3) S024421 http://flybase.org/reports/FBgn0061031 gene - - - "0244/21, l(3)S024421" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267205 CR45645 - http://flybase.org/reports/FBgn0267205 non_protein_coding_gene - - - CR45645 - CR45645 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084024 CG41463 - http://flybase.org/reports/FBgn0084024 protein_coding_gene - - - CG41463 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263256 CG43394 - http://flybase.org/reports/FBgn0263256 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43394, BcDNA:RE27850, CG31607, CG31900" IPR013783:Immunoglobulin-like fold CG43394 11-Aug-17 DroID_v2017_08 "Drer\wu:fa25f02, Drer\mansc1" - - - "Mmus\1810055G02Rik, Mmus\Mansc4, Mmus\Mansc1" "Hsap\MANSC4, Hsap\MANSC1, Hsap\C11orf24" DRSC01013 E -1.151415306 -0.448441508 2.779887731 0.921811947 -1.279607288 0.043368998 FBgn0259659 B0183 - http://flybase.org/reports/FBgn0259659 gene - - - B0183 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "leg,unguis,arista" FBgn0002341 l(3)87Bj lethal (3) 87Bj http://flybase.org/reports/FBgn0002341 - gene - - - "ck22, l(3)ck22, l(3)87Bj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0261006 snoRNA:83E4-5 - http://flybase.org/reports/FBgn0261006 snoRNA_gene - - - "snoRNA:83E4-5, Dm83E4-5" - CR43568 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033088 PGAP3 Post-GPI attachment to proteins 3 http://flybase.org/reports/FBgn0033088 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from sequence or structural similarity with HGNC:23719 hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from sequence or structural similarity with UniProtKB:Q96FM1" GPI anchor metabolic process ; GO:0006505 | inferred from sequence or structural similarity with HGNC:23719 GPI anchor metabolic process ; GO:0006505 | inferred from sequence or structural similarity with UniProtKB:Q96FM1 intrinsic component of endoplasmic reticulum membrane ; GO:0031227 | inferred from sequence or structural similarity with HGNC:23719 intrinsic component of endoplasmic reticulum membrane ; GO:0031227 | inferred from sequence or structural similarity with UniProtKB:Q96FM1 "PGAP3, CG3271" IPR007217:Per1-like CG3271 11-Aug-17 DroID_v2017_08 Drer\pgap3 Scer\PER1 Cele\R01B10.4 Xtro\pgap3 Mmus\Pgap3 Hsap\PGAP3 "viable,partially lethal - majority die,some die during pupal stage" FBgn0062568 Mod(var)E226 Mod(var)E226 http://flybase.org/reports/FBgn0062568 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E226, Mod(var)E226" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0065919 l(2)SH0159 lethal (2) SH0159 http://flybase.org/reports/FBgn0065919 gene - - - "l(2)SH0159, l(2)SH2 0159" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011257 ms(2)43C male sterile (2)43C http://flybase.org/reports/FBgn0011257 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - ms(2)43C - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "spermatid,Nebenkern" FBgn0044334 682 682 http://flybase.org/reports/FBgn0044334 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available 682 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264087 Slob Slowpoke binding protein http://flybase.org/reports/FBgn0264087 protein_coding_gene protein kinase activity ; GO:0004672 | NOT inferred from key residues protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P29310 protein kinase activity ; GO:0004672 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q03720 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | NOT inferred from key residues modulation of synaptic transmission ; GO:0050804 | non-traceable author statement neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype regulation of membrane potential ; GO:0042391 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype cytoplasm ; GO:0005737 | non-traceable author statement "CG43756, slob, Slob, CG6772, CG13792" IPR011009:Protein kinase-like domain CG43756 11-Aug-17 DroID_v2017_08 Drer\pxk - - Xtro\pxk Mmus\Pxk Hsap\PXK FBgn0038239 CG14850 - http://flybase.org/reports/FBgn0038239 protein_coding_gene - - - CG14850 - CG14850 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002934 ni-B nicked of Bridges http://flybase.org/reports/FBgn0002934 - gene - - - "ni-2, ni-B, ni" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0067343 l(3)L3D lethal (3) L3D http://flybase.org/reports/FBgn0067343 gene - - - l(3)L3D - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0266318 CR44983 - http://flybase.org/reports/FBgn0266318 non_protein_coding_gene - - - CR44983 - CR44983 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033179 p47 p47 http://flybase.org/reports/FBgn0033179 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000596256 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000596256 membrane fusion ; GO:0061025 | inferred from biological aspect of ancestor with PANTHER:PTN000596257 rhabdomere development ; GO:0042052 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000596257 nuclear envelope reassembly ; GO:0031468 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000596257 cytoplasm ; GO:0005737 | inferred from direct assay "CG11139, dp47, anon-WO0118547.216, p47" "IPR001012:UBX domain, IPR009060:UBA-like, IPR012989:SEP domain, IPR029071:Ubiquitin-related domain" CG11139 11-Aug-17 DroID_v2017_08 "Drer\nsfl1c, Drer\ubxn2a, Drer\ubxn11" Scer\SHP1 Cele\ubxn-2 "Xtro\ubxn11, Xtro\ubxn2a" "Mmus\Ubxn2a, Mmus\Nsfl1c, Mmus\Ubxn2b, Mmus\Ubxn11" "Hsap\UBXN11, Hsap\UBXN2B, Hsap\UBXN2A, Hsap\NSFL1C" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0265885 CR44674 - http://flybase.org/reports/FBgn0265885 non_protein_coding_gene - - - "CR44674, lincRNA.613" - CR44674 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044515 l(2)Jan344 lethal (2) Jan344 http://flybase.org/reports/FBgn0044515 gene - - - l(2)Jan344 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030734 CG9911 - http://flybase.org/reports/FBgn0030734 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 "LD41494p, CG9912, CG9911" "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain" CG9911 11-Aug-17 DroID_v2017_08 Drer\erp44 "Scer\MPD1, Scer\EPS1, Scer\EUG1, Scer\PDI1" "Cele\F42G8.7, Cele\C06A6.5, Cele\C30H7.2" Xtro\erp44 Mmus\Erp44 Hsap\ERP44 "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0037759 CG8526 - http://flybase.org/reports/FBgn0037759 protein_coding_gene asparaginase activity ; GO:0004067 | inferred from biological aspect of ancestor with PANTHER:PTN000194585 asparagine catabolic process ; GO:0006530 | inferred from biological aspect of ancestor with PANTHER:PTN000194585 - CG8526 "IPR002110:Ankyrin repeat, IPR006033:L-asparaginase, type I, IPR006034:Asparaginase/glutaminase, IPR027474:L-asparaginase, N-terminal, IPR027473:L-asparaginase, C-terminal domain, IPR027475:Asparaginase/glutaminase, active site 2, IPR020683:Ankyrin repeat-containing domain" CG8526 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-209a2.2, Drer\si:dkey-74k8.4, Drer\aspg, Drer\si:dkey-9i23.14" "Scer\ASP3-3, Scer\SOK2, Scer\YGP1, Scer\PHD1, Scer\ASP3-4, Scer\SPS100, Scer\ASP3-2, Scer\ASP1, Scer\ASP3-1" Cele\C27A7.5 Xtro\aspg "Mmus\Ankrd22, Mmus\Aspg" Hsap\ASPG FBgn0267621 CR45959 - http://flybase.org/reports/FBgn0267621 non_protein_coding_gene - - - CR45959 - CR45959 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065533 l(2)SH1104 lethal (2) SH1104 http://flybase.org/reports/FBgn0065533 gene - - - "l(2)SH1104, l(2)SH2 1104" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000924 fs(1)ne12 female sterile (1) no eggs 12 http://flybase.org/reports/FBgn0000924 - gene - - - "ne12, fs(1)ne[12], fs(1)ne12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "endochorion,dorsal appendage,chorion" FBgn0011098 l(1)Q58 lethal (1) Q58 http://flybase.org/reports/FBgn0011098 FBgn0010210 gene - - - l(1)Q58 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0027569 cert ceramide transfer protein http://flybase.org/reports/FBgn0027569 - protein_coding_gene ceramide binding ; GO:0097001 | inferred from direct assay ceramide transporter activity ; GO:0035620 | inferred from direct assay phosphatidylinositol-4-phosphate binding ; GO:0070273 | inferred from sequence or structural similarity with HGNC:2205 ER to Golgi ceramide transport ; GO:0035621 | inferred from sequence or structural similarity with HGNC:2205 sphingolipid metabolic process ; GO:0006665 | inferred from mutant phenotype ceramide transport ; GO:0035627 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "BcDNA:GH07688, Dcert, dcert, cert, CERT, CG7207" "IPR001849:Pleckstrin homology domain, IPR002913:START domain, IPR011993:PH domain-like, IPR023393:START-like domain" CG7207 11-Aug-17 DroID_v2017_08 "Drer\plekha3, Drer\plekha8, Drer\col4a3bpb, Drer\col4a3bpa" Scer\SWH1 Cele\F25H2.6 "Xtro\osbpl11, Xtro\col4a3bp, Xtro\plekha3, Xtro\plekha8" "Mmus\Col4a3bp, Mmus\Plekha3, Mmus\Plekha8" "Hsap\PLEKHA8, Hsap\PLEKHA3, Hsap\COL4A3BP" "viable,fertile,short lived,locomotor behavior defective,heat stress response defective,stress response defective" plasma membrane FBgn0010092 Su(vg)E4 Suppressor of vestigial E4 http://flybase.org/reports/FBgn0010092 - gene - - - "vg[[EMS4]], Su(vg)E4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040507 ACXD ACXD http://flybase.org/reports/FBgn0040507 protein_coding_gene guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 adenylate cyclase activity ; GO:0004016 | inferred from sequence model adenylate cyclase activity ; GO:0004016 | non-traceable author statement "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "integral component of membrane ; GO:0016021 | inferred from sequence model guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924" "CG5712, AC, DACXD, ACXD" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase, IPR032628:Adenylate cyclase, N-terminal" CG5712 11-Aug-17 DroID_v2017_08 "Drer\adcy1a, Drer\adcy8, Drer\adcy1b, Drer\adcy6a, Drer\adcy5, Drer\adcy3a, Drer\adcy7, Drer\adcy6b, Drer\adcy2a, Drer\adcy2b, Drer\si:ch211-132f19.7, Drer\si:dkey-206f10.1" - "Cele\acy-1, Cele\acy-2, Cele\acy-4" "Xtro\dnajc27, Xtro\adcy1, Xtro\adcy4, Xtro\adcy7, Xtro\adcy6" "Mmus\Adcy4, Mmus\Adcy6, Mmus\Adcy7, Mmus\Adcy1, Mmus\Adcy8, Mmus\Adcy2, Mmus\Adcy3, Mmus\Adcy9, Mmus\Adcy5" "Hsap\ADCY8, Hsap\ADCY4, Hsap\ADCY1, Hsap\ADCY5, Hsap\ADCY9, Hsap\ADCY6, Hsap\ADCY3, Hsap\ADCY2, Hsap\ADCY7" " adult stage , embryonic stage | late , larval stage | late " FBgn0259859 Su(Ste):CR42428 Su(Ste):CR42428 http://flybase.org/reports/FBgn0259859 non_protein_coding_gene - - - "Su(Ste):CR42428, CR42428" - CR42428 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019746 l(1)83A lethal (1) 83A http://flybase.org/reports/FBgn0019746 - gene - - - l(1)83A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016723 Reg-9 Rhythmically expressed gene 9 http://flybase.org/reports/FBgn0016723 - gene - - - "Dreg-9, Reg-9" - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , embryonic stage | late " adult head

FBgn0021976 l(2)k09924 lethal (2) k09924 http://flybase.net/reports/FBgn0021976.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0264697 CR43966 - http://flybase.org/reports/FBgn0264697 non_protein_coding_gene - - - CR43966 - CR43966 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053536 tRNA:Leu-TAA-2-1 transfer RNA:Leucine-TAA 2-1 http://flybase.org/reports/FBgn0053536 tRNA_gene UUA codon-amino acid adaptor activity ; GO:0033403 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033403 cytosol ; GO:0005829 | inferred by curator from GO:0033403 "AE002708.trna28-LeuTAA, tRNA:L:TAA:AE002708-a, CR33536, chr3R.trna34-LeuTAA, tRNA-Leu-TAA-2-1, tRNA:Leu-TAA-2-1, tRNA:CR33536, UUA" - CR33536 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001410 l(1)3Bf lethal (1) 3Bf http://flybase.org/reports/FBgn0001410 - gene - - - "zw-11, zw11, l(1)zw11, ZW-11, l[a5], l(1)3Bf" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" "ovariole,germline clone,female reproductive system,egg" FBgn0053742 snmRNA:430:CR33742 snmRNA:430:CR33742 http://flybase.org/reports/FBgn0053742 non_protein_coding_gene - - - "CR33742, snmRNA:430:CR33742" - CR33742 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034330 CG18107 - http://flybase.org/reports/FBgn0034330 protein_coding_gene - - - "BcDNA:RH09147, CG18107" IPR013172:Immune-induced protein Dim CG18107 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035041 CG13594 - http://flybase.org/reports/FBgn0035041 protein_coding_gene - - - CG13594 IPR032061:Domain of unknown function DUF4802 CG13594 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011658 meringue meringue http://flybase.org/reports/FBgn0011658 - gene - - - meringue - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040941 CG15308 - http://flybase.org/reports/FBgn0040941 protein_coding_gene - - - CG15308 - CG15308 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0259559 GG01082 - http://flybase.org/reports/FBgn0259559 gene - - - GG01082 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "mediproboscis,wing" FBgn0003735 tov tiny ovaries http://flybase.org/reports/FBgn0003735 - gene - - - tov - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile ovary FBgn0036363 CG10140 - http://flybase.org/reports/FBgn0036363 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG10140 IPR002557:Chitin binding domain CG10140 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\R02F2.4, Cele\dct-9, Cele\cpg-2" - - Hsap\MATN2 viable FBgn0024617 ms59I-26A ms59I-26A http://flybase.org/reports/FBgn0024617 - gene - - - ms59I-26A - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,meiotic cell cycle defective,cytokinesis defective" FBgn0037937 Fer3 48 related 3 http://flybase.org/reports/FBgn0037937 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with twi" "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q923Z4 regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with twi" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q923Z4 "CG6913, nato3, Dnato3, BcDNA:LD04689, Fer3, bHLHa32" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG6913 11-Aug-17 DroID_v2017_08 "Drer\atoh1b, Drer\atoh7, Drer\atoh1c, Drer\ptf1a, Drer\atoh1a" - "Cele\hlh-6, Cele\hlh-13" "Xtro\ptf1a, Xtro\hand1, Xtro\atoh1, Xtro\atoh7, Xtro\ferd3l" "Mmus\Atoh7, Mmus\Atoh1, Mmus\Bhlha9, Mmus\Tal1, Mmus\Ferd3l, Mmus\Ptf1a" "Hsap\PTF1A, Hsap\BHLHA9, Hsap\FERD3L, Hsap\ATOH7, Hsap\TAL1, Hsap\ATOH1, Hsap\ASCL5, Hsap\ASCL3" " embryonic stage | stage 11-16 , embryonic stage | stage 13-16 " " ventral nerve cord primordium | segmentally repeated & restricted

, embryonic procephalic segment | restricted

" FBgn0060409 l(3)S130509 lethal (3) S130509 http://flybase.org/reports/FBgn0060409 gene - - - "1305/09, l(3)S130509" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0000807 Fs(2)G Female sterile of Grell http://flybase.org/reports/FBgn0000807 - gene - - - "Fs(2)D, Fs(2)G" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,dominant,male fertile,viable,reduced,heat sensitive,visible" "egg chamber,ovary,oviduct,oocyte,macrochaeta,wing,heat sensitive,adult thorax" FBgn0263208 CR43378 - http://flybase.org/reports/FBgn0263208 pseudogene_attribute - - - CR43378 - CR43378 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063549 Dm88\rt Dm88 element reverse transcriptase http://flybase.org/reports/FBgn0063549 transposable_element_gene - - - Dm88\rt "IPR013103:Reverse transcriptase, RNA-dependent DNA polymerase" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023106 anon-13Fb anon-13Fb http://flybase.org/reports/FBgn0023106 - gene - - - anon-13Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020584 anon-59Ca anon-59Ca http://flybase.org/reports/FBgn0020584 - gene - - - anon-59Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259942 Ttd7 TRPL translocation defect 7 http://flybase.org/reports/FBgn0259942 protein_coding_gene - - - Ttd7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261545 CG42663 - http://flybase.org/reports/FBgn0261545 protein_coding_gene - determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype - "CG42663, BcDNA:SD15892, CG12488, CG13486, CG18356" IPR026163:Nck-associated protein 5-like CG42663 11-Aug-17 DroID_v2017_08 Drer\nckap5l - - - "Mmus\Nckap5, Mmus\Nckap5l" "Hsap\NCKAP5L, Hsap\NCKAP5" """DRSC06158, DRSC06404"" " IEK FBgn0082191 l(3)Me10 lethal (3) Me10 http://flybase.org/reports/FBgn0082191 gene - - - l(3)Me10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,somatic clone,decreased cell size,decreased cell number,size defective,cell autonomous,cell non-autonomous,lethal - all die before end of embryonic stage,some die during embryonic stage" "chaeta,somatic clone,wing,adult abdomen,mesothoracic tergum,wing hair,microchaeta,macrochaeta" FBgn0010428 anon-61C anon-61C http://flybase.org/reports/FBgn0010428 FBgn0010430 repeat_region - - - anon-61C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038545 pasi1 pasiflora 1 http://flybase.org/reports/FBgn0038545 protein_coding_gene - "establishment of endothelial barrier ; GO:0061028 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from direct assay "dmCG7713, pasi1, CG7713" - CG7713 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040732 CG16926 - http://flybase.org/reports/FBgn0040732 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern - "CG16926, 141315_at" - CG16926 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001557 l(1)19Cb lethal (1) 19Cb http://flybase.org/reports/FBgn0001557 - gene - - - "16-398, l(1)19Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014923 anon-72ABg anon-72ABg http://flybase.org/reports/FBgn0014923 - gene - - - anon-72ABg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004231 l(3)93Be lethal (3) 93Be http://flybase.org/reports/FBgn0004231 - gene - - - "rlr3, l(3)93Be" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038458 VhaM9.7-d Vacuolar H[+] ATPase M9.7 subunit d http://flybase.org/reports/FBgn0038458 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from sequence model proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000262636" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model" "proton-transporting V-type ATPase, V0 domain ; GO:0033179 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from biological aspect of ancestor with PANTHER:PTN000262688" "VhaM9.7-d, vhaM9.7-4, CG14909, VhaM9.7-4" "IPR008389:ATPase, V0 complex, subunit e1/e2, IPR017385:ATPase, V0 complex, subunit e1/e2, metazoa" CG14909 11-Aug-17 DroID_v2017_08 "Drer\atp6v0e1, Drer\atpv0e2, Drer\pars2" Scer\VMA9 Cele\vha-17 "Xtro\atp6v0e2, Xtro\atp6v0e1" "Mmus\Atp6v0e, Mmus\Atp6v0e2, Mmus\Pars2" "Hsap\ATP6V0E2, Hsap\ATP6V0E1" "viable,visible" "chaeta,supernumerary" FBgn0002361 l(3)87Ei lethal (3) 87Ei http://flybase.org/reports/FBgn0002361 - gene - - - "S9, l(3)S9, l(3)s9, l(3)m102, l(3)87Ei" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264568 CR43940 - http://flybase.org/reports/FBgn0264568 non_protein_coding_gene - - - CR43940 - CR43940 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002015 l(2)36Fh lethal (2) 36Fh http://flybase.org/reports/FBgn0002015 - gene - - - "l(2)E50, l(2)36Fh" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0083307 E(smoDN)1485 Enhancer of smoDN 1485 http://flybase.org/reports/FBgn0083307 gene - - - E(smoDN)1485 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003197 rag ragged http://flybase.org/reports/FBgn0003197 - gene - - - rag - - 11-Aug-17 DroID_v2017_08 - - - - - - wing margin FBgn0016863 l(2)39ADa lethal (2) 39ADa http://flybase.org/reports/FBgn0016863 - gene - - - "B819, l(2)39ADa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040730 CG15127 - http://flybase.org/reports/FBgn0040730 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18365, CG15127" - CG15127 11-Aug-17 DroID_v2017_08 "Drer\plac8.2, Drer\ponzr10, Drer\LOC100537055" - - - Mmus\Plac8 Hsap\PLAC8 viable FBgn0259264 EP-689 - http://flybase.org/reports/FBgn0259264 gene - - - EP-689 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing hair FBgn0260368 GSd203 - http://flybase.org/reports/FBgn0260368 gene - - - GSd203 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001678 l(1)EN16 lethal (1) from Eugene Nonautonomous 16 http://flybase.org/reports/FBgn0001678 - gene - - - l(1)EN16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260322 GSd457 - http://flybase.org/reports/FBgn0260322 gene - - - GSd457 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053375 5SrRNA:CR33375 5SrRNA:CR33375 http://flybase.org/reports/FBgn0053375 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33375, 5SrRNA:CR33375" - CR33375 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002014 l(2)36Fg lethal (2) 36Fg http://flybase.org/reports/FBgn0002014 - gene - - - "l(2)E20, l(2)36Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002097 l(2)57Cc lethal (2) 57Cc http://flybase.org/reports/FBgn0002097 - gene - - - l(2)57Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260592 2L2475 - http://flybase.org/reports/FBgn0260592 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2475 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0044018 SY2-2 SY2-2 http://flybase.org/reports/FBgn0044018 gene - - - SY2-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038404 CG8925 - http://flybase.org/reports/FBgn0038404 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG8925 "IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8925 11-Aug-17 DroID_v2017_08 - "Scer\GIT1, Scer\HXT5, Scer\PHO84" "Cele\str-176, Cele\F32H5.4, Cele\oct-2, Cele\oat-1, Cele\F17C11.12" "Xtro\slc22a15.2, Xtro\slc22a15.1" "Mmus\Slc22a15, Mmus\Slc22a14" "Hsap\SLC22A14, Hsap\SLC22A15" viable FBgn0028232 l(3)S003704 lethal (3) S003704 http://flybase.org/reports/FBgn0028232 gene - - - "0037/04, l(3)S003704" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0040895 CG14773 - http://flybase.org/reports/FBgn0040895 protein_coding_gene - - - CG14773 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC17950 IE 0.733114108 1.531585814 8.741944617 -1.333350713 -1.299148299 -0.447122001 FBgn0016079 xerox xerox http://flybase.org/reports/FBgn0016079 - repeat_region - - - xerox - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262066 SG46 - http://flybase.org/reports/FBgn0262066 gene - - - SG46 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015761 Mei66F Meiotic 66F-67A http://flybase.org/reports/FBgn0015761 - gene - - - Mei66F - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027168 l(2)IH1 lethal (2) IH1 http://flybase.org/reports/FBgn0027168 - gene - - - l(2)IH1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011091 l(1)Q51 lethal (1) Q51 http://flybase.org/reports/FBgn0011091 FBgn0010210 gene - - - l(1)Q51 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267167 CR45607 - http://flybase.org/reports/FBgn0267167 non_protein_coding_gene - - - CR45607 - CR45607 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043865 SA-2 Stromalin-2 http://flybase.org/reports/FBgn0043865 protein_coding_gene - - nucleolus ; GO:0005730 | colocalizes_with inferred from direct assay condensed nuclear chromosome ; GO:0000794 | colocalizes_with inferred from direct assay "SNM, pf-1, CG1, CG13916, anon-WO0109301.35, SA-2, snm" "IPR013721:STAG, IPR016024:Armadillo-type fold, IPR020839:Stromalin conservative domain, IPR011989:Armadillo-like helical" CG13916 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-269e2.1, Drer\stag2b, Drer\stag1a, Drer\stag2a, Drer\stag1b" Scer\IRR1 Cele\scc-3 "Xtro\stag1, Xtro\stag3" "Mmus\Stag2, Mmus\Stag3, Mmus\Stag1" "Hsap\STAG1, Hsap\STAG2, Hsap\STAG3" meiotic cell cycle defective "meiosis I & nuclear chromosome,G2 phase & nuclear chromosome" FBgn0069213 hoernchen hoernchen http://flybase.org/reports/FBgn0069213 gene molecular_function ; GO:0003674 | no biological data available "maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available "hrn, hoernchen" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile,recessive,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect" FBgn0016896 l(3)64Cf lethal (3) 64Cf http://flybase.org/reports/FBgn0016896 - gene - - - l(3)64Cf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265623 Su(z)2 Suppressor of zeste 2 http://flybase.org/reports/FBgn0265623 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 DNA binding ; GO:0003677 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model chromatin silencing ; GO:0006342 | inferred from direct assay intercalary heterochromatin ; GO:0005725 | non-traceable author statement PRC1 complex ; GO:0035102 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG3905, Su(z)2, Su(z)2D, SUZ2, Su(z)[[2]], Arp, su(z)2, l(2)k06344, SU(Z)2, Su(z)3, su(z)3, Suz2, Su(Z)2" "IPR001841:Zinc finger, RING-type, IPR018957:Zinc finger, C3HC4 RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032443:RAWUL domain" CG3905 11-Aug-17 DroID_v2017_08 "Drer\pcgf5b, Drer\bmi1a, Drer\pcgf5a, Drer\pcgf6, Drer\bmi1b" - - "Xtro\pcgf3, Xtro\bmi1, Xtro\pcgf6, Xtro\pcgf2" "Mmus\Pcgf6, Mmus\Pcgf3, Mmus\Bmi1, Mmus\Pcgf2, Mmus\Pcgf1, Mmus\Pcgf5" "Hsap\PCGF6, Hsap\PCGF3, Hsap\PCGF1, Hsap\PCGF5, Hsap\BMI1, Hsap\COMMD3-BMI1, Hsap\PCGF2" FBgn0264545 CG43924 - http://flybase.org/reports/FBgn0264545 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43924 IPR031957:Domain of unknown function DUF4777 CG43924 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085648 CG41429 - http://flybase.org/reports/FBgn0085648 protein_coding_gene - - - CG41429 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028033 l(3)S101902 lethal (3) S101902 http://flybase.org/reports/FBgn0028033 gene - - - "1019/02, l(3)S101902" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060797 l(3)S057806 lethal (3) S057806 http://flybase.org/reports/FBgn0060797 gene - - - "0578/06, l(3)S057806" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011980 tRNA:Ser-AGA-3-1 transfer RNA:Serine-AGA 3-1 http://flybase.org/reports/FBgn0011980 "FBgn0003830, FBgn0011968, FBgn0052612, FBgn0060067" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "774-1, Ser-tRNA-4-7, AE002593.trna15-SerAGA, tRNA:S:AGA:AE002593-e, CR32612, tRNA:ser, tRNA:S, tRNA:ser774:12Ec, tRNA[[Ser]], chrX.trna24-SerAGA, tRNA-Ser-AGA-3-1, tRNA:Ser-AGA-3-1, tRNA:S774:12Ec, UCU" - CR32612 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264338 CR43794 - http://flybase.org/reports/FBgn0264338 non_protein_coding_gene - - - "CR43794, lincRNA.386" - CR43794 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031018 CG12200 - http://flybase.org/reports/FBgn0031018 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 SUMO transferase activity ; GO:0019789 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 zinc ion binding ; GO:0008270 | inferred from sequence model synapsis ; GO:0007129 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 protein sumoylation ; GO:0016925 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 synaptonemal complex ; GO:0000795 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 CG12200 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG12200 11-Aug-17 DroID_v2017_08 - Scer\CST9 "Cele\F55A12.10, Cele\D1081.9, Cele\Y39B6A.16, Cele\zhp-3, Cele\R06C7.2" - "Mmus\Rnf212b, Mmus\Rnf212" "Hsap\RNF212, Hsap\RNF212B" viable FBgn0062679 EP2086 EP2086 http://flybase.org/reports/FBgn0062679 gene - - - "EP(2)2086, EP2086" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028179 l(3)S024639b lethal (3) S024639b http://flybase.org/reports/FBgn0028179 gene - - - "0246/39, l(3)S024639, l(3)S024639b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0050295 Ipk1 Ipk1 http://flybase.org/reports/FBgn0050295 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR009286 inositol pentakisphosphate 2-kinase activity ; GO:0035299 | inferred from mutant phenotype inositol phosphate biosynthetic process ; GO:0032958 | inferred from direct assay - "CG30295, dmIpk1, CG15230, CG15229, CG15228, Ipk1" IPR009286:Inositol-pentakisphosphate 2-kinase CG30295 11-Aug-17 DroID_v2017_08 Drer\ippk - Cele\ippk-1 Xtro\ippk Mmus\Ippk Hsap\IPPK "partially lethal - majority die,some die during pupal stage" FBgn0035511 Cpr64Ab Cuticular protein 64Ab http://flybase.org/reports/FBgn0035511 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr64Ab, CG15007, DmelCpr64Ab" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG15007 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - "partially lethal - majority die,some die during pupal stage" FBgn0035988 CG3982 - http://flybase.org/reports/FBgn0035988 protein_coding_gene - - - "bs12d10.y1, CG3982" IPR015943:WD40/YVTN repeat-like-containing domain CG3982 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0050238 tRNA:Glu-TTC-1-1 transfer RNA:Glutamic acid-TTC 1-1 http://flybase.org/reports/FBgn0050238 tRNA_gene - - - "tRNA:glu4:53A, tRNA:E4:53A, CR30238, tRNA:Glu, chr2R.trna72-GluTTC, tRNA:Glu-TTC-1-1, tRNA:CR30238, tRNA-Glu-TTC-1-1, GAA" - CR30238 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005386 ash1 "absent, small, or homeotic discs 1" http://flybase.org/reports/FBgn0005386 "FBgn0000138, FBgn0004672, FBgn0005228" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR001025 histone methyltransferase activity (H3-K36 specific) ; GO:0046975 | inferred from mutant phenotype histone methyltransferase activity (H3-K36 specific) ; GO:0046975 | inferred from direct assay histone methyltransferase activity (H4-K20 specific) ; GO:0042799 | NOT inferred from direct assay histone acetyltransferase binding ; GO:0035035 | inferred from physical interaction with nej histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | NOT inferred from direct assay histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | inferred from direct assay inferred from mutant phenotype "histone H3-K4 methylation ; GO:0051568 | inferred from direct assay oviposition ; GO:0018991 | inferred from mutant phenotype histone H3-K36 dimethylation ; GO:0097676 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of histone H3-K27 methylation ; GO:0061086 | inferred from mutant phenotype chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype histone H3-K36 methylation ; GO:0010452 | inferred from direct assay" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006560 protein complex ; GO:0043234 | inferred from physical interaction with nej nucleus ; GO:0005634 | inferred by curator from GO:0048096 chromatin ; GO:0000785 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "ASH1, Ash1, CG8887, ash, ash-1, dash, l(3)SG29a, ash1, Ash 1, Ash, l(3)76BDb, ASH-1" "IPR001025:Bromo adjacent homology (BAH) domain, IPR001214:SET domain, IPR001965:Zinc finger, PHD-type, IPR003616:Post-SET domain, IPR006560:AWS domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR001487:Bromodomain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8887 11-Aug-17 DroID_v2017_08 "Drer\setd2, Drer\kmt2e, Drer\setbp1, Drer\setd1ba, Drer\phf3, Drer\phf20b, Drer\whsc1l1, Drer\phf20l1, Drer\ash1l, Drer\kmt2d, Drer\whsc1, Drer\nsd1b" "Scer\SET2, Scer\SET4, Scer\SET3, Scer\RSC2, Scer\CTI6, Scer\BYE1, Scer\SET1" "Cele\C16A11.4, Cele\set-16, Cele\F19B6.3, Cele\set-12, Cele\set-9, Cele\set-20, Cele\mes-4, Cele\set-5, Cele\met-1, Cele\lin-59, Cele\set-19, Cele\set-26" Xtro\setd1b "Mmus\Whsc1, Mmus\Nsd1, Mmus\Kmt2d, Mmus\Setd5, Mmus\Setd1a, Mmus\Phf3, Mmus\Whsc1l1, Mmus\Kmt2e, Mmus\Spocd1, Mmus\Setd1b, Mmus\Phf20l1, Mmus\Setd2, Mmus\Dido1, Mmus\Ash1l, Mmus\Kmt2c, Mmus\Setbp1" "Hsap\SETBP1, Hsap\DIDO1, Hsap\KMT2E, Hsap\SETD1A, Hsap\WHSC1, Hsap\ASH1L, Hsap\SETD5, Hsap\PHF20L1, Hsap\KMT2D, Hsap\NSD1, Hsap\SETD1B, Hsap\SETD2, Hsap\PHF20, Hsap\KMT2C, Hsap\WHSC1L1" " adult stage && oogenesis stage , embryonic stage | early , embryonic stage -- adult stage , larval stage | third instar " " nurse cell

, imaginal disc

" "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage,lethal,short lived,lethal - all die before end of P-stage,some die during pharate adult stage,visible,homeotic,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,non-suppressor of variegation,non-enhancer of variegation,suppressor of variegation,dominant,female limited,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,viable" "abdominal segment 2,abdominal segment 7,male,ovary,heat sensitive,wing,haltere,ectopic,imaginal disc,heart primordium,abdominal segment,metathoracic segment,abdominal segment 6,haltere disc" FBgn0267720 CR46053 - http://flybase.org/reports/FBgn0267720 non_protein_coding_gene - - - CR46053 - CR46053 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040093 lectin-46Ca lectin-46Ca http://flybase.org/reports/FBgn0040093 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 galactose binding ; GO:0005534 | inferred from sequence or structural similarity "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern regulation of female receptivity, post-mating ; GO:0046008 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype sperm competition ; GO:0046692 | inferred from direct assay" extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model cell surface ; GO:0009986 | inferred from direct assay "CG1656, AC007330a, AC 007330A, lectin-46Ca, Lectin-46CA, Lectin-46Ca" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG1656 11-Aug-17 DroID_v2017_08 "Drer\illr1, Drer\si:ch73-343l4.8, Drer\illr4, Drer\si:dkey-187i8.2, Drer\cd209, Drer\LOC101886537, Drer\si:dkey-61f9.1, Drer\si:dkey-61f9.2, Drer\LOC101884526, Drer\illr2, Drer\si:ch211-214k5.3, Drer\LOC101884413, Drer\si:ch211-170d8.5, Drer\si:ch73-361h17.1, Drer\zmp:0000000937, Drer\zgc:174904, Drer\LOC100007376, Drer\si:ch211-133n4.7, Drer\si:ch73-122g19.1, Drer\si:ch73-343l4.2, Drer\illr3, Drer\si:ch73-111e15.1, Drer\zmp:0000000924, Drer\si:ch211-232p21.6, Drer\si:ch211-283g2.3, Drer\LOC100331140, Drer\si:ch73-86n18.1" - "Cele\clec-149, Cele\clec-199, Cele\clec-184, Cele\clec-202, Cele\clec-185, Cele\clec-198, Cele\C25G4.17, Cele\clec-160" - "Mmus\Clec4e, Mmus\Clec4d, Mmus\Cd209e, Mmus\Clec4a2, Mmus\Clec10a, Mmus\Fcer2a, Mmus\Cd209f, Mmus\Clec4b2, Mmus\Cd209c, Mmus\Clec4a1, Mmus\Asgr1, Mmus\Clec4a3, Mmus\Mgl2, Mmus\Clec4n, Mmus\Clec4g, Mmus\Cd207, Mmus\Clec4a4, Mmus\Clec4f, Mmus\Cd209b, Mmus\Cd209a, Mmus\Cd209g, Mmus\Clec4b1, Mmus\Cd209d, Mmus\Asgr2" "Hsap\ASGR1, Hsap\CLEC4F, Hsap\CLEC6A, Hsap\CLEC10A, Hsap\CD209, Hsap\CLEC4D, Hsap\CD207, Hsap\CLEC4C, Hsap\CLEC4A, Hsap\FCER2, Hsap\CLEC17A, Hsap\CLEC4M, Hsap\CLEC4G, Hsap\ASGR2, Hsap\CLEC4E" "mating rhythm defective,viable" FBgn0264546 CG43925 - http://flybase.org/reports/FBgn0264546 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43925 - CG43925 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086404 BG02745 - http://flybase.org/reports/FBgn0086404 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02745 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0003990 vs vesiculated http://flybase.org/reports/FBgn0003990 - gene - - - "bw, vs" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile,partially lethal - majority live,reduced,male,female" wing FBgn0033993 CG8089 - http://flybase.org/reports/FBgn0033993 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003604, InterPro:IPR013087" - - CG8089 "IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG8089 11-Aug-17 DroID_v2017_08 "Drer\LOC101886546, Drer\atmin, Drer\LOC101885450, Drer\LOC101884416, Drer\si:ch73-40a17.4, Drer\LOC100535385, Drer\LOC100332787, Drer\znf1008, Drer\znf1014, Drer\LOC103911751" - "Cele\Y111B2A.10, Cele\C04F5.9, Cele\sdz-12, Cele\Y55F3AM.14, Cele\Y48G8AL.10" "Xtro\zbtb11, Xtro\atmin" "Mmus\Atmin, Mmus\Bnc2" "Hsap\ZFP69, Hsap\BNC2" "viable,fertile" FBgn0011719 Su(top) Suppressor of torpedo http://flybase.org/reports/FBgn0011719 - gene - - - Su(top) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050089 CG30089 - http://flybase.org/reports/FBgn0050089 protein_coding_gene - - - "CG12305, CG12967, CG12966, CG30089" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical" CG30089 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,viable" "ectoderm derivative,neuron,longitudinal connective,ventral nerve cord" DRSC06267 E 0.222556357 0.631911206 7.425979346 0.506528203 0.00366233 -0.69295859 FBgn0012035 Akr Aldo-keto reductase http://flybase.org/reports/FBgn0012035 - gene aldo-keto reductase (NADP) activity ; GO:0004033 | inferred from direct assay - - Akr - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052024 CG32024 - http://flybase.org/reports/FBgn0052024 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG32024 IPR002557:Chitin binding domain CG32024 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022236 l(2)k02520 lethal (2) k02520 http://flybase.net/reports/FBgn0022236.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0037461 CG15177 - http://flybase.org/reports/FBgn0037461 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" - - CG15177 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG15177 11-Aug-17 DroID_v2017_08 "Drer\guca1g, Drer\usp32, Drer\kcnip1a, Drer\si:ch211-103a14.5, Drer\ncalda, Drer\guca1c, Drer\guca1b, Drer\rcvrn2, Drer\si:ch211-245j22.3, Drer\efcab1, Drer\guca1a, Drer\kcnip2, Drer\vsnl1b, Drer\kcnip3b, Drer\hpcal1, Drer\si:ch211-145b13.5, Drer\guca1d, Drer\vsnl1a, Drer\kcnip1b, Drer\kcnip4, Drer\hpca, Drer\rcvrn3, Drer\rcvrna, Drer\guca1e, Drer\ncaldb, Drer\ncs1a, Drer\rcvrnb, Drer\hpcal4, Drer\ncs1b" Scer\FRQ1 - "Xtro\vsnl1, Xtro\guca1a, Xtro\guca1b, Xtro\rcvrn.2, Xtro\hpcal1, Xtro\ncald, Xtro\hpca, Xtro\kcnip3, Xtro\kcnip4, Xtro\kcnip2, Xtro\guca1c, Xtro\ncs1, Xtro\kcnip1, Xtro\efcab1" "Mmus\Rcvrn, Mmus\Guca1b, Mmus\Kcnip1, Mmus\Ncs1, Mmus\Usp32, Mmus\Guca1a, Mmus\Hpcal4, Mmus\1700109H08Rik, Mmus\Hpcal1, Mmus\Kcnip3, Mmus\Ncald, Mmus\Kcnip2, Mmus\Efcab1, Mmus\Vsnl1, Mmus\Kcnip4, Mmus\Hpca" "Hsap\HPCAL4, Hsap\KCNIP3, Hsap\EFCAB1, Hsap\HPCA, Hsap\RCVRN, Hsap\GUCA1A, Hsap\NCS1, Hsap\GUCA1C, Hsap\HPCAL1, Hsap\GUCA1B, Hsap\VSNL1, Hsap\USP32, Hsap\KCNIP4, Hsap\KCNIP2, Hsap\KCNIP1, Hsap\NCALD" "viable,fertile" FBgn0050232 tRNA:Ala-TGC-1-1 transfer RNA:Alanine-TGC 1-1 http://flybase.org/reports/FBgn0050232 tRNA_gene GCA codon-amino acid adaptor activity ; GO:0033455 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033455 cytosol ; GO:0005829 | inferred by curator from GO:0033455 "AE002787.trna12-AlaTGC, tRNA:A:TGC:AE002787-a, CR30232, tRNA[[Ala]], chr2R.trna70-AlaTGC, tRNA-Ala-TGC-1-1, tRNA:Ala-TGC-1-1, tRNA:CR30232, GCA, tRNA[Ala(TGC)]" - CR30232 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010228 HmgZ HMG protein Z http://flybase.org/reports/FBgn0010228 FBgn0063041 protein_coding_gene - - - "HMG-Z, hmg-Z, clone 1.58, dHMG-Z, anon-EST:Liang-1.58, CG17921, BcDNA:RE28596, HmgZ, HMG Z, hmgz, HMG1, HMGZ" IPR009071:High mobility group box domain CG17921 11-Aug-17 DroID_v2017_08 "Drer\tox4b, Drer\tfam, Drer\hmgb3a, Drer\hmg20a, Drer\tox3, Drer\hmgb1a, Drer\ubtf, Drer\ubtfl, Drer\hmgb1b, Drer\hmg20b, Drer\ssrp1a, Drer\hmgb2b, Drer\ssrp1b, Drer\hmgb2a, Drer\tox4a, Drer\hmgb3b, Drer\tox" "Scer\IXR1, Scer\NHP10, Scer\NHP6A, Scer\HMO1, Scer\NHP6B, Scer\POB3, Scer\ABF2" "Cele\hmg-1.1, Cele\hmg-4, Cele\hmg-1.2, Cele\hmg-3" "Xtro\tox, Xtro\hmg20a, Xtro\hmg20b, Xtro\ubtf, Xtro\tfam, Xtro\hmgb1, Xtro\tox3, Xtro\hmgb3, Xtro\tox2, Xtro\hmgb2, Xtro\tox4" "Mmus\Hmgb3, Mmus\Ubtfl1, Mmus\Ssrp1, Mmus\Ubtf, Mmus\Hmg20a, Mmus\Hmg20b, Mmus\Hmgb2, Mmus\Hmgb1, Mmus\Tox2, Mmus\Tox3, Mmus\Tox4, Mmus\Tox, Mmus\Hmgb4, Mmus\Tfam" "Hsap\HMGB4, Hsap\HMG20B, Hsap\UBTF, Hsap\TOX, Hsap\SSRP1, Hsap\TOX3, Hsap\HMGB3, Hsap\HMG20A, Hsap\TOX4, Hsap\HMGB2, Hsap\HMGB1, Hsap\TFAM, Hsap\TOX2" " embryonic stage , larval stage | first instar " viable rhabdomere R7 DRSC03888 E -0.382273936 1.177141099 2.270112586 0.403115766 0.231879163 0.515644364 FBgn0002865 Mst98Ca Male-specific RNA 98Ca http://flybase.org/reports/FBgn0002865 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatid development ; GO:0007286 | inferred from expression pattern sperm flagellum ; GO:0036126 | inferred from direct assay "MST98Ca, Mst, Mst98C, mst336, mst(3)gl-12, Mst98CE, CG11719, Mst98Ca" - CG11719 11-Aug-17 DroID_v2017_08 - - Cele\col-178 - Mmus\Gm7137 - viable DRSC16749 K 0.701349684 -0.173249827 0.24635948 0.425580395 -2.226765935 0.470420068 FBgn0015570 alpha-Est2 alpha-Esterase-2 http://flybase.org/reports/FBgn0015570 - protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay - lipid particle ; GO:0005811 | inferred from direct assay "alphaE2, aE2, B, CG2505, alpha-Est2, DmalphaE2, alpha-EST2, Alpha-Est2" "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG2505 11-Aug-17 DroID_v2017_08 "Drer\nlgn1, Drer\nlgn3a, Drer\ces3, Drer\si:ch211-93f2.1, Drer\nlgn3b, Drer\nlgn2a, Drer\cel.1, Drer\nlgn4b, Drer\cell, Drer\nlgn4a, Drer\nlgn2b, Drer\ces2" - "Cele\F13H6.3, Cele\ace-2, Cele\F15A8.6, Cele\F56C11.6, Cele\T28C12.4, Cele\ace-1, Cele\K11G9.3, Cele\T02B5.3, Cele\R173.3, Cele\B0238.1, Cele\C01B10.10, Cele\K11G9.1, Cele\T28C12.5, Cele\Y71H2AM.13, Cele\K11G9.2, Cele\F07C4.12, Cele\T07H6.1" "Xtro\LOC100494782, Xtro\nlgn4x, Xtro\nlgn2, Xtro\cel, Xtro\nlgn3, Xtro\ces2, Xtro\ces3" "Mmus\Ces1h, Mmus\Ces2e, Mmus\Nlgn2, Mmus\Ces4a, Mmus\Ces5a, Mmus\Ces1d, Mmus\Ces2a, Mmus\Cel, Mmus\Nlgn1, Mmus\Ces2c, Mmus\Ache, Mmus\Ces1c, Mmus\Nlgn3, Mmus\Ces3b, Mmus\Ces1f, Mmus\Ces3a, Mmus\Ces2g, Mmus\Ces1g, Mmus\Ces2b, Mmus\Ces1e, Mmus\Ces1b, Mmus\Ces2f, Mmus\Ces2h" "Hsap\NLGN1, Hsap\CES1, Hsap\ACHE, Hsap\CEL, Hsap\CES4A, Hsap\NLGN2, Hsap\NLGN4X, Hsap\CES2, Hsap\NLGN4Y, Hsap\NLGN3, Hsap\CES3, Hsap\CES5A" viable FBgn0065952 l(2)SH0069 lethal (2) SH0069 http://flybase.org/reports/FBgn0065952 gene - - - "l(2)SH0069, l(2)SH2 0069" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002810 ms(1)516 male sterile (1) 516 http://flybase.org/reports/FBgn0002810 - gene - - - ms(1)516 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,meiotic cell cycle defective,male" "meiosis II & spindle | male,spermatid & nucleus,meiosis II & chromosome, pericentric region,Nebenkern,meiotic cell cycle & centriole | male,meiosis II & aster | male,meiosis II & nuclear chromosome | male,spermatid" FBgn0061044 l(3)S023639 lethal (3) S023639 http://flybase.org/reports/FBgn0061044 gene - - - "0236/39, l(3)S023639" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0052712 CG32712 - http://flybase.org/reports/FBgn0052712 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32712 - CG32712 11-Aug-17 DroID_v2017_08 "Drer\fam73b, Drer\fam73a" - - "Xtro\fam73b, Xtro\fam73a" "Mmus\Miga2, Mmus\Miga1" "Hsap\MIGA1, Hsap\MIGA2" FBgn0266994 CR45445 - http://flybase.org/reports/FBgn0266994 non_protein_coding_gene - - - CR45445 - CR45445 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046697 Ppr-Y Ppr-Y http://flybase.org/reports/FBgn0046697 protein_coding_gene - - - "PPr-Y, CG40440, PprY, Ppr-Y" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR025875:Leucine rich repeat 4" CG40440 11-Aug-17 DroID_v2017_08 "Drer\lrrc23, Drer\si:ch211-103e16.5, Drer\lrriq1, Drer\drc3, Drer\si:dkey-267j14.7, Drer\lrrc61, Drer\lrrc9, Drer\lrguk, Drer\lrrcc1, Drer\ppp1r7, Drer\LOC101885127, Drer\cep97, Drer\lrrc6" "Scer\SDS22, Scer\NUD1" "Cele\dct-3, Cele\K10D2.8" "Xtro\ppp1r7, Xtro\dnal1, Xtro\cep97, Xtro\lrrc23, Xtro\lrrc9, Xtro\lrrc6, Xtro\lrrc56, Xtro\drc3, Xtro\lrrc49, Xtro\lrrcc1" "Mmus\Lrguk, Mmus\Lrriq3, Mmus\Lrrc61, Mmus\Dnal1, Mmus\Lrrc9, Mmus\Lrriq1, Mmus\Lrrc48, Mmus\Lrrcc1, Mmus\Lrrc49, Mmus\Cep97, Mmus\Lrrc56, Mmus\Lrrc43, Mmus\Ppp1r7, Mmus\Lrrc6, Mmus\Lrrc46, Mmus\Cntrl, Mmus\Lrrc23" "Hsap\LRRC46, Hsap\LRRC49, Hsap\LRRIQ1, Hsap\DRC3, Hsap\CNTRL, Hsap\LRRC23, Hsap\LRRC61, Hsap\PPP1R7, Hsap\LRRCC1, Hsap\DNAL1, Hsap\LRRC56, Hsap\LRGUK, Hsap\LRRIQ3, Hsap\LRRC43, Hsap\CEP97, Hsap\LRRC6" FBgn0039928 Cals Calsyntenin-1 http://flybase.org/reports/FBgn0039928 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919, InterPro:IPR026914 calcium ion binding ; GO:0005509 | inferred from sequence model" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model postsynaptic membrane ; GO:0045211 | inferred from sequence or structural similarity with UniProtKB:Q9EPL2 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:Q9EPL2 "CALS, DCad102F, Cad102F, CG11059, CT30877, Cals, cals" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR026914:Calsyntenin, IPR013320:Concanavalin A-like lectin/glucanase domain" CG11059 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-276c2.2, Drer\clstn3, Drer\clstn2, Drer\clstn1" - Cele\casy-1 "Xtro\clstn2, Xtro\clstn3, Xtro\LOC100216037, Xtro\clstn3" "Mmus\Clstn1, Mmus\Clstn3, Mmus\Clstn2" "Hsap\CLSTN1, Hsap\CLSTN2, Hsap\CLSTN3" "viable,fertile" FBgn0067403 Rst(2)DDT-EMS1 Resistant to DDT on II EMS1 http://flybase.org/reports/FBgn0067403 gene - - - "Rst(2)DDT, Rst(2)DDT-EMS1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0265984 CR44763 - http://flybase.org/reports/FBgn0265984 non_protein_coding_gene - - - "lincRNA.377, CR44763" - CR44763 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030341 p24-1 p24-related-1 http://flybase.org/reports/FBgn0030341 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence or structural similarity transporter activity ; GO:0005215 | inferred from sequence model reproduction ; GO:0000003 | inferred from mutant phenotype regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred from sequence model positive regulation of Wnt protein secretion ; GO:0061357 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 transport vesicle ; GO:0030133 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG1967, clone 1.45, anon-EST:Liang-1.45, p24-1, p24.1, p24, p26/p24gamma4" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG1967 11-Aug-17 DroID_v2017_08 "Drer\tmed5, Drer\tmed3, Drer\tmed1b, Drer\tmed7" "Scer\EMP24, Scer\ERP2, Scer\ERP3, Scer\ERP4" "Cele\F57B10.5, Cele\K08E4.6" "Xtro\tmed1, Xtro\tmed7" "Mmus\Tmed7, Mmus\Tmed5, Mmus\Ticam2, Mmus\Tmed3, Mmus\Tmed1" "Hsap\TMED5, Hsap\TMED7-TICAM2, Hsap\TMED3, Hsap\TMED7, Hsap\TICAM2, Hsap\TMED1" "viable,fertile,lethal,neuroanatomy defective,female semi-sterile,male sterile,male semi-sterile" "embryonic/larval neuroblast,ganglion mother cell,wing margin" FBgn0267090 CR45534 - http://flybase.org/reports/FBgn0267090 non_protein_coding_gene - - - CR45534 - CR45534 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085562 CG41232 - http://flybase.org/reports/FBgn0085562 protein_coding_gene - - - CG41232 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005090 fs(2)OWc2 female sterile (2) OWc2 http://flybase.org/reports/FBgn0005090 - gene - - - fs(2)OWc2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266594 CR45119 - http://flybase.org/reports/FBgn0266594 non_protein_coding_gene - - - CR45119 - CR45119 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051860 ZnT33D Zinc transporter 33D http://flybase.org/reports/FBgn0051860 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016323 zinc ion transmembrane transporter activity ; GO:0005385 | inferred from sequence or structural similarity with UniProtKB:Q62941 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002524 detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype response to zinc ion ; GO:0010043 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 cellular zinc ion homeostasis ; GO:0006882 | inferred from mutant phenotype regulation of sequestering of zinc ion ; GO:0061088 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 zinc II ion transport ; GO:0006829 | inferred from sequence or structural similarity with UniProtKB:Q62941 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002524 basolateral plasma membrane ; GO:0016323 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from biological aspect of ancestor with PANTHER:PTN000169638 "CG17215, dZnT33D, CG31860, ZnT33D, cg31860" "IPR002524:Cation efflux protein, IPR027470:Cation efflux protein, cytoplasmic domain" CG31860 11-Aug-17 DroID_v2017_08 "Drer\slc30a4, Drer\slc30a8, Drer\slc30a2" "Scer\ZRC1, Scer\COT1" Cele\cdf-2 "Xtro\slc30a3, Xtro\slc30a4, Xtro\slc30a8, Xtro\slc30a2" "Mmus\Slc30a2, Mmus\Slc30a8, Mmus\Slc30a3, Mmus\Slc30a4" "Hsap\SLC30A3, Hsap\SLC30A2, Hsap\SLC30A4, Hsap\SLC30A8" "lethal,visible,some die during pupal stage,body color defective,lethal - all die during larval stage" "eye,adult thorax,humeral bristle" FBgn0065704 l(2)SH0618 lethal (2) SH0618 http://flybase.org/reports/FBgn0065704 gene - - - "l(2)SH0618, l(2)SH2 0618" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041771 anon-d29 anon-d29 http://flybase.org/reports/FBgn0041771 gene - - - "d29, anon-d29" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032638 SPH93 Serine protease homolog 93 http://flybase.org/reports/FBgn0032638 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues molecular_function ; GO:0003674 | no biological data available "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern" cellular_component ; GO:0005575 | no biological data available "SPH93, c-SPH93, CG6639" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG6639 11-Aug-17 DroID_v2017_08 Drer\masp2 - Cele\try-1 - "Mmus\Prss51, Mmus\Prss46, Mmus\Klk1b8, Mmus\Klk1, Mmus\Klkb1, Mmus\Klk1b24, Mmus\Klk1b26, Mmus\Klk1b11, Mmus\Klk1b9, Mmus\Klk1b16, Mmus\Klk11, Mmus\Klk1b21, Mmus\Klk1b22, Mmus\F11, Mmus\Klk1b3, Mmus\Klk1b27, Mmus\Egfbp2, Mmus\Klk1b4, Mmus\Klk1b1, Mmus\Klk1b5" "Hsap\KLK2, Hsap\KLK11, Hsap\F11, Hsap\PRSS21, Hsap\KLK3, Hsap\KLKB1, Hsap\KLK1" "lethal,viable" FBgn0023080 h::Kr h::Kr http://flybase.org/reports/FBgn0023080 - engineered_fusion_gene - - - h::Kr - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially" "abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8" FBgn0024263 acd(2)5M38 auditory courtship defective 5M38 http://flybase.org/reports/FBgn0024263 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5M38 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,auditory perception defective" FBgn0005354 su(fa[swb]) suppressor of facet-strawberry http://flybase.org/reports/FBgn0005354 - gene - - - su(fa[swb]) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029693 CG6379 - http://flybase.org/reports/FBgn0029693 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467 mRNA (nucleoside-2'-O-)-methyltransferase activity ; GO:0004483 | inferred from sequence or structural similarity with UniProtKB:Q8N1G2 7-methylguanosine mRNA capping ; GO:0006370 | inferred from sequence or structural similarity with UniProtKB:Q8N1G2 mRNA methylation ; GO:0080009 | inferred from sequence or structural similarity with UniProtKB:Q8N1G2 cap1 mRNA methylation ; GO:0097309 | inferred from sequence or structural similarity with UniProtKB:Q8N1G2 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q8N1G2 CG6379 "IPR025816:RrmJ-type ribose 2-O-methyltransferase domain, IPR000467:G-patch domain, IPR002877:Ribosomal RNA methyltransferase FtsJ domain, IPR030376:Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG6379 11-Aug-17 DroID_v2017_08 Drer\cmtr1 - Cele\Y53F4B.13 Xtro\cmtr1 "Mmus\Rnf8, Mmus\Cmtr1" Hsap\CMTR1 "viable,fertile" FBgn0265169 CR44238 - http://flybase.org/reports/FBgn0265169 non_protein_coding_gene - - - CR44238 - CR44238 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069179 mcl(2)Z2641 mcl(2)Z2641 http://flybase.org/reports/FBgn0069179 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z2641 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0250834 CG33308 - http://flybase.org/reports/FBgn0250834 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG33308, HDC02577, BP1076, anon-SAGE:Wang-042" - CG33308 11-Aug-17 DroID_v2017_08 - - - - - - DRSC01419 IE 0.165505781 -1.779915254 -1.763961375 -1.239442783 0.615520235 -0.825164962 FBgn0259224 CG42324 - http://flybase.org/reports/FBgn0259224 protein_coding_gene - - - "CG42324, CG14972, CG14973" - CG42324 11-Aug-17 DroID_v2017_08 "Drer\tjap1, Drer\si:dkey-174m14.3" - - - "Mmus\Tjap1, Mmus\Begain" "Hsap\TJAP1, Hsap\BEGAIN" FBgn0011066 l(1)Q19 lethal (1) Q19 http://flybase.org/reports/FBgn0011066 FBgn0010210 gene - - - l(1)Q19 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014224 l(2)31Ec lethal (2) 31Ec http://flybase.org/reports/FBgn0014224 - gene - - - l(2)31Ec - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085817 CR41607 - http://flybase.org/reports/FBgn0085817 rRNA_gene - - - CR41607 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011449 l(3)neo5 lethal (3) neo5 http://flybase.org/reports/FBgn0011449 - gene - - - l(3)neo5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035817 CG7409 - http://flybase.org/reports/FBgn0035817 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model protein refolding ; GO:0042026 | inferred from direct assay response to heat ; GO:0009408 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "Dmel46.9, CT16169, CG7409" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG7409 11-Aug-17 DroID_v2017_08 "Drer\hspb7, Drer\hspb9, Drer\cryaa, Drer\hspb3, Drer\hspb11, Drer\cryaba, Drer\hspb6, Drer\hspb15, Drer\si:dkey-1k23.3, Drer\hspb1, Drer\hspb8, Drer\hspb12, Drer\hspb2" - "Cele\ZK1128.7, Cele\sip-1, Cele\F08H9.4, Cele\hsp-12.1, Cele\hsp-43, Cele\hsp-12.6, Cele\hsp-16.11, Cele\Y55F3BR.6, Cele\hsp-17, Cele\hsp-16.2, Cele\hsp-16.48, Cele\hsp-16.49, Cele\hsp-16.41, Cele\hsp-12.2, Cele\hsp-16.1, Cele\hsp-12.3, Cele\F08H9.3" "Xtro\cryaa, Xtro\hspb6, Xtro\hspb8, Xtro\hsp30e, Xtro\cryab, Xtro\hspb3, Xtro\hsp30d, Xtro\hspb2, Xtro\hspb1, Xtro\uqcrh" "Mmus\Hspb8, Mmus\Hspb6, Mmus\Cryab, Mmus\Hspb1, Mmus\Cryaa, Mmus\Hspb7, Mmus\Hspb2, Mmus\Hspb3, Mmus\Hspb9" "Hsap\CRYAA, Hsap\HSPB6, Hsap\HSPB8, Hsap\HSPB9, Hsap\CRYAB, Hsap\HSPB3, Hsap\HSPB2, Hsap\LOC102724652, Hsap\HSPB1, Hsap\HSPB7" viable DRSC10842 K 0.697776589 0.820126421 -0.181723297 0.842768195 0.565623854 1.514161403 FBgn0033108 CG15236 - http://flybase.org/reports/FBgn0033108 protein_coding_gene - - - CG15236 "IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain" CG15236 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0034403 CG18190 - http://flybase.org/reports/FBgn0034403 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR004953, InterPro:IPR027328" - microtubule associated complex ; GO:0005875 | inferred from direct assay CG18190 "IPR001715:Calponin homology domain, IPR004953:EB1, C-terminal, IPR027328:Microtubule-associated protein RP/EB" CG18190 11-Aug-17 DroID_v2017_08 "Drer\mapre3a, Drer\mapre1b, Drer\mapre2, Drer\mapre1a, Drer\mapre3b" Scer\BIM1 "Cele\ebp-1, Cele\ebp-3, Cele\ebp-2" Xtro\mapre1 "Mmus\Mapre1, Mmus\Mapre2, Mmus\Mapre3" "Hsap\MAPRE2, Hsap\MAPRE1, Hsap\MAPRE3" FBgn0039911 CG1909 - http://flybase.org/reports/FBgn0039911 protein_coding_gene protein anchor ; GO:0043495 | inferred from electronic annotation with InterPro:IPR019568 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 acetylcholine receptor binding ; GO:0033130 | inferred from sequence or structural similarity with HGNC:9863 zinc ion binding ; GO:0008270 | inferred from sequence model "regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype synaptic transmission, cholinergic ; GO:0007271 | inferred from sequence or structural similarity with HGNC:9863" - CG1909 "IPR001841:Zinc finger, RING-type, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019568:Rapsyn, myristoylation/linker region, N-terminal, IPR024812:Tetratricopeptide repeat protein 24, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1909 11-Aug-17 DroID_v2017_08 Drer\rapsn - Cele\rpy-1 Xtro\rapsn "Mmus\Ttc24, Mmus\Rapsn" "Hsap\RAPSN, Hsap\TTC24" viable FBgn0030628 CG9114 - http://flybase.org/reports/FBgn0030628 protein_coding_gene - - - CG9114 - CG9114 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC20155 K 0.027022366 1.355397897 -0.251801936 -0.017977546 -1.70615625 -0.539850059 FBgn0265598 Bx Beadex http://flybase.org/reports/FBgn0265598 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 protein binding ; GO:0005515 | inferred from physical interaction with pnr inferred from physical interaction with chianti "leg disc development ; GO:0035218 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inferred from genetic interaction with ap regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype reproductive process ; GO:0022414 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype response to cocaine ; GO:0042220 | inferred from mutant phenotype gastric emptying ; GO:0035483 | inferred from mutant phenotype imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype" nucleus ; GO:0005634 | non-traceable author statement "CG44425, dLMO, Bx, LMO, dlmo, Lmo, hdp, DLMO, CG6500, Bd, beadex/dLMO, dttg, Dlmo, hld, fliH, dLmo, hdp-a, Ptd, Rho, CG10548, CG15048, bx" "IPR001781:Zinc finger, LIM-type" CG44425 11-Aug-17 DroID_v2017_08 "Drer\lmo3, Drer\si:dkey-90l8.3, Drer\lmo1, Drer\lmo4a, Drer\lmo2, Drer\zgc:56628" Scer\RGA2 Cele\lin-11 "Xtro\lmo2, Xtro\lmo4.1" "Mmus\Lmo4, Mmus\Lmo1, Mmus\Lmo3, Mmus\Lmo2" "Hsap\LMO3, Hsap\LMO2, Hsap\LMO1, Hsap\LMO4" FBgn0085738 CR40503 - http://flybase.org/reports/FBgn0085738 rRNA_gene - - - CR40503 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038213 CG9624 - http://flybase.org/reports/FBgn0038213 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9624 "IPR015795:Pyruvate kinase, C-terminal" CG9624 11-Aug-17 DroID_v2017_08 - - "Cele\F46F5.14, Cele\F41D3.11, Cele\F31F4.1" - - - viable FBgn0024711 anon-63Ea anon-63Ea http://flybase.org/reports/FBgn0024711 - gene - - - anon-63Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038719 CG16727 - http://flybase.org/reports/FBgn0038719 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG16727 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG16727 11-Aug-17 DroID_v2017_08 "Drer\slc22a7b.3, Drer\zgc:175176, Drer\LOC100334012, Drer\sv2, Drer\slc22a7b.2, Drer\zmp:0000001102, Drer\slc22a21, Drer\slc22a6l, Drer\LOC101884074, Drer\slc22a5, Drer\oatx, Drer\slc22a13, Drer\slc22a7b.1" "Scer\YHK8, Scer\TPO2, Scer\HXT9, Scer\TPO1, Scer\PHO84, Scer\QDR3, Scer\AQR1, Scer\HXT5, Scer\DTR1, Scer\QDR2, Scer\HXT2, Scer\TPO3, Scer\GIT1, Scer\QDR1, Scer\FLR1" "Cele\C46C2.2, Cele\Y66D12A.13, Cele\Y57G11C.23, Cele\ZK892.3, Cele\C06H5.6, Cele\C53B4.1, Cele\oct-1, Cele\B0361.11, Cele\B0252.3, Cele\T22F7.1, Cele\Y51A2D.18" Xtro\slc22a6 "Mmus\Slc22a26, Mmus\Slc22a8, Mmus\Slc22a14, Mmus\Slc22a29, Mmus\Slc22a5, Mmus\Slc22a19, Mmus\Slc22a22, Mmus\Sv2c, Mmus\Slc22a16, Mmus\Slc22a20, Mmus\Svop, Mmus\Slc22a27, Mmus\Slc22a23, Mmus\Slc22a21, Mmus\Slc22a7, Mmus\Slc22a2, Mmus\Slc22a4, Mmus\Slc22a28, Mmus\Slc22a30, Mmus\Slc22a6" "Hsap\SLC22A8, Hsap\SLC22A25, Hsap\SLC22A10, Hsap\SLC22A1, Hsap\SLC22A4, Hsap\SVOP, Hsap\SV2C, Hsap\SLC22A9, Hsap\SLC22A6, Hsap\SLC22A5, Hsap\SV2B, Hsap\SLC22A7, Hsap\SLC22A23, Hsap\SLC22A11, Hsap\SLC22A2, Hsap\SLC22A12, Hsap\SLC22A24" viable FBgn0039787 CG9702 - http://flybase.org/reports/FBgn0039787 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 CG9702 "IPR002645:STAS domain, IPR011547:SLC26A/SulP transporter domain, IPR001902:SLC26A/SulP transporter" CG9702 11-Aug-17 DroID_v2017_08 "Drer\slc26a6, Drer\si:ch211-117c9.2, Drer\slc26a1, Drer\slc26a4, Drer\slc26a2, Drer\slc26a10, Drer\slc26a5, Drer\slc26a3.1, Drer\slc26a3.2, Drer\slc26a11, Drer\slc26a6l" "Scer\SUL2, Scer\YPR003C, Scer\YGR125W, Scer\SUL1" "Cele\sulp-4, Cele\sulp-2, Cele\sulp-6, Cele\sulp-1, Cele\sulp-3, Cele\sulp-5, Cele\sulp-7, Cele\sulp-8" "Xtro\slc26a9, Xtro\slc26a1, Xtro\slc26a6, Xtro\slc26a10, Xtro\slc26a5, Xtro\slc26a11, Xtro\slc26a2, Xtro\slc26a4, Xtro\slc26a7" "Mmus\Slc26a5, Mmus\Slc26a10, Mmus\Slc26a2, Mmus\Slc26a4, Mmus\Slc26a9, Mmus\Slc26a8, Mmus\Slc26a7, Mmus\Slc26a1, Mmus\Slc26a3, Mmus\Slc26a6, Mmus\Slc26a11" "Hsap\SLC26A7, Hsap\SLC26A4, Hsap\SLC26A6, Hsap\SLC26A2, Hsap\SLC26A11, Hsap\SLC26A10, Hsap\SLC26A9, Hsap\SLC26A5, Hsap\SLC26A3, Hsap\SLC26A1, Hsap\SLC26A8" "partially lethal - majority die,some die during pupal stage" FBgn0001637 l(1)dn17 lethal (1) discs normal 17 http://flybase.org/reports/FBgn0001637 - gene - - - "l(1)d.norm.-17, l(1)dn17" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0016731 SR3-10 Suppressor of Ras85D 3-10 http://flybase.org/reports/FBgn0016731 - gene - - - SR3-10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052274 Drsl1 Drosomycin-like 1 http://flybase.org/reports/FBgn0052274 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs defense response to fungus ; GO:0050832 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro1, CG11520, Dro-1, Dro-H, dro1b, CG32274, Drs-lC, Drs-I, Drs-l, Drsl1" "IPR003614:Knottin, scorpion toxin-like" CG32274 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263488 CR43603 - http://flybase.org/reports/FBgn0263488 non_protein_coding_gene - - - "unsRNA:CG10576-a, CR43603" - CR43603 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038280 CG14861 - http://flybase.org/reports/FBgn0038280 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - CG14861 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG14861 11-Aug-17 DroID_v2017_08 "Drer\efhd1, Drer\efhd2" - "Cele\efhd-1, Cele\C50C3.5" "Xtro\efhd2, Xtro\efhd1" "Mmus\Efhd2, Mmus\Efhd1" "Hsap\EFHD2, Hsap\EFHD1" viable FBgn0263474 scaRNA:PsiU2-38.40.42 small Cajal body-specific RNA : PsiU2-38.40.42 http://flybase.org/reports/FBgn0263474 snoRNA_gene snRNA pseudouridylation guide activity ; GO:0030565 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "scaRNA:PsiU2-38.40.42, pugU2-38/40/42, snoRNA:bur-a" - CR43589 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033829 CG17062 - http://flybase.org/reports/FBgn0033829 protein_coding_gene - - - CG17062 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034072 Dg Dystroglycan http://flybase.org/reports/FBgn0034072 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR015919 structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC:2666 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q0KI50 inferred from physical interaction with UniProtKB:Q7YU29 inferred from physical interaction with UniProtKB:Q9VDW3 inferred from physical interaction with UniProtKB:Q9VDW6 protein binding ; GO:0005515 | inferred from physical interaction with Dys cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from electronic annotation with InterPro:IPR008465 cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype regulation of glycolytic process ; GO:0006110 | inferred from genetic interaction with Pgk establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype establishment or maintenance of apical/basal cell polarity ; GO:0035088 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype regulation of production of miRNAs involved in gene silencing by miRNA ; GO:1903798 | inferred from direct assay axon guidance ; GO:0007411 | inferred from genetic interaction with dock actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype oocyte axis specification ; GO:0007309 | inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype establishment or maintenance of polarity of follicular epithelium ; GO:0016334 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype dystroglycan complex ; GO:0016011 | inferred from sequence or structural similarity with HGNC:2666 dystroglycan complex ; GO:0016011 | inferred from direct assay dystroglycan complex ; GO:0016011 | inferred from sequence or structural similarity neuromuscular junction ; GO:0031594 | inferred from direct assay dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from physical interaction with Dys plasma membrane ; GO:0005886 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay basal plasma membrane ; GO:0009925 | inferred from direct assay sarcolemma ; GO:0042383 | inferred from direct assay T-tubule ; GO:0030315 | inferred from direct assay "Dg, dg, DG, CG18250, dys, dgn, CT41273, DmDG, atu" "IPR006644:Dystroglycan-type cadherin-like, IPR008465:Dystroglycan, IPR030398:DG-type SEA domain, IPR015919:Cadherin-like, IPR027468:Alpha-dystroglycan domain 2, IPR013783:Immunoglobulin-like fold" CG18250 11-Aug-17 DroID_v2017_08 Drer\dag1 - "Cele\dgn-2, Cele\R09F10.3, Cele\dgn-3, Cele\dgn-1" Xtro\dag1 Mmus\Dag1 Hsap\DAG1 "behavior defective,thermotaxis behavior defective,cell polarity defective,neurophysiology defective,visible,partially lethal - majority live,viable,lethal - all die before end of larval stage,some die during third instar larval stage,germline clone,neuroanatomy defective,somatic clone,cell autonomous,cell non-autonomous,locomotor behavior defective,conditional,partially lethal - majority die,some die during larval stage" "oocyte,embryonic/larval neuromuscular junction,crossvein,stress fiber,follicle cell,egg,maternal effect,stress fiber | cell autonomous | somatic clone,cell autonomous,somatic clone,hemocyte,leg,wing,eye,stage S6 oocyte,germline clone,embryonic/larval muscle system,muscle attachment site,sarcomere | second instar larval stage,posterior crossvein,ring canal,eye photoreceptor cell,lamina plexus,eye disc,cell non-autonomous,glial cell,oocyte associated follicle cell,embryonic/larval muscle system | third instar larval stage,sarcomere | third instar larval stagetub.PU,indirect flight muscle,conditional,lamina plexus | third instar larval stage,eye disc | third instar larval stage,eye photoreceptor cell | third instar larval stage,sarcomere | third instar larval stagehow-24B" FBgn0041752 hexe hexe http://flybase.org/reports/FBgn0041752 gene - - - hexe - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,recessive,lethal,hyperplasia,chemical resistant,dominant" "polytene chromosome,melanotic mass,embryonic/larval brain,salivary gland" FBgn0002649 Margin Margin http://flybase.org/reports/FBgn0002649 - gene - - - "Margin, Mar" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" wing FBgn0001387 l(1)2Bs lethal (1) 2Bs http://flybase.org/reports/FBgn0001387 - gene - - - l(1)2Bs - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0021934 l(2)k11009 lethal (2) k11009 http://flybase.org/reports/FBgn0021934 - gene - - - l(2)k11009 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040752 Prosap Prosap http://flybase.org/reports/FBgn0040752 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with homer GKAP/Homer scaffold activity ; GO:0030160 | inferred from sequence or structural similarity with RGD:69264 synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype postsynaptic density assembly ; GO:0097107 | inferred from sequence or structural similarity with MGI:MGI:1930016 regulation of non-canonical Wnt signaling pathway ; GO:2000050 | inferred from mutant phenotype subsynaptic reticulum organization ; GO:1990255 | inferred from mutant phenotype neuromuscular junction ; GO:0031594 | inferred from direct assay postsynaptic density ; GO:0014069 | inferred from direct assay postsynaptic density ; GO:0014069 | inferred from sequence or structural similarity with RGD:69264 "D-ProSAP, Shank, CG8122, CG13354, CG30483, BcDNA:GH23107, anon-WO0118547.149, Prosap, ProSAP, prosap" "IPR001452:SH3 domain, IPR001478:PDZ domain, IPR002110:Ankyrin repeat, IPR011511:Variant SH3 domain, IPR020683:Ankyrin repeat-containing domain, IPR032425:Talin, N-terminal F0 domain" CG30483 11-Aug-17 DroID_v2017_08 "Drer\il16, Drer\grip2b, Drer\si:dkey-92i15.4, Drer\shank2, Drer\pdzd7b, Drer\shank3a, Drer\slc9a3r1, Drer\shank1, Drer\pard3bb, Drer\inadl, Drer\shank3b, Drer\grip1, Drer\grid2ipa, Drer\lnx1, Drer\dlg5a" - Cele\shn-1 "Xtro\grip2, Xtro\dlg5, Xtro\shank3, Xtro\grip1, Xtro\shank1, Xtro\shank2, Xtro\grid2ip, Xtro\lnx1" "Mmus\Shank3, Mmus\Pdzd11, Mmus\Grip1, Mmus\Grid2ip, Mmus\Lnx1, Mmus\Il16, Mmus\Shank1, Mmus\Dlg5, Mmus\Grasp, Mmus\Ush1c, Mmus\Mpdz, Mmus\Grip2, Mmus\Patj, Mmus\Pdzd2, Mmus\Shank2, Mmus\Pdzph1" "Hsap\IL16, Hsap\CASKIN1, Hsap\FRMPD2, Hsap\USH1C, Hsap\GRIP1, Hsap\GRID2IP, Hsap\GRASP, Hsap\SHANK2, Hsap\MPDZ, Hsap\SHANK3, Hsap\PDZD2, Hsap\DLG5, Hsap\PATJ, Hsap\SHANK1, Hsap\LNX1, Hsap\PARD3B" "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0032640 Sgt small glutamine-rich tetratricopeptide containing protein http://flybase.org/reports/FBgn0032640 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of chaperone-mediated protein folding ; GO:1903646 | inferred from direct assay negative regulation of protein oligomerization ; GO:0032460 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "dsgt, CG5094, Sgt" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1, IPR032374:SGTA, homodimerisation domain" CG5094 11-Aug-17 DroID_v2017_08 "Drer\ttc4, Drer\sgtb, Drer\tomm34, Drer\dyx1c1, Drer\zgc:123010, Drer\ttc12, Drer\si:dkey-33c12.4, Drer\spag1a, Drer\tex11, Drer\spag1b, Drer\sgta" "Scer\SGT2, Scer\CNS1, Scer\TOM71, Scer\TOM70" "Cele\sgt-1, Cele\C33H5.8" "Xtro\sgtb, Xtro\sgta" "Mmus\Dyx1c1, Mmus\Ttc4, Mmus\Sgta, Mmus\Tex11, Mmus\Spag1, Mmus\Sgtb, Mmus\Tomm34" "Hsap\TOMM34, Hsap\SPAG1, Hsap\TEX11, Hsap\TTC31, Hsap\SGTA, Hsap\SGTB, Hsap\TTC4, Hsap\DYX1C1" viable DRSC02812 I -0.062351427 -2.370778344 -0.873431057 1.249921019 0.3761155 -0.086711019 FBgn0051703 CG31703 - http://flybase.org/reports/FBgn0051703 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004343 RNA polymerase II C-terminal domain phosphoserine binding ; GO:1990269 | inferred from biological aspect of ancestor with PANTHER:PTN000319032 transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from biological aspect of ancestor with PANTHER:PTN000319032" histone modification ; GO:0016570 | inferred from electronic annotation with InterPro:IPR031102 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from electronic annotation with InterPro:IPR031102 Cdc73/Paf1 complex ; GO:0016593 | inferred from biological aspect of ancestor with PANTHER:PTN000319032 CG31703 "IPR004343:Plus-3 domain, IPR031102:RNA polymerase-associated protein Rtf1" CG31703 11-Aug-17 DroID_v2017_08 Drer\rtf1 Scer\RTF1 Cele\rtfo-1 Xtro\rtf1 Mmus\Rtf1 Hsap\RTF1 FBgn0283435 CR46279 - http://flybase.org/reports/FBgn0283435 pseudogene_attribute - - - "CR46279, CG12717-related" - CR46279 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264525 ff12 - http://flybase.org/reports/FBgn0264525 gene - - - ff12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" FBgn0262484 CG43074 - http://flybase.org/reports/FBgn0262484 protein_coding_gene - - - CG43074 - CG43074 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020804 ms(3)A81 ms(3)A81 http://flybase.org/reports/FBgn0020804 - gene - - - "3-A81, ms(3)A81" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile,partially,chemical sensitive" FBgn0015827 T-D14.1 T-D14.1 http://flybase.org/reports/FBgn0015827 - gene - - - T-D14.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263077 CG43340 - http://flybase.org/reports/FBgn0263077 protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG30492, BcDNA:HL07907, CG17984, CG17983, CG43340, CG30494, CT6764, CG2088, BcDNA:GH02712, CG2080" "IPR011011:Zinc finger, FYVE/PHD-type" CG43340 11-Aug-17 DroID_v2017_08 "Drer\leo1, Drer\rp1, Drer\akap12a" Scer\YFR016C - Xtro\leo1 "Mmus\Dmp1, Mmus\Ibsp, Mmus\Asxl3, Mmus\BC051142, Mmus\Rp1, Mmus\Leo1" "Hsap\IBSP, Hsap\LEO1, Hsap\RP1, Hsap\DMP1" FBgn0033130 Tsp42Ei Tetraspanin 42Ei http://flybase.org/reports/FBgn0033130 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "CG12843, Tsp42EI, Dm.Tsp42Ei, Tsp42Ei" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12843 11-Aug-17 DroID_v2017_08 "Drer\cd63, Drer\prph2a, Drer\prph2b, Drer\rom1b, Drer\tspan3b, Drer\tspan3a, Drer\tspan36, Drer\zmp:0000000545, Drer\rom1a, Drer\prph2l" - "Cele\tsp-7, Cele\tsp-5, Cele\tsp-21, Cele\tsp-18" - "Mmus\Prph2, Mmus\Cd63, Mmus\Tspan3" "Hsap\TSPAN3, Hsap\PRPH2" "viable,fertile" FBgn0266429 AstA-R1 Allatostatin A receptor 1 http://flybase.org/reports/FBgn0266429 protein_coding_gene allatostatin receptor activity ; GO:0008261 | inferred from sequence or structural similarity allatostatin receptor activity ; GO:0008261 | inferred from physical interaction with AstA neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "DAR1, AlstR, AstA-R1, CG2872, D.AlstR1, DAR-1, EG:121E7.2, DGR, GR, AST-R, ASR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000405:Galanin receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG2872 11-Aug-17 DroID_v2017_08 "Drer\cntn2, Drer\cxcr4a, Drer\LOC797181, Drer\LOC101884253, Drer\si:ch73-160i9.1, Drer\ccr7, Drer\cmklr1, Drer\ackr4b, Drer\si:ch211-171h4.6, Drer\xcr1b.2, Drer\gpr19, Drer\igsf9ba, Drer\LOC100151078, Drer\kiss1rb, Drer\LOC793148, Drer\LOC100005512, Drer\cxcr4b, Drer\ackr4a, Drer\ccr12b.2, Drer\LOC100006764, Drer\gpr183a, Drer\ccr9b, Drer\LOC103908669, Drer\oxtrl, Drer\xcr1a.1, Drer\LOC101885604, Drer\hcrtr2, Drer\nmur1a, Drer\ccr8.1, Drer\si:dkey-202l22.3, Drer\nmur3, Drer\galr1b, Drer\cxcr3.2, Drer\ackr3b, Drer\si:dkey-42l23.5, Drer\cxcr2, Drer\ccr12b.1, Drer\fpr1, Drer\ccr6a, Drer\ackr3a, Drer\LOC793479, Drer\p2ry1, Drer\cntn1b, Drer\cysltr1, Drer\sc:d217, Drer\neo1a, Drer\p2ry6, Drer\prlh2r, Drer\gpr17, Drer\zgc:194312, Drer\kiss1ra, Drer\gpr4, Drer\nmur1b, Drer\si:ch211-207g17.3, Drer\taar14f, Drer\galr2b, Drer\ccdc141, Drer\si:ch73-160i9.3, Drer\si:dkey-211g8.1, Drer\cntn1a, Drer\galr1a, Drer\si:dkey-117a8.1, Drer\si:dkey-42l23.7, Drer\LOC101882856, Drer\xcr1b.1, Drer\LOC101884647, Drer\cabz01093075.1, Drer\igsf9bb, Drer\ccr12a, Drer\zgc:194202, Drer\si:ch211-240b21.5, Drer\npy7r, Drer\ccr9a, Drer\zmp:0000001069" - "Cele\srx-41, Cele\srx-34, Cele\srx-48, Cele\srx-80, Cele\srx-35, Cele\srx-59, Cele\srx-53, Cele\srx-82, Cele\srx-93, Cele\srx-74, Cele\srx-56, Cele\srx-55, Cele\srx-64, Cele\srx-63, Cele\srx-24, Cele\srx-31, Cele\srx-85, Cele\srx-36, Cele\srx-66, Cele\srx-54, Cele\srx-29, Cele\srx-22, Cele\srx-23, Cele\srx-86, Cele\srx-62, Cele\srx-21, Cele\srx-51, Cele\srx-19, Cele\srx-90, Cele\fbxa-199, Cele\srx-46, Cele\srx-45, Cele\srx-60, Cele\npr-34, Cele\srx-33, Cele\npr-24, Cele\srx-68, Cele\srx-12, Cele\srx-50, Cele\tkr-3, Cele\srx-98, Cele\srx-84, Cele\srx-58, Cele\srx-67, Cele\srx-28, Cele\srx-16, Cele\srx-13, Cele\srx-20, Cele\srx-32, Cele\srx-39, Cele\srx-87, Cele\srx-43, Cele\srx-65, Cele\npr-9, Cele\srx-47, Cele\srx-77, Cele\srx-92, Cele\srx-38, Cele\srx-116, Cele\srx-18, Cele\srx-104, Cele\srx-125, Cele\srx-26, Cele\srx-134" "Xtro\cxcr3, Xtro\kiss1r, Xtro\ptafr, Xtro\galr2, Xtro\cysltr1, Xtro\LOC100125055, Xtro\gpr182, Xtro\kissr1b, Xtro\gpr25, Xtro\bdkrb2, Xtro\gpr19, Xtro\ltb4r2, Xtro\nmur2, Xtro\npy5r, Xtro\hcrtr2, Xtro\galr1, Xtro\galr3" "Mmus\Nmur1, Mmus\Ackr4, Mmus\Cntn1, Mmus\Ffar4, Mmus\Kiss1r, Mmus\Cxcr1, Mmus\Ccr1l1, Mmus\Ccr3, Mmus\Ccr5, Mmus\Ccdc141, Mmus\Nmur2, Mmus\Cxcr2, Mmus\Gpr15, Mmus\Ccr7, Mmus\Cxcr6, Mmus\Cxcr5, Mmus\Gpr17, Mmus\Ccr6, Mmus\Cx3cr1, Mmus\Dcc, Mmus\Npy5r, Mmus\Ccr4, Mmus\Igsf9b, Mmus\Xcr1, Mmus\Ccr8, Mmus\Gpr19, Mmus\Ccr2, Mmus\Cxcr3, Mmus\Ccr9, Mmus\Ccrl2, Mmus\Ackr2, Mmus\Gnrhr, Mmus\Cmklr1, Mmus\Hcrtr1, Mmus\Cxcr4, Mmus\Ccr1, Mmus\Galr1, Mmus\Cysltr1, Mmus\Ptafr, Mmus\Hcrtr2, Mmus\Gpr25, Mmus\Cntn2, Mmus\Ackr3, Mmus\Neo1, Mmus\Ccr10, Mmus\Olfr1167, Mmus\Galr2" "Hsap\CXCR4, Hsap\CX3CR1, Hsap\CNTN2, Hsap\XCR1, Hsap\KISS1R, Hsap\CXCR1, Hsap\CXCR6, Hsap\NEO1, Hsap\GPR15, Hsap\CCR1, Hsap\GPR17, Hsap\CCR10, Hsap\CMKLR1, Hsap\CCR3, Hsap\ACKR3, Hsap\CCDC141, Hsap\CCRL2, Hsap\ACKR4, Hsap\FFAR4, Hsap\ACKR2, Hsap\F2RL2, Hsap\GALR1, Hsap\CCR9, Hsap\GALR2, Hsap\CNTN1, Hsap\CCR2, Hsap\BDKRB2, Hsap\CCR8, Hsap\CCR4, Hsap\GPR19, Hsap\CCR7, Hsap\GNRHR, Hsap\CXCR5, Hsap\CCR5, Hsap\GALR3, Hsap\CCR6, Hsap\CXCR3, Hsap\DCC, Hsap\CXCR2, Hsap\NMUR1, Hsap\HCRTR1, Hsap\IGSF9B, Hsap\NMUR2" FBgn0034262 swi2 swi2 http://flybase.org/reports/FBgn0034262 protein_coding_gene - pupariation ; GO:0035073 | inferred from sequence or structural similarity with UniProtKB:Q9W568 intracellular signal transduction ; GO:0035556 | inferred from sequence or structural similarity with UniProtKB:Q9W568 response to ecdysone ; GO:0035075 | inferred from sequence or structural similarity with UniProtKB:Q9W568 - "CG14485, swi2" "IPR032675:Leucine-rich repeat domain, L domain-like" CG14485 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-303k11.2, Drer\islr2, Drer\LOC564748" - Cele\slt-1 - "Mmus\Lrrn4, Mmus\Islr, Mmus\Islr2, Mmus\Lrrn4cl" "Hsap\LRRN4CL, Hsap\LRRN4, Hsap\ISLR2, Hsap\ISLR" viable FBgn0053769 CG33769 - http://flybase.org/reports/FBgn0053769 protein_coding_gene enzyme activator activity ; GO:0008047 | inferred from electronic annotation with InterPro:IPR028996 molecular_function ; GO:0003674 | no biological data available ganglioside catabolic process ; GO:0006689 | inferred from electronic annotation with InterPro:IPR028996 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14458, CG33769" "IPR010512:Protein of unknown function DUF1091, IPR028996:Ganglioside GM2 activator" CG33769 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262769 Su(E1)-C - http://flybase.org/reports/FBgn0262769 gene - - - Su(E1)-C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005203 l(3)bt lethal brain tumor http://flybase.org/reports/FBgn0005203 - gene - - - "l(2)brain tumor, l(3)bt" - - 11-Aug-17 DroID_v2017_08 - - - - - - "tumorigenic,lethal,heat sensitive" "embryonic/larval brain,heat sensitive" FBgn0020835 l(2)M7 Massachusetts 7 http://flybase.org/reports/FBgn0020835 - gene - - - l(2)M7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005262 l(3)SG82 lethal (3) SG82 http://flybase.org/reports/FBgn0005262 - gene - - - l(3)SG82 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0011108 l(1)Q69 lethal (1) Q69 http://flybase.org/reports/FBgn0011108 FBgn0010210 gene - - - l(1)Q69 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000424 de deacon http://flybase.org/reports/FBgn0000424 - gene - - - de - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,adult thorax,adult abdomen,eye" FBgn0005340 Rf-c Roof c http://flybase.org/reports/FBgn0005340 - gene - - - Rf-c - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0034543 galla-1 galla-1 http://flybase.org/reports/FBgn0034543 protein_coding_gene molecular_function ; GO:0003674 | no biological data available nuclear chromosome segregation ; GO:0098813 | inferred from mutant phenotype spindle microtubule ; GO:0005876 | inferred from direct assay "CG10404, Cg30152, FAM96a, CG30152, galla-1" IPR002744:Domain of unknown function DUF59 CG30152 11-Aug-17 DroID_v2017_08 "Drer\fam96b, Drer\fam96a" Scer\CIA2 Cele\F45G2.10 "Xtro\fam96a, Xtro\fam96b" "Mmus\Fam96b, Mmus\Fam96a" "Hsap\FAM96B, Hsap\FAM96A" "viable,lethal" FBgn0082332 HM804 HM804 http://flybase.org/reports/FBgn0082332 gene - - - HM804 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263906 l(3)F582 - http://flybase.org/reports/FBgn0263906 gene - - - l(3)F582 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0040949 CG13998 - http://flybase.org/reports/FBgn0040949 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from expression pattern inferred from genomic context chorion ; GO:0042600 | inferred from genomic context CG13998 - CG13998 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02330 K -0.295862336 -0.063338005 -0.046679701 0.558545054 0.021816116 1.749932245 FBgn0011893 tRNA:Lys-CTT-1-7 transfer RNA:Lysine-CTT 1-7 http://flybase.org/reports/FBgn0011893 "FBgn0003796, FBgn0011886, FBgn0050301, FBgn0060181" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "tRNA[Lys][[2]], AE002778.trna3-LysCTT, tRNA:K2, tRNA:K:CTT:AE002778-c, CR30301, tRNA:lys2:42Eb, tRNAlys, chr2R.trna90-LysCTT, tRNA-Lys-CTT-1-7, tRNA:Lys-CTT-1-7, tRNA:K2:42Eb, AAG" - CR30301 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069425 JJF024 JJF024 http://flybase.org/reports/FBgn0069425 gene - - - JJF024 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0053496 CR33496 - http://flybase.org/reports/FBgn0053496 pseudogene_attribute - - - "CG33496, CR33496" - CR33496 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003523 Ste Stellate http://flybase.org/reports/FBgn0003523 FBgn0063181 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from sequence or structural similarity protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | traceable author statement spermatogenesis ; GO:0007283 | inferred from genetic interaction with Su(Ste) regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay "CG32605, Ste eu, eSte, ste, BcDNA:GM31840, Ste, euSte" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" spermatocyte FBgn0031052 CG14215 - http://flybase.org/reports/FBgn0031052 protein_coding_gene - nuclear pore complex assembly ; GO:0051292 | inferred from biological aspect of ancestor with PANTHER:PTN001854329 nuclear periphery ; GO:0034399 | inferred from biological aspect of ancestor with PANTHER:PTN001854329 "CG14215, ELYS" "IPR025151:ELYS-like domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG14215 11-Aug-17 DroID_v2017_08 Drer\ahctf1 - Cele\mel-28 Xtro\ahctf1 Mmus\Ahctf1 Hsap\AHCTF1 "viable,fertile" FBgn0262323 mir-252 mir-252 stem loop http://flybase.org/reports/FBgn0262323 miRNA_gene - muscle organ development ; GO:0007517 | inferred from mutant phenotype - "miR-252, dme-mir-252, mir-252, 252, MIR-252, CR43030, dme-miR-252, dme-miR-252-5p" - CR43030 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible" "eye,wing,wing vein,wing vein L5,wing margin,wing margin bristle" FBgn0010357 betaTry betaTrypsin http://flybase.org/reports/FBgn0010357 FBgn0033622 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "CG18211, SP119, Try, DmBetaTry, beta, betaTry" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG18211 11-Aug-17 DroID_v2017_08 "Drer\zgc:112038, Drer\prss60.3, Drer\prss60.1, Drer\zgc:153968, Drer\LOC562139, Drer\zgc:123295, Drer\zgc:92590, Drer\try, Drer\si:ch211-165b19.9, Drer\prss60.2, Drer\zgc:112160, Drer\tmprss4b, Drer\si:dkeyp-93a5.2, Drer\zgc:163079, Drer\zgc:55888, Drer\ctrl" - "Cele\try-1, Cele\rab-11.1" - "Mmus\Try4, Mmus\Klk1b5, Mmus\Prss36, Mmus\Prss2, Mmus\2210010C04Rik, Mmus\Gm10334, Mmus\Prss34, Mmus\Prss1, Mmus\Prss3, Mmus\Gm5771, Mmus\Try10, Mmus\Prss53, Mmus\Prss55" "Hsap\PRSS36, Hsap\PRSS22, Hsap\PRSS33, Hsap\PRSS45, Hsap\PRSS53, Hsap\PRSS3, Hsap\PRSS8, Hsap\KLK15, Hsap\PRSS27, Hsap\TPSG1, Hsap\PRSS38, Hsap\PRSS1" " larval stage | third instar , adult stage " larval digestive system | restricted

viable FBgn0058203 CG40203 - http://flybase.org/reports/FBgn0058203 protein_coding_gene - - - CG40203 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028574 pp45 pp45 http://flybase.org/reports/FBgn0028574 gene - - - pp45 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000400 cvw convexwing http://flybase.org/reports/FBgn0000400 - gene - - - cvw - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" "wing,tergite,female,microchaeta & adult abdomen | female" FBgn0264974 rho::ru - http://flybase.org/reports/FBgn0264974 engineered_fusion_gene - - - rho::ru - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001757 l(1)M5 lethal (1) M5 http://flybase.org/reports/FBgn0001757 - gene - - - l(1)M5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039659 CG14506 - http://flybase.org/reports/FBgn0039659 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg14506, CG14506" IPR000504:RNA recognition motif domain CG14506 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0029526 CR18166 - http://flybase.org/reports/FBgn0029526 pseudogene_attribute - - - "CG13372, BEST:GH02584, CR18166, CG18166" - CR18166 11-Aug-17 DroID_v2017_08 - - - - - - DRSC17249 E -1.374136868 0.977437101 1.78543844 -0.156882764 -0.079455441 -0.104201653 FBgn0259737 CG42391 - http://flybase.org/reports/FBgn0259737 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42391 - CG42391 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-272n13.3, Drer\zgc:85936" - "Cele\lem-3, Cele\F44E5.15, Cele\K07D4.2" Xtro\ankle1 "Mmus\Ankrd36, Mmus\Ankrd26, Mmus\Ccdc144b, Mmus\4932414N04Rik, Mmus\4921524L21Rik, Mmus\Ankrd7, Mmus\Ankle1" "Hsap\ANKLE1, Hsap\ANKRD30A, Hsap\ANKRD18A, Hsap\ANKRD18B, Hsap\ANKRD20A1, Hsap\ANKRD26, Hsap\ANKRD20A4, Hsap\ANKRD62, Hsap\ANKRD20A2, Hsap\ANKRD30B, Hsap\ANKRD20A3" FBgn0264902 CR44093 - http://flybase.org/reports/FBgn0264902 non_protein_coding_gene - - - CR44093 - CR44093 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031621 Elba3 Early boundary activity 3 http://flybase.org/reports/FBgn0031621 protein_coding_gene "protein binding, bridging ; GO:0030674 | inferred from direct assay" positive regulation of chromatin silencing ; GO:0031937 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay chromatin silencing complex ; GO:0005677 | inferred from direct assay "Elba3, CG15634, Elba" - CG15634 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001541 l(1)14DEc lethal (1) 14DEc http://flybase.org/reports/FBgn0001541 - gene - - - l(1)14DEc - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028351 l(1)G0167 lethal (1) G0167 http://flybase.org/reports/FBgn0028351 gene - - - l(1)G0167 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0023081 gek genghis khan http://flybase.org/reports/FBgn0023081 "FBgn0010655, FBgn0044829, FBgn0061181" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR014930, InterPro:IPR017441, InterPro:IPR017892 protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR000961, InterPro:IPR014930, InterPro:IPR017892 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40793 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR014930, InterPro:IPR017892 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 synaptic target recognition ; GO:0008039 | inferred from mutant phenotype actin polymerization or depolymerization ; GO:0008154 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | non-traceable author statement" axon ; GO:0030424 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay "MRCKalpha, CG4012, dMRCK, l(2)09373, Gek, anon-WO0200864.1, Mrck, MdaPk, gek, MRCK" "IPR000095:CRIB domain, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR001180:Citron homology (CNH) domain, IPR001849:Pleckstrin homology domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR014930:Myotonic dystrophy protein kinase, coiled coil, IPR017441:Protein kinase, ATP binding site, IPR011993:PH domain-like, IPR017892:Protein kinase, C-terminal, IPR031597:KELK-motif containing domain" CG4012 11-Aug-17 DroID_v2017_08 "Drer\LOC100333880, Drer\rock2b, Drer\rock1, Drer\cdc42bpb, Drer\rock2a, Drer\cita, Drer\cdc42bpaa, Drer\si:ch211-89p3.3" "Scer\GIN4, Scer\CBK1, Scer\BZZ1" "Cele\let-502, Cele\W02B8.2, Cele\F59A6.5, Cele\mrck-1" "Xtro\rock2, Xtro\cit, Xtro\cdc42bpb, Xtro\rock1, Xtro\cdc42bpa" "Mmus\Rock2, Mmus\Cdc42bpg, Mmus\Rock1, Mmus\Cit, Mmus\Cdc42bpb, Mmus\Cdc42bpa, Mmus\Dmpk" "Hsap\MKNK2, Hsap\DMPK, Hsap\ROCK2, Hsap\CDC42BPA, Hsap\CDC42BPB, Hsap\CIT, Hsap\DCLK3, Hsap\ROCK1, Hsap\BRSK2, Hsap\CDC42BPG, Hsap\BRSK1" "neuroanatomy defective,recessive,somatic clone,viable,visible,fertile,lethal,maternal effect,wild-type,lethal - all die before end of larval stage,some die during larval stage" "eye photoreceptor cell,somatic clone,lamina plexus,lamina,growth cone,eye,embryonic/larval optic stalk,photoreceptor cell R7,eye photoreceptor cell | third instar larval stage,embryonic/larval optic stalk | third instar larval stage,lamina | third instar larval stage,eye | adult stage,embryonic/first instar larval cuticle,maternal effect" FBgn0000019 abr abero http://flybase.org/reports/FBgn0000019 - gene - - - abr - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,poor,visible,recessive" "ommatidium,abdomen,macrochaeta,microchaeta,wing,anterior dorsocentral bristle" FBgn0019809 gcm2 gcm2 http://flybase.org/reports/FBgn0019809 FBgn0032133 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003902 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003902 glial cell differentiation ; GO:0010001 | inferred from expression pattern plasmatocyte differentiation ; GO:0042387 | traceable author statement glial cell development ; GO:0021782 | inferred from mutant phenotype neuron differentiation ; GO:0030182 | inferred from mutant phenotype plasmatocyte differentiation ; GO:0042387 | inferred from expression pattern negative regulation of crystal cell differentiation ; GO:0042690 | inferred from mutant phenotype glial cell differentiation ; GO:0010001 | inferred from mutant phenotype hemocyte differentiation ; GO:0042386 | inferred from expression pattern embryonic crystal cell differentiation ; GO:0035165 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype embryonic plasmatocyte differentiation ; GO:0035164 | traceable author statement" nucleus ; GO:0005634 | non-traceable author statement "dGCM2, CG3858, gcm2, Gcm2, FBgn0019809, GCM-2" IPR003902:Transcription regulator GCM domain CG3858 11-Aug-17 DroID_v2017_08 Drer\gcm2 - - "Xtro\gcm1, Xtro\gcm2" "Mmus\Gcm2, Mmus\Gcm1" "Hsap\GCM2, Hsap\GCM1" " embryonic stage | stage 12-15 , embryonic stage | stage 5-11 , embryonic stage | stage 9-11 " " lateral ectoderm

, head mesoderm

, CNS glial cell | subset

, interface glial cell

, neuroblast NB1-3

" "neuroanatomy defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "dorsal multidendritic neuron ddaD,abdominal ventral multidendritic neuron v'dap,crystal cell primordium,crystal cell,embryonic/larval glial cell,ectopic,glial cell,outer photoreceptor cell,somatic clone,optic lobe,medulla cortex & glial cell | somatic clone" FBgn0053666 CG33666 - http://flybase.org/reports/FBgn0053666 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33666 - CG33666 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262568 CG43108 - http://flybase.org/reports/FBgn0262568 protein_coding_gene - - - "CG43108, lincRNA.338" - CG43108 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069429 JJF007 JJF007 http://flybase.org/reports/FBgn0069429 gene - - - JJF007 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0065514 l(2)SH1156 lethal (2) SH1156 http://flybase.org/reports/FBgn0065514 gene - - - "l(2)SH1156, l(2)SH2 1156" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000069 Alp Abnormal leg pattern http://flybase.org/reports/FBgn0000069 - gene - - - Alp - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,sex comb,metatarsus,tarsal segment 2" FBgn0261940 robo1::robo2 - http://flybase.org/reports/FBgn0261940 engineered_fusion_gene - - - "Robo1:2, Robo2:1, robo::lea, robo1::robo2" - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "longitudinal connective,tract,ectopic | embryonic stage" FBgn0039413 CG14556 - http://flybase.org/reports/FBgn0039413 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14556 IPR031883:Protein of unknown function DUF4763 CG14556 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267008 CR45452 - http://flybase.org/reports/FBgn0267008 non_protein_coding_gene - - - CR45452 - CR45452 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263118 tx taxi http://flybase.org/reports/FBgn0263118 protein_coding_gene "bHLH transcription factor binding ; GO:0043425 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with da inferred by curator from GO:0043425,GO:0070888 E-box binding ; GO:0070888 | contributes_to inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from direct assay" "somatic muscle development ; GO:0007525 | traceable author statement imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype muscle attachment ; GO:0016203 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with da mesoderm development ; GO:0007498 | inferred from expression pattern regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from expression pattern cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype" - "dei, tx, del, CG5441, Delilah, delilah, bHLHc10, Dei" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR032665:Helix-loop-helix protein delilah" CG5441 11-Aug-17 DroID_v2017_08 "Drer\mespaa, Drer\msgn1, Drer\atoh7, Drer\atoh1b, Drer\atoh1c, Drer\mespba, Drer\mespab, Drer\atoh1a" - "Cele\ngn-1, Cele\hlh-16" "Xtro\mespb, Xtro\mespa, Xtro\atoh7, Xtro\atoh1, Xtro\msgn1" "Mmus\Olig3, Mmus\Msgn1, Mmus\Olig2, Mmus\Olig1, Mmus\Atoh7, Mmus\Atoh1, Mmus\Mesp2, Mmus\Mesp1" "Hsap\MSGN1, Hsap\MESP1, Hsap\MESP2, Hsap\TCF3, Hsap\ATOH7, Hsap\ATOH1" DRSC16931 E 0.489344248 0.145368523 2.07876987 -0.764703101 0.402146852 0.5388644 FBgn0034159 CG15615 - http://flybase.org/reports/FBgn0034159 protein_coding_gene - - - CG15615 "IPR009078:Ferritin-like superfamily, IPR032134:Protein of unknown function DUF4816" CG15615 11-Aug-17 DroID_v2017_08 - - - - - - DRSC06568 I 0.521183675 -2.149566102 0.391009478 -0.426665101 0.129843834 -0.578738269 FBgn0052549 CG32549 - http://flybase.org/reports/FBgn0052549 protein_coding_gene 5'-nucleotidase activity ; GO:0008253 | inferred from biological aspect of ancestor with PANTHER:PTN000250728 - - "CG6278, CG6267, CG6247, CG32549, 45555998, 45555989, 24643014, 24643016" "IPR008380:HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase, IPR016695:Purine 5'-nucleotidase, IPR023214:HAD-like domain" CG32549 11-Aug-17 DroID_v2017_08 "Drer\nt5c2b, Drer\nt5dc1, Drer\nt5c2a, Drer\nt5c2l1" - Cele\Y71H10B.1 "Xtro\nt5c2, Xtro\nt5dc4, Xtro\abhd10" "Mmus\Nt5c2, Mmus\Nt5dc1" "Hsap\NT5C2, Hsap\NT5DC1, Hsap\NT5DC4" "viable,fertile" FBgn0029651 CG10782 - http://flybase.org/reports/FBgn0029651 protein_coding_gene - - - CG10782 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001310 kk kinky http://flybase.org/reports/FBgn0001310 - gene - - - kk - - 11-Aug-17 DroID_v2017_08 - - - - - - visible macrochaeta FBgn0260944 Rbp1 RNA-binding protein 1 http://flybase.org/reports/FBgn0260944 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Trn-SR mRNA binding ; GO:0003729 | inferred from direct assay "regulation of mRNA 3'-end processing ; GO:0031440 | inferred from mutant phenotype regulation of transcriptional start site selection at RNA polymerase II promoter ; GO:0001178 | inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from direct assay regulation of gene expression ; GO:0010468 | inferred from mutant phenotype" transcriptionally active chromatin ; GO:0035327 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "RBP1, CG17136, rbp1, RRM1, Rbp-1, rrm1, Rbp1, RRM11, rrm11, Rbp11, Rbp1D" IPR000504:RNA recognition motif domain CG17136 11-Aug-17 DroID_v2017_08 "Drer\srsf3b, Drer\srsf7b, Drer\srsf3a, Drer\srsf7a" Scer\NPL3 "Cele\Y57G11A.5, Cele\rsp-6" "Xtro\srsf7, Xtro\srsf3" "Mmus\Srsf7, Mmus\Srsf3" "Hsap\SRSF3, Hsap\SRSF7" " adult stage , larval stage | third instar , embryonic stage -- adult stage , pupal stage " FBgn0065671 l(2)SH0682 lethal (2) SH0682 http://flybase.org/reports/FBgn0065671 gene - - - "l(2)SH0682, l(2)SH2 0682" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067338 mir-60 mir-60 http://flybase.org/reports/FBgn0067338 miRNA_gene - - - "miR-60, mir-60" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267895 CR46183 - http://flybase.org/reports/FBgn0267895 pseudogene_attribute - - - "CR46183, CG12717-related" - CR46183 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011279 Obp69a Odorant-binding protein 69a http://flybase.org/reports/FBgn0011279 - protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush phenylalkylamine binding ; GO:0008145 | inferred from sequence or structural similarity pheromone binding ; GO:0005550 | inferred from sequence or structural similarity odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "Obp69a, PBPRP-1, 69a, PBP1, pbprp1, PB-PRP1, pbprp-1, CG10436, DmelObp69a, Pbprp1" IPR006170:Pheromone/general odorant binding protein CG10436 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " sensillum trichodeum of antennal segment 3

, antennal segment 3 | anterior

" viable embryonic/larval hemocyte | third instar larval stage FBgn0011627 l(2)T56j7 lethal (2) T56j7 http://flybase.org/reports/FBgn0011627 FBgn0005177 gene - - - l(2)T56j7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0053052 CG33052 - http://flybase.org/reports/FBgn0053052 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3882, CG33052" IPR007033:RAB6-interacting golgin CG33052 11-Aug-17 DroID_v2017_08 Drer\gorab - - Xtro\gorab Mmus\Gorab Hsap\GORAB viable FBgn0001269 inv invected http://flybase.org/reports/FBgn0001269 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | inferred from genetic interaction with en, gsb inferred from genetic interaction with en, gsb, ptc defense response to fungus ; GO:0050832 | inferred from mutant phenotype compartment pattern specification ; GO:0007386 | traceable author statement wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR000747 "inv, CG17835, Engrailed/Invected, in, er, IV, Inv, INV" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR000747:Homeobox domain engrailed, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR019549:Homeobox engrailed, C-terminal, IPR019737:Homeobox engrailed-type, conserved site, IPR020479:Homeobox domain, metazoa" CG17835 11-Aug-17 DroID_v2017_08 "Drer\eng2b, Drer\eng2a, Drer\eng1b, Drer\eng1a" Scer\RSC58 "Cele\ceh-58, Cele\ceh-41, Cele\ceh-16" "Xtro\en2, Xtro\en1" "Mmus\Cphx1, Mmus\Cphx2, Mmus\Cphx3, Mmus\En1, Mmus\En2" "Hsap\EN1, Hsap\EN2" " embryonic stage | contracted germ band , embryonic stage | extended germ band , embryonic stage | stage 13 , larval stage | third instar " " inclusive hindgut primordium

, organism | segmentally repeated

,organism | segmentally repeated & posterior compartment , dorsal mesothoracic disc | posterior compartment

" "visible,dominant,immune response defective,viable,homeotic,heat sensitive" "wing,segment,cuticle,denticle belt,wing vein,ectopic,anterior/posterior compartment boundary,longitudinal connective,commissure,presumptive embryonic/larval muscle system,embryonic hindgut,anterior crossvein,wing vein L1,wing vein L2,anterior" FBgn0052690 CR32690 - http://flybase.org/reports/FBgn0052690 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:LP10814, CG32690, CR32690" - CR32690 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036829 Ir75d Ionotropic receptor 75d http://flybase.org/reports/FBgn0036829 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir75d, CT33663, IR75d, CG14076, DmelIR75d, lr75d" IPR001320:Ionotropic glutamate receptor CG14076 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-183j2.10, Drer\grik4, Drer\grik1b, Drer\si:ch211-251b21.1, Drer\grik1a" - "Cele\glr-8, Cele\glr-5, Cele\glr-4" - "Mmus\Grik1, Mmus\Grik4" "Hsap\GRIK4, Hsap\GRIK1" "partially lethal - majority die,some die during pupal stage,viable" FBgn0040373 CG3038 - http://flybase.org/reports/FBgn0040373 protein_coding_gene "galactosyltransferase activity ; GO:0008378 | inferred from electronic annotation with InterPro:IPR002659 transferase activity, transferring glycosyl groups ; GO:0016757 | inferred from sequence or structural similarity with EMBL:Y15062" protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR002659 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "EG:BACR37P7.1, CG3038, dbeta3GnT, GalT3" "IPR002659:Glycosyl transferase, family 31" CG3038 11-Aug-17 DroID_v2017_08 "Drer\b3gnt2b, Drer\b3gnt9, Drer\b3galt4, Drer\b3gnt7, Drer\zgc:86586, Drer\LOC565422, Drer\si:ch211-126g16.11, Drer\si:ch211-126g16.10, Drer\b3gnt2l, Drer\b3gnt2a, Drer\b3galt2, Drer\b3gnt3, Drer\si:dkey-175m17.6, Drer\b3galt1a, Drer\zgc:194551, Drer\b3galnt2, Drer\b3gnt5b, Drer\b3galt1b, Drer\LOC100535930, Drer\b3gnt5a, Drer\b3gnt7l, Drer\si:dkey-160o24.3, Drer\zgc:194330" - "Cele\C47F8.3, Cele\C47F8.5, Cele\T09F5.1, Cele\B0024.3, Cele\F14B6.6, Cele\C47F8.6, Cele\E03H4.11, Cele\T15D6.5, Cele\C54C8.3, Cele\F48F7.3, Cele\F14B6.4, Cele\bre-2, Cele\T09E11.10, Cele\bre-5, Cele\B0024.15" "Xtro\b3galnt2, Xtro\b3gnt3, Xtro\LOC100489267, Xtro\b3gnt3, Xtro\b3gnt2, Xtro\LOC100494986, Xtro\LOC100494668, Xtro\b3galt4, Xtro\b3galt1, Xtro\b3gnt6, Xtro\LOC100493833, Xtro\b3galt2, Xtro\LOC100487553, Xtro\b3gnt4, Xtro\b3gnt5" "Mmus\B3gnt8, Mmus\B3galt2, Mmus\B3galt5, Mmus\B3galnt1, Mmus\B3gnt3, Mmus\B3gnt6, Mmus\B3galt1, Mmus\B3galt4, Mmus\B3gnt9, Mmus\B3gnt5, Mmus\B3gnt7, Mmus\B3gnt4, Mmus\B3galnt2, Mmus\B3gnt2" "Hsap\B3GNT8, Hsap\B3GNT9, Hsap\B3GNT3, Hsap\B3GALNT1, Hsap\B3GALT1, Hsap\B3GNT4, Hsap\B3GNT7, Hsap\B3GNT5, Hsap\B3GALT4, Hsap\B3GNT2, Hsap\B3GALT2, Hsap\B3GALNT2, Hsap\B3GALT5, Hsap\B3GNT6" "viable,fertile" FBgn0034284 CG14491 - http://flybase.org/reports/FBgn0034284 protein_coding_gene - - - CG14491 IPR010512:Protein of unknown function DUF1091 CG14491 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045057 fs(1)164 female sterile (1) 164 http://flybase.org/reports/FBgn0045057 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)164 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "nurse cell & nucleus,egg chamber" FBgn0035956 Doc2 Dorsocross2 http://flybase.org/reports/FBgn0035956 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" cardiocyte differentiation ; GO:0035051 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Dm-DOC2, CG5187, Doc2, doc2, Doc" "IPR001699:Transcription factor, T-box, IPR002070:Transcription factor, Brachyury, IPR008967:p53-like transcription factor, DNA-binding, IPR018186:Transcription factor, T-box, conserved site" CG5187 11-Aug-17 DroID_v2017_08 "Drer\tbx4, Drer\tb, Drer\tbx19, Drer\tbx21, Drer\tbx18, Drer\mgaa, Drer\tbx20, Drer\tbr1a, Drer\tbx5a, Drer\tbx1, Drer\tbx6, Drer\tbx2a, Drer\tbx6l, Drer\tbx22, Drer\tbx3a, Drer\eomesb, Drer\tbx5b, Drer\eomesa, Drer\tbx16, Drer\tbx3b, Drer\ta, Drer\tbr1b, Drer\tbx2b" - "Cele\mls-1, Cele\mab-9, Cele\tbx-2" "Xtro\tbx4, Xtro\tbx2, Xtro\tbx3, Xtro\tbx20, Xtro\t2, Xtro\eomes, Xtro\tbx1, Xtro\tbx6, Xtro\tbx22, Xtro\tbr1, Xtro\mga, Xtro\vegt, Xtro\t, Xtro\tbx5, Xtro\tbx18" "Mmus\Tbx6, Mmus\Tbr1, Mmus\Tbx5, Mmus\Tbx19, Mmus\Tbx22, Mmus\Tbx18, Mmus\Eomes, Mmus\Tbx4, Mmus\T, Mmus\Tbx3, Mmus\Tbx2, Mmus\Tbx10, Mmus\Tbx21, Mmus\Tbx15, Mmus\Tbx20, Mmus\Mga, Mmus\Tbx1" "Hsap\TBX2, Hsap\TBX10, Hsap\MGA, Hsap\T, Hsap\TBX20, Hsap\TBX21, Hsap\TBX18, Hsap\TBX19, Hsap\TBX6, Hsap\TBX5, Hsap\TBX22, Hsap\TBX3, Hsap\TBX15, Hsap\TBX1, Hsap\EOMES, Hsap\TBX4, Hsap\TBR1" embryonic stage--pupal stage " embryonic stage , embryonic stage | stage 9-16 , embryonic stage | stage 15-16 , embryonic stage | stage 5-15 , embryonic stage | stage 5-11 " " cardioblast | subset

, parasegment && ectoderm && mesoderm | dorsal & restricted

, embryonic anterior Malpighian tubule

, amnioserosa

, organism | dorso-lateral

, abdominal lateral pentascolopidial chordotonal organ lch5

, mesoderm | restricted

, dorsal pouch

, procephalic neurogenic region

" "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,viable" "wing vein,ectopic,wing,extended germ band embryo,embryonic pericardial cell,cardioblast,supernumerary,somatic mesoderm,distal,leg,arista" FBgn0051809 CG31809 - http://flybase.org/reports/FBgn0051809 protein_coding_gene - - - CG31809 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG31809 11-Aug-17 DroID_v2017_08 "Drer\hsd17b12a, Drer\hsd17b12b, Drer\hsdl1, Drer\hsd20b2, Drer\hsd17b3" Scer\IFA38 "Cele\dhs-5, Cele\stdh-4, Cele\stdh-1, Cele\dhs-27, Cele\stdh-3, Cele\let-767, Cele\stdh-2" "Xtro\LOC100497556, Xtro\hsd17b12, Xtro\hsdl1" "Mmus\Hsd17b3, Mmus\Hsdl1, Mmus\Hsd17b12" "Hsap\HSDL1, Hsap\HSD17B3, Hsap\HSD17B12" FBgn0038530 AttD Attacin-D http://flybase.org/reports/FBgn0038530 protein_coding_gene - defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern "extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR005520, InterPro:IPR005521 SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay" "AttD, Att, CG7629, att, attD, att D, Attacin D" "IPR005520:Attacin, N-terminal, IPR005521:Attacin, C-terminal" CG7629 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038930 CG5778 - http://flybase.org/reports/FBgn0038930 protein_coding_gene - - - "CT18134, BcDNA:GH13168, CG5778" - CG5778 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040116 l(2)23Da lethal (2) 23Da http://flybase.org/reports/FBgn0040116 gene - - - l(2)23Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062667 EP3087 EP3087 http://flybase.org/reports/FBgn0062667 gene - - - "EP(3)3087, EP3087" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038135 CG8773 - http://flybase.org/reports/FBgn0038135 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 dsRNA transport ; GO:0033227 | inferred from mutant phenotype peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 CG8773 "IPR024571:ERAP1-like C-terminal domain, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR034016:Aminopeptidase N-type" CG8773 11-Aug-17 DroID_v2017_08 "Drer\lnpep, Drer\si:ch211-198g19.1, Drer\erap1a, Drer\si:ch211-149p5.1, Drer\enpep, Drer\anpepb, Drer\erap2, Drer\erap1b, Drer\npepps, Drer\si:ch211-276a23.5, Drer\anpepa, Drer\si:ch211-106j24.1" "Scer\APE2, Scer\TMA108, Scer\AAP1" "Cele\T12E12.6, Cele\VB0395L.1, Cele\F49B2.6, Cele\pam-1, Cele\T07F10.1, Cele\Y42A5A.1, Cele\AC3.5, Cele\mnp-1, Cele\T16G12.1, Cele\Y67D8C.9, Cele\R03G8.4, Cele\Y53F4B.20, Cele\R03G8.6" "Xtro\erap1, Xtro\enpep, Xtro\npepps, Xtro\lvrn, Xtro\lnpep, Xtro\anpep" "Mmus\Enpep, Mmus\Trhde, Mmus\Erap1, Mmus\Npepps, Mmus\Lvrn, Mmus\Lnpep, Mmus\Anpep" "Hsap\ERAP1, Hsap\ENPEP, Hsap\ANPEP, Hsap\TRHDE, Hsap\LNPEP, Hsap\NPEPPS, Hsap\LVRN, Hsap\ERAP2" viable FBgn0028920 CG8997 - http://flybase.org/reports/FBgn0028920 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT25774, DS00941.12, BG:DS00941.12, CG8997" IPR010562:Haemolymph juvenile hormone binding CG8997 11-Aug-17 DroID_v2017_08 - - Cele\fbxa-14 - - - viable FBgn0050120 CG30120 - http://flybase.org/reports/FBgn0050120 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30120 - CG30120 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038188 Art9 Arginine methyltransferase 9 http://flybase.org/reports/FBgn0038188 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR025799 peptidyl-arginine methylation ; GO:0018216 | inferred from sequence or structural similarity with HGNC:5187 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:5187 "DART9, CG9929, Art9" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR025799:Protein arginine N-methyltransferase" CG9929 11-Aug-17 DroID_v2017_08 "Drer\LOC556054, Drer\prmt6, Drer\prmt1, Drer\prmt8b, Drer\prmt3" Scer\HMT1 Cele\prmt-1 "Xtro\prmt6, Xtro\prmt8, Xtro\prmt1, Xtro\prmt3" "Mmus\Prmt3, Mmus\Prmt2, Mmus\Prmt6, Mmus\Prmt1, Mmus\Prmt8" "Hsap\PRMT1, Hsap\PRMT3, Hsap\PRMT8, Hsap\PRMT2, Hsap\PRMT6" viable FBgn0001669 l(1)EN5 lethal (1) from Eugene Nonautonomous 5 http://flybase.org/reports/FBgn0001669 - gene - - - l(1)EN5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0016679 Mab3C7 Monoclonal antibody 3C7 http://flybase.org/reports/FBgn0016679 - gene - - - Mab3C7 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005330 P48 P48 http://flybase.org/reports/FBgn0005330 - gene - - - P48 - - 11-Aug-17 DroID_v2017_08 - - - - - - optomotor response defective FBgn0039944 CG17162 - http://flybase.org/reports/FBgn0039944 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG40460, anon-20Ea, CG17162, FBgn0058460" - CG17162 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013552 l(3)ry119 lethal (3) ry119 http://flybase.org/reports/FBgn0013552 - gene - - - "l(3)119, l(3)ry119" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,partially lethal - majority die,lethal" eye FBgn0031651 mRpL24 mitochondrial ribosomal protein L24 http://flybase.org/reports/FBgn0031651 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR003256, InterPro:IPR005825 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR003256, InterPro:IPR005825 translation ; GO:0006412 | inferred from sequence or structural similarity mitochondrial translation ; GO:0032543 | traceable author statement" mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q96A35 "L24, CG8849, mRpL24, RpL24" "IPR003256:Ribosomal protein L24, IPR005824:KOW, IPR005825:Ribosomal protein L24/L26, conserved site, IPR008991:Translation protein SH3-like domain, IPR014722:Ribosomal protein L2 domain 2" CG8849 11-Aug-17 DroID_v2017_08 Drer\mrpl24 Scer\MRPL40 Cele\mrpl-24 Xtro\mrpl24 Mmus\Mrpl24 Hsap\MRPL24 "viable,visible" trichogen cell FBgn0037786 CG5361 - http://flybase.org/reports/FBgn0037786 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from electronic annotation with InterPro:IPR001952 "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR001952, InterPro:IPR017849, InterPro:IPR017850 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available CG5361 "IPR001952:Alkaline phosphatase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG5361 11-Aug-17 DroID_v2017_08 "Drer\alpi.1, Drer\alp3, Drer\alpi.2, Drer\alpl" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1" "Mmus\Alpl, Mmus\Akp3, Mmus\Alpi, Mmus\Alppl2" "Hsap\ALPP, Hsap\ALPL, Hsap\ALPPL2, Hsap\ALPI" FBgn0036765 CG7408 - http://flybase.org/reports/FBgn0036765 protein_coding_gene sulfuric ester hydrolase activity ; GO:0008484 | inferred from electronic annotation with InterPro:IPR000917 "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype" - CG7408 "IPR000917:Sulfatase, N-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site" CG7408 11-Aug-17 DroID_v2017_08 "Drer\arsa, Drer\LOC559800, Drer\ids, Drer\LOC563783, Drer\arsg, Drer\galns, Drer\si:dkey-174i8.1, Drer\arsh, Drer\LOC101884179, Drer\sgsh, Drer\arsia" - Cele\sul-3 "Xtro\arsb, Xtro\sts, Xtro\ids, Xtro\arsi, Xtro\arsh, Xtro\sgsh, Xtro\arsd, Xtro\arsk, Xtro\arsj, Xtro\arsa.1" "Mmus\Sgsh, Mmus\Arsb, Mmus\Arsj, Mmus\Arsi, Mmus\Arsg, Mmus\Ids, Mmus\Arsa, Mmus\Sulf1, Mmus\Galns" "Hsap\ARSE, Hsap\ARSA, Hsap\SGSH, Hsap\GALNS, Hsap\ARSI, Hsap\ARSG, Hsap\ARSJ, Hsap\SULF1, Hsap\ARSH, Hsap\ARSD, Hsap\IDS, Hsap\ARSB, Hsap\STS, Hsap\ARSF" "viable,fertile" FBgn0050046 CG30046 - http://flybase.org/reports/FBgn0050046 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CT39323, CG17740, CG30046" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR002861:Reeler domain, IPR009465:Spondin, N-terminal, IPR002223:Pancreatic trypsin inhibitor Kunitz domain" CG30046 11-Aug-17 DroID_v2017_08 "Drer\thsd7ba, Drer\thsd7aa, Drer\spon1a, Drer\thsd7bb, Drer\spon1b" - Cele\spon-1 "Xtro\thsd7a, Xtro\thsd7b, Xtro\spon1" "Mmus\Spon1, Mmus\Thsd7a, Mmus\Thsd7b" "Hsap\THSD7A, Hsap\SPON1, Hsap\THSD7B" viable FBgn0034921 DCP1 Decapping protein 1 http://flybase.org/reports/FBgn0034921 protein_coding_gene enzyme activator activity ; GO:0008047 | inferred from electronic annotation with InterPro:IPR010334 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI2 m7G(5')pppN diphosphatase activity ; GO:0050072 | NOT inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VKK1 mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000418281 enzyme regulator activity ; GO:0030234 | inferred from biological aspect of ancestor with PANTHER:PTN000418281 "positive regulation of catalytic activity ; GO:0043085 | inferred from electronic annotation with InterPro:IPR010334 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | NOT inferred from mutant phenotype deadenylation-independent decapping of nuclear-transcribed mRNA ; GO:0031087 | inferred from biological aspect of ancestor with PANTHER:PTN000418281 deadenylation-dependent decapping of nuclear-transcribed mRNA ; GO:0000290 | inferred from biological aspect of ancestor with PANTHER:PTN000418281 positive regulation of gene silencing by miRNA ; GO:2000637 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype regulation of cytoplasmic mRNA processing body assembly ; GO:0010603 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay "dDcp1, CG11183, anon-WO0118547.163, Dcp1, DCP1, Dcp1p, Dcp-1, dDCP1" "IPR010334:mRNA-decapping enzyme subunit 1, IPR011993:PH domain-like, IPR031953:mRNA-decapping enzyme, C-terminal" CG11183 11-Aug-17 DroID_v2017_08 "Drer\dcp1b, Drer\dcp1a" Scer\DCP1 Cele\dcap-1 "Xtro\dcp1b, Xtro\dcp1a" "Mmus\Dcp1a, Mmus\Dcp1b" "Hsap\DCP1A, Hsap\DCP1B" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,germline clone,maternal effect,female sterile,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "egg chamber,germline clone,cytoplasmic mRNA processing body, with DCP1tT2.R57A,embryonic abdominal segment,maternal effect,embryo,anterior,pole cell,cytoplasmic mRNA processing body, with DCP1442P" DRSC04091 K 0.69075801 0.550145052 0.586366348 -0.336515974 -1.968295973 -0.020591001 FBgn0065810 l(2)SH0386 lethal (2) SH0386 http://flybase.org/reports/FBgn0065810 gene - - - "l(2)SH0386, l(2)SH2 0386" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010157 logo longitudinal gone http://flybase.org/reports/FBgn0010157 - gene - - - logo - - 11-Aug-17 DroID_v2017_08 - - - - - - longitudinal connective FBgn0263414 CR43460 - http://flybase.org/reports/FBgn0263414 non_protein_coding_gene - - - CR43460 - CR43460 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065173 l(3)SH019 lethal (3) SH019 http://flybase.org/reports/FBgn0065173 gene - - - "l(3)SH019, l(2)SH3 019" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065524 l(2)SH1121 lethal (2) SH1121 http://flybase.org/reports/FBgn0065524 gene - - - "l(2)SH1121, l(2)SH2 1121" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005002 Cyd Curlyoid http://flybase.org/reports/FBgn0005002 - gene - - - Cyd - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" wing FBgn0005110 Humeral-patch Humeral patch http://flybase.org/reports/FBgn0005110 - gene - - - "Hup, Humeral-patch" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259466 EP-610 - http://flybase.org/reports/FBgn0259466 gene - - - EP-610 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,chaeta" FBgn0065633 l(2)SH0775 lethal (2) SH0775 http://flybase.org/reports/FBgn0065633 gene - - - "l(2)SH0775, l(2)SH2 0775" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029141 P(3)93B P(3)93B http://flybase.org/reports/FBgn0029141 gene - - - P(3)93B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084135 EP1410 EP1410 http://flybase.org/reports/FBgn0084135 gene - - - EP1410 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034500 CG11200 Carbonyl reductase http://flybase.org/reports/FBgn0034500 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - endomembrane system ; GO:0012505 | inferred from direct assay CG11200 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG11200 11-Aug-17 DroID_v2017_08 "Drer\dhrs13a.1, Drer\rdh14b, Drer\si:ch211-107o10.3, Drer\si:dkey-23o4.6, Drer\zgc:112332, Drer\dhrs13l1, Drer\dhrs12, Drer\rdh14a, Drer\dhrsx, Drer\flj13639, Drer\rdh12, Drer\si:dkey-94e7.2, Drer\cbr1, Drer\si:ch211-165b10.3, Drer\rdh12l, Drer\dhrs13a.3, Drer\si:dkey-174n20.1, Drer\dhrs13a.2, Drer\ascc1, Drer\zgc:153441, Drer\cbr1l, Drer\si:dkey-73n8.3, Drer\zgc:64106" "Scer\YKL107W, Scer\GPI11, Scer\ENV9, Scer\YNL181W" "Cele\C27D8.4, Cele\dhs-17, Cele\dhs-1" "Xtro\dhrsx, Xtro\dhrs13, Xtro\rdh13, Xtro\dhrs12, Xtro\rdh11, Xtro\rdh14, Xtro\ascc1" "Mmus\Dhrsx, Mmus\Cbr3, Mmus\Rdh11, Mmus\Rdh13, Mmus\Cbr1, Mmus\Rdh12, Mmus\Dhrs13, Mmus\1700003E16Rik, Mmus\Wwox, Mmus\Rdh14, Mmus\Ascc1" "Hsap\CBR1, Hsap\DHRS13, Hsap\DHRSX, Hsap\RDH14, Hsap\DHRS12, Hsap\OSTC, Hsap\RDH12, Hsap\C2orf81, Hsap\RDH13, Hsap\RDH11, Hsap\CBR3" viable FBgn0000760 fs(1)A475 female sterile (1) A475 http://flybase.org/reports/FBgn0000760 - gene - - - fs(1)A475 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,heat sensitive,lethal,rescuable maternal effect" FBgn0030877 Arp8 Actin-related protein 8 http://flybase.org/reports/FBgn0030877 protein_coding_gene ATP-dependent 3'-5' DNA helicase activity ; GO:0043140 | contributes_to inferred from sequence or structural similarity with SGD:S000005667 "chromatin remodeling ; GO:0006338 | inferred from sequence or structural similarity with SGD:S000005667 regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay Ino80 complex ; GO:0031011 | inferred from direct assay "Arp8, CG7846, dArp8, arp8" "IPR004000:Actin family, IPR027668:Actin-related protein 8/Plant actin-related protein 9" CG7846 11-Aug-17 DroID_v2017_08 Drer\actr8 Scer\ARP8 - Xtro\actr8 Mmus\Actr8 Hsap\ACTR8 FBgn0023107 anon-13Fa anon-13Fa http://flybase.org/reports/FBgn0023107 - gene - - - anon-13Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037960 mthl5 methuselah-like 5 http://flybase.org/reports/FBgn0037960 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 heart morphogenesis ; GO:0003007 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "Mth-5, anon-WO0170980.71, anon-WO0170980.70, CG6965, mthl5, Mthl5, Gia" "IPR017981:GPCR, family 2-like, IPR000832:GPCR, family 2, secretin-like, IPR023311:Methuselah ectodomain, domain 2" CG6965 11-Aug-17 DroID_v2017_08 Drer\adgrf11 - - - - - viable FBgn0015275 Pc::Su(var)205 Pc::Su(var)205 http://flybase.org/reports/FBgn0015275 - engineered_fusion_gene - - - "POLYCOMB/HP1, Pc::Su(var)205" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260955 CG42587 - http://flybase.org/reports/FBgn0260955 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42587 - CG42587 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265268 CG18234 - http://flybase.org/reports/FBgn0265268 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 molecular_function ; GO:0003674 | no biological data available" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 biological_process ; GO:0008150 | no biological data available" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 cellular_component ; GO:0005575 | no biological data available "CG18234, anon-SAGE:Wang-055" "IPR011990:Tetratricopeptide-like helical domain, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG18234 11-Aug-17 DroID_v2017_08 "Drer\p4ha1b, Drer\p4ha3, Drer\p4ha1a, Drer\p4htm, Drer\zgc:152670, Drer\zgc:158254, Drer\p4ha2" - "Cele\phy-4, Cele\C14E2.4, Cele\Y43F8B.19, Cele\phy-2, Cele\phy-3" "Xtro\p4ha2, Xtro\p4ha1, Xtro\p4ha3" "Mmus\P4htm, Mmus\P4ha1, Mmus\P4ha2, Mmus\P4ha3" "Hsap\P4HA3, Hsap\P4HA2, Hsap\P4HTM, Hsap\P4HA1" FBgn0036160 CG12289 - http://flybase.org/reports/FBgn0036160 protein_coding_gene ketohexokinase activity ; GO:0004454 | inferred from sequence or structural similarity with HGNC:6315 fructokinase activity ; GO:0008865 | inferred from sequence or structural similarity with HGNC:6315 fructose metabolic process ; GO:0006000 | inferred from electronic annotation with InterPro:IPR034093 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:6315 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6315 "BcDNA:AT04143, CG12289" "IPR011611:Carbohydrate kinase PfkB, IPR034093:Ketohexokinase, IPR029056:Ribokinase-like" CG12289 11-Aug-17 DroID_v2017_08 Drer\khk Scer\RBK1 - Xtro\khk Mmus\Khk Hsap\KHK viable FBgn0005365 UB597 UB597 http://flybase.org/reports/FBgn0005365 - gene - - - UB597 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye FBgn0001714 l(1)ESHS35 lethal (1) ESHS35 http://flybase.org/reports/FBgn0001714 - gene - - - l(1)ESHS35 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267121 CR45561 - http://flybase.org/reports/FBgn0267121 non_protein_coding_gene - - - CR45561 - CR45561 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034240 MESR4 Misexpression suppressor of ras 4 http://flybase.org/reports/FBgn0034240 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 germarium-derived oocyte differentiation ; GO:0030706 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr cellular lipid metabolic process ; GO:0044255 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok regulation of gene expression ; GO:0010468 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "MESR4, CG4903, EP0386, EP(2)0988, EP0988, EP988, Mesr4, MSR4" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR028651:ING family, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG4903 11-Aug-17 DroID_v2017_08 "Drer\taf3, Drer\ing3, Drer\ing1, Drer\LOC568955, Drer\ing5a, Drer\ing2, Drer\ing5b, Drer\gtf3aa, Drer\ing4" "Scer\YNG1, Scer\YNG2, Scer\PHO23, Scer\PZF1" "Cele\F21A9.2, Cele\pqm-1, Cele\F10B5.3" "Xtro\ing5, Xtro\ing3, Xtro\ing1, Xtro\taf3, Xtro\ing2" "Mmus\Ing1, Mmus\Ing4, Mmus\Ing3, Mmus\Ing5, Mmus\Ing2, Mmus\Gtf3a, Mmus\Taf3" "Hsap\ING3, Hsap\GTF3A, Hsap\TAF3, Hsap\ING5, Hsap\ING4, Hsap\ING2, Hsap\ING1" "lethal,visible,mitotic cell cycle defective,viable,partially lethal - majority die" "adult abdomen & macrochaeta-537.4,tormogen cell,trichogen cell,ectopic,thecogen cell,dorsocentral bristle,scutellar bristle,wing" FBgn0010886 l(3)06404 lethal (3) 06404 http://flybase.org/reports/FBgn0010886 - gene - - - l(3)06404 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000670 fliD flightless D http://flybase.org/reports/FBgn0000670 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fliD - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,heat sensitive" FBgn0015493 l(3)65ACc lethal (3) 65ACc http://flybase.org/reports/FBgn0015493 - gene - - - "III, l(3)65ACc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052225 CG32225 - http://flybase.org/reports/FBgn0052225 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002000 CG32225 IPR002000:Lysosome-associated membrane glycoprotein CG32225 11-Aug-17 DroID_v2017_08 "Drer\lamp1, Drer\si:ch211-212k18.7, Drer\lamp2, Drer\zgc:165600" - "Cele\lmp-2, Cele\lmp-1" Xtro\lamp5 "Mmus\Lamp5, Mmus\Cd68, Mmus\Lamp2, Mmus\Lamp3, Mmus\Lamp1" "Hsap\CD68, Hsap\LAMP2, Hsap\LAMP3, Hsap\LAMP1, Hsap\LAMP5" viable FBgn0032087 CG9568 - http://flybase.org/reports/FBgn0032087 protein_coding_gene - - - "CG9568, anon-WO0140519.183, FBgn 32087" - CG9568 11-Aug-17 DroID_v2017_08 - - Cele\Y75B12B.13 - - - viable FBgn0013250 E(var)3-4 E(var)3-4 http://flybase.org/reports/FBgn0013250 - gene - - - "E-var(3)4, E(var)3-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant,suppressor of variegation" FBgn0000359 Cp36 Chorion protein 36 http://flybase.org/reports/FBgn0000359 FBgn0000428 protein_coding_gene structural constituent of chorion ; GO:0005213 | non-traceable author statement structural constituent of chorion ; GO:0005213 | inferred from mutant phenotype vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype eggshell chorion assembly ; GO:0007306 | traceable author statement - "Cp36, CG1478, s36, dec2, Dms36, S36, cp36, s365, s36-1, E4, fs(1)C2, dec[[2]], dec-2, CP36" IPR008449:Chorion S36/S38 CG1478 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage | stage S10-14 , adult stage && oogenesis stage | >=stage S10B " follicle cell

adult stage | female " ovary

{ v mus101K451 } , ovary

{ v fs(1)A1059K1 } , ovary

, ovary

{ 0 swa6 } " "female sterile,viable" "chorion,dorsal appendage,egg,maternal effect,chorion | maternal effect,endochorion,vitelline membrane" FBgn0264950 CR44119 - http://flybase.org/reports/FBgn0264950 non_protein_coding_gene - - - CR44119 - CR44119 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260812 inaF-D inaF-D http://flybase.org/reports/FBgn0260812 protein_coding_gene channel regulator activity ; GO:0016247 | inferred from sequence or structural similarity with inaF-B calcium channel regulator activity ; GO:0005246 | inferred from mutant phenotype inferred from genetic interaction with trp regulation of membrane potential ; GO:0042391 | inferred from sequence or structural similarity with inaF-B maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling ; GO:0016058 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from sequence or structural similarity with inaF-B "inaF, inaF-D, CG2457, anon-WO0172774.148, InaF, INAF, CG42563" "IPR029162:TRP-interacting helix, InaF motif" CG42563 11-Aug-17 DroID_v2017_08 Drer\zgc:153157 - Cele\F32D8.15 - Mmus\Inafm1 "Hsap\INAFM1, Hsap\INAFM2" adult stage " eye

, head

" FBgn0011197 l(1)304-60 lethal (1) 304-60 http://flybase.org/reports/FBgn0011197 FBgn0010203 gene - - - "304-60, l(1)304-60" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032385 CG16964 - http://flybase.org/reports/FBgn0032385 protein_coding_gene - - - "BcDNA:GH05159, CG16964" - CG16964 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,planar polarity defective" trichogen cell FBgn0051524 CG31524 - http://flybase.org/reports/FBgn0051524 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 CG31524 "IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013026:Tetratricopeptide repeat-containing domain, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR019734:Tetratricopeptide repeat, IPR011990:Tetratricopeptide-like helical domain" CG31524 11-Aug-17 DroID_v2017_08 "Drer\p4htm, Drer\p4ha1a, Drer\p4ha1b, Drer\zgc:158254, Drer\p4ha3, Drer\zgc:152670, Drer\p4ha2" - "Cele\phy-3, Cele\phy-4, Cele\phy-2, Cele\C14E2.4, Cele\Y43F8B.19" "Xtro\p4ha1, Xtro\p4ha3, Xtro\p4ha2" "Mmus\P4ha2, Mmus\P4ha1, Mmus\P4ha3, Mmus\P4htm" "Hsap\P4HA3, Hsap\P4HA1, Hsap\P4HTM, Hsap\P4HA2" viable FBgn0051407 CG31407 - http://flybase.org/reports/FBgn0051407 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs33d08, NEST:bs35f01, CG31407" IPR031957:Domain of unknown function DUF4777 CG31407 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266896 CR45356 - http://flybase.org/reports/FBgn0266896 non_protein_coding_gene - - - "CR45356, lincRNA.165" - CR45356 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082320 LpR2::Hsap\LRP1 LpR2::Hsap\LRP1 http://flybase.org/reports/FBgn0082320 engineered_fusion_gene - - - LpR2::Hsap\LRP1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036579 CG5027 - http://flybase.org/reports/FBgn0036579 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017937 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607" endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "LD24073p, CG5027" "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site" CG5027 11-Aug-17 DroID_v2017_08 "Drer\tmx1, Drer\tmx3, Drer\tmx4, Drer\zgc:152808" "Scer\EUG1, Scer\PDI1, Scer\EPS1" Cele\ZK973.11 Xtro\tmx3 "Mmus\Tmx4, Mmus\Tmx1, Mmus\Tmx3" "Hsap\TMX1, Hsap\TMX3, Hsap\TMX4" "viable,male semi-sterile,female semi-sterile,fertile" FBgn0028366 l(1)G0006 lethal (1) G0006 http://flybase.org/reports/FBgn0028366 gene - - - l(1)G0006 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,male sterile" FBgn0065849 l(2)SH0309 lethal (2) SH0309 http://flybase.org/reports/FBgn0065849 gene - - - "l(2)SH0309, l(2)SH2 0309" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038405 CG8927 - http://flybase.org/reports/FBgn0038405 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 - - CG8927 IPR000618:Insect cuticle protein CG8927 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026391 Or33b Odorant receptor 33b http://flybase.org/reports/FBgn0026391 - protein_coding_gene "olfactory receptor activity ; GO:0004984 | non-traceable author statement inferred by curator from GO:0004888,GO:0007608 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model olfactory receptor activity ; GO:0004984 | inferred from direct assay olfactory receptor activity ; GO:0004984 | non-traceable author statement" sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay sensory perception of smell ; GO:0007608 | inferred from expression pattern integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "33b, DOR72, CG16961, AN1, 33B.2, dor72, DOR33B.2, Or72, Or33B.2, Or33b" "IPR004117:Olfactory receptor, insect" CG16961 11-Aug-17 DroID_v2017_08 - - - - - - sensory neuron &&of antennal segment 3

"smell perception defective,viable" FBgn0003553 Su(crc) Suppressor of cryptocephal http://flybase.org/reports/FBgn0003553 - gene - - - "Su(crc)1, Su(crc)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003894 Tul Turneduplike http://flybase.org/reports/FBgn0003894 - gene - - - Tul - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263460 snoRNA:CG31191-a - http://flybase.org/reports/FBgn0263460 snoRNA_gene - - - "snoRNA:CG31191-a, snoHACA_06" - CR43575 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267570 CR45910 - http://flybase.org/reports/FBgn0267570 non_protein_coding_gene - - - "CR45910, pri-mir-1000" - CR45910 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032587 CG5953 - http://flybase.org/reports/FBgn0032587 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG5953 "IPR006578:MADF domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG5953 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal,partially lethal - majority die,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0000356 Cp16 Chorion protein 16 http://flybase.org/reports/FBgn0000356 - protein_coding_gene - multicellular organism development ; GO:0007275 | inferred from electronic annotation with InterPro:IPR008450 dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype chorion ; GO:0042600 | inferred from electronic annotation with InterPro:IPR008450 "Cp16, s16, X16715, CP16, Dms16, cp16, s16-1, S16, CG6533, Ov31, melcp16" IPR008450:Chorion S16 CG6533 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage | stage S11-14 , adult stage | female , adult stage && oogenesis stage | stage S13-14 " follicle cell

adult stage | female " ovary

, ovary

{ v mus101K451 } , ovary

{ 0 swa6 } , ovary

{ v fs(1)A1059K1 } " viable dorsal appendage DRSC25549 K -0.069607707 -0.21796029 -0.037792742 0.134395584 2.559367076 0.952596382 FBgn0051971 tRNA:Asp-GTC-2-1 transfer RNA:Aspartic acid-GTC 2-1 http://flybase.org/reports/FBgn0051971 tRNA_gene - - - "tRNA:asp2:25D, tRNA:D2:25D, CR31971, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna8-AspGTC, tRNA:Asp-GTC-2-1, tRNA:CR31971, tRNA-Asp-GTC-2-1, GAC" - CR31971 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014959 fod friend of diaphanous http://flybase.org/reports/FBgn0014959 - gene - - - fod - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage | male , adult stage | female , spermatogenesis && adult stage " male germline stem cell

FBgn0026865 Helena\RTase Helena element reverse transcriptase http://flybase.org/reports/FBgn0026865 - transposable_element_gene - - - Helena\RTase - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040794 CG13056 - http://flybase.org/reports/FBgn0040794 protein_coding_gene - - - CG13056 IPR007614:Retinin-like protein CG13056 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039718 CG15517 - http://flybase.org/reports/FBgn0039718 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15517 IPR031941:Domain of unknown function DUF4773 CG15517 11-Aug-17 DroID_v2017_08 - - Cele\C09D4.2 - - - "viable,visible,body color defective" mesothoracic tergum FBgn0026602 Ady43A Ady43A http://flybase.org/reports/FBgn0026602 FBgn0033152 protein_coding_gene adenosine kinase activity ; GO:0004001 | inferred from biological aspect of ancestor with PANTHER:PTN000062161 adenosine salvage ; GO:0006169 | inferred from biological aspect of ancestor with PANTHER:PTN000062161 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000062161 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000062161 "Ady, Adk43A, CG1851, Ady43A, ady43A, DmAdk3" "IPR002173:Carbohydrate/puine kinase, PfkB, conserved site, IPR011611:Carbohydrate kinase PfkB, IPR029056:Ribokinase-like" CG1851 11-Aug-17 DroID_v2017_08 "Drer\adkb, Drer\adka" Scer\ADO1 Cele\R07H5.8 Xtro\adk Mmus\Adk Hsap\ADK "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC05917 E -0.131282107 0.108905316 3.485213347 0.014319792 0.663603673 0.672466372 FBgn0032189 Ripalpha RPA-interacting protein alpha http://flybase.org/reports/FBgn0032189 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - "CG18145, Ripalpha, dRIPalpha, Tes83" "IPR028156:RPA-interacting protein, IPR028159:RPA-interacting protein, C-terminal domain" CG18145 11-Aug-17 DroID_v2017_08 Drer\rpain - - Xtro\rpain Mmus\Rpain Hsap\RPAIN FBgn0011624 l(2)T56i24 lethal (2) T56i24 http://flybase.org/reports/FBgn0011624 FBgn0005177 gene - - - l(2)T56i24 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0045443 mthl11 methuselah-like 11 http://flybase.org/reports/FBgn0045443 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "CG31147, mthl11" "IPR017981:GPCR, family 2-like, IPR010596:Methuselah, N-terminal domain, IPR023311:Methuselah ectodomain, domain 2, IPR000276:G protein-coupled receptor, rhodopsin-like" CG31147 11-Aug-17 DroID_v2017_08 "Drer\adgrf11, Drer\adgrg6" - Cele\lat-2 Xtro\gpr157 Mmus\Adgre1 "Hsap\ADGRG7, Hsap\ADGRL2" viable FBgn0011974 tRNA:Ser-AGA-1-1 transfer RNA:Serine-AGA 1-1 http://flybase.org/reports/FBgn0011974 "FBgn0003826, FBgn0011968, FBgn0052615, FBgn0060071" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "474, Ser-tRNA-4-7, AE002593.trna8-SerAGA, tRNA:S:AGA:AE002593-a, CR32615, tRNA:ser, tRNA:S, tRNA:ser474:12Eh, tRNA[[Ser]], chrX.trna12-SerAGA, tRNA-Ser-AGA-1-1, tRNA:Ser-AGA-1-1, tRNA:S474:12Eh, UCU" - CR32615 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002386 l(3)93Db lethal (3) 93Db http://flybase.org/reports/FBgn0002386 - gene - - - "er8, l(3)er8, l(3)93Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262380 mir-309 mir-309 stem loop http://flybase.org/reports/FBgn0262380 miRNA_gene - - - "miR-309, mir-309, MIR-309, CR42903, CR33613, dme-mir-309" - CR42903 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011881 tRNA:Ile-AAT-1-3 transfer RNA:Isoleucine-AAT 1-3 http://flybase.org/reports/FBgn0011881 "FBgn0003788, FBgn0052839, FBgn0052842, FBgn0060201" tRNA_gene AUU codon-amino acid adaptor activity ; GO:0033433 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033433 cytosol ; GO:0005829 | inferred by curator from GO:0033433 "CR32842, ile-a, AE002787.trna18-IleAAT, tRNA:I:AAT:AE002787-a, tRNA:ile:49Fa, CR32839, tRNA[Ile], chr2R.trna77-IleAAT, tRNA-Ile[AAU], tRNA-Ile-AAT-1-3, tRNA:Ile-AAT-1-3, tRNA:I:49Fa, AUU" - CR32842 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039920 CG11360 - http://flybase.org/reports/FBgn0039920 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:25297 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0000381 "cg11360, CG11360" "IPR001841:Zinc finger, RING-type, IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11360 11-Aug-17 DroID_v2017_08 "Drer\LOC100534722, Drer\mex3c, Drer\mex3a, Drer\mex3b" - Cele\mex-3 "Xtro\mex3d, Xtro\mex3b, Xtro\mex3c, Xtro\mex3a" "Mmus\Mex3b, Mmus\Mex3c, Mmus\Mex3d, Mmus\Mex3a" "Hsap\MEX3B, Hsap\MEX3A, Hsap\MEX3D, Hsap\MEX3C" viable DRSC17134 K -0.333672061 1.108008442 0.543618397 -0.192115487 0.416747053 -1.69475814 FBgn0031101 CG1631 - http://flybase.org/reports/FBgn0031101 protein_coding_gene - - - CG1631 - CG1631 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000679 flrdB flight reduced B http://flybase.org/reports/FBgn0000679 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdB - - 11-Aug-17 DroID_v2017_08 - - - - - - "jumping defective,flight defective" FBgn0012004 tRNA:Val-CAC-2-6 transfer RNA:Valine-CAC 2-6 http://flybase.org/reports/FBgn0012004 "FBgn0003855, FBgn0011997, FBgn0012005, FBgn0012006, FBgn0051430, FBgn0060021" tRNA_gene GUG codon-amino acid adaptor activity ; GO:0033452 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033452 cytosol ; GO:0005829 | inferred by curator from GO:0033452 "valine tRNA, tRNA[Val][[3b]], AE002708.trna20-ValCAC, tRNA:val3b:92Bd, tRNA:val3b:92Bc, tRNA:val3b:92Bb, tRNA:V:CAC:AE002708-b, tRNA:V3b:92Bd, tRNA:V3b:92Bc, tRNA:V3b, CR31430, chr3R.trna26-ValCAC, tRNA:Val-CAC-2-6, tRNA:V3b:92Bb, tRNA-Val-CAC-2-6, GUG" - CR31430 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014046 Su(tor)2-187-3 Su(tor)2-187-3 http://flybase.org/reports/FBgn0014046 - gene - - - Su(tor)2-187-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033315 beta3GalTII Galactosyltransferase II http://flybase.org/reports/FBgn0033315 protein_coding_gene galactosyltransferase activity ; GO:0008378 | inferred from direct assay galactosyltransferase activity ; GO:0008378 | non-traceable author statement protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR002659 heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from mutant phenotype inferred from genetic interaction with oxt inferred from genetic interaction with Papss inferred from genetic interaction with Ext2 inferred from genetic interaction with Hs3st-B inferred from genetic interaction with Hs6st inferred from genetic interaction with ttv chondroitin sulfate biosynthetic process ; GO:0030206 | non-traceable author statement heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from genetic interaction with β4GalT7 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "CG8734, dbeta3GalTII, GalTII, beta3GalTII, dGAGbeta3GalTII" "IPR002659:Glycosyl transferase, family 31" CG8734 11-Aug-17 DroID_v2017_08 "Drer\b3galt6, Drer\b3galnt2" - "Cele\sqv-2, Cele\T15D6.5, Cele\F14B6.4" "Xtro\b3galt6, Xtro\b3galnt2" "Mmus\B3galt6, Mmus\B3galnt2" "Hsap\B3GALT6, Hsap\B3GALNT2" "visible,viable" "wing,eye,interommatidial bristle" FBgn0040043 CG17643 - http://flybase.org/reports/FBgn0040043 protein_coding_gene - - - CG17643 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005464 l(1)ts79 lethal (1) ts79 http://flybase.org/reports/FBgn0005464 - gene - - - l(1)ts79 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0061023 l(3)S025240 lethal (3) S025240 http://flybase.org/reports/FBgn0061023 gene - - - "0252/40, l(3)S025240" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031531 CG8840 - http://flybase.org/reports/FBgn0031531 protein_coding_gene - - - CG8840 - CG8840 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029573 CG14770 - http://flybase.org/reports/FBgn0029573 protein_coding_gene - - - CG14770 - CG14770 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262731 CG33941 - http://flybase.org/reports/FBgn0262731 protein_coding_gene - - - "pncr013:4, CR33941, CT32596, CG13303, BcDNA:GM01028, MRE3, CG33941" - CG33941 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038692 CG3773 - http://flybase.org/reports/FBgn0038692 protein_coding_gene - - "DNA-directed RNA polymerase II, holoenzyme ; GO:0016591 | inferred from electronic annotation with InterPro:IPR026213" "anon-EST:fe2D12, anon-EST:fe2D10, CG3773" IPR026213:DNA-directed RNA polymerase II subunit GRINL1 CG3773 11-Aug-17 DroID_v2017_08 Drer\polr2m - - - Mmus\Polr2m "Hsap\GCOM1, Hsap\POLR2M" lethal FBgn0060629 l(3)S086102b lethal (3) S086102b http://flybase.org/reports/FBgn0060629 gene - - - "0861/02, l(3)S086102b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019877 anon-69Af anon-69Af http://flybase.org/reports/FBgn0019877 - gene - - - anon-69Af - - 11-Aug-17 DroID_v2017_08 - - - - - - larval stage--adult stage FBgn0014199 l(1)16Ff lethal (1) 16Ff http://flybase.org/reports/FBgn0014199 - gene - - - l(1)16Ff - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "oogonial cell,germline clone,macrochaeta,wing vein" FBgn0010176 tu(1)R tu(1)R http://flybase.org/reports/FBgn0010176 - gene - - - "tu-R, tu(1)R" - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die macrochaeta FBgn0001070 Fs(3)Ven Female sterile (3) Vencellin http://flybase.org/reports/FBgn0001070 - gene molecular_function ; GO:0003674 | no biological data available dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Fs(3)Vencellin, Fs(3)Sz31, Fs(3)Ven" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg,dorsal appendage" FBgn0044476 EP1321 EP1321 http://flybase.org/reports/FBgn0044476 gene - - - EP1321 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0003865 tsg twisted gastrulation http://flybase.org/reports/FBgn0003865 FBgn0001519 protein_coding_gene heparin binding ; GO:0008201 | inferred from direct assay "regulation of transforming growth factor beta receptor signaling pathway ; GO:0017015 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | traceable author statement terminal region determination ; GO:0007362 | inferred from genetic interaction with tor negative regulation of gene expression ; GO:0010629 | inferred from direct assay regulation of BMP signaling pathway ; GO:0030510 | non-traceable author statement" extracellular region ; GO:0005576 | traceable author statement extracellular region ; GO:0005576 | inferred from direct assay "dTsg, l(1)tsg, RF32, l(1)11Ac, l(1)RF32, l(1)11Ab, CG1502, tsg, Tsg" IPR006761:Twisted gastrulation (Tsg) protein CG1502 11-Aug-17 DroID_v2017_08 "Drer\twsg1b, Drer\twsg1a" - Cele\fbxa-74 "Xtro\twsg1, Xtro\twsg2" Mmus\Twsg1 Hsap\TWSG1 " embryonic stage | stage 4,5 , embryonic stage | stage 7 , embryonic stage | 1.5-3 hr , embryonic stage | stage 4-5 , embryonic stage | early " " parasegment 4--10 | dorsal

, posterior transverse furrow

, organism | 90-100% egg length

" "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,viable,lethal,wild-type,visible" "mitotic domain 1,mitotic domain 5,mitotic domain 6,salivary gland,embryo,amnioserosa,wing,wing vein,ectopic" FBgn0020279 lig lingerer http://flybase.org/reports/FBgn0020279 FBgn0033253 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with rin "male mating behavior ; GO:0060179 | inferred from mutant phenotype negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from mutant phenotype negative regulation of imaginal disc growth ; GO:0045571 | inferred from mutant phenotype inferred from genetic interaction with rin inferred from genetic interaction with Fmr1 inferred from genetic interaction with Capr dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from genetic interaction with orb positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype copulation ; GO:0007620 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001046274 cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay "CG8715, lig" "IPR022166:Protein of unknown function DUF3697, ubiquitin-associated protein 2, IPR009060:UBA-like" CG8715 11-Aug-17 DroID_v2017_08 "Drer\ubap2a, Drer\ubap2l, Drer\ubap2b" - Cele\pqn-59 "Xtro\ubap2l, Xtro\ubap2" "Mmus\Ubap2, Mmus\Ubap2l" "Hsap\UBAP2L, Hsap\UBAP2" "viable,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,recessive,mating defective,male,locomotor behavior defective,lethal - all die during pupal stage,male fertile,female fertile,reduced,lethal,size defective,somatic clone,nutrition conditional,increased cell death" "wing disc,eye,somatic clone,ommatidium,supernumerary,wing,nutrition conditional" DRSC07247 I -0.320694351 -2.586310091 -0.912449 1.146442677 -0.315473804 -0.87806481 FBgn0053356 5SrRNA-Psi:CR33356 5SrRNA-Psi:CR33356 http://flybase.org/reports/FBgn0053356 pseudogene_attribute - - - "CR33356, 5SrRNA-Psi:CR33356" - CR33356 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000130 Ars-region8 Autonomous replicating sequence region 8 http://flybase.org/reports/FBgn0000130 - region - - - "ars413, Ars-region8, Ars8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050338 CG30338 - http://flybase.org/reports/FBgn0050338 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30338 "IPR006575:RWD domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR017359:Uncharacterised conserved protein UCP038021, RWD, IPR010541:Domain of unknown function DUF1115" CG30338 11-Aug-17 DroID_v2017_08 Drer\rwdd2b - - "Xtro\rwdd2b, Xtro\rwdd2a, Xtro\rwdd3" "Mmus\Rwdd2b, Mmus\Rwdd2a, Mmus\Rwdd3" "Hsap\RWDD3, Hsap\RWDD2B, Hsap\RWDD2A" viable FBgn0003730 ton tonochaetae http://flybase.org/reports/FBgn0003730 - gene - - - ton - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,viable,male,reduced" "macrochaeta,eye,ommatidium,wing,wing vein,crossvein" FBgn0015422 l(1)17Da lethal (1) 17Da http://flybase.org/reports/FBgn0015422 - gene - - - l(1)17Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019644 ATPsynB "ATP synthase, subunit B" http://flybase.org/reports/FBgn0019644 - protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000296496 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000005999" ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000005999 phagocytosis ; GO:0006909 | inferred from mutant phenotype ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000296496 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P24539 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with UniProtKB:P24539 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from biological aspect of ancestor with PANTHER:PTN000296496 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay" "CG8189, ATPsyn-b, ATP syn-b, ATPF, ATPsynB, ATP-syn-B" "IPR008688:ATP synthase, F0 complex, subunit B/MI25, IPR013837:ATP synthase, F0 complex, subunit B" CG8189 11-Aug-17 DroID_v2017_08 Drer\atp5f1 Scer\ATP4 "Cele\asb-2, Cele\asb-1" Xtro\atp5f1 Mmus\Atp5f1 Hsap\ATP5F1 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC09659 E -1.159347393 -0.09285039 -0.192487128 -3.083890496 0.061939286 0.481505071 FBgn0259312 C762 - http://flybase.org/reports/FBgn0259312 gene - - - C762 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0010785 l(3)02634 lethal (3) 02634 http://flybase.org/reports/FBgn0010785 - gene - - - l(3)02634 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067086 JK1469 JK1469 http://flybase.org/reports/FBgn0067086 gene - - - JK1469 - - 11-Aug-17 DroID_v2017_08 - - - - - - neurophysiology defective FBgn0024667 l(2)k05001 lethal (2) k05001 http://flybase.org/reports/FBgn0024667 - gene - - - "50/1, l(2)k05001" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0040890 ksh kish http://flybase.org/reports/FBgn0040890 protein_coding_gene - protein secretion ; GO:0009306 | inferred from mutant phenotype intracellular transport ; GO:0046907 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "ksh, CG14199" IPR009653:Protein kish CG14199 11-Aug-17 DroID_v2017_08 "Drer\tmem167a, Drer\tmem167b" Scer\KSH1 Cele\K07F5.15 "Xtro\tmem167a, Xtro\tmem167b" "Mmus\Tmem167b, Mmus\Tmem167" "Hsap\TMEM167B, Hsap\TMEM167A" lethal FBgn0031791 AANATL2 Arylalkylamine N-acyltransferase-like 2 http://flybase.org/reports/FBgn0031791 protein_coding_gene acyl-CoA N-acyltransferase activity ; GO:0019186 | inferred from direct assay aralkylamine N-acetyltransferase activity ; GO:0004059 | inferred from direct assay nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 "CG9486, AANATL2" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG9486 11-Aug-17 DroID_v2017_08 - - "Cele\anat-1, Cele\T10B5.4, Cele\R05H10.7, Cele\R05H10.1, Cele\W02D7.4, Cele\M7.8, Cele\W02D7.5, Cele\M7.12" - - - viable FBgn0065183 l(3)A143.1F3 lethal (3) A143.1F3 http://flybase.org/reports/FBgn0065183 gene - - - l(3)A143.1F3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,recessive" FBgn0015006 Abl::Hsap\ABL1 ABL1 http://flybase.org/reports/FBgn0015006 - engineered_fusion_gene - - - Abl::Hsap\ABL1 - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type FBgn0266653 CR45160 - http://flybase.org/reports/FBgn0266653 non_protein_coding_gene - - - CR45160 - CR45160 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051005 qless qless http://flybase.org/reports/FBgn0051005 protein_coding_gene - response to mitochondrial depolarisation ; GO:0098780 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype isoprenoid biosynthetic process ; GO:0008299 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype - "CG3684, CG15565, anon-WO0118547.422, qless, CG31005" "IPR000092:Polyprenyl synthetase, IPR008949:Isoprenoid synthase domain, IPR033749:Polyprenyl synthetase, conserved site" CG31005 11-Aug-17 DroID_v2017_08 "Drer\pdss2, Drer\pdss1" Scer\COQ1 Cele\coq-1 "Xtro\pdss1, Xtro\pdss2" "Mmus\Pdss2, Mmus\Pdss1" "Hsap\PDSS2, Hsap\PDSS1" "neuroanatomy defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell death,stress response defective,hyperactive,dominant,uncoordinated,flightless" "embryonic/larval neuroblast,somatic clone" DRSC15103 E 0.445433751 -0.338554017 -1.591838408 -0.096138518 0.203029373 0.489316527 FBgn0028964 AER-d AER-d http://flybase.org/reports/FBgn0028964 region - - - AER-d - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016666 Hrp54 Hrp54 http://flybase.org/reports/FBgn0016666 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "hrp54, Hrp54" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015890 anon-75Cd anon-75Cd http://flybase.org/reports/FBgn0015890 - gene - - - anon-75Cd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014887 Su(phl)6 Suppressor of pole hole 6 http://flybase.org/reports/FBgn0014887 - gene - - - "Su(D-raf)6, Su(phl)6" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262813 CG43184 - http://flybase.org/reports/FBgn0262813 protein_coding_gene - - - "CG43184, chr3L_13830834_13831226.0" - CG43184 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066098 MCP-4.s MCP-4.s http://flybase.org/reports/FBgn0066098 gene - - - "MCP-4 s, MCP-4.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044873 E(Mer)IIb E(Mer)IIb http://flybase.org/reports/FBgn0044873 gene - - - "IIb, E(Mer)IIb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,visible" "wing vein,ectopic" FBgn0002890 mus204 mutagen-sensitive 204 http://flybase.org/reports/FBgn0002890 - gene - - - mus204 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female fertile,reduced,meiotic cell cycle defective,DNA repair defective,chemical sensitive,recessive,radiation sensitive" FBgn0082932 snoRNA:Me28S-G1083d snoRNA:Me28S-G1083d http://flybase.org/reports/FBgn0082932 snoRNA_gene rRNA 2'-O-ribose methylation guide activity ; GO:0030562 | inferred from sequence model rRNA 2'-O-methylation ; GO:0000451 | inferred from sequence model nucleolus ; GO:0005730 | inferred from direct assay "snoRNA:Me28S-G1083d, Me28S-Gm1083d, CR34565, DmSnR60, DmSnR60d" - CR34565 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267271 CR45707 - http://flybase.org/reports/FBgn0267271 non_protein_coding_gene - - - CR45707 - CR45707 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040485 BobC Brother of Bearded C http://flybase.org/reports/FBgn0040485 gene protein binding ; GO:0005515 | inferred from physical interaction with neur - - "Bob-C, Bob, BobC" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037647 RagA-B Ras-related GTP binding A/B http://flybase.org/reports/FBgn0037647 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006762 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with RagC-D cellular response to starvation ; GO:0009267 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Gtr1, dRagB, dRagA, CG11968, RagA-B, RagA, Rag, RagA/B, ragA, rag" "IPR006762:Gtr1/RagA G protein, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG11968 11-Aug-17 DroID_v2017_08 Drer\rraga Scer\GTR1 "Cele\raga-1, Cele\F57C12.2" Xtro\rraga "Mmus\Rragb, Mmus\Il4, Mmus\Rraga" "Hsap\RRAGA, Hsap\RRAGB, Hsap\IL4" "increased cell size,stress response defective,size defective,increased cell number,visible,decreased cell size,decreased cell number,viable" "wing,posterior compartment,autophagic vacuoleunspecified" FBgn0267261 CR45697 - http://flybase.org/reports/FBgn0267261 non_protein_coding_gene - - - CR45697 - CR45697 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024649 l(2)k09316 lethal (2) k09316 http://flybase.org/reports/FBgn0024649 - gene - - - "93/16, l(2)k09316" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020660 eIF4B eukaryotic translation initiation factor 4B http://flybase.org/reports/FBgn0020660 "FBgn0040057, FBan0010837" protein_coding_gene RNA strand-exchange activity ; GO:0034057 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 ribosomal small subunit binding ; GO:0043024 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity RNA strand annealing activity ; GO:0033592 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 translation initiation factor activity ; GO:0003743 | inferred from physical interaction with eIF4E1 translational initiation ; GO:0006413 | inferred from sequence or structural similarity translational initiation ; GO:0006413 | inferred from physical interaction with eIF4E1 eukaryotic translation initiation factor 4F complex assembly ; GO:0097010 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 formation of translation preinitiation complex ; GO:0001731 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 cytoplasmic translation ; GO:0002181 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay cytosol ; GO:0005829 | inferred from physical interaction with eIF4E1 polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 "CG10837, Dm-eIF4B, eIF4B, Eif4B, EIF-4B, eIF-4B-L, eIF-4B-S, eIf4b, eIF-4b, eIF4B-S, eIF4B-L, eIF-4B" "IPR000504:RNA recognition motif domain, IPR033107:Eukaryotic translation initiation factor 4B" CG10837 11-Aug-17 DroID_v2017_08 "Drer\eif4h, Drer\eif4ba, Drer\eif4bb" Scer\TIF3 Cele\drr-2 "Xtro\eif4h, Xtro\eif4b" "Mmus\Eif4b, Mmus\Eif4h" "Hsap\EIF4H, Hsap\EIF4B" "viable,cell lethal,conditional,cell growth defective,visible" "eye,ommatidium,chaeta,supernumerary" FBgn0005723 l(1)TK132 lethal (1) TK132 http://flybase.org/reports/FBgn0005723 - gene - - - "l132, l(1)TK132" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" lamina FBgn0022993 ors outer rhabdomeres small http://flybase.org/reports/FBgn0022993 - gene - - - ors - - 11-Aug-17 DroID_v2017_08 - - - - - - rhabdomere FBgn0261403 sxc super sex combs http://flybase.org/reports/FBgn0261403 protein_coding_gene "transferase activity, transferring glycosyl groups ; GO:0016757 | inferred from mutant phenotype acetylglucosaminyltransferase activity ; GO:0008375 | inferred from mutant phenotype" regulation of gene expression ; GO:0010468 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype protein glycosylation ; GO:0006486 | inferred from mutant phenotype protein O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype - "Ogt, sxc, OGT, sxc/Ogt, CG10392, l(2)NC130, SXC, Sxc, BcDNA:GH04245, l(2)02637, P1201, ogt, dO-GnT, DmOGT" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR029489:O-GlcNAc transferase, C-terminal, IPR027363:Methylthioribose-1-phosphate isomerase-like, N-terminal domain, IPR001440:Tetratricopeptide repeat 1" CG10392 11-Aug-17 DroID_v2017_08 "Drer\ttc13, Drer\ogt.1, Drer\ogt.2" - Cele\ogt-1 "Xtro\ttc13, Xtro\ogt" "Mmus\Ogt, Mmus\Ttc13" "Hsap\OGT, Hsap\TTC13" DRSC04911 E -1.095205936 -0.335277595 -1.981941137 0.199378581 0.589845769 -1.203506137 FBgn0024550 l(3)L3930 lethal (3) L3930 http://flybase.org/reports/FBgn0024550 - gene - - - l(3)L3930 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003712 thick thick http://flybase.org/reports/FBgn0003712 - gene - - - "thick, tk" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,leg,wing" FBgn0016729 Rst(2)Lb Resistance to Leptopilina boulardi http://flybase.org/reports/FBgn0016729 - gene - - - "rlb, Rlb, Rst(2)Lb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032218 CG5381 - http://flybase.org/reports/FBgn0032218 protein_coding_gene - - - CG5381 - CG5381 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011696 Pebp2beta Pebp2beta http://flybase.org/reports/FBgn0011696 - gene - - - Pebp2beta - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033842 cbc crowded by cid http://flybase.org/reports/FBgn0033842 protein_coding_gene polynucleotide 5'-hydroxyl-kinase activity ; GO:0051731 | inferred from biological aspect of ancestor with PANTHER:PTN000978836 "tRNA splicing, via endonucleolytic cleavage and ligation ; GO:0006388 | inferred from biological aspect of ancestor with PANTHER:PTN000298076 mRNA cleavage ; GO:0006379 | inferred from biological aspect of ancestor with PANTHER:PTN000298076 mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000298076 tRNA splicing, via endonucleolytic cleavage and ligation ; GO:0006388 | inferred from sequence or structural similarity with UniProtKB:Q92989 neurogenesis ; GO:0022008 | inferred from mutant phenotype" mRNA cleavage factor complex ; GO:0005849 | inferred from electronic annotation with InterPro:IPR028606 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000978836 tRNA-intron endonuclease complex ; GO:0000214 | inferred from sequence or structural similarity with UniProtKB:Q92989 "cg5970, cbc, CG5970" "IPR010655:Pre-mRNA cleavage complex subunit Clp1, IPR028606:Polyribonucleotide 5-hydroxyl-kinase Clp1, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR032324:Clp1, N-terminal beta-sandwich domain, IPR032319:Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain" CG5970 11-Aug-17 DroID_v2017_08 Drer\clp1 "Scer\CLP1, Scer\GRC3" Cele\clpf-1 Xtro\clp1 Mmus\Clp1 Hsap\CLP1 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0263487 scaRNA:PsiU5-44 small Cajal body-specific RNA : PsiU5-44 http://flybase.org/reports/FBgn0263487 snoRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "scaRNA:PsiU5-44, pugU5-44, snoRNA:tra2-a" - CR43602 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026593 CG5707 - http://flybase.org/reports/FBgn0026593 FBgn0035314 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "HL03644, BEST:HL03644, CG5707" "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG5707 11-Aug-17 DroID_v2017_08 Drer\serhl - Cele\W01A11.1 "Xtro\serhl, Xtro\serhl2" Mmus\Serhl Hsap\SERHL2 "viable,fertile" FBgn0065447 l(2)SH1406 lethal (2) SH1406 http://flybase.org/reports/FBgn0065447 gene - - - "l(2)SH1406, l(2)SH2 1406" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024220 ird8 immune response deficient 8 http://flybase.org/reports/FBgn0024220 - gene - positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype - "ird, ird8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,recessive,immune response defective,melanotic mass phenotype" melanotic mass FBgn0039154 Npc2f Niemann-Pick type C-2f http://flybase.org/reports/FBgn0039154 protein_coding_gene sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 intracellular cholesterol transport ; GO:0032367 | inferred from electronic annotation with InterPro:IPR033916 sterol transport ; GO:0015918 | inferred from sequence or structural similarity with Npc2a - "BcDNA:LP08842, CG6164, npc2f, Npc2f" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set, IPR033916:ML domain, Npc2 like" CG6164 11-Aug-17 DroID_v2017_08 "Drer\npc2, Drer\zgc:193725" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 "viable,fertile" FBgn0042104 CG18747 - http://flybase.org/reports/FBgn0042104 protein_coding_gene - - - "CG18747, Q9I7L1_DROME" "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG18747 11-Aug-17 DroID_v2017_08 "Drer\arrdc1b, Drer\arrdc1a, Drer\zgc:110353, Drer\LOC799768, Drer\txnipb, Drer\arrdc3b, Drer\arrdc3a, Drer\si:ch211-130m23.2, Drer\txnipa, Drer\zgc:110626, Drer\arrdc2" "Scer\ALY2, Scer\ROD1, Scer\ALY1, Scer\CSR2, Scer\LDB19, Scer\RIM8, Scer\ECM21, Scer\ART5, Scer\ROG3" "Cele\arrd-23, Cele\arrd-11, Cele\arrd-14, Cele\arrd-3, Cele\arrd-9, Cele\arrd-22, Cele\arrd-16, Cele\arrd-4, Cele\arrd-1, Cele\arrd-7, Cele\arrd-8, Cele\arrd-19, Cele\rnh-1.2, Cele\arrd-2, Cele\arrd-6, Cele\arrd-15, Cele\arrd-13, Cele\arrd-18, Cele\arrd-24, Cele\arrd-12, Cele\arrd-25, Cele\arrd-5, Cele\arrd-27" "Xtro\arrdc4, Xtro\arrdc3, Xtro\txnip, Xtro\arrdc2" "Mmus\Arrdc3, Mmus\Arrdc1, Mmus\Arrdc2, Mmus\Txnip, Mmus\Arrdc4, Mmus\Arrdc5" "Hsap\ARRDC3, Hsap\ARRDC2, Hsap\ARRDC4, Hsap\ARRDC1, Hsap\TXNIP, Hsap\ARRDC5" viable FBgn0010725 l(3)00714 lethal (3) 00714 http://flybase.org/reports/FBgn0010725 - gene - - - l(3)00714 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0020618 Rack1 Receptor of activated protein kinase C 1 http://flybase.org/reports/FBgn0020618 - protein_coding_gene - "muscle cell cellular homeostasis ; GO:0046716 | inferred from genetic interaction with Dg inferred from genetic interaction with Dys wing disc development ; GO:0035220 | inferred from mutant phenotype positive regulation by host of viral genome replication ; GO:0044829 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype IRES-dependent viral translational initiation ; GO:0075522 | inferred from mutant phenotype negative regulation of protein phosphorylation ; GO:0001933 | inferred from mutant phenotype positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from mutant phenotype oviposition ; GO:0018991 | inferred from mutant phenotype regulation of autophagosome size ; GO:0016243 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype positive regulation of glycogen biosynthetic process ; GO:0045725 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay autophagosome ; GO:0005776 | inferred from direct assay "i173, CG7111, RACK1, rack1, Rack1, dRack1" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG7111 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-266o15.4, Drer\gnb2l1" Scer\ASC1 Cele\rack-1 Xtro\gnb2l1 "Mmus\Rack1, Mmus\Wdr31" "Hsap\WDR31, Hsap\RACK1" "sterile,lethal - all die before end of larval stage,some die during larval stage,recessive,viable,visible,lethal,germline clone" "wing,cuticle,ovary,female germline stem cell,egg,trichogen cell,egg chamber,ring canal,germline clone,embryonic/larval fat body,glycogen granule,autophagic vacuole,embryonic/larval fat body | larval stage,autophagic vacuoleFRT.RnorCD2.Act5C,glycogen granuleFRT.RnorCD2.Act5C" DRSC23796 IK 0.401673533 2.122076413 0.301394475 -0.388200723 -0.941632822 2.548208513 FBgn0038407 CG6126 - http://flybase.org/reports/FBgn0038407 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 "CT19169, CG6126" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG6126 11-Aug-17 DroID_v2017_08 "Drer\sv2bb, Drer\slc22a7b.3, Drer\slc22a7b.1, Drer\LOC101884074, Drer\slc22a16, Drer\sv2a, Drer\sv2, Drer\svopa, Drer\zgc:175176, Drer\slc22a7a, Drer\LOC100334012, Drer\oatx, Drer\slc22a6l, Drer\zgc:153639, Drer\slc22a13, Drer\slc22a21, Drer\slc22a5, Drer\zmp:0000001102, Drer\si:dkey-166k12.1, Drer\slc22a7b.2, Drer\sv2c" "Scer\AQR1, Scer\TPO1, Scer\TPO2, Scer\QDR1, Scer\QDR3, Scer\YHK8, Scer\DTR1, Scer\PHO84, Scer\TPO3, Scer\QDR2, Scer\HXT9, Scer\GIT1, Scer\FLR1" "Cele\ZK892.3, Cele\oct-1, Cele\Y82E9BR.16, Cele\F45E10.2, Cele\Y51A2D.18, Cele\Y57G11C.23, Cele\svop-1, Cele\C46C2.2, Cele\Y66D12A.13, Cele\C53B4.1" "Xtro\sv2a, Xtro\svop, Xtro\sv2b, Xtro\slc22a13, Xtro\slc22a5, Xtro\slc22a4, Xtro\slc22a6, Xtro\slc22a16, Xtro\sv2c" "Mmus\Sv2a, Mmus\Slc22a26, Mmus\Slc22a28, Mmus\Slc22a16, Mmus\Slc22a2, Mmus\Slc22a20, Mmus\Slc22a29, Mmus\Slc22a23, Mmus\Sv2b, Mmus\Slc22a7, Mmus\Slc22a30, Mmus\Sv2c, Mmus\Slc22a6, Mmus\Slc22a22, Mmus\Slc22a8, Mmus\Slc22a5, Mmus\Slc22a12, Mmus\Slc22a21, Mmus\Slc22a27, Mmus\Slc22a4, Mmus\Slc22a13, Mmus\Svop, Mmus\Slc22a19, Mmus\Slc22a14" "Hsap\SLC22A12, Hsap\SLC22A23, Hsap\SLC22A24, Hsap\SLC22A2, Hsap\SLC22A13, Hsap\SLC22A9, Hsap\SLC22A11, Hsap\SLC22A4, Hsap\SLC22A7, Hsap\SLC22A8, Hsap\SLC22A5, Hsap\SLC22A16, Hsap\SLC22A1, Hsap\SLC22A20, Hsap\SLC22A25, Hsap\SV2C, Hsap\SV2B, Hsap\SV2A, Hsap\SVOP, Hsap\SLC22A10, Hsap\SLC22A6" "viable,fertile" DRSC15971 K -0.424372815 0.135434695 -0.221225313 0.518501601 1.015269836 1.854469737 FBgn0003434 slw slope wing http://flybase.org/reports/FBgn0003434 - gene - - - slw - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,viable,visible,recessive" wing FBgn0050183 CG30183 - http://flybase.org/reports/FBgn0050183 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity with HGNC:14082 mitotic cytokinesis ; GO:0000281 | inferred from sequence or structural similarity with HGNC:14082 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:14082 actin cytoskeleton ; GO:0015629 | inferred from sequence or structural similarity with HGNC:14082 "CG4530, CG4093, CG30183" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG30183 11-Aug-17 DroID_v2017_08 "Drer\anln, Drer\si:dkey-30c15.10" - "Cele\ani-3, Cele\C03B1.7, Cele\ani-2, Cele\ani-1" - Mmus\Anln Hsap\ANLN viable DRSC04472 K 0.178345619 0.125936328 0.136915914 0.584630082 2.112812131 0.743870314 FBgn0058356 CG40356 - http://flybase.org/reports/FBgn0058356 protein_coding_gene - - - CG40356 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259306 C242 - http://flybase.org/reports/FBgn0259306 gene - - - C242 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta" FBgn0264744 CG44002 - http://flybase.org/reports/FBgn0264744 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 zinc ion binding ; GO:0008270 | inferred from sequence model with InterPro:IPR007087,InterPro:IPR012934,InterPro:IPR015880 DNA binding ; GO:0003677 | inferred from direct assay" biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 nucleus ; GO:0005634 | inferred from sequence model with InterPro:IPR012934 "CG44002, CG34406-2, CG34406, CG18555" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG44002 11-Aug-17 DroID_v2017_08 "Drer\LOC101884037, Drer\zgc:174650, Drer\LOC101882721, Drer\zgc:101130" Scer\ZAP1 - - - "Hsap\ZNF771, Hsap\ZNF501, Hsap\ZNF648" viable FBgn0010660 Nup214 Nucleoporin 214kD http://flybase.org/reports/FBgn0010660 FBgn0034798 protein_coding_gene structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 protein binding ; GO:0005515 | inferred from physical interaction with emb protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9GYU8 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 protein localization to nuclear pore ; GO:0090204 | inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype negative regulation of protein export from nucleus ; GO:0046826 | inferred from mutant phenotype nuclear pore central transport channel ; GO:0044613 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 microtubule associated complex ; GO:0005875 | inferred from direct assay nuclear pore nuclear basket ; GO:0044615 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 nuclear pore ; GO:0005643 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from mutant phenotype "DNup214, CAN/Nup214, dCAN, CG3820, DCAN, l(2)10444, Nup214, CAN, Nup 214, nup214, Nup, NUP214" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR026054:Nuclear pore complex protein" CG3820 11-Aug-17 DroID_v2017_08 Drer\nup214 "Scer\NUP159, Scer\NUP1" Cele\npp-14 Xtro\nup214 Mmus\Nup214 Hsap\NUP214 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,cell growth defective" DRSC04421 K -0.47133738 0.850111723 0.055715324 0.325548257 1.741295498 -0.728281174 FBgn0015697 E(cact[E10])81 "Enhancer of cactus[E10], number 81" http://flybase.org/reports/FBgn0015697 - gene - - - E(cact[E10])81 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036030 CG6767 - http://flybase.org/reports/FBgn0036030 protein_coding_gene "ribose phosphate diphosphokinase activity ; GO:0004749 | inferred from electronic annotation with InterPro:IPR000842, InterPro:IPR005946 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR000842, InterPro:IPR005946" ribonucleoside monophosphate biosynthetic process ; GO:0009156 | inferred from electronic annotation with InterPro:IPR000842 nucleotide biosynthetic process ; GO:0009165 | inferred from electronic annotation with InterPro:IPR005946 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000836 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - CG6767 "IPR000842:Phosphoribosyl pyrophosphate synthetase, conserved site, IPR005946:Ribose-phosphate diphosphokinase, IPR029099:Ribose-phosphate pyrophosphokinase, N-terminal domain, IPR029057:Phosphoribosyltransferase-like, IPR000836:Phosphoribosyltransferase domain" CG6767 11-Aug-17 DroID_v2017_08 "Drer\prps1a, Drer\prps1b, Drer\prpsap2" "Scer\PRS4, Scer\PRS2, Scer\PRS1, Scer\PRS5, Scer\PRS3" "Cele\W04G3.5, Cele\R151.2" "Xtro\prps1, Xtro\prps2, Xtro\prpsap1" "Mmus\Prps1l1, Mmus\Prpsap2, Mmus\Prps1, Mmus\Prpsap1, Mmus\Prps2, Mmus\Prps1l3" "Hsap\PRPSAP2, Hsap\PRPS1, Hsap\PRPS1L1, Hsap\PRPS2, Hsap\PRPSAP1" "viable,visible" trichogen cell DRSC08994 E -0.081210179 -0.074642132 -0.754761928 1.866865352 -0.850509604 0.86300685 FBgn0003352 seg short egg http://flybase.org/reports/FBgn0003352 - gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - "l(1)SE, seg" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible egg FBgn0001435 l(1)7Bc lethal (1) 7Bc http://flybase.org/reports/FBgn0001435 - gene - - - l(1)7Bc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,polyphasic,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011828 Pxn Peroxidasin http://flybase.org/reports/FBgn0011828 - protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 phagocytosis ; GO:0006909 | inferred from mutant phenotype extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000895746 "CG12002, pxn, Dpxn, CT1239, Pxn, DmPxd-a" "IPR000372:Leucine-rich repeat N-terminal domain, IPR001007:VWFC domain, IPR003591:Leucine-rich repeat, typical subtype, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR010255:Haem peroxidase, IPR013783:Immunoglobulin-like fold, IPR019791:Haem peroxidase, animal, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR013098:Immunoglobulin I-set" CG12002 11-Aug-17 DroID_v2017_08 "Drer\ptgs2b, Drer\ptgs2a, Drer\tpo, Drer\pxdn, Drer\epx, Drer\mpx, Drer\igsf9bb, Drer\bgna, Drer\ptgs1" - "Cele\pxn-2, Cele\skpo-1, Cele\skpo-2, Cele\skpo-3, Cele\mlt-7, Cele\pxn-1, Cele\slt-1" "Xtro\epx, Xtro\tpo, Xtro\ptgs1, Xtro\ptgs2, Xtro\mpo, Xtro\fmod, Xtro\pxdn" "Mmus\Ceacam9, Mmus\Ptgs1, Mmus\Prelp, Mmus\Pxdn, Mmus\Epx, Mmus\Lpo, Mmus\Lrrtm3, Mmus\Ptgs2, Mmus\Tpo, Mmus\Dcn, Mmus\Mpo" "Hsap\PXDNL, Hsap\LPO, Hsap\TPO, Hsap\PTGS1, Hsap\PTGS2, Hsap\EPX, Hsap\MPO, Hsap\PXDN" " larval stage , embryonic stage " " gastric caecum

, embryonic/larval fat body

, hemocyte

" embryonic stage " organism

, hemocyte

" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266454 CG45079 - http://flybase.org/reports/FBgn0266454 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45079 - CG45079 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022667 Dep2 Dep2 http://flybase.org/reports/FBgn0022667 - gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "DEP2, Dep2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259854 Su(Ste):CR42423 Su(Ste):CR42423 http://flybase.org/reports/FBgn0259854 non_protein_coding_gene - - - "Su(Ste):CR42423, CR42423" - CR42423 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263743 CG43668 - http://flybase.org/reports/FBgn0263743 protein_coding_gene - - - "CG43668, CG15226" - CG43668 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005752 l(1)TK307 lethal (1) TK307 http://flybase.org/reports/FBgn0005752 - gene - - - "l307, l(1)TK307" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0036707 CG13724 - http://flybase.org/reports/FBgn0036707 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13724 - CG13724 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC10053 E -1.455881331 0.426437307 2.806769261 -0.406840833 1.472298735 1.192553512 FBgn0028525 c(2)M crossover suppressor on 2 of Manheim http://flybase.org/reports/FBgn0028525 protein_coding_gene - meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype resolution of meiotic recombination intermediates ; GO:0000712 | inferred from mutant phenotype cohesin complex ; GO:0008278 | colocalizes_with inferred from direct assay "C(2)M, mei-910, MEI-910, DS02740.10, BG:DS02740.10, CG4249, c(2)M, c(2)m" "IPR006910:Rad21/Rec8-like protein, N-terminal" CG4249 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | female && oogenesis stage | stage S1-7 presumptive oocyte && oocyte

"meiotic cell cycle defective,female fertile,viable,female,germline clone" FBgn0028260 l(3)66Ea lethal (3) 66Ea http://flybase.org/reports/FBgn0028260 gene - - - l(3)66Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260220 KG01932 - http://flybase.org/reports/FBgn0260220 gene - - - KG01932 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "sex comb,sex comb tooth" FBgn0039029 CG4704 - http://flybase.org/reports/FBgn0039029 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - CG4704 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG4704 11-Aug-17 DroID_v2017_08 "Drer\micu3a, Drer\micu3b, Drer\micu1, Drer\micu2" - Cele\micu-1 "Xtro\micu1, Xtro\micu2" "Mmus\Micu1, Mmus\Micu2, Mmus\Micu3" "Hsap\MICU2, Hsap\MICU1, Hsap\MICU3" viable FBgn0085518 CG40794 - http://flybase.org/reports/FBgn0085518 protein_coding_gene - - - CG40794 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250895 zaa36f12 - http://flybase.org/reports/FBgn0250895 gene - - - "zaa36f12, zaa36f12y1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038906 CG13416 - http://flybase.org/reports/FBgn0038906 protein_coding_gene - - - CG13416 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005264 l(3)SG84 lethal (3) SG84 http://flybase.org/reports/FBgn0005264 - gene - - - "l(3)2614, l(3)SG84" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0032269 w-cup world cup http://flybase.org/reports/FBgn0032269 protein_coding_gene - - - "CG7363, BcDNA:AT31112, w-cup" - CG7363 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026738 CG7857 - http://flybase.org/reports/FBgn0026738 - protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:32312 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:32312 cellular_component ; GO:0005575 | no biological data available "anon-Becker1, CG7857, Q9VUN9" IPR003323:OTU domain CG7857 11-Aug-17 DroID_v2017_08 Drer\otud6b Scer\OTU2 Cele\otub-3 Xtro\otud6b "Mmus\Otud6a, Mmus\Otud6b" "Hsap\OTUD6B, Hsap\OTUD6A, Hsap\HOOK2" "viable,fertile" FBgn0085712 CG41588 - http://flybase.org/reports/FBgn0085712 protein_coding_gene - - - CG41588 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045059 fs(1)140 female sterile (1) 140 http://flybase.org/reports/FBgn0045059 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)140 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "nurse cell & actin filament,nurse cell & nucleus" FBgn0014174 fs(?)A253.1M3 fs(?)A253.1M3 http://flybase.org/reports/FBgn0014174 - gene - - - fs(?)A253.1M3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cold sensitive,female sterile" FBgn0031784 CG9222 - http://flybase.org/reports/FBgn0031784 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:30410 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein kinase activity ; GO:0004672 | non-traceable author statement" neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:30410 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 CG9222 "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG9222 11-Aug-17 DroID_v2017_08 Drer\tssk6 "Scer\VHS1, Scer\PRR1, Scer\SKS1, Scer\KSP1, Scer\FRK1, Scer\KIN4" "Cele\Y38H8A.4, Cele\kin-33, Cele\tag-344, Cele\C27D6.11, Cele\W02B12.12, Cele\F23C8.8" - "Mmus\Tssk3, Mmus\Tssk2, Mmus\Tssk1, Mmus\Tssk4, Mmus\Tssk6" "Hsap\TSSK6, Hsap\TSSK3, Hsap\TSSK4, Hsap\TSSK1B, Hsap\TSSK2" viable FBgn0004931 a(1)HM26 abnormal abdomen HM26 http://flybase.org/reports/FBgn0004931 - gene - - - "l(1)HM26, a(1)HM26" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,cold sensitive" "tergite,sternite" FBgn0026351 Su(SuRaf1)IV Su(SuRaf1)IV http://flybase.org/reports/FBgn0026351 - gene - - - "Su[Su(Raf)1]IV, Su(SuRaf1)IV" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260857 Bet1 Blocked early in transport 1 http://flybase.org/reports/FBgn0260857 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity syntaxin binding ; GO:0019905 | inferred from sequence or structural similarity with RGD:2203 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with RGD:2203 neurogenesis ; GO:0022008 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with RGD:2203 "G14084, BET1, bs16e01.y1, BcDNA:RH40423, CG14084, Dm Bet1, Bet1" IPR000727:Target SNARE coiled-coil homology domain CG14084 11-Aug-17 DroID_v2017_08 "Drer\bet1, Drer\LOC103908618" "Scer\SFT1, Scer\BET1" Cele\nbet-1 "Xtro\bet1l, Xtro\LOC101730635, Xtro\bet1" "Mmus\Bet1l, Mmus\Bet1" "Hsap\BET1L, Hsap\BET1" FBgn0067757 l(1)G0068 lethal (1) G0068 http://flybase.org/reports/FBgn0067757 gene - - - l(1)G0068 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0052572 CG32572 - http://flybase.org/reports/FBgn0052572 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype - "CG13007, CG13006, CG32572" - CG32572 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,viable" "mushroom body alpha-lobe,mushroom body beta-lobe,adult mushroom body alpha'-lobe,adult mushroom body beta'-lobe" FBgn0060735 l(3)S067111b lethal (3) S067111b http://flybase.org/reports/FBgn0060735 gene - - - "0671/11, l(3)S067111b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033347 CG8248 - http://flybase.org/reports/FBgn0033347 protein_coding_gene - - - CG8248 - CG8248 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011092 l(1)Q52 lethal (1) Q52 http://flybase.org/reports/FBgn0011092 FBgn0010210 gene - - - l(1)Q52 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038144 CG8870 - http://flybase.org/reports/FBgn0038144 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP38, CG8870" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG8870 11-Aug-17 DroID_v2017_08 Drer\masp2 - "Cele\try-1, Cele\try-3" - Mmus\Klk1b5 Hsap\MASP2 viable FBgn0000451 ect ectodermal http://flybase.org/reports/FBgn0000451 "FBgn0010018, FBgn0036073, FBgn0036074" protein_coding_gene molecular_function ; GO:0003674 | no biological data available tube development ; GO:0035295 | inferred from expression pattern nucleus ; GO:0005634 | NOT inferred from direct assay cellular_component ; GO:0005575 | no biological data available "DROECT, Difl, Ifl, CG11965, CG6611, ect" - CG6611 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" mesothoracic tergum DRSC11343 I 0.372803533 1.64264382 1.157198897 0.428907946 1.197435646 0.768581437 FBgn0086401 BG02491 - http://flybase.org/reports/FBgn0086401 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02491 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0037719 bocks bocksbeutel http://flybase.org/reports/FBgn0037719 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "emerin, CG9424, Bocksbeutel, Bocks, bocks, bocksbeutel" "IPR003887:LEM domain, IPR011015:LEM/LEM-like domain" CG9424 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065202 l(2)SH2292 lethal (2) SH2292 http://flybase.org/reports/FBgn0065202 gene - - - "l(2)SH2292, l(2)SH2 2292" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033848 CG13330 - http://flybase.org/reports/FBgn0033848 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13330 - CG13330 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014164 fez freeze http://flybase.org/reports/FBgn0014164 - gene - male courtship behavior ; GO:0008049 | non-traceable author statement - fez - - 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,male,recessive,visible,mating defective" "eye,tergite,male" FBgn0023072 l(1)1Aj lethal (1) 1Aj http://flybase.org/reports/FBgn0023072 - gene - - - "1200C30b, l(1)1Aj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020362 anon-1C2 anon-1C2 http://flybase.org/reports/FBgn0020362 - gene - - - "1C2, anon-1C2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036468 CG13461 - http://flybase.org/reports/FBgn0036468 protein_coding_gene - - - CG13461 - CG13461 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0267927 CR46208 - http://flybase.org/reports/FBgn0267927 non_protein_coding_gene - - - "CR46208, lincRNA.93" - CR46208 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016071 sog::Xlae\chordin sog::Xlae\chordin http://flybase.org/reports/FBgn0016071 - engineered_fusion_gene - - - sog::Xlae\chordin - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065551 l(2)SH1035 lethal (2) SH1035 http://flybase.org/reports/FBgn0065551 gene - - - "l(2)SH1035, l(2)SH2 1035" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032815 CG10462 - http://flybase.org/reports/FBgn0032815 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "BcDNA:SD07008, CG10462" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10462 11-Aug-17 DroID_v2017_08 "Drer\LOC101883087, Drer\znfl2a" Scer\STP2 "Cele\ztf-23, Cele\blmp-1, Cele\lin-29, Cele\K10B3.5" - "Mmus\Wiz, Mmus\Zfp236" "Hsap\WIZ, Hsap\ZNF236" viable FBgn0264471 CR43879 - http://flybase.org/reports/FBgn0264471 non_protein_coding_gene - - - CR43879 - CR43879 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260936 scny scrawny http://flybase.org/reports/FBgn0260936 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VN55 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 positive regulation of chromatin silencing ; GO:0031937 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype histone H2B conserved C-terminal lysine deubiquitination ; GO:0035616 | inferred from direct assay inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from mutant phenotype positive regulation of stem cell population maintenance ; GO:1902459 | inferred from mutant phenotype somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype negative regulation of defense response to bacterium ; GO:1900425 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "scny, dUsp36, USP36, CG5505, l(3)02331, dUSP36, anon-WO0118547.247, mule, 2331, et, Usp36, Scny, Q9VRP5, usp36" "IPR018200:Ubiquitin specific protease, conserved site, IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR028889:Ubiquitin specific protease domain" CG5505 11-Aug-17 DroID_v2017_08 "Drer\usp42, Drer\usp49, Drer\usp36, Drer\usp44" "Scer\UBP10, Scer\UBP3, Scer\UBP16, Scer\UBP8, Scer\UBP1" "Cele\usp-3, Cele\usp-48, Cele\cyk-3, Cele\usp-33" "Xtro\usp44, Xtro\usp42, Xtro\usp36, Xtro\usp49, Xtro\usp3" "Mmus\Usp17ld, Mmus\Usp42, Mmus\Usp17la, Mmus\Usp17lb, Mmus\Usp17le, Mmus\Usp49, Mmus\Usp3, Mmus\Usp17lc, Mmus\Usp36" "Hsap\USP17L26, Hsap\USP17L1, Hsap\USP17L3, Hsap\USP17L15, Hsap\USP42, Hsap\USP17L24, Hsap\USP49, Hsap\USP17L27, Hsap\USP36, Hsap\USP17L17, Hsap\USP17L13, Hsap\USP17L7, Hsap\USP17L19, Hsap\USP17L2, Hsap\USP17L25, Hsap\USP17L20, Hsap\USP17L5, Hsap\USP17L28, Hsap\USP17L4, Hsap\USP17L11, Hsap\USP3, Hsap\USP17L10, Hsap\USP44, Hsap\USP17L8, Hsap\USP17L30, Hsap\USP17L22, Hsap\USP17L21, Hsap\USP17L12, Hsap\USP17L18, Hsap\USP17L29" pupal stage salivary gland

DRSC10509 IK -0.459841582 4.216582236 1.474476616 0.373148875 0.292412577 1.564232427 FBgn0024506 A359 A359 http://flybase.org/reports/FBgn0024506 - gene - - - A359 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016775 anon-73Bc anon-73Bc http://flybase.org/reports/FBgn0016775 - gene - - - "cDNA M, anon-73Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069194 l(2)hemo lethal (2) hemo http://flybase.org/reports/FBgn0069194 gene - - - l(2)hemo - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,melanotic mass phenotype" melanotic mass FBgn0065988 hrn heron http://flybase.org/reports/FBgn0065988 gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | traceable author statement cellular_component ; GO:0005575 | no biological data available hrn - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell number,somatic clone,neuroanatomy defective" "embryonic/larval mushroom body,somatic clone,adult mushroom body" FBgn0050506 tRNA:Thr-TGT-2-2 transfer RNA:Threonine-TGT 2-2 http://flybase.org/reports/FBgn0050506 tRNA_gene ACA codon-amino acid adaptor activity ; GO:0033439 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033439 cytosol ; GO:0005829 | inferred by curator from GO:0033439 "AE002787.trna25-ThrTGT, tRNA[Thr][[3]], tRNA:thr3:47F, tRNA:T3:47F, tRNA:T:TGT:AE002787-b, CR30258, CR30506, tRNA[[Thr]], chr2R.trna84-ThrTGT, tRNA-Thr-TGT-2-2, tRNA:Thr-TGT-2-2, tRNA:CR30506, ACA" - CR30506 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036915 Prp3 Precursor RNA processing 3 http://flybase.org/reports/FBgn0036915 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:17348 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000368237 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000003323 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype" U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000368237 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000003323 nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG7757, PRPF3, Prp3, dPrp3" "IPR013881:Pre-mRNA-splicing factor 3, IPR027104:U4/U6 small nuclear ribonucleoprotein Prp3, IPR010541:Domain of unknown function DUF1115" CG7757 11-Aug-17 DroID_v2017_08 "Drer\prpf3, Drer\ppp1r42" Scer\PRP3 Cele\prp-3 "Xtro\ppp1r42, Xtro\prpf3" "Mmus\Prpf3, Mmus\Ppp1r42" "Hsap\PPP1R42, Hsap\PRPF3" "lethal - all die before end of P-stage,some die during P-stage,lethal,partially lethal - majority die,visible" mesothoracic tergum DRSC10912 IE -0.930121959 2.676026069 -0.582410855 1.526208198 -1.216069414 -0.568723918 FBgn0022120 l(2)k06617 lethal (2) k06617 http://flybase.org/reports/FBgn0022120 - gene - - - l(2)k06617 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085300 Cpr65Ay Cuticular protein 65Ay http://flybase.org/reports/FBgn0085300 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr65Ay, CG34271" "IPR000618:Insect cuticle protein, IPR012674:Calycin, IPR031311:Chitin-binding type R&R consensus" CG34271 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - FBgn0015498 l(3)65CEb lethal (3) 65CEb http://flybase.org/reports/FBgn0015498 - gene - - - "XI, l(3)65CEb" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0026641 l(2)k09015a lethal (2) k09015a http://flybase.org/reports/FBgn0026641 - gene - - - "l(2)k09015, l(2)k09015a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "retina,somatic clone" FBgn0261243 Psa Puromycin sensitive aminopeptidase http://flybase.org/reports/FBgn0261243 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "dPSA, dPsa, CG1009, Psa, l(3)06226, PSA" "IPR024571:ERAP1-like C-terminal domain, IPR034016:Aminopeptidase N-type, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG1009 11-Aug-17 DroID_v2017_08 "Drer\lnpep, Drer\erap1a, Drer\si:ch211-149p5.1, Drer\si:ch211-276a23.5, Drer\si:ch211-106j24.1, Drer\erap2, Drer\anpepb, Drer\si:ch211-198g19.1, Drer\npepps, Drer\anpepa, Drer\erap1b, Drer\enpep" "Scer\TMA108, Scer\APE2, Scer\AAP1" "Cele\Y67D8C.9, Cele\R03G8.4, Cele\T16G12.1, Cele\R03G8.6, Cele\pam-1, Cele\T07F10.1, Cele\T12E12.6, Cele\F49B2.6" "Xtro\npepps, Xtro\erap1, Xtro\enpep, Xtro\lnpep, Xtro\anpep, Xtro\lvrn" "Mmus\Enpep, Mmus\Erap1, Mmus\Lvrn, Mmus\Lnpep, Mmus\Anpep, Mmus\Trhde, Mmus\Npepps" "Hsap\ENPEP, Hsap\ANPEP, Hsap\LNPEP, Hsap\ERAP2, Hsap\TRHDE, Hsap\NPEPPS, Hsap\LVRN, Hsap\ERAP1" FBgn0065113 mok mimic of kojak http://flybase.org/reports/FBgn0065113 gene molecular_function ; GO:0003674 | no biological data available antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mok - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002203 l(3)67BDa lethal (3) 67BDa http://flybase.org/reports/FBgn0002203 - gene - - - l(3)67BDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage,lethal,lethal - all die before end of larval stage,some die during larval stage" FBgn0030663 CG8117 - http://flybase.org/reports/FBgn0030663 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR017890 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001222" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR003618 neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "CG8117, dCrsp70" "IPR001222:Zinc finger, TFIIS-type, IPR003618:Transcription elongation factor S-II, central domain" CG8117 11-Aug-17 DroID_v2017_08 "Drer\tceanc2, Drer\si:dkey-33g10.1, Drer\tcea3, Drer\tcea1, Drer\tcea2, Drer\crsp7" "Scer\BYE1, Scer\DST1" "Cele\T24H10.1, Cele\mdt-26" "Xtro\tcea1, Xtro\tceanc2, Xtro\tceanc, Xtro\med26, Xtro\tcea3" "Mmus\Med26, Mmus\Stra6l, Mmus\Tceanc, Mmus\Tceanc2, Mmus\Tcea2, Mmus\Phf3, Mmus\Tcea1, Mmus\Tcea3" "Hsap\TCEANC, Hsap\TCEA1, Hsap\MED26, Hsap\PHF3, Hsap\TCEANC2, Hsap\TCEA2, Hsap\TCEA3" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0015927 demented demented http://flybase.org/reports/FBgn0015927 - gene - - - demented - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260575 MENE-DD3 - http://flybase.org/reports/FBgn0260575 gene - - - MENE-DD3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye disc,somatic clone" FBgn0003936 snRNA:U5:35D small nuclear RNA U5 at 35EF http://flybase.org/reports/FBgn0003936 FBgn0003932 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-35D, snRNA[[3]], K2, dU5, snRNA:U5:35EF, snRNA:U5, snRNA4, snRNA3, U5snRNA35EF, CR32877, U5snRNA, snRNA:U5:35D, U5:35D, U5 snRNA, U5 snRNA 35D" - CR32877 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065246 l(2)SH2138 lethal (2) SH2138 http://flybase.net/reports/FBgn0065246.html gene l(2)SH2 2138 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0014235 l(2)31Er lethal (2) 31Er http://flybase.org/reports/FBgn0014235 - gene - - - l(2)31Er - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024580 l(3)rM060 lethal (3) rM060 http://flybase.org/reports/FBgn0024580 - gene - - - l(3)rM060 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014154 e(S)X enhancer of S on X http://flybase.org/reports/FBgn0014154 - gene - - - e(S)X - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058459 28SrRNA:CR40459 28SrRNA:CR40459 http://flybase.org/reports/FBgn0058459 rRNA_gene - - - "CR40459, 28SrRNA:CR40459" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051249 CG31249 - http://flybase.org/reports/FBgn0051249 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Q9VEG8, CG7477, CG31249" IPR019265:Protein of unknown function UPF0568 CG31249 11-Aug-17 DroID_v2017_08 Drer\zgc:56576 - Cele\E02H1.5 Xtro\c14orf166 Mmus\2700060E02Rik Hsap\C14orf166 "viable,fertile,body color defective" mesothoracic tergum FBgn0023164 Su(mg)1-3 Suppressor of modifier of gypsy 1-3 http://flybase.org/reports/FBgn0023164 - gene - - - Su(mg)1-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001954 l(2)28Ac lethal (2) 28Ac http://flybase.org/reports/FBgn0001954 - gene - - - "L, l(2)28Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0019794 l(1)105 lethal (1) 105 http://flybase.org/reports/FBgn0019794 - gene - - - l(1)105 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052751 CG32751 - http://flybase.org/reports/FBgn0052751 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ; GO:0016811 | inferred from electronic annotation with InterPro:IPR012101 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from biological aspect of ancestor with PANTHER:PTN000064607" nitrogen compound metabolic process ; GO:0006807 | inferred from electronic annotation with InterPro:IPR003010 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3648, CG32751" "IPR003010:Carbon-nitrogen hydrolase, IPR012101:Biotinidase, eukaryotic" CG32751 11-Aug-17 DroID_v2017_08 "Drer\btd, Drer\nit2" "Scer\NIT3, Scer\NTA1" - "Xtro\nit2, Xtro\vnn1, Xtro\btd" "Mmus\Vnn1, Mmus\Nit2, Mmus\Btd, Mmus\Vnn3" "Hsap\VNN1, Hsap\VNN2, Hsap\NIT2, Hsap\VNN3, Hsap\BTD" FBgn0004232 l(3)93Bf lethal (3) 93Bf http://flybase.org/reports/FBgn0004232 - gene - - - "rlr4, l(3)93Bf" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0026370 SRPK SR Protein Kinase http://flybase.org/reports/FBgn0026370 "FBgn0034015, FBgn0064783" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000622883" peptidyl-serine phosphorylation ; GO:0018105 | inferred from direct assay karyosome formation ; GO:0030717 | inferred from mutant phenotype spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 spindle assembly involved in female meiosis ; GO:0007056 | inferred from mutant phenotype regulation of mRNA processing ; GO:0050684 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:11305 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:11305 "dSRPK1, CG8174, dSRPK, BcDNA:SD03158, SRPK, srpk, srpk79D" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG8174 11-Aug-17 DroID_v2017_08 "Drer\srpk3, Drer\srpk2, Drer\srpk1a, Drer\si:ch211-220i18.4, Drer\srpk1b" Scer\SKY1 Cele\spk-1 "Xtro\LOC100144966, Xtro\srpk2, Xtro\srpk3, Xtro\srpk1" "Mmus\Srpk2, Mmus\Srpk1, Mmus\Srpk3" "Hsap\SRPK3, Hsap\SRPK1, Hsap\SRPK2" "female sterile,viable,male sterile" "karyosome,meiotic spindleED2436),germline clone,chorion,chorion | germline clone,oocyte" FBgn0043841 vir-1 virus-induced RNA 1 http://flybase.org/reports/FBgn0043841 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from expression pattern - "CG31764, CG5453, BEST:GH02216, CG15493, vir-1, vir1, Vir-1, Vir1" - CG31764 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" embryonic/larval salivary gland DRSC02863 EK -0.168889965 0.24012127 2.588054971 -1.972258025 -1.506284053 0.387521769 FBgn0262148 CR42874 - http://flybase.org/reports/FBgn0262148 non_protein_coding_gene - - - CR42874 - CR42874 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266652 CR45159 - http://flybase.org/reports/FBgn0266652 non_protein_coding_gene - - - CR45159 - CR45159 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020856 fs(2)261505 female sterile(2)261505 http://flybase.org/reports/FBgn0020856 - gene - - - "fs(2)B, fs(2)261505" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0005426 l(1)adl15 lethal (1) adl15 http://flybase.org/reports/FBgn0005426 - gene - - - "l(1)adl-15, l(1)adl15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,short lived,partially lethal - majority die" FBgn0035855 CG7366 - http://flybase.org/reports/FBgn0035855 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.185, CG7366" - CG7366 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0036687 CG6652 - http://flybase.org/reports/FBgn0036687 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype axoneme ; GO:0005930 | inferred from direct assay CG6652 "IPR028933:Lebercilin domain, IPR026188:Lebercilin-like" CG6652 11-Aug-17 DroID_v2017_08 Drer\lca5 - - - "Mmus\Lca5l, Mmus\Lca5" "Hsap\LCA5, Hsap\LCA5L" viable FBgn0065224 l(2)SH2215 lethal (2) SH2215 http://flybase.org/reports/FBgn0065224 gene - - - "l(2)SH2215, l(2)SH2 2215" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034283 CG14492 - http://flybase.org/reports/FBgn0034283 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14492 IPR010512:Protein of unknown function DUF1091 CG14492 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0043483 l(3)66EFc lethal (3) 66EFc http://flybase.org/reports/FBgn0043483 gene - - - l(3)66EFc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0283724 Girdin Girdin http://flybase.org/reports/FBgn0283724 protein_coding_gene dynein light intermediate chain binding ; GO:0051959 | inferred from biological aspect of ancestor with PANTHER:PTN000436622 microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000436622 cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000436622 epithelium migration ; GO:0090132 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype dendrite development ; GO:0016358 | inferred from mutant phenotype epithelial cell-cell adhesion ; GO:0090136 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cytoskeleton-dependent intracellular transport ; GO:0030705 | inferred from biological aspect of ancestor with PANTHER:PTN000436622 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000436622 sensory dendrite ; GO:0071683 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000436622 spot adherens junction ; GO:0005914 | inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay zonula adherens ; GO:0005915 | inferred from direct assay "Girdin, CG12734, mecA" IPR008636:Hook-related protein family CG12734 11-Aug-17 DroID_v2017_08 "Drer\ccdc88aa, Drer\ccdc88b, Drer\ccdc88c, Drer\trappc2" - Cele\grdn-1 "Xtro\ccdc88c, Xtro\ccdc88a, Xtro\trappc2" "Mmus\Trappc2, Mmus\Ccdc88a, Mmus\0610009B22Rik, Mmus\Ccdc88c, Mmus\Ccdc88b" "Hsap\TRAPPC2, Hsap\CCDC88C, Hsap\CCDC88A, Hsap\CCDC88B" FBgn0023001 melt melted http://flybase.org/reports/FBgn0023001 FBgn0066864 protein_coding_gene phosphatidylinositol-5-phosphate binding ; GO:0010314 | inferred from direct assay phosphatidylinositol binding ; GO:0035091 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95V55 metabolic process ; GO:0008152 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype ectoderm development ; GO:0007398 | inferred from expression pattern sequestering of triglyceride ; GO:0030730 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok R8 cell fate specification ; GO:0045464 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "1441/14, anon-WO03014152.10, CG8624, melt, dMelt, Melt, Q9VS24_DROME" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG8624 11-Aug-17 DroID_v2017_08 Drer\veph1 - Cele\K10B4.3 Xtro\veph1 Mmus\Veph1 Hsap\VEPH1 "large body,small body,viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,size defective" "wing,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval nervous system,photoreceptor cell R8 of pale ommatidium,supernumerary,photoreceptor cell R8 of yellow ommatidium" FBgn0085713 CG41589 - http://flybase.org/reports/FBgn0085713 protein_coding_gene - - - CG41589 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032811 CG10268 - http://flybase.org/reports/FBgn0032811 protein_coding_gene phosphomevalonate kinase activity ; GO:0004631 | inferred from sequence or structural similarity with HGNC:9141 phosphomevalonate kinase activity ; GO:0004631 | inferred from biological aspect of ancestor with PANTHER:PTN000991923 "isoprenoid biosynthetic process ; GO:0008299 | inferred by curator from GO:0004631 cholesterol biosynthetic process ; GO:0006695 | inferred from biological aspect of ancestor with PANTHER:PTN000991923 cholesterol biosynthetic process ; GO:0006695 | inferred from sequence or structural similarity with HGNC:9141 isopentenyl diphosphate biosynthetic process, mevalonate pathway ; GO:0019287 | inferred from biological aspect of ancestor with PANTHER:PTN000991923" peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:9141 peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000991923 "BcDNA:SD12705, CG10268, MevPK" "IPR005919:Higher eukaryotic phosphomevalonate kinase, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10268 11-Aug-17 DroID_v2017_08 Drer\pmvk - Cele\F32D8.13 - Mmus\Pmvk Hsap\PMVK "partially lethal - majority die,some die during pupal stage" FBgn0036043 CG8177 - http://flybase.org/reports/FBgn0036043 protein_coding_gene "inorganic anion exchanger activity ; GO:0005452 | inferred from electronic annotation with InterPro:IPR001717, InterPro:IPR003020 anion transmembrane transporter activity ; GO:0008509 | inferred from biological aspect of ancestor with PANTHER:PTN000894242" bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000894302 anion transmembrane transport ; GO:0098656 | inferred from biological aspect of ancestor with PANTHER:PTN000894242 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000894242 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000894242 "anon-EST:Posey259, BcDNA:RE59468, CG8177, DAE" "IPR001717:Anion exchange protein, IPR003020:Bicarbonate transporter, eukaryotic, IPR011531:Bicarbonate transporter, C-terminal, IPR013769:Band 3 cytoplasmic domain, IPR016152:Phosphotransferase/anion transporter" CG8177 11-Aug-17 DroID_v2017_08 "Drer\slc4a11, Drer\slc4a5, Drer\slc4a2a, Drer\slc4a1b, Drer\slc4a1a, Drer\LOC557642, Drer\si:ch211-48m9.1, Drer\slc4a10a, Drer\slc4a4b, Drer\slc4a3, Drer\slc4a2b, Drer\slc4a7, Drer\slc4a8, Drer\slc4a4a" Scer\BOR1 "Cele\abts-1, Cele\abts-4, Cele\abts-3, Cele\abts-2" "Xtro\slc4a1, Xtro\slc4a5, Xtro\slc4a4, Xtro\slc4a8, Xtro\slc4a11, Xtro\slc4a7, Xtro\slc4a3, Xtro\slc4a10" "Mmus\Slc4a7, Mmus\Slc4a2, Mmus\Slc4a3, Mmus\Slc4a5, Mmus\Slc4a8, Mmus\Slc4a1, Mmus\Slc4a9, Mmus\Slc4a11, Mmus\Slc4a4, Mmus\Slc4a10" "Hsap\SLC4A1, Hsap\SLC4A9, Hsap\SLC4A5, Hsap\SLC4A11, Hsap\SLC4A3, Hsap\SLC4A4, Hsap\SLC4A7, Hsap\SLC4A8, Hsap\SLC4A10, Hsap\SLC4A2" viable FBgn0262237 mir-2491 mir-2491 stem loop http://flybase.org/reports/FBgn0262237 miRNA_gene - - - "mir-2491, CR42944, dme-mir-2491, miR-2491" - CR42944 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035880 Culd CUB and LDLa domain http://flybase.org/reports/FBgn0035880 protein_coding_gene - endocytosis ; GO:0006897 | inferred from mutant phenotype rhodopsin metabolic process ; GO:0046154 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype early endosome ; GO:0005769 | inferred from direct assay "CG17352, CT33100, Culd, cg17352, culd" "IPR000859:CUB domain, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG17352 11-Aug-17 DroID_v2017_08 "Drer\neto2b, Drer\ldlrad2, Drer\neto1" - "Cele\Y34D9A.8, Cele\mig-13" "Xtro\neto1, Xtro\neto2" "Mmus\Neto2, Mmus\Neto1" "Hsap\LDLRAD2, Hsap\NETO1, Hsap\NETO2" viable FBgn0033598 Cpr47Eb Cuticular protein 47Eb http://flybase.org/reports/FBgn0033598 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr47Eb, CG13224, DmelCpr47Eb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG13224 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0010168 reticulated reticulated http://flybase.org/reports/FBgn0010168 - gene - - - "dRet, ret, Dret2, reticulated" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,viable,male,reduced" "wing,wing vein,eye,postvertical bristle" FBgn0000012 abb abbreviated http://flybase.org/reports/FBgn0000012 - gene - - - abb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "macrochaeta,posterior scutellar bristle" FBgn0014964 gypsy\env gypsy\envelope http://flybase.org/reports/FBgn0014964 - transposable_element_gene - - - "DmeGypV env, ORF3, ENV, gypsy\env, env" IPR009882:Gypsy - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage && oogenesis stage follicle cell

adult stage && oogenesis stage follicle cell

FBgn0051891 CG31891 - http://flybase.org/reports/FBgn0051891 protein_coding_gene - - - CG31891 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002751 mit mitotic loss inducer http://flybase.org/reports/FBgn0002751 - gene - - - mit - - 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,viable,mitotic cell cycle defective,maternal effect,recessive" FBgn0033774 CG12374 - http://flybase.org/reports/FBgn0033774 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "anon-WO0140519.63, CG12374" "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG12374 11-Aug-17 DroID_v2017_08 "Drer\cpa5, Drer\cpo, Drer\cpa4, Drer\cpa2, Drer\cpa1, Drer\cpb2, Drer\cpb1, Drer\cpa6" Scer\ECM14 "Cele\suro-1, Cele\F02D8.4, Cele\T06A4.1, Cele\T06A4.3, Cele\ZC434.9, Cele\Y47G6A.19, Cele\W01A8.6, Cele\Y59C2A.1, Cele\Y18H1A.9" "Xtro\cpa3, Xtro\cpb2, Xtro\cpb1, Xtro\cpa1, Xtro\LOC100487462, Xtro\cpo" "Mmus\Cpa1, Mmus\Cpa2, Mmus\Cpa4, Mmus\Cpb1, Mmus\Cpa5, Mmus\Cpa6, Mmus\Cpb2, Mmus\Cpa3" "Hsap\CPA5, Hsap\CPA1, Hsap\CPB1, Hsap\CPA4, Hsap\CPB2, Hsap\CPA6, Hsap\CPA2, Hsap\CPO, Hsap\CPA3" viable FBgn0033356 CG8229 - http://flybase.org/reports/FBgn0033356 protein_coding_gene - - ELL-EAF complex ; GO:0032783 | inferred from physical interaction with Su(Tpl) inferred from physical interaction with Su(Tpl) inferred from physical interaction with Su(Tpl) "CG8229, Uspl1l" - CG8229 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0037472 CG10098 - http://flybase.org/reports/FBgn0037472 protein_coding_gene dipeptidase activity ; GO:0016805 | inferred from electronic annotation with InterPro:IPR005322 molecular_function ; GO:0003674 | no biological data available proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR005322 exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000313101 cellular_component ; GO:0005575 | no biological data available CG10098 "IPR005322:Peptidase C69, dipeptidase A" CG10098 11-Aug-17 DroID_v2017_08 "Drer\scrn2, Drer\scrn3" - - "Xtro\scrn3, Xtro\scrn2, Xtro\scrn1" "Mmus\Scrn3, Mmus\Scrn2, Mmus\Scrn1" "Hsap\SCRN1, Hsap\SCRN3, Hsap\SCRN2" viable FBgn0267665 CR46003 - http://flybase.org/reports/FBgn0267665 non_protein_coding_gene - - - "CR46003, Dm_3L:48631" - CR46003 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046679 anon-38C.1 anon-38C.1 http://flybase.org/reports/FBgn0046679 gene - - - "38C.1, anon-38C.1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005333 podG podoptera of Goldschmidt http://flybase.org/reports/FBgn0005333 - gene - - - "pod-G, podG" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0050090 CG30090 - http://flybase.org/reports/FBgn0050090 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP41, CG8215, BcDNA:GH21666, CG30090" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG30090 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.9, Drer\masp2, Drer\LOC558805, Drer\si:dkey-21e2.15, Drer\si:dkey-21e2.12, Drer\gzm3, Drer\si:dkey-21e2.7" - "Cele\try-3, Cele\try-1, Cele\try-5" - "Mmus\Cma2, Mmus\Mcpt4, Mmus\Klk6, Mmus\Gzmc, Mmus\Mcpt9, Mmus\Prss48, Mmus\Mcpt8, Mmus\Ctsg, Mmus\Gzmg, Mmus\Gzmb, Mmus\Cma1, Mmus\Gzme, Mmus\Gzmd, Mmus\Mcpt1, Mmus\Gzmf" "Hsap\CMA1, Hsap\GZMB, Hsap\GZMH, Hsap\CTSG" "viable,fertile" FBgn0260459 CG14106 - http://flybase.org/reports/FBgn0260459 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14106 "IPR027012:Enkurin domain, IPR027710:Enkurin domain-containing protein 1" CG14106 11-Aug-17 DroID_v2017_08 Drer\si:ch211-220d9.3 - - Xtro\enkd1 Mmus\Enkd1 Hsap\ENKD1 viable FBgn0014064 Su(tor)3-293 Su(tor)3-293 http://flybase.org/reports/FBgn0014064 - gene - - - Su(tor)3-293 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028515 EndoGI Endonuclease G inhibitor http://flybase.org/reports/FBgn0028515 protein_coding_gene "hydrolase activity, acting on acid anhydrides ; GO:0016817 | inferred from electronic annotation with InterPro:IPR014893 ribonuclease inhibitor activity ; GO:0008428 | inferred from direct assay telomeric DNA binding ; GO:0042162 | inferred from biological aspect of ancestor with PANTHER:PTN000288287" telomere maintenance ; GO:0000723 | inferred from biological aspect of ancestor with PANTHER:PTN000288287 negative regulation of endoribonuclease activity ; GO:0060702 | inferred from direct assay motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype "nucleus ; GO:0005634 | inferred from direct assay nuclear chromosome, telomeric region ; GO:0000784 | inferred from biological aspect of ancestor with PANTHER:PTN000288287" "BG:DS07473.2, endoGI, EndoGI, dEndoGI, CG4930" "IPR014893:Ku, C-terminal" CG4930 11-Aug-17 DroID_v2017_08 Drer\xrcc5 Scer\YKU80 Cele\cku-80 - Mmus\Xrcc5 Hsap\XRCC5 "flight defective,visible,somatic clone,increased cell number,neuroanatomy defective,partially lethal - majority die,some die during third instar larval stage,uncoordinated,small body,lethal,recessive,male sterile,female fertile" "eye,somatic clone,wing disc,wing,posterior,wing vein,wing margin bristle,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,segmental nerve branch SNc of A1-7,intersegmental nerve,leg" FBgn0085470 lmgB lemming B http://flybase.org/reports/FBgn0085470 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lmgB, ORF2, CG34441, Dromel_CG18042_FBtr0079695_lmg_mORF, APC11" - CG34441 11-Aug-17 DroID_v2017_08 "Drer\fam89b, Drer\fam89a, Drer\anapc11" Scer\APC11 - - "Mmus\Anapc11, Mmus\Fam89a, Mmus\Fam89b" "Hsap\FAM89B, Hsap\FAM89A, Hsap\ANAPC11" FBgn0023426 sauf sauf http://flybase.org/reports/FBgn0023426 - gene - - - sauf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0065290 l(2)SH2013 lethal (2) SH2013 http://flybase.org/reports/FBgn0065290 gene - - - "l(2)SH2013, l(2)SH2 2013" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260257 GSd471 - http://flybase.org/reports/FBgn0260257 gene - - - GSd471 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034375 CG12613 - http://flybase.org/reports/FBgn0034375 protein_coding_gene - - - CG12613 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033763 CG8646 - http://flybase.org/reports/FBgn0033763 protein_coding_gene sulfuric ester hydrolase activity ; GO:0008484 | inferred from electronic annotation with InterPro:IPR000917 "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850" - CG8646 "IPR000917:Sulfatase, N-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site" CG8646 11-Aug-17 DroID_v2017_08 "Drer\LOC101884179, Drer\galns, Drer\arsa, Drer\arsg, Drer\arsia, Drer\arsh, Drer\LOC563783, Drer\sgsh, Drer\ids, Drer\LOC559800, Drer\si:dkey-174i8.1" - Cele\sul-3 "Xtro\sts, Xtro\arsa.1, Xtro\sgsh, Xtro\arsb, Xtro\arsi, Xtro\ids, Xtro\arsk, Xtro\arsj, Xtro\arsh, Xtro\arsd" "Mmus\Ids, Mmus\Galns, Mmus\Arsj, Mmus\Arsa, Mmus\Sgsh, Mmus\Arsb, Mmus\Arsi, Mmus\Arsg" "Hsap\ARSH, Hsap\ARSA, Hsap\IDS, Hsap\ARSF, Hsap\SGSH, Hsap\ARSE, Hsap\ARSD, Hsap\ARSB, Hsap\ARSG, Hsap\STS, Hsap\ARSI, Hsap\GALNS, Hsap\ARSJ" lethal FBgn0040182 l(1)G0279 lethal (1) G0279 http://flybase.org/reports/FBgn0040182 gene - - - l(1)G0279 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002534 Lcp3 Larval cuticle protein 3 http://flybase.org/reports/FBgn0002534 - protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from direct assay larval chitin-based cuticle development ; GO:0008363 | inferred by curator from GO:0008010 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from direct assay "DMLCP3, LcpIII, L[[3]]CP3, LCP-3, 3, III, CP3, LCP3, CG2043, Lcp3, DmelLcp3, lcp3" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2043 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | third instar stage 2 , larval stage | late third instar larval stage " " integumentary system

, organism

" "electrophoretic variant,viable" FBgn0262005 CG42823 - http://flybase.org/reports/FBgn0262005 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG34053, CG42823, HDC14119, BP1087" IPR002350:Kazal domain CG42823 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021916 l(2)k11328 lethal (2) k11328 http://flybase.org/reports/FBgn0021916 - gene - - - "l(2)113/28, l(2)k11328" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043578 PGRP-SB1 Peptidoglycan recognition protein SB1 http://flybase.org/reports/FBgn0043578 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | inferred from sequence or structural similarity with PGRP-SC1b N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | inferred from direct assay innate immune response ; GO:0045087 | inferred from electronic annotation with InterPro:IPR017331 innate immune response ; GO:0045087 | non-traceable author statement peptidoglycan catabolic process ; GO:0009253 | inferred from sequence or structural similarity with PGRP-SC1b immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement extracellular region ; GO:0005576 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay "PGRP-SB1, 142657_at, PGRP SB1, CG9681, PGRP-SB" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR017331:Peptidoglycan recognition protein, PGRP-S" CG9681 11-Aug-17 DroID_v2017_08 "Drer\pglyrp5, Drer\pglyrp2, Drer\pglyrp6" - - "Xtro\pglyrp1, Xtro\pglyrp1, Xtro\pglyrp2" "Mmus\Pglyrp3, Mmus\Pglyrp4, Mmus\Pglyrp2, Mmus\Pglyrp1" "Hsap\PGLYRP1, Hsap\PGLYRP3, Hsap\PGLYRP4, Hsap\PGLYRP2" FBgn0000221 brn brainiac http://flybase.org/reports/FBgn0000221 FBgn0005387 protein_coding_gene "galactosyltransferase activity ; GO:0008378 | inferred from electronic annotation with InterPro:IPR002659 beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity ; GO:0046981 | inferred from direct assay acetylglucosaminyltransferase activity ; GO:0008375 | traceable author statement" protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR002659 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement optic lobe placode formation ; GO:0001744 | inferred from mutant phenotype ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype glycosphingolipid biosynthetic process ; GO:0006688 | traceable author statement glycosphingolipid biosynthetic process ; GO:0006688 | inferred from direct assay germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype maintenance of polarity of follicular epithelium ; GO:0042248 | inferred from mutant phenotype oogenesis ; GO:0048477 | non-traceable author statement morphogenesis of follicular epithelium ; GO:0016333 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 Golgi stack ; GO:0005795 | inferred from sequence or structural similarity with UniProtKB:Q24342 extracellular region ; GO:0005576 | inferred from sequence or structural similarity "brc, l(1)6P6, fs(1)107, fs(1)A107, EG:EG0007.6, CG4934, brn, Brn" "IPR002659:Glycosyl transferase, family 31, IPR029044:Nucleotide-diphospho-sugar transferases" CG4934 11-Aug-17 DroID_v2017_08 "Drer\b3galnt2, Drer\b3gnt9, Drer\b3gnt2l, Drer\zgc:194551, Drer\b3gnt5a, Drer\si:ch211-126g16.11, Drer\si:ch211-126g16.10, Drer\b3gnt7l, Drer\b3gnt5b, Drer\si:dkey-175m17.6, Drer\b3gnt7, Drer\LOC100535930, Drer\zgc:194330, Drer\b3galt1b, Drer\si:dkey-160o24.3, Drer\b3gnt2b, Drer\b3galt1a, Drer\zgc:86586, Drer\b3gnt2a, Drer\b3galt2, Drer\b3gnt3, Drer\LOC565422" - "Cele\C54C8.3, Cele\B0024.15, Cele\C47F8.6, Cele\bus-17, Cele\C47F8.5, Cele\bre-5, Cele\F14B6.4, Cele\bus-2" "Xtro\LOC100487553, Xtro\b3galt1, Xtro\LOC100493833, Xtro\b3gnt6, Xtro\b3gnt3, Xtro\LOC100494668, Xtro\b3gnt5, Xtro\b3gnt3, Xtro\b3galt4, Xtro\b3gnt4, Xtro\b3galt2, Xtro\b3galnt2, Xtro\LOC100494986, Xtro\LOC100489267, Xtro\b3gnt2" "Mmus\B3gnt3, Mmus\B3gnt2, Mmus\B3gnt9, Mmus\B3gnt6, Mmus\B3galnt1, Mmus\B3gnt4, Mmus\B3galnt2, Mmus\B3gnt7, Mmus\B3galt2, Mmus\B3galt4, Mmus\B3gnt8, Mmus\B3galt5, Mmus\B3galt1, Mmus\B3gnt5" "Hsap\B3GALT2, Hsap\B3GALNT2, Hsap\B3GNT5, Hsap\B3GALNT1, Hsap\B3GNT2, Hsap\B3GALT4, Hsap\B3GNT6, Hsap\B3GNT7, Hsap\B3GNT3, Hsap\B3GALT1, Hsap\B3GALT5, Hsap\B3GNT8, Hsap\B3GNT9, Hsap\B3GNT4" " adult stage && oogenesis stage , adult stage , oogenesis stage , embryonic stage " germarium | restricted

"lethal,rescuable maternal effect,cold sensitive,neurogenic phenotype,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,heat sensitive,neuroanatomy defective,female sterile,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage" "follicle cell,dorsal appendage,cold sensitive,germline cell,female,ovary,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina plexus" FBgn0260041 siren6 siren 6 http://flybase.org/reports/FBgn0260041 gene - - - siren6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0069415 JJF157 JJF157 http://flybase.org/reports/FBgn0069415 gene - - - JJF157 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0037881 GCC88 GRIP and coiled-coil domain containing 88 kDa http://flybase.org/reports/FBgn0037881 protein_coding_gene "protein homodimerization activity ; GO:0042803 | inferred from sequence model Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2, Rab19, Rab6, Rab30 ADP-ribosylation factor binding ; GO:0030306 | inferred from physical interaction with Arl1" "protein targeting to Golgi ; GO:0000042 | inferred from electronic annotation with InterPro:IPR000237 Golgi vesicle transport ; GO:0048193 | inferred by curator from GO:0000138,GO:0017137" Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi trans cisterna ; GO:0000138 | inferred from direct assay "CG10703, dGCC88, GCC88" IPR000237:GRIP domain CG10703 11-Aug-17 DroID_v2017_08 Drer\gcc1 - Cele\gcc-1 Xtro\gcc1 Mmus\Gcc1 Hsap\GCC1 viable DRSC29299 K 0.380894362 0.101980666 0.292371011 0.106995776 -1.664256578 0.233616632 FBgn0040074 retinin retinin http://flybase.org/reports/FBgn0040074 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from direct assay "CG13057, retinin, 4A11" IPR007614:Retinin-like protein CG13057 11-Aug-17 DroID_v2017_08 Drer\tmem38a - - "Xtro\tmem38a, Xtro\tmem38b" "Mmus\Tmem38a, Mmus\Tmem38b" "Hsap\TMEM38A, Hsap\TMEM38B" FBgn0065271 l(2)SH2057 lethal (2) SH2057 http://flybase.org/reports/FBgn0065271 gene - - - "l(2)SH2057, l(2)SH2 2057" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065624 l(2)SH0798 lethal (2) SH0798 http://flybase.org/reports/FBgn0065624 gene - - - "l(2)SH0798, l(2)SH2 0798" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035064 TyrRS-m "Tyrosyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0035064 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002305, InterPro:IPR002307 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002942 tyrosine-tRNA ligase activity ; GO:0004831 | inferred from sequence or structural similarity with HGNC:24249 tyrosine-tRNA ligase activity ; GO:0004831 | traceable author statement" tyrosyl-tRNA aminoacylation ; GO:0006437 | traceable author statement mitochondrial tyrosyl-tRNA aminoacylation ; GO:0070184 | inferred from sequence or structural similarity with HGNC:24249 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000205414 mitochondrion ; GO:0005739 | traceable author statement mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:1917370 "anon-EST:fe1E12, CG16912, Aatm, TyrRS-m, Aats-tyr-m" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002305:Aminoacyl-tRNA synthetase, class Ic, IPR002307:Tyrosine-tRNA ligase, IPR024088:Tyrosine-tRNA ligase, bacterial-type, IPR024107:Tyrosine-tRNA ligase, bacterial-type, type 1, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR002942:RNA-binding S4 domain" CG16912 11-Aug-17 DroID_v2017_08 Drer\yars2 Scer\MSY1 Cele\yars-2 Xtro\yars2 Mmus\Yars2 Hsap\YARS2 "viable,visible" trichogen cell FBgn0065171 l(3)SH023 lethal (3) SH023 http://flybase.org/reports/FBgn0065171 gene - - - "l(3)SH023, l(2)SH3 023" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015906 atx abortex http://flybase.org/reports/FBgn0015906 - gene - - - atx - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,rescuable maternal effect" "epidermis,ventral" FBgn0035316 CG15878 - http://flybase.org/reports/FBgn0035316 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15878, 15878" - CG15878 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08486 K 0.272749717 0.133171915 0.672399514 -0.172274909 -0.185288507 1.67590223 FBgn0030005 CG2120 - http://flybase.org/reports/FBgn0030005 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG2120 IPR013087:Zinc finger C2H2-type CG2120 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-40k21.9, Drer\si:dkey-182i3.9, Drer\si:ch73-389k6.1, Drer\LOC108183284, Drer\zgc:113295, Drer\LOC108183935, Drer\znf1168, Drer\znf1184, Drer\si:dkey-33c14.6, Drer\zgc:113364, Drer\zgc:173548, Drer\znf1069, Drer\LOC798048, Drer\si:ch73-109d9.2, Drer\znf1041, Drer\zgc:171551, Drer\znf1169, Drer\zgc:112998, Drer\arl14ep, Drer\blf, Drer\si:ch73-92e7.6, Drer\zgc:101562, Drer\si:dkey-182i3.10, Drer\znf1070, Drer\thap3, Drer\znf983, Drer\si:dkey-228b2.6, Drer\thap1, Drer\si:ch73-367f21.6, Drer\znf569l" Scer\PZF1 Cele\let-391 "Xtro\znf33b, Xtro\znf850, Xtro\znf350, Xtro\thap1, Xtro\thap5, Xtro\znf470" "Mmus\Zfp35, Mmus\Zfp958, Mmus\Zfp239, Mmus\Zfp61, Mmus\Zfp677, Mmus\Zfp112, Mmus\Zfp617, Mmus\Zfp93, Mmus\Zfp114, Mmus\Zfp111, Mmus\Thap3, Mmus\Thap2, Mmus\Zfp719, Mmus\Zfp182, Mmus\Gm6710, Mmus\Zfp108, Mmus\Zfp235, Mmus\Zfp975, Mmus\Zfp109, Mmus\Zfp689, Mmus\Zfp658, Mmus\Thap1, Mmus\Zfp2, Mmus\Rslcan18, Mmus\Zfp53, Mmus\Zbtb24, Mmus\Zfp46, Mmus\Zfp51, Mmus\Zfp664, Mmus\Zfp94, Mmus\Zfp616" "Hsap\ZNF233, Hsap\ZNF565, Hsap\ZNF239, Hsap\ZNF155, Hsap\ZBTB24, Hsap\ZNF287, Hsap\ZNF93, Hsap\ZNF284, Hsap\ZNF774, Hsap\ZNF235, Hsap\ZNF544, Hsap\ZNF45, Hsap\ZNF300, Hsap\ZNF689, Hsap\ZNF493, Hsap\ZNF214, Hsap\ZNF835, Hsap\ZNF224, Hsap\ZNF234, Hsap\THAP1, Hsap\ZNF665, Hsap\ZNF664, Hsap\ZNF285, Hsap\ZNF567, Hsap\THAP5, Hsap\ZNF229, Hsap\ZNF717, Hsap\ZNF616, Hsap\ZNF700, Hsap\ZNF222, Hsap\ZNF675, Hsap\ZNF227, Hsap\ZNF71, Hsap\ZNF85, Hsap\ZNF630, Hsap\ZNF225, Hsap\THAP2, Hsap\ZNF226, Hsap\ZFP2, Hsap\ZNF182, Hsap\ZNF283, Hsap\ZNF497, Hsap\ZNF624, Hsap\THAP3, Hsap\THAP8, Hsap\ZNF836, Hsap\ZNF223" viable FBgn0034011 CG8160 - http://flybase.org/reports/FBgn0034011 protein_coding_gene - - extracellular region ; GO:0005576 | inferred from direct assay CG8160 - CG8160 11-Aug-17 DroID_v2017_08 Drer\ubqln4 Scer\DSK2 Cele\ubql-1 - "Mmus\Ubqln2, Mmus\Ubqln4, Mmus\Ubqln1" "Hsap\UBQLN4, Hsap\UBQLN2, Hsap\UBQLN1" "partially lethal - majority die,some die during pupal stage" FBgn0038151 yellow-e2 yellow-e2 http://flybase.org/reports/FBgn0038151 protein_coding_gene - cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG17044, yellow-e2, yel-e2, e2" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG17044 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002493 l(3)SG53 lethal (3) SG53 http://flybase.org/reports/FBgn0002493 - gene - - - "l(3)1803 R16, l(3)SG53" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0051870 CG31870 - http://flybase.org/reports/FBgn0051870 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs28a02.y1, bs19e04.y1, NEST:bs19e04, NEST:bs28a02, BcDNA:AT11120, CG31870" IPR010736:Sperm-tail PG-rich repeat CG31870 11-Aug-17 DroID_v2017_08 "Drer\odf3l2, Drer\zgc:110183" - - - "Mmus\Odf3l2, Mmus\Odf3l1" "Hsap\ODF3L2, Hsap\ODF3L1" FBgn0031201 CG12446 - http://flybase.org/reports/FBgn0031201 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from biological aspect of ancestor with PANTHER:PTN001076968 cellular_component ; GO:0005575 | no biological data available CG12446 "IPR005240:Protein of unknown function DUF389, IPR020846:Major facilitator superfamily domain" CG12446 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040837 CG8620 - http://flybase.org/reports/FBgn0040837 protein_coding_gene - - - CG8620 - CG8620 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067785 anon-i232 anon-i232 http://flybase.org/reports/FBgn0067785 gene - - - "i232, XM080537.1, anon-i232" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063783 l(3)8B lethal (3) 8B http://flybase.org/reports/FBgn0063783 gene - - - l(3)8B - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065789 l(2)SH0431 lethal (2) SH0431 http://flybase.org/reports/FBgn0065789 gene - - - "l(2)SH0431, l(2)SH2 0431" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037046 CG10581 - http://flybase.org/reports/FBgn0037046 protein_coding_gene "nucleotide phosphatase activity, acting on free nucleotides ; GO:0098519 | inferred from electronic annotation with InterPro:IPR004948" imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - CG10581 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR004948:Nucleoside-triphosphatase, THEP1 type" CG10581 11-Aug-17 DroID_v2017_08 Drer\ntpcr - - Xtro\ntpcr Mmus\Ntpcr Hsap\NTPCR viable FBgn0085254 CG34225 - http://flybase.org/reports/FBgn0085254 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34225 - CG34225 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002954 nofI no object fixation I http://flybase.org/reports/FBgn0002954 - gene - - - nofI - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,visual behavior defective" "rhabdomere | adult stage,pigment cell,optic lobe" FBgn0014051 Su(tor)2-280 Su(tor)2-280 http://flybase.org/reports/FBgn0014051 - gene - - - Su(tor)2-280 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053357 5SrRNA:CR33357 5SrRNA:CR33357 http://flybase.org/reports/FBgn0053357 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33357, 5SrRNA:CR33357" - CR33357 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082599 bek bek http://flybase.org/reports/FBgn0082599 gene - - - bek - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage" "metathoracic ventral denticle belt,germline clone,maternal effect,embryonic segment,stage 5 embryo" FBgn0051953 CR31953 - http://flybase.org/reports/FBgn0051953 pseudogene_attribute - - - "CG31953, CR31953" - CR31953 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039054 Cow Carrier of Wingless http://flybase.org/reports/FBgn0039054 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR019577 Wnt-protein binding ; GO:0017147 | inferred from physical interaction with wg" regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype extracellular transport ; GO:0006858 | inferred from mutant phenotype establishment of protein localization to extracellular region ; GO:0035592 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR019577 extracellular space ; GO:0005615 | inferred from direct assay "CG13830, Cow, cow" "IPR000716:Thyroglobulin type-1, IPR002350:Kazal domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR019577:SPARC/Testican, calcium-binding domain" CG13830 11-Aug-17 DroID_v2017_08 "Drer\cd74a, Drer\spock3, Drer\spock2" - Cele\test-1 "Xtro\spock2, Xtro\cd74, Xtro\spock3" "Mmus\Spock1, Mmus\Spock2, Mmus\Spock3, Mmus\Cd74" "Hsap\SPOCK2, Hsap\CD74, Hsap\SPOCK3, Hsap\SPOCK1" viable FBgn0023079 h::kni h::kni http://flybase.org/reports/FBgn0023079 - engineered_fusion_gene - - - h::kni - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially" FBgn0036646 CR18217 - http://flybase.org/reports/FBgn0036646 pseudogene_attribute - - - "CG18217, CR18217" - CR18217 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031488 CG17265 - http://flybase.org/reports/FBgn0031488 protein_coding_gene - RNA interference ; GO:0016246 | inferred from mutant phenotype - CG17265 IPR019359:CCDC85 family CG17265 11-Aug-17 DroID_v2017_08 "Drer\ccdc85a, Drer\ccdc85ca, Drer\ccdc85cb, Drer\ccdc85al, Drer\ccdc85b" - Cele\picc-1 "Xtro\ccdc85b, Xtro\ccdc85c, Xtro\ccdc85a" "Mmus\Ccdc85b, Mmus\Ccdc85c, Mmus\Ccdc85a" "Hsap\CCDC85C, Hsap\CCDC85A, Hsap\CCDC85B" lethal FBgn0032313 CG14070 - http://flybase.org/reports/FBgn0032313 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002995 CG14070 IPR002995:Surfeit locus 4 CG14070 11-Aug-17 DroID_v2017_08 Drer\surf4l Scer\ERV29 Cele\T02E1.7 "Xtro\surf4.1, Xtro\surf4.2" Mmus\Surf4 Hsap\SURF4 viable FBgn0259451 C325 - http://flybase.org/reports/FBgn0259451 gene - - - C325 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0003413 siw side wings http://flybase.org/reports/FBgn0003413 - gene - - - siw - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male,reduced,male sterile,recessive,visible" wing FBgn0004414 msopa male-specific opa containing gene http://flybase.org/reports/FBgn0004414 FBgn0040640 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response ; GO:0006952 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG14560, msopa" - CG14560 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal" FBgn0267886 CR46174 - http://flybase.org/reports/FBgn0267886 pseudogene_attribute - - - CR46174 - CR46174 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050177 CG30177 - http://flybase.org/reports/FBgn0050177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30177 IPR004345:TB2/DP1/HVA22-related protein CG30177 11-Aug-17 DroID_v2017_08 "Drer\reep3a, Drer\reep2, Drer\reep1, Drer\reep3b" - "Cele\W01D2.3, Cele\Y110A2AR.1, Cele\T19C3.4, Cele\C06E1.1" "Xtro\reep3, Xtro\reep4" "Mmus\Reep3, Mmus\Reep4, Mmus\Reep1, Mmus\Reep2" "Hsap\REEP4, Hsap\REEP3, Hsap\REEP2, Hsap\REEP1" viable FBgn0262619 DNA-ligI DNA ligase I http://flybase.org/reports/FBgn0262619 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000977, InterPro:IPR012310 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR012308 DNA ligase (ATP) activity ; GO:0003910 | inferred from direct assay" "DNA biosynthetic process ; GO:0071897 | inferred from electronic annotation with InterPro:IPR000977 DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR000977, InterPro:IPR012308, InterPro:IPR012309, InterPro:IPR012310 DNA ligation involved in DNA repair ; GO:0051103 | inferred from electronic annotation with InterPro:IPR016059 Okazaki fragment processing involved in mitotic DNA replication ; GO:1903461 | inferred from biological aspect of ancestor with PANTHER:PTN000048794" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000048763 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000048763 cytoplasm ; GO:0005737 | inferred from direct assay nuclear replication fork ; GO:0043596 | NOT inferred from direct assay "CG5602, DNA-ligI, DmDNA Lig I, LIG1" "IPR000977:DNA ligase, ATP-dependent, IPR012309:DNA ligase, ATP-dependent, C-terminal, IPR012310:DNA ligase, ATP-dependent, central, IPR012340:Nucleic acid-binding, OB-fold, IPR016059:DNA ligase, ATP-dependent, conserved site, IPR012308:DNA ligase, ATP-dependent, N-terminal" CG5602 11-Aug-17 DroID_v2017_08 Drer\lig1 Scer\CDC9 Cele\lig-1 Xtro\lig1 Mmus\Lig1 Hsap\LIG1 embryonic stage | early-mid FBgn0058470 CG40470 - http://flybase.org/reports/FBgn0058470 protein_coding_gene peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 CG40470 "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG40470 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-106j24.1, Drer\si:ch211-149p5.1, Drer\anpepa, Drer\lnpep, Drer\anpepb, Drer\erap1a, Drer\enpep, Drer\erap2, Drer\npepps, Drer\erap1b, Drer\si:ch211-198g19.1, Drer\si:ch211-276a23.5" "Scer\APE2, Scer\AAP1, Scer\TMA108" "Cele\mnp-1, Cele\VB0395L.1, Cele\AC3.5, Cele\T12E12.6, Cele\F49B2.6, Cele\T16G12.1, Cele\T07F10.1, Cele\R03G8.6, Cele\Y67D8C.9, Cele\pam-1, Cele\R03G8.4, Cele\Y42A5A.1, Cele\Y53F4B.20" "Xtro\npepps, Xtro\erap1, Xtro\anpep, Xtro\lvrn, Xtro\enpep, Xtro\lnpep" "Mmus\Npepps, Mmus\Anpep, Mmus\Lnpep, Mmus\Erap1, Mmus\Trhde, Mmus\Enpep, Mmus\Lvrn" "Hsap\NPEPPS, Hsap\TRHDE, Hsap\ENPEP, Hsap\LVRN, Hsap\ERAP1, Hsap\ANPEP, Hsap\ERAP2, Hsap\LNPEP" FBgn0065782 l(2)SH0441 lethal (2) SH0441 http://flybase.org/reports/FBgn0065782 gene - - - "l(2)SH0441, l(2)SH2 0441" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265164 CR44233 - http://flybase.org/reports/FBgn0265164 non_protein_coding_gene - - - CR44233 - CR44233 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086370 sra sarah http://flybase.org/reports/FBgn0086370 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 calcium-dependent protein serine/threonine phosphatase regulator activity ; GO:0008597 | inferred from biological aspect of ancestor with PANTHER:PTN000033709 protein binding ; GO:0005515 | inferred from physical interaction with Pp2B-14D inferred from physical interaction with CanB2 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24214 inferred from physical interaction with UniProtKB:Q27889 inferred from physical interaction with UniProtKB:Q9VXF1 "long-term memory ; GO:0007616 | inferred from mutant phenotype regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from genetic interaction with Pp2B-14D female meiotic division ; GO:0007143 | inferred from mutant phenotype regulation of female receptivity, post-mating ; GO:0046008 | inferred from mutant phenotype male pronucleus assembly ; GO:0035039 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from direct assay egg activation ; GO:0007343 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype regulation of calcineurin-NFAT signaling cascade ; GO:0070884 | inferred from mutant phenotype" mitochondrial matrix ; GO:0005759 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "sra, nla, CG6072, 89B11, 89B, anon-WO0172774.10, anon-WO0118547.92, l(3)05203, nebula, Sra" "IPR006931:Calcipressin, IPR000504:RNA recognition motif domain" CG6072 11-Aug-17 DroID_v2017_08 "Drer\rcan2, Drer\pycard, Drer\rcan3, Drer\rcan1b, Drer\rcan1a" Scer\RCN1 Cele\rcan-1 "Xtro\rcan1, Xtro\rcan2" "Mmus\Rcan3, Mmus\Rcan1, Mmus\Rcan2" "Hsap\RCAN2, Hsap\RCAN3, Hsap\RCAN1" FBgn0021832 l(2)k15826 lethal (2) k15826 http://flybase.org/reports/FBgn0021832 - gene - - - l(2)k15826 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065826 l(2)SH0359 lethal (2) SH0359 http://flybase.org/reports/FBgn0065826 gene - - - "l(2)SH0359, l(2)SH2 0359" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033389 Rad51D Rad51 recombinase D http://flybase.org/reports/FBgn0033389 protein_coding_gene four-way junction DNA binding ; GO:0000400 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 endodeoxyribonuclease activity ; GO:0004520 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001415033 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from sequence or structural similarity with HGNC:9817 DNA-dependent ATPase activity ; GO:0008094 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 strand invasion ; GO:0042148 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 DNA recombination ; GO:0006310 | inferred from sequence or structural similarity with HGNC:9817 reciprocal meiotic recombination ; GO:0007131 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 meiotic DNA recombinase assembly ; GO:0000707 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with HGNC:9817 mitotic recombination ; GO:0006312 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 response to ionizing radiation ; GO:0010212 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 Rad51B-Rad51C-Rad51D-XRCC2 complex ; GO:0033063 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 replication fork ; GO:0005657 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 "Dm CG2412, CG2412, dmRad51C, Rad51C, Rad51D" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013632:DNA recombination and repair protein Rad51-like, C-terminal" CG2412 11-Aug-17 DroID_v2017_08 "Drer\rad51, Drer\dmc1, Drer\rad51d, Drer\rad51b" "Scer\RAD51, Scer\RAD57" "Cele\rad-51, Cele\rfs-1" "Xtro\rad51, Xtro\rad51d" "Mmus\Rad51d, Mmus\Rad51, Mmus\Rad51b, Mmus\Dmc1" "Hsap\RAD51B, Hsap\DMC1, Hsap\RAD51, Hsap\RAD51D" viable FBgn0033296 Mal-A7 Maltase A7 http://flybase.org/reports/FBgn0033296 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "CT36683, Mal-A7, CG11669, mal_A7, Drome_A7" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG11669 11-Aug-17 DroID_v2017_08 "Drer\slc3a2a, Drer\slc3a1, Drer\si:dkey-202g17.3, Drer\zgc:158423, Drer\slc3a2b" "Scer\IMA5, Scer\MAL12, Scer\IMA1, Scer\IMA2, Scer\IMA3, Scer\IMA4, Scer\MAL32" "Cele\atgp-1, Cele\atgp-2" "Xtro\slc3a1, Xtro\slc3a2" "Mmus\Slc3a1, Mmus\Slc3a2" "Hsap\SLC3A1, Hsap\SLC3A2, Hsap\GBE1" viable FBgn0034755 CG3746 - http://flybase.org/reports/FBgn0034755 protein_coding_gene - - - CG3746 - CG3746 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036881 Cpr76Bd Cuticular protein 76Bd http://flybase.org/reports/FBgn0036881 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr76Bd, CG9299, DmelCpr76Bd" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG9299 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" tergite FBgn0264367 CR43819 - http://flybase.org/reports/FBgn0264367 non_protein_coding_gene - - - "CR43819, lincRNA.168" - CR43819 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020784 sDBP-X satellite DNA binding protein X http://flybase.org/reports/FBgn0020784 - gene DNA binding ; GO:0003677 | inferred from direct assay - - "pX, sDBP-X" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266885 CR45346 - http://flybase.org/reports/FBgn0266885 non_protein_coding_gene - - - CR45346 - CR45346 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266642 CR45149 - http://flybase.org/reports/FBgn0266642 non_protein_coding_gene - - - CR45149 - CR45149 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067363 l(2)NC45 lethal (2) NC45 http://flybase.org/reports/FBgn0067363 gene - - - l(2)NC45 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065227 l(2)SH2207 lethal (2) SH2207 http://flybase.org/reports/FBgn0065227 gene - - - l(2)SH2207 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029990 CG2233 - http://flybase.org/reports/FBgn0029990 protein_coding_gene - - - CG2233 - CG2233 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0003516 Stumpy Stumpy http://flybase.org/reports/FBgn0003516 - gene - - - "Stumpy, St" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male" "wing,abdomen,eye,macrochaeta" FBgn0022175 l(2)k05419a lethal (2) k05419a http://flybase.org/reports/FBgn0022175 - gene - - - "l(2)k05419, l(2)k05419a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013514 l(1)14Af lethal (1) 14Af http://flybase.org/reports/FBgn0013514 - gene - - - "XIII, l(1)XIII, l(1)13Fi, l(1)14Af" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265637 CR44444 - http://flybase.org/reports/FBgn0265637 non_protein_coding_gene - - - "CR44444, lincRNA.262, R5_2R:3508670..3509919" - CR44444 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032856 CG16798 - http://flybase.org/reports/FBgn0032856 protein_coding_gene - - - "38C.41, CG16798" - CG16798 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0052564 CG32564 - http://flybase.org/reports/FBgn0052564 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with MGI:MGI:1201690 dendrite morphogenesis ; GO:0048813 | inferred from sequence or structural similarity with HGNC:6868 microtubule ; GO:0005874 | inferred from sequence or structural similarity with HGNC:6868 "CG5095, CG32564" - CG32564 11-Aug-17 DroID_v2017_08 Drer\pou2af1 - - - "Mmus\Kprp, Mmus\Pou2af1, Mmus\2310050C09Rik" "Hsap\POU2AF1, Hsap\C1orf68" FBgn0013579 l(3)82Fg lethal (3) 82Fg http://flybase.org/reports/FBgn0013579 - gene - - - l(3)82Fg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0000328 clv-2 cloven thorax 2 http://flybase.org/reports/FBgn0000328 - gene - - - "Clv, clv-2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,visible,partially lethal - majority die,dominant" "adult thorax,wing,dorsal" FBgn0014296 l(3)64Bg lethal (3) 64Bg http://flybase.org/reports/FBgn0014296 - gene - - - l(3)64Bg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038463 CG3534 - http://flybase.org/reports/FBgn0038463 protein_coding_gene xylulokinase activity ; GO:0004856 | inferred from biological aspect of ancestor with PANTHER:PTN000023215 xylulokinase activity ; GO:0004856 | inferred from sequence or structural similarity with HGNC:12839 xylulose metabolic process ; GO:0005997 | inferred from sequence or structural similarity with HGNC:12839 xylulose metabolic process ; GO:0005997 | inferred from biological aspect of ancestor with PANTHER:PTN000023215 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:12839 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000023213 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:12839 CG3534 "IPR018484:Carbohydrate kinase, FGGY, N-terminal, IPR018485:Carbohydrate kinase, FGGY, C-terminal" CG3534 11-Aug-17 DroID_v2017_08 Drer\xylb Scer\XKS1 Cele\R08D7.7 Xtro\xylb Mmus\Xylb Hsap\XYLB viable FBgn0259708 CG42362 - http://flybase.org/reports/FBgn0259708 protein_coding_gene - - - "CG15675, CG42362" - CG42362 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042150 CG18827 - http://flybase.org/reports/FBgn0042150 protein_coding_gene - - - CG18827 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083010 snoRNA:Psi28S-1135c snoRNA:Psi28S-1135c http://flybase.org/reports/FBgn0083010 snoRNA_gene - - - "snoRNA:Psi28S-1135c, Psi28S-1135c, psi28S-1135c, CR34604" - CR34604 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014464 Cp7Fa Chorion protein a at 7F http://flybase.org/reports/FBgn0014464 "FBgn0030042, FBgn0030043, FBgn0053962, FBtr0071199, FBpp0071146, FBtr0071200, FBpp0071147" protein_coding_gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern inferred from genomic context chorion ; GO:0042600 | inferred by curator from GO:0007304 inferred from genomic context "Cp7Fa, CG33962, A, CG15349, CG15348" - CG33962 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage && oogenesis stage | stage S10B-13 , oogenesis stage | stage S12-13 " follicle cell

"visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0067090 I10 I10 http://flybase.org/reports/FBgn0067090 gene - - - I10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective,lethal,viable" "eye,pigment cell" FBgn0037940 CG14720 - http://flybase.org/reports/FBgn0037940 protein_coding_gene - - - CG14720 IPR006631:Protein of unknown function DM4/12 CG14720 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037797 CG12420 - http://flybase.org/reports/FBgn0037797 protein_coding_gene - - - CG12420 - CG12420 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0262851 CR43215 - http://flybase.org/reports/FBgn0262851 pseudogene_attribute - - - "CR43215, noncoding_23159, noncoding_23161" - CR43215 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028145 l(3)S045608 lethal (3) S045608 http://flybase.org/reports/FBgn0028145 gene - - - "0456/08, l(3)S045608" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0052448 CG32448 - http://flybase.org/reports/FBgn0052448 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32448 IPR026686:UPF0708 protein C6orf162 CG32448 11-Aug-17 DroID_v2017_08 Drer\smim8 - - Xtro\smim8 Mmus\Smim8 Hsap\SMIM8 "viable,fertile" DRSC22657 I 2.542714952 -0.263531391 1.199729296 0.103431017 0.083664237 0.023627844 FBgn0005065 fs(2)OW205 female sterile (2) OW205 http://flybase.org/reports/FBgn0005065 - gene - - - fs(2)OW205 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085209 CG34180 - http://flybase.org/reports/FBgn0085209 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34180 - CG34180 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033980 Cyp6a20 Cyp6a20 http://flybase.org/reports/FBgn0033980 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype aggressive behavior ; GO:0002118 | inferred from mutant phenotype" - "Cyp6a20, 6a20, CG10245, p450, CYP6a20" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10245 11-Aug-17 DroID_v2017_08 "Drer\cyp3c1, Drer\tbxas1, Drer\cyp3a65, Drer\cyp3c3, Drer\cyp3c2, Drer\cyp3c4" Scer\ERG11 "Cele\cyp-44A1, Cele\cyp-13B1, Cele\cyp-13B2, Cele\cyp-13A10, Cele\cyp-25A6, Cele\cyp-13A3, Cele\cyp-13A8, Cele\cyp-43A1, Cele\cyp-13A4, Cele\cyp-25A4, Cele\cyp-13A11, Cele\cyp-13A7, Cele\cyp-13A5, Cele\cyp-13A6, Cele\cyp-25A2, Cele\cyp-25A1, Cele\cyp-25A3, Cele\cyp-13A1, Cele\cyp-13A2, Cele\cyp-13A12" "Xtro\LOC100494419, Xtro\cyp3a5, Xtro\cyp3a4, Xtro\tbxas1" "Mmus\Tbxas1, Mmus\Cyp3a57, Mmus\Cyp3a59, Mmus\Cyp3a41a, Mmus\Cyp3a25, Mmus\Cyp3a16, Mmus\Cyp3a13, Mmus\Cyp3a41b, Mmus\Cyp3a11, Mmus\Cyp3a44" "Hsap\CYP3A7, Hsap\CYP3A5, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A4, Hsap\TBXAS1, Hsap\CYP3A43" viable FBgn0261680 CG42727 - http://flybase.org/reports/FBgn0261680 protein_coding_gene - - - "CG12258, CG31392, CG42727" - CG42727 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026306 anon-16Fc anon-16Fc http://flybase.org/reports/FBgn0026306 - gene - - - "HL-IV, anon-16Fc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052087 CG32087 - http://flybase.org/reports/FBgn0052087 protein_coding_gene molecular_function ; GO:0003674 | no biological data available exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 regulation of autophagy ; GO:0010506 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 single organismal cell-cell adhesion ; GO:0016337 | inferred from sequence or structural similarity with HGNC:29559 endoplasmic reticulum organization ; GO:0007029 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN000031590 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:29559 "CG7308, CG32087" - CG32087 11-Aug-17 DroID_v2017_08 Drer\vmp1 - Cele\epg-3 Xtro\vmp1 Mmus\Vmp1 Hsap\VMP1 viable FBgn0004188 snRNA:U6:96Aa small nuclear RNA U6 at 96Aa http://flybase.org/reports/FBgn0004188 "FBgn0003455, FBgn0003939, FBgn0003940, FBgn0051379" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U6 snRNP ; GO:0005688 | inferred from sequence or structural similarity "snRNA:U6:96Aa, CR31379, U6, U6-96Aa, snRNA-b, U6-1, U6snRNA, U6 RNA, DU6-1, snRNA[[4]], K1, dU6, snRNA:U6, snRNA6, snRNA4, U6snRNA96Aa, U6:96Aa, U6 snRNA, U6-snRNA" - CR31379 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063920 M(UAS-dsh)8-4 M(UAS-dsh)8-4 http://flybase.org/reports/FBgn0063920 gene molecular_function ; GO:0003674 | no biological data available Wnt signaling pathway ; GO:0016055 | inferred from genetic interaction with dsh cellular_component ; GO:0005575 | no biological data available "UAS-dsh M[8-4], M(UAS-dsh)8-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020292 l(2)39DEp lethal (2) 39DEp http://flybase.org/reports/FBgn0020292 - gene - - - "I259, l(2)39DEp" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014250 l(2)60Ac lethal (2) 60Ac http://flybase.org/reports/FBgn0014250 - gene - - - l(2)60Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0016050 obx obelix http://flybase.org/reports/FBgn0016050 - gene molecular_function ; GO:0003674 | no biological data available peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available obx - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,some die during immature adult stage" "presumptive embryonic/larval peripheral nervous system,neuron,fascicle" FBgn0060400 l(3)S131909b lethal (3) S131909b http://flybase.org/reports/FBgn0060400 gene - - - "1319/09, l(3)S131909b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025608 Faf2 Fas-associated factor http://flybase.org/reports/FBgn0025608 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "GT#49, FFAF, CG10372, Faf2, Faf" "IPR001012:UBX domain, IPR006577:UAS, IPR012336:Thioredoxin-like fold, IPR029071:Ubiquitin-related domain" CG10372 11-Aug-17 DroID_v2017_08 "Drer\faf2, Drer\faf1, Drer\ubxn8" "Scer\UBX2, Scer\UBX3" "Cele\ubxn-3, Cele\H40L08.1, Cele\ubc-23" Xtro\faf2 "Mmus\Faf1, Mmus\Faf2, Mmus\Ubxn8" "Hsap\UBXN8, Hsap\FAF1, Hsap\FAF2" "viable,fertile" FBgn0032972 CG10834 - http://flybase.org/reports/FBgn0032972 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506" microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR016561 dynein complex ; GO:0030286 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 CG10834 "IPR004942:Roadblock/LAMTOR2 domain, IPR016561:Dynein light chain roadblock-type 1/2" CG10834 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-147k9.8, Drer\dynlrb1" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb1, Mmus\Dynlrb2" "Hsap\DYNLRB1, Hsap\DYNLRB2" FBgn0013239 E(var)211 E(var)211 http://flybase.org/reports/FBgn0013239 - gene - - - E(var)211 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0044059 GTD74-295-1 GTD74-295-1 http://flybase.org/reports/FBgn0044059 gene - - - GTD74-295-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036951 CG7017 - http://flybase.org/reports/FBgn0036951 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG7017 IPR002557:Chitin binding domain CG7017 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\C39D10.7, Cele\R02F2.4" - - Hsap\MATN2 viable FBgn0033726 Cpr49Ad Cuticular protein 49Ad http://flybase.org/reports/FBgn0033726 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr49Ad, CG8836" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8836 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\F44F1.4, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - FBgn0037409 Osi24 Osiris 24 http://flybase.org/reports/FBgn0037409 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15589, Osi24" IPR012464:Protein of unknown function DUF1676 CG15589 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001014 fs(3)A5 female sterile (3) A5 http://flybase.org/reports/FBgn0001014 - gene - - - fs(3)A5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0265708 CR44515 - http://flybase.org/reports/FBgn0265708 non_protein_coding_gene - - - "incRNA.440, CR44515, lincRNA.440" - CR44515 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028601 l(2)W6 lethal (2) W6 http://flybase.org/reports/FBgn0028601 gene - - - "l(2R)W6, l(2)W6" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034982 Naa35 N(alpha)-acetyltransferase 35 http://flybase.org/reports/FBgn0034982 protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from biological aspect of ancestor with PANTHER:PTN000483166 N-terminal protein amino acid acetylation ; GO:0006474 | inferred from biological aspect of ancestor with PANTHER:PTN000483166 NatC complex ; GO:0031417 | inferred from biological aspect of ancestor with PANTHER:PTN000483166 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q6PHQ8 "anon-EST:Nelson1, Naa35, CG4065" "IPR007244:NatC N(alpha)-terminal acetyltransferase, Mak10 subunit" CG4065 11-Aug-17 DroID_v2017_08 Drer\naa35 Scer\MAK10 Cele\natc-1 Xtro\naa35 Mmus\Naa35 Hsap\NAA35 viable FBgn0034877 levy levy http://flybase.org/reports/FBgn0034877 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from mutant phenotype enzyme regulator activity ; GO:0030234 | inferred from mutant phenotype cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProt:Q02221 inferred from sequence or structural similarity with UniProtKB:P12074 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from mutant phenotype regulation of catalytic activity ; GO:0050790 | inferred from mutant phenotype mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProt:Q02221 inferred from sequence or structural similarity with UniProtKB:P12074 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000161400 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" lipid particle ; GO:0005811 | inferred from direct assay mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000161401 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred by curator from GO:0004129 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProt:Q02221 inferred from sequence or structural similarity with UniProtKB:P12074 "VIa, BcDNA:RH03295, levy, CG17280, COX6A, COXD, COXE, Cox6a" "IPR001349:Cytochrome c oxidase, subunit VIa" CG17280 11-Aug-17 DroID_v2017_08 "Drer\cox6a1, Drer\cox6a2" Scer\COX13 Cele\tag-174 "Xtro\cox6a1, Xtro\cox6a2" "Mmus\Cox6a1, Mmus\Cox6a2" "Hsap\COX6A2, Hsap\COX6A1" "viable,paralytic,heat sensitive,short lived,bang sensitive,neuroanatomy defective" "adult brain,optic lobe" DRSC04289 E -0.683115008 -0.259176279 -1.584119705 -0.38076981 -0.025054032 -0.439776477 FBgn0061133 l(3)S001917 lethal (3) S001917 http://flybase.org/reports/FBgn0061133 gene - - - "0019/17, l(3)S001917" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0030440 CG15719 - http://flybase.org/reports/FBgn0030440 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR005772 ATPase coupled ion transmembrane transporter activity ; GO:0042625 | inferred from biological aspect of ancestor with PANTHER:PTN001015339" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR005772 "proton-transporting V-type ATPase, V1 domain ; GO:0033180 | inferred from electronic annotation with InterPro:IPR005772 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001015339" CG15719 "IPR005772:ATPase, V1 complex, subunit F, eukaryotic, IPR008218:ATPase, V1 complex, subunit F" CG15719 11-Aug-17 DroID_v2017_08 Drer\atp6v1f Scer\VMA7 Cele\vha-9 - Mmus\Atp6v1f Hsap\ATP6V1F FBgn0262806 CR43177 - http://flybase.org/reports/FBgn0262806 pseudogene_attribute - - - "CG43177, CR43177" - CR43177 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000348 cop copper http://flybase.org/reports/FBgn0000348 - gene - - - cop - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,recessive,visible,viable,fertile" "pigment cell,wing" FBgn0265271 CG14717 - http://flybase.org/reports/FBgn0265271 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from sequence or structural similarity with CG2059 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14717, anon-SAGE:Wang-126" "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG14717 11-Aug-17 DroID_v2017_08 "Drer\abhd11, Drer\derl1, Drer\abhd4, Drer\abhd8b" "Scer\ECM18, Scer\YGR015C, Scer\ICT1, Scer\CLD1, Scer\IMO32" "Cele\abhd-11.2, Cele\abhd-5.2, Cele\C31H5.1, Cele\abhd-5.1, Cele\abhd-11.1, Cele\B0464.9, Cele\F35H12.5" "Xtro\derl1, Xtro\abhd8, Xtro\abhd11" "Mmus\Abhd8, Mmus\Abhd11, Mmus\Derl1, Mmus\Abhd4" "Hsap\ABHD4, Hsap\DERL1, Hsap\ABHD11" FBgn0035099 CG6845 - http://flybase.org/reports/FBgn0035099 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012858 "BEST:LD22345, CG6845" IPR012858:Dendritic cell-specific transmembrane protein-like CG6845 11-Aug-17 DroID_v2017_08 "Drer\dcst2, Drer\dcst1" - "Cele\K12B6.2, Cele\spe-42, Cele\npp-22, Cele\srh-97" "Xtro\LOC100497585, Xtro\LOC101734522" "Mmus\Dcstamp, Mmus\Dcst2, Mmus\Dcst1, Mmus\Ocstamp" "Hsap\OCSTAMP, Hsap\DCSTAMP, Hsap\DCST1, Hsap\DCST2" FBgn0011050 l(1)Q3 lethal (1) Q3 http://flybase.org/reports/FBgn0011050 FBgn0010210 gene - - - l(1)Q3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000546 EcR Ecdysone receptor http://flybase.org/reports/FBgn0000546 "FBgn0011242, FBgn0021762, FBgn0033064, FBgn0062534" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with usp DNA binding ; GO:0003677 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Utx RNA polymerase II transcription coactivator binding ; GO:0001225 | inferred from physical interaction with crc ecdysteroid hormone receptor activity ; GO:0004884 | contributes_to inferred from physical interaction with usp transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay ecdysone binding ; GO:0035100 | inferred from direct assay RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with rig steroid binding ; GO:0005496 | non-traceable author statement ecdysteroid hormone receptor activity ; GO:0004884 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | inferred from sequence or structural similarity with MGI:MGI:1352464 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with usp repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with alien RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay core promoter binding ; GO:0001047 | inferred from direct assay" "cholesterol homeostasis=0042632 |...<> pupariation=0035073 |...<> oogenesis=0048477 | <> epidermis development=0008544 |...<> mushroom body development=0016319 |...<> ecdysone receptor-mediated signaling pathway=0035076 |...<> regulation of cellular respiration=0043457 |...<> neuron remodeling=0016322 |...<> sperm individualization=0007291 |...<> muscle organ development=0007517 |...<> positive regulation of circadian sleep/wake cycle, sleep=0045938 |...<> regulation of glucose metabolic process=0010906 |...<> mushroom body development=0016319 |... genetic interaction with babo inferred from genetic interaction with Smox <> border follicle cell migration=0007298 |...<> imaginal disc-derived wing morphogenesis=0007476 |...inferred from genetic interaction with if inferred from genetic interaction with mys <> larval central nervous system remodeling=0035193 |...<> oogenesis=0048477 |...<> metamorphosis=0007552 |...<> larval central nervous system remodeling=0035193 | traceable author statement <> regulation of hemocyte proliferation=0035206 |...<> phagocytosis, engulfment=0006911 |...<> germ-band shortening=0007390 |...<> peripheral nervous system development=0007422 |...<> regulation of neuron remodeling=1904799 |...<> ecdysone-mediated induction of salivary gland cell autophagic cell death=0035072 | <> negative regulation of growth of symbiont in host=0044130 |...<> negative regulation of neuroblast proliferation=0007406 |...<> regulation of Malpighian tubule diameter=0035297 |...<> response to cocaine=0042220 |... genetic interaction with InR <> hatching=0035188 |...<> dendrite morphogenesis=0048813 | <> regulation of development, heterochronic=0040034 | traceable author statement <> germ cell development=0007281 |...<> spermatid development=0007286 |...<> positive regulation of transcription from RNA polymerase II promoter=0045944 |...<> cardioblast differentiation=0010002 |...<> regulation of autophagy=0010506 |...<> positive regulation of apoptotic process=0043065 |...<> ecdysis, chitin-based cuticle=0018990 |...<> cardiac muscle tissue development=0048738 |...<> positive regulation of transcription from RNA polymerase II promoter=0045944 |... genetic interaction with Sgs4 <> regulation of transcription from RNA polymerase II promoter=0006357 |...<> negative regulation of transcription, DNA-templated=0045892 | traceable author statement <> chitin-based embryonic cuticle biosynthetic process=0008362 |...<> Malpighian tubule morphogenesis=0007443 |...<> response to ecdysone=0035075 |...<> determination of adult lifespan=0008340 |...<> positive regulation of transcription, DNA-templated=0045893 |...<> head involution=0008258 |...<> long-term memory=0007616 |...<> cell adhesion=0007155 |...<> regulation of rhodopsin gene expression=0007468 |...<> dendrite morphogenesis=0048813 |...<> larval wandering behavior=0035180 |...<> autophagy=0006914 |...<> neuron development=0048666 |...<> dorsal vessel heart proper cell fate commitment=0035053 |...<> salivary gland cell autophagic cell death=0035071 |...<> histoblast morphogenesis=0007488 |...<> imaginal disc eversion=0007561 | traceable author statement" polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay ecdysone receptor holocomplex ; GO:0008230 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay repressor ecdysone receptor complex ; GO:0008231 | inferred from physical interaction with alien polytene chromosome ; GO:0005700 | non-traceable author statement activator ecdysone receptor complex ; GO:0008232 | inferred from direct assay dendrite ; GO:0030425 | inferred from mutant phenotype ecdysone receptor holocomplex ; GO:0008230 | inferred from physical interaction with usp "DmEcR, EcR, Ecr, EcRB1, EcR-B1, ecr, EcRB-1, CG1765, EcR-A, NR1H1, DEcR, snt, ECR, dECR, lie, EcdR, CG8347, ms(2)42A, ms(2)06410, Dhr23, anon-WO0229075.1, EcR-B, ECR-C, dmEcR, Ecr1B, EcR1b, EcRA, EcRC, EcRB" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR003069:Ecdysteroid receptor, IPR013088:Zinc finger, NHR/GATA-type" CG1765 11-Aug-17 DroID_v2017_08 "Drer\rxrba, Drer\rarab, Drer\nr2f1b, Drer\nr2c1, Drer\nr1i2, Drer\nr2f5, Drer\nr0b2b, Drer\esrra, Drer\rxrab, Drer\vdra, Drer\nr0b2a, Drer\nr2e3, Drer\nr3c1, Drer\pparda, Drer\nr2f1a, Drer\pparaa, Drer\ar, Drer\pparg, Drer\raraa, Drer\pgr, Drer\nr1h3, Drer\nr2e1, Drer\vdrb, Drer\nr2f6b, Drer\nr0b1, Drer\esrrga, Drer\rxrbb, Drer\nr1h4, Drer\nr2f6a, Drer\esrrd, Drer\esr1, Drer\nr1h5, Drer\rxrga, Drer\nr5a1a, Drer\rargb, Drer\nr2f2, Drer\esr2b, Drer\nr2c2, Drer\rxraa, Drer\ppardb, Drer\nr6a1b, Drer\esr2a, Drer\pparab, Drer\thrab" - "Cele\nhr-87, Cele\daf-12, Cele\nhr-199, Cele\nhr-44, Cele\nhr-53, Cele\nhr-105, Cele\nhr-219, Cele\nhr-134, Cele\nhr-178, Cele\nhr-112, Cele\nhr-84, Cele\nhr-8, Cele\nhr-237, Cele\nhr-132, Cele\nhr-213, Cele\nhr-57, Cele\nhr-181, Cele\nhr-238, Cele\nhr-43, Cele\nhr-182, Cele\nhr-6, Cele\nhr-234" "Xtro\esrrg, Xtro\ar, Xtro\nr2f2, Xtro\nr3c2, Xtro\thrb, Xtro\esrrb, Xtro\nr6a1, Xtro\rara, Xtro\pgr, Xtro\rarg, Xtro\nr1i2, Xtro\nr2f5, Xtro\esrrgr, Xtro\rxrb, Xtro\esrra, Xtro\esr1, Xtro\nr1h2, Xtro\nr0b2, Xtro\nr2c2, Xtro\nr0b1, Xtro\nr3c1, Xtro\nr2e1, Xtro\rxra, Xtro\vdr, Xtro\nr2f6, Xtro\nr2c1, Xtro\esr2, Xtro\ppard, Xtro\pparg, Xtro\ppara, Xtro\nr2f1, Xtro\nr1h5, Xtro\nr2e3, Xtro\rxrg, Xtro\rarb" "Mmus\Rxrg, Mmus\Nr1i2, Mmus\Nr2e1, Mmus\Pparg, Mmus\Ppard, Mmus\Nr1h5, Mmus\Nr1i3, Mmus\Rarb, Mmus\Esr1, Mmus\Nr6a1, Mmus\Esr2, Mmus\Esrra, Mmus\Nr3c2, Mmus\Rara, Mmus\Thra, Mmus\Rxra, Mmus\Nr1h3, Mmus\Rarg, Mmus\Pgr, Mmus\Nr2f2, Mmus\Rxrb, Mmus\Thrb, Mmus\Nr2e3, Mmus\Nr1h2, Mmus\Nr0b2, Mmus\Nr2c1, Mmus\Nr3c1, Mmus\Nr2c2, Mmus\Nr2f6, Mmus\Ar, Mmus\Nr1h4, Mmus\Esrrb, Mmus\Vdr, Mmus\Nr0b1, Mmus\Esrrg, Mmus\Ppara, Mmus\Nr2f1" "Hsap\NR1H3, Hsap\PPARA, Hsap\RXRA, Hsap\PGR, Hsap\AR, Hsap\NR6A1, Hsap\RARG, Hsap\ESRRA, Hsap\NR2F6, Hsap\RARA, Hsap\NR0B2, Hsap\RXRG, Hsap\NR2C2, Hsap\ESRRB, Hsap\NR2E1, Hsap\RARB, Hsap\RXRB, Hsap\NR1H2, Hsap\THRB, Hsap\NR0B1, Hsap\NR1I2, Hsap\ESR2, Hsap\NR3C2, Hsap\PPARG, Hsap\NR2F1, Hsap\NR3C1, Hsap\NR2F2, Hsap\NR1I3, Hsap\PPARD, Hsap\ESR1, Hsap\NR2C1, Hsap\THRA, Hsap\VDR, Hsap\NR1H4, Hsap\ESRRG" " embryonic stage | late , larval stage | second instar , pupal stage | early , larval stage--adult stage , pupal stage | mid , embryonic stage | mid , embryonic stage | >=3 hr , larval stage | first instar , pupal stage , larval stage | late third instar larval stage , larval stage | third instar , embryonic stage | 0-3 hr " organism

" prepupal stage , adult stage && oogenesis stage , larval stage | first instar , larval stage | late third instar larval stage , pupal stage | >=12 hr , pupal stage , embryonic stage , adult stage , embryonic stage | early " " ventral thoracic disc

, follicle cell

, epidermis

, eye-antennal disc

, embryonic/larval trachea

, imaginal disc

, embryonic/larval midgut

, organism

, neuron | subset

, salivary gland imaginal ring

, histoblast nest

, foregut imaginal ring

, nurse cell

, ovary

, hindgut imaginal ring

, prothoracic gland

, Malpighian tubule

, ventral nervous system | restricted

, larval muscle system

, midgut imaginal island

, embryonic/larval salivary gland

, dorsal metathoracic disc

, labial disc

, embryonic/larval fat body

" "lethal,recessive,heat sensitive,sleep defective,dominant,long lived,male,RU486 conditional,short lived,female,neuroanatomy defective,visible,size defective,male sterile,partially lethal - majority die,partially,cell death defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,feeding behavior defective,locomotor behavior defective,female sterile,some die during pupal stage,some die during third instar larval stage,courtship behavior defective,conditional,memory defective,decreased cell death,mitotic cell cycle defective,lethal - all die before end of P-stage,some die during pharate adult stage,male fertile,lethal - all die before end of pupal stage,viable,lethal - all die before end of first instar larval stage,some die during first instar larval stage,small body,developmental rate defective,cell shape defective,decreased cell size,circadian rhythm defective" "germline cell,supernumerary,heat sensitive,female germline cell,somatic clone,photoreceptor,lobe system of adult mushroom body,mushroom body beta-lobe,eye,mushroom body gamma-lobe | adult stage,adult mushroom body,spermatid,spermatozoon,primary spermatocyte cyst,spermatid & nucleus,wing,wing vein,ectopic,wing vein L3,anterior crossvein,leg,fusome | heat sensitive,cephalopharyngeal skeleton,embryonic/larval cuticle,embryonic/larval posterior spiracle,ventral thoracic disc,gastric caecum,embryonic/larval salivary gland | embryonic stage,midgut imaginal island,pupa,embryonic/larval midgut,adult midgut,salivary gland,germ band,puparium,puparial operculum,head,mouth hooks,egg chamber,germline clone,stage S14 oocyte,follicle cell,midgut constriction,embryo,embryonic/larval tracheal system,pupal cuticle,anterior pupal spiracle,embryonic/larval salivary gland,nurse cell ring canal,neuron & ventral nerve cord,gamma-lobe & neuron,adult brain,larva,nurse cell & nucleus | conditional ts,tergite,peripodial epithelium,histoblast nest,embryonic head,labral segment,epipharyngeal sclerite,dorsal pouch,Tv neuron & axonFMRFa.PS,neurohemal organ,ommatidium,pigment cell,wing disc,synapseMhc.PW,mesothoracic ventral neurosecretory neuron & axonFMRFa.PS,metathoracic ventral thoracic neurosecretory neuron & axonFMRFa.PS,prothoracic ventral neurosecretory neuron & axonFMRFa.PS,motor neuron,prepupal cuticle,germarium cap cell,border follicle cell,dorsal appendage,egg operculum,chorion,maternal effect,posterior scutellar bristle,imaginal disc,polytene chromosome puffSgs3.PD,embryonic/larval salivary gland | third instar larval stage,embryonic/larval salivary gland | prepupal stage,embryonic/larval salivary gland | pupal stage,autophagic vacuoleLsp2.PH,embryonic/larval fat body,mushroom body | P-stage,glial cell & brain & pupa | conditional tsTab2-201Y,dorsal closure embryo,extended germ band embryo,embryonic/first instar larval cuticle,neuron & ventral nerve cordCrz.PC,embryonic/larval epidermis,pupal epidermis,dendritic arborizing neuron | P-stage,embryonic/larval Malpighian tubule | larval stage,embryonic/larval Malpighian tubule Type II cell,wing margin,wing hair,embryonic/larval neuromuscular junction | larval stage,transverse nerve,reticular neuropil associated glial cell,gamma Kenyon cell,synapsealrm.PD,lysosomeLsp2.PH,fat body,autolysosomeLsp2.PH,microtubule & dorsal multidendritic neuron ddaC | pupal stageppk.PG,dendrite109(2)80,dorsal multidendritic neuron ddaC,oocyte,neuroblast,larval neuromere,CSD interneuron,midgut,denticle belt,embryo | dorsal closure stage,embryo | embryonic stage 14,amnioserosa,polar follicle cell,Tv neuron & filopodiumFMRFa.PS" FBgn0038440 Gr89a Gustatory receptor 89a http://flybase.org/reports/FBgn0038440 protein_coding_gene taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity with Gr5a detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from sequence or structural similarity with Gr5a integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | inferred from sequence model "CG14901, Gr89a, GR89a" IPR013604:7TM chemoreceptor CG14901 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0265157 CR44226 - http://flybase.org/reports/FBgn0265157 non_protein_coding_gene - - - "CR44226, lincRNA.835" - CR44226 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053825 His1:CG33825 His1:CG33825 http://flybase.org/reports/FBgn0053825 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33825, His1:CG33825" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33825 11-Aug-17 DroID_v2017_08 "Drer\zgc:163061, Drer\h1m, Drer\zgc:153405, Drer\histh1l, Drer\zgc:110216, Drer\zgc:110425, Drer\si:dkey-108k21.14, Drer\h1fx, Drer\si:dkey-108k21.10, Drer\si:ch211-113a14.24, Drer\si:dkey-261m9.12, Drer\si:ch73-36p18.1, Drer\si:dkey-108k21.21, Drer\h1f0, Drer\si:ch1073-159d7.7" Scer\HHO1 "Cele\hil-3, Cele\hil-6, Cele\hil-5, Cele\hil-2, Cele\hil-4, Cele\hil-1, Cele\his-24" Xtro\h1f0 "Mmus\Hist1h1a, Mmus\Hist1h1c, Mmus\H1foo, Mmus\Hist1h1t, Mmus\Hist1h1e, Mmus\H1fnt, Mmus\Hist1h1b, Mmus\H1fx, Mmus\Hist1h1d, Mmus\H1f0, Mmus\Hils1" "Hsap\HIST1H1T, Hsap\H1FNT, Hsap\HIST1H1D, Hsap\HIST1H1E, Hsap\HIST1H1A, Hsap\HIST1H1C, Hsap\H1F0, Hsap\H1FX, Hsap\H1FOO, Hsap\HIST1H1B" FBgn0001825 l(1)ts lethal (1) ts http://flybase.org/reports/FBgn0001825 - gene - - - l(1)ts - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cold sensitive" FBgn0029751 CG17764 - http://flybase.org/reports/FBgn0029751 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000914" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000000914 CG17764 - CG17764 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002805 ms(1)19Fd male sterile (1) 19Fd http://flybase.org/reports/FBgn0002805 - gene - - - ms(1)19Fd - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0005435 l(1)v25 lethal (1) v25 http://flybase.org/reports/FBgn0005435 - gene - - - "l(1)25, l(1)v25" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025549 unc-119 unc-119 http://flybase.org/reports/FBgn0025549 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available lipoprotein transport ; GO:0042953 | inferred from biological aspect of ancestor with PANTHER:PTN000310586 neuron differentiation ; GO:0030182 | inferred from biological aspect of ancestor with PANTHER:PTN000310587 nervous system development ; GO:0007399 | inferred from genetic interaction with WB:WBGene00006843 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000310586 "dm unc-119, Unc-119, anon-EST:Posey123, CG1659, unc-119, Unc119, DmUNC-119" "IPR008015:GMP phosphodiesterase, delta subunit, IPR014756:Immunoglobulin E-set" CG1659 11-Aug-17 DroID_v2017_08 "Drer\unc119.1, Drer\unc119a, Drer\unc119b, Drer\unc119.2, Drer\mlec" - "Cele\unc-119, Cele\F44E2.10" "Xtro\unc119b, Xtro\unc119, Xtro\mlec" "Mmus\Unc119, Mmus\Mlec, Mmus\Unc119b" "Hsap\MLEC, Hsap\UNC119, Hsap\UNC119B" viable FBgn0028837 CSN6 COP9 signalosome subunit 6 http://flybase.org/reports/FBgn0028837 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from direct assay zinc ion binding ; GO:0008270 | NOT inferred from direct assay NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype metallopeptidase activity ; GO:0008237 | NOT inferred from key residues female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs germ cell development ; GO:0007281 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from sequence or structural similarity with HGNC:21749 COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity with MGI:MGI:1349439 COP9 signalosome ; GO:0008180 | inferred from direct assay COP9 signalosome ; GO:0008180 | inferred from mutant phenotype "CSN6, Dch6, CH6, CG6932, Csn6, Q9VCY3" "IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR024969:Rpn11/EIF3F, C-terminal, IPR033859:COP9 signalosome subunit 6" CG6932 11-Aug-17 DroID_v2017_08 Drer\cops6 Scer\RPN8 Cele\csn-6 Xtro\cops6 Mmus\Cops6 Hsap\COPS6 "lethal,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,locomotor behavior defective,short lived" "embryonic/larval brain,chaeta,supernumerary,trichogen cell,mesothoracic tergum,scutellar bristle" DRSC16593 K -0.011801496 -0.535545111 0.164144701 1.168583481 3.257681893 2.858732957 FBgn0033527 CG11777 - http://flybase.org/reports/FBgn0033527 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:9261" catalytic step 2 spliceosome ; GO:0071013 | inferred from sequence or structural similarity with HGNC:9262 "BcDNA:RE61564, CG11777, cg11777" "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain" CG11777 11-Aug-17 DroID_v2017_08 "Drer\pxnb, Drer\ppil3, Drer\si:rp71-15d4.1, Drer\pxna" "Scer\CPR2, Scer\CPR5" "Cele\cyn-10, Cele\cyn-4, Cele\pxl-1" "Xtro\ppil3, Xtro\tgfb1i1, Xtro\ppil2, Xtro\pxn" "Mmus\Lpxn, Mmus\Ppil3, Mmus\Ppil2, Mmus\Tgfb1i1, Mmus\Pxn" "Hsap\PPIL3, Hsap\LPXN, Hsap\PPIL2, Hsap\PXN, Hsap\TGFB1I1" FBgn0015399 kek1 kekkon-1 http://flybase.org/reports/FBgn0015399 "FBgn0005766, FBgn0028957" protein_coding_gene receptor antagonist activity ; GO:0048019 | inferred from direct assay epidermal growth factor receptor binding ; GO:0005154 | inferred from physical interaction with Egfr negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype inferred from genetic interaction with grk inferred from genetic interaction with Egfr negative regulation of epidermal growth factor-activated receptor activity ; GO:0007175 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype inferred from genetic interaction with Egfr mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | traceable author statement negative regulation of epidermal growth factor-activated receptor activity ; GO:0007175 | traceable author statement integral component of membrane ; GO:0016021 | traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from sequence model "kek-1, Dmkek1, SD01674, kekon, Kek, Kek-1, KEK1, kek, Kek1, CT18186, NB1, uns, l(2)01433, GM02380, n(2)k07332, BEST:GM02380, CG12283, kek1" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR003598:Immunoglobulin subtype 2, IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR013098:Immunoglobulin I-set, IPR013783:Immunoglobulin-like fold, IPR003591:Leucine-rich repeat, typical subtype, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype" CG12283 11-Aug-17 DroID_v2017_08 "Drer\lrit2, Drer\lrfn5a, Drer\islr2, Drer\lrit1a, Drer\si:dkey-52j6.3, Drer\si:ch1073-303k11.2, Drer\lrit1b, Drer\LOC101882074, Drer\lrit3a, Drer\lrtm1, Drer\lrtm2a, Drer\lrit3b, Drer\lrtm2b, Drer\lrrc38a, Drer\lrrc38b, Drer\LOC564748, Drer\lrrc24" - Cele\iglr-3 "Xtro\amigo2, Xtro\lrit2, Xtro\lrrc52, Xtro\lrtm2, Xtro\lrit3, Xtro\islr2, Xtro\lrfn5, Xtro\lrrc24" "Mmus\Slitrk2, Mmus\Lrrc38, Mmus\Lrit1, Mmus\Lrtm1, Mmus\Lrrc52, Mmus\Lrit2, Mmus\Lrtm2, Mmus\Lrrc55, Mmus\Islr2, Mmus\Lrrc24, Mmus\Lrrn4, Mmus\Lrrn4cl, Mmus\Slitrk3, Mmus\Lrrc26, Mmus\Slitrk6, Mmus\Slitrk4, Mmus\Slitrk5, Mmus\Lrfn5, Mmus\Slitrk1, Mmus\Islr, Mmus\Lrit3" "Hsap\LRRN4CL, Hsap\LRRC52, Hsap\LRIT1, Hsap\LRTM1, Hsap\AMIGO1, Hsap\ISLR, Hsap\LRRC24, Hsap\LRIT2, Hsap\ISLR2, Hsap\LRRN4, Hsap\LRRC26, Hsap\AMIGO2, Hsap\LRTM2, Hsap\AMIGO3, Hsap\LRRC38, Hsap\LRRC55, Hsap\LRIT3" " adult stage | female , embryonic stage " " ovary

, antenno-maxillary complex

, central nervous system

, peripheral nervous system | restricted

" "visible,lethal,recessive,neuroanatomy defective,viable" "wing vein,ectopic,dorsal appendage,maternal effect,egg,chorion | dorsalCY2,eye,chorion,wing vein L4,embryo,photoreceptor cell,ommatidium,wing vein L5,posterior crossvein,border follicle cell,wing,embryonic/larval neuroblast,ganglion mother cell" FBgn0066125 E(sda)I E(sda)I http://flybase.org/reports/FBgn0066125 gene - - - "E(sda)I, Line I" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050072 Obp50c Odorant-binding protein 50c http://flybase.org/reports/FBgn0050072 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "CG30072, Obp50c, DmelObp50c" IPR006170:Pheromone/general odorant binding protein CG30072 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001523 l(1)11Db lethal (1) 11Db http://flybase.org/reports/FBgn0001523 - gene - - - l(1)11Db - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone" FBgn0043351 EP3390 EP3390 http://flybase.org/reports/FBgn0043351 gene - - - "EP(3)3390, EP3390" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016637 E64 E64 http://flybase.org/reports/FBgn0016637 - gene - - - E64 - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive" FBgn0023212 EloB Elongin B http://flybase.org/reports/FBgn0023212 FBgn0038807 protein_coding_gene - imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype inferred from genetic interaction with corto larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype elongin complex ; GO:0070449 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay VCB complex ; GO:0030891 | inferred from biological aspect of ancestor with PANTHER:PTN000997498 "Elongin-B, CG4204, EloB, Elo-B" "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG4204 11-Aug-17 DroID_v2017_08 "Drer\LOC569097, Drer\tceb2" - Cele\elb-1 Xtro\tceb2 Mmus\Elob Hsap\TCEB2 "lethal - all die before end of second instar larval stage,visible,dominant,lethal,viable,partially lethal - majority die" "wing vein L5,trichogen cell" FBgn0043999 Su(rst)C451 Su(rst)C451 http://flybase.org/reports/FBgn0043999 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C451, Su(rst)C451" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016783 anon-91Aa anon-91Aa http://flybase.org/reports/FBgn0016783 - gene - - - anon-91Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032488 CG16812 - http://flybase.org/reports/FBgn0032488 protein_coding_gene - - nucleus ; GO:0005634 | inferred from direct assay CG16812 "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG16812 11-Aug-17 DroID_v2017_08 Drer\si:ch211-160d20.3 - Cele\F53F8.5 Xtro\c19orf47 Mmus\2310022A10Rik Hsap\C19orf47 viable FBgn0051323 CG31323 - http://flybase.org/reports/FBgn0051323 protein_coding_gene - - - "CG14558, CG31323" - CG31323 11-Aug-17 DroID_v2017_08 - - Cele\C30G7.2 - - - "viable,fertile" FBgn0043859 pf-7 pairing failure-7 http://flybase.org/reports/FBgn0043859 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG7, pf-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030438 CG15721 - http://flybase.org/reports/FBgn0030438 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN001848130 chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern negative regulation of serine-type endopeptidase activity ; GO:1900004 | inferred from biological aspect of ancestor with PANTHER:PTN001848130 chorion ; GO:0042600 | inferred by curator from GO:0007304 CG15721 IPR002350:Kazal domain CG15721 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC19688 K -0.55107081 0.446321077 0.560768003 0.011024459 1.772834023 1.159722573 FBgn0028467 CG11070 - http://flybase.org/reports/FBgn0028467 protein_coding_gene ubiquitin-ubiquitin ligase activity ; GO:0034450 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 ubiquitin-ubiquitin ligase activity ; GO:0034450 | inferred from sequence or structural similarity with SGD:S000002349 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 ubiquitin ligase complex ; GO:0000151 | inferred from electronic annotation with InterPro:IPR019474 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000358161 "BcDNA:LD34475, CG11070, UBE4A, CG 11070, UFD2a, E4 A" "IPR003613:U box domain, IPR019474:Ubiquitin conjugation factor E4, core, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11070 11-Aug-17 DroID_v2017_08 "Drer\ube4a, Drer\ube4b, Drer\ubox5" Scer\UFD2 Cele\ufd-2 "Xtro\ubox5, Xtro\ube4a, Xtro\ube4b" "Mmus\Ubox5, Mmus\Ube4b, Mmus\Ube4a" "Hsap\UBOX5, Hsap\UBE4B, Hsap\UBE4A" viable FBgn0264868 CR44059 - http://flybase.org/reports/FBgn0264868 non_protein_coding_gene - - - "CR44059, lincRNA.34" - CR44059 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259415 EP-256 - http://flybase.org/reports/FBgn0259415 gene - - - EP-256 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,chaeta" FBgn0261396 Rpn3 Regulatory particle non-ATPase 3 http://flybase.org/reports/FBgn0261396 protein_coding_gene enzyme regulator activity ; GO:0030234 | inferred from electronic annotation with InterPro:IPR013586 zinc ion binding ; GO:0008270 | inferred from direct assay regulation of protein catabolic process ; GO:0042176 | inferred from electronic annotation with InterPro:IPR013586 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000079485 "proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000000823 proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000079540 proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9560 inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay" "p58, Dox-A2, CG10484, Rpn3, DoxA2, Dox, DXA2_DROME, l(2)37Bf, l(2)37Bf[+], CG42641, RPN3, S3" "IPR000717:Proteasome component (PCI) domain, IPR013586:26S proteasome regulatory subunit, C-terminal, IPR011990:Tetratricopeptide-like helical domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG42641 11-Aug-17 DroID_v2017_08 Drer\psmd3 Scer\RPN3 "Cele\Y38C1AA.12, Cele\rpn-3" Xtro\psmd3 Mmus\Psmd3 Hsap\PSMD3 DRSC03318 IEK -3.072967016 -2.161496591 -2.378906512 -1.502394518 0.545816097 -2.63213844 FBgn0058167 CG40167 - http://flybase.org/reports/FBgn0058167 protein_coding_gene - - - CG40167 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034839 CG13540 - http://flybase.org/reports/FBgn0034839 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13540 - CG13540 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002397 l(3)96Fa lethal (3) 96Fa http://flybase.org/reports/FBgn0002397 - gene - - - "l(3)C1, l(3)96Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267767 CR46098 - http://flybase.org/reports/FBgn0267767 non_protein_coding_gene - - - CR46098 - CR46098 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050375 CG30375 - http://flybase.org/reports/FBgn0050375 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP80, CG2280, CG30375" "IPR000859:CUB domain, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG30375 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\si:dkey-78l4.10" - Cele\svh-1 - "Mmus\Tmprss7, Mmus\Tmprss6, Mmus\St14, Mmus\Hgfac" "Hsap\ST14, Hsap\TMPRSS7, Hsap\TMPRSS6" viable FBgn0019629 C62 C62 http://flybase.org/reports/FBgn0019629 - gene - - - C62 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "scutum,dorsocentral bristle,posterior postalar bristle,scutellar bristle,macrochaeta" FBgn0037121 Rpb8 Rpb8 http://flybase.org/reports/FBgn0037121 protein_coding_gene - transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9195 inferred from sequence or structural similarity with SGD:S000005750 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9195 inferred from sequence or structural similarity with SGD:S000005750" "RPB8, CG11246, Rpb8" "IPR005570:RNA polymerase, Rpb8, IPR012340:Nucleic acid-binding, OB-fold" CG11246 11-Aug-17 DroID_v2017_08 Drer\polr2h Scer\RPB8 Cele\rpb-8 Xtro\polr2h Mmus\Polr2h Hsap\POLR2H lethal DRSC11642 IEK -1.310579089 2.207122293 -0.995848603 -1.839451888 2.473319941 1.434588309 FBgn0002799 ms(1)14 male sterile (1) 14 http://flybase.org/reports/FBgn0002799 - gene - - - ms(1)14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile,viable" spermatid FBgn0038540 CG14321 - http://flybase.org/reports/FBgn0038540 protein_coding_gene - - - CG14321 IPR031985:Domain of unknown function DUF4787 CG14321 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038412 Zip89B Zinc/iron regulated transporter-related protein 89B http://flybase.org/reports/FBgn0038412 protein_coding_gene metal ion transmembrane transporter activity ; GO:0046873 | inferred from electronic annotation with InterPro:IPR003689 zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003689 metal ion transport ; GO:0030001 | inferred from electronic annotation with InterPro:IPR003689 detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay "ZIP3, CG6898, Zip3, dZip89B, Zip89B, cg6898, dZip3, dZIP89B" IPR003689:Zinc/iron permease CG6898 11-Aug-17 DroID_v2017_08 "Drer\slc39a1, Drer\slc39a3" "Scer\ZRT2, Scer\WSS1, Scer\ZRT1" "Cele\Y54G9A.4, Cele\C18A3.2, Cele\F55F8.9, Cele\F31C3.4, Cele\F30B5.7, Cele\C06G8.3" "Xtro\slc39a2, Xtro\slc39a1, Xtro\slc39a1, Xtro\slc39a3" "Mmus\Slc39a3, Mmus\Slc39a1, Mmus\Slc39a2" "Hsap\SLC39A1, Hsap\SLC39A2, Hsap\SLC39A3" "viable,developmental rate defective" FBgn0262473 Tl Toll http://flybase.org/reports/FBgn0262473 protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from electronic annotation with InterPro:IPR027202 protein binding ; GO:0005515 | inferred from physical interaction with wek protein binding ; GO:0005515 | inferred from physical interaction with Tehao transmembrane signaling receptor activity ; GO:0004888 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with spz cytokine binding ; GO:0019955 | traceable author statement TIR domain binding ; GO:0070976 | inferred from physical interaction with Myd88 defense response to Gram-positive bacterium ; GO:0050830 | inferred from electronic annotation with InterPro:IPR027202 zygotic specification of dorsal/ventral axis ; GO:0007352 | inferred from electronic annotation with InterPro:IPR027202 Toll signaling pathway ; GO:0008063 | inferred from electronic annotation with InterPro:IPR027202 larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement defense response ; GO:0006952 | traceable author statement heart development ; GO:0007507 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | traceable author statement positive regulation of antifungal peptide biosynthetic process ; GO:0006967 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | traceable author statement hemopoiesis ; GO:0030097 | traceable author statement regulation of embryonic pattern specification ; GO:1902875 | inferred from mutant phenotype regulation of melanization defense response ; GO:0035007 | traceable author statement defense response to fungus ; GO:0050832 | traceable author statement positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | non-traceable author statement dorsal/ventral axis specification ; GO:0009950 | traceable author statement antifungal humoral response ; GO:0019732 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | non-traceable author statement antimicrobial humoral response ; GO:0019730 | inferred from genetic interaction with imd dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from direct assay synapse assembly ; GO:0007416 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype response to fungus ; GO:0009620 | traceable author statement defense response to oomycetes ; GO:0002229 | inferred from mutant phenotype innate immune response ; GO:0045087 | non-traceable author statement hemocyte proliferation ; GO:0035172 | traceable author statement response to bacterium ; GO:0009617 | non-traceable author statement hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype innate immune response ; GO:0045087 | traceable author statement regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype zygotic specification of dorsal/ventral axis ; GO:0007352 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with spz early endosome ; GO:0005769 | inferred from direct assay plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay external side of plasma membrane ; GO:0009897 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay "Tl, tl, Toll, TOL, dToll1, Toll-1, toll, toll-1, T1, CG5490, dToll, CT17414, Fs(1)Tl, mel(3)9, mel(3)10, mat(3)9, Fs(3)Tl, TL, Toll1, EP1051, EP(3)1051" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR000372:Leucine-rich repeat N-terminal domain, IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR026906:Leucine rich repeat 5, IPR027202:Protein toll" CG5490 11-Aug-17 DroID_v2017_08 "Drer\tlr3, Drer\LOC100332583, Drer\tlr1, Drer\tlr20.2, Drer\tlr7, Drer\tlr4bb, Drer\tlr18, Drer\tlr4ba, Drer\tlr22, Drer\lrriq1, Drer\tlr9, Drer\tlr2, Drer\LOC100005571, Drer\cd180, Drer\tlr8b, Drer\tlr5b, Drer\zgc:101569, Drer\LOC572462, Drer\tlr5a, Drer\tlr21, Drer\LOC100332783" - Cele\tol-1 "Xtro\LOC100485164, Xtro\tlr6, Xtro\LOC100485201, Xtro\LOC100485706, Xtro\LOC100495326, Xtro\tlr7, Xtro\tlr5, Xtro\tlr2, Xtro\LOC100485512, Xtro\tlr3, Xtro\tlr9" "Mmus\Tlr7, Mmus\Tlr8, Mmus\Tlr3, Mmus\Tlr4, Mmus\Cd180, Mmus\Tlr13, Mmus\Tlr1, Mmus\Tlr2, Mmus\Nrros, Mmus\Vasn, Mmus\Tlr11, Mmus\Tlr12, Mmus\Il1rapl2, Mmus\Tlr9, Mmus\Tlr5, Mmus\Tlr6" "Hsap\TLR4, Hsap\NRROS, Hsap\TLR6, Hsap\TLR10, Hsap\VASN, Hsap\TLR5, Hsap\CD180, Hsap\LRRC3, Hsap\TLR1, Hsap\TLR2, Hsap\TLR3, Hsap\IL1RAPL2, Hsap\TLR9, Hsap\TLR7, Hsap\TLR8" embryonic stage&&pupal stage " embryonic stage | syncytial blastoderm , embryonic stage | embryonic cycle < 13 , embryonic stage | embryonic cycle 14 " FBgn0051028 CG31028 - http://flybase.org/reports/FBgn0051028 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001424 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001424 superoxide metabolic process ; GO:0006801 | inferred from electronic annotation with InterPro:IPR001424 - "CG2176, CG31028" "IPR001424:Superoxide dismutase, copper/zinc binding domain" CG31028 11-Aug-17 DroID_v2017_08 Drer\si:dkey-16m19.2 - Cele\F47G3.1 Xtro\LOC100495179 - - viable FBgn0266358 CR45006 - http://flybase.org/reports/FBgn0266358 non_protein_coding_gene - - - CR45006 - CR45006 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011906 tRNA:Leu-CAG-1-1 transfer RNA:Leucine-CAG 1-1 http://flybase.org/reports/FBgn0011906 "FBgn0050292, FBgn0060154" tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "tRNA[Leu][[2]], AE002787.trna30-LeuCAG, tRNA:L:CAG:AE002787, CR30292, tRNA:leu2:44EF, tRNA[Leu], tRNA[LEU], chr2R.trna12-LeuCAG, tRNA-Leu-CAG-1-1, tRNA:Leu-CAG-1-1, tRNA:L2:44EF, CUG" - CR30292 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036525 CG13451 - http://flybase.org/reports/FBgn0036525 protein_coding_gene - - - "CG13451, FBgn0036525" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015908 bangdoo bangdoo http://flybase.org/reports/FBgn0015908 - gene - biological_process ; GO:0008150 | no biological data available - bangdoo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067733 l(1)G0497 lethal (1) G0497 http://flybase.org/reports/FBgn0067733 gene - - - l(1)G0497 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0010086 SteXh Stellate in X heterochromatin http://flybase.org/reports/FBgn0010086 "FBgn0014123, FBgn0005668" repeat_region - - - "HMR, HMR-element, Ste het, Stellate 1; Stellate 2, Stellate 1, Stellate, SCLR, hSte, Ste2, Ste1, anon-Xh1, SteXh, Ste, hetSte" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052772 CG32772 - http://flybase.org/reports/FBgn0052772 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG15469, CG6911, CG32772" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG32772 11-Aug-17 DroID_v2017_08 "Drer\znf384l, Drer\zgc:171901" Scer\PZF1 "Cele\blmp-1, Cele\M03D4.4, Cele\lin-48" "Xtro\znf568, Xtro\LOC100496354" "Mmus\Ovol2, Mmus\Zfp266" "Hsap\OVOL2, Hsap\ZNF384" viable FBgn0037055 CG10519 - http://flybase.org/reports/FBgn0037055 protein_coding_gene - - - "BcDNA:GM10489, CG10519" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065867 l(2)SH0263 lethal (2) SH0263 http://flybase.org/reports/FBgn0065867 gene - - - "l(2)SH0263, l(2)SH2 0263" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020599 anon-3Bc anon-3Bc http://flybase.org/reports/FBgn0020599 - gene - - - "I, anon-3Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083035 snoRNA:Psi18S-525d snoRNA:Psi18S-525d http://flybase.org/reports/FBgn0083035 snoRNA_gene - - - "snoRNA:Psi18S-525d, psi18S-525d, CR34575" - CR34575 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036773 CG13698 - http://flybase.org/reports/FBgn0036773 protein_coding_gene - - - CG13698 - CG13698 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060421 l(3)S128010b lethal (3) S128010b http://flybase.org/reports/FBgn0060421 gene - - - "1280/10, l(3)S128010b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0051464 CG31464 - http://flybase.org/reports/FBgn0051464 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG11673, CG31464" - CG31464 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060863 l(3)S047331 lethal (3) S047331 http://flybase.org/reports/FBgn0060863 gene - - - "0473/31, l(3)S047331" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0032916 CG9257 - http://flybase.org/reports/FBgn0032916 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay CG9257 IPR021720:Malectin CG9257 11-Aug-17 DroID_v2017_08 Drer\mlec - Cele\F44E2.10 Xtro\mlec Mmus\Mlec Hsap\MLEC viable FBgn0001090 bnb bangles and beads http://flybase.org/reports/FBgn0001090 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism development ; GO:0007275 | inferred from mutant phenotype gliogenesis ; GO:0042063 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "bnb, Gap43, CG7088, GAP43, Bnb" - CG7088 11-Aug-17 DroID_v2017_08 Drer\si:ch211-140m22.7 - - - Mmus\Akap14 Hsap\SMTNL1 embryonic stage " epidermis

, mesectoderm

, embryonic central nervous system

, subesophageal ganglion

, supraesophageal ganglion

, amnioserosa

, glial cell

" "lethal,heat sensitive" "embryonic epidermis,presumptive embryonic/larval central nervous system" FBgn0267012 CR45456 - http://flybase.org/reports/FBgn0267012 non_protein_coding_gene - - - CR45456 - CR45456 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013435 Cdc2rk Cdc2-related kinase http://flybase.org/reports/FBgn0013435 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | non-traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 protein phosphorylation ; GO:0006468 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from biological aspect of ancestor with PANTHER:PTN000623092 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity" mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000623092 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG1362, Dcdrk, cdc2rk, Cdc2rk" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG1362 11-Aug-17 DroID_v2017_08 "Drer\cdk10, Drer\cog5, Drer\cdk11b" "Scer\KDX1, Scer\SSN3, Scer\CDC28" "Cele\cdk-4, Cele\dyf-18, Cele\cdk-11.1, Cele\cdk-11.2, Cele\K09F6.4" "Xtro\cdk10, Xtro\cdk11b" "Mmus\Cog5, Mmus\Cdk10, Mmus\Cdk11b" "Hsap\CDK11B, Hsap\CDK10, Hsap\CDK11A" " embryonic stage , embryonic stage -- adult stage "

ubiquitous viable FBgn0000555 E(f) Enhancer of forked http://flybase.org/reports/FBgn0000555 - gene - - - "If, I-f, E(f)" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,reduced,fertile,poor" "macrochaeta,posterior scutellar bristle" FBgn0259956 Sfp24C1 Seminal fluid protein 24C1 http://flybase.org/reports/FBgn0259956 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp24C1, CG42466" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42466 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038700 CG3734 - http://flybase.org/reports/FBgn0038700 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR008758 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008758 - CG3734 "IPR008758:Peptidase S28, IPR029058:Alpha/Beta hydrolase fold" CG3734 11-Aug-17 DroID_v2017_08 "Drer\prss16, Drer\prss16" - "Cele\F56F10.1, Cele\pcp-1, Cele\F19C7.4, Cele\pcp-4, Cele\F28E10.5, Cele\pcp-5, Cele\C26B9.5, Cele\pcp-2, Cele\F19C7.2, Cele\K12H4.7, Cele\pcp-3" "Xtro\prss16, Xtro\LOC100145763" "Mmus\Dpp7, Mmus\Prss16" "Hsap\PRSS16, Hsap\DPP7" "viable,visible" trichogen cell FBgn0263461 snoRNA:CG32479-a - http://flybase.org/reports/FBgn0263461 snoRNA_gene - - - "snoRNA:CG32479-a, chr3L:874744..875006" - CR43576 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065821 l(2)SH0367 lethal (2) SH0367 http://flybase.org/reports/FBgn0065821 gene - - - "l(2)SH0367, l(2)SH2 0367" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060509 l(3)S104315 lethal (3) S104315 http://flybase.org/reports/FBgn0060509 gene - - - "1043/15, l(3)S104315" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262035 CG42846 - http://flybase.org/reports/FBgn0262035 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42846 - CG42846 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019791 l(1)12 lethal (1) 12 http://flybase.org/reports/FBgn0019791 - gene - - - "tsl(1)12, l(1)12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,heat sensitive,lethal,male,recessive" primary gonial cell FBgn0031489 CG17224 - http://flybase.org/reports/FBgn0031489 protein_coding_gene uridine phosphorylase activity ; GO:0004850 | inferred from electronic annotation with InterPro:IPR010059 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 nucleotide catabolic process ; GO:0009166 | inferred from electronic annotation with InterPro:IPR010059 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010059 CG17224 "IPR000845:Nucleoside phosphorylase domain, IPR010059:Uridine phosphorylase, eukaryotic" CG17224 11-Aug-17 DroID_v2017_08 "Drer\upp2, Drer\upp1" - Cele\upp-1 "Xtro\upp1, Xtro\upp2" "Mmus\Upp1, Mmus\Upp2" "Hsap\UPP1, Hsap\UPP2" viable FBgn0039269 veli veli http://flybase.org/reports/FBgn0039269 protein_coding_gene - regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | inferred from biological aspect of ancestor with PANTHER:PTN001019267 protein localization to basolateral plasma membrane ; GO:1903361 | inferred from biological aspect of ancestor with PANTHER:PTN001019267 establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement maintenance of epithelial cell apical/basal polarity ; GO:0045199 | inferred from biological aspect of ancestor with PANTHER:PTN001019267 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype subapical complex ; GO:0035003 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from biological aspect of ancestor with PANTHER:PTN001019267 postsynaptic membrane ; GO:0045211 | inferred from direct assay "CG7662, DLin-7, Lin-7, Flin-7, d-Veli, Dveli, D-veli, lin-7, veli, lin7, dVeli, Veli, dLin7, dLin-7, DLin7" "IPR001478:PDZ domain, IPR004172:L27 domain, IPR014775:L27 domain, C-terminal" CG7662 11-Aug-17 DroID_v2017_08 "Drer\gopc, Drer\lin7a, Drer\lin7b, Drer\pdzd11, Drer\lin7c" - "Cele\lin-7, Cele\ZK849.1" "Xtro\lin7b, Xtro\lin7a, Xtro\pdlim1, Xtro\pdzd11" "Mmus\Lin7c, Mmus\Lin7b, Mmus\Lin7a, Mmus\Pdlim3, Mmus\Sntb1, Mmus\Pdzd11, Mmus\Mpp4, Mmus\Gopc" "Hsap\MPP3, Hsap\MPP4, Hsap\PDZD11, Hsap\LIN7C, Hsap\GOPC, Hsap\LIN7B, Hsap\LIN7A" "viable,fertile,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "eye photoreceptor cell,neuromuscular junction,trichogen cell,border follicle cell,chaeta,supernumerary" FBgn0025790 TBPH TAR DNA-binding protein-43 homolog http://flybase.org/reports/FBgn0025790 - protein_coding_gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity GU repeat RNA binding ; GO:1990605 | inferred from direct assay larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from mutant phenotype inferred from genetic interaction with futsch inferred from physical interaction with futsch synapse assembly ; GO:0007416 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype negative regulation of RNA splicing ; GO:0033119 | inferred from direct assay neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of intracellular steroid hormone receptor signaling pathway ; GO:0033143 | inferred from mutant phenotype inferred from genetic interaction with Map205 inferred from physical interaction with Map205 positive regulation of dendrite development ; GO:1900006 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay H zone ; GO:0031673 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "CG10327, dtar, TBPH, dTDP-43, tbph, dTDP, TDP-43, TDP43, dmTDP43" IPR000504:RNA recognition motif domain CG10327 11-Aug-17 DroID_v2017_08 "Drer\tardbp, Drer\tardbpl" Scer\DDR48 "Cele\tdp-1, Cele\sqd-1" Xtro\tardbp Mmus\Tardbp Hsap\TARDBP " pupal stage , embryonic stage " "locomotor behavior defective,neuroanatomy defective,partially lethal - majority die,some die during pharate adult stage,viable,learning defective,lethal,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,visible,increased cell death,fertile,recessive,short lived,lethal - all die before end of P-stage,some die during third instar larval stage,gravitaxis defective,jump response defective,neurophysiology defective,progressive" "NMJ bouton,lobe system of adult mushroom body,NMJ bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage,eye,embryonic/larval neuromuscular junction | larval stage,NMJ bouton | larval stage,synaptic vesicle | larval stageD42,motor neuron | larval stage,ommatidium,type I bouton,embryonic/larval neuromuscular junction,ring neuron,progressive,adult mushroom body,axoney-OK107" FBgn0065046 snoRNA:U3:9B snoRNA:U3:9B http://flybase.org/reports/FBgn0065046 snoRNA_gene - - - "Dm-830, CR33662, snoRNA:U3:9B, snoRNA U3, U3 snoRNA, U3-snoRNA, 9B U3 snoRNA, chrX:10193506..10193607" - CR33662 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065313 l(2)SH1936 lethal (2) SH1936 http://flybase.org/reports/FBgn0065313 gene - - - l(2)SH1936 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262768 Su(E1)-B - http://flybase.org/reports/FBgn0262768 gene - - - Su(E1)-B - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039816 CG11317 - http://flybase.org/reports/FBgn0039816 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG11317 IPR013087:Zinc finger C2H2-type CG11317 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0035313 CG13810 - http://flybase.org/reports/FBgn0035313 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13810 - CG13810 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267940 CR46220 - http://flybase.org/reports/FBgn0267940 non_protein_coding_gene - - - "CR46220, lincRNA.906" - CR46220 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001819 l(1)rr lethal (1) ring gland rudimentary http://flybase.org/reports/FBgn0001819 - gene - - - l(1)rr - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" ring gland FBgn0260310 GSd459 - http://flybase.org/reports/FBgn0260310 gene - - - GSd459 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038313 CG4338 - http://flybase.org/reports/FBgn0038313 protein_coding_gene - maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000463956 - CG4338 "IPR007177:Ribosome biogenesis protein, C-terminal, IPR007209:RNase L inhibitor RLI, possible metal-binding domain, IPR022968:Ribosome biogenesis protein" CG4338 11-Aug-17 DroID_v2017_08 Drer\tsr3 Scer\TSR3 Cele\F52C12.2 Xtro\tsr3 Mmus\Tsr3 Hsap\TSR3 "viable,fertile" FBgn0004058 olfF olfactory F http://flybase.org/reports/FBgn0004058 - gene - - - olfF - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,recessive" FBgn0022371 Pt-3 Larval protein-3 http://flybase.org/reports/FBgn0022371 - gene - - - Pt-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010421 TfIIFbeta Transcription factor TFIIFbeta http://flybase.org/reports/FBgn0010421 FBgn0011350 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011039 transcription factor activity, core RNA polymerase II binding ; GO:0000991 | inferred from biological aspect of ancestor with PANTHER:PTN000047872 TFIIF-class transcription factor binding ; GO:0001096 | inferred from physical interaction with TfIIFα" positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay positive regulation of transcription initiation from RNA polymerase II promoter ; GO:0060261 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4653 inferred from sequence or structural similarity with SGD:S000003237 transcription factor TFIIF complex ; GO:0005674 | inferred from direct assay transcription factor TFIIF complex ; GO:0005674 | inferred from sequence or structural similarity with HGNC:4653 inferred from sequence or structural similarity with SGD:S000003237 nucleus ; GO:0005634 | inferred from direct assay "RAP30, TFIIF, F[[S]], CG6538, dTFIIF30, TfIIFbeta, TFIIFbeta, l(3)j3C1, TfIIF, T2FB_DROME" "IPR003196:Transcription initiation factor IIF, beta subunit, IPR011039:Transcription Factor IIF, Rap30/Rap74, interaction, IPR011991:Winged helix-turn-helix DNA-binding domain" CG6538 11-Aug-17 DroID_v2017_08 "Drer\gtf2f2a, Drer\gtf2f2b" Scer\TFG2 Cele\Y39B6A.36 Xtro\gtf2f2 Mmus\Gtf2f2 Hsap\GTF2F2 "lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0005486 l(1)ts1681 lethal (1) ts1681 http://flybase.org/reports/FBgn0005486 - gene - - - l(1)ts1681 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0260759 CG42557 - http://flybase.org/reports/FBgn0260759 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7866, CG42557" IPR028039:Coiled-coil domain containing protein 32 CG42557 11-Aug-17 DroID_v2017_08 Drer\ccdc32 - - Xtro\c15orf57 Mmus\Ccdc32 Hsap\C15orf57 FBgn0039811 CG15550 - http://flybase.org/reports/FBgn0039811 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15550 - CG15550 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0002485 l(3)SG45 lethal (3) SG45 http://flybase.org/reports/FBgn0002485 FBgn0004725 gene - - - "l(3)dsl-5, l(3)7m-68, l(3)dsl5, l(3)SG45" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,mitotic cell cycle,cell cycle" FBgn0082810 Dmc dymeclin http://flybase.org/reports/FBgn0082810 gene - - - "dDMC, Dmc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262830 LAS110 - http://flybase.org/reports/FBgn0262830 nuclear_gene - regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype - LAS110 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male limited" FBgn0029183 E(Khc)ek3 E(Khc)ek3 http://flybase.org/reports/FBgn0029183 gene - - - E(Khc)ek3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067422 E(TS2)2 E(TS2)2 http://flybase.org/reports/FBgn0067422 gene - - - E(TS2)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044380 anon-AE002870.1 anon-AE002870.1 http://flybase.org/reports/FBgn0044380 gene - - - anon-AE002870.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261509 haf hattifattener http://flybase.org/reports/FBgn0261509 protein_coding_gene - motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype - "CG14351, haf, tartan/capricious-like, CT33985" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype" CG14351 11-Aug-17 DroID_v2017_08 "Drer\lrig2, Drer\lrig1" - Cele\egg-6 "Xtro\lrig2, Xtro\lrig1, Xtro\lrig3" "Mmus\Lrig1, Mmus\Tlr12, Mmus\Lrig2, Mmus\Lrrc43, Mmus\Lrig3" "Hsap\LRIG3, Hsap\LRIG2, Hsap\LRIG1, Hsap\TRIL, Hsap\LRRC43" FBgn0027580 PCB Pyruvate carboxylase http://flybase.org/reports/FBgn0027580 FBgn0033455 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR005479, InterPro:IPR005930, InterPro:IPR011761, InterPro:IPR011764, InterPro:IPR013815, InterPro:IPR013816 biotin binding ; GO:0009374 | inferred from electronic annotation with InterPro:IPR005930 biotin carboxylase activity ; GO:0004075 | inferred from electronic annotation with InterPro:IPR011764 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011761 pyruvate carboxylase activity ; GO:0004736 | inferred from sequence or structural similarity with UniProtKB:P11498 pyruvate carboxylase activity ; GO:0004736 | inferred from direct assay" gluconeogenesis ; GO:0006094 | inferred from electronic annotation with InterPro:IPR005930 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:P11498 mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P11498 "CG1516, PC, BcDNA, BcDNA:GH06348, PCB, Q0E9E2_DROME, dPC" "IPR000089:Biotin/lipoyl attachment, IPR000891:Pyruvate carboxyltransferase, IPR001882:Biotin-binding site, IPR003379:Carboxylase, conserved domain, IPR005479:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain, IPR005481:Biotin carboxylase-like, N-terminal domain, IPR005482:Biotin carboxylase, C-terminal, IPR005930:Pyruvate carboxylase, IPR011053:Single hybrid motif, IPR011054:Rudiment single hybrid motif, IPR011761:ATP-grasp fold, IPR011764:Biotin carboxylation domain, IPR013785:Aldolase-type TIM barrel, IPR016185:Pre-ATP-grasp domain, IPR013815:ATP-grasp fold, subdomain 1" CG1516 11-Aug-17 DroID_v2017_08 "Drer\pcxa, Drer\pcxb, Drer\mccc1, Drer\pcca" "Scer\PYC2, Scer\DUR1,2, Scer\PYC1" "Cele\pcca-1, Cele\mccc-1, Cele\pyc-1" Xtro\pc.2 "Mmus\Mccc1, Mmus\Pcx, Mmus\Pcca" "Hsap\MCCC1, Hsap\PC, Hsap\PCCA" "partially lethal - majority die,some die during pupal stage" FBgn0002762 mit(1)12 mitotic 12 http://flybase.org/reports/FBgn0002762 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0262397 mir-2c mir-2c stem loop http://flybase.org/reports/FBgn0262397 miRNA_gene - negative regulation of translational initiation ; GO:0045947 | inferred from direct assay negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "mir-2c, MIR-2, CR42936, miR-2, CR33560, miR-2c, miR2, miR2c, dme-mir-2c, dme-miR-2c" - CR42936 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage viable FBgn0039531 CG5611 - http://flybase.org/reports/FBgn0039531 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001753 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR001753 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG5611 "IPR001753:Crotonase superfamily, IPR029045:ClpP/crotonase-like domain" CG5611 11-Aug-17 DroID_v2017_08 Drer\zgc:101569 "Scer\DCI1, Scer\ECI1" "Cele\ech-3, Cele\ech-5" "Xtro\LOC100135367, Xtro\LOC100488770" Mmus\Echdc2 Hsap\ECHDC2 DRSC15843 E 1.449253694 -0.802747175 1.734222086 1.050123633 -1.279591895 -0.70113598 FBgn0030291 CG1738 - http://flybase.org/reports/FBgn0030291 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE11532, CG1738" IPR027973:Protein of unknown function DUF4602 CG1738 11-Aug-17 DroID_v2017_08 Drer\zgc:194224 - - Xtro\c1orf131 Mmus\2810004N23Rik Hsap\C1orf131 "viable,visible" trichogen cell FBgn0002158 l(2)pm lethal (2) polymorph http://flybase.org/reports/FBgn0002158 - gene - - - l(2)pm - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "pupa,muscle system" FBgn0013231 E(var)182 E(var)182 http://flybase.org/reports/FBgn0013231 - gene - - - E(var)182 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0013541 l(2)ry53 lethal (2) ry53 http://flybase.org/reports/FBgn0013541 - gene - - - "l(2)53, l(2)ry53" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001935 l(2)25Fa lethal (2) 25Fa http://flybase.org/reports/FBgn0001935 - gene - - - "l(2)TE9, l(2)gdh-14, l(2)25Fa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259413 C167 - http://flybase.org/reports/FBgn0259413 gene - - - C167 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing,chaeta" FBgn0003329 scd sex combs distal http://flybase.org/reports/FBgn0003329 - gene - - - "l(1)9Fd, scd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "prothoracic tarsal segment 2 & sex comb,sex comb,ectopic" FBgn0024692 fs(1)ne11 fs(1)ne11 http://flybase.org/reports/FBgn0024692 - gene - - - "ne11, fs(1)ne11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" oocyte FBgn0044499 DTD44.4 DTD44.4 http://flybase.org/reports/FBgn0044499 gene - - - DTD44.4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069084 sbe schraube http://flybase.org/reports/FBgn0069084 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sbe - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0042155 CG18832 - http://flybase.org/reports/FBgn0042155 protein_coding_gene - - - CG18832 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086033 snoRNA:Me28S-A2486 - http://flybase.org/reports/FBgn0086033 snoRNA_gene - - - "snoRNA:Me28S-A2486, Me28S-Am2486, Me28S-A2486, CR34662" - CR34662 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085204 CG34175 - http://flybase.org/reports/FBgn0085204 protein_coding_gene - - - CG34175 - CG34175 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052195 CG32195 - http://flybase.org/reports/FBgn0052195 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32195 "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG32195 11-Aug-17 DroID_v2017_08 - - "Cele\dhs-27, Cele\E02C12.8, Cele\Y45G12C.4, Cele\nhr-246, Cele\C18B10.6, Cele\E02C12.9, Cele\E02C12.6, Cele\F58B4.5, Cele\H06H21.8, Cele\F56A4.5, Cele\H37A05.2, Cele\F49C12.7, Cele\C29F7.1, Cele\C29F7.2, Cele\E02C12.10" - - - viable FBgn0277432 M95 - http://flybase.org/reports/FBgn0277432 gene - - - M95 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069313 X-200-22 X-200-22 http://flybase.org/reports/FBgn0069313 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-200-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8" FBgn0031129 CG1324 - http://flybase.org/reports/FBgn0031129 protein_coding_gene - - - "anon-WO0140519.192, CG1324" - CG1324 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,body color defective" mesothoracic tergum FBgn0001992 Cyp303a1 Cyp303a1 http://flybase.org/reports/FBgn0001992 FBgn0032583 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 sensory organ development ; GO:0007423 | inferred from mutant phenotype" - "CYP303A1-Dm, nompH, 303a1, l(2)35Fb, I(2)35Fb, BG:DS02740.6, CG4163, Cyp303a1, Cyp303A1" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG4163 11-Aug-17 DroID_v2017_08 "Drer\cyp2p7, Drer\cyp2r1, Drer\cyp2x6, Drer\cyp2k19, Drer\cyp2aa8, Drer\cyp1b1, Drer\cyp17a2, Drer\cyp1a, Drer\cyp2ae1, Drer\cyp2aa9, Drer\cyp2ad6, Drer\cyp2k6, Drer\cyp2aa12, Drer\cyp2k22, Drer\LOC100148115, Drer\cyp2x8, Drer\cyp2k20, Drer\cyp2ad2, Drer\cyp2y3, Drer\cyp21a2, Drer\cyp2p8, Drer\cyp2k18, Drer\cyp2aa4, Drer\cyp2k17, Drer\cyp2aa11, Drer\cyp2p6, Drer\cyp2x10.2, Drer\cyp2k21, Drer\si:dkey-286h2.7, Drer\cyp2x12, Drer\cyp2aa3, Drer\cyp2n13, Drer\cyp17a1, Drer\si:zfos-411a11.2, Drer\cyp2u1, Drer\cyp2p9, Drer\cyp2aa1, Drer\cyp2j20, Drer\cyp2x7, Drer\cyp2aa2, Drer\cyp2p10, Drer\cyp2k31, Drer\cyp2k16, Drer\cyp1d1, Drer\cyp2x9, Drer\cyp2k8" - "Cele\cyp-14A2, Cele\cyp-14A5, Cele\cyp-33C4, Cele\cyp-33D3, Cele\cyp-33C6, Cele\daf-9, Cele\cyp-33E1, Cele\cyp-33C7, Cele\cyp-33C11, Cele\cyp-33D1, Cele\cyp-14A3, Cele\cyp-33C2, Cele\cyp-14A1, Cele\cyp-33C12, Cele\cyp-33E2, Cele\cyp-33C3, Cele\cyp-33C1, Cele\cyp-33C8, Cele\cyp-36A1, Cele\cyp-33C5" "Xtro\cyp2e1, Xtro\LOC100036663, Xtro\cyp2g1p, Xtro\LOC100493194, Xtro\LOC100497184, Xtro\LOC100145541, Xtro\cyp2a6, Xtro\LOC100486127, Xtro\cyp2w1, Xtro\LOC100145323, Xtro\MGC69353, Xtro\cyp2a13, Xtro\MGC107969, Xtro\cyp2d6, Xtro\cyp2f2, Xtro\LOC100497460, Xtro\cyp21a2.1, Xtro\MGC69416, Xtro\cyp1b1, Xtro\LOC100145084, Xtro\cyp2b6, Xtro\cyp1a1, Xtro\cyp2c8.1, Xtro\LOC619584, Xtro\cyp2c8.2, Xtro\cyp2r1, Xtro\cyp17a1, Xtro\cyp1d1, Xtro\cyp2u1, Xtro\cyp2j2, Xtro\LOC548374, Xtro\LOC100145695" "Mmus\Cyp2c38, Mmus\Cyp1b1, Mmus\Cyp2c66, Mmus\Cyp2c67, Mmus\Cyp2d40, Mmus\Cyp2c29, Mmus\Cyp2b9, Mmus\Cyp2d12, Mmus\Cyp2j5, Mmus\Cyp2c39, Mmus\Cyp2j8, Mmus\Cyp2c40, Mmus\Cyp2j11, Mmus\Cyp2b19, Mmus\Cyp2c70, Mmus\Cyp2a5, Mmus\Cyp2c54, Mmus\Cyp2b23, Mmus\Cyp2d26, Mmus\Cyp2s1, Mmus\Cyp2d11, Mmus\Cyp2d34, Mmus\Cyp2g1, Mmus\Cyp2c44, Mmus\Cyp2c69, Mmus\Cyp2f2, Mmus\Cyp2a12, Mmus\Cyp2c55, Mmus\Cyp2a4, Mmus\Cyp2j12, Mmus\Cyp2d22, Mmus\Cyp2j6, Mmus\Cyp2c50, Mmus\Cyp2ab1, Mmus\Cyp17a1, Mmus\Cyp1a1, Mmus\Cyp2d10, Mmus\Cyp2j13, Mmus\Cyp2u1, Mmus\Cyp2c65, Mmus\Cyp2d9, Mmus\Cyp2b10, Mmus\Cyp2c68, Mmus\Cyp2r1, Mmus\Cyp2e1, Mmus\Cyp21a1, Mmus\Cyp2j9, Mmus\Cyp2c37, Mmus\Cyp2t4, Mmus\Cyp1a2, Mmus\Cyp2a22, Mmus\Cyp2w1, Mmus\Cyp2b13" "Hsap\CYP2B6, Hsap\CYP2R1, Hsap\CYP1A2, Hsap\CYP2F1, Hsap\CYP17A1, Hsap\CYP1B1, Hsap\CYP2D6, Hsap\CYP2A7, Hsap\CYP2S1, Hsap\CYP1A1, Hsap\CYP2E1, Hsap\CYP2U1, Hsap\CYP2A6, Hsap\CYP2C18, Hsap\CYP2J2, Hsap\CYP2C9, Hsap\CYP2W1, Hsap\CYP2C19, Hsap\CYP2C8, Hsap\CYP2A13, Hsap\CYP21A2" "uncoordinated,flightless,locomotor behavior defective,neurophysiology defective,partially lethal - majority die,recessive,lethal,neuroanatomy defective,chemosensitive behavior defective" "wing,macrochaeta,socket,trichogen cell" FBgn0000938 fs(2)A8 female sterile (2) A8 http://flybase.org/reports/FBgn0000938 - gene - - - fs(2)A8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0036643 Syx8 Syntaxin 8 http://flybase.org/reports/FBgn0036643 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity vesicle docking ; GO:0048278 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 vesicle fusion ; GO:0006906 | inferred from sequence or structural similarity with RGD:61917 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 neurogenesis ; GO:0022008 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with RGD:61917 SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 "DmSyx8, CG4109, Dm Syx8, Syx8, Syx, SYX8" IPR000727:Target SNARE coiled-coil homology domain CG4109 11-Aug-17 DroID_v2017_08 "Drer\stx10, Drer\stx6, Drer\stx8" "Scer\VAM7, Scer\SYN8, Scer\TLG1" - "Xtro\stx8, Xtro\stx6, Xtro\stx10" "Mmus\Stx6, Mmus\Stx8" "Hsap\STX10, Hsap\STX8, Hsap\STX6" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0065579 l(2)SH0943 lethal (2) SH0943 http://flybase.org/reports/FBgn0065579 gene - - - l(2)SH0943 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058388 CG40388 - http://flybase.org/reports/FBgn0058388 protein_coding_gene - - - CG40388 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002903 mus306 mutagen-sensitive 306 http://flybase.org/reports/FBgn0002903 - gene - double-strand break repair ; GO:0006302 | inferred from mutant phenotype - mus306 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,DNA repair defective,fertile,semidominant,female fertile" FBgn0065491 l(2)SH1233 lethal (2) SH1233 http://flybase.org/reports/FBgn0065491 gene - - - l(2)SH1233 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067085 K34 K34 http://flybase.org/reports/FBgn0067085 gene - - - K34 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable" FBgn0015439 l(1)5DEa lethal (1) 5DEa http://flybase.org/reports/FBgn0015439 - gene - - - l(1)5DEa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000358 Cp19 Chorion protein 19 http://flybase.org/reports/FBgn0000358 - protein_coding_gene - "multicellular organism development ; GO:0007275 | inferred from electronic annotation with InterPro:IPR005649, InterPro:IPR009611" "chorion ; GO:0042600 | inferred from electronic annotation with InterPro:IPR005649, InterPro:IPR009611" "Cp19, s19, CP19, CG6524, Dms19, cp19, C.s19, s19-1, S19" "IPR009611:Chorion S19, C-terminal, IPR005649:Chorion 2" CG6524 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage | >=stage S10 , adult stage | female , adult stage | female && oogenesis stage | stage S13-14 " follicle cell

adult stage | female " ovary

{ 0 swa6 } , ovary

, ovary

{ v mus101K451 } , ovary

{ v fs(1)A1059K1 } " viable FBgn0001360 l(1)1EFi lethal (1) 1EFi http://flybase.org/reports/FBgn0001360 - gene - - - "l(1)BA9, l(1)1EFi" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001843 l(1)ts1843 lethal (1) ts1843 http://flybase.org/reports/FBgn0001843 - gene - - - l(1)ts1843 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060323 l(3)S146705 lethal (3) S146705 http://flybase.org/reports/FBgn0060323 gene - - - "1467/05, l(3)S146705" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259449 C407 - http://flybase.org/reports/FBgn0259449 gene - - - C407 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0036522 CG7372 - http://flybase.org/reports/FBgn0036522 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG7372 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7372 11-Aug-17 DroID_v2017_08 "Drer\ikzf5, Drer\ikzf1, Drer\mynn, Drer\si:dkey-14d8.1, Drer\si:ch211-191d2.2, Drer\si:dkey-166n8.9, Drer\si:ch211-266d19.4, Drer\si:zfos-1425h8.1" - "Cele\Y55F3AM.14, Cele\hinf-1" "Xtro\ikzf3, Xtro\ikzf4, Xtro\zbtb11, Xtro\ikzf1, Xtro\ikzf2, Xtro\znf630" "Mmus\Zfp691, Mmus\Rbak, Mmus\Ikzf2, Mmus\Ikzf4, Mmus\Mynn, Mmus\Ikzf3, Mmus\Ikzf5, Mmus\Ikzf1, Mmus\Zfp507, Mmus\9130023H24Rik" "Hsap\GLI4, Hsap\IKZF4, Hsap\MYNN, Hsap\IKZF3, Hsap\ZNF691, Hsap\IKZF1, Hsap\IKZF2" "viable,visible" mesothoracic tergum FBgn0011845 tRNA:Asp-GTC-1-11 transfer RNA:Aspartic acid-GTC 1-11 http://flybase.org/reports/FBgn0011845 "FBgn0051540, FBgn0060257" tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "CR31540, tRNA[Asp], Asp.tRNA, AE002708.trna30-AspGTC, tRNA:D:GTC:AE002708-a, tRNA:asp:96A, tRNA[[Asp]], tRNA[Asp-GTC], chr3R.trna36-AspGTC, tRNA:Asp-GTC-1-11, tRNA:D:96A, tRNA-Asp-GTC-1-11, GAC" - CR31540 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060657 l(3)S082808b lethal (3) S082808b http://flybase.org/reports/FBgn0060657 gene - - - "0828/08, l(3)S082808b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004486 l(1)air13 lethal aberrant immune response 13 http://flybase.org/reports/FBgn0004486 - gene - - - "air13, l(1)air[13], l(1)air13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,melanotic mass phenotype" "embryonic/larval brain,melanotic mass,embryonic/larval lymph gland" FBgn0001307 Ki Kinked http://flybase.org/reports/FBgn0001307 - gene - - - Ki - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,dominant,heat sensitive,fertile" "macrochaeta,microchaeta" FBgn0261058 Sfp38D Seminal fluid protein 38D http://flybase.org/reports/FBgn0261058 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp38D, CG42606" IPR019617:Domain of unknown function DUF2489 CG42606 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043029 l(2)42Ea lethal (2) 42Ea http://flybase.org/reports/FBgn0043029 gene - - - l(2)42Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052507 CG32507 - http://flybase.org/reports/FBgn0052507 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32507 - CG32507 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051573 tRNA:Pro-TGG-1-3 transfer RNA:Proline-TGG 1-3 http://flybase.org/reports/FBgn0051573 tRNA_gene CCA codon-amino acid adaptor activity ; GO:0033423 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033423 cytosol ; GO:0005829 | inferred by curator from GO:0033423 "AE002708.trna13-ProTGG, tRNA:-?:90Ce, tRNA:P:TGG:AE002708-b, CR31573, chr3R.trna19-ProTGG, tRNA-Pro-TGG-1-3, tRNA:Pro-TGG-1-3, tRNA:CR31573, CCA" - CR31573 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030979 CG14190 - http://flybase.org/reports/FBgn0030979 protein_coding_gene - - - CG14190 - CG14190 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016773 anon-70Db anon-70Db http://flybase.org/reports/FBgn0016773 - gene - - - "gamma1, anon-70Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030816 CG16700 - http://flybase.org/reports/FBgn0030816 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 neurogenesis ; GO:0022008 | inferred from mutant phenotype amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 CG16700 "IPR013057:Amino acid transporter, transmembrane domain" CG16700 11-Aug-17 DroID_v2017_08 "Drer\slc36a1, Drer\slc36a4" "Scer\AVT3, Scer\AVT4" "Cele\slc-36.2, Cele\Y18D10A.23, Cele\skat-1, Cele\slc-36.5, Cele\slc-36.3, Cele\Y43F4B.7, Cele\slc-36.4" "Xtro\slc36a4, Xtro\slc36a1" "Mmus\Slc36a2, Mmus\Slc36a4, Mmus\Slc36a1, Mmus\Slc36a3" "Hsap\SLC36A3, Hsap\SLC36A2, Hsap\SLC36A1, Hsap\SLC36A4" "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0019870 l(3)96Ad lethal (3) 96Ad http://flybase.org/reports/FBgn0019870 - gene - - - "291.3, anon-96Ad, l(3)96Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052071 CG32071 - http://flybase.org/reports/FBgn0052071 protein_coding_gene - - - "CG6261, CG32071" - CG32071 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083994 CR41352 - http://flybase.org/reports/FBgn0083994 non_protein_coding_gene - - - "CG41352, CR41352" - CR41352 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037127 CG14566 - http://flybase.org/reports/FBgn0037127 protein_coding_gene - - - CG14566 - CG14566 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035624 Eaf6 Esa1-associated factor 6 http://flybase.org/reports/FBgn0035624 protein_coding_gene histone acetyltransferase activity (H3-K23 specific) ; GO:0043994 | inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay regulation of cell cycle ; GO:0051726 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay MOZ/MORF histone acetyltransferase complex ; GO:0070776 | inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | colocalizes_with inferred from direct assay "dEaf6, CG12756, Eaf6" IPR015418:Chromatin modification-related protein Eaf6 CG12756 11-Aug-17 DroID_v2017_08 Drer\meaf6 Scer\EAF6 Cele\B0025.4 Xtro\meaf6 Mmus\Meaf6 Hsap\MEAF6 "viable,visible" mesothoracic tergum FBgn0267873 CR46161 - http://flybase.org/reports/FBgn0267873 pseudogene_attribute - - - CR46161 - CR46161 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260987 vtd verthandi http://flybase.org/reports/FBgn0260987 protein_coding_gene chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000286904 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with SGD:S000002161 mitotic sister chromatid cohesion ; GO:0007064 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from genetic interaction with hh neuron remodeling ; GO:0016322 | inferred from mutant phenotype mitotic sister chromatid cohesion ; GO:0007064 | non-traceable author statement mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype synaptonemal complex organization ; GO:0070193 | inferred from mutant phenotype double-strand break repair ; GO:0006302 | inferred from biological aspect of ancestor with PANTHER:PTN000286904 "cohesin complex ; GO:0008278 | non-traceable author statement pericentric heterochromatin ; GO:0005721 | inferred from direct assay cohesin complex ; GO:0008278 | inferred from direct assay nuclear cohesin complex ; GO:0000798 | inferred from biological aspect of ancestor with PANTHER:PTN000286904 nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | non-traceable author statement synaptonemal complex ; GO:0000795 | inferred from direct assay" "RAD21, CG17436, Rad21, vtd, rad21, lethal 3, l(3)80Fh, l3, l(3)Lh3, 80Fh, drad21, DRAD21, Scc1, DmRAD21, dRad21, Drad21, DRad21, scc1, CG40222, Rad21/Scc1, VTD, Vtd" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR006909:Rad21/Rec8-like protein, C-terminal, eukaryotic, IPR006910:Rad21/Rec8-like protein, N-terminal" CG17436 11-Aug-17 DroID_v2017_08 "Drer\rec8b, Drer\rad21a, Drer\rad21b, Drer\rad21l1" "Scer\MCD1, Scer\REC8" "Cele\coh-1, Cele\scc-1" "Xtro\rec8, Xtro\rad21" "Mmus\Rad21, Mmus\Rad21l, Mmus\Rec8" "Hsap\RAD21, Hsap\REC8, Hsap\RAD21L1" " embryonic stage | stage 10 , larval stage | third instar , adult stage | male , embryonic stage | stage >=12 , embryonic stage | stage 11-14 , adult stage | female , embryonic stage , embryonic stage | stage 12 , pupal stage " " neuroblast

ventral compartment , eye-antennal disc | restricted

, midgut primordium

, embryonic brain

, embryonic/larval midgut | restricted

, embryonic/larval hindgut | restricted

, ventral nerve cord

, procephalic neuroblast

, neuroblast &&of larval brain

, inclusive hindgut primordium

" FBgn0260011 NimC4 Nimrod C4 http://flybase.org/reports/FBgn0260011 protein_coding_gene phosphatidylserine binding ; GO:0001786 | inferred from direct assay "engulfment of apoptotic cell ; GO:0043652 | inferred from mutant phenotype phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from sequence or structural similarity with NimC1 apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG16876, simu, BG:DS05899.3, CT35247, NimC4, nimC4" IPR000742:EGF-like domain CG16876 11-Aug-17 DroID_v2017_08 "Drer\zgc:158328, Drer\megf11, Drer\megf6b, Drer\megf10, Drer\pear1, Drer\tnfaip6, Drer\dkk1a, Drer\megf6a, Drer\esm1, Drer\ccbe1, Drer\scarf1, Drer\dkk2" - "Cele\ZK1193.3, Cele\R09H10.5, Cele\B0393.5, Cele\Y34B4A.5" "Xtro\stab2, Xtro\megf11, Xtro\tnfaip6" "Mmus\Egfem1, Mmus\Megf6, Mmus\Megf11, Mmus\Pear1, Mmus\Stab1, Mmus\Scarf1, Mmus\Megf10, Mmus\Dkk3, Mmus\Esm1, Mmus\Tnfaip6, Mmus\Megf8, Mmus\Dkk2" "Hsap\MEGF11, Hsap\TNFAIP6, Hsap\DKK2, Hsap\SCARF2, Hsap\PEAR1, Hsap\SCARF1, Hsap\MEGF6, Hsap\MEGF10, Hsap\MEGF8" FBgn0027345 fs(2)E9a fs(2)E9a http://flybase.org/reports/FBgn0027345 FBgn0000962 gene - - - "fs2.9, fs(2)E9, fs(2)E9a" - - 11-Aug-17 DroID_v2017_08 - - - - - - female fertile FBgn0038491 CG5292 - http://flybase.org/reports/FBgn0038491 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR016193 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002125 - - "BcDNA:RE41712, CG5292" "IPR002125:Cytidine and deoxycytidylate deaminases, zinc-binding, IPR016193:Cytidine deaminase-like" CG5292 11-Aug-17 DroID_v2017_08 "Drer\adat2, Drer\smug1" "Scer\TAD2, Scer\TAD3, Scer\FCY1, Scer\RKM5" "Cele\Y48A6B.7, Cele\R13A5.10, Cele\JC8.4" "Xtro\adat2, Xtro\smug1" "Mmus\Adat2, Mmus\Smug1" "Hsap\SMUG1, Hsap\ADAT2" viable FBgn0030272 CG15201 - http://flybase.org/reports/FBgn0030272 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model "BcDNA:RH06304, CG15201, DIGF-5" - CG15201 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260307 GSd328 - http://flybase.org/reports/FBgn0260307 gene - - - GSd328 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0082830 DC238 DC238 http://flybase.org/reports/FBgn0082830 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available DC238 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265254 CR44268 - http://flybase.org/reports/FBgn0265254 non_protein_coding_gene - - - CR44268 - CR44268 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031265 CG2794 - http://flybase.org/reports/FBgn0031265 protein_coding_gene "hydrolase activity, acting on glycosyl bonds ; GO:0016798 | inferred from electronic annotation with InterPro:IPR007342 phosphotransferase activity, alcohol group as acceptor ; GO:0016773 | inferred from electronic annotation with InterPro:IPR002173" biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2794 "IPR002173:Carbohydrate/puine kinase, PfkB, conserved site, IPR007342:Pseudouridine-5'-phosphate glycosidase, IPR011611:Carbohydrate kinase PfkB, IPR029056:Ribokinase-like" CG2794 11-Aug-17 DroID_v2017_08 Drer\zgc:136858 - "Cele\R07H5.8, Cele\T24C12.3" Xtro\LOC100485794 - - "partially lethal - majority die,some die during pupal stage" FBgn0039635 CG11876 - http://flybase.org/reports/FBgn0039635 protein_coding_gene pyruvate dehydrogenase (acetyl-transferring) activity ; GO:0004739 | inferred from sequence or structural similarity with UniProtKB:P08559 acetyl-CoA biosynthetic process from pyruvate ; GO:0006086 | inferred from electronic annotation with InterPro:IPR027110 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:P29803 cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay pyruvate dehydrogenase complex ; GO:0045254 | inferred from sequence or structural similarity with UniProtKB:P08559 microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG11876, E1beta, PDHB, CG 11876" "IPR005475:Transketolase-like, pyrimidine-binding domain, IPR009014:Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II, IPR013177:Domain of unknown function DUF1713, IPR027110:Pyruvate dehydrogenase E1 component subunit beta, IPR029061:Thiamin diphosphate-binding fold, IPR033248:Transketolase, C-terminal domain" CG11876 11-Aug-17 DroID_v2017_08 Drer\pdhb Scer\PDB1 Cele\pdhb-1 Xtro\pdhb Mmus\Pdhb Hsap\PDHB "wing disc | third instar larval stage,mitochondrionen-e16E" FBgn0016824 l(1)MZ11 lethal (1) MZ11 http://flybase.org/reports/FBgn0016824 - gene - - - "l(1)MZ11, M11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020569 anon-88Aa anon-88Aa http://flybase.org/reports/FBgn0020569 - gene - - - anon-88Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061108 l(3)S007818b lethal (3) S007818b http://flybase.org/reports/FBgn0061108 gene - - - "0078/18, l(3)S007818b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029535 CG14635 - http://flybase.org/reports/FBgn0029535 protein_coding_gene - - - CG14635 - CG14635 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC17945 I 1.74071811 -0.67331785 0.016961067 0.180855488 1.333578398 0.465194152 FBgn0022714 22w 22w http://flybase.org/reports/FBgn0022714 - gene - - - 22w - - 11-Aug-17 DroID_v2017_08 - - - - - - mitotic cell cycle defective "nuclear chromosome,larval brain & nuclear chromosome" FBgn0004045 Yp1 Yolk protein 1 http://flybase.org/reports/FBgn0004045 - protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 sex differentiation ; GO:0007548 | non-traceable author statement sex differentiation ; GO:0007548 | traceable author statement extracellular region ; GO:0005576 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Yp1, CG2985, YP, yp1, yp, YPI, yp-1, DmYP1, YP1, YP-1, YP[[1]], VG1, fs(1)1163, fs(1)A1163, VIT1Dm, GH19966p" "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG2985 11-Aug-17 DroID_v2017_08 "Drer\pla1a, Drer\lipia, Drer\LOC101884800, Drer\lipg, Drer\lipca, Drer\lpl, Drer\LOC100331214, Drer\lipib" - - "Xtro\lpl, Xtro\lipg" "Mmus\Pnlip, Mmus\Lipi, Mmus\Lipg, Mmus\Pnliprp1, Mmus\Lipc, Mmus\Pla1a, Mmus\Lpl, Mmus\Pnliprp2, Mmus\Liph" "Hsap\LIPC, Hsap\LPL, Hsap\PLA1A, Hsap\PNLIPRP1, Hsap\LIPI, Hsap\LIPH, Hsap\PNLIPRP2, Hsap\PNLIPRP3, Hsap\LIPG, Hsap\PNLIP" "electrophoretic variant,female sterile,dominant,heat sensitive,recessive,female sterile soma-dependent,viable,body color defective" "adult fat body,heat sensitive,egg,mesothoracic tergum" FBgn0060981 l(3)S028317 lethal (3) S028317 http://flybase.org/reports/FBgn0060981 gene - - - "0283/17, l(3)S028317" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023025 l(2)KN13 lethal (2) KN13 http://flybase.org/reports/FBgn0023025 - gene - - - l(2)KN13 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267210 CR45650 - http://flybase.org/reports/FBgn0267210 non_protein_coding_gene - - - CR45650 - CR45650 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083024 snoRNA:Psi18S-640c snoRNA:Psi18S-640c http://flybase.org/reports/FBgn0083024 snoRNA_gene - - - "snoRNA:Psi18S-640c, psi18s-640c, CR34576" - CR34576 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261575 tobi target of brain insulin http://flybase.org/reports/FBgn0261575 protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR000322" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000322 - "CG11909, tobi, CT33098" "IPR000322:Glycoside hydrolase family 31, IPR017853:Glycoside hydrolase superfamily" CG11909 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-117c19.1, Drer\gaa, Drer\si:dkey-228b2.5, Drer\si:ch211-236l14.4, Drer\si:ch73-12o23.1" Scer\ROT2 - "Xtro\mgam, Xtro\kiaa1161, Xtro\gaa" "Mmus\Sis, Mmus\AI464131, Mmus\Gaa, Mmus\Mgam" "Hsap\GAA, Hsap\SI, Hsap\MGAM2, Hsap\KIAA1161, Hsap\MGAM" FBgn0033485 RpLP0-like Ribosomal protein LP0-like http://flybase.org/reports/FBgn0033485 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement cytoplasmic translation ; GO:0002181 | traceable author statement rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000474869 translation ; GO:0006412 | inferred by curator from GO:0022625 nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from biological aspect of ancestor with PANTHER:PTN000474869 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000474869 cytosolic large ribosomal subunit ; GO:0022625 | inferred from sequence or structural similarity with HGNC:10371 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000474869 "FBgn0033485, CG1381, RpLP0-like" "IPR001790:Ribosomal protein L10P, IPR033867:Ribosome assembly factor Mrt4" CG1381 11-Aug-17 DroID_v2017_08 Drer\mrto4 Scer\MRT4 Cele\F10E7.5 Xtro\mrto4 Mmus\Mrto4 Hsap\MRTO4 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0030541 CG11584 - http://flybase.org/reports/FBgn0030541 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with MGI:MGI:1201690 dendrite morphogenesis ; GO:0048813 | inferred from sequence or structural similarity with HGNC:6868 microtubule ; GO:0005874 | inferred from sequence or structural similarity with HGNC:6868 CG11584 IPR022727:Pupal cuticle protein C1 CG11584 11-Aug-17 DroID_v2017_08 "Drer\map6a, Drer\map6d1, Drer\pou2af1" - "Cele\ZK1010.5, Cele\Y49E10.29, Cele\T23E7.2, Cele\C49A9.5" Xtro\map6 "Mmus\Map6d1, Mmus\Pou2af1, Mmus\Phc3" "Hsap\MAP6D1, Hsap\SNAP91, Hsap\MAP6, Hsap\POU2AF1" "partially lethal - majority die,some die during pupal stage" FBgn0259742 CG42360 - http://flybase.org/reports/FBgn0259742 protein_coding_gene - - - "CG42360, CG13588, CG3579" "IPR021869:Ribonuclease Zc3h12a-like, NYN domain" CG42360 11-Aug-17 DroID_v2017_08 "Drer\zc3h12b, Drer\n4bp1, Drer\si:dkey-206d17.12, Drer\ccdc59, Drer\khnyn" - "Cele\Y59E9AR.2, Cele\C29F5.3, Cele\Y59E9AR.8, Cele\rde-8, Cele\Y24D9B.1, Cele\Y51H4A.13, Cele\C30F12.1" "Xtro\zc3h12b, Xtro\zc3h12a, Xtro\n4bp1, Xtro\khnyn" "Mmus\Zc3h12d, Mmus\Ccdc59, Mmus\Khnyn, Mmus\Zc3h12b, Mmus\N4bp1, Mmus\Zc3h12a, Mmus\Zc3h12c, Mmus\Nynrin" "Hsap\KHNYN, Hsap\NYNRIN, Hsap\ZC3H12C, Hsap\N4BP1, Hsap\ZC3H12A, Hsap\ZC3H12D, Hsap\ZC3H12B, Hsap\CCDC59" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0265680 CR44487 - http://flybase.org/reports/FBgn0265680 non_protein_coding_gene - - - "lincRNA.185, CR44487" - CR44487 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085212 CG34183 - http://flybase.org/reports/FBgn0085212 protein_coding_gene CTD phosphatase activity ; GO:0008420 | inferred from sequence or structural similarity with HGNC:25791 dephosphorylation of RNA polymerase II C-terminal domain ; GO:0070940 | inferred from sequence or structural similarity with HGNC:25791 snRNA transcription ; GO:0009301 | inferred from sequence or structural similarity with HGNC:25791 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:25791 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:25791 CG34183 IPR007308:Protein of unknown function DUF408 CG34183 11-Aug-17 DroID_v2017_08 Drer\rpap2 "Scer\RTR1, Scer\RTR2" Cele\R08D7.2 Xtro\rpap2 Mmus\Rpap2 Hsap\RPAP2 FBgn0025124 su(RpII140[Z36])S4 su(RpII140[Z36])S4 http://flybase.org/reports/FBgn0025124 - gene - - - "Z36[S4], su(RpII140[Z36])S4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262482 CG43072 - http://flybase.org/reports/FBgn0262482 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43072, chr3L_21058978_21059336.0" - CG43072 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004664 ms(3)HO5A male sterile (3) HO5A http://flybase.org/reports/FBgn0004664 "FBgn0002834, FBgn0002836, FBgn0005313" gene - - - "ms(3)m1, ms(3)ml[5A], ms(1)m1, ms(3)HO5A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" testis FBgn0028081 l(3)S085301 lethal (3) S085301 http://flybase.org/reports/FBgn0028081 gene - - - "0853/01, l(3)S085301" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027195 l(2)39CDa lethal (2) 39CDa http://flybase.org/reports/FBgn0027195 - gene - - - l(2)39CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035781 CG8560 - http://flybase.org/reports/FBgn0035781 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "CT14378, CG8560" "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG8560 11-Aug-17 DroID_v2017_08 "Drer\cpa5, Drer\cpa1, Drer\cpo, Drer\cpa6, Drer\cpa2, Drer\cpa4, Drer\cpb2, Drer\cpb1" Scer\ECM14 "Cele\Y59C2A.1, Cele\suro-1, Cele\W01A8.6, Cele\T06A4.1, Cele\ZC434.9, Cele\F02D8.4, Cele\Y47G6A.19, Cele\T06A4.3, Cele\Y18H1A.9" "Xtro\cpb1, Xtro\cpo, Xtro\cpa3, Xtro\cpb2, Xtro\cpa1" "Mmus\Cpa4, Mmus\Cpb2, Mmus\Cpa3, Mmus\Cpb1, Mmus\Cpa5, Mmus\Cpa2, Mmus\Cpa6, Mmus\Cpa1" "Hsap\CPA4, Hsap\CPA3, Hsap\CPA5, Hsap\CPA2, Hsap\CPB1, Hsap\CPA1, Hsap\CPB2, Hsap\CPO, Hsap\CPA6" viable FBgn0024563 l(3)L6332 lethal (3) L6332 http://flybase.org/reports/FBgn0024563 - gene - - - l(3)L6332 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086026 snoRNA:Me28S-G2596 - http://flybase.org/reports/FBgn0086026 snoRNA_gene - - - "snoRNA:Me28S-G2596, Me28S-Gm2596, CR34655" - CR34655 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014997 snRNA:U1:21D::snRNA:U1:82Ea snRNA:U1:21D::snRNA:U1:82Ea http://flybase.org/reports/FBgn0014997 - engineered_fusion_gene - - - snRNA:U1:21D::snRNA:U1:82Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023048 l(1)3Ao lethal (1) 3Ao http://flybase.org/reports/FBgn0023048 - gene - - - "A2/4, l(1)3Ao" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267915 CR46196 - http://flybase.org/reports/FBgn0267915 non_protein_coding_gene - - - "CR46196, lincRNA.60" - CR46196 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259551 B1512 - http://flybase.org/reports/FBgn0259551 gene - - - B1512 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing vein L3,wing margin,wing sensillum,ectopic,tarsal segment,antennal segment,arista,leg,third segment of antenna,chaeta" FBgn0000982 fs(2)HO297 female sterile (2) HO297 http://flybase.org/reports/FBgn0000982 - gene - - - "fs(2)297A, fs(2)HO297" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034318 CG14500 - http://flybase.org/reports/FBgn0034318 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - CG14500 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG14500 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085740 CR40508 - http://flybase.org/reports/FBgn0085740 rRNA_gene - - - CR40508 - CR40508 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265676 CR44483 - http://flybase.org/reports/FBgn0265676 non_protein_coding_gene - - - CR44483 - CR44483 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267703 CR46036 - http://flybase.org/reports/FBgn0267703 non_protein_coding_gene - - - CR46036 - CR46036 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069439 EMS2 EMS2 http://flybase.org/reports/FBgn0069439 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available EMS2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086036 snoRNA:Me18S-A934 - http://flybase.org/reports/FBgn0086036 snoRNA_gene - - - "snoRNA:Me18S-A934, Me18S-Am934, CR34665" - CR34665 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023055 l(1)3ABa lethal (1) 3ABa http://flybase.org/reports/FBgn0023055 - gene - - - "D3/22.61, A2/7, l(1)3ABa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0087011 CG41520 - http://flybase.org/reports/FBgn0087011 protein_coding_gene transmembrane receptor protein tyrosine kinase activator activity ; GO:0030297 | inferred from sequence or structural similarity with HGNC:487 activation of transmembrane receptor protein tyrosine kinase activity ; GO:0007171 | inferred from sequence or structural similarity with HGNC:487 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with HGNC:487 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:487 "CG41520, CG40067, CG17443, CG40109" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG41520 11-Aug-17 DroID_v2017_08 "Drer\fga, Drer\angptl1a, Drer\si:zfos-2330d3.1, Drer\angptl6, Drer\mfap4, Drer\zgc:194887, Drer\fgl2a, Drer\fgl2b, Drer\si:dkeyp-51b7.3, Drer\zgc:171687, Drer\angptl1b, Drer\angptl4, Drer\si:zfos-2330d3.3, Drer\tnr, Drer\si:zfos-2330d3.6, Drer\tnw, Drer\angpt2a, Drer\wu:fj11g02, Drer\angptl7, Drer\angpt2b, Drer\fgg, Drer\fibcd1, Drer\angptl3, Drer\angptl2a, Drer\fgl1, Drer\angptl5, Drer\si:ch211-157b11.8, Drer\angpt4, Drer\si:ch1073-110a20.2, Drer\si:ch1073-110a20.1, Drer\tnxba, Drer\zmp:0000000846, Drer\angpt1, Drer\tnc, Drer\fgb, Drer\si:ch211-287a12.9, Drer\LOC100007488, Drer\LOC555374, Drer\angptl2b, Drer\si:ch211-203k16.3, Drer\zgc:173915" - "Cele\T15B7.1, Cele\T01D3.1, Cele\ensh-1" "Xtro\fga, Xtro\LOC100491105, Xtro\tnn, Xtro\fgg, Xtro\tnxb, Xtro\fgl1, Xtro\fibcd1, Xtro\fcn2, Xtro\angpt2, Xtro\angpt4, Xtro\LOC100497330, Xtro\angptl2, Xtro\fgb, Xtro\tnc, Xtro\tnr, Xtro\LOC100488177, Xtro\fcn1, Xtro\angptl5, Xtro\angpt1, Xtro\fgl2, Xtro\fcn3, Xtro\angptl4, Xtro\angptl3, Xtro\mfap4" "Mmus\Tnc, Mmus\Tnn, Mmus\Angptl4, Mmus\Angpt1, Mmus\Angptl1, Mmus\Fgg, Mmus\Tnxb, Mmus\Angpt2, Mmus\Angptl7, Mmus\Angpt4, Mmus\Fibcd1, Mmus\Fcnb, Mmus\Fgl1, Mmus\Angptl3, Mmus\Fga, Mmus\Angptl2, Mmus\Fcna, Mmus\Fgb, Mmus\Fgl2, Mmus\Tnr, Mmus\Angptl6, Mmus\Mfap4" "Hsap\ANGPTL1, Hsap\TNC, Hsap\FGG, Hsap\TNR, Hsap\FCN1, Hsap\ANGPT1, Hsap\ANGPT4, Hsap\FIBCD1, Hsap\ANGPTL2, Hsap\ANGPTL5, Hsap\MFAP4, Hsap\ANGPTL6, Hsap\FGL2, Hsap\FGB, Hsap\FGL1, Hsap\FCN3, Hsap\FGA, Hsap\FCN2, Hsap\ANGPTL7, Hsap\TNXB, Hsap\TNN, Hsap\ANGPTL4, Hsap\ANGPTL3, Hsap\ANGPT2" FBgn0032509 CG6523 - http://flybase.org/reports/FBgn0032509 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR002109 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR002109 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR002109, InterPro:IPR013766" - "CG6523, Grx3, Grx4" "IPR002109:Glutaredoxin, IPR004480:Monothiol glutaredoxin-related, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR033658:Glutaredoxin, PICOT-like" CG6523 11-Aug-17 DroID_v2017_08 "Drer\glrx5, Drer\glrx3" "Scer\GRX5, Scer\GRX3, Scer\GRX4" "Cele\glrx-5, Cele\glrx-3" "Xtro\glrx3, Xtro\glrx5" "Mmus\Glrx3, Mmus\Glrx5" "Hsap\GLRX5, Hsap\GLRX3" viable FBgn0021876 l(2)k13704 lethal (2) k13704 http://flybase.org/reports/FBgn0021876 - gene - - - l(2)k13704 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011051 l(1)Q4 lethal (1) Q4 http://flybase.org/reports/FBgn0011051 FBgn0010210 gene - - - l(1)Q4 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020526 mit(3)R72 mitotic R72 http://flybase.org/reports/FBgn0020526 - gene - - - mit(3)R72 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085239 CG34210 - http://flybase.org/reports/FBgn0085239 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34210 IPR029375:Protein of unknown function DUF4558 CG34210 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014252 l(2)60Ae lethal (2) 60Ae http://flybase.org/reports/FBgn0014252 - gene - - - l(2)60Ae - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0030768 CG9723 - http://flybase.org/reports/FBgn0030768 protein_coding_gene - - nuclear envelope ; GO:0005635 | inferred from biological aspect of ancestor with PANTHER:PTN001006264 CG9723 IPR019358:NEMP family CG9723 11-Aug-17 DroID_v2017_08 "Drer\nemp2, Drer\nemp1" - Cele\F10C5.2 Xtro\nemp1 "Mmus\Nemp1, Mmus\Nemp2" "Hsap\NEMP1, Hsap\NEMP2" viable FBgn0259178 5PtaseI 5PtaseI http://flybase.org/reports/FBgn0259178 protein_coding_gene inositol-polyphosphate 5-phosphatase activity ; GO:0004445 | inferred from mutant phenotype inositol trisphosphate phosphatase activity ; GO:0046030 | non-traceable author statement phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from electronic annotation with InterPro:IPR000300 dephosphorylation ; GO:0016311 | non-traceable author statement inositol phosphate-mediated signaling ; GO:0048016 | inferred from biological aspect of ancestor with PANTHER:PTN000313248 inositol phosphate dephosphorylation ; GO:0046855 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000313248 "CG42283, dm5PtaseI, CG31107, 5PtaseI, IPP, CG7613, BcDNA:RE64196, CG31110" "IPR000300:Inositol polyphosphate-related phosphatase, IPR005135:Endonuclease/exonuclease/phosphatase" CG42283 11-Aug-17 DroID_v2017_08 Drer\inpp5l - "Cele\C01B10.3, Cele\ipp-5" "Xtro\inpp5a.1, Xtro\inpp5a.2" Mmus\Inpp5a Hsap\INPP5A FBgn0028239 l(3)S001925 lethal (3) S001925 http://flybase.org/reports/FBgn0028239 gene - - - "0019/25, l(3)S001925" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0021971 l(2)k10003a lethal (2) k10003a http://flybase.net/reports/FBgn0021971.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0027538 beta4GalNAcTA beta4GalNAcTA http://flybase.org/reports/FBgn0027538 FBgn0062226 protein_coding_gene "acetylgalactosaminyltransferase activity ; GO:0008376 | inferred from direct assay N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity ; GO:0033842 | inferred from direct assay beta-1,4-N-acetylgalactosaminyltransferase activity ; GO:0033207 | inferred from direct assay" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR003859 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype N-acetylglucosamine metabolic process ; GO:0006044 | inferred from direct assay adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype glycolipid biosynthetic process ; GO:0009247 | inferred from direct assay glycosphingolipid biosynthetic process ; GO:0006688 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay "beta4GalNacTA, beta4GalNAcTA, CG8536, BcDNA:GH13356, dbeta4GalTA, beta4GalTA, anon-WO0118547.128, b4GalNAcTA, beta4Gal-NAcTA, DmGalT, beta4GalNAcT1" "IPR003859:Beta-1,4-galactosyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases, IPR027995:Galactosyltransferase, N-terminal, IPR027791:Galactosyltransferase, C-terminal" CG8536 11-Aug-17 DroID_v2017_08 "Drer\b4galt5, Drer\si:dkey-199f5.8, Drer\b4galt2, Drer\b4galt1, Drer\b4galt3, Drer\b4galt6, Drer\b4galt4, Drer\b4galt1l" Scer\TMA20 Cele\bre-4 "Xtro\b4galt6, Xtro\b4galt4, Xtro\b4galt3, Xtro\b4galt1.1, Xtro\b4galt2, Xtro\b4galt5, Xtro\b4galt1.2" "Mmus\B4galt4, Mmus\B4galt2, Mmus\B4galt5, Mmus\B4galt1, Mmus\B4galt6, Mmus\B4galt3" "Hsap\B4GALT5, Hsap\B4GALT4, Hsap\B4GALT3, Hsap\B4GALT6, Hsap\B4GALT2, Hsap\B4GALT1" "fertile,viable,bang sensitive,locomotor behavior defective,neuroanatomy defective,neurophysiology defective,sleep defective" "embryonic/larval neuromuscular junction,NMJ bouton,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,sarcomere & abdominal ventral longitudinal muscle 3‘_4GalNAcTA20.1),sarcomere & abdominal ventral longitudinal muscle 4‘_4GalNAcTA20.1)" FBgn0010647 l(2)08307a lethal (2) 08307a http://flybase.org/reports/FBgn0010647 - gene - - - "l(2)08307, l(2)08307a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0010041 GstD5 Glutathione S transferase D5 http://flybase.org/reports/FBgn0010041 FBgn0038024 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GstD24, DmGSTD5, CG12242, DmGST24, Gst, GST, gstD24, GstD5, GSTD5, D5, gstd5" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG12242 11-Aug-17 DroID_v2017_08 "Drer\eef1g, Drer\gstr, Drer\vars, Drer\mars, Drer\gstt1a, Drer\eef1e1, Drer\gstt1b, Drer\gstt2" "Scer\TEF4, Scer\URE2, Scer\CAM1, Scer\GTT2, Scer\YGR201C, Scer\GTT1" - "Xtro\eef1e1, Xtro\gstt1, Xtro\eef1g" "Mmus\Mars, Mmus\Gstt4, Mmus\Gstt2, Mmus\Eef1g, Mmus\Gstt1, Mmus\Vars, Mmus\Eef1e1, Mmus\Gstt3" "Hsap\EEF1G, Hsap\GSTT2, Hsap\MARS, Hsap\GSTT1, Hsap\EEF1E1, Hsap\GSTT2B, Hsap\VARS" viable FBgn0085686 CG41555 - http://flybase.org/reports/FBgn0085686 protein_coding_gene - - - CG41555 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039685 Obp99b Odorant-binding protein 99b http://flybase.org/reports/FBgn0039685 protein_coding_gene odorant binding ; GO:0005549 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush olfactory behavior ; GO:0042048 | inferred from sequence or structural similarity with UniProtKB:O02372 response to pheromone ; GO:0019236 | inferred from sequence or structural similarity with UniProtKB:O02372 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 autophagic cell death ; GO:0048102 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:O02372 extracellular region ; GO:0005576 | inferred from sequence model "CG7592, tsx, Obp99d, 99b, BcDNA:LP06572, Obp99b, DmelObp99b, OBP99b, obp99b" IPR006170:Pheromone/general odorant binding protein CG7592 11-Aug-17 DroID_v2017_08 - - - - - - "mating defective,female,viable" DRSC16264 E -0.051477676 -1.147726077 -1.871766633 -0.33853945 0.646867704 -0.792500403 FBgn0039900 Syt7 Synaptotagmin 7 http://flybase.org/reports/FBgn0039900 protein_coding_gene syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium-dependent phospholipid binding ; GO:0005544 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 calcium-dependent phospholipid binding ; GO:0005544 | non-traceable author statement synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 neurotransmitter secretion ; GO:0007269 | non-traceable author statement regulation of calcium ion-dependent exocytosis ; GO:0017158 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 vesicle-mediated transport ; GO:0016192 | non-traceable author statement vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 lysosome ; GO:0005764 | colocalizes_with inferred from direct assay sarcoplasm ; GO:0016528 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity vesicle ; GO:0031982 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "Syt7, dsyt7, CG2381, SYT7, CG10322, Syt VII, Syt 7, syt7" "IPR000008:C2 domain, IPR001565:Synaptotagmin, IPR015427:Synaptotagmin 7" CG2381 11-Aug-17 DroID_v2017_08 "Drer\syt7a, Drer\syt7b, Drer\syt13" - "Cele\snt-6, Cele\sue-1, Cele\T27E4.1" Xtro\syt7 "Mmus\Syt7, Mmus\Syt13" "Hsap\SYT13, Hsap\SYT7" viable FBgn0260779 GatA "Glutamyl-tRNA amidotransferase, subunit A" http://flybase.org/reports/FBgn0260779 protein_coding_gene glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity ; GO:0050567 | inferred from electronic annotation with InterPro:IPR004412 amidase activity ; GO:0004040 | inferred from electronic annotation with InterPro:IPR000120 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR004412 oogenesis ; GO:0048477 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype glutamyl-tRNA(Gln) amidotransferase complex ; GO:0030956 | inferred from electronic annotation with InterPro:IPR004412 mitochondrion ; GO:0005739 | inferred from direct assay "bene, CG6007, benedict, 0929/02, l(3)S092902, GatA, gatA" "IPR000120:Amidase, IPR004412:Glutamyl-tRNA(Gln) amidotransferase A subunit, IPR023631:Amidase signature domain" CG6007 11-Aug-17 DroID_v2017_08 Drer\qrsl1 "Scer\DUR1,2, Scer\HER2" "Cele\Y53F4B.18, Cele\faah-3, Cele\Y41D4A.6, Cele\faah-5" Xtro\qrsl1 Mmus\Qrsl1 Hsap\QRSL1 FBgn0259569 B2022 - http://flybase.org/reports/FBgn0259569 gene - - - B2022 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,tarsal segment" FBgn0001492 l(1)10Bc lethal (1) 10Bc http://flybase.org/reports/FBgn0001492 - gene - - - "10Bb, l(1)GLM15, l(1)G15, l(1)10Bc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" "ovariole,germline clone,egg,dorsal appendage" FBgn0001242 hypoA hypoactive A http://flybase.org/reports/FBgn0001242 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available hypoA - - 11-Aug-17 DroID_v2017_08 - - - - - - "bang sensitive,optomotor response defective,locomotor behavior defective,flight defective" FBgn0259411 C752 - http://flybase.org/reports/FBgn0259411 gene - - - C752 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta,ectopic" FBgn0060600 l(3)S091904b lethal (3) S091904b http://flybase.org/reports/FBgn0060600 gene - - - "0919/04, l(3)S091904b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003459 stwl stonewall http://flybase.org/reports/FBgn0003459 - protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 "heterochromatin organization ; GO:0070828 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype DNA protection ; GO:0042262 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from direct assay polytene chromosome ; GO:0005700 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "snw, fs(3)02024, CG3836, stwl, Stwl, 84" "IPR004210:BESS motif, IPR006578:MADF domain" CG3836 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-207i20.3, Drer\zgc:152938, Drer\LOC100330838" - "Cele\madf-9, Cele\madf-10, Cele\madf-4, Cele\madf-8, Cele\madf-2, Cele\madf-5, Cele\madf-3" - - - " adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-7 " " female germline stem cell

, germarium region 1--3

, oocyte

, nurse cell

" "lethal,heat sensitive,hyperplasia,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,recessive,viable,fertile,neuroanatomy defective,male fertile,suppressor of variegation,dominant,chemical sensitive,female fertile,visible" "wing margin,wing pouch,wing disc,wing hinge,wing hinge primordium,eye,ovary,egg chamber,embryonic/larval salivary gland | larval stage,neurite | pharate adult stage,germline cell,female,heat sensitive,female germline stem cell,somatic clone,supernumerary" FBgn0021830 l(2)k16005 lethal (2) k16005 http://flybase.org/reports/FBgn0021830 - gene - - - l(2)k16005 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267819 CR46144 - http://flybase.org/reports/FBgn0267819 non_protein_coding_gene - - - CR46144 - CR46144 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019766 l(1)54B2 lethal (1) 54B2 http://flybase.org/reports/FBgn0019766 - gene - - - l(1)54B2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037019 Pex16 Peroxin 16 http://flybase.org/reports/FBgn0037019 protein_coding_gene - peroxisome organization ; GO:0007031 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8857 very long-chain fatty acid catabolic process ; GO:0042760 | inferred from mutant phenotype spermatocyte division ; GO:0048137 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype peroxisomal membrane ; GO:0005778 | inferred from biological aspect of ancestor with PANTHER:PTN000329346 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8857 "CG3947, Pex16, DmelPex16, pex16, PEX16" "IPR013919:Peroxisome membrane protein, Pex16" CG3947 11-Aug-17 DroID_v2017_08 Drer\pex16 - - Xtro\pex16 Mmus\Pex16 Hsap\PEX16 "viable,eye color defective,flight defective,recessive,locomotor behavior defective,short lived,neuroanatomy defective,male sterile,small body,fertile,cytokinesis defective" "peroxisomeNP5021,peroxisomenos.UTR.THsimVP16,peroxisome,dendrite,testis,lobula plate" FBgn0013949 Elal Elastin-like http://flybase.org/reports/FBgn0013949 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to nicotine ; GO:0035094 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "CG7021, Ela, Elal" - CG7021 11-Aug-17 DroID_v2017_08 - - "Cele\col-94, Cele\col-108, Cele\T08D2.8, Cele\col-92, Cele\F54A3.2, Cele\col-93" - - - viable FBgn0004187 snRNA:U1:95Cc small nuclear RNA U1 at 95Cc http://flybase.org/reports/FBgn0004187 "FBgn0003915, FBgn0003918, FBgn0051185" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity "U1, U1 snRNA, U1c-95Cc, U1-95.3, U1snRNA, K5, CR31185, snRNA:U1, snRNA-U1-95.3, U1snRNA95Cc, snRNA:U1:95Cc, U1:95Cc, U1:95C, 95C U1" - CR31185 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267111 CR45551 - http://flybase.org/reports/FBgn0267111 non_protein_coding_gene - - - "lincRNA.723, lincRNA.724, CR45551" - CR45551 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035521 VhaM9.7-a Vacuolar H[+] ATPase M9.7 subunit a http://flybase.org/reports/FBgn0035521 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000262636 hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from sequence model with InterPro:IPR008389,InterPro:IPR017385" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model" "proton-transporting V-type ATPase, V0 domain ; GO:0033179 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from biological aspect of ancestor with PANTHER:PTN000262688" "VhaM9.7-a, CG1268, vhaM9.7-1, VhaM9.7-1" "IPR008389:ATPase, V0 complex, subunit e1/e2, IPR017385:ATPase, V0 complex, subunit e1/e2, metazoa" CG1268 11-Aug-17 DroID_v2017_08 "Drer\pars2, Drer\atpv0e2, Drer\atp6v0e1" Scer\VMA9 Cele\vha-17 "Xtro\atp6v0e1, Xtro\atp6v0e2" "Mmus\Atp6v0e, Mmus\Atp6v0e2, Mmus\Pars2" "Hsap\ATP6V0E1, Hsap\ATP6V0E2" "partially lethal - majority die,some die during pupal stage" FBgn0030537 CG12480 - http://flybase.org/reports/FBgn0030537 protein_coding_gene - - - CG12480 - CG12480 11-Aug-17 DroID_v2017_08 "Drer\dscama, Drer\mylk4b, Drer\mylka, Drer\mylk3, Drer\mylk4a, Drer\mylkb" - "Cele\ZC373.4, Cele\unc-89" "Xtro\dscaml1, Xtro\mylk3, Xtro\mylk, Xtro\mylk4, Xtro\dscam" "Mmus\Dscaml1, Mmus\Mylk2, Mmus\Mylk, Mmus\Mylk4, Mmus\Mylk3, Mmus\Dscam" "Hsap\DSCAM, Hsap\MYLK4, Hsap\MYLK, Hsap\MYLK2, Hsap\DSCAML1, Hsap\MYLK3" viable FBgn0000782 fs(1)A1528 female sterile (1) A1528 http://flybase.org/reports/FBgn0000782 - gene - - - fs(1)A1528 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,non-rescuable maternal effect" egg FBgn0015854 anon-12Ea anon-12Ea http://flybase.org/reports/FBgn0015854 - gene - - - anon-12Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023030 l(2)C43 lethal (2) C43 http://flybase.org/reports/FBgn0023030 - gene - - - l(2)C43 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0000740 fs(1)A120 female sterile (1) A120 http://flybase.org/reports/FBgn0000740 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)120, fs(1)571, fs(1)A120" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,female sterile soma-dependent,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect,embryo" FBgn0036677 CG13023 - http://flybase.org/reports/FBgn0036677 protein_coding_gene - - - CG13023 - CG13023 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0283666 Rap2l Ras-associated protein 2-like http://flybase.org/reports/FBgn0283666 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity" Rap protein signal transduction ; GO:0032486 | inferred from sequence or structural similarity with MGI:MGI:1919315 germ-line stem cell population maintenance ; GO:0030718 | inferred from genetic interaction with PDZ-GEF neurogenesis ; GO:0022008 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from sequence or structural similarity with MGI:MGI:1919315 "Rap21, Dm Rap21, CG3204, Rap2l, Rap2L, Rap2, O96692, l(2)SH0581, l(2)SH2 0581" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG3204 11-Aug-17 DroID_v2017_08 "Drer\zgc:153845, Drer\diras2, Drer\rasl11a, Drer\rap2c, Drer\mras, Drer\rheb, Drer\rrad, Drer\hrasa, Drer\rap2ab, Drer\rerglb, Drer\diras1a, Drer\hrasb, Drer\si:dkey-27j5.5, Drer\diras1b, Drer\zgc:152698, Drer\si:dkeyp-59c12.1, Drer\rras2, Drer\rasl11b, Drer\rasd1, Drer\kras, Drer\rsg1, Drer\LOC100332969, Drer\rasl10a, Drer\ralbb, Drer\zgc:110699, Drer\rhebl1, Drer\rap1aa, Drer\rem1, Drer\zgc:64022, Drer\zgc:171704, Drer\ralab, Drer\rap1b, Drer\rap1ab, Drer\rergla, Drer\rit1, Drer\ralaa, Drer\si:ch73-116o1.2, Drer\gem, Drer\rras, Drer\rasl12, Drer\zgc:114118, Drer\rap2b, Drer\rem2, Drer\nras, Drer\ralba" "Scer\RHB1, Scer\RAS1, Scer\RAS2, Scer\RSR1" "Cele\rap-3, Cele\ZK669.5, Cele\Y52B11A.4, Cele\rap-2, Cele\D1081.4" "Xtro\rheb, Xtro\hras, Xtro\rap2b, Xtro\rem2, Xtro\rem1, Xtro\rasd1, Xtro\rerg, Xtro\LOC733456, Xtro\rhebl1, Xtro\nras, Xtro\rala, Xtro\rap2c, Xtro\rasl11b, Xtro\rit1, Xtro\ras-dva, Xtro\rap1a, Xtro\gem, Xtro\rergl, Xtro\rsg1, Xtro\diras2, Xtro\rasd2, Xtro\kras, Xtro\rap1b, Xtro\ralb, Xtro\diras1, Xtro\diras3, Xtro\rrad, Xtro\rap2a, Xtro\rasl10a" "Mmus\Rasl11b, Mmus\Rsg1, Mmus\Rheb, Mmus\Diras1, Mmus\Rasl11a, Mmus\Rras, Mmus\Rit2, Mmus\Mras, Mmus\Rasl10b, Mmus\Rasd2, Mmus\Ralb, Mmus\Rap1a, Mmus\Rasl12, Mmus\Gm266, Mmus\Rem2, Mmus\Gem, Mmus\Rrad, Mmus\Rhebl1, Mmus\Eras, Mmus\Rem1, Mmus\Rap2b, Mmus\Diras2, Mmus\Rap1b, Mmus\Rergl, Mmus\Kras, Mmus\Rap2c, Mmus\Rasl10a, Mmus\Hras, Mmus\Rap2a, Mmus\Nras, Mmus\Rasd1, Mmus\Rit1, Mmus\Rerg, Mmus\Rala, Mmus\Rras2" "Hsap\KRAS, Hsap\RAP2A, Hsap\REM2, Hsap\NRAS, Hsap\RHEB, Hsap\RRAD, Hsap\RRAS, Hsap\RIT1, Hsap\RASL11B, Hsap\RALA, Hsap\RIT2, Hsap\RAP1B, Hsap\RASL12, Hsap\RALB, Hsap\DIRAS3, Hsap\RASD1, Hsap\GEM, Hsap\RAP2B, Hsap\RASD2, Hsap\RASL10A, Hsap\RERGL, Hsap\RAP1A, Hsap\REM1, Hsap\RAP2C, Hsap\DIRAS1, Hsap\RASL10B, Hsap\RERG, Hsap\RRAS2, Hsap\ERAS, Hsap\RASL11A, Hsap\MRAS, Hsap\RHEBL1, Hsap\RSG1, Hsap\DIRAS2, Hsap\HRAS" "lethal,recessive" FBgn0003350 sdx spreadex http://flybase.org/reports/FBgn0003350 - gene - - - "spx, sdx" - - 11-Aug-17 DroID_v2017_08 - - - - - - semi-fertile "wing,abdomen,female" FBgn0083016 snoRNA:Psi18S-841d snoRNA:Psi18S-841d http://flybase.org/reports/FBgn0083016 snoRNA_gene - - - "snoRNA:Psi18S-841d, Psi18S-841d, psi18S-841d, CR34555" - CR34555 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265059 CR44170 - http://flybase.org/reports/FBgn0265059 non_protein_coding_gene - - - CR44170 - CR44170 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069215 gl-l glass-like http://flybase.org/reports/FBgn0069215 gene - - - gl-l - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032271 CG7329 - http://flybase.org/reports/FBgn0032271 protein_coding_gene - - - "CG7329, ORE-4" "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG7329 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH1, Scer\TGL1, Scer\YEH2" "Cele\lipl-4, Cele\lipl-1, Cele\lipl-5, Cele\lipl-6, Cele\lipl-2, Cele\lipl-3, Cele\lipl-7, Cele\lipl-8" Xtro\lipa "Mmus\Lipo1, Mmus\Lipn, Mmus\Lipo2, Mmus\Lipa, Mmus\Lipo3, Mmus\Lipk, Mmus\Lipf, Mmus\Lipo4, Mmus\Lipm" "Hsap\LIPA, Hsap\LIPJ, Hsap\LIPK, Hsap\LIPF, Hsap\LIPM, Hsap\LIPN" viable FBgn0038550 CG17801 - http://flybase.org/reports/FBgn0038550 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG17801 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG17801 11-Aug-17 DroID_v2017_08 "Drer\zgc:66443, Drer\si:ch73-138e16.4, Drer\si:ch211-113e8.10, Drer\znf408, Drer\znf692" "Scer\AZF1, Scer\STP3, Scer\STP4" "Cele\unc-98, Cele\ztf-23, Cele\M03D4.4, Cele\Y55F3AM.14" - Mmus\Zfp91 "Hsap\ZFP91, Hsap\ZNF81, Hsap\ZNF621, Hsap\ZNF157, Hsap\ZNF492, Hsap\ZNF613, Hsap\ZNF860, Hsap\ZNF8, Hsap\ZNF605, Hsap\ZNF195, Hsap\ZNF281, Hsap\ZNF225, Hsap\GFI1B" "viable,fertile,female fertile" FBgn0040014 CG17412 - http://flybase.org/reports/FBgn0040014 protein_coding_gene - - - CG17412 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082363 EP605 EP605 http://flybase.org/reports/FBgn0082363 gene - - - EP605 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0266494 s-112.1 - http://flybase.org/reports/FBgn0266494 gene - - - s-112.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040266 Transpac\gag Transpac element gag http://flybase.org/reports/FBgn0040266 transposable_element_gene - - - Transpac\gag - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262553 Mod(GMroX1)163 - http://flybase.org/reports/FBgn0262553 gene - - - Mod(GMroX1)163 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264643 disjointed disjointed http://flybase.org/reports/FBgn0264643 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - "disjointed, Disjointed" - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0024432 Dlc90F Dynein light chain 90F http://flybase.org/reports/FBgn0024432 "FBgn0010833, FBgn0017467" protein_coding_gene "dynein light intermediate chain binding ; GO:0051959 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity dynein intermediate chain binding ; GO:0045505 | inferred from physical interaction with sw" spermatid development ; GO:0007286 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity retrograde axonal transport ; GO:0008090 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cytoplasmic dynein complex ; GO:0005868 | inferred from sequence or structural similarity with HGNC:11694 dynein complex ; GO:0030286 | inferred from direct assay dynein complex ; GO:0030286 | inferred from sequence or structural similarity "Dlc90F, TcTex-1, tctex-1, CG12363, Tctex-1, dtctex-1, bs35g12.y1, tctex, Tctex, l(3)04091, Tctex1, dlc90F" IPR005334:Tctex-1 CG12363 11-Aug-17 DroID_v2017_08 "Drer\dynlt1, Drer\si:dkey-148f10.4, Drer\dynlt3" - "Cele\dylt-1, Cele\dylt-3" Xtro\dynlt1 "Mmus\Dynlt1f, Mmus\Dynlt3, Mmus\Dynlt1b, Mmus\Dynlt1a, Mmus\Dynlt1c" "Hsap\DYNLT3, Hsap\DYNLT1" "male sterile,recessive,partially lethal - majority die,viable,male semi-sterile,male fertile,long lived,visible,body color defective" "spermatozoon,spermatid,spermatocyte,centrosomeExel6178),Nebenkern,trichogen cell,mesothoracic tergum" FBgn0060862 l(3)S047523 lethal (3) S047523 http://flybase.org/reports/FBgn0060862 gene - - - "0475/23, l(3)S047523" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0265457 CR44357 - http://flybase.org/reports/FBgn0265457 non_protein_coding_gene - - - CR44357 - CR44357 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028418 Lk Leucokinin http://flybase.org/reports/FBgn0028418 protein_coding_gene hormone activity ; GO:0005179 | non-traceable author statement neuropeptide hormone activity ; GO:0005184 | inferred from mutant phenotype diuretic hormone activity ; GO:0008613 | inferred from direct assay diuretic hormone activity ; GO:0008613 | non-traceable author statement negative regulation of feeding behavior ; GO:2000252 | inferred from mutant phenotype body fluid secretion ; GO:0007589 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement positive regulation of cytosolic calcium ion concentration ; GO:0007204 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "DLK, LK, pp, CG13480, Drm-KIN, leucokinin, leukokinin, Lk, Leuk, lk, Leucokinin, LCK" - CG13480 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000861 fs(1)M55 female sterile (1) M55 http://flybase.org/reports/FBgn0000861 - gene - - - fs(1)M55 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0043997 Su(rst)C94 Su(rst)C94 http://flybase.org/reports/FBgn0043997 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C94, Su(rst)C94" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0040607 CG14244 - http://flybase.org/reports/FBgn0040607 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14244 IPR002557:Chitin binding domain CG14244 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035315 CG8960 - http://flybase.org/reports/FBgn0035315 protein_coding_gene - - - CG8960 - CG8960 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040333 brv3 brivido-3 http://flybase.org/reports/FBgn0040333 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR003915 calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 detection of mechanical stimulus ; GO:0050982 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity response to cold ; GO:0009409 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 "CG13762, EG:BACR7C10.7, CT33244, brv3" "IPR003915:Polycystic kidney disease type 2 protein, IPR013122:Polycystin cation channel, PKD1/PKD2" CG13762 11-Aug-17 DroID_v2017_08 "Drer\LOC100537993, Drer\pkd1a, Drer\pkd1b" - Cele\lov-1 Xtro\pkd1 "Mmus\Pkd1l1, Mmus\Pkdrej, Mmus\Pkd1, Mmus\Pkd1l3, Mmus\Pkd1l2" "Hsap\PKD1L1, Hsap\PKD2L1, Hsap\PKDREJ, Hsap\PKD1L3" "cold stress response defective,viable" FBgn0263509 CR43498 - http://flybase.org/reports/FBgn0263509 non_protein_coding_gene - - - CR43498 - CR43498 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086082 snoRNA:Or-CD11 - http://flybase.org/reports/FBgn0086082 snoRNA_gene - - - "snoRNA:Or-CD11, orphan CD11, CR34711, Or-CD11" - CR34711 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052820 CG32820 - http://flybase.org/reports/FBgn0052820 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with SGD_LOCUS:SPC110; SGD:S000002764 microtubule nucleation ; GO:0007020 | inferred from sequence or structural similarity with SGD_LOCUS:SPC110; SGD:S000002764 flagellated sperm motility ; GO:0030317 | inferred from sequence or structural similarity with MGD:Tekt3; MGI:MGI:1918312 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGD:Tekt3; MGI:MGI:1918312 CG32820 IPR000435:Tektin CG32820 11-Aug-17 DroID_v2017_08 "Drer\tekt3, Drer\tekt2, Drer\tekt1, Drer\tekt4" - Cele\R02E12.4 "Xtro\tekt3, Xtro\tekt1, Xtro\tekt4, Xtro\tekt2" "Mmus\Tekt1, Mmus\Tekt2, Mmus\Tekt4, Mmus\Tekt3, Mmus\Tekt5" "Hsap\TEKT4, Hsap\TEKT1, Hsap\TEKT3, Hsap\TEKT5, Hsap\TEKT2" FBgn0084167 LA00508 LA00508 http://flybase.net/reports/FBgn0084167.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0014026 RpL7A Ribosomal protein L7A http://flybase.org/reports/FBgn0014026 - protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 centrosome organization ; GO:0051297 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay "L7a, L7A, Surf3/rpL7a, Surf-3/rpL7a, CG3314, RpL7A, Rp L7A, RpL7a, RPL7a" "IPR018492:Ribosomal protein L7Ae/L8/Nhp2 family, IPR001921:Ribosomal protein L7A/L8, IPR004037:Ribosomal protein L7Ae conserved site, IPR004038:Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR029064:50S ribosomal protein L30e-like" CG3314 11-Aug-17 DroID_v2017_08 "Drer\rpl7a, Drer\zgc:153325" "Scer\RPL8A, Scer\RPL8B" "Cele\Y73B3A.18, Cele\rpl-7A" Xtro\rpl7a Mmus\Rpl7a Hsap\RPL7A embryonic stage -- adult stage "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC18709 IEK -2.402057537 -0.552404103 1.555604982 -2.805914739 0.916620787 3.82610895 FBgn0028932 CG16890 - http://flybase.org/reports/FBgn0028932 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BG:DS00797.4, CG16890" IPR019129:Folate-sensitive fragile site protein Fra10Ac1 CG16890 11-Aug-17 DroID_v2017_08 Drer\fra10ac1 - "Cele\C08H9.16, Cele\F26C11.1" Xtro\fra10ac1 Mmus\Fra10ac1 Hsap\FRA10AC1 "viable,fertile" DRSC01890 K 0.025850593 -0.454425889 -1.007377534 0.112200837 -0.117288693 2.097772151 FBgn0010064 M(2)38k M(2)38k http://flybase.org/reports/FBgn0010064 - gene - - - "M(2)[38k4], M(2)38k" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,visible" macrochaeta FBgn0086320 JR107 - http://flybase.org/reports/FBgn0086320 gene - - - JR107 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0029021 l(3)77CDa lethal (3) 77CDa http://flybase.org/reports/FBgn0029021 gene - - - l(3)77CDa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,wild-type" FBgn0005103 gusA gustatory A http://flybase.org/reports/FBgn0005103 - gene molecular_function ; GO:0003674 | no biological data available larval feeding behavior ; GO:0030536 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gusA - - 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,cold sensitive" FBgn0028615 l(2)W10 lethal (2) W10 http://flybase.org/reports/FBgn0028615 gene - - - "l(2R)W10, l(2)W10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040695 CG14976 - http://flybase.org/reports/FBgn0040695 protein_coding_gene - - - CG14976 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267483 CR45833 - http://flybase.org/reports/FBgn0267483 non_protein_coding_gene - - - CR45833 - CR45833 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051189 CG31189 - http://flybase.org/reports/FBgn0051189 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CG7096, CG31189, CG7096-C" IPR010562:Haemolymph juvenile hormone binding CG31189 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263558 mir-4980 mir-4980 stem loop http://flybase.org/reports/FBgn0263558 miRNA_gene - - - "mir-4980, dme-mir-4980, CR43543" - CR43543 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014965 gypsy\gag gypsy element gag http://flybase.org/reports/FBgn0014965 - transposable_element_gene - - - "ORF1, GAG, gypsy\gag, gag, Gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037406 Osi1 Osiris 1 http://flybase.org/reports/FBgn0037406 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi1, CG15585, osi1" IPR012464:Protein of unknown function DUF1676 CG15585 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011094 l(1)Q54 lethal (1) Q54 http://flybase.org/reports/FBgn0011094 FBgn0010210 gene - - - l(1)Q54 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035021 CG4622 - http://flybase.org/reports/FBgn0035021 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4622, ZCHC8, dZcchc8, Itp" "IPR001878:Zinc finger, CCHC-type, IPR006568:PSP, proline-rich" CG4622 11-Aug-17 DroID_v2017_08 Drer\zcchc8 - "Cele\Y34D9A.7, Cele\ZK632.11" Xtro\zcchc8 Mmus\Zcchc8 Hsap\ZCCHC8 "viable,fertile" FBgn0013325 RpL11 Ribosomal protein L11 http://flybase.org/reports/FBgn0013325 "FBgn0021801, FBgn0062462" protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Fmr1 "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002132, InterPro:IPR020929 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000242048" cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "RpL11, DL11, L11, l(2)k16914, EST A, CG7726, BcDNA:LD17235, RPL11, Rp L11, chr2R:14957112..14957299" "IPR002132:Ribosomal protein L5, IPR020929:Ribosomal protein L5, conserved site, IPR022803:Ribosomal protein L5 domain, IPR031309:Ribosomal protein L5, C-terminal, IPR031310:Ribosomal protein L5, N-terminal" CG7726 11-Aug-17 DroID_v2017_08 Drer\rpl11 "Scer\RPL11B, Scer\RPL11A, Scer\MRPL7" "Cele\rpl-11.2, Cele\rpl-11.1" Xtro\rpl11 "Mmus\Rpl11, Mmus\Gm5093" Hsap\RPL11 embryonic stage -- adult stage "lethal,recessive" DRSC07537 IEK -2.489937133 -2.24200888 1.791292245 -3.948174523 3.608686076 2.673291962 FBgn0037071 CG7632 - http://flybase.org/reports/FBgn0037071 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7632 "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG7632 11-Aug-17 DroID_v2017_08 Drer\serhl - "Cele\abhd-5.2, Cele\W01A11.1, Cele\abhd-5.1" "Xtro\serhl2, Xtro\serhl" Mmus\Serhl Hsap\SERHL2 viable FBgn0003938 snRNA:U5:63BC small nuclear RNA U5 at 63A http://flybase.org/reports/FBgn0003938 FBgn0003932 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-63BC, snRNA[[3]], K2, dU5, snRNA:U5:63A, snRNA:U5, snRNA4, snRNA3, U5snRNA63A, CR32908, U5snRNA, snRNA:U5:63BC, U5:63BC, U5 snRNA, U5 snRNA 63BC, 63B U5, chr3L:3074339..3074497" - CR32908 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034871 CG3906 - http://flybase.org/reports/FBgn0034871 protein_coding_gene - - - CG3906 IPR010629:Insect allergen-related CG3906 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0263774 CG43691 - http://flybase.org/reports/FBgn0263774 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43691, CG17049, CG17050" - CG43691 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035501 CG1299 - http://flybase.org/reports/FBgn0035501 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP18, c-SP18, CG1299" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG1299 11-Aug-17 DroID_v2017_08 "Drer\zgc:112285, Drer\ctrl, Drer\ctrb1, Drer\ela2l, Drer\zgc:112368, Drer\zgc:112302, Drer\zgc:92745, Drer\zgc:154142, Drer\si:dkey-238d18.3, Drer\zgc:92041, Drer\zgc:171592, Drer\ela2, Drer\zgc:112160, Drer\ela3l, Drer\zgc:92511, Drer\st14b, Drer\LOC562139, Drer\si:dkey-57c15.4" - - "Xtro\ctrb1, Xtro\cela2a, Xtro\ctrb2, Xtro\LOC100135144, Xtro\cela3a" "Mmus\Ctrb1, Mmus\Ctrc, Mmus\Cela3a, Mmus\Cela1, Mmus\Cela2a, Mmus\Cela3b, Mmus\Ctrl" "Hsap\CELA3A, Hsap\CTRB2, Hsap\CELA1, Hsap\CELA2A, Hsap\CTRC, Hsap\CELA2B, Hsap\PRSS12, Hsap\CTRB1, Hsap\CELA3B, Hsap\CTRL" viable FBgn0260810 EP3-1789 - http://flybase.org/reports/FBgn0260810 gene - - - EP3-1789 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001532 l(1)11Fb lethal (1) 11Fb http://flybase.org/reports/FBgn0001532 - gene - - - l(1)11Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0032289 CG6431 - http://flybase.org/reports/FBgn0032289 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 - - "CG6431, chr2L_10724193_10724543.0" "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR029058:Alpha/Beta hydrolase fold" CG6431 11-Aug-17 DroID_v2017_08 "Drer\lipg, Drer\pla1a, Drer\LOC101884800, Drer\lipib, Drer\lpl, Drer\lipca, Drer\LOC100331214, Drer\lipia" - - "Xtro\lpl, Xtro\lipg" "Mmus\Pnliprp1, Mmus\Pla1a, Mmus\Lipc, Mmus\Pnliprp2, Mmus\Liph, Mmus\Pnlip, Mmus\Lipi, Mmus\Lpl, Mmus\Lipg" "Hsap\PNLIPRP1, Hsap\PNLIPRP3, Hsap\LPL, Hsap\PLA1A, Hsap\LIPC, Hsap\LIPH, Hsap\PNLIPRP2, Hsap\LIPG, Hsap\PNLIP, Hsap\LIPI" viable FBgn0029890 CG4095 - http://flybase.org/reports/FBgn0029890 protein_coding_gene fumarate hydratase activity ; GO:0004333 | inferred from sequence or structural similarity with UniProtKB:P07954 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P07954 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 fumarate metabolic process ; GO:0006106 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle enzyme complex ; GO:0045239 | inferred from electronic annotation with InterPro:IPR005677 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000154501 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P07954 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P07954 CG4095 "IPR000362:Fumarate lyase family, IPR005677:Fumarate hydratase, class II, IPR008948:L-Aspartase-like, IPR024083:Fumarase/histidase, N-terminal, IPR018951:Fumarase C, C-terminal, IPR020557:Fumarate lyase, conserved site, IPR022761:Fumarate lyase, N-terminal" CG4095 11-Aug-17 DroID_v2017_08 "Drer\fh, Drer\LOC100535417" Scer\FUM1 Cele\fum-1 - Mmus\Fh1 Hsap\FH viable FBgn0260361 GSd431 - http://flybase.org/reports/FBgn0260361 gene - - - GSd431 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0010411 RpS18 Ribosomal protein S18 http://flybase.org/reports/FBgn0010411 "FBgn0014916, FBgn0025222, FBgn0062939" protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001892, InterPro:IPR018269 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001892, InterPro:IPR018269 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001892, InterPro:IPR018269 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome biogenesis ; GO:0042254 | inferred from biological aspect of ancestor with PANTHER:PTN000093238" nuclear chromosome ; GO:0000228 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with UniProtKB:P62269 nucleolus ; GO:0005730 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "S18, rpS18, B, anon-EST:fe2D3, anon-EST:Posey27, CG8900, BcDNA:RH43343, anon-56Fa, RpS18, Rps18, RS18_DROME, M(2)56F" "IPR018269:Ribosomal protein S13, conserved site, IPR001892:Ribosomal protein S13, IPR010979:Ribosomal protein S13-like, H2TH, IPR027437:30s ribosomal protein S13, C-terminal" CG8900 11-Aug-17 DroID_v2017_08 Drer\rps18 "Scer\RPS18B, Scer\RPS18A, Scer\SWS2" Cele\rps-18 Xtro\rps18 Mmus\Rps18 Hsap\RPS18 embryonic stage -- adult stage "lethal,viable,female fertile,female sterile" DRSC07540 IEK -1.688397032 -1.147814398 -2.981956834 -3.962467269 1.842357222 4.272608323 FBgn0014899 anon-10Af anon-10Af http://flybase.org/reports/FBgn0014899 - gene - - - anon-10Af - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040568 CG12331 - http://flybase.org/reports/FBgn0040568 protein_coding_gene - - - CG12331 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036102 CG12523 - http://flybase.org/reports/FBgn0036102 protein_coding_gene - - - "BcDNA:RE74758, CG12523" IPR031903:Domain of unknown function DUF4766 CG12523 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" DRSC09895 K 0.047105887 -0.143025395 -0.00241957 0.091430416 3.05753048 1.03766784 FBgn0001556 l(1)19Ca lethal (1) 19Ca http://flybase.org/reports/FBgn0001556 - gene - - - "17-457, 17-238, l(1)19Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0001797 l(1)Mb46 lethal (1) Mb46 http://flybase.org/reports/FBgn0001797 - gene - - - l(1)Mb46 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031051 Ranbp21 Ranbp21 http://flybase.org/reports/FBgn0031051 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001494 - "CG12234, Exp5, RanBP21, Ranbp21, dmExp5, Exp-5" "IPR001494:Importin-beta, N-terminal domain, IPR013598:Exportin-1/Importin-beta-like, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG12234 11-Aug-17 DroID_v2017_08 "Drer\xpo6, Drer\xpo1b, Drer\xpo1a, Drer\xpo5" "Scer\MSN5, Scer\CRM1" - "Xtro\exd3, Xtro\xpo6, Xtro\xpo5, Xtro\xpo1" "Mmus\Xpo5, Mmus\Xpo1, Mmus\Xpo6" "Hsap\XPO1, Hsap\XPO6, Hsap\XPO5" "viable,visible" trichogen cell FBgn0010133 l(1)tsW4 lethal (1) tsW4 http://flybase.org/reports/FBgn0010133 - gene - - - l(1)tsW4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0029580 CG14778 - http://flybase.org/reports/FBgn0029580 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 CG14778 IPR007248:Mpv17/PMP22 CG14778 11-Aug-17 DroID_v2017_08 "Drer\pxmp2, Drer\mpv17, Drer\mpv17l2, Drer\si:dkeyp-72e1.7, Drer\si:ch211-120k19.1" "Scer\YOR292C, Scer\SYM1" - "Xtro\mpv17l2, Xtro\pxmp2" "Mmus\Pxmp2, Mmus\Mpv17l, Mmus\Mpv17l2, Mmus\Mpv17" "Hsap\MPV17L, Hsap\MPV17, Hsap\MPV17L2, Hsap\PXMP2" FBgn0039751 CG1983 - http://flybase.org/reports/FBgn0039751 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from biological aspect of ancestor with PANTHER:PTN000015833 biological_process ; GO:0008150 | no biological data available intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000015833 CG1983 "IPR001608:Alanine racemase, N-terminal, IPR011078:COG0325 protein family, IPR029066:PLP-binding barrel" CG1983 11-Aug-17 DroID_v2017_08 Drer\prosc Scer\YBL036C "Cele\F09E5.8, Cele\F09E5.7" Xtro\prosc Mmus\Prosc Hsap\PROSC "viable,visible" trichogen cell FBgn0019815 eve::ftz::Mmus\En1 eve::ftz::Mmus\En1 http://flybase.org/reports/FBgn0019815 - engineered_fusion_gene - - - "eve::ftz::Mus\En1, eve::ftz::Mmus\En1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032363 Dlg5 Discs large 5 http://flybase.org/reports/FBgn0032363 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype apical part of cell ; GO:0045177 | inferred from direct assay "LD32687, CG6509, Dlg5, DLG5, dlg5" "IPR001478:PDZ domain, IPR008144:Guanylate kinase-like domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG6509 11-Aug-17 DroID_v2017_08 "Drer\dlg1, Drer\inadl, Drer\LOC100534780, Drer\grip2b, Drer\dlg3, Drer\dlg4b, Drer\dlg5b.1, Drer\si:dkey-92i15.4, Drer\dlg4, Drer\lnx1, Drer\pdzd7b, Drer\LOC100537443, Drer\card11, Drer\grip1, Drer\grid2ipa, Drer\dlg5a, Drer\il16, Drer\pard3bb, Drer\slc9a3r1" - Cele\magu-4 "Xtro\card14, Xtro\dlg4, Xtro\lnx1, Xtro\dlg1, Xtro\grip1, Xtro\dlg5, Xtro\grid2ip, Xtro\grip2" "Mmus\Ush1c, Mmus\Pdzd2, Mmus\Pdzd11, Mmus\Dlg2, Mmus\Dlg4, Mmus\Mpdz, Mmus\Dlg3, Mmus\Il16, Mmus\Dlg1, Mmus\Pdzph1, Mmus\Card14, Mmus\Lnx1, Mmus\Dlg5, Mmus\Patj, Mmus\Grid2ip, Mmus\Grasp, Mmus\Card10, Mmus\Grip1, Mmus\Grip2" "Hsap\DLG4, Hsap\DLG3, Hsap\DLG1, Hsap\GRASP, Hsap\FRMPD2, Hsap\USH1C, Hsap\IL16, Hsap\GRIP1, Hsap\GRID2IP, Hsap\LNX1, Hsap\DLG2, Hsap\PARD3B, Hsap\PDZD2, Hsap\CARD10, Hsap\MPDZ, Hsap\CARD14, Hsap\PATJ, Hsap\DLG5" "viable,visible" "border follicle cell,chaeta,supernumerary,mesothoracic tergum" DRSC02964 K -0.098174318 0.473062568 -0.917604602 0.780943502 0.622059393 1.846124625 FBgn0003424 slgB sluggish B http://flybase.org/reports/FBgn0003424 - gene - - - slgB - - 11-Aug-17 DroID_v2017_08 - - - - - - "phototaxis defective,male,female,mating defective,courtship behavior defective,behavior defective" FBgn0001512 l(1)10Ff lethal (1) 10Ff http://flybase.org/reports/FBgn0001512 - gene - - - l(1)10Ff - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040678 CG15586 - http://flybase.org/reports/FBgn0040678 protein_coding_gene - - - CG15586 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042133 CG18810 - http://flybase.org/reports/FBgn0042133 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 Golgi apparatus ; GO:0005794 | inferred from direct assay CG18810 "IPR001594:Palmitoyltransferase, DHHC domain" CG18810 11-Aug-17 DroID_v2017_08 "Drer\zgc:77880, Drer\zdhhc12b, Drer\zdhhc12a, Drer\zdhhc24, Drer\zdhhc23b, Drer\zdhhc3a, Drer\zdhhc22, Drer\LOC100334198, Drer\zdhhc8b, Drer\zdhhc5b, Drer\zdhhc18a, Drer\zdhhc14, Drer\zdhhc7, Drer\zdhhc20a, Drer\zdhhc5a, Drer\zdhhc23a, Drer\zdhhc20b, Drer\zdhhc21, Drer\zdhhc3b, Drer\zdhhc9, Drer\zdhhc1" "Scer\PFA5, Scer\ERF2" "Cele\dhhc-1, Cele\dhhc-12, Cele\dhhc-9, Cele\dhhc-10" "Xtro\zdhhc3, Xtro\zdhhc21, Xtro\zdhhc9, Xtro\zdhhc7, Xtro\zdhhc24, Xtro\dnz1, Xtro\zdhhc1, Xtro\zdhhc12, Xtro\zdhhc8, Xtro\zdhhc14" "Mmus\Zdhhc23, Mmus\Zdhhc25, Mmus\Zdhhc7, Mmus\Zdhhc18, Mmus\Zdhhc11, Mmus\Zdhhc14, Mmus\Zdhhc24, Mmus\Zdhhc9, Mmus\Zdhhc3, Mmus\Zdhhc20, Mmus\Zdhhc5, Mmus\Zdhhc8, Mmus\Zdhhc21, Mmus\Zdhhc22, Mmus\Zdhhc12, Mmus\Zdhhc1, Mmus\Zdhhc19" "Hsap\ZDHHC5, Hsap\ZDHHC9, Hsap\ZDHHC20, Hsap\ZDHHC11, Hsap\ZDHHC22, Hsap\ZDHHC18, Hsap\ZDHHC24, Hsap\ZDHHC19, Hsap\ZDHHC23, Hsap\ZDHHC14, Hsap\ZDHHC12, Hsap\ZDHHC1, Hsap\ZDHHC21, Hsap\ZDHHC7, Hsap\ZDHHC3, Hsap\ZDHHC8" viable FBgn0082958 snoRNA:Psi28S-3405c snoRNA:Psi28S-3405c http://flybase.org/reports/FBgn0082958 snoRNA_gene - - - "snoRNA:Psi28S-3405c, psi28s-3405c, CR34621, chr3R:24427860..24427959" - CR34621 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030411 CG2540 - http://flybase.org/reports/FBgn0030411 protein_coding_gene gamma-glutamylcyclotransferase activity ; GO:0003839 | inferred from biological aspect of ancestor with PANTHER:PTN001742855 glutathione catabolic process ; GO:0006751 | inferred from biological aspect of ancestor with PANTHER:PTN001742855 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001742855 CG2540 "IPR006840:Glutathione-specific gamma-glutamylcyclotransferase, IPR013024:Gamma-glutamyl cyclotransferase-like" CG2540 11-Aug-17 DroID_v2017_08 "Drer\chac1, Drer\chac2" Scer\GCG1 Cele\F22F7.7 Xtro\chac2 "Mmus\Chac2, Mmus\Chac1" "Hsap\CHAC2, Hsap\CHAC1" viable DRSC19856 K 0.370326627 0.461557943 0.378474815 0.286391636 -1.596268165 -0.210272847 FBgn0033543 CG12338 - http://flybase.org/reports/FBgn0033543 protein_coding_gene "D-amino-acid oxidase activity ; GO:0003884 | inferred from electronic annotation with InterPro:IPR006181, InterPro:IPR023209 FAD binding ; GO:0071949 | inferred from electronic annotation with InterPro:IPR023209" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR006181, InterPro:IPR023753 D-amino acid metabolic process ; GO:0046416 | inferred from electronic annotation with InterPro:IPR023209" peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:2671 inferred from sequence model CG12338 "IPR006076:FAD dependent oxidoreductase, IPR006181:D-amino acid oxidase, conserved site, IPR023209:D-amino-acid oxidase" CG12338 11-Aug-17 DroID_v2017_08 "Drer\dao.2, Drer\dao.3, Drer\dao.1, Drer\zgc:172341" - "Cele\daao-1, Cele\ddo-1, Cele\ddo-3, Cele\ddo-2" "Xtro\ddo, Xtro\dao" "Mmus\Dao, Mmus\Ddo" "Hsap\DDO, Hsap\DAO, Hsap\METTL24" "viable,fertile" FBgn0004756 l(3)89Bi lethal (3) 89Bi http://flybase.org/reports/FBgn0004756 - gene - - - l(3)89Bi - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028071 l(3)S090001 lethal (3) S090001 http://flybase.org/reports/FBgn0028071 gene - - - "0900/01, l(3)S090001" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005114 l(1)272-13 lethal (1) 272-13 http://flybase.org/reports/FBgn0005114 - gene - - - l(1)272-13 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035151 CG17129 - http://flybase.org/reports/FBgn0035151 protein_coding_gene - - - CG17129 - CG17129 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0250862 CG42237 - http://flybase.org/reports/FBgn0250862 protein_coding_gene phospholipase A2 activity ; GO:0004623 | inferred from electronic annotation with InterPro:IPR016090 phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090 - "C133, CG42237, CG4346, PLA2" "IPR016090:Phospholipase A2 domain, IPR033113:Phospholipase A2, histidine active site" CG42237 11-Aug-17 DroID_v2017_08 "Drer\LOC101885160, Drer\zgc:123275, Drer\proca1" - "Cele\F47C12.13, Cele\F36A4.5, Cele\F36A4.4, Cele\W04G3.12, Cele\F22E5.7, Cele\W04G3.10, Cele\F47C12.7, Cele\F36A4.3, Cele\F36A4.1, Cele\W04G3.7, Cele\W04G3.13" Xtro\proca1 "Mmus\Proca1, Mmus\Pla2g3" "Hsap\PROCA1, Hsap\PLA2G3" viable FBgn0034371 SP2637 SP2637 http://flybase.org/reports/FBgn0034371 protein_coding_gene protein-N-terminal asparagine amidohydrolase activity ; GO:0008418 | inferred from electronic annotation with InterPro:IPR026750 - - "dm-ntan1, BEST:GH24992, CG5473, SP2637" IPR026750:Protein N-terminal asparagine amidohydrolase CG5473 11-Aug-17 DroID_v2017_08 Drer\ntan1 - - Xtro\ntan1 Mmus\Ntan1 Hsap\NTAN1 "viable,fertile" FBgn0020559 anon-XII-F3 anon-XII-F3 http://flybase.org/reports/FBgn0020559 - gene - - - anon-XII-F3 - - 11-Aug-17 DroID_v2017_08 - - - - - - Bolwig nerve FBgn0014291 l(3)64Bb lethal (3) 64Bb http://flybase.org/reports/FBgn0014291 - gene - - - l(3)64Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263985 CR43734 - http://flybase.org/reports/FBgn0263985 pseudogene_attribute - - - CR43734 - CR43734 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261731 EC2364 - http://flybase.org/reports/FBgn0261731 gene - - - EC2364 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0262848 CR43212 - http://flybase.org/reports/FBgn0262848 pseudogene_attribute - - - "CR43212, noncoding_23159, noncoding_23161" - CR43212 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082348 HM415 HM415 http://flybase.org/reports/FBgn0082348 gene - - - HM415 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011479 l(3)neo46 lethal (3) neo46 http://flybase.org/reports/FBgn0011479 - gene - - - l(3)neo46 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261628 CG42711 - http://flybase.org/reports/FBgn0261628 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42711 - CG42711 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267552 CR45892 - http://flybase.org/reports/FBgn0267552 non_protein_coding_gene - - - CR45892 - CR45892 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259368 EP-575 - http://flybase.org/reports/FBgn0259368 gene - - - EP-575 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0260076 2L4744 - http://flybase.org/reports/FBgn0260076 gene - - - 2L4744 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0002884 mus109 mutagen-sensitive 109 http://flybase.org/reports/FBgn0002884 - gene - - - "mus107, mus-109, mus(1)107, mus(1)109, l(1)9Aa, l(1)19-65, mus109" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,mitotic cell cycle defective,recessive,lethal,radiation sensitive,female sterile,lethal - all die before end of larval stage,some die during larval stage" "mitosis & nuclear chromosome,imaginal disc,cell cycle" FBgn0052493 tRNA:Gln-TTG-2-1 transfer RNA:Glutamine-TTG 2-1 http://flybase.org/reports/FBgn0052493 tRNA_gene CAA codon-amino acid adaptor activity ; GO:0033427 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033427 cytosol ; GO:0005829 | inferred by curator from GO:0033427 "AE002566.trna6-GlnTTG, tRNA:Q:TTG:AE002566, CR32493, chrX.trna26-GlnTTG, tRNA:Gln-TTG-2-1, tRNA:CR32493, tRNA-Gln-TTG-2-1, CAA" - CR32493 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034464 CG11018 - http://flybase.org/reports/FBgn0034464 protein_coding_gene - - - "anon-WO0140519.121, CG11018" - CG11018 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC28771 K -0.146720555 0.278794802 0.192827345 -0.530770145 -1.627485798 0.085867644 FBgn0002251 l(3)68Ec lethal (3) 68Ec http://flybase.org/reports/FBgn0002251 - gene - - - "rsg13, l(3)rsg13, l(3)68Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0044127 E(rst)B203 E(rst)B203 http://flybase.org/reports/FBgn0044127 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B203, E(rst)B203" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "eye,cone cell,secondary pigment cell,ectopic,tertiary pigment cell" FBgn0002619 M(3)82BC Minute (3) 82BC http://flybase.org/reports/FBgn0002619 - gene - - - "M, M(3)S39, M(3)82BC" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible" macrochaeta FBgn0277420 l(3)psg23 - http://flybase.org/reports/FBgn0277420 gene - - - "l(3)psg23, psg23" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002669 mat(2)ea-F maternal effect early arrest F http://flybase.org/reports/FBgn0002669 - gene - - - "mat(2)earlyRL4, mat(2)ea-F" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0016676 Mab11B5 Monoclonal antibody 11B5 http://flybase.org/reports/FBgn0016676 - gene - - - Mab11B5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266649 CR45156 - http://flybase.org/reports/FBgn0266649 non_protein_coding_gene - - - CR45156 - CR45156 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033061 SmydA-5 "SET and MYND domain containing, arthropod-specific, member 5" http://flybase.org/reports/FBgn0033061 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 - "SmydA-5, CG14590" "IPR001214:SET domain, IPR002893:Zinc finger, MYND-type" CG14590 11-Aug-17 DroID_v2017_08 "Drer\smyd2b, Drer\smyd3, Drer\smyd4, Drer\smyd1a, Drer\smyd2a, Drer\smyd1b" "Scer\SET6, Scer\SET5" "Cele\set-18, Cele\set-10, Cele\set-14" "Xtro\smyd4, Xtro\smyd1, Xtro\smyd5" "Mmus\Smyd4, Mmus\Smyd3, Mmus\Zmynd15, Mmus\Smyd1, Mmus\Ankmy2, Mmus\Smyd2, Mmus\Smyd5" "Hsap\SMYD1, Hsap\ZMYND15, Hsap\SMYD4, Hsap\SMYD5, Hsap\SMYD2, Hsap\SMYD3, Hsap\ANKMY2" viable FBgn0022758 Wmc4 Wee-Mik-Complementing 4 http://flybase.org/reports/FBgn0022758 - gene - - - "WMC4, Wmc4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061046 l(3)S023634 lethal (3) S023634 http://flybase.org/reports/FBgn0061046 gene - - - "0236/34, l(3)S023634" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0002846 msd(gl) modifier of sexual dimorphism of glass http://flybase.org/reports/FBgn0002846 - gene - - - msd(gl) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259546 B0472 - http://flybase.org/reports/FBgn0259546 gene - - - B0472 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,leg,unguis,wing,arista,mesothoracic tergum" FBgn0065498 l(2)SH1214 lethal (2) SH1214 http://flybase.org/reports/FBgn0065498 gene - - - "l(2)SH1214, l(2)SH2 1214" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032169 CG4709 - http://flybase.org/reports/FBgn0032169 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 sleep ; GO:0030431 | inferred from expression pattern - "CG4709, ZGPAT" "IPR000467:G-patch domain, IPR000571:Zinc finger, CCCH-type" CG4709 11-Aug-17 DroID_v2017_08 Drer\zgpat - Cele\zgpa-1 Xtro\zgpat "Mmus\Lime1, Mmus\Zgpat" Hsap\ZGPAT viable FBgn0259123 ponchik ponchik http://flybase.org/reports/FBgn0259123 gene - - - ponchik - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086032 snoRNA:Me28S-C437 - http://flybase.org/reports/FBgn0086032 snoRNA_gene - - - "snoRNA:Me28S-C437, Me28S-Cm437, CR34661" - CR34661 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013600 l(3)B48.1M3 lethal (3) B48.1M3 http://flybase.org/reports/FBgn0013600 - gene - - - l(3)B48.1M3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003643 Su(y[3P]) Suppressor of yellow-P http://flybase.org/reports/FBgn0003643 - gene - - - "su-y[31e], Su(y[3P])" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063928 GS2035 GS2035 http://flybase.org/reports/FBgn0063928 gene - - - GS2035 - - 11-Aug-17 DroID_v2017_08 - - - - - - long lived FBgn0065568 l(2)SH0973 lethal (2) SH0973 http://flybase.org/reports/FBgn0065568 gene - - - "l(2)SH0973, l(2)SH2 0973" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263623 CR43632 - http://flybase.org/reports/FBgn0263623 non_protein_coding_gene - - - CR43632 - CR43632 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020223 Chr1 Chloroform resistant 1 http://flybase.org/reports/FBgn0020223 - gene - - - Chr1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant" FBgn0033124 Tsp42Ec Tetraspanin 42Ec http://flybase.org/reports/FBgn0033124 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model "CG12847, Dm.Tsp42Ec, Tsp42Ec" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12847 11-Aug-17 DroID_v2017_08 Drer\cd63 - "Cele\tsp-1, Cele\tsp-7, Cele\tsp-3, Cele\tsp-14, Cele\tsp-2" Xtro\cd63 Mmus\Cd63 "Hsap\TSPAN19, Hsap\CD63" viable FBgn0036212 CG11597 - http://flybase.org/reports/FBgn0036212 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000002292 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype peptidyl-serine dephosphorylation ; GO:0070262 | inferred from sequence or structural similarity with SGD:S000002347 protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002347 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002292 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002292 protein phosphatase type 2A complex ; GO:0000159 | inferred from sequence or structural similarity with SGD:S000002292 "CG11597, PP4" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG11597 11-Aug-17 DroID_v2017_08 "Drer\ppp2ca, Drer\ppp2cb, Drer\zgc:56064, Drer\ppp4cb, Drer\ppp4ca" "Scer\PPH21, Scer\PPH22, Scer\PPG1, Scer\PPH3" "Cele\pph-4.1, Cele\pph-4.2, Cele\let-92" "Xtro\ppp2cb, Xtro\ppp4c, Xtro\ppp2ca" "Mmus\Ppp4c, Mmus\Ppp2ca, Mmus\Ppp2cb" "Hsap\PPP4C, Hsap\PPP2CB, Hsap\PPP2CA" "viable,visible" "chaeta,trichogen cell" FBgn0003274 RpLP2 Ribosomal protein LP2 http://flybase.org/reports/FBgn0003274 "FBgn0003736, FBgn0062859" protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay translational elongation ; GO:0006414 | inferred from electronic annotation with InterPro:IPR027534 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "RpP1, rpA1, RpA1, bs34h02.y1, Tp1, T1, CG4918, BcDNA:SD22208, RpLP2, LP2, RLA2_DROME, RplP2, chr2R:12101099..12101299" IPR027534:Ribosomal protein L12 family CG4918 11-Aug-17 DroID_v2017_08 "Drer\rplp2, Drer\rplp2l" "Scer\RPP2A, Scer\RPP2B" "Cele\rla-2, Cele\C37A2.7" "Xtro\rplp2, Xtro\LOC100135138" Mmus\Rplp2 Hsap\RPLP2 viable DRSC07539 IEK -1.768852739 -1.733591978 -4.094998839 -5.591663459 -0.22835269 1.966046873 FBgn0013710 mt:tRNA:Tyr-GTA mitochondrial transfer RNA:Tyrosine-GTA http://flybase.org/reports/FBgn0013710 FBgn0002867 tRNA_gene - - - "CR34066, tRNAtyr, tRNA[Tyr], mtdbD00006297, mt:tRNA:Tyr-GTA, mt:tRNA:Y" - CR34066 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003196 Raf-oncogene-2 Raf oncogene 2 http://flybase.org/reports/FBgn0003196 - gene - - - "Draf-2, raf2, Raf-oncogene-2, Raf2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023435 jew jewel http://flybase.org/reports/FBgn0023435 - gene - - - jew - - 11-Aug-17 DroID_v2017_08 - - - - - - visible pigment cell FBgn0037195 CG11226 - http://flybase.org/reports/FBgn0037195 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "BcDNA:AT16729, CG11226" - CG11226 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0065465 l(2)SH1344 lethal (2) SH1344 http://flybase.org/reports/FBgn0065465 gene - - - "l(2)SH1344, l(2)SH2 1344" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060291 snoRNA:U49:66Db snoRNA:U49:66Db http://flybase.org/reports/FBgn0060291 snoRNA_gene - - - "Dmel\U49b, U49b, CR32910, snoRNA:U49:66Db, Me28S-C3341(U49)" - CR32910 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262994 CR43302 - http://flybase.org/reports/FBgn0262994 non_protein_coding_gene - - - CR43302 - CR43302 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035970 CG4483 - http://flybase.org/reports/FBgn0035970 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG4483 "IPR001594:Palmitoyltransferase, DHHC domain" CG4483 11-Aug-17 DroID_v2017_08 Drer\zdhhc6 "Scer\ERF2, Scer\PFA4, Scer\PFA3, Scer\SWF1" "Cele\dhhc-5, Cele\dhhc-6" Xtro\zdhhc6 Mmus\Zdhhc6 Hsap\ZDHHC6 viable FBgn0039758 CG9737 - http://flybase.org/reports/FBgn0039758 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 phagocytosis ; GO:0006909 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model" - "CG9737, SP5, c-SP5" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG9737 11-Aug-17 DroID_v2017_08 - - "Cele\svh-1, Cele\try-3, Cele\try-1" - "Mmus\Klk1b11, Mmus\Klk1b21, Mmus\Klk1b24, Mmus\Klk1b4, Mmus\Klk1, Mmus\Klk1b5, Mmus\Klk1b1, Mmus\F11, Mmus\Klk1b16, Mmus\Klkb1, Mmus\Klk11, Mmus\Klk1b26, Mmus\Klk1b27, Mmus\Klk1b22, Mmus\Klk1b3, Mmus\Egfbp2, Mmus\Klk1b8, Mmus\Klk1b9" "Hsap\KLK11, Hsap\KLK2, Hsap\KLK3, Hsap\KLK1, Hsap\KLKB1, Hsap\F11" viable FBgn0259607 B1116 - http://flybase.org/reports/FBgn0259607 gene - - - B1116 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,proboscis" FBgn0005281 M(3)d Minute (3) d http://flybase.org/reports/FBgn0005281 - gene - - - M(3)d - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020542 l(1)18DEc lethal (1) 18DEc http://flybase.org/reports/FBgn0020542 - gene - - - l(1)18DEc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023511 Edem1 "ER degradation enhancer, mannosidase alpha-like 1" http://flybase.org/reports/FBgn0023511 - protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001382 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571 | inferred from sequence model" glycoprotein ERAD pathway ; GO:0097466 | inferred from biological aspect of ancestor with PANTHER:PTN000201758 endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from genetic interaction with ninaE determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype N-glycan processing ; GO:0006491 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from genetic interaction with ninaE membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001382 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000201533 "EG:86E4.2, DM-pI, Edem1, EDEM1, CG3810, EG.86E4.2, edem1" IPR001382:Glycoside hydrolase family 47 CG3810 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-282j22.3, Drer\edem1, Drer\edem3, Drer\edem2" Scer\MNL1 "Cele\F10C2.5, Cele\C47E12.3, Cele\ZC506.1" "Xtro\edem1, Xtro\edem3, Xtro\edem2" "Mmus\Edem2, Mmus\Edem3, Mmus\Edem1" "Hsap\EDEM3, Hsap\EDEM2, Hsap\EDEM1" "viable,long lived,dominant,partially lethal - majority die,some die during pharate adult stage" FBgn0005764 l(1)TK411 lethal (1) TK411 http://flybase.org/reports/FBgn0005764 - gene - - - "l411, l(1)TK411" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0032701 CG10341 - http://flybase.org/reports/FBgn0032701 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:Q96HR8 pseudouridine synthesis ; GO:0001522 | inferred from electronic annotation with InterPro:IPR007504 ribosome biogenesis ; GO:0042254 | inferred from sequence or structural similarity with UniProtKB:Q96HR8 neurogenesis ; GO:0022008 | inferred from mutant phenotype small nucleolar ribonucleoprotein complex ; GO:0005732 | inferred from sequence or structural similarity with UniProtKB:Q96HR8 CG10341 "IPR007504:H/ACA ribonucleoprotein complex, subunit Gar1/Naf1, IPR009000:Translation protein, beta-barrel domain" CG10341 11-Aug-17 DroID_v2017_08 Drer\naf1 Scer\NAF1 Cele\F25H8.2 - Mmus\Naf1 Hsap\NAF1 "lethal,neuroanatomy defective" ganglion mother cell FBgn0260587 2L2436 - http://flybase.org/reports/FBgn0260587 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2436 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0040738 CG14504 - http://flybase.org/reports/FBgn0040738 protein_coding_gene - - - CG14504 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085793 CR41510 - http://flybase.org/reports/FBgn0085793 non_protein_coding_gene - - - CR41510 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000988 mama maternal metaphase arrest http://flybase.org/reports/FBgn0000988 - gene - - - "mat(2)lto-DF6, fs(2)ltoDF6, fs(2)lto5, fs(2)lo-A, mama" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,female sterile,mitotic cell cycle defective,male fertile,reduced" "oocyte,maternal effect,adult fat body,yolk,adult corpus allatum,pre-blastoderm embryo,female" FBgn0001405 l(1)3Ag lethal (1) 3Ag http://flybase.org/reports/FBgn0001405 - gene - - - "zw-13, zw13, l(1)zw13, ZW-13, l(1)3Ag" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" female reproductive system FBgn0014127 barr barren http://flybase.org/reports/FBgn0014127 - protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay DNA topoisomerase binding ; GO:0044547 | inferred from physical interaction with Top2 DNA topoisomerase (ATP-hydrolyzing) activator activity ; GO:0072587 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with ph-p morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement mitotic sister chromatid segregation ; GO:0000070 | traceable author statement mitotic sister chromatid separation ; GO:0051306 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype ectodermal digestive tract morphogenesis ; GO:0048567 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from biological aspect of ancestor with PANTHER:PTN000318716 tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay "chromatin ; GO:0000785 | inferred from direct assay condensin complex ; GO:0000796 | inferred from direct assay condensed chromosome ; GO:0000793 | inferred from direct assay nuclear condensin complex ; GO:0000799 | inferred from biological aspect of ancestor with PANTHER:PTN000318716 condensin complex ; GO:0000796 | non-traceable author statement chromosome, centromeric region ; GO:0000775 | inferred from direct assay condensin complex ; GO:0000796 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:1112" "barren, CAP-H, 38B.3, CG10726, barr, CG14684, Barr, Barren, Cap-H, dCap-H, CapH" IPR022816:Condensin complex subunit 2/barren CG10726 11-Aug-17 DroID_v2017_08 Drer\ncaph Scer\BRN1 - Xtro\ncaph Mmus\Ncaph Hsap\NCAPH embryonic stage | early

ubiquitous "viable,fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,suppressor of variegation,dominant,enhancer of variegation,non-enhancer of variegation,partially,wild-type,mitotic cell cycle defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "peripheral nervous system,neuron,presumptive embryonic/larval peripheral nervous system,multidendritic neuron,chordotonal organ,lateral,embryonic Malpighian tubule,embryonic/larval proventriculus,midgut constriction,embryonic head,embryonic/larval trachea,embryonic epidermis,embryonic/larval pharynx,mitotic cell cycle,chromosome,mitosis & nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell" DRSC03488 IE 2.922058063 0.268740856 2.419523358 -0.498801451 0.714604813 0.591708005 FBgn0039626 Slu7 Slu7 http://flybase.org/reports/FBgn0039626 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 pre-mRNA 3'-splice site binding ; GO:0030628 | inferred from sequence or structural similarity with UniProtKB:O95391 second spliceosomal transesterification activity ; GO:0000386 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000310059 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002495 mRNA 3'-splice site recognition ; GO:0000389 | inferred from sequence or structural similarity with UniProtKB:O95391" nuclear speck ; GO:0016607 | inferred from sequence or structural similarity with UniProtKB:O95391 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000002495 spliceosomal complex ; GO:0005681 | inferred from biological aspect of ancestor with PANTHER:PTN000310059 "Slu7, CG1420, SLU7" "IPR001878:Zinc finger, CCHC-type, IPR021715:Pre-mRNA splicing Prp18-interacting factor" CG1420 11-Aug-17 DroID_v2017_08 Drer\slu7 Scer\SLU7 Cele\K07C5.6 Xtro\slu7 Mmus\Slu7 Hsap\SLU7 lethal FBgn0051908 CG31908 - http://flybase.org/reports/FBgn0051908 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG8761, CG31908" "IPR024642:SUZ-C domain, IPR024771:SUZ domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG31908 11-Aug-17 DroID_v2017_08 Drer\szrd1 - - Xtro\szrd1 Mmus\Szrd1 Hsap\SZRD1 FBgn0070010 BG01353 BG01353 http://flybase.org/reports/FBgn0070010 gene - - - BG01353 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0039507 mrt martik http://flybase.org/reports/FBgn0039507 protein_coding_gene molecular_function ; GO:0003674 | no biological data available olfactory learning ; GO:0008355 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG3361, mrt" - CG3361 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,viable,fertile" FBgn0085624 CG41339 - http://flybase.org/reports/FBgn0085624 protein_coding_gene - - - CG41339 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029752 TrxT Thioredoxin T http://flybase.org/reports/FBgn0029752 protein_coding_gene "thioredoxin-disulfide reductase activity ; GO:0004791 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 oxidoreductase activity ; GO:0016491 | non-traceable author statement protein-disulfide reductase activity ; GO:0047134 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ; GO:0016671 | inferred from biological aspect of ancestor with PANTHER:PTN000047179" glycerol ether metabolic process ; GO:0006662 | inferred from electronic annotation with InterPro:IPR005746 cell redox homeostasis ; GO:0045454 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 oxidation-reduction process ; GO:0055114 | non-traceable author statement protein folding ; GO:0006457 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 Y chromosome ; GO:0000806 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 "TrxT, CG3315, DmTrxT, DmelTrxT, 3315" "IPR005746:Thioredoxin, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site" CG3315 11-Aug-17 DroID_v2017_08 "Drer\ahnak, Drer\zgc:56493, Drer\txn, Drer\txn2" "Scer\TRX1, Scer\TRX2, Scer\TRX3" "Cele\Y55F3AR.2, Cele\trx-4, Cele\trx-3, Cele\W01B11.6, Cele\trx-2, Cele\trx-1" "Xtro\ahnak, Xtro\txn, Xtro\nme9, Xtro\LOC100170420, Xtro\prx, Xtro\LOC100498224" "Mmus\Txn2, Mmus\Txndc2, Mmus\Ahnak2, Mmus\Txndc8, Mmus\Ahnak, Mmus\Nme8, Mmus\Txn1" "Hsap\TXN2, Hsap\TXN, Hsap\AHNAK2, Hsap\TXNDC8, Hsap\NME8, Hsap\AHNAK, Hsap\TXNDC2" "chemical resistant,long lived,viable" FBgn0024851 mus113 mus113 http://flybase.org/reports/FBgn0024851 - gene - - - mus113 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0025882 snoRNA:MeU6-A47 snoRNA:MeU6-A47 http://flybase.org/reports/FBgn0025882 FBgn0052519 snoRNA_gene - - - "mgU6-47 snoRNA, CR32519, snoRNA:MeU6-A47, MeU6-A47(Z30), snoRNA:Z30, mgU6-47, chrX:21197545..21197641" - CR32519 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003521 stb short bristle http://flybase.org/reports/FBgn0003521 - gene - - - stb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile" macrochaeta FBgn0267158 CR45598 - http://flybase.org/reports/FBgn0267158 non_protein_coding_gene - - - CR45598 - CR45598 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060867 l(3)S047214 lethal (3) S047214 http://flybase.org/reports/FBgn0060867 gene - - - "0472/14, l(3)S047214" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0261380 mRpL37 mitochondrial ribosomal protein L37 http://flybase.org/reports/FBgn0261380 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AW960439 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AW960439 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AW960439 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CG42632, MRP-L2, CG6547, mRpL2a, mRpL37, MRpL37" IPR010793:Ribosomal protein L37/S30 CG42632 11-Aug-17 DroID_v2017_08 Drer\mrpl37 - Cele\mrpl-37 Xtro\mrpl37 Mmus\Mrpl37 Hsap\MRPL37 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0005718 l(1)TK125 lethal (1) TK125 http://flybase.org/reports/FBgn0005718 - gene - - - "l125, l(1)TK125" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0014011 Rac2 Rac2 http://flybase.org/reports/FBgn0014011 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z7T0 inferred from physical interaction with UniProtKB:P48148 GTPase activity ; GO:0003924 | traceable author statement GTPase activity ; GO:0003924 | inferred from genetic interaction with cv-c protein kinase binding ; GO:0019901 | inferred from physical interaction with Pak3" "lamellipodium assembly ; GO:0030032 | inferred from mutant phenotype aggressive behavior ; GO:0002118 | inferred from mutant phenotype dorsal closure, elongation of leading edge cells ; GO:0007394 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | traceable author statement feeding behavior ; GO:0007631 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from genetic interaction with Rac1 phagocytosis ; GO:0006909 | inferred from mutant phenotype Rho protein signal transduction ; GO:0007266 | inferred from genetic interaction with Zir lateral inhibition ; GO:0046331 | inferred from mutant phenotype mating behavior ; GO:0007617 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from genetic interaction with Rac1, Mtl immune response-regulating cell surface receptor signaling pathway involved in phagocytosis ; GO:0002433 | inferred from direct assay dorsal closure ; GO:0007391 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with LIMK1 melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | traceable author statement tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from genetic interaction with Rac1 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype adherens junction maintenance ; GO:0034334 | inferred from genetic interaction with Rac1 dorsal closure ; GO:0007391 | traceable author statement dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from genetic interaction with Rac1 positive regulation of wound healing ; GO:0090303 | inferred from genetic interaction with Rac1, Mtl salivary gland morphogenesis ; GO:0007435 | inferred from genetic interaction with Rac1 hemocyte migration ; GO:0035099 | inferred from genetic interaction with Rac1" intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003578 "Rac2, Drac2, DmRAC2, Rac, rac2, Rac GTPase, D-Rac2, D-Rac 2, CG8556, DRac2, Rac-2, Drac1b, Rac1b, DRacB, RacB, P48554, Rac1" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR003578:Small GTPase superfamily, Rho type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8556 11-Aug-17 DroID_v2017_08 "Drer\rhoq, Drer\rhoab, Drer\rnd3b, Drer\rhoj, Drer\rhogc, Drer\rac3a, Drer\rhocb, Drer\si:ch211-133l11.10, Drer\rac1a, Drer\rhobtb2b, Drer\rhoac, Drer\rac1b, Drer\cdc42, Drer\rhov, Drer\rnd1a, Drer\rhogb, Drer\LOC100331257, Drer\rhoca, Drer\rhobtb2a, Drer\si:dkey-263f15.2, Drer\rhoua, Drer\rnd1b, Drer\rac1l, Drer\rhoh, Drer\LOC100537765, Drer\cdc42l2, Drer\rhof, Drer\rhoga, Drer\rac2, Drer\rhoaa, Drer\rac3b, Drer\rhobtb1, Drer\si:dkey-6b12.5, Drer\cdc42l, Drer\rhoub, Drer\rhogd, Drer\rnd2, Drer\rnd3a" "Scer\RHO2, Scer\RHO3, Scer\RHO4, Scer\RHO1, Scer\RHO5, Scer\CDC42" "Cele\ced-10, Cele\mig-2, Cele\cdc-42, Cele\Y71H2AM.12, Cele\rac-2" "Xtro\rnd3, Xtro\cdc42, Xtro\rhou, Xtro\rac2, Xtro\rhobtb1, Xtro\rhob, Xtro\rhobtb3, Xtro\rhoc, Xtro\rhov, Xtro\rhoj, Xtro\rhoa.2, Xtro\rhoa, Xtro\rhof, Xtro\rnd1, Xtro\rac1, Xtro\rhobtb2" "Mmus\Rhoj, Mmus\4930544G11Rik, Mmus\Rhou, Mmus\Rhoh, Mmus\Rhog, Mmus\Rhof, Mmus\Rnd3, Mmus\Rnd1, Mmus\Rhoc, Mmus\Rac2, Mmus\Rhoq, Mmus\Rhob, Mmus\Rhod, Mmus\Rhoa, Mmus\Rhov, Mmus\Rhobtb2, Mmus\Rac1, Mmus\Rnd2, Mmus\Cdc42, Mmus\Rac3, Mmus\Rhobtb1, Mmus\Rhobtb3" "Hsap\RHOQ, Hsap\RHOG, Hsap\RND2, Hsap\RHOV, Hsap\RND3, Hsap\RAC2, Hsap\RHOH, Hsap\RHOBTB1, Hsap\CDC42, Hsap\RHOBTB2, Hsap\RAC3, Hsap\RHOA, Hsap\RND1, Hsap\RHOB, Hsap\RHOC, Hsap\RAC1, Hsap\RHOD, Hsap\RHOBTB3, Hsap\RHOJ, Hsap\RHOU, Hsap\RHOF" " embryonic stage | pre-blastoderm , embryonic stage | stage 12-13 , embryonic stage , embryonic stage | stage 5-6 , embryonic stage | >stage 13 , embryonic stage | stage 11-13 , embryonic stage -- adult stage " " organism | ubiquitous

, visceral mesoderm

, organism | pair rule

,

ubiquitous , head mesoderm

, somatic mesoderm

" "visible,immune response defective,viable,neuroanatomy defective,feeding behavior defective,short lived,long lived,recessive,behavior defective,male limited,locomotor behavior defective,courtship behavior defective,neurophysiology defective,male fertile,cell shape defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "embryonic somatic muscle,embryonic pericardial cell,eye,ommatidium,wing,wing vein,mesoderm,embryonic myoblast,muscle founder cell,supernumerary,pericardial cell,peripheral glial cell,serotonergic neuron,plasmatocyte,lamellocyte,embryonic/larval hemocyte,retina,photoreceptor,pigment cell,chaeta,dorsal appendage,posterior" DRSC11262 I -0.146412449 -2.529934619 -0.305536688 -0.693342144 -0.593383139 0.239970457 FBgn0259846 Su(Ste):CR42415 Su(Ste):CR42415 http://flybase.org/reports/FBgn0259846 non_protein_coding_gene - - - "Su(Ste):CR42415, CR42415" - CR42415 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063491 GstE9 Glutathione S transferase E9 http://flybase.org/reports/FBgn0063491 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "Gst3-1, CT38753, CG17534, DmGSTE9, GST3-1, GstE9, GSTE9, E9, gste9" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17534 11-Aug-17 DroID_v2017_08 "Drer\vars, Drer\gstt1a, Drer\mars, Drer\eef1e1, Drer\gstr, Drer\eef1g, Drer\gstt2, Drer\gstt1b" "Scer\TEF4, Scer\YGR201C, Scer\URE2, Scer\GTT2, Scer\CAM1, Scer\GTT1" "Cele\gst-34, Cele\gst-44, Cele\gsto-3, Cele\gsto-2, Cele\gst-21, Cele\gst-29, Cele\gst-32" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Eef1e1, Mmus\Gstt4, Mmus\Eef1g, Mmus\Gstt2, Mmus\Gsto1, Mmus\Vars, Mmus\Gstt1, Mmus\Mars, Mmus\Gstt3" "Hsap\GSTT2, Hsap\VARS, Hsap\MARS, Hsap\GSTT2B, Hsap\EEF1G, Hsap\GSTO1, Hsap\GSTT1, Hsap\EEF1E1" viable FBgn0069306 X-72-7 X-72-7 http://flybase.org/reports/FBgn0069306 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-72-7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "filzkorper,cephalopharyngeal skeleton" FBgn0027779 VhaSFD Vacuolar H[+]-ATPase SFD subunit http://flybase.org/reports/FBgn0027779 - protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000075631" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR004908, InterPro:IPR011987 vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000075631 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181" "lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN000842131 plasma membrane ; GO:0005886 | inferred from direct assay vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD:S000006240 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from biological aspect of ancestor with PANTHER:PTN000075631" "vhaSFD, 144191_at, V-ATPase, CG17332, VhaSFD, ATP6V1H" "IPR004908:ATPase, V1 complex, subunit H, IPR011987:ATPase, V1 complex, subunit H, C-terminal, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG17332 11-Aug-17 DroID_v2017_08 Drer\atp6v1h Scer\VMA13 "Cele\vha-15, Cele\vha-18" Xtro\atp6v1h Mmus\Atp6v1h Hsap\ATP6V1H "viable,size defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,long lived,lethal - all die before end of pupal stage,some die during pupal stage" "eye disc,somatic clone,multivesicular body | larval stage | somatic clone,Malpighian tubule" FBgn0023068 l(1)20Ai lethal (1) 20Ai http://flybase.org/reports/FBgn0023068 - gene - - - "C2/44.1, l(1)20Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002559 lot lot http://flybase.org/reports/FBgn0002559 - gene - - - "lot-235, lot" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267032 CR45476 - http://flybase.org/reports/FBgn0267032 non_protein_coding_gene - - - CR45476 - CR45476 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003920 snRNA:U2:14B small nuclear RNA U2 at 14B http://flybase.org/reports/FBgn0003920 FBgn0003919 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay "U2, dU2, U2 snRNA, U2-14B, K6, snRNA:U2, U2snRNA14B, CR32913, U2snRNA, snRNA:U2:14B, U2:14B, 14B U2" - CR32913 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038371 Pbp45 PSEA-binding protein 45kD http://flybase.org/reports/FBgn0038371 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Pbp95 bent DNA binding ; GO:0003681 | inferred from direct assay snRNA transcription from RNA polymerase II promoter ; GO:0042795 | inferred from direct assay snRNA transcription from RNA polymerase III promoter ; GO:0042796 | inferred from direct assay protein-DNA complex assembly ; GO:0065004 | inferred from direct assay snRNA-activating protein complex ; GO:0019185 | inferred from physical interaction with Pbp95 snRNA-activating protein complex ; GO:0019185 | inferred from direct assay "Pbp45, DmSNAP43, DmPBP45, CG9597, DmPBP, DmSNAPc, SNAP43" "IPR019188:Small nuclear RNA activating complex (SNAPc), subunit SNAP43" CG9597 11-Aug-17 DroID_v2017_08 "Drer\snapc1a, Drer\snapc1b" - "Cele\snpc-1.3, Cele\snpc-1.1, Cele\snpc-1.2, Cele\R05F9.11" Xtro\snapc1 Mmus\Snapc1 Hsap\SNAPC1 "viable,visible" trichogen cell FBgn0060757 l(3)S063818 lethal (3) S063818 http://flybase.org/reports/FBgn0060757 gene - - - "0638/18, l(3)S063818" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065658 l(2)SH0718 lethal (2) SH0718 http://flybase.org/reports/FBgn0065658 gene - - - "l(2)SH0718, l(2)SH2 0718" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262612 CG43138 - http://flybase.org/reports/FBgn0262612 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43138 - CG43138 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002553 lix little isoxanthopterin http://flybase.org/reports/FBgn0002553 - gene dihydropterin oxidase activity ; GO:0004154 | inferred from mutant phenotype - - lix - - 11-Aug-17 DroID_v2017_08 - - - - - - wild-type testis pigment cell FBgn0065284 l(2)SH2023 lethal (2) SH2023 http://flybase.org/reports/FBgn0065284 gene - - - "l(2)SH2023, l(2)SH2 2023" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065159 l(3)SH045 lethal (3) SH045 http://flybase.org/reports/FBgn0065159 gene - - - "l(3)SH045, l(2)SH3 045" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020357 anon-28Cf anon-28Cf http://flybase.org/reports/FBgn0020357 - gene - - - "538, anon-28Cf" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016777 anon-77Ba anon-77Ba http://flybase.org/reports/FBgn0016777 - gene - - - "A, anon-77Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032193 CG5727 - http://flybase.org/reports/FBgn0032193 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "BcDNA:LD02427, CG5727" - CG5727 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003556 su(dx)r "suppressor of deltex, recessive" http://flybase.org/reports/FBgn0003556 - gene - - - "su[X]-dx, su(dx)r, su(dx)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060934 l(3)S041405 lethal (3) S041405 http://flybase.org/reports/FBgn0060934 gene - - - "0414/05, l(3)S041405" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266124 ghi ghiberti http://flybase.org/reports/FBgn0266124 protein_coding_gene "serine C-palmitoyltransferase activity ; GO:0004758 | inferred from sequence or structural similarity with HGNC:20361,HGNC:24045" meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype sphingolipid biosynthetic process ; GO:0030148 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype "serine C-palmitoyltransferase complex ; GO:0017059 | inferred from sequence or structural similarity with HGNC:20361,HGNC:24045" "ghi, fro, CG32038" - CG32038 11-Aug-17 DroID_v2017_08 - - Cele\R05G9.3 - - - FBgn0029710 CG3568 - http://flybase.org/reports/FBgn0029710 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3568 IPR032063:Protein of unknown function DUF4804 CG3568 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005156 l(2)G121 lethal (2) G121 http://flybase.org/reports/FBgn0005156 - gene - - - l(2)G121 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0042129 OS9 Olfactory-specific 9 http://flybase.org/reports/FBgn0042129 protein_coding_gene - sensory perception of smell ; GO:0007608 | inferred from expression pattern nucleus ; GO:0005634 | inferred from direct assay "CG18806, OS9" - CG18806 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264648 ivy ivy http://flybase.org/reports/FBgn0264648 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - ivy - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0259648 B1022 - http://flybase.org/reports/FBgn0259648 gene - - - B1022 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "submarginal cell,wing vein,anterior crossvein" FBgn0023117 anon-10Aq anon-10Aq http://flybase.org/reports/FBgn0023117 - gene - - - "9, anon-10Aq" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051637 CG31637 - http://flybase.org/reports/FBgn0051637 protein_coding_gene N-acetylglucosamine 6-O-sulfotransferase activity ; GO:0001517 | inferred from biological aspect of ancestor with PANTHER:PTN000842280 sulfur compound metabolic process ; GO:0006790 | inferred from biological aspect of ancestor with PANTHER:PTN001322541 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001322541 "CG9551, CG13765, anon-WO0118547.107, CG31637, d6ST1" "IPR000863:Sulfotransferase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG31637 11-Aug-17 DroID_v2017_08 "Drer\chst3b, Drer\chst2b, Drer\chst1, Drer\zgc:194879, Drer\chst7, Drer\chst2a, Drer\chst3a, Drer\si:ch73-62b13.1" - - "Xtro\chst3, Xtro\chst2, Xtro\chst6, Xtro\chst1, Xtro\chst7, Xtro\chst4" "Mmus\Chst1, Mmus\Chst7, Mmus\Chst5, Mmus\Chst2, Mmus\Chst3, Mmus\Chst4" "Hsap\CHST1, Hsap\CHST6, Hsap\CHST7, Hsap\CHST3, Hsap\CHST4, Hsap\CHST2, Hsap\CHST5" "viable,visible" trichogen cell DRSC03263 E -0.510386318 1.233864253 1.894499972 -0.401475802 -0.328418541 -0.165569235 FBgn0031320 CG5126 - http://flybase.org/reports/FBgn0031320 protein_coding_gene - - - CG5126 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG5126 11-Aug-17 DroID_v2017_08 - - "Cele\F59B1.8, Cele\H06H21.8" - - - "viable,fertile" FBgn0040382 CG5273 - http://flybase.org/reports/FBgn0040382 protein_coding_gene - regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype - "EG:BACR19J1.3, CG5273" IPR032086:Protein of unknown function DUF4813 CG5273 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,locomotor rhythm defective" FBgn0032609 CG13280 - http://flybase.org/reports/FBgn0032609 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR000683 - - CG13280 "IPR000683:Oxidoreductase, N-terminal, IPR016040:NAD(P)-binding domain" CG13280 11-Aug-17 DroID_v2017_08 "Drer\zgc:101723, Drer\dhdhl" "Scer\YMR315W, Scer\GAL80" - Xtro\dhdh Mmus\Dhdh Hsap\DHDH FBgn0261506 CG42654 - http://flybase.org/reports/FBgn0261506 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42654 - CG42654 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021769 nori-6 nori-6 http://flybase.org/reports/FBgn0021769 - gene - - - nori-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,heat sensitive" FBgn0037792 TAF1B TATA box-binding protein-associated factor RNA polymerase I subunit B http://flybase.org/reports/FBgn0037792 protein_coding_gene "RNA polymerase I CORE element sequence-specific DNA binding ; GO:0001164 | inferred from biological aspect of ancestor with PANTHER:PTN001586581 transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting ; GO:0001187 | inferred from biological aspect of ancestor with PANTHER:PTN001586581 transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting ; GO:0001187 | inferred from sequence or structural similarity with UniProtKB:Q53T94 RNA polymerase I CORE element sequence-specific DNA binding ; GO:0001164 | inferred from sequence or structural similarity with UniProtKB:Q53T94" positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter ; GO:1901838 | inferred from mutant phenotype RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript ; GO:0001189 | inferred from sequence or structural similarity with UniProtKB:Q53T94 RNA polymerase transcription factor SL1 complex ; GO:0005668 | inferred from direct assay RNA polymerase transcription factor SL1 complex ; GO:0005668 | inferred from biological aspect of ancestor with PANTHER:PTN001586581 RNA polymerase I core factor complex ; GO:0070860 | inferred from biological aspect of ancestor with PANTHER:PTN001586581 nucleolus ; GO:0005730 | inferred from direct assay "CG6241, TAF1B" "IPR021752:Transcription initiation factor Rrn7, Zinc-finger, IPR033599:RNA polymerase I transcription initiation factor TAF1B/Rrn7" CG6241 11-Aug-17 DroID_v2017_08 Drer\taf1b Scer\RRN7 - Xtro\taf1b Mmus\Taf1b Hsap\TAF1B FBgn0060493 l(3)S108408c lethal (3) S108408c http://flybase.org/reports/FBgn0060493 gene - - - "1084/08, l(3)S108408c" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033292 Cyp4ad1 Cyp4ad1 http://flybase.org/reports/FBgn0033292 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4ad1, BEST:LD02646, CG2110, Cyp4ad1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG2110 11-Aug-17 DroID_v2017_08 "Drer\cyp20a1, Drer\cyp46a1.4, Drer\cyp4t8, Drer\cyp4v8, Drer\cyp26b1, Drer\cyp3a65, Drer\cyp19a1a, Drer\cyp3c2, Drer\cyp46a1.3, Drer\cyp46a1.1, Drer\cyp46a1.2, Drer\cyp3c4, Drer\cyp26c1, Drer\cyp4f3, Drer\cyp3c3, Drer\cyp4v7, Drer\cyp3c1, Drer\cyp19a1b, Drer\cyp26a1, Drer\LOC100329425" "Scer\DIT2, Scer\ERG5" "Cele\cyp-13A11, Cele\cyp-25A2, Cele\cyp-32A1, Cele\cyp-29A4, Cele\cyp-32B1, Cele\cyp-31A5, Cele\cyp-42A1, Cele\cyp-37B1, Cele\cyp-13A7, Cele\cyp-25A3, Cele\cyp-13A1, Cele\cyp-25A1, Cele\cyp-13A8, Cele\cyp-13A5, Cele\cyp-31A2, Cele\cyp-13A10, Cele\cyp-13A3, Cele\cyp-31A3, Cele\cyp-13A4, Cele\cyp-25A4, Cele\cyp-29A3, Cele\cyp-29A2, Cele\cyp-13A12" "Xtro\cyp19a1, Xtro\cyp20a1, Xtro\cyp26c1, Xtro\cyp4v2, Xtro\cyp4b1.2, Xtro\LOC100487918, Xtro\cyp26a1, Xtro\cyp26b1, Xtro\cyp4b1, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\cyp4f2, Xtro\mgc108213" "Mmus\Cyp4f39, Mmus\Cyp3a41b, Mmus\Cyp4a31, Mmus\Cyp4f16, Mmus\Cyp4x1, Mmus\Cyp4f18, Mmus\Cyp3a11, Mmus\Cyp26b1, Mmus\Cyp3a25, Mmus\Cyp3a44, Mmus\Cyp20a1, Mmus\Cyp4a14, Mmus\Cyp4a32, Mmus\Cyp4f40, Mmus\Cyp4a12b, Mmus\Cyp4f37, Mmus\Cyp4f14, Mmus\Cyp4f17, Mmus\Cyp3a57, Mmus\Cyp26c1, Mmus\Cyp4f13, Mmus\Cyp3a59, Mmus\Cyp46a1, Mmus\Cyp4a12a, Mmus\Cyp4v3, Mmus\Cyp3a41a, Mmus\Cyp4b1, Mmus\Cyp19a1, Mmus\Cyp4a10, Mmus\Cyp3a13, Mmus\Cyp3a16, Mmus\Cyp26a1, Mmus\Cyp4f15" "Hsap\CYP26B1, Hsap\CYP3A7, Hsap\CYP4X1, Hsap\CYP4A22, Hsap\CYP4F12, Hsap\CYP4F8, Hsap\CYP4B1, Hsap\CYP3A5, Hsap\CYP4Z1, Hsap\CYP4F11, Hsap\CYP4A11, Hsap\CYP20A1, Hsap\CYP3A4, Hsap\CYP4V2, Hsap\CYP3A43, Hsap\CYP4F2, Hsap\CYP26A1, Hsap\CYP4F3, Hsap\CYP46A1, Hsap\CYP26C1, Hsap\CYP19A1, Hsap\CYP4F22" FBgn0267468 CR45818 - http://flybase.org/reports/FBgn0267468 non_protein_coding_gene - - - CR45818 - CR45818 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085282 CG34253 - http://flybase.org/reports/FBgn0085282 protein_coding_gene - - - "CG34253, CG32194" - CG34253 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265656 CR44463 - http://flybase.org/reports/FBgn0265656 non_protein_coding_gene - - - "lincRNA.315, CR44463" - CR44463 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000375 crooked-setae crooked setae http://flybase.org/reports/FBgn0000375 - gene - - - "crooked-setae, crk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile" "macrochaeta,acrostichal bristle,tergite,scutellar bristle,microchaeta & adult thorax,microchaeta & adult abdomen | female,female" FBgn0265585 CR44412 - http://flybase.org/reports/FBgn0265585 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR44412 - CR44412 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060675 l(3)S077513b lethal (3) S077513b http://flybase.org/reports/FBgn0060675 gene - - - "0775/13, l(3)S077513b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0000655 fi frail http://flybase.org/reports/FBgn0000655 - gene - - - fi - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,reduced" "wing,macrochaeta" FBgn0013320 Pcp56 Pupal-cuticle-protein-56kD http://flybase.org/reports/FBgn0013320 - gene - - - Pcp56 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036422 CG3868 - http://flybase.org/reports/FBgn0036422 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model CG3868 - CG3868 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0003526 sth small thin http://flybase.org/reports/FBgn0003526 - gene - - - sth - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male fertile,viable,visible" "macrochaeta,adult abdomen,eye,wing" FBgn0005698 l(1)TK101 lethal (1) TK101 http://flybase.org/reports/FBgn0005698 - gene - - - "l101, l(1)TK101" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye FBgn0028494 CG6424 - http://flybase.org/reports/FBgn0028494 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "GH05095, BcDNA:GH05095, anon-WO0153538.34, anon-WO0153538.33, anon-WO0153538.32, anon-WO0118547.96, CG6424" - CG6424 11-Aug-17 DroID_v2017_08 "Drer\fam13b, Drer\si:dkey-11e23.9, Drer\fam13a, Drer\si:ch73-51i5.2" - - "Xtro\fam13b, Xtro\fam13a" "Mmus\Fam13a, Mmus\Fam13b, Mmus\Fam13c" "Hsap\FAM13B, Hsap\FAM13A, Hsap\FAM13C" viable FBgn0265629 CG44437 - http://flybase.org/reports/FBgn0265629 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44437, CG1903" - CG44437 11-Aug-17 DroID_v2017_08 - - Cele\Y32B12B.4 - Mmus\AI481877 - FBgn0039771 Osi23 Osiris 23 http://flybase.org/reports/FBgn0039771 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG15538, Osi23" IPR012464:Protein of unknown function DUF1676 CG15538 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060447 l(3)S122211 lethal (3) S122211 http://flybase.org/reports/FBgn0060447 gene - - - "1222/11, l(3)S122211" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0043847 412\ORF3 412 element ORF3 http://flybase.org/reports/FBgn0043847 transposable_element_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001969, InterPro:IPR001995" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001969, InterPro:IPR001995 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584" - "412\ORF3, ORF3" "IPR034145:RTVL-H retropepsin domain, IPR026523:Paraneoplastic antigen Ma, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain, IPR021109:Aspartic peptidase domain, IPR001969:Aspartic peptidase, active site, IPR001995:Peptidase A2A, retrovirus, catalytic, IPR018061:Retropepsins, IPR015416:Zinc finger, H2C2-type, histone UAS binding" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083030 snoRNA:Psi18S-525i snoRNA:Psi18S-525i http://flybase.org/reports/FBgn0083030 snoRNA_gene - - - "snoRNA:Psi18S-525i, psi18S-525i, CR34584" - CR34584 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005452 l(1)v252 lethal (1) v252 http://flybase.org/reports/FBgn0005452 - gene - - - "l(1)252, l(1)v252" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039349 Ssadh Succinic semialdehyde dehydrogenase http://flybase.org/reports/FBgn0039349 protein_coding_gene succinate-semialdehyde dehydrogenase [NAD(P)+] activity ; GO:0009013 | inferred from electronic annotation with InterPro:IPR010102 succinate-semialdehyde dehydrogenase (NAD+) activity ; GO:0004777 | inferred from sequence or structural similarity with UniProtKB:P51649 succinate-semialdehyde dehydrogenase (NAD+) activity ; GO:0004777 | inferred from direct assay "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010102, InterPro:IPR015590, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163, InterPro:IPR029510 gamma-aminobutyric acid catabolic process ; GO:0009450 | inferred from sequence or structural similarity with UniProtKB:P51649" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:2441982 "anon-WO0118547.428, SSADH, DmSSADH, Ssadh, CG4685, ssadh" "IPR015590:Aldehyde dehydrogenase domain, IPR010102:Succinate semialdehyde dehydrogenase, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR029510:Aldehyde dehydrogenase, glutamic acid active site" CG4685 11-Aug-17 DroID_v2017_08 Drer\aldh5a1 Scer\UGA2 Cele\alh-7 Xtro\aldh5a1 Mmus\Aldh5a1 Hsap\ALDH5A1 "viable,visible" "chaeta,supernumerary" DRSC15621 K 0.063487575 0.113194854 0.067524299 0.612225239 0.02546745 2.944768066 FBgn0017544 SAR Scaffold Attachment Region http://flybase.org/reports/FBgn0017544 - region - - - "MAR, MAR/SAR, dSAR, SAR" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036505 CG7945 - http://flybase.org/reports/FBgn0036505 protein_coding_gene - protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000269264 - "CG17014, CG7945" - CG7945 11-Aug-17 DroID_v2017_08 Drer\bag2 - Cele\unc-23 Xtro\bag2 Mmus\Bag2 Hsap\BAG2 viable FBgn0000902 fs(1)M111 female sterile (1) M111 http://flybase.org/reports/FBgn0000902 - gene - - - fs(1)M111 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0044339 17.6\gag 17.6 element gag http://flybase.org/reports/FBgn0044339 transposable_element_gene - - - "17.6\gag, gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027518 Wdr24 WD repeat domain 24 http://flybase.org/reports/FBgn0027518 - protein_coding_gene - positive regulation of macroautophagy ; GO:0016239 | inferred from mutant phenotype inferred from genetic interaction with Nprl3 positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype positive regulation of TORC1 signaling ; GO:1904263 | inferred from mutant phenotype positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype lysosomal lumen acidification ; GO:0007042 | inferred from mutant phenotype lysosome ; GO:0005764 | inferred from direct assay autolysosome ; GO:0044754 | inferred from direct assay Seh1-associated complex ; GO:0035859 | inferred from direct assay GATOR2 complex ; GO:0061700 | traceable author statement Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000005498 "BcDNA:LD21720, CG7609, SEA2, FBtr0085543, Wdr24, Sea2" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like" CG7609 11-Aug-17 DroID_v2017_08 Drer\wdr24 "Scer\MSI1, Scer\RTC1" Cele\Y32H12A.8 Xtro\wdr24 Mmus\Wdr24 Hsap\WDR24 "viable,male fertile,female fertile,fertile" FBgn0038485 CG5255 - http://flybase.org/reports/FBgn0038485 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP141, CG5255" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG5255 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001088, Drer\LOC103908930" - Cele\svh-1 - "Mmus\Try5, Mmus\Egfbp2, Mmus\Prss55" "Hsap\PRSS57, Hsap\KLK14, Hsap\KLK3" viable FBgn0082941 snoRNA:Me28S-A992 snoRNA:Me28S-A992 http://flybase.org/reports/FBgn0082941 snoRNA_gene - - - "snoRNA:Me28S-A992, Me28S-Am992, Me28S-A992, CR34538" - CR34538 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259576 B0617 - http://flybase.org/reports/FBgn0259576 gene - - - B0617 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,tarsal segment,unguis,arista" FBgn0046876 Obp83ef Odorant-binding protein 83ef http://flybase.org/reports/FBgn0046876 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "CG31557, Obp83e, 83f-2, 83f-1, Obp83f, CG15583, 83f, OBP83e, Obp83ef, DmelObp83ef" IPR006170:Pheromone/general odorant binding protein CG31557 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0052357 tRNA:Met-CAT-1-4 transfer RNA:Methionine-CAT 1-4 http://flybase.org/reports/FBgn0052357 tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "AE002602.trna25-MetCAT, tRNA:M:CAT:AE002602-d, CR32357, tRNA:M2:72Fa, tRNA:met2:72Fa, tRNA:M2:72Fb, tRNA:met2:72Fb, tRNA[[2]][Met], chr3L.trna30-MetCAT, tRNA-Met[CAU], tRNA-Met-CAT-1-4, tRNA:Met-CAT-1-4, tRNA:CR32357" - CR32357 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022336 dc dosach http://flybase.org/reports/FBgn0022336 - gene - - - "dos, dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" spindle | maternal effect FBgn0259625 B0211 - http://flybase.org/reports/FBgn0259625 gene - - - B0211 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0030707 CG8916 - http://flybase.org/reports/FBgn0030707 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 GABA-A receptor activity ; GO:0004890 | inferred from electronic annotation with InterPro:IPR001390 "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001390, InterPro:IPR006028, InterPro:IPR006029, InterPro:IPR006201" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201" "CG8916, Lcch-14A" "IPR001390:Gamma-aminobutyric-acid A receptor, alpha subunit, IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000:Neurotransmitter-gated ion-channel, conserved site" CG8916 11-Aug-17 DroID_v2017_08 "Drer\gabrd, Drer\glra3, Drer\gabrg2, Drer\glra4b, Drer\glrba, Drer\gabrz, Drer\glra4a, Drer\si:dkey-52k1.6, Drer\gabrb1, Drer\gabrr2b, Drer\gabrr1, Drer\gabrb3, Drer\gabrb4, Drer\zgc:110204, Drer\LOC100001259, Drer\gabrp, Drer\LOC100330554, Drer\LOC562831, Drer\glrbb, Drer\gabrr2a, Drer\gabrb2, Drer\gabra5, Drer\gabrr3a, Drer\gabra6b, Drer\gabra6a, Drer\glra2, Drer\gabrg3, Drer\gabra1, Drer\gabra3, Drer\si:dkey-155h10.3" - "Cele\lgc-38, Cele\lgc-41, Cele\lgc-40, Cele\lgc-42, Cele\lgc-37, Cele\unc-49, Cele\glc-3, Cele\avr-15, Cele\ggr-1, Cele\lgc-39, Cele\gab-1, Cele\glc-2, Cele\lgc-36, Cele\lgc-44, Cele\glc-4, Cele\avr-14" "Xtro\LOC100490720, Xtro\glra2, Xtro\gabrb3, Xtro\gabra2, Xtro\glrb, Xtro\glra1, Xtro\gabra5, Xtro\glra3, Xtro\gabrd, Xtro\gabrg2, Xtro\gabra6, Xtro\gabrr3, Xtro\gabrp" "Mmus\Gabrb2, Mmus\Gabra1, Mmus\Gabra2, Mmus\Gabrq, Mmus\Gabrg2, Mmus\Gabrd, Mmus\Gabrr3, Mmus\Gabra5, Mmus\Gabra6, Mmus\Glra2, Mmus\Gabre, Mmus\Glra4, Mmus\Glra3, Mmus\Gabrr1, Mmus\Glrb, Mmus\Gabrp, Mmus\Gabrb1, Mmus\Gabrg1, Mmus\Gabrb3, Mmus\Glra1, Mmus\Gabrr2, Mmus\Gabra3, Mmus\Gabrg3, Mmus\Gabra4" "Hsap\GABRD, Hsap\GABRA6, Hsap\GABRB2, Hsap\GLRB, Hsap\GABRA1, Hsap\GABRA5, Hsap\GABRG1, Hsap\GABRB1, Hsap\GABRR3, Hsap\GABRR1, Hsap\GLRA2, Hsap\GABRP, Hsap\GLRA1, Hsap\GLRA3, Hsap\GABRE, Hsap\GABRB3, Hsap\GABRA2, Hsap\GABRR2, Hsap\GABRA3, Hsap\GABRG3, Hsap\GABRA4, Hsap\GABRG2, Hsap\GLRA4, Hsap\GABRQ" viable FBgn0259408 C272 - http://flybase.org/reports/FBgn0259408 gene - - - C272 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,chaeta,ectopic" FBgn0260762 CG42560 - http://flybase.org/reports/FBgn0260762 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG30182, CG42560" - CG42560 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052061 CG32061 - http://flybase.org/reports/FBgn0052061 protein_coding_gene - - - "CG8040, CG32061" - CG32061 11-Aug-17 DroID_v2017_08 "Drer\npepl1, Drer\lap3, Drer\zgc:152830" - - Xtro\lap3 "Mmus\Lap3, Mmus\Npepl1" "Hsap\LAP3, Hsap\NPEPL1" FBgn0022148 l(2)k06006 lethal (2) k06006 http://flybase.org/reports/FBgn0022148 - gene - - - l(2)k06006 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085590 CG41272 - http://flybase.org/reports/FBgn0085590 protein_coding_gene - - - CG41272 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005759 l(1)TK403 lethal (1) TK403 http://flybase.org/reports/FBgn0005759 - gene - - - "l403, l(1)TK403" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0026324 Taf10b TBP-associated factor 10b http://flybase.org/reports/FBgn0026324 - protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VWY6 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay" histone H3 acetylation ; GO:0043966 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11543 inferred from sequence or structural similarity with SGD:S000002574 SAGA complex ; GO:0000124 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11543 inferred from sequence or structural similarity with SGD:S000002574 transcription factor TFIID complex ; GO:0005669 | inferred from direct assay "dTAF[[II]]16, dmTAF10b, TAF, TFIID, TAF[[II]], TAF[[II]]16, TAF10b, CG3069, dtafII16, TAFII16, TafII16, Taf16, Taf10b, Taf10, dTAF10b" "IPR003923:Transcription initiation factor TFIID, 23-30kDa subunit" CG3069 11-Aug-17 DroID_v2017_08 Drer\taf10 Scer\TAF10 Cele\taf-10 Xtro\taf10 Mmus\Taf10 Hsap\TAF10 "viable,visible" trichogen cell DRSC26605 EK -0.871836093 1.259682869 -2.992211385 0.647254997 0.832574505 1.76930272 FBgn0011122 l(1)Q83 lethal (1) Q83 http://flybase.org/reports/FBgn0011122 FBgn0010210 gene - - - l(1)Q83 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034715 Oatp58Db Organic anion transporting polypeptide 58Db http://flybase.org/reports/FBgn0034715 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from direct assay active transmembrane transporter activity ; GO:0022804 | inferred from mutant phenotype organic substance transport ; GO:0071702 | inferred from direct assay excretion ; GO:0007588 | inferred from mutant phenotype basolateral plasma membrane ; GO:0016323 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay "58Db, oatp 58Db, CG3382, Oatp58Db" "IPR020846:Major facilitator superfamily domain, IPR004156:Organic anion transporter polypeptide OATP" CG3382 11-Aug-17 DroID_v2017_08 "Drer\slco2b1, Drer\LOC100334356, Drer\slco1f2, Drer\slco3a1, Drer\slco1d1, Drer\slco1c1, Drer\LOC101883455, Drer\LOC570448, Drer\slco1f3, Drer\slco5a1, Drer\LOC100536648, Drer\slco2a1, Drer\slco1f1, Drer\slco4a1, Drer\slco1f4" - "Cele\F21G4.1, Cele\Y70G10A.3, Cele\F47E1.2, Cele\K02G10.5, Cele\F53B1.8, Cele\F47E1.4, Cele\Y32F6B.1" "Xtro\slco4a1, Xtro\slco5a1, Xtro\slco3a1, Xtro\slco2a1, Xtro\slco4c1, Xtro\slco1b3" "Mmus\Slco4c1, Mmus\Slco5a1, Mmus\Gm5724, Mmus\Slco1a1, Mmus\Slco6d1, Mmus\Slco1a4, Mmus\Gm6614, Mmus\Slco2a1, Mmus\Slco4a1, Mmus\Slco3a1, Mmus\Slco6c1, Mmus\Slco1c1, Mmus\Slco1b2, Mmus\Slco1a5, Mmus\Slco1a6, Mmus\Slco2b1" "Hsap\SLCO6A1, Hsap\SLCO1B1, Hsap\SLCO5A1, Hsap\SLCO1B3, Hsap\SLCO1C1, Hsap\SLCO4C1, Hsap\SLCO2A1, Hsap\SLCO4A1, Hsap\SLCO1B7, Hsap\SLCO2B1, Hsap\SLCO1A2, Hsap\SLCO3A1" Malpighian tubule FBgn0013478 l(1)1P2 lethal (1) 1P2 http://flybase.org/reports/FBgn0013478 - gene - - - l(1)1P2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,rescuable maternal effect" "segment,germline clone" FBgn0051495 CG31495 - http://flybase.org/reports/FBgn0051495 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 - - "CG9931, CG31495" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003959:ATPase, AAA-type, core" CG31495 11-Aug-17 DroID_v2017_08 "Drer\nsfb, Drer\nsfa" Scer\SEC18 Cele\nsf-1 - Mmus\Nsf Hsap\NSF DRSC16762 K 0.327626616 0.509443831 -0.480955318 0.197594255 -0.729128987 1.518086278 FBgn0069938 CG41106 - http://flybase.org/reports/FBgn0069938 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of protein dephosphorylation ; GO:0035307 | inferred from electronic annotation with InterPro:IPR019168 biological_process ; GO:0008150 | no biological data available Nem1-Spo7 phosphatase complex ; GO:0071595 | inferred from electronic annotation with InterPro:IPR019168 cellular_component ; GO:0005575 | no biological data available CG41106 IPR019168:Nuclear envelope phosphatase-regulatory subunit 1 CG41106 11-Aug-17 DroID_v2017_08 Drer\cnep1r1 - Cele\nepr-1 Xtro\cnep1r1 Mmus\Cnep1r1 Hsap\CNEP1R1 FBgn0050286 CG30286 - http://flybase.org/reports/FBgn0050286 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP37, SPH37, CG10450, CG30286" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site" CG30286 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.15, Drer\si:dkey-21e2.7, Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.9, Drer\gzm3, Drer\si:dkey-21e2.12" - "Cele\try-1, Cele\try-3" - "Mmus\Ctsg, Mmus\Gzmb, Mmus\Mcpt9, Mmus\Mcpt4, Mmus\Cma2, Mmus\Mcpt8, Mmus\Gzmc, Mmus\Cma1, Mmus\Gzmd, Mmus\Klk1b9, Mmus\Mcpt1, Mmus\Gzme, Mmus\Gzmg, Mmus\Gzmf, Mmus\Klk1b5, Mmus\Klk6" "Hsap\CTSG, Hsap\GZMH, Hsap\CMA1, Hsap\GZMB" viable FBgn0052511 CR32511 - http://flybase.org/reports/FBgn0052511 pseudogene_attribute - - - "CG32511, CR32511" - CR32511 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0053690 CG33690 - http://flybase.org/reports/FBgn0053690 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33690 IPR010512:Protein of unknown function DUF1091 CG33690 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027626 ss(2)28Aa ss(2)28Aa http://flybase.org/reports/FBgn0027626 FBgn0027638 gene - - - "mfs(2)28Aa, ss(2)28Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "semi-sterile,recessive" FBgn0060531 l(3)S101206a lethal (3) S101206a http://flybase.org/reports/FBgn0060531 gene - - - "1012/06, l(3)S101206a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0034488 CG11208 - http://flybase.org/reports/FBgn0034488 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011766 thiamine pyrophosphate binding ; GO:0030976 | inferred from electronic annotation with InterPro:IPR011766, InterPro:IPR012000, InterPro:IPR012001 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR012000" fatty acid alpha-oxidation ; GO:0001561 | inferred from sequence or structural similarity with HGNC:17856 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:17856 inferred from sequence model "anon-WO0118547.196, CG11208" "IPR011766:Thiamine pyrophosphate enzyme, C-terminal TPP-binding, IPR012000:Thiamine pyrophosphate enzyme, central domain, IPR012001:Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain, IPR029061:Thiamin diphosphate-binding fold, IPR029035:DHS-like NAD/FAD-binding domain" CG11208 11-Aug-17 DroID_v2017_08 "Drer\ilvbl, Drer\hacl1" "Scer\THI3, Scer\ARO10, Scer\ILV2, Scer\PDC6, Scer\PDC1, Scer\PDC5, Scer\YEL020C" "Cele\T26C12.1, Cele\B0334.3" "Xtro\hacl1, Xtro\ilvbl" "Mmus\Ilvbl, Mmus\Hacl1" "Hsap\HACL1, Hsap\ILVBL" "partially lethal - majority die,some die during pupal stage" FBgn0067670 ovo::Bole\ovo ovo::Bole\ovo http://flybase.org/reports/FBgn0067670 engineered_fusion_gene - - - ovo::Bole\ovo - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262975 cnc cap-n-collar http://flybase.org/reports/FBgn0262975 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from direct assay transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from biological aspect of ancestor with PANTHER:PTN000696756 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with maf-S protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" head development ; GO:0060322 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype pharynx development ; GO:0060465 | inferred from mutant phenotype maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification ; GO:0042070 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype regulation of bicoid mRNA localization ; GO:0008359 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000696756 "CnC, cnc, Cnc, Nrf2, CG43286, CG4578, CNC, l(3)j5E7, CNC_DROME, 5134, l(3)03921, CG4566, CG17894, anon-WO0153538.7, anon-WO0153538.6, BcDNA:RE05559, CG13826, cnc-C, DM12, CncC, dNrf2" "IPR004826:Basic leucine zipper domain, Maf-type, IPR004827:Basic-leucine zipper domain, IPR008917:Transcription factor, Skn-1-like, DNA-binding domain" CG43286 11-Aug-17 DroID_v2017_08 "Drer\nfe2l2b, Drer\nfe2l2a, Drer\bach1a, Drer\nfe2l1a, Drer\nfe2l3, Drer\klhl6, Drer\bach1b, Drer\nfe2l1b, Drer\nfe2, Drer\bach2a, Drer\bach2b" - "Cele\skn-1, Cele\sknr-1" "Xtro\nfe2, Xtro\bach1, Xtro\bach2, Xtro\nfe2l3, Xtro\nfe2l2, Xtro\nfe2l1" "Mmus\Nfe2, Mmus\Nfe2l3, Mmus\Nfe2l1, Mmus\Nfe2l2, Mmus\Klhl6, Mmus\Bach1, Mmus\Bach2" "Hsap\BACH1, Hsap\NFE2L1, Hsap\KLHL6, Hsap\NFE2, Hsap\NFE2L2, Hsap\NFE2L3, Hsap\BACH2" " embryonic stage | stage >14 , embryonic stage | stage >=6 , embryonic stage | early " "

ubiquitous , embryonic labral segment

, embryonic mandibular segment

" FBgn0014349 ms(2)HB194 ms(2)HB194 http://flybase.org/reports/FBgn0014349 - gene - - - ms(2)HB194 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060330 l(3)S146006b lethal (3) S146006b http://flybase.org/reports/FBgn0060330 gene - - - "l(3)S146006, 1460/06, l(3)S146006b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0017580 M(1)14E M(1)14E http://flybase.org/reports/FBgn0017580 - gene - - - M(1)14E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013571 l(3)ry82 lethal (3) ry82 http://flybase.org/reports/FBgn0013571 - gene - - - "l(3)82, l(3)ry82" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039774 CDase Ceramidase http://flybase.org/reports/FBgn0039774 protein_coding_gene ceramidase activity ; GO:0017040 | inferred from direct assay ceramidase activity ; GO:0017040 | inferred from mutant phenotype sphingolipid metabolic process ; GO:0006665 | inferred from direct assay hatching behavior ; GO:0035187 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype ceramide catabolic process ; GO:0046514 | inferred from direct assay synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype synaptic vesicle fusion to presynaptic active zone membrane ; GO:0031629 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG1471, fcd, anon-WO0118547.407, CDase, cdase, slab, Cdase" "IPR006823:Neutral/alkaline nonlysosomal ceramidase, IPR031331:Neutral/alkaline non-lysosomal ceramidase, C-terminal, IPR031329:Neutral/alkaline non-lysosomal ceramidase, N-terminal" CG1471 11-Aug-17 DroID_v2017_08 Drer\asah2 - - "Xtro\LOC100494440, Xtro\asah2" Mmus\Asah2 "Hsap\ASAH2, Hsap\ASAH2B" "locomotor behavior defective,recessive,neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,increased cell death,lethal" "synaptic vesicle,synaptic vesicleslab-3),eye photoreceptor cell,rhabdomere,eye disc" FBgn0033403 CG13739 - http://flybase.org/reports/FBgn0033403 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 - - "BcDNA:GH21254, CG13739" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG13739 11-Aug-17 DroID_v2017_08 - - - - - - lethal heart primordium FBgn0065381 l(2)SH1666 lethal (2) SH1666 http://flybase.org/reports/FBgn0065381 gene - - - "l(2)SH1666, l(2)SH2 1666" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065901 l(2)SH0200 lethal (2) SH0200 http://flybase.org/reports/FBgn0065901 gene - - - "l(2)SH0200, l(2)SH2 0200" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022203 l(2)k04512 lethal (2) k04512 http://flybase.org/reports/FBgn0022203 - gene - - - l(2)k04512 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043845 Ama::Nrg Ama::Nrg http://flybase.org/reports/FBgn0043845 engineered_fusion_gene - - - Ama::Nrg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038771 CG4390 - http://flybase.org/reports/FBgn0038771 protein_coding_gene S-formylglutathione hydrolase activity ; GO:0018738 | inferred from electronic annotation with InterPro:IPR014186 formaldehyde catabolic process ; GO:0046294 | inferred from electronic annotation with InterPro:IPR014186 - CG4390 "IPR000801:Putative esterase, IPR014186:S-formylglutathione hydrolase, IPR029058:Alpha/Beta hydrolase fold" CG4390 11-Aug-17 DroID_v2017_08 "Drer\esd, Drer\ccdc39" Scer\YJL068C Cele\Y48G10A.1 "Xtro\ccdc39, Xtro\esd" "Mmus\Esd, Mmus\Ccdc39" "Hsap\CCDC39, Hsap\ESD" FBgn0053239 Ste:CG33239 Ste:CG33239 http://flybase.org/reports/FBgn0053239 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG32605, CG33239, Ste:CG33239" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33239 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0038146 CG9799 - http://flybase.org/reports/FBgn0038146 protein_coding_gene - cellular response to starvation ; GO:0009267 | inferred from expression pattern rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000356653 Pwp2p-containing subcomplex of 90S preribosome ; GO:0034388 | inferred from biological aspect of ancestor with PANTHER:PTN000356653 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000356653 CG9799 "IPR001680:WD40 repeat, IPR007319:Small-subunit processome, Utp21, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG9799 11-Aug-17 DroID_v2017_08 Drer\wdr36 Scer\UTP21 Cele\Y45F10D.7 Xtro\wdr36 Mmus\Wdr36 Hsap\WDR36 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC16567 E 1.477590584 0.453170864 1.884111752 0.185797449 0.800098502 0.442015867 FBgn0005211 l(3)hd lethal (3) head defect http://flybase.org/reports/FBgn0005211 - gene - - - l(3)hd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" head FBgn0024588 l(2)k02615 lethal (2) k02615 http://flybase.org/reports/FBgn0024588 - gene - - - "26/15, l(2)k02615" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037659 Kdm2 Lysine (K)-specific demethylase 2 http://flybase.org/reports/FBgn0037659 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002857 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002857 histone demethylase activity (H3-trimethyl-K4 specific) ; GO:0034647 | inferred from mutant phenotype ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model "segment specification ; GO:0007379 | inferred from genetic interaction with Pc inferred from genetic interaction with trx inferred from genetic interaction with ash1 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model histone H3-K4 demethylation, trimethyl-H3-K4-specific ; GO:0034721 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype histone H2A ubiquitination ; GO:0033522 | inferred from direct assay inferred from mutant phenotype histone H3-K36 demethylation ; GO:0070544 | inferred from direct assay inferred from mutant phenotype" "SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model PcG protein complex ; GO:0031519 | inferred from physical interaction with Sce, Psc nucleus ; GO:0005634 | inferred from direct assay" "Kdm2, dKDM2, CG11033, dkdm2, dRAF1, FBXL19, JHDM1, dKdm2, KDM2" "IPR001810:F-box domain, IPR002857:Zinc finger, CXXC-type, IPR003347:JmjC domain, IPR006553:Leucine-rich repeat, cysteine-containing subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR019787:Zinc finger, PHD-finger, IPR001611:Leucine-rich repeat" CG11033 11-Aug-17 DroID_v2017_08 "Drer\kdm2bb, Drer\phf2, Drer\fbxl6, Drer\kdm2ba, Drer\kdm2aa, Drer\kdm7aa, Drer\fbxl17, Drer\si:dkey-192l18.9, Drer\zgc:158376, Drer\LOC100536129, Drer\fbxl15, Drer\kdm7ab, Drer\fbxl4, Drer\kdm2ab, Drer\phf8" "Scer\GRR1, Scer\JHD1" "Cele\jmjd-1.1, Cele\jhdm-1, Cele\jmjd-1.2" "Xtro\kdm7a, Xtro\phf8, Xtro\fbxl4, Xtro\kdm2b, Xtro\fbxl19, Xtro\fbxl12, Xtro\kdm2a, Xtro\phf2" "Mmus\Fbxl6, Mmus\Lrrc29, Mmus\Phf8, Mmus\Phf2, Mmus\Fbxl19, Mmus\4921501E09Rik, Mmus\Fbxl21, Mmus\Kdm2b, Mmus\Fbxl17, Mmus\Kdm7a, Mmus\Fbxl4, Mmus\Kdm2a" "Hsap\FBXL17, Hsap\FBXL6, Hsap\PHF2, Hsap\LRRC29, Hsap\FBXL19, Hsap\PHF8, Hsap\FBXL4, Hsap\KDM2B, Hsap\KDM7A, Hsap\KDM2A" "lethal,viable,partially lethal - majority die,recessive" nucleolus FBgn0028963 Or49b Odorant receptor 49b http://flybase.org/reports/FBgn0028963 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from direct assay olfactory receptor activity ; GO:0004984 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b sensory perception of smell ; GO:0007608 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "49b, DOR105, CG17584, AN13, 49D.1, Or49b" "IPR004117:Olfactory receptor, insect" CG17584 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0262335 mir-2492 mir-2492 stem loop http://flybase.org/reports/FBgn0262335 miRNA_gene - - - "mir-2492, CR43042, dme-mir-2492, miR-2492" - CR43042 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0085474 CG34445 - http://flybase.org/reports/FBgn0085474 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34445, CG13513, CG30219" IPR006629:LPS-induced tumour necrosis factor alpha factor CG34445 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0039664 CG2006 - http://flybase.org/reports/FBgn0039664 protein_coding_gene - - - CG2006 IPR005636:DTW CG2006 11-Aug-17 DroID_v2017_08 Drer\dtwd1 - Cele\Y53C12A.10 Xtro\dtwd1 Mmus\Dtwd1 Hsap\DTWD1 FBgn0027971 l(3)S142909 lethal (3) S142909 http://flybase.org/reports/FBgn0027971 gene - - - "1429/09, l(3)S142909" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0035377 CG14952 - http://flybase.org/reports/FBgn0035377 protein_coding_gene - - - CG14952 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" DRSC08412 IEK -1.85987366 -3.989084073 -3.913683202 -5.010327823 1.619893523 3.329087426 FBgn0014380 RhoL Rho-like http://flybase.org/reports/FBgn0014380 "FBgn0019864, FBgn0020619" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225 GTPase activity ; GO:0003924 | traceable author statement GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with HGNC:9801 calcium ion binding ; GO:0005509 | non-traceable author statement" "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578 melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype hemocyte development ; GO:0007516 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement cell adhesion ; GO:0007155 | inferred from mutant phenotype" intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003578 cellular_component ; GO:0005575 | no biological data available "rhol, DmRHO-L, CG9366, Mes1, DRhoL, RhoL/Rac3, Drac3, G, rol, rhoL, anon-EST:CL1c2, Rhol, Rac3, RhoL, Rho-like, D-RhoL, 9366, RhoG" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR003578:Small GTPase superfamily, Rho type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9366 11-Aug-17 DroID_v2017_08 "Drer\rnd3b, Drer\rhoab, Drer\cdc42l2, Drer\LOC100331257, Drer\rac3a, Drer\rhocb, Drer\cdc42l, Drer\rac3b, Drer\rhoj, Drer\rhov, Drer\rhobtb2a, Drer\rac1b, Drer\rhof, Drer\rac1a, Drer\rhogc, Drer\rhoac, Drer\rhoga, Drer\rhoca, Drer\rhobtb1, Drer\rnd1a, Drer\rnd1b, Drer\si:dkey-263f15.2, Drer\rhoh, Drer\cdc42, Drer\rhogb, Drer\rnd3a, Drer\rnd2, Drer\rhoub, Drer\rhoua, Drer\rac1l, Drer\rhoaa, Drer\si:ch211-133l11.10, Drer\si:dkey-6b12.5, Drer\rhobtb2b, Drer\rhoq" "Scer\RHO4, Scer\RHO2, Scer\RHO3, Scer\CDC42, Scer\RHO1, Scer\GEM1, Scer\RHO5" "Cele\miro-1, Cele\mig-2, Cele\crp-1" "Xtro\rnd3, Xtro\rhov, Xtro\rhoa.2, Xtro\rhof, Xtro\rac1, Xtro\rhoa, Xtro\rhob, Xtro\rac2, Xtro\rhoj, Xtro\rhobtb1, Xtro\rhobtb3, Xtro\cdc42, Xtro\rnd1, Xtro\rhoc, Xtro\rhou, Xtro\rhobtb2" "Mmus\Rhobtb1, Mmus\Rhou, Mmus\Rhof, Mmus\Cdc42, Mmus\Rhoc, Mmus\Rhoa, Mmus\Rhoh, Mmus\Rnd1, Mmus\Rhobtb2, Mmus\Rhob, Mmus\Rnd3, Mmus\Rac1, Mmus\Rac3, Mmus\Rhod, Mmus\Rhog, Mmus\Rnd2, Mmus\Rhov, Mmus\Rac2, Mmus\Rhoj, Mmus\4930544G11Rik, Mmus\Rhobtb3, Mmus\Rhoq, Mmus\Rhot1" "Hsap\RHOA, Hsap\RND3, Hsap\RHOG, Hsap\RHOQ, Hsap\RND1, Hsap\RHOU, Hsap\RHOF, Hsap\RHOBTB3, Hsap\RHOT2, Hsap\RHOJ, Hsap\RAC1, Hsap\RND2, Hsap\RHOT1, Hsap\RHOBTB1, Hsap\RHOC, Hsap\CDC42, Hsap\RAC3, Hsap\RHOH, Hsap\RHOB, Hsap\RHOBTB2, Hsap\RAC2, Hsap\RHOV, Hsap\RHOD" " embryonic stage | stage >5 , embryonic stage | stage 11 , embryonic stage -- adult stage , embryonic stage | late , embryonic stage | stage 5 , embryonic stage | stage >11 , embryonic stage , embryonic stage | stage 6-10 , embryonic stage | cellular blastoderm " " mesoderm

, head mesoderm

, hemocyte

, mesoderm anlage

,

ubiquitous , ventral furrow

, ventral furrow | anterior

" "immune response defective,neuroanatomy defective,viable,lethal" "intersegmental nerve,anterior fascicle & synapse | supernumerary,nurse cell,follicle cell,border follicle cell,polar follicle cell,hemocyte" DRSC16824 IE -0.271317847 -2.091840094 0.509538778 1.628428859 0.146224726 0.784276087 FBgn0034439 CG10062 - http://flybase.org/reports/FBgn0034439 protein_coding_gene - - - "anon-WO0140519.226, CG10062" IPR007484:Peptidase M28 CG10062 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\PFF1, Scer\YDR415C, Scer\VPS70, Scer\APE3" "Cele\C44B7.11, Cele\B0495.7" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 "viable,visible" trichogen cell FBgn0029736 CG4041 - http://flybase.org/reports/FBgn0029736 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 protein kinase activity ; GO:0004672 | NOT inferred from key residues GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 protein phosphorylation ; GO:0006468 | NOT inferred from key residues regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Golgi organization ; GO:0007030 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG4041 "IPR000195:Rab-GTPase-TBC domain, IPR000719:Protein kinase domain, IPR001763:Rhodanese-like domain, IPR011009:Protein kinase-like domain" CG4041 11-Aug-17 DroID_v2017_08 "Drer\tbc1d31, Drer\tbck" "Scer\BUB2, Scer\GYP1" Cele\tbck-1 "Xtro\tbck, Xtro\tbc1d31" "Mmus\Tbc1d31, Mmus\Tbck" "Hsap\TBC1D31, Hsap\TBCK" viable FBgn0038745 CG4538 - http://flybase.org/reports/FBgn0038745 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR004487 unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR004487 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence or structural similarity with UniProtKB:O76031" protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR004487 proteolysis ; GO:0006508 | inferred from sequence or structural similarity with UniProtKB:O76031 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O76031 "CG4538, ClpX" "IPR003593:AAA+ ATPase domain, IPR004487:Clp protease, ATP-binding subunit ClpX, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019489:Clp ATPase, C-terminal, IPR003959:ATPase, AAA-type, core" CG4538 11-Aug-17 DroID_v2017_08 "Drer\clpxb, Drer\LOC108179032, Drer\clpxa" Scer\MCX1 "Cele\D2030.2, Cele\K07A3.3" Xtro\clpx Mmus\Clpx Hsap\CLPX "viable,visible" "trichogen cell,supernumerary" FBgn0033580 CG13231 - http://flybase.org/reports/FBgn0033580 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13231 - CG13231 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC26554 K -0.282507257 0.420596799 0.103653311 -0.233349374 0.779226089 -2.05662281 FBgn0016850 l(1)N31 lethal (1) N31 http://flybase.org/reports/FBgn0016850 - gene - - - "l(1)N31, N31" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038070 CG6753 - http://flybase.org/reports/FBgn0038070 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - CG6753 "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG6753 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH2, Scer\TGL1, Scer\YEH1" "Cele\lipl-5, Cele\lipl-8, Cele\lipl-6, Cele\lipl-7, Cele\lipl-3, Cele\lipl-4, Cele\lipl-2, Cele\lipl-1" Xtro\lipa "Mmus\Lipo3, Mmus\Lipa, Mmus\Lipo4, Mmus\Lipk, Mmus\Lipm, Mmus\Lipo2, Mmus\Lipf, Mmus\Lipo1, Mmus\Lipn" "Hsap\LIPF, Hsap\LIPM, Hsap\LIPA, Hsap\LIPK, Hsap\LIPJ, Hsap\LIPN" viable FBgn0037547 CG7910 - http://flybase.org/reports/FBgn0037547 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay - CG7910 IPR023631:Amidase signature domain CG7910 11-Aug-17 DroID_v2017_08 "Drer\faah, Drer\faah2a, Drer\faah2b" Scer\AMD2 "Cele\Y53F4B.18, Cele\faah-3, Cele\faah-5, Cele\faah-2, Cele\faah-1, Cele\faah-6" "Xtro\faah.3, Xtro\faah2, Xtro\faah.2, Xtro\faah.1" Mmus\Faah "Hsap\FAAH, Hsap\FAAH2" FBgn0067347 l(3)95Ee lethal (3) 95Ee http://flybase.org/reports/FBgn0067347 gene - - - l(3)95Ee - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,somatic clone,wing vein,wing margin,macrochaeta,embryo" FBgn0014085 anon-20ABb anon-20ABb http://flybase.org/reports/FBgn0014085 - gene - - - anon-20ABb - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065269 l(2)SH2060 lethal (2) SH2060 http://flybase.org/reports/FBgn0065269 gene - - - "l(2)SH2060, l(2)SH2 2060" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035311 CR15821 - http://flybase.org/reports/FBgn0035311 pseudogene_attribute - - - "CG15821, CR15821" - CR15821 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061511 fs(2)AL289 fs(2)AL289 http://flybase.org/reports/FBgn0061511 gene - - - "AL289, fs(2)AL289" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,heat sensitive" FBgn0040655 CG15659 - http://flybase.org/reports/FBgn0040655 protein_coding_gene - - - CG15659 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034880 ItgaPS5 Integrin alphaPS5 subunit http://flybase.org/reports/FBgn0034880 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with mys cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity with scb receptor activity ; GO:0004872 | inferred from sequence or structural similarity with scb cell-matrix adhesion ; GO:0007160 | traceable author statement cell adhesion mediated by integrin ; GO:0033627 | inferred from sequence or structural similarity with mys oocyte growth ; GO:0001555 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | traceable author statement integrin complex ; GO:0008305 | inferred from sequence or structural similarity with mys integrin complex ; GO:0008305 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mys integrin complex ; GO:0008305 | inferred from sequence or structural similarity integrin complex ; GO:0008305 | inferred from sequence or structural similarity with scb "CG5372, CT17068, alphaPS5, alpha-PS5, ItgaPS5, ItgalphaPS5" "IPR000413:Integrin alpha chain, IPR013519:Integrin alpha beta-propellor, IPR013649:Integrin alpha-2, IPR032695:Integrin domain" CG5372 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001082, Drer\itga3a, Drer\itga3b, Drer\itga6a, Drer\itga1, Drer\itga10, Drer\itgae.2, Drer\itga11a, Drer\si:dkey-32n7.4, Drer\itgam, Drer\itga2.2, Drer\itga9, Drer\itga4, Drer\itga11b, Drer\itga6l, Drer\itga6b, Drer\itgae.1" - Cele\ina-1 "Xtro\itga4, Xtro\itga9, Xtro\itga2, Xtro\itga1, Xtro\itga11" "Mmus\Itga11, Mmus\Itga10, Mmus\Itga3, Mmus\Itga9, Mmus\Itga4, Mmus\Itga6, Mmus\Itgae, Mmus\Itgax, Mmus\Itgal, Mmus\Itga7, Mmus\Itga1, Mmus\Itga2, Mmus\Itgam, Mmus\Itgad" "Hsap\ITGA9, Hsap\ITGA3, Hsap\ITGAE, Hsap\ITGAM, Hsap\ITGAL, Hsap\ITGA10, Hsap\ITGAX, Hsap\ITGA7, Hsap\ITGAD, Hsap\ITGA4, Hsap\ITGA2, Hsap\ITGA6, Hsap\ITGA1, Hsap\ITGA11" viable DRSC04501 K -0.429958661 -0.457652414 -0.058476411 -0.415311309 3.064318978 1.05594683 FBgn0027656 h::hkb h::hkb http://flybase.org/reports/FBgn0027656 - engineered_fusion_gene - - - h::hkb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female" FBgn0001564 l(1)19Fe lethal (1) 19Fe http://flybase.org/reports/FBgn0001564 - gene - - - "l(1)W-4, w-4, W4, W-4, 16, l(1)19Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033212 LRR Leucine-rich repeat http://flybase.org/reports/FBgn0033212 protein_coding_gene - immune response ; GO:0006955 | inferred from expression pattern negative regulation of NIK/NF-kappaB signaling ; GO:1901223 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from sequence model response to insecticide ; GO:0017085 | inferred from expression pattern negative regulation of immune response ; GO:0050777 | inferred from mutant phenotype muscle tendon junction ; GO:0005927 | inferred from direct assay "CG1576, LRR, CG1399, Dmel\LRR" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR031943:CARMIL, C-terminal domain" CG1399 11-Aug-17 DroID_v2017_08 "Drer\lrrc16b, Drer\cfdp1, Drer\rltpr" - Cele\crml-1 "Xtro\lrrc16b, Xtro\lrrc16a" "Mmus\Carmil2, Mmus\Rnh1, Mmus\Carmil3, Mmus\Carmil1" "Hsap\CARMIL3, Hsap\CARMIL2, Hsap\CARMIL1, Hsap\RNH1" viable FBgn0000644 Fcp3C Follicle cell protein 3C http://flybase.org/reports/FBgn0000644 FBgn0041573 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4015, EG:140G11.2, Ecp3C, VMP3C, Fcp3C" - CG4015 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage | stage S9-11 , adult stage && oogenesis stage " follicle cell

"viable,fertile" FBgn0017556 Prosalpha4T2 "Proteasome alpha4 subunit, Testis-specific 2" http://flybase.org/reports/FBgn0017556 - protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000005398 "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from sequence or structural similarity with SGD:S000005398" "alpha4t2, a4-t2, dalpha7, alpha4t2_dm, CG4569, pros28.1B, Prosalpha4T2, Pros28.1B, alpha4T2" "IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR023332:Proteasome alpha-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG4569 11-Aug-17 DroID_v2017_08 "Drer\psma2, Drer\psma8" Scer\PRE6 Cele\pas-4 "Xtro\psma7, Xtro\psma2, Xtro\psma5" "Mmus\Psma8, Mmus\Psma2, Mmus\Psma7, Mmus\Psma5" "Hsap\PSMA2, Hsap\PSMA8, Hsap\PSMA7, Hsap\PSMA5" "partially lethal - majority die,some die during pupal stage" FBgn0266534 CG45095 - http://flybase.org/reports/FBgn0266534 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45095 - CG45095 11-Aug-17 DroID_v2017_08 - - "Cele\pes-5, Cele\F15D4.5, Cele\T11F9.10, Cele\Y20F4.8, Cele\T26C11.4, Cele\ZC53.2, Cele\T16H12.2, Cele\F40D4.13" - Mmus\Zcchc16 - FBgn0032462 CG16800 - http://flybase.org/reports/FBgn0032462 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG16800 IPR031959:Protein of unknown function DUF4779 CG16800 11-Aug-17 DroID_v2017_08 - - "Cele\C17F3.3, Cele\Y39B6A.1" - - - "partially lethal - majority die,some die during pupal stage" FBgn0266620 CR45127 - http://flybase.org/reports/FBgn0266620 non_protein_coding_gene - - - CR45127 - CR45127 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065166 l(3)SH033 lethal (3) SH033 http://flybase.org/reports/FBgn0065166 gene - - - "l(3)SH033, l(2)SH3 033" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010679 l(2)s1864 lethal (2) s1864 http://flybase.org/reports/FBgn0010679 - gene - - - l(2)s1864 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033363 CG13744 - http://flybase.org/reports/FBgn0033363 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "c-SP67, SP67, CG13744" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG13744 11-Aug-17 DroID_v2017_08 "Drer\zgc:171592, Drer\zgc:154142, Drer\zgc:112285, Drer\si:dkey-57c15.4, Drer\ela3l, Drer\zgc:112302, Drer\ela2l, Drer\ctrb1, Drer\zgc:112160, Drer\zgc:92511, Drer\si:dkey-238d18.3, Drer\zgc:92041, Drer\ela2, Drer\LOC562139, Drer\ctrl, Drer\zgc:112368, Drer\zgc:92745" - Cele\svh-1 "Xtro\LOC100135144, Xtro\cela2a, Xtro\ctrb2, Xtro\ctrb1, Xtro\cela3a" "Mmus\Klk1b27, Mmus\Cela3b, Mmus\Ctrc, Mmus\Klk1b21, Mmus\Klk1b5, Mmus\Klk1b16, Mmus\Klk1b9, Mmus\Klk1b26, Mmus\Klk1b1, Mmus\Klkb1, Mmus\Klk1b24, Mmus\Klk1, Mmus\Egfbp2, Mmus\Klk1b8, Mmus\Ctrl, Mmus\Klk1b3, Mmus\Klk1b11, Mmus\Klk1b22, Mmus\Cela2a, Mmus\Ctrb1, Mmus\Klk1b4, Mmus\F11, Mmus\Cela3a, Mmus\Klk11, Mmus\Cela1" "Hsap\KLK1, Hsap\KLK3, Hsap\TMPRSS11B, Hsap\PRSS48, Hsap\TMPRSS11D, Hsap\CTRB2, Hsap\PRSS21, Hsap\KLKB1, Hsap\CELA2B, Hsap\PRSS41, Hsap\C1R, Hsap\KLK2, Hsap\CELA2A, Hsap\CTRB1, Hsap\F11, Hsap\CELA3B, Hsap\KLK11, Hsap\CTRL, Hsap\CELA1, Hsap\CTRC, Hsap\CELA3A" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0051647 CR31647 - http://flybase.org/reports/FBgn0051647 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE16275, CG31647, CR31647" - CR31647 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016970 l(2)k10201 lethal (2) k10201 http://flybase.org/reports/FBgn0016970 "FBgn0033409, FBgn0033410" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 multicellular organism development ; GO:0007275 | inferred from mutant phenotype - "B, CG8803, CG13951, l(2)k10201" IPR013087:Zinc finger C2H2-type CG13951 11-Aug-17 DroID_v2017_08 Drer\znf511 - - - Mmus\Zfp511 Hsap\ZNF511 "lethal,recessive,wild-type,viable" FBgn0028892 CG4161 - http://flybase.org/reports/FBgn0028892 protein_coding_gene protein carboxyl O-methyltransferase activity ; GO:0051998 | inferred from sequence or structural similarity with HGNC:17872 protein methylation ; GO:0006479 | inferred from sequence or structural similarity with HGNC:17872 cellular_component ; GO:0005575 | no biological data available "BG:DS03023.2, CG4161" IPR002791:Domain of unknown function DUF89 CG4161 11-Aug-17 DroID_v2017_08 Drer\armt1 Scer\YMR027W Cele\F31D4.2 Xtro\armt1 Mmus\Armt1 Hsap\ARMT1 "partially lethal - majority die,some die during pupal stage" FBgn0260384 GSd464 - http://flybase.org/reports/FBgn0260384 gene - - - GSd464 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0014357 ms(2)HB441 ms(2)HB441 http://flybase.org/reports/FBgn0014357 - gene - - - ms(2)HB441 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032181 CG13133 - http://flybase.org/reports/FBgn0032181 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model cellular_component ; GO:0005575 | no biological data available "Dmel24.5, CG13133" "IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG13133 11-Aug-17 DroID_v2017_08 "Drer\hspb11, Drer\hspb2, Drer\hspb6, Drer\hspb7, Drer\hspb8, Drer\cryaa, Drer\cryaba, Drer\hspb3, Drer\hspb1, Drer\hspb15, Drer\si:dkey-1k23.3" - - "Xtro\hspb1, Xtro\cryaa, Xtro\hsp30d, Xtro\cryab, Xtro\hspb3, Xtro\uqcrh, Xtro\hspb6, Xtro\hspb8, Xtro\hspb2" "Mmus\Hspb2, Mmus\Hspb3, Mmus\Cryaa, Mmus\Cryab, Mmus\Hspb7, Mmus\Hspb6, Mmus\Hspb9, Mmus\Hspb8, Mmus\Hspb1" "Hsap\HSPB7, Hsap\CRYAA, Hsap\CRYAB, Hsap\HSPB9, Hsap\HSPB3, Hsap\HSPB2, Hsap\HSPB6, Hsap\HSPB1, Hsap\HSPB8" FBgn0010800 l(3)03471 lethal (3) 03471 http://flybase.org/reports/FBgn0010800 - gene - - - l(3)03471 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014207 l(1)17Ab lethal (1) 17Ab http://flybase.org/reports/FBgn0014207 - gene - - - "17516, l(1)17Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0060377 l(3)S135409 lethal (3) S135409 http://flybase.org/reports/FBgn0060377 gene - - - "1354/09, l(3)S135409" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0001576 l(1)3063 lethal (1) 3063 http://flybase.org/reports/FBgn0001576 - gene - - - l(1)3063 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0030494 Cpr12A Cuticular protein 12A http://flybase.org/reports/FBgn0030494 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:LP12385, Cpr12A, CG15757" IPR000618:Insect cuticle protein CG15757 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0264005 Hmx H6-like-homeobox http://flybase.org/reports/FBgn0264005 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q9NP08 "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q9NP08" - "CG43748, CG18139, Hmx, CG34419, DHmx, CG5832, CG5829" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR020479:Homeobox domain, metazoa, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site" CG43748 11-Aug-17 DroID_v2017_08 "Drer\pou5f3, Drer\pou2f3, Drer\hmx3a, Drer\hmx2, Drer\hmx1, Drer\hmx3b, Drer\hmx4, Drer\barhl1a" Scer\HMRA1 "Cele\mls-2, Cele\K11D12.11, Cele\K11D12.13, Cele\C06B8.11, Cele\Y49G5A.1, Cele\K11D12.7, Cele\nob-1, Cele\php-3, Cele\C10G8.3" "Xtro\hmx2, Xtro\hmx3, Xtro\hmx1" "Mmus\Hmx1, Mmus\Hmx3, Mmus\Hmx2" "Hsap\HMX3, Hsap\HMX1, Hsap\HMX2" FBgn0053282 CG33282 - http://flybase.org/reports/FBgn0053282 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "CG15407, CG33282" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG33282 11-Aug-17 DroID_v2017_08 "Drer\slc2a6, Drer\slc2a12, Drer\slc2a10, Drer\slc2a8, Drer\slc2a13b, Drer\LOC101882338" "Scer\HXT9, Scer\HXT13, Scer\DTR1, Scer\ITR2, Scer\GEX1, Scer\TPO4, Scer\HXT3, Scer\HXT11, Scer\TPO1, Scer\MAL11, Scer\ENB1, Scer\TPO2, Scer\VBA4, Scer\YHK8, Scer\HXT1, Scer\MPH2, Scer\ATR1, Scer\HXT10, Scer\YMR279C, Scer\VBA3, Scer\TPO3, Scer\YFL040W, Scer\GEX2, Scer\RGT2, Scer\VBA2, Scer\HXT17, Scer\YDR387C, Scer\ITR1, Scer\YDL199C, Scer\VBA5, Scer\HXT5, Scer\HXT14, Scer\AZR1, Scer\MPH3, Scer\HXT6, Scer\SGE1, Scer\FLR1, Scer\STL1, Scer\GAL2, Scer\HXT15, Scer\VBA1, Scer\HXT4, Scer\HXT2, Scer\HXT7, Scer\HXT16, Scer\MAL31, Scer\HXT8, Scer\SNF3" - "Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a12, Xtro\slc2a10" "Mmus\Slc2a6, Mmus\Slc2a10, Mmus\Slc2a12, Mmus\Slc2a8, Mmus\Slc2a13" "Hsap\SLC2A12, Hsap\SLC2A8, Hsap\SLC2A10, Hsap\SLC2A6, Hsap\SLC2A13" viable FBgn0082989 snoRNA:Psi28S-2442a snoRNA:Psi28S-2442a http://flybase.org/reports/FBgn0082989 snoRNA_gene - - - "snoRNA:Psi28S-2442a, psi28s-2442a, Psi 28S-2442a, CR34613" - CR34613 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032549 CG4650 - http://flybase.org/reports/FBgn0032549 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH197, CG4650" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG4650 11-Aug-17 DroID_v2017_08 - - Cele\try-3 - - - viable FBgn0011851 tRNA:Glu-CTC-3-4 transfer RNA:Glutamic acid-CTC 3-4 http://flybase.org/reports/FBgn0011851 "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052327, FBgn0060250" tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "AE002584.trna6-GluCTC, tRNA:E4, tRNA:E:CTC:AE002584-d, tRNA:glu4:62Aa, CR32327, tRNA:Glu, chr3L.trna6-GluCTC, tRNA:Glu-CTC-3-4, tRNA:E4:62Aa, tRNA-Glu-CTC-3-4, GAG" - CR32327 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262776 Su(E1)-J - http://flybase.org/reports/FBgn0262776 gene - - - Su(E1)-J - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053741 snmRNA:430:CR33741 snmRNA:430:CR33741 http://flybase.org/reports/FBgn0053741 non_protein_coding_gene - - - "CR33741, snmRNA:430:CR33741" - CR33741 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037769 CG12419 - http://flybase.org/reports/FBgn0037769 protein_coding_gene - - - CG12419 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0011097 l(1)Q57 lethal (1) Q57 http://flybase.org/reports/FBgn0011097 FBgn0010210 gene - - - l(1)Q57 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000194 bla bladderwing http://flybase.org/reports/FBgn0000194 - gene - - - bla - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,female,female sterile,lethal,maternal effect,recessive,male sterile,viable,male,reduced,male fertile" "wing,eye" FBgn0016827 l(1)MZ14 lethal (1) MZ14 http://flybase.org/reports/FBgn0016827 - gene - - - "l(1)MZ14, M14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266349 CR44998 - http://flybase.org/reports/FBgn0266349 non_protein_coding_gene - - - CR44998 - CR44998 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060416 l(3)S129515 lethal (3) S129515 http://flybase.org/reports/FBgn0060416 gene - - - "1295/15, l(3)S129515" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266231 CR44926 - http://flybase.org/reports/FBgn0266231 non_protein_coding_gene - - - "CR44926, lincRNA.685" - CR44926 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019764 l(1)5g11 lethal (1) 5g11 http://flybase.org/reports/FBgn0019764 - gene - - - l(1)5g11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045854 en(lz)Y en(lz)Y http://flybase.org/reports/FBgn0045854 gene - - - en(lz)Y - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0036024 CG18180 - http://flybase.org/reports/FBgn0036024 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP151, CG18180" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG18180 11-Aug-17 DroID_v2017_08 "Drer\zgc:112266, Drer\masp2" - - - "Mmus\C1s1, Mmus\C1s2" "Hsap\PROC, Hsap\C1S" viable FBgn0032724 CG10428 - http://flybase.org/reports/FBgn0032724 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000332307 CG10428 "IPR025714:Methyltransferase domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR010987:Glutathione S-transferase, C-terminal-like" CG10428 11-Aug-17 DroID_v2017_08 Drer\gstcd - - Xtro\gstcd Mmus\Gstcd Hsap\GSTCD FBgn0016960 tkv::tor tkv::tor http://flybase.org/reports/FBgn0016960 - engineered_fusion_gene - - - tkv::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065463 l(2)SH1357 lethal (2) SH1357 http://flybase.org/reports/FBgn0065463 gene - - - "l(2)SH1357, l(2)SH2 1357" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004982 Bld Blond http://flybase.org/reports/FBgn0004982 - gene - - - Bld - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,dominant" "macrochaeta,microchaeta" FBgn0004633 CAT-repeat CAT repeat http://flybase.org/reports/FBgn0004633 - repeat_region - - - CAT-repeat - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026305 anon-16Fd anon-16Fd http://flybase.org/reports/FBgn0026305 - gene - - - "HL-III, anon-16Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052636 CR32636 - http://flybase.org/reports/FBgn0052636 non_protein_coding_gene - - - "CG15746, CG32636, CR32636" - CR32636 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031701 TotM Turandot M http://flybase.org/reports/FBgn0031701 protein_coding_gene - defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern response to heat ; GO:0009408 | inferred from direct assay cellular response to heat ; GO:0034605 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence or structural similarity with TotA extracellular region ; GO:0005576 | inferred from sequence model "TotM, totM, tot, CG14027, Tot M, Turandot M, TOTM" IPR010825:Stress-inducible humoral factor Turandot CG14027 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0029877 CG17717 - http://flybase.org/reports/FBgn0029877 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT19932, CG17717" "IPR011016:Zinc finger, RING-CH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033275:E3 ubiquitin-protein ligase MARCH-like" CG17717 11-Aug-17 DroID_v2017_08 "Drer\march6, Drer\march7, Drer\zgc:158785, Drer\march2, Drer\march11, Drer\march8, Drer\march9, Drer\march4, Drer\zgc:153256" Scer\SSM4 "Cele\marc-6, Cele\marc-5, Cele\marc-4, Cele\marc-3, Cele\marc-1" "Xtro\march7, Xtro\march4, Xtro\march2, Xtro\march11, Xtro\march8, Xtro\march3, Xtro\march1, Xtro\march9" "Mmus\March6, Mmus\March3, Mmus\March1, Mmus\March10, Mmus\Hnrnpm, Mmus\March9, Mmus\March4, Mmus\March2, Mmus\March11, Mmus\March8" "Hsap\MARCH11, Hsap\MARCH9, Hsap\MARCH4, Hsap\MARCH1, Hsap\MARCH8, Hsap\MARCH10, Hsap\MARCH6, Hsap\MARCH7, Hsap\MARCH3, Hsap\MARCH2" FBgn0264727 CR43995 - http://flybase.org/reports/FBgn0264727 non_protein_coding_gene - - - CR43995 - CR43995 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029066 l(1)G0280 lethal (1) G0280 http://flybase.org/reports/FBgn0029066 gene - - - l(1)G0280 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025728 tra2::U2af50 tra2::U2af50 http://flybase.org/reports/FBgn0025728 - engineered_fusion_gene - - - "TRA-2/dU2AF[50], tra2::U2af50" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030056 CG11284 - http://flybase.org/reports/FBgn0030056 protein_coding_gene - - - "CG11284, CG11285" "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class" CG11284 11-Aug-17 DroID_v2017_08 "Drer\ca10b, Drer\ptprga, Drer\ca5a, Drer\ca2, Drer\ca15a, Drer\car15, Drer\ca7, Drer\ca14, Drer\cahz, Drer\ca12, Drer\ca9, Drer\si:ch211-173d10.4, Drer\ca4a, Drer\ca8, Drer\ca16b, Drer\ca10a, Drer\ca15b, Drer\ca6, Drer\ca4b, Drer\zgc:153760, Drer\ca4c, Drer\ca15c" - "Cele\cah-6, Cele\cah-4, Cele\cah-5, Cele\cah-3" "Xtro\ca7, Xtro\ca6, Xtro\car1_predicted, Xtro\ca11, Xtro\ca14, Xtro\ca2, Xtro\ca3, Xtro\ca12, Xtro\ca1, Xtro\ca10, Xtro\ca8, Xtro\ca5b, Xtro\ca4, Xtro\LOC779564" "Mmus\Car6, Mmus\Car5b, Mmus\Car5a, Mmus\Car2, Mmus\Car10, Mmus\Ptprg, Mmus\Car11, Mmus\Car12, Mmus\Car15, Mmus\Car1, Mmus\Car3, Mmus\Car8, Mmus\Car7, Mmus\Car13, Mmus\Car4, Mmus\Car9, Mmus\Car14" "Hsap\CA13, Hsap\PTPRG, Hsap\CA6, Hsap\CA3, Hsap\CA14, Hsap\CA5B, Hsap\CA8, Hsap\CA1, Hsap\CA4, Hsap\CA11, Hsap\CA7, Hsap\CA5A, Hsap\CA2, Hsap\CA12, Hsap\CA10, Hsap\CA9" viable FBgn0266734 CR45207 - http://flybase.org/reports/FBgn0266734 non_protein_coding_gene - - - CR45207 - CR45207 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262164 Z0189 - http://flybase.org/reports/FBgn0262164 gene - - - "Z0189, gene ; SO:0000704" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable photoreceptor cell R7 FBgn0002209 l(3)67BDg lethal (3) 67BDg http://flybase.org/reports/FBgn0002209 - gene - - - l(3)67BDg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020300 geko geko http://flybase.org/reports/FBgn0020300 "FBgn0036779, FBgn0040790, FBgn0047124" protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of smell ; GO:0007608 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CT33153, Geko, CG13696, CG13695, BcDNA:RE30284, geko, gk" - CG13695 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0050209 tRNA:Trp-CCA-2-6 transfer RNA:Tryptophan-CCA 2-6 http://flybase.org/reports/FBgn0050209 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "CR30209, AE002575.trna12-TrpCCA, tRNA:W:CCA:AE002575-c, chr2R.trna56-TrpCCA, tRNA-Trp-CCA-2-6, tRNA:Trp-CCA-2-6, tRNA:CR30209, UGG" - CR30209 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003728 tnt tent http://flybase.org/reports/FBgn0003728 - gene - - - tnt - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,visible" "macrochaeta,wing" FBgn0023453 ches chestnut http://flybase.org/reports/FBgn0023453 - gene - - - ches - - 11-Aug-17 DroID_v2017_08 - - - - - - visible pigment cell FBgn0004735 l(3)85Db lethal (3) 85Db http://flybase.org/reports/FBgn0004735 - gene - - - l(3)85Db - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051263 CG31263 - http://flybase.org/reports/FBgn0051263 protein_coding_gene - - - CG31263 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031161 CG15445 - http://flybase.org/reports/FBgn0031161 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG15445, NUB1" "IPR015940:Ubiquitin-associated domain, IPR009060:UBA-like, IPR029071:Ubiquitin-related domain" CG15445 11-Aug-17 DroID_v2017_08 "Drer\zgc:153057, Drer\nub1" - - Xtro\nub1 Mmus\Nub1 Hsap\NUB1 "viable,fertile,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0020564 anon-II-E9 anon-II-E9 http://flybase.org/reports/FBgn0020564 - gene - - - anon-II-E9 - - 11-Aug-17 DroID_v2017_08 - - - - - - Bolwig nerve FBgn0053177 CG33177 - http://flybase.org/reports/FBgn0053177 protein_coding_gene - - - "CG5579, CG33177" "IPR001129:Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein, IPR023352:Membrane associated eicosanoid/glutathione metabolism-like domain" CG33177 11-Aug-17 DroID_v2017_08 "Drer\mgst1.2, Drer\mgst1.1, Drer\ptges" - - "Xtro\mgst1, Xtro\ptges" "Mmus\Ptges, Mmus\Mgst1" "Hsap\MGST1, Hsap\PTGES" FBgn0061486 road regulator of armadillo http://flybase.org/reports/FBgn0061486 gene - - - road - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003647 Su(z)6 Suppressor of zeste 6 http://flybase.org/reports/FBgn0003647 - gene - - - Su(z)6 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile pigment cell FBgn0039043 CG17121 - http://flybase.org/reports/FBgn0039043 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - CG17121 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG17121 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-221h15.4, Drer\rdh20, Drer\sdr16c5a, Drer\rdh10a, Drer\sdr16c5b, Drer\dhrs3b, Drer\dhrs3a" "Scer\TDA5, Scer\YDL114W, Scer\YIR035C" "Cele\dhs-29, Cele\dhs-4" "Xtro\hsd17b13, Xtro\hsd17b11, Xtro\rdh10, Xtro\dhrs3, Xtro\sdr16c5" "Mmus\Sdr16c6, Mmus\Rdh10, Mmus\Hsd11b1, Mmus\Dhrs3, Mmus\Hsd17b11, Mmus\Hsd17b13, Mmus\Sdr16c5" "Hsap\HSD17B11, Hsap\HSD11B1L, Hsap\SDR16C5, Hsap\HSD17B13, Hsap\HSD11B1, Hsap\DHRS3, Hsap\RDH10" "partially lethal - majority die,some die during pupal stage" FBgn0051097 CG31097 - http://flybase.org/reports/FBgn0051097 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG13665, CG31097" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31097 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\T16G1.3, Cele\H06H21.8, Cele\C29F7.1, Cele\nhr-246, Cele\F59B1.10, Cele\F59B1.8, Cele\C29F7.2" - - - "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0065774 l(2)SH0456 lethal (2) SH0456 http://flybase.org/reports/FBgn0065774 gene - - - "l(2)SH0456, l(2)SH2 0456" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030421 CG3812 - http://flybase.org/reports/FBgn0030421 protein_coding_gene 1-acylglycerol-3-phosphate O-acyltransferase activity ; GO:0003841 | inferred from electronic annotation with InterPro:IPR004552 acylglycerol O-acyltransferase activity ; GO:0016411 | inferred from biological aspect of ancestor with PANTHER:PTN000046632 phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR004552 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR004552 proteasome complex ; GO:0000502 | colocalizes_with inferred from direct assay "CG3812, AGPAT2, AGPAT1" "IPR002123:Phospholipid/glycerol acyltransferase, IPR004552:1-acyl-sn-glycerol-3-phosphate acyltransferase" CG3812 11-Aug-17 DroID_v2017_08 "Drer\lpcat2, Drer\agpat2" Scer\SLC1 "Cele\acl-2, Cele\acl-1" "Xtro\agpat1, Xtro\agpat2" "Mmus\Agpat1, Mmus\Agpat2" "Hsap\AGPAT1, Hsap\AGPAT2" "viable,fertile" FBgn0061068 l(3)S018812b lethal (3) S018812b http://flybase.org/reports/FBgn0061068 gene - - - "0188/12, l(3)S018812b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022353 anon-25Da anon-25Da http://flybase.org/reports/FBgn0022353 - gene - - - "e1, anon-25Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014044 Su(tor)2-180 Su(tor)2-180 http://flybase.org/reports/FBgn0014044 - gene - - - Su(tor)2-180 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,semidominant" FBgn0262808 CG43179 - http://flybase.org/reports/FBgn0262808 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43179, chr3R_10081851_10082659.0" "IPR031986:Serine protease gd, N-terminal domain" CG43179 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010541 l(2)03497 lethal (2) 03497 http://flybase.net/reports/FBgn0010541.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0261454 scaRNA:MeU4-A65 small Cajal body-specific RNA : MeU4-A65 http://flybase.org/reports/FBgn0261454 snoRNA_gene snRNA 2'-O-ribose methylation guide activity ; GO:0030563 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "mgU4-65, scaRNA:CG7510-a, scaRNA:mgU4-65, scaRNA:MeU4-A65" - CR43571 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034802 CNBP CCHC-type zinc finger nucleic acid binding protein http://flybase.org/reports/FBgn0034802 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG11716, BEST:GM06241, anon-EST:fe1B4, anon-EST:fe2B6, CG3800, CNBP, dCNBP" "IPR001878:Zinc finger, CCHC-type" CG3800 11-Aug-17 DroID_v2017_08 "Drer\LOC100333474, Drer\zcchc9, Drer\zcchc14, Drer\si:ch1073-284b18.2, Drer\zcchc7, Drer\cnbpb, Drer\cnbpa" "Scer\AIR1, Scer\GIS2, Scer\AIR2" "Cele\F49F1.8, Cele\dct-10, Cele\K08D12.3, Cele\glh-1, Cele\glh-4" "Xtro\zcchc9, Xtro\zcchc7, Xtro\cnbp" "Mmus\Zcchc13, Mmus\Cnbp, Mmus\Zcchc9, Mmus\Zcchc14" "Hsap\ZCCHC13, Hsap\ZCCHC14, Hsap\CNBP, Hsap\ZCCHC9" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0085514 CG40754 - http://flybase.org/reports/FBgn0085514 protein_coding_gene - - - CG40754 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020443 eRF3 eukaryotic translation release factor 3 http://flybase.org/reports/FBgn0020443 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000561878 GTPase activity ; GO:0003924 | non-traceable author statement translation release factor activity ; GO:0003747 | non-traceable author statement GTP binding ; GO:0005525 | inferred from sequence or structural similarity translation termination factor activity ; GO:0008079 | inferred from sequence or structural similarity translation release factor activity ; GO:0003747 | inferred from biological aspect of ancestor with PANTHER:PTN000562411" cytoplasmic translational termination ; GO:0002184 | inferred from biological aspect of ancestor with PANTHER:PTN000562411 translational termination ; GO:0006415 | non-traceable author statement translational termination ; GO:0006415 | inferred from sequence or structural similarity translational termination ; GO:0006415 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay translation release factor complex ; GO:0018444 | inferred from biological aspect of ancestor with PANTHER:PTN000562411 cytosol ; GO:0005829 | inferred from sequence or structural similarity cytosol ; GO:0005829 | non-traceable author statement "eRF3, DSUP35, CG6382, Dsup35, dsup35, delf, Elf, elf" "IPR000795:Transcription factor, GTP-binding domain, IPR004160:Translation elongation factor EFTu/EF1A, C-terminal, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR009818:Ataxin-2, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031157:Tr-type G domain, conserved site" CG6382 11-Aug-17 DroID_v2017_08 "Drer\gspt1, Drer\gspt1l, Drer\hbs1l" "Scer\HBS1, Scer\SUP35" "Cele\K07A12.4, Cele\erfa-3" "Xtro\hbs1l, Xtro\gspt1" "Mmus\Gspt2, Mmus\Gspt1, Mmus\Hbs1l" "Hsap\GSPT1, Hsap\GSPT2" adult stage | male " testis

, spermatid

, spermatogonium

, spermatocyte

" "viable,fertile,lethal,recessive,male sterile,cytokinesis defective,lethal - all die before end of larval stage,some die during larval stage" "onion stage spermatid,Nebenkern,aster" FBgn0063407 l(3)3450-P lethal (3) 3450-P http://flybase.org/reports/FBgn0063407 gene - - - l(3)3450-P - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0020529 l(3)CB24 lethal (3) CB24 http://flybase.org/reports/FBgn0020529 - gene - - - l(3)CB24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031832 CG9596 - http://flybase.org/reports/FBgn0031832 protein_coding_gene - tRNA methylation ; GO:0030488 | inferred from electronic annotation with InterPro:IPR017423 lateral inhibition ; GO:0046331 | inferred from mutant phenotype tRNA (m1A) methyltransferase complex ; GO:0031515 | inferred from electronic annotation with InterPro:IPR017423 CG9596 IPR017423:tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 CG9596 11-Aug-17 DroID_v2017_08 Drer\trmt6 Scer\GCD10 Cele\ZK858.7 Xtro\trmt6 Mmus\Trmt6 Hsap\TRMT6 "viable,fertile,visible" "chaeta,trichogen cell" FBgn0025355 SuUR Suppressor of Under-Replication http://flybase.org/reports/FBgn0025355 FBgn0036120 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay chromosome organization ; GO:0051276 | inferred from mutant phenotype heterochromatin assembly ; GO:0031507 | inferred from mutant phenotype positive regulation of DNA endoreduplication ; GO:0032877 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from expression pattern chromatin assembly or disassembly ; GO:0006333 | inferred from expression pattern DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype negative regulation of DNA replication ; GO:0008156 | traceable author statement "polytene chromosome ; GO:0005700 | traceable author statement nuclear telomeric heterochromatin ; GO:0005724 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay heterochromatin ; GO:0000792 | traceable author statement intercalary heterochromatin ; GO:0005725 | inferred from direct assay pericentric heterochromatin ; GO:0005721 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | traceable author statement" "su(UR)ES, Su(UR), Su(UR)ES, CG7869, SuUR, SUUR, Dromel_CG7869_FBtr0076203_suur_mORF, SU(UR)" IPR027417:P-loop containing nucleoside triphosphate hydrolase CG7869 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,suppressor of variegation,dominant,enhancer of variegation,wild-type,female sterile,partially,female fertile,size defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "polytene chromosomeSgs3.PD,polytene chromosome & salivary gland | conditional - heat sensitiveSgs3.PD,intercalary heterochromatinSgs3.PD,embryonic/larval salivary gland,polytene chromosome weak point,intercalary heterochromatin,polytene chromosome band,polytene chromosome,heterochromatin,beta-heterochromatin,alpha-heterochromatin,polytene chromosome band & salivary gland | ectopic,polytene chromosomeAB1,salivary gland" FBgn0267580 CR45920 - http://flybase.org/reports/FBgn0267580 non_protein_coding_gene - - - "CR45920, pri-mir-316" - CR45920 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030794 CG13005 - http://flybase.org/reports/FBgn0030794 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13005 - CG13005 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264435 CR43853 - http://flybase.org/reports/FBgn0264435 non_protein_coding_gene - - - "CR43853, lincRNA.142" - CR43853 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004488 l(1)air15 lethal aberrant immune response 15 http://flybase.org/reports/FBgn0004488 - gene - - - "air15, l(1)air[15], l(1)air15" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "embryonic/larval brain,melanotic mass,embryonic/larval lymph gland" FBgn0020415 Idgf2 Imaginal disc growth factor 2 http://flybase.org/reports/FBgn0020415 FBgn0027923 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 imaginal disc growth factor receptor binding ; GO:0008084 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 imaginal disc development ; GO:0007444 | inferred from direct assay" extracellular region ; GO:0005576 | non-traceable author statement extracellular region ; GO:0005576 | inferred from direct assay "CG4475, IDGF2, IDGF-2, idgf2, BG:DS02780.4, IDGF, Idgf2, DmIDGF2" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG4475 11-Aug-17 DroID_v2017_08 "Drer\chia.3, Drer\ovgp1, Drer\chia.5, Drer\chia.4, Drer\chia.2, Drer\si:ch211-226m16.2, Drer\chia.6" Scer\CTS2 "Cele\chil-4, Cele\chil-23, Cele\chil-22, Cele\chil-2, Cele\chil-16, Cele\lmd-4, Cele\chil-11, Cele\chil-8, Cele\lmd-5, Cele\chil-13, Cele\chil-17, Cele\chil-6, Cele\T19H5.6, Cele\chil-18, Cele\chil-25, Cele\chil-15, Cele\chil-12, Cele\cht-2, Cele\chil-19, Cele\chil-20, Cele\chil-24, Cele\chil-7, Cele\chil-3, Cele\chil-5" "Xtro\chit1, Xtro\chia, Xtro\LOC548945, Xtro\ctbs" "Mmus\Chil6, Mmus\Chil3, Mmus\Chil4, Mmus\Ovgp1, Mmus\Chia1, Mmus\Chil5, Mmus\Chit1, Mmus\Ctbs, Mmus\Chil1" "Hsap\CHI3L1, Hsap\CHI3L2, Hsap\CHIA, Hsap\CHIT1, Hsap\OVGP1" " embryonic stage , larval stage | third instar , embryonic stage && larval stage , adult stage && oogenesis stage " " yolk

, lymph gland

, embryonic/larval salivary gland

, ventral furrow | vicinity of

, oocyte

, embryonic/larval fat body

, imaginal disc

, amnioproctodeal invagination | vicinity of

, embryonic/larval tracheal system

, cephalic furrow | vicinity of

, nurse cell

, ring gland

, larval brain

, larval optic lobe

" FBgn0029105 alpha-Catr alpha-catenin related http://flybase.org/reports/FBgn0029105 protein_coding_gene actin filament binding ; GO:0051015 | inferred from electronic annotation with InterPro:IPR006077 actin binding ; GO:0003779 | inferred from sequence or structural similarity cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR006077 Rho protein signal transduction ; GO:0007266 | inferred from electronic annotation with InterPro:IPR030045 - "alpha-catenin-Related, CG2987, alpha-Catr, alpha-catenin-related" "IPR030045:Alpha-catulin 1, IPR006077:Vinculin/alpha-catenin" CG2987 11-Aug-17 DroID_v2017_08 "Drer\ctnnal1, Drer\tmem245, Drer\ctnna2, Drer\ctnna1" - Cele\ctn-1 "Xtro\vcl, Xtro\ctnna1, Xtro\ctnnal1" "Mmus\Ctnnal1, Mmus\Ctnna1, Mmus\Ctnna3, Mmus\Vcl, Mmus\Ctnna2, Mmus\Tmem245, Mmus\Gm14025" "Hsap\CTNNA3, Hsap\CTNNA1, Hsap\CTNNA2, Hsap\VCL, Hsap\CTNNAL1" viable FBgn0004800 fs(2)ltoQZ47 female sterile (2) ltoQZ47 http://flybase.org/reports/FBgn0004800 - gene molecular_function ; GO:0003674 | no biological data available ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoQZ47 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0026653 l(2)3A2 lethal (2) 3A2 http://flybase.org/reports/FBgn0026653 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)3A2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0052488 CG32488 - http://flybase.org/reports/FBgn0052488 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with SGD:S000002395 phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000002395 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002395 dephosphorylation ; GO:0016311 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002395 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002395 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000445812 "CG2077, CG32488, Phos32488, 20151345" "IPR006349:2-phosphoglycolate phosphatase, eukaryotic, IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG32488 11-Aug-17 DroID_v2017_08 "Drer\gbas, Drer\pdxp, Drer\pgp, Drer\nipsnap1" Scer\PHO13 "Cele\K09H11.7, Cele\F44E7.2, Cele\K02D10.1, Cele\C45E5.1, Cele\C53A3.2" Xtro\nipsnap1 "Mmus\Gbas, Mmus\Nipsnap1, Mmus\Pdxp, Mmus\Pgp" "Hsap\PDXP, Hsap\GBAS, Hsap\NIPSNAP1, Hsap\PGP" FBgn0037332 Hcs Holocarboxylase synthetase http://flybase.org/reports/FBgn0037332 protein_coding_gene biotin-[acetyl-CoA-carboxylase] ligase activity ; GO:0004077 | inferred from electronic annotation with InterPro:IPR004408 histone biotinylation ; GO:0071110 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype peptidyl-lysine biotinylation ; GO:0018054 | inferred from mutant phenotype polytene chromosome ; GO:0005700 | inferred from direct assay "HCS, NEST:bs27h05, Hcs, CG14670, HSC" "IPR003142:Biotin protein ligase, C-terminal, IPR004143:Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain, IPR004408:Biotin--acetyl-CoA-carboxylase ligase, IPR019197:Biotin-protein ligase, N-terminal" CG14670 11-Aug-17 DroID_v2017_08 Drer\hlcs Scer\BPL1 Cele\bpl-1 Xtro\hlcs Mmus\Hlcs Hsap\HLCS "short lived,heat stress response defective,male,female,viable,fertile" FBgn0053156 CG33156 - http://flybase.org/reports/FBgn0053156 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from sequence or structural similarity with SGD:S000003810 NAD metabolic process ; GO:0019674 | inferred from electronic annotation with InterPro:IPR017437 NADP biosynthetic process ; GO:0006741 | inferred from sequence or structural similarity with SGD:S000003810 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000003810 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003810 "CG30063, CG6152, CG33156" "IPR002504:NAD kinase, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR017437:ATP-NAD kinase, PpnK-type, all-beta, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG33156 11-Aug-17 DroID_v2017_08 "Drer\nadka, Drer\nadkb" "Scer\POS5, Scer\YEF1, Scer\UTR1" Cele\Y77E11A.2 Xtro\nadk Mmus\Nadk Hsap\NADK viable FBgn0021800 Reph Regulator of eph expression http://flybase.org/reports/FBgn0021800 FBgn0031572 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype ephrin receptor signaling pathway ; GO:0048013 | inferred from genetic interaction with Eph, Ephrin" cellular_component ; GO:0005575 | no biological data available "CG3920, Reph, reph, l(2)k16918" - CG3920 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,lethal,recessive,viable,fertile,visible" "commissure,longitudinal connective,medulla neuropil | third instar larval stage,lamina furrow,cell autonomous,somatic clone,mesothoracic tergum" FBgn0038958 CG13857 - http://flybase.org/reports/FBgn0038958 protein_coding_gene - - - CG13857 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR031983:Protein of unknown function DUF4786" CG13857 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060327 l(3)S146508 lethal (3) S146508 http://flybase.org/reports/FBgn0060327 gene - - - "1465/08, l(3)S146508" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0263975 CR43727 - http://flybase.org/reports/FBgn0263975 pseudogene_attribute - - - CR43727 - CR43727 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002975 ny notchy http://flybase.org/reports/FBgn0002975 - gene - - - ny - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,cold sensitive" "wing,cold sensitive" FBgn0023049 l(1)3An lethal (1) 3An http://flybase.org/reports/FBgn0023049 - gene - - - "C3/47.16, l(1)3An" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027578 CG14526 - http://flybase.org/reports/FBgn0027578 FBgn0039614 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" extracellular region ; GO:0005576 | inferred from direct assay "BcDNA:GH07188, CG14526" "IPR030082:Neprilysin-21, IPR024079:Metallopeptidase, catalytic domain, IPR018497:Peptidase M13, C-terminal domain, IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain" CG14526 11-Aug-17 DroID_v2017_08 "Drer\mmel1, Drer\ece2b, Drer\phex, Drer\ece1" - "Cele\nep-26, Cele\nep-11, Cele\nep-18, Cele\nep-6, Cele\nep-19, Cele\nep-9, Cele\nep-21, Cele\nep-17, Cele\nep-24, Cele\nep-16, Cele\nep-23, Cele\nep-20, Cele\nep-12, Cele\nep-3, Cele\nep-1, Cele\nep-7, Cele\nep-5, Cele\nep-8, Cele\nep-13, Cele\nep-10" "Xtro\ecel1, Xtro\ece1, Xtro\mmel1, Xtro\ece2" "Mmus\Ece1, Mmus\Ece2, Mmus\Mmel1, Mmus\Phex, Mmus\Kel, Mmus\Mme, Mmus\Ecel1" "Hsap\ECE1, Hsap\ECE2, Hsap\MMEL1, Hsap\MME, Hsap\KEL, Hsap\ECEL1, Hsap\PHEX" viable FBgn0014237 l(2)31Et lethal (2) 31Et http://flybase.org/reports/FBgn0014237 - gene - - - l(2)31Et - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004983 bleg black leg http://flybase.org/reports/FBgn0004983 - gene - - - bleg - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,body color defective" "leg,wing" FBgn0039271 CG11839 - http://flybase.org/reports/FBgn0039271 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from biological aspect of ancestor with PANTHER:PTN000328334 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000328334 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:28291 "CT36969, CG11839, Znf830" - CG11839 11-Aug-17 DroID_v2017_08 Drer\zgc:77398 - Cele\sel-13 Xtro\znf830 Mmus\Zfp830 Hsap\ZNF830 "viable,neurophysiology defective" embryonic/larval neuromuscular junction | larval stage FBgn0038033 CG10097 - http://flybase.org/reports/FBgn0038033 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - "CT28427, CG32919, anon-WO0140519.58, CG10097" "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG10097 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-97m3.1, Drer\far1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far1, Mmus\Far2" "Hsap\FAR1, Hsap\FAR2" "viable,fertile" FBgn0005326 Osw Outspreadwing http://flybase.org/reports/FBgn0005326 - gene - - - Osw - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0267890 CR46178 - http://flybase.org/reports/FBgn0267890 pseudogene_attribute - - - "CR46178, CG12717-related" - CR46178 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053371 5SrRNA-Psi:CR33371 5SrRNA-Psi:CR33371 http://flybase.org/reports/FBgn0053371 pseudogene_attribute - - - "CR33371, 5SrRNA-Psi:CR33371" - CR33371 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267687 CR46023 - http://flybase.org/reports/FBgn0267687 non_protein_coding_gene - - - CR46023 - CR46023 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065700 l(2)SH0623 lethal (2) SH0623 http://flybase.org/reports/FBgn0065700 gene - - - "l(2)SH0623, l(2)SH2 0623" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002855 Acp26Aa Accessory gland protein 26Aa http://flybase.org/reports/FBgn0002855 - protein_coding_gene identical protein binding ; GO:0042802 | inferred from physical interaction with Acp26Aa mating ; GO:0007618 | inferred from electronic annotation with InterPro:IPR004315 sperm competition ; GO:0046692 | traceable author statement ovulation ; GO:0030728 | traceable author statement regulation of post-mating oviposition ; GO:0048042 | traceable author statement multicellular organism reproduction ; GO:0032504 | inferred from expression pattern oviposition ; GO:0018991 | traceable author statement post-mating behavior ; GO:0045297 | non-traceable author statement ovulation ; GO:0030728 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "Acp26A, Ovulin, Acp26Aab, Mst26Aa, Mst26A, mst 355a, mst355a, msP355a, CG8982, Acp26Aa, Acp26a, Acp, ovulin" IPR004315:Male Drosophila accessory gland secretory protein CG8982 11-Aug-17 DroID_v2017_08 - - Cele\Y41C4A.7 - - - " adult stage | male , pupal stage&&adult stage " male accessory gland

" adult stage | female , adult stage | male " " genital chamber

, adult hemolymph

, male accessory gland secondary cell

, male accessory gland

, male accessory gland main cell

" "viable,fertile" "egg,supernumerary" FBgn0039851 mey morpheyus http://flybase.org/reports/FBgn0039851 protein_coding_gene - apical constriction ; GO:0003383 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model "mey, CG12063" "IPR001507:Zona pellucida domain, IPR003609:PAN/Apple domain" CG12063 11-Aug-17 DroID_v2017_08 - - "Cele\C16D9.1, Cele\F52C9.5, Cele\ZC449.2, Cele\R07A4.4, Cele\C34C12.7, Cele\H03E18.1, Cele\cutl-28, Cele\cutl-27, Cele\noah-1, Cele\T23F1.5, Cele\cutl-17, Cele\T26C5.2, Cele\noah-2, Cele\H42K12.3, Cele\F32B4.8, Cele\cutl-18, Cele\let-653, Cele\ZC449.1" - - - FBgn0265895 CR44684 - http://flybase.org/reports/FBgn0265895 non_protein_coding_gene - - - CR44684 - CR44684 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061072 l(3)S017014a lethal (3) S017014a http://flybase.org/reports/FBgn0061072 gene - - - "0170/14, l(3)S017014a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035699 CG13300 - http://flybase.org/reports/FBgn0035699 protein_coding_gene - - - CG13300 - CG13300 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0063597 CS3-2 "Calcineurin suppressor, chromosome 3, group 2" http://flybase.org/reports/FBgn0063597 gene - - - CS3-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020579 anon-59Cf anon-59Cf http://flybase.org/reports/FBgn0020579 - gene - - - anon-59Cf - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043535 Obp57a Odorant-binding protein 57a http://flybase.org/reports/FBgn0043535 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush transport ; GO:0006810 | non-traceable author statement sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "Obp57c, 57a, OBP57a, Obp-f, anon-AE003792.1, CG30141, Obp57a, DmelObp57a, obp57a" IPR006170:Pheromone/general odorant binding protein CG30141 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0023187 Mabfb45 Monoclonal antibody fb45 http://flybase.org/reports/FBgn0023187 - gene - - - "MAB fb45, Mabfb45" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005694 Aef1 Adult enhancer factor 1 http://flybase.org/reports/FBgn0005694 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "AEF-1, CG5683, Aef1, AEF1" IPR013087:Zinc finger C2H2-type CG5683 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-210j14.3, Drer\zgc:171901, Drer\znf1113" "Scer\CMR3, Scer\YPR015C" "Cele\Y55F3AM.14, Cele\K11D2.4, Cele\B0310.2, Cele\M03D4.4" Xtro\znf665 Mmus\Zfp637 Hsap\ZNF32 "viable,fertile" FBgn0005366 Va Venae abnormels http://flybase.org/reports/FBgn0005366 - gene - - - Va - - 11-Aug-17 DroID_v2017_08 - - - - - - wing vein FBgn0062682 EP1570 EP1570 http://flybase.org/reports/FBgn0062682 gene - - - "EP(X)1570, EP1570" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267460 CR45810 - http://flybase.org/reports/FBgn0267460 non_protein_coding_gene - - - CR45810 - CR45810 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259974 Sfp84E Seminal fluid protein 84E http://flybase.org/reports/FBgn0259974 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp84E, CG42484" - CG42484 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061509 l(2)24Aa lethal (2) 24Aa http://flybase.org/reports/FBgn0061509 gene - - - l(2)24Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032291 CG17118 - http://flybase.org/reports/FBgn0032291 protein_coding_gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - CG17118 IPR007714:Cilia/flagella-associated protein 20/WDR90/C3orf67 CG17118 11-Aug-17 DroID_v2017_08 "Drer\cfap20, Drer\zgc:162324, Drer\wdr90" - Cele\C54C6.6 Xtro\wdr90 "Mmus\4930452B06Rik, Mmus\Cfap20, Mmus\Wdr90" "Hsap\C3orf67, Hsap\CFAP20, Hsap\WDR90" "viable,fertile" FBgn0262178 mir-981 mir-981 stem loop http://flybase.org/reports/FBgn0262178 miRNA_gene - - - "miR-981, dme-mir-981, mir-981, CR42885" - CR42885 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,lethal - all die before end of pupal stage,some die during pupal stage" "eye,wing disc,wing,wing margin,1st posterior cell" FBgn0030892 CG7206 - http://flybase.org/reports/FBgn0030892 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "transcription, DNA-templated ; GO:0006351 | inferred from biological aspect of ancestor with PANTHER:PTN002313313" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN002313313 CG7206 "IPR002716:PIN domain, IPR029060:PIN domain-like" CG7206 11-Aug-17 DroID_v2017_08 Drer\swt1 Scer\SWT1 "Cele\smg-6, Cele\ZK1248.15" - "Mmus\Swt1, Mmus\Smg6" "Hsap\SWT1, Hsap\SMG6" viable FBgn0265939 CR44726 - http://flybase.org/reports/FBgn0265939 non_protein_coding_gene - - - "lincRNA.127, CR44726" - CR44726 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002453 l(3)SG6 lethal (3) SG6 http://flybase.org/reports/FBgn0002453 - gene - - - l(3)SG6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0039118 CG10208 - http://flybase.org/reports/FBgn0039118 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT28701, CG10208" IPR018959:Domain of unknown function DUF1989 CG10208 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0010388 Dro Drosocin http://flybase.org/reports/FBgn0010388 "FBgn0062947, FBgn0067904" protein_coding_gene - defense response to bacterium ; GO:0042742 | non-traceable author statement defense response ; GO:0006952 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay antibacterial humoral response ; GO:0019731 | inferred from expression pattern positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from direct assay defense response to bacterium ; GO:0042742 | traceable author statement response to bacterium ; GO:0009617 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay "Dro, 143609_at, Drc, DROC, drosocin, DIM-15, drc, Dros, CG10816, dro, DIM 11, DIM 9, DIM 15, BcDNA:RH31634, IM15, Dro1, Drs, dros" - CG10816 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC07406 K 0.408037513 0.207729541 0.773140263 -0.313391777 2.727205213 0.473020341 FBgn0038258 CG7362 - http://flybase.org/reports/FBgn0038258 protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 potassium ion binding ; GO:0030955 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 pyruvate kinase activity ; GO:0004743 | inferred from biological aspect of ancestor with PANTHER:PTN000212670" glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 phagocytosis ; GO:0006909 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 CG7362 "IPR015795:Pyruvate kinase, C-terminal, IPR015813:Pyruvate/Phosphoenolpyruvate kinase-like domain, IPR001697:Pyruvate kinase, IPR015793:Pyruvate kinase, barrel, IPR018209:Pyruvate kinase, active site" CG7362 11-Aug-17 DroID_v2017_08 "Drer\pkmb, Drer\pkma, Drer\pklr" "Scer\PYK2, Scer\CDC19" "Cele\pyk-1, Cele\pyk-2" "Xtro\pklr, Xtro\pkm" "Mmus\Pklr, Mmus\Pkm" "Hsap\PKM, Hsap\PKLR" viable FBgn0259722 CG42376 - http://flybase.org/reports/FBgn0259722 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from electronic annotation with InterPro:IPR003213 - mitochondrion ; GO:0005739 | inferred from electronic annotation with InterPro:IPR003213 CG42376 "IPR003213:Cytochrome c oxidase, subunit VIb" CG42376 11-Aug-17 DroID_v2017_08 "Drer\coa6, Drer\cox6b2, Drer\cox6b1" "Scer\COA6, Scer\COX12" Cele\ZC434.7 "Xtro\cox6b1, Xtro\coa6" "Mmus\Coa6, Mmus\Cox6b2, Mmus\Cox6b1" "Hsap\COX6B1, Hsap\COX6B2, Hsap\COA6" FBgn0030973 CG7332 - http://flybase.org/reports/FBgn0030973 protein_coding_gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7332 "IPR011992:EF-hand domain pair, IPR025257:Domain of unknown function DUF4205" CG7332 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-30h22.11, Drer\fam188a" - - "Xtro\fam188a, Xtro\fam188b" "Mmus\Fam188a, Mmus\Fam188b" "Hsap\FAM188A, Hsap\FAM188B" viable FBgn0084653 Su(dpp)YE5 Su(dpp)YE5 http://flybase.org/reports/FBgn0084653 gene - - - Su(dpp)YE5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "denticle belt,amnioserosa" FBgn0017550 Rga Regena http://flybase.org/reports/FBgn0017550 FBgn0010819 protein_coding_gene poly(A)-specific ribonuclease activity ; GO:0004535 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs mRNA catabolic process ; GO:0006402 | inferred from direct assay nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | inferred from biological aspect of ancestor with PANTHER:PTN000595684" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR007282 nucleus ; GO:0005634 | non-traceable author statement CCR4-NOT complex ; GO:0030014 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 cytoplasm ; GO:0005737 | inferred from direct assay CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 "NOT2, CG2138, l(3)03834, CG2161, Rga, not2, Not2, RGA" IPR007282:NOT2/NOT3/NOT5 CG2161 11-Aug-17 DroID_v2017_08 Drer\cnot2 Scer\CDC36 "Cele\tag-153, Cele\ntl-2" Xtro\cnot2 Mmus\Cnot2 Hsap\CNOT2 "lethal,viable,fertile,partially lethal - majority die,recessive,visible,lethal - all die before end of larval stage,some die during larval stage,suppressor of variegation,dominant" "terminalia,chaeta,supernumerary" FBgn0266899 CR45359 - http://flybase.org/reports/FBgn0266899 non_protein_coding_gene - - - CR45359 - CR45359 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016054 phr6-4 (6-4)-photolyase http://flybase.org/reports/FBgn0016054 - protein_coding_gene - - - "38D.25, Dm 64, D6-4, phr(6-4), 64PHR, CG2488, phr6-4" "IPR005101:Cryptochrome/DNA photolyase, FAD-binding domain, IPR006050:DNA photolyase, N-terminal, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG2488 11-Aug-17 DroID_v2017_08 "Drer\zgc:66475, Drer\cry1bb, Drer\cry-dash, Drer\cry4, Drer\cry1ba, Drer\cry5, Drer\cry1aa, Drer\si:ch1073-390k14.1, Drer\cry2, Drer\cry1ab" Scer\PHR1 - "Xtro\LOC100144974, Xtro\cry4, Xtro\cry1, Xtro\cry2" "Mmus\Cry2, Mmus\Cry1" "Hsap\CRY2, Hsap\CRY1" adult stage && oogenesis stage ovary

viable FBgn0004588 Eig71Ea Ecdysone-induced gene 71Ea http://flybase.org/reports/FBgn0004588 - protein_coding_gene - metamorphosis ; GO:0007552 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 extracellular region ; GO:0005576 | inferred from sequence model "L71-1, L71, I, gene I, gene-I, CG16931, Eig71Ea" IPR003475:Insect protein of unknown function CG16931 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0082578 EP917 BEST:RE29262 http://flybase.org/reports/FBgn0082578 gene - - - "EP917, BEST:RE29262" - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0000884 fs(1)M82 female sterile (1) M82 http://flybase.org/reports/FBgn0000884 - gene - - - fs(1)M82 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0267731 CR46062 - http://flybase.org/reports/FBgn0267731 non_protein_coding_gene - - - CR46062 - CR46062 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082373 EP2031 EP2031 http://flybase.org/reports/FBgn0082373 gene - - - EP2031 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0061498 l(2)45Ao lethal (2) 45Ao http://flybase.org/reports/FBgn0061498 gene - - - l(2)45Ao - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031998 SLC5A11 Sodium/solute co-transporter-like 5A11 http://flybase.org/reports/FBgn0031998 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 behavioral response to nutrient ; GO:0051780 | inferred from mutant phenotype adult feeding behavior ; GO:0008343 | inferred from mutant phenotype "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "CG8451, CG8451-PA, SLC5A11" IPR001734:Sodium/solute symporter CG8451 11-Aug-17 DroID_v2017_08 "Drer\slc5a8, Drer\slc5a5, Drer\slc5a1, Drer\slc5a12, Drer\slc5a11, Drer\slc5a8l, Drer\slc5a3a, Drer\si:dkeyp-9d4.5, Drer\LOC568338, Drer\slc5a9, Drer\slc5a6a, Drer\slc5a6b, Drer\slc5a2" Scer\DUR3 "Cele\ZK822.5, Cele\F52H2.4" "Xtro\slc5a8, Xtro\slc5a1.1, Xtro\slc5a9, Xtro\slc5a11, Xtro\slc5a2, Xtro\slc5a5, Xtro\slc5a12" "Mmus\Slc5a1, Mmus\Slc5a11, Mmus\Gm5134, Mmus\Slc5a4b, Mmus\Slc5a5, Mmus\Slc5a3, Mmus\Slc5a12, Mmus\Slc5a8, Mmus\Slc5a9, Mmus\Slc5a4a, Mmus\Slc5a6, Mmus\Slc5a10, Mmus\Slc5a2" "Hsap\SLC5A2, Hsap\SLC5A1, Hsap\SLC5A4, Hsap\SLC5A8, Hsap\SLC5A5, Hsap\SLC5A3, Hsap\SLC5A6, Hsap\SLC5A9, Hsap\SLC5A12, Hsap\SLC5A10, Hsap\SLC5A11" "feeding behavior defective,chemical resistant,short lived,viable" FBgn0038165 Task6 TWIK-related acid-sensitive K[+] channel 6 http://flybase.org/reports/FBgn0038165 protein_coding_gene potassium channel activity ; GO:0005267 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Task7 potassium ion transmembrane transport ; GO:0071805 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "anon-WO0109301.60, anon-WO0109301.59, anon-WO0109301.58, anon-WO0109301.57, anon-WO0109301.56, anon-WO0109301.55, anon-WO0109301.54, anon-WO0109301.53, anon-WO0109301.11, CG9637, Task6, K2P-TASK6, dTASK-6" "IPR003092:Two pore domain potassium channel, TASK family, IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG9637 11-Aug-17 DroID_v2017_08 "Drer\kcnk15, Drer\kcnk3b, Drer\kcnk9, Drer\kcnk10a, Drer\kcnk12l, Drer\kcnk13b, Drer\kcnk18, Drer\kcnk12, Drer\kcnk3a, Drer\kcnk13a" Scer\TOK1 "Cele\sup-9, Cele\twk-20, Cele\twk-7" "Xtro\kcnk15, Xtro\kcnk12" "Mmus\Kcnk2, Mmus\Kcnk9, Mmus\Kcnk3, Mmus\Kcnk10, Mmus\Kcnk18, Mmus\Kcnk15, Mmus\Kcnk13, Mmus\Kcnk12" "Hsap\KCNK15, Hsap\KCNK3, Hsap\KCNK2, Hsap\KCNK10, Hsap\KCNK12, Hsap\KCNK13, Hsap\KCNK9, Hsap\KCNK18" "visible,partially lethal - majority die,some die during pupal stage,lethal" mesothoracic tergum FBgn0265346 CR44300 - http://flybase.org/reports/FBgn0265346 non_protein_coding_gene - - - CR44300 - CR44300 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027079 ValRS Valyl-tRNA synthetase http://flybase.org/reports/FBgn0027079 "FBgn0010542, FBgn0010671, FBgn0033805, FBgn0043789" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002300, InterPro:IPR002303, InterPro:IPR009080, InterPro:IPR019499 aminoacyl-tRNA editing activity ; GO:0002161 | inferred from electronic annotation with InterPro:IPR009008 valine-tRNA ligase activity ; GO:0004832 | traceable author statement glutamate-tRNA ligase activity ; GO:0004818 | inferred from sequence or structural similarity valine-tRNA ligase activity ; GO:0004832 | inferred from biological aspect of ancestor with PANTHER:PTN000236067" valyl-tRNA aminoacylation ; GO:0006438 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype valyl-tRNA aminoacylation ; GO:0006438 | inferred from biological aspect of ancestor with PANTHER:PTN000236067 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR019499 cytoplasm ; GO:0005737 | traceable author statement "l(2)03531, ValRS, VRS, l(2)rI255, ld45671, BEST:LD45671, CG4062, Aats-val, aats-val" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002300:Aminoacyl-tRNA synthetase, class Ia, IPR002303:Valine-tRNA ligase, IPR009008:Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR013155:Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR019499:Valyl-tRNA synthetase, tRNA-binding arm, IPR033705:Valyl tRNA synthetase, anticodon-binding domain" CG4062 11-Aug-17 DroID_v2017_08 "Drer\vars, Drer\vars2" Scer\VAS1 "Cele\vars-1, Cele\glp-4" "Xtro\vars, Xtro\vars2" "Mmus\Vars, Mmus\Vars2" "Hsap\VARS, Hsap\VARS2" embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0002815 ms(2)1 male sterile (2) 1 http://flybase.org/reports/FBgn0002815 - gene - - - ms(2)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female fertile" spermatozoon FBgn0020654 Mucin-D Mucin-D http://flybase.org/reports/FBgn0020654 - gene - - extracellular region ; GO:0005576 | inferred from direct assay female germline ring canal outer rim ; GO:0035182 | inferred from direct assay intercellular bridge ; GO:0045171 | inferred from direct assay female germline ring canal ; GO:0035324 | male germline ring canal ; GO:0035323 | "GP, Mucin-D, Gp90" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002925 ncn nurse cell number http://flybase.org/reports/FBgn0002925 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "ncn-I, ncn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,tumorigenic" "nurse cell,egg,egg chamber" FBgn0019851 anon-XIII anon-XIII http://flybase.org/reports/FBgn0019851 - gene - - - "XIII, anon-XIII" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041844 E(Sev-CycE)D45 E(Sev-CycE)D45 http://flybase.org/reports/FBgn0041844 gene - - - E(Sev-CycE)D45 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267007 CR45451 - http://flybase.org/reports/FBgn0267007 non_protein_coding_gene - - - CR45451 - CR45451 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0283462 IMPPP Immune induced molecule prepropeptide http://flybase.org/reports/FBgn0283462 protein_coding_gene molecular_function ; GO:0003674 | no biological data available Toll signaling pathway ; GO:0008063 | non-traceable author statement antibacterial humoral response ; GO:0019731 | inferred from direct assay defense response ; GO:0006952 | inferred from direct assay humoral immune response ; GO:0006959 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "IMPPP, CG18279, DIM 10, DIM 12, DIM 13, DIM 24, DIM 5, DIM 6, DIM 8, DIM 20, IM10, DIM10, DIM12, DIM13, DIM-10, DIM-12, DIM-13, DIM-24, im10, IM5, IM6, IM8, IM20" - CG18279 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0063365 EP853 BEST:RE60986 http://flybase.org/reports/FBgn0063365 gene - - - "RE60986, EP(2)0853, EP853, BEST:RE60986" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016659 H1 haemolymph protein 1 http://flybase.org/reports/FBgn0016659 - gene - - - H1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031384 CG4238 - http://flybase.org/reports/FBgn0031384 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:20363 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:20363 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:20363 CG4238 "IPR000569:HECT domain, IPR014756:Immunoglobulin E-set, IPR017868:Filamin/ABP280 repeat-like, IPR013783:Immunoglobulin-like fold" CG4238 11-Aug-17 DroID_v2017_08 "Drer\huwe1, Drer\arel1, Drer\hace1" "Scer\TOM1, Scer\RSP5" - "Xtro\hace1, Xtro\arel1, Xtro\hectd3" "Mmus\Hace1, Mmus\Hectd3, Mmus\Huwe1, Mmus\Arel1" "Hsap\HECTD3, Hsap\HUWE1, Hsap\AREL1, Hsap\HACE1" viable FBgn0266588 CR45113 - http://flybase.org/reports/FBgn0266588 non_protein_coding_gene - - - CR45113 - CR45113 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038704 CG5316 - http://flybase.org/reports/FBgn0038704 protein_coding_gene DNA 5'-adenosine monophosphate hydrolase activity ; GO:0033699 | inferred from electronic annotation with InterPro:IPR026963 damaged DNA binding ; GO:0003684 | inferred from sequence or structural similarity with UniProtKB:Q7Z2E3 "single strand break repair ; GO:0000012 | inferred from sequence or structural similarity with UniProtKB:Q7Z2E3-1 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay CG5316 "IPR011146:HIT-like domain, IPR019808:Histidine triad, conserved site, IPR013087:Zinc finger C2H2-type, IPR026963:Aprataxin, IPR032566:Aprataxin, C2HE/C2H2/C2HC zinc finger" CG5316 11-Aug-17 DroID_v2017_08 Drer\aptx Scer\HNT3 Cele\hint-3 Xtro\aptx Mmus\Aptx Hsap\APTX "viable,fertile" FBgn0051828 CG31828 - http://flybase.org/reports/FBgn0051828 protein_coding_gene - - - CG31828 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0083150 S(smoDN)2472 Suppressor of smoDN 2472 http://flybase.org/reports/FBgn0083150 gene - - - S(smoDN)2472 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013557 l(3)ry160 lethal (3) ry160 http://flybase.org/reports/FBgn0013557 - gene - - - "l(3)160, l(3)ry160" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003968 vao varied outspread http://flybase.org/reports/FBgn0003968 - gene - - - vao - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,viable,poor,visible,male,eye color defective,body color defective,lethal" "pigment cell,wing" FBgn0266583 Nrt::spi - http://flybase.org/reports/FBgn0266583 engineered_fusion_gene - - - "Nrt::spi, Nrt-Spi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "photoreceptor,ectopic,somatic clone,eye disc" FBgn0265060 CR44171 - http://flybase.org/reports/FBgn0265060 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44171, CR44171" - CR44171 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027238 l(1)G0277 lethal (1) G0277 http://flybase.org/reports/FBgn0027238 - gene - - - l(1)G0277 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0038008 CG3942 - http://flybase.org/reports/FBgn0038008 protein_coding_gene starch binding ; GO:2001070 | inferred from electronic annotation with InterPro:IPR002044 glycerophosphocholine phosphodiesterase activity ; GO:0047389 | inferred from biological aspect of ancestor with PANTHER:PTN001120996 glycerophosphodiester phosphodiesterase activity ; GO:0008889 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 glycerophospholipid catabolic process ; GO:0046475 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 cellular phosphate ion homeostasis ; GO:0030643 | inferred from biological aspect of ancestor with PANTHER:PTN000539050 - CG3942 "IPR030395:Glycerophosphodiester phosphodiesterase domain, IPR000909:Phosphatidylinositol-specific phospholipase C, X domain, IPR002044:Carbohydrate binding module family 20, IPR013784:Carbohydrate-binding-like fold, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR033506:Glycerophosphodiester phosphodiesterase Gde1, IPR013783:Immunoglobulin-like fold" CG3942 11-Aug-17 DroID_v2017_08 Drer\gpcpd1 "Scer\GDE1, Scer\PHO81" "Cele\gpcp-1, Cele\gpcp-2" Xtro\gpcpd1 Mmus\Gpcpd1 Hsap\GPCPD1 viable FBgn0065048 snoRNA:U3:54Aa snoRNA:U3:54Aa http://flybase.org/reports/FBgn0065048 snoRNA_gene - - - "snoRNA U3, snoRNA:U3:54Aa, CR33921, Dm-818, DmU3a(U3), U3 snoRNA, U3-snoRNA, 54A U3 snoRNA" - CR33921 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010947 l(3)10585 lethal (3) 10585 http://flybase.org/reports/FBgn0010947 - gene - - - l(3)10585 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0066322 zlo zloday http://flybase.org/reports/FBgn0066322 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available zlo - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0000044 Act57B Actin 57B http://flybase.org/reports/FBgn0000044 "FBgn0019861, FBgn0050294, FBgn0065030" protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity "positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype neuromuscular junction development, skeletal muscle fiber ; GO:0098529 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype heart development ; GO:0007507 | non-traceable author statement" plasma membrane ; GO:0005886 | inferred from direct assay actin filament ; GO:0005884 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay "Actin, actin, CG10067, T10, C, CG30294, act 57A, M, act57A, Act57A, BEST:RE38067, anon-EST:CL2c12, Act57B, Act57b, Act57, act57B, act57b, Actin 57B, chr2R:16452771..16452966, ArpE" "IPR020902:Actin/actin-like conserved site, IPR004000:Actin family, IPR004001:Actin, conserved site" CG10067 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-241j12.3, Drer\ankrd52b, Drer\acta1b, Drer\si:ch73-187m15.4, Drer\actc1b, Drer\zgc:86709, Drer\zgc:86725, Drer\actr1, Drer\actb1, Drer\actb2, Drer\actr10, Drer\acta1a, Drer\actc1a, Drer\acta2" "Scer\ACT1, Scer\ARP9, Scer\ARP4, Scer\ARP1" "Cele\act-4, Cele\arp-1, Cele\act-5, Cele\act-1, Cele\act-2, Cele\act-3" "Xtro\act3, Xtro\actc1, Xtro\actb, Xtro\acta2, Xtro\actr10, Xtro\actr1a, Xtro\actg1, Xtro\ankrd52, Xtro\acta1" "Mmus\Actl7b, Mmus\Acta2, Mmus\Actg1, Mmus\Actr10, Mmus\Actrt2, Mmus\Actbl2, Mmus\Actr1a, Mmus\Actrt3, Mmus\Actc1, Mmus\Actl9, Mmus\Actl10, Mmus\Actg2, Mmus\Actl11, Mmus\Actl7a, Mmus\Actr1b, Mmus\Acta1, Mmus\Actrt1, Mmus\Actb" "Hsap\POTEH, Hsap\ACTG1, Hsap\ACTA1, Hsap\ACTL7B, Hsap\ACTL9, Hsap\POTEJ, Hsap\ACTBL2, Hsap\ACTRT1, Hsap\ACTC1, Hsap\ACTR1A, Hsap\POTEB2, Hsap\POTEE, Hsap\ACTA2, Hsap\ACTL7A, Hsap\POTEB, Hsap\POTEG, Hsap\POTEI, Hsap\ACTR10, Hsap\POTEC, Hsap\ACTL8, Hsap\ACTL10, Hsap\POTED, Hsap\ACTRT2, Hsap\POTEA, Hsap\ACTRT3, Hsap\POTEF, Hsap\ACTB, Hsap\ACTR1B, Hsap\ACTG2" " larval stage , embryonic stage | late , embryonic stage " " embryonic/larval somatic muscle

, mesoderm

, larval muscle system

, pharyngeal muscle

" "lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage" germline cyst DRSC04042 I -0.96138894 -1.990773338 0.092595138 -1.057395086 -0.488582698 1.177050775 FBgn0010173 RpA-70 Replication Protein A 70 http://flybase.org/reports/FBgn0010173 - protein_coding_gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR004591 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR004591 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from sequence or structural similarity with UniProtKB:P27694 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs DNA-dependent DNA replication ; GO:0006261 | inferred from direct assay DNA replication factor A complex ; GO:0005662 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "DmRPA, D-RPA70, i164, CG9633, RPA, RPA 70, Rpa-70, dmrpa1, RP-A, RPA70, dRP-A, DRP-A, D-SSB, Ssb-70, RpA-70, RpA70, RPA1, RPA 70 kDa, RpA1" "IPR004365:OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR004591:Replication factor A protein 1, IPR007199:Replication factor-A protein 1, N-terminal, IPR012340:Nucleic acid-binding, OB-fold, IPR013955:Replication factor A, C-terminal, IPR031657:Replication protein A, OB domain" CG9633 11-Aug-17 DroID_v2017_08 Drer\rpa1 Scer\RFA1 "Cele\R03H10.6, Cele\sdz-24, Cele\R03H10.7, Cele\rpa-1" Xtro\rpa1 Mmus\Rpa1 Hsap\RPA1 embryonic stage "viable,fertile,lethal,partially lethal - majority die,visible,neuroanatomy defective" "mesothoracic tergum,lamina anlage,medulla anlage,larval optic anlage,larval outer optic anlage,somatic clone" FBgn0020417 I-element\gag I element gag http://flybase.org/reports/FBgn0020417 - transposable_element_gene - - - "ORF1, IF ORF1, I-element\gag, ORF1p, I-element ORF1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084041 CG41481 - http://flybase.org/reports/FBgn0084041 protein_coding_gene - - - CG41481 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011115 l(1)Q76 lethal (1) Q76 http://flybase.org/reports/FBgn0011115 FBgn0010210 gene - - - l(1)Q76 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001099 gdl gonadal http://flybase.org/reports/FBgn0001099 "FBgn0053088, FBgn0053756" protein_coding_gene - - - "CG7268, CG33088, CG33756, gdl" IPR010849:Gonadal family CG33756 11-Aug-17 DroID_v2017_08 Drer\dgcr6 - - Xtro\dgcr6 Mmus\Dgcr6 "Hsap\LOC102724770, Hsap\DGCR6, Hsap\DGCR6L" " adult stage | male , adult stage | female " " oocyte

, nurse cell

, testis

" FBgn0053784 CG33784 - http://flybase.org/reports/FBgn0053784 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "HDC12790, CG33784" IPR010512:Protein of unknown function DUF1091 CG33784 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019666 p56 p56 http://flybase.org/reports/FBgn0019666 - gene - - - p56 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052713 CG32713 - http://flybase.org/reports/FBgn0052713 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32713 "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG32713 11-Aug-17 DroID_v2017_08 Drer\ubb - - - Mmus\Rps27a Hsap\UBB FBgn0052412 QC Glutaminyl cyclase http://flybase.org/reports/FBgn0052412 protein_coding_gene glutaminyl-peptide cyclotransferase activity ; GO:0016603 | inferred from direct assay "peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase ; GO:0017186 | inferred from direct assay" extracellular region ; GO:0005576 | inferred from direct assay "CG10487, DromeQC, QC, CG32412" IPR007484:Peptidase M28 CG32412 11-Aug-17 DroID_v2017_08 "Drer\qpctlb, Drer\qpct, Drer\qpctla" Scer\YFR018C Cele\H27A22.1 "Xtro\qpct, Xtro\qpctl" "Mmus\Qpctl, Mmus\Qpct" "Hsap\QPCT, Hsap\QPCTL" "viable,visible" "chaeta,supernumerary" FBgn0015255 M(2)201 M(2)201 http://flybase.org/reports/FBgn0015255 - gene - - - M(2)201 - - 11-Aug-17 DroID_v2017_08 - - - - - - macrochaeta FBgn0039013 CG4813 - http://flybase.org/reports/FBgn0039013 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1913993 positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from electronic annotation with InterPro:IPR031824 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:1913993 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:1913993 CG4813 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR031824:E3 ubiquitin-protein ligase RNF220, middle domain" CG4813 11-Aug-17 DroID_v2017_08 "Drer\rnf220a, Drer\rnf220b" - Cele\ZK402.5 Xtro\rnf220.1 Mmus\Rnf220 Hsap\RNF220 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0001756 l(1)M4 lethal (1) M4 http://flybase.org/reports/FBgn0001756 - gene - - - l(1)M4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005195 l(2)Sp9b lethal (2) Sp9b http://flybase.org/reports/FBgn0005195 - gene - - - l(2)Sp9b - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0084369 E-2fb Enhancer on chromosome 2-complementation group fb http://flybase.org/reports/FBgn0084369 gene - - - "E-2f, E-2fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084423 l(3)S024833 l(3)S024833 http://flybase.org/reports/FBgn0084423 gene - - - l(3)S024833 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005495 l(1)tsG1 lethal (1) tsG1 http://flybase.org/reports/FBgn0005495 - gene - - - l(1)tsG1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cold sensitive" FBgn0025781 Cdc16 Cell division cycle 16 http://flybase.org/reports/FBgn0025781 - protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from mutant phenotype regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from mutant phenotype positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype - "Dmcdc16, CG6759, Cdc16, CDC16, cdc16, APC6, Apc6" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG6759 11-Aug-17 DroID_v2017_08 Drer\cdc16 Scer\CDC16 Cele\emb-27 Xtro\cdc16 Mmus\Cdc16 Hsap\CDC16 "increased cell death,mitotic cell cycle defective,lethal,neuroanatomy defective,viable,visible,melanotic mass phenotype" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,melanotic mass | third instar larval stage" FBgn0060632 l(3)S085208 lethal (3) S085208 http://flybase.org/reports/FBgn0060632 gene - - - "0852/08, l(3)S085208" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000850 fs(1)M39 female sterile (1) M39 http://flybase.org/reports/FBgn0000850 - gene - - - fs(1)M39 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0002605 M(2)56F Minute (2) 56F http://flybase.org/reports/FBgn0002605 - gene - - - "M(2)173, l(2)56Fc, M(2)56F, RpS18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive,viable,Minute" macrochaeta FBgn0001011 fs(3)A2 female sterile (3) A2 http://flybase.org/reports/FBgn0001011 - gene - - - fs(3)A2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0065605 l(2)SH0850 lethal (2) SH0850 http://flybase.org/reports/FBgn0065605 gene - - - "l(2)SH0850, l(2)SH2 0850" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004055 uzip unzipped http://flybase.org/reports/FBgn0004055 - protein_coding_gene - axonal fasciculation ; GO:0007413 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with Wnt5 inferred from genetic interaction with CadN sleep ; GO:0030431 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from direct assay "zip, nzip, CG3533, uzip" - CG3533 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260356 GSd236 - http://flybase.org/reports/FBgn0260356 gene - - - GSd236 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "ventral nerve cord,longitudinal connective" FBgn0028517 CG18478 - http://flybase.org/reports/FBgn0028517 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SPH157, DS07108.5, BG:DS07108.5, CG18478" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG18478 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Klk1b3, Mmus\Klk1b21, Mmus\Klk11, Mmus\Klk1b27, Mmus\Klk1b22, Mmus\Klk1b24, Mmus\Klk1b16, Mmus\Klk1b9, Mmus\Klk1, Mmus\F11, Mmus\Klkb1, Mmus\Klk1b11, Mmus\Klk1b5, Mmus\Egfbp2, Mmus\Klk1b1, Mmus\Klk1b4, Mmus\Klk1b8, Mmus\Klk1b26" "Hsap\KLK3, Hsap\KLKB1, Hsap\KLK1, Hsap\KLK2, Hsap\F11, Hsap\KLK11" FBgn0259950 CG42460 - http://flybase.org/reports/FBgn0259950 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG42460, DoxA3, PPO3" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42460 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043784 Bari1\ORF Bari1 element ORF http://flybase.org/reports/FBgn0043784 transposable_element_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002492, InterPro:IPR009057" "transposition, DNA-mediated ; GO:0006313 | inferred from electronic annotation with InterPro:IPR002492 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR002492" - "Bari-1, Bari1\ORF" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR002492:Transposase, Tc1-like, IPR009057:Homeobox domain-like" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000603 E(var)302 Enhancer of variegation 302 http://flybase.org/reports/FBgn0000603 - gene - - - "En(var)302, E(var)302" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,enhancer of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0261636 CR42719 - http://flybase.org/reports/FBgn0261636 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD03580, CG32345, CG42719, CR42719" - CR42719 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052243 CG32243 - http://flybase.org/reports/FBgn0052243 protein_coding_gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from biological aspect of ancestor with PANTHER:PTN000473820 cellular_component ; GO:0005575 | no biological data available "BcDNA:RE12890, CG32243" IPR031962:Domain of unknown function DUF4781 CG32243 11-Aug-17 DroID_v2017_08 - - Cele\F02C12.1 - - - viable DRSC08105 I 1.587919693 0.34373819 -0.155439225 0.627376982 0.133158093 1.436929838 FBgn0030465 CG15743 - http://flybase.org/reports/FBgn0030465 protein_coding_gene "inositol-1,4-bisphosphate 1-phosphatase activity ; GO:0004441 | inferred from sequence or structural similarity with RGD:621833 inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from sequence or structural similarity with UniProtKB:P29218" "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550 signal transduction ; GO:0007165 | inferred from sequence or structural similarity with UniProtKB:P29218 phosphate-containing compound metabolic process ; GO:0006796 | inferred from sequence or structural similarity with UniProtKB:P29218 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with RGD:621833 phosphatidylinositol biosynthetic process ; GO:0006661 | inferred from sequence or structural similarity with UniProtKB:P29218" endomembrane system ; GO:0012505 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P29218 CG15743 "IPR000760:Inositol monophosphatase-like, IPR020550:Inositol monophosphatase, conserved site" CG15743 11-Aug-17 DroID_v2017_08 Drer\impad1 "Scer\MET22, Scer\INM1" Cele\gpap-1 Xtro\impad1 Mmus\Impad1 Hsap\IMPAD1 "viable,fertile" FBgn0259381 C500 - http://flybase.org/reports/FBgn0259381 gene - - - C500 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0037197 CG13239 - http://flybase.org/reports/FBgn0037197 protein_coding_gene - - - CG13239 IPR032011:Domain of unknown function DUF4794 CG13239 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033862 CG6209 - http://flybase.org/reports/FBgn0033862 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG6209, mst101(2)" - CG6209 11-Aug-17 DroID_v2017_08 - - Cele\ZK546.14 - - Hsap\CYLC1 viable DRSC06968 K 0.256120799 0.14358835 0.090447844 -0.047401748 2.115177604 0.965855701 FBgn0038073 CG14395 - http://flybase.org/reports/FBgn0038073 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14395 IPR011993:PH domain-like CG14395 11-Aug-17 DroID_v2017_08 - - Cele\R148.5 - - - viable FBgn0083266 E(smoDN)461 Enhancer of smoDN 461 http://flybase.org/reports/FBgn0083266 gene - - - E(smoDN)461 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086300 lent lengthy http://flybase.org/reports/FBgn0086300 gene - filopodium assembly ; GO:0046847 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - lent - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal,recessive" "dendrite | larval stage,dendrite & filopodium & larva,dorsal multidendritic neuron ddaA & filopodium" FBgn0019693 l(3)68Fh lethal (3) 68Fh http://flybase.org/reports/FBgn0019693 - gene - - - "l(3)68Fc, l(3)68Fh" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267238 CR45678 - http://flybase.org/reports/FBgn0267238 non_protein_coding_gene - - - "CR45678, lincRNA.628" - CR45678 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060329 l(3)S146315 lethal (3) S146315 http://flybase.org/reports/FBgn0060329 gene - - - "1463/15, l(3)S146315" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0051382 tRNA:Asp-GTC-1-12 transfer RNA:Aspartic acid-GTC 1-12 http://flybase.org/reports/FBgn0051382 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "AE002708.trna31-AspGTC, tRNA:D:GTC:AE002708-b, CR31382, tRNA[[Asp]], tRNA[Asp-GTC], chr3R.trna37-AspGTC, tRNA:Asp-GTC-1-12, tRNA:CR31382, tRNA-Asp-GTC-1-12, GAC" - CR31382 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011288 Snap25 Synaptosomal-associated protein 25kDa http://flybase.org/reports/FBgn0011288 "FBan0040452, FBgn0039960, FBgn0039996" protein_coding_gene "syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000447753 protein binding ; GO:0005515 | inferred from physical interaction with Syt1, Syt4 SNARE binding ; GO:0000149 | inferred from physical interaction with nSyb, Syx1A SNAP receptor activity ; GO:0005484 | inferred from direct assay SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNAP receptor activity ; GO:0005484 | non-traceable author statement" regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from direct assay neuromuscular synaptic transmission ; GO:0007274 | inferred from expression pattern synaptic vesicle priming ; GO:0016082 | inferred from direct assay vesicle fusion ; GO:0006906 | inferred from direct assay Golgi to plasma membrane transport ; GO:0006893 | inferred from sequence or structural similarity vesicle-mediated transport ; GO:0016192 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle fusion to presynaptic active zone membrane ; GO:0031629 | inferred from direct assay synaptic vesicle transport ; GO:0048489 | inferred from direct assay synaptic vesicle docking ; GO:0016081 | non-traceable author statement membrane ; GO:0016020 | inferred from sequence or structural similarity with UniProtKB:P60879 plasma membrane ; GO:0005886 | inferred from direct assay BLOC-1 complex ; GO:0031083 | colocalizes_with inferred from sequence or structural similarity with UniProtKB:P60880 inferred from sequence or structural similarity with UniProtKB:Q17QQ3 terminal bouton ; GO:0043195 | inferred from direct assay plasma membrane ; GO:0005886 | non-traceable author statement SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with UniProtKB:P60880-1 SNARE complex ; GO:0031201 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P60879 synapse ; GO:0045202 | "SNAP-25, snap-25, SNAP25, snp25, CG17884, CG17676, CG40452, Snap25, snap25, dSNAP-25" "IPR000727:Target SNARE coiled-coil homology domain, IPR000928:SNAP-25" CG40452 11-Aug-17 DroID_v2017_08 "Drer\snap25b, Drer\zgc:101731, Drer\snap29, Drer\snap23.1, Drer\snap23.2, Drer\snap25a" "Scer\SEC9, Scer\SPO20" "Cele\ric-4, Cele\aex-4" "Xtro\snap23, Xtro\snap47, Xtro\snap25, Xtro\LOC100491227, Xtro\snap29" "Mmus\Snap29, Mmus\Snap25, Mmus\Snap47, Mmus\Snap23" "Hsap\SNAP25, Hsap\SNAP29, Hsap\SNAP23, Hsap\SNAP47" " adult stage , larval stage , embryonic stage | stage>=14 " " optic lobe

, abdominal neuromere

, subesophageal ganglion

, thoracico-abdominal ganglion

, ventral nerve cord

, neuron

, adult brain

" " embryonic stage | stage >=14 , embryonic stage | stage 16 " " ventral nerve cord

, chordotonal organ

" "paralytic,heat sensitive,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal,viable,neurophysiology defective,temperature conditional,neuroanatomy defective" "neuromuscular junction,neuromuscular junction | temperature conditional1-16),t-bar" FBgn0044033 Mod(rst)K35 Mod(rst)K35 http://flybase.org/reports/FBgn0044033 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "K35, Mod(rst)K35" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0005081 fs(2)OW805 female sterile (2) OW805 http://flybase.org/reports/FBgn0005081 - gene - - - fs(2)OW805 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038924 CG6028 - http://flybase.org/reports/FBgn0038924 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011234 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR011234 - CG6028 "IPR011234:Fumarylacetoacetase, C-terminal-related" CG6028 11-Aug-17 DroID_v2017_08 "Drer\fahd2a, Drer\fahd1" Scer\FMP41 Cele\fahd-1 Xtro\fahd2a "Mmus\Fahd2a, Mmus\Fahd1" "Hsap\FAHD2A, Hsap\FAHD2B, Hsap\FAHD1" FBgn0069223 gl(2R)2-11 gl(2R)2-11 http://flybase.org/reports/FBgn0069223 gene molecular_function ; GO:0003674 | no biological data available anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2R)2-11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic abdominal segment,germline clone,maternal effect,embryo,posterior" FBgn0267771 CR46102 - http://flybase.org/reports/FBgn0267771 non_protein_coding_gene - - - CR46102 - CR46102 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065933 l(2)SH0130 lethal (2) SH0130 http://flybase.org/reports/FBgn0065933 gene - - - "l(2)SH0130, l(2)SH2 0130" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260866 dnr1 defense repressor 1 http://flybase.org/reports/FBgn0260866 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:21155 ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN001150528 zinc ion binding ; GO:0008270 | inferred from sequence model negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0002814 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN001150528 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:21155 cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 cellular_component ; GO:0005575 | no biological data available "Dnr1, CG12489, dnr1, defense repressor 1, DNR1" "IPR000299:FERM domain, IPR001841:Zinc finger, RING-type, IPR011993:PH domain-like, IPR018979:FERM, N-terminal, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR018980:FERM, C-terminal PH-like domain" CG12489 11-Aug-17 DroID_v2017_08 "Drer\mylipa, Drer\mylipb" - - Xtro\mylip Mmus\Mylip Hsap\MYLIP FBgn0035592 CG10674 - http://flybase.org/reports/FBgn0035592 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10674 IPR005351:Uncharacterised protein family UPF0139 CG10674 11-Aug-17 DroID_v2017_08 Drer\zgc:73111 - Cele\K10B2.4 Xtro\wdr83os Mmus\Wdr83os Hsap\WDR83OS "viable,fertile" FBgn0052536 CG32536 - http://flybase.org/reports/FBgn0052536 protein_coding_gene - - - "CG8020, CG32536" IPR017025:Cancer-associated antigen RCAS1 CG32536 11-Aug-17 DroID_v2017_08 Drer\ebag9 - Cele\ZK154.4 Xtro\ebag9 Mmus\Ebag9 Hsap\EBAG9 DRSC20074 E 0.021298851 -0.090543383 1.510196946 0.503022244 0.024750045 -0.043207404 FBgn0034069 CG8401 - http://flybase.org/reports/FBgn0034069 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8401 IPR031751:Protein of unknown function DUF4735 CG8401 11-Aug-17 DroID_v2017_08 Drer\si:ch211-76l23.7 - - - Mmus\AU021092 Hsap\C16orf89 viable FBgn0267732 CR46063 - http://flybase.org/reports/FBgn0267732 non_protein_coding_gene - - - CR46063 - CR46063 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259398 C909 - http://flybase.org/reports/FBgn0259398 gene - - - C909 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0267427 CR45780 - http://flybase.org/reports/FBgn0267427 pseudogene_attribute - - - "CR45780, Mst77Y" - CR45780 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027582 CG6230 - http://flybase.org/reports/FBgn0027582 - protein_coding_gene "nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR008250, InterPro:IPR023299 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250 calcium-transporting ATPase activity ; GO:0005388 | inferred from biological aspect of ancestor with PANTHER:PTN000643812" cation transport ; GO:0006812 | inferred from electronic annotation with InterPro:IPR006544 cellular calcium ion homeostasis ; GO:0006874 | inferred from biological aspect of ancestor with PANTHER:PTN000643319 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000642960 endomembrane system ; GO:0012505 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000642960 "dCOD1, BcDNA:GH06032, CG6230" "IPR001757:P-type ATPase, IPR006544:P-type ATPase, subfamily V, IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site, IPR023298:P-type ATPase, transmembrane domain, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N" CG6230 11-Aug-17 DroID_v2017_08 Drer\atp13a1 Scer\SPF1 "Cele\catp-5, Cele\catp-8" Xtro\atp13a1 Mmus\Atp13a1 Hsap\ATP13A1 "viable,visible" trichogen cell FBgn0036210 CG14130 - http://flybase.org/reports/FBgn0036210 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of mitochondrial membrane permeability involved in programmed necrotic cell death ; GO:1902445 | inferred from electronic annotation with InterPro:IPR032870 cellular response to DNA damage stimulus ; GO:0006974 | inferred from electronic annotation with InterPro:IPR032870 fatty acid metabolic process ; GO:0006631 | inferred from sequence or structural similarity with MGI:MGI:1913650 mitochondrial matrix ; GO:0005759 | inferred from electronic annotation with InterPro:IPR032870 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:1913650 CG14130 "IPR027450:Alpha-ketoglutarate-dependent dioxygenase AlkB-like, IPR032870:Alpha-ketoglutarate-dependent dioxygenase alkB homologue 7" CG14130 11-Aug-17 DroID_v2017_08 "Drer\alkbh8, Drer\alkbh7" - Cele\Y46G5A.35 "Xtro\alkbh7, Xtro\alkbh8" "Mmus\Alkbh8, Mmus\Alkbh7" "Hsap\ALKBH7, Hsap\ALKBH8" viable FBgn0038519 Prx3 Peroxiredoxin 3 http://flybase.org/reports/FBgn0038519 protein_coding_gene antioxidant activity ; GO:0016209 | inferred from sequence or structural similarity with UniProtKB:P30048 thioredoxin peroxidase activity ; GO:0008379 | inferred from direct assay "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 phagocytosis ; GO:0006909 | inferred from mutant phenotype cell redox homeostasis ; GO:0045454 | inferred from genetic interaction with Prx5 determination of adult lifespan ; GO:0008340 | inferred from genetic interaction with Prx5 hydrogen peroxide catabolic process ; GO:0042744 | inferred from direct assay cell redox homeostasis ; GO:0045454 | inferred from sequence or structural similarity with UniProtKB:P30048 negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype inferred from genetic interaction with Prx5" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P30048 "DPx-5037, CG5826, DPx5037, Prx5037, peroxiredoxin 5037, mTPx, mtTPx, Prx3, dPrx3" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR013766:Thioredoxin domain" CG5826 11-Aug-17 DroID_v2017_08 "Drer\prdx6, Drer\prdx2, Drer\prdx3, Drer\prdx4, Drer\prdx1" "Scer\TSA2, Scer\TSA1, Scer\DOT5, Scer\PRX1" "Cele\prdx-2, Cele\prdx-3, Cele\prdx-6" "Xtro\prdx2, Xtro\prdx4, Xtro\prdx1, Xtro\prdx3" "Mmus\Prdx4, Mmus\Prdx3, Mmus\Prdx1, Mmus\Prdx6, Mmus\Prdx2" "Hsap\PRDX1, Hsap\PRDX3, Hsap\PRDX6, Hsap\PRDX4, Hsap\PRDX2" "stress response defective,increased cell death,viable" FBgn0039194 CG13614 - http://flybase.org/reports/FBgn0039194 protein_coding_gene - - - CG13614 IPR006631:Protein of unknown function DM4/12 CG13614 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004705 l(2)56Fg lethal (2) 56Fg http://flybase.org/reports/FBgn0004705 - gene - - - "l(2)56F, l(2)56Fg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0086420 l(3)CHd lethal (3) CHd http://flybase.org/reports/FBgn0086420 gene - - - l(3)CHd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003242 Roof Roof http://flybase.org/reports/FBgn0003242 - gene - - - "Roof, Rf" - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0267754 CR46085 - http://flybase.org/reports/FBgn0267754 non_protein_coding_gene - - - CR46085 - CR46085 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061038 l(3)S023837b lethal (3) S023837b http://flybase.org/reports/FBgn0061038 gene - - - "0238/37, l(3)S023837b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0264662 spikes spikes http://flybase.org/reports/FBgn0264662 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - spikes - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0034398 CG15098 - http://flybase.org/reports/FBgn0034398 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from sequence model "CG15098, dmCG15098" IPR031720:Protein of unknown function DUF4728 CG15098 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC06527 E -0.806457665 -1.413043159 -0.209431783 -1.526684042 -0.834180608 0.54635129 FBgn0026076 UBL3 UBL3 http://flybase.org/reports/FBgn0026076 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Ubl3, HCG-1, CG9038, UBL3, MUB" "IPR000626:Ubiquitin domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029071:Ubiquitin-related domain" CG9038 11-Aug-17 DroID_v2017_08 "Drer\skor1b, Drer\ubl3a, Drer\ubl3b, Drer\skor1a" - Cele\C46F11.6 "Xtro\ubl3, Xtro\skor1" "Mmus\Ubl3, Mmus\Skor2" "Hsap\UBL3, Hsap\SKOR2, Hsap\SKOR1" lethal FBgn0021825 DCTN2-p50 "Dynactin 2, p50 subunit" http://flybase.org/reports/FBgn0021825 FBgn0033338 protein_coding_gene - microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with UniProtKB:Q13561 phototransduction ; GO:0007602 | inferred from mutant phenotype mRNA transport ; GO:0051028 | inferred from direct assay positive regulation of retrograde axon cargo transport ; GO:2001019 | inferred from mutant phenotype retrograde axonal transport ; GO:0008090 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from sequence or structural similarity with UniProtKB:Q13561 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from biological aspect of ancestor with PANTHER:PTN000394123 photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype centrosome localization ; GO:0051642 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from mutant phenotype mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with UniProtKB:Q13561 dynactin complex ; GO:0005869 | inferred from sequence or structural similarity centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN001034318 dynactin complex ; GO:0005869 | inferred from biological aspect of ancestor with PANTHER:PTN000394123 dynactin complex ; GO:0005869 | inferred from sequence or structural similarity with UniProtKB:Q13561 "P50, p50/dynamitin, p50/Dmn, dmn, CG8269, l(2)k16218, l(2)k16109, Dynamitin, dDyn, Dmn, p50, dyna, DMN, p50[Dmn], DCTN2, DCTN2-p50" IPR028133:Dynamitin CG8269 11-Aug-17 DroID_v2017_08 Drer\dctn2 Scer\JNM1 Cele\dnc-2 Xtro\dctn2 Mmus\Dctn2 Hsap\DCTN2 "lethal,recessive,viable,fertile,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "oocyte,germline clone,stage S9 oocyte & nucleus,dorsal appendage,embryonic/larval nervous system,oocyte & nucleusmat.‘±Tub67C.THsimVP16,embryonic/larval neuroblast,ganglion mother cell" FBgn0013622 l(3)neo12 lethal (3) neo12 http://flybase.org/reports/FBgn0013622 - gene - - - l(3)neo12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034750 CG3732 - http://flybase.org/reports/FBgn0034750 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 - - CG3732 "IPR001876:Zinc finger, RanBP2-type, IPR017337:Uncharacterised conserved protein UCP037956, zinc finger Ran-binding" CG3732 11-Aug-17 DroID_v2017_08 "Drer\ewsr1b, Drer\zranb2, Drer\ewsr1a, Drer\taf15" - Cele\Y25C1A.8 "Xtro\zranb2, Xtro\ewsr1" "Mmus\Zranb2, Mmus\Ewsr1" "Hsap\ZRANB2, Hsap\EWSR1" FBgn0264982 CR44133 - http://flybase.org/reports/FBgn0264982 non_protein_coding_gene - - - CR44133 - CR44133 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065344 l(2)SH1821 lethal (2) SH1821 http://flybase.org/reports/FBgn0065344 gene - - - "l(2)SH1821, l(2)SH2 1821" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000860 fs(1)M54 female sterile (1) M54 http://flybase.org/reports/FBgn0000860 - gene - - - fs(1)M54 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" FBgn0015231 God60D Godzilla at 60D http://flybase.org/reports/FBgn0015231 - gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available "God60D, God" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "wing vein,embryonic abdomen,maternal effect" FBgn0031775 CG9150 - http://flybase.org/reports/FBgn0031775 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - CG9150 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG9150 11-Aug-17 DroID_v2017_08 "Drer\rdh8a, Drer\dhrs11b, Drer\zgc:153724, Drer\zgc:92630, Drer\rdh8b, Drer\dhrs11a" Scer\YMR226C "Cele\H04M03.3, Cele\F28H7.2, Cele\R05D8.7" "Xtro\rdh7, Xtro\dhrs11, Xtro\rdh8" "Mmus\Rdh1, Mmus\Rdh8, Mmus\Dhrs11" "Hsap\RDH8, Hsap\DHRS11, Hsap\RDH16" viable FBgn0032345 CG14921 - http://flybase.org/reports/FBgn0032345 protein_coding_gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - CG14921 "IPR007052:CS domain, IPR008978:HSP20-like chaperone" CG14921 11-Aug-17 DroID_v2017_08 "Drer\ttc25, Drer\kdm6a, Drer\tmtc3, Drer\ifit15, Drer\ifit8, Drer\kdm6al, Drer\tomm34, Drer\bbs4, Drer\ifit9, Drer\spag1a, Drer\ifit16, Drer\spag1b, Drer\dyx1c1, Drer\fkbpl, Drer\ogt.1, Drer\kdm6ba, Drer\ifit14, Drer\ttc6, Drer\ogt.2" "Scer\SWA2, Scer\TAH1, Scer\CYC8" - "Xtro\kdm6b, Xtro\spag1, Xtro\dyx1c1, Xtro\kdm6a, Xtro\bbs4, Xtro\ogt, Xtro\ttc25, Xtro\tmtc3, Xtro\ttc16, Xtro\ifit5" "Mmus\Bbs4, Mmus\Spag1, Mmus\Tmtc1, Mmus\Kdm6b, Mmus\Ifit1bl1, Mmus\Ifit3b, Mmus\Fkbpl, Mmus\Uty, Mmus\Ifit3, Mmus\Ifit2, Mmus\Tmtc3, Mmus\Tomm34, Mmus\Ifit1bl2, Mmus\Lonrf3, Mmus\Kdm6a, Mmus\Ttc24, Mmus\Ttc16, Mmus\Ifit1, Mmus\Ttc25, Mmus\Ogt, Mmus\Dyx1c1" "Hsap\LONRF3, Hsap\TTC32, Hsap\IFIT3, Hsap\LONRF2, Hsap\IFIT1B, Hsap\FKBPL, Hsap\IFIT1, Hsap\SPAG1, Hsap\UTY, Hsap\DYX1C1, Hsap\IFIT2, Hsap\KDM6B, Hsap\TMTC1, Hsap\TTC24, Hsap\TOMM34, Hsap\BBS4, Hsap\TTC16, Hsap\TTC6, Hsap\TMTC3, Hsap\OGT, Hsap\KDM6A, Hsap\IFIT5" "viable,auditory perception defective,neurophysiology defective" FBgn0004697 wapm wings apart mimic http://flybase.org/reports/FBgn0004697 - gene - - - wapm - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile" wing FBgn0003666 taw tawny http://flybase.org/reports/FBgn0003666 - gene - - - taw - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile,body color defective" "adult head,adult thorax,adult abdomen,wing,tergite,female" FBgn0041709 yellow-g yellow-g http://flybase.org/reports/FBgn0041709 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG5717, yellow-g, yell-g, g" "IPR011044:Quinoprotein amine dehydrogenase, beta chain-like, IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG5717 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\fbxa-76, Cele\C24H12.1, Cele\F49E11.8, Cele\T27A1.3" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 "female sterile,male fertile,viable,visible" "chorion,stage S14 oocyte & vitelline membrane,trichogen cell" FBgn0031267 Ipk2 Ipk2 http://flybase.org/reports/FBgn0031267 protein_coding_gene "inositol-1,4,5-trisphosphate 3-kinase activity ; GO:0008440 | inferred from direct assay inositol-1,4,5-trisphosphate 6-kinase activity ; GO:0000823 | inferred from direct assay inositol tetrakisphosphate 5-kinase activity ; GO:0047326 | inferred from direct assay" inositol phosphate biosynthetic process ; GO:0032958 | inferred from direct assay positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay "CG13688, dmIpk2, Ipk2, ipk2" IPR005522:Inositol polyphosphate kinase CG13688 11-Aug-17 DroID_v2017_08 "Drer\ip6k1, Drer\ip6k2b, Drer\ip6k2a, Drer\ipmka, Drer\ipmkb" "Scer\ARG82, Scer\KCS1" "Cele\F30A10.3, Cele\ZK795.1, Cele\Y22D7AR.6" "Xtro\ip6k2, Xtro\ipmk" "Mmus\Ip6k2, Mmus\Ipmk, Mmus\Ip6k1, Mmus\Ip6k3" "Hsap\IP6K3, Hsap\IPMK, Hsap\IP6K1, Hsap\IP6K2" viable FBgn0039441 TwdlN TweedleN http://flybase.org/reports/FBgn0039441 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "BcDNA:RE59605, BcDNA:RE20092, TwdlN, CG5476, chr3R:22457526..22457631" IPR004145:Domain of unknown function DUF243 CG5476 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0026221 l(3)04704a lethal (3) 04704a http://flybase.org/reports/FBgn0026221 - gene - - - "l(3)04704, l(3)04704a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0261283 SREBP Sterol regulatory element binding protein http://flybase.org/reports/FBgn0261283 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" "phagocytosis ; GO:0006909 | inferred from mutant phenotype fatty acid biosynthetic process ; GO:0006633 | non-traceable author statement cell morphogenesis ; GO:0000902 | inferred from mutant phenotype regulation of mitophagy ; GO:1903146 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement regulation of fatty acid biosynthetic process ; GO:0042304 | traceable author statement fatty acid homeostasis ; GO:0055089 | inferred from mutant phenotype SREBP signaling pathway ; GO:0032933 | inferred from direct assay" nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay "HLH106, SREBP, dSREBP, dsrebp, CG8522, Srebp, HlH106, l(3)76BDw, dSrebp, srebp, SREBF1" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8522 11-Aug-17 DroID_v2017_08 "Drer\tfeb, Drer\mitfb, Drer\mitfa, Drer\usf1l, Drer\srebf2, Drer\srebf1, Drer\usf2, Drer\usf1" "Scer\RTG3, Scer\HMS1" "Cele\hlh-30, Cele\sbp-1" "Xtro\srebf1, Xtro\srebf2" "Mmus\Usf1, Mmus\Tfe3, Mmus\Srebf2, Mmus\Srebf1, Mmus\Mitf, Mmus\Tfeb" "Hsap\MITF, Hsap\SREBF1, Hsap\TFEB, Hsap\SREBF2, Hsap\USF2, Hsap\USF1" embryonic stage -- adult stage DRSC11182 EK -0.799301338 0.365729695 2.730670112 -1.900429543 -2.127117432 -1.669485193 FBgn0032668 CG17681 - http://flybase.org/reports/FBgn0032668 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 - - CG17681 "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG17681 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-106k19.2, Drer\si:dkey-76k16.5, Drer\si:dkey-76k16.6" - Cele\ZK185.3 - "Mmus\Glyat, Mmus\Glyatl3, Mmus\Gm4952, Mmus\Keg1" "Hsap\GLYATL3, Hsap\GLYATL2, Hsap\GLYAT, Hsap\GLYATL1" viable DRSC02632 K -0.181148511 -0.40662878 -0.950649978 0.058977011 -1.533088565 -0.629538505 FBgn0033879 CG6543 - http://flybase.org/reports/FBgn0033879 protein_coding_gene enoyl-CoA hydratase activity ; GO:0004300 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 enoyl-CoA hydratase activity ; GO:0004300 | inferred from sequence or structural similarity with UniProtKB:P30084 fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with UniProtKB:P30084 fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P30084 microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG18645, CG6543, Echs1" "IPR001753:Crotonase superfamily, IPR018376:Enoyl-CoA hydratase/isomerase, conserved site, IPR029045:ClpP/crotonase-like domain, IPR014748:Crontonase, C-terminal" CG6543 11-Aug-17 DroID_v2017_08 "Drer\echdc1, Drer\echs1" "Scer\ECI1, Scer\DCI1" "Cele\ech-6, Cele\ech-7, Cele\ech-3" "Xtro\echs1, Xtro\echdc1" "Mmus\Echdc1, Mmus\Echs1" "Hsap\ECHS1, Hsap\ECHDC1" "viable,fertile,immune response defective" FBgn0061048 l(3)S023447 lethal (3) S023447 http://flybase.org/reports/FBgn0061048 gene - - - "0234/47, l(3)S023447" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0003635 Su(var)330 Suppressor of variegation 330 http://flybase.org/reports/FBgn0003635 - gene - - - Su(var)330 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant" FBgn0264562 Hr4 Hormone receptor 4 http://flybase.org/reports/FBgn0264562 protein_coding_gene "steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | inferred from mutant phenotype RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000637657 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR013088 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype regulation of developmental growth ; GO:0048638 | inferred from mutant phenotype intracellular steroid hormone receptor signaling pathway ; GO:0030518 | inferred from mutant phenotype growth ; GO:0040007 | inferred from mutant phenotype" transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000637657 nucleus ; GO:0005634 | inferred from direct assay "DHR4, Hr4, null, CG43934, CG16902, CG3600, EG:BACH61I5.1, EP1232, EP(X)1232, NR6A2, EG:133E12.2, GRF, CG43692, CG42527, HR4" "IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR000536:Nuclear hormone receptor, ligand-binding domain" CG43934 11-Aug-17 DroID_v2017_08 "Drer\rxrba, Drer\nr3c1, Drer\raraa, Drer\ar, Drer\pparda, Drer\nr1h5, Drer\esrrd, Drer\vdrb, Drer\rxrga, Drer\nr6a1b, Drer\nr6a1a, Drer\nr2c2, Drer\esrra, Drer\nr2f5, Drer\ppardb, Drer\vdra, Drer\nr2f1a, Drer\pgr, Drer\esr1, Drer\pparaa, Drer\rxraa, Drer\nr2f6a, Drer\nr2e1, Drer\nr2f2, Drer\esrrga, Drer\nr1i2, Drer\rxrab, Drer\nr5a1a, Drer\esr2a, Drer\nr2f1b, Drer\nr2c1, Drer\rarab, Drer\thrab, Drer\nr1h4, Drer\nr2f6b, Drer\nr0b2a, Drer\nr2e3, Drer\rargb, Drer\nr0b1, Drer\nr0b2b, Drer\rxrbb, Drer\pparab, Drer\esr2b, Drer\pparg" - Cele\nhr-91 "Xtro\nr2f1, Xtro\ppara, Xtro\nr2e3, Xtro\esrrb, Xtro\nr0b1, Xtro\nr1h2, Xtro\nr2c2, Xtro\pgr, Xtro\nr2e1, Xtro\esr2, Xtro\esrrgr, Xtro\esrra, Xtro\rxrg, Xtro\thrb, Xtro\pparg, Xtro\ar, Xtro\esrrg, Xtro\rxra, Xtro\nr3c2, Xtro\nr2f2, Xtro\nr0b2, Xtro\nr2f5, Xtro\rxrb, Xtro\esr1, Xtro\rarg, Xtro\rarb, Xtro\vdr, Xtro\rara, Xtro\nr1h5, Xtro\nr2f6, Xtro\ppard, Xtro\nr1i2, Xtro\nr2c1, Xtro\nr6a1, Xtro\nr3c1" "Mmus\Nr2e3, Mmus\Ar, Mmus\Nr1h4, Mmus\Esrrb, Mmus\Nr1h3, Mmus\Esr2, Mmus\Esr1, Mmus\Esrra, Mmus\Nr1i3, Mmus\Nr1i2, Mmus\Esrrg, Mmus\Nr0b2, Mmus\Rxrb, Mmus\Nr2f6, Mmus\Nr2f2, Mmus\Rarg, Mmus\Nr6a1, Mmus\Pparg, Mmus\Nr2e1, Mmus\Pgr, Mmus\Ppard, Mmus\Rxra, Mmus\Nr1h2, Mmus\Vdr, Mmus\Nr1h5, Mmus\Nr2c1, Mmus\Thrb, Mmus\Ppara, Mmus\Nr3c1, Mmus\Nr2c2, Mmus\Thra, Mmus\Rara, Mmus\Rarb, Mmus\Nr3c2, Mmus\Rxrg, Mmus\Nr0b1, Mmus\Nr2f1" "Hsap\NR2E1, Hsap\ESRRB, Hsap\NR2F2, Hsap\PPARA, Hsap\NR0B1, Hsap\ESR2, Hsap\NR1H3, Hsap\ESRRA, Hsap\PPARD, Hsap\RXRB, Hsap\ESRRG, Hsap\NR2C2, Hsap\NR0B2, Hsap\NR2C1, Hsap\RXRG, Hsap\NR3C2, Hsap\AR, Hsap\PGR, Hsap\RARG, Hsap\NR1H4, Hsap\RXRA, Hsap\RARA, Hsap\RARB, Hsap\NR1H2, Hsap\NR1I3, Hsap\NR3C1, Hsap\VDR, Hsap\NR2F6, Hsap\NR6A1, Hsap\THRB, Hsap\THRA, Hsap\NR1I2, Hsap\PPARG, Hsap\ESR1, Hsap\NR2F1" DRSC18599 E -0.222993089 -1.247564109 -0.904588725 -3.012265174 0.202447379 0.984270182 FBgn0266512 s-484 - http://flybase.org/reports/FBgn0266512 gene - - - s-484 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262031 CR42842 - http://flybase.org/reports/FBgn0262031 pseudogene_attribute - - - CR42842 - CR42842 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086553 MRE22 mRNA-like ncRNA in embryogenesis 22 http://flybase.org/reports/FBgn0086553 non_protein_coding_gene - - - "MRE22, LD33458" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053217 CG33217 - http://flybase.org/reports/FBgn0053217 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE15216, CG33217" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG33217 11-Aug-17 DroID_v2017_08 Drer\pelp1 - - Xtro\pelp1 Mmus\Pelp1 Hsap\PELP1 FBgn0013496 l(1)14Ae lethal (1) 14Ae http://flybase.org/reports/FBgn0013496 - gene - - - "I, l(1)I, l(1)13Fh, l(1)14Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039419 CG12290 - http://flybase.org/reports/FBgn0039419 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "anon-WO0170980.50, anon-WO0170980.49, CG12290, lincRNA.S7704" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG12290 11-Aug-17 DroID_v2017_08 "Drer\hrh3, Drer\LOC100331077, Drer\hrh4, Drer\LOC101886918" - - - "Mmus\Hrh3, Mmus\Hrh4" "Hsap\HRH3, Hsap\HRH4" viable FBgn0082185 l(3)SzB93Ba lethal (3) SzB93Ba http://flybase.org/reports/FBgn0082185 gene - - - l(3)SzB93Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0260456 CG4806 - http://flybase.org/reports/FBgn0260456 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype - "cg4806, CG4806" IPR000504:RNA recognition motif domain CG4806 11-Aug-17 DroID_v2017_08 Drer\rbm28 Scer\NOP4 Cele\rbm-28 Xtro\rbm28 Mmus\Rbm28 Hsap\RBM28 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0037026 CG3634 - http://flybase.org/reports/FBgn0037026 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - CG3634 "IPR007311:ST7, IPR011990:Tetratricopeptide-like helical domain" CG3634 11-Aug-17 DroID_v2017_08 "Drer\st7l, Drer\st7" - Cele\F11A10.5 "Xtro\st7l, Xtro\st7" "Mmus\St7l, Mmus\St7" "Hsap\ST7L, Hsap\ST7" viable DRSC11747 K 0.946812598 0.626548924 -0.342703977 0.242481315 1.754114206 1.217061446 FBgn0086785 Vps36 Vacuolar protein sorting 36 http://flybase.org/reports/FBgn0086785 protein_coding_gene phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from electronic annotation with InterPro:IPR021648 ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000004409 ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000319648 mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from expression pattern bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from direct assay protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043328 | inferred from biological aspect of ancestor with PANTHER:PTN000319648 regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from sequence or structural similarity with UniProtKB:Q86VN1 late endosome membrane ; GO:0031902 | inferred from biological aspect of ancestor with PANTHER:PTN000319648 ESCRT II complex ; GO:0000814 | inferred from biological aspect of ancestor with PANTHER:PTN000319648 ESCRT II complex ; GO:0000814 | inferred from sequence or structural similarity with SGD:S000004409 cytoplasm ; GO:0005737 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "Vps36, CG10711, l(3)L5212, vps36" "IPR007286:EAP30, IPR011993:PH domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR021648:Vacuolar protein sorting protein 36, GLUE domain" CG10711 11-Aug-17 DroID_v2017_08 Drer\vps36 Scer\VPS36 Cele\vps-36 Xtro\vps36 Mmus\Vps36 Hsap\VPS36 DRSC09785 I 1.744984239 -0.254723909 0.871794262 0.345305041 0.324132878 0.13887001 FBgn0004223 l(3)84Fk lethal (3) 84Fk http://flybase.org/reports/FBgn0004223 - gene - - - l(3)84Fk - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032878 CG9316 - http://flybase.org/reports/FBgn0032878 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "38E.9, CG9316, FBXL10" "IPR032675:Leucine-rich repeat domain, L domain-like" CG9316 11-Aug-17 DroID_v2017_08 "Drer\kdm2aa, Drer\fbxl15, Drer\si:dkey-192l18.9, Drer\fbxl17, Drer\zgc:158376, Drer\fbxl4, Drer\fbxl6, Drer\kdm2ab, Drer\usp32" Scer\GRR1 "Cele\B0393.3, Cele\EEED8.10" "Xtro\kdm2b, Xtro\fbxl4, Xtro\fbxl19, Xtro\fbxl12" "Mmus\Fbxl4, Mmus\Fbxl17, Mmus\Fbxl6, Mmus\Kdm2b, Mmus\Lrrc29, Mmus\Usp32, Mmus\Fbxl12, Mmus\Fbxl19, Mmus\Fbxl21, Mmus\Kdm2a" "Hsap\FBXL17, Hsap\FBXL19, Hsap\FBXL12, Hsap\KDM2B, Hsap\FBXL6, Hsap\FBXL4, Hsap\LRRC29, Hsap\FBXL13, Hsap\USP32, Hsap\KDM2A" viable FBgn0005073 fs(2)OW214 female sterile (2) OW214 http://flybase.org/reports/FBgn0005073 - gene - - - fs(2)OW214 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082861 BP1045 BP1045 http://flybase.org/reports/FBgn0082861 gene - - - BP1045 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266219 CR44914 - http://flybase.org/reports/FBgn0266219 non_protein_coding_gene - - - "CR44914, R5_2L:6873342..6874179" - CR44914 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035858 CG13674 - http://flybase.org/reports/FBgn0035858 protein_coding_gene - - - CG13674 - CG13674 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell DRSC10033 IE -1.903780055 0.736353061 2.187046671 0.734606717 -1.01302419 -0.288072535 FBgn0005023 dpl duplicated legs http://flybase.org/reports/FBgn0005023 - gene - - - "dl, dpl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "tarsal segment,tibia" FBgn0050272 MFS1 Major Facilitator Superfamily Transporter 1 http://flybase.org/reports/FBgn0050272 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "CG11682, MFS1, CG30272" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG30272 11-Aug-17 DroID_v2017_08 "Drer\slc17a9a, Drer\slc17a6b, Drer\slc17a5, Drer\slc17a7a, Drer\slc17a6a, Drer\ppt1, Drer\slc17a8, Drer\si:ch1073-513e17.1" "Scer\TNA1, Scer\DAL5, Scer\THI73, Scer\YIL166C" "Cele\F56A4.12, Cele\K08C7.1, Cele\T28H11.8, Cele\Y4C6B.3, Cele\slc-17.9, Cele\Y19D10A.11, Cele\T22F3.8, Cele\C18H9.5, Cele\Y19D10A.8, Cele\slc-17.5, Cele\slc-17.8, Cele\cima-1, Cele\T19D12.10, Cele\Y19D10A.5, Cele\M162.5, Cele\K11G9.5, Cele\F10C2.7, Cele\Y19D10A.4, Cele\slc-17.2, Cele\T02B11.6, Cele\Y4C6B.4, Cele\vnut-1, Cele\D1046.4, Cele\T19D12.9, Cele\C39E9.7, Cele\C01B4.8, Cele\C01B4.7, Cele\slc-17.4, Cele\T27D12.1, Cele\slc-17.1, Cele\M117.1, Cele\C18D1.2, Cele\F11A5.9, Cele\Y51B9A.6, Cele\R10D12.1, Cele\vglu-2, Cele\T22F3.11, Cele\C35A5.3, Cele\F44E7.7, Cele\T22F3.7, Cele\slc-17.3, Cele\vglu-3, Cele\W04C9.6, Cele\T22F3.10, Cele\F56A4.10, Cele\F59A1.13, Cele\F41C3.2, Cele\T01H3.3, Cele\Y15E3A.4, Cele\H11E01.2, Cele\eat-4" Xtro\slc17a7 "Mmus\Slc17a6, Mmus\Slc17a3, Mmus\Slc17a8, Mmus\Slc17a2, Mmus\Slc17a4, Mmus\Slc17a7, Mmus\Slc17a1, Mmus\Slc17a5, Mmus\Slc17a9" "Hsap\SLC17A6, Hsap\SLC17A3, Hsap\SLC17A4, Hsap\SLC17A1, Hsap\SLC17A8, Hsap\SLC17A7, Hsap\SLC17A5, Hsap\SLC17A9, Hsap\SLC17A2" viable FBgn0019846 anon-XX anon-XX http://flybase.org/reports/FBgn0019846 - gene - - - "XX, anon-XX" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262339 mir-982 mir-982 stem loop http://flybase.org/reports/FBgn0262339 miRNA_gene - - - "dme-mir-982, miR-982, mir-982, CR43046, dme-miR-982" - CR43046 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible" "wing,wing margin,wing vein" FBgn0069239 gl(1)145-32 gl(1)145-32 http://flybase.org/reports/FBgn0069239 gene molecular_function ; GO:0003674 | no biological data available terminal region determination ; GO:0007362 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(1)145-32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal phenotype,germline clone,maternal effect,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryo,germline clone,maternal effect" FBgn0025511 fs(3)82EFe fs(3)82EFe http://flybase.org/reports/FBgn0025511 - gene - - - fs(3)82EFe - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0003307 rwi red wine http://flybase.org/reports/FBgn0003307 - gene - - - "rw, rwi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" pigment cell FBgn0041774 Winnebago Winnebago http://flybase.org/reports/FBgn0041774 gene - - - Winnebago - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029905 Nf-YC Nuclear factor Y-box C http://flybase.org/reports/FBgn0029905 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR027170 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR027170 axon guidance ; GO:0007411 | inferred from mutant phenotype" CCAAT-binding factor complex ; GO:0016602 | inferred from direct assay "nf-yc, CG3075, NF-YC, Nf-YC" "IPR003958:Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072:Histone-fold, IPR027170:Transcriptional activator NFYC/HAP5 subunit" CG3075 11-Aug-17 DroID_v2017_08 "Drer\chrac1, Drer\nfyc, Drer\pole4" "Scer\HAP5, Scer\DPB3" "Cele\Y53F4B.3, Cele\nfyc-1" "Xtro\pole4, Xtro\nfyc" "Mmus\Pole4, Mmus\Chrac1, Mmus\Nfyc" "Hsap\CHRAC1, Hsap\POLE4, Hsap\NFYC" "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,visible" "axon & photoreceptor cell R7 | somatic clone,lamina,axon & photoreceptor cell R7,axon & photoreceptor cell R8,wing,wing vein,supernumerary" FBgn0005309 ms(1)RD15 male sterile (1) RD15 http://flybase.org/reports/FBgn0005309 - gene - - - ms(1)RD15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,meiotic cell cycle defective" "meiotic cell cycle | male,meiotic cell cycle & spindle | male,spermatid & centriole,spermatid,meiosis I" FBgn0034085 Ptp52F Protein tyrosine phosphatase 52F http://flybase.org/reports/FBgn0034085 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay "nervous system development ; GO:0007399 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from direct assay axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with Lar protein dephosphorylation ; GO:0006470 | non-traceable author statement motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Ptp4E, Ptp10D" plasma membrane ; GO:0005886 | inferred from direct assay "DPTP52F, CT18044, CG18243, Ptp52F, PTP52F, ptp52F" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR003961:Fibronectin type III, IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR013783:Immunoglobulin-like fold, IPR003595:Protein-tyrosine phosphatase, catalytic" CG18243 11-Aug-17 DroID_v2017_08 "Drer\LOC101885876, Drer\ptprb, Drer\LOC100535694, Drer\ptprja, Drer\ptprq, Drer\ptpro, Drer\ptprjb.1, Drer\ptprjb.2, Drer\ptprh" "Scer\PTP1, Scer\PTP3, Scer\PTP2" "Cele\Y57G11C.6, Cele\ZK354.8, Cele\F20H11.4, Cele\M05D6.3, Cele\C07E3.4, Cele\ZK484.7, Cele\T28F4.3, Cele\K07F5.8, Cele\M04G7.2, Cele\hpo-7, Cele\F47B3.7, Cele\Y54F10BM.3, Cele\F36H1.3, Cele\Y71F9AL.4, Cele\B0207.1, Cele\F40G12.10, Cele\M05B5.1, Cele\T20B6.1, Cele\F57H12.5, Cele\T27A3.5, Cele\dep-1, Cele\Y22D7AR.7, Cele\Y48G1C.5, Cele\F35C11.2, Cele\Y18H1A.1, Cele\ZK809.1, Cele\K07F5.6, Cele\B0280.11, Cele\pph-2, Cele\C55B7.3, Cele\Y69A2AR.19, Cele\C17H12.3" "Xtro\ptprq, Xtro\ptpro, Xtro\ptprb" "Mmus\Ptprb, Mmus\Ptpro, Mmus\Ptprj, Mmus\Ptprh, Mmus\Ptpn23" "Hsap\PTPN23, Hsap\PTPRH, Hsap\PTPRO, Hsap\PTPRB, Hsap\PTPRJ, Hsap\PTPRQ" "neuroanatomy defective,viable" "segmental nerve branch SNa of A1-7,fascicle,central nervous system,longitudinal connective,intersegmental nerve,abdominal segmental nerve,pCC neuron,RP1 motor neuron,RP3 motor neuron,RP4 motor neuron,RP5 motor neuron,motor neuron" FBgn0045049 fs(1)259 female sterile (1) 259 http://flybase.org/reports/FBgn0045049 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)259 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg chamber,oocyte,supernumerary" FBgn0065537 l(2)SH1072 lethal (2) SH1072 http://flybase.org/reports/FBgn0065537 gene - - - "l(2)SH1072, l(2)SH2 1072" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050432 CG30432 - http://flybase.org/reports/FBgn0050432 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30432 - CG30432 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041163 aya aya http://flybase.org/reports/FBgn0041163 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available aya - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040907 mRpL33 mitochondrial ribosomal protein L33 http://flybase.org/reports/FBgn0040907 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049651 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049651 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:O75394 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9CQP0 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049651 "L33, CG3712, BcDNA:GH15938, mRpL33" IPR011332:Zinc-binding ribosomal protein CG3712 11-Aug-17 DroID_v2017_08 Drer\im:6911600 Scer\MRPL39 - - Mmus\Mrpl33 Hsap\MRPL33 "viable,visible" trichogen cell FBgn0084516 mod(mdg4)::su(Hw) mod(mdg4)::su(Hw) http://flybase.org/reports/FBgn0084516 engineered_fusion_gene - - - mod(mdg4)::su(Hw) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053912 CG33912 - http://flybase.org/reports/FBgn0053912 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33912 IPR010512:Protein of unknown function DUF1091 CG33912 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037741 CG16908 - http://flybase.org/reports/FBgn0037741 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG16908, dTti1" "IPR016024:Armadillo-type fold, IPR016441:TEL2-interacting protein 1, IPR011989:Armadillo-like helical" CG16908 11-Aug-17 DroID_v2017_08 Drer\tti1 Scer\TTI1 Cele\R10H10.7 Xtro\tti1 Mmus\Tti1 Hsap\TTI1 "lethal,viable,visible" "embryonic/larval brain,chaeta,trichogen cell" DRSC15163 K -0.024561478 0.126636288 -0.045799447 0.112178151 1.567168949 1.206019869 FBgn0013646 mfs(3)8 mfs(3)8 http://flybase.org/reports/FBgn0013646 - gene - - - mfs(3)8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female sterile" FBgn0000263 cb club http://flybase.org/reports/FBgn0000263 - gene - - - cb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "wing,sternopleural bristle" FBgn0041095 scarecrow scarecrow http://flybase.net/reports/FBgn0041095.html gene 11-Aug-17 DroID_v2017_08 FBgn0031579 CG15422 - http://flybase.org/reports/FBgn0031579 protein_coding_gene - - - CG15422 - CG15422 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0086396 BG02314 - http://flybase.org/reports/FBgn0086396 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02314 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,smell perception defective" FBgn0036619 Cpr72Ec Cuticular protein 72Ec http://flybase.org/reports/FBgn0036619 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CT15377, CG4784, Cpr72Ec" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG4784 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000542 ec echinus http://flybase.org/reports/FBgn0000542 FBgn0025376 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | NOT inferred from direct assay protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B protein deubiquitination ; GO:0016579 | inferred from electronic annotation with InterPro:IPR001394 retinal cell programmed cell death ; GO:0046666 | traceable author statement ommatidial rotation ; GO:0016318 | inferred from mutant phenotype compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype positive regulation of compound eye retinal cell programmed cell death ; GO:0046672 | inferred from mutant phenotype - "EG:EG0002.3, CG2904, ec, Ec, Q1W9Q0" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR015943:WD40/YVTN repeat-like-containing domain, IPR028889:Ubiquitin specific protease domain" CG2904 11-Aug-17 DroID_v2017_08 "Drer\usp53b, Drer\usp54a, Drer\usp54b" - - "Xtro\usp53, Xtro\usp54" "Mmus\Usp53, Mmus\Usp54" "Hsap\USP53, Hsap\USP54" "visible,recessive,decreased cell death,viable,wild-type,short lived,lethal - all die before end of pupal stage,some die during pupal stage" "eye,retina,ommatidium,wing,adult abdomen,adult thorax,dorsocentral bristle,posterior notopleural bristle,primary pigment cell,cone cell,inter-ommatidial precursor cell,supernumerary,primary pigment cell precursor" FBgn0036880 Cpr76Bc Cuticular protein 76Bc http://flybase.org/reports/FBgn0036880 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr76Bc, CG9295, DmelCpr76Bc" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG9295 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0052683 CG32683 - http://flybase.org/reports/FBgn0052683 protein_coding_gene - "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000698, InterPro:IPR014752, InterPro:IPR014753" plasma membrane ; GO:0005886 | inferred from direct assay "CG2883, CG2881, CG15303, CG32683" "IPR000698:Arrestin, IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014753:Arrestin, N-terminal, IPR014756:Immunoglobulin E-set" CG32683 11-Aug-17 DroID_v2017_08 "Drer\saga, Drer\arrb2a, Drer\arr3a, Drer\arrb2b, Drer\arrb1, Drer\arr3b, Drer\sagb" - Cele\arr-1 "Xtro\arrb2, Xtro\sag, Xtro\arr3, Xtro\arrb1" "Mmus\Arrb2, Mmus\Sag, Mmus\Arr3, Mmus\Arrb1" "Hsap\ARRB1, Hsap\ARRB2, Hsap\SAG, Hsap\ARR3" "viable,visible" trichogen cell DRSC17990 EK 0.346733423 -0.094888709 1.660604206 0.425483092 1.540212108 1.287898166 FBgn0028901 CG18109 - http://flybase.org/reports/FBgn0028901 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 microtubule minus-end binding ; GO:0051011 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin binding ; GO:0043015 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 meiotic nuclear division ; GO:0007126 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 interphase microtubule nucleation by interphase microtubule organizing center ; GO:0051415 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 centrosome duplication ; GO:0051298 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 gamma-tubulin small complex ; GO:0008275 | inferred from biological aspect of ancestor with PANTHER:PTN000447133 equatorial microtubule organizing center ; GO:0000923 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 "DS02252.3, BG:DS02252.3, CG18109" IPR007259:Gamma-tubulin complex component protein CG18109 11-Aug-17 DroID_v2017_08 Drer\tubgcp3 Scer\SPC98 - - Mmus\Tubgcp3 Hsap\TUBGCP3 FBgn0062622 Mod(var)1144 Mod(var)1144 http://flybase.org/reports/FBgn0062622 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1144, Mod(var)1144" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0263207 CR43377 - http://flybase.org/reports/FBgn0263207 pseudogene_attribute - - - CR43377 - CR43377 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001902 l(2)22Ac lethal (2) 22Ac http://flybase.org/reports/FBgn0001902 - gene - - - "l(2)neh-16, l(2)neh16, l(2)22Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001193 Hia Hiatus http://flybase.org/reports/FBgn0001193 - gene - - - Hia - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,dominant" wing vein L2 FBgn0032725 Nedd8 Nedd8 http://flybase.org/reports/FBgn0032725 protein_coding_gene protein tag ; GO:0031386 | non-traceable author statement regulation of ubiquitin-protein transferase activity ; GO:0051438 | inferred from mutant phenotype regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype protein neddylation ; GO:0045116 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P29595 "nedd8, CG10679, Nedd8, NEDD8, dNEDD8" "IPR000626:Ubiquitin domain, IPR019954:Ubiquitin conserved site, IPR019956:Ubiquitin, IPR029071:Ubiquitin-related domain" CG10679 11-Aug-17 DroID_v2017_08 "Drer\rad23aa, Drer\nedd8l, Drer\kxd1, Drer\ubc, Drer\uba52, Drer\si:ch211-202a12.4, Drer\ubb, Drer\nedd8" "Scer\RPL40B, Scer\RPL40A, Scer\RUB1" "Cele\C16C8.11, Cele\ubq-2, Cele\T28A11.22, Cele\F54D10.7, Cele\ned-8, Cele\kxd-1, Cele\F52C6.2, Cele\F52C6.3" "Xtro\rps27a, Xtro\uba52, Xtro\kxd1, Xtro\nedd8, Xtro\ubc" "Mmus\Ubd, Mmus\Rps27a, Mmus\Ubb, Mmus\Isg15, Mmus\Ubc, Mmus\Nedd8, Mmus\Rad23b" "Hsap\RAD23B, Hsap\UBA52, Hsap\UBB, Hsap\UBD, Hsap\NEDD8, Hsap\ISG15, Hsap\NEDD8-MDP1, Hsap\RAD23A, Hsap\UBC, Hsap\RPS27A" "lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,female sterile,germline clone,sleep defective" "embryonic/larval salivary gland,adult mushroom body,eye disc,somatic clone,neuron & gamma-lobe,ovary,germline clone,embryonic/larval neuroblast,ganglion mother cell" DRSC02092 E 0.900720889 0.817908229 1.97614075 1.156351074 0.111308176 0.509694476 FBgn0069191 l(3)c00014 lethal (3) c00014 http://flybase.org/reports/FBgn0069191 gene - - - l(3)c00014 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260492 l(3)3456 - http://flybase.org/reports/FBgn0260492 gene - axonogenesis ; GO:0007409 | inferred from mutant phenotype - l(3)3456 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,axon" FBgn0053311 CG33311 - http://flybase.org/reports/FBgn0053311 protein_coding_gene - - - CG33311 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005727 l(1)TK202 lethal (1) TK202 http://flybase.org/reports/FBgn0005727 - gene - - - "l202, l(1)TK202" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036321 CG14120 - http://flybase.org/reports/FBgn0036321 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - CG14120 "IPR001604:DNA/RNA non-specific endonuclease, IPR020821:Extracellular Endonuclease, subunit A" CG14120 11-Aug-17 DroID_v2017_08 "Drer\LOC100333474, Drer\endog, Drer\LOC103910196" Scer\NUC1 Cele\cps-6 - Mmus\Endog Hsap\ENDOG viable FBgn0267639 CR45977 - http://flybase.org/reports/FBgn0267639 non_protein_coding_gene - - - CR45977 - CR45977 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045052 fs(1)234 female sterile (1) 234 http://flybase.org/reports/FBgn0045052 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)234 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "germline cell,follicle cell" FBgn0037560 CR18228 - http://flybase.org/reports/FBgn0037560 pseudogene_attribute - - - "CG18228, CR18228" - CR18228 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0265549 CR44399 - http://flybase.org/reports/FBgn0265549 non_protein_coding_gene - - - "CR44399, lincRNA.176" - CR44399 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050016 CG30016 - http://flybase.org/reports/FBgn0050016 protein_coding_gene hydroxyisourate hydrolase activity ; GO:0033971 | inferred from electronic annotation with InterPro:IPR014306 purine nucleobase metabolic process ; GO:0006144 | inferred from biological aspect of ancestor with PANTHER:PTN000044586 - "anon-AE003828.1, CG30016" "IPR000895:Transthyretin/hydroxyisourate hydrolase, IPR014306:Hydroxyisourate hydrolase, IPR023416:Transthyretin/hydroxyisourate hydrolase, superfamily" CG30016 11-Aug-17 DroID_v2017_08 "Drer\urah, Drer\LOC570474, Drer\ttr" - "Cele\R09H10.3, Cele\ZK697.8" "Xtro\ttr, Xtro\urah" "Mmus\Ttr, Mmus\Urah" Hsap\TTR "viable,fertile" FBgn0266116 CR44842 - http://flybase.org/reports/FBgn0266116 non_protein_coding_gene - - - CR44842 - CR44842 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031276 CG12506 - http://flybase.org/reports/FBgn0031276 protein_coding_gene - - - "CG12506, cg12506" - CG12506 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" FBgn0052194 CR32194 - http://flybase.org/reports/FBgn0052194 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE06388, CG32194, CR32194" - CR32194 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032217 CG4972 - http://flybase.org/reports/FBgn0032217 protein_coding_gene - regulation of signal transduction ; GO:0009966 | inferred from biological aspect of ancestor with PANTHER:PTN000782122 endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000782122 "CG4972, Q9VKZ7_DROME" IPR016574:Nicalin CG4972 11-Aug-17 DroID_v2017_08 "Drer\ncl1, Drer\zgc:109965" - Cele\nra-2 Xtro\ncln Mmus\Ncln Hsap\NCLN "viable,fertile" FBgn0053137 CG33137 - http://flybase.org/reports/FBgn0053137 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4023, CG33137" IPR010512:Protein of unknown function DUF1091 CG33137 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032408 CG6712 - http://flybase.org/reports/FBgn0032408 protein_coding_gene rRNA primary transcript binding ; GO:0042134 | inferred from biological aspect of ancestor with PANTHER:PTN000506776 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:Q9H9Y2 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with SGD:S000001130 maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000506777 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000506777 ribosome biogenesis ; GO:0042254 | inferred from sequence or structural similarity with SGD:S000001130 maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000506777 "nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000506776 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000506777 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q9H9Y2 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with SGD:S000001130" "ORF2, CG6712" "IPR007109:Brix domain, IPR004154:Anticodon-binding" CG6712 11-Aug-17 DroID_v2017_08 Drer\rpf1 Scer\RPF1 Cele\F44G4.1 Xtro\rpf1 Mmus\Rpf1 Hsap\RPF1 " adult stage | female , embryonic stage , embryonic stage | early , adult stage && oogenesis stage | stage S10 " " neuroblast

, embryonic digestive system

, ovary

, organism | ubiquitous

, nurse cell

" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC21690 E 0.792483366 -0.565693137 1.795607302 -0.114702031 -0.782523078 0.358861328 FBgn0266913 CR45373 - http://flybase.org/reports/FBgn0266913 non_protein_coding_gene - - - CR45373 - CR45373 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037117 CG11248 - http://flybase.org/reports/FBgn0037117 protein_coding_gene - - - CG11248 - CG11248 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0263040 CG43335 - http://flybase.org/reports/FBgn0263040 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model with InterPro:IPR001254" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model with InterPro:IPR001254" cellular_component ; GO:0005575 | no biological data available "CG43335, CG5302, SPH73" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan" CG43335 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.9, Drer\si:ch211-165b19.5, Drer\gzm3, Drer\si:dkey-21e2.15, Drer\si:dkey-21e2.12, Drer\si:dkey-21e2.7" - - - "Mmus\Mcpt9, Mmus\Gzmb, Mmus\Gzmg, Mmus\Klk6, Mmus\Mcpt1, Mmus\Cma1, Mmus\Mcpt8, Mmus\Cma2, Mmus\Mcpt4, Mmus\Gzmc, Mmus\Gzme, Mmus\Ctsg, Mmus\Gzmd, Mmus\Gzmf" "Hsap\CTSG, Hsap\GZMH, Hsap\CMA1, Hsap\GZMB" "partially lethal - majority die,some die during pupal stage" FBgn0019752 l(1)815-22 lethal (1) 815-22 http://flybase.org/reports/FBgn0019752 - gene - - - l(1)815-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010145 l(3)62Bj lethal (3) 62Bj http://flybase.org/reports/FBgn0010145 - gene - - - "dre7, l(3)dre7, l(3)62Bj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0000624 Eye Eyeless dominant on 2 http://flybase.org/reports/FBgn0000624 - gene - - - "ey-II[D], Eye" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "eye,antenna" FBgn0036403 CG6661 - http://flybase.org/reports/FBgn0036403 protein_coding_gene 1-pyrroline-5-carboxylate dehydrogenase activity ; GO:0003842 | inferred from sequence or structural similarity with UniProtKB:P30038 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163 proline metabolic process ; GO:0006560 | inferred from sequence or structural similarity with UniProtKB:P30038" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P30038 "PUT2, CG6661, CR33944" "IPR015590:Aldehyde dehydrogenase domain, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain" CG6661 11-Aug-17 DroID_v2017_08 "Drer\aldh4a1, Drer\iffo2a" Scer\PUT2 Cele\alh-6 Xtro\aldh4a1 "Mmus\Iffo2, Mmus\Aldh4a1" "Hsap\IFFO2, Hsap\ALDH4A1" viable FBgn0051216 Naam Nicotinamide amidase http://flybase.org/reports/FBgn0051216 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 nicotinamidase activity ; GO:0008936 | inferred from direct assay metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000868 negative regulation of neuron apoptotic process ; GO:0043524 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype - "AAM52663, CG7500, CG7444, anon-WO0172774.60, anon-WO0172774.59, D-NAAM, Naam, CG31216" "IPR000868:Isochorismatase-like, IPR002048:EF-hand domain, IPR018247:EF-Hand 1, calcium-binding site, IPR011992:EF-hand domain pair" CG31216 11-Aug-17 DroID_v2017_08 - Scer\PNC1 "Cele\pnc-1, Cele\pnc-2" - - - "long lived,viable,auditory perception defective" FBgn0053318 CR33318 - http://flybase.org/reports/FBgn0053318 pseudogene_attribute - - - "CR33318, CG18078" - CR33318 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260038 33AA12 - http://flybase.org/reports/FBgn0260038 gene - - - 33AA12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0267994 CR46261 - http://flybase.org/reports/FBgn0267994 non_protein_coding_gene - - - CR46261 - CR46261 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040296 Ocho Ocho http://flybase.org/reports/FBgn0040296 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with neur ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000262353 "cell fate specification ; GO:0001708 | inferred from biological aspect of ancestor with PANTHER:PTN000262353 sensory organ development ; GO:0007423 | inferred from biological aspect of ancestor with PANTHER:PTN000262353 Notch signaling pathway ; GO:0007219 | inferred from biological aspect of ancestor with PANTHER:PTN000262353 sensory organ development ; GO:0007423 | inferred from sequence or structural similarity with Brd, E(spl)m4-BFM, Tom Notch signaling pathway ; GO:0007219 | inferred from sequence or structural similarity with Brd, E(spl)m4-BFM, Tom" - "CG5138, CG3396, Ocho, ocho, DmelCG3396" IPR029686:Enhancer of split M4 family CG3396 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020867 auk auk http://flybase.org/reports/FBgn0020867 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "gon, auk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "wing,somatic clone" FBgn0003503 srd small round http://flybase.org/reports/FBgn0003503 - gene - - - srd - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,eye color defective" "eye,pigment cell,postvertical bristle" FBgn0027127 l(3)H94 lethal (3) H94 http://flybase.org/reports/FBgn0027127 - gene - - - l(3)H94 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004074 ovt ovarian tumor at 37D-38A http://flybase.org/reports/FBgn0004074 - gene - - - ovt - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" FBgn0264736 ato::Bmor\ato - http://flybase.org/reports/FBgn0264736 engineered_fusion_gene - - - ato::Bmor\ato - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264526 ff27 - http://flybase.org/reports/FBgn0264526 gene - - - ff27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male" spermatid FBgn0038732 CG11391 - http://flybase.org/reports/FBgn0038732 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG11391 "IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site, IPR025110:AMP-binding enzyme C-terminal domain" CG11391 11-Aug-17 DroID_v2017_08 "Drer\acsf3, Drer\acsbg1" Scer\PCS60 "Cele\acs-7, Cele\acs-9, Cele\acs-10, Cele\C32E8.6, Cele\acs-6, Cele\C25G6.3, Cele\mec-18, Cele\acs-12, Cele\acs-14, Cele\acs-20" Xtro\acsf3 "Mmus\Slc27a4, Mmus\Acsbg1, Mmus\Acsf3" "Hsap\ACSF3, Hsap\ACSBG1, Hsap\SLC27A4" "viable,fertile" FBgn0060452 l(3)S119607b lethal (3) S119607b http://flybase.org/reports/FBgn0060452 gene - - - "1196/07, l(3)S119607b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264913 CG44104 - http://flybase.org/reports/FBgn0264913 protein_coding_gene - - - CG44104 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033422 Or45b Odorant receptor 45b http://flybase.org/reports/FBgn0033422 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "CG12931, 45b, DOR107, 45F.1, Or45b" "IPR004117:Olfactory receptor, insect" CG12931 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,viable" FBgn0033358 spab space blanket http://flybase.org/reports/FBgn0033358 protein_coding_gene molecular_function ; GO:0003674 | no biological data available detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG8216, spab" - CG8216 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001037 fs(3)G5 female sterile (3) G5 http://flybase.org/reports/FBgn0001037 - gene - - - "fs(3)5, fs(3)G5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male fertile" "ovariole,egg chamber" FBgn0035517 CG1265 - http://flybase.org/reports/FBgn0035517 protein_coding_gene - dolichol-linked oligosaccharide biosynthetic process ; GO:0006488 | inferred from biological aspect of ancestor with PANTHER:PTN000259900 - "BcDNA:RE09466, CG1265" "IPR016817:Mannose-P-dolichol utilization defect 1 protein, IPR006603:PQ-loop repeat" CG1265 11-Aug-17 DroID_v2017_08 "Drer\mpdu1a, Drer\pqlc3, Drer\mpdu1b" - Cele\F38E1.9 "Xtro\mpdu1, Xtro\pqlc3" "Mmus\Pqlc3, Mmus\Mpdu1" "Hsap\MPDU1, Hsap\PQLC3" viable embryonic/larval hemocyte | third instar larval stage FBgn0069991 BG01950 BG01950 http://flybase.org/reports/FBgn0069991 gene - - - BG01950 - - 11-Aug-17 DroID_v2017_08 - - - - - - "stress response defective,long lived,female limited,short lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0001742 l(1)HM12 lethal (1) HM12 http://flybase.org/reports/FBgn0001742 - gene - - - l(1)HM12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0039897 CG1674 - http://flybase.org/reports/FBgn0039897 protein_coding_gene actin binding ; GO:0003779 | inferred from biological aspect of ancestor with PANTHER:PTN001198415 positive regulation of actin filament bundle assembly ; GO:0032233 | inferred from biological aspect of ancestor with PANTHER:PTN001198415 actin cytoskeleton ; GO:0015629 | inferred from biological aspect of ancestor with PANTHER:PTN001198415 Z disc ; GO:0030018 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001198415 CG1674 - CG1674 11-Aug-17 DroID_v2017_08 "Drer\synpo2b, Drer\synpo2la, Drer\synpo2lb" - - - "Mmus\Synpo2l, Mmus\Synpo, Mmus\Synpo2" "Hsap\SYNPO, Hsap\SYNPO2L, Hsap\SYNPO2" viable FBgn0016831 l(1)MZ18 lethal (1) MZ18 http://flybase.org/reports/FBgn0016831 - gene - - - "l(1)MZ18, M18" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029708 CG3556 - http://flybase.org/reports/FBgn0029708 protein_coding_gene cobalamin binding ; GO:0031419 | inferred from electronic annotation with InterPro:IPR002157 cobalamin transport ; GO:0015889 | inferred from electronic annotation with InterPro:IPR002157 cellular_component ; GO:0005575 | no biological data available CG3556 "IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR002157:Cobalamin (vitamin B12)-binding transporter, eukaryotic" CG3556 11-Aug-17 DroID_v2017_08 Drer\tcn2 - - - "Mmus\Gif, Mmus\Tcn2" "Hsap\TCN1, Hsap\TCN2, Hsap\GIF" "viable,fertile" FBgn0015951 jnh jekyll and hyde http://flybase.org/reports/FBgn0015951 - gene - - - jnh - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261999 CG42817 - http://flybase.org/reports/FBgn0261999 protein_coding_gene - - - "CG42817, CG12455, DS07473.1A, BG:DS07473.1" "IPR013608:VWA N-terminal, IPR002035:von Willebrand factor, type A, IPR013680:Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region" CG42817 11-Aug-17 DroID_v2017_08 "Drer\cacna2d4a, Drer\cacna2d2a, Drer\cacna2d4b, Drer\cacna2d3, Drer\cacna2d2b, Drer\cacna2d1a, Drer\cachd1" - "Cele\unc-36, Cele\tag-180" "Xtro\cacna2d2, Xtro\cachd1, Xtro\cacna2d1, Xtro\cacna2d4" "Mmus\Cachd1, Mmus\Cacna2d3, Mmus\Cacna2d1, Mmus\Cacna2d4, Mmus\Cacna2d2" "Hsap\CACNA2D3, Hsap\CACNA2D2, Hsap\CACHD1, Hsap\CACNA2D4, Hsap\CACNA2D1" "viable,fertile" FBgn0085667 CG41522 - http://flybase.org/reports/FBgn0085667 protein_coding_gene - - - CG41522 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266839 CR45301 - http://flybase.org/reports/FBgn0266839 non_protein_coding_gene - - - CR45301 - CR45301 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031080 CG12655 - http://flybase.org/reports/FBgn0031080 protein_coding_gene - - - CG12655 - CG12655 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" DRSC20678 K -0.322108592 0.608937546 0.392324931 0.316238674 -2.160465362 -0.060984946 FBgn0003702 tht thickset http://flybase.org/reports/FBgn0003702 - gene - - - tht - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,viable,male,poor,visible" "eye,ommatidium" FBgn0029087 enPRE engrailed Polycomb group response element http://flybase.org/reports/FBgn0029087 regulatory_region - - - "enPRE, en PRE" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001035 fs(3)G2 female sterile (3) G2 http://flybase.org/reports/FBgn0001035 - gene - - - "fs(3)2, fs(3)G2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male sterile,partially,viable,poor,male semi-sterile" "egg chamber,oocyte" FBgn0031043 Naa20A N(alpha)-acetyltransferase 20 A http://flybase.org/reports/FBgn0031043 protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from biological aspect of ancestor with PANTHER:PTN000558065 N-terminal peptidyl-methionine acetylation ; GO:0017196 | inferred from biological aspect of ancestor with PANTHER:PTN000558099 histone acetylation ; GO:0016573 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from genetic interaction with psidin NatB complex ; GO:0031416 | inferred from direct assay NatB complex ; GO:0031416 | inferred from biological aspect of ancestor with PANTHER:PTN000558099 "CG14222, DmAAF48987, dNAA20, Naa20, Naa20A, NAA20" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG14222 11-Aug-17 DroID_v2017_08 Drer\naa20 Scer\NAT3 Cele\Y97E10AL.3 Xtro\naa20 Mmus\Naa20 Hsap\NAA20 "viable,visible" mesothoracic tergum FBgn0062656 EP339 EP339 http://flybase.org/reports/FBgn0062656 gene - - - "EP(3)0339, EP339" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036600 CG13043 - http://flybase.org/reports/FBgn0036600 protein_coding_gene - - - "CT32262, BcDNA:RH10371, CG13043" IPR007614:Retinin-like protein CG13043 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0085669 CG41526 - http://flybase.org/reports/FBgn0085669 protein_coding_gene - - - CG41526 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032750 CG10495 - http://flybase.org/reports/FBgn0032750 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517 tRNA dihydrouridine synthase activity ; GO:0017150 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517" - "anon-WO0118547.200, CG10495" "IPR018517:tRNA-dihydrouridine synthase, conserved site, IPR001269:tRNA-dihydrouridine synthase, IPR013785:Aldolase-type TIM barrel" CG10495 11-Aug-17 DroID_v2017_08 "Drer\dus1l, Drer\dus4l" "Scer\DUS1, Scer\DUS4" Cele\C45G9.2 "Xtro\dus1l, Xtro\dus4l" "Mmus\Dus1l, Mmus\Dus4l" "Hsap\DUS1L, Hsap\DUS4L" FBgn0032520 CG10859 - http://flybase.org/reports/FBgn0032520 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:Q9GZS0 outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q9GZS0 CG10859 "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG10859 11-Aug-17 DroID_v2017_08 "Drer\LOC103908626, Drer\dync1i1, Drer\dnai1.1, Drer\dnai2b, Drer\dync1i2b, Drer\dnai2a" - Cele\prp-17 "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Dnaic2, Mmus\Wdr63, Mmus\Dync1i2, Mmus\Dync1i1" "Hsap\DYNC1I2, Hsap\DYNC1I1, Hsap\WDR60, Hsap\DNAI2" viable FBgn0005010 Din Dinty http://flybase.org/reports/FBgn0005010 - gene - - - Din - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,viable,fertile" "wing vein L2,supraalar bristle,anterior postalar bristle,wing" FBgn0265751 CR44558 - http://flybase.org/reports/FBgn0265751 non_protein_coding_gene - - - "CR44558, lincRNA.543" - CR44558 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033667 reb rebuf http://flybase.org/reports/FBgn0033667 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001132 trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype cuticle chitin biosynthetic process ; GO:0006035 | inferred from mutant phenotype chitin biosynthetic process ; GO:0006031 | inferred from mutant phenotype" apical part of cell ; GO:0045177 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG13183, reb" "IPR001132:SMAD domain, Dwarfin-type, IPR008984:SMAD/FHA domain, IPR017855:SMAD domain-like" CG13183 11-Aug-17 DroID_v2017_08 - - Cele\C34E11.2 - - - viable FBgn0265340 CR44294 - http://flybase.org/reports/FBgn0265340 non_protein_coding_gene - - - CR44294 - CR44294 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050088 CG30088 - http://flybase.org/reports/FBgn0050088 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP41, CG8215, CG30088" "IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR033116:Serine proteases, trypsin family, serine active site" CG30088 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.5, Drer\si:dkey-21e2.12, Drer\f9a, Drer\si:dkey-21e2.7, Drer\si:ch211-165b19.9, Drer\si:dkey-21e2.15, Drer\gzm3, Drer\st14b, Drer\masp2" - "Cele\try-1, Cele\try-3, Cele\svh-1" - "Mmus\Ctsg, Mmus\Cma1, Mmus\Mcpt8, Mmus\Mcpt9, Mmus\Gzmg, Mmus\Mcpt1, Mmus\Gzmc, Mmus\Mcpt4, Mmus\Gzmf, Mmus\Cma2, Mmus\Gzmd, Mmus\Klk6, Mmus\Gzme, Mmus\Gzmb" "Hsap\CMA1, Hsap\GZMH, Hsap\GZMB, Hsap\CTSG" viable DRSC24797 K -0.160133368 -0.036267953 -0.530845363 -0.751119297 -3.224469765 0.838176669 FBgn0265689 CR44496 - http://flybase.org/reports/FBgn0265689 non_protein_coding_gene - - - CR44496 - CR44496 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267989 CR46256 - http://flybase.org/reports/FBgn0267989 non_protein_coding_gene - - - CR46256 - CR46256 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036260 Rh7 Rhodopsin 7 http://flybase.org/reports/FBgn0036260 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from biological aspect of ancestor with PANTHER:PTN001200938 G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with Rh3 neuropeptide binding ; GO:0042923 | inferred from biological aspect of ancestor with PANTHER:PTN000659780 "visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR001760 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger ; GO:0007187 | inferred from biological aspect of ancestor with PANTHER:PTN001200938 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with Rh3 neuropeptide signaling pathway ; GO:0007218 | inferred from biological aspect of ancestor with PANTHER:PTN000659780" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001200938 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Rh3 neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN001200938 "Rh, CG5638, rh7, DMELRH7, anon-WO0170980.35, anon-WO0170980.34, Rh7" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001760:Opsin, IPR017452:GPCR, rhodopsin-like, 7TM, IPR027430:Visual pigments (opsins) retinal binding site" CG5638 11-Aug-17 DroID_v2017_08 "Drer\oprl1, Drer\sstr2a, Drer\opn5, Drer\opn7b, Drer\tmtopsb, Drer\opn8b, Drer\si:dkey-42l23.2, Drer\opn6a, Drer\opn7d, Drer\sstr2b, Drer\oprd1b, Drer\tmtops2b, Drer\opn1lw1, Drer\opn4xa, Drer\opn4xb, Drer\gpr1, Drer\LOC100005512, Drer\LOC571123, Drer\oprm1, Drer\LOC100333697, Drer\opn1mw3, Drer\valopa, Drer\opn6b, Drer\LOC100334739, Drer\sstr1a, Drer\sstr1b, Drer\opn7c, Drer\rho, Drer\opn1sw1, Drer\tmtopsa, Drer\opn4b, Drer\tmtops3b, Drer\parapinopsinb, Drer\LOC101883086, Drer\rhol, Drer\valopb, Drer\zgc:194202, Drer\opn1lw2, Drer\opn7a, Drer\sstr3, Drer\oprd1a, Drer\opn1mw4, Drer\oprk1, Drer\opn9, Drer\tmtops2a, Drer\sstr5, Drer\opn1sw2, Drer\opn4.1, Drer\opn8c, Drer\opn4a, Drer\opn3, Drer\exorh, Drer\tmtops3a, Drer\parietopsin, Drer\opn1mw1, Drer\rrh" - "Cele\F09C12.6, Cele\srsx-34, Cele\npr-18, Cele\F36D4.4, Cele\srsx-2, Cele\npr-24, Cele\npr-16, Cele\srsx-1" "Xtro\LOC100485437, Xtro\tmtops, Xtro\opn5, Xtro\rho, Xtro\opn1lw, Xtro\tmtops.2, Xtro\LOC100124934, Xtro\opn1sw, Xtro\LOC100485989, Xtro\rrh" "Mmus\Sstr1, Mmus\Olfr9, Mmus\Oprm1, Mmus\Sstr4, Mmus\Olfr1447, Mmus\Olfr763, Mmus\Sstr5, Mmus\Oprk1, Mmus\Olfr32, Mmus\Olfr513, Mmus\Ptgdr2, Mmus\Gpr1, Mmus\Opn5, Mmus\Olfr1353, Mmus\Olfr290, Mmus\Opn4, Mmus\Olfr1413, Mmus\Sstr2, Mmus\Olfr1163, Mmus\Sstr3, Mmus\Npbwr1, Mmus\Oprd1, Mmus\Opn3, Mmus\Olfr1411, Mmus\Olfr70, Mmus\Olfr299, Mmus\Oprl1, Mmus\Olfr1446, Mmus\Rho, Mmus\Olfr1461, Mmus\Opn1mw, Mmus\Olfr1105, Mmus\Olfr1162, Mmus\Olfr291, Mmus\Olfr12, Mmus\Olfr67, Mmus\Opn1sw, Mmus\Rrh, Mmus\Gpr149, Mmus\Olfr1467" "Hsap\RRH, Hsap\OPRL1, Hsap\OR5B17, Hsap\OPN4, Hsap\SSTR5, Hsap\OPN5, Hsap\OPN1MW, Hsap\OR7C2, Hsap\NPBWR2, Hsap\SSTR4, Hsap\OPN3, Hsap\OPN1MW3, Hsap\GPR1, Hsap\OPN1MW2, Hsap\SSTR1, Hsap\OPRK1, Hsap\OR5B2, Hsap\SSTR3, Hsap\OPN1SW, Hsap\OPRD1, Hsap\SSTR2, Hsap\PTGDR2, Hsap\GPR149, Hsap\RHO, Hsap\NPBWR1, Hsap\OR7C1, Hsap\OPRM1, Hsap\OPN1LW" viable FBgn0022144 l(2)k06107 lethal (2) k06107 http://flybase.org/reports/FBgn0022144 - gene - - - l(2)k06107 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040785 CG12554 - http://flybase.org/reports/FBgn0040785 protein_coding_gene - - - CG12554 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267223 CR45663 - http://flybase.org/reports/FBgn0267223 non_protein_coding_gene - - - CR45663 - CR45663 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044077 E(rst)H94 E(rst)H94 http://flybase.org/reports/FBgn0044077 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H94, E(rst)H94" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0000686 l(1)adl16 lethal (1) adl16 http://flybase.org/reports/FBgn0000686 FBgn0010122 gene - - - "l(1)adl-16, l(1)DC836, l(1)DC359, flrdI, l(1)adl16" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,visible,short lived" "proboscis,heat sensitive,adult abdomen" FBgn0041168 anon-A3 anon-A3 http://flybase.org/reports/FBgn0041168 gene - - - "A3, anon-A3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024610 olf702 olfactory 702 http://flybase.org/reports/FBgn0024610 - gene - - - olf702 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015829 TfIIEbeta Transcription factor IIEbeta http://flybase.org/reports/FBgn0015829 - protein_coding_gene - positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4651 inferred from sequence or structural similarity with SGD:S000001770 inferred from sequence or structural similarity with protein_id:CAA70049.1 transcription factor TFIIE complex ; GO:0005673 | inferred from sequence or structural similarity with HGNC:4651 inferred from sequence or structural similarity with SGD:S000001770 inferred from sequence or structural similarity with protein_id:CAA70049.1 nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIIE complex ; GO:0005673 | inferred from physical interaction with TfIIEα "TFIIE, E[[S]], CG1276, dTFIIES, dTFIIE-S, TfIIE, TfIIEbeta, TFIIEbeta, TFIIbeta" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016656:Transcription initiation factor TFIIE, beta subunit, IPR003166:Transcription factor TFIIE beta subunit, DNA-binding domain" CG1276 11-Aug-17 DroID_v2017_08 Drer\gtf2e2 Scer\TFA2 Cele\F54D5.11 Xtro\gtf2e2 Mmus\Gtf2e2 Hsap\GTF2E2 "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0023524 CG3078 - http://flybase.org/reports/FBgn0023524 - protein_coding_gene potassium channel regulator activity ; GO:0015459 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 regulation of muscle contraction ; GO:0006937 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 regulation of potassium ion transport ; GO:0043266 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 striated muscle dense body ; GO:0055120 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 "EG:30B8.6, CG3078" IPR020846:Major facilitator superfamily domain CG3078 11-Aug-17 DroID_v2017_08 "Drer\unc93a, Drer\unc93b1" - Cele\unc-93 Xtro\unc93b1 "Mmus\Gm9992, Mmus\Unc93b1, Mmus\Unc93a" "Hsap\UNC93A, Hsap\UNC93B1" DRSC18531 E -0.041557708 -0.845271116 -2.186401317 -0.522114799 -0.829104816 -0.612514432 FBgn0044010 Su(rst)B16 Su(rst)B16 http://flybase.org/reports/FBgn0044010 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B16, Su(rst)B16" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0034456 Ir56b Ionotropic receptor 56b http://flybase.org/reports/FBgn0034456 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir56b, DmelIR56b, CG15121, IR56b" - CG15121 11-Aug-17 DroID_v2017_08 - - Cele\glr-7 - - "Hsap\GRID1, Hsap\GRID2" viable DRSC06543 K 0.787165879 0.054280992 0.40471128 0.024213006 -0.778892273 -2.013111928 FBgn0263652 CR43643 - http://flybase.org/reports/FBgn0263652 non_protein_coding_gene - - - CR43643 - CR43643 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266704 CR45194 - http://flybase.org/reports/FBgn0266704 non_protein_coding_gene - - - CR45194 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036169 Fuca alpha-L-fucosidase http://flybase.org/reports/FBgn0036169 protein_coding_gene "alpha-L-fucosidase activity ; GO:0004560 | inferred from electronic annotation with InterPro:IPR000933, InterPro:IPR016286 alpha-L-fucosidase activity ; GO:0004560 | traceable author statement fucose binding ; GO:0042806 | inferred from direct assay" fucose metabolic process ; GO:0006004 | inferred from electronic annotation with InterPro:IPR016286 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype glycosaminoglycan catabolic process ; GO:0006027 | non-traceable author statement cytoplasm ; GO:0005737 | inferred by curator from GO:0004560 "CG6128, CG33047, Fuca, Fuca_Dm, DmFuca" "IPR000933:Glycoside hydrolase, family 29, IPR016286:Alpha-L-fucosidase, metazoa-type, IPR017853:Glycoside hydrolase superfamily, IPR031919:Alpha-L-fucosidase, C-terminal" CG6128 11-Aug-17 DroID_v2017_08 "Drer\fuca1.1, Drer\fuca1.2, Drer\fuca2" - Cele\W03G11.3 Xtro\fuca2 "Mmus\Fuca2, Mmus\Fuca1" "Hsap\FUCA2, Hsap\FUCA1" "viable,fertile" FBgn0015366 bnd-35 bnd-35 http://flybase.org/reports/FBgn0015366 - gene - - - bnd-35 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014454 Acp1 Adult cuticle protein 1 http://flybase.org/reports/FBgn0014454 - protein_coding_gene - - - "Dacp-1, CG7216, Acp1, CG7216-PA, acp1" IPR031874:Adult cuticle protein 1 CG7216 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " epidermis &&of adult head

, epidermis &&of adult thorax

" FBgn0022742 anon-UJB6 anon-UJB6 http://flybase.org/reports/FBgn0022742 - gene - - - anon-UJB6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031318 CG4887 - http://flybase.org/reports/FBgn0031318 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467, InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity" "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "cg4887, CG4887" "IPR000467:G-patch domain, IPR000504:RNA recognition motif domain, IPR001876:Zinc finger, RanBP2-type, IPR013087:Zinc finger C2H2-type" CG4887 11-Aug-17 DroID_v2017_08 "Drer\LOC567058, Drer\rbm10, Drer\rbm5, Drer\aggf1" - Cele\T08B2.5 "Xtro\rbm5, Xtro\aggf1" "Mmus\Rbm10, Mmus\Rbm6, Mmus\Rbm5, Mmus\Gpatch2" "Hsap\RBM10, Hsap\RBM5, Hsap\RBM6" "viable,visible" trichogen cell FBgn0024694 en::ftz::Mmus\En1 en::ftz::Mmus\En1 http://flybase.org/reports/FBgn0024694 - engineered_fusion_gene - - - "en::ftz::Mus\En1, en::ftz::Mmus\En1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" denticle belt FBgn0004194 snRNA:U2:84Cb small nuclear RNA U2 at 84Cb http://flybase.org/reports/FBgn0004194 "FBgn0003919, FBgn0003924" snRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "snRNA:U2, U2snRNA84Cb, U2snRNA, snRNA:U2:84Cb, U2, dU2, U2 snRNA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265515 su(comt[6])S14 suppressor of comatose[6] S14 http://flybase.org/reports/FBgn0265515 gene - - - su(comt[6])S14 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067773 fragile-locus-C fragile locus C http://flybase.org/reports/FBgn0067773 gene molecular_function ; GO:0003674 | no biological data available egg activation ; GO:0007343 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fragile-locus-C - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect" FBgn0260035 32C40 - http://flybase.org/reports/FBgn0260035 gene - - - 32C40 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0035430 CG12009 - http://flybase.org/reports/FBgn0035430 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG12009 IPR002557:Chitin binding domain CG12009 11-Aug-17 DroID_v2017_08 - - "Cele\C50F2.2, Cele\Y56A3A.6" - - - viable FBgn0262902 CR43257 - http://flybase.org/reports/FBgn0262902 non_protein_coding_gene - - - CR43257 - CR43257 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014466 Cp7Fc Chorion protein c at 7F http://flybase.org/reports/FBgn0014466 FBgn0030045 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern inferred from genomic context chorion ; GO:0042600 | inferred from genomic context inferred by curator from GO:0007304 "Cp7Fc, CG15351, E, D, s37" - CG15351 11-Aug-17 DroID_v2017_08 - - Cele\C26F1.1 - - - " oogenesis stage | stage S11-12 , adult stage | female && oogenesis stage | stage S10-13 , adult stage && oogenesis stage | stage S10B-13 " "

, organism

, follicle cell

" viable FBgn0031903 Wnt10 Wnt oncogene analog 10 http://flybase.org/reports/FBgn0031903 protein_coding_gene receptor binding ; GO:0005102 | inferred from sequence or structural similarity with wg frizzled binding ; GO:0005109 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 cell fate commitment ; GO:0045165 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 neuron differentiation ; GO:0030182 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 Wnt signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with wg Wnt signaling pathway ; GO:0016055 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with wg extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 "DWnt10, DWnt-10, CG4971, Wnt10, D-Wnt-10, wnt10, Dm DWnt10" "IPR018161:Wnt protein, conserved site, IPR005817:Wnt" CG4971 11-Aug-17 DroID_v2017_08 "Drer\wnt10a, Drer\wnt9a, Drer\wnt7ba, Drer\wnt10b, Drer\wnt16, Drer\wnt8b, Drer\wnt2ba, Drer\wnt1, Drer\wnt9b, Drer\wnt7bb, Drer\wnt7aa, Drer\wnt5a, Drer\wnt11, Drer\wnt6b, Drer\wnt3a, Drer\wnt4b, Drer\wnt2, Drer\wnt2bb, Drer\LOC568110, Drer\wnt3, Drer\wnt11r, Drer\wnt5b, Drer\wnt6a, Drer\wnt8a, Drer\wnt4a" - "Cele\egl-20, Cele\cwn-1, Cele\mom-2, Cele\cwn-2" "Xtro\wnt8b, Xtro\wnt9b, Xtro\wnt11, Xtro\wnt2b, Xtro\wnt1, Xtro\wnt7a, Xtro\wnt7c, Xtro\wnt11r, Xtro\wnt16, Xtro\wnt10b, Xtro\wnt5b, Xtro\wnt9b.2, Xtro\wnt3a, Xtro\wnt4, Xtro\wnt7b, Xtro\wnt8a" "Mmus\Wnt11, Mmus\Wnt8b, Mmus\Wnt8a, Mmus\Wnt9b, Mmus\Wnt16, Mmus\Wnt7a, Mmus\Wnt10a, Mmus\Wnt7b, Mmus\Wnt2b, Mmus\Wnt5b, Mmus\Wnt9a, Mmus\Wnt6, Mmus\Wnt3, Mmus\Wnt1, Mmus\Wnt4, Mmus\Wnt3a, Mmus\Wnt2, Mmus\Wnt10b, Mmus\Wnt5a" "Hsap\WNT4, Hsap\WNT3, Hsap\WNT8B, Hsap\WNT10A, Hsap\WNT5A, Hsap\WNT6, Hsap\WNT11, Hsap\WNT9B, Hsap\WNT9A, Hsap\WNT2B, Hsap\WNT7B, Hsap\WNT10B, Hsap\WNT3A, Hsap\WNT7A, Hsap\WNT8A, Hsap\WNT16, Hsap\WNT5B, Hsap\WNT1, Hsap\WNT2" FBgn0003296 rub rubroad http://flybase.org/reports/FBgn0003296 - gene - - - rub - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "eye,wing,abdomen,male genitalia,tergite,wing vein" FBgn0033716 Den1 Deneddylase 1 http://flybase.org/reports/FBgn0033716 protein_coding_gene NEDD8-specific protease activity ; GO:0019784 | inferred from direct assay SUMO-specific protease activity ; GO:0016929 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 endopeptidase activity ; GO:0004175 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 positive regulation of apoptotic process ; GO:0043065 | inferred from genetic interaction with hid inferred from genetic interaction with rpr protein deneddylation ; GO:0000338 | inferred from direct assay protein desumoylation ; GO:0016926 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 "DEN1, Den1, CG8493" "IPR003653:Ulp1 protease family, C-terminal catalytic domain" CG8493 11-Aug-17 DroID_v2017_08 "Drer\senp8, Drer\senp3a, Drer\senp5, Drer\senp3b, Drer\eif4a1a, Drer\senp2" Scer\ULP1 "Cele\ulp-3, Cele\K04F10.7" Xtro\senp8 "Mmus\Senp3, Mmus\Senp5, Mmus\Senp8" "Hsap\SENP8, Hsap\SENP3, Hsap\SENP5" "viable,fertile" FBgn0032161 CG4594 - http://flybase.org/reports/FBgn0032161 protein_coding_gene enoyl-CoA hydratase activity ; GO:0004300 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000941570 CG4594 "IPR029045:ClpP/crotonase-like domain, IPR001753:Crotonase superfamily" CG4594 11-Aug-17 DroID_v2017_08 Drer\eci1 - - Xtro\eci1 Mmus\Eci1 Hsap\ECI1 "viable,fertile" FBgn0005005 Dented Dented http://flybase.org/reports/FBgn0005005 - gene - - - "Dented, De" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semidominant,viable,fertile" "adult thorax,wing" FBgn0260428 CG42523 - http://flybase.org/reports/FBgn0260428 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42523 - CG42523 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024543 l(3)L3051 lethal (3) L3051 http://flybase.org/reports/FBgn0024543 - gene - - - "l(3)L3051, Mgn095159" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028349 l(1)G0175 lethal (1) G0175 http://flybase.org/reports/FBgn0028349 gene - - - l(1)G0175 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "chaeta,wing" FBgn0039297 CG11852 - http://flybase.org/reports/FBgn0039297 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CT33073, CG11852" IPR010562:Haemolymph juvenile hormone binding CG11852 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030589 CG9519 - http://flybase.org/reports/FBgn0030589 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG9519, Dm GMCtheta1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9519 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0265705 CR44512 - http://flybase.org/reports/FBgn0265705 non_protein_coding_gene - - - CR44512 - CR44512 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003095 pl pleated http://flybase.org/reports/FBgn0003095 - gene - - - pl - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,cold sensitive" FBgn0031879 uif uninflatable http://flybase.org/reports/FBgn0031879 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" "negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with Dl inferred from genetic interaction with Ser inferred from genetic interaction with N regulation of tube architecture, open tracheal system ; GO:0035152 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype" apical plasma membrane ; GO:0016324 | inferred from direct assay "CT26172, poly-EGF, CG9138, uif, SP1070, Uif, sp1070, Poly-EGF" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000421:Coagulation factor 5/8 C-terminal domain, IPR000436:Sushi/SCR/CCP domain, IPR000742:EGF-like domain, IPR000859:CUB domain, IPR001881:EGF-like calcium-binding domain, IPR003410:HYR domain, IPR008979:Galactose-binding domain-like, IPR009030:Growth factor receptor cysteine-rich domain, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001368:TNFR/NGFR cysteine-rich region, IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR013783:Immunoglobulin-like fold, IPR011641:Tyrosine-protein kinase ephrin type A/B receptor-like, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG9138 11-Aug-17 DroID_v2017_08 "Drer\dlb, Drer\jag1b, Drer\notch1b, Drer\notch3, Drer\LOC100535882, Drer\si:ch73-173h19.3, Drer\col28a1a, Drer\svep1, Drer\scube1, Drer\adgrf6, Drer\fbln7, Drer\megf6b, Drer\zgc:158328, Drer\ltbp3, Drer\sned1, Drer\jag2a, Drer\col28a1a, Drer\crb2b, Drer\efemp1, Drer\crb2a, Drer\notch2, Drer\jag1a, Drer\matn3a, Drer\LOC100332841, Drer\dpy19l1l, Drer\scube3, Drer\fbln1, Drer\LOC562634, Drer\jag2b, Drer\adgrl4" - "Cele\crb-1, Cele\lin-12, Cele\F48E3.8, Cele\glp-1, Cele\clec-78" "Xtro\fbn1, Xtro\col14a1, Xtro\ltbp4, Xtro\matn4, Xtro\hgfac, Xtro\f12, Xtro\nell1, Xtro\svep1, Xtro\notch1, Xtro\notch2, Xtro\jag1, Xtro\crb2, Xtro\notch3" "Mmus\Crb1, Mmus\F12, Mmus\Fbn1, Mmus\Notch2, Mmus\Col28a1, Mmus\5330417C22Rik, Mmus\Vwde, Mmus\Col22a1, Mmus\Sned1, Mmus\Notch1, Mmus\Dlk2, Mmus\Egfl7, Mmus\Crb2, Mmus\Scube2, Mmus\Habp2, Mmus\Vwce, Mmus\Ltbp1, Mmus\Dll3, Mmus\Svep1, Mmus\Ltbp4, Mmus\Hgfac, Mmus\Fbln7, Mmus\Jag1, Mmus\Vwa1, Mmus\Jag2, Mmus\Scube3, Mmus\Notch3, Mmus\Cfc1, Mmus\Notch4, Mmus\Matn3, Mmus\Dll4, Mmus\Dlk1, Mmus\Tdgf1, Mmus\Hmcn2" "Hsap\VWA1, Hsap\SCUBE2, Hsap\EGFL7, Hsap\JAG1, Hsap\DLK1, Hsap\CFC1, Hsap\EYS, Hsap\LTBP1, Hsap\CRB2, Hsap\COL22A1, Hsap\COL14A1, Hsap\KIAA1324, Hsap\HABP2, Hsap\LOC100996717, Hsap\CFC1B, Hsap\CRB1, Hsap\NOTCH2NL, Hsap\SCUBE3, Hsap\F12, Hsap\NOTCH1, Hsap\DLL4, Hsap\SNED1, Hsap\VWCE, Hsap\NOTCH4, Hsap\SSPO, Hsap\HGFAC, Hsap\JAG2, Hsap\DLK2, Hsap\SVEP1, Hsap\FBLN7, Hsap\TDGF1, Hsap\NOTCH3, Hsap\DLL3, Hsap\MATN3, Hsap\NOTCH2" "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,small body,feeding behavior defective,partially lethal - majority die,visible" "embryonic/larval tracheal system,embryo,cephalopharyngeal skeleton,embryonic/larval dorsal trunk,taenidium,chaeta,supernumerary,trichogen cell,mesothoracic tergum,wing margin,wing vein,notal microchaeta,eye" FBgn0266001 CR44775 - http://flybase.org/reports/FBgn0266001 non_protein_coding_gene - - - CR44775 - CR44775 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040979 CG15285 - http://flybase.org/reports/FBgn0040979 protein_coding_gene - - - CG15285 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083246 EB4 EB4 http://flybase.org/reports/FBgn0083246 gene - - - EB4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266682 CR45172 - http://flybase.org/reports/FBgn0266682 non_protein_coding_gene - - - CR45172 - CR45172 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052823 Sdic3 Sperm-specific dynein intermediate chain 3 http://flybase.org/reports/FBgn0052823 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 "CG32823, Sdic3, Sdic:CG32823" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2" CG32823 11-Aug-17 DroID_v2017_08 "Drer\dync1i2b, Drer\dnai2a, Drer\LOC103908626, Drer\dync1i1, Drer\dnai1.1" Scer\PAC11 Cele\dyci-1 "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Dync1i1, Mmus\Dync1i2, Mmus\Wdr63" "Hsap\DYNC1I1, Hsap\WDR60, Hsap\DYNC1I2" FBgn0069923 CG41128 - http://flybase.org/reports/FBgn0069923 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000480690 "BcDNA:RH61753, CG41128, Minos1b, RH61753p" IPR007512:Protein of unknown function DUF543 CG41128 11-Aug-17 DroID_v2017_08 Drer\minos1 Scer\MIC10 Cele\F54A3.5 - Mmus\Minos1 "Hsap\MINOS1, Hsap\MINOS1-NBL1" FBgn0259755 ms(2)Fra-38 - http://flybase.org/reports/FBgn0259755 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - ms(2)Fra-38 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "Y chromosome loop,Nebenkern,spermatozoon" FBgn0037358 elm ethanol sensitive with low memory http://flybase.org/reports/FBgn0037358 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - plasma membrane ; GO:0005886 | inferred from direct assay "elm, CG2185" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG2185 11-Aug-17 DroID_v2017_08 "Drer\ppp3r1b, Drer\chp2, Drer\LOC100536377, Drer\ppp3r1a, Drer\chp1, Drer\tesca, Drer\tescb" Scer\CNB1 "Cele\chpf-1, Cele\pbo-1, Cele\chpf-2, Cele\T03F1.11" "Xtro\cib1, Xtro\chp1, Xtro\ppp3r1" "Mmus\Chp2, Mmus\Tescl, Mmus\Tesc, Mmus\Ppp3r2, Mmus\Cib1, Mmus\Ppp3r1, Mmus\Chp1, Mmus\Cib4" "Hsap\TESC, Hsap\PPP3R2, Hsap\CIB4, Hsap\PPP3R1, Hsap\CIB1, Hsap\CHP2, Hsap\CHP1" "chemical sensitive,memory defective,viable,fertile" FBgn0024532 l(3)L0580 lethal (3) L0580 http://flybase.org/reports/FBgn0024532 - gene - - - l(3)L0580 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033570 ND-B14 NADH dehydrogenase (ubiquinone) B14 subunit http://flybase.org/reports/FBgn0033570 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P56556 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P56556" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P56556 mitochondrion ; GO:0005739 | inferred from direct assay "BcDNA:RE25411, CG7712, NB4M, ND-B14" "IPR008011:Complex 1 LYR protein, IPR016488:NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6" CG7712 11-Aug-17 DroID_v2017_08 Drer\ndufa6 - Cele\nuo-3 Xtro\ndufa6 Mmus\Ndufa6 Hsap\NDUFA6 FBgn0259305 EP-731 - http://flybase.org/reports/FBgn0259305 gene - - - EP-731 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0278600 CG46270 - http://flybase.org/reports/FBgn0278600 protein_coding_gene - - - CG46270 - CG46270 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039909 ND-49 NADH dehydrogenase (ubiquinone) 49 kDa subunit http://flybase.org/reports/FBgn0039909 protein_coding_gene NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR001135 quinone binding ; GO:0048038 | inferred from electronic annotation with InterPro:IPR001135 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95299 "neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95299" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95299 mitochondrion ; GO:0005739 | inferred from direct assay "CG1970, CG 1970, NUCM, ND-49" "IPR001135:NADH-quinone oxidoreductase, subunit D, IPR014029:NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site, IPR029014:NiFe hydrogenase-like, IPR022885:NAD(P)H-quinone oxidoreductase subunit D/H" CG1970 11-Aug-17 DroID_v2017_08 "Drer\ndufs2, Drer\zgc:123301" - "Cele\gas-1, Cele\nduf-2.2" Xtro\ndufs2 Mmus\Ndufs2 Hsap\NDUFS2 "viable,visible" "chaeta,trichogen cell,adult heart,RU486 conditional" FBgn0267058 CR45502 - http://flybase.org/reports/FBgn0267058 non_protein_coding_gene - - - CR45502 - CR45502 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060868 l(3)S047212b lethal (3) S047212b http://flybase.org/reports/FBgn0060868 gene - - - "0472/12, l(3)S047212b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0036466 CG18581 - http://flybase.org/reports/FBgn0036466 protein_coding_gene - - - CG18581 - CG18581 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014069 Su(tor)3-8 Su(tor)3-8 http://flybase.org/reports/FBgn0014069 - gene - - - Su(tor)3-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0031040 CG14210 - http://flybase.org/reports/FBgn0031040 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BcDNA:RE23450, CG14210" "IPR005579:Cgr1-like, IPR026570:Coiled-coil domain-containing protein 86" CG14210 11-Aug-17 DroID_v2017_08 Drer\si:ch211-217k17.7 - Cele\Y40B1B.7 - Mmus\Ccdc86 Hsap\CCDC86 "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC19566 I -1.335384013 -1.846094513 0.148512678 -0.75149321 -0.006131984 -0.705589035 FBgn0037317 CG14667 - http://flybase.org/reports/FBgn0037317 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG14667 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG14667 11-Aug-17 DroID_v2017_08 Drer\bcl6ab - "Cele\lin-29, Cele\M03D4.4, Cele\Y55F3AM.14, Cele\blmp-1, Cele\klf-3" - "Mmus\E4f1, Mmus\Zfp810, Mmus\Repin1, Mmus\Rbak" "Hsap\ZNF8, Hsap\E4F1, Hsap\REPIN1, Hsap\ZNF560" viable FBgn0028073 l(3)S089004 l(3)S089004 http://flybase.org/reports/FBgn0028073 gene - - - "0893/02, 0890/04, l(3)S089302, l(3)S089004" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "oocyte nucleus,nurse cell & nucleusS089004S089004),follicle cell,nurse cell & nucleusS089004S089302)" FBgn0040210 iab-2PRE iab-2 Polycomb group response element http://flybase.org/reports/FBgn0040210 regulatory_region - - - iab-2PRE - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032924 Nbr Nibbler http://flybase.org/reports/FBgn0032924 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002562, InterPro:IPR012337 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing ; GO:0044748 | inferred from mutant phenotype" mature miRNA 3'-end processing ; GO:0044747 | inferred from mutant phenotype piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000341338 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000341338 intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay "CG9247, Nbr, nbr" "IPR002562:3'-5' exonuclease domain, IPR012337:Ribonuclease H-like domain" CG9247 11-Aug-17 DroID_v2017_08 Drer\exd3 - "Cele\Y57A10A.13, Cele\ZK1098.3, Cele\mut-7, Cele\W05H12.2" Xtro\exd3 - Hsap\EXD3 "viable,fertile,partially lethal - majority die,sterile,lethal,some die during pupal stage" FBgn0000831 fs(1)M13 female sterile (1) M13 http://flybase.org/reports/FBgn0000831 - gene - - - fs(1)M13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,female sterile,lethal,some die during embryonic stage" "egg,maternal effect,chorion | maternal effect,chorion" FBgn0038159 CG14369 - http://flybase.org/reports/FBgn0038159 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14369 - CG14369 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0004494 Ether-resistant Ether-resistant http://flybase.org/reports/FBgn0004494 - gene - - - "Eth, Ether-resistant" - - 11-Aug-17 DroID_v2017_08 - - - - - - "radiation sensitive,chemical resistant,dominant" FBgn0033473 CG12128 - http://flybase.org/reports/FBgn0033473 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12128 "IPR003750:Putative RNA methyltransferase, IPR012340:Nucleic acid-binding, OB-fold, IPR029028:Alpha/beta knot methyltransferases, IPR029026:tRNA (guanine-N1-)-methyltransferase, N-terminal" CG12128 11-Aug-17 DroID_v2017_08 Drer\zgc:101748 "Scer\YMR310C, Scer\YGR283C" Cele\B0361.6 Xtro\c9orf114 Mmus\Spout1 Hsap\SPOUT1 viable FBgn0029019 l(3)77CDe lethal (3) 77CDe http://flybase.org/reports/FBgn0029019 gene - - - l(3)77CDe - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0020621 Pkn Protein kinase N http://flybase.org/reports/FBgn0020621 "FBgn0004459, FBgn0010625, FBgn0015480, FBgn0028556, FBgn0033398, FBgn0033399" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017892 protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40792 inferred from physical interaction with UniProtKB:P48148 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40792 inferred from physical interaction with UniProtKB:P48148 inferred from physical interaction with UniProtKB:P48554 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity" dorsal closure ; GO:0007391 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay positive regulation of wound healing ; GO:0090303 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "PKN, CG2049, Dpkn, dPKN, l(2)45Ca, l(2)06736, DPKN, 3-2, PRK2, CT6660, CT6637, CG2055, v(2)rG232, Pk?3, Pk45C, Pkn, PKC-related, pkn, CG8" "IPR000008:C2 domain, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011072:HR1 rho-binding repeat, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal" CG2049 11-Aug-17 DroID_v2017_08 "Drer\tspy, Drer\pkn3, Drer\prkceb, Drer\seta, Drer\setb, Drer\prkcda, Drer\pkn2, Drer\sgk494b, Drer\zgc:153916, Drer\prkcq, Drer\prkcg, Drer\pkn1a, Drer\prkca, Drer\prkchb, Drer\prkcha, Drer\prkcbb, Drer\sgk494a, Drer\pkn1b, Drer\prkcea" Scer\PKC1 "Cele\spr-2, Cele\pkc-2, Cele\tpa-1, Cele\pkc-1, Cele\pkn-1, Cele\C56G2.5" "Xtro\LOC100493742, Xtro\set, Xtro\prkch, Xtro\tspyl2, Xtro\prkcb, Xtro\tnfrsf1a, Xtro\gpha2, Xtro\prkcg, Xtro\prkce, Xtro\prkcq, Xtro\pkn3, Xtro\prkcd, Xtro\pkn1, Xtro\pkn2" "Mmus\Tspyl4, Mmus\Set, Mmus\Prkcd, Mmus\Pkn2, Mmus\Prkcg, Mmus\Prkch, Mmus\Prkcb, Mmus\Prkcq, Mmus\Pkn1, Mmus\Tspyl3, Mmus\Prkca, Mmus\Tspyl1, Mmus\Tspyl5, Mmus\Pkn3, Mmus\BC030499, Mmus\Prkce" "Hsap\PKN1, Hsap\TSPYL6, Hsap\PKN3, Hsap\TSPYL4, Hsap\PRKCQ, Hsap\SGK494, Hsap\TSPYL5, Hsap\SETSIP, Hsap\PKN2, Hsap\SET, Hsap\PRKCH, Hsap\PRKCG, Hsap\PRKCA, Hsap\TSPYL1, Hsap\PRKCB, Hsap\PRKCD, Hsap\PRKCE" "wound healing defective,viable,lethal,polyphasic,recessive,visible,partially lethal - majority die,male sterile,planar polarity defective,lethal - all die before end of larval stage,some die during larval stage,wild-type,fertile" "dorsal closure embryo,germline clone,embryonic epidermis,dorsal,wing,wing margin bristle,wing vein,ectopic,wing hair,supernumerary,anterior wing margin,posterior wing margin,ommatidium" DRSC06809 I 0.666745006 -1.745623325 -0.118369712 -0.884659075 -0.673451338 -0.225938992 FBgn0060583 l(3)S094503 lethal (3) S094503 http://flybase.org/reports/FBgn0060583 gene - - - "0945/03, l(3)S094503" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0032382 Mal-B2 Maltase B2 http://flybase.org/reports/FBgn0032382 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "FBgn0032382, Mal-B2, CG14935, mal_B2, Drome_B2" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG14935 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-202g17.3, Drer\slc3a1, Drer\slc3a2a, Drer\zgc:158423, Drer\slc3a2b" "Scer\IMA1, Scer\IMA4, Scer\MAL32, Scer\IMA3, Scer\MAL12, Scer\IMA5, Scer\IMA2" "Cele\atgp-2, Cele\atgp-1" "Xtro\slc3a1, Xtro\slc3a2" "Mmus\Slc3a1, Mmus\Slc3a2" "Hsap\SLC3A2, Hsap\SLC3A1" viable FBgn0262243 mir-964 mir-964 stem loop http://flybase.org/reports/FBgn0262243 miRNA_gene - "regulation of feeding behavior ; GO:0060259 | inferred from genetic interaction with mir-959, mir-960, mir-961, mir-962, mir-963 immune response ; GO:0006955 | inferred from genetic interaction with mir-959, mir-960, mir-961, mir-962, mir-963" - "miR-964, dme-mir-964, mir-964, 964, CR42950, miR964, dme-miR-964-5p" - CR42950 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing vein" FBgn0044494 DTD45.7 DTD45.7 http://flybase.org/reports/FBgn0044494 gene - - - DTD45.7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260377 GSd230 - http://flybase.org/reports/FBgn0260377 gene - - - GSd230 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069302 X-97-26 X-97-26 http://flybase.org/reports/FBgn0069302 gene molecular_function ; GO:0003674 | no biological data available segment polarity determination ; GO:0007367 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-97-26 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,maternal effect,recessive,terminal phenotype,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,denticle belt" FBgn0066099 MCP-3.s MCP-3.s http://flybase.org/reports/FBgn0066099 gene - - - "MCP-3 s, MCP-3.s" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029778 RhoGAP5A Rho GTPase activating protein at 5A http://flybase.org/reports/FBgn0029778 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with RGD:620140 regulation of small GTPase mediated signal transduction ; GO:0051056 | inferred from electronic annotation with InterPro:IPR017356 imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from biological aspect of ancestor with PANTHER:PTN000571279 adherens junction maintenance ; GO:0034334 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with MGI:MGI:1915674 compound eye development ; GO:0048749 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with RGD:620140 regulation of MAPK cascade ; GO:0043408 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000571279 "CG3208, RhoGAP5A, RhoGAP" "IPR000198:Rho GTPase-activating protein domain, IPR000980:SH2 domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008936:Rho GTPase activation protein, IPR017356:Chimaerin, IPR020454:Diacylglycerol/phorbol-ester binding" CG3208 11-Aug-17 DroID_v2017_08 "Drer\arhgap15, Drer\myo9ab, Drer\arhgap29b, Drer\arhgap29a, Drer\si:ch211-253h3.1, Drer\LOC100005008, Drer\chn1, Drer\chn2, Drer\arhgap35, Drer\zgc:153345, Drer\myo9b, Drer\myo9aa, Drer\arhgap10" "Scer\BEM2, Scer\RGA1, Scer\RGA2, Scer\BEM3, Scer\ECM25, Scer\RGD1" "Cele\spv-1, Cele\chin-1, Cele\rga-5, Cele\T04C9.1, Cele\rga-1" "Xtro\myo9a, Xtro\arhgap26, Xtro\chn1, Xtro\abr, Xtro\chn2" "Mmus\Chn1, Mmus\Myo9a, Mmus\Hmha1, Mmus\Chn2, Mmus\Arhgap26, Mmus\Abr, Mmus\Arhgap35, Mmus\Arhgap29, Mmus\Arhgap15, Mmus\Myo9b, Mmus\Arhgap10, Mmus\Arhgap42" "Hsap\ABR, Hsap\ARHGAP35, Hsap\ARHGAP29, Hsap\CHN1, Hsap\ARHGAP42, Hsap\ARHGAP11B, Hsap\CHN2, Hsap\ARHGAP26, Hsap\MYO9B, Hsap\ARHGAP45, Hsap\ARHGAP15, Hsap\MYO9A, Hsap\ARHGAP10" "viable,fertile,planar polarity defective" FBgn0032295 CG12299 - http://flybase.org/reports/FBgn0032295 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG12299 "IPR013087:Zinc finger C2H2-type, IPR011989:Armadillo-like helical" CG12299 11-Aug-17 DroID_v2017_08 "Drer\zbtb49, Drer\zgc:175284, Drer\zbtb14, Drer\znf989, Drer\LOC100330452, Drer\si:ch73-40a17.4, Drer\zgc:174702, Drer\LOC100537317, Drer\si:ch211-198a12.6, Drer\LOC100329723, Drer\zgc:162962, Drer\zgc:113343, Drer\drl, Drer\LOC101884739, Drer\znf1160, Drer\si:ch211-155e24.3, Drer\LOC108179164, Drer\LOC560148, Drer\patz1, Drer\wu:fe17e08, Drer\zgc:113030, Drer\gtf3aa, Drer\LOC101884416, Drer\zgc:174623, Drer\im:7141269, Drer\LOC100538142, Drer\si:ch73-299h12.9, Drer\zgc:165514, Drer\znf131, Drer\zbtb34, Drer\LOC799968, Drer\mynn, Drer\zbtb2a, Drer\si:dkeyp-104f11.6, Drer\znf1168, Drer\si:dkey-261j4.5, Drer\LOC103909987, Drer\znf319, Drer\LOC103911016, Drer\LOC101883594, Drer\zgc:171673, Drer\si:dkey-34m19.3, Drer\zbtb48, Drer\LOC101883230, Drer\zbtb17, Drer\zgc:112998, Drer\LOC100330167, Drer\znf366, Drer\LOC100333031, Drer\zbtb24, Drer\zgc:174703, Drer\si:ch211-276c2.4, Drer\zgc:113102, Drer\si:ch211-222k6.2, Drer\zgc:101130, Drer\si:ch211-241b2.4, Drer\zbtb43, Drer\si:rp71-1h20.5, Drer\si:dkey-261j4.3, Drer\si:dkey-262g12.3, Drer\si:dkey-261j4.4, Drer\znf1162, Drer\LOC100535385, Drer\hic1l" "Scer\PZF1, Scer\AZF1" "Cele\pag-3, Cele\che-1, Cele\ces-1, Cele\Y55F3AM.14, Cele\scrt-1, Cele\Y56A3A.28, Cele\lin-29, Cele\egl-43, Cele\ZK686.5, Cele\hinf-1, Cele\fezf-1, Cele\pzf-1, Cele\F57C9.4" "Xtro\znf684, Xtro\znf585b, Xtro\zbtb47, Xtro\rbfox1, Xtro\gtf3a, Xtro\znf350" "Mmus\Zbtb38, Mmus\Zbtb37, Mmus\Zfp516, Mmus\Zbtb18, Mmus\Zfp26, Mmus\Zfp637, Mmus\Zbtb49, Mmus\Zfp768, Mmus\Zbtb17, Mmus\Zfp37, Mmus\Zfp382, Mmus\Zbtb6, Mmus\Zbtb44, Mmus\Zbtb34, Mmus\Zfp39, Mmus\Zfp710, Mmus\Zfp131, Mmus\Zfp853, Mmus\Zkscan6, Mmus\Zfp521, Mmus\Zbtb14, Mmus\Zfp526, Mmus\Zfp358, Mmus\Zbtb24, Mmus\Zfp366, Mmus\Zbtb48, Mmus\Zfp870, Mmus\Zbtb2, Mmus\Zfp341, Mmus\Gtf3a" "Hsap\ZNF143, Hsap\GTF3A, Hsap\ZNF787, Hsap\ZNF853, Hsap\ZBTB2, Hsap\ZBTB18, Hsap\ZNF341, Hsap\ZNF710, Hsap\ZNF296, Hsap\SALL2, Hsap\ZNF516, Hsap\ZBTB6, Hsap\ZNF850, Hsap\ZNF408, Hsap\ZBTB25, Hsap\ZBTB43, Hsap\ZNF366, Hsap\ZBTB37, Hsap\ZNF224, Hsap\ZBTB38, Hsap\ZNF521, Hsap\ZNF32, Hsap\MYNN, Hsap\ZNF358, Hsap\ZBTB17, Hsap\ZNF219, Hsap\ZBTB14, Hsap\ZNF473, Hsap\ZNF131" DRSC23611 EK 0.574095059 0.093929516 3.669384071 -2.502723193 0.237569401 2.819134157 FBgn0050360 Mal-A6 Maltase A6 http://flybase.org/reports/FBgn0050360 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "CG8689, Mal-A6, CG30360, mal_A6, Drome_A6" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG30360 11-Aug-17 DroID_v2017_08 "Drer\zgc:158423, Drer\slc3a1, Drer\si:dkey-202g17.3, Drer\slc3a2b, Drer\slc3a2a" "Scer\MAL12, Scer\IMA5, Scer\IMA1, Scer\MAL32, Scer\IMA2, Scer\IMA3, Scer\IMA4" "Cele\atgp-2, Cele\atgp-1" "Xtro\slc3a2, Xtro\slc3a1" "Mmus\Slc3a1, Mmus\Slc3a2" "Hsap\SLC3A1, Hsap\SLC3A2" viable FBgn0267913 CR46194 - http://flybase.org/reports/FBgn0267913 non_protein_coding_gene - - - CR46194 - CR46194 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259951 Sfp24Ba Seminal fluid protein 24Ba http://flybase.org/reports/FBgn0259951 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 peptidase inhibitor activity ; GO:0030414 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "Sfp24Ba, CG42461, SFP24BA" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG42461 11-Aug-17 DroID_v2017_08 "Drer\tfpi2, Drer\ambp" - - - "Mmus\Ambp, Mmus\Spint4, Mmus\Tfpi" "Hsap\TFPI, Hsap\AMBP, Hsap\SPINT4" FBgn0017425 anon-68Ec anon-68Ec http://flybase.org/reports/FBgn0017425 - gene - - - "T3, anon-68Ec" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000127 Ars-region5 Autonomous replicating sequence region 5 http://flybase.org/reports/FBgn0000127 - region - - - "BgHS500, Ars-region5, Ars5" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259868 Su(Ste):CR42437 Su(Ste):CR42437 http://flybase.org/reports/FBgn0259868 non_protein_coding_gene - - - "Su(Ste):CR42437, CR42437" - CR42437 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036761 MED19 Mediator complex subunit 19 http://flybase.org/reports/FBgn0036761 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with UniProtKB:Q9VEC1 transcription factor binding ; GO:0008134 | inferred from physical interaction with abd-A inferred from physical interaction with Dfd inferred from physical interaction with Ubx transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with UniProtKB:Q9VEC1 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype mediator complex ; GO:0016592 | inferred from sequence or structural similarity with UniProtKB:Q9VEC1 mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN001096178 "CG5546, MED19, Med19" "IPR019403:Mediator complex, subunit Med19, metazoa, IPR015943:WD40/YVTN repeat-like-containing domain" CG5546 11-Aug-17 DroID_v2017_08 "Drer\med19b, Drer\med19a" - Cele\mdt-19 Xtro\med19 Mmus\Med19 Hsap\MED19 "lethal - all die during pupal stage,lethal,visible,lethal - all die during embryonic stage,germline clone,maternal effect,cell lethalcell lethal,somatic clone,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" "anterior pupal spiracle,maxillary palpus,dorsal pedicellar sensillum campaniformium,somatic clone - Minute background" DRSC10516 IK -1.047498301 2.637731814 0.46131678 0.636877539 3.906288687 2.161548203 FBgn0002459 l(3)SG12 lethal (3) SG12 http://flybase.org/reports/FBgn0002459 - gene - - - "l(3)J151, l(3)SG12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0067353 l(3)95EFc lethal (3) 95EFc http://flybase.org/reports/FBgn0067353 gene - - - l(3)95EFc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267263 CR45699 - http://flybase.org/reports/FBgn0267263 non_protein_coding_gene - - - CR45699 - CR45699 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037468 CG1943 - http://flybase.org/reports/FBgn0037468 protein_coding_gene - "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - CG1943 IPR033335:Microtubule-associated protein Jupiter/Hematological and neurological expressed 1 CG1943 11-Aug-17 DroID_v2017_08 "Drer\hn1a, Drer\hn1l, Drer\hn1b" - - - "Mmus\Hn1, Mmus\Hn1l" "Hsap\HN1L, Hsap\HN1" "lethal,recessive,viable" FBgn0024214 l(3)E22 lethal (3) E22 http://flybase.org/reports/FBgn0024214 - gene - - - l(3)E22 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266738 CR45211 - http://flybase.org/reports/FBgn0266738 non_protein_coding_gene - - - CR45211 - CR45211 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028986 Spn38F Serpin 38F http://flybase.org/reports/FBgn0028986 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from sequence or structural similarity multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype negative regulation of proteolysis ; GO:0045861 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG9334, sp3, Spn3, Sp3, Spn38F" "IPR000215:Serpin family, IPR023796:Serpin domain" CG9334 11-Aug-17 DroID_v2017_08 "Drer\serpina1l, Drer\serpine1, Drer\serpina10a, Drer\serpine2, Drer\serpinb1, Drer\serpinc1, Drer\serpinh2, Drer\serpinb1l2, Drer\serpinh1b, Drer\serpina7, Drer\si:ch1073-416d2.3, Drer\serpinh1a, Drer\serpinb1l1, Drer\serpine3, Drer\zgc:174259, Drer\serpinb14, Drer\serpind1, Drer\serpini1, Drer\si:ch211-186e20.7, Drer\zgc:173729, Drer\serpinb1l4, Drer\serpinb1l3" - "Cele\srp-2, Cele\srp-3, Cele\srp-7, Cele\srp-6, Cele\srp-1, Cele\srp-8" "Xtro\serpini2, Xtro\serpine2, Xtro\serpina1, Xtro\serpinb1, Xtro\serpinb6, Xtro\serpinc1, Xtro\serpina10, Xtro\serpinb11, Xtro\serpini1, Xtro\serpina3k, Xtro\serpinb5, Xtro\serpinb4, Xtro\serpina3, Xtro\serpine1, Xtro\serpind1, Xtro\serpina3m" "Mmus\Serpinb3d, Mmus\Gm11397, Mmus\Serpinb3b, Mmus\Serpina3g, Mmus\Serpinh1, Mmus\Serpinb9, Mmus\Serpinb1b, Mmus\Serpina1a, Mmus\Serpinb6e, Mmus\Serpina1d, Mmus\Serpina3n, Mmus\Serpina7, Mmus\Serpinb6b, Mmus\Serpina16, Mmus\Serpina3c, Mmus\Serpinb10, Mmus\Serpine1, Mmus\Serping1, Mmus\Serpina3a, Mmus\Serpina3i, Mmus\Serpina9, Mmus\Serpinb9f, Mmus\Serpinc1, Mmus\Serpina1e, Mmus\Serpinb8, Mmus\Serpina3f, Mmus\Serpinb6d, Mmus\Serpinb5, Mmus\Serpini1, Mmus\Serpinb3c, Mmus\Serpinb9d, Mmus\Serpinb9e, Mmus\Serpinb9g, Mmus\Serpinb1a, Mmus\Serpine2, Mmus\Serpina12, Mmus\Serpina10, Mmus\Serpine3, Mmus\Serpinb11, Mmus\Serpinb9b, Mmus\Serpina3k, Mmus\Serpina5, Mmus\Serpinb6a, Mmus\Serpina11, Mmus\Serpind1, Mmus\Serpina1c, Mmus\Serpinb13, Mmus\Serpinb2, Mmus\Serpinb6c, Mmus\Serpinb1c, Mmus\Serpinb3a, Mmus\Serpinb9c, Mmus\Serpina6, Mmus\Serpinb12, Mmus\Serpina3j, Mmus\Serpini2, Mmus\Serpinb7" "Hsap\SERPINI2, Hsap\SERPINB5, Hsap\SERPINI1, Hsap\SERPINB7, Hsap\SERPINB2, Hsap\SERPINA7, Hsap\SERPINC1, Hsap\SERPINA3, Hsap\SERPINA10, Hsap\SERPINA12, Hsap\SERPINE3, Hsap\SERPINE2, Hsap\SERPINE1, Hsap\SERPINA1, Hsap\SERPIND1, Hsap\SERPINB8, Hsap\SERPINH1, Hsap\SERPING1, Hsap\HMSD, Hsap\SERPINB1, Hsap\SERPINB11, Hsap\SERPINB9, Hsap\SERPINB12, Hsap\SERPINB6, Hsap\SERPINB3, Hsap\SERPINA5, Hsap\SERPINB10, Hsap\SERPINA6, Hsap\SERPINA9, Hsap\SERPINB13, Hsap\SERPINB4, Hsap\SERPINA11, Hsap\SERPINA4" viable FBgn0027376 rha rha http://flybase.org/reports/FBgn0027376 FBgn0044579 protein_coding_gene - - - "RADHA, CG11908, anon-WO0140519.50, rha" IPR022136:Domain of unknown function DUF3668 CG11908 11-Aug-17 DroID_v2017_08 - - - - Mmus\Cep120 - "viable,fertile" FBgn0053409 5SrRNA:CR33409 5SrRNA:CR33409 http://flybase.org/reports/FBgn0053409 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33409, 5SrRNA:CR33409" - CR33409 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065365 l(2)SH1722 lethal (2) SH1722 http://flybase.org/reports/FBgn0065365 gene - - - "l(2)SH1722, l(2)SH2 1722" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261554 CG42672 - http://flybase.org/reports/FBgn0261554 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42672, CG30386, CG15665, CG10074, CG30387" "IPR002110:Ankyrin repeat, IPR011646:KAP family P-loop domain, IPR020683:Ankyrin repeat-containing domain, IPR013761:Sterile alpha motif/pointed domain" CG42672 11-Aug-17 DroID_v2017_08 "Drer\kidins220a, Drer\si:dkey-86e18.2, Drer\ankra2, Drer\si:dkey-145p14.5, Drer\nkpd1, Drer\rfxank, Drer\kidins220b, Drer\invs, Drer\ankrd22" - "Cele\R11A8.7, Cele\T28D6.4, Cele\kdin-1, Cele\C45B2.6" "Xtro\rfxank, Xtro\kidins220, Xtro\ankrd50, Xtro\ankra2, Xtro\nkpd1" "Mmus\Invs, Mmus\Ankrd50, Mmus\Nkpd1, Mmus\Rnasel, Mmus\Ankra2, Mmus\Ankrd22, Mmus\Kidins220, Mmus\Rfxank" "Hsap\INVS, Hsap\ANKRA2, Hsap\RFXANK, Hsap\NKPD1, Hsap\ANKRD22, Hsap\KIDINS220, Hsap\ANKRD50, Hsap\RNASEL" DRSC04256 IEK -1.378880952 -6.427472136 -1.688549914 -6.668325594 -5.98001899 -5.378363508 FBgn0263380 CR43432 - http://flybase.org/reports/FBgn0263380 non_protein_coding_gene - - - "CR43432, chr3L:14942577..14942904" - CR43432 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010729 l(3)00835 lethal (3) 00835 http://flybase.org/reports/FBgn0010729 - gene - - - l(3)00835 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011599 gui guillotined http://flybase.org/reports/FBgn0011599 - gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gui - - 11-Aug-17 DroID_v2017_08 - - - - - - "chordotonal organ & axon | lateral,RP1 motor neuron,RP3 motor neuron" FBgn0002462 l(3)SG15 lethal (3) SG15 http://flybase.org/reports/FBgn0002462 - gene - - - l(3)SG15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" imaginal disc FBgn0010551 Phb2 Prohibitin 2 http://flybase.org/reports/FBgn0010551 "FBgn0034395, FBgn0062207, FBgn0067804" protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000163 mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG15081, anon-WO02079478.4, anon-WO0118547.157, l(2)03709, l (2) 03709, Phb2, phb2" "IPR000163:Prohibitin, IPR001107:Band 7 domain" CG15081 11-Aug-17 DroID_v2017_08 "Drer\phb2b, Drer\phb, Drer\phb2a" Scer\PHB2 "Cele\phb-2, Cele\phb-1" "Xtro\phb2, Xtro\phb" "Mmus\Phb2, Mmus\Phb" "Hsap\PHB2, Hsap\PHB" "lethal,partially lethal - majority die,visible,recessive" mesothoracic tergum DRSC06512 IE -2.195367449 -2.532544615 -2.073026724 -1.834112871 0.215769438 -0.378994529 FBgn0028936 NimB5 Nimrod B5 http://flybase.org/reports/FBgn0028936 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with UniProtKB:Q1HAY7 extracellular region ; GO:0005576 | inferred from sequence model "CG16873, BG:DS00180.9, NimB5, nimB5" "IPR013032:EGF-like, conserved site, IPR009030:Growth factor receptor cysteine-rich domain, IPR000742:EGF-like domain" CG16873 11-Aug-17 DroID_v2017_08 "Drer\dkk2, Drer\tnfaip6, Drer\zgc:158328, Drer\scarf1, Drer\megf10, Drer\megf11, Drer\pear1, Drer\megf6b, Drer\ccbe1, Drer\megf6a, Drer\esm1, Drer\dkk1a" - "Cele\Y34B4A.5, Cele\ZK1193.3, Cele\R09H10.5, Cele\B0393.5" "Xtro\megf11, Xtro\tnfaip6, Xtro\stab2" "Mmus\Dkk2, Mmus\Egfem1, Mmus\Dkk3, Mmus\Esm1, Mmus\Scarf1, Mmus\Stab1, Mmus\Tnfaip6, Mmus\Megf11, Mmus\Pear1, Mmus\Megf6, Mmus\Megf10" "Hsap\MEGF10, Hsap\PEAR1, Hsap\MEGF11, Hsap\TNFAIP6, Hsap\DKK2, Hsap\MEGF6, Hsap\SCARF2, Hsap\SCARF1" viable FBgn0062270 huc29DE hydroxyurea- and (or) caffeine-sensitive 29DE http://flybase.org/reports/FBgn0062270 gene - - - "huc, huc29DE, huc[29DE], Huc-29DE" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "eye,somatic clone,drug conditional,ommatidium,eye photoreceptor cell" FBgn0004757 l(3)89Bj lethal (3) 89Bj http://flybase.org/reports/FBgn0004757 - gene - - - l(3)89Bj - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267602 CR45940 - http://flybase.org/reports/FBgn0267602 non_protein_coding_gene - - - CR45940 - CR45940 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011794 l(3)j6C3 lethal (3) j6C3 http://flybase.org/reports/FBgn0011794 - gene - - - l(3)j6C3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003871 ttr tetrapter http://flybase.org/reports/FBgn0003871 - gene - - - ttr - - 11-Aug-17 DroID_v2017_08 - - - - - - haltere FBgn0032058 CG9289 - http://flybase.org/reports/FBgn0032058 protein_coding_gene - - - "CT26467, CG9289" "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG9289 11-Aug-17 DroID_v2017_08 "Drer\cell, Drer\nlgn4a, Drer\nlgn2a, Drer\nlgn3b, Drer\nlgn3a, Drer\ces3, Drer\si:ch211-93f2.1, Drer\nlgn1, Drer\nlgn4b, Drer\nlgn2b, Drer\cel.1, Drer\ces2" - "Cele\K11G9.1, Cele\R173.3, Cele\F15A8.6, Cele\B0238.7, Cele\Y71H2AM.13, Cele\T07H6.1, Cele\F07C4.12, Cele\K11G9.3, Cele\ges-1, Cele\K11G9.2, Cele\F56C11.6, Cele\K07C11.4, Cele\F13H6.3, Cele\T28C12.4" "Xtro\nlgn3, Xtro\cel, Xtro\nlgn2, Xtro\ces2, Xtro\LOC100494782, Xtro\nlgn4x, Xtro\ces3" "Mmus\Ces2c, Mmus\Ces3a, Mmus\Ces1g, Mmus\Nlgn2, Mmus\Ces2h, Mmus\Cel, Mmus\Ces1c, Mmus\Ces2b, Mmus\Nlgn3, Mmus\Ces4a, Mmus\Ces1d, Mmus\Ces1e, Mmus\Ces2f, Mmus\Nlgn1, Mmus\Ces2g, Mmus\Ces2e, Mmus\Ces3b, Mmus\Ces1b, Mmus\Ces2a, Mmus\Ces5a, Mmus\Ces1h, Mmus\Ces1f" "Hsap\CES3, Hsap\CEL, Hsap\NLGN3, Hsap\CES2, Hsap\NLGN4X, Hsap\NLGN1, Hsap\NLGN4Y, Hsap\CES4A, Hsap\NLGN2, Hsap\CES5A, Hsap\CES1" "viable,fertile" FBgn0034063 CG8389 - http://flybase.org/reports/FBgn0034063 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG8389 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8389 11-Aug-17 DroID_v2017_08 "Drer\slc16a12b, Drer\slc16a7, Drer\slc16a9a, Drer\slc16a9b, Drer\slc16a6a, Drer\slc16a12a, Drer\slc16a5a, Drer\si:ch211-234h8.7, Drer\slc16a1a, Drer\slc16a5b" "Scer\MCH4, Scer\MCH2, Scer\ESBP6, Scer\ATG22, Scer\MCH5" "Cele\mct-6, Cele\slcf-1, Cele\mct-3" "Xtro\slc16a3, Xtro\slc16a9, Xtro\slc16a7, Xtro\slc16a2, Xtro\slc16a12, Xtro\slc16a5" "Mmus\Slc16a6, Mmus\Slc16a11, Mmus\Slc16a2, Mmus\Slc16a5, Mmus\Slc16a9, Mmus\Slc16a12, Mmus\Slc16a13, Mmus\Slc16a14" "Hsap\SLC16A8, Hsap\SLC16A2, Hsap\SLC16A5, Hsap\SLC16A10, Hsap\SLC16A11, Hsap\SLC16A1, Hsap\SLC16A6, Hsap\SLC16A14, Hsap\SLC16A12, Hsap\SLC16A9" "viable,fertile" DRSC07158 IEK 2.121757431 0.614778668 1.640739893 2.612725654 2.862972285 -0.622564141 FBgn0266628 CR45135 - http://flybase.org/reports/FBgn0266628 non_protein_coding_gene - - - CR45135 - CR45135 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267683 CR46019 - http://flybase.org/reports/FBgn0267683 non_protein_coding_gene - - - CR46019 - CR46019 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033216 CG1946 - http://flybase.org/reports/FBgn0033216 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR007130" - - CG1946 IPR007130:Diacylglycerol acyltransferase CG1946 11-Aug-17 DroID_v2017_08 "Drer\mogat3a, Drer\dgat2, Drer\mogat3b, Drer\mogat2" Scer\DGA1 "Cele\dgat-2, Cele\Y53G8B.2, Cele\dgtr-1, Cele\K07B1.4" "Xtro\mogat1, Xtro\mogat2.1, Xtro\awat1, Xtro\dgat2, Xtro\dgat2l6, Xtro\mogat3" "Mmus\Awat2, Mmus\Mogat2, Mmus\Mogat1, Mmus\Dgat2l6, Mmus\Awat1, Mmus\Dgat2" "Hsap\DGAT2, Hsap\AWAT1, Hsap\AWAT2, Hsap\MOGAT1, Hsap\MOGAT2, Hsap\MOGAT3, Hsap\DGAT2L6" viable FBgn0011014 l(3)s1922 lethal (3) s1922 http://flybase.org/reports/FBgn0011014 - gene - - - l(3)s1922 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000369 cr-b cream b http://flybase.org/reports/FBgn0000369 - gene - - - cr-b - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0259573 B0176 - http://flybase.org/reports/FBgn0259573 gene - - - B0176 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing,wing vein,chaeta,ectopic" FBgn0040111 l(3)tk11 lethal (3) tk11 http://flybase.org/reports/FBgn0040111 gene - - - "tk11, l(3)tk11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037572 CG11698 - http://flybase.org/reports/FBgn0037572 protein_coding_gene molecular_function ; GO:0003674 | no biological data available developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 cellular_component ; GO:0005575 | no biological data available CG11698 IPR007999:Protein of unknown function DUF745 CG11698 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259364 C596 - http://flybase.org/reports/FBgn0259364 gene - - - C596 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0262338 mir-2499 mir-2499 stem loop http://flybase.org/reports/FBgn0262338 miRNA_gene - - - "mir-2499, CR43045, dme-mir-2499, miR-2499" - CR43045 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259456 EP-820 - http://flybase.org/reports/FBgn0259456 gene - - - EP-820 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0052319 Naa30B N(alpha)-acetyltransferase 30 B http://flybase.org/reports/FBgn0052319 protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from biological aspect of ancestor with PANTHER:PTN000558065 N-terminal protein amino acid acetylation ; GO:0006474 | inferred from biological aspect of ancestor with PANTHER:PTN000558065 NatC complex ; GO:0031417 | inferred from biological aspect of ancestor with PANTHER:PTN000558222 "CG12083, Naa30, Naa30B, CG32319" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG32319 11-Aug-17 DroID_v2017_08 Drer\naa30 Scer\MAK3 Cele\natc-2 "Xtro\cml, Xtro\naa30" "Mmus\Naa30, Mmus\Nat8f7, Mmus\Nat8f6, Mmus\Nat8f3, Mmus\Nat8f5" "Hsap\NAA30, Hsap\NAT8, Hsap\SAT2" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0026657 l(2)18E4 lethal (2) 18E4 http://flybase.org/reports/FBgn0026657 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)18E4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0263075 l(3)10477 lethal (3) 10477 http://flybase.org/reports/FBgn0263075 gene - - - l(3)10477 - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority die FBgn0260397 Su(var)3-3 Suppressor of variegation 3-3 http://flybase.org/reports/FBgn0260397 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR017366 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753 histone demethylase activity (H3-K4 specific) ; GO:0032453 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q59E36" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753 oogenesis ; GO:0048477 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype histone H3-K4 demethylation ; GO:0034720 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype positive regulation of methylation-dependent chromatin silencing ; GO:0090309 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype heterochromatin organization ; GO:0070828 | inferred from mutant phenotype" transcriptional repressor complex ; GO:0017053 | inferred from physical interaction with HDAC1 inferred from physical interaction with CoRest nucleus ; GO:0005634 | inferred from direct assay "SU(VAR)3-3, CG17149, Su(var)3-3, Suvar(3)3, lsd1, LSD1, Su-var(3)3, Hdm, Dmel\LSD1, Dmel/HDM, Dmel/LSD1, Lsd1, dLsd1, dLSD1" "IPR002937:Amine oxidase, IPR007526:SWIRM domain, IPR017366:Histone lysine-specific demethylase, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR023753:FAD/NAD(P)-binding domain" CG17149 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-275b16.2, Drer\smox, Drer\kdm1a, Drer\si:ch211-127i16.2, Drer\mao, Drer\si:dkey-40g16.6" Scer\FMS1 "Cele\amx-3, Cele\hpo-15, Cele\lsd-1, Cele\spr-5, Cele\amx-2, Cele\amx-1" "Xtro\kdm1a, Xtro\maob, Xtro\kdm1b, Xtro\smox, Xtro\maoa" "Mmus\Maoa, Mmus\Smox, Mmus\Paox, Mmus\Maob, Mmus\Il4i1, Mmus\4930438A08Rik, Mmus\Lao1, Mmus\Kdm1b, Mmus\Kdm1a" "Hsap\IL4I1, Hsap\MAOA, Hsap\KDM1B, Hsap\PAOX, Hsap\SMOX, Hsap\MAOB, Hsap\KDM1A" DRSC10250 K 0.033335981 -0.026503002 0.65577557 0.80469299 -1.729937607 -0.311198969 FBgn0005549 l(3)73Bd lethal (3) 73Bd http://flybase.org/reports/FBgn0005549 - gene - - - l(3)73Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001594 l(1)carot11 lethal (1) carot11 http://flybase.org/reports/FBgn0001594 - gene - - - l(1)carot11 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0033252 CG12769 - http://flybase.org/reports/FBgn0033252 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG12769 IPR013087:Zinc finger C2H2-type CG12769 11-Aug-17 DroID_v2017_08 "Drer\zgc:113135, Drer\LOC100538201, Drer\znf1078, Drer\LOC101882607, Drer\znf687a, Drer\si:dkey-166n8.9, Drer\znf1053, Drer\znf644b, Drer\LOC103910994, Drer\znf1167, Drer\si:dkeyp-35e5.10, Drer\si:ch211-212k5.4, Drer\znf408, Drer\znf995, Drer\LOC100537431, Drer\znf1043, Drer\znf507, Drer\zgc:174704, Drer\zbtb17, Drer\LOC100149007, Drer\si:dkey-237m9.1, Drer\LOC100537450, Drer\LOC100333857, Drer\prdm4, Drer\znf1159, Drer\zgc:173713, Drer\si:dkey-7i4.5, Drer\znf1171, Drer\znf687b, Drer\gb:am422109, Drer\LOC108184006, Drer\si:dkeyp-104f11.6, Drer\zgc:173705, Drer\LOC100536110, Drer\si:dkey-20i20.2, Drer\LOC569391, Drer\LOC101885678, Drer\LOC100150619, Drer\znf569l, Drer\si:dkey-1b17.5, Drer\LOC101882721, Drer\zgc:174696, Drer\LOC108179202, Drer\zgc:174315, Drer\LOC100149645, Drer\si:dkey-30f3.2, Drer\zbtb39, Drer\si:dkey-217d24.6, Drer\si:ch211-194b1.1, Drer\zgc:174703, Drer\si:ch211-255f4.1, Drer\zgc:173624, Drer\LOC100537891, Drer\LOC108183430, Drer\LOC100534765, Drer\LOC101882787, Drer\LOC100333583, Drer\znf1173, Drer\LOC100536900, Drer\znf644a, Drer\znf1147, Drer\zgc:173716, Drer\znf1073, Drer\si:ch211-223a21.4, Drer\si:ch211-162i8.2, Drer\znf1072, Drer\zgc:174314, Drer\znf1041, Drer\LOC100329723, Drer\znf407, Drer\LOC101883642, Drer\znf1070, Drer\si:ch211-255f4.3, Drer\znf319, Drer\znf1177, Drer\si:dkey-262g12.7, Drer\si:ch73-266f23.3, Drer\si:dkeyp-53d3.5, Drer\znf1181, Drer\znf592, Drer\znf1059, Drer\znf1079, Drer\zbtb41, Drer\prdm2a, Drer\LOC100535113, Drer\si:dkeyp-35e5.9, Drer\si:ch211-226o13.2, Drer\LOC100536312, Drer\LOC100537572, Drer\LOC100537066, Drer\zgc:173714, Drer\prdm2b, Drer\mynn, Drer\LOC103910931, Drer\LOC108183429, Drer\LOC100332458, Drer\hnrnpa0l, Drer\LOC100534892, Drer\znf1077, Drer\LOC101885193, Drer\LOC100536649, Drer\zgc:162948, Drer\znf1069, Drer\znf1068, Drer\LOC100537352, Drer\LOC108182424, Drer\znf1040" Scer\MET31 "Cele\ztf-16, Cele\ehn-3, Cele\sdz-12, Cele\C46E10.9, Cele\F26F4.8" "Xtro\ikzf2, Xtro\trps1" "Mmus\Zbtb17, Mmus\Zfp768, Mmus\Zfp942, Mmus\Zfp97, Mmus\Zkscan7, Mmus\Zfp985, Mmus\Zfp870, Mmus\Zfp979, Mmus\Zfp407, Mmus\Zfp319, Mmus\Zfp94, Mmus\Zfp644, Mmus\Zfp995, Mmus\Rsl1, Mmus\Zfp597, Mmus\Zfp991, Mmus\Zfp114, Mmus\Zfp784, Mmus\Zfp872, Mmus\Gm10778, Mmus\4930522L14Rik, Mmus\Zfp120, Mmus\Ikzf2, Mmus\Zbtb41, Mmus\Zfp980, Mmus\Zfp429, Mmus\Zfp943, Mmus\Zfp871, Mmus\Zfp746, Mmus\Prdm4, Mmus\Zfp445, Mmus\Zfp408, Mmus\Prdm2, Mmus\Zfp866, Mmus\Mynn, Mmus\Zfp868, Mmus\Zfp534, Mmus\Zfp777, Mmus\Zfp758, Mmus\Zfp987, Mmus\Zfp93, Mmus\Zfp592, Mmus\Rex2, Mmus\Zfp981, Mmus\Gm20939, Mmus\Zfp108, Mmus\Zfp57, Mmus\Zfp992, Mmus\Zfp687, Mmus\Zfp472, Mmus\AU041133, Mmus\Zfp867, Mmus\Zfp467, Mmus\Zfp951, Mmus\Zfp947, Mmus\Zfp61, Mmus\Zfp697, Mmus\Zfp462, Mmus\Zfp820, Mmus\Zfp982, Mmus\Zfp984, Mmus\Zfp563, Mmus\Zfp944, Mmus\Zfp960, Mmus\Zfp287, Mmus\Zfp932, Mmus\Gzf1, Mmus\Trps1, Mmus\Zfp507, Mmus\Zfp646, Mmus\Zfp426, Mmus\Fiz1, Mmus\Zfp398, Mmus\Zfp946, Mmus\Zfp109, Mmus\Zbtb39, Mmus\Gm4767, Mmus\Zfp786" "Hsap\ZNF230, Hsap\ZNF687, Hsap\ZNF214, Hsap\ZNF462, Hsap\MYNN, Hsap\ZNF697, Hsap\ZNF17, Hsap\ZNF319, Hsap\ZNF333, Hsap\ZNF155, Hsap\ZNF416, Hsap\ZNF768, Hsap\ZNF34, Hsap\ZNF527, Hsap\GZF1, Hsap\ZNF806, Hsap\ZNF784, Hsap\ZNF587, Hsap\ZNF136, Hsap\ZNF707, Hsap\IKZF1, Hsap\ZNF222, Hsap\ZNF776, Hsap\ZNF646, Hsap\ZNF507, Hsap\ZNF530, Hsap\ZNF445, Hsap\ZNF592, Hsap\ZNF670, Hsap\ZNF774, Hsap\ZNF777, Hsap\ZNF407, Hsap\ZNF597, Hsap\PRDM4, Hsap\PRDM2, Hsap\ZNF223, Hsap\ZNF398, Hsap\ZNF417, Hsap\ZKSCAN7, Hsap\IKZF4, Hsap\ZNF408, Hsap\ZNF467, Hsap\ZNF285, Hsap\ZNF287, Hsap\ZBTB41, Hsap\IKZF2, Hsap\ZNF547, Hsap\ZNF786, Hsap\ZNF852, Hsap\ZNF746, Hsap\ZBTB39, Hsap\ZNF426, Hsap\ZFP57, Hsap\ZNF644, Hsap\TRPS1, Hsap\IKZF3, Hsap\ZBTB17" viable FBgn0031033 CG14219 - http://flybase.org/reports/FBgn0031033 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG14219 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG14219 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-7, Cele\oac-53, Cele\ndg-4, Cele\rhy-1, Cele\oac-55, Cele\oac-9, Cele\oac-6, Cele\oac-46, Cele\oac-31, Cele\oac-39, Cele\oac-3, Cele\oac-54, Cele\nrf-6, Cele\oac-14, Cele\oac-32, Cele\oac-50, Cele\oac-5, Cele\oac-20" Xtro\LOC101732251 Mmus\Oacyl - FBgn0265428 CR44340 - http://flybase.org/reports/FBgn0265428 non_protein_coding_gene - - - CR44340 - CR44340 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266997 alpha-Cat::shg alpha-Cat::shg http://flybase.org/reports/FBgn0266997 engineered_fusion_gene - - - "DEcad::alphaCat, DEcad-alpha-Cat, shg::alpha-Cat, alpha-Cat::shg" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0017450 abof about face http://flybase.org/reports/FBgn0017450 - gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available abof - - 11-Aug-17 DroID_v2017_08 - - - - - - "chordotonal organ & axon | lateral,commissure,longitudinal connective" FBgn0030376 CG2750 - http://flybase.org/reports/FBgn0030376 protein_coding_gene - - - "anon-WO0140519.124, CG2750" - CG2750 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-125o16.4, Drer\si:ch1073-392o20.2" - Cele\F20C5.6 - "Mmus\Tgoln1, Mmus\Champ1" "Hsap\TGOLN2, Hsap\CHAMP1" "viable,fertile" FBgn0033458 CG18446 - http://flybase.org/reports/FBgn0033458 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG18446 IPR013087:Zinc finger C2H2-type CG18446 11-Aug-17 DroID_v2017_08 Drer\si:dkey-208k4.2 Scer\PZF1 "Cele\mep-1, Cele\pzf-1" - - Hsap\ZBTB24 FBgn0033480 mRpL42 mitochondrial ribosomal protein L42 http://flybase.org/reports/FBgn0033480 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y6G3 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:N46796 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:N46796 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y6G3 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:N46796 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y6G3 "CG12921, MRPL31, MRP-S32, BcDNA:RE72116, mRpS32, mRpL42" "IPR019346:Ribosomal protein S32, mitochondrial" CG12921 11-Aug-17 DroID_v2017_08 Drer\mrpl42 - Cele\lpl-1 Xtro\mrpl42 Mmus\Mrpl42 Hsap\MRPL42 "viable,visible" trichogen cell DRSC06235 K -0.463332973 -0.664110389 -0.623800943 0.100174478 1.594816047 1.992712776 FBgn0038725 CG6184 - http://flybase.org/reports/FBgn0038725 protein_coding_gene - - - CG6184 - CG6184 11-Aug-17 DroID_v2017_08 "Drer\fam234b, Drer\fam234a" - - Xtro\fam234a "Mmus\Fam234a, Mmus\Fam234b" "Hsap\FAM234A, Hsap\FAM234B" viable FBgn0025562 anon-36Aa anon-36Aa http://flybase.org/reports/FBgn0025562 - gene - - - "cDNA I, anon-36Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065591 l(2)SH0901 lethal (2) SH0901 http://flybase.org/reports/FBgn0065591 gene - - - "l(2)SH0901, l(2)SH2 0901" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039767 CG2218 - http://flybase.org/reports/FBgn0039767 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:2154658 ubiquitin-ubiquitin ligase activity ; GO:0034450 | inferred from sequence or structural similarity with MGI:MGI:2154658 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:2154658 nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:2154658 "CG2218, UIP5" "IPR003613:U box domain, IPR017907:Zinc finger, RING-type, conserved site, IPR008979:Galactose-binding domain-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2218 11-Aug-17 DroID_v2017_08 "Drer\ube4a, Drer\ubox5" Scer\UFD2 - "Xtro\ube4a, Xtro\ube4b, Xtro\ubox5" "Mmus\Ube4b, Mmus\Ube4a, Mmus\Ubox5" "Hsap\UBOX5, Hsap\UBE4A, Hsap\UBE4B" viable FBgn0015386 en::ftz en::ftz http://flybase.org/reports/FBgn0015386 - engineered_fusion_gene - - - en::ftz - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" denticle belt FBgn0026261 bonsai bonsai http://flybase.org/reports/FBgn0026261 FBgn0034749 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82914 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82913 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82914 regulation of growth ; GO:0040008 | inferred from mutant phenotype mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:P82913 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82914 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82913 mitochondrion ; GO:0005739 | inferred from direct assay "DmMRPS15, MRP-S15, CG4207, mRpS15, bonsai" "IPR000589:Ribosomal protein S15, IPR009068:S15/NS1, RNA-binding, IPR005290:Ribosomal protein S15, bacterial-type" CG4207 11-Aug-17 DroID_v2017_08 Drer\mrps15 Scer\MRPS28 "Cele\mrps-15, Cele\vet-1" Xtro\mrps15 Mmus\Mrps15 Hsap\MRPS15 " embryonic stage -- adult stage , embryonic stage | extended germ band , larval stage , embryonic stage | late , embryonic stage | early " " anterior midgut inclusive primordium && posterior midgut inclusive primordium

, larval midgut

, embryonic midgut | restricted

, organism | ubiquitous

" "visible,recessive,size defective,developmental rate defective,lethal - all die before end of larval stage,partially,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,viable" "adult,anterior larval midgut & mitochondrion,trichogen cell,mesothoracic tergum" FBgn0266540 CG45101 - http://flybase.org/reports/FBgn0266540 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45101, Dmel_SuUR_uORF" - CG45101 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044081 E(rst)H42 E(rst)H42 http://flybase.org/reports/FBgn0044081 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H42, E(rst)H42" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003088 Pin Pin http://flybase.org/reports/FBgn0003088 - gene - - - "Tac, Pin" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable,visible,dominant" "macrochaeta,heat sensitive,mesothoracic bristle,metathoracic bristle,wing,female,scutellar bristle,thorax & macrochaeta,adult cuticle,cuticle" FBgn0265053 CR44168 - http://flybase.org/reports/FBgn0265053 non_protein_coding_gene - - - CR44168 - CR44168 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051088 CG31088 - http://flybase.org/reports/FBgn0051088 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31088 - CG31088 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003286 Rst(1)str Resistant to streptomycin http://flybase.org/reports/FBgn0003286 - gene - - - "str-R, Rst(1)str" - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical resistant ribosome FBgn0260046 33AA14 - http://flybase.org/reports/FBgn0260046 gene - - - 33AA14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0028116 l(3)S063813 lethal (3) S063813 http://flybase.org/reports/FBgn0028116 gene - - - "0638/13, l(3)S063813" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031474 CG2991 - http://flybase.org/reports/FBgn0031474 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG2991, CT42388, CT10107" "IPR011016:Zinc finger, RING-CH-type, IPR009457:Domain of unknown function DUF1084, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2991 11-Aug-17 DroID_v2017_08 "Drer\march9, Drer\march8, Drer\zgc:153256, Drer\march6, Drer\zgc:158785, Drer\march11, Drer\march4, Drer\march2, Drer\march7" Scer\SSM4 Cele\marc-3 "Xtro\march1, Xtro\march9, Xtro\march3, Xtro\march8, Xtro\march7, Xtro\march2, Xtro\march11, Xtro\march4" "Mmus\March4, Mmus\March3, Mmus\March11, Mmus\March1, Mmus\March8, Mmus\March2, Mmus\March10, Mmus\March6, Mmus\March9" "Hsap\MARCH9, Hsap\MARCH1, Hsap\MARCH3, Hsap\MARCH10, Hsap\MARCH11, Hsap\MARCH8, Hsap\MARCH7, Hsap\MARCH6, Hsap\MARCH4, Hsap\MARCH2" viable FBgn0000917 fs(1)ne3 female sterile (1) no eggs 3 http://flybase.org/reports/FBgn0000917 - gene - - - "ne3, fs(1)ne[3], fs(1)ne3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,female sterile germline-dependent" "endochorion,dorsal appendage,chorion,oocyte" FBgn0261843 pre-mod(mdg4)-W - http://flybase.org/reports/FBgn0261843 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-W, CG42775, RW" "IPR007588:Zinc finger, FLYWCH-type" CG42775 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038630 CG14305 - http://flybase.org/reports/FBgn0038630 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:30410 protein kinase activity ; GO:0004672 | non-traceable author statement" intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:30410 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 CG14305 "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG14305 11-Aug-17 DroID_v2017_08 Drer\tssk6 "Scer\KIN4, Scer\FRK1" "Cele\Y38H8A.4, Cele\W02B12.12, Cele\F23C8.8, Cele\C27D6.11, Cele\tag-344, Cele\kin-33" - "Mmus\Tssk4, Mmus\Tssk6, Mmus\Tssk1, Mmus\Tssk3, Mmus\Tssk2" "Hsap\TSSK6, Hsap\TSSK4, Hsap\TSSK1B, Hsap\TSSK3, Hsap\TSSK2" viable DRSC14784 K -0.041856088 0.610597618 -0.185199853 0.252780545 1.538494444 -0.094858458 FBgn0005459 l(1)v459 lethal (1) v459 http://flybase.org/reports/FBgn0005459 - gene - - - "l(1)459, l(1)v459" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028029 l(3)S103012b lethal (3) S103012b http://flybase.org/reports/FBgn0028029 gene - - - "1030/12, l(3)S103012, l(3)S103012b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062591 Mod(var)1557 Mod(var)1557 http://flybase.org/reports/FBgn0062591 gene - - - "1557, Mod(var)1557" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,partially lethal - majority die,recessive" FBgn0003739 Tpl Triplolethal http://flybase.org/reports/FBgn0003739 - gene - - - "tpl, Tpl" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041716 srn stern http://flybase.org/reports/FBgn0041716 gene - - - srn - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,chemical resistant,dominant,recessive,melanotic mass phenotype,tumorigenic" "salivary gland,polytene chromosome,melanotic mass,embryonic/larval brain" FBgn0053012 CG33012 - http://flybase.org/reports/FBgn0053012 protein_coding_gene - - - "CG30041, CG13161, CG33012" IPR007484:Peptidase M28 CG33012 11-Aug-17 DroID_v2017_08 Drer\LOC100330918 "Scer\YDR415C, Scer\APE3, Scer\VPS70, Scer\PFF1" "Cele\C44B7.11, Cele\B0495.7" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0083984 CG34148 - http://flybase.org/reports/FBgn0083984 protein_coding_gene - - - CG34148 IPR029245:Protein of unknown function DUF4528 CG34148 11-Aug-17 DroID_v2017_08 "Drer\aldh4a1, Drer\zgc:162898" Scer\PUT2 Cele\alh-6 "Xtro\aldh4a1, Xtro\c15orf61" "Mmus\2300009A05Rik, Mmus\Aldh4a1" "Hsap\ALDH4A1, Hsap\C15orf61" FBgn0005132 l(1)Y8 lethal (1) Y8 http://flybase.org/reports/FBgn0005132 - gene - - - l(1)Y8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0058292 CG40292 - http://flybase.org/reports/FBgn0058292 protein_coding_gene - - - CG40292 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040877 CG12994 - http://flybase.org/reports/FBgn0040877 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12994 - CG12994 11-Aug-17 DroID_v2017_08 - Scer\ZRG17 - - - Hsap\AP3B1 viable DRSC19514 IE -0.601459047 -1.978444665 1.602566356 -0.058730736 0.15757832 -0.632486273 FBgn0052360 tRNA:Leu-CAG-1-4 transfer RNA:Leucine-CAG 1-4 http://flybase.org/reports/FBgn0052360 tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "AE002602.trna8-LeuCAG, tRNA:L:CAG:AE002602-d, CR32360, chr3L.trna42-LeuCAG, tRNA-Leu-CAG-1-4, tRNA:Leu-CAG-1-4, tRNA:CR32360, CUG" - CR32360 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027997 l(3)S123208 lethal (3) S123208 http://flybase.org/reports/FBgn0027997 gene - - - "1282/02, 1232/08, 0542/11, l(3)S123208" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025129 su(RpII140[Z36])S18 su(RpII140[Z36])S18 http://flybase.org/reports/FBgn0025129 - gene - - - "Z36[S18], su(RpII140[Z36])S18" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0250869 CG42240 - http://flybase.org/reports/FBgn0250869 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42240, CG15893" - CG42240 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013403 anon-14Bb anon-14Bb http://flybase.org/reports/FBgn0013403 FBgn0014079 gene - - - anon-14Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage FBgn0039948 CG17865 - http://flybase.org/reports/FBgn0039948 protein_coding_gene - - - CG17865 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036329 CG11262 - http://flybase.org/reports/FBgn0036329 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004680 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004680 CG11262 IPR004680:Citrate transporter-like domain CG11262 11-Aug-17 DroID_v2017_08 Drer\oca2 - Cele\srh-98 Xtro\oca2 Mmus\Oca2 Hsap\OCA2 viable FBgn0030122 CG16892 - http://flybase.org/reports/FBgn0030122 protein_coding_gene molecular_function ; GO:0003674 | no biological data available nucleocytoplasmic transport ; GO:0006913 | inferred from sequence or structural similarity with HGNC:13666 nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with HGNC:13666 endomembrane system ; GO:0012505 | inferred from direct assay "CG16892, Aladin" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG16892 11-Aug-17 DroID_v2017_08 "Drer\glis2a, Drer\glis2b, Drer\LOC100333406, Drer\glis3, Drer\aaas" - - "Xtro\glis3, Xtro\aaas, Xtro\glis2" "Mmus\Glis2, Mmus\Aaas, Mmus\Glis1" "Hsap\GLIS2, Hsap\GLIS1, Hsap\AAAS, Hsap\GLIS3" "viable,fertile" FBgn0002051 l(2)37Fd lethal (2) 37Fd http://flybase.org/reports/FBgn0002051 - gene - - - "l(2)OE55, l(2)37Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013706 mt:tRNA:Ser-TGA mitochondrial transfer RNA:Serine-TGA http://flybase.org/reports/FBgn0013706 FBgn0002867 tRNA_gene - - - "CR34091, tRNA[Ser(UCN)], mt-tRNA[Ser] (UGA), tRNA-Ser, mtdbD00006311, tRNA[Ser], mt:tRNA:Ser-TGA, mt:tRNA:S:UCN" - CR34091 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003278 RpI135 RNA polymerase I 135kD subunit http://flybase.org/reports/FBgn0003278 FBgn0021812 protein_coding_gene "ribonucleoside binding ; GO:0032549 | inferred from electronic annotation with InterPro:IPR015712 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007120, InterPro:IPR007121, InterPro:IPR007641, InterPro:IPR007642, InterPro:IPR007644, InterPro:IPR007645 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000465942" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR007120, InterPro:IPR007121, InterPro:IPR007641, InterPro:IPR007642, InterPro:IPR007644, InterPro:IPR007645, InterPro:IPR009674, InterPro:IPR015712 neurogenesis ; GO:0022008 | inferred from mutant phenotype cell growth ; GO:0016049 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype" DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN000465942 "RP135, DmRP135, l(2)k16513, RpIII135, CG4033, RpI135, RPI135, Rpl135" "IPR015712:DNA-directed RNA polymerase, subunit 2, IPR007120:DNA-directed RNA polymerase, subunit 2, domain 6, IPR007121:RNA polymerase, beta subunit, conserved site, IPR007641:RNA polymerase Rpb2, domain 7, IPR007642:RNA polymerase Rpb2, domain 2, IPR007644:RNA polymerase, beta subunit, protrusion, IPR007645:RNA polymerase Rpb2, domain 3, IPR009674:DNA-directed RNA polymerase I subunit RPA2, domain 4" CG4033 11-Aug-17 DroID_v2017_08 Drer\polr1b Scer\RPA135 Cele\rpoa-2 Xtro\polr1b Mmus\Polr1b Hsap\POLR1B adult stage "viable,lethal,developmental rate defective,decreased cell size,somatic clone,recessive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval hemocyte | third instar larval stage,embryonic/larval fat body,somatic clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0014071 TART-element\gag TART-open reading frame 1 http://flybase.org/reports/FBgn0014071 - transposable_element_gene - - "nucleus ; GO:0005634 | inferred from direct assay chromosome, telomeric region ; GO:0000781 | inferred from direct assay" "TART A ORF1, gag, ORF1, TART-repeat\ORF1, TART-element\ORF1, TART-element\gag, TART ORF1, TART gag, TART Gag" IPR006579:Pre-C2HC domain - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030101 CG12118 - http://flybase.org/reports/FBgn0030101 protein_coding_gene - cobalamin metabolic process ; GO:0009235 | inferred from electronic annotation with InterPro:IPR019362 - CG12118 IPR019362:Methylmalonic aciduria and homocystinuria type D protein CG12118 11-Aug-17 DroID_v2017_08 "Drer\mmadhc, Drer\zgc:92335" - Cele\Y76A2B.5 Xtro\mmadhc Mmus\Mmadhc Hsap\MMADHC viable FBgn0030373 CG12721 - http://flybase.org/reports/FBgn0030373 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE60404, CG12721" - CG12721 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female sterile" FBgn0003050 pod-foot pod foot http://flybase.org/reports/FBgn0003050 - gene - - - "pdf, pod-foot" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,fertile,viable" "pretarsus,tarsal segment 3,tarsal segment 4,tarsal segment" FBgn0050469 Ir52b Ionotropic receptor 52b http://flybase.org/reports/FBgn0050469 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir52b, CG12961, DmelIR52b, CG30469, IR52b, IF52b" - CG30469 11-Aug-17 DroID_v2017_08 - - Cele\glr-7 - - - viable FBgn0039277 CG13650 - http://flybase.org/reports/FBgn0039277 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753" - CG13650 "IPR000718:Peptidase M13, IPR024079:Metallopeptidase, catalytic domain, IPR008753:Peptidase M13, N-terminal domain" CG13650 11-Aug-17 DroID_v2017_08 "Drer\phex, Drer\ece2b, Drer\mmel1, Drer\ece1" - - "Xtro\ecel1, Xtro\ece1, Xtro\ece2, Xtro\mmel1" "Mmus\Ece1, Mmus\Kel, Mmus\Mme, Mmus\Ecel1, Mmus\Ece2, Mmus\Mmel1, Mmus\Phex" "Hsap\ECE1, Hsap\MMEL1, Hsap\PHEX, Hsap\KEL, Hsap\ECE2, Hsap\MME, Hsap\ECEL1" viable FBgn0024362 Naa30A N(alpha)-acetyltransferase 30 A http://flybase.org/reports/FBgn0024362 - protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from sequence or structural similarity with UniProtKB:Q147X3 peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from biological aspect of ancestor with PANTHER:PTN000558065 N-terminal peptidyl-methionine acetylation ; GO:0017196 | inferred from sequence or structural similarity with UniProtKB:Q147X3 N-terminal protein amino acid acetylation ; GO:0006474 | inferred from biological aspect of ancestor with PANTHER:PTN000558065 histone acetylation ; GO:0016573 | inferred from mutant phenotype NatC complex ; GO:0031417 | inferred from sequence or structural similarity with UniProtKB:Q147X3 NatC complex ; GO:0031417 | inferred from biological aspect of ancestor with PANTHER:PTN000558222 "EG:8D8.6, DmAAF45606, NAA30, CG11412, Naa30, Naa30A" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG11412 11-Aug-17 DroID_v2017_08 Drer\naa30 Scer\MAK3 Cele\natc-2 "Xtro\naa30, Xtro\cml" "Mmus\Nat8f7, Mmus\Nat8f6, Mmus\Nat8f5, Mmus\Nat8f3, Mmus\Naa30" "Hsap\NAA30, Hsap\NAT8" "viable,fertile" FBgn0039398 CG14540 - http://flybase.org/reports/FBgn0039398 protein_coding_gene - - - CG14540 IPR006990:Tweety CG14540 11-Aug-17 DroID_v2017_08 "Drer\ttyh2, Drer\ttyh3b, Drer\ttyh2l, Drer\ttyh1, Drer\ttyh3a" - Cele\ttyh-1 - "Mmus\Ttyh1, Mmus\Ttyh2, Mmus\Ttyh3" "Hsap\TTYH2, Hsap\TTYH1, Hsap\TTYH3" viable DRSC14884 IEK -1.564750473 -1.524808493 -1.861985442 0.676072232 2.444436797 1.002984555 FBgn0259715 CG42369 - http://flybase.org/reports/FBgn0259715 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG9511, CG9508, CG33295, CG13981, CG42369, CT26922" - CG42369 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0267957 CR46237 - http://flybase.org/reports/FBgn0267957 non_protein_coding_gene - - - "CR46237, lincRNA.294" - CR46237 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000552 Edg84A Ecdysone-dependent gene 84A http://flybase.org/reports/FBgn0000552 "FBgn0004776, FBtr0081688, FBpp0081186" protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of pupal chitin-based cuticle ; GO:0008011 | traceable author statement chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "EDG84A, CG2345, EDG-84, EDG84, DM-EDG84, EDG-84A, cc1, Edg84, BG:DS00004.8, Edg84A, DmelEDG84A" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2345 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - prepupal stage epidermis

"viable,visible" trichogen cell FBgn0004565 l(3)63Da lethal (3) 63Da http://flybase.org/reports/FBgn0004565 - gene - - - l(3)63Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0029676 HIP-R Hsc/Hsp70-interacting protein related http://flybase.org/reports/FBgn0029676 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR034649 heat shock protein binding ; GO:0031072 | inferred from sequence or structural similarity with UniProtKB:P50503 chaperone binding ; GO:0051087 | inferred from sequence or structural similarity with UniProtKB:P50503 Hsp70 protein binding ; GO:0030544 | inferred from sequence or structural similarity with UniProtKB:P50503 chaperone cofactor-dependent protein refolding ; GO:0070389 | inferred from sequence or structural similarity with UniProtKB:P50503 protein complex ; GO:0043234 | inferred from sequence or structural similarity with UniProtKB:P50503 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P50503 "anon-EST:fe1A9, HIP-R, CG2947, Hip" "IPR006636:Heat shock chaperonin-binding, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR034649:Hsp70-interacting protein, N-terminal" CG2947 11-Aug-17 DroID_v2017_08 Drer\st13 Scer\SGT1 Cele\hip-1 Xtro\st13 Mmus\St13 Hsap\ST13 FBgn0060983 l(3)S028304 lethal (3) S028304 http://flybase.org/reports/FBgn0060983 gene - - - "0283/04, l(3)S028304" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260942 bond james bond http://flybase.org/reports/FBgn0260942 protein_coding_gene "fatty acid elongase activity ; GO:0009922 | inferred from genetic interaction with SGD:S000000630,SGD:S000004364" "spindle assembly ; GO:0051225 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype very long-chain fatty acid biosynthetic process ; GO:0042761 | inferred from sequence or structural similarity with HGNC:14415 inferred from genetic interaction with SGD:S000000630,SGD:S000004364 meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype pheromone biosynthetic process ; GO:0042811 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype fatty acid elongation ; GO:0030497 | inferred from genetic interaction with SGD:S000000630,SGD:S000004364" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 integral component of membrane ; GO:0016021 | inferred from sequence model "CG6921, James bond, bond" "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG6921 11-Aug-17 DroID_v2017_08 "Drer\elovl7b, Drer\elovl1b, Drer\elovl4b, Drer\hsd17b8, Drer\elovl4a, Drer\elovl2, Drer\dhrs7, Drer\elovl8b, Drer\elovl7a, Drer\elovl1a, Drer\zgc:101858, Drer\elovl5, Drer\elovl8a" "Scer\ELO2, Scer\ELO3, Scer\ELO1" "Cele\Y47G6A.21, Cele\Y47G6A.22, Cele\ZK829.1, Cele\elo-9, Cele\dhs-11, Cele\dhs-14, Cele\F28H7.2, Cele\dhs-25, Cele\F26D2.15, Cele\C06E4.3, Cele\F25D1.5" "Xtro\elovl2, Xtro\elovl1, Xtro\elovl5, Xtro\MGC79752, Xtro\elovl7, Xtro\hsd17b8, Xtro\cbr4, Xtro\dhrs7" "Mmus\Elovl1, Mmus\Elovl3, Mmus\Elovl4, Mmus\Elovl7, Mmus\Cbr4, Mmus\Elovl2, Mmus\H2-Ke6, Mmus\Dhrs7, Mmus\Elovl5" "Hsap\ELOVL1, Hsap\HSD17B8, Hsap\ELOVL7, Hsap\ELOVL5, Hsap\ELOVL4, Hsap\CBR4, Hsap\DHRS7, Hsap\ELOVL3, Hsap\ELOVL2" FBgn0034569 dgt3 dim gamma-tubulin 3 http://flybase.org/reports/FBgn0034569 protein_coding_gene - regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype HAUS complex ; GO:0070652 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "Dgt3, CG3221, dgt3, dim" "IPR032733:HAUS augmin-like complex subunit 3, N-terminal" CG3221 11-Aug-17 DroID_v2017_08 - - Cele\grdn-1 - - - viable FBgn0025591 His2BPsi Histone H2B pseudogene http://flybase.org/reports/FBgn0025591 - pseudogene_attribute - - - "PsiH2B, His2BPsi" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265062 CR44173 - http://flybase.org/reports/FBgn0265062 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44173, CR44173, lincRNA.809" - CR44173 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028131 l(3)S051309 lethal (3) S051309 http://flybase.org/reports/FBgn0028131 gene - - - "0513/09, l(3)S051309" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable" FBgn0052404 Cpr65Aw Cuticular protein 65Aw http://flybase.org/reports/FBgn0052404 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG10461, Cpr65Aw, CG32404, DmelCpr65Aw, C32404" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG32404 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\F44F1.4, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0039479 CG14257 - http://flybase.org/reports/FBgn0039479 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14257 - CG14257 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002306 sas stranded at second http://flybase.org/reports/FBgn0002306 - protein_coding_gene receptor activity ; GO:0004872 | non-traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | non-traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay "Sas, rfd, l(3)84Cd, CG2507, sas, SAS" "IPR001007:VWFC domain, IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold" CG2507 11-Aug-17 DroID_v2017_08 Drer\ptprq - - - - - " adult stage , embryonic stage | stage 15,16 , larval stage | third instar , larval stage , embryonic stage | stage 12-16 , embryonic stage | stage 15-16 " " mouthpart

, trachea

, imaginal disc

, wing

, epidermis

, eye

, embryonic/larval esophagus

, embryonic/larval foregut

, embryonic/larval pharynx

, embryonic/larval proventriculus

, reproductive system

, leg

, embryonic/larval hindgut

" "some die during larval stage,partially lethal - majority die,viable,fertile,lethal - all die before end of larval stage,polyphasic,cold sensitive,lethal,recessive,neuroanatomy defective" "embryonic/larval cuticle,embryonic/larval trachea,embryonic/larval tracheal system,longitudinal connective,anterior commissure,longitudinal connective | embryonic stage 16" FBgn0044087 E(rst)E370 E(rst)E370 http://flybase.org/reports/FBgn0044087 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E370, E(rst)E370" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "eye,retina" FBgn0266951 CR45402 - http://flybase.org/reports/FBgn0266951 non_protein_coding_gene - - - CR45402 - CR45402 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060964 l(3)S032110 lethal (3) S032110 http://flybase.org/reports/FBgn0060964 gene - - - "0321/10, l(3)S032110" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026150 ApepP Aminopeptidase P http://flybase.org/reports/FBgn0026150 - protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG6291, DAP-P, AP-P, Daminopep-p, ApepP, Apep[P]" "IPR000994:Peptidase M24, IPR000587:Creatinase, N-terminal, IPR033740:Aminopeptidase P, IPR029149:Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR028980:Creatinase/Aminopeptidase P, N-terminal, IPR032416:Peptidase M24, C-terminal domain" CG6291 11-Aug-17 DroID_v2017_08 "Drer\xpnpep1, Drer\xpnpep2" Scer\FRA1 "Cele\app-1, Cele\Y45G5AM.2" Xtro\xpnpep2 "Mmus\Xpnpep2, Mmus\Xpnpep1" "Hsap\XPNPEP2, Hsap\XPNPEP1" FBgn0264485 CR43893 - http://flybase.org/reports/FBgn0264485 non_protein_coding_gene - - - CR43893 - CR43893 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038380 CG14877 - http://flybase.org/reports/FBgn0038380 protein_coding_gene guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG14877, DrGC-2, Gyc89A" "IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I" CG14877 11-Aug-17 DroID_v2017_08 "Drer\gucy2c, Drer\gc2, Drer\gucy2g, Drer\gucy2f, Drer\npr1b, Drer\npr1a, Drer\npr3, Drer\si:ch73-139e5.4, Drer\gc3, Drer\si:dkey-37g12.1" - "Cele\gcy-23, Cele\gcy-37, Cele\acy-3, Cele\gcy-12, Cele\gcy-18, Cele\gcy-14" "Xtro\gucy2f, Xtro\npr1, Xtro\gucy2d, Xtro\npr3, Xtro\gucy2c" "Mmus\Gucy2e, Mmus\Gucy2g, Mmus\Npr3, Mmus\Npr2, Mmus\Gucy2f, Mmus\Gucy2d, Mmus\Npr1, Mmus\Gucy2c" "Hsap\GUCY2F, Hsap\NPR2, Hsap\NPR3, Hsap\GUCY2C, Hsap\NPR1, Hsap\GUCY2D" "partially lethal - majority die,some die during pupal stage" FBgn0027932 Akap200 A kinase anchor protein 200 http://flybase.org/reports/FBgn0027932 protein_coding_gene protein kinase A binding ; GO:0051018 | inferred from physical interaction with Pka-R2 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern lipid particle ; GO:0005811 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "akap200, AKAP200, DAKAP200, EP(2)2254, dpo, MESR2, CG13388, BcDNA:LP02734, anon-WO0118547.213, anon-WO0118547.134, Akap200, Akap 200" - CG13388 11-Aug-17 DroID_v2017_08 - - - Xtro\akap12 - - " embryonic stage -- adult stage , adult stage " adult head

"viable,reduced,lethal,recessive,visible,wild-type,fertile,female fertile,hyperactive,conditional,chemical resistant" "mesothoracic tergum & chaeta | supernumeraryN22-14),nurse cell,egg chamber,mesothoracic tergum & macrochaeta | supernumeraryN22-14),inner nurse cell ring canal rim,outer nurse cell ring canal rim,antenna,wing vein,wing" FBgn0263992 CR43735 - http://flybase.org/reports/FBgn0263992 non_protein_coding_gene - - - CR43735 - CR43735 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031283 CG15880 - http://flybase.org/reports/FBgn0031283 protein_coding_gene - - - CG15880 IPR019402:Frag1/DRAM/Sfk1 CG15880 11-Aug-17 DroID_v2017_08 Drer\pgap2 Scer\CWH43 "Cele\F36H9.5, Cele\Y11D7A.9, Cele\F49E12.12, Cele\Y38F1A.8, Cele\C14B9.3, Cele\ZK185.4, Cele\T23B12.5, Cele\tag-189" - "Mmus\Cwh43, Mmus\Pgap2" "Hsap\CWH43, Hsap\PGAP2" viable FBgn0053407 5SrRNA:CR33407 5SrRNA:CR33407 http://flybase.org/reports/FBgn0053407 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33407, 5SrRNA:CR33407" - CR33407 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086444 l(2)37Cb lethal (2) 37Cb http://flybase.org/reports/FBgn0086444 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002464 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000000815 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000434013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000005294 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000005294 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "l(2)37Cb, CG10689, Cb, l(2)E104, cg10689" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011709:Domain of unknown function DUF1605, IPR007502:Helicase-associated domain, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR001650:Helicase, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain" CG10689 11-Aug-17 DroID_v2017_08 "Drer\dhx32b, Drer\dhx38, Drer\dhx16, Drer\dhx15, Drer\dhx8, Drer\dhx32a, Drer\zgc:158828, Drer\dhx33" "Scer\PRP22, Scer\PRP2, Scer\PRP16, Scer\PRP43" "Cele\let-355, Cele\mog-1, Cele\mog-5, Cele\mog-4, Cele\ddx-15" "Xtro\dhx38, Xtro\dhx35, Xtro\dhx8, Xtro\dhx16, Xtro\dhx15, Xtro\dhx33" "Mmus\Dhx15, Mmus\Dhx32, Mmus\Dhx38, Mmus\Dhx35, Mmus\Dhx16, Mmus\Dqx1, Mmus\Dhx8, Mmus\Dhx33" "Hsap\DHX32, Hsap\DHX35, Hsap\DHX33, Hsap\DQX1, Hsap\DHX8, Hsap\DHX38, Hsap\DHX15, Hsap\DHX16" FBgn0260873 CG42583 - http://flybase.org/reports/FBgn0260873 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42583 - CG42583 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034407 DptB Diptericin B http://flybase.org/reports/FBgn0034407 protein_coding_gene - humoral immune response ; GO:0006959 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "DptB, Dpt, DiptB, 147473_at, Diptericin, CG10794, dptlp, BcDNA:RH29451, dpt B, Diptericin B, dptB, diptB" "IPR005521:Attacin, C-terminal" CG10794 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0017361 l(3)C106 lethal (3) C106 http://flybase.org/reports/FBgn0017361 - gene - - - "C106, l(3)C106" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0011391 l(3)j6B4 lethal (3) j6B4 http://flybase.org/reports/FBgn0011391 - gene - - - "l(3)J6B4, l(3)j6B4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032801 CG10165 - http://flybase.org/reports/FBgn0032801 protein_coding_gene - - - CG10165 IPR006593:Cytochrome b561/ferric reductase transmembrane CG10165 11-Aug-17 DroID_v2017_08 "Drer\cyb561d2, Drer\cyb561d1" - - Xtro\cyb561d2 "Mmus\Cyb561d1, Mmus\Cyb561d2" "Hsap\CYB561D2, Hsap\CYB561D1" viable FBgn0044871 Gos28 "Golgi SNARE, 28 kDa" http://flybase.org/reports/FBgn0044871 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with SGD:S000001023 SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000473329 SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000473329 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity "intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000473329 regulation of vesicle targeting, to, from or within Golgi ; GO:0048209 | inferred from mutant phenotype vesicle fusion ; GO:0006906 | inferred from sequence or structural similarity with SGD:S000001023 vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000473329 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with UniProtKB:O08522 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with UniProtKB:O08522 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000473329 Golgi vesicle transport ; GO:0048193 | inferred from sequence or structural similarity with SGD:S000001023" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR023601 SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000473329 cis-Golgi network ; GO:0005801 | inferred from biological aspect of ancestor with PANTHER:PTN000473329 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with SGD:S000001023 membrane ; GO:0016020 | inferred from direct assay Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000473329 Golgi medial cisterna ; GO:0005797 | inferred from biological aspect of ancestor with PANTHER:PTN000473329 Golgi trans cisterna ; GO:0000138 | inferred from sequence or structural similarity with UniProtKB:O08522 "CG7700, dgos28, GOS28, Gos28, gos28, FSG28, dGos28" "IPR023601:Golgi SNAP receptor complex, subunit 1" CG7700 11-Aug-17 DroID_v2017_08 Drer\gosr1 Scer\GOS1 Cele\gos-28 Xtro\gosr1 Mmus\Gosr1 Hsap\GOSR1 "viable,fertile" DRSC22859 E 0.906258817 0.626511151 0.87016003 2.004989606 0.936239691 1.26130472 FBgn0085345 CG34316 - http://flybase.org/reports/FBgn0085345 protein_coding_gene - - - "CG34316, Dm_3R:60797, JHBP" IPR010562:Haemolymph juvenile hormone binding CG34316 11-Aug-17 DroID_v2017_08 - - Cele\fbxa-14 - - - FBgn0005442 l(1)v139 lethal (1) v139 http://flybase.org/reports/FBgn0005442 - gene - - - "l(1)139, l(1)v139" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035440 CG14969 - http://flybase.org/reports/FBgn0035440 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytosol ; GO:0005829 | inferred from sequence or structural similarity with MGI:MGI:2655574 CG14969 IPR019172:Osteopetrosis-associated transmembrane protein 1 precursor CG14969 11-Aug-17 DroID_v2017_08 Drer\ostm1 - Cele\F42A8.3 Xtro\ostm1 Mmus\Ostm1 Hsap\OSTM1 viable FBgn0067657 sd-10 sd-10 http://flybase.org/reports/FBgn0067657 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,somatic clone,lethal,recessive,phototaxis defective" FBgn0053796 CG33796 - http://flybase.org/reports/FBgn0053796 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33796 IPR010512:Protein of unknown function DUF1091 CG33796 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002225 l(3)68Ae lethal (3) 68Ae http://flybase.org/reports/FBgn0002225 FBgn0002226 gene - - - "l(3)68Ae', l(3)C206, J, l(3)J, l(3)68Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0051890 tRNA:Asp-GTC-1-8 transfer RNA:Aspartic acid-GTC 1-8 http://flybase.org/reports/FBgn0051890 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "AE002690.trna8-AspGTC, tRNA:asp2:29E, tRNA:D2:29E, tRNA:D:GTC:AE002690-d, CR31890, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna17-AspGTC, tRNA:Asp-GTC-1-8, tRNA:CR31890, tRNA-Asp-GTC-1-8, GAC" - CR31890 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267035 CR45479 - http://flybase.org/reports/FBgn0267035 non_protein_coding_gene - - - CR45479 - CR45479 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050354 UQCR-11L Ubiquinol-cytochrome c reductase 11 kDa subunit-like http://flybase.org/reports/FBgn0050354 protein_coding_gene ubiquinol-cytochrome-c reductase activity ; GO:0008121 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000393767 "mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with SGD:S000001929 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000393767 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000393767" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN000393767 "NEST:bs01g03, CG30354, UCRH, UQCR-11L" "IPR003422:Cytochrome b-c1 complex, subunit 6, IPR023184:Ubiquinol-cytochrome C reductase hinge domain" CG30354 11-Aug-17 DroID_v2017_08 Drer\uqcrh Scer\QCR6 Cele\T27E9.2 Xtro\uqcrh Mmus\Uqcrh "Hsap\UQCRH, Hsap\UQCRHL" viable FBgn0011181 l(1)291-100 lethal (1) 291-100 http://flybase.org/reports/FBgn0011181 FBgn0010199 gene - - - "291-100, l(1)291-100" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0004220 l(3)84Fh lethal (3) 84Fh http://flybase.org/reports/FBgn0004220 - gene - - - l(3)84Fh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263001 CR43309 - http://flybase.org/reports/FBgn0263001 non_protein_coding_gene - - - "CR43309, lincRNA.648" - CR43309 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262559 Mdh2 Malate dehydrogenase 2 http://flybase.org/reports/FBgn0262559 protein_coding_gene L-malate dehydrogenase activity ; GO:0030060 | inferred from sequence or structural similarity with UniProtKB:P40926 malate dehydrogenase activity ; GO:0016615 | inferred from direct assay malate metabolic process ; GO:0006108 | inferred from electronic annotation with InterPro:IPR010097 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR015955 activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P40926 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype positive regulation of programmed cell death ; GO:0043068 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype pupal development ; GO:0035209 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P40926 lipid particle ; GO:0005811 | inferred from direct assay "mdh2, psg7, Mdh2, CG7998, MDH-2, Mdh, mMdh, l(3)psg7, CG 7998, MDH2" "IPR001236:Lactate/malate dehydrogenase, N-terminal, IPR001557:L-lactate/malate dehydrogenase, IPR010097:Malate dehydrogenase, type 1, IPR015955:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR016040:NAD(P)-binding domain, IPR022383:Lactate/malate dehydrogenase, C-terminal" CG7998 11-Aug-17 DroID_v2017_08 Drer\mdh2 "Scer\MDH2, Scer\MDH3, Scer\MDH1" Cele\mdh-2 Xtro\mdh2 Mmus\Mdh2 Hsap\MDH2 FBgn0039521 CG5402 - http://flybase.org/reports/FBgn0039521 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "anon-WO0140519.87, CG5402" - CG5402 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060941 l(3)S039606b lethal (3) S039606b http://flybase.org/reports/FBgn0060941 gene - - - "0396/06, l(3)S039606b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267559 CR45899 - http://flybase.org/reports/FBgn0267559 non_protein_coding_gene - - - "CR45899, lincRNA.701" - CR45899 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011725 twin twin http://flybase.org/reports/FBgn0011725 "FBgn0039166, FBgn0039168, FBgn0045815, FBgn0051137" protein_coding_gene poly(A)-specific ribonuclease activity ; GO:0004535 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 oogenesis ; GO:0048477 | inferred from mutant phenotype nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from direct assay negative regulation of translation ; GO:0017148 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay CCR4-NOT complex ; GO:0030014 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CCR4, ccr4, CG31137, CG17741, CT39331, twn, BEST:GH20274, CG5534, twin, Ccr4, Twin" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR005135:Endonuclease/exonuclease/phosphatase, IPR032675:Leucine-rich repeat domain, L domain-like" CG31137 11-Aug-17 DroID_v2017_08 "Drer\pde12, Drer\cnot6l, Drer\cnot6b, Drer\cnot6a, Drer\nocta" "Scer\NGL1, Scer\CCR4, Scer\NGL2" Cele\ccr-4 "Xtro\cnot6l, Xtro\noct" "Mmus\Lrrc27, Mmus\Cnot6, Mmus\Pde12, Mmus\Angel2, Mmus\Noct, Mmus\Cnot6l" "Hsap\NOCT, Hsap\PDE12, Hsap\CNOT6L, Hsap\CNOT6, Hsap\ANGEL2" "viable,female sterile,male fertile,lethal - all die before end of embryonic stage,maternal effect,partially,some die during embryonic stage,fertile,neuroanatomy defective" "egg chamber,nurse cell ring canal,supernumerary,oocyte,female germline stem cell,cell autonomous,germline clone,nurse cell,syncytial blastoderm embryo,maternal effect,embryonic head,embryonic/larval neuromuscular junction,type Ib terminal bouton | supernumerary | third instar larval stage" FBgn0003101 PL(2)sp-G2 Polygenic locus sternopleural G2 http://flybase.org/reports/FBgn0003101 - gene - - - "PL(2)sp[G2], PL(2)sp-G2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028896 CG17329 - http://flybase.org/reports/FBgn0028896 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:25539 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:25539 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:25539 "CG17329, DS02740.5, BG:DS02740.5, BcDNA:AT18988" "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17329 11-Aug-17 DroID_v2017_08 Drer\rfwd3 - "Cele\T01G5.7, Cele\F19G12.1" Xtro\rfwd3 Mmus\Rfwd3 Hsap\RFWD3 "viable,visible" trichogen cell FBgn0260437 CR42532 - http://flybase.org/reports/FBgn0260437 pseudogene_attribute - - - CR42532 - CR42532 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043892 l(1)U93 lethal (1) U93 http://flybase.org/reports/FBgn0043892 gene - - - l(1)U93 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/first instar larval cuticle,salivary gland" FBgn0005599 yemG3b yema gene 3b http://flybase.org/reports/FBgn0005599 FBgn0004042 gene - - - "yG3b, yT3b, yemG3b" - - 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage--adult stage , adult stage && oogenesis stage , embryonic stage -- adult stage , larval stage--pupal stage , embryonic stage | 12-18 hr , embryonic stage | embryonic stage <=8 " " spermatocyte

, ovary

, central nervous system | restricted

, imaginal disc

, hindgut

, organism

" FBgn0022289 l(2)05559b lethal (2) 05559b http://flybase.org/reports/FBgn0022289 - gene - - - l(2)05559b - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069310 X-28-2 X-28-2 http://flybase.org/reports/FBgn0069310 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-28-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,recessive,rescuable maternal effect" FBgn0262123 l(2)41Ab lethal (2) 41Ab http://flybase.org/reports/FBgn0262123 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "axoneme assembly ; GO:0035082 | inferred from biological aspect of ancestor with PANTHER:PTN000780552 cilium movement ; GO:0003341 | inferred from sequence or structural similarity with HGNC:26090,MGI:MGI:244389 epithelial cilium movement involved in determination of left/right asymmetry ; GO:0060287 | inferred from biological aspect of ancestor with PANTHER:PTN000780552 axonemal dynein complex assembly ; GO:0070286 | inferred from sequence or structural similarity with HGNC:26090" axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000780552 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:2443893 "l(2)41Ab, CG41265, 41Ab, l(2)EMS45-10, GroupI, l(2R)B, 1(2R)B, CG40214, CG40334" - CG41265 11-Aug-17 DroID_v2017_08 Drer\ccdc40 - - "Xtro\ccdc40, Xtro\ccdc88a" Mmus\Ccdc40 Hsap\CCDC40 FBgn0067312 CheB38a Chemosensory protein B 38a http://flybase.org/reports/FBgn0067312 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CG9329, 38E.23, CG33320, CheB38a" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster, IPR010512:Protein of unknown function DUF1091" CG33320 11-Aug-17 DroID_v2017_08 - - - - - - DRSC03205 I -0.290018803 -1.575845456 -0.474739078 -0.083109136 -0.602848841 -0.684576244 FBgn0267153 CR45593 - http://flybase.org/reports/FBgn0267153 non_protein_coding_gene - - - CR45593 - CR45593 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026060 Mipp2 Multiple inositol polyphosphate phosphatase 2 http://flybase.org/reports/FBgn0026060 "FBgn0026701, FBgn0029065" protein_coding_gene bisphosphoglycerate 3-phosphatase activity ; GO:0034417 | inferred from sequence or structural similarity with HGNC:7102 inositol phosphate phosphatase activity ; GO:0052745 | inferred from biological aspect of ancestor with PANTHER:PTN000469221 acid phosphatase activity ; GO:0003993 | inferred from biological aspect of ancestor with PANTHER:PTN000469220 TOR signaling ; GO:0031929 | inferred from electronic annotation with InterPro:IPR004083 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:7102 TORC1 complex ; GO:0031931 | inferred from electronic annotation with InterPro:IPR004083 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:7102 "l(1)G0050, l(1)G0303, CG4317, Mipp2, mipp2" "IPR000560:Histidine phosphatase superfamily, clade-2, IPR016274:Histidine acid phosphatase, eukaryotic, IPR029033:Histidine phosphatase superfamily, IPR004083:Regulatory associated protein of TOR, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG4317 11-Aug-17 DroID_v2017_08 "Drer\minpp1b, Drer\minpp1a" "Scer\PHO12, Scer\DIA3, Scer\PHO5, Scer\PHO11, Scer\PHO3" - Xtro\minpp1 Mmus\Minpp1 Hsap\MINPP1 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable" "third instar larva,synapse,neuromuscular junction" FBgn0005277 M(1)k Minute (1) k http://flybase.org/reports/FBgn0005277 - gene - - - M(1)k - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040397 CG3655 - http://flybase.org/reports/FBgn0040397 protein_coding_gene - - - "EG:103E12.3, RE126B2, CG3655" IPR008166:Glycosyltransferase family 92 CG3655 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-56i24.1, Drer\si:ch73-211l2.1, Drer\zgc:194839, Drer\si:zfos-464b6.2" - "Cele\Y47D3B.4, Cele\F13G3.3, Cele\ZK488.6, Cele\C01G5.9, Cele\C14C6.8, Cele\Y105C5B.25, Cele\galt-1, Cele\ZK1025.4, Cele\C18G1.7, Cele\F18F11.4, Cele\K06H6.4, Cele\F49C12.5, Cele\C31B8.7, Cele\F28H7.7, Cele\T06A1.1, Cele\F36F12.3, Cele\C14C6.6, Cele\R08C7.4, Cele\T06A1.5, Cele\F46F5.7, Cele\ZK488.5, Cele\C49A1.5" "Xtro\LOC100495879, Xtro\LOC100492375, Xtro\LOC100145503" - - "viable,fertile" FBgn0030086 CCT2 Chaperonin containing TCP1 subunit 2 http://flybase.org/reports/FBgn0030086 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012716 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 neurogenesis ; GO:0022008 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000144135 cytoplasm ; GO:0005737 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG7033, SD02216p, CCT2, TCP-1beta, Cct2, Tcp1-beta, TCP1beta, Q8IRM8_DROME, Q9W392_DROME, TCP1-beta" "IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012716:T-complex protein 1, beta subunit, IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG7033 11-Aug-17 DroID_v2017_08 Drer\cct2 Scer\CCT2 "Cele\mrt-2, Cele\cct-2" Xtro\cct2 Mmus\Cct2 Hsap\CCT2 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell,neuroblast | larval stage" DRSC18415 E 0.182125564 -1.116146489 0.10599678 -2.029641783 -0.263740098 0.134988671 FBgn0030555 Fbxl4 F box and leucine-rich-repeat gene 4 http://flybase.org/reports/FBgn0030555 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from genetic interaction with Camta SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG1839, Fbxl4, dFbxl4, FBXL4" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR006553:Leucine-rich repeat, cysteine-containing subtype" CG1839 11-Aug-17 DroID_v2017_08 "Drer\zgc:158376, Drer\fbxl6, Drer\si:dkey-192l18.9, Drer\fbxl15, Drer\kdm2aa, Drer\kdm2ab, Drer\fbxl4, Drer\fbxl17" "Scer\GRR1, Scer\UBP8" "Cele\Y71A12B.12, Cele\duo-3" "Xtro\fbxl4, Xtro\fbxl19, Xtro\kdm2b, Xtro\fbxl12" "Mmus\Fbxl4, Mmus\Fbxl6, Mmus\Kdm2b, Mmus\Fbxl17, Mmus\Lrrc29, Mmus\Fbxl21, Mmus\Kdm2a, Mmus\Fbxl19" "Hsap\FBXL17, Hsap\FBXL6, Hsap\FBXL19, Hsap\FBXL4, Hsap\KDM2B, Hsap\KDM2A, Hsap\LRRC29" "viable,fertile" FBgn0041613 X-element\ORF1 X-element ORF1 http://flybase.org/reports/FBgn0041613 transposable_element_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 "transposition, DNA-mediated ; GO:0006313 | inferred from mutant phenotype" - X-element\ORF1 "IPR006579:Pre-C2HC domain, IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262369 mir-31b mir-31b stem loop http://flybase.org/reports/FBgn0262369 miRNA_gene - segmentation ; GO:0035282 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-31b, mir-31b, miR-31b, MIR-31, CR42882, miR-31, CR33568, dme-miR-31b" - CR42882 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal" "wing,wing margin bristle,wing vein L5,wing margin" FBgn0034968 RpL12 Ribosomal protein L12 http://flybase.org/reports/FBgn0034968 protein_coding_gene rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000184007 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000911, InterPro:IPR020783, InterPro:IPR020785 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000184007 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "CG3195, L12, anon-EST:Posey236, RpL12, Rpl12, Rp L12, Q9W1B9_DROME, RPL12" "IPR000911:Ribosomal protein L11/L12, IPR020783:Ribosomal protein L11, C-terminal, IPR020784:Ribosomal protein L11, N-terminal, IPR020785:Ribosomal protein L11, conserved site" CG3195 11-Aug-17 DroID_v2017_08 Drer\rpl12 "Scer\RPL12A, Scer\RPL12B" Cele\rpl-12 Xtro\rpl12 Mmus\Rpl12 Hsap\RPL12 "lethal,viable,developmental rate defective" DRSC04344 IE -2.554521324 -2.286701748 1.784145929 -4.843007321 0.689624812 1.196897334 FBgn0266717 Bruce BIR repeat containing ubiquitin-conjugating enzyme http://flybase.org/reports/FBgn0266717 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN000005165 ubiquitin conjugating enzyme activity ; GO:0061631 | inferred from direct assay regulation of cytokinesis ; GO:0032465 | inferred from electronic annotation with InterPro:IPR022103 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype programmed cell death ; GO:0012501 | inferred from genetic interaction with rpr inferred from genetic interaction with grim cellular response to starvation ; GO:0009267 | inferred from mutant phenotype regulation of signal transduction ; GO:0009966 | inferred from biological aspect of ancestor with PANTHER:PTN000005165 protein polyubiquitination ; GO:0000209 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from direct assay negative regulation of nurse cell apoptotic process ; GO:0045849 | inferred from mutant phenotype negative regulation of macroautophagy ; GO:0016242 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with MGI:MGI:1276108 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000005165 "dBruce, Bruce, mod86, dbruce, bruce, dBRUCE, CG6303, BRUCE" "IPR017986:WD40-repeat-containing domain, IPR000608:Ubiquitin-conjugating enzyme E2, IPR001370:BIR repeat, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR022103:Baculoviral IAP repeat-containing protein 6, IPR015943:WD40/YVTN repeat-like-containing domain" CG6303 11-Aug-17 DroID_v2017_08 "Drer\xiap, Drer\birc2, Drer\ube2o, Drer\birc5a, Drer\birc5b, Drer\birc6" - Cele\ubc-17 "Xtro\birc6, Xtro\xiap, Xtro\birc5.2, Xtro\birc2, Xtro\birc5.1, Xtro\birc7" "Mmus\Naip5, Mmus\Xiap, Mmus\Birc7, Mmus\Naip1, Mmus\Naip6, Mmus\Birc3, Mmus\Birc6, Mmus\Birc2, Mmus\Ube2o, Mmus\Birc5, Mmus\Naip2" "Hsap\BIRC6, Hsap\NAIP, Hsap\BIRC2, Hsap\BIRC5, Hsap\UBE2O, Hsap\BIRC7, Hsap\XIAP, Hsap\BIRC3, Hsap\BIRC8" FBgn0002885 mus111 mutagen-sensitive 111 http://flybase.org/reports/FBgn0002885 - gene - - - "mus(1)111, mus111" - - 11-Aug-17 DroID_v2017_08 - - - - - - "radiation sensitive,chemical sensitive,female sterile,recessive" FBgn0260780 wisp wispy http://flybase.org/reports/FBgn0260780 protein_coding_gene polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from sequence or structural similarity with WB:WBGene00001596 polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from direct assay polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from sequence or structural similarity with UniProtKB:Q6PIY7 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24433 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype pronuclear fusion ; GO:0007344 | inferred from mutant phenotype pronuclear migration ; GO:0035046 | inferred from mutant phenotype RNA polyadenylation ; GO:0043631 | inferred from sequence or structural similarity with UniProtKB:Q6PIY7 egg activation ; GO:0007343 | inferred from mutant phenotype sperm aster formation ; GO:0035044 | inferred from mutant phenotype regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype RNA polyadenylation ; GO:0043631 | inferred from direct assay spindle assembly involved in female meiosis ; GO:0007056 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype oocyte maturation ; GO:0001556 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "wisp, fs(1)M19, CG15737, DmCG15737, wispy, TAMP, Wisp" "IPR002058:PAP/25A-associated, IPR015943:WD40/YVTN repeat-like-containing domain" CG15737 11-Aug-17 DroID_v2017_08 "Drer\zcchc6, Drer\zcchc11, Drer\papd4, Drer\mtpap, Drer\tut1" - "Cele\pup-3, Cele\C53A5.16, Cele\usip-1, Cele\Y34F4.3, Cele\pup-2, Cele\F43H9.3, Cele\T08B2.4, Cele\F31C3.2, Cele\R07H5.11, Cele\F43E2.1, Cele\gld-2, Cele\mut-2, Cele\cid-1" "Xtro\mtpap, Xtro\zcchc11, Xtro\papd4, Xtro\tut1, Xtro\zcchc6" "Mmus\Papd4, Mmus\Zcchc11, Mmus\Zcchc6, Mmus\Mtpap, Mmus\Tut1" "Hsap\ZCCHC6, Hsap\PAPD4, Hsap\TUT1, Hsap\MTPAP, Hsap\ZCCHC11" FBgn0013470 l(1)10P11 lethal (1) 10P11 http://flybase.org/reports/FBgn0013470 - gene - - - l(1)10P11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect" "egg,germline clone,segment" FBgn0005703 l(1)TK106 lethal (1) TK106 http://flybase.org/reports/FBgn0005703 - gene - - - "l106, l(1)TK106" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye,lamina" FBgn0025927 l(1)43 lethal (1) 43 http://flybase.org/reports/FBgn0025927 - gene - - - "l-43, l(1)43" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024757 EC88 EC88 http://flybase.org/reports/FBgn0024757 - gene - - - EC88 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,female,non-enhancer of variegation,male" FBgn0051204 CG31204 - http://flybase.org/reports/FBgn0051204 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15569, BcDNA:AT25127, CG31204" - CG31204 11-Aug-17 DroID_v2017_08 "Drer\ugt2b6, Drer\ugt2b3, Drer\ugt1ab, Drer\ugt2a6, Drer\ugt8, Drer\ugt5b3, Drer\ugt5b2, Drer\ugt5g1, Drer\ugt2a5, Drer\zgc:172315, Drer\ugt5f1, Drer\ugt5a2, Drer\ugt5g2, Drer\ugt2a2, Drer\ugt5c2, Drer\ugt2b1, Drer\ugt5a1, Drer\ugt5d1, Drer\ugt5e1, Drer\ugt1b7, Drer\ugt5c3, Drer\ugt5c1, Drer\ugt5a5, Drer\ugt2b5" Scer\ATG26 - "Xtro\ugt1a6, Xtro\ugt2b4, Xtro\ugt2a1, Xtro\ugt8, Xtro\ugt3a2" "Mmus\Ugt2a1, Mmus\Ugt2b1, Mmus\Ugt2b34, Mmus\Ugt1a6b, Mmus\Ugt8a, Mmus\Ugt2b35, Mmus\Ugt2a3, Mmus\Ugt2b5, Mmus\Ugt2b37, Mmus\Ugt3a2, Mmus\Ugt2b36, Mmus\Ugt1a1, Mmus\Ugt3a1, Mmus\Ugt2b38" "Hsap\UGT2B15, Hsap\UGT1A1, Hsap\UGT8, Hsap\UGT2B10, Hsap\UGT3A2, Hsap\UGT1A3, Hsap\UGT2B11, Hsap\UGT2B28, Hsap\UGT2B7, Hsap\UGT2B17, Hsap\UGT2A3, Hsap\UGT3A1, Hsap\UGT2B4, Hsap\UGT2A2" viable FBgn0083296 E(smoDN)1875 Enhancer of smoDN 1875 http://flybase.org/reports/FBgn0083296 gene - - - E(smoDN)1875 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067369 l(2)NC192 lethal (2) NC192 http://flybase.org/reports/FBgn0067369 gene - - - "NC192, l(2)NC192" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011884 tRNA:Ile-AAT-1-6 transfer RNA:Isoleucine-AAT 1-6 http://flybase.org/reports/FBgn0011884 "FBgn0003788, FBgn0050246, FBgn0060197" tRNA_gene AUU codon-amino acid adaptor activity ; GO:0033433 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033433 cytosol ; GO:0005829 | inferred by curator from GO:0033433 "CR30246, ile-d, AE002787.trna39-IleAAT, tRNA:I:AAT:AE002787-e, tRNA:ile:49Fd, tRNA[Ile], chr2R.trna21-IleAAT, tRNA-Ile[AAU], tRNA-Ile-AAT-1-6, tRNA:Ile-AAT-1-6, tRNA:I:49Fd, AUU" - CR30246 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036952 CG6933 - http://flybase.org/reports/FBgn0036952 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG6933 IPR002557:Chitin binding domain CG6933 11-Aug-17 DroID_v2017_08 Drer\thbd - "Cele\R02F2.4, Cele\dct-9" - - Hsap\MATN2 "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0086063 snoRNA:Me28S-C788a - http://flybase.org/reports/FBgn0086063 snoRNA_gene - - - "snoRNA:Me28S-C788a, Me28S-Cm788a, Me28S-C788a(DmSnR58), CR34692, DmSnR58a" - CR34692 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065318 l(2)SH1923 lethal (2) SH1923 http://flybase.org/reports/FBgn0065318 gene - - - "l(2)SH1923, l(2)SH2 1923" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052259 CG32259 - http://flybase.org/reports/FBgn0052259 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs27e11, CG32259" - CG32259 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266764 CR45229 - http://flybase.org/reports/FBgn0266764 non_protein_coding_gene - - - CR45229 - CR45229 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010027 E(Dl)F167 Enhancer of Delta F167 http://flybase.org/reports/FBgn0010027 - gene - - - E(Dl)F167 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028222 l(3)S007403a lethal (3) S007403a http://flybase.org/reports/FBgn0028222 gene - - - "0074/03, l(3)S007403, l(3)S007403a, l(3)s007403" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0030116 CR17438 - http://flybase.org/reports/FBgn0030116 pseudogene_attribute - - - "CG17438, CR17438" - CR17438 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266731 CR45204 - http://flybase.org/reports/FBgn0266731 non_protein_coding_gene - - - CR45204 - CR45204 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016802 l(1)K4 lethal (1) K4 http://flybase.org/reports/FBgn0016802 - gene - - - "l(1)K4, K4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263502 CR43491 - http://flybase.org/reports/FBgn0263502 non_protein_coding_gene - - - CR43491 - CR43491 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265845 CR44634 - http://flybase.org/reports/FBgn0265845 non_protein_coding_gene - - - CR44634 - CR44634 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011819 Orf5C Orf5C http://flybase.org/reports/FBgn0011819 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-5C, Orf5C" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266132 c65 - http://flybase.org/reports/FBgn0266132 gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - c65 - - 11-Aug-17 DroID_v2017_08 - - - - - - gravitaxis defective FBgn0035251 Vta1 Vesicle trafficking 1 http://flybase.org/reports/FBgn0035251 protein_coding_gene ATPase activator activity ; GO:0001671 | inferred from sequence or structural similarity with SGD:S000004171 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from sequence or structural similarity with SGD:S000004171 Vps4-Vta1 complex ; GO:1990621 | inferred from sequence or structural similarity with SGD:S000004171 multivesicular body ; GO:0005771 | inferred from sequence or structural similarity with SGD:S000004171 "CG7967, Vta1" "IPR023175:Vacuolar protein sorting-associate protein Vta1/Callose synthase, N-terminal domain" CG7967 11-Aug-17 DroID_v2017_08 Drer\vta1 Scer\VTA1 Cele\T23G11.7 Xtro\vta1 Mmus\Vta1 Hsap\VTA1 FBgn0035688 CG10289 - http://flybase.org/reports/FBgn0035688 protein_coding_gene - - - "CG10289, PpV[[R]]" IPR007587:SIT4 phosphatase-associated protein family CG10289 11-Aug-17 DroID_v2017_08 "Drer\ppp6r3, Drer\ppp6r2b, Drer\ppp6r2a" "Scer\SAP155, Scer\SAP190, Scer\SAP185, Scer\SAP4" Cele\saps-1 "Xtro\ppp6r2, Xtro\ppp6r1, Xtro\ppp6r3" "Mmus\Ppp6r2, Mmus\Ppp6r1, Mmus\Ppp6r3" "Hsap\PPP6R2, Hsap\PPP6R3, Hsap\PPP6R1" "partially lethal - majority die,some die during pupal stage" FBgn0013279 Hsp70Bc Heat-shock-protein-70Bc http://flybase.org/reports/FBgn0013279 "FBgn0001232, FBgn0038059" protein_coding_gene - response to heat ; GO:0009408 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype response to unfolded protein ; GO:0006986 | non-traceable author statement response to heat ; GO:0009408 | non-traceable author statement heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from mutant phenotype response to toxic substance ; GO:0009636 | inferred from expression pattern microtubule associated complex ; GO:0005875 | inferred from direct assay "Hsp70, hsp70, HSP70, hsp70B, CG6489, hsp70Bc, Hsp70Bd, Hsp70B, Hsp70Bbc, Hsp 70, Hsp70A7d, dhsp70, Hsp70(87C), hsp-70, hsp70 87C, Hsp70Bc, Hsp70-BC, Hsp-70, dHsp70, Dm-hsp70, HSP70Bc, Hsp-70Bc, Bc, Hsp70bc" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG6489 11-Aug-17 DroID_v2017_08 "Drer\hsc70, Drer\hspa5, Drer\hspa12b, Drer\hspa14, Drer\hsp70.2, Drer\hsp70.1, Drer\hsp70l, Drer\hspa8, Drer\hspa13, Drer\si:dkey-4p15.3, Drer\nckap1, Drer\hspa12a, Drer\si:ch211-199o1.2" "Scer\SSB2, Scer\SSB1, Scer\SSA4, Scer\SSQ1, Scer\SSA1, Scer\SSA3, Scer\SSZ1, Scer\SSA2, Scer\KAR2, Scer\ECM10" "Cele\F44E5.5, Cele\F11F1.1, Cele\hsp-1, Cele\hsp-3, Cele\hsp-4, Cele\hsp-70, Cele\gex-3, Cele\F44E5.4" "Xtro\hsp70, Xtro\hspa8, Xtro\hspa14, Xtro\hspa13, Xtro\nckap1, Xtro\hspa1b, Xtro\hspa1l, Xtro\hspa1a, Xtro\hspa12b, Xtro\hspa2, Xtro\nckap1l, Xtro\hspa5" "Mmus\Hspa8, Mmus\Hspa12b, Mmus\Hspa1l, Mmus\Nckap1l, Mmus\Hspa1b, Mmus\Nckap1, Mmus\Hspa2, Mmus\Hspa5, Mmus\Hspa14, Mmus\Hspa12a, Mmus\Hspa13, Mmus\Hspa1a" "Hsap\HSPA12B, Hsap\HSPA1L, Hsap\NCKAP1, Hsap\HSPA6, Hsap\HSPA5, Hsap\HSPA13, Hsap\NCKAP1L, Hsap\HSPA14, Hsap\HSPA2, Hsap\HSPA8, Hsap\HSPA12A, Hsap\HSPA1B, Hsap\HSPA1A" "aging defective,male limited,heat sensitive" DRSC16053 E -0.484495433 -1.336312072 -4.955363662 -2.221734912 0.00255059 0.957092036 FBgn0005078 fs(2)OW802 female sterile (2) OW802 http://flybase.org/reports/FBgn0005078 - gene - - - fs(2)OW802 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040272 Su(Rex) Su(Rex) http://flybase.org/reports/FBgn0040272 gene - - - Su(Rex) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267684 CR46020 - http://flybase.org/reports/FBgn0267684 non_protein_coding_gene - - - CR46020 - CR46020 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065143 l(3)SH094 lethal (3) SH094 http://flybase.org/reports/FBgn0065143 gene - - - "l(3)SH094, l(2)SH3 094" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086078 snoRNA:Me28S-A774b - http://flybase.org/reports/FBgn0086078 snoRNA_gene - - - "snoRNA:Me28S-A774b, Me28S-Am774b, CR34707, DmU18b" - CR34707 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259444 EP-36 - http://flybase.org/reports/FBgn0259444 gene - - - EP-36 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing" FBgn0033010 Atf6 Atf6 http://flybase.org/reports/FBgn0033010 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR004827 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR004827" - "Atf6, CG3136, ATF6, atf6, DM15" IPR004827:Basic-leucine zipper domain CG3136 11-Aug-17 DroID_v2017_08 "Drer\atf6, Drer\atf6b" - Cele\atf-6 "Xtro\atf6, Xtro\atf6b" "Mmus\Atf6b, Mmus\Atf6" "Hsap\ATF6, Hsap\ATF6B" "viable,fertile" DRSC19797 I 1.943321295 0.336647229 -0.058478207 0.345330912 -0.260409425 -0.10536524 FBgn0001923 l(2)25Cd lethal (2) 25Cd http://flybase.org/reports/FBgn0001923 - gene - - - "jf18, l(2)jf18, l(2)25Cd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0011576 Cyp4d2 Cytochrome P450-4d2 http://flybase.org/reports/FBgn0011576 "FBgn0010219, FBgn0010384" protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4d2, EG:152A3.4, CG3466, CYP4D2, P450, P-450, Cyt-P450-4D2, Cyp4d2, Cyp4D2" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG3466 11-Aug-17 DroID_v2017_08 "Drer\cyp46a1.1, Drer\cyp46a1.2, Drer\cyp3a65, Drer\cyp3c2, Drer\cyp20a1, Drer\cyp3c4, Drer\cyp19a1a, Drer\cyp4t8, Drer\cyp46a1.4, Drer\LOC100329425, Drer\cyp46a1.3, Drer\cyp26b1, Drer\cyp19a1b, Drer\cyp4f3, Drer\cyp26a1, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp26c1" "Scer\DIT2, Scer\ERG5" "Cele\cyp-31A3, Cele\cyp-31A5, Cele\cyp-13A1, Cele\cyp-25A1, Cele\cyp-25A4, Cele\cyp-13A8, Cele\cyp-25A3, Cele\cyp-13A12, Cele\cyp-42A1, Cele\cyp-13A4, Cele\cyp-32A1, Cele\cyp-37A1, Cele\cyp-37B1, Cele\cyp-29A4, Cele\cyp-13A11, Cele\cyp-13A5, Cele\cyp-32B1, Cele\cyp-31A2, Cele\cyp-13A10, Cele\cyp-13A3, Cele\cyp-13A7, Cele\cyp-23A1, Cele\cyp-29A2, Cele\cyp-25A2, Cele\cyp-29A3" "Xtro\cyp4b1.2, Xtro\LOC100488227, Xtro\mgc108213, Xtro\cyp4b1, Xtro\cyp4f22, Xtro\cyp26a1, Xtro\LOC100487918, Xtro\cyp26c1, Xtro\cyp19a1, Xtro\cyp4f2, Xtro\cyp20a1, Xtro\cyp26b1, Xtro\cyp4v2" "Mmus\Cyp4f14, Mmus\Cyp4a14, Mmus\Cyp19a1, Mmus\Cyp4f17, Mmus\Cyp4f18, Mmus\Cyp4f16, Mmus\Cyp4f13, Mmus\Cyp4a12a, Mmus\Cyp3a44, Mmus\Cyp4x1, Mmus\Cyp4a32, Mmus\Cyp3a25, Mmus\Cyp3a41a, Mmus\Cyp4a31, Mmus\Cyp3a57, Mmus\Cyp4b1, Mmus\Cyp4f37, Mmus\Cyp4f15, Mmus\Cyp3a16, Mmus\Cyp20a1, Mmus\Cyp3a11, Mmus\Cyp4a30b, Mmus\Cyp4a29, Mmus\Cyp3a13, Mmus\Cyp4a10, Mmus\Cyp3a41b, Mmus\Cyp4f40, Mmus\Cyp4a12b, Mmus\Cyp46a1, Mmus\Cyp4v3, Mmus\Cyp26c1, Mmus\Cyp4f39, Mmus\Cyp26a1, Mmus\Cyp3a59, Mmus\Cyp26b1" "Hsap\CYP3A4, Hsap\CYP4F8, Hsap\CYP4F3, Hsap\CYP26C1, Hsap\CYP4F22, Hsap\CYP4Z1, Hsap\CYP26B1, Hsap\CYP4A22, Hsap\CYP4F12, Hsap\CYP4V2, Hsap\CYP20A1, Hsap\CYP3A5, Hsap\CYP19A1, Hsap\CYP4F2, Hsap\CYP3A7, Hsap\CYP4F11, Hsap\CYP26A1, Hsap\CYP4A11, Hsap\CYP4B1, Hsap\CYP4X1, Hsap\CYP3A43, Hsap\CYP46A1" viable FBgn0033742 CG8550 - http://flybase.org/reports/FBgn0033742 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG8550 "IPR000718:Peptidase M13, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG8550 11-Aug-17 DroID_v2017_08 "Drer\phex, Drer\mmel1, Drer\ece1, Drer\ece2b" - "Cele\nep-24, Cele\nep-3, Cele\nep-9, Cele\nep-21, Cele\nep-17, Cele\nep-16, Cele\nep-8, Cele\nep-7, Cele\nep-13, Cele\nep-19, Cele\nep-23, Cele\nep-26, Cele\nep-18, Cele\nep-12, Cele\nep-20, Cele\nep-6, Cele\nep-5, Cele\nep-10" "Xtro\ecel1, Xtro\ece1, Xtro\mmel1, Xtro\ece2" "Mmus\Kel, Mmus\Mmel1, Mmus\Ecel1, Mmus\Ece2, Mmus\Ece1, Mmus\Mme, Mmus\Phex" "Hsap\KEL, Hsap\MME, Hsap\ECEL1, Hsap\MMEL1, Hsap\ECE2, Hsap\PHEX, Hsap\ECE1" "fertile,viable" FBgn0038814 CG15923 - http://flybase.org/reports/FBgn0038814 protein_coding_gene - negative regulation of centrosome duplication ; GO:0010826 | inferred from electronic annotation with InterPro:IPR019170 cilium assembly ; GO:0060271 | inferred from electronic annotation with InterPro:IPR019170 regulation of cell cycle ; GO:0051726 | inferred from direct assay MKS complex ; GO:0036038 | inferred from electronic annotation with InterPro:IPR019170 CG15923 IPR019170:Meckelin CG15923 11-Aug-17 DroID_v2017_08 Drer\tmem67 - Cele\mks-3 Xtro\tmem67 Mmus\Tmem67 Hsap\TMEM67 partially lethal - majority die FBgn0051950 CG31950 - http://flybase.org/reports/FBgn0051950 protein_coding_gene - - NatC complex ; GO:0031417 | inferred from electronic annotation with InterPro:IPR034110 CG31950 "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR034110:LSM domain containing 1" CG31950 11-Aug-17 DroID_v2017_08 Drer\naa38 Scer\SMB1 Cele\Y48G1C.9 Xtro\naa38 Mmus\Naa38 Hsap\NAA38 viable DRSC00160 I 1.576241843 -0.194312383 0.031320643 -0.919928899 -0.698711682 -1.256418018 FBgn0022737 en::sr en::sr http://flybase.org/reports/FBgn0022737 - engineered_fusion_gene - - - en::sr - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval somatic muscle,muscle fiber | embryonic stage,ventral oblique muscle | embryonic stage" FBgn0065292 l(2)SH2004 lethal (2) SH2004 http://flybase.org/reports/FBgn0065292 gene - - - "l(2)SH2004, l(2)SH2 2004" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260079 2L4508 - http://flybase.org/reports/FBgn0260079 gene - - - 2L4508 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0022328 l(1)A13.3 lethal (1) A13.3 http://flybase.org/reports/FBgn0022328 - gene - - - "A13.3, l(1)A13.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001546 l(1)15Ba lethal (1) 15Ba http://flybase.org/reports/FBgn0001546 - gene - - - "l(1)g27a, l(1)15Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085415 CG34386 - http://flybase.org/reports/FBgn0085415 protein_coding_gene - - - "CG34386, CG14496, CG14497" IPR015943:WD40/YVTN repeat-like-containing domain CG34386 11-Aug-17 DroID_v2017_08 - - Cele\K01A11.1 - - - "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0035563 CG13716 - http://flybase.org/reports/FBgn0035563 protein_coding_gene - regulation of localization ; GO:0032879 | inferred from sequence or structural similarity with halo - "HL1, CG13716" IPR007970:Protein of unknown function DUF733 CG13716 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005163 l(2)G341 lethal (2) G341 http://flybase.org/reports/FBgn0005163 - gene - - - l(2)G341 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264370 CR43822 - http://flybase.org/reports/FBgn0264370 non_protein_coding_gene - - - CR43822 - CR43822 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002547 lfl little fly-like http://flybase.org/reports/FBgn0002547 FBgn0011265 gene - - - "B-96, B-56, l(1)B56, J22, 13, 11, 10, l(1)HM46, l(1)19Fa, lfl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,male,visible,cell lethal,germline clone,viable,reduced,lethal - all die before end of larval stage,some die during larval stage" "adult thorax & microchaeta,adult thorax & macrochaeta,head bristle,eye,wing,posterior crossvein,ocellar bristle,postvertical bristle,humeral bristle" FBgn0051898 CG31898 - http://flybase.org/reports/FBgn0051898 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:LD28680, CG31898" - CG31898 11-Aug-17 DroID_v2017_08 - - - - Mmus\Fam104a Hsap\FAM104A "viable,fertile" FBgn0264742 CG44000 - http://flybase.org/reports/FBgn0264742 protein_coding_gene - - - "CG44000, Dromel_CG31919_FBtr0079006_mORF, CG31919, CG5822" - CG44000 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021954 l(2)k10239 lethal (2) k10239 http://flybase.org/reports/FBgn0021954 - gene - - - l(2)k10239 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025626 CG4281 - http://flybase.org/reports/FBgn0025626 - protein_coding_gene - - - "EG:22E5.7, CG4281" IPR026291:G patch domain-containing protein 2 CG4281 11-Aug-17 DroID_v2017_08 Drer\gpatch2 - - - "Mmus\Gpatch2l, Mmus\Gpatch2" "Hsap\GPATCH2, Hsap\GPATCH2L" "lethal,recessive,viable,visible" trichogen cell FBgn0053772 CG33772 - http://flybase.org/reports/FBgn0053772 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1031, CG33772" IPR010512:Protein of unknown function DUF1091 CG33772 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036959 CG6951 - http://flybase.org/reports/FBgn0036959 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR016192 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002125, InterPro:IPR016192" - - "anon-WO0118547.579, CG6951" "IPR002125:Cytidine and deoxycytidylate deaminases, zinc-binding, IPR015517:Deoxycytidylate deaminase-related, IPR016192:APOBEC/CMP deaminase, zinc-binding, IPR016193:Cytidine deaminase-like" CG6951 11-Aug-17 DroID_v2017_08 "Drer\cdadc1, Drer\dctd" Scer\DCD1 Cele\ZK643.2 "Xtro\dctd, Xtro\cdadc1" "Mmus\Cdadc1, Mmus\Dctd" "Hsap\DCTD, Hsap\CDADC1" viable FBgn0024763 EC33 EC33 http://flybase.org/reports/FBgn0024763 - gene - - - EC33 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,non-enhancer of variegation" FBgn0032957 CG2225 - http://flybase.org/reports/FBgn0032957 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2225 - CG2225 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0005491 l(1)ts2641 lethal (1) ts2641 http://flybase.org/reports/FBgn0005491 - gene - - - l(1)ts2641 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0010294 ng2 new glue 2 http://flybase.org/reports/FBgn0010294 FBgn0063074 protein_coding_gene - - - "ng-2, ng, EG:96G10.4, CG14266, BcDNA:RE05239, ng2" - CG14266 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005602 yemG3c yema gene 3c http://flybase.org/reports/FBgn0005602 FBgn0004042 gene - - - "yG3c/0.7, yG3c, yG0.7, yT3c, yT0.7, yemG3c" - - 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage--adult stage , adult stage && oogenesis stage , embryonic stage | stage <= 8 , embryonic stage , embryonic stage | 12-18 hr , embryonic stage | stage <=8 , embryonic stage--larval stage , embryonic stage -- adult stage , larval stage--pupal stage , larval stage , pupal stage " " spermatocyte

, ovary

, organism

, lymph gland | restricted

, central nervous system | restricted

, imaginal disc

, hindgut

" FBgn0260655 l(3)76BDm lethal (3) 76BDm http://flybase.org/reports/FBgn0260655 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein localization to pre-autophagosomal structure ; GO:0034497 | inferred from biological aspect of ancestor with PANTHER:PTN000312051 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000002515 nucleophagy ; GO:0044804 | inferred from biological aspect of ancestor with PANTHER:PTN000312051 pexophagy ; GO:0030242 | inferred from biological aspect of ancestor with PANTHER:PTN000312051 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000312051 TRAPPIII protein complex ; GO:1990072 | inferred from biological aspect of ancestor with PANTHER:PTN000312051 pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN000312051 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000002515 cytoplasmic vesicle ; GO:0031410 | inferred from biological aspect of ancestor with PANTHER:PTN000312051 "CG8793, l(3)76BDm, l(3)L3809" "IPR011990:Tetratricopeptide-like helical domain, IPR013935:TRAPP II complex, Trs120, IPR024420:TRAPP III complex, Trs85, IPR013783:Immunoglobulin-like fold" CG8793 11-Aug-17 DroID_v2017_08 Drer\trappc8 Scer\TRS85 Cele\trpp-8 Xtro\trappc8 Mmus\Trappc8 Hsap\TRAPPC8 FBgn0263383 CR43435 - http://flybase.org/reports/FBgn0263383 non_protein_coding_gene - - - CR43435 - CR43435 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010844 l(3)04629 lethal (3) 04629 http://flybase.org/reports/FBgn0010844 - gene - - - "6/24, 0006/24, l(3)04629" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0060656 l(3)S082901 lethal (3) S082901 http://flybase.org/reports/FBgn0060656 gene - - - "0829/01, l(3)S082901" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0010424 TpnC73F Troponin C at 73F http://flybase.org/reports/FBgn0010424 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "TnC, DmTpnCIa, DmTpnC73F, TpnC Ia, TNC, DmTnC3, CG7930, TnC73F, TpnC73F, tpnC73F, TpnCIa, TNC73F, Tnc2" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG7930 11-Aug-17 DroID_v2017_08 "Drer\efcab6, Drer\calb2a, Drer\calb2b, Drer\cabp4, Drer\calm2a, Drer\cabp1a, Drer\efcab11, Drer\si:ch211-197n1.2, Drer\caln1, Drer\calm1a, Drer\pvalb2, Drer\calb1, Drer\calm3a, Drer\cabp5b, Drer\caln2, Drer\cabp1b, Drer\cabp2b, Drer\scgn, Drer\pvalb3, Drer\calml4a, Drer\pvalb1, Drer\calm1b, Drer\calm3b, Drer\rhbdl3, Drer\cabp5a, Drer\calml4b, Drer\calm2b, Drer\cabp2a, Drer\pvalb4, Drer\efcab2, Drer\pvalb9, Drer\cabp7b, Drer\tnnc1a, Drer\pvalb8, Drer\pvalb6, Drer\tnnc1b, Drer\tnnc2" "Scer\CDC31, Scer\MLC2, Scer\MLC1, Scer\CMD1" "Cele\tnc-2, Cele\cmd-1, Cele\cal-3, Cele\pat-10, Cele\cal-4, Cele\cal-1, Cele\cal-2" "Xtro\calm1, Xtro\pvalb.2, Xtro\LOC548651, Xtro\ocm.2, Xtro\calm2, Xtro\ocm, Xtro\scgn, Xtro\pvalb, Xtro\calb1, Xtro\efcab6, Xtro\calml4, Xtro\tnnc2, Xtro\pgm1, Xtro\cabp4, Xtro\cabp7, Xtro\tnnc1, Xtro\pvalb.1" "Mmus\Efcab6, Mmus\Calml4, Mmus\1700023F06Rik, Mmus\Efcab11, Mmus\Calm2, Mmus\Ocm, Mmus\Calb1, Mmus\Cabp7, Mmus\Efcab2, Mmus\Calm4, Mmus\Rhbdl3, Mmus\Spata21, Mmus\Pvalb, Mmus\Calb2, Mmus\Calm5, Mmus\Cabp5, Mmus\Calm1, Mmus\Tnnc1, Mmus\Cabp4, Mmus\Calml3, Mmus\Efcab7, Mmus\Cabp2, Mmus\Efcab9, Mmus\Efcab3, Mmus\Scgn, Mmus\Calm3, Mmus\Caln1, Mmus\Tnnc2, Mmus\Cabp1" "Hsap\TNNC1, Hsap\CALB1, Hsap\TNNC2, Hsap\EFCAB13, Hsap\CABP2, Hsap\CALML6, Hsap\CABP1, Hsap\CABP4, Hsap\EFCAB7, Hsap\EFCAB3, Hsap\EFCAB2, Hsap\CABP5, Hsap\EFCAB6, Hsap\CALM3, Hsap\CALML3, Hsap\CALML4, Hsap\SCGN, Hsap\CALM2, Hsap\PVALB, Hsap\CALB2, Hsap\CALN1, Hsap\CALM1, Hsap\RHBDL3, Hsap\EFCAB11, Hsap\EFCAB9, Hsap\CABP7, Hsap\SPATA21, Hsap\CALML5, Hsap\OCM, Hsap\OCM2" " larval stage , pupal stage , embryonic stage | late , embryonic stage -- adult stage " organism

"lethal,viable" FBgn0259365 C327.2 - http://flybase.org/reports/FBgn0259365 gene - - - C327.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing margin" FBgn0027561 CG18659 - http://flybase.org/reports/FBgn0027561 "FBgn0042194, FBgn0050347, FBgn0050348, FBgn0062216, FBgn0062219" protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence or structural similarity with HGNC:29324 endocytosis ; GO:0006897 | inferred from sequence or structural similarity with HGNC:29324 regulation of Rab protein signal transduction ; GO:0032483 | inferred from sequence or structural similarity with HGNC:29324 clathrin-coated vesicle ; GO:0030136 | inferred from sequence or structural similarity with HGNC:29324 "BcDNA:GH08789, CG8059, CG30348, CG30347, anon-WO0118547.145, anon-WO0118547.140, CG18659" "IPR001194:DENN domain, IPR005112:dDENN domain, IPR005113:uDENN domain" CG18659 11-Aug-17 DroID_v2017_08 "Drer\st5, Drer\dennd1b, Drer\dennd1a, Drer\dennd2da, Drer\dennd2c, Drer\si:dkey-76b14.2" - Cele\rme-4 "Xtro\dennd1a, Xtro\dennd2c, Xtro\dennd2d" "Mmus\Dennd1c, Mmus\St5, Mmus\Dennd2c, Mmus\Dennd1a, Mmus\Dennd1b, Mmus\Dennd2d, Mmus\Dennd2a" "Hsap\DENND2C, Hsap\SBF1, Hsap\DENND2D, Hsap\DENND1B, Hsap\ST5, Hsap\DENND1C, Hsap\DENND1A, Hsap\DENND2A" FBgn0034416 CG15109 - http://flybase.org/reports/FBgn0034416 protein_coding_gene - - - CG15109 - CG15109 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039257 tnc tenectin http://flybase.org/reports/FBgn0039257 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model epithelial tube morphogenesis ; GO:0060562 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype embryonic hindgut morphogenesis ; GO:0048619 | inferred from mutant phenotype imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype regulation of tube diameter ; GO:0035296 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from direct assay "CG13648, tnc, Mur96B, Tnc" IPR001007:VWFC domain CG13648 11-Aug-17 DroID_v2017_08 "Drer\scaf11, Drer\map6a, Drer\rtn4b, Drer\map6b, Drer\scaf1, Drer\phrf1, Drer\akap12b, Drer\rtn1b, Drer\ehbp1l1b" Scer\BMT6 - "Xtro\map6, Xtro\cep170" "Mmus\Rtn4, Mmus\Gprin1, Mmus\Map2, Mmus\Akap12, Mmus\Map6, Mmus\Rtn1, Mmus\Cep170, Mmus\Cmya5, Mmus\Scaf11, Mmus\Rtn3, Mmus\Phrf1, Mmus\Scaf1, Mmus\Ehbp1l1" "Hsap\RTN3, Hsap\AKAP12, Hsap\GPRIN1, Hsap\MAP2, Hsap\SCAF11, Hsap\EHBP1L1, Hsap\PHRF1, Hsap\CEP170, Hsap\MAP6, Hsap\SCAF1, Hsap\RTN4" "viable,lethal,visible" "embryonic/larval hindgut,embryonic large intestine,embryonic small intestine,embryonic/larval dorsal trunk,male genitalia,wing,wing margin,embryonic/larval salivary gland,embryonic Malpighian tubule,primary trachea,mesothoracic tergum" FBgn0069093 p170 p170 http://flybase.org/reports/FBgn0069093 gene - - - p170 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267106 CG45546 - http://flybase.org/reports/FBgn0267106 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45546 "IPR002919:Trypsin Inhibitor-like, cysteine rich domain" CG45546 11-Aug-17 DroID_v2017_08 - - "Cele\Y69H2.10, Cele\F36H9.4, Cele\C25E10.10, Cele\F47G3.4" - - - FBgn0027166 l(2)K2 lethal (2) K2 http://flybase.org/reports/FBgn0027166 - gene - - - l(2)K2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0041156 exex extra-extra http://flybase.org/reports/FBgn0041156 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000677913" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000677913 central nervous system development ; GO:0007417 | inferred from mutant phenotype nervous system development ; GO:0007399 | traceable author statement neuroendocrine cell differentiation ; GO:0061101 | inferred from mutant phenotype axon target recognition ; GO:0007412 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000677913 "Hb9, hb9, CG8254, HB9, dHb9, DHB9, exex, dhb9" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG8254 11-Aug-17 DroID_v2017_08 "Drer\hoxd4a, Drer\meox1, Drer\gbx1, Drer\hoxc8a, Drer\ved, Drer\hoxc1a, Drer\gbx2, Drer\hoxb7a, Drer\hoxc6a, Drer\pdx1, Drer\hoxb3a, Drer\hoxb6b, Drer\hoxa1a, Drer\hoxc6b, Drer\hoxc4a, Drer\hoxb5b, Drer\hoxb4a, Drer\hoxb8b, Drer\hoxc3a, Drer\hoxd3a, Drer\mnx1, Drer\hoxa3a, Drer\hoxb1b, Drer\gsx2, Drer\hoxb6a, Drer\mnx2a, Drer\hoxc5a, Drer\mnx2b, Drer\hoxa4a, Drer\hoxa9b, Drer\hoxa2b, Drer\meox2b, Drer\hoxa5a, Drer\hoxb1a, Drer\meox2a, Drer\gsx1, Drer\hoxb5a, Drer\hoxb2a" - "Cele\ceh-12, Cele\ceh-23, Cele\ceh-1" "Xtro\hoxb3, Xtro\hoxb4, Xtro\hoxb8, Xtro\hoxa3, Xtro\gbx2.1, Xtro\hoxd8, Xtro\hoxb1, Xtro\pdx1, Xtro\hoxb7, Xtro\hoxd1, Xtro\hoxc5, Xtro\hoxb5, Xtro\mnx1, Xtro\gsx2, Xtro\hoxc4, Xtro\gsx1, Xtro\hoxc3, Xtro\hoxd3, Xtro\hoxa2, Xtro\hoxb6, Xtro\hoxa5, Xtro\hoxb2, Xtro\gbx2.2, Xtro\hoxa1, Xtro\hoxc8, Xtro\meox2" "Mmus\Hoxa4, Mmus\Hoxb1, Mmus\Hoxa1, Mmus\Pdx1, Mmus\Hoxd1, Mmus\Hoxd4, Mmus\Hoxa6, Mmus\Hoxb3, Mmus\Hoxa3, Mmus\Hoxa7, Mmus\Hoxb8, Mmus\Hoxb4, Mmus\Hoxb5, Mmus\Hoxa2, Mmus\Gbx2, Mmus\Meox1, Mmus\Mnx1, Mmus\Gsx1, Mmus\Meox2, Mmus\Gsx2, Mmus\Gbx1, Mmus\Hoxc6, Mmus\Hoxd3, Mmus\Hoxd8, Mmus\Hoxb2, Mmus\Hoxb7, Mmus\Hoxc8, Mmus\Hoxa5, Mmus\Hoxc5, Mmus\Hoxc4, Mmus\Hoxb6" "Hsap\HOXA4, Hsap\HOXC8, Hsap\GSX1, Hsap\HOXD3, Hsap\MNX1, Hsap\HOXB3, Hsap\HOXA2, Hsap\GBX1, Hsap\HOXA6, Hsap\HOXA7, Hsap\HOXC6, Hsap\HOXB7, Hsap\HOXC5, Hsap\HOXA3, Hsap\HOXB1, Hsap\HOXA1, Hsap\HOXD1, Hsap\HOXB4, Hsap\GSX2, Hsap\HOXB6, Hsap\PDX1, Hsap\HOXB5, Hsap\MEOX1, Hsap\GBX2, Hsap\MEOX2, Hsap\HOXC4, Hsap\HOXD4, Hsap\HOXD8, Hsap\HOXB8, Hsap\HOXA5, Hsap\HOXB2" "neuroanatomy defective,viable,visible" "intersegmental nerve branch ISNb of A1-7,transverse nerve,embryonic ventral nervous system & neuron,intersegmental nerve,RP1 motor neuron,RP3 motor neuron,RP4 motor neuron,RP5 motor neuron,axon | embryonic stage,growth cone | embryonic stage,EW1 neuron,EW2 neuron,EW3 neuron,neuromuscular junction | embryonic stage,neuron,lateral,presumptive embryonic/larval central nervous system,abdominal segmental nerve | embryonic stage,intersegmental nerve | embryonic stage,longitudinal connective | embryonic stage,chaeta,supernumerary" FBgn0262755 Mst77Y-6Psi Male-specific pseudogene 77Y 6 http://flybase.org/reports/FBgn0262755 pseudogene_attribute - - - "Mst77Y-6Psi, Mst77Y-6aPsi" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011649 Mads-1 Mads-1 http://flybase.org/reports/FBgn0011649 - gene - - - Mads-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266406 CR45046 - http://flybase.org/reports/FBgn0266406 non_protein_coding_gene - - - CR45046 - CR45046 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014100 anon-44DE anon-44DE http://flybase.org/reports/FBgn0014100 - gene - - - anon-44DE - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001938 l(2)25Fd lethal (2) 25Fd http://flybase.org/reports/FBgn0001938 - gene - - - "l(2)gdh-16, l(2)25Fd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044379 anon-AE003450.1 anon-AE003450.1 http://flybase.org/reports/FBgn0044379 gene - - - anon-AE003450.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033192 Corin Corin http://flybase.org/reports/FBgn0033192 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001190 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001190, InterPro:IPR017448" "CG2105, SP75, Corin, corin" "IPR001190:SRCR domain, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR017448:SRCR-like domain, IPR020067:Frizzled domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR033116:Serine proteases, trypsin family, serine active site" CG2105 11-Aug-17 DroID_v2017_08 "Drer\fzd7a, Drer\fzd9a, Drer\fzd9b, Drer\LOC100331291, Drer\fzd7b, Drer\fzd10, Drer\corin, Drer\zgc:154142, Drer\tmprss5, Drer\sfrp2l, Drer\fzd3b, Drer\sfrp1a, Drer\loxl2a, Drer\masp2, Drer\fzd8b, Drer\fzd8a, Drer\tmprss4b, Drer\si:cabz01033205.3, Drer\plg, Drer\fzd2, Drer\smo, Drer\pik3ip1, Drer\fzd5, Drer\frzb, Drer\sfrp1b, Drer\sfrp2, Drer\sfrp5, Drer\si:dkey-33i11.3, Drer\fzd3a, Drer\szl, Drer\LOC101884738, Drer\si:dkey-14d8.21, Drer\si:dkey-14d8.20" - - "Xtro\mfrp, Xtro\fzd2, Xtro\sfrp1, Xtro\corin, Xtro\fzd10, Xtro\fzd3, Xtro\smo, Xtro\fzd9, Xtro\frzb, Xtro\fzd4, Xtro\fzd7, Xtro\frzb2, Xtro\fzd8, Xtro\fzd6, Xtro\szl, Xtro\xepsin, Xtro\sfrp2, Xtro\sfrpx, Xtro\sfrp5, Xtro\col18a1, Xtro\fzd5" "Mmus\Prss55, Mmus\Loxl3, Mmus\Fzd10, Mmus\Fzd4, Mmus\Cd163, Mmus\Ssc5d, Mmus\Sfrp2, Mmus\Ssc4d, Mmus\Smo, Mmus\C1ra, Mmus\C1rb, Mmus\Pik3ip1, Mmus\Fzd2, Mmus\Fzd6, Mmus\Sfrp4, Mmus\Cd163l1, Mmus\Fzd5, Mmus\Hpn, Mmus\Frzb, Mmus\Sfrp1, Mmus\Fzd7, Mmus\Dmbt1, Mmus\Sfrp5, Mmus\Pamr1, Mmus\Corin, Mmus\Fzd9, Mmus\Fzd8, Mmus\5830411N06Rik, Mmus\Fzd3, Mmus\Gm21451, Mmus\Prss54, Mmus\Fzd1, Mmus\Mfrp" "Hsap\FRZB, Hsap\PRSS54, Hsap\FZD4, Hsap\SFRP5, Hsap\FZD8, Hsap\FZD7, Hsap\CD163L1, Hsap\FZD5, Hsap\SSC5D, Hsap\PRSS55, Hsap\MFRP, Hsap\CD163, Hsap\FZD9, Hsap\FZD1, Hsap\SFRP4, Hsap\FZD6, Hsap\FZD3, Hsap\PAMR1, Hsap\SSC4D, Hsap\HPN, Hsap\FZD10, Hsap\FZD2, Hsap\SFRP2, Hsap\SFRP1, Hsap\C1R, Hsap\C1S, Hsap\MASP2, Hsap\LOXL2, Hsap\CORIN, Hsap\SMO, Hsap\PIK3IP1" viable DRSC06818 IE 1.596393932 -0.11992282 -0.121184606 2.284410419 0.285736736 -0.015319946 FBgn0020588 anon-57Ci anon-57Ci http://flybase.org/reports/FBgn0020588 - gene - - - anon-57Ci - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011310 l(3)j1B9 lethal (3) j1B9 http://flybase.org/reports/FBgn0011310 - gene - - - l(3)j1B9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022186 l(2)k05204 lethal (2) k05204 http://flybase.org/reports/FBgn0022186 - gene - - - l(2)k05204 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0250732 gfzf GST-containing FLYWCH zinc-finger protein http://flybase.org/reports/FBgn0250732 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity glutathione binding ; GO:0043295 | inferred from direct assay glutathione transferase activity ; GO:0004364 | inferred from sequence or structural similarity mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D cytoplasm ; GO:0005737 | inferred from direct assay "CG10065, l(3)84Cc, Su(Kpn), gfzf, dGFZF, CG31492, CG31329, GFZF, CG33546, cg10065" "IPR012336:Thioredoxin-like fold, IPR010987:Glutathione S-transferase, C-terminal-like, IPR007588:Zinc finger, FLYWCH-type, IPR004046:Glutathione S-transferase, C-terminal, IPR004045:Glutathione S-transferase, N-terminal" CG33546 11-Aug-17 DroID_v2017_08 "Drer\gstt2, Drer\gstr, Drer\gstt1b, Drer\gstt1a, Drer\eef1e1, Drer\eef1g, Drer\vars, Drer\mars" "Scer\URE2, Scer\CAM1, Scer\GTT1, Scer\YGR201C, Scer\GTT2, Scer\TEF4" Cele\gsto-1 "Xtro\eef1g, Xtro\gstt1, Xtro\eef1e1" "Mmus\Gstt3, Mmus\Gstt1, Mmus\Eef1g, Mmus\Gstt4, Mmus\Vars, Mmus\Mars, Mmus\Gsto2, Mmus\Eef1e1, Mmus\Gstt2" "Hsap\GSTT2, Hsap\MARS, Hsap\GSTT2B, Hsap\EEF1G, Hsap\VARS, Hsap\GSTT1, Hsap\GSTO2, Hsap\EEF1E1" DRSC12506 I -1.368200364 -2.331916139 -0.757068307 -0.032619127 0.525888467 -0.276407695 FBgn0001952 l(2)28Aa lethal (2) 28Aa http://flybase.org/reports/FBgn0001952 - gene - - - "J, l(2)28Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "wing vein,wing hair,sex comb" FBgn0041710 yellow-f yellow-f http://flybase.org/reports/FBgn0041710 protein_coding_gene dopachrome isomerase activity ; GO:0004167 | inferred from direct assay developmental pigmentation ; GO:0048066 | inferred by curator from GO:0004167 developmental pigmentation ; GO:0048066 | traceable author statement cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 indole-containing compound biosynthetic process ; GO:0042435 | inferred from direct assay melanin biosynthetic process from tyrosine ; GO:0006583 | traceable author statement melanin biosynthetic process from tyrosine ; GO:0006583 | inferred by curator from GO:0004167 extracellular region ; GO:0005576 | inferred from direct assay "CG18550, yellow-f, yell-f" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG18550 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\C24H12.1, Cele\fbxa-76, Cele\T27A1.3, Cele\F49E11.8" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 viable FBgn0264267 CR43767 - http://flybase.org/reports/FBgn0264267 non_protein_coding_gene - - - CR43767 - CR43767 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052988 CG32988 - http://flybase.org/reports/FBgn0052988 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18663, CG32988" - CG32988 11-Aug-17 DroID_v2017_08 - - Cele\ZC13.2 - - - viable FBgn0015518 ms(2)HB30 male sterile (2) HB30 http://flybase.org/reports/FBgn0015518 - gene - - - ms(2)HB30 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065846 l(2)SH0318 lethal (2) SH0318 http://flybase.org/reports/FBgn0065846 gene - - - "l(2)SH0318, l(2)SH2 0318" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044462 EP3289 EP3289 http://flybase.org/reports/FBgn0044462 gene - - - EP3289 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "germline cell,male,anterior fascicle & synapse,intersegmental nerve" FBgn0262992 CR43300 - http://flybase.org/reports/FBgn0262992 non_protein_coding_gene - - - CR43300 - CR43300 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060985 l(3)S028206b lethal (3) S028206b http://flybase.org/reports/FBgn0060985 gene - - - "0282/06, l(3)S028206b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267590 CR45928 - http://flybase.org/reports/FBgn0267590 non_protein_coding_gene - - - CR45928 - CR45928 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003366 sev sevenless http://flybase.org/reports/FBgn0003366 "FBgn0022796, FBgn0026795, FBgn0026831, FBgn0026832" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002011, InterPro:IPR017441 transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from sequence or structural similarity transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with drk protein binding ; GO:0005515 | inferred from physical interaction with Dab protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with boss" "transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from electronic annotation with InterPro:IPR002011 R7 cell differentiation ; GO:0045466 | traceable author statement R7 cell development ; GO:0045467 | non-traceable author statement positive regulation of photoreceptor cell differentiation ; GO:0046534 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement R7 cell fate commitment ; GO:0007465 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement positive regulation of R7 cell differentiation ; GO:0045678 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype R8 cell fate specification ; GO:0045464 | inferred from mutant phenotype peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from direct assay torso signaling pathway ; GO:0008293 | non-traceable author statement" plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay "Sev, CT3980, CG18085, DROSEV1, DmHD-265, sev(AC)[[14]], DROSEV, 7less, 7LES, HD-265, sev, SEV" "IPR011042:Six-bladed beta-propeller, TolB-like, IPR000719:Protein kinase domain, IPR002011:Tyrosine-protein kinase, receptor class II, conserved site, IPR003961:Fibronectin type III, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR000033:LDLR class B repeat, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR013783:Immunoglobulin-like fold" CG18085 11-Aug-17 DroID_v2017_08 "Drer\met, Drer\mst1ra, Drer\ros1, Drer\mst1rb, Drer\ltk" - Cele\rol-3 "Xtro\met, Xtro\mst1r, Xtro\ros1" "Mmus\Alk, Mmus\Ros1, Mmus\Mst1r, Mmus\Insrr, Mmus\Ltk, Mmus\Met" "Hsap\ROS1, Hsap\MET, Hsap\ALK, Hsap\INSRR, Hsap\LTK, Hsap\MST1R" " adult stage , larval stage | third instar " " imaginal disc

, adult head

" "viable,fertile,neuroanatomy defective,phototaxis defective,wild-type,visual behavior defective,heat sensitive,visible,recessive,lethal,partially,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage" "photoreceptor cell R7,eye,supernumerary,ommatidium,distal medullary amacrine neuron Dm8,rhabdomere R7,heat sensitive,photoreceptor cell R8,photoreceptor cell R8 of yellow ommatidium,ectopic,photoreceptor cell R7 of pale ommatidium,photoreceptor cell,photoreceptor cell R8 of pale ommatidium,pale ommatidium,somatic clone,rhabdomere,photoreceptor cell R6,photoreceptor cell R1,eye photoreceptor cell,denticle belt,embryonic/first instar larval cuticle,embryonic head,cone cell,embryonic/larval tracheal system" FBgn0032129 jp junctophilin http://flybase.org/reports/FBgn0032129 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available junctional membrane complex ; GO:0030314 | inferred from sequence or structural similarity with UniProtKB:Q9GKY8 "JP, CG13115, CG4405, jp" IPR003409:MORN motif CG4405 11-Aug-17 DroID_v2017_08 "Drer\morn4, Drer\rsph1, Drer\rsph10b, Drer\als2a, Drer\jph2, Drer\jph3, Drer\jph1b, Drer\als2b, Drer\si:ch211-146m13.3, Drer\jph1a" - Cele\jph-1 "Xtro\als2, Xtro\morn5, Xtro\jph2, Xtro\als2cl, Xtro\rsph10b, Xtro\rsph1, Xtro\jph1" "Mmus\Morn3, Mmus\Jph1, Mmus\Jph2, Mmus\Rsph1, Mmus\Als2, Mmus\Als2cl, Mmus\Morn1, Mmus\Jph3, Mmus\Morn5, Mmus\Jph4, Mmus\Morn4" "Hsap\MORN3, Hsap\MORN4, Hsap\ALS2CL, Hsap\MORN1, Hsap\RSPH1, Hsap\ALS2, Hsap\JPH1, Hsap\JPH3, Hsap\JPH4, Hsap\JPH2, Hsap\RSPH10B2, Hsap\RSPH10B, Hsap\MORN5" "viable,fertile,lethal" FBgn0266925 CR45376 - http://flybase.org/reports/FBgn0266925 non_protein_coding_gene - - - CR45376 - CR45376 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052153 tRNA:Met-CAT-1-3 transfer RNA:Methionine-CAT 1-3 http://flybase.org/reports/FBgn0052153 tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "AE002602.trna24-MetCAT, tRNA:M:CAT:AE002602-c, CR32153, tRNA:M2:72Fa, tRNA:met2:72Fa, tRNA:M2:72Fb, tRNA:met2:72Fb, tRNA[[2]][Met], chr3L.trna29-MetCAT, tRNA-Met[CAU], tRNA-Met-CAT-1-3, tRNA:Met-CAT-1-3, tRNA:CR32153" - CR32153 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034325 CG18539 - http://flybase.org/reports/FBgn0034325 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18539 IPR010512:Protein of unknown function DUF1091 CG18539 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0034291 CG5770 - http://flybase.org/reports/FBgn0034291 protein_coding_gene - - - "BcDNA:LP06072, CG5770" IPR007931:Protein of unknown function DUF725 CG5770 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" trichogen cell FBgn0003262 rmp rumpled http://flybase.org/reports/FBgn0003262 - gene - - - "rm, rmp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible" "wing,macrochaeta,postvertical bristle" FBgn0087039 Sbp2 SECIS-binding protein 2 http://flybase.org/reports/FBgn0087039 protein_coding_gene RNA stem-loop binding ; GO:0035613 | inferred from direct assay mRNA 3'-UTR binding ; GO:0003730 | inferred from biological aspect of ancestor with PANTHER:PTN000328589 ribonucleoprotein complex binding ; GO:0043021 | inferred from biological aspect of ancestor with PANTHER:PTN000328589 selenocysteine insertion sequence binding ; GO:0035368 | inferred from direct assay selenocysteine incorporation ; GO:0001514 | inferred from direct assay positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay "SBP2, Sbp2, CG7066" "IPR004038:Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR029064:50S ribosomal protein L30e-like" CG7066 11-Aug-17 DroID_v2017_08 "Drer\snu13a, Drer\snu13b" Scer\SNU13 Cele\scbp-2 "Xtro\snu13, Xtro\secisbp2l" "Mmus\Secisbp2, Mmus\Nhp2l1, Mmus\Secisbp2l" "Hsap\SECISBP2, Hsap\SNU13, Hsap\SECISBP2L" FBgn0278604 dmt dalmatian http://flybase.org/reports/FBgn0278604 protein_coding_gene - "primary branching, open tracheal system ; GO:0007428 | inferred from mutant phenotype cellular response to radiation ; GO:0071478 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype mitotic sister chromatid cohesion ; GO:0007064 | inferred from mutant phenotype trachea development ; GO:0060438 | inferred from mutant phenotype salivary gland development ; GO:0007431 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | NOT inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence model chromatin ; GO:0000785 | colocalizes_with inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay "aul, dmt, CG8374, s048103, 0481/03, anon-WO0118547.317, Dmt" IPR018605:Sororin protein CG8374 11-Aug-17 DroID_v2017_08 - - - - - - DRSC16932 E -0.20827368 -1.479261786 -0.70036734 -2.705504916 -0.254537113 -0.387448276 FBgn0043799 CG31381 - http://flybase.org/reports/FBgn0043799 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR018022 - "BEST:LD10347, CG31381" "IPR018022:tRNA dimethylallyltransferase, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013087:Zinc finger C2H2-type, IPR022755:Zinc finger, double-stranded RNA binding" CG31381 11-Aug-17 DroID_v2017_08 Drer\trit1 Scer\MOD5 Cele\gro-1 Xtro\trit1 Mmus\Trit1 Hsap\TRIT1 viable FBgn0259759 ms(3)Z5802 - http://flybase.org/reports/FBgn0259759 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "167-072, ms(3)Z5802, ms(3)167-72" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male sterile" Y chromosome loop FBgn0065044 wkp weak processes http://flybase.org/reports/FBgn0065044 gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available wkp - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,somatic clone" "embryonic/larval mushroom body,somatic clone" FBgn0037526 ArgRS-m "Arginyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0037526 protein_coding_gene "arginine-tRNA ligase activity ; GO:0004814 | inferred from electronic annotation with InterPro:IPR001278, InterPro:IPR008909 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001278, InterPro:IPR001412, InterPro:IPR008909, InterPro:IPR009080 arginine-tRNA ligase activity ; GO:0004814 | traceable author statement" "arginyl-tRNA aminoacylation ; GO:0006420 | inferred from electronic annotation with InterPro:IPR001278, InterPro:IPR008909 mitochondrial translation ; GO:0032543 | inferred from biological aspect of ancestor with PANTHER:PTN000238101 arginyl-tRNA aminoacylation ; GO:0006420 | traceable author statement" mitochondrion ; GO:0005739 | traceable author statement mitochondrion ; GO:0005739 | inferred from direct assay "atl, ArgRS-m, CG10092" "IPR001278:Arginine-tRNA ligase, IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR008909:DALR anticodon binding, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG10092 11-Aug-17 DroID_v2017_08 "Drer\rars, Drer\rars2, Drer\dalrd3" "Scer\MSR1, Scer\YDR341C" "Cele\rars-2, Cele\rars-1" "Xtro\rars, Xtro\rars2" "Mmus\Dalrd3, Mmus\Rars, Mmus\Rars2" "Hsap\RARS2, Hsap\RARS, Hsap\DALRD3" "visible,recessive,somatic clone" "eye,somatic clone,eye disc" DRSC14186 IK 2.61426818 -0.490853208 0.056437149 0.339983349 2.935498272 -0.209491786 FBgn0083947 CG34111 - http://flybase.org/reports/FBgn0083947 protein_coding_gene - - - "CG13825, CG34111" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060859 l(3)S047909 lethal (3) S047909 http://flybase.org/reports/FBgn0060859 gene - - - "0479/09, l(3)S047909" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262413 mir-9b mir-9b stem loop http://flybase.org/reports/FBgn0262413 miRNA_gene - imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype - "mir-9b, miR-9b, 9b, dme-mir-9b, MIR-9, CR42960, CR33563, miR-9, mir-9B, mir-9, pri-miR-9b, miRNA-9b, miR9b, dme-miR-9b" - CR42960 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage "visible,lethal" "eye,wing,wing margin,wing margin bristle,triple row" FBgn0039490 CG5882 - http://flybase.org/reports/FBgn0039490 protein_coding_gene - - - CG5882 - CG5882 11-Aug-17 DroID_v2017_08 "Drer\cfap58, Drer\ccdc146" - Cele\C23H4.6 "Xtro\cfap58, Xtro\ccdc146" "Mmus\Ccdc146, Mmus\Cfap58, Mmus\Ccdc110" "Hsap\CFAP58, Hsap\CCDC110, Hsap\CCDC146" "viable,visible" "chaeta,supernumerary" FBgn0039491 CG6059 - http://flybase.org/reports/FBgn0039491 protein_coding_gene - - - CG6059 - CG6059 11-Aug-17 DroID_v2017_08 "Drer\ccdc146, Drer\traip, Drer\cfap58" - Cele\C23H4.6 "Xtro\ccdc146, Xtro\cfap58" "Mmus\Ccdc110, Mmus\Cfap58, Mmus\Ccdc146" "Hsap\CFAP58, Hsap\CCDC146, Hsap\CCDC110" viable FBgn0014184 Oda Ornithine decarboxylase antizyme http://flybase.org/reports/FBgn0014184 "FBgn0010521, FBgn0014270" protein_coding_gene ornithine decarboxylase inhibitor activity ; GO:0008073 | inferred from biological aspect of ancestor with PANTHER:PTN001616256 ornithine decarboxylase inhibitor activity ; GO:0008073 | inferred from sequence or structural similarity with HGNC:8095 positive regulation of protein catabolic process ; GO:0045732 | inferred from biological aspect of ancestor with PANTHER:PTN001616256 polyamine metabolic process ; GO:0006595 | inferred from biological aspect of ancestor with PANTHER:PTN001616256 nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "Oda, D-AZ, ODA, guf, AZ, CG16747, l(2)k09037, l(2)02833, oda" "IPR002993:Ornithine decarboxylase antizyme, IPR016181:Acyl-CoA N-acyltransferase" CG16747 11-Aug-17 DroID_v2017_08 "Drer\oaz2b, Drer\oaz1a, Drer\oaz2a, Drer\oaz1b" - Cele\oaz-1 "Xtro\oaz1, Xtro\oaz2" "Mmus\Oaz2, Mmus\Oaz1, Mmus\Oaz3" "Hsap\OAZ1, Hsap\OAZ2, Hsap\OAZ3" " embryonic stage | early , embryonic stage | stage >=14 , embryonic stage | stage 7-11 , embryonic stage | stage >=11 , embryonic stage -- adult stage , embryonic stage , embryonic stage | stage 12 " "

ubiquitous , embryonic/larval somatic muscle

, mesoderm

, embryonic/larval midgut

, fat body primordium

, embryonic/larval foregut

, Malpighian tubule primordium

, posterior midgut proper primordium

, embryonic peripheral nervous system

" "viable,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval salivary gland,class IV dendritic arborizing neuron,somatic clone,embryonic/larval brain,embryonic/larval lymph gland,imaginal disc,salivary gland imaginal ring,wing disc,haltere disc,ventral thoracic disc" FBgn0050198 tRNA:Ala-CGC-1-1 transfer RNA:Alanine-CGC 1-1 http://flybase.org/reports/FBgn0050198 tRNA_gene GCG codon-amino acid adaptor activity ; GO:0033456 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033456 cytosol ; GO:0005829 | inferred by curator from GO:0033456 "CR30198, AE002575.trna6-AlaCGC, tRNA:A:CGC:AE002575-a, tRNA[[Ala]], chr2R.trna50-AlaCGC, tRNA-Ala-CGC-1-1, tRNA:Ala-CGC-1-1, tRNA:CR30198, GCG" - CR30198 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035675 CG6610 - http://flybase.org/reports/FBgn0035675 protein_coding_gene RNA binding ; GO:0003723 | contributes_to inferred from sequence or structural similarity with SGD:S000000948 RNA binding ; GO:0003723 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000469347 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000948 nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from biological aspect of ancestor with PANTHER:PTN000469347 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000469347" spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000000948 U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000469347 Lsm1-7-Pat1 complex ; GO:1990726 | inferred from biological aspect of ancestor with PANTHER:PTN000469347 U6 snRNP ; GO:0005688 | inferred from biological aspect of ancestor with PANTHER:PTN000469347 "BcDNA:RE60135, CG6610" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR033871:Sm-like protein LSm5" CG6610 11-Aug-17 DroID_v2017_08 Drer\lsm5 Scer\LSM5 Cele\lsm-5 Xtro\lsm5 Mmus\Lsm5 Hsap\LSM5 FBgn0085659 CG41498 - http://flybase.org/reports/FBgn0085659 protein_coding_gene - - - CG41498 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030723 dpr18 defective proboscis extension response 18 http://flybase.org/reports/FBgn0030723 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Dpr-18, CT34788, CG14948, dpr18, Dpr18" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013151:Immunoglobulin" CG14948 11-Aug-17 DroID_v2017_08 Drer\si:ch211-264f5.6 - Cele\zig-8 "Xtro\nfasc, Xtro\obsl1" Mmus\Amica1 - "viable,visible" mesothoracic tergum FBgn0058382 CG40382 - http://flybase.org/reports/FBgn0058382 protein_coding_gene - - - CG40382 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051268 CG31268 - http://flybase.org/reports/FBgn0051268 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31268 IPR008160:Collagen triple helix repeat CG31268 11-Aug-17 DroID_v2017_08 Drer\si:dkey-21p1.3 - "Cele\dpy-7, Cele\col-109, Cele\Y53C10A.10, Cele\col-104, Cele\col-106" - - - "viable,fertile" FBgn0264553 CR43932 - http://flybase.org/reports/FBgn0264553 non_protein_coding_gene - - - CR43932 - CR43932 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065906 l(2)SH0191 lethal (2) SH0191 http://flybase.org/reports/FBgn0065906 gene - - - "l(2)SH0191, l(2)SH2 0191" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030883 CG7772 - http://flybase.org/reports/FBgn0030883 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrial fission ; GO:0000266 | inferred from sequence or structural similarity with HGNC:26945 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with HGNC:26945 "bs13c01.y1, CG7772" IPR019560:Mitochondrial 18kDa protein CG7772 11-Aug-17 DroID_v2017_08 Drer\mtfp1 - Cele\mtp-18 Xtro\mtfp1 Mmus\Mtfp1 Hsap\MTFP1 "viable,fertile" FBgn0265991 Zasp52 Z band alternatively spliced PDZ-motif protein 52 http://flybase.org/reports/FBgn0265991 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 muscle alpha-actinin binding ; GO:0051371 | inferred from mutant phenotype actinin binding ; GO:0042805 | inferred from physical interaction with Actn muscle alpha-actinin binding ; GO:0051371 | inferred from physical interaction with Actn actin binding ; GO:0003779 | inferred from physical interaction with UniProtKB:P18091 protein binding ; GO:0005515 | inferred from physical interaction with egg regulation of cell-matrix adhesion ; GO:0001952 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype muscle structure development ; GO:0061061 | inferred from mutant phenotype Z disc ; GO:0030018 | inferred from direct assay cell leading edge ; GO:0031252 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay stress fiber ; GO:0001725 | inferred from direct assay zonula adherens ; GO:0005915 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay actin cytoskeleton ; GO:0015629 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay muscle tendon junction ; GO:0005927 | inferred from direct assay "Zasp52, CG30084, Zasp, Z(210), zasp, zasp52, CG8242, CG12969, tungus, tun, CG12968, dzasp, ZASP52, Zbp210" "IPR001478:PDZ domain, IPR001781:Zinc finger, LIM-type, IPR006643:Zasp-like motif, IPR015943:WD40/YVTN repeat-like-containing domain, IPR018247:EF-Hand 1, calcium-binding site, IPR031847:Domain of unknown function DUF4749" CG30084 11-Aug-17 DroID_v2017_08 "Drer\dmbx1a, Drer\shox2, Drer\lhx6, Drer\pdlim7, Drer\pdlim2, Drer\ldb3a, Drer\pax6b, Drer\ldb3b, Drer\pdlim5b, Drer\pxna, Drer\pdlim1, Drer\pdlim3b, Drer\pdlim4, Drer\gsc, Drer\pitx1, Drer\mxtx2, Drer\si:rp71-15d4.1, Drer\pitx3, Drer\hoxb8a, Drer\pdlim3a, Drer\shox, Drer\pax6a, Drer\pxnb, Drer\pdlim5a, Drer\dmbx1b, Drer\LOC103910026" "Scer\PXL1, Scer\YHP1, Scer\PHO2, Scer\LRG1" "Cele\vab-3, Cele\ZK1321.4, Cele\lim-4, Cele\alp-1, Cele\pxl-1, Cele\ceh-45, Cele\ceh-51" "Xtro\pdlim4, Xtro\pxn, Xtro\pdlim1, Xtro\hoxb8, Xtro\pdlim7, Xtro\pdlim3, Xtro\pitx1, Xtro\lhx8, Xtro\pdlim5, Xtro\pitx3, Xtro\tgfb1i1, Xtro\gsc, Xtro\shox2" "Mmus\Lhx6, Mmus\Gsc, Mmus\Lhx8, Mmus\Lpxn, Mmus\Dmbx1, Mmus\Pdlim1, Mmus\Pitx3, Mmus\Pdlim3, Mmus\Pitx1, Mmus\Pdlim4, Mmus\Pxn, Mmus\Shox2, Mmus\Tgfb1i1, Mmus\Pdlim2, Mmus\Pdlim5, Mmus\Pdlim7, Mmus\Gsc2, Mmus\Pax6, Mmus\Ldb3" "Hsap\PDLIM7, Hsap\DMBX1, Hsap\SHOX, Hsap\HOXB8, Hsap\ZYX, Hsap\GSC2, Hsap\PDLIM1, Hsap\LHX6, Hsap\PAX6, Hsap\TGFB1I1, Hsap\LHX8, Hsap\GSC, Hsap\TRIP6, Hsap\PDLIM5, Hsap\SHOX2, Hsap\WTIP, Hsap\LDB3, Hsap\PDLIM3, Hsap\LPXN, Hsap\AJUBA, Hsap\LPP, Hsap\PITX3, Hsap\PITX1, Hsap\PXN, Hsap\PDLIM2, Hsap\PDLIM4" DRSC06269 I -2.114324652 -3.937319585 -1.254712741 -0.048463324 1.252106299 1.1167684 FBgn0033853 CG6145 - http://flybase.org/reports/FBgn0033853 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from sequence or structural similarity with SGD:S000003810 NAD metabolic process ; GO:0019674 | inferred from electronic annotation with InterPro:IPR017437 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype NADP biosynthetic process ; GO:0006741 | inferred from sequence or structural similarity with SGD:S000003810 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000003810 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003810 "CT19307, CG6145" "IPR002504:NAD kinase, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR017437:ATP-NAD kinase, PpnK-type, all-beta, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG6145 11-Aug-17 DroID_v2017_08 "Drer\nadka, Drer\nadkb" "Scer\UTR1, Scer\POS5, Scer\YEF1" Cele\Y77E11A.2 Xtro\nadk Mmus\Nadk Hsap\NADK viable FBgn0069945 CG41090 - http://flybase.org/reports/FBgn0069945 protein_coding_gene - - - CG41090 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065857 l(2)SH0288 lethal (2) SH0288 http://flybase.org/reports/FBgn0065857 gene - - - "l(2)SH0288, l(2)SH2 0288" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028149 l(3)S044823 lethal (3) S044823 http://flybase.org/reports/FBgn0028149 gene - - - "0448/23, l(3)S044823" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0023512 eIF2Bepsilon eukaryotic translation initiation factor 2B subunit epsilon http://flybase.org/reports/FBgn0023512 FBgn0063784 protein_coding_gene nucleotidyltransferase activity ; GO:0016779 | inferred from electronic annotation with InterPro:IPR005835 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000002619 guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from direct assay translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translational initiation ; GO:0006413 | inferred from sequence or structural similarity translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD:S000002619 cytosol ; GO:0005829 | inferred from sequence or structural similarity eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity eukaryotic translation initiation factor 2B complex ; GO:0005851 | traceable author statement "elf2B-epsilon, EG:86E4.1, CG3806, eIF2Bepsilon, eIF2B-epsilon, eIF-2bepsilon" "IPR003307:W2 domain, IPR016024:Armadillo-type fold, IPR001451:Hexapeptide repeat, IPR029044:Nucleotide-diphospho-sugar transferases, IPR005835:Nucleotidyl transferase domain" CG3806 11-Aug-17 DroID_v2017_08 Drer\eif2b5 Scer\GCD6 Cele\D2085.3 Xtro\eif2b5 Mmus\Eif2b5 Hsap\EIF2B5 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0031109 Obp19a Odorant-binding protein 19a http://flybase.org/reports/FBgn0031109 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from biological aspect of ancestor with PANTHER:PTN000482914 dibutyl phthalate binding ; GO:0035275 | inferred from biological aspect of ancestor with PANTHER:PTN000482914 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 diphenyl phthalate binding ; GO:0035274 | inferred from biological aspect of ancestor with PANTHER:PTN000482914 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 olfactory behavior ; GO:0042048 | inferred from biological aspect of ancestor with PANTHER:PTN000482914 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 response to pheromone ; GO:0019236 | inferred from sequence or structural similarity with UniProtKB:O02372 olfactory behavior ; GO:0042048 | inferred from sequence or structural similarity with UniProtKB:O02372 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000482914 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:O02372 extracellular region ; GO:0005576 | inferred from sequence model extracellular region ; GO:0005576 | inferred from biological aspect of ancestor with PANTHER:PTN000482914 "19a, CG11748, OBP19a, Obp19a, DmelObp19a" IPR006170:Pheromone/general odorant binding protein CG11748 11-Aug-17 DroID_v2017_08 - - Cele\C35A11.2 - - - viable FBgn0028476 Usp1 Ubiquitin specific protease 1 http://flybase.org/reports/FBgn0028476 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from electronic annotation with InterPro:IPR033815 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:12607 regulation of DNA repair ; GO:0006282 | inferred from electronic annotation with InterPro:IPR033815 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:12607 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:12607 "LD22910, BcDNA:LD22910, CG15817, Usp1, Q8I077, usp1" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR033815:Ubiquitin specific peptidase 1, IPR028889:Ubiquitin specific protease domain" CG15817 11-Aug-17 DroID_v2017_08 "Drer\usp46, Drer\usp38, Drer\usp1, Drer\usp12a, Drer\usp12b" "Scer\UBP13, Scer\UBP9" Cele\usp-46 "Xtro\usp1, Xtro\hapln3, Xtro\usp46, Xtro\usp35" "Mmus\Usp38, Mmus\Usp46, Mmus\Usp1, Mmus\Usp35, Mmus\Usp12" "Hsap\USP46, Hsap\USP12, Hsap\USP35, Hsap\USP38, Hsap\USP1" "viable,fertile,locomotor behavior defective" FBgn0024185 trg trithoraxgleich http://flybase.org/reports/FBgn0024185 - gene - germ cell migration ; GO:0008354 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement - trg - - 11-Aug-17 DroID_v2017_08 - - - - - - "gonad,precursor" FBgn0265762 CG44569 - http://flybase.org/reports/FBgn0265762 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44569 - CG44569 11-Aug-17 DroID_v2017_08 Drer\enosf1 - - Xtro\enosf1 - - FBgn0065306 l(2)SH1968 lethal (2) SH1968 http://flybase.org/reports/FBgn0065306 gene - - - "l(2)SH1968, l(2)SH2 1968" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024239 feng feng http://flybase.org/reports/FBgn0024239 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available feng - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263330 CR43411 - http://flybase.org/reports/FBgn0263330 non_protein_coding_gene - - - CR43411 - CR43411 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067739 l(1)G0314 lethal (1) G0314 http://flybase.org/reports/FBgn0067739 gene - - - l(1)G0314 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0061177 bcd::Ubx bcd::Ubx http://flybase.org/reports/FBgn0061177 engineered_fusion_gene - - - bcd::Ubx - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266669 Sec3 Secretory 3 http://flybase.org/reports/FBgn0266669 protein_coding_gene "phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from biological aspect of ancestor with PANTHER:PTN000412973 phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from sequence or structural similarity with SGD:S000000810 GTP-Rho binding ; GO:0017049 | inferred from biological aspect of ancestor with PANTHER:PTN000412973" exocyst localization ; GO:0051601 | inferred from biological aspect of ancestor with PANTHER:PTN000412973 exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000412973 Golgi to plasma membrane transport ; GO:0006893 | inferred from biological aspect of ancestor with PANTHER:PTN000412973 exocyst ; GO:0000145 | inferred from biological aspect of ancestor with PANTHER:PTN000412973 exocyst ; GO:0000145 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000412973 "sec3, CG3885, Sec3" "IPR028258:Exocyst complex component Sec3, PIP2-binding N-terminal domain, IPR019160:Exocyst complex component Sec3, C-terminal, IPR011993:PH domain-like" CG3885 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-245p14.4, Drer\stxbp6l, Drer\exoc1" Scer\SEC3 Cele\sec-3 "Xtro\stxbp6, Xtro\exoc1" "Mmus\Stxbp6, Mmus\Exoc1" "Hsap\EXOC1, Hsap\STXBP6" FBgn0060720 l(3)SzB63Cb lethal (3) SzB63Cb http://flybase.org/reports/FBgn0060720 gene - - - "0686/09, l(3)S068609a, l(3)SzB63Cb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0083969 CG34133 - http://flybase.org/reports/FBgn0083969 protein_coding_gene - - - "CG7814, CG31035, anon-WO0118547.417, CG34133" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR020472:G-protein beta WD-40 repeat" CG34133 11-Aug-17 DroID_v2017_08 "Drer\wdr26a, Drer\wdr44" "Scer\DGR2, Scer\YMR102C, Scer\TUP1" Cele\sym-4 Xtro\wdr44 Mmus\Wdr44 Hsap\WDR44 "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0004202 l(3)84Dd lethal (3) 84Dd http://flybase.org/reports/FBgn0004202 - gene - - - l(3)84Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013707 mt:tRNA:Thr-TGT mitochondrial transfer RNA:Threonine-TGT http://flybase.org/reports/FBgn0013707 FBgn0002867 tRNA_gene - - - "CR34087, tRNA-Thr, mtdbD00006309, tRNA[Thr], mt:tRNA:Thr-TGT, mt:tRNA:T, tRNA-thr" - CR34087 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032681 CG10283 - http://flybase.org/reports/FBgn0032681 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from sequence or structural similarity with HGNC:18111 biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:18111 CG10283 "IPR029311:Coiled-coil domain-containing protein 50, N-terminal" CG10283 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-6k16.1, Drer\si:dkey-264d12.1, Drer\ccdc187" - Cele\R10H1.1 "Xtro\ccdc50, Xtro\LOC100145446" Mmus\Ccdc50 Hsap\CCDC50 FBgn0065536 l(2)SH1078 lethal (2) SH1078 http://flybase.org/reports/FBgn0065536 gene - - - "l(2)SH1078, l(2)SH2 1078" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260793 2mit 2mit http://flybase.org/reports/FBgn0260793 protein_coding_gene molecular_function ; GO:0003674 | no biological data available short-term memory ; GO:0007614 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG42573, CT38314, CG17319, CT28541, CG10148, 2mit" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype" CG42573 11-Aug-17 DroID_v2017_08 "Drer\tlr8b, Drer\si:dkey-182i3.11" Scer\CYR1 Cele\let-4 - Mmus\Tlr3 Hsap\TLR3 FBgn0001599 l(1)CP9 lethal (1) CP9 http://flybase.org/reports/FBgn0001599 - gene - - - l(1)CP9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030947 CG6696 - http://flybase.org/reports/FBgn0030947 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026" - CG6696 "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG6696 11-Aug-17 DroID_v2017_08 "Drer\bmp1b, Drer\bmp1a, Drer\LOC797085, Drer\csmd1a, Drer\si:ch73-40a17.3, Drer\c6ast3, Drer\tnfaip6, Drer\neto1, Drer\si:cabz01033205.3, Drer\mep1a.2, Drer\si:ch211-167j6.5, Drer\LOC100003133, Drer\npsn, Drer\cdcp2, Drer\c6ast4, Drer\tll1, Drer\mep1a.1, Drer\he2, Drer\mep1b, Drer\he1b, Drer\neto1l, Drer\neto2b, Drer\he1a, Drer\c6ast1" - "Cele\ZC116.3, Cele\nas-33, Cele\nas-4, Cele\nas-7, Cele\nas-6, Cele\nas-1, Cele\nas-15, Cele\nas-28, Cele\nas-2, Cele\nas-8, Cele\nas-9, Cele\nas-14, Cele\nas-13, Cele\nas-39, Cele\nas-12, Cele\Y19D10A.6" "Xtro\mep1a, Xtro\mep1b, Xtro\uvs.2, Xtro\tll1, Xtro\cubn, Xtro\tnfaip6, Xtro\bmp1, Xtro\LOC100492324, Xtro\accs, Xtro\tll2, Xtro\LOC100489456" "Mmus\Tll2, Mmus\Tnfaip6, Mmus\Mfrp, Mmus\Cubn, Mmus\Bmp1, Mmus\Adgrg6, Mmus\Tll1, Mmus\Neto2, Mmus\Neto1, Mmus\Mep1b, Mmus\Mep1a, Mmus\Astl, Mmus\Cdcp2" "Hsap\MEP1B, Hsap\CUBN, Hsap\ADGRG6, Hsap\CDCP2, Hsap\TLL1, Hsap\TNFAIP6, Hsap\BMP1, Hsap\MEP1A, Hsap\TLL2, Hsap\NETO2, Hsap\MFRP, Hsap\ASTL, Hsap\NETO1" "viable,visible" mesothoracic tergum FBgn0032132 CG4382 - http://flybase.org/reports/FBgn0032132 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4382 "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG4382 11-Aug-17 DroID_v2017_08 "Drer\nlgn3b, Drer\nlgn2b, Drer\nlgn4b, Drer\nlgn1, Drer\nlgn4a, Drer\nlgn3a, Drer\cel.1, Drer\si:ch211-93f2.1, Drer\ces3, Drer\nlgn2a, Drer\cell, Drer\ces2" - "Cele\C17H12.4, Cele\T07H6.1, Cele\ges-1, Cele\K07C11.4, Cele\F15A8.6, Cele\T22D1.11, Cele\ZC376.2, Cele\E01G6.3, Cele\ZC376.1, Cele\C23H4.2, Cele\C23H4.7, Cele\C23H4.4, Cele\B0238.1, Cele\C23H4.3, Cele\ZK994.1, Cele\T02B5.1, Cele\C01B10.4, Cele\F56C11.6, Cele\C42D4.2, Cele\R173.3, Cele\T02B5.3, Cele\T28C12.4, Cele\C01B10.10, Cele\F07C4.12, Cele\ace-1, Cele\ZC376.3, Cele\K11G9.2, Cele\ace-2, Cele\Y71H2AM.13, Cele\T28C12.5" "Xtro\nlgn2, Xtro\ces2, Xtro\cel, Xtro\nlgn4x, Xtro\LOC100494782, Xtro\ces3, Xtro\nlgn3" "Mmus\Ces2b, Mmus\Ces1g, Mmus\Ces5a, Mmus\Ces3b, Mmus\Nlgn2, Mmus\Ces2e, Mmus\Ache, Mmus\Ces1b, Mmus\Ces1e, Mmus\Ces4a, Mmus\Nlgn3, Mmus\Cel, Mmus\Ces2a, Mmus\Ces3a, Mmus\Ces2g, Mmus\Ces1d, Mmus\Nlgn1, Mmus\Ces1h, Mmus\Ces2c, Mmus\Ces2h, Mmus\Ces2f, Mmus\Ces1c, Mmus\Ces1f" "Hsap\NLGN2, Hsap\ACHE, Hsap\CES2, Hsap\CES4A, Hsap\CES3, Hsap\CEL, Hsap\CES5A, Hsap\NLGN4Y, Hsap\NLGN1, Hsap\CES1, Hsap\NLGN4X, Hsap\NLGN3" "viable,visible" "wing vein,ectopic" FBgn0000288 cff control of female fertility http://flybase.org/reports/FBgn0000288 - gene - - - "cf, cff" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016761 Z(400-600) Z-band-protein-400/600 http://flybase.org/reports/FBgn0016761 - gene - - - "Z(400/600), Zbp400/600, Z(400-600)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024319 Nach Nach http://flybase.org/reports/FBgn0024319 - protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium channel activity ; GO:0005272 | non-traceable author statement "liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | non-traceable author statement "ppk4, PPK4, CG8178, Nach" "IPR001873:Epithelial sodium channel, IPR020903:Epithelial sodium channel, conserved site" CG8178 11-Aug-17 DroID_v2017_08 "Drer\asic1a, Drer\asic1b, Drer\asic1c, Drer\asic4a, Drer\asic2, Drer\asic4b" - "Cele\unc-8, Cele\delm-2, Cele\flr-1, Cele\delm-1, Cele\del-7" "Xtro\asic4, Xtro\asic5, Xtro\scnn1d, Xtro\scnn1b, Xtro\scnn1a, Xtro\asic1, Xtro\scnn1g" "Mmus\Asic1, Mmus\Scnn1a, Mmus\Scnn1b, Mmus\Asic4, Mmus\Scnn1g, Mmus\Asic3, Mmus\Asic2, Mmus\Asic5" "Hsap\ASIC3, Hsap\ASIC2, Hsap\ASIC5, Hsap\SCNN1B, Hsap\ASIC4, Hsap\SCNN1G, Hsap\SCNN1D, Hsap\SCNN1A, Hsap\ASIC1" "viable,lethal" adult tracheal system FBgn0284254 Ranbp11 - http://flybase.org/reports/FBgn0284254 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001494 - "Ranbp11, CG33139, SP49, CG8212, impbeta11, imp-beta11, l(2)SH0971, l(2)SH2 0971" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG33139 11-Aug-17 DroID_v2017_08 Drer\ipo11 "Scer\KAP114, Scer\KAP120, Scer\NMD5, Scer\SXM1" Cele\xpo-2 Xtro\ipo11 Mmus\Ipo11 Hsap\IPO11 "lethal,recessive" FBgn0060887 l(3)S044632b lethal (3) S044632b http://flybase.org/reports/FBgn0060887 gene - - - "0446/32, l(3)S044632b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011776 l(2)25Eg lethal (2) 25Eg http://flybase.org/reports/FBgn0011776 - gene - - - "l(2)gdh-1, l(2)gdh1, Df(2L)sc19-4, l(2)25Eg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267482 CR45832 - http://flybase.org/reports/FBgn0267482 non_protein_coding_gene - - - CR45832 - CR45832 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039760 CG9682 - http://flybase.org/reports/FBgn0039760 protein_coding_gene - - - "anon-WO0140519.240, CG9682" - CG9682 11-Aug-17 DroID_v2017_08 - Scer\MSC1 "Cele\lea-1, Cele\dur-1" - - - viable FBgn0260619 2L2983 - http://flybase.org/reports/FBgn0260619 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2983 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0043887 l(3)S118502b lethal (3) S118502b http://flybase.org/reports/FBgn0043887 gene - - - "1185/02, l(3)S118502, l(3)S118502b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0061170 l(1)12Da lethal (1) 12Da http://flybase.org/reports/FBgn0061170 gene - - - l(1)12Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037687 CG8132 - http://flybase.org/reports/FBgn0037687 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from electronic annotation with InterPro:IPR003010" nitrogen compound metabolic process ; GO:0006807 | inferred from electronic annotation with InterPro:IPR003010 - CG8132 IPR003010:Carbon-nitrogen hydrolase CG8132 11-Aug-17 DroID_v2017_08 "Drer\nit2, Drer\nit1, Drer\btd" "Scer\NTA1, Scer\NIT3, Scer\NIT2" Cele\nft-1 "Xtro\btd, Xtro\vnn1, Xtro\nit1, Xtro\nit2" "Mmus\Btd, Mmus\Vnn1, Mmus\Nit1, Mmus\Vnn3, Mmus\Nit2" "Hsap\VNN2, Hsap\BTD, Hsap\NIT1, Hsap\NIT2, Hsap\VNN1" "viable,fertile" FBgn0261807 CG42753 - http://flybase.org/reports/FBgn0261807 protein_coding_gene - - - CG42753 - CG42753 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086601 snoRNA:Psi28S-3327c snoRNA:Psi28S-3327c http://flybase.org/reports/FBgn0086601 snoRNA_gene - - - "snoRNA:586, psi28S-3327c, Dm-586, snoR586, CR33753, Psi28S-3327c, snoRNA:Psi28S-3327c, pug28S-3327, chr3L:13017350..13017456" - CR33753 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263889 l(3)D67 - http://flybase.org/reports/FBgn0263889 gene - - - l(3)D67 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0011882 tRNA:Ile-AAT-1-4 transfer RNA:Isoleucine-AAT 1-4 http://flybase.org/reports/FBgn0011882 "FBgn0003788, FBgn0050244, FBgn0060199" tRNA_gene AUU codon-amino acid adaptor activity ; GO:0033433 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033433 cytosol ; GO:0005829 | inferred by curator from GO:0033433 "CR30244, ile-b, AE002787.trna37-IleAAT, tRNA:I:AAT:AE002787-c, tRNA:ile:49Fb, tRNA[Ile], chr2R.trna19-IleAAT, tRNA-Ile[AAU], tRNA-Ile-AAT-1-4, tRNA:Ile-AAT-1-4, tRNA:I:49Fb, AUU" - CR30244 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002627 M(3)99E Minute (3) 99E http://flybase.org/reports/FBgn0002627 - gene - - - "M(3)g, M[[g]], M(3)99E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "posterior dorsocentral bristle,posterior scutellar bristle,femur & macrochaeta" FBgn0039651 Cyt-c1L Cytochrome c1-like http://flybase.org/reports/FBgn0039651 protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR002326, InterPro:IPR009056 electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity ; GO:0045153 | inferred from biological aspect of ancestor with PANTHER:PTN002231577 electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity ; GO:0045153 | inferred from sequence or structural similarity with UniProtKB:P08574 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity ; GO:0045155 | inferred from biological aspect of ancestor with PANTHER:PTN002231577" "mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:P08574 mitochondrial ATP synthesis coupled proton transport ; GO:0042776 | inferred from biological aspect of ancestor with PANTHER:PTN000030137 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000030137" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:P08574 mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN002231577 "CG14508, CY1, Cyt-c1L" "IPR002326:Cytochrome c1, IPR009056:Cytochrome c-like domain, IPR021157:Cytochrome c1, transmembrane anchor, C-terminal" CG14508 11-Aug-17 DroID_v2017_08 Drer\cyc1 Scer\CYT1 Cele\cyc-1 - Mmus\Cyc1 Hsap\CYC1 FBgn0011555 thetaTry thetaTrypsin http://flybase.org/reports/FBgn0011555 - protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP139, CG12385, DmThetaTry, thetaTry, Try" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG12385 11-Aug-17 DroID_v2017_08 "Drer\LOC562139, Drer\si:ch211-165b19.8, Drer\zgc:112160, Drer\zgc:112038, Drer\zgc:123295, Drer\si:dkeyp-93a5.2, Drer\prss60.1, Drer\zgc:55888, Drer\tmprss4b, Drer\ctrl, Drer\prss60.3, Drer\zgc:92590, Drer\zgc:153968, Drer\try, Drer\zgc:163079, Drer\prss60.2" - Cele\try-1 - "Mmus\Prss3, Mmus\Try4, Mmus\Prss36, Mmus\Prss1, Mmus\Gm10334, Mmus\Prss55, Mmus\Prss34, Mmus\Gm5771, Mmus\Prss53, Mmus\Prss28, Mmus\Try10, Mmus\Prss2, Mmus\2210010C04Rik" "Hsap\PRSS53, Hsap\HABP2, Hsap\PRSS36, Hsap\PRSS1, Hsap\PRSS3" viable FBgn0001424 l(1)6Dh lethal (1) 6Dh http://flybase.org/reports/FBgn0001424 - gene - - - l(1)6Dh - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0036825 RpL26 Ribosomal protein L26 http://flybase.org/reports/FBgn0036825 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR005756, InterPro:IPR005825 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" large ribosomal subunit ; GO:0015934 | inferred from electronic annotation with InterPro:IPR005756 ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG6846, RpL26, RPL26, L26, Rp L26, lincRNA.S5499" "IPR005756:Ribosomal protein L26/L24, eukaryotic/archaeal, IPR005824:KOW, IPR005825:Ribosomal protein L24/L26, conserved site, IPR008991:Translation protein SH3-like domain, IPR014722:Ribosomal protein L2 domain 2" CG6846 11-Aug-17 DroID_v2017_08 Drer\rpl26 "Scer\RPL26A, Scer\RPL26B" Cele\rpl-26 Xtro\rpl26 Mmus\Rpl26 "Hsap\RPL26, Hsap\RPL26L1" lethal DRSC10726 IEK -0.323388734 -1.79363646 2.129367017 -4.48033862 0.524731367 1.66337956 FBgn0082612 T:SS-Drs Signal sequence of Drosomycin http://flybase.org/reports/FBgn0082612 engineered_tag - - - "T:SS-Drs, T:Drs" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264792 CR44022 - http://flybase.org/reports/FBgn0264792 non_protein_coding_gene - - - CR44022 - CR44022 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031229 CG3436 - http://flybase.org/reports/FBgn0031229 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:30857 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 RNA splicing ; GO:0008380 | inferred from biological aspect of ancestor with PANTHER:PTN001108918 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN001108918 precatalytic spliceosome ; GO:0071011 | inferred from direct assay CG3436 "IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG3436 11-Aug-17 DroID_v2017_08 Drer\snrnp40 "Scer\CMR1, Scer\CDC4, Scer\SWD3, Scer\PRP4" "Cele\F08G12.2, Cele\C18E3.5, Cele\B0280.9" Xtro\snrnp40 "Mmus\Snrnp40, Mmus\Tep1, Mmus\Wdr27, Mmus\Nwd1, Mmus\Dcaf4" "Hsap\WDR27, Hsap\WDR76, Hsap\WDR43, Hsap\NWD1, Hsap\DCAF4, Hsap\TEP1, Hsap\SNRNP40" viable DRSC00605 E 0.55168266 -0.624085032 3.05702244 -0.861831248 1.254604501 1.12681866 FBgn0001121 Go Gold tip http://flybase.org/reports/FBgn0001121 - gene - - - Go - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,cold sensitive,lethal,recessive" "trichome,cold sensitive,macrochaeta" FBgn0020541 l(2)DTS4 lethal (2) DTS4 http://flybase.org/reports/FBgn0020541 - gene - - - "DTSL4, l(2)DTS4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,dominant,heat sensitive,some die during pupal stage" FBgn0265468 CR44361 - http://flybase.org/reports/FBgn0265468 non_protein_coding_gene - - - CR44361 - CR44361 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004628 CabP23 Calcium-binding protein 23kD http://flybase.org/reports/FBgn0004628 FBgn0004121 gene calcium ion binding ; GO:0005509 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CabP23 - - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage , adult stage && oogenesis stage " " ovary

, pupal/adult digestive system

, adult head

" FBgn0015824 T-B9.3 T-B9.3 http://flybase.org/reports/FBgn0015824 - gene - - - T-B9.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085759 CR40640 - http://flybase.org/reports/FBgn0085759 rRNA_gene - - - CR40640 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085309 CG34280 - http://flybase.org/reports/FBgn0085309 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34280 IPR002350:Kazal domain CG34280 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035086 CG12851 - http://flybase.org/reports/FBgn0035086 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12851 - CG12851 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC04131 K 0.032654993 0.150901008 -0.480427001 0.077997968 2.978870617 -0.238076377 FBgn0038128 Ravus Ravus http://flybase.org/reports/FBgn0038128 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay "CG15889, Ravus" IPR004210:BESS motif CG15889 11-Aug-17 DroID_v2017_08 - - - - - - "non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0051118 RabX4 RabX4 http://flybase.org/reports/FBgn0051118 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" protein secretion ; GO:0009306 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 cellular response to insulin stimulus ; GO:0032869 | inferred from biological aspect of ancestor with PANTHER:PTN000756399 vesicle docking involved in exocytosis ; GO:0006904 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 recycling endosome ; GO:0055037 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000756399 synapse ; GO:0045202 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 insulin-responsive compartment ; GO:0032593 | inferred from biological aspect of ancestor with PANTHER:PTN000756399 "CG13638, AAF56345, DmRabX4, CG31118, RabX4, rabX4" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG31118 11-Aug-17 DroID_v2017_08 "Drer\zgc:162879, Drer\rab13, Drer\rasef, Drer\rab12, Drer\rab8a, Drer\rab10, Drer\rab40c, Drer\rab15, Drer\rab44, Drer\rab40b, Drer\rab8b, Drer\LOC100535415" Scer\SEC4 "Cele\K02E10.1, Cele\rab-33, Cele\rab-10" "Xtro\LOC100135070, Xtro\rasef, Xtro\rab8a, Xtro\rab13, Xtro\rab28, Xtro\rasef, Xtro\rab10, Xtro\rab15, Xtro\rab40b, Xtro\rab8b, Xtro\rab12, Xtro\rab44" "Mmus\Rasef, Mmus\Rab8a, Mmus\Rab28, Mmus\Rab40c, Mmus\Rab13, Mmus\Rab10, Mmus\Rab8b, Mmus\Rab33b, Mmus\Rab44, Mmus\Rab12, Mmus\Rab15, Mmus\Rab40b" "Hsap\RAB10, Hsap\RAB12, Hsap\RAB8A, Hsap\RAB15, Hsap\RAB40B, Hsap\RAB33B, Hsap\RAB13, Hsap\RAB40A, Hsap\RASEF, Hsap\RAB28, Hsap\RAB40AL, Hsap\RAB8B, Hsap\RAB40C" FBgn0016000 l(3)2h lethal (3) 2h http://flybase.org/reports/FBgn0016000 - gene - - - "l(3L)2h, l(3)2h" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038241 CG8087 - http://flybase.org/reports/FBgn0038241 protein_coding_gene - - - CG8087 - CG8087 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0031468 CG2975 - http://flybase.org/reports/FBgn0031468 protein_coding_gene "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 beta-1,3-galactosyltransferase activity ; GO:0048531 | inferred from direct assay" "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 protein glycosylation ; GO:0006486 | inferred from direct assay multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:24337 "CG2975, dC1GalT4" IPR003378:Fringe-like CG2975 11-Aug-17 DroID_v2017_08 "Drer\LOC564281, Drer\c1galt1b, Drer\si:dkey-202e17.1, Drer\c1galt1a, Drer\c1galt1c1" - "Cele\C16D9.6, Cele\E03H4.3, Cele\C02H6.1, Cele\Y38C1AB.1, Cele\F37A4.3, Cele\Y38C1AB.5, Cele\F56H6.1, Cele\C17A2.3, Cele\T09E11.6, Cele\T09E11.12, Cele\W09D10.5, Cele\C38H2.2, Cele\bus-4" "Xtro\c1galt1, Xtro\LOC100496837" "Mmus\C1galt1c1, Mmus\C1galt1" "Hsap\C1GALT1, Hsap\C1GALT1C1" viable FBgn0004670 Crown Crown http://flybase.org/reports/FBgn0004670 - gene - - - "Crn, Crown" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant,body color defective" FBgn0083026 snoRNA:Psi18S-640a snoRNA:Psi18S-640a http://flybase.org/reports/FBgn0083026 snoRNA_gene - - - "snoRNA:Psi18S-640a, psi18s-640a, Psi 18S-640a, CR34571" - CR34571 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266348 CR44997 - http://flybase.org/reports/FBgn0266348 non_protein_coding_gene - - - CR44997 - CR44997 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259313 EP-1008 - http://flybase.org/reports/FBgn0259313 gene - - - EP-1008 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0039737 CG7920 - http://flybase.org/reports/FBgn0039737 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR003702 acetyl-CoA metabolic process ; GO:0006084 | inferred from electronic annotation with InterPro:IPR003702 neurogenesis ; GO:0022008 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CG7920, i130, GH02390.5prime, anon-WO0153538.37, anon-WO0153538.36, BEST:GH02390" "IPR003702:Acetyl-CoA hydrolase/transferase, IPR026888:Acetyl-CoA hydrolase/transferase C-terminal domain" CG7920 11-Aug-17 DroID_v2017_08 - Scer\ACH1 "Cele\ZK1320.9, Cele\acer-1" - - - "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0002702 fme focal melanosis http://flybase.org/reports/FBgn0002702 - gene - - - "fme, me" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible" "femur,tibia" FBgn0039656 CG11951 - http://flybase.org/reports/FBgn0039656 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 CG11951 "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG11951 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-149p5.1, Drer\si:ch211-198g19.1, Drer\si:ch211-106j24.1, Drer\erap1a, Drer\si:ch211-276a23.5, Drer\lnpep, Drer\anpepb, Drer\anpepa, Drer\enpep, Drer\npepps, Drer\erap1b, Drer\erap2" "Scer\APE2, Scer\TMA108, Scer\AAP1" "Cele\T12E12.6, Cele\mnp-1, Cele\VB0395L.1, Cele\AC3.5, Cele\Y42A5A.1, Cele\Y67D8C.9, Cele\F49B2.6, Cele\R03G8.4, Cele\pam-1, Cele\T16G12.1, Cele\T07F10.1, Cele\R03G8.6, Cele\Y53F4B.20" "Xtro\enpep, Xtro\lnpep, Xtro\erap1, Xtro\lvrn, Xtro\npepps, Xtro\anpep" "Mmus\Lnpep, Mmus\Lvrn, Mmus\Enpep, Mmus\Npepps, Mmus\Trhde, Mmus\Anpep, Mmus\Erap1" "Hsap\ANPEP, Hsap\LVRN, Hsap\NPEPPS, Hsap\ENPEP, Hsap\ERAP1, Hsap\LNPEP, Hsap\ERAP2, Hsap\TRHDE" "viable,fertile" FBgn0264818 CR44026 - http://flybase.org/reports/FBgn0264818 non_protein_coding_gene - - - CR44026 - CR44026 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065100 snmRNA:254 small non-messenger RNA 254 http://flybase.org/reports/FBgn0065100 non_protein_coding_gene - - - "Dm-254, CR33705, snmRNA:254, chr2L:21668100..21668302" - CR33705 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053923 CG33923 - http://flybase.org/reports/FBgn0053923 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33923 IPR010512:Protein of unknown function DUF1091 CG33923 11-Aug-17 DroID_v2017_08 - - Cele\K12H4.7 - - - FBgn0039924 PIP4K Phosphatidylinositol 5-phosphate 4-kinase http://flybase.org/reports/FBgn0039924 protein_coding_gene 1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308 | non-traceable author statement 1-phosphatidylinositol-5-phosphate 4-kinase activity ; GO:0016309 | inferred from direct assay 1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308 | inferred from sequence or structural similarity with SGD:S000002616 regulation of TOR signaling ; GO:0032006 | inferred from genetic interaction with Rheb positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype phosphatidylinositol phosphorylation ; GO:0046854 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype phosphorylation ; GO:0016310 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "PIP5K 102E, CG17471, dPIP4K, PIP4K" "IPR002498:Phosphatidylinositol-4-phosphate 5-kinase, core, IPR023610:Phosphatidylinositol-4-phosphate 5-kinase, IPR027484:Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain, IPR027483:Phosphatidylinositol-4-phosphate 5-kinase, C-terminal" CG17471 11-Aug-17 DroID_v2017_08 "Drer\pip4k2ab, Drer\pip4k2ca, Drer\pip5k1ab, Drer\pip4k2aa, Drer\pip5kl1, Drer\pip5k1ba, Drer\pip5k1bb, Drer\pip4k2cb, Drer\pip5k1aa" Scer\MSS4 "Cele\ppk-2, Cele\ppk-1" "Xtro\pip4k2a, Xtro\pip5k1b, Xtro\pip5k1a, Xtro\pip4k2c, Xtro\pip5k1c, Xtro\pip5kl1" "Mmus\Pip5k1b, Mmus\Pip4k2a, Mmus\Pip5k1c, Mmus\Pip4k2c, Mmus\Pip5k1a, Mmus\Pip5kl1, Mmus\Pip4k2b" "Hsap\PIP4K2A, Hsap\PIP5K1B, Hsap\PIP5K1A, Hsap\PIP4K2B, Hsap\PIP4K2C, Hsap\PIP5KL1, Hsap\PIP5K1C" "small body,developmental rate defective,decreased cell size,large body,increased cell size" "embryonic/larval salivary gland,embryonic/larval salivary gland | larval stage" FBgn0001917 l(2)25Bd lethal (2) 25Bd http://flybase.org/reports/FBgn0001917 - gene - - - "jf13, l(2)jf13, l(2)25Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0264668 truncated truncated http://flybase.org/reports/FBgn0264668 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - truncated - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0040827 CG13315 - http://flybase.org/reports/FBgn0040827 protein_coding_gene - - - "CG13315, BcDNA:RH39779" - CG13315 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0038850 CG17279 - http://flybase.org/reports/FBgn0038850 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG17279 IPR010562:Haemolymph juvenile hormone binding CG17279 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002772 Mlc1 Myosin alkali light chain 1 http://flybase.org/reports/FBgn0002772 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 microfilament motor activity ; GO:0000146 | non-traceable author statement mesoderm development ; GO:0007498 | inferred from expression pattern muscle contraction ; GO:0006936 | non-traceable author statement muscle myosin complex ; GO:0005859 | inferred from direct assay myosin complex ; GO:0016459 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay "FBgn0002772, mlc, mlc1, DmMLC1, ELC, CG5596, MlcI, Mlci, mlcl, Mlc-1, mlc-alk, LC1, MLC1, MLC-ALK, Mlc1, chr3R:23484557..23484663, MLC, ELC2, ELC_3" "IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG5596 11-Aug-17 DroID_v2017_08 "Drer\zgc:153867, Drer\cmlc1, Drer\myl4, Drer\mylz3, Drer\myl6, Drer\myl1, Drer\myl13, Drer\zgc:163073" Scer\MLC1 "Cele\mlc-3, Cele\mlc-6" "Xtro\myl3, Xtro\myl6, Xtro\myl1, Xtro\myl4" "Mmus\Myl4, Mmus\Myl6b, Mmus\Myl1, Mmus\Myl3, Mmus\Myl6" "Hsap\MYL6, Hsap\MYL4, Hsap\MYL6B, Hsap\MYL1, Hsap\MYL3" " adult stage ,, pupal stage | late , larval stage && adult stage , embryonic stage | late , larval stage " " tubular muscle

, indirect flight muscle

" " larval stage , adult stage " " tubular muscle

, adult abdomen

, adult head

, leg

, indirect flight muscle

" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0069245 cst croissant http://flybase.org/reports/FBgn0069245 gene molecular_function ; GO:0003674 | no biological data available "maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available cst - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect" FBgn0032734 CG15169 - http://flybase.org/reports/FBgn0032734 protein_coding_gene - - - CG15169 - CG15169 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0065739 l(2)SH0529 lethal (2) SH0529 http://flybase.org/reports/FBgn0065739 gene - - - "l(2)SH0529, l(2)SH2 0529" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005032 e(N[8]) enhancer of Notch-8 http://flybase.org/reports/FBgn0005032 - gene - - - e(N[8]) - - 11-Aug-17 DroID_v2017_08 - - - - - - wing FBgn0043796 CG12219 - http://flybase.org/reports/FBgn0043796 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "BEST:LD26135, CG12219" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG12219 11-Aug-17 DroID_v2017_08 - Scer\MOT3 "Cele\B0310.2, Cele\che-1" - Mmus\Zfp746 - viable DRSC24690 K -0.220727953 0.896963033 -0.405255396 0.762622391 -1.649840128 -0.004041397 FBgn0265645 CR44452 - http://flybase.org/reports/FBgn0265645 non_protein_coding_gene - - - "lincRNA.279, CR44452" - CR44452 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000133 Ars-region11 Autonomous replicating sequence region 11 http://flybase.org/reports/FBgn0000133 - region - - - "DmARS-6, Ars-region11, Ars11" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259540 B2008 - http://flybase.org/reports/FBgn0259540 gene - - - B2008 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,tarsal segment,arista,unguis" FBgn0264554 CR43933 - http://flybase.org/reports/FBgn0264554 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43933, CR43933" - CR43933 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260364 GSd500 - http://flybase.org/reports/FBgn0260364 gene - - - GSd500 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020839 l(2)CP241 "Canonsburg, PA 241" http://flybase.org/reports/FBgn0020839 - gene - - - l(2)CP241 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029765 CG16756 - http://flybase.org/reports/FBgn0029765 protein_coding_gene - - - "CG16756, BcDNA:RH17440" "IPR001916:Glycoside hydrolase, family 22, IPR023346:Lysozyme-like domain, IPR019799:Glycoside hydrolase, family 22, conserved site" CG16756 11-Aug-17 DroID_v2017_08 "Drer\LOC100536671, Drer\lyz, Drer\LOC100334363" - - Xtro\MGC89221 "Mmus\Spaca3, Mmus\9530003J23Rik, Mmus\Spaca1, Mmus\Spaca5, Mmus\Lyzl4, Mmus\Lyz2, Mmus\Spaca4, Mmus\Lyz1, Mmus\1700016D06Rik, Mmus\Lalba, Mmus\Lyzl6, Mmus\Lyzl1, Mmus\Spaca7" "Hsap\LYZL2, Hsap\SPACA5, Hsap\SPACA3, Hsap\SPACA5B, Hsap\LALBA, Hsap\LYZL1, Hsap\LYZL6, Hsap\SPACA7, Hsap\LYZ, Hsap\LYZL4, Hsap\SPACA1, Hsap\SPACA4" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0260380 GSd406 - http://flybase.org/reports/FBgn0260380 gene - - - GSd406 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,intersegmental nerve" FBgn0020560 anon-VIII-E7 anon-VIII-E7 http://flybase.org/reports/FBgn0020560 - gene - - - anon-VIII-E7 - - 11-Aug-17 DroID_v2017_08 - - - - - - Bolwig nerve FBgn0000648 fd furled http://flybase.org/reports/FBgn0000648 - gene - - - fd - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "proboscis,mouthpart" FBgn0035924 CG6576 - http://flybase.org/reports/FBgn0035924 protein_coding_gene - "negative regulation of translation ; GO:0017148 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | inferred from biological aspect of ancestor with PANTHER:PTN000595684" cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 CG6576 - CG6576 11-Aug-17 DroID_v2017_08 Drer\cnot2 Scer\CDC36 "Cele\ntl-2, Cele\tag-153" - Mmus\Cnot2 Hsap\CNOT2 viable FBgn0032436 CG5418 - http://flybase.org/reports/FBgn0032436 protein_coding_gene purine nucleosidase activity ; GO:0008477 | inferred from biological aspect of ancestor with PANTHER:PTN000266727 purine nucleoside catabolic process ; GO:0006152 | inferred from biological aspect of ancestor with PANTHER:PTN000266727 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000266727 CG5418 "IPR001910:Inosine/uridine-preferring nucleoside hydrolase domain, IPR023186:Inosine/uridine-preferring nucleoside hydrolase" CG5418 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-201h21.5, Drer\si:dkey-4e7.3" Scer\URH1 "Cele\F13H8.3, Cele\Y43F8C.13" "Xtro\LOC100145000, Xtro\LOC548390, Xtro\LOC734042" - - viable FBgn0037023 CG3698 - http://flybase.org/reports/FBgn0037023 protein_coding_gene - - - CG3698 - CG3698 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060780 l(3)S060706 lethal (3) S060706 http://flybase.org/reports/FBgn0060780 gene - - - "0607/06, l(3)S060706" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0020363 anon-1A1 anon-1A1 http://flybase.org/reports/FBgn0020363 - gene - - - "1A1, anon-1A1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032882 Ns4 Nucleostemin 4 http://flybase.org/reports/FBgn0032882 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006073, InterPro:IPR030378" - - "38E.14, ns4, CG9320, dmNS4, NS4, Ns4" "IPR006073:GTP binding domain, IPR030378:Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9320 11-Aug-17 DroID_v2017_08 "Drer\lsg1, Drer\gnl1" Scer\LSG1 - "Xtro\gnl1, Xtro\lsg1" "Mmus\Gnl1, Mmus\Lsg1" "Hsap\GNL1, Hsap\LSG1" "viable,fertile" FBgn0032052 PIG-U Phosphatidylinositol glycan anchor biosynthesis class U http://flybase.org/reports/FBgn0032052 protein_coding_gene - attachment of GPI anchor to protein ; GO:0016255 | inferred from electronic annotation with InterPro:IPR009600 regulation of Golgi to plasma membrane protein transport ; GO:0042996 | inferred from mutant phenotype GPI-anchor transamidase complex ; GO:0042765 | inferred from electronic annotation with InterPro:IPR009600 "CG13089, PIG-U" IPR009600:GPI transamidase subunit PIG-U CG13089 11-Aug-17 DroID_v2017_08 Drer\pigu Scer\GAB1 "Cele\srb-7, Cele\srz-13, Cele\T22C1.3, Cele\srb-15" Xtro\pigu Mmus\Pigu Hsap\PIGU "viable,visible" "rhabdomere,somatic clone,trichogen cell" FBgn0038304 CG12241 - http://flybase.org/reports/FBgn0038304 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:25228 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:25228 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG12241 "IPR000195:Rab-GTPase-TBC domain, IPR001452:SH3 domain, IPR004012:RUN domain" CG12241 11-Aug-17 DroID_v2017_08 "Drer\tbc1d9, Drer\tbc1d10ab, Drer\sgsm3, Drer\grtp1a, Drer\si:dkey-110k5.6" "Scer\MDR1, Scer\MSB3, Scer\MSB4" "Cele\tbc-10, Cele\tbc-9, Cele\tbc-18, Cele\tbc-7, Cele\tbc-6" "Xtro\sgsm3, Xtro\tbc1d10a, Xtro\grtp1" "Mmus\Tbc1d8b, Mmus\Tbc1d10a, Mmus\Sgsm3, Mmus\Grtp1, Mmus\Tbc1d9, Mmus\Tbc1d9b, Mmus\Tbc1d8, Mmus\Tbc1d10b" "Hsap\TBC1D8B, Hsap\SGSM3, Hsap\TBC1D10A, Hsap\TBC1D8, Hsap\TBC1D10B, Hsap\TBC1D9, Hsap\TBC1D9B, Hsap\GRTP1" DRSC14481 E 1.164780678 0.64435379 1.800264879 -0.144473291 -0.696742662 -0.266888965 FBgn0267458 CR45808 - http://flybase.org/reports/FBgn0267458 non_protein_coding_gene - - - CR45808 - CR45808 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037204 CG11131 - http://flybase.org/reports/FBgn0037204 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model CG11131 "IPR004011:GYR motif, IPR004019:YLP motif" CG11131 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014944 anon-99A anon-99A http://flybase.org/reports/FBgn0014944 - gene - - - anon-99A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038548 CG17806 - http://flybase.org/reports/FBgn0038548 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604, InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003604, InterPro:IPR013087" - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG17806 "IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17806 11-Aug-17 DroID_v2017_08 "Drer\znf408, Drer\znfl2a, Drer\bcl6ab, Drer\LOC101883087" Scer\AZF1 "Cele\M03D4.4, Cele\lin-29, Cele\ztf-23, Cele\blmp-1, Cele\eor-1, Cele\Y55F3AM.14" - Mmus\Rbak "Hsap\ZKSCAN1, Hsap\ZNF514, Hsap\ZNF232, Hsap\ZNF789, Hsap\ZNF302, Hsap\ZNF18, Hsap\ZNF621, Hsap\ZNF75D, Hsap\ZNF3, Hsap\ZNF460, Hsap\ZNF10, Hsap\ZSCAN10, Hsap\ZNF517, Hsap\ZNF500, Hsap\ZNF274, Hsap\ZNF684, Hsap\ZNF263, Hsap\MZF1, Hsap\ZNF483, Hsap\ZNF547, Hsap\ZSCAN12, Hsap\ZSCAN31, Hsap\ZNF8, Hsap\ZNF620, Hsap\ZNF562, Hsap\ZFP69B, Hsap\ZSCAN22, Hsap\ZNF449, Hsap\ZNF641, Hsap\ZNF550, Hsap\ZNF202, Hsap\ZNF485, Hsap\ZSCAN16, Hsap\ZNF24, Hsap\ZNF205, Hsap\ZNF281, Hsap\ZNF735, Hsap\ZFP69, Hsap\ZSCAN20, Hsap\ZSCAN30, Hsap\ZNF444, Hsap\ZNF350, Hsap\ZIM3, Hsap\ZSCAN21, Hsap\ZNF669, Hsap\ZNF169, Hsap\GZF1, Hsap\ZSCAN1, Hsap\ZNF124, Hsap\ZNF354C, Hsap\ZNF566, Hsap\ZNF662, Hsap\ZKSCAN8, Hsap\ZNF101, Hsap\ZNF584, Hsap\ZNF582, Hsap\ZNF506, Hsap\ZNF557, Hsap\ZKSCAN5, Hsap\ZNF396, Hsap\ZNF251, Hsap\ZNF554, Hsap\ZNF649, Hsap\ZNF844, Hsap\ZNF806, Hsap\ZNF285, Hsap\ZNF197, Hsap\ZSCAN25, Hsap\ZKSCAN7, Hsap\ZNF213, Hsap\ZNF286A, Hsap\ZNF154, Hsap\ZKSCAN4, Hsap\ZNF829, Hsap\ZNF701, Hsap\ZNF773, Hsap\ZNF736, Hsap\ZSCAN26, Hsap\ZSCAN23, Hsap\ZNF19, Hsap\ZNF383, Hsap\ZFP92, Hsap\ZNF496, Hsap\ZNF574, Hsap\ZKSCAN3, Hsap\ZNF577, Hsap\ZNF140, Hsap\ZNF397, Hsap\ZNF2, Hsap\ZNF565" "viable,fertile" FBgn0082949 snoRNA:Me18S-U1356a snoRNA:Me18S-U1356a http://flybase.org/reports/FBgn0082949 snoRNA_gene - - - "snoRNA:Me18S-U1356a, Me18S-Um1356a, Me18S-U1356a, CR34644" - CR34644 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005054 fs(1)ne13 female sterile (1) no eggs 13 http://flybase.org/reports/FBgn0005054 - gene - - - "ne13, fs(1)ne[13], fs(1)ne13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "dorsal appendage,chorion,endochorion,oocyte" FBgn0260470 SP555 SP555 http://flybase.org/reports/FBgn0260470 protein_coding_gene molecular_function ; GO:0003674 | no biological data available intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001496 cellular_component ; GO:0005575 | no biological data available "dmSSBa, CG14041, NEST:bs13e02, BcDNA:AT09933, SP555" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001496:SOCS box domain, IPR001870:B30.2/SPRY domain, IPR003877:SPRY domain" CG14041 11-Aug-17 DroID_v2017_08 "Drer\spsb3a, Drer\spsb3b, Drer\si:dkey-23n7.10, Drer\ndufab1a, Drer\ndufab1b" - "Cele\madd-2, Cele\Y56A3A.19" "Xtro\LOC100497319, Xtro\spsb3, Xtro\ndufab1" "Mmus\Ndufab1, Mmus\Spsb3" Hsap\SPSB3 DRSC02367 E 0.249012002 1.134647573 1.527442319 0.407993433 0.210067434 -0.775739987 FBgn0038583 CG7183 - http://flybase.org/reports/FBgn0038583 protein_coding_gene - - - CG7183 IPR025066:Protein of unknown function DUF4078 CG7183 11-Aug-17 DroID_v2017_08 Drer\ccdc174 - Cele\C37A2.8 Xtro\ccdc174 Mmus\Ccdc174 Hsap\CCDC174 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0069924 CG41127 - http://flybase.org/reports/FBgn0069924 protein_coding_gene - - - CG41127 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002476 l(3)SG31 lethal (3) SG31 http://flybase.org/reports/FBgn0002476 FBgn0004718 gene - - - "l(3)2612, l(3)ds14, l(3)B14, l(3)SG31" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle,mitosis & nuclear chromosome,mitotic cell cycle" FBgn0032109 CG17005 - http://flybase.org/reports/FBgn0032109 protein_coding_gene - - - CG17005 IPR013783:Immunoglobulin-like fold CG17005 11-Aug-17 DroID_v2017_08 Drer\si:ch1073-349o24.2 - - Xtro\cfap65 Mmus\Ccdc108 Hsap\CFAP65 viable FBgn0086917 spok spookier http://flybase.org/reports/FBgn0086917 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from sequence model oxidoreductase activity ; GO:0016491 | inferred from sequence model" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available "CYP307A2, spok, Cyp307a2, Dmspok, 307a2p, Cyp307a2p, Cyp307a2Psi, CG40123, spo2, CG41624" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG41624 11-Aug-17 DroID_v2017_08 "Drer\cyp2k20, Drer\cyp2aa1, Drer\cyp2aa2, Drer\cyp2k31, Drer\cyp2r1, Drer\cyp2p8, Drer\cyp1a, Drer\cyp2k19, Drer\cyp2aa12, Drer\cyp1d1, Drer\cyp17a2, Drer\cyp2ad6, Drer\cyp2u1, Drer\cyp2k22, Drer\cyp2k17, Drer\cyp2aa3, Drer\cyp2aa11, Drer\cyp17a1, Drer\cyp2n13, Drer\cyp2x10.2, Drer\cyp2x9, Drer\cyp2x12, Drer\cyp21a2, Drer\cyp2p6, Drer\cyp2k18, Drer\cyp2k8, Drer\cyp2p7, Drer\cyp2aa8, Drer\cyp2j20, Drer\cyp2aa9, Drer\cyp2y3, Drer\si:zfos-411a11.2, Drer\cyp2k21, Drer\cyp2k16, Drer\cyp2x7, Drer\cyp2x8, Drer\cyp2ae1, Drer\cyp2aa4, Drer\LOC100148115, Drer\cyp2ad2, Drer\cyp1b1, Drer\si:dkey-286h2.7, Drer\cyp2x6" - Cele\cyp-33C2 "Xtro\LOC100145084, Xtro\LOC100493194, Xtro\cyp21a2.1, Xtro\cyp1b1, Xtro\LOC100145323, Xtro\LOC619584, Xtro\LOC100486127, Xtro\cyp2e1, Xtro\cyp2r1, Xtro\cyp2b6, Xtro\cyp2a6, Xtro\cyp2u1, Xtro\cyp2c8.2, Xtro\LOC100497460, Xtro\cyp2d6, Xtro\cyp2j2, Xtro\LOC100145695, Xtro\MGC107969, Xtro\cyp2a13, Xtro\LOC100145541, Xtro\LOC100036663, Xtro\cyp2c8.1, Xtro\cyp2w1, Xtro\cyp2f2, Xtro\cyp1a1, Xtro\cyp17a1, Xtro\LOC548374, Xtro\MGC69416, Xtro\LOC100497184, Xtro\cyp2g1p, Xtro\MGC69353, Xtro\cyp1d1" "Mmus\Cyp2c50, Mmus\Cyp2t4, Mmus\Cyp2d10, Mmus\Cyp2c55, Mmus\Cyp2c44, Mmus\Cyp2a22, Mmus\Cyp2d11, Mmus\Cyp2a4, Mmus\Cyp2j9, Mmus\Cyp2a5, Mmus\Cyp2c70, Mmus\Cyp2c54, Mmus\Cyp2j5, Mmus\Cyp2c38, Mmus\Cyp2ab1, Mmus\Cyp2d26, Mmus\Cyp2c69, Mmus\Cyp1a1, Mmus\Cyp2b19, Mmus\Cyp1a2, Mmus\Cyp2b10, Mmus\Cyp1b1, Mmus\Cyp2c29, Mmus\Cyp2d9, Mmus\Cyp21a1, Mmus\Cyp2c67, Mmus\Cyp17a1, Mmus\Cyp2f2, Mmus\Cyp2s1, Mmus\Cyp2c68, Mmus\Cyp2d40, Mmus\Cyp2j12, Mmus\Cyp2r1, Mmus\Cyp2e1, Mmus\Cyp2b9, Mmus\Cyp2c66, Mmus\Cyp2j8, Mmus\Cyp2c40, Mmus\Cyp2j11, Mmus\Cyp2w1, Mmus\Cyp2j13, Mmus\Cyp2d12, Mmus\Cyp2b13, Mmus\Cyp2u1, Mmus\Cyp2c39, Mmus\Cyp2a12, Mmus\Cyp2j6, Mmus\Cyp2c37, Mmus\Cyp2d22, Mmus\Cyp2c65, Mmus\Cyp2b23, Mmus\Cyp2g1, Mmus\Cyp2d34" "Hsap\CYP2A6, Hsap\CYP2S1, Hsap\CYP2B6, Hsap\CYP1A2, Hsap\CYP2C8, Hsap\CYP1B1, Hsap\CYP2C19, Hsap\CYP2A13, Hsap\CYP17A1, Hsap\CYP3A43, Hsap\CYP2D6, Hsap\CYP2F1, Hsap\CYP2R1, Hsap\CYP1A1, Hsap\CYP2E1, Hsap\CYP21A2, Hsap\CYP2W1, Hsap\CYP2J2, Hsap\CYP2C9, Hsap\CYP2U1, Hsap\CYP2C18, Hsap\CYP2A7" FBgn0062531 l(3)02727a lethal (3) 02727a http://flybase.org/reports/FBgn0062531 gene - - - "P02727, l(3)02727a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036023 CG18179 - http://flybase.org/reports/FBgn0036023 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP152, BEST:LP02275, CG18179" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG18179 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\zgc:112266" - - - "Mmus\C1s2, Mmus\C1s1" "Hsap\C1S, Hsap\PROC" viable FBgn0083149 S(smoDN)2629 Suppressor of smoDN 2629 http://flybase.org/reports/FBgn0083149 gene - - - S(smoDN)2629 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003090 pk prickle http://flybase.org/reports/FBgn0003090 "FBgn0003477, FBgn0033151, FBgn0040783" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781, InterPro:IPR010442 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P51140 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z7N9" positive regulation of axon extension ; GO:0045773 | inferred from genetic interaction with DAAM imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype anterior/posterior axis specification ; GO:0009948 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from mutant phenotype protein localization ; GO:0008104 | traceable author statement establishment of protein localization ; GO:0045184 | traceable author statement establishment of tissue polarity ; GO:0007164 | inferred from mutant phenotype maintenance of protein location ; GO:0045185 | traceable author statement establishment of planar polarity ; GO:0001736 | traceable author statement establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype morphogenesis of a polarized epithelium ; GO:0001738 | inferred from mutant phenotype axonal transport ; GO:0098930 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype positive regulation of axon guidance ; GO:1902669 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay membrane ; GO:0016020 | non-traceable author statement cytoplasm ; GO:0005737 | traceable author statement "sple, pk-sple, Pk, Pk-Sple, CG12830, CG11084, pk, Sple, pkM" "IPR001781:Zinc finger, LIM-type, IPR010442:PET domain, IPR033725:LIM1 prickle, IPR033727:LIM3 prickle, IPR033723:PET prickle, IPR033726:LIM2 prickle" CG11084 11-Aug-17 DroID_v2017_08 "Drer\prickle2b, Drer\prickle3, Drer\limch1a, Drer\prickle2a, Drer\lmo7b, Drer\fhl2a, Drer\limch1b, Drer\fhl1b, Drer\fhl3a, Drer\limd2, Drer\znf185, Drer\fhl2b, Drer\lmo7a, Drer\tes, Drer\fhl3b, Drer\fhl1a, Drer\prickle1b, Drer\prickle1a" "Scer\LRG1, Scer\RGA1, Scer\RGA2" "Cele\tes-1, Cele\lim-9, Cele\prkl-1" "Xtro\prickle2, Xtro\limch1, Xtro\fhl3, Xtro\prickle1, Xtro\lmcd1, Xtro\fhl1, Xtro\fhl2, Xtro\fhl5, Xtro\tes, Xtro\lmo7, Xtro\scel" "Mmus\Fhl3, Mmus\Prickle1, Mmus\Lmcd1, Mmus\Fhl1, Mmus\Tes, Mmus\Prickle4, Mmus\Limd2, Mmus\Prickle2, Mmus\Prickle3, Mmus\Fhl2, Mmus\Gm4907, Mmus\Fhl5, Mmus\Zfp185, Mmus\Lmo7, Mmus\Fhl4" "Hsap\FHL3, Hsap\PRICKLE1, Hsap\LMO7, Hsap\PRICKLE2, Hsap\LMCD1, Hsap\PRICKLE4, Hsap\ZNF185, Hsap\PRICKLE3, Hsap\FHL1, Hsap\FHL5, Hsap\LIMD2, Hsap\TES, Hsap\FHL2" " pupal stage | 28-34hr , embryonic stage , larval stage , larval stage | third instar " " wing

, ventral midline

, imaginal disc

, morphogenetic furrow | posterior to

, leg

, cephalic furrow

, dorsal mesothoracic disc

, eye disc

" "visible,recessive,planar polarity defective,visual behavior defective,viable,fertile,cell polarity defective,dominant,cell autonomous,somatic clone,cell non-autonomous,gravitaxis defective,cold sensitive" "ommatidium,tarsal segment 3,tarsal segment 4,tarsal segment 3 & joint,tarsal segment 4 & joint,eye,wing hair,leg & macrochaeta,leg & trichome,wing,scutum,abdomen,leg,joint,ectopic,abdominal tergite & macrochaeta,abdominal sternite & macrochaeta,tarsal segment,triple row,mesothoracic tergum & sensory mother cell & spindle,dorsal wing blade,trichome & costal cell,somatic clone,cell non-autonomous,cell autonomous,trichome & adult abdomen | somatic clone | cell autonomous,wing cell,eye photoreceptor cell,tarsal segment & joint,photoreceptor cell R4,precursor,tarsal segment 1 & joint,tarsal segment 2,abdomen & macrochaeta,trichome,metatarsus,posterior,thorax,wing & cell,anterior,wing & pupa & cellen-e16E,wing hair & cell & pupaen-e16E,tarsal segment 1 & jointda.G32,tarsal segment 1 & jointC-765,wing hair & 1st posterior cellptc-559.1,wing blade,trichome & adult abdomen | posterior compartment‘±Tub84B.PL,trichome & adult abdomen | somatic clone | posterior compartment‘±Tub84B.PL,trichome & adult abdomen" DRSC06178 E -0.938733806 -1.368047133 -1.118800096 2.026803618 0.859928835 1.384656696 FBgn0060828 l(3)S050910 lethal (3) S050910 http://flybase.org/reports/FBgn0060828 gene - - - "0509/10, l(3)S050910" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0038191 CG9925 - http://flybase.org/reports/FBgn0038191 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype - CG9925 "IPR002893:Zinc finger, MYND-type, IPR002999:Tudor domain" CG9925 11-Aug-17 DroID_v2017_08 - - - - Mmus\Tdgf1 Hsap\INHBB viable FBgn0028092 l(3)S079311b lethal (3) S079311b http://flybase.org/reports/FBgn0028092 gene - - - "0793/11, l(3)S079311, l(3)S079311b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037104 CG14574 - http://flybase.org/reports/FBgn0037104 protein_coding_gene - - - CG14574 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0025478 p40 p40 http://flybase.org/reports/FBgn0025478 - gene - - - p40 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046844 ird24 immune response deficient 24 http://flybase.org/reports/FBgn0046844 gene molecular_function ; GO:0003674 | no biological data available humoral immune response ; GO:0006959 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ird24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,immune response defective" FBgn0005051 fll flyless http://flybase.org/reports/FBgn0005051 - gene - - - fll - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0028866 CG18420 - http://flybase.org/reports/FBgn0028866 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH111, DS06874.6, BG:DS06874.6, CG18420" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG18420 11-Aug-17 DroID_v2017_08 "Drer\f7i, Drer\si:dkey-21e2.15, Drer\si:ch211-165b19.9, Drer\gzm3, Drer\si:dkey-21e2.12, Drer\si:dkey-21e2.7, Drer\si:ch211-165b19.5" - "Cele\try-3, Cele\try-6" - "Mmus\Mcpt4, Mmus\Klk6, Mmus\Gzmb, Mmus\Gzmg, Mmus\Cma2, Mmus\Mcpt1, Mmus\Gzmc, Mmus\Mcpt9, Mmus\Gzme, Mmus\Gzmd, Mmus\Ctsg, Mmus\Gzmf, Mmus\Mcpt8, Mmus\Cma1" "Hsap\CTSG, Hsap\GZMH, Hsap\GZMB, Hsap\CMA1" viable FBgn0250743 l(3)S113302 lethal (3) S113302 http://flybase.org/reports/FBgn0250743 gene - - - "l(3)S113302, l(3)s113302" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0020056 E(w[a])736 E(w[a])736 http://flybase.org/reports/FBgn0020056 - gene - - - "E736, E(w[a])736" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0082364 EP569 EP569 http://flybase.org/reports/FBgn0082364 gene - - - EP569 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0262210 mir-927 mir-927 stem loop http://flybase.org/reports/FBgn0262210 miRNA_gene - - - "miR-927, dme-mir-927, mir-927, MIR-927, CR42917" - CR42917 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,male,lethal - all die before end of P-stage,some die during pharate adult stage,visible,lethal - all die before end of larval stage,some die during larval stage" "eye,female,wing,wing margin" FBgn0000334 cml caramel http://flybase.org/reports/FBgn0000334 - gene - - - cml - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0001627 l(1)dn4 lethal (1) discs normal 4 http://flybase.org/reports/FBgn0001627 - gene - - - "l(1)d.norm.-4, l(1)dn4" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0028370 kek3 kekkon-3 http://flybase.org/reports/FBgn0028370 protein_coding_gene - - integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CT12629, BG:DS04862.1, CG4192, kek3" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR032675:Leucine-rich repeat domain, L domain-like, IPR013098:Immunoglobulin I-set, IPR003599:Immunoglobulin subtype" CG4192 11-Aug-17 DroID_v2017_08 "Drer\lrrc4.1, Drer\islr2, Drer\lrit1a, Drer\lrit1b, Drer\si:ch1073-303k11.2, Drer\LOC564748, Drer\slitrk6, Drer\lrit3a, Drer\lgi1a, Drer\lrrc4c, Drer\lrtm2a, Drer\lrit3b, Drer\lgi1b, Drer\lrrc4bb, Drer\lrit2, Drer\lrtm1, Drer\lrrc38b, Drer\lrrc24, Drer\lrrc4.2, Drer\si:dkey-52j6.3, Drer\LOC101882074, Drer\si:dkey-6l15.1, Drer\lrrc38a, Drer\lrtm2b" - "Cele\slt-1, Cele\iglr-2, Cele\iglr-3" "Xtro\lrtm2, Xtro\lrrc3, Xtro\flrt1, Xtro\lrrc4c, Xtro\slitrk1, Xtro\lrrc24, Xtro\lrit3, Xtro\lrit2, Xtro\lgi4, Xtro\lrrc52, Xtro\islr2" "Mmus\Lrrc24, Mmus\Lrrc26, Mmus\Tpbg, Mmus\Lrtm1, Mmus\Lrrc55, Mmus\Flrt2, Mmus\Lrit3, Mmus\Lrrn4, Mmus\Lrtm2, Mmus\Lrrc38, Mmus\Lrit1, Mmus\Lgi1, Mmus\Lrrc4, Mmus\Lrrn4cl, Mmus\Slitrk3, Mmus\Lrit2, Mmus\Islr, Mmus\Lrrc52, Mmus\Islr2, Mmus\Lrrc4c, Mmus\Lrrc4b" "Hsap\LRTM1, Hsap\LRRN4, Hsap\ISLR, Hsap\LRIT1, Hsap\LRRC38, Hsap\ISLR2, Hsap\LRRC52, Hsap\LRFN5, Hsap\LRRC26, Hsap\LRRC4B, Hsap\LRIT2, Hsap\LRFN3, Hsap\LGI1, Hsap\LRRC4C, Hsap\LRTM2, Hsap\LRRC55, Hsap\LRFN2, Hsap\FLRT2, Hsap\LRFN1, Hsap\LRIT3, Hsap\SLITRK3, Hsap\LRRC4, Hsap\LRFN4, Hsap\LRRC24, Hsap\LRRN4CL" viable FBgn0060506 l(3)S104903a lethal (3) S104903a http://flybase.org/reports/FBgn0060506 gene - - - "1049/03, l(3)S104903a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013402 anon-14Ba anon-14Ba http://flybase.org/reports/FBgn0013402 FBgn0014078 gene - - - anon-14Ba - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage FBgn0050148 CG30148 - http://flybase.org/reports/FBgn0050148 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR031756 - - "CG13429, BcDNA:AT18611, CG30148" "IPR031756:Beta-1,3-glucan-binding protein, N-terminal" CG30148 11-Aug-17 DroID_v2017_08 - - Cele\Y53H1B.4 - - - "viable,visible" trichogen cell FBgn0031431 CG3515 - http://flybase.org/reports/FBgn0031431 protein_coding_gene histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000458398 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000458398 histone H3-K4 trimethylation ; GO:0080182 | inferred from biological aspect of ancestor with PANTHER:PTN000458398 Set1C/COMPASS complex ; GO:0048188 | inferred from biological aspect of ancestor with PANTHER:PTN000458398 CG3515 "IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR011042:Six-bladed beta-propeller, TolB-like" CG3515 11-Aug-17 DroID_v2017_08 Drer\wdr82 Scer\SWD2 "Cele\swd-2.2, Cele\swd-2.1" Xtro\twf2 Mmus\Wdr82 Hsap\WDR82 viable FBgn0259399 EP-872 - http://flybase.org/reports/FBgn0259399 gene - - - EP-872 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0283480 Alp2 Alkaline phosphatase 2 http://flybase.org/reports/FBgn0283480 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 alkaline phosphatase activity ; GO:0004035 | inferred from direct assay dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 "Alp2, CG3290, Aph-2" "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG3290 11-Aug-17 DroID_v2017_08 "Drer\alpi.1, Drer\alpi.2, Drer\alpl, Drer\alp3" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1" "Mmus\Alpi, Mmus\Alppl2, Mmus\Alpl, Mmus\Akp3" "Hsap\ALPPL2, Hsap\ALPP, Hsap\ALPI, Hsap\ALPL" FBgn0038319 mRpL9 mitochondrial ribosomal protein L9 http://flybase.org/reports/FBgn0038319 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049636 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049636 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049636 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9BYD2 "L9, CG4923, CG31478, mRpL9" "IPR000244:Ribosomal protein L9, IPR009027:Ribosomal protein L9/RNase H1, N-terminal, IPR020070:Ribosomal protein L9, N-terminal" CG31478 11-Aug-17 DroID_v2017_08 Drer\mrpl9 - Cele\mrpl-9 - Mmus\Mrpl9 Hsap\MRPL9 "viable,fertile,visible,planar polarity defective" "trichogen cell,tormogen cell" FBgn0021833 l(2)k15819 lethal (2) k15819 http://flybase.org/reports/FBgn0021833 - gene - - - l(2)k15819 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035092 Nplp1 Neuropeptide-like precursor 1 http://flybase.org/reports/FBgn0035092 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | inferred from direct assay neuropeptide hormone activity ; GO:0005184 | non-traceable author statement receptor agonist activity ; GO:0048018 | inferred from physical interaction with Gyc76C neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement positive regulation of cGMP-mediated signaling ; GO:0010753 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement extracellular space ; GO:0005615 | inferred by curator from GO:0048018 "Nplp1, NPLP1, CG3441, IPNa, nplp1, MTYa, IPNamide, MTY-amide, NPLP-1, APK, VQQ, MTYamide" - CG3441 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC04370 K -0.125560189 0.05307003 1.217589562 0.567209623 -0.16942877 2.431181704 FBgn0266855 CR45316 - http://flybase.org/reports/FBgn0266855 non_protein_coding_gene - - - "CR45316, lincRNA.321" - CR45316 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0014960 fs(1)A1103 female sterile (1) A1103 http://flybase.org/reports/FBgn0014960 - gene - - - "fs(1)1103, fs(1)A1103" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065401 l(2)SH1603 lethal (2) SH1603 http://flybase.org/reports/FBgn0065401 gene - - - "l(2)SH1603, l(2)SH2 1603" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262520 l(3)psg1 lethal (3) persistent salivary gland 1 http://flybase.org/reports/FBgn0262520 gene - regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype - l(3)psg1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during P-stage" embryonic/larval salivary gland FBgn0265635 CR44442 - http://flybase.org/reports/FBgn0265635 non_protein_coding_gene - - - "CR44442, lincRNA.256" - CR44442 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082948 snoRNA:Me18S-U1356b snoRNA:Me18S-U1356b http://flybase.org/reports/FBgn0082948 snoRNA_gene - - - "snoRNA:Me18S-U1356b, Me18S-Um1356b, CR34645" - CR34645 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027150 l(3)70Ae lethal (3) 70Ae http://flybase.org/reports/FBgn0027150 - gene - - - "Ly-2, l(3)70Ae" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045857 e(Pi3K92E)beta e(Pi3K92E)beta http://flybase.org/reports/FBgn0045857 gene - - - "beta, e(Pi3K92E)beta" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000806 fs(1)de17 female sterile (1) defective eggs 17 http://flybase.org/reports/FBgn0000806 - gene - - - "de17, fs(1)de17" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "endochorion,dorsal appendage" FBgn0265528 CR44378 - http://flybase.org/reports/FBgn0265528 non_protein_coding_gene - - - "CR44378, lincRNA.326" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085451 htk hat-trick http://flybase.org/reports/FBgn0085451 protein_coding_gene transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000359478 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000359478 negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype Sin3-type complex ; GO:0070822 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG7274, CG7282, ARID4B, CG34422, Q9VWP3_DROME, htk" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR000953:Chromo/chromo shadow domain, IPR016197:Chromo domain-like, IPR025995:RNA binding activity-knot of a chromodomain, IPR012603:RBB1NT, IPR001606:ARID DNA-binding domain, IPR002999:Tudor domain" CG34422 11-Aug-17 DroID_v2017_08 "Drer\tomm20a, Drer\zgc:77151, Drer\arid4a, Drer\arid3a, Drer\arid5b, Drer\arid3c, Drer\arid4b, Drer\arid5b, Drer\arid3b, Drer\arid5a" "Scer\SWI1, Scer\RSC9, Scer\ECM5" "Cele\cfi-1, Cele\arid-1" "Xtro\arid4b, Xtro\arid4a, Xtro\arid5b, Xtro\arid3a" "Mmus\Arid5b, Mmus\Arid4a, Mmus\Arid2, Mmus\Arid5a, Mmus\Arid3a, Mmus\Ncoa6, Mmus\Arid4b, Mmus\Arid3b, Mmus\Arid3c" "Hsap\RBM34, Hsap\ARID2, Hsap\ARID5B, Hsap\ARID3A, Hsap\ARID3B, Hsap\ARID4A, Hsap\ARID3C, Hsap\ARID5A, Hsap\ARID4B" "visible,viable,partially lethal - majority die" "wing,trichogen cell" DRSC20031 IE -2.046217144 0.653269786 -1.990817488 0.187659604 0.774209984 1.443258322 FBgn0260335 GSd452 - http://flybase.org/reports/FBgn0260335 gene - - - GSd452 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0029834 CG5937 - http://flybase.org/reports/FBgn0029834 protein_coding_gene ARF guanyl-nucleotide exchange factor activity ; GO:0005086 | inferred from electronic annotation with InterPro:IPR000904 regulation of ARF protein signal transduction ; GO:0032012 | inferred from electronic annotation with InterPro:IPR000904 - CG5937 "IPR000904:Sec7 domain, IPR016024:Armadillo-type fold, IPR015403:Sec7, C-terminal, IPR023394:Sec7 domain, alpha orthogonal bundle" CG5937 11-Aug-17 DroID_v2017_08 "Drer\arfgef3, Drer\si:ch211-150i13.1, Drer\psd3l, Drer\psd2" "Scer\BOI2, Scer\SYT1" "Cele\efa-6, Cele\T20F10.5, Cele\Y106G6G.2, Cele\Y106G6G.6" - "Mmus\Psd4, Mmus\Psd, Mmus\Psd2, Mmus\Arfgef3, Mmus\Psd3" "Hsap\ARFGEF3, Hsap\PSD, Hsap\PSD2, Hsap\PSD4, Hsap\PSD3" "viable,visible" "chaeta,supernumerary" FBgn0039590 CG10011 - http://flybase.org/reports/FBgn0039590 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN001192552 retrograde transport, endosome to plasma membrane ; GO:1990126 | inferred from biological aspect of ancestor with PANTHER:PTN001192553" cellular_component ; GO:0005575 | no biological data available CG10011 "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG10011 11-Aug-17 DroID_v2017_08 "Drer\zgc:172215, Drer\si:dkey-145p14.5" Scer\AVO2 Cele\T28D6.4 Xtro\ankrd50 "Mmus\Ankrd50, Mmus\Cttnbp2" "Hsap\CTTNBP2, Hsap\ANKRD50" "viable,fertile" FBgn0262981 CR43289 - http://flybase.org/reports/FBgn0262981 non_protein_coding_gene - - - "CG43289, CR43289" - CR43289 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015466 l(2)44Fa lethal (2) 44Fa http://flybase.org/reports/FBgn0015466 - gene - - - l(2)44Fa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive" FBgn0262513 Vha16-4 Vacuolar H[+] ATPase 16kD subunit 4 http://flybase.org/reports/FBgn0262513 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from sequence model proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000813763" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR002379, InterPro:IPR011555 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model lysosomal lumen acidification ; GO:0007042 | inferred from biological aspect of ancestor with PANTHER:PTN000813819" "vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000000753 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model" "vha16-4, CG9013, Vha16-4" "IPR000245:V-ATPase proteolipid subunit, IPR002379:V-ATPase proteolipid subunit C-like domain, IPR011555:V-ATPase proteolipid subunit C, eukaryotic" CG9013 11-Aug-17 DroID_v2017_08 "Drer\atp6v0ca, Drer\atp6v0cb" "Scer\VMA11, Scer\VMA3" "Cele\vha-3, Cele\vha-1, Cele\vha-2" Xtro\atp6v0c Mmus\Atp6v0c Hsap\ATP6V0C FBgn0001803 l(1)Mc28 lethal (1) Mc28 http://flybase.org/reports/FBgn0001803 - gene - - - l(1)Mc28 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "macrochaeta,somatic clone,wing hair" FBgn0060556 l(3)S097406b lethal (3) S097406b http://flybase.org/reports/FBgn0060556 gene - - - "0974/06, l(3)S097406b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0066318 26D19 26D19 http://flybase.org/reports/FBgn0066318 gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 26D19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval mushroom body,somatic clone" FBgn0043019 ttk::Hsap\BCL6 BCL6 http://flybase.org/reports/FBgn0043019 engineered_fusion_gene - - - ttk::Hsap\BCL6 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,ommatidium,photoreceptor cell R7,eye photoreceptor cell" FBgn0260589 2L3189 - http://flybase.org/reports/FBgn0260589 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3189 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0004016 wk weak http://flybase.org/reports/FBgn0004016 - gene - - - wk - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,reduced" "wing,abdomen,macrochaeta" FBgn0051026 CR31026 - http://flybase.org/reports/FBgn0051026 non_protein_coding_gene - - - CR31026 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027506 EDTP Egg-derived tyrosine phosphatase http://flybase.org/reports/FBgn0027506 FBgn0062229 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 phosphatidylinositol-3-phosphatase activity ; GO:0004438 | inferred from biological aspect of ancestor with PANTHER:PTN000338419 dephosphorylation ; GO:0016311 | inferred from electronic annotation with InterPro:IPR016130 oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "D-EDTP, CG6542, BcDNA:LD23181, anon-WO0118547.124, EDTP" "IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR010569:Myotubularin-like phosphatase domain" CG6542 11-Aug-17 DroID_v2017_08 Drer\mtmr14 - - Xtro\mtmr14 Mmus\Mtmr14 Hsap\MTMR14 "viable,fertile,lethal,recessive,some die during embryonic stage" "ovary,germline clone" FBgn0013685 mt:ND6 mitochondrial NADH-ubiquinone oxidoreductase chain 6 http://flybase.org/reports/FBgn0013685 FBgn0002867 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR001457 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001457 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001687626 "CG34089, ND6, URF6, mt:ND6, nd6, nad6" "IPR001457:NADH:ubiquinone/plastoquinone oxidoreductase, chain 6" CG34089 11-Aug-17 DroID_v2017_08 Drer\ND6 - - - Mmus\ND6 Hsap\ND6 FBgn0000284 cf cleft http://flybase.org/reports/FBgn0000284 - gene - - - cf - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile" "wing,crossvein,wing vein L4" FBgn0003897 tur turnip http://flybase.org/reports/FBgn0003897 - gene - olfactory learning ; GO:0008355 | traceable author statement - tur - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,memory defective" FBgn0264994 CR44145 - http://flybase.org/reports/FBgn0264994 non_protein_coding_gene - - - CR44145 - CR44145 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060796 l(3)S058004b lethal (3) S058004b http://flybase.org/reports/FBgn0060796 gene - - - "0580/04, l(3)S058004b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0029531 CG13362 - http://flybase.org/reports/FBgn0029531 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13362 - CG13362 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0015938 fits fades in the stretch http://flybase.org/reports/FBgn0015938 - gene - - - fits - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262116 RNASEK Ribonuclease kappa http://flybase.org/reports/FBgn0262116 protein_coding_gene endoribonuclease activity ; GO:0004521 | inferred from sequence or structural similarity with UniProtKB:Q6P5S7 endoribonuclease activity ; GO:0004521 | inferred from biological aspect of ancestor with PANTHER:PTN002421559 rRNA transcription ; GO:0009303 | inferred from sequence or structural similarity with UniProtKB:Q6P5S7 cellular response to virus ; GO:0098586 | inferred from mutant phenotype rRNA transcription ; GO:0009303 | inferred from biological aspect of ancestor with PANTHER:PTN002421559 - "l(2)NC110, GM16138, anon-EST:Posey156, BcDNA:GM16138, NC110, RNASEK, dRNASEK, CG40127" IPR026770:Ribonuclease kappa CG40127 11-Aug-17 DroID_v2017_08 "Drer\rnasekb, Drer\rnaseka" Scer\YPR170W-B "Cele\F49C12.12, Cele\C46G7.1" Xtro\rnasek Mmus\Rnasek Hsap\RNASEK "lethal,recessive" DRSC21641 IE -0.292381395 -1.824657266 -0.246721731 -1.78561779 -0.538696196 0.000388191 FBgn0266932 CR45383 - http://flybase.org/reports/FBgn0266932 non_protein_coding_gene - - - CR45383 - CR45383 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040616 CG12871 - http://flybase.org/reports/FBgn0040616 protein_coding_gene - - - CG12871 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040363 CG11384 - http://flybase.org/reports/FBgn0040363 protein_coding_gene - - - "EG:BACR42I17.3, CG11384" IPR008166:Glycosyltransferase family 92 CG11384 11-Aug-17 DroID_v2017_08 "Drer\zgc:194839, Drer\si:dkey-56i24.1, Drer\si:ch73-211l2.1, Drer\si:zfos-464b6.2" - "Cele\C18G1.7, Cele\F49C12.5, Cele\K06H6.4, Cele\F36F12.3, Cele\T06A1.5, Cele\C01G5.9, Cele\ZK1025.4, Cele\F28H7.7, Cele\C14C6.8, Cele\F13G3.3, Cele\F46F5.7, Cele\C31B8.7, Cele\C17A2.2, Cele\ZK488.5, Cele\C14C6.6, Cele\ZK488.6, Cele\Y47D3B.4, Cele\galt-1, Cele\T06A1.1, Cele\C49A1.5, Cele\T05B11.4, Cele\Y105C5B.25, Cele\D1014.5" "Xtro\LOC100145503, Xtro\LOC100495879, Xtro\LOC100492375" - - FBgn0038281 RpL10Aa Ribosomal protein L10Aa http://flybase.org/reports/FBgn0038281 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR002143 structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002143 neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 cytoplasmic translation ; GO:0002181 | traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype large ribosomal subunit ; GO:0015934 | inferred from electronic annotation with InterPro:IPR002143 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG3843, BcDNA:AT11516, RpL10Aa, Rpl10Aa" "IPR002143:Ribosomal protein L1, IPR016095:Ribosomal protein L1, 3-layer alpha/beta-sandwich, IPR028364:Ribosomal protein L1/ribosomal biogenesis protein, IPR023674:Ribosomal protein L1-like" CG3843 11-Aug-17 DroID_v2017_08 Drer\rpl10a "Scer\TOS4, Scer\RPL1A, Scer\RPL1B" "Cele\mrpl-1, Cele\rpl-1" Xtro\rpl10a Mmus\Rpl10a Hsap\RPL10A "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC15518 EK -0.513803554 -1.207790896 0.325754437 -1.5958244 0.55805702 1.646782289 FBgn0002339 l(3)87Bh lethal (3) 87Bh http://flybase.org/reports/FBgn0002339 - gene - - - "ck20, l(3)ck20, l(3)87Bh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0053159 CG33159 - http://flybase.org/reports/FBgn0053159 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP176, CG11532, CG33159" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG33159 11-Aug-17 DroID_v2017_08 "Drer\zgc:55888, Drer\st14a, Drer\zmp:0000001114, Drer\tmprss9" - Cele\try-1 - "Mmus\St14, Mmus\Gzmm, Mmus\Prss55, Mmus\Tmprss13, Mmus\Gzma" "Hsap\PRSS57, Hsap\ST14, Hsap\GZMM, Hsap\GZMA, Hsap\TMPRSS13" FBgn0036899 tey teyrha-meyrha http://flybase.org/reports/FBgn0036899 protein_coding_gene - "protein ubiquitination ; GO:0016567 | inferred from electronic annotation with InterPro:IPR031824 positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from electronic annotation with InterPro:IPR031824 synaptic target recognition ; GO:0008039 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "CG8780, tey" "IPR031824:E3 ubiquitin-protein ligase RNF220, middle domain" CG8780 11-Aug-17 DroID_v2017_08 "Drer\rnf220b, Drer\rnf220a" - - - Mmus\Rnf220 Hsap\RNF220 "visible,lethal,neuroanatomy defective,viable" "costal cell,distal costal vein,medial costal vein,wing vein,ectopic,eye,abdominal segment motor neuron,A1-7 ventral longitudinal muscle 1" FBgn0001853 l(1)tsUC19 lethal (1) tsUC19 http://flybase.org/reports/FBgn0001853 - gene - - - l(1)tsUC19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0039369 CG17195 - http://flybase.org/reports/FBgn0039369 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG17195, CG17195-PA" "IPR001594:Palmitoyltransferase, DHHC domain" CG17195 11-Aug-17 DroID_v2017_08 "Drer\zdhhc18a, Drer\zgc:77880, Drer\zdhhc5a, Drer\zdhhc8b, Drer\zdhhc1, Drer\zdhhc12a, Drer\LOC100334198, Drer\zdhhc12b, Drer\zdhhc20b, Drer\zdhhc20a, Drer\zdhhc22, Drer\zdhhc9, Drer\zdhhc7, Drer\zdhhc3a, Drer\zdhhc23a, Drer\zdhhc5b, Drer\zdhhc23b, Drer\zdhhc14, Drer\zdhhc21, Drer\zdhhc3b, Drer\zdhhc24" "Scer\ERF2, Scer\PFA5" "Cele\dhhc-12, Cele\dhhc-1, Cele\dhhc-9, Cele\dhhc-10" "Xtro\dnz1, Xtro\zdhhc8, Xtro\zdhhc14, Xtro\zdhhc12, Xtro\zdhhc21, Xtro\zdhhc9, Xtro\zdhhc24, Xtro\zdhhc1, Xtro\zdhhc3, Xtro\zdhhc7" "Mmus\Zdhhc21, Mmus\Zdhhc19, Mmus\Zdhhc5, Mmus\Zdhhc24, Mmus\Zdhhc22, Mmus\Zdhhc11, Mmus\Zdhhc1, Mmus\Zdhhc23, Mmus\Zdhhc8, Mmus\Zdhhc20, Mmus\Zdhhc7, Mmus\Zdhhc25, Mmus\Zdhhc12, Mmus\Zdhhc14, Mmus\Zdhhc9, Mmus\Zdhhc18, Mmus\Zdhhc3" "Hsap\ZDHHC19, Hsap\ZDHHC9, Hsap\ZDHHC22, Hsap\ZDHHC23, Hsap\ZDHHC21, Hsap\ZDHHC11, Hsap\ZDHHC7, Hsap\ZDHHC14, Hsap\ZDHHC24, Hsap\ZDHHC5, Hsap\ZDHHC1, Hsap\ZDHHC12, Hsap\ZDHHC3, Hsap\ZDHHC20, Hsap\ZDHHC18, Hsap\ZDHHC8" "partially lethal - majority die,some die during pupal stage" FBgn0040121 l(2)23Dc lethal (2) 23Dc http://flybase.org/reports/FBgn0040121 gene - - - "l(2)23Ca, l(2)23Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0058250 CG40250 - http://flybase.org/reports/FBgn0058250 protein_coding_gene - - - CG40250 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030301 HP5 Heterochromatin protein 5 http://flybase.org/reports/FBgn0030301 protein_coding_gene - - chromocenter ; GO:0010369 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay "HP5, CG1745" - CG1745 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,suppressor of variegation,dominant" FBgn0000219 bright bright http://flybase.org/reports/FBgn0000219 - gene - - - "bri, bright" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" "eye,pigment cell,Malpighian tubule" FBgn0038851 dmrt93B doublesex-Mab related 93B http://flybase.org/reports/FBgn0038851 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR026607 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001275" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001275, InterPro:IPR026607" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026607 "dmrt93b, CG5737, dmrt93B" "IPR001275:DM DNA-binding domain, IPR005173:DMRTA motif, IPR026607:DMRT/protein doublesex/protein male abnormal 3" CG5737 11-Aug-17 DroID_v2017_08 "Drer\dmrt2a, Drer\dmrt2b, Drer\dmrta2, Drer\dmrt3a" - "Cele\dmd-10, Cele\dmd-6, Cele\dmd-9, Cele\dmd-3, Cele\dmd-5, Cele\dmd-7, Cele\dmd-4, Cele\dmd-8, Cele\mab-3" "Xtro\dmrt3, Xtro\dmrta1, Xtro\kank1, Xtro\dmrta2" "Mmus\Dmrt2, Mmus\Dmrtc2, Mmus\Dmrtc1b, Mmus\Dmrta2, Mmus\Dmrtc1c1, Mmus\Dmrt3, Mmus\Dmrtc1a, Mmus\Dmrta1, Mmus\Dmrtc1c2, Mmus\Dmrtb1, Mmus\Dmrt1" "Hsap\DMRT1, Hsap\DMRTA1, Hsap\DMRTC1, Hsap\DMRTB1, Hsap\DMRT2, Hsap\DMRT3, Hsap\DMRTA2, Hsap\DMRTC1B, Hsap\DMRTC2" viable FBgn0022960 vimar visceral mesodermal armadillo-repeats http://flybase.org/reports/FBgn0022960 "FBgn0021806, FBgn0027729" protein_coding_gene - rhabdomere development ; GO:0042052 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay positive regulation of neuron death ; GO:1901216 | inferred from genetic interaction with Fmr1 plasma membrane ; GO:0005886 | inferred from direct assay "l(2)k16722, anon-EST:Posey213, CG3572, vimar, Vimar" "IPR000225:Armadillo, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG3572 11-Aug-17 DroID_v2017_08 "Drer\rap1gds1, Drer\si:dkey-21e13.3, Drer\si:dkey-191g9.5" "Scer\BEM4, Scer\VAC8" Cele\ima-2 Xtro\rap1gds1 Mmus\Rap1gds1 Hsap\RAP1GDS1 " embryonic stage | stage 1-4 , larval stage | first instar , embryonic stage--larval stage , adult stage | female , embryonic stage | stage 9-17 " organism

"viable,fertile,lethal,recessive" FBgn0000300 cgd congested http://flybase.org/reports/FBgn0000300 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available cgd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,embryonic/larval midgut" FBgn0039053 CG6738 - http://flybase.org/reports/FBgn0039053 protein_coding_gene aminoacylase activity ; GO:0004046 | inferred from electronic annotation with InterPro:IPR010159 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010159 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010159 CG6738 "IPR002933:Peptidase M20, IPR010159:N-acyl-L-amino-acid amidohydrolase, IPR011650:Peptidase M20, dimerisation domain" CG6738 11-Aug-17 DroID_v2017_08 "Drer\LOC100001620, Drer\pm20d1.1, Drer\pm20d1.2, Drer\acy1" Scer\CPS1 "Cele\C10C5.4, Cele\C10C5.3, Cele\C10C5.5, Cele\C06A6.4" "Xtro\acy1.1, Xtro\pm20d1" "Mmus\Pm20d1, Mmus\Acy1" "Hsap\ABHD14A-ACY1, Hsap\PM20D1, Hsap\ABHD14A, Hsap\ACY1" viable FBgn0005741 l(1)TK233 lethal (1) TK233 http://flybase.org/reports/FBgn0005741 - gene - - - "l233, l(1)TK233" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065394 l(2)SH1622 lethal (2) SH1622 http://flybase.org/reports/FBgn0065394 gene - - - "l(2)SH1622, l(2)SH2 1622" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010097 gammaTub37C gamma-Tubulin at 37C http://flybase.org/reports/FBgn0010097 FBgn0001003 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity GTP binding ; GO:0005525 | inferred from direct assay" cytoplasmic microtubule organization ; GO:0031122 | inferred from electronic annotation with InterPro:IPR002454 microtubule nucleation ; GO:0007020 | inferred from electronic annotation with InterPro:IPR002454 oocyte nucleus localization involved in oocyte dorsal/ventral axis specification ; GO:0051663 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation ; GO:0051316 | inferred from mutant phenotype spindle assembly involved in female meiosis I ; GO:0007057 | inferred from mutant phenotype "gamma-tubulin complex ; GO:0000930 | inferred from electronic annotation with InterPro:IPR002454 microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR017975 cytoplasm ; GO:0005737 | inferred from direct assay microtubule ; GO:0005874 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay meiotic spindle ; GO:0072687 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay" "gamma-tubulin, GTU88*, gamma tubulin, gamma-Tub, gamma-Tub37C, Rb1011, fs(2)TW1, g-Tubulin, gammaTUB, CG17566, D.m.GAMMA-37C, gammaTub37CD, gamma Tub37CD, gammaTUB37C, PL10, TW1, fsTW1, gamma[mat], fs(2)TWI, gammaTub37C, gammaTub2, gammatub, gammaTub, gamma-tub37CD, gamma-tub37C, gammaTub37c, Tub3B, gamma-tub" "IPR000217:Tubulin, IPR002454:Gamma tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain" CG17566 11-Aug-17 DroID_v2017_08 "Drer\tubg1, Drer\tubd1" Scer\TUB4 "Cele\tba-8, Cele\tbb-1, Cele\tbg-1" "Xtro\tubz1, Xtro\tubg1, Xtro\tubd1" "Mmus\Tubd1, Mmus\Tubg2, Mmus\Tubg1" "Hsap\TUBG1, Hsap\TUBG2, Hsap\TUBD1" "female sterile,recessive,male fertile,meiotic cell cycle defective,wild-type,mitotic cell cycle defective,maternal effect,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,viable" "condensed nuclear chromosome,meiotic spindle,oocyte nucleus,meiotic metaphase I,cleavage stage embryo,spindle,centrosome | maternal effectTE37C-7),polar body nucleus,oocyte,nucleus,spindle & oocyte,egg & spindleTE37C-7),condensed nuclear chromosomeExel6043),meiotic spindleExel6043),spindle | cleavage stage | maternal effect,spindle | embryonic stage,aster | embryonic stage,embryo & mitosis & nuclear chromosome,maternal effect,spindle | maternal effectTE37C-7),ovariole,germline clone" FBgn0065681 l(2)SH0664 lethal (2) SH0664 http://flybase.org/reports/FBgn0065681 gene - - - "l(2)SH0664, l(2)SH2 0664" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022747 anon-E9 anon-E9 http://flybase.org/reports/FBgn0022747 - gene - - - "E9, anon-E9" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003115 plw pale wing http://flybase.org/reports/FBgn0003115 - gene - - - plw - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,poor,body color defective" "wing,macrochaeta" FBgn0004148 l(2)57Ab lethal (2) 57Ab http://flybase.org/reports/FBgn0004148 - gene - - - l(2)57Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,recessive" FBgn0283437 PPO1 Prophenoloxidase 1 http://flybase.org/reports/FBgn0283437 protein_coding_gene monophenol monooxygenase activity ; GO:0004503 | inferred from direct assay catechol oxidase activity ; GO:0004097 | inferred from direct assay L-DOPA monooxygenase activity ; GO:0036263 | inferred from direct assay dopamine monooxygenase activity ; GO:0036264 | inferred from direct assay melanization defense response ; GO:0035006 | inferred from mutant phenotype dopamine metabolic process ; GO:0042417 | inferred by curator from GO:0036264 response to wounding ; GO:0009611 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype inferred from genetic interaction with PPO2 scab formation ; GO:0035314 | inferred from mutant phenotype melanization defense response ; GO:0035006 | traceable author statement defense response to fungus ; GO:0050832 | inferred from mutant phenotype inferred from genetic interaction with PPO2 sleep ; GO:0030431 | inferred from expression pattern melanization defense response ; GO:0035006 | inferred from mutant phenotype inferred from genetic interaction with PPO2 hemolymph coagulation ; GO:0042381 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay "PPO1, DoxA1, Bc, CG42639, CG5779, proPO54, Propo, proPO, PO, PPO, A1, Mox, Dox-A1, DmePPOA1, A[[1]], i12, proPO A[[1]], pro-A, pro-POA[[1]], pro-PO, PO A1, ProPO A1, Phox, ProPO, ProPo, ProPO54, PO54, proPO-A1, bc, PPO-1, PROPO-A1" "IPR014756:Immunoglobulin E-set, IPR013788:Hemocyanin/hexamerin, IPR005204:Hemocyanin, N-terminal, IPR000896:Hemocyanin/hexamerin middle domain, IPR008922:Uncharacterised domain, di-copper centre, IPR002227:Tyrosinase copper-binding domain, IPR005203:Hemocyanin, C-terminal" CG42639 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0087041 CG42231 - http://flybase.org/reports/FBgn0087041 protein_coding_gene - - - CG42231 - CG42231 11-Aug-17 DroID_v2017_08 Drer\si:dkey-23f9.4 - - - Mmus\Hyls1 - FBgn0054049 CG34049 - http://flybase.org/reports/FBgn0054049 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR018244 cellular_component ; GO:0005575 | no biological data available "BP1065, CG34049" "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR018244:Allergen V5/Tpx-1-related, conserved site, IPR034113:Golgi-associated plant pathogenesis-related protein 1, SCP domain" CG34049 11-Aug-17 DroID_v2017_08 "Drer\pi15a, Drer\crispld2, Drer\r3hdml, Drer\crispld1b, Drer\pi15b, Drer\crispld1a, Drer\glipr1b, Drer\glipr2, Drer\LOC100536500, Drer\glipr2l" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\D2062.1, Cele\C07A4.2, Cele\F09B9.5, Cele\C07A4.3" "Xtro\crisp2, Xtro\crisp3, Xtro\crispld2, Xtro\r3hdml, Xtro\glipr2, Xtro\MGC108118, Xtro\crisp1" "Mmus\Pi15, Mmus\Crispld2, Mmus\Glipr2, Mmus\Glipr1l2, Mmus\Clec18a, Mmus\Crisp1, Mmus\Crisp4, Mmus\Crispld1, Mmus\Crisp3, Mmus\Glipr1, Mmus\Pi16, Mmus\Glipr1l1, Mmus\R3hdml, Mmus\Crisp2" "Hsap\CLEC18B, Hsap\CRISPLD1, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\PI16, Hsap\PI15, Hsap\CLEC18C, Hsap\CRISP1, Hsap\GLIPR1, Hsap\CLEC18A, Hsap\R3HDML, Hsap\GLIPR2, Hsap\CRISP2, Hsap\GLIPR1L1" FBgn0259378 C865 - http://flybase.org/reports/FBgn0259378 gene - - - C865 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0264841 CR44049 - http://flybase.org/reports/FBgn0264841 non_protein_coding_gene - - - CR44049 - CR44049 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263385 CR43437 - http://flybase.org/reports/FBgn0263385 non_protein_coding_gene - - - CR43437 - CR43437 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267863 CR46151 - http://flybase.org/reports/FBgn0267863 pseudogene_attribute - - - CR46151 - CR46151 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051119 HDAC11 Histone deacetylase 11 http://flybase.org/reports/FBgn0051119 protein_coding_gene histone deacetylase activity ; GO:0004407 | inferred from sequence or structural similarity with UniProtKB:Q96DB2 - - "dmHDA403, DHDACX, CG31119, HDAC11, HDACX, dHDAC11, HdacX, Hdac11" "IPR000286:Histone deacetylase superfamily, IPR023801:Histone deacetylase domain" CG31119 11-Aug-17 DroID_v2017_08 Drer\hdac11 "Scer\HOS2, Scer\HOS1" "Cele\hda-11, Cele\moc-3" Xtro\mocs3 "Mmus\Hdac11, Mmus\Mocs3" "Hsap\HDAC11, Hsap\MOCS3" FBgn0020893 Su(osk)K2 Suppressor of oskar K2 http://flybase.org/reports/FBgn0020893 - gene - - - "K2, Su(osk)K2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002628 M(3)100CF Minute (3) 100CF http://flybase.org/reports/FBgn0002628 - gene - - - "M(3)f, M(3)100CF" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,Minute,dominant,visible" macrochaeta FBgn0260347 GSd456 - http://flybase.org/reports/FBgn0260347 gene - - - GSd456 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000703 fltI flight defective I http://flybase.org/reports/FBgn0000703 - gene - - - fltI - - 11-Aug-17 DroID_v2017_08 - - - - - - flight defective FBgn0051128 CG31128 - http://flybase.org/reports/FBgn0051128 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT04449, CG31128" - CG31128 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC13675 K 0.643136191 0.129282895 0.031972839 0.647969477 5.545474686 0.590315916 FBgn0261356 CG42633 - http://flybase.org/reports/FBgn0261356 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42633, CG6547" - CG42633 11-Aug-17 DroID_v2017_08 - - - - - - DRSC16061 K 0.202706458 0.381547892 1.011542126 -0.114301083 0.588897376 -1.708518502 FBgn0266419 CR45059 - http://flybase.org/reports/FBgn0266419 non_protein_coding_gene - - - CR45059 - CR45059 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035578 CG13707 - http://flybase.org/reports/FBgn0035578 protein_coding_gene - - - CG13707 - CG13707 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051231 CG31231 - http://flybase.org/reports/FBgn0051231 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GH08511, BcDNA:AT20662, anon-WO0140519.92, CG31231" IPR025254:Domain of unknown function DUF4201 CG31231 11-Aug-17 DroID_v2017_08 - - - - Mmus\Ccdc96 - "partially lethal - majority die,some die during pupal stage" FBgn0267304 CR45740 - http://flybase.org/reports/FBgn0267304 non_protein_coding_gene - - - CR45740 - CR45740 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024228 hopR-90E hop-responsive-90E http://flybase.org/reports/FBgn0024228 - gene - - - hopR-90E - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011161 l(1)Q240 lethal (1) Q240 http://flybase.org/reports/FBgn0011161 FBgn0010210 gene - - - l(1)Q240 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031713 CG7277 - http://flybase.org/reports/FBgn0031713 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen ; GO:0016709 | inferred from electronic annotation with InterPro:IPR010971, InterPro:IPR018168 FAD binding ; GO:0071949 | inferred from electronic annotation with InterPro:IPR002938" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000689, InterPro:IPR010971, InterPro:IPR018168, InterPro:IPR023753 ubiquinone biosynthetic process ; GO:0006744 | inferred from electronic annotation with InterPro:IPR010971" - CG7277 "IPR000689:Ubiquinone biosynthesis monooxygenase COQ6, IPR002938:FAD-binding domain, IPR010971:Ubiquinone biosynthesis hydroxylase UbiH/COQ6, IPR018168:Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site, IPR023753:FAD/NAD(P)-binding domain" CG7277 11-Aug-17 DroID_v2017_08 Drer\coq6 Scer\COQ6 Cele\coq-6 Xtro\coq6 Mmus\Coq6 Hsap\COQ6 viable FBgn0033927 CR10102 - http://flybase.org/reports/FBgn0033927 pseudogene_attribute - - - "CG10102, CR10102, dArc3, Arc3" - CR10102 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,hyperactive,conditional,chemical resistant" DRSC05963 I -0.693321263 -1.649586046 -0.156981717 -0.806360034 -0.613843433 0.264347466 FBgn0032822 CG10466 - http://flybase.org/reports/FBgn0032822 protein_coding_gene first spliceosomal transesterification activity ; GO:0000384 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000567094 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000566842 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000567094 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000567094" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000567094 RES complex ; GO:0070274 | inferred from biological aspect of ancestor with PANTHER:PTN000567094 "cg10466, anon-WO0140519.255, CG10466" IPR000504:RNA recognition motif domain CG10466 11-Aug-17 DroID_v2017_08 Drer\rbmx2 Scer\IST3 Cele\C30B5.4 Xtro\rbmx2 Mmus\Rbmx2 Hsap\RBMX2 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0043482 l(3)66EFd lethal (3) 66EFd http://flybase.org/reports/FBgn0043482 gene - - - l(3)66EFd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263630 mir-3641 mir-3641 stem loop http://flybase.org/reports/FBgn0263630 miRNA_gene - - - "mir-3641, CR43520" - CR43520 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002126 l(2)IIJ59 lethal (2) IIJ59 http://flybase.org/reports/FBgn0002126 - gene - - - l(2)IIJ59 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0019775 l(1)36 lethal (1) 36 http://flybase.org/reports/FBgn0019775 - gene - - - l(1)36 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267293 CR45729 - http://flybase.org/reports/FBgn0267293 non_protein_coding_gene - - - CR45729 - CR45729 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004555 mosaic-wings mosaic wings http://flybase.org/reports/FBgn0004555 - gene - - - "mow, mosaic-wings" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" wing FBgn0002917 na narrow abdomen http://flybase.org/reports/FBgn0002917 "FBgn0004144, FBgn0030560" protein_coding_gene ion channel activity ; GO:0005216 | inferred from mutant phenotype cation channel activity ; GO:0005261 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 social behavior ; GO:0035176 | inferred from mutant phenotype membrane depolarization during action potential ; GO:0086010 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype response to anesthetic ; GO:0072347 | inferred from mutant phenotype circadian behavior ; GO:0048512 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from biological aspect of ancestor with PANTHER:PTN001295293 sensory perception of touch ; GO:0050975 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype neuronal cell body ; GO:0043025 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 axon terminus ; GO:0043679 | inferred from direct assay "har38, Dmalpha1U, CG1517, Dma1U, alpha1U, harA, har, har85, na, Na, har 38, har 85, NA, NALCN" "IPR005821:Ion transport domain, IPR028823:Sodium leak channel non-selective protein" CG1517 11-Aug-17 DroID_v2017_08 "Drer\scn4aa, Drer\cacna1fa, Drer\cacna1c, Drer\scn1a, Drer\cacna1sa, Drer\scn8ab, Drer\cacna1sb, Drer\scn4ab, Drer\cacna1ba, Drer\cacna1aa, Drer\cacna1da, Drer\scn1lab, Drer\nalcn, Drer\cacna1ab, Drer\cacna1e, Drer\cacna1fb, Drer\cacna1eb, Drer\cacna1bb" Scer\CCH1 "Cele\F17C8.6, Cele\egl-19, Cele\unc-77, Cele\nca-2, Cele\unc-2" "Xtro\cacna1a, Xtro\scn4a, Xtro\scn5a, Xtro\cacna1f, Xtro\nalcn, Xtro\scn3a, Xtro\cacna1s" "Mmus\Cacna1b, Mmus\Scn5a, Mmus\Cacna1a, Mmus\Cacna1d, Mmus\Cacna1f, Mmus\Scn10a, Mmus\Scn11a, Mmus\Cacna1c, Mmus\Scn8a, Mmus\Cacna1s, Mmus\Nalcn, Mmus\Catsper1, Mmus\Catsper2, Mmus\Scn9a, Mmus\Scn3a, Mmus\Cacna1e" "Hsap\CACNA1S, Hsap\SCN9A, Hsap\NALCN, Hsap\SCN3A, Hsap\CACNA1B, Hsap\SCN11A, Hsap\CATSPER1, Hsap\CACNA1A, Hsap\CACNA1D, Hsap\SCN8A, Hsap\CACNA1C, Hsap\SCN10A, Hsap\CACNA1F, Hsap\SCN5A" adult stage " supraesophageal ganglion

subset , optic lobe

subset , ellipsoid body

subset " "viable,fertile,chemical sensitive,locomotor behavior defective,locomotor rhythm defective,circadian behavior defective,wild-type,chemical resistant,recessive,gravitaxis defective,visible,behavior defective,lethal,partially,partially lethal - majority die,some die during pupal stage,flight defective,neuroanatomy defective,touch sensitivity defective" "adult abdomen,adult head,wing,thorax,mesothoracic tergum,ganglion mother cell,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0004438 prd1 paired-like 1 http://flybase.org/reports/FBgn0004438 - gene - - - prd1 - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | <8-12 hr , oogenesis stage " FBgn0259945 Ttd11 TRPL translocation defect 11 http://flybase.org/reports/FBgn0259945 protein_coding_gene - - - Ttd11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019759 l(1)75B1 lethal (1) 75B1 http://flybase.org/reports/FBgn0019759 - gene - - - l(1)75B1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263741 CG43666 - http://flybase.org/reports/FBgn0263741 protein_coding_gene - - - "CG43666, CG15226" - CG43666 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pharate adult stage" trichogen cell FBgn0039889 Arl4 ADP ribosylation factor-like 4 http://flybase.org/reports/FBgn0039889 protein_coding_gene GTP binding ; GO:0005525 | inferred from sequence or structural similarity with HGNC:695 small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 biological_process ; GO:0008150 | no biological data available intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR024156 cleavage furrow ; GO:0032154 | inferred from direct assay "BcDNA:AT26185, CG2219, CG 2219, ARL4B, Q9V4B2, Arl4, arl4" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024156:Small GTPase superfamily, ARF type" CG2219 11-Aug-17 DroID_v2017_08 "Drer\arf5, Drer\zgc:77650, Drer\trim23, Drer\arl5a, Drer\arl14, Drer\arl4ca, Drer\arl8, Drer\zgc:110286, Drer\arl4ab, Drer\arl11, Drer\arf1, Drer\arl9, Drer\arf4a, Drer\arl4cb, Drer\arl5c, Drer\si:ch1073-165f9.2, Drer\arf2a, Drer\arl6, Drer\arl4aa, Drer\arf3a, Drer\arf3b, Drer\arl4d" "Scer\ARF2, Scer\ARF3, Scer\ARF1" "Cele\C56E6.2, Cele\arf-1.1" "Xtro\arl11, Xtro\arl4c, Xtro\arl11, Xtro\arf5, Xtro\arl9, Xtro\arl5b, Xtro\arl6, Xtro\arf1, Xtro\arf4, Xtro\arl14, Xtro\trim23, Xtro\arl5a, Xtro\arf3, Xtro\arl5c, Xtro\arl4a" "Mmus\Arl4c, Mmus\Arl4a, Mmus\Arl9, Mmus\Arf1, Mmus\Arf2, Mmus\Arl5b, Mmus\Arl11, Mmus\Arf4, Mmus\Arf5, Mmus\Arl4d, Mmus\Arl5c, Mmus\Arl6, Mmus\Arl5a, Mmus\Arf3, Mmus\Trim23" "Hsap\ARL6, Hsap\ARL14, Hsap\ARL17B, Hsap\ARF3, Hsap\ARF5, Hsap\ARL5C, Hsap\ARL4A, Hsap\ARF4, Hsap\TRIM23, Hsap\ARL4D, Hsap\ARL4C, Hsap\ARF1, Hsap\ARL5B, Hsap\ARL5A, Hsap\ARL9, Hsap\ARL11" viable FBgn0264675 CR43960 - http://flybase.org/reports/FBgn0264675 non_protein_coding_gene - - - CR43960 - CR43960 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069238 gl(1)170-20 gl(1)170-20 http://flybase.org/reports/FBgn0069238 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(1)170-20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,terminal phenotype,germline clone,maternal effect" "filzkorper,germline clone,maternal effect,embryo" FBgn0082637 S(CycE[JP])13S1 S(CycE[JP])13S1 http://flybase.org/reports/FBgn0082637 gene - - - "13S1, S(CycE[JP])13S1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030090 fend forked end http://flybase.org/reports/FBgn0030090 protein_coding_gene - motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype - "fend, CG12664, LD14, BcDNA:RH56795, ld14, Dromel_CG12664_FBtr0071349_ld14_mORF" - CG12664 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,viable,fertile,visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive" "motor neuron | third instar larval stage,intersegmental nerve | third instar larval stage,embryonic/larval neuromuscular junction,ectopic,intersegmental nerve,mesothoracic tergum" FBgn0043866 palido palido http://flybase.org/reports/FBgn0043866 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available palido - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026341 Su(tor)2-164-14 Su(tor)2-164-14 http://flybase.org/reports/FBgn0026341 - gene - - - Su(tor)2-164-14 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033916 Usp20-33 Ubiquitin specific protease 20/33 http://flybase.org/reports/FBgn0033916 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:20059 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:20059 protein deubiquitination ; GO:0016579 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG8494, Usp20-33, Usp33, Usp20, USP20, Q7JW61, usp20-33" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR006615:Peptidase C19, ubiquitin-specific peptidase, DUSP domain, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG8494 11-Aug-17 DroID_v2017_08 "Drer\usp20, Drer\usp31, Drer\usp32, Drer\usp19, Drer\usp33, Drer\usp11, Drer\usp43a, Drer\usp4, Drer\usp43b, Drer\usp1" "Scer\UBP5, Scer\UBP10, Scer\DOA4, Scer\UBP12" - "Xtro\usp4, Xtro\usp33, Xtro\usp19, Xtro\usp31, Xtro\usp20, Xtro\usp32, Xtro\usp15" "Mmus\Usp11, Mmus\Usp32, Mmus\Usp19, Mmus\Usp33, Mmus\Usp20, Mmus\Usp43, Mmus\Usp15, Mmus\Usp31, Mmus\Usp4, Mmus\Usp1" "Hsap\USP31, Hsap\USP33, Hsap\USP1, Hsap\USP15, Hsap\USP6, Hsap\USP19, Hsap\USP11, Hsap\USP4, Hsap\USP20, Hsap\USP32, Hsap\USP43" "viable,short lived,locomotor behavior defective" FBgn0015961 l(2)46Co lethal (2) 46Co http://flybase.org/reports/FBgn0015961 - gene - - - "group 3, l(2)46Co" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029976 snz snazarus http://flybase.org/reports/FBgn0029976 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 phospholipid binding ; GO:0005543 | inferred from sequence model determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from sequence model "snz, CG1514, DmSNX25, Snz" "IPR001683:Phox homologous domain, IPR003114:Phox-associated domain, IPR013937:Sorting nexin, C-terminal, IPR016137:RGS domain" CG1514 11-Aug-17 DroID_v2017_08 "Drer\snx27b, Drer\snx13, Drer\kif16ba, Drer\snx27a, Drer\snx14, Drer\snx25" Scer\MDM1 "Cele\snx-27, Cele\snx-14, Cele\snx-13" "Xtro\snx25, Xtro\kif16b" "Mmus\Snx13, Mmus\Snx29, Mmus\Snx14, Mmus\Sgk3, Mmus\Snx25, Mmus\Rps6kc1, Mmus\Kif16b, Mmus\Snx20, Mmus\Snx15, Mmus\Snx27" "Hsap\SNX25, Hsap\SNX27, Hsap\SNX13, Hsap\SGK3, Hsap\RPS6KC1, Hsap\SNX15, Hsap\SNX14" "long lived,recessive,fertile,female fertile,viable,maternal effect" FBgn0060585 l(3)S094105b lethal (3) S094105b http://flybase.org/reports/FBgn0060585 gene - - - "0941/05, l(3)S094105b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015429 l(1)2BCa lethal (1) 2BCa http://flybase.org/reports/FBgn0015429 - gene - - - l(1)2BCa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0038509 CG14332 - http://flybase.org/reports/FBgn0038509 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14332 - CG14332 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034902 CG5532 - http://flybase.org/reports/FBgn0034902 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005349 CG5532 IPR005349:TMEM14 family CG5532 11-Aug-17 DroID_v2017_08 "Drer\zgc:163080, Drer\tmem14cb, Drer\tmem14ca" Scer\YJR085C - "Xtro\tmem14a, Xtro\tmem14c" "Mmus\Tmem14a, Mmus\Tmem14c" "Hsap\TMEM14C, Hsap\TMEM14B, Hsap\TMEM14A" viable FBgn0030502 tth toothrin http://flybase.org/reports/FBgn0030502 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype - "anon-EST:fe2G7, CG12175, tth" IPR025750:Requiem/DPF N-terminal domain CG12175 11-Aug-17 DroID_v2017_08 "Drer\phf10, Drer\dpf3, Drer\dpf2l, Drer\dpf2, Drer\dpf1" "Scer\SFP1, Scer\SAS3" "Cele\dpff-1, Cele\phf-10, Cele\mys-4" "Xtro\dpf2, Xtro\phf10, Xtro\dpf3" "Mmus\Dpf3, Mmus\Phf10, Mmus\Dpf2, Mmus\Dpf1" "Hsap\DPF1, Hsap\PHF10, Hsap\DPF3, Hsap\DPF2" "viable,body color defective,visible,partially lethal - majority die,some die during pupal stage" "mesothoracic tergum,trichogen cell" FBgn0050417 tbrd-3 testis-specifically expressed bromodomain containing protein-3 http://flybase.org/reports/FBgn0050417 protein_coding_gene - - chromosome ; GO:0005694 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "CG17692, CG30417, tbrd-3, tBRD-3" "IPR001487:Bromodomain, IPR027353:NET domain" CG30417 11-Aug-17 DroID_v2017_08 "Drer\brd4, Drer\brd3a, Drer\brd2a, Drer\brd3b, Drer\brdt" "Scer\BDF1, Scer\BDF2" "Cele\bet-1, Cele\F13C5.2, Cele\F59F5.7, Cele\bet-2" "Xtro\brd4, Xtro\brdt, Xtro\brd2, Xtro\brd3" "Mmus\Brd2, Mmus\Brdt, Mmus\Brd4, Mmus\Brd3" "Hsap\BRD4, Hsap\CCDC127, Hsap\BRD3, Hsap\BRDT, Hsap\BRD2" "viable,visible" trichogen cell FBgn0037686 RpL34b Ribosomal protein L34b http://flybase.org/reports/FBgn0037686 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000844532 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR008195 ribosome biogenesis ; GO:0042254 | inferred from biological aspect of ancestor with PANTHER:PTN000844532 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay "anon-EST:fe1E8, anon-EST:fe1C10, CG9354, RpL34b, RpL34, L34b, Rp L34b" "IPR018065:Ribosomal protein L34e, conserved site, IPR008195:Ribosomal protein L34Ae" CG9354 11-Aug-17 DroID_v2017_08 Drer\rpl34 "Scer\RPL34B, Scer\RPL34A" Cele\rpl-34 Xtro\rpl34 "Mmus\Rpl34, Mmus\Gm4705, Mmus\Rpl34-ps1" Hsap\RPL34 viable DRSC16475 IK -1.761711107 -0.148091675 0.095935249 -0.014494017 -1.8112065 -0.499384114 FBgn0014888 Su(phl)7 Suppressor of pole hole 7 http://flybase.org/reports/FBgn0014888 - gene - - - "Su(D-raf)7, Su(phl)7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000759 fs(1)A473 female sterile (1) A473 http://flybase.org/reports/FBgn0000759 - gene - - - "fs(1)473, fs(1)A473" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile soma-dependent,recessive" egg FBgn0039872 salt salty dog http://flybase.org/reports/FBgn0039872 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 basolateral plasma membrane ; GO:0016323 | inferred from direct assay "CG2196, salt, dSLC5A7" IPR001734:Sodium/solute symporter CG2196 11-Aug-17 DroID_v2017_08 "Drer\slc5a3a, Drer\slc5a8l, Drer\slc5a6b, Drer\slc5a9, Drer\slc5a2, Drer\slc5a5, Drer\slc5a1, Drer\slc5a6a, Drer\slc5a11, Drer\slc5a12, Drer\slc5a8, Drer\si:dkeyp-9d4.5, Drer\LOC568338" Scer\DUR3 "Cele\ZK822.5, Cele\F52H2.4" "Xtro\slc5a2, Xtro\slc5a9, Xtro\slc5a11, Xtro\slc5a5, Xtro\slc5a1.1, Xtro\slc5a8, Xtro\slc5a12" "Mmus\Slc5a4a, Mmus\Slc5a8, Mmus\Gm5134, Mmus\Slc5a9, Mmus\Slc5a12, Mmus\Slc5a4b, Mmus\Slc5a10, Mmus\Slc5a3, Mmus\Slc5a5, Mmus\Slc5a11, Mmus\Slc5a2, Mmus\Slc5a6, Mmus\Slc5a1" "Hsap\SLC5A8, Hsap\SLC5A6, Hsap\SLC5A2, Hsap\SLC5A1, Hsap\SLC5A12, Hsap\SLC5A11, Hsap\SLC5A9, Hsap\SLC5A5, Hsap\SLC5A4, Hsap\SLC5A10, Hsap\SLC5A3" "stress response defective,viable" FBgn0267923 CR46204 - http://flybase.org/reports/FBgn0267923 non_protein_coding_gene - - - "CR46204, lincRNA.172" - CR46204 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044128 E(rst)A5 E(rst)A5 http://flybase.org/reports/FBgn0044128 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "A5, E(rst)A5" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0263665 CR43656 - http://flybase.org/reports/FBgn0263665 non_protein_coding_gene - - - CR43656 - CR43656 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060510 l(3)S104210a lethal (3) S104210a http://flybase.org/reports/FBgn0060510 gene - - - "1042/10, l(3)S104210a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0020894 Su(osk)H1 Suppressor of oskar H1 http://flybase.org/reports/FBgn0020894 - gene - - - "H1, Su(osk)H1" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266981 CR45432 - http://flybase.org/reports/FBgn0266981 non_protein_coding_gene - - - CR45432 - CR45432 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050430 CG30430 - http://flybase.org/reports/FBgn0050430 protein_coding_gene - - - "NEST:bs13e09, NEST:bs27g03, NEST:bs29b02, NEST:bs15d07, NEST:bs04a11, NEST:bs02g04, NEST:bs01g11, NEST:bs12g08, NEST:bs14e02, NEST:bs15a10, NEST:bs17g03, CG30430" - CG30430 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0014951 bwl bow-legged http://flybase.org/reports/FBgn0014951 - gene - - - bwl - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,viable,poor" "wing,femur,tibia,macrochaeta,leg" FBgn0266725 CR45198 - http://flybase.org/reports/FBgn0266725 non_protein_coding_gene - - - CR45198 - CR45198 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000794 fs(1)de5 female sterile (1) defective eggs 5 http://flybase.org/reports/FBgn0000794 - gene - - - "de5, fs(1)de5" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "endochorion,dorsal appendage,chorion" FBgn0267877 CR46165 - http://flybase.org/reports/FBgn0267877 pseudogene_attribute - - - "CR46165, CG12717-related" - CR46165 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040120 l(2)23Dd lethal (2) 23Dd http://flybase.org/reports/FBgn0040120 gene - - - "l(2)23Cb, l(2)23Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065150 l(3)SH070 lethal (3) SH070 http://flybase.org/reports/FBgn0065150 gene - - - "l(3)SH070, l(2)SH3 070" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0261737 EC3959 - http://flybase.org/reports/FBgn0261737 gene - - - EC3959 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0031966 CG14532 - http://flybase.org/reports/FBgn0031966 protein_coding_gene - - - CG14532 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065122 l(3)SH145 lethal (3) SH145 http://flybase.org/reports/FBgn0065122 gene - - - "l(3)SH145, l(2)SH3 145" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058279 CG40279 - http://flybase.org/reports/FBgn0058279 protein_coding_gene - - - CG40279 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266487 CG45086 - http://flybase.org/reports/FBgn0266487 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45086, Dromel_CG17759_galpha49b_uORF" - CG45086 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043580 MESK3 Misexpression Suppressor of KDN 3 http://flybase.org/reports/FBgn0043580 gene - positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with ksr inferred from genetic interaction with Ras85D - MESK3 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036787 CG4306 - http://flybase.org/reports/FBgn0036787 protein_coding_gene gamma-glutamylcyclotransferase activity ; GO:0003839 | inferred from electronic annotation with InterPro:IPR017939 hemolymph coagulation ; GO:0042381 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay CG4306 "IPR017939:Gamma-glutamylcyclotransferase, IPR013024:Gamma-glutamyl cyclotransferase-like" CG4306 11-Aug-17 DroID_v2017_08 "Drer\ggctb, Drer\ggcta" - Cele\C44B7.7 Xtro\ggct Mmus\Ggct Hsap\GGCT FBgn0032876 Cen Centrocortin http://flybase.org/reports/FBgn0032876 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with cnn embryonic cleavage ; GO:0040016 | inferred from mutant phenotype cleavage furrow ; GO:0032154 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "38E.1, CG1962, Cen, cen" IPR026079:Cerebellar degeneration-related protein 2 CG1962 11-Aug-17 DroID_v2017_08 "Drer\cdr2a, Drer\cdr2l, Drer\si:ch1073-272o11.3" - - "Xtro\cdr2l, Xtro\cdr2" "Mmus\Cdr2, Mmus\Cdr2l" "Hsap\CDR2, Hsap\CDR2L, Hsap\LOC101060399" "viable,fertile,partially lethal - majority die,maternal effect" "cleavage furrow | embryonic stage | maternal effectFs(2)Ket-RX32),spindle | embryonic stage | maternal effectFs(2)Ket-RX32),cleavage furrow | embryonic stagenos.UTR.THsimVP16" FBgn0000550 Edg64CD Ecdysone-dependent gene 64CD http://flybase.org/reports/FBgn0000550 - gene - - - "Edg64, Edg64CD" - - 11-Aug-17 DroID_v2017_08 - - - - - - prepupal stage epidermis

FBgn0052843 Dh31-R Diuretic hormone 31 Receptor http://flybase.org/reports/FBgn0052843 protein_coding_gene calcitonin receptor activity ; GO:0004948 | inferred from electronic annotation with InterPro:IPR003287 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model diuretic hormone receptor activity ; GO:0008036 | inferred from physical interaction with Dh31 calcitonin receptor activity ; GO:0004948 | inferred from sequence or structural similarity cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG17415, CG17043, anon-WO0170980.137, anon-WO0170980.136, CG32843, DmeCG32843, DH31-R1, DH31R, DH31-R, DH31, Dh31-R, Dh31-R1, dh31-R1" "IPR000832:GPCR, family 2, secretin-like, IPR001879:GPCR, family 2, extracellular hormone receptor domain, IPR003287:GPCR, family 2, calcitonin receptor family, IPR017981:GPCR, family 2-like, IPR017983:GPCR, family 2, secretin-like, conserved site" CG32843 11-Aug-17 DroID_v2017_08 "Drer\calcrla, Drer\vipr1b, Drer\pth1rb, Drer\gipr, Drer\ghrhr2, Drer\calcrlb, Drer\gcgrb, Drer\pth2r, Drer\vipr2, Drer\calcr, Drer\adcyap1r1b, Drer\adcyap1r1a, Drer\crhr2, Drer\si:dkeyp-4h4.1, Drer\ghrhra, Drer\calcrl2, Drer\ghrhrb, Drer\crhr1, Drer\gcgra, Drer\vipr1a, Drer\pth1ra" - "Cele\seb-2, Cele\seb-3, Cele\pdfr-1" "Xtro\calcrl, Xtro\crhr1.1, Xtro\gipr, Xtro\adcyap1r1, Xtro\pth1r, Xtro\crhr1.2, Xtro\vipr1, Xtro\gcgr, Xtro\pth2r" "Mmus\Pth2r, Mmus\Calcr, Mmus\Crhr2, Mmus\Sctr, Mmus\Gipr, Mmus\Ghrhr, Mmus\Glp1r, Mmus\Crhr1, Mmus\Adcyap1r1, Mmus\Calcrl, Mmus\Glp2r, Mmus\Vipr1, Mmus\Pth1r, Mmus\Gcgr, Mmus\Vipr2" "Hsap\CRHR2, Hsap\ADCYAP1R1, Hsap\GIPR, Hsap\GCGR, Hsap\GLP1R, Hsap\VIPR2, Hsap\CALCR, Hsap\GHRHR, Hsap\CALCRL, Hsap\VIPR1, Hsap\GLP2R, Hsap\PTH1R, Hsap\SCTR, Hsap\PTH2R, Hsap\CRHR1-IT1-CRHR1, Hsap\CRHR1" "viable,fertile" FBgn0266804 CR45266 - http://flybase.org/reports/FBgn0266804 non_protein_coding_gene - - - CR45266 - CR45266 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011984 tRNA:Ser-AGA-2-4 transfer RNA:Serine-AGA 2-4 http://flybase.org/reports/FBgn0011984 "FBgn0003831, FBgn0011968, FBgn0011979, FBgn0051951, FBgn0060065" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "tRNA ser7, 777-3, Ser-tRNA-7, tRNA-Ser7, tRNA[Ser][[7]], tRNA[[7]][Ser], tRNA[Ser], AE002638.trna2-SerAGA, tRNA:S:AGA:AE002638-a, CR31951, tRNA:ser, tRNA:S, tRNA:S7, tRNA:ser7, tRNA:ser7:23Ea, tRNA[[Ser]], chr2L.trna35-SerAGA, tRNA-Ser-AGA-2-4, tRNA:Ser-AGA-2-4, tRNA:S7:23Ea, UCU" - CR31951 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002193 l(3)63Bd lethal (3) 63Bd http://flybase.org/reports/FBgn0002193 - gene - - - l(3)63Bd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044113 E(rst)C210 E(rst)C210 http://flybase.org/reports/FBgn0044113 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C210, E(rst)C210" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266647 CG45154 - http://flybase.org/reports/FBgn0266647 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR45154, CG45154" - CG45154 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262869 Gfrl Glial cell line-derived neurotrophic family receptor-like http://flybase.org/reports/FBgn0262869 protein_coding_gene cell adhesion molecule binding ; GO:0050839 | inferred from physical interaction with Fas2 - anchored component of external side of plasma membrane ; GO:0031362 | inferred from direct assay "mun, CG43224, CG42801, CG17205, BcDNA:GH26447, CG34118, CG17208, CG42625, CG34119, CG4342, CG33518, CG42401, CG17204, CG17203, Gfrl, DmGfrl" IPR016017:GDNF/GAS1 CG43224 11-Aug-17 DroID_v2017_08 "Drer\gfra4a, Drer\gfra1b, Drer\graf4b, Drer\gfra2b, Drer\gfra3, Drer\gfra1a, Drer\gfra2a" - "Cele\Y53G8AM.6, Cele\H34I24.1, Cele\Y69A2AR.31, Cele\Y53G8AR.1, Cele\Y43F8C.5" Xtro\gfra3 "Mmus\Gfra3, Mmus\Gfra4, Mmus\Gfra2, Mmus\Gfral, Mmus\Gfra1" "Hsap\GFRA3, Hsap\GFRAL, Hsap\GFRA1, Hsap\GFRA2, Hsap\GFRA4" FBgn0263563 mir-4956 mir-4956 stem loop http://flybase.org/reports/FBgn0263563 miRNA_gene - - - "mir-4956, dme-mir-4956, CR43548" - CR43548 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031858 CG17378 - http://flybase.org/reports/FBgn0031858 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17378 IPR022096:SBF1/SBF2 domain CG17378 11-Aug-17 DroID_v2017_08 Drer\zgc:91860 - - Xtro\kiaa0513 Mmus\6430548M08Rik Hsap\KIAA0513 "lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0001792 l(1)Mb22 lethal (1) Mb22 http://flybase.org/reports/FBgn0001792 - gene - - - l(1)Mb22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031195 CG17600 - http://flybase.org/reports/FBgn0031195 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007237 "CG17602, CG17600" "IPR030417:Membrane-spanning 4-domains subfamily A, IPR007237:CD20-like family" CG17600 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-291c23.2, Drer\si:ch73-56d11.3, Drer\tmem176l.3b, Drer\ms4a17a.11, Drer\LOC103911081, Drer\ms4a17a.6, Drer\ms4a17a.9, Drer\ms4a17a.5, Drer\LOC798290, Drer\si:dkey-77f5.10, Drer\ms4a17a.12, Drer\si:dkey-7j14.6, Drer\ms4a17c.1, Drer\ms4a17a.8, Drer\tmem176l.3a, Drer\ms4a17a.3, Drer\si:dkey-7j14.5, Drer\ms4a17c.2, Drer\si:dkey-30c15.13, Drer\tmem176l.1, Drer\ms4a17a.16, Drer\tmem176, Drer\ms4a17a.10, Drer\tmem176l.4, Drer\ms4a17a.4, Drer\ms4a17a.7, Drer\ms4a17a.1, Drer\ms4a17a.17, Drer\si:ch211-135n15.2" - - - "Mmus\Ms4a2, Mmus\Ms4a6b, Mmus\Ms4a4b, Mmus\Ms4a6d, Mmus\Gm8369, Mmus\1700017D01Rik, Mmus\Ms4a4d, Mmus\Ms4a3, Mmus\Ms4a6c, Mmus\Ms4a10, Mmus\Ms4a15, Mmus\Ms4a13, Mmus\Ms4a4c, Mmus\Ms4a5, Mmus\Ms4a12, Mmus\Ms4a4a, Mmus\Ms4a14, Mmus\Ms4a7, Mmus\Ms4a1, Mmus\Ms4a8a, Mmus\Tmem212, Mmus\Ms4a18" "Hsap\MS4A14, Hsap\MS4A3, Hsap\MS4A1, Hsap\MS4A6A, Hsap\MS4A5, Hsap\TMEM212, Hsap\MS4A7, Hsap\MS4A4E, Hsap\MS4A2, Hsap\MS4A4A, Hsap\MS4A18, Hsap\MS4A8, Hsap\MS4A15, Hsap\MS4A10, Hsap\MS4A13, Hsap\MS4A6E, Hsap\MS4A12" "viable,fertile" DRSC22753 I 1.741452663 -0.072786419 0.335203846 0.048923869 -0.906583808 0.016171867 FBgn0005733 l(1)TK218 lethal (1) TK218 http://flybase.org/reports/FBgn0005733 - gene - - - "l218, l(1)TK218" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "eye,lamina" FBgn0065625 l(2)SH0795 lethal (2) SH0795 http://flybase.org/reports/FBgn0065625 gene - - - "l(2)SH0795, l(2)SH2 0795" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005728 l(1)TK203 lethal (1) TK203 http://flybase.org/reports/FBgn0005728 - gene - - - "l203, l(1)TK203" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0039308 CG11889 - http://flybase.org/reports/FBgn0039308 protein_coding_gene - - - "CG33091, CG11889" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG11889 11-Aug-17 DroID_v2017_08 - - "Cele\F56A4.5, Cele\C29F7.2, Cele\E02C12.10, Cele\Y45G12C.4, Cele\H37A05.2, Cele\dhs-27, Cele\F58B4.5, Cele\nhr-246, Cele\E02C12.9, Cele\E02C12.8, Cele\C29F7.1, Cele\C18B10.6, Cele\E02C12.6, Cele\H06H21.8" - - - DRSC14426 I 1.858612401 0.064515664 0.518968489 0.345428587 0.126351437 0.223857066 FBgn0002163 l(2)Sp7 lethal (2) Sp7 http://flybase.org/reports/FBgn0002163 - gene - - - l(2)Sp7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013558 l(3)2 lethal (3) 2 http://flybase.org/reports/FBgn0013558 - gene - - - l(3)2 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015924 crq croquemort http://flybase.org/reports/FBgn0015924 "FBgn0011572, FBgn0044547, FBgn0051655" protein_coding_gene scavenger receptor activity ; GO:0005044 | inferred from sequence or structural similarity with emp scavenger receptor activity ; GO:0005044 | traceable author statement "apoptotic process ; GO:0006915 | traceable author statement macrophage activation ; GO:0042116 | traceable author statement phagocytosis, engulfment ; GO:0006911 | traceable author statement phagocytosis ; GO:0006909 | traceable author statement phagosome maturation ; GO:0090382 | inferred from mutant phenotype immune response-regulating cell surface receptor signaling pathway involved in phagocytosis ; GO:0002433 | inferred from direct assay regulation of phagocytosis, engulfment ; GO:0060099 | NOT inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern regulation of phagocytosis ; GO:0050764 | traceable author statement apoptotic process ; GO:0006915 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | traceable author statement" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "CG4280, Cd36, cqm, D-CD36, CG31655, anon-WO0140519.8, crq, Crq, cqr, CRQ, Cqr, CD36" IPR002159:CD36 family CG4280 11-Aug-17 DroID_v2017_08 "Drer\LOC564077, Drer\scarb1, Drer\cd36, Drer\scarb2" - "Cele\scav-4, Cele\scav-6, Cele\scav-1, Cele\scav-2, Cele\scav-3, Cele\scav-5" "Xtro\scarb2, Xtro\cd36, Xtro\scarb1" "Mmus\Scarb2, Mmus\Cd36, Mmus\Scarb1" "Hsap\SCARB1, Hsap\SCARB2, Hsap\CD36" " larval stage , embryonic stage | stage >=11 " " embryonic/larval hemocyte

, hemocyte

" "neuroanatomy defective,conditional,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal multidendritic neuron ddaC | pupal stage,dorsal multidendritic neuron ddaC,conditional,phagolysosomeal),presumptive embryonic/larval central nervous system,embryonic/larval glial cell" FBgn0267188 CR45628 - http://flybase.org/reports/FBgn0267188 non_protein_coding_gene - - - CR45628 - CR45628 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028864 CG18477 - http://flybase.org/reports/FBgn0028864 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "SPH69, BG:DS07108.1, CG18477" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG18477 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Klk1b21, Mmus\Klk1b4, Mmus\F11, Mmus\Klk1b16, Mmus\Klk1b27, Mmus\Egfbp2, Mmus\Klk1, Mmus\Klk1b9, Mmus\Klk1b11, Mmus\Klk1b22, Mmus\Klk1b5, Mmus\Klk1b3, Mmus\Klk1b24, Mmus\Klk11, Mmus\Klk1b26, Mmus\Klk1b8, Mmus\Klkb1, Mmus\Klk1b1" "Hsap\F11, Hsap\KLK2, Hsap\KLK1, Hsap\KLKB1, Hsap\KLK3, Hsap\KLK11" FBgn0036010 Ir67a Ionotropic receptor 67a http://flybase.org/reports/FBgn0036010 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model AMPA glutamate receptor activity ; GO:0004971 | inferred from biological aspect of ancestor with PANTHER:PTN000438080 detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a AMPA glutamate receptor complex ; GO:0032281 | inferred from biological aspect of ancestor with PANTHER:PTN000438080 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir67a, DmelIR67a, CG12525, IR67a" - CG12525 11-Aug-17 DroID_v2017_08 "Drer\gria2b, Drer\gria4a, Drer\gria4b, Drer\gria2a, Drer\gria3a, Drer\gria3b" - - - "Mmus\Gria4, Mmus\Gria2, Mmus\Gria3, Mmus\Gria1" "Hsap\GRIA4, Hsap\GRIA3, Hsap\GRIA2, Hsap\GRIA1" viable FBgn0033352 PAN2 Poly(A)-binding protein-dependent poly(A) ribonuclease 2 http://flybase.org/reports/FBgn0033352 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 poly(A)-specific ribonuclease activity ; GO:0004535 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000404664 poly(A)-specific ribonuclease activity ; GO:0004535 | contributes_to inferred from sequence or structural similarity with SGD:S000003062 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR030843 nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from genetic interaction with Pop2 nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from sequence or structural similarity with SGD:S000003062 PAN complex ; GO:0031251 | inferred from biological aspect of ancestor with PANTHER:PTN000404664 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000404664 PAN complex ; GO:0031251 | inferred from sequence or structural similarity with SGD:S000003062 "PAN2, Pan2, CG8232, pan2, A1Z7K9" "IPR017986:WD40-repeat-containing domain, IPR012337:Ribonuclease H-like domain, IPR013520:Exonuclease, RNase T/DNA polymerase III, IPR015943:WD40/YVTN repeat-like-containing domain, IPR030843:PAB-dependent poly(A)-specific ribonuclease subunit PAN2, IPR028881:PAN2 domain, IPR028889:Ubiquitin specific protease domain" CG8232 11-Aug-17 DroID_v2017_08 Drer\pan2 Scer\PAN2 "Cele\sel-10, Cele\panl-2" Xtro\pan2 Mmus\Pan2 Hsap\PAN2 "viable,fertile" FBgn0064140 sl(2)AM1 sl(2)AM1 http://flybase.org/reports/FBgn0064140 gene - - - sl(2)AM1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0026206 mei-P26 meiotic P26 http://flybase.org/reports/FBgn0026206 FBgn0027551 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1860040" meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype gamete generation ; GO:0007276 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from genetic interaction with bam protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:1860040 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:1860040 "BcDNA:GH10646, CG12218, AF145661, mei-P26, Mei-P26, MEI-P26, mei-p26" "IPR000315:B-box-type zinc finger, IPR001841:Zinc finger, RING-type, IPR003649:B-box, C-terminal, IPR013017:NHL repeat, subgroup, IPR011042:Six-bladed beta-propeller, TolB-like, IPR017907:Zinc finger, RING-type, conserved site, IPR011989:Armadillo-like helical, IPR001258:NHL repeat, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG12218 11-Aug-17 DroID_v2017_08 "Drer\trim24, Drer\trim66, Drer\trim35-1, Drer\trim3b, Drer\trim3a, Drer\trim25l, Drer\trim2a, Drer\trim2b, Drer\trim33l, Drer\trim32" - "Cele\nhl-2, Cele\madd-2" "Xtro\trim3, Xtro\trim32, Xtro\trim2" "Mmus\Nhlrc4, Mmus\Trim66, Mmus\Trim32, Mmus\Trim56, Mmus\Trim2, Mmus\Trim3" "Hsap\TRIM56, Hsap\TRIM66, Hsap\TRIM2, Hsap\NHLRC4, Hsap\TRIM32, Hsap\TRIM3" "female sterile,recessive,neurophysiology defective,male fertile,meiotic cell cycle defective,semidominant,female fertile,reduced,wild-type,viable,sterile,male sterile,lethal" "egg chamber,nurse cell,egg,ovary,nucleolus & ovary,testis,ventral nerve cord,presumptive embryonic/larval peripheral nervous system,spermatozoon,spermatid,oocyte,male germline cyst,nucleolus,spermatocyte cyst" FBgn0035742 CG8629 - http://flybase.org/reports/FBgn0035742 protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 - - "BcDNA:RE33457, CG8629" "IPR000582:Acyl-CoA-binding protein, ACBP, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle" CG8629 11-Aug-17 DroID_v2017_08 "Drer\acbd5b, Drer\acbd4, Drer\mettl23, Drer\acbd6, Drer\acbd7, Drer\LOC103909942, Drer\dbi, Drer\zgc:92030" Scer\ACB1 "Cele\acbp-6, Cele\acbp-1, Cele\acbp-5, Cele\acbp-3, Cele\maa-1, Cele\acbp-4" "Xtro\mettl23, Xtro\acbd7, Xtro\acbd6, Xtro\acbd5, Xtro\eci2" "Mmus\Dbi, Mmus\Mettl23, Mmus\Dbil5, Mmus\Acbd6, Mmus\Acbd5, Mmus\Acbd4, Mmus\Acbd7, Mmus\Eci2" "Hsap\ACBD7, Hsap\ACBD5, Hsap\ACBD6, Hsap\DBI, Hsap\ACBD4, Hsap\METTL23, Hsap\ECI2" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0266673 Sec10 Secretory 10 http://flybase.org/reports/FBgn0266673 protein_coding_gene beta-catenin binding ; GO:0008013 | inferred from physical interaction with arm vesicle docking ; GO:0048278 | inferred from electronic annotation with InterPro:IPR009976 exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000250585 synaptic vesicle docking ; GO:0016081 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity Golgi to plasma membrane transport ; GO:0006893 | inferred from biological aspect of ancestor with PANTHER:PTN000250585 vesicle tethering involved in exocytosis ; GO:0090522 | inferred by curator from GO:0000145 neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle targeting ; GO:0016080 | non-traceable author statement exocyst ; GO:0000145 | non-traceable author statement exocyst ; GO:0000145 | inferred from direct assay exocyst ; GO:0000145 | inferred from sequence or structural similarity exocyst ; GO:0000145 | inferred from biological aspect of ancestor with PANTHER:PTN000250585 "P71, sec10, Sec10, CG6159, Sec10p, dsec10, dSec10" "IPR033960:Exocyst complex component EXOC5/Sec10, IPR009976:Exocyst complex component Sec10-like" CG6159 11-Aug-17 DroID_v2017_08 Drer\exoc5 "Scer\RCY1, Scer\SEC10" Cele\sec-10 Xtro\exoc5 Mmus\Exoc5 Hsap\EXOC5 FBgn0002100 l(2)57Da lethal (2) 57Da http://flybase.org/reports/FBgn0002100 - gene - - - "l(2)57CDb, l(2)57Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000911 fs(1)M121 female sterile (1) M121 http://flybase.org/reports/FBgn0000911 - gene - - - fs(1)M121 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0050075 CG30075 - http://flybase.org/reports/FBgn0050075 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30075 "IPR011990:Tetratricopeptide-like helical domain, IPR019734:Tetratricopeptide repeat" CG30075 11-Aug-17 DroID_v2017_08 "Drer\ttc9c, Drer\fkbp16, Drer\LOC103911693, Drer\fkbp4, Drer\fkbp6, Drer\fkbp5, Drer\ttc9b, Drer\fkbp8" - - "Xtro\fkbp4, Xtro\fkbp6, Xtro\fkbp8" "Mmus\Fkbp4, Mmus\Ttc9c, Mmus\Fkbp6, Mmus\Fkbp5, Mmus\Ttc9, Mmus\Fkbp8, Mmus\Ttc9b" "Hsap\FKBP5, Hsap\FKBP4, Hsap\TTC9C, Hsap\FKBP8, Hsap\TTC9B, Hsap\TTC9, Hsap\FKBP6" viable FBgn0037364 Rab23 Rab23 http://flybase.org/reports/FBgn0037364 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" morphogenesis of a polarized epithelium ; GO:0001738 | inferred from mutant phenotype Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000636003 smoothened signaling pathway ; GO:0007224 | NOT inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN000636003 autophagosome ; GO:0005776 | inferred from biological aspect of ancestor with PANTHER:PTN000636003 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 recycling endosome ; GO:0055037 | inferred from direct assay "DmRab23, CG2108, Rab23, rab23, Q9VNG6" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR034114:Ras-related protein Rab-23" CG2108 11-Aug-17 DroID_v2017_08 Drer\rab23 Scer\YPT7 Cele\ZK669.5 Xtro\rab23 Mmus\Rab23 Hsap\RAB23 "viable,visible,partially lethal - majority die,recessive,planar polarity defective" "wing hair,cell autonomous,somatic clone,wing,microchaeta,leg,tergite,sternite" FBgn0030686 mRpL3 mitochondrial ribosomal protein L3 http://flybase.org/reports/FBgn0030686 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P09001 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049633 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049633 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P09001 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P09001 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049633 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CG8288, L3, mRpL3" "IPR000597:Ribosomal protein L3, IPR009000:Translation protein, beta-barrel domain, IPR019927:Ribosomal protein L3, bacterial/organelle-type" CG8288 11-Aug-17 DroID_v2017_08 Drer\mrpl3 Scer\MRPL9 Cele\mrps-18C Xtro\mrpl3 Mmus\Mrpl3 Hsap\MRPL3 "viable,fertile,visible" trichogen cell FBgn0261976 Psf2 Psf2 http://flybase.org/reports/FBgn0261976 protein_coding_gene 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay "double-strand break repair via break-induced replication ; GO:0000727 | inferred from biological aspect of ancestor with PANTHER:PTN000299327 regulation of DNA-templated transcription, elongation ; GO:0032784 | inferred from sequence or structural similarity with UniProtKB:Q7ZT46 lateral inhibition ; GO:0046331 | inferred from mutant phenotype mitotic DNA replication initiation ; GO:1902975 | inferred from biological aspect of ancestor with PANTHER:PTN000299327 DNA strand elongation involved in DNA replication ; GO:0006271 | inferred from sequence or structural similarity with UniProtKB:Q7ZT46 positive regulation of G1/S transition of mitotic cell cycle ; GO:1900087 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" GINS complex ; GO:0000811 | inferred from direct assay replication fork protection complex ; GO:0031298 | inferred from biological aspect of ancestor with PANTHER:PTN000299327 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q7ZT46 "CG18013, Psf2, l(2)SH0805, P{lacW}l(2)SH0805[SH0805], l(2)SH2 0805" "IPR007257:DNA replication complex GINS protein Psf2, IPR021151:GINS subunit, domain A" CG18013 11-Aug-17 DroID_v2017_08 Drer\gins2 Scer\PSF2 Cele\psf-2 Xtro\gins2 Mmus\Gins2 Hsap\GINS2 DRSC00516 IE 2.123951156 0.970750155 2.543377399 1.346589113 -0.566711336 -1.002815819 FBgn0060381 l(3)S134612b lethal (3) S134612b http://flybase.org/reports/FBgn0060381 gene - - - "1346/12, l(3)S134612b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030407 CG2543 - http://flybase.org/reports/FBgn0030407 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001645, InterPro:IPR004101, InterPro:IPR013221, InterPro:IPR018109, InterPro:IPR023600 tetrahydrofolylpolyglutamate synthase activity ; GO:0004326 | inferred from sequence or structural similarity with UniProtKB:Q05932" tetrahydrofolylpolyglutamate biosynthetic process ; GO:0046901 | inferred from sequence or structural similarity with UniProtKB:Q05932 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q05932 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q05932 CG2543 "IPR001645:Folylpolyglutamate synthetase, IPR018109:Folylpolyglutamate synthetase, conserved site, IPR023600:Folylpolyglutamate synthase, eukaryota, IPR004101:Mur ligase, C-terminal, IPR013221:Mur ligase, central" CG2543 11-Aug-17 DroID_v2017_08 Drer\fpgs "Scer\FOL3, Scer\RMA1, Scer\MET7" Cele\F25B5.6 Xtro\fpgs Mmus\Fpgs Hsap\FPGS "lethal,recessive,viable" FBgn0264659 scrub scrub http://flybase.org/reports/FBgn0264659 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - scrub - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0013224 E(hop[Tum]) Enhancer of hop[Tum] http://flybase.org/reports/FBgn0013224 - gene - - - E(hop[Tum]) - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051066 CG31066 - http://flybase.org/reports/FBgn0051066 protein_coding_gene - - - CG31066 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261360 CG42637 - http://flybase.org/reports/FBgn0261360 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245 receptor activity ; GO:0004872 | inferred from sequence or structural similarity with Gyc76C guanylate cyclase activity ; GO:0004383 | inferred from sequence or structural similarity with Gyc76C" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245 cyclic nucleotide biosynthetic process ; GO:0009190 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 cGMP-mediated signaling ; GO:0019934 | inferred from sequence or structural similarity with Gyc76C" integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Gyc76C CG42637 "IPR028082:Periplasmic binding protein-like I, IPR011009:Protein kinase-like domain, IPR000719:Protein kinase domain, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR029787:Nucleotide cyclase, IPR001828:Receptor, ligand binding region" CG42637 11-Aug-17 DroID_v2017_08 "Drer\npr1a, Drer\npr2, Drer\si:dkey-37g12.1, Drer\gc2, Drer\gc3, Drer\gucy2g, Drer\gucy2f, Drer\si:ch73-139e5.4, Drer\npr1b, Drer\npr3, Drer\gucy2c, Drer\ints3" - "Cele\odr-1, Cele\gcy-17, Cele\gcy-11, Cele\gcy-2, Cele\gcy-15, Cele\gcy-3, Cele\gcy-12, Cele\gcy-5, Cele\gcy-1, Cele\gcy-20, Cele\gcy-9, Cele\gcy-28, Cele\daf-11, Cele\gcy-6, Cele\gcy-23, Cele\gcy-25, Cele\gcy-7, Cele\gcy-21, Cele\gcy-19, Cele\gcy-13, Cele\gcy-8, Cele\gcy-29, Cele\gcy-14, Cele\gcy-27, Cele\gcy-4, Cele\Y92H12A.4, Cele\gcy-22, Cele\gcy-18" "Xtro\npr3, Xtro\gucy2c, Xtro\gucy2d, Xtro\gucy2f, Xtro\npr1" "Mmus\Gucy2g, Mmus\Npr2, Mmus\Gucy2f, Mmus\Gucy2c, Mmus\Ints3, Mmus\Npr1, Mmus\Gucy2d, Mmus\Npr3, Mmus\Gucy2e" "Hsap\GUCY2C, Hsap\NPR2, Hsap\NPR1, Hsap\GUCY2F, Hsap\GUCY2D, Hsap\NPR3, Hsap\INTS3" FBgn0038730 CG6300 - http://flybase.org/reports/FBgn0038730 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 bioluminescence ; GO:0008218 | inferred from electronic annotation with InterPro:IPR027380 - CG6300 "IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site, IPR027380:Luciferase, N-terminal domain, IPR025110:AMP-binding enzyme C-terminal domain" CG6300 11-Aug-17 DroID_v2017_08 "Drer\acsf3, Drer\acsbg1" Scer\PCS60 "Cele\acs-14, Cele\acs-10, Cele\C25G6.3, Cele\acs-9, Cele\mec-18, Cele\acs-6, Cele\acs-7, Cele\C32E8.6" Xtro\acsf3 "Mmus\Acsf3, Mmus\Acsbg1" "Hsap\ACSF3, Hsap\ACSBG1" DRSC16014 IK -0.226074953 2.040708663 0.507068893 -0.321835425 1.830274522 1.075702349 FBgn0014411 Vps26 Vacuolar protein sorting 26 http://flybase.org/reports/FBgn0014411 - protein_coding_gene protein transporter activity ; GO:0008565 | contributes_to inferred from sequence or structural similarity with SGD:S000003589 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000260563 "regulation of BMP signaling pathway ; GO:0030510 | NOT inferred from mutant phenotype retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with SGD:S000003589 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000260563 smoothened signaling pathway ; GO:0007224 | NOT inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN000260564" "retromer, cargo-selective complex ; GO:0030906 | inferred from sequence or structural similarity with SGD:S000003589 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000260563 retromer complex ; GO:0030904 | inferred from direct assay retromer complex ; GO:0030904 | inferred from biological aspect of ancestor with PANTHER:PTN000260564 endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000003589" "EG:63B12.8, 131F2S, anon-sts13, ESTS:131F2S, Vps26, dvps26, Dvps26, CG14804, DmVps26, vps26, dVps26" IPR028934:Vacuolar protein sorting protein 26 related CG14804 11-Aug-17 DroID_v2017_08 "Drer\vps26bl, Drer\vps26a, Drer\jam3a, Drer\vps26b" Scer\PEP8 Cele\vps-26 "Xtro\vps26b, Xtro\vps26a" "Mmus\Vps26b, Mmus\Vps26a" "Hsap\VPS26B, Hsap\VPS26A" "neurophysiology defective,progressive,visible,partially lethal - majority die,some die during pupal stage" "photoreceptor cell,progressive,rhabdomere,endosome,lysosome,trichogen cell,mesothoracic tergum" FBgn0036040 CG6749 - http://flybase.org/reports/FBgn0036040 protein_coding_gene - - - CG6749 "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG6749 11-Aug-17 DroID_v2017_08 "Drer\chadlb, Drer\chadla, Drer\chad" Scer\CYR1 "Cele\tol-1, Cele\lron-1, Cele\lron-2, Cele\pan-1, Cele\lron-9" "Xtro\chadl, Xtro\LOC100488097" "Mmus\Gp5, Mmus\Chad, Mmus\Chadl, Mmus\Cpn2, Mmus\Tril" "Hsap\CHAD, Hsap\CPN2, Hsap\TRIL, Hsap\IGFALS, Hsap\CHADL" viable FBgn0085384 CG34355 - http://flybase.org/reports/FBgn0085384 protein_coding_gene - - - "CG34355, CG12492, CG13818, lincRNA.840" "IPR005018:DOMON domain, IPR019545:DM13 domain" CG34355 11-Aug-17 DroID_v2017_08 - - "Cele\W01C8.5, Cele\F59F5.7, Cele\H06A10.1, Cele\M03A1.8" - - - FBgn0027562 CG10345 - http://flybase.org/reports/FBgn0027562 - protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "BcDNA, BcDNA:GH08773, CG10345" "IPR002159:CD36 family, IPR005428:CD36/scavenger receptor class B member 1" CG10345 11-Aug-17 DroID_v2017_08 "Drer\cd36, Drer\LOC564077, Drer\scarb2, Drer\scarb1" - "Cele\scav-3, Cele\scav-2, Cele\scav-1" "Xtro\scarb2, Xtro\cd36, Xtro\scarb1" "Mmus\Cd36, Mmus\Scarb2, Mmus\Scarb1" "Hsap\CD36, Hsap\SCARB2, Hsap\SCARB1" "viable,fertile" FBgn0033809 CG4630 - http://flybase.org/reports/FBgn0033809 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG4630 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG4630 11-Aug-17 DroID_v2017_08 "Drer\slc22a4, Drer\si:dkey-166k12.1, Drer\slc22a21, Drer\zmp:0000001102, Drer\slc22a7a, Drer\slc22a7b.1, Drer\slc22a15, Drer\zgc:153639, Drer\slc22a2, Drer\slc22a5, Drer\slc22a7b.3" "Scer\GIT1, Scer\HXT2, Scer\PHO84, Scer\HXT9, Scer\HXT5, Scer\HXT1" "Cele\C53B4.1, Cele\oct-1, Cele\C46C2.2, Cele\ZK892.3, Cele\Y66D12A.13, Cele\Y57G11C.23, Cele\Y51A2D.18, Cele\oct-2" "Xtro\slc22a5, Xtro\slc22a13, Xtro\slc22a15.2, Xtro\slc22a4" "Mmus\Slc22a12, Mmus\Slc22a13, Mmus\Slc22a4, Mmus\Slc22a3, Mmus\Slc22a21, Mmus\Slc22a1, Mmus\Slc22a5" "Hsap\SLC22A3, Hsap\SLC22A4, Hsap\SLC22A5" "partially lethal - majority die,some die during pupal stage" FBgn0002515 l(3)Sp9 lethal (3) Sp9 http://flybase.org/reports/FBgn0002515 - gene - - - l(3)Sp9 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004532 l(4)102ABh lethal (4) 102ABh http://flybase.org/reports/FBgn0004532 - gene - - - "l(4)ABh, l(4)ST-3, l(4)25, l(4)102ABh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266302 CR44967 - http://flybase.org/reports/FBgn0266302 non_protein_coding_gene - - - CR44967 - CR44967 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043877 mecE mechanosensory E http://flybase.org/reports/FBgn0043877 gene - - - mecE - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039436 TwdlB TweedleB http://flybase.org/reports/FBgn0039436 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlB, CG6478" IPR004145:Domain of unknown function DUF243 CG6478 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028264 l(2)46Ck lethal (2) 46Ck http://flybase.org/reports/FBgn0028264 gene - - - "Q, l(2)46Ck" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0261284 bou boudin http://flybase.org/reports/FBgn0261284 protein_coding_gene - "regulation of tube architecture, open tracheal system ; GO:0035152 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from direct assay cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN001048184 anchored component of plasma membrane ; GO:0046658 | inferred from direct assay "bou, CG14430, JNXL4, l(1)jnL4, jnL4, l(1)6Ea, BcDNA:RE28342" - CG14430 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082633 S(CycE[JP])2.4 S(CycE[JP])2.4 http://flybase.org/reports/FBgn0082633 gene - - - S(CycE[JP])2.4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0044813 T:ZnF-su(Hw) Zinc-finger DNA-binding domain of su(Hw) http://flybase.org/reports/FBgn0044813 engineered_tag - - - "T:ZnF-su(Hw), T:su(Hw)" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035410 CG14964 - http://flybase.org/reports/FBgn0035410 protein_coding_gene structural molecule activity conferring elasticity ; GO:0097493 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 structural constituent of muscle ; GO:0008307 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 muscle alpha-actinin binding ; GO:0051371 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 sarcomere organization ; GO:0045214 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 actin filament organization ; GO:0007015 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 striated muscle myosin thick filament assembly ; GO:0071688 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 striated muscle contraction ; GO:0006941 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 Z disc ; GO:0030018 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 muscle myosin complex ; GO:0005859 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 M band ; GO:0031430 | inferred from biological aspect of ancestor with PANTHER:PTN001790569 "CT34810, CG14964" "IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003598:Immunoglobulin subtype 2" CG14964 11-Aug-17 DroID_v2017_08 "Drer\igfn1.1, Drer\myom2a, Drer\igfn1.4, Drer\obsl1b, Drer\mybpc2a, Drer\mybpc1, Drer\igfn1.2, Drer\obsl1a, Drer\myom1a, Drer\mybpc2b, Drer\mybpha, Drer\ttn.2, Drer\mybphb, Drer\mybpc3, Drer\ttnb, Drer\igfn1.3, Drer\myom1b, Drer\myom3" - "Cele\sax-3, Cele\ttn-1" "Xtro\myom1, Xtro\myom2, Xtro\mybpc3, Xtro\mybph" "Mmus\Mybpc1, Mmus\Myom1, Mmus\Myom3, Mmus\Mybphl, Mmus\Myom2, Mmus\Mybpc3, Mmus\Mybph, Mmus\Obsl1, Mmus\Ttn, Mmus\Igfn1, Mmus\Mybpc2" "Hsap\TTN, Hsap\MYOM3, Hsap\MYOM2, Hsap\MYBPHL, Hsap\MYBPC2, Hsap\MYBPH, Hsap\MYBPC3, Hsap\MYBPC1, Hsap\IGFN1, Hsap\MYOM1, Hsap\OBSL1, Hsap\IGSF22" viable FBgn0038465 Irc Immune-regulated catalase http://flybase.org/reports/FBgn0038465 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 catalase activity ; GO:0004096 | inferred from direct assay oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 cellular oxidant detoxification ; GO:0098869 | inferred from direct assay - "IRC, CG8913, Irc" "IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal" CG8913 11-Aug-17 DroID_v2017_08 "Drer\ptgs1, Drer\ptgs2a, Drer\tpo, Drer\ptgs2b, Drer\igsf9bb" "Scer\GCR2, Scer\TCM62, Scer\YHR140W, Scer\SLA1, Scer\SEC72, Scer\GDS1, Scer\GDH2" "Cele\T06D8.10, Cele\C46A5.4, Cele\K10B4.1, Cele\F09F3.5, Cele\R08F11.7, Cele\skpo-1" "Xtro\epx, Xtro\ptgs1, Xtro\tpo, Xtro\pxdn, Xtro\mpo, Xtro\ptgs2" "Mmus\Lpo, Mmus\Ptgs2, Mmus\Tpo, Mmus\Epx, Mmus\Mpo, Mmus\Ptgs1, Mmus\Pxdn" "Hsap\PTGS2, Hsap\PXDNL, Hsap\TPO, Hsap\EPX, Hsap\SCN10A, Hsap\PTGS1, Hsap\PXDN, Hsap\LPO, Hsap\MPO" "chemical sensitive,immune response defective,short lived,conditional" FBgn0001062 Fs(3)Pil Female sterile (3) Pilis http://flybase.org/reports/FBgn0001062 - gene - - - "Fs(3)Pilis, Fs(3)Sz20, Fs(3)Pil" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0020574 anon-59Ck anon-59Ck http://flybase.org/reports/FBgn0020574 - gene - - - anon-59Ck - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024602 oop out of place http://flybase.org/reports/FBgn0024602 - gene molecular_function ; GO:0003674 | no biological data available Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available oop - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "Bolwig organ,Bolwig nerve" FBgn0005304 ms(1)6S male sterile (1) 6S http://flybase.org/reports/FBgn0005304 - gene - - - ms(1)6S - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "spermatozoon,spermatid axoneme,Nebenkern derivative,acrosomal granule,spermatid & nucleus" FBgn0262251 mir-977 mir-977 stem loop http://flybase.org/reports/FBgn0262251 miRNA_gene - - - "miR-977, dme-mir-977, 977, mir-977, CR42958" - CR42958 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible" "eye,wing" FBgn0266978 CR45429 - http://flybase.org/reports/FBgn0266978 non_protein_coding_gene - - - CR45429 - CR45429 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032699 CG10383 - http://flybase.org/reports/FBgn0032699 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR012908" sleep ; GO:0030431 | inferred from expression pattern determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype - CG10383 "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR029058:Alpha/Beta hydrolase fold, IPR012908:GPI inositol-deacylase PGAP1-like" CG10383 11-Aug-17 DroID_v2017_08 Drer\serac1 - Cele\F17H10.1 Xtro\serac1 Mmus\Serac1 Hsap\SERAC1 "long lived,viable" FBgn0001901 l(2)22Ab lethal (2) 22Ab http://flybase.org/reports/FBgn0001901 - gene - - - "l(2)neh-15, l(2)neh15, l(2)22Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0086367 t tan http://flybase.org/reports/FBgn0086367 protein_coding_gene beta-alanyl-histamine hydrolase activity ; GO:0031964 | inferred from direct assay beta-alanyl-dopamine hydrolase activity ; GO:0003832 | inferred from direct assay beta-alanyl-dopamine hydrolase activity ; GO:0003832 | inferred from mutant phenotype hydrolase activity ; GO:0016787 | inferred from direct assay adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype histamine biosynthetic process ; GO:0001694 | inferred from direct assay cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype dopamine biosynthetic process ; GO:0042416 | inferred from direct assay histamine metabolic process ; GO:0001692 | inferred from mutant phenotype visual perception ; GO:0007601 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG12120, t, tan, Tan" IPR005079:Peptidase C45 CG12120 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067881 Mod(Prat:bw)2-1 Mod(Prat:bw)2-1 http://flybase.org/reports/FBgn0067881 gene - - - Mod(Prat:bw)2-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0267620 CR45958 - http://flybase.org/reports/FBgn0267620 non_protein_coding_gene - - - CR45958 - CR45958 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020288 l(2)k06407 lethal (2) k06407 http://flybase.org/reports/FBgn0020288 - gene - - - "lp, l(2)k06407" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039979 CR40282 - http://flybase.org/reports/FBgn0039979 pseudogene_attribute - - - "CG17706, CG40282, CR40282" - CR40282 11-Aug-17 DroID_v2017_08 - - - - - - DRSC07814 I 1.836631432 -0.577866393 1.075018821 1.125845627 -0.665061477 -0.836474188 FBgn0035886 Jon66Ci Jonah 66Ci http://flybase.org/reports/FBgn0035886 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 endopeptidase activity ; GO:0004175 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "66C, CG7118, SP171, Jon66C, Jon66Ci" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG7118 11-Aug-17 DroID_v2017_08 Drer\masp2 - - - "Mmus\C1s1, Mmus\C1s2, Mmus\Cela1" "Hsap\PROC, Hsap\C1S, Hsap\KLK3" viable FBgn0037618 ouib ouija board http://flybase.org/reports/FBgn0037618 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype positive regulation of ecdysteroid biosynthetic process ; GO:0045998 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay instar larval development ; GO:0002168 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0003700 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 "CG11762, i36, ouib" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11762 11-Aug-17 DroID_v2017_08 "Drer\LOC101883087, Drer\znf341, Drer\znfl2a, Drer\bcl6ab, Drer\znf770" - "Cele\klf-3, Cele\ztf-23, Cele\lin-29, Cele\blmp-1, Cele\Y37F4.6, Cele\eor-1, Cele\M03D4.4, Cele\Y55F3AM.14" - "Mmus\Zfp445, Mmus\Zfp341, Mmus\Zfp24, Mmus\Zscan5b, Mmus\Rbak, Mmus\Zfp369, Mmus\Zfp110, Mmus\Zfp810" "Hsap\ZNF221, Hsap\ZNF560, Hsap\ZNF701, Hsap\ZNF8, Hsap\ZNF341, Hsap\ZNF784, Hsap\ZNF284, Hsap\ZNF281" DRSC14376 K 0.378752336 -0.699848862 -0.970844117 -0.166193664 1.759686141 -0.060889491 FBgn0036451 CG9425 - http://flybase.org/reports/FBgn0036451 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571, InterPro:IPR007087" - - CG9425 "IPR000571:Zinc finger, CCCH-type, IPR011990:Tetratricopeptide-like helical domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013087:Zinc finger C2H2-type, IPR026122:Putative helicase MOV-10, IPR015943:WD40/YVTN repeat-like-containing domain" CG9425 11-Aug-17 DroID_v2017_08 "Drer\mov10b.2, Drer\si:dkey-97a13.6, Drer\helz, Drer\mov10a, Drer\zgc:154086, Drer\helz2, Drer\mov10b.1" Scer\NAM7 "Cele\C44H9.4, Cele\C05C10.2" "Xtro\helz, Xtro\mov10, Xtro\mov10l1" "Mmus\Mov10l1, Mmus\Helz2, Mmus\Helz, Mmus\Mov10" "Hsap\HELZ2, Hsap\MOV10, Hsap\MOV10L1, Hsap\HELZ" heart primordium FBgn0030466 CG15744 - http://flybase.org/reports/FBgn0030466 protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000832, InterPro:IPR001879" G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000832 cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000832 "CT35992, CG15744, Q7KV24_DROME" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR000832:GPCR, family 2, secretin-like, IPR001879:GPCR, family 2, extracellular hormone receptor domain, IPR003591:Leucine-rich repeat, typical subtype, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR017981:GPCR, family 2-like, IPR032675:Leucine-rich repeat domain, L domain-like, IPR013783:Immunoglobulin-like fold, IPR001611:Leucine-rich repeat" CG15744 11-Aug-17 DroID_v2017_08 "Drer\gabrz, Drer\lgi2a, Drer\adgra2, Drer\lgi1a, Drer\lgi1b, Drer\lgi3, Drer\adgra1a, Drer\lgi2b" - Cele\pxn-1 "Xtro\lgi1, Xtro\adgra2, Xtro\lgi4, Xtro\lgi2, Xtro\adgra3" "Mmus\Adgra1, Mmus\Lgi1, Mmus\Lgi4, Mmus\Lgi2, Mmus\Lgi3, Mmus\Adgra2, Mmus\Adgra3" "Hsap\ADGRA3, Hsap\ADGRA2, Hsap\LGI3, Hsap\ADGRA1, Hsap\LGI2, Hsap\LGI4, Hsap\ADGRG4, Hsap\LGI1" viable FBgn0011777 l(2)DTS18WF lethal (2) DTS18 Wright & Falke http://flybase.org/reports/FBgn0011777 FBgn0005147 gene - - - "DTS18, l(2)DTS18, l(2)DTS18WF" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,dominant,heat sensitive,female sterile" FBgn0040332 EY2-5 EY2-5 http://flybase.org/reports/FBgn0040332 gene - - - EY2-5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082993 snoRNA:Psi28S-1936 snoRNA:Psi28S-1936 http://flybase.org/reports/FBgn0082993 snoRNA_gene - - - "snoRNA:Psi28S-1936, psi28s-1936, CR34530" - CR34530 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083062 sgo smeagol http://flybase.org/reports/FBgn0083062 gene - meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype - "sgo, Sgo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern,spindle & meiotic cell cycle | male,contractile ring & meiotic cell cycle | male,spermatid & nucleus | supernumerarymbc-R1),spindle & meiotic cell cycle | malembc-R1),contractile ring & meiotic cell cycle | malembc-R1)" FBgn0039768 CG15533 - http://flybase.org/reports/FBgn0039768 protein_coding_gene sphingomyelin phosphodiesterase activity ; GO:0004767 | inferred from electronic annotation with InterPro:IPR011160 sphingomyelin catabolic process ; GO:0006685 | inferred from electronic annotation with InterPro:IPR011160 - "aSMase, CG15533" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR008139:Saposin B type domain, IPR011160:Sphingomyelin phosphodiesterase, IPR029052:Metallo-dependent phosphatase-like" CG15533 11-Aug-17 DroID_v2017_08 Drer\smpd1 Scer\PPN1 "Cele\asm-3, Cele\asm-1, Cele\ZK856.5, Cele\asm-2" - Mmus\Smpd1 Hsap\SMPD1 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0082950 snoRNA:Me18S-G1952 snoRNA:Me18S-G1952 http://flybase.org/reports/FBgn0082950 snoRNA_gene - - - "snoRNA:Me18S-G1952, Me18S-G1952, CR34536" - CR34536 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060787 l(3)S059508 lethal (3) S059508 http://flybase.org/reports/FBgn0060787 gene - - - "0595/08, l(3)S059508" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033002 CG17589 - http://flybase.org/reports/FBgn0033002 protein_coding_gene - - - CG17589 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265891 CR44680 - http://flybase.org/reports/FBgn0265891 non_protein_coding_gene - - - CR44680 - CR44680 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033349 CG8243 - http://flybase.org/reports/FBgn0033349 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 GTPase activator activity ; GO:0005096 | inferred from sequence model regulation of GTPase activity ; GO:0043087 | inferred from sequence model cellular_component ; GO:0005575 | no biological data available "CG8243, gap40, SMAP" IPR001164:Arf GTPase activating protein CG8243 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000000660, Drer\adap2, Drer\smap1, Drer\arap3, Drer\LOC100005008, Drer\smap2, Drer\zgc:92360, Drer\si:ch211-135f11.1" "Scer\GTS1, Scer\AGE2" Cele\W09D10.1 "Xtro\adap1, Xtro\smap2, Xtro\smap1, Xtro\adap1" "Mmus\Adap1, Mmus\Smap2, Mmus\Arap2, Mmus\Adap2, Mmus\Smap1, Mmus\Arap3, Mmus\Arap1" "Hsap\ADAP2, Hsap\SMAP2, Hsap\ARAP3, Hsap\ARAP1, Hsap\ARAP2, Hsap\ADAP1, Hsap\SMAP1" lethal FBgn0267901 CR46189 - http://flybase.org/reports/FBgn0267901 pseudogene_attribute - - - "CR46189, CG12717-related" - CR46189 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001217 Hsc70-2 Heat shock protein cognate 2 http://flybase.org/reports/FBgn0001217 - protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P38646 protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P38646 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P38646 "Hsc70-2, Hsc70, HSC-70, HSC70, hsc70, dhsc70, HSC2, hsc2, Hsc2, Hsc70.2, CG7756, Hsc-2, HSC70-2, HSP7B_DROME" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG7756 11-Aug-17 DroID_v2017_08 "Drer\hsp70.2, Drer\nckap1, Drer\si:ch211-199o1.2, Drer\hspa12a, Drer\si:dkey-4p15.3, Drer\hspa8, Drer\hspa12b, Drer\hsp70.1, Drer\hspa13, Drer\hspa14, Drer\hsc70, Drer\hspa5, Drer\hsp70l" "Scer\SSQ1, Scer\SSB1, Scer\SSA1, Scer\SSZ1, Scer\SSA4, Scer\SSB2, Scer\SSA3, Scer\SSA2, Scer\KAR2" "Cele\hsp-70, Cele\hsp-1, Cele\hsp-3, Cele\gex-3, Cele\F11F1.1, Cele\F44E5.5, Cele\F44E5.4, Cele\hsp-4" "Xtro\hspa12b, Xtro\hspa8, Xtro\hspa2, Xtro\hspa1b, Xtro\nckap1, Xtro\hspa13, Xtro\hspa1l, Xtro\hsp70, Xtro\nckap1l, Xtro\hspa14, Xtro\hspa1a, Xtro\hspa5" "Mmus\Hspa1b, Mmus\Nckap1l, Mmus\Hspa13, Mmus\Hspa14, Mmus\Hspa12b, Mmus\Nckap1, Mmus\Hspa5, Mmus\Hspa8, Mmus\Hspa12a, Mmus\Hspa2, Mmus\Hspa1a, Mmus\Hspa1l" "Hsap\HSPA1A, Hsap\HSPA6, Hsap\HSPA1B, Hsap\HSPA5, Hsap\HSPA12A, Hsap\HSPA12B, Hsap\HSPA8, Hsap\HSPA14, Hsap\NCKAP1, Hsap\NCKAP1L, Hsap\HSPA2, Hsap\HSPA13, Hsap\HSPA1L" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0017438 anon-28Ca anon-28Ca http://flybase.org/reports/FBgn0017438 - gene - - - anon-28Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029700 CG15576 - http://flybase.org/reports/FBgn0029700 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15576 - CG15576 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0044388 Scim6 Sensitized chromosome inheritance modifier 6 http://flybase.org/reports/FBgn0044388 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0262593 Shab Shaker cognate b http://flybase.org/reports/FBgn0262593 protein_coding_gene delayed rectifier potassium channel activity ; GO:0005251 | inferred from direct assay voltage-gated potassium channel activity ; GO:0005249 | traceable author statement "protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR003968, InterPro:IPR003971, InterPro:IPR028325 potassium ion transport ; GO:0006813 | traceable author statement action potential ; GO:0001508 | inferred from mutant phenotype positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype regulation of heart contraction ; GO:0008016 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype" "voltage-gated potassium channel complex ; GO:0008076 | inferred from electronic annotation with InterPro:IPR003968, InterPro:IPR003971, InterPro:IPR028325 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with Sh voltage-gated potassium channel complex ; GO:0008076 | traceable author statement" "CG43128, Shab, shab, dShab, CG1066, Kv2, CG9965, shb, K[[v]]2" "IPR028325:Voltage-gated potassium channel, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029058:Alpha/Beta hydrolase fold, IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR003968:Potassium channel, voltage dependent, Kv, IPR003971:Potassium channel, voltage dependent, Kv9, IPR005821:Ion transport domain" CG43128 11-Aug-17 DroID_v2017_08 "Drer\kcns3b, Drer\kcnv2b, Drer\si:rp71-39b20.4, Drer\kcng4a, Drer\kcng1, Drer\kcnv2a, Drer\kcng2, Drer\kcnb2, Drer\kcnc1b, Drer\kcnf1a, Drer\si:dkey-201i6.2, Drer\kcns3a, Drer\kcnb1, Drer\kcnc2, Drer\si:dkey-43k4.5, Drer\kcnc3b, Drer\kcng4b, Drer\kcnc4, Drer\kcnc1a, Drer\kcng3, Drer\kcnc3a, Drer\kcnf1b, Drer\si:dkey-192j17.1" - "Cele\C32C4.1, Cele\exp-2, Cele\kvs-1, Cele\kvs-3, Cele\kvs-5, Cele\kvs-4" "Xtro\kcnf1, Xtro\kcng2, Xtro\kcng4, Xtro\kcns1, Xtro\kcnc4, Xtro\kcnb1, Xtro\kcng1, Xtro\kcnv1, Xtro\kcns3, Xtro\kcnb2, Xtro\kcnv2" "Mmus\Kcnc4, Mmus\Kcnv2, Mmus\Kcns2, Mmus\Kcng2, Mmus\Kcng1, Mmus\Kcnb2, Mmus\Kcng4, Mmus\Kcnc3, Mmus\Kcnb1, Mmus\Kcnf1, Mmus\Kcnv1, Mmus\Kcnc1, Mmus\Kcns3, Mmus\Kcnc2, Mmus\Kcng3, Mmus\Kcns1" "Hsap\KCNG1, Hsap\KCNG2, Hsap\KCNC3, Hsap\KCNG4, Hsap\KCNS3, Hsap\KCNS1, Hsap\KCNB1, Hsap\KCNV1, Hsap\KCNV2, Hsap\KCNC1, Hsap\KCNC4, Hsap\KCNC2, Hsap\KCNG3, Hsap\KCNS2, Hsap\KCNF1, Hsap\KCNB2" " embryonic stage | late , pupal stage " FBgn0058358 CG40358 - http://flybase.org/reports/FBgn0058358 protein_coding_gene - - - CG40358 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053427 5SrRNA:CR33427 5SrRNA:CR33427 http://flybase.org/reports/FBgn0053427 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33427, 5SrRNA:CR33427" - CR33427 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266416 CR45056 - http://flybase.org/reports/FBgn0266416 non_protein_coding_gene - - - CR45056 - CR45056 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042693 PP2A-B' PP2A-B' http://flybase.org/reports/FBgn0042693 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from electronic annotation with InterPro:IPR002554 protein phosphatase regulator activity ; GO:0019888 | non-traceable author statement protein phosphatase regulator activity ; GO:0019888 | inferred from sequence or structural similarity signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002554 autophagy ; GO:0006914 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype sex comb development ; GO:0045498 | NOT inferred from mutant phenotype synaptic vesicle localization ; GO:0097479 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | non-traceable author statement protein phosphatase type 2A complex ; GO:0000159 | inferred from electronic annotation with InterPro:IPR002554 protein phosphatase type 2A complex ; GO:0000159 | inferred from sequence or structural similarity "PP2A-B', wrd, CG7913, B56-1, PP2A, CG7901, i234, B'/PR61, PP2A B', dPP2A,B', BcDNA:GM05554, anon-WO0118547.420, dPP2A, PP2A-B, dB56-1, CG 7913, PP2A[B'-1], pp2A-B', dPP2A-B56-1, Wrd, B'" "IPR002554:Protein phosphatase 2A, regulatory B subunit, B56, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG7913 11-Aug-17 DroID_v2017_08 "Drer\ppp2r5ca, Drer\ppp2r5d, Drer\ppp2r5eb, Drer\ppp2r5b, Drer\ppp2r5cb, Drer\ppp2r5a, Drer\ppp2r5ea" Scer\RTS1 "Cele\pptr-2, Cele\pptr-1" "Xtro\ppp2r5e, Xtro\ppp2r5c, Xtro\ppp2r5b, Xtro\ppp2r5a" "Mmus\Ppp2r5a, Mmus\Ppp2r5d, Mmus\Ppp2r5c, Mmus\Ppp2r5b, Mmus\Ppp2r5e" "Hsap\PPP2R5C, Hsap\PPP2R5B, Hsap\PPP2R5E, Hsap\PPP2R5D, Hsap\PPP2R5A" "viable,female fertile,male fertile,fertile,short lived,partially lethal - majority die,lethal,visible,neuroanatomy defective,recessive,neurophysiology defective" "salivary gland,NMJ bouton | larval stage,neuromuscular junction | larval stage,bouton & neuromuscular junction | larval stage,microtubule & neuromuscular junction | larval stage,bouton & neuromuscular junction | larval stageDG4),neuromuscular junction,bouton" FBgn0037469 Dpck Dephospho-CoA kinase http://flybase.org/reports/FBgn0037469 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001977 dephospho-CoA kinase activity ; GO:0004140 | inferred from sequence or structural similarity with SGD:S000002604 dephospho-CoA kinase activity ; GO:0004140 | inferred from biological aspect of ancestor with PANTHER:PTN000075336 coenzyme A biosynthetic process ; GO:0015937 | inferred from sequence or structural similarity with SGD:S000002604 coenzyme A biosynthetic process ; GO:0015937 | inferred from biological aspect of ancestor with PANTHER:PTN000075336 endomembrane system ; GO:0012505 | inferred from direct assay "CG1939, Dpck, DPCK, dDPCK" "IPR001977:Dephospho-CoA kinase, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1939 11-Aug-17 DroID_v2017_08 "Drer\dcakd, Drer\coasy" Scer\CAB5 Cele\T05G5.5 "Xtro\dcakd, Xtro\coasy" "Mmus\Coasy, Mmus\Dcakd" "Hsap\DCAKD, Hsap\COASY" "viable,visible,fertile" "trichogen cell,mesothoracic tergum" FBgn0261722 fwe flower http://flybase.org/reports/FBgn0261722 protein_coding_gene calcium channel activity ; GO:0005262 | inferred from direct assay cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from direct assay regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype positive regulation of neuron apoptotic process ; GO:0043525 | inferred from mutant phenotype spanning component of plasma membrane ; GO:0044214 | inferred from direct assay integral component of synaptic vesicle membrane ; GO:0030285 | inferred from direct assay "dFwe, CG6151, anon-WO0118547.242, fwe, flower" IPR019365:TVP18/Calcium channel flower CG6151 11-Aug-17 DroID_v2017_08 Drer\si:ch73-209e20.5 Scer\TVP18 Cele\F20D1.1 - Mmus\Cacfd1 Hsap\CACFD1 FBgn0265653 CR44460 - http://flybase.org/reports/FBgn0265653 non_protein_coding_gene - - - "lincRNA.351, CR44460" - CR44460 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032645 CG15142 - http://flybase.org/reports/FBgn0032645 protein_coding_gene - - - CG15142 IPR017266:Cyclin-dependent kinase 2-associated protein 1/2 CG15142 11-Aug-17 DroID_v2017_08 Drer\cdk2ap2 - Cele\Y43F4B.10 "Xtro\cdk2ap1, Xtro\cdk2ap2" "Mmus\Cdk2ap1, Mmus\Cdk2ap2" "Hsap\CDK2AP2, Hsap\CDK2AP1" partially lethal - majority die FBgn0003004 oph ophthalmopedia http://flybase.org/reports/FBgn0003004 - gene - - - oph - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye disc,eye" FBgn0013699 mt:tRNA:Leu-TAA mitochondrial transfer RNA:Leucine-TAA http://flybase.org/reports/FBgn0013699 FBgn0002867 tRNA_gene - - - "CR34068, mtdbD00006298, mt:tRNA:Leu-TAA, mt:tRNA:L:UUR" - CR34068 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265948 CR44735 - http://flybase.org/reports/FBgn0265948 non_protein_coding_gene - - - "lincRNA.162, CR44735" - CR44735 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046708 GIIID GIIID http://flybase.org/reports/FBgn0046708 gene phospholipase A2 activity ; GO:0004623 | non-traceable author statement - extracellular region ; GO:0005576 | non-traceable author statement "dGIIID, GIIID" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036240 CG6928 - http://flybase.org/reports/FBgn0036240 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 CG6928 "IPR011547:SLC26A/SulP transporter domain, IPR001902:SLC26A/SulP transporter, IPR002645:STAS domain" CG6928 11-Aug-17 DroID_v2017_08 "Drer\slc26a1, Drer\si:ch211-117c9.2, Drer\slc26a11, Drer\slc26a3.1, Drer\slc26a3.2, Drer\slc26a6, Drer\slc26a10, Drer\slc26a2, Drer\slc26a4, Drer\slc26a5, Drer\slc26a6l" "Scer\SUL2, Scer\YGR125W, Scer\YPR003C, Scer\SUL1" "Cele\sulp-2, Cele\sulp-8, Cele\sulp-4, Cele\sulp-6, Cele\sulp-1, Cele\sulp-3, Cele\sulp-5, Cele\sulp-7" "Xtro\slc26a9, Xtro\slc26a5, Xtro\slc26a11, Xtro\slc26a6, Xtro\slc26a1, Xtro\slc26a2, Xtro\slc26a4, Xtro\slc26a7, Xtro\slc26a10" "Mmus\Slc26a4, Mmus\Slc26a7, Mmus\Slc26a8, Mmus\Slc26a11, Mmus\Slc26a2, Mmus\Slc26a10, Mmus\Slc26a3, Mmus\Slc26a5, Mmus\Slc26a1, Mmus\Slc26a6, Mmus\Slc26a9" "Hsap\SLC26A5, Hsap\SLC26A1, Hsap\SLC26A9, Hsap\SLC26A8, Hsap\SLC26A4, Hsap\SLC26A3, Hsap\SLC26A2, Hsap\SLC26A10, Hsap\SLC26A6, Hsap\SLC26A7, Hsap\SLC26A11" "viable,fertile" FBgn0014991 l(2)46Dg lethal (2) 46Dg http://flybase.org/reports/FBgn0014991 - gene - - - "XIII, l(2)46Dg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0083154 S(smoDN)166 Suppressor of smoDN 166 http://flybase.org/reports/FBgn0083154 gene - - - S(smoDN)166 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044473 EP1534 EP1534 http://flybase.org/reports/FBgn0044473 gene - - - EP1534 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective FBgn0052374 CG32374 - http://flybase.org/reports/FBgn0052374 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP148, CG8528, CG32374" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG32374 11-Aug-17 DroID_v2017_08 - - "Cele\try-1, Cele\svh-1" Xtro\gzma "Mmus\Klk1b11, Mmus\Prss36, Mmus\Prss55, Mmus\Prss53" "Hsap\PRSS57, Hsap\PRSS36, Hsap\PRSS53" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0053396 5SrRNA:CR33396 5SrRNA:CR33396 http://flybase.org/reports/FBgn0053396 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33396, 5SrRNA:CR33396" - CR33396 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044817 Ste12DOR Stellate 12D orphon http://flybase.org/reports/FBgn0044817 protein_coding_gene "protein kinase regulator activity ; GO:0019887 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150" - "protein kinase CK2 complex ; GO:0005956 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150" "SC-1, Ste, CG32616, Ste12DOR, SteDOR" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG32616 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0051518 tRNA:Gly-TCC-1-4 transfer RNA:Glycine-TCC 1-4 http://flybase.org/reports/FBgn0051518 tRNA_gene GGA codon-amino acid adaptor activity ; GO:0033463 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033463 cytosol ; GO:0005829 | inferred by curator from GO:0033463 "AE002708.trna19-GlyTCC, tRNA[Gly][[GGA]], tRNA:gly:90DE, tRNA:G:90DE, tRNA:G:TCC:AE002708-b, CR31518, chr3R.trna25-GlyTCC, tRNA-Gly-TCC-1-4, tRNA:Gly-TCC-1-4, tRNA:CR31518, GGA" - CR31518 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033499 CG12914 - http://flybase.org/reports/FBgn0033499 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12914 - CG12914 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032286 CG7300 - http://flybase.org/reports/FBgn0032286 protein_coding_gene - - - CG7300 - CG7300 11-Aug-17 DroID_v2017_08 - Scer\NUP100 Cele\H43E16.1 - - - FBgn0034032 CG8195 - http://flybase.org/reports/FBgn0034032 protein_coding_gene - transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN001496175 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000620 CG8195 IPR000620:EamA domain CG8195 11-Aug-17 DroID_v2017_08 Drer\slc35f3a "Scer\THI74, Scer\YML018C" Cele\B0041.5 - Mmus\Slc35f5 Hsap\SLC35F5 viable FBgn0266591 CG45116 - http://flybase.org/reports/FBgn0266591 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45116 - CG45116 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051092 LpR2 Lipophorin receptor 2 http://flybase.org/reports/FBgn0051092 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 lipoprotein particle binding ; GO:0071813 | inferred from physical interaction with Apoltp" positive regulation of lipid transport ; GO:0032370 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "CG4823, CG31092, CG4834, LpR2, LDLR, Lpr2, lpr2" "IPR009030:Growth factor receptor cysteine-rich domain, IPR018097:EGF-like calcium-binding, conserved site, IPR000033:LDLR class B repeat, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG31092 11-Aug-17 DroID_v2017_08 "Drer\lrp12, Drer\LOC100536757, Drer\lrp1bb, Drer\si:dkey-258f14.3, Drer\lrp3, Drer\lrp10, Drer\scospondin, Drer\ldlrad3, Drer\ldlra, Drer\sorl1, Drer\si:dkey-88l16.3, Drer\lrp1ab, Drer\lrp1ba, Drer\vldlr, Drer\lrp8" "Scer\APM1, Scer\YCR100C, Scer\APM3, Scer\YNR065C, Scer\APM2, Scer\VTH1" "Cele\lrp-2, Cele\nid-1, Cele\egg-1, Cele\T13C2.6, Cele\F14B4.1" "Xtro\lrp2, Xtro\lrp8, Xtro\lrp4, Xtro\sorl1, Xtro\lrp1, Xtro\vldlr, Xtro\ldlr" "Mmus\Cd320, Mmus\Lrp1b, Mmus\Lrp12, Mmus\Ldlr, Mmus\Lrp10, Mmus\Vldlr, Mmus\Lrp3, Mmus\Lrp1, Mmus\Sorl1, Mmus\Lrp2, Mmus\Lrp4, Mmus\Lrp8, Mmus\Sspo" "Hsap\LRP2, Hsap\LRP3, Hsap\LRP5L, Hsap\LRP10, Hsap\LRP1, Hsap\LRP4, Hsap\CD320, Hsap\LRP8, Hsap\SORL1, Hsap\LRP12, Hsap\LRP1B, Hsap\VLDLR, Hsap\LDLR" "viable,female sterile,fertile" lipid particle FBgn0266831 CR45293 - http://flybase.org/reports/FBgn0266831 non_protein_coding_gene - - - CR45293 - CR45293 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260321 GSd206 - http://flybase.org/reports/FBgn0260321 gene - - - GSd206 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0266979 CR45430 - http://flybase.org/reports/FBgn0266979 non_protein_coding_gene - - - CR45430 - CR45430 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085534 CG40910 - http://flybase.org/reports/FBgn0085534 protein_coding_gene - - - CG40910 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026742 anon-45Ab anon-45Ab http://flybase.org/reports/FBgn0026742 - gene - - - "CLOT5200, anon-45Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086231 S149 - http://flybase.org/reports/FBgn0086231 gene - - - S149 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030148 CG3106 - http://flybase.org/reports/FBgn0030148 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG3106 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG3106 11-Aug-17 DroID_v2017_08 "Drer\ptpn9a, Drer\ptpn9b, Drer\oacyl" - "Cele\oac-32, Cele\oac-54, Cele\oac-53, Cele\oac-7, Cele\nrf-6, Cele\oac-20, Cele\oac-6, Cele\oac-46, Cele\oac-55, Cele\oac-50, Cele\oac-31, Cele\rhy-1, Cele\oac-39, Cele\oac-3, Cele\ndg-4, Cele\oac-14, Cele\oac-9, Cele\oac-5" "Xtro\LOC101732251, Xtro\LOC100489200, Xtro\ptpn9" "Mmus\Ptpn9, Mmus\Oacyl" Hsap\PTPN9 viable FBgn0060886 l(3)S044729 lethal (3) S044729 http://flybase.org/reports/FBgn0060886 gene - - - "0447/29, l(3)S044729" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0060424 l(3)S127508 lethal (3) S127508 http://flybase.org/reports/FBgn0060424 gene - - - "1275/08, l(3)S127508" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262980 CG43288 - http://flybase.org/reports/FBgn0262980 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43288, lincRNA.945" - CG43288 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261610 CG42699 - http://flybase.org/reports/FBgn0261610 protein_coding_gene - - - "CG42699, CG15770, CG4064" - CG42699 11-Aug-17 DroID_v2017_08 "Drer\cgnl1, Drer\cep162" - - - Mmus\Cep162 Hsap\CEP162 FBgn0060647 l(3)S083805 lethal (3) S083805 http://flybase.org/reports/FBgn0060647 gene - - - "0838/05, l(3)S083805" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065101 snmRNA:204 small non-messenger RNA 204 http://flybase.org/reports/FBgn0065101 non_protein_coding_gene - - - "Dm-204, CR33657, snmRNA:204" - CR33657 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020866 bsd bashed http://flybase.org/reports/FBgn0020866 - gene - - - bsd - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001893 l(2)21Dg lethal (2) 21Dg http://flybase.org/reports/FBgn0001893 - gene - - - "l(2)neh-7, l(2)neh7, l(2)21Dg" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259875 Su(Ste):CR42444 Su(Ste):CR42444 http://flybase.org/reports/FBgn0259875 non_protein_coding_gene - - - "Su(Ste):CR42444, RR41456, CR42444" - CR42444 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021797 l(2)k17003 lethal (2) k17003 http://flybase.org/reports/FBgn0021797 - gene - - - l(2)k17003 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031106 Syx16 Syntaxin 16 http://flybase.org/reports/FBgn0031106 protein_coding_gene "SNAP receptor activity ; GO:0005484 | non-traceable author statement SNAP receptor activity ; GO:0005484 | inferred from physical interaction with αSnap SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Vps45 protein binding ; GO:0005515 | inferred from physical interaction with car, Vps33B" intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 Golgi vesicle transport ; GO:0048193 | inferred from mutant phenotype vesicle docking ; GO:0048278 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 "Golgi membrane ; GO:0000139 | inferred by curator from GO:0005794,GO:0016021 integral component of membrane ; GO:0016021 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity SNARE complex ; GO:0031201 | inferred by curator from GO:0005484 plasma membrane ; GO:0005886 | non-traceable author statement lysosome ; GO:0005764 | inferred from direct assay Golgi trans cisterna ; GO:0000138 |" "Syx16, dSyx16, DmSyx16, CG1467, Dm Syx16, SYX16, Syx, dSyx 16" "IPR000727:Target SNARE coiled-coil homology domain, IPR006012:Syntaxin/epimorphin, conserved site, IPR010989:SNARE" CG1467 11-Aug-17 DroID_v2017_08 "Drer\stx12, Drer\stx16" "Scer\VAM3, Scer\TLG2, Scer\PEP12" "Cele\syx-16, Cele\syx-7" "Xtro\stx7, Xtro\stx16" "Mmus\Stx16, Mmus\Stx7, Mmus\Stx12" "Hsap\STX7, Hsap\STX16, Hsap\STX12" viable FBgn0065263 l(2)SH2079 lethal (2) SH2079 http://flybase.org/reports/FBgn0065263 gene - - - "l(2)SH2079, l(2)SH2 2079" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0019853 anon-VIII anon-VIII http://flybase.org/reports/FBgn0019853 - gene - - - "VIII, anon-VIII" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027344 fs(2)E9b fs(2)E9b http://flybase.org/reports/FBgn0027344 FBgn0000962 gene - - - "fs2.9, fs(2)E9, fs(2)E9b" - - 11-Aug-17 DroID_v2017_08 - - - - - - female fertile FBgn0040704 CG11930 - http://flybase.org/reports/FBgn0040704 protein_coding_gene - - - CG11930 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060878 l(3)S045507a lethal (3) S045507a http://flybase.org/reports/FBgn0060878 gene - - - "0455/07, l(3)S045507a" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0041135 l(2)44Fg lethal (2) 44Fg http://flybase.org/reports/FBgn0041135 gene - - - l(2)44Fg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0003281 rs rose http://flybase.org/reports/FBgn0003281 - gene - - - rs - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,visible,eye color defective,fertile,good,viable,heat sensitive" "Malpighian tubule,pigment cell,ocellus pigment granule" FBgn0038211 CG9649 - http://flybase.org/reports/FBgn0038211 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 endopeptidase activity ; GO:0004175 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 neurogenesis ; GO:0022008 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model" - "SP55, CG9649" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR031986:Serine protease gd, N-terminal domain" CG9649 11-Aug-17 DroID_v2017_08 "Drer\masp1, Drer\pamr1, Drer\f7" - Cele\try-5 Xtro\f10 Mmus\Prss48 Hsap\F7 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0283438 CG46280 - http://flybase.org/reports/FBgn0283438 protein_coding_gene - - - "CG46280, CG12360" "IPR002816:Pheromone shutdown, TraB" CG46280 11-Aug-17 DroID_v2017_08 "Drer\suv39h1a, Drer\suv39h1b, Drer\trabd, Drer\setmar" - "Cele\fbxa-171, Cele\set-23, Cele\set-25, Cele\F38A5.2, Cele\fbxa-167" "Xtro\suv39h2, Xtro\trabd" "Mmus\Setmar, Mmus\Suv39h1, Mmus\Trabd, Mmus\Suv39h2" "Hsap\SUV39H1, Hsap\LOC100506127, Hsap\TRABD, Hsap\SUV39H2" FBgn0259847 Su(Ste):CR42416 Su(Ste):CR42416 http://flybase.org/reports/FBgn0259847 non_protein_coding_gene - - - "Su(Ste):CR42416, CR42416" - CR42416 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003319 Sb Stubble http://flybase.org/reports/FBgn0003319 FBgn0010169 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model cytoskeleton organization ; GO:0007010 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "sbd, SP56, c-SP56, st-sb, Sb-sbd, CG4316, Sb" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG4316 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-238d18.3, Drer\tmprss4b, Drer\zgc:112038, Drer\zgc:92590, Drer\ctrl, Drer\try, Drer\tmprss9, Drer\zgc:112302, Drer\si:dkey-57c15.4, Drer\zgc:154142, Drer\zgc:153968, Drer\ela3l, Drer\prss60.2, Drer\zmp:0000001114, Drer\zgc:92511, Drer\zgc:123295, Drer\zgc:92041, Drer\zgc:163079, Drer\si:dkeyp-93a5.2, Drer\prss60.1, Drer\zgc:112285, Drer\mst1, Drer\ela2l, Drer\st14a, Drer\zgc:55888, Drer\zgc:112368, Drer\prss60.3, Drer\LOC562139, Drer\ctrb1, Drer\ela2, Drer\zgc:92745, Drer\zgc:112160, Drer\hgfa, Drer\zgc:171592" - "Cele\try-1, Cele\svh-1" "Xtro\ctrb1, Xtro\LOC100135144, Xtro\cela3a, Xtro\cela2a, Xtro\ctrb2" "Mmus\Gzmm, Mmus\Gm10334, Mmus\Cela3b, Mmus\Ctrl, Mmus\Ctrc, Mmus\Gzma, Mmus\Prss2, Mmus\Gm5771, Mmus\Try10, Mmus\Try4, Mmus\Ctrb1, Mmus\Tmprss13, Mmus\Prss1, Mmus\Cela2a, Mmus\Cela1, Mmus\Prss34, Mmus\Ovch2, Mmus\2210010C04Rik, Mmus\St14, Mmus\Prss3, Mmus\Cela3a" "Hsap\CTRB1, Hsap\CELA3B, Hsap\TMPRSS13, Hsap\CTRC, Hsap\ST14, Hsap\CELA2A, Hsap\OVCH2, Hsap\CELA2B, Hsap\CTRL, Hsap\PRSS3, Hsap\CTRB2, Hsap\CELA3A, Hsap\GZMA, Hsap\PRSS1, Hsap\CELA1, Hsap\GZMM" pupal stage " imaginal disc

, epidermis &&of leg | presumptive

, epidermis &&of wing | presumptive

" "visible,lethal,recessive,dominant,partially lethal - majority die,viable,poor,reduced,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,size defective" "chaeta,ventral thoracic disc,tibia,denticle belt,macrochaeta,ocellar bristle,metatarsus,leg,heat sensitive,adult thorax,dorsal,adult thorax & chaeta | conditional ts,prothoracic femur,microchaeta & actin filament,microchaeta & actin filamentsbd45),embryonic/first instar larval cuticle,anterior,wing vein L3,wing vein L4,anterior crossvein,wing,wing vein,ectopic,posterior crossvein" FBgn0034196 CG15605 - http://flybase.org/reports/FBgn0034196 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT23338, CG15605" "IPR006575:RWD domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG15605 11-Aug-17 DroID_v2017_08 "Drer\rwdd1, Drer\rwdd" Scer\GIR2 Cele\T26E3.4 "Xtro\rwdd4, Xtro\rwdd1" "Mmus\Rwdd4a, Mmus\Rwdd1" "Hsap\RWDD4, Hsap\RWDD1" viable FBgn0261907 Spc105R::Dwil\Spc105R - http://flybase.org/reports/FBgn0261907 engineered_fusion_gene - - - Spc105R::Dwil\Spc105R - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0045495 Gr28b Gustatory receptor 28b http://flybase.org/reports/FBgn0045495 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity taste receptor activity ; GO:0008527 | non-traceable author statement chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 melanization defense response ; GO:0035006 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity feeding behavior ; GO:0007631 | inferred from mutant phenotype sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 thermosensory behavior ; GO:0040040 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement negative phototaxis ; GO:0046957 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "CG13788, gr28b, Gr28b, Gr28bC, Gr28bE, Gr28bA, Gr28bD, Gr28bB, Gr28be, Gr28b.e, Gr28b.d, Gr28b.c, Gr28b.b, Gr28b.a, Gr28A3, GrLU2, Gr28A4, 28A3, LU.2, GRLU.2, GR28b, GR28B" IPR013604:7TM chemoreceptor CG13788 11-Aug-17 DroID_v2017_08 - - "Cele\gur-3, Cele\lite-1" - - - "temperature response defective,viable,fertile,feeding behavior defective,long lived,immune response defective,conditional,neurophysiology defective" FBgn0085595 CG41279 - http://flybase.org/reports/FBgn0085595 protein_coding_gene - - - CG41279 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031745 rau rau http://flybase.org/reports/FBgn0031745 protein_coding_gene Ras GTPase binding ; GO:0017016 | inferred from physical interaction with Ras85D protein homodimerization activity ; GO:0042803 | inferred from direct assay positive regulation of fibroblast growth factor receptor signaling pathway ; GO:0045743 | inferred from genetic interaction with pnt inferred from genetic interaction with sty positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | inferred from genetic interaction with pnt inferred from genetic interaction with sty R7 cell development ; GO:0045467 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype - "CG8965, rau" "IPR000159:Ras-associating (RA) domain, IPR029071:Ubiquitin-related domain" CG8965 11-Aug-17 DroID_v2017_08 - - Cele\W05B10.4 - - - "viable,fertile,male sterile" "eye,photoreceptor cell R7,embryonic/larval optic stalk surface glial cell,fascicle,photoreceptor cell R7 | third instar larval stage,supernumerary,fascicle | third instar larval stage" FBgn0051740 CG31740 - http://flybase.org/reports/FBgn0051740 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH22513, BcDNA:AT23551, CG31740" - CG31740 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265849 CR44638 - http://flybase.org/reports/FBgn0265849 non_protein_coding_gene - - - CR44638 - CR44638 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041139 l(2)44Dc lethal (2) 44Dc http://flybase.org/reports/FBgn0041139 gene - - - l(2)44Dc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260349 GSd314 - http://flybase.org/reports/FBgn0260349 gene - - - GSd314 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005754 l(1)TK309 lethal (1) TK309 http://flybase.org/reports/FBgn0005754 - gene - - - "l309, l(1)TK309" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0011134 l(1)Q209 lethal (1) Q209 http://flybase.org/reports/FBgn0011134 FBgn0010210 gene - - - l(1)Q209 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028667 Vha16-3 Vacuolar H[+] ATPase 16kD subunit 3 http://flybase.org/reports/FBgn0028667 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from sequence model" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR002379, InterPro:IPR011555 lysosomal lumen acidification ; GO:0007042 | inferred from biological aspect of ancestor with PANTHER:PTN000813819 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model" "integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000000753" "CG32090, vha16-3, CG7547, Vha16-3" "IPR000245:V-ATPase proteolipid subunit, IPR002379:V-ATPase proteolipid subunit C-like domain, IPR011555:V-ATPase proteolipid subunit C, eukaryotic" CG32090 11-Aug-17 DroID_v2017_08 "Drer\atp6v0cb, Drer\atp6v0ca" "Scer\VMA3, Scer\VMA11" "Cele\vha-3, Cele\vha-2, Cele\vha-1" Xtro\atp6v0c Mmus\Atp6v0c Hsap\ATP6V0C viable FBgn0050034 CG30034 - http://flybase.org/reports/FBgn0050034 protein_coding_gene - - - CG30034 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003426 slip slipshod http://flybase.org/reports/FBgn0003426 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available slip - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic segment" FBgn0040784 karr karr http://flybase.org/reports/FBgn0040784 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism development ; GO:0007275 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG15323, karr" - CG15323 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority live,male limited,some die during larval stage,male fertile" FBgn0016978 snRNP-U1-70K small ribonucleoprotein particle U1 subunit 70K http://flybase.org/reports/FBgn0016978 "FBgn0003458, FBgn0010508" protein_coding_gene mRNA binding ; GO:0003729 | inferred from direct assay U1 snRNA binding ; GO:0030619 | inferred from biological aspect of ancestor with PANTHER:PTN000359237 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1ZAK7 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:P08621 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with UniProtKB:P08621 oogenesis ; GO:0048477 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000001323 spermatogenesis ; GO:0007283 | inferred from mutant phenotype regulation of RNA splicing ; GO:0043484 | inferred from sequence or structural similarity with UniProtKB:P08621 negative regulation of mRNA splicing, via spliceosome ; GO:0048025 | inferred from physical interaction with Psi regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity with UniProtKB:P08621 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with UniProtKB:P08621 U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity with SGD:S000001323 nucleus ; GO:0005634 | inferred by curator from GO:0000381 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000359237 commitment complex ; GO:0000243 | inferred from biological aspect of ancestor with PANTHER:PTN000359236 precatalytic spliceosome ; GO:0071011 | inferred from direct assay U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000359237 "U1-70K, U1 snRNP, U170K, dU1-70K, Dm70K, CG8749, 70K, snRNP27D, U1 70K snRNP, snRNP, U1snRNP-70K, U1 70K, l(2)02107, snRNP70K, U1-70k, U1 70k, snRNP-U1-70K, U1, snRNP 70K" "IPR000504:RNA recognition motif domain, IPR034143:snRNP70, RNA recognition motif, IPR022023:U1 small nuclear ribonucleoprotein of 70kDa N-terminal" CG8749 11-Aug-17 DroID_v2017_08 "Drer\rbm24a, Drer\snrnp70, Drer\snrnp35" "Scer\TIF35, Scer\SNP1" "Cele\sup-12, Cele\rnp-7" "Xtro\snrnp70, Xtro\rbm24" "Mmus\Rbm24, Mmus\Snrnp70, Mmus\Snrnp35" "Hsap\RBM24, Hsap\SNRNP35, Hsap\SNRNP70" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0259536 GG01274 - http://flybase.org/reports/FBgn0259536 gene - - - GG01274 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,tarsal segment,unguis" FBgn0032228 CG5367 - http://flybase.org/reports/FBgn0032228 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 CG5367 "IPR025660:Cysteine peptidase, histidine active site, IPR000668:Peptidase C1A, papain C-terminal, IPR013128:Peptidase C1A, IPR013201:Cathepsin propeptide inhibitor domain (I29)" CG5367 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-269i1.4, Drer\cts12, Drer\LOC100333521, Drer\zgc:110239, Drer\si:dkey-239j18.2, Drer\MGC174857, Drer\ctsh, Drer\si:dkey-228a15.1, Drer\si:dkey-26g8.4, Drer\ctsl.1, Drer\wu:fa26c03, Drer\ctss1, Drer\ctsll, Drer\ctslb, Drer\si:dkey-239j18.3, Drer\LOC100536033, Drer\ctsba, Drer\ctsbb, Drer\ctss2.1, Drer\zgc:174153, Drer\si:dkey-183k8.2, Drer\si:dkey-269i1.3, Drer\ctsc, Drer\ctsk, Drer\ctss2.2, Drer\ctsz, Drer\MGC174155, Drer\ctso, Drer\si:dkey-267n13.1, Drer\zgc:174855, Drer\ctsla, Drer\zgc:103438" - "Cele\R09F10.1, Cele\K02E7.10, Cele\cpl-1" "Xtro\ctsc, Xtro\ctsl, Xtro\ctsw, Xtro\LOC100490139, Xtro\ctsv, Xtro\ctsh, Xtro\ctsb, Xtro\LOC100498238, Xtro\ctsz, Xtro\ctss" "Mmus\BC051665, Mmus\Ctsh, Mmus\Ctss, Mmus\Ctsw, Mmus\Ctla2a, Mmus\Ctsz, Mmus\Ctsr, Mmus\Ctso, Mmus\Ctsm, Mmus\Ctsj, Mmus\Cts7, Mmus\4930486L24Rik, Mmus\Ctsc, Mmus\Ctsk, Mmus\Ctsl, Mmus\Cts3, Mmus\Ctsll3, Mmus\Cts6, Mmus\Ctla2b, Mmus\Ctsb, Mmus\Ctsq, Mmus\Cts8" "Hsap\CTSB, Hsap\CTSZ, Hsap\CTSH, Hsap\CTSC, Hsap\CTSV, Hsap\CTSL, Hsap\CTSK, Hsap\CTSS, Hsap\CTSW, Hsap\CTSO" "lethal,recessive,viable" FBgn0261429 CR42646 - http://flybase.org/reports/FBgn0261429 non_protein_coding_gene - - - "CR42646, CR41445" - CR42646 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001586 l(1)carot3 lethal (1) carot3 http://flybase.org/reports/FBgn0001586 - gene - - - "l34, l(1)34, 34, l(1)carot3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262508 CG43078 - http://flybase.org/reports/FBgn0262508 protein_coding_gene - - - "CG43078, CG17926, CG32352, CG32353, CG6239, CG32355, lincRNA.473" - CG43078 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266744 CR45217 - http://flybase.org/reports/FBgn0266744 non_protein_coding_gene - - - CR45217 - CR45217 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003713 tkd thickoid http://flybase.org/reports/FBgn0003713 - gene - - - tkd - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority live,fertile,large body" "wing,leg,eye,male genitalia" FBgn0027589 CG1688 - http://flybase.org/reports/FBgn0027589 "FBgn0043917, FBgn0043919, FBgn0043920, FBgn0043921, FBgn0043954" protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" "BcDNA:GH04802, anon-WO0109301.50, anon-WO0109301.48, anon-WO0109301.47, anon-WO0109301.49, anon-WO0109301.12, CG1688" "IPR013099:Potassium channel domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR003280:Two pore domain potassium channel" CG1688 11-Aug-17 DroID_v2017_08 "Drer\kcnk5b, Drer\kcnk10a, Drer\kcnk18, Drer\kcnk1b, Drer\kcnk2a, Drer\kcnk10b, Drer\kcnk5a, Drer\kcnk7, Drer\kcnk6, Drer\kcnk1a" Scer\TOK1 "Cele\twk-48, Cele\twk-39, Cele\twk-10, Cele\twk-4, Cele\twk-3" "Xtro\kcnk2, Xtro\kcnk10, Xtro\kcnk4, Xtro\kcnk1, Xtro\kcnk6, Xtro\kcnk7, Xtro\kcnk16, Xtro\LOC100486031, Xtro\kcnk18, Xtro\kcnk5" "Mmus\Kcnk18, Mmus\Kcnk4, Mmus\Kcnk6, Mmus\Kcnk5, Mmus\Kcnk7, Mmus\Kcnk1, Mmus\Kcnk2, Mmus\Kcnk16, Mmus\Kcnk10" "Hsap\KCNK2, Hsap\KCNK5, Hsap\KCNK1, Hsap\KCNK7, Hsap\KCNK16, Hsap\KCNK17, Hsap\KCNK10, Hsap\KCNK4, Hsap\KCNK18, Hsap\KCNK6" "partially lethal - majority die,some die during pupal stage,viable" FBgn0065279 l(2)SH2041 lethal (2) SH2041 http://flybase.org/reports/FBgn0065279 gene - - - "l(2)SH2041, l(2)SH2 2041" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029131 Debcl Death executioner Bcl-2 http://flybase.org/reports/FBgn0029131 protein_coding_gene molecular_function ; GO:0003674 | no biological data available apoptotic process ; GO:0006915 | inferred from mutant phenotype autophagy ; GO:0006914 | NOT inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype apoptotic process involved in morphogenesis ; GO:0060561 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with UniProtKB:P10415 apoptotic process ; GO:0006915 | traceable author statement negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with Ank2 apoptotic process ; GO:0006915 | non-traceable author statement ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype positive regulation of macroautophagy ; GO:0016239 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from genetic interaction with Diap1 inferred from genetic interaction with Dark response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from sequence or structural similarity with HGNC:990 programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype regulation of programmed cell death ; GO:0043067 | inferred from genetic interaction with Dark intrinsic apoptotic signaling pathway in response to DNA damage ; GO:0008630 | inferred from mutant phenotype regulation of mitochondrial membrane permeability ; GO:0046902 | inferred from sequence or structural similarity with UniProtKB:P10415 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial envelope ; GO:0005740 | inferred from direct assay mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:P10415 "Debcl, debcl/Borg1, borg1/debcl, Drob-1/Debcl/dBorg-1/dBok, Bok(Debcl), Debcl/Drob-1/dBorg-1/dBok, Drob-1, Bok, dBOK, Debcl/dBorg-1/dRob-1, Dbok, dBorg01, CG12397, drob-1, debok, dBORG-1/DROB-1/DEBCL/dBOK, dBorg1, dBorg-1, DEBCL, Drob-1/Debcl/dBORG-1, Drob-1/Debcl/dBorg-1/DBok, DBok, dbok, BOK, BG1, dborg1, CG33134, debcl, Debcl/dBorg-1/dBok/Drob-1, debc1, dBok, dBrog-1, bcl-2, dbok/debcl, Bcl-2" "IPR002475:Bcl2-like, IPR026309:Bcl-2-related ovarian killer protein, IPR026298:Blc2 family" CG33134 11-Aug-17 DroID_v2017_08 "Drer\bcl2l1, Drer\boka, Drer\bcl2b, Drer\mcl1b, Drer\bokb, Drer\bcl2a, Drer\mcl1a" - Cele\ced-9 "Xtro\mcl1, Xtro\bok, Xtro\bcl2l1, Xtro\bcl2l2, Xtro\bcl2" "Mmus\Bcl2a1c, Mmus\Bcl2a1b, Mmus\Bcl2a1a, Mmus\Bcl2a1d, Mmus\Bcl2l1, Mmus\Bak1, Mmus\Bcl2, Mmus\Mcl1, Mmus\Bcl2l14, Mmus\Bok, Mmus\Pabpn1" "Hsap\BCL2A1, Hsap\BCL2L14, Hsap\BCL2L1, Hsap\BAK1, Hsap\BOK, Hsap\BCL2L2-PABPN1, Hsap\BCL2, Hsap\MCL1" " larval stage | third instar , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage | early , embryonic stage | stage 11 , embryonic stage | stage 14-16 , embryonic stage | stage 5 " " brain | resticted

, oocyte

, eye disc

, posterior midgut proper primordium

, ventral thoracic disc

, eye-antennal disc | resticted

, nurse cell

, dorsal mesothoracic disc

, embryonic/larval midgut

,

ubiquitous , proctodeum

, embryonic head segment | restricted

, embryonic/larval salivary gland duct

" "viable,fertile,radiation sensitive,decreased cell death,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,short lived,locomotor behavior defective,conditional,cell death defective,increased cell death,long lived,visible,neuroanatomy defective,somatic clone" "wing margin,conditional,scutellar bristle,supernumerary,male genitalia,vagina,maxillary palpus,tergite,sternite,melanotic mass,ventral nerve cord,Bolwig organ,midline glial cell,central nervous system,ectopic,eye,pigment cell,interommatidial bristle,eye photoreceptor cell,ommatidium,eye disc,posterior,wing,salivary gland,mitochondrion & dorsal multidendritic neuron ddaCppk.1.9,dendrite & dorsal multidendritic neuron ddaC | somatic cloneppk.1.9,dendrite & class IV dendritic arborising neuronppk.1.9,dendrite & abdominal anterior ventral multidendritic neuron vdaappk.1.9" FBgn0014342 mia meiosis I arrest http://flybase.org/reports/FBgn0014342 FBgn0037337 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from sequence or structural similarity with UniProtKB:P49848" regulation of sequence-specific DNA binding transcription factor activity ; GO:0051090 | inferred from electronic annotation with InterPro:IPR011442 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype spermatid development ; GO:0007286 | traceable author statement male meiosis I ; GO:0007141 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:17305 inferred from sequence or structural similarity with SGD:S000003080 meiotic nuclear division ; GO:0007126 | traceable author statement male germ cell nucleus ; GO:0001673 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:17305 inferred from sequence or structural similarity with SGD:S000003080 nucleolus ; GO:0005730 | inferred from direct assay "dTAF6L, dTAF[[II]]60, dmTAF6b, Taf6L, TAF, TFIID, Taf60-2, dTAF[[II]]60-2, TAF[[II]], TAF6L, CG10390, TAF60-2, ms(3)570, mia, TAF[[II]]60-2, Mia" "IPR011442:TAF6, C-terminal HEAT repeat domain, IPR009072:Histone-fold, IPR011989:Armadillo-like helical" CG10390 11-Aug-17 DroID_v2017_08 "Drer\taf6, Drer\taf6l" Scer\TAF6 "Cele\taf-6.2, Cele\taf-6.1" "Xtro\taf6, Xtro\taf6l" "Mmus\Taf6l, Mmus\Taf6" "Hsap\TAF6L, Hsap\TAF6" "viable,fertile,male sterile,recessive" "testis,spermatocyte" FBgn0060767 l(3)S062314 lethal (3) S062314 http://flybase.org/reports/FBgn0060767 gene - - - "0623/14, l(3)S062314" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0265143 CR44212 - http://flybase.org/reports/FBgn0265143 non_protein_coding_gene - - - CR44212 - CR44212 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0084049 CR41440 - http://flybase.org/reports/FBgn0084049 pseudogene_attribute - - - "CG40287, CR41440" - CR41440 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032240 CG17768 - http://flybase.org/reports/FBgn0032240 protein_coding_gene U6 snRNA binding ; GO:0017070 | inferred from biological aspect of ancestor with PANTHER:PTN000596817 U6 snRNA binding ; GO:0017070 | inferred from sequence or structural similarity with SGD:S000000914 "spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000596745 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000914 cytoplasmic mRNA processing body assembly ; GO:0033962 | inferred from biological aspect of ancestor with PANTHER:PTN000596817 nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from biological aspect of ancestor with PANTHER:PTN000596817 spliceosomal snRNP assembly ; GO:0000387 | inferred from biological aspect of ancestor with PANTHER:PTN000596745" spliceosomal tri-snRNP complex ; GO:0097526 | inferred from biological aspect of ancestor with PANTHER:PTN000596817 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000596817 U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from sequence or structural similarity with SGD:S000000914 U6 snRNP ; GO:0005688 | inferred from biological aspect of ancestor with PANTHER:PTN000596817 "CG31990, BcDNA:RE35747, CG5356, CG17768" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR027141:Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3, IPR034101:Sm-like protein Lsm4" CG17768 11-Aug-17 DroID_v2017_08 Drer\lsm4 Scer\LSM4 Cele\lsm-4 Xtro\lsm4 Mmus\Lsm4 Hsap\LSM4 DRSC02845 E -0.548537209 -0.021259324 -0.76578505 1.738559685 -0.873071949 0.149291831 FBgn0029994 CG2254 - http://flybase.org/reports/FBgn0029994 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay CG2254 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG2254 11-Aug-17 DroID_v2017_08 "Drer\sdr16c5b, Drer\rdh10b, Drer\si:dkey-221h15.4, Drer\rdh10a, Drer\sdr16c5a, Drer\rdh20, Drer\dhrs3b, Drer\dhrs3a" "Scer\TDA5, Scer\YDL114W" "Cele\dhs-4, Cele\dhs-19, Cele\dhs-3, Cele\dhs-29" "Xtro\rdh10, Xtro\sdr16c5, Xtro\hsd17b13, Xtro\dhrs3, Xtro\hsd17b11" "Mmus\Hsd17b13, Mmus\Rdh10, Mmus\Sdr16c5, Mmus\Sdr16c6, Mmus\Hsd17b11, Mmus\Dhrs3" "Hsap\HSD17B13, Hsap\HSD17B11, Hsap\SDR16C5, Hsap\RDH10, Hsap\DHRS3" viable FBgn0036039 Naa60 N(alpha)-acetyltransferase 60 http://flybase.org/reports/FBgn0036039 protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from direct assay chromosome segregation ; GO:0007059 | inferred from mutant phenotype N-terminal peptidyl-methionine acetylation ; GO:0017196 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred by curator from GO:0017196 "DmAAF50213, CG18177, Naa60, dNAA60, dNaa60, NatF, dNatF, Hat4, NAA60" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG18177 11-Aug-17 DroID_v2017_08 Drer\nat15 - "Cele\F54E7.9, Cele\F30F8.10" Xtro\naa60 Mmus\Naa60 Hsap\NAA60 viable FBgn0043041 l(2)42Ab lethal (2) 42Ab http://flybase.org/reports/FBgn0043041 gene - - - l(2)42Ab - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260004 Snmp1 Sensory neuron membrane protein 1 http://flybase.org/reports/FBgn0260004 protein_coding_gene - cellular response to pheromone ; GO:0071444 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from mutant phenotype response to pheromone ; GO:0019236 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 dendrite ; GO:0030425 | inferred from direct assay cilium ; GO:0005929 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "CG7000, Snmp1, SNMP, Snmp, snmp1, SNMP1, snmp" "IPR002159:CD36 family, IPR005428:CD36/scavenger receptor class B member 1" CG7000 11-Aug-17 DroID_v2017_08 "Drer\LOC564077, Drer\cd36, Drer\scarb2, Drer\scarb1" - "Cele\scav-4, Cele\scav-5, Cele\scav-3, Cele\scav-1, Cele\scav-6, Cele\scav-2" "Xtro\cd36, Xtro\scarb1, Xtro\scarb2" "Mmus\Cd36, Mmus\Scarb1, Mmus\Scarb2" "Hsap\SCARB2, Hsap\CD36, Hsap\SCARB1" FBgn0030058 CG11294 - http://flybase.org/reports/FBgn0030058 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CT31519, CG11294" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site" CG11294 11-Aug-17 DroID_v2017_08 "Drer\rx1, Drer\mxtx1, Drer\dharma, Drer\drgx" - "Cele\ceh-37, Cele\ceh-86, Cele\ceh-53" "Xtro\mixer, Xtro\bix1.1, Xtro\mix1" "Mmus\Rhox4d, Mmus\Rhox4f, Mmus\Rhox7a, Mmus\Rhox13, Mmus\Rhox3h, Mmus\Rhox3a2, Mmus\Rhox4b, Mmus\Isx, Mmus\Rhox11, Mmus\Rhox10, Mmus\Otx1, Mmus\Rhox4c, Mmus\Rhox3e, Mmus\Crx, Mmus\Rhox3f, Mmus\Otx2, Mmus\Rhox3a, Mmus\Esx1, Mmus\Prrxl1, Mmus\Rhox3c, Mmus\Rhox1, Mmus\Rhox3g, Mmus\Rhox4g, Mmus\Rhox4a2, Mmus\Rhox4e, Mmus\Rhox4a" "Hsap\RHOXF2, Hsap\RAX2, Hsap\ISX, Hsap\OTX1, Hsap\OTX2, Hsap\CRX, Hsap\DRGX, Hsap\RHOXF1, Hsap\ESX1, Hsap\RHOXF2B" lethal DRSC17777 K -0.411349728 -0.018532853 0.471724701 0.604063744 2.537995597 0.883912606 FBgn0037834 Art1 Arginine methyltransferase 1 http://flybase.org/reports/FBgn0037834 protein_coding_gene protein-arginine omega-N asymmetric methyltransferase activity ; GO:0035242 | inferred from direct assay protein-arginine omega-N monomethyltransferase activity ; GO:0035241 | inferred from direct assay histone methyltransferase activity (H4-R3 specific) ; GO:0044020 | inferred from direct assay histone methyltransferase activity ; GO:0042054 | inferred from direct assay "histone H4-R3 methylation ; GO:0043985 | inferred from direct assay histone methylation ; GO:0016571 | inferred from direct assay peptidyl-arginine methylation, to asymmetrical-dimethyl arginine ; GO:0019919 | inferred from direct assay" - "DART1, CG6554, Art1, Dart1, Dart, dart1" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR025799:Protein arginine N-methyltransferase" CG6554 11-Aug-17 DroID_v2017_08 "Drer\LOC556054, Drer\prmt6, Drer\prmt8b, Drer\prmt3, Drer\prmt1" Scer\HMT1 Cele\prmt-1 "Xtro\prmt1, Xtro\prmt8, Xtro\prmt3, Xtro\prmt6" "Mmus\Prmt8, Mmus\Prmt2, Mmus\Prmt1, Mmus\Prmt3, Mmus\Prmt6" "Hsap\PRMT8, Hsap\PRMT2, Hsap\PRMT3, Hsap\PRMT6, Hsap\PRMT1" "developmental rate defective,recessive,visible,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,viable,partially lethal" posterior crossvein FBgn0263877 D76 - http://flybase.org/reports/FBgn0263877 gene - - - D76 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell number,somatic clone" "embryonic/larval neuroblast,somatic clone,embryonic/larval brain" FBgn0044872 FucTC FucTC http://flybase.org/reports/FBgn0044872 protein_coding_gene alpha-(1->3)-fucosyltransferase activity ; GO:0046920 | inferred from biological aspect of ancestor with PANTHER:PTN000231531 fucosyltransferase activity ; GO:0008417 | inferred from sequence or structural similarity with HGNC:4017 protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR001503 Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000231531 "CG40305, FucTC" "IPR001503:Glycosyl transferase family 10, IPR031481:Fucosyltransferase, N-terminal" CG40305 11-Aug-17 DroID_v2017_08 "Drer\fut7, Drer\zgc:112433, Drer\zgc:165582, Drer\fut11, Drer\fut9a, Drer\zgc:173737, Drer\ft1, Drer\zgc:165519, Drer\ft2, Drer\fut10, Drer\fut9b, Drer\zgc:103510, Drer\fut9d, Drer\si:ch1073-440p11.2, Drer\zgc:136963, Drer\ctu1" - "Cele\fut-5, Cele\C07E3.8, Cele\fut-6, Cele\fut-3, Cele\fut-1, Cele\fut-4" "Xtro\fut10, Xtro\fut11, Xtro\fut3, Xtro\fut4, Xtro\fut6, Xtro\fut9" "Mmus\Fut9, Mmus\Fut7, Mmus\Fut10, Mmus\Fut11, Mmus\Fut4" "Hsap\FUT11, Hsap\FUT5, Hsap\FUT9, Hsap\FUT3, Hsap\FUT4, Hsap\FUT10, Hsap\FUT7, Hsap\FUT6" FBgn0052861 snRNA:U4atac:83A snRNA:U4atac:83A http://flybase.org/reports/FBgn0052861 snRNA_gene - - - "CR32861, snRNA:U4atac:83A" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037015 cmpy crimpy http://flybase.org/reports/FBgn0037015 protein_coding_gene "insulin-like growth factor binding ; GO:0005520 | inferred from electronic annotation with InterPro:IPR000867, InterPro:IPR011390 protein binding ; GO:0005515 | inferred from physical interaction with gbb BMP binding ; GO:0036122 | inferred from genetic interaction with gbb" "regulation of cell growth ; GO:0001558 | inferred from electronic annotation with InterPro:IPR000867, InterPro:IPR011390 regulation of BMP secretion ; GO:2001284 | inferred from mutant phenotype negative regulation of BMP signaling pathway by negative regulation of BMP secretion ; GO:0038056 | inferred from physical interaction with gbb neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype negative regulation of BMP signaling pathway ; GO:0030514 | inferred from genetic interaction with Mad inferred from genetic interaction with wit inferred from genetic interaction with gbb synaptic vesicle cycle ; GO:0099504 | inferred from mutant phenotype" "extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR000867, InterPro:IPR011390 dense core granule ; GO:0031045 | inferred from direct assay type III terminal bouton ; GO:0097467 | inferred from direct assay" "cmpy, CG13253, Cmpy" "IPR011390:Insulin-like growth factor binding protein-related protein (IGFBP-rP), MAC25, IPR009030:Growth factor receptor cysteine-rich domain, IPR000867:Insulin-like growth factor-binding protein, IGFBP" CG13253 11-Aug-17 DroID_v2017_08 Drer\si:ch73-330k17.3 - - - - Hsap\ESM1 "viable,female sterile,recessive,neuroanatomy defective" "type I bouton,supernumerary,supernumerary | third instar larval stage,type I bouton | third instar larval stage" FBgn0038756 CG4783 - http://flybase.org/reports/FBgn0038756 protein_coding_gene - - - "GH26202, CG4783" - CG4783 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0046628 anon-AE003550.1 anon-AE003550.1 http://flybase.org/reports/FBgn0046628 gene - - - anon-AE003550.1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060578 l(3)S095204b lethal (3) S095204b http://flybase.org/reports/FBgn0060578 gene - - - "0952/04, l(3)S095204b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0063908 Neurodegeneration-11 Neurodegeneration 11 http://flybase.org/reports/FBgn0063908 gene - - - "ND11, Neurodegeneration-11" - - 11-Aug-17 DroID_v2017_08 - - - - - - central nervous system FBgn0037153 olf413 olf413 http://flybase.org/reports/FBgn0037153 protein_coding_gene dopamine beta-monooxygenase activity ; GO:0004500 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN001605435 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000323, InterPro:IPR000945, InterPro:IPR014784 dopamine catabolic process ; GO:0042420 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 norepinephrine biosynthetic process ; GO:0042421 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 octopamine biosynthetic process ; GO:0006589 | inferred from biological aspect of ancestor with PANTHER:PTN000806665" secretory granule membrane ; GO:0030667 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 cytosol ; GO:0005829 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CG7495, CG14461, CR33185, CG12673, olf413, Olf413" "IPR000323:Copper type II, ascorbate-dependent monooxygenase, N-terminal, IPR000945:Dopamine beta-hydroxylase-related, IPR005018:DOMON domain, IPR008977:PHM/PNGase F domain, IPR014784:Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, IPR024548:Copper type II ascorbate-dependent monooxygenase, C-terminal" CG12673 11-Aug-17 DroID_v2017_08 "Drer\moxd1l, Drer\moxd1, Drer\dbh" - Cele\tbh-1 "Xtro\dbh, Xtro\moxd1" "Mmus\Moxd1, Mmus\Moxd2, Mmus\Dbh" "Hsap\MOXD1, Hsap\DBH" DRSC11833 EK -0.70812888 -0.193917478 1.990539255 0.209447807 2.0015963 0.41620867 FBgn0035285 CG12025 - http://flybase.org/reports/FBgn0035285 protein_coding_gene - - - CG12025 "IPR008590:Protein of unknown function DUF872, transmembrane, IPR023271:Aquaporin-like" CG12025 11-Aug-17 DroID_v2017_08 "Drer\tmem134, Drer\tmem230a, Drer\tmem230b" - Cele\F21F3.7 Xtro\tmem230 "Mmus\Tmem230, Mmus\Tmem134" "Hsap\TMEM230, Hsap\TMEM134" viable DRSC08230 K -0.329521731 0.54658605 0.29287442 0.923480631 -1.025185482 1.601113619 FBgn0036610 CG13058 - http://flybase.org/reports/FBgn0036610 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13058 - CG13058 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC27898 K 0.506108483 0.295712528 -0.190027776 -0.021719054 0.399866532 1.67877551 FBgn0053436 5SrRNA:CR33436 5SrRNA:CR33436 http://flybase.org/reports/FBgn0053436 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33436, 5SrRNA:CR33436" - CR33436 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264464 CR43872 - http://flybase.org/reports/FBgn0264464 non_protein_coding_gene - - - "CG43872, CR43872" - CR43872 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039312 CG10514 - http://flybase.org/reports/FBgn0039312 protein_coding_gene - - - "CT29508, CG10514" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG10514 11-Aug-17 DroID_v2017_08 - - "Cele\H37A05.2, Cele\C18B10.6, Cele\F58B4.5, Cele\E02C12.10, Cele\nhr-246, Cele\E02C12.6, Cele\H06H21.8, Cele\E02C12.8, Cele\F56A4.5, Cele\E02C12.9, Cele\Y45G12C.4, Cele\F20D6.5" - - - viable FBgn0005111 l(1)3C3 lethal (1) 3C3 http://flybase.org/reports/FBgn0005111 - gene - - - l(1)3C3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000100 RpLP0 Ribosomal protein LP0 http://flybase.org/reports/FBgn0000100 FBgn0010752 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "ribosome biogenesis ; GO:0042254 | inferred from electronic annotation with InterPro:IPR001790, InterPro:IPR030670 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement" cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "RpP0, RpPO, AP3, P35, PO, P0, l(3)0154, Ape, RLA0, l(3)01544, CG7490, Ap3, RpLP0, LP0, p0, RPL P0, Rplp0" "IPR001790:Ribosomal protein L10P, IPR030670:60S acidic ribosomal protein P0" CG7490 11-Aug-17 DroID_v2017_08 Drer\rplp0 Scer\RPP0 Cele\rla-0 Xtro\rplp0 Mmus\Rplp0 Hsap\RPLP0 "lethal,recessive,suppressor of variegation,dominant,non-suppressor of variegation,wild-type" DRSC22110 IEK -0.366955874 -1.517568525 2.914994774 -3.874587585 2.093225315 4.288150414 FBgn0000279 CecC Cecropin C http://flybase.org/reports/FBgn0000279 FBgn0062945 protein_coding_gene - defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern humoral immune response ; GO:0006959 | inferred from expression pattern defense response to bacterium ; GO:0042742 | traceable author statement antibacterial humoral response ; GO:0019731 | inferred from direct assay defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CecC, Cec, CG1373, cecC, Cec-C, cec, BcDNA:RH33561" "IPR020400:Cecropin, diptera, IPR000875:Cecropin" CG1373 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001335 l(1)1Ad lethal (1) 1Ad http://flybase.org/reports/FBgn0001335 - gene - - - "lEC2, EC2, l[EC2], l(1)2804, l(1)EC2, l(1)1Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" FBgn0010214 Prl Proxless http://flybase.org/reports/FBgn0010214 - gene - - - Prl - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "costal cell,wing vein L2,wing vein L5,wing vein L6,alula,anterior crossvein,posterior crossvein" FBgn0011852 tRNA:Glu-CTC-3-5 transfer RNA:Glutamic acid-CTC 3-5 http://flybase.org/reports/FBgn0011852 "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052326, FBgn0060249" tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "AE002584.trna7-GluCTC, tRNA:E4, tRNA:E:CTC:AE002584-e, tRNA:glu4:62Ab, CR32326, tRNA:Glu, chr3L.trna7-GluCTC, tRNA:Glu-CTC-3-5, tRNA:E4:62Ab, tRNA-Glu-CTC-3-5, GAG" - CR32326 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010125 l(1)M1 lethal (1) M1 http://flybase.org/reports/FBgn0010125 - gene - - - l(1)M1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0010147 l(3)96Fe lethal (3) 96Fe http://flybase.org/reports/FBgn0010147 - gene - - - "l(3)B128, l(3)96Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032632 CG6380 - http://flybase.org/reports/FBgn0032632 protein_coding_gene protein phosphatase inhibitor activity ; GO:0004864 | inferred from biological aspect of ancestor with PANTHER:PTN000273866 regulation of signal transduction ; GO:0009966 | inferred from electronic annotation with InterPro:IPR007062 regulation of phosphoprotein phosphatase activity ; GO:0043666 | inferred from biological aspect of ancestor with PANTHER:PTN000273866 protein phosphatase type 1 complex ; GO:0000164 | inferred from biological aspect of ancestor with PANTHER:PTN000273866 CG6380 IPR007062:Protein phosphatase inhibitor 2 (IPP-2) CG6380 11-Aug-17 DroID_v2017_08 Drer\ppp1r2 Scer\GLC8 Cele\szy-2 - "Mmus\2810408A11Rik, Mmus\Ppp1r2" Hsap\PPP1R2 viable FBgn0266182 CR44888 - http://flybase.org/reports/FBgn0266182 non_protein_coding_gene - - - CR44888 - CR44888 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266115 CR44841 - http://flybase.org/reports/FBgn0266115 non_protein_coding_gene - - - CR44841 - CR44841 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040376 CG13759 - http://flybase.org/reports/FBgn0040376 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 "CT33239, EG:BACR25B3.5, BcDNA:AT19803, CG13759, AANATL7" IPR016181:Acyl-CoA N-acyltransferase CG13759 11-Aug-17 DroID_v2017_08 - - "Cele\R05H10.1, Cele\anat-1, Cele\M7.8, Cele\W02D7.4, Cele\T10B5.4, Cele\R13D11.4, Cele\F36D3.8, Cele\M7.12, Cele\R05H10.7, Cele\C28D4.4, Cele\C28D4.7, Cele\T09F5.10, Cele\C28D4.5, Cele\W02D7.5, Cele\F10G2.7" - - - FBgn0025613 CG3081 - http://flybase.org/reports/FBgn0025613 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "EG:84H4.4, CG3081" IPR032084:Domain of unknown function DUF4812 CG3081 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035792 CG7548 - http://flybase.org/reports/FBgn0035792 protein_coding_gene - - - CG7548 IPR022727:Pupal cuticle protein C1 CG7548 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC29043 K 0.377572115 0.706384869 0.503823625 0.038220683 -0.852142161 -4.992974036 FBgn0038926 CG13409 - http://flybase.org/reports/FBgn0038926 protein_coding_gene toxic substance binding ; GO:0015643 | inferred from sequence or structural similarity with HGNC:20958 pathogenesis ; GO:0009405 | inferred from sequence or structural similarity with HGNC:20958 cellular_component ; GO:0005575 | no biological data available CG13409 - CG13409 11-Aug-17 DroID_v2017_08 Drer\tmem181 - - Xtro\tmem181 Mmus\Tmem181a Hsap\TMEM181 viable FBgn0012010 tRNA:Val-AAC-2-3 transfer RNA:Valine-AAC 2-3 http://flybase.org/reports/FBgn0012010 "FBgn0003858, FBgn0012007, FBgn0052124, FBgn0060031" tRNA_gene GUU codon-amino acid adaptor activity ; GO:0033449 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033449 cytosol ; GO:0005829 | inferred by curator from GO:0033449 "valine tRNA, val-tRNA-4, tRNA-Val-4, tRNA[Val][[4]], AE002602.trna22-ValAAC, tRNA:V4, tRNA:V:AAC:AE002602-b, CR32124, tRNA:val4:70BCb, tRNA[Val-AAC], chr3L.trna27-ValAAC, tRNA:Val-AAC-2-3, tRNA:V4:70BCb, tRNA-Val-AAC-2-3, GUU" - CR32124 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030372 CG12722 - http://flybase.org/reports/FBgn0030372 protein_coding_gene - - - CG12722 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065695 l(2)SH0637 lethal (2) SH0637 http://flybase.org/reports/FBgn0065695 gene - - - "l(2)SH0637, l(2)SH2 0637" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033303 Cyp6a15Psi Cyp6a15Psi http://flybase.org/reports/FBgn0033303 pseudogene_attribute - - - "6a15p, Cyp6a15p, CG14753, CR14753, Cyp6a15Psi" - CR14753 11-Aug-17 DroID_v2017_08 - - - - - - DRSC07377 E -0.515407516 0.18445392 0.340902742 2.080053596 0.144111646 1.39981789 FBgn0039184 CG6432 - http://flybase.org/reports/FBgn0039184 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG6432 "IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase, IPR032387:Acetyl-coenzyme A synthetase, N-terminal domain" CG6432 11-Aug-17 DroID_v2017_08 "Drer\acss3, Drer\aacs, Drer\acss1, Drer\acss2, Drer\acsm3" "Scer\ACS1, Scer\ACS2" "Cele\sur-5, Cele\acs-19, Cele\acs-9" "Xtro\acss2.2, Xtro\acss1, Xtro\acss3, Xtro\acsm3, Xtro\aacs, Xtro\acss2.1" "Mmus\Acss2, Mmus\Acss1, Mmus\Aacs, Mmus\Acsm2, Mmus\Acsm1, Mmus\Acsm5, Mmus\Acsm3, Mmus\Acss3, Mmus\Acsm4" "Hsap\ACSS3, Hsap\ACSM2B, Hsap\ACSM5, Hsap\ACSM3, Hsap\ACSM4, Hsap\ACSS2, Hsap\ACSM1, Hsap\ACSS1, Hsap\ACSM2A, Hsap\ACSM6, Hsap\AACS" viable FBgn0030053 CG12081 - http://flybase.org/reports/FBgn0030053 protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with HGNC:20704 biological_process ; GO:0008150 | no biological data available nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with HGNC:20704 CG12081 "IPR006652:Kelch repeat type 1, IPR011043:Galactose oxidase/kelch, beta-propeller, IPR015915:Kelch-type beta propeller" CG12081 11-Aug-17 DroID_v2017_08 "Drer\zgc:163014, Drer\si:dkey-3d4.3, Drer\klhdc10, Drer\klhdc3, Drer\rabepk, Drer\zmp:0000001301, Drer\hcfc1a, Drer\hcfc1b, Drer\krcp, Drer\klhdc4" "Scer\KEL2, Scer\KEL3, Scer\KEL1" "Cele\hcf-1, Cele\F53E4.1, Cele\Y50D7A.1" "Xtro\klhdc9, Xtro\klhdc10, Xtro\fbxo42, Xtro\klhdc3, Xtro\rabepk, Xtro\klhdc1, Xtro\klhdc2" "Mmus\Fbxo42, Mmus\Klhdc3, Mmus\Hcfc2, Mmus\Klhdc2, Mmus\Hcfc1, Mmus\Rabepk, Mmus\Klhdc10, Mmus\Klhdc9, Mmus\Klhdc1, Mmus\Klhdc4, Mmus\Lztr1" "Hsap\KLHDC9, Hsap\RABEPK, Hsap\KLHDC1, Hsap\FBXO42, Hsap\KLHDC2, Hsap\HCFC1, Hsap\KLHDC3, Hsap\HCFC2, Hsap\KLHDC4, Hsap\KLHDC10, Hsap\LZTR1" viable FBgn0024840 rK(2)639 rK(2)639 http://flybase.org/reports/FBgn0024840 - gene - - - rK(2)639 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0058224 CG40224 - http://flybase.org/reports/FBgn0058224 protein_coding_gene - - - CG40224 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001043 fs(3)HO29 female sterile (3) HO29 http://flybase.org/reports/FBgn0001043 - gene - - - "fs(3)29A, fs(3)HO29" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "oocyte,ovary" FBgn0266854 CR45315 - http://flybase.org/reports/FBgn0266854 pseudogene_attribute - - - CR45315 - CR45315 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003607 Su(var)205 Suppressor of variegation 205 http://flybase.org/reports/FBgn0003607 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with ADD1 inferred from physical interaction with HIPP1 rDNA binding ; GO:0000182 | inferred from direct assay methylated histone binding ; GO:0035064 | traceable author statement chromatin binding ; GO:0003682 | inferred from direct assay RNA binding ; GO:0003723 | inferred from direct assay histone binding ; GO:0042393 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95RV2 mRNA binding ; GO:0003729 | non-traceable author statement satellite DNA binding ; GO:0003696 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Su(var)3-7 "telomere maintenance ; GO:0000723 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype regulation of histone methylation ; GO:0031060 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from direct assay inferred from mutant phenotype histone H4-K20 trimethylation ; GO:0034773 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from direct assay DNA hypermethylation ; GO:0044026 | inferred from mutant phenotype positive regulation of histone H3-K9 dimethylation ; GO:1900111 | inferred from direct assay inferred from mutant phenotype heterochromatin assembly ; GO:0031507 | inferred from direct assay regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement positive regulation of methylation-dependent chromatin silencing ; GO:0090309 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype establishment of chromatin silencing ; GO:0006343 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement positive regulation of extent of heterochromatin assembly ; GO:0033697 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype" "polytene chromosome chromocenter ; GO:0005701 | traceable author statement polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay pericentric heterochromatin ; GO:0005721 | inferred from direct assay chromosome, telomeric region ; GO:0000781 | inferred from direct assay heterochromatin ; GO:0000792 | traceable author statement euchromatin ; GO:0000791 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay condensed chromosome ; GO:0000793 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay heterochromatin ; GO:0000792 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | traceable author statement polytene chromosome, telomeric region ; GO:0035012 | traceable author statement chromosome, centromeric region ; GO:0000775 | traceable author statement polytene chromosome ; GO:0005700 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay nuclear heterochromatin ; GO:0005720 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | non-traceable author statement" "Su(var)2-5, HP1, Su(var)205, HP1A, HP-1, HP1a, Hp1, DmHP1, Su(var)[205], HP1alpha, DmHP-1, Su(var), HP1-VS, dHP1, su(var)205, Su(Var)2-5, Su(var)2-05, Su(var)2-501, Suvar(2)5, Suvar2-5, Su-var(2)5, E(var)29, Su(var)29A, E(var)29A, CG8409, Su[Var]205, SU(VAR)205, Su[var]205, Hp1a, dHP-1a, hp1a, hp1, FBgn0003607, CBX5, Su(Var)205" "IPR017984:Chromo domain subgroup, IPR000953:Chromo/chromo shadow domain, IPR008251:Chromo shadow domain, IPR016197:Chromo domain-like, IPR023779:Chromo domain, conserved site, IPR023780:Chromo domain" CG8409 11-Aug-17 DroID_v2017_08 "Drer\cdyl, Drer\cbx1a, Drer\cbx1b, Drer\cbx5, Drer\cbx3b, Drer\cbx3a" Scer\NEW1 "Cele\set-31, Cele\hpl-2, Cele\H04D03.6, Cele\hpl-1" "Xtro\cbx3, Xtro\cbx5, Xtro\cbx1" "Mmus\Cdyl2, Mmus\Cbx5, Mmus\Cdyl, Mmus\Cbx3, Mmus\Mphosph8, Mmus\Cbx7, Mmus\Cbx1" "Hsap\CDY1B, Hsap\CDY2A, Hsap\CBX7, Hsap\CDY2B, Hsap\CBX3, Hsap\CDYL, Hsap\MPHOSPH8, Hsap\CBX5, Hsap\CDY1, Hsap\CDYL2, Hsap\CBX1" adult stage larval stage larval salivary gland

"lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,wild-type,non-enhancer of variegation,suppressor of variegation,recessive,dominant,non-suppressor of variegation,lethal,increased cell death,neuroanatomy defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable,female sterile" "wing,posterior,wing disc,eye disc,eye,neuroblast,neuroblast & larval brain,polytene chromosome2055),chromosome, telomeric region2055),mitosis & nuclear chromosome2055),imaginal disc,polytene chromosome | male2055),meiosis & nuclear chromosome | male,chromosome, telomeric region,melanotic mass,mitosis & chromosome, telomeric region,prothoracic gland,gastric caecum,embryonic/larval optic lobe,chromosome, telomeric region2054),mitosis & nuclear chromosome2054),polytene chromosome2054),polytene chromosome | male2054),polytene chromosome20503),mitotic cell cycle, with Su(var)205a.cDLa,mitotic cell cycle, with Su(var)205cDLa,polytene chromosome,embryonic/larval neuroblast,ganglion mother cell" FBgn0001765 l(1)M25 lethal (1) M25 http://flybase.org/reports/FBgn0001765 - gene - - - l(1)M25 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0021920 l(2)k11303 lethal (2) k11303 http://flybase.org/reports/FBgn0021920 - gene - - - l(2)k11303 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0032130 CG3838 - http://flybase.org/reports/FBgn0032130 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - - "bs09e08.y1, NEST:bs09e08, anon-WO0118547.445, CG3838, CC20" "IPR004210:BESS motif, IPR006578:MADF domain" CG3838 11-Aug-17 DroID_v2017_08 "Drer\zgc:152938, Drer\si:ch211-207i20.3, Drer\LOC100330838" - "Cele\madf-4, Cele\madf-10, Cele\madf-2, Cele\madf-3, Cele\madf-8, Cele\madf-5, Cele\madf-9" - - - viable FBgn0035591 CG4611 - http://flybase.org/reports/FBgn0035591 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000755749 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:22198 endonuclease activity ; GO:0004519 | inferred from biological aspect of ancestor with PANTHER:PTN000755749 RNA modification ; GO:0009451 | inferred from biological aspect of ancestor with PANTHER:PTN000755749 tRNA 3'-end processing ; GO:0042780 | inferred from sequence or structural similarity with HGNC:22198 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN002368406 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:22198 CG4611 "IPR002885:Pentatricopeptide repeat, IPR033443:Pentacotripeptide-repeat region of PROPR" CG4611 11-Aug-17 DroID_v2017_08 Drer\ptcd1 "Scer\PET309, Scer\MRX1" - Xtro\ptcd1 Mmus\Ptcd1 "Hsap\ATP5J2-PTCD1, Hsap\ATP5J2, Hsap\PTCD1" "viable,visible" trichogen cell FBgn0266201 CR44896 - http://flybase.org/reports/FBgn0266201 non_protein_coding_gene - - - CR44896 - CR44896 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067784 arr::fz2 arr::fz2 http://flybase.org/reports/FBgn0067784 engineered_fusion_gene - - - arr::fz2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing vein,ectopic,wing margin bristle,denticle row 3,denticle row 4,denticle row 5,denticle row 6" FBgn0267881 CR46169 - http://flybase.org/reports/FBgn0267881 pseudogene_attribute - - - CR46169 - CR46169 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031313 CG5080 - http://flybase.org/reports/FBgn0031313 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available plasma membrane ; GO:0005886 | inferred from direct assay "CT16297, CG5080" - CG5080 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065860 l(2)SH0277 lethal (2) SH0277 http://flybase.org/reports/FBgn0065860 gene - - - "l(2)SH0277, l(2)SH2 0277" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014279 oho51 overgrown hematopoietic organs 51 http://flybase.org/reports/FBgn0014279 FBgn0016987 gene molecular_function ; GO:0003674 | no biological data available lymph gland development ; GO:0048542 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)211/5, l(2)211/15, l(2)k21105, oho51" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval brain,embryonic/larval lymph gland" FBgn0061102 l(3)S008806b lethal (3) S008806b http://flybase.org/reports/FBgn0061102 gene - - - "0088/06, l(3)S008806b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024755 EP2585 EP2585 http://flybase.org/reports/FBgn0024755 - gene - - - EP2585 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0066374 arl arleekin http://flybase.org/reports/FBgn0066374 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available arl - - 11-Aug-17 DroID_v2017_08 - - - - - - memory defective FBgn0044353 Quasimodo\gag Quasimodo element gag http://flybase.org/reports/FBgn0044353 transposable_element_gene - - - "cruiser\gag, Quasimodo\gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039219 CG13630 - http://flybase.org/reports/FBgn0039219 protein_coding_gene aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR002467 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR002467 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR002467 - "MAP1A, CG13630" "IPR000994:Peptidase M24, IPR001714:Peptidase M24, methionine aminopeptidase, IPR002467:Peptidase M24A, methionine aminopeptidase, subfamily 1, IPR031615:MYND-like zinc finger, mRNA-binding" CG13630 11-Aug-17 DroID_v2017_08 "Drer\metap1d, Drer\metap1" Scer\MAP1 Cele\map-1 "Xtro\metap1d, Xtro\metap1" "Mmus\Metap1d, Mmus\Metap1" "Hsap\METAP1D, Hsap\METAP1" FBgn0002498 l(3)SG59 lethal (3) SG59 http://flybase.org/reports/FBgn0002498 - gene - - - l(3)SG59 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0263541 mir-4986 mir-4986 stem loop http://flybase.org/reports/FBgn0263541 miRNA_gene - - - "mir-4986, dme-mir-4986, CR43526" - CR43526 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260749 Utx Utx histone demethylase http://flybase.org/reports/FBgn0260749 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR029516 protein binding ; GO:0005515 | inferred from physical interaction with EcR inferred from physical interaction with usp core promoter binding ; GO:0001047 | inferred from direct assay histone demethylase activity ; GO:0032452 | inferred from direct assay histone demethylase activity (H3-K27 specific) ; GO:0071558 | inferred from direct assay "wound healing ; GO:0042060 | inferred from mutant phenotype negative regulation of histone H3-K27 trimethylation ; GO:1902465 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from direct assay induction of programmed cell death by ecdysone ; GO:0035078 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter in response to DNA damage ; GO:1990248 | inferred from mutant phenotype negative regulation of histone H3-K27 methylation ; GO:0061086 | inferred from mutant phenotype histone demethylation ; GO:0016577 | inferred from direct assay histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with Dl inferred from genetic interaction with Ser inferred from genetic interaction with N histone H3-K27 demethylation ; GO:0071557 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype sex comb development ; GO:0045498 | inferred from mutant phenotype ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype" transcriptionally active chromatin ; GO:0035327 | colocalizes_with inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay MLL3/4 complex ; GO:0044666 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay "UTX, CG5640, dUTX, anon-31BCa, Utx, dUtx, utx" "IPR003347:JmjC domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR029516:Histone demethylase UTY" CG5640 11-Aug-17 DroID_v2017_08 "Drer\kdm6ba, Drer\ifit8, Drer\kdm6bb, Drer\ogt.2, Drer\ttc6, Drer\ifit14, Drer\ogt.1, Drer\ifit9, Drer\ttc25, Drer\bbs4, Drer\kdm5c, Drer\ifit15, Drer\jarid2b, Drer\dyx1c1, Drer\tomm34, Drer\ifit16, Drer\spag1a, Drer\kdm5bb, Drer\kdm5ba, Drer\tmtc3, Drer\spag1b, Drer\kdm6a, Drer\fkbpl, Drer\kdm6al" "Scer\TAH1, Scer\JHD2, Scer\ECM5, Scer\SWA2, Scer\CYC8" "Cele\jmjd-3.2, Cele\jmjd-3.3, Cele\jmjd-3.1, Cele\utx-1" "Xtro\ttc25, Xtro\kdm5a, Xtro\bbs4, Xtro\ogt, Xtro\kdm5c, Xtro\dyx1c1, Xtro\ttc16, Xtro\ifit5, Xtro\kdm6a, Xtro\tmtc3, Xtro\kdm6b, Xtro\kdm5b, Xtro\spag1" "Mmus\Ifit3, Mmus\Kdm5c, Mmus\Ifit1, Mmus\Ifit2, Mmus\Kdm6b, Mmus\Fkbpl, Mmus\Ttc25, Mmus\Kdm5d, Mmus\Kdm6a, Mmus\Uty, Mmus\Ogt, Mmus\Kdm5a, Mmus\Tomm34, Mmus\Kdm5b, Mmus\Ifit1bl2, Mmus\Ifit3b, Mmus\Ttc16, Mmus\Ttc24, Mmus\Lonrf3, Mmus\Spag1, Mmus\Dyx1c1, Mmus\Bbs4, Mmus\Ifit1bl1, Mmus\Tmtc3, Mmus\Tmtc1" "Hsap\TTC32, Hsap\UTY, Hsap\TMTC3, Hsap\IFIT1B, Hsap\KDM5D, Hsap\IFIT1, Hsap\TMTC1, Hsap\TOMM34, Hsap\TTC16, Hsap\BBS4, Hsap\FKBPL, Hsap\OGT, Hsap\DYX1C1, Hsap\LONRF3, Hsap\IFIT3, Hsap\KDM6B, Hsap\IFIT5, Hsap\KDM5B, Hsap\LONRF2, Hsap\TTC24, Hsap\IFIT2, Hsap\KDM5A, Hsap\KDM5C, Hsap\TTC6, Hsap\SPAG1, Hsap\KDM6A" DRSC02872 I 0.98005238 1.6028577 0.172204273 1.073779263 0.070810418 0.419056625 FBgn0028634 ifm(2)RU8 indirect flight muscle (2) RU8 http://flybase.org/reports/FBgn0028634 gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay ifm(2)RU8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,flight defective,viable" "wing,dorsal medial muscle,indirect flight muscle & myofibril" FBgn0067768 grl gerlache http://flybase.org/reports/FBgn0067768 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available grl - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "egg chamber,germline clone,egg" FBgn0017393 l(1)10Bt lethal (1) 10Bt http://flybase.org/reports/FBgn0017393 - gene - - - "HM416, l(1)10Bt" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029828 CG6067 - http://flybase.org/reports/FBgn0029828 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - CG6067 "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG6067 11-Aug-17 DroID_v2017_08 - - - Xtro\gzmh - - viable FBgn0039498 CG17991 - http://flybase.org/reports/FBgn0039498 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:26025 zinc ion binding ; GO:0008270 | inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:26025 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with HGNC:26025 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with HGNC:26025 CG17991 "IPR011016:Zinc finger, RING-CH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033275:E3 ubiquitin-protein ligase MARCH-like" CG17991 11-Aug-17 DroID_v2017_08 "Drer\march5, Drer\march5l" - "Cele\marc-2, Cele\M110.3" Xtro\march5 Mmus\March5 Hsap\MARCH5 viable DRSC15294 E -0.712540775 -0.010846381 -2.085254885 0.499660178 0.352392115 -0.411384865 FBgn0267089 CR45533 - http://flybase.org/reports/FBgn0267089 non_protein_coding_gene - - - CR45533 - CR45533 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029856 CG11700 - http://flybase.org/reports/FBgn0029856 protein_coding_gene protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000003962 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype negative regulation of reproductive process ; GO:2000242 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000003962 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG11700, poly-ub, Ubiquitin, ESTS:199A6T, ESTS:143G11T, anon-sts41, CR11700, Ubi-p5E5" "IPR019954:Ubiquitin conserved site, IPR000626:Ubiquitin domain, IPR019956:Ubiquitin, IPR029071:Ubiquitin-related domain" CG11700 11-Aug-17 DroID_v2017_08 "Drer\nedd8l, Drer\uba52, Drer\si:ch211-202a12.4, Drer\ubc, Drer\kxd1, Drer\zfand4, Drer\isg15, Drer\nedd8, Drer\ubb, Drer\zgc:56596, Drer\faub, Drer\faua" Scer\UBI4 "Cele\F52C6.3, Cele\ubq-1, Cele\ubq-2, Cele\ned-8, Cele\kxd-1, Cele\F52C6.2" "Xtro\nedd8, Xtro\ubl4a, Xtro\fau, Xtro\ubc, Xtro\zfand4, Xtro\uba52, Xtro\rps27a, Xtro\kxd1" "Mmus\Isg15, Mmus\Ubd, Mmus\Oas1a, Mmus\Oasl1, Mmus\Rps27a, Mmus\Oasl2, Mmus\Oas2, Mmus\Oas3, Mmus\Ubb, Mmus\Ubc, Mmus\Nedd8, Mmus\Oas1g, Mmus\Ubl4a, Mmus\Fau, Mmus\Ubl4b, Mmus\Zfand4" "Hsap\NEDD8, Hsap\OAS3, Hsap\OAS2, Hsap\ISG15, Hsap\UBL4A, Hsap\RPS27A, Hsap\UBL4B, Hsap\UBA52, Hsap\UBB, Hsap\OAS1, Hsap\ZFAND4, Hsap\UBD, Hsap\UBC, Hsap\OASL" "viable,short lived,male" DRSC17794 IEK -2.64849259 -0.379170482 13.06703615 -3.640441366 -6.451732882 -2.769467211 FBgn0058269 CG40269 - http://flybase.org/reports/FBgn0058269 protein_coding_gene - - - CG40269 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002688 mbmB mushroom body miniature B http://flybase.org/reports/FBgn0002688 - gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "rem, mbmB[N806], mbmB, mbm[B]" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,behavior defective,locomotor behavior defective,female limited,partially lethal - majority die" "ellipsoid body,nodulus,adult central complex,calyx of larval mushroom body,lobe system of adult mushroom body,adult mushroom body,calyx of adult mushroom body" FBgn0028200 l(3)S019203 lethal (3) S019203 http://flybase.org/reports/FBgn0028200 gene - - - "l(3)S141715, 1426/01, 1417/15, 1367/03, 1232/13, 1145/13, 1026/09, 1003/03, 0955/15, 0281/08, 0229/11, 0192/03, 0019/06, l(3)S019203" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0025592 Gk1 Glycerol kinase 1 http://flybase.org/reports/FBgn0025592 FBgn0035108 protein_coding_gene glycerol kinase activity ; GO:0004370 | inferred from mutant phenotype glycerol kinase activity ; GO:0004370 | inferred from sequence or structural similarity with HGNC:4289 triglyceride metabolic process ; GO:0006641 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 glycerol-3-phosphate biosynthetic process ; GO:0046167 | inferred from mutant phenotype glycerol metabolic process ; GO:0006071 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 glycerol-3-phosphate biosynthetic process ; GO:0046167 | inferred from sequence or structural similarity with HGNC:4289 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 "CG18374, dGyk, Gyk, Gk1" "IPR018483:Carbohydrate kinase, FGGY, conserved site, IPR018484:Carbohydrate kinase, FGGY, N-terminal, IPR018485:Carbohydrate kinase, FGGY, C-terminal, IPR005999:Glycerol kinase, IPR000577:Carbohydrate kinase, FGGY" CG18374 11-Aug-17 DroID_v2017_08 "Drer\zgc:172295, Drer\shpk, Drer\gk5" Scer\GUT1 "Cele\T25C8.1, Cele\R11F4.1, Cele\C55B6.1" "Xtro\gk, Xtro\shpk" "Mmus\Gk2, Mmus\Gk, Mmus\Gk5, Mmus\Shpk, Mmus\Gykl1" "Hsap\SHPK, Hsap\GK5, Hsap\GK2, Hsap\GK" "chemical sensitive,fertile,recessive" DRSC08534 K 0.544527395 -1.37606805 0.10335999 0.099666296 -0.264762194 2.158484 FBgn0026756 Ugt37a1 UDP-glycosyltransferase 37a1 http://flybase.org/reports/FBgn0026756 FBgn0032855 protein_coding_gene UDP-glycosyltransferase activity ; GO:0008194 | inferred from sequence or structural similarity with UniProtKB:P18569 glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with UniProtKB:P18569 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 integral component of membrane ; GO:0016021 | inferred from sequence model "CG11012, DmUgt37a1, 38C.41, DmeUgt37a1, Ugt37a1" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG11012 11-Aug-17 DroID_v2017_08 "Drer\zgc:172315, Drer\ugt2b3, Drer\ugt2b5, Drer\ugt2a6, Drer\ugt2b6, Drer\ugt5b3, Drer\ugt2a2, Drer\ugt5c1, Drer\ugt5d1, Drer\ugt5a1, Drer\ugt2b1, Drer\ugt5g1, Drer\ugt5b6, Drer\ugt5b1, Drer\ugt5f1, Drer\ugt1b2, Drer\ugt1b4, Drer\ugt5g2, Drer\ugt5e1, Drer\ugt1b7, Drer\ugt1b5, Drer\ugt8, Drer\ugt5c2, Drer\ugt5b2, Drer\ugt5a4, Drer\ugt1ab, Drer\ugt1b3, Drer\ugt5a5, Drer\ugt2a5, Drer\ugt5a2, Drer\ugt5c3" Scer\ATG26 "Cele\ugt-59, Cele\ugt-41, Cele\ugt-58, Cele\ugt-50, Cele\ugt-44, Cele\ugt-17, Cele\ugt-14, Cele\ugt-11, Cele\ugt-18, Cele\ugt-45, Cele\ugt-61, Cele\ugt-22, Cele\ugt-24, Cele\ugt-40, Cele\ugt-56, Cele\ugt-10, Cele\ugt-37, Cele\ugt-8, Cele\K04A8.10, Cele\ugt-52, Cele\F10D2.8, Cele\ugt-49, Cele\ugt-9, Cele\ugt-43, Cele\ugt-39, Cele\ugt-51, Cele\ugt-5, Cele\ugt-3, Cele\ugt-36, Cele\ugt-29, Cele\ugt-13, Cele\H23N18.4, Cele\ugt-38, Cele\ugt-4, Cele\ugt-31, Cele\ugt-60, Cele\ugt-34, Cele\ugt-26, Cele\ugt-23, Cele\ugt-7, Cele\Y43D4A.2, Cele\ugt-42, Cele\C55H1.1, Cele\ugt-20, Cele\ugt-33, Cele\ugt-30, Cele\C03A7.13, Cele\ugt-27, Cele\ugt-1, Cele\ugt-65, Cele\ugt-57, Cele\ugt-2, Cele\ugt-6, Cele\ugt-25, Cele\ugt-63, Cele\ugt-12, Cele\ugt-53, Cele\ugt-55, Cele\ugt-28, Cele\C23G10.6, Cele\ugt-16, Cele\ugt-21, Cele\ugt-35, Cele\ugt-48, Cele\ugt-32, Cele\ugt-62, Cele\ugt-54, Cele\C03A7.12, Cele\ugt-15, Cele\ugt-46, Cele\ugt-47, Cele\ugt-19" "Xtro\ugt2a1, Xtro\ugt8, Xtro\ugt3a2, Xtro\ugt1a6, Xtro\ugt2b4" "Mmus\Ugt2b36, Mmus\Ugt1a7c, Mmus\Ugt1a9, Mmus\Ugt2b1, Mmus\Ugt8a, Mmus\Ugt2b37, Mmus\Ugt1a2, Mmus\Ugt2b35, Mmus\Ugt2b38, Mmus\Ugt1a6b, Mmus\Ugt1a1, Mmus\Ugt2a1, Mmus\Ugt2a3, Mmus\Ugt3a2, Mmus\Ugt2b34, Mmus\Ugt2b5, Mmus\Ugt3a1, Mmus\Ugt1a5" "Hsap\UGT1A6, Hsap\UGT1A1, Hsap\UGT2A2, Hsap\UGT1A9, Hsap\UGT1A3, Hsap\UGT2B4, Hsap\UGT1A7, Hsap\UGT2B7, Hsap\UGT1A5, Hsap\UGT1A4, Hsap\UGT3A2, Hsap\UGT2B10, Hsap\UGT8, Hsap\UGT2B11, Hsap\UGT2A3, Hsap\UGT2B17, Hsap\UGT1A8, Hsap\UGT2B15, Hsap\UGT1A10, Hsap\UGT2B28, Hsap\UGT3A1" viable FBgn0061090 l(3)S011406 lethal (3) S011406 http://flybase.org/reports/FBgn0061090 gene - - - "0114/06, l(3)S011406" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026238 gus gustavus http://flybase.org/reports/FBgn0026238 "FBan0002944, FBgn0033008, FBgn0033009" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P09052 inferred from physical interaction with UniProtKB:P83940 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P09052 inferred from physical interaction with UniProtKB:Q9VAQ0 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P09052 protein binding ; GO:0005515 | inferred from physical interaction with vas intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001496 pole cell migration ; GO:0007280 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay Cul5-RING ubiquitin ligase complex ; GO:0031466 | inferred from direct assay elongin complex ; GO:0070449 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay pole plasm ; GO:0045495 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG2944, dmSSB4, i25, A11, CG2946, gus, GUS, Gus" "IPR001496:SOCS box domain, IPR001870:B30.2/SPRY domain, IPR003877:SPRY domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG2944 11-Aug-17 DroID_v2017_08 "Drer\spsb1, Drer\spsb3b, Drer\spsb4b, Drer\spsb4a, Drer\fbxo45" - "Cele\spsb-2, Cele\spsb-1" "Xtro\fbxo45, Xtro\spsb4, Xtro\spsb1" "Mmus\Fbxo45, Mmus\Spsb1, Mmus\Spsb4, Mmus\Spsb2" "Hsap\FBXO45, Hsap\SPSB2, Hsap\SPSB1, Hsap\SPSB4" " embryonic stage | 0-4 hr , adult stage | female " " adult stage && O | stage S6-9 , adult stage " " oocyte

, germarium && nurse cell

, stage S10 oocyte

" "visible,lethal - all die before end of embryonic stage,maternal effect,partially lethal - majority live,viable,fertile,female sterile,some die during embryonic stage" "pole cell,maternal effect,embryo,egg,wing blade,wing margin,ectopic,wing vein,oocyte,oocyte nucleus,stage S8 oocyte,stage S9 oocyte,chorion,dorsal appendage,abdominal ventral denticle belt" DRSC04886 E 1.402502072 -0.681186038 2.250235052 -1.772525788 0.381602547 0.079378174 FBgn0065066 snoRNA:Me28S-A2564 - http://flybase.org/reports/FBgn0065066 snoRNA_gene - - - "Dm-442, snoR442, CR33778, snoRNA:Me28S-A2564, Me28S-A2564(SnoR442), snoRNA:442" - CR33778 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022704 Ca-3 Carbonic anhydrase-3 http://flybase.org/reports/FBgn0022704 - gene - - - "CA-3, Ca-3" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030683 CG8239 - http://flybase.org/reports/FBgn0030683 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006204 diphosphomevalonate decarboxylase activity ; GO:0004163 | inferred from sequence or structural similarity with HGNC:7529 "isopentenyl diphosphate biosynthetic process, mevalonate pathway ; GO:0019287 | inferred from electronic annotation with InterPro:IPR029765 isoprenoid biosynthetic process ; GO:0008299 | inferred from sequence or structural similarity with HGNC:7529" cytosol ; GO:0005829 | inferred from electronic annotation with InterPro:IPR029765 cellular_component ; GO:0005575 | no biological data available "CG8239, MVD, MevPPD" "IPR005935:Diphosphomevalonate/phosphomevalonate decarboxylase, IPR006204:GHMP kinase N-terminal domain, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR013750:GHMP kinase, C-terminal domain, IPR029765:Diphosphomevalonate decarboxylase, IPR020568:Ribosomal protein S5 domain 2-type fold" CG8239 11-Aug-17 DroID_v2017_08 Drer\mvda Scer\MVD1 Cele\Y48B6A.13 Xtro\mvd Mmus\Mvd Hsap\MVD "viable,visible" tormogen cell FBgn0039417 CG6073 - http://flybase.org/reports/FBgn0039417 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - CG6073 "IPR007205:Protein HGH1 N-terminal, IPR007206:Protein HGH1 C-terminal, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG6073 11-Aug-17 DroID_v2017_08 Drer\hgh1 Scer\HGH1 Cele\Y54H5A.2 Xtro\hgh1 Mmus\Hgh1 Hsap\HGH1 viable FBgn0083020 snoRNA:Psi18S-640g snoRNA:Psi18S-640g http://flybase.org/reports/FBgn0083020 snoRNA_gene - - - "snoRNA:Psi18S-640g, psi18s-640g, CR34585" - CR34585 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001511 l(1)10Fe lethal (1) 10Fe http://flybase.org/reports/FBgn0001511 - gene - - - "17, l(1)L17, l(1)10Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,germline clone,recessive,rescuable maternal effect,neurogenic phenotype,partially" FBgn0002803 ms(1)19Fb male sterile (1) 19Fb http://flybase.org/reports/FBgn0002803 - gene - - - "ms(1)C, ms(1)19Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0016854 l(1)N35 lethal (1) N35 http://flybase.org/reports/FBgn0016854 - gene - - - "l(1)N35, N35" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005577 ota5 olfactory trap abnormal 5 http://flybase.org/reports/FBgn0005577 - gene molecular_function ; GO:0003674 | no biological data available chemosensory behavior ; GO:0007635 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ota5 - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,male" FBgn0060737 l(3)S066905 lethal (3) S066905 http://flybase.org/reports/FBgn0060737 gene - - - "0669/05, l(3)S066905" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0016867 l(2)39ADe lethal (2) 39ADe http://flybase.org/reports/FBgn0016867 - gene - - - "N6, l(2)39ADe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085492 CG40505 - http://flybase.org/reports/FBgn0085492 protein_coding_gene - - - CG40505 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000291 Cg98F-99A Collagen-like 88F-99A http://flybase.net/reports/FBgn0000291.html gene "DCg5, Cg5" 11-Aug-17 DroID_v2017_08 FBgn0263956 BG01085 - http://flybase.org/reports/FBgn0263956 gene - - - BG01085 - - 11-Aug-17 DroID_v2017_08 - - - - - - "long lived,male limited" FBgn0267496 2SrRNA:CR45836 2S ribosomal RNA:CR45836 http://flybase.org/reports/FBgn0267496 rRNA_gene - - - "2SrRNA:CR45836, CR45836" - CR45836 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266106 mei-105 meiotic 105 http://flybase.org/reports/FBgn0266106 gene - female meiotic division ; GO:0007143 | inferred from mutant phenotype - mei-105 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,meiotic cell cycle defective,female" FBgn0082995 snoRNA:Psi28S-1837b snoRNA:Psi28S-1837b http://flybase.org/reports/FBgn0082995 snoRNA_gene - - - "snoRNA:Psi28S-1837b, Psi28S-1837b, psi28S-1837b, CR34639" - CR34639 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0041243 Gr43a Gustatory receptor 43a http://flybase.org/reports/FBgn0041243 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 cellular response to fructose stimulus ; GO:0071332 | inferred from mutant phenotype chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement adult feeding behavior ; GO:0008343 | inferred from mutant phenotype sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 regulation of appetite ; GO:0032098 | inferred from mutant phenotype response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 regulation of feeding behavior ; GO:0060259 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "DmGr43a, CG1712, Gr43C1, 43C1, 43C.1, GR43C.1, Gr43a, GR43a, gr43a" IPR013604:7TM chemoreceptor CG1712 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - "feeding behavior defective,taste perception defective,viable" prothoracic leg taste bristle chemosensory neuron FBgn0044009 Su(rst)B183 Su(rst)B183 http://flybase.org/reports/FBgn0044009 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B183, Su(rst)B183" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0033504 CAP CAP http://flybase.org/reports/FBgn0033504 protein_coding_gene - cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR028516 cell migration ; GO:0016477 | inferred from electronic annotation with InterPro:IPR028516 actin filament organization ; GO:0007015 | inferred from electronic annotation with InterPro:IPR028516 muscle attachment ; GO:0016203 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype sensory perception of mechanical stimulus ; GO:0050954 | inferred from mutant phenotype - "CAP, CAP/Vinexin, DCAP, CG18409, Rexin, rexin, CG3451, CG18408, cap" "IPR001452:SH3 domain, IPR003127:SoHo domain, IPR028516:Sorbin and SH3 domain-containing protein 2" CG18408 11-Aug-17 DroID_v2017_08 "Drer\sorbs2b, Drer\sorbs2a, Drer\sorbs3, Drer\bin2a, Drer\sorbs1, Drer\LOC101885672" - Cele\sorb-1 "Xtro\sorbs1, Xtro\sorbs2" "Mmus\Sorbs3, Mmus\Sorbs1, Mmus\Sorbs2" "Hsap\SORBS2, Hsap\MDC1, Hsap\SORBS3, Hsap\SORBS1" "viable,fertile,behavior defective,auditory perception defective,neuroanatomy defective,lethal - all die before end of embryonic stage,partially,some die during embryonic stage" "scolopale cell,Johnston organ,muscle attachment site,muscle attachment site | larval stage" FBgn0260458 PGRP-LD Peptidoglycan recognition protein LD http://flybase.org/reports/FBgn0260458 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with UniProtKB:O76537 immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement innate immune response ; GO:0045087 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | non-traceable author statement "CG32912, CG33717, CG5523, PGRP-LD" "IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR002502:N-acetylmuramoyl-L-alanine amidase domain" CG33717 11-Aug-17 DroID_v2017_08 "Drer\pglyrp6, Drer\pglyrp5, Drer\pglyrp2" - - "Xtro\pglyrp1, Xtro\pglyrp2, Xtro\pglyrp1" "Mmus\Pglyrp3, Mmus\Pglyrp2, Mmus\Pglyrp1, Mmus\Pglyrp4" "Hsap\PGLYRP2, Hsap\PGLYRP4, Hsap\PGLYRP1, Hsap\PGLYRP3" DRSC10512 I -2.112498321 0.092584615 0.287240874 0.655018972 0.069938496 -0.054833937 FBgn0265510 CR44372 - http://flybase.org/reports/FBgn0265510 non_protein_coding_gene - - - CR44372 - CR44372 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020236 ATPCL ATP citrate lyase http://flybase.org/reports/FBgn0020236 "FBgn0010490, FBgn0044698" protein_coding_gene cofactor binding ; GO:0048037 | inferred from electronic annotation with InterPro:IPR003781 ATP citrate synthase activity ; GO:0003878 | inferred from biological aspect of ancestor with PANTHER:PTN000563493 ATP citrate synthase activity ; GO:0003878 | inferred from sequence or structural similarity citrate metabolic process ; GO:0006101 | inferred from electronic annotation with InterPro:IPR014608 fatty acid biosynthetic process ; GO:0006633 | inferred from biological aspect of ancestor with PANTHER:PTN000563493 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype acetyl-CoA biosynthetic process ; GO:0006085 | inferred from biological aspect of ancestor with PANTHER:PTN000563493 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000563493 lipid particle ; GO:0005811 | inferred from direct assay citrate lyase complex ; GO:0009346 | inferred from biological aspect of ancestor with PANTHER:PTN000563493 "CG8322, l(2)k09217, n(2)k09217, l(2)01466, DmATPCL, BcDNA:LD21334, anon-WO0140519.179, ATPCL, dATPCL, ACL" "IPR003781:CoA-binding, IPR005811:ATP-citrate lyase/succinyl-CoA ligase, IPR013650:ATP-grasp fold, succinyl-CoA synthetase-type, IPR014608:ATP-citrate synthase, IPR016102:Succinyl-CoA synthetase-like, IPR016143:Citrate synthase-like, small alpha subdomain, IPR017440:ATP-citrate lyase/succinyl-CoA ligase, active site, IPR016040:NAD(P)-binding domain, IPR017866:Succinyl-CoA synthetase, beta subunit, conserved site, IPR033847:ATP-citrate lyase/succinyl-CoA ligase, conserved site, IPR028091:FAM91, N-terminal domain, IPR028097:FAM91, C-terminal domain, IPR002020:Citrate synthase, IPR016142:Citrate synthase-like, large alpha subdomain, IPR032263:ATP-citrate synthase, citrate-binding domain" CG8322 11-Aug-17 DroID_v2017_08 "Drer\aclya, Drer\aclyb" Scer\LSC1 "Cele\acly-1, Cele\acly-2" Xtro\acly Mmus\Acly Hsap\ACLY "viable,lethal,recessive,partially lethal - majority die,visible,some die during pupal stage" "trichogen cell,supernumerary,mesothoracic tergum" FBgn0051663 CG31663 - http://flybase.org/reports/FBgn0051663 protein_coding_gene - - - "CG15360, CG15359, BcDNA:GH27779, CG31663" "IPR024989:Major facilitator superfamily associated domain, IPR020846:Major facilitator superfamily domain" CG31663 11-Aug-17 DroID_v2017_08 "Drer\mfsd6l, Drer\mfsd6a, Drer\mfsd6b" - Cele\R13A5.9 "Xtro\mfsd6l, Xtro\mfsd6" "Mmus\Mfsd6, Mmus\Mfsd6l" "Hsap\MFSD6L, Hsap\MFSD6" "partially lethal - majority die,some die during pupal stage" FBgn0011472 l(3)neo39 lethal (3) neo39 http://flybase.org/reports/FBgn0011472 - gene - - - l(3)neo39 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039335 Vps33B Vacuolar protein sorting 33B http://flybase.org/reports/FBgn0039335 protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with Vps16B syntaxin binding ; GO:0019905 | inferred from physical interaction with Syx16, Syx7" vesicle docking involved in exocytosis ; GO:0006904 | inferred from electronic annotation with InterPro:IPR001619 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000004388 regulation of SNARE complex assembly ; GO:0035542 | inferred from sequence or structural similarity with SGD:S000004388 immune response ; GO:0006955 | inferred from mutant phenotype CORVET complex ; GO:0033263 | inferred from sequence or structural similarity with SGD:S000004388 HOPS complex ; GO:0030897 | inferred from direct assay HOPS complex ; GO:0030897 | inferred from sequence or structural similarity with SGD:S000004388 "Vps33B, dVps33B, CG5127, VPS33b, Vps 33B, Vps33b" IPR001619:Sec1-like protein CG5127 11-Aug-17 DroID_v2017_08 "Drer\vps33a, Drer\vps33b" Scer\VPS33 "Cele\vps-33.2, Cele\vps-33.1" Xtro\vps33b "Mmus\Vps33b, Mmus\Vps33a" "Hsap\VPS33B, Hsap\VPS33A" "viable,immune response defective" FBgn0004029 ww wider wing http://flybase.org/reports/FBgn0004029 - gene - - - ww - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,female,reduced,female fertile,male fertile" wing FBgn0010101 amiel amiel http://flybase.org/reports/FBgn0010101 - gene - - - "Amiel, amiel" - - 11-Aug-17 DroID_v2017_08 - - - - - - "courtship behavior defective,male,recessive,mating defective" FBgn0003664 Thar Thickened arista http://flybase.org/reports/FBgn0003664 - gene - - - "Thar, Ta" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semidominant,lethal,recessive" arista FBgn0030508 CG15760 - http://flybase.org/reports/FBgn0030508 protein_coding_gene signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN001805617 - integral component of organelle membrane ; GO:0031301 | inferred from biological aspect of ancestor with PANTHER:PTN001805617 CG15760 - CG15760 11-Aug-17 DroID_v2017_08 "Drer\vopp1, Drer\si:dkey-24c2.9" - - - Mmus\Vopp1 Hsap\VOPP1 viable FBgn0263993 CG43736 - http://flybase.org/reports/FBgn0263993 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026314 "CG43736, CG33691, CG4571, CG4564, CG32737-ORFA, CG32737 ORF A, CG32737, CG33692, CG14433, CG32737-ORFB" "IPR026314:YLP motif-containing protein 1, IPR015943:WD40/YVTN repeat-like-containing domain" CG43736 11-Aug-17 DroID_v2017_08 - - Cele\F30F8.5 - - - FBgn0060558 l(3)S097301b lethal (3) S097301b http://flybase.org/reports/FBgn0060558 gene - - - "l(3)097301, 0973/01, l(3)S097301b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0262301 mir-979 mir-979 stem loop http://flybase.org/reports/FBgn0262301 miRNA_gene - - - "dme-mir-979, mir-979, CR43008, miR-979" - CR43008 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0039041 CG13838 - http://flybase.org/reports/FBgn0039041 protein_coding_gene - - - CG13838 IPR022788:Uncharacterised protein family UPF0184 CG13838 11-Aug-17 DroID_v2017_08 Drer\gb:bc139872 - Cele\C15C7.5 - Mmus\1110008P14Rik Hsap\C9orf16 FBgn0042687 Tirant\env Tirant element env http://flybase.org/reports/FBgn0042687 transposable_element_gene - - - "ORF3, Tirant\env, env" IPR009882:Gypsy - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067871 Mod(Prat:bw)3-4 Mod(Prat:bw)3-4 http://flybase.org/reports/FBgn0067871 gene - - - "Mod-3-4, Mod(Prat:bw)3-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - enhancer of variegation FBgn0035194 Psf1 Psf1 http://flybase.org/reports/FBgn0035194 protein_coding_gene 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA strand elongation involved in mitotic DNA replication ; GO:1902983 | inferred from biological aspect of ancestor with PANTHER:PTN000308454 positive regulation of G1/S transition of mitotic cell cycle ; GO:1900087 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype GINS complex ; GO:0000811 | inferred from direct assay "CG9187, Psf1, CG9187-PA, psf1" "IPR005339:GINS complex, subunit Psf1, IPR021151:GINS subunit, domain A" CG9187 11-Aug-17 DroID_v2017_08 Drer\gins1 Scer\PSF1 Cele\psf-1 Xtro\gins1 Mmus\Gins1 Hsap\GINS1 "lethal,neuroanatomy defective,viable,visible" "rhabdomere R7,embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0013644 mfs(2)ry10 mfs(2)ry10 http://flybase.org/reports/FBgn0013644 - gene - - - "mfs(2)10, mfs(2)ry10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female sterile" FBgn0062519 substance-P substance P http://flybase.org/reports/FBgn0062519 gene neuropeptide hormone activity ; GO:0005184 | inferred from direct assay - - "SP, substance-P" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038130 CG8630 - http://flybase.org/reports/FBgn0038130 protein_coding_gene "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water ; GO:0016717 | inferred from electronic annotation with InterPro:IPR015876" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015876 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804 - CG8630 "IPR005804:Fatty acid desaturase domain, IPR015876:Acyl-CoA desaturase" CG8630 11-Aug-17 DroID_v2017_08 "Drer\scd, Drer\scdb" Scer\OLE1 "Cele\fat-6, Cele\fat-7, Cele\fat-5" Xtro\scd "Mmus\Scd4, Mmus\Scd1, Mmus\Scd2, Mmus\Scd3" "Hsap\SCD5, Hsap\SCD" lethal DRSC16441 EK 1.150896546 0.343532663 2.859822058 -0.968624992 -0.567219876 -1.568681694 FBgn0029529 CG13365 - http://flybase.org/reports/FBgn0029529 protein_coding_gene - - - "BcDNA:LP07417, CG13365" - CG13365 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0265854 CR44643 - http://flybase.org/reports/FBgn0265854 non_protein_coding_gene - - - CR44643 - CR44643 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016648 En(en)eg-1 En(en)eg-1 http://flybase.org/reports/FBgn0016648 - gene - - - En(en)eg-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing vein,trichome of the posterior wing margin" FBgn0266221 CR44916 - http://flybase.org/reports/FBgn0266221 non_protein_coding_gene - - - CR44916 - CR44916 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264824 CR44032 - http://flybase.org/reports/FBgn0264824 non_protein_coding_gene - - - "CG44032, CR44032" - CR44032 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031538 CG3246 - http://flybase.org/reports/FBgn0031538 protein_coding_gene lipid binding ; GO:0008289 | inferred from electronic annotation with InterPro:IPR017943 - - CG3246 "IPR017943:Bactericidal permeability-increasing protein, alpha/beta domain, IPR010562:Haemolymph juvenile hormone binding, IPR020234:Mite allergen, group-7" CG3246 11-Aug-17 DroID_v2017_08 - - - - - - "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0060616 l(3)S089707b lethal (3) S089707b http://flybase.org/reports/FBgn0060616 gene - - - "0897/07, l(3)S089707b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053459 CG33459 - http://flybase.org/reports/FBgn0053459 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "HDC06756, CG33459" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG33459 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\prss56" - "Cele\svh-1, Cele\try-1, Cele\try-3" - "Mmus\Egfbp2, Mmus\Klk1b9, Mmus\Prss54, Mmus\Klk1b5, Mmus\Prss56" Hsap\PRSS56 "lethal - all die before end of larval stage,some die during third instar larval stage" FBgn0260783 9-220 - http://flybase.org/reports/FBgn0260783 gene - - - 9-220 - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0025816 MBP1 MBT-binding protein 1 http://flybase.org/reports/FBgn0025816 - gene - - - MBP1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052183 Ccn Ccn http://flybase.org/reports/FBgn0052183 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG32183, dCCN, CG13736, CG13735, Ccn" "IPR001007:VWFC domain, IPR006207:Cystine knot, C-terminal" CG32183 11-Aug-17 DroID_v2017_08 "Drer\wisp2, Drer\ctgfa, Drer\cyr61l1, Drer\zgc:85866, Drer\wisp1a, Drer\wisp1b, Drer\wisp3, Drer\si:ch211-106h11.3, Drer\cyr61, Drer\ctgfb" - Cele\crm-1 "Xtro\cyr61, Xtro\nov, Xtro\crim1, Xtro\wisp2, Xtro\ctgf, Xtro\wisp1" "Mmus\Nell1, Mmus\Wisp2, Mmus\Wisp3, Mmus\Nov, Mmus\Ctgf, Mmus\Wisp1, Mmus\Cyr61, Mmus\Bmper" "Hsap\CRIM1, Hsap\CTGF, Hsap\WISP1, Hsap\BMPER, Hsap\WISP3, Hsap\CYR61, Hsap\WISP2, Hsap\NELL2, Hsap\NOV" "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval neuroblast FBgn0259677 CG42346 - http://flybase.org/reports/FBgn0259677 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG40500-PA, CG42346, CG40500, CG41105" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR013783:Immunoglobulin-like fold, IPR003591:Leucine-rich repeat, typical subtype, IPR026906:Leucine rich repeat 5" CG42346 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-1j5.4, Drer\lrrc8c, Drer\si:zfos-323e3.4, Drer\lrrc8da, Drer\si:ch211-106h11.1, Drer\lrrc8aa, Drer\lrrc8ab" - - "Xtro\LOC100170560, Xtro\lrrc8b, Xtro\rtn4r, Xtro\lrrc8a, Xtro\lrrc8e, Xtro\tril, Xtro\lrrc8c, Xtro\lrrc8d, Xtro\rtn4rl1" "Mmus\Rtn4rl2, Mmus\Stk11ip, Mmus\Tlr11, Mmus\Lrrc8d, Mmus\Rtn4rl1, Mmus\Lrrc8e, Mmus\Lrrc8c, Mmus\Tril, Mmus\Rtn4r" "Hsap\LRRC70, Hsap\LRRC8E, Hsap\RTN4RL1, Hsap\TRIL, Hsap\RTN4RL2, Hsap\STK11IP, Hsap\LRRC8C, Hsap\LRRC8D, Hsap\RTN4R" "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell FBgn0261086 Syt14 Synaptotagmin 14 http://flybase.org/reports/FBgn0261086 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 integral component of membrane ; GO:0016021 | inferred from sequence model "CG9778, Syt14, Syt 14, dsyt14, syt14, Syt16, syt16" IPR000008:C2 domain CG9778 11-Aug-17 DroID_v2017_08 "Drer\syt14a, Drer\syt16, Drer\syt14b" - Cele\D2023.3 Xtro\syt14 "Mmus\Syt14, Mmus\Syt16" "Hsap\SYT16, Hsap\SYT14" FBgn0067321 C45 C45 http://flybase.org/reports/FBgn0067321 gene - - - C45 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,viable" chaeta FBgn0043883 mdg1\ORF mdg1 element ORF http://flybase.org/reports/FBgn0043883 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - mdg1\ORF "IPR026523:Paraneoplastic antigen Ma, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021775 mmei-1 mmei-1 http://flybase.org/reports/FBgn0021775 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "m1, mmei-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" "spermatocyte,primary spermatocyte cyst,onion stage spermatid,spermatozoon" FBgn0261594 M(3)93A Minute (3) 93A http://flybase.org/reports/FBgn0261594 gene - - - M(3)93A - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265721 CR44528 - http://flybase.org/reports/FBgn0265721 non_protein_coding_gene - - - "incRNA.435, CR44528, lincRNA.435" - CR44528 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060930 l(3)S042008 lethal (3) S042008 http://flybase.org/reports/FBgn0060930 gene - - - "0420/08, l(3)S042008" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0086442 mib2 mind bomb 2 http://flybase.org/reports/FBgn0086442 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433, InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with mib1 ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN001197468 myosin II light chain binding ; GO:0032033 | inferred from physical interaction with sqh myosin II heavy chain binding ; GO:0032038 | inferred from physical interaction with zip" myoblast fusion ; GO:0007520 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with mib1 M band ; GO:0031430 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay "mib2, CG17492, l(2)37Be, suelto, D-mibl, i115, Be, Mib-2, mib1/2" "IPR010606:Mib-herc2, IPR002110:Ankyrin repeat, IPR001841:Zinc finger, RING-type, IPR000433:Zinc finger, ZZ-type, IPR020683:Ankyrin repeat-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17492 11-Aug-17 DroID_v2017_08 "Drer\sqstm1, Drer\mib2, Drer\asb8, Drer\mib1, Drer\LOC555713, Drer\nbr1" - Cele\mib-1 "Xtro\nbr1, Xtro\mib1, Xtro\sqstm1, Xtro\mib2" "Mmus\Mib1, Mmus\Nbr1, Mmus\Sqstm1, Mmus\Asb8, Mmus\Mib2" "Hsap\NBR1, Hsap\SQSTM1, Hsap\MIB2, Hsap\MIB1" FBgn0051098 CG31098 - http://flybase.org/reports/FBgn0051098 protein_coding_gene - - - "CG10634, BcDNA:RE13429, BcDNA:GH27183, CG31098" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31098 11-Aug-17 DroID_v2017_08 - - "Cele\F59B1.10, Cele\F59B1.8" - - - viable FBgn0013247 E(var)3-12 E(var)3-12 http://flybase.org/reports/FBgn0013247 - gene - - - "E-var(3)12, E(var)3-12" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0039510 CG3339 - http://flybase.org/reports/FBgn0039510 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q8TE73 dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG3339, DHC5" "IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain" CG3339 11-Aug-17 DroID_v2017_08 "Drer\dnah9l, Drer\dnah1, Drer\dnah12, Drer\dnah3, Drer\si:dkeyp-86b9.1, Drer\dnah7l, Drer\wu:fj30b09, Drer\si:dkeyp-87a6.1, Drer\dnah7, Drer\dnah9, Drer\dync1h1, Drer\dnah2" Scer\DYN1 "Cele\dhc-1, Cele\che-3" "Xtro\LOC100497531, Xtro\dnah14, Xtro\dnah7, Xtro\dnah2" "Mmus\Dnah11, Mmus\Dnah5, Mmus\Dync2h1, Mmus\Dnah6, Mmus\Dnah2, Mmus\Dnah1, Mmus\Dnah9, Mmus\Dnah17, Mmus\Dnah10, Mmus\Dnah8, Mmus\Dnah7a, Mmus\Dnah12, Mmus\Dnah3, Mmus\Dnah7b, Mmus\Dync1h1, Mmus\Dnhd1" "Hsap\DNAH1, Hsap\DNAH7, Hsap\DNAH11, Hsap\DNAH10, Hsap\DNAH14, Hsap\DYNC1H1, Hsap\DNAH3, Hsap\DNAH6, Hsap\CCDC88B, Hsap\DNAH12, Hsap\DNAH8, Hsap\DNHD1, Hsap\DNAH5, Hsap\DNAH17, Hsap\DNAH2, Hsap\DNAH9, Hsap\DYNC2H1" viable DRSC13821 E -0.064717041 -0.092012619 1.69188237 1.00368574 0.509122396 -0.379680867 FBgn0265138 Gr22c Gustatory receptor 22c http://flybase.org/reports/FBgn0265138 protein_coding_gene taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity with Gr5a taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr22c, GR22c, CG31929, Gr2940.3, GrLU6, LU.6, GRLU.6" IPR013604:7TM chemoreceptor CG31929 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - FBgn0020341 anon-5Ca anon-5Ca http://flybase.org/reports/FBgn0020341 - gene - - - anon-5Ca - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065415 l(2)SH1550 lethal (2) SH1550 http://flybase.org/reports/FBgn0065415 gene - - - "l(2)SH1550, l(2)SH2 1550" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265831 CR44620 - http://flybase.org/reports/FBgn0265831 non_protein_coding_gene - - - "lincRNA.986, CR44620" - CR44620 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051083 CG31083 - http://flybase.org/reports/FBgn0051083 protein_coding_gene - - - "BcDNA:RH14203, CG31083" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033827 CG17047 - http://flybase.org/reports/FBgn0033827 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17047 IPR000859:CUB domain CG17047 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035300 CG1139 - http://flybase.org/reports/FBgn0035300 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transporter activity ; GO:0015171 | inferred from direct assay amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transport ; GO:0003333 | inferred from direct assay growth ; GO:0040007 | inferred from mutant phenotype vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 CG1139 "IPR013057:Amino acid transporter, transmembrane domain" CG1139 11-Aug-17 DroID_v2017_08 "Drer\slc36a1, Drer\slc36a4" "Scer\AVT3, Scer\AVT4" "Cele\slc-36.3, Cele\slc-36.4, Cele\skat-1, Cele\slc-36.5, Cele\Y43F4B.7, Cele\slc-36.2" "Xtro\slc36a1, Xtro\slc36a4" "Mmus\Slc36a3, Mmus\Slc36a4, Mmus\Slc36a2, Mmus\Slc36a1, Mmus\Slc38a8" "Hsap\SLC36A1, Hsap\SLC36A2, Hsap\SLC36A4, Hsap\SLC38A8, Hsap\SLC36A3" "increased cell number,decreased cell number,increased cell size,viable" "ommatidium,eye,wing" FBgn0264748 CG44006 - http://flybase.org/reports/FBgn0264748 protein_coding_gene - - - "CG44006, CG34252" "IPR032675:Leucine-rich repeat domain, L domain-like" CG44006 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020399 Mst89B Mst89B http://flybase.org/reports/FBgn0020399 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatogenesis ; GO:0007283 | inferred from expression pattern cytoplasm ; GO:0005737 | non-traceable author statement "CG6864, Mst89B" - CG6864 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | third instar , spermatogenesis && adult stage , pupal stage , adult stage " testis

viable FBgn0053200 VepD Ventrally-expressed protein D http://flybase.org/reports/FBgn0053200 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism development ; GO:0007275 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "D, CG33200, anon-EST:CL57, VepD, vepD, ventrally-expressed-protein-D" - CG33200 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage >5 , embryonic stage | stage 5 " " mesoderm

, mesoderm anlage | segmentally repeated

" FBgn0085506 CG40635 - http://flybase.org/reports/FBgn0085506 protein_coding_gene "protein kinase regulator activity ; GO:0019887 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149" - "protein kinase CK2 complex ; GO:0005956 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149" CG40635 "IPR016149:Casein kinase II, regulatory subunit, alpha-helical, IPR000704:Casein kinase II, regulatory subunit" CG40635 11-Aug-17 DroID_v2017_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" - Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0052518 tRNA:Ile-AAT-2-1Psi transfer RNA:Isoleucine-AAT 2-1 pseudogene http://flybase.org/reports/FBgn0052518 pseudogene_attribute - - - "CR32518, AE002620.trna2-IleAAT, tRNA:IPsi:AAT:AE002620, chrX.trna19-IleAAT, tRNA-Ile-AAT-2-1, tRNA:Ile-AAT-2-1Psi, tRNA:CR32518:Psi" - CR32518 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259618 B1516 - http://flybase.org/reports/FBgn0259618 gene - - - B1516 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085253 CG34224 - http://flybase.org/reports/FBgn0085253 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001289" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001289" - CG34224 IPR001289:Nuclear transcription factor Y subunit A CG34224 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000829 fs(1)M8 female sterile (1) M8 http://flybase.org/reports/FBgn0000829 - gene - - - fs(1)M8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,rescuable maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0030828 CG5162 - http://flybase.org/reports/FBgn0030828 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 extracellular space ; GO:0005615 | inferred from direct assay CG5162 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG5162 11-Aug-17 DroID_v2017_08 "Drer\lipia, Drer\lipca, Drer\pla1a, Drer\lpl, Drer\lipg, Drer\LOC100331214, Drer\lipib, Drer\LOC101884800" - - "Xtro\lpl, Xtro\lipg" "Mmus\Pla1a, Mmus\Lipg, Mmus\Pnliprp1, Mmus\Lpl, Mmus\Lipi, Mmus\Liph, Mmus\Lipc, Mmus\Pnliprp2, Mmus\Pnlip" "Hsap\LIPH, Hsap\LIPG, Hsap\LPL, Hsap\PLA1A, Hsap\PNLIPRP2, Hsap\PNLIPRP3, Hsap\LIPC, Hsap\PNLIPRP1, Hsap\LIPI, Hsap\PNLIP" viable DRSC19935 K 0.34369369 -0.902714744 -1.295961033 0.219595043 1.569173165 -0.17514515 FBgn0060337 l(3)S144606 lethal (3) S144606 http://flybase.org/reports/FBgn0060337 gene - - - "1446/06, l(3)S144606" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0000709 fliI flightless I http://flybase.org/reports/FBgn0000709 FBgn0001732 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with HGNC:12690 inferred from sequence or structural similarity with HGNC:4620 actin binding ; GO:0003779 | inferred from sequence or structural similarity with Gel inferred from sequence or structural similarity with HGNC:12690 actin binding ; GO:0003779 | inferred from sequence or structural similarity actin filament severing ; GO:0051014 | inferred from electronic annotation with InterPro:IPR029919 adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype - "fli-I, CG1484, CT3691, FLI-I, fli, fltO, l(1)W-2, DCA3-19, w-2, EN3, fltI, W2, sdby, lDCB2-19, 15, l(1)ESHS53, l(1)19Fd, l(1)18-80, BcDNA:LD21753, fliI, fli I, Fli-I" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR007122:Villin/Gelsolin, IPR007123:Gelsolin-like domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR029919:Protein flightless-1, IPR029006:ADF-H/Gelsolin-like domain" CG1484 11-Aug-17 DroID_v2017_08 Drer\flii Scer\CYR1 Cele\fli-1 Xtro\flii Mmus\Flii Hsap\FLII embryonic stage -- adult stage "lethal,recessive,flightless,heat sensitive,flight defective,germline clone,maternal effect,non-rescuable maternal effect,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,partially lethal - majority die" "indirect flight muscle,myofibril,Z disc,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,striated muscle thin filament,embryonic abdominal segment & epidermis | germ-line clone,embryo,maternal effect,embryonic epidermis,mesoderm,gastrula embryo,germline clone,non-rescuable maternal effect,blastoderm embryo,sarcomere,striated muscle myosin thick filament,muscle cell,myofibrilMef2.PR" DRSC20578 I -0.14884126 2.114245027 -0.21130229 -0.142839063 0.841405066 -0.024045431 FBgn0259534 GG01365 - http://flybase.org/reports/FBgn0259534 gene - - - GG01365 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,proximal,tarsal segment,wing vein,chaeta,ectopic" FBgn0036448 mop myopic http://flybase.org/reports/FBgn0036448 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from sequence model protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000242 neuron remodeling ; GO:0016322 | inferred from mutant phenotype positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | inferred from genetic interaction with Ras85D antimicrobial peptide production ; GO:0002775 | inferred from mutant phenotype regulation of growth ; GO:0040008 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype vesicle ; GO:0031982 | inferred from direct assay endosome ; GO:0005768 | inferred from direct assay "CG9311, mop, sfv, Mop" "IPR025304:ALIX V-shaped domain, IPR000242:PTP type protein phosphatase, IPR004328:BRO1 domain, IPR029021:Protein-tyrosine phosphatase-like" CG9311 11-Aug-17 DroID_v2017_08 "Drer\ptpn18, Drer\ptpn22, Drer\ptpn23b, Drer\ptpn2b, Drer\pdcd6ip, Drer\rhpn2, Drer\ptpn2a, Drer\ptpn5, Drer\ptpn23a, Drer\ptprga, Drer\ptprz1b, Drer\rhpn1, Drer\ca16b, Drer\ptprr, Drer\ptpn1, Drer\ca16c" "Scer\PTP1, Scer\RIM20, Scer\PTP2, Scer\BRO1, Scer\PTP3" "Cele\alx-1, Cele\ego-2" "Xtro\ptpn12, Xtro\pdcd6ip, Xtro\ptpn1, Xtro\rhpn2, Xtro\ptpn23, Xtro\ptpn22, Xtro\ptprz1, Xtro\ptprr, Xtro\ptpn2" "Mmus\Rhpn1, Mmus\Ptpn22, Mmus\Ptpn18, Mmus\Ptpn23, Mmus\Ptprr, Mmus\Ptpn20, Mmus\Ptprg, Mmus\Pdcd6ip, Mmus\Ptpn2, Mmus\Ptpn5, Mmus\Rhpn2, Mmus\Ptpn7, Mmus\Ptpn12, Mmus\Ptpn1" "Hsap\PTPRG, Hsap\RHPN1, Hsap\PTPN23, Hsap\PTPN22, Hsap\PTPN7, Hsap\PTPN12, Hsap\PTPN2, Hsap\PTPN5, Hsap\PDCD6IP, Hsap\PTPN20, Hsap\PTPN1, Hsap\RHPN2, Hsap\PTPRR, Hsap\PTPN18" "lethal,recessive,size defective,somatic clone,visible,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,increased cell number" "eye,somatic clone,wing vein,eye photoreceptor cell,eye disc,inter-ommatidial cell,supernumerary" FBgn0011985 tRNA:Ser-AGA-2-3 transfer RNA:Serine-AGA 2-3 http://flybase.org/reports/FBgn0011985 "FBgn0003831, FBgn0011968, FBgn0011979, FBgn0051734, FBgn0060064" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "777-4, tRNA[Ser][[7]], tRNA[[7]][Ser], tRNA[Ser], AE002638.trna14-SerAGA, tRNA:S:AGA:AE002638-b, CR31734, tRNA:ser, tRNA:S, tRNA:S7, tRNA:ser7, tRNA:ser7:23Eb, tRNA[[Ser]], chr2L.trna7-SerAGA, tRNA-Ser-AGA-2-3, tRNA:Ser-AGA-2-3, tRNA:S7:23Eb, UCU" - CR31734 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051166 tRNA:Ser-GCT-2-5 transfer RNA:Serine-GCT 2-5 http://flybase.org/reports/FBgn0051166 tRNA_gene AGC codon-amino acid adaptor activity ; GO:0033446 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033446 cytosol ; GO:0005829 | inferred by curator from GO:0033446 "tRNA[Ser][[2b]], AE002708.trna27-SerGCT, tRNA:S:GCT:AE002708-b, tRNA:ser, tRNA:S, tRNA:ser2b:94A, tRNA:ser2b, tRNA:S2b, tRNA:S2b:94A, CR31166, tRNA[[Ser]], chr3R.trna33-SerGCT, tRNA-Ser-GCT-2-5, tRNA:Ser-GCT-2-5, tRNA:CR31166, AGC" - CR31166 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000402 cxb calyx bulging http://flybase.org/reports/FBgn0000402 - gene - - - cxb - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,behavior defective" "ellipsoid body,nodulus,lobe system of adult mushroom body,calyx of adult mushroom body" FBgn0051631 tRNA:Arg-CCT-1-1 transfer RNA:Arginine-CCT 1-1 http://flybase.org/reports/FBgn0051631 tRNA_gene AGG codon-amino acid adaptor activity ; GO:0033448 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033448 cytosol ; GO:0005829 | inferred by curator from GO:0033448 "AE002690.trna1-ArgCCT, tRNA:R:CCT:AE002690, CR31631, chr2L.trna9-ArgCCT, tRNA-Arg-CCT-1-1, tRNA:Arg-CCT-1-1, tRNA:CR31631, AGG" - CR31631 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0029027 l(3)77ABd lethal (3) 77ABd http://flybase.org/reports/FBgn0029027 gene - - - l(3)77ABd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001306 Kg Kugel http://flybase.org/reports/FBgn0001306 - gene - - - "Ch, Ch[V], Kg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,reduced" "larva,pupa,adult" FBgn0001723 l(1)ESHS44 lethal (1) ESHS44 http://flybase.org/reports/FBgn0001723 - gene - - - l(1)ESHS44 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265742 CR44549 - http://flybase.org/reports/FBgn0265742 non_protein_coding_gene - - - CR44549 - CR44549 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266930 CR45381 - http://flybase.org/reports/FBgn0266930 non_protein_coding_gene - - - CR45381 - CR45381 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034988 cN-IIIB cytosolic 5'-nucleotidase IIIB http://flybase.org/reports/FBgn0034988 protein_coding_gene magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR006434 nucleotidase activity ; GO:0008252 | inferred from direct assay 5'-nucleotidase activity ; GO:0008253 | inferred from direct assay dephosphorylation ; GO:0016311 | inferred from direct assay ribonucleoside monophosphate catabolic process ; GO:0009158 | inferred from direct assay guanosine-containing compound catabolic process ; GO:1901069 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "cNIII-like, cN-IIIB, CG3362, 16769374" "IPR006434:Pyrimidine 5'-nucleotidase, eukaryotic, IPR023214:HAD-like domain" CG3362 11-Aug-17 DroID_v2017_08 Drer\nt5c3a - "Cele\Y10G11A.1, Cele\F25B5.3" "Xtro\nt5c3a, Xtro\nt5c3b" "Mmus\Nt5c3, Mmus\Nt5c3b" "Hsap\NT5C3A, Hsap\NT5C3B" "viable,fertile" FBgn0036696 CG14057 - http://flybase.org/reports/FBgn0036696 protein_coding_gene ribonuclease P activity ; GO:0004526 | inferred from electronic annotation with InterPro:IPR016819 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR002759 lateral inhibition ; GO:0046331 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern - CG14057 "IPR002759:Ribonuclease P/MRP protein subunit, IPR016819:Ribonuclease P/MRP protein subunit Pop5" CG14057 11-Aug-17 DroID_v2017_08 Drer\pop5 Scer\POP5 Cele\Y66A7A.2 - Mmus\Pop5 Hsap\POP5 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,chaeta" FBgn0060321 l(3)S146912 lethal (3) S146912 http://flybase.org/reports/FBgn0060321 gene - - - "1469/12, l(3)S146912" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0025679 Klf15 Kruppel-like factor 15 http://flybase.org/reports/FBgn0025679 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay response to silver ion ; GO:0010272 | inferred from mutant phenotype garland nephrocyte differentiation ; GO:0061321 | inferred from mutant phenotype nephrocyte diaphragm assembly ; GO:0036059 | inferred from mutant phenotype pericardial nephrocyte differentiation ; GO:0061320 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with HGNC:14536 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:14536 "CG2932, BteB2, BTEB2, Bteb2, Klf15, dKlf15" IPR013087:Zinc finger C2H2-type CG2932 11-Aug-17 DroID_v2017_08 "Drer\klf11a, Drer\sp2, Drer\egr2b, Drer\osr2, Drer\egr4, Drer\egr1, Drer\si:dkey-56e3.3, Drer\klf15, Drer\osr1, Drer\LOC108183284, Drer\zgc:173720, Drer\si:ch73-367f21.6, Drer\si:ch211-117k10.3" "Scer\MSN4, Scer\ACE2, Scer\SWI5, Scer\FZF1, Scer\MSN2, Scer\CRZ1, Scer\AZF1" "Cele\odd-2, Cele\klf-1, Cele\lsy-2, Cele\odd-1, Cele\egrh-3, Cele\egrh-1" "Xtro\sp2, Xtro\klf8, Xtro\egr3, Xtro\egr1, Xtro\osr2, Xtro\klf11, Xtro\osr1, Xtro\egr2, Xtro\klf15, Xtro\klf15.2" "Mmus\Egr3, Mmus\Osr2, Mmus\Zfp7, Mmus\Zfp629, Mmus\Egr4, Mmus\Sp2, Mmus\Egr1, Mmus\Osr1, Mmus\Zfp819, Mmus\Zfp493, Mmus\Klf15, Mmus\Klf11" "Hsap\EGR1, Hsap\ZNF491, Hsap\KLF17, Hsap\EGR2, Hsap\EGR4, Hsap\EGR3, Hsap\OSR1, Hsap\SP2, Hsap\KLF9, Hsap\ZNF140, Hsap\ZNF626, Hsap\ZNF674, Hsap\KLF11, Hsap\ZNF85, Hsap\ZNF30, Hsap\OSR2, Hsap\ZNF100, Hsap\ZNF331, Hsap\KLF15, Hsap\ZNF273, Hsap\ZNF737, Hsap\ZNF492, Hsap\ZNF254, Hsap\ZNF695" "viable,fertile" FBgn0067069 N12 N12 http://flybase.org/reports/FBgn0067069 gene - - - N12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,eye color defective,lethal,viable" "eye,pigment cell" FBgn0044119 E(rst)B92 E(rst)B92 http://flybase.org/reports/FBgn0044119 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B92, E(rst)B92" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039639 CG14512 - http://flybase.org/reports/FBgn0039639 protein_coding_gene N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity ; GO:0004577 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN002292717 dolichol-linked oligosaccharide biosynthetic process ; GO:0006488 | inferred from biological aspect of ancestor with PANTHER:PTN002292717 UDP-N-acetylglucosamine transferase complex ; GO:0043541 | inferred from biological aspect of ancestor with PANTHER:PTN000305388 "CG14512, Alg13, dAlg13" "IPR007235:Glycosyl transferase, family 28, C-terminal" CG14512 11-Aug-17 DroID_v2017_08 "Drer\alg13, Drer\zgc:92907" Scer\ALG13 Cele\algn-13 Xtro\alg13 "Mmus\Alg13, Mmus\Glt28d2, Mmus\Otud4" "Hsap\ALG13, Hsap\OTUD4" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC14864 IE -2.520487323 0.397045261 1.578561822 0.708834874 0.474462802 -0.116763955 FBgn0262974 CR43285 - http://flybase.org/reports/FBgn0262974 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43285, CR43285" - CR43285 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023160 Su(mg)1-8 Suppressor of modifier of gypsy 1-8 http://flybase.org/reports/FBgn0023160 - gene - - - Su(mg)1-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060422 l(3)S127816 lethal (3) S127816 http://flybase.org/reports/FBgn0060422 gene - - - "1278/16, l(3)S127816" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0052766 CR32766 - http://flybase.org/reports/FBgn0052766 non_protein_coding_gene - - - CR32766 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050156 CG30156 - http://flybase.org/reports/FBgn0050156 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BcDNA:AT02529, BEST:GH05253, CG30156" "IPR001623:DnaJ domain, IPR015399:Domain of unknown function DUF1977, DnaJ-like" CG30156 11-Aug-17 DroID_v2017_08 "Drer\dnajb1a, Drer\dnajb2, Drer\dnajb4, Drer\dnajb9a, Drer\dnajb5, Drer\dnajc18, Drer\dnajb12b, Drer\dnajc22, Drer\dnajb14, Drer\dnajb12a, Drer\dnajb1b" "Scer\SIS1, Scer\HLJ1" "Cele\dnj-17, Cele\dnj-26, Cele\dnj-1" "Xtro\dnajc18, Xtro\dnajb13, Xtro\dnajb6, Xtro\dnajb2, Xtro\dnajb4, Xtro\dnajb12, Xtro\dnajb5, Xtro\dnajc22, Xtro\dnajb9, Xtro\dnajb14, Xtro\dnajb1" "Mmus\Dnajb12, Mmus\Dnajb4, Mmus\Dnajb5, Mmus\Dnajb7, Mmus\Dnajb9, Mmus\Dnajc21, Mmus\Dnajb6, Mmus\Dnajb8, Mmus\Dnajb3, Mmus\Dnajc22, Mmus\Dnajb1, Mmus\Dnajb2, Mmus\Dnajb14, Mmus\Dnajb13, Mmus\Dnajc18" "Hsap\DNAJB2, Hsap\DNAJB4, Hsap\DNAJC18, Hsap\DNAJB1, Hsap\DNAJB14, Hsap\DNAJB8, Hsap\DNAJB13, Hsap\DNAJB5, Hsap\DNAJB12, Hsap\DNAJC3, Hsap\DNAJB9, Hsap\DNAJC22, Hsap\DNAJB6, Hsap\DNAJB7" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0028115 l(3)S064301 lethal (3) S064301 http://flybase.org/reports/FBgn0028115 gene - - - l(3)S064301 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265555 12.82 - http://flybase.org/reports/FBgn0265555 gene - - - 12.82 - - 11-Aug-17 DroID_v2017_08 - - - - - - learning defective FBgn0062518 752 752 http://flybase.org/reports/FBgn0062518 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "#752, 752" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022377 Pt-13 Larval protein-13 http://flybase.org/reports/FBgn0022377 - gene - - - Pt-13 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031900 CG13786 - http://flybase.org/reports/FBgn0031900 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13786 - CG13786 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02289 I 0.427471052 2.009075973 0.751574122 -1.433574657 0.464278943 -0.241209096 FBgn0038476 kuk kugelkern http://flybase.org/reports/FBgn0038476 protein_coding_gene - nucleus organization ; GO:0006997 | inferred from mutant phenotype cell aging ; GO:0007569 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype nuclear inner membrane ; GO:0005637 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "kuk, CG5175, kuk/char, char, Kuk" - CG5175 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,short lived,gravitaxis defective,partially lethal - majority die" "nucleus | embryonic stage,nuclear envelope | embryonic stage 5P5), with Df(3R)C4,nucleus | embryonic stage 5P5), with Df(3R)C4,stage 6 embryo,epithelial cell,cell-cell junctionP5), with Df(3R)C4,longitudinal muscle,nucleus | adult stageMhc.Switch.PO,brain,nucleus | adult stageelav.Switch.PO,nucleus | adult stage,embryo,nucleus | embryonic stage 9,nucleus | gastrula stage,nucleus | blastoderm stage" FBgn0014328 l(3)ry73 lethal (3) ry73 http://flybase.org/reports/FBgn0014328 - gene - - - l(3)ry73 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050017 CG30017 - http://flybase.org/reports/FBgn0050017 protein_coding_gene - - - "BcDNA:HL05382, anon-WO0153538.29, anon-WO0153538.22, CG30017" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260067 2L1663 - http://flybase.org/reports/FBgn0260067 gene - - - 2L1663 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,viable" "embryonic/larval tracheal system,somatic clone" FBgn0010081 Rst(3)mth2 Resistance (3) malathion 2 http://flybase.org/reports/FBgn0010081 - gene - - - Rst(3)mth2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069969 CG40498 - http://flybase.org/reports/FBgn0069969 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG40498 - CG40498 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259739 CG42393 - http://flybase.org/reports/FBgn0259739 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42393 - CG42393 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267452 CR45802 - http://flybase.org/reports/FBgn0267452 non_protein_coding_gene - - - CR45802 - CR45802 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260867 CG42577 - http://flybase.org/reports/FBgn0260867 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42577 - CG42577 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085188 CG34159 - http://flybase.org/reports/FBgn0085188 protein_coding_gene - - - "CG34159, CG5739" IPR029428:Mapk-regulated corepressor-interacting protein CG34159 11-Aug-17 DroID_v2017_08 "Drer\fam195b, Drer\si:dkey-44g23.5" - - "Xtro\fam195a, Xtro\fam195b" "Mmus\Fam195b, Mmus\Fam195a" "Hsap\MCRIP2, Hsap\MCRIP1" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0067063 O18 O18 http://flybase.org/reports/FBgn0067063 gene - - - O18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,lethal,partially lethal - majority die" pigment cell FBgn0015035 Cyp4e3 Cytochrome P450-4e3 http://flybase.org/reports/FBgn0015035 - protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" lipid particle ; GO:0005811 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "cyp4e3, 4e3, P450, P-450, CG4105, Cyp4e3, Cyp4E3, CYP4E3" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG4105 11-Aug-17 DroID_v2017_08 "Drer\cyp26b1, Drer\cyp19a1b, Drer\cyp26c1, Drer\cyp3c4, Drer\cyp3c3, Drer\cyp46a1.1, Drer\cyp20a1, Drer\LOC100329425, Drer\cyp3c1, Drer\cyp4f3, Drer\cyp4v7, Drer\cyp46a1.4, Drer\cyp3a65, Drer\cyp3c2, Drer\cyp4t8, Drer\cyp4v8, Drer\cyp46a1.2, Drer\cyp26a1, Drer\cyp19a1a, Drer\cyp46a1.3" "Scer\ERG5, Scer\DIT2" "Cele\cyp-13A11, Cele\cyp-13A1, Cele\cyp-13A7, Cele\cyp-37B1, Cele\cyp-37A1, Cele\cyp-25A1, Cele\cyp-13A3, Cele\cyp-13A8, Cele\cyp-31A2, Cele\cyp-29A3, Cele\cyp-31A5, Cele\cyp-13A12, Cele\cyp-13A4, Cele\cyp-31A3, Cele\cyp-29A2, Cele\cyp-42A1, Cele\cyp-29A4, Cele\cyp-13A10, Cele\cyp-25A2, Cele\cyp-32B1, Cele\cyp-13A5, Cele\cyp-25A4, Cele\cyp-25A3, Cele\cyp-32A1" "Xtro\cyp26b1, Xtro\cyp19a1, Xtro\LOC100487918, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\cyp4v2, Xtro\cyp4f2, Xtro\cyp4b1, Xtro\cyp20a1, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\cyp26a1, Xtro\mgc108213" "Mmus\Cyp3a57, Mmus\Cyp4a12a, Mmus\Cyp3a16, Mmus\Cyp26a1, Mmus\Cyp3a11, Mmus\Cyp4f17, Mmus\Cyp3a25, Mmus\Cyp3a41b, Mmus\Cyp4a10, Mmus\Cyp19a1, Mmus\Cyp4a12b, Mmus\Cyp3a13, Mmus\Cyp4b1, Mmus\Cyp26b1, Mmus\Cyp4x1, Mmus\Cyp4f13, Mmus\Cyp4f15, Mmus\Cyp4f14, Mmus\Cyp4f18, Mmus\Cyp3a41a, Mmus\Cyp3a59, Mmus\Cyp26c1, Mmus\Cyp4f16, Mmus\Cyp20a1, Mmus\Cyp4a32, Mmus\Cyp4f40, Mmus\Cyp4v3, Mmus\Cyp4a29, Mmus\Cyp4a14, Mmus\Cyp4a31, Mmus\Cyp4f39, Mmus\Cyp46a1, Mmus\Cyp4a30b, Mmus\Cyp4f37, Mmus\Cyp3a44" "Hsap\CYP4B1, Hsap\CYP20A1, Hsap\CYP4Z1, Hsap\CYP4A22, Hsap\CYP26A1, Hsap\CYP3A7, Hsap\CYP4V2, Hsap\CYP3A43, Hsap\CYP26B1, Hsap\CYP19A1, Hsap\CYP3A5, Hsap\CYP4A11, Hsap\CYP3A4, Hsap\CYP26C1, Hsap\CYP4F11, Hsap\CYP4X1, Hsap\CYP4F22, Hsap\CYP4F8, Hsap\CYP46A1, Hsap\CYP4F12, Hsap\CYP4F2, Hsap\CYP4F3" "partially lethal - majority die,some die during pupal stage" DRSC03306 K 0.076295432 0.387234698 0.031325567 -0.111789663 2.446970416 1.177269737 FBgn0083068 CG33947 - http://flybase.org/reports/FBgn0083068 protein_coding_gene - - cytosol ; GO:0005829 | inferred from direct assay "CR33947, GH03576, BEST:GH03576, BcDNA:GH03576, CG33947, pncr011:3L" - CG33947 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028606 l(2)W19 lethal (2) W19 http://flybase.org/reports/FBgn0028606 gene - - - "l(2R)W19, l(2)W19" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266488 CG45087 - http://flybase.org/reports/FBgn0266488 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45087, Dromel_CG17725_FBtr0086701_pepck_uORF" - CG45087 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037573 CG7483 - http://flybase.org/reports/FBgn0037573 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 protein binding ; GO:0005515 | inferred from physical interaction with btz protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VJ87 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 "RNA splicing ; GO:0008380 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from genetic interaction with btz regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000619776 chromatin organization ; GO:0006325 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 exon-exon junction complex assembly ; GO:1903040 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay pole plasm ; GO:0045495 | inferred from direct assay "CG7483, DmRH28, eIF4A, l(3)84Fi, anon-WO0118547.364, EIF4AIII, 7483, eIF4A-III, eIF4AIII, eIF4A3" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7483 11-Aug-17 DroID_v2017_08 "Drer\eif4a2, Drer\eif4a1a, Drer\eif4a1b, Drer\eif4a3" "Scer\TIF1, Scer\TIF2, Scer\FAL1" "Cele\F57B9.3, Cele\F33D11.10, Cele\Y65B4A.6" "Xtro\eif4a2, Xtro\eif4a3, Xtro\eif4a1" "Mmus\Eif4a1, Mmus\Eif4a3, Mmus\Eif4a2, Mmus\Gm8994" "Hsap\EIF4A3, Hsap\EIF4A1, Hsap\EIF4A2" "lethal,germline clone,increased cell death" "cytoskeleton & oocyte | germ-line clone,nucleus & oocyte | germ-line clone,oocyte associated follicle cell,germline clone" DRSC26402 EK -0.76018031 -0.259375491 -0.782895709 -2.002493802 -2.276678911 -3.853109736 FBgn0259709 CG42363 - http://flybase.org/reports/FBgn0259709 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15675, CG42363" - CG42363 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032123 Oatp30B Organic anion transporting polypeptide 30B http://flybase.org/reports/FBgn0032123 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from direct assay active transmembrane transporter activity ; GO:0022804 | inferred from sequence or structural similarity with Oatp58Db transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with Oatp58Db organic substance transport ; GO:0071702 | inferred from direct assay organic substance transport ; GO:0071702 | inferred from sequence or structural similarity with Oatp58Db basolateral plasma membrane ; GO:0016323 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Oatp58Db "CG3811, oatp 30B, Oatp30B, oatp30B" "IPR020846:Major facilitator superfamily domain, IPR004156:Organic anion transporter polypeptide OATP, IPR002350:Kazal domain" CG3811 11-Aug-17 DroID_v2017_08 "Drer\slco1f4, Drer\LOC100536648, Drer\slco1c1, Drer\LOC101883455, Drer\slco1f2, Drer\slco3a1, Drer\slco1f3, Drer\slco5a1, Drer\slco2b1, Drer\LOC570448, Drer\slco4a1" - "Cele\Y70G10A.3, Cele\F47E1.2, Cele\F53B1.8" "Xtro\slco5a1, Xtro\slco4c1, Xtro\slco1b3, Xtro\slco2a1, Xtro\slco4a1, Xtro\slco3a1" "Mmus\Slco5a1, Mmus\Slco1a4, Mmus\Gm5724, Mmus\Slco1a6, Mmus\Slco4c1, Mmus\Gm6614, Mmus\Slco2a1, Mmus\Slco1b2, Mmus\Slco1a1, Mmus\Slco2b1, Mmus\Slco6d1, Mmus\Slco1c1, Mmus\Slco1a5, Mmus\Slco4a1, Mmus\Slco6c1, Mmus\Slco3a1" "Hsap\SLCO4A1, Hsap\SLCO2B1, Hsap\SLCO4C1, Hsap\SLCO6A1, Hsap\SLCO5A1, Hsap\SLCO1B3, Hsap\SLCO1B1, Hsap\SLCO3A1, Hsap\SLCO2A1, Hsap\SLCO1B7, Hsap\SLCO1C1, Hsap\SLCO1A2" "viable,fertile,visible,planar polarity defective" trichogen cell FBgn0019960 Mitofilin Mitofilin http://flybase.org/reports/FBgn0019960 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q16891 "CG6455, CG 6455, Mitofilin" IPR019133:Mitochondrial inner membrane protein Mitofilin CG6455 11-Aug-17 DroID_v2017_08 Drer\immt Scer\MIC60 "Cele\immt-1, Cele\F36D4.6, Cele\immt-2" Xtro\immt Mmus\Immt Hsap\IMMT "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0028538 Sec71 Secretory 71 http://flybase.org/reports/FBgn0028538 protein_coding_gene ARF guanyl-nucleotide exchange factor activity ; GO:0005086 | inferred from sequence or structural similarity ARF guanyl-nucleotide exchange factor activity ; GO:0005086 | inferred from biological aspect of ancestor with PANTHER:PTN000070561 protein binding ; GO:0005515 | inferred from physical interaction with Arl1 regulation of ARF protein signal transduction ; GO:0032012 | inferred from electronic annotation with InterPro:IPR000904 regulation of ARF protein signal transduction ; GO:0032012 | inferred by curator from GO:0005086 vesicle-mediated transport ; GO:0016192 | inferred from biological aspect of ancestor with PANTHER:PTN000070561 trans-Golgi network ; GO:0005802 | inferred from direct assay "BIG1, BG:DS00797.7, CG7578, Sec71, sec71" "IPR000904:Sec7 domain, IPR015403:Sec7, C-terminal, IPR016024:Armadillo-type fold, IPR032691:Guanine nucleotide exchange factor, N-terminal, IPR023394:Sec7 domain, alpha orthogonal bundle, IPR011989:Armadillo-like helical, IPR032629:Mon2, dimerisation and cyclophilin-binding domain" CG7578 11-Aug-17 DroID_v2017_08 "Drer\arfgef1, Drer\mon2, Drer\arfgef2" "Scer\SEC7, Scer\SYT1, Scer\YEL1" Cele\agef-1 "Xtro\fbxo8, Xtro\mon2, Xtro\arfgef2, Xtro\arfgef1" "Mmus\Arfgef2, Mmus\Arfgef1, Mmus\Fbxo8, Mmus\Mon2" "Hsap\ARFGEF2, Hsap\FBXO8, Hsap\ARFGEF1, Hsap\MON2" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC01893 I 1.728272202 0.876243531 1.280913621 -0.6216505 0.831588109 0.510418398 FBgn0004929 A-p Abnormal abdomen polygenic http://flybase.org/reports/FBgn0004929 - gene - - - "Asy, AA, A-p" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069214 gsu goldstaub http://flybase.org/reports/FBgn0069214 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gsu - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic/first instar larval cuticle,germline clone,maternal effect,egg,pre-blastoderm embryo" FBgn0010106 ctw cut wing http://flybase.org/reports/FBgn0010106 - gene - - - ctw - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263888 l(3)D24 - http://flybase.org/reports/FBgn0263888 gene - - - l(3)D24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0022744 anon-J7 anon-J7 http://flybase.org/reports/FBgn0022744 - gene - - - "J7, anon-J7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052654 Sec16 Secretory 16 http://flybase.org/reports/FBgn0052654 protein_coding_gene Ras GTPase binding ; GO:0017016 | inferred from physical interaction with Sar1 protein localization to endoplasmic reticulum exit site ; GO:0070973 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype regulation of COPII vesicle coating ; GO:0003400 | inferred from mutant phenotype positive regulation of protein exit from endoplasmic reticulum ; GO:0070863 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from direct assay endoplasmic reticulum exit site ; GO:0070971 | inferred from direct assay "CG2551, CG18079, BcDNA:RE70141, dSec16, sec26, CG32654, Sec16, dsec16, sec16" "IPR024298:Ancestral coatomer element 1, Sec16/Sec31, IPR024880:COPII coat assembly protein, Sec16, IPR011990:Tetratricopeptide-like helical domain" CG32654 11-Aug-17 DroID_v2017_08 "Drer\sec16a, Drer\sec16b" Scer\SEC16 "Cele\F13B9.1, Cele\sec-16" - "Mmus\Prrc2b, Mmus\Sec16a, Mmus\Sec16b" "Hsap\SEC16B, Hsap\SEC16A" viable FBgn0265662 CR44469 - http://flybase.org/reports/FBgn0265662 non_protein_coding_gene - - - "lincRNA.932, CR44469" - CR44469 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267161 CR45601 - http://flybase.org/reports/FBgn0267161 non_protein_coding_gene - - - CR45601 - CR45601 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065907 l(2)SH0190 lethal (2) SH0190 http://flybase.org/reports/FBgn0065907 gene - - - "l(2)SH0190, l(2)SH2 0190" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260722 CR42549 - http://flybase.org/reports/FBgn0260722 non_protein_coding_gene - - - CR42549 - CR42549 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267139 CR45579 - http://flybase.org/reports/FBgn0267139 non_protein_coding_gene - - - "lincRNA.749, CR45579" - CR45579 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030336 CG1578 - http://flybase.org/reports/FBgn0030336 protein_coding_gene - - - CG1578 "IPR002761:Diphthamide synthase domain, IPR006175:YjgF/YER057c/UK114 family, IPR013813:Endoribonuclease L-PSP/chorismate mutase-like, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR030662:Diphthine--ammonia ligase/Uncharacterised protein MJ0570" CG1578 11-Aug-17 DroID_v2017_08 "Drer\dph6, Drer\hrsp12" "Scer\MMF1, Scer\HMF1, Scer\DPH6" Cele\E01A2.5 Xtro\dph6 "Mmus\Rida, Mmus\Dph6" "Hsap\RIDA, Hsap\DPH6" "visible,partially lethal - majority die,some die during pupal stage,viable" trichogen cell DRSC19729 I 1.698509628 1.070807487 0.401884905 -0.256272057 -0.236248209 0.260020972 FBgn0034023 Ir52a Ionotropic receptor 52a http://flybase.org/reports/FBgn0034023 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir52a, DmelIR52a, CG12960, IR52a" - CG12960 11-Aug-17 DroID_v2017_08 - - Cele\glr-7 - - - viable FBgn0065206 l(2)SH2279 lethal (2) SH2279 http://flybase.org/reports/FBgn0065206 gene - - - "l(2)SH2279, l(2)SH2 2279" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058164 CG40164 - http://flybase.org/reports/FBgn0058164 protein_coding_gene - - - CG40164 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265379 CR44320 - http://flybase.org/reports/FBgn0265379 non_protein_coding_gene - - - "CR44320, lincRNA.859" - CR44320 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050345 CG30345 - http://flybase.org/reports/FBgn0050345 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR005829 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701" CG30345 "IPR011701:Major facilitator superfamily, IPR005829:Sugar transporter, conserved site, IPR020846:Major facilitator superfamily domain" CG30345 11-Aug-17 DroID_v2017_08 "Drer\slc46a3, Drer\zgc:174356, Drer\si:dkey-5g14.1, Drer\LOC100002406, Drer\slc46a1, Drer\si:ch211-262i1.4" Scer\YJL163C "Cele\Y4C6B.5, Cele\C46C11.2, Cele\F40F9.5, Cele\Y43F8A.5" "Xtro\slc46a2, Xtro\slc46a1" "Mmus\Slc46a3, Mmus\Slc46a1, Mmus\Slc46a2" "Hsap\SLC46A2, Hsap\SLC46A3, Hsap\SLC46A1" "viable,fertile" FBgn0265955 CR44742 - http://flybase.org/reports/FBgn0265955 non_protein_coding_gene - - - "lincRNA.44, CR44742" - CR44742 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264303 CG43781 - http://flybase.org/reports/FBgn0264303 protein_coding_gene - - - "CG43781, CG8600" - CG43781 11-Aug-17 DroID_v2017_08 - - - - - - "fertile,viable" FBgn0004792 sat satin http://flybase.org/reports/FBgn0004792 FBgn0000998 gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "fs(2)SC46, sat" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0003966 vac vacuolated http://flybase.org/reports/FBgn0003966 - gene - - - vac - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" wing FBgn0038672 CG6005 - http://flybase.org/reports/FBgn0038672 protein_coding_gene - wound healing ; GO:0042060 | inferred from mutant phenotype - CG6005 - CG6005 11-Aug-17 DroID_v2017_08 Drer\wdr91 - Cele\sorf-1 Xtro\wdr91 Mmus\Wdr91 Hsap\WDR91 viable FBgn0060903 l(3)S043925b lethal (3) S043925b http://flybase.org/reports/FBgn0060903 gene - - - "0439/25, l(3)S043925b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010527 l(2)03050 lethal (2) 03050 http://flybase.net/reports/FBgn0010527.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive,partially,rescuable maternal effect" embryonic/first instar larval cuticle FBgn0026340 Su(tor)2-187-2 Su(tor)2-187-2 http://flybase.org/reports/FBgn0026340 - gene - - - Su(tor)2-187-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038432 CG14883 - http://flybase.org/reports/FBgn0038432 protein_coding_gene glycerophosphodiester phosphodiesterase activity ; GO:0008889 | inferred from electronic annotation with InterPro:IPR004129 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR017946 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - CG14883 "IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR004129:Glycerophosphoryl diester phosphodiesterase" CG14883 11-Aug-17 DroID_v2017_08 "Drer\gdpd5a, Drer\gdpd3b, Drer\gde1, Drer\gdpd2, Drer\gdpd4b, Drer\gdpd5b, Drer\gdpd3a, Drer\gdpd1, Drer\gdpd4a" Scer\PGC1 "Cele\ZC155.4, Cele\T12B3.3, Cele\T22G5.1, Cele\T09B9.3" "Xtro\gdpd5, Xtro\gdpd1, Xtro\gde1, Xtro\LOC100491166" "Mmus\Gdpd3, Mmus\Gdpd4, Mmus\Gdpd2, Mmus\Gdpd1, Mmus\Gdpd5, Mmus\Gde1" "Hsap\GDPD1, Hsap\GDPD5, Hsap\GDPD4, Hsap\GDE1, Hsap\GDPD2, Hsap\GDPD3" viable FBgn0266398 CR45038 - http://flybase.org/reports/FBgn0266398 non_protein_coding_gene - - - CR45038 - CR45038 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069184 mcl(2)Z0198 mcl(2)Z0198 http://flybase.org/reports/FBgn0069184 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z0198 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0037241 CG14646 - http://flybase.org/reports/FBgn0037241 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:25137 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:25137 "anon-WO0118547.373, CG14646" IPR018801:Putative transmembrane protein precursor CG14646 11-Aug-17 DroID_v2017_08 Drer\tmem129 - Cele\C34F6.7 Xtro\tmem129 Mmus\Tmem129 Hsap\TMEM129 "viable,fertile" FBgn0023223 E(Egfr)C12 Enhancer of Egfr C12 http://flybase.org/reports/FBgn0023223 - gene - - - E(Egfr)C12 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019904 anon-14Bf anon-14Bf http://flybase.org/reports/FBgn0019904 - gene - - - "ORF, anon-14Bf" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260061 2L2816 - http://flybase.org/reports/FBgn0260061 gene - - - 2L2816 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0260586 2L2677 - http://flybase.org/reports/FBgn0260586 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2677 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0010360 UVhs UV and heat shock response http://flybase.org/reports/FBgn0010360 - gene - - - UVhs - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266394 CR45034 - http://flybase.org/reports/FBgn0266394 non_protein_coding_gene - - - CR45034 - CR45034 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031207 CG13356 - http://flybase.org/reports/FBgn0031207 protein_coding_gene - - - CG13356 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261849 CG42781 - http://flybase.org/reports/FBgn0261849 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42781, MIP22495" - CG42781 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004079 Ars-region14 Autonomous replicating sequence region 14 http://flybase.org/reports/FBgn0004079 - region - - - "Ars-region14, Ars14" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034219 mthl4 methuselah-like 4 http://flybase.org/reports/FBgn0034219 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "methuselah-like 4, mthl4, CG6536, anon-WO0170980.56, anon-WO0170980.55" "IPR017981:GPCR, family 2-like, IPR000832:GPCR, family 2, secretin-like, IPR010596:Methuselah, N-terminal domain, IPR023311:Methuselah ectodomain, domain 2" CG6536 11-Aug-17 DroID_v2017_08 "Drer\fbn2b, Drer\adgrf6, Drer\LOC101884341, Drer\adgrg1, Drer\adgrf3a, Drer\LOC101886975, Drer\LOC100537181, Drer\adgrd2, Drer\adgre10, Drer\adgre14, Drer\adgrl1a, Drer\LOC100538279, Drer\fbn2a, Drer\adgrl2a, Drer\adgrg11, Drer\adgrg4a, Drer\adgre5b.3, Drer\adgrg3, Drer\adgrl4, Drer\LOC100535070, Drer\adgrf11, Drer\adgrl3.1, Drer\adgrg2a, Drer\adgrg6" - "Cele\lat-2, Cele\mth-2" "Xtro\adgrd1, Xtro\adgre5, Xtro\adgrf1, Xtro\gpr157, Xtro\adgrl1, Xtro\adgrf3, Xtro\adgrg1, Xtro\adgrv1" "Mmus\Adgrf5, Mmus\Adgrl4, Mmus\Adgre4, Mmus\Adgrf2, Mmus\Adgrg6, Mmus\Adgrg5, Mmus\Adgrd1, Mmus\Adgrf1, Mmus\Adgre5, Mmus\Adgrg7, Mmus\Adgrl1, Mmus\Adgrg1, Mmus\Adgrf4, Mmus\Adgrf3, Mmus\Adgrg3, Mmus\Adgre1, Mmus\Adgrl2, Mmus\Adgrl3, Mmus\Adgrg2, Mmus\Adgrg4" "Hsap\ADGRE2, Hsap\ADGRF1, Hsap\ADGRG3, Hsap\ADGRL4, Hsap\ADGRL3, Hsap\ADGRL2, Hsap\ADGRE5, Hsap\ADGRG7, Hsap\ADGRG5, Hsap\ADGRF5, Hsap\ADGRF3, Hsap\FBN3, Hsap\ADGRG1, Hsap\ADGRE1, Hsap\ADGRD2, Hsap\ADGRG6, Hsap\ADGRE3, Hsap\ADGRF2, Hsap\ADGRF4, Hsap\ADGRL1, Hsap\ADGRD1, Hsap\ADGRG4, Hsap\ADGRG2" FBgn0053317 CR33317 - http://flybase.org/reports/FBgn0053317 pseudogene_attribute - - - "CG18078, cg18092, CG18092, CR33317, CG33317" - CR33317 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052227 gogo golden goal http://flybase.org/reports/FBgn0052227 protein_coding_gene receptor activity ; GO:0004872 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CT33316, CG13817, CG13815, gogo, Gogo, CG32227" "IPR000859:CUB domain, IPR000884:Thrombospondin type-1 (TSP1) repeat" CG32227 11-Aug-17 DroID_v2017_08 "Drer\ism2a, Drer\ism1, Drer\ism2b" - Cele\F09F9.4 - Mmus\Ism1 Hsap\ISM1 "neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,somatic clone" "photoreceptor cell R8,medulla layer M1,transmedullary neuron Tm20,trichogen cell,mesothoracic tergum,medulla,somatic clone,lamina,photoreceptor cell R7,multidendritic neuron,photoreceptor cell" FBgn0026609 Abl::Hsap\ABL1::Hsap\BCR Abl::Hsap\ABL1::Hsap\BCR http://flybase.org/reports/FBgn0026609 FBgn0024503 engineered_fusion_gene - - - "Bcr-Abl, Bcr/Abl, Abl::Hsap\BCR, Abl::Hsap\ABL1::Hsap\BCR, BcrAbl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,neuroanatomy defective" "presumptive embryonic/larval central nervous system,ventral nerve cord commissure,longitudinal connective,lens,eye,ommatidium,eye photoreceptor cell,rhabdomerehs.2sev,interommatidial bristle,secondary pigment cell,tertiary pigment cell,ventral adult lateral neuron & axonP2.4.Pdf,midline crossing tract | embryonic stage 16,ventral nerve cord commissure | embryonic stage 16,longitudinal connective | embryonic stage 16,midline crossing tract,ectopic,longitudinal connective | embryonic stage" FBgn0267637 CR45975 - http://flybase.org/reports/FBgn0267637 non_protein_coding_gene - - - CR45975 - CR45975 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005283 M(3)S35 Minute (3) S35 http://flybase.org/reports/FBgn0005283 - gene - - - "M(3)f, M(3)S35" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible" macrochaeta FBgn0261934 dikar dikar http://flybase.org/reports/FBgn0261934 protein_coding_gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG32394, CG42799, CG10115, CG32393, dikar" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001487:Bromodomain" CG42799 11-Aug-17 DroID_v2017_08 "Drer\kat2b, Drer\cecr2, Drer\kat2a" "Scer\SPT7, Scer\GCN5" Cele\nurf-1 "Xtro\cecr2, Xtro\kat2a, Xtro\kat2b" "Mmus\Kat2b, Mmus\Kat2a, Mmus\Cecr2" "Hsap\KAT2A, Hsap\KAT2B, Hsap\CECR2" """DRSC22261, DRSC09699"" " IE FBgn0052262 CG32262 - http://flybase.org/reports/FBgn0052262 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 "CG10854, CG32262" IPR007248:Mpv17/PMP22 CG32262 11-Aug-17 DroID_v2017_08 "Drer\mpv17l2, Drer\mpv17, Drer\pxmp2, Drer\si:ch211-120k19.1" "Scer\SYM1, Scer\YOR292C" "Cele\ZK470.1, Cele\T18D3.9" "Xtro\pxmp2, Xtro\mpv17l2, Xtro\LOC100497159" "Mmus\Mpv17l, Mmus\Pxmp2, Mmus\Mpv17, Mmus\Mpv17l2" "Hsap\PXMP2, Hsap\MPV17L2, Hsap\MPV17L, Hsap\MPV17" "partially lethal - majority die,some die during pupal stage" FBgn0047000 CG33946 - http://flybase.org/reports/FBgn0047000 protein_coding_gene - - - "CR33946, BcDNA:RH62830, pncr008:3L, CG33946" - CG33946 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031127 CG1835 - http://flybase.org/reports/FBgn0031127 protein_coding_gene - - - "BcDNA:GH25431, anon-WO0140519.219, CG1835" - CG1835 11-Aug-17 DroID_v2017_08 - - Cele\spe-38 - - - viable FBgn0051475 CG31475 - http://flybase.org/reports/FBgn0051475 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR027240" neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - "CG14281, CG3768, CG31475" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG31475 11-Aug-17 DroID_v2017_08 Drer\sdf4 - Cele\C56C10.9 Xtro\sdf4 Mmus\Sdf4 Hsap\SDF4 FBgn0040669 CG14602 - http://flybase.org/reports/FBgn0040669 protein_coding_gene - - - CG14602 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060592 l(3)S093008 lethal (3) S093008 http://flybase.org/reports/FBgn0060592 gene - - - "0930/08, l(3)S093008" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0000425 DebA Developmental embryonic A http://flybase.org/reports/FBgn0000425 - protein_coding_gene - - - "Deb-A, Deb, CG17967, DebA" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000158 bam bag of marbles http://flybase.org/reports/FBgn0000158 - protein_coding_gene "mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from direct assay" fusome organization ; GO:0045478 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype spermatogonial cell division ; GO:0007284 | inferred from mutant phenotype cystoblast division ; GO:0007282 | traceable author statement germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from mutant phenotype cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype male meiosis ; GO:0007140 | traceable author statement germ-line stem cell population maintenance ; GO:0030718 | inferred from direct assay spermatogenesis ; GO:0007283 | traceable author statement female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from mutant phenotype gamete generation ; GO:0007276 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype male germline stem cell symmetric division ; GO:0098730 | inferred from mutant phenotype cell fate specification ; GO:0001708 | traceable author statement female germ-line cyst formation ; GO:0048135 | traceable author statement germ cell development ; GO:0007281 | traceable author statement cystoblast division ; GO:0007282 | inferred from mutant phenotype cytoplasm ; GO:0005737 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay spectrosome ; GO:0045170 | inferred from direct assay fusome ; GO:0045169 | traceable author statement fusome ; GO:0045169 | inferred from direct assay "bam, BamC, BamF, Bam, ham, CG10422, alpha, fs(3)neo61, BAM, Bam-C" - CG10422 11-Aug-17 DroID_v2017_08 - - - - - - " spermatogenesis && adult stage , adult stage && oogenesis stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage S10 " " testis

, cystoblast

, ovary

, nurse cell

, centripetally migrating follicle cell

, cystocyte

" "female sterile,recessive,male semi-sterile,viable,fertile,male sterile,tumorigenic,increased cell number,wild-type,decreased cell number,heat sensitive,hyperplasia,cytokinesis defective,cell cycle defective,female fertile,poor" "ovary,ovariole,spermatid,spermatocyte cyst,spermatozoon,sperm individualization complex,egg chamber,germline cell,female,fusome,testis,spermatogonial cyst,male,hub cell,male germline stem cell,primary gonial cell,female germline stem cell,heat sensitive,germline cyst,germarium,ectopic,germarium & germ cell,cyst progenitor cell,male limited,spermatogonium,germline stem cell,female germline cell,germline clone,supernumerary,germarium cap cell,stem cell fusome,escort cell,escort stem cell,nurse cell fusome,cystoblast,spermatocyte" FBgn0267212 CR45652 - http://flybase.org/reports/FBgn0267212 non_protein_coding_gene - - - CR45652 - CR45652 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085647 CG41428 - http://flybase.org/reports/FBgn0085647 protein_coding_gene - - - CG41428 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051460 CG31460 - http://flybase.org/reports/FBgn0051460 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG11745, BcDNA:RE67710, CG31460" IPR018614:Keratinocyte-associated protein 2 CG31460 11-Aug-17 DroID_v2017_08 Drer\krtcap2 - - - Mmus\Krtcap2 Hsap\KRTCAP2 "viable,fertile" FBgn0035144 Kah Kahuli http://flybase.org/reports/FBgn0035144 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nuclear chromosome ; GO:0000228 | inferred from direct assay "CG17181, Kah, kah" IPR013087:Zinc finger C2H2-type CG17181 11-Aug-17 DroID_v2017_08 "Drer\wu:fe17e08, Drer\zbtb24, Drer\LOC100330167, Drer\LOC101883594, Drer\si:ch211-276c2.4, Drer\snai1b, Drer\LOC103909987, Drer\LOC108179164, Drer\si:dkey-261j4.3, Drer\im:7141269, Drer\LOC100538142, Drer\si:dkey-261j4.4, Drer\si:dkey-262g12.3, Drer\scrt2, Drer\snai1a, Drer\si:ch211-155e24.3, Drer\LOC560148, Drer\LOC103911016, Drer\snai2, Drer\LOC799968, Drer\si:ch211-198a12.6, Drer\scrt1b, Drer\si:ch211-241b2.4, Drer\si:ch211-222k6.2, Drer\LOC100537317, Drer\scrt1a, Drer\snai3, Drer\zgc:112998, Drer\si:dkey-261j4.5, Drer\LOC101883230, Drer\si:ch73-299h12.9, Drer\zgc:171673, Drer\LOC100333031, Drer\si:dkey-34m19.3, Drer\zgc:165514, Drer\drl, Drer\si:ch73-40a17.4" Scer\AZF1 "Cele\che-1, Cele\scrt-1, Cele\Y56A3A.28, Cele\ces-1, Cele\snai-1" "Xtro\snai2, Xtro\snai1" "Mmus\Snai3, Mmus\Scrt1, Mmus\Zfp637, Mmus\Snai1, Mmus\Zfp853, Mmus\Zbtb24, Mmus\Snai2, Mmus\Scrt2" "Hsap\SNAI1, Hsap\SNAI3, Hsap\ZNF853, Hsap\SNAI2, Hsap\ZNF32, Hsap\SCRT2, Hsap\SCRT1" "visible,viable,fertile" "eye,adult thorax,adult cuticle,chaeta" FBgn0266205 CR44900 - http://flybase.org/reports/FBgn0266205 non_protein_coding_gene - - - CR44900 - CR44900 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050509 tRNA:Ile-AAT-1-8 transfer RNA:Isoleucine-AAT 1-8 http://flybase.org/reports/FBgn0050509 tRNA_gene AUU codon-amino acid adaptor activity ; GO:0033433 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033433 cytosol ; GO:0005829 | inferred by curator from GO:0033433 "CR30509, AE002787.trna42-IleAAT, tRNA:I:AAT:AE002787-g, CR30243, chr2R.trna24-IleAAT, tRNA-Ile[AAU], tRNA-Ile-AAT-1-8, tRNA:Ile-AAT-1-8, tRNA:CR30509, AUU" - CR30509 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086169 nkd::Btau\recoverin - http://flybase.org/reports/FBgn0086169 engineered_fusion_gene - - - nkd::Btau\recoverin - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001044 fs(3)HO115 female sterile (3) HO115 http://flybase.org/reports/FBgn0001044 - gene - - - "fs(3)115A, fs(3)HO115" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile oocyte FBgn0044415 Scim12 Sensitized chromosome inheritance modifier 12 http://flybase.org/reports/FBgn0044415 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay Scim12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant,mitotic cell cycle defective" "mitosis & nuclear chromosome,metaphase & condensed nuclear chromosome,nuclear chromosome" FBgn0003531 stmB stambha B http://flybase.org/reports/FBgn0003531 - gene - - - "stm-B, stmB" - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,recessive,heat sensitive" FBgn0024761 EC69 EC69 http://flybase.org/reports/FBgn0024761 - gene - - - EC69 - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,female,non-enhancer of variegation,male" FBgn0060892 l(3)S044612 lethal (3) S044612 http://flybase.org/reports/FBgn0060892 gene - - - "0446/12, l(3)S044612" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0264949 CR44118 - http://flybase.org/reports/FBgn0264949 non_protein_coding_gene - - - CR44118 - CR44118 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083986 CG34150 - http://flybase.org/reports/FBgn0083986 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34150 IPR008011:Complex 1 LYR protein CG34150 11-Aug-17 DroID_v2017_08 Drer\lyrm7 Scer\MZM1 - Xtro\lyrm7 Mmus\Lyrm7 Hsap\LYRM7 FBgn0031177 CG14582 - http://flybase.org/reports/FBgn0031177 protein_coding_gene - - - CG14582 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023411 Ars-region42 Autonomous replicating sequence region 42 http://flybase.org/reports/FBgn0023411 - region - - - "dARS42, Ars-region42, Ars42" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053221 CR33221 - http://flybase.org/reports/FBgn0053221 pseudogene_attribute - - - "CG12260, CG33221, CR33221" - CR33221 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259112 CR42254 - http://flybase.org/reports/FBgn0259112 non_protein_coding_gene - - - "CG42254, CR42254, CR30478, CG12854, mdcds_11485" - CR42254 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085777 CR40959 - http://flybase.org/reports/FBgn0085777 rRNA_gene - - - CR40959 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001034 Fs(3)Far Farkas http://flybase.org/reports/FBgn0001034 - gene molecular_function ; GO:0003674 | no biological data available pronuclear fusion ; GO:0007344 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Far, Fs(3)Farkas, Fs(3)Sz8, Fs(3)Far" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "male pronucleus | maternal effect,female pronucleus | maternal effect" FBgn0031700 CG14022 - http://flybase.org/reports/FBgn0031700 protein_coding_gene acylphosphatase activity ; GO:0003998 | inferred from biological aspect of ancestor with PANTHER:PTN000003030 - - "BcDNA:RH62365, CG14022" "IPR001792:Acylphosphatase-like domain, IPR020456:Acylphosphatase" CG14022 11-Aug-17 DroID_v2017_08 "Drer\acyp1, Drer\acyp2" - - "Xtro\acyp2, Xtro\acyp1" "Mmus\Acyp1, Mmus\Acyp2" "Hsap\ACYP2, Hsap\ACYP1" "viable,body color defective" mesothoracic tergum FBgn0005312 ms(3)10R male sterile (3) 10R http://flybase.org/reports/FBgn0005312 - gene - - - ms(3)10R - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,female sterile" "seminal vesicle,spermatid,spermatid & nucleus,spermatid axoneme,Nebenkern derivative,acrosomal granule" FBgn0016625 E(gl)2A Enhancer of glass 2A http://flybase.org/reports/FBgn0016625 - gene - - - E(gl)2A - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029524 CG3176 - http://flybase.org/reports/FBgn0029524 protein_coding_gene - - - "BcDNA:RH59219, CG3176" IPR022773:Siva CG3176 11-Aug-17 DroID_v2017_08 Drer\siva1 - - Xtro\siva1 Mmus\Siva1 Hsap\SIVA1 DRSC18288 I 0.283302752 -2.077113422 -0.489477945 0.35674044 0.563331233 -0.477990687 FBgn0010909 msn misshapen http://flybase.org/reports/FBgn0010909 "FBgn0010797, FBgn0024520, FBgn0035351" protein_coding_gene "protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 JUN kinase kinase kinase kinase activity ; GO:0042656 | traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement MAP kinase kinase kinase kinase activity ; GO:0008349 | inferred from sequence or structural similarity MAP kinase kinase kinase kinase activity ; GO:0008349 | non-traceable author statement" "regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype activation of MAPKKK activity ; GO:0000185 | non-traceable author statement response to wounding ; GO:0009611 | inferred from expression pattern JNK cascade ; GO:0007254 | non-traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with ninaC inferred from sequence or structural similarity with SGD:S000000072 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity dorsal closure ; GO:0007391 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype optic lobe placode development ; GO:0001748 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr JNK cascade ; GO:0007254 | inferred from sequence or structural similarity inferred from mutant phenotype inferred from genetic interaction with bsk inferred from genetic interaction with hep oogenesis ; GO:0048477 | non-traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement establishment of planar polarity ; GO:0001736 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype inferred from genetic interaction with bsk inferred from genetic interaction with hep photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype nuclear migration ; GO:0007097 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype" contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "MSN, Msn, DMSN, NIK, CG16973, MESR5, l(3)6286, msm, 6286, l(3)06946, l(3)j1E2, l(3)03349, Nik, msn, HGK, JNKKKK" "IPR000719:Protein kinase domain, IPR001180:Citron homology (CNH) domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR015943:WD40/YVTN repeat-like-containing domain" CG16973 11-Aug-17 DroID_v2017_08 "Drer\mink1, Drer\tnikb, Drer\si:zfos-2326c3.2, Drer\myo3b, Drer\tnika, Drer\map4k4" "Scer\SPS1, Scer\KIC1" Cele\mig-15 "Xtro\kit, Xtro\LOC100489062, Xtro\nrk, Xtro\myo3b, Xtro\LOC100494069, Xtro\sptbn1, Xtro\myo3a, Xtro\tnik" "Mmus\Mink1, Mmus\Myo3b, Mmus\Tnik, Mmus\Myo3a, Mmus\Nrk, Mmus\Map4k4" "Hsap\MYO3B, Hsap\MINK1, Hsap\MYO3A, Hsap\TNIK, Hsap\MAP4K4, Hsap\NRK" "lethal,partially lethal - majority die,recessive,neuroanatomy defective,maternal effect,poor,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,visible,planar polarity defective,somatic clone,wild-type,chemical sensitive" "lamina,photoreceptor cell | precursor & nucleusunspecified, msnDN.UAS,eye photoreceptor cell & axon,medulla,eye photoreceptor cell & growth cone,photoreceptor cell & axon,lamina plexus,embryonic/first instar larval cuticle,maternal effect,adult thorax,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,frontal ganglion,stomodeal nerve,microchaeta & scutumap-md544,wing hair,eye,ommatidium,rhabdomerehs.2sev,eye photoreceptor cell,ommatidial precursor cluster,eye photoreceptor cell & axonGMR.PF,photoreceptor cell R1 & axonGMR.PF,photoreceptor cell R2 & axonGMR.PF,photoreceptor cell R3 & axonGMR.PF,photoreceptor cell R4 & axonGMR.PF,photoreceptor cell R5 & axonGMR.PF,photoreceptor cell R6 & axonGMR.PF,photoreceptor cell R7 & axonGMR.PF,photoreceptor cell R8 & axonGMR.PF,intersegmental nerve,embryonic/larval salivary gland,axon69B, msnP656A,P659A.UAS,photoreceptor & axon69B, msnP656A,P659A.UAS,eye disc,somatic clone,rhabdomere,photoreceptor cell R4,photoreceptor cell | precursor & nucleus | somatic clone,photoreceptor & axon | somatic clone,lamina neuropil,dorsal,eye photoreceptor cell & axon | somatic clone,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,egg,precursor,wing disc,germline clone,neuron,dorsal closure embryo,embryonic segment,filamentous actin | dorsal closure stage,follicle cell,actin filament | somatic clone,egg chamber,photoreceptor cell | precursor & nucleusunspecified, msn03349,photoreceptor cell | precursor & nucleusunspecified,myosin II complex | dorsal closure stagee22c,embryonic leading edge cell,filamentous actin | dorsal closure stagee22c,myosin II complex | dorsal closure stageLE,filamentous actin | dorsal closure stageLE,ventral furrow,axon69B, msn102,photoreceptor & axon69B, msn102" FBgn0003301 rut rutabaga http://flybase.org/reports/FBgn0003301 FBgn0044471 protein_coding_gene calcium- and calmodulin-responsive adenylate cyclase activity ; GO:0008294 | inferred from direct assay inferred from mutant phenotype adenylate cyclase activity ; GO:0004016 | traceable author statement adenylate cyclase activity ; GO:0004016 | non-traceable author statement calcium- and calmodulin-responsive adenylate cyclase activity ; GO:0008294 | traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "cAMP biosynthetic process ; GO:0006171 | inferred from electronic annotation with InterPro:IPR009398 response to heat ; GO:0009408 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | traceable author statement cAMP-mediated signaling ; GO:0019933 | non-traceable author statement grooming behavior ; GO:0007625 | non-traceable author statement learning or memory ; GO:0007611 | non-traceable author statement sleep ; GO:0030431 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from mutant phenotype regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype learning ; GO:0007612 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from direct assay behavioral response to ethanol ; GO:0048149 | traceable author statement axon extension ; GO:0048675 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | non-traceable author statement mating behavior ; GO:0007617 | traceable author statement olfactory learning ; GO:0008355 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype conditioned taste aversion ; GO:0001661 | inferred from mutant phenotype learning ; GO:0007612 | non-traceable author statement olfactory learning ; GO:0008355 | non-traceable author statement courtship behavior ; GO:0007619 | traceable author statement molting cycle, chitin-based cuticle ; GO:0007591 | inferred from genetic interaction with Itp-r83A behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype regulation of protein kinase A signaling ; GO:0010738 | inferred from mutant phenotype cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype cyclic nucleotide biosynthetic process ; GO:0009190 | inferred from direct assay short-term memory ; GO:0007614 | inferred from mutant phenotype cAMP biosynthetic process ; GO:0006171 | non-traceable author statement" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 membrane ; GO:0016020 | inferred from direct assay guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG9533, AC, Ac12F, EP1603, rut, Rut, Rut-AC, RUT" "IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR009398:Adenylate cyclase, conserved domain, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029787:Nucleotide cyclase, IPR032628:Adenylate cyclase, N-terminal" CG9533 11-Aug-17 DroID_v2017_08 "Drer\adcy5, Drer\adcy2b, Drer\adcy6a, Drer\adcy8, Drer\si:dkey-206f10.1, Drer\adcy3a, Drer\si:ch211-132f19.7, Drer\adcy6b, Drer\adcy1b, Drer\adcy2a, Drer\adcy1a, Drer\adcy7" - "Cele\acy-2, Cele\acy-4" "Xtro\adcy7, Xtro\adcy6, Xtro\adcy4, Xtro\adcy1, Xtro\dnajc27" "Mmus\Adcy5, Mmus\Adcy1, Mmus\Adcy6, Mmus\Adcy8, Mmus\Adcy2, Mmus\Adcy7, Mmus\Adcy4, Mmus\Adcy3" "Hsap\ADCY6, Hsap\ADCY4, Hsap\ADCY7, Hsap\ADCY8, Hsap\ADCY2, Hsap\ADCY1, Hsap\ADCY3, Hsap\ADCY5" " adult stage , larval stage " " adult brain

, adult mushroom body

, mushroom body

, subesophageal ganglion

, optic lobe

" adult stage " mushroom body beta-lobe

, mushroom body gamma-lobe

, pedunculus

, optic lobe

, calyx of mushroom body

, adult brain

, subesophageal ganglion

, mushroom body

" "memory defective,learning defective,semidominant,neurophysiology defective,recessive,chemical sensitive,immune response defective,visual behavior defective,optomotor response defective,smell perception defective,taste perception defective,starvation stress response defective,neuroanatomy defective,locomotor behavior defective,drug conditional,lethal - all die before end of larval stage,some die during larval stage,behavior defective,thermotaxis behavior defective,sleep defective,viable" "neuromuscular junction,adult brain,axon & motor neuron | conditional ts,multidendritic neuron,embryonic/larval neuromuscular junction,macrochaeta,intersegmental nerve,anterior fascicle & synapse,embryonic/larval somatic muscle,growth cone & embryonic neuron,cell body & giant fibers,central nervous system,dense body,synapse,calyx of adult mushroom body,RP3 neuron & synapse,RP3 neuron & synaptic vesicle,neuromuscular junction | larval stage,neuromuscular junction & abdominal 4 ventral longitudinal muscle 4 & larva,neuromuscular junction & abdominal 4 ventral longitudinal muscle 3 & larva,varicosity | third instar larval stage,axon | third instar larval stage,neuromuscular junction | third instar larval stage,NMJ bouton,aCC neuron,RP2 motor neuron,supernumerary,NMJ bouton | larval stage" DRSC22976 K 0.8915598 2.983827794 FBgn0039676 ppk20 pickpocket 20 http://flybase.org/reports/FBgn0039676 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 membrane ; GO:0016020 | inferred from sequence model with InterPro:IPR001873 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK20, CG7577, ppk20" IPR001873:Epithelial sodium channel CG7577 11-Aug-17 DroID_v2017_08 "Drer\asic2, Drer\asic4b, Drer\asic1c, Drer\asic1b, Drer\asic1a, Drer\asic4a" - "Cele\acd-1, Cele\delm-2, Cele\acd-4, Cele\delm-1, Cele\acd-2, Cele\flr-1" "Xtro\asic4, Xtro\scnn1g, Xtro\asic1, Xtro\asic5, Xtro\scnn1d, Xtro\scnn1b, Xtro\scnn1a" "Mmus\Asic5, Mmus\Scnn1b, Mmus\Scnn1g, Mmus\Asic4, Mmus\Scnn1a, Mmus\Asic1, Mmus\Asic2, Mmus\Asic3" "Hsap\ASIC2, Hsap\SCNN1G, Hsap\SCNN1D, Hsap\ASIC4, Hsap\SCNN1B, Hsap\SCNN1A, Hsap\ASIC1, Hsap\ASIC5, Hsap\ASIC3" "viable,lethal" FBgn0051845 CR31845 - http://flybase.org/reports/FBgn0051845 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31845, CR31845" - CR31845 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033929 Tfb1 Transcription factor B1 http://flybase.org/reports/FBgn0033929 protein_coding_gene "DNA-dependent ATPase activity ; GO:0008094 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000304482 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000304482 transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675" phosphorylation of RNA polymerase II C-terminal domain ; GO:0070816 | inferred from biological aspect of ancestor with PANTHER:PTN000304482 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000304482 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4655 inferred from sequence or structural similarity with SGD:S000002719 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000304482 response to UV ; GO:0009411 | inferred from mutant phenotype transcriptional open complex formation at RNA polymerase II promoter ; GO:0001113 | inferred from sequence or structural similarity with HGNC:4655 nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity with HGNC:4655 promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from sequence or structural similarity with HGNC:4655 transcription from RNA polymerase I promoter ; GO:0006360 | inferred from biological aspect of ancestor with PANTHER:PTN000304482 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:4655 inferred from sequence or structural similarity with SGD:S000002719 core TFIIH complex ; GO:0000439 | inferred from sequence or structural similarity with HGNC:4655 inferred from sequence or structural similarity with SGD:S000002719 holo TFIIH complex ; GO:0005675 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:4655 inferred from sequence or structural similarity with SGD:S000002719 core TFIIH complex ; GO:0000439 | inferred from biological aspect of ancestor with PANTHER:PTN000304482 "Tfb1, CG8151, TFB1, l(2)06949, Dmp62, l(2)06950, p62, TfBl" "IPR005607:BSD domain, IPR011993:PH domain-like, IPR013876:TFIIH p62 subunit, N-terminal, IPR027079:TFIIH subunit Tfb1/p62" CG8151 11-Aug-17 DroID_v2017_08 Drer\gtf2h1 Scer\TFB1 Cele\R02D3.3 Xtro\gtf2h1 Mmus\Gtf2h1 Hsap\GTF2H1 embryonic stage -- adult stage "lethal,recessive,radiation sensitive,dominant,conditional,visible,partially lethal - majority die,some die during pupal stage" "adult cuticle,conditional,trichogen cell,mesothoracic tergum" DRSC07082 I -1.682262925 0.794798871 -0.641031415 -0.04223141 0.510236888 0.156893115 FBgn0011046 l(3)AFA7 lethal (3) AFA7 http://flybase.org/reports/FBgn0011046 FBgn0005200 gene - - - l(3)AFA7 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0259324 C359 - http://flybase.org/reports/FBgn0259324 gene - - - C359 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing margin,chaeta" FBgn0259148 CG42263 - http://flybase.org/reports/FBgn0259148 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42263 - CG42263 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003577 su(sc)r "suppressor of scute, recessive" http://flybase.org/reports/FBgn0003577 - gene - - - "su(sc)r, su(sc)" - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile "wing,male" FBgn0020329 anon-6F7 anon-6F7 http://flybase.org/reports/FBgn0020329 - gene - - - "6F7, anon-6F7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026265 bao beatoangelico http://flybase.org/reports/FBgn0026265 - gene - - - bao - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0021786 l(3)02624 lethal (3) 02624 http://flybase.org/reports/FBgn0021786 - gene - - - "l(2)02624, l(3)02624" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0013943 E(var)3-201 E(var)3-201 http://flybase.org/reports/FBgn0013943 - gene - - - E(var)3-201 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001887 l(2)21Da lethal (2) 21Da http://flybase.org/reports/FBgn0001887 - gene - - - "l(2)neh-1, l(2)neh1, l(2)21Da" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065108 ppk16 pickpocket 16 http://flybase.org/reports/FBgn0065108 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG34059, PPK16, CG4110, ppk16" "IPR020903:Epithelial sodium channel, conserved site, IPR001873:Epithelial sodium channel" CG34059 11-Aug-17 DroID_v2017_08 "Drer\asic2, Drer\asic1a, Drer\asic4a, Drer\asic4b, Drer\asic1c, Drer\asic1b" - "Cele\acd-1, Cele\acd-4, Cele\acd-2, Cele\flr-1, Cele\delm-2, Cele\delm-1, Cele\acd-5" "Xtro\scnn1a, Xtro\scnn1g, Xtro\asic4, Xtro\asic5, Xtro\scnn1b, Xtro\scnn1d, Xtro\asic1" "Mmus\Scnn1a, Mmus\Asic1, Mmus\Asic2, Mmus\Scnn1g, Mmus\Scnn1b, Mmus\Asic5, Mmus\Asic4, Mmus\Asic3" "Hsap\SCNN1G, Hsap\ASIC2, Hsap\ASIC4, Hsap\ASIC1, Hsap\SCNN1D, Hsap\ASIC3, Hsap\SCNN1A, Hsap\SCNN1B, Hsap\ASIC5" "neurophysiology defective,viable" FBgn0033196 CG1358 - http://flybase.org/reports/FBgn0033196 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG1358 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG1358 11-Aug-17 DroID_v2017_08 "Drer\flvcr1, Drer\dirc2, Drer\flvcr2b, Drer\flvcr2a" - "Cele\B0416.5, Cele\C42C1.8, Cele\C09D4.1" "Xtro\flvcr1, Xtro\dirc2, Xtro\mfsd7, Xtro\flvcr2" "Mmus\Mfsd7a, Mmus\Mfsd7b, Mmus\Dirc2, Mmus\Mfsd7c" "Hsap\FLVCR2, Hsap\MFSD7, Hsap\FLVCR1, Hsap\DIRC2" "viable,locomotor rhythm defective" DRSC06405 E -0.696118612 -0.878601477 -0.306235294 -2.177564499 0.541026459 0.095443917 FBgn0039009 CG13842 - http://flybase.org/reports/FBgn0039009 protein_coding_gene - - - CG13842 IPR026700:Coiled-coil domain-containing protein 142 CG13842 11-Aug-17 DroID_v2017_08 Drer\ccdc142 - - - Mmus\Ccdc142 Hsap\CCDC142 viable FBgn0005483 l(1)ts1343 lethal (1) ts1343 http://flybase.org/reports/FBgn0005483 - gene - - - l(1)ts1343 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0010020 E(Dl)9P39.3 Enhancer of Delta 9P39.3 http://flybase.org/reports/FBgn0010020 - gene - - - E(Dl)9P39.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022132 l(2)k06402 lethal (2) k06402 http://flybase.net/reports/FBgn0022132.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0043587 EP595a EP595a http://flybase.org/reports/FBgn0043587 gene - - - "EP0595a, EP595a" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065215 l(2)SH2252 lethal (2) SH2252 http://flybase.org/reports/FBgn0065215 gene - - - "l(2)SH2252, l(2)SH2 2252" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043564 Su(hh)III Su(hh)III http://flybase.org/reports/FBgn0043564 gene - - - Su(hh)III - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0066338 nov novichok http://flybase.org/reports/FBgn0066338 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available nov - - 11-Aug-17 DroID_v2017_08 - - - - - - "learning defective,memory defective" FBgn0039165 CG6204 - http://flybase.org/reports/FBgn0039165 protein_coding_gene - - - "CG6204, GH20028p" IPR027417:P-loop containing nucleoside triphosphate hydrolase CG6204 11-Aug-17 DroID_v2017_08 Drer\znfx1 Scer\SEN1 "Cele\eri-7, Cele\ZK1067.2" "Xtro\znfx1.2, Xtro\znfx1" Mmus\Znfx1 Hsap\ZNFX1 viable DRSC15991 K 0.480711348 0.344115532 0.059433672 0.74330294 2.064624694 -0.040557557 FBgn0014056 Su(tor)2-4 Su(tor)2-4 http://flybase.org/reports/FBgn0014056 - gene - - - Su(tor)2-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye FBgn0005183 l(2)S7 lethal of Seto 7 http://flybase.org/reports/FBgn0005183 - gene - - - l(2)S7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "sterile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032188 CG13137 - http://flybase.org/reports/FBgn0032188 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13137 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat" CG13137 11-Aug-17 DroID_v2017_08 "Drer\glis3, Drer\glis2a, Drer\aaas, Drer\glis2b, Drer\LOC100333406" - - "Xtro\aaas, Xtro\glis2, Xtro\glis3" "Mmus\Glis1, Mmus\Glis2, Mmus\Aaas" "Hsap\AAAS, Hsap\GLIS1, Hsap\GLIS3, Hsap\GLIS2" "viable,body color defective" mesothoracic tergum FBgn0265750 CR44557 - http://flybase.org/reports/FBgn0265750 non_protein_coding_gene - - - CR44557 - CR44557 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052655 CG32655 - http://flybase.org/reports/FBgn0052655 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32655 - CG32655 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003117 pnr pannier http://flybase.org/reports/FBgn0003117 FBgn0038393 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001228 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 protein binding ; GO:0005515 | inferred from physical interaction with Bx RNA polymerase II transcription factor binding ; GO:0001085 | inferred from physical interaction with tup transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement RNA polymerase II repressing transcription factor binding ; GO:0001103 | inferred from physical interaction with ush RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 protein binding ; GO:0005515 | inferred from physical interaction with Iswi inferred from physical interaction with Chi inferred from physical interaction with tou transcription factor activity, RNA polymerase II core promoter sequence-specific ; GO:0000983 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ush chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000801139" "dorsal closure ; GO:0007391 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay cardiocyte differentiation ; GO:0035051 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement pericardial nephrocyte differentiation ; GO:0061320 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from genetic interaction with chm chaeta development ; GO:0022416 | inferred from genetic interaction with CtBP chaeta morphogenesis ; GO:0008407 | traceable author statement embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype cardioblast differentiation ; GO:0010002 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement lymph gland development ; GO:0048542 | inferred from mutant phenotype heart contraction ; GO:0060047 | inferred from mutant phenotype cardioblast cell fate determination ; GO:0007510 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | non-traceable author statement cell differentiation ; GO:0030154 | non-traceable author statement transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype pigment metabolic process ; GO:0042440 | inferred from mutant phenotype pattern specification process ; GO:0007389 | non-traceable author statement" nucleus ; GO:0005634 | inferred by curator from GO:0000981 transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 nucleus ; GO:0005634 | inferred from direct assay "pnr, GATA, CG3978, dGATAa, Pnr, prn, GATAa/Pannier, GATAa, dGATAa/pannier, l(3)89B3, CG3978-PA, PNR, GATA4" "IPR013088:Zinc finger, NHR/GATA-type, IPR000679:Zinc finger, GATA-type, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain" CG3978 11-Aug-17 DroID_v2017_08 "Drer\gata3, Drer\trps1, Drer\gata2b, Drer\gata5, Drer\gata2a, Drer\gata4, Drer\gata6, Drer\gata1a, Drer\zglp1, Drer\gata1b" "Scer\GZF3, Scer\GAT2, Scer\GLN3, Scer\SRD1, Scer\GAT4, Scer\GAT3, Scer\GAT1, Scer\ECM23, Scer\DAL80" "Cele\med-2, Cele\elt-4, Cele\end-1, Cele\med-1, Cele\elt-1, Cele\end-3, Cele\nhr-239, Cele\elt-2, Cele\elt-3, Cele\elt-7, Cele\egl-18, Cele\elt-6" "Xtro\gata5, Xtro\gata2, Xtro\gata6, Xtro\gata4, Xtro\gata3, Xtro\trps1, Xtro\gata1" "Mmus\Trps1, Mmus\Zglp1, Mmus\Gata4, Mmus\Gata6, Mmus\Gata2, Mmus\Gata3, Mmus\Gata5, Mmus\Gata1" "Hsap\GATA3, Hsap\ZGLP1, Hsap\GATA2, Hsap\GATA5, Hsap\GATA1, Hsap\GATA6, Hsap\TRPS1, Hsap\GATA4" " embryonic stage | stage 11 , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | stage 6-17 , embryonic stage | 2-12 hr , embryonic stage | stage 8 , embryonic stage | stage 13-15 , embryonic stage | stage 13 , larval stage | third instar stage 2 , larval stage | late third instar larval stage , embryonic stage | stage 6-9 " " dorsal ectoderm

, epidermis | restricted

, organism | 30-60% egg length & dorsal

, organism | 20-60% egg length

, epidermis | dorsal

, proctodeum | anterior to

, posterior spiracle primordium

, cardiogenic mesoderm

, dorsal mesothoracic disc | restricted

, amnioserosa

, eye-antennal disc | restricted

" "visible,somatic clone,cell non-autonomous,recessive,planar polarity defective,short lived,dominant,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,viable,fertile,poor" "embryonic/larval cuticle,cardioblast,embryonic pericardial cell,mesothoracic tergum,medial,somatic clone,adult abdomen,embryonic/larval lymph gland,heart primordium,scutellum,mesothoracic cleft,cardiogenic mesoderm,eye,dorsal,eye disc,photoreceptor cell,ectopic,cell non-autonomous,adult head,antenna,eye equator,embryonic dorsal epidermis,amnioserosa,anterior dorsocentral bristle,posterior dorsocentral bristle,adult heart,dorsocentral bristle,macrochaeta,supernumerary,dorsal medial muscle,scutellar bristle,anterior vertical bristle,postvertical bristle,head,adult thorax,chaeta,epidermis,embryonic garland cell,lymph gland primordium,wing vein,presutural bristle,embryonic epidermis,embryonic/larval pericardial cell,embryo,anterior orbital bristle,wing,scutum,sensory mother cell,embryonic/larval dorsal vessel,embryonic/larval somatic muscle,embryonic/larval visceral muscle,lateral,cell autonomous,microchaeta,postnotum,denticle belt,ventral nerve cord,sternite,tergite,posterior compartment,anterior compartment,embryonic/first instar larval cuticle" FBgn0015239 Hr78 Hormone-receptor-like in 78 http://flybase.org/reports/FBgn0015239 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | traceable author statement" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "DHR78, Dhr78, CG7199, HR78, XR78E/F, NR2D1, Hr78D, Hr78" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type" CG7199 11-Aug-17 DroID_v2017_08 "Drer\ppardb, Drer\nr0b1, Drer\pparg, Drer\nr2e1, Drer\vdrb, Drer\pgr, Drer\rxrab, Drer\rxrga, Drer\vdra, Drer\thrab, Drer\nr1i2, Drer\nr2c2, Drer\ar, Drer\rarab, Drer\nr2c1, Drer\esr2b, Drer\nr2f1b, Drer\pparaa, Drer\raraa, Drer\esrra, Drer\nr2f5, Drer\pparab, Drer\esrrga, Drer\esr2a, Drer\pparda, Drer\rxrba, Drer\nr3c1, Drer\rargb, Drer\nr2e3, Drer\nr2f1a, Drer\esrrd, Drer\nr2f6a, Drer\nr0b2b, Drer\rxrbb, Drer\nr1h4, Drer\nr0b2a, Drer\nr5a1a, Drer\nr6a1b, Drer\esr1, Drer\nr1h5, Drer\nr2f6b, Drer\rxraa, Drer\nr2f2" - "Cele\nhr-41, Cele\nhr-35, Cele\nhr-47" "Xtro\nr6a1, Xtro\rara, Xtro\esr2, Xtro\nr1h2, Xtro\nr2e3, Xtro\pparg, Xtro\ppara, Xtro\esrrb, Xtro\rarg, Xtro\esrra, Xtro\thrb, Xtro\nr1h5, Xtro\rxrg, Xtro\rarb, Xtro\pgr, Xtro\nr2c1, Xtro\nr0b2, Xtro\esrrg, Xtro\rxra, Xtro\nr2f6, Xtro\nr1i2, Xtro\ar, Xtro\nr2c2, Xtro\esrrgr, Xtro\vdr, Xtro\nr2f2, Xtro\nr2f5, Xtro\nr3c2, Xtro\nr3c1, Xtro\ppard, Xtro\esr1, Xtro\nr2f1, Xtro\rxrb, Xtro\nr2e1, Xtro\nr0b1" "Mmus\Nr2c1, Mmus\Nr1h2, Mmus\Ar, Mmus\Ppard, Mmus\Nr2f2, Mmus\Thrb, Mmus\Pparg, Mmus\Nr1h5, Mmus\Ppara, Mmus\Nr1h4, Mmus\Rxra, Mmus\Nr1i3, Mmus\Rarg, Mmus\Thra, Mmus\Nr6a1, Mmus\Nr1h3, Mmus\Nr2f6, Mmus\Rxrb, Mmus\Rarb, Mmus\Nr2e1, Mmus\Nr0b2, Mmus\Esrra, Mmus\Nr1i2, Mmus\Esrrg, Mmus\Rara, Mmus\Nr3c1, Mmus\Pgr, Mmus\Esr2, Mmus\Nr2e3, Mmus\Vdr, Mmus\Rxrg, Mmus\Nr2f1, Mmus\Esr1, Mmus\Nr3c2, Mmus\Nr2c2, Mmus\Esrrb, Mmus\Nr0b1" "Hsap\RXRB, Hsap\THRA, Hsap\NR0B1, Hsap\NR1H3, Hsap\PPARA, Hsap\NR2C2, Hsap\NR3C2, Hsap\RXRA, Hsap\NR1H2, Hsap\NR1I2, Hsap\NR2F2, Hsap\PPARD, Hsap\ESR2, Hsap\AR, Hsap\PPARG, Hsap\NR6A1, Hsap\RARA, Hsap\NR1H4, Hsap\RXRG, Hsap\NR2E1, Hsap\NR2F1, Hsap\PGR, Hsap\THRB, Hsap\RARG, Hsap\ESR1, Hsap\ESRRG, Hsap\RARB, Hsap\ESRRB, Hsap\ESRRA, Hsap\NR0B2, Hsap\NR3C1, Hsap\NR2C1, Hsap\NR1I3, Hsap\NR2F6, Hsap\VDR" " larval stage&&prepupal stage , embryonic stage&&larval stage&&prepupal stage , embryonic stage , larval stage " "

ubiquitous , embryonic/larval salivary gland

" "wild-type,lethal - all die before end of larval stage,recessive,some die during larval stage,female semi-sterile,maternal effect,lethal,neuroanatomy defective,partially lethal - majority die,visible,body color defective,viable" "embryonic/larval tracheal system,embryonic/larval trachea,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0000303 ChAT Choline acetyltransferase http://flybase.org/reports/FBgn0000303 FBgn0064131 protein_coding_gene choline O-acetyltransferase activity ; GO:0004102 | inferred from mutant phenotype choline O-acetyltransferase activity ; GO:0004102 | inferred from direct assay acetylcholine biosynthetic process ; GO:0008292 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype nucleus ; GO:0005634 | non-traceable author statement cytosol ; GO:0005829 | non-traceable author statement "ChAT, cha, ChaT, CG12345, CT23399, dChAT, l(3)91Cc, Cat, Cha, DChAT, ChAt, CLAT_DROME, CHAT, chat" IPR000542:Acyltransferase ChoActase/COT/CPT CG12345 11-Aug-17 DroID_v2017_08 "Drer\cpt1b, Drer\cpt1ab, Drer\cpt1aa, Drer\cpt1cb, Drer\si:ch211-256m1.8, Drer\chata, Drer\chatb, Drer\zgc:154046, Drer\cratb, Drer\LOC101884918, Drer\crata" Scer\CAT2 "Cele\B0395.3, Cele\cha-1" "Xtro\crat.2, Xtro\chat, Xtro\cpt1b, Xtro\LOC100490391, Xtro\crat.1" "Mmus\Chat, Mmus\Cpt1b, Mmus\Cpt1a, Mmus\Cpt1c, Mmus\Crat" "Hsap\CRAT, Hsap\CPT1A, Hsap\CHAT, Hsap\CPT1B, Hsap\CPT1C" adult stage "viable,fertile,phototaxis defective,lethal,recessive,wild-type,locomotor behavior defective,behavior defective,heat sensitive,neuroanatomy defective,somatic clone,neurophysiology defective,paralytic,lethal - all die before end of embryonic stage,some die during embryonic stage" "eye photoreceptor cell & axon & stage 2 third instar larva | somatic clone | conditional ts,eye photoreceptor cell & axon & pupa | somatic clone | conditional ts,lamina anlage,cell non-autonomous,somatic clone,heat sensitive,aCC neuron,RP2 motor neuron,dorsal medial muscle,motor neuron,dendrite" FBgn0263842 CG43703 - http://flybase.org/reports/FBgn0263842 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG43703 IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG43703 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002357 l(3)87Ee lethal (3) 87Ee http://flybase.org/reports/FBgn0002357 - gene - - - "G7, l(3)G7, l(3)87Ee" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,non-enhancer of variegation,non-suppressor of variegation" FBgn0261958 EU119 - http://flybase.org/reports/FBgn0261958 gene - - - EU119 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0034265 Snx16 Sorting nexin 16 http://flybase.org/reports/FBgn0034265 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000543299 phosphatidylinositol binding ; GO:0035091 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with nwk early endosome to late endosome transport ; GO:0045022 | inferred from biological aspect of ancestor with PANTHER:PTN000543299 receptor recycling ; GO:0001881 | inferred from genetic interaction with nwk regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | inferred from biological aspect of ancestor with PANTHER:PTN000543299 protein targeting to lysosome ; GO:0006622 | inferred from biological aspect of ancestor with PANTHER:PTN000543299 regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from genetic interaction with arr inferred from genetic interaction with sgg inferred from genetic interaction with Dad inferred from genetic interaction with wit inferred from genetic interaction with nwk extrinsic component of endosome membrane ; GO:0031313 | inferred from biological aspect of ancestor with PANTHER:PTN000543299 neuromuscular junction ; GO:0031594 | inferred from direct assay multivesicular body ; GO:0005771 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay "CG6410, Snx16, DmSNX16, SNX16" IPR001683:Phox homologous domain CG6410 11-Aug-17 DroID_v2017_08 Drer\snx16 - - Xtro\snx16 Mmus\Snx16 Hsap\SNX16 "neuroanatomy defective,viable,body color defective" "NMJ bouton,supernumerary,multivesicular body,mesothoracic tergum" FBgn0027380 Idefix\pol Idefix element pol http://flybase.org/reports/FBgn0027380 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001969 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001969 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "ORF2, Idefix\pol, pol" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR001969:Aspartic peptidase, active site, IPR012337:Ribonuclease H-like domain" - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037697 GstZ2 Glutathione S transferase Z2 http://flybase.org/reports/FBgn0037697 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay aromatic amino acid family metabolic process ; GO:0009072 | inferred from electronic annotation with InterPro:IPR005955 glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "cg9363, GstZ2, gstz2, CG9363, GSTZ2, gstZ2" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR005955:Glutathione S-transferases, class Zeta, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold, IPR034333:Glutathione S-transferases, class Zeta , N-terminal, IPR034330:Glutathione S-transferases, class Zeta , C-terminal" CG9363 11-Aug-17 DroID_v2017_08 Drer\gstz1 - "Cele\Y53G8B.1, Cele\gst-42, Cele\gst-43" Xtro\gstz1 Mmus\Gstz1 Hsap\GSTZ1 FBgn0039178 CG6356 - http://flybase.org/reports/FBgn0039178 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG6356 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG6356 11-Aug-17 DroID_v2017_08 "Drer\sv2, Drer\slc22a7b.1, Drer\LOC566640, Drer\si:dkey-166k12.1, Drer\oatx, Drer\LOC100334012, Drer\slc22a21, Drer\slc22a2, Drer\slc22a7b.2, Drer\slc22a5, Drer\slc22a13, Drer\slc22a6l, Drer\zgc:153639, Drer\zgc:175176, Drer\slc22a4, Drer\LOC101884074, Drer\slc22a7b.3, Drer\zmp:0000001102" "Scer\PHO84, Scer\YHK8, Scer\DTR1, Scer\QDR2, Scer\GIT1, Scer\TPO2, Scer\HXT5, Scer\TPO1, Scer\QDR1, Scer\AQR1, Scer\HXT2, Scer\TPO3, Scer\HXT9, Scer\FLR1, Scer\QDR3" "Cele\T22F7.1, Cele\F45E10.2, Cele\ZK892.3, Cele\Y51A2D.18, Cele\K09E9.1, Cele\T12B3.2, Cele\F17C11.12, Cele\Y57G11C.23, Cele\Y66D12A.13, Cele\pes-23, Cele\F23F12.3, Cele\T05A1.5, Cele\T08B1.1, Cele\F32H5.4, Cele\Y82E9BR.16, Cele\C44C10.3, Cele\C53B4.1, Cele\F23F12.13" "Xtro\slc22a13, Xtro\slc22a15.2, Xtro\slc22a15.1, Xtro\slc22a6" "Mmus\Slc22a28, Mmus\Slc22a20, Mmus\Slc22a2, Mmus\Slc22a14, Mmus\Svop, Mmus\Slc22a7, Mmus\Slc22a30, Mmus\Sv2c, Mmus\Slc22a29, Mmus\Slc22a15, Mmus\Slc22a26, Mmus\Slc22a19, Mmus\Slc22a8, Mmus\Slc22a13, Mmus\Slc22a3, Mmus\Slc22a4, Mmus\Slc22a22, Mmus\Slc22a6, Mmus\Slc22a16, Mmus\Slc22a27, Mmus\Slc22a1, Mmus\Slc22a23" "Hsap\SLC22A12, Hsap\SLC22A14, Hsap\SLC22A9, Hsap\SLC22A1, Hsap\SLC22A24, Hsap\SLC22A13, Hsap\SVOP, Hsap\SLC22A10, Hsap\SLC22A23, Hsap\SLC22A2, Hsap\SLC22A25, Hsap\SLC22A15, Hsap\SV2C, Hsap\SLC22A6, Hsap\SLC22A11, Hsap\SLC22A3, Hsap\SV2B, Hsap\SLC22A7, Hsap\SLC22A8, Hsap\SLC22A16" viable FBgn0014115 anon-84Bd anon-84Bd http://flybase.org/reports/FBgn0014115 - gene - - - "X, anon-84Bd" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | blastoderm , embryonic stage | stage 6 , embryonic stage | 0-6hr " " organism | 50-70% egg length

, thoracic segment

, cephalic furrow

, cephalic furrow | anterior to

, procephalic segment

, cephalic furrow | posterior to

" FBgn0033869 Cpr50Cb Cuticular protein 50Cb http://flybase.org/reports/FBgn0033869 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr50Cb, CG6305, DmelCpr50Cb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG6305 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0060520 l(3)S102611 lethal (3) S102611 http://flybase.org/reports/FBgn0060520 gene - - - "1026/11, l(3)S102611" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001831 l(1)ts445a lethal (1) ts445a http://flybase.org/reports/FBgn0001831 - gene - - - l(1)ts445a - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0028277 l(1)G0424 lethal (1) G0424 http://flybase.org/reports/FBgn0028277 gene - - - l(1)G0424 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022733 l(2)GPMG-14 lethal (2) GPMG-14 http://flybase.org/reports/FBgn0022733 - gene - - - "GPMG-14, l(2)GPMG-14" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011784 l(3)05050 lethal (3) 05050 http://flybase.org/reports/FBgn0011784 - gene - - - l(3)05050 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267145 CR45585 - http://flybase.org/reports/FBgn0267145 non_protein_coding_gene - - - CR45585 - CR45585 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050435 CG30435 - http://flybase.org/reports/FBgn0050435 protein_coding_gene - - - CG30435 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002052 l(2)37Fe lethal (2) 37Fe http://flybase.org/reports/FBgn0002052 - gene - - - "l(2)E3, l(2)37Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0042630 Sox21b Sox21b http://flybase.org/reports/FBgn0042630 protein_coding_gene - - - "CG6419, CG13483, Sox B2-2, SOXB2.2, SoxB2.2, CG32139, Sox21b" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR009071:High mobility group box domain" CG32139 11-Aug-17 DroID_v2017_08 "Drer\tcf7l1b, Drer\sox7, Drer\sox4a, Drer\sox19a, Drer\sox18, Drer\sox4b, Drer\sox2, Drer\sox1a, Drer\lef1, Drer\sox17, Drer\sox3, Drer\sox21a, Drer\sox14, Drer\sox1b, Drer\LOC103910042, Drer\sox21b, Drer\tcf7l1a, Drer\sox11b, Drer\sox12, Drer\sox19b, Drer\sox8a, Drer\sox11a" "Scer\ROX1, Scer\IXR1" "Cele\sox-3, Cele\sem-2, Cele\sox-4, Cele\sox-2" "Xtro\sox21, Xtro\sox14, Xtro\sox18, Xtro\sox2, Xtro\sox7, Xtro\sox3, Xtro\sox17a, Xtro\sox1, Xtro\sox17b.2, Xtro\sox17b.1" "Mmus\Sox18, Mmus\Sox21, Mmus\Sox8, Mmus\Sox30, Mmus\Sox7, Mmus\Sox14, Mmus\Sox9, Mmus\Sox12, Mmus\Sox4, Mmus\Sox3, Mmus\Sox2, Mmus\Sox17, Mmus\Sox11, Mmus\Sox15, Mmus\Sox1" "Hsap\SOX1, Hsap\SOX14, Hsap\SOX12, Hsap\SOX17, Hsap\SOX30, Hsap\SOX7, Hsap\SOX21, Hsap\SOX18, Hsap\SOX3, Hsap\SOX4, Hsap\SOX2, Hsap\SOX11" "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC23005 K -1.699856266 -1.577460019 FBgn0019936 RpS20 Ribosomal protein S20 http://flybase.org/reports/FBgn0019936 "FBgn0025315, FBgn0025320, FBgn0025322" protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001848, InterPro:IPR005729, InterPro:IPR018268 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR018268 structural constituent of ribosome ; GO:0003735 | non-traceable author statement structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001848, InterPro:IPR005729, InterPro:IPR018268 translation ; GO:0006412 | non-traceable author statement cytoplasmic translation ; GO:0002181 | traceable author statement" small ribosomal subunit ; GO:0015935 | inferred from electronic annotation with InterPro:IPR005729 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement small ribosomal subunit ; GO:0015935 | non-traceable author statement "anon-EST:Posey147, anon-EST:Posey122, anon-EST:Posey111, CG15693, RpS20, Rps20" "IPR018268:Ribosomal protein S10, conserved site, IPR001848:Ribosomal protein S10, IPR005729:Ribosomal protein S10, eukaryotic/archaeal, IPR027486:Ribosomal protein S10 domain" CG15693 11-Aug-17 DroID_v2017_08 Drer\rps20 Scer\RPS20 Cele\rps-20 Xtro\rbm6 Mmus\Rps20 Hsap\RPS20 embryonic stage

ubiquitous lethal DRSC16836 EK 0.282185572 1.008886325 1.67700678 -2.643814823 2.589184646 1.862470273 FBgn0053460 CG33460 - http://flybase.org/reports/FBgn0053460 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SP41, CG8215, CG30086, CR33460, CG33460" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG33460 11-Aug-17 DroID_v2017_08 - - Cele\try-3 - - - FBgn0262789 CR43170 - http://flybase.org/reports/FBgn0262789 pseudogene_attribute - - - "CR43170, chr3LHet_2277384_2278053.0" - CR43170 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263410 CR43456 - http://flybase.org/reports/FBgn0263410 non_protein_coding_gene - - - "CR43456, lincRNA.846" - CR43456 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065238 l(2)SH2161 lethal (2) SH2161 http://flybase.org/reports/FBgn0065238 gene - - - "l(2)SH2161, l(2)SH2 2161" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033529 CG17765 - http://flybase.org/reports/FBgn0033529 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - CG17765 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG17765 11-Aug-17 DroID_v2017_08 "Drer\sri, Drer\pdcd6, Drer\pef1, Drer\zgc:92027, Drer\capns1b, Drer\capns1a" Scer\PEF1 "Cele\cal-5, Cele\M04F3.4" "Xtro\pdcd6, Xtro\gca, Xtro\pef1, Xtro\sri, Xtro\capns2" "Mmus\Pef1, Mmus\Capns1, Mmus\Sri, Mmus\Capns2, Mmus\Pdcd6, Mmus\Capn13, Mmus\Gca" "Hsap\CAPNS2, Hsap\CAPNS1, Hsap\SRI, Hsap\PEF1, Hsap\CAPN13, Hsap\GCA, Hsap\PDCD6" viable FBgn0259596 B1511 - http://flybase.org/reports/FBgn0259596 gene - - - B1511 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "tarsal segment,unguis,arista" FBgn0266417 ringer ringmaker http://flybase.org/reports/FBgn0266417 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype microtubule bundle formation ; GO:0001578 | inferred from direct assay microtubule polymerization ; GO:0046785 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "CG34249, CG4893, HDC10482, CG45027, mdcds_27436, ringer, CG45057" "IPR011992:EF-hand domain pair, IPR008907:P25-alpha" CG45057 11-Aug-17 DroID_v2017_08 "Drer\tppp2, Drer\tppp3, Drer\tppp" - Cele\tppp-1 Xtro\tppp3 "Mmus\Tppp3, Mmus\Tppp2, Mmus\Tppp" "Hsap\TPPP, Hsap\TPPP3, Hsap\TPPP2" FBgn0250907 Cht10 Chitinase 10 http://flybase.org/reports/FBgn0250907 protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR001579 chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitinase activity ; GO:0004568 | non-traceable author statement" "chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 chitin catabolic process ; GO:0006032 | non-traceable author statement" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG18140, CG17682, CG18140-PA3, Cht10, CHT3, DmCHT3, BcDNA:LP04696, Cht1, CHT1, DmCHT1, Cht3, DmCHT10, DmCht1, DmCht3, DmCht10" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR002557:Chitin binding domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG18140 11-Aug-17 DroID_v2017_08 "Drer\chia.4, Drer\chia.2, Drer\si:ch211-226m16.2, Drer\srl, Drer\chia.5, Drer\chia.1, Drer\chia.6, Drer\chia.3, Drer\ovgp1" Scer\CTS2 "Cele\cht-4, Cele\R02F2.4, Cele\cht-2, Cele\cht-1" "Xtro\ctbs, Xtro\chit1, Xtro\chia, Xtro\srl, Xtro\LOC548945" "Mmus\Chil1, Mmus\Chia1, Mmus\Ovgp1, Mmus\Chil6, Mmus\Chit1, Mmus\Chil3, Mmus\Srl, Mmus\Chil4, Mmus\Ctbs, Mmus\Chil5" "Hsap\CTBS, Hsap\CHIT1, Hsap\SRL, Hsap\CHI3L2, Hsap\OVGP1, Hsap\CHI3L1, Hsap\CHIA" FBgn0005526 l(2)52ACc lethal (2) 52ACc http://flybase.org/reports/FBgn0005526 - gene - - - l(2)52ACc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000304 chal chalice http://flybase.org/reports/FBgn0000304 - gene molecular_function ; GO:0003674 | no biological data available ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available chal - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "follicle cell,chorion,dorsal appendage" FBgn0263390 Nha2 Na[+]/H[+] hydrogen antiporter 2 http://flybase.org/reports/FBgn0263390 protein_coding_gene "potassium ion antiporter activity ; GO:0022821 | inferred from genetic interaction with SGD:S000002864,SGD:S000004128 sodium:proton antiporter activity ; GO:0015385 | inferred from direct assay" potassium ion transmembrane transport ; GO:0071805 | inferred from mutant phenotype renal sodium ion transport ; GO:0003096 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006153 brush border ; GO:0005903 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG43442, CG31052, TANGO12, CG4693, CG4682, DmNHA2, Nha2, Tango12, tango12, DMG8-chr3R.34.001, CG43205, nha2" IPR006153:Cation/H+ exchanger CG43442 11-Aug-17 DroID_v2017_08 Drer\si:dkey-162b23.4 - "Cele\F41E7.2, Cele\F41E7.1, Cele\F57G8.5" Xtro\slc9b2 "Mmus\Slc9b1, Mmus\Slc9b2" "Hsap\SLC9B2, Hsap\SLC9B1" FBgn0038498 beat-IIa beaten path IIa http://flybase.org/reports/FBgn0038498 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic integral component of plasma membrane ; GO:0005887 | inferred from sequence model "beat IIa, CT33965, CG14335, CG14334, BcDNA:RE17794, beat-IIa, Beat-IIa" IPR013783:Immunoglobulin-like fold CG14334 11-Aug-17 DroID_v2017_08 Drer\zgc:172106 - - Xtro\f11r - Hsap\CADM2 "viable,fertile" FBgn0005642 wdn wings down http://flybase.org/reports/FBgn0005642 "FBgn0003509, FBgn0004006, FBgn0004365" protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "sry h-l, pqp, sry-h1, sry-c, Sryc, CG1454, wdn" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1454 11-Aug-17 DroID_v2017_08 Drer\si:ch211-241b2.4 - "Cele\fezf-1, Cele\Y55F3AM.14" - Mmus\Zfp626 "Hsap\ZNF780A, Hsap\ZNF582, Hsap\ZNF566" " adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage | early " " oocyte

, nurse cell

" " adult stage && oogenesis stage | stage S1-6 , embryonic stage&&larval stage , adult stage && oogenesis stage | stage S9-10 , adult stage && oogenesis stage | stage >= S7 " " nurse cell

, oocyte

" "viable,fertile,wild-type,visible,recessive,lethal,maternal effect" "wing,maternal effect,anterior crossvein,posterior crossvein,dorsocentral bristle,postalar bristle,scutellar bristle" DRSC17095 E -1.144200891 0.886990845 -1.538075829 0.492230152 1.420399096 1.115790984 FBgn0065334 l(2)SH1866 lethal (2) SH1866 http://flybase.org/reports/FBgn0065334 gene - - - "l(2)SH1866, l(2)SH2 1866" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034517 Cpr57A Cuticular protein 57A http://flybase.org/reports/FBgn0034517 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr57A, CG18066" IPR000618:Insect cuticle protein CG18066 11-Aug-17 DroID_v2017_08 - "Scer\GAL4, Scer\ADA2" Cele\slt-1 - Mmus\Notch1 "Hsap\NOTCH1, Hsap\NOTCH2" viable FBgn0030641 CG6299 - http://flybase.org/reports/FBgn0030641 protein_coding_gene glycolipid transporter activity ; GO:0017089 | inferred from electronic annotation with InterPro:IPR014830 glycolipid binding ; GO:0051861 | inferred from electronic annotation with InterPro:IPR014830 glycolipid transport ; GO:0046836 | inferred from electronic annotation with InterPro:IPR014830 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR014830 CG6299 IPR014830:Glycolipid transfer protein domain CG6299 11-Aug-17 DroID_v2017_08 "Drer\plekha3, Drer\gltpb, Drer\gltpa, Drer\plekha8" - "Cele\Y82E9BR.14, Cele\K08E4.2" "Xtro\gltp, Xtro\plekha3, Xtro\plekha8" "Mmus\Gltp, Mmus\Plekha3, Mmus\Plekha8" "Hsap\PLEKHA8, Hsap\GLTP, Hsap\PLEKHA3" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0036766 CG5506 - http://flybase.org/reports/FBgn0036766 protein_coding_gene - - - "CG5506, BcDNA:LP12049" "IPR006616:DM9 repeat, IPR024518:Domain of unknown function DUF3421" CG5506 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036381 CG8745 - http://flybase.org/reports/FBgn0036381 protein_coding_gene alanine-glyoxylate transaminase activity ; GO:0008453 | inferred from sequence or structural similarity with UniProtKB:Q940M2 pyridoxal phosphate binding ; GO:0030170 | inferred from biological aspect of ancestor with PANTHER:PTN000241033 alanine-glyoxylate transaminase activity ; GO:0008453 | inferred from biological aspect of ancestor with PANTHER:PTN000241036 identical protein binding ; GO:0042802 | inferred from biological aspect of ancestor with PANTHER:PTN000241033 response to nicotine ; GO:0035094 | inferred from expression pattern arginine catabolic process to glutamate ; GO:0019544 | inferred from sequence or structural similarity with UniProtKB:Q940M2 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q940M2 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000241036 CG8745 "IPR005814:Aminotransferase class-III, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG8745 11-Aug-17 DroID_v2017_08 "Drer\phykpl, Drer\etnppl" "Scer\ARG8, Scer\BIO3" Cele\T01B11.2 Xtro\etnppl "Mmus\Etnppl, Mmus\Phykpl" "Hsap\PHYKPL, Hsap\ETNPPL" viable FBgn0033178 CG11127 - http://flybase.org/reports/FBgn0033178 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11127 - CG11127 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002847 msf misformed http://flybase.org/reports/FBgn0002847 - gene - - - msf - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "wing,leg,eye" FBgn0005021 Darkened-eye Darkened eye http://flybase.org/reports/FBgn0005021 - gene - - - "Dke, Darkened-eye" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,dominant,lethal,recessive" "pigment cell,ommatidium" FBgn0262140 CG42866 - http://flybase.org/reports/FBgn0262140 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42866 - CG42866 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065685 l(2)SH0659 lethal (2) SH0659 http://flybase.org/reports/FBgn0065685 gene - - - "l(2)SH0659, l(2)SH2 0659" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0087003 tal tarsal-less http://flybase.org/reports/FBgn0087003 gene_with_polycistronic_transcript - actin filament organization ; GO:0007015 | inferred from mutant phenotype regulation of epidermal cell differentiation ; GO:0045604 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype - "pncr001:3, tal, CR33327, BcDNA:LD11162, MRE29, npcr001:3R, pncr001:3R, l(3)S011041, pri" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,lethal,recessive,visible,somatic clone" "tarsal segment,leg,sex comb,ectopic,tibia,metatarsus,cephalopharyngeal skeleton,embryonic head,joint,somatic clone,ventral thoracic disc,tracheal branch primordium,denticle belt,denticle,posterior spiracle primordium,dorsal hair,embryonic/larval posterior spiracle,taenidial fold,embryonic/larval dorsal branch,embryonic/larval transverse connective,embryonic/larval trachea,external sensory organ,mesothoracic tergum,wing vein L3,wing vein,leg sensillum" FBgn0267828 Fatp Fatty acid (long chain) transport protein http://flybase.org/reports/FBgn0267828 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 long-chain fatty acid transporter activity ; GO:0005324 | inferred from sequence or structural similarity metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "FATP, Fatp, CG46149, fatp, CG7400, dFATP, dFatp, l(2)k10307, anon-WO0121795.74, Dromel_CG7400_FBtr0080133_fatp_mORF, CG45083, Dromel_CG7400_FBtr0080133_fatp_uORF" "IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site" CG46149 11-Aug-17 DroID_v2017_08 "Drer\slc27a6, Drer\slc27a2b, Drer\slc27a4, Drer\zgc:158482, Drer\LOC568883, Drer\slc27a1a, Drer\slc27a2a, Drer\slc27a1b" Scer\FAT1 "Cele\acs-22, Cele\acs-20" "Xtro\slc27a6, Xtro\slc27a3, Xtro\slc27a2" "Mmus\Slc27a3, Mmus\Slc27a4, Mmus\Slc27a6, Mmus\Slc27a5, Mmus\Slc27a2, Mmus\Slc27a1" "Hsap\SLC27A6, Hsap\SLC27A1, Hsap\SLC27A3, Hsap\SLC27A2, Hsap\SLC27A4, Hsap\SLC27A5" "lethal,recessive,neurophysiology defective,cell autonomous,somatic clone,conditional,feeding behavior defective,dominant,long lived,female,heat stress response defective,male limited,cold stress response defective,female limited,oxidative stress response defective,starvation stress response defective,viable,partially lethal - majority die" "eye photoreceptor cell,somatic clone,cell autonomous,conditional,adult heart" FBgn0028902 Tektin-A Tektin A http://flybase.org/reports/FBgn0028902 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 flagellated sperm motility ; GO:0030317 | inferred from biological aspect of ancestor with PANTHER:PTN000462268 cilium movement involved in cell motility ; GO:0060294 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 sperm flagellum ; GO:0036126 | inferred from biological aspect of ancestor with PANTHER:PTN000462268 "CG4767, BG:DS02252.2, anon-WO0140519.235, Tektin-A" IPR000435:Tektin CG4767 11-Aug-17 DroID_v2017_08 "Drer\tekt4, Drer\tekt1, Drer\tekt3, Drer\tekt2" Scer\SPC110 Cele\R02E12.4 "Xtro\tekt1, Xtro\tekt3, Xtro\tekt4, Xtro\tekt2" "Mmus\Tekt3, Mmus\Tekt2, Mmus\Tekt4, Mmus\Tekt5, Mmus\Tekt1" "Hsap\TEKT5, Hsap\TEKT3, Hsap\TEKT1, Hsap\TEKT2, Hsap\TEKT4" viable FBgn0003321 sbr small bristles http://flybase.org/reports/FBgn0003321 "FBgn0030236, FBgn0030238" protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR015245 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VTL1 protein N-terminus binding ; GO:0047485 | inferred from physical interaction with UniProtKB:Q9VSK8 poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from mutant phenotype nuclear export ; GO:0051168 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | traceable author statement mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR015245 nucleoplasm ; GO:0005654 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay "sbr, NXF1, l(1)ts403, dTap, CG1664, PABPr, DmNXF1, nxf1, CT4634, l(1)ts, sbt, l(1)G1, l(1)9Fd, CG17335, NXF1-p15, DNXF-1, Dm nxf1, NFX1, Nxf1" "IPR018222:Nuclear transport factor 2, eukaryote, IPR002075:Nuclear transport factor 2, IPR005637:TAP C-terminal (TAP-C) domain, IPR009060:UBA-like, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR032710:NTF2-like domain, IPR030217:Nuclear RNA export factor, IPR015245:Nuclear RNA export factor Tap, RNA-binding domain, IPR000504:RNA recognition motif domain" CG1664 11-Aug-17 DroID_v2017_08 "Drer\nxf1, Drer\zgc:153681" Scer\MEX67 "Cele\nxf-1, Cele\nxf-2" Xtro\nxf1 "Mmus\Nxf1, Mmus\Nxf2, Mmus\Nxf3, Mmus\Tmem223, Mmus\Nxf7" "Hsap\NXF1, Hsap\NXF2B, Hsap\NXF3, Hsap\NXF5, Hsap\NXF2" "lethal,heat sensitive,visible,viable,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,recessive,male sterile,female sterile,meiotic cell cycle defective,semidominant,partially,sterile,memory defective,germline clone,somatic clone,small body,mitotic cell cycle defective,male,reduced,male fertile,lethal - all die before end of pupal stage,some die during pupal stage" "muscle attachment site,intersegmental nerve,macrochaeta,primary spermatocyte cyst,axoneme,meiosis & nuclear chromosome,scutellar bristle,mesothoracic bristle,metathoracic bristle,head bristle,leg,wing,longitudinal connective,egg chamber,germline clone,somatic clone,embryonic somatic muscle,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4" DRSC20368 IEK 2.191213222 -0.665544386 1.739542964 -0.478426527 0.738271394 1.702083552 FBgn0002284 Prosbeta6 Proteasome beta6 subunit http://flybase.org/reports/FBgn0002284 FBgn0010150 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome core complex ; GO:0005839 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay "pros26, DTS5, l(3)73Ai, Pros26-DTS, beta6_dm, DTS-5, l(3)DTS-5, l(3)DTS5, CG4097, pros26beta6, pros26B, beta6, Pros26, b6, PSMB1, Prosbeta6, PSB1_DROME, Beta-6, beta-6" "IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR023333:Proteasome B-type subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG4097 11-Aug-17 DroID_v2017_08 Drer\psmb1 Scer\PRE7 Cele\pbs-6 Xtro\psmb1 Mmus\Psmb1 Hsap\PSMB1 "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,heat sensitive,dominant,visible,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,hypoactive" "macrochaeta,tormogen cell,ectopic,thecogen cell,eo neuron,trichogen cell,eye,ommatidial precursor cluster,heat sensitive,microchaeta,imaginal disc,adult abdomen,adult head,wing vein,socket,eo sensory structure,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7,abdominal sternite 2,abdominal sternite 3,abdominal sternite 4,abdominal sternite 5,abdominal sternite 6,ommatidium" DRSC11256 IEK -2.262374369 -2.258087669 -0.230988713 -3.380115822 1.641247707 0.286082559 FBgn0039792 CG2267 - http://flybase.org/reports/FBgn0039792 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.167, CG2267" - CG2267 11-Aug-17 DroID_v2017_08 Drer\si:ch73-100l22.3 - - - Mmus\Ccp110 - viable FBgn0051016 CG31016 - http://flybase.org/reports/FBgn0051016 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG9708, CG31016" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG31016 11-Aug-17 DroID_v2017_08 "Drer\p4ha2, Drer\zgc:152670, Drer\p4htm, Drer\p4ha1b, Drer\p4ha3, Drer\p4ha1a, Drer\zgc:158254" - "Cele\dpy-18, Cele\phy-4, Cele\phy-3, Cele\C14E2.4, Cele\phy-2, Cele\Y43F8B.19" "Xtro\p4ha2, Xtro\p4ha3, Xtro\p4ha1" "Mmus\P4ha1, Mmus\P4ha3, Mmus\P4ha2, Mmus\P4htm" "Hsap\P4HTM, Hsap\P4HA1, Hsap\P4HA2, Hsap\P4HA3" viable FBgn0265952 CR44739 - http://flybase.org/reports/FBgn0265952 non_protein_coding_gene - - - "lincRNA.190, CR44739" - CR44739 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038035 lig3 DNA ligase III http://flybase.org/reports/FBgn0038035 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000977, InterPro:IPR012310 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR012308 DNA ligase (ATP) activity ; GO:0003910 | inferred from biological aspect of ancestor with PANTHER:PTN000048695" "DNA biosynthetic process ; GO:0071897 | inferred from electronic annotation with InterPro:IPR000977 DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR000977, InterPro:IPR012308, InterPro:IPR012309, InterPro:IPR012310 DNA ligation involved in DNA repair ; GO:0051103 | inferred from biological aspect of ancestor with PANTHER:PTN000048695" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000048763 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000048763 "lig3, LIG3, CG17227, Lig3, lig 3" "IPR000977:DNA ligase, ATP-dependent, IPR001357:BRCT domain, IPR012309:DNA ligase, ATP-dependent, C-terminal, IPR012310:DNA ligase, ATP-dependent, central, IPR012340:Nucleic acid-binding, OB-fold, IPR016059:DNA ligase, ATP-dependent, conserved site, IPR012308:DNA ligase, ATP-dependent, N-terminal" CG17227 11-Aug-17 DroID_v2017_08 Drer\lig3 Scer\CDC9 Cele\K07C5.3 Xtro\lig3 Mmus\Lig3 Hsap\LIG3 "viable,fertile" FBgn0041622 Or69a Odorant receptor 69a http://flybase.org/reports/FBgn0041622 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "Or69aB, Or69aA, Or69b, 69b, 69a, DOR83, DOR82, 69F.1, CG33264, CG17902, CG32116, Or69a, Or69A, Or69ab, or69a" "IPR004117:Olfactory receptor, insect" CG33264 11-Aug-17 DroID_v2017_08 - - Cele\T11F8.1 - - - viable FBgn0069421 JJF077 JJF077 http://flybase.org/reports/FBgn0069421 gene - - - JJF077 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0053406 5SrRNA:CR33406 5SrRNA:CR33406 http://flybase.org/reports/FBgn0053406 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33406, 5SrRNA:CR33406" - CR33406 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034743 RpS16 Ribosomal protein S16 http://flybase.org/reports/FBgn0034743 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000754, InterPro:IPR020574 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000490829" cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "CG4046, RpS16, bs32d05.y1, S16, Rp S16" "IPR000754:Ribosomal protein S9, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR020574:Ribosomal protein S9, conserved site" CG4046 11-Aug-17 DroID_v2017_08 Drer\rps16 "Scer\RPS16B, Scer\MRPS9, Scer\RPS16A" Cele\rps-16 Xtro\rps16 Mmus\Rps16 Hsap\RPS16 lethal DRSC04442 EK -1.305202557 -1.279659626 -0.366458655 -2.632320288 1.560714645 3.790963013 FBgn0039952 CG17879 - http://flybase.org/reports/FBgn0039952 protein_coding_gene - - - CG17879 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266264 CR44959 - http://flybase.org/reports/FBgn0266264 non_protein_coding_gene - - - CR44959 - CR44959 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067651 sd-4 sd-4 http://flybase.org/reports/FBgn0067651 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,neurophysiology defective,somatic clone,phototaxis defective" FBgn0025335 CG4585 - http://flybase.org/reports/FBgn0025335 - protein_coding_gene - - - "CG4585, CK00282, UD2, anon-60Ab, dCCS4" - CG4585 11-Aug-17 DroID_v2017_08 - - Cele\ddx-35 Xtro\dhx35 - Hsap\DHX35 viable DRSC04475 E 0.14897857 0.367915066 2.440009505 -0.664420502 0.023270135 -0.708386497 FBgn0065424 l(2)SH1516 lethal (2) SH1516 http://flybase.org/reports/FBgn0065424 gene - - - "l(2)SH1516, l(2)SH2 1516" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0066356 l(3)128 lethal (3) 128 http://flybase.org/reports/FBgn0066356 gene - - - l(3)128 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262441 mir-313 mir-313 stem loop http://flybase.org/reports/FBgn0262441 miRNA_gene - head involution ; GO:0008258 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype regulation of synapse structure or activity ; GO:0050803 | inferred from mutant phenotype - "mir-313, Dme-miR-313, CR43003, miR-313, CR33617, dme-mir-313, dme-miR-313" - CR43003 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal,partially lethal - majority die" "wing,wing vein,wing margin,ectopic" FBgn0265844 CR44633 - http://flybase.org/reports/FBgn0265844 non_protein_coding_gene - - - CR44633 - CR44633 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040047 CG17413 - http://flybase.org/reports/FBgn0040047 protein_coding_gene - - - CG17413 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022276 l(2)45Ai lethal (2) 45Ai http://flybase.org/reports/FBgn0022276 - gene - - - "l(2)k00116, l(2)45Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038742 Arc42 Arc42 http://flybase.org/reports/FBgn0038742 protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091, InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity" mediator complex ; GO:0016592 | inferred from sequence or structural similarity "dARC42, CG4703, Arc42" "IPR006089:Acyl-CoA dehydrogenase, conserved site, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal" CG4703 11-Aug-17 DroID_v2017_08 "Drer\acads, Drer\acadm, Drer\zgc:85777, Drer\acad9, Drer\acad8, Drer\acadvl" - "Cele\acdh-4, Cele\acdh-9, Cele\acdh-1, Cele\acdh-7, Cele\acdh-8, Cele\acdh-3" "Xtro\ivd, Xtro\acads, Xtro\acadm, Xtro\MGC147631, Xtro\acad8, Xtro\acad9, Xtro\acadsb" "Mmus\Ivd, Mmus\Acad8, Mmus\Acad9, Mmus\Acads, Mmus\Acadsb, Mmus\Acadvl, Mmus\Acadm" "Hsap\ACADVL, Hsap\ACADM, Hsap\ACADSB, Hsap\ACAD8, Hsap\ACADS, Hsap\IVD, Hsap\ACAD9" "visible,viable,fertile" wing DRSC14340 I 1.823805719 -0.129825336 1.436923689 0.174879457 -0.592074067 -0.423361034 FBgn0038539 Atg8b Autophagy-related 8b http://flybase.org/reports/FBgn0038539 protein_coding_gene protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000000174 macroautophagy ; GO:0016236 | inferred from expression pattern autophagosome ; GO:0005776 | inferred from direct assay "Atg8b, ATG8b, CG12334, atg8b, ATG8, Atg8B, Atg8, atg8B, dAtg8b" "IPR004241:Autophagy protein Atg8 ubiquitin-like, IPR029071:Ubiquitin-related domain" CG12334 11-Aug-17 DroID_v2017_08 "Drer\zgc:92606, Drer\gabarapb, Drer\map1lc3a, Drer\gabarapa, Drer\map1lc3c, Drer\map1lc3b, Drer\map1lc3cl, Drer\gabarapl2" Scer\ATG8 "Cele\lgg-1, Cele\lgg-2" "Xtro\gabarapl1, Xtro\gabarapl2, Xtro\map1lc3c, Xtro\map1lc3b, Xtro\map1lc3a" "Mmus\Map1lc3a, Mmus\Map1lc3b, Mmus\Gabarapl1, Mmus\Gabarapl2, Mmus\Gabarap" "Hsap\MAP1LC3A, Hsap\MAP1LC3B2, Hsap\GABARAPL1, Hsap\MAP1LC3B, Hsap\MAP1LC3C, Hsap\GABARAP, Hsap\GABARAPL2" viable FBgn0004740 l(3)85Dg lethal (3) 85Dg http://flybase.org/reports/FBgn0004740 - gene - - - l(3)85Dg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0062587 Mod(var)1657 Mod(var)1657 http://flybase.org/reports/FBgn0062587 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1657, Mod(var)1657" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0028099 l(3)S073002a lethal (3) S073002a http://flybase.org/reports/FBgn0028099 gene - - - "1382/10, 1323/04, 1152/14, l(3)S073002, l(3)S073002a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000784 fs(1)A1561 female sterile (1) A1561 http://flybase.org/reports/FBgn0000784 - gene - - - "fs(1)1561, fs(1)A1561" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile soma-dependent FBgn0028939 NimC2 Nimrod C2 http://flybase.org/reports/FBgn0028939 protein_coding_gene molecular_function ; GO:0003674 | no biological data available phagocytosis ; GO:0006909 | inferred from sequence or structural similarity with NimC1 integral component of membrane ; GO:0016021 | inferred from sequence model "CG18146, CT40902, BG:DS00180.14, DS00180.14, CG18146-PB, NimC2, nimC2" "IPR000742:EGF-like domain, IPR003341:Cysteine rich repeat, tripleX" CG18146 11-Aug-17 DroID_v2017_08 "Drer\megf10, Drer\si:zfos-2330d3.6, Drer\angptl5, Drer\si:ch1073-110a20.3, Drer\si:ch211-287a12.9, Drer\cuzd1.1, Drer\dkk1a, Drer\LOC100007488, Drer\si:ch1073-110a20.2, Drer\angptl1a, Drer\angpt4, Drer\fgb, Drer\esm1, Drer\si:ch211-157b11.8, Drer\cuzd1.2, Drer\scarf1, Drer\zgc:194887, Drer\megf11, Drer\megf6a, Drer\dkk2, Drer\si:ch1073-110a20.1, Drer\angptl2a, Drer\fga, Drer\si:zfos-2330d3.1, Drer\si:zfos-2330d3.3, Drer\angptl6, Drer\wu:fj11g02, Drer\ltbp3, Drer\tnw, Drer\angptl3, Drer\zgc:158328, Drer\tnxba, Drer\si:zfos-2330d3.8, Drer\megf6b, Drer\tnr, Drer\tnc, Drer\si:ch211-221n20.8, Drer\fibcd1, Drer\tnfaip6, Drer\angptl4, Drer\fgg, Drer\zgc:171687, Drer\angpt2b, Drer\fgl2a, Drer\ccbe1, Drer\angpt1, Drer\zmp:0000000846, Drer\angptl2b, Drer\pear1, Drer\si:ch211-203k16.3, Drer\fgl2b" - "Cele\abu-4, Cele\F35A5.4, Cele\ZC504.1, Cele\Y26D4A.12, Cele\W05B2.2, Cele\Y43C5A.2, Cele\pqn-13, Cele\Y69H2.10, Cele\K10D3.4, Cele\T15B7.1, Cele\Y69H2.3, Cele\M195.2, Cele\M03F4.6, Cele\C08G9.2, Cele\F07H5.8, Cele\ensh-1" "Xtro\tnc, Xtro\LOC100497330, Xtro\fibcd1, Xtro\angptl2, Xtro\mfap4, Xtro\LOC100488177, Xtro\fcn1, Xtro\tnr, Xtro\stab2, Xtro\fgb, Xtro\angpt1, Xtro\angptl4, Xtro\fgl1, Xtro\tnxb, Xtro\angptl3, Xtro\LOC100491105, Xtro\tnn, Xtro\megf11, Xtro\angptl5, Xtro\angpt4, Xtro\tnfaip6, Xtro\fga, Xtro\fcn3, Xtro\fgg, Xtro\fgl2, Xtro\fcn2" "Mmus\Tnfaip6, Mmus\Scarf1, Mmus\Tnc, Mmus\Fga, Mmus\Esm1, Mmus\Clec14a, Mmus\Angptl7, Mmus\Angptl4, Mmus\Fcnb, Mmus\Angpt4, Mmus\Megf10, Mmus\Angpt1, Mmus\Stab1, Mmus\Tnxb, Mmus\Angptl2, Mmus\Tnr, Mmus\Pear1, Mmus\Angptl1, Mmus\Tnn, Mmus\Egfem1, Mmus\Dner, Mmus\Mfap4, Mmus\Fgb, Mmus\Fibcd1, Mmus\Fgl2, Mmus\Angptl6, Mmus\Angpt2, Mmus\Dkk2, Mmus\Megf6, Mmus\Fcna, Mmus\Dkk3, Mmus\Vwde, Mmus\Fgl1, Mmus\Megf11, Mmus\Angptl3, Mmus\Fgg" "Hsap\ANGPT1, Hsap\ANGPTL7, Hsap\ANGPTL5, Hsap\ANGPTL3, Hsap\TNXB, Hsap\ANGPT4, Hsap\FCN3, Hsap\FGG, Hsap\FGA, Hsap\MEGF11, Hsap\TNC, Hsap\FIBCD1, Hsap\MEGF6, Hsap\VWDE, Hsap\PEAR1, Hsap\CLEC14A, Hsap\FGL2, Hsap\TNN, Hsap\ANGPTL1, Hsap\ANGPTL6, Hsap\TNR, Hsap\ANGPTL4, Hsap\FGB, Hsap\SCARF1, Hsap\FCN2, Hsap\MEGF10, Hsap\SCARF2, Hsap\ANGPTL2, Hsap\DKK2, Hsap\FGL1, Hsap\ANGPT2, Hsap\TNFAIP6" viable FBgn0020325 anon-73DFa anon-73DFa http://flybase.org/reports/FBgn0020325 - gene - - - "521, anon-73DFa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0027273 l(1)G0203 lethal (1) G0203 http://flybase.org/reports/FBgn0027273 - gene - - - l(1)G0203 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0263661 CR43652 - http://flybase.org/reports/FBgn0263661 non_protein_coding_gene - - - CR43652 - CR43652 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065438 l(2)SH1468 lethal (2) SH1468 http://flybase.org/reports/FBgn0065438 gene - - - l(2)SH1468 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001656 l(1)ds10 lethal (1) discs small 10 http://flybase.org/reports/FBgn0001656 - gene - - - "l(1)1-74, l(1)ds10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" imaginal disc FBgn0262177 mir-375 mir-375 stem loop http://flybase.org/reports/FBgn0262177 miRNA_gene - - - "miR-375, dme-mir-375, mir-375, MIR-375, CR42884, dme-miR-375, dme-miR-375-3p" - CR42884 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" wing FBgn0032222 CG5037 - http://flybase.org/reports/FBgn0032222 protein_coding_gene protoheme IX farnesyltransferase activity ; GO:0008495 | inferred from electronic annotation with InterPro:IPR006369 cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from sequence or structural similarity with HGNC:2260 farnesyltranstransferase activity ; GO:0004311 | inferred from biological aspect of ancestor with PANTHER:PTN000114243 heme O biosynthetic process ; GO:0048034 | inferred from electronic annotation with InterPro:IPR006369 respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with HGNC:2260 heme biosynthetic process ; GO:0006783 | inferred from sequence or structural similarity with UniProtKB:Q12887 respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with UniProtKB:Q12887 cellular respiration ; GO:0045333 | inferred from biological aspect of ancestor with PANTHER:PTN000114243 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000114243 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000537, InterPro:IPR006369 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000114245 cytochrome complex ; GO:0070069 | inferred from sequence or structural similarity with HGNC:2260" "CG5037, COXX" "IPR000537:UbiA prenyltransferase family, IPR006369:Protohaem IX farnesyltransferase, IPR030470:UbiA prenyltransferase conserved site" CG5037 11-Aug-17 DroID_v2017_08 Drer\cox10 "Scer\COQ2, Scer\COX10" Cele\cox-10 Xtro\cox10 Mmus\Cox10 Hsap\COX10 "viable,fertile,visible" trichogen cell FBgn0010863 l(3)05279 lethal (3) 05279 http://flybase.org/reports/FBgn0010863 - gene - - - l(3)05279 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003603 Su(var)3-12 Suppressor of variegation 3-12 http://flybase.org/reports/FBgn0003603 - gene - - - "Su-var(3)12, Suvar(3)12, Su(var)3-12" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036618 Cpr72Eb Cuticular protein 72Eb http://flybase.org/reports/FBgn0036618 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr72Eb, CG12255" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG12255 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0264948 CR44117 - http://flybase.org/reports/FBgn0264948 non_protein_coding_gene - - - CR44117 - CR44117 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0044026 PK11 Pocket 11 http://flybase.org/reports/FBgn0044026 gene - - - PK11 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266445 CG45075 - http://flybase.org/reports/FBgn0266445 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18783, CG9167, CG45075" - CG45075 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024681 l(1)LefEM20 lethal (1) LefEM20 http://flybase.org/reports/FBgn0024681 - gene - - - "EM20, l(1)LefEM20" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020578 anon-59Cg anon-59Cg http://flybase.org/reports/FBgn0020578 - gene - - - anon-59Cg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016878 l(2)39DEc lethal (2) 39DEc http://flybase.org/reports/FBgn0016878 - gene - - - "D490, l(2)39DEc" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0022968 snRNPD-L snRNPD-L http://flybase.org/reports/FBgn0022968 - gene - - nucleus ; GO:0005634 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from direct assay "D[L], snRNPD-L" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052476 mthl14 methuselah-like 14 http://flybase.org/reports/FBgn0052476 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth response to stress ; GO:0006950 | inferred from electronic annotation with InterPro:IPR010596 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "CG32476, BcDNA:RE31310, mthl14" "IPR023311:Methuselah ectodomain, domain 2, IPR010596:Methuselah, N-terminal domain" CG32476 11-Aug-17 DroID_v2017_08 - - - - Mmus\Adgre1 Hsap\ADGRF4 viable FBgn0010153 l(3)tl lethal (3) tumorous larvae http://flybase.org/reports/FBgn0010153 - gene - - - l(3)tl - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,recessive,lethal - all die before end of larval stage,some die during larval stage" "larval salivary gland & embryo & polytene chromosome,embryonic/larval fat body,embryonic/larval digestive system,melanotic mass,embryonic/larval hemocyte" FBgn0085303 CG34274 - http://flybase.org/reports/FBgn0085303 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34274 "IPR011990:Tetratricopeptide-like helical domain, IPR019734:Tetratricopeptide repeat" CG34274 11-Aug-17 DroID_v2017_08 "Drer\spag1b, Drer\ttc4, Drer\tomm34, Drer\tex11, Drer\dyx1c1, Drer\si:dkey-33c12.4, Drer\zgc:123010, Drer\ttc12, Drer\spag1a" "Scer\TOM71, Scer\SWA2, Scer\SGT2, Scer\TOM70, Scer\CNS1" Cele\C33H5.8 - "Mmus\Tex11, Mmus\Ttc12, Mmus\Spag1, Mmus\Dyx1c1, Mmus\Ttc4, Mmus\Tomm34" "Hsap\TTC4, Hsap\TTC31, Hsap\SPAG1, Hsap\TEX11, Hsap\DYX1C1, Hsap\TTC12, Hsap\TOMM34" FBgn0261607 M(2)28DE Minute (2) 28DE http://flybase.org/reports/FBgn0261607 gene - - - M(2)28DE - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065366 l(2)SH1719 lethal (2) SH1719 http://flybase.org/reports/FBgn0065366 gene - - - l(2)SH1719 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037199 CG11137 - http://flybase.org/reports/FBgn0037199 protein_coding_gene - protein folding in endoplasmic reticulum ; GO:0034975 | inferred from biological aspect of ancestor with PANTHER:PTN000448337 endomembrane system ; GO:0012505 | inferred from direct assay ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN000448337 "CT31141, BcDNA:LD31024, CG11137" "IPR009445:Protein of unknown function DUF1077, TMEM85" CG11137 11-Aug-17 DroID_v2017_08 Drer\emc4 Scer\EMC4 Cele\perm-3 Xtro\emc4 Mmus\Emc4 Hsap\EMC4 viable FBgn0029999 CG1575 - http://flybase.org/reports/FBgn0029999 protein_coding_gene - - Rix1 complex ; GO:0097344 | inferred from biological aspect of ancestor with PANTHER:PTN000411817 MLL1 complex ; GO:0071339 | inferred from biological aspect of ancestor with PANTHER:PTN000411817 CG1575 "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR024679:Pre-rRNA-processing protein IPI1/Testis-expressed sequence 10 protein" CG1575 11-Aug-17 DroID_v2017_08 Drer\tex10 Scer\IPI1 Cele\Y48A6C.4 Xtro\tex10 Mmus\Tex10 Hsap\TEX10 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC18069 K -1.053744179 0.514752277 -0.351634025 0.299704524 -1.513680532 -0.017940009 FBgn0005305 ms(1)202 male sterile (1) 202 http://flybase.org/reports/FBgn0005305 - gene - - - ms(1)202 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,meiotic cell cycle defective" "meiotic cell cycle | male,meiotic cell cycle & nuclear chromosome | male,meiotic cell cycle & spindle | male" FBgn0036760 CG5567 - http://flybase.org/reports/FBgn0036760 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with SGD:S000002395 phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000002395 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002395 dephosphorylation ; GO:0016311 | inferred from biological aspect of ancestor with PANTHER:PTN000445775 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002395 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000445812 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002395 "CG5567, Phos5567, 24666141" "IPR006349:2-phosphoglycolate phosphatase, eukaryotic, IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG5567 11-Aug-17 DroID_v2017_08 "Drer\gbas, Drer\pgp, Drer\nipsnap1, Drer\pdxp" Scer\PHO13 "Cele\F44E7.2, Cele\C45E5.1, Cele\C53A3.2, Cele\K02D10.1, Cele\K09H11.7" "Xtro\pgp, Xtro\nipsnap1" "Mmus\Pdxp, Mmus\Pgp, Mmus\Nipsnap1, Mmus\Gbas" "Hsap\PGP, Hsap\PDXP, Hsap\NIPSNAP1, Hsap\GBAS" viable FBgn0004885 tok tolkin http://flybase.org/reports/FBgn0004885 - protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR015446 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" protein processing ; GO:0016485 | inferred from direct assay negative regulation of gene expression ; GO:0010629 | inferred from direct assay axon guidance ; GO:0007411 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype defasciculation of motor neuron axon ; GO:0007415 | inferred from mutant phenotype - "tlr, tlr-1, Tlr, Tok, CT21251, tldr-1, tldr1, CG6863, tok, tlr1, Tlr-1, TOK" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR000859:CUB domain, IPR001506:Peptidase M12A, IPR001881:EGF-like calcium-binding domain, IPR006026:Peptidase, metallopeptidase, IPR013032:EGF-like, conserved site, IPR015446:Bone morphogenetic protein 1/tolloid-like protein, IPR024079:Metallopeptidase, catalytic domain, IPR034036:Tolloid/BMP1 peptidase domain" CG6863 11-Aug-17 DroID_v2017_08 "Drer\bmp1b, Drer\he2, Drer\bmp1a, Drer\c6ast4, Drer\mep1a.2, Drer\c6ast3, Drer\npsn, Drer\he1b, Drer\LOC797085, Drer\nrp1b, Drer\nrp1a, Drer\cubn, Drer\tll1, Drer\mep1a.1, Drer\he1a, Drer\tnfaip6, Drer\LOC100003133, Drer\pcolce2a, Drer\pcolce2b, Drer\mep1b, Drer\nrp2b, Drer\si:ch73-40a17.3, Drer\c6ast1" - "Cele\nas-33, Cele\nas-37, Cele\ZC116.3, Cele\nas-2, Cele\hch-1, Cele\nas-17, Cele\nas-13, Cele\nas-30, Cele\nas-6, Cele\nas-3, Cele\nas-25, Cele\Y19D10A.6, Cele\nas-19, Cele\nas-39, Cele\nas-27, Cele\nas-32, Cele\nas-29, Cele\nas-31, Cele\nas-8, Cele\nas-1, Cele\nas-28, Cele\nas-24, Cele\nas-14, Cele\nas-4, Cele\nas-15, Cele\toh-1, Cele\nas-36, Cele\nas-12, Cele\nas-7" "Xtro\tll2, Xtro\uvs.2, Xtro\mep1b, Xtro\accs, Xtro\bmp1, Xtro\LOC100489456, Xtro\tnfaip6, Xtro\tll1, Xtro\cubn, Xtro\mep1a, Xtro\LOC100492324" "Mmus\Mep1b, Mmus\Pcolce2, Mmus\C1rl, Mmus\Nrp2, Mmus\Tmprss15, Mmus\Cubn, Mmus\Tnfaip6, Mmus\Adgrg6, Mmus\Pcolce, Mmus\Nrp1, Mmus\Tll1, Mmus\Mep1a, Mmus\Bmp1, Mmus\Astl, Mmus\Tll2" "Hsap\TLL1, Hsap\CUBN, Hsap\C1S, Hsap\ASTL, Hsap\TMPRSS15, Hsap\TMPRSS6, Hsap\BMP1, Hsap\NRP1, Hsap\MEP1A, Hsap\PCOLCE, Hsap\MEP1B, Hsap\TLL2, Hsap\TNFAIP6, Hsap\NRP2, Hsap\ADGRG6, Hsap\PCOLCE2" " larval stage | third instar , embryonic stage , embryonic stage | stage >=12 , embryonic stage | stage 17 , embryonic stage | stage 10 , embryonic stage | blastoderm , embryonic stage | stage >=14 , embryonic stage | cellular blastoderm , embryonic stage | stage 10-11 , embryonic stage -- adult stage , larval stage " " morphogenetic furrow | anterior to

, amnioproctodeal invagination

, visceral mesoderm

, larval brain

, sensillum basiconicum

, embryonic/larval pharynx

, imaginal disc

, peripheral nervous system precursor cluster

, mesectoderm | vicinity of

,

dorsal , peripheral nervous system | restricted

, larval optic lobe

, central nervous system | restricted

, stomodeal invagination

, corpus allatum primordium

, larval outer optic anlage

, somatic mesoderm

, embryonic optic lobe primordium

, eye-antennal disc

, embryonic/larval proventriculus

, larval corpus allatum

" "visible,viable,fertile,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,neuroanatomy defective,developmental rate defective" "wing,embryonic/larval brain,imaginal disc,crossvein,longitudinal connective,intersegmental nerve,A1-7 ventral longitudinal muscle 1,embryonic/larval neuromuscular junction,abdominal segmental nerve,anterior crossvein,posterior crossvein,larval neuromuscular junction & abdominal dorsal acute muscle 1,larval neuromuscular junction & abdominal dorsal oblique muscle 1,larval neuromuscular junction & abdominal dorsal acute muscle 2,larval neuromuscular junction & abdominal dorsal oblique muscle 2,larval neuromuscular junction & abdominal lateral transverse muscle 1,larval neuromuscular junction & abdominal lateral transverse muscle 2,larval neuromuscular junction & abdominal lateral transverse muscle 3,larval neuromuscular junction & abdominal lateral transverse muscle 4,larval neuromuscular junction & abdominal ventral longitudinal muscle 1,larval neuromuscular junction & abdominal ventral longitudinal muscle 2,larval neuromuscular junction & abdominal ventral longitudinal muscle 3,larval neuromuscular junction & abdominal ventral longitudinal muscle 4,larval neuromuscular junction & abdominal ventral acute muscle 1,larval neuromuscular junction & abdominal ventral acute muscle 2,larval neuromuscular junction & abdominal ventral acute muscle 3,larval neuromuscular junction & abdominal ventral oblique muscle 4,larval neuromuscular junction & abdominal ventral oblique muscle 5,larval neuromuscular junction & abdominal ventral oblique muscle 6,segmental nerve,presumptive embryonic/larval central nervous system" FBgn0023489 Pph13 PvuII-PstI homology 13 http://flybase.org/reports/FBgn0023489 FBgn0008638 protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "rhabdomere development ; GO:0042052 | inferred from mutant phenotype ocellus photoreceptor cell development ; GO:0042463 | inferred from genetic interaction with oc compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay regulation of rhodopsin gene expression ; GO:0007468 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Mu, PPH13, CG2819, 60Mun1, Pph13, pph13, hazy" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG2819 11-Aug-17 DroID_v2017_08 "Drer\alx1, Drer\arxa, Drer\mxtx1, Drer\alx3, Drer\phox2bb, Drer\phox2a" - Cele\alr-1 "Xtro\alx1, Xtro\mix1, Xtro\bix1.1, Xtro\mixer" "Mmus\Gm9, Mmus\Arx, Mmus\Esx1, Mmus\Alx3, Mmus\Alx1" "Hsap\ESX1, Hsap\ALX1, Hsap\ALX3, Hsap\ARX" " adult stage , embryonic stage | stage 17 , embryonic stage | stage >=12 " " eye

, photoreceptor cell &&of retina

, medulla

, Bolwig's organ | presumptive

, lamina

, Bolwig's organ | precursor

" "viable,visible,neurophysiology defective,lethal - all die before end of pupal stage,some die during pupal stage" "retina,rhabdomere,subrhabdomeral cisterna,rhabdomere of eye photoreceptor cell" FBgn0035947 Srp68 Signal recognition particle protein 68 http://flybase.org/reports/FBgn0035947 protein_coding_gene 7S RNA binding ; GO:0008312 | inferred from electronic annotation with InterPro:IPR026258 endoplasmic reticulum signal peptide binding ; GO:0030942 | inferred from electronic annotation with InterPro:IPR026258 signal recognition particle binding ; GO:0005047 | inferred from biological aspect of ancestor with PANTHER:PTN000304791 SRP-dependent cotranslational protein targeting to membrane ; GO:0006614 | inferred from electronic annotation with InterPro:IPR026258 protein targeting to ER ; GO:0045047 | inferred from biological aspect of ancestor with PANTHER:PTN000304791 "endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000304791 signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from biological aspect of ancestor with PANTHER:PTN000304791" "CG5064, Srp68" "IPR034652:Signal recognition particle subunit SRP68, RNA-binding domain, IPR026258:Signal recognition particle subunit SRP68" CG5064 11-Aug-17 DroID_v2017_08 Drer\srp68 Scer\SRP68 Cele\srpa-68 Xtro\srp68 Mmus\Srp68 Hsap\SRP68 lethal "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0035600 Cyt-c1 Cytochrome c1 http://flybase.org/reports/FBgn0035600 protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR002326, InterPro:IPR009056 electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity ; GO:0045153 | inferred from sequence or structural similarity with UniProtKB:P08574 electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity ; GO:0045153 | inferred from biological aspect of ancestor with PANTHER:PTN002231577 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity ; GO:0045155 | inferred from biological aspect of ancestor with PANTHER:PTN002231577" "mitochondrial ATP synthesis coupled proton transport ; GO:0042776 | inferred from biological aspect of ancestor with PANTHER:PTN000030137 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:P08574 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000030137" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:P08574 mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN002231577 "anon-EST:Posey141, CG4769, CY1, Cyt-c1" "IPR002326:Cytochrome c1, IPR009056:Cytochrome c-like domain, IPR021157:Cytochrome c1, transmembrane anchor, C-terminal" CG4769 11-Aug-17 DroID_v2017_08 Drer\cyc1 Scer\CYT1 Cele\cyc-1 Xtro\cyc1 Mmus\Cyc1 Hsap\CYC1 "developmental rate defective,RU486 conditional,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,adult heart,RU486 conditional" FBgn0028425 JhI-21 JhI-21 http://flybase.org/reports/FBgn0028425 protein_coding_gene antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 L-amino acid transmembrane transporter activity ; GO:0015179 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 amino acid transmembrane transport ; GO:0003333 | inferred from electronic annotation with InterPro:IPR002293 defense response to fungus ; GO:0050832 | inferred from mutant phenotype leucine import ; GO:0060356 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 "CG12317, JhI-21, Jhl-21, JHI-21" IPR002293:Amino acid/polyamine transporter I CG12317 11-Aug-17 DroID_v2017_08 "Drer\slc7a10a, Drer\slc7a8a, Drer\slc7a8b, Drer\slc7a11, Drer\slc7a9, Drer\slc7a5, Drer\si:ch73-352p4.8, Drer\slc7a14a, Drer\zmp:0000001267, Drer\slc7a6, Drer\slc7a10b, Drer\slc7a7, Drer\si:dkeyp-120h9.1" "Scer\MMP1, Scer\LYP1, Scer\GNP1, Scer\BAP3, Scer\MUP3, Scer\TAT1, Scer\MUP1" "Cele\aat-5, Cele\F23F1.6, Cele\aat-3, Cele\aat-4, Cele\aat-1, Cele\B0454.6, Cele\aat-2" "Xtro\slc7a7, Xtro\LOC100492274, Xtro\slc7a15, Xtro\slc7a5, Xtro\slc7a6, Xtro\slc7a8, Xtro\slc7a10, Xtro\slc7a11, Xtro\slc7a13, Xtro\slc7a9" "Mmus\Slc7a6, Mmus\Slc7a10, Mmus\Slc7a11, Mmus\Slc7a14, Mmus\Slc7a15, Mmus\Slc7a12, Mmus\Slc7a8, Mmus\Slc7a7, Mmus\Slc7a9, Mmus\Slc7a5, Mmus\Slc7a13" "Hsap\SLC7A6, Hsap\SLC7A14, Hsap\SLC7A10, Hsap\SLC7A5, Hsap\SLC7A7, Hsap\SLC7A9, Hsap\SLC7A13, Hsap\SLC7A11, Hsap\SLC7A8" "immune response defective,partially lethal - majority die,some die during pupal stage,viable" "hemocyte,plasmatocyte,crystal cell" FBgn0033450 Lsm11 Lsm11 http://flybase.org/reports/FBgn0033450 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with FLASH protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSU4 U7 snRNA binding ; GO:0071209 | inferred from biological aspect of ancestor with PANTHER:PTN001086338 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype" histone locus body ; GO:0035363 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nuclear body ; GO:0016604 | inferred from direct assay histone pre-mRNA 3'end processing complex ; GO:0071204 | inferred from direct assay U7 snRNP ; GO:0005683 | inferred from biological aspect of ancestor with PANTHER:PTN001086338 cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Lsm11, CG12924, dLsm11, LSM11" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR034109:Sm-like protein Lsm11, middle domain" CG12924 11-Aug-17 DroID_v2017_08 Drer\lsm11 - Cele\C49H3.4 Xtro\lsm11 Mmus\Lsm11 Hsap\LSM11 "fertile,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,recessive" embryonic/larval somatic muscle FBgn0052107 CG32107 - http://flybase.org/reports/FBgn0052107 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32107 "IPR032675:Leucine-rich repeat domain, L domain-like" CG32107 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002022 Catsup Catecholamines up http://flybase.org/reports/FBgn0002022 "FBgn0022172, FBgn0032743" protein_coding_gene enzyme regulator activity ; GO:0030234 | inferred from mutant phenotype zinc ion transmembrane transporter activity ; GO:0005385 | inferred from biological aspect of ancestor with PANTHER:PTN000424313 zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0010312 "zinc II ion transmembrane transport ; GO:0071577 | inferred from biological aspect of ancestor with PANTHER:PTN000424313 detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype cellular zinc ion homeostasis ; GO:0006882 | inferred from biological aspect of ancestor with PANTHER:PTN000424313 regulation of catecholamine metabolic process ; GO:0042069 | inferred from mutant phenotype" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003689 synapse ; GO:0045202 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay perinuclear endoplasmic reticulum ; GO:0097038 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "Catecholamines up, dCATSUP, l(2)k05424, l(2)k05402, l(2)37Bc, Bc, l(2)E13, fs(2)ltoQT50, CG10449, Catsup, catsup, cg10449, dZipCatsup, dZipCATSUP" IPR003689:Zinc/iron permease CG10449 11-Aug-17 DroID_v2017_08 "Drer\slc39a10, Drer\slc39a6, Drer\slc39a8, Drer\slc39a13, Drer\slc39a4, Drer\slc39a7" Scer\YKE4 "Cele\tag-141, Cele\hke-4.1, Cele\C14H10.1, Cele\hke-4.2" "Xtro\slc39a12, Xtro\slc39a6, Xtro\slc39a14, Xtro\slc39a13, Xtro\slc39a8, Xtro\slc39a7, Xtro\slc39a10, Xtro\slc39a4, Xtro\slc39a5" "Mmus\Slc39a7, Mmus\Slc39a14, Mmus\Slc39a5, Mmus\Slc39a12, Mmus\Slc39a13, Mmus\Slc39a4, Mmus\Slc39a10, Mmus\Slc39a6, Mmus\Slc39a8" "Hsap\SLC39A13, Hsap\SLC39A7, Hsap\SLC39A12, Hsap\SLC39A5, Hsap\SLC39A10, Hsap\SLC39A6, Hsap\SLC39A4, Hsap\SLC39A14, Hsap\SLC39A8" "lethal,lethal - all die during first instar larval stage,visible,recessive,somatic clone,wild-type,female sterile,heat sensitive,female fertile,melanotic mass phenotype,dominant,hyperactive,grooming behavior defective,lethal - all die before end of larval stage,some die during larval stage,viable,chemical resistant,cold sensitive,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,body color defective,lethal - all die during larval stage,male,female" "border follicle cell,somatic clone,wing margin,wing blade,crystal cell,melanotic mass,egg,germline clone,dorsal appendage,embryonic/larval dorsal trunk,embryonic/larval tracheal system,adult cuticle,eye,macrochaeta,embryonic/larval salivary gland,pupal cuticle,adult cuticle & adult abdomen,hemolymph,epidermis,adult cuticle & abdomen,macrochaeta & adult abdomen,tergite,adult thorax,wing" FBgn0051165 tRNA:Ser-GCT-2-3 transfer RNA:Serine-GCT 2-3 http://flybase.org/reports/FBgn0051165 tRNA_gene AGC codon-amino acid adaptor activity ; GO:0033446 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033446 cytosol ; GO:0005829 | inferred by curator from GO:0033446 "tRNA[Ser][[2b]], AE002708.trna26-SerGCT, tRNA:S:GCT:AE002708-a, tRNA:ser, tRNA:S, tRNA:ser2b:94A, tRNA:ser2b, tRNA:S2b, tRNA:S2b:94A, CR31165, tRNA[[Ser]], chr3R.trna32-SerGCT, tRNA-Ser-GCT-2-3, tRNA:Ser-GCT-2-3, tRNA:CR31165, AGC" - CR31165 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263248 CG43391 - http://flybase.org/reports/FBgn0263248 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43391 - CG43391 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004749 l(3)89Bb lethal (3) 89Bb http://flybase.org/reports/FBgn0004749 - gene - - - l(3)89Bb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0038749 Xport-A exit protein of rhodopsin and TRP A http://flybase.org/reports/FBgn0038749 protein_coding_gene - "chaperone-mediated protein transport ; GO:0072321 | inferred from direct assay protein localization to rhabdomere ; GO:1990146 | inferred from mutant phenotype retina homeostasis ; GO:0001895 | inferred from mutant phenotype phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype cellular response to light stimulus ; GO:0071482 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype positive regulation of protein targeting to membrane ; GO:0090314 | inferred from mutant phenotype" perinuclear endoplasmic reticulum ; GO:0097038 | inferred from direct assay "CG4468, xport, Xport-A, XPORT-A, xport-A, Xport" - CG4468 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,viable" "rhabdomere of eye photoreceptor cell,conditional,endoplasmic reticulum,Golgi apparatus" FBgn0052193 CG32193 - http://flybase.org/reports/FBgn0052193 protein_coding_gene - - - CG32193 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0000856 fs(1)M49 female sterile (1) M49 http://flybase.org/reports/FBgn0000856 - gene - - - fs(1)M49 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0022961 tardiness tardiness http://flybase.org/reports/FBgn0022961 - gene - - - "t, tardiness" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001074 fs(4)34 female sterile (4) 34 http://flybase.org/reports/FBgn0001074 - gene - - - fs(4)34 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0031908 CG5177 - http://flybase.org/reports/FBgn0031908 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 trehalose-phosphatase activity ; GO:0004805 | NOT inferred from direct assay trehalose biosynthetic process ; GO:0005992 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 trehalose metabolism in response to stress ; GO:0070413 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 extracellular region ; GO:0005576 | inferred from direct assay "CG5177, 28603684, 21430192" "IPR003337:Trehalose-phosphatase, IPR006379:HAD-superfamily hydrolase, subfamily IIB, IPR023214:HAD-like domain" CG5177 11-Aug-17 DroID_v2017_08 - Scer\TPS2 Cele\tps-2 - - - viable FBgn0044468 EP2315 EP2315 http://flybase.org/reports/FBgn0044468 gene - - - EP2315 - - 11-Aug-17 DroID_v2017_08 - - - - - - anterior fascicle & synapse | supernumerary FBgn0085705 CG41579 - http://flybase.org/reports/FBgn0085705 protein_coding_gene - - - CG41579 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036948 CG7298 - http://flybase.org/reports/FBgn0036948 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "anon-EST:ParkEST398, CG7298" IPR002557:Chitin binding domain CG7298 11-Aug-17 DroID_v2017_08 - - "Cele\R02F2.4, Cele\cpg-1, Cele\C39D10.7, Cele\cpg-2" - - - "partially lethal - majority die,some die during pupal stage" FBgn0034729 CG10344 - http://flybase.org/reports/FBgn0034729 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG10344 "IPR001594:Palmitoyltransferase, DHHC domain" CG10344 11-Aug-17 DroID_v2017_08 "Drer\zdhhc21, Drer\zdhhc5a, Drer\zdhhc20a, Drer\zdhhc5b, Drer\zdhhc14, Drer\zdhhc22, Drer\zdhhc9, Drer\zdhhc18a, Drer\zdhhc20b, Drer\zdhhc8b, Drer\zdhhc24, Drer\zgc:77880, Drer\zdhhc23b, Drer\zdhhc3b, Drer\zdhhc1, Drer\zdhhc7, Drer\zdhhc12a, Drer\zdhhc12b, Drer\LOC100334198, Drer\zdhhc3a, Drer\zdhhc23a" "Scer\ERF2, Scer\PFA5" "Cele\dhhc-1, Cele\dhhc-12, Cele\dhhc-9, Cele\dhhc-10" "Xtro\zdhhc24, Xtro\zdhhc3, Xtro\zdhhc1, Xtro\zdhhc12, Xtro\zdhhc14, Xtro\zdhhc21, Xtro\zdhhc7, Xtro\zdhhc8, Xtro\zdhhc9, Xtro\dnz1" "Mmus\Zdhhc12, Mmus\Zdhhc5, Mmus\Zdhhc19, Mmus\Zdhhc24, Mmus\Zdhhc14, Mmus\Zdhhc7, Mmus\Zdhhc20, Mmus\Zdhhc8, Mmus\Zdhhc11, Mmus\Zdhhc9, Mmus\Zdhhc21, Mmus\Zdhhc3, Mmus\Zdhhc18, Mmus\Zdhhc25, Mmus\Zdhhc23, Mmus\Zdhhc22, Mmus\Zdhhc1" "Hsap\ZDHHC14, Hsap\ZDHHC18, Hsap\ZDHHC12, Hsap\ZDHHC20, Hsap\ZDHHC22, Hsap\ZDHHC8, Hsap\ZDHHC1, Hsap\ZDHHC24, Hsap\ZDHHC23, Hsap\ZDHHC9, Hsap\ZDHHC3, Hsap\ZDHHC11, Hsap\ZDHHC5, Hsap\ZDHHC7, Hsap\ZDHHC21, Hsap\ZDHHC19" "viable,visible" mesothoracic tergum FBgn0040164 l(1)G0422 lethal (1) G0422 http://flybase.org/reports/FBgn0040164 gene - - - l(1)G0422 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0058264 CG40264 - http://flybase.org/reports/FBgn0058264 protein_coding_gene - - - CG40264 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034507 CG11192 - http://flybase.org/reports/FBgn0034507 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP82, CG11192" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11192 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.8, Drer\gzmk" - Cele\try-1 Xtro\gzmak "Mmus\Cma2, Mmus\Prss36, Mmus\Prss55, Mmus\Klk14, Mmus\Prss40, Mmus\Tmprss4, Mmus\Prss53" "Hsap\PRSS53, Hsap\PRSS36, Hsap\PRSS38, Hsap\AZU1, Hsap\PRSS27, Hsap\KLK10, Hsap\TPSG1, Hsap\PRSS45, Hsap\PRSS22, Hsap\PRSS33, Hsap\PRSS8, Hsap\PRSS57" viable FBgn0265467 CR44360 - http://flybase.org/reports/FBgn0265467 non_protein_coding_gene - - - CR44360 - CR44360 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010438 mtSSB mitochondrial single stranded DNA-binding protein http://flybase.org/reports/FBgn0010438 - protein_coding_gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay single-stranded DNA binding ; GO:0003697 | inferred from sequence or structural similarity with UniProtKB:Q04837 mitochondrial genome maintenance ; GO:0000002 | inferred from direct assay inferred from mutant phenotype mitochondrial DNA replication ; GO:0006264 | inferred from direct assay mitochondrial chromosome ; GO:0000262 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q04837 mitochondrion ; GO:0005739 | inferred from direct assay "lopo, 0046/13, DmmtSSB, SSB, c3a, CG4337, mtSSB, SSB_DROME" "IPR000424:Primosome PriB/single-strand DNA-binding, IPR011344:Single-stranded DNA-binding protein, IPR012340:Nucleic acid-binding, OB-fold" CG4337 11-Aug-17 DroID_v2017_08 Drer\ssbp1 Scer\RIM1 Cele\mtss-1 Xtro\ssbp1 Mmus\Ssbp1 Hsap\SSBP1 " embryonic stage -- adult stage , embryonic stage , embryonic stage | early , oogenesis stage && adult stage | female " " posterior midgut proper primordium

,

ubiquitous , ovary

, anterior embryonic/larval midgut

, posterior embryonic/larval midgut

, anterior midgut proper primordium

" "viable,fertile,lethal,recessive,cell growth defective,wild-type,visible" "larval midgut & mitochondrion,trichogen cell" DRSC17005 EK 0.896460492 0.067973094 2.029190659 0.144965595 1.784392763 -0.427941742 FBgn0034853 Ice1 Interacts with the C terminus of ELL 1 http://flybase.org/reports/FBgn0034853 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay snRNA transcription from RNA polymerase II promoter ; GO:0042795 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype transcriptionally active chromatin ; GO:0035327 | inferred from mutant phenotype ELL-EAF complex ; GO:0032783 | inferred from physical interaction with Su(Tpl) transcription elongation factor complex ; GO:0008023 | inferred from direct assay "CG13550, Ice1, dICE1, ICE1" - CG13550 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0051465 CG31465 - http://flybase.org/reports/FBgn0051465 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6670, CG31465" IPR005468:Avidin/streptavidin CG31465 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0004799 fs(2)ltoHE41 female sterile (2) ltoHE41 http://flybase.org/reports/FBgn0004799 - gene molecular_function ; GO:0003674 | no biological data available ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoHE41 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0029666 CG10803 - http://flybase.org/reports/FBgn0029666 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR008858 - - "CG10803, rop-1" IPR008858:TROVE domain CG10803 11-Aug-17 DroID_v2017_08 Drer\trove2 - Cele\rop-1 Xtro\trove2 Mmus\Trove2 Hsap\TROVE2 viable FBgn0001746 l(1)HM18 lethal (1) HM18 http://flybase.org/reports/FBgn0001746 - gene - - - l(1)HM18 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0053333 CG33333 - http://flybase.org/reports/FBgn0053333 protein_coding_gene - - - CG33333 - CG33333 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266702 CR45192 - http://flybase.org/reports/FBgn0266702 non_protein_coding_gene - - - CR45192 - CR45192 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000705 fltK flight defective K http://flybase.org/reports/FBgn0000705 - gene - - - fltK - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,jumping defective,partially" FBgn0264478 CG43886 - http://flybase.org/reports/FBgn0264478 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43886, lincRNA.469" - CG43886 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260621 2L2798 - http://flybase.org/reports/FBgn0260621 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2798 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0041172 ade4 ade4 http://flybase.org/reports/FBgn0041172 gene - - - ade4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye color defective,recessive,auxotroph" pigment cell FBgn0264350 CR43806 - http://flybase.org/reports/FBgn0264350 non_protein_coding_gene - - - CR43806 - CR43806 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065357 l(2)SH1756 lethal (2) SH1756 http://flybase.org/reports/FBgn0065357 gene - - - "l(2)SH1756, l(2)SH2 1756" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065328 l(2)SH1894 lethal (2) SH1894 http://flybase.org/reports/FBgn0065328 gene - - - "l(2)SH1894, l(2)SH2 1894" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0063386 snoRNA:Me18S-A28a - http://flybase.org/reports/FBgn0063386 snoRNA_gene - - - "U27snoRNA, CR32902, snoRNA:Me18S-A28a, Me18S-A28a(U27), snoRNA:U27:54Ec" - CR32902 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262075 JC13 - http://flybase.org/reports/FBgn0262075 gene - response to anesthetic ; GO:0072347 | inferred from mutant phenotype - JC13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical sensitive,recessive" FBgn0036708 CG13725 - http://flybase.org/reports/FBgn0036708 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13725 IPR031754:Protein of unknown function DUF4736 CG13725 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0002909 mus312 mutagen-sensitive 312 http://flybase.org/reports/FBgn0002909 FBgn0035764 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with slx1 protein binding ; GO:0005515 | inferred from physical interaction with mei-9 3'-flap endonuclease activity ; GO:0048257 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001853063 crossover junction endodeoxyribonuclease activity ; GO:0008821 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001853063 5'-flap endonuclease activity ; GO:0017108 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001853063 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VN41 "DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR018574 meiotic chromosome segregation ; GO:0045132 | inferred from mutant phenotype oocyte fate determination ; GO:0030716 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from genetic interaction with Blm mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype inferred from genetic interaction with nbs nucleotide-excision repair, DNA damage recognition ; GO:0000715 | NOT inferred from mutant phenotype reciprocal DNA recombination ; GO:0035825 | inferred from genetic interaction with Fancm interstrand cross-link repair ; GO:0036297 | inferred from biological aspect of ancestor with PANTHER:PTN001853063 resolution of meiotic recombination intermediates ; GO:0000712 | inferred from mutant phenotype meiotic DNA double-strand break processing ; GO:0000706 | inferred from biological aspect of ancestor with PANTHER:PTN001853063 cell proliferation ; GO:0008283 | inferred from genetic interaction with Blm" protein complex ; GO:0043234 | inferred from direct assay Slx1-Slx4 complex ; GO:0033557 | inferred from direct assay "CG8601, mus(3)312, mus312, MUS312" IPR018574:Structure-specific endonuclease subunit Slx4 CG8601 11-Aug-17 DroID_v2017_08 Drer\slx4 - Cele\him-18 - Mmus\Slx4 Hsap\SLX4 "radiation sensitive,chemical sensitive,recessive,meiotic cell cycle defective,viable" presumptive oocyte DRSC11008 K 0.007082853 0.322142703 0.156995852 -0.08572813 2.086020639 0.284607949 FBgn0004785 anon-g anon guanine-rich sequence http://flybase.org/reports/FBgn0004785 - repeat_region - - - anon-g - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061151 l(2)K152 lethal (2) K152 http://flybase.org/reports/FBgn0061151 gene - - - "K152, l(2)K152" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028899 CG31817 - http://flybase.org/reports/FBgn0028899 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "DS02740.18, BG:DS02740.18, anon-WO03042407.99, anon-WO03042407.98, CG31817" - CG31817 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC01537 IEK -1.706612885 0.726853781 -1.925911061 0.065487358 2.558978342 0.492616223 FBgn0025502 l(3)73Al lethal (3) 73Al http://flybase.org/reports/FBgn0025502 - gene - - - l(3)73Al - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011020 Sas-4 Spindle assembly abnormal 4 http://flybase.org/reports/FBgn0011020 FBgn0037480 protein_coding_gene "protein complex scaffold ; GO:0032947 | inferred from physical interaction with Cp190, cnn, Plp, asl" centrosome duplication ; GO:0051298 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype centrosome separation ; GO:0051299 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype microtubule polymerization ; GO:0046785 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from direct assay male meiosis ; GO:0007140 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay pericentriolar material ; GO:0000242 | inferred from direct assay tubulin complex ; GO:0045298 | colocalizes_with inferred from direct assay centriole ; GO:0005814 | colocalizes_with inferred from direct assay "DSas-4, CG10061, l(3)S2214, Sas-4, l(3)s2214, DSAS-4, D-Sas4, dsas-4, SAS4, DSas4, Sas4, SAS-4, sas-4, Dsas-4, sas4, d-SAS-4, Dsas4, D-sas4, CPAP" "IPR009852:T-complex protein 10, C-terminal domain, IPR026581:T-complex protein 10 family" CG10061 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-140l13.3, Drer\cenpj" - Cele\pqe-1 Xtro\cenpj "Mmus\Cenpj, Mmus\Tcp10b, Mmus\Tcp10c, Mmus\Tcp10a" "Hsap\CENPJ, Hsap\TCP10L2, Hsap\TCP10, Hsap\TCP10L" "mitotic cell cycle defective,cytokinesis defective,uncoordinated,mating defective,male sterile,lethal,recessive,cell polarity defective,somatic clone,cell cycle defective,meiotic cell cycle defective,developmental rate defective,some die during immature adult stage,viable,visible" "male germline stem cell,spermatid axoneme,aster, with Sas-4s2214,embryonic/larval brain,spindle,neuroblast,centriole,centrosome,cilium,flagellum (obsolete ),spermatid,sensory neuron,primary spermatocyte,aster, with Sas-4‘îT.TAvicGFP,centriole | ectopicmat.‘±Tub67C.THsimVP16,trichogen cell,supernumerary" FBgn0034451 TBCB tubulin-binding cofactor B http://flybase.org/reports/FBgn0034451 protein_coding_gene - establishment of apical/basal cell polarity ; GO:0035089 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype oocyte axis specification ; GO:0007309 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG11242, TBCB, dTBCB, tbcb" "IPR000938:CAP Gly-rich domain, IPR029071:Ubiquitin-related domain, IPR000626:Ubiquitin domain" CG11242 11-Aug-17 DroID_v2017_08 Drer\tbcb "Scer\BIK1, Scer\ALF1, Scer\NIP100" Cele\tbcb-1 Xtro\tbcb Mmus\Tbcb Hsap\TBCB "cell cycle defective,recessive,cell polarity defective,germline clone,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile,partially lethal - majority live,visible" "oocyte,germline clone,nurse cell,somatic clone,follicle cell,neuroblast,wing" FBgn0031097 obst-A obstructor-A http://flybase.org/reports/FBgn0031097 protein_coding_gene chitin binding ; GO:0008061 | inferred from direct assay chitin binding ; GO:0008061 | inferred from reviewed computational analysis "chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype negative regulation of extracellular matrix disassembly ; GO:0010716 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay "obst-A, CG17052, obst, Obst-A" IPR002557:Chitin binding domain CG17052 11-Aug-17 DroID_v2017_08 - - "Cele\cpg-2, Cele\dct-9, Cele\R02F2.4, Cele\cbd-1" - - - "lethal,small body,lethal - all die before end of larval stage,recessive,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval tracheal system,embryonic/first instar larval cuticle,cuticle,taenidial fold,trichogen cell" FBgn0031016 kek5 kekkon5 http://flybase.org/reports/FBgn0031016 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 axonogenesis ; GO:0007409 | inferred from biological aspect of ancestor with PANTHER:PTN000689992 regulation of BMP signaling pathway ; GO:0030510 | inferred from direct assay negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | NOT inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay "CG12199, CT10486, Kek5, kek5" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR003591:Leucine-rich repeat, typical subtype, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR011989:Armadillo-like helical, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR001611:Leucine-rich repeat, IPR013098:Immunoglobulin I-set, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype" CG12199 11-Aug-17 DroID_v2017_08 "Drer\lrrc38a, Drer\slitrk1, Drer\lrit3a, Drer\si:dkey-52j6.3, Drer\si:dkey-1j5.4, Drer\islr2, Drer\slitrk4, Drer\LOC101882074, Drer\lrrc24, Drer\lrit1a, Drer\slitrk6, Drer\lrit1b, Drer\lrrc38b, Drer\lrtm2a, Drer\lrtm2b, Drer\slitrk2, Drer\slitrk5b, Drer\lrit2, Drer\slitrk3b, Drer\lrit3b, Drer\lrtm1" - "Cele\dma-1, Cele\pxn-1, Cele\iglr-3" "Xtro\lrrc15, Xtro\slitrk6, Xtro\islr2, Xtro\lrrc52, Xtro\lrit2, Xtro\slitrk1, Xtro\lrtm2, Xtro\lrit3, Xtro\lrrc24" "Mmus\Lrrc24, Mmus\Lrrc26, Mmus\Lrit1, Mmus\Lgr6, Mmus\Islr, Mmus\Islr2, Mmus\Lrtm2, Mmus\Lrtm1, Mmus\Lrit3, Mmus\Lrit2, Mmus\Slitrk3, Mmus\Slitrk2, Mmus\Lrrc52, Mmus\Flrt1, Mmus\Slitrk6, Mmus\Slitrk1, Mmus\Slitrk5, Mmus\Amigo3, Mmus\Lrrc55, Mmus\Flrt2, Mmus\Lrrc38, Mmus\Slitrk4" "Hsap\LRRC38, Hsap\LRIT2, Hsap\SLITRK4, Hsap\LRRC19, Hsap\LRRC52, Hsap\LRRC26, Hsap\LRTM2, Hsap\LRRC24, Hsap\SLITRK2, Hsap\LRTM1, Hsap\SLITRK5, Hsap\SLITRK6, Hsap\ISLR2, Hsap\SLITRK3, Hsap\ISLR, Hsap\LRIT1, Hsap\FLRT2, Hsap\LRIT3, Hsap\LRRC55, Hsap\SLITRK1" "viable,fertile,visible,recessive,short lived,size defective" "crossvein,wing blade,anterior crossvein,wing,posterior crossvein,scutellar bristle,supernumerary,mesothoracic tergum" FBgn0031467 Cpr23B Cuticular protein 23B http://flybase.org/reports/FBgn0031467 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr23B, CG2973, DmelCpr23B" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2973 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable DRSC00555 E -0.803928344 1.448963303 3.57083133 -0.411181556 0.487095223 0.551315949 FBgn0027108 Inx2 Innexin 2 http://flybase.org/reports/FBgn0027108 "FBgn0026672, FBgn0026693, FBgn0026703, FBgn0026707, FBgn0027220, FBgn0027325, FBgn0028356, FBgn0029062" protein_coding_gene gap junction channel activity ; GO:0005243 | inferred by curator from GO:0005921 gap junction channel activity ; GO:0005243 | inferred from direct assay germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype intercellular transport ; GO:0010496 | inferred from direct assay foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype cell communication ; GO:0007154 | inferred from direct assay gap junction ; GO:0005921 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement "inx-2, D-inx-2, kropf, Inx2, CG4590, Dm-inx2, Dm-inx, prp33, Ix2, l(1)G0036, l(1)G0035, l(1)G0043, l(1)G0317, l(1)G0118, l(1)G0059, l(1)G0157, l(1)G0364, INX-2, inx2, FBpp0291074" IPR000990:Innexin CG4590 11-Aug-17 DroID_v2017_08 "Drer\panx1b, Drer\panx3" - "Cele\inx-11, Cele\inx-3, Cele\unc-7, Cele\inx-7, Cele\inx-16, Cele\inx-2, Cele\inx-17, Cele\inx-9, Cele\inx-22, Cele\inx-18, Cele\inx-8, Cele\inx-19, Cele\inx-13, Cele\inx-1, Cele\inx-20, Cele\inx-10, Cele\inx-15, Cele\eat-5, Cele\inx-5, Cele\inx-6, Cele\che-7, Cele\inx-12, Cele\unc-9, Cele\inx-21, Cele\inx-14" - - - "lethal,recessive,female,lethal - all die during embryonic stage,viable,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,neurophysiology defective,visual behavior defective,female sterile,feeding behavior defective,small body,increased cell death,rescuable maternal effect,cell shape defective,partially lethal - majority die,smell perception defective,partially,lethal - all die before end of pupal stage,some die during pupal stage,visible,lethal - all die during first instar larval stage" "ovary,germarium,female germline cell,synaptic vesicleMz709,photoreceptor cell,embryonic hindgut,embryonic Malpighian tubule,presumptive embryonic salivary gland,presumptive embryonic/larval tracheal system,embryonic foregut,embryonic/first instar larval cuticle,rescuable maternal effect,embryonic head,embryonic segment,embryonic epidermis,embryonic/larval proventriculus,proventriculus primordium,trichogen cell,egg chamber" FBgn0262739 AGO1 Argonaute-1 http://flybase.org/reports/FBgn0262739 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with AGO2 enzyme binding ; GO:0019899 | inferred from physical interaction with Dcr-1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 miRNA binding ; GO:0035198 | inferred from direct assay chromatin silencing ; GO:0006342 | inferred from mutant phenotype synapse assembly ; GO:0007416 | traceable author statement mRNA cleavage involved in gene silencing by miRNA ; GO:0035279 | inferred from mutant phenotype RNA interference ; GO:0016246 | traceable author statement germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype targeting of mRNA for destruction involved in RNA interference ; GO:0030423 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from genetic interaction with Dcr-1 inferred from genetic interaction with AGO2 habituation ; GO:0046959 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from mutant phenotype inferred from genetic interaction with gw regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype production of miRNAs involved in gene silencing by miRNA ; GO:0035196 | inferred from mutant phenotype mRNA cleavage involved in gene silencing by miRNA ; GO:0035279 | inferred from direct assay germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Ago1, ago1, Ago-1, AGO1, dAGO1, CG6671, Ago, dAgo1, Dm Ago1, ago1-1, l(2)k08121, l(2)k00208, l(2)04845, l(2)4845, anon-WO0257455.29, MRE20, DmAgo1, Agp1, AGO-1, argonaute1" "IPR003100:PAZ domain, IPR003165:Piwi domain, IPR012337:Ribonuclease H-like domain, IPR014811:Argonaute, linker 1 domain, IPR032473:Protein argonaute, Mid domain, IPR032474:Protein argonaute, N-terminal, IPR032472:Argonaute linker 2 domain" CG6671 11-Aug-17 DroID_v2017_08 "Drer\ago2, Drer\LOC567622, Drer\piwil1, Drer\ago1, Drer\piwil2, Drer\ago4, Drer\ago3b" - "Cele\alg-3, Cele\ppw-2, Cele\rde-1, Cele\ZK218.8, Cele\wago-4, Cele\wago-10, Cele\ergo-1, Cele\C04F12.1, Cele\nrde-3, Cele\wago-5, Cele\prg-2, Cele\sago-2, Cele\wago-1, Cele\wago-11, Cele\alg-2, Cele\alg-4, Cele\sago-1, Cele\hrde-1, Cele\alg-1, Cele\ppw-1, Cele\hpo-24, Cele\prg-1, Cele\C03D6.1" "Xtro\ago4, Xtro\piwil3, Xtro\ago2, Xtro\piwil4, Xtro\ago3, Xtro\piwil2" "Mmus\Piwil1, Mmus\Ago3, Mmus\Ago1, Mmus\Piwil4, Mmus\Ago4, Mmus\Piwil2, Mmus\Ago2" "Hsap\AGO3, Hsap\AGO4, Hsap\PIWIL2, Hsap\PIWIL4, Hsap\AGO1, Hsap\PIWIL1, Hsap\AGO2" DRSC05912 I -2.003046054 2.415274581 1.091121184 0.605080755 1.17027256 1.378684056 FBgn0039449 CG6425 - http://flybase.org/reports/FBgn0039449 protein_coding_gene - - - CG6425 - CG6425 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0025736 puri puri http://flybase.org/reports/FBgn0025736 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available puri - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "wing,somatic clone" FBgn0036398 upSET upSET http://flybase.org/reports/FBgn0036398 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 core promoter binding ; GO:0001047 | inferred from direct assay histone methyltransferase activity ; GO:0042054 | NOT inferred from direct assay establishment of chromatin silencing ; GO:0006343 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from mutant phenotype transcriptionally active chromatin ; GO:0035327 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "upSET, CG9007" "IPR001214:SET domain, IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9007 11-Aug-17 DroID_v2017_08 "Drer\whsc1l1, Drer\kmt2d, Drer\setd5, Drer\whsc1, Drer\phf20b, Drer\phf3, Drer\phf20l1, Drer\setd1ba, Drer\nsd1b, Drer\kmt2e, Drer\phf20a, Drer\ash1l" "Scer\SET1, Scer\BYE1, Scer\SET4, Scer\SET3, Scer\CTI6, Scer\SET2" "Cele\lin-59, Cele\set-26, Cele\set-16, Cele\Y73B3A.1, Cele\set-24, Cele\C16A11.4, Cele\set-5, Cele\set-9, Cele\set-12, Cele\met-1, Cele\mes-4, Cele\C16A11.3" "Xtro\setd1b, Xtro\phf20l1, Xtro\kmt2e, Xtro\setd5" "Mmus\Nsd1, Mmus\Whsc1l1, Mmus\Whsc1, Mmus\Setd5, Mmus\Phf13, Mmus\Ash1l, Mmus\Kmt2e, Mmus\Kmt2c, Mmus\Kmt2d, Mmus\Setd1b, Mmus\Phf3, Mmus\Setd1a, Mmus\Phf20l1, Mmus\Dido1, Mmus\Spocd1, Mmus\Setd2" "Hsap\WHSC1L1, Hsap\ASH1L, Hsap\SETD1A, Hsap\PHF20L1, Hsap\KMT2E, Hsap\KMT2C, Hsap\NSD1, Hsap\KMT2D, Hsap\SETD1B, Hsap\DIDO1, Hsap\SETD5, Hsap\WHSC1, Hsap\SETD2, Hsap\PHF20" "viable,female sterile,recessive" "egg chamber,nurse cell,heart primordium" FBgn0264642 denuded denuded http://flybase.org/reports/FBgn0264642 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - denuded - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0019675 mor(1)4 mortality gene (1)4 http://flybase.org/reports/FBgn0019675 - gene - - - mor(1)4 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0004506 fs(1)K4 female sterile (1) K4 http://flybase.org/reports/FBgn0004506 - gene - - - fs(1)K4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,recessive" egg FBgn0266633 CR45140 - http://flybase.org/reports/FBgn0266633 non_protein_coding_gene - - - CR45140 - CR45140 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050234 tRNA:Leu-AAG-1-2 transfer RNA:Leucine-AAG 1-2 http://flybase.org/reports/FBgn0050234 tRNA_gene CUU codon-amino acid adaptor activity ; GO:0033417 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033417 cytosol ; GO:0005829 | inferred by curator from GO:0033417 "CR30234, AE002787.trna13-LeuAAG, tRNA:L:AAG:AE002787-a, chr2R.trna71-LeuAAG, tRNA-Leu-AAG-1-2, tRNA:Leu-AAG-1-2, tRNA:CR30234, CUU" - CR30234 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0067061 P270 P270 http://flybase.org/reports/FBgn0067061 gene - - - P270 - - 11-Aug-17 DroID_v2017_08 - - - - - - neurophysiology defective FBgn0033191 CG1598 - http://flybase.org/reports/FBgn0033191 protein_coding_gene "ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR016300, InterPro:IPR027542 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR016300, InterPro:IPR027542" - - "gh10483, BEST:GH10483, BcDNA:GM18141, CG1598" "IPR025723:Anion-transporting ATPase-like domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027542:Arsenical pump ATPase, ArsA/GET3, eukaryotic, IPR016300:Arsenical pump ATPase, ArsA/GET3" CG1598 11-Aug-17 DroID_v2017_08 Drer\asna1 Scer\GET3 Cele\asna-1 Xtro\asna1 Mmus\Asna1 Hsap\ASNA1 viable DRSC06598 K -0.435135758 -0.093731261 -0.713471094 0.138290512 -1.530166423 -0.33084254 FBgn0035245 GC gamma-glutamyl carboxylase http://flybase.org/reports/FBgn0035245 protein_coding_gene gamma-glutamyl carboxylase activity ; GO:0008488 | inferred from direct assay protein carboxylation ; GO:0018214 | inferred from direct assay peptidyl-glutamic acid carboxylation ; GO:0017187 | inferred from direct assay - "CG13927, dGC, GC, DgammaC, gammaC, dgammaC" "IPR007782:Vitamin K-dependent gamma-carboxylase, IPR011020:HTTM" CG13927 11-Aug-17 DroID_v2017_08 Drer\ggcx - - Xtro\ggcx Mmus\Ggcx Hsap\GGCX "viable,fertile" FBgn0051704 CG31704 - http://flybase.org/reports/FBgn0051704 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG31704 IPR002350:Kazal domain CG31704 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-77g12.1, Drer\zgc:158852, Drer\spink4, Drer\si:dkey-203a12.8, Drer\tmeff1b, Drer\tmeff2a, Drer\si:dkey-203a12.2, Drer\tmeff2b, Drer\si:dkey-203a12.7" - Cele\ZK813.6 Xtro\tmeff1 "Mmus\Spink4, Mmus\Tmeff2, Mmus\Spink10, Mmus\Gm10267, Mmus\Spink2, Mmus\Spink14, Mmus\Tmeff1, Mmus\Spink13, Mmus\Spink1, Mmus\Spink6" "Hsap\SPINK13, Hsap\TMEFF2, Hsap\SPINK14, Hsap\SPINK2, Hsap\SPINK7, Hsap\TMEFF1, Hsap\SPINK6, Hsap\SPINK9, Hsap\SPINK1, Hsap\SPINK4" "viable,lethal - all die before end of pupal stage,some die during pupal stage" DRSC22118 I -0.083424612 -2.815756413 1.002525336 0.0670848 -0.51600523 -0.140750912 FBgn0005178 l(2)S1 lethal of Seto http://flybase.org/reports/FBgn0005178 - gene - - - l(2)S1 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal puparium FBgn0086203 S(ls)5 - http://flybase.org/reports/FBgn0086203 gene - - - S(ls)5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024314 Plap Phospholipase A2 activator protein http://flybase.org/reports/FBgn0024314 FBgn0031316 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000457424 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000457424 ubiquitin homeostasis ; GO:0010992 | inferred from biological aspect of ancestor with PANTHER:PTN000457424 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000457424 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000457424 "CG5105, dPLAP, dmPLAP, Plap, plap, UFD3" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR013535:PUL domain, IPR020472:G-protein beta WD-40 repeat, IPR015155:PLAA family ubiquitin binding, PFU, IPR019775:WD40 repeat, conserved site, IPR011989:Armadillo-like helical, IPR011042:Six-bladed beta-propeller, TolB-like, IPR033510:PLAA/Doa1/Lub1" CG5105 11-Aug-17 DroID_v2017_08 Drer\plaa Scer\DOA1 Cele\ufd-3 Xtro\plaa Mmus\Plaa Hsap\PLAA "viable,fertile" FBgn0065406 l(2)SH1580 lethal (2) SH1580 http://flybase.org/reports/FBgn0065406 gene - - - "l(2)SH1580, l(2)SH2 1580" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265073 CR44184 - http://flybase.org/reports/FBgn0265073 non_protein_coding_gene - - - CR44184 - CR44184 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086912 mbm mushroom body miniature http://flybase.org/reports/FBgn0086912 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 mushroom body development ; GO:0016319 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from direct assay learning ; GO:0007612 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from direct assay olfactory learning ; GO:0008355 | traceable author statement ribosomal small subunit biogenesis ; GO:0042274 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "mbm, CG11604, mus" "IPR001878:Zinc finger, CCHC-type" CG11604 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051071 tRNA:Gln-TTG-1-2 transfer RNA:Glutamine-TTG 1-2 http://flybase.org/reports/FBgn0051071 tRNA_gene CAA codon-amino acid adaptor activity ; GO:0033427 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033427 cytosol ; GO:0005829 | inferred by curator from GO:0033427 "AE002708.trna35-GlnTTG, tRNA:Q:TTG:AE002708-b, CR31071, chr3R.trna41-GlnTTG, tRNA:Gln-TTG-1-2, tRNA:CR31071, tRNA-Gln-TTG-1-2, CAA" - CR31071 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005120 l(1)m lethal (1) malignant http://flybase.org/reports/FBgn0005120 - gene - - - "l-mal, l(1)m" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,melanotic mass phenotype" melanotic mass FBgn0036195 Dnai2 "dynein, axonemal, intermediate chain 2" http://flybase.org/reports/FBgn0036195 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:Q9GZS0 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype response to auditory stimulus ; GO:0010996 | inferred from mutant phenotype outer dynein arm assembly ; GO:0036158 | inferred from mutant phenotype sperm competition ; GO:0046692 | inferred from mutant phenotype outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q9GZS0 dendrite ; GO:0030425 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "CG6053, Dnai2" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG6053 11-Aug-17 DroID_v2017_08 "Drer\dnai2b, Drer\dnai2a" - Cele\prp-17 Xtro\dnai2 Mmus\Dnaic2 Hsap\DNAI2 "auditory perception defective,neurophysiology defective,viable" FBgn0085219 CG34190 - http://flybase.org/reports/FBgn0085219 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34190 - CG34190 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264566 CG43938 - http://flybase.org/reports/FBgn0264566 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43938 - CG43938 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040767 CG13233 - http://flybase.org/reports/FBgn0040767 protein_coding_gene - - - CG13233 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011693 Pdh Photoreceptor dehydrogenase http://flybase.org/reports/FBgn0011693 - protein_coding_gene alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from electronic annotation with InterPro:IPR002424 retinol dehydrogenase activity ; GO:0004745 | inferred from mutant phenotype oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002424 retinol metabolic process ; GO:0042572 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype retinal metabolic process ; GO:0042574 | inferred from mutant phenotype - "pcdr, CG4899, Pdh, pdh, PDH" "IPR002424:Alcohol dehydrogenase, insect-type, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site, IPR002347:Short-chain dehydrogenase/reductase SDR" CG4899 11-Aug-17 DroID_v2017_08 "Drer\zgc:56585, Drer\hpgd, Drer\cbr4" "Scer\SPS19, Scer\YDL114W" "Cele\T01G6.10, Cele\C06B8.3, Cele\T01G6.1, Cele\W03F9.9, Cele\R05D8.9, Cele\C01G12.5" Xtro\hpgd "Mmus\Cbr4, Mmus\Hpgd" "Hsap\CBR4, Hsap\HPGD" "viable,fertile,neurophysiology defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" rhabdomere FBgn0033042 Tsp42A Tetraspanin 42A http://flybase.org/reports/FBgn0033042 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008952 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG14468, Dm.Tsp42A, Tsp42A" "IPR008952:Tetraspanin, EC2 domain" CG14468 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032210 CYLD Cylindromatosis http://flybase.org/reports/FBgn0032210 protein_coding_gene Lys63-specific deubiquitinase activity ; GO:0061578 | inferred from direct assay thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype protein K63-linked deubiquitination ; GO:0070536 | inferred from biological aspect of ancestor with PANTHER:PTN000931062 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype regulation of innate immune response ; GO:0045088 | inferred from mutant phenotype protein K63-linked deubiquitination ; GO:0070536 | inferred from direct assay stress-activated protein kinase signaling cascade ; GO:0031098 | inferred from mutant phenotype protein linear deubiquitination ; GO:1990108 | inferred from direct assay acylglycerol homeostasis ; GO:0055090 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000216320 "CG5603, CYLD, dCYLD, Cyld, Q8IPC5, cyld" "IPR000938:CAP Gly-rich domain, IPR028889:Ubiquitin specific protease domain, IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase" CG5603 11-Aug-17 DroID_v2017_08 "Drer\cyldb, Drer\si:cabz01101003.1, Drer\cylda, Drer\cyldl" "Scer\RPS1A, Scer\RPS1B" Cele\cyld-1 Xtro\cyld Mmus\Cyld Hsap\CYLD "viable,fertile,short lived,recessive,oxidative stress response defective,visible,immune response defective,locomotor behavior defective" "scutellum,adult fat body,lipid particle,lipid particle | supernumerary" FBgn0263624 CR43633 - http://flybase.org/reports/FBgn0263624 non_protein_coding_gene - - - CR43633 - CR43633 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085305 CG34276 - http://flybase.org/reports/FBgn0085305 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG34276, CG5470" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG34276 11-Aug-17 DroID_v2017_08 "Drer\spint1b, Drer\spint2, Drer\spint1a" - "Cele\tag-290, Cele\mec-1, Cele\mec-9" - "Mmus\Spint3, Mmus\Spint5, Mmus\Spint2" "Hsap\SPINT2, Hsap\SPINT3" viable FBgn0034937 fzr2 fizzy-related 2 http://flybase.org/reports/FBgn0034937 protein_coding_gene anaphase-promoting complex binding ; GO:0010997 | inferred from electronic annotation with InterPro:IPR033010 ubiquitin-protein transferase activator activity ; GO:0097027 | inferred from electronic annotation with InterPro:IPR033010 molecular_function ; GO:0003674 | no biological data available positive regulation of ubiquitin protein ligase activity ; GO:1904668 | inferred from electronic annotation with InterPro:IPR033010 exit from mitosis ; GO:0010458 | NOT inferred from expression pattern male meiosis ; GO:0007140 | inferred from expression pattern anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from genetic interaction with fzr cellular_component ; GO:0005575 | no biological data available "CG16783, fzr2, FZR2" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR033010:The WD repeat Cdc20/Fizzy family, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG16783 11-Aug-17 DroID_v2017_08 "Drer\cdc20, Drer\fzr1a, Drer\fzr1b" "Scer\CDC20, Scer\CDH1, Scer\AMA1" Cele\fzr-1 "Xtro\cdc20, Xtro\fzr1" "Mmus\Fzr1, Mmus\Cdc20b, Mmus\Cdc20" "Hsap\FZR1, Hsap\CDC20B, Hsap\CDC20" " adult stage , pupal stage&&adult stage " " spermatocyte

, testis

" viable FBgn0267203 CR45643 - http://flybase.org/reports/FBgn0267203 non_protein_coding_gene - - - CR45643 - CR45643 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265743 CR44550 - http://flybase.org/reports/FBgn0265743 non_protein_coding_gene - - - CR44550 - CR44550 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024760 EC7 EC7 http://flybase.org/reports/FBgn0024760 - gene - - - EC7 - - 11-Aug-17 DroID_v2017_08 - - - - - - enhancer of variegation FBgn0030701 CG16952 - http://flybase.org/reports/FBgn0030701 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG16952 "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR011705:BTB/Kelch-associated" CG16952 11-Aug-17 DroID_v2017_08 Drer\btbd7 - Cele\C39F7.5 Xtro\btbd7 Mmus\Btbd7 Hsap\BTBD7 "viable,fertile" FBgn0264961 CR44130 - http://flybase.org/reports/FBgn0264961 non_protein_coding_gene - - - CR44130 - CR44130 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026730 aos::sty argos::sty http://flybase.org/reports/FBgn0026730 - engineered_fusion_gene - - - "argos::sty, aos::sty" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010473 tutl turtle http://flybase.org/reports/FBgn0010473 "FBgn0004699, FBgn0031593, FBgn0031594, FBgn0031595" protein_coding_gene protein binding involved in cell-cell adhesion ; GO:0098632 | inferred from physical interaction with bdl R7 cell development ; GO:0045467 | inferred from mutant phenotype inferred from genetic interaction with bdl adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype dendrite self-avoidance ; GO:0070593 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype axonal defasciculation ; GO:0007414 | inferred from mutant phenotype larval behavior ; GO:0030537 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0098632 "jf4, CT35490, CT35489, l(2)01085, l(2)jf4, l(2)24Df, CG15428, CG15426, CG15427, tutl, Tutl, mdcds_7441" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG15427 11-Aug-17 DroID_v2017_08 "Drer\sdk1a, Drer\lrit3a, Drer\kirrela, Drer\ush2a, Drer\kirrelb, Drer\igsf9ba, Drer\sdk1b, Drer\igsf9bb, Drer\lrit1b, Drer\kirrel3l, Drer\igsf9a, Drer\itgb4, Drer\lrit3b, Drer\igsf9b, Drer\kirrel3a, Drer\ncam1b, Drer\dscama, Drer\paplna, Drer\kirrel3b, Drer\si:ch1073-459j12.1, Drer\lrit1a" - Cele\igcm-2 "Xtro\kirrel2, Xtro\mdga2, Xtro\lrit3, Xtro\papln, Xtro\igsf9b, Xtro\igsf9" "Mmus\Lrit3, Mmus\Sdk1, Mmus\Igsf9b, Mmus\Kirrel2, Mmus\Mdga2, Mmus\Kirrel, Mmus\Igsf9, Mmus\Lrit1, Mmus\Kirrel3, Mmus\Ptprq, Mmus\Mdga1, Mmus\Papln" "Hsap\SDK1, Hsap\PAPLN, Hsap\KIRREL2, Hsap\IGSF9B, Hsap\IGSF9, Hsap\MDGA1, Hsap\USH2A, Hsap\KIRREL, Hsap\LRIT1, Hsap\KIRREL3, Hsap\LRIT3, Hsap\MDGA2" "touch sensitivity defective,neuroanatomy defective,somatic clone,partially lethal - majority live,behavior defective,recessive,flightless,lethal,partially lethal - majority die,some die during pupal stage,locomotor behavior defective,viable,visible,lethal - all die before end of pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "dendrite & dorsal multidendritic neuron ddaE,dendrite & dorsal multidendritic neuron ddaC,dendrite & dorsal multidendritic neuron ddaEed-dp),dendrite & dorsal multidendritic neuron ddaE | somatic clone,dendrite & dorsal multidendritic neuron ddaC | somatic clone,photoreceptor cell R7,intersegmental nerve branch ISNb of A1-7,intersegmental nerve branch ISNd of A1-7,optic chiasma,lateral medial fascicle,ventral nerve cord commissure,medial longitudinal fascicle,intermediate longitudinal fascicle,lateral longitudinal fascicle,midline crossing tract,somatic clone,photoreceptor cell R8,dendrite & dorsal multidendritic neuron ddaCppk.1.9,chaeta,supernumerary,mesothoracic tergum,longitudinal connective,commissure,transverse nerve,optic lobe,neuropil" DRSC00442 I 1.685338574 0.820241912 -0.400300591 -0.139576424 -0.046393783 0.060334327 FBgn0011259 Sema1a Semaphorin 1a http://flybase.org/reports/FBgn0011259 "FBgn0021877, FBgn0063028" protein_coding_gene semaphorin receptor binding ; GO:0030215 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with PlexA heparin binding ; GO:0008201 | inferred from direct assay axon guidance ; GO:0007411 | inferred from direct assay axon guidance ; GO:0007411 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance ; GO:2000305 | inferred from genetic interaction with Rho1 inferred from genetic interaction with PlexA synapse assembly ; GO:0007416 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "Sema1a, sema1a, SemaI, Sema1A, Sema 1a, sema-1a, CG18405, CT26404, Dsema-I, sema-I, D-Sema 1a, Sema-I, D-SemaI, d-semaI, d-sema I, FasIV, D-semaI, D-Sema I, l(2)k13702, Fas-IV, D-Sema-I, BcDNA:RE36155, Sema-1a, sema, SEMA-1A, sema 1a, Dsema 1a" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001627:Sema domain, IPR002165:Plexin repeat, IPR016201:PSI domain, IPR027231:Semaphorin" CG18405 11-Aug-17 DroID_v2017_08 "Drer\sema3aa, Drer\sema4d, Drer\sema4c, Drer\sema4gb, Drer\si:ch211-113g11.6, Drer\sema4ga, Drer\sema4e, Drer\sema3ab, Drer\sema3h, Drer\LOC798168, Drer\sema3e, Drer\si:dkey-49n23.1, Drer\sema4ab, Drer\sema3fb, Drer\sema6bb, Drer\sema6e, Drer\sema5a, Drer\sema4ba, Drer\sema5bb, Drer\sema3fa, Drer\sema3gb, Drer\sema6d, Drer\rttn, Drer\sema3d, Drer\sema3c, Drer\sema3bl, Drer\sema5ba, Drer\si:ch211-129c21.1, Drer\sema6dl, Drer\sema6a, Drer\sema7a, Drer\si:ch211-168n16.1, Drer\sema3ga" - "Cele\smp-2, Cele\mab-20, Cele\F23H12.5, Cele\smp-1" "Xtro\sema4a, Xtro\sema4c, Xtro\sema6a, Xtro\sema5b, Xtro\sema4d, Xtro\sema3a, Xtro\sema3d, Xtro\sema3c, Xtro\sema4b, Xtro\sema6b, Xtro\sema6d, Xtro\sema3f, Xtro\sema4g, Xtro\sema3b" "Mmus\Sema4f, Mmus\Sema5b, Mmus\Sema6c, Mmus\Sema5a, Mmus\Sema3g, Mmus\Sema3b, Mmus\Sema3d, Mmus\Sema3e, Mmus\Sema6d, Mmus\Sema4b, Mmus\Sspo, Mmus\Sema3a, Mmus\Sema4a, Mmus\Sema3c, Mmus\Sema3f, Mmus\Sema6a, Mmus\Sema7a, Mmus\Sema4g, Mmus\Sema6b, Mmus\Sema4d" "Hsap\SEMA4F, Hsap\SEMA3D, Hsap\SEMA7A, Hsap\SEMA3C, Hsap\SEMA4A, Hsap\SEMA4G, Hsap\SEMA6B, Hsap\SEMA5B, Hsap\SEMA3E, Hsap\SEMA6A, Hsap\SEMA6D, Hsap\SEMA3A, Hsap\SEMA4C, Hsap\SEMA3F, Hsap\SEMA5A, Hsap\SEMA4B, Hsap\SEMA3G, Hsap\SEMA4D, Hsap\SEMA6C" embryonic stage " central nervous system

, embryonic peripheral nervous system

, sense organ | lateral

, embryonic neuron

" "viable,lethal,recessive,partially lethal - majority die,neuroanatomy defective,somatic clone,cell non-autonomous,heat sensitive,neurophysiology defective,some die during pupal stage" "segmental nerve,intersegmental nerve,synapse,synapse | ectopic,abdominal ventral longitudinal muscle & synapse,transverse nerve,longitudinal connective,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina,lateral longitudinal fascicle,RP3 neuron & synapse,RP5 neuron & synapse,presumptive embryonic/larval central nervous system,axon & beta'-lobe | somatic clone,axon & alpha'-lobe | somatic clone,axon & antennal glomerulus DL1 | somatic clone | cell autonomous,dendrite & antennal glomerulus DL1 | somatic clone,dendrite & antennal glomerulus DA1 | somatic clone,dendrite & antennal glomerulus DC3 | somatic clone,axon & antennal glomerulus DA1 | somatic clone,axon & antennal glomerulus DC3 | somatic clone,axon & antennal glomerulus VM2 | somatic clone,adult olfactory receptor neuron Or33c/85e,cell non-autonomous,somatic clone,adult olfactory receptor neuron Or46a,adult olfactory receptor neuron Or42a,adult olfactory receptor neuron Or59c,axon & eye photoreceptor cell,eye photoreceptor cell & lamina,axon & lamina,axon & eye photoreceptor cell | somatic clone | cell autonomous,axon & lamina | somatic clone | somatic clone | cell autonomous,eye photoreceptor cell & lamina | somatic clone | cell autonomous,abdominal segmental nerve,adult olfactory receptor neuron Or71a,adult olfactory receptor neuron Or43a,adult olfactory receptor neuron Or83c,adult olfactory receptor neuron Or88a,adult olfactory receptor neuron Or23a,adult olfactory receptor neuron Or35a,adult olfactory receptor neuron Or67b,adult olfactory receptor neuron Or47b,eye photoreceptor cell,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,posterior commissure,anterior commissure,posterior commissure | embryonic stage,axon & eye photoreceptor cellN22-5),eye photoreceptor cell & laminaN22-5),axon & laminaN22-5),abdominal intersegmental nerve,ventral nerve cord,motor neuron,giant fiber neuron,heat sensitive,intersegmental nerve | embryonic stage,segmental nerve | embryonic stage,dendrite & antennal glomerulus | somatic cloneGH146,axon & eye photoreceptor cellGMR.PF,axon & laminaGMR.PF,eye photoreceptor cell & laminaGMR.PF,axon & medullaGMR.PF,eye photoreceptor cell & medullaGMR.PF,nerve terminal & lamina plexusGMR.PF,eye photoreceptor cell | third instar larval stage,lamina | third instar larval stage,photoreceptor cell R1 & lamina,photoreceptor cell R2 & lamina,photoreceptor cell R3 & lamina,photoreceptor cell R4 & lamina,photoreceptor cell R5 & lamina,photoreceptor cell R7 & lamina" FBgn0034396 CG15097 - http://flybase.org/reports/FBgn0034396 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 - Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from biological aspect of ancestor with PANTHER:PTN001973695 "Dm.CG15097, CG15097" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011705:BTB/Kelch-associated, IPR011043:Galactose oxidase/kelch, beta-propeller, IPR011333:SKP1/BTB/POZ domain, IPR017096:BTB-kelch protein, IPR015915:Kelch-type beta propeller, IPR015916:Galactose oxidase, beta-propeller" CG15097 11-Aug-17 DroID_v2017_08 "Drer\klhl17, Drer\klhl20, Drer\klhl12, Drer\klhl18, Drer\klhl5, Drer\klhl3, Drer\klhl2" - "Cele\kel-1, Cele\kel-3, Cele\R12E2.1" "Xtro\klhl5, Xtro\klhl20, Xtro\klhl12, Xtro\klhl17, Xtro\klhl4" "Mmus\Klhl20, Mmus\Klhl5, Mmus\Klhl12, Mmus\Klhl17, Mmus\Klhl4, Mmus\Klhl18, Mmus\Klhl3, Mmus\Klhl2, Mmus\Klhl1" "Hsap\KLHL17, Hsap\KLHL18, Hsap\KLHL1, Hsap\KLHL20, Hsap\KLHL2, Hsap\KLHL4, Hsap\KLHL3, Hsap\KLHL5, Hsap\KLHL12" viable FBgn0259340 C839 - http://flybase.org/reports/FBgn0259340 gene - - - C839 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing hair,chaeta,ectopic" FBgn0032883 Rhau RHAU helicase http://flybase.org/reports/FBgn0032883 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 ATP-dependent DNA helicase activity ; GO:0004003 | inferred from direct assay G-quadruplex RNA binding ; GO:0002151 | inferred from direct assay ATP-dependent RNA helicase activity ; GO:0004004 | inferred from direct assay helicase activity ; GO:0004386 | inferred from sequence or structural similarity" G-quadruplex DNA unwinding ; GO:0044806 | inferred from direct assay RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "38E.15, cg9323, CG9323, Rhau, DmRHAU" "IPR001650:Helicase, C-terminal, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR011545:DEAD/DEAH box helicase domain" CG9323 11-Aug-17 DroID_v2017_08 "Drer\tdrd9, Drer\dhx57, Drer\dhx29, Drer\dhx9, Drer\dhx30, Drer\dhx36" Scer\YLR419W Cele\rha-1 "Xtro\dhx36, Xtro\ythdc2, Xtro\dhx30, Xtro\dhx9, Xtro\tdrd9, Xtro\dhx29" "Mmus\Dhx30, Mmus\Tdrd9, Mmus\Ythdc2, Mmus\Dhx29, Mmus\Dhx9, Mmus\Dhx36, Mmus\Dhx57" "Hsap\DHX36, Hsap\DHX30, Hsap\TDRD9, Hsap\YTHDC2, Hsap\DHX57, Hsap\DHX9, Hsap\DHX29" "viable,fertile,lethal" FBgn0024929 Su(var)2-b4801 Su(var)2-b4801 http://flybase.org/reports/FBgn0024929 - gene - - - "Su-var(2)b4801, Su(var)2-b4801" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266449 Kr-h2 Kruppel homolog 2 http://flybase.org/reports/FBgn0266449 protein_coding_gene structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN001398562 nuclear pore complex assembly ; GO:0051292 | inferred from biological aspect of ancestor with PANTHER:PTN001398562 endoplasmic reticulum tubular network organization ; GO:0071786 | inferred from biological aspect of ancestor with PANTHER:PTN001398562 cellular protein localization ; GO:0034613 | inferred from biological aspect of ancestor with PANTHER:PTN001398562 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005344 endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN001398562 nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN001398562 "Kr-h2, CG9159, Kr-h, Kr-H2, anon-26Ba" IPR005344:Per33/Pom33 family CG9159 11-Aug-17 DroID_v2017_08 Drer\tmem33 "Scer\MND1, Scer\POM33, Scer\YGR026W, Scer\PER33" Cele\Y37D8A.17 Xtro\tmem33 Mmus\Tmem33 Hsap\TMEM33 FBgn0017378 l(1)HM409 lethal (1) HM409 http://flybase.org/reports/FBgn0017378 - gene - - - l(1)HM409 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030614 CG9072 - http://flybase.org/reports/FBgn0030614 protein_coding_gene beta-tubulin binding ; GO:0048487 | inferred from electronic annotation with InterPro:IPR004226 tubulin complex assembly ; GO:0007021 | inferred from electronic annotation with InterPro:IPR004226 post-chaperonin tubulin folding pathway ; GO:0007023 | inferred from electronic annotation with InterPro:IPR004226 - CG9072 IPR004226:Tubulin binding cofactor A CG9072 11-Aug-17 DroID_v2017_08 Drer\tbca Scer\RBL2 Cele\tbca-1 Xtro\tbca Mmus\Tbca Hsap\TBCA lethal FBgn0022306 l(1)L25.7 lethal (1) L25.7 http://flybase.org/reports/FBgn0022306 - gene - - - "L25.7, l(1)L25.7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263531 mir-4955 mir-4955 stem loop http://flybase.org/reports/FBgn0263531 miRNA_gene - - - "mir-4955, dme-mir-4955, CR43516" - CR43516 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023166 Su(mg)1-1 Suppressor of modifier of gypsy 1-1 http://flybase.org/reports/FBgn0023166 - gene - - - Su(mg)1-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267578 CR45918 - http://flybase.org/reports/FBgn0267578 non_protein_coding_gene - - - "CR45918, pri-mir-987" - CR45918 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034716 Oatp58Dc Organic anion transporting polypeptide 58Dc http://flybase.org/reports/FBgn0034716 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with Oatp58Db active transmembrane transporter activity ; GO:0022804 | inferred from sequence or structural similarity with Oatp58Db organic substance transport ; GO:0071702 | inferred from sequence or structural similarity with Oatp58Db response to toxic substance ; GO:0009636 | inferred from expression pattern renal tubular secretion ; GO:0097254 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Oatp58Db basolateral plasma membrane ; GO:0016323 | inferred from direct assay "oatp 58Dc, CG3380, Oatp58Dc, OATP, OATP58Dc" "IPR020846:Major facilitator superfamily domain, IPR004156:Organic anion transporter polypeptide OATP, IPR002350:Kazal domain" CG3380 11-Aug-17 DroID_v2017_08 "Drer\slco1c1, Drer\LOC100334356, Drer\slco5a1, Drer\slco4a1, Drer\slco2a1, Drer\slco1d1, Drer\slco1f1, Drer\slco2b1, Drer\LOC101883455, Drer\slco1f3, Drer\LOC100536648, Drer\slco1f4, Drer\LOC570448, Drer\slco3a1, Drer\slco1f2" - "Cele\F47E1.4, Cele\F47E1.2, Cele\K02G10.5, Cele\F53B1.8, Cele\Y70G10A.3, Cele\Y32F6B.1, Cele\F21G4.1" "Xtro\slco3a1, Xtro\slco4c1, Xtro\slco1b3, Xtro\slco2a1, Xtro\slco4a1, Xtro\slco5a1" "Mmus\Slco5a1, Mmus\Slco4a1, Mmus\Slco2b1, Mmus\Slco6c1, Mmus\Gm5724, Mmus\Slco6d1, Mmus\Slco1a6, Mmus\Slco4c1, Mmus\Slco1c1, Mmus\Slco1a5, Mmus\Slco2a1, Mmus\Gm6614, Mmus\Slco1b2, Mmus\Slco3a1, Mmus\Slco1a1, Mmus\Slco1a4" "Hsap\SLCO4C1, Hsap\SLCO2A1, Hsap\SLCO5A1, Hsap\SLCO1B7, Hsap\SLCO1A2, Hsap\SLCO2B1, Hsap\SLCO1B1, Hsap\SLCO6A1, Hsap\SLCO3A1, Hsap\SLCO4A1, Hsap\SLCO1C1, Hsap\SLCO1B3" viable FBgn0040206 krz kurtz http://flybase.org/reports/FBgn0040206 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Ulp1 locomotory exploration behavior ; GO:0035641 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from mutant phenotype negative regulation of inflammatory response ; GO:0050728 | inferred from mutant phenotype gastrulation ; GO:0007369 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from mutant phenotype negative regulation of protein tyrosine kinase activity ; GO:0061099 | inferred from genetic interaction with rl positive regulation of protein desumoylation ; GO:0060189 | inferred from genetic interaction with Ulp1 instar larval development ; GO:0002168 | inferred from mutant phenotype negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype inferred from genetic interaction with dx inferred from genetic interaction with N negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "0952/14, l(3)S095214, CG1487, krz, Krz, Kurz, kurtz" "IPR000698:Arrestin, IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014753:Arrestin, N-terminal, IPR014756:Immunoglobulin E-set, IPR017864:Arrestin, conserved site" CG1487 11-Aug-17 DroID_v2017_08 "Drer\arrb1, Drer\arr3b, Drer\sagb, Drer\arr3a, Drer\arrb2b, Drer\saga, Drer\arrb2a" - Cele\arr-1 "Xtro\arrb1, Xtro\arr3, Xtro\arrb2, Xtro\sag" "Mmus\Arr3, Mmus\Sag, Mmus\Arrb2, Mmus\Arrb1" "Hsap\ARR3, Hsap\ARRB2, Hsap\ARRB1, Hsap\SAG" " adult stage && oogenesis stage , larval stage | third instar , adult stage , embryonic stage , embryonic stage | stage 17 , embryonic stage | stage 16 , embryonic stage | stage <=8 , embryonic stage -- adult stage " " nurse cell

, larval deuterocerebrum

, ventral nerve cord | ventral

, oocyte

, cirri

, embryonic central nervous system

, embryonic/larval fat body

, dorsal pouch

, eye-antennal disc

, antennal sense organ

, organism | ubiquitous

, cephalopharyngeal skeleton

, dorsal mesothoracic disc | restricted

, embryonic/larval trachea

" "visible,somatic clone,melanotic mass phenotype,recessive,increased cell death,size defective,lethal - all die before end of larval stage,some die during third instar larval stage,sterile,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,locomotor behavior defective,viable,wild-type" "wing blade,somatic clone,imaginal disc,wing vein,1st posterior cell,ectopic,macrochaeta,melanotic mass,embryonic/larval fat body,lamellocyte,embryonic/first instar larval cuticle,presumptive embryonic/larval nervous system" FBgn0000664 fle femaleless http://flybase.org/reports/FBgn0000664 - gene - - - "fle(3)100, file(3)100, fle" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female,viable,male" FBgn0034721 CG11298 - http://flybase.org/reports/FBgn0034721 protein_coding_gene - regulation of microtubule polymerization or depolymerization ; GO:0031110 | inferred from electronic annotation with InterPro:IPR000956 - "BcDNA:AT10824, CG11298" IPR000956:Stathmin family CG11298 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0266517 s-563.2 - http://flybase.org/reports/FBgn0266517 gene - - - s-563.2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002514 l(3)Sp6 lethal (3) Sp6 http://flybase.org/reports/FBgn0002514 - gene - - - l(3)Sp6 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0015354 anon-99Cc anon-99Cc http://flybase.org/reports/FBgn0015354 - gene - - - anon-99Cc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039588 mIF2 mitochondrial translation initiation factor 2 http://flybase.org/reports/FBgn0039588 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR005225 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000005383 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000005383 tRNA binding ; GO:0000049 | inferred from sequence or structural similarity with SGD:S000005383 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with UniProtKB:P46199" translational initiation ; GO:0006413 | inferred from sequence or structural similarity with UniProtKB:P46199 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with SGD:S000005383 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P46199 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000005383 "CG12413, mIF2" "IPR000795:Transcription factor, GTP-binding domain, IPR005225:Small GTP-binding protein domain, IPR009000:Translation protein, beta-barrel domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR023115:Translation initiation factor IF- 2, domain 3" CG12413 11-Aug-17 DroID_v2017_08 Drer\mtif2 Scer\IFM1 Cele\F46B6.6 Xtro\mtif2 Mmus\Mtif2 Hsap\MTIF2 FBgn0031905 gudu gudu http://flybase.org/reports/FBgn0031905 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sperm individualization ; GO:0007291 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000593603 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000593603 "CG5155, gudu, Gudu" "IPR000225:Armadillo, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR026959:Armadillo repeat-containing protein 4" CG5155 11-Aug-17 DroID_v2017_08 "Drer\ctnnd2b, Drer\pkp4, Drer\ctnnd2a, Drer\rsph14, Drer\arvcfb, Drer\armc3, Drer\jupb, Drer\armc4, Drer\ankar" Scer\VAC8 "Cele\gadr-3, Cele\gadr-2, Cele\hmp-2, Cele\jac-1" "Xtro\armc4, Xtro\armc3, Xtro\ctnnb1, Xtro\rsph14, Xtro\ankar" "Mmus\Ctnnd2, Mmus\Ankar, Mmus\Ctnnb1, Mmus\Pkp4, Mmus\Arvcf, Mmus\Rsph14, Mmus\Armc3, Mmus\Armc4, Mmus\Jup" "Hsap\ARMC4, Hsap\ARMC3, Hsap\ARVCF, Hsap\ANKAR, Hsap\JUP, Hsap\PKP4, Hsap\CTNND2, Hsap\CTNNB1, Hsap\RSPH14" "viable,male sterile" "spermatozoon,spermatid,sperm individualization complextub.PU,sperm individualization complexbam.THsimVP16" FBgn0259199 Snup Snurportin http://flybase.org/reports/FBgn0259199 protein_coding_gene U1 snRNA binding ; GO:0030619 | inferred from direct assay U4 snRNA binding ; GO:0030621 | inferred from direct assay U2 snRNA binding ; GO:0030620 | inferred from direct assay - cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay Cajal body ; GO:0015030 | inferred from direct assay "CG42303, CG1247, CG32297, Snup, dSNUP" IPR015943:WD40/YVTN repeat-like-containing domain CG42303 11-Aug-17 DroID_v2017_08 Drer\snupn - Cele\F23F1.5 Xtro\snupn Mmus\Snupn Hsap\SNUPN FBgn0014229 l(2)31Ej lethal (2) 31Ej http://flybase.org/reports/FBgn0014229 - gene - - - l(2)31Ej - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0045073 Stim Stromal interaction molecule http://flybase.org/reports/FBgn0045073 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN001031746 store-operated calcium channel activity ; GO:0015279 | inferred from mutant phenotype calcium channel regulator activity ; GO:0005246 | inferred from biological aspect of ancestor with PANTHER:PTN001031746 calcium-induced calcium release activity ; GO:0048763 | inferred from mutant phenotype calcium ion binding ; GO:0005509 | inferred from direct assay chaeta development ; GO:0022416 | inferred from mutant phenotype detection of calcium ion ; GO:0005513 | inferred from direct assay activation of store-operated calcium channel activity ; GO:0032237 | inferred from mutant phenotype store-operated calcium entry ; GO:0002115 | inferred from mutant phenotype regulation of calcium ion transport ; GO:0051924 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001031746 integral component of membrane ; GO:0016021 | non-traceable author statement endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN001031746 "D-Stim, CG9126, D-STIM, Stim, dStim, STIM, stim1, C-Stim, dstim, dSTIM, STIM1" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain, IPR032393:Stromal interaction molecule, Orai1-activating region" CG9126 11-Aug-17 DroID_v2017_08 "Drer\stim2b, Drer\stim1b, Drer\kif5c, Drer\stim1a, Drer\stim2a" Scer\NST1 "Cele\T07C4.10, Cele\stim-1" "Xtro\stim2, Xtro\stim1" "Mmus\Stim2, Mmus\Stim1" "Hsap\STIM2, Hsap\STIM1, Hsap\SYCP1" "visible,increased cell death,hypoactive,lethal - all die before end of larval stage,some die during larval stage,lethal,viable" "posterior wing margin,anterior wing margin,embryonic/larval fat body,mesothoracic tergum,microchaeta & mesothoracic tergumpnr-MD237,wing vein,eye,ommatidium,interommatidial bristle,microchaeta,wing margin bristle,ectopic,wing vein L5,distal,wing,wing hair,sensillum campaniformium,wing disc,S2 cell-line,trichogen cell,supernumerary" FBgn0085580 CG41254 - http://flybase.org/reports/FBgn0085580 protein_coding_gene - - - CG41254 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030243 CG2186 - http://flybase.org/reports/FBgn0030243 protein_coding_gene - - - CG2186 - CG2186 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-150e22.5, Drer\rbm33b" - - Xtro\rbm33 Mmus\Rbm33 Hsap\RBM33 "viable,fertile" DRSC19838 I 1.657352386 -0.836288979 1.092989747 -0.587815437 0.934306152 -0.253974705 FBgn0028506 CG4455 - http://flybase.org/reports/FBgn0028506 protein_coding_gene - - - "BG:DS09218.3, LD27171, BEST:LD27171, CG4455" - CG4455 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,female fertile,visible,partially lethal - majority die" "eye,macrochaeta" FBgn0000866 fs(1)M61 female sterile (1) M61 http://flybase.org/reports/FBgn0000866 - gene - - - fs(1)M61 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083254 E(smoDN)B-right Enhancer of smoDN group B-right http://flybase.org/reports/FBgn0083254 gene - smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "Group B-right, E(smoDN)B-right" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethalcell lethal,somatic clone" FBgn0031861 CG17375 - http://flybase.org/reports/FBgn0031861 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 CG17375 - CG17375 11-Aug-17 DroID_v2017_08 - - "Cele\anat-1, Cele\T10B5.4" - - - viable FBgn0013688 mt:srRNA mitochondrial small ribosomal RNA http://flybase.org/reports/FBgn0013688 "FBgn0002867, FBgn0025234" rRNA_gene - pole cell formation ; GO:0007279 | traceable author statement P granule ; GO:0043186 | traceable author statement P granule ; GO:0043186 | colocalizes_with inferred from direct assay "CR34096, mtsrRNA, 12S rRNA, msrRNA, 12S, mtrRNA, anon-EST:fe2A4, mt:srRNA, 12 S rRNA, srRNA, rRNA-12s, rRNA-12 S, snRNA-d, SSU rRNA" - CR34096 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | stage 1-3 pole granule

FBgn0051805 CG31805 - http://flybase.org/reports/FBgn0051805 protein_coding_gene molecular_function ; GO:0003674 | no biological data available wound healing ; GO:0042060 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG31805 - CG31805 11-Aug-17 DroID_v2017_08 - - Cele\Y6B3B.4 - - Hsap\C2orf16 viable FBgn0020643 Lcp65Ab2 Lcp65Ab2 http://flybase.org/reports/FBgn0020643 "FBgn0002536, FBgn0042114, FBgn0047112" protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence or structural similarity structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Lcp-b, Lcp65A-b, Lcp65Ab, Lcp-b2, LCP5, LCP-5, L[[3]]CP5, CP5, Lcp5, DCP-beta, CG18773, BcDNA:RE39879, Lcp65Ab2, LCP65Ab2" IPR000618:Insect cuticle protein CG18773 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\math-34, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - " larval stage , embryonic stage " FBgn0043467 064Ya 064Ya http://flybase.org/reports/FBgn0043467 gene molecular_function ; GO:0003674 | no biological data available behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 064Ya - - 11-Aug-17 DroID_v2017_08 - - - - - - chemical sensitive FBgn0024897 b6 b6 http://flybase.org/reports/FBgn0024897 FBgn0025380 protein_coding_gene - - - "CG3100, EG:9D2.1, b6, B6" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001759:Pentraxin-related" CG3100 11-Aug-17 DroID_v2017_08 "Drer\zgc:136389, Drer\crp3, Drer\crp1, Drer\crp2, Drer\ca6, Drer\crp6, Drer\crp7, Drer\crp, Drer\si:ch211-234p6.10, Drer\crp4" - - Xtro\nptx2 "Mmus\Crp, Mmus\Apcs, Mmus\Mptx2, Mmus\Nptx2" "Hsap\CRP, Hsap\APCS, Hsap\NPTX2" "viable,visible" mesothoracic tergum FBgn0266208 CR44903 - http://flybase.org/reports/FBgn0266208 non_protein_coding_gene - - - CR44903 - CR44903 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037042 CG12984 - http://flybase.org/reports/FBgn0037042 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12984 - CG12984 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0015714 Cyp6a17 Cytochrome P450-6a17 http://flybase.org/reports/FBgn0015714 FBgn0033977 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 thermosensory behavior ; GO:0040040 | inferred from mutant phenotype" - "Cyp6a17, cyp6a17, 6a17, 61D6S, ESTS:61D6S, CG10241, Cyp6A17" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10241 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp3c3, Drer\tbxas1, Drer\cyp3c2, Drer\cyp4t8, Drer\cyp3c4, Drer\cyp4v8, Drer\cyp2p10, Drer\cyp3c1, Drer\cyp4v7, Drer\cyp4f3" "Scer\ERG11, Scer\DIT2" "Cele\cyp-13A4, Cele\cyp-29A4, Cele\cyp-42A1, Cele\cyp-43A1, Cele\cyp-31A2, Cele\cyp-13A3, Cele\cyp-31A3, Cele\cyp-25A2, Cele\cyp-44A1, Cele\cyp-13A7, Cele\cyp-25A3, Cele\cyp-32A1, Cele\cyp-32B1, Cele\cyp-25A6, Cele\cyp-13A8, Cele\cyp-25A4, Cele\cyp-13B2, Cele\cyp-13A1, Cele\cyp-37B1, Cele\cyp-13A2, Cele\cyp-13A11, Cele\cyp-13A5, Cele\cyp-13B1, Cele\cyp-13A12, Cele\cyp-29A3, Cele\cyp-29A2, Cele\cyp-13A10, Cele\cyp-13A6, Cele\cyp-25A1" "Xtro\cyp3a4, Xtro\cyp3a5, Xtro\LOC100494419, Xtro\tbxas1" "Mmus\Cyp4f13, Mmus\Tbxas1, Mmus\Cyp4f18, Mmus\Cyp3a11, Mmus\Cyp4a12a, Mmus\Cyp3a59, Mmus\Cyp4f15, Mmus\Cyp3a25, Mmus\Cyp3a44, Mmus\Cyp4a32, Mmus\Cyp3a57, Mmus\Cyp4v3, Mmus\Cyp4f17, Mmus\Cyp4b1, Mmus\Cyp4f39, Mmus\Cyp4a14, Mmus\Cyp3a13, Mmus\Cyp4a12b, Mmus\Cyp3a41a, Mmus\Cyp4a10, Mmus\Cyp4f14, Mmus\Cyp3a41b, Mmus\Cyp3a16, Mmus\Cyp4f37, Mmus\Cyp4f16, Mmus\Cyp4a31" "Hsap\CYP4F22, Hsap\CYP4B1, Hsap\TBXAS1, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4X1, Hsap\CYP4F12, Hsap\CYP4A11, Hsap\CYP4F3, Hsap\CYP3A5, Hsap\CYP4F11, Hsap\CYP4Z1, Hsap\CYP3A43, Hsap\CYP4V2, Hsap\CYP3A4, Hsap\CYP4A22, Hsap\CYP4F2, Hsap\CYP4F8, Hsap\CYP3A7" "temperature response defective,viable,fertile" FBgn0034292 CG5767 - http://flybase.org/reports/FBgn0034292 protein_coding_gene - - - "CT18118, CG5767" IPR007931:Protein of unknown function DUF725 CG5767 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036654 CG9692 - http://flybase.org/reports/FBgn0036654 protein_coding_gene - - - CG9692 - CG9692 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0043016 91R 91R http://flybase.org/reports/FBgn0043016 gene - - - "91R, 91-R" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267800 CR46125 - http://flybase.org/reports/FBgn0267800 non_protein_coding_gene - - - CR46125 - CR46125 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039202 CG13622 - http://flybase.org/reports/FBgn0039202 protein_coding_gene - - - CG13622 - CG13622 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0016980 snRNA:K8 small nuclear RNA K8 http://flybase.org/reports/FBgn0016980 - snRNA_gene - - - "K8, snRNA:K8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000024 Ace Acetylcholine esterase http://flybase.org/reports/FBgn0000024 - protein_coding_gene acetylcholinesterase activity ; GO:0003990 | inferred from mutant phenotype acetylcholinesterase activity ; GO:0003990 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from mutant phenotype cholinesterase activity ; GO:0004104 | inferred from direct assay acetylcholine catabolic process in synaptic cleft ; GO:0001507 | inferred from electronic annotation with InterPro:IPR001445 acetylcholine catabolic process ; GO:0006581 | inferred from direct assay acetylcholine catabolic process ; GO:0006581 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype choline catabolic process ; GO:0042426 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "ace, CG17907, AchE, AChE, DmAChE, dmAChE, FBgn0000024, dAChE, ache, CHE, ACE, AcChE, l(3)87Ed, l(3)26, Ace, ace-2, Dm_ace" "IPR000997:Cholinesterase, IPR001445:Acetylcholinesterase, insect, IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG17907 11-Aug-17 DroID_v2017_08 "Drer\LOC100334697, Drer\si:dkey-30c15.17, Drer\ache" - "Cele\ace-2, Cele\ace-3, Cele\ace-4, Cele\ace-1" "Xtro\bche, Xtro\ache" "Mmus\Ces1a, Mmus\Bche, Mmus\Ache" "Hsap\BCHE, Hsap\ACHE" "lethal,recessive,viable,fertile,neuroanatomy defective,wild-type,chemical resistant,partially lethal - majority die,phototaxis defective,heat sensitive,somatic clone,neurophysiology defective,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,non-enhancer of variegation,non-suppressor of variegation,locomotor behavior defective,electrophoretic variant,uncoordinated,suppressor of variegation,partially,optomotor response defective,visual behavior defective,courtship behavior defective,cold sensitive,mating defective,hypoactive,male,paralytic" "NMJ bouton,eye photoreceptor cell & axon & stage 2 third instar larva | somatic clone,eye photoreceptor cell & axon & stage 2 third instar larva | somatic clone | cell non-autonomous,aCC neuron,RP2 motor neuron,adult brain & neuropil | conditional ts,central nervous system,somatic clone" FBgn0030969 Usp39 Ubiquitin specific protease 39 http://flybase.org/reports/FBgn0030969 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001607 thiol-dependent ubiquitinyl hydrolase activity ; GO:0036459 | inferred from electronic annotation with InterPro:IPR001394 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence model "spliceosomal complex assembly ; GO:0000245 | inferred from electronic annotation with InterPro:IPR033809 protein deubiquitination ; GO:0016579 | inferred from electronic annotation with InterPro:IPR001394 protein deubiquitination ; GO:0016579 | inferred from sequence model mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG7288, Usp39, Q9VWP1" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR001607:Zinc finger, UBP-type, IPR033809:USP39, IPR028889:Ubiquitin specific protease domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7288 11-Aug-17 DroID_v2017_08 Drer\usp39 Scer\SAD1 Cele\usp-39 Xtro\usp39 Mmus\Usp39 Hsap\USP39 "visible,lethal,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,locomotor behavior defective,heat sensitive" "wing,wing margin bristle,scutellar bristle" DRSC20032 IEK -0.534067363 1.788545429 -1.239257427 2.267994632 2.148869973 -0.579149805 FBgn0000735 fs(1)1867 female sterile (1) 1867 http://flybase.org/reports/FBgn0000735 - gene - - - fs(1)1867 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile soma-dependent,recessive,visible,dominant" "ovariole,oocyte,follicle cell,macrochaeta" FBgn0002632 E(spl)m6-BFM "Enhancer of split m6, Bearded family member" http://flybase.org/reports/FBgn0002632 - protein_coding_gene "ubiquitin protein ligase binding ; GO:0031625 | inferred from sequence or structural similarity with E(spl)m4-BFM, E(spl)mα-BFM protein binding ; GO:0005515 | inferred from physical interaction with neur" sensory organ development ; GO:0007423 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from sequence or structural similarity with Brd cellular_component ; GO:0005575 | no biological data available "CG8354, HLHm6, E(spl)m6, M6, m6, E(spl)M6, DmelCG8354, E(spl)m6-BFM" - CG8354 11-Aug-17 DroID_v2017_08 - - - - Mmus\Gpm6a Hsap\GPM6A " larval stage | third instar , embryonic stage , embryonic stage | stage 13-15 , embryonic stage | 10-14 hr " " dorsal mesothoracic disc | restricted

, embryonic central nervous system

, ventral nerve cord

,

segmentally repeated , embryonic peripheral nervous system

, embryonic brain

, embryonic/larval midgut | restricted

" "visible,viable" "macrochaeta,microchaeta,sensory mother cell,medial triple row,chemosensory ventral triple row bristle,dorsal triple row,sensillum campaniformium of dorsal radius,wing margin,wing margin bristle" FBgn0010403 Obp83b Odorant-binding protein 83b http://flybase.org/reports/FBgn0010403 - protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "OS-E, Obp83b, 83b, PBP-H1, CG11422, obp83b, DmelObp83b, Os-E" IPR006170:Pheromone/general odorant binding protein CG11422 11-Aug-17 DroID_v2017_08 - - - - - - adult stage " antennal segment 3

, sensillum trichodeum of antennal segment 3

" "viable,fertile" FBgn0035997 phol pleiohomeotic like http://flybase.org/reports/FBgn0035997 protein_coding_gene DNA binding ; GO:0003677 | traceable author statement sequence-specific DNA binding ; GO:0043565 | inferred from direct assay gene silencing ; GO:0016458 | inferred from genetic interaction with pho nucleus ; GO:0005634 | inferred from direct assay "CG3445, phol, PHOL, Phol" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3445 11-Aug-17 DroID_v2017_08 "Drer\yy1a, Drer\yy1b" "Scer\NRG1, Scer\NRG2" Cele\ztf-17 Xtro\yy1 "Mmus\Zfp42, Mmus\Yy1, Mmus\Yy2" "Hsap\ZFP42, Hsap\YY1, Hsap\YY2" "viable,fertile,male fertile,female sterile,recessive,lethal,maternal effect,germline clone" DRSC10367 I -0.055054956 1.730562385 -0.107335836 -0.09410573 0.105551327 0.242137691 FBgn0086072 snoRNA:Or-CD11a - http://flybase.org/reports/FBgn0086072 snoRNA_gene - - - "snoRNA:Or-CD11a, Or-cd11a, DmOr_cd11a, CR34701" - CR34701 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267070 CR45514 - http://flybase.org/reports/FBgn0267070 non_protein_coding_gene - - - CR45514 - CR45514 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005113 l(1)184 lethal (1) 184 http://flybase.org/reports/FBgn0005113 - gene - - - l(1)184 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal eye FBgn0050298 tRNA:Thr-AGT-2-1 transfer RNA:Threonine-AGT 2-1 http://flybase.org/reports/FBgn0050298 tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "CR30298, AE002787.trna28-ThrAGT, tRNA[Thr][[3]], tRNA:thr3:47F, tRNA:T3:47F, tRNA:T:AGT:AE002787-b, tRNA[[Thr]], chr2R.trna87-ThrAGT, tRNA-Thr-AGT-2-1, tRNA:Thr-AGT-2-1, tRNA:CR30298, ACU" - CR30298 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026560 CD98 CD98 http://flybase.org/reports/FBgn0026560 - gene - - - CD98 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082193 arm::pan arm::pan http://flybase.org/reports/FBgn0082193 engineered_fusion_gene - - - arm::pan - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/first instar larval cuticle,denticle,ectopic" FBgn0014320 l(3)ry146 lethal (3) ry146 http://flybase.org/reports/FBgn0014320 - gene - - - l(3)ry146 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0067653 sd-2 sd-2 http://flybase.org/reports/FBgn0067653 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective" "photoreceptor cell & axon | somatic clone,medulla,somatic clone,lamina" FBgn0000470 dlv deltoid veins http://flybase.org/reports/FBgn0000470 - gene - - - dlv - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,body color defective" "wing,wing vein,eye,adult thorax,adult abdomen" FBgn0043028 l(2)42Eb lethal (2) 42Eb http://flybase.org/reports/FBgn0043028 gene - - - l(2)42Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0028336 l(1)G0255 lethal (1) G0255 http://flybase.org/reports/FBgn0028336 protein_coding_gene fumarate hydratase activity ; GO:0004333 | inferred from sequence or structural similarity with UniProtKB:P07954 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P07954 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 fumarate metabolic process ; GO:0006106 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle enzyme complex ; GO:0045239 | inferred from electronic annotation with InterPro:IPR005677 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P07954 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P07954 mitochondrion ; GO:0005739 | inferred from direct assay "CG4094, FBgn0029889, l(1)G0290, l(1)G0255, CG 4094" "IPR000362:Fumarate lyase family, IPR005677:Fumarate hydratase, class II, IPR008948:L-Aspartase-like, IPR018951:Fumarase C, C-terminal, IPR024083:Fumarase/histidase, N-terminal, IPR020557:Fumarate lyase, conserved site, IPR022761:Fumarate lyase, N-terminal" CG4094 11-Aug-17 DroID_v2017_08 "Drer\fh, Drer\LOC100535417" Scer\FUM1 Cele\fum-1 Xtro\fh Mmus\Fh1 Hsap\FH "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,visible" trichogen cell FBgn0039153 GatB "Glutamyl-tRNA amidotransferase, subunit B" http://flybase.org/reports/FBgn0039153 protein_coding_gene glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity ; GO:0050567 | inferred from biological aspect of ancestor with PANTHER:PTN000183793 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity ; GO:0050567 | inferred from sequence or structural similarity with UniProtKB:O75879 mitochondrial translation ; GO:0032543 | inferred from biological aspect of ancestor with PANTHER:PTN000183793 glutaminyl-tRNA aminoacylation ; GO:0006425 | inferred from sequence or structural similarity with UniProtKB:O75879 glutaminyl-tRNAGln biosynthesis via transamidation ; GO:0070681 | inferred from biological aspect of ancestor with PANTHER:PTN000183793 glutamyl-tRNA(Gln) amidotransferase complex ; GO:0030956 | inferred from biological aspect of ancestor with PANTHER:PTN000183795 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O75879 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000183795 "CG5463, GatB" "IPR003789:Aspartyl/glutamyl-tRNA amidotransferase subunit B-related, IPR004413:Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit, IPR006075:Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic, IPR017959:Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E, IPR018027:Asn/Gln amidotransferase, IPR023168:Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal" CG5463 11-Aug-17 DroID_v2017_08 "Drer\dctpp1, Drer\gatb" Scer\PET112 Cele\C39B5.6 Xtro\gatb Mmus\Gatb Hsap\GATB "partially lethal - majority die,visible" trichogen cell FBgn0053172 CG33172 - http://flybase.org/reports/FBgn0053172 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:12758 negative regulation of cell proliferation ; GO:0008285 | inferred from sequence or structural similarity with HGNC:12758 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:12758 "CG8473, CG33172" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like" CG33172 11-Aug-17 DroID_v2017_08 Drer\wdr6 Scer\RTT10 Cele\Y54E5B.2 Xtro\wdr6 Mmus\Wdr6 Hsap\WDR6 viable FBgn0010659 l(2)10425 lethal (2) 10425 http://flybase.org/reports/FBgn0010659 - gene - - - l(2)10425 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0022156 l(2)k05812 lethal (2) k05812 http://flybase.net/reports/FBgn0022156.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0264817 pre-lola-G pre-lola-G http://flybase.org/reports/FBgn0264817 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-lola-G, CG44025" IPR013087:Zinc finger C2H2-type CG44025 11-Aug-17 DroID_v2017_08 - - "Cele\sdz-28, Cele\btb-13" - - - FBgn0028280 l(1)G0417 lethal (1) G0417 http://flybase.org/reports/FBgn0028280 gene - - - l(1)G0417 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0044035 Mod(rst)D264 Mod(rst)D264 http://flybase.org/reports/FBgn0044035 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D264, Mod(rst)D264" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable eye FBgn0267424 CR45777 - http://flybase.org/reports/FBgn0267424 pseudogene_attribute - - - "CR45777, Mst77Y" - CR45777 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031688 Cyp28d2 Cyp28d2 http://flybase.org/reports/FBgn0031688 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972" - "28d2, CG6081, Cyp28d2" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV, IPR017972:Cytochrome P450, conserved site" CG6081 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp3c4, Drer\cyp3c2, Drer\cyp3c1, Drer\cyp3c3, Drer\tbxas1" "Scer\DIT2, Scer\ERG11" "Cele\cyp-13A4, Cele\cyp-13A1, Cele\cyp-43A1, Cele\cyp-25A1, Cele\cyp-13B1, Cele\cyp-13A3, Cele\cyp-33C3, Cele\cyp-25A2, Cele\cyp-25A6, Cele\cyp-13A12, Cele\cyp-13B2, Cele\cyp-13A6, Cele\cyp-13A8, Cele\cyp-13A10, Cele\cyp-13A11, Cele\cyp-13A5, Cele\cyp-25A4, Cele\cyp-25A3, Cele\cyp-13A7, Cele\cyp-13A2, Cele\cyp-44A1, Cele\cyp-33E2" "Xtro\cyp3a4, Xtro\tbxas1, Xtro\cyp3a5, Xtro\LOC100494419" "Mmus\Cyp7a1, Mmus\Cyp3a13, Mmus\Cyp3a11, Mmus\Cyp3a25, Mmus\Cyp3a57, Mmus\Cyp3a16, Mmus\Cyp3a41b, Mmus\Tbxas1, Mmus\Cyp3a44, Mmus\Cyp3a59, Mmus\Cyp3a41a" "Hsap\CYP3A7, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A4, Hsap\CYP3A5, Hsap\CYP7A1, Hsap\CYP3A43, Hsap\TBXAS1" viable FBgn0065559 l(2)SH0997 lethal (2) SH0997 http://flybase.org/reports/FBgn0065559 gene - - - "l(2)SH0997, l(2)SH2 0997" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0066364 fey forever young http://flybase.org/reports/FBgn0066364 gene - - - fey - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,recessive,lethal" FBgn0000628 eym eye missing http://flybase.org/reports/FBgn0000628 - gene - - - eym - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,fertile,partially lethal - majority die,some die during pupal stage" eye FBgn0264343 CG43799 - http://flybase.org/reports/FBgn0264343 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43799 - CG43799 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036878 Cpr76Ba Cuticular protein 76Ba http://flybase.org/reports/FBgn0036878 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr76Ba, CG9283, DmelCpr76Ba" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG9283 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable DRSC27858 K -0.065101407 -0.495237729 -0.032128727 0.483682273 4.070953529 1.864960554 FBgn0262763 Mst77Y-14Psi Male-specific pseudogene 77Y 14 http://flybase.org/reports/FBgn0262763 pseudogene_attribute - - - Mst77Y-14Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265938 CR44725 - http://flybase.org/reports/FBgn0265938 non_protein_coding_gene - - - CR44725 - CR44725 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060799 l(3)S057401 lethal (3) S057401 http://flybase.org/reports/FBgn0060799 gene - - - "0574/01, l(3)S057401" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0005049 extended extended http://flybase.org/reports/FBgn0005049 - gene - - - "ext, extended" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile" wing FBgn0004495 exb extreme bar http://flybase.org/reports/FBgn0004495 - gene - - - exb - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,ocellus" FBgn0033033 scaf scarface http://flybase.org/reports/FBgn0033033 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay "scarface, CG11066, CG15900, SPH142, scaf, scarf" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG11066 11-Aug-17 DroID_v2017_08 Drer\f9a - - - - - "viable,partially lethal - majority die,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "adult head,embryonic/first instar larval cuticle" FBgn0021746 Bm Bumpy http://flybase.org/reports/FBgn0021746 - gene - - - Bm - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,dominant" "ommatidium,eye" FBgn0060819 l(3)S052401b lethal (3) S052401b http://flybase.org/reports/FBgn0060819 gene - - - "0524/01, l(3)S052401b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265523 Smr Smrter http://flybase.org/reports/FBgn0265523 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P54253 transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN000360523 transcription corepressor activity ; GO:0003714 | traceable author statement chromatin binding ; GO:0003682 | inferred from direct assay ligand-dependent nuclear receptor binding ; GO:0016922 | inferred from biological aspect of ancestor with PANTHER:PTN000360523 "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000360523 phagocytosis ; GO:0006909 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype" transcriptional repressor complex ; GO:0017053 | inferred from physical interaction with ebi polytene chromosome ; GO:0005700 | inferred from direct assay histone deacetylase complex ; GO:0000118 | inferred from biological aspect of ancestor with PANTHER:PTN000360523 nucleoplasm ; GO:0005654 | inferred from direct assay polytene chromosome ; GO:0005700 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay "CG4013, Smr, smr, SMRTER, SMR, E52, l(1)G0361, anon-WO0153538.73, CG12719, l(1)G0060, lincRNA.983" "IPR009057:Homeobox domain-like, IPR001005:SANT/Myb domain, IPR017884:SANT domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG4013 11-Aug-17 DroID_v2017_08 "Drer\ncor2, Drer\ncor1" Scer\SNT1 Cele\gei-8 "Xtro\ncor1, Xtro\ncor2" "Mmus\Ncor1, Mmus\Spen, Mmus\Ncor2" "Hsap\PRRC2C, Hsap\NCOR2, Hsap\NCOR1" DRSC22986 K 2.858334109 0.224767518 FBgn0264477 CG43885 - http://flybase.org/reports/FBgn0264477 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43885 - CG43885 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260358 GSd238 - http://flybase.org/reports/FBgn0260358 gene - - - GSd238 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069944 CG41096 - http://flybase.org/reports/FBgn0069944 protein_coding_gene - - - CG41096 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003318 soft-brown soft brown http://flybase.org/reports/FBgn0003318 - gene - - - "soft-brown, sb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" pigment cell FBgn0035853 UbcE2M Ubiquitin conjugating enzyme E2M http://flybase.org/reports/FBgn0035853 protein_coding_gene ribosomal S6-glutamic acid ligase activity ; GO:0018169 | inferred from sequence or structural similarity with UniProtKB:P61081 NEDD8 transferase activity ; GO:0019788 | inferred from direct assay NEDD8 transferase activity ; GO:0019788 | inferred from sequence or structural similarity with UniProtKB:Q9XVK5 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with UniProtKB:P61081 cellular protein modification process ; GO:0006464 | inferred from sequence or structural similarity with UniProtKB:P61081 negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype protein neddylation ; GO:0045116 | inferred from sequence or structural similarity with UniProtKB:Q9XVK5 protein neddylation ; GO:0045116 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "CG7375, anon-WO0118547.309, Ubc12, dUbc12, UbcD12, UbcE2M, ubcD12" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG7375 11-Aug-17 DroID_v2017_08 "Drer\ube2f, Drer\si:ch1073-205c8.3" Scer\UBC12 Cele\ubc-12 "Xtro\ube2m, Xtro\ube2f" "Mmus\Ube2m, Mmus\Ube2f" "Hsap\UBE2F, Hsap\UBE2M" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC10828 E 0.468169387 0.234486297 2.395199241 1.465022276 1.067751269 -0.147040037 FBgn0033388 CG8046 - http://flybase.org/reports/FBgn0033388 protein_coding_gene glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from electronic annotation with InterPro:IPR000447 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000447 glycerol-3-phosphate metabolic process ; GO:0006072 | inferred from electronic annotation with InterPro:IPR000447 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR000447 CG8046 "IPR000447:FAD-dependent glycerol-3-phosphate dehydrogenase, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8046 11-Aug-17 DroID_v2017_08 "Drer\slc46a3, Drer\si:dkey-5g14.1, Drer\hiat1a, Drer\si:ch211-262i1.4, Drer\LOC557306, Drer\zgc:174356, Drer\hiat1b, Drer\LOC100002406, Drer\slc46a1" Scer\YJL163C "Cele\F40F9.5, Cele\Y43F8A.5, Cele\Y4C6B.5, Cele\C46C11.2" "Xtro\mfsd14b, Xtro\mfsd14a, Xtro\slc46a1, Xtro\slc46a2" "Mmus\Slc46a1, Mmus\Slc46a2, Mmus\Mfsd14a, Mmus\Slc46a3, Mmus\Mfsd14b" "Hsap\MFSD14A, Hsap\SLC46A1, Hsap\SLC46A2, Hsap\SLC46A3, Hsap\MFSD14B" viable FBgn0024271 ZAM\gag ZAM element gag http://flybase.org/reports/FBgn0024271 - transposable_element_gene - - - "ORF1, ZAM\gag, gag, ZAM gag" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262146 MtnE Metallothionein E http://flybase.org/reports/FBgn0262146 protein_coding_gene metal ion binding ; GO:0046872 | inferred from direct assay response to copper ion ; GO:0046688 | inferred from direct assay detoxification of cadmium ion ; GO:0071585 | inferred from direct assay response to silver ion ; GO:0010272 | inferred from direct assay response to mercury ion ; GO:0046689 | inferred from direct assay response to zinc ion ; GO:0010043 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "MtnE, CG42872, DMG8-chr3R.29.007" "IPR000966:Metallothionein, family 5, Diptera" CG42872 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061506 l(2)24Ad lethal (2) 24Ad http://flybase.org/reports/FBgn0061506 gene - - - l(2)24Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0061487 plpg polyplegic http://flybase.org/reports/FBgn0061487 gene - - - plpg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0060309 l(3)S148016 lethal (3) S148016 http://flybase.org/reports/FBgn0060309 gene - - - "1480/16, l(3)S148016" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053287 CG33287 - http://flybase.org/reports/FBgn0053287 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12982, CG33287" "IPR022110:Casc1 domain, IPR031826:Cancer susceptibility candidate 1, N-terminal" CG33287 11-Aug-17 DroID_v2017_08 Drer\casc1 - Cele\K09E2.2 - Mmus\Casc1 Hsap\CASC1 "viable,fertile" FBgn0005731 l(1)TK207 lethal (1) TK207 http://flybase.org/reports/FBgn0005731 - gene - - - "l207, l(1)TK207" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0034460 CG18367 - http://flybase.org/reports/FBgn0034460 protein_coding_gene - - - "CG15123, CG18367" IPR032135:Protein of unknown function DUF4817 CG18367 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030571 CG14414 - http://flybase.org/reports/FBgn0030571 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg14414, BcDNA:AT01764, CG14414" IPR000504:RNA recognition motif domain CG14414 11-Aug-17 DroID_v2017_08 Drer\rbm18 - - Xtro\rbm18 Mmus\Rbm18 Hsap\RBM18 "viable,fertile,visible" trichogen cell FBgn0019692 l(3)68Fi lethal (3) 68Fi http://flybase.org/reports/FBgn0019692 - gene - - - "l(3)68Fe, l(3)68Fi" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0263327 CR43408 - http://flybase.org/reports/FBgn0263327 non_protein_coding_gene - - - "CG43408, CR43408" - CR43408 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085525 CG40849 - http://flybase.org/reports/FBgn0085525 protein_coding_gene - - - CG40849 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266948 CR45399 - http://flybase.org/reports/FBgn0266948 non_protein_coding_gene - - - CR45399 - CR45399 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262431 mir-1003 mir-1003 stem loop http://flybase.org/reports/FBgn0262431 miRNA_gene - miRNA mediated inhibition of translation ; GO:0035278 | inferred from direct assay - "mir-1003, miR-1003, dme-mir-1003, 1003, CR42987, dme-miR-1003" - CR42987 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,lethal" "wing,wing vein" FBgn0053424 5SrRNA:CR33424 5SrRNA:CR33424 http://flybase.org/reports/FBgn0053424 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33424, 5SrRNA:CR33424" - CR33424 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0082366 EP3645 EP3645 http://flybase.org/reports/FBgn0082366 gene - - - EP3645 - - 11-Aug-17 DroID_v2017_08 - - - - - - increased cell death spermatogonium FBgn0022360 Scbp Soluble calcium-binding protein http://flybase.org/reports/FBgn0022360 - gene calcium ion binding ; GO:0005509 | inferred from direct assay - - "SCBP, Scbp" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000690 flrdN flight reduced N http://flybase.org/reports/FBgn0000690 - gene - - - flrdN - - 11-Aug-17 DroID_v2017_08 - - - - - - "jumping defective,flightless,heat sensitive,flight defective" FBgn0031312 Tango14 Transport and Golgi organization 14 http://flybase.org/reports/FBgn0031312 protein_coding_gene "transferase activity, transferring alkyl or aryl (other than methyl) groups ; GO:0016765 | inferred from electronic annotation with InterPro:IPR001441" wing disc development ; GO:0035220 | inferred from genetic interaction with Bx protein secretion ; GO:0009306 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG4775, TANGO14, l(2)k00619, BcDNA:SD10843, Tango14, Tango 14" IPR001441:Decaprenyl diphosphate synthase-like CG4775 11-Aug-17 DroID_v2017_08 Drer\nus1 Scer\NUS1 Cele\F37B12.3 Xtro\nus1 Mmus\Nus1 Hsap\NUS1 "lethal,recessive" FBgn0052333 CG32333 - http://flybase.org/reports/FBgn0052333 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000280657 cellular lipid metabolic process ; GO:0044255 | inferred from biological aspect of ancestor with PANTHER:PTN000280657 - "CG9146, CG9137, CG32333, cg32333" "IPR029058:Alpha/Beta hydrolase fold, IPR022122:Protein FAM135, IPR007751:Domain of unknown function DUF676, lipase-like" CG32333 11-Aug-17 DroID_v2017_08 "Drer\fam135b, Drer\fam135a" Scer\LPL1 Cele\C09D4.4 Xtro\fam135a "Mmus\Fam135b, Mmus\Fam135a" "Hsap\FAM135A, Hsap\FAM135B" "viable,fertile,visible" "antenna,leg,ectopic" FBgn0042166 CG18846 - http://flybase.org/reports/FBgn0042166 protein_coding_gene - - - CG18846 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261067 LSm1 Like Sm 1 http://flybase.org/reports/FBgn0261067 protein_coding_gene RNA cap binding ; GO:0000339 | inferred from biological aspect of ancestor with PANTHER:PTN000400406 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with protein_id:CAB45865 cytoplasmic mRNA processing body assembly ; GO:0033962 | inferred from mutant phenotype RNA processing ; GO:0006396 | inferred from sequence or structural similarity with SGD:S000003660 deadenylation-dependent decapping of nuclear-transcribed mRNA ; GO:0000290 | inferred from biological aspect of ancestor with PANTHER:PTN000400406" cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000400406 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000400405 "CG4279, LSm1, Lsm1" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR034104:Sm-like protein Lsm1" CG4279 11-Aug-17 DroID_v2017_08 Drer\lsm1 Scer\LSM1 Cele\lsm-1 Xtro\lsm1 Mmus\Lsm1 Hsap\LSM1 FBgn0266763 CR45228 - http://flybase.org/reports/FBgn0266763 non_protein_coding_gene - - - CR45228 - CR45228 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035623 mthl2 methuselah-like 2 http://flybase.org/reports/FBgn0035623 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "Mth-2, CG17795, anon-WO0170980.29, anon-WO0170980.28, mthl2" "IPR017981:GPCR, family 2-like, IPR000832:GPCR, family 2, secretin-like, IPR010596:Methuselah, N-terminal domain, IPR017452:GPCR, rhodopsin-like, 7TM, IPR023311:Methuselah ectodomain, domain 2" CG17795 11-Aug-17 DroID_v2017_08 "Drer\adgrl2a, Drer\fbn2b, Drer\LOC101886975, Drer\adgrf11, Drer\adgre14, Drer\adgrd2, Drer\adgrf6, Drer\adgrg4a, Drer\LOC100537181, Drer\fbn2a, Drer\adgrg11, Drer\LOC100535070, Drer\LOC100538279, Drer\adgrg6, Drer\adgre5b.3, Drer\adgrl4, Drer\adgrf3a, Drer\adgrg3, Drer\adgrl1a, Drer\adgrl3.1, Drer\adgrg2a, Drer\LOC101884341, Drer\adgre10, Drer\adgrg1" - Cele\lat-2 "Xtro\adgrv1, Xtro\adgrd1, Xtro\adgrl1, Xtro\adgrg1, Xtro\gpr157, Xtro\adgrf1, Xtro\adgrf3, Xtro\adgre5" "Mmus\Adgre4, Mmus\Adgrf1, Mmus\Adgre1, Mmus\Adgrg5, Mmus\Adgrg2, Mmus\Adgrd1, Mmus\Adgre5, Mmus\Adgrg1, Mmus\Adgrl2, Mmus\Adgrg4, Mmus\Adgrl4, Mmus\Adgrf3, Mmus\Adgrg3, Mmus\Adgrf4, Mmus\Adgrf5, Mmus\Adgrg6, Mmus\Adgrg7, Mmus\Adgrf2, Mmus\Adgrl3, Mmus\Adgrl1" "Hsap\FBN3, Hsap\ADGRG2, Hsap\ADGRG3, Hsap\ADGRE5, Hsap\ADGRG5, Hsap\ADGRG6, Hsap\ADGRE2, Hsap\ADGRF1, Hsap\ADGRG4, Hsap\ADGRG1, Hsap\ADGRF3, Hsap\ADGRL4, Hsap\ADGRE1, Hsap\ADGRD2, Hsap\ADGRG7, Hsap\ADGRE3, Hsap\ADGRL1, Hsap\ADGRF4, Hsap\ADGRL2, Hsap\ADGRF5, Hsap\ADGRL3, Hsap\ADGRF2, Hsap\ADGRD1" "viable,fertile" FBgn0065164 l(3)SH035 lethal (3) SH035 http://flybase.org/reports/FBgn0065164 gene - - - "l(3)SH035, l(2)SH3 035" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026260 bundled bundled http://flybase.org/reports/FBgn0026260 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available bundled - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032369 CG6614 - http://flybase.org/reports/FBgn0032369 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG6614 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG6614 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-254e1.1, Drer\ttc34, Drer\ttc7b, Drer\ttc7a" - Cele\ttc-7 - "Mmus\Ttc34, Mmus\Ttc7b, Mmus\Cfap70, Mmus\Ttc7" "Hsap\TTC34, Hsap\TTC7B, Hsap\TTC7A, Hsap\CFAP70" viable FBgn0069104 mus320 mutagen-sensitive 320 http://flybase.org/reports/FBgn0069104 gene - - - mus320 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0045479 Gr64a Gustatory receptor 64a http://flybase.org/reports/FBgn0045479 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity taste receptor activity ; GO:0008527 | non-traceable author statement "sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity detection of sucrose stimulus ; GO:0009731 | inferred from mutant phenotype sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype detection of maltose stimulus ; GO:0034289 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from genetic interaction with Gr64f detection of glucose ; GO:0051594 | inferred from mutant phenotype sensory perception of sweet taste ; GO:0050916 | inferred from genetic interaction with Gr64d, Gr64e, Gr64c, Gr64b, Gr64f proboscis extension reflex ; GO:0007637 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | non-traceable author statement" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009318 integral component of membrane ; GO:0016021 | non-traceable author statement "GrLU3, Gr64A1, CG14986, LU.3, GRLU.3, CG32261, Gr64a, Dmel64a, Gr64, GR64a" IPR009318:Gustatory receptor CG32261 11-Aug-17 DroID_v2017_08 - - - - - - "taste perception defective,neurophysiology defective,proboscis extension reflex defective,viable,fertile" large labellar taste bristle DRSC21713 IE 2.459680437 -0.244616344 1.609006979 0.421405181 0.022541583 -0.355117504 FBgn0039956 CG17418 - http://flybase.org/reports/FBgn0039956 protein_coding_gene - - - CG17418 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0035007 CG3492 - http://flybase.org/reports/FBgn0035007 protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 - "anon-WO0140519.253, CG3492" "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain" CG3492 11-Aug-17 DroID_v2017_08 "Drer\ppifb, Drer\ppiab, Drer\ppiaa, Drer\ppifa, Drer\ppil6, Drer\ppwd1" "Scer\CPR3, Scer\CPR1" Cele\cyn-15 "Xtro\ppia, Xtro\ppif" "Mmus\Ppif, Mmus\Ppil6, Mmus\Ranbp2, Mmus\Ppia, Mmus\Ppwd1" "Hsap\PPIL6, Hsap\LOC105371242, Hsap\PPIAL4G, Hsap\PPIAL4D, Hsap\RANBP2, Hsap\PPIAL4E, Hsap\PPIA, Hsap\PPWD1, Hsap\PPIAL4C, Hsap\PPIAL4A, Hsap\PPIF" viable FBgn0034322 CG18536 - http://flybase.org/reports/FBgn0034322 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18536 IPR010512:Protein of unknown function DUF1091 CG18536 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0260469 CR14578 - http://flybase.org/reports/FBgn0260469 pseudogene_attribute - - - "CG40105, CR14578, CG14578" - CR14578 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264810 Pburs Partner of Bursicon http://flybase.org/reports/FBgn0264810 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | contributes_to inferred by curator from GO:0031395 G-protein coupled receptor binding ; GO:0001664 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:Q9VD83 neuropeptide receptor binding ; GO:0071855 | contributes_to inferred from physical interaction with rk neuropeptide hormone activity ; GO:0005184 | contributes_to inferred from direct assay "chitin-based cuticle sclerotization ; GO:0007593 | inferred from mutant phenotype regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from direct assay bursicon neuropeptide hormone complex ; GO:0031395 | inferred from physical interaction with Burs bursicon neuropeptide hormone complex ; GO:0031395 | inferred from direct assay "pburs, bursbeta, CG15284, pu, pup, pads-b, A, Bursbeta, burs-beta, burs beta, Burs beta, PBURS, Bur beta, Pburs" "IPR034441:Bursicon subunit beta, IPR029034:Cystine-knot cytokine" CG15284 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005296 mei-2606 meiotic 2606 http://flybase.org/reports/FBgn0005296 - gene - - - "2606, mei-2696, mei-2606" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0032768 CG17564 - http://flybase.org/reports/FBgn0032768 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17564 IPR025252:Domain of unknown function DUF4200 CG17564 11-Aug-17 DroID_v2017_08 Drer\cfap73 - - Xtro\cfap73 "Mmus\Ccdc42, Mmus\Cfap73" "Hsap\CFAP73, Hsap\CCDC42" viable FBgn0060747 l(3)S065303 lethal (3) S065303 http://flybase.org/reports/FBgn0060747 gene - - - "0653/03, l(3)S065303" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0243586 Tb Tubby http://flybase.org/reports/FBgn0243586 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "Tb, TwdlA, CG5480, Tu" "IPR004145:Domain of unknown function DUF243, IPR007085:DNA/pantothenate metabolism flavoprotein, C-terminal" CG5480 11-Aug-17 DroID_v2017_08 - - - - - - DRSC15815 K 0.312675537 -0.15122553 0.12419505 -0.311329107 1.526959221 0.787314656 FBgn0065457 l(2)SH1385 lethal (2) SH1385 http://flybase.org/reports/FBgn0065457 gene - - - "l(2)SH1385, l(2)SH2 1385" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039272 CG11836 - http://flybase.org/reports/FBgn0039272 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP23, CG11836" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11836 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-238d18.3, Drer\zgc:171592, Drer\zgc:154142, Drer\zgc:92511, Drer\tmprss4a, Drer\zgc:112302, Drer\ctrl, Drer\zgc:112368, Drer\tmprss4b, Drer\f10, Drer\si:dkey-57c15.4, Drer\ela2, Drer\zgc:92745, Drer\zgc:92041, Drer\ctrb1, Drer\tmprss13a, Drer\si:dkey-33i11.3, Drer\masp2, Drer\tmprss3a, Drer\ela2l, Drer\zgc:112285, Drer\zgc:112160, Drer\LOC562139, Drer\ela3l" - "Cele\try-1, Cele\try-3, Cele\svh-1" "Xtro\cela2a, Xtro\cela3a, Xtro\f10, Xtro\LOC100135144, Xtro\f9, Xtro\ctrb1, Xtro\ctrb2" "Mmus\Tmprss11e, Mmus\F10, Mmus\Proz, Mmus\Ctrl, Mmus\Cela3b, Mmus\Cela2a, Mmus\Cfd, Mmus\Tmprss11d, Mmus\Tmprss11a, Mmus\Ctrb1, Mmus\Cela3a, Mmus\Tmprss11f, Mmus\Tmprss11g, Mmus\Tmprss11b, Mmus\Tmprss11c, Mmus\Ctrc, Mmus\Cela1" "Hsap\TMPRSS3, Hsap\TMPRSS5, Hsap\CELA1, Hsap\CELA3B, Hsap\CELA2A, Hsap\OVCH1, Hsap\CTRB1, Hsap\CFD, Hsap\MASP2, Hsap\F10, Hsap\HPN, Hsap\CTRL, Hsap\CTRC, Hsap\CTRB2, Hsap\CELA3A, Hsap\TMPRSS2, Hsap\PROZ, Hsap\CELA2B" "lethal,recessive,viable" FBgn0013619 l(3)W33B lethal (3) W33B http://flybase.org/reports/FBgn0013619 - gene - - - l(3)W33B - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0037206 CG12768 - http://flybase.org/reports/FBgn0037206 protein_coding_gene - - - CG12768 IPR006578:MADF domain CG12768 11-Aug-17 DroID_v2017_08 "Drer\LOC100330838, Drer\si:ch211-207i20.3, Drer\zgc:152938" - "Cele\madf-2, Cele\madf-9, Cele\madf-8, Cele\madf-10, Cele\madf-5, Cele\madf-4, Cele\madf-3" - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265977 CR44756 - http://flybase.org/reports/FBgn0265977 non_protein_coding_gene - - - CR44756 - CR44756 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001631 l(1)dn8 lethal (1) discs normal 8 http://flybase.org/reports/FBgn0001631 - gene - - - "l(1)d.norm.-8, l(1)dn8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037207 Mes2 Mesoderm-expressed 2 http://flybase.org/reports/FBgn0037207 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "instar larval development ; GO:0002168 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "adfR, CG11100, Mes2, mes2, MES2" IPR006578:MADF domain CG11100 11-Aug-17 DroID_v2017_08 "Drer\LOC100330838, Drer\zgc:152938, Drer\si:ch211-207i20.3" - "Cele\madf-9, Cele\madf-5, Cele\madf-3, Cele\madf-8, Cele\madf-4, Cele\madf-10, Cele\madf-2" - - - embryonic stage | cellular blastoderm mesoderm anlage

"lethal,hypoactive,body size defective,germline clone,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of larval stage,some die during larval stage" "embryonic/first instar larval cuticle,germline clone,embryonic dorsal epidermis | dorsal closure stage,embryonic leading edge cell,embryonic epidermis,wing,haltere" DRSC11632 IEK -0.095494179 -1.597528568 -3.332453545 -0.469981367 1.194888558 5.160337761 FBgn0062608 Mod(var)1328 Mod(var)1328 http://flybase.org/reports/FBgn0062608 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1328, Mod(var)1328" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0065432 l(2)SH1489 lethal (2) SH1489 http://flybase.org/reports/FBgn0065432 gene - - - l(2)SH1489 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0051054 CR31054 - http://flybase.org/reports/FBgn0051054 pseudogene_attribute - - - "CG31054, CR31054" - CR31054 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22134 E 0.535374978 0.875818253 2.354701031 1.503626397 -0.033511893 -0.329952562 FBgn0031636 CG12194 - http://flybase.org/reports/FBgn0031636 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "anon-EST:Posey105, CG12194" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG12194 11-Aug-17 DroID_v2017_08 "Drer\im:7160594, Drer\mfsd1" - - "Xtro\mfsd1, Xtro\LOC100487982" Mmus\Mfsd1 Hsap\MFSD1 viable FBgn0266430 CG45060 - http://flybase.org/reports/FBgn0266430 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45060, CG42262, CG15245, CG32696, CG15246" - CG45060 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267862 CR46150 - http://flybase.org/reports/FBgn0267862 pseudogene_attribute - - - "CR46150, CG12717-related" - CR46150 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031273 CG2839 - http://flybase.org/reports/FBgn0031273 protein_coding_gene - - - CG2839 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG2839 11-Aug-17 DroID_v2017_08 "Drer\zgc:174904, Drer\hbl4, Drer\clec11a, Drer\illr2, Drer\si:ch73-86n18.1, Drer\hbl2, Drer\hbl1, Drer\hbl3, Drer\colec11, Drer\si:ch211-116m6.3" - "Cele\clec-145, Cele\clec-78, Cele\clec-149, Cele\F49E2.5, Cele\ajm-1, Cele\H39E23.3, Cele\clec-178, Cele\F07F6.2" "Xtro\colec10, Xtro\colec11, Xtro\clec3b" "Mmus\Tchh, Mmus\Sftpd, Mmus\Nefh, Mmus\Clec4e, Mmus\Sftpa1, Mmus\Cd209c, Mmus\Klra17, Mmus\Mbl2, Mmus\Mbl1, Mmus\Clec1a, Mmus\Colec11, Mmus\Klra2, Mmus\Clec1b, Mmus\Colec10" "Hsap\COLEC10, Hsap\CLEC1B, Hsap\CLEC10A, Hsap\SFTPD, Hsap\COLEC11, Hsap\SFTPA1, Hsap\NEFH, Hsap\TCHH, Hsap\CLEC11A, Hsap\CLEC12B, Hsap\CLEC3A, Hsap\CD72, Hsap\SFTPA2, Hsap\MBL2, Hsap\TRDN, Hsap\CLEC4A" "partially lethal - majority die,some die during pupal stage" DRSC00544 K -0.8759697 0.366147364 -0.375135352 0.837865786 -0.097954025 -1.552084745 FBgn0259651 B0326 - http://flybase.org/reports/FBgn0259651 gene - - - B0326 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing sensillum,ectopic,chaeta,wing,distal" FBgn0025756 l(3)93DFf lethal (3) 93DFf http://flybase.org/reports/FBgn0025756 - gene - - - l(3)93DFf - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0064168 l(3)68.43 lethal (3) 68.43 http://flybase.org/reports/FBgn0064168 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "68.43, l(3)68.43" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal "nurse cell ring canal,germline clone" FBgn0037772 Spn85F Serpin 85F http://flybase.org/reports/FBgn0037772 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues - extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "Spn85F, CG12807" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG12807 11-Aug-17 DroID_v2017_08 "Drer\serpinb1, Drer\serpina10a, Drer\si:ch1073-416d2.3, Drer\serpinb1l3, Drer\serpinc1, Drer\serpinb1l2, Drer\serpinb1l1, Drer\serpine2, Drer\zgc:173729, Drer\serpine1, Drer\serpinb1l4, Drer\serpine3, Drer\serpinh1b, Drer\serpinh2, Drer\serpinh1a" - Cele\srp-1 - "Mmus\Serpinh1, Mmus\Serpinb6c, Mmus\Serpinb9, Mmus\Serpinb1b, Mmus\Serping1, Mmus\Serpinb12, Mmus\Serpinb2, Mmus\Serpinb3c, Mmus\Serpinb1a, Mmus\Serpine2, Mmus\Serpinb9c, Mmus\Serpinb3d, Mmus\Serpinb6d, Mmus\Serpine1, Mmus\Serpinb10, Mmus\Serpinb9d, Mmus\Serpinb11, Mmus\Serpinb8, Mmus\Serpinb13, Mmus\Serpinb5, Mmus\Serpinb1c, Mmus\Serpinb3b, Mmus\Serpinb3a, Mmus\Serpinb9g, Mmus\Serpinb9f, Mmus\Serpine3, Mmus\Serpinc1, Mmus\Serpinb6a, Mmus\Serpina10, Mmus\Serpinb6b, Mmus\Gm11397, Mmus\Serpinb9b, Mmus\Serpinb9e, Mmus\Serpinb6e" "Hsap\SERPINE1, Hsap\SERPINB9, Hsap\SERPINB8, Hsap\SERPINB2, Hsap\SERPINH1, Hsap\SERPINB13, Hsap\SERPINC1, Hsap\SERPINB1, Hsap\SERPINB4, Hsap\SERPINB11, Hsap\SERPINE3, Hsap\SERPINA10, Hsap\HMSD, Hsap\SERPING1, Hsap\SERPINE2, Hsap\SERPINB10, Hsap\SERPINB3, Hsap\SERPINB6, Hsap\SERPINB5, Hsap\SERPINB12" FBgn0037998 CG4848 - http://flybase.org/reports/FBgn0037998 protein_coding_gene molecular_function ; GO:0003674 | no biological data available Golgi organization ; GO:0007030 | inferred from sequence or structural similarity with SGD:S000003191 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000003191 Golgi transport complex ; GO:0017119 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:6545 "CG4848, Cog1" IPR033370:Conserved oligomeric Golgi complex subunit 1 CG4848 11-Aug-17 DroID_v2017_08 Drer\cog1 - Cele\cogc-1 Xtro\cog1 Mmus\Cog1 Hsap\COG1 viable FBgn0021923 l(2)k11226 lethal (2) k11226 http://flybase.org/reports/FBgn0021923 - gene - - - l(2)k11226 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0065294 l(2)SH2002 lethal (2) SH2002 http://flybase.org/reports/FBgn0065294 gene - - - "l(2)SH2002, l(2)SH2 2002" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263706 CG43658 - http://flybase.org/reports/FBgn0263706 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with HGNC:14103 regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 positive regulation of Rho protein signal transduction ; GO:0035025 | inferred by curator from GO:0005089 imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG43658, CG8557, CG12432" "IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR011993:PH domain-like, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain" CG43658 11-Aug-17 DroID_v2017_08 "Drer\arhgef10, Drer\arhgef10lb, Drer\arhgef10la" - Cele\osg-1 "Xtro\kdm7a, Xtro\LOC100493255, Xtro\arhgef10l" "Mmus\Arhgef10, Mmus\Arhgef17, Mmus\Arhgef10l" "Hsap\ARHGEF10, Hsap\ARHGEF17, Hsap\ARHGEF10L" FBgn0261113 Xrp1 Xrp1 http://flybase.org/reports/FBgn0261113 protein_coding_gene P-element binding ; GO:0003693 | inferred from direct assay protein dimerization activity ; GO:0046983 | inferred from sequence or structural similarity double-strand break repair ; GO:0006302 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from direct assay cellular process ; GO:0009987 | inferred from mutant phenotype DNA repair complex ; GO:1990391 | inferred from direct assay "Xrp1, clone 2.44, anon-EST:Liang-2.44, CG17836, XRP1, 2515, l(3)02515, xrp1, DM28" - CG17836 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083081 linc lincoyan http://flybase.org/reports/FBgn0083081 gene - - - linc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026563 CG1979 - http://flybase.org/reports/FBgn0026563 FBgn0063238 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sleep ; GO:0030431 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "BcDNA:GH19145, BG:DS00464.1, CG1979" - CG1979 11-Aug-17 DroID_v2017_08 Drer\si:ch211-116m6.3 - "Cele\H39E23.3, Cele\F35A5.1" - - - viable DRSC24707 K 0.552827875 -0.045677339 -0.735371262 -0.29379157 -1.000593264 -1.635708155 FBgn0085404 CG34375 - http://flybase.org/reports/FBgn0085404 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model multicellular organism development ; GO:0007275 | inferred from electronic annotation with InterPro:IPR004162 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR004162 biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR004162 cellular_component ; GO:0005575 | no biological data available "CG34375, CG13834, CG13835" "IPR001478:PDZ domain, IPR001841:Zinc finger, RING-type, IPR004162:E3 ubiquitin-protein ligase SIN-like, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG34375 11-Aug-17 DroID_v2017_08 "Drer\siah1, Drer\il16, Drer\inadl, Drer\siah2l, Drer\pdzd7b, Drer\dlg5a, Drer\cyhr1, Drer\lnx1, Drer\slc9a3r1, Drer\pard3bb, Drer\si:dkey-92i15.4, Drer\grid2ipa, Drer\grip1, Drer\grip2b" - Cele\siah-1 "Xtro\lnx1, Xtro\grip2, Xtro\dlg5, Xtro\siah1, Xtro\grid2ip, Xtro\grip1, Xtro\siah2" "Mmus\Pdzd2, Mmus\Ush1c, Mmus\Grasp, Mmus\Lnx1, Mmus\Patj, Mmus\Pdzph1, Mmus\Cyhr1, Mmus\Grip1, Mmus\6330408A02Rik, Mmus\Siah1b, Mmus\Il16, Mmus\Siah1a, Mmus\Dlg5, Mmus\Pdzd11, Mmus\Grid2ip, Mmus\Siah3, Mmus\Grip2, Mmus\Siah2, Mmus\Mpdz" "Hsap\MPDZ, Hsap\PARD3B, Hsap\CYHR1, Hsap\GRASP, Hsap\PATJ, Hsap\SIAH2, Hsap\USH1C, Hsap\PDZD2, Hsap\FRMPD2, Hsap\DLG5, Hsap\GRID2IP, Hsap\GRIP1, Hsap\SIAH1, Hsap\SIAH3, Hsap\IL16, Hsap\C19orf68, Hsap\LNX1" viable FBgn0265736 CR44543 - http://flybase.org/reports/FBgn0265736 non_protein_coding_gene - - - CR44543 - CR44543 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025473 qkr58E-4 quaking related 58E-4 http://flybase.org/reports/FBgn0025473 - gene - - - "qrk58E-4, qkr58E-4" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016691 ATPsynO "ATP synthase, oligomycin sensitivity conferring protein" http://flybase.org/reports/FBgn0016691 - protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000002706" proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P48047 mitochondrial ATP synthesis coupled proton transport ; GO:0042776 | inferred from sequence or structural similarity with HGNC:850 "lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial proton-transporting ATP synthase, central stalk ; GO:0005756 | inferred from sequence or structural similarity with UniProtKB:P48047" "OSCP, CG4307, Oscp, ATPO_DROME, ATPO, ATPsynO, oscp" "IPR000711:ATPase, OSCP/delta subunit, IPR026015:F1F0 ATP synthase OSCP/delta subunit, N-terminal domain" CG4307 11-Aug-17 DroID_v2017_08 Drer\atp5o Scer\ATP5 Cele\atp-3 Xtro\atp5o Mmus\Atp5o Hsap\ATP5O "lethal,RU486 conditional,developmental rate defective,female sterile,short lived,male,female,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0001520 l(1)11Ad lethal (1) 11Ad http://flybase.org/reports/FBgn0001520 - gene - - - "l(1)VA213, A4, l(1)11Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010872 l(3)05652 lethal (3) 05652 http://flybase.org/reports/FBgn0010872 - gene - - - l(3)05652 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive,visible" wing FBgn0004974 NucIII Nuclease III http://flybase.org/reports/FBgn0004974 - gene deoxyribonuclease activity ; GO:0004536 | inferred from direct assay endonuclease activity ; GO:0004519 | inferred from direct assay exonuclease activity ; GO:0004527 | inferred from direct assay ribonuclease activity ; GO:0004540 | inferred from direct assay - - NucIII - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039650 Mesh1 Metazoan SpoT homolog-1 http://flybase.org/reports/FBgn0039650 protein_coding_gene "guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity ; GO:0008893 | inferred from direct assay" response to starvation ; GO:0042594 | inferred from mutant phenotype guanosine tetraphosphate catabolic process ; GO:0015971 | inferred from direct assay - "Mesh1, Q9VAM9, CG11900" IPR003607:HD/PDEase domain CG11900 11-Aug-17 DroID_v2017_08 Drer\hddc3 - Cele\ZK909.3 Xtro\hddc3 Mmus\Hddc3 Hsap\HDDC3 "viable,small body,stress response defective" FBgn0261515 CG10485 - http://flybase.org/reports/FBgn0261515 protein_coding_gene - - - CG10485 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024150 Ac78C Adenylyl cyclase 78C http://flybase.org/reports/FBgn0024150 FBgn0040639 protein_coding_gene adenylate cyclase activity ; GO:0004016 | inferred from electronic annotation with InterPro:IPR009398 guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 adenylate cyclase activity ; GO:0004016 | non-traceable author statement "cAMP biosynthetic process ; GO:0006171 | inferred from electronic annotation with InterPro:IPR009398 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 response to sucrose ; GO:0009744 | inferred from direct assay response to caffeine ; GO:0031000 | inferred from direct assay signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 detection of chemical stimulus involved in sensory perception of sweet taste ; GO:0001582 | inferred from mutant phenotype response to trehalose ; GO:0010353 | inferred from direct assay" "guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924" "CG10564, AC 78C, DAC78C, DAC78C-s, CG10554, Ac78C, AC78C" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR009398:Adenylate cyclase, conserved domain, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase, IPR032628:Adenylate cyclase, N-terminal" CG10564 11-Aug-17 DroID_v2017_08 "Drer\adcy2a, Drer\adcy1b, Drer\si:ch211-132f19.7, Drer\adcy1a, Drer\adcy6a, Drer\si:dkey-206f10.1, Drer\adcy2b, Drer\adcy5, Drer\adcy7, Drer\adcy3a, Drer\adcy8, Drer\adcy6b" - "Cele\acy-4, Cele\acy-2, Cele\acy-3" "Xtro\adcy1, Xtro\adcy8, Xtro\adcy6, Xtro\dnajc27, Xtro\adcy4, Xtro\adcy7" "Mmus\Adcy2, Mmus\Adcy1, Mmus\Adcy3, Mmus\Adcy8, Mmus\Adcy6, Mmus\Adcy4, Mmus\Adcy5, Mmus\Adcy7" "Hsap\ADCY4, Hsap\ADCY3, Hsap\ADCY8, Hsap\ADCY6, Hsap\ADCY7, Hsap\ADCY5, Hsap\ADCY1, Hsap\ADCY2" " embryonic stage | stage 7-8 , embryonic stage | >= 8 hr , embryonic stage | 2-4 hr , adult stage , embryonic stage | late , larval stage , embryonic stage | stage 4-8 " " anterior transverse furrow

,

ubiquitous , cephalic furrow

, posterior transverse furrow

" chemosensitive behavior defective FBgn0260114 2L4105 - http://flybase.org/reports/FBgn0260114 gene - - - 2L4105 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0266690 CR45180 - http://flybase.org/reports/FBgn0266690 non_protein_coding_gene - - - CR45180 - CR45180 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263944 BG00472 - http://flybase.org/reports/FBgn0263944 gene - - - BG00472 - - 11-Aug-17 DroID_v2017_08 - - - - - - "starvation stress response defective,temperature response defective,gravitaxis defective,long lived,male limited" FBgn0050077 Blos1 "Biogenesis of lysosome-related organelles complex 1, subunit 1" http://flybase.org/reports/FBgn0050077 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Pldn olfactory learning ; GO:0008355 | inferred from mutant phenotype eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from biological aspect of ancestor with PANTHER:PTN000317312 synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype BLOC-1 complex ; GO:0031083 | inferred from biological aspect of ancestor with PANTHER:PTN000317312 BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:4200 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000317312 "CG10127, CG30077, blos1, BLOS1, NP_725401, Blos1" IPR009395:Biogenesis of lysosome-related organelles complex 1 subunit 1 CG30077 11-Aug-17 DroID_v2017_08 Drer\bloc1s1 - Cele\blos-1 Xtro\bloc1s1 Mmus\Bloc1s1 Hsap\BLOC1S1 "viable,fertile,eye color defective,recessive,neurophysiology defective,courtship behavior defective,male,hyperactive" photoreceptor cell pigment granule FBgn0011975 tRNA:Ser-CGA-1-1 transfer RNA:Serine-CGA 1-1 http://flybase.org/reports/FBgn0011975 "FBgn0003826, FBgn0011968, FBgn0011973, FBgn0052621, FBgn0060063" tRNA_gene UCG codon-amino acid adaptor activity ; GO:0033408 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033408 cytosol ; GO:0005829 | inferred by curator from GO:0033408 "444-1, Ser-tRNA-4, tRNA-Ser, tRNA[Ser], Ser tRNA[Ser], AE002593.trna2-SerCGA, tRNA:S:CGA:AE002593-a, CR32621, tRNA:ser, tRNA:S, tRNA:ser4, tRNA:S4, tRNA:ser4:12Ea, tRNA[[Ser]], chrX.trna6-SerCGA, tRNA-Ser-CGA-1-1, tRNA:Ser-CGA-1-1, tRNA:S4:12Ea, UCG" - CR32621 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0069220 gl(2R)62-37 gl(2R)62-37 http://flybase.org/reports/FBgn0069220 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(2R)62-37 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,non-rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryo,germline clone,maternal effect,posterior" FBgn0053506 CG33506 - http://flybase.org/reports/FBgn0053506 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG10220, CG33506" IPR026620:Transmembrane protein 177 CG33506 11-Aug-17 DroID_v2017_08 Drer\tmem177 - "Cele\R144.12, Cele\R144.11" Xtro\tmem177 Mmus\Tmem177 Hsap\TMEM177 viable FBgn0015526 pdg pigment cell degeneration http://flybase.org/reports/FBgn0015526 - gene - - - pdg - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263533 mir-4973 mir-4973 stem loop http://flybase.org/reports/FBgn0263533 miRNA_gene - - - "mir-4973, dme-mir-4973, CR43518" - CR43518 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0051576 tRNA:Ala-AGC-2-10 transfer RNA:Alanine-AGC 2-10 http://flybase.org/reports/FBgn0051576 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna17-AlaAGC, tRNA:A:AGC:AE002708-e, CR31576, tRNA[[Ala]], chr3R.trna23-AlaAGC, tRNA-Ala-AGC-2-10, tRNA:Ala-AGC-2-10, tRNA:CR31576, GCU" - CR31576 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038890 CG7956 - http://flybase.org/reports/FBgn0038890 protein_coding_gene phosphoric ester hydrolase activity ; GO:0042578 | inferred from electronic annotation with InterPro:IPR002013 - - CG7956 "IPR002013:SAC domain, IPR034753:hSac2 domain, IPR022158:Inositol phosphatase" CG7956 11-Aug-17 DroID_v2017_08 Drer\inpp5f Scer\SAC1 Cele\W09C5.7 Xtro\inpp5f Mmus\Inpp5f Hsap\INPP5F viable FBgn0085454 CG34425 - http://flybase.org/reports/FBgn0085454 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium movement ; GO:0003341 | inferred from electronic annotation with InterPro:IPR033365 cilium assembly ; GO:0060271 | inferred from electronic annotation with InterPro:IPR033365 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34425, CG12584, CG41467" IPR033365:Cilia- and flagella-associated protein 53 CG34425 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037574 Coq2 Coenzyme Q biosynthesis protein 2 http://flybase.org/reports/FBgn0037574 protein_coding_gene 4-hydroxybenzoate octaprenyltransferase activity ; GO:0008412 | inferred from sequence or structural similarity with UniProtKB:Q10252 DNA-directed RNA polymerase activity ; GO:0003899 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q09177 defense response to fungus ; GO:0050832 | inferred from mutant phenotype ubiquinone biosynthetic process ; GO:0006744 | inferred from sequence or structural similarity with UniProtKB:Q10252 transcription from RNA polymerase I promoter ; GO:0006360 | inferred from sequence or structural similarity with UniProtKB:Q09177 insulin-like growth factor receptor signaling pathway ; GO:0048009 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from direct assay defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000537, InterPro:IPR006370 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from sequence or structural similarity with UniProtKB:Q09177 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from sequence or structural similarity with UniProtKB:Q09177 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q10252" "Coq2, CG9613, coq2, COQ2, sbo" "IPR000537:UbiA prenyltransferase family, IPR006370:4-hydroxybenzoate polyprenyltransferase, IPR031103:4-hydroxybenzoate octaprenyltransferase, IPR030470:UbiA prenyltransferase conserved site" CG9613 11-Aug-17 DroID_v2017_08 Drer\coq2 Scer\COQ2 Cele\coq-2 Xtro\coq2 Mmus\Coq2 Hsap\COQ2 "developmental rate defective,small body,long lived,dominant,locomotor rhythm defective,lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage,short lived,visible,somatic clone,immune response defective,viable" "eye,somatic clone,eye disc,trichogen cell" DRSC16516 I -1.524945042 0.318123817 0.30773614 0.429396918 1.231857689 -0.094780411 FBgn0034660 lox2 lysyl oxidase-like 2 http://flybase.org/reports/FBgn0034660 protein_coding_gene scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001190 copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR001695 protein-lysine 6-oxidase activity ; GO:0004720 | inferred from sequence or structural similarity with UniProtKB:Q9Y4K0 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001695 cellular protein modification process ; GO:0006464 | inferred from sequence or structural similarity with UniProtKB:Q9Y4K0 cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with UniProtKB:Q9Y4K0 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001190, InterPro:IPR017448" "Dmloxl-2, dmlox-2, CG4402, lox2" "IPR001190:SRCR domain, IPR001695:Lysyl oxidase, IPR017448:SRCR-like domain" CG4402 11-Aug-17 DroID_v2017_08 "Drer\loxa, Drer\si:dkey-21h14.8, Drer\si:ch211-161n3.3, Drer\loxl4, Drer\loxl2b, Drer\loxl5a, Drer\prss12, Drer\loxl2a, Drer\LOC560447, Drer\si:ch73-127m5.1, Drer\loxl1, Drer\LOC100329480, Drer\marco, Drer\loxl5b, Drer\LOC100536376, Drer\si:dkey-14d8.21, Drer\si:ch211-150o23.3, Drer\scara5, Drer\si:ch211-51a6.2, Drer\si:dkey-14d8.20, Drer\si:dkey-21h14.9, Drer\loxl3b, Drer\loxl3a" - Cele\C06B8.7 "Xtro\prss12, Xtro\lox, Xtro\loxl1, Xtro\loxl4, Xtro\cd163, Xtro\loxl2, Xtro\LOC100497588" "Mmus\5830411N06Rik, Mmus\Dmbt1, Mmus\Prss12, Mmus\Cd5, Mmus\Lox, Mmus\Fcrls, Mmus\Ssc4d, Mmus\Msr1, Mmus\5430419D17Rik, Mmus\Ssc5d, Mmus\Gm21451, Mmus\Loxl3, Mmus\Scara5, Mmus\Loxl2, Mmus\Cd5l, Mmus\Loxl4, Mmus\Loxl1, Mmus\Cd163, Mmus\Cd6, Mmus\Cd163l1, Mmus\Marco" "Hsap\LOXL3, Hsap\CD163, Hsap\PRSS12, Hsap\SCARA5, Hsap\SSC4D, Hsap\CD6, Hsap\SSC5D, Hsap\CD5, Hsap\LOXL1, Hsap\LOX, Hsap\DMBT1, Hsap\LOXL2, Hsap\LOXL4, Hsap\CD5L, Hsap\MARCO, Hsap\CD163L1, Hsap\MSR1" adult stage organism

viable FBgn0047135 CG32276 - http://flybase.org/reports/FBgn0047135 protein_coding_gene - protein glycosylation ; GO:0006486 | inferred from biological aspect of ancestor with PANTHER:PTN000400928 endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from biological aspect of ancestor with PANTHER:PTN000400928 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000400928 "BcDNA:RE27904, CG32276" IPR010580:Stress-associated endoplasmic reticulum protein CG32276 11-Aug-17 DroID_v2017_08 "Drer\serp2, Drer\zgc:85858, Drer\zgc:92744, Drer\serp1" Scer\YSY6 "Cele\T09A12.5, Cele\F59F4.2" "Xtro\serp2, Xtro\serp1" "Mmus\Serp1, Mmus\Serp2" "Hsap\SERP1, Hsap\SERP2" "viable,fertile" FBgn0010032 E(Dl)KP420 Enhancer of Delta KP420 http://flybase.org/reports/FBgn0010032 - gene - - - E(Dl)KP420 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0260277 GSd415 - http://flybase.org/reports/FBgn0260277 gene - - - GSd415 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0065755 l(2)SH0489 lethal (2) SH0489 http://flybase.org/reports/FBgn0065755 gene - - - "l(2)SH0489, l(2)SH2 0489" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069989 BG02058 BG02058 http://flybase.org/reports/FBgn0069989 gene - - - BG02058 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0085229 CG34200 - http://flybase.org/reports/FBgn0085229 protein_coding_gene - - - "CG34200, Dm_2R:4171" - CG34200 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002036 CG10561 - http://flybase.org/reports/FBgn0002036 "FBgn0026744, FBgn0026745, FBgn0043051" protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" cytoplasm ; GO:0005737 | inferred from direct assay "cs, ORF3, ORF2, ORF1, l(2)37Cs, Cs, TuC1, TU37C2, C2, anon-37Cc, anon-37Cb, anon-37Cs, TU37C1, anon-37Cd, CG10561" "IPR002937:Amine oxidase, IPR023753:FAD/NAD(P)-binding domain" CG10561 11-Aug-17 DroID_v2017_08 "Drer\zgc:66484, Drer\kdm1a, Drer\paox1, Drer\smox, Drer\si:dkey-275b16.2" Scer\FMS1 "Cele\hpo-15, Cele\amx-3, Cele\amx-2" "Xtro\LOC100145496, Xtro\smox, Xtro\paox, Xtro\kdm1a" "Mmus\Kdm1a, Mmus\Paox, Mmus\Smox" "Hsap\SMOX, Hsap\KDM1A, Hsap\PAOX" " adult stage , adult stage | female , embryonic stage , larval stage | third instar , adult stage | male " " ovary

, adult head

, adult thorax

, adult abdomen

, testis

" "viable,fertile" FBgn0065348 l(2)SH1810 lethal (2) SH1810 http://flybase.org/reports/FBgn0065348 gene - - - "l(2)SH1810, l(2)SH2 1810" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0040125 l(2)23CDc lethal (2) 23CDc http://flybase.org/reports/FBgn0040125 gene - - - l(2)23CDc - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0085668 CG41524 - http://flybase.org/reports/FBgn0085668 protein_coding_gene - - - CG41524 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259521 B2002 - http://flybase.org/reports/FBgn0259521 gene - - - B2002 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,arista" FBgn0025470 qkr58E-7 quaking related 58E-7 http://flybase.org/reports/FBgn0025470 - gene - - - "qrk58E-7, qkr58E-7" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0061132 l(3)S002302 lethal (3) S002302 http://flybase.org/reports/FBgn0061132 gene - - - "0252/47, 0123/11, 0081/36, 0023/02, l(3)S025247, l(3)S012311, l(3)S008136, l(3)S002302" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0082368 EP3367 EP3367 http://flybase.org/reports/FBgn0082368 gene - - - EP3367 - - 11-Aug-17 DroID_v2017_08 - - - - - - "germline cell,male" FBgn0034426 CG10476 - http://flybase.org/reports/FBgn0034426 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 CG10476 IPR016181:Acyl-CoA N-acyltransferase CG10476 11-Aug-17 DroID_v2017_08 - - "Cele\R05H10.7, Cele\anat-1, Cele\M7.12, Cele\R05H10.1, Cele\W02D7.5, Cele\W02D7.4, Cele\M7.8, Cele\T10B5.4" - - - FBgn0267191 CR45631 - http://flybase.org/reports/FBgn0267191 non_protein_coding_gene - - - CR45631 - CR45631 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0281840 corset corset http://flybase.org/reports/FBgn0281840 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - corset - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038290 CG6912 - http://flybase.org/reports/FBgn0038290 protein_coding_gene - - - "anon-WO0140519.208, anon-WO0118547.571, CG6912" - CG6912 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC16132 EK 0.148206363 0.501328654 -1.898239973 0.219199093 -0.161911793 1.535408873 FBgn0046635 anon-38E.17 anon-38E.17 http://flybase.org/reports/FBgn0046635 gene - - - "38E.17, anon-38E.17" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0050257 tRNA:Thr-TGT-2-1 transfer RNA:Threonine-TGT 2-1 http://flybase.org/reports/FBgn0050257 tRNA_gene ACA codon-amino acid adaptor activity ; GO:0033439 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033439 cytosol ; GO:0005829 | inferred by curator from GO:0033439 "AE002787.trna32-ThrTGT, tRNA[Thr][[3]], tRNA:thr3:47F, tRNA:T3:47F, tRNA:T:TGT:AE002787-c, CR30257, tRNA[[Thr]], chr2R.trna14-ThrTGT, tRNA-Thr-TGT-2-1, tRNA:Thr-TGT-2-1, tRNA:CR30257, ACA" - CR30257 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038095 Cyp304a1 Cyp304a1 http://flybase.org/reports/FBgn0038095 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CYP304A1-Dm, 304a1, CG7241, BcDNA:LP06355, Cyp304a1, Cyp304A1, CYP304a1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG7241 11-Aug-17 DroID_v2017_08 "Drer\cyp2x9, Drer\cyp2u1, Drer\cyp2aa12, Drer\si:zfos-411a11.2, Drer\si:dkey-286h2.7, Drer\cyp2k16, Drer\cyp2x7, Drer\cyp2k19, Drer\cyp2k20, Drer\cyp17a1, Drer\cyp2aa11, Drer\cyp2aa3, Drer\cyp2p8, Drer\cyp2aa2, Drer\cyp2ae1, Drer\cyp2k17, Drer\cyp1b1, Drer\cyp2k31, Drer\cyp2k22, Drer\cyp2p7, Drer\cyp2aa4, Drer\cyp2k8, Drer\cyp2x8, Drer\cyp2ad2, Drer\cyp2k18, Drer\cyp2aa8, Drer\cyp2aa9, Drer\cyp2k6, Drer\cyp2x10.2, Drer\cyp2n13, Drer\cyp2ad6, Drer\cyp2r1, Drer\cyp2x12, Drer\cyp2y3, Drer\cyp2p6, Drer\LOC100148115, Drer\cyp17a2, Drer\cyp2aa1, Drer\cyp21a2, Drer\cyp2k21, Drer\cyp2x6, Drer\cyp2j20, Drer\cyp1d1, Drer\cyp1a" - "Cele\cyp-33C1, Cele\cyp-33A1, Cele\cyp-33D1, Cele\cyp-33D3" "Xtro\cyp2c8.2, Xtro\LOC100497460, Xtro\cyp2u1, Xtro\LOC100493194, Xtro\LOC100145695, Xtro\LOC100145084, Xtro\cyp2w1, Xtro\cyp1d1, Xtro\MGC69353, Xtro\cyp2a6, Xtro\cyp2a13, Xtro\cyp2b6, Xtro\cyp2d6, Xtro\MGC69416, Xtro\LOC548374, Xtro\cyp2r1, Xtro\cyp2c8.1, Xtro\LOC100497184, Xtro\cyp2g1p, Xtro\LOC619584, Xtro\cyp1a1, Xtro\cyp2j2, Xtro\LOC100145323, Xtro\cyp2e1, Xtro\cyp2f2, Xtro\MGC107969, Xtro\cyp17a1, Xtro\LOC100036663, Xtro\LOC100145541, Xtro\cyp21a2.1, Xtro\cyp1b1, Xtro\LOC100486127" "Mmus\Cyp2j12, Mmus\Cyp2j11, Mmus\Cyp2b10, Mmus\Cyp2b9, Mmus\Cyp2b13, Mmus\Cyp2c39, Mmus\Cyp2j8, Mmus\Cyp2c38, Mmus\Cyp2j13, Mmus\Cyp2c40, Mmus\Cyp2d10, Mmus\Cyp2d34, Mmus\Cyp2c37, Mmus\Cyp2f2, Mmus\Cyp2b19, Mmus\Cyp2c68, Mmus\Cyp2j9, Mmus\Cyp2t4, Mmus\Cyp2r1, Mmus\Cyp2c66, Mmus\Cyp2w1, Mmus\Cyp2a5, Mmus\Cyp2c44, Mmus\Cyp2c29, Mmus\Cyp2c54, Mmus\Cyp2a12, Mmus\Cyp2c65, Mmus\Cyp1a2, Mmus\Cyp1b1, Mmus\Cyp2c67, Mmus\Cyp2j5, Mmus\Cyp2c70, Mmus\Cyp2c69, Mmus\Cyp2g1, Mmus\Cyp2s1, Mmus\Cyp2c55, Mmus\Cyp2c50, Mmus\Cyp2a4, Mmus\Cyp21a1, Mmus\Cyp2e1, Mmus\Cyp2d9, Mmus\Cyp2d22, Mmus\Cyp17a1, Mmus\Cyp1a1, Mmus\Cyp2d11, Mmus\Cyp2a22, Mmus\Cyp2j6, Mmus\Cyp2d40, Mmus\Cyp2d26, Mmus\Cyp2ab1, Mmus\Cyp2d12, Mmus\Cyp2b23, Mmus\Cyp2u1" "Hsap\CYP2C9, Hsap\CYP17A1, Hsap\CYP2C18, Hsap\CYP2W1, Hsap\CYP2S1, Hsap\CYP1B1, Hsap\CYP21A2, Hsap\CYP2B6, Hsap\CYP2R1, Hsap\CYP2D6, Hsap\CYP2F1, Hsap\CYP2C19, Hsap\CYP1A2, Hsap\CYP2U1, Hsap\CYP1A1, Hsap\CYP2C8, Hsap\CYP2E1, Hsap\CYP2A13, Hsap\CYP2A7, Hsap\CYP2J2, Hsap\CYP2A6" "fertile,viable" DRSC16623 E 0.269554489 -0.466004842 0.256393564 1.938710036 -0.433945256 -0.121090342 FBgn0035552 CG11350 - http://flybase.org/reports/FBgn0035552 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG11350, CG1135" "IPR004011:GYR motif, IPR004019:YLP motif" CG11350 11-Aug-17 DroID_v2017_08 Drer\pou2af1 - Cele\F11E6.3 - Mmus\Pou2af1 Hsap\POU2AF1 "visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC08181 K -1.050918125 -0.098297352 -0.159072562 -0.214522969 -1.503847229 1.242225675 FBgn0070044 3R-196-22 3R-196-22 http://flybase.org/reports/FBgn0070044 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-196-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal phenotype,germline clone,maternal effect,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,denticle belt" FBgn0052420 tRNA:Val-TAC-1-1 transfer RNA:Valine-TAC 1-1 http://flybase.org/reports/FBgn0052420 tRNA_gene GUA codon-amino acid adaptor activity ; GO:0033451 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033451 cytosol ; GO:0005829 | inferred by curator from GO:0033451 "AE002602.trna14-ValTAC, valine tRNA, tRNA[Val][[3a]], tRNA:val3a:64D, tRNA:V3a:64D, tRNA:V3a, tRNA:V:TAC:AE002602-b, CR32420, chr3L.trna20-ValTAC, tRNA-Val[UAC], tRNA:Val-TAC-1-1, tRNA:CR32420, tRNA-Val-TAC-1-1, GUA" - CR32420 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266912 CR45372 - http://flybase.org/reports/FBgn0266912 non_protein_coding_gene - - - CR45372 - CR45372 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083245 EB5 EB5 http://flybase.org/reports/FBgn0083245 gene - - - EB5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020351 anon-43AB anon-43AB http://flybase.org/reports/FBgn0020351 - gene - - - "555, anon-43AB" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005633 fln flightin http://flybase.org/reports/FBgn0005633 FBgn0010036 protein_coding_gene structural molecule activity conferring elasticity ; GO:0097493 | inferred from mutant phenotype structural constituent of muscle ; GO:0008307 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype striated muscle myosin thick filament assembly ; GO:0071688 | inferred from direct assay skeletal muscle myosin thick filament assembly ; GO:0030241 | inferred from mutant phenotype oscillatory muscle contraction ; GO:0014703 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype striated muscle myosin thick filament ; GO:0005863 | inferred from direct assay A band ; GO:0031672 | inferred from direct assay "mp27, Ftn, CG7445, fln, Fln, flightin" - CG7445 11-Aug-17 DroID_v2017_08 - - - - - - " pupal stage , adult stage " indirect flight muscle

" adult stage , pupal stage " indirect flight muscle

"flightless,visible,viable,fertile,recessive,flight defective,locomotor behavior defective" "sarcomere, with fln0,M band, with fln0,A band, with fln0,indirect flight muscle,myofibril, with fln0,wing,dorsal medial muscle,dorsal medial muscle & myofibril,dorsal medial muscle & sarcomere,dorsal medial muscle & striated muscle thick filament,dorsal medial muscle & striated muscle thin filament,indirect flight muscle & striated muscle thick filament,indirect flight muscle & sarcomere,indirect flight muscle & Z disc,indirect flight muscle & striated muscle thin filament,indirect flight muscle & myofibril,indirect flight muscle & muscle tendon junction,sarcomere, with fln‘îC44.Act88F,M band, with fln‘îC44.Act88F,A band, with fln‘îC44.Act88F,myofibril, with fln‘îC44.Act88F" FBgn0032265 CG18301 - http://flybase.org/reports/FBgn0032265 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" - - CG18301 "IPR025483:Lipase, eukaryotic, IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG18301 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH2, Scer\TGL1, Scer\YEH1" "Cele\lipl-3, Cele\lipl-2, Cele\lipl-1, Cele\lipl-8, Cele\lipl-5, Cele\lipl-6, Cele\lipl-4, Cele\lipl-7" Xtro\lipa "Mmus\Lipa, Mmus\Lipo4, Mmus\Lipo2, Mmus\Lipo1, Mmus\Lipk, Mmus\Lipn, Mmus\Lipo3, Mmus\Lipm, Mmus\Lipf" "Hsap\LIPA, Hsap\LIPM, Hsap\LIPN, Hsap\LIPJ, Hsap\LIPF, Hsap\LIPK" viable FBgn0003913 tyw tiny wing http://flybase.org/reports/FBgn0003913 - gene - - - tyw - - 11-Aug-17 DroID_v2017_08 - - - - - - partially lethal - majority live "wing,posterior scutellar bristle,macrochaeta,head,thorax" FBgn0261697 tctn tectonic http://flybase.org/reports/FBgn0261697 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of smoothened signaling pathway ; GO:0008589 | inferred from sequence or structural similarity with MGI:MGI:3603820 sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype ciliary transition zone ; GO:0035869 | inferred from direct assay MKS complex ; GO:0036038 | inferred from sequence or structural similarity with MGI:MGI:3603820 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with MGI:MGI:3603820 "CG42731, tectonic, CG9227, Tectonic, tctn" IPR011677:Domain of unknown function DUF1619 CG42731 11-Aug-17 DroID_v2017_08 "Drer\b9d2, Drer\tctn1, Drer\tctn2" - Cele\tctn-1 "Xtro\tctn2, Xtro\b9d2" "Mmus\Tctn3, Mmus\Tctn2, Mmus\B9d2, Mmus\Tctn1" "Hsap\TCTN1, Hsap\B9D2, Hsap\TCTN3, Hsap\TCTN2" FBgn0031929 CG18585 - http://flybase.org/reports/FBgn0031929 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG18585 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG18585 11-Aug-17 DroID_v2017_08 "Drer\cpa6, Drer\cpb2, Drer\cpa2, Drer\cpb1, Drer\cpa4, Drer\cpa1, Drer\cpa5, Drer\cpo" Scer\ECM14 "Cele\Y47G6A.19, Cele\T06A4.3, Cele\suro-1, Cele\ZC434.9, Cele\F02D8.4, Cele\W01A8.6, Cele\T06A4.1, Cele\Y18H1A.9, Cele\Y59C2A.1" "Xtro\cpb1, Xtro\cpo, Xtro\cpa1, Xtro\LOC100487462, Xtro\cpa3, Xtro\cpb2" "Mmus\Cpa3, Mmus\Cpa6, Mmus\Cpa5, Mmus\Cpa1, Mmus\Cpb1, Mmus\Cpb2, Mmus\Cpa4, Mmus\Cpa2" "Hsap\CPA6, Hsap\CPA1, Hsap\CPA4, Hsap\CPA5, Hsap\CPO, Hsap\CPA2, Hsap\CPA3, Hsap\CPB1, Hsap\CPB2" viable FBgn0266153 CR44859 - http://flybase.org/reports/FBgn0266153 non_protein_coding_gene - - - CR44859 - CR44859 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005169 l(2)G566 lethal (2) G566 http://flybase.org/reports/FBgn0005169 - gene - - - l(2)G566 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0004703 l(2)56Fe lethal (2) 56Fe http://flybase.org/reports/FBgn0004703 - gene - - - "l(2)56F, l(2)56Fe" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069144 mcl(3)Z4141 mcl(3)Z4141 http://flybase.org/reports/FBgn0069144 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z4141 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0002828 ms(2)E7 male sterile (2) E7 http://flybase.org/reports/FBgn0002828 - gene - - - "ms2.7, ms(2)2.7, ms(2)E7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0063405 l(3)CG2 lethal (3) CG2 http://flybase.org/reports/FBgn0063405 gene - - - l(3)CG2 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023159 Su(mg)1-9 Suppressor of modifier of gypsy 1-9 http://flybase.org/reports/FBgn0023159 - gene - - - Su(mg)1-9 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020531 l(3)319.4 lethal (3) 319.4 http://flybase.org/reports/FBgn0020531 - gene - - - l(3)319.4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002905 mus308 mutagen-sensitive 308 http://flybase.org/reports/FBgn0002905 - protein_coding_gene "DNA-directed DNA polymerase activity ; GO:0003887 | inferred from electronic annotation with InterPro:IPR001098, InterPro:IPR002298 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001098, InterPro:IPR003583 helicase activity ; GO:0004386 | inferred from sequence or structural similarity DNA-directed DNA polymerase activity ; GO:0003887 | non-traceable author statement DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity" DNA repair ; GO:0006281 | non-traceable author statement double-strand break repair via alternative nonhomologous end joining ; GO:0097681 | inferred from mutant phenotype DNA repair ; GO:0006281 | traceable author statement nucleotide-excision repair ; GO:0006289 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from biological aspect of ancestor with PANTHER:PTN000015249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000015249 "Pol theta, AAF54858, 0443/09, mus-308, Nuc3, CG6019, mus308, Mus308, PolQ, POLQ" "IPR001098:DNA-directed DNA polymerase, family A, palm domain, IPR001650:Helicase, C-terminal, IPR002298:DNA polymerase A, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR012337:Ribonuclease H-like domain" CG6019 11-Aug-17 DroID_v2017_08 "Drer\poln, Drer\helq, Drer\polq" "Scer\SLH1, Scer\SGS1" "Cele\helq-1, Cele\polq-1" "Xtro\helq, Xtro\polq" "Mmus\Polq, Mmus\Helq, Mmus\Poln" "Hsap\POLN, Hsap\HELQ, Hsap\POLQ, Hsap\DDX60" oogenesis stage && adult stage | female ovary

"male sterile,chemical sensitive,DNA repair defective,recessive,visible,radiation sensitive,viable,lethal,female fertile,poor" wing FBgn0263323 CR43404 - http://flybase.org/reports/FBgn0263323 non_protein_coding_gene - - - "CG43404, CR43404, lincRNA.89" - CR43404 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037413 Osi5 Osiris 5 http://flybase.org/reports/FBgn0037413 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi5, CG15590" IPR012464:Protein of unknown function DUF1676 CG15590 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040062 yip4 yippee interacting protein 4 http://flybase.org/reports/FBgn0040062 gene - - - yip4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0052396 CG32396 - http://flybase.org/reports/FBgn0052396 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002453, InterPro:IPR008280, InterPro:IPR017975 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002453 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002453, InterPro:IPR017975 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity" "microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002453, InterPro:IPR017975 microtubule ; GO:0005874 | inferred from sequence or structural similarity" "CT42364, CG8339, CG32396, Tub2B" "IPR000217:Tubulin, IPR002453:Beta tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain, IPR013838:Beta tubulin, autoregulation binding site" CG32396 11-Aug-17 DroID_v2017_08 "Drer\tubb6, Drer\tubb1, Drer\tubb5, Drer\zgc:65894, Drer\tubb2, Drer\tube1, Drer\zgc:153426, Drer\zgc:55461, Drer\tubb4b" Scer\TUB2 "Cele\tbb-6, Cele\tbb-4" "Xtro\tubb3, Xtro\tubb6, Xtro\tubb, Xtro\tubb4a, Xtro\tubb2b, Xtro\tube1, Xtro\tubb4b" "Mmus\Tubb1, Mmus\Tubb2a, Mmus\Tubb6, Mmus\Tubb4a, Mmus\Tubb3, Mmus\Tubb5, Mmus\Tubb2b, Mmus\Tube1, Mmus\Tubb4b" "Hsap\TUBB8, Hsap\TUBB1, Hsap\TUBE1, Hsap\TUBB6, Hsap\TUBB2B, Hsap\TUBAL3, Hsap\TUBB, Hsap\TUBB4A, Hsap\TUBB2A, Hsap\TUBB4B, Hsap\TUBB3" viable FBgn0038250 CG3505 - http://flybase.org/reports/FBgn0038250 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 sleep ; GO:0030431 | inferred from expression pattern" extracellular region ; GO:0005576 | inferred from direct assay "SPH9, proPO-AE, CG3505" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain" CG3505 11-Aug-17 DroID_v2017_08 Drer\f10 - "Cele\svh-1, Cele\try-1" - Mmus\Klk1b5 - viable FBgn0010183 tu(2)K tu(2)K http://flybase.org/reports/FBgn0010183 - gene - - - tu(2)K - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261709 CR42746 - http://flybase.org/reports/FBgn0261709 non_protein_coding_gene - - - CR42746 - CR42746 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062606 Mod(var)1367 Mod(var)1367 http://flybase.org/reports/FBgn0062606 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1367, Mod(var)1367" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0014055 Su(tor)2-399 Su(tor)2-399 http://flybase.org/reports/FBgn0014055 - gene - - - Su(tor)2-399 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262191 mir-2497 mir-2497 stem loop http://flybase.org/reports/FBgn0262191 miRNA_gene - - - "dme-mir-2497, mir-2497, CR42898, miR-2497" - CR42898 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0267509 5.8SrRNA-Psi:CR45849 5.8S ribosomal RNA pseudogene:CR45849 http://flybase.org/reports/FBgn0267509 pseudogene_attribute - - - "5.8SrRNA-Psi:CR45849, CR45849" - CR45849 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065573 l(2)SH0956 lethal (2) SH0956 http://flybase.org/reports/FBgn0065573 gene - - - "l(2)SH0956, l(2)SH2 0956" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015221 Fer2LCH Ferritin 2 light chain homologue http://flybase.org/reports/FBgn0015221 "FBgn0010705, FBgn0011018, FBgn0011321, FBgn0011490, FBgn0011491, FBgn0026287, FBgn0039763" protein_coding_gene "ferric iron binding ; GO:0008199 | inferred from electronic annotation with InterPro:IPR001519, InterPro:IPR008331 iron ion binding ; GO:0005506 | inferred from biological aspect of ancestor with PANTHER:PTN000153092 ferrous iron binding ; GO:0008198 | inferred from direct assay" intracellular sequestering of iron ion ; GO:0006880 | inferred from biological aspect of ancestor with PANTHER:PTN000153092 locomotor rhythm ; GO:0045475 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp cellular iron ion homeostasis ; GO:0006879 | inferred from direct assay response to fungus ; GO:0009620 | inferred from expression pattern iron ion import into cell ; GO:0097459 | inferred from mutant phenotype hemolymph coagulation ; GO:0042381 | inferred from expression pattern detoxification of iron ion ; GO:1990461 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000153092 intracellular ferritin complex ; GO:0008043 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG1469, LCH, 2LCH, l(3)07016, l(3)00035, l(3)neo60, l(3)neo63, l(3)s2083, l(3)j2A3, anon-EST:ParkEST264, Fer-H, Fer2LCH, Fe2LCH, fer2lch, Fer2LC, fer2, FerLCH, Fer2" "IPR008331:Ferritin/DPS protein domain, IPR009040:Ferritin-like diiron domain, IPR009078:Ferritin-like superfamily, IPR012347:Ferritin-related, IPR001519:Ferritin" CG1469 11-Aug-17 DroID_v2017_08 "Drer\zgc:56095, Drer\fth1b, Drer\zgc:172145, Drer\fth1a" - "Cele\ftn-2, Cele\ftn-1" - "Mmus\Gm813, Mmus\Fthl17c, Mmus\Fthl17e, Mmus\Ftmt, Mmus\Fth1, Mmus\Fthl17a, Mmus\Fthl17b, Mmus\Fthl17f, Mmus\E330017A01Rik" "Hsap\FTHL17, Hsap\FTMT, Hsap\FTH1" "lethal,viable,fertile,recessive,developmental rate defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,locomotor rhythm defective,circadian rhythm defective,gravitaxis defective,progressive" DRSC16672 K 0.290855981 -0.32930079 -0.942798565 -0.540428811 -2.349865675 -2.256859738 FBgn0263573 mir-4942 mir-4942 stem loop http://flybase.org/reports/FBgn0263573 miRNA_gene - - - "mir-4942, dme-mir-4942, CR43558" - CR43558 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042137 CG18814 - http://flybase.org/reports/FBgn0042137 protein_coding_gene "alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from electronic annotation with InterPro:IPR002424, InterPro:IPR002425" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002424, InterPro:IPR002425 alcohol metabolic process ; GO:0006066 | inferred from electronic annotation with InterPro:IPR002425" - CG18814 "IPR016040:NAD(P)-binding domain, IPR002424:Alcohol dehydrogenase, insect-type, IPR002425:Alcohol dehydrogenase, Drosophila-type, IPR020904:Short-chain dehydrogenase/reductase, conserved site, IPR002347:Short-chain dehydrogenase/reductase SDR" CG18814 11-Aug-17 DroID_v2017_08 "Drer\hpgd, Drer\cbr4, Drer\zgc:56585" Scer\SPS19 "Cele\C06B8.3, Cele\T01G6.1, Cele\C01G12.5, Cele\T01G6.10, Cele\W03F9.9, Cele\R05D8.9" Xtro\hpgd "Mmus\Hpgd, Mmus\Cbr4" "Hsap\HPGD, Hsap\CBR4" viable FBgn0051888 tRNA:Asp-GTC-1-9 transfer RNA:Aspartic acid-GTC 1-9 http://flybase.org/reports/FBgn0051888 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "AE002690.trna21-AspGTC, tRNA:asp2:29E, tRNA:D2:29E, tRNA:D:GTC:AE002690-e, CR31888, tRNA[[Asp]], tRNA, tRNA[Asp-GTC], chr2L.trna30-AspGTC, tRNA:Asp-GTC-1-9, tRNA:CR31888, tRNA-Asp-GTC-1-9, GAC" - CR31888 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062613 Mod(var)1294 Mod(var)1294 http://flybase.org/reports/FBgn0062613 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1294, Mod(var)1294" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0044413 Scim14 Sensitized chromosome inheritance modifier 14 http://flybase.org/reports/FBgn0044413 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0029048 l(1)G0473 lethal (1) G0473 http://flybase.org/reports/FBgn0029048 gene - - - l(1)G0473 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal,recessive" FBgn0034121 CG6262 - http://flybase.org/reports/FBgn0034121 protein_coding_gene "alpha,alpha-trehalase activity ; GO:0004555 | inferred from electronic annotation with InterPro:IPR001661" trehalose metabolic process ; GO:0005991 | inferred from electronic annotation with InterPro:IPR001661 - CG6262 "IPR001661:Glycoside hydrolase, family 37, IPR008928:Six-hairpin glycosidase-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG6262 11-Aug-17 DroID_v2017_08 Drer\treh "Scer\NTH2, Scer\NTH1" "Cele\tre-1, Cele\tre-3, Cele\tre-2, Cele\tre-4, Cele\tre-5" Xtro\treh Mmus\Treh Hsap\TREH viable FBgn0265579 CG44406 - http://flybase.org/reports/FBgn0265579 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44406 - CG44406 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020349 anon-44CDa anon-44CDa http://flybase.org/reports/FBgn0020349 - gene - - - "536, anon-44CDa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005289 mei-1966 meiotic 1966 http://flybase.org/reports/FBgn0005289 - gene - - - "1966, mei-1966" - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0026615 10-4 10-4 http://flybase.org/reports/FBgn0026615 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available - 10-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040561 CG14844 - http://flybase.org/reports/FBgn0040561 protein_coding_gene - - - CG14844 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005663 dodeca dodeca http://flybase.org/reports/FBgn0005663 - repeat_region - - - "dodecasatellite, Dodeca, dodeca" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266469 nuss - http://flybase.org/reports/FBgn0266469 gene - - - nuss - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,cell polarity defective,germline clone" "egg chamber,germline clone,oocyte,centrosome | germline clone" FBgn0085666 CG41521 - http://flybase.org/reports/FBgn0085666 protein_coding_gene - - - CG41521 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028210 l(3)S011004 lethal (3) S011004 http://flybase.org/reports/FBgn0028210 gene - - - "0110/04, l(3)S011004" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0034327 CG14505 - http://flybase.org/reports/FBgn0034327 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14505 "IPR007967:Protein of unknown function DUF727, IPR023231:GSKIP domain" CG14505 11-Aug-17 DroID_v2017_08 Drer\gskip - "Cele\T24H7.3, Cele\C06A12.3, Cele\Y43F8B.2" Xtro\gskip Mmus\Gskip Hsap\GSKIP viable FBgn0039694 fig fos intronic gene http://flybase.org/reports/FBgn0039694 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000001118 phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000001118 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence model protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with UniProtKB:P35813 protein dephosphorylation ; GO:0006470 | inferred by curator from GO:0004722 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000001118 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with UniProtKB:P35813 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000268440 "CG7615, fig" IPR001932:PPM-type phosphatase domain CG7615 11-Aug-17 DroID_v2017_08 "Drer\pptc7b, Drer\pptc7a" Scer\PTC7 Cele\W09D10.4 Xtro\pptc7 Mmus\Pptc7 Hsap\PPTC7 "partially lethal - majority die,some die during pupal stage" FBgn0031747 CG9021 - http://flybase.org/reports/FBgn0031747 protein_coding_gene - - - CG9021 IPR010629:Insect allergen-related CG9021 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037342 CG2931 - http://flybase.org/reports/FBgn0037342 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "cg2931, CG2931" "IPR000504:RNA recognition motif domain, IPR034215:RBM42, RNA recognition motif" CG2931 11-Aug-17 DroID_v2017_08 Drer\rbm42 Scer\PUB1 Cele\tag-262 Xtro\rbm42 Mmus\Rbm42 "Hsap\HNRNPDL, Hsap\G3BP1, Hsap\RBM42" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,tormogen cell,mesothoracic tergum" DRSC12324 K 1.367713832 0.217355838 0.627371263 0.881955292 -1.792911199 -1.485319361 FBgn0036302 sowah sosondowah http://flybase.org/reports/FBgn0036302 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG10632, BcDNA:GM09162, sowah" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG10632 11-Aug-17 DroID_v2017_08 "Drer\sowahab, Drer\trpa1b, Drer\zdhhc17, Drer\zdhhc13, Drer\sowahca, Drer\sowahd, Drer\sowahcb" "Scer\AKR1, Scer\AKR2, Scer\YAR1" "Cele\dhhc-13, Cele\unc-44, Cele\dhhc-14, Cele\trpa-1" "Xtro\sowahb, Xtro\sowaha, Xtro\sowahc" "Mmus\Ankrd35, Mmus\Ank3, Mmus\Sowaha, Mmus\Sowahb, Mmus\Trpa1, Mmus\Sowahd, Mmus\Zdhhc17, Mmus\Sowahc, Mmus\Ank1, Mmus\Zdhhc13, Mmus\Ank2" "Hsap\ANKRD35, Hsap\ZDHHC13, Hsap\SOWAHB, Hsap\SOWAHA, Hsap\ANK3, Hsap\ZDHHC17, Hsap\ANK2, Hsap\SOWAHC, Hsap\SOWAHD, Hsap\ANK1" "viable,fertile" DRSC09186 I 1.758314236 -0.161173028 0.784277486 0.200808964 0.924051238 -0.248672762 FBgn0020295 kiwi kiwi http://flybase.org/reports/FBgn0020295 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available kiwi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,somatic clone" "wing,somatic clone,larva" FBgn0001675 l(1)EN12 lethal (1) from Eugene Nonautonomous 12 http://flybase.org/reports/FBgn0001675 - gene - - - l(1)EN12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,body color defective" adult cuticle FBgn0060864 l(3)S047324 lethal (3) S047324 http://flybase.org/reports/FBgn0060864 gene - - - "0473/24, l(3)S047324" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035024 CG11414 - http://flybase.org/reports/FBgn0035024 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:28079 zinc ion binding ; GO:0008270 | inferred from sequence model mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG11414 "IPR001841:Zinc finger, RING-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11414 11-Aug-17 DroID_v2017_08 Drer\znf598 Scer\HEL2 Cele\C52E12.1 Xtro\znf598 Mmus\Zfp598 Hsap\ZNF598 viable FBgn0022229 l(2)k03105 lethal (2) k03105 http://flybase.org/reports/FBgn0022229 - gene - - - l(2)k03105 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027157 l(2)T-14.3 lethal (2) T-14.3 http://flybase.org/reports/FBgn0027157 - gene - - - l(2)T-14.3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003086 Pig1 Pre-intermoult gene 1 http://flybase.org/reports/FBgn0003086 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Pig-1, pig1, CG10790, gsg, EG:96G10.1, Pig1" - CG10790 11-Aug-17 DroID_v2017_08 - - - - - - larval stage " embryonic/larval salivary gland

, organism

" viable FBgn0002922 nau nautilus http://flybase.org/reports/FBgn0002922 - protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from biological aspect of ancestor with PANTHER:PTN000164853 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001228 | inferred from biological aspect of ancestor with PANTHER:PTN000164853 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000164853" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002546 muscle organ development ; GO:0007517 | traceable author statement positive regulation of myoblast differentiation ; GO:0045663 | inferred from biological aspect of ancestor with PANTHER:PTN000164853 determination of muscle attachment site ; GO:0016204 | inferred from mutant phenotype regulation of striated muscle tissue development ; GO:0016202 | traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype positive regulation of myoblast fusion ; GO:1901741 | inferred from biological aspect of ancestor with PANTHER:PTN000164853" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "MyoD, MYOD, Dmyd, Mdrf, CG10250, nau, NAU, Nau" "IPR002546:Myogenic basic muscle-specific protein, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG10250 11-Aug-17 DroID_v2017_08 "Drer\myf6, Drer\myog, Drer\myf5, Drer\myod1" - Cele\hlh-1 "Xtro\myod1, Xtro\myf6, Xtro\myf5, Xtro\myog" "Mmus\Myod1, Mmus\Myf6, Mmus\Myog, Mmus\Myf5" "Hsap\MYOG, Hsap\MYF5, Hsap\MYF6, Hsap\MYOD1" " embryonic stage , embryonic stage && larval stage " " somatic mesoderm

{ e bib* } , somatic mesoderm

{ e N* } , larval muscle system

, larval somatic muscle

{ e Dl* } , somatic mesoderm

{ e mam* } , somatic mesoderm

{ e amx* } , somatic mesoderm

{ e Nj* } , somatic mesoderm

{ e neur* } , somatic mesoderm

, somatic mesoderm

{ e E(spl)* } " " embryonic stage | stage >=11 , embryonic stage | stage >=14 " "

segmentally repeated , somatic muscle &&of telson

, pharyngeal muscle

, larval muscle system

, abdominal 1 ventral longitudinal muscle 1

, abdominal 1 ventral acute muscle 2

, abdominal 1 ventral acute muscle 1

, ventral oblique muscle

, abdominal 1--7 ventral oblique muscle 5

, abdominal 1--7 ventral oblique muscle 4

, anterior spiracle retractor muscle

, abdominal 2--7 ventral oblique muscle 6

" "female sterile,viable,sterile,recessive,lethal,flightless,locomotor behavior defective,partially" "A1-7 dorsal oblique muscle 4,abdominal 1 dorsal acute muscle 3,embryonic/larval somatic muscle,presumptive embryonic/larval muscle system,germline clone,A1-7 dorsal acute muscle 3,A1-7 dorsal oblique muscle 3,myoblast,cardioblast,somatic mesoderm,egg,egg chamber,midgut constriction" FBgn0065443 l(2)SH1452 lethal (2) SH1452 http://flybase.org/reports/FBgn0065443 gene - - - "l(2)SH1452, l(2)SH2 1452" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0024516 l(3)j14E7 lethal (3) j14E7 http://flybase.org/reports/FBgn0024516 - gene - - - l(3)j14E7 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0016646 ER3-4 ER3-4 http://flybase.org/reports/FBgn0016646 - gene - - - ER3-4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265837 CR44626 - http://flybase.org/reports/FBgn0265837 non_protein_coding_gene - - - CR44626 - CR44626 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003500 srb smaller body http://flybase.org/reports/FBgn0003500 - gene - - - "sby-62, srb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,female fertile,reduced,size defective" macrochaeta FBgn0037276 CG17387 - http://flybase.org/reports/FBgn0037276 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium movement ; GO:0003341 | inferred from biological aspect of ancestor with PANTHER:PTN000437718 cilium movement ; GO:0003341 | inferred from sequence or structural similarity with HGNC:25244 inner dynein arm assembly ; GO:0036159 | inferred from biological aspect of ancestor with PANTHER:PTN000437718 cilium-dependent cell motility ; GO:0060285 | inferred from biological aspect of ancestor with PANTHER:PTN000437718 axoneme ; GO:0005930 | inferred from sequence or structural similarity with HGNC:25244 axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000437718 CG17387 IPR033290:Coiled-coil domain-containing protein 39 CG17387 11-Aug-17 DroID_v2017_08 Drer\ccdc39 - - "Xtro\ccdc39, Xtro\esd" "Mmus\Esd, Mmus\Ccdc39" "Hsap\CCDC39, Hsap\ESD" viable FBgn0262444 mir-1013 mir-1013 stem loop http://flybase.org/reports/FBgn0262444 miRNA_gene - - - "dme-mir-1013, mir-1013, CR43010, miR-1013, dme-miR-1013" - CR43010 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002829 ms(2)E8 male sterile (2) E8 http://flybase.org/reports/FBgn0002829 - gene - - - "ms2.8, ms(2)2.8, ms(2)E8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0035480 CG14984 - http://flybase.org/reports/FBgn0035480 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14984 - CG14984 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0002792 MRF Male recombination factor http://flybase.org/reports/FBgn0002792 - gene - - - "MRF, MR" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001530 l(1)11Ef lethal (1) 11Ef http://flybase.org/reports/FBgn0001530 - gene - - - l(1)11Ef - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0035393 CG16753 - http://flybase.org/reports/FBgn0035393 protein_coding_gene - - - CG16753 - CG16753 11-Aug-17 DroID_v2017_08 Drer\fam207a - - Xtro\fam207a Mmus\Fam207a Hsap\FAM207A FBgn0014312 l(3)ry107 lethal (3) ry107 http://flybase.org/reports/FBgn0014312 - gene - - - l(3)ry107 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0264631 black-hole black hole http://flybase.org/reports/FBgn0264631 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - black-hole - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval tracheal system,eye,somatic clone,terminal tracheal cell" FBgn0015960 l(2)40Aa lethal (2) 40Aa http://flybase.org/reports/FBgn0015960 - gene - - - l(2)40Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025497 l(3)73Bg lethal (3) 73Bg http://flybase.org/reports/FBgn0025497 - gene - - - l(3)73Bg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043572 S(faf)86 S(faf)86 http://flybase.org/reports/FBgn0043572 gene - - - S(faf)86 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,wild-type" FBgn0263564 mir-4914 mir-4914 stem loop http://flybase.org/reports/FBgn0263564 miRNA_gene - - - "mir-4914, dme-mir-4914, CR43549" - CR43549 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030719 eIF5 eukaryotic translation initiation factor 5 http://flybase.org/reports/FBgn0030719 protein_coding_gene "translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR002735, InterPro:IPR016189, InterPro:IPR016190 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity" "translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR002735, InterPro:IPR016189, InterPro:IPR016190 translational initiation ; GO:0006413 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from sequence or structural similarity "CG9177, anon-EST:fe3C6, eIF5, EIf5" "IPR002735:Translation initiation factor IF2/IF5, IPR003307:W2 domain, IPR016024:Armadillo-type fold, IPR016189:Translation initiation factor IF2/IF5, N-terminal, IPR016190:Translation initiation factor IF2/IF5, zinc-binding" CG9177 11-Aug-17 DroID_v2017_08 Drer\eif5 Scer\TIF5 Cele\C37C3.2 Xtro\eif5 Mmus\Eif5 Hsap\EIF5 "lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective" "ganglion mother cell,embryonic/larval neuroblast" FBgn0065832 l(2)SH0348 lethal (2) SH0348 http://flybase.org/reports/FBgn0065832 gene - - - "l(2)SH0348, l(2)SH2 0348" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263601 mib1 mind bomb 1 http://flybase.org/reports/FBgn0263601 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433, InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with Ser ubiquitin-protein transferase activity ; GO:0004842 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P10041 inferred from physical interaction with UniProtKB:P18168 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay" protein localization ; GO:0008104 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | non-traceable author statement endocytosis ; GO:0006897 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay "CG5841, mib1, l(3)72Db, l(3)72CDa, Dmib, Mib, D-mib, mind-bomb, Mib1, MIB1, dmib1, mib, D-mib1, mib1/2" "IPR000433:Zinc finger, ZZ-type, IPR001841:Zinc finger, RING-type, IPR002110:Ankyrin repeat, IPR010606:Mib-herc2, IPR020683:Ankyrin repeat-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5841 11-Aug-17 DroID_v2017_08 "Drer\LOC555713, Drer\sqstm1, Drer\mib1, Drer\nbr1" Scer\AKR2 Cele\mib-1 "Xtro\mib1, Xtro\sqstm1, Xtro\nbr1, Xtro\mib2" "Mmus\Mib2, Mmus\Nbr1, Mmus\Mib1, Mmus\Sqstm1" "Hsap\MIB2, Hsap\MIB1, Hsap\SQSTM1, Hsap\NBR1" DRSC10550 I 1.116112117 1.524076813 1.119387857 -0.048132077 -0.040790088 -0.247937495 FBgn0015445 l(1)7Do lethal (1) 7Do http://flybase.org/reports/FBgn0015445 - gene - - - l(1)7Do - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060684 l(3)S075901 lethal (3) S075901 http://flybase.org/reports/FBgn0060684 gene - - - "0759/01, l(3)S075901" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014240 l(2)32Aa lethal (2) 32Aa http://flybase.org/reports/FBgn0014240 - gene - - - l(2)32Aa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0259967 Sfp53D Seminal fluid protein 53D http://flybase.org/reports/FBgn0259967 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG42477, Sfp53D, HDC06796" - CG42477 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032435 Oatp33Eb Organic anion transporting polypeptide 33Eb http://flybase.org/reports/FBgn0032435 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from direct assay transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with Oatp58Db active transmembrane transporter activity ; GO:0022804 | inferred from sequence or structural similarity with Oatp58Db organic substance transport ; GO:0071702 | inferred from direct assay organic substance transport ; GO:0071702 | inferred from sequence or structural similarity with Oatp58Db lateral plasma membrane ; GO:0016328 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Oatp58Db "oatp 33Eb, CG6417, Oatp33Eb" "IPR020846:Major facilitator superfamily domain, IPR004156:Organic anion transporter polypeptide OATP, IPR002350:Kazal domain" CG6417 11-Aug-17 DroID_v2017_08 "Drer\LOC100536648, Drer\slco1f4, Drer\slco2a1, Drer\slco2b1, Drer\slco1d1, Drer\slco1c1, Drer\LOC570448, Drer\LOC101883455, Drer\slco1f1, Drer\slco4a1, Drer\slco3a1, Drer\slco1f2, Drer\slco1f3, Drer\LOC100334356, Drer\slco5a1" - "Cele\F47E1.4, Cele\K02G10.5, Cele\Y32F6B.1, Cele\F21G4.1, Cele\F53B1.8, Cele\Y70G10A.3, Cele\F47E1.2" "Xtro\slco2a1, Xtro\slco3a1, Xtro\slco4a1, Xtro\slco1b3, Xtro\slco5a1, Xtro\slco4c1" "Mmus\Slco1c1, Mmus\Slco6d1, Mmus\Slco4c1, Mmus\Slco4a1, Mmus\Slco6c1, Mmus\Slco3a1, Mmus\Slco1b2, Mmus\Slco1a1, Mmus\Slco2b1, Mmus\Gm6614, Mmus\Slco2a1, Mmus\Slco1a4, Mmus\Slco1a6, Mmus\Slco5a1, Mmus\Slco1a5, Mmus\Gm5724" "Hsap\SLCO1C1, Hsap\SLCO2B1, Hsap\SLCO1B1, Hsap\SLCO1B3, Hsap\SLCO4A1, Hsap\SLCO1A2, Hsap\SLCO6A1, Hsap\SLCO3A1, Hsap\SLCO1B7, Hsap\SLCO5A1, Hsap\SLCO4C1, Hsap\SLCO2A1" viable FBgn0065130 l(3)SH133 lethal (3) SH133 http://flybase.org/reports/FBgn0065130 gene - - - "l(3)SH133, l(2)SH3 133" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015799 Rbf Retinoblastoma-family protein http://flybase.org/reports/FBgn0015799 - protein_coding_gene RNA polymerase II regulatory region DNA binding ; GO:0001012 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Dp inferred from physical interaction with E2f1 inferred from physical interaction with E2f2 transcription factor binding ; GO:0008134 | inferred from physical interaction with Dp inferred from physical interaction with E2f1 protein binding ; GO:0005515 | inferred from physical interaction with Snr1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O77051 transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay eggshell chorion gene amplification ; GO:0007307 | traceable author statement negative regulation of cell proliferation ; GO:0008285 | non-traceable author statement mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay regulation of cohesin loading ; GO:0071922 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype regulation of execution phase of apoptosis ; GO:1900117 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype regulation of chromosome segregation ; GO:0051983 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | inferred from mutant phenotype endomitotic cell cycle ; GO:0007113 | traceable author statement intrinsic apoptotic signaling pathway in response to DNA damage ; GO:0008630 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from genetic interaction with Rbf2 negative regulation of DNA replication ; GO:0008156 | inferred from mutant phenotype maintenance of mitotic sister chromatid cohesion ; GO:0034088 | inferred from mutant phenotype regulation of DNA binding ; GO:0051101 | inferred from direct assay regulation of cell death ; GO:0010941 | inferred from mutant phenotype chromatin ; GO:0000785 | inferred from direct assay Rb-E2F complex ; GO:0035189 | inferred from direct assay Myb complex ; GO:0031523 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay Rb-E2F complex ; GO:0035189 | traceable author statement "Rbf, RBF1, rbf, Rbf1, Rb, rb, rbf1, RBF, RbF, EG:34F3.3, CG7413, dRBF, Rb1, FBF, pRb, RB, RBf1" "IPR002719:Retinoblastoma-associated protein, B-box, IPR002720:Retinoblastoma-associated protein, A-box, IPR013763:Cyclin-like, IPR024599:Retinoblastoma-associated protein, N-terminal, IPR028309:Retinoblastoma protein family" CG7413 11-Aug-17 DroID_v2017_08 "Drer\rbl1, Drer\rb1, Drer\rbl2" - Cele\lin-35 "Xtro\rbl1, Xtro\rbl2" "Mmus\Rbl2, Mmus\Rbl1, Mmus\Rb1" "Hsap\RB1, Hsap\RBL1, Hsap\RBL2" "viable,fertile,sterile,increased cell death,recessive,somatic clone,cell growth defective,increased cell number,visible,wild-type,lethal,germline clone,rescuable maternal effect,some die during second instar larval stage,some die during third instar larval stage,some die during pupal stage,lethal - all die before end of pupal stage,mitotic cell cycle defective,neuroanatomy defective,decreased cell number,developmental rate defective,immune response defective,partially" "chorion,follicle cell & cell cycle,S phase | ectopic & eye disc | posterior,eye disc,eye,follicle cell,mitotic cell cycle,somatic clone,eye disc anterior to the morphogenetic furrow,morphogenetic furrow,ommatidium,eye disc posterior to the morphogenetic furrow,interommatidial bristle,pigment cell,ectopic,scutellar bristle,embryonic epidermis,embryonic/larval midgut primordium,embryonic epidermis & S phase | germ-line clone,S phase | ectopic,embryonic epidermis & S phase,wing disc,cone cell,eye photoreceptor cell,wing margin,mitotic cell cycle | somatic clone,submarginal cell,anterior crossvein,wing,posterior compartment,abdomen,chaeta,mesothoracic tergum" FBgn0040618 CG14063 - http://flybase.org/reports/FBgn0040618 protein_coding_gene - - - CG14063 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010656 l(2)09639 lethal (2) 09639 http://flybase.org/reports/FBgn0010656 - gene - - - l(2)09639 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0023153 Su(mg)2-6 Suppressor of modifier of gypsy 2-6 http://flybase.org/reports/FBgn0023153 - gene - - - Su(mg)2-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031456 Trn-SR Transportin-Serine/Arginine rich http://flybase.org/reports/FBgn0031456 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 protein binding ; GO:0005515 | inferred from physical interaction with B52 inferred from physical interaction with x16 inferred from physical interaction with Rbp1 inferred from physical interaction with SC35 inferred from physical interaction with SF2 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 "splicing factor protein import into nucleus ; GO:0035048 | inferred from direct assay inferred from physical interaction with B52 inferred from physical interaction with x16 inferred from physical interaction with Rbp1 inferred from physical interaction with SC35 inferred from physical interaction with SF2 protein import into nucleus ; GO:0006606 | inferred from sequence or structural similarity with SGD:S000005686 regulation of mRNA splicing, via spliceosome ; GO:0048024 | inferred from physical interaction with B52 inferred from physical interaction with x16 inferred from physical interaction with Rbp1 inferred from physical interaction with SC35 inferred from physical interaction with SF2 neurogenesis ; GO:0022008 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 nucleus ; GO:0005634 | inferred from direct assay "CG2848, dTRN-SR, anon-EST:Posey294, Trn-SR, TNPO3" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR013598:Exportin-1/Importin-beta-like, IPR016024:Armadillo-type fold" CG2848 11-Aug-17 DroID_v2017_08 Drer\tnpo3 "Scer\MTR10, Scer\KAP122" "Cele\T16G12.6, Cele\tsr-1" Xtro\tnpo3 Mmus\Tnpo3 Hsap\TNPO3 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,embryonic/larval neuroblast,trichogen cell,mesothoracic tergum" FBgn0026092 E(lt[v])319 E(lt[v])319 http://flybase.org/reports/FBgn0026092 - gene - - - E(lt[v])319 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0050081 Ir51b Ionotropic receptor 51b http://flybase.org/reports/FBgn0050081 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir51b, IR51b, DmelIR51b, CG30081" - CG30081 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0031090 Rab35 Rab35 http://flybase.org/reports/FBgn0031090 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 phagocytosis ; GO:0006909 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 exosomal secretion ; GO:1990182 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 lipid particle ; GO:0005811 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 plasma membrane ; GO:0005886 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay "DRab35, DmRab35, dRab35, CG9575, Rab35, rab35, Q95RH7" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9575 11-Aug-17 DroID_v2017_08 "Drer\rab35b, Drer\rab10, Drer\rab8b, Drer\ift27, Drer\rab35a, Drer\zgc:171927, Drer\rab1aa, Drer\rab1ab, Drer\rab8a, Drer\si:dkey-16l2.16, Drer\rab13" "Scer\TEM1, Scer\YPT1" "Cele\rab-35, Cele\rab-8, Cele\rab-1" "Xtro\rab8b, Xtro\rab8a, Xtro\rab35, Xtro\rab35, Xtro\rab13, Xtro\rab1a" "Mmus\Rab1b, Mmus\Ift27, Mmus\Rab8b, Mmus\Rab35, Mmus\Rab1a, Mmus\Rab13, Mmus\Rab10, Mmus\Rab8a" "Hsap\RAB13, Hsap\RAB8B, Hsap\RAB10, Hsap\IFT27, Hsap\RAB1A, Hsap\RAB35, Hsap\RAB1B" "neurophysiology defective,partially lethal - majority die" embryonic/larval neuromuscular junction FBgn0062653 EP3714 EP3714 http://flybase.org/reports/FBgn0062653 gene - - - "EP(3)3714, EP3714" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0023119 anon-10Ao anon-10Ao http://flybase.org/reports/FBgn0023119 - gene - - - "7, anon-10Ao" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011705 rost rolling stone http://flybase.org/reports/FBgn0011705 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available myoblast fusion ; GO:0007520 | traceable author statement myoblast fusion ; GO:0007520 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from direct assay "CG9552, rost" - CG9552 11-Aug-17 DroID_v2017_08 - - "Cele\srd-56, Cele\C46E10.2" - - - " embryonic stage | stage 16-17 , embryonic stage | 0-4 hr , embryonic stage | early , adult stage && oogenesis stage , embryonic stage | stage 12 , embryonic stage | stage 13-17 , embryonic stage , embryonic stage | >=8-12 hr , adult stage , embryonic stage | stage 12-14 " " gonad | restricted

, nurse cell

, embryonic head

, embryonic central nervous system | restricted

, muscle system | restricted

, embryonic brain | restricted

, mesoderm

segmentally repeated " "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "somatic muscle,myoblast,segment border muscle,ectopic,embryonic/larval somatic muscle,ventral,lateral longitudinal muscle 1,lateral oblique muscle 1" FBgn0260454 CG17139 - http://flybase.org/reports/FBgn0260454 protein_coding_gene channel activity ; GO:0015267 | NOT inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR027246 mitochondrial outer membrane ; GO:0005741 | inferred from electronic annotation with InterPro:IPR027246 "CG31722, CG17139, CG31722-A" IPR027246:Eukaryotic porin/Tom40 CG17139 11-Aug-17 DroID_v2017_08 "Drer\zgc:56235, Drer\vdac1, Drer\vdac2, Drer\LOC101886830, Drer\vdac3" "Scer\POR2, Scer\POR1" Cele\vdac-1 "Xtro\vdac2, Xtro\vdac3, Xtro\vdac1" "Mmus\Vdac2, Mmus\Vdac3, Mmus\Vdac1" "Hsap\VDAC1, Hsap\VDAC2, Hsap\VDAC3" FBgn0013597 l(3)B14.1M3 lethal (3) B14.1M3 http://flybase.org/reports/FBgn0013597 - gene - - - l(3)B14.1M3 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0045035 tefu telomere fusion http://flybase.org/reports/FBgn0045035 protein_coding_gene protein kinase activity ; GO:0004672 | non-traceable author statement histone kinase activity ; GO:0035173 | inferred from direct assay telomere maintenance ; GO:0000723 | inferred from mutant phenotype mitotic cell cycle checkpoint ; GO:0007093 | inferred from genetic interaction with stg mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype negative regulation of glial cell apoptotic process ; GO:0034351 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype phosphorylation ; GO:0016310 | non-traceable author statement meiotic DNA double-strand break processing ; GO:0000706 | inferred from direct assay histone H2A phosphorylation ; GO:1990164 | inferred from direct assay karyosome formation ; GO:0030717 | inferred from direct assay negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs chromatin silencing at telomere ; GO:0006348 | inferred from mutant phenotype response to caffeine ; GO:0031000 | inferred from genetic interaction with MAGE telomere capping ; GO:0016233 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "tefu, dATM, ATM, CG6535, atm, tef, atm/tefu, Tefu, Atm" "IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR003152:FATC domain, IPR011009:Protein kinase-like domain, IPR014009:PIK-related kinase, IPR011989:Armadillo-like helical" CG6535 11-Aug-17 DroID_v2017_08 Drer\atm Scer\TEL1 "Cele\atm-1, Cele\atl-1" Xtro\atm Mmus\Atm Hsap\ATM "neuroanatomy defective,increased cell number,decreased cell death,increased cell death,temperature conditional,locomotor behavior defective,gravitaxis defective,short lived,long lived,visible,somatic clone,DNA repair defective,cell cycle defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage,mitotic cell cycle defective,lethal - all die during pupal stage,female sterile,radiation sensitive,lethal - all die before end of P-stage,majority die during pharate adult stage,lethal,maternal effect,lethal - all die during embryonic stage,non-rescuable maternal effect,viable,heat sensitive,female,male,semidominant,conditional,dominant,progressive,radiation resistant,cell non-autonomous" "rhabdomere of eye photoreceptor cell,eye disc posterior to the morphogenetic furrow | third instar larval stage,eye photoreceptor cell | third instar larval stage,eye,eye photoreceptor cell,temperature conditional,neuropil,lamina,neuron,glial cell,optic lobe,antenna,wing,leg,chaeta,somatic clone,embryonic/larval neuroblast,metaphase & condensed nuclear chromosome,anaphase & condensed nuclear chromosome,chromosome, telomeric region,macrochaeta,wing disc,eye disc,mitosis & nuclear chromosome,cleavage nucleus,germline clone,maternal effect,spindle | germline clone | maternal effect,chorion | germline clone | maternal effect,dorsal appendage,mitosis & nuclear chromosome | maternal effect | germ-line clone,condensed chromosome,chromosome, telomeric region | embryonic stage | maternal effect, with tefuZIII-5190,ommatidium,interommatidial bristle,chromosome & neuroblast | third instar larval stage 2,heat sensitive,adult thorax & chaeta | conditional tsPG4),eye-antennal disc,anterior,karyosome,cell non-autonomous,chromosome, telomeric region | embryonic stage | maternal effect, with tefustg" FBgn0267936 CR46216 - http://flybase.org/reports/FBgn0267936 non_protein_coding_gene - - - "CR46216, lincRNA.620" - CR46216 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0024177 zpg zero population growth http://flybase.org/reports/FBgn0024177 FBgn0035706 protein_coding_gene gap junction hemi-channel activity ; GO:0055077 | non-traceable author statement gap junction channel activity ; GO:0005243 | inferred by curator from GO:0005921 gap junction channel activity ; GO:0005243 | non-traceable author statement spermatogenesis ; GO:0007283 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype intercellular transport ; GO:0010496 | inferred from sequence or structural similarity with Inx3 germ cell development ; GO:0007281 | traceable author statement germ cell development ; GO:0007281 | inferred from mutant phenotype gap junction ; GO:0005921 | inferred from direct assay gap junction ; GO:0005921 | traceable author statement integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay "inx-4, inx4, CG10125, Dm-inx4, zpg, FBpp0076692, Inx4, Zpg" IPR000990:Innexin CG10125 11-Aug-17 DroID_v2017_08 "Drer\panx1b, Drer\panx3" - "Cele\inx-5, Cele\inx-12, Cele\inx-3, Cele\inx-13, Cele\inx-2, Cele\inx-17, Cele\che-7, Cele\inx-18, Cele\inx-7, Cele\inx-16, Cele\inx-19, Cele\inx-9, Cele\inx-6, Cele\inx-20, Cele\unc-9, Cele\inx-10, Cele\unc-7, Cele\inx-14, Cele\inx-15, Cele\inx-11, Cele\inx-22, Cele\inx-21, Cele\inx-1, Cele\inx-8, Cele\eat-5" - - - " embryonic stage | stage 13 , embryonic stage | blastoderm , adult stage , adult stage | male " " germline cell

, pole cell

, spermatogonium

" " adult stage | female && oogenesis stage | stage S6-7 , larval stage | third instar , adult stage " " egg chamber

, spermatogonium

, germarium

, ovariole | stage 8-9

, primary spermatocyte cyst

" "lethal,recessive,viable,male sterile,female sterile" "ovary,female germline cell,testis,male germline stem cell,primary gonial cell,spermatogonium,hub cell,supernumerary,cyst cell,egg chamber,female germline stem cell,germ cell & germarium,cystoblast,cystocyte,nurse cell fusome" FBgn0030725 CG8958 - http://flybase.org/reports/FBgn0030725 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8958 "IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR014710:RmlC-like jelly roll fold" CG8958 11-Aug-17 DroID_v2017_08 - - "Cele\egl-4, Cele\pkg-2" - Mmus\Cnbd2 Hsap\CNBD2 viable FBgn0053463 CG33463 - http://flybase.org/reports/FBgn0053463 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33463 IPR010512:Protein of unknown function DUF1091 CG33463 11-Aug-17 DroID_v2017_08 - - - - - - DRSC22915 K 0.106040764 -0.202488313 0.613337695 -0.304039787 -1.15425978 1.570047847 FBgn0261805 CG42751 - http://flybase.org/reports/FBgn0261805 protein_coding_gene - - - CG42751 - CG42751 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0267050 CG45494 - http://flybase.org/reports/FBgn0267050 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45494 - CG45494 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038657 CG14293 - http://flybase.org/reports/FBgn0038657 protein_coding_gene - - - CG14293 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0019953 NucU NucU http://flybase.org/reports/FBgn0019953 - gene deoxyribonuclease activity ; GO:0004536 | inferred from direct assay DNA catabolic process ; GO:0006308 | inferred from direct assay - NucU - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0033247 Nup44A Nucleoporin at 44A http://flybase.org/reports/FBgn0033247 protein_coding_gene - regulation of TORC1 signaling ; GO:1903432 | inferred from mutant phenotype negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype regulation of meiotic cell cycle ; GO:0051445 | inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | NOT inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000003068 lysosome ; GO:0005764 | inferred from direct assay GATOR2 complex ; GO:0061700 | traceable author statement protein complex ; GO:0043234 | inferred from physical interaction with mio nuclear envelope ; GO:0005635 | inferred from direct assay Seh1-associated complex ; GO:0035859 | inferred from direct assay autolysosome ; GO:0044754 | inferred from direct assay "nup44A, CG8722, Nup44A, Nup44A/Seh1, seh1, FBgn 33247, Seh1" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR020472:G-protein beta WD-40 repeat" CG8722 11-Aug-17 DroID_v2017_08 "Drer\pxk, Drer\seh1l" Scer\SEH1 Cele\npp-18 "Xtro\seh1l, Xtro\pxk" "Mmus\Seh1l, Mmus\Pxk" "Hsap\SEH1L, Hsap\PXK" "viable,recessive,female semi-sterile,visible,partially lethal - majority die,some die during pupal stage" "egg chamber,germarium,oocyte,centriole,microtubule,eye,trichogen cell,mesothoracic tergum" DRSC07248 I -0.27118393 1.546647239 0.146521244 0.36702857 -0.022626356 -0.35121396 FBgn0061200 Nup153 Nucleoporin 153kD http://flybase.org/reports/FBgn0061200 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 chromatin DNA binding ; GO:0031490 | inferred from direct assay nucleocytoplasmic transporter activity ; GO:0005487 | inferred from mutant phenotype nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 structural constituent of nuclear pore ; GO:0017056 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | inferred from mutant phenotype chromatin organization involved in regulation of transcription ; GO:0034401 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from mutant phenotype nuclear pore organization ; GO:0006999 | inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype protein import into nucleus ; GO:0006606 | inferred from mutant phenotype RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 nuclear euchromatin ; GO:0005719 | inferred from direct assay nuclear periphery ; GO:0034399 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay nuclear pore central transport channel ; GO:0044613 | inferred from mutant phenotype mitotic spindle ; GO:0072686 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG4453, dNup153, Nup153, NUP153, nup153, dmNup153, Nup 153" "IPR001876:Zinc finger, RanBP2-type, IPR026054:Nuclear pore complex protein" CG4453 11-Aug-17 DroID_v2017_08 "Drer\pom121, Drer\nup153" "Scer\NUP1, Scer\NUP2, Scer\NSP1" Cele\npp-7 Xtro\nup153 "Mmus\Pom121l2, Mmus\Nup153, Mmus\Pom121" "Hsap\POM121L12, Hsap\POM121L2, Hsap\POM121, Hsap\NPAP1, Hsap\NUP153, Hsap\POM121C" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell,male germline cell,cyst progenitor cell,germline stem cell" DRSC19904 IE -1.964488456 -2.705440451 6.118500721 -5.615081464 0.116589008 -0.007277346 FBgn0267592 CCY Coiled-Coils Y http://flybase.org/reports/FBgn0267592 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CCY, Ccy, CG45930, bs20e03.y1, NEST:bs20e03, ccy, CG40968, CG42620, CG40948" - CG45930 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262510 CR43080 - http://flybase.org/reports/FBgn0262510 pseudogene_attribute - - - "CG43080, CR43080, CG4164" - CR43080 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261848 CG42780 - http://flybase.org/reports/FBgn0261848 protein_coding_gene - - - CG42780 "IPR034763:Venom allergen 3, insect, IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG42780 11-Aug-17 DroID_v2017_08 "Drer\pi15b, Drer\pi15a, Drer\glipr1b, Drer\crispld1a, Drer\glipr2l, Drer\crispld2, Drer\crispld1b, Drer\r3hdml, Drer\LOC100536500, Drer\glipr2" "Scer\PRY1, Scer\PRY2, Scer\PRY3" "Cele\scl-27, Cele\scl-23" "Xtro\crisp1, Xtro\r3hdml, Xtro\crispld2, Xtro\crisp2, Xtro\MGC108118, Xtro\crisp3, Xtro\glipr2" "Mmus\Crispld2, Mmus\Pi16, Mmus\Glipr2, Mmus\Crisp2, Mmus\Clec18a, Mmus\Crisp4, Mmus\Crisp1, Mmus\Glipr1l2, Mmus\Crisp3, Mmus\Glipr1l1, Mmus\R3hdml, Mmus\Glipr1, Mmus\Pi15, Mmus\Crispld1" "Hsap\CRISPLD2, Hsap\CRISPLD1, Hsap\PI15, Hsap\GLIPR1, Hsap\CRISP2, Hsap\CRISP1, Hsap\PI16, Hsap\CLEC18A, Hsap\GLIPR2, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\R3HDML, Hsap\CLEC18B" FBgn0265761 CR44568 - http://flybase.org/reports/FBgn0265761 non_protein_coding_gene - - - "CR44568, lincRNA.982" - CR44568 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030065 CG12075 - http://flybase.org/reports/FBgn0030065 protein_coding_gene - - - CG12075 IPR011993:PH domain-like CG12075 11-Aug-17 DroID_v2017_08 - - Cele\M88.4 - - - "viable,fertile" FBgn0014243 l(2)32Ad lethal (2) 32Ad http://flybase.org/reports/FBgn0014243 - gene - - - l(2)32Ad - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013539 l(2)ry50 lethal (2) ry50 http://flybase.org/reports/FBgn0013539 - gene - - - "l(2)50, l(2)ry50" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265828 CR44617 - http://flybase.org/reports/FBgn0265828 non_protein_coding_gene - - - CR44617 - CR44617 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0086305 scnt scanty http://flybase.org/reports/FBgn0086305 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - scnt - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0039523 CG12885 - http://flybase.org/reports/FBgn0039523 protein_coding_gene - - - CG12885 IPR015943:WD40/YVTN repeat-like-containing domain CG12885 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0036419 CG13482 - http://flybase.org/reports/FBgn0036419 protein_coding_gene - - - CG13482 - CG13482 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0010359 gammaTry gammaTrypsin http://flybase.org/reports/FBgn0010359 "FBgn0050028, FBgn0061399" protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues - - "gamma-Try, CG30028, SPH180, DmGammaTry, gamma, BcDNA:RE40325, gammaTry, endo-I, Try" - CG30028 11-Aug-17 DroID_v2017_08 "Drer\prss60.3, Drer\try, Drer\zgc:92590, Drer\zgc:112038, Drer\zgc:153968, Drer\tmprss4b, Drer\si:dkeyp-93a5.2, Drer\prss60.2, Drer\zgc:123295, Drer\prss60.1, Drer\zgc:163079" - Cele\try-1 - "Mmus\Try10, Mmus\2210010C04Rik, Mmus\Prss2, Mmus\Prss3, Mmus\Prss1, Mmus\Prss53, Mmus\Gm5771, Mmus\Try4, Mmus\Prss36, Mmus\Prss34, Mmus\Gm10334" "Hsap\PRSS36, Hsap\PRSS53, Hsap\PRSS3, Hsap\PRSS1" " larval stage | third instar , adult stage " larval digestive system | restricted

FBgn0266326 CR44991 - http://flybase.org/reports/FBgn0266326 non_protein_coding_gene - - - CR44991 - CR44991 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031191 Cp110 Centriolar coiled coil protein 110kDa http://flybase.org/reports/FBgn0031191 protein_coding_gene - regulation of cytokinesis ; GO:0032465 | inferred from electronic annotation with InterPro:IPR033207 centriole replication ; GO:0007099 | inferred from mutant phenotype negative regulation of centriole elongation ; GO:1903723 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay "CG32501, Cp110, DCP110, CG14617, CP110" "IPR000048:IQ motif, EF-hand binding site, IPR033207:Centriolar coiled-coil protein of 110 kDa" CG14617 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-100l22.3, Drer\LOC101882181" - - - Mmus\Ccp110 Hsap\CCP110 "viable,lethal - all die before end of pupal stage,fertile" "axoneme,spermatocyte,centriole,wing disc" FBgn0002134 l(2)K215 lethal (2) K215 http://flybase.org/reports/FBgn0002134 - gene - - - l(2)K215 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0051700 CR31700 - http://flybase.org/reports/FBgn0051700 pseudogene_attribute - - - "CR31700, CG31700" - CR31700 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020907 Scp2 Sarcoplasmic calcium-binding protein 2 http://flybase.org/reports/FBgn0020907 FBgn0025677 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 GTPase activity ; GO:0003924 | inferred from direct assay - - "dSCP2, cex, CE, JHDK, SCP2, Dcabp-A.2, Cex, CG14904, Scp2" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG14904 11-Aug-17 DroID_v2017_08 Drer\sdf4 - "Cele\cex-1, Cele\cex-2" - Mmus\Sdf4 "Hsap\CETN3, Hsap\SDF4" adult stage neuron &&of adult brain | restricted

viable FBgn0016705 Reg-10 Rhythmically expressed gene 10 http://flybase.org/reports/FBgn0016705 - gene - - - "Dreg-10, Reg-10" - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult head

FBgn0019790 l(1)13 lethal (1) 13 http://flybase.org/reports/FBgn0019790 - gene - - - l(1)13 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060711 l(3)S070204 lethal (3) S070204 http://flybase.org/reports/FBgn0060711 gene - - - "0702/04, l(3)S070204" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000399 cvl-5 crossveinless-like 5 http://flybase.org/reports/FBgn0000399 - gene - - - "cvl, cvl-5" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" crossvein FBgn0003550 Suc Sucrase http://flybase.org/reports/FBgn0003550 - gene - - - "SUCR, Sucr, Suc" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0004647 N Notch http://flybase.org/reports/FBgn0004647 "FBgn0000311, FBgn0002916, FBgn0017616, FBgn0024967, FBgn0026804" protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 transmembrane signaling receptor activity ; GO:0004888 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Su(H) receptor activity ; GO:0004872 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with dx protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI3 protein binding ; GO:0005515 | inferred from physical interaction with Dl inferred from physical interaction with Ser inferred from physical interaction with wry protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y0H4 protein binding ; GO:0005515 | inferred from physical interaction with shg transmembrane signaling receptor activity ; GO:0004888 | non-traceable author statement chromatin binding ; GO:0003682 | inferred from direct assay" "epithelial cell proliferation involved in Malpighian tubule morphogenesis=0061331; crystal cell differentiation=0042689; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules=0007157; R7 cell differentiation=0045466; glial cell fate determination=0007403; wing margin morphogenesis=0008587; ovarian follicle cell migration=0007297; dorsal/ventral lineage restriction, imaginal disc=0007451; germ-line stem cell population maintenance=0030718; lamellocyte differentiation=0035171; cell adhesion=0007155; neuroblast fate determination=0007400; dorsal appendage formation=0046843; lateral inhibition=0046331; negative .. lamellocyte differentiation=0035204; asymmetric cell division=0008356; wing morphogenesis=0007476; crystal cell differentiation=0042688; formation of a compartment boundary=0060288; .. cell differentiation=0045595; anterior/posterior pattern specification=0009952; chaeta morphogenesis=0008407; long-term memory=0007616; ovarian follicle cell=0030707; ovarian follicle cell stalk formation=0030713; egg chamber formation=0007293; R8 cell spacing in compound eye=0045468; border follicle cell migration=0007298; compound eye=0048749; intestinal stem cell homeostasis=0036335; oocyte anterior/posterior axis specification=0007314; chaeta=0022416; JNK cascade=0046329; actin filament organization=0007015; defense response to insect=0002213; Notch signaling pathway=0045747; leg segmentation=0036011; wing disc proximal/distal pattern formation=0007473; ovarian follicle cell stalk formation=0030713; lymph gland=0048542; R1/R6 cell differentiation=0048052; muscle cell fate determination=0007521; gene expression=0010629; cardioblast cell fate specification=0042686; compound eye morphogenesis=0016330; male genitalia morphogenesis=0048803; morphogenesis of follicular epithelium=0016333; larval lymph gland hemopoiesis=0035167; compound eye morphogenesis=0016330; imaginal disc-derived wing morphogenesis=0007476; photoreceptor=0045316; retinal cell programmed cell death=0046666; compound eye=0048749; open tracheal system=0007424; embryonic crystal cell differentiation=0035165; cone cell fate commitment=0042676; open tracheal system=0035155; adult lifespan=0008340; germarium-derived female germ-line cyst encapsulation=0030708; axon guidance=0007411; neurogenesis=0050767; R7 cell differentiation=0045466; ovarian follicle cell=0030707; female germ-line stem cell population maintenance=0036099; fusion cell fate specification=0035157; wing disc dorsal/ventral pattern formation=0048190; motor neuron axon guidance=0008045; cell-cell adhesion mediated by cadherin=2000048; glucose metabolic process=0010906; cell fate specification=0001708; glial cell differentiation=0010001; long-term memory=0007616; dorsal closure=0007391; transcription, DNA-templated=0045893; lymph gland crystal cell differentiation=0035170; imaginal disc-derived leg joint morphogenesis=0016348; imaginal disc-derived wing hair orientation=0001737; egg chamber formation=0030720; ommatidial planar polarity=0042067; R8 cell fate commitment=0007460; lateral inhibition=0046331; mitotic cell cycle=0007346; foregut morphogenesis=0007440; G1/S transition of mitotic cell cycle=1900087; growth=0040008; cell fate specification=0001708; R3/R4 cell fate commitment=0007464; hemocyte proliferation=0035172; I-kappaB phosphorylation=0007252; hemopoiesis=0035162; retinal cell programmed cell death=0046667; filopodium assembly=0051489; R8 cell=0045463; establishment of ommatidial planar polarity=0042067; glial cell migration=0008347; germ-line stem-cell niche homeostasis=0060250; R8 cell differentiation=0045465; sensory organ=0007423; wing vein specification=0007474; cell proliferation=0008284; open tracheal system=0035153; glycolytic process=0006110; crystal cell differentiation=0042691; Malpighian tubule tip cell differentiation=0061382" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010660, InterPro:IPR011656 cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay endosome ; GO:0005768 | inferred from direct assay subapical complex ; GO:0035003 | inferred from direct assay endocytic vesicle ; GO:0030139 | inferred from direct assay intracellular ; GO:0005622 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay late endosome ; GO:0005770 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement integral component of membrane ; GO:0016021 | traceable author statement protein complex ; GO:0043234 | inferred from physical interaction with Su(H) lysosome ; GO:0005764 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay" "N, Notch, notch, CG3936, EG:163A10.2, CT13012, dNotch, swb, shd, nd, Co, Chp, Ax, spl, fa, 1.1, clone 1.12, n[fah], co, 16-55, 16-178, l(1)N, l(1)Ax, l(1)3Cb, anon-EST:Liang-1.12, EG:140G11.1, NICD, NECD, RICN" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR000800:Notch domain, IPR001881:EGF-like calcium-binding domain, IPR002110:Ankyrin repeat, IPR008297:Notch, IPR010660:Notch, NOD domain, IPR011656:Notch, NODP domain, IPR013032:EGF-like, conserved site, IPR020683:Ankyrin repeat-containing domain, IPR024600:Domain of unknown function DUF3454, notch, IPR009030:Growth factor receptor cysteine-rich domain" CG3936 11-Aug-17 DroID_v2017_08 "Drer\notch1a, Drer\si:ch73-281k2.5, Drer\crb1, Drer\notch1b, Drer\notch3, Drer\fbn2b, Drer\LOC562634, Drer\notch2, Drer\crb2a, Drer\fbn2a, Drer\crb2b" - "Cele\crb-1, Cele\clec-78, Cele\lin-12, Cele\glp-1, Cele\Y64G10A.7, Cele\mup-4, Cele\fbn-1, Cele\mua-3" "Xtro\notch1, Xtro\agrn, Xtro\notch3, Xtro\notch2" "Mmus\Notch4, Mmus\Fbn1, Mmus\Fbn2, Mmus\Notch3, Mmus\Crb2, Mmus\Crb1, Mmus\Notch1, Mmus\Notch2" "Hsap\CRB1, Hsap\FBN2, Hsap\CRB2, Hsap\EYS, Hsap\NOTCH4, Hsap\NOTCH2, Hsap\FBN3, Hsap\FBN1, Hsap\NOTCH3, Hsap\NOTCH1" " embryonic stage | stage 17 , embryonic stage | stage 15 , embryonic stage , pupal stage , embryonic stage | stage 14 , embryonic stage | stage 1-16 , embryonic stage -- adult stage , adult stage , embryonic stage | stage 13 , embryonic stage | stage 10 , larval stage " " foregut

, ventral nerve cord

, ventral nerve cord primordium

, embryonic epidermis

, visual primordium

, procephalic neurogenic region

, embryonic central nervous system | resricted

" " adult stage && oogenesis stage , pupal stage , larval stage | third instar " " germarium region 3

, oocyte

, leg & joint | distal

, germarium region 2

, nurse cell

, germarium region 1

, ventral thoracic disc

, follicle cell

" "visible,dominant,neuroanatomy defective,hyperplasia,heat sensitive,lethal,recessive,neurogenic phenotype,somatic clone,decreased cell number,wild-type,viable,semi-lethal,cold sensitive,reduced,partially,fertile,planar polarity defective,memory defective,increased cell death,size defective,female sterile,immune response defective,decreased cell death,cell shape defective,courtship behavior defective,temperature conditional,mitotic cell cycle defective,poor,germline clone,maternal effect,male,female,female limited,sterile,female fertile,homeotic,chemosensitive behavior defective,increased cell number,cell non-autonomous" "wing blade-vein-margin,embryo/larva nervous system-brain,lamina anlage,medulla anlage,larval outer optic anlage,abdominal ventral multidendritic neuron,leg,prothoracic tibial- mesothoracic apical bristle,external sensory organ,vMP2&RP2&dMP2& pioneer neuron,neuroblast,embryo/larva CNS&PNS,wing disc,ectoderm,ventral nerve cord,epidermis,embryo/larva foregut-hindgut-tracheal system-salivary gland,adult thoracic sensillum,Malpighian tubule & primordium,tracheal branch primordium,follicle cell,centripetally migrating-polar-interfollicle cell,mitotic cell cycle,ventral thoracic disc,embryo/larva somatic muscle,joint,leg sensillum,tibia,femur,egg chamber,embryo epidermis & myoblast,macrochaeta,sensory mother cell,pCC&aCC&RP2sib&U&eo&multidendritic neuron,dorsal-ventral double row,segment border muscle,wing sensillum,embryo/larva dorsal vessel,support cell of the dorsal bipolar dendritic cell,scolopidial ligament cell,proventriculus inner/intermediate/outer layer primordium,embryo proventriculus,keyhole structure,midline glial cell,procrystal cell,embryo/1st instar larva cuticle,germline cyst,oocyte,anterior-posterior scutellar bristle,adult/embryo/larva midgut,germarium cap cell,ventral nerve cord primordium,chaeta,fascicle,eye,ommatidium,optic lobe,cortex of lamina,medulla/lamina neuropil,primary/secondary/tertiary pigment cell,lens, CNS,embryo/larva pericardial cell & stomatogastric nervous system,microchaeta,medulla,ocellar bristle,photoreceptor cell,ganglion mother cell,mushroom body,tormogen cell,medial triple row,dorsal triple row,sensillum campaniformium of anterior crossvein,antennal sense organ,trichome of the posterior wing margin,basal stalk,female germline stem cell,S2 cell-line, extended germ band embryo,abdominal dorsal acute muscle,pericardial cell,dorsal-mesothoracic-metathoracic acute muscle 1,dorsocentral-mesothoracic tarsal bristle,mesothoracic leg sensillum,mesothoracic metatarsus,supraalar-presutural-scutellar-sternopleural-orbital bristle,vibrissae,photoreceptor,head,twin sensillum of margin,wing nerve,antenna,mechanosensory sensory organ,subperineurial glial cell,ovary,pigment cell,border follicle cell,embryo/larva dorsal branch,nurse follicle cell,lymph gland primordium,cardioblast,embryo/larva lymph gland-lateral trunk-dorsal trunk,glial cell,chorion,dorsal appendage,nurse cell,oocyte associated follicle cell,trichogen cell,thecogen cell,longitudinal connective,eye-antennal disc,sensillum trichodeum-basiconicum-coeloconicum of antennal segment,sacculus,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,ovariole,dorsal pouch,adult head,oocyte nucleus,egg,intersegmental nerve,ventral midline,neuromere,dorsal multidendritic neuron ddaD&ddaE,crystal cell,metatarsus,hub cell,vMP2 tract,filopodium,ocellus,posterior notopleural-anterior-posterior supraalar bristle,posterior postalar-metathoracic bristle,costal vein,glioblast,posterior wing margin,embryo/larva corpus cardiacum,corpus cardiacum primordium,thorax,cuticle,salivary gland,postvertical bristle,muscle founder cell,sense organ,submarginal cell,antennal disc,morphogenetic furrow,adult thorax,NMJ bouton,embryo/larva NMJ,dorsal-ventral compartment boundary of the wing,Usib &EL & sensory neuron,embryo heart cardioblast,embryo/larva trachea,myoblast,embryo large intestine,C1 chordotonal organ precursor cell,oenocyte primordium,mesothoracic-metathoracic-prothoracic dorsal oblique muscle,transverse & acute muscle,visceral& somatic mesoderm,subesophageal ganglion neuron,tarsal segment,external sensory organ precursor cell,ommatidial precursor cluster,lobula,bract,follicle stem cell,embryo/larva muscle system,abdominal-mesothoracic-metathoracic-prothoracic intersegmental nerve,adult midgut precursor cell|late,myoblast,segmental nerve,adult muscle precursor cell,anterior crossvein,socket,male genitalia,cone cell,retina|adult stage,enterocyte of posterior adult midgut epithelium,intestinal stem cell,enteroendocrine cell" FBgn0000157 Dll Distal-less http://flybase.org/reports/FBgn0000157 "FBgn0010474, FBgn0026807, FBgn0063133" protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "imaginal disc-derived male genitalia development ; GO:0007485 | non-traceable author statement leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype olfactory nerve development ; GO:0021553 | inferred from mutant phenotype antennal development ; GO:0007469 | traceable author statement determination of ventral identity ; GO:0048264 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from expression pattern positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype proximal/distal pattern formation, imaginal disc ; GO:0007449 | traceable author statement proboscis development ; GO:0048728 | inferred from mutant phenotype antennal development ; GO:0007469 | inferred from mutant phenotype specification of animal organ identity ; GO:0010092 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype imaginal disc-derived appendage morphogenesis ; GO:0035114 | inferred from mutant phenotype analia development ; GO:0007487 | traceable author statement imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype genital disc development ; GO:0035215 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "Dll, dll, l(2)01092, 2.7, Ba, En(Arp), l(2)387, E(Arp), CG3629, Art, BcDNA:LP01770, DLL, Distal-less" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG3629 11-Aug-17 DroID_v2017_08 "Drer\dlx6a, Drer\hoxb13a, Drer\hoxd13a, Drer\dlx5a, Drer\hoxc13a, Drer\dlx4a, Drer\dlx2a, Drer\dlx1a, Drer\dlx2b, Drer\dlx4b, Drer\six4a, Drer\hoxa13a, Drer\dlx3b" - "Cele\ceh-43, Cele\ceh-9, Cele\pha-2" "Xtro\hoxd10, Xtro\dlx1, Xtro\dlx6, Xtro\dlx5, Xtro\dlx2, Xtro\dlx4, Xtro\dlx3, Xtro\hoxd13" "Mmus\Dlx2, Mmus\Dlx1, Mmus\Dlx4, Mmus\Hoxc13, Mmus\Dlx6, Mmus\Hoxd13, Mmus\Dlx3, Mmus\Dlx5" "Hsap\HOXC13, Hsap\DLX6, Hsap\HOXD13, Hsap\DLX3, Hsap\DLX1, Hsap\DLX4, Hsap\DLX5, Hsap\DLX2" " larval stage | second instar , larval stage | first instar , embryonic stage , larval stage | third instar " embryonic stage | extended germ band " maxillary segment

, dorsal prothoracic disc primordium

, labral segment

, labial disc primordium

, dorsal metathoracic disc primordium

" "visible,dominant,lethal,homeotic,recessive,chemosensitive behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,neuroanatomy defective,somatic clone,lethal - all die before end of P-stage,some die during pharate adult stage,cold sensitive,lethal - all die before end of larval stage,some die during larval stage" "antenna,tarsal segment,distal,third segment of antenna,leg,ectopic,mushroom body pedunculus | embryonic stage 12,Kenyon cell | embryonic stage 12,mushroom body vertical lobe | embryonic stage 12,mushroom body medial lobe | embryonic stage 12,unguis,prothoracic metatarsus,sex comb,hypostomal sclerite,embryonic/larval labial organ,antennal sense organ,terminal organ,Keilin's organ,femur,tibia,arista,metatarsus,proximal,dorsal organ,mushroom body pedunculus,Kenyon cell,mushroom body vertical lobe,mushroom body medial lobe,somatic clone,wing margin bristle,cell autonomous,adult cuticle,anal plate,ventral thoracic disc,trochanter,macrochaeta & leg | somatic clone,mesothoracic femoral bract,mesothoracic tibial bract,metathoracic femoral bract,metathoracic tibial bract,prothoracic femoral bract,prothoracic tibial bract,second segment of antenna,dorsal triple row,medial triple row,ventral triple row,dorsal double row,ventral double row,wing vein,cell non-autonomous,wing,posterior compartment,anterior compartment,wing & macrochaeta | somatic clone,male,epiproct,female,distiproboscis,tibia & macrochaeta,macrochaeta,antennal segment 2 & macrochaeta,femur & macrochaeta,adult hindgut,female gonopod,cold sensitive,peripheral nervous system,adult head,female genitalia,male genitalia,analia,precursor,eye,haltere,head,wing margin,joint,bract" DRSC04610 I -1.913149107 0.038014634 -0.577701054 0.271201117 0.538541364 -1.361151523 FBgn0037678 CG16749 - http://flybase.org/reports/FBgn0037678 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP91, CG16749" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG16749 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001088, Drer\prss59.1, Drer\zgc:171509, Drer\LOC103908930, Drer\prss59.2, Drer\LOC560023" - - Xtro\prss1.2 "Mmus\Klk1b3, Mmus\Klk14, Mmus\Prss36, Mmus\Klk1b24, Mmus\Klk8, Mmus\Klk1b22, Mmus\Klk1b27, Mmus\Klk1b21, Mmus\Klk13, Mmus\Klk1b26, Mmus\Klk4, Mmus\Klk11, Mmus\Klk1b11, Mmus\Klk12, Mmus\Klk6, Mmus\Klk1b8, Mmus\Klk1b5, Mmus\Habp2, Mmus\Try5, Mmus\Prss8, Mmus\Klk15, Mmus\Klk7, Mmus\Klk1b16, Mmus\Klk1b1, Mmus\Klk9, Mmus\Klk5, Mmus\Mcpt8, Mmus\Klk1b4, Mmus\Egfbp2, Mmus\Prss53, Mmus\Klk1, Mmus\Klk1b9, Mmus\Klk10" "Hsap\KLK14, Hsap\KLK9, Hsap\KLK11, Hsap\CTSG, Hsap\KLK6, Hsap\KLK2, Hsap\KLK8, Hsap\KLK1, Hsap\KLK4, Hsap\KLK15, Hsap\KLK3, Hsap\CFD, Hsap\PRSS53, Hsap\KLK7, Hsap\KLK10, Hsap\KLK5, Hsap\PRSS36, Hsap\KLK13, Hsap\KLK12" viable FBgn0267445 Su(Ste):CR45795 Supressor of Stellate:CR45795 http://flybase.org/reports/FBgn0267445 non_protein_coding_gene - - - "Su(Ste):CR45795, CR45795" - CR45795 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039832 CG15563 - http://flybase.org/reports/FBgn0039832 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15563 - CG15563 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC15101 EK 0.311745021 -0.64290603 -2.435719221 0.158246264 2.426189718 0.454117504 FBgn0067099 H66 H66 http://flybase.org/reports/FBgn0067099 gene - - - H66 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "chaeta,trichogen cell" FBgn0052185 edin elevated during infection http://flybase.org/reports/FBgn0052185 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to Gram-negative bacterium ; GO:0050829 | inferred from expression pattern humoral immune response ; GO:0006959 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG32185, edin, Edin" - CG32185 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,short lived,immune response defective,conditional,viable,visible" trichogen cell DRSC09488 E 0.922479154 0.499418105 1.652986544 0.985368951 -1.086590042 0.494352404 FBgn0039114 Lsd-1 Lipid storage droplet-1 http://flybase.org/reports/FBgn0039114 protein_coding_gene - positive regulation of triglyceride catabolic process ; GO:0010898 | inferred from direct assay lipid storage ; GO:0019915 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype protein localization to lipid particle ; GO:1990044 | inferred from mutant phenotype lipid transport ; GO:0006869 | inferred from expression pattern regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype triglyceride mobilization ; GO:0006642 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay lipid particle ; GO:0005811 | colocalizes_with inferred from direct assay protein-lipid complex ; GO:0032994 | inferred from direct assay "LSD-1, LSDP1, Lsdp1, CG10374, Lsd-1, Lsd1, plin1, lsd1, PLIN1, DmPLIN1" IPR004279:Perilipin CG10374 11-Aug-17 DroID_v2017_08 "Drer\zgc:77486, Drer\si:rp71-61h23.4, Drer\plin2, Drer\zgc:162150" - - "Xtro\plin1, Xtro\plin2, Xtro\plin3" "Mmus\Plin1, Mmus\Plin5, Mmus\Plin3, Mmus\Plin2, Mmus\Plin4" "Hsap\PLIN1, Hsap\PLIN5, Hsap\PLIN2, Hsap\PLIN3, Hsap\PLIN4" "starvation stress response defective,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable,stress response defective,large body" "embryonic/larval fat body,lipid particle,ganglion mother cell,mesothoracic tergum,lipid particlefat" FBgn0019681 mor(1)10 mortality gene (1)10 http://flybase.org/reports/FBgn0019681 - gene - - - mor(1)10 - - 11-Aug-17 DroID_v2017_08 - - - - - - short lived FBgn0038510 CG14331 - http://flybase.org/reports/FBgn0038510 protein_coding_gene - - - CG14331 - CG14331 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035238 CG12104 - http://flybase.org/reports/FBgn0035238 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12104 IPR009071:High mobility group box domain CG12104 11-Aug-17 DroID_v2017_08 "Drer\ubtf, Drer\hmgb1a, Drer\hmg20b, Drer\tox4a, Drer\hmgb1b, Drer\ubtfl, Drer\tox, Drer\tox2, Drer\hmgb2b, Drer\tox4b, Drer\tox3, Drer\hmgb3a, Drer\hmgb2a, Drer\hmg20a, Drer\hmgb3b, Drer\tfam" "Scer\NHP6A, Scer\HMO1, Scer\NHP10, Scer\IXR1, Scer\ABF2, Scer\POB3, Scer\NHP6B" Cele\hmg-6 "Xtro\hmgb3, Xtro\hmg20a, Xtro\hmg20b, Xtro\hmgb2, Xtro\tfam, Xtro\tox3, Xtro\hmgb1, Xtro\tox4, Xtro\tox, Xtro\tox2, Xtro\ubtf" "Mmus\Tfam, Mmus\Tox, Mmus\Ubtf, Mmus\Sp100, Mmus\Hmgb1, Mmus\Ubtfl1, Mmus\Tox3, Mmus\Hmgb3, Mmus\Hmg20b, Mmus\Hmgb2, Mmus\Hmgb4, Mmus\Tox2, Mmus\Hmg20a, Mmus\Tox4" "Hsap\TOX3, Hsap\UBTF, Hsap\TOX, Hsap\HMGB3, Hsap\TOX4, Hsap\TFAM, Hsap\HMGB4, Hsap\HMGB2, Hsap\HMGB1, Hsap\HMG20B, Hsap\TOX2, Hsap\HMG20A" viable FBgn0058081 CG40081 - http://flybase.org/reports/FBgn0058081 protein_coding_gene - - - CG40081 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0025820 JTBR JTBR http://flybase.org/reports/FBgn0025820 "FBgn0025210, FBgn0035275, FBgn0063663" protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008657 "CG1935, dJTBR, dJTB-like, anon-EST:fe2G4, BcDNA:RH07980, JTBR" IPR008657:Jumping translocation breakpoint CG1935 11-Aug-17 DroID_v2017_08 Drer\jtb - Cele\jtr-1 - Mmus\Jtb Hsap\JTB FBgn0067633 70 70 http://flybase.org/reports/FBgn0067633 gene - - - 70 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0067743 l(1)G0284 lethal (1) G0284 http://flybase.org/reports/FBgn0067743 gene - - - l(1)G0284 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0045980 niki nimA-like kinase http://flybase.org/reports/FBgn0045980 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with Nek2" protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with Nek2 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype cilium ; GO:0005929 | inferred from sequence or structural similarity with HGNC:13387 "CG10951, Niki, NEK1, niki" "IPR000408:Regulator of chromosome condensation, RCC1, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG10951 11-Aug-17 DroID_v2017_08 "Drer\nek1, Drer\si:dkey-192d15.2, Drer\LOC101885992, Drer\nek2, Drer\nek7, Drer\LOC100536894, Drer\nek11, Drer\nek12, Drer\si:ch211-285c6.3, Drer\nek4, Drer\nek8, Drer\si:ch211-285c6.2" Scer\KIN3 "Cele\nekl-3, Cele\nekl-2, Cele\nekl-1" "Xtro\nek3, Xtro\nek4, Xtro\nek10, Xtro\nek1, Xtro\nek9, Xtro\nek8, Xtro\stkld1, Xtro\nek5" "Mmus\Nek7, Mmus\Nek6, Mmus\Nek2, Mmus\Nek11, Mmus\Nek1, Mmus\Nek8, Mmus\Nek10, Mmus\Nek3, Mmus\Stkld1, Mmus\Nek5, Mmus\Nek4, Mmus\Nek9" "Hsap\NEK5, Hsap\NEK7, Hsap\NEK10, Hsap\NEK1, Hsap\NEK4, Hsap\NEK11, Hsap\NEK8, Hsap\STKLD1, Hsap\NEK6, Hsap\NEK9, Hsap\MAPK15, Hsap\NEK3, Hsap\NEK2" "lethal,viable" FBgn0016664 Hrp44 Hrp44 http://flybase.org/reports/FBgn0016664 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available nucleolus ; GO:0005730 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "hrp44, Hrp44" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0034639 CG15673 - http://flybase.org/reports/FBgn0034639 protein_coding_gene - - - CG15673 - CG15673 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0037896 ninaG ninaG http://flybase.org/reports/FBgn0037896 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867 oxidoreductase activity ; GO:0016491 | inferred from mutant phenotype" oxidation-reduction process ; GO:0055114 | inferred from mutant phenotype retinoid metabolic process ; GO:0001523 | inferred from mutant phenotype transport ; GO:0006810 | inferred from mutant phenotype visual perception ; GO:0007601 | inferred from mutant phenotype rhodopsin metabolic process ; GO:0046154 | inferred from mutant phenotype - "CG6728, ninaG, NinaG" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR023753:FAD/NAD(P)-binding domain" CG6728 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH "viable,fertile,neurophysiology defective" "rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rough endoplasmic reticulum & eye photoreceptor cell,eye" FBgn0060360 l(3)S140009b lethal (3) S140009b http://flybase.org/reports/FBgn0060360 gene - - - "1400/09, l(3)S140009b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263632 mir-3642 mir-3642 stem loop http://flybase.org/reports/FBgn0263632 miRNA_gene - - - "mir-3642, CR43534" - CR43534 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0264840 CR44048 - http://flybase.org/reports/FBgn0264840 non_protein_coding_gene - - - CR44048 - CR44048 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003160 pts ponte thermosensible http://flybase.org/reports/FBgn0003160 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available pts - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,heat sensitive" FBgn0036804 Sgf11 SAGA associated factor 11kDa http://flybase.org/reports/FBgn0036804 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with not "histone deubiquitination ; GO:0016578 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay histone deubiquitination ; GO:0016578 | inferred from direct assay axon target recognition ; GO:0007412 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype" DUBm complex ; GO:0071819 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Sgf11, CG13379, dSgf11, sgf11" "IPR013246:SAGA complex, Sgf11 subunit" CG13379 11-Aug-17 DroID_v2017_08 "Drer\atxn7l3, Drer\si:dkeyp-118b1.2" Scer\SGF11 - Xtro\atxn7l3 "Mmus\Atxn7l3b, Mmus\Atxn7l3" "Hsap\ATXN7L3, Hsap\ATXN7L3B" "lethal,recessive,neuroanatomy defective,enhancer of variegation,dominant,viable,fertile,body color defective" "axon & photoreceptor cell R2,axon & photoreceptor cell R3,axon & photoreceptor cell R4,axon & photoreceptor cell R5,ventral interface glial cell,dorsal interface glial cell,mesothoracic tergum" FBgn0264867 CR44058 - http://flybase.org/reports/FBgn0264867 non_protein_coding_gene - - - "CR44058, lincRNA.33" - CR44058 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0011766 E2f1 E2F transcription factor 1 http://flybase.org/reports/FBgn0011766 "FBgn0010918, FBgn0011343, FBgn0011351, FBgn0011520, FBgn0011767, FBgn0013944, FBgn0016652" protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR032198 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:3113 inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Dp transcription factor binding ; GO:0008134 | inferred from physical interaction with Rbf protein binding ; GO:0005515 | inferred from physical interaction with l(3)mbt inferred from physical interaction with dom protein binding ; GO:0005515 | inferred from physical interaction with Rbf RNA polymerase II regulatory region DNA binding ; GO:0001012 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | contributes_to inferred from physical interaction with Dp transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from physical interaction with Dp DNA binding ; GO:0003677 | inferred from direct assay" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay eggshell chorion gene amplification ; GO:0007307 | traceable author statement regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | non-traceable author statement DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype inferred from genetic interaction with CycE positive regulation of nurse cell apoptotic process ; GO:0045850 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype muscle tissue development ; GO:0060537 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | traceable author statement regulation of execution phase of apoptosis ; GO:1900117 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay G1/S transition of mitotic cell cycle ; GO:0000082 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | non-traceable author statement" Rb-E2F complex ; GO:0035189 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "dE2F1, E2F, dE2f1, E2f1, dE2F, E2F1, def21, CG6376, e2f1, e2f, de2f1, E2F-1, E(var)3-93E, E(Sev-CycE)3A, drosE2F1, dE2f, E(var)3-95E, DmE2F-1, DRTF1/E2F, Evar(3)164, l(3)rM729, l(3)j3C2, l(3)j3B1, l(3)07172, E(var)93E, E2f, Dp, E2F transcription factor 1" "IPR003316:E2F/DP family, winged-helix DNA-binding domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR015633:E2F Family, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032198:E2F transcription factor, CC-MB domain" CG6376 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-195d17.2, Drer\e2f3, Drer\e2f4, Drer\e2f5, Drer\si:ch211-160f23.5, Drer\e2f1" - "Cele\efl-2, Cele\efl-1" "Xtro\e2f4, Xtro\e2f1, Xtro\e2f3, Xtro\e2f5" "Mmus\E2f6, Mmus\E2f2, Mmus\E2f1, Mmus\E2f4, Mmus\E2f5, Mmus\E2f3" "Hsap\E2F5, Hsap\E2F6, Hsap\E2F4, Hsap\E2F2, Hsap\E2F1, Hsap\E2F3" " embryonic stage , embryonic stage | stage 16 , embryonic stage | stage 7 , embryonic stage | stage >=12 , embryonic stage | stage 13 , embryonic stage | stage 8-11 , embryonic stage | stage 1 , embryonic stage | stage 1-4 , embryonic stage | stage 9-11 , embryonic stage | stage 12 , embryonic stage | stage >=10 , embryonic stage | early " " embryonic central nervous system

, embryonic/larval midgut

, ventral furrow

, embryonic brain

, anterior embryonic/larval midgut

, embryonic/larval foregut

, mesoderm

,

ubiquitous , neuroblast

, embryonic central nervous system | restricted

, posterior embryonic/larval midgut

" "female sterile,visible,increased cell death,heat sensitive,radiation resistant,cell non-autonomous,increased cell number,neuroanatomy defective,homeotic,partially lethal - majority die,lethal,cell death defective,viable,partially,recessive,mitotic cell cycle defective,fertile,decreased cell size,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,enhancer of variegation,melanotic mass phenotype,behavior defective,dominant,decreased cell death,maternal effect,female fertile,male fertile,non-suppressor of variegation,non-enhancer of variegation,some die during pupal stage,increased cell size,somatic clone,suppressor of variegation,wild-type" "eye,heterochromatin & nurse cell, with E2f191,ommatidium,1st posterior cell,wing,wing disc,cell non-autonomous,neuroblast NB6-4 of thorax,ectopic,neuroblast NB6-4 of abdomen,wing vein,wing blade,wing pouch,abdomen,macrochaeta,nurse cell,chorion,follicle cell,ovary,heterochromatin & nurse celle-BS2),nuclear chromosome & nurse celle-BS2),nuclear membrane & nurse celle-BS2),polar body nucleus,oocyte,egg,dorsal appendage,posterior | third instar larval stage,mitotic cell cycle,antenna,interommatidial bristle,heart primordium,anterior midgut primordium,posterior midgut primordium,eye disc posterior to the morphogenetic furrow,posterior compartment,imaginal disc,embryonic/larval optic lobe,eye disc,eye disc & mitotic cell cycle,epidermis,peripheral nervous system,chordotonal organ,heterochromatin & nurse cell, with E2f1hs.PD,neuroblast NB6-4,embryonic thorax & neuron,eye-antennal disc,eye photoreceptor cell,rhabdomere,midgut primordium & S phase,follicle stem cell,somatic clone,trichogen cell,mesothoracic tergum,larval outer optic anlage,photoreceptor cell,central nervous system,neuroblast,larval optic anlage" DRSC16655 IEK -3.069120889 -2.378068942 -2.579935112 -2.670236433 10.0646481 14.85815627 FBgn0030933 CG6470 - http://flybase.org/reports/FBgn0030933 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "anon-WO0140519.137, CG6470" IPR013087:Zinc finger C2H2-type CG6470 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0052783 CG32783 - http://flybase.org/reports/FBgn0052783 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32783 - CG32783 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013678 mt:Cyt-b mitochondrial Cytochrome b http://flybase.org/reports/FBgn0013678 "FBgn0002867, FBgn0025273" protein_coding_gene "electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR005797, InterPro:IPR005798, InterPro:IPR030689 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from electronic annotation with InterPro:IPR030689" "mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from electronic annotation with InterPro:IPR030689 spermatogenesis ; GO:0007283 | inferred from mutant phenotype" respiratory chain complex III ; GO:0045275 | inferred from electronic annotation with InterPro:IPR030689 "CG34090, Cytb, cyt b, Cytob, cytb, Cyt-b, anon-EST:fe1B1, mt:Cyt-b, CytB, Cyt b, CYTB, mt:cyt-b, Cyt B" "IPR005797:Cytochrome b/b6, N-terminal, IPR005798:Cytochrome b/b6, C-terminal, IPR016174:Di-haem cytochrome, transmembrane, IPR030689:Cytochrome b, IPR027387:Cytochrome b/b6-like domain" CG34090 11-Aug-17 DroID_v2017_08 Drer\CYTB "Scer\BI2, Scer\BI4, Scer\BI3, Scer\COB" Cele\CYTB Xtro\CYTB Mmus\CYTB Hsap\CYTB "short lived,maternal effect,male sterile" "testis,maternal effect,spermatid" FBgn0085754 CR40597 - http://flybase.org/reports/FBgn0085754 rRNA_gene - - - CR40597 - CR40597 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0031707 CG14020 - http://flybase.org/reports/FBgn0031707 protein_coding_gene - Golgi organization ; GO:0007030 | inferred from mutant phenotype negative regulation of mitotic cell cycle ; GO:0045930 | inferred from mutant phenotype - CG14020 IPR019306:Transmembrane protein 231 CG14020 11-Aug-17 DroID_v2017_08 "Drer\tmem231, Drer\mrpl16" - Cele\tmem-231 "Xtro\tmem231, Xtro\mrpl16" "Mmus\Mrpl16, Mmus\Tmem231" "Hsap\MRPL16, Hsap\TMEM231" "viable,visible" "chaeta,supernumerary,mesothoracic tergum" FBgn0264439 CR43857 - http://flybase.org/reports/FBgn0264439 non_protein_coding_gene - - - CR43857 - CR43857 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005047 E(var)55 Enhancer of variegation 55 http://flybase.org/reports/FBgn0005047 - gene - - - E(var)55 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002577 m miniature http://flybase.org/reports/FBgn0002577 FBgn0030333 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with dy regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inferred from genetic interaction with dy apical constriction ; GO:0003383 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype cell-matrix adhesion ; GO:0007160 | inferred from mutant phenotype epidermal cell differentiation ; GO:0009913 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from genetic interaction with dyl imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity apical plasma membrane ; GO:0016324 | inferred from direct assay "CG9369, min, m, Min, M" IPR001507:Zona pellucida domain CG9369 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-229d2.5, Drer\zmp:0000001031, Drer\zgc:153932, Drer\si:ch211-103f14.3" - "Cele\F46G11.6, Cele\cut-5, Cele\cutl-6, Cele\cut-1, Cele\cutl-29, Cele\cutl-25, Cele\cutl-22, Cele\cutl-16, Cele\cutl-14, Cele\ram-5, Cele\T01D1.8, Cele\cutl-1, Cele\cutl-2, Cele\cutl-10, Cele\cutl-13, Cele\cutl-8, Cele\cutl-12, Cele\cutl-4, Cele\cutl-20, Cele\dpy-1, Cele\cut-4, Cele\cutl-9, Cele\cutl-28, Cele\cutl-7, Cele\cutl-26, Cele\cutl-19, Cele\cutl-3, Cele\cutl-5, Cele\cutl-11, Cele\cut-3, Cele\cut-6, Cele\cutl-24, Cele\cutl-15" "Xtro\MGC89178, Xtro\thdl18, Xtro\thdl17" - - "visible,viable,recessive,semidominant,fertile,female sterile,dominant,male fertile,male sterile,body color defective" "wing,denticle,macrochaeta" FBgn0022811 E(faf)E337 Enhancer of faf E337 http://flybase.org/reports/FBgn0022811 - gene - - - E(faf)E337 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" eye FBgn0001762 l(1)M19 lethal (1) M19 http://flybase.org/reports/FBgn0001762 - gene - - - l(1)M19 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0040169 l(1)G0362 lethal (1) G0362 http://flybase.org/reports/FBgn0040169 gene - - - l(1)G0362 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003082 phr photorepair http://flybase.org/reports/FBgn0003082 "FBgn0011299, FBgn0014003" protein_coding_gene deoxyribodipyrimidine photo-lyase activity ; GO:0003904 | inferred from biological aspect of ancestor with PANTHER:PTN000025285 photoreactive repair ; GO:0000719 | inferred from biological aspect of ancestor with PANTHER:PTN000025285 - "Dm CPD, C2PHR, anonOV1, anon-OV1, Phl, CG11205, phr, CG11205-PA" "IPR005101:Cryptochrome/DNA photolyase, FAD-binding domain, IPR006050:DNA photolyase, N-terminal, IPR008148:DNA photolyase class 2, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR032673:DNA photolyase class 2, conserved site" CG11205 11-Aug-17 DroID_v2017_08 "Drer\cry4, Drer\si:ch1073-390k14.1, Drer\cry1ab, Drer\cry-dash, Drer\cry5, Drer\zgc:66475, Drer\cry1aa, Drer\cry1ba, Drer\cry1bb" Scer\PHR1 - "Xtro\cry4, Xtro\cry1, Xtro\cry2, Xtro\LOC101733551" "Mmus\Cry1, Mmus\Cry2" "Hsap\CRY2, Hsap\CRY1" "DNA repair defective,viable" FBgn0015768 Mst317 Male-specific transcript 317 http://flybase.org/reports/FBgn0015768 - gene - - - Mst317 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0046301 CG7148 - http://flybase.org/reports/FBgn0046301 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "BEST:GH10766, CG7148, FBXL12" "IPR032675:Leucine-rich repeat domain, L domain-like" CG7148 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0051742 Prosbeta5R2 Proteasome beta5 subunit-related 2 http://flybase.org/reports/FBgn0051742 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | inferred from sequence or structural similarity with SGD:S000006307" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000006307 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype "proteasome core complex, beta-subunit complex ; GO:0019774 | inferred from sequence or structural similarity with SGD:S000006307" "CG31742, anon-AE003657.1, 31742, Prosbeta5R2, beta5R2" "IPR000243:Peptidase T1A, proteasome beta-subunit, IPR001353:Proteasome, subunit alpha/beta, IPR023333:Proteasome B-type subunit, IPR016050:Proteasome beta-type subunit, conserved site, IPR029055:Nucleophile aminohydrolases, N-terminal" CG31742 11-Aug-17 DroID_v2017_08 "Drer\psmb8a, Drer\psmb5, Drer\si:ch211-14a17.13, Drer\psmb8f, Drer\psmb11b" Scer\PRE2 Cele\pbs-5 "Xtro\psmb5, Xtro\psmb11, Xtro\psmb8" "Mmus\Psmb8, Mmus\Psmb5, Mmus\Psmb11" "Hsap\PSMB11, Hsap\PSMB8, Hsap\PSMB5" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263576 mir-4919 mir-4919 stem loop http://flybase.org/reports/FBgn0263576 miRNA_gene - - - "mir-4919, dme-mir-4919, CR43561, miR-4919" - CR43561 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038390 Rbf2 Retinoblastoma-family protein 2 http://flybase.org/reports/FBgn0038390 protein_coding_gene "transcription factor binding ; GO:0008134 | inferred from physical interaction with Dp inferred from physical interaction with E2f2 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O77051 transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | contributes_to inferred from physical interaction with E2f2" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from genetic interaction with Rbf negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from direct assay Myb complex ; GO:0031523 | inferred from direct assay Rb-E2F complex ; GO:0035189 | traceable author statement Rb-E2F complex ; GO:0035189 | inferred from direct assay "RBF2, rbf2, CG5083, Rbf2, RB, RBf2" "IPR002719:Retinoblastoma-associated protein, B-box, IPR002720:Retinoblastoma-associated protein, A-box, IPR013763:Cyclin-like, IPR028309:Retinoblastoma protein family, IPR024599:Retinoblastoma-associated protein, N-terminal" CG5083 11-Aug-17 DroID_v2017_08 "Drer\rb1, Drer\rbl2, Drer\rbl1" - Cele\lin-35 "Xtro\rbl2, Xtro\rbl1" "Mmus\Rbl2, Mmus\Rbl1, Mmus\Rb1" "Hsap\RB1, Hsap\RBL1, Hsap\RBL2" FBgn0051942 tRNA:Arg-TCT-2-1 transfer RNA:Arginine-TCT 2-1 http://flybase.org/reports/FBgn0051942 tRNA_gene AGA codon-amino acid adaptor activity ; GO:0033447 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033447 cytosol ; GO:0005829 | inferred by curator from GO:0033447 "AE002638.trna8-ArgTCT, tRNA:R:TCT:AE002638-a, CR31942, chr2L.trna1-ArgTCT, tRNA-Arg-TCT-2-1, tRNA:Arg-TCT-2-1, tRNA:CR31942, AGA" - CR31942 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0037837 CG14693 - http://flybase.org/reports/FBgn0037837 protein_coding_gene - - - CG14693 "IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR014710:RmlC-like jelly roll fold" CG14693 11-Aug-17 DroID_v2017_08 "Drer\prkar2b, Drer\prkar1ab, Drer\prkar1aa, Drer\prkar2ab, Drer\prkar2aa, Drer\prkar1b" Scer\BCY1 Cele\B0336.12 "Xtro\prkar2a, Xtro\prkar2b, Xtro\prkar1a" "Mmus\Prkar1a, Mmus\Prkar2a, Mmus\Prkar1b, Mmus\Prkar2b, Mmus\Cnbd2" "Hsap\CNBD2, Hsap\PRKAR2B, Hsap\PRKAR2A, Hsap\PRKAR1B, Hsap\PRKAR1A" "viable,fertile,auditory perception defective" DRSC14916 E -0.240566947 0.810442391 1.64201163 0.337215676 -0.715837331 -0.504737787 FBgn0016993 ms(3)1104C ms(3)1104C http://flybase.org/reports/FBgn0016993 - gene - - - ms(3)1104C - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266631 CR45138 - http://flybase.org/reports/FBgn0266631 non_protein_coding_gene - - - CR45138 - CR45138 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002525 Lam Lamin http://flybase.org/reports/FBgn0002525 "FBgn0001930, FBgn0010582, FBgn0014344" protein_coding_gene receptor binding ; GO:0005102 | inferred from physical interaction with UniProtKB:Q8MLV1 protein binding ; GO:0005515 | inferred from physical interaction with fs(1)Ya inferred from physical interaction with Ote structural molecule activity ; GO:0005198 | inferred from mutant phenotype "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype digestive tract morphogenesis ; GO:0048546 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from direct assay positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype nuclear pore distribution ; GO:0031081 | inferred from mutant phenotype gonad morphogenesis ; GO:0035262 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype nuclear envelope organization ; GO:0006998 | inferred from mutant phenotype mitotic nuclear envelope reassembly ; GO:0007084 | inferred from direct assay centrosome organization ; GO:0051297 | inferred from mutant phenotype nuclear migration ; GO:0007097 | inferred from mutant phenotype protein localization to nuclear envelope ; GO:0090435 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype nuclear membrane organization ; GO:0071763 | inferred from direct assay chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype cell aging ; GO:0007569 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype heterochromatin maintenance involved in chromatin silencing ; GO:0070870 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype negative regulation of immune response ; GO:0050777 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype nucleus organization ; GO:0006997 | inferred from mutant phenotype" nuclear envelope ; GO:0005635 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay lamin filament ; GO:0005638 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay lamin filament ; GO:0005638 | traceable author statement "DmO, Lam, lamDm[[0]], lamin Dm0, Lam Dm[[0]], lamin Dm[[0]], lam, Dm[[0]], Dm(0), lamDm0, misg, DmLamin, Dm0, l(2)04643, Dm[[mit]], Dm[[2]], Dm[[1]], Lamin Dm[[0]], D5, Dm2, Dm1, 2459, Dmo, Dm, nlam, jf27, DM[[O]], Dm[[o]], 74/76, l(2)gdh-7, l(2)jf27, l(2)gdh7, l(2)25Ec, CG6944, Lam[[Dm0]], Lam(Dm0), LamDm[[o]], lamin, LamDm[[0]], LAM, Lamin, lamin B, Lamin B, LamDm, D[[m0]], LamDm0, lamin-B" "IPR001322:Lamin Tail Domain, IPR001664:Intermediate filament protein" CG6944 11-Aug-17 DroID_v2017_08 "Drer\desma, Drer\ngs, Drer\lmnl3, Drer\prph, Drer\krt91, Drer\desmb, Drer\cyt1, Drer\lmna, Drer\neflb, Drer\viml, Drer\gfap, Drer\nefma, Drer\vim, Drer\krt5, Drer\zgc:77517, Drer\zgc:65851, Drer\lmnb2, Drer\inab, Drer\si:dkey-222n6.2, Drer\zgc:172323, Drer\nefmb, Drer\zgc:171226, Drer\nefla, Drer\krt97, Drer\krt15, Drer\krt4, Drer\inaa, Drer\krt8, Drer\lmnb1" - "Cele\ifd-1, Cele\ifa-3, Cele\ifa-1, Cele\ifc-1, Cele\ifd-2, Cele\F10C1.8, Cele\ifc-2, Cele\ifa-4, Cele\mua-6, Cele\ifp-1, Cele\ifb-1, Cele\ifb-2, Cele\lmn-1" "Xtro\lmnb3, Xtro\krt18, Xtro\krt5.7, Xtro\krt, Xtro\krt8, Xtro\nif, Xtro\des.1, Xtro\krt17, Xtro\vim, Xtro\nefl, Xtro\vim.2, Xtro\krt5.2, Xtro\prph, Xtro\ina, Xtro\krt19, Xtro\lmnb1, Xtro\lmnb2, Xtro\lmna" "Mmus\Vim, Mmus\Krt36, Mmus\Krt19, Mmus\Krt35, Mmus\Des, Mmus\Krt79, Mmus\Krt6a, Mmus\Krt5, Mmus\Ina, Mmus\Krt17, Mmus\Krt6b, Mmus\Lmntd1, Mmus\Krt90, Mmus\Krt42, Mmus\Krt16, Mmus\Lmntd2, Mmus\Krt75, Mmus\Gfap, Mmus\Lmnb2, Mmus\Krt15, Mmus\Nefl, Mmus\Krt8, Mmus\Lmnb1, Mmus\Lmna, Mmus\Krt13, Mmus\Krt14, Mmus\Nefm" "Hsap\KRT5, Hsap\KRT7, Hsap\KRT8, Hsap\KRT76, Hsap\KRT6B, Hsap\LMNTD2, Hsap\KRT33A, Hsap\KRT13, Hsap\KRT10, Hsap\VIM, Hsap\KRT33B, Hsap\KRT31, Hsap\KRT16, Hsap\NEFH, Hsap\LMNA, Hsap\KRT14, Hsap\LMNB1, Hsap\KRT12, Hsap\KRT3, Hsap\CFAP53, Hsap\LMNB2, Hsap\KRT17, Hsap\NEFL, Hsap\KRT6C, Hsap\KRT15, Hsap\LMNTD1, Hsap\DES, Hsap\KRT9, Hsap\KRT35, Hsap\LOC100653049, Hsap\KRT75, Hsap\NEFM, Hsap\KRT19, Hsap\INA, Hsap\GFAP" " embryonic stage -- adult stage , embryonic stage " " embryonic stage , embryonic stage -- adult stage , embryonic stage | early , larval stage , oogenesis stage " "lethal,partially lethal - majority die,locomotor behavior defective,gravitaxis defective,viable,fertile,sterile,female sterile,recessive,male sterile,partially,flightless,uncoordinated,flight defective,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,some die during third instar larval stage,wild-type,female,germline clone,developmental rate defective,cell growth defective,partially lethal - majority live,visible,short lived,temperature conditional" "presumptive embryonic/larval muscle system,ovary,ovariole,oocyte,spermatozoon,nuclear pore,annulate lamellae,nuclear membrane,eye disc & nucleus | ectopic | somatic clone,presumptive embryonic/larval tracheal system,egg chamber,germline clone,egg,dorsal appendage,supernumerary,nurse cell,dorsal branch primordium,ganglionic branch primordium,nucleus & eye photoreceptor cell & eye disc,nuclear inner membrane,nuclear outer membrane,gamete,female,nuclear membrane | pharate adult stage,pigment cell,adult cuticle,cystocyte & nucleus & pharate adult,gonad | male & pharate adult,eye & nucleus & pharate adult,subesophageal ganglion,adult midgut,longitudinal muscle,eye,rhabdomerecl-h4),eye disc & nucleus | ectopiccl-h4),rhabdomere,eye disc & nucleus | ectopic,ommatidium,nucleus | adult stageMhc.Switch.PO,adult fat body,nucleus | adult stageSwitch1.106,brain,nucleus | adult stageelav.Switch.PO,chaeta,trichogen cell,cyst progenitor cell,germline stem cell,cyst cell,male germline cell" FBgn0027587 CG7028 - http://flybase.org/reports/FBgn0027587 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 protein kinase activity ; GO:0004672 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from biological aspect of ancestor with PANTHER:PTN000623619" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "FBgn0027587, BcDNA:GH04978, PRP4, prp4, CG7028" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG7028 11-Aug-17 DroID_v2017_08 "Drer\prpf4ba, Drer\prpf4bb" "Scer\CAK1, Scer\YAK1" Cele\prpf-4 Xtro\prpf4b "Mmus\Cdk12, Mmus\Prpf4b" Hsap\PRPF4B "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0001257 ImpL2 Ecdysone-inducible gene L2 http://flybase.org/reports/FBgn0001257 - protein_coding_gene insulin-like growth factor binding ; GO:0005520 | inferred from physical interaction with Ilp2 inferred from physical interaction with Ilp6 inferred from physical interaction with Ilp5 inferred from physical interaction with Ilp4 inferred from physical interaction with Ilp1 cell adhesion ; GO:0007155 | traceable author statement negative regulation of lipid storage ; GO:0010888 | inferred from mutant phenotype positive regulation of insulin receptor signaling pathway ; GO:0046628 | inferred from direct assay negative regulation of insulin receptor signaling pathway ; GO:0046627 | inferred from genetic interaction with Ilp2 inferred from genetic interaction with InR determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "ImpL2, IMPL2, Imp-L2, Imp-12, CT34862, IMP-L2, CG15009, ImpL-2, GH28" "IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003599:Immunoglobulin subtype" CG15009 11-Aug-17 DroID_v2017_08 Drer\bsg - "Cele\zig-4, Cele\zig-3, Cele\zig-2, Cele\zig-5" Xtro\lsamp - - " embryonic stage | stage 8 , embryonic stage | stage 15-16 , embryonic stage | stage 9 , embryonic stage | stage 15-17 , embryonic stage | stage 15,16 , embryonic stage | cellular blastoderm " " neurogenic region

, embryonic/larval esophagus

, tracheal pit

, embryonic/larval pharynx

, bipolar dendrite neuron

, embryonic/larval posterior spiracle

, frontal head air sac

,

pair-rule " " embryonic stage | stage 16-17 , embryonic stage | stage 16,17 " " embryonic optic lobe primordium

, bipolar dendrite neuron

, procephalic segment

, multidendritic neuron

" "viable,fertile,hyperplasia,large body,stress response defective,lethal,small body,decreased cell size,somatic clone,developmental rate defective,long lived,female limited,RU486 conditional,short lived,wild-type" "ovary,eye" DRSC08666 K 0.091502141 -0.661047689 -0.522718027 -0.000434487 0.215414036 -1.501459974 FBgn0011570 cpb capping protein beta http://flybase.org/reports/FBgn0011570 "FBgn0015012, FBgn0061517" protein_coding_gene actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000065509 actin binding ; GO:0003779 | inferred from sequence or structural similarity protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with cpa "microtubule-based movement ; GO:0007018 | inferred by curator from GO:0005869 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype barbed-end actin filament capping ; GO:0051016 | inferred from direct assay cell morphogenesis ; GO:0000902 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype regulation of actin filament length ; GO:0030832 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype barbed-end actin filament capping ; GO:0051016 | inferred from mutant phenotype negative regulation of filopodium assembly ; GO:0051490 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype regulation of lamellipodium assembly ; GO:0010591 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with cpa cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype" F-actin capping protein complex ; GO:0008290 | inferred from direct assay actin filament ; GO:0005884 | inferred from biological aspect of ancestor with PANTHER:PTN000065509 adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay WASH complex ; GO:0071203 | inferred from sequence or structural similarity with UniProtKB:P47756 dynactin complex ; GO:0005869 | inferred from sequence or structural similarity with MGI:MGI:104652 "bnd, CP, CapZ, CP-beta, CG17158, J, cpb, Cpb, CapZbeta, CPB, CAPB_DROME, Cap2, cpbeta" "IPR001698:F-actin-capping protein subunit beta, IPR019771:F-actin capping protein, beta subunit, conserved site" CG17158 11-Aug-17 DroID_v2017_08 Drer\capzb Scer\CAP2 Cele\cap-2 Xtro\capzb Mmus\Capzb Hsap\CAPZB embryonic stage -- adult stage " adult stage , embryonic stage -- adult stage " " muscle cell &&of thorax

, macrochaeta

" "wild-type,visible,recessive,somatic clone,lethal,cell migration defective,partially lethal - majority die,developmental rate defective,fertile,male,semi-sterile,dominant,female,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective" "eye,somatic clone,ommatidium,eye photoreceptor cell,interommatidial bristle,wing,adult abdomen,chaeta,eye photoreceptor cell & nucleus | somatic clone,border follicle cell,wing disc,rhabdomere,filopodium | supernumerary,trichogen cell & actin filament & pupa,sternopleural bristle,macrochaeta,egg,maternal effect,actin filament & egg chamber,nurse cell,macrochaeta & head,macrochaeta & thorax,actin cytoskeleton & eye disc | somatic clone,actin filament & dorsal mesothoracic disc & pupa | somatic clone,NMJ bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0060810 l(3)S054516 lethal (3) S054516 http://flybase.org/reports/FBgn0060810 gene - - - "0545/16, l(3)S054516" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038072 CG6225 - http://flybase.org/reports/FBgn0038072 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from electronic annotation with InterPro:IPR033740 neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG6225 "IPR000994:Peptidase M24, IPR033740:Aminopeptidase P, IPR029149:Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR028980:Creatinase/Aminopeptidase P, N-terminal, IPR000587:Creatinase, N-terminal, IPR032416:Peptidase M24, C-terminal domain" CG6225 11-Aug-17 DroID_v2017_08 "Drer\xpnpep2, Drer\xpnpep1" Scer\FRA1 "Cele\app-1, Cele\Y45G5AM.2" Xtro\xpnpep2 "Mmus\Xpnpep1, Mmus\Xpnpep2" "Hsap\XPNPEP2, Hsap\XPNPEP1" "lethal,neuroanatomy defective,viable,visible,body color defective" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0015268 Nap1 Nucleosome assembly protein 1 http://flybase.org/reports/FBgn0015268 - protein_coding_gene histone binding ; GO:0042393 | traceable author statement histone binding ; GO:0042393 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay nucleosome assembly ; GO:0006334 | inferred from direct assay telomere maintenance ; GO:0000723 | inferred from mutant phenotype sperm chromatin condensation ; GO:0035092 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from direct assay sperm chromatin decondensation ; GO:0035041 | inferred from direct assay" ACF complex ; GO:0016590 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "NAP1, NAP-1, dNAP-1, Nap-1, dNAP1, p56/dCAF-4, dNap1, CG5330, Nap1, nap1, Kette, nap-1, dCAF-4, p56" IPR002164:Nucleosome assembly protein (NAP) CG5330 11-Aug-17 DroID_v2017_08 "Drer\nap1l1, Drer\nap1l4a, Drer\nap1l4b" "Scer\VPS75, Scer\NAP1" Cele\nap-1 "Xtro\nap1l1, Xtro\nap1l4" "Mmus\Nap1l3, Mmus\Nap1l2, Mmus\Nap1l5, Mmus\Nap1l4, Mmus\Nap1l1" "Hsap\NAP1L3, Hsap\NAP1L2, Hsap\NAP1L4, Hsap\NAP1L1, Hsap\NAP1L5" " embryonic stage -- adult stage , embryonic stage | early " "viable,fertile,wild-type,suppressor of variegation,dominant,lethal,visible,partially lethal - majority die,some die during pupal stage" "investment cone,trichogen cell,mesothoracic tergum,eye" DRSC04626 K 0.252295169 0.308294835 -0.333035488 0.168113061 -1.530143096 1.261653866 FBgn0003867 tsl torso-like http://flybase.org/reports/FBgn0003867 - protein_coding_gene - "torso signaling pathway ; GO:0008293 | traceable author statement terminal region determination ; GO:0007362 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement embryonic pattern specification ; GO:0009880 | inferred from expression pattern inferred from mutant phenotype torso signaling pathway ; GO:0008293 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from direct assay "fs(3)00617, CG6705, tsl, Dm-tsl, Tsl" IPR020864:Membrane attack complex component/perforin (MACPF) domain CG6705 11-Aug-17 DroID_v2017_08 - - - - - - adult stage && oogenesis stage " follicle cell | posterior

, border follicle cell

, centripetally migrating follicle cell

" " embryonic stage | stage 13 , embryonic stage | stage 4 , embryonic stage | 0-9 hr " " embryonic/larval tracheal system

, organism | 80-100% egg length

, ventral nervous system

, organism | 0-20% egg length

, vitelline membrane

anterior & posterior " "developmental rate defective,female sterile,recessive,reduced,lethal,heat sensitive,wild-type,maternal effect,viable,visible,size defective,decreased cell size" "dorsal bridge,embryonic/first instar larval cuticle,denticle belt,abdominal segment 8,anal pad,abdominal 11 anal tuft,posterior spiracle primordium,filzkorper,head,embryonic/larval spiracle,ectopic,mouthpart,embryonic segment,ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 9,abdominal segment 10,telson,labrum,ocular segment,cephalic furrow,cephalopharyngeal skeleton,embryonic abdominal segment 8,embryo,anterior,posterior,embryonic head,embryonic telson,abdominal 8 ventral denticle belt,maternal effect,terminalia,embryonic thorax,embryonic abdomen,wing hair" FBgn0023023 CRMP Collapsin Response Mediator Protein http://flybase.org/reports/FBgn0023023 "FBgn0027906, FBgn0062660" protein_coding_gene dihydropyrimidinase activity ; GO:0004157 | inferred from direct assay 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from genetic interaction with r Ras protein signal transduction ; GO:0007265 | inferred from genetic interaction with Ras85D centrosome localization ; GO:0051642 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011778 "Pyd2, EP(3)3238, EP3238, l(3)83Ba, CG1411, BcDNA:HL02693, CRMP, DHP, crmp, pyd2" "IPR006680:Amidohydrolase-related, IPR011059:Metal-dependent hydrolase, composite domain, IPR011778:Hydantoinase/dihydropyrimidinase, IPR032466:Metal-dependent hydrolase" CG1411 11-Aug-17 DroID_v2017_08 "Drer\dpysl3, Drer\zgc:103559, Drer\dpysl2a, Drer\dpys, Drer\dpysl5a, Drer\crmp1, Drer\dpysl5b, Drer\dpysl4, Drer\dpysl2b" Scer\DAL1 "Cele\dhp-1, Cele\unc-33, Cele\dhp-2" "Xtro\dpysl4, Xtro\LOC100498039, Xtro\crmp1, Xtro\dpysl5, Xtro\dpys, Xtro\dpysl3" "Mmus\Dpysl4, Mmus\Dpys, Mmus\Dpysl3, Mmus\Dpysl2, Mmus\Dpysl5, Mmus\Crmp1" "Hsap\CRMP1, Hsap\DPYS, Hsap\DPYSL3, Hsap\DPYSL4, Hsap\DPYSL5, Hsap\DPYSL2" "chemical sensitive,viable,fertile,memory defective,circadian behavior defective,recessive" "external sensory organ precursor cell I,somatic clone,centrosome | somatic clone,centrosomeneur-P72" FBgn0010637 l(2)07206 lethal (2) 07206 http://flybase.org/reports/FBgn0010637 - gene - - - l(2)07206 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001579 l(1)AL1 lethal (1) AL1 http://flybase.org/reports/FBgn0001579 - gene - - - l(1)AL1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,short lived" FBgn0060700 l(3)S071802b lethal (3) S071802b http://flybase.org/reports/FBgn0060700 gene - - - "0718/02, l(3)S071802b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003174 pwn pawn http://flybase.org/reports/FBgn0003174 FBgn0033157 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" lateral inhibition ; GO:0046331 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype - "CG11101, CT31067, l(2)pwn, pwn, pawn" "IPR000742:EGF-like domain, IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site" CG11101 11-Aug-17 DroID_v2017_08 - - - - Mmus\Umodl1 - "viable,fertile,neurophysiology defective,partially lethal - majority die,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,germline clone" "chaeta,eye,microvillus & rhabdomere | distal,retina,macrochaeta,cornea" FBgn0037824 CG14684 - http://flybase.org/reports/FBgn0037824 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cell cycle ; GO:0051726 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available CG14684 - CG14684 11-Aug-17 DroID_v2017_08 - - Cele\tbca-1 - - - viable FBgn0260613 2L2366 - http://flybase.org/reports/FBgn0260613 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2366 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "dorsal air sac primordium,somatic clone" FBgn0001030 Fs(3)Ber Female sterile (3) Bercel http://flybase.org/reports/FBgn0001030 - gene - - - "Fs(3)Bercel, Fs(3)Sz4, Fs(3)Ber" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0003520 stau staufen http://flybase.org/reports/FBgn0003520 - protein_coding_gene mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from sequence or structural similarity double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with mira mRNA binding ; GO:0003729 | non-traceable author statement microtubule binding ; GO:0008017 | non-traceable author statement double-stranded RNA binding ; GO:0003725 | traceable author statement "microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity bicoid mRNA localization ; GO:0045450 | traceable author statement pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement pole plasm assembly ; GO:0007315 | non-traceable author statement pole plasm protein localization ; GO:0007318 | traceable author statement regulation of pole plasm oskar mRNA localization ; GO:0007317 | traceable author statement oogenesis ; GO:0048477 | traceable author statement protein localization ; GO:0008104 | traceable author statement protein localization to synapse ; GO:0035418 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | non-traceable author statement positive regulation of oskar mRNA translation ; GO:0046012 | non-traceable author statement positive regulation of cytoplasmic mRNA processing body assembly ; GO:0010606 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype pole plasm mRNA localization ; GO:0019094 | traceable author statement regulation of oskar mRNA translation ; GO:0046011 | traceable author statement intracellular mRNA localization ; GO:0008298 | traceable author statement anterior/posterior axis specification, embryo ; GO:0008595 | inferred from genetic interaction with mira pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype long-term memory ; GO:0007616 | traceable author statement pole plasm assembly ; GO:0007315 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype pole plasm RNA localization ; GO:0007316 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | traceable author statement bicoid mRNA localization ; GO:0045450 | non-traceable author statement regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from genetic interaction with mira RNA localization ; GO:0006403 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | traceable author statement" cytoplasm ; GO:0005737 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay subsynaptic reticulum ; GO:0071212 | inferred from direct assay basal cortex ; GO:0045180 | non-traceable author statement basal plasma membrane ; GO:0009925 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay basal cortex ; GO:0045180 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity basal cortex ; GO:0045180 | inferred from direct assay germ plasm ; GO:0060293 | inferred from direct assay "Stau, dStau, STAU, Dmstau, CG5753, stau, Stauf" "IPR014720:Double-stranded RNA-binding domain, IPR032478:Staufen, C-terminal" CG5753 11-Aug-17 DroID_v2017_08 "Drer\prkra, Drer\stau2, Drer\stau1, Drer\tarbp2" - Cele\stau-1 "Xtro\stau1, Xtro\stau2, Xtro\tarbp2, Xtro\adarb1" "Mmus\Prkra, Mmus\Tarbp2, Mmus\Stau1, Mmus\Adarb1, Mmus\Stau2" "Hsap\TARBP2, Hsap\STAU1, Hsap\STAU2, Hsap\PRKRA" " adult stage && oogenesis stage | stage S6 , adult stage && oogenesis stage | stage S6-10 , adult stage && oogenesis stage | stage S3-4 , egg stage | fertilized egg " " oocyte | presumptive

, nurse cell

, female germline stem cell

, fertilized egg | ubiquitous

" " embryonic stage | stage 13 , oogenesis stage | stage S6-8 , oogenesis stage | stage S3-4 , embryonic stage | stage 1 , adult stage && oogenesis stage | stage >=S10B , adult stage && oogenesis stage | stage S10 , embryonic stage | extended germ band , embryonic stage | early , adult stage , adult stage && oogenesis stage | stage S8-10B " " central nervous system

, polar follicle cell

posterior , oocyte | presumptive

,

terminal , nurse cell

, organism | 90-100% egg length

, oocyte | posterior

, embryonic nervous system

, organism | anterior

, pole plasm

, stage S11 oocyte | anterior

, organism | posterior

, organism | 0-10% egg length

" "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,germline clone,non-rescuable maternal effect,wild-type,memory defective,heat sensitive,lethal,male sterile,female sterile,grandchildless,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,somatic clone" "embryonic head,maternal effect,embryonic abdomen,germline clone,embryo,posterior,pole cell,abdominal segment,pole granule,embryonic abdominal segment,cephalic furrow,anterior,pole plasm,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,RP2 motor neuron,somatic clone" FBgn0004691 rss reduced scutellars and sternitals http://flybase.org/reports/FBgn0004691 - gene - - - rss - - 11-Aug-17 DroID_v2017_08 - - - - - - "scutellar bristle,sternite" FBgn0001822 l(1)tl lethal (1) tracheae lacking http://flybase.org/reports/FBgn0001822 - gene - - - l(1)tl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" embryonic/larval tracheal system FBgn0004865 Eip78C Ecdysone-induced protein 78C http://flybase.org/reports/FBgn0004865 "FBgn0046387, FBgn0046388" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628 steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with HGNC:7963" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR001723" "CG18023, E78B, E78, E78A, DR-78, Eip78, NR1E1, dE78, E78D, Eip78D, anon-WO0172774.44, anon-WO0172774.42, Eip78C, EIP78C, Eip 78C" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG18023 11-Aug-17 DroID_v2017_08 "Drer\rorca, Drer\pparg, Drer\pparda, Drer\nr1d4b, Drer\nr1d2a, Drer\pparaa, Drer\rarab, Drer\pparab, Drer\rorcb, Drer\nr1d4a, Drer\rorab, Drer\nr1d1, Drer\roraa, Drer\raraa, Drer\rarga, Drer\nr1d2b, Drer\ppardb, Drer\rorb" - "Cele\nhr-68, Cele\nhr-285, Cele\nhr-42, Cele\nhr-259, Cele\sex-1, Cele\nhr-38, Cele\nhr-115, Cele\nhr-58, Cele\nhr-53, Cele\nhr-85, Cele\nhr-223, Cele\nhr-164, Cele\nhr-219, Cele\nhr-174, Cele\unc-55, Cele\nhr-47, Cele\nhr-193, Cele\nhr-92, Cele\nhr-273, Cele\nhr-134, Cele\dpr-1, Cele\nhr-130, Cele\nhr-222, Cele\nhr-146, Cele\nhr-142, Cele\nhr-107, Cele\nhr-175, Cele\nhr-37, Cele\nhr-65, Cele\nhr-205, Cele\nhr-232, Cele\nhr-64, Cele\nhr-95, Cele\nhr-157, Cele\nhr-262, Cele\nhr-150, Cele\nhr-112, Cele\nhr-286, Cele\nhr-225, Cele\nhr-127, Cele\nhr-210, Cele\Y47D7A.3, Cele\nhr-181, Cele\nhr-78, Cele\nhr-156, Cele\nhr-23, Cele\nhr-48, Cele\nhr-50, Cele\srt-58, Cele\nhr-45, Cele\nhr-212, Cele\nhr-198, Cele\nhr-216, Cele\nhr-192, Cele\nhr-275, Cele\nhr-183, Cele\nhr-269, Cele\nhr-1, Cele\nhr-117, Cele\nhr-155, Cele\nhr-99, Cele\nhr-255, Cele\nhr-287, Cele\nhr-138, Cele\nhr-226, Cele\nhr-265, Cele\nhr-19, Cele\nhr-26, Cele\nhr-74, Cele\nhr-76, Cele\nhr-169, Cele\nhr-139, Cele\nhr-166, Cele\nhr-123, Cele\nhr-30, Cele\nhr-201, Cele\nhr-55, Cele\nhr-63, Cele\nhr-229, Cele\nhr-199, Cele\nhr-203, Cele\nhr-71, Cele\nhr-126, Cele\nhr-180, Cele\nhr-163, Cele\nhr-27, Cele\nhr-176, Cele\nhr-252, Cele\nhr-62, Cele\nhr-113, Cele\nhr-10, Cele\nhr-172, Cele\nhr-80, Cele\nhr-248, Cele\nhr-213, Cele\nhr-170, Cele\nhr-16, Cele\nhr-114, Cele\nhr-70, Cele\nhr-159, Cele\nhr-39, Cele\nhr-98, Cele\nhr-211, Cele\nhr-20, Cele\nhr-110, Cele\nhr-243, Cele\nhr-178, Cele\nhr-260, Cele\nhr-44, Cele\nhr-167, Cele\nhr-12, Cele\nhr-283, Cele\nhr-73, Cele\nhr-242, Cele\nhr-13, Cele\nhr-40, Cele\nhr-179, Cele\nhr-33, Cele\nhr-257, Cele\nhr-52, Cele\nhr-108, Cele\nhr-237, Cele\nhr-245, Cele\nhr-254, Cele\nhr-280, Cele\nhr-190, Cele\nhr-121, Cele\nhr-128, Cele\nhr-54, Cele\nhr-197, Cele\nhr-4, Cele\nhr-171, Cele\nhr-77, Cele\nhr-32, Cele\nhr-94, Cele\nhr-238, Cele\nhr-261, Cele\nhr-158, Cele\nhr-21, Cele\nhr-106, Cele\nhr-256, Cele\nhr-9, Cele\nhr-281, Cele\nhr-59, Cele\nhr-184, Cele\nhr-132, Cele\nhr-145, Cele\nhr-186, Cele\nhr-230, Cele\nhr-185, Cele\nhr-87, Cele\nhr-231, Cele\nhr-56, Cele\nhr-125, Cele\nhr-165, Cele\nhr-103, Cele\daf-12, Cele\nhr-217, Cele\nhr-104, Cele\nhr-218, Cele\nhr-162, Cele\nhr-81, Cele\nhr-140, Cele\nhr-258, Cele\nhr-84, Cele\nhr-131, Cele\nhr-271, Cele\nhr-161, Cele\nhr-264, Cele\nhr-187, Cele\nhr-214, Cele\nhr-288, Cele\nhr-96, Cele\nhr-268, Cele\nhr-189, Cele\nhr-124, Cele\nhr-282, Cele\nhr-235, Cele\nhr-57, Cele\nhr-241, Cele\nhr-194, Cele\nhr-182, Cele\nhr-18, Cele\nhr-102, Cele\nhr-188, Cele\nhr-234, Cele\nhr-195, Cele\nhr-90, Cele\nhr-72, Cele\ZK418.11, Cele\nhr-244, Cele\nhr-267, Cele\nhr-43, Cele\nhr-105, Cele\nhr-101, Cele\nhr-177, Cele\nhr-2, Cele\nhr-82, Cele\nhr-135, Cele\nhr-233, Cele\nhr-79, Cele\nhr-15, Cele\nhr-227, Cele\nhr-109, Cele\nhr-7, Cele\nhr-122, Cele\nhr-143, Cele\nhr-202, Cele\nhr-274, Cele\nhr-3, Cele\nhr-86, Cele\nhr-66, Cele\nhr-46, Cele\nhr-28, Cele\nhr-247, Cele\nhr-89, Cele\nhr-61, Cele\nhr-270, Cele\nhr-251, Cele\nhr-272, Cele\nhr-196, Cele\nhr-133, Cele\nhr-11, Cele\nhr-51, Cele\ZK1037.13, Cele\nhr-22, Cele\nhr-253, Cele\nhr-228" "Xtro\rorb.2, Xtro\rara, Xtro\rarg, Xtro\rorc, Xtro\rora, Xtro\rarb, Xtro\nr1d2" "Mmus\Ppara, Mmus\Nr1d1, Mmus\Rarg, Mmus\Rarb, Mmus\Rorc, Mmus\Pparg, Mmus\Rara, Mmus\Rora, Mmus\Ppard, Mmus\Nr1d2, Mmus\Rorb" "Hsap\RARB, Hsap\PPARD, Hsap\RARA, Hsap\NR1D2, Hsap\RARG, Hsap\PPARG, Hsap\PPARA, Hsap\RORC, Hsap\NR1D1, Hsap\RORB, Hsap\RORA" " larval stage | 32-48 hr , L | third instar stage 2-- P | stage P4 , larval stage | third instar stage 2-- P | stage P4 , pupal stage | 48-56 hr , third instar larval stage L2-- prepupal stage | stage P4 , larval stage | third instar stage 2--P | stage P4 " organism

"viable,fertile,female fertile,male fertile,visible,partially lethal - majority die,some die during pupal stage" "ommatidium,eye,dorsal appendage" FBgn0011241 cbx crossbronx http://flybase.org/reports/FBgn0011241 FBgn0033456 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000003026 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype histone ubiquitination ; GO:0016574 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 spermatid development ; GO:0007286 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000003026 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 sperm individualization ; GO:0007291 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000630652 HULC complex ; GO:0033503 | inferred from biological aspect of ancestor with PANTHER:PTN000630652 "cbx, CG10536, Ft1, ms(2)46C, ms(2)05704, Cbx" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG10536 11-Aug-17 DroID_v2017_08 Drer\aktip Scer\RAD6 Cele\ubc-19 Xtro\aktip Mmus\Aktip Hsap\AKTIP "viable,fertile,male sterile,recessive,neuroanatomy defective,somatic clone" "spermatid,crystal cell,spermatozoon,primary spermatocyte cyst,spermatid & nucleus,neuroblast,somatic clone" FBgn0001522 l(1)11Da lethal (1) 11Da http://flybase.org/reports/FBgn0001522 - gene - - - l(1)11Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0028639 ifm(2)RU3 indirect flight muscle (2) RU3 http://flybase.org/reports/FBgn0028639 gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay ifm(2)RU3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,flight defective,fertile,viable,reduced,lethal,flightless" "wing,dorsal medial muscle,indirect flight muscle" FBgn0027963 l(3)S145709 lethal (3) S145709 http://flybase.org/reports/FBgn0027963 gene - - - "1457/09, l(3)S145709" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069318 X-183-12 X-183-12 http://flybase.org/reports/FBgn0069318 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-183-12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,recessive,rescuable maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0037783 Npc2c Niemann-Pick type C-2c http://flybase.org/reports/FBgn0037783 protein_coding_gene sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 intracellular cholesterol transport ; GO:0032367 | inferred from electronic annotation with InterPro:IPR033916 sterol transport ; GO:0015918 | inferred from sequence or structural similarity with Npc2a neurogenesis ; GO:0022008 | inferred from mutant phenotype - "DmML5A, npc2c, Npc2c, CG3934" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set, IPR033916:ML domain, Npc2 like" CG3934 11-Aug-17 DroID_v2017_08 "Drer\npc2, Drer\zgc:193725" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0061198 HSPC300 Haematopoietic stem/progenitor cell protein 300 http://flybase.org/reports/FBgn0061198 protein_coding_gene "protein complex binding ; GO:0032403 | inferred from electronic annotation with InterPro:IPR033378 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:B1Q236,UniProtKB:P55162,UniProtKB:Q9VF87,UniProtKB:Q9VKM2,UniProtKB:Q9Y0S9" protein oligomerization ; GO:0051259 | inferred from direct assay regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype central nervous system morphogenesis ; GO:0021551 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of actin polymerization or depolymerization ; GO:0008064 | inferred from biological aspect of ancestor with PANTHER:PTN002133680 positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype positive regulation of lamellipodium assembly ; GO:0010592 | inferred from mutant phenotype cell motility ; GO:0048870 | inferred from biological aspect of ancestor with PANTHER:PTN002133680 SCAR complex ; GO:0031209 | inferred from direct assay "HSPC300, CG30173, SIP1, dHSPC, Brk1, dHSPC300" IPR033378:Protein BRICK1 CG30173 11-Aug-17 DroID_v2017_08 Drer\brk1 - Cele\nuo-3 Xtro\brk1 Mmus\Brk1 Hsap\BRK1 "lethal,recessive,maternal effect,neuroanatomy defective,dominant,partially,viable,cell shape defective,visible,planar polarity defective" "presumptive embryonic/larval central nervous system,maternal effect,longitudinal connective,ventral nerve cord commissure,embryonic/larval neuromuscular junction,mesothoracic bristle,chaeta,supernumerary" DRSC22880 I 1.547867006 0.220774459 -0.241300541 0.077786401 -0.005323899 -0.225236162 FBgn0004901 Prat Phosphoribosylamidotransferase http://flybase.org/reports/FBgn0004901 - protein_coding_gene amidophosphoribosyltransferase activity ; GO:0004044 | inferred from sequence or structural similarity inferred from mutant phenotype nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000836 purine nucleobase biosynthetic process ; GO:0009113 | inferred from electronic annotation with InterPro:IPR005854 embryonic cleavage ; GO:0040016 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype purine nucleobase biosynthetic process ; GO:0009113 | inferred from sequence or structural similarity purine nucleotide biosynthetic process ; GO:0006164 | inferred from mutant phenotype - "CG2867, Prat, DmPrat" "IPR005854:Amidophosphoribosyltransferase, IPR017932:Glutamine amidotransferase type 2 domain, IPR029055:Nucleophile aminohydrolases, N-terminal, IPR029057:Phosphoribosyltransferase-like, IPR000836:Phosphoribosyltransferase domain" CG2867 11-Aug-17 DroID_v2017_08 Drer\ppat "Scer\YMR084W, Scer\ADE4" Cele\ppat-1 Xtro\ppat Mmus\Ppat Hsap\PPAT "lethal,recessive,partially lethal - majority die,visible,aging defective,dominant,female,partially,short lived,conditional,maternal effect,melanotic necrosis,increased cell death,some die during pupal stage,female sterile,viable" "posterior crossvein,follicle cell,border follicle cell,nurse cell & nucleus,oocyte,egg chamber,cycle 6 embryo,maternal effect,cycle 7 embryo,cycle 8 embryo,cycle 9 embryo,cycle 10 embryo,cycle 11 embryo,cycle 12 embryo,cycle 13 embryo,polar body nucleus,yolk nucleus,cleavage nucleus,nurse cell & nucleusdsx43),embryonic abdominal segment,larval abdominal segment,wing,leg,wing disc,tergite | pharate adult stage" FBgn0000721 for foraging http://flybase.org/reports/FBgn0000721 "FBgn0000443, FBgn0010629, FBgn0031555, FBgn0044607, FBgn0063202, FBgn0066013" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR002374, InterPro:IPR017441 cGMP-dependent protein kinase activity ; GO:0004692 | inferred from direct assay cyclic nucleotide-dependent protein kinase activity ; GO:0004690 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" regulation of heart contraction ; GO:0008016 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype regulation of response to food ; GO:0032095 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement short-term memory ; GO:0007614 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay feeding behavior ; GO:0007631 | traceable author statement response to sucrose ; GO:0009744 | inferred from direct assay larval feeding behavior ; GO:0030536 | inferred from mutant phenotype regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "for, FOR/PKG, 142251_at, dg2, CG10033, DG2, PKG, l(2)06860, Pkg24A, Pkg2, Dg2, BcDNA:GM08338, anon-WO02059370.47, anon-WO0140519.260, For" "IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR002374:cGMP-dependent kinase, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR014710:RmlC-like jelly roll fold, IPR017441:Protein kinase, ATP binding site, IPR031831:cGMP-dependent protein kinase, N-terminal coiled-coil domain" CG10033 11-Aug-17 DroID_v2017_08 "Drer\prkacbb, Drer\LOC556339, Drer\prkacba, Drer\prkacaa, Drer\prkg1b, Drer\prkg1l, Drer\prkacab, Drer\prkg2, Drer\prkg1a, Drer\prkx, Drer\si:dkey-121j17.5" "Scer\TPK2, Scer\TPK3, Scer\TPK1" "Cele\pkg-2, Cele\egl-4" "Xtro\prkx, Xtro\prkacb, Xtro\prkaca, Xtro\prkg1, Xtro\prkg2" "Mmus\Prkg1, Mmus\Prkg2, Mmus\Prkx, Mmus\Prkaca, Mmus\Prkacb" "Hsap\PRKG1, Hsap\PRKX, Hsap\PRKG2, Hsap\PRKACG, Hsap\PRKACB, Hsap\PRKACA" "learning defective,lethal,wild-type,chemical resistant,heat sensitive,recessive,viable,fertile,dominant,hyperactive,behavior defective,neurophysiology defective,semidominant,memory defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,hypoactive,short lived,RU486 conditional,locomotor behavior defective,visible,partially lethal - majority die" "crystal cell,adult heart,axon terminus | larval stage,embryonic/larval tracheal system,adult Malpighian tubule,mesothoracic tergum" DRSC00195 I -0.864213044 -1.521181525 -0.542813679 0.130915826 0.639699844 0.586525244 FBgn0005558 ey eyeless http://flybase.org/reports/FBgn0005558 "FBgn0000616, FBgn0004525, FBgn0004547, FBgn0010156" protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with so transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from mutant phenotype RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VBW6 inferred from physical interaction with UniProtKB:Q9VBW9 sequence-specific DNA binding ; GO:0043565 | inferred from mutant phenotype" "mushroom body development ; GO:0016319 | inferred from expression pattern inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype regulation of insulin-like growth factor receptor signaling pathway ; GO:0043567 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay compound eye development ; GO:0048749 | traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | traceable author statement positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay glial cell migration ; GO:0008347 | inferred from mutant phenotype neuron differentiation ; GO:0030182 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype central complex development ; GO:0048036 | inferred from mutant phenotype photoreceptor cell fate specification ; GO:0043704 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype" nucleus ; GO:0005634 | traceable author statement "ey, Ey, Pax-6, Pax6, Ey/Pax6, pax6, CG1464, eye, DPax-6, EYEL, l(4)33, l(4)102CDr, l(4)102CDh, EY, OK107" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG1464 11-Aug-17 DroID_v2017_08 "Drer\pax2b, Drer\lhx6, Drer\pax7a, Drer\ldb3a, Drer\pax6b, Drer\arxa, Drer\pax9, Drer\mxtx2, Drer\pax4, Drer\pax7b, Drer\pax3a, Drer\shox, Drer\hoxb8a, Drer\pax1b, Drer\pax6a, Drer\shox2, Drer\arxb, Drer\pitx3, Drer\pax3b, Drer\pitx1, Drer\gsc, Drer\pdlim3b, Drer\pax10, Drer\dmbx1b, Drer\pdlim7, Drer\pax8, Drer\pax2a, Drer\pax5, Drer\mxtx1, Drer\dmbx1a, Drer\pax1a, Drer\mixl1" "Scer\PHO2, Scer\YHP1, Scer\PXL1" "Cele\ceh-51, Cele\lim-4, Cele\egl-38, Cele\alr-1, Cele\pax-2, Cele\ceh-45, Cele\pax-1, Cele\vab-3, Cele\alp-1" "Xtro\pax8, Xtro\pax5, Xtro\gsc, Xtro\pax1, Xtro\shox2, Xtro\pitx1, Xtro\pax7, Xtro\pax6, Xtro\pax3, Xtro\pax2, Xtro\sia1, Xtro\pdlim5, Xtro\lhx8, Xtro\pitx3, Xtro\arx, Xtro\hoxb8, Xtro\mix1, Xtro\mixer, Xtro\pax9, Xtro\bix1.1" "Mmus\Pax2, Mmus\Pdlim5, Mmus\Dmbx1, Mmus\Pax5, Mmus\Pax4, Mmus\Pax6, Mmus\Pdlim3, Mmus\Pax7, Mmus\Lhx6, Mmus\Cphx3, Mmus\Pax8, Mmus\Gsc, Mmus\Duxbl3, Mmus\Ldb3, Mmus\Cphx1, Mmus\Lhx8, Mmus\Pax9, Mmus\Arx, Mmus\Pdlim7, Mmus\Duxbl2, Mmus\Pitx3, Mmus\Pax3, Mmus\Mixl1, Mmus\Gsc2, Mmus\Shox2, Mmus\Pdlim1, Mmus\Duxbl1, Mmus\Pitx1, Mmus\Pax1" "Hsap\PITX3, Hsap\PAX6, Hsap\SHOX, Hsap\LPXN, Hsap\PDLIM3, Hsap\HOXB8, Hsap\LDB3, Hsap\LHX8, Hsap\SHOX2, Hsap\DUXA, Hsap\PAX5, Hsap\PDLIM1, Hsap\PAX9, Hsap\PDLIM7, Hsap\DUX4, Hsap\DMBX1, Hsap\GSC, Hsap\PAX3, Hsap\GSC2, Hsap\ARX, Hsap\PITX1, Hsap\PAX8, Hsap\PAX7, Hsap\PAX1, Hsap\PAX2, Hsap\MIXL1, Hsap\LHX6, Hsap\PAX4" " embryonic stage | stage 9-11 , pupal stage , embryonic stage , embryonic stage -- adult stage , embryonic stage | stage 9-10 , larval stage | third instar , embryonic stage | stage 12 , adult stage , embryonic stage | stage 16-17 " " tritocerebral neuroblast | subset

, eye-antennal disc | primordium

, protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic ocular segment | restricted

, eye-antennal disc | anterior

, Bolwig's organ

, procephalic neurogenic region && embryonic antennal segment | restricted

, adult head

, deuterocerebral neuroblast | subset

, procephalic neurogenic region && embryonic intercalary segment | restricted

, embryonic central nervous system

" " embryonic stage | stage 9-11 , embryonic stage | stage 9-10 " " procephalic neurogenic region && embryonic intercalary segment | restricted

, protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic antennal segment | restricted

, deuterocerebral neuroblast | subset

, procephalic neurogenic region && embryonic ocular segment | restricted

, tritocerebral neuroblast | subset

" "viable,increased cell death,lethal,partially,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,lethal - all die before end of P-stage,some die during pharate adult stage,neuroanatomy defective,locomotor behavior defective,small body,decreased cell size,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,eye color defective" "neuropil & mushroom body & pupa,ellipsoid body,adult mushroom body,eye,ectopic,antenna,eye disc,eye-antennal disc,ommatidium,medial branch of mushroom body,optic lobe,retina,Kenyon cell,medulla,somatic clone,embryonic/larval optic lobe,adult head,head,heat sensitive,gena,vibrissae,anterior vertical bristle,posterior vertical bristle,photoreceptor cell,lamina anlage glial cell,subretinal glial cell,adult central complex,adult brain,lamina,cell body rind of medulla,serpentine layer,lobula,lobula plate,fan-shaped body,protocerebral bridge,mushroom body & neuron,lobe system of adult mushroom body,calyx of adult mushroom body,wing,adult pars intercerebralis,median bundle,neurite,maxillary palpus,third segment of antenna,arista,embryonic/larval hemolymph,eye | pharate adult stage,wing disc,wing hinge,antennal disc & eye | ectopicdpp.blk1,ventral thoracic disc & eye | ectopicdpp.blk1,proboscis & ommatidium | ectopicdpp.blk1,haltere & ommatidium | ectopicdpp.blk1,leg,proximal,haltere,leg & eye | ectopicdpp.blk1,eye photoreceptor cell | ectopic & antennal discdpp.blk1,eye photoreceptor cell & dorsal mesothoracic disc | ectopicdpp.blk1,eye photoreceptor cell & ventral thoracic disc | ectopicdpp.blk1,photoreceptor,ectopic | third instar larval stage,wing & eye | ectopicupd-E132,leg & eye | ectopicupd-E132,antenna & eye | ectopicupd-E132,haltere & eye | ectopicupd-E132,posterior,anterior/posterior compartment boundary,tibia,head bristle,neuron,haltere disc,ventral thoracic disc,wing & eye | ectopicMS941,vertical branch of mushroom body,vertical lobe of adult mushroom body,ventral nerve cord,commissure,longitudinal connective,intersegmental nerve,segmental nerve,glial cell,embryonic brain,embryonic central brain neuron,tritocerebral commissure,circumesophageal tract,rhabdomerelz-gal4" FBgn0015279 Pi3K92E Pi3K92E http://flybase.org/reports/FBgn0015279 FBgn0014938 protein_coding_gene "phosphatidylinositol-4,5-bisphosphate 3-kinase activity ; GO:0046934 | inferred from sequence or structural similarity with HGNC:8975 1-phosphatidylinositol-3-kinase activity ; GO:0016303 | inferred from sequence or structural similarity with HGNC:8975 1-phosphatidylinositol-3-kinase activity ; GO:0016303 | non-traceable author statement lipid kinase activity ; GO:0001727 | inferred from direct assay phosphatidylinositol-4,5-bisphosphate 3-kinase activity ; GO:0046934 | inferred from direct assay phosphatidylinositol 3-kinase activity ; GO:0035004 | inferred from sequence or structural similarity with HGNC:8975 inferred from sequence or structural similarity with HGNC:8976 inferred from sequence or structural similarity with HGNC:8977 1-phosphatidylinositol-4-phosphate 3-kinase activity ; GO:0035005 | inferred from sequence or structural similarity with HGNC:8975 SH3 domain binding ; GO:0017124 | inferred from physical interaction with drk 1-phosphatidylinositol-4-phosphate 3-kinase activity ; GO:0035005 | inferred from direct assay 1-phosphatidylinositol-3-kinase activity ; GO:0016303 | inferred from direct assay" phosphatidylinositol-mediated signaling=0048015 |... electronic annotation with InterPro:IPR015433 <> regulation of multicellular organism growth=0040014 |... mutant phenotype <> oogenesis=0048477 |... mutant phenotype <> cellular response to starvation=0009267 |... mutant phenotype <> insulin receptor signaling pathway=0008286 | traceable author statement <> regulation of cell size=0008361 | <> positive regulation of cell size=0045793 |... mutant phenotype <> metamorphosis=0007552 |... mutant phenotype <> synapse maturation=0060074 |... direct assay <> positive regulation of organ growth=0046622 | <> larval salivary gland morphogenesis=0007436 |... mutant phenotype <> regulation of cell proliferation=0042127 |... mutant phenotype <> germ-band shortening=0007390 |... mutant phenotype <> regulation of long-term neuronal synaptic plasticity=0048169 |... direct assay <> phosphorylation=0016310 | <> regulation of glucose metabolic process=0010906 |... mutant phenotype <> phosphatidylinositol phosphorylation=0046854 |... sequence or structural similarity with HGNC:8975 <> cell growth=0016049 | traceable author statement <> regulation of lipid storage=0010883 |... mutant phenotype <> negative regulation of autophagy=0010507 |... mutant phenotype <> larval feeding behavior=0030536 |... mutant phenotype <> instar larval development=0002168 |... mutant phenotype <> regulation of multicellular organism growth=0040014 | <> cell competition in a multicellular organism=0035212 |... mutant phenotype <> positive regulation of organ growth=0046622 |... mutant phenotype <> positive regulation of translation=0045727 |... mutant phenotype <> multicellular organism growth=0035264 |... mutant phenotype <> synaptic growth at neuromuscular junction=0051124 |... mutant phenotype <> positive regulation of cell growth=0030307 | <> phosphatidylinositol phosphorylation=0046854 | traceable author statement <> regulation of mitotic cell cycle=0007346 |... mutant phenotype <> lipid metabolic process=0006629 |... mutant phenotype <> autophagy=0006914 |... mutant phenotype <> positive regulation of imaginal disc growth=0045572 |... mutant phenotype <> negative regulation of epidermal growth factor receptor signaling pathway=0042059 |... genetic interaction with Egfr inferred from genetic interaction with aos <> positive regulation of growth=0045927 | traceable author statement <> regulation of dendrite development=0050773 |... mutant phenotype <> phosphatidylinositol phosphorylation=0046854 |... direct assay <> regulation of organ growth=0046620 | <> regulation of reactive oxygen species metabolic process=2000377 |... genetic interaction with InR <> response to oxidative stress=0006979 |... mutant phenotype <> regulation of cell size=0008361 |... mutant phenotype <> insulin receptor signaling pathway=0008286 | <> positive regulation of cell size=0045793 | traceable author statement <> entry into diapause=0055115 |... mutant phenotype <> neuron remodeling=0016322 |... mutant phenotype <> carbohydrate metabolic process=0005975 |... mutant phenotype <> larval development=0002164 |... mutant phenotype <> positive regulation of cell growth=0030307 | traceable author statement <> regulation of synapse structural plasticity=0051823 |... mutant phenotype <> dendrite morphogenesis=0048813 |... direct assay <> intestinal stem cell homeostasis=0036335 |... genetic interaction with mir-305 <> ovarian follicle cell development=0030707 |... mutant phenotype "phosphatidylinositol 3-kinase complex, class IA ; GO:0005943 | non-traceable author statement phosphatidylinositol 3-kinase complex, class IA ; GO:0005943 | inferred from physical interaction with Pi3K21B plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000005674" "PI3K92E, Dp110, PI3K, p110, dp110, dPI3K, type-1 PI3K, Dp110/PI3K, PI-3-K, Pi3Kp110, PI(3)K, CG4141, PI3K-92E/Dp110, p120, PI3K-92D, Dmp110, rea, anon-92Ed, Pi3K92D, Pi3K92E, Pi3K, PI3K-Dp110, dP110, PiK92E, PI-3 kinase, PI3K-dp110, PI[[3]]K, PI3'K, PI3k, DP110, Pi3k, Pi3K92E|p110, dp110alpha, dPI3K[92E], Dpp110, dP13K, pi3k92e, pi3k, PI3K-I, Pi3k92e, dp60" "IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR000341:Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR001263:Phosphoinositide 3-kinase, accessory (PIK) domain, IPR002420:Phosphatidylinositol 3-kinase, C2 domain, IPR003113:Phosphatidylinositol 3-kinase adaptor-binding (PI3K ABD) domain, IPR011009:Protein kinase-like domain, IPR015433:Phosphatidylinositol kinase, IPR016024:Armadillo-type fold, IPR000008:C2 domain, IPR029071:Ubiquitin-related domain" CG4141 11-Aug-17 DroID_v2017_08 "Drer\pik3cd, Drer\pik3cb, Drer\si:rp71-17i16.5, Drer\pik3ca, Drer\zgc:158659, Drer\pik3cg" Scer\VPS34 "Cele\age-1, Cele\piki-1" "Xtro\pik3ca, Xtro\pik3cg, Xtro\pik3cb" "Mmus\Pik3cg, Mmus\Pik3ca, Mmus\Pik3cb, Mmus\Pik3cd" "Hsap\PIK3CB, Hsap\PIK3CD, Hsap\PIK3CA, Hsap\PIK3CG" "wild-type,small body,somatic clone,lethal,viable,recessive,planar polarity defective,decreased cell size,neurophysiology defective,visible,chemical resistant,heat sensitive,neuroanatomy defective,size defective,decreased cell number,cell autonomous,cell non-autonomous,large body,cell size defective,developmental rate defective,increased cell number,wound healing defective,locomotor behavior defective,cell death defective,smell perception defective,long lived,RU486 conditional,semi-sterile,short lived,chemical sensitive,increased cell growth,increased cell size,hyperplasia,feeding behavior defective,cell growth defective,stress response defective,fertile,partially lethal - majority die,some die during pupal stage,some die during larval stage,photoperiod response variant,decreased cell death,starvation stress response defective,decreased cell growth,female sterile" "egg chamber,germline clone,fat body,larva,imaginal disc,ommatidium,somatic clone,embryo,embryonic leading edge cell,head capsule,wing,embryonic/larval neuromuscular junction | third instar larval stage,wing blade,embryonic/larval neuroblast,dorsal multidendritic neuron ddaC | pupal stage,dendrite | larval stageppk.PG,1st posterior cell,eye,synapse,chaeta,mesothoracic tergum,wing & celldpp.blk1,prothoracic gland,wing disc,posterior compartment,imaginal disc & cell,germ band,neuron,supernumerary,embryonic/first instar larval cuticle,antennal lobe,synapseGH298,intrinsic neuron,synapsekra-krasavietz,antennal lobe glomerulus DM2,synapseGH298, kra-krasavietz,synapseMef2.247,adult mushroom body,synapseD42,axonD42,motor neuron,bouton,synapseC57,adult gut,heat sensitive,RU486 conditional,interommatidial bristle,somatic clone | third instar larval stage,embryonic/larval fat body,embryo | dorsal closure stage,embryonic/larval peripheral nervous system | third instar larval stage,plasmatocyte,ectopic,mitotic cell cycle | somatic clone,ommatidial precursor cluster,eye disc,embryonic/larval digestive system,embryonic/larval Malpighian tubule,embryonic/larval epidermis,cell surface & nurse cell | somatic clone,posterior,ring canal,embryonic/larval salivary gland,puparium,lysosomeLsp2.PH,autophagic vacuoleLsp2.PH,ellipsoid body,synapse | supernumerary796,dendrite796,embryonic/larval neuromuscular junction,synapse | supernumeraryD42,dendritesmid-C161,cell bodysmid-C161,dorsal multidendritic neuron ddaC,neuropil,dendrite | somatic cloneVGlut-OK371,cell body | somatic cloneVGlut-OK371,gastric caecum,embryonic/larval fat body | third instar larval stage,autolysosome | third instar larval stage,embryonic/larval gut | third instar larval stage,ovary" FBgn0032901 sky skywalker http://flybase.org/reports/FBgn0032901 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 negative regulation of synaptic vesicle recycling ; GO:1903422 | inferred from mutant phenotype neuron projection development ; GO:0031175 | inferred from sequence or structural similarity with UniProtKB:Q9ULP9 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9ULP9 terminal bouton ; GO:0043195 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay "CG9340, CG14399, anon-WO0118547.455, CG9339, sky" "IPR000195:Rab-GTPase-TBC domain, IPR006571:TLDc domain" CG9339 11-Aug-17 DroID_v2017_08 Drer\tbc1d24 Scer\OXR1 Cele\tbc-7 "Xtro\tbc1d24.2, Xtro\tbc1d24.1" Mmus\Tbc1d24 "Hsap\OXR1, Hsap\TBC1D24" "some die during pupal stage,neurophysiology defective,lethal - all die before end of pupal stage,lethal,uncoordinated,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable" "embryonic/larval neuromuscular junction,neuromuscular junction" DRSC03215 IE -0.666370575 1.587509982 -1.63347697 2.520195685 0.130835993 -0.00250038 FBgn0027633 ms(1)280 ms(1)280 http://flybase.org/reports/FBgn0027633 - gene - - - ms(1)280 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0260591 2L3298 - http://flybase.org/reports/FBgn0260591 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3298 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0050325 CG30325 - http://flybase.org/reports/FBgn0050325 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30325 - CG30325 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036126 Irbp18 Inverted repeat binding protein 18 kDa http://flybase.org/reports/FBgn0036126 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR031106 P-element binding ; GO:0003693 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR004827 double-strand break repair ; GO:0006302 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" DNA repair complex ; GO:1990391 | inferred from direct assay "CT19628, BcDNA:GH10915, Irbp18, CG6272, DM10, IRBP18" IPR004827:Basic-leucine zipper domain CG6272 11-Aug-17 DroID_v2017_08 "Drer\hlfb, Drer\nfil3-4, Drer\cebp1, Drer\hlfa, Drer\dbpa, Drer\dbpb, Drer\cebpd, Drer\ddit3, Drer\cebpg, Drer\nfil3-2, Drer\si:dkey-172o19.2, Drer\nfil3-5, Drer\cebpa, Drer\cebpb" - "Cele\zip-2, Cele\cebp-2, Cele\zip-4" "Xtro\cebpa, Xtro\cebpg, Xtro\hlf, Xtro\cebpb" "Mmus\Cebpb, Mmus\Cebpa, Mmus\Tef, Mmus\Cebpe, Mmus\Hlf, Mmus\Cebpg, Mmus\Cebpd" "Hsap\CEBPB, Hsap\TEF, Hsap\CEBPG, Hsap\DBP, Hsap\HLF, Hsap\CEBPA, Hsap\CEBPD, Hsap\CEBPE" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC10612 E -0.239751538 0.212987481 -0.145804849 1.8747706 -0.990761968 1.115964596 FBgn0014007 Ptp69D Protein tyrosine phosphatase 69D http://flybase.org/reports/FBgn0014007 - protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement transmembrane receptor protein tyrosine phosphatase activity ; GO:0005001 | inferred from sequence or structural similarity "motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Ptp4E, Ptp10D protein dephosphorylation ; GO:0006470 | inferred from direct assay defasciculation of motor neuron axon ; GO:0007415 | inferred from mutant phenotype inferred from genetic interaction with Ptp99A axonal defasciculation ; GO:0007414 | traceable author statement protein dephosphorylation ; GO:0006470 | non-traceable author statement axon guidance ; GO:0007411 | inferred from genetic interaction with sas inferred from genetic interaction with Ptp10D motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Ptp10D dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype inferred from genetic interaction with Ptp99A fasciculation of sensory neuron axon ; GO:0097155 | inferred from mutant phenotype axon guidance ; GO:0007411 | non-traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity cell surface ; GO:0009986 | "DPTP69D, PTP69D, dptp69D, Ptp69d, Dptp69D, PTPase, CT30751, R-PTP 69D, CG10975, ptp69D, DPTP, Ptp, Ptp69D, dptp69d, ptp69d, 69D, RPtp69D" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR003595:Protein-tyrosine phosphatase, catalytic" CG10975 11-Aug-17 DroID_v2017_08 "Drer\ptprdb, Drer\ptprq, Drer\ptprsa, Drer\ptprz1b, Drer\ptprea, Drer\ptpreb, Drer\ptprfa, Drer\ptprk, Drer\si:ch1073-391i24.1, Drer\ptpra, Drer\ptpn23a, Drer\ptprt, Drer\ptprua, Drer\ptprub, Drer\ptprfb, Drer\ptprc, Drer\LOC101884960, Drer\ptprd" "Scer\PTP3, Scer\PTP1, Scer\PTP2" Cele\clr-1 "Xtro\ptprs, Xtro\ptpru, Xtro\ptprf, Xtro\ptpre, Xtro\ptpra, Xtro\ptprd, Xtro\ptprm, Xtro\ptprk, Xtro\ptprc" "Mmus\Ptprz1, Mmus\Ptprf, Mmus\Ptpru, Mmus\Ptprd, Mmus\Ptpre, Mmus\Ptprs, Mmus\Ptprm, Mmus\Ptpra, Mmus\Ptprk, Mmus\Ptprq, Mmus\Ptprt, Mmus\Ptprc" "Hsap\PTPRA, Hsap\PTPRM, Hsap\PTPRC, Hsap\PTPRU, Hsap\PTPRT, Hsap\PTPRS, Hsap\PTPRE, Hsap\PTPRF, Hsap\PTPRD, Hsap\PTPRK, Hsap\PTPRQ, Hsap\PTPRZ1" larval stage | third instar " lamina plexus | anterior

, medulla neuropil

, lamina neuropil

, larval optic neuropil

" "neuroanatomy defective,wild-type,lethal,partially,heat sensitive,viable,recessive,lethal - all die before end of pupal stage,some die during pupal stage,planar polarity defective,body color defective,visible" "dendritic arborizing neuron,axon,dendrite,photoreceptor cell & axon | somatic clone,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,medulla,somatic clone,RP neuron & axon,central nervous system,abdominal segmental nerve,intersegmental nerve,RP1 motor neuron,RP3 motor neuron,RP4 motor neuron,RP5 motor neuron,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina plexus,glial cell & lamina,mesothoracic tergum,chaeta,supernumerary" DRSC11258 K 1.101237795 -0.227048802 1.034879981 -0.472699704 3.452830469 0.743735015 FBgn0051774 fred friend of echinoid http://flybase.org/reports/FBgn0051774 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory organ development ; GO:0007423 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype inferred from genetic interaction with pnt inferred from genetic interaction with Vang inferred from genetic interaction with stan inferred from genetic interaction with cno adult chitin-based cuticle pattern formation ; GO:0035018 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CT11413, CG3393, CG3390, CG12675, CG31774, fred, Fred" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013162:CD80-like, immunoglobulin C2-set" CG31774 11-Aug-17 DroID_v2017_08 "Drer\kirrel3b, Drer\tmigd1, Drer\kirrel3l, Drer\kirrela, Drer\fpgs, Drer\kirrelb, Drer\nphs1, Drer\kirrel3a" "Scer\FOL3, Scer\RMA1, Scer\MET7" "Cele\igcm-1, Cele\F22D3.6" "Xtro\nphs1, Xtro\fpgs" "Mmus\Kirrel3, Mmus\Kirrel, Mmus\Kirrel2, Mmus\Malt1, Mmus\Nphs1, Mmus\Fpgs" "Hsap\MALT1, Hsap\NPHS1, Hsap\KIRREL3, Hsap\KIRREL2, Hsap\KIRREL, Hsap\FPGS" " embryonic stage , larval stage | third instar " " organism

, eye disc

ubiquitous , dorsal mesothoracic disc

ubiquitous " "increased cell death,viable" "ommatidium,somatic clone,ommatidial precursor cluster,adult cuticle,mesothoracic tergum,scutellum,macrochaeta,ectopic,dorsal mesothoracic disc & sensory mother cell | dorsal | ectopicpnr-MD237,eye,dorsal mesothoracic disc & sensory mother cell | ectopicap-md544" FBgn0001320 kni knirps http://flybase.org/reports/FBgn0001320 "FBgn0003253, FBgn0017615" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 protein binding ; GO:0005515 | inferred from physical interaction with gro repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with CtBP transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay" "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype inferred from genetic interaction with gro dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype epidermis development ; GO:0008544 | inferred from mutant phenotype branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement regulation of tube size, open tracheal system ; GO:0035151 | traceable author statement zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement trunk segmentation ; GO:0035290 | traceable author statement zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | non-traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001628 "Kni, CG4717, ri, KNI, NR0A1, kn, kni, KNIRPS, Kn, knr" "IPR001628:Zinc finger, nuclear hormone receptor-type, IPR013088:Zinc finger, NHR/GATA-type" CG4717 11-Aug-17 DroID_v2017_08 - - "Cele\nhr-85, Cele\nhr-179, Cele\nhr-7, Cele\nhr-119, Cele\nhr-23, Cele\nhr-3" - Mmus\Rora Hsap\RORA " embryonic stage | cellular blastoderm , embryonic stage | stage 4 , embryonic stage , embryonic stage | early , larval stage | third instar , embryonic stage | blastoderm " "

30-50% egg length ,

20-40% egg length ,

anterior , wing vein L2 | precursor

,

70-100% egg length , organism | 30-50% egg length

" "viable,fertile,wild-type,visible,heat sensitive,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,embryonic/larval segmentation phenotype,dominant,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal branch primordium,wing vein,heat sensitive,wing,ectopic,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,abdomen,wing vein L2,mesothoracic ventral denticle belt,mesothoracic segment,ventral,distal,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,extended germ band embryo,embryonic/first instar larval cuticle & abdominal segment 1,embryonic/first instar larval cuticle & abdominal segment 2,embryonic/first instar larval cuticle & abdominal segment 3,embryonic/first instar larval cuticle & abdominal segment 4,embryonic/first instar larval cuticle & abdominal segment 5,embryonic/first instar larval cuticle & abdominal segment 6,embryonic/first instar larval cuticle & abdominal segment 7,macrophage,embryo,abdominal segment,embryonic/larval dorsal anastomosis,adherens junction & embryonic dorsal trunkbtl.PS,dorsal trunk primordium,metathoracic femur,adult thorax & macrochaetaBx-MS1096" FBgn0001083 fw furrowed http://flybase.org/reports/FBgn0001083 - protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay apical junction complex ; GO:0043296 | inferred from direct assay "fw-like, CT3745, wr, CG1500, fw" "IPR018378:C-type lectin, conserved site, IPR000421:Coagulation factor 5/8 C-terminal domain, IPR000436:Sushi/SCR/CCP domain, IPR001304:C-type lectin-like, IPR006585:Fucolectin tachylectin-4 pentraxin-1, IPR008979:Galactose-binding domain-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG1500 11-Aug-17 DroID_v2017_08 "Drer\cfhl2, Drer\cfhl1, Drer\selp, Drer\im:7151449, Drer\susd4, Drer\si:ch211-233f16.1, Drer\cfh, Drer\csmd2, Drer\sele, Drer\si:ch211-236p22.1" - "Cele\lev-9, Cele\T07H6.4, Cele\C54G4.4" "Xtro\cfh, Xtro\selp, Xtro\f13b" "Mmus\Sell, Mmus\Selp, Mmus\Csmd3, Mmus\Cfhr1, Mmus\Sele, Mmus\Cr1l, Mmus\Gm4788, Mmus\Cfh, Mmus\Susd4, Mmus\Svep1, Mmus\Cfhr2, Mmus\Cd46, Mmus\F13b, Mmus\Csmd1" "Hsap\CFHR2, Hsap\C4BPB, Hsap\CFHR4, Hsap\CSMD2, Hsap\CSMD3, Hsap\CFHR3, Hsap\CSMD1, Hsap\CD46, Hsap\F13B, Hsap\CFH, Hsap\SVEP1, Hsap\SELE, Hsap\SELL, Hsap\CFHR5, Hsap\SUSD4, Hsap\SELP, Hsap\CFHR1" " larval stage | first instar -- larval stage | third instar , embryonic stage -- adult stage " " larval brain | restricted

, embryonic/larval proventriculus | restricted

" larval stage | first instar -- larval stage | third instar " larval brain | restricted

, embryonic/larval proventriculus | restricted

" "viable,visible,lethal,partially,female,planar polarity defective,somatic clone,fertile,wild-type,male fertile,female fertile,male,reduced,eye color defective,sterile,female sterile,recessive,poor,partially lethal - majority live,partially lethal - majority die,some die during pupal stage" "eye,adult head,scutellum,notopleural bristle,macrochaeta,posterior scutellar bristle,retina,ommatidium,interommatidial bristle,microchaeta,eye & macrochaeta,lamina,eye photoreceptor cell,cone cell,pigment cell,chaeta,trichome,wing hair,mesothoracic tergum,scutellar bristle,postalar bristle,wing,arista,scutoscutellar suture,embryonic/larval anal pad,pupal spiracle,ovariole,testis sheath,Malpighian tubule,acrostichal bristle,wing vein,trichogen cell" FBgn0003158 ptg pentagon http://flybase.org/reports/FBgn0003158 - gene - oogenesis ; GO:0048477 | traceable author statement - "3D18, fs(1)M71, cro, ptg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,recessive,lethal,visible,female sterile,partially,body color defective" "trident,scutellum" FBgn0260015 trin trinidad http://flybase.org/reports/FBgn0260015 gene - karyosome formation ; GO:0030717 | inferred from mutant phenotype - trin - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "karyosome,chorion | germline clone" FBgn0014135 bnl branchless http://flybase.org/reports/FBgn0014135 "FBgn0010906, FBgn0013633" protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR002209 fibroblast growth factor receptor binding ; GO:0005104 | traceable author statement "cytoneme assembly ; GO:0035231 | inferred from direct assay positive chemotaxis ; GO:0050918 | traceable author statement genital disc development ; GO:0035215 | inferred from expression pattern epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement open tracheal system development ; GO:0007424 | non-traceable author statement terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | traceable author statement primary branching, open tracheal system ; GO:0007428 | traceable author statement morphogenesis of a branching structure ; GO:0001763 | traceable author statement glial cell migration ; GO:0008347 | inferred from mutant phenotype regulation of tube architecture, open tracheal system ; GO:0035152 | traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement open tracheal system development ; GO:0007424 | traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement filopodium assembly ; GO:0046847 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | non-traceable author statement secondary branching, open tracheal system ; GO:0007429 | traceable author statement chemotaxis ; GO:0006935 | traceable author statement activation of MAPK activity ; GO:0000187 | inferred from expression pattern" extracellular region ; GO:0005576 | inferred from sequence or structural similarity "FGF, Bnl, l(3)06916, DFGF, l(3)neo52, CG4608, bnl, DmBnl, BNL, dFGF" "IPR002209:Fibroblast growth factor family, IPR008996:Cytokine IL1/FGF" CG4608 11-Aug-17 DroID_v2017_08 "Drer\fgf6b, Drer\fgf13b, Drer\fgf8a, Drer\fgf19, Drer\fgf5, Drer\fgf4, Drer\fgf11b, Drer\fgf20a, Drer\fgf8b, Drer\fgf1a, Drer\fgf2, Drer\fgf22, Drer\fgf12a, Drer\fgf18a, Drer\fgf24, Drer\fgf13a, Drer\fgf3, Drer\fgf10a, Drer\fgf21, Drer\fgf12b, Drer\fgf16, Drer\fgf7, Drer\fgf18b, Drer\fgf9, Drer\fgf1b, Drer\fgf17, Drer\fgf14, Drer\fgf10b, Drer\fgf23, Drer\fgf11a, Drer\fgf6a, Drer\fgf20b" - Cele\let-756 "Xtro\fgf19, Xtro\fgf6, Xtro\fgf1, Xtro\fgf20, Xtro\fgf14, Xtro\fgf9, Xtro\fgf23.2, Xtro\fgf3, Xtro\fgf2, Xtro\fgf5, Xtro\fgf10, Xtro\fgf7, Xtro\fgf8, Xtro\fgf13, Xtro\fgf16, Xtro\fgf4, Xtro\fgf12" "Mmus\Fgf7, Mmus\Fgf6, Mmus\Fgf20, Mmus\Fgf16, Mmus\Fgf13, Mmus\Fgf4, Mmus\Fgf2, Mmus\Fgf8, Mmus\Fgf15, Mmus\Fgf22, Mmus\Fgf14, Mmus\Fgf3, Mmus\Fgf23, Mmus\Fgf5, Mmus\Fgf9, Mmus\Fgf11, Mmus\Fgf12, Mmus\Fgf17, Mmus\Fgf10, Mmus\Fgf21, Mmus\Fgf18, Mmus\Fgf1" "Hsap\FGF2, Hsap\FGF16, Hsap\FGF5, Hsap\FGF12, Hsap\FGF17, Hsap\FGF11, Hsap\FGF13, Hsap\FGF19, Hsap\FGF10, Hsap\FGF3, Hsap\FGF4, Hsap\FGF14, Hsap\FGF6, Hsap\FGF22, Hsap\FGF7, Hsap\FGF21, Hsap\FGF8, Hsap\FGF9, Hsap\FGF20, Hsap\FGF18, Hsap\FGF23, Hsap\FGF1" " embryonic stage , embryonic stage | stage >=11 , larval stage | third instar " " cephalic furrow

, posterior transverse furrow

, tracheal air sac | surrounding

, dorsal mesothoracic disc | anterior/posterior compartment boundary & vicinity of & dorsal & restricted

" "lethal,recessive,cell migration defective,visible,somatic clone,cell adhesion defective,hyperplasia,heat sensitive,viable" "embryonic/larval tracheal system,air sac tracheoblast of dorsal air sac primordium,cell non-autonomous,somatic clone,embryonic/larval trachea,lateral H branch,lateral G branch,embryonic/larval ganglionic branch,presumptive embryonic/larval tracheal system,tracheal metamere 1,tracheal metamere 2,tracheal metamere 3,tracheal metamere 4,tracheal metamere 5,tracheal metamere 6,tracheal metamere 7,tracheal metamere 8,tracheal metamere 9,tracheal metamere 10,ganglionic branch primordium,embryonic/larval dorsal trunk,eye,subretinal glial cell,ommatidium,actin cytoskeleton | pupal stage | somatic clone,tracheal system,air sac tracheoblast of dorsal mesothoracic disc & filopodium,dorsal air sac primordium,heat sensitive,air sac tracheoblast of dorsal mesothoracic disc & filopodium | somatic clone | cell non-autonomous,trachea,embryonic tracheal system & filopodium | ectopicbtl.PS,embryonic/larval dorsal branch,embryonic/larval lateral trunk,visceral branch,tracheal tip cell | embryonic stage,pupal abdominal trachea,tracheal metamere" FBgn0030057 Ppt1 Palmitoyl-protein thioesterase 1 http://flybase.org/reports/FBgn0030057 protein_coding_gene palmitoyl-(protein) hydrolase activity ; GO:0008474 | inferred from mutant phenotype palmitoyl hydrolase activity ; GO:0098599 | inferred from direct assay palmitoyl-(protein) hydrolase activity ; GO:0008474 | inferred from sequence or structural similarity with MGI:MGI:1298204 inferred from mutant phenotype palmitoyl-(protein) hydrolase activity ; GO:0008474 | inferred from direct assay protein depalmitoylation ; GO:0002084 | inferred from mutant phenotype positive regulation of synaptic vesicle endocytosis ; GO:1900244 | inferred from mutant phenotype macromolecule depalmitoylation ; GO:0098734 | inferred from direct assay endocytosis ; GO:0006897 | inferred from direct assay regulation of axon guidance ; GO:1902667 | inferred from mutant phenotype neuron fate specification ; GO:0048665 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype lysosome ; GO:0005764 | inferred from sequence or structural similarity with MGI:MGI:1298204 lysosome ; GO:0005764 | inferred from direct assay "DmPpt1, CG12108, PPT1, Ppt1, ppt1" "IPR002472:Palmitoyl protein thioesterase, IPR030294:Palmitoyl-protein thioesterase 1, IPR029058:Alpha/Beta hydrolase fold" CG12108 11-Aug-17 DroID_v2017_08 "Drer\zgc:55413, Drer\ppt1, Drer\ppt2, Drer\zgc:77118, Drer\zgc:55621, Drer\zgc:66024" Scer\CAX4 Cele\ppt-1 "Xtro\ppt1, Xtro\ppt2" "Mmus\Dolpp1, Mmus\Ppt2, Mmus\Ppt1" "Hsap\PPT2, Hsap\DOLPP1, Hsap\PPT1" " adult stage , embryonic stage | 0-18hr , larval stage | third instar , pupal stage , " " adult thorax

, adult head

, testis

, ovary

,

" " larval stage | third instar , pupal stage , adult stage , , embryonic stage | 0-18hr " " adult head

, testis

, adult thorax

,

, ovary

" "lethal,partially,visible,increased cell death,neuroanatomy defective,short lived,recessive,locomotor behavior defective,neurophysiology defective,endocytosis defective,viable" "rhabdomere of eye photoreceptor cell,eye,eye photoreceptor cell,ommatidium,adult brain,ganglion mother cell GMC4-2a,RP2 motor neuron,RP2sib neuron,aCC neuron,supernumerary,pCC neuron,longitudinal connective,midline neuron,ectopic,lch5 neuron,embryonic/larval neuromuscular junction,garland cell" FBgn0001291 Jra Jun-related antigen http://flybase.org/reports/FBgn0001291 "FBgn0002124, FBgn0015487, FBgn0017591, FBgn0023037" protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A8MPH9 protein binding ; GO:0005515 | inferred from physical interaction with chm RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000894784 protein binding ; GO:0005515 | inferred from physical interaction with Atf3 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 protein binding ; GO:0005515 | inferred from physical interaction with Cka RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay transcription factor binding ; GO:0008134 | traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with kay" "response to drug ; GO:0042493 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 multicellular organism aging ; GO:0010259 | inferred from mutant phenotype micropyle formation ; GO:0046844 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype positive regulation of cell differentiation ; GO:0045597 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 response to cAMP ; GO:0051591 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000894784 response to lipopolysaccharide ; GO:0032496 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 JNK cascade ; GO:0007254 | traceable author statement dorsal closure ; GO:0007391 | non-traceable author statement regulation of cell death ; GO:0010941 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype R7 cell fate commitment ; GO:0007465 | traceable author statement response to radiation ; GO:0009314 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay response to cytokine ; GO:0034097 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 MAPK cascade ; GO:0000165 | traceable author statement response to mechanical stimulus ; GO:0009612 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 negative regulation of antimicrobial humoral response ; GO:0008348 | inferred from mutant phenotype inferred from genetic interaction with Rel dorsal closure ; GO:0007391 | inferred from mutant phenotype inferred from genetic interaction with bsk R3/R4 cell fate commitment ; GO:0007464 | traceable author statement positive regulation of heart contraction ; GO:0045823 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from genetic interaction with kay wound healing ; GO:0042060 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 establishment of planar polarity ; GO:0001736 | non-traceable author statement cellular response to hormone stimulus ; GO:0032870 | inferred from biological aspect of ancestor with PANTHER:PTN000894785 JNK cascade ; GO:0007254 | inferred from mutant phenotype inferred from genetic interaction with bsk inferred from genetic interaction with hep inferred from genetic interaction with Rac1 imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype" nucleus ; GO:0005634 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000894784 transcription factor complex ; GO:0005667 | inferred from physical interaction with kay nucleus ; GO:0005634 | inferred from direct assay "Jra, jun, Djun, AP-1, Jun, JRA, DJun, DJUN, D-jun, c-Jun, D-Jun, d-Jun, jra, d-jun, AP1, cJun, CG2275, dJRA, dJun, l(2R)IA109, dJUN, l(2)IA109, dm-Jun, dAP-1, d-JRA, dJra, V, l(2)46Ef, D-jun/Jra, djun, JUN, DM14" "IPR002112:Transcription factor Jun, IPR004827:Basic-leucine zipper domain, IPR005643:Jun-like transcription factor, IPR029823:Transcription factor JunD, IPR008917:Transcription factor, Skn-1-like, DNA-binding domain" CG2275 11-Aug-17 DroID_v2017_08 "Drer\zgc:153924, Drer\jund, Drer\junba, Drer\jun, Drer\junbb" Scer\GCN4 Cele\jun-1 "Xtro\jun, Xtro\jund.2, Xtro\jund, Xtro\junb" "Mmus\Atf7, Mmus\Jun, Mmus\Junb, Mmus\Jund" "Hsap\JUND, Hsap\JUNB, Hsap\ATF2, Hsap\JUN, Hsap\ATF7" " embryonic stage , embryonic stage -- adult stage "

ubiquitous " larval stage | third instar , embryonic stage | stage >=12 , embryonic stage " " cone cell

, photoreceptor cell

, morphogenetic furrow | posterior to

, mystery cell

, dorsal ectoderm

, cephalic furrow

, ommatidial precursor cluster

, amnioserosa

" "neurophysiology defective,neuroanatomy defective,somatic clone,visible,dominant,planar polarity defective,wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,lethal - all die before end of prepupal stage,some die during prepupal stage,partially lethal - majority die,some die during pupal stage,hypoactive" "adult heart,RU486 conditional,bouton,neuromuscular junction | larval stage,eye,NMJ bouton,somatic clone,embryonic/larval neuromuscular junction,indirect flight muscle motor neuron MN5,dendriteD42, GAL80Cha.3.3P,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,RP2 motor neuron,eye photoreceptor cell,photoreceptor cell R7,cone cell,ommatidium,ectopic,rhabdomere,supernumerary,photoreceptor cell R4,eye disc,ommatidial precursor cluster,embryonic/first instar larval cuticle,heat sensitive,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R5,photoreceptor cell R6,dorsal,embryonic dorsal epidermis,head,epidermis,embryo,anterior,embryonic epidermis,dorsal appendage,maternal effect,micropyle,dorsal closure embryo,midline primordium,photoreceptor cell,commissure,adult thorax,mesothoracic tergum" DRSC07447 IE 3.841476113 1.989327101 2.622856322 1.513888039 -0.2808174 -1.133893617 FBgn0001614 l(1)dd10 lethal (1) discs degenerate 10 http://flybase.org/reports/FBgn0001614 - gene - - - "l(1)d.deg.-10, l(1)d deg-10, l(1)d.deg.10, l(1)dd10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,cell lethal,germline clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,cell cycle" FBgn0036574 elg1 enhanced level of genomic instability 1 http://flybase.org/reports/FBgn0036574 protein_coding_gene - oogenesis ; GO:0048477 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype Elg1 RFC-like complex ; GO:0031391 | inferred from direct assay "elg1, CG16838" IPR027417:P-loop containing nucleoside triphosphate hydrolase CG16838 11-Aug-17 DroID_v2017_08 "Drer\atad5a, Drer\atad5b" Scer\ELG1 Cele\Y53F4B.9 Xtro\atad5 Mmus\Atad5 Hsap\ATAD5 "female sterile,viable,visible,lethal,neuroanatomy defective" "nurse cell,macrochaeta,germline clone,embryonic/larval neuroblast" FBgn0052573 CG32573 - http://flybase.org/reports/FBgn0052573 protein_coding_gene - - - "CG4524, CG13013, CG32573, Dromel_CG32573_FBtr0074315_mORF" - CG32573 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0005771 noc no ocelli http://flybase.org/reports/FBgn0005771 "FBgn0001971, FBgn0002947" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein binding ; GO:0005515 | inferred from physical interaction with elB "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity leg disc development ; GO:0035218 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from genetic interaction with elB negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype compound eye photoreceptor fate commitment ; GO:0001752 | inferred from genetic interaction with elB open tracheal system development ; GO:0007424 | inferred from mutant phenotype ocellus development ; GO:0008056 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from genetic interaction with elB" nucleus ; GO:0005634 | inferred from sequence or structural similarity "noc, nocA, l(2)35Ba, BG:DS04641.1, l35Ba, l(2)35Ba/nocA, noc[A], el, CG4491, Noc, NocA, br22, l(2)br22" IPR013087:Zinc finger C2H2-type CG4491 11-Aug-17 DroID_v2017_08 "Drer\znf503, Drer\LOC100333111, Drer\znf703" - Cele\tlp-1 "Xtro\znf703, Xtro\znf503" "Mmus\Zfp503, Mmus\Zfp703" "Hsap\ZNF503, Hsap\ZNF703" " embryonic stage | stage 5 , embryonic stage | stage 8-12 , embryonic stage | stage 10-12 , embryonic stage -- adult stage , embryonic stage | stage 5-6 , embryonic stage | stage 8 , embryonic stage | stage 9 " " organism | 90-100% egg length

, labral segment

, stomodeum

, tracheal primordium | surrounding

, ectoderm | stripes

, ventral nerve cord primordium | 50-90% egg length , procephalic segment

, ventral neurogenic region | striped

" "viable,visible,recessive,behavior defective,lethal,lethal - all die before end of larval stage,some die during larval stage" "ocellus,anterior postalar bristle,microchaeta,ocellar bristle,head bristle,postvertical bristle,lateral ocellus,medial ocellus,lateral trunk anterior branch,ganglionic branch primordium,dorsal branch primordium,supraesophageal ganglion,macrochaeta" FBgn0011648 Mad Mothers against dpp http://flybase.org/reports/FBgn0011648 "FBgn0000105, FBgn0013945, FBgn0022270, FBgn0024356" protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V853 RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay RNA polymerase II activating transcription factor binding ; GO:0001102 | inferred from physical interaction with shn DNA binding ; GO:0003677 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Med protein binding ; GO:0005515 | inferred from physical interaction with vis transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ; GO:0030618 | non-traceable author statement RNA polymerase II transcription coactivator activity ; GO:0001105 | inferred from direct assay" negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from expression pattern ovarian follicle cell development ; GO:0030707 | traceable author statement somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype histoblast morphogenesis ; GO:0007488 | inferred from mutant phenotype wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype BMP signaling pathway involved in Malpighian tubule cell chemotaxis ; GO:0061353 | inferred from direct assay dorsal closure ; GO:0007391 | non-traceable author statement trunk segmentation ; GO:0035290 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification ; GO:0060799 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of synapse structure or activity ; GO:0050803 | inferred from direct assay imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | traceable author statement transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from genetic interaction with dpp inferred from genetic interaction with tkv inferred from genetic interaction with wg ventral cord development ; GO:0007419 | inferred from mutant phenotype transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR013019 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement "Mad, mad, pMad, p-Mad, pMAD, MAD, 2/23, l(2)K00237, apg, l(2)k00237, En(vvl), E(zen)2, CG12399, P-mad, P-Mad, dMAD, dMad, PMad, c28, Mat, Smad, pSmad, Smad1" "IPR001132:SMAD domain, Dwarfin-type, IPR003619:MAD homology 1, Dwarfin-type, IPR008984:SMAD/FHA domain, IPR013019:MAD homology, MH1, IPR013790:Dwarfin, IPR017855:SMAD domain-like" CG12399 11-Aug-17 DroID_v2017_08 "Drer\smad9, Drer\smad3a, Drer\smad4a, Drer\smad6b, Drer\smad7, Drer\smad2, Drer\si:dkey-239n17.4, Drer\smad5, Drer\smad6a, Drer\gb:cr929477, Drer\si:dkey-222b8.1, Drer\smad3b, Drer\smad1" "Scer\WHI3, Scer\RIM1" "Cele\daf-14, Cele\gei-4, Cele\sma-2, Cele\daf-8, Cele\sma-3" "Xtro\smad6.2, Xtro\smad2, Xtro\smad9, Xtro\smad6, Xtro\smad4.1, Xtro\smad4.2, Xtro\smad7, Xtro\smad3, Xtro\smad1" "Mmus\Smad7, Mmus\Smad9, Mmus\Smad4, Mmus\Smad2, Mmus\Smad5, Mmus\Smad6, Mmus\Smad3, Mmus\Smad1" "Hsap\SMAD5, Hsap\SMAD9, Hsap\SMAD7, Hsap\SMAD1, Hsap\SMAD6, Hsap\SMAD2, Hsap\SMAD3, Hsap\SMAD4, Hsap\ZNF396" embryonic stage -- adult stage embryonic stage

ubiquitous "visible,recessive,sterile,heat sensitive,short lived,RU486 conditional,lethal,neuroanatomy defective,dominant,neurophysiology defective,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during larval stage,decreased cell number,wild-type,viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female sterile,germline clone,rescuable maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,small body,mitotic cell cycle defective,cell autonomous,size defective,partially lethal - majority live,increased cell death,conditional" "tarsal segment,heat sensitive,tibia,wing vein L4,wing vein L5,abdominal segment,neuromuscular junction,NMJ bouton,wing,embryonic/larval neuromuscular junction,leg,distal,imaginal disc,photoreceptor cell,somatic clone,eye,embryonic/larval fat body,embryonic/larval optic lobe,embryonic/larval midgut,anterior,testis,germline clone,eye disc,posterior,cell non-autonomous,embryonic/larval dorsal branch,wing disc,eye disc | third instar larval stage,eye-antennal disc,morphogenetic furrow,ommatidium,frons,ectopic,wing vein,wing cell,maternal effect,embryonic/first instar larval cuticle,synapse,t-bar,histoblast,histoblast nest,embryonic/larval somatic muscle,bouton,neuromuscular junctionC28),fat body,denticle belt,female germline stem cell,gastric caecum,embryonic/larval tracheal system,embryonic/larval ventral anastomosis,egg,egg chamber,ovariole,crystal cell,pleurum,male germline stem cell,germarium,wing vein L3,cell autonomous,wing vein L2,tergite,interommatidial bristle,secondary pigment cell,tertiary pigment cell,adult midgut precursor cell,wing margin,ventral,posterior crossvein,wing margin bristle,crossvein,neuromuscular junctionMhc.PW,bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage,wing disc | third instar larval stage,anterior wing margin,temperature conditional,dorsal triple row,wing sensillum,medial triple row,supernumerary,wing pouch,ovary,wing blade" FBgn0062658 EP3283 EP3283 http://flybase.org/reports/FBgn0062658 gene - - - "EP(3)3283, EP3283" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing margin bristle,wing vein,supernumerary" FBgn0044826 Pak3 Pak3 http://flybase.org/reports/FBgn0044826 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 Rac GTPase binding ; GO:0048365 | inferred from physical interaction with Rac1 inferred from physical interaction with Rac2 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Pak3" actin filament organization ; GO:0007015 | inferred from genetic interaction with Rac1 protein phosphorylation ; GO:0006468 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of synapse assembly ; GO:0051965 | inferred from genetic interaction with spas protein autophosphorylation ; GO:0046777 | inferred from direct assay actin filament organization ; GO:0007015 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from biological aspect of ancestor with PANTHER:PTN000685295 myoblast fusion ; GO:0007520 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from biological aspect of ancestor with PANTHER:PTN000685295 filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 ruffle ; GO:0001726 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "PaK3, DmPAK3, CG14895, D-Pak3, DPAK3, pak3, dPAK3, PAK3, anon-WO0118547.285, Pak3, DPak3, dpak3, Dpak3, PAK-3" "IPR000095:CRIB domain, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR033923:p21 activated kinase binding domain" CG14895 11-Aug-17 DroID_v2017_08 "Drer\pak4, Drer\LOC100536197, Drer\pak2a, Drer\pak6b, Drer\pak2b, Drer\pak1" "Scer\STE20, Scer\CLA4, Scer\SKM1" "Cele\max-2, Cele\pak-2, Cele\pak-1" "Xtro\pak4, Xtro\pak2, Xtro\pak1, Xtro\pak3, Xtro\pak6, Xtro\pak7" "Mmus\Pak2, Mmus\Pak4, Mmus\Pak7, Mmus\Pak6, Mmus\Pak3, Mmus\Pak1" "Hsap\PAK3, Hsap\PAK5, Hsap\PAK1, Hsap\PAK4, Hsap\PAK6, Hsap\PAK2" "viable,lethal,recessive,neuroanatomy defective,lethal - all die before end of first instar larval stage,lethal - all die before end of larval stage,partially lethal - majority die,partially lethal - majority live,neurophysiology defective,visible" "embryonic/larval cuticle,embryonic myoblast,filamentous actin,embryonic/larval neuromuscular junction,NMJ bouton,microtubuleelav.PU,trichogen cell" DRSC15017 IE 0.490081115 -2.488027712 1.089344813 -1.623929002 -0.376350973 -1.156488887 FBgn0034331 CG15067 - http://flybase.org/reports/FBgn0034331 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "anon-EST:Posey85, CG15067" IPR013172:Immune-induced protein Dim CG15067 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC06502 IE 2.247974115 1.64130564 2.476690802 -0.529705473 -0.049395078 0.079836396 FBgn0026320 Tom Twin of m4 http://flybase.org/reports/FBgn0026320 "FBgn0025249, FBgn0026264" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with neur ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000262353 sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with Su(H) inferred from genetic interaction with Su(H) establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG5185, bbu/tom, Bbu, barbu, anon-EST:fe1F6, Tom, tom, DmelCG5185" IPR029686:Enhancer of split M4 family CG5185 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 14 , P | stage P4 , embryonic stage | stage 4 , larval stage | third instar , embryonic stage | stage 5 , embryonic stage , embryonic stage | stage 9-12 , larval stage | first instar , embryonic stage | stage 7-11 , embryonic stage | stage 9 , embryonic stage | stage 11 " " lymph gland

, sensillum campaniformium &&of wing

, organism | 90-100% egg length

, morphogenetic furrow | vicinity of

, organism | 0-100% egg length & lateral

, organism | 0-100% egg length & dorsal

, morphogenetic furrow | anterior to

, eye disc

, morphogenetic furrow | posterior to

, ectoderm | restricted

, mesoderm

, ventral neurogenic region

, ventral midline

, embryonic/larval tracheal pit | precursor

, organism | 30-70% egg length

" " embryonic stage , embryonic stage | stage 9 , embryonic stage | blastoderm , embryonic stage | stage 14 , embryonic stage | stage 11 " " mesoderm

, ventral midline

, ventral neurogenic region

, ectoderm | restricted

, lymph gland

, embryonic/larval tracheal pit | precursor

" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,planar polarity defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,lethal,neuroanatomy defective,viable" "macrochaeta,adult head,scutellar bristle,scutum & microchaeta,eye,ommatidium,interommatidial bristle,somatic clone,eye photoreceptor cell,central nervous system,peripheral nervous system,embryonic head,dorsocentral bristle,ectopic,scutum & microchaeta | ectopicpnr-MD237,head bristle,lens,microchaeta,microchaeta & leg-537.4,leg sensillum,external sensory organ precursor cell & dorsal mesothoracic disc-537.4,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B,sensory mother cell,supernumerary,sensory neuron,chaeta,secondary neuroblast,apterous-expressing neuron of the lateral cluster of the thorax,orbital bristle,tormogen cell,cardioblast,abdominal 1 dorsal acute muscle 1,A1-7 segment border muscle,embryonic/larval somatic muscle" DRSC27660 K 0.591661259 0.114705723 -0.014509481 0.189382676 -2.187553072 0.165898328 FBgn0013820 Dl::N Dl::N http://flybase.org/reports/FBgn0013820 - engineered_fusion_gene - - - "Dl::N, N" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,cell death defective,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,cell shape defective,somatic clone,lethal" "chordotonal organ precursor cell & ventral thoracic disc-109-68,external sensory organ precursor cell,trichogen cell,photoreceptor cell R8,eye,polar follicle cell,supernumerary,ventral thoracic disc,joint,leg,unguis,wing disc,dorsal compartment,ventral compartment,neuron,EW1 neuron,EW2 neuron,EW3 neuron,GW neuron,ectopic,EW3 neuron | larval stage,embryonic/larval somatic muscle,epidermis,muscle founder cell,presumptive embryonic/larval nervous system,presumptive embryonic/larval central nervous system,embryonic segment,prothoracic metatarsus,prothoracic tarsal segment 3,sex comb,somatic clone,border follicle cell,ventral,eye disc,dorsal,embryonic hindgut,embryonic large intestine,embryonic/larval trachea,embryonic/larval trachea & tracheal tip cellbtl.PS,embryonic/larval dorsal trunk,basal stalk,microtubule109(3)9,abdominal dorsal bipolar neuron dbp,embryonic/larval glial cell,dorsal multidendritic neuron,photoreceptor cell R1,photoreceptor cell R6,oocyte,embryonic/larval optic lobe,temperature conditional,medulla anlage,larval outer optic anlage,male genitalia,secondary neuroblast,supernumerary | third instar larval stage,type II neuroblast" FBgn0035049 Mmp1 Matrix metalloproteinase 1 http://flybase.org/reports/FBgn0035049 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001818, InterPro:IPR016293, InterPro:IPR021190 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001818, InterPro:IPR006026, InterPro:IPR016293, InterPro:IPR021190 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR016293" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001818, InterPro:IPR006026, InterPro:IPR016293, InterPro:IPR021190 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern cell-cell junction organization ; GO:0045216 | inferred from mutant phenotype basement membrane organization ; GO:0071711 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype fasciculation of motor neuron axon ; GO:0097156 | inferred from mutant phenotype adult fat body development ; GO:0007505 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from genetic interaction with NijA imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype basement membrane disassembly ; GO:0034769 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype tissue regeneration ; GO:0042246 | inferred from expression pattern inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern open tracheal system development ; GO:0007424 | inferred from mutant phenotype dorsal trunk growth, open tracheal system ; GO:0035001 | inferred from mutant phenotype" "extracellular matrix ; GO:0031012 | inferred from electronic annotation with InterPro:IPR001818, InterPro:IPR021190 dendrite ; GO:0030425 | inferred from mutant phenotype" "MMP1, mmp1, Mmp1, CG4859, dm1-MMP, l(2)k04809, Dm1-MMP, dmmp1, dMMP1, MMP-1, Mmp 1, MMp1" "IPR018486:Hemopexin, conserved site, IPR018487:Hemopexin-like repeats, IPR000585:Hemopexin-like domain, IPR001818:Peptidase M10, metallopeptidase, IPR002477:Peptidoglycan binding-like, IPR006026:Peptidase, metallopeptidase, IPR016293:Peptidase M10A, stromelysin-type, IPR024079:Metallopeptidase, catalytic domain, IPR021190:Peptidase M10A, IPR033739:Peptidase M10A, catalytic domain" CG4859 11-Aug-17 DroID_v2017_08 "Drer\prg4b, Drer\mmp25a, Drer\vtnb, Drer\mmp13b, Drer\mmp14b, Drer\mmp11b, Drer\mmp9, Drer\mmp15b, Drer\mmp19, Drer\mmp25b, Drer\mmp14a, Drer\mmp16b, Drer\hpx, Drer\mmp21, Drer\mmp30, Drer\mmp20b, Drer\mmp23ba, Drer\mmp13a, Drer\mmp17a, Drer\vtna, Drer\mmp15a, Drer\mmp28, Drer\mmp20a, Drer\mmp24, Drer\mmp2, Drer\mmp11a, Drer\prg4a, Drer\mmp23bb, Drer\mmp16a, Drer\zgc:152945, Drer\mmp17b" - "Cele\zmp-5, Cele\zmp-3, Cele\W01F3.2, Cele\zmp-1, Cele\K03B8.6, Cele\zmp-6, Cele\zmp-2" "Xtro\mmp16, Xtro\mmp24, Xtro\LOC100490019, Xtro\mmp25, Xtro\mmp3, Xtro\mmp17, Xtro\mmp21, Xtro\mmp9, Xtro\mmp1, Xtro\vtn, Xtro\hpx, Xtro\mmp8, Xtro\mmp19, Xtro\mmp14, Xtro\prg4, Xtro\mmp13, Xtro\mmp11, Xtro\mmp15, Xtro\mmp28, Xtro\mmp2, Xtro\alg8" "Mmus\Mmp8, Mmus\Mmp1a, Mmus\Mmp10, Mmus\Mmp16, Mmus\Mmp24, Mmus\Mmp23, Mmus\Mmp19, Mmus\Bsph2, Mmus\Mmp11, Mmus\Mmp13, Mmus\Prg4, Mmus\Mmp28, Mmus\Mmp2, Mmus\Mmp1b, Mmus\Mmp25, Mmus\Vtn, Mmus\Hpx, Mmus\Mmp7, Mmus\Mmp12, Mmus\Mmp15, Mmus\Mmp14, Mmus\Mmp3, Mmus\Mmp9, Mmus\Mmp20, Mmus\Mmp27, Mmus\Mmp17, Mmus\Alg8, Mmus\Bsph1, Mmus\Mmp21" "Hsap\MMP3, Hsap\MMP11, Hsap\MMP15, Hsap\MMP20, Hsap\VTN, Hsap\BSPH1, Hsap\MMP13, Hsap\MMP12, Hsap\MMP14, Hsap\MMP25, Hsap\ELSPBP1, Hsap\MMP9, Hsap\MMP28, Hsap\MMP7, Hsap\MMP21, Hsap\MMP10, Hsap\MMP16, Hsap\MMP17, Hsap\PRG4, Hsap\MMP1, Hsap\MMP26, Hsap\MMP23B, Hsap\MMP27, Hsap\HPX, Hsap\ALG8, Hsap\MMP24, Hsap\MMP2, Hsap\MMP19, Hsap\MMP8" pupal stage salivary gland

"viable,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,hypoactive,developmental rate defective,some die during third instar larval stage,small body,size defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval fat body,embryonic/larval dorsal trunk,embryonic/larval posterior spiracle,embryonic/larval dorsal branch,wing,head,third instar larva,trachea,embryonic/larval trachea,embryonic/larval transverse connective,taenidium,ectopic,mesothoracic tergum,dendritic arborizing neuron,second instar larval cuticle,macrochaeta & adult thoraxdpp.PH,adult thoracic sensillum,chaeta,head | pupal stage,wing | pupal stage,embryonic/larval dorsal branch | third instar larval stage,leg,basement membrane | pupal stage" FBgn0002732 E(spl)malpha-BFM "Enhancer of split malpha, Bearded family member" http://flybase.org/reports/FBgn0002732 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with neur ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with neur Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG8337, HLHmalpha, E(spl)malpha, E(spl)ma, malpha, DmelCG8337, E(spl)mmalpha, E(spl)malpha-BFM, E(spl) malpha" IPR029686:Enhancer of split M4 family CG8337 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 8-17 , larval stage | third instar , embryonic stage | stage >7 , prepupal stage | stage P4 , prepupal stage | stage P4--pupal stage | stage P6 , embryonic stage | stage 6,7 , pupal stage | stage P6 " " ventral neurogenic region

, wing vein

, mesoderm

, sensillum campaniformium &&of wing

, morphogenetic furrow

, wing | restricted

, mesectoderm

, wing blade

, morphogenetic furrow | posterior to

, proneural cluster &&of dorsal mesothoracic disc

, proneural cluster &&of ventral thoracic disc

, wing cell

, wing margin

, dorsal mesothoracic disc | restricted

, proneural cluster

, eye disc

, ventral thoracic disc

" "visible,lethal,partially lethal - majority die,body color defective" "sensillum campaniformium,central nervous system,peripheral nervous system,adult sense organ,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B,macrochaeta,ectopic,sensory mother cell,microchaeta,scutellar bristle,dorsocentral bristle,macrochaeta & scutumpnr-MD237,microchaeta & scutumpnr-MD237,trichogen cell,tormogen cell,thecogen cell,eo neuron,dorsal row & sensory mother cellap-md544,mesothoracic tergum" DRSC16994 E -0.285062749 -0.730975619 0.389453266 -2.278889564 1.049517815 0.346547471 FBgn0003118 pnt pointed http://flybase.org/reports/FBgn0003118 "FBgn0004060, FBgn0005657, FBgn0010925, FBgn0011309" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418, InterPro:IPR003118 repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with edl protein binding ; GO:0005515 | inferred from physical interaction with edl transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap muscle fiber development ; GO:0048747 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype Ras protein signal transduction ; GO:0007265 | traceable author statement heart development ; GO:0007507 | non-traceable author statement R7 cell development ; GO:0045467 | traceable author statement tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype secondary branching, open tracheal system ; GO:0007429 | traceable author statement primary branching, open tracheal system ; GO:0007428 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | non-traceable author statement trachea development ; GO:0060438 | inferred from mutant phenotype secondary branching, open tracheal system ; GO:0007429 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype negative regulation of cardioblast cell fate specification ; GO:0009997 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor determination of adult lifespan ; GO:0008340 | inferred from genetic interaction with aop inferred from genetic interaction with foxo determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype negative regulation of apoptotic signaling pathway ; GO:2001234 | inferred from genetic interaction with hid R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement heart development ; GO:0007507 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement epithelial cell proliferation involved in Malpighian tubule morphogenesis ; GO:0061331 | inferred from mutant phenotype pericardial nephrocyte differentiation ; GO:0061320 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from genetic interaction with tor" nucleus ; GO:0005634 | inferred from direct assay "pnt, pnt-P2, PNT-P1, pointed-RC, PNTP2, CG17077, PNTP1, EK3-2, D-ets-2, ptd, EY3-1, E(E2F)3D, POINT, DMPOINT1A, 3520, 0998/12, 0608/07, 0123/09, ETS2, D-Ets-2, l(3)j1B7, l(3)07825, ets94F, Ets94F, Ets58AB, Ets2, Pnt, l(3)s118306, pointed, PntP2, Pointed-P1, PntP1, pnt-P1, pntP2, EC3-2, Pnt-P1, png, pntegfr, Ets, Pnt2" "IPR000418:Ets domain, IPR003118:Pointed domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR013761:Sterile alpha motif/pointed domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG17077 11-Aug-17 DroID_v2017_08 "Drer\etv5b, Drer\elk3, Drer\elk1, Drer\etv1, Drer\gabpa, Drer\etv4, Drer\ets1, Drer\fli1b, Drer\erfl3, Drer\ets2, Drer\erf, Drer\etv5a, Drer\fli1a, Drer\fev, Drer\elk4, Drer\LOC100537796, Drer\etv2, Drer\erg" - "Cele\elf-1, Cele\tag-97" "Xtro\elk3, Xtro\etv2, Xtro\etv1, Xtro\erg, Xtro\gabpa, Xtro\erf, Xtro\ets1, Xtro\elk4, Xtro\elk1, Xtro\etv3, Xtro\ets2" "Mmus\Elk3, Mmus\Etv1, Mmus\Ets2, Mmus\Etv4, Mmus\Etv3, Mmus\Elk1, Mmus\Fev, Mmus\Elk4, Mmus\Etv2, Mmus\Erf, Mmus\Gabpa, Mmus\Ets1, Mmus\Etv5, Mmus\Fli1, Mmus\Erg" "Hsap\ERG, Hsap\ETV4, Hsap\GABPA, Hsap\ETV2, Hsap\ETS1, Hsap\ERF, Hsap\ELK4, Hsap\ETV3, Hsap\ELK1, Hsap\ELK3, Hsap\FEV, Hsap\FLI1, Hsap\ETV1, Hsap\ETV5, Hsap\ETV3L, Hsap\ETS2" " embryonic stage | stage 12-13 , embryonic stage | stage >=11 , embryonic stage | stage 12-14 , larval stage | third instar , embryonic stage | stage 6-12 , larval stage , embryonic stage , embryonic stage | early " " mesoderm

, embryonic/larval tracheal system

, interface glial cell

, ommatidium | restricted

, morphogenetic furrow | posterior to

, lateral ventral neurectoderm

, VUM neuron

, morphogenetic furrow

, maxillary segment

, imaginal disc primordium

, mandibular segment

, midline glial cell

, labial segment

, organism | 100% egg length

" larval stage " morphogenetic furrow | subset

, ommatidium | precursor

" "viable,fertile,cell polarity defective,planar polarity defective,visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,dominant,neuroanatomy defective,somatic clone,mitotic cell cycle defective,homeotic,female sterile,female semi-sterile,size defective" "embryo,cardioblast,ectopic,ommatidium,photoreceptor,photoreceptor cell R7,eye photoreceptor cell,eye,interface glial cell,presumptive embryonic/larval central nervous system,midline glial cell,dorsal neurohemal organ,germarium,spectrosome | supernumeraryunspecified,embryonic/larval dorsal branch & terminal tracheal cell | somatic clone,terminal tracheal cell,embryonic/larval tracheal system,stomatogastric nervous system,macrochaeta,embryonic pericardial cell,lch5 neuron,midgut,abdominal 1 anterior commissure,abdominal 2 anterior commissure,abdominal 3 anterior commissure,abdominal 4 anterior commissure,abdominal 5 anterior commissure,abdominal 6 anterior commissure,abdominal 7 anterior commissure,abdominal 8 anterior commissure,abdominal 1 posterior commissure,abdominal 2 posterior commissure,abdominal 3 posterior commissure,abdominal 4 posterior commissure,abdominal 5 posterior commissure,abdominal 6 posterior commissure,abdominal 7 posterior commissure,abdominal 8 posterior commissure,wing,embryonic/first instar larval cuticle,ventral,adult salivary gland primordium,gastric caecum,midgut constriction 1,midgut chamber 3,visceral mesoderm,embryonic Malpighian tubule,embryonic ventral epidermis,dorsal appendage,maternal effect,somatic clone,dorsal air sac primordium,type II neuroblast,embryonic/larval glial cell,anterior fascicle sensory neuron,posterior fascicle sensory neuron,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,embryonic/larval ganglionic branch,lateral trunk anterior branch,lateral trunk posterior branch,embryonic/larval trachea,tracheal metamere,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,dorsal branch primordium,commissure,ventral nerve cord,eye disc,mitotic cell cycle | somatic clone,Bolwig nerve,presumptive embryonic/larval tracheal system,Malpighian tubule,genital disc primordium,mesoderm,embryonic/larval pericardial cell,A1-7 dorsal acute muscle 1,A1-7 ventral acute muscle 2,precursor,denticle belt,exit glial cell,glial cell,trachea,tracheal fusion cell,supernumerary,ommatidial precursor cluster,embryonic/larval dorsal trunk,bract,abdominal neuromere,abdominal 1 ventral monoscolopidial chordotonal organ vch1,abdominal 2 ventral monoscolopidial chordotonal organ vch1,abdominal 3 ventral monoscolopidial chordotonal organ vch1,abdominal 4 ventral monoscolopidial chordotonal organ vch1,abdominal 5 ventral monoscolopidial chordotonal organ vch1,abdominal 6 ventral monoscolopidial chordotonal organ vch1,abdominal 7 ventral monoscolopidial chordotonal organ vch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron,cephalopharyngeal skeleton,anterior commissure,ganglionic branch primordium,photoreceptor cell R1,photoreceptor cell R6,wing disc,central nervous system,melanotic mass,hemocyte,antenna,morphogenetic furrow,submarginal cell,wing vein L4,pigment cell,photoreceptor cell R8,rhabdomere R8,muscle founder cell,dorsal oblique muscle,pericardial cell,dorsal acute muscle,cone cell,embryonic/larval brain,ventral nerve cord | larval stage,secondary neuroblast,ectopic | larval stage" DRSC23204 K 1.09824732 2.796468736 FBgn0001645 l(1)dn25 lethal (1) discs normal 25 http://flybase.org/reports/FBgn0001645 - gene - - - "l(1)d norm-25, l(1)d.norm.-25, l(1)dn25" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0014058 Su(tor)2-48 Su(tor)2-48 http://flybase.org/reports/FBgn0014058 - gene - - - Su(tor)2-48 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0021875 Zfrp8 Zinc finger protein RP-8 http://flybase.org/reports/FBgn0021875 FBgn0034981 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 ribosomal small subunit binding ; GO:0043024 | inferred from direct assay DNA binding ; GO:0003677 | inferred from sequence or structural similarity ribosomal small subunit biogenesis ; GO:0042274 | inferred from mutant phenotype embryonic hemopoiesis ; GO:0035162 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of cytoplasmic translation ; GO:2000765 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype somatic stem cell division ; GO:0048103 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AF077950 "CG3260, zfrp8, 137/5, l(2)k13705, Zfrp8, PDCD2" "IPR002893:Zinc finger, MYND-type, IPR007320:Programmed cell death protein 2, C-terminal" CG3260 11-Aug-17 DroID_v2017_08 "Drer\pdcd2l, Drer\pdcd2" Scer\TSR4 Cele\pdcd-2 "Xtro\pdcd2, Xtro\pdcd2l" "Mmus\Pdcd2l, Mmus\Pdcd2" "Hsap\SMYD1, Hsap\PDCD2, Hsap\PDCD2L" "lethal,recessive,developmental rate defective,hyperplasia,lethal - all die before end of larval stage,some die during larval stage,melanotic necrosis,viable" "female germline stem cell,ovariole,spectrosomenos.UTR.THsimVP16,follicle stem cell,somatic clone,female germline cyst,germline clone,spectrosome | germline clone,embryonic/larval lymph gland,embryonic/larval hemocyte,supernumerary,lamellocyte,plasmatocyte,crystal cell,melanotic mass" DRSC04352 K 0.781602195 0.115796747 -0.053186287 0.613806657 2.21922239 1.274304349 FBgn0010452 trn tartan http://flybase.org/reports/FBgn0010452 FBgn0025231 protein_coding_gene - "imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cell adhesion ; GO:0007155 | non-traceable author statement motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype cell migration ; GO:0016477 | traceable author statement larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype" - "trn, CT31487, 0641/17, 0024/05, anon-EST:fe2B1, CG11280" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG11280 11-Aug-17 DroID_v2017_08 "Drer\lrrn3, Drer\zgc:172282, Drer\lrrc15, Drer\lrrn1, Drer\lrfn4b, Drer\zgc:153913, Drer\lrfn5a, Drer\aspn, Drer\flrt3, Drer\si:ch211-180f4.1, Drer\LOC100535105, Drer\lrfn1, Drer\lrfn2b, Drer\lrrn2, Drer\flrt1a, Drer\lrfn4a, Drer\flrt1b, Drer\lrfn5b, Drer\LOC563710, Drer\zmp:0000001073" Scer\CYR1 "Cele\lron-11, Cele\let-4" "Xtro\lrfn1, Xtro\lrfn2, Xtro\lrrn1-like, Xtro\flrt1, Xtro\lrfn5, Xtro\lrrn3, Xtro\lrfn3, Xtro\flrt3, Xtro\tril, Xtro\LOC100488097, Xtro\lrrn1" "Mmus\Lrrn3, Mmus\Lrrn1, Mmus\Lrrn2, Mmus\Lrrtm2, Mmus\Flrt1, Mmus\Bgn, Mmus\Lrrtm1, Mmus\Lingo3, Mmus\Lrfn3, Mmus\Lrrtm4, Mmus\Lrfn5, Mmus\Tril, Mmus\Cpn2, Mmus\Lrrtm3, Mmus\Lrit2, Mmus\Rxfp2, Mmus\Lrfn1, Mmus\Lrfn4, Mmus\Lrfn2, Mmus\Flrt3" "Hsap\BGN, Hsap\LRRC70, Hsap\LRRN3, Hsap\CPN2, Hsap\LRFN1, Hsap\LRFN2, Hsap\LRFN4, Hsap\LRRTM1, Hsap\FLRT1, Hsap\LRFN3, Hsap\LRFN5, Hsap\LRRTM3, Hsap\LINGO3, Hsap\LRRN1, Hsap\LGR5, Hsap\LRIT2, Hsap\LRRN2, Hsap\LRRTM4, Hsap\FLRT3" " embryonic stage | stage >=8 , embryonic stage | stage 15-16 , larval stage | third instar , embryonic stage | stage 15,16 , embryonic stage | stage 16,17 , larval stage&&pupal stage , embryonic stage | stage 5 , embryonic stage -- adult stage " " sense organ | precursor

, embryonic/larval hindgut

, ventral thoracic disc

, stomodeum

, morphogenetic furrow | anterior

, proctodeum

, central nervous system

, larval outer optic anlage

,

pair rule , embryonic peripheral nervous system | restricted

, eye-antennal disc

, larval inner optic anlage

, dorsal mesothoracic disc

, peripheral nervous system

, morphogenetic furrow | posterior to

" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,some die during immature adult stage,somatic clone,viable" "lch5 neuron,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,A1-7 lateral transverse muscle 4,A1-7 dorsal transverse muscle 1,embryonic/larval salivary gland,presumptive embryonic/larval peripheral nervous system,embryonic/larval somatic muscle,antennal lobe projection neuron lPN,somatic clone,dendrite | somatic clone,lateral trunk primordium,pretarsus,dorsal trunk primordium,intersegmental nerve,motor neuron,wing disc,ventral compartment,ventral thoracic disc,motor neuron | larval stage" FBgn0000440 dft deformed tergites http://flybase.org/reports/FBgn0000440 - gene - - - dft - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male fertile,poor,partially lethal - majority live,viable,male,male sterile" "eye,wing,macrochaeta,posterior scutellar bristle,dorsocentral bristle,adult abdomen,adult abdomen & microchaeta" FBgn0025761 l(3)93DFa lethal (3) 93DFa http://flybase.org/reports/FBgn0025761 - gene - - - l(3)93DFa - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035026 Fcp1 TFIIF-interacting CTD phosphatase http://flybase.org/reports/FBgn0035026 protein_coding_gene CTD phosphatase activity ; GO:0008420 | inferred from sequence or structural similarity with HGNC:2498 CTD phosphatase activity ; GO:0008420 | inferred from biological aspect of ancestor with PANTHER:PTN000555199 dephosphorylation of RNA polymerase II C-terminal domain ; GO:0070940 | inferred from biological aspect of ancestor with PANTHER:PTN000555199 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:2498 neurogenesis ; GO:0022008 | inferred from mutant phenotype "polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay DNA-directed RNA polymerase II, holoenzyme ; GO:0016591 | inferred from biological aspect of ancestor with PANTHER:PTN000555199" "DmFcp1, CG12252, Fcp1, fcp1, Dmfcp1, 21483550" "IPR001357:BRCT domain, IPR004274:FCP1 homology domain, IPR011947:FCP1-like phosphatase, phosphatase domain, IPR023214:HAD-like domain" CG12252 11-Aug-17 DroID_v2017_08 Drer\ctdp1 Scer\FCP1 "Cele\fcp-1, Cele\W04A8.1" Xtro\ctdp1 Mmus\Ctdp1 Hsap\CTDP1 "lethal - all die during third instar larval stage,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,visible,increased cell death,wild-type,lethal - all die before end of prepupal stage,some die during third instar larval stage,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval neuroblast,ganglion mother cell,wing,eye,imaginal disc,polytene chromosome puff,polytene chromosome puffhs.PB,egg,maternal effect" FBgn0023130 a6 a6 http://flybase.org/reports/FBgn0023130 - protein_coding_gene - embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from expression pattern - "CG3771, EG:9D2.3, a6" - CG3771 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" FBgn0003240 rey rough eye on X http://flybase.org/reports/FBgn0003240 - gene - - - "re, rey" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,visible,recessive,female fertile,poor,viable,female" "eye,adult thorax" FBgn0000926 fs(1)se female sterile (1) small eggs http://flybase.org/reports/FBgn0000926 - gene - - - "fs(1)107, fs(1)se" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" egg chamber FBgn0038454 CG10324 - http://flybase.org/reports/FBgn0038454 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:30677 CG10324 "IPR014722:Ribosomal protein L2 domain 2, IPR026822:Spp2/MOS2, G-patch domain" CG10324 11-Aug-17 DroID_v2017_08 Drer\gpkow Scer\SPP2 "Cele\gkow-1, Cele\F53B2.1" Xtro\gpkow Mmus\Gpkow Hsap\GPKOW "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0013764 Chi Chip http://flybase.org/reports/FBgn0013764 "FBgn0020536, FBgn0024338" protein_coding_gene "transcription factor activity, transcription factor binding ; GO:0000989 | inferred from electronic annotation with InterPro:IPR030174 LIM domain binding ; GO:0030274 | inferred from electronic annotation with InterPro:IPR030174 transcription factor binding ; GO:0008134 | inferred from physical interaction with pnr protein binding ; GO:0005515 | inferred from physical interaction with Bx protein binding ; GO:0005515 | inferred from physical interaction with Iswi inferred from physical interaction with tou RNA polymerase II transcription factor binding ; GO:0001085 | inferred from physical interaction with tup" "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR030174 phagocytosis ; GO:0006909 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | traceable author statement regulation of eclosion ; GO:0007563 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Chip, chip, dLdb, dLDB/Chip, Ldb, l(2)04405, l(2)k04405, CG3924, Chi, CHIP, LDB, chi" "IPR030174:LIM domain-binding protein 2, IPR029005:LIM-domain binding protein/SEUSS" CG3924 11-Aug-17 DroID_v2017_08 "Drer\ldb2b, Drer\ldb1a, Drer\ldb2a" - Cele\ldb-1 "Xtro\ldb1, Xtro\ldb2" "Mmus\Ldb1, Mmus\Ldb2" "Hsap\LDB2, Hsap\LDB1" embryonic stage -- adult stage " larval stage , embryonic stage && larval stage " " embryonic/larval fat body

,

, embryonic/larval salivary gland

, imaginal disc

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,visible,somatic clone,size defective,wild-type,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,non-rescuable maternal effect,neuroanatomy defective,eclosion defective,heat sensitive,partially lethal - majority die,some die during pupal stage" "eye,ectopic,somatic clone,head capsule,vibrissae,rostral membrane,ocellus,antenna,maxillary palpus,eye-antennal disc,somatic clone - Minute background,photoreceptor cell,somatic clone | third instar larval stage,thorax,wing,embryo,dorsocentral bristle,posterior postalar bristle,scutellar bristle,supernumerary,adult thorax,wing margin,dorsal compartment,wing disc,leg,tarsal segment 4,unguis,interneuron,embryonic/larval neuron,germline clone,embryonic/first instar larval cuticle,adult antennal lobe projection neuron,antennal lobe projection neuron adPN,antennal lobe glomerulus VA1,antennal lobe glomerulus D,antennal lobe glomerulus DL1,antennal lobe glomerulus VM7,antennal lobe glomerulus VA3,antennal lobe glomerulus VM2,antennal lobe glomerulus DM6,antennal lobe glomerulus DA1,antennal lobe glomerulus VA5,antennal lobe glomerulus DM5,antennal lobe glomerulus DM2,antennal lobe glomerulus DM1,subesophageal ganglion,pretarsus,antennal lobe glomerulus VA1v,dorsal/ventral compartment boundary,distal,heat sensitive,alula,mesothoracic tergum,anterior dorsocentral bristle,posterior dorsocentral bristle,chaeta,trichogen cell" DRSC04602 K -0.519128937 -0.283141601 0.672925901 0.111594062 1.616826259 0.749218418 FBgn0024798 Dipr Distal into proximal http://flybase.org/reports/FBgn0024798 - gene - - - Dipr - - 11-Aug-17 DroID_v2017_08 - - - - - - "wild-type,viable,visible,dominant,homeotic,body color defective" "wing,distal,dorsal triple row,medial triple row,ventral triple row,trichome of the posterior wing margin,wing hair,wing vein,proximal,capitellum,tarsal segment 2,tarsal segment 3,tarsal segment 4,prothoracic tarsal segment 2,sex comb,ectopic,basal cylinder,pseudotrachea,metatarsus" FBgn0027233 l(1)G0286 lethal (1) G0286 http://flybase.org/reports/FBgn0027233 - gene - - - l(1)G0286 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0010602 lwr lesswright http://flybase.org/reports/FBgn0010602 "FBgn0010523, FBgn0015755, FBgn0022761" protein_coding_gene SUMO ligase activity ; GO:0061665 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with dl SUMO transferase activity ; GO:0019789 | inferred from sequence or structural similarity with SGD:S000002222 heat shock protein binding ; GO:0031072 | inferred from physical interaction with Hsp23 inferred from physical interaction with Hsp27 ubiquitin activating enzyme binding ; GO:0033134 | inferred from physical interaction with Aos1 germ cell migration ; GO:0008354 | inferred from mutant phenotype protein sumoylation ; GO:0016925 | inferred from sequence or structural similarity with SGD:S000002222 humoral immune response ; GO:0006959 | inferred from mutant phenotype protein sumoylation ; GO:0016925 | inferred from mutant phenotype hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype protein import into nucleus ; GO:0006606 | inferred from mutant phenotype inferred from physical interaction with dl cellular response to transforming growth factor beta stimulus ; GO:0071560 | inferred from genetic interaction with dpp dorsal closure ; GO:0007391 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from genetic interaction with Axs inferred from genetic interaction with mei-218 inferred from genetic interaction with ncd female meiosis chromosome segregation ; GO:0016321 | inferred from genetic interaction with nod negative regulation of hemocyte proliferation ; GO:0035207 | inferred from mutant phenotype spectrosome organization ; GO:0030721 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs zygotic specification of dorsal/ventral axis ; GO:0007352 | inferred from genetic interaction with cact inferred from genetic interaction with dl negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype cellular protein modification process ; GO:0006464 | inferred from genetic interaction with dl inferred from genetic interaction with smt3 inferred from physical interaction with dl inferred from physical interaction with smt3 "nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay condensed chromosome outer kinetochore ; GO:0000940 | inferred from direct assay" "lwr, ubc9, dUbc9, Ubc9, FBgn0010602, i56, i105, CG3018, dUBC9, DmUbc9, l(2)01519, semi, DUbc9, Dmubc9, dip4, UBC9, hbl, Lwr, Ubc-9, l(2)05487, l(2)05486, l(2)02858, Ubc 9, Iwr, UbcD9" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR027230:SUMO-conjugating enzyme Ubc9, IPR023313:Ubiquitin-conjugating enzyme, active site" CG3018 11-Aug-17 DroID_v2017_08 "Drer\ube2ia, Drer\ube2ib" Scer\UBC9 "Cele\ubc-9, Cele\F29B9.5, Cele\uev-2" Xtro\ube2i Mmus\Ube2i Hsap\UBE2I " embryonic stage , embryonic stage | syncytial blastoderm "

anterior " embryonic stage , adult stage | female " organism

"immune response defective,tumorigenic,lethal,recessive,rescuable maternal effect,maternal effect,neuroanatomy defective,somatic clone,melanotic mass phenotype,developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,partially,enhancer of variegation,partially lethal - majority die,visible,wild-type,mitotic cell cycle defective,germline clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval fat body,embryonic/larval hemocoel,embryonic epidermis,embryonic head,embryonic thoracic segment,embryonic abdominal segment,leg,adult head,wing,eye,neuroblast,somatic clone,embryonic/larval hemocyte,supernumerary,lamellocyte,plasmatocyte,hemocyte,crystal cell,melanotic mass,hemocyte & nucleus | supernumerary,embryonic/first instar larval cuticle,adult antennal lobe projection neuron DL1 adPN,antennal lobe glomerulus DL1,dendrite | somatic clone,eye disc" DRSC00828 E 0.9479729 -0.705051992 1.685084091 -0.070291204 -0.529128007 0.962574336 FBgn0005614 trpl transient receptor potential-like http://flybase.org/reports/FBgn0005614 FBgn0042195 protein_coding_gene calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity with HGNC:12333 inferred from sequence or structural similarity with MGI:MGI:109528 cation channel activity ; GO:0005261 | traceable author statement ion transmembrane transporter activity ; GO:0015075 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VJJ7 light-activated ion channel activity ; GO:0010461 | inferred from direct assay calcium channel activity ; GO:0005262 | inferred from direct assay store-operated calcium channel activity ; GO:0015279 | non-traceable author statement calmodulin binding ; GO:0005516 | inferred from direct assay calcium channel activity ; GO:0005262 | inferred from genetic interaction with trp calmodulin binding ; GO:0005516 | inferred from sequence or structural similarity with trp protein binding ; GO:0005515 | inferred from physical interaction with inaD inferred from physical interaction with FKBP59 calmodulin binding ; GO:0005516 | traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:P19334 cation channel activity ; GO:0005261 | inferred from direct assay calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity identical protein binding ; GO:0042802 | inferred from physical interaction with trpl store-operated calcium channel activity ; GO:0015279 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 "phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype detection of light stimulus involved in visual perception ; GO:0050908 | inferred from sequence or structural similarity with UniProtKB:P19334 response to light stimulus ; GO:0009416 | traceable author statement body fluid secretion ; GO:0007589 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity with UniProtKB:P19334 ion transport ; GO:0006811 | non-traceable author statement calcium ion transport ; GO:0006816 | inferred from direct assay cation transport ; GO:0006812 | inferred from direct assay sensory perception of sound ; GO:0007605 | inferred from mutant phenotype calcium-mediated signaling ; GO:0019722 | traceable author statement calcium-mediated signaling ; GO:0019722 | inferred from mutant phenotype calcium ion transmembrane transport ; GO:0070588 | inferred from genetic interaction with trp cellular response to anoxia ; GO:0071454 | inferred from genetic interaction with trp manganese ion transport ; GO:0006828 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 regulation of cytosolic calcium ion concentration ; GO:0051480 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity with HGNC:12333 inferred from sequence or structural similarity with MGI:MGI:109528 calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity" rhabdomere ; GO:0016028 | traceable author statement dendrite ; GO:0030425 | inferred from direct assay rhabdomere microvillus membrane ; GO:0035997 | inferred from direct assay cation channel complex ; GO:0034703 | inferred from physical interaction with trp plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with trp plasma membrane ; GO:0005886 | traceable author statement inaD signaling complex ; GO:0016027 | inferred from physical interaction with inaD integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 intracellular ; GO:0005622 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay cation channel complex ; GO:0034703 | inferred from physical interaction with Trpγ integral component of membrane ; GO:0016021 | non-traceable author statement "trpl, TRPL, dTRPL, DmTRPL, dTrpL, TrpL, trp-l, CG1694, CG18345, Trpl, TRP-Like, trpL" "IPR002110:Ankyrin repeat, IPR002153:Transient receptor potential channel, canonical, IPR004729:Transient receptor potential channel, IPR005821:Ion transport domain, IPR013555:Transient receptor ion channel domain, IPR020683:Ankyrin repeat-containing domain" CG18345 11-Aug-17 DroID_v2017_08 "Drer\zgc:110224, Drer\trpc7a, Drer\trpc6a, Drer\trpc4b, Drer\trpc4a, Drer\trpc5a, Drer\trpn1, Drer\trpc1, Drer\trpc2a, Drer\trpc2b, Drer\trpc3" - "Cele\trp-1, Cele\trp-2" "Xtro\LOC100492885, Xtro\trpc6, Xtro\trpc4, Xtro\trpc1, Xtro\trpc2, Xtro\trpc3, Xtro\trpc5" "Mmus\Trpc1, Mmus\Trpc5, Mmus\Trpc7, Mmus\Trpc3, Mmus\Trpc2, Mmus\Trpc6, Mmus\Trpc4" "Hsap\TRPC7, Hsap\TRPC1, Hsap\TRPC5, Hsap\TRPC3, Hsap\TRPC6, Hsap\TRPC4" adult stage photoreceptor cell

adult stage rhabdomere

"neurophysiology defective,visual behavior defective,chemosensitive behavior defective,taste perception defective,thermotaxis behavior defective,wild-type,auditory perception defective,viable" "photoreceptor cell,photoreceptor,photoreceptor cell & axon,S-type sensilla S6,eye photoreceptor cell,L-type sensilla L2,Malpighian tubule" DRSC06729 K 0.633569824 0.210869085 0.16445543 1.097994 1.539794396 -0.998261165 FBgn0025286 RpL31 Ribosomal protein L31 http://flybase.org/reports/FBgn0025286 "FBgn0033430, FBgn0062997" protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000054, InterPro:IPR020052 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement" ribosome ; GO:0005840 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "anon-EST:Posey68, CG1821, BcDNA:RE59131, RpL31, M(2)45F, Rp L31" "IPR000054:Ribosomal protein L31e, IPR020052:Ribosomal protein L31e, conserved site, IPR023621:Ribosomal protein L31e domain" CG1821 11-Aug-17 DroID_v2017_08 Drer\rpl31 "Scer\RPL31A, Scer\RPL31B" Cele\rpl-31 Xtro\rpl31 Mmus\Rpl31 Hsap\RPL31 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC06716 IEK -1.722202266 -1.725588729 -1.417356415 -3.706249868 -0.831050641 2.684574962 FBgn0002791 mr morula http://flybase.org/reports/FBgn0002791 FBgn0034947 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000231993 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000231993 ubiquitin protein ligase activity ; GO:0061630 | inferred from sequence or structural similarity with SGD:S000004117 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000231993 regulation of cell cycle ; GO:0051726 | traceable author statement negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from sequence or structural similarity with SGD:S000004117 modulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype ubiquitin ligase complex ; GO:0000151 | inferred from direct assay anaphase-promoting complex ; GO:0005680 | inferred from direct assay anaphase-promoting complex ; GO:0005680 | traceable author statement "APC2/mr, CG3060, mr, APC2, dAPC2, Apc2, MR, Mr" "IPR001373:Cullin, N-terminal, IPR014786:Anaphase-promoting complex subunit 2, C-terminal, IPR016158:Cullin homology, IPR011991:Winged helix-turn-helix DNA-binding domain" CG3060 11-Aug-17 DroID_v2017_08 Drer\anapc2 "Scer\APC2, Scer\LTV1" Cele\apc-2 Xtro\anapc2 Mmus\Anapc2 Hsap\ANAPC2 "viable,fertile,lethal,partially,neurophysiology defective,neuroanatomy defective,recessive,mitotic cell cycle defective,somatic clone,germline clone,visible,sterile,female sterile" "embryonic/larval neuromuscular junction,NMJ bouton,supernumerary,nurse cell & nuclear chromosome,nurse cell & spindle,eye,somatic clone,macrochaeta,mitotic cell cycle | larval stage | somatic clone,mitotic cell cycle | germline clone,spindle | germline clone,hindgut imaginal ring,embryonic/larval salivary gland,ring gland,nurse cell,spindle | maternal effect,nuclear chromosome | maternal effect,nurse cell & nucleus,follicle cell,nurse cell ring canal,egg,embryo,mitotic cell cycle | embryonic stage,polar body nucleus,spindle | embryonic stage,tergite,trichogen cell,mesothoracic tergum" DRSC04332 K -0.379924778 -0.188079924 1.327161857 -0.056307541 0.277123298 -1.897025145 FBgn0036516 CG7656 - http://flybase.org/reports/FBgn0036516 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12482 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12482 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000629795 neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 CG7656 "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG7656 11-Aug-17 DroID_v2017_08 "Drer\cdc34a, Drer\ube2g2, Drer\ube2g1b, Drer\ube2r2, Drer\cdc34b, Drer\ube2g1a" "Scer\CDC34, Scer\UBC7" "Cele\ubc-14, Cele\ubc-3, Cele\ubc-7" "Xtro\cdc34, Xtro\ube2g2, Xtro\ube2g1, Xtro\ube2r2" "Mmus\Ube2r2, Mmus\Ube2g1, Mmus\Cdc34, Mmus\Ube2g2" "Hsap\UBE2R2, Hsap\CDC34, Hsap\UBE2G2, Hsap\UBE2G1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,chaeta,supernumerary,mesothoracic tergum" DRSC10900 K 0.469023476 0.3818229 0.319878193 0.088338656 1.51916032 0.468978563 FBgn0000357 Cp18 Chorion protein 18 http://flybase.org/reports/FBgn0000357 FBgn0004941 protein_coding_gene structural constituent of chorion ; GO:0005213 | traceable author statement multicellular organism development ; GO:0007275 | inferred from electronic annotation with InterPro:IPR005649 chorion ; GO:0042600 | inferred from electronic annotation with InterPro:IPR005649 "Cp18, s-18, s18, S-18, CP18, ACE3, Dms18, S18, cp18, s18-1, E5, CG6517" IPR005649:Chorion 2 CG6517 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage | stage S11-14 , adult stage && oogenesis stage | stage S13-14 , adult stage | female " follicle cell

" adult stage | female , adult stage && oogenesis stage | stage S13-14 , embryonic stage , oogenesis stage | stage S13-14 " " ovary

{ v fs(1)A1059K1 } , follicle cell

, ovary

{ 0 swa6 } , vitelline membrane

, ovary

, ovary

{ v mus101K451 } " viable FBgn0020307 dve defective proventriculus http://flybase.org/reports/FBgn0020307 "FBgn0010496, FBgn0041142" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with vvl sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000387730 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from expression pattern reproductive structure development ; GO:0048608 | inferred from mutant phenotype copper ion import ; GO:0015677 | inferred from mutant phenotype imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with vvl" nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "Dve, Dve-s, l(2)01738, dep, CG5799, dve, DVE, SATB1" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032392:SATB, ubiquitin-like oligomerisation domain" CG5799 11-Aug-17 DroID_v2017_08 "Drer\satb2, Drer\LOC571757, Drer\satb1a" - Cele\dve-1 Xtro\satb1 "Mmus\Satb1, Mmus\Satb2" "Hsap\SATB1, Hsap\SATB2" " embryonic stage | stage >=9 , embryonic stage | stage 13 , embryonic stage | stage 12 , embryonic stage | stage 16 , embryonic stage | stage 13-17 , embryonic stage | 0-18 hr , embryonic stage | stage 9 " " anterior midgut proper primordium | restricted

, ventral nerve cord | restricted

, posterior midgut proper primordium | anterior

, embryonic/larval pharynx | vicinity of

, proventriculus outer layer

, embryonic/larval midgut | restricted

, embryonic brain | restricted

, mesectoderm | restricted

" " embryonic stage | stage 16 , larval stage | third instar , embryonic stage | stage >=11 , embryonic stage | stage >=13 , embryonic stage | stage 10 " " proventriculus outer layer

, dorsal mesothoracic disc | restricted

, anterior midgut proper primordium | restricted

, posterior embryonic/larval midgut | restricted

, specialised larval midgut cell | precursor

, mid embryonic/larval midgut | restricted

, stomodeum

" "mating behavior defective,female,visible,partially lethal - majority die,partially lethal,small body,recessive,lethal,viable,fertile,somatic clone,lethal - all die before end of larval stage,some die during larval stage" "male accessory gland,male accessory gland main cell,cuprophilic cell,wing,midgut,proventriculus,male accessory gland secondary cell,larva,embryonic/larval midgut,somatic clone,wing margin bristle,ectopic,proximal,wing vein L2,wing vein L5,distal,wing disc,embryonic/larval proventriculus,proventriculus outer layer,proventriculus inner layer,joint,tarsal segment,dorsal | pharate adult stage,eye disc,male limited,heat sensitive" FBgn0004132 boca boca http://flybase.org/reports/FBgn0004132 "FBgn0033193, FBgn0050498" protein_coding_gene - protein targeting to membrane ; GO:0006612 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from expression pattern Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype inferred from genetic interaction with wg proboscis development ; GO:0048728 | inferred from mutant phenotype low-density lipoprotein receptor particle metabolic process ; GO:0032799 | inferred from mutant phenotype endoplasmic reticulum lumen ; GO:0005788 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "CG1364, l(2)43Ea, CG30498, boca, Boca, dmBoca" IPR019330:Mesoderm development candidate 2 CG30498 11-Aug-17 DroID_v2017_08 Drer\mesdc2 - "Cele\bmy-1, Cele\srg-69" Xtro\mesdc2 Mmus\Mesdc2 Hsap\MESDC2 "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage,viable" "wing margin bristle,cell autonomous,somatic clone,cell non-autonomous,ectopic,dorsocentral bristle,eye,adult head,dorsal,wing disc,ventral thoracic disc,distal,yolk,germline clone,proboscis" FBgn0036577 CG13073 - http://flybase.org/reports/FBgn0036577 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG13073 - CG13073 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell FBgn0060611 l(3)S090303 lethal (3) S090303 http://flybase.org/reports/FBgn0060611 gene - - - "0903/03, l(3)S090303" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0062625 Mod(var)1116 Mod(var)1116 http://flybase.org/reports/FBgn0062625 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1116, Mod(var)1116" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,viable" FBgn0019662 qm quemao http://flybase.org/reports/FBgn0019662 - protein_coding_gene - isoprenoid biosynthetic process ; GO:0008299 | inferred from electronic annotation with InterPro:IPR000092 embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype - "CG8593, qm, GGPPS, bro2, GGPPS/qm, Qm" "IPR000092:Polyprenyl synthetase, IPR008949:Isoprenoid synthase domain, IPR033749:Polyprenyl synthetase, conserved site" CG8593 11-Aug-17 DroID_v2017_08 Drer\ggps1 Scer\BTS1 Cele\coq-1 Xtro\ggps1 Mmus\Ggps1 Hsap\GGPS1 embryonic stage -- adult stage "wild-type,viable,fertile,visible,recessive,female fertile,male sterile,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,germline clone,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,partially lethal - majority die" "nurse cell ring canal,germline clone,egg chamber,macrochaeta,adult thorax & macrochaeta,sternopleural bristle,head bristle,sex comb,adult abdomen,adult cuticle & abdomen,macrochaeta & adult abdomen,pole cell,larva,cephalopharyngeal skeleton,embryonic pericardial cell,cardioblast,pole cell & embryonic nervous system,embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0037838 CG4089 - http://flybase.org/reports/FBgn0037838 protein_coding_gene - cellular protein modification process ; GO:0006464 | inferred from electronic annotation with InterPro:IPR004344 - CG4089 IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase CG4089 11-Aug-17 DroID_v2017_08 - Scer\PBY1 "Cele\ttll-4, Cele\ttll-15" Xtro\ttll4 "Mmus\Ttll1, Mmus\Ttll4" "Hsap\TTLL1, Hsap\TTLL4, Hsap\TTLL5" viable FBgn0038869 Smyd5 "SET and MYND domain containing, class 5" http://flybase.org/reports/FBgn0038869 protein_coding_gene S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from sequence or structural similarity with SGD:S000001250 histone lysine methylation ; GO:0034968 | inferred from sequence or structural similarity with SGD:S000001250 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with SGD:S000001250 "Smyd5, CG3353" "IPR016024:Armadillo-type fold, IPR001214:SET domain" CG3353 11-Aug-17 DroID_v2017_08 "Drer\smyd4, Drer\smyd5, Drer\smyd1a, Drer\smyd2a, Drer\alg1, Drer\smyd3, Drer\smyd2b, Drer\smyd1b" "Scer\SET5, Scer\SET6" "Cele\set-30, Cele\algn-1" "Xtro\smyd4, Xtro\alg1, Xtro\smyd1, Xtro\smyd5" "Mmus\Alg1, Mmus\Smyd3, Mmus\Smyd2, Mmus\Smyd5, Mmus\Smyd1, Mmus\Smyd4" "Hsap\ALG1, Hsap\SMYD2, Hsap\ALG1L, Hsap\SMYD3, Hsap\ALG1L2, Hsap\SMYD5, Hsap\SMYD4, Hsap\SMYD1" "neuroanatomy defective,viable" "Kenyon cell,adult mushroom body" DRSC15483 E 0.322704837 0.241112724 2.368212694 1.115961955 -0.985748929 -0.633077595 FBgn0052685 ZAP3 ZAP3 http://flybase.org/reports/FBgn0052685 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG2971, CG12647, CG12646, ZAP3, CG32685" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026314:YLP motif-containing protein 1" CG32685 11-Aug-17 DroID_v2017_08 "Drer\ylpm1, Drer\zmp:0000000906" - "Cele\glh-4, Cele\C35E7.4" Xtro\ylpm1 "Mmus\Ylpm1, Mmus\Dbpht2" Hsap\YLPM1 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC18249 I -0.030640317 1.643603085 0.449084824 0.451095422 -0.436420371 -0.495052033 FBgn0038168 omd oocyte maintenance defects http://flybase.org/reports/FBgn0038168 protein_coding_gene - snRNA 3'-end processing ; GO:0034472 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:29352 "CG9591, Omd, omd, IntS5" "IPR029444:Integrator complex subunit 5, C-terminal, IPR029445:Integrator complex subunit 5, N-terminal" CG9591 11-Aug-17 DroID_v2017_08 Drer\ints5 - Cele\Y51A2D.7 Xtro\ints5 Mmus\Ints5 Hsap\INTS5 "lethal,female fertile,poor,viable,fertile,neuroanatomy defective,partially lethal - majority die,visible" "wing,wing vein,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC16507 IK -0.914094748 -1.81691891 0.212004658 -0.764237089 -1.720575785 -0.004080548 FBgn0035574 RhoGEF64C Rho guanine nucleotide exchange factor at 64C http://flybase.org/reports/FBgn0035574 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from genetic interaction with Rho1 "axon guidance ; GO:0007411 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from genetic interaction with Rho1 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from genetic interaction with Rho1" apical cortex ; GO:0045179 | inferred from direct assay "CG32239, GEF64C, EP(3)3035, EP3035, CG13710, CG13709, RhoGEF64C, Gef64C, RhoGEF, GEF(64C), GEF, RhoGef64C" "IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG32239 11-Aug-17 DroID_v2017_08 "Drer\arhgef3, Drer\itsn2b, Drer\itsn2a, Drer\arhgef16, Drer\ngef, Drer\net1, Drer\arhgef3l, Drer\si:dkey-91i10.2, Drer\itsn1" "Scer\ROM2, Scer\ROM1, Scer\TUS1" "Cele\ephx-1, Cele\rhgf-1, Cele\Y95B8A.12" "Xtro\arhgef3.1, Xtro\itsn1, Xtro\arhgef16, Xtro\itsn2, Xtro\net1, Xtro\arhgef3.2" "Mmus\Itsn2, Mmus\Itsn1, Mmus\Net1, Mmus\Arhgef15, Mmus\Arhgef3, Mmus\Arhgef26, Mmus\Plekhg6, Mmus\Arhgef16, Mmus\Arhgef10l, Mmus\Kalrn, Mmus\Ngef" "Hsap\ITSN2, Hsap\ARHGEF1, Hsap\NGEF, Hsap\ITSN1, Hsap\KALRN, Hsap\PLEKHG6, Hsap\ARHGEF15, Hsap\ARHGEF28, Hsap\NET1, Hsap\ARHGEF3, Hsap\ARHGEF16, Hsap\ARHGEF18" embryonic stage " embryonic central nervous system

,

ubiquitous " "viable,neuroanatomy defective,behavior defective,recessive,long lived,starvation stress response defective,temperature response defective,gravitaxis defective,male limited,fertile,visible,partially lethal - majority die,some die during pupal stage" "ventral nerve cord commissure,longitudinal connective,commissure,eye,actin filament & embryonic/larval tracheal systembtl.PS,mesothoracic tergum" DRSC08319 K -0.147860124 -0.752479413 -0.605524131 0.337786363 0.540863757 2.51310002 FBgn0261268 Cul3 Cullin 3 http://flybase.org/reports/FBgn0261268 protein_coding_gene "ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Roc1a, Roc1b ubiquitin-protein transferase activity ; GO:0004842 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VFP2 ubiquitin protein ligase activity ; GO:0061630 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000231993" "sensory organ development ; GO:0007423 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred by curator from GO:0031463,GO:0031625 axonogenesis ; GO:0007409 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | non-traceable author statement sleep ; GO:0030431 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000231993 compound eye morphogenesis ; GO:0001745 | non-traceable author statement protein ubiquitination ; GO:0016567 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype" Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from physical interaction with klhl10 female germline ring canal ; GO:0035324 | colocalizes_with inferred from direct assay inferred from physical interaction with kel Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG42616, cul3, CUL3, CG11861, gft/dCul-3, Cul3, Cul-3, dCul3, dCul-3, DMcul-3, BG:DS07851.2, l(2)35Cd, l(2)br34, l35Cd, br34, l(2)06430, mds, CG31829, gft, cul-3, guftagu, CUL-3, Cullin3, Cullin 3" "IPR001373:Cullin, N-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016157:Cullin, conserved site, IPR016158:Cullin homology, IPR016159:Cullin repeat-like-containing domain, IPR019559:Cullin protein, neddylation domain" CG42616 11-Aug-17 DroID_v2017_08 "Drer\cul4b, Drer\cul3a, Drer\cul3b, Drer\cacul1, Drer\cul4a" "Scer\CDC53, Scer\CUL3" "Cele\cul-1, Cele\cul-3, Cele\cul-2, Cele\cul-4, Cele\cul-6" "Xtro\cul4a, Xtro\cul4b, Xtro\cul3" "Mmus\Cul4b, Mmus\Cul4a, Mmus\Cacul1, Mmus\Cul3" "Hsap\CUL4A, Hsap\CUL3, Hsap\CACUL1, Hsap\CUL4B" "some die during embryonic stage,recessive,locomotor rhythm defective,male fertile,male sterile,partially,lethal - all die before end of embryonic stage,lethal - all die before end of larval stage,some die during larval stage,lethal,germline clone,maternal effect,visible,somatic clone,neuroanatomy defective,sleep defective,partially lethal - majority die,viable,RU486 conditional" "dorsal appendage,germline clone,maternal effect,egg,wing,somatic clone,wing vein,wing vein L3,sensillum campaniformium of dorsal radius,ectopic,sensillum campaniformium,wing hair,external sensory organ,microchaeta,macrochaeta,trichogen cell,sensory mother cell,cell autonomous,wing disc,neuron & mushroom body,spermatid,nurse cell ring canal,filamentous actin,neuron & beta-lobe,neuron & gamma-lobe,neuron & alpha-lobe,wing vein L4,anterior crossvein,mesothoracic tergum & macrochaeta-4512,scutellum & macrochaeta-4512,sensillum campaniformium & wing-4512,wing margin bristle" FBgn0003973 ven venation http://flybase.org/reports/FBgn0003973 - gene - - - ven - - 11-Aug-17 DroID_v2017_08 - - - - - - "small body,sterile" "wing vein,wing vein L3,crossvein,eye,macrochaeta" FBgn0259669 B0942 - http://flybase.org/reports/FBgn0259669 gene - - - B0942 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,unguis,arista,anterior crossvein" FBgn0035458 ppk27 pickpocket 27 http://flybase.org/reports/FBgn0035458 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG10858, ppk27" IPR001873:Epithelial sodium channel CG10858 11-Aug-17 DroID_v2017_08 "Drer\asic1c, Drer\asic1b, Drer\asic4a, Drer\asic1a, Drer\asic2, Drer\asic4b" - "Cele\del-8, Cele\acd-4, Cele\acd-2, Cele\acd-3, Cele\acd-1, Cele\delm-2, Cele\delm-1, Cele\del-6, Cele\flr-1" "Xtro\asic1, Xtro\asic4, Xtro\scnn1d, Xtro\scnn1b, Xtro\scnn1g, Xtro\asic5, Xtro\scnn1a" "Mmus\Asic2, Mmus\Scnn1a, Mmus\Asic3, Mmus\Scnn1g, Mmus\Asic4, Mmus\Asic1, Mmus\Asic5, Mmus\Scnn1b" "Hsap\SCNN1B, Hsap\ASIC2, Hsap\ASIC1, Hsap\SCNN1D, Hsap\SCNN1A, Hsap\ASIC3, Hsap\ASIC5, Hsap\SCNN1G, Hsap\ASIC4" "partially lethal - majority die,some die during pupal stage,viable" FBgn0004643 Zw10 Zeste-white 10 http://flybase.org/reports/FBgn0004643 "FBgn0000016, FBgn0002765, FBgn0029627, FBtr0070441, FBpp0070425" protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with rod, Zwilch Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab18" mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000258496 membrane addition at site of cytokinesis ; GO:0007107 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | traceable author statement mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype cleavage furrow ingression ; GO:0036090 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred from sequence or structural similarity with SGD:S000005202 Golgi organization ; GO:0007030 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR009361 kinetochore microtubule ; GO:0005828 | inferred from direct assay Dsl1/NZR complex ; GO:0070939 | inferred from sequence or structural similarity with SGD:S000005202 kinetochore ; GO:0000776 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000005202 RZZ complex ; GO:1990423 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay Golgi stack ; GO:0005795 | inferred from direct assay acroblast ; GO:0036063 | inferred from direct assay RZZ complex ; GO:1990423 | inferred from physical interaction with rod, Zwilch condensed chromosome outer kinetochore ; GO:0000940 | non-traceable author statement" "zw10, ZW10, Zw10, ZW-10, EG:BACR7C10.3, CG9900, mit(l)15, dZW10, zw-10, l(1)zw10, abe, l(1)6-99, l(1)3Af, mit(1)15, Mit(1)15, Dsl1" "IPR009361:RZZ complex, subunit Zw10" CG9900 11-Aug-17 DroID_v2017_08 Drer\zw10 - Cele\czw-1 Xtro\zw10 Mmus\Zw10 Hsap\ZW10 " embryonic stage--pupal stage , adult stage | female " " larval stage | third instar , embryonic stage | syncytial blastoderm , spermatogenesis && adult stage , embryonic stage | 0-16 hr " " onion stage spermatid

, spermatocyte

" "cytokinesis defective,meiotic cell cycle defective,lethal,recessive,male sterile,partially lethal - majority die,polyphasic,mitotic cell cycle defective,female sterile,visible,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,viable,male fertile,wild-type,heat sensitive,neuroanatomy defective" "scutellar bristle,anterior vertical bristle,posterior vertical bristle,spermatid,Nebenkern,nuclear chromosome | embryonic stage | germline clone,eye,wing,wing vein,dorsocentral bristle,ocellar bristle,anterior orbital bristle,middle orbital bristle,posterior orbital bristle,spermatozoon,testis,onion stage spermatid,egg,germline clone,maternal effect,female reproductive system,macrochaeta & thorax,macrochaeta & head,nucleus | embryonic stage | germline clone,Golgi stack,contractile ring,spindle,cleavage furrow,acroblast,neuroblast,wing vein L4,secondary spermatocyte,spermatocyte,meiotic cell cycle,mitotic anaphase,nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0010382 CycE Cyclin E http://flybase.org/reports/FBgn0010382 "FBgn0001984, FBgn0010318, FBgn0015389, FBgn0022237" protein_coding_gene cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from sequence or structural similarity cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with mi protein binding ; GO:0005515 | inferred from physical interaction with brm inferred from physical interaction with Snr1 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype regulation of DNA replication ; GO:0006275 | inferred from mutant phenotype cell proliferation involved in compound eye morphogenesis ; GO:0035736 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement G1/S transition of mitotic cell cycle ; GO:0000082 | traceable author statement G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype positive regulation of G1/S transition of mitotic cell cycle ; GO:1900087 | inferred from mutant phenotype G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype negative regulation of ubiquitin protein ligase activity ; GO:1904667 | inferred from genetic interaction with Rca1 neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype sensory organ precursor cell division ; GO:0045035 | inferred from mutant phenotype somatic stem cell population maintenance ; GO:0035019 | inferred from direct assay JAK-STAT cascade ; GO:0007259 | inferred from genetic interaction with hop pole cell development ; GO:0007277 | inferred from expression pattern regulation of exit from mitosis ; GO:0007096 | inferred from genetic interaction with CycA inferred from genetic interaction with fzr ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of protein phosphorylation ; GO:0001932 | inferred from direct assay neuron fate specification ; GO:0048665 | inferred from direct assay positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from expression pattern cell adhesion ; GO:0007155 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CycE, CyclE, DmCycE, cycE, cyclinE, DmcycE, Cyc E, D-CycE, fond, BG:DS07108.3, l(2)35Dd, CyeE, l(2)k05007, l(2)k02602, l(2)br37, DmcyclinE, l35Dd, br37, CDI7, l(2)k02514, l(2)05206, cdi7, Cdi7, CG3938, dCycE, CYCE, dm-cycE, cycline, 3938, CycEI, Cyc" "IPR004367:Cyclin, C-terminal domain, IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like, IPR028858:Cyclin E" CG3938 11-Aug-17 DroID_v2017_08 "Drer\ccne2, Drer\ccne1" "Scer\CLB3, Scer\CLB2, Scer\CLB6, Scer\CLB1, Scer\CLB5, Scer\CLB4" Cele\cye-1 "Xtro\ccne1, Xtro\ccne2" "Mmus\Ccne2, Mmus\Ccne1" "Hsap\CCNE2, Hsap\CNTD2, Hsap\CCNE1" " embryonic stage | stage >=10 , embryonic stage , embryonic stage | early , embryonic stage | stage 5 , embryonic stage | stage >10 , embryonic stage | stage 8-11 , embryonic stage | 1-2hr " " Malpighian tubule | restricted

, epidermis | dorsal

, organism | striped

, peripheral nervous system | restricted

, embryonic central nervous system | restricted

, embryonic/larval hindgut

, embryonic central nervous system

, neuroblast

, peripheral nervous system

, anterior embryonic/larval midgut

,

posterior , posterior embryonic/larval midgut

" " larval stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage " " eye-antennal disc | restricted

, lamina anlage

, oocyte

, nurse cell

, larval inner optic anlage

, morphogenetic furrow | posterior to

, larval outer optic anlage

, follicle cell

" "visible,viable,female sterile,neuroanatomy defective,recessive,lethal,lethal - all die during embryonic stage,lethal - all die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,mitotic cell cycle defective,partially,lethal - all die before end of larval stage,sterile,some die during larval stage,fertile,meiotic cell cycle defective,size defective,heat sensitive,homeotic,increased cell number,somatic clone,decreased cell size,wild-type,increased cell death" "neuroblast NB6-4 of thorax,glial cell,ectopic,eye,neuroblast NB6-4a,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,wing vein,ommatidium,ventral nerve cord commissure,macrochaeta,heterochromatin & nurse cell,nurse cell & nucleus,nurse cell,egg chamber,germinal vesicle,oocyte,dorsal appendage,cystocyte,anterior midgut proper primordium & mitotic cell cycle,wing vein L5,larval outer optic anlage,wing,distal,posterior,interommatidial bristle,pigment cell,eye photoreceptor cell,eye disc,wing hair,follicle stem cell,somatic clone,egg,chorion,mitotic cell cycle | ectopic | heat sensitive,extended germ band embryo,heat sensitive,embryonic epidermis,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,eye-antennal disc,S phase | ectopic,morphogenetic furrow,anterior,embryo,wing cell,RP2 motor neuron,neuroblast NB4-2,ganglion mother cell,embryonic hindgut,neuroblast NB6-4 of abdomen,mitotic cell cycle | embryonic stageprd.RG1,G1 phase & external sensory organ precursor cell IIIbneur-P72,tormogen cell,thecogen cell,neuron & embryonic abdomen | ectopic-537.4,glial cell & eye disc | ectopicbi-omb-Gal4,embryonic/larval salivary gland,follicle cell & nucleus | somatic clone,S phase | ectopicF4,larval salivary gland & embryo & nucleusF4,embryonic segment,posterior compartment,wing blade,aCC neuron,pCC neuron,embryonic/larval salivary gland | embryonic stage,presumptive embryonic salivary gland,ommatidial precursor cluster,adult brain,tracheole,cell non-autonomous,macrochaeta & thorax,neuroblast NB6-4" DRSC03295 IEK -4.699781408 -5.940046543 -1.197202356 -5.348837529 7.114616203 7.56278251 FBgn0010328 woc without children http://flybase.org/reports/FBgn0010328 FBgn0039502 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR010507 protein binding ; GO:0005515 | inferred from physical interaction with HP1c protein binding ; GO:0005515 | inferred from physical interaction with row inferred from physical interaction with HP1c RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000192346 chromatin binding ; GO:0003682 | contributes_to inferred from physical interaction with row DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000192346" "ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" "polytene chromosome interband ; GO:0005705 | inferred from direct assay protein complex ; GO:0043234 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN000192346 heterochromatin ; GO:0000792 | inferred from direct assay euchromatin ; GO:0000791 | inferred from direct assay euchromatin ; GO:0000791 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000192346 polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay" "CG5965, woc, Woc, WOC" "IPR010507:Zinc finger, MYM-type, IPR011017:TRASH domain, IPR021893:Protein of unknown function DUF3504" CG5965 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-173p18.3, Drer\si:ch211-266o15.1, Drer\qrich1, Drer\zmym2, Drer\zmym4" - - "Xtro\zmym3, Xtro\zmym2, Xtro\zmym4, Xtro\qrich1.2, Xtro\qrich1.1" "Mmus\Zmym5, Mmus\Zmym3, Mmus\Qrich1, Mmus\Zmym2, Mmus\Zmym1, Mmus\Zmym6, Mmus\Zmym4" "Hsap\ZMYM3, Hsap\QRICH1, Hsap\ZMYM6, Hsap\ZMYM1, Hsap\ZMYM2, Hsap\ZMYM5, Hsap\TMEM35B, Hsap\ZMYM4" "lethal,recessive,viable,fertile,partially lethal - majority die,sterile,visible,female fertile,wild-type,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,female semi-sterile,lethal - all die before end of larval stage,some die during third instar larval stage" "ring gland,prothoracic gland,nuclear chromosome,hemocyte,embryonic/larval lymph gland,imaginal disc,embryonic/larval brain,embryonic/larval proventriculus,wing,wing vein,eye,chromosome, telomeric region,ganglion mother cell,trichogen cell,polytene chromosome,chromosome, telomeric regionmbtP)" FBgn0002921 Atpalpha Na pump alpha subunit http://flybase.org/reports/FBgn0002921 "FBgn0004667, FBgn0010739, FBgn0010749, FBgn0011344, FBgn0011348, FBgn0011389, FBgn0011518, FBgn0014319, FBgn0024511, FBgn0038844" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR005775 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250 cation transmembrane transporter activity ; GO:0008324 | contributes_to inferred from direct assay sodium:potassium-exchanging ATPase activity ; GO:0005391 | inferred from mutant phenotype sodium:potassium-exchanging ATPase activity ; GO:0005391 | contributes_to inferred from mutant phenotype sodium:potassium-exchanging ATPase activity ; GO:0005391 | inferred from sequence or structural similarity with RGD:2167 "potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR005775 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR005775 adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from direct assay response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype jump response ; GO:0007630 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype response to temperature stimulus ; GO:0009266 | inferred from mutant phenotype tissue homeostasis ; GO:0001894 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from direct assay regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype neuromuscular process ; GO:0050905 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype regulation of tube architecture, open tracheal system ; GO:0035152 | traceable author statement" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR005775 plasma membrane ; GO:0005886 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay septate junction ; GO:0005918 | inferred from direct assay sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred by curator from GO:0005391 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay" "Atpalpha, ATPalpha, Na[+]/K[+] ATPase, ATPBagr, Na[+]K[+]ATPase, Na[+], K[+] -ATPase, NaK ATPase, ATPa, Atp a, CG5670, Na,K-ATPase, Na+-K+-ATPase, Na[+]/K[+]ATPase, Na[+],K[+]-ATPase, Na[+],K[+]-ATPase alpha-subunit, Na[+],K[+]-ATPase alpha subunit, Na[+]-K[+]-ATPase alpha[[5]]-subunit, Na[+]/K[+]-ATPase, Na/K-ATPase alpha-subunit, Na/K-ATPase, Na,K ATPase, sodium/potassium transporting ATPase alpha, Na+/K+ ATPase alpha subunit, Da-47, l(3)01164, l(3)04492, l(3)ry136, l(3)rM454, l(3)j6A4, l(3)j3B7, l(3)j3B2, l(3)01453, Na-p, JY, dnATPase, atpalpha, NaK, Atpa, Na[+]K[+] ATPase, ATP-alpha, Na[+]K[+]-ATPase, (Na[+]/k[+])-ATPase, Na/K ATPase" "IPR018303:P-type ATPase, phosphorylation site, IPR001757:P-type ATPase, IPR004014:Cation-transporting P-type ATPase, N-terminal, IPR005775:P-type ATPase, subfamily IIC, IPR006068:Cation-transporting P-type ATPase, C-terminal, IPR008250:P-type ATPase, A domain, IPR023214:HAD-like domain, IPR023298:P-type ATPase, transmembrane domain, IPR023299:P-type ATPase, cytoplasmic domain N" CG5670 11-Aug-17 DroID_v2017_08 "Drer\atp1a1a.5, Drer\atp1a1a.1, Drer\atp1a3b, Drer\atp1a2a, Drer\atp1a1a.2, Drer\atp1a3a, Drer\atp1a1a.3, Drer\atp1a1a.4, Drer\atp1a1b" "Scer\PMA1, Scer\PMR1" "Cele\catp-4, Cele\catp-3, Cele\catp-1, Cele\eat-6, Cele\catp-2" "Xtro\atp1a1, Xtro\atp1a2, Xtro\atp4a, Xtro\atp12a, Xtro\atp1a3" "Mmus\Atp1a2, Mmus\Atp1a4, Mmus\Atp1a3, Mmus\Atp12a, Mmus\Atp1a1, Mmus\Atp4a" "Hsap\ATP4A, Hsap\ATP1A4, Hsap\ATP12A, Hsap\ATP1A1, Hsap\ATP1A2, Hsap\ATP1A3" " larval stage , embryonic stage -- adult stage , adult stage " " embryonic/larval salivary gland

, abdomen

, larval brain

, head

, thorax

, Malpighian tubule

, adult head

, adult thorax

" adult stage " adult brain

, indirect flight muscle

, thoracico-abdominal ganglion

, optic lobe

, retina

, photoreceptor cell

, Malpighian tubule

, tubular muscle

" "lethal,bang sensitive,dominant,locomotor behavior defective,partially lethal - majority die,neuroanatomy defective,viable,heat sensitive,long lived,short lived,locomotor rhythm defective,fertile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,paralytic,neurophysiology defective,chemical sensitive,hypoactive,conditional,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority live,fully,rescuable maternal effect,cold sensitive,phototaxis defective,chemical resistant,partially,behavior defective,circadian behavior defective,auditory perception defective" "adult brain,thoracico-abdominal ganglion,flight muscle,neuromuscular junction,NMJ bouton,supernumerary,embryonic/first instar larval cuticle,segment,embryonic segment,septate junction,presumptive embryonic/larval tracheal system,ganglionic branch primordium,dorsal trunk primordium,dorsal medial muscle,embryonic/larval dorsal trunk,embryonic/larval ganglionic branch,presumptive embryonic salivary gland,embryonic somatic muscle,tracheal branch primordium,Malpighian tubule,Johnston organ" FBgn0039044 p53 p53 http://flybase.org/reports/FBgn0039044 protein_coding_gene "ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with Ubc6 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95SP2 RNA polymerase II transcription factor binding ; GO:0001085 | inferred from physical interaction with UniProtKB:Q9V4D4 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000154790 damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000154790 transcription factor binding ; GO:0008134 | inferred from physical interaction with bip2 ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with sip3 TFIIH-class transcription factor binding ; GO:0001097 | inferred from physical interaction with mrn p53 binding ; GO:0002039 | inferred from biological aspect of ancestor with PANTHER:PTN000154790 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Daxx core promoter binding ; GO:0001047 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000154790" "intrinsic apoptotic signaling pathway in response to DNA damage=0008630 | <> negative regulation of photoreceptor cell differentiation=0046533 |...<> negative regulation of transcription factor import into nucleus=0042992 |...<> intrinsic apoptotic signaling pathway by p53 class mediator=0072332 |...<> cellular response to DNA damage stimulus=0006974 |...<> regulation of transcription from RNA polymerase II promoter=0006357 |...<> positive regulation of multicellular organism growth=0040018 |...<> oogenesis=0048477 |... with okr <> response to starvation=0042594 |...<> negative regulation of phosphatidylinositol 3-kinase activity=0043553 |...<> reciprocal meiotic recombination=0007131 |...<> intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator=0042771 |...<> response to ionizing radiation=0010212 |...<> positive regulation of transcription, DNA-templated=0045893 |... <> negative regulation of transcription from RNA polymerase II promoter=0000122 |... biological aspect of ancestor with PANTHER:PTN000154790 <> regulation of apoptosis involved in tissue homeostasis=0060785 |...<> regulation of organ growth=0046620 |...<> response to UV=0009411 |...<> cellular response to starvation=0009267 |...<> positive regulation of transcription from RNA polymerase II promoter=0045944 |... biological aspect of ancestor with PANTHER:PTN000154790 <> positive regulation of macroautophagy=0016239 |...<> regulation of transcription from RNA polymerase II promoter in response to DNA damage=1990248 |...<> response to radiation=0009314 |...<> regulation of neuron apoptotic process=0043523 |... biological aspect of ancestor with PANTHER:PTN000154790 <> intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator=0042771 | <> intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator=0042771 |... with UniProtKB:P25153 <> positive regulation of cell cycle=0045787 |... with COX5A <> ectopic germ cell programmed cell death=0035234 |...<> neuroblast differentiation=0014016 |...<> DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator=0006978 |... biological aspect of ancestor with PANTHER:PTN000154790 <> cellular response to gamma radiation=0071480 |...<> DNA damage response, signal transduction by p53 class mediator=0030330 | <> neuroblast proliferation=0007405 |...<> positive regulation of transcription, DNA-templated=0045893 |...<> regulation of DNA repair=0006282 |...<> cellular response to UV=0034644 |... biological aspect of ancestor with PANTHER:PTN000154790 <> activation of cysteine-type endopeptidase activity involved in apoptotic process=0006919 |...<> determination of adult lifespan=0008340 |...<> cell death=0008219 |...<> regulation of cell proliferation=0042127 |...<> positive regulation of cellular response to X-ray=2000685 |...<> regulation of transcription from RNA polymerase II promoter=0006357 | <> positive regulation of transcription from RNA polymerase II promoter=0045944 |...<> intrinsic apoptotic signaling pathway in response to DNA damage=0008630 |...<> response to radiation=0009314 | <> apoptotic process=0006915 | <> negative regulation of multicellular organism growth=0040015 |... with RIOK2 <> positive regulation of insulin-like growth factor receptor signaling pathway=0043568 |...<> negative regulation of peptide hormone secretion=0090278 |...<> cellular response to DNA damage stimulus=0006974 |... <> positive regulation of growth rate=0040010 |...<> tissue regeneration=0042246 |...<> mitotic G1 DNA damage checkpoint=0031571 |... biological aspect of ancestor with PANTHER:PTN000154790 <> apoptotic process=0006915 |... mutant phenotype" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000154790 nucleus ; GO:0005634 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | colocalizes_with inferred from direct assay transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000154790 chromocenter ; GO:0010369 | colocalizes_with inferred from direct assay "Dmp53, dp53, DmP53, dmp53, prac, Dm-P53, CG10873, CG33336, CG31325, p53, Dp53, DMP53, D-p53, P53" "IPR008967:p53-like transcription factor, DNA-binding, IPR011615:p53, DNA-binding domain, IPR012346:p53/RUNT-type transcription factor, DNA-binding domain, IPR024631:Transcription factor p53, C-terminal, Drosophila, IPR002117:p53 tumour suppressor family" CG33336 11-Aug-17 DroID_v2017_08 "Drer\tp53, Drer\tp73, Drer\tp63" - - "Xtro\tp63, Xtro\tp53, Xtro\tp73" "Mmus\Trp53, Mmus\Trp63, Mmus\Trp73" "Hsap\TP63, Hsap\TP73, Hsap\TP53" " adult stage && oogenesis stage | stage S10 , embryonic stage | stage 10 , adult stage | female , embryonic stage -- adult stage , embryonic stage | stage 16 , embryonic stage , adult stage , larval stage " " oocyte

, embryonic/larval foregut

, nurse cell

, mesoderm

, germline cell

, embryonic/larval hindgut

, embryonic/larval hindgut | restricted

, embryonic/larval midgut

" "viable,fertile,visible,increased cell death,decreased cell number,germline clone,hyperplasia,lethal - all die before end of pupal stage,decreased cell death,radiation resistant,long lived,RU486 conditional,chemical resistant,conditional,female,neuroanatomy defective,wild-type,mitotic cell cycle defective,size defective,lethal,somatic clone,increased cell size,cell death defective,radiation sensitive,short lived,chemical sensitive,recessive,sterile,partially,aging defective,partially lethal - majority die" "eye,wing,ommatidium,interommatidial bristle,ovary,germline cell,egg chamber,wing disc,oocyte,pole cell,posterior compartment,conditional,neuroblast | larval stage,eye disc,posterior,photoreceptor cell R7,cone cell,posterior | third instar larval stage,photoreceptor cell R7 | third instar larval stage,somatic clone,mitochondrion | somatic clone,embryonic/larval neuroblast,outer photoreceptor cell,neuroblast" FBgn0040068 Vav Vav guanine nucleotide exchange factor http://flybase.org/reports/FBgn0040068 protein_coding_gene Rac guanyl-nucleotide exchange factor activity ; GO:0030676 | inferred from direct assay regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 actin filament organization ; GO:0007015 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype activation of GTPase activity ; GO:0090630 | inferred from direct assay cell adhesion ; GO:0007155 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype regulation of adherens junction organization ; GO:1903391 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from direct assay central nervous system development ; GO:0007417 | inferred from genetic interaction with Sos inferred from genetic interaction with trio cellular_component ; GO:0005575 | no biological data available "Vav, DroVav, CG7893, BcDNA:GH01128, vav, DmVav" "IPR000219:Dbl homology (DH) domain, IPR000980:SH2 domain, IPR001452:SH3 domain, IPR001715:Calponin homology domain, IPR001849:Pleckstrin homology domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR011993:PH domain-like" CG7893 11-Aug-17 DroID_v2017_08 "Drer\stac3, Drer\vav2, Drer\spata13, Drer\arhgef4, Drer\arhgef9a, Drer\pex13, Drer\arhgef9b, Drer\prex1, Drer\vav3b" "Scer\CDC24, Scer\PEX13" "Cele\Y37A1B.17, Cele\tiam-1, Cele\uig-1, Cele\vav-1, Cele\prx-13" "Xtro\vav2, Xtro\vav3, Xtro\stac2, Xtro\vav1, Xtro\stac3" "Mmus\Vav3, Mmus\Spata13, Mmus\Vav1, Mmus\Stac2, Mmus\Vav2, Mmus\Prex1, Mmus\Pex13, Mmus\Stac3, Mmus\Plekhg1, Mmus\Plekhg2, Mmus\Arhgef9, Mmus\Arhgef4, Mmus\Plekhg3, Mmus\Stac" "Hsap\ARHGEF4, Hsap\ARHGEF9, Hsap\STAC3, Hsap\VAV1, Hsap\STAC, Hsap\SPATA13, Hsap\PLEKHG1, Hsap\PREX1, Hsap\PLEKHG3, Hsap\STAC2, Hsap\VAV2, Hsap\PEX13, Hsap\PLEKHG2, Hsap\VAV3" "neuroanatomy defective,cell migration defective,visible,lethal,recessive,female limited,partially lethal - majority die,male limited,locomotor behavior defective,some die during pupal stage,immune response defective" "embryonic/larval epidermis | embryonic stage,embryonic myoblast,longitudinal connective | embryonic stage,embryonic/larval peripheral nervous system | embryonic stage,longitudinal visceral muscle primordium,embryonic/larval dorsal trunk | embryonic stage,embryonic/larval dorsal branch | embryonic stage,eye,longitudinal connective,midline crossing tract,photoreceptor,lamina,medulla,ellipsoid body,male limited,somatic clone,trichogen cell" FBgn0262332 mir-968 mir-968 stem loop http://flybase.org/reports/FBgn0262332 miRNA_gene - - - "mir-968, miR-968, CR43039" - CR43039 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing | pharate adult stage,wing,mesothoracic tergum" FBgn0032600 BuGZ Bub3 interacting GLEBS and Zinc finger domain protein http://flybase.org/reports/FBgn0032600 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000575874 mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000575875 mitotic spindle assembly checkpoint ; GO:0007094 | inferred from biological aspect of ancestor with PANTHER:PTN000575875 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype attachment of spindle microtubules to kinetochore ; GO:0008608 | inferred from biological aspect of ancestor with PANTHER:PTN000575875 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000575873 kinetochore ; GO:0000776 | inferred from biological aspect of ancestor with PANTHER:PTN000575875 spindle matrix ; GO:1990047 | inferred from biological aspect of ancestor with PANTHER:PTN000575875 "BcDNA:LD27810, CG17912, lincRNA.S1359, Dm_2L:87597, BuGZ" "IPR003656:Zinc finger, BED-type, IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG17912 11-Aug-17 DroID_v2017_08 "Drer\znf207a, Drer\znf207b" - Cele\B0035.1 Xtro\znf207 Mmus\Zfp207 Hsap\ZNF207 "neuroanatomy defective,partially lethal - majority die,some die during pupal stage" ventral multidendritic neuron vdaB DRSC02642 E 0.820141082 -0.820133766 0.254625491 -2.534114865 -0.589687324 0.424317235 FBgn0069096 nap napoleon http://flybase.org/reports/FBgn0069096 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available nap - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic abdomen,germline clone,maternal effect,embryo,posterior" FBgn0032006 Pvr PDGF- and VEGF-receptor related http://flybase.org/reports/FBgn0032006 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement vascular endothelial growth factor-activated receptor activity ; GO:0005021 | inferred from sequence or structural similarity with HGNC:3763 transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from sequence or structural similarity with HGNC:8803 protein binding ; GO:0005515 | inferred from physical interaction with Cbl, spri protein binding ; GO:0005515 | inferred from physical interaction with Crk" antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | traceable author statement border follicle cell migration ; GO:0007298 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype positive regulation of MAPK cascade ; GO:0043410 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | traceable author statement vascular endothelial growth factor receptor signaling pathway ; GO:0048010 | inferred from sequence or structural similarity with HGNC:3763 protein phosphorylation ; GO:0006468 | non-traceable author statement Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype hemocyte proliferation ; GO:0035172 | traceable author statement larval lymph gland hemopoiesis ; GO:0035167 | inferred from genetic interaction with bip1 imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Egfr inferred from genetic interaction with Cbl intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype hemocyte development ; GO:0007516 | inferred from mutant phenotype cellular response to insulin stimulus ; GO:0032869 | inferred from mutant phenotype hemopoiesis ; GO:0030097 | inferred from expression pattern TORC1 signaling ; GO:0038202 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:3763 inferred from sequence or structural similarity with HGNC:8803 plasma membrane ; GO:0005886 | inferred from direct assay "VEGFR, PVR, pvr, CG8222, VEGFR-A, Vegfr-c, Vegfr-b, stai, Vegfr, DmVEGFR, vgr1, VGR1, CT24332, Vgr1, Pvr, Vegf, 8222, PvR" "IPR000719:Protein kinase domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold, IPR017441:Protein kinase, ATP binding site, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR013098:Immunoglobulin I-set" CG8222 11-Aug-17 DroID_v2017_08 "Drer\pdgfra, Drer\pdgfrb, Drer\csf1rb, Drer\fgfr3, Drer\pdgfrl, Drer\fgfr1a, Drer\fgfrl1a, Drer\fgfr4, Drer\ret, Drer\flt4, Drer\styk1, Drer\kdr, Drer\si:dkey-14o18.6, Drer\kitb, Drer\flt3, Drer\kita, Drer\si:ch211-167j9.5, Drer\si:zfos-1069f5.1, Drer\tie1, Drer\fgfrl1b, Drer\flt1, Drer\csf1ra, Drer\kdrl, Drer\si:ch73-206d17.1, Drer\LOC569566, Drer\tek, Drer\fgfr2" Scer\SKM1 "Cele\Y50D4B.6, Cele\old-2, Cele\ver-4, Cele\old-1, Cele\kin-30, Cele\R09D1.13, Cele\kin-15, Cele\kin-23, Cele\ver-3, Cele\W04G5.10, Cele\kin-9, Cele\ver-1, Cele\F09G2.1, Cele\R09D1.12" "Xtro\fgfrl1, Xtro\pdgfrl.2, Xtro\ret, Xtro\fgfr1, Xtro\pdgfrl, Xtro\tek, Xtro\kdr, Xtro\pdgfra, Xtro\flt4, Xtro\kdrl, Xtro\tie1, Xtro\csf1r, Xtro\flt1, Xtro\fgfr2, Xtro\fgfr3, Xtro\fgfr4, Xtro\styk1" "Mmus\Fgfr1, Mmus\Fgfr4, Mmus\Styk1, Mmus\Dscam, Mmus\Pdgfrl, Mmus\Kdr, Mmus\Tie1, Mmus\Kit, Mmus\Fgfrl1, Mmus\Csf1r, Mmus\Pdgfrb, Mmus\Flt4, Mmus\Ceacam20, Mmus\Fgfr2, Mmus\Pdgfra, Mmus\Tek, Mmus\Fgfr3, Mmus\Ret, Mmus\Flt3, Mmus\Flt1" "Hsap\CD22, Hsap\FCRL2, Hsap\FGFR3, Hsap\TIE1, Hsap\CEACAM20, Hsap\PDGFRL, Hsap\FLT1, Hsap\FGFRL1, Hsap\KDR, Hsap\SIGLEC1, Hsap\KIT, Hsap\PDGFRA, Hsap\TEK, Hsap\FLT4, Hsap\FGFR2, Hsap\STYK1, Hsap\PDGFRB, Hsap\FGFR1, Hsap\FLT3, Hsap\RET, Hsap\CSF1R, Hsap\FGFR4" " embryonic stage | stage >8 , embryonic stage , larval stage , embryonic stage | stage 11-13 " " embryonic hemocyte

, ventral midline

restricted , larval hemocyte

, embryonic trachea

" " embryonic stage | stage 16 , adult stage " " midline glial cell | subset

, follicle cell

, embryonic hemocyte

" "increased cell death,lethal,recessive,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,somatic clone,temperature conditional,decreased cell size,neuroanatomy defective,tumorigenic,immune response defective,partially,lethal - all die before end of pupal stage,some die during pupal stage,visible,partially lethal - majority die" "Kc167 cell-line,embryonic hemocyte,macrophage,border follicle cell,hemocyte,somatic clone,embryonic/larval hemocyte,ventral nerve cord,embryonic anterior Malpighian tubule,thorax,intestinal stem cell,temperature conditional,enteroblast of posterior adult midgut epithelium,longitudinal connective,embryonic/larval glial cell,presumptive embryonic/larval central nervous system,actin filament | ectopicslbo.2.6,centripetally migrating follicle cell,centripetally migrating follicle cell & actin filamentslbo.2.6,follicle cell,follicle cell & actin filament | somatic clone,hemocyte | larval stage,melanotic mass,lamellocyte,embryonic/first instar larval cuticle,wing disc | larval stage,ventral nerve cord | embryonic stage,border follicle cell & filopodiumslbo.2.6,male terminalia,adult external abdomen,dorsal,male genitalia,dorsal mesothoracic disc & actin filamentptc-559.1,dorsal mesothoracic disc & actin filament & pupa | ectopicBx-MS1096,wing,mesothoracic tergum,microchaeta,actin filament | ectopic,cortical actin cytoskeleton & oocyte associated follicle cellslbo.2.6,adult midgut,enteroendocrine cell,supernumerary,enterocyte,dorsal mesothoracic disc & actin filament | ectopicdpp.blk1,wing disc,trichogen cell,plasmatocyte | third instar larval stage,crystal cell | third instar larval stage" DRSC03080 IEK -3.774866373 -8.350750738 -8.966135791 2.42315247 1.951037086 2.523491109 FBgn0028671 Vha100-1 Vacuolar H[+] ATPase 100kD subunit 1 http://flybase.org/reports/FBgn0028671 protein_coding_gene "photoreceptor activity ; GO:0009881 | inferred from mutant phenotype calmodulin binding ; GO:0005516 | inferred from direct assay ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000005796 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000179505" "response to light stimulus ; GO:0009416 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype intracellular pH reduction ; GO:0051452 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence or structural similarity with SGD:S000005796 autophagosome maturation ; GO:0097352 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 endosomal lumen acidification ; GO:0048388 | NOT inferred from mutant phenotype ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" "synapse ; GO:0045202 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay vacuolar proton-transporting V-type ATPase complex ; GO:0016471 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000005796" "vha100-1, CG1709, BcDNA:LD21248, Vha100-1, v100, V100, v0a1, vha, V0, Vha100, V0a" "IPR002490:V-type ATPase, V0 complex, 116kDa subunit family, IPR026028:ATPase, V0 complex, subunit 116kDa, eukaryotic" CG1709 11-Aug-17 DroID_v2017_08 "Drer\atp6v0a2b, Drer\tcirg1a, Drer\tcirg1b, Drer\atp6v0a1a, Drer\atp6v0a2a, Drer\atp6v0a1b, Drer\si:ch73-173p19.2" "Scer\VPH1, Scer\STV1" "Cele\vha-5, Cele\unc-32, Cele\vha-6, Cele\vha-7" "Xtro\atp6v0a4, Xtro\atp6v0a1, Xtro\atp6v0a2, Xtro\tcirg1" "Mmus\Atp6v0a2, Mmus\Atp6v0a4, Mmus\Atp6v0a1, Mmus\Tcirg1" "Hsap\ATP6V0A2, Hsap\ATP6V0A1, Hsap\ATP6V0A4, Hsap\TCIRG1" "visible,phototaxis defective,somatic clone,neurophysiology defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,germline clone,conditional,lethal,viable" "eye,eye photoreceptor cell,synaptic vesicle & eye photoreceptor cell | somatic clone,eye photoreceptor cell & synapse | somatic clone,photoreceptor cell,rhabdomere | conditional" FBgn0002623 M(3)96C Minute (3) 96C http://flybase.org/reports/FBgn0002623 - gene - - - "M(3)be, M(3R)be, M(3)36e, M(3)96C" - - 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,dominant,visible,Minute" "macrochaeta,posterior crossvein,wing,wing vein L2" FBgn0013723 pfy puffy http://flybase.org/reports/FBgn0013723 - gene - - - pfy - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,female,sex-determination defective,viable,male" "female genitalia,prothoracic leg,female,sex comb,ectopic,polytene chromosome | male" FBgn0001432 l(1)7Ab lethal (1) 7Ab http://flybase.org/reports/FBgn0001432 - gene - - - "l(1)jnR2, jnR2, l(1)7Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0002812 ms(1)V1 male sterile (1) V1 http://flybase.org/reports/FBgn0002812 - gene - - - ms(1)V1 - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0000953 Fs(2)Dor Female sterile (2) Dorog http://flybase.org/reports/FBgn0000953 - gene - - - "Dorog, Fs(2)Sz3, Fs(2)Dor" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile germline-dependent,dominant" dorsal appendage FBgn0264639 curlicue curlicue http://flybase.org/reports/FBgn0264639 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - curlicue - - 11-Aug-17 DroID_v2017_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0011656 Mef2 Myocyte enhancer factor 2 http://flybase.org/reports/FBgn0011656 "FBgn0010437, FBgn0019710, FBgn0047353" protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR019503 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR002100 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from electronic annotation with InterPro:IPR033896 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0001205 | inferred from mutant phenotype enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay" MAPK cascade ; GO:0000165 | inferred from electronic annotation with InterPro:IPR033896 myoblast fusion ; GO:0007520 | inferred from mutant phenotype skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype anterior midgut development ; GO:0007496 | inferred from mutant phenotype muscle fiber development ; GO:0048747 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from mutant phenotype carbohydrate storage ; GO:0052576 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype regulation of striated muscle tissue development ; GO:0016202 | traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern lipid storage ; GO:0019915 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay ovarian follicle cell development ; GO:0030707 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "MEF-2, dmef2, D-Mef2, Dmef2, mef2, dMef2, DMef2, dMEF2, DMEF2, DMedf2, Dmef, D-MEF2, D-mef2, MEF2, SD04091, mef-2, mef, Dmef-2, DMef-2, Mef, DMEF-2, C, 22.21, BEST:SD04091, CG1429, l(2)46CFr, Mef2, mb247, Mef-2, mef2c, dMEf2" "IPR002100:Transcription factor, MADS-box, IPR033896:MADS MEF2-like, IPR022102:Holliday junction regulator protein family C-terminal, IPR019503:Peptidase M66 domain" CG1429 11-Aug-17 DroID_v2017_08 "Drer\mef2ca, Drer\mef2b, Drer\mef2aa, Drer\mef2cb, Drer\mef2d, Drer\srfb" "Scer\SMP1, Scer\RLM1" Cele\mef-2 "Xtro\mef2c, Xtro\mef2a, Xtro\mef2d" "Mmus\Mef2c, Mmus\Mef2a, Mmus\Mef2d, Mmus\2310045n01rik-mef2b, Mmus\Mef2b" "Hsap\MEF2A, Hsap\BORCS8-MEF2B, Hsap\BORCS8, Hsap\MEF2C, Hsap\MEF2B, Hsap\MEF2D" " embryonic stage , embryonic stage | stage 13 , embryonic stage | stage >10 , embryonic stage | late , embryonic stage | stage 10 , embryonic stage | stage 5 , embryonic stage -- adult stage , adult stage , embryonic stage | stage 5-9 , embryonic stage | extended germ band , embryonic stage | stage 6,7 " " cardioblast

, embryonic/larval heart

, embryonic somatic muscle

, visceral mesoderm

, embryonic visceral muscle

, embryonic visceral muscle | precursor

, larval visceral muscle

, pharyngeal muscle | precursor

, embryonic somatic muscle | precursor

, somatic mesoderm

,

pair rule , embryonic/larval dorsal vessel

, mesoderm

, mesoderm | primordium

, ventral furrow

, embryonic/larval somatic muscle

, embryonic fat body

, pericardial cell

" " embryonic stage | stage 6 , embryonic stage | extended germ band , embryonic stage | late , embryonic stage | mid , embryonic stage | stage >=11 , embryonic stage | stage >=10 , embryonic stage | stage 13 , embryonic stage | stage 6-10 , embryonic stage | stage 14 " " ventral furrow

, mesoderm

, pharyngeal muscle

, somatic mesoderm

, head mesoderm

, cardioblast

, visceral mesoderm

, visceral muscle

, larval visceral muscle

, embryonic/larval somatic muscle

, embryonic/larval dorsal vessel

, embryonic myoblast

, somatic muscle

, embryonic/larval heart

, mesoderm | segmentally repeated

" "lethal,partially,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,short lived,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,locomotor rhythm defective,heat sensitive,flightless,viable,female sterile,polyphasic,partially lethal - majority die,flight defective" "embryonic/larval muscle system,gastric caecum primordium,adult somatic muscle,mesothoracic extracoxal depressor muscle 66,dorsal medial muscle | pupal stage,indirect flight muscle | pupal stage,embryonic/larval cardial cell,embryonic/larval somatic muscle,embryonic/larval midgut,embryonic visceral muscle,muscle fiber,myoblast,muscle founder cell,embryonic myoblast,neuromuscular junction | embryonic stage,tormogen cell,presumptive embryonic/larval muscle system,heat sensitive,lateral transverse muscle,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,embryonic/larval dorsal vessel,dorsal medial muscle,coxal tergal remotor muscle,lateral oblique dorsal muscle,tergosternal muscle,somatic muscle,embryonic/larval heart,intersegmental nerve,pharyngeal muscle,midgut constriction,muscle attachment site,A1-7 dorsal acute muscle 1,egg,dorsal appendage,centripetally migrating follicle cell,oblique muscle,anterior embryonic/larval midgut,gastric caecum,denticle belt,embryonic/first instar larval cuticle,dorsal closure embryo,trachea,embryonic epidermis,embryonic/larval midgut | embryonic stage,cardioblast,embryonic/larval pericardial cell,A1-7 lateral transverse muscle,A1-7 lateral transverse muscle 4,eye,adult head,antenna,wing,trichogen cell,mesothoracic tergum" FBgn0021750 SerRS-m "Seryl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0021750 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002314, InterPro:IPR002317 serine-tRNA ligase activity ; GO:0004828 | inferred from mutant phenotype serine-tRNA ligase activity ; GO:0004828 | traceable author statement" mitochondrial seryl-tRNA aminoacylation ; GO:0070158 | inferred from mutant phenotype seryl-tRNA aminoacylation ; GO:0006434 | traceable author statement cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002317 mitochondrion ; GO:0005739 | traceable author statement "Aat-Ser, SerRS, seryl-tRNA synthetase, SRS, CG4938, DmSRS2, Aats-ser, SerRS-m" "IPR002314:Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR002317:Serine-tRNA ligase, type1, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR033729:Serine-tRNA ligase catalytic core domain" CG4938 11-Aug-17 DroID_v2017_08 "Drer\sars2, Drer\sars" "Scer\DIA4, Scer\SES1" "Cele\sars-2, Cele\sars-1" "Xtro\sars2, Xtro\sars" "Mmus\Sars2, Mmus\Sars" "Hsap\SARS2, Hsap\FBXO17, Hsap\SARS" embryonic stage embryonic/larval salivary gland

"lethal,visible,heat sensitive,short lived,locomotor behavior defective" "wing,1st posterior cell,anterior crossvein,mitochondrion, with Dcr-2UAS.cDa, ,mitochondrial matrix, with Dcr-2UAS.cDa, ,mitochondrial crista, with Dcr-2UAS.cDa, " FBgn0000180 bib big brain http://flybase.org/reports/FBgn0000180 - protein_coding_gene cation channel activity ; GO:0005261 | inferred from direct assay channel activity ; GO:0015267 | inferred from sequence or structural similarity with Drip water transmembrane transporter activity ; GO:0005372 | NOT inferred from direct assay ion channel activity ; GO:0005216 | NOT inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from mutant phenotype nervous system development ; GO:0007399 | non-traceable author statement ovarian follicle cell development ; GO:0030707 | traceable author statement ectoderm development ; GO:0007398 | traceable author statement single organismal cell-cell adhesion ; GO:0016337 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from sequence or structural similarity with Drip regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 adherens junction ; GO:0005912 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Drip "Bib, EP(2)2278, BIB_DROME, m-bib, l(2)neo91, l(2)neo66, CG4722, bib" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR022357:Major intrinsic protein, conserved site, IPR023271:Aquaporin-like" CG4722 11-Aug-17 DroID_v2017_08 "Drer\aqp8a.2, Drer\mipa, Drer\mipb, Drer\aqp1a.1, Drer\aqp8b, Drer\aqp4, Drer\aqp8a.1, Drer\aqp3a, Drer\aqp1a.2, Drer\si:dkey-30h22.11, Drer\aqp3b" "Scer\YLL053C, Scer\YFL054C, Scer\AQY1, Scer\AQY2" "Cele\aqp-2, Cele\aqp-6, Cele\aqp-4, Cele\aqp-7, Cele\aqp-8" "Xtro\fam188b, Xtro\LOC100216133, Xtro\LOC100489792, Xtro\aqp2, Xtro\aqp8, Xtro\mip, Xtro\aqp5" "Mmus\Aqp8, Mmus\Aqp1, Mmus\Aqp6, Mmus\Fam188b, Mmus\Aqp7, Mmus\Aqp2, Mmus\Mip, Mmus\Aqp4, Mmus\Aqp3, Mmus\Aqp5" "Hsap\MIP, Hsap\AQP3, Hsap\AQP6, Hsap\AQP7, Hsap\AQP8, Hsap\AQP1, Hsap\AQP5, Hsap\AQP4, Hsap\FAM188B2, Hsap\AQP2, Hsap\AQP9" " embryonic stage | stage 5 , embryonic stage | stage 9-12 , embryonic stage | stage 5-12 " " organism | ubiquitous

, mesoderm

, organism

, ectoderm | restricted

" " embryonic stage | stage 13-15 , embryonic stage | stage 7 , larval stage | third instar , pupal stage | 24 hr , embryonic stage | stage 13 , embryonic stage | stage >=7 , embryonic stage | stage 11 , embryonic stage | stage 16 " " posterior embryonic/larval midgut

, amnioproctodeal invagination

, proneural cluster &&of dorsal mesothoracic disc

, eo neuron

, tormogen cell

, stomodeal invagination

, embryonic/larval dorsal vessel

, ectoderm

, epidermis

, ventral midline

, trichogen cell

, Malpighian tubule

, pupal epidermis

, sense organ &&of dorsal mesothoracic disc

, flight muscle | precursor

, embryonic/larval tracheal pit

, ventral nervous system | subset

, wing vein | precursor

, thecogen cell

, amnioserosa

, adepithelial cell of dorsal mesothoracic disc | restricted

, adult myoblast | precursor

" "visible,lethal,neurogenic phenotype,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,neuroanatomy defective,viable,body color defective,size defective" "scutellar bristle,ectopic,macrochaeta,embryonic epidermis,eye photoreceptor cell,somatic clone,supernumerary,rhabdomere | somatic clone | supernumerary,multidendritic neuron,embryonic/larval dorsal vessel,precursor,embryonic/larval salivary gland,embryonic Malpighian tubule,stomatogastric nervous system,optic lobe,embryonic/larval somatic muscle,neuroblast,cardioblast,sensory mother cell,peripheral glial cell,presumptive embryonic/larval central nervous system,microchaeta,presumptive embryonic/larval nervous system,embryonic myoblast,embryonic/larval nervous system,embryonic/larval oenocyte precursor,nervous system,ventral,embryonic/first instar larval cuticle,ectoderm,germline clone,sense organ,chaeta,mesothoracic tergum,wing,posterior" FBgn0000719 fog folded gastrulation http://flybase.org/reports/FBgn0000719 "FBan0009559, FBgn0069907, FBgn0069908, FBgn0069909, FBtr0077342, FBpp0077034" protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with mthl1 "wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from genetic interaction with tor regulation of myosin II filament organization ; GO:0043519 | inferred from mutant phenotype regulation of development, heterochronic ; GO:0040034 | inferred from mutant phenotype mesoderm development ; GO:0007498 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype gastrulation ; GO:0007369 | traceable author statement ventral furrow formation ; GO:0007370 | inferred from mutant phenotype mitochondrial fission ; GO:0000266 | inferred from mutant phenotype actin-mediated cell contraction ; GO:0070252 | inferred from direct assay morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype posterior midgut invagination ; GO:0007374 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | non-traceable author statement torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor mesectoderm development ; GO:0048383 | inferred from mutant phenotype apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay nervous system development ; GO:0007399 | inferred from mutant phenotype" extracellular region ; GO:0005576 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity "l(1)16-3-190, l(1)114, l114, 114, M67, CR41110, CR41109, CR41108, l(1)20Ba, CG9559, fog, Fog" "IPR031761:Folded gastrulation, N-terminal domain" CG9559 11-Aug-17 DroID_v2017_08 "Drer\necap1, Drer\necap2" - Cele\Y110A2AR.3 Xtro\necap2 "Mmus\Necap2, Mmus\Necap1" Hsap\NECAP2 " embryonic stage | stage 6 , embryonic stage | stage 5 " "

posterior , posterior midgut proper primordium

,

ventral , ventral furrow

,

dorsal ,

0-10% egg length " "some die during first instar larval stage,some die during second instar larval stage,lethal - all die before end of larval stage,neuroanatomy defective,wild-type,cell migration defective,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,partially,developmental rate defective,viable,visible" "posterior embryonic/larval midgut,interface glial cell,glial cell projectionrepo,segmental nerve branch SNa of A1-7,fascicle,embryonic/larval central nervous system,motor neuron,glial cell projectionhtl.POS,embryonic head,dorsal,embryo,lateral,ventral furrow,amnioproctodeal invagination,salivary gland,mesoderm,embryonic/larval hindgut,Malpighian tubule,extended germ band embryo,posterior endoderm,posterior midgut primordium,presumptive embryonic salivary gland,endoderm,ventral midline,hub cell,adherens junctionmat.‘±Tub67C.THsimVP16,wing disc,wing,chaeta,supernumerary,mesothoracic tergum" FBgn0015222 Fer1HCH Ferritin 1 heavy chain homologue http://flybase.org/reports/FBgn0015222 "FBgn0010717, FBgn0011426, FBgn0039762, FBgn0043793" protein_coding_gene "ferric iron binding ; GO:0008199 | inferred from electronic annotation with InterPro:IPR001519, InterPro:IPR008331 ferrous iron binding ; GO:0008198 | non-traceable author statement ferrous iron binding ; GO:0008198 | inferred from direct assay iron ion binding ; GO:0005506 | inferred from biological aspect of ancestor with PANTHER:PTN000153092" detoxification of iron ion ; GO:1990461 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from direct assay intracellular sequestering of iron ion ; GO:0006880 | inferred from biological aspect of ancestor with PANTHER:PTN000153092 sleep ; GO:0030431 | inferred from expression pattern response to fungus ; GO:0009620 | inferred from expression pattern cellular iron ion homeostasis ; GO:0006879 | inferred from direct assay iron ion import into cell ; GO:0097459 | inferred from mutant phenotype cellular iron ion homeostasis ; GO:0006879 | non-traceable author statement post-embryonic development ; GO:0009791 | inferred from mutant phenotype fusome ; GO:0045169 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay intracellular ferritin complex ; GO:0008043 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000153092 extracellular region ; GO:0005576 | inferred from direct assay intracellular ferritin complex ; GO:0008043 | non-traceable author statement Golgi apparatus ; GO:0005794 | inferred from direct assay "CG2216, FerHCH, FER1, T21, T9, HCH, 1HCH, Fer1, l(3)00451, Fer-L, l(3)j10B4, BEST:LD36673, Fer1HCH, Fe1HCH, fer1hch, Fer1HC, FER1HCH, fer1" "IPR001519:Ferritin, IPR008331:Ferritin/DPS protein domain, IPR009040:Ferritin-like diiron domain, IPR009078:Ferritin-like superfamily, IPR012347:Ferritin-related" CG2216 11-Aug-17 DroID_v2017_08 "Drer\zgc:194125, Drer\LOC558816, Drer\zgc:92066, Drer\zgc:198419, Drer\fth1a, Drer\zgc:56095, Drer\zgc:172145, Drer\fth1b, Drer\zgc:173593" - "Cele\ftn-2, Cele\ftn-1" "Xtro\MGC76132, Xtro\ftmt, Xtro\fth1" "Mmus\Fth1, Mmus\Fthl17f, Mmus\Gm813, Mmus\Ftl1, Mmus\Fthl17d, Mmus\Fthl17a, Mmus\Fthl17e, Mmus\E330017A01Rik, Mmus\Ftmt, Mmus\Fthl17c, Mmus\Fthl17b" "Hsap\FTMT, Hsap\FTH1, Hsap\FTL, Hsap\FTHL17" "lethal,recessive,female fertile,germline clone,developmental rate defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority live,small body,visible,partially lethal - majority die,some die during pupal stage,circadian rhythm defective,gravitaxis defective,progressive,locomotor rhythm defective" "trichogen cell,mesothoracic tergum" FBgn0027948 msps mini spindles http://flybase.org/reports/FBgn0027948 protein_coding_gene microtubule plus-end binding ; GO:0051010 | inferred from biological aspect of ancestor with PANTHER:PTN000288762 tubulin binding ; GO:0015631 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with NCBI_gi:2136282 protein binding ; GO:0005515 | inferred from physical interaction with tacc cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from biological aspect of ancestor with PANTHER:PTN000288762 endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from biological aspect of ancestor with PANTHER:PTN000288762 establishment or maintenance of neuroblast polarity ; GO:0045196 | inferred from mutant phenotype female meiotic division ; GO:0007143 | traceable author statement mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype positive regulation of microtubule nucleation ; GO:0090063 | inferred from direct assay oogenesis ; GO:0048477 | inferred from mutant phenotype establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from biological aspect of ancestor with PANTHER:PTN000288762 mitotic nuclear division ; GO:0007067 | traceable author statement female meiotic division ; GO:0007143 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype pronuclear fusion ; GO:0007344 | inferred from mutant phenotype bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity with NCBI_gi:2136282 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype microtubule polymerization ; GO:0046785 | inferred from biological aspect of ancestor with PANTHER:PTN000288762 axon guidance ; GO:0007411 | inferred from mutant phenotype kinetochore ; GO:0000776 | inferred from biological aspect of ancestor with PANTHER:PTN000288762 centrosome ; GO:0005813 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000288762 spindle pole ; GO:0000922 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity with NCBI_gi:2136282 microtubule plus-end ; GO:0035371 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN000288762 centrosome ; GO:0005813 | traceable author statement microtubule plus-end ; GO:0035371 | inferred from direct assay spindle pole ; GO:0000922 | inferred from biological aspect of ancestor with PANTHER:PTN000288762 "msps, TOG, XMAP215, Dis1, Msps, CG5000, anon-WO0140519.136, MSPS" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024395:CLASP N-terminal domain, IPR034085:TOG domain, IPR021133:HEAT, type 2" CG5000 11-Aug-17 DroID_v2017_08 Drer\ckap5 Scer\STU2 "Cele\zyg-9, Cele\T08D2.8, Cele\F54A3.2" Xtro\ckap5 Mmus\Ckap5 Hsap\CKAP5 "size defective,heat sensitive,neuroanatomy defective,female sterile,viable,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,mitotic cell cycle defective,partially lethal - majority die,visible" "retina,heat sensitive,MP1 neuron,lateral longitudinal fascicle,intersegmental nerve branch ISNb of A1-7,nurse cell & microtubule,oocyte & microtubule,follicle cell & microtubule,oocyte,microtubule & nurse cell | oogenesis stage S8,microtubule & nurse cell | oogenesis stage S9,microtubule & nurse cell | oogenesis stage S10B,microtubule & oocyte | oogenesis stage S10B,oocyte nucleus,mitotic cell cycle,mitotic anaphase,mitotic anaphase & nuclear chromosome,mitotic cell cycle & spindle,cytoplasmic microtubule & embryonic/larval hemocyte,spindle,spindle pole,cytoplasmic microtubule,pronucleus,eye,macrochaeta,adult cuticle & abdomen,oocyte & spindle,mesothoracic tergum" FBgn0262446 mir-137 mir-137 stem loop http://flybase.org/reports/FBgn0262446 miRNA_gene - - - "miR-137, dme-mir-318, mir-137, MIR-137, CR43012, CR33575, 2R:11128979, dme-mir-137" - CR43012 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die" "wing vein,wing margin,wing" FBgn0013563 Pex1 Peroxin 1 http://flybase.org/reports/FBgn0013563 "FBgn0024587, FBgn0026223, FBgn0028085, FBgn0036409, FBgn0046338, FBgn0046339, FBgn0046340, FBgn0046489, FBgn0046490, FBgn0046491" protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from electronic annotation with InterPro:IPR025653 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960, InterPro:IPR015342, InterPro:IPR025653" protein targeting to peroxisome ; GO:0006625 | inferred from electronic annotation with InterPro:IPR025653 spermatocyte division ; GO:0048137 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8850 central nervous system development ; GO:0007417 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype peroxisomal membrane ; GO:0005778 | inferred from electronic annotation with InterPro:IPR025653 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8850 "DmCAB51031.1, l(3)084807, l(3)02402, l(3)s4868, l(3)S084807, 0848/07, anon-WO0172774.98, CG6760, anon-WO0172774.99, anon-WO0172774.96, anon-WO0172774.102, anon-WO0172774.101, anon-WO0172774.100, PEX1, pex1, l(3)70Da, Pex1, DmelPex1" "IPR025653:Peroxisome biogenesis factor 1, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR009010:Aspartate decarboxylase-like domain, IPR015342:Peroxisome biogenesis factor 1, N-terminal, psi beta-barrel fold, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR029067:CDC48 domain 2-like" CG6760 11-Aug-17 DroID_v2017_08 Drer\pex1 Scer\PEX1 "Cele\Y53F4B.9, Cele\prx-1" Xtro\pex1 Mmus\Pex1 Hsap\PEX1 "lethal,recessive,cytokinesis defective,meiotic cell cycle defective,body size defective,locomotor behavior defective,developmental rate defective,feeding behavior defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,increased cell death,partially lethal - majority die,viable" "spermatid,testis,ventral nerve cord,peripheral nervous system,central nervous system,eye-antennal disc primordium,embryonic brain,Malpighian tubule primordium,anterior spiracle primordium,posterior spiracle primordium,embryonic/larval glial cell,embryonic/larval salivary gland" FBgn0002344 l(3)87Bm lethal (3) 87Bm http://flybase.org/reports/FBgn0002344 - gene - - - "l(3)ck25, l(3)87Bm" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0011327 Uch-L5 Ubiquitin carboxy-terminal hydrolase L5 http://flybase.org/reports/FBgn0011327 "FBgn0027061, FBgn0028558" protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR001578 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 protein deubiquitination ; GO:0016579 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay "p37A, uch-L3, dUCH37, l(3)j2B8, BcDNA.LD24440, UCH, CG3431, BcDNA:LD24440, Uch-L3, UCH 37, Uch-L5, Uch37, Q9XZ61, uch-l5, uchl3, Uchl3" "IPR001578:Peptidase C12, ubiquitin carboxyl-terminal hydrolase, IPR017390:Ubiquitinyl hydrolase, UCH37 type" CG3431 11-Aug-17 DroID_v2017_08 "Drer\bap1, Drer\uchl5" - Cele\ubh-4 "Xtro\uchl5, Xtro\bap1" "Mmus\Bap1, Mmus\Uchl5" "Hsap\UCHL5, Hsap\BAP1" "lethal,short lived,lethal - all die before end of pupal stage,some die during pupal stage,recessive,partially lethal - majority die,visible,neuroanatomy defective,viable" "eye,wing hair,wing,tarsal segment & joint & pharate adult,leg,fourth segment of antenna,arista,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0060597 l(3)S092006b lethal (3) S092006b http://flybase.org/reports/FBgn0060597 gene - - - "0920/06, l(3)S092006b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0030574 CG9413 - http://flybase.org/reports/FBgn0030574 protein_coding_gene antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 L-amino acid transmembrane transporter activity ; GO:0015179 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000208210 CG9413 IPR002293:Amino acid/polyamine transporter I CG9413 11-Aug-17 DroID_v2017_08 "Drer\slc7a11, Drer\slc7a8b, Drer\slc7a10a, Drer\slc7a10b, Drer\si:dkeyp-120h9.1, Drer\zmp:0000001267, Drer\slc7a5, Drer\slc7a8a, Drer\slc7a7, Drer\slc7a6, Drer\si:ch73-352p4.8, Drer\slc7a9, Drer\slc7a14a" "Scer\LYP1, Scer\GNP1, Scer\TAT1, Scer\BAP3, Scer\MMP1, Scer\MUP1, Scer\MUP3" "Cele\F23F1.6, Cele\aat-1, Cele\aat-4, Cele\aat-2, Cele\aat-3, Cele\B0454.6, Cele\aat-5" "Xtro\slc7a6, Xtro\slc7a15, Xtro\slc7a13, Xtro\slc7a11, Xtro\slc7a10, Xtro\slc7a9, Xtro\slc7a7, Xtro\LOC100492274, Xtro\slc7a5, Xtro\slc7a8" "Mmus\Slc7a9, Mmus\Slc7a5, Mmus\Slc7a8, Mmus\Slc7a15, Mmus\Slc7a12, Mmus\Slc7a6, Mmus\Slc7a7, Mmus\Slc7a11, Mmus\Slc7a13, Mmus\Slc7a14, Mmus\Slc7a10" "Hsap\SLC7A9, Hsap\SLC7A14, Hsap\SLC7A11, Hsap\SLC7A7, Hsap\SLC7A5, Hsap\SLC7A6, Hsap\SLC7A10, Hsap\SLC7A8, Hsap\SLC7A13" "viable,fertile,lethal,recessive" FBgn0027977 l(3)S139101 lethal (3) S139101 http://flybase.org/reports/FBgn0027977 gene - - - "1391/01, l(3)S139101" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0004138 l(2)43Eg lethal (2) 43Eg http://flybase.org/reports/FBgn0004138 - gene - - - l(2)43Eg - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0003206 Ras64B Ras oncogene at 64B http://flybase.org/reports/FBgn0003206 FBgn0063029 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849 protein binding ; GO:0005515 | inferred from physical interaction with Rgl" Ras protein signal transduction ; GO:0007265 | inferred from sequence or structural similarity with MGI:MGI:1914172 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available "ras, Ras, Dras2, Ras2, ras2, DRas2, RAS, Dras64B, ras-2, D-ras2, c-ras2, D-ras-2, Dmras64B, Dm-ras-64B, CG1167, C-ras2, BcDNA:RE36103, Ras64B, RAS2, RAS64B" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR020849:Small GTPase superfamily, Ras type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1167 11-Aug-17 DroID_v2017_08 "Drer\gem, Drer\ralba, Drer\rap1b, Drer\rhebl1, Drer\ralbb, Drer\rap2ab, Drer\rasl11a, Drer\zgc:110699, Drer\diras1b, Drer\kras, Drer\zgc:171704, Drer\hrasa, Drer\rap2b, Drer\rap1ab, Drer\nras, Drer\si:ch73-116o1.2, Drer\diras2, Drer\zgc:152698, Drer\ralab, Drer\rap1aa, Drer\rras2, Drer\zgc:64022, Drer\rasd1, Drer\rras, Drer\si:dkey-27j5.5, Drer\zgc:55558, Drer\rasl12, Drer\rem1, Drer\rheb, Drer\diras1a, Drer\hrasb, Drer\rem2, Drer\rsg1, Drer\LOC103909873, Drer\ralaa, Drer\rit1, Drer\rerglb, Drer\rrad, Drer\mras, Drer\zgc:114118, Drer\rergla, Drer\si:dkeyp-59c12.1, Drer\zgc:153845, Drer\rasl11b, Drer\rasl10a, Drer\LOC100332969, Drer\rap2c" "Scer\RAS2, Scer\RHB1, Scer\RAS1, Scer\RSR1" "Cele\ras-2, Cele\ras-1, Cele\ral-1, Cele\rap-1, Cele\let-60, Cele\C44B7.12" "Xtro\ralb, Xtro\rem2, Xtro\rasd1, Xtro\rheb, Xtro\diras3, Xtro\rit1, Xtro\rem1, Xtro\rap2a, Xtro\adal, Xtro\rerg, Xtro\rras, Xtro\LOC733456, Xtro\rap1b, Xtro\LOC100485959, Xtro\ras-dva, Xtro\rsg1, Xtro\rala, Xtro\rhebl1, Xtro\rap2b, Xtro\diras1, Xtro\hras, Xtro\kras, Xtro\rasl10a, Xtro\rasd2, Xtro\rergl, Xtro\rasl11b, Xtro\rrad, Xtro\rap1a, Xtro\nras, Xtro\rap2c, Xtro\gem, Xtro\diras2" "Mmus\Rrad, Mmus\Rasl10b, Mmus\Eras, Mmus\Nras, Mmus\Rap1a, Mmus\Rit1, Mmus\Diras2, Mmus\Rem2, Mmus\Rit2, Mmus\Rras, Mmus\Adal, Mmus\Kras, Mmus\Rem1, Mmus\Rap2a, Mmus\Mras, Mmus\Ralb, Mmus\Gm266, Mmus\Rras2, Mmus\Diras1, Mmus\Rasl11b, Mmus\Rasl11a, Mmus\Gem, Mmus\Rergl, Mmus\Rala, Mmus\Rap1b, Mmus\Rasl10a, Mmus\Rasd1, Mmus\Rap2b, Mmus\Rap2c, Mmus\Rsg1, Mmus\Rhebl1, Mmus\Hras, Mmus\Rasl12, Mmus\Rasd2, Mmus\Rheb, Mmus\Rerg" "Hsap\KRAS, Hsap\RALB, Hsap\RHEB, Hsap\RAP1A, Hsap\RALA, Hsap\RERGL, Hsap\RASL10A, Hsap\RRAS, Hsap\MRAS, Hsap\RASD1, Hsap\DIRAS1, Hsap\ERAS, Hsap\RASD2, Hsap\RAP2A, Hsap\RIT2, Hsap\RRAD, Hsap\RASL11B, Hsap\GEM, Hsap\RAP1B, Hsap\RERG, Hsap\DIRAS2, Hsap\RAP2C, Hsap\REM1, Hsap\RASL10B, Hsap\NRAS, Hsap\RASL11A, Hsap\REM2, Hsap\RIT1, Hsap\RAP2B, Hsap\HRAS, Hsap\RRAS2, Hsap\RASL12, Hsap\RHEBL1, Hsap\RSG1, Hsap\DIRAS3" " adult stage , larval stage | third instar , embryonic stage " " adult brain | resticted

, dorsal mesothoracic disc

, thoracico-abdominal ganglion

, eye-antennal disc

, garland cell

, embryonic central nervous system

, antenno-maxillary complex

, larval brain | restricted

, genital disc

" "lethal,maternal effect,visible,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,cell polarity defective,female,lethal - all die before end of pupal stage,some die during pupal stage,small body,heat sensitive,viable" "ommatidium,maternal effect,dorsal triple row,medial triple row,ventral triple row,anterior sternopleural bristle,middle sternopleural bristle,posterior sternopleural bristle,ventral sternopleural bristle,upper humeral bristle,lower humeral bristle,humeral sclerite,ventral wing blade,dorsal wing blade,embryonic head,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,eye,photoreceptor cell,wing vein,ectopic,wing" DRSC08689 IE -0.179531449 -2.164211685 -2.53675042 -2.056523671 -0.520522795 -1.37855724 FBgn0069336 UY2635 UY2635 http://flybase.org/reports/FBgn0069336 gene - - - UY2635 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,viable" "mushroom body & axon7B,Kenyon cell,mushroom body & axonc739,mushroom body beta-lobe" FBgn0031057 Ubqn Ubiquilin http://flybase.org/reports/FBgn0031057 protein_coding_gene proteasome binding ; GO:0070628 | inferred from physical interaction with Rpn10 amyloid precursor protein metabolic process ; GO:0042982 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "clone 5.42, BEST:LD26923, anon-18DEa, Dsk2, Ubqn, CG14224, dUbqn, ubqn, dUbqln, DSK2, Chap, UBQLN homolog, UBQLN1" "IPR000626:Ubiquitin domain, IPR006636:Heat shock chaperonin-binding, IPR015940:Ubiquitin-associated domain, IPR009060:UBA-like, IPR015496:Ubiquilin, IPR029071:Ubiquitin-related domain" CG14224 11-Aug-17 DroID_v2017_08 Drer\ubqln4 Scer\DSK2 "Cele\ubql-1, Cele\F49C12.9" "Xtro\ubqln1, Xtro\ubqln4" "Mmus\Ubqlnl, Mmus\4931431F19Rik, Mmus\Ubqln3, Mmus\Ubqln4, Mmus\Ubqln2, Mmus\Ubqln1" "Hsap\UBQLN4, Hsap\UBQLN2, Hsap\UBQLN3, Hsap\UBQLNL, Hsap\UBQLN1" "lethal - all die before end of P-stage,some die during pharate adult stage,lethal,short lived,male limited,increased cell death,neuroanatomy defective,partially lethal - majority die,visible,viable" "air bubble | pharate adult stage,head | pharate adult stage,eye | pharate adult stage,leg | pharate adult stage,wing | pharate adult stage,wing vein,ectopic,neuropil,wing vein L4,wing vein L5,anterior crossvein,posterior crossvein,wing vein L3,wing margin,wing cell,wing,crossvein,eye photoreceptor cell,pigment cell,trichogen cell,mesothoracic tergum" FBgn0015989 l(2)PC4-S lethal (2) PC4-S http://flybase.org/reports/FBgn0015989 - gene - - - l(2)PC4-S - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0001689 l(1)ESHS10 lethal (1) ESHS10 http://flybase.org/reports/FBgn0001689 - gene - - - l(1)ESHS10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0005632 faf fat facets http://flybase.org/reports/FBgn0005632 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P09052 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | traceable author statement thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay protein deubiquitination ; GO:0016579 | traceable author statement germ cell migration ; GO:0008354 | traceable author statement protein deubiquitination ; GO:0016579 | inferred from direct assay ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from genetic interaction with Prosβ6 nuclear cortical migration ; GO:0035192 | inferred from mutant phenotype endocytosis ; GO:0006897 | non-traceable author statement mystery cell differentiation ; GO:0008583 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype inferred from genetic interaction with dpp inferred from genetic interaction with Med cellularization ; GO:0007349 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype negative regulation of proteolysis ; GO:0045861 | non-traceable author statement mystery cell differentiation ; GO:0008583 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG1945, BcDNA.LD22582, BcDNA:LD22582, faf, Faf, Fat, P55824, USPX" "IPR018200:Ubiquitin specific protease, conserved site, IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR011989:Armadillo-like helical, IPR028889:Ubiquitin specific protease domain, IPR016024:Armadillo-type fold" CG1945 11-Aug-17 DroID_v2017_08 "Drer\usp9, Drer\usp24" Scer\UBP15 Cele\T24B8.7 "Xtro\usp24, Xtro\usp34, Xtro\usp9x" "Mmus\Usp24, Mmus\Usp9y, Mmus\Usp9x, Mmus\Usp34" "Hsap\USP9Y, Hsap\USP24, Hsap\USP9X, Hsap\USP34" adult stage && oogenesis stage " nurse cell

, germarium

" " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S10 , larval stage , larval stage | third instar , oogenesis stage&&larval stage , larval stage&&spermatogenesis " " nurse cell

, oocyte | posterior

, eye-antennal disc

, morphogenetic furrow | anterior to

, ovary

, testis

, embryonic/larval digestive system

" "visible,neurophysiology defective,neuroanatomy defective,viable,recessive,female sterile,wild-type,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,partially lethal - majority die,maternal effect" "rhabdomere R7,dorsocentral bristle,trichogen cell,scutellar bristle,adult abdominal sensillum & trichogen cell-537.4,synapse,bouton,supernumerary,synapse | supernumerary,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,anterior fascicle & bouton,neuromuscular junction,wing sensillum,ectopic,adult mushroom body,eye,ommatidium,giant fiber neuron,tergotrochanteral muscle motor neuron,synapseOK307,synaptic vesicle,embryonic/larval central nervous system,neurite | pharate adult stage,embryonic/first instar larval cuticle,non-rescuable maternal effect,embryonic head,filzkorper,cone cell,eye photoreceptor cell,syncytial blastoderm embryo,maternal effect,denticle belt,eye photoreceptor cell & ommatidium | ectopic | somatic clone,denticle,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,pole cell" FBgn0001790 l(1)Mb15 lethal (1) Mb15 http://flybase.org/reports/FBgn0001790 - gene - - - l(1)Mb15 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053514 CG33514 - http://flybase.org/reports/FBgn0053514 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 neurogenesis ; GO:0022008 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "CG15018, CG15017, CG33514" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG33514 11-Aug-17 DroID_v2017_08 "Drer\sec14l7, Drer\sec14l8, Drer\ttpa, Drer\rlbp1a, Drer\rlbp1b, Drer\clvs2, Drer\ttpal" "Scer\SFH5, Scer\SEC14, Scer\YKL091C" - "Xtro\sec14l3, Xtro\rlbp1, Xtro\clvs2, Xtro\mospd2, Xtro\ttpa, Xtro\sec14l1, Xtro\sec14l5, Xtro\clvs1, Xtro\ttpal" "Mmus\Sec14l1, Mmus\Sec14l2, Mmus\Sec14l4, Mmus\Sec14l3, Mmus\Clvs1, Mmus\Clvs2, Mmus\Ttpa, Mmus\Sec14l5, Mmus\Rlbp1, Mmus\Ttpal" "Hsap\SEC14L5, Hsap\SEC14L6, Hsap\SEC14L2, Hsap\SEC14L1, Hsap\RLBP1, Hsap\CLVS1, Hsap\SEC14L4, Hsap\CLVS2, Hsap\TTPA, Hsap\SEC14L3, Hsap\TTPAL" "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval neuroblast,ganglion mother cell" DRSC08471 K -0.344285829 -0.857186342 0.641568006 -0.887781557 -1.677563834 -0.928097129 FBgn0014010 Rab5 Rab5 http://flybase.org/reports/FBgn0014010 FBgn0022048 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 protein binding ; GO:0005515 | inferred from physical interaction with hook inferred from physical interaction with Tbc1d15-17 inferred from physical interaction with CG6607 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Rbsn-5" "endosomal vesicle fusion ; GO:0034058 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | traceable author statement plasma membrane to endosome transport ; GO:0048227 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype establishment or maintenance of apical/basal cell polarity ; GO:0035088 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 synaptic vesicle to endosome fusion ; GO:0016189 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from genetic interaction with dsh mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of synapse structure or activity ; GO:0050803 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype synaptic vesicle to endosome fusion ; GO:0016189 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 endocytic vesicle ; GO:0030139 | inferred from biological aspect of ancestor with PANTHER:PTN000634566 lipid particle ; GO:0005811 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay early endosome ; GO:0005769 | non-traceable author statement early endosome ; GO:0005769 | "Rab5, Drab5, rab5, Dm Rab5, Rab, BAA88244, AAF51265, CG3664, DmRab5, DRab5, l(2)k08232, RAB5, dRab5, RAB5a, Rab-5, drab5" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3664 11-Aug-17 DroID_v2017_08 "Drer\rab5ab, Drer\rab24, Drer\rab5aa, Drer\rab20, Drer\rab31, Drer\rab5b, Drer\rab22a, Drer\rab5c, Drer\zgc:154045" "Scer\YPT53, Scer\YPT10, Scer\YPT52, Scer\VPS21" "Cele\rab-21, Cele\C56E6.2, Cele\rab-5" "Xtro\rab5c, Xtro\rab5b, Xtro\rab5a, Xtro\mras, Xtro\rab22a, Xtro\rab20, Xtro\rab24, Xtro\rab21" "Mmus\Rab17, Mmus\Rab21, Mmus\Rab5b, Mmus\Rab5c, Mmus\Rab20, Mmus\Rab5a, Mmus\Rab22a, Mmus\Rab24, Mmus\Rab31" "Hsap\RAB5A, Hsap\RAB20, Hsap\RAB31, Hsap\RAB5B, Hsap\RAB21, Hsap\RAB24, Hsap\RAB5C, Hsap\RAB17, Hsap\RAB22A" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "lethal,recessive,partially lethal - majority die,fertile,poor,flightless,locomotor behavior defective,meiotic cell cycle defective,dominant,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,paralytic,hyperplasia,somatic clone,large body,neuroanatomy defective,increased cell growth,lethal - all die before end of embryonic stage,some die during embryonic stage,neurophysiology defective,viable,increased cell death,body color defective" "crystal cell,synaptic vesicle & larval neuromuscular junction,mitosis & nuclear chromosome,endosomeneur-P72,sensory mother cell,external sensory organ precursor cell IIb,external sensory organ precursor cell IIa,supernumerary,adult cuticle,presumptive embryonic/larval nervous system,germline clone,endosome & embryonic nervous system,follicle cell,somatic clone,eye-antennal disc,eye disc,wing disc,yolk granule | germline clone,egg,endocytic vesicle | germline clone,dendrite | somatic clone | third instar larval stage,axon | somatic clone | third instar larval stage,eye photoreceptor cell,synapseGMR.PF,axon terminusGMR.PF,photoreceptor cell,synapsehs.PS,endosomehs.PS,photoreceptor cell & synaptic vesiclehs.PS,nerve terminal & synaptic vesicle,dendrite | third instar larval stageppk.1.9,axon | third instar larval stageppk.1.9,syncytial blastoderm embryo,synaptic vesiclehs.PS,nerve terminal & synaptic vesiclehs.PS,wing margin bristle,ectopic,egg chamber & basement membrane | apicalslbo.2.6,border follicle cell,polar follicle cell,endocytic vesicleslbo.2.6,wing,dendrite | third instar larval stageunspecified,axon | third instar larval stageunspecified,amnioserosa,embryonic dorsal epidermis,embryonic/larval dorsal trunk,NMJ bouton | third instar larval stage,NMJ bouton | adult stage,class IV dendritic arborizing neuron | third instar larval stage,endocytic vesicleunspecified,wing blade,posterior compartment,epithelium,female germline cyst,adult thorax,male genitalia,muscle tendon junctionMef2.PR,embryonic/larval neuromuscular junction,early endosomeCU1,wing hair,vesicleeg-Mz360,scutellar bristle,endosomeBx-MS1096,rhabdomereGMR.PF" DRSC00777 EK 0.807389352 -1.234961499 0.174691036 -5.995475044 0.209746363 -1.965172754 FBgn0034067 CG8399 - http://flybase.org/reports/FBgn0034067 protein_coding_gene ferric-chelate reductase activity ; GO:0000293 | inferred from direct assay oxidation-reduction process ; GO:0055114 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "anon-EST:ParkEST009, CG8399, SDR2, sdr2" "IPR002861:Reeler domain, IPR005018:DOMON domain, IPR006593:Cytochrome b561/ferric reductase transmembrane" CG8399 11-Aug-17 DroID_v2017_08 "Drer\zgc:163022, Drer\si:ch73-196i15.5, Drer\frrs1b, Drer\frrs1a, Drer\si:ch73-196i15.3, Drer\frrs1l" - "Cele\C29F5.8, Cele\M03A1.3, Cele\C09F9.2, Cele\Y57G11A.4, Cele\F23B12.4, Cele\C05D12.1, Cele\C13B4.1" Xtro\frrs1 "Mmus\Frrs1l, Mmus\Frrs1" "Hsap\FRRS1L, Hsap\FRRS1" "viable,visible" trichogen cell FBgn0000568 Eip75B Ecdysone-induced protein 75B http://flybase.org/reports/FBgn0000568 "FBgn0010914, FBgn0011342, FBgn0011386, FBgn0011430, FBgn0011438, FBgn0013628, FBgn0043377, FBgn0046398, FBgn0046399, FBgn0047288" protein_coding_gene "steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 thyroid hormone receptor activity ; GO:0004887 | inferred from electronic annotation with InterPro:IPR001728 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement heme binding ; GO:0020037 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 regulation of ecdysteroid metabolic process ; GO:0007553 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:7962 ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from direct assay antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype oogenesis ; GO:0048477 | non-traceable author statement response to ecdysone ; GO:0035075 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "E75, E75B, E75A, CG8127, l(3)07041, EP1121b, E75C, NR1D3, 57B, E75-C, DmE75B, DmE75A, l(3)neo25, dE75, l(3)j5E1, l(3)j3A6, l(3)j12E8, l(3)j11A6, Eip75, BcDNA:GM02640, anon-WO0172774.32, anon-WO0172774.31, Eip75B, EiP75, Eip75 A, eip75B, Eip75A, Mgn00274, Rev-Erb, 75B" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type, IPR001728:Thyroid hormone receptor" CG8127 11-Aug-17 DroID_v2017_08 "Drer\nr5a1a, Drer\thrab, Drer\nr1i2, Drer\nr2f5, Drer\nr2f6b, Drer\ar, Drer\nr3c1, Drer\esr2a, Drer\pparab, Drer\nr2f1a, Drer\vdra, Drer\ppardb, Drer\vdrb, Drer\nr1d2a, Drer\esr2b, Drer\rxrab, Drer\pgr, Drer\esrrd, Drer\nr1d2b, Drer\rxrga, Drer\pparg, Drer\pparaa, Drer\esrrga, Drer\nr6a1b, Drer\nr2f2, Drer\nr1h4, Drer\nr2c1, Drer\pparda, Drer\esrra, Drer\esr1, Drer\nr2f6a, Drer\nr2f1b, Drer\nr2c2, Drer\nr2e3, Drer\rargb, Drer\rxrbb, Drer\nr1d4a, Drer\nr0b2b, Drer\nr1h5, Drer\nr0b1, Drer\nr2e1, Drer\rarab, Drer\nr1d1, Drer\rxraa, Drer\raraa, Drer\nr1d4b, Drer\rxrba, Drer\nr0b2a" - "Cele\nhr-142, Cele\nhr-44, Cele\nhr-90, Cele\nhr-285, Cele\nhr-243, Cele\nhr-235, Cele\nhr-68, Cele\nhr-260, Cele\nhr-155, Cele\srt-58, Cele\nhr-287, Cele\nhr-106, Cele\nhr-241, Cele\nhr-283, Cele\nhr-192, Cele\Y47D7A.3, Cele\nhr-218, Cele\nhr-13, Cele\nhr-71, Cele\nhr-227, Cele\nhr-252, Cele\nhr-194, Cele\nhr-130, Cele\nhr-82, Cele\nhr-182, Cele\nhr-1, Cele\nhr-40, Cele\nhr-46, Cele\nhr-254, Cele\nhr-280, Cele\nhr-20, Cele\nhr-183, Cele\nhr-77, Cele\nhr-174, Cele\nhr-270, Cele\nhr-95, Cele\nhr-126, Cele\nhr-37, Cele\nhr-272, Cele\nhr-12, Cele\nhr-216, Cele\nhr-78, Cele\nhr-274, Cele\nhr-145, Cele\nhr-112, Cele\nhr-158, Cele\nhr-66, Cele\nhr-196, Cele\nhr-19, Cele\nhr-22, Cele\nhr-21, Cele\nhr-188, Cele\nhr-65, Cele\nhr-195, Cele\nhr-251, Cele\nhr-114, Cele\nhr-238, Cele\nhr-117, Cele\nhr-47, Cele\nhr-233, Cele\nhr-140, Cele\nhr-122, Cele\nhr-42, Cele\nhr-223, Cele\nhr-84, Cele\nhr-273, Cele\nhr-4, Cele\nhr-101, Cele\nhr-179, Cele\nhr-244, Cele\ZK418.11, Cele\nhr-33, Cele\nhr-9, Cele\nhr-203, Cele\nhr-257, Cele\nhr-94, Cele\nhr-107, Cele\nhr-76, Cele\nhr-7, Cele\nhr-193, Cele\nhr-184, Cele\nhr-115, Cele\nhr-198, Cele\nhr-189, Cele\nhr-275, Cele\nhr-212, Cele\nhr-164, Cele\sex-1, Cele\nhr-80, Cele\nhr-62, Cele\nhr-104, Cele\nhr-242, Cele\nhr-265, Cele\nhr-170, Cele\nhr-102, Cele\nhr-175, Cele\nhr-169, Cele\ZK1037.13, Cele\nhr-45, Cele\nhr-108, Cele\nhr-110, Cele\nhr-51, Cele\nhr-58, Cele\nhr-128, Cele\nhr-81, Cele\nhr-87, Cele\nhr-197, Cele\nhr-237, Cele\nhr-288, Cele\nhr-16, Cele\nhr-132, Cele\nhr-50, Cele\nhr-229, Cele\nhr-73, Cele\nhr-127, Cele\nhr-199, Cele\nhr-139, Cele\nhr-10, Cele\nhr-267, Cele\nhr-161, Cele\nhr-259, Cele\nhr-61, Cele\nhr-96, Cele\nhr-18, Cele\nhr-205, Cele\nhr-105, Cele\nhr-52, Cele\nhr-38, Cele\nhr-133, Cele\nhr-103, Cele\nhr-63, Cele\nhr-143, Cele\nhr-167, Cele\nhr-3, Cele\nhr-43, Cele\nhr-55, Cele\nhr-159, Cele\nhr-86, Cele\nhr-178, Cele\nhr-157, Cele\nhr-121, Cele\nhr-162, Cele\nhr-225, Cele\nhr-23, Cele\nhr-264, Cele\nhr-163, Cele\nhr-146, Cele\nhr-232, Cele\nhr-74, Cele\nhr-26, Cele\nhr-187, Cele\nhr-231, Cele\nhr-165, Cele\nhr-166, Cele\nhr-70, Cele\nhr-228, Cele\nhr-171, Cele\daf-12, Cele\nhr-11, Cele\nhr-282, Cele\nhr-98, Cele\nhr-156, Cele\nhr-226, Cele\nhr-281, Cele\nhr-201, Cele\nhr-99, Cele\nhr-15, Cele\nhr-39, Cele\nhr-271, Cele\nhr-138, Cele\nhr-53, Cele\nhr-185, Cele\nhr-190, Cele\nhr-222, Cele\nhr-211, Cele\nhr-2, Cele\nhr-210, Cele\nhr-172, Cele\nhr-125, Cele\nhr-54, Cele\nhr-131, Cele\nhr-253, Cele\nhr-268, Cele\nhr-217, Cele\nhr-219, Cele\nhr-269, Cele\nhr-135, Cele\nhr-230, Cele\nhr-113, Cele\nhr-72, Cele\nhr-32, Cele\nhr-150, Cele\nhr-79, Cele\nhr-247, Cele\nhr-213, Cele\nhr-123, Cele\nhr-256, Cele\nhr-261, Cele\nhr-181, Cele\nhr-6, Cele\nhr-59, Cele\nhr-262, Cele\nhr-57, Cele\nhr-56, Cele\unc-55, Cele\nhr-202, Cele\nhr-124, Cele\nhr-48, Cele\nhr-92, Cele\nhr-27, Cele\nhr-30, Cele\nhr-177, Cele\nhr-109, Cele\nhr-248, Cele\nhr-234, Cele\nhr-286, Cele\nhr-258, Cele\nhr-214, Cele\dpr-1, Cele\nhr-180, Cele\nhr-85, Cele\nhr-245, Cele\nhr-255, Cele\nhr-89, Cele\nhr-28, Cele\nhr-186, Cele\nhr-176, Cele\nhr-206, Cele\nhr-134" "Xtro\nr6a1, Xtro\esrrb, Xtro\nr3c2, Xtro\nr2f1, Xtro\ppara, Xtro\esr1, Xtro\nr2e3, Xtro\nr1i2, Xtro\rxrb, Xtro\pparg, Xtro\nr2f6, Xtro\nr1d1, Xtro\esrrgr, Xtro\pgr, Xtro\ar, Xtro\nr2c2, Xtro\nr2e1, Xtro\nr0b2, Xtro\esrrg, Xtro\nr2f2, Xtro\esr2, Xtro\nr1h5, Xtro\thrb, Xtro\rarg, Xtro\esrra, Xtro\nr1d2, Xtro\nr1h2, Xtro\nr2c1, Xtro\ppard, Xtro\rxra, Xtro\rxrg, Xtro\rara, Xtro\rarb, Xtro\vdr, Xtro\nr3c1, Xtro\nr2f5, Xtro\nr0b1" "Mmus\Nr2f6, Mmus\Nr0b2, Mmus\Esr1, Mmus\Nr6a1, Mmus\Ppard, Mmus\Esrrb, Mmus\Ar, Mmus\Nr1h4, Mmus\Esr2, Mmus\Rxrb, Mmus\Nr2f1, Mmus\Rarb, Mmus\Nr2c1, Mmus\Vdr, Mmus\Thrb, Mmus\Esrrg, Mmus\Nr2f2, Mmus\Nr2c2, Mmus\Thra, Mmus\Rxra, Mmus\Nr2e1, Mmus\Rara, Mmus\Rarg, Mmus\Pgr, Mmus\Nr2e3, Mmus\Esrra, Mmus\Nr1h5, Mmus\Ppara, Mmus\Nr1i2, Mmus\Nr1i3, Mmus\Nr1d1, Mmus\Nr1h3, Mmus\Nr0b1, Mmus\Pparg, Mmus\Rxrg, Mmus\Nr1h2, Mmus\Nr3c1, Mmus\Nr3c2, Mmus\Nr1d2" "Hsap\NR2C1, Hsap\ESRRG, Hsap\RARG, Hsap\RXRA, Hsap\RARB, Hsap\ESR2, Hsap\NR1H2, Hsap\AR, Hsap\PGR, Hsap\NR1I2, Hsap\NR2E1, Hsap\NR6A1, Hsap\PPARA, Hsap\NR3C2, Hsap\ESRRB, Hsap\NR2F1, Hsap\NR1D2, Hsap\NR2C2, Hsap\THRA, Hsap\RXRG, Hsap\ESR1, Hsap\NR1D1, Hsap\NR0B2, Hsap\NR1H3, Hsap\VDR, Hsap\NR3C1, Hsap\NR2F2, Hsap\NR1I3, Hsap\NR0B1, Hsap\ESRRA, Hsap\NR1H4, Hsap\RXRB, Hsap\RARA, Hsap\THRB, Hsap\PPARD, Hsap\PPARG, Hsap\NR2F6" larval stage | late third instar larval stage embryonic/larval salivary gland

"developmental rate defective,large body,lethal,lethal - all die during pupal stage,viable,fertile,visible,recessive,partially lethal - majority die,lethal - all die before end of second instar larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority live,flightless,uncoordinated,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,long lived,starvation stress response defective,male limited" "wing,egg,germline clone,follicle cell,oocyte,germline cell,female,embryonic/larval midgut,midgut constriction 1,midgut chamber 3,mouth hooks,embryonic/larval anterior spiracle,eye" FBgn0004583 ex expanded http://flybase.org/reports/FBgn0004583 "FBgn0000220, FBgn0000610, FBgn0002118, FBgn0010479, FBgn0021897" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Mer protein binding ; GO:0005515 | inferred from physical interaction with hpo protein binding ; GO:0005515 | inferred from physical interaction with yki "decapentaplegic signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp border follicle cell migration ; GO:0007298 | inferred from mutant phenotype regulation of organ growth ; GO:0046620 | inferred from genetic interaction with wts negative regulation of imaginal disc growth ; GO:0045571 | traceable author statement negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype inferred from genetic interaction with Mer negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype regulation of exit from mitosis ; GO:0007096 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay cell cycle arrest ; GO:0007050 | inferred from genetic interaction with Mer negative regulation of imaginal disc growth ; GO:0045571 | inferred from genetic interaction with wts negative regulation of organ growth ; GO:0046621 | inferred from genetic interaction with Mer ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype negative regulation of imaginal disc growth ; GO:0045571 | inferred from mutant phenotype regulation of cell differentiation ; GO:0045595 | inferred from genetic interaction with Mer hippo signaling ; GO:0035329 | inferred from genetic interaction with wts regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from genetic interaction with Mer positive regulation of phosphorylation ; GO:0042327 | inferred from genetic interaction with Mer regulation of signal transduction ; GO:0009966 | inferred from genetic interaction with Mer regulation of apoptotic process ; GO:0042981 | inferred from genetic interaction with Mer hippo signaling ; GO:0035329 | inferred from genetic interaction with hpo compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with crb negative regulation of organ growth ; GO:0046621 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype regulation of growth ; GO:0040008 | inferred from genetic interaction with RpL36 regulation of growth ; GO:0040008 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype negative regulation of hippo signaling ; GO:0035331 | inferred from genetic interaction with wts inferred from physical interaction with yki compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from genetic interaction with Mer endocytic recycling ; GO:0032456 | inferred from genetic interaction with Mer" cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 apical plasma membrane ; GO:0016324 | inferred from direct assay apical plasma membrane ; GO:0016324 | traceable author statement Kibra-Ex-Mer complex ; GO:0036375 | inferred from direct assay zonula adherens ; GO:0005915 | traceable author statement "ex, CG4114, l(2)01270, 1270, l(2)ey, Ex, brl, Expanded, expanded" "IPR000299:FERM domain, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR018980:FERM, C-terminal PH-like domain, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain" CG4114 11-Aug-17 DroID_v2017_08 "Drer\frmd6, Drer\zgc:172136" - Cele\frm-7 - Mmus\Frmd6 "Hsap\FRMD6, Hsap\FRMD1" larval stage imaginal disc

larval stage " dorsal mesothoracic disc

, imaginal disc

, ventral thoracic disc

" "lethal,recessive,visible,somatic clone,mitotic cell cycle defective,viable,increased cell number,cell non-autonomous,fertile,hyperplasia,cell migration defective,decreased cell size,partially lethal - majority die,planar polarity defective,cold sensitive,uncoordinated,decreased cell number,lethal - all die before end of P-stage,some die during pharate adult stage,increased cell death,size defective" "eye,somatic clone,interommatidial bristle,supernumerary,ommatidium,cell autonomous,cell non-autonomous,retina,eye disc,eye-antennal disc,wing disc,photoreceptor cell,spermatogonial cyst,vibrissae,anterior scutellar bristle,wing,pigment cell,border follicle cell,leg,thorax,anterior crossvein,posterior crossvein,interommatidial bristle & eye disc & pupa,imaginal disc,wing vein,adult thorax,adult abdomen,antenna,postgenal sensillum,cold sensitive,adult head,embryonic/larval optic lobe,antennal sense organ,head,prothoracic tarsal segment 3,prothoracic tarsal segment 4,prothoracic tarsal segment 5,mesothoracic tarsal segment 3,mesothoracic tarsal segment 4,mesothoracic tarsal segment 5,metathoracic tarsal segment 3,metathoracic tarsal segment 4,metathoracic tarsal segment 5,arista,haltere disc,prothoracic leg disc,mesothoracic leg disc,metathoracic leg disc,embryonic/larval glial cell,ectopic,wing margin,anterior,eye photoreceptor cell,cone cell,inter-ommatidial cell | pupal stage,eye disc | third instar larval stage,morphogenetic furrow | third instar larval stage,1st posterior cell,mesothoracic tergum,inter-ommatidial cell,posterior" FBgn0069228 gl(2L)37-36 gl(2L)37-36 http://flybase.org/reports/FBgn0069228 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)37-36 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0011746 ana anachronism http://flybase.org/reports/FBgn0011746 - protein_coding_gene - - - "ana, med, CG8084" - CG8084 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage , embryonic stage | stage >13 " " optic lobe

, larval central nervous system | restricted

, glial cell

, larval brain

, embryonic central nervous system | restricted

, ventral nerve cord

" " embryonic stage | stage >13 , larval stage " " embryonic central nervous system | restricted

, larval central nervous system | restricted

, optic lobe

, larval brain

, ventral nerve cord

, glial cell

" "viable,smell perception defective,recessive,wild-type" "type I neuroblast,somatic clone,neuroblast,thoracic neuroblast,optic lobe & neuroblast" DRSC07579 E 0.886816569 -0.305318874 1.442945115 -1.723643439 0.76349373 0.1621361 FBgn0011655 Med Medea http://flybase.org/reports/FBgn0011655 "FBgn0002479, FBgn0002509, FBgn0013946, FBgn0027760" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR013019 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transforming growth factor beta receptor, common-partner cytoplasmic mediator activity ; GO:0030616 | non-traceable author statement DNA binding ; GO:0003677 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Mad protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NB71" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001132, InterPro:IPR003619, InterPro:IPR013019, InterPro:IPR013790 negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement heart development ; GO:0007507 | traceable author statement germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | traceable author statement imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from sequence or structural similarity with HGNC:6770 inferred from mutant phenotype inferred from genetic interaction with dpp inferred from genetic interaction with tkv inferred from genetic interaction with zen neuron development ; GO:0048666 | inferred from mutant phenotype BMP signaling pathway ; GO:0030509 | traceable author statement transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from genetic interaction with dpp dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype" transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR013019 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from physical interaction with Mad "med, medea, dSmad4, l(3)SG70, l(3)12m-137, l(3)11m-254, l(3)XIIm137, l(3)SG36, anon-EST:Posey121, E(zen)3, CG1775, Med, SMAD4, MED, Smad4, smad4, Medea" "IPR001132:SMAD domain, Dwarfin-type, IPR003619:MAD homology 1, Dwarfin-type, IPR008984:SMAD/FHA domain, IPR013019:MAD homology, MH1, IPR013790:Dwarfin, IPR017855:SMAD domain-like, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG1775 11-Aug-17 DroID_v2017_08 "Drer\smad6a, Drer\smad9, Drer\smad7, Drer\smad3b, Drer\gb:cr929477, Drer\smad3a, Drer\smad5, Drer\smad6b, Drer\smad4a, Drer\si:dkey-239n17.4, Drer\smad2, Drer\si:dkey-222b8.1" - "Cele\daf-3, Cele\sma-4" "Xtro\smad1, Xtro\smad9, Xtro\smad6, Xtro\smad2, Xtro\smad4.2, Xtro\smad7, Xtro\smad6.2, Xtro\smad4.1, Xtro\smad3" "Mmus\Smad7, Mmus\Smad9, Mmus\Smad4, Mmus\Smad1, Mmus\Smad3, Mmus\Smad6, Mmus\Smad2, Mmus\Smad5" "Hsap\SMAD4, Hsap\SMAD6, Hsap\SMAD3, Hsap\SMAD5, Hsap\SMAD7, Hsap\SMAD2, Hsap\SMAD1, Hsap\SMAD9" " embryonic stage | stage 16 , embryonic stage | stage 14 , embryonic stage | stage 7 , embryonic stage | stage 4 , embryonic stage | >=stage 14 " " midgut constriction 2

, ectoderm

, mesoderm

,

anterior , endoderm

, embryonic central nervous system | restricted

" "visible,neuroanatomy defective,neurophysiology defective,small body,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,wild-type,cell growth defective,somatic clone,viable,lethal - all die before end of embryonic stage,germline clone,rescuable maternal effect,some die during embryonic stage,maternal effect" "wing vein,ectopic,wing,leg,bouton,neuromuscular junction,neuromuscular junctionKpn-A),embryonic/larval somatic muscle,embryonic/larval central nervous system,imaginal disc,cell cycle,embryonic/first instar larval cuticle,denticle belt,larval head,eye,somatic clone,amnioserosa,lamina,eye photoreceptor cell stalk,gastric caecum,embryonic/larval midgut,midgut constriction 2,female germline stem cell,germarium,male germline stem cell,germline clone,follicle stem cell,follicle cell,crystal cell,synapse,t-bar,filzkorper,dorso-lateral,posterior crossvein,wing vein L4,dorsal cluster neuron,chorion | maternal effect | somatic clone,egg operculum,maternal effect,eye disc,fat body,wing disc,adult thorax,tibia,femur,tarsal segment 4,embryonic epidermis,pretarsus,ventral,cell non-autonomous,wing hinge,cell autonomous,wing margin,morphogenetic furrow" FBgn0000585 erratic erratic http://flybase.org/reports/FBgn0000585 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)31El, erratic, err" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect" FBgn0262404 mir-996 mir-996 stem loop http://flybase.org/reports/FBgn0262404 miRNA_gene - - - "mir-996, miR-996, 996, dme-mir-996, CR42947, miR996, dme-miR-996" - CR42947 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030711 Rrp47 Ribosomal RNA processing 47 http://flybase.org/reports/FBgn0030711 protein_coding_gene - regulation of gene expression ; GO:0010468 | inferred from mutant phenotype exosome (RNase complex) ; GO:0000178 | colocalizes_with inferred from direct assay "CG8928, Rrp47, dRrp47, lincRNA.1007" "IPR007146:Sas10/Utp3/C1D, IPR011082:Exosome-associated factor Rrp47/DNA strand repair C1D" CG8928 11-Aug-17 DroID_v2017_08 Drer\c1d Scer\LRP1 Cele\Y51H7C.7 Xtro\c1d Mmus\C1d Hsap\C1D "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000543 ecd ecdysoneless http://flybase.org/reports/FBgn0000543 FBgn0035324 protein_coding_gene snRNP binding ; GO:0070990 | inferred from physical interaction with Prp8 inferred from physical interaction with CG12320 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000316625 "lymph gland development ; GO:0048542 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype response to symbiont ; GO:0009608 | inferred from mutant phenotype inferred from genetic interaction with hop mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:1903220 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000316625 mushroom body development ; GO:0016319 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | traceable author statement instar larval or pupal development ; GO:0002165 | traceable author statement chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype progression of morphogenetic furrow involved in compound eye morphogenesis ; GO:0007458 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000316625 cytoplasm ; GO:0005737 | inferred from direct assay "ecd, CG5714, ecd1, l(3)ecd, l(3)ecd1, ecdl, ecd-1, l(3)ecd-1, l(3)62Db" IPR010770:Ecd family CG5714 11-Aug-17 DroID_v2017_08 Drer\ecd - Cele\F19C6.2 Xtro\ecd Mmus\Ecd Hsap\ECD unfertilized egg stage egg

"increased cell death,visible,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,small body,immune response defective,heat sensitive,recessive,short lived,lethal,female sterile,temperature conditional,neuroanatomy defective,developmental rate defective,locomotor behavior defective,neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,germline clone,dominant,partially,maternal effect,viable" "wing disc,anterior crossvein,1st posterior cell,prothoracic gland,macrochaeta & adult thorax,embryonic/larval lymph gland,eye,heat sensitive,morphogenetic furrow,egg chamber,nurse cell,follicle cell,yolk,egg,blastoderm embryo,stomodeal invagination,amnioproctodeal invagination,extended germ band embryo,lamellocyte,hemocyte,eye-antennal disc,ventral thoracic disc,macrochaeta & adult thorax | conditional ts,larva,vitelline membrane,chorion,Golgi stack | heat sensitive,dorsal closure embryo,embryonic/first instar larval cuticle,border follicle cell,synapse | heat sensitive,NMJ bouton,embryonic/larval neuromuscular junction,embryonic/larval Malpighian tubule Type II cell,female germline cell,supernumerary,fusome | heat sensitive,lobe system of adult mushroom body,mushroom body beta-lobe,mouth hooks,germline clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0024836 stan starry night http://flybase.org/reports/FBgn0024836 FBgn0026246 protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000832, InterPro:IPR001879 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR002126, InterPro:IPR015919 signal transducer activity, downstream of receptor ; GO:0005057 | inferred from sequence model receptor activity ; GO:0004872 | inferred from sequence or structural similarity transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity signal transducer activity, downstream of receptor ; GO:0005057 | inferred from mutant phenotype cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity" "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000832 homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity ommatidial rotation ; GO:0016318 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | traceable author statement Wnt signaling pathway ; GO:0016055 | inferred from expression pattern establishment of planar polarity ; GO:0001736 | traceable author statement regulation of synapse assembly ; GO:0051963 | inferred from direct assay homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay dendrite self-avoidance ; GO:0070593 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from sequence or structural similarity segment polarity determination ; GO:0007367 | inferred from expression pattern morphogenesis of a polarized epithelium ; GO:0001738 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from sequence or structural similarity positive regulation of Wnt signaling pathway ; GO:0030177 | non-traceable author statement establishment of tissue polarity ; GO:0007164 | non-traceable author statement negative regulation of Wnt signaling pathway ; GO:0030178 | traceable author statement positive regulation of axon extension ; GO:0045773 | inferred from genetic interaction with DAAM mushroom body development ; GO:0016319 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | non-traceable author statement regulation of establishment of planar polarity ; GO:0090175 | inferred from genetic interaction with dgo positive regulation of axon guidance ; GO:1902669 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype dendrite development ; GO:0016358 | inferred from expression pattern regulation of axonogenesis ; GO:0050770 | inferred from direct assay establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype R3/R4 development ; GO:0048057 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR020894 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000832 cell-cell junction ; GO:0005911 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "Fmi, fmi, Stan, Flam, CT20776, fmi/stan, CG11895, stan, STAN" "IPR017981:GPCR, family 2-like, IPR015919:Cadherin-like, IPR000203:GPS motif, IPR000742:EGF-like domain, IPR000832:GPCR, family 2, secretin-like, IPR001791:Laminin G domain, IPR001879:GPCR, family 2, extracellular hormone receptor domain, IPR001881:EGF-like calcium-binding domain, IPR002049:Laminin EGF domain, IPR002126:Cadherin, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR020894:Cadherin conserved site, IPR032471:GAIN domain, N-terminal" CG11895 11-Aug-17 DroID_v2017_08 "Drer\celsr3, Drer\celsr1a, Drer\celsr1b, Drer\celsr2" - Cele\fmi-1 "Xtro\celsr1, Xtro\celsr3, Xtro\celsr2" "Mmus\Celsr3, Mmus\Celsr2, Mmus\Celsr1" "Hsap\CELSR3, Hsap\CELSR2, Hsap\CELSR1" " embryonic stage--pupal stage , pupal stage " wing

" larval stage | third instar , pupal stage | early , pupal stage " " lamina & neuron

restricted , photoreceptor cell

, ovarian sheath cell

, medulla && neuron

" "partially lethal - majority die,neuroanatomy defective,planar polarity defective,viable,fertile,decreased cell number,somatic clone,recessive,cell autonomous,lethal,cell non-autonomous,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,cell polarity defective,body size defective,developmental rate defective,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,dominant" "dorsal multidendritic neuron ddaC,dendrite | third instar larval stage,photoreceptor cell R8,somatic clone,class IV dendritic arborizing neuron,wing hair,ommatidium,embryonic/larval mushroom body,adult mushroom body,calyx of adult mushroom body,photoreceptor cell R4,cell non-autonomous,dendrite | dorsal | embryonic stage,dorsal multidendritic neuron,dorsal multidendritic neuron ddaE,multidendritic neuron,neuromuscular junction | ectopic,wing,thorax,leg,adult thorax,precursor,wing cell,trichome & abdominal tergite,cell autonomous,embryonic/larval dorsal trunk,embryonic/larval neuron,dorsal wing blade,eye photoreceptor cell,longitudinal connective,2nd posterior cell & wing hair,macrochaeta,microchaeta & scutum,dorsocentral bristle,presumptive embryonic/larval peripheral nervous system,photoreceptor cell & axon,photoreceptor cell R8 & axon,photoreceptor cell R8 & axon & growth cone,photoreceptor cell R3,dendritic arborizing neuron,axon & photoreceptor cell R8 | somatic clone,trichome & pleural membrane | somatic clone,neuromuscular junction | ectopicstan2),neuromuscular junctionstan2),intersegmental nerve,microchaeta,trichome & adult abdomenptc-559.1,wing hair & 1st posterior cellptc-559.1,ectopic,sensory mother cell & spindleap-md52,vertical lobe of adult mushroom body,axon & photoreceptor cell R8 | somatic clone, standsRNA.extra.UAS,axon & photoreceptor cell R8 | somatic clone, standsRNA.intra.UAS,supernumerary" FBgn0004795 retn retained http://flybase.org/reports/FBgn0004795 "FBgn0010517, FBgn0014151, FBgn0063144" protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001228 | inferred from biological aspect of ancestor with PANTHER:PTN000394188 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with gro RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000394188" "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | non-traceable author statement anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype gliogenesis ; GO:0042063 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype salivary gland development ; GO:0007431 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "dri, Dead Ringer/Retain, Dri, DRI, retn/dri, EY2-10, l(2)02535, 2535, CG5403, BcDNA:LD35748, retn, Retn, EHMT" "IPR001606:ARID DNA-binding domain, IPR023334:REKLES domain, IPR011989:Armadillo-like helical" CG5403 11-Aug-17 DroID_v2017_08 "Drer\arid3a, Drer\arid3c, Drer\arid5b, Drer\arid4b, Drer\arid3b, Drer\arid4a, Drer\si:dkey-205h23.1" "Scer\RSC9, Scer\ECM5, Scer\SWI1" "Cele\cfi-1, Cele\let-526, Cele\arid-1" "Xtro\arid3b, Xtro\arid4a, Xtro\arid3a, Xtro\arid4b" "Mmus\Arid5a, Mmus\Arid3c, Mmus\Arid3a, Mmus\Arid5b, Mmus\Arid4b, Mmus\Arid3b, Mmus\Arid2, Mmus\Arid4a" "Hsap\ARID5A, Hsap\ARID3C, Hsap\ARID3A, Hsap\ARID3B, Hsap\ARID5B, Hsap\ARID4A, Hsap\ARID4B, Hsap\ARID2" " embryonic stage | stage 15,16 , embryonic stage | stage 5-7 , embryonic stage | <2hr , embryonic stage | 3-5 hr , embryonic stage | 2-3hr " " anterior embryonic/larval midgut

, organism | 0-30% egg length

,

ubiquitous , labral segment

, pharyngeal muscle

, posterior embryonic/larval midgut

, organism | 70-100% egg length

, mesoderm

, embryonic/larval hindgut

,

40-60% egg length , embryonic/larval salivary gland duct

" " embryonic stage | 2-3hr , embryonic stage | stage 15,16 , embryonic stage , embryonic stage | 3-5 hr , embryonic stage | <2hr " "

0-25% egg length , amnioserosa

, embryonic salivary gland

,

75-100% egg length , mesoderm

, embryonic/larval foregut

, embryonic ventral nervous system | segmentally repeated

,

40-60% egg length ,

ubiquitous , ring gland

, embryonic brain | restricted

" "neuroanatomy defective,somatic clone,lethal,partially,courtship behavior defective,female,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,visible,female sterile,fertile,reduced,behavior defective,rescuable maternal effect,mitotic cell cycle defective,germline clone" "embryonic/larval somatic muscle,egg,germline clone,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,mushroom body beta-lobe,adult mushroom body,subesophageal ganglion,somatic clone,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,embryonic/larval hindgut,wing vein,sensillum campaniformium,wing sensillum,neuron,longitudinal connective,interface glial cell,syncytial blastoderm embryo,embryonic segment,extended germ band embryo,cephalopharyngeal skeleton,hypostomal sclerite,lateral process,somatic muscle,pharyngeal muscle,embryonic/larval pericardial cell,dorsal closure embryo,embryonic hindgut,embryonic/larval glial cell,axonMZ1580" FBgn0026623 ripp rippchen http://flybase.org/reports/FBgn0026623 - gene molecular_function ; GO:0003674 | no biological data available central nervous system development ; GO:0007417 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "rip, ripp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic/larval central nervous system,commissure,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,dorsal closure embryo,embryonic ventral epidermis,ventral nerve cord,embryonic/larval midgut,embryonic/larval foregut,embryonic/larval hindgut,glial cell,midline glial cell,ectopic" FBgn0026091 E(lt[v])335 E(lt[v])335 http://flybase.org/reports/FBgn0026091 - gene - - - E(lt[v])335 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003170 pvt postverticalless http://flybase.org/reports/FBgn0003170 - gene - - - pvt - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male fertile,viable,female sterile" "wing,adult thorax & microchaeta,postvertical bristle,adult head,eye" FBgn0031604 Elp3 Elongator complex protein 3 http://flybase.org/reports/FBgn0031604 protein_coding_gene "iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR006638, InterPro:IPR007197 N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 phosphorylase kinase regulator activity ; GO:0008607 | inferred from sequence or structural similarity with UniProtKB:Q9H9T3 acetyltransferase activity ; GO:0016407 | inferred from direct assay" cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype regulation of photoreceptor cell axon guidance ; GO:2000289 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:Q9H9T3 peptidyl-lysine acetylation ; GO:0018394 | inferred from direct assay instar larval development ; GO:0002168 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype hemopoiesis ; GO:0030097 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9H9T3 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:20696 cytoplasm ; GO:0005737 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from sequence or structural similarity with UniProtKB:Q9H9T3 "ELP3, elp3, dmHAG408, Dmel/ELP3, HAT, Elp3, Dmel\ELP3, CG15433, elp-3, D-elp3" "IPR000182:GNAT domain, IPR005910:Histone acetyltransferase ELP3, IPR006638:Elongator protein 3/MiaB/NifB, IPR007197:Radical SAM, IPR016181:Acyl-CoA N-acyltransferase, IPR013785:Aldolase-type TIM barrel, IPR032432:Radical SAM, C-terminal extension" CG15433 11-Aug-17 DroID_v2017_08 Drer\elp3 Scer\ELP3 Cele\elpc-3 Xtro\elp3 Mmus\Elp3 Hsap\ELP3 "lethal,neurophysiology defective,neuroanatomy defective,viable,visible,heat sensitive,hyperactive,partially lethal - majority die,some die during pupal stage,sleep defective" "presynaptic cytoskeletal matrix assembled at active zones,photoreceptor cell,trichogen cell,NMJ bouton,type I bouton" FBgn0015245 Hsp60A Heat shock protein 60A http://flybase.org/reports/FBgn0015245 "FBgn0001483, FBgn0001749, FBgn0004659, FBgn0010375" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002423, InterPro:IPR018370 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P10809" protein refolding ; GO:0042026 | inferred from electronic annotation with InterPro:IPR001844 cellular response to heat ; GO:0034605 | inferred from expression pattern apoptotic mitochondrial changes ; GO:0008637 | inferred from biological aspect of ancestor with PANTHER:PTN000143510 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype protein import into mitochondrial intermembrane space ; GO:0045041 | inferred from biological aspect of ancestor with PANTHER:PTN000143508 'de novo' protein folding ; GO:0006458 | inferred from sequence or structural similarity with UniProtKB:P10809 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 response to heat ; GO:0009408 | NOT inferred from expression pattern chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:P10809 sleep ; GO:0030431 | inferred from expression pattern mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000143507 lipid particle ; GO:0005811 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P10809 microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from direct assay "hsp60, Hsp60, CG12101, Hsp60A, HSP60, Dmhsp60, l(1)BP5, Cpn60, BP5, 12, G62, l(1)dp025, l(1)L12, l(1)HM21, l(1)G8, l(1)10Ac, Mmp-P1, Hsp 60, cpn60, d-hsp60, hsp60A, IEF16, SSP 7506, HSP60A, DmHsp60, Hsp64, Dm10A" "IPR018370:Chaperonin Cpn60, conserved site, IPR001844:Chaperonin Cpn60, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG12101 11-Aug-17 DroID_v2017_08 Drer\hspd1 "Scer\HSP60, Scer\TCM62" Cele\hsp-60 Xtro\hspd1 Mmus\Hspd1 Hsap\HSPD1 "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,wild-type,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,polyphasic,cell lethal,germline clone,cold sensitive" "tergite,blastoderm embryo" FBgn0050359 Mal-A5 Maltase A5 http://flybase.org/reports/FBgn0050359 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "CG8689, CG30359, Mal-A5, mal_A5, Drome_A5" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG30359 11-Aug-17 DroID_v2017_08 "Drer\slc3a2b, Drer\zgc:158423, Drer\slc3a1, Drer\si:dkey-202g17.3, Drer\slc3a2a" "Scer\MAL12, Scer\IMA4, Scer\MAL32, Scer\IMA2, Scer\IMA1, Scer\IMA3, Scer\IMA5" "Cele\atgp-1, Cele\atgp-2" "Xtro\slc3a1, Xtro\slc3a2" "Mmus\Slc3a1, Mmus\Slc3a2" "Hsap\SLC3A1, Hsap\SLC3A2" viable FBgn0016031 lama lamina ancestor http://flybase.org/reports/FBgn0016031 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc development ; GO:0007444 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay "CG10645, lama" IPR007000:Phospholipase B-like CG10645 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-139e5.2, Drer\plbd1, Drer\zgc:158619" - "Cele\Y37D8A.2, Cele\F09B12.3, Cele\Y54F10AM.8" Xtro\plbd2 "Mmus\Plbd1, Mmus\Plbd2" "Hsap\PLBD1, Hsap\PLBD2" "behavior defective,recessive,learning defective,viable,fertile" "germline cell,male,dorsal appendage" DRSC11361 K 0.233100554 0.391387124 0.451408271 0.574265529 -1.841436218 0.602202598 FBgn0001417 l(1)6Da lethal (1) 6Da http://flybase.org/reports/FBgn0001417 - gene - - - l(1)6Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" female reproductive system FBgn0023440 grape Grape http://flybase.org/reports/FBgn0023440 - gene - - - "gra, grape" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible FBgn0060769 l(3)S062118b lethal (3) S062118b http://flybase.org/reports/FBgn0060769 gene - - - "0621/18, l(3)S062118b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0010399 Nmdar1 NMDA receptor 1 http://flybase.org/reports/FBgn0010399 - protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 NMDA glutamate receptor activity ; GO:0004972 | inferred from sequence or structural similarity NMDA glutamate receptor activity ; GO:0004972 | contributes_to inferred from direct assay ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 long-term memory ; GO:0007616 | inferred from mutant phenotype calcium ion homeostasis ; GO:0055074 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from genetic interaction with Nmdar2 regulation of membrane potential ; GO:0042391 | inferred from mutant phenotype ionotropic glutamate receptor signaling pathway ; GO:0035235 | inferred from direct assay behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype sensory perception of touch ; GO:0050975 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from direct assay medium-term memory ; GO:0072375 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from genetic interaction with PQBP1 integral component of membrane ; GO:0016021 | inferred from direct assay postsynaptic membrane ; GO:0045211 | inferred from direct assay NMDA selective glutamate receptor complex ; GO:0017146 | inferred from direct assay ionotropic glutamate receptor complex ; GO:0008328 | inferred from physical interaction with Nmdar2 "dNR1, DrNR1, CG2902, dnmdar-I, NRI, nmr, DMNMDAR1, DNMDAR-I, Nmdar, DNmdar, Nmdar1, NMDAR1, NMdar1, NMDA R1, NMDA, NR1, DmelNmdar1, dsNR1, NMDAR, nr1, NmdaR1" "IPR018882:Calmodulin-binding domain C0, NMDA receptor, NR1 subunit, IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG2902 11-Aug-17 DroID_v2017_08 "Drer\grin2bb, Drer\grin3ba, Drer\grin3a, Drer\grin1b, Drer\grin2ab, Drer\grin2cb, Drer\LOC100149482, Drer\grin1a, Drer\LOC100329743, Drer\grin2aa, Drer\grin2da" - "Cele\nmr-1, Cele\glr-6" "Xtro\grin3b, Xtro\grin2d, Xtro\grin1, Xtro\grin2c, Xtro\grin2b" "Mmus\Grin1, Mmus\Grin2c, Mmus\Grin2a, Mmus\Grin3b, Mmus\Grin3a, Mmus\Grin2d, Mmus\Grin2b" "Hsap\GRIN2D, Hsap\GRIN3A, Hsap\GRIN1, Hsap\GRIN2C, Hsap\GRIN3B, Hsap\GRIN2B, Hsap\GRIN2A" "memory defective,heat sensitive,RU486 conditional,viable,recessive,learning defective,partially lethal - majority die,mating defective,dominant,phototaxis defective,neuroanatomy defective,touch sensitivity defective" "dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0261725 EC282 - http://flybase.org/reports/FBgn0261725 gene - - - EC282 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0000009 Abnormal-abdomen Abnormal abdomen http://flybase.org/reports/FBgn0000009 - gene - - - "Abnormal, Abnormal-abdomen, A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,semidominant,viable,female,female fertile" "tergite,cuticle,microchaeta & abdomen,macrochaeta & abdomen,sternite" FBgn0001064 Fs(3)Ros Female sterile (3) Rosd http://flybase.org/reports/FBgn0001064 - gene - - - "Fs(3)Rosd, Fs(3)Sz30, Fs(3)Ros" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic head,maternal effect" FBgn0259572 B0016 - http://flybase.org/reports/FBgn0259572 gene - - - B0016 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0067756 l(1)G0073 lethal (1) G0073 http://flybase.org/reports/FBgn0067756 gene - - - l(1)G0073 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0004680 fb fine bristle http://flybase.org/reports/FBgn0004680 - gene - - - fb - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,fertile,recessive" "macrochaeta,wing" FBgn0001801 l(1)Mc23 lethal (1) Mc23 http://flybase.org/reports/FBgn0001801 - gene - - - l(1)Mc23 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031629 Clect27 C-type lectin 27kD http://flybase.org/reports/FBgn0031629 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - "Clect27, CG3244" "IPR001304:C-type lectin-like, IPR018378:C-type lectin, conserved site, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG3244 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-225k7.3, Drer\si:dkey-28d5.8, Drer\si:ch211-282j17.7, Drer\si:dkey-28d5.14, Drer\si:dkey-88n24.10, Drer\si:ch211-225k7.2, Drer\si:ch211-63p21.4, Drer\si:dkey-28d5.12, Drer\si:dkey-28d5.10, Drer\si:dkey-83f18.7, Drer\si:ch211-282j17.11, Drer\si:ch211-282j17.8, Drer\si:dkey-28d5.15, Drer\si:dkey-28d5.4, Drer\si:dkey-83f18.10" - - - Mmus\Sell Hsap\SELL "visible,lethal,viable,fertile" "wing,anterior crossvein" FBgn0066324 toi toi http://flybase.org/reports/FBgn0066324 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype visual learning ; GO:0008542 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "toi, Toi" - - 11-Aug-17 DroID_v2017_08 - - - - - - "memory defective,visual behavior defective,recessive,learning defective,neurophysiology defective" FBgn0028577 hfp half pint http://flybase.org/reports/FBgn0028577 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with glo mRNA binding ; GO:0003729 | inferred from sequence or structural similarity poly(U) RNA binding ; GO:0008266 | inferred from sequence or structural similarity with protein_id:AAF05605 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype regulation of cell growth ; GO:0001558 | inferred from mutant phenotype mRNA splice site selection ; GO:0006376 | inferred from mutant phenotype alternative mRNA splicing, via spliceosome ; GO:0000380 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype cystoblast division ; GO:0007282 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with protein_id:AAF05605 negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype" protein complex ; GO:0043234 | inferred from physical interaction with glo nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "hfp, PUF60, DPUF68, HFP, pUbsf, dFIR, Puf60, CG12085, Hfp, Fir, anon-WO0118547.408, pUF68, puf68, PUF68, pUf68, Puf68" "IPR000504:RNA recognition motif domain, IPR006532:Poly-U binding splicing factor, half-pint, IPR034212:PUF60, RNA recognition motif 3, IPR034211:PUF60, RNA recognition motif 2, IPR034209:PUF60, RNA recognition motif 1, IPR003954:RNA recognition motif domain, eukaryote" CG12085 11-Aug-17 DroID_v2017_08 "Drer\puf60b, Drer\puf60a" Scer\PAB1 "Cele\ZK616.1, Cele\rad-26, Cele\rnp-6" Xtro\puf60 "Mmus\Sin3b, Mmus\Puf60" Hsap\PUF60 " embryonic stage | stage 1-4 , embryonic stage | stage 4-6 , adult stage | female " " organism

, ovary

" oogenesis stage ovary

"viable,developmental rate defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,large body,increased cell death,mitotic cell cycle defective,cytokinesis defective,lethal - all die before end of P-stage,some die during pharate adult stage,somatic clone,increased cell growth,male sterile,female sterile,fertile,neuroanatomy defective,visible,partially lethal - majority die" "melanotic mass,leg,wing,sex comb,scutellar bristle,wing disc,eye disc,mitosis & nuclear chromosome[-],actomyosin contractile ring[-],somatic clone | third instar larval stage,egg chamber,karyosome,nurse cell & nuclear chromosome,dorsal appendage,egg,nurse cell,ring canal,ovary,germline clone,eye,ommatidium,eye disc | larval stage,wing vein,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC08731 EK -0.373983275 0.419950369 -1.802455968 0.71895447 2.597959698 1.819433007 FBgn0032704 Jwa Jwa http://flybase.org/reports/FBgn0032704 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to ethanol ; GO:0045471 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay "CG10373, Jwa, djwa, GH05842p" IPR004895:Prenylated rab acceptor PRA1 CG10373 11-Aug-17 DroID_v2017_08 "Drer\praf2, Drer\arl6ip5a, Drer\arl6ip5b" - Cele\praf-3 Xtro\arl6ip5 "Mmus\Praf2, Mmus\Arl6ip5" "Hsap\ARL6IP5, Hsap\PRAF2" "chemical resistant,chemical sensitive,partially lethal - majority die,chemical conditional,viable" FBgn0015270 Orc2 Origin recognition complex subunit 2 http://flybase.org/reports/FBgn0015270 "FBgn0001009, FBgn0002365" protein_coding_gene DNA replication origin binding ; GO:0003688 | inferred from biological aspect of ancestor with PANTHER:PTN000362151 chromatin binding ; GO:0003682 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from direct assay eggshell chorion gene amplification ; GO:0007307 | traceable author statement DNA-dependent DNA replication ; GO:0006261 | inferred from sequence or structural similarity with SGD:S000000264 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype DNA replication ; GO:0006260 | traceable author statement nuclear origin of replication recognition complex ; GO:0005664 | inferred from sequence or structural similarity with SGD:S000000264 alpha-heterochromatin ; GO:0005723 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay "ORC2, k43, orc2, rDmORC, DmORC2, ORC, DmORC 2, l(3)88Ab, l(3)k43, Orc2p, l(3)K43, fs(3)293, l(3)dsl5, l(3)SG44, l(3)A5, fs(3)293-19, CG3041, Orc2, DmOrc2p, Orc-2, DmOrc2, dOrc2" "IPR007220:Origin recognition complex, subunit 2" CG3041 11-Aug-17 DroID_v2017_08 Drer\orc2 Scer\ORC2 Cele\orc-2 Xtro\orc2 Mmus\Orc2 Hsap\ORC2 embryonic stage && larval stage embryonic stage | 0-4hr "lethal,wild-type,lethal - all die before end of pupal stage,recessive,some die during pupal stage,suppressor of variegation,dominant,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,viable,female sterile,cold sensitive,neuroanatomy defective,visible" "polytene chromosome | larval stage,mitotic metaphase,mitosis & nuclear chromosome,nuclear chromosome,imaginal disc,mitotic cell cycle,chromosome, centromeric region,nuclear chromosome | larval stage,chromatin | larval stage,follicle cell,spindle,cell cycle,mitotic metaphase293‘_7),mitosis & nuclear chromosome293‘_7),chorion,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,wing" FBgn0004622 TkR99D Tachykinin-like receptor at 99D http://flybase.org/reports/FBgn0004622 "FBgn0011021, FBgn0044356, FBgn0044366" protein_coding_gene tachykinin receptor activity ; GO:0004995 | inferred from physical interaction with Tk tachykinin receptor activity ; GO:0004995 | inferred from direct assay tachykinin receptor activity ; GO:0004995 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model tachykinin receptor signaling pathway ; GO:0007217 | inferred from sequence or structural similarity negative regulation of synaptic transmission ; GO:0050805 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model olfactory behavior ; GO:0042048 | inferred from mutant phenotype positive regulation of sensory perception of pain ; GO:1904058 | inferred from mutant phenotype tachykinin receptor signaling pathway ; GO:0007217 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with RGDID:3810 inferred from sequence or structural similarity with RGDID:3811 "Takr99D, CG7887, TKR99D, TAKR99D, l(3)s2222, DTKR, Tak-r, anon-WO0131005.9, anon-WO0131005.11, Dtkr, dtkr, TLR2_DROME, TkR99D, DmTRPR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001681:Neurokinin receptor, IPR017452:GPCR, rhodopsin-like, 7TM" CG7887 11-Aug-17 DroID_v2017_08 "Drer\tacr1a, Drer\tacr2, Drer\tacr3l, Drer\tacr1b, Drer\tacr3a, Drer\LOC100333270" - "Cele\srv-34, Cele\npr-22, Cele\tkr-1, Cele\tkr-2" "Xtro\tacr1, Xtro\tacr3" "Mmus\Tacr3, Mmus\Tacr2, Mmus\Tacr1" "Hsap\TACR1, Hsap\TACR3, Hsap\TACR2" " embryonic stage--pupal stage , adult stage , embryonic stage | stage >=14 " " subesophageal ganglion

, adult brain cortex

, embryonic neuron

, adult head

, neuron &&of adult nervous system

, central nervous system

, embryonic brain

, embryonic ventral nervous system | restricted

" "smell perception defective,neurophysiology defective,viable,fertile" "synaptic vesicleOrco.2.642.THsimVP22,antennal lobe glomerulus DM1,chemical conditional,antennal lobe glomerulus DM5,antennal lobe glomerulus DM2,antennal lobe glomerulus VM2" FBgn0015754 Lis-1 Lissencephaly-1 http://flybase.org/reports/FBgn0015754 FBgn0021892 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity enzyme regulator activity ; GO:0030234 | inferred from sequence or structural similarity dynein complex binding ; GO:0070840 | inferred from sequence or structural similarity with UniProtKB:P43034 dynein complex binding ; GO:0070840 | inferred from physical interaction with Dhc64C microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000752735" "protein localization ; GO:0008104 |... mutant phenotype inferred from genetic interaction with Dhc64C <> positive regulation of dendrite morphogenesis ; GO:0050775 |... mutant phenotype <> nuclear migration along microtubule ; GO:0030473 |... genetic interaction with DCTN1-p150 inferred from genetic interaction with Dhc64C <> spindle assembly ; GO:0051225 |... mutant phenotype <> fusome organization ; GO:0045478 |... mutant phenotype <> regulation of dendrite morphogenesis ; GO:0048814 |... mutant phenotype <> cytoplasmic transport, nurse cell to oocyte ; GO:0007303 |... mutant phenotype <> nucleus localization ; GO:0051647 |... mutant phenotype <> germarium-derived oocyte differentiation ; GO:0030706 |... mutant phenotype <> regulation of catalytic activity ; GO:0050790 |... sequence or structural similarity <> nuclear migration ; GO:0007097 |... mutant phenotype <> microtubule-based movement ; GO:0007018 |... sequence or structural similarity <> establishment of mitotic spindle orientation ; GO:0000132 |... biological aspect of ancestor with PANTHER:PTN000752736 <> regulation of microtubule motor activity ; GO:2000574 |... biological aspect of ancestor with PANTHER:PTN000752736 <> dendrite morphogenesis ; GO:0048813 |... mutant phenotype <> dendrite development ; GO:0016358 |... mutant phenotype <> germarium-derived oocyte fate determination ; GO:0007294 |... mutant phenotype <> spermatogenesis ; GO:0007283 |... mutant phenotype <> photoreceptor cell maintenance ; GO:0045494 |... mutant phenotype <> intracellular protein transport ; GO:0006886 |... mutant phenotype <> oocyte nucleus migration involved in oocyte dorsal/ventral axis specification ; GO:0007312 |... mutant phenotype <> neuroblast proliferation ; GO:0007405 |... mutant phenotype <> retrograde axonal transport ; GO:0008090 |... mutant phenotype <> transport along microtubule ; GO:0010970 |... mutant phenotype <> germarium-derived cystoblast division ; GO:0048142 |... mutant phenotype <> protein localization to kinetochore ; GO:0034501 |... mutant phenotype <> regulation of translation by machinery localization ; GO:0043143 |... mutant phenotype <> photoreceptor cell axon guidance ; GO:0072499 |... mutant phenotype <> centrosome separation ; GO:0051299 |... mutant phenotype <> transport ; GO:0006810 |... mutant phenotype <> protein localization ; GO:0008104 |... mutant phenotype <> dorsal appendage formation ; GO:0046843 |... mutant phenotype <> mushroom body development ; GO:0016319 |... mutant phenotype <> oogenesis ; GO:0048477 |... mutant phenotype <> rhabdomere development ; GO:0042052 |... mutant phenotype <> muscle cell cellular homeostasis ; GO:0046716 |... mutant phenotype inferred from genetic interaction with Dys <> intracellular mRNA localization ; GO:0008298 |... mutant phenotype <> regulation of BMP signaling pathway ; GO:0030510 |... direct assay <> kinetochore organization ; GO:0051383 |... mutant phenotype <> vesicle transport along microtubule ; GO:0047496 |... biological aspect of ancestor with PANTHER:PTN000752736 <> stem cell population maintenance ; GO:0019827 |... direct assay <> female germ-line cyst formation ; GO:0048135 |... mutant phenotype <> detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 |... mutant phenotype <> oocyte fate determination ; GO:0030716 |... genetic interaction with BicD <> axo-dendritic transport ; GO:0008088 |... mutant phenotype <> centrosome localization ; GO:0051642 |... mutant phenotype <> border follicle cell migration ; GO:0007298 |... mutant phenotype <> chorion-containing eggshell pattern formation ; GO:0030381 |... mutant phenotype <> mitotic cell cycle checkpoint ; GO:0007093 |... mutant phenotype inferred from genetic interaction with rod <> ovarian fusome organization ; GO:0030723 |... mutant phenotype" kinetochore ; GO:0000776 | inferred from direct assay spindle pole ; GO:0000922 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay dynactin complex ; GO:0005869 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay spindle pole centrosome ; GO:0031616 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay dynein complex ; GO:0030286 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "Lis1, LIS-1, DLis-1, Lis 1, DLIS-1, DLis1, lis1, CG8440, n(2)k11702, l(2R)W8, DLIS1, D-Lis1, Dlis-1, l(2)k13209, Lis-1, lis-1, dLis1, DmLIS1, Dlis1" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR006594:LIS1 homology motif, IPR017252:Dynein regulator LIS1, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like" CG8440 11-Aug-17 DroID_v2017_08 "Drer\pafah1b1b, Drer\pafah1b1a, Drer\tbc1d31" "Scer\PRP4, Scer\PAC1" Cele\lis-1 "Xtro\tbc1d31, Xtro\pafah1b1" "Mmus\Pafah1b1, Mmus\Tbc1d31" "Hsap\PAFAH1B1, Hsap\TBC1D31" " embryonic stage | early , adult stage && oogenesis stage | stage S4-7 , embryonic stage -- adult stage , adult stage , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S10 " " oocyte

, ovary

, germarium | restricted

, nurse cell

" " embryonic stage -- adult stage , adult stage " ovary

"lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,sterile,male sterile,viable,fertile,female sterile,wild-type,neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage" "photoreceptor cell & nucleus,dorsal appendage,spindle,cyst progenitor cell,spindle pole centrosome,spermatocyte,centrosome,spermatid,investment cone,Nebenkern,oocyte,oocyte nucleus,microtubule,egg chamber,nurse cell,supernumerary,microtubule organizing centerJp8),border follicle cell,somatic clone,egg,germline clone,nurse cell fusome,embryonic/larval mushroom body,adult mushroom body,dendrite | somatic clone,dendrite & abdominal dorsal multidendritic neuron ddaC | somatic clone,class IV dendritic arborizing neuron,germline stem cell,spindle | germline clone,cystoblast,germarium,germ band,embryonic/larval brain,centrosome & spermatocyte" FBgn0016047 nompA no mechanoreceptor potential A http://flybase.org/reports/FBgn0016047 FBgn0033617 protein_coding_gene - "sensory perception of sound ; GO:0007605 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype sensory perception of mechanical stimulus ; GO:0050954 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype" extracellular matrix ; GO:0031012 | inferred from direct assay "nomp, CG13207, nompA, NompA, NOMPA, Nomp-A" "IPR001507:Zona pellucida domain, IPR003609:PAN/Apple domain" CG13207 11-Aug-17 DroID_v2017_08 - - "Cele\noah-1, Cele\cutl-27, Cele\C34C12.7, Cele\F32B4.8, Cele\let-653, Cele\cutl-18, Cele\cutl-17, Cele\cutl-28, Cele\T23F1.5, Cele\ZC449.2, Cele\ZC449.1, Cele\H03E18.1, Cele\C16D9.1, Cele\T26C5.2, Cele\noah-2, Cele\R07A4.4, Cele\H42K12.3, Cele\F52C9.5" - - - "wild-type,auditory perception defective,locomotor behavior defective,recessive,uncoordinated,behavior defective,viable" "mechanosensory sensory organ,external sensory organ,eo neuron,sensillum campaniformium & wing vein L3 & adult,dendritic cap cell,Johnston's organ & scolopidium,Johnston's organ & dendritic cap cell,wing,leg,macrochaeta,adult antennal nerve,arista" FBgn0037131 CG14564 - http://flybase.org/reports/FBgn0037131 protein_coding_gene - - - CG14564 IPR032011:Domain of unknown function DUF4794 CG14564 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" FBgn0001391 l(1)2Cc lethal (1) 2Cc http://flybase.org/reports/FBgn0001391 - gene - - - "l(1)VE651, l(1)2Cc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,polyphasic" "ovariole,germline clone,nurse cell,ovary" FBgn0001276 ix intersex http://flybase.org/reports/FBgn0001276 FBgn0033625 protein_coding_gene transcription factor binding ; GO:0008134 | inferred from physical interaction with dsx RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from direct assay female somatic sex determination ; GO:0019101 | traceable author statement somatic sex determination ; GO:0018993 | non-traceable author statement genital disc sexually dimorphic development ; GO:0035263 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay imaginal disc-derived female genitalia morphogenesis ; GO:0048804 | inferred from mutant phenotype negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype sex differentiation ; GO:0007548 | traceable author statement sex determination ; GO:0007530 | inferred from mutant phenotype mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from direct assay "MED29, CG13201, ix, Med29" "IPR021018:Mediator complex, subunit Med29, metazoa" CG13201 11-Aug-17 DroID_v2017_08 Drer\med29 - "Cele\fbxb-15, Cele\fbxb-57, Cele\K10C2.8" Xtro\med29 Mmus\Med29 Hsap\MED29 "visible,heat sensitive,semi-sterile,recessive,sex-determination defective,lethal,female sterile,male semi-sterile,female,male,courtship behavior defective,viable" "anal plate,ectopic,male terminalia,female terminalia,sex comb,female genitalia,male genitalia,tergite,sternite,abdominal tergite 6,female,gonopod long bristle,prothoracic metatarsal segment transverse row bristle,genital arch,lateral plate,penis,female genital disc,male genital disc primordium,heat sensitive,testis,spermatozoon,leg,male" DRSC06325 K -1.210506272 0.094251509 -0.164227534 0.445319919 1.742714767 1.999702295 FBgn0031424 VGlut Vesicular glutamate transporter http://flybase.org/reports/FBgn0031424 protein_coding_gene "L-glutamate transmembrane transporter activity ; GO:0005313 | inferred from sequence alignment with HGNC:16704 inferred by curator from GO:0008021,GO:0035249 transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 neurotransmitter transporter activity ; GO:0005326 | inferred from mutant phenotype L-glutamate transmembrane transporter activity ; GO:0005313 | inferred from sequence alignment with HGNC:16704" "synaptic transmission, glutamatergic ; GO:0035249 | inferred from mutant phenotype transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 L-glutamate transport ; GO:0015813 | inferred from sequence alignment with HGNC:16704 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from genetic interaction with Ih" "integral component of synaptic vesicle membrane ; GO:0030285 | inferred by curator from GO:0008021,GO:0016021 synaptic vesicle membrane ; GO:0030672 | inferred from biological aspect of ancestor with PANTHER:PTN000184252 synaptic vesicle ; GO:0008021 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity vesicle ; GO:0031982 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model" "CG9887, DVGLUT, VGlut, dvglut, DvGluT, vGLUT, VGluT, MFS11, VGLUT, DVGluT, dvGlut, dVGlut, vglut, vGluT, DVGlut, dVGLUT, vGlut, Vglut, dvGluT, DV-Glut, DvGlut" "IPR011701:Major facilitator superfamily, IPR027378:Cyclic nucleotide-regulated ion channel, N-terminal domain, IPR020846:Major facilitator superfamily domain" CG9887 11-Aug-17 DroID_v2017_08 "Drer\slc17a5, Drer\slc17a6b, Drer\slc17a9a, Drer\ppt1, Drer\slc17a6a, Drer\slc17a7a, Drer\slc17a7b, Drer\slc17a8" "Scer\THI73, Scer\YIL166C, Scer\DAL5, Scer\TNA1" "Cele\slc-17.2, Cele\slc-17.6, Cele\vglu-3, Cele\eat-4, Cele\slc-17.1, Cele\vglu-2" "Xtro\slc17a7, Xtro\slc17a6" "Mmus\Slc17a4, Mmus\Slc17a6, Mmus\Slc17a3, Mmus\Slc17a1, Mmus\Slc17a8, Mmus\Slc17a5, Mmus\Slc17a2, Mmus\Slc17a7" "Hsap\SLC17A1, Hsap\SLC17A3, Hsap\SLC17A2, Hsap\SLC17A4, Hsap\SLC17A6, Hsap\SLC17A7, Hsap\SLC17A5, Hsap\SLC17A8" "viable,neurophysiology defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,courtship behavior defective,male,lethal,flightless,uncoordinated,gravitaxis defective,female semi-sterile,fertile,phototaxis defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuromuscular junction,synaptic vesicleBG380,neuromuscular junction,synaptic vesicle,neuropil,antennal lobe,synaptic vesicleVGlut2)" FBgn0026722 drosha drosha http://flybase.org/reports/FBgn0026722 - protein_coding_gene "ribonuclease III activity ; GO:0004525 | inferred from electronic annotation with InterPro:IPR000999, InterPro:IPR011907 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR000999, InterPro:IPR011907 double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity" rRNA catabolic process ; GO:0016075 | inferred from electronic annotation with InterPro:IPR011907 neurogenesis ; GO:0022008 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype primary miRNA processing ; GO:0031053 | inferred from mutant phenotype salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from mutant phenotype - "CG8730, drosha, Drosha, DROSHA" "IPR000999:Ribonuclease III domain, IPR014720:Double-stranded RNA-binding domain, IPR011907:Ribonuclease III" CG8730 11-Aug-17 DroID_v2017_08 Drer\rnasen Scer\RNT1 Cele\drsh-1 Xtro\drosha Mmus\Drosha Hsap\DROSHA "lethal,majority die during prepupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,neurophysiology defective,somatic clone,neuroanatomy defective,majority die during larval stage,recessive,visible,viable" "imaginal disc,eye disc,mushroom body,somatic clone,alpha/beta Kenyon cell,alpha'/beta' Kenyon cell,gamma Kenyon cell,adult antennal lobe projection neuron adPN,oocyte,germline clone,embryonic/larval central nervous system,mushroom body gamma-lobe,adult antennal lobe projection neuron DL1 adPN,eye,embryonic/larval neuroblast,trichogen cell,mesothoracic tergum" DRSC07607 K -0.404120021 0.69733676 -0.479870126 1.08626846 3.117829275 0.943331097 FBgn0010078 RpL23 Ribosomal protein L23 http://flybase.org/reports/FBgn0010078 - protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000218 structural constituent of ribosome ; GO:0003735 | traceable author statement large ribosomal subunit rRNA binding ; GO:0070180 | inferred from biological aspect of ancestor with PANTHER:PTN000205184 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000218 cytoplasmic translation ; GO:0002181 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000218 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "RpL17A, CG3661, L17, Rpl17A, RPL17A, RL17, RpL23, L23, TA01212p, rpl23" "IPR000218:Ribosomal protein L14P, IPR019972:Ribosomal protein L14P, conserved site" CG3661 11-Aug-17 DroID_v2017_08 Drer\rpl23 "Scer\RPL23A, Scer\RPL23B, Scer\MRPL38" Cele\rpl-23 Xtro\rpl23 "Mmus\Rpl23, Mmus\LOC100862455" Hsap\RPL23 embryonic stage -- adult stage "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC04648 IEK -1.925582823 -1.865109659 -1.952796805 -5.500934793 1.243973576 2.38477189 FBgn0051482 CG31482 - http://flybase.org/reports/FBgn0051482 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG2337, CG31482" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034113:Golgi-associated plant pathogenesis-related protein 1, SCP domain" CG31482 11-Aug-17 DroID_v2017_08 "Drer\pi15b, Drer\r3hdml, Drer\glipr2l, Drer\crispld2, Drer\pi15a, Drer\glipr1b, Drer\glipr2, Drer\LOC100536500, Drer\crispld1a, Drer\im:7150988, Drer\crispld1b" "Scer\PRY1, Scer\PRY3, Scer\PRY2" "Cele\F09B9.5, Cele\C07A4.2, Cele\scl-19, Cele\F57B7.2, Cele\C07A4.3, Cele\D2062.1, Cele\scl-1" "Xtro\crisp2, Xtro\crisp3, Xtro\LOC100497187, Xtro\r3hdml, Xtro\MGC108118, Xtro\crisp1, Xtro\crispld2, Xtro\glipr2" "Mmus\R3hdml, Mmus\Crisp1, Mmus\Clec18a, Mmus\Crisp3, Mmus\Crisp4, Mmus\Crispld2, Mmus\Pi15, Mmus\Glipr1l2, Mmus\Crisp2, Mmus\Pi16, Mmus\Glipr1l1, Mmus\Glipr2, Mmus\Crispld1, Mmus\Glipr1" "Hsap\GLIPR2, Hsap\CLEC18A, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\GLIPR1, Hsap\PI15, Hsap\R3HDML, Hsap\PI16, Hsap\CRISP2, Hsap\GLIPR1L1, Hsap\CLEC18C, Hsap\CRISP1, Hsap\CLEC18B, Hsap\CRISPLD1" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC12582 EK 0.168624687 -0.060099751 1.856435593 0.428152346 2.047727519 0.90411248 FBgn0024944 Oamb Octopamine receptor in mushroom bodies http://flybase.org/reports/FBgn0024944 FBgn0040576 protein_coding_gene octopamine receptor activity ; GO:0004989 | inferred from biological aspect of ancestor with PANTHER:PTN000664482 serotonin binding ; GO:0051378 | inferred from biological aspect of ancestor with PANTHER:PTN001955878 octopamine receptor activity ; GO:0004989 | inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity neurotransmitter receptor activity ; GO:0030594 | inferred from biological aspect of ancestor with PANTHER:PTN000664111 G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from biological aspect of ancestor with PANTHER:PTN000664111 "ovulation ; GO:0030728 | inferred from mutant phenotype positive regulation of ovulation ; GO:0060279 | inferred from mutant phenotype G-protein coupled receptor signaling pathway involved in social behavior ; GO:1904068 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | NOT inferred from direct assay adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | inferred from biological aspect of ancestor with PANTHER:PTN001955878 positive regulation of metallopeptidase activity ; GO:1905050 | inferred from mutant phenotype positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway ; GO:0051482 | inferred from direct assay regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype regulation of ovulation ; GO:0060278 | inferred from mutant phenotype cellular calcium ion homeostasis ; GO:0006874 | inferred from direct assay learning ; GO:0007612 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype octopamine or tyramine signaling pathway ; GO:0007211 | inferred from sequence or structural similarity positive regulation of circadian sleep/wake cycle, wakefulness ; GO:0010841 | inferred from mutant phenotype cellular calcium ion homeostasis ; GO:0006874 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0004989 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | non-traceable author statement" "OAMB, Dm-OAMB, Dmoa1, DmOAMB, oamb, Oamb b, Oamb a, DmOCT1B, OAMB-1a, CG15698, CG3856, Oamb, OAMB-K3, OAMB-AS, GPCR, DmOctalpha1Rb, OctR1, OctR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG3856 11-Aug-17 DroID_v2017_08 "Drer\htr5ab, Drer\adra2db, Drer\htr7b, Drer\LOC101884460, Drer\hrh2b, Drer\LOC101885642, Drer\adra2b, Drer\adra2c, Drer\htr5aa, Drer\adra2da, Drer\adra1aa, Drer\htr7a, Drer\htr1aa, Drer\adra2a, Drer\htr1ab, Drer\LOC100536080, Drer\htr7c" - "Cele\dop-4, Cele\ser-3, Cele\ser-6" "Xtro\adra1a, Xtro\adra2a, Xtro\adra2c, Xtro\adra2b" "Mmus\Adra2c, Mmus\Adra2b, Mmus\Adra1a, Mmus\Adra1b, Mmus\Htr5b, Mmus\Htr7, Mmus\Htr5a, Mmus\Hrh2, Mmus\Adra2a, Mmus\Olfr787, Mmus\Htr1a" "Hsap\ADRA2A, Hsap\ADRA1B, Hsap\HTR1A, Hsap\ADRA1A, Hsap\HRH2, Hsap\HTR5A, Hsap\ADRA2C, Hsap\HTR7, Hsap\OR6C74, Hsap\ADRA2B" " adult stage , adult stage | female " " mushroom body

, adult head

, oviduct | restricted

" "female semi-sterile,recessive,courtship behavior defective,male,learning defective,viable,female sterile,sleep defective,female fertile,memory defective" "oviduct,uterus,ovariole" DRSC15120 E -0.378260395 0.242586236 1.843658388 0.658452024 -0.446755209 0.010954094 FBgn0003416 sl small wing http://flybase.org/reports/FBgn0003416 FBgn0011825 protein_coding_gene "signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR016279 phosphatidylinositol phospholipase C activity ; GO:0004435 | inferred from electronic annotation with InterPro:IPR001711, InterPro:IPR016279" "phospholipid catabolic process ; GO:0009395 | inferred from electronic annotation with InterPro:IPR016279 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001192, InterPro:IPR001711 response to insulin ; GO:0032868 | inferred from genetic interaction with Akt1 inferred from genetic interaction with Pi3K92E inferred from genetic interaction with chico inferred from genetic interaction with InR negative regulation of cell differentiation ; GO:0045596 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Sos inferred from genetic interaction with Ras85D inferred from genetic interaction with rl inferred from genetic interaction with Egfr inferred from genetic interaction with vn inferred from genetic interaction with aos inferred from genetic interaction with drk inferred from genetic interaction with spi inferred from genetic interaction with dos border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Raf inferred from genetic interaction with Dsor1" - "PLC, PLCgammaDmel, PLCgamma, CG4200, PLC-gamma, PLC-gamma D, Plcgamma, p145, PLC-gammaD, plc-gammad, sl, PLCgamma1, PLC&ygr;, plc-gamma, DPLCgamma, Sl" "IPR000008:C2 domain, IPR000909:Phosphatidylinositol-specific phospholipase C, X domain, IPR000980:SH2 domain, IPR001192:Phosphoinositide phospholipase C family, IPR001452:SH3 domain, IPR001711:Phospholipase C, phosphatidylinositol-specific, Y domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR016279:Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR011992:EF-hand domain pair" CG4200 11-Aug-17 DroID_v2017_08 "Drer\plcd3a, Drer\plcd4b, Drer\plcg1, Drer\LOC100334276, Drer\si:ch211-260p9.3, Drer\plcg2" Scer\PLC1 "Cele\pll-1, Cele\plc-3, Cele\plc-4" "Xtro\plcg1, Xtro\plcg2" "Mmus\Plcg1, Mmus\Plcl2, Mmus\Plcl1, Mmus\Plcd1, Mmus\Plcd3, Mmus\Plcg2, Mmus\Plcd4" "Hsap\PLCG1, Hsap\PLCD3, Hsap\PLCL2, Hsap\PLCD1, Hsap\PLCD4, Hsap\PLCG2" " embryonic stage , embryonic stage -- adult stage " " anterior midgut proper primordium

, endoderm

, posterior midgut proper primordium

" "visible,viable,fertile,recessive,planar polarity defective,increased cell number,size defective,decreased cell size,somatic clone,dominant,lethal" "wing,ommatidium,photoreceptor cell R7,eye,wing vein,ectopic,interommatidial bristle,eye photoreceptor cell,cone cell,primary pigment cell,supernumerary,wing blade,primary segmental branch,rhabdomere | adult stage | somatic clone,somatic clone" DRSC20377 I 1.606927127 1.194586477 -0.428440558 0.719180748 0.757135179 -1.033673659 FBgn0053113 Rtnl1 Reticulon-like1 http://flybase.org/reports/FBgn0053113 protein_coding_gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype endoplasmic reticulum tubular network membrane organization ; GO:1990809 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype smooth endoplasmic reticulum ; GO:0005790 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "Rtnl1, Retl1, 142893_at, CG8895, G9, CG18623, CG33113, rtnl1, Rtnl-1, Rtn1" IPR003388:Reticulon CG33113 11-Aug-17 DroID_v2017_08 "Drer\rtn2b, Drer\rtn2a, Drer\rtn3, Drer\rtn1a, Drer\rtn1b, Drer\rtn4b, Drer\rtn4a" "Scer\RTN1, Scer\RTN2" Cele\ret-1 "Xtro\rtn1, Xtro\rtn2, Xtro\rtn4, Xtro\rtn3" "Mmus\Rtn4, Mmus\Rtn2, Mmus\Rtn3, Mmus\Rtn1" "Hsap\RTN4, Hsap\RTN1, Hsap\RTN2, Hsap\RTN3" "smell perception defective,viable,behavior defective,recessive,fertile,learning defective,short lived,heat sensitive" "embryonic/larval hemocyte | third instar larval stage,wing,posterior compartment" DRSC00851 K 0.390863167 -0.63775802 -0.140181985 0.475994984 -0.224553958 1.882254429 FBgn0031062 CG14230 - http://flybase.org/reports/FBgn0031062 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype - "cg14230, clone 9.42, anon-18DEe, CG14230, Nol8" IPR000504:RNA recognition motif domain CG14230 11-Aug-17 DroID_v2017_08 Drer\nol8 Scer\NOP8 Cele\K07F5.14 Xtro\nol8 Mmus\Nol8 Hsap\NOL8 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC19586 IE 2.595735414 1.758411778 1.555101871 1.043312794 -1.371202873 1.068996085 FBgn0023172 RhoGEF2 Rho guanine nucleotide exchange factor 2 http://flybase.org/reports/FBgn0023172 "FBgn0010569, FBgn0020519" protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from mutant phenotype Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | traceable author statement "germ-band extension ; GO:0007377 | inferred from mutant phenotype ventral furrow formation ; GO:0007370 | inferred from mutant phenotype actin-mediated cell contraction ; GO:0070252 | inferred from genetic interaction with fog cellularization ; GO:0007349 | inferred from mutant phenotype pole cell development ; GO:0007277 | inferred from mutant phenotype cell elongation involved in imaginal disc-derived wing morphogenesis ; GO:0090254 | inferred from mutant phenotype morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from mutant phenotype anterior midgut invagination ; GO:0007375 | inferred from mutant phenotype regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with LIMK1 actin filament organization ; GO:0007015 | inferred from mutant phenotype gastrulation ; GO:0007369 | traceable author statement spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype inferred from genetic interaction with fog posterior midgut invagination ; GO:0007374 | inferred from mutant phenotype positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from mutant phenotype regulation of myosin II filament organization ; GO:0043519 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | non-traceable author statement" actomyosin contractile ring ; GO:0005826 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay actin cap ; GO:0030478 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "DRhoGEF2, RhoGEF, dRhoGEF2, RhoGef2, DrhoGEF2, DRhoGEF, CG9635, rhoGEF2, dRhoGEF, l(2)04291, T2, Su(Rho1)2B, shar, rhogef2, RhoGEF2, Rho-GEF2, RG2, Gef2, RhoGF2" "IPR000219:Dbl homology (DH) domain, IPR001478:PDZ domain, IPR001849:Pleckstrin homology domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR011993:PH domain-like, IPR015212:Regulator of G protein signalling-like domain, IPR016137:RGS domain" CG9635 11-Aug-17 DroID_v2017_08 "Drer\arhgef1b, Drer\arhgef11, Drer\arhgef12b, Drer\arhgef12a" "Scer\ROM1, Scer\TUS1, Scer\ROM2" Cele\rhgf-1 "Xtro\arhgef12, Xtro\arhgef11" "Mmus\Arhgef11, Mmus\Arhgef12, Mmus\Arhgef1" "Hsap\ARHGEF1, Hsap\ARHGEF12, Hsap\ARHGEF11" embryonic stage | stage <9 organism

"lethal,partially,visible,recessive,rescuable maternal effect,mitotic cell cycle defective,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,cell shape defective,conditional,female sterile,germline clone" "actin filament & embryonic/larval tracheal systembtl.PS,wing,wing disc,embryonic ventral epidermis,rescuable maternal effect,embryonic/first instar larval cuticle,germline clone,maternal effect,ventral,extended germ band embryo,anterior midgut primordium,posterior midgut primordium,blastoderm embryo,pole cell,actin cytoskeleton | blastoderm stage | germline clone,nucleus | blastoderm stage | germline clone,furrow canal,pole cell & cytoskeleton | germ-line clone,ventral midline,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,posterior spiracle primordium,embryonic/larval hemocyte | third instar larval stage,conditional | third instar larval stage,presumptive embryonic salivary gland,somatic clone,epithelial cell,amnioproctodeal invagination,mesectoderm,ventral furrow,stage 5 embryo,stomodeal invagination,mesoderm anlage" DRSC29373 K -0.112535073 -0.320274153 -0.995043335 -0.577791948 0.836836252 1.547629849 FBgn0042641 frc fringe connection http://flybase.org/reports/FBgn0042641 protein_coding_gene UDP-glucose transmembrane transporter activity ; GO:0005460 | NOT inferred from direct assay UDP-xylose transmembrane transporter activity ; GO:0005464 | inferred from direct assay GDP-mannose transmembrane transporter activity ; GO:0005458 | NOT inferred from direct assay antiporter activity ; GO:0015297 | inferred from direct assay UDP-glucuronic acid transmembrane transporter activity ; GO:0005461 | inferred from direct assay UDP-N-acetylglucosamine transmembrane transporter activity ; GO:0005462 | inferred from direct assay UDP-glucose transmembrane transporter activity ; GO:0005460 | inferred from direct assay GDP-fucose transmembrane transporter activity ; GO:0005457 | NOT inferred from direct assay UDP-galactose transmembrane transporter activity ; GO:0005459 | inferred from direct assay UDP-galactose transmembrane transporter activity ; GO:0005459 | NOT inferred from direct assay sensory organ development ; GO:0007423 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype UDP-galactose transport ; GO:0015785 | inferred from direct assay UDP-N-acetylglucosamine transport ; GO:0015788 | inferred from direct assay imaginal disc pattern formation ; GO:0007447 | inferred from mutant phenotype UDP-glucose transport ; GO:0015786 | inferred from direct assay UDP-glucuronic acid transport ; GO:0015787 | inferred from direct assay embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype UDP-xylose transport ; GO:0015790 | inferred from direct assay Golgi medial cisterna ; GO:0005797 | inferred from direct assay "UDP-GlcNAc/UDP-GlcUA, ust74C, UST74C, l(3)10098, l(3)02619, l(3)00073, CG3874, l(3)j2E3, l(3)L6750, l(3)S070006, anon-WO0172774.7, anon-WO0172774.5, frc, FRC, dFRC, Frc" IPR004853:Sugar phosphate transporter domain CG3874 11-Aug-17 DroID_v2017_08 "Drer\slc35d1a, Drer\slc35d1b, Drer\slc35d2, Drer\slc35d3" "Scer\VRG4, Scer\YER039C-A, Scer\HVG1" Cele\sqv-7 "Xtro\slc35d3, Xtro\slc35d1, Xtro\tmem241" "Mmus\Slc35d3, Mmus\Slc35d2, Mmus\Slc35d1, Mmus\Tmem241" "Hsap\TMEM241, Hsap\SLC35D1, Hsap\SLC35D2, Hsap\SLC35D3" "cell polarity defective,lethal,visible,somatic clone,recessive,rescuable maternal effect,segment polarity phenotype,partially,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,some die during second instar larval stage,some die during pupal stage,viable" "wing margin,ectopic,somatic clone,eye,ommatidium,wing vein,macrochaeta,anterior scutellar bristle,anterior postalar bristle,posterior postalar bristle,embryonic/first instar larval cuticle,embryonic segment,mesoderm,germline clone,cuticle,denticle belt,wing,anterior,wing margin bristle,joint,leg,eye photoreceptor cell,presumptive embryonic/larval nervous system,antenna" FBgn0004638 drk downstream of receptor kinase http://flybase.org/reports/FBgn0004638 FBgn0021869 protein_coding_gene sevenless binding ; GO:0005118 | inferred from physical interaction with sev non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein binding ; GO:0005515 | inferred from physical interaction with Dab inferred from physical interaction with Sos protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VZZ9 protein binding ; GO:0005515 | inferred from physical interaction with Cbl protein binding ; GO:0005515 | inferred from physical interaction with Sos SH3/SH2 adaptor activity ; GO:0005070 | non-traceable author statement SH3/SH2 adaptor activity ; GO:0005070 | non-traceable author statement inferred from physical interaction with Sos inferred from physical interaction with sev "Ras protein signal transduction ; GO:0007265 | inferred from sequence or structural similarity with HGNC:4566 inferred from physical interaction with Sos inferred from physical interaction with HGNC:3236 anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 TORC1 signaling ; GO:0038202 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 olfactory learning ; GO:0008355 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 actin filament organization ; GO:0007015 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from mutant phenotype sevenless signaling pathway ; GO:0045500 | traceable author statement positive regulation of MAPK cascade ; GO:0043410 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from biological aspect of ancestor with PANTHER:PTN001231165 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype positive regulation of R7 cell differentiation ; GO:0045678 | inferred from genetic interaction with sev short-term memory ; GO:0007614 | inferred from mutant phenotype activation of JNKK activity ; GO:0007256 | non-traceable author statement sevenless signaling pathway ; GO:0045500 | inferred from genetic interaction with sev inferred from physical interaction with Sos inferred from physical interaction with sev embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype negative regulation of epidermal growth factor-activated receptor activity ; GO:0007175 | inferred from genetic interaction with Cbl" plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 nucleoplasm ; GO:0005654 | inferred from direct assay "downstream of receptor kinase, drk, Drk, Drk/Grb2, DRK, CG6033, Grb2/drk, Su(sev)R1, crkl, E(sev)2B, l(2)k13809, P1112, l(2)10626, 24/1, GRB2, Grb/drk, Grb2, Grb-2" "IPR000980:SH2 domain, IPR001452:SH3 domain" CG6033 11-Aug-17 DroID_v2017_08 "Drer\grb2b, Drer\grb2a, Drer\sh3gl3b, Drer\grap2a, Drer\stam2, Drer\grapb, Drer\grapa, Drer\sh3gl2, Drer\grap2b, Drer\sh3gl1b, Drer\stam" "Scer\SLA1, Scer\HSE1, Scer\PIN3, Scer\LSB1" "Cele\unc-57, Cele\sem-5, Cele\stam-1" "Xtro\grap, Xtro\sla2, Xtro\sla, Xtro\grap2, Xtro\grb2, Xtro\sh3gl1" "Mmus\Sh3gl2, Mmus\Sh3gl1, Mmus\Grb2, Mmus\Stam, Mmus\Grap, Mmus\Rasa1, Mmus\Stam2, Mmus\Grap2, Mmus\Sh3gl3" "Hsap\SH3GL1, Hsap\SH3GL2, Hsap\GRAP2, Hsap\STAM, Hsap\STAM2, Hsap\GRAPL, Hsap\SH3GL3, Hsap\GRAP, Hsap\GRB2" " embryonic stage , larval stage | third instar " " eye-antennal disc

, imaginal disc

" " larval stage | third instar , adult stage , pupal stage " " eye-antennal disc

, photoreceptor cell | presumptive

" "visible,dominant,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,fully,rescuable maternal effect,learning defective,neuroanatomy defective,memory defective" "wing,wing vein,ectopic,posterior,imaginal disc,embryonic/first instar larval cuticle,head,abdomen,intersegmental nerve,anterior fascicle & synapse | supernumerary,macrochaeta,dorsal air sac primordium,somatic clone,abdominal 1 ventral monoscolopidial chordotonal organ vch1,abdominal 2 ventral monoscolopidial chordotonal organ vch1,abdominal 3 ventral monoscolopidial chordotonal organ vch1,abdominal 4 ventral monoscolopidial chordotonal organ vch1,abdominal 5 ventral monoscolopidial chordotonal organ vch1,abdominal 6 ventral monoscolopidial chordotonal organ vch1,abdominal 7 ventral monoscolopidial chordotonal organ vch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,photoreceptor cell R7" DRSC07606 IEK -1.843913625 -4.651346134 -2.640024829 -0.42432868 -1.101126595 -3.522966956 FBgn0000615 exu exuperantia http://flybase.org/reports/FBgn0000615 - protein_coding_gene exonuclease activity ; GO:0004527 | NOT inferred from key residues protein homodimerization activity ; GO:0042803 | inferred from direct assay single-stranded RNA binding ; GO:0003727 | inferred from direct assay "pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype bicoid mRNA localization ; GO:0045450 | traceable author statement bicoid mRNA localization ; GO:0045450 | inferred from expression pattern bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from genetic interaction with mira spermatogenesis ; GO:0007283 | traceable author statement anterior/posterior axis specification, embryo ; GO:0008595 | inferred from genetic interaction with mira ovarian nurse cell to oocyte transport ; GO:0007300 | traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" cytoplasm ; GO:0005737 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay "CG8994, bs30h09.y1, Exu, exu, exu1" - CG8994 11-Aug-17 DroID_v2017_08 - - - - - - " pupal stage , adult stage && oogenesis stage , adult stage | female , adult stage | male , larval stage | late , embryonic stage | early " " germarium

, oocyte

, nurse cell

" " adult stage && oogenesis stage | stage S10 , adult stage && oogenesis stage | stage S7-8 , adult stage && oogenesis stage , spermatogenesis && adult stage " " centripetally migrating follicle cell

, oocyte

, nurse cell

, testis

" "lethal,maternal effect,male sterile,female sterile,viable,fertile,visible,partially lethal - majority die,wild-type,long lived,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,female fertile" "tarsal segment,wing vein,labrum,embryonic head,anterior,embryonic labral segment,embryonic antennal segment,embryonic maxillary segment,embryonic thorax,prothoracic ventral denticle belt,embryonic abdomen,posterior,embryo,embryonic/first instar larval cuticle,cephalic furrow,maternal effect,chaeta,supernumerary" DRSC07615 EK -0.272565888 0.306883623 1.780965503 0.238000339 1.713752638 -0.286602726 FBgn0023518 trr trithorax-related http://flybase.org/reports/FBgn0023518 FBgn0019895 protein_coding_gene histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | inferred from direct assay transcription coactivator activity ; GO:0003713 | inferred from genetic interaction with EcR receptor binding ; GO:0005102 | inferred from physical interaction with EcR inferred from physical interaction with usp protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q94545 "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from genetic interaction with EcR histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype progression of morphogenetic furrow involved in compound eye morphogenesis ; GO:0007458 | inferred from mutant phenotype inferred from genetic interaction with hh response to ecdysone ; GO:0035075 | inferred from direct assay compound eye development ; GO:0048749 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from direct assay positive regulation of hippo signaling ; GO:0035332 | inferred from genetic interaction with sd inferred from genetic interaction with yki positive regulation of histone H3-K9 trimethylation ; GO:1900114 | inferred from mutant phenotype histone methylation ; GO:0016571 | inferred from direct assay" polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay MLL3/4 complex ; GO:0044666 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay "TRR, trr, EG:63B12.3, CG3848, anon-2Bb, Trr" "IPR001214:SET domain, IPR003616:Post-SET domain, IPR003888:FY-rich, N-terminal, IPR003889:FY-rich, C-terminal, IPR034732:Extended PHD (ePHD) domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR015722:Histone-lysine N-methyltransferase Trr" CG3848 11-Aug-17 DroID_v2017_08 "Drer\ehmt2, Drer\kmt2ca, Drer\whsc1l1, Drer\phf20b, Drer\phf20l1, Drer\setd1ba, Drer\suv39h1a, Drer\phf3, Drer\kmt2e, Drer\ehmt1a, Drer\ehmt1b, Drer\whsc1, Drer\suv39h1b, Drer\ash1l, Drer\kmt2d, Drer\nsd1b, Drer\kmt2cb" "Scer\CTI6, Scer\SET2, Scer\SET4, Scer\SET3, Scer\BYE1, Scer\SET1" "Cele\set-32, Cele\C16A11.4, Cele\set-33, Cele\set-21, Cele\set-12, Cele\set-5, Cele\set-9, Cele\set-16, Cele\set-15, Cele\lin-59, Cele\mes-4, Cele\set-26, Cele\met-1, Cele\set-6" "Xtro\kmt2d, Xtro\kmt2c, Xtro\setd1b" "Mmus\Dido1, Mmus\Kmt2c, Mmus\Kmt2b, Mmus\Suv39h1, Mmus\Spocd1, Mmus\Whsc1, Mmus\Whsc1l1, Mmus\Kmt2e, Mmus\Phf3, Mmus\Setd5, Mmus\Phf20l1, Mmus\Setd1b, Mmus\Nsd1, Mmus\Setd1a, Mmus\Kmt2d, Mmus\Ehmt1, Mmus\Ehmt2, Mmus\Suv39h2, Mmus\Setd2, Mmus\Ash1l" "Hsap\PHF20, Hsap\PHF20L1, Hsap\EHMT2, Hsap\NSD1, Hsap\ASH1L, Hsap\SETD2, Hsap\DIDO1, Hsap\KMT2B, Hsap\EHMT1, Hsap\SETD1B, Hsap\KMT2C, Hsap\WHSC1, Hsap\SUV39H2, Hsap\KMT2D, Hsap\KMT2E, Hsap\SETD1A, Hsap\WHSC1L1, Hsap\SETD5, Hsap\SUV39H1" " oogenesis stage | stage >=S10 && adult stage | female , embryonic stage | early , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 8-11 , embryonic stage | stage >=13 , larval stage | third instar , oogenesis stage | stage >=S8 && adult stage | female " " oocyte

,

ubiquitous , mesoderm

, anterior embryonic/larval midgut

, embryonic brain

, ventral nerve cord

, posterior embryonic/larval midgut

, imaginal disc

, embryonic/larval salivary gland

, nurse cell

" "viable,fertile,wild-type,non-enhancer of variegation,non-suppressor of variegation,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "eye,ommatidium,morphogenetic furrow,somatic clone,wing vein" FBgn0035769 CTCF CTCF http://flybase.org/reports/FBgn0035769 protein_coding_gene chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay "maintenance of rDNA ; GO:0043007 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay regulation of gene expression by genetic imprinting ; GO:0006349 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "dCTCF, CG8591, CTCF" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG8591 11-Aug-17 DroID_v2017_08 "Drer\zgc:171551, Drer\znf1068, Drer\si:dkey-154p10.3, Drer\LOC100329723, Drer\si:dkeyp-104f11.6, Drer\znf710a, Drer\znf366, Drer\znf569l, Drer\LOC100537687, Drer\ctcf, Drer\znf1007, Drer\znf1161, Drer\znf1041" Scer\PZF1 "Cele\eor-1, Cele\let-391, Cele\che-1, Cele\Y55F3AM.14, Cele\lin-29, Cele\Y5F2A.4, Cele\fezf-1, Cele\zfp-2, Cele\C28G1.4, Cele\hinf-1" "Xtro\znf710, Xtro\ctcf" "Mmus\Zfp85, Mmus\Zfp37, Mmus\Zfp51, Mmus\Gm3604, Mmus\Zfp184, Mmus\Zfp710, Mmus\Zfp442, Mmus\Zbtb41, Mmus\Gm6710, Mmus\Zfp35, Mmus\Zfp879, Mmus\Zfp7, Mmus\Zfp934, Mmus\Ctcfl, Mmus\Zim1, Mmus\Zfp202, Mmus\Zfp454, Mmus\Zfp583, Mmus\Rex2, Mmus\Gm14432, Mmus\Zfp182, Mmus\Zfp366, Mmus\Zscan2, Mmus\Ctcf, Mmus\Zfp617, Mmus\Zfp229, Mmus\Zfp612, Mmus\Zfp180, Mmus\Zfp26, Mmus\Zfp53, Mmus\Zfp169, Mmus\Zfp758, Mmus\Zfp808, Mmus\Zfp647, Mmus\Zfp629, Mmus\Zbtb40" "Hsap\ZNF268, Hsap\ZNF677, Hsap\ZNF420, Hsap\ZNF530, Hsap\ZNF624, Hsap\ZNF555, Hsap\ZNF582, Hsap\ZNF623, Hsap\CTCFL, Hsap\ZNF71, Hsap\ZNF605, Hsap\ZNF180, Hsap\ZNF571, Hsap\ZNF25, Hsap\ZNF182, Hsap\ZNF568, Hsap\CTCF, Hsap\ZNF300, Hsap\ZNF132, Hsap\ZNF41, Hsap\ZNF234, Hsap\ZNF726, Hsap\ZNF366, Hsap\ZNF585A, Hsap\ZNF835, Hsap\ZNF74, Hsap\ZNF84, Hsap\ZNF567, Hsap\ZNF135, Hsap\ZNF629, Hsap\ZNF613, Hsap\ZNF700, Hsap\ZFP2, Hsap\ZNF534, Hsap\ZNF329, Hsap\ZSCAN2, Hsap\ZNF433, Hsap\ZBTB41, Hsap\ZNF544, Hsap\ZFP37, Hsap\ZBTB40, Hsap\ZNF528, Hsap\ZNF470, Hsap\ZNF112, Hsap\ZNF23" "viable,fertile,enhancer of variegation,non-enhancer of variegation,lethal,recessive,suppressor of variegation,non-suppressor of variegation,partially lethal - majority live,visible,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,some die during pupal stage" "wing,male genitalia,abdominal segment 4,abdominal tergite 5,abdominal sternite 6,abdominal tergite 7,abdominal sternite bristle,abdominal sternite 7,abdominal tergite 7 & abdominal sternite bristle0463),abdominal sternite 6 & abdominal sternite bristle,abdominal tergite 4,abdominal sternite 5,abdominal segment 5,abdominal tergite 7 & abdominal sternite bristle,abdominal sternite 6 & abdominal sternite bristle0463)" FBgn0066120 E(sda)O E(sda)O http://flybase.org/reports/FBgn0066120 gene molecular_function ; GO:0003674 | no biological data available mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E(sda)O, Line O" - - 11-Aug-17 DroID_v2017_08 - - - - - - bang sensitive FBgn0003720 tll tailless http://flybase.org/reports/FBgn0003720 - protein_coding_gene "steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 cell fate specification ; GO:0001708 | traceable author statement mushroom body development ; GO:0016319 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype ring gland development ; GO:0035271 | inferred from mutant phenotype terminal region determination ; GO:0007362 | traceable author statement torso signaling pathway ; GO:0008293 | traceable author statement signal release ; GO:0023061 | inferred from genetic interaction with amon inferred from genetic interaction with Cadps torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor gastrulation ; GO:0007369 | non-traceable author statement cell fate commitment ; GO:0045165 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | non-traceable author statement optic lobe placode development ; GO:0001748 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from genetic interaction with tor Bolwig's organ morphogenesis ; GO:0001746 | traceable author statement anterior/posterior axis specification ; GO:0009948 | traceable author statement neuroblast division ; GO:0055057 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR001723" "tll, NR2E2, Tll, CG1378, TLL, dm-tll, tailless" "IPR013088:Zinc finger, NHR/GATA-type, IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor" CG1378 11-Aug-17 DroID_v2017_08 "Drer\rxrba, Drer\nr0b2a, Drer\vdrb, Drer\nr0b1, Drer\nr2e3, Drer\ppardb, Drer\esrra, Drer\rxrab, Drer\nr2c2, Drer\raraa, Drer\nr2f1a, Drer\nr6a1b, Drer\pparaa, Drer\ar, Drer\esrrga, Drer\nr2c1, Drer\nr3c1, Drer\nr2f1b, Drer\esr2a, Drer\vdra, Drer\nr2f5, Drer\nr0b2b, Drer\pparg, Drer\nr1i2, Drer\rxrbb, Drer\pparab, Drer\nr2f6b, Drer\rxraa, Drer\rarab, Drer\rxrga, Drer\nr2e1, Drer\esr2b, Drer\pparda, Drer\nr2f6a, Drer\nr5a1a, Drer\thrab, Drer\nr2f2, Drer\rargb, Drer\nr1h5, Drer\esrrd, Drer\nr1h4, Drer\esr1, Drer\pgr" - "Cele\fax-1, Cele\nhr-236, Cele\nhr-67" "Xtro\rarb, Xtro\rara, Xtro\esr1, Xtro\nr0b1, Xtro\esr2, Xtro\nr2e3, Xtro\nr3c1, Xtro\nr2f2, Xtro\nr2f1, Xtro\nr2c2, Xtro\nr2f6, Xtro\rarg, Xtro\ar, Xtro\esrrgr, Xtro\esrrg, Xtro\rxra, Xtro\esrrb, Xtro\esrra, Xtro\thrb, Xtro\nr1i2, Xtro\ppard, Xtro\nr2f5, Xtro\rxrg, Xtro\pgr, Xtro\nr1h5, Xtro\nr2e1, Xtro\nr6a1, Xtro\nr3c2, Xtro\pparg, Xtro\vdr, Xtro\ppara, Xtro\nr1h2, Xtro\nr2c1, Xtro\rxrb, Xtro\nr0b2" "Mmus\Esr2, Mmus\Nr1i3, Mmus\Nr0b2, Mmus\Nr0b1, Mmus\Thra, Mmus\Nr2c1, Mmus\Nr2e1, Mmus\Thrb, Mmus\Rxrb, Mmus\Nr3c1, Mmus\Nr2f2, Mmus\Nr2e3, Mmus\Vdr, Mmus\Nr1h2, Mmus\Nr1h4, Mmus\Nr1h5, Mmus\Rarb, Mmus\Pparg, Mmus\Rara, Mmus\Esrrb, Mmus\Rxrg, Mmus\Nr2f1, Mmus\Ppard, Mmus\Esrrg, Mmus\Esr1, Mmus\Rarg, Mmus\Nr2c2, Mmus\Nr3c2, Mmus\Nr2f6, Mmus\Nr1i2, Mmus\Rxra, Mmus\Nr6a1, Mmus\Pgr, Mmus\Nr1h3, Mmus\Ar, Mmus\Ppara, Mmus\Esrra" "Hsap\NR2E1, Hsap\RARB, Hsap\NR2F6, Hsap\NR2C1, Hsap\ESR2, Hsap\THRB, Hsap\AR, Hsap\PPARA, Hsap\NR2F1, Hsap\NR1H4, Hsap\NR2F2, Hsap\NR0B2, Hsap\PPARD, Hsap\NR1H3, Hsap\RXRB, Hsap\NR1H2, Hsap\PGR, Hsap\ESR1, Hsap\NR2E3, Hsap\NR0B1, Hsap\RARA, Hsap\NR1I3, Hsap\PPARG, Hsap\RXRG, Hsap\NR1I2, Hsap\ESRRB, Hsap\ESRRA, Hsap\VDR, Hsap\ESRRG, Hsap\NR3C1, Hsap\NR3C2, Hsap\NR6A1, Hsap\RXRA, Hsap\THRA, Hsap\RARG, Hsap\NR2C2" " embryonic stage | stage 7,8 , embryonic stage , embryonic stage | stage 4 , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | syncytial blastoderm , embryonic stage | stage 15 , embryonic stage | stage 10,11 , embryonic stage | stage 10 , embryonic stage | stage 9,10 , embryonic stage | early , embryonic stage | stage 4-17 , embryonic stage && larval stage " " Pc3 neuroblast

, procephalic neuroblast

, organism | 80-100% egg length

, optic lobe | primoridum

, organism | 70-90% egg length

,

0-20% egg length , Pc2 neuroblast

, visual primordium

,

90-100% egg length , embryonic protocerebral neuromere

, posterior protocerebral neuroblast

, intercalary segment

,

terminal ,

0-10% egg length , posterior deuterocerebral neuromere

, organism | 0-20% egg length

, larval brain

, Pa4 neuroblast

,

posterior , Pa3 neuroblast

, protocerebrum

, organism | 80-90% egg length

, procephalic neurogenic region

, optic lobe

" " embryonic stage | stage 4 , embryonic stage | syncytial blastoderm , embryonic stage | stage 5 " " organism | 80-100% egg length

,

0-20% egg length , organism | 70-90% egg length

, organism | 0-20% egg length

" "lethal,recessive,behavior defective,male limited,neuroanatomy defective,cell cycle defective,wild-type,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially,increased cell death,viable,visible" "embryonic/larval optic lobe,Bolwig organ,anterior protocerebral neuromere,posterior protocerebral neuromere,mushroom body | adult stage,adult mushroom body,brain | larval stage,brain | pupal stage,embryonic small intestine,gonad,embryonic dorsal epidermis,abdominal segment 8,telson,embryo,cephalopharyngeal skeleton,filzkorper,embryonic/larval anus,embryonic/larval posterior spiracle,embryonic/larval hindgut,Malpighian tubule,longitudinal visceral muscle primordium,embryonic abdominal segment 8,anal pad,Malpighian tubule primordium,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,tracheal pit,embryonic hindgut,mushroom body neuroblast,somatic clone,embryonic/larval gut,denticle belt & abdominal segment 8,embryonic brain,embryonic central brain,pars intercerebralis,protocerebrum,ganglion mother cell,corpus cardiacum primordium,embryonic/larval mushroom body,embryonic/larval protocerebrum,presumptive embryonic/larval central nervous system,trichogen cell" FBgn0000448 Hr3 Hormone receptor 3 http://flybase.org/reports/FBgn0000448 "FBgn0019719, FBgn0026805, FBgn0033496" protein_coding_gene "steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 thyroid hormone receptor activity ; GO:0004887 | inferred from electronic annotation with InterPro:IPR001728 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with rig" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 mushroom body development ; GO:0016319 | inferred from mutant phenotype metamorphosis ; GO:0007552 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay regulation of development, heterochronic ; GO:0040034 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "DHR3, CG12208, CG11823, NR1F4, HR3, 2.4, l(2)k09242, Dhr3, D, dHR3, Hr3, 12.6, CG33183, l(2)46CFi, Hr46, hr46, DmRORalpha" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type, IPR001728:Thyroid hormone receptor" CG33183 11-Aug-17 DroID_v2017_08 "Drer\rorcb, Drer\roraa, Drer\rorab, Drer\rorb, Drer\rorca, Drer\rorc" - "Cele\nhr-64, Cele\nhr-85, Cele\nhr-23" "Xtro\rorb, Xtro\rora, Xtro\rorb.2, Xtro\rorc" "Mmus\Rorc, Mmus\Rorb, Mmus\Rora" "Hsap\RORA, Hsap\RORC, Hsap\RORB" " larval stage | first instar , embryonic stage | mid , pupal stage , larval stage | third instar , larval stage | second instar " "developmental rate defective,large body,viable,fertile,female sterile,decreased cell number,cell non-autonomous,partially lethal - majority die,some die during larval stage,lethal,recessive,increased cell death,conditional,lethal - all die before end of embryonic stage,some die during embryonic stage,polyphasic,visible,heat sensitive,somatic clone,neuroanatomy defective" "eye disc,conditional,wing,wing hair,heat sensitive,presumptive embryonic/larval peripheral nervous system,trachea & cuticle,taenidial fold,puparium,adult head,embryonic/larval salivary gland,somatic clone,macrochaeta & adult head | somatic clone,macrochaeta & adult thorax | somatic clone,adult cuticle,macrochaeta,macrochaeta & adult abdomen | somatic clone,macrochaeta & adult abdomen,longitudinal connective,posterior,adult mushroom body,trichogen cell" FBgn0010516 wal walrus http://flybase.org/reports/FBgn0010516 "FBgn0027557, FBgn0027893, FBgn0044469" protein_coding_gene electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000097951 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000097951 electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with UniProtKB:P13803 electron carrier activity ; GO:0009055 | inferred from biological aspect of ancestor with PANTHER:PTN000097951 open tracheal system development ; GO:0007424 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype fatty acid beta-oxidation using acyl-CoA dehydrogenase ; GO:0033539 | inferred from biological aspect of ancestor with PANTHER:PTN000097951 oxidative phosphorylation ; GO:0006119 | inferred from sequence or structural similarity with UniProtKB:P13803 ectodermal digestive tract morphogenesis ; GO:0048567 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity mitochondrial electron transfer flavoprotein complex ; GO:0017133 | inferred from sequence or structural similarity with UniProtKB:P13803 "l(2)02516, BcDNA.LD07532, P447, Etf, EP2253, CG8996, BcDNA:LD07532, BcDNA:GH09945, wal, ETF, ETFA" "IPR018206:Electron transfer flavoprotein subunit alpha, conserved site, IPR001308:Electron transfer flavoprotein alpha subunit/FixB, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR014730:Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, IPR014731:Electron transfer flavoprotein, alpha subunit, C-terminal, IPR033947:Electron transfer flavoprotein, alpha subunit, N-terminal, IPR029035:DHS-like NAD/FAD-binding domain" CG8996 11-Aug-17 DroID_v2017_08 Drer\etfa Scer\AIM45 Cele\F27D4.1 Xtro\etfa Mmus\Etfa Hsap\ETFA "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,maternal effect,neuroanatomy defective,viable" "Malpighian tubule primordium,embryonic Malpighian tubule,embryonic/larval pharynx,embryonic/larval proventriculus,embryonic/larval esophagus,midgut constriction,embryonic head,embryonic/larval trachea,embryonic/first instar larval cuticle,maternal effect,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0002565 Lsp2 Larval serum protein 2 http://flybase.org/reports/FBgn0002565 FBgn0036251 protein_coding_gene - motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay larval serum protein complex ; GO:0005616 | inferred from direct assay "Lsp2, Lsp-2, CG6806, C23, DmeLSP2, LSP-2, LSP 2, Pt-1, LSP2, LHP, CG11538" "IPR000896:Hemocyanin/hexamerin middle domain, IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR008922:Uncharacterised domain, di-copper centre, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set" CG6806 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | second instar -- larval stage | third instar , larval stage | third instar , adult stage " " embryonic/larval fat body

, adult head | restricted

" larval stage | second instar -- larval stage | third instar embryonic/larval fat body

"lethal,recessive,visible" tergite FBgn0035145 MED14 Mediator complex subunit 14 http://flybase.org/reports/FBgn0035145 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR013947 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity intracellular steroid hormone receptor signaling pathway ; GO:0030518 | inferred from biological aspect of ancestor with PANTHER:PTN000301624 mediator complex ; GO:0016592 | inferred from sequence or structural similarity core mediator complex ; GO:0070847 | inferred from physical interaction with MED17 mediator complex ; GO:0016592 | inferred from mutant phenotype "Med14, Trap170, CG12031, p160, dTRAP170, MED14" "IPR013947:Mediator complex, subunit Med14" CG12031 11-Aug-17 DroID_v2017_08 Drer\med14 Scer\RGR1 Cele\rgr-1 Xtro\med14 Mmus\Med14 Hsap\MED14 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC08235 IK -0.817226408 2.553172308 -0.18232037 0.476510348 2.008226034 5.287924467 FBgn0038607 hmw hemingway http://flybase.org/reports/FBgn0038607 protein_coding_gene - sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype motile cilium assembly ; GO:0044458 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception of sound ; GO:0050910 | inferred from mutant phenotype - "anon-WO0140519.198, CG7669, hmw" IPR029488:Hemingway/KIAA1430 CG7669 11-Aug-17 DroID_v2017_08 Drer\cfap97 - - Xtro\cfap97 Mmus\Cfap97 Hsap\CFAP97 "viable,male sterile,female fertile,auditory perception defective,neurophysiology defective" "spermatozoon,spermatid axoneme" FBgn0024592 l(2)k04102 lethal (2) k04102 http://flybase.org/reports/FBgn0024592 - gene - - - "41/2, l(2)k04102" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0044823 Spec2 Spec2 http://flybase.org/reports/FBgn0044823 protein_coding_gene "Rho GTPase binding ; GO:0017048 | inferred from sequence or structural similarity with HGNC:17719,HGNC:18547 structural molecule activity ; GO:0005198 | inferred from biological aspect of ancestor with PANTHER:PTN001004344 structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity with UniProtKB:Q9NRR3" signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001004344 regulation of signal transduction ; GO:0009966 | inferred from sequence or structural similarity with UniProtKB:Q9NRR3 regulation of Rho protein signal transduction ; GO:0035023 | inferred from sequence or structural similarity with HGNC:17719 "cell cortex ; GO:0005938 | inferred from sequence or structural similarity with HGNC:17719,HGNC:18547 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q9NRR3 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001004344" "dSPEC2, dSPEC, SPEC, CG14672, BcDNA:LD24607, Spec2, SPEC2, Spec" IPR000095:CRIB domain CG14672 11-Aug-17 DroID_v2017_08 "Drer\cdc42se2, Drer\cdc42se1" - Cele\F09F7.5 "Xtro\cdc42se1, Xtro\cdc42se2, Xtro\cdc42se2" "Mmus\Cdc42se2, Mmus\Cdc42se1" "Hsap\CDC42SE1, Hsap\CDC42SE2" "viable,fertile" "germline cell,male" FBgn0030240 CG2202 - http://flybase.org/reports/FBgn0030240 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG2202 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR026613:KRAB domain C2H2 zinc finger family" CG2202 11-Aug-17 DroID_v2017_08 "Drer\patz1, Drer\si:ch73-144d13.7, Drer\insm1a, Drer\insm1b, Drer\vezf1b, Drer\zgc:171901, Drer\si:dkey-210j14.3, Drer\zbtb49, Drer\LOC100148466, Drer\si:ch211-161m3.2" "Scer\PZF1, Scer\AZF1" "Cele\Y55F3AM.14, Cele\Y111B2A.10, Cele\Y48G8AL.10" "Xtro\maz, Xtro\vezf1, Xtro\insm2" "Mmus\Zfp689, Mmus\Zfp810, Mmus\Zfp708, Mmus\Zfp28, Mmus\Gm10778, Mmus\Vezf1, Mmus\Zfp738, Mmus\Xaf1, Mmus\2010315B03Rik, Mmus\Zfp146, Mmus\Zfp263, Mmus\Insm2, Mmus\Zfp68, Mmus\Zfp800, Mmus\Patz1, Mmus\Zfp260, Mmus\Insm1, Mmus\Zfp11, Mmus\Zfp937, Mmus\Zbtb49, Mmus\Maz" "Hsap\ZNF260, Hsap\MAZ, Hsap\XAF1, Hsap\VEZF1, Hsap\ZNF502, Hsap\ZNF699, Hsap\ZNF345, Hsap\ZBTB17, Hsap\ZNF69, Hsap\INSM1, Hsap\ZNF471, Hsap\ZNF383, Hsap\ZNF665, Hsap\ZNF146, Hsap\ZNF816, Hsap\ZNF85, Hsap\ZNF263, Hsap\ZNF689, Hsap\ZNF668, Hsap\ZNF449, Hsap\ZNF555, Hsap\ZNF721, Hsap\ZNF846, Hsap\INSM2, Hsap\ZNF439, Hsap\ZSCAN20, Hsap\ZNF470, Hsap\ZNF558, Hsap\ZNF3, Hsap\ZNF778, Hsap\ZNF546, Hsap\ZNF559, Hsap\ZNF836, Hsap\ZNF813" viable DRSC19841 IEK 3.282157117 2.841580072 -2.664796867 -0.144167584 1.690292163 1.124090199 FBgn0033246 ACC Acetyl-CoA carboxylase http://flybase.org/reports/FBgn0033246 protein_coding_gene "acetyl-CoA carboxylase activity ; GO:0003989 | inferred from electronic annotation with InterPro:IPR013537 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR005479, InterPro:IPR011761, InterPro:IPR011764, InterPro:IPR013537, InterPro:IPR013815, InterPro:IPR013816 biotin carboxylase activity ; GO:0004075 | inferred from electronic annotation with InterPro:IPR011764 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011761" fatty acid biosynthetic process ; GO:0006633 | inferred from electronic annotation with InterPro:IPR013537 regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype cellular response to sucrose stimulus ; GO:0071329 | inferred from direct assay regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype regulation of growth ; GO:0040008 | inferred from mutant phenotype triglyceride biosynthetic process ; GO:0019432 | inferred from mutant phenotype regulation of cellular protein localization ; GO:1903827 | inferred from mutant phenotype response to sucrose ; GO:0009744 | inferred from mutant phenotype glycogen metabolic process ; GO:0005977 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG8723, FBgn0043811, DmACC, ACC, CG11198, dACC, A1Z784_DROME, ACoT, Acc" "IPR000089:Biotin/lipoyl attachment, IPR001882:Biotin-binding site, IPR005479:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain, IPR005481:Biotin carboxylase-like, N-terminal domain, IPR005482:Biotin carboxylase, C-terminal, IPR011053:Single hybrid motif, IPR011054:Rudiment single hybrid motif, IPR011761:ATP-grasp fold, IPR011762:Acetyl-coenzyme A carboxyltransferase, N-terminal, IPR011763:Acetyl-coenzyme A carboxyltransferase, C-terminal, IPR011764:Biotin carboxylation domain, IPR013537:Acetyl-CoA carboxylase, central domain, IPR016185:Pre-ATP-grasp domain, IPR034733:Acetyl-CoA carboxylase, IPR029045:ClpP/crotonase-like domain, IPR013815:ATP-grasp fold, subdomain 1" CG11198 11-Aug-17 DroID_v2017_08 "Drer\acacb, Drer\acaca" "Scer\HFA1, Scer\ACC1" "Cele\pod-2, Cele\T28F3.5" "Xtro\acacb, Xtro\acaca" "Mmus\Acacb, Mmus\Acaca" "Hsap\ACACB, Hsap\ACACA" "lethal - all die during larval stage,feeding behavior defective,visible,lethal,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die during embryonic stage,viable,recessive" "embryonic/larval oenocyte | second instar larval stage,embryonic/larval tracheal system | larval stage,embryonic/larval spiracle | larval stage,wing,embryonic/larval brain,embryonic/larval fat body,embryonic/larval oenocyte" DRSC06059 IE -1.446129177 -2.893552572 -1.810274686 2.022327349 0.424030367 -0.579232127 FBgn0011763 Dp DP transcription factor http://flybase.org/reports/FBgn0011763 FBgn0002082 protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | contributes_to inferred from physical interaction with E2f1 sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from physical interaction with E2f1 transcription factor binding ; GO:0008134 | inferred from physical interaction with E2f1 transcription factor binding ; GO:0008134 | inferred from physical interaction with Rbf inferred from physical interaction with Rbf2 DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Rbf" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003316 positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype endomitotic cell cycle ; GO:0007113 | traceable author statement positive regulation of nurse cell apoptotic process ; GO:0045850 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | non-traceable author statement mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | traceable author statement nurse cell apoptotic process ; GO:0045476 | traceable author statement intrinsic apoptotic signaling pathway in response to DNA damage ; GO:0008630 | inferred from mutant phenotype" Rb-E2F complex ; GO:0035189 | inferred from direct assay Myb complex ; GO:0031523 | inferred from direct assay "dDP, DDP1, DP, dDp, DP1, dDP1, DmDP, vr10, l(2)vr10, 49Fk, l(2)49Fk, CG4654, Dp, Dp1, TFPD2, dp" "IPR003316:E2F/DP family, winged-helix DNA-binding domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR015648:Transcription factor DP, IPR014889:Transcription factor DP, C-terminal" CG4654 11-Aug-17 DroID_v2017_08 "Drer\tfdp2, Drer\tfdp1b, Drer\tfdp1a" - Cele\dpl-1 "Xtro\tfdp1, Xtro\tfdp2" "Mmus\Tfdp1, Mmus\Tfdp2" "Hsap\TFDP1, Hsap\TFDP3, Hsap\TFDP2" " larval stage | third instar , embryonic stage | early , embryonic stage " " testis

, spermatocyte

, larval brain

, morphogenetic furrow | anterior to

, morphogenetic furrow | posterior to

, ventral nerve cord

, eye disc

, ventral thoracic disc

, antennal disc

, optic lobe

, embryonic central nervous system

" "viable,fertile,neuroanatomy defective,locomotor behavior defective,cell death defective,wild-type,female sterile,mitotic cell cycle defective,lethal,recessive,lethal - all die before end of pupal stage,visible,some die during pupal stage,decreased cell death,sterile,partially lethal - majority live,germline clone,non-suppressor of variegation,dominant,lethal - all die before end of larval stage,some die during larval stage" "dopaminergic neuron,nurse cell,eye,heterochromatin & nurse cell, with Dpa2,mitotic cell cycle,thorax & macrochaeta,head & macrochaeta,abdomen,wing disc,nucleus,ommatidium,interommatidial bristle,wing vein,macrochaeta,chorion,follicle cell & nucleus,tergite,ovary,heterochromatin & nurse cellvg56),nuclear membrane & nurse cellvg56),polar body nucleus,follicle cell,dorsal appendage,germline clone,egg,embryonic/first instar larval cuticle,nurse cell & actin filament | germ-line clone,ectopic,anterior midgut proper primordium & S phase,eye disc,oocyte,chorion | germline clone,heterochromatin & nurse cell, with Dphs.PD,trichogen cell,mesothoracic tergum" DRSC07402 IEK -3.77733035 -2.912652207 3.79602552 -4.226216377 11.03756704 12.63605456 FBgn0267407 crl courtless http://flybase.org/reports/FBgn0267407 gene - male courtship behavior ; GO:0008049 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "crl, col" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive,courtship behavior defective,male,female fertile,meiotic cell cycle defective" "spermatid,meiotic cell cycle | male" FBgn0030937 CG15042 - http://flybase.org/reports/FBgn0030937 protein_coding_gene - - - CG15042 - CG15042 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "chaeta,supernumerary" FBgn0035598 CG4669 - http://flybase.org/reports/FBgn0035598 protein_coding_gene - - - "anon-WO0140519.194, CG4669" - CG4669 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0044347 l(2)k9 lethal (2) k9 http://flybase.org/reports/FBgn0044347 gene - - - l(2)k9 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0032706 Irk3 Inwardly rectifying potassium channel 3 http://flybase.org/reports/FBgn0032706 protein_coding_gene inward rectifier potassium channel activity ; GO:0005242 | inferred from biological aspect of ancestor with PANTHER:PTN000205946 inward rectifier potassium channel activity ; GO:0005242 | inferred from sequence or structural similarity with Irk1 potassium ion import ; GO:0010107 | inferred from biological aspect of ancestor with PANTHER:PTN000205946 regulation of membrane potential ; GO:0042391 | inferred from sequence or structural similarity with Irk1 wing disc development ; GO:0035220 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from sequence or structural similarity with Irk1 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000205946 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Irk1 "dKirIII, irk3, CG10369, Irk3" "IPR013518:Potassium channel, inwardly rectifying, Kir, cytoplasmic, IPR014756:Immunoglobulin E-set, IPR016449:Potassium channel, inwardly rectifying, Kir" CG10369 11-Aug-17 DroID_v2017_08 "Drer\kcnj11, Drer\kcnj3b, Drer\LOC103910156, Drer\kcnj16, Drer\kcnj14, Drer\kcnj5, Drer\kcnj2a, Drer\kcnj8, Drer\si:ch211-113j13.2, Drer\kcnj12a, Drer\kcnj2b, Drer\kcnj9, Drer\LOC103909814, Drer\kcnj1b, Drer\si:dkey-100n10.2, Drer\kcnj15, Drer\kcnj1a.2, Drer\kcnj1a.4, Drer\zgc:162160, Drer\si:dkey-106c17.3, Drer\kcnj10a, Drer\kcnj13, Drer\kcnj12b, Drer\kcnj1a.5, Drer\kcnj1a.6, Drer\kcnj1a.3, Drer\kcnj11l, Drer\kcnj6, Drer\kcnj1a.1, Drer\kcnj3a" - "Cele\irk-2, Cele\irk-3, Cele\irk-1" "Xtro\kcnj13, Xtro\kcnj10, Xtro\kcnj14, Xtro\kcnj16, Xtro\kcnj2, Xtro\kcnj11, Xtro\kcnj12, Xtro\kcnj1, Xtro\kcnj3, Xtro\kcnj4, Xtro\kcnj9, Xtro\kcnj15" "Mmus\Kcnj3, Mmus\Kcnj4, Mmus\Kcnj1, Mmus\Kcnj16, Mmus\Kcnj10, Mmus\Kcnj14, Mmus\Kcnj8, Mmus\Kcnj9, Mmus\Kcnj12, Mmus\Kcnj6, Mmus\Kcnj15, Mmus\Kcnj11, Mmus\Kcnj5, Mmus\Kcnj13, Mmus\Kcnj2" "Hsap\KCNJ12, Hsap\KCNJ2, Hsap\KCNJ13, Hsap\KCNJ3, Hsap\KCNJ16, Hsap\KCNJ10, Hsap\KCNJ15, Hsap\KCNJ1, Hsap\KCNJ6, Hsap\KCNJ14, Hsap\KCNJ5, Hsap\KCNJ9, Hsap\KCNJ11, Hsap\KCNJ18, Hsap\KCNJ4, Hsap\KCNJ8" "viable,short lived,nutrition conditional,touch sensitivity defective,visible,size defective,partially lethal - majority die,lethal" "wing,wing vein,wing hinge" FBgn0027653 l(1)CL lethal (1) Cell Lethal http://flybase.org/reports/FBgn0027653 - gene - - - "CLX, l(1)CL, l(1)cl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethalcell lethal,somatic clone,lethal,recessive" "eye,somatic clone" FBgn0260345 GSd405 - http://flybase.org/reports/FBgn0260345 gene - - - GSd405 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve" FBgn0051852 Tap42 Two A-associated protein of 42kDa http://flybase.org/reports/FBgn0051852 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from mutant phenotype protein phosphatase inhibitor activity ; GO:0004864 | inferred from genetic interaction with mts regulation of signal transduction ; GO:0009966 | inferred from electronic annotation with InterPro:IPR007304 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype protein phosphatase type 2A complex ; GO:0000159 | inferred from direct assay "Tap-42/CG31852, CG31852, CG6537, Tap42, dTap42" IPR007304:TAP42-like protein CG31852 11-Aug-17 DroID_v2017_08 Drer\igbp1 Scer\TAP42 Cele\ppfr-4 Xtro\igbp1 "Mmus\Igbp1, Mmus\Igbp1b" Hsap\IGBP1 "lethal - all die before end of larval stage,recessive,some die during third instar larval stage,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "spindle,mitosis,embryonic/larval brain,embryonic/larval neuroblast,ganglion mother cell" DRSC24168 K 0.167445607 -0.098296183 0.217375471 -0.517962664 0.154041177 2.605901039 FBgn0041191 Rheb Ras homolog enriched in brain http://flybase.org/reports/FBgn0041191 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from direct assay" "positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype ribosome biogenesis ; GO:0042254 | inferred from direct assay regulation of autophagy ; GO:0010506 | inferred from mutant phenotype cell growth ; GO:0016049 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype positive regulation of ribosome biogenesis ; GO:0090070 | inferred from mutant phenotype apical protein localization ; GO:0045176 | inferred from mutant phenotype negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from expression pattern terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | traceable author statement lipid metabolic process ; GO:0006629 | inferred from mutant phenotype multicellular organism growth ; GO:0035264 | inferred from mutant phenotype carbohydrate metabolic process ; GO:0005975 | inferred from mutant phenotype cholesterol homeostasis ; GO:0042632 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of reactive oxygen species metabolic process ; GO:2000377 | inferred from mutant phenotype" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available "Rheb, CG1081, dRheb, Dm Rheb, rheb, DReb, DmRheb, RHEB, RheB, Q9VND8" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR020849:Small GTPase superfamily, Ras type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1081 11-Aug-17 DroID_v2017_08 "Drer\rasl11b, Drer\ralab, Drer\rap1aa, Drer\hrasa, Drer\rheb, Drer\LOC100332969, Drer\rras2, Drer\ralaa, Drer\ralba, Drer\si:ch73-116o1.2, Drer\rsg1, Drer\zgc:171704, Drer\diras1b, Drer\zgc:152698, Drer\kras, Drer\si:dkeyp-59c12.1, Drer\rit1, Drer\zgc:114118, Drer\rasl12, Drer\hrasb, Drer\rasl11a, Drer\rap1ab, Drer\rrad, Drer\zgc:110699, Drer\nras, Drer\rras, Drer\rasd1, Drer\mras, Drer\rem1, Drer\si:dkey-27j5.5, Drer\ralbb, Drer\diras1a, Drer\rergla, Drer\zgc:153845, Drer\diras2, Drer\rhebl1, Drer\rasl10a, Drer\rap2b, Drer\rap2c, Drer\rap2ab, Drer\rerglb, Drer\zgc:64022, Drer\rem2, Drer\gem" "Scer\RHB1, Scer\RAS1, Scer\RAS2, Scer\RSR1" "Cele\T26C12.3, Cele\rheb-1" "Xtro\rap1b, Xtro\nras, Xtro\rhebl1, Xtro\rap2a, Xtro\diras3, Xtro\rerg, Xtro\rheb, Xtro\kras, Xtro\rem1, Xtro\gem, Xtro\rit1, Xtro\ralb, Xtro\ras-dva, Xtro\rap1a, Xtro\rap2b, Xtro\rergl, Xtro\rasd1, Xtro\diras2, Xtro\hras, Xtro\diras1, Xtro\rsg1, Xtro\rap2c, Xtro\rem2, Xtro\rasd2, Xtro\rasl10a, Xtro\rala, Xtro\rasl11b, Xtro\LOC733456, Xtro\rrad" "Mmus\Rhebl1, Mmus\Nras, Mmus\Gm266, Mmus\Rala, Mmus\Rergl, Mmus\Rem2, Mmus\Rap2b, Mmus\Mras, Mmus\Rasd2, Mmus\Rsg1, Mmus\Rem1, Mmus\Eras, Mmus\Rerg, Mmus\Rap1a, Mmus\Hras, Mmus\Rap1b, Mmus\Rras, Mmus\Diras1, Mmus\Ralb, Mmus\Kras, Mmus\Rrad, Mmus\Rasl11a, Mmus\Rasl11b, Mmus\Rras2, Mmus\Rheb, Mmus\Rit2, Mmus\Rasl12, Mmus\Rasd1, Mmus\Diras2, Mmus\Rasl10a, Mmus\Gem, Mmus\Rap2c, Mmus\Rit1, Mmus\Rasl10b, Mmus\Rap2a" "Hsap\RAP1A, Hsap\DIRAS2, Hsap\MRAS, Hsap\NRAS, Hsap\RAP2B, Hsap\RASD2, Hsap\RERGL, Hsap\RERG, Hsap\DIRAS3, Hsap\RHEB, Hsap\GEM, Hsap\RASL10A, Hsap\RRAS, Hsap\RRAS2, Hsap\HRAS, Hsap\ERAS, Hsap\RAP1B, Hsap\REM1, Hsap\RAP2C, Hsap\RSG1, Hsap\DIRAS1, Hsap\KRAS, Hsap\RIT2, Hsap\REM2, Hsap\RIT1, Hsap\RRAD, Hsap\RASL10B, Hsap\RASL12, Hsap\RASL11B, Hsap\RASL11A, Hsap\RASD1, Hsap\RAP2A, Hsap\RHEBL1, Hsap\RALA, Hsap\RALB" "lethal,recessive,increased cell size,somatic clone,large body,neuroanatomy defective,cell death defective,lethal - all die before end of larval stage,some die during larval stage,small body,cell size defective,developmental rate defective,eclosion rhythm defective,dominant,drug conditional,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,decreased cell size,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,partially lethal - majority die,decreased cell number,visible,chemical sensitive,nutrition conditional,phototaxis defective,neurophysiology defective,mitotic cell cycle defective,increased cell death" "embryonic/larval neuroblast,eye,ommatidium,fat body,somatic clone,synapse796,wing disc,somatic clone | third instar larval stage,embryonic/larval fat body,embryonic/larval hindgut,head,interommatidial bristle,supernumerary,antenna,embryonic/larval neuromuscular junction | third instar larval stage,adult brain,wing,imaginal disc,embryonic/larval salivary gland,ovary,G1 phase,S phase,dorsal compartment,posterior compartment,anterior compartment,photoreceptor cell R7,nutrition conditional,photoreceptor cell R8,embryonic/larval neuromuscular junction,embryonic/larval principal midgut epithelial cell,temperature conditional,intestinal stem cell,photoreceptor cell,salivary gland,conditional,mitotic cell cycle,nucleolusen-e16E,1st posterior cell,rhabdomereGMR.PU" DRSC12148 I -0.508815162 2.423755694 -1.342542655 0.372589988 0.982622258 0.553414123 FBgn0065244 l(2)SH2141 lethal (2) SH2141 http://flybase.org/reports/FBgn0065244 gene - - - "l(2)SH2141, l(2)SH2 2141" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0033167 CG1701 - http://flybase.org/reports/FBgn0033167 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG1701 - CG1701 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0040070 Trx-2 thioredoxin-2 http://flybase.org/reports/FBgn0040070 protein_coding_gene "thioredoxin-disulfide reductase activity ; GO:0004791 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 disulfide oxidoreductase activity ; GO:0015036 | inferred from direct assay oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ; GO:0016671 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 protein-disulfide reductase activity ; GO:0047134 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from biological aspect of ancestor with PANTHER:PTN000047179" glycerol ether metabolic process ; GO:0006662 | inferred from electronic annotation with InterPro:IPR005746 defense response to fungus ; GO:0050832 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype cell redox homeostasis ; GO:0045454 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 nucleus ; GO:0005634 | inferred from direct assay "Trx-2, DmTrx-2, CG3864, dmtrx-2, CG31884, anon-WO0118547.188, DmelTrx-2, 31884, Trx, DTrx-2, TRX2" "IPR005746:Thioredoxin, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site" CG31884 11-Aug-17 DroID_v2017_08 "Drer\txnl1, Drer\txn, Drer\ahnak, Drer\txn2, Drer\zgc:56493" "Scer\TRX3, Scer\TRX1, Scer\TRX2" "Cele\trx-1, Cele\W01B11.6, Cele\trx-4, Cele\Y55F3AR.2, Cele\trx-2, Cele\txl-1, Cele\png-1" "Xtro\txnl1, Xtro\LOC100498224, Xtro\ahnak, Xtro\prx, Xtro\LOC100170420, Xtro\txn, Xtro\nme9" "Mmus\Nme8, Mmus\Txn2, Mmus\Txndc8, Mmus\Txnl1, Mmus\Txndc2, Mmus\Ahnak, Mmus\Ahnak2, Mmus\Txn1" "Hsap\TXNDC2, Hsap\AHNAK, Hsap\NME8, Hsap\TXNDC8, Hsap\TXN, Hsap\AHNAK2, Hsap\TXN2, Hsap\TXNL1" " larval stage , " " imaginal disc

,

" "chemical resistant,immune response defective,long lived,viable,fertile,short lived,locomotor behavior defective,conditional,chemical sensitive,oxidative stress response defective,male fertile" crystal cell FBgn0004569 aos argos http://flybase.org/reports/FBgn0004569 "FBgn0010878, FBgn0011388, FBgn0011502, FBgn0011505, FBgn0011527, FBgn0014382, FBgn0020286" protein_coding_gene epidermal growth factor receptor binding ; GO:0005154 | traceable author statement receptor antagonist activity ; GO:0048019 | non-traceable author statement epidermal growth factor receptor binding ; GO:0005154 | non-traceable author statement receptor antagonist activity ; GO:0048019 | traceable author statement ommatidial rotation ; GO:0016318 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | traceable author statement eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype genital disc development ; GO:0035215 | inferred from mutant phenotype negative regulation of cell fate specification ; GO:0009996 | traceable author statement negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype negative regulation of cell differentiation ; GO:0045596 | traceable author statement negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | non-traceable author statement negative regulation of stem cell differentiation ; GO:2000737 | inferred from genetic interaction with goe imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype oenocyte delamination ; GO:0060233 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype haltere development ; GO:0007482 | inferred from genetic interaction with Egfr inferred from genetic interaction with Ubx eye development ; GO:0001654 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement ovarian follicle cell development ; GO:0030707 | traceable author statement positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype extracellular region ; GO:0005576 | non-traceable author statement extracellular region ; GO:0005576 | traceable author statement extracellular region ; GO:0005576 | inferred from sequence or structural similarity "aos, Aos, rlt, CG4531, gil, sty, arg, Argos, l(3)rQ526, l(3)rJ812, l(3)rJ472, l(3)j5E11, l(3)05959, l(3)05845, argos, DmAos" "IPR021633:Antagonist of EGFR signalling, Argos" CG4531 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , embryonic stage | stage 9-16 , larval stage | third instar " " organism | pair rule

, midline glial cell

, epidermis | ventral

, eye-antennal disc

" "song defective,viable,fertile,partially lethal - majority die,visible,lethal,partially,cell polarity defective,somatic clone,recessive,dominant,wild-type,visual behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,heat sensitive,increased cell death,decreased cell number,increased cell size,size defective,body color defective,some die during pupal stage" "midgut,eye,wing vein L4,dorsal appendage,maternal effect,rhabdomere,eye photoreceptor cell,optic lobe,mystery cell,cone cell,interommatidial bristle & eye | precursor,ommatidium,photoreceptor cell,ectopic,midline glial cell,retina,pigment cell,somatic clone,wing,eye photoreceptor cell & axon,lens,lamina,medulla,lobula,optic nerve,bract,supernumerary,posterior compartment,photoreceptor cell R3,photoreceptor cell R4,ommatidial precursor cluster,posterior,denticle belt,abdominal lateral pentascolopidial chordotonal organ lch5,embryonic/larval oenocyte,dorsal acute muscle,pericardial cell,precursor,dorsal oblique muscle,1st posterior cell,2nd posterior cell,presumptive embryonic/larval central nervous system,chordotonal organ,lateral,photoreceptor cell R8,hypocerebral ganglion,embryonic/larval recurrent nerve,frontal ganglion,embryonic/larval optic lobe,hypostomal sclerite,genital disc primordium,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R5,photoreceptor cell R6,embryonic head,embryonic ventral epidermis,oenocyte primordium,embryonic/larval oenocyte precursor,embryonic/larval brain,embryonic/larval neuroblast,heat sensitive,secondary pigment cell,tertiary pigment cell,Malpighian tubule,wing vein,commissure,ventral nerve cord,maxillary palpus,interommatidial bristle,abdominal sternite bristle,retina & axon,lamina & glial cell,embryonic/larval optic neuropil,mesothoracic dorsal triscolopidial chordotonal organ dch3,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,visual primordium,wing vein L5,mesothoracic tibial bract,mesothoracic tarsal segment 1 & bract-537.4,mesothoracic tibial apical bristle,prothoracic tibial apical bristle,taste bristle & leg | ectopic-537.4,mesothoracic tarsal segment 1 & bract | dorsalDll-md23,mesothoracic tarsal segment 1 & bractDll-md23,adult apodeme & legDll-md23,unguis,taste bristle & leg | ectopicDll-md23,microchaeta & mesothoracic tergum-C253,macrochaeta & mesothoracic tergum-C253,anterior supraalar bristle,posterior supraalar bristle,posterior postalar bristle,anterior postalar bristle,anterior dorsocentral bristle,anterior scutellar bristle,posterior scutellar bristle,anterior crossvein,embryonic/larval salivary gland,Bolwig organ,Bolwig nerve,glial cell & antennal dischs.PB,mesothoracic tergum,wing disc,pretarsus,crossvein,wing vein L3,posterior crossvein,photoreceptor,egg,egg operculum,chorion,micropyle,wing vein L2,chaeta" FBgn0036844 Mkp3 Mitogen-activated protein kinase phosphatase 3 http://flybase.org/reports/FBgn0036844 protein_coding_gene MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | inferred from electronic annotation with InterPro:IPR008343 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement phosphatase activity ; GO:0016791 | inferred from direct assay "mucosal immune response ; GO:0002385 | inferred from mutant phenotype maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from direct assay negative regulation of MAPK cascade ; GO:0043409 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from genetic interaction with Egfr" cytoplasm ; GO:0005737 | inferred from direct assay "Dmkp3, DMKP-3, CG14081, CG14080, Mkp3, MKP3, mkp3, mkp-3, dMKP3" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR001763:Rhodanese-like domain, IPR008343:Mitogen-activated protein (MAP) kinase phosphatase, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like" CG14080 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-184j22.2, Drer\dusp14, Drer\dupd1, Drer\dusp28, Drer\si:ch211-121a2.2, Drer\dusp19a, Drer\si:ch211-203d1.3, Drer\ssh2b, Drer\dusp27, Drer\dusp19b, Drer\dusp1, Drer\zgc:153044, Drer\dusp13a, Drer\dusp4, Drer\si:ch211-195b15.8, Drer\ssh2a, Drer\ssh1a, Drer\ssh1b, Drer\si:dkey-175m17.7, Drer\dusp8b, Drer\zgc:153981, Drer\si:ch211-223p8.8, Drer\dusp8a, Drer\LOC100150565, Drer\dusp6, Drer\dusp2, Drer\dusp3a, Drer\dusp3b, Drer\dusp7, Drer\styx, Drer\dusp5" "Scer\MSG5, Scer\SDP1, Scer\YVH1, Scer\PPS1" "Cele\C04F12.8, Cele\Y54F10BM.13, Cele\F26A3.4, Cele\lip-1, Cele\vhp-1, Cele\F13D11.3" "Xtro\dusp7, Xtro\dusp9, Xtro\dusp18, Xtro\dusp26, Xtro\dusp19, Xtro\dupd1, Xtro\dusp5, Xtro\dusp4, Xtro\dusp1, Xtro\ssh1, Xtro\dusp28, Xtro\ssh2, Xtro\dusp6, Xtro\styx" "Mmus\Dusp13, Mmus\Dusp2, Mmus\Ssh3, Mmus\Dusp1, Mmus\Dusp18, Mmus\Dusp6, Mmus\Ssh2, Mmus\Dusp14, Mmus\Dusp9, Mmus\Dusp7, Mmus\Dusp27, Mmus\Styx, Mmus\Dusp19, Mmus\Ssh1, Mmus\Dusp8, Mmus\Dusp16, Mmus\Dusp28, Mmus\Dusp10, Mmus\Dusp5, Mmus\Dusp4, Mmus\Dusp21, Mmus\Dupd1, Mmus\Dusp3, Mmus\Dusp26" "Hsap\DUPD1, Hsap\DUSP8, Hsap\STYX, Hsap\DUSP6, Hsap\SSH3, Hsap\DUSP13, Hsap\DUSP2, Hsap\DUSP3, Hsap\DUSP18, Hsap\SSH1, Hsap\DUSP4, Hsap\DUSP1, Hsap\DUSP16, Hsap\DUSP19, Hsap\DUSP9, Hsap\DUSP7, Hsap\DUSP14, Hsap\DUSP21, Hsap\SSH2, Hsap\DUSP5, Hsap\DUSP10, Hsap\DUSP27" larval stage | third instar eye disc | posterior to morphogenetic furrow & stripe

"visible,wild-type,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage,cell shape defective,short lived,increased cell death,partially lethal - majority die" "eye,wing vein,supernumerary,eye photoreceptor cell,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R7,ectopic,dorsal branch primordium,photoreceptor cell,midgut,tracheal branch primordium,tracheolar cell,ganglionic branch primordium,embryonic trachea & cortical actin cytoskeletonbtl.PS,adult posterior midgut epithelium,wing vein L2,wing vein L3,wing vein L4,wing vein L5,wing,wing hinge,macrochaeta,mesothoracic tergum" DRSC10085 EK 0.583683296 0.176752916 -1.726001296 -0.337152188 -1.576055112 -0.134120798 FBgn0000137 ase asense http://flybase.org/reports/FBgn0000137 - protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from direct assay inferred from physical interaction with da protein homodimerization activity ; GO:0042803 | inferred from physical interaction with ase transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000358347 DNA binding ; GO:0003677 | inferred from direct assay" epithelial cell proliferation involved in Malpighian tubule morphogenesis ; GO:0061331 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from genetic interaction with ac inferred from genetic interaction with sc regulation of neurogenesis ; GO:0050767 | inferred from biological aspect of ancestor with PANTHER:PTN000358354 central nervous system development ; GO:0007417 | non-traceable author statement chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement chaeta development ; GO:0022416 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype negative regulation of mitotic nuclear division ; GO:0045839 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay RNA polymerase II transcription factor complex ; GO:0090575 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 "Ase, EG:165H7.2, CG3258, T1, T8, AS-T8, as-T8, AS-C T8ase, AS-C T8, ascT8, T1a, sc/T8, ASC, ase, T1A, bHLHc28" "IPR015660:Achaete-scute transcription factor-related, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG3258 11-Aug-17 DroID_v2017_08 "Drer\ascl1b, Drer\mespba, Drer\tal2, Drer\nhlh2, Drer\msgn1, Drer\mespab, Drer\tcf15, Drer\scxa, Drer\figla, Drer\tcf23, Drer\mespaa, Drer\hand2, Drer\ascl1a, Drer\si:ch211-246m6.4, Drer\tcf21, Drer\msc, Drer\lyl1, Drer\tal1, Drer\scxb, Drer\ptf1a, Drer\tcf24" - "Cele\hlh-3, Cele\hlh-14, Cele\hlh-4" "Xtro\hand1, Xtro\mespb, Xtro\tcf15, Xtro\ascl3, Xtro\tcf21, Xtro\ptf1a, Xtro\hand2, Xtro\tal1, Xtro\scx, Xtro\figla, Xtro\ascl2, Xtro\mespa, Xtro\lyl1, Xtro\msc, Xtro\nhlh1, Xtro\msgn1" "Mmus\Ascl2, Mmus\Scx, Mmus\Ascl1, Mmus\Ascl5, Mmus\Nhlh2, Mmus\Tal1, Mmus\Tcf15, Mmus\Hand1, Mmus\Tcf21, Mmus\Ptf1a, Mmus\Mesp1, Mmus\Mesp2, Mmus\Ferd3l, Mmus\Hand2, Mmus\Ascl4, Mmus\Lyl1, Mmus\Msgn1, Mmus\Tal2, Mmus\Msc, Mmus\Tcf23, Mmus\Figla, Mmus\Nhlh1, Mmus\Ascl3" "Hsap\ASCL5, Hsap\TAL1, Hsap\NHLH1, Hsap\ASCL2, Hsap\MESP1, Hsap\FIGLA, Hsap\MSC, Hsap\ASCL1, Hsap\TCF21, Hsap\TCF24, Hsap\PTF1A, Hsap\HAND1, Hsap\TCF23, Hsap\SCX, Hsap\TCF15, Hsap\NHLH2, Hsap\HAND2, Hsap\TAL2, Hsap\ASCL4, Hsap\MESP2, Hsap\ASCL3, Hsap\LYL1, Hsap\MSGN1" " larval stage | third instar , embryonic stage , embryonic stage | stage >=10 , embryonic stage | stage >=11 , embryonic stage | stage 8-11 " " morphogenetic furrow | posterior to

, ganglion mother cell

, embryonic optic lobe primordium

, posterior embryonic/larval midgut

, larval optic lobe

, stage 2 neuroblast

, imaginal disc

, antennal disc

, neuroblast

, procephalic neurogenic region

, sensory mother cell

, labrum

, embryonic/larval midgut

, stage 3 neuroblast

, precursor cell of the stomatogastric nervous system

, larval central nervous system

, embryonic peripheral nervous system

, dorsal mesothoracic disc

, stage 1 neuroblast

, larval optic lobe | anlagen

, ventral thoracic disc

, posterior midgut proper primordium

, eye disc

, embryonic central nervous system

, embryonic ganglion mother cell

, larval brain | restricted

, optic lobe

" " embryonic stage , larval stage | third instar , embryonic stage | stage >=10 " " stage 1 neuroblast

, stage 3 neuroblast

, embryonic ganglion mother cell

, sensory mother cell

, larval optic lobe

, embryonic/larval midgut

, dorsal mesothoracic disc

, stage 2 neuroblast

, larval brain | restricted

, neuroblast

, antennal disc

, ventral thoracic disc

, larval optic lobe | anlagen

" "visible,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,viable" "macrochaeta,heat sensitive,microchaeta,sense organ,external sensory organ,ectopic,wing sensillum,sensillum campaniformium | ectopic & wingC-765,chaeta | ectopic & mesothoracic tergumC-765,mechanosensory chaeta,sensory mother cell,embryonic/larval optic lobe" FBgn0011818 oaf out at first http://flybase.org/reports/FBgn0011818 "FBgn0004866, FBgn0005565" protein_coding_gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - "l(2)22Fb, tnd, l(2)ND1, CG9884, oaf, out at first" IPR026315:Out at first protein CG9884 11-Aug-17 DroID_v2017_08 "Drer\oafb, Drer\oafa" - - Xtro\oaf Mmus\Oaf Hsap\OAF " adult stage && oogenesis stage , larval stage | third instar && spermatogenesis , embryonic stage , oogenesis stage && adult stage | female , embryonic stage | stage >15 , embryonic stage | stage 11 " " oocyte

, spermatocyte

,

ubiquitous , ovary

, gonad

, ventral midline | segmentally repeated

, nurse cell

, embryonic brain

, ventral nerve cord | segmentally repeated

, germ band | restricted

, testis

" "viable,male fertile,female fertile,lethal,recessive,meiotic cell cycle defective,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective" "wing,peripheral nervous system,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,dorsal closure embryo" FBgn0031144 CG1529 - http://flybase.org/reports/FBgn0031144 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG1529 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG1529 11-Aug-17 DroID_v2017_08 "Drer\zgc:101562, Drer\znf668, Drer\znf1169, Drer\si:ch211-241b2.4, Drer\znf1168, Drer\si:ch73-92e7.6, Drer\zgc:162948, Drer\zgc:173548" - "Cele\sdz-12, Cele\Y22D7AL.16, Cele\klu-1, Cele\eor-1" Xtro\znf668 "Mmus\Zfp975, Mmus\Zfp810, Mmus\Zfp189, Mmus\Zfp808, Mmus\Zfp668" "Hsap\ZNF560, Hsap\ZNF668, Hsap\ZNF697" viable FBgn0031282 Pex12 Peroxin 12 http://flybase.org/reports/FBgn0031282 protein_coding_gene "protein C-terminus binding ; GO:0008022 | inferred from electronic annotation with InterPro:IPR017375 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR017375 ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN000306679 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000004628" spermatocyte division ; GO:0048137 | inferred from mutant phenotype protein import into peroxisome matrix ; GO:0016558 | inferred from biological aspect of ancestor with PANTHER:PTN000306679 peroxisome organization ; GO:0007031 | inferred from mutant phenotype protein monoubiquitination ; GO:0006513 | inferred from biological aspect of ancestor with PANTHER:PTN000306679 peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8854 spermatid development ; GO:0007286 | inferred from mutant phenotype peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8854 integral component of peroxisomal membrane ; GO:0005779 | inferred from biological aspect of ancestor with PANTHER:PTN000306679 peroxisomal importomer complex ; GO:1990429 | inferred from biological aspect of ancestor with PANTHER:PTN000306679 "CG3639, pex12, Pex12, DmelPex12, PEX12" "IPR006845:Pex, N-terminal, IPR017375:Peroxisome assembly protein 12, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3639 11-Aug-17 DroID_v2017_08 Drer\pex12 Scer\PEX12 Cele\prx-12 Xtro\pex12 Mmus\Pex12 Hsap\PEX12 "male sterile,developmental rate defective,cytokinesis defective,meiotic cell cycle defective,viable" "spermatid,testis" FBgn0260054 2L2648 - http://flybase.org/reports/FBgn0260054 gene - - - 2L2648 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0037045 CG10584 - http://flybase.org/reports/FBgn0037045 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.713, CG10584" "IPR019410:Lysine methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG10584 11-Aug-17 DroID_v2017_08 "Drer\mettl22, Drer\zgc:92518, Drer\mettl21a, Drer\zgc:172067, Drer\LOC100149425" "Scer\NNT1, Scer\EFM3, Scer\RKM5, Scer\EFM6, Scer\EFM2" "Cele\R08D7.4, Cele\dot-1.2, Cele\C42C1.13, Cele\dot-1.3" "Xtro\mettl21a, Xtro\mettl23, Xtro\mettl22, Xtro\eef2kmt, Xtro\mettl21b" "Mmus\Mettl21b, Mmus\Mettl21c, Mmus\Vcpkmt, Mmus\Eef2kmt, Mmus\Mettl21e, Mmus\Mettl23, Mmus\Mettl22, Mmus\Mettl21a" "Hsap\VCPKMT, Hsap\METTL23, Hsap\METTL21B, Hsap\EEF2KMT, Hsap\METTL21C, Hsap\METTL21A, Hsap\METTL22" viable embryonic/larval hemocyte | third instar larval stage FBgn0004363 porin porin http://flybase.org/reports/FBgn0004363 "FBgn0016759, FBgn0022189, FBgn0024919, FBgn0066003" protein_coding_gene voltage-gated anion channel activity ; GO:0008308 | inferred from direct assay voltage-gated anion channel activity ; GO:0008308 | inferred from sequence or structural similarity with UniProtKB:P21796 anion transmembrane transport ; GO:0098656 | inferred from electronic annotation with InterPro:IPR001925 ion transport ; GO:0006811 | inferred from direct assay phototransduction ; GO:0007602 | inferred from mutant phenotype mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:P21796 sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:P21796 Nebenkern ; GO:0016006 | inferred from direct assay mitochondrial outer membrane ; GO:0005741 | non-traceable author statement lipid particle ; GO:0005811 | inferred from direct assay "CG6647, DmPorin1, POR-1, VDAC, l(2)k05123, DmVDAC, Vdac, anon-WO02059370.56, porin, DVDAC, Porin, cg6647, PORIN, VDAC1" "IPR001925:Porin, eukaryotic type, IPR027246:Eukaryotic porin/Tom40" CG6647 11-Aug-17 DroID_v2017_08 "Drer\LOC101886830, Drer\vdac1, Drer\vdac3, Drer\zgc:56235, Drer\vdac2" "Scer\POR2, Scer\POR1" Cele\vdac-1 "Xtro\vdac3, Xtro\vdac2, Xtro\vdac1" "Mmus\Vdac3, Mmus\Vdac1, Mmus\Vdac2" "Hsap\VDAC1, Hsap\VDAC2, Hsap\VDAC3" "neurophysiology defective,recessive,male fertile,lethal,viable,fertile,short lived,locomotor behavior defective,male sterile,male semi-fertile,female fertile,bang sensitive,female semi-sterile,partially lethal - majority die,some die during larval stage,flight defective" "photoreceptor,mitochondrionMef2.PR,indirect flight muscle,mitochondrion,testis,seminal vesicle,embryonic/larval neuromuscular junction,cystic bulge,waste bag,Nebenkern,mitochondrionBSC143)" FBgn0027499 wde windei http://flybase.org/reports/FBgn0027499 - protein_coding_gene - positive regulation of methylation-dependent chromatin silencing ; GO:0090309 | inferred from mutant phenotype chromosome ; GO:0005694 | inferred from direct assay "CG12340, LD26050, i10, i119, BcDNA:LD26050, Wde, wde" "IPR003961:Fibronectin type III, IPR011990:Tetratricopeptide-like helical domain, IPR013783:Immunoglobulin-like fold, IPR026085:Activating transcription factor 7-interacting protein" CG12340 11-Aug-17 DroID_v2017_08 "Drer\atf7ip, Drer\atf7ip2, Drer\si:ch211-13c6.2" - "Cele\Y82E9BR.23, Cele\pqn-87" - "Mmus\Atf7ip2, Mmus\Atf7ip" "Hsap\ATF7IP2, Hsap\ATF7IP" "female sterile,recessive,lethal - all die before end of P-stage,some die during P-stage,germline clone,viable,visible,female fertile" "ovariole,oocyte,germline clone,trichogen cell" FBgn0027356 Amph Amphiphysin http://flybase.org/reports/FBgn0027356 - protein_coding_gene phospholipid binding ; GO:0005543 | inferred from sequence or structural similarity with HGNC:471 rhabdomere development ; GO:0042052 | inferred from mutant phenotype rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype regulation of muscle contraction ; GO:0006937 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | traceable author statement synaptic vesicle endocytosis ; GO:0048488 | NOT inferred from mutant phenotype exocytosis ; GO:0006887 | traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle endocytosis ; GO:0048488 | NOT inferred from expression pattern inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004148 plasma membrane ; GO:0005886 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay "damph, dAmph, amph, CG8604, Damp, DAMP, Amp, Amph, dAmp" "IPR001452:SH3 domain, IPR003005:Amphiphysin, IPR004148:BAR domain, IPR027267:Arfaptin homology (AH) domain/BAR domain" CG8604 11-Aug-17 DroID_v2017_08 "Drer\amph, Drer\bin3, Drer\bin2b, Drer\bin1b, Drer\bin2a, Drer\LOC563561" "Scer\RVS167, Scer\RVS161" Cele\amph-1 Xtro\bin1 "Mmus\Bin1, Mmus\Bin3, Mmus\Bin2, Mmus\Amph" "Hsap\BIN3, Hsap\AMPH, Hsap\BIN1, Hsap\BIN2" " embryonic stage | stage 17 , embryonic stage | stage 16 , embryonic stage | stage 13 " " embryonic/larval pharynx

, embryonic/larval hindgut

, embryonic epidermis

, embryonic/larval foregut

, embryonic peripheral nervous system

, pharyngeal muscle

" "hypoactive,viable,fertile,neuroanatomy defective,flightless,neurophysiology defective" "anterior fascicle & synapse,macrochaeta,neuromuscular junction | larval stage,rhabdomere,motor neuron,indirect flight muscle,indirect flight muscle & myofibril,T-tubule,NMJ bouton,rhabdomereGMR.PF,rhabdomere | ectopicGMR.PF" DRSC07578 E 0.300095718 -0.242797624 -1.514751064 -0.138475636 0.824212647 -0.082022781 FBgn0033649 pyr pyramus http://flybase.org/reports/FBgn0033649 protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR002209 fibroblast growth factor receptor binding ; GO:0005104 | traceable author statement cardioblast differentiation ; GO:0010002 | inferred from mutant phenotype positive regulation of glial cell proliferation ; GO:0060252 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from mutant phenotype larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from genetic interaction with ths mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype myoblast migration ; GO:0051451 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from mutant phenotype inferred from genetic interaction with ths pericardial nephrocyte differentiation ; GO:0061320 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement - "fgf8-like, FGF8-like2, CG13194, DFGF8-2, pyr, DmPyr, Pyr" "IPR008996:Cytokine IL1/FGF, IPR002209:Fibroblast growth factor family" CG13194 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,cell migration defective,increased cell death" "glial cell,mesoderm,embryonic somatic muscle,embryonic dorsal vessel,embryonic cardioblast,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,segment border muscle,embryonic/larval midgut longitudinal visceral muscle,longitudinal visceral muscle primordium,cell non-autonomous,longitudinal visceral muscle primordium | embryonic stage 12,longitudinal visceral muscle primordium | embryonic stage 13,embryonic/larval midgut longitudinal visceral muscle | embryonic stage 17,embryonic/larval midgut longitudinal visceral muscle | embryonic stage 15,embryonic/larval midgut longitudinal visceral muscle | embryonic stage 14" FBgn0002466 sti sticky http://flybase.org/reports/FBgn0002466 "FBgn0036295, FBgn0062046" protein_coding_gene "protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR000961, InterPro:IPR017892 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR008271 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of cytokinesis ; GO:0032465 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of cytokinesis, actomyosin contractile ring assembly ; GO:2000431 | inferred from direct assay male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype" actomyosin contractile ring ; GO:0005826 | inferred from direct assay "sti, CG10522, dck, cit, l(3)7m62, l(3)7m-62, l(3)SG21, anon-WO0118547.388, Citron K, STI, DCK, CIT-K, sti/Citron" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR001180:Citron homology (CNH) domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017892:Protein kinase, C-terminal" CG10522 11-Aug-17 DroID_v2017_08 "Drer\cita, Drer\rock1, Drer\rock2a, Drer\dzip1, Drer\LOC101882847, Drer\LOC100333880, Drer\si:ch211-89p3.3, Drer\rock2b" "Scer\HSL1, Scer\CBK1, Scer\GIN4" "Cele\F59A6.5, Cele\W02B8.2, Cele\mks-5, Cele\let-502" "Xtro\cdc42bpa, Xtro\cdc42bpb, Xtro\cit, Xtro\rpgrip1, Xtro\rock2, Xtro\mad1l1, Xtro\rock1" "Mmus\Rpgrip1l, Mmus\Rock1, Mmus\Rock2, Mmus\Rpgrip1, Mmus\Cit, Mmus\Cdc42bpg, Mmus\Cdc42bpa, Mmus\Mad1l1" "Hsap\NBPF9, Hsap\MAD1L1, Hsap\NBPF8, Hsap\NBPF20, Hsap\NBPF14, Hsap\ROCK2, Hsap\RPGRIP1, Hsap\CIT, Hsap\NBPF11, Hsap\NBPF3, Hsap\CDC42BPA, Hsap\NBPF15, Hsap\CDC42BPG, Hsap\RPGRIP1L, Hsap\ROCK1, Hsap\NBPF1" "partially lethal - majority die,lethal,cytokinesis defective,lethal - all die before end of P-stage,recessive,some die during P-stage,lethal - all die before end of prepupal stage,some die during prepupal stage,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live,male sterile,female semi-sterile,some die during third instar larval stage,heat sensitive,visible,suppressor of variegation,dominant,female sterile,viable,enhancer of variegation" "presumptive embryonic/larval peripheral nervous system,embryonic peripheral nervous system & neuroniro-2),embryonic/larval brain,imaginal disc,contractile ringiro-2),embryonic/larval neuroblast,neuroblast & chromosome,neuroblast,neuroblast & chromosomeF10),S2 cell-line,neuroblast & condensed chromosome,testis,spermatocyte,chromosome | ectopic,filamentous actin,nucleus,actomyosin contractile ring | ectopic,spermatid & NebenkernE44),spermatid & nucleus | supernumeraryE44),spermatocyte ring canal,spermatid & Nebenkern,spermatid & nucleus | supernumerary,eye,ommatidium,eye & ommatidium,nucleus & follicle cell | conditional - heat sensitive,heat sensitive,interommatidial bristle,nucleusey.PB,follicle cell" FBgn0005583 l(1)dh2 lethal (1) discs heterogeneous 2 http://flybase.org/reports/FBgn0005583 "FBgn0001619, FBgn0001620" gene - - - "l(1)het2, l(1)d.het.-2, l(1)dh2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,cell cycle" FBgn0035572 CG13711 - http://flybase.org/reports/FBgn0035572 protein_coding_gene - regulation of localization ; GO:0032879 | inferred from sequence or structural similarity with halo - "HL5, CG13711" IPR007970:Protein of unknown function DUF733 CG13711 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0001841 l(1)ts1251 lethal (1) ts1251 http://flybase.org/reports/FBgn0001841 - gene - - - l(1)ts1251 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,male sterile" humeral disc FBgn0050271 CG30271 - http://flybase.org/reports/FBgn0050271 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13528, BcDNA:AT17081, CG30271" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG30271 11-Aug-17 DroID_v2017_08 "Drer\hace1, Drer\si:ch211-203b8.6, Drer\tnksa, Drer\ankef1a, Drer\si:ch73-193i2.2, Drer\tnksb, Drer\ank3a, Drer\pidd1, Drer\nfkbiaa, Drer\trpn1, Drer\ank1b, Drer\ankdd1b, Drer\ank2a, Drer\nfkbiab, Drer\ank3b, Drer\ankef1b, Drer\ankdd1a, Drer\si:dkey-86e18.2" - Cele\F34D10.6 "Xtro\ank2, Xtro\ank1, Xtro\hace1, Xtro\ankef1, Xtro\ank3, Xtro\ankdd1a, Xtro\LOC100492885, Xtro\asb7, Xtro\cat2, Xtro\tnks2" "Mmus\Ankrd53, Mmus\Ankdd1b, Mmus\Ankrd60, Mmus\Tnks, Mmus\Asb7, Mmus\Pidd1, Mmus\Ankef1, Mmus\Nfkbib, Mmus\Hace1, Mmus\Ankrd65, Mmus\Nfkbia, Mmus\Ankdd1a, Mmus\Rnasel, Mmus\Ankrd44, Mmus\Ankrd42, Mmus\Tnks2, Mmus\Ank3, Mmus\Ankrd61, Mmus\Ank1, Mmus\Ank2" "Hsap\TNKS, Hsap\ANKEF1, Hsap\PIDD1, Hsap\ANK2, Hsap\ANK1, Hsap\ANKRD65, Hsap\NFKBIA, Hsap\TNKS2, Hsap\ANKRD53, Hsap\ANKDD1B, Hsap\ANKRD61, Hsap\HACE1, Hsap\ANKRD60, Hsap\NFKBIB, Hsap\ANK3, Hsap\RNASEL, Hsap\ANKDD1A, Hsap\ASB7" "viable,partially lethal - majority die,some die during pupal stage" DRSC30044 K -0.085158772 0.273780846 0.228308577 0.531737044 -1.707474229 -0.065409875 FBgn0015391 glu gluon http://flybase.org/reports/FBgn0015391 "FBgn0027863, FBgn0062208" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR010935 DNA binding ; GO:0003677 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with SGD:S000004076 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with SGD:S000004076 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with HGNC:14013 nucleotide binding ; GO:0000166 | inferred from sequence or structural similarity "mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype sister chromatid segregation ; GO:0000819 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from sequence or structural similarity with SGD:S000004076 inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | non-traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype chromosome separation ; GO:0051304 | inferred from genetic interaction with MRG15, Cap-H2 peripheral nervous system development ; GO:0007422 | traceable author statement mitotic sister chromatid segregation ; GO:0000070 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from sequence or structural similarity with SGD:S000004076 inferred from mutant phenotype" condensin complex ; GO:0000796 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay condensin complex ; GO:0000796 | traceable author statement condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:14013 nucleus ; GO:0005634 | inferred from direct assay condensin complex ; GO:0000796 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay condensin complex ; GO:0000796 | inferred from sequence or structural similarity with SGD:S000004076 chromosome ; GO:0005694 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity condensed chromosome ; GO:0000793 | colocalizes_with inferred from direct assay "glu, DmSMC4, SMC4, Gluon, DmSMC4/gluon, l(2)k08819, BcDNA.LD20207, CG11397, BcDNA:LD20207, anon-WO0118547.156, gluon, dSMC4, Smc4, Glu" "IPR003395:RecF/RecN/SMC, N-terminal, IPR010935:SMCs flexible hinge, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024704:Structural maintenance of chromosomes protein" CG11397 11-Aug-17 DroID_v2017_08 Drer\smc4 Scer\SMC4 "Cele\smc-4, Cele\syp-1, Cele\dpy-27" Xtro\smc4 Mmus\Smc4 Hsap\SMC4 "increased cell death,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,non-suppressor of variegation,suppressor of variegation,partially,viable,visible" "adult brain,mitosis & nuclear chromosome,mitotic cell cycle,presumptive embryonic/larval peripheral nervous system,mitotic domain & mitotic anaphase,chromosome,mesothoracic tergum" DRSC03539 I 2.387783831 0.299615719 0.443412305 1.163079801 0.028829645 -0.068903575 FBgn0001776 l(1)M55 lethal (1) M55 http://flybase.org/reports/FBgn0001776 - gene - - - l(1)M55 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0036666 TSG101 Tumor susceptibility gene 101 http://flybase.org/reports/FBgn0036666 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000000514 protein binding ; GO:0005515 | inferred from physical interaction with Vps28 "cellular protein modification process ; GO:0006464 | inferred from electronic annotation with InterPro:IPR008883 protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR008883 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred by curator from GO:0000813 negative regulation of imaginal disc growth ; GO:0045571 | inferred from mutant phenotype maintenance of apical/basal cell polarity ; GO:0035090 | inferred from mutant phenotype negative regulation of growth of symbiont in host ; GO:0044130 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype multivesicular body assembly ; GO:0036258 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype" ESCRT I complex ; GO:0000813 | inferred from direct assay ESCRT I complex ; GO:0000813 | inferred from sequence or structural similarity with SGD:S000000514 "ept, DmTSG101, Tsg101, CG9712, TSG101, dVps23, dTsg101, dTSg101, ESCRT-I, tsg101, vps23, Ept, burs, Tsg1-1" "IPR008883:Ubiquitin E2 variant, N-terminal, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR017916:Steadiness box (SB) domain, IPR011990:Tetratricopeptide-like helical domain" CG9712 11-Aug-17 DroID_v2017_08 "Drer\uevld, Drer\zgc:123278, Drer\tsg101b, Drer\si:dkey-181m9.8, Drer\tsg101a" Scer\STP22 Cele\tsg-101 "Xtro\uevld, Xtro\tsg101" "Mmus\Tsg101, Mmus\Uevld" "Hsap\TSG101, Hsap\UEVLD" "lethal,recessive,partially lethal - majority die,hyperplasia,cell non-autonomous,somatic clone,large body,lethal - all die before end of pupal stage,some die during pupal stage,visible" "eye,somatic clone,head,eye-antennal disc,cell non-autonomous,eye photoreceptor cell,ommatidium,rhabdomere & eye photoreceptor cell | somatic clone,eye disc,oocyte,vesicle,yolk granule,epithelium,interfollicle cell,female germline cyst,wing,terminal tracheal cell,embryonic/larval tracheal system" FBgn0015838 Vang Van Gogh http://flybase.org/reports/FBgn0015838 FBgn0020780 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z6W3 frizzled binding ; GO:0005109 | inferred from physical interaction with fz establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | traceable author statement regulation of establishment of planar polarity ; GO:0090175 | inferred from genetic interaction with dgo establishment of planar polarity ; GO:0001736 | inferred from expression pattern inferred from mutant phenotype positive regulation of axon extension ; GO:0045773 | inferred from genetic interaction with DAAM morphogenesis of a polarized epithelium ; GO:0001738 | inferred from mutant phenotype positive regulation of axon guidance ; GO:1902669 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype inferred from genetic interaction with pk border follicle cell migration ; GO:0007298 | inferred from mutant phenotype dendrite self-avoidance ; GO:0070593 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009539 plasma membrane ; GO:0005886 | inferred from mutant phenotype "stbm, Stbm, strabismus/Van Gogh, vangogh/strabismus, stbm/vang, Vang/Stbm, vang/stbm, stb, CG8075, Vang, Stb, vang" IPR009539:Vang-like protein CG8075 11-Aug-17 DroID_v2017_08 "Drer\vangl2, Drer\vangl1" - Cele\vang-1 Xtro\vangl2 "Mmus\Vangl2, Mmus\Vangl1" "Hsap\VANGL2, Hsap\VANGL1" " pupal stage | >24 hr , pupal stage | <24 hr , larval stage | third instar " " wing

, dorsal mesothoracic disc

" "visible,recessive,planar polarity defective,somatic clone,dominant,heat sensitive,semidominant,cell non-autonomous,viable,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,partially,cell polarity defective" "wing basal cell 1 & wing hair,wing,adult thorax,leg,adult abdomen,tarsal segment,ommatidium,somatic clone,eye photoreceptor cell,wing hair,thorax,pigment cell,abdomen,cell non-autonomous,dorsal wing blade,trichome & adult abdomen | somatic clone,trichome & adult abdomen | somatic clone | cell non-autonomous,embryo,maternal effect,eye,photoreceptor cell R3,photoreceptor cell R4,rhabdomere,cone cell,secondary pigment cell,tertiary pigment cell,macrochaeta & prothoracic segment,mesothoracic bristle,metathoracic bristle,prothoracic leg sensillum,mesothoracic leg sensillum,metathoracic leg sensillum,trichome & adult thorax,trichome & adult head,tarsal segment 2,tarsal segment 3,tarsal segment 4,trichome,trichome & adult abdomen,trichome & pleural membrane,trichome & pleural membrane | somatic clone,trichome & pleural membrane | somatic clone | cell non-autonomous,wing cell,border follicle cell,polar follicle cell,trichome & adult abdomen‘±Tub84B.PL,trichome & adult abdomen | somatic clone‘±Tub84B.PL,trichome & adult abdomen | somatic clone | cell non-autonomous‘±Tub84B.PL,trichogen cell,supernumerary" FBgn0003339 Scr Sex combs reduced http://flybase.org/reports/FBgn0003339 FBgn0002844 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001827, InterPro:IPR017995 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay" "midgut development ; GO:0007494 | traceable author statement sex differentiation ; GO:0007548 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype specification of segmental identity, labial segment ; GO:0007381 | traceable author statement salivary gland boundary specification ; GO:0007432 | non-traceable author statement salivary gland boundary specification ; GO:0007432 | traceable author statement sex comb development ; GO:0045498 | non-traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay sex comb development ; GO:0045498 | inferred from mutant phenotype segment specification ; GO:0007379 | non-traceable author statement" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR017995 "Scr, scr, SCR, Msc, l(3)84Af, CG1030, BG:DS07876.2, DmScr" "IPR017970:Homeobox, conserved site, IPR017995:Homeobox protein, antennapedia type, IPR001356:Homeobox domain, IPR001827:Homeobox protein, antennapedia type, conserved site, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG1030 11-Aug-17 DroID_v2017_08 "Drer\hoxc4a, Drer\hoxa9b, Drer\mnx2a, Drer\hoxa1a, Drer\hoxb4a, Drer\gsx1, Drer\pdx1, Drer\hoxb1a, Drer\hoxb6a, Drer\hoxa3a, Drer\hoxb3a, Drer\hoxb8b, Drer\gsx2, Drer\hoxc1a, Drer\hoxc6b, Drer\hoxd4a, Drer\hoxa2b, Drer\hoxd3a, Drer\hoxb8a, Drer\hoxb7a, Drer\hoxb2a, Drer\meox2a, Drer\hoxc5a, Drer\meox1, Drer\gbx2, Drer\hoxb5b, Drer\hoxb1b, Drer\meox2b, Drer\hoxc8a, Drer\hoxc6a, Drer\hoxb5a, Drer\gbx1, Drer\hoxa5a, Drer\hoxa4a, Drer\hoxb6b, Drer\mnx1, Drer\hoxc3a" "Scer\PHO2, Scer\YOX1, Scer\YHP1" "Cele\mab-5, Cele\lin-39" "Xtro\gbx2.2, Xtro\hoxc5, Xtro\hoxc3, Xtro\hoxb5, Xtro\hoxa5, Xtro\hoxd8, Xtro\hoxb4, Xtro\hoxb7, Xtro\pdx1, Xtro\hoxd3, Xtro\hoxa2, Xtro\gbx2.1, Xtro\hoxb1, Xtro\gsx1, Xtro\hoxb2, Xtro\hoxa3, Xtro\gsx2, Xtro\meox2, Xtro\hoxd1, Xtro\hoxb6, Xtro\hoxa1, Xtro\hoxb3, Xtro\hoxb8, Xtro\mnx1, Xtro\hoxc8, Xtro\hoxc4" "Mmus\Hoxd4, Mmus\Hoxd1, Mmus\Hoxc8, Mmus\Hoxa5, Mmus\Hoxb5, Mmus\Hoxa1, Mmus\Hoxb8, Mmus\Hoxb6, Mmus\Hoxc5, Mmus\Mnx1, Mmus\Gbx1, Mmus\Hoxb4, Mmus\Hoxb7, Mmus\Hoxa2, Mmus\Hoxb3, Mmus\Hoxb1, Mmus\Pdx1, Mmus\Hoxc4, Mmus\Hoxa3, Mmus\Hoxb2, Mmus\Gsx2, Mmus\Hoxa7, Mmus\Gsx1, Mmus\Hoxc6, Mmus\Gbx2, Mmus\Hoxd3, Mmus\Meox2, Mmus\Hoxd8, Mmus\Hoxa6, Mmus\Meox1, Mmus\Hoxa4" "Hsap\MEOX1, Hsap\HOXC4, Hsap\MEOX2, Hsap\GBX1, Hsap\HOXC8, Hsap\GSX1, Hsap\HOXB2, Hsap\HOXA4, Hsap\HOXA7, Hsap\GSX2, Hsap\HOXA1, Hsap\HOXB8, Hsap\HOXD3, Hsap\HOXD1, Hsap\HOXD4, Hsap\GBX2, Hsap\HOXB3, Hsap\HOXB6, Hsap\MNX1, Hsap\HOXC6, Hsap\HOXA6, Hsap\HOXB7, Hsap\HOXA2, Hsap\HOXA3, Hsap\HOXB4, Hsap\HOXA5, Hsap\HOXB1, Hsap\HOXD8, Hsap\HOXC5, Hsap\PDX1, Hsap\HOXB5" " embryonic stage | 6.2-7.2 hr , embryonic stage | stage 11-17 , larval stage , embryonic stage , embryonic stage | >10.2-11.2 hr , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | stage 10 , embryonic stage | 2.5-3.1 hr , embryonic stage | stage 9,10 , embryonic stage--pupal stage , embryonic stage | cellular blastoderm , embryonic stage | stage 14 " " ectoderm &&of embryonic labial segment

, embryonic labial segment

, labial disc

, embryonic brain

, ventral nerve cord | restricted

, ectoderm &&of embryonic prothoracic segment | restricted

, mesoderm &&of embryonic prothoracic segment

, embryonic central nervous system | restricted

, adepithelial cell of dorsal mesothoracic disc

, dorsal prothoracic disc

, embryonic myoblast &&of embryonic prothoracic segment

, adepithelial cell of ventral mesothoracic disc

, embryonic prothoracic segment

, parasegment 4 | anterior

{ + tsh-, Antp*, Df(3R)P9 } , ventral prothoracic disc

, embryonic central nervous system

, ventral mesothoracic disc | restricted

, labial segment

, cephalic furrow | posterior to

, ectoderm &&of parasegment 2

, prothoracic segment

, parasegment 3

{ + tsh-, Antp* } , embryonic subesophageal neuromere

, embryonic/larval pharynx

, parasegment 3

{ + tsh-, Antp*, Df(3R)P9 } , mesoderm &&of parasegment 3

, visceral mesoderm &&of anterior embryonic/larval midgut

, prothoracic segment &&of ectoderm | ventral

, parasegment 2

, dorsal mesothoracic disc | restricted

, subesophageal ganglion

, larval central nervous system

, embryonic nervous system

, parasegment 3

, visceral mesoderm &&of posterior embryonic/larval midgut

, parasegment 4 | anterior

" " embryonic stage , embryonic stage | stage 13-17 , embryonic stage | extended germ band , embryonic stage | >7.2 hr , embryonic stage | stage 11,12 , embryonic stage | stage 13-14 , embryonic stage | stage >13 , larval stage | third instar ,, embryonic stage | late extended germ band , larval stage , embryonic stage | stage 11-12 , embryonic stage | stage >14 , embryonic stage | stage 8 , embryonic stage | stage 6 , embryonic stage | stage 5 , embryonic stage | stage 13-15 , embryonic stage | stage 17 , embryonic stage | mid-late , embryonic stage | stage 12-14 , embryonic stage | >6.2-7.2 hr , adult stage , embryonic stage | stage 16 , embryonic stage | stage 13 " " posterior embryonic/larval midgut

, visceral mesoderm

, cephalic furrow | posterior to

, visceral mesoderm

{ - ftz*/prd* } , visceral mesoderm

{ 0 run* } , visceral mesoderm

{ v Antp- } , prothoracic segment

, labial segment

, visceral mesoderm &&of embryonic/larval midgut &&ofparasegment 4

, epidermis &&of prothoracic segment

, labial disc

, parasegment 4 visceral mesoderm

{ $ ftz* } , visceral mesoderm

{ - opa* } , ectoderm &&of embryonic prothoracic segment

, visceral mesoderm

{ $ kni* } , ventral thoracic disc

{ - Pc3/brm2 } , prothoracic segment &&of ectoderm

, visceral mesoderm &&of anterior embryonic/larval midgut

, ventral thoracic disc

, parasegment 3

, visceral mesoderm

{ 0 en* } , visceral mesoderm

{ $ eve4 } , embryonic/larval salivary gland

, subesophageal ganglion

, visceral mesoderm &&of posterior embryonic/larval midgut

, visceral mesoderm

{ - eve3 } , embryonic labial segment &&of ectoderm

, parasegment 2--4

, visceral mesoderm

{ - opa*/prd* } , ectoderm | restricted

, embryonic subesophageal neuromere

, parasegment 2 &&of ectoderm

, ventral nerve cord | restricted

, visceral mesoderm

{ 0 odd* } , hypostomal sclerite | ventral to

, parasegment 3 &&of embryonic central nervous system

, epidermis &&of labial segment

, maxillary segment | posterior

, gastric caecum

, dorsal ridge

, visceral mesoderm

{ 0 prd* } , parasegment 2

, visceral mesoderm

{ $ Kr* } , prothoracic segment | anterior

, visceral mesoderm

{ 0 wg* } , visceral mesoderm

{ 0 h* } , ectoderm &&of embryonic labial segment

, visceral mesoderm

{ - hb* } , parasegment 2 &&of embryonic central nervous system

, visceral mesoderm

{ 0 odd*/eve* } , ventral prothoracic disc

, dorsal thoracic disc

, embryonic central nervous system | restricted

, parasegment 2,3 &&of embryonic central nervous system

, prothoracic segment | lateral

" "visible,dominant,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,homeotic,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,polyphasic,viable,somatic clone,cold sensitive,partially,wild-type,some die during pupal stage" "sex comb,pseudotrachea,metathoracic leg,male,ectopic,mesothoracic leg,prothoracic leg,mesothoracic leg & sex comb | ectopic,metathoracic leg & sex comb | ectopic,mesothoracic leg & sex comb | ectopic | conditional ts,T1 beard,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic thoracic segment,embryonic head,embryonic/larval salivary gland,supernumerary,third segment of antenna,arista,tarsal segment,eye,mesothoracic leg & sex comb | ectopic, with Dp(3;Y)77ab,metathoracic leg & sex comb | ectopic, with Dp(3;Y)77ab,antenna,adult salivary gland primordium,heat sensitive,larval mesothoracic segment,larval metathoracic segment,adult head,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,prothoracic ventral denticle belt,cephalopharyngeal skeleton,maxillary palpus,labellum,occiput,larval head,dorsal closure embryo,prothoracic segment,adult labial segment,labial segment,salivary gland imaginal ring,proboscis,pronotum,somatic clone,sex comb tooth,labial disc,embryonic/larval labial organ,haltere,metathoracic laterotergite,wing,scutum,embryonic prothoracic segment,embryonic labial segment,presumptive embryonic/larval peripheral nervous system,distal,mesothoracic leg & sex comb | ectopic77ab), with Df(3R)Scr,metathoracic leg & sex comb | ectopic77ab), with Df(3R)Scr,cell autonomous,sternopleural bristle,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,cold sensitive,salivary gland,metathoracic tarsal bristle transverse row,prothoracic tarsal segment,mesothoracic tarsal segment,metathoracic tarsal segment,pretarsus,prothoracic ventral intersegmental muscle,metathoracic ventral acute muscle,embryonic/larval midgut primordium,embryonic gastric caecum & parasegment 3how-24B,embryonic gastric caecum & parasegment 7how-24B,midgut chamber 2,gastric caecum primordium,embryonic tritocerebrum,mesothoracic tergum" FBgn0020386 Pdk1 Phosphoinositide-dependent kinase 1 http://flybase.org/reports/FBgn0020386 FBgn0035098 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000683254" negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | traceable author statement female gamete generation ; GO:0007292 | traceable author statement positive regulation of cell growth ; GO:0030307 | non-traceable author statement sex differentiation ; GO:0007548 | traceable author statement response to ethanol ; GO:0045471 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of cell size ; GO:0045793 | inferred from genetic interaction with gig regulation of cell growth ; GO:0001558 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | traceable author statement cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | non-traceable author statement cell surface receptor signaling pathway ; GO:0007166 | inferred from genetic interaction with Pi3K92E positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype regulation of organ growth ; GO:0046620 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 cytosol ; GO:0005829 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:O15530 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:O15530 neuromuscular junction ; GO:0031594 | inferred from direct assay "PDK1/Pk61C, PDK, PDK1, dSTPK61, Pdk1, DSTPK61, Dstpk61, CG1210, PDK-1, dPDK1, CG1201, dPDK-1, Pk61C/PDK1, pk61c, Pk61C, PK61C, 1210, Pk61c/PDK1, Pk61C|PDK1, dPDK, pdk1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011993:PH domain-like, IPR017441:Protein kinase, ATP binding site, IPR033931:PDK1-type, PH domain" CG1210 11-Aug-17 DroID_v2017_08 "Drer\pdpk1a, Drer\pdpk1b" "Scer\PKH1, Scer\CDC15, Scer\PKH3, Scer\PKH2" "Cele\W04B5.5, Cele\pdk-1" Xtro\pdpk1 Mmus\Pdpk1 Hsap\PDPK1 "partially lethal - majority die,small body,neuroanatomy defective,lethal,recessive,chemical resistant,male limited,viable,male sterile,developmental rate defective,decreased cell size,somatic clone,cell autonomous,visible,increased cell size,chemical sensitive,increased cell death,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "motor neuron,NMJ bouton,embryonic/larval neuromuscular junction,supernumerary | third instar larval stage,macrochaeta,eye,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,adult head,wing disc,somatic clone,wing,embryonic/larval neuroblast,ommatidium,germline cell,male,embryonic ventral epidermis" DRSC08682 IEK -0.829272514 2.353649497 -1.292842261 -1.88418029 0.232151716 1.806230039 FBgn0004650 fs(1)N female sterile (1) Nasrat http://flybase.org/reports/FBgn0004650 "FBgn0000750, FBgn0000914, FBgn0024367" protein_coding_gene heparin binding ; GO:0008201 | inferred from biological aspect of ancestor with PANTHER:PTN001116154 "anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement terminal region determination ; GO:0007362 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern eggshell chorion assembly ; GO:0007306 | non-traceable author statement vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity germline ring canal ; GO:0045172 | inferred from direct assay vitelline envelope ; GO:0060388 | inferred from direct assay external side of plasma membrane ; GO:0009897 | inferred from direct assay "fs(1)N, fs(1)Nasrat, fs(1)Nas, CG11411, 8D8.1, EG:8D8.1, fs(1)K1540, fs(1)A371, fs(1)M6, 371, fs(1)[nas], Nas, Fs(1)N, nas" IPR015943:WD40/YVTN repeat-like-containing domain CG11411 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Bsph2, Mmus\Bsph1" "Hsap\BSPH1, Hsap\ELSPBP1" "female sterile,neuroanatomy defective,female sterile soma-dependent,recessive,terminal phenotype,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,wild-type,heat sensitive,female sterile germline-dependent,viable" "vitelline membrane,intersegmental nerve,anterior fascicle & synapse | supernumerary,anterior fascicle & synapse,egg,cephalopharyngeal skeleton,maternal effect,head,anterior,telson,abdominal segment 8,ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 9,abdominal segment 10,labrum,ocular segment,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic telson,proctodeum,wing vein L2,wing vein L3,oocyte" FBgn0000327 clv-1 cloven thorax 1 http://flybase.org/reports/FBgn0000327 - gene - - - clv-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,partially lethal - majority die,cold sensitive" adult thorax FBgn0003660 Syb Synaptobrevin http://flybase.org/reports/FBgn0003660 "FBgn0005620, FBgn0019711, FBgn0023032" protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 SNAP receptor activity ; GO:0005484 | non-traceable author statement SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 "vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 vesicle-mediated transport ; GO:0016192 | non-traceable author statement synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity neurotransmitter secretion ; GO:0007269 | non-traceable author statement lumen formation, open tracheal system ; GO:0035149 | traceable author statement" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001388 synaptic vesicle ; GO:0008021 | non-traceable author statement plasma membrane ; GO:0005886 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 "syb, CG12210, c-Syb, VAMP, Vamp, 21.15, J, l(2)46CFq, l(2)46El, Syb, dVAMP, SYB, VAMP2, synaptobrevin, END1-2" IPR001388:Synaptobrevin CG12210 11-Aug-17 DroID_v2017_08 "Drer\vamp8, Drer\vamp3, Drer\zgc:92912, Drer\sec22c, Drer\sec22ba, Drer\vamp1, Drer\vamp4, Drer\sybl1, Drer\vamp2, Drer\vamp5, Drer\sec22a, Drer\sec22bb" "Scer\NYV1, Scer\SNC1, Scer\SNC2" "Cele\vamp-7, Cele\sec-22, Cele\snb-2, Cele\vamp-8, Cele\snb-6, Cele\snb-5, Cele\snb-7, Cele\snb-1" "Xtro\sec22a, Xtro\sec22b, Xtro\vamp3, Xtro\vamp1, Xtro\vamp7, Xtro\sec22c, Xtro\vamp2, Xtro\vamp4, Xtro\ykt6" "Mmus\Vamp1, Mmus\Vamp5, Mmus\Vamp7, Mmus\Sec22c, Mmus\Vamp3, Mmus\Sec22b, Mmus\Vamp4, Mmus\Vamp8, Mmus\Sec22a, Mmus\Ykt6, Mmus\Vamp2" "Hsap\SEC22B, Hsap\YKT6, Hsap\VAMP7, Hsap\VAMP1, Hsap\VAMP2, Hsap\VAMP8, Hsap\VAMP5, Hsap\VAMP3, Hsap\SEC22C, Hsap\VAMP4" " adult stage , embryonic stage | stage 13 , embryonic stage | early , embryonic stage -- adult stage , embryonic stage | extended germ band , embryonic stage | contracted germ band " " pupal/adult digestive system

, Malpighian tubule primordium

, adult head

, inclusive hindgut primordium

, posterior midgut proper primordium

, anterior midgut proper primordium

, stomodeum

" "lethal,recessive,cell lethalcell lethal,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "eye,somatic clone,ommatidium,embryonic/larval tracheal system" FBgn0024754 Flo1 Flotillin 1 http://flybase.org/reports/FBgn0024754 - protein_coding_gene structural molecule activity ; GO:0005198 | non-traceable author statement - plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay flotillin complex ; GO:0016600 | non-traceable author statement "FLO1, Flo[Dm], reggie-2, CK02126, FLO[Dm], CG8200, flo, flo1, Flo1, Flo, FLO[Dm]-1, flotillin, Flo-1" "IPR001107:Band 7 domain, IPR027705:Flotillin family, IPR031905:Flotillin, C-terminal domain" CG8200 11-Aug-17 DroID_v2017_08 "Drer\flot1b, Drer\flot1a, Drer\flot2b, Drer\flot2a" - - "Xtro\flot2, Xtro\flot1" "Mmus\Flot2, Mmus\Flot1" "Hsap\FLOT2, Hsap\FLOT1" embryonic stage | stage >=12 " ventral nerve cord

, embryonic brain

" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC28122 K -0.388800432 -0.179426376 -0.03545058 0.459484138 -2.492884144 -0.178372016 FBgn0250788 beta-Spec beta Spectrin http://flybase.org/reports/FBgn0250788 protein_coding_gene "actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR016343 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR016343 actin binding ; GO:0003779 | inferred from sequence or structural similarity cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity microtubule binding ; GO:0008017 | inferred from direct assay ankyrin binding ; GO:0030506 | inferred from direct assay phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from direct assay" axon guidance ; GO:0007411 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype maintenance of presynaptic active zone structure ; GO:0048790 | inferred from direct assay negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype long-term strengthening of neuromuscular junction ; GO:0042062 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype plasma membrane organization ; GO:0007009 | traceable author statement photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype spectrin ; GO:0008091 | inferred from electronic annotation with InterPro:IPR016343 fusome ; GO:0045169 | inferred from direct assay spectrosome ; GO:0045170 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | traceable author statement axon ; GO:0030424 | inferred from direct assay spectrin ; GO:0008091 | inferred from sequence or structural similarity neuromuscular junction ; GO:0031594 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "beta-Spec, beta-spec, Spec, kus, b-Spec, i168, i6, CG5870, betaspec, betaSpec, SPEC8, beta, Spec-beta, Specbeta, l(1)G0074, l(1)G0198, l(1)G0108, anon-EST:fe1B3, b spectrin, B-spec, beta-spectrin" "IPR018159:Spectrin/alpha-actinin, IPR011993:PH domain-like, IPR002017:Spectrin repeat, IPR001849:Pleckstrin homology domain, IPR001715:Calponin homology domain, IPR001605:Pleckstrin homology domain, spectrin-type, IPR001589:Actinin-type actin-binding domain, conserved site, IPR016343:Spectrin, beta subunit" CG5870 11-Aug-17 DroID_v2017_08 "Drer\LOC558044, Drer\actn2b, Drer\spna2, Drer\clmn, Drer\ehbp1, Drer\actn3a, Drer\zgc:100997, Drer\actn3b, Drer\ehbp1l1b, Drer\sptbn5, Drer\zgc:165653, Drer\actn4, Drer\sptb, Drer\sptbn1, Drer\si:dkey-27p18.5" - "Cele\unc-70, Cele\spc-1, Cele\sma-1" "Xtro\actn3, Xtro\ehbp1l1, Xtro\actn1, Xtro\sptbn2, Xtro\actn2, Xtro\sptbn5, Xtro\sptan1, Xtro\actn4, Xtro\ehbp1, Xtro\sptbn4" "Mmus\Actn2, Mmus\Actn1, Mmus\Sptan1, Mmus\Sptbn4, Mmus\Clmn, Mmus\Sptbn2, Mmus\Ehbp1, Mmus\Actn3, Mmus\Sptbn1, Mmus\Sptb, Mmus\Spta1, Mmus\Ehbp1l1, Mmus\Actn4" "Hsap\SPTBN5, Hsap\SPTB, Hsap\EHBP1, Hsap\CLMN, Hsap\SPTBN2, Hsap\SPTBN4, Hsap\SPTAN1, Hsap\SPTBN1, Hsap\ACTN1, Hsap\ACTN2, Hsap\ACTN4, Hsap\EHBP1L1, Hsap\SPTA1" " embryonic stage , embryonic stage | stage 10 " " larval visceral muscle

, embryonic/larval trachea

, mesoderm

, epidermis

, inclusive hindgut primordium

, embryonic/larval foregut | precursor

, embryonic/larval somatic muscle

" " embryonic stage | early , adult stage && oogenesis stage , embryonic stage | mid & late , embryonic stage | mid , embryonic stage | mid-late , adult stage && oogenesis stage | early , embryonic stage | late " " amnioproctodeal invagination

, follicle cell

, ventral furrow

, embryonic/larval somatic muscle

, ventral midline

, embryonic/larval hindgut

, embryonic/larval trachea

, spectrosome &&of germarium

, epidermis

, larval visceral muscle

, fusome &&of germarium

, pharyngeal muscle

, cephalic furrow

, embryonic/larval salivary gland

, embryonic/larval esophagus

, amnioserosa

" FBgn0053892 His2B:CG33892 His2B:CG33892 http://flybase.org/reports/FBgn0053892 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33892, His2B:CG33892, His2b:CG33892" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33892 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-261m9.6, Drer\si:ch1073-159d7.5, Drer\zgc:173585, Drer\zgc:194989, Drer\si:ch211-113a14.28, Drer\si:dkey-108k21.11, Drer\si:dkey-23a13.5, Drer\zgc:173587, Drer\si:ch211-113a14.11, Drer\hist2h2l, Drer\zgc:92591, Drer\si:dkey-23a13.1, Drer\si:ch211-113a14.29, Drer\ano9a, Drer\si:ch73-36p18.3, Drer\LOC100329290, Drer\LOC100334869, Drer\si:ch73-368j24.8, Drer\hist1h2ba, Drer\LOC100329560, Drer\si:ch1073-159d7.13, Drer\LOC100334559, Drer\si:ch1073-153i20.3, Drer\zgc:114046, Drer\si:dkey-23a13.16, Drer\si:dkey-108k21.27, Drer\si:dkey-261m9.19" "Scer\HTB2, Scer\HTB1" "Cele\his-22, Cele\his-4, Cele\his-11, Cele\his-52, Cele\his-29, Cele\his-66, Cele\his-62, Cele\his-34, Cele\his-58, Cele\his-20, Cele\his-48, Cele\his-44, Cele\his-39, Cele\his-41, Cele\his-54, Cele\his-8, Cele\his-15" "Xtro\LOC100495578, Xtro\LOC101733828, Xtro\LOC101735218, Xtro\LOC100492632, Xtro\LOC100485294, Xtro\hist1h2bj, Xtro\LOC100497915, Xtro\LOC100498553, Xtro\LOC101733489, Xtro\LOC101731852, Xtro\LOC100496445, Xtro\LOC100498647, Xtro\LOC100496436, Xtro\LOC100497082, Xtro\LOC101734862, Xtro\LOC100486870, Xtro\LOC100495396, Xtro\LOC100487485, Xtro\LOC100498072, Xtro\LOC101734494, Xtro\LOC101735164, Xtro\LOC101731067, Xtro\LOC100485134, Xtro\LOC101730940, Xtro\hist1h2bm, Xtro\LOC100495415, Xtro\LOC100498329, Xtro\LOC101733171, Xtro\LOC100486150, Xtro\LOC101731959, Xtro\LOC100496181, Xtro\hist1h2bk, Xtro\LOC100495041, Xtro\hist2h2be" "Mmus\Hist1h2ba, Mmus\Hist1h2bj, Mmus\Hist1h2be, Mmus\Hist1h2bf, Mmus\Hist1h2bk, Mmus\Hist1h2bm, Mmus\Hist1h2bc, Mmus\Hist1h2br, Mmus\Hist2h2be, Mmus\Hist1h2bq, Mmus\1700024P04Rik, Mmus\Hist1h2bg, Mmus\Hist1h2bb, Mmus\H2bfm, Mmus\Hist1h2bl, Mmus\Hist2h2bb, Mmus\Hist1h2bh, Mmus\Hist1h2bp, Mmus\Hist1h2bn, Mmus\Hist3h2ba" "Hsap\HIST1H2BB, Hsap\HIST1H2BK, Hsap\HIST1H2BL, Hsap\HIST1H2BE, Hsap\HIST3H2BB, Hsap\HIST1H2BD, Hsap\H2BFWT, Hsap\HIST1H2BH, Hsap\HIST1H2BJ, Hsap\HIST1H2BO, Hsap\HIST1H2BN, Hsap\HIST1H2BI, Hsap\HIST2H2BF, Hsap\HIST1H2BM, Hsap\HIST2H2BE, Hsap\HIST1H2BF, Hsap\HIST1H2BA, Hsap\HIST1H2BG, Hsap\H2BFM, Hsap\HIST1H2BC" FBgn0020865 cass cassowary http://flybase.org/reports/FBgn0020865 - gene molecular_function ; GO:0003674 | no biological data available apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "bad, cas, cass" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,somatic clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" "wing,somatic clone,embryonic/first instar larval cuticle,dorsal,embryonic/larval somatic muscle" FBgn0028315 l(1)G0356 lethal (1) G0356 http://flybase.org/reports/FBgn0028315 gene - - - l(1)G0356 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" adult abdomen FBgn0264664 steeple steeple http://flybase.org/reports/FBgn0264664 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - steeple - - 11-Aug-17 DroID_v2017_08 - - - - - - "embryonic/larval dorsal trunk,embryonic/larval tracheal system,eye,somatic clone" FBgn0034744 Vps20 Vacuolar protein sorting 20 http://flybase.org/reports/FBgn0034744 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vacuolar transport ; GO:0007034 | inferred from electronic annotation with InterPro:IPR005024 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype negative regulation of epithelial cell proliferation ; GO:0050680 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype ESCRT III complex ; GO:0000815 | inferred from sequence or structural similarity with SGD:S000004682 "vps20, CG4071, anon-EST:Posey40, Vps20, ESCRT-III, DmVPS20" IPR005024:Snf7 family CG4071 11-Aug-17 DroID_v2017_08 "Drer\chmp6b, Drer\chmp6a" "Scer\VPS20, Scer\CHM7" Cele\vps-20 Xtro\chmp6 Mmus\Chmp6 Hsap\CHMP6 "increased cell number,lethal,partially lethal - majority die,visible" "eye,somatic clone,epithelium,interfollicle cell,female germline cyst,trichogen cell,mesothoracic tergum" FBgn0036007 path pathetic http://flybase.org/reports/FBgn0036007 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transporter activity ; GO:0015171 | inferred from direct assay amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 growth ; GO:0040007 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype amino acid transmembrane transport ; GO:0003333 | inferred from direct assay regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype regulation of cell projection size ; GO:0032536 | inferred from mutant phenotype amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 dendrite extension ; GO:0097484 | inferred from mutant phenotype amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 endolysosome ; GO:0036019 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN001119389 "path, CG3424, anon-WO0118547.370, anon-WO0118547.271, pth, Path" "IPR013057:Amino acid transporter, transmembrane domain" CG3424 11-Aug-17 DroID_v2017_08 "Drer\slc36a1, Drer\slc36a4" "Scer\AVT4, Scer\AVT3" "Cele\slc-36.3, Cele\Y43F4B.7, Cele\slc-36.2, Cele\skat-1, Cele\slc-36.5, Cele\slc-36.4" "Xtro\slc36a1, Xtro\slc36a4" "Mmus\Slc36a2, Mmus\Slc36a1, Mmus\Slc36a4, Mmus\Slc36a3, Mmus\Slc38a10" "Hsap\SLC36A1, Hsap\SLC36A3, Hsap\SLC36A4, Hsap\SLC38A10, Hsap\SLC36A2" "small body,decreased cell number,decreased cell size,developmental rate defective,eclosion rhythm defective,female sterile,increased cell size,increased cell number,viable,size defective" "wing,ommatidium,adult salivary gland,adult fat body,eye,posterior" FBgn0061001 l(3)S026821 lethal (3) S026821 http://flybase.org/reports/FBgn0061001 gene - - - "0268/21, l(3)S026821" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0016078 wun wunen http://flybase.org/reports/FBgn0016078 FBgn0017369 protein_coding_gene phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000017950 protein homodimerization activity ; GO:0042803 | traceable author statement phosphatidate phosphatase activity ; GO:0008195 | non-traceable author statement lipid phosphatase activity ; GO:0042577 | inferred from biological aspect of ancestor with PANTHER:PTN000807400 phosphatase activity ; GO:0016791 | inferred from direct assay phospholipid dephosphorylation ; GO:0046839 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 germ cell repulsion ; GO:0035233 | traceable author statement embryonic pattern specification ; GO:0009880 | traceable author statement germ cell repulsion ; GO:0035233 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype ectopic germ cell programmed cell death ; GO:0035234 | traceable author statement dephosphorylation ; GO:0016311 | non-traceable author statement septate junction assembly ; GO:0019991 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype pole cell migration ; GO:0007280 | traceable author statement germ cell migration ; GO:0008354 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from expression pattern germ cell migration ; GO:0008354 | traceable author statement germ cell repulsion ; GO:0035233 | inferred from genetic interaction with wun2 phospholipid metabolic process ; GO:0006644 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype septate junction ; GO:0005918 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 apical part of cell ; GO:0045177 | inferred from direct assay "CG8804, Wunen, l(2)k16806, wun, Wun, LPP-like" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG8804 11-Aug-17 DroID_v2017_08 "Drer\ppap2d, Drer\LOC571722, Drer\plppr3b, Drer\plppr5a, Drer\plpp1a, Drer\plppr3a, Drer\plppr2a, Drer\plpp4, Drer\plpp5, Drer\plppr1, Drer\plppr4a, Drer\plppr2b, Drer\plpp3, Drer\plpp2b, Drer\plppr5b, Drer\LOC794598, Drer\plpp2a" "Scer\DPP1, Scer\LPP1" "Cele\T28D9.3, Cele\T06D8.3, Cele\F53C3.13, Cele\F13E6.5" "Xtro\plpp3, Xtro\plpp4, Xtro\LOC100135382, Xtro\plpp5, Xtro\plpp1, Xtro\plpp2" "Mmus\Plpp4, Mmus\Plpp2, Mmus\Plppr5, Mmus\Plppr4, Mmus\Plppr2, Mmus\Plppr1, Mmus\Plpp5, Mmus\Plpp3, Mmus\Plppr3, Mmus\Plpp1" "Hsap\PLPP2, Hsap\PLPP3, Hsap\PLPPR3, Hsap\PLPPR4, Hsap\PLPPR5, Hsap\PLPP5, Hsap\PLPP1, Hsap\PLPP4, Hsap\PLPPR1, Hsap\PLPPR2" " embryonic stage | late , embryonic stage " " embryonic central nervous system

, ectoderm | restricted

, posterior midgut proper primordium | dorsal

, inclusive hindgut primordium

" "learning defective,viable,fertile,lethal,recessive,neuroanatomy defective,wild-type,female sterile,partially lethal - majority die" "embryonic/larval dorsal trunk,embryonic/larval lateral trunk,embryonic/larval transverse connective,germline cell,female,male,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,embryonic proventriculus,presumptive embryonic/larval digestive system,synapse,bouton" FBgn0001959 l(2)34Db lethal (2) 34Db http://flybase.org/reports/FBgn0001959 - gene - - - "l(2)br20, l34Db, 34Db, br20, l(2)br21, l(2)br18, l(2)06311, l(2)34Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,female sterile,male sterile,visible" "eye,ocellar bristle,posterior scutellar bristle,macrochaeta,wing" FBgn0003882 tub tube http://flybase.org/reports/FBgn0003882 "FBan0010520, FBgn0015226" protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from physical interaction with UniProtKB:Q05652 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q05652 Toll signaling pathway ; GO:0008063 | traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 determination of dorsal/ventral asymmetry ; GO:0048262 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | non-traceable author statement hemocyte proliferation ; GO:0035172 | traceable author statement larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype hemopoiesis ; GO:0030097 | traceable author statement Toll signaling pathway ; GO:0008063 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | traceable author statement antifungal humoral response ; GO:0019732 | inferred from mutant phenotype defense response ; GO:0006952 | traceable author statement Toll signaling pathway ; GO:0008063 | non-traceable author statement response to fungus ; GO:0009620 | traceable author statement innate immune response ; GO:0045087 | traceable author statement apoptotic process ; GO:0006915 | non-traceable author statement cytoplasm ; GO:0005737 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000784925 cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG10520, tub, Tube" "IPR000488:Death domain, IPR011029:Death-like domain, IPR029397:Tube Death domain" CG10520 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-26a9.2 "Scer\ALK2, Scer\ALK1" "Cele\C50H2.7, Cele\F59E12.15, Cele\Y73B6A.1, Cele\hasp-1, Cele\hasp-2, Cele\C06E4.5, Cele\C55C3.8, Cele\C04G2.10, Cele\VY10G11R.1, Cele\ZK177.2, Cele\C26E6.1" - Mmus\Gsg2 Hsap\GSG2 " embryonic stage -- adult stage , adult stage && oogenesis stage " oocyte

"viable,fertile,lethal,maternal effect,dorsal/ventral axis specification defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,wild-type,cold sensitive,heat sensitive" "embryonic/first instar larval cuticle,hemocyte,embryonic/larval hemolymph,embryonic/larval hemocyte,embryonic/larval somatic muscle,segment border muscle,epidermis" DRSC22800 EK -1.214803202 0.694340053 -1.777558022 1.236314012 1.876121648 -0.064118413 FBgn0031759 lid little imaginal discs http://flybase.org/reports/FBgn0031759 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001606 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors ; GO:0016706 | inferred from electronic annotation with InterPro:IPR013637 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 histone acetyltransferase activity (H3-K9 specific) ; GO:0043992 | contributes_to inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with Myc histone demethylase activity (H3-K4 specific) ; GO:0032453 | inferred from mutant phenotype histone demethylase activity (H3-trimethyl-K4 specific) ; GO:0034647 | inferred from mutant phenotype" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR013637 karyosome formation ; GO:0030717 | inferred from mutant phenotype histone H3-K4 demethylation, trimethyl-H3-K4-specific ; GO:0034721 | inferred from mutant phenotype circadian regulation of gene expression ; GO:0032922 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype synaptonemal complex organization ; GO:0070193 | inferred from mutant phenotype histone H3-K9 acetylation ; GO:0043970 | inferred from mutant phenotype histone H3-K4 demethylation ; GO:0034720 | inferred from mutant phenotype histone demethylation ; GO:0016577 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype negative regulation of stem cell differentiation ; GO:2000737 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay Sin3-type complex ; GO:0070822 | inferred from direct assay "LID, lid, dKDM5, CG9088, l(2)10424, Lid, dJARID1, KDM5, Kdm5, dKDM5/LID" "IPR001606:ARID DNA-binding domain, IPR001965:Zinc finger, PHD-type, IPR003347:JmjC domain, IPR003349:JmjN domain, IPR004198:Zinc finger, C5HC2-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR013637:Lysine-specific demethylase-like domain, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9088 11-Aug-17 DroID_v2017_08 "Drer\kdm6a, Drer\kdm5ba, Drer\kdm5bb, Drer\kdm5c, Drer\kdm5a, Drer\jarid2b, Drer\kdm6al" "Scer\ECM5, Scer\JHD2" Cele\rbr-2 "Xtro\kdm5b, Xtro\kdm6a, Xtro\kdm5a, Xtro\kdm6b, Xtro\kdm5c, Xtro\tmem30c" "Mmus\Kdm5b, Mmus\Kdm5d, Mmus\Kdm5a, Mmus\Uty, Mmus\Kdm5c, Mmus\Kdm6b, Mmus\Kdm6a" "Hsap\KDM6A, Hsap\KDM5D, Hsap\KDM5B, Hsap\KDM5C, Hsap\UTY, Hsap\KDM5A, Hsap\KDM6B" "viable,female sterile,short lived,male,chemical sensitive,lethal,partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,dominant,locomotor rhythm defective,visible" "imaginal disc,embryonic/larval optic lobe,macrochaeta,supernumerary,mesothoracic tergum" FBgn0263979 Caf1-55 "Chromatin assembly factor 1, p55 subunit" http://flybase.org/reports/FBgn0263979 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Caf1-55 histone binding ; GO:0042393 | traceable author statement histone methyltransferase activity ; GO:0042054 | contributes_to inferred from direct assay histone acetyltransferase binding ; GO:0035035 | inferred from sequence or structural similarity with SGD:S000000782 nucleosome-dependent ATPase activity ; GO:0070615 | contributes_to inferred by curator from GO:0016589 histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | contributes_to inferred by curator from GO:0035098 protein binding ; GO:0005515 | inferred from physical interaction with MBD-like histone binding ; GO:0042393 | inferred from direct assay nucleosome binding ; GO:0031491 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V464 histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with HGNC:9887 inferred from direct assay histone methyltransferase activity (H3-K27 specific) ; GO:0046976 | contributes_to inferred by curator from GO:0035098 "muscle organ development ; GO:0007517 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from sequence or structural similarity with SGD:S000000782 inferred from direct assay nucleosome mobilization ; GO:0042766 | inferred from direct assay histone methylation ; GO:0016571 | inferred from direct assay regulation of histone H3-K27 methylation ; GO:0061085 | NOT inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype DNA repair ; GO:0006281 | traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from physical interaction with esc inferred from physical interaction with E(z) nucleosome positioning ; GO:0016584 | inferred from direct assay neuron development ; GO:0048666 | inferred from mutant phenotype nucleosome assembly ; GO:0006334 | inferred from direct assay transcription, DNA-templated ; GO:0006351 | inferred from direct assay chromatin assembly ; GO:0031497 | inferred from direct assay chromatin assembly ; GO:0031497 | inferred from sequence or structural similarity with HGNC:9887 inferred from sequence or structural similarity with HGNC:9890 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | inferred by curator from GO:0031523" Myb complex ; GO:0031523 | inferred from direct assay NuRD complex ; GO:0016581 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay ACF complex ; GO:0016590 | NOT inferred from direct assay NURF complex ; GO:0016589 | traceable author statement histone methyltransferase complex ; GO:0035097 | inferred from direct assay CAF-1 complex ; GO:0033186 | inferred from direct assay ESC/E(Z) complex ; GO:0035098 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with Trf2 NURF complex ; GO:0016589 | inferred from physical interaction with Iswi NURF complex ; GO:0016589 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay Sin3-type complex ; GO:0070822 | inferred from direct assay "p55, NURF55, Nurf55, CG4236, CAF1, Nurf 55, p55 CAF1, CAF1-55, Nurf, NURF-55, RbAp48, CAF-1, p55CAF1, CAF1p55, Nurf-55, caf1, Caf-1, NURF, P55, dCAF-1, d-CAF1, dCAF-1 p55, dNURF, Caf1/p55, p55/NURF-55, 55, caf1 p55, Caf1p55, p55,CAF1, MSI1/RbAp48/CAC3/LIN-53, caf-1, 154659_at, S(ls)3, NURF 55, Caf1, dCAF1, CAF1-p55, dCAF1-p55, dCAF-1-p55, RbAp46/48, Caf1-55, RBAP48, Caf1 (p55)" "IPR022052:Histone-binding protein RBBP4, N-terminal, IPR020472:G-protein beta WD-40 repeat, IPR019775:WD40 repeat, conserved site, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG4236 11-Aug-17 DroID_v2017_08 "Drer\rbbp4, Drer\rbb4l" "Scer\MSI1, Scer\HAT2" "Cele\rba-1, Cele\lin-53" "Xtro\wdr59, Xtro\rbbp7, Xtro\rbbp4" "Mmus\Rbbp7, Mmus\Wdr73, Mmus\Rbbp4" "Hsap\WDR59, Hsap\WDR73, Hsap\RBBP7, Hsap\RBBP4" embryonic stage--larval stage DRSC16596 I -2.289954258 -2.716505732 -0.339223968 -0.625909046 0.093045386 0.100834671 FBgn0002566 lt light http://flybase.org/reports/FBgn0002566 "FBan0018028, FBgn0032992" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model GTPase binding ; GO:0051020 | inferred from biological aspect of ancestor with PANTHER:PTN000289375 "protein targeting to vacuole ; GO:0006623 | inferred from biological aspect of ancestor with PANTHER:PTN000289375 autophagosome maturation ; GO:0097352 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype lysosomal transport ; GO:0007041 | traceable author statement ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype intracellular transport ; GO:0046907 | traceable author statement negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype vacuole fusion, non-autophagic ; GO:0042144 | inferred from biological aspect of ancestor with PANTHER:PTN000289375 regulation of SNARE complex assembly ; GO:0035542 | inferred from biological aspect of ancestor with PANTHER:PTN000289375 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with SGD:S000002487 regulation of SNARE complex assembly ; GO:0035542 | inferred from sequence or structural similarity with SGD:S000002487 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" CORVET complex ; GO:0033263 | inferred from biological aspect of ancestor with PANTHER:PTN000289375 HOPS complex ; GO:0030897 | inferred from mutant phenotype HOPS complex ; GO:0030897 | inferred from sequence or structural similarity with SGD:S000002487 late endosome ; GO:0005770 | inferred from biological aspect of ancestor with PANTHER:PTN000289375 "lt, Dm-lt(het), l(2)40Fb, CG18028, Lt, Vps41, vps41" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR000547:Clathrin, heavy chain/VPS, 7-fold repeat, IPR001680:WD40 repeat, IPR001841:Zinc finger, RING-type, IPR016902:Vacuolar protein sorting-associated protein 41, IPR016024:Armadillo-type fold, IPR011990:Tetratricopeptide-like helical domain" CG18028 11-Aug-17 DroID_v2017_08 Drer\vps41 "Scer\VPS8, Scer\VPS41" Cele\vps-41 Xtro\vps41 Mmus\Vps41 Hsap\VPS41 " larval stage , larval stage | third instar , egg stage | unfertilized egg , embryonic stage -- adult stage , embryonic stage , adult stage | female " " embryonic/larval fat body

, larval brain

, unfertilized egg | ubiquitous

, Malpighian tubule

, larval digestive system

, embryonic/larval circulatory system

, unfertilized egg

,

ubiquitous , imaginal disc

, gonad

, ovary

, larval salivary gland

" "wild-type,short lived,male,eye color defective,lethal,partially,recessive,viable,dominant,lethal - all die before end of pupal stage,some die during pupal stage,visible,enhancer of variegation,suppressor of variegation,sterile" "ocellus pigment granule,pigment cell,embryonic/larval fat body,nutrition conditional,autolysosome | wandering third instar larval stage | nutrition conditionallt45),autophagic vacuole | supernumerary | wandering third instar larval stage | nutrition conditionallt45),Malpighian tubule,wing,eye,somatic clone,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0030985 Obp18a Odorant-binding protein 18a http://flybase.org/reports/FBgn0030985 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "18a, CG15883, BcDNA:RH25665, Obp18a, DmelObp18a, obp18a" IPR006170:Pheromone/general odorant binding protein CG15883 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0027283 l(1)G0179 lethal (1) G0179 http://flybase.org/reports/FBgn0027283 - gene - - - l(1)G0179 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0020626 Osbp Oxysterol binding protein http://flybase.org/reports/FBgn0020626 - protein_coding_gene - sperm individualization ; GO:0007291 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "OSBP-Dm, CG6708, Osbp, osbp, OSBP" "IPR018494:Oxysterol-binding protein, conserved site, IPR000648:Oxysterol-binding protein, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG6708 11-Aug-17 DroID_v2017_08 "Drer\osbpl6, Drer\si:ch211-106a19.1, Drer\osbp2, Drer\osbpl3a, Drer\osbpl1a, Drer\osbpl2b, Drer\osbp, Drer\osbpl2a, Drer\LOC100331149, Drer\osbpl3b, Drer\osbpl7" "Scer\OSH2, Scer\OSH7, Scer\OSH3, Scer\SWH1" "Cele\obr-2, Cele\obr-1" "Xtro\osbp, Xtro\osbpl3, Xtro\osbpl1a, Xtro\osbpl2, Xtro\osbp2" "Mmus\Osbpl2, Mmus\Osbpl6, Mmus\Osbp, Mmus\Osbpl3, Mmus\Osbpl7, Mmus\Osbpl1a, Mmus\Osbp2" "Hsap\OSBPL3, Hsap\OSBPL7, Hsap\OSBP, Hsap\OSBP2, Hsap\OSBPL6, Hsap\OSBPL2, Hsap\OSBPL1A" "visible,viable,male semi-sterile,male sterile" "wing,adult thorax,adult cuticle,Golgi apparatusCCAP.PP,individualization stage spermatid" FBgn0264654 missing-parts missing parts http://flybase.org/reports/FBgn0264654 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - missing-parts - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "embryonic/larval dorsal trunk,terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0037379 CG10979 - http://flybase.org/reports/FBgn0037379 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG10979 IPR013087:Zinc finger C2H2-type CG10979 11-Aug-17 DroID_v2017_08 "Drer\znf800b, Drer\znf800a" - "Cele\die-1, Cele\T08G5.7, Cele\F58D12.5" Xtro\znf800 "Mmus\Zfy1, Mmus\Zfy2, Mmus\Zfp800" Hsap\ZNF800 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,supernumerary,mesothoracic tergum" FBgn0028513 CG9254 - http://flybase.org/reports/FBgn0028513 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 sodium:phosphate symporter activity ; GO:0005436 | inferred from sequence or structural similarity transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "DS07660.1, BG:DS07660.1, CG9254" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG9254 11-Aug-17 DroID_v2017_08 "Drer\slc17a8, Drer\slc17a5, Drer\si:ch1073-513e17.1, Drer\slc17a7a, Drer\slc17a9a, Drer\ppt1, Drer\slc17a6b, Drer\slc17a6a" "Scer\FEN2, Scer\THI73, Scer\TNA1, Scer\YIL166C, Scer\DAL5" "Cele\vglu-2, Cele\Y19D10A.8, Cele\slc-17.1, Cele\T11G6.4, Cele\slc-17.2, Cele\slc-17.6, Cele\eat-4, Cele\vglu-3, Cele\slc-17.7" Xtro\slc17a7 "Mmus\Slc37a2, Mmus\Slc17a6, Mmus\Slc17a3, Mmus\Slc17a1, Mmus\Slc17a5, Mmus\Slc17a8, Mmus\Slc17a7, Mmus\Slc17a4, Mmus\Slc17a2" "Hsap\SLC17A7, Hsap\SLC17A2, Hsap\SLC17A5, Hsap\SLC17A6, Hsap\SLC17A1, Hsap\SLC37A2, Hsap\SLC17A8, Hsap\SLC17A3, Hsap\SLC17A4" viable FBgn0031260 Spp Signal peptide peptidase http://flybase.org/reports/FBgn0031260 protein_coding_gene "aspartic endopeptidase activity, intramembrane cleaving ; GO:0042500 | inferred from direct assay" signal peptide processing ; GO:0006465 | inferred from direct assay cellular response to unfolded protein ; GO:0034620 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay integral component of lumenal side of endoplasmic reticulum membrane ; GO:0071556 | inferred from biological aspect of ancestor with PANTHER:PTN000256093 Golgi-associated vesicle membrane ; GO:0030660 | inferred from biological aspect of ancestor with PANTHER:PTN000256093 membrane ; GO:0016020 | inferred from direct assay integral component of cytoplasmic side of endoplasmic reticulum membrane ; GO:0071458 | inferred from biological aspect of ancestor with PANTHER:PTN000256093 lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN000256093 "spp, CG11840, Spp, SPP, DmSPP" "IPR006639:Presenilin/signal peptide peptidase, IPR007369:Peptidase A22B, signal peptide peptidase" CG11840 11-Aug-17 DroID_v2017_08 "Drer\sppl2, Drer\sppl3, Drer\hm13" Scer\YPF1 "Cele\imp-3, Cele\imp-1, Cele\imp-2" "Xtro\sppl2a, Xtro\sppl3, Xtro\hm13" "Mmus\Sppl2a, Mmus\Sppl2b, Mmus\Sppl3, Mmus\H13" "Hsap\SPPL2C, Hsap\SPPL3, Hsap\HM13" "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,visible,viable" "heart primordium,embryonic/larval tracheal system,wing,posterior compartment,trichogen cell" FBgn0040158 l(1)G0451 lethal (1) G0451 http://flybase.org/reports/FBgn0040158 gene - - - l(1)G0451 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263885 l(3)B27 - http://flybase.org/reports/FBgn0263885 gene - - - l(3)B27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0032196 CG5708 - http://flybase.org/reports/FBgn0032196 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 - - CG5708 "IPR001781:Zinc finger, LIM-type" CG5708 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-90l8.3, Drer\lmo4a, Drer\lmo1, Drer\lmo3, Drer\zgc:56628, Drer\lmo2, Drer\lmo4b" Scer\RGA2 Cele\lin-11 "Xtro\lmo2, Xtro\lmo4.1, Xtro\lmo4.2" "Mmus\Lmo1, Mmus\Lmo2, Mmus\Lmo3, Mmus\Lmo4" "Hsap\LMO3, Hsap\LMO2, Hsap\LMO1, Hsap\LMO4" viable FBgn0004859 ci cubitus interruptus http://flybase.org/reports/FBgn0004859 "FBgn0000314, FBgn0000315, FBgn0010154, FBgn0010155, FBgn0017411, FBgn0019831" protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from genetic interaction with nej protein binding ; GO:0005515 | inferred from physical interaction with nej protein binding ; GO:0005515 | inferred from physical interaction with hyx RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with slmb transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Rbfox1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VFP2 protein homodimerization activity ; GO:0042803 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0001205 | inferred from mutant phenotype DNA binding ; GO:0003677 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with rdx" "positive regulation of epithelial cell differentiation ; GO:0030858 | inferred from mutant phenotype mucosal immune response ; GO:0002385 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype inferred from genetic interaction with nej oogenesis ; GO:0048477 | inferred from expression pattern positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement segment polarity determination ; GO:0007367 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype labial disc development ; GO:0035217 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | traceable author statement positive regulation of G1/S transition of mitotic cell cycle ; GO:1900087 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement smoothened signaling pathway ; GO:0007224 | inferred from expression pattern smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | non-traceable author statement smoothened signaling pathway ; GO:0007224 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement heart formation ; GO:0060914 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern eye morphogenesis ; GO:0048592 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay epidermis development ; GO:0008544 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement" protein complex ; GO:0043234 | inferred from physical interaction with Su(fu) cytoplasm ; GO:0005737 | inferred from direct assay Hedgehog signaling complex ; GO:0035301 | inferred from physical interaction with cos inferred from physical interaction with fu nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement membrane ; GO:0016020 | inferred from direct assay "Ci, ci, Gli, CI, CG2125, ci155, CID, CiD, ciD, l(4)17, ci[D], ci-D, Ci[D], Ce, l(4)13, l(4)102ABc, Ci/GLI, Siah, Ci/Gli, Ci155" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2125 11-Aug-17 DroID_v2017_08 "Drer\gli2b, Drer\gli1, Drer\gli3, Drer\glis3, Drer\gli2a" "Scer\MIG2, Scer\AZF1" "Cele\ztf-14, Cele\tra-1, Cele\klu-1" "Xtro\gli3, Xtro\gli2, Xtro\gli1" "Mmus\Gli2, Mmus\Gli3, Mmus\Glis3, Mmus\Zp2, Mmus\Gli1" "Hsap\GLI1, Hsap\GLIS3, Hsap\GLI3, Hsap\ZP2, Hsap\GLIS1, Hsap\GLI2" " embryonic stage , embryonic stage | cellular blastoderm , embryonic stage | gastrula , embryonic stage | stage 7 , larval stage , embryonic stage | extended germ band " " mesectoderm

, embryonic central nervous system

,

ubiquitous ,

, embryonic/larval hindgut

, segment

, ectoderm

,

segment polarity , imaginal disc | anterior

, embryonic/larval foregut

, ectoderm | striped

, mesoderm

" larval stage | third instar " dorsal mesothoracic disc | anterior compartment & proximal to anterior/posterior compartment boundary

, male genital disc | restricted

, female genital disc | restricted

" "visible,neuroanatomy defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,cold sensitive,lethal - all die before end of pupal stage,some die during pupal stage,viable,somatic clone,mitotic cell cycle defective,cell autonomous,sterile,wild-type,segment polarity phenotype,partially,homeotic" "eye,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,dorsal multidendritic neuron ddaD,wing vein,embryonic epidermis,wing vein L4,wing vein L5,embryonic/first instar larval cuticle,leg,wing,ommatidial precursor cluster,anterior compartment,ventral thoracic disc,wing disc,antenna,ommatidium,somatic clone,wing blade,wing vein L2,wing vein L3,ectopic,wing vein L4 & sensillum campaniformium | ectopic | somatic clone,wing vein L4 & wing sensillum | ectopic | somatic clone,denticle belt,denticle,denticle row 2,denticle row 3,denticle row 4,follicle stem cell,anterior,ventral,denticle row 1,supernumerary,eye disc,cell autonomous,prothoracic ventral denticle belt,ocellus,ocellar bristle,scutellar bristle,postvertical bristle,Bolwig organ,denticle row 5,denticle row 6,embryo,posterior compartment,embryonic/larval dorsal vessel,mesothoracic tarsal bristle longitudinal row 1,wing margin bristle,alula,wing margin,posterior,keyhole structure,trichome of the posterior wing margin,cold sensitive,interfollicle cell,interommatidial bristle,retina,lamina,lamina & neuron | precursor‘±Tub84B.PP,1st posterior cell,thorax,head capsule,dorsal,embryonic/larval dorsal branch,egg chamber,germarium,morphogenetic furrow,tracheal tip cell | embryonic stage,filzkorper,stigmatophore,larval thoracic segment,larval abdominal segment,pseudotrachea,anal plate,adult hindgut,proximal,S phase | ectopic | somatic clone,S phase | ectopicbbg-C96,sensory mother cell,anterior crossvein,distal,glial cell & eye disc | somatic clone,dorsal branch primordium" FBgn0040290 RecQ4 RecQ4 helicase http://flybase.org/reports/FBgn0040290 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 four-way junction helicase activity ; GO:0009378 | inferred from biological aspect of ancestor with PANTHER:PTN000344873 single-stranded DNA binding ; GO:0003697 | inferred from direct assay DNA helicase activity ; GO:0003678 | inferred from sequence or structural similarity with UniProtKB:P15043 helicase activity ; GO:0004386 | inferred from sequence or structural similarity DNA-dependent ATPase activity ; GO:0008094 | inferred from direct assay ATP-dependent 3'-5' DNA helicase activity ; GO:0043140 | inferred from direct assay DNA-dependent ATPase activity ; GO:0008094 | inferred from sequence or structural similarity with HGNC:9949 DNA duplex unwinding ; GO:0032508 | inferred from direct assay DNA replication ; GO:0006260 | inferred from sequence or structural similarity with HGNC:9949 DNA replication ; GO:0006260 | inferred from mutant phenotype base-excision repair ; GO:0006284 | inferred from mutant phenotype larval development ; GO:0002164 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from sequence or structural similarity with HGNC:9949 cell division ; GO:0051301 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype double-strand break repair ; GO:0006302 | inferred from mutant phenotype positive regulation of G2/M transition of mitotic cell cycle ; GO:0010971 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype inferred from genetic interaction with nbs DNA rewinding ; GO:0036292 | inferred from direct assay positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from biological aspect of ancestor with PANTHER:PTN000344874 positive regulation of DNA replication ; GO:0045740 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay chromatin ; GO:0000785 | colocalizes_with inferred from direct assay "cg7487, DmRECQ4, CG7487, RecQ4, dRecQ4, RECQL4" "IPR001650:Helicase, C-terminal, IPR001878:Zinc finger, CCHC-type, IPR004589:DNA helicase, ATP-dependent, RecQ type, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR021110:DNA replication/checkpoint protein" CG7487 11-Aug-17 DroID_v2017_08 "Drer\blm, Drer\recql, Drer\wrn, Drer\recql4" Scer\SGS1 Cele\wrn-1 "Xtro\wrn, Xtro\recql, Xtro\recql4, Xtro\blm" "Mmus\Blm, Mmus\Wrn, Mmus\Recql4, Mmus\Recql" "Hsap\RECQL4, Hsap\RECQL, Hsap\BLM, Hsap\WRN" "female sterile,partially lethal - majority live,cell cycle defective,radiation sensitive,developmental rate defective,recessive,germline clone,decreased cell size,endomitotic cell cycle defective,mitotic cell cycle defective,DNA repair defective,chemical sensitive,decreased cell number,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,viable,lethal,lethal - all die before end of larval stage,some die during larval stage" "egg,spiracle,oocyte,germline clone,cell & larval brain,cell & larval salivary gland,chromosome,cell & dorsal mesothoracic disc,eye,somatic clone,ommatidium,chorion,salivary gland,fat body,salivary gland imaginal ring,embryonic/larval brain" DRSC11265 K -0.481176399 0.152407668 -0.69920523 -0.452088587 3.123122742 1.432279476 FBgn0011785 BRWD3 BRWD3 http://flybase.org/reports/FBgn0011785 "FBgn0011039, FBgn0039181, FBgn0040598, FBgn0051132, FBgn0061821, FBgn0061922" protein_coding_gene - regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000417686 ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from genetic interaction with upd1 negative regulation of chromatin binding ; GO:0035562 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000417686 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs cytoskeleton organization ; GO:0007010 | inferred from biological aspect of ancestor with PANTHER:PTN000417686 regulation of photoreceptor cell differentiation ; GO:0046532 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000417686 "brwd3, psg13, dBRWD3, CG31132, CG6400, CG18670, l(3)05842, anon-WO0118547.620, anon-WO0118547.520, l(3)s5349, BRWD3, ram, Brwd3" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001487:Bromodomain, IPR001680:WD40 repeat, IPR018359:Bromodomain, conserved site, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site" CG31132 11-Aug-17 DroID_v2017_08 "Drer\phip, Drer\brwd1, Drer\brwd3" - Cele\nurf-1 "Xtro\brwd3, Xtro\phip, Xtro\brwd1" "Mmus\Brwd3, Mmus\Brwd1, Mmus\Phip" "Hsap\PHIP, Hsap\BRWD3, Hsap\BRWD1" "lethal,recessive,partially lethal - majority die,visible,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval salivary gland,embryonic/larval midgut,eye,somatic clone,eye disc & nucleus | somatic clone,eye disc & actin cytoskeleton | somatic clone,rhabdomere & eye disc & pupa,wing vein,ectopic" DRSC15369 IEK -2.152006821 -1.467909399 -4.566517352 0.332917226 1.55042762 1.978675559 FBgn0021880 l(2)k13604 lethal (2) k13604 http://flybase.org/reports/FBgn0021880 - gene - - - l(2)k13604 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0034433 EndoB Endophilin B http://flybase.org/reports/FBgn0034433 protein_coding_gene lysophosphatidic acid acyltransferase activity ; GO:0042171 | inferred from sequence or structural similarity with EndoA phospholipid binding ; GO:0005543 | inferred from sequence or structural similarity with EndoA regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype vitellogenesis ; GO:0007296 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype membrane organization ; GO:0061024 | inferred from mutant phenotype membrane tubulation ; GO:0097320 | inferred from sequence or structural similarity with EndoA cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004148 membrane ; GO:0016020 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with EndoA "D-endoB, CG9834, endoB, EndoB, D-EndoB" "IPR001452:SH3 domain, IPR004148:BAR domain, IPR027267:Arfaptin homology (AH) domain/BAR domain" CG9834 11-Aug-17 DroID_v2017_08 "Drer\sh3glb1b, Drer\sh3glb2b, Drer\sh3glb2a, Drer\LOC101886286, Drer\sh3glb1a" - Cele\erp-1 "Xtro\sh3glb2, Xtro\sh3glb1" "Mmus\Sh3glb1, Mmus\Sh3glb2" "Hsap\SH3GLB2, Hsap\SH3GLB1" "lethal,recessive,female semi-sterile,partially lethal - majority die,visible" "yolk granule,oocyte,egg chamber,mesothoracic tergum,eye" FBgn0264404 FCG-G - http://flybase.org/reports/FBgn0264404 gene - - - FCG-G - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0060938 l(3)S040506 lethal (3) S040506 http://flybase.org/reports/FBgn0060938 gene - - - "0405/06, l(3)S040506" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0034998 CG13577 - http://flybase.org/reports/FBgn0034998 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG13577 - CG13577 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" FBgn0067357 l(3)8E276 lethal (3) 8E276 http://flybase.org/reports/FBgn0067357 gene - - - l(3)8E276 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0083187 M(smoDN)K Modifier of smoDN group K http://flybase.org/reports/FBgn0083187 gene - smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "Group K, M(smoDN)K" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell lethalcell lethal,somatic clone" FBgn0022084 l(2)k07502b lethal (2) k07502b http://flybase.org/reports/FBgn0022084 - gene - - - "l(2)k07502B, 75/2, l(2)k07502, l(2)k07502b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0013576 mtd mustard http://flybase.org/reports/FBgn0013576 "FBgn0027705, FBgn0037311, FBgn0040681, FBgn0052464" protein_coding_gene - activation of innate immune response ; GO:0002218 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of stem cell proliferation ; GO:2000648 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "anon-EST:Posey263, L82, CG10199, CG10196, CG32464, l(3)82Fd, L(3)82Fd, mtd, l(3)82FD" "IPR018392:LysM domain, IPR006571:TLDc domain" CG32464 11-Aug-17 DroID_v2017_08 "Drer\LOC569262, Drer\oxr1a, Drer\LOC792958, Drer\oxr1b, Drer\si:ch211-15d5.11" Scer\OXR1 Cele\lmd-3 "Xtro\ncoa7, Xtro\tldc2, Xtro\oxr1" "Mmus\Ncoa7, Mmus\Tldc2, Mmus\Oxr1" "Hsap\NCOA7, Hsap\OXR1, Hsap\TLDC2" "viable,fertile,oxidative stress response defective,stress response defective,lethal,recessive,eye color defective,some die during immature adult stage,visible,wild-type" "intestinal stem cell,pigment cell,trichogen cell,mesothoracic tergum" FBgn0024230 Hs2st Heparan sulfate 2-O-sulfotransferase http://flybase.org/reports/FBgn0024230 FBgn0032784 protein_coding_gene heparan sulfate 2-O-sulfotransferase activity ; GO:0004394 | inferred from direct assay signal transduction ; GO:0007165 | non-traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype inferred from genetic interaction with Hs6st "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR007734" "HS2ST, DmHs2st, dHS2ST, CG10234, Hs2st, dmHS-2OST, dmHs2st, Hs2st-2" "IPR007734:Heparan sulphate 2-O-sulfotransferase, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR005331:Sulfotransferase" CG10234 11-Aug-17 DroID_v2017_08 "Drer\ust, Drer\hs2st1b, Drer\hs2st1a" - Cele\hst-2 Xtro\hs2st1 "Mmus\Ust, Mmus\Hs2st1" "Hsap\HS2ST1, Hsap\UST" "increased mortality during development,viable,partially lethal - majority die" "interfollicle cell,ovariole,imaginal tracheoblast,dorsal branch,presumptive embryonic/larval tracheal system" DRSC03348 K -1.054025722 0.12617455 0.283607147 -0.221522725 1.6198076 0.141712734 FBgn0020653 Trxr-1 Thioredoxin reductase-1 http://flybase.org/reports/FBgn0020653 "FBgn0027292, FBgn0028303, FBgn0029045, FBgn0040148, FBgn0066832, FBgn0066833" protein_coding_gene flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR016156 glutathione-disulfide reductase activity ; GO:0004362 | NOT inferred from direct assay antioxidant activity ; GO:0016209 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay thioredoxin-disulfide reductase activity ; GO:0004791 | inferred from direct assay glutathione-disulfide reductase activity ; GO:0004362 | inferred from mutant phenotype antioxidant activity ; GO:0016209 | non-traceable author statement "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR004099, InterPro:IPR012999, InterPro:IPR016156, InterPro:IPR023753 response to oxygen radical ; GO:0000305 | inferred from biological aspect of ancestor with PANTHER:PTN000530450 response to hypoxia ; GO:0001666 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | traceable author statement cell redox homeostasis ; GO:0045454 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "Trxr, DmTrxR-1, TrxR-1, Gr, CG2151, TrxR, Trxr1, dmtrxr-1, DTR, trxr-1, l(1)G0477, l(1)G0481, l(1)G0379, l(1)G0154, gr, GR, anon-WO03040301.187, anon-WO03040301.185, Trxr-1, 2151, Trx, DmTrxR, DmTR, dTrxR, Dm-TrxR, DmTrx, TH, TRR, TRXR1" "IPR004099:Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, IPR006338:Thioredoxin/glutathione reductase selenoprotein, IPR012999:Pyridine nucleotide-disulphide oxidoreductase, class I, active site, IPR016156:FAD/NAD-linked reductase, dimerisation domain, IPR023753:FAD/NAD(P)-binding domain" CG2151 11-Aug-17 DroID_v2017_08 "Drer\gsr, Drer\txnrd1, Drer\si:ch1073-179p4.3" Scer\GLR1 "Cele\gsr-1, Cele\trxr-1, Cele\trxr-2" "Xtro\gsr, Xtro\txnrd2, Xtro\txnrd3, Xtro\txnrd1" "Mmus\Txnrd2, Mmus\Txnrd3, Mmus\Gsr, Mmus\Txnrd1" "Hsap\TXNRD2, Hsap\TXNRD3, Hsap\TXNRD1, Hsap\GSR" embryonic stage -- adult stage "viable,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,fertile,wild-type,partially lethal - majority die,partially,developmental rate defective,male sterile,female,aging defective,lethal - all die before end of larval stage,some die during larval stage,stress response defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "adult abdomen,ganglion mother cell" FBgn0014859 Hr38 Hormone receptor-like in 38 http://flybase.org/reports/FBgn0014859 FBgn0010510 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628 steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement" steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 cuticle development ; GO:0042335 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with HGNC:7980 regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from genetic interaction with Ask1 phagocytosis ; GO:0006909 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:7981 "DHR38, Dhr38, HR38, 38E.7, 38E.3, NR4A4, l(2)02306, CG1864, Hr38, dHR38, hr38, dhr38" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG1864 11-Aug-17 DroID_v2017_08 "Drer\nr4a2a, Drer\nr4a3, Drer\nr4a1, Drer\nr4a2b, Drer\LOC103911606, Drer\ar" - "Cele\nhr-234, Cele\dpr-1, Cele\nhr-6" "Xtro\nr4a1, Xtro\nr4a2" "Mmus\Nr4a1, Mmus\Nr4a2, Mmus\Nr4a3" "Hsap\NR4A1, Hsap\NR4A3, Hsap\NR4A2" " embryonic stage , embryonic stage--pupal stage , larval stage&&prepupal stage " "lethal,recessive,visible,some die during immature adult stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,heat sensitive,viable" "embryonic/larval hemocyte | third instar larval stage,adult cuticle,joint,adult epidermis,leg,pupal epidermis,pupal cuticle" FBgn0015905 ast asteroid http://flybase.org/reports/FBgn0015905 - protein_coding_gene - imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype compound eye photoreceptor fate commitment ; GO:0001752 | inferred from genetic interaction with Sos compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with Egfr compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype - "ast, S[r], Star/asteroid, CG4426" "IPR029060:PIN domain-like, IPR026832:Asteroid" CG4426 11-Aug-17 DroID_v2017_08 "Drer\aste1, Drer\aste1" - - Xtro\aste1 Mmus\Aste1 Hsap\ASTE1 " embryonic stage , larval stage | third instar , embryonic stage -- adult stage " morphogenetic furrow | anterior to

"visible,dominant,recessive,viable,wild-type,female sterile,lethal,partially" "wing vein,ectopic,wing,ommatidium,wing vein L2,wing vein L3,wing vein L4,wing vein L5,eye,embryonic somatic muscle,A1-7 lateral longitudinal muscle 1,A1-7 dorsal oblique muscle 4" FBgn0000482 dor deep orange http://flybase.org/reports/FBgn0000482 - protein_coding_gene "protein binding, bridging ; GO:0030674 | inferred from biological aspect of ancestor with PANTHER:PTN000595174 zinc ion binding ; GO:0008270 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y1I2 syntaxin binding ; GO:0019905 | contributes_to inferred from physical interaction with Syx17" cell division ; GO:0051301 | inferred from mutant phenotype pteridine biosynthetic process ; GO:0006728 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype vesicle docking involved in exocytosis ; GO:0006904 | inferred from biological aspect of ancestor with PANTHER:PTN000595174 lysosomal transport ; GO:0007041 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype regulation of SNARE complex assembly ; GO:0035542 | inferred from biological aspect of ancestor with PANTHER:PTN000595174 endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000004138 ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | traceable author statement eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype eye pigment biosynthetic process ; GO:0006726 | traceable author statement protein targeting to lysosome ; GO:0006622 | inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | non-traceable author statement border follicle cell migration ; GO:0007298 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype lysosome organization ; GO:0007040 | inferred from biological aspect of ancestor with PANTHER:PTN000595174 endosome organization ; GO:0007032 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype regulation of SNARE complex assembly ; GO:0035542 | inferred from sequence or structural similarity with SGD:S000004138 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay synapse ; GO:0045202 | inferred from mutant phenotype HOPS complex ; GO:0030897 | inferred from sequence or structural similarity with SGD:S000004138 HOPS complex ; GO:0030897 | inferred from mutant phenotype HOPS complex ; GO:0030897 | inferred from direct assay CORVET complex ; GO:0033263 | inferred from sequence or structural similarity with SGD:S000004138 "dor, Deep-orange, Dor, EG:171E4.1, CG3093, l(1)7, dor1, l(1)76, l(1)2Bw, l(1)2Be, Vps18, Dof, FI09617" "IPR007810:Pep3/Vps18/deep orange, IPR000547:Clathrin, heavy chain/VPS, 7-fold repeat, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3093 11-Aug-17 DroID_v2017_08 Drer\vps18 Scer\PEP3 Cele\vps-18 Xtro\vps18 Mmus\Vps18 Hsap\VPS18 embryonic stage -- adult stage " larval stage , pupal stage , adult stage | female , embryonic stage , adult stage | male " ovary

"lethal,viable,visible,heat sensitive,cold sensitive,short lived,female,male,eye color defective,recessive,lethal - all die before end of larval stage,some die during larval stage,male sterile,melanotic mass phenotype,male fertile,female fertile,reduced,cell death defective,decreased cell death,lethal - all die before end of pupal stage,some die during pupal stage,sterile,somatic clone,male limited,some die during third instar larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage" "eye,heat sensitive,thorax & macrochaeta | conditional cs,wing,late endosome,pigment cell,synapse,bouton,egg chamber,nurse cell,spermatogonial cyst,male germline cell,ovariole,germline clone,egg,Malpighian tubule,adult foregut,adult midgut,adult hindgut,somatic clone,eye photoreceptor cell,endosome | somatic clone,border follicle cell,polar follicle cell,embryonic/larval fat body,nutrition conditional,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0040985 CG6115 - http://flybase.org/reports/FBgn0040985 protein_coding_gene - - - "BcDNA:GH16758, CG6115" IPR008011:Complex 1 LYR protein CG6115 11-Aug-17 DroID_v2017_08 "Drer\lyrm5b, Drer\lyrm5a" - Cele\Y42A5A.5 Xtro\lyrm5 Mmus\Lyrm5 Hsap\ETFRF1 "viable,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02931 E -0.357015753 -1.028328435 -2.012748375 0.190264759 -0.643274271 -0.630016028 FBgn0060380 l(3)S135107 lethal (3) S135107 http://flybase.org/reports/FBgn0060380 gene - - - "1351/07, l(3)S135107" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0060960 l(3)S032414 lethal (3) S032414 http://flybase.org/reports/FBgn0060960 gene - - - "0324/14, l(3)S032414" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0029873 CG3918 - http://flybase.org/reports/FBgn0029873 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - CG3918 "IPR001878:Zinc finger, CCHC-type" CG3918 11-Aug-17 DroID_v2017_08 "Drer\tulp1a, Drer\fam133b, Drer\srek1ip1" - "Cele\Y119C1B.1, Cele\C13F10.7" Xtro\srek1ip1 Mmus\Srek1ip1 "Hsap\SREK1IP1, Hsap\FAM133B" "viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" DRSC28834 K -1.549512016 0.259407506 FBgn0036741 CG7510 - http://flybase.org/reports/FBgn0036741 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004776 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR000591 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004776 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001482048 "anon-74EFa, CG7510" "IPR000591:DEP domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR004776:Membrane transport protein" CG7510 11-Aug-17 DroID_v2017_08 "Drer\gpr155b, Drer\gpr155a" - - Xtro\gpr155 Mmus\Gpr155 Hsap\GPR155 "partially lethal - majority die,visible" mesothoracic tergum FBgn0034109 CG7747 - http://flybase.org/reports/FBgn0034109 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:9261" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:9261" nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:9261 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG7747, CYC4" "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR027799:Replication termination factor 2, RING-finger, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7747 11-Aug-17 DroID_v2017_08 "Drer\ppil2, Drer\si:rp71-15d4.1, Drer\pxnb, Drer\ppil3, Drer\pxna" "Scer\CPR2, Scer\CPR5" "Cele\cyn-4, Cele\cyn-10, Cele\pxl-1" "Xtro\ppil2, Xtro\pxn, Xtro\tgfb1i1, Xtro\ppil3" "Mmus\Ppil2, Mmus\Pxn, Mmus\Ppil3, Mmus\Tgfb1i1, Mmus\Lpxn" "Hsap\LPXN, Hsap\PPIL2, Hsap\PXN, Hsap\TGFB1I1, Hsap\PPIL3" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0031298 Atg4a Autophagy-related 4a http://flybase.org/reports/FBgn0031298 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity with SGD:S000005167 larval midgut cell programmed cell death ; GO:0035096 | NOT inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 nucleophagy ; GO:0044804 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 regulation of autophagy ; GO:0010506 | inferred from mutant phenotype protein delipidation ; GO:0051697 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 autophagy ; GO:0006914 | inferred from mutant phenotype C-terminal protein lipidation ; GO:0006501 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype protein targeting to membrane ; GO:0006612 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 cytosol ; GO:0005829 | inferred from sequence or structural similarity with SGD:S000005167 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000504505 "Atg4a, CG4428, atg4, Atg4, ATG4, APG4, AUT2" IPR005078:Peptidase C54 CG4428 11-Aug-17 DroID_v2017_08 "Drer\atg4b, Drer\atg4a, Drer\atg4c, Drer\atg4db, Drer\atg4da" Scer\ATG4 "Cele\atg-4.2, Cele\atg-4.1" "Xtro\atg4a, Xtro\atg4d, Xtro\atg4b, Xtro\atg4c" "Mmus\Atg4b, Mmus\Atg4a, Mmus\Atg4d, Mmus\Atg4c" "Hsap\ATG4A, Hsap\ATG4D, Hsap\ATG4B, Hsap\ATG4C" "starvation stress response defective,somatic clone,viable" "embryonic/larval fat body,somatic clone | third instar larval stage,lysosome | somatic clone | third instar larval stage,autophagic vacuole | somatic clone | third instar larval stage" FBgn0003996 w white http://flybase.org/reports/FBgn0003996 "FBgn0000561, FBgn0026792, FBgn0026850" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 guanine-transporting ATPase activity ; GO:0008558 | inferred from mutant phenotype transmembrane signaling receptor activity ; GO:0004888 | non-traceable author statement ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 synaptic vesicle amine transmembrane transporter activity ; GO:0005430 | inferred from mutant phenotype eye pigment precursor transporter activity ; GO:0005395 | inferred from mutant phenotype" ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype eye pigment precursor transport ; GO:0006856 | traceable author statement male courtship behavior ; GO:0008049 | inferred from mutant phenotype transmembrane transport ; GO:0055085 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype eye pigment metabolic process ; GO:0042441 | traceable author statement cGMP transport ; GO:0070731 | inferred from mutant phenotype histamine uptake ; GO:0051615 | inferred from genetic interaction with e inferred from genetic interaction with t aminergic neurotransmitter loading into synaptic vesicle ; GO:0015842 | inferred from mutant phenotype cellular biogenic amine biosynthetic process ; GO:0042401 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 cytoplasmic vesicle ; GO:0031410 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 pigment granule ; GO:0048770 | inferred from direct assay "w, CG2759, BACN33B1.1, EG:BACN33B1.1, w(AT)[[13]], DMWHITE, m(g), e(g), c23, Hid, W, mw, white" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR005284:Pigment precursor permease, IPR013525:ABC-2 type transporter, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2759 11-Aug-17 DroID_v2017_08 "Drer\abcg4b, Drer\abcg8, Drer\abcg2a, Drer\abcg1, Drer\abcg4a, Drer\abcg2c, Drer\abcg2d, Drer\abcg5, Drer\abcg2b" "Scer\PDR12, Scer\PDR10, Scer\PDR18, Scer\SNQ2, Scer\PDR5, Scer\PDR11, Scer\PDR15, Scer\AUS1, Scer\ADP1, Scer\YOL075C" "Cele\wht-1, Cele\wht-7, Cele\wht-2, Cele\wht-4, Cele\wht-6, Cele\wht-3, Cele\wht-5, Cele\wht-8" "Xtro\abcg8, Xtro\abcg5, Xtro\abcg2" "Mmus\Abcg3, Mmus\Abcg8, Mmus\Abcg2, Mmus\Abcg5, Mmus\Abcg4, Mmus\Abcg1" "Hsap\ABCG1, Hsap\ABCG4, Hsap\ABCG2, Hsap\ABCG8, Hsap\ABCG5" " larval stage , adult stage | female , adult stage | male , adult stage " head

"visible,recessive,eye color defective,conditional,courtship behavior defective,male,dominant,female,suppressor of variegation,viable,fertile,cold sensitive,heat sensitive,gravitaxis defective,chemical conditional,male fertile,male limited,wild-type,behavior defective,semidominant,chemical resistant,locomotor behavior defective,memory defective,long lived,modifier of variegation,body color defective" "pigment cell,embryonic/larval Malpighian tubule,testis pigment cell,Malpighian tubule,eye,conditional,male,female,ventral,ocellus,testis,cold sensitive,main segment of Malpighian tubule,ocellus pigment granule,retina,ommatidium,adult cuticle" FBgn0031973 Spn28Dc Serpin 28Dc http://flybase.org/reports/FBgn0031973 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model negative regulation of proteolysis ; GO:0045861 | inferred from mutant phenotype negative regulation of melanization defense response ; GO:0035009 | inferred from mutant phenotype response to wounding ; GO:0009611 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from mutant phenotype "Dm-Spn28D, CG7219, spn28D, Spn28Dc, Spn28D" "IPR000215:Serpin family, IPR023796:Serpin domain" CG7219 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-416d2.3, Drer\serpinb1l3, Drer\serpine2, Drer\serpinb1l2, Drer\serpinh1b, Drer\serpinc1, Drer\serpinb1, Drer\serpine1, Drer\agt, Drer\serpina10a, Drer\serpinh1a, Drer\serpinb1l4, Drer\serpinb1l1, Drer\serpinh2, Drer\zgc:173729, Drer\serpine3" - Cele\srp-1 "Xtro\agt, Xtro\serpinh1" "Mmus\Serpinb9e, Mmus\Serpine3, Mmus\Serpinb1b, Mmus\Serpinb8, Mmus\Serpinb9g, Mmus\Serpinb9f, Mmus\Agt, Mmus\Serpinb6c, Mmus\Serpinb5, Mmus\Serpine2, Mmus\Serpinb6a, Mmus\Serping1, Mmus\Serpinb9c, Mmus\Serpinb3d, Mmus\Serpinb6e, Mmus\Serpinb9b, Mmus\Serpinb9d, Mmus\Serpinb13, Mmus\Serpine1, Mmus\Serpinb2, Mmus\Gm11397, Mmus\Serpinb3a, Mmus\Serpinb1c, Mmus\Serpinb6d, Mmus\Serpinb9, Mmus\Serpinb10, Mmus\Serpinb3c, Mmus\Serpinc1, Mmus\Serpinb11, Mmus\Serpinb1a, Mmus\Serpinb6b, Mmus\Serpinb12, Mmus\Serpina10, Mmus\Serpinh1, Mmus\Serpinb3b" "Hsap\SERPINB9, Hsap\SERPINB2, Hsap\SERPINB5, Hsap\AGT, Hsap\SERPINE2, Hsap\SERPINB4, Hsap\SERPINB8, Hsap\SERPINB12, Hsap\SERPINB6, Hsap\HMSD, Hsap\SERPINB11, Hsap\SERPINE1, Hsap\SERPINA12, Hsap\SERPINE3, Hsap\SERPINB10, Hsap\SERPINH1, Hsap\SERPINB13, Hsap\SERPINB3, Hsap\SERPING1, Hsap\SERPINA10, Hsap\SERPINB1, Hsap\SERPINC1" "viable,body color defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,recessive,wound healing defective,melanotic mass phenotype" "ptilinum,ptilinal suture,adult cuticle,melanotic mass,adult spiracle,haltere foramen,adult external abdomen,trachea,spiracle,pupa" FBgn0003312 sad shadow http://flybase.org/reports/FBgn0003312 FBgn0037957 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 ecdysteroid 2-hydroxylase activity ; GO:0042768 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 central nervous system development ; GO:0007417 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from direct assay dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay "Cyp315a1, CYP315A1, 315a1, Sad, CG14728, sad" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG14728 11-Aug-17 DroID_v2017_08 "Drer\cyp27a1.4, Drer\cyp27a7, Drer\cyp11c1, Drer\cyp11a1, Drer\si:dkey-91i10.3, Drer\zgc:136333, Drer\cyp27a1.2, Drer\si:ch211-113j14.1, Drer\cyp27c1, Drer\cyp27b1, Drer\cyp11a2, Drer\cyp24a1" - "Cele\cyp-44A1, Cele\ZK177.4, Cele\cyp-13A10" "Xtro\cyp11a1, Xtro\cyp27c1, Xtro\cyp27a1, Xtro\cyp24a1, Xtro\cyp27b1, Xtro\LOC100145331" "Mmus\Cyp11a1, Mmus\Cyp27a1, Mmus\Cyp24a1, Mmus\Cyp27b1, Mmus\Cyp11b1, Mmus\Cyp11b2" "Hsap\CYP27B1, Hsap\CYP24A1, Hsap\CYP27C1, Hsap\CYP11B1, Hsap\CYP11B2, Hsap\CYP27A1, Hsap\CYP11A1" "lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,recessive,viable" "presumptive embryonic/larval central nervous system,cephalopharyngeal skeleton,embryonic/first instar larval cuticle,embryo,posterior,mitochondrion,axonExel7310),midgut constriction,embryonic/larval tracheal system,commissure,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,dorsal closure embryo,embryonic ventral epidermis,ventral nerve cord,embryonic/larval midgut,embryonic/larval foregut,embryonic/larval hindgut,embryonic/larval neuron,ectopic,longitudinal connective,glial cell,midline glial cell" FBgn0000394 cv crossveinless http://flybase.org/reports/FBgn0000394 FBgn0029790 protein_coding_gene - jump response ; GO:0007630 | inferred from mutant phenotype positive regulation of muscle organ development ; GO:0048636 | inferred from mutant phenotype - "tsg2, CG12410, cv-1, Tsg2, cv, Cv" IPR006761:Twisted gastrulation (Tsg) protein CG12410 11-Aug-17 DroID_v2017_08 "Drer\twsg1b, Drer\twsg1a" - - "Xtro\twsg1, Xtro\twsg2" Mmus\Twsg1 Hsap\TWSG1 "viable,fertile,visible,recessive,jumping defective,partially,partially lethal - majority die,body color defective" "eye,anterior crossvein,posterior crossvein,crossvein,wing vein,wing vein L3,wing vein L4,mesothoracic extracoxal depressor muscle 66,thoracic adult muscle precursor cell,mesothoracic tergum" FBgn0011722 Tig Tiggrin http://flybase.org/reports/FBgn0011722 - protein_coding_gene "integrin binding ; GO:0005178 | inferred from physical interaction with if, mys" cell adhesion mediated by integrin ; GO:0033627 | inferred from direct assay substrate adhesion-dependent cell spreading ; GO:0034446 | inferred from direct assay axon guidance ; GO:0007411 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of cell adhesion mediated by integrin ; GO:0033628 | inferred from genetic interaction with pgant3 cell-substrate adhesion ; GO:0031589 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype extracellular matrix ; GO:0031012 | inferred from direct assay basement membrane ; GO:0005604 | inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity inferred from direct assay "tig, Tig, CT36389, TIG, CG11527" "IPR016084:Haem oxygenase-like, multi-helical" CG11527 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 14 , embryonic stage | stage 12 " " fat body

, hemocyte

" " embryonic stage , embryonic stage&&larval stage , adult stage " " metameric furrow

, hemocyte

, commissure

, muscle attachment site

, mesothoracic extracoxal depressor muscle 66

, embryonic/larval fat body

" "partially lethal - majority die,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "abdominal 7 segment border muscle,embryonic/larval somatic muscle,adult abdomen,wing,pupa,air bubble,fascicle,abdominal 2 ventral longitudinal muscle 3,abdominal 3 ventral longitudinal muscle 3,abdominal 4 ventral longitudinal muscle 3,abdominal 5 ventral longitudinal muscle 3,abdominal 6 ventral longitudinal muscle 3,abdominal 7 ventral longitudinal muscle 3,abdominal 2 ventral longitudinal muscle 4,abdominal 3 ventral longitudinal muscle 4,abdominal 4 ventral longitudinal muscle 4,abdominal 5 ventral longitudinal muscle 4,abdominal 6 ventral longitudinal muscle 4,abdominal 7 ventral longitudinal muscle 4,abdominal 2 lateral oblique muscle 1,abdominal 3 lateral oblique muscle 1,abdominal 4 lateral oblique muscle 1,abdominal 5 lateral oblique muscle 1,abdominal 6 lateral oblique muscle 1,abdominal 7 lateral oblique muscle 1,abdominal 2 segment border muscle,abdominal 3 segment border muscle,abdominal 4 segment border muscle,abdominal 5 segment border muscle,abdominal 6 segment border muscle" FBgn0002931 net net http://flybase.org/reports/FBgn0002931 FBgn0031215 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HLH54F" "cell differentiation ; GO:0030154 | inferred from electronic annotation with InterPro:IPR032660 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with HLH54F" - "CG11450, Shout, Group IId, shout, net, bHLHc42" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR032660:Protein atonal homologue 8" CG11450 11-Aug-17 DroID_v2017_08 Drer\atoh8 - - - "Mmus\Atoh8, Mmus\Atoh1" Hsap\ATOH8 "visible,dominant,recessive,semidominant,wild-type,viable,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing vein,ectopic,1st posterior cell,marginal cell,submarginal cell,2nd posterior cell,3rd posterior cell,distal,posterior cell,wing vein L3,wing vein L4,wing vein L5" FBgn0000928 fs(1)Yb female sterile (1) Yb http://flybase.org/reports/FBgn0000928 "FBgn0000897, FBgn0024974" protein_coding_gene - "ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype somatic stem cell division ; GO:0048103 | traceable author statement germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype negative regulation of transposition, RNA-mediated ; GO:0010526 | inferred from biological aspect of ancestor with PANTHER:PTN001476977 germ-line stem cell division ; GO:0042078 | traceable author statement germ cell development ; GO:0007281 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity Yb body ; GO:0070725 | inferred from direct assay "Yb, EG:95B7.8, CG2706, fs(1)Y[b], nov, fs(1)M104, fs(1)Yb, YB, yb" IPR027417:P-loop containing nucleoside triphosphate hydrolase CG2706 11-Aug-17 DroID_v2017_08 "Drer\ddx42, Drer\ddx46" Scer\PRP5 - "Xtro\ddx46, Xtro\ddx42" "Mmus\Ddx42, Mmus\Ddx46" "Hsap\DDX46, Hsap\DDX42, Hsap\TDRD12" " adult stage && oogenesis stage , larval stage && pupal stage && adult stage " " terminal filament

, ovariole

, epithelial sheath

" "female sterile,recessive,viable,male fertile,female semi-sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type,female fertile" "egg chamber,germarium,germline stem cell,follicle cell,egg,dorsal appendage,basal stalk,ovary,germline cyst,spectrosome,ovariole,maternal effect,nurse cell spectrosome,female germline stem cell,supernumerary,interfollicle cell" FBgn0028426 JhI-1 Juvenile hormone-inducible protein 1 http://flybase.org/reports/FBgn0028426 protein_coding_gene "3'-tRNA processing endoribonuclease activity ; GO:0042781 | inferred from biological aspect of ancestor with PANTHER:PTN000284960 endoribonuclease activity, producing 5'-phosphomonoesters ; GO:0016891 | inferred from mutant phenotype" "germ cell proliferation ; GO:0036093 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | inferred from mutant phenotype tRNA splicing, via endonucleolytic cleavage and ligation ; GO:0006388 | inferred from mutant phenotype polycistronic mRNA processing ; GO:0031426 | inferred from mutant phenotype tRNA export from nucleus ; GO:0006409 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype tRNA 3'-end processing ; GO:0042780 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype regulation of cell growth ; GO:0001558 | inferred from mutant phenotype mitochondrial tRNA 3'-trailer cleavage, endonucleolytic ; GO:0072684 | inferred from biological aspect of ancestor with PANTHER:PTN000284963" nucleus ; GO:0005634 | non-traceable author statement mitochondrion ; GO:0005739 | non-traceable author statement mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000284963 "dRNaseZ, CG3298, JhI-1, tRNase Z, JHI-1, tRNAse Z, dtRNaseZ, dRNase Z, RNZ, jhI-1" "IPR001279:Metallo-beta-lactamase, IPR027794:tRNase Z endonuclease" CG3298 11-Aug-17 DroID_v2017_08 "Drer\elac2, Drer\elac1" Scer\TRZ1 Cele\hoe-1 "Xtro\elac2, Xtro\elac1" "Mmus\Elac1, Mmus\Elac2" "Hsap\ELAC1, Hsap\ELAC2" "lethal,lethal - all die before end of second instar larval stage,decreased cell size,cell autonomous,somatic clone,size defective,sterile,temperature conditional,lethal - all die before end of larval stage,mitotic cell cycle defective,neuroanatomy defective,partially lethal - majority die,some die during pharate adult stage,viable,visible,female limited,decreased cell growth,some die during third instar larval stage,recessive" "fat body,cell autonomous,somatic clone,eye disc,egg chamber,temperature conditional,oocyte,supernumerary,nurse cell,follicle cell,female germline cyst,testis,spermatogonium,spermatid,male germline cyst,Nebenkern,wing disc,ganglion mother cell,chaeta,trichogen cell,mesothoracic tergum,dorsal wing blade,female limited,wing blade,scutellum,eye,ommatidium,eye-antennal disc,head capsule" FBgn0037351 RpL13A Ribosomal protein L13A http://flybase.org/reports/FBgn0037351 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000166701 "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR005755, InterPro:IPR005822, InterPro:IPR023563 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with mam inferred from genetic interaction with N" large ribosomal subunit ; GO:0015934 | inferred from electronic annotation with InterPro:IPR005755 cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "CG1475, L13a2, cg1475, bs25f04.y1, anon-EST:fe1A5, anon-EST:Posey125, RpL13A, L13A, M(3)83B, Rp L13A, chr3R:1451210..1451407" "IPR005755:Ribosomal protein L13, eukaryotic/archaeal, IPR005822:Ribosomal protein L13, IPR023563:Ribosomal protein L13, conserved site" CG1475 11-Aug-17 DroID_v2017_08 Drer\rpl13a "Scer\RPL16A, Scer\RPL16B" Cele\rpl-16 Xtro\rpl13a "Mmus\Rpl13a, Mmus\Flt3l" Hsap\RPL13A "Minute,dominant,visible,lethal" macrochaeta DRSC12265 EK 0.103944708 -0.519731393 -1.126374924 -4.553400539 1.928877073 1.350087872 FBgn0010067 M(3)39b M(3)39b http://flybase.org/reports/FBgn0010067 - gene - - - M(3)39b - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,Minute,visible" macrochaeta FBgn0021872 Xbp1 X box binding protein-1 http://flybase.org/reports/FBgn0021872 "FBgn0025990, FBgn0034593" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from sequence or structural similarity with UniProtKB:P17861 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000329394" response to endoplasmic reticulum stress ; GO:0034976 | inferred from direct assay wing disc development ; GO:0035220 | inferred from mutant phenotype inferred from genetic interaction with Bx inferred from genetic interaction with ap positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response ; GO:0006990 | inferred from direct assay chaeta development ; GO:0022416 | inferred from mutant phenotype inferred from genetic interaction with Ssdp inferred from genetic interaction with Chi endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from direct assay response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000329443 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P17861 "xbp1, CG9415, clone 1.41, 138/3, l(2)k13803, anon-EST:Liang-1.41, Xbp1, Dxbp-1, XBP-1, XBP1, CG 9415, xbp-1, Xbp-1, dXbp-1, XbpI, DM18" IPR004827:Basic-leucine zipper domain CG9415 11-Aug-17 DroID_v2017_08 Drer\xbp1 - Cele\xbp-1 Xtro\xbp1 Mmus\Xbp1 Hsap\XBP1 "lethal,recessive,hypoactive,developmental rate defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,increased cell death,neuroanatomy defective,partially lethal - majority die,viable,visible,eye color defective" "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous,imaginal disc,wing,macrochaeta,supernumerary,scutum,scutellar bristle,chaeta,tormogen cell,eye,retina,photoreceptor cell,eye photoreceptor cell" FBgn0041733 mer-on-3 merlin on 3 http://flybase.org/reports/FBgn0041733 gene - - - "mer-on-3, mer" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical resistant,dominant,melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,tumorigenic" "salivary gland,melanotic mass,polytene chromosome,embryonic/larval brain" FBgn0035005 CG3483 - http://flybase.org/reports/FBgn0035005 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR024084" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001804, InterPro:IPR024084" - "anon-WO0140519.111, CG3483" IPR024084:Isopropylmalate dehydrogenase-like domain CG3483 11-Aug-17 DroID_v2017_08 Drer\idh3a "Scer\LEU2, Scer\IDH2, Scer\LYS12" Cele\idha-1 Xtro\idh3a Mmus\Idh3a Hsap\IDH3A viable FBgn0066333 pon::pins pon::raps http://flybase.org/reports/FBgn0066333 engineered_fusion_gene - - - "pon::raps, pon::pins" - - 11-Aug-17 DroID_v2017_08 - - - - - - cell polarity defective neuroblast FBgn0065805 l(2)SH0396 lethal (2) SH0396 http://flybase.org/reports/FBgn0065805 gene - - - "l(2)SH0396, l(2)SH2 0396" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000562 egl egalitarian http://flybase.org/reports/FBgn0000562 - protein_coding_gene 3'-5' exonuclease activity ; GO:0008408 | inferred from electronic annotation with InterPro:IPR002562 mRNA binding ; GO:0003729 | inferred from direct assay nucleobase-containing compound metabolic process ; GO:0006139 | inferred from electronic annotation with InterPro:IPR002562 regulation of oskar mRNA translation ; GO:0046011 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | traceable author statement germarium-derived oocyte fate determination ; GO:0007294 | non-traceable author statement mRNA transport ; GO:0051028 | inferred from direct assay mRNA transport ; GO:0051028 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype intracellular mRNA localization involved in pattern specification process ; GO:0060810 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from direct assay germarium-derived oocyte fate determination ; GO:0007294 | traceable author statement oocyte nucleus migration involved in oocyte dorsal/ventral axis specification ; GO:0007312 | traceable author statement intracellular mRNA localization ; GO:0008298 | traceable author statement bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype - "egl, Egl, CG4051, egal, EGL" "IPR002562:3'-5' exonuclease domain, IPR012337:Ribonuclease H-like domain" CG4051 11-Aug-17 DroID_v2017_08 Drer\exd1 - Cele\egal-1 Xtro\exd1 Mmus\Exd1 Hsap\EXD1 adult stage && oogenesis stage oocyte

"O, adult stage && oogenesis stage " " germarium region 1 && germline cyst

, germarium region 3 && oocyte

posterior , germarium region 2b && presumptive oocyte | anterior , germarium region 2a && presumptive oocyte | anterior , germarium

" "female sterile,recessive,neuroanatomy defective,wild-type,viable" "ovary,germline cyst,vitellarium,nurse cell ring canal,anterior fascicle & synapse,embryonic/larval salivary gland,centrosome,oocyte,synaptonemal complex,synaptonemal complex | ectopic,nurse cell,ectopic,germarium region 2a,embryonic neuroblast,embryonic neuroblast & spindle,egg chamber,supernumerary,microtubule organizing centerbw-S46),microtubulebw-S46),embryonic epidermis,synapse,bouton,karyosome,lipid particlenos.UTR.THsimVP16,border follicle cell" FBgn0060993 l(3)S027335b lethal (3) S027335b http://flybase.org/reports/FBgn0060993 gene - - - "0273/35, l(3)S027335b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0028692 Rpn2 Regulatory particle non-ATPase 2 http://flybase.org/reports/FBgn0028692 protein_coding_gene enzyme regulator activity ; GO:0030234 | inferred from electronic annotation with InterPro:IPR016642 zinc ion binding ; GO:0008270 | inferred from direct assay regulation of protein catabolic process ; GO:0042176 | inferred from electronic annotation with InterPro:IPR016642 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 "proteasome complex ; GO:0000502 | inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000001337 proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9554 inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from direct assay" "p110, dRpn2, CG11888, Rpn2, PSMC1, 11888, S1, RPN2, rpn2" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR016642:26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit, IPR002015:Proteasome/cyclosome repeat" CG11888 11-Aug-17 DroID_v2017_08 "Drer\psmd2, Drer\psmd1" Scer\RPN2 Cele\rpn-2 Xtro\psmd1 Mmus\Psmd1 Hsap\PSMD1 "lethal,decreased cell size,somatic clone" "fat body,somatic clone,autolysosomeCg.PA,autophagic vacuoleCg.PA" DRSC16839 IEK -2.709784312 -5.922021597 -3.147256482 -3.783050735 -1.013027346 -1.83673734 FBgn0028484 Ack Activated Cdc42 kinase http://flybase.org/reports/FBgn0028484 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 SH2 domain binding ; GO:0042169 | inferred from direct assay" peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of hippo signaling ; GO:0035332 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with hid dorsal closure ; GO:0007391 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from biological aspect of ancestor with PANTHER:PTN001231165 protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 spermatid development ; GO:0007286 | inferred from mutant phenotype peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 cellular protein localization ; GO:0034613 | inferred from mutant phenotype cell periphery ; GO:0071944 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 clathrin-coated vesicle ; GO:0030136 | inferred from direct assay "DACK, DAck, p145, ACK, CG14992, ACK2, BcDNA:GH10777, Ack" "IPR015940:Ubiquitin-associated domain, IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR009060:UBA-like, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG14992 11-Aug-17 DroID_v2017_08 "Drer\tnk2b, Drer\LOC100148041, Drer\tnk2" - "Cele\kin-32, Cele\sid-3" Xtro\tnk2 "Mmus\Tnk1, Mmus\Tnk2, Mmus\Syk" "Hsap\TNK1, Hsap\TNK2" "viable,visible,male sterile,female fertile,partially lethal - majority die,heat sensitive,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,some die during pupal stage" "sperm individualization complex,individualization stage spermatid,eye,elongation stage spermatid,spermatozoon,interommatidial bristle,supernumerary,pigment cell,embryo | dorsal closure stage,embryonic/first instar larval cuticle,heat sensitive,embryo,ommatidium,embryonic head,wing,wing vein,ectopic,mesothoracic tergum" FBgn0005194 l(2)S61 lethal of Seto 61 http://flybase.org/reports/FBgn0005194 - gene - - - l(2)S61 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" "wing,leg,prepupa" FBgn0036153 CG7573 - http://flybase.org/reports/FBgn0036153 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000012712 CAAX-box protein processing ; GO:0071586 | inferred from biological aspect of ancestor with PANTHER:PTN000012712 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000012714 CG7573 "IPR001915:Peptidase M48, IPR027057:CAAX prenyl protease 1, IPR032456:CAAX prenyl protease 1, N-terminal" CG7573 11-Aug-17 DroID_v2017_08 Drer\zmpste24 Scer\STE24 Cele\fce-1 Xtro\zmpste24 Mmus\Zmpste24 Hsap\ZMPSTE24 "viable,fertile" FBgn0003406 sic sichel http://flybase.org/reports/FBgn0003406 - gene - - - sic - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,cold sensitive,some die during embryonic stage,lethal" "denticle belt,maternal effect,cephalopharyngeal skeleton,embryo,cold sensitive,syncytial blastoderm embryo,ventral arm of pharyngeal sclerite" FBgn0033731 Cpr49Ah Cuticular protein 49Ah http://flybase.org/reports/FBgn0033731 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr49Ah, CG8515, DmelCpr49Ah" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8515 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" DRSC07204 K -0.149871348 0.330760995 -0.604172435 -0.282381074 1.87566841 -0.019478545 FBgn0036248 ssp sunspot http://flybase.org/reports/FBgn0036248 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 beta-catenin binding ; GO:0008013 | inferred from physical interaction with arm "positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype positive regulation of DNA endoreduplication ; GO:0032877 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" nuclear body ; GO:0016604 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay "Ssp, ssp, CG17153" "IPR003656:Zinc finger, BED-type, IPR026095:Myb/SANT-like DNA-binding domain-containing protein" CG17153 11-Aug-17 DroID_v2017_08 Drer\msantd1 Scer\RFA3 - - Mmus\Msantd1 "Hsap\NFKBIA, Hsap\MSANTD1" "melanotic mass phenotype,decreased cell number,somatic clone,endomitotic cell cycle defective,lethal - all die before end of larval stage,some die during third instar larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "imaginal disc,embryonic/larval central nervous system,nucleus,embryonic/larval salivary gland,nucleusdpp.blk1,embryonic/larval neuroblast,mesothoracic tergum" DRSC10252 K -0.416058253 -0.94582291 -1.344245275 -0.40928378 1.502665533 -0.441335137 FBgn0003601 Su(var)3-10 Suppressor of variegation 3-10 http://flybase.org/reports/FBgn0003601 - gene - - - "Su-var(3)10, Su(var)3-10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0051989 Cap-D3 Chromosome associated protein D3 http://flybase.org/reports/FBgn0051989 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay methylated histone binding ; GO:0035064 | inferred from sequence or structural similarity with HGNC:28952 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000368592 mitotic chromosome condensation ; GO:0007076 | inferred from biological aspect of ancestor with PANTHER:PTN000368592 regulation of DNA double-strand break processing ; GO:1903775 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype negative regulation of mitotic recombination ; GO:0045950 | inferred from mutant phenotype chromosome separation ; GO:0051304 | inferred from genetic interaction with Cap-H2 male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype meiotic chromosome condensation ; GO:0010032 | inferred from biological aspect of ancestor with PANTHER:PTN000368592 "condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:28952 condensed chromosome, centromeric region ; GO:0000779 | inferred from biological aspect of ancestor with PANTHER:PTN000368592 chromosome, centromeric region ; GO:0000775 | colocalizes_with inferred from direct assay nuclear condensin complex ; GO:0000799 | inferred from biological aspect of ancestor with PANTHER:PTN000368592 nucleus ; GO:0005634 | inferred from direct assay" "CG6922, CG14019, BcDNA:RE74832, CG31989, Cap-D3, CAP-D3, CAP-D2, dCap-D3, cap-D3, CapD3" "IPR016024:Armadillo-type fold, IPR012371:Condensin-2 complex subunit D3, IPR026971:Condensin subunit 1/Condensin-2 complex subunit D3, IPR011989:Armadillo-like helical" CG31989 11-Aug-17 DroID_v2017_08 Drer\ncapd3 - "Cele\hcp-6, Cele\dpy-28, Cele\srbc-45" "Xtro\ncapd3, Xtro\ncapd2" "Mmus\Ncapd3, Mmus\Ncapd2" "Hsap\NCAPD2, Hsap\NCAPD3" "viable,male fertile,female fertile,male sterile,meiotic cell cycle defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,immune response defective" "primary spermatocyte in meiotic prophase I,primary spermatocyte in meiotic anaphase I,polytene chromosome & nurse cellExel7023),trichogen cell" FBgn0061515 endos endosulfine http://flybase.org/reports/FBgn0061515 protein_coding_gene protein phosphatase inhibitor activity ; GO:0004864 | inferred from direct assay regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype response to nutrient ; GO:0007584 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype water homeostasis ; GO:0030104 | inferred from mutant phenotype negative regulation of protein dephosphorylation ; GO:0035308 | inferred from direct assay regulation of meiotic cell cycle ; GO:0051445 | inferred from mutant phenotype negative regulation of phosphoprotein phosphatase activity ; GO:0032515 | inferred from genetic interaction with mts inferred from genetic interaction with tws inferred from genetic interaction with Pp2A-29B negative regulation of catalytic activity ; GO:0043086 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001309504 "CG6513, l(3)S067006, 0670/06, dendos, endos, End" IPR006760:Endosulphine CG6513 11-Aug-17 DroID_v2017_08 "Drer\ensab, Drer\LOC103909813, Drer\ensaa, Drer\arpp19a, Drer\arpp19b" "Scer\IGO2, Scer\IGO1" Cele\ensa-1 "Xtro\ensa, Xtro\arpp19" "Mmus\Ensa, Mmus\Arpp19" "Hsap\ARPP19, Hsap\ENSA" larval stage | third instar " Malpighian tubule

, larval brain

, embryonic/larval proventriculus

" "lethal,mitotic cell cycle defective,meiotic cell cycle defective,female sterile,recessive,visible,male sterile,lethal - all die before end of P-stage,some die during pharate adult stage,male fertile,neuroanatomy defective,partially lethal - majority die" "embryonic/larval neuroblast,stage S14 oocyte,follicle cell,egg,germline clone,oocyte,spindle & oocyte,spindle | embryonic stage | maternal effect,wing,tergite,leg,chaeta,embryonic/larval brain" DRSC10658 IK 1.710128713 1.215033052 0.865044774 0.521656318 0.316794094 1.962498917 FBgn0002441 l(3)mbt lethal (3) malignant brain tumor http://flybase.org/reports/FBgn0002441 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002515 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR002515 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR003118 protein binding ; GO:0005515 | inferred from physical interaction with E2f1 chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay" negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype syncytial nuclear migration ; GO:0035190 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of preblastoderm mitotic cell cycle ; GO:0007347 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from mutant phenotype Myb complex ; GO:0031523 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "l(3)mbt, L(3)MBT, L(3)MBT/LIN-61, MBT, l(3)malignant braintumor, mbt, CG5954, L(3)mbt, L3mbt, dl(3)MBT, dL(3)mbt" "IPR003118:Pointed domain, IPR004092:Mbt repeat, IPR013761:Sterile alpha motif/pointed domain, IPR002515:Zinc finger, C2HC-type" CG5954 11-Aug-17 DroID_v2017_08 "Drer\samd13, Drer\l3mbtl4, Drer\scml4, Drer\phc3, Drer\l3mbtl1b, Drer\l3mbtl1, Drer\si:ch211-230g15.5, Drer\samd1a, Drer\sfmbt2, Drer\samd1b, Drer\l3mbtl3" - Cele\lin-61 "Xtro\l3mbtl1, Xtro\l3mbtl3, Xtro\sfmbt2" "Mmus\L3mbtl1, Mmus\L3mbtl4, Mmus\Scml4, Mmus\Sfmbt1, Mmus\L3mbtl3, Mmus\Samd1, Mmus\Scml2, Mmus\Sfmbt2" "Hsap\L3MBTL4, Hsap\SAMD1, Hsap\SCML1, Hsap\L3MBTL3, Hsap\L3MBTL1, Hsap\SFMBT1, Hsap\SCML2, Hsap\THAP10, Hsap\SAMD13, Hsap\SCML4" " larval stage | third instar , larval stage | second instar , embryonic stage | >=0-3 hr , larval stage | first instar , embryonic stage | 0-3 hr , pupal stage , embryonic stage | stage 16 , embryonic stage | stage 16-17 , embryonic stage | 3-6 hr , adult stage | female , embryonic stage | stage 5 , embryonic stage | stage 1 , embryonic stage | stage 10 , larval stage&&pupal stage , larval stage && pupal stage , embryonic stage | stage 9 " " larval inner optic anlage

, larval brain

, subesophageal ganglion

, embryonic/larval foregut

, embryonic/larval hindgut

,

ubiquitous , imaginal disc

, ring gland

, embryonic/larval midgut

, procephalic neurogenic region

, lymph gland

, cephalic furrow

, muscle cell

, embryonic/larval fat body

, larval outer optic anlage

" "neuroanatomy defective,lethal,tumorigenic,recessive,wild-type,hyperplasia,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,maternal effect,female sterile,viable" "larval inner optic anlage,larval outer optic anlage,embryonic/larval brain,heat sensitive,neuroblast,ganglion mother cell,imaginal disc,wing disc,embryonic/larval optic lobe,ventral nerve cord,pole cell,germline clone,maternal effect,cleavage nucleus,ovary,germarium,egg" DRSC16983 EK 0.249292801 -0.021047596 1.368087409 -1.736603065 1.146873024 2.077337472 FBgn0040237 bor belphegor http://flybase.org/reports/FBgn0040237 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 - mitochondrion ; GO:0005739 | inferred from direct assay "CP89BC, CG6815, bor, ATAD3A, dATAD3A, Bor" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR021911:ATPase family AAA domain-containing protein 3, domain of unknown function DUF3523" CG6815 11-Aug-17 DroID_v2017_08 Drer\atad3b - Cele\atad-3 Xtro\atad3a Mmus\Atad3a "Hsap\ATAD3B, Hsap\ATAD3A, Hsap\ATAD3C" "female fertile,male sterile,meiotic cell cycle defective,visible,lethal - all die before end of pupal stage,some die during pupal stage,female semi-sterile" "centrosome, with asund93,spermatocyte,spermatid,trichogen cell" FBgn0015509 Cul1 Cullin 1 http://flybase.org/reports/FBgn0015509 "FBgn0020308, FBgn0022252" protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000231993 protein binding ; GO:0005515 | inferred from physical interaction with mi ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Roc1a "protein ubiquitination ; GO:0016567 | inferred by curator from GO:0019005,GO:0030163 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs neuron remodeling ; GO:0016322 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from genetic interaction with gig inferred from genetic interaction with Akt1 inferred from genetic interaction with Pi3K92E inferred from genetic interaction with Tor inferred from genetic interaction with Tsc1 inferred from genetic interaction with Pten inferred from genetic interaction with Thor inferred from genetic interaction with S6k protein ubiquitination ; GO:0016567 | inferred by curator from GO:0019005,GO:0031625 negative regulation of insulin receptor signaling pathway ; GO:0046627 | inferred from genetic interaction with InR regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein catabolic process ; GO:0030163 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000231993 negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype" SCF ubiquitin ligase complex ; GO:0019005 | non-traceable author statement SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Cul-1, CUL1, CG1877, cul1, Cul1, l(2)02074, cul-1, dCul1, lin19-like, dCul-1, l(2)k01207, lin-19/cul-1, dCUL1, lin 19, Lin19, Cullin1, Cul1[Ex], Cullin 1, dmCUL1, Q9V312, Lin-19, Cullin-1, lin19" "IPR001373:Cullin, N-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016157:Cullin, conserved site, IPR016158:Cullin homology, IPR016159:Cullin repeat-like-containing domain, IPR019559:Cullin protein, neddylation domain" CG1877 11-Aug-17 DroID_v2017_08 "Drer\cacul1, Drer\cul1a, Drer\cul1b" "Scer\RTT101, Scer\CDC53" "Cele\cul-6, Cele\cul-1" Xtro\cul1 "Mmus\Cacul1, Mmus\Cul1" "Hsap\CUL1, Hsap\CACUL1" "neuroanatomy defective,somatic clone,decreased cell death,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,visible,increased cell death,lethal,female sterile,germline clone" "dorsal multidendritic neuron ddaC,somatic clone,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaF,gamma Kenyon cell,alpha/beta Kenyon cell,dorsal multidendritic neuron ddaC | pupal stage,eye,wing,wing disc,eye disc,neuroblast,ovary,germline clone" DRSC07645 IK -0.297609348 1.528001415 -0.085725353 0.866010574 -0.692103751 2.337846572 FBgn0004244 Rdl Resistant to dieldrin http://flybase.org/reports/FBgn0004244 FBgn0010390 protein_coding_gene GABA-A receptor activity ; GO:0004890 | inferred from electronic annotation with InterPro:IPR002289 GABA-gated chloride ion channel activity ; GO:0022851 | inferred from direct assay GABA-A receptor activity ; GO:0004890 | traceable author statement neurotransmitter receptor activity ; GO:0030594 | inferred from direct assay inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with kcc sleep ; GO:0030431 | inferred from mutant phenotype negative regulation of synaptic transmission ; GO:0050805 | inferred from mutant phenotype regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype response to drug ; GO:0042493 | inferred from mutant phenotype ion transport ; GO:0006811 | inferred from direct assay regulation of circadian sleep/wake cycle ; GO:0042749 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201 integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity dendrite ; GO:0030425 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay" "Rdl, gaba, DmRdl, RDL, GABA[[A]] receptor, DmRDL, CG10537, GABA, LCCH1, GABA[[A]], GABAr, rdl, Rd1, CT29555, GABA[[A]]R, GABA-R, GABA[[A]]-R" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002289:Gamma-aminobutyric-acid A receptor, beta subunit, IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG10537 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-52k1.6, Drer\glra4b, Drer\gabrg2, Drer\gabrr2a, Drer\si:dkey-155h10.3, Drer\gabrb4, Drer\gabrr2b, Drer\zgc:110204, Drer\LOC100001259, Drer\LOC562831, Drer\gabrb2, Drer\glra4a, Drer\LOC561083, Drer\LOC100330554, Drer\glra3, Drer\gabrp, Drer\gabrb1, Drer\gabrb3, Drer\gabrr1, Drer\gabrr3a, Drer\glra1, Drer\gabrz, Drer\gabrd, Drer\gabra1, Drer\glrba, Drer\gabra5, Drer\gabra6a, Drer\gabra6b, Drer\glrbb, Drer\glra2" - "Cele\lgc-44, Cele\unc-49, Cele\ggr-1, Cele\lgc-40, Cele\lgc-41, Cele\avr-14, Cele\glc-4, Cele\glc-2, Cele\gab-1, Cele\lgc-42, Cele\lgc-36, Cele\lgc-35, Cele\avr-15, Cele\lgc-38, Cele\lgc-39, Cele\glc-1, Cele\exp-1, Cele\glc-3, Cele\lgc-37" "Xtro\glra2, Xtro\glra1, Xtro\glra3, Xtro\glrb, Xtro\gabrr3, Xtro\LOC100490720, Xtro\gabrd, Xtro\gabrp, Xtro\gabrg2, Xtro\gabra6, Xtro\gabra5, Xtro\gabra2, Xtro\gabrb3" "Mmus\Gabrp, Mmus\Gabrg1, Mmus\Gabrg3, Mmus\Glra4, Mmus\Gabra3, Mmus\Gabre, Mmus\Gabrb2, Mmus\Glrb, Mmus\Gabra6, Mmus\Gabra1, Mmus\Gabrb1, Mmus\Gabrg2, Mmus\Gabra2, Mmus\Gabrr3, Mmus\Glra1, Mmus\Gabra5, Mmus\Gabrd, Mmus\Gabrr1, Mmus\Glra3, Mmus\Gabrb3, Mmus\Gabrr2, Mmus\Gabrq, Mmus\Glra2" "Hsap\GLRA4, Hsap\GABRE, Hsap\GABRR3, Hsap\GABRB3, Hsap\GLRA1, Hsap\GABRA6, Hsap\GABRD, Hsap\GABRQ, Hsap\GABRG1, Hsap\GABRB1, Hsap\GABRA1, Hsap\GABRB2, Hsap\GABRA5, Hsap\GABRG3, Hsap\GABRR2, Hsap\GLRA2, Hsap\GABRR1, Hsap\GLRA3, Hsap\GABRA4, Hsap\GLRB, Hsap\GABRP, Hsap\GABRA2, Hsap\GABRG2" adult stage adult head

"lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,chemical resistant,heat stress response defective,wild-type,chemical sensitive,dominant,some die during immature adult stage,semidominant,behavior defective,heat sensitive,male sterile,viable,learning defective,circadian behavior defective,neuroanatomy defective" "VUM neuron,aCC neuron,RP2 motor neuron,intersegmental nerve,abdominal intersegmental nerve,mesothoracic intersegmental nerve,metathoracic intersegmental nerve,prothoracic intersegmental nerve,U neuron" FBgn0001565 Hlc Helicase http://flybase.org/reports/FBgn0001565 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000004266 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000618724 neurogenesis ; GO:0022008 | inferred from mutant phenotype RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "HLC, DmRH10, hlc, A112, l(1)A112, HM-44, 11P1, l(1)11P1, lA112, l11P1, 14, 7, l(1)S-19F6, l(1)8-1, l(1)19Ff, CG1666, Hlc" "IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1666 11-Aug-17 DroID_v2017_08 Drer\ddx56 Scer\DBP9 Cele\C24H12.4 Xtro\ddx56 Mmus\Ddx56 Hsap\DDX56 " larval stage , adult stage && oogenesis stage , embryonic stage -- adult stage , adult stage , pupal stage | late " " embryonic/larval fat body

, ovary

, larval brain

, imaginal disc

, embryonic/larval salivary gland

, adult brain

, brain

" "viable,fertile,wild-type,lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "central nervous system,peripheral nervous system,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0029925 CG3040 - http://flybase.org/reports/FBgn0029925 protein_coding_gene - - - "CT9706, CG3040" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG3040 11-Aug-17 DroID_v2017_08 "Drer\rxfp2a, Drer\lrrc57, Drer\rxfp2l" Scer\SOG2 Cele\ZK546.2 Xtro\lrrc57 "Mmus\Lrrc57, Mmus\Rxfp1, Mmus\Rxfp2" "Hsap\RXFP1, Hsap\RXFP2, Hsap\LRRC57" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0034258 eIF3c eukaryotic translation initiation factor 3 subunit c http://flybase.org/reports/FBgn0034258 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000358559 translation initiation factor binding ; GO:0031369 | inferred from biological aspect of ancestor with PANTHER:PTN000358559 translational initiation ; GO:0006413 | inferred from biological aspect of ancestor with PANTHER:PTN000358559 translational initiation ; GO:0006413 | inferred from sequence or structural similarity eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from sequence or structural similarity mitochondrion ; GO:0005739 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000358559 "CG4954, eIF3-s8, eIF3-S8, eIF3c" "IPR000717:Proteasome component (PCI) domain, IPR008905:Eukaryotic translation initiation factor 3 subunit C, N-terminal domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR027516:Eukaryotic translation initiation factor 3 subunit C" CG4954 11-Aug-17 DroID_v2017_08 Drer\eif3c Scer\NIP1 "Cele\ZC443.3, Cele\eif-3.C" Xtro\eif3c Mmus\Eif3c "Hsap\EIF3CL, Hsap\EIF3C" "lethal,recessive" DRSC06905 IE -2.087736444 -0.950672904 -3.280064155 -3.808465902 0.154091937 1.027664046 FBgn0020440 Fak Focal adhesion kinase http://flybase.org/reports/FBgn0020440 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR005189 non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 signal complex assembly ; GO:0007172 | inferred from electronic annotation with InterPro:IPR005189 negative regulation of MAP kinase activity ; GO:0043407 | inferred from genetic interaction with Ret cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Egfr cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 focal adhesion ; GO:0005925 | inferred from sequence or structural similarity type Ib terminal bouton ; GO:0061176 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 focal adhesion ; GO:0005925 | inferred from direct assay type Is terminal bouton ; GO:0061177 | inferred from direct assay "Fak56, Fak, FAK, DFak, DFAK, CG10023, CT28129, DFak56, Dfak, Dfak56, DmFAK, fak, fak56, FAK65D, Fak56D, ptk2, dFak, pFAK" "IPR000299:FERM domain, IPR000719:Protein kinase domain, IPR005189:Focal adhesion kinase, targeting (FAT) domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR011993:PH domain-like, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR029071:Ubiquitin-related domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG10023 11-Aug-17 DroID_v2017_08 "Drer\ptk2aa, Drer\ptk2ab, Drer\ptk2ba, Drer\ptk2bb" Scer\KIN1 "Cele\kin-32, Cele\cdk-4" "Xtro\ptk2, Xtro\ptk2b" "Mmus\Ptk2b, Mmus\Ptk2" "Hsap\PTK2, Hsap\PTK2B" " embryonic stage -- adult stage , embryonic stage | stage 16 , embryonic stage | stage >=14 , embryonic stage && larval stage , embryonic stage , embryonic stage | stage 13 " " muscle attachment site

, embryonic brain

, organism

,

ubiquitous , embryonic central nervous system

, midgut primordium

" " adult stage && oogenesis stage | stage S9 , embryonic stage -- adult stage , embryonic stage , pupal stage | early , embryonic stage | stage >=13 , embryonic stage | stage 16 , adult stage && oogenesis stage | stage S1-6 , adult stage && oogenesis stage " " border follicle cell

, embryonic central nervous system

, ovarian sheath cell

, muscle attachment site

, egg chamber

,

ubiquitous , follicle cell

, embryonic/larval midgut

" "neuroanatomy defective,viable,fertile,neurophysiology defective,visible,female" "neuromuscular junction | third instar larval stageelav.PU,NMJ bouton,supernumerary | third instar larval stage,axon & eye photoreceptor cell,embryonic/larval optic stalk,subretinal glial cell,synapse,bouton,neuromuscular junction | third instar larval stage,wing,female,posterior,muscle attachment site | embryonic stage,medial longitudinal fascicle | embryonic stage,lateral longitudinal fascicle | embryonic stage,supernumerary" FBgn0016690 Opl Opthalmopedia-like http://flybase.org/reports/FBgn0016690 - gene molecular_function ; GO:0003674 | no biological data available eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Opl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "retina,rhabdomere" FBgn0063777 vacu vacuous http://flybase.org/reports/FBgn0063777 gene - central nervous system development ; GO:0007417 | inferred from mutant phenotype - "ND12, vacu" - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,heat sensitive,short lived,neurophysiology defective,locomotor behavior defective,flight defective" "central nervous system,optic lobe,thoracico-abdominal ganglion,brain" FBgn0011836 Taf2 TBP-associated factor 2 http://flybase.org/reports/FBgn0011836 - protein_coding_gene "metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR014782 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR014782 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000388531 transcription regulatory region DNA binding ; GO:0044212 | contributes_to inferred from direct assay transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf11 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000388531 transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf1 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly ; GO:0001129 | inferred from physical interaction with Tbp" "RNA polymerase II transcriptional preinitiation complex assembly ; GO:0051123 | inferred from direct assay positive regulation of transcription of Notch receptor target ; GO:0007221 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11536 inferred from sequence or structural similarity with SGD:S000000638 positive regulation of transcription initiation from RNA polymerase II promoter ; GO:0060261 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA-templated transcription, initiation ; GO:0006352 | inferred from direct assay" transcription factor TFIID complex ; GO:0005669 | inferred from physical interaction with Taf1 transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11536 inferred from sequence or structural similarity with SGD:S000000638 nucleus ; GO:0005634 | inferred from direct assay "dTAF[[II]]150, TAF150, TAF, TFIID, TAF[[II]], Taf150, TAF[II]150, TAF[[II]]150, TAF2, dTAFII150, dTAF150, TAFII150, CG6711, dTAF II 150, TafII150, Taf[[II]]150, Taf2, taf2" "IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG6711 11-Aug-17 DroID_v2017_08 Drer\taf2 Scer\TAF2 Cele\taf-2 Xtro\taf2 Mmus\Taf2 Hsap\TAF2 "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,female sterile" "embryonic/larval neuroblast,ganglion mother cell" DRSC11298 IEK -1.896211508 1.472208839 -1.587347023 0.243070858 1.335717424 1.797060189 FBgn0263251 vnc variable nurse cells http://flybase.org/reports/FBgn0263251 protein_coding_gene peptide-glutamate-N-acetyltransferase activity ; GO:1990190 | inferred from biological aspect of ancestor with PANTHER:PTN000558281 peptide-serine-N-acetyltransferase activity ; GO:1990189 | inferred from biological aspect of ancestor with PANTHER:PTN000558281 N-terminal peptidyl-serine acetylation ; GO:0017198 | inferred from biological aspect of ancestor with PANTHER:PTN000558281 neurogenesis ; GO:0022008 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype N-terminal peptidyl-glutamic acid acetylation ; GO:0018002 | inferred from biological aspect of ancestor with PANTHER:PTN000558281 histone acetylation ; GO:0016573 | inferred from mutant phenotype NatA complex ; GO:0031415 | inferred from biological aspect of ancestor with PANTHER:PTN000558281 NatA complex ; GO:0031415 | inferred from direct assay protein acetyltransferase complex ; GO:0031248 | inferred from physical interaction with UniProtKB:Q9NHD5 cytosolic ribosome ; GO:0022626 | inferred from biological aspect of ancestor with PANTHER:PTN000558281 "Ard1, vnc, ard1, l(3)67BDk, CG11989, ARD1, dArd1, DmAAF50178, Dromel_CG11989_FBtr0076348_ard1_mORF, NAA10, Naa10, dNaa10, Naa10/11" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG11989 11-Aug-17 DroID_v2017_08 Drer\naa10 Scer\ARD1 Cele\daf-31 Xtro\naa10 "Mmus\Txnl4a, Mmus\Naa10, Mmus\Naa11" "Hsap\NAA10, Hsap\NAA11" DRSC09867 I 0.354908156 1.615056328 0.90515488 0.742195521 -0.302816717 1.291736301 FBgn0250746 Prosbeta7 Proteasome beta7 subunit http://flybase.org/reports/FBgn0250746 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR016295, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" "proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR016050 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839" proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay "CG12000, beta-4, 154275_at, GC12000, anon-WO0118547.326, 12000, Prosbeta7, Prosbeta4, Beta-7, beta7, Prot. beta4, beta-7" "IPR001353:Proteasome, subunit alpha/beta, IPR023333:Proteasome B-type subunit, IPR016050:Proteasome beta-type subunit, conserved site, IPR016295:Proteasome endopeptidase complex, beta subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG12000 11-Aug-17 DroID_v2017_08 Drer\psmb4 Scer\PRE4 Cele\pbs-7 Xtro\psmb4 Mmus\Psmb4 Hsap\PSMB4 DRSC12186 IEK -1.783588051 -3.804350521 -1.529653384 -1.839486055 1.916898999 0.446617913 FBgn0035510 Cpr64Aa Cuticular protein 64Aa http://flybase.org/reports/FBgn0035510 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr64Aa, CG15006, DmelCpr64Aa" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG15006 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable DRSC08460 E -1.310413269 -0.426565918 -1.598642077 0.42905313 0.578638093 0.58421029 FBgn0037149 CG14561 - http://flybase.org/reports/FBgn0037149 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14561 - CG14561 11-Aug-17 DroID_v2017_08 - - - - - - DRSC11722 K 0.242298741 0.47774807 -0.773237905 0.277628679 1.509449882 -0.020575639 FBgn0050441 CG30441 - http://flybase.org/reports/FBgn0050441 protein_coding_gene molecular_function ; GO:0003674 | no biological data available intraciliary transport ; GO:0042073 | inferred from biological aspect of ancestor with PANTHER:PTN001278111 centrosome localization ; GO:0051642 | inferred from biological aspect of ancestor with PANTHER:PTN001278111 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN001278111 cilium assembly ; GO:0060271 | inferred from sequence model protein localization to cilium ; GO:0061512 | inferred from biological aspect of ancestor with PANTHER:PTN001278111 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN001278111 cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN001278111 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN001278111 cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:1915585 intraciliary transport particle B ; GO:0030992 | inferred from biological aspect of ancestor with PANTHER:PTN001278111 intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:1915585 "CG30441, IFT20" IPR028172:Intraflagellar transport protein 20 CG30441 11-Aug-17 DroID_v2017_08 Drer\ift20 - Cele\ift-20 Xtro\ift20 Mmus\Ift20 Hsap\IFT20 viable DRSC22660 E 1.102991943 0.397278837 0.142389746 1.898136379 -0.87807626 -1.153295885 FBgn0039773 CG2224 - http://flybase.org/reports/FBgn0039773 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:16950 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:16950 cellular_component ; GO:0005575 | no biological data available "CG2224, Amsh, Q9VA71, AMSH" "IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR015063:USP8 dimerisation domain" CG2224 11-Aug-17 DroID_v2017_08 "Drer\stambpl1, Drer\stambpa, Drer\stambpb" Scer\RFU1 Cele\Y76B12C.6 "Xtro\stambpl1, Xtro\stambp" "Mmus\Stambpl1, Mmus\Stambp" "Hsap\STAMBP, Hsap\STAMBPL1" "viable,locomotor behavior defective" DRSC24269 K 0.125453121 -0.520729184 -0.687133403 -0.295994943 -1.688873431 -0.897009077 FBgn0030141 Gga "Golgi-localized, gamma-adaptin ear containing, ARF binding protein" http://flybase.org/reports/FBgn0030141 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Lerp protein transporter activity ; GO:0008565 | inferred from mutant phenotype clathrin heavy chain binding ; GO:0032050 | inferred from physical interaction with Chc "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002014, InterPro:IPR004152, InterPro:IPR008152 vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype post-Golgi vesicle-mediated transport ; GO:0006892 | inferred from mutant phenotype post-Golgi vesicle-mediated transport ; GO:0006892 | inferred from sequence or structural similarity with UniProt:Q9NZ52,UniProt:Q9UJY4,UniProtKB:Q9UJY5" clathrin adaptor complex ; GO:0030131 | inferred from electronic annotation with InterPro:IPR008152 cytosol ; GO:0005829 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay clathrin-coated vesicle ; GO:0030136 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from direct assay cytoplasm ; GO:0005737 | inferred by curator from GO:0006892 "CG3002, GGA, dmGGA, Gga, dGGA, DmGGA1" "IPR002014:VHS domain, IPR004152:GAT domain, IPR008152:Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain, IPR008153:Gamma-adaptin ear (GAE) domain, IPR008942:ENTH/VHS, IPR013041:Coatomer/clathrin adaptor appendage, Ig-like subdomain" CG3002 11-Aug-17 DroID_v2017_08 "Drer\gga1, Drer\tom1, Drer\si:ch73-157i16.3, Drer\tom1l2, Drer\gga3" "Scer\GGA2, Scer\LSB5, Scer\GGA1" "Cele\apt-9, Cele\C07A12.7" "Xtro\tom1l1, Xtro\tom1l2, Xtro\tom1, Xtro\gga1, Xtro\gga3" "Mmus\Tom1l2, Mmus\Tom1, Mmus\Gga1, Mmus\Gga2, Mmus\Gga3, Mmus\Tom1l1" "Hsap\TOM1L2, Hsap\GGA3, Hsap\GGA1, Hsap\TOM1L1, Hsap\GGA2, Hsap\TOM1" "viable,fertile,chemical sensitive,starvation stress response defective,partially lethal - majority die,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,neuroanatomy defective,progressive,visible,size defective,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere R7,retina,photoreceptor cell,cell body rind of lamina,vacuoleGMR.PF,eye photoreceptor cell,rhabdomere of eye photoreceptor cell,pigment granuleGMR.PF, ey.PH,progressive,eye,interommatidial bristle" FBgn0070049 3L-200-14 3L-200-14 http://flybase.org/reports/FBgn0070049 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3L-200-14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect" FBgn0036727 CG7589 - http://flybase.org/reports/FBgn0036727 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 chloride channel activity ; GO:0005254 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001055382 "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006029, InterPro:IPR006201 phagocytosis ; GO:0006909 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201" "CG7589, Lcch-74C, CT23187" "IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000:Neurotransmitter-gated ion-channel, conserved site" CG7589 11-Aug-17 DroID_v2017_08 "Drer\glra1, Drer\glra3, Drer\glra4b, Drer\glra4a, Drer\glrba, Drer\glra2, Drer\glrbb" - "Cele\ggr-3, Cele\lgc-53, Cele\lgc-48, Cele\lgc-49, Cele\acc-4, Cele\acc-3, Cele\acc-1, Cele\lgc-55, Cele\glc-4, Cele\lgc-50, Cele\lgc-52, Cele\avr-15, Cele\lgc-51, Cele\glc-1, Cele\avr-14, Cele\acc-2, Cele\lgc-46, Cele\lgc-54, Cele\mod-1, Cele\lgc-47, Cele\glc-3, Cele\glc-2" "Xtro\glra1, Xtro\glra2, Xtro\glra3, Xtro\glrb" "Mmus\Glra1, Mmus\Glra3, Mmus\Gabrb3, Mmus\Glrb, Mmus\Glra2, Mmus\Glra4" "Hsap\GLRA1, Hsap\GLRA3, Hsap\GABRB3, Hsap\GLRA4, Hsap\GLRA2, Hsap\GLRB" "viable,lethal" DRSC10887 K -0.222288924 -0.172182367 -0.021731693 0.189480702 1.662892238 -1.225848599 FBgn0030864 CG8173 - http://flybase.org/reports/FBgn0030864 protein_coding_gene protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR034368 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 "mitotic nuclear division ; GO:0007067 | inferred from electronic annotation with InterPro:IPR034368 protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271" cellular_component ; GO:0005575 | no biological data available CG8173 "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR034368:Lymphokine-activated killer T-cell-originated protein kinase" CG8173 11-Aug-17 DroID_v2017_08 "Drer\mos, Drer\LOC405768, Drer\lrrk2, Drer\zak, Drer\map3k9, Drer\ripk1l, Drer\ripk2, Drer\map3k10, Drer\ripk4, Drer\pbk, Drer\dstyk, Drer\si:ch211-120p12.3, Drer\ripk3" - Cele\ZC581.7 "Xtro\dstyk, Xtro\map3k7, Xtro\lrrk2, Xtro\LOC100490493, Xtro\mlkl, Xtro\pbk, Xtro\lrrk1, Xtro\ripk1, Xtro\zak, Xtro\map3k9, Xtro\map3k10, Xtro\ripk4, Xtro\ankk1" "Mmus\Ripk2, Mmus\Lrrk1, Mmus\BC021891, Mmus\Zak, Mmus\Mos, Mmus\Map3k7, Mmus\Ripk3, Mmus\Dstyk, Mmus\Map3k9, Mmus\Map3k11, Mmus\Ripk1, Mmus\Pbk, Mmus\Map3k10, Mmus\Lrrk2, Mmus\Mlkl, Mmus\Ripk4" "Hsap\DSTYK, Hsap\LRRK1, Hsap\MAP3K21, Hsap\MAP3K20, Hsap\LRRK2, Hsap\MOS, Hsap\RIPK1, Hsap\RIPK4, Hsap\MAP3K11, Hsap\MLKL, Hsap\MAP3K7, Hsap\RIPK2, Hsap\MAP3K10, Hsap\RIPK3, Hsap\MAP3K9, Hsap\PBK" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0016926 Pino Pinocchio http://flybase.org/reports/FBgn0016926 "FBgn0031303, FBgn0062225" protein_coding_gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok - "CG4710, anon-WO0118547.131, Pino, smi21F" - CG4710 11-Aug-17 DroID_v2017_08 - - - - - - "viable,neurophysiology defective,smell perception defective,behavior defective,recessive,male,female,fertile" antenna DRSC00662 E -0.019324024 -0.781028941 1.098479244 -2.74748845 -1.029107647 0.344127355 FBgn0060431 l(3)S125816b lethal (3) S125816b http://flybase.org/reports/FBgn0060431 gene - - - l(3)S125816b - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0005133 l(1)Y12 lethal (1) Y12 http://flybase.org/reports/FBgn0005133 - gene - - - l(1)Y12 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal - all die before end of embryonic stage,some die during embryonic stage" wing FBgn0036298 nst nesthocker http://flybase.org/reports/FBgn0036298 protein_coding_gene phosphoacetylglucosamine mutase activity ; GO:0004610 | inferred from electronic annotation with InterPro:IPR016657 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR016066 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR005844, InterPro:IPR016055 mesoderm formation ; GO:0001707 | inferred from mutant phenotype positive regulation of fibroblast growth factor receptor signaling pathway ; GO:0045743 | inferred from mutant phenotype inferred from genetic interaction with htl trachea development ; GO:0060438 | inferred from mutant phenotype UDP-N-acetylglucosamine biosynthetic process ; GO:0006048 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000501326 "CG10627, nst" "IPR005843:Alpha-D-phosphohexomutase, C-terminal, IPR005844:Alpha-D-phosphohexomutase, alpha/beta/alpha domain I, IPR016055:Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III, IPR016066:Alpha-D-phosphohexomutase, conserved site, IPR016657:Phosphoacetylglucosamine mutase" CG10627 11-Aug-17 DroID_v2017_08 Drer\pgm3 Scer\PCM1 Cele\F21D5.1 Xtro\pgm3 Mmus\Pgm3 Hsap\PGM3 "lethal,viable" "mesoderm,germline clone,embryonic/larval dorsal trunk" FBgn0004478 l(1)air2 lethal aberrant immune response 2 http://flybase.org/reports/FBgn0004478 - gene - - - "air2, l(1)air2" - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "embryonic/larval brain,embryonic/larval lymph gland,melanotic mass" FBgn0037917 wkd whacked http://flybase.org/reports/FBgn0037917 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 "regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561" filopodium ; GO:0030175 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 "CG5344, wkd, cg5344, Wkd" IPR000195:Rab-GTPase-TBC domain CG5344 11-Aug-17 DroID_v2017_08 "Drer\tbc1d10aa, Drer\tbc1d10ab, Drer\si:ch211-266k8.4, Drer\grtp1a, Drer\tbc1d9, Drer\sgsm3, Drer\tbc1d10c, Drer\si:dkey-110k5.6" "Scer\MDR1, Scer\GYL1, Scer\MSB3, Scer\MSB4" "Cele\tbc-9, Cele\tbc-6, Cele\tbc-10, Cele\tbc-18" "Xtro\grtp1, Xtro\tbc1d10b, Xtro\tbc1d10a" "Mmus\Sgsm3, Mmus\Tbc1d10b, Mmus\Tbc1d10a, Mmus\Tbc1d8b, Mmus\Tbc1d10c, Mmus\Grtp1, Mmus\Tbc1d9b, Mmus\Tbc1d9, Mmus\Tbc1d8" "Hsap\TBC1D10B, Hsap\GATSL3, Hsap\TBC1D10A, Hsap\TBC1D9, Hsap\GRTP1, Hsap\TBC1D9B, Hsap\SGSM3, Hsap\TBC1D8, Hsap\TBC1D10C, Hsap\TBC1D8B" "lethal,viable,lethal - all die before end of P-stage,some die during pharate adult stage" "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,tracheal fusion cell" DRSC15777 K 0.629129246 0.312149591 0.370484696 0.653728399 1.575268059 -1.403527005 FBgn0028189 l(3)S023549 lethal (3) S023549 http://flybase.org/reports/FBgn0028189 gene - - - "l(3)S090101, 0901/01, 0235/49, l(3)S023549" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0061043 l(3)S023723 lethal (3) S023723 http://flybase.org/reports/FBgn0061043 gene - - - "0237/23, l(3)S023723" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003462 Sod1 Superoxide dismutase 1 http://flybase.org/reports/FBgn0003462 - protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Sod1 superoxide dismutase activity ; GO:0004784 | inferred from mutant phenotype antioxidant activity ; GO:0016209 | non-traceable author statement copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001424, InterPro:IPR018152 superoxide metabolic process ; GO:0006801 | inferred from electronic annotation with InterPro:IPR001424 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | traceable author statement regulation of mitophagy ; GO:1903146 | inferred from genetic interaction with park aging ; GO:0007568 | traceable author statement determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype age-dependent response to oxidative stress ; GO:0001306 | inferred from mutant phenotype" peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:11179 inferred from sequence model inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "SOD, Cu/Zn sod, CuZnSOD, Sod-1, sod1, Sod1, CuZn-SOD, Cu,Zn-SOD, cSOD, sod, Cu[2+]/Zn[2+]SOD, Cu/Zn superoxide dismutase, Cu/Zn SOD, To-1, Cu/ZnSOD, SOD1, Cu-Zn SOD, CuZn SOD, cSod, Cu,Zn Sod, l(3)68Af', SOD-1, l(3)G, l(3)108, To, G, CG11793, CuSOD, Sod, Mn SOD, ZnSod, CuZn-SOD1, dSOD1, Cu,Zn SOD, SODC_DROME" "IPR018152:Superoxide dismutase, copper/zinc, binding site, IPR001424:Superoxide dismutase, copper/zinc binding domain" CG11793 11-Aug-17 DroID_v2017_08 "Drer\sod3b, Drer\sod3a, Drer\sod1" "Scer\CCS1, Scer\SOD1" "Cele\sod-1, Cele\sod-5, Cele\sod-4" "Xtro\sod1, Xtro\sod3" "Mmus\Sod3, Mmus\Sod1" "Hsap\SOD3, Hsap\SOD1" "viable,chemical sensitive,oxidative stress response defective,male sterile,lethal,recessive,female fertile,reduced,short lived,radiation sensitive,partially,heat sensitive,visible,long lived,chemical conditional,behavior defective,wild-type,electrophoretic variant,partially lethal - majority die,female limited,male limited,calorie restriction conditional,locomotor behavior defective" "adult heart,photoreceptor cell,primary pigment cell,secondary pigment cell,adult brain,trichogen cell" FBgn0053885 His4:CG33885 His4:CG33885 http://flybase.org/reports/FBgn0053885 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33885, His4:CG33885" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33885 11-Aug-17 DroID_v2017_08 "Drer\LOC570405, Drer\zgc:163040, Drer\si:ch73-368j24.1, Drer\hist1h4l, Drer\si:dkey-108k21.28, Drer\si:ch73-36p18.3, Drer\LOC100329358, Drer\zgc:194989, Drer\si:dkey-108k21.19, Drer\si:dkey-261m9.17, Drer\LOC100331412, Drer\si:ch211-113a14.6, Drer\si:ch73-368j24.14, Drer\LOC562770, Drer\si:dkey-261m9.18, Drer\zgc:154164, Drer\si:ch73-36p18.4, Drer\LOC794549, Drer\si:ch211-113a14.17, Drer\zgc:153409, Drer\si:dkey-23a13.7, Drer\LOC100150038, Drer\si:ch211-113a14.26, Drer\si:dkey-108k21.12" "Scer\HHF2, Scer\HHF1" "Cele\his-10, Cele\his-1, Cele\his-50, Cele\his-37, Cele\his-64, Cele\his-60, Cele\his-18, Cele\his-31, Cele\his-67, Cele\his-38, Cele\his-46, Cele\his-56, Cele\his-5, Cele\his-28, Cele\his-14, Cele\his-26" "Xtro\hist1h4c, Xtro\LOC100493041, Xtro\hist1h4k" "Mmus\Hist1h4n, Mmus\Hist1h4i, Mmus\Hist1h4h, Mmus\Hist1h4b, Mmus\Hist1h4a, Mmus\Hist4h4, Mmus\Hist1h4m, Mmus\Hist2h4, Mmus\Hist1h4j, Mmus\Hist1h4d, Mmus\Hist1h4f, Mmus\Hist1h4k, Mmus\Hist1h4c" "Hsap\HIST2H4B, Hsap\HIST1H4D, Hsap\HIST1H4F, Hsap\HIST1H4I, Hsap\HIST4H4, Hsap\HIST1H4H, Hsap\HIST2H4A, Hsap\HIST1H4C, Hsap\HIST1H4J, Hsap\HIST1H4L, Hsap\HIST1H4E, Hsap\HIST1H4G, Hsap\HIST1H4K, Hsap\HIST1H4B, Hsap\HIST1H4A" FBgn0031866 Nlg2 Neuroligin 2 http://flybase.org/reports/FBgn0031866 protein_coding_gene receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O61307 carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 neurexin family protein binding ; GO:0042043 | inferred from physical interaction with Nrx-1 "inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 social behavior ; GO:0035176 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype male courtship behavior, veined wing extension ; GO:0048065 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 maintenance of presynaptic active zone structure ; GO:0048790 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype synaptic vesicle membrane organization ; GO:0048499 | inferred from mutant phenotype synapse maturation ; GO:0060074 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype negative regulation of synaptic transmission ; GO:0050805 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype" neuromuscular junction ; GO:0031594 | inferred from direct assay cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 postsynaptic membrane ; GO:0045211 | inferred from direct assay "CG13772, dnl2, nl2, Nlg2, neuroligin, dnlg2, DNlg2, nlg2" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR029058:Alpha/Beta hydrolase fold" CG13772 11-Aug-17 DroID_v2017_08 "Drer\nlgn1, Drer\nlgn2b, Drer\nlgn3a, Drer\ces2, Drer\nlgn4a, Drer\cel.1, Drer\cell, Drer\nlgn3b, Drer\si:ch211-93f2.1, Drer\nlgn4b, Drer\nlgn2a, Drer\ces3" - "Cele\W02B12.4, Cele\nlg-1, Cele\T02B5.1, Cele\ZC376.3, Cele\T02B5.3, Cele\ZK994.1, Cele\ZC376.2, Cele\glit-1, Cele\Y75B8A.3, Cele\ZC376.1" "Xtro\nlgn4x, Xtro\cel, Xtro\LOC100494782, Xtro\ces2, Xtro\ces3, Xtro\nlgn2, Xtro\nlgn3" "Mmus\Ces2f, Mmus\Ces5a, Mmus\Ces3a, Mmus\Ces2h, Mmus\Ces1h, Mmus\Ces1b, Mmus\Ces1e, Mmus\Nlgn2, Mmus\Ces1d, Mmus\Nlgn1, Mmus\Ces4a, Mmus\Cel, Mmus\Ces2g, Mmus\Ces2e, Mmus\Ces1f, Mmus\Ces1g, Mmus\Ces1c, Mmus\Ces2a, Mmus\Ces3b, Mmus\Nlgn3, Mmus\Ces2c, Mmus\Ces2b" "Hsap\CES1, Hsap\NLGN4Y, Hsap\CES4A, Hsap\NLGN1, Hsap\NLGN3, Hsap\NLGN2, Hsap\CES2, Hsap\CES5A, Hsap\NLGN4X, Hsap\CEL, Hsap\CES3" "viable,neuroanatomy defective,neurophysiology defective,fertile,locomotor behavior defective,song defective,behavior defective,courtship behavior defective,male" "embryonic/larval neuromuscular junction,NMJ bouton,presynaptic active zone | supernumerary,subsynaptic reticulum,postsynaptic density,bouton,t-bar,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage,supernumerary | third instar larval stage,synapse | embryonic stage,synapse | larval stage" DRSC03578 IE 1.903573478 -0.243028619 1.739972964 0.428813502 -0.059217772 -0.539347002 FBgn0024208 obk obake http://flybase.org/reports/FBgn0024208 - gene molecular_function ; GO:0003674 | no biological data available eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available obk - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive" "antenna,second segment of antenna,supernumerary,third segment of antenna,arista,maxillary segment,eye,head & macrochaeta,maxillary palpus,wing vein" FBgn0035917 Zasp66 Z band alternatively spliced PDZ-motif protein 66 http://flybase.org/reports/FBgn0035917 protein_coding_gene muscle alpha-actinin binding ; GO:0051371 | inferred from physical interaction with Actn protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B myofibril assembly ; GO:0030239 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern Z disc ; GO:0030018 | inferred from direct assay "anon-WO0153538.30, Zaps66, CG6416, Zasp66, ZASP66" "IPR001478:PDZ domain, IPR006643:Zasp-like motif, IPR017351:LIM and senescent cell antigen-like-containing domain protein 1, IPR031847:Domain of unknown function DUF4749" CG6416 11-Aug-17 DroID_v2017_08 "Drer\gsc, Drer\dmbx1b, Drer\pdlim4, Drer\pdlim2, Drer\lims2, Drer\shox2, Drer\shox, Drer\pax6b, Drer\mxtx2, Drer\lims1, Drer\pdlim7, Drer\hoxb8a, Drer\pitx1, Drer\pax6a, Drer\lhx6, Drer\pdlim3b, Drer\dmbx1a, Drer\ldb3a, Drer\pitx3, Drer\ldb3b" "Scer\YHP1, Scer\PHO2, Scer\PXL1" "Cele\ceh-45, Cele\ceh-51, Cele\unc-97, Cele\alp-1, Cele\pin-2, Cele\lim-4, Cele\vab-3" "Xtro\shox2, Xtro\pitx1, Xtro\gsc, Xtro\pitx3, Xtro\hoxb8, Xtro\pdlim5, Xtro\lhx8" "Mmus\Lims2, Mmus\Pdlim7, Mmus\Gsc, Mmus\Pitx3, Mmus\Pitx1, Mmus\Lhx8, Mmus\Shox2, Mmus\Pdlim5, Mmus\Pdlim2, Mmus\Lims1, Mmus\Dmbx1, Mmus\Pdlim3, Mmus\Pdlim1, Mmus\Lhx6, Mmus\Pdlim4, Mmus\Ldb3, Mmus\Gsc2, Mmus\Pax6" "Hsap\LPXN, Hsap\PITX3, Hsap\LIMS3, Hsap\LIMS2, Hsap\PDLIM1, Hsap\LDB3, Hsap\HOXB8, Hsap\DMBX1, Hsap\GSC, Hsap\PITX1, Hsap\PDLIM3, Hsap\PDLIM4, Hsap\LHX6, Hsap\LIMS1, Hsap\PDLIM5, Hsap\PDLIM2, Hsap\LHX8, Hsap\GSC2, Hsap\SHOX2, Hsap\PDLIM7, Hsap\PAX6, Hsap\LIMS4, Hsap\SHOX" "viable,fertile,lethal,flightless,majority die during pupal stage,partially lethal" "indirect flight muscle,myofibril, with Dcr-2UAS.cDa, Mef2.PR,Z disc, with Dcr-2UAS.cDa, Mef2.PR,M band, with Dcr-2UAS.cDa, Mef2.PR,Z discMef2.PR" FBgn0000119 arr arrow http://flybase.org/reports/FBgn0000119 "FBgn0022055, FBgn0025707, FBgn0033841, FBgn0040307" protein_coding_gene Wnt-activated receptor activity ; GO:0042813 | inferred from direct assay Wnt-protein binding ; GO:0017147 | inferred from physical interaction with wg low-density lipoprotein receptor activity ; GO:0005041 | inferred from sequence or structural similarity with MGI:MGI:1278315 inferred from sequence or structural similarity with MGI:MGI:1298218 long-term memory ; GO:0007616 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype protein targeting to lysosome ; GO:0006622 | inferred from mutant phenotype regulation of compound eye pigmentation ; GO:0048076 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype canonical Wnt signaling pathway ; GO:0060070 | inferred from mutant phenotype late endosome ; GO:0005770 | colocalizes_with inferred from direct assay early endosome ; GO:0005769 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "LRP/Arr, LRP, CG5912, LRP5/6, CT15575, LRP6, CK00539, l(2)k08131, BEST:CK00539, arr, Irp6, Arr, Dm Arr" "IPR000033:LDLR class B repeat, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR017049:Low density lipoprotein receptor-related protein 5/6, IPR000742:EGF-like domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG5912 11-Aug-17 DroID_v2017_08 "Drer\lrp1ab, Drer\ap2m1a, Drer\lrp5, Drer\lrp1ba, Drer\ap2m1b, Drer\lrp6, Drer\lrp1bb, Drer\lrp2a" - "Cele\lrp-1, Cele\lrp-2, Cele\dpy-23, Cele\ZC101.1" "Xtro\lrp5, Xtro\lrp4, Xtro\lrp6" "Mmus\Lrp4, Mmus\Lrp1, Mmus\Lrp6, Mmus\Lrp1b, Mmus\Lrp2, Mmus\Ap2m1, Mmus\Lrp5" "Hsap\LRP5L, Hsap\LRP5, Hsap\LRP6, Hsap\LRP1, Hsap\AP2M1, Hsap\LRP2, Hsap\LRP4, Hsap\LRP1B" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,cell lethal,partially,somatic clone,planar polarity defective,visible,cell non-autonomous,increased cell death,cell growth defective,viable,memory defective,RU486 conditional,partially lethal - majority die,some die during pupal stage" "macrochaeta,midgut constriction 2,gastric caecum,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,eye,head,cuticle,photoreceptor cell,somatic clone,eye disc,embryonic/first instar larval cuticle,denticle,embryonic epidermis,ommatidium,denticle belt,wing,wing margin bristle,ectopic,interommatidial bristle,maternal effect,retina,wing disc,secondary pigment cell,tertiary pigment cell,wing sensillum" FBgn0040623 Spase12 Spase 12-subunit http://flybase.org/reports/FBgn0040623 protein_coding_gene peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR009542 protein targeting to ER ; GO:0045047 | inferred from biological aspect of ancestor with PANTHER:PTN000324614 signal peptide processing ; GO:0006465 | inferred from biological aspect of ancestor with PANTHER:PTN000324614 signal peptidase complex ; GO:0005787 | inferred from biological aspect of ancestor with PANTHER:PTN000324614 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000324614 "CG11500, CG31042, Spase12, spase12" IPR009542:Microsomal signal peptidase 12kDa subunit CG11500 11-Aug-17 DroID_v2017_08 Drer\spcs1 Scer\SPC1 Cele\C34B2.10 Xtro\spcs1 Mmus\Spcs1 Hsap\SPCS1 "lethal - all die during embryonic stage,recessive,visible,somatic clone,planar polarity defective,melanotic mass phenotype" "eye,somatic clone,leg,antenna,melanotic mass,ommatidium,interommatidial bristle" FBgn0004561 Su(var)321 Suppressor of variegation 321 http://flybase.org/reports/FBgn0004561 - gene - - - "Su(var)231, Su(var)321" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0065339 l(2)SH1838 lethal (2) SH1838 http://flybase.org/reports/FBgn0065339 gene - - - "l(2)SH1838, l(2)SH2 1838" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013352 Antp::Ubx Antp::Ubx http://flybase.org/reports/FBgn0013352 - engineered_fusion_gene - - - Antp::Ubx - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "Keilin's organ,mesothoracic tracheal pit,metathoracic tracheal pit,metathoracic ventral denticle belt,denticle belt,embryonic/first instar larval cuticle" FBgn0028310 l(1)G0369 lethal (1) G0369 http://flybase.org/reports/FBgn0028310 gene - - - l(1)G0369 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0053876 His2B:CG33876 His2B:CG33876 http://flybase.org/reports/FBgn0053876 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33876, His2B:CG33876" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33876 11-Aug-17 DroID_v2017_08 "Drer\zgc:173587, Drer\zgc:92591, Drer\zgc:114046, Drer\LOC100334869, Drer\si:ch1073-153i20.3, Drer\si:dkey-108k21.27, Drer\si:dkey-23a13.1, Drer\hist2h2l, Drer\si:dkey-108k21.11, Drer\hist1h2ba, Drer\si:ch211-113a14.28, Drer\si:ch1073-159d7.13, Drer\LOC100329560, Drer\si:dkey-23a13.16, Drer\si:ch73-36p18.3, Drer\si:dkey-23a13.5, Drer\si:ch211-113a14.29, Drer\zgc:173585, Drer\ano9a, Drer\si:ch73-368j24.8, Drer\si:dkey-261m9.6, Drer\si:ch211-113a14.11, Drer\LOC100334559, Drer\zgc:194989, Drer\si:ch1073-159d7.5, Drer\si:dkey-261m9.19, Drer\LOC100329290" "Scer\HTB2, Scer\HTB1" "Cele\his-62, Cele\his-48, Cele\his-11, Cele\his-15, Cele\his-58, Cele\his-44, Cele\his-8, Cele\his-52, Cele\his-34, Cele\his-66, Cele\his-20, Cele\his-39, Cele\his-22, Cele\his-29, Cele\his-4, Cele\his-54, Cele\his-41" "Xtro\hist2h2be, Xtro\LOC101731067, Xtro\LOC100485294, Xtro\LOC101731959, Xtro\LOC100492632, Xtro\LOC101730940, Xtro\LOC101734862, Xtro\LOC100495578, Xtro\hist1h2bj, Xtro\LOC100498553, Xtro\LOC101734494, Xtro\LOC100498647, Xtro\LOC100487485, Xtro\LOC100497915, Xtro\LOC101733489, Xtro\hist1h2bk, Xtro\LOC100495415, Xtro\LOC100495041, Xtro\LOC101735164, Xtro\LOC100486870, Xtro\LOC101733171, Xtro\LOC101731852, Xtro\LOC100497082, Xtro\LOC101733828, Xtro\hist1h2bm, Xtro\LOC100485134, Xtro\LOC100496436, Xtro\LOC101735218, Xtro\LOC100486150, Xtro\LOC100496445, Xtro\LOC100496181, Xtro\LOC100498329, Xtro\LOC100495396, Xtro\LOC100498072" "Mmus\Hist1h2br, Mmus\Hist1h2bh, Mmus\Hist1h2bc, Mmus\Hist1h2bm, Mmus\Hist2h2be, Mmus\Hist3h2ba, Mmus\Hist1h2bf, Mmus\Hist1h2bp, Mmus\Hist1h2bn, Mmus\Hist1h2bk, Mmus\Hist1h2bq, Mmus\Hist1h2bl, Mmus\Hist1h2bg, Mmus\Hist2h2bb, Mmus\Hist1h2bj, Mmus\H2bfm, Mmus\Hist1h2be, Mmus\Hist1h2ba, Mmus\Hist1h2bb, Mmus\1700024P04Rik" "Hsap\HIST3H2BB, Hsap\HIST2H2BF, Hsap\H2BFM, Hsap\H2BFWT, Hsap\HIST1H2BC, Hsap\HIST2H2BE, Hsap\HIST1H2BJ, Hsap\HIST1H2BL, Hsap\HIST1H2BO, Hsap\HIST1H2BG, Hsap\HIST1H2BI, Hsap\HIST1H2BA, Hsap\HIST1H2BK, Hsap\HIST1H2BD, Hsap\HIST1H2BH, Hsap\HIST1H2BE, Hsap\HIST1H2BN, Hsap\HIST1H2BB, Hsap\HIST1H2BM, Hsap\HIST1H2BF" FBgn0000636 Fas3 Fasciclin 3 http://flybase.org/reports/FBgn0000636 - protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from biological aspect of ancestor with PANTHER:PTN000589024 receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000589024 cell adhesion molecule binding ; GO:0050839 | inferred from biological aspect of ancestor with PANTHER:PTN000589024 receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000589024 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from biological aspect of ancestor with PANTHER:PTN000589024 homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from direct assay synaptic target recognition ; GO:0008039 | inferred from mutant phenotype synaptic target attraction ; GO:0016200 | traceable author statement axonal fasciculation ; GO:0007413 | traceable author statement axon guidance ; GO:0007411 | inferred from expression pattern olfactory learning ; GO:0008355 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement neuromuscular junction ; GO:0031594 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay septate junction ; GO:0005918 | traceable author statement cell-cell adherens junction ; GO:0005913 | inferred from biological aspect of ancestor with PANTHER:PTN000589024 nuclear membrane ; GO:0031965 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay lateral plasma membrane ; GO:0016328 | traceable author statement cytosol ; GO:0005829 | inferred from direct assay smooth septate junction ; GO:0005920 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000589024 basolateral plasma membrane ; GO:0016323 | non-traceable author statement fusome ; GO:0045169 | spectrosome ; GO:0045170 | "FasIII, FASIII, fasIII, Fas III, CG5803, Fas-3, FAS III, FAS3, fas III, Fas-III, fas-III, fascIII, Fas3, FasIIIface, FascIII, Fas, fas3" "IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold" CG5803 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-214p13.3, Drer\si:ch211-149e23.4, Drer\si:dkey-15j16.3, Drer\zgc:113337, Drer\cadm3, Drer\si:ch211-119e14.9, Drer\si:ch211-141e20.2, Drer\crtam, Drer\cadm2b, Drer\cadm1a, Drer\cadm4, Drer\cadm2a, Drer\pvrl3b, Drer\si:dkey-31e10.1, Drer\pvrl4, Drer\si:ch211-222f23.6, Drer\si:dkey-281i8.1, Drer\si:dkey-31e10.5, Drer\zgc:174863, Drer\mcamb, Drer\sc:d189, Drer\si:ch73-22o12.1, Drer\pvrl1a, Drer\pvrl2l, Drer\zgc:172122, Drer\cd226, Drer\pvrl1b, Drer\pvrl3a, Drer\cadm1b, Drer\gypc" - Cele\igcm-1 - "Mmus\Cadm2, Mmus\Tigit, Mmus\Nectin2, Mmus\Gm609, Mmus\Nectin1, Mmus\Pvr, Mmus\Nectin3, Mmus\Crtam, Mmus\Cadm3, Mmus\Cadm4, Mmus\Cd200, Mmus\Smagp, Mmus\Cadm1, Mmus\Gypc, Mmus\Cd226, Mmus\Nectin4" "Hsap\CRTAM, Hsap\KIRREL3, Hsap\CD200, Hsap\NECTIN1, Hsap\PVR, Hsap\NPHS1, Hsap\SMAGP, Hsap\NECTIN2, Hsap\CD226, Hsap\GYPC, Hsap\CADM1, Hsap\CADM4, Hsap\TIGIT, Hsap\NECTIN4, Hsap\NECTIN3, Hsap\CADM3, Hsap\CADM2, Hsap\NCR3" " embryonic stage | stage 12 , adult stage , adult stage && oogenesis stage , embryonic stage | stage 15-17 , embryonic stage " " visceral mesoderm

, germarium && follicle cell

, polar follicle cell

, RP3 neuron

, embryonic/larval visceral muscle

" "lethal,memory defective,neuroanatomy defective,viable,recessive,behavior defective,visible,partially lethal - majority die,some die during pupal stage" "aCC neuron,abdominal segmental nerve,RP3 motor neuron,abdominal 2 ventral longitudinal muscle 3,abdominal 3 ventral longitudinal muscle 3,abdominal 4 ventral longitudinal muscle 3,abdominal 5 ventral longitudinal muscle 3,abdominal 6 ventral longitudinal muscle 3,abdominal 7 ventral longitudinal muscle 3,abdominal 2 ventral longitudinal muscle 4,abdominal 3 ventral longitudinal muscle 4,abdominal 4 ventral longitudinal muscle 4,abdominal 5 ventral longitudinal muscle 4,abdominal 6 ventral longitudinal muscle 4,abdominal 7 ventral longitudinal muscle 4,RP3 neuron & growth cone,abdominal ventral muscle,dorsal appendage,maternal effect,trichogen cell,mesothoracic tergum" FBgn0024188 san separation anxiety http://flybase.org/reports/FBgn0024188 FBgn0033626 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from sequence model N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN002451866 N-acetyltransferase activity ; GO:0008080 | inferred from sequence or structural similarity with UniProtKB:Q9QY36 peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from direct assay mitotic sister chromatid cohesion ; GO:0007064 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype N-terminal protein amino acid acetylation ; GO:0006474 | inferred from biological aspect of ancestor with PANTHER:PTN000558165 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype N-terminal protein amino acid acetylation ; GO:0006474 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay protein acetyltransferase complex ; GO:0031248 | inferred from physical interaction with NAT1 inferred from physical interaction with vnc cohesin complex ; GO:0008278 | inferred from direct assay NatA complex ; GO:0031415 | inferred from direct assay NatA complex ; GO:0031415 | inferred from biological aspect of ancestor with PANTHER:PTN000558165 "DmAAF34715, CG12352, span, san, atado, NAA50, Naa50, dNaa50, San" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG12352 11-Aug-17 DroID_v2017_08 "Drer\rnf113a, Drer\naa50" "Scer\CWC24, Scer\NAT5" "Cele\F54E7.9, Cele\rnf-113, Cele\F40F4.7" "Xtro\naa50, Xtro\rnf113a" "Mmus\Naa50, Mmus\Rnf113a1" "Hsap\NAA50, Hsap\RNF113A, Hsap\RNF113B" "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,mitotic cell cycle defective,immune response defective,viable,visible" "embryonic/larval brain,imaginal disc,nucleus | embryonic stage 4 | germline clone,SO0000340chromosome | embryonic stage 4 | germline clone,chromosome & larval neuroblast,somatic clone,follicle cell,mitotic cell cycle,mitosis & nuclear chromosome,chaeta,trichogen cell,tormogen cell" DRSC07695 K 1.001119951 0.111055785 0.322090571 -0.275285957 0.565148296 1.761717976 FBgn0060514 l(3)S103914b lethal (3) S103914b http://flybase.org/reports/FBgn0060514 gene - - - "1039/14, l(3)S103914b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005734 l(1)TK219 lethal (1) TK219 http://flybase.org/reports/FBgn0005734 - gene - - - "l219, l(1)TK219" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0013531 MED20 Mediator complex subunit 20 http://flybase.org/reports/FBgn0013531 "FBgn0031983, FBgn0042121" protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from electronic annotation with InterPro:IPR013921 transcription coactivator activity ; GO:0003713 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from direct assay "Med20, Trfp, TrfP, Srb2/TRFP, dTrfp, p29, dTrap26, Tmr, l(2)28DE, CG18267, CG18780, MED20, med20" "IPR013921:Mediator complex, subunit Med20" CG18780 11-Aug-17 DroID_v2017_08 Drer\med20 Scer\SRB2 Cele\mdt-20 Xtro\med20 "Mmus\Usp49, Mmus\Med20" Hsap\MED20 spermatogenesis && adult stage " testis

, spermatocyte

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069134 mcl(3)Z6259 mcl(3)Z6259 http://flybase.org/reports/FBgn0069134 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z6259 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0002930 nec necrotic http://flybase.org/reports/FBgn0002930 "FBgn0024292, FBgn0028676, FBgn0033148, FBgn0063807" protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from direct assay serine-type endopeptidase inhibitor activity ; GO:0004867 | non-traceable author statement negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | traceable author statement regulation of proteolysis ; GO:0030162 | inferred from mutant phenotype antifungal humoral response ; GO:0019732 | traceable author statement inferred from genetic interaction with spz regulation of proteolysis ; GO:0030162 | inferred from direct assay immune response ; GO:0006955 | inferred from expression pattern response to fungus ; GO:0009620 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Spn43Ac, CG1857, SER3, Ser3, anon-WO0118057.3, nec, Nec, NEC" "IPR000215:Serpin family, IPR023796:Serpin domain, IPR023795:Serpin, conserved site" CG1857 11-Aug-17 DroID_v2017_08 "Drer\serpina7, Drer\serpinb1l3, Drer\serpinf2a, Drer\serpinb1l2, Drer\serpinc1, Drer\serpinf2b, Drer\serpina1l, Drer\serpine2, Drer\serpinb1, Drer\zgc:173729, Drer\agt, Drer\si:ch1073-416d2.3, Drer\serpinf1, Drer\zgc:174259, Drer\serpind1, Drer\serpine1, Drer\serpini1, Drer\serpine3, Drer\si:ch211-186e20.7, Drer\serping1" - "Cele\srp-3, Cele\C28G1.2, Cele\srp-8, Cele\srp-1, Cele\srp-2, Cele\srp-7, Cele\srp-6" "Xtro\serpina3k, Xtro\serpini1, Xtro\serpinb4, Xtro\serpine1, Xtro\serpina10, Xtro\serpind1, Xtro\serpina3, Xtro\serpini2, Xtro\serpinb11, Xtro\serpinb5, Xtro\serpina3m, Xtro\serpinb1, Xtro\serpina1, Xtro\serpinc1, Xtro\serpine2, Xtro\serpinb6" "Mmus\Serpinb3c, Mmus\Serpinb7, Mmus\Serpina9, Mmus\Serpina6, Mmus\Serpine1, Mmus\Serpine2, Mmus\Serpina1c, Mmus\Serpinb9, Mmus\Serpinb5, Mmus\Serpina3j, Mmus\Serpinb6d, Mmus\Serpinb1a, Mmus\Serpini1, Mmus\Serpina3i, Mmus\Serpina1e, Mmus\Serpinb6a, Mmus\Serpina3a, Mmus\Serpina1a, Mmus\Serpina1d, Mmus\Serpina12, Mmus\Serpinb3a, Mmus\Serpinb3d, Mmus\Serpinb8, Mmus\Serpinb1c, Mmus\Serpina11, Mmus\Serpinc1, Mmus\Serpinb11, Mmus\Serpinb9c, Mmus\Serpina16, Mmus\Serpina10, Mmus\Serpina3k, Mmus\Serpinb1b, Mmus\Serpind1, Mmus\Serpinf2, Mmus\Serpina3n, Mmus\Serpinb12, Mmus\Serpina1f, Mmus\Serpinb9f, Mmus\Serpinb9e, Mmus\Serpinb9b, Mmus\Serpinb6b, Mmus\Serpinb6e, Mmus\Agt, Mmus\Serpina7, Mmus\Serpini2, Mmus\Serpina5, Mmus\Serpinb2, Mmus\Serpina3f, Mmus\Serpina3g, Mmus\Serpina3c, Mmus\Serpinb6c, Mmus\Serpinb13, Mmus\Serpine3, Mmus\Serpinf1" "Hsap\SERPINB5, Hsap\SERPINB11, Hsap\SERPINA4, Hsap\SERPINB8, Hsap\SERPINE3, Hsap\SERPIND1, Hsap\SERPINA2, Hsap\SERPINA10, Hsap\SERPINB6, Hsap\SERPINF2, Hsap\SERPINB4, Hsap\SERPINB9, Hsap\SERPINI2, Hsap\SERPINA9, Hsap\SERPINC1, Hsap\SERPINB2, Hsap\SERPINE2, Hsap\SERPINE1, Hsap\SERPINA11, Hsap\SERPINB13, Hsap\SERPINA12, Hsap\SERPINB7, Hsap\SERPINF1, Hsap\SERPINA6, Hsap\SERPINA1, Hsap\AGT, Hsap\SERPINA3, Hsap\SERPINA7, Hsap\SERPINB10, Hsap\SERPINI1, Hsap\SERPINB12, Hsap\SERPINA5, Hsap\SERPINB1" "wild-type,short lived,heat sensitive,partially lethal - majority live,lethal,recessive,visible,melanotic necrosis,female sterile,some die during immature adult stage,non-enhancer of variegation,non-suppressor of variegation" "joint,adult integumentary system,adult epidermis,adult abdomen,adult cuticle" FBgn0028516 ZnT35C Zinc transporter 35C http://flybase.org/reports/FBgn0028516 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 metal ion transmembrane transporter activity ; GO:0046873 | inferred from sequence or structural similarity zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016324 cation transport ; GO:0006812 | inferred from electronic annotation with InterPro:IPR002524 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002524 regulation of sequestering of zinc ion ; GO:0061088 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 response to zinc ion ; GO:0010043 | inferred from mutant phenotype detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002524 cytoplasmic vesicle ; GO:0031410 | inferred from biological aspect of ancestor with PANTHER:PTN000169638 apical plasma membrane ; GO:0016324 | inferred from direct assay "BG:DS07295.1, CG3994, ZnT35C, dZnT35C, cg3994" "IPR002524:Cation efflux protein, IPR027470:Cation efflux protein, cytoplasmic domain" CG3994 11-Aug-17 DroID_v2017_08 "Drer\slc30a4, Drer\slc30a2, Drer\slc30a1a, Drer\slc30a1b, Drer\slc30a8" "Scer\ZRC1, Scer\COT1" "Cele\cdf-2, Cele\cdf-1, Cele\ttm-1" "Xtro\slc30a8, Xtro\slc30a3, Xtro\slc30a4, Xtro\slc30a2" "Mmus\Slc30a2, Mmus\Slc30a3, Mmus\Slc30a4, Mmus\Slc30a10, Mmus\Slc30a1, Mmus\Slc30a8" "Hsap\SLC30A10, Hsap\SLC30A4, Hsap\SLC30A1, Hsap\SLC30A2, Hsap\SLC30A3, Hsap\SLC30A8" "chemical resistant,viable,chemical sensitive,melanotic mass phenotype" melanotic mass FBgn0003545 sub subito http://flybase.org/reports/FBgn0003545 "FBgn0013911, FBgn0034273" protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity microtubule motor activity ; GO:0003777 | inferred from mutant phenotype ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" meiotic spindle midzone assembly ; GO:0051257 | inferred from direct assay mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype metaphase/anaphase transition of mitotic cell cycle ; GO:0007091 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype inferred from genetic interaction with ncd female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype inferred from genetic interaction with ncd inferred from genetic interaction with nod microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 embryonic cleavage ; GO:0040016 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule associated complex ; GO:0005875 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity spindle microtubule ; GO:0005876 | inferred from direct assay spindle pole ; GO:0000922 | inferred from mutant phenotype "mei-1794, CG12298, Dub, sub, Mklp2, SUB, subito, DmKlp54E, Sub, KIF 20A, DmSub, KIF20A/B" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12298 11-Aug-17 DroID_v2017_08 "Drer\kif23, Drer\kif20a, Drer\kif20bb, Drer\zgc:56231, Drer\si:dkey-96l17.6, Drer\kif20ba" "Scer\KIP2, Scer\SMY1" "Cele\klp-7, Cele\zen-4" "Xtro\kif20a, Xtro\kif23" "Mmus\Kif20a, Mmus\Kif23, Mmus\Kif20b" "Hsap\KIF20A, Hsap\KIF23, Hsap\KIF20B" "female sterile,recessive,lethal,maternal effect,mitotic cell cycle defective,meiotic cell cycle defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,female fertile,reduced,visible,dominant,heat sensitive,male sterile,lethal - all die before end of pupal stage,some die during pupal stage,viable" "spindle,spindle & oocyte,brain,spindle microtubule | larval stage,spindle pole & oocyte,karyosome,spindlePclXM82),chromosome, centromeric regionPC4),eye,wing,wing margin,heat sensitive,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7,macrochaeta,spindle midzone & oocyte,chaeta,supernumerary,trichogen cell,spindle microtubule & oocytenos.UTR.THsimVP16,spindle microtubule & stage S14 oocytenos.UTR.THsimVP16,spindle | ectopicnos.UTR.THsimVP16,oocyte" FBgn0053898 His2B:CG33898 His2B:CG33898 http://flybase.org/reports/FBgn0053898 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33898, His2B:CG33898" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33898 11-Aug-17 DroID_v2017_08 "Drer\LOC100329290, Drer\LOC100329560, Drer\zgc:194989, Drer\hist1h2ba, Drer\si:dkey-108k21.11, Drer\si:ch73-36p18.3, Drer\si:dkey-108k21.27, Drer\si:dkey-23a13.16, Drer\LOC100334869, Drer\si:dkey-23a13.5, Drer\LOC100334559, Drer\zgc:173585, Drer\si:ch211-113a14.11, Drer\zgc:92591, Drer\zgc:114046, Drer\si:dkey-261m9.6, Drer\si:dkey-261m9.19, Drer\hist2h2l, Drer\si:ch1073-153i20.3, Drer\si:ch1073-159d7.13, Drer\si:ch211-113a14.29, Drer\si:ch73-368j24.8, Drer\si:ch1073-159d7.5, Drer\ano9a, Drer\si:dkey-23a13.1, Drer\zgc:173587, Drer\si:ch211-113a14.28" "Scer\HTB1, Scer\HTB2" "Cele\his-15, Cele\his-22, Cele\his-44, Cele\his-48, Cele\his-39, Cele\his-4, Cele\his-62, Cele\his-34, Cele\his-11, Cele\his-29, Cele\his-54, Cele\his-41, Cele\his-66, Cele\his-58, Cele\his-8, Cele\his-20, Cele\his-52" "Xtro\hist2h2be, Xtro\LOC100497915, Xtro\LOC101731067, Xtro\LOC100498329, Xtro\LOC100498647, Xtro\LOC100498553, Xtro\LOC101731852, Xtro\LOC101731959, Xtro\LOC100496181, Xtro\LOC100486150, Xtro\LOC100495578, Xtro\hist1h2bk, Xtro\LOC100485134, Xtro\LOC101733828, Xtro\LOC101733171, Xtro\LOC101733489, Xtro\LOC100492632, Xtro\LOC101735218, Xtro\LOC101734862, Xtro\LOC100485294, Xtro\LOC101730940, Xtro\LOC101734494, Xtro\hist1h2bm, Xtro\hist1h2bj, Xtro\LOC100496436, Xtro\LOC100495415, Xtro\LOC101735164, Xtro\LOC100495041, Xtro\LOC100487485, Xtro\LOC100496445, Xtro\LOC100495396, Xtro\LOC100486870, Xtro\LOC100498072, Xtro\LOC100497082" "Mmus\Hist1h2bc, Mmus\Hist1h2be, Mmus\Hist3h2ba, Mmus\Hist1h2ba, Mmus\Hist1h2bq, Mmus\Hist1h2bh, Mmus\Hist1h2bg, Mmus\Hist1h2bp, Mmus\Hist1h2bf, Mmus\Hist1h2br, Mmus\Hist1h2bb, Mmus\Hist1h2bl, Mmus\Hist2h2bb, Mmus\Hist1h2bk, Mmus\Hist1h2bn, Mmus\Hist1h2bm, Mmus\Hist1h2bj, Mmus\1700024P04Rik, Mmus\Hist2h2be, Mmus\H2bfm" "Hsap\HIST2H2BF, Hsap\HIST1H2BB, Hsap\HIST1H2BC, Hsap\HIST1H2BL, Hsap\HIST1H2BE, Hsap\HIST1H2BO, Hsap\HIST1H2BG, Hsap\HIST1H2BK, Hsap\HIST1H2BH, Hsap\HIST3H2BB, Hsap\HIST1H2BN, Hsap\H2BFWT, Hsap\HIST1H2BA, Hsap\H2BFM, Hsap\HIST1H2BI, Hsap\HIST1H2BM, Hsap\HIST1H2BD, Hsap\HIST1H2BJ, Hsap\HIST2H2BE, Hsap\HIST1H2BF" FBgn0053908 His2B:CG33908 His2B:CG33908 http://flybase.org/reports/FBgn0053908 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33908, His2B:CG33908" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33908 11-Aug-17 DroID_v2017_08 "Drer\hist2h2l, Drer\si:ch1073-159d7.5, Drer\ano9a, Drer\si:dkey-261m9.19, Drer\si:dkey-23a13.16, Drer\zgc:92591, Drer\zgc:173585, Drer\zgc:114046, Drer\si:ch1073-159d7.13, Drer\si:dkey-108k21.27, Drer\zgc:173587, Drer\si:dkey-23a13.1, Drer\LOC100329290, Drer\hist1h2ba, Drer\si:dkey-261m9.6, Drer\si:dkey-108k21.11, Drer\LOC100329560, Drer\LOC100334559, Drer\si:ch73-36p18.3, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.5, Drer\si:ch1073-153i20.3, Drer\zgc:194989, Drer\si:ch211-113a14.29, Drer\si:ch73-368j24.8, Drer\LOC100334869, Drer\si:ch211-113a14.28" "Scer\HTB2, Scer\HTB1" "Cele\his-41, Cele\his-29, Cele\his-54, Cele\his-34, Cele\his-66, Cele\his-22, Cele\his-44, Cele\his-39, Cele\his-4, Cele\his-11, Cele\his-58, Cele\his-20, Cele\his-15, Cele\his-62, Cele\his-8, Cele\his-52, Cele\his-48" "Xtro\LOC101733828, Xtro\LOC101733171, Xtro\LOC100495578, Xtro\LOC100492632, Xtro\LOC100487485, Xtro\hist1h2bm, Xtro\LOC101734862, Xtro\LOC100496436, Xtro\LOC101735164, Xtro\LOC100496445, Xtro\LOC100498329, Xtro\LOC100498647, Xtro\LOC101731067, Xtro\LOC101735218, Xtro\LOC100495396, Xtro\hist2h2be, Xtro\LOC101731959, Xtro\LOC100495041, Xtro\LOC101734494, Xtro\LOC100496181, Xtro\hist1h2bj, Xtro\LOC101731852, Xtro\LOC100497082, Xtro\LOC101730940, Xtro\LOC100485134, Xtro\LOC100486150, Xtro\LOC100495415, Xtro\LOC100498553, Xtro\LOC100498072, Xtro\LOC100486870, Xtro\LOC100485294, Xtro\LOC101733489, Xtro\LOC100497915, Xtro\hist1h2bk" "Mmus\Hist1h2bj, Mmus\Hist1h2bp, Mmus\Hist1h2be, Mmus\Hist3h2ba, Mmus\Hist1h2bk, Mmus\Hist1h2ba, Mmus\Hist1h2bn, Mmus\Hist1h2bc, Mmus\1700024P04Rik, Mmus\H2bfm, Mmus\Hist1h2bg, Mmus\Hist2h2be, Mmus\Hist1h2br, Mmus\Hist1h2bl, Mmus\Hist1h2bb, Mmus\Hist1h2bf, Mmus\Hist1h2bh, Mmus\Hist1h2bq, Mmus\Hist2h2bb, Mmus\Hist1h2bm" "Hsap\HIST2H2BF, Hsap\HIST1H2BG, Hsap\HIST1H2BO, Hsap\HIST3H2BB, Hsap\HIST1H2BK, Hsap\HIST1H2BL, Hsap\HIST2H2BE, Hsap\HIST1H2BA, Hsap\HIST1H2BI, Hsap\HIST1H2BC, Hsap\HIST1H2BN, Hsap\H2BFWT, Hsap\H2BFM, Hsap\HIST1H2BE, Hsap\HIST1H2BD, Hsap\HIST1H2BM, Hsap\HIST1H2BB, Hsap\HIST1H2BF, Hsap\HIST1H2BH, Hsap\HIST1H2BJ" FBgn0053899 His4:CG33899 His4:CG33899 http://flybase.org/reports/FBgn0053899 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33899, His4:CG33899" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33899 11-Aug-17 DroID_v2017_08 "Drer\zgc:194989, Drer\LOC562770, Drer\LOC100150038, Drer\LOC100331412, Drer\hist1h4l, Drer\si:ch73-36p18.4, Drer\si:ch73-36p18.3, Drer\si:dkey-108k21.12, Drer\si:dkey-261m9.17, Drer\si:dkey-261m9.18, Drer\LOC794549, Drer\si:dkey-108k21.28, Drer\si:ch211-113a14.17, Drer\si:dkey-23a13.7, Drer\zgc:153409, Drer\LOC570405, Drer\si:ch211-113a14.26, Drer\si:ch73-368j24.1, Drer\zgc:163040, Drer\si:ch211-113a14.6, Drer\si:dkey-108k21.19, Drer\zgc:154164, Drer\si:ch73-368j24.14, Drer\LOC100329358" "Scer\HHF2, Scer\HHF1" "Cele\his-64, Cele\his-10, Cele\his-31, Cele\his-56, Cele\his-28, Cele\his-67, Cele\his-5, Cele\his-37, Cele\his-18, Cele\his-26, Cele\his-60, Cele\his-46, Cele\his-1, Cele\his-38, Cele\his-50, Cele\his-14" "Xtro\hist1h4c, Xtro\hist1h4k, Xtro\LOC100493041" "Mmus\Hist1h4m, Mmus\Hist1h4c, Mmus\Hist1h4a, Mmus\Hist1h4b, Mmus\Hist2h4, Mmus\Hist1h4d, Mmus\Hist4h4, Mmus\Hist1h4i, Mmus\Hist1h4k, Mmus\Hist1h4f, Mmus\Hist1h4n, Mmus\Hist1h4h, Mmus\Hist1h4j" "Hsap\HIST2H4B, Hsap\HIST1H4L, Hsap\HIST1H4B, Hsap\HIST1H4E, Hsap\HIST4H4, Hsap\HIST1H4D, Hsap\HIST1H4G, Hsap\HIST1H4C, Hsap\HIST1H4I, Hsap\HIST1H4A, Hsap\HIST1H4F, Hsap\HIST1H4K, Hsap\HIST1H4J, Hsap\HIST2H4A, Hsap\HIST1H4H" FBgn0053887 His4:CG33887 His4:CG33887 http://flybase.org/reports/FBgn0053887 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33887, His4:CG33887" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33887 11-Aug-17 DroID_v2017_08 "Drer\hist1h4l, Drer\si:ch73-36p18.4, Drer\si:dkey-23a13.7, Drer\si:dkey-108k21.28, Drer\zgc:154164, Drer\LOC570405, Drer\LOC562770, Drer\si:dkey-108k21.12, Drer\zgc:194989, Drer\si:ch73-36p18.3, Drer\zgc:163040, Drer\si:ch211-113a14.26, Drer\si:ch211-113a14.17, Drer\zgc:153409, Drer\si:ch211-113a14.6, Drer\LOC100331412, Drer\si:dkey-261m9.18, Drer\LOC100150038, Drer\si:ch73-368j24.14, Drer\si:dkey-261m9.17, Drer\LOC100329358, Drer\LOC794549, Drer\si:ch73-368j24.1, Drer\si:dkey-108k21.19" "Scer\HHF2, Scer\HHF1" "Cele\his-37, Cele\his-56, Cele\his-60, Cele\his-18, Cele\his-38, Cele\his-64, Cele\his-1, Cele\his-10, Cele\his-5, Cele\his-31, Cele\his-46, Cele\his-28, Cele\his-26, Cele\his-14, Cele\his-50, Cele\his-67" "Xtro\LOC100493041, Xtro\hist1h4c, Xtro\hist1h4k" "Mmus\Hist1h4i, Mmus\Hist1h4n, Mmus\Hist1h4h, Mmus\Hist1h4f, Mmus\Hist1h4m, Mmus\Hist2h4, Mmus\Hist1h4j, Mmus\Hist1h4c, Mmus\Hist1h4d, Mmus\Hist4h4, Mmus\Hist1h4k, Mmus\Hist1h4a, Mmus\Hist1h4b" "Hsap\HIST1H4L, Hsap\HIST2H4A, Hsap\HIST4H4, Hsap\HIST1H4E, Hsap\HIST1H4F, Hsap\HIST1H4J, Hsap\HIST1H4I, Hsap\HIST1H4K, Hsap\HIST2H4B, Hsap\HIST1H4B, Hsap\HIST1H4A, Hsap\HIST1H4C, Hsap\HIST1H4D, Hsap\HIST1H4H, Hsap\HIST1H4G" FBgn0026620 tacc transforming acidic coiled-coil protein http://flybase.org/reports/FBgn0026620 - protein_coding_gene microtubule binding ; GO:0008017 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with msps female meiotic division ; GO:0007143 | traceable author statement protein localization ; GO:0008104 | inferred from mutant phenotype negative regulation of microtubule depolymerization ; GO:0007026 | traceable author statement pronuclear fusion ; GO:0007344 | traceable author statement pole cell formation ; GO:0007279 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype nuclear migration ; GO:0007097 | inferred from mutant phenotype protein localization ; GO:0008104 | traceable author statement microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from biological aspect of ancestor with PANTHER:PTN001016925 mitotic spindle organization ; GO:0007052 | traceable author statement pronuclear migration ; GO:0035046 | inferred from mutant phenotype negative regulation of microtubule depolymerization ; GO:0007026 | non-traceable author statement microtubule cytoskeleton organization ; GO:0000226 | inferred from biological aspect of ancestor with PANTHER:PTN001016925 centrosome ; GO:0005813 | colocalizes_with inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay microtubule cytoskeleton ; GO:0015630 | inferred from biological aspect of ancestor with PANTHER:PTN001016925 centrosome ; GO:0005813 | traceable author statement spindle pole ; GO:0000922 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001016925 spindle microtubule ; GO:0005876 | traceable author statement pericentriolar material ; GO:0000242 | non-traceable author statement astral microtubule ; GO:0000235 | traceable author statement "D-TACC, d-tacc, dtacc, D-tacc, DTACC, dTACC, TACC, acc, CG9765, tacc, TACCdm" IPR007707:Transforming acidic coiled-coil-containing protein CG9765 11-Aug-17 DroID_v2017_08 "Drer\tacc3, Drer\tacc1, Drer\tacc2" - Cele\tac-1 "Xtro\tacc2, Xtro\tacc3" "Mmus\Tacc3, Mmus\Tacc1, Mmus\Tacc2" "Hsap\TACC3, Hsap\TACC1, Hsap\TACC2" embryonic stage organism

"mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,female sterile" "astral microtubule,centrosome | ectopic,spindle & oocyte,embryonic/larval salivary gland,spindle,aster,mitotic cell cycle,nucleus | embryonic stage,microtubule,pericentriolar material,centrosome,pronucleus,oocyte & spindle110),pole cell" DRSC12388 K -0.164039046 0.566755502 -0.196411409 0.731475413 1.941975919 -0.013831568 FBgn0062581 Mod(var)242 Mod(var)242 http://flybase.org/reports/FBgn0062581 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "242, Mod(var)242" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,lethal,recessive" FBgn0017571 Mow Modifier of white http://flybase.org/reports/FBgn0017571 - gene - - - "mow, Mow" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,suppressor of variegation,lethal" pigment cell FBgn0002696 mdg midgoid http://flybase.org/reports/FBgn0002696 - gene - - - mdg - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,male sterile,viable,male,reduced,body color defective" FBgn0035520 CG11586 - http://flybase.org/reports/FBgn0035520 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN001128910 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN001128911 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000002256" U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN001128911 CG11586 "IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013087:Zinc finger C2H2-type, IPR022755:Zinc finger, double-stranded RNA binding" CG11586 11-Aug-17 DroID_v2017_08 Drer\zmat2 Scer\SNU23 Cele\snu-23 Xtro\zmat2 Mmus\Zmat2 Hsap\ZMAT2 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0052423 shep alan shepard http://flybase.org/reports/FBgn0052423 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002343 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype response to gravity ; GO:0009629 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern female courtship behavior ; GO:0008050 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG32423, anon-EST:Posey83, CG10668, cg10668, CG10649, CG10647, BcDNA:RH63980, BcDNA:LD40028, anon-WO0172774.41, anon-WO0118547.198, alan, shep, alan-shepard, Shep" "IPR000504:RNA recognition motif domain, IPR002343:Paraneoplastic encephalomyelitis antigen" CG32423 11-Aug-17 DroID_v2017_08 "Drer\rbms2a, Drer\rbms1a, Drer\rbms3, Drer\rbms2b" Scer\PAB1 Cele\sup-26 "Xtro\rbms1, Xtro\rbms2" "Mmus\Rbms2, Mmus\Rbms3, Mmus\Rbms1" "Hsap\RBMS2, Hsap\RBMS1, Hsap\RBMS3" "viable,gravitaxis defective,fertile,lethal" DRSC09765 E 0.185809986 0.84776836 -0.533988261 1.687702344 0.264859607 -0.044039804 FBgn0003677 Tcr Third chromosome alpha methyl dopa-resistant http://flybase.org/reports/FBgn0003677 - gene - - - "l(3)Tcr, Tcr" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemical resistant,dominant,lethal,recessive,uncoordinated" FBgn0042134 Capr Caprin http://flybase.org/reports/FBgn0042134 protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay "cellularization ; GO:0007349 | inferred from mutant phenotype regulation of mitotic cell cycle, embryonic ; GO:0009794 | inferred from genetic interaction with Fmr1 negative regulation of imaginal disc growth ; GO:0045571 | inferred from genetic interaction with rin inferred from genetic interaction with lig inferred from genetic interaction with Fmr1" intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "NEST:bs19b07, anon-WO0118547.253, dFAP, Capr, CG18811" IPR011989:Armadillo-like helical CG18811 11-Aug-17 DroID_v2017_08 "Drer\c1ql1, Drer\caprin1a, Drer\cbln1, Drer\c1ql2, Drer\si:dkeyp-74b6.2, Drer\cbln4, Drer\cbln2b, Drer\cbln2a, Drer\c1ql3a, Drer\cbln12, Drer\caprin2, Drer\c1ql4b, Drer\caprin1b, Drer\si:dkey-5n18.1, Drer\c1ql4a, Drer\c1ql3b" - - "Xtro\cbln2, Xtro\c1ql1, Xtro\c1ql4, Xtro\caprin1, Xtro\cbln4, Xtro\c1ql3, Xtro\caprin2, Xtro\cbln1" "Mmus\C1ql1, Mmus\Caprin1, Mmus\C1ql4, Mmus\Cbln3, Mmus\C1qtnf3, Mmus\C1ql2, Mmus\Cbln2, Mmus\Cbln4, Mmus\Cbln1, Mmus\Caprin2, Mmus\C1ql3" "Hsap\C1QL1, Hsap\C1QL4, Hsap\AMACR, Hsap\CBLN3, Hsap\CAPRIN1, Hsap\C1QL3, Hsap\CBLN4, Hsap\CBLN2, Hsap\CBLN1, Hsap\CAPRIN2, Hsap\C1QL2" "size defective,somatic clone,somatic clone - Minute background,nutrition conditional,viable,mitotic cell cycle defective,maternal effect,fertile,visible,partially lethal - majority die,some die during pupal stage" "ommatidium,somatic clone,somatic clone - Minute background,trichogen cell" FBgn0052594 be ben http://flybase.org/reports/FBgn0052594 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E, CG5530, anon-EST:CL1a5, CG15026, BEST:LD10566, ben, be, CG32594" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR012334:Pectin lyase fold, IPR011050:Pectin lyase fold/virulence factor" CG32594 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage >5 , embryonic stage | stage 5 , embryonic stage | stage 11 , embryonic stage | stage 8 , embryonic stage " " mesoderm

, mesoderm anlage

, mesectoderm

, head

, vitellophage

, yolk

" "neuroanatomy defective,viable,lethal,recessive,memory defective,neurophysiology defective" synapse FBgn0260814 EY04392 - http://flybase.org/reports/FBgn0260814 gene - - - EY04392 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,visible" "embryonic/larval central nervous system,neurite | pharate adult stage,adult brain,adult central nervous system,wing" FBgn0016716 Reg-20 Rhythmically expressed gene 20 http://flybase.org/reports/FBgn0016716 - gene - - - "Dreg-20, Reg-20" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | late , adult stage " adult head

FBgn0015291 Sebp1 Secretion enhancer-binding protein 1 http://flybase.org/reports/FBgn0015291 - gene RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from genetic interaction with Pig1, Sgs4" nucleus ; GO:0005634 | inferred from direct assay Sebp1 - - 11-Aug-17 DroID_v2017_08 - - - - - - larval stage | third instar embryonic/larval salivary gland

FBgn0000212 brm brahma http://flybase.org/reports/FBgn0000212 FBgn0036554 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR014978 histone binding ; GO:0042393 | inferred from electronic annotation with InterPro:IPR029295 DNA-dependent ATPase activity ; GO:0008094 | inferred from sequence or structural similarity with UniProtKB:P51532 protein binding ; GO:0005515 | inferred from physical interaction with CycE inferred from physical interaction with Snr1 protein binding ; GO:0005515 | inferred from physical interaction with mor ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with SGD:S000005816 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V464" "ATP-dependent chromatin remodeling ; GO:0043044 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay ATP-dependent chromatin remodeling ; GO:0043044 | inferred from sequence or structural similarity with SGD:S000005816 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from genetic interaction with numb inferred from genetic interaction with brat regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from genetic interaction with e(y)3 neuron development ; GO:0048666 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with SGD:S000005816 histone H3-K27 acetylation ; GO:0043974 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of innate immune response ; GO:0045088 | inferred from mutant phenotype inferred from genetic interaction with Rel positive regulation of stem cell proliferation ; GO:2000648 | inferred from mutant phenotype hemocyte proliferation ; GO:0035172 | traceable author statement hippo signaling ; GO:0035329 | inferred from genetic interaction with sd inferred from genetic interaction with yki inferred from genetic interaction with hpo inferred from physical interaction with sd inferred from physical interaction with yki ventral cord development ; GO:0007419 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from genetic interaction with CycE axonogenesis ; GO:0007409 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype" SWI/SNF complex ; GO:0016514 | inferred from electronic annotation with InterPro:IPR030088 brahma complex ; GO:0035060 | traceable author statement brahma complex ; GO:0035060 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay PBAF complex ; GO:0070604 | inferred from direct assay "BRM, CG5942, Brm, dBRM, CG18438, E(E2F)3A, l(3)72Aa, brm, dSNF2, Brm @ Kto, BRD, dSMARCA4, Brahma, brahma" "IPR018359:Bromodomain, conserved site, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014012:Helicase/SANT-associated domain, IPR000330:SNF2-related, N-terminal domain, IPR001487:Bromodomain, IPR001650:Helicase, C-terminal, IPR006576:BRK domain, IPR014978:Glutamine-Leucine-Glutamine, QLQ, IPR030088:SWI/SNF complex subunit SMARCA2, IPR029295:Snf2, ATP coupling domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5942 11-Aug-17 DroID_v2017_08 "Drer\LOC100001344, Drer\smarca2, Drer\LOC100535713, Drer\smarca4a, Drer\hells" "Scer\SNF2, Scer\STH1" "Cele\swsn-4, Cele\C52B9.8" "Xtro\smarca2, Xtro\smarca4, Xtro\hells" "Mmus\Smarca4, Mmus\Smarca2, Mmus\Hells" "Hsap\SMARCA4, Hsap\SMARCA2, Hsap\HELLS" ", adult stage | female , embryonic stage--pupal stage " unfertilized egg

" larval stage , larval stage | third instar " " larval salivary gland

, ventral thoracic disc

, dorsal mesothoracic disc

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective,visible,viable,fertile,lethal,enhancer of variegation,dominant,male,homeotic,somatic clone,cell shape defective,wild-type,increased cell size,lethal - all die before end of P-stage,partially,some die during pharate adult stage,heat sensitive,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage" "dendritic arborizing neuron,axon,dendrite,wing,eye,ommatidium,macrochaeta,abdominal segment 6,mechanosensory chaeta & adult head | somatic clone,mechanosensory chaeta & adult thorax | somatic clone,mechanosensory chaeta & adult abdomen | somatic clone,embryonic/larval hemocyte,humeral bristle,adult antennal lobe projection neuron DL1 adPN,somatic clone,adult abdominal segment 6,adult abdominal segment 5,ectopic,photoreceptor cell,eye disc,wing sensillum,wing margin bristle,wing vein,posterior,proximal,wing vein L5,distal,posterior crossvein,sensillum campaniformium,macrochaeta & wing69B,prothoracic leg,sex comb,mechanosensory chaeta,sensillum campaniformium & wing69B,thecogen cell,tormogen cell,eo neuron,wing disc | third instar larval stage,capitellum & macrochaeta,haltere,capitellum,wing margin,wing hair,embryonic/larval neuroblast,ganglion mother cell,type II neuroblast,supernumerary" DRSC11330 IEK -0.969023502 -2.462179569 -2.086064123 0.36355782 0.607310471 2.423519817 FBgn0040252 Ugt86Dh Ugt86Dh http://flybase.org/reports/FBgn0040252 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG4772, AC 006491H, Ugt86Dh" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG4772 11-Aug-17 DroID_v2017_08 "Drer\ugt5d1, Drer\ugt2b6, Drer\ugt5b6, Drer\ugt5g2, Drer\ugt5c2, Drer\ugt1b3, Drer\ugt2b5, Drer\ugt1b2, Drer\ugt5a2, Drer\ugt5b2, Drer\ugt2b1, Drer\ugt5f1, Drer\ugt5b1, Drer\ugt5a5, Drer\ugt2b3, Drer\ugt2a6, Drer\ugt1b5, Drer\ugt1ab, Drer\ugt5a1, Drer\ugt5a4, Drer\ugt5e1, Drer\ugt2a2, Drer\ugt5c1, Drer\zgc:172315, Drer\ugt5b4, Drer\ugt5g1, Drer\ugt8, Drer\ugt1b4, Drer\ugt5c3, Drer\ugt2a5, Drer\ugt1b7, Drer\ugt5b3" Scer\ATG26 "Cele\ugt-45, Cele\ugt-52, Cele\ugt-10, Cele\ugt-27, Cele\ugt-65, Cele\ugt-43, Cele\ugt-56, Cele\ugt-35, Cele\ugt-9, Cele\ugt-12, Cele\ugt-40, Cele\ugt-58, Cele\ugt-32, Cele\ugt-19, Cele\ugt-15, Cele\ugt-44, Cele\ugt-3, Cele\ugt-28, Cele\ugt-54, Cele\ugt-41, Cele\ugt-6, Cele\ugt-11, Cele\ugt-21, Cele\ugt-53, Cele\ugt-61, Cele\K04A8.10, Cele\ugt-8, Cele\C03A7.12, Cele\ugt-7, Cele\C55H1.1, Cele\ugt-17, Cele\ugt-42, Cele\ugt-25, Cele\ugt-50, Cele\ugt-14, Cele\ugt-39, Cele\ugt-48, Cele\F10D2.8, Cele\ugt-18, Cele\ugt-38, Cele\ugt-5, Cele\ugt-20, Cele\H23N18.4, Cele\ugt-37, Cele\ugt-1, Cele\ugt-4, Cele\ugt-13, Cele\ugt-29, Cele\ugt-23, Cele\ugt-26, Cele\ugt-49, Cele\ugt-46, Cele\ugt-59, Cele\ugt-51, Cele\ugt-31, Cele\ugt-60, Cele\ugt-30, Cele\ugt-55, Cele\ugt-47, Cele\ugt-36, Cele\ugt-33, Cele\C23G10.6, Cele\ugt-24, Cele\ugt-34, Cele\Y43D4A.2, Cele\C03A7.13, Cele\ugt-22, Cele\ugt-16, Cele\F54C1.1, Cele\ugt-2, Cele\ugt-62" "Xtro\ugt2a1, Xtro\ugt2b4, Xtro\ugt3a2, Xtro\ugt8, Xtro\ugt1a6" "Mmus\Ugt1a10, Mmus\Ugt2b5, Mmus\Ugt2a2, Mmus\Ugt2b37, Mmus\Ugt2b1, Mmus\Ugt1a2, Mmus\Ugt1a6b, Mmus\Ugt1a1, Mmus\Ugt2b38, Mmus\Ugt1a9, Mmus\Ugt1a5, Mmus\Ugt1a7c, Mmus\Ugt3a2, Mmus\Ugt2b35, Mmus\Ugt2b34, Mmus\Ugt8a, Mmus\Ugt3a1, Mmus\Ugt2b36, Mmus\Ugt2a1, Mmus\Ugt2a3" "Hsap\UGT2B15, Hsap\UGT1A9, Hsap\UGT2B28, Hsap\UGT1A8, Hsap\UGT1A1, Hsap\UGT2B11, Hsap\UGT2A3, Hsap\UGT8, Hsap\UGT2A2, Hsap\UGT1A4, Hsap\UGT2B17, Hsap\UGT1A6, Hsap\UGT1A3, Hsap\UGT2B10, Hsap\UGT2B7, Hsap\UGT1A7, Hsap\UGT3A2, Hsap\UGT3A1, Hsap\UGT1A10, Hsap\UGT2B4, Hsap\UGT1A5" viable FBgn0029768 SPR Sex peptide receptor http://flybase.org/reports/FBgn0029768 protein_coding_gene "G-protein coupled peptide receptor activity ; GO:0008528 | inferred from physical interaction with SP, Mip, Dup99B G-protein coupled peptide receptor activity ; GO:0008528 | inferred from physical interaction with SP" "regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 plasma membrane ; GO:0005886 | inferred from direct assay" "DrmSPR, CG12731, CG16752, SPR, spr" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR019427:7TM GPCR, serpentine receptor class w (Srw), IPR017452:GPCR, rhodopsin-like, 7TM" CG16752 11-Aug-17 DroID_v2017_08 "Drer\adra1ba, Drer\gper1, Drer\gpr142, Drer\exorh, Drer\valopa, Drer\gpr35.1" - "Cele\sprr-3, Cele\C25F9.13, Cele\C24B5.1, Cele\sprr-2, Cele\M01G12.6, Cele\W10C4.1, Cele\F16C3.1, Cele\sprr-1, Cele\T10E10.3" - "Mmus\Gpr142, Mmus\Cysltr2, Mmus\Cysltr1, Mmus\Gpr139" "Hsap\P2RY8, Hsap\GPR139, Hsap\P2RY10, Hsap\GPR142" "partially lethal - majority die,some die during pupal stage,courtship behavior defective,female,behavior defective,viable,mating behavior defective" DRSC18114 K 0.874683259 0.44488452 -0.077779679 0.333115431 -0.594402872 -1.591679647 FBgn0002989 okr okra http://flybase.org/reports/FBgn0002989 FBgn0017554 protein_coding_gene "hydrolase activity, acting on acid anhydrides ; GO:0016817 | inferred from electronic annotation with InterPro:IPR013967 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330" dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from mutant phenotype oocyte fate determination ; GO:0030716 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | traceable author statement DNA synthesis involved in double-strand break repair via homologous recombination ; GO:0043150 | inferred from mutant phenotype double-strand break repair via synthesis-dependent strand annealing ; GO:0045003 | inferred from mutant phenotype DNA recombination ; GO:0006310 | inferred from sequence or structural similarity double-strand break repair ; GO:0006302 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from genetic interaction with p53 intracellular mRNA localization ; GO:0008298 | traceable author statement regulation of translation ; GO:0006417 | traceable author statement oogenesis ; GO:0048477 | traceable author statement meiotic DNA repair synthesis ; GO:0000711 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | traceable author statement response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype DNA repair ; GO:0006281 | non-traceable author statement double-strand break repair ; GO:0006302 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "rad54, Rad54, RAD54, DmRad54, DmRAD54, DhR54, CG3736, okr, okra, Ras54, RAD54L, Dmrad54, Okr, OKR" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013967:Rad54, N-terminal" CG3736 11-Aug-17 DroID_v2017_08 "Drer\rad54l, Drer\rad54b" "Scer\RAD54, Scer\RDH54" "Cele\rad-54, Cele\Y116A8C.13" "Xtro\rad54b, Xtro\rad54l" "Mmus\Rad54b, Mmus\Rad54l" "Hsap\RAD54L, Hsap\RAD54B" " oogenesis stage , oogenesis stage && adult stage | female , embryonic stage--pupal stage " ovary

"wild-type,viable,female fertile,reduced,female sterile,chemical sensitive,recessive,radiation sensitive,male fertile,maternal effect,sterile,fertile,meiotic cell cycle defective,rescuable maternal effect,DNA repair defective" "eye disc,conditional,metaphase & condensed nuclear chromosome | conditional qualifier,presumptive oocyte,karyosome,dorsal appendage,chorion | maternal effect,chorion,nucleus,egg,oocyte,micropyle,follicle cell" FBgn0027088 GlyRS Glycyl-tRNA synthetase http://flybase.org/reports/FBgn0027088 FBgn0036477 protein_coding_gene "glycine-tRNA ligase activity ; GO:0004820 | inferred from electronic annotation with InterPro:IPR002315 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000738, InterPro:IPR002314, InterPro:IPR002315 glycine-tRNA ligase activity ; GO:0004820 | traceable author statement" glycyl-tRNA aminoacylation ; GO:0006426 | inferred from electronic annotation with InterPro:IPR002315 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype glycyl-tRNA aminoacylation ; GO:0006426 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement "CG6778, GlyRS, GRS, gars, team, Aat-gly, GARS, Gars, dGars, Aats-gly" "IPR000738:WHEP-TRS domain, IPR002314:Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR002315:Glycyl-tRNA synthetase, IPR004154:Anticodon-binding, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR009068:S15/NS1, RNA-binding, IPR027031:Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2, IPR033731:Glycyl-tRNA synthetase-like core domain" CG6778 11-Aug-17 DroID_v2017_08 "Drer\gars, Drer\polg2" "Scer\GRS2, Scer\GRS1" Cele\gars-1 "Xtro\polg2, Xtro\gars" "Mmus\Gars, Mmus\Polg2" "Hsap\GARS, Hsap\POLG2" embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "neuroanatomy defective,somatic clone,lethal,partially lethal - majority live,viable,partially lethal - majority die,majority die during P-stage,gravitaxis defective,progressive,neurophysiology defective,visible,lethal - all die before end of first instar larval stage,lethal - all die before end of pupal stage" "adult antennal lobe projection neuron DL1 adPN,somatic clone,neuroblast ALad1,gamma Kenyon cell,giant fiber neuron,eye" FBgn0034646 Rae1 Rae1 http://flybase.org/reports/FBgn0034646 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with hiw inferred from physical interaction with Nup98-96 inferred from physical interaction with Fsn regulation of autophagy ; GO:0010506 | inferred from mutant phenotype regulation of G1/S transition of mitotic cell cycle ; GO:2000045 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay male meiosis I ; GO:0007141 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | NOT inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype Nebenkern ; GO:0016006 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay sperm flagellum ; GO:0036126 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from physical interaction with Nup98-96 "CG9862, dmrae1, Rae1, rae1" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG9862 11-Aug-17 DroID_v2017_08 Drer\rae1 Scer\GLE2 Cele\rae-1 Xtro\rae1 Mmus\Rae1 Hsap\RAE1 "viable,male sterile,recessive,meiotic cell cycle defective,mitotic cell cycle defective,body size defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,visible" "Nebenkern,primary spermatocyte,onion stage spermatid,elongation stage spermatid,spermatozoon,meiotic spindle,centriole,centrosome,embryonic/larval neuromuscular junction,embryonic/larval somatic muscle,synapse,NMJ bouton,synapseXE-2900),trichogen cell,mesothoracic tergum" FBgn0020057 E(w[a])709 E(w[a])709 http://flybase.org/reports/FBgn0020057 - gene - - - "E709, E(w[a])709" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0069175 mcl(2)Z4635 mcl(2)Z4635 http://flybase.org/reports/FBgn0069175 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z4635 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile FBgn0028183 l(3)S024135 lethal (3) S024135 http://flybase.org/reports/FBgn0028183 gene - - - "0241/35, l(3)S024135" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053803 His3:CG33803 His3:CG33803 http://flybase.org/reports/FBgn0053803 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33803, His3:CG33803" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33803 11-Aug-17 DroID_v2017_08 "Drer\h3f3b.1, Drer\zgc:173552, Drer\LOC108190747, Drer\si:ch1073-429i10.3, Drer\cenpa, Drer\zgc:113983, Drer\h3f3a, Drer\zgc:113984, Drer\h3f3c, Drer\h3f3d, Drer\hist2h3ca1, Drer\si:ch73-36p18.2, Drer\LOC108190746, Drer\hist2h3c" "Scer\HHT2, Scer\CSE4, Scer\HHT1" "Cele\his-69, Cele\his-9, Cele\his-49, Cele\his-55, Cele\his-63, Cele\his-25, Cele\his-42, Cele\his-6, Cele\his-45, Cele\his-72, Cele\his-27, Cele\his-2, Cele\his-32, Cele\his-74, Cele\his-71, Cele\his-17, Cele\his-13, Cele\his-59" "Xtro\hist2h3d, Xtro\cenpa, Xtro\h3f3b" "Mmus\Hist1h3c, Mmus\Hist1h3e, Mmus\Hist2h3b, Mmus\H3f3a, Mmus\Hist1h3h, Mmus\Hist1h3g, Mmus\Hist2h3c1, Mmus\Hist1h3d, Mmus\Hist1h3b, Mmus\H3f3b, Mmus\Cenpa, Mmus\Hist1h3f, Mmus\Hist2h3c2, Mmus\Hist1h3i, Mmus\Hist1h3a" "Hsap\H3F3C, Hsap\HIST2H3C, Hsap\HIST1H3J, Hsap\HIST1H3I, Hsap\HIST2H3A, Hsap\HIST3H3, Hsap\HIST1H3F, Hsap\HIST1H3C, Hsap\HIST2H3D, Hsap\HIST1H3G, Hsap\HIST1H3A, Hsap\HIST1H3H, Hsap\CENPA, Hsap\H3F3A, Hsap\HIST1H3E, Hsap\HIST1H3D, Hsap\H3F3B, Hsap\HIST1H3B" FBgn0053839 His3:CG33839 His3:CG33839 http://flybase.org/reports/FBgn0053839 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33839, His3:CG33839" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33839 11-Aug-17 DroID_v2017_08 "Drer\LOC108190747, Drer\zgc:113984, Drer\cenpa, Drer\h3f3d, Drer\si:ch1073-429i10.3, Drer\h3f3a, Drer\h3f3c, Drer\si:ch73-36p18.2, Drer\zgc:173552, Drer\zgc:113983, Drer\LOC108190746, Drer\h3f3b.1, Drer\hist2h3ca1, Drer\hist2h3c, Drer\si:dkey-261m9.8" "Scer\CSE4, Scer\HHT2, Scer\HHT1" "Cele\his-6, Cele\his-59, Cele\his-72, Cele\his-25, Cele\his-32, Cele\his-17, Cele\his-27, Cele\his-2, Cele\his-69, Cele\his-13, Cele\his-45, Cele\his-49, Cele\his-55, Cele\his-9, Cele\his-42, Cele\his-74, Cele\his-63, Cele\his-71" "Xtro\h3f3b, Xtro\hist2h3d, Xtro\cenpa, Xtro\LOC101731074" "Mmus\Hist1h3a, Mmus\Hist1h3h, Mmus\Hist2h3b, Mmus\H3f3a, Mmus\Hist1h3g, Mmus\Hist2h3c1, Mmus\Hist1h3b, Mmus\Hist2h3c2, Mmus\Hist1h3c, Mmus\Hist1h3d, Mmus\Cenpa, Mmus\H3f3b, Mmus\Gm12657, Mmus\Hist1h3f, Mmus\Hist1h3i, Mmus\Hist1h3e" "Hsap\HIST1H3C, Hsap\H3F3B, Hsap\HIST1H3E, Hsap\HIST1H3A, Hsap\HIST1H3I, Hsap\HIST2H3A, Hsap\HIST2H3C, Hsap\H3F3C, Hsap\H3F3A, Hsap\HIST1H3B, Hsap\HIST2H3D, Hsap\HIST1H3J, Hsap\HIST3H3, Hsap\HIST1H3H, Hsap\HIST1H3D, Hsap\HIST1H3G, Hsap\HIST1H3F, Hsap\CENPA" FBgn0053863 His3:CG33863 His3:CG33863 http://flybase.org/reports/FBgn0053863 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33863, His3:CG33863" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33863 11-Aug-17 DroID_v2017_08 "Drer\LOC108190746, Drer\si:ch1073-429i10.3, Drer\zgc:113984, Drer\h3f3a, Drer\h3f3d, Drer\hist2h3c, Drer\si:dkey-261m9.8, Drer\si:ch73-36p18.2, Drer\h3f3c, Drer\hist2h3ca1, Drer\cenpa, Drer\LOC108190747, Drer\zgc:173552, Drer\h3f3b.1, Drer\zgc:113983" "Scer\HHT1, Scer\CSE4, Scer\HHT2" "Cele\his-49, Cele\his-27, Cele\his-63, Cele\his-55, Cele\his-25, Cele\his-13, Cele\his-59, Cele\his-74, Cele\his-32, Cele\his-6, Cele\his-69, Cele\his-9, Cele\his-72, Cele\his-42, Cele\his-45, Cele\his-71, Cele\his-17, Cele\his-2" "Xtro\LOC100497406, Xtro\h3f3b, Xtro\hist2h3d, Xtro\cenpa" "Mmus\H3f3b, Mmus\Hist1h3c, Mmus\Hist1h3f, Mmus\Hist1h3i, Mmus\Hist1h3g, Mmus\Hist2h3c1, Mmus\Hist1h3h, Mmus\Hist1h3d, Mmus\Hist1h3a, Mmus\Hist2h3c2, Mmus\Cenpa, Mmus\H3f3a, Mmus\Hist2h3b, Mmus\Hist1h3b, Mmus\Hist1h3e" "Hsap\HIST1H3A, Hsap\HIST1H3E, Hsap\H3F3B, Hsap\HIST1H3B, Hsap\H3F3A, Hsap\HIST1H3C, Hsap\H3F3C, Hsap\HIST1H3F, Hsap\HIST2H3A, Hsap\HIST1H3H, Hsap\HIST1H3J, Hsap\HIST2H3C, Hsap\HIST1H3G, Hsap\HIST1H3I, Hsap\CENPA, Hsap\HIST1H3D, Hsap\HIST3H3, Hsap\HIST2H3D" FBgn0022023 eIF3h eukaryotic translation initiation factor 3 subunit h http://flybase.org/reports/FBgn0022023 FBgn0027910 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR027524 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from electronic annotation with InterPro:IPR027524 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from sequence or structural similarity "eIf3-p44, eIF3-S3, CG9124, l(2)k09003, eIF-3, BcDNA:GM14618, eIF3h, eIF-3p40, Q9U9Q4" "IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR027524:Eukaryotic translation initiation factor 3 subunit H" CG9124 11-Aug-17 DroID_v2017_08 "Drer\eif3hb, Drer\eif3ha" - Cele\eif-3.H Xtro\eif3h Mmus\Eif3h Hsap\EIF3H "lethal,recessive,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "ganglion mother cell,embryonic/larval neuroblast,wing,wing margin bristle" FBgn0003701 thr three rows http://flybase.org/reports/FBgn0003701 FBgn0015333 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24454 inferred from physical interaction with UniProtKB:Q9VRN6 peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | traceable author statement mitotic sister chromatid separation ; GO:0051306 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype digestive tract mesoderm development ; GO:0007502 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "thr, THR, CG5785, anch, ana, Thr, frag1" - CG5785 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | cellular blastoderm , embryonic stage , larval stage | third instar , embryonic stage | syncytial blastoderm , embryonic stage | stage 13 , embryonic stage | extended germ band , adult stage " "

ubiquitous , ventral nerve cord

, embryonic central nervous system

, embryonic brain | restricted

, embryonic peripheral nervous system

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,mitotic cell cycle defective,heat sensitive,cytokinesis defective,visible,maternal effect,cold sensitive,partially lethal - majority die,some die during pupal stage" "mitosis | embryonic stage,presumptive embryonic/larval peripheral nervous system,gonad,gonadal sheath proper primordium,visceral mesoderm,Malpighian tubule,embryonic/larval foregut,embryonic/larval hindgut,midgut constriction,embryonic head,embryonic epidermis,embryonic/larval trachea,cycle 15 embryo & anaphase & condensed nuclear chromosome,cleavage nucleus,metaphase plate,embryonic/larval esophagus,denticle belt,mitotic cell cycle | embryonic stage,eye,ommatidium,syncytial blastoderm embryo,maternal effect,stage 5 embryo,centrosome | maternal effect,aster | maternal effect,mesothoracic tergum" DRSC07706 E -1.276969475 -0.650594425 0.304746002 -2.971042431 0.164730376 -0.963548781 FBgn0001169 H Hairless http://flybase.org/reports/FBgn0001169 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with asf1 transcription corepressor activity ; GO:0003714 | inferred from direct assay somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | traceable author statement regulation of cell death ; GO:0010941 | inferred from mutant phenotype intestinal stem cell homeostasis ; GO:0036335 | inferred from genetic interaction with mir-305 sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | non-traceable author statement imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype nucleus ; GO:0005634 | traceable author statement "H, CG5460" - CG5460 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , pupal stage | >16 hr , adult stage && oogenesis stage , embryonic stage | early , pupal stage | early , larval stage | third instar stage 2 " " mesoderm

, embryonic central nervous system

, tormogen cell

, labral segment

, nurse cell

, central nervous system

, posterior embryonic/larval midgut

, head

, epithelial cell &&of dorsal mesothoracic disc

, cephalic furrow

, imaginal disc

, anterior embryonic/larval midgut

, procephalic segment

" "visible,dominant,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell death,decreased cell number,somatic clone,heat sensitive,size defective,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,viable,partially lethal - majority die,some die during pupal stage" "sensory mother cell,eo neuron,thecogen cell,ectopic,tormogen cell,photoreceptor cell,somatic clone,eye,cone cell | pupal stage,eye disc | pupal stage,wing disc,wing blade,wing margin,wing vein,wing margin bristle,eye disc,ommatidium,wing,campaniform sensillum of anterior crossvein,precursor,sensillum campaniformium of dorsal radius,dorsal row & sensory mother cellap-md544,adult cuticle,macrochaeta,heat sensitive,intestinal stem cell,supernumerary,cone cell,microchaeta,wing disc | third instar larval stage,wing vein L5,anterior orbital bristle,ocellar bristle,mesothoracic tergum & macrochaeta | somatic clone,cell autonomous,medial triple row,socket,sense organ,trichogen cell,chaeta,postvertical bristle,occipital bristle,wing vein L2,wing vein L4,neuron,macrochaeta & head,macrochaeta & scutum,scutellar bristle,eo sensory structure,microchaeta & tormogen cell | conditional ts,wing & macrochaeta,wing vein L3,anterior dorsocentral bristle,head bristle,microchaeta & trichogen cell,upper humeral bristle,posterior orbital bristle,posterior vertical bristle,presutural bristle,posterior postalar bristle,posterior crossvein,dorsal hair,microchaeta & scutum,mesothoracic tergum & macrochaeta,macrochaeta & adult head,adult head & microchaeta,sternopleural bristle,interfollicle cell,adult head & macrochaeta,adult thorax & macrochaeta,leg sensillum,adult abdominal sensillum,adult abdominal sensillum & sternite,dorsal mesothoracic disc & cell,head & macrochaeta,scutum & macrochaeta,external sensory organ precursor cell,wing & microchaeta | ectopicen-e16E,embryonic hindgut,haltere,adult thorax,adult thorax & macrochaetaT113,muscle founder cell,embryonic/larval somatic muscle,peripheral nervous system,tracheal branch primordium,mesothoracic tergum" FBgn0020054 E(w[a])761 E(w[a])761 http://flybase.org/reports/FBgn0020054 - gene - - - "E761, E(w[a])761" - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0020412 JIL-1 JIL-1 kinase http://flybase.org/reports/FBgn0020412 "FBgn0003592, FBgn0062055" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017892 histone kinase activity (H3-S10 specific) ; GO:0035175 | inferred from mutant phenotype protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay histone kinase activity (H3-S10 specific) ; GO:0035175 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KQZ4 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with protein_id:AAA49959.1 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" protein autophosphorylation ; GO:0046777 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement histone phosphorylation ; GO:0016572 | traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype histone phosphorylation ; GO:0016572 | inferred from direct assay histone phosphorylation ; GO:0016572 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 protein phosphorylation ; GO:0006468 | inferred from direct assay chromatin organization ; GO:0006325 | traceable author statement female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype negative regulation of chromatin silencing ; GO:0031936 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype "cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 nucleus ; GO:0005634 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | inferred from physical interaction with UniProtKB:P50534 inferred from physical interaction with UniProtKB:P50535" "Jil1, JIL1, JIL-1, MSK, JIL, CG6297, Jil-1, 2Ab17, Su(var)3-1, Su(var)3-103, Su-var(3)103, Su-var(3)1, anon-WO0118547.379, IL-1, MSK1, mAb2A" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal" CG6297 11-Aug-17 DroID_v2017_08 "Drer\rps6ka2, Drer\akt2, Drer\rps6ka3b, Drer\stk32a, Drer\sgk3, Drer\LOC100331306, Drer\rps6ka4, Drer\rps6ka5, Drer\akt3a, Drer\rps6kb1a, Drer\sgk1, Drer\rps6ka1, Drer\akt3b, Drer\si:ch211-195b13.1, Drer\sgk2a, Drer\sgk2b, Drer\rps6ka3a, Drer\rps6kb1b, Drer\rps6kal" "Scer\YPK1, Scer\YPK2, Scer\CTK1, Scer\SCH9, Scer\YPK3" "Cele\rskd-1, Cele\rskn-2" "Xtro\sgk1, Xtro\rps6ka5, Xtro\rps6ka2, Xtro\rps6kb1, Xtro\sgk2, Xtro\rps6ka4, Xtro\akt2, Xtro\stk32a, Xtro\rps6ka3, Xtro\akt1, Xtro\rps6ka6, Xtro\rps6ka1" "Mmus\Akt2, Mmus\Sgk1, Mmus\Sgk3, Mmus\Stk32c, Mmus\Rps6kb2, Mmus\Akt1, Mmus\Rps6ka1, Mmus\Rps6ka2, Mmus\Rps6ka6, Mmus\Akt3, Mmus\Rps6ka3, Mmus\Stk32a, Mmus\Rps6kb1, Mmus\Rps6ka4, Mmus\Stk32b, Mmus\Rps6ka5, Mmus\Sgk2" "Hsap\RPS6KA4, Hsap\SGK3, Hsap\AKT3, Hsap\RPS6KA2, Hsap\RPS6KA5, Hsap\RPS6KA6, Hsap\RPS6KB1, Hsap\RPS6KA3, Hsap\RPS6KB2, Hsap\STK32C, Hsap\AKT2, Hsap\STK32A, Hsap\SGK1, Hsap\STK32B, Hsap\AKT1, Hsap\SGK2, Hsap\RPS6KA1" "viable,modifier of variegation,enhancer of variegation,suppressor of variegation,fertile,lethal - all die before end of embryonic stage,maternal effect,partially,some die during embryonic stage,visible,homeotic,lethal,recessive,meiotic cell cycle defective,dominant,partially lethal - majority die,mitotic cell cycle defective,female sterile,non-suppressor of variegation,wild-type" "polytene chromosome | larval stagehs.PB,intersegmental nerve,abdominal sternite 6,male,abdominal sternite 5,ectopic,ovary,spindle[-],chromatin[-],nucleus[-],polytene chromosome[-],polytene chromosome,polytene chromosome | male,polytene chromosome band | male,euchromatin,polytene chromosome interband,embryonic/larval neuroblast,spindle | third instar larval stage,polytene chromosome | larval stage,egg,ovariole,egg chamber,nurse cell,oocyte nucleus" DRSC11200 I -0.716145845 3.977689898 -0.259961019 1.137845901 0.206385358 -0.21727481 FBgn0038118 timeout timeout http://flybase.org/reports/FBgn0038118 protein_coding_gene - entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype - "tim2, dtim2, TIM2, CG8148, CG14382, CG14381, CG7855, timeout" "IPR006906:Timeless protein, IPR007725:Timeless C-terminal, IPR011990:Tetratricopeptide-like helical domain" CG7855 11-Aug-17 DroID_v2017_08 Drer\timeless Scer\TOF1 Cele\tim-1 Xtro\timeless Mmus\Timeless Hsap\TIMELESS "lethal - all die before end of P-stage,recessive,some die during P-stage,viable,fertile,locomotor rhythm defective,dominant,lethal - all die before end of pupal stage,some die during pupal stage,visible" "SO0000340chromosome | larval stageExel6167),SO0000340chromosome | larval stage,head,eye,trichogen cell" FBgn0001809 l(1)ml lethal (1) melanomalike http://flybase.org/reports/FBgn0001809 - gene - - - l(1)ml - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "melanotic mass,egg chamber,maternal effect" FBgn0005348 sf-3 safranin on 3 http://flybase.org/reports/FBgn0005348 - gene - - - sf-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,eye color defective" pigment cell FBgn0004531 l(4)102CDb lethal (4) 102CDb http://flybase.org/reports/FBgn0004531 - gene - - - "l(4)AM-3, l(4)23, l(4)102CDb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005636 nvy nervy http://flybase.org/reports/FBgn0005636 - protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR003894 zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN000822368" "muscle organ development ; GO:0007517 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from biological aspect of ancestor with PANTHER:PTN000822368 chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000822368 nucleus ; GO:0005634 | inferred from direct assay "CG3385, nvy, Nvy, nervy" "IPR002893:Zinc finger, MYND-type, IPR003894:TAFH/NHR1, IPR013289:CBFA2T family, IPR013293:Nervy, IPR014896:NHR2-like" CG3385 11-Aug-17 DroID_v2017_08 "Drer\cbfa2t3, Drer\runx1t1, Drer\zgc:153702" - - "Xtro\cbfa2t3, Xtro\runx1t1, Xtro\cbfa2t2" "Mmus\Cbfa2t3, Mmus\Runx1t1, Mmus\Cbfa2t2" "Hsap\CBFA2T3, Hsap\CBFA2T2, Hsap\RUNX1T1" embryonic stage | stage >=9 " central nervous system | restricted

, embryonic peripheral nervous system | restricted

, neuroblast

" "neuroanatomy defective,lethal,viable" "sensory mother cell,somatic clone,abdominal intersegmental nerve,presumptive embryonic/larval central nervous system,ventral nerve cord,lateral longitudinal fascicle,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,abdominal segmental nerve,mechanosensory sensory organ & thoraxpnr-MD237,medial longitudinal fascicle,adult thorax & mechanosensory sensory organ-537.4,adult thorax | dorsal & mechanosensory sensory organpnr-MD237,cell non-autonomous,adult thorax & mechanosensory sensory organ | somatic clone‘±Tub84B.PZ,mechanosensory neuron,thecogen cell,mechanosensory sensory organ,cuticle" DRSC04705 E 1.024897471 0.402026107 2.644289032 0.137988583 -0.121210071 1.06207011 FBgn0027169 l(2)ESH1 lethal (2) ESH1 http://flybase.org/reports/FBgn0027169 - gene - - - l(2)ESH1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0025172 l(2)38Dd lethal (2) 38Dd http://flybase.org/reports/FBgn0025172 - gene - - - l(2)38Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0082634 S(CycE[JP])2.13 S(CycE[JP])2.13 http://flybase.org/reports/FBgn0082634 gene - - - "2.13, S(CycE[JP])2.13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260496 l(3)7 - http://flybase.org/reports/FBgn0260496 gene - - - l(3)7 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective dendritic arborizing neuron FBgn0003002 opa odd paired http://flybase.org/reports/FBgn0003002 - protein_coding_gene "transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0001205 | inferred from mutant phenotype transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with ci inferred from sequence or structural similarity with HGNC:4319 RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay" decapentaplegic signaling pathway ; GO:0008101 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from expression pattern inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG1133, opa, Opa" "IPR013087:Zinc finger C2H2-type, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1133 11-Aug-17 DroID_v2017_08 "Drer\zic6, Drer\zic2b, Drer\zic1, Drer\zic2a, Drer\zic5, Drer\zic4, Drer\zic3" Scer\ZAP1 Cele\ref-2 "Xtro\zic3, Xtro\zic5, Xtro\zic4, Xtro\zic2" "Mmus\Zic1, Mmus\Zic5, Mmus\Zic2, Mmus\Zic4, Mmus\Zic3" "Hsap\ZIC5, Hsap\ZNF671, Hsap\ZNF619, Hsap\ZIC4, Hsap\ZIC1, Hsap\ZIC3, Hsap\ZIC2, Hsap\ZNF616" " embryonic stage | stage 6 , embryonic stage | stage 5 , embryonic stage | stage 7 , embryonic stage | stage 11-12 , embryonic stage | stage 5,6 , embryonic stage--pupal stage , embryonic stage | stage 13-17 " " mesoderm

, organism | 10-80% egg length

, organism | striped

, visceral mesoderm

,

20-80% egg length , organism | 80% egg length

, visceral mesoderm &&of parasegment 9--12

, parasegment 5 &&of visceral mesoderm

, ectoderm

" " embryonic stage | stage 5-7 , embryonic stage | stage 7 " "

20-80% egg length , organism | striped

" "visible,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,heat sensitive,pair rule phenotype" "heart primordium,adult head,somatic clone,ventral,eye,rostral membrane,vibrissae,maxillary palpus,antenna,heat sensitive,gena,denticle belt,embryonic segment,midgut constriction,embryonic/first instar larval cuticle,embryonic maxillary segment,gonadal sheath proper primordium,fat body/gonad primordium,embryonic/larval cuticle,eye disc,antennal disc,arista,supernumerary,adult antennal segment" DRSC26411 K -0.960754575 -0.001004104 -0.145380117 0.055374035 -0.453412534 1.948458852 FBgn0035147 Gale UDP-galactose 4'-epimerase http://flybase.org/reports/FBgn0035147 protein_coding_gene UDP-N-acetylglucosamine 4-epimerase activity ; GO:0003974 | inferred from mutant phenotype UDP-glucose 4-epimerase activity ; GO:0003978 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype galactose metabolic process ; GO:0006012 | inferred from mutant phenotype - "Gale, CG12030, dGALE, GALE" "IPR005886:UDP-glucose 4-epimerase, IPR008089:Nucleotide sugar epimerase, IPR016040:NAD(P)-binding domain" CG12030 11-Aug-17 DroID_v2017_08 Drer\gale Scer\GAL10 Cele\gale-1 Xtro\gale Mmus\Gale Hsap\GALE "lethal,recessive,small body,germline clone,viable,chemical sensitive,short lived,chemical conditional,temperature conditional,sterile,heat sensitive,partially lethal - majority die,body color defective" mesothoracic tergum FBgn0001301 kel kelch http://flybase.org/reports/FBgn0001301 - protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 actin binding ; GO:0003779 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from direct assay ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype female germline ring canal formation ; GO:0007301 | inferred from direct assay oogenesis ; GO:0048477 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN001229449 ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype female germline ring canal inner rim ; GO:0035183 | traceable author statement germline ring canal ; GO:0045172 | inferred from direct assay Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from biological aspect of ancestor with PANTHER:PTN001973695 germline ring canal ; GO:0045172 | traceable author statement female germline ring canal ; GO:0035324 | inferred from direct assay "Kel, Dm.Ring_canal/KELC_DROME, Kelch, CG7210, kel, kelch" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR015915:Kelch-type beta propeller" CG7210 11-Aug-17 DroID_v2017_08 "Drer\klhl29, Drer\klhl3, Drer\LOC100334314, Drer\klhl31, Drer\klhl2, Drer\klhl43, Drer\kbtbd8" - "Cele\kel-8, Cele\kel-1, Cele\W07A12.4" - "Mmus\Klhl2, Mmus\Klhl29, Mmus\Kbtbd8, Mmus\Klhl31, Mmus\Klhl3, Mmus\Ccin" "Hsap\KLHL29, Hsap\KLHL2, Hsap\KBTBD8, Hsap\CCIN, Hsap\KLHL31, Hsap\KLHL3" " oogenesis stage && adult stage | female , adult stage | male , adult stage | female " ovary

" adult stage && oogenesis stage , pupal stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage >S1 , larval stage | third instar , adult stage " " egg chamber

, ovary

, germarium region 3 && nurse cell ring canal

, nurse cell ring canal

, imaginal disc

, testis

, ring canal

" "female sterile,recessive,increased cell death,cell shape defective,wild-type" "nurse cell ring canal,egg chamber,nurse cell,nurse cell & actin filament,oocyte & actin filament,nurse cell ring canal rim,oocyte,interfollicle cell,nurse cell fusome,karyosome,nurse cell & nucleus,actin filament,filamentous actin,actin filament & nurse cell ring canal,egg,nurse cell & plasma membrane,inner nurse cell ring canal rim" FBgn0027568 Cand1 Cullin-associated and neddylation-dissociated 1 http://flybase.org/reports/FBgn0027568 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Cul1 inferred from physical interaction with Cul3 negative regulation of protein neddylation ; GO:2000435 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from biological aspect of ancestor with PANTHER:PTN000294436 SCF complex assembly ; GO:0010265 | inferred from biological aspect of ancestor with PANTHER:PTN000294436 regulation of protein stability ; GO:0031647 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000294436 "CG5366, BcDNA:GH07774, Cand1, dmCAND1, CAND1" "IPR011989:Armadillo-like helical, IPR013932:TATA-binding protein interacting (TIP20), IPR016024:Armadillo-type fold" CG5366 11-Aug-17 DroID_v2017_08 "Drer\cand1, Drer\cand2" - Cele\cand-1 "Xtro\cand1, Xtro\cand2" "Mmus\Cand1, Mmus\Cand2" "Hsap\CAND1, Hsap\CAND2" "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0000739 fs(1)A117 female sterile (1) A117 http://flybase.org/reports/FBgn0000739 - gene - - - fs(1)A117 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female semi-sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "egg,embryo" FBgn0259529 GG01317 - http://flybase.org/reports/FBgn0259529 gene - - - GG01317 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0261786 mi minus http://flybase.org/reports/FBgn0261786 protein_coding_gene "protein binding, bridging involved in substrate recognition for ubiquitination ; GO:1990756 | inferred from physical interaction with CycE, Cul1, SkpA, ago" SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype endomitotic cell cycle ; GO:0007113 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype positive regulation of mitotic cell cycle ; GO:0045931 | inferred from mutant phenotype - "mi, CG5360, l(2)SH0818, l(2)SH2 0818" - CG5360 11-Aug-17 DroID_v2017_08 - - - - - - DRSC04498 IK 1.657612351 -1.764990709 -0.614552745 0.378570198 1.509233575 1.77435855 FBgn0038256 CG7530 - http://flybase.org/reports/FBgn0038256 protein_coding_gene receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000465443 - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004254 CG7530 IPR004254:AdipoR/Haemolysin-III-related CG7530 11-Aug-17 DroID_v2017_08 "Drer\paqr8, Drer\paqr4b, Drer\paqr4a, Drer\paqr7b, Drer\paqr5a, Drer\paqr3b, Drer\paqr3a, Drer\paqr6, Drer\paqr7a, Drer\adipor2, Drer\adipor1b, Drer\paqr5b" "Scer\IZH3, Scer\IZH4, Scer\IZH2, Scer\IZH1" Cele\paqr-3 "Xtro\paqr6, Xtro\paqr8, Xtro\adipor1, Xtro\paqr3, Xtro\paqr4, Xtro\paqr5" "Mmus\Paqr9, Mmus\LOC101055651, Mmus\Paqr8, Mmus\Paqr3, Mmus\Paqr7, Mmus\Adipor2, Mmus\Paqr5, Mmus\Adipor1, Mmus\Paqr6, Mmus\Paqr4" "Hsap\PAQR3, Hsap\ADIPOR1, Hsap\PAQR8, Hsap\ADIPOR2, Hsap\PAQR6, Hsap\PAQR4, Hsap\PAQR5, Hsap\PAQR7, Hsap\PAQR9" "chemical resistant,viable" FBgn0052177 Ndfip Nedd4 family interacting protein http://flybase.org/reports/FBgn0052177 protein_coding_gene WW domain binding ; GO:0050699 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with dx inferred from genetic interaction with Su(dx) inferred from genetic interaction with Ser inferred from genetic interaction with N inferred from genetic interaction with Nedd4 wing disc development ; GO:0035220 | inferred from mutant phenotype "late endosome ; GO:0005770 | inferred from direct assay ubiquitin ligase complex ; GO:0000151 | inferred from physical interaction with Su(dx), Smurf, Nedd4" "clone 2.19, anon-EST:Liang-2.19, CG8056, CG32177, Ndfip, dNdfip" - CG32177 11-Aug-17 DroID_v2017_08 "Drer\ndfip1, Drer\ndfip2, Drer\ndfip1l" Scer\BSD2 - "Xtro\ndfip1, Xtro\ndfip2" "Mmus\Ndfip2, Mmus\Ndfip1" "Hsap\NDFIP1, Hsap\NDFIP2" "viable,fertile" "wing margin bristle,supernumerary,wing vein" FBgn0010114 hig hikaru genki http://flybase.org/reports/FBgn0010114 - protein_coding_gene - synaptic target recognition ; GO:0008039 | inferred from mutant phenotype neuronal cell body ; GO:0043025 | inferred from direct assay synaptic cleft ; GO:0043083 | inferred from direct assay "hig, HIG, CT6282, CG2040" "IPR000436:Sushi/SCR/CCP domain, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG2040 11-Aug-17 DroID_v2017_08 "Drer\sez6b, Drer\rca2.1, Drer\rca2.2, Drer\si:ch73-217n20.1, Drer\sez6a, Drer\sez6l2" - Cele\lev-9 "Xtro\sez6l2, Xtro\sez6l" "Mmus\Gm4788, Mmus\F13b, Mmus\Cfhr1, Mmus\Cfh, Mmus\Apoh, Mmus\Sez6l, Mmus\Sez6l2, Mmus\Cfhr2, Mmus\Sez6" "Hsap\CFHR1, Hsap\SEZ6L2, Hsap\CFHR2, Hsap\SEZ6, Hsap\CFH, Hsap\SEZ6L, Hsap\CFHR5, Hsap\APOH, Hsap\CFHR3, Hsap\F13B" " embryonic stage , adult stage , embryonic stage | mid-late , embryonic stage | stage >=10 " " RP neuron

, head

, pCC neuron

, central nervous system | restricted

, supraesophageal ganglion

" "viable,fertile,hypoactive,uncoordinated,locomotor behavior defective,lethal,some die during immature adult stage,recessive,flightless,behavior defective,wild-type" central nervous system DRSC22827 E 0.838339721 0.405379199 1.855433716 0.368394615 -0.249686251 -0.241128801 FBgn0000404 CycA Cyclin A http://flybase.org/reports/FBgn0000404 "FBgn0010826, FBgn0011353, FBgn0044754" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Z600 cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from direct assay cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | non-traceable author statement "regulation of mitotic cell cycle, embryonic ; GO:0009794 | traceable author statement negative regulation of mitotic metaphase/anaphase transition ; GO:0045841 | traceable author statement asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype regulation of chromatin binding ; GO:0035561 | inferred from genetic interaction with Orc2 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of exit from mitosis ; GO:0007096 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement regulation of mitotic nuclear division ; GO:0007088 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | traceable author statement regulation of mitotic cell cycle, embryonic ; GO:0009794 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from genetic interaction with CycB, CycB3 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay spectrosome ; GO:0045170 | inferred from direct assay "cycA, DmcycA, 1449/05, 1329/16, 0545/13, 0521/06, 0245/34, 0104/07, 0046/23, 0040/24, 0033/02, S(rux)3B, l(3)183, rsg11, l(3)rsg11, l(3)neo114, l(3)j3C8, l(3)68Ea, l(3)03946, hari, CG5940, anon-WO0140519.128, CycA, Cyc A, dCycA, CYCA, CLD3" "IPR004367:Cyclin, C-terminal domain, IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like" CG5940 11-Aug-17 DroID_v2017_08 "Drer\ccnb2, Drer\ccno, Drer\ccna2, Drer\ccnb1, Drer\ccna1, Drer\si:ch211-132b12.8" "Scer\CLN3, Scer\CLB3, Scer\CLB5, Scer\CLB2, Scer\CLB6, Scer\CLN2, Scer\CLB4, Scer\CLB1, Scer\CLN1" "Cele\T24A6.1, Cele\T07F10.5, Cele\F08F1.9, Cele\cyb-1, Cele\cya-2, Cele\cya-1, Cele\W05G11.2, Cele\cyb-2.2, Cele\ZK678.3, Cele\T12C9.7, Cele\cyb-2.1" "Xtro\ccna2, Xtro\ccna1, Xtro\ccnf" "Mmus\Ccnb2, Mmus\Ccnb1, Mmus\Ccnf, Mmus\Ccna2, Mmus\Ccna1, Mmus\Ccno" "Hsap\CCNA1, Hsap\CCNB2, Hsap\CCNA2, Hsap\CNTD2, Hsap\CCNF, Hsap\CCNO, Hsap\CCNB1" " oogenesis stage | stage S9-10 && adult stage | female , larval stage , adult stage | female , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage , embryonic stage | early " " nurse cell

, larval brain

, germarium

, ovary

, imaginal disc

, organism

,

ubiquitous " " embryonic stage | early , larval stage , embryonic stage | syncytial blastoderm , embryonic stage " " larval central nervous system

, peripheral nervous system

, imaginal disc

, embryonic central nervous system

" "lethal,recessive,mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during immature adult stage,visible,wild-type,neuroanatomy defective,cell migration defective,viable,reduced" "embryonic/larval dorsal trunk,embryonic/larval transverse connective,ganglion mother cell GMC1-1a,ganglion mother cell GMC4-2a,EL neuron,embryonic epidermis,neuron,mitotic cell cycleprd.RG1,RP2sib neuron,aCC neuron,precursor,pCC neuron,U neuron,larval outer optic anlage,chordotonal organ,neuron & peripheral nervous system,eye,mitotic cell cycle & epidermis & embryo,mitotic cell cycle,egg chamber,S phase | ectopic,amnioserosa,pole cell,egg chamber & cell,egg chamber & mitotic cell cycle,mitotic cell cycle & eye,cell cycle,metaphase & condensed nuclear chromosome,anaphase & condensed nuclear chromosome,embryonic pericardial cell,abdominal segment 2 & cardioblast,abdominal segment 3 & cardioblast,abdominal segment 4 & cardioblast,abdominal segment 5 & cardioblast,abdominal segment 6 & cardioblast,abdominal segment 7 & cardioblast,cardioblast,embryonic/larval glial cell,embryonic/larval tracheal system,embryonic/larval ganglionic branch,embryonic ganglion mother cell,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,neuroblast NB7-3,EW neuron,GW neuron,neuroblast NB6-4 of thorax,neuroblast NB6-4 of abdomen,dorsal neurohemal organ,eye disc,embryonic/larval salivary gland | embryonic stage,nurse cell fusome,S phase | ectopichs.2sev,male germline stem cell,ommatidium,chaeta,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,female germline stem cell,germarium" DRSC11123 IEK -2.114436164 -1.442374368 -0.290036912 -2.217212947 2.826154442 3.090742543 FBgn0000711 flw flapwing http://flybase.org/reports/FBgn0000711 "FBgn0003131, FBgn0029072, FBgn0030197, FBgn0030198, FBgn0066854" protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with protein_id:CAA32941.1 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement myosin phosphatase activity ; GO:0017018 | inferred from direct assay "protein dephosphorylation ; GO:0006470 | non-traceable author statement chromosome segregation ; GO:0007059 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with bsk inferred from genetic interaction with puc imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype mesoderm development ; GO:0007498 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype striated muscle tissue development ; GO:0014706 | inferred from mutant phenotype positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from genetic interaction with Pp1α-96A, Pp1-87B regulation of actomyosin contractile ring contraction ; GO:0031991 | inferred from mutant phenotype beta-catenin destruction complex disassembly ; GO:1904886 | inferred from sequence or structural similarity with UniProtKB:P62139 ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype oocyte nucleus migration involved in oocyte dorsal/ventral axis specification ; GO:0007312 | inferred from mutant phenotype" protein phosphatase type 1 complex ; GO:0000164 | inferred from sequence or structural similarity with protein_id:CAA32941.1 protein phosphatase type 1 complex ; GO:0000164 | colocalizes_with inferred from direct assay "PP1beta9C, flw, PP1, DmPp1-9C, PP1 b9C, PP1c, PP19C, CG2096, FLW/PP1B, Pp1beta-9C, PP1 9C, PP1beta, PP-1, l(1)G0172, CG15305, anon-WO03040301.120, PP1beta-9C, FLW, PP1 beta9c, PP1B_DROME, XE55, Pp1beta9C, PP1cbeta, Pp1-9C" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like, IPR031675:Serine-threonine protein phosphatase, N-terminal" CG2096 11-Aug-17 DroID_v2017_08 "Drer\ppp1cc, Drer\ppp1cb, Drer\ppp1cbl, Drer\ppp1cab, Drer\ppp1caa" "Scer\PPZ2, Scer\PPZ1, Scer\GLC7, Scer\PPQ1" "Cele\gsp-2, Cele\C06A1.3, Cele\F58G1.3, Cele\gsp-4, Cele\gsp-1" "Xtro\ppp1cb, Xtro\ppp1cc" "Mmus\Ppp1cc, Mmus\Ppp1ca, Mmus\Ppp1cb" "Hsap\PPP1CA, Hsap\PPP1CB, Hsap\PPP1CC" embryonic stage -- adult stage pupal stage "increased cell number,recessive,somatic clone,cell polarity defective,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,male,female,lethal,lethal - all die before end of pupal stage,wild-type,flightless,dominant,viable,visible,cell shape defective,locomotor behavior defective,partially lethal - majority live,mitotic cell cycle defective,majority die during larval stage,some die during pupal stage,small body" "nurse cell ring canal,germline clone,oocyte,somatic clone,follicle cell,posterior,egg,maternal effect,wing,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,myofibril,Z disc,indirect flight muscle,adult cuticle & adult thorax,epithelium,egg chamber,actin cytoskeleton,mesothoracic extracoxal depressor muscle 66,embryonic/larval muscle system,posterior crossvein,anterior scutellar bristle,eye,tergosternal muscle 47a,tergosternal muscle 47b,tergosternal muscle 47c,dorsal medial muscle 45c,dorsal medial muscle 45d,dorsal medial muscle 45e,dorsal medial muscle 45f,dorsal medial muscle 45a,dorsal medial muscle 45b,adult thorax,chromosome & larval neuroblast,anaphase,ventral intersegmental muscle,eye disc,wing disc" DRSC18774 I 0.563194382 -2.018698823 0.476967334 -0.306611364 1.024617341 0.538164871 FBgn0000147 aurA aurora A http://flybase.org/reports/FBgn0000147 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVR2 protein serine/threonine/tyrosine kinase activity ; GO:0004712 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay histone serine kinase activity ; GO:0035174 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement" regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype regulation of cellular protein localization ; GO:1903827 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | traceable author statement establishment of spindle orientation ; GO:0051294 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype regulation of cytokinesis ; GO:0032465 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 centrosome separation ; GO:0051299 | inferred from mutant phenotype centrosome cycle ; GO:0007098 | inferred from mutant phenotype mitotic centrosome separation ; GO:0007100 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from direct assay symmetric cell division ; GO:0098725 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 asymmetric protein localization involved in cell fate determination ; GO:0045167 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype "spindle pole centrosome ; GO:0031616 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 cytoplasm ; GO:0005737 | inferred from direct assay spindle microtubule ; GO:0005876 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 centrosome ; GO:0005813 | colocalizes_with inferred from direct assay spindle midzone ; GO:0051233 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 centrosome ; GO:0005813 | non-traceable author statement chromosome passenger complex ; GO:0032133 | inferred from biological aspect of ancestor with PANTHER:PTN000681967" "aurA, CG3068, 87A7-9/2, ck[10], l(3)87Ac, ck10, l(3)ck10, AurA, aur, aur-A, Aur-A, AAK" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR030616:Aurora kinase" CG3068 11-Aug-17 DroID_v2017_08 "Drer\aurkb, Drer\aurka" Scer\IPL1 "Cele\air-1, Cele\air-2" "Xtro\aurka, Xtro\aurkb" "Mmus\Aurkb, Mmus\Aurka, Mmus\Gm7207, Mmus\Aurkc" "Hsap\AURKC, Hsap\AURKB, Hsap\AURKA"

"mitotic cell cycle defective,visible,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,recessive,female sterile,viable,wild-type,somatic clone,sterile,lethal,maternal effect,some die during pharate adult stage,endomitotic cell cycle defective,lethal - all die during P-stage,partially lethal - majority die" "spindle,neuroblast,socket,ectopic,somatic clone,trichogen cell,thecogen cell,eo neuron,tormogen cell,sensory mother cell,centrosome,embryonic/larval neuroblast,embryonic/larval brain,mitotic metaphase & larval brainT-47),mitotic metaphase & larval brainT-61),microtubule & neuroblast & larvaT-61),aster & neuroblast & larvaT-61),centrosome & neuroblast & larvaT-61),centriole & neuroblast & larva | ectopicT-61),mitotic metaphase & larval brainP-79),mitotic metaphase & larval brain,centrosome & neuroblast & larva,macrochaeta,eye,egg chamber,neuroblast | supernumerary & larva,neuroblast | supernumerary & larval brain,supernumerary,spindle & neuroblast & larva,spindle & sensory mother cell & pupa,neuroblast | supernumerary & brain,pole cell,centrosome | embryonic stage,nucleus | embryonic stage,mitotic cell cycle,embryonic/larval central nervous system,subperineurial glial cell,metaphase & condensed nuclear chromosome,aster,microtubule | maternal effect" DRSC16905 IE 2.154148415 0.190328205 0.463149751 -2.094677985 -0.892165187 -0.314323816 FBgn0031654 Jon25Bii Jonah 25Bii http://flybase.org/reports/FBgn0031654 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "25B, CG8869, SP112, Jon25B, Jon25Bii, Jon25" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG8869 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,trichogen cell,mesothoracic tergum" FBgn0041775 tral trailer hitch http://flybase.org/reports/FBgn0041775 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with papi actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | colocalizes_with inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG10686, BEST:GH08269, p67, p70, anon-EST:Posey139, anon-WO0172774.89, anon-WO02059370.24, tral, Tral, Scd6p, TRAL, DmLSm15, LSm15, Lsm15" "IPR025609:Lsm14-like, N-terminal, IPR025768:TFG box, IPR025761:FFD box, IPR019050:FDF domain, IPR025762:DFDF domain, IPR010920:LSM domain" CG10686 11-Aug-17 DroID_v2017_08 "Drer\lsm14aa, Drer\lsm14ab, Drer\lsm14b" Scer\SCD6 Cele\car-1 "Xtro\lsm14a, Xtro\lsm14b" "Mmus\Lsm14a, Mmus\Lsm14b" "Hsap\LSM14A, Hsap\LSM14B" "lethal,female sterile,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal appendage,maternal effect,chorion | anterior,microtubule & oocyte,cycle 12 embryo,cycle 13 embryo,nurse cell,germline clone,egg,chorion | anterioriro-2)" DRSC09779 EK -0.519761582 -0.449039362 -1.804201807 -5.122807187 1.088618331 4.142742509 FBgn0002471 l(3)SG26 lethal (3) SG26 http://flybase.org/reports/FBgn0002471 FBgn0004712 gene - - - "l(3)ds-2, l(3)g26, l(3)ds2, l(3)B2, l(3)SG26" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,imaginal disc primordium,testis,ovary,central nervous system,mitotic cell cycle" FBgn0051371 CG31371 - http://flybase.org/reports/FBgn0051371 protein_coding_gene "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR013547 endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG15542, CG31371" "IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG31371 11-Aug-17 DroID_v2017_08 "Drer\zgc:158254, Drer\p4ha1a, Drer\zgc:152670, Drer\p4htm, Drer\p4ha1b, Drer\p4ha3, Drer\p4ha2" - "Cele\Y43F8B.19, Cele\C14E2.4, Cele\phy-3, Cele\phy-4, Cele\phy-2" "Xtro\p4ha3, Xtro\p4ha1, Xtro\p4ha2" "Mmus\P4ha1, Mmus\P4ha2, Mmus\P4htm, Mmus\P4ha3" "Hsap\P4HA1, Hsap\P4HTM, Hsap\P4HA3, Hsap\P4HA2" viable FBgn0003185 qrt quartet http://flybase.org/reports/FBgn0003185 FBgn0004728 gene - - - "l(3)ds-1, l(3)C21, l(3)c21R, l(3)c21r, l(3)ds1, l(3)SG56, l(3)CR215, l(3)B1, qrt" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,maternal effect,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage" "imaginal disc,eye-antennal disc,ventral thoracic disc,haltere disc,genital disc,centrosome | maternal effect | heat sensitive,spindle | maternal effect | heat sensitive,mitosis & nuclear chromosome | conditional ts | maternal effect,embryo,nucleus | embryonic stage | maternal effect | heat sensitive" FBgn0026398 Or22a Odorant receptor 22a http://flybase.org/reports/FBgn0026398 - protein_coding_gene "olfactory receptor activity ; GO:0004984 | inferred from direct assay transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model olfactory receptor activity ; GO:0004984 | non-traceable author statement inferred by curator from GO:0004888,GO:0007608 olfactory receptor activity ; GO:0004984 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b" sensory perception of smell ; GO:0007608 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from expression pattern sensory perception of smell ; GO:0007608 | inferred by curator from GO:0004984 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from direct assay sensory dendrite ; GO:0071683 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "Or22a, 22a, DOR22a, DOR53, CG12193, AN11, 22A.1, Dor53, dor53, DOR22A.1, Or53, Or22A.1, OR22a, Dmel Or22a, Dmel22a, dOr22a, Or22a/b, DmOr22a, Or22" "IPR004117:Olfactory receptor, insect, IPR023298:P-type ATPase, transmembrane domain" CG12193 11-Aug-17 DroID_v2017_08 - Scer\RIF2 - - - - adult stage sensory neuron &&of antennal segment 3

neurophysiology defective olfactory receptor neuron FBgn0016081 fry furry http://flybase.org/reports/FBgn0016081 "FBgn0010771, FBgn0036021, FBgn0036025, FBgn0036027, FBgn0052045" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with trc "oocyte morphogenesis ; GO:0048601 | inferred from direct assay regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype non-sensory hair organization ; GO:0035316 | inferred from mutant phenotype positive regulation of protein kinase activity ; GO:0045860 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with trc dendrite self-avoidance ; GO:0070593 | inferred from genetic interaction with stan Wnt signaling pathway ; GO:0016055 | NOT inferred from genetic interaction with mwh imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype actin filament reorganization ; GO:0090527 | inferred from biological aspect of ancestor with PANTHER:PTN000265604 antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype" axon ; GO:0030424 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay cell body ; GO:0044297 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay site of polarized growth ; GO:0030427 | inferred from biological aspect of ancestor with PANTHER:PTN000265604 apical part of cell ; GO:0045177 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "l(3)02240, SS3-7, yeti, CG6780, CG6774, CG14171, CG32045, fry, Fry, RE-B" "IPR025614:Cell morphogenesis protein N-terminal, IPR025481:Cell morphogenesis protein C-terminal, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR029473:Cell morphogenesis central region" CG32045 11-Aug-17 DroID_v2017_08 "Drer\fryl, Drer\fryb, Drer\frya" Scer\TAO3 Cele\sax-2 Xtro\fryl "Mmus\Fry, Mmus\Fryl" "Hsap\FRYL, Hsap\FRY" "viable,fertile,neuroanatomy defective,visible,lethal,recessive,cell autonomous,somatic clone,lethal - all die before end of larval stage,some die during larval stage,sterile,poor" "multidendritic neuron & dendrite | supernumerary,multidendritic neuron & dendrite,dorsal multidendritic neuron ddaC,arista,wing hair,supernumerary,adult abdomen & chaeta,leg & chaeta,mesothoracic tergum & chaeta,triple row,head bristle,cell autonomous,somatic clone,wing cell,ectopic,ovary,egg,rhabdomere,dendrite | cell autonomous | somatic clone | supernumerary,multidendritic neuron & dendrite | somatic clone,photoreceptor cell & eye disc | somatic clone,follicle cell,actin filament | somatic clone,egg chamber" DRSC10709 K 0.348784729 -0.805535142 -0.35183424 0.22606273 0.863359078 1.691806549 FBgn0011737 Wee1 Wee1 kinase http://flybase.org/reports/FBgn0011737 FBgn0010519 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR017164 non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from electronic annotation with InterPro:IPR017164 protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P46863 protein kinase activity ; GO:0004672 | non-traceable author statement" mitotic nuclear division ; GO:0007067 | inferred from electronic annotation with InterPro:IPR017164 embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement negative regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045736 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype negative regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045736 | inferred from direct assay centrosome localization ; GO:0051642 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay spindle assembly ; GO:0051225 | inferred from mutant phenotype peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement mitotic cell cycle checkpoint ; GO:0007093 | inferred from direct assay centrosome separation ; GO:0051299 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Wee1, dwee1, Dwee, wee1, Dwee1, Wee 1, dWee1, WEE1, CG4488, Wee, wee" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR017164:Wee1-like protein kinase, IPR017441:Protein kinase, ATP binding site" CG4488 11-Aug-17 DroID_v2017_08 "Drer\pkmyt1, Drer\wee2, Drer\wee1" "Scer\SSK2, Scer\SWE1" "Cele\wee-1.3, Cele\wee-1.1" "Xtro\pkmyt1, Xtro\wee2" "Mmus\Wee2, Mmus\Pkmyt1, Mmus\Wee1" "Hsap\WEE1, Hsap\WEE2, Hsap\PKMYT1" " embryonic stage | stage 14 , embryonic stage | stage 14-17 , embryonic stage | stage 6 , embryonic stage | stage 7 , larval stage | first instar , embryonic stage | , embryonic/larval midgut

, embryonic/larval hindgut

, embryonic central nervous system

, pole cell

, mesoderm anlage

, larval brain

, organism | ubiquitous

" "female sterile,recessive,wild-type,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,visible,mitotic cell cycle defective,chemical sensitive,male fertile,non-rescuable maternal effect,viable" "nucleus | embryonic cycle 12,ommatidium,wing margin,chaeta & adult thorax | dorsalap-md544,wing,scutellum,chaeta & adult thorax | dorsalpnr-MD237,adult thorax,interommatidial bristle,mitotic cell cycleunspecified,anaphase & centrosome & cycle 13 embryo | maternal effect,anaphase & centrosome & cycle 12 embryo | maternal effect,spindle | embryonic cycle 13 | maternal effect,spindle | embryonic cycle 12 | maternal effect,microtubule organizing center | embryonic cycle 13 | maternal effect,microtubule organizing center | embryonic cycle 12 | maternal effect,interphase & centrosome & cycle 12 embryo | maternal effect,metaphase & centrosome & cycle 12 embryo | maternal effect,nucleus | ectopic | embryonic stage 4 | maternal effect,mitotic interphase | maternal effect,mitotic anaphase | embryonic cycle 12 | maternal effect,mitotic telophase | embryonic cycle 12 | maternal effect,aster | embryonic cycle 12 | maternal effect,aster | embryonic cycle 13 | maternal effect,anaphase & condensed nuclear chromosome & cycle 13 embryo | maternal effect,mitotic cell cycle,nucleus | embryonic cycle 11" FBgn0011278 lbe ladybird early http://flybase.org/reports/FBgn0011278 FBgn0010394 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" "epidermis development ; GO:0008544 | inferred from mutant phenotype skeletal muscle tissue development ; GO:0007519 | inferred from genetic interaction with lbl heart development ; GO:0007507 | traceable author statement regulation of neuron differentiation ; GO:0045664 | inferred from mutant phenotype regulation of cell fate specification ; GO:0042659 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from expression pattern regulation of myoblast fusion ; GO:1901739 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from genetic interaction with lbl myoblast proliferation ; GO:0051450 | inferred from genetic interaction with lbl genital disc morphogenesis ; GO:0007483 | inferred from mutant phenotype mesodermal cell fate specification ; GO:0007501 | traceable author statement neuron development ; GO:0048666 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from genetic interaction with lbl muscle organ development ; GO:0007517 | inferred from mutant phenotype central nervous system development ; GO:0007417 | non-traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype muscle organ development ; GO:0007517 | traceable author statement cell migration ; GO:0016477 | inferred from genetic interaction with lbl dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Lbe, lb, Lb, Hox11-D125, NK?, CG6545, lbe" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG6545 11-Aug-17 DroID_v2017_08 "Drer\tlx3b, Drer\lbx1b, Drer\ved, Drer\barx1, Drer\barhl2, Drer\pnx, Drer\hlx1, Drer\nkx1.2lb, Drer\vox, Drer\LOC100008066, Drer\barhl1b, Drer\lbx2, Drer\lbx1a, Drer\tlx2, Drer\barx2, Drer\dbx1b, Drer\tlx1" - - "Xtro\hlx, Xtro\nkx1-1, Xtro\tlx3, Xtro\tlx2, Xtro\barhl2, Xtro\ventx1.2, Xtro\nkx1-2, Xtro\lbx1, Xtro\barhl1, Xtro\tlx1, Xtro\dbx1, Xtro\barx1" "Mmus\Dbx2, Mmus\Tlx3, Mmus\Barx2, Mmus\Hlx, Mmus\Nkx1-2, Mmus\Barhl2, Mmus\Nkx1-1, Mmus\Lbx2, Mmus\Barx1, Mmus\Tlx2, Mmus\Barhl1, Mmus\Lbx1, Mmus\Dbx1, Mmus\Tlx1" "Hsap\LBX1, Hsap\HOXB7, Hsap\LBX2, Hsap\BARX2, Hsap\DBX1, Hsap\TLX2, Hsap\TLX3, Hsap\TLX1, Hsap\BARHL2, Hsap\HOXB9, Hsap\HOXD9, Hsap\HOXC10, Hsap\HLX, Hsap\HOXC9, Hsap\HOXC5, Hsap\DBX2, Hsap\NKX1-1, Hsap\HOXA9, Hsap\BARX1, Hsap\BARHL1" " embryonic stage | late , embryonic stage | stage 10-11 , embryonic stage | stage 13 , embryonic stage | stage 10-13 , embryonic stage | stage 15 , embryonic stage | stage 11 " " central nervous system | restricted

, embryonic neuroblast

, ectoderm | ventral

, dorsal ectoderm &&of abdominal segment 1--7

, embryonic peripheral nervous system | restricted

, segment border muscle

, epidermis | dorsal

, epidermis | segmentally repeated

" " embryonic stage | stage 13 , embryonic stage | stage 9-11 , embryonic stage | stage 10-13 , embryonic stage | stage 10-11 , embryonic stage | stage 15 , embryonic stage | late , embryonic stage | stage >8 " " ectoderm | ventral

, tritocerebral neuroblast | subset

, dorsal ectoderm &&of abdominal segment 1--7

, deuterocerebral neuroblast | subset

, ectoderm &&of embryonic gnathal segment

, protocerebral neuroblast | subset

, epidermis | dorsal

, embryonic peripheral nervous system | restricted

, anal pad | primordium

, central nervous system | restricted

, segment border muscle

, procephalic neurogenic region | restricted

" "locomotor behavior defective,lethal,viable" "embryonic/larval pericardial cell,embryonic cardioblast,embryonic/larval somatic muscle,adult heart,adult heart muscle,embryonic/larval dorsal vessel,precursor,dorsal denticle,EL neuron,central nervous system,exit glial cell,ectopic,glial cell,intersegmental nerve,prothoracic segmental nerve,segment border muscle,abdominal 1 lateral adult muscle precursor cell,abdominal 2 lateral adult muscle precursor cell,abdominal 3 lateral adult muscle precursor cell,abdominal 4 lateral adult muscle precursor cell,abdominal 5 lateral adult muscle precursor cell,abdominal 6 lateral adult muscle precursor cell,abdominal 7 lateral adult muscle precursor cell,abdominal 1 ventral adult muscle precursor cell,abdominal 2 ventral adult muscle precursor cell,abdominal 3 ventral adult muscle precursor cell,abdominal 4 ventral adult muscle precursor cell,abdominal 5 ventral adult muscle precursor cell,abdominal 6 ventral adult muscle precursor cell,abdominal 7 ventral adult muscle precursor cell,lateral,A1-7 dorsal acute muscle 1,A1-7 dorsal oblique muscle 1,cardiac outflow muscle,aorta primordium,muscle fiber,myoblast,tarsal levator muscle,dorsal acute muscle 1,dorsal transverse muscle,ventral acute muscle 2,nucleus | supernumerarykirre.PR" FBgn0039283 danr distal antenna-related http://flybase.org/reports/FBgn0039283 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O18381 inferred from physical interaction with UniProtKB:Q24027 inferred from physical interaction with UniProtKB:Q9VBW6" "compound eye development ; GO:0048749 | inferred from mutant phenotype antennal development ; GO:0007469 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype central nervous system formation ; GO:0021556 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "CG13651, danr, Danr, hern" "IPR009057:Homeobox domain-like, IPR007889:DNA binding HTH domain, Psq-type, IPR011991:Winged helix-turn-helix DNA-binding domain" CG13651 11-Aug-17 DroID_v2017_08 - - - Xtro\tigd5 Mmus\Tigd4 "Hsap\TIGD4, Hsap\TIGD5" " pupal stage | early , larval stage | third instar " " eye-antennal disc | restricted

, antennal disc | restricted & central

, eye disc | restricted

" "visible,viable,neuroanatomy defective,lethal" "tarsal segment,third segment of antenna,basal cylinder,somatic clone,bract,ectopic,antennal segment 3 & macrochaeta | ectopicDll-md23,arista,eye,ommatidium,interommatidial bristle,ventral nerve cord,presumptive embryonic/larval nervous system,germ band,leg,distal,antenna,unguis,rostral membrane,wing,wing margin bristle" FBgn0034180 Ehbp1 Eps15 homology domain containing protein-binding protein 1 http://flybase.org/reports/FBgn0034180 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity sensory organ precursor cell division ; GO:0045035 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "dEHBP1, CG15609, Ehbp1, 2R11, dEHBP-1, EHBP1" "IPR019448:EEIG1/EHBP1 N-terminal domain, IPR001715:Calponin homology domain, IPR022735:Domain of unknown function DUF3585" CG15609 11-Aug-17 DroID_v2017_08 "Drer\ehbp1, Drer\ehbp1l1b, Drer\smtna, Drer\spna2, Drer\specc1la, Drer\actn4, Drer\smtnl, Drer\specc1, Drer\actn3a, Drer\LOC558044, Drer\sptbn1, Drer\actn3b, Drer\zgc:165653, Drer\otx1b, Drer\ehbp1l1a, Drer\specc1lb, Drer\sptb, Drer\actn2b" - Cele\ehbp-1 "Xtro\ehbp1l1, Xtro\actn2, Xtro\actn3, Xtro\sptbn2, Xtro\sptbn5, Xtro\actn4, Xtro\sptan1, Xtro\smtn, Xtro\actn1, Xtro\ehbp1" "Mmus\Sptbn4, Mmus\Spta1, Mmus\Sptan1, Mmus\Ehbp1l1, Mmus\Specc1l, Mmus\Sptbn2, Mmus\Actn3, Mmus\Actn1, Mmus\Actn4, Mmus\Actn2, Mmus\Sptbn1, Mmus\Smtnl2, Mmus\Ehbp1, Mmus\Smtnl1" "Hsap\SPTBN4, Hsap\SPECC1L, Hsap\SPTBN1, Hsap\SPTAN1, Hsap\ACTN4, Hsap\SPTA1, Hsap\SPTBN5, Hsap\SMTNL2, Hsap\EHBP1L1, Hsap\ACTN1, Hsap\ACTN2, Hsap\SMTN, Hsap\EHBP1, Hsap\SPTBN2" "visible,body color defective,partially lethal - majority die,some die during pupal stage,somatic clone,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,recessive,lethal" "mesothoracic tergum,chaeta,somatic clone" FBgn0025615 Torsin Torsin http://flybase.org/reports/FBgn0025615 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR010448, InterPro:IPR017378 ATPase activity ; GO:0016887 | inferred from sequence model ATP binding ; GO:0005524 | inferred from sequence model" chaperone mediated protein folding requiring cofactor ; GO:0051085 | inferred from electronic annotation with InterPro:IPR017378 positive regulation of GTP cyclohydrolase I activity ; GO:0043104 | inferred from mutant phenotype negative regulation of phosphatidate phosphatase activity ; GO:1903741 | inferred from mutant phenotype membrane lipid biosynthetic process ; GO:0046467 | inferred from mutant phenotype larval fat body development ; GO:0007504 | inferred from mutant phenotype ribonucleoprotein complex export from nucleus ; GO:0071426 | inferred from mutant phenotype regulation of dopamine metabolic process ; GO:0042053 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype cellular lipid metabolic process ; GO:0044255 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype nuclear envelope ; GO:0005635 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "Torp4a, DmTorp4a, EG:84H4.1, CG3024, torp4a, TORP4A, Torsin, dtor, torsin, dtorsin, DTor" "IPR010448:Torsin, IPR017378:Torsin 1/2, IPR030553:Torsin-like protein, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3024 11-Aug-17 DroID_v2017_08 "Drer\tor4ab, Drer\tor4aa, Drer\tor1l3, Drer\tor1, Drer\tor1l2, Drer\tor3a, Drer\tor2a, Drer\tor1l1, Drer\LOC101886311" - "Cele\ooc-5, Cele\tor-2, Cele\tor-1" "Xtro\tor3a, Xtro\tor1b, Xtro\tor2a, Xtro\tor4a, Xtro\tor1a" "Mmus\Tor3a, Mmus\Tor2a, Mmus\Tor1b, Mmus\Tor1a, Mmus\Tor4a" "Hsap\TOR2A, Hsap\TOR1B, Hsap\TOR1A, Hsap\TOR4A, Hsap\TOR3A" "partially lethal - majority die,male sterile,body color defective,locomotor behavior defective,neuroanatomy defective,viable" "chaeta,dopaminergic neuron,NMJ bouton,NMJ bouton | third instar larval stage" FBgn0260066 2L3642 - http://flybase.org/reports/FBgn0260066 gene - - - 2L3642 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0002633 E(spl)m7-HLH "Enhancer of split m7, helix-loop-helix" http://flybase.org/reports/FBgn0002633 "FBgn0020009, FBgn0020922" protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement transcription factor binding ; GO:0008134 | inferred from genetic interaction with gro inferred from genetic interaction with sc inferred from genetic interaction with da transcription factor binding ; GO:0008134 | inferred from physical interaction with gro sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" brain morphogenesis ; GO:0048854 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok compound eye development ; GO:0048749 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype - "CG8361, m7, HLHm7, E(spl)m7, ESPL, M7, E(spl) m7, E(spl)-m7, E(spl)M7, E(spl)-M7, E(SPL)m7, HLH-m7, En(spl)m7, bHLHb35, HlHm7, E(spl)m7-HLH" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8361 11-Aug-17 DroID_v2017_08 "Drer\ube2t, Drer\ttc19, Drer\her1, Drer\bicc2, Drer\klc2, Drer\her5, Drer\LOC100149863, Drer\vrk2, Drer\ube2d4, Drer\heyl, Drer\ube2nb, Drer\csnk1a1, Drer\csnk1e, Drer\nphp3, Drer\ube2e2, Drer\ttbk2b, Drer\her9, Drer\her4.4, Drer\csnk1db, Drer\her4.2, Drer\bicc1b, Drer\hdlbpb, Drer\bhlhe40, Drer\bhlhe41, Drer\her13, Drer\her8.2, Drer\her4.3, Drer\ube2d3, Drer\ube2e3, Drer\helt, Drer\bicc1a, Drer\her11, Drer\hdlbpa, Drer\her8a, Drer\her6, Drer\vrk1, Drer\hes2.1, Drer\her7, Drer\her15.1, Drer\klc4, Drer\ube2d2, Drer\ube2d1b, Drer\her3, Drer\her2, Drer\ube2na, Drer\ttbk1b, Drer\her12, Drer\ttbk1a, Drer\hes6, Drer\vrk3, Drer\hey1, Drer\appbp2, Drer\hes2.2, Drer\hey2, Drer\csnk1da, Drer\her15.2, Drer\ube2e1, Drer\klc1a, Drer\klc3, Drer\ube2d1a" "Scer\PEX4, Scer\ATG7, Scer\SCP160, Scer\HRR25, Scer\UBC4, Scer\UBC13, Scer\PHO4, Scer\YLL032C, Scer\UBC5" "Cele\hlh-27, Cele\lin-22, Cele\hlh-25" "Xtro\bhlhe40, Xtro\hes7.1, Xtro\ube2d3, Xtro\vrk3, Xtro\hes1, Xtro\bhlhe41, Xtro\hes2, Xtro\hey1, Xtro\bicc1, Xtro\appbp2, Xtro\ube2e2, Xtro\ttc19, Xtro\hes6.2, Xtro\hey2, Xtro\csnk1e, Xtro\hes6.1, Xtro\csnk1a1, Xtro\nphp3, Xtro\ube2e1, Xtro\vrk2, Xtro\hdlbp, Xtro\vrk1, Xtro\ube2d4, Xtro\ube2n, Xtro\csnk1d, Xtro\anks6, Xtro\ttbk2, Xtro\ube2d1, Xtro\hes7.2, Xtro\hes4, Xtro\klc1, Xtro\ube2e3" "Mmus\Ttbk2, Mmus\Anks6, Mmus\Hes3, Mmus\Klc4, Mmus\Appbp2, Mmus\Heyl, Mmus\Klc2, Mmus\Csnk1a1, Mmus\Ube2n, Mmus\Vrk1, Mmus\Nphp3, Mmus\Helt, Mmus\Ube2dnl2, Mmus\Ube2e3, Mmus\Klc1, Mmus\Ube2d1, Mmus\Gm382, Mmus\Ube2e2, Mmus\Hdlbp, Mmus\Hey2, Mmus\Ube2e1, Mmus\Bhlhe40, Mmus\Atg7, Mmus\Vrk3, Mmus\Bicc1, Mmus\Ttc19, Mmus\Ube2dnl1, Mmus\Csnk1d, Mmus\Hey1, Mmus\Ube2d2b, Mmus\Ube2t, Mmus\Hes6, Mmus\Vrk2, Mmus\Ttbk1, Mmus\Bhlhe41, Mmus\Csnk1e, Mmus\Hes5, Mmus\Hes7, Mmus\Klc3, Mmus\Hes2, Mmus\Hes1, Mmus\Ube2d3" "Hsap\VRK1, Hsap\UBE2D4, Hsap\HES1, Hsap\UBE2E3, Hsap\HDLBP, Hsap\ATG7, Hsap\HEY1, Hsap\NPHP3, Hsap\HEYL, Hsap\UBE2D3, Hsap\TTBK2, Hsap\VRK3, Hsap\ANKS6, Hsap\CSNK1D, Hsap\BHLHE40, Hsap\HEY2, Hsap\CSNK1E, Hsap\HES6, Hsap\UBE2NL, Hsap\TTBK1, Hsap\HES2, Hsap\UBE2E1, Hsap\HES5, Hsap\UBE2D1, Hsap\VRK2, Hsap\UBE2T, Hsap\KLC4, Hsap\APPBP2, Hsap\UBE2D2, Hsap\CSNK1A1, Hsap\KLC3, Hsap\HES7, Hsap\CSNK1A1L, Hsap\UBE2N, Hsap\TTC19, Hsap\BICC1, Hsap\KLC1, Hsap\HES3, Hsap\HELT, Hsap\KLC2, Hsap\BHLHE41, Hsap\HES4, Hsap\UBE2E2" " embryonic stage | stage 11-14 , embryonic stage | stage 5 , embryonic stage | 6-10 hr , embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | stage 7-11 , embryonic stage | stage 11-12 " " stomatogastric nervous system | primordium

, vitellophage

, supraesophageal ganglion

, epidermis | restricted

, ectoderm

, posterior midgut proper primordium

, mesoderm

, organism | striped

, optic lobe | primordium

" "visible,viable,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective" "chaeta,mesothoracic tergum,macrochaeta,microchaeta,adult thorax,ectopic,scutum & macrochaetah-1J3,wing & macrochaetaptc-559.1,scutum & macrochaetaptc-559.1,wing,scutum,campaniform sensillum of anterior crossvein,leg & macrochaeta30A,wing & macrochaeta69B,wing vein,dorsal mesothoracic disc & sensory mother cell455.2,sensory mother cell,wing & sensory mother cell455.2,eye,interommatidial bristle,scutellar bristle,adult mesothoracic segment,scutellum & macrochaetah-1J3,wing vein L2,wing vein L4,wing margin bristle,scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,mesothoracic tergum & macrochaeta-C253,anterior wing margin,intersegmental nerve" FBgn0004510 Ets97D Ets at 97D http://flybase.org/reports/FBgn0004510 FBgn0003727 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418, InterPro:IPR003118 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000218930" "mitochondrion organization ; GO:0007005 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype glutamine metabolic process ; GO:0006541 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 regulation of mitochondrion organization ; GO:0010821 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000218930 "Ets, D-elg, elg, DELG, D-Elg, tny, tne, Elg, CG6338, Ets97D, d-elg, Delg, delg" "IPR000418:Ets domain, IPR003118:Pointed domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR013761:Sterile alpha motif/pointed domain, IPR016312:Transcription factor, GA-binding, alpha subunit, IPR024668:GA-binding protein alpha subunit, N-terminal" CG6338 11-Aug-17 DroID_v2017_08 "Drer\elk3, Drer\fev, Drer\elk4, Drer\elk1, Drer\gabpa, Drer\fli1b, Drer\LOC100537796, Drer\erf, Drer\etv1, Drer\etv2, Drer\fli1a, Drer\ets2, Drer\etv5a, Drer\erfl3, Drer\etv4, Drer\etv5b, Drer\erg" - "Cele\ets-4, Cele\elf-1, Cele\tag-97" "Xtro\elk3, Xtro\ets2, Xtro\etv3, Xtro\erf, Xtro\etv2, Xtro\ets1, Xtro\erg, Xtro\elk4, Xtro\gabpa, Xtro\elk1, Xtro\etv1" "Mmus\Ets2, Mmus\Etv1, Mmus\Etv2, Mmus\Elk1, Mmus\Fev, Mmus\Erg, Mmus\Elk3, Mmus\Erf, Mmus\Etv3, Mmus\Gabpa, Mmus\Etv4, Mmus\Elk4, Mmus\Ets1, Mmus\Etv5, Mmus\Fli1" "Hsap\FEV, Hsap\ETV5, Hsap\GABPA, Hsap\ETV4, Hsap\ETS1, Hsap\FLI1, Hsap\ELK1, Hsap\ERG, Hsap\ERF, Hsap\ETS2, Hsap\ETV3L, Hsap\ELK3, Hsap\ETV2, Hsap\ETV1, Hsap\ETV3, Hsap\ELK4" embryonic stage "

ubiquitous , pole cell

" "wild-type,female sterile,lethal,recessive,developmental rate defective,viable,visible,partially lethal - majority die,some die during pupal stage" "chorion,dorsal appendage,egg,nurse cell & nuclear chromosome,follicle cell,fat body,mitochondrion,mitochondrial chromosome,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,egg chamber,germline clone,border follicle cell,trichogen cell" DRSC27682 K -0.590114826 0.114597255 -0.022913361 0.106784789 0.432117482 -1.844911779 FBgn0002336 l(3)87Be lethal (3) 87Be http://flybase.org/reports/FBgn0002336 - gene - - - "0643/07, 0545/01, ck17, l(3)ck17, l(3)87Be" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0069337 UY2506 UY2506 http://flybase.org/reports/FBgn0069337 gene - - - UY2506 - - 11-Aug-17 DroID_v2017_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell,mushroom body alpha-lobe,mushroom body beta-lobe" FBgn0053500 CG33500 - http://flybase.org/reports/FBgn0053500 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33500 - CG33500 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" DRSC09115 K 1.714254629 1.483153396 FBgn0020914 Outspan Outspan http://flybase.org/reports/FBgn0020914 - gene - - - Outspan - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0061496 l(2)45Aq lethal (2) 45Aq http://flybase.org/reports/FBgn0061496 gene - - - l(2)45Aq - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263894 D40 - http://flybase.org/reports/FBgn0263894 gene - - - D40 - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0002981 Oce Ocellarless http://flybase.org/reports/FBgn0002981 - gene - - - Oce - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,fertile,dominant" "ocellar bristle,postvertical bristle,macrochaeta,scutellar bristle,wing,ocellus,head & macrochaeta,wing vein L5,posterior crossvein" FBgn0010015 CanA1 Calcineurin A1 http://flybase.org/reports/FBgn0010015 "FBgn0004466, FBgn0005780" protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006186 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity calcium-dependent protein serine/threonine phosphatase activity ; GO:0004723 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement" response to nitric oxide ; GO:0071731 | inferred from direct assay medium-term memory ; GO:0072375 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity sleep ; GO:0030431 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement regulation of innate immune response ; GO:0045088 | inferred from direct assay protein dephosphorylation ; GO:0006470 | non-traceable author statement calcineurin complex ; GO:0005955 | inferred from sequence or structural similarity synaptic vesicle ; GO:0008021 | non-traceable author statement "DmCanA1-100B, canA, CG1455, CAN A1/PP2B, pMY4, CNA1, PP2B, PP2B 21EF, CnnA21EF, D14, PpD14, Can, CanA1, CnA, Cana1, canA1" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG1455 11-Aug-17 DroID_v2017_08 "Drer\ppp3cca, Drer\ppp3ccb, Drer\ppp3ca, Drer\ppp3cb" "Scer\CMP2, Scer\CNA1" Cele\tax-6 "Xtro\ppp3cb, Xtro\ppp3ca, Xtro\ppp3cc" "Mmus\Ppp3cc, Mmus\Ppp3ca, Mmus\Ppp3cb" "Hsap\PPP3CA, Hsap\PPP3CC, Hsap\PPP3CB" "sleep defective,locomotor behavior defective,partially lethal - majority die,some die during pupal stage,visible,memory defective,hypoactive" "trichogen cell,mesothoracic tergum" FBgn0026418 Hsc70Cb Hsc70Cb http://flybase.org/reports/FBgn0026418 "FBgn0010707, FBgn0010924, FBgn0013562, FBgn0026569, FBgn0027982, FBgn0028258, FBgn0028259, FBgn0062110" protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "Hsc70, HSC-70, HSC70, l(3)70Ca, l(3)148513, l(3)134217, hsc70Cb, l(3)00082, l(3)70Cb, l(3)07621, LD32772, 1485/13, 1348/02, 1342/17, 0318/20, 0041/12, l(3)S148513, l(3)S134802, l(3)S134217, CG6603, BEST:LD32772, anon-WO0118547.302, Hsc70Cb, HSP110-1, hsc70cb, HSC70cb, dHsp110, HSP110, Hsp100" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG6603 11-Aug-17 DroID_v2017_08 "Drer\hsph1, Drer\hspa4b, Drer\hspa4l, Drer\hspa4a" "Scer\SSE1, Scer\SSE2" Cele\hsp-110 "Xtro\hsph1, Xtro\hspa4" "Mmus\Hsph1, Mmus\Hspa4, Mmus\Hspa4l" "Hsap\HSPH1, Hsap\HSPA4L, Hsap\HSPA4" larval stage | third instar " embryonic/larval proventriculus

, larval brain

, embryonic/larval salivary gland

, embryonic/larval midgut

, embryonic/larval hindgut

, imaginal disc

, Malpighian tubule

, gastric caecum

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "arista,trichogen cell,mesothoracic tergum" DRSC26538 K -0.366952366 -0.421282707 -0.365583218 0.31177533 1.832017136 0.193143432 FBgn0003744 trc tricornered http://flybase.org/reports/FBgn0003744 "FBgn0014866, FBgn0028111" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8IQG1 ATP binding ; GO:0005524 | inferred from sequence or structural similarity with UniProtKB:Q15208 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:17847 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with UniProtKB:Q15208 protein binding ; GO:0005515 | inferred from physical interaction with fry protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay intracellular signal transduction ; GO:0035556 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement signal transduction ; GO:0007165 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from sequence or structural similarity with UniProtKB:Q15208 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:17847 dendrite self-avoidance ; GO:0070593 | inferred from genetic interaction with stan imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:Q15208 regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cell periphery ; GO:0071944 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cell body ; GO:0044297 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q15208 axon ; GO:0030424 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:17847 cell hair ; GO:0070451 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "dmTRC, NDR, CG8637, Ndr, 0669/17, l(3)S066917, trc, Trc, RE-D, l(3)76BDa" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG8637 11-Aug-17 DroID_v2017_08 "Drer\lats2, Drer\stk38a, Drer\stk38l, Drer\lats1, Drer\stk38b" "Scer\DBF2, Scer\CBK1, Scer\DBF20" "Cele\sax-1, Cele\snt-5, Cele\wts-1" "Xtro\stk38, Xtro\lats2, Xtro\stk38l" "Mmus\Stk38l, Mmus\Lats1, Mmus\Stk38, Mmus\Lats2, Mmus\Dmpk" "Hsap\STK38, Hsap\LATS1, Hsap\DMPK, Hsap\LATS2, Hsap\STK38L" "visible,somatic clone,lethal,recessive,cell shape defective,lethal - all die before end of embryonic stage,some die during embryonic stage,developmental rate defective,viable,planar polarity defective,neuroanatomy defective,female fertile,lethal - all die before end of pupal stage,some die during pupal stage" "multidendritic neuron & dendrite | supernumerary477,multidendritic neuron & dendrite477,wing hair,somatic clone,supernumerary,arista,cell autonomous,denticle,antenna,arista lateral,wing,trichome,macrochaeta,trichogen cell,adult abdominal sensillum,dendritic arborizing neuron,dendrite,denticle belt,multidendritic neuron & dendrite | supernumerary,multidendritic neuron & dendrite,dendrite | cell autonomous | somatic clone | supernumerary,multidendritic neuron & dendrite | somatic clone,egg,dorsal multidendritic neuron ddaC,follicle cell,actin filament | somatic clone,egg chamber" FBgn0010288 Uch Ubiquitin carboxy-terminal hydrolase http://flybase.org/reports/FBgn0010288 - protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR001578 protein deubiquitination ; GO:0016579 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000063280 microtubule associated complex ; GO:0005875 | inferred from direct assay "UCH, UCH-D, UBL, uch, uch-D, CG4265, Uch, UCH-D19, Uch-D, dUch, P35122, Uchl1" "IPR001578:Peptidase C12, ubiquitin carboxyl-terminal hydrolase" CG4265 11-Aug-17 DroID_v2017_08 "Drer\uchl3, Drer\uchl1" Scer\YUH1 "Cele\ubh-3, Cele\ubh-1, Cele\ubh-2" "Xtro\uchl3, Xtro\uchl1" "Mmus\Uchl4, Mmus\Uchl1, Mmus\Uchl3" "Hsap\UCHL1, Hsap\UCHL3" " adult stage && oogenesis stage , spermatogenesis && adult stage " " nurse cell

, oocyte

, spermatocyte

" "viable,fertile" FBgn0029003 mab-21 mab-21 http://flybase.org/reports/FBgn0029003 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4746, mab-21, mab-2" "IPR024810:Mab-21 domain, IPR020950:Protein male abnormal 21-like 1/2" CG4746 11-Aug-17 DroID_v2017_08 "Drer\itprip, Drer\si:dkey-11f12.2, Drer\mab21l1, Drer\itpripl2, Drer\mab21l2, Drer\mab21l3, Drer\mb21d2, Drer\LOC556707" - Cele\mab-21 "Xtro\mab21l2, Xtro\mab21l1, Xtro\mb21d2" "Mmus\Mab21l3, Mmus\Mab21l2, Mmus\Mb21d1, Mmus\Itpripl1, Mmus\Mb21d2, Mmus\2310007B03Rik, Mmus\Mab21l1, Mmus\Itprip, Mmus\Tmem102, Mmus\Itpripl2" "Hsap\MAB21L1, Hsap\MAB21L3, Hsap\MB21D1, Hsap\C2orf54, Hsap\TMEM102, Hsap\ITPRIPL2, Hsap\ITPRIP, Hsap\MB21D2, Hsap\MAB21L2, Hsap\ITPRIPL1" "viable,fertile" FBgn0041205 key kenny http://flybase.org/reports/FBgn0041205 protein_coding_gene K63-linked polyubiquitin binding ; GO:0070530 | inferred from biological aspect of ancestor with PANTHER:PTN001268347 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VEZ5 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype protein catabolic process ; GO:0030163 | inferred from direct assay negative regulation of stem cell proliferation ; GO:2000647 | inferred from mutant phenotype positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | non-traceable author statement peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of I-kappaB kinase/NF-kappaB signaling ; GO:0043122 | inferred from biological aspect of ancestor with PANTHER:PTN001268347 immune response ; GO:0006955 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "key, dIKK-gamma, IKKgamma, Kenny, IKK-gamma, DmIKKgamma, dIKK, dmIKKgamma, CG16910, Dmikkgamma, DmIKK-gamma, IKKg, Key, kenny, KEY, IKK, IKK[[gamma]], IKKG" "IPR034735:Zinc finger CCHC NOA-type, IPR032419:NF-kappa-B essential modulator NEMO, CC2-LZ domain" CG16910 11-Aug-17 DroID_v2017_08 "Drer\ikbkg, Drer\optn" - - Xtro\optn "Mmus\Cep55, Mmus\Ikbkg, Mmus\Optn" "Hsap\CEP55, Hsap\OPTN, Hsap\IKBKG" "viable,fertile,immune response defective,recessive,oxidative stress response defective" intestinal stem cell FBgn0025161 l(2)GA1019 lethal (2) GA1019 http://flybase.org/reports/FBgn0025161 - gene - - - "GA1019, l(2)GA1019" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cytokinesis defective" ganglion mother cell GMC4-2a FBgn0002868 MtnA Metallothionein A http://flybase.org/reports/FBgn0002868 "FBgn0045904, FBgn0045909, FBgn0045911, FBgn0064964" protein_coding_gene metal ion binding ; GO:0046872 | inferred from direct assay metal ion homeostasis ; GO:0055065 | inferred from mutant phenotype response to metal ion ; GO:0010038 | inferred from sequence or structural similarity with MtnE response to metal ion ; GO:0010038 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "MTN, Mtn, DrosMtn, CG9470, BcDNA:GH18460, anon-WO0153538.49, anon-WO0153538.44, anon-WO0153538.42, MtnA, mtnA" "IPR000966:Metallothionein, family 5, Diptera" CG9470 11-Aug-17 DroID_v2017_08 - "Scer\CUP1-1, Scer\CUP1-2" - - - - "chemical sensitive,viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum,trichogen cell" FBgn0039747 AdoR Adenosine receptor http://flybase.org/reports/FBgn0039747 protein_coding_gene G-protein coupled adenosine receptor activity ; GO:0001609 | inferred from sequence or structural similarity G-protein coupled adenosine receptor activity ; GO:0001609 | inferred from direct assay positive regulation of cAMP biosynthetic process ; GO:0030819 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity regulation of calcium ion import ; GO:0090279 | NOT inferred from direct assay negative regulation of calcium ion import ; GO:0090281 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype adenosine receptor signaling pathway ; GO:0001973 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of carbohydrate metabolic process ; GO:0006109 | inferred from genetic interaction with Adgf-A associative learning ; GO:0008306 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "CG9753, adoR, anon-WO0170980.110, anon-WO0170980.109, AdoR, dADOR, dAdoR, DmAdoR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG9753 11-Aug-17 DroID_v2017_08 "Drer\adora2ab, Drer\adora1b, Drer\or102-3, Drer\or102-1, Drer\si:ch211-233f11.5, Drer\or102-5, Drer\LOC571410, Drer\adora2b, Drer\or106-1, Drer\or102-4, Drer\LOC100330487, Drer\adora2aa, Drer\or107-1, Drer\or106-10, Drer\LOC100007535" - "Cele\C30B5.7, Cele\ador-1, Cele\srsx-9" "Xtro\adora3, Xtro\adora2b, Xtro\adora1, Xtro\adora2a" "Mmus\Gpbar1, Mmus\Adora1, Mmus\Adora2b, Mmus\Tmigd3, Mmus\Adora3, Mmus\Adora2a" "Hsap\ADORA1, Hsap\GPBAR1, Hsap\ADORA2A, Hsap\ADORA2B, Hsap\ADORA3" "visible,melanotic mass phenotype,lethal,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,viable,learning defective,recessive,neurophysiology defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,melanotic mass,scutellum,scutellar bristle,adult external abdomen,embryonic/larval neuromuscular junction,motor neuron,synapse,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0021796 Tor Target of rapamycin http://flybase.org/reports/FBgn0021796 FBgn0032466 protein_coding_gene macromolecular complex binding ; GO:0044877 | inferred from electronic annotation with InterPro:IPR009076 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence model protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:3942 protein kinase activity ; GO:0004672 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7K0T0 inferred from physical interaction with UniProtKB:Q9U9A9 protein self-association ; GO:0043621 | inferred from direct assay "larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from genetic interaction with Rheb regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype positive regulation of protein phosphorylation ; GO:0001934 | inferred from genetic interaction with gig multicellular organism growth ; GO:0035264 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:3942 axon guidance ; GO:0007411 | inferred from genetic interaction with Rheb detection of nutrient ; GO:0009594 | traceable author statement response to nutrient ; GO:0007584 | traceable author statement regulation of response to drug ; GO:2001023 | inferred from mutant phenotype growth ; GO:0040007 | traceable author statement negative regulation of macroautophagy ; GO:0016242 | inferred from mutant phenotype positive regulation of ribosome biogenesis ; GO:0090070 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | traceable author statement positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement phosphorylation ; GO:0016310 | non-traceable author statement determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype regulation of cell growth ; GO:0001558 | inferred from direct assay positive regulation of cell growth ; GO:0030307 | traceable author statement regulation of reactive oxygen species metabolic process ; GO:2000377 | inferred from genetic interaction with InR germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from genetic interaction with Rheb endocytic recycling ; GO:0032456 | inferred from direct assay apical protein localization ; GO:0045176 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype inferred from genetic interaction with gig dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of organ growth ; GO:0046622 | traceable author statement positive regulation of cell growth ; GO:0030307 | non-traceable author statement cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype" TORC1 complex ; GO:0031931 | inferred from sequence or structural similarity with HGNC:3942 TORC2 complex ; GO:0031932 | inferred from sequence or structural similarity with HGNC:3942 "Tor, TOR, dTOR, mTOR, CG5092, dTor, dtor, FRAP/TOR, CT24817, CT24745, CT16317, l(2)k17004, tor, 5092, DmTOR, Tor|TOR, TORC1, Torc1, mTor" "IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR003151:PIK-related kinase, FAT, IPR003152:FATC domain, IPR009076:FKBP12-rapamycin binding domain, IPR011009:Protein kinase-like domain, IPR011989:Armadillo-like helical, IPR013026:Tetratricopeptide repeat-containing domain, IPR014009:PIK-related kinase, IPR016024:Armadillo-type fold, IPR019734:Tetratricopeptide repeat, IPR024585:Domain of unknown function DUF3385, target of rapamycin protein, IPR011990:Tetratricopeptide-like helical domain, IPR026683:Serine/threonine-protein kinase TOR" CG5092 11-Aug-17 DroID_v2017_08 "Drer\prkdc, Drer\smg1, Drer\mtor" "Scer\TOR1, Scer\TOR2" "Cele\let-363, Cele\trr-1" "Xtro\mtor, Xtro\prkdc" "Mmus\Smg1, Mmus\Mtor, Mmus\Prkdc" "Hsap\BOLA2, Hsap\BOLA2B, Hsap\MTOR, Hsap\BOLA2-SMG1P6, Hsap\SMG1, Hsap\PRKDC" "neuroanatomy defective,somatic clone,small body,lethal,recessive,body size defective,decreased cell size,gravitaxis defective,wild-type,mitotic cell cycle defective,developmental rate defective,cell size defective,decreased cell number,lethal - all die before end of larval stage,some die during larval stage,sterile,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,chemical sensitive,dominant,lethal - all die before end of second instar larval stage,some die during second instar larval stage,long lived,visible,size defective,increased cell size,some die during third instar larval stage" "axon | somatic clone,dendrite | somatic clone,anterior fascicle & synapse,intersegmental nerve,larva,larval salivary gland & nucleus,fat body,vesicle,nucleus,intestinal stem cell,chemical conditional,salivary gland imaginal ring,cell cycle,dorsal mesothoracic disc & nucleolus,embryonic/larval fat body,somatic clone,dendritic arborizing neuron,eye disc,embryonic/larval salivary gland,ovary,testis,head,segment border muscle,embryonic/larval somatic muscle,embryonic myoblast,embryonic/larval neuroblast,hemocyte | larval stage,wing,posterior,lysosomeLsp2.PH,autophagic vacuoleLsp2.PH,autophagic vacuoleGMR.PU,eye,mitotic cell cycle | somatic clone,eye-antennal disc primordium" DRSC02811 I -2.259015858 2.217170773 0.006915707 0.300893799 -0.136363955 0.08512951 FBgn0003447 sn singed http://flybase.org/reports/FBgn0003447 FBgn0040925 protein_coding_gene "protein binding, bridging ; GO:0030674 | inferred from electronic annotation with InterPro:IPR022768, InterPro:IPR024703 actin filament binding ; GO:0051015 | inferred from sequence or structural similarity with UniProtKB:Q16658 actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000058080 actin binding ; GO:0003779 | inferred from sequence or structural similarity with UniProtKB:Q16658 actin binding ; GO:0003779 | inferred from sequence or structural similarity" microvillar actin bundle assembly ; GO:0030034 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype epidermal cell differentiation ; GO:0009913 | inferred from mutant phenotype filopodium assembly ; GO:0046847 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype dendrite development ; GO:0016358 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from mutant phenotype actin filament organization ; GO:0007015 | traceable author statement chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype neuron projection ; GO:0043005 | inferred from direct assay nuclear periphery ; GO:0034399 | colocalizes_with inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay actin cytoskeleton ; GO:0015629 | inferred from direct assay "Sn, CG1536, fs(1)M45, fs(1)K418, fs(1)K743, fs(1)K473, fs(1)K1421, fs(1)A1057, CG15331, CG32858, sn, SN" "IPR008999:Actin cross-linking, IPR010431:Fascin, IPR024703:Fascin, metazoans, IPR022768:Fascin domain" CG32858 11-Aug-17 DroID_v2017_08 "Drer\fscn1a, Drer\fscn1b, Drer\fscn2a, Drer\fscn2b" - "Cele\F09C6.1, Cele\frg-1" "Xtro\fscn1, Xtro\fscn2" "Mmus\Fscn1, Mmus\Fscn3, Mmus\Fscn2" "Hsap\FSCN2, Hsap\FSCN1, Hsap\FSCN3" " pupal stage , embryonic stage | early , adult stage && oogenesis stage | mid-late , adult stage , oogenesis stage | mid-late " ovary

" pupal stage , oogenesis stage | stage S9 && adult stage | female , oogenesis stage | stage S10 && adult stage | female " " tormogen cell

, border follicle cell

, macrochaeta

, oocyte

, socket

" "female sterile,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,viable,fertile,visible,partially,sterile,neuroanatomy defective,female fertile,reduced,male fertile,cell polarity defective,cell migration defective,female" "macrochaeta,microchaeta,dorsal appendage,egg,maternal effect,orbital bristle,chaeta,lateral multidendritic neuron ldaB,dorsal multidendritic neuron ddaC,denticle belt,actin filament & egg chamber,macrochaeta & actin filament,nurse cell ring canal,plasmatocyte,neuron,actin filament & neuron,nurse cell,egg chamber,oocyte,nurse cell & nucleus,macrophage,arista,microchaeta & actin filament,denticle,wing hair" FBgn0000535 eag ether a go-go http://flybase.org/reports/FBgn0000535 - protein_coding_gene phosphorelay sensor kinase activity ; GO:0000155 | inferred from electronic annotation with InterPro:IPR000700 voltage-gated cation channel activity ; GO:0022843 | inferred from direct assay voltage-gated potassium channel activity ; GO:0005249 | inferred from direct assay voltage-gated potassium channel activity ; GO:0005249 | traceable author statement transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 phosphorelay signal transduction system ; GO:0000160 | inferred from electronic annotation with InterPro:IPR000700 sensory perception of smell ; GO:0007608 | non-traceable author statement behavioral response to ether ; GO:0048150 | non-traceable author statement courtship behavior ; GO:0007619 | non-traceable author statement flight behavior ; GO:0007629 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | traceable author statement learning or memory ; GO:0007611 | non-traceable author statement regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 perineurial glial growth ; GO:0042066 | inferred from genetic interaction with poe protein oligomerization ; GO:0051259 | inferred from physical interaction with Hk regulation of heart contraction ; GO:0008016 | non-traceable author statement potassium ion transport ; GO:0006813 | inferred from direct assay learning ; GO:0007612 | inferred from mutant phenotype courtship behavior ; GO:0007619 | traceable author statement voltage-gated potassium channel complex ; GO:0008076 | inferred from physical interaction with Hk voltage-gated potassium channel complex ; GO:0008076 | traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay "Eag, CIKE, CG10952, eag, EAG" "IPR018490:Cyclic nucleotide-binding-like, IPR000014:PAS domain, IPR000595:Cyclic nucleotide-binding domain, IPR000700:PAS-associated, C-terminal, IPR003938:Potassium channel, voltage-dependent, EAG/ELK/ERG, IPR003949:Potassium channel, voltage-dependent, EAG, IPR005821:Ion transport domain, IPR001610:PAC motif, IPR014710:RmlC-like jelly roll fold" CG10952 11-Aug-17 DroID_v2017_08 "Drer\kcnh5b, Drer\hcn4l, Drer\kcnh4b, Drer\kcnh1b, Drer\kcnh8, Drer\kcnh3, Drer\kcnh1a, Drer\kcnh4a, Drer\kcnh5a" - Cele\egl-2 "Xtro\kcnh1, Xtro\kcnh5, Xtro\kcnh8" "Mmus\Kcnh8, Mmus\Kcnh5, Mmus\Kcnh3, Mmus\Kcnh4, Mmus\Kcnh1" "Hsap\KCNH1, Hsap\KCNH5, Hsap\KCNH8, Hsap\KCNH4, Hsap\KCNH3" adult stage adult head

"neurophysiology defective,behavior defective,learning defective,smell perception defective,memory defective,taste perception defective,chemical sensitive,recessive,hyperactive,heat sensitive,viable,courtship behavior defective,song defective" "adult brain,neuromuscular junction,synapse,leg" FBgn0053276 Urm1 Ubiquitin-related modifier 1 http://flybase.org/reports/FBgn0053276 protein_coding_gene - tRNA thio-modification ; GO:0034227 | inferred from electronic annotation with InterPro:IPR015221 negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG33276, anon-AE003558.1, Urm1" "IPR015221:Ubiquitin-related modifier 1, IPR016155:Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp, IPR012675:Beta-grasp domain" CG33276 11-Aug-17 DroID_v2017_08 Drer\urm1 Scer\URM1 Cele\urm-1 Xtro\urm1 Mmus\Urm1 Hsap\URM1 viable FBgn0010329 Tbh Tyramine beta hydroxylase http://flybase.org/reports/FBgn0010329 FBgn0012186 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen ; GO:0016715 | inferred from mutant phenotype dopamine beta-monooxygenase activity ; GO:0004500 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN001605435" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000323, InterPro:IPR000945, InterPro:IPR014784, InterPro:IPR020611 dopamine catabolic process ; GO:0042420 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 ovulation ; GO:0030728 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | traceable author statement aggressive behavior ; GO:0002118 | inferred from mutant phenotype octopamine signaling pathway ; GO:0071927 | inferred from direct assay octopamine biosynthetic process ; GO:0006589 | traceable author statement mating behavior, sex discrimination ; GO:0048047 | inferred from genetic interaction with fru regulation of forward locomotion ; GO:0043059 | inferred from direct assay regulation of behavior ; GO:0050795 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype norepinephrine biosynthetic process ; GO:0042421 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 learning ; GO:0007612 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype" secretory granule membrane ; GO:0030667 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000806665 "TBH, Tbetah, T beta h, CG1543, TbetaH, DBH, TBetaH, Dbh, Tbh, tbh, tbetah, TBetah, TbetaM, TBh, TbH" "IPR000323:Copper type II, ascorbate-dependent monooxygenase, N-terminal, IPR000945:Dopamine beta-hydroxylase-related, IPR005018:DOMON domain, IPR008977:PHM/PNGase F domain, IPR014784:Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, IPR024548:Copper type II ascorbate-dependent monooxygenase, C-terminal, IPR028460:Tyramine beta-hydroxylase/Dopamine beta-hydroxylase, IPR015943:WD40/YVTN repeat-like-containing domain, IPR020611:Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site" CG1543 11-Aug-17 DroID_v2017_08 "Drer\moxd1l, Drer\moxd1, Drer\dbh" - Cele\tbh-1 "Xtro\dbh, Xtro\moxd1" "Mmus\Dbh, Mmus\Moxd1, Mmus\Moxd2" "Hsap\DBH, Hsap\MOXD1" adult stage | female " ovary | restricted & vicinity of

, ventral nervous system | restricted & ventral & medial

, oviduct | vicinity of

" "viable,male fertile,female sterile,behavior defective,heat sensitive,fertile,memory defective,locomotor behavior defective,locomotor rhythm defective,neurophysiology defective,male,recessive,mating behavior defective,female limited,courtship behavior defective,neuroanatomy defective,female,flight defective,learning defective,conditional,starvation stress response defective,chemosensitive behavior defective" "larva,gustatory receptor neuron,multidendritic neuron,type I bouton,type II bouton,embryonic/larval neuromuscular junction" FBgn0001987 Gli Gliotactin http://flybase.org/reports/FBgn0001987 - protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 carboxylic ester hydrolase activity ; GO:0052689 | inferred from sequence or structural similarity neurexin family protein binding ; GO:0042043 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 "modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 spermatid differentiation ; GO:0048515 | inferred from mutant phenotype neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype maintenance of imaginal disc-derived wing hair orientation ; GO:0035321 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype establishment of blood-nerve barrier ; GO:0008065 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype" synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 septate junction ; GO:0005918 | inferred from direct assay tricellular tight junction ; GO:0061689 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 "Gli, gli, CG3903, n(2)k09033, BG:DS09217.3, l(2)35Dg, l(2)br45" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR029058:Alpha/Beta hydrolase fold" CG3903 11-Aug-17 DroID_v2017_08 "Drer\nlgn3b, Drer\nlgn1, Drer\nlgn2b, Drer\ces2, Drer\si:ch211-93f2.1, Drer\nlgn4a, Drer\tg, Drer\cell, Drer\nlgn4b, Drer\nlgn2a, Drer\nlgn3a, Drer\cel.1, Drer\ces3" - "Cele\R173.3, Cele\glit-1, Cele\ZK994.1, Cele\ZC376.3, Cele\T02B5.3, Cele\T28C12.5, Cele\Y71H2AM.13, Cele\ZC376.1, Cele\T07H6.1, Cele\Y75B8A.3, Cele\ZC376.2, Cele\nlg-1, Cele\T02B5.1, Cele\K07C11.4, Cele\W02B12.4" "Xtro\nlgn2, Xtro\nlgn4x, Xtro\LOC100494782, Xtro\tg, Xtro\cel, Xtro\ces2, Xtro\nlgn3, Xtro\ces3" "Mmus\Ces5a, Mmus\Nlgn1, Mmus\Ces1g, Mmus\Ces2h, Mmus\Ces2g, Mmus\Cel, Mmus\Ces2c, Mmus\Ces1e, Mmus\Ces2e, Mmus\Ces2f, Mmus\Ces1f, Mmus\Ces1c, Mmus\Ces4a, Mmus\Ces3b, Mmus\Ces1h, Mmus\Ces2b, Mmus\Tg, Mmus\Ces1d, Mmus\Ces3a, Mmus\Nlgn2, Mmus\Nlgn3, Mmus\Ces2a, Mmus\Ces1b" "Hsap\CES4A, Hsap\NLGN4X, Hsap\CEL, Hsap\CES3, Hsap\CES2, Hsap\CES5A, Hsap\NLGN3, Hsap\NLGN1, Hsap\NLGN2, Hsap\TG, Hsap\CES1, Hsap\NLGN4Y" " embryonic stage , embryonic stage | stage 12 " " exit glial cell

, peripheral glial cell

, epidermis

, midline glial cell

" " embryonic stage , larval stage , embryonic stage | stage >=13 , embryonic stage | stage 12 , embryonic stage | stage 13-14 " " segmental nerve

, peripheral nervous system

, peripheral glial cell

, ventral thoracic disc

, epidermis

, eye-antennal disc

, thoracico-abdominal ganglion | medial

, exit glial cell

, embryonic/larval trachea

, midline glial cell

, embryonic/larval hindgut

, intersegmental nerve

" "lethal,increased cell number,increased cell death,viable,fertile,visible,neuroanatomy defective,meiotic cell cycle defective,dominant,recessive,cell polarity defective,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,cell lethalcell lethal,somatic clone" "border follicle cell,somatic clone,wing disc,embryonic/larval salivary gland,macrochaeta,tormogen cell,scutellar bristle,dorsocentral bristle,intersegmental nerve,anterior fascicle & synapse,dorsal trunk primordium,embryonic salivary gland & epithelial cell,septate junction,wing hair,embryonic peripheral glial cell 4,intermediate peripheral glial cell of ISN,embryonic peripheral glial cell 10,peripheral glial cell 4 of SNc,wing,distal,pleated septate junction,epithelial cell,embryonic/first instar larval cuticle,trichogen cell" FBgn0003575 su(sable) suppressor of sable http://flybase.org/reports/FBgn0003575 - protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 RNA binding ; GO:0003723 | inferred from direct assay "nuclear RNA surveillance ; GO:0071027 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay inferred from mutant phenotype" polytene chromosome ; GO:0005700 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | colocalizes_with inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "EG:115C2.3, CG6222, su-s, su-v, su(s), su[2]-s, su(sable)" "IPR000571:Zinc finger, CCCH-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG6222 11-Aug-17 DroID_v2017_08 "Drer\cpsf4, Drer\zc3h4" Scer\YTH1 Cele\T26A8.4 "Xtro\zc3h6, Xtro\cpsf4l, Xtro\cpsf4" "Mmus\Zc3h6, Mmus\Cpsf4l, Mmus\Zc3h8, Mmus\Zc3h4, Mmus\Cpsf4" "Hsap\CPSF4L, Hsap\ZC3H6, Hsap\ZC3H8, Hsap\CPSF4, Hsap\ZC3H4" " adult stage , embryonic stage -- adult stage , embryonic stage " " larval stage | third instar , embryonic stage " salivary gland

"viable,good,wild-type,reduced,male sterile,recessive,cold sensitive,partially lethal - majority live,lethal,male fertile,partially,partially lethal - majority die,visible,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0001234 Hsromega Heat shock RNA omega http://flybase.org/reports/FBgn0001234 FBgn0051400 non_protein_coding_gene - "oogenesis ; GO:0048477 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from genetic interaction with rpr inferred from genetic interaction with grim inferred from genetic interaction with Dcp-1 inferred from genetic interaction with Dronc inferred from genetic interaction with Diap1 positive regulation of JNK cascade ; GO:0046330 | inferred from genetic interaction with egr inferred from genetic interaction with Tak1 inferred from genetic interaction with egr, puc regulation of proteolysis ; GO:0030162 | inferred from mutant phenotype positive regulation of cellular protein metabolic process ; GO:0032270 | inferred from mutant phenotype nuclear speck organization ; GO:0035063 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype inferred from physical interaction with sqd" chromatin ; GO:0000785 | inferred from direct assay omega speckle ; GO:0035062 | inferred from direct assay "hsr-omega, hsromega, Hsr93D, n(3)05241, l(3)05241, hsr omega, hsrw, er3, CR31400, l(3)er3, l(3)93De, Hsromega, HSRomega, Hsr-omega, hrsomega, Hsromega-n" - CR31400 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | third instar , embryonic stage -- adult stage , adult stage | male , embryonic stage | stage >=5 , oogenesis stage , larval stage--adult stage , spermatogenesis " " embryonic/larval proventriculus

, prothoracic gland

, gastric caecum

, embryonic/larval midgut | restricted

, larval optic lobe

, embryonic/larval salivary gland

, embryonic/larval hindgut

, Malpighian tubule

, male reproductive system | restricted

, organism

, nurse cell

, ventral nerve cord

, imaginal disc

, testis | restricted

" "partially lethal - majority die,fertile,heat stress response defective,recessive,viable,male fertile,female fertile,visible,semi-fertile" "rhabdomere,ommatidium,ommatidial precursor cluster" FBgn0000167 bch branch http://flybase.org/reports/FBgn0000167 - gene molecular_function ; GO:0003674 | no biological data available chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bch - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" denticle belt FBgn0038593 Vps39 Vacuolar protein sorting 39 http://flybase.org/reports/FBgn0038593 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR000547 regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with l(2)gd1 autophagosome maturation ; GO:0097352 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with SGD:S000002235 regulation of SNARE complex assembly ; GO:0035542 | inferred from sequence or structural similarity with SGD:S000002235 vesicle-mediated transport ; GO:0016192 | inferred from biological aspect of ancestor with PANTHER:PTN000307050 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype HOPS complex ; GO:0030897 | inferred from sequence or structural similarity with SGD:S000002235 lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN000984757 "CG7146, dVps39, Vps39, vps39, VPS39" "IPR017986:WD40-repeat-containing domain, IPR001180:Citron homology (CNH) domain, IPR019452:Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1, IPR019453:Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2, IPR000547:Clathrin, heavy chain/VPS, 7-fold repeat, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032914:VAM6/VPS39 family" CG7146 11-Aug-17 DroID_v2017_08 "Drer\vps39, Drer\tgfbrap1, Drer\si:ch211-266g18.9" "Scer\VPS3, Scer\VAM6" Cele\vps-39 "Xtro\tgfbrap1, Xtro\vps39" "Mmus\Vps39, Mmus\Tgfbrap1" "Hsap\VPS39, Hsap\TGFBRAP1" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum,embryonic/larval fat body,somatic clone,nutrition conditional,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0015544 spag spaghetti http://flybase.org/reports/FBgn0015544 "FBgn0021904, FBgn0034984" protein_coding_gene Hsp70 protein binding ; GO:0030544 | inferred from sequence or structural similarity with SGD:S000005553 Hsp90 protein binding ; GO:0051879 | inferred from sequence or structural similarity with SGD:S000005553 negative regulation of motor neuron apoptotic process ; GO:2000672 | inferred from mutant phenotype regulation of locomotor rhythm ; GO:1904059 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005553 "l(2)k12101, CG13570, spag, Spag" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR025986:RNA-polymerase II-associated protein 3-like, C-terminal domain" CG13570 11-Aug-17 DroID_v2017_08 Drer\rpap3 Scer\STI1 - Xtro\rpap3 Mmus\Rpap3 Hsap\RPAP3 "lethal,recessive,melanotic mass phenotype,visible,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,neuroanatomy defective,wild-type,lethal - all die during pupal stage" "imaginal disc,embryonic/larval lymph gland,melanotic mass & hemocoel,wing,trichome,secondary lobe of embryonic/larval lymph gland,tertiary lobe of embryonic/larval lymph gland,melanotic mass,synapse" FBgn0039559 NSD Nuclear receptor binding SET domain protein http://flybase.org/reports/FBgn0039559 protein_coding_gene "histone-lysine N-methyltransferase activity ; GO:0018024 | inferred from electronic annotation with InterPro:IPR006560 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965 chromatin DNA binding ; GO:0031490 | inferred from direct assay histone methyltransferase activity ; GO:0042054 | inferred from sequence or structural similarity with WB:WBGene00003222" histone H3-K36 methylation ; GO:0010452 | inferred from sequence or structural similarity with WB:WBGene00003222 germ-line sex determination ; GO:0018992 | inferred from sequence or structural similarity with UniProtKB:Q9NH52 gene silencing ; GO:0016458 | inferred from sequence or structural similarity with UniProtKB:Q9NH52 polytene chromosome ; GO:0005700 | inferred from direct assay pericentric heterochromatin ; GO:0005721 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from sequence or structural similarity with UniProtKB:Q9NH52 "dMES-4, CG4976, dMes-4, MES-4, NSD, Mes-4" "IPR000313:PWWP domain, IPR001214:SET domain, IPR001965:Zinc finger, PHD-type, IPR003616:Post-SET domain, IPR006560:AWS domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4976 11-Aug-17 DroID_v2017_08 "Drer\setd1ba, Drer\phf3, Drer\kmt2d, Drer\nsd1b, Drer\phf20b, Drer\whsc1l1, Drer\phf20l1, Drer\whsc1, Drer\ash1l, Drer\kmt2e, Drer\nsd1a" "Scer\SET4, Scer\BYE1, Scer\SET2, Scer\SET3, Scer\CTI6, Scer\SET1" "Cele\set-9, Cele\C16A11.4, Cele\set-12, Cele\set-26, Cele\set-16, Cele\mes-4, Cele\set-8, Cele\set-5, Cele\met-1, Cele\lin-59, Cele\F19B6.3" "Xtro\setd1b, Xtro\whsc1, Xtro\nsd1" "Mmus\Whsc1l1, Mmus\Kmt2c, Mmus\Spocd1, Mmus\Setd1b, Mmus\Setd2, Mmus\Dido1, Mmus\Phf20l1, Mmus\Kmt2e, Mmus\Whsc1, Mmus\Ash1l, Mmus\Phf3, Mmus\Setd5, Mmus\Nsd1, Mmus\Setbp1, Mmus\Setd1a, Mmus\Kmt2d" "Hsap\KMT2C, Hsap\NSD1, Hsap\SETD1B, Hsap\ASH1L, Hsap\PHF20, Hsap\KMT2E, Hsap\DIDO1, Hsap\KMT2D, Hsap\PHF20L1, Hsap\SETD1A, Hsap\SETD5, Hsap\SETD2, Hsap\WHSC1L1, Hsap\SETBP1, Hsap\WHSC1" viable FBgn0030159 CG9689 - http://flybase.org/reports/FBgn0030159 protein_coding_gene - - - "BcDNA:GH05731, CG9689, lincRNA.S9020" - CG9689 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0259628 B1368 - http://flybase.org/reports/FBgn0259628 gene - - - B1368 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "submarginal cell,wing vein,posterior cell,wing,tarsal segment" FBgn0069162 mcl(3)Z1898 mcl(3)Z1898 http://flybase.org/reports/FBgn0069162 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1898 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0040765 luna luna http://flybase.org/reports/FBgn0040765 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype preblastoderm mitotic cell cycle ; GO:0035185 | inferred from mutant phenotype - "CG17326, DKLF, CG9087, CG33473, Klf, luna, KLF, lincRNA.284, LUNA" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG33473 11-Aug-17 DroID_v2017_08 "Drer\klf12a, Drer\klf17, Drer\klf5b, Drer\klf6a, Drer\klf8, Drer\klf11a, Drer\klf2a, Drer\klf5l, Drer\klf12b, Drer\klf4, Drer\klf6b, Drer\klf13, Drer\klf7b, Drer\klf9, Drer\klf1, Drer\klf11b, Drer\klf7a, Drer\klf5a, Drer\zgc:153115, Drer\klf2b" "Scer\AZF1, Scer\FZF1, Scer\RPN4" "Cele\klf-3, Cele\klu-1, Cele\klf-1, Cele\klf-2" "Xtro\klf17, Xtro\klf2, Xtro\klf9, Xtro\klf12, Xtro\klf8, Xtro\klf5, Xtro\klf10, Xtro\klf3, Xtro\klf13, Xtro\klf11, Xtro\klf4, Xtro\znf534, Xtro\klf7" "Mmus\Klf1, Mmus\Klf7, Mmus\Klf11, Mmus\Klf3, Mmus\Klf6, Mmus\Klf8, Mmus\Klf4, Mmus\Klf5, Mmus\Klf16, Mmus\Klf13, Mmus\Klf9, Mmus\Klf14, Mmus\Klf12, Mmus\Klf2, Mmus\Klf10" "Hsap\KLF10, Hsap\KLF8, Hsap\KLF5, Hsap\KLF4, Hsap\KLF12, Hsap\KLF13, Hsap\KLF9, Hsap\KLF6, Hsap\KLF1, Hsap\KLF3, Hsap\KLF7, Hsap\KLF2, Hsap\KLF14" larval stage | third instar eye-antennal disc

"lethal - all die during embryonic stage,germline clone,mitotic cell cycle defective,maternal effect,oxidative stress response defective,visible,lethal,melanotic necrosis" "eye,ommatidium,interommatidial bristle,supernumerary,pigment cell,eye photoreceptor cell,photoreceptor cell" FBgn0038156 CG14372 - http://flybase.org/reports/FBgn0038156 protein_coding_gene - - - "BP1073, CT34011, CG14372, 14372" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold" CG14372 11-Aug-17 DroID_v2017_08 "Drer\cd22, Drer\si:ch211-1f22.3, Drer\LOC100333244, Drer\LOC100148735, Drer\zmp:0000001289, Drer\nphs1, Drer\mag, Drer\LOC100333105, Drer\hmcn2, Drer\sc:d0284" - - "Xtro\LOC100145501, Xtro\siglec10, Xtro\nphs1" "Mmus\Fcgr1, Mmus\Siglece, Mmus\Mag, Mmus\Siglecg, Mmus\Fcrla, Mmus\Cd22, Mmus\Nphs1, Mmus\Siglecf" "Hsap\SIGLEC7, Hsap\FCRLA, Hsap\SIGLEC5, Hsap\SIGLEC9, Hsap\SIGLEC10, Hsap\SIGLEC6, Hsap\SIGLEC12, Hsap\PSG1, Hsap\MERTK, Hsap\SIGLEC14, Hsap\PSG2, Hsap\SIGLEC11, Hsap\MAG, Hsap\NPHS1, Hsap\SIGLEC8" "viable,body color defective" mesothoracic tergum FBgn0026597 Axn Axin http://flybase.org/reports/FBgn0026597 FBgn0028152 protein_coding_gene beta-catenin binding ; GO:0008013 | inferred from physical interaction with arm GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 protein kinase binding ; GO:0019901 | inferred from physical interaction with sgg somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from genetic interaction with pan response to starvation ; GO:0042594 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of cell death ; GO:0010941 | inferred from genetic interaction with Rbf Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype imaginal disc pattern formation ; GO:0007447 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype inferred from genetic interaction with Wnt2 plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "dAxin, Daxin, axn, axin, DAxin, d-axin, D-Axin, l(3)S044230, din, 0442/30, CG7926, Axn, Axin, dAXIN, APC, GSK3beta" "IPR001158:DIX domain, IPR024066:RGS, subdomain 1, IPR014936:Axin beta-catenin binding, IPR016137:RGS domain, IPR029071:Ubiquitin-related domain" CG7926 11-Aug-17 DroID_v2017_08 "Drer\axin2, Drer\rgs12a, Drer\rgs3a, Drer\rgs8, Drer\rgs5b, Drer\rgs5a, Drer\rgs6, Drer\si:ch211-117l17.6, Drer\grid2ipb, Drer\rgs1, Drer\si:ch211-196h16.12, Drer\rgs19, Drer\rgs12b, Drer\rgs14a, Drer\rgs9b, Drer\si:ch211-117l17.5, Drer\rgs18, Drer\rgs16, Drer\axin1, Drer\rgs11, Drer\rgs4, Drer\rgs2, Drer\rgs13, Drer\rgs17, Drer\rgs14b, Drer\si:ch211-152p11.4" "Scer\RGS2, Scer\SST2" Cele\pry-1 "Xtro\axin1, Xtro\rgs17, Xtro\cep112, Xtro\xarp, Xtro\rgs5, Xtro\rgs3, Xtro\rgs2, Xtro\rgs4, Xtro\rgs10, Xtro\rgs16, Xtro\rgs20, Xtro\rgs19, Xtro\rgs1, Xtro\rgs6, Xtro\rgs18" "Mmus\Rgs9, Mmus\Rgs5, Mmus\Rgs19, Mmus\Axin1, Mmus\Axin2, Mmus\Rgs12, Mmus\Rgs4, Mmus\Rgs8, Mmus\Rgs3, Mmus\Rgs18, Mmus\Rgs13, Mmus\Rgs17, Mmus\Rgs10, Mmus\Rgs1, Mmus\Rgs6, Mmus\Rgs14, Mmus\Rgs7, Mmus\Rgs11, Mmus\Rgs16, Mmus\Rgs20, Mmus\Rgs2" "Hsap\RGS12, Hsap\RGS21, Hsap\RGS1, Hsap\RGS11, Hsap\RGS10, Hsap\RGS19, Hsap\RGS5, Hsap\RGS17, Hsap\RGS14, Hsap\RGS6, Hsap\RGS9, Hsap\RGS7, Hsap\RGS8, Hsap\RGS3, Hsap\RGS16, Hsap\RGS20, Hsap\AXIN2, Hsap\AXIN1, Hsap\RGS4, Hsap\RGS18, Hsap\RGS13, Hsap\RGS2" embryonic stage -- adult stage embryonic stage "partially lethal - majority live,maternal effect,some die during embryonic stage,lethal,majority die during embryonic stage,lethal - all die before end of P-stage,lethal - all die during embryonic stage,recessive,visible,somatic clone,cell shape defective,lethal - all die before end of embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,viable,wild-type,mitotic cell cycle defective,neuroanatomy defective" "denticle row 1,maternal effect,denticle belt,embryonic/first instar larval cuticle,denticle row,ectopic,wing,somatic clone,wing margin bristle,follicle stem cell,germline cyst,follicle cell,G1 phase | somatic clone,cell autonomous,macrochaeta,leg,adult abdomen,adult abdomen & macrochaeta | somatic clone,intestinal stem cell,germline clone,wing disc,denticle,supernumerary,sternite,wing margin,embryonic/larval cuticle | embryonic stage,eye disc,eye,frons,adult cuticle,mitotic cell cycle | somatic clone,photoreceptor cell,wing & chaeta | ectopic | somatic clone,embryonic epidermis,morphogenetic furrow,ovary,mesothoracic tergum,trichome of the posterior wing margin,embryonic/larval dorsal trunk,embryonic/larval dorsal branch,embryonic/larval lateral trunk,tracheal tip cell,ventral thoracic disc,abdominal sternite bristle,multidendritic neuron,dorsal medial muscle,indirect flight muscle,adult heart,tracheal fusion cell" DRSC14120 IK 2.752572319 -2.201592853 -0.290373448 0.405321213 2.560180287 1.811448276 FBgn0261869 caboose caboose http://flybase.org/reports/FBgn0261869 gene - larval foraging behavior ; GO:0035177 | inferred from mutant phenotype - "caboose, cbs" - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0085005 ey::eyg ey::eyg http://flybase.org/reports/FBgn0085005 engineered_fusion_gene - - - ey::eyg - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye,ectopic,ventral,eye | pharate adult stage,wing disc" FBgn0031059 CG14229 - http://flybase.org/reports/FBgn0031059 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE31307, CG14229" - CG14229 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0020887 Su(z)12 Su(z)12 http://flybase.org/reports/FBgn0020887 "FBgn0025924, FBgn0036917" protein_coding_gene DNA binding ; GO:0003677 | non-traceable author statement histone methyltransferase activity ; GO:0042054 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24459 nucleosome binding ; GO:0031491 | contributes_to inferred from direct assay chromatin DNA binding ; GO:0031490 | inferred from biological aspect of ancestor with PANTHER:PTN000502888 histone methyltransferase activity (H3-K27 specific) ; GO:0046976 | contributes_to inferred by curator from GO:0035098 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000502888 negative regulation of response to gamma radiation ; GO:2001229 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement neuron development ; GO:0048666 | inferred from mutant phenotype gene silencing ; GO:0016458 | non-traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype histone methylation ; GO:0016571 | inferred from direct assay" ESC/E(Z) complex ; GO:0035098 | inferred from direct assay nuclear chromatin ; GO:0000790 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay histone methyltransferase complex ; GO:0035097 | inferred from direct assay RSC complex ; GO:0016586 | inferred from biological aspect of ancestor with PANTHER:PTN000502889 "Su(z)12, l(3)76BDo, CG8013, SU(Z)12, Su(z)[12], Su(Z)12, su(z)12, SUZ12, Suz(12), Suz12" "IPR019135:Polycomb protein, VEFS-Box" CG8013 11-Aug-17 DroID_v2017_08 "Drer\suz12a, Drer\suz12b" "Scer\NPL6, Scer\SWP82, Scer\PRP19" "Cele\F25H8.2, Cele\cope-1" Xtro\suz12 Mmus\Suz12 Hsap\SUZ12 "suppressor of variegation,dominant,decreased cell number,somatic clone,mitotic cell cycle defective,neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,visible,lethal,homeotic,viable" "egg,germline clone,neuroblast,somatic clone,dendrite & dendritic arborising neuron | somatic clone,wing,cell non-autonomous,wing hinge,cell autonomous,embryonic abdominal segment,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic head segment,dendrite & dendritic arborising neuron,dendrite & dendritic arborising neuron125),ovary,dendrite & dorsal multidendritic neuron ddaC | somatic clone,sex comb,ectopic,mesothoracic metatarsus,antenna,leg,haltere,metathoracic metatarsus,dendrite & dendritic arborising neuron122),embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0030994 HP1D3csd Heterochromatin Protein 1D3 chromoshadow domain http://flybase.org/reports/FBgn0030994 protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with Su(var)205 chromosome organization ; GO:0051276 | inferred from sequence or structural similarity with Su(var)205 chromatin ; GO:0000785 | inferred from sequence or structural similarity with Su(var)205 "HP1D3csd, CG14193" "IPR016197:Chromo domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG14193 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0060523 l(3)S102303b lethal (3) S102303b http://flybase.org/reports/FBgn0060523 gene - - - "1023/03, l(3)S102303b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0004921 Ggamma1 G protein gamma 1 http://flybase.org/reports/FBgn0004921 FBgn0022062 protein_coding_gene "signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR001770, InterPro:IPR015898" cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype regulation of gastrulation ; GO:0010470 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype apical protein localization ; GO:0045176 | traceable author statement regulation of myosin II filament organization ; GO:0043519 | inferred from mutant phenotype mesectoderm development ; GO:0048383 | inferred from mutant phenotype establishment or maintenance of cytoskeleton polarity involved in gastrulation ; GO:0003380 | inferred from mutant phenotype proboscis extension reflex ; GO:0007637 | inferred from mutant phenotype heart process ; GO:0003015 | inferred from mutant phenotype convergent extension involved in gastrulation ; GO:0060027 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay heterotrimeric G-protein complex ; GO:0005834 | inferred from direct assay "Gbetagamma, Ggamma, G[[gamma]], l(2)k08017, Ggamma1, Ggamma-1, D-G[[gamma]]1, dg1alpha, CG8261, bro4, Gg1, G[[gamma1]], GNG13, ggamma1" "IPR001770:G-protein, gamma subunit, IPR015898:G-protein gamma-like domain" CG8261 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-117i10.1, Drer\gng2, Drer\gng3, Drer\gngt2a, Drer\gng8, Drer\gng13a, Drer\gng10, Drer\gng5, Drer\si:dkey-204f11.64, Drer\si:dkey-44g17.6, Drer\gngt2b, Drer\gng12a, Drer\gng13b, Drer\gng7, Drer\gngt1" - "Cele\gpc-2, Cele\gpc-1" "Xtro\gng7, Xtro\LOC100489837, Xtro\gngt1, Xtro\gng3, Xtro\gng5, Xtro\gng2, Xtro\gng13" "Mmus\Gng11, Mmus\Gng3, Mmus\Gng5, Mmus\Gngt2, Mmus\Gng2, Mmus\Gngt1, Mmus\Gm5741, Mmus\Gng4, Mmus\Gng10, Mmus\Gng13, Mmus\Gng7, Mmus\Gng12, Mmus\Gng8" "Hsap\GNG8, Hsap\GNG5, Hsap\GNG13, Hsap\GNG12, Hsap\GNG10, Hsap\DNAJC25-GNG10, Hsap\GNG7, Hsap\GNGT2, Hsap\GNG4, Hsap\GNG11, Hsap\GNG3, Hsap\GNGT1, Hsap\GNG2" " oogenesis stage && adult stage | female , adult stage , adult stage && oogenesis stage , adult stage | female , embryonic stage | 18-21 hr , adult stage | male , larval stage | third instar , embryonic stage | 7-12 hr " " ovary

, subesophageal ganglion

, oocyte

, adult thorax

, thorax

, embryonic brain

, head

, imaginal disc

, larval brain

, adult head

, adult abdomen

, embryonic nervous system

, optic lobe

, ventral nerve cord

, nurse cell

, adult brain

,

ubiquitous " "lethal,recessive,cell polarity defective,neurophysiology defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,taste perception defective,neuroanatomy defective,viable,visible" "embryonic pericardial cell,cardioblast,neuroblast,spindle & neuroblast,ganglion mother cell,embryonic neuroblast,embryonic/larval neuroblast,mesothoracic tergum,gastrula embryo,germline clone" FBgn0002774 mle maleless http://flybase.org/reports/FBgn0002774 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 RNA binding ; GO:0003723 | inferred from physical interaction with roX2 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent helicase activity ; GO:0008026 | traceable author statement RNA helicase activity ; GO:0003724 | non-traceable author statement chromatin binding ; GO:0003682 | inferred from direct assay" "dosage compensation ; GO:0007549 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from genetic interaction with cac RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 positive regulation of heterochromatin assembly ; GO:0031453 | inferred from genetic interaction with Su(var)3-7 dosage compensation ; GO:0007549 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype dosage compensation by hyperactivation of X chromosome ; GO:0009047 | non-traceable author statement dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome ; GO:0016457 | traceable author statement determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype dosage compensation ; GO:0007549 | inferred from direct assay" "chromosome ; GO:0005694 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | traceable author statement chromatin ; GO:0000785 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay cytoplasm ; GO:0005737 | colocalizes_with inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay X chromosome ; GO:0000805 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | colocalizes_with inferred from direct assay MSL complex ; GO:0072487 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | non-traceable author statement nucleus ; GO:0005634 | colocalizes_with inferred from direct assay" "MLE, nap[ts], CG11680, nap, mls, mll, mak, mle, Mle" "IPR001650:Helicase, C-terminal, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR014720:Double-stranded RNA-binding domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011545:DEAD/DEAH box helicase domain" CG11680 11-Aug-17 DroID_v2017_08 "Drer\tdrd9, Drer\dhx9, Drer\dhx30, Drer\dhx29, Drer\dhx36, Drer\dhx57" Scer\YLR419W Cele\rha-1 "Xtro\dhx30, Xtro\tdrd9, Xtro\dhx9, Xtro\dhx29, Xtro\dhx36, Xtro\ythdc2" "Mmus\Dhx57, Mmus\Tdrd9, Mmus\Dhx9, Mmus\Dhx29, Mmus\Dhx30, Mmus\Dhx36, Mmus\Ythdc2" "Hsap\TDRD9, Hsap\YTHDC2, Hsap\DHX36, Hsap\DHX30, Hsap\DHX57, Hsap\DHX9, Hsap\DHX29" embryonic stage -- adult stage " adult stage | female , adult stage | male " "viable,fertile,behavior defective,recessive,heat sensitive,lethal - all die before end of larval stage,some die during third instar larval stage,male sterile,lethal,male,some die during larval stage,wild-type,partially,male limited,paralytic,chemical resistant,chemical sensitive,neurophysiology defective,short lived,song defective,neuroanatomy defective,locomotor behavior defective,poor,male fertile,partially lethal - majority live,partially lethal - majority die,some die during pupal stage" "wing,abdomen & macrochaeta,spermatozoon,heat sensitive,chromosome,embryonic/larval heart,neuromuscular junction & synapse | conditional ts,synapse | ectopic | heat sensitive,adult brain,axon & motor neuron | conditional ts,embryonic/larval neuromuscular junction,NMJ bouton,giant fiber neuron,polytene chromosome" FBgn0016736 SR3-6 Suppressor of Ras85D 3-6 http://flybase.org/reports/FBgn0016736 - gene - - - SR3-6 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052095 CG32095 - http://flybase.org/reports/FBgn0052095 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH03217, BcDNA:GH03217, CG32095, DPLG3" IPR027806:Harbinger transposase-derived nuclease domain CG32095 11-Aug-17 DroID_v2017_08 "Drer\LOC569097, Drer\zgc:194221, Drer\zgc:162945, Drer\LOC100005423, Drer\zmp:0000000634, Drer\zgc:113227, Drer\LOC103911715" - - Xtro\LOC100127800 Mmus\Harbi1 Hsap\HARBI1 viable FBgn0030328 Amun Amun http://flybase.org/reports/FBgn0030328 protein_coding_gene - compound eye development ; GO:0048749 | inferred from genetic interaction with Dl wing disc development ; GO:0035220 | inferred from genetic interaction with Dl chaeta development ; GO:0022416 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "EP1503, anon-WO03040301.107, anon-WO03040301.105, anon-WO03040301.104, Amun, CG2446, amun" - CG2446 11-Aug-17 DroID_v2017_08 Drer\zgc:112496 - - Xtro\LOC100145131 - - "visible,body color defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,neuroanatomy defective,lethal,recessive" "eye,macrochaeta & mesothoracic tergum | supernumerary-537.4,macrochaeta & mesothoracic tergum | ectopic-537.4,macrochaeta & mesothoracic tergum-537.4,macrochaeta & mesothoracic tergum | supernumeraryptc-559.1,macrochaeta & mesothoracic tergum | ectopicptc-559.1,macrochaeta & mesothoracic tergumptc-559.1,microchaeta & mesothoracic tergumsr-md710,microchaeta & mesothoracic tergumpnr-MD237,trichogen cell,mesothoracic tergum,neuron & mesothoracic tergum primordium | pupal stagepnr-MD237,trichogen cell & mesothoracic tergum primordium | pupal stagepnr-MD237,sensory mother cell & mesothoracic tergum primordium | pupal stagepnr-MD237,microchaeta & mesothoracic tergum | somatic clone,tormogen cell,scutellar bristle,ectopic" DRSC28058 K 0.003791622 0.983694793 0.37657063 -0.095783708 0.802718505 1.831132343 FBgn0067306 D10 D10 http://flybase.org/reports/FBgn0067306 gene - - - D10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,viable" ommatidium FBgn0038197 foxo "forkhead box, sub-group O" http://flybase.org/reports/FBgn0038197 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype chromatin DNA binding ; GO:0031490 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VS24" "negative regulation of cell proliferation=0008285 |...<> cellular response to amino acid starvation=0034198 |... direct assay <> negative regulation of cell growth=0030308 |...<> regulation of organ growth=0046620 |...<> negative regulation of cell size=0045792 |...<> ecdysone biosynthetic process=0006697 |...<> positive regulation of transcription from RNA polymerase II promoter=0045944 |...<> multicellular organism aging=0010259 |...<> regulation of cell growth=0001558 |...<> circadian rhythm=0007623 |...<> regulation of hemocyte proliferation=0035206 |...<> determination of adult lifespan=0008340 |... genetic interaction with aop inferred from genetic interaction with pnt <> cellular response to oxidative stress=0034599 |...<> cellular response to starvation=0009267 |...<> regulation of macroautophagy=0016241 |...<> positive regulation of transcription from RNA polymerase II promoter=0045944 |... direct assay <> microtubule bundle formation=0001578 |... direct assay <> positive regulation of octopamine signaling pathway=2000130 |...<> positive regulation of transcription, DNA-templated=0045893 |...<> glycogen metabolic process=0005977 |...<> regulation of activin receptor signaling pathway=0032925 |...<> cellular response to DNA damage stimulus=0006974 |...<> regulation of autophagy=0010506 |...<> myoblast fusion=0007520 |...<> negative regulation of multicellular organism growth=0040015 |...<> response to oxidative stress=0006979 |...<> somatic muscle development=0007525 |...<> regulation of growth=0040008 |... genetic interaction with 14-3-3ε <> locomotor rhythm=0045475 |... genetic interaction with InR <> female germ-line stem cell population maintenance=0036099 |...<> negative regulation of insulin receptor signaling pathway=0046627 |...<> determination of adult lifespan=0008340 |...<> regulation of lipid metabolic process=0019216 |...<> dendrite morphogenesis=0048813 |...<> response to bacterium=0009617 |...<> regulation of multicellular organism growth=0040014 |...<> positive regulation of transcription, DNA-templated=0045893 |... direct assay <> negative regulation of lipid storage=0010888 |... direct assay <> positive regulation of cellular response to insulin stimulus=1900078 |... genetic interaction with InR <> regulation of transcription, DNA-templated=0006355 |...<> compound eye morphogenesis=0001745 |...<> glucose homeostasis=0042593 |...<> cAMP biosynthetic process=0006171 |... direct assay inferred from<> response to bacterium=0009617 |... direct assay <> positive regulation of feeding behavior=2000253 |...inferred from genetic interaction with mnb <> regulation of insulin receptor signaling pathway=0046626 |... genetic interaction with Akt1 inferred from genetic interaction with Pi3K92E inferred from genetic interaction with chico inferred from genetic interaction with Tsc1 inferred from genetic interaction with Pten inferred from genetic interaction with InR <> insulin receptor signaling pathway=0008286 |... genetic interaction with Akt1 inferred from physical interaction with Thor inferred from physical interaction with InR <> imaginal disc-derived wing morphogenesis=0007476 |...<> response to starvation=0042594 |...<> negative regulation of transcription, DNA-templated=0045892 |... mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 nucleus ; GO:0005634 | inferred by curator from GO:0001077 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "foxo, CG3143, dFOXO, Dfoxo, dFoxo, Foxo, FOXO, cg3143, Q95V55, DmQ95V5, Afx, FKHR, anon-WO0118547.374, dFoxO, dfoxo, FoxO, 3143, fd88A, foxO, foxo|dFOXO, FOXO1, dfoxO, DFOXO" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain, IPR030456:Fork head domain conserved site 2" CG3143 11-Aug-17 DroID_v2017_08 "Drer\foxo3b, Drer\foxo1a, Drer\foxo4, Drer\foxo1b, Drer\si:ch211-206a7.2, Drer\foxo3a, Drer\si:dkey-11f5.5" "Scer\FKH2, Scer\HCM1, Scer\FKH1, Scer\FHL1" "Cele\let-381, Cele\daf-16" "Xtro\snx24, Xtro\foxo3, Xtro\foxo4, Xtro\foxo1" "Mmus\Foxo1, Mmus\Foxo3, Mmus\Foxo4, Mmus\Foxo6" "Hsap\FOXO4, Hsap\FOXO1, Hsap\FOXO6, Hsap\FOXO3" "decreased cell number,viable,fertile,visible,neuroanatomy defective,stress response defective,aging defective,short lived,nutrition conditional,developmental rate defective,small body,oxidative stress response defective,circadian rhythm defective,immune response defective,increased cell death,long lived,RU486 conditional,locomotor behavior defective,body size defective,mitotic cell cycle defective,chemosensitive behavior defective,female,female fertile,reduced,chemical resistant,wild-type,lethal - all die before end of larval stage,some die during larval stage,feeding behavior defective,lethal,heat sensitive,decreased cell size,somatic clone,starvation stress response defective,male limited,temperature response defective" "germarium cap cell,embryonic/larval neuromuscular junction,type I bouton,microtubule,wing,segment border muscle,A1-7 dorsal acute muscle 1,embryonic/larval somatic muscle,embryonic myoblast,eye,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,muscle cell,supernumerary,synaptic vesicle,ommatidium,mushroom body neuroblast,eye disc,adult heart,neurite | pharate adult stage,retina,adult brain,abdominal adult fat mass,microtubuleRapGAP1-OK6,anterior crossvein,interommatidial bristle,wing cell,embryonic/larval neuroblast,adult gut,heat sensitive,adult anterior midgut epithelium,embryonic/larval fat body,somatic clone,synaptic vesicleRapGAP1-OK6,bouton,dorsal appendage,drug conditional,chorion,microtubuleD42,adult,intestinal stem cell,microtubuleelav.PLu" DRSC13017 K -2.306068294 -0.355575985 FBgn0053523 CG33523 - http://flybase.org/reports/FBgn0053523 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR016763 endomembrane system ; GO:0012505 | inferred from direct assay "CG10977, BcDNA:GH09028, CG10727, CG32410, CG33523, Vap-33B" "IPR000535:Major sperm protein (MSP) domain, IPR001251:CRAL-TRIO lipid binding domain, IPR008962:PapD-like, IPR013783:Immunoglobulin-like fold, IPR016763:Vesicle-associated membrane-protein-associated protein, IPR011074:CRAL/TRIO, N-terminal domain" CG33523 11-Aug-17 DroID_v2017_08 "Drer\rlbp1a, Drer\clvs2, Drer\vapa, Drer\vapal, Drer\sec14l8, Drer\mospd2, Drer\ttpa, Drer\vapb, Drer\ttpal, Drer\sec14l7" "Scer\SCS22, Scer\SEC14, Scer\CSR1, Scer\SCS2, Scer\YKL091C, Scer\SFH5" "Cele\hpo-28, Cele\T03F7.7, Cele\C15H11.1, Cele\ZC196.2" "Xtro\ttpa, Xtro\clvs1, Xtro\mospd3, Xtro\vapa, Xtro\sec14l1, Xtro\ttpal, Xtro\rlbp1, Xtro\sec14l5, Xtro\mospd2, Xtro\sec14l3, Xtro\vapb, Xtro\clvs2" "Mmus\Sec14l2, Mmus\Ttpa, Mmus\Sec14l1, Mmus\Sec14l3, Mmus\Vapa, Mmus\Mospd2, Mmus\Ttpal, Mmus\Clvs1, Mmus\Sec14l5, Mmus\Sec14l4, Mmus\Clvs2, Mmus\Mospd3, Mmus\Rlbp1, Mmus\Vapb" "Hsap\SEC14L1, Hsap\TTPAL, Hsap\RLBP1, Hsap\SEC14L3, Hsap\MOSPD2, Hsap\CLVS1, Hsap\SEC14L5, Hsap\TTPA, Hsap\VAPA, Hsap\VAPB, Hsap\SEC14L4, Hsap\SEC14L2, Hsap\SEC14L6, Hsap\MOSPD3, Hsap\CLVS2" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,anterior fascicle & synapse,intersegmental nerve" FBgn0000382 csw corkscrew http://flybase.org/reports/FBgn0000382 "FBgn0004637, FBgn0026663, FBgn0029599, FBgn0066824, FBgn0066826, FBgn0066827" protein_coding_gene receptor signaling protein tyrosine phosphatase activity ; GO:0004728 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay non-membrane spanning protein tyrosine phosphatase activity ; GO:0004726 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with dos "mesoderm development ; GO:0007498 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | traceable author statement protein dephosphorylation ; GO:0006470 | inferred from direct assay regulation of compound eye photoreceptor development ; GO:0045314 | inferred from mutant phenotype dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | traceable author statement negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype dephosphorylation ; GO:0016311 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype inferred from genetic interaction with Egfr torso signaling pathway ; GO:0008293 | non-traceable author statement terminal region determination ; GO:0007362 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with Egfr epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype R7 cell fate commitment ; GO:0007465 | inferred from genetic interaction with sev sevenless signaling pathway ; GO:0045500 | traceable author statement open tracheal system development ; GO:0007424 | inferred from genetic interaction with bnl anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement ventral midline development ; GO:0007418 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | non-traceable author statement "csw, Csw, EG:BACN25G24.2, CG3954, Csw/Shp2, l(1)2Db, E(sev)1A, CSW, l(1)G0170, l(1)2Dd, l(1)csw, 19-106, l(1)GA114, anon-WO03040301.219, anon-WO03040301.209, anon-WO03040301.207, Shp2/csw, SHP-2, Shp-2, csw/SHP-2" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR000980:SH2 domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR003595:Protein-tyrosine phosphatase, catalytic" CG3954 11-Aug-17 DroID_v2017_08 "Drer\ptpn11b, Drer\ptpn11a, Drer\ptpn6" "Scer\PTP3, Scer\PTP2, Scer\PTP1" "Cele\ZK354.8, Cele\F38H4.4, Cele\K07F5.8, Cele\C17H12.3, Cele\F25H5.7, Cele\F47B3.7, Cele\sdf-9, Cele\ptp-2, Cele\ZK484.7, Cele\C55B7.3, Cele\F36H12.10, Cele\F47B3.1, Cele\Y48G9A.9, Cele\T27A3.5, Cele\eak-6, Cele\C02B10.6, Cele\F55F8.7" "Xtro\MGC107851, Xtro\ptpn6" "Mmus\Ptpn6, Mmus\Ptpn11" "Hsap\PTPN6, Hsap\PTPN11" " embryonic stage | late , larval stage--adult stage , embryonic stage "

ubiquitous "visible,somatic clone,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,wild-type,dominant,increased cell death,germline clone,rescuable maternal effect,maternal effect,viable,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage" "tarsal segment,wing vein L5,ommatidium,interommatidial bristle,eye,somatic clone,eye disc,chromosome & larval neuroblast,metaphase,eye photoreceptor cell,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R7,photoreceptor cell,precursor,outer photoreceptor cell,mesoderm,germline clone,embryonic/first instar larval cuticle,neurogenic region,tracheal precursor cell,embryonic epidermis,posterior,embryo,maternal effect,embryonic head,photoreceptor,egg chamber,chorion | maternal effect | somatic clone,amnioproctodeal invagination,Malpighian tubule primordium,commissure,longitudinal connective,arista,unguis,A1-7 dorsal acute muscle 1,A1-7 ventral acute muscle 2,wing vein,chorion | maternal effect,denticle belt,extended germ band embryo,distal,wing vein L2,wing vein L4,dorsal appendage,embryonic/larval pericardial cell,embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/larval midgut,ectopic,wing,crossvein,trichogen cell,mesothoracic tergum" DRSC18756 IK -1.266121735 -2.893023686 -0.059697079 -0.111770866 -3.561355118 -3.747142596 FBgn0029123 SoxN SoxNeuro http://flybase.org/reports/FBgn0029123 protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with SNCF chromatin DNA binding ; GO:0031490 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" axon guidance ; GO:0007411 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay central nervous system development ; GO:0007417 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "SoxN, soxN, Sox B1, CG18024, SOXB1, SOX29F, DM64, Sry-rDM64" "IPR009071:High mobility group box domain, IPR022097:Transcription factor SOX" CG18024 11-Aug-17 DroID_v2017_08 "Drer\LOC103910042, Drer\sox11b, Drer\sox12, Drer\sox19a, Drer\sox1a, Drer\sox2, Drer\sox4b, Drer\sox4a, Drer\sox3, Drer\sox21a, Drer\sox1b, Drer\sox11a, Drer\sox21b, Drer\sox14, Drer\sox19b" "Scer\ROX1, Scer\IXR1" "Cele\sem-2, Cele\sox-2, Cele\hmg-4, Cele\hmg-3, Cele\sox-3, Cele\eor-2" "Xtro\sox14, Xtro\sox2, Xtro\sox3, Xtro\sox1, Xtro\sox21" "Mmus\Sox11, Mmus\Sox15, Mmus\Sox21, Mmus\Sox2, Mmus\Sox4, Mmus\Sox12, Mmus\Sox3, Mmus\Sry, Mmus\Sox1, Mmus\Sox14" "Hsap\SOX2, Hsap\SOX21, Hsap\SOX15, Hsap\SOX4, Hsap\SRY, Hsap\SOX14, Hsap\SOX11, Hsap\SOX3, Hsap\SOX1, Hsap\SOX12" " embryonic stage | stage 10 , embryonic stage | stage 12 , embryonic stage | stage 8 " " ventral neurogenic region

, ventral nerve cord primordium && embryonic central nervous system | restricted

, ventral nerve cord primordium

" " embryonic stage | stage 10 , embryonic stage | stage 12 , embryonic stage | stage 8 " " ventral nerve cord primordium

, ventral nerve cord primordium | restricted && central nervous system | restricted

, ventral neurogenic region

" "neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during pupal stage,lethal" "denticle,ectopic,cell autonomous,embryonic head,midgut constriction,denticle belt,RP2 motor neuron,EL neuron,aCC neuron,pCC neuron,ganglion mother cell,stage 1 neuroblast,neuroblast NB3-5,neuroblast NB2-5,neuroblast NB5-3,neuroblast NB3-2,neuroblast NB5-6,neuroblast NB7-4,neuroblast NB2-2,neuroblast NB4-2,neuroblast NB6-2,neuroblast NB7-2,neuroblast NB3-1,neuroblast NB4-1,neuroblast NB6-1,neuroblast NB6-4,stage 2 neuroblast,stage 3 neuroblast,stage 4 neuroblast,stage 5 neuroblast,neuroblast NB2-1,neuroblast NB2-4,neuroblast NB3-3,neuroblast NB4-4,neuroblast NB5-4,neuroblast NB5-1,neuroblast NB4-3,neuroblast NB5-5,neuroblast NB7-3,neuroblast NB1-1,neuroblast MP2,neuroblast NB5-2,embryonic/first instar larval cuticle,axon & ventral nerve cord,anterior commissure,posterior commissure,longitudinal connective,commissure,extended germ band embryo,embryonic/larval neuron,EG neuron,embryonic/larval glial cell,neuroblast NB7-1,embryonic neuroblast,U neuron,connective,adult head,axon & ventral nerve cordelav.PLu,wing,thorax,leg,eye,denticle row" FBgn0005198 gig gigas http://flybase.org/reports/FBgn0005198 - protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from direct assay kinase binding ; GO:0019900 | inferred from physical interaction with Tor protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9XYZ5 protein kinase binding ; GO:0019901 | inferred from physical interaction with UniProtKB:Q8T9I6 "regulation of small GTPase mediated signal transduction ; GO:0051056 | inferred from electronic annotation with InterPro:IPR000331 regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from genetic interaction with Tsc1 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype response to nutrient ; GO:0007584 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from biological aspect of ancestor with PANTHER:PTN000006943 negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype inferred from genetic interaction with Tsc1 positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from genetic interaction with Tsc1 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype negative regulation of organ growth ; GO:0046621 | inferred from genetic interaction with Tsc1 regulation of phosphorylation ; GO:0042325 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of cell growth ; GO:0030308 | inferred from genetic interaction with UniProtKB:Q8INB9 negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype TORC1 signaling ; GO:0038202 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from genetic interaction with UniProtKB:Q8T9I6 cholesterol homeostasis ; GO:0042632 | inferred from genetic interaction with Tsc1 negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from genetic interaction with Tor negative regulation of insulin receptor signaling pathway ; GO:0046627 | inferred from genetic interaction with InR oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype lipid metabolic process ; GO:0006629 | inferred from genetic interaction with Tsc1 positive regulation of protein phosphorylation ; GO:0001934 | inferred from direct assay positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype larval midgut histolysis ; GO:0035069 | inferred from genetic interaction with Tsc1, Atg18a inferred from genetic interaction with Tsc1, Atg1 cellular response to chloroquine ; GO:1902350 | inferred from mutant phenotype negative regulation of protein kinase B signaling ; GO:0051898 | inferred from biological aspect of ancestor with PANTHER:PTN000006943" cytoplasm ; GO:0005737 | inferred from direct assay TSC1-TSC2 complex ; GO:0033596 | inferred from physical interaction with Tsc1 "tsc2, gig, TSC2, Tsc2, dTSC2, gigas, dTsc2, C1, l(3)109, ME 109, CG6975, Tsc2/gig, 6975, Gigas, gig|Tsc2, gig/Tsc2, FBpp0074588" "IPR000331:Rap GTPase activating protein domain, IPR003913:Tuberin, IPR011989:Armadillo-like helical, IPR024584:Tuberin, N-terminal, IPR018515:Tuberin-type domain, IPR016024:Armadillo-type fold" CG6975 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-166d12.2, Drer\tsc2, Drer\rap1gap2a" - Cele\F53A10.2 Xtro\tsc2 "Mmus\Rap1gap2, Mmus\Rap1gap, Mmus\Tsc2" "Hsap\RAP1GAP2, Hsap\TSC2, Hsap\RAP1GAP" "size defective,wild-type,visible,recessive,lethal - all die before end of larval stage,some die during larval stage,melanotic mass phenotype,lethal,neuroanatomy defective,smell perception defective,somatic clone,increased cell size,decreased cell number,cell autonomous,cell non-autonomous,grooming behavior defective,large body,decreased cell growth,decreased cell death,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,body color defective,partially lethal - majority die" "oocyte,germline clone,eye,ommatidium,wing,wing margin bristle,photoreceptor cell,cone cell,pigment cell,interommatidial bristle,rhabdomere,antenna,somatic clone,adult antennal nerve,antennal lobe,antennal lobe glomerulus V,microchaeta,macrochaeta,mesothoracic tergum,anterior scutellar bristle & neuron | somatic clone,anterior notopleural bristle & neuron | somatic clone,posterior notopleural bristle & neuron | somatic clone,humeral bristle & neuron | somatic clone,vertical bristle & neuron | somatic clone,embryonic/larval neuromuscular junction,NMJ bouton,cell cycle,eye disc,wing disc,eye disc & S phase | ectopic | somatic clone,eye disc & mitotic cell cycle | ectopic | somatic clone,intestinal stem cell,enteroendocrine cell,embryonic/larval neuromuscular junction | third instar larval stage,chaeta,supernumerary,trichogen cell,embryonic/larval fat body,somatic clone | third instar larval stage" DRSC11351 I 0.432825097 -1.781679599 0.212737057 0.312569377 -0.801507522 -0.471950549 FBgn0000229 bsk basket http://flybase.org/reports/FBgn0000229 "FBgn0015248, FBgn0032199" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR003527, InterPro:IPR008351 JUN kinase activity ; GO:0004705 | traceable author statement JUN kinase activity ; GO:0004705 | non-traceable author statement JUN kinase activity ; GO:0004705 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement JUN kinase activity ; GO:0004705 | inferred from sequence or structural similarity with HGNC:6886 inferred from direct assay JUN kinase activity ; GO:0004705 | inferred from mutant phenotype protein kinase activity ; GO:0004672 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Cka" "negative regulation of JUN kinase activity ; GO:0043508 |... mutant phenotype <> collateral sprouting of injured axon ; GO:0048674 |... mutant phenotype <> embryonic anterior midgut (ectodermal) morphogenesis ; GO:0048615 |... genetic interaction with puc <> dorsal closure ; GO:0007391 |... genetic interaction with Jra <> axon extension ; GO:0048675 |... mutant phenotype <> dorsal closure ; GO:0007391 | non-traceable author statement <> positive regulation of autophagy ; GO:0010508 |... mutant phenotype <> JNK cascade ; GO:0007254 | traceable author statement <> Wnt signaling pathway ; GO:0016055 | non-traceable author statement <> axon guidance ; GO:0007411 |... mutant phenotype <> response to oxidative stress ; GO:0006979 |... mutant phenotype <> cellular response to cadmium ion ; GO:0071276 |... direct assay <> MAPK cascade ; GO:0000165 | non-traceable author statement <> melanization defense response ; GO:0035006 |... mutant phenotype <> establishment of planar polarity ; GO:0001736 | non-traceable author statement <> wound healing ; GO:0042060 |... mutant phenotype <> dorsal appendage formation ; GO:0046843 |... mutant phenotype <> engulfment of apoptotic cell ; GO:0043652 |... mutant phenotype <> neuron projection morphogenesis ; GO:0048812 |... mutant phenotype <> cellular response to reactive oxygen species ; GO:0034614 |... direct assay <> micropyle formation ; GO:0046844 |... mutant phenotype <> positive regulation of neuron remodeling ; GO:1904801 |... mutant phenotype <> protein phosphorylation ; GO:0006468 | non-traceable author statement <> melanization defense response ; GO:0035006 |... genetic interaction with mei-9 <> antibacterial humoral response ; GO:0019731 |... direct assay <> cellular response to starvation ; GO:0009267 | NOT inferred from mutant phenotype <> mushroom body development ; GO:0016319 |... mutant phenotype <> neuron development ; GO:0048666 |... mutant phenotype <> protein phosphorylation ; GO:0006468 | traceable author statement <> ovarian follicle cell development ; GO:0030707 |... mutant phenotype <> regulation of gene expression ; GO:0010468 |... biological aspect of ancestor with PANTHER:PTN000622075 <> wound healing ; GO:0042060 |... direct assay <> JUN phosphorylation ; GO:0007258 |... mutant phenotype <> cellular response to oxidative stress ; GO:0034599 |... mutant phenotype <> long-term memory ; GO:0007616 |... genetic interaction with hiw <> imaginal disc fusion, thorax closure ; GO:0046529 |... mutant phenotype <> imaginal disc-derived male genitalia morphogenesis ; GO:0048803 |... mutant phenotype <> dorsal closure ; GO:0007391 | traceable author statement <> border follicle cell migration ; GO:0007298 |... genetic interaction with Pvr <> JNK cascade ; GO:0007254 |... direct assay <> wound healing, spreading of epidermal cells ; GO:0035313 |... mutant phenotype <> cellular response to arsenic-containing substance ; GO:0071243 |... direct assay <> response to heat ; GO:0009408 |... mutant phenotype <> determination of digestive tract left/right asymmetry ; GO:0071907 |... genetic interaction with puc <> positive regulation of border follicle cell migration ; GO:1903688 |... mutant phenotype <> axon guidance ; GO:0007411 |... direct assay" axon ; GO:0030424 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 "bsk, JNK, DJNK, jnk, dJNK, DBSK/JNK, D-JNK, CG5680, DJNK/bsk, JNK/SAPK, SAPKa, D-junk, Bsk, Junk, Jnk, P-JNK, BSK, pJNK, basket" "IPR000719:Protein kinase domain, IPR003527:Mitogen-activated protein (MAP) kinase, conserved site, IPR008271:Serine/threonine-protein kinase, active site, IPR008351:Mitogen-activated protein (MAP) kinase, JNK, IPR011009:Protein kinase-like domain" CG5680 11-Aug-17 DroID_v2017_08 "Drer\mapk8a, Drer\mapk8b, Drer\mapk9, Drer\mapk10" "Scer\HOG1, Scer\SMK1" "Cele\Y51B9A.9, Cele\jnk-1, Cele\kgb-1, Cele\C49C3.10, Cele\kgb-2" "Xtro\mapk8, Xtro\mapk10" "Mmus\Mapk10, Mmus\Mapk8, Mmus\Mapk9" "Hsap\MAPK9, Hsap\MAPK10, Hsap\MAPK8" " adult stage | male , embryonic stage | stage 6,7 , adult stage | female , larval stage | third instar , embryonic stage , embryonic stage && larval stage && pupal stage ,, embryonic stage | early , embryonic stage | stage >=8 " " posterior transverse furrow

, dorsal mesothoracic disc

, embryonic epidermis

, embryonic central nervous system

, embryonic peripheral nervous system

, fat body

, imaginal disc

, eye disc

, cephalic furrow

, anterior transverse furrow

,

ubiquitous , hemocyte

, embryonic brain

" "neuroanatomy defective,somatic clone,cell death defective,nutrition conditional,viable,fertile,chemical sensitive,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,wild-type,progressive,visible,wound healing defective,lethal,neurophysiology defective,planar polarity defective,stress response defective,RU486 conditional,conditional,long lived,oxidative stress response defective,starvation stress response defective,increased cell death,decreased cell growth,chemical resistant,short lived,heat sensitive" "Kenyon cell,somatic clone,axon | somatic clone,egg chamber,nutrition conditional,follicle cell,nurse cell,embryonic epidermis,dorsal,embryonic/first instar larval cuticle,axon & dorsal cluster neuron | somatic clone,stage 13 embryo,stage 14 embryo,stage 15 embryo,filamentous actin,amnioserosa,embryonic dorsal epidermis,anterior,neuroblast,progressive,alpha/beta Kenyon cell,gamma Kenyon cell,photoreceptor cell,ommatidium,embryo,axon | pupal stage | somatic clone,tract,dorsal closure embryo,germline clone,eye,lamina,neuron,eye photoreceptor cell,wing disc,thorax,medulla,axon & dorsal cluster neuronato.3.6,axoney-OK107,embryonic leading edge cell,embryonic abdominal segment,male genitalia,adult thorax,peripodial epithelium,embryonic/larval hemolymph | third instar larval stage,mesothoracic cleft,ectopic,bouton,neuromuscular junction | larval stage,synapse,segmental nerve,conditional,adult gut,RU486 conditional,autophagic vacuole | third instar larval stage | chemical conditional,embryonic/larval gut,chemical conditional,adult,embryonic/larval fat body,ventral furrow,intestinal stem cell,mesothoracic tergum,heat sensitive" FBgn0265575 yin yin http://flybase.org/reports/FBgn0265575 protein_coding_gene proton-dependent oligopeptide secondary active transmembrane transporter activity ; GO:0005427 | inferred from direct assay oligopeptide transport ; GO:0006857 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay "CG44402, yin, EG:EG0002.1, opt1, CG2913, opt, OPT1, Yin, OpT1, CG34336" "IPR018456:PTR2 family proton/oligopeptide symporter, conserved site, IPR000109:Proton-dependent oligopeptide transporter family, IPR004768:Oligopeptide transporter, IPR020846:Major facilitator superfamily domain" CG44402 11-Aug-17 DroID_v2017_08 "Drer\slc15a1a, Drer\slc15a4, Drer\slc15a1b, Drer\slc15a2, Drer\si:ch211-190o6.3" Scer\PTR2 "Cele\pept-1, Cele\pept-3, Cele\pept-2" "Xtro\slc15a4, Xtro\slc15a2" "Mmus\Slc15a3, Mmus\Slc15a5, Mmus\Slc15a4, Mmus\Slc15a1, Mmus\Slc15a2" "Hsap\SLC15A5, Hsap\SLC15A3, Hsap\SLC15A4, Hsap\SLC15A1, Hsap\SLC15A2" " adult stage | female , adult stage , adult stage && oogenesis stage | stage S10-11 , embryonic stage -- adult stage , adult stage && oogenesis stage , spermatogenesis && adult stage , embryonic stage | <3 hr , adult stage && oogenesis stage | stage >=S11 " " seminal receptacle

, nurse cell

, posterior adult hindgut | restricted

, ovary

, primary spermatocyte cyst | restricted

, adult midgut | restricted

, spermathecal duct

, oviduct

, adult head

, oocyte

" " adult stage , spermatogenesis && adult stage , adult stage && oogenesis stage | stage S9-14 , embryonic stage " " adult antennal nerve

, primary spermatocyte cyst | restricted

, oocyte

, mushroom body alpha-lobe

, oviduct

, adult fat body

, adult midgut | restricted

, spermathecal duct

, posterior adult hindgut | restricted

, yolk

, uterus

, neuropil

, adult rectal papilla | basal

, seminal receptacle

" FBgn0025800 Smox Smad on X http://flybase.org/reports/FBgn0025800 "FBgn0024186, FBgn0024304, FBgn0040171" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR013019 protein binding ; GO:0005515 | inferred from physical interaction with vis chromatin DNA binding ; GO:0031490 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001132, InterPro:IPR003619, InterPro:IPR013019, InterPro:IPR013790 transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from electronic annotation with InterPro:IPR013019 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis ; GO:0090256 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | non-traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype" transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR013019 "dSmad2, SMAD2, smox, dSMAD2, DSMAD2, smad2, Smad2, Sad, ted, sad, l(1)G0348, tmp, CG2262, Smox, DSmad2, dsmad2, SMOX, SmoX, Smad" "IPR001132:SMAD domain, Dwarfin-type, IPR003619:MAD homology 1, Dwarfin-type, IPR008984:SMAD/FHA domain, IPR013019:MAD homology, MH1, IPR013790:Dwarfin, IPR017855:SMAD domain-like" CG2262 11-Aug-17 DroID_v2017_08 "Drer\smad6a, Drer\si:dkey-239n17.4, Drer\smad3a, Drer\si:dkey-222b8.1, Drer\smad4a, Drer\smad3b, Drer\smad9, Drer\smad6b, Drer\smad2, Drer\smad1, Drer\smad5, Drer\gb:cr929477, Drer\smad7" - "Cele\daf-8, Cele\sma-3, Cele\sma-2" "Xtro\smad4.1, Xtro\smad1, Xtro\smad6, Xtro\smad4.2, Xtro\smad9, Xtro\smad3, Xtro\smad2, Xtro\smad7, Xtro\smad6.2" "Mmus\Smad7, Mmus\Smad1, Mmus\Smad2, Mmus\Smad3, Mmus\Smad5, Mmus\Smad9, Mmus\Smad4, Mmus\Smad6" "Hsap\SMAD7, Hsap\SMAD5, Hsap\SMAD2, Hsap\SMAD3, Hsap\SMAD6, Hsap\SMAD9, Hsap\SMAD4, Hsap\SMAD1" " embryonic stage -- adult stage , larval stage | third instar , adult stage | female , embryonic stage | stage >=6 , embryonic stage , embryonic stage | pre-blastoderm , embryonic stage | 0-2 hr " " imaginal disc

, mesoderm

, larval brain | restricted

, organism

" "neuroanatomy defective,germline clone,long lived,flight defective,progressive,RU486 conditional,visible,partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,cell growth defective,size defective,mitotic cell cycle defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,decreased cell size,lethal,viable,fertile" "abdominal segmental nerve,germline clone,adult somatic muscle,progressive,lysosome | progressiveMhc.PW,autophagic vacuoleMhc.PW,wing,chaeta,embryonic/larval anal pad,embryonic/larval brain,axon & eye photoreceptor cell,lamina anlage glial cell,medulla neuropil glial cell,larval inner optic anlage,larval outer optic anlage,gamma-lobe & neuron | somatic clone,gamma-lobe & dendrite | somatic clone,photoreceptor cell R7 & axon,photoreceptor cell R8 & axon,lamina,medulla neuropil,dorsal cluster neuron & axon | somatic clone,dorsal cluster neuron & neurite | somatic clone,protocerebrum,somatic clone,optic lobe,fascicle,photoreceptor cell R7,dorsal cluster neuron,wing disc,transmedullary neuron Tm20,wing blade,wing disc | larval stage,wing disc | third instar larval stage" DRSC18716 I -0.139699492 2.03074549 0.635918563 -1.243442561 0.248026268 -0.602609689 FBgn0000411 D Dichaete http://flybase.org/reports/FBgn0000411 "FBgn0010271, FBgn0010273, FBgn0010274, FBgn0010275, FBgn0010276, FBgn0013641, FBgn0014030" protein_coding_gene "DNA binding, bending ; GO:0008301 | inferred from direct assay mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with MGI:MGI:98364 transcription factor binding ; GO:0008134 | inferred from physical interaction with ind inferred from physical interaction with vnd transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "instar larval development ; GO:0002168 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with MGI:MGI:98364 dendrite guidance ; GO:0070983 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay central nervous system development ; GO:0007417 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay brain development ; GO:0007420 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype intracellular mRNA localization involved in pattern specification process ; GO:0060810 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype post-embryonic appendage morphogenesis ; GO:0035120 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "D, CG5893, fish, SOXB2.1, SOX70D, SOXDP, Sox70D, l(3)LG9, DM63, DM36, DM33, DM23, DM10, SOX70, Sry-rDM63, Sry-rDM36, Sry-rDM33, Sry-rDM23, Sry-rDM10, loD, Sox70, Sox B2-1" IPR009071:High mobility group box domain CG5893 11-Aug-17 DroID_v2017_08 "Drer\sox14, Drer\sox19a, Drer\sox4a, Drer\sox18, Drer\sox19b, Drer\tcf7l1b, Drer\sox1a, Drer\sox21a, Drer\sox2, Drer\lef1, Drer\sox12, Drer\sox4b, Drer\sox17, Drer\sox1b, Drer\sox11b, Drer\sox7, Drer\LOC103910042, Drer\sox21b, Drer\tcf7l1a, Drer\sox11a, Drer\sox3, Drer\sox8a" Scer\ROX1 "Cele\sox-2, Cele\hmg-3, Cele\hmg-4, Cele\sem-2, Cele\sox-3" "Xtro\sox1, Xtro\sox21, Xtro\sox17b.1, Xtro\sox17a, Xtro\sox18, Xtro\sox14, Xtro\sox7, Xtro\sox2, Xtro\sox3, Xtro\sox17b.2" "Mmus\Sox18, Mmus\Sox8, Mmus\Sox7, Mmus\Sox1, Mmus\Sox12, Mmus\Sox11, Mmus\Sox14, Mmus\Sox2, Mmus\Sox17, Mmus\Sox9, Mmus\Sox4, Mmus\Sox21, Mmus\Sox3, Mmus\Sox15" "Hsap\SOX11, Hsap\SOX17, Hsap\SOX18, Hsap\SOX21, Hsap\SOX4, Hsap\SOX1, Hsap\SOX2, Hsap\SOX3, Hsap\SOX7, Hsap\SOX14, Hsap\SOX12" " embryonic stage | stage 6 , embryonic stage | embryonic cycle 13 , embryonic stage | stage 13 , embryonic stage | embryonic cycle 14 , embryonic stage | extended germ band , embryonic stage | stage 6-8 , embryonic stage | early , embryonic stage | stage 4 " " ventral neurogenic region | restricted

, organism | 10-70% egg length

, embryonic brain

, embryonic/larval hindgut

,

50% egg length , ventral neurogenic region | medial

, organism | 10-30% egg length

, ventral nerve cord | restricted

, embryonic/larval pharynx

, procephalic neurogenic region

" "viable,fertile,neuroanatomy defective,visible,dominant,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,germline clone,partially lethal - majority die,eye color defective,some die during pupal stage,partially lethal - majority live" "wing,proximal,wing vein L3,medial costal vein,alula,embryonic/larval central nervous system,commissure | embryonic stage,tract | embryonic stage,longitudinal connective | embryonic stage,axon | embryonic stagesim.P3.7,axon | embryonic stagepros.C20,posterior,wing hinge,embryonic segment,embryonic head,ventral nerve cord commissure,longitudinal connective,midline glial cell,RP2 motor neuron,supernumerary,aCC neuron,pCC neuron,EL neuron,neuroblast NB5-3,embryonic epidermis,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,neuroblast NB6-1,neuroblast NB4-1,first segment of antenna,somatic clone,adult cuticle & adult head | somatic clone,tibia,tarsal segment,presumptive embryonic/larval central nervous system,neuroblast NB1-1,dorsal appendage,germline clone,chorion | germline clone,embryonic abdominal segment,embryonic abdominal segment 1,embryonic abdominal segment 4,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,anterior,abdominal segment,denticle belt,larval hindgut & embryo & cellfz-GS1a),hindgut,embryonic tritocerebrum,embryonic deuterocerebrum,sensillum campaniformium of dorsal radius Sc25,sensillum campaniformium of dorsal radius Sc12,sensillum campaniformium of ventral radius Sc5,haltere,macrochaeta & adult thorax,eye,ommatidium,interommatidial bristle,leg,arista,third segment of antenna,pigment cell,eye-antennal disc,antenna,macrochaeta,ectopic,tarsal segment 2,tarsal segment 3,tarsal segment 4,distal,morphogenetic furrow,anterior commissure,posterior commissure,trichogen cell,mesothoracic tergum,adult antennal lobe projection neuron,dendrite,axon,local interneuron of adult antennal lobe,adult olfactory receptor neuron Or47b,adult olfactory receptor neuron Or88a" FBgn0039234 nct nicastrin http://flybase.org/reports/FBgn0039234 protein_coding_gene endopeptidase activity ; GO:0004175 | inferred from biological aspect of ancestor with PANTHER:PTN000473190 cytoskeleton organization ; GO:0007010 | inferred from mutant phenotype membrane protein ectodomain proteolysis ; GO:0006509 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000473190 lateral inhibition ; GO:0046331 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype regulation of compound eye photoreceptor development ; GO:0045314 | inferred from mutant phenotype R8 cell development ; GO:0045463 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype inferred from genetic interaction with N "gamma-secretase complex ; GO:0070765 | inferred from physical interaction with aph-1, pen-2, Psn late endosome ; GO:0005770 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000473190 plasma membrane ; GO:0005886 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay" "Nct, CG7012, S5A, agro, Nic, nct, dNct, nic, ST96B" IPR008710:Nicastrin CG7012 11-Aug-17 DroID_v2017_08 Drer\ncstn - Cele\aph-2 Xtro\ncstn Mmus\Ncstn Hsap\NCSTN "viable,visible,lethal,recessive,germline clone,neurogenic phenotype,wild-type,lethal - all die before end of larval stage,some die during larval stage,partially lethal,somatic clone,increased cell number,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell number" "eye,embryonic epidermis,germline clone,presumptive embryonic/larval nervous system,wing,somatic clone,wing vein,wing disc,wing margin,wing margin bristle,follicle cell,oocyte,cell non-autonomous,germinal vesicle | cell non-autonomous,cytoskeleton & follicle cell | somatic clone,larva,sensory mother cell & dorsal mesothoracic disc,presumptive embryonic/larval central nervous system,microchaeta,neuroblast,adult head,external sensory organ precursor cell,supernumerary,antennal disc,eye disc,eye photoreceptor cell,ventral thoracic disc,photoreceptor cell R8,nucleus | somatic clone | wandering third instar larval stage" FBgn0005561 sv shaven http://flybase.org/reports/FBgn0005561 "FBgn0003468, FBgn0003649, FBgn0004541, FBgn0020913" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" neuron development ; GO:0048666 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype regulation of compound eye cone cell fate specification ; GO:0042682 | inferred from mutant phenotype inferred from genetic interaction with ttk positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of retinal cone cell fate specification ; GO:0042673 | inferred from mutant phenotype inferred from genetic interaction with pros regulation of R7 cell differentiation ; GO:0045676 | inferred from mutant phenotype inferred from genetic interaction with pros compound eye cone cell fate commitment ; GO:0042676 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "Pax2, D-pax-2, spa, D-Pax2, Dpax2, Pax2/5/8, PAX2, d-Pax2, shaven/sparkling, D-pax2, dPax2, en(lz)4G/I, pax2/sparkling, spa-sv, Dpax-2, dPax258, DPax-2, Cat, pol, l(4)40, Pax258, CG11049, sv, Sv, DPax2" "IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG11049 11-Aug-17 DroID_v2017_08 "Drer\pax10, Drer\arxa, Drer\pax9, Drer\pax6b, Drer\pax7a, Drer\pax1b, Drer\pax1a, Drer\pax7b, Drer\pax3a, Drer\pax6a, Drer\pax8, Drer\pax2a, Drer\pax5, Drer\arxb, Drer\pax2b" - "Cele\egl-38, Cele\pax-2, Cele\alr-1, Cele\vab-3, Cele\pax-1" "Xtro\pax7, Xtro\pax6, Xtro\arx, Xtro\pax2, Xtro\pax1, Xtro\pax9, Xtro\pax3, Xtro\pax8, Xtro\pax5" "Mmus\Pax4, Mmus\Pax3, Mmus\Pax5, Mmus\Pax8, Mmus\Pax2, Mmus\Pax6, Mmus\Pax1, Mmus\Pax7, Mmus\Pax9, Mmus\Arx" "Hsap\ARX, Hsap\PAX4, Hsap\PAX3, Hsap\PAX6, Hsap\PAX5, Hsap\PAX2, Hsap\PAX7, Hsap\PAX1, Hsap\PAX8, Hsap\PAX9" " larval stage , embryonic stage " " ventral nerve cord

, morphogenetic furrow | posterior to

, dorsal mesothoracic disc

, larval brain

, antennal disc

, embryonic nervous system

, eye disc

, ventral thoracic disc

, peripheral nervous system

" " pupal stage , larval stage , pupal stage | early " " mechanosensory chaeta

, cone cell | precursor

, eye disc

, primary pigment cell | precursor

" "visible,recessive,uncoordinated,sterile,behavior defective,lethal,increased cell death,wild-type,viable,dominant,fertile,cold sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,short lived,somatic clone,heat sensitive,lethal - all die before end of P-stage,some die during pharate adult stage" "eye,cone cell,eye photoreceptor cell,inter-ommatidial precursor cell,supernumerary,pseudocone,lens,ommatidium,interommatidial bristle,macrochaeta,scutum & macrochaeta,scutum & microchaeta,scutum & macrochaeta & trichogen cell,scutum & macrochaeta & tormogen cell,anterior dorsocentral bristle & trichogen cell,posterior dorsocentral bristle & tormogen cell,microchaeta,chaeta,scutum & microchaeta & trichogen cell,rhabdomere,primary pigment cell,pigment cell,eye disc,somatic clone,anterior dorsocentral bristle & tormogen cell,trichogen cell,thecogen cell,wing,posterior,unguis,retina,adult head,antenna,external sensory organ,ectopic,tormogen cell,scutum & macrochaeta & trichogen cell | conditional tshs.PB,scutum & macrochaeta & tormogen cell | conditional tshs.PB,head bristle & trichogen cell | conditional tshs.PB,head bristle & tormogen cell | conditional tshs.PB,orbital bristle & trichogen cell | conditional tshs.PB,scutum & microchaeta & trichogen cell | conditional tshs.PB,head bristle & trichogen cellBx-MS1096,head bristle & tormogen cellBx-MS1096,scutum & microchaeta & trichogen cellBx-MS1096,scutum & microchaeta & tormogen cellBx-MS1096,rhabdomere R7" FBgn0260618 2L1682 - http://flybase.org/reports/FBgn0260618 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1682 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0003733 tor torso http://flybase.org/reports/FBgn0003733 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from direct assay protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from sequence or structural similarity" "anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement terminal region determination ; GO:0007362 | non-traceable author statement pole cell migration ; GO:0007280 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement torso signaling pathway ; GO:0008293 | traceable author statement cell fate determination ; GO:0001709 | traceable author statement negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype gastrulation ; GO:0007369 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay Malpighian tubule morphogenesis ; GO:0007443 | traceable author statement chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from mutant phenotype negative phototaxis ; GO:0046957 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG1389, Tor, splc, tor, Torso, TOR, torso" "IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR003961:Fibronectin type III, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR013783:Immunoglobulin-like fold, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG1389 11-Aug-17 DroID_v2017_08 "Drer\styk1, Drer\fgfr3, Drer\flt1, Drer\met, Drer\mst1ra, Drer\fgfr1a, Drer\pdgfrb, Drer\si:ch73-206d17.1, Drer\si:dkey-14o18.6, Drer\fgfrl1b, Drer\si:ch211-167j9.5, Drer\fgfrl1a, Drer\csf1ra, Drer\fgfr4, Drer\kdrl, Drer\pdgfrl, Drer\tek, Drer\tada2b, Drer\fgfr2, Drer\kitb, Drer\csf1rb, Drer\pdgfra, Drer\LOC569566, Drer\kita, Drer\kdr, Drer\tie1, Drer\ret, Drer\flt3, Drer\flt4, Drer\mst1rb" - "Cele\C24G6.2, Cele\R09D1.12, Cele\ver-4, Cele\kin-30, Cele\old-1, Cele\F11E6.8, Cele\kin-16, Cele\R151.1, Cele\kin-15, Cele\egl-15, Cele\F09A5.2, Cele\old-2, Cele\kin-9, Cele\kin-23, Cele\T08D2.7, Cele\F09G2.1" "Xtro\tie1, Xtro\fgfr3, Xtro\fgfr1, Xtro\met, Xtro\flt1, Xtro\csf1r, Xtro\pdgfra, Xtro\fgfr4, Xtro\fgfrl1, Xtro\ret, Xtro\tada2b, Xtro\tek, Xtro\pdgfrl.2, Xtro\mst1r, Xtro\fgfr2, Xtro\pdgfrl, Xtro\styk1, Xtro\kdr, Xtro\flt4" "Mmus\Fgfr1, Mmus\Pdgfrb, Mmus\Kit, Mmus\Pdgfrl, Mmus\Kdr, Mmus\Fgfr2, Mmus\Tek, Mmus\Flt4, Mmus\Ret, Mmus\Met, Mmus\Fgfr3, Mmus\Tie1, Mmus\Fgfrl1, Mmus\Csf1r, Mmus\Tada2b, Mmus\Fgfr4, Mmus\Styk1, Mmus\Flt3, Mmus\Mst1r, Mmus\Flt1, Mmus\Pdgfra" "Hsap\KDR, Hsap\TADA2B, Hsap\FGFR4, Hsap\RET, Hsap\FGFR2, Hsap\KIT, Hsap\TIE1, Hsap\TEK, Hsap\FGFR3, Hsap\PDGFRB, Hsap\FLT4, Hsap\PDGFRL, Hsap\FLT1, Hsap\PDGFRA, Hsap\FGFRL1, Hsap\FLT3, Hsap\STYK1, Hsap\MET, Hsap\FGFR1, Hsap\MST1R, Hsap\CSF1R" " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >S10 , embryonic stage | early , adult stage | female , embryonic stage " " germarium

, oocyte

,

ubiquitous ,

medial , nurse cell

" " embryonic stage , embryonic stage | syncytial blastoderm " "

posterior | gradient ,

medial " "viable,fertile,neurophysiology defective,phototaxis defective,lethal,maternal effect,recessive,wild-type,partially lethal - majority die,large body,developmental rate defective,terminal phenotype,germline clone,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,female sterile,hypoactive,dominant,cold sensitive,female sterile germline-dependent,hyperactive,size defective,heat sensitive,visible,small body,male limited" "ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,abdominal segment 9,abdominal segment 10,telson,labrum,ocular segment,cephalic furrow,cephalopharyngeal skeleton,filzkorper,embryonic/larval anus,embryonic/larval posterior spiracle,germline cell,embryonic epidermis,embryonic labial segment,dorsal bridge,embryonic abdominal segment 7,embryonic abdominal segment 8,embryo,germline clone,maternal effect,stomatogastric nervous system,embryonic/larval labral segment sense organ,dorsopharyngeal organ,pharyngeal monoscolopidial chordotonal organ,embryonic/larval optic lobe,embryonic/larval brain,labral segment,embryonic/larval esophagus,embryonic/larval labral nerve,adult labral sense organ,head,abdominal segment 11,embryonic/first instar larval cuticle,embryonic labral segment,posterior midgut primordium,extended germ band embryo,embryonic head,endoderm,visceral mesoderm,posterior,denticle belt,ectopic,cold sensitive,embryonic abdominal segment,embryonic telson,embryonic anal pad,abdominal 11 anal tuft,embryonic/larval midgut,pole cell,salivary gland common duct primordium,gastrula embryo,abdomen,abdominal 8 ventral denticle belt,heat sensitive,anterior midgut primordium,embryonic abdominal segment 4,embryonic thoracic segment,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 5,abdominal segment,wing,pupa" FBgn0003145 prd paired http://flybase.org/reports/FBgn0003145 - protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay DNA binding ; GO:0003677 | non-traceable author statement" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay periodic partitioning by pair rule gene ; GO:0007366 | traceable author statement transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement periodic partitioning by pair rule gene ; GO:0007366 | non-traceable author statement" nucleus ; GO:0005634 | non-traceable author statement "prd, Prd, pr, CG6716, PRD" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG6716 11-Aug-17 DroID_v2017_08 "Drer\pax6a, Drer\pax2a, Drer\pax5, Drer\mxtx2, Drer\pax7a, Drer\pax1b, Drer\pax3a, Drer\mxtx1, Drer\pax9, Drer\pax3b, Drer\pax7b, Drer\arxb, Drer\pax2b, Drer\pax8, Drer\pax10, Drer\mixl1, Drer\pax6b, Drer\pax1a, Drer\pax4, Drer\arxa" - "Cele\ceh-18, Cele\pax-3, Cele\alr-1, Cele\egl-38, Cele\pax-2, Cele\vab-3, Cele\pax-1" "Xtro\pax1, Xtro\mixer, Xtro\pax6, Xtro\pax8, Xtro\pax7, Xtro\bix1.1, Xtro\pax2, Xtro\arx, Xtro\pax9, Xtro\pax5, Xtro\sia1, Xtro\shox2, Xtro\mix1, Xtro\pax3" "Mmus\Cphx1, Mmus\Cphx3, Mmus\Duxbl3, Mmus\Duxbl2, Mmus\Pax7, Mmus\Pax1, Mmus\Pax3, Mmus\Shox2, Mmus\Nobox, Mmus\Mixl1, Mmus\Pax6, Mmus\Duxbl1, Mmus\Pax5, Mmus\Pax4, Mmus\Pax2, Mmus\Pax8, Mmus\Pax9, Mmus\Arx" "Hsap\PAX5, Hsap\PAX9, Hsap\PAX1, Hsap\SHOX2, Hsap\SHOX, Hsap\PAX6, Hsap\DUX4, Hsap\PAX4, Hsap\PAX2, Hsap\MIXL1, Hsap\ARX, Hsap\PAX3, Hsap\PAX7, Hsap\DUXA, Hsap\PAX8" " embryonic stage | syncytial blastoderm , embryonic stage | cellular blastoderm , embryonic stage "

segment polarity " embryonic stage | stage 4-5 , adult stage | male , embryonic stage | early , embryonic stage | stage 11 , embryonic stage | stage 7-8 , embryonic stage | stage >11 " " organism | anterior & dorsal

, male accessory gland main cell

, organism | 60-80% egg length

, embryonic maxillary segment

,

segment polarity , embryonic labial segment

, embryonic mandibular segment

, male accessory gland secondary cell

,

odd pair rule , embryonic central nervous system | restricted

, embryonic labral segment

" "pair rule phenotype,male sterile,wild-type,lethal,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,heat sensitive,visible,partially lethal - majority die,some die during pupal stage" "RP2 motor neuron,EL neuron,U neuron,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 2 ventral denticle belt,cuticle,denticle belt,male accessory gland,abdomen & cuticle & adult,larval midgut & embryo & epidermis,heart primordium,embryonic abdominal segment 1 & muscle founder cell,embryonic abdominal segment 3 & muscle founder cell,embryonic abdominal segment 1 & cardioblast,embryonic abdominal segment 3 & cardioblast,embryonic labial segment,embryonic/larval cuticle,cephalic furrow,prothoracic ventral denticle belt,metathoracic ventral denticle belt,embryonic/first instar larval cuticle & abdominal segment 1,embryonic/first instar larval cuticle & abdominal segment 3,embryonic/first instar larval cuticle & abdominal segment 5,embryonic/first instar larval cuticle & abdominal segment 7,embryonic/first instar larval cuticle & mesothoracic segment,syncytial blastoderm embryo,eye,adult head,antenna" FBgn0015396 jumu jumeau http://flybase.org/reports/FBgn0015396 "FBgn0010887, FBgn0013264, FBgn0015660" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001795516 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay" "nucleolus organization ; GO:0007000 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement chromatin organization ; GO:0006325 | traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype regulation of cell division ; GO:0051302 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN001795516 asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype" polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay chromatin ; GO:0000785 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay euchromatin ; GO:0000791 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "Dom, Dmjumu, jumu/Dom, Scim31, CG4029, Whn, Dwhn, l(3)06439, l(3)06142, 5295, E(var)631, jumu, Jumu, Jumeau, jumeaux, jumeau" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG4029 11-Aug-17 DroID_v2017_08 "Drer\zgc:171734, Drer\foxn1, Drer\foxn4" Scer\FHL1 - "Xtro\foxr1, Xtro\foxn1, Xtro\foxn4" "Mmus\Foxn1, Mmus\Foxn4, Mmus\Foxr2, Mmus\Foxr1" "Hsap\FOXN1, Hsap\FOXN4, Hsap\FOXR1, Hsap\FOXR2" "viable,immune response defective,enhancer of variegation,dominant,suppressor of variegation,lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,fertile,some die during embryonic stage,neuroanatomy defective,heat sensitive,meiotic cell cycle defective,mitotic cell cycle defective,partially lethal - majority die,wild-type" "polytene chromosomeG61,nucleolusG61,embryonic/larval salivary gland,nucleolusSgs4.PH,euchromatinSgs4.PH,polytene chromosomeSgs4.PH,hemocyte,plasmatocyte,wing,wing margin bristle,wing margin,posterior,wing hair,wing vein L5,macrochaeta,eye,ommatidium,rhabdomere,polytene chromosome,nucleolus,RP2 motor neuron,ectopic,embryonic/larval cardial cell,embryonic head,embryo,wing disc,somatic clone,embryonic/larval neuron,mitosis & nuclear chromosome,heat sensitive,photoreceptor cell,interommatidial bristle,supernumerary,adult thoracic sensillum,wing vein,RP2sib neuron,embryonic/larval pericardial cell" DRSC16651 K 0.351399047 0.470103079 0.27236188 -1.325118169 1.497283943 1.994049592 FBgn0013263 Trl Trithorax-like http://flybase.org/reports/FBgn0013263 "FBgn0036445, FBgn0053261, FBgn0005691, FBgn0010008, FBgn0010418, FBgn0011024, FBgn0025220" protein_coding_gene "protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KRI2 protein binding ; GO:0005515 | inferred from physical interaction with Ssrp DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P17789 chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 transcription factor binding ; GO:0008134 | inferred from physical interaction with bip2 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay POZ domain binding ; GO:0031208 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:Q08605" "nuclear division ; GO:0000280 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype dosage compensation ; GO:0007549 | inferred from mutant phenotype protein oligomerization ; GO:0051259 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay nucleosome organization ; GO:0034728 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with Hsf positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype positive regulation of phosphorylation of RNA polymerase II C-terminal domain ; GO:1901409 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype inferred from genetic interaction with bip2 positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement chromatin organization ; GO:0006325 | non-traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from direct assay chromatin assembly ; GO:0031497 | inferred from direct assay" euchromatin ; GO:0000791 | inferred from direct assay chromatin ; GO:0000785 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay pericentric heterochromatin ; GO:0005721 | traceable author statement inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "GAF, CG9343, GAGA, trl, Trl-GAGA, E(var)3-trl, Nc70F, Adf-2-519, TfGAGA/Adf-2, CG33261, E(var)62, Gaga, Gaf, Adf-2, Adf2, NC70F, l(3)s2325, anon-EST:fe2E12, Trl, gaga, TRL, GAGA factor, LBC" "IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type, IPR000210:BTB/POZ domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR015318:Zinc finger, GAGA-binding factor" CG33261 11-Aug-17 DroID_v2017_08 "Drer\zbtb49, Drer\zbtb8b, Drer\hic2, Drer\bcl6ab" - - "Xtro\hic1, Xtro\zbtb49, Xtro\gzf1, Xtro\zbtb2, Xtro\zbtb43, Xtro\znf238.2, Xtro\zbtb7b, Xtro\hic2" "Mmus\Zbtb44, Mmus\Nacc2, Mmus\Zbtb43, Mmus\Zbtb9, Mmus\Zbtb17, Mmus\Zbtb21, Mmus\Zbtb42, Mmus\Zbtb16, Mmus\Bcl6b, Mmus\Zbtb39, Mmus\Zbtb49" "Hsap\NACC2, Hsap\ZBTB44, Hsap\BCL6B, Hsap\ZBTB46, Hsap\ZBTB3, Hsap\ZBTB2, Hsap\BCL6, Hsap\ZBTB40, Hsap\NACC1, Hsap\ZBTB49, Hsap\MYNN, Hsap\ZBTB17, Hsap\ZBTB48, Hsap\BTBD18, Hsap\ZBTB14, Hsap\ZBTB38" "partially lethal - majority die,heat sensitive,male fertile,female sterile,female semi-sterile,female sterile germline-dependent,germline clone,lethal,recessive,homeotic,semi-fertile,maternal effect,some die during embryonic stage,conditional,visible,dominant,lethal - all die before end of larval stage,some die during larval stage,enhancer of variegation,male,viable,female,reduced,meiotic cell cycle defective,non-suppressor of variegation" "egg,dorsal appendage,ovary,egg chamber,oocyte,nurse cell,actin filament,abdominal segment 5,ectopic,abdominal segment 6,wing margin,mitosis & nuclear chromosome[-],chromatin[-],mitosis & nuclear chromosome,chromatin,wing,eye,sex comb,microchaeta & abdominal segment 6 | ectopic,imaginal disc,micropyle,denticle belt,embryo,anterior,microchaeta,somatic clone,macrochaeta,proboscis,maxillary palpus,mesothoracic tergum,adult abdominal segment 6,adult abdominal segment 5,trichogen cell" FBgn0004861 ph-p polyhomeotic proximal http://flybase.org/reports/FBgn0004861 "FBgn0003077, FBgn0029600, FBgn0029601" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012313 protein binding ; GO:0005515 | inferred from physical interaction with barr protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VHA0 core promoter binding ; GO:0001047 | inferred from direct assay chaperone binding ; GO:0051087 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay DNA topoisomerase binding ; GO:0044547 | inferred from physical interaction with Top2 "response to ecdysone ; GO:0035075 | inferred from mutant phenotype ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from genetic interaction with esc inferred from genetic interaction with Pc inferred from genetic interaction with Scm central nervous system neuron development ; GO:0021954 | inferred from mutant phenotype germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay PRC1 complex ; GO:0035102 | inferred from direct assay PRC1 complex ; GO:0035102 | traceable author statement nucleolus ; GO:0005730 | inferred from direct assay "Ph, PH, ph, CG18412, PH-p, EG:87B1.5, CG18414, php, ph[P], ph-P, phm, ph-p, PHP, dPh, Ph-p, ph[p], PhP, ph-proximal" "IPR001660:Sterile alpha motif domain, IPR012313:Zinc finger, FCS-type, IPR013761:Sterile alpha motif/pointed domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical" CG18412 11-Aug-17 DroID_v2017_08 "Drer\samd11, Drer\scml4, Drer\phc1, Drer\si:ch211-230g15.5, Drer\sfmbt2, Drer\phc3, Drer\phc2b, Drer\samd7, Drer\phc2a, Drer\sfmbt1" - "Cele\sor-3, Cele\K02F6.7" "Xtro\phc3, Xtro\phc2" "Mmus\Phc2, Mmus\Phc3, Mmus\Sfmbt1, Mmus\Phc1, Mmus\Scml4, Mmus\Sfmbt2, Mmus\Samd7, Mmus\Samd11" "Hsap\PHC3, Hsap\SCML1, Hsap\SCML2, Hsap\SFMBT1, Hsap\SAMD7, Hsap\SFMBT2, Hsap\PHC1, Hsap\SCML4, Hsap\SAMD11, Hsap\PHC2" " adult stage && oogenesis stage | stage S1-10 , embryonic stage -- adult stage , embryonic stage | cellular blastoderm , embryonic stage , larval stage | third instar , embryonic stage | stage >=12 , adult stage && oogenesis stage , embryonic stage | blastoderm , embryonic stage | stage 8-11 " " follicle cell

,

50-90% egg length , ectoderm | striped

, ventral thoracic disc

, embryonic central nervous system

, dorsal metathoracic disc

,

ubiquitous , germarium

, nurse cell

, dorsal mesothoracic disc

,

50-80% egg length ,

10-30% egg length , eye-antennal disc

, parasegment | restricted

, germ band

" " larval stage | third instar , embryonic stage | late , embryonic stage " " eye-antennal disc

, dorsal mesothoracic disc

, sensillum campaniformium

, embryonic peripheral nervous system

, dorsal metathoracic disc

, ventral thoracic disc

, cell body

,

ubiquitous , embryonic central nervous system

" "visible,recessive,homeotic,viable,mitotic cell cycle defective,partially lethal - majority die,lethal,wild-type,neuroanatomy defective,somatic clone,eye color defective,dominant,suppressor of variegation,heat sensitive,some die during pupal stage,tumorigenic,neoplasia,large body,developmental rate defective,small body,lethal - all die before end of pupal stage" "sex comb,mesothoracic leg,metathoracic leg,abdominal segment 6,ovary,interfollicle cell,egg chamber,germarium region 2b,germarium region 3,germline cyst,wing,haltere,ectopic,germarium,polar follicle cell,wing disc,eye,optic lobe neuron,somatic clone,Kenyon cell,antennal lobe,dorsal cluster neuron,ellipsoid body,genitalia,anaphase | embryonic stage,telophase | embryonic stage,nucleus | embryonic stage,posterior compartment,abdominal segment 1,abdominal segment 4,humerus,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,adult abdominal segment 4,adult abdominal segment 5,larval abdominal segment 4,larval abdominal segment 5,prothoracic leg,sex comb tooth,mesothoracic leg & sex comb | ectopic,wing disc posterior compartment,heat sensitive,mouth hooks,pupa" FBgn0004618 gl glass http://flybase.org/reports/FBgn0004618 "FBgn0001107, FBgn0002960, FBtr0083584, FBpp0083005, FBtr0083585, FBpp0083006" protein_coding_gene "DNA binding ; GO:0003677 | inferred from mutant phenotype transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity" "compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype ring gland development ; GO:0035271 | inferred from mutant phenotype entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype circadian temperature homeostasis ; GO:0060086 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype response to red light ; GO:0010114 | inferred from mutant phenotype compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "gl, SY3-3, SS3-2, Glass, E(sina)5, none, rh, CG7672, gla, Gla, glass, Gl" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7672 11-Aug-17 DroID_v2017_08 "Drer\gfi1aa, Drer\LOC799968, Drer\gfi1b, Drer\prdm12b, Drer\gfi1ab" Scer\ZAP1 "Cele\lin-29, Cele\che-1, Cele\C46E10.9, Cele\egrh-3" - "Mmus\Zfp263, Mmus\Zfp663, Mmus\Zscan4f, Mmus\Zkscan4, Mmus\Zscan4d, Mmus\Zfp771, Mmus\Vezf1, Mmus\Prdm12, Mmus\Zscan22, Mmus\Zscan2, Mmus\Zscan4b, Mmus\Zfp606, Mmus\Zfp189, Mmus\Zfp719, Mmus\Zfp286, Mmus\Zfp768, Mmus\E430018J23Rik, Mmus\Zscan4c, Mmus\Gfi1, Mmus\Zfp24, Mmus\Gfi1b" "Hsap\ZNF764, Hsap\ZKSCAN5, Hsap\PRDM12, Hsap\ZNF500, Hsap\HIC2, Hsap\GFI1, Hsap\GFI1B, Hsap\ZNF683, Hsap\VEZF1, Hsap\HIC1" " pupal stage , adult stage , larval stage | third instar " " adult head

, morphogenetic furrow

, eye-antennal disc

" " larval stage | third instar , larval stage | third instar && P-stage , embryonic stage , larval stage | third instar && P " " morphogenetic furrow

, secondary pigment cell

, brain | restricted

, eye-antennal disc

, cone cell

, morphogenetic furrow | vicinity of

, larval brain | restricted

, Bolwig's organ

, ocellus

, eye disc posterior to the morphogenetic furrow

, organism | restricted

, primary pigment cell

, photoreceptor cell

, tertiary pigment cell

" "visible,eye color defective,viable,lethal,heat sensitive,wild-type,recessive,good,fertile,locomotor behavior defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,auditory perception defective,neurophysiology defective,locomotor rhythm defective,behavior defective,reduced" "retina,ommatidium,eye photoreceptor cell,ocellus lens,eye,ocellus,rhabdomere,lamina,ocellus retinula cell,pigment cell,ocellus pigment granule,secondary pigment cell,tertiary pigment cell,embryonic/larval salivary gland,heat sensitive,retina & fascicle | somatic clone,photoreceptor cell R7,corpus cardiacum primordium,Bolwig organ primordium,Bolwig nerve,Bolwig organ,ring gland,embryonic/larval corpus cardiacum,photoreceptor cell,larval LN period neuron,serotonergic LP1 neuron,optic nerve,retina & axon,primary pigment cell,eyelet,photoreceptor cell & axon,eyelet photoreceptor,medulla,optic lobe,Pdf neuron,DN1 neuron" FBgn0002431 hyd hyperplastic discs http://flybase.org/reports/FBgn0002431 FBgn0002317 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from electronic annotation with InterPro:IPR024725 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002004 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003126 ubiquitin-ubiquitin ligase activity ; GO:0034450 | inferred from sequence or structural similarity with HGNC:16806 spermatogenesis ; GO:0007283 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | non-traceable author statement female gonad development ; GO:0008585 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:16806 imaginal disc growth ; GO:0007446 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | non-traceable author statement male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype spermatid nucleus differentiation ; GO:0007289 | inferred from mutant phenotype compound eye development ; GO:0048749 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "HYD, l(3)c43, c43, l(3)C43-3, l[[3]]c43, l(3)C43, l(3)SG33, l(3)85Ea, CG9484, hyd, UBE 3A, Hyd, NP_524296.2, UBR5" "IPR015940:Ubiquitin-associated domain, IPR000569:HECT domain, IPR002004:Polyadenylate-binding protein/Hyperplastic disc protein, IPR003126:Zinc finger, UBR-type, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR024725:E3 ubiquitin ligase EDD, ubiquitin-associated domain" CG9484 11-Aug-17 DroID_v2017_08 Drer\ubr5 Scer\TOM1 "Cele\ubr-4, Cele\ubr-5" Xtro\ubr5 Mmus\Ubr5 Hsap\UBR5 embryonic stage -- adult stage embryonic stage -- adult stage "lethal - all die before end of larval stage,some die during larval stage,viable,cytokinesis defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage,heat sensitive,lethal,hyperplasia,male sterile,visible,somatic clone,increased cell death,female sterile,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die" "primary spermatocyte cyst,elongation stage spermatid,nucleus,meiotic primary spermatocyte,centrosome,spindle,spermatogonium,imaginal disc,wing disc,posterior compartment,somatic clone,eye disc,cell non-autonomous,eye,photoreceptor cell,ectopic,ovary,eye-antennal disc,heat sensitive,haltere disc,leg,wing,haltere,antenna,egg,germline clone,testis,mesothoracic tergum" DRSC28294 K -0.336435446 -1.28369594 0.468662914 -0.457280126 -2.094176548 -0.811346785 FBgn0010105 comm commissureless http://flybase.org/reports/FBgn0010105 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI3 protein binding ; GO:0005515 | inferred from physical interaction with Nedd4 WW domain binding ; GO:0050699 | inferred from physical interaction with Nedd4 WW domain binding ; GO:0050699 | inferred from direct assay axon guidance ; GO:0007411 | traceable author statement axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype positive regulation of receptor internalization ; GO:0002092 | inferred from mutant phenotype endocytosis ; GO:0006897 | traceable author statement dendrite morphogenesis ; GO:0048813 | traceable author statement receptor internalization ; GO:0031623 | inferred from direct assay axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with fra axon midline choice point recognition ; GO:0016199 | NOT inferred from mutant phenotype neuron recognition ; GO:0008038 | inferred from mutant phenotype nervous system development ; GO:0007399 | traceable author statement synapse assembly ; GO:0007416 | traceable author statement axon midline choice point recognition ; GO:0016199 | traceable author statement synapse assembly ; GO:0007416 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay vesicle ; GO:0031982 | inferred from direct assay endocytic vesicle ; GO:0030139 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay "CG17943, comm, Comm" IPR031878:Commissureless CG17943 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 12-16 , embryonic stage | stage 10 , embryonic stage | stage 6-10 , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | stage >=10 " " ventral midline | restricted

, ganglion mother cell

,

segment polarity , midline glial cell

, neuroblast

, visceral mesoderm

, organism | pair rule

, epidermis

, embryonic central nervous system | presumptive | segmentally repeated pattern

" " embryonic stage | stage 10 , embryonic stage | stage 12-16 , embryonic stage , embryonic stage | stage 6-10 , embryonic stage | stage >=10 , embryonic stage | stage 5 " " neuroblast

, ventral midline | restricted

, ventral nerve cord commissure

,

segment polarity , midline glial cell

, neuron

, visceral mesoderm

, embryonic central nervous system | presumptive | segmentally repeated pattern

, organism | pair rule

, epidermis | longitudinal stripes

, ganglion mother cell

" "neuroanatomy defective,lethal,recessive,uncoordinated,lethal - all die before end of larval stage,some die during larval stage,cell autonomous,somatic clone,viable" "embryonic/larval neuron,ventral nerve cord commissure,commissure,longitudinal connective,mesothoracic dorsal triscolopidial chordotonal organ dch3,metathoracic dorsal triscolopidial chordotonal organ dch3,dMP2 neuron,embryonic/larval central nervous system,presumptive embryonic/larval central nervous system,midline crossing tract,ventral nerve cord commissure & larval brain | somatic clone,tritocerebral commissure,ventral anastomosis 0,ventral anastomosis 1,ventral anastomosis 2,ventral nerve cord,anterior commissure,posterior commissure,intersegmental nerve,midline glial cell,abdominal segmental nerve,axon | cell autonomous,neuroblast NB3-1,cell autonomous,neuroblast NB5-6,RP3 motor neuron,RP2 motor neuron,aCC neuron,V neuron,connective,ganglionic branch primordium,embryonic ventral nervous system,giant fiber neuron,antennal lobe glomerulus,antennal commissure,chordotonal organ & embryo & nerve terminal12.1,pCC neuron,motor neuron,dendriteeve.CQ2,longitudinal connective | embryonic stage,somatic clone,neuropil,dendrite | somatic cloneVGlut-OK371,longitudinal connective | embryonic stage 16,midline crossing tract | embryonic stage 16,dorsal branch | third instar larval stage" DRSC11336 I -0.559750369 1.500904487 0.856985588 0.671218101 -0.458750341 -1.099834365 FBgn0011739 wts warts http://flybase.org/reports/FBgn0011739 FBgn0013549 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VY77 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 protein binding ; GO:0005515 | inferred from physical interaction with yki protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95RA8 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" "mitotic nuclear division ; GO:0007067 | inferred from electronic annotation with InterPro:IPR028741 hippo signaling ; GO:0035329 | inferred from biological aspect of ancestor with PANTHER:PTN001219863 regulation of dendrite morphogenesis ; GO:0048814 | inferred from genetic interaction with sav positive regulation of apoptotic process ; GO:0043065 | inferred from genetic interaction with sav negative regulation of cell proliferation ; GO:0008285 | traceable author statement negative regulation of glial cell proliferation ; GO:0060253 | inferred from mutant phenotype R8 cell fate specification ; GO:0045464 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype negative regulation of organ growth ; GO:0046621 | traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay regulation of imaginal disc growth ; GO:0045570 | traceable author statement regulation of cell proliferation ; GO:0042127 | traceable author statement cell fate specification ; GO:0001708 | inferred from mutant phenotype imaginal disc growth ; GO:0007446 | inferred from mutant phenotype stem cell proliferation ; GO:0072089 | inferred from direct assay intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ; GO:0042771 | inferred from genetic interaction with p53 trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 protein phosphorylation ; GO:0006468 | non-traceable author statement G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from biological aspect of ancestor with PANTHER:PTN001219863 negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype" adherens junction ; GO:0005912 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from physical interaction with Smurf "Wts, wts, Lats/Warts, Warts/Lats, lats, Dlats, Warts, dmLATS, LATS, lts, WTS/LATS, CG12072, warts/lats, Lats, l(3)100Aa, wart, Wts/Lats, wts/lats, warts, MENE (3R)-G, LATS1" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR011989:Armadillo-like helical, IPR028741:Serine/threonine-protein kinase LATS1/ Warts" CG12072 11-Aug-17 DroID_v2017_08 "Drer\lats2, Drer\stk38l, Drer\stk38a, Drer\stk38b, Drer\lats1" "Scer\CBK1, Scer\DBF2, Scer\STE20, Scer\DBF20" "Cele\tlk-1, Cele\sax-1, Cele\wts-1" "Xtro\lats2, Xtro\stk38, Xtro\stk38l" "Mmus\Lats2, Mmus\Lats1, Mmus\Stk38l, Mmus\Stk38" "Hsap\LATS2, Hsap\STK38, Hsap\STK38L, Hsap\LATS1" " embryonic stage -- adult stage , adult stage | male , adult stage | female , embryonic stage | 0-4hr " "lethal,recessive,tumorigenic,neuroanatomy defective,visible,increased cell number,hyperplasia,partially lethal - majority die,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during third instar larval stage,somatic clone,male sterile,female sterile,decreased cell death,progressive,cell migration defective,stress response defective,mitotic cell cycle defective,size defective,neoplasia,partially,viable,body color defective,heat sensitive,increased cell growth" "eye disc,somatic clone,photoreceptor cell R8 of yellow ommatidium,photoreceptor cell R8 of pale ommatidium,supernumerary,rhabdomere R8,dorsal multidendritic neuron ddaC,eye,wing disc,retinal pigment cell,ectopic,ommatidium,pigment cell,head,wing,cell cycle | somatic clone,eye photoreceptor cell,progressive,border follicle cell,dorsal multidendritic neuron ddaC | somatic clone & dendritic tree,inter-ommatidial cell,intestinal stem cell,class IV dendritic arborizing neuron,dendrite,ommatidial precursor cluster,morphogenetic furrow,embryonic/larval central nervous system,pupa,imaginal disc,wing hair,posterior compartment,mesothoracic tergum,eye disc | third instar larval stage,embryonic/larval brain | third instar larval stage,embryonic/larval glial cell | third instar larval stage,terminal tracheal cell,embryonic/larval tracheal system,wing disc posterior compartment" FBgn0034970 yki yorkie http://flybase.org/reports/FBgn0034970 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with ex inferred from physical interaction with wts inferred from physical interaction with hpo transcription factor binding ; GO:0008134 | inferred from physical interaction with sd protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P51140 transcription coactivator activity ; GO:0003713 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P29310 inferred from physical interaction with UniProtKB:P92177 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P30052 transcription coactivator activity ; GO:0003713 | inferred from mutant phenotype "positive regulation of histone H3-K4 trimethylation ; GO:1905437 | inferred from mutant phenotype stem cell proliferation ; GO:0072089 | inferred from direct assay cell proliferation ; GO:0008283 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype hippo signaling ; GO:0035329 | inferred from mutant phenotype regulation of growth ; GO:0040008 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay heart morphogenesis ; GO:0003007 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype positive regulation of glial cell proliferation ; GO:0060252 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype positive regulation of growth ; GO:0045927 | inferred from mutant phenotype morphogenesis of an epithelial sheet ; GO:0002011 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay late endosome ; GO:0005770 | colocalizes_with inferred from direct assay lysosome ; GO:0005764 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "yki, Yki, CG4005, yap, YKI, YAP" IPR001202:WW domain CG4005 11-Aug-17 DroID_v2017_08 "Drer\yap1, Drer\nedd4l, Drer\nedd4a, Drer\hecw1b, Drer\hecw2a, Drer\bag3, Drer\smurf2, Drer\hecw2b, Drer\wwp2, Drer\LOC100334952, Drer\smurf1, Drer\itcha, Drer\wwtr1" "Scer\RSP5, Scer\TOM1" "Cele\sav-1, Cele\yap-1" "Xtro\hecw1, Xtro\smurf1, Xtro\wwp2, Xtro\wwtr1, Xtro\yap1, Xtro\nedd4l, Xtro\nedd4, Xtro\itch, Xtro\bag3" "Mmus\Wwtr1, Mmus\Nedd4l, Mmus\Wwp2, Mmus\Hecw2, Mmus\Wwp1, Mmus\Yap1, Mmus\Hecw1, Mmus\Gas7, Mmus\Smurf2, Mmus\Bag3, Mmus\Smurf1, Mmus\Nedd4, Mmus\Itch" "Hsap\WWP2, Hsap\BAG3, Hsap\WWP1, Hsap\ITCH, Hsap\SMURF2, Hsap\NEDD4, Hsap\HECW2, Hsap\WWTR1, Hsap\HECW1, Hsap\NEDD4L, Hsap\SMURF1, Hsap\GAS7, Hsap\YAP1" "neuroanatomy defective,visible,size defective,increased cell number,somatic clone,mitotic cell cycle defective,hyperplasia,lethal,cell lethalcell lethal,increased cell size,cell shape defective,progressive,decreased cell death,increased cell growth,cell size defective,decreased cell number,cell migration defective,partially,lethal - all die before end of larval stage,some die during larval stage,tumorigenic,neoplasia,lethal - all die before end of pupal stage,some die during pupal stage" "larval outer optic anlage,larval inner optic anlage,eye,wing disc,posterior compartment,eye disc,intestinal stem cell,somatic clone,wing,eye photoreceptor cell,progressive,interommatidial bristle,supernumerary,pigment cell,eye-antennal disc,eye disc posterior to the morphogenetic furrow,epithelial cell,adult cuticle,adherens junctionen-e16E,cell autonomous,cell non-autonomous,interommatidial bristle | somatic cloneFRT.Act5C,border follicle cell,leg,haltere,follicle cell,eye disc | third instar larval stage,embryonic/larval brain | third instar larval stage,ventral nerve cord | third instar larval stage,embryonic/larval optic stalk | third instar larval stage,embryonic/larval glial cell | third instar larval stage,larval optic anlage,eye disc | larval stage,wing pouch,intestinal stem cell of posterior adult midgut epithelium,adult head,mesothoracic tergum,inter-ommatidial cell | pupal stage" DRSC28304 K 0.177098259 0.086929076 -0.360707193 0.149956402 0.866679245 2.651596454 FBgn0034659 CG4021 - http://flybase.org/reports/FBgn0034659 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 RNA binding ; GO:0003723 | inferred from sequence model biological_process ; GO:0008150 | no biological data available nuclear speck ; GO:0016607 | inferred from direct assay "CG4021, cg4021" "IPR004088:K Homology domain, type 1, IPR004087:K Homology domain" CG4021 11-Aug-17 DroID_v2017_08 "Drer\khdrbs3, Drer\khdrbs1b, Drer\qkib, Drer\khdrbs2, Drer\khdrbs1a, Drer\qki2, Drer\qkia" Scer\MSL5 "Cele\asd-2, Cele\K07H8.9, Cele\Y57G11C.36, Cele\gld-1" "Xtro\khdrbs1, Xtro\khdrbs2, Xtro\qki, Xtro\khdrbs3" "Mmus\Khdrbs1, Mmus\Khdrbs3, Mmus\Qk, Mmus\Khdrbs2" "Hsap\QKI, Hsap\KHDRBS3, Hsap\KHDRBS2, Hsap\KHDRBS1" "male fertile,viable" FBgn0032507 CG9377 - http://flybase.org/reports/FBgn0032507 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "c-SPH166, SPH166, CG9377" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG9377 11-Aug-17 DroID_v2017_08 Drer\f7 - Cele\try-1 - Mmus\F9 "Hsap\F9, Hsap\F10" viable FBgn0011225 jar jaguar http://flybase.org/reports/FBgn0011225 "FBgn0004452, FBgn0010074" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR004009 motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR004009 motor activity ; GO:0003774 | non-traceable author statement microtubule binding ; GO:0008017 | inferred from direct assay actin filament binding ; GO:0051015 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with mira protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VJE5 actin binding ; GO:0003779 | non-traceable author statement ATPase activity, coupled ; GO:0042623 | non-traceable author statement microfilament motor activity ; GO:0000146 | non-traceable author statement calmodulin binding ; GO:0005516 | inferred from physical interaction with Cam ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity myosin VI light chain binding ; GO:0070856 | inferred from physical interaction with Acam myosin light chain binding ; GO:0032027 | inferred from physical interaction with Mlc-c actin binding ; GO:0003779 | inferred from mutant phenotype actin binding ; GO:0003779 | inferred from direct assay" "sperm individualization ; GO:0007291 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from expression pattern establishment of mitotic spindle localization ; GO:0040001 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype positive regulation of exocytosis ; GO:0045921 | inferred from mutant phenotype basal protein localization ; GO:0045175 | inferred from mutant phenotype inferred from genetic interaction with l(2)gl regulation of protein localization ; GO:0032880 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from mutant phenotype cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte ; GO:0019749 | inferred from direct assay inferred from mutant phenotype cell-cell junction maintenance ; GO:0045217 | traceable author statement protein localization ; GO:0008104 | inferred from mutant phenotype pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from genetic interaction with shi neuroblast division ; GO:0055057 | inferred from mutant phenotype nucleus organization ; GO:0006997 | inferred from mutant phenotype basal protein localization ; GO:0045175 | traceable author statement nucleus localization ; GO:0051647 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | traceable author statement membrane organization ; GO:0061024 | traceable author statement metamorphosis ; GO:0007552 | inferred from mutant phenotype mitochondrion transport along microtubule ; GO:0047497 | inferred from direct assay spermatid development ; GO:0007286 | inferred from mutant phenotype flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype regulation of actin filament-based process ; GO:0032970 | inferred from mutant phenotype actin filament-based movement ; GO:0030048 | non-traceable author statement pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | traceable author statement morphogenesis of follicular epithelium ; GO:0016333 | inferred from mutant phenotype actin filament-based movement ; GO:0030048 | inferred from direct assay oogenesis ; GO:0048477 | non-traceable author statement regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype imaginal disc morphogenesis ; GO:0007560 | inferred from mutant phenotype regulation of actin filament-based process ; GO:0032970 | inferred from genetic interaction with shi asymmetric neuroblast division ; GO:0055059 | traceable author statement" sperm individualization complex ; GO:0070864 | inferred from direct assay unconventional myosin complex ; GO:0016461 | inferred from direct assay myosin VI complex ; GO:0031476 | inferred from physical interaction with Mlc-c investment cone ; GO:0070865 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay myosin VI complex ; GO:0031476 | inferred from physical interaction with Acam investment cone ; GO:0070865 | colocalizes_with inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay unconventional myosin complex ; GO:0016461 | non-traceable author statement protein complex ; GO:0043234 | inferred from physical interaction with corn filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay germline ring canal ; GO:0045172 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay myosin complex ; GO:0016459 | inferred from sequence or structural similarity endocytic vesicle ; GO:0030139 | inferred from direct assay "jar, MyoVI, Dm 95F, Dm95F, MYOVI, MHC95F, JAG, CG5695, 95F, Mhc95F, 95F MHC, Dro95F, ms(3)06746, jag, M6, myosins VI, Jaguar, Jar, Myo1A, Myosin VI, myo VI, dMyoVI" "IPR000048:IQ motif, EF-hand binding site, IPR001609:Myosin head, motor domain, IPR004009:Myosin, N-terminal, SH3-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR032412:Myosin VI, cargo binding domain" CG5695 11-Aug-17 DroID_v2017_08 "Drer\myo19, Drer\myo6b, Drer\myo6a" "Scer\MYO4, Scer\MYO1" "Cele\hum-8, Cele\spe-15" Xtro\myo6 Mmus\Myo6 Hsap\MYO6 " embryonic stage , adult stage " " larval stage , adult stage , oogenesis stage | stage S9 , oogenesis stage | stage S9-10 , embryonic stage | late , oogenesis stage | stage S10 " " larval brain

, adult head

, adult thorax

, border follicle cell

, follicle cell

, gonad

, adult brain

" "partially lethal - majority die,male sterile,female fertile,embryonic/larval segmentation phenotype,male semi-sterile,recessive,viable,sterile,fertile,lethal,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,small body,visible,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage" "neuroblast & spindle, with jardsRNA.2,neuroblast & spindle, with jardsRNA.1,denticle belt,investment cone, with jar1/Df(3R)crb87-5,spermatid cyst,spermatozoon,spermatid,investment cone,investment conecrb87-5),seminal vesicle,investment conecrb87-5), with jarDel-N-Gtail.Hsp83.TAvicGFP,investment conecrb87-5), with jarmRRL.Hsp83.TAvicGFP,investment conecrb87-5), with jarmWKA.Hsp83.TAvicGFP,investment conecrb87-5), with jarmLWY.Hsp83.TAvicGFP,investment conecrb87-5), with jarHNPMD.Hsp83.TAvicGFP,dorsal closure embryo,embryonic leading edge cell,amnioserosa & actin filament,embryonic epidermis,lateral,posterior spiracle primordium,neuroblast & spindlemat.‘±Tub67C.THsimVP16,dorsal denticle,third instar larval cuticle,wing,leg,follicle cell,egg chamber,nurse cell & nucleusc532,follicle cell & nucleusc532,centripetally migrating follicle cell,border follicle cell,filopodium & border follicle cellslbo.2.6,trichogen cell,tormogen cell,male genitalia" FBgn0010583 dock dreadlocks http://flybase.org/reports/FBgn0010583 FBgn0041141 protein_coding_gene cell adhesion molecule binding ; GO:0050839 | inferred from physical interaction with rst inferred from physical interaction with sns inferred from physical interaction with kirre inferred from physical interaction with hbs insulin receptor binding ; GO:0005158 | inferred from physical interaction with InR SH3/SH2 adaptor activity ; GO:0005070 | traceable author statement protein kinase binding ; GO:0019901 | inferred from physical interaction with Pak SH3/SH2 adaptor activity ; GO:0005070 | inferred from sequence or structural similarity with HGNC:7664 protein binding ; GO:0005515 | inferred from physical interaction with ckn "axon guidance ; GO:0007411 | traceable author statement insulin receptor signaling pathway ; GO:0008286 | inferred from physical interaction with InR negative regulation of insulin receptor signaling pathway ; GO:0046627 | inferred from genetic interaction with Ptp61F, InR axonogenesis ; GO:0007409 | traceable author statement axon guidance ; GO:0007411 | inferred from genetic interaction with Dscam1 axon guidance ; GO:0007411 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from genetic interaction with sns inferred from genetic interaction with kirre inferred from genetic interaction with hbs" cytoplasm ; GO:0005737 | non-traceable author statement "dock, Dock, Nck, Dm0447, doc, dck, l(2)04723, CG3727, DOCK" "IPR000980:SH2 domain, IPR001452:SH3 domain, IPR017304:Cytoplasmic protein NCK" CG3727 11-Aug-17 DroID_v2017_08 "Drer\nck2b, Drer\nck2a, Drer\nck1b, Drer\nck1a" - Cele\nck-1 "Xtro\nck2, Xtro\nck1" "Mmus\Nck2, Mmus\Nck1" "Hsap\NCK2, Hsap\NCK1" " embryonic stage | stage 14 , embryonic stage&&pupal stage&&adult stage " " embryonic brain

, ventral nerve cord

" larval stage | third instar " eye-antennal disc

, lamina neuropil

, neuron

, medulla neuropil

" "lethal,recessive,maternal effect,neuroanatomy defective,lethal - all die before end of pupal stage,uncoordinated,some die during pupal stage,somatic clone,cell non-autonomous,wild-type,visible,viable" "Bolwig nerve,longitudinal connective,embryonic/larval somatic muscle,RP3 neuron & synapse,maternal effect,photoreceptor cell & axon,ventral nerve cord commissure,VUM neuron,lamina neuropil,lamina anlage,medulla anlage,embryonic/larval optic lobe,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina,medulla,eye photoreceptor cell & growth cone,photoreceptor & axon,photoreceptor cell R7 & axon,photoreceptor & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,somatic clone,pCC neuron,MP1 neuron,neuron,photoreceptor cell,lamina plexus,embryonic/larval optic stalk,larval outer optic anlage,larval inner optic anlage,lobula,antennal lobe,antennal lobe & neuropil,antennal lobe glomerulus DM2,antennal lobe glomerulus DM3,cell non-autonomous,adult antennal nerve,antennal lobe glomerulus,ectopic,glial cell & antennal lobe,neuron & antennal lobe,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell & axon | somatic clone,RP3 motor neuron,neuromuscular junction | embryonic stage,eye" DRSC00812 I -0.020510833 -1.633869854 -0.184981699 -0.111917552 0.223467851 -0.688179154 FBgn0010303 hep hemipterous http://flybase.org/reports/FBgn0010303 "FBgn0013490, FBgn0029076, FBgn0030446, FBgn0040188" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 JUN kinase kinase activity ; GO:0008545 | inferred from sequence or structural similarity receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement JUN kinase kinase activity ; GO:0008545 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Cka protein kinase binding ; GO:0019901 | inferred from physical interaction with UniProtKB:Q9W0K0 MAP kinase kinase activity ; GO:0004708 | traceable author statement receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 MAP-kinase scaffold activity ; GO:0005078 | inferred from direct assay protein kinase activity ; GO:0004672 | inferred from direct assay" "ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype melanization defense response ; GO:0035006 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype inferred from genetic interaction with Rab30 response to heat ; GO:0009408 | inferred from mutant phenotype positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype imaginal disc fusion ; GO:0046528 | inferred from mutant phenotype JNK cascade ; GO:0007254 | traceable author statement protein phosphorylation ; GO:0006468 | traceable author statement cellular response to arsenic-containing substance ; GO:0071243 | inferred from mutant phenotype cellular response to cadmium ion ; GO:0071276 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype filopodium assembly ; GO:0046847 | inferred from mutant phenotype basement membrane disassembly ; GO:0034769 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | traceable author statement imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype micropyle formation ; GO:0046844 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | non-traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype positive regulation of JUN kinase activity ; GO:0043507 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr protein phosphorylation ; GO:0006468 | non-traceable author statement engulfment of apoptotic cell ; GO:0043652 | inferred from mutant phenotype chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype carbohydrate homeostasis ; GO:0033500 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement axon guidance ; GO:0007411 | inferred from direct assay imaginal disc fusion, thorax closure ; GO:0046529 | inferred from genetic interaction with slpr dorsal closure ; GO:0007391 | non-traceable author statement dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from genetic interaction with Mkk4 lamellipodium assembly ; GO:0030032 | inferred from mutant phenotype MAPK cascade ; GO:0000165 | non-traceable author statement" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 axon ; GO:0030424 | inferred from direct assay "hep, Hep, HEP/MKK7, DJNKK, HEP, JNKK, MKK7, DHEP/MKK7, CG2190, CG4353, DMKK7, hp, l(1)G0107, l(1)G0208, l(1)7P1, hem, dMKK7, hrp, MAPKK, dJNKK, D-MKK7, Hep/Mkk7, Mkk7, hep/JNKK, MAP2K7" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG4353 11-Aug-17 DroID_v2017_08 "Drer\map2k7, Drer\map2k4b, Drer\map2k4a" "Scer\STE7, Scer\MKK2, Scer\PBS2" "Cele\sek-4, Cele\jkk-1, Cele\sek-5, Cele\mek-1, Cele\mkk-4, Cele\sek-3" "Xtro\map2k7, Xtro\map2k4, Xtro\abl1, Xtro\map2k6" "Mmus\Map2k3, Mmus\Ulk1, Mmus\Tgfbr3l, Mmus\Map2k7, Mmus\Map2k4, Mmus\Map2k6" "Hsap\MAP2K6, Hsap\MAP2K7, Hsap\MAP2K3, Hsap\MAP2K4" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "lethal,recessive,visible,chemical sensitive,lethal - all die before end of embryonic stage,viable,female,rescuable maternal effect,neuroanatomy defective,stress response defective,some die during embryonic stage,maternal effect,dominant,increased cell death,heat sensitive,lethal - all die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,male,wild-type,somatic clone,wound healing defective,mitotic cell cycle defective,small body,heat stress response defective,cell lethal,partially,cell shape defective,planar polarity defective,size defective,hyperplasia,temperature conditional,tumorigenic,partially lethal - majority live,cell death defective,chemical resistant,RU486 conditional,long lived,short lived" "adult thorax,chaeta,cuticle,dorsal,rescuable maternal effect,embryonic leading edge cell,embryonic dorsal epidermis,eye,wing,thorax,leg,mesothoracic tergum,wing disc,dorsal appendage,embryonic/first instar larval cuticle,embryonic epidermis,dorsal closure embryo,amnioserosa,embryonic leading edge cell & actin filament,adult head,adult mesothoracic segment,macrochaeta,maternal effect,axon & dorsal cluster neuron,maxillary palpus,female terminalia,germline clone,eye disc,imaginal disc,Kenyon cell,somatic clone,axon | somatic clone,eye-antennal disc,ventral thoracic disc,interommatidial bristle,pigment cell,micropyle,egg chamber,anterior,embryonic leading edge cell & filopodium,dorsal mesothoracic disc & cytoskeleton,cuticle & thorax,cuticle & abdomen,cephalopharyngeal skeleton,cuticle & thorax | germ-line clone,cuticle & abdomen | germ-line clone,peripodial epithelium & dorsal mesothoracic disc & prepupa,peripodial stalk & dorsal mesothoracic disc & prepupa,follicle cell,basement membrane | pupal stage,neuron,lamina,eye photoreceptor cell,embryonic maxillary segment,ommatidial precursor cluster,autolysosome | third instar larval stage,autophagic vacuole | third instar larval stage,embryonic/larval gut | third instar larval stage,embryonic/larval fat body | third instar larval stage,adult gut,temperature conditional,lamellocyte,melanotic mass,ventral adult lateral neuron & axonP2.4.Pdf,axon & dorsal cluster neuronato.3.6,wing vein,wing margin,wing vein L5,neuroblast | larval stage,scutellum,adult thorax & macrochaetapnr-MD237,ommatidium,genital disc,ventral furrow,heat sensitive" DRSC19839 K 0.835328143 1.228856735 0.385846125 0.591701195 -0.614963357 -1.538616774 FBgn0000163 baz bazooka http://flybase.org/reports/FBgn0000163 "FBgn0040145, FBgn0042632" protein_coding_gene phosphatidic acid binding ; GO:0070300 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Traf4 phosphatidylinositol binding ; GO:0035091 | inferred from direct assay "border follicle cell delamination=0030709 |... apical protein localization=0045176 | .. apical/basal cell polarity=0035089 |... branching .. open tracheal system development=0060446 |... establishment or maintenance of polarity of embryonic epithelium=0016332 | establishment or maintenance of neuroblast polarity=0045196 | asymmetric protein localization=0008105 | morphogenesis of an epithelium=0002009 | basal protein localization=0045175 | Malpighian tubule development=0072002 |... zonula adherens assembly=0045186 | mitotic cytokinesis=0000281 |... .. planar cell polarity pathway .. axis elongation=2000040 |... establishment or maintenance of epithelial cell apical/basal polarity=0045197 | border follicle cell migration=0007298 |... .. mitotic spindle localization=0040001 | asymmetric neuroblast division=0055059 |... asymmetric neuroblast division=0055059 |... with pins zonula adherens assembly=0045186 | synapse assembly=0007416 |... zonula adherens assembly=0045186 |... cell-cell adhesion .. .. planar polarity=0090250 |... .. .. planar polarity=0090175 |... with dgo asymmetric cell division=0008356 | germ-band extension=0007377 | germarium-derived oocyte fate determination=0007294 |... oocyte axis specification=0007309 | ovarian follicle cell-cell adhesion=0007299 |... establishment or maintenance of epithelial cell apical/basal polarity=0045197 | asymmetric protein localization .. cell fate determination=0045167 |... morphogenesis of a polarized epithelium=0001738 | oocyte microtubule cytoskeleton organization=0016325 |... germ-band extension=0007377 |... photoreceptor cell morphogenesis=0008594 |... cuticle development=0042335 |... with A1Z9X0,Q9VX75,X2JCB3,X2JFU8 inferred from with P10040,Q9VX75,X2JCB3,X2JFU8 inferred from with P48148,Q9VX75,X2JCB3,X2JFU8 inferred from with Q24298,Q9VX75,X2JCB3,X2JFU8 inferred from with Q95U75,Q9VX75,X2JCB3,X2JFU8 inferred from with Q960Y8,Q9VX75,X2JCB3,X2JFU8 inferred from with Q9BN17,Q9VX75,X2JCB3,X2JFU8 inferred from with Q9VC45,Q9VX75,X2JCB3,X2JFU8 inferred from with Q9VEH0,Q9VX75,X2JCB3,X2JFU8 inferred from with Q9VEJ4,Q9VX75,X2JCB3,X2JFU8 inferred from with A1Z9X0,Q0KHR3,X2JCB3,X2JFU8 inferred from with P10040,Q0KHR3,X2JCB3,X2JFU8 inferred from with P48148,Q0KHR3,X2JCB3,X2JFU8 inferred from with Q0KHR3,Q24298,X2JCB3,X2JFU8 inferred from with Q0KHR3,Q95U75,X2JCB3,X2JFU8 inferred from with Q0KHR3,Q960Y8,X2JCB3,X2JFU8 inferred from with Q0KHR3,Q9BN17,X2JCB3,X2JFU8 inferred from with Q0KHR3,Q9VC45,X2JCB3,X2JFU8 inferred from with Q0KHR3,Q9VEH0,X2JCB3,X2JFU8 inferred from with Q0KHR3,Q9VEJ4,X2JCB3,X2JFU8 inferred from with A1Z9X0,Q0KHR3,Q9VX75,X2JFU8 inferred from with P10040,Q0KHR3,Q9VX75,X2JFU8 inferred from with P48148,Q0KHR3,Q9VX75,X2JFU8 inferred from with Q0KHR3,Q24298,Q9VX75,X2JFU8 inferred from with Q0KHR3,Q95U75,Q9VX75,X2JFU8 inferred from with Q0KHR3,Q960Y8,Q9VX75,X2JFU8 inferred from with Q0KHR3,Q9BN17,Q9VX75,X2JFU8 inferred from with Q0KHR3,Q9VC45,Q9VX75,X2JFU8 inferred from with Q0KHR3,Q9VEH0,Q9VX75,X2JFU8 inferred from with Q0KHR3,Q9VEJ4,Q9VX75,X2JFU8 inferred from with A1Z9X0,Q0KHR3,Q9VX75,X2JCB3 inferred from with P10040,Q0KHR3,Q9VX75,X2JCB3 inferred from with P48148,Q0KHR3,Q9VX75,X2JCB3 inferred from with Q0KHR3,Q24298,Q9VX75,X2JCB3 inferred from with Q0KHR3,Q95U75,Q9VX75,X2JCB3 inferred from with Q0KHR3,Q960Y8,Q9VX75,X2JCB3 inferred from with Q0KHR3,Q9BN17,Q9VX75,X2JCB3 inferred from with Q0KHR3,Q9VC45,Q9VX75,X2JCB3 inferred from with Q0KHR3,Q9VEH0,Q9VX75,X2JCB3 inferred from with Q0KHR3,Q9VEJ4,Q9VX75,X2JCB3 cell-cell junction assembly=0007043 | oocyte anterior/posterior axis specification=0007314 |... establishment or maintenance of cell polarity=0007163 | establishment or maintenance of epithelial cell apical/basal polarity=0045197 |... negative .. filopodium assembly=0051490 |... mutant phenotype" apical cortex ; GO:0045179 | non-traceable author statement zonula adherens ; GO:0005915 | inferred from direct assay subapical complex ; GO:0035003 | traceable author statement apical cortex ; GO:0045179 | traceable author statement adherens junction ; GO:0005912 | inferred from direct assay apical junction complex ; GO:0043296 | inferred from direct assay apical plasma membrane ; GO:0016324 | non-traceable author statement apical part of cell ; GO:0045177 | non-traceable author statement cell cortex ; GO:0005938 | traceable author statement spot adherens junction ; GO:0005914 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay apical plasma membrane ; GO:0016324 | traceable author statement "Baz, baz, Par-3, par-3, PAR3, Par3, dPar-3, l(1)G0484, D-Par3, CG5055, Bazooka, bazooka, Baz/Par-3, PAR-3, BAZ, D-par3, Baz/Par3, par3" "IPR001478:PDZ domain, IPR021922:Domain of unknown function DUF3534" CG5055 11-Aug-17 DroID_v2017_08 "Drer\pard3ba, Drer\pard3, Drer\LOC101882925, Drer\pard3bb" - "Cele\par-3, Cele\magi-1" "Xtro\pard3, Xtro\pard3b" "Mmus\Pard3b, Mmus\Pard3" "Hsap\PARD3B, Hsap\PARD3" embryonic stage " epithelial cell | apical

, neuroblast | apical

" " adult stage | female ,, embryonic stage " " germline cell

, stage S3 oocyte

anterior , neuroblast | apical

, stage S5 oocyte

anterior , epithelial cell | apical

" "female sterile,germline clone,lethal,recessive,increased cell death,viable,fertile,cell migration defective,planar polarity defective,cell polarity defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,cell shape defective,somatic clone,neurophysiology defective,neuroanatomy defective,partially lethal - majority die,visible" "photoreceptor cell & eye | somatic clone,embryonic neuroblast & spindle | germ-line clone,dorsal appendage,germline clone,maternal effect,oocyte nucleus,microtubule | germline clone,embryonic epidermis,embryonic/first instar larval cuticle,border follicle cell,embryonic abdominal segment,microtubule,embryo,terminal tracheal cell,somatic clone,follicle cell,oocyte,nurse cell,egg chamber,nurse cell fusome,epithelial cell,oocyte & centrosome | germ-line clone,oocyte & microtubule | germ-line clone,embryonic epidermis & spindle,embryonic ganglion mother cell,presumptive embryonic/larval central nervous system,embryonic leading edge cell,zonula adherens,adherens junction,neuroblast,dorsal,ventral,bouton,eye photoreceptor cell & eye disc & pupa | somatic clone,eye photoreceptor cell & eye disc & pupa | somatic clone | cell non-autonomous,eye,embryonic head,spot adherens junction,ommatidium,embryonic Malpighian tubule,late extended germ band embryo,presumptive embryonic/larval nervous system,embryonic/larval cuticle,ectopic,zonula adherens | somatic clone,germ band,egg,microtubuleunspecified,macrochaeta,trichogen cell,supernumerary,embryonic/larval neuromuscular junction,NMJ bouton" FBgn0020278 loco locomotion defects http://flybase.org/reports/FBgn0020278 FBgn0038997 protein_coding_gene "signal transducer activity, downstream of receptor ; GO:0005057 | inferred from electronic annotation with InterPro:IPR003116 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P20353 G-protein alpha-subunit binding ; GO:0001965 | inferred from physical interaction with Gαi GTPase activator activity ; GO:0005096 | inferred from direct assay GDP-dissociation inhibitor activity ; GO:0005092 | inferred from direct assay" "regulation of asymmetric cell division ; GO:0009786 | inferred from direct assay response to heat ; GO:0009408 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype axon ensheathment in central nervous system ; GO:0032291 | inferred from mutant phenotype dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype establishment of endothelial blood-brain barrier ; GO:0014045 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype embryonic axis specification ; GO:0000578 | inferred from mutant phenotype glial cell differentiation ; GO:0010001 | inferred from mutant phenotype regulation of G-protein coupled receptor protein signaling pathway ; GO:0008277 | inferred from genetic interaction with pins establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype heart process ; GO:0003015 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "loco, dLoco, CG17229, CG5248, Loco, LOCO" "IPR001478:PDZ domain, IPR003109:GoLoco motif, IPR003116:Raf-like Ras-binding, IPR006020:PTB/PI domain, IPR016137:RGS domain, IPR024066:RGS, subdomain 1, IPR034484:Regulator of G-protein signalling Loco, IPR029071:Ubiquitin-related domain, IPR011993:PH domain-like" CG5248 11-Aug-17 DroID_v2017_08 "Drer\rgs11, Drer\grid2ipb, Drer\rgs20, Drer\dlg5a, Drer\rgs1, Drer\grip1, Drer\lnx1, Drer\pdzd7b, Drer\axin1, Drer\pard3bb, Drer\axin2, Drer\grip2b, Drer\rgs16, Drer\inadl, Drer\rgs5b, Drer\rgs5a, Drer\si:ch211-152p11.4, Drer\rgs13, Drer\rgs14b, Drer\si:ch211-117l17.6, Drer\si:ch211-117l17.5, Drer\rgs12b, Drer\grid2ipa, Drer\si:ch211-196h16.12, Drer\rgs19, Drer\rgs12a, Drer\il16, Drer\rgs8, Drer\slc9a3r1, Drer\rgs17, Drer\si:dkey-92i15.4, Drer\rgs9b, Drer\rgs2, Drer\rgs3a, Drer\rgs4, Drer\rgs18, Drer\rgs6, Drer\rgs14a" "Scer\RGS2, Scer\SST2" "Cele\rgs-1, Cele\rgs-7, Cele\rgs-2, Cele\rgs-6" "Xtro\rgs2, Xtro\dlg5, Xtro\rgs18, Xtro\rgs19, Xtro\cep112, Xtro\grip2, Xtro\rgs17, Xtro\rgs1, Xtro\rgs3, Xtro\grip1, Xtro\rgs20, Xtro\rgs6, Xtro\rgs16, Xtro\rgs4, Xtro\axin1, Xtro\xarp, Xtro\lnx1, Xtro\rgs10, Xtro\rgs5, Xtro\grid2ip" "Mmus\Rgs17, Mmus\Axin2, Mmus\Patj, Mmus\Rgs8, Mmus\Rgs6, Mmus\Rgs1, Mmus\Axin1, Mmus\Grasp, Mmus\Rgs3, Mmus\Grid2ip, Mmus\Rgs9, Mmus\Rgs4, Mmus\Rgs13, Mmus\Rgs11, Mmus\Lnx1, Mmus\Grip2, Mmus\Pdzph1, Mmus\Pdzd11, Mmus\Mpdz, Mmus\Rgs12, Mmus\Rgs21, Mmus\Rgs20, Mmus\Rgs5, Mmus\Rgs7, Mmus\Rgs10, Mmus\Rgs16, Mmus\Dlg5, Mmus\Pdzd2, Mmus\Il16, Mmus\Grip1, Mmus\Rgs14, Mmus\Rgs2, Mmus\Rgs19, Mmus\Rgs18, Mmus\Ush1c" "Hsap\PDZD2, Hsap\GRASP, Hsap\RGS17, Hsap\RGS18, Hsap\LNX1, Hsap\RGS7, Hsap\PATJ, Hsap\RGS10, Hsap\RGS19, Hsap\AXIN1, Hsap\FRMPD2, Hsap\GRIP1, Hsap\RGS20, Hsap\RGS12, Hsap\RGS9, Hsap\RGS3, Hsap\RGS16, Hsap\IL16, Hsap\RGS5, Hsap\PARD3B, Hsap\RGS21, Hsap\RGS14, Hsap\RGS13, Hsap\RGS4, Hsap\RGS8, Hsap\DLG5, Hsap\GRID2IP, Hsap\MPDZ, Hsap\RGS6, Hsap\AXIN2, Hsap\RGS2, Hsap\RGS11, Hsap\USH1C, Hsap\RGS1" " embryonic stage | stage >=12 , embryonic stage , embryonic stage | stage 16 " " glial cell

, embryonic peripheral nervous system

, lateral ectoderm | dorsal

, lateral ectoderm | restricted

, embryonic/larval tracheal system

" "immune response defective,viable,fertile,male semi-sterile,neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,behavior defective,mitotic cell cycle defective,locomotor behavior defective,paralytic,visible" "hemocyte,testis,male accessory gland,anterior ejaculatory duct,axon | embryonic stage,embryonic/larval glial cell,longitudinal connective,lateral cord surface glia & nucleus,lateral cord surface glia & cell cortex & cortical cytoskeleton,lateral cord surface glia & septate junction,egg,ventral,dorsal appendage,neuroblast,spindle & mitotic domain 9,glial cell,subperineurial glial cell,yolk,embryonic foregut,embryonic/larval midgut primordium,embryonic/first instar larval cuticle,embryonic head,dorsal,tormogen cell" FBgn0011202 dia diaphanous http://flybase.org/reports/FBgn0011202 FBgn0022100 protein_coding_gene "actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR010472, InterPro:IPR010473 protein binding ; GO:0005515 | inferred from physical interaction with chic inferred from physical interaction with Apc2 inferred from physical interaction with Eb1 protein binding ; GO:0005515 | inferred from physical interaction with Cip4 Rho GTPase binding ; GO:0017048 | inferred from mutant phenotype phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from mutant phenotype actin binding ; GO:0003779 | inferred from sequence or structural similarity" "actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype regulation of filopodium assembly ; GO:0051489 | inferred from mutant phenotype maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype protein localization ; GO:0008104 | non-traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype apical constriction ; GO:0003383 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype cellularization ; GO:0007349 | traceable author statement positive regulation of actin filament polymerization ; GO:0030838 | inferred from direct assay spermatogenesis ; GO:0007283 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | non-traceable author statement cellularization ; GO:0007349 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from mutant phenotype positive regulation of wound healing ; GO:0090303 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype membrane tubulation ; GO:0097320 | inferred from mutant phenotype actin nucleation ; GO:0045010 | inferred from direct assay mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype" adherens junction ; GO:0005912 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay actin filament ; GO:0005884 | colocalizes_with inferred from direct assay apical plasma membrane ; GO:0016324 | colocalizes_with inferred from direct assay vesicle membrane ; GO:0012506 | inferred from direct assay cytoneme ; GO:0035230 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Apc2 cytoplasm ; GO:0005737 | inferred from direct assay "dia, Dia, 38E.16, CG1768, l(2)k07135, ms(2)04138, DIA, Dias" "IPR010465:DRF autoregulatory, IPR010472:Formin, FH3 domain, IPR014767:Diaphanous autoregulatory (DAD) domain, IPR014768:Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425:Formin, FH2 domain, IPR011989:Armadillo-like helical, IPR027658:Formin, protein diaphanous, IPR010473:Formin, GTPase-binding domain, IPR016024:Armadillo-type fold" CG1768 11-Aug-17 DroID_v2017_08 "Drer\fhdc4, Drer\fmnl2a, Drer\diaph3, Drer\inf2, Drer\grid2ipb, Drer\grid2ipa, Drer\diaph2, Drer\daam1b" "Scer\BNI1, Scer\BNR1" "Cele\frl-1, Cele\daam-1, Cele\cyk-1" "Xtro\fmnl1, Xtro\inf2, Xtro\diaph2, Xtro\diaph1" "Mmus\Inf2, Mmus\Fmnl3, Mmus\Diaph2, Mmus\Fmnl2, Mmus\Fmnl1, Mmus\Diaph1, Mmus\Grid2ip, Mmus\Daam1, Mmus\Diaph3, Mmus\Daam2" "Hsap\DIAPH2, Hsap\DAAM2, Hsap\DIAPH1, Hsap\GRID2IP, Hsap\FMNL1, Hsap\FMNL3, Hsap\FMNL2, Hsap\INF2, Hsap\DIAPH3, Hsap\DAAM1" " adult stage | female , adult stage | male " "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,non-rescuable maternal effect,cytokinesis defective,auditory perception defective,dominant,neurophysiology defective,somatic clone,wound healing defective,viable,fertile,male sterile,female sterile,wild-type,meiotic cell cycle defective,male,mitotic cell cycle defective,maternal effect,cell shape defective,neuroanatomy defective,partially lethal - majority die,visible,immune response defective" "contractile ring & meiotic cell cycle | male,spindle & meiotic cell cycle | male,imaginal disc,larval central nervous system & neuroblast,actin filament & embryonic/larval tracheal systembtl.PS,filopodium | ectopicen-e16E,epidermal cell,embryonic leading edge cell,furrow canal,germline clone,cycle 11 embryo,cytoskeleton | embryonic stage | germline clone,nucleus | embryonic stage | germline clone,pole cell,gastrula embryo,dorsal closure embryo,embryonic head,denticle belt,embryonic/first instar larval cuticle,actin filament | embryonic stage | germline clone,microtubule | embryonic stage | germline clone,centrosome | embryonic stage | germline clone,pole bud,blastoderm embryo,ventral furrow,non-rescuable maternal effect,actin filament & embryonic/larval tracheal system,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,morphogenetic furrow,somatic clone,epithelium,follicle cell,egg chamber,filopodium,lamellipodium,tormogen cell,bract,organism | dorsal closure stage | maternal effect,amnioserosa,maternal effect,filopodiumen-e16E,lamellipodiumen-e16E,testis,spermatocyte,spermatid,Nebenkern,cyst cell,spermatid & nucleus | supernumerary,spermatid & nucleus | supernumeraryTW84),spindle & meiotic cell cycle | maleTW84),contractile ring & meiotic cell cycle | maleTW84),eye,ectoderm,border follicle cell,tracheal fusion cell,embryonic/larval dorsal trunk,embryonic epidermis,organism | dorsal closure stagec381,epithelial cell,presumptive embryonic/larval central nervous system,commissure,connective,air sac primordium | third instar larval stage,S2 cell-line & spindle microtubule,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,wing" DRSC03519 K 0.67371844 -0.02539349 0.114864457 -0.298054878 -1.62014316 0.014326413 FBgn0011592 fra frazzled http://flybase.org/reports/FBgn0011592 - protein_coding_gene netrin receptor activity ; GO:0005042 | traceable author statement salivary gland boundary specification ; GO:0007432 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype axon guidance ; GO:0007411 | non-traceable author statement regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype axon guidance ; GO:0007411 | traceable author statement axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with comm dendrite morphogenesis ; GO:0048813 | traceable author statement glial cell migration ; GO:0008347 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with robo1 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010560 plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:2701 axon ; GO:0030424 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay perivitelline space ; GO:0098595 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay "CT24981, CG8581, fra, Fra, frazzled, DCC" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR010560:Neogenin, C-terminal, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG8581 11-Aug-17 DroID_v2017_08 "Drer\igfn1.1, Drer\fndc1, Drer\igfn1.3, Drer\dcc, Drer\prtgb, Drer\neo1a, Drer\si:ch211-57n23.4, Drer\igdcc3, Drer\igfn1.4, Drer\igfn1.2, Drer\neo1, Drer\igdcc4" Scer\YML002W "Cele\unc-40, Cele\npr-26" "Xtro\igdcc4, Xtro\neo1" "Mmus\Neo1, Mmus\Fndc1, Mmus\Dcc, Mmus\Prtg, Mmus\Igdcc3, Mmus\Igdcc4" "Hsap\DCC, Hsap\PRTG, Hsap\IGDCC4, Hsap\FNDC1, Hsap\NEO1, Hsap\IGDCC3" embryonic stage " embryonic central nervous system

, embryonic/larval digestive system

" " embryonic stage | late , embryonic stage | stage >=13 , embryonic stage | stage >=12 , embryonic stage | stage 13-17 " " intersegmental nerve

, epidermis

, longitudinal connective

, ventral nerve cord commissure

, segmental nerve

, embryonic/larval midgut

, neuron

, motor nerve

" "behavior defective,neuroanatomy defective,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,viable,female sterile,female fertile" "ventral nerve cord commissure | embryonic stage,EW neuron,EG neuron,presumptive embryonic/larval central nervous system,ventral nerve cord commissure,pCC neuron & axon,intersegmental nerve,longitudinal connective,SP1 neuron,commissure,anterior commissure,posterior commissure,presumptive embryonic salivary gland,dMP2 neuron,fascicle,Bolwig nerve,motor neuron,dendrite,interface glial cell,class IV dendritic arborizing neuron,commissure & embryo & axon,RP3 motor neuron,lamina,optic lobe,somatic clone,photoreceptor cell R8 stalk,neuropil,dendrite | somatic clone,dendrite | somatic cloneVGlut-OK371" FBgn0004657 mys myospheroid http://flybase.org/reports/FBgn0004657 "FBgn0001448, FBgn0001811, FBgn0002992, FBgn0020759, FBgn0025177, FBgn0027260, FBgn0028333, FBgn0029991" protein_coding_gene extracellular matrix protein binding ; GO:1990430 | contributes_to inferred from physical interaction with Tig protein binding ; GO:0005515 | inferred from physical interaction with rhea protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with scb protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with if inferred from physical interaction with mew receptor activity ; GO:0004872 | traceable author statement cell adhesion molecule binding ; GO:0050839 | traceable author statement "tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement cell adhesion mediated by integrin ; GO:0033627 | inferred from direct assay calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype midgut development ; GO:0007494 | traceable author statement muscle attachment ; GO:0016203 | inferred from mutant phenotype substrate adhesion-dependent cell spreading ; GO:0034446 | inferred from direct assay border follicle cell migration ; GO:0007298 | inferred from mutant phenotype pericardium morphogenesis ; GO:0003344 | inferred from mutant phenotype substrate-dependent cell migration, cell extension ; GO:0006930 | inferred from genetic interaction with PDZ-GEF sarcomere organization ; GO:0045214 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from genetic interaction with Rap1 inferred from genetic interaction with PDZ-GEF dorsal closure ; GO:0007391 | traceable author statement cell-substrate adhesion ; GO:0031589 | inferred from mutant phenotype maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype larval heart development ; GO:0007508 | inferred from mutant phenotype central nervous system morphogenesis ; GO:0021551 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype negative regulation of cell migration ; GO:0030336 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement cell adhesion ; GO:0007155 | inferred from mutant phenotype dorsal trunk growth, open tracheal system ; GO:0035001 | inferred from mutant phenotype regulation of stress fiber assembly ; GO:0051492 | inferred from mutant phenotype cell migration ; GO:0016477 | traceable author statement apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | non-traceable author statement germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype salivary gland development ; GO:0007431 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype calcium-dependent cell-matrix adhesion ; GO:0016340 | inferred from sequence or structural similarity dorsal closure ; GO:0007391 | inferred from mutant phenotype imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype cell-matrix adhesion ; GO:0007160 | traceable author statement muscle attachment ; GO:0016203 | traceable author statement germ-band extension ; GO:0007377 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype" muscle tendon junction ; GO:0005927 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay integrin complex ; GO:0008305 | non-traceable author statement costamere ; GO:0043034 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integrin complex ; GO:0008305 | inferred from physical interaction with scb plasma membrane ; GO:0005886 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from sequence or structural similarity integrin complex ; GO:0008305 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from direct assay integrin complex ; GO:0008305 | inferred from sequence or structural similarity basal plasma membrane ; GO:0009925 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay cell leading edge ; GO:0031252 | inferred from direct assay "betaPS1, mys, betaPS, PS, Mys, l(1)7Db, integrin beta[[PS]], CG1560, betamys, beta[[PS]]-integrin, MAb6G11, CT40473, olfC, BetaPS, b[[PS]], beta[[PS]], beta-PS, bPS, l(1)968, beta[[P]]S, l(1)mys, PSbeta, nj42, l(1)93p, EM28, l(1)G0233, l(1)G0281, l(1)EM28, l(1)DA551, l(1)7Dn, PS[[beta]], beta[[mys]], betaPS Int, beta integrin, betaInt, betaPS integrin, beta-int, beta-Int, beta1, BetaPS-Int, betaPS-integrin, beta-integrin, ItgbPS" "IPR002035:von Willebrand factor, type A, IPR002369:Integrin beta subunit, VWA domain, IPR012896:Integrin beta subunit, tail, IPR014836:Integrin beta subunit, cytoplasmic domain, IPR015812:Integrin beta subunit, IPR032695:Integrin domain, IPR013111:EGF-like domain, extracellular" CG1560 11-Aug-17 DroID_v2017_08 "Drer\itgb1b.2, Drer\itgb1b.1, Drer\itgb2, Drer\itgb7, Drer\im:7156467, Drer\itgb5, Drer\itgb4, Drer\itgb8, Drer\itgb3b, Drer\itgb1a, Drer\itgbl1, Drer\itgb1b, Drer\itgb6, Drer\itgb3a" - "Cele\pat-3, Cele\C05D9.3" "Xtro\itgb8, Xtro\itgb2, Xtro\itgb6, Xtro\itgb1, Xtro\itgb4, Xtro\itgbl1, Xtro\itgb3, Xtro\itgb7" "Mmus\Itgb6, Mmus\Itgb1, Mmus\Itgbl1, Mmus\Itgb8, Mmus\Itgb2l, Mmus\Itgb7, Mmus\Itgb5, Mmus\Itgb2, Mmus\Itgb4, Mmus\Itgb3" "Hsap\ITGB8, Hsap\ITGB1, Hsap\ITGBL1, Hsap\ITGB3, Hsap\ITGB4, Hsap\ITGB7, Hsap\ITGB6, Hsap\ITGB5, Hsap\ITGB2" " embryonic stage , embryonic stage | stage 15-16 , larval stage | third instar " " embryonic/larval hindgut

, muscle attachment site

, tendon cell | restricted & muscle fiber | vicinity of muscle attachment site

, embryonic/larval pharynx

, embryonic/larval midgut

" "visible,somatic clone,viable,male,lethal,lethal - all die before end of first instar larval stage,smell perception defective,recessive,partially lethal - majority die,wild-type,heat sensitive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,cell shape defective,partially,reduced,germline clone,rescuable maternal effect,flightless,lethal - all die before end of pupal stage,some die during pupal stage" ",haltere,amnioserosa,extended germ band embryo,visceral mesoderm,somatic muscle,central nervous system,muscle fiber,embryo | dorsal closure stage,germ band,muscle tendon junction,wing,neuromuscular junction,male genitalia,dorsal closure embryo,embryonic epidermis,bouton,egg chamber,chorion,follicle cell,eye,stomodeum,tendon cell,embryonic somatic muscle,germ layer,midgut primordium,embryonic/larval somatic muscle,embryonic/larval midgut,embryonic/first instar larval cuticle,cardial valve,Z disc,anterior midgut primordium,salivary gland common duct primordium,posterior midgut primordium,presumptive embryonic salivary gland,circular visceral muscle primordium,muscle attachment site,embryonic/larval visceral branch,gastric caecum,embryonic/larval proventriculus,abdominal segment border muscle,abdominal lateral longitudinal muscle,abdominal ventral longitudinal muscle,ventral nerve cord,embryonic dorsal epidermis,pericardial cell,dorsal superficial trachea,embryonic/larval salivary gland,leg,tergite,adult cuticle,ommatidium,rhabdomere,terminal tracheal cell,wing blade,interfollicle cell,female germline cyst,dorsal trunk primordium,stress fiber,filamentous actin,fascicle,embryonic heart cardioblast,vertical lobe of adult mushroom body,stage S14 oocyte,retina,pigment cell,anterior crossvein,crossvein,dorsal wing blade,ventral wing blade,hub cell,genitalia,dorsal medial muscle,posterior spiracle primordium,‘±,F11,male germline stem cell,dorsal multidendritic neuron ddaC |,dorsal multidendritic neuron ddaC,cardial cell | adult stage,border follicle cell" FBgn0011824 CG4038 - http://flybase.org/reports/FBgn0011824 - protein_coding_gene snoRNA binding ; GO:0030515 | inferred from sequence or structural similarity with UniProtKB:P32495 box H/ACA snoRNA binding ; GO:0034513 | inferred from biological aspect of ancestor with PANTHER:PTN000579935 rRNA pseudouridine synthesis ; GO:0031118 | inferred from sequence or structural similarity with UniProtKB:P32495 cellular response to starvation ; GO:0009267 | inferred from expression pattern snoRNA guided rRNA pseudouridine synthesis ; GO:0000454 | inferred from biological aspect of ancestor with PANTHER:PTN000579935 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay small nucleolar ribonucleoprotein complex ; GO:0005732 | inferred from sequence or structural similarity with UniProtKB:P32495 nucleoplasm ; GO:0005654 | inferred from direct assay box H/ACA snoRNP complex ; GO:0031429 | inferred from biological aspect of ancestor with PANTHER:PTN000579935 "GCR101 SnRNP, GCR 101, anon-Pen101, Pen101, GCR101, CG4038, dGAR1, CG4038-PA, Gar1" "IPR007504:H/ACA ribonucleoprotein complex, subunit Gar1/Naf1, IPR021154:H/ACA ribonucleoprotein complex, subunit Gar1, IPR009000:Translation protein, beta-barrel domain" CG4038 11-Aug-17 DroID_v2017_08 Drer\gar1 Scer\GAR1 Cele\Y66H1A.4 Xtro\gar1 Mmus\Gar1 Hsap\GAR1 "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0000140 asp abnormal spindle http://flybase.org/reports/FBgn0000140 "FBgn0014939, FBgn0062123" protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from sequence or structural similarity myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis inferred from physical interaction with Mlc-c calmodulin binding ; GO:0005516 | inferred from direct assay "centrosome localization ; GO:0051642 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype establishment of meiotic spindle localization ; GO:0051295 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype nuclear migration ; GO:0007097 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from direct assay actin filament reorganization involved in cell cycle ; GO:0030037 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from mutant phenotype kinetochore organization ; GO:0051383 | inferred from mutant phenotype astral microtubule nucleation ; GO:0030954 | inferred from mutant phenotype cystoblast division ; GO:0007282 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype germarium-derived oocyte differentiation ; GO:0030706 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity centrosome organization ; GO:0051297 | inferred from mutant phenotype" centrosome ; GO:0005813 | inferred from direct assay spindle pole ; GO:0000922 | inferred from direct assay microtubule organizing center ; GO:0005815 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay "CG6875, Asp, anon-96Aa, anon-WO0118547.279, asp, ASP, Dm Asp" "IPR000048:IQ motif, EF-hand binding site, IPR001715:Calponin homology domain, IPR013783:Immunoglobulin-like fold, IPR031549:Abnormal spindle-like microcephaly-associated protein, ASH domain" CG6875 11-Aug-17 DroID_v2017_08 "Drer\bmp1a, Drer\npsn, Drer\c6ast3, Drer\mep1a.1, Drer\drp2, Drer\aspm, Drer\LOC100003133, Drer\mep1a.2, Drer\mep1b, Drer\c6ast4, Drer\he2, Drer\c6ast1, Drer\tll1, Drer\he1a, Drer\LOC797085" - "Cele\nas-1, Cele\nas-13, Cele\nas-2, Cele\nas-14, Cele\nas-7, Cele\aspm-1, Cele\nas-8, Cele\ZC116.3, Cele\nas-6, Cele\Y19D10A.6, Cele\nas-12, Cele\nas-39, Cele\nas-15, Cele\nas-4" "Xtro\tll1, Xtro\LOC100492324, Xtro\LOC100489456, Xtro\mep1b, Xtro\cubn, Xtro\bmp1, Xtro\mep1a, Xtro\uvs.2, Xtro\accs, Xtro\tll2" "Mmus\Bmp1, Mmus\Cubn, Mmus\Astl, Mmus\Tll1, Mmus\Aspm, Mmus\Mep1a, Mmus\Mep1b, Mmus\Tll2" "Hsap\BMP1, Hsap\TLL2, Hsap\MEP1B, Hsap\MEP1A, Hsap\ASTL, Hsap\ASPM, Hsap\TLL1, Hsap\CUBN" embryonic stage && larval stage && adult stage "partially lethal - majority die,recessive,viable,female sterile,lethal,wild-type,maternal effect,mitotic cell cycle defective,male sterile,visible,meiotic cell cycle defective,male,cytokinesis defective,female semi-sterile,cold sensitive,lethal - all die before end of larval stage,some die during larval stage,female,semi-sterile,cell adhesion defective,neuroanatomy defective,increased cell death,somatic clone" "eye,macrochaeta,germline cyst,embryonic/larval brain,spindle | maternal effect,wing,spermatocyte & spindle,spermatocyte & aster,ovariole,egg chamber,oocyte nucleus,spermatocyte & spindleHd‘_1),centrosome,microtubule organizing center,larval brain & neuroblast & centrosome,larval brain & neuroblast & mitotic cell cycle,larval brain & neuroblast & aster,larval brain & neuroblast & spindle,Nebenkern,onion stage spermatid & nucleus,aster | male,spermatocyte & centrosome,meiotic telophase II & spindle,meiotic telophase II & contractile ring,fusome,imaginal disc,spermatid,spindle,embryonic/larval neuroblast,adult head,germarium & spindle,germarium & microtubule,nurse cell ring canal,germarium,actomyosin contractile ring | male,spermatocyte ring canal,oocyte,spermatocyte,spermatocyte & microtubule organizing center,spermatocyte & microtubule,spindle | ectopic,anaphase & condensed nuclear chromosome,mitotic cell cycle,optic lobe,optic lobe forming neuroblast,lamina,mitotic spindle | third instar larval stage,somatic clone | third instar larval stage,mitotic spindle | somatic clone | third instar larval stage‘±Tub84B.PC" FBgn0034246 Dcr-2 Dicer-2 http://flybase.org/reports/FBgn0034246 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006935, InterPro:IPR011545 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006935 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ribonuclease III activity ; GO:0004525 | inferred from biological aspect of ancestor with PANTHER:PTN000383724 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V9K7 siRNA binding ; GO:0035197 | inferred from direct assay double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from direct assay" "RNA interference ; GO:0016246 | inferred from direct assay pre-miRNA processing ; GO:0031054 | NOT inferred from direct assay chromatin silencing ; GO:0006342 | inferred from mutant phenotype mRNA cleavage ; GO:0006379 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from mutant phenotype dosage compensation by hyperactivation of X chromosome ; GO:0009047 | inferred from genetic interaction with roX2, roX1 production of siRNA involved in RNA interference ; GO:0030422 | inferred from direct assay siRNA loading onto RISC involved in RNA interference ; GO:0035087 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype targeting of mRNA for destruction involved in RNA interference ; GO:0030423 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | traceable author statement positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype detection of virus ; GO:0009597 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype cellular response to virus ; GO:0098586 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay RISC complex ; GO:0016442 | inferred from direct assay "Dcr-2, Dicer, DCR-2, CG6493, dcr-2, dicer, DCR2, dicer2, DICER, cg6493, dcr2, Dcr2, Dicer2, dic2, Dcr, dcr, dDcr2, dmDcr-2, dicer-2" "IPR000999:Ribonuclease III domain, IPR001650:Helicase, C-terminal, IPR003100:PAZ domain, IPR005034:Dicer dimerisation domain, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014720:Double-stranded RNA-binding domain, IPR006935:Helicase/UvrB, N-terminal" CG6493 11-Aug-17 DroID_v2017_08 Drer\dicer1 Scer\MPH1 Cele\dcr-1 Xtro\dicer1 Mmus\Dicer1 Hsap\DICER1 "locomotor behavior defective,sleep defective,RU486 conditional,touch sensitivity defective,neuroanatomy defective,viable,lethal,locomotor rhythm defective,short lived,male,heat sensitive,visible,flightless,some die during pupal stage,flight defective,chemical resistant,partially lethal,neurophysiology defective,lethal - all die during pupal stage,partially lethal - majority die,learning defective,courtship behavior defective,grooming behavior defective,female,mating behavior defective,planar polarity defective,progressive,gravitaxis defective,partially lethal - majority live,male sterile,meiotic cell cycle defective,wild-type,immune response defective,recessive,stress response defective,suppressor of variegation,dominant,conditional,partially" "dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage1003.3, mriGD7508,sensory dendrite | larval stage, with Nmdar1GD2808, 1003.3,sensory dendrite | larval stage, with Nmdar2GD3192, 1003.3,sensory dendrite | larval stage1003.3, rpkGD3621,sensory dendrite | larval stage1003.3, naGD1172,sensory dendrite | larval stage1003.3, nompCKK105819,wing,wing margin bristle,H zoneMef2.PR, Zasp52KK101276,indirect flight muscle,myofibrilMef2.PR, Zasp52KK101276,Z discMef2.PR, Zasp52KK101276,M bandMef2.PR, Zasp52KK101276,H zoneMef2.PR, Zasp52dsRNA.ex16.UAS,myofibrilMef2.PR, Zasp66KK112973,Z discMef2.PR, Zasp66KK112973,M bandMef2.PR, Zasp66KK112973,posterior compartment,heat sensitive,1st posterior cell,anterior crossvein,mitochondrion, with Aats-serdsRNA.UAS.WIZ, ,mitochondrial matrix, with Aats-serdsRNA.UAS.WIZ, ,mitochondrial crista, with Aats-serdsRNA.UAS.WIZ, ,ommatidium,rhabdomere, with Cep89KK103260, GMR.PF,mitochondrion, with Cep89KK103260, GMR.PF,eye photoreceptor cell,wing vein,wing hair,embryonic/larval neuromuscular junction | larval stage,embryonic/larval neuromuscular junction | third instar larval stage,presynaptic active zoneelav.PU, simjKK107461,myofibril, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,striated muscle thin filament, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,striated muscle myosin thick filament, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,sarcomere, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,M band, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,Z disc, with DAAMEx1, DAAMdsRNA.UAS.T129M, UH3,Nebenkern,primary spermatocyte,onion stage spermatid,apterous-expressing neuron of the lateral cluster of the thorax,septate junction, with McrKK104742, ap-md544" FBgn0002576 lz lozenge http://flybase.org/reports/FBgn0002576 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000040 transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | non-traceable author statement transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with run inferred from sequence or structural similarity with HGNC:10471 DNA binding ; GO:0003677 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" hemopoiesis ; GO:0030097 | traceable author statement positive regulation of compound eye retinal cell programmed cell death ; GO:0046672 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement embryonic hemopoiesis ; GO:0035162 | inferred from mutant phenotype cell fate determination ; GO:0001709 | non-traceable author statement lymph gland crystal cell differentiation ; GO:0035170 | traceable author statement embryonic crystal cell differentiation ; GO:0035165 | inferred from expression pattern embryonic hemocyte differentiation ; GO:0035163 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | traceable author statement embryonic crystal cell differentiation ; GO:0035165 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from genetic interaction with svp eye morphogenesis ; GO:0048592 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype embryonic crystal cell differentiation ; GO:0035165 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from genetic interaction with B compound eye development ; GO:0048749 | inferred from mutant phenotype scab formation ; GO:0035314 | inferred from mutant phenotype larval lymph gland hemocyte differentiation ; GO:0035168 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | traceable author statement cell differentiation ; GO:0030154 | traceable author statement compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype crystal cell differentiation ; GO:0042688 | traceable author statement imaginal disc-derived female genitalia development ; GO:0007486 | inferred from mutant phenotype antennal development ; GO:0007469 | traceable author statement signal transduction ; GO:0007165 | non-traceable author statement oogenesis ; GO:0048477 | traceable author statement wound healing ; GO:0042060 | inferred from mutant phenotype spermathecum morphogenesis ; GO:0035211 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement nucleus ; GO:0005634 | inferred by curator from GO:0003677 nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with run inferred from sequence or structural similarity with HGNC:10471 inferred from sequence or structural similarity with MGI:MGI:99829 "Lz, amx, fs(1)M69, spe, fs(1)A1569, CG1689, lz" "IPR000040:Acute myeloid leukemia 1 protein (AML1)/Runt, IPR008967:p53-like transcription factor, DNA-binding, IPR012346:p53/RUNT-type transcription factor, DNA-binding domain, IPR013524:Runt domain" CG1689 11-Aug-17 DroID_v2017_08 "Drer\runx1, Drer\runx3, Drer\runx2a, Drer\runx2b" - Cele\rnt-1 "Xtro\runx2, Xtro\runx1, Xtro\runx3" "Mmus\Runx2, Mmus\Runx1, Mmus\Runx3" "Hsap\RUNX3, Hsap\RUNX2, Hsap\RUNX1" "increased cell death,visible,recessive,semidominant,female sterile,eye color defective,viable,fertile,dominant,male fertile,female fertile,heat sensitive,lethal,female,wild-type,smell perception defective,increased cell number,decreased cell death,cold sensitive,male sterile,poor,partially,wound healing defective,neuroanatomy defective,male,male semi-sterile,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "third segment of antenna,ommatidium,eye,lens,interommatidial bristle,pigment cell,cone cell,optic lobe,photoreceptor cell R7,spermathecum,female accessory gland,unguis,ovary,sensillum basiconicum of antennal segment 3,sensillum trichodeum of antennal segment 3,maxillary palp sensillum basiconicum,eye disc,eye photoreceptor cell,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,posterior,lamina,retina,sensillum coeloconicum of antennal segment 3,cell body rind of lamina,prothoracic unguis,mesothoracic unguis,metathoracic unguis,photoreceptor cell R2,photoreceptor cell R5,ectopic,tarsal segment,spermathecal duct,supernumerary,heat sensitive,sensillum basiconicum,crystal cell,antennal sense organ,precursor,secondary pigment cell,tertiary pigment cell,temperature conditional,antenna,maxillary palpus,embryonic/larval optic stalk,sensillum trichodeum,medulla,lobula,lobula plate,pulvillus,cell non-autonomous,somatic clone,pigment granule | cell non-autonomous | somatic clone,ommatidial precursor cluster,antennal lobe glomerulus DL2,antennal lobe glomerulus V,antennal lobe glomerulus VL2,antennal lobe glomerulus,eye-antennal disc,sensillum coeloconicum & antennal segment 3,fascicle & antennal segment 3,antennal commissure,adult antennal nerve,hemocyte,plasmatocyte,dorsal closure embryo" DRSC18790 IE 0.46296584 -2.834996802 -0.281992306 -1.696294956 -0.793218918 0.713147481 FBgn0259752 ms(3)Z2203 - http://flybase.org/reports/FBgn0259752 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "162-039, ms(3)Z2203, ms(3)162-39" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,viable,meiotic cell cycle defective,male" "Y chromosome loop,Nebenkern,spermatid,nucleus & spermatid,chromosome & primary spermatocyte,spindle" FBgn0261875 Z2-0557 - http://flybase.org/reports/FBgn0261875 gene - sleep ; GO:0030431 | inferred from mutant phenotype - Z2-0557 - - 11-Aug-17 DroID_v2017_08 - - - - - - behavior defective FBgn0015574 alpha-Est6 alpha-Esterase-6 http://flybase.org/reports/FBgn0015574 - protein_coding_gene - - - "Esterase-6, alphaE6, aE6, G, F, E, CG1108, alpha-Est6, DmalphaE6" "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG1108 11-Aug-17 DroID_v2017_08 "Drer\nlgn2b, Drer\nlgn1, Drer\cell, Drer\nlgn3a, Drer\cel.1, Drer\si:ch211-93f2.1, Drer\nlgn4a, Drer\ces3, Drer\ces2, Drer\nlgn4b, Drer\nlgn3b, Drer\nlgn2a" - "Cele\T28C12.5, Cele\ace-1, Cele\F15A8.6, Cele\C52A10.1, Cele\F56C11.6, Cele\B0238.1, Cele\ace-2, Cele\T28C12.4, Cele\Y71H2AM.13, Cele\F13H6.3, Cele\F07C4.12, Cele\K11G9.3, Cele\B0238.7" "Xtro\nlgn3, Xtro\nlgn2, Xtro\cel, Xtro\nlgn4x, Xtro\ces2, Xtro\ces3, Xtro\LOC100494782" "Mmus\Ces2c, Mmus\Ces1f, Mmus\Ces1c, Mmus\Nlgn1, Mmus\Ces2f, Mmus\Ces2e, Mmus\Ces2b, Mmus\Ces1h, Mmus\Ces1g, Mmus\Nlgn3, Mmus\Ces2a, Mmus\Cel, Mmus\Nlgn2, Mmus\Ces1e, Mmus\Ces4a, Mmus\Ces3a, Mmus\Ces1d, Mmus\Ces2g, Mmus\Ces1b, Mmus\Ces2h, Mmus\Ces3b, Mmus\Ache, Mmus\Ces5a" "Hsap\ACHE, Hsap\CES3, Hsap\CES5A, Hsap\NLGN2, Hsap\NLGN1, Hsap\CES2, Hsap\NLGN3, Hsap\CEL, Hsap\NLGN4Y, Hsap\CES1, Hsap\NLGN4X, Hsap\CES4A" viable FBgn0036641 Smn survival motor neuron http://flybase.org/reports/FBgn0036641 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR010304 alpha-actinin binding ; GO:0051393 | inferred from physical interaction with Actn "neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype embryo development ; GO:0009790 | inferred from mutant phenotype stem cell proliferation ; GO:0072089 | inferred from mutant phenotype ribonucleoprotein complex assembly ; GO:0022618 | inferred from mutant phenotype basal protein localization ; GO:0045175 | inferred from mutant phenotype cytoplasmic U snRNP body assembly ; GO:1990194 | inferred from mutant phenotype cytoplasmic mRNA processing body assembly ; GO:0033962 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype AMPA glutamate receptor clustering ; GO:0097113 | inferred from mutant phenotype stem cell differentiation ; GO:0048863 | inferred from mutant phenotype excitatory postsynaptic potential ; GO:0060079 | inferred from mutant phenotype skeletal muscle thin filament assembly ; GO:0030240 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype positive regulation of synaptic transmission, cholinergic ; GO:0032224 | inferred from mutant phenotype terminal cell fate specification, open tracheal system ; GO:0035154 | inferred from mutant phenotype stem cell division ; GO:0017145 | inferred from mutant phenotype spliceosomal snRNP assembly ; GO:0000387 | inferred from direct assay spliceosomal snRNP assembly ; GO:0000387 | inferred from mutant phenotype oocyte morphogenesis ; GO:0048601 | inferred from mutant phenotype larval development ; GO:0002164 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay Gemini of coiled bodies ; GO:0097504 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay SmD-containing SMN-Sm protein complex ; GO:0034730 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay SMN-Gemin2 complex ; GO:0034718 | inferred from direct assay cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay I band ; GO:0031674 | inferred from direct assay Cajal body ; GO:0015030 | inferred from direct assay SMN complex ; GO:0032797 | inferred from genetic interaction with Gem3 "l(3)73Ao, smn, dSMN, DmSMN, CG16725, Smn, SMN" "IPR002999:Tudor domain, IPR010304:Survival motor neuron" CG16725 11-Aug-17 DroID_v2017_08 Drer\smn1 - Cele\smn-1 Xtro\smn2 Mmus\Smn1 "Hsap\SMN1, Hsap\SMN2" "small body,locomotor behavior defective,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live,neuroanatomy defective,developmental rate defective,some die during third instar larval stage,partially lethal - majority die,some die during pupal stage,flight defective,jumping defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die during pupal stage,neurophysiology defective,size defective,locomotor rhythm defective,lethal - all die before end of pupal stage,lethal,visible,germline clone,non-rescuable maternal effect,female sterile,uncoordinated,increased cell death,flightless,viable,fertile" "NMJ bouton,NMJ bouton | third instar larval stage,embryonic/larval neuromuscular junction,embryonic/larval somatic muscle,wing vein L4,wing vein L5,posterior crossvein,dorsal medial muscle,indirect flight muscle,indirect flight muscle motor neuron,striated muscle thin filament,embryonic/larval trachea,tracheal lumen" FBgn0005278 Sam-S S-adenosylmethionine Synthetase http://flybase.org/reports/FBgn0005278 "FBgn0011287, FBgn0031218" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002133 methionine adenosyltransferase activity ; GO:0004478 | inferred from sequence or structural similarity with EMBL:J03477 inferred from sequence or structural similarity with protein_id:AAA42106.1 methionine adenosyltransferase activity ; GO:0004478 | inferred from biological aspect of ancestor with PANTHER:PTN000239344 chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp inferred from genetic interaction with Chi determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype S-adenosylmethionine biosynthetic process ; GO:0006556 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from genetic interaction with Bx cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000239344 "Su(z)5, CG2674, METK, SamS, Sam-S, M(2)21A-B, m(2)21ab, M(2)21AB, Sams" "IPR002133:S-adenosylmethionine synthetase, IPR022628:S-adenosylmethionine synthetase, N-terminal, IPR022629:S-adenosylmethionine synthetase, central domain, IPR022630:S-adenosylmethionine synthetase, C-terminal, IPR022631:S-adenosylmethionine synthetase, conserved site, IPR022636:S-adenosylmethionine synthetase superfamily" CG2674 11-Aug-17 DroID_v2017_08 "Drer\mat2al, Drer\mat2aa, Drer\mat2ab, Drer\mat1a" "Scer\SAM1, Scer\SAM2" "Cele\sams-4, Cele\sams-5, Cele\sams-1, Cele\sams-3" "Xtro\mat2a, Xtro\mat1a" "Mmus\Mat2a, Mmus\Mat1a" "Hsap\MAT2A, Hsap\MAT1A" " embryonic stage -- adult stage , adult stage | female " ovary

"visible,partially lethal - majority die,some die during pupal stage,suppressor of variegation,dominant,lethal,recessive,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage" "trichogen cell,mesothoracic tergum,macrochaeta,germline clone,scutellar bristle,tergite,male genitalia,eye" DRSC00758 E 0.630570168 1.319451612 1.036792331 -4.220513748 -0.485952449 0.404377586 FBgn0040857 CG11366 - http://flybase.org/reports/FBgn0040857 protein_coding_gene - - - CG11366 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0085438 CG34409 - http://flybase.org/reports/FBgn0085438 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG34409, CG12949, CG31411, c-SP12, SP12, CG31412" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG34409 11-Aug-17 DroID_v2017_08 - - "Cele\try-3, Cele\try-1" - - - "viable,visible" trichogen cell FBgn0004509 Fur1 Furin 1 http://flybase.org/reports/FBgn0004509 "FBgn0010236, FBgn0024579, FBgn0039334" protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from genetic interaction with Fur2 serine-type endopeptidase activity ; GO:0004252 | inferred from direct assay serine-type endopeptidase activity ; GO:0004252 | non-traceable author statement "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000209, InterPro:IPR002884 synaptic target recognition ; GO:0008039 | inferred from mutant phenotype presynaptic membrane organization ; GO:0097090 | inferred from mutant phenotype postsynaptic membrane organization ; GO:0001941 | inferred from mutant phenotype glutamate receptor clustering ; GO:0097688 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:8568 inferred from sequence or structural similarity with SGD:S000005182 inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with Fur2 "Furin, fur[1], CG10772, Furl, dFur1, Dfur1, fur1, furin, dKLIP-1, dFurin 1, l(3)rL205, Klip1, Fur1, fur-1, Dfurin1" "IPR000209:Peptidase S8/S53 domain, IPR002884:Proprotein convertase, P, IPR006212:Furin-like repeat, IPR008979:Galactose-binding domain-like, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR009030:Growth factor receptor cysteine-rich domain, IPR015500:Peptidase S8, subtilisin-related, IPR032815:Peptidase S8, pro-domain, IPR034182:Kexin/furin catalytic domain, IPR022398:Peptidase S8, subtilisin, His-active site, IPR023827:Peptidase S8, subtilisin, Asp-active site, IPR023828:Peptidase S8, subtilisin, Ser-active site" CG10772 11-Aug-17 DroID_v2017_08 "Drer\fras1, Drer\furinb, Drer\pcsk2, Drer\pcsk5a, Drer\rspo3, Drer\pcsk5b, Drer\pcsk7, Drer\LOC100330575, Drer\pcsk1, Drer\furina" "Scer\RRT12, Scer\YSP3, Scer\KEX2" "Cele\kpc-1, Cele\egl-3, Cele\aex-5, Cele\bli-4" "Xtro\pcsk4, Xtro\pcsk2, Xtro\pcsk5, Xtro\fras1, Xtro\pcsk1, Xtro\rspo3, Xtro\pcsk6, Xtro\pcsk7, Xtro\furin" "Mmus\Rspo4, Mmus\Fras1, Mmus\Pcsk4, Mmus\Pcsk1, Mmus\Rspo3, Mmus\Pcsk6, Mmus\Furin, Mmus\Rspo1, Mmus\Pcsk5, Mmus\Pcsk7, Mmus\Pcsk2" "Hsap\PCSK6, Hsap\RSPO3, Hsap\PCSK5, Hsap\PCSK2, Hsap\PCSK1, Hsap\RSPO4, Hsap\FURIN, Hsap\PCSK4, Hsap\RSPO1, Hsap\FRAS1, Hsap\PCSK7" " embryonic stage , adult stage , adult stage && oogenesis stage , embryonic stage | stage 16 , adult stage | female " " embryonic/larval hindgut

, embryonic central nervous system | restricted

, labral segment

, adult brain cortex

, anal pad

, nurse cell

, central nervous system | restricted

, oocyte

, oenocyte

, embryonic/larval pharynx

, follicle cell

, embryonic/larval posterior spiracle

, central nervous system

, fat body

, subesophageal ganglion

, embryonic/larval trachea

, oviduct

, tracheal pit

, antenno-maxillary complex

" "viable,fertile,lethal,recessive,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0062530 l(3)88EFb lethal (3) 88EFb http://flybase.org/reports/FBgn0062530 gene - - - l(3)88EFb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" FBgn0038341 AdamTS-A ADAM metallopeptidase with thrombospondin type 1 motif A http://flybase.org/reports/FBgn0038341 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001590, InterPro:IPR002870, InterPro:IPR010294, InterPro:IPR012314 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002870, InterPro:IPR012314, InterPro:IPR013273" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001590, InterPro:IPR002870 extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype pole cell migration ; GO:0007280 | inferred from mutant phenotype larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype mesodermal cell migration ; GO:0008078 | inferred from mutant phenotype" proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR013273 "CG6107, CT19033, CG14869, AdamTS-A" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR001590:Peptidase M12B, ADAM/reprolysin, IPR002870:Peptidase M12B, propeptide, IPR010294:ADAM-TS Spacer 1, IPR012314:Peptidase M12B, GON-ADAMTSs, IPR013273:Peptidase M12B, ADAM-TS, IPR024079:Metallopeptidase, catalytic domain" CG14869 11-Aug-17 DroID_v2017_08 "Drer\LOC100001991, Drer\adamts8a, Drer\adamtsl2, Drer\adamts7, Drer\adamts9, Drer\adamts18, Drer\adamts2, Drer\adamts13, Drer\adamtsl3, Drer\adamts10, Drer\thsd7bb, Drer\adamts1, Drer\adamts5, Drer\LOC568792, Drer\adamts12, Drer\adamtsl5, Drer\LOC100002059, Drer\adamts15a, Drer\adamts6" - Cele\gon-1 "Xtro\adamts3, Xtro\adamts14, Xtro\adamts1, Xtro\adamts16, Xtro\adamts6, Xtro\adamts9, Xtro\adamts7, Xtro\adamts20, Xtro\adamts4, Xtro\adamts18, Xtro\adamts2, Xtro\adamts13, Xtro\adamts5, Xtro\adamts15, Xtro\adamts8, Xtro\adamts12" "Mmus\Adamts6, Mmus\Adamts10, Mmus\Adamts14, Mmus\Adamts20, Mmus\Thsd7a, Mmus\Sspo, Mmus\Adamts18, Mmus\Adamts8, Mmus\Adamts7, Mmus\Adamtsl4, Mmus\Adamts5, Mmus\Adamtsl1, Mmus\Adamts13, Mmus\Adamts15, Mmus\Adamts12, Mmus\Adamts19, Mmus\Adamts4, Mmus\Adamts16, Mmus\Adamts1, Mmus\Adamts3, Mmus\Adamts9, Mmus\Thsd4, Mmus\Adamtsl5, Mmus\Adamts2" "Hsap\ADAMTS9, Hsap\ADAMTS14, Hsap\ADAMTS5, Hsap\ADAMTS8, Hsap\ADAMTS3, Hsap\ADAMTS15, Hsap\ADAMTS4, Hsap\ADAMTSL1, Hsap\ADAMTS6, Hsap\ADAMTSL5, Hsap\ADAMTS16, Hsap\THSD7B, Hsap\ADAMTS12, Hsap\ADAMTS19, Hsap\ADAMTS2, Hsap\ADAMTS7, Hsap\ADAMTS17, Hsap\THSD4, Hsap\ADAMTS1, Hsap\ADAMTS18, Hsap\ADAMTSL4, Hsap\ADAMTS20, Hsap\ADAMTS13, Hsap\ADAMTS10" "cell migration defective,viable" "germline cell,longitudinal visceral muscle primordium,embryonic/larval visceral branch,embryonic/larval salivary gland" DRSC14992 K -0.380311723 0.363173196 0.497270764 0.318829286 1.827039026 0.50338303 FBgn0028345 l(1)G0213 lethal (1) G0213 http://flybase.org/reports/FBgn0028345 gene - - - l(1)G0213 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0259356 EP-773 - http://flybase.org/reports/FBgn0259356 gene - - - EP-773 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing vein,wing hair,wing margin" FBgn0038739 CG4686 - http://flybase.org/reports/FBgn0038739 protein_coding_gene - - - "BcDNA:AT09463, CG4686" IPR006696:Protein of unknown function DUF423 CG4686 11-Aug-17 DroID_v2017_08 Drer\tmem256 - Cele\Y106G6H.8 Xtro\tmem256 Mmus\Tmem256 Hsap\TMEM256 "viable,fertile" FBgn0002624 M(3)96CF Minute (3) 96CF http://flybase.org/reports/FBgn0002624 - gene - - - "M(3)j, M[[j]], M(3)Sp, M(3)96CF" - - 11-Aug-17 DroID_v2017_08 - - - - - - "Minute,dominant,visible,female sterile,male fertile,developmental rate defective" "macrochaeta,wing,wing vein,adult abdomen,posterior dorsocentral bristle,posterior scutellar bristle,femur & macrochaeta" FBgn0034230 CG4853 - http://flybase.org/reports/FBgn0034230 protein_coding_gene Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | inferred from sequence or structural similarity with HGNC:24246 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from sequence or structural similarity with HGNC:24246 mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG4853 "IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR023578:Ras guanine nucleotide exchange factor domain, IPR019804:Ras guanine-nucleotide exchange factor, conserved site" CG4853 11-Aug-17 DroID_v2017_08 "Drer\rasgef1bb, Drer\rasgef1ba" Scer\CDC25 Cele\R05G6.10 "Xtro\rasgef1a, Xtro\rasgef1b" "Mmus\Rasgef1a, Mmus\Rasgef1b, Mmus\Rasgef1c" "Hsap\RASGEF1C, Hsap\RASGEF1A, Hsap\RASGEF1B" "neuroanatomy defective,viable" "antennal lobe,adult mushroom body" FBgn0011481 Ssdp Sequence-specific single-stranded DNA-binding protein http://flybase.org/reports/FBgn0011481 FBgn0038580 protein_coding_gene "single-stranded DNA binding ; GO:0003697 | inferred from electronic annotation with InterPro:IPR008116 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000972842 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from biological aspect of ancestor with PANTHER:PTN000972842" "neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from genetic interaction with Chi wing disc development ; GO:0035220 | inferred from genetic interaction with ap positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000972842" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000972842 "CG7187, ssdp, l(3)neo48, Ssdp" "IPR006594:LIS1 homology motif, IPR008116:Sequence-specific single-strand DNA-binding protein" CG7187 11-Aug-17 DroID_v2017_08 "Drer\ssbp4, Drer\si:ch211-130m23.3, Drer\ssbp3b, Drer\ssbp2, Drer\ssbp3a, Drer\zgc:110158" - "Cele\sam-10, Cele\Y53F4B.5" "Xtro\ssbp2, Xtro\ssbp4, Xtro\ssbp3" "Mmus\Ssbp3, Mmus\Ssbp4, Mmus\Ssbp2" "Hsap\SSBP4, Hsap\SSBP2, Hsap\SSBP3" "lethal,recessive,partially lethal - majority die,partially,germline clone,visible,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "anterior scutellar bristle,supernumerary,posterior scutellar bristle,wing,mesothoracic tergum,macrochaeta,somatic clone,dorsal,cell non-autonomous,wing margin bristle,ectopic,adult cuticle,scutellar bristle" FBgn0005129 l(1)w lethal (1) w http://flybase.org/reports/FBgn0005129 - gene - - - l(1)w - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female,recessive" FBgn0002723 Met Methoprene-tolerant http://flybase.org/reports/FBgn0002723 - protein_coding_gene transcription factor binding ; GO:0008134 | inferred from physical interaction with ftz-f1 juvenile hormone binding ; GO:0005500 | traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ftz-f1 juvenile hormone receptor activity ; GO:0004880 | inferred from mutant phenotype juvenile hormone binding ; GO:0005500 | inferred from direct assay "regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay regulation of developmental process ; GO:0050793 | inferred from mutant phenotype negative regulation of programmed cell death ; GO:0043069 | inferred from genetic interaction with gce positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement" nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "DmMet, Met, met, Mett, CG1705, Rst(1)JH, MET, bHLHe59, Met/Met1" "IPR000014:PAS domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG1705 11-Aug-17 DroID_v2017_08 "Drer\arntl1a, Drer\ncoa1, Drer\clockb, Drer\ncoa3, Drer\ncoa2, Drer\arntl1b" - "Cele\aha-1, Cele\ref-1" Xtro\arntl "Mmus\Ncoa3, Mmus\Clock, Mmus\Arntl2, Mmus\Arntl" "Hsap\ARNTL, Hsap\PASD1, Hsap\ARNTL2" " adult stage | female , embryonic stage , embryonic stage -- adult stage " "chemical resistant,visible,partially lethal - majority die,some die during larval stage,lethal - all die before end of larval stage,lethal,viable,dominant,recessive,wild-type,chemical sensitive,female fertile,reduced,lethal - all die before end of pupal stage,partially,some die during pupal stage,female semi-sterile,semidominant" "eye,embryonic/larval fat body | wandering third instar larval stage,ommatidium,abdominal sternite bristle,male genitalia,stage S8 oocyte,stage S9 oocyte,stage S10 oocyte,stage S11 oocyte,stage S12 oocyte,stage S13 oocyte,stage S14 oocyte,ovary,optic lobe,photoreceptor cell R7,photoreceptor cell R8,lobula,lobula plate,tarsal segment 1 & joint,tarsal segment 2 & joint,leg sensillum" FBgn0086424 l(3)CHh lethal (3) CHh http://flybase.org/reports/FBgn0086424 gene - - - l(3)CHh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0262319 mir-1000 mir-1000 stem loop http://flybase.org/reports/FBgn0262319 miRNA_gene - "negative regulation of glutamate secretion, neurotransmission ; GO:1903295 | inferred from mutant phenotype" - "miR-1000, dme-mir-1000, mir-1000, MIR-1000, CR43026" - CR43026 11-Aug-17 DroID_v2017_08 - - - - - - "viable,visible,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,wing vein,wing vein L5,wing margin" FBgn0030241 feo fascetto http://flybase.org/reports/FBgn0030241 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR007145 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "l(1)9Fe, CG11207, l(1)BP1, Q54, EA86, feo, Feo, PRC1" "IPR007145:Microtubule-associated protein, MAP65/Ase1/PRC1" CG11207 11-Aug-17 DroID_v2017_08 "Drer\prc1a, Drer\prc1b, Drer\zgc:86764" Scer\ASE1 Cele\spd-1 "Xtro\prc1, Xtro\jakmip3, Xtro\prc1.2" Mmus\Prc1 Hsap\PRC1 "lethal,recessive,cytokinesis defective,cell lethal,germline clone,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,visible,cold sensitive,neuroanatomy defective" "posterior supraalar bristle,cold sensitive,mitotic telophase & spindle,mitotic telophase & contractile ring,spermatocyte,testis,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,epithelium,female germline cyst" FBgn0036746 Crtc CREB-regulated transcription coactivator http://flybase.org/reports/FBgn0036746 protein_coding_gene cAMP response element binding protein binding ; GO:0008140 | inferred from biological aspect of ancestor with PANTHER:PTN001006040 protein homotetramerization ; GO:0051289 | inferred from electronic annotation with InterPro:IPR024783 response to starvation ; GO:0042594 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN001006040 positive regulation of CREB transcription factor activity ; GO:0032793 | inferred from biological aspect of ancestor with PANTHER:PTN001006040 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "dTORC, CG6064, TORC, ORE-12, cg6064, CRTC, TORC1, Crtc" "IPR024783:Transducer of regulated CREB activity, N-terminal, IPR024785:Transducer of regulated CREB activity, C-terminal, IPR024786:CREB-regulated transcription coactivator, IPR015943:WD40/YVTN repeat-like-containing domain" CG6064 11-Aug-17 DroID_v2017_08 "Drer\crtc1b, Drer\crtc3, Drer\crtc1a, Drer\crtc2" - Cele\crtc-1 "Xtro\crtc1, Xtro\crtc3" "Mmus\Crtc1, Mmus\Crtc2, Mmus\Crtc3" "Hsap\CRTC2, Hsap\CRTC3, Hsap\CRTC1" "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,short lived,stress response defective" "eye,ommatidium,interommatidial bristle" FBgn0028500 Rich RIC1 homolog http://flybase.org/reports/FBgn0028500 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000507542 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence or structural similarity with SGD:S000004029 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence or structural similarity with UniProtKB:Q4ADV7 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab6 "protein localization to synapse ; GO:0035418 | inferred from mutant phenotype regulation of postsynaptic membrane potential ; GO:0060078 | inferred from mutant phenotype regulation of Rab protein signal transduction ; GO:0032483 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from genetic interaction with Rab6 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with UniProtKB:Q4ADV7 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN000507542 R7 cell development ; GO:0045467 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with UniProtKB:Q4ADV7 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000507542 negative regulation of cellular protein catabolic process ; GO:1903363 | inferred from sequence or structural similarity with UniProtKB:Q4ADV7" Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000507542 RIC1-RGP1 guanyl-nucleotide exchange factor complex ; GO:0034066 | inferred from sequence or structural similarity with UniProtKB:Q4ADV7 RIC1-RGP1 guanyl-nucleotide exchange factor complex ; GO:0034066 | inferred from biological aspect of ancestor with PANTHER:PTN000507542 cytoplasmic vesicle ; GO:0031410 | inferred from direct assay protein complex ; GO:0043234 | inferred from sequence or structural similarity with UniProtKB:Q4ADV7 Golgi apparatus ; GO:0005794 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000507542 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:Q4ADV7 membrane ; GO:0016020 | inferred from sequence or structural similarity with UniProtKB:Q4ADV7 "BcDNA:GH03694, BcDNAGH03694, Rich, CG9063, rich, 3L6" "IPR017986:WD40-repeat-containing domain, IPR009771:Ribosome control protein 1, IPR015943:WD40/YVTN repeat-like-containing domain" CG9063 11-Aug-17 DroID_v2017_08 Drer\ric1 Scer\RIC1 Cele\R06F6.8 Xtro\ric1 Mmus\Ric1 Hsap\RIC1 "lethal,recessive,neurophysiology defective,somatic clone,neuroanatomy defective,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "optic cartridge,somatic clone,photoreceptor cell R7,cell autonomous,trichogen cell,mesothoracic tergum" FBgn0003475 spir spire http://flybase.org/reports/FBgn0003475 "FBgn0029122, FBgn0032854, FBgn0040997" protein_coding_gene "actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR003124, InterPro:IPR029901 protein binding ; GO:0005515 | inferred from physical interaction with wash protein binding ; GO:0005515 | inferred from physical interaction with mon2 microtubule binding ; GO:0008017 | inferred from mutant phenotype actin binding ; GO:0003779 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with egg" vesicle-mediated transport ; GO:0016192 | inferred from electronic annotation with InterPro:IPR029901 actin filament organization ; GO:0007015 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype pole plasm RNA localization ; GO:0007316 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | traceable author statement actin nucleation ; GO:0045010 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | traceable author statement chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype actin filament-based process ; GO:0030029 | inferred from direct assay regulation of cytoskeleton organization ; GO:0051493 | inferred from direct assay oogenesis ; GO:0048477 | traceable author statement pole plasm assembly ; GO:0007315 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | non-traceable author statement pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement actin cytoskeleton organization ; GO:0030036 | traceable author statement actin filament network formation ; GO:0051639 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "Spire, spir, p150Spir, p150-Spir, 38C.37, 38C.34, l(2)08327, CG10076, Spir, CG18621, spire, NP2788" "IPR029901:Protein Spire, IPR003124:WH2 domain, IPR011019:KIND domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10076 11-Aug-17 DroID_v2017_08 "Drer\zgc:114123, Drer\spire1a, Drer\spire2" - - Xtro\spire2 "Mmus\Spire1, Mmus\Spire2" "Hsap\SPIRE1, Hsap\SPIRE2" "oxidative stress response defective,female sterile,viable,grandchildless,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,lethal,maternal effect,female semi-sterile" "embryo,germline clone,maternal effect,posterior,stage S8 oocyte & microtubule,egg chamber,chorion | maternal effect,pole cell,embryonic abdomen,egg,follicle cell,dorsal appendage,blastoderm embryo,karyosome,oocyte nucleus,oocyte,filamentous actin | oogenesis stage S9,actin filamentExel6046),actin filament, with Df(2L)Exel6046, nos.UTR.THsimVP16" FBgn0002622 RpS3 Ribosomal protein S3 http://flybase.org/reports/FBgn0002622 FBgn0010267 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004044, InterPro:IPR009019 oxidized purine nucleobase lesion DNA N-glycosylase activity ; GO:0008534 | inferred from direct assay DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000205059 structural constituent of ribosome ; GO:0003735 | inferred from direct assay oxidized purine DNA binding ; GO:0032357 | inferred from direct assay damaged DNA binding ; GO:0003684 | inferred from direct assay" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001351, InterPro:IPR005703 DNA repair ; GO:0006281 | inferred from genetic interaction with EchoBASE:EB0325 inferred from genetic interaction with EchoBASE:EB0645,EchoBASE:EB1066 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement" small ribosomal subunit ; GO:0015935 | inferred from electronic annotation with InterPro:IPR005703 nuclear matrix ; GO:0016363 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay "RpS3, M(3)95A, Rps3, M(3)w, S3, X72921, DmRpS3, dS3, RS3, rpS3, M(3R)w, Mw, M[[w]], M(3)Fla, M(3)B2, M(3)B, M(3)124, CG6779, rps3, M95A, RPS3, 6779, Rp S3, M, chr3R:19185518..19185701, IP15838p" "IPR018280:Ribosomal protein S3, conserved site, IPR001351:Ribosomal protein S3, C-terminal, IPR004044:K Homology domain, type 2, IPR005703:Ribosomal protein S3, eukaryotic/archaeal, IPR009019:K homology domain, prokaryotic type, IPR015946:K homology domain-like, alpha/beta" CG6779 11-Aug-17 DroID_v2017_08 Drer\rps3 Scer\RPS3 Cele\rps-3 Xtro\rps3 Mmus\Rps3 Hsap\RPS3 "lethal,recessive,visible,dominant,female fertile,reduced,Minute,size defective,viable,male sterile,female sterile,cell lethal,developmental rate defective,fertile,small body" "scutellar bristle,macrochaeta,adult heart,eye-antennal disc,wing disc,male genitalia,testis,primary spermatocyte cyst,germarium,egg chamber,ovariole,eye" DRSC16838 EK -1.457786632 0.186830685 -0.64497703 -3.473035645 0.796679579 3.822449427 FBgn0003255 rk rickets http://flybase.org/reports/FBgn0003255 - protein_coding_gene "protein-hormone receptor activity ; GO:0016500 | inferred from electronic annotation with InterPro:IPR002131 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from physical interaction with Burs, Pburs neuropeptide receptor activity ; GO:0008188 | inferred from sequence model protein-hormone receptor activity ; GO:0016500 | inferred from sequence or structural similarity" G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model regulation of chitin-based cuticle tanning ; GO:0007564 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype border follicle cell delamination ; GO:0030709 | inferred from mutant phenotype intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype epithelial to mesenchymal transition ; GO:0001837 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG8930, rk, Lgr2, DLGR2, LGR2, DLGR-2, rk/CG8930, CT25644, BG:DS00180.13, lgr2, rickets" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001611:Leucine-rich repeat, IPR002131:Glycoprotein hormone receptor family, IPR003591:Leucine-rich repeat, typical subtype, IPR017452:GPCR, rhodopsin-like, 7TM, IPR032675:Leucine-rich repeat domain, L domain-like, IPR034298:TSH/LHCG/FSH receptor" CG8930 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-52j6.3, Drer\lrrc53, Drer\LOC101882074, Drer\lgr4, Drer\rxfp2b, Drer\lrit1a, Drer\rxfp1, Drer\tshr, Drer\drc3, Drer\lhcgr, Drer\lrit1b, Drer\LOC100330212, Drer\lrit3b, Drer\fshr, Drer\lrit3a, Drer\rxfp2l, Drer\rxfp2a" - "Cele\lron-9, Cele\fshr-1, Cele\pan-1" "Xtro\drc3, Xtro\rxfp2, Xtro\tshr, Xtro\rxfp1, Xtro\lgr5, Xtro\fshr" "Mmus\Tshr, Mmus\Lrg1, Mmus\Tril, Mmus\Fshr, Mmus\Lrrc48, Mmus\Lrit3, Mmus\Lgr6, Mmus\Rxfp2, Mmus\Lrit1, Mmus\Lhcgr, Mmus\Chadl, Mmus\Lgr4, Mmus\Cpn2, Mmus\Lrrc26, Mmus\Lgr5, Mmus\Rxfp1, Mmus\Lrrc52" "Hsap\FSHR, Hsap\LRIT1, Hsap\LGR6, Hsap\LRRC26, Hsap\RXFP2, Hsap\CPN2, Hsap\LRG1, Hsap\LGR4, Hsap\LRIT3, Hsap\LHCGR, Hsap\LRRC52, Hsap\RXFP1, Hsap\DRC3, Hsap\LGR5, Hsap\TSHR, Hsap\CHADL, Hsap\TRIL" " embryonic stage , pupal stage " "lethal - all die before end of embryonic stage,recessive,visible,viable,fertile,some die during embryonic stage,decreased cell death,partially lethal - majority die,mating defective,male,reduced,behavior defective,developmental rate defective,small body,body color defective,lethal,heat sensitive,lethal - all die before end of P-stage,some die during pharate adult stage,locomotor behavior defective" "wing,leg,tarsal segment,adult cuticle,neurosecretory neuron,metathoracic leg,macrochaeta,posterior scutellar bristle,heat sensitive,abdomen,haltere,pupal cuticle,metathoracic tarsal segment,mesothoracic tergum" FBgn0002552 lin lines http://flybase.org/reports/FBgn0002552 FBgn0033346 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VQS6 "torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype embryonic foregut morphogenesis ; GO:0048617 | inferred from mutant phenotype foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype epidermis development ; GO:0008544 | inferred from mutant phenotype proximal/distal axis specification ; GO:0009946 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from genetic interaction with tor embryonic hindgut morphogenesis ; GO:0048619 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG11770, Lin, lin" "IPR032794:Protein Lines, N-terminal, IPR024875:Protein Lines, IPR029415:Protein Lines, C-terminal" CG11770 11-Aug-17 DroID_v2017_08 Drer\lins1 - "Cele\T01D1.5, Cele\str-222" Xtro\lins1 Mmus\Lins1 Hsap\LINS1 embryonic stage " inclusive hindgut primordium

, embryonic epidermis

, mesoderm

, stomodeum

" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,lethal,visible,somatic clone,increased cell death,partially lethal - majority die,some die during pupal stage" "denticle row 1,denticle row 2,denticle row 3,denticle row 4,denticle belt,denticle,ectopic,dorsal denticle,embryonic hindgut,dorsal thick hair,dorsal fine hair,embryonic/larval posterior spiracle,embryonic/larval hindgut,embryonic Malpighian tubule,embryonic/larval somatic muscle,dorsal,abdominal segment 8,embryonic foregut,keyhole structure,embryonic dorsal epidermis,embryonic large intestine,embryonic proventriculus,embryonic epidermis,embryonic head,embryonic segment,anterior,embryonic abdominal segment 8,anal plate,primordium of embryonic/larval spiracle,disc epithelium proper & dorsal mesothoracic disc | somatic clone,wing hinge primordium,somatic clone,heart primordium,photoreceptor cell,eye,denticle belt & abdominal segment 8,mouthpart,anal pad,hindgut proper primordium,prothoracic tarsal segment,cell autonomous,antenna,peripodial epithelium & dorsal mesothoracic discptc-559.1,eye disc,peripodial epithelium & dorsal mesothoracic discUbx-lac1-Gal4,adult thorax,peripodial epithelium & dorsal mesothoracic disc | somatic clone,antennal disc,head capsule,prescutum,sex comb,arista,basal cylinder,third segment of antenna,mesothoracic tergum" FBgn0005613 Sox15 Sox box protein 15 http://flybase.org/reports/FBgn0005613 "FBgn0024287, FBgn0040750" protein_coding_gene - "chaeta development ; GO:0022416 | inferred from mutant phenotype inferred from genetic interaction with Su(H) negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype inferred from genetic interaction with wg negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from genetic interaction with Su(H) negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "CG8404, Sox F, SOXF, SOX50E, SOX15, Dsox-15, SoxE, DSox-15, CG13945, Sox50E, Sox15, SoxF" IPR009071:High mobility group box domain CG8404 11-Aug-17 DroID_v2017_08 "Drer\tcf7l1b, Drer\sox18, Drer\lef1, Drer\tcf7, Drer\sox7, Drer\sox17, Drer\tcf7l1a, Drer\sox21b, Drer\sox14, Drer\sox12, Drer\tcf7l2, Drer\sox32" Scer\ROX1 "Cele\sox-2, Cele\sem-2, Cele\sox-3" "Xtro\sox21, Xtro\sox7, Xtro\sox17b.1, Xtro\sox18, Xtro\tcf7l1, Xtro\sox17a, Xtro\sox17b.2, Xtro\sox14, Xtro\tcf7, Xtro\lef1, Xtro\tcf7l2" "Mmus\Lef1, Mmus\Sox14, Mmus\Sox7, Mmus\Sox17, Mmus\Sox21, Mmus\Tcf7l1, Mmus\Tcf7, Mmus\Sox18, Mmus\Sox12" "Hsap\PINX1, Hsap\SOX7, Hsap\SOX17, Hsap\SOX18, Hsap\TCF7L2, Hsap\LEF1, Hsap\SOX21, Hsap\SOX12, Hsap\SOX14, Hsap\TCF7, Hsap\TCF7L1" "visible,locomotor behavior defective,neurophysiology defective,partially lethal - majority die,recessive,size defective,increased cell number,increased cell death,short lived,some die during pupal stage" "wing hinge,joint,mechanosensory chaeta,tormogen cell,eo dendrite,wing sclerite,alula,wing hinge primordium,wing blade,trichogen cell" DRSC07555 K 0.204688004 -0.765390591 -0.915025291 -1.224853626 1.594020322 -0.073472382 FBgn0051525 CG31525 - http://flybase.org/reports/FBgn0051525 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31525 - CG31525 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0069309 X-31-10 X-31-10 http://flybase.org/reports/FBgn0069309 gene molecular_function ; GO:0003674 | no biological data available nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-31-10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,neurogenic phenotype,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" FBgn0039132 AP-1sigma "Adaptor Protein complex 1, sigma subunit" http://flybase.org/reports/FBgn0039132 protein_coding_gene clathrin binding ; GO:0030276 | inferred from sequence or structural similarity with SGD:S000004160 protein transporter activity ; GO:0008565 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR000804 vesicle coating ; GO:0006901 | traceable author statement synaptic vesicle coating ; GO:0016183 | traceable author statement intracellular transport ; GO:0046907 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with SGD:S000004160 axon guidance ; GO:0007411 | inferred from mutant phenotype coated vesicle ; GO:0030135 | traceable author statement AP-1 adaptor complex ; GO:0030121 | inferred from sequence or structural similarity with SGD:S000004160 synaptic vesicle ; GO:0008021 | traceable author statement AP-1 adaptor complex ; GO:0030121 | inferred from mutant phenotype "cg5864, CG5864, sigma1, AP-1[sigma], AP-1sigma, AP-1sigma1, aps1, AP1sigma1" "IPR000804:Clathrin adaptor complex, small chain, IPR011012:Longin-like domain, IPR016635:Adaptor protein complex, sigma subunit, IPR022775:AP complex, mu/sigma subunit" CG5864 11-Aug-17 DroID_v2017_08 "Drer\ap1s3a, Drer\arpin, Drer\ap2s1, Drer\ap1s3b, Drer\ap4s1, Drer\ap1s2, Drer\ap1s1" Scer\APS1 "Cele\aps-3, Cele\aps-2, Cele\aps-1" "Xtro\ap1s1, Xtro\ap1s2, Xtro\ap3s1, Xtro\ap4s1, Xtro\ap1s3, Xtro\arpin, Xtro\ap2s1, Xtro\ap3s2" "Mmus\Ap1s2, Mmus\Arpin, Mmus\Ap1s1, Mmus\Ap1s3, Mmus\Ap2s1, Mmus\Ap3s1, Mmus\Ap3s2, Mmus\Ap4s1" "Hsap\AP1S1, Hsap\AP4S1, Hsap\ARPIN, Hsap\AP3S1, Hsap\AP2S1, Hsap\AP1S3, Hsap\AP1S2" "viable,visible,body color defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum,eye,ommatidium,photoreceptor cell R7,photoreceptor cell R8" FBgn0005012 dipp-3 defective in phototaxis plasticity 3 http://flybase.org/reports/FBgn0005012 - gene - - - dipp-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,visual behavior defective,phototaxis defective" photoreceptor FBgn0084370 C20 C20 http://flybase.org/reports/FBgn0084370 gene - - - C20 - - 11-Aug-17 DroID_v2017_08 - - - - - - eye color defective pigment cell FBgn0020388 Gcn5 Gcn5 acetyltransferase http://flybase.org/reports/FBgn0020388 FBgn0046345 protein_coding_gene H4 histone acetyltransferase activity ; GO:0010485 | inferred from direct assay H3 histone acetyltransferase activity ; GO:0010484 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KSD8 inferred from physical interaction with UniProtKB:Q8I8V0 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone acetyltransferase activity ; GO:0004402 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR009464, InterPro:IPR016376 histone H4 acetylation ; GO:0043967 | inferred from direct assay axon target recognition ; GO:0007412 | inferred from mutant phenotype histone H3 acetylation ; GO:0043966 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay muscle organ development ; GO:0007517 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from direct assay" Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "dGCN5, dGcn5, dmGCN5, GCN5, PCAF, Gcn5, P/CAF, dmHAG401, gcn5, CG4107, Gcn5/PCAF, dGCN5 HAT, p/CAF, dPCAF, anon-WO0172774.89, Gcn5/Pcaf, Pcaf, Ada4, dKAT2, KAT, dGcn5i, KAT2, pCAF" "IPR018359:Bromodomain, conserved site, IPR000182:GNAT domain, IPR001487:Bromodomain, IPR009464:PCAF, N-terminal, IPR016181:Acyl-CoA N-acyltransferase, IPR016376:Histone acetyltransferase GCN5/PCAF" CG4107 11-Aug-17 DroID_v2017_08 "Drer\kat2a, Drer\kat2b, Drer\cecr2" "Scer\GCN5, Scer\SPT7" Cele\pcaf-1 "Xtro\kat2a, Xtro\kat2b, Xtro\cecr2" "Mmus\Kat2b, Mmus\Kat2a, Mmus\Cecr2" "Hsap\KAT2B, Hsap\KAT2A, Hsap\CECR2" embryonic stage -- adult stage "lethal,partially lethal - majority die,some die during pharate adult stage,viable,visible,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of larval stage,some die during larval stage" "metathoracic leg,wing,eye,ommatidium,adult cuticle & adult abdomen,cuticle & abdomen & pharate adult,femur,trichogen cell,wing disc,posterior compartment,wing vein,tarsal segment,wing margin,cuticle & abdomen & pharate adultesg-NP5153,ovary,stage S5 oocyte,stage S6 oocyte,prepupa,polytene chromosome puff | wandering third instar larval stage,imaginal disc,eye photoreceptor cell,intestinal stem cell" DRSC26932 K -0.073088845 0.437495193 -1.089664747 0.105412039 1.710966674 1.922924509 FBgn0000674 flo fiber loop http://flybase.org/reports/FBgn0000674 - gene - - - "flo[N115], flo" - - 11-Aug-17 DroID_v2017_08 - - - - - - axon & optic lobe FBgn0020840 l(2)CA61 lethal (2) CA61 http://flybase.org/reports/FBgn0020840 - gene - - - l(2)CA61 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003346 RanGAP Ran GTPase activating protein http://flybase.org/reports/FBgn0003346 - protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from direct assay signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR009109 positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay meiotic chromosome segregation ; GO:0045132 | traceable author statement nucleocytoplasmic transport ; GO:0006913 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype protein export from nucleus ; GO:0006611 | inferred from mutant phenotype nucleocytoplasmic transport ; GO:0006913 | non-traceable author statement perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "Sd, SD, dRanGAP, rangap, CG9999, RanGAP, ranGAP, Scl, CT28175, Rangap, Sd-RanGAP, Ran, Sd-RanGap, RanGap1, ranGap, RanGap, RGP1_DROME" "IPR009109:Ran-GTPase activating protein 1, C-terminal, IPR027038:Ran GTPase-activating protein, IPR001611:Leucine-rich repeat" CG9999 11-Aug-17 DroID_v2017_08 "Drer\rangap1a, Drer\rangap1b" Scer\RNA1 Cele\ran-2 Xtro\rangap1 Mmus\Rangap1 Hsap\RANGAP1 " adult stage , pupal stage " " adult stage | male , embryonic stage , adult stage , larval stage " " testis

, larval salivary gland

" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,meiotic cell cycle defective,dominant" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,spermatid,embryonic/larval salivary gland" DRSC22003 K 0.748988278 0.123681811 0.059167357 1.145165847 1.516206825 0.165668162 FBgn0015600 toc toucan http://flybase.org/reports/FBgn0015600 "FBgn0010486, FBgn0063149" protein_coding_gene - syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay spindle pole ; GO:0000922 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "l(2)K08224, l(2)k08224, l(2)05527, l(2)01361, CG9660, BcDNA:LD27161, BA34, toc, Toc" - CG9660 11-Aug-17 DroID_v2017_08 Drer\mtus2a - - - Mmus\Mtus2 Hsap\MTUS2 " adult stage && oogenesis stage | stage S3-8 , embryonic stage | early , adult stage , adult stage && oogenesis stage | late " " oocyte | posterior

, follicle cell | posterior

" "viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female sterile,recessive,mitotic cell cycle defective,lethal,reduced" "spindle pole,spindle,fertilized egg,germline clone,dorsal appendage,egg,egg chamber,interfollicle cell,follicle cell,germarium,nurse follicle cell,spindlemat.‘±Tub67C.THsimVP16,spindle polemat.‘±Tub67C.THsimVP16,nuclear chromosomemat.‘±Tub67C.THsimVP16,spindle microtubulemat.‘±Tub67C.THsimVP16,kinetochore microtubulemat.‘±Tub67C.THsimVP16" DRSC00169 K 0.174891936 0.116633383 -0.132749219 0.854268538 0.835230738 1.988998114 FBgn0040341 CG11664 - http://flybase.org/reports/FBgn0040341 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular space ; GO:0005615 | inferred from sequence model "SP193, EG:BACR7A4.3, CG11664" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG11664 11-Aug-17 DroID_v2017_08 Drer\LOC560023 - "Cele\try-10, Cele\try-5, Cele\try-4, Cele\svh-1, Cele\T22A3.6" - Mmus\Try5 Hsap\PRSS3 viable FBgn0003608 Su(var)206 Suppressor of variegation 206 http://flybase.org/reports/FBgn0003608 - gene - - - "Su(var)206, 206" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0040283 SMC1 Structural maintenance of chromosomes 1 http://flybase.org/reports/FBgn0040283 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR010935 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with HGNC:11111 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with HGNC:11111 chromatin binding ; GO:0003682 | inferred from direct assay mitotic sister chromatid cohesion ; GO:0007064 | inferred from electronic annotation with InterPro:IPR029683 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR029683 mushroom body development ; GO:0016319 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from genetic interaction with ct neuron remodeling ; GO:0016322 | inferred from mutant phenotype cohesin complex ; GO:0008278 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay cohesin complex ; GO:0008278 | non-traceable author statement transcriptionally active chromatin ; GO:0035327 | inferred from direct assay chromosome ; GO:0005694 | colocalizes_with inferred from direct assay "DmSMC1, CG6057, SMC1, Smc1, AAF56231, smc1, dSMC1" "IPR003395:RecF/RecN/SMC, N-terminal, IPR010935:SMCs flexible hinge, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024704:Structural maintenance of chromosomes protein, IPR029683:Structural maintenance of chromosomes protein 1A, metazoan" CG6057 11-Aug-17 DroID_v2017_08 "Drer\smc1al, Drer\smc1a, Drer\smc1b" "Scer\YEL043W, Scer\SMC1" Cele\him-1 "Xtro\smc1b, Xtro\smc1a" "Mmus\Smc1b, Mmus\Smc1a" "Hsap\SMC1A, Hsap\SMC1B" "neuroanatomy defective,somatic clone,lethal,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,viable,fertile,visible,planar polarity defective" "mushroom body gamma-lobe,somatic clone,adult antennal lobe projection neuron VA3 adPN,antennal lobe projection neuron adPN,antennal lobe projection neuron lPN,antennal lobe projection neuron vPN,adult mushroom body,condensed chromosome,mesothoracic tergum,wing hair" DRSC16846 K -0.326822007 1.259834194 -0.551732022 0.475591937 0.885983003 1.701964689 FBgn0004368 Ptp4E Protein tyrosine phosphatase 4E http://flybase.org/reports/FBgn0004368 - protein_coding_gene transmembrane receptor protein tyrosine phosphatase activity ; GO:0005001 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with SGD:S000002389 "central nervous system development ; GO:0007417 | inferred from genetic interaction with Ptp10D protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity protein dephosphorylation ; GO:0006470 | non-traceable author statement motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Ptp10D, Ptp69D inferred from genetic interaction with Ptp10D, Ptp52F protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002389 open tracheal system development ; GO:0007424 | inferred from genetic interaction with Ptp10D" axon ; GO:0030424 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity neuronal cell body ; GO:0043025 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "PTP4E, CG6899, CT21187, R-PTP 4E, DPTP4E, Ptp4E, PtP4E, 4E" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR003961:Fibronectin type III, IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR013783:Immunoglobulin-like fold, IPR003595:Protein-tyrosine phosphatase, catalytic" CG6899 11-Aug-17 DroID_v2017_08 "Drer\LOC100535694, Drer\ptprb, Drer\ptprjb.1, Drer\slc35c2, Drer\ptprh, Drer\LOC101885876, Drer\ptprjb.2, Drer\col7a1l, Drer\ptprz1b, Drer\ptprja, Drer\ptprfb, Drer\ptpro, Drer\ptprq" "Scer\PTP2, Scer\PTP1, Scer\PTP3" "Cele\K07F5.6, Cele\ptp-3, Cele\M05B5.1, Cele\C18E9.7, Cele\dep-1" "Xtro\ptprb, Xtro\ptprq, Xtro\ptpro, Xtro\col14a1, Xtro\igdcc4" "Mmus\Ptprd, Mmus\Ptprz1, Mmus\Ptprs, Mmus\Ptprb, Mmus\Ptprj, Mmus\Ptprf, Mmus\Ptpro, Mmus\Ptprh, Mmus\Ptprq, Mmus\Col20a1" "Hsap\PTPRD, Hsap\PTPRZ1, Hsap\PTPRJ, Hsap\PTPRO, Hsap\COL20A1, Hsap\PTPN7, Hsap\PTPRH, Hsap\PTPRB, Hsap\PTPRS, Hsap\PTPRF, Hsap\PTPRQ, Hsap\TNXB" "viable,partially lethal - majority die,some die during pupal stage,fertile,neuroanatomy defective" ventral nerve cord FBgn0003612 Su(var)2-10 Suppressor of variegation 2-10 http://flybase.org/reports/FBgn0003612 FBgn0010550 protein_coding_gene SUMO transferase activity ; GO:0019789 | inferred from electronic annotation with InterPro:IPR027226 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181 DNA binding ; GO:0003677 | inferred from sequence or structural similarity chromosome condensation ; GO:0030261 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement chromosome organization ; GO:0051276 | traceable author statement imaginal disc growth ; GO:0007446 | traceable author statement negative regulation of JAK-STAT cascade ; GO:0046426 | non-traceable author statement chromosome organization ; GO:0051276 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | traceable author statement hemopoiesis ; GO:0030097 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype regulation of protein catabolic process ; GO:0042176 | traceable author statement double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype "nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay" "dPIAS, ZimpB, Su(Var)2-10, zimp, DPIAS, PIAS, i184, CG8068, dpias, ZimpA, Dpias, l(2)03697, CLOT2057, Suvar(2)10, Su-var(2)10, Su(var)2-10, ZIMP, pias, Su(var)-10, SU(VAR)2-10, DmPias" "IPR003034:SAP domain, IPR004181:Zinc finger, MIZ-type, IPR023321:PINIT domain, IPR027226:E3 SUMO-protein ligase PIAS3, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8068 11-Aug-17 DroID_v2017_08 "Drer\pias2, Drer\pias1a, Drer\zmiz1a, Drer\pias1b, Drer\zmiz2, Drer\pias4b, Drer\pias4a" "Scer\NFI1, Scer\SIZ1" "Cele\gei-17, Cele\miz-1" "Xtro\pias4, Xtro\pias3, Xtro\zmiz1, Xtro\pias2, Xtro\pias1, Xtro\zmiz2" "Mmus\Pias4, Mmus\Zmiz2, Mmus\Pias2, Mmus\Pias1, Mmus\Pias3, Mmus\Zmiz1" "Hsap\PIAS2, Hsap\ZMIZ1, Hsap\ZMIZ2, Hsap\PIAS1, Hsap\PIAS4, Hsap\PIAS3" " embryonic stage , embryonic stage | early , embryonic stage && adult stage , adult stage && oogenesis stage | stage >=S10 " "

ubiquitous , egg chamber

" "viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,melanotic mass phenotype,mitotic cell cycle defective,meiotic cell cycle defective,dominant,suppressor of variegation,visible,wild-type,immune response defective,conditional,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "lens,somatic clone,eye,ommatidium,photoreceptor cell,polytene chromosome2-102),polytene chromosome2-101),interphase & nuclear chromosome2-101),polytene chromosome2-10Pex74a),border follicle cell,interphase & nuclear chromosome2-102),adult gut,embryonic/larval neuroblast,ganglion mother cell" DRSC07721 K 0.305912607 -0.833541624 0.479179244 -0.784448279 1.629817576 0.362200045 FBgn0013765 cnn centrosomin http://flybase.org/reports/FBgn0013765 "FBgn0002675, FBgn0020264, FBgn0033839" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sas-4 protein binding ; GO:0005515 | inferred from physical interaction with Cen microtubule binding ; GO:0008017 | inferred from sequence or structural similarity asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype regulation of centriole-centriole cohesion ; GO:0030997 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from direct assay centrosome cycle ; GO:0007098 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from direct assay midgut development ; GO:0007494 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype embryonic cleavage ; GO:0040016 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype pericentriolar material ; GO:0000242 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay pericentriolar material ; GO:0000242 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity spindle pole ; GO:0000922 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay "cnn, Cnn, CNN, CG4832, obv, mat(2)syn-C, mat(2)synHK21, mfs, CG18370, CG 4832, cen, Cnn1" "IPR012943:Centrosomin, N-terminal motif 1" CG4832 11-Aug-17 DroID_v2017_08 "Drer\sptbn1, Drer\si:ch211-242b18.1, Drer\triob, Drer\zgc:55582" Scer\SLK19 "Cele\hcp-1, Cele\C18C4.5" "Xtro\sptan1, Xtro\sptbn2, Xtro\sptbn5, Xtro\pde4dip" "Mmus\Sptan1, Mmus\Pde4dip, Mmus\Cdk5rap2" "Hsap\CDK5RAP2, Hsap\LOC653513, Hsap\PDE4DIP" " embryonic stage | stage 10 , embryonic stage | stage 14 , embryonic stage | early , embryonic stage | stage 6,7 , embryonic stage | stage 5 , embryonic stage | stage 11 , adult stage | male , embryonic stage | stage 11-16 , adult stage | female " " neuroblast

, brain

, ventral furrow

, central nervous system

, peripheral nervous system

, cephalic furrow

, testis

, visceral mesoderm | restricted

, ovary

" " embryonic stage | stage 14-16 , embryonic stage | stage 6,7 , embryonic stage | stage 11 , embryonic stage | stage 5 , adult stage && oogenesis stage , adult stage | male , embryonic stage | stage 14 , embryonic stage | stage 4 , spermatogenesis && adult stage , embryonic stage , embryonic stage | stage 10 " " visceral mesoderm &&of midgut constriction 2

, ventral furrow

, peripheral nervous system

, ovary

, visceral mesoderm &&of gastric caecum

, spermatocyte

, testis

, brain

,

, central nervous system

, cephalic furrow

, neuroblast

, spermatogonium

" "viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal,male sterile,meiotic cell cycle defective,dominant,male fertile,wild-type,female sterile,recessive,mitotic cell cycle defective,cytokinesis defective,male,cell cycle defective,non-suppressor of variegation,partially lethal - majority die,some die during pupal stage" "centriole,centrosomenos.UTR.THsimVP16,centriolar satellitenos.UTR.THsimVP16,centrosome | embryonic stage 4,pericentriolar material | embryonic stage 4,spindle | embryonic stage 4,embryonic cortex & actin filament,embryo,centrosome,spindle,mitotic cell cycle,spindle microtubule,maternal effect,nucleus | embryonic stage | maternal effect,nuclear chromosome | embryonic stage | maternal effect,spindle | embryonic stage | maternal effect,meiotic cell cycle | male,meiosis I & aster,spermatocyte,spermatid,male germline stem cell,supernumerary,cyst progenitor cell,cleavage furrow | embryonic stage,spindle | embryonic stage,pole cell,wing,neuroblast,male germline stem cell & spindle,male germline stem cell & centrosome,centrosome & male germline stem cell,somatic clone,ganglion mother cell,axoneme,spermatocyte & spindle,astral microtubule" DRSC07596 E 0.662958831 0.383168078 -0.308911937 2.657951947 0.045307453 -0.166702686 FBgn0025743 mbt mushroom bodies tiny http://flybase.org/reports/FBgn0025743 "FBgn0025244, FBgn0026024, FBgn0044827" protein_coding_gene receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement ATP binding ; GO:0005524 | inferred from mutant phenotype receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40793 Rho GTPase binding ; GO:0017048 | inferred from physical interaction with Cdc42 protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein kinase activity ; GO:0004672 | inferred from direct assay compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype regulation of cell-cell adhesion mediated by cadherin ; GO:2000047 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype positive regulation of compound eye photoreceptor development ; GO:0045315 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from direct assay activation of MAPK activity ; GO:0000187 | traceable author statement mushroom body development ; GO:0016319 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | traceable author statement plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay cell-cell adherens junction ; GO:0005913 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "DmPAK2, DmMBT, Mbt, CG18582, STE20, Ste20, dPAK2, anon-EST:fe1G7, Pak2, mbt, PAK" "IPR000095:CRIB domain, IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR033923:p21 activated kinase binding domain" CG18582 11-Aug-17 DroID_v2017_08 "Drer\zgc:172180, Drer\LOC100536197, Drer\pak4, Drer\pak6b, Drer\pak7, Drer\pak1, Drer\pak2a" "Scer\SKM1, Scer\STE20, Scer\CLA4" Cele\pak-2 "Xtro\pak3, Xtro\pak4, Xtro\pak7, Xtro\pak2, Xtro\pak1, Xtro\pak6" "Mmus\Pak7, Mmus\Pak4, Mmus\Pak6, Mmus\Pak2, Mmus\Pak3, Mmus\Samd4b, Mmus\Pak1" "Hsap\PAK6, Hsap\BUB1B-PAK6, Hsap\PAK1, Hsap\PAK3, Hsap\PAK5, Hsap\PAK4, Hsap\PAK2" "viable,visible,recessive,fertile,body color defective,partially lethal - majority die,some die during pupal stage" "rhabdomere & eye photoreceptor cell,eye,ommatidium,eye photoreceptor cell,rhabdomere & eye photoreceptor cellelav.PLu,nucleus & eye photoreceptor cell | third instar larval stageelav.PLu,filamentous actin & eye photoreceptor cell | third instar larval stageelav.PLu,ommatidial precursor cluster | third instar larval stage,ommatidium | pupal stage P7,filamentous actin & ommatidium | pupal stage P7elav.PLu,cone cell | pupal stage P7,interommatidial bristle | pupal stage P7,pigment cell & retina | pupal stage P7elav.PLu,Kenyon cell,macrochaeta,lobe system of adult mushroom body,adult mushroom body,calyx of adult mushroom body,mushroom body & neuroblast,rhabdomere,ommatidial precursor cluster,interommatidial bristle,cone cell,supernumerary,adherens junction & ommatidium | pupal stage P7elav.PLu,chaeta,mesothoracic tergum" FBgn0002938 ninaC neither inactivation nor afterpotential C http://flybase.org/reports/FBgn0002938 "FBgn0026796, FBgn0026835" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001609, InterPro:IPR002290 motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609 protein tyrosine kinase activity ; GO:0004713 | inferred from electronic annotation with InterPro:IPR020635 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity calmodulin binding ; GO:0005516 | inferred from mutant phenotype receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement calmodulin binding ; GO:0005516 | traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity phosphatidylinositol binding ; GO:0035091 | inferred from direct assay ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR002290, InterPro:IPR008266 photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype adaptation of rhodopsin mediated signaling ; GO:0016062 | inferred from mutant phenotype protein localization ; GO:0008104 | traceable author statement dsRNA transport ; GO:0033227 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from mutant phenotype phototransduction, UV ; GO:0007604 | inferred from mutant phenotype protein localization to rhabdomere ; GO:1990146 | inferred from mutant phenotype adaptation of rhodopsin mediated signaling ; GO:0016062 | traceable author statement inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | traceable author statement deactivation of rhodopsin mediated signaling ; GO:0016059 | traceable author statement inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype adaptation of rhodopsin mediated signaling ; GO:0016062 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement" myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609 rhabdomere ; GO:0016028 | inferred from direct assay myosin complex ; GO:0016459 | inferred from sequence or structural similarity unconventional myosin complex ; GO:0016461 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay myosin III complex ; GO:0042385 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay inaD signaling complex ; GO:0016027 | traceable author statement inaD signaling complex ; GO:0016027 | inferred from physical interaction with inaD "Nina C, NINAC, NinaC, Dm NinaC, CG5125, NINA C, CT42491, CT16120, CG54125, 2.2, DRONINAC, ninaC, ninac, CG 5125, Myo1B" "IPR000048:IQ motif, EF-hand binding site, IPR000719:Protein kinase domain, IPR001609:Myosin head, motor domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR020635:Tyrosine-protein kinase, catalytic domain" CG5125 11-Aug-17 DroID_v2017_08 "Drer\myo3a, Drer\myo9aa, Drer\myo15aa, Drer\si:ch73-194h10.2, Drer\myo10l3, Drer\myo3b, Drer\myo7bb, Drer\tnika, Drer\myo7aa, Drer\myo9ab, Drer\myo10l1, Drer\myo15b, Drer\myo15ab, Drer\tnikb, Drer\LOC556989, Drer\myo9b, Drer\mink1, Drer\myo7ab, Drer\si:zfos-2326c3.2" Scer\MYO2 Cele\mig-15 "Xtro\tnik, Xtro\kit, Xtro\LOC100494069, Xtro\myo10, Xtro\myo9a, Xtro\myo7a, Xtro\myo3b, Xtro\nrk, Xtro\myo3a, Xtro\sptbn1, Xtro\myo10.2, Xtro\LOC100489062" "Mmus\Myo3a, Mmus\Tnik, Mmus\Nrk, Mmus\Myo15, Mmus\Map4k4, Mmus\Myo9a, Mmus\Myo7b, Mmus\Mink1, Mmus\Myo9b, Mmus\Myo10, Mmus\Myo3b, Mmus\Myo7a" "Hsap\MYO3A, Hsap\MYO3B, Hsap\MYO7B, Hsap\MYO9A, Hsap\MYO15A, Hsap\MAP4K4, Hsap\MYO7A, Hsap\TNIK, Hsap\MINK1, Hsap\MYO10, Hsap\MAP4K3, Hsap\MYO9B, Hsap\MAP4K5" adult stage head

adult stage " rhabdomere

, ocellus rhabdomere

, adult head

" "neurophysiology defective,visual behavior defective,wild-type,behavior defective,recessive,phototaxis defective,viable" "eye photoreceptor cell,eye,retina,photoreceptor cell,ommatidium,rhabdomere,male genitalia" FBgn0011591 fng fringe http://flybase.org/reports/FBgn0011591 FBgn0011797 protein_coding_gene O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity ; GO:0033829 | inferred from direct assay acetylglucosaminyltransferase activity ; GO:0008375 | inferred from direct assay acetylglucosaminyltransferase activity ; GO:0008375 | traceable author statement UDP-glycosyltransferase activity ; GO:0008194 | inferred from direct assay "compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | non-traceable author statement germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | traceable author statement cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from direct assay negative regulation of Notch signaling pathway ; GO:0045746 | non-traceable author statement oogenesis ; GO:0048477 | traceable author statement regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype cell fate specification ; GO:0001708 | non-traceable author statement dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | inferred from direct assay Notch signaling pathway ; GO:0007219 | inferred from direct assay wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap Notch signaling pathway ; GO:0007219 | traceable author statement fucose metabolic process ; GO:0006004 | inferred from direct assay female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from direct assay imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype protein O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype fucose metabolic process ; GO:0006004 | inferred from mutant phenotype" integral component of Golgi membrane ; GO:0030173 | inferred from electronic annotation with InterPro:IPR017374 Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi medial cisterna ; GO:0005797 | inferred from direct assay Golgi apparatus ; GO:0005794 | traceable author statement Golgi stack ; GO:0005795 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "fng, Dfng, CG10580, D-Fng, l(3)rG554, frg, fg, Frg, D-fng, Fng, fringe" "IPR017374:Fringe, IPR003378:Fringe-like" CG10580 11-Aug-17 DroID_v2017_08 "Drer\mfng, Drer\lfng, Drer\rfng" "Scer\YHR210C, Scer\YNR071C" "Cele\ZC250.2, Cele\Y19D10A.16, Cele\C01B4.6" "Xtro\lfng, Xtro\rfng" "Mmus\Rfng, Mmus\Mfng, Mmus\Lfng" "Hsap\RFNG, Hsap\MFNG, Hsap\LFNG" " adult stage && oogenesis stage | stage S2-4 , larval stage | second instar , larval stage | third instar , adult stage && oogenesis stage | stage S5 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S6-9 , adult stage && oogenesis stage | stage S10 " " polar follicle cell

, dorsal mesothoracic disc | dorsal

, dorsal mesothoracic disc | restricted

, follicle cell

, follicle cell &&of germarium region 2b

, follicle cell | subset

" "partially lethal - majority live,lethal,recessive,visible,planar polarity defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,dominant,cell non-autonomous,somatic clone,viable,cell shape defective,partially,decreased cell number" "wing,femur,somatic clone,tibia,wing vein L4,eye,ovary,interfollicle cell,follicle cell,denticle,ectopic,wing vein,ommatidium,photoreceptor,heat sensitive,egg chamber,dorsal appendage,egg,wing margin,anterior/posterior compartment boundary,trochanter,proventriculus inner layer primordium,proventriculus intermediate layer primordium,proventriculus outer layer primordium,embryonic proventriculus,keyhole structure,ocellar triangle,cell non-autonomous,eye equator,ventral,coxa,joint,cell autonomous,metatarsus,tarsal segment 2,tarsal segment 3,tarsal segment 4,antenna,maternal effect,wing disc,polar follicle cell,border follicle cell,nurse follicle cell,centripetally migrating follicle cell,oocyte,dorsal,filamentous actin & denticle field primordium,denticle row,pretarsus,eye disc,supernumerary,dorsal mesothoracic disc & filamentous actin | anterior/posterior compartment boundaryptc-559.1,wing margin bristle,leg,leg & jointDll-md23,anterior dorsocentral bristle,scutum,germarium cap cell,female germline stem cell" FBgn0010258 Rbp4 RNA-binding protein 4 http://flybase.org/reports/FBgn0010258 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with SGD:S000005483 mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay single-stranded RNA binding ; GO:0003727 | inferred from direct assay mRNA processing ; GO:0006397 | inferred from sequence or structural similarity with SGD:S000005483 cytoplasm ; GO:0005737 | inferred from direct assay "TSR, Tsr, RRM4, rrm4, CG9654, Rbp4, tsr, rbp4" IPR000504:RNA recognition motif domain CG9654 11-Aug-17 DroID_v2017_08 "Drer\eif4ba, Drer\hnrnpa3, Drer\wu:fq32h04, Drer\hnrnpaba, Drer\hnrnpa1b, Drer\hnrnpc, Drer\hnrnpa0l, Drer\dazl, Drer\msi2a, Drer\hnrnpa0b, Drer\raly, Drer\ncoa5, Drer\hnrnpa0a, Drer\hnrnpd, Drer\rbm34, Drer\trnau1apb, Drer\cirbpa, Drer\eif4h, Drer\zcrb1, Drer\hnrnpa1a, Drer\dazap1, Drer\trnau1apa, Drer\srsf10a, Drer\hnrpdl, Drer\msi2b, Drer\hnrnpabb, Drer\zgc:55733" "Scer\NOP12, Scer\NOP6, Scer\HRP1, Scer\NGR1, Scer\NAB6, Scer\CWC2, Scer\NAM8, Scer\MRN1, Scer\MUD1" "Cele\H28G03.1, Cele\msi-1, Cele\hrp-1" "Xtro\rbm34, Xtro\hnrnpa0, Xtro\hnrnpa3, Xtro\dazl, Xtro\hnrnpa1, Xtro\dazap1, Xtro\hnrnpc, Xtro\ralyl, Xtro\eif4b, Xtro\hnrnpab, Xtro\raly, Xtro\trnau1ap, Xtro\hnrnpd, Xtro\eif4h, Xtro\hnrnpa2b1, Xtro\hnrnpdl, Xtro\cirbp, Xtro\msi1" "Mmus\Slirp, Mmus\Tra2b, Mmus\Dazl, Mmus\Eif4h, Mmus\Hnrnpa0, Mmus\Hnrnpa2b1, Mmus\Zcrb1, Mmus\Gm21379, Mmus\Eif4b, Mmus\Rbm31y, Mmus\Hnrnpa1, Mmus\Hnrnpd, Mmus\Raly, Mmus\Trnau1ap, Mmus\Dazap1, Mmus\Srsf10, Mmus\Hnrnpa3, Mmus\Rbm34, Mmus\Hnrnpc, Mmus\Boll, Mmus\Hnrnpdl, Mmus\Srsf12, Mmus\Msi2, Mmus\Hnrnpab, Mmus\Msi1, Mmus\Cirbp" "Hsap\MSI2, Hsap\HNRNPCL1, Hsap\SLIRP, Hsap\HNRNPA1, Hsap\DAZ2, Hsap\DAZAP1, Hsap\RBM34, Hsap\HNRNPA1L2, Hsap\DAZL, Hsap\RBM3, Hsap\DAZ1, Hsap\HNRNPDL, Hsap\SRSF10, Hsap\EIF4H, Hsap\RALY, Hsap\HNRNPA3, Hsap\CIRBP, Hsap\HNRNPAB, Hsap\HNRNPA2B1, Hsap\RALYL, Hsap\BOLL, Hsap\MSI1, Hsap\EIF4B, Hsap\DAZ4, Hsap\TRNAU1AP, Hsap\HNRNPC, Hsap\HNRNPD, Hsap\DAZ3, Hsap\HNRNPA0" " pupal stage , adult stage | male , larval stage | third instar " adult stage | male " spermatid

, spermatocyte

, testis

" "male fertile,partially,female fertile,viable" FBgn0002579 RpL36 Ribosomal protein L36 http://flybase.org/reports/FBgn0002579 "FBgn0025295, FBgn0040151, FBgn0047325" protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000509 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 nucleolus ; GO:0005730 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement nuclear chromosome ; GO:0000228 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "L36a, CG7622, EG:115C2.7, M(1)1B, M(1)Bld, l(1)G0471, l(1)1Bj, anon-EST:Posey274, Vi, BcDNA:AT29875, RpL36, Rpl36, Rp L36" IPR000509:Ribosomal protein L36e CG7622 11-Aug-17 DroID_v2017_08 Drer\rpl36 "Scer\RPL36B, Scer\RPL36A" Cele\rpl-36 Xtro\rpl36 Mmus\Rpl36 Hsap\RPL36 " embryonic stage , adult stage " "lethal,recessive,male sterile,wild-type,viable,reduced,visible,dominant,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" macrochaeta DRSC18708 EK -1.151808359 -0.472142542 4.061574815 -3.220535998 1.694584021 3.04597881 FBgn0030964 Pvf1 PDGF- and VEGF-related factor 1 http://flybase.org/reports/FBgn0030964 protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR000072 vascular endothelial growth factor receptor binding ; GO:0005172 | inferred from sequence or structural similarity with HGNC:12680 heparin binding ; GO:0008201 | inferred from direct assay receptor binding ; GO:0005102 | inferred from sequence or structural similarity with HGNC:12680 inferred from sequence or structural similarity with HGNC:12681 inferred from sequence or structural similarity with HGNC:8799 inferred from sequence or structural similarity with HGNC:8800 inferred from physical interaction with Pvr growth factor receptor binding ; GO:0070851 | inferred from biological aspect of ancestor with PANTHER:PTN000908679 "negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | traceable author statement anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype inferred from genetic interaction with tai Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype vascular endothelial growth factor receptor signaling pathway ; GO:0048010 | inferred from sequence or structural similarity with HGNC:12680 positive regulation of cell proliferation ; GO:0008284 | inferred from biological aspect of ancestor with PANTHER:PTN000908679 regulation of cellular response to X-ray ; GO:2000683 | inferred from mutant phenotype positive regulation of protein autophosphorylation ; GO:0031954 | inferred from biological aspect of ancestor with PANTHER:PTN000908679 hemocyte migration ; GO:0035099 | traceable author statement hemocyte migration ; GO:0035099 | inferred from expression pattern inferred from genetic interaction with Pvf2, Pvf3" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000072 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000908679 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with HGNC:12680 inferred from sequence or structural similarity with HGNC:8799 cytoplasm ; GO:0005737 | inferred from direct assay "vegf1, PVF, PVF1, CG7103, PVFs, pvf1, Vegf17e-b, VEGF2-B, Vegf17e-a, Vegf17E, VEGF, DmVEGF-1, l(1)G0146, EP1624, Pvf1, Pvf, Pvf-1" "IPR000072:PDGF/VEGF domain, IPR029034:Cystine-knot cytokine" CG7103 11-Aug-17 DroID_v2017_08 "Drer\pdgfab, Drer\si:ch211-79m20.1, Drer\vegfc, Drer\pdgfd, Drer\pdgfaa, Drer\pdgfc, Drer\vegfba, Drer\LOC103909601, Drer\vegfab, Drer\figf, Drer\vegfaa, Drer\pdgfbb" - Cele\pvf-1 "Xtro\vegfa, Xtro\vegfc, Xtro\vegfb, Xtro\figf, Xtro\pdgfa, Xtro\pdgfb" "Mmus\Vegfb, Mmus\Pdgfa, Mmus\Vegfa, Mmus\Pdgfc, Mmus\Vegfd, Mmus\Vegfc, Mmus\Pdgfd, Mmus\Pdgfb, Mmus\Pgf" "Hsap\PGF, Hsap\PDGFD, Hsap\PDGFA, Hsap\VEGFD, Hsap\PDGFC, Hsap\VEGFC, Hsap\PDGFB, Hsap\VEGFB, Hsap\VEGFA" " embryonic stage | stage 10-15 , embryonic stage | stage 10-12 , embryonic stage | stage 13 , embryonic stage | stage >12 " " embryonic salivary gland

, posterior ectoderm

restricted , embryonic trachea

, embryonic trachea

restricted , Malpighian tubule

" "viable,reduced,fertile,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,partially lethal - majority die,recessive,wild-type" "border follicle cell,male terminalia,ejaculatory bulb,embryonic dorsal epidermis,intersegmental nerve,anterior fascicle & synapse,embryonic anterior Malpighian tubule,border follicle cell & filopodiumslbo.2.6,somatic clone,adult external abdomen,dorsal,cell non-autonomous" FBgn0038224 ATPsynE "ATP synthase, subunit E" http://flybase.org/reports/FBgn0038224 protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000007255" ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000007255 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P56385 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with UniProtKB:P56385 lipid particle ; GO:0005811 | inferred from direct assay" "c550, anon-88Bd, CG3321, ATPJ, ATPsynE" "IPR008386:ATP synthase, F0 complex, subunit E, mitochondrial" CG3321 11-Aug-17 DroID_v2017_08 "Drer\zgc:171957, Drer\atp5ia, Drer\atp5ib" - Cele\R04F11.2 Xtro\atp5i Mmus\Atp5k Hsap\ATP5I "viable,fertile,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0001311 kkv krotzkopf verkehrt http://flybase.org/reports/FBgn0001311 "FBgn0013580, FBgn0037319, FBgn0043004" protein_coding_gene chitin synthase activity ; GO:0004100 | inferred from sequence or structural similarity with SGD:S000000227 inferred from sequence or structural similarity with SGD:S000000242 inferred from sequence or structural similarity with SGD:S000005136 chitin synthase activity ; GO:0004100 | inferred from biological aspect of ancestor with PANTHER:PTN001115588 "chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype chitin biosynthetic process ; GO:0006031 | inferred from mutant phenotype embryonic epithelial tube formation ; GO:0001838 | inferred from mutant phenotype cuticle chitin biosynthetic process ; GO:0006035 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype response to wounding ; GO:0009611 | inferred from expression pattern adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype cell wall chitin biosynthetic process ; GO:0006038 | inferred from biological aspect of ancestor with PANTHER:PTN001115588" cell septum ; GO:0030428 | inferred from biological aspect of ancestor with PANTHER:PTN001115588 cell periphery ; GO:0071944 | inferred from biological aspect of ancestor with PANTHER:PTN001115588 cytoplasm ; GO:0005737 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity apical part of cell ; GO:0045177 | inferred from direct assay "kkv, CS-1/kkv, blimp, ChSB, DmeChSB, DmCS-1, l(3)82Fh, CS-1, CG2666, Kkv, Blimp, DmeCHS1, chitin synthase" "IPR004835:Chitin synthase, IPR029044:Nucleotide-diphospho-sugar transferases, IPR020846:Major facilitator superfamily domain" CG2666 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-264e16.1, Drer\mpc1, Drer\has2, Drer\si:ch211-219a15.4, Drer\has3, Drer\has1, Drer\chs1, Drer\si:ch211-264e16.2" "Scer\CHS2, Scer\CHS3, Scer\CHS1" "Cele\chs-1, Cele\chs-2" "Xtro\has1, Xtro\has3, Xtro\has2" "Mmus\Has1, Mmus\Has2, Mmus\Has3" "Hsap\HAS3, Hsap\HAS2, Hsap\HAS1" "visible,somatic clone,neuroanatomy defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "cephalopharyngeal skeleton,wing hair,somatic clone,embryonic epidermis,embryonic/first instar larval cuticle,rhabdomere of eye photoreceptor cell,embryo,denticle belt,embryonic/larval tracheal system,Malpighian tubule,ureter,embryonic/larval trachea,cuticle,presumptive embryonic/larval tracheal system,pupal epidermis,embryonic/larval dorsal trunk,dorsal trunk primordium,embryonic/larval dorsal trunk & procuticle,epicuticle,procuticle,hypostomal sclerite,vertical bridge,median tooth,terminal tracheal cell,eye" FBgn0043985 Su(rst)E290 Su(rst)E290 http://flybase.org/reports/FBgn0043985 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E290, Su(rst)E290" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0260365 GSd419 - http://flybase.org/reports/FBgn0260365 gene - - - GSd419 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0001330 kz kurz http://flybase.org/reports/FBgn0001330 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338" RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000433607 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "EG:30B8.2, CG3228, l67, N8, N1, l(1)N4, l(1)2Eb, kz" "IPR001650:Helicase, C-terminal, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011545:DEAD/DEAH box helicase domain" CG3228 11-Aug-17 DroID_v2017_08 Drer\dhx37 Scer\ECM16 Cele\rha-2 Xtro\dhx37 Mmus\Dhx37 Hsap\DHX37 " oogenesis stage && adult stage | female , embryonic stage | 0-6 hr " ovary

"lethal,recessive,wild-type,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0003401 shu shutdown http://flybase.org/reports/FBgn0003401 FBgn0034912 protein_coding_gene FK506 binding ; GO:0005528 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 oogenesis ; GO:0048477 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype Yb body ; GO:0070725 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG4735, shu, Shu" "IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR011990:Tetratricopeptide-like helical domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type" CG4735 11-Aug-17 DroID_v2017_08 "Drer\fkbp10b, Drer\LOC103911693, Drer\fkbp8, Drer\fkbp4, Drer\fkbp16, Drer\fkbp5, Drer\fkbp14, Drer\fkbp7, Drer\fkbp9, Drer\fkbp6, Drer\fkbp10a, Drer\fkbp2" Scer\FPR1 "Cele\fkb-1, Cele\fkb-5, Cele\fkb-6, Cele\fkb-3, Cele\fkb-4" "Xtro\fkbp4, Xtro\fkbp6, Xtro\fkbp8" "Mmus\Fkbp10, Mmus\Fkbp14, Mmus\Fkbp9, Mmus\Fkbp4, Mmus\Fkbp2, Mmus\Fkbp5, Mmus\Fkbp6, Mmus\Fkbp8, Mmus\Fkbp7" "Hsap\FKBP9, Hsap\FKBP14, Hsap\FKBP5, Hsap\FKBP6, Hsap\FKBP7, Hsap\FKBP8, Hsap\FKBP2, Hsap\FKBP4, Hsap\FKBP10" "viable,fertile,wild-type,female sterile,male sterile,recessive" "egg,dorsal appendage,egg chamber,oocyte,germline clone,nurse follicle cell,ovariole,germline cell,female,fusome | femaleb23)" FBgn0041342 Pcyt1 Phosphocholine cytidylyltransferase 1 http://flybase.org/reports/FBgn0041342 protein_coding_gene choline-phosphate cytidylyltransferase activity ; GO:0004105 | inferred from direct assay biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004821 establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype phosphatidylcholine biosynthetic process ; GO:0006656 | inferred by curator from GO:0004105 eye development ; GO:0001654 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CCT1, CT41283, CG1049, cct1, Cct, Cct1, Pcyt1" "IPR004821:Cytidyltransferase-like domain, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG1049 11-Aug-17 DroID_v2017_08 "Drer\pcyt1aa, Drer\pcyt1ab, Drer\pcyt1bb, Drer\pcyt1ba" Scer\PCT1 "Cele\Y18H1A.11, Cele\pcyt-1" "Xtro\pcyt1b, Xtro\pcyt1a" "Mmus\Pcyt1b, Mmus\Pcyt1a" "Hsap\PCYT1A, Hsap\PCYT1B" "viable,partially lethal - majority live,developmental rate defective,planar polarity defective,female sterile,somatic clone,long lived,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,wild-type" "oocyte,egg chamber,germline cyst,ommatidium,eye photoreceptor cell,somatic clone,photoreceptor cell R3,photoreceptor cell R4,egg,maternal effect,fat body,lipid particle,ovariole,nurse cell spectrosome,female germline stem cell,basal stalk,dorsal appendage,egg operculum,germline clone,rhabdomere | larval stage | somatic clone,coated pit,coated vesicle,late endosome | larval stage,crossvein,supernumerary" DRSC08157 I -0.366494648 -1.658417982 -0.36197269 -0.70565282 -0.276655102 -0.387285075 FBgn0021818 cnk connector enhancer of ksr http://flybase.org/reports/FBgn0021818 "FBgn0044753, FBgn0063794" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Raf "imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | non-traceable author statement imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from direct assay anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype Ras protein signal transduction ; GO:0007265 | inferred from genetic interaction with Ras85D inferred from genetic interaction with sev positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D" plasma membrane ; GO:0005886 | inferred from direct assay cell-cell adherens junction ; GO:0005913 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CNK, EK2-3, l(2)k16314, anon-WO0257455.27, anon-WO0140519.129, CG6556, cnk, Cnk, EC2-3" "IPR001478:PDZ domain, IPR001660:Sterile alpha motif domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR013761:Sterile alpha motif/pointed domain, IPR017874:CRIC domain" CG6556 11-Aug-17 DroID_v2017_08 "Drer\cnksr2b, Drer\cnksr1, Drer\cnksr3, Drer\si:ch211-26b3.4, Drer\cnksr2a, Drer\ipcef1" Scer\BOI1 Cele\cnk-1 "Xtro\cnksr2, Xtro\cnksr1, Xtro\cnksr3" "Mmus\Samd3, Mmus\4933403O08Rik, Mmus\Cnksr1, Mmus\Cnksr3, Mmus\Cnksr2, Mmus\Ipcef1" "Hsap\CNKSR1, Hsap\SAMD3, Hsap\CNKSR2, Hsap\CNKSR3, Hsap\IPCEF1" "viable,fertile,neuroanatomy defective,lethal,lethal - all die before end of larval stage,some die during larval stage,visible,recessive,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,wild-type" "synapse,imaginal disc,wing,wing vein,dorsal air sac primordium,somatic clone,eye,wing vein L4,eye photoreceptor cell,photoreceptor cell R7,ectopic,photoreceptor" DRSC07595 IEK -0.022204422 -5.816006724 -0.795623919 -6.929504739 -7.442955435 -5.343142981 FBgn0084745 fang fangorn http://flybase.org/reports/FBgn0084745 gene - "primary branching, open tracheal system ; GO:0007428 | inferred from mutant phenotype" - fang - - 11-Aug-17 DroID_v2017_08 - - - - - - "presumptive embryonic/larval tracheal system,dorsal branch primordium,lateral trunk anterior branch" FBgn0039761 CG18404 - http://flybase.org/reports/FBgn0039761 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "anon-WO0140519.106, CG18404" - CG18404 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0034964 IntS1 Integrator 1 http://flybase.org/reports/FBgn0034964 protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:24555 snRNA 3'-end processing ; GO:0034472 | inferred from direct assay U2 snRNA 3'-end processing ; GO:0034474 | inferred from biological aspect of ancestor with PANTHER:PTN001081376 integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:24555 integrator complex ; GO:0032039 | inferred from biological aspect of ancestor with PANTHER:PTN001081376 "IntS1, CG3173, Int1" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR022145:Domain of unknown function DUF3677" CG3173 11-Aug-17 DroID_v2017_08 Drer\ints1 - Cele\inst-1 Xtro\ints1 Mmus\Ints1 Hsap\INTS1 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC04343 I 0.389503672 -2.503927134 0.560152028 -0.512653638 0.310050932 -0.942329829 FBgn0029068 l(1)G0236 lethal (1) G0236 http://flybase.org/reports/FBgn0029068 gene - - - l(1)G0236 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,lethal" wing FBgn0025730 tbi tibi http://flybase.org/reports/FBgn0025730 - gene - - - tbi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,rescuable maternal effect,visible,recessive" wing FBgn0026058 OdsH Ods-site homeobox http://flybase.org/reports/FBgn0026058 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular space ; GO:0005615 | inferred from direct assay "OdsH[mel], CG6352, OdsH, odsH, odsh, Odsh" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG6352 11-Aug-17 DroID_v2017_08 "Drer\alx3, Drer\alx1, Drer\alx4a, Drer\si:dkey-43p13.5, Drer\uncx4.1, Drer\vsx1, Drer\uncx, Drer\barx1, Drer\prrx1b" - "Cele\unc-4, Cele\dsc-1" "Xtro\alx4, Xtro\prrx1, Xtro\prrx2, Xtro\alx1, Xtro\uncx" "Mmus\Vsx2, Mmus\Alx3, Mmus\Alx1, Mmus\Alx4, Mmus\Prrx2, Mmus\Crxos, Mmus\Prrx1, Mmus\Gm9376, Mmus\Uncx, Mmus\Vsx1" "Hsap\BARX1, Hsap\UNCX, Hsap\ALX4, Hsap\ALX1, Hsap\PRRX1, Hsap\ALX3, Hsap\PRRX2" "viable,male fertile,reduced,male semi-sterile" "male germline stem cell,primary gonial cell,spermatogonium" FBgn0028688 Rpn7 Regulatory particle non-ATPase 7 http://flybase.org/reports/FBgn0028688 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Rpn6 neurogenesis ; GO:0022008 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype "proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9564 inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000006312 proteasome complex ; GO:0000502 | inferred from direct assay" "141231_at, p42A, anon-WO0172774.106, anon-WO0172774.103, CG5378, Rpn7, S10a" "IPR000717:Proteasome component (PCI) domain, IPR019585:26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1, IPR011991:Winged helix-turn-helix DNA-binding domain" CG5378 11-Aug-17 DroID_v2017_08 Drer\psmd6 Scer\RPN7 Cele\rpn-7 Xtro\psmd6 Mmus\Psmd6 Hsap\PSMD6 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC16841 IEK -2.240030176 -4.280276004 -2.423479903 -2.107371086 1.638402825 -1.421385723 FBgn0000910 fs(1)M120 female sterile (1) M120 http://flybase.org/reports/FBgn0000910 - gene - - - fs(1)M120 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0004745 l(3)85Fb lethal (3) 85Fb http://flybase.org/reports/FBgn0004745 - gene - - - l(3)85Fb - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000492 Dr Drop http://flybase.org/reports/FBgn0000492 "FBgn0002849, FBgn0015510, FBgn0020528" protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from sequence or structural similarity with HGNC:7392 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 ectoderm development ; GO:0007398 | traceable author statement glial cell development ; GO:0021782 | inferred from mutant phenotype central nervous system development ; GO:0007417 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of cell fate specification ; GO:0042659 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype wing and notum subfield formation ; GO:0035309 | inferred from mutant phenotype imaginal disc-derived male genitalia development ; GO:0007485 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement pattern specification process ; GO:0007389 | non-traceable author statement muscle organ development ; GO:0007517 | traceable author statement wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype ventral cord development ; GO:0007419 | non-traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype brain development ; GO:0007420 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | inferred from mutant phenotype ventral cord development ; GO:0007419 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "Msh, msh, 153515_at, CG1897, msh1, msh-1, 99B, ltt, l(3)FA30, Dr, Msx, Drop, Dr/msh" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG1897 11-Aug-17 DroID_v2017_08 "Drer\msx1a, Drer\msx3, Drer\msx2b, Drer\msx2a, Drer\msx1b" - "Cele\vab-15, Cele\mls-2, Cele\ceh-16" "Xtro\msx1, Xtro\msx2" "Mmus\Msx1, Mmus\Msx3, Mmus\Msx2" "Hsap\MSX1, Hsap\MSX2" " embryonic stage | stage 11-13 , embryonic stage , embryonic stage | stage 11 , embryonic stage | stage 5-8 , embryonic stage | stage >=11 , embryonic stage | stage 10-12 , larval stage , embryonic stage | stage >=13 , embryonic stage | stage 12-15 , embryonic stage | stage 9-11 , embryonic stage | stage 9-12 , embryonic stage | stage 10,11 , embryonic stage | stage 4 , embryonic stage | stage 8 , embryonic stage -- adult stage , embryonic stage && pupal stage && adult stage " " embryonic/larval fat body

, embryonic/larval hindgut

, neuroblast NB2-4

, lateral ectoderm

, embryonic peripheral nervous system

, neuroblast

, dorsal mesothoracic disc | restricted

, external sensory organ precursor cell

, embryonic/larval foregut

, embryonic central nervous system

, somatic mesoderm

, salivary gland body primordium

, optic lobe | precursor

, ventral nerve cord primordium

, peripheral glial cell | precursor

, embryonic brain | precursor

, neuroblast NB4-3

, neuroblast NB5-4

, dorsal ectoderm

, neuroblast NB3-4

, central nervous system

, neuroblast NB6-4

" embryonic stage | stage 9-11 " ventral neurogenic region && embryonic intercalary segment | dorsal

, tritocerebral neuroblast | subset & dorsal

, procephalic neuroblast | subset & dorsal

, ventral neurogenic region && embryonic antennal segment | dorsal

, deuterocerebral neuroblast | subset & dorsal

" "lethal,neuroanatomy defective,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,uncoordinated,visible,dominant,viable,reduced,increased cell death,locomotor behavior defective,somatic clone,mitotic cell cycle defective,Minute,partially lethal - majority die,wild-type,semidominant,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,behavior defective" "genital disc,ejaculatory duct,male accessory gland,vas deferens,testis,apodeme,hypandrium,clasper long bristle,clasper,genital arch,posterior lobe,lateral plate,cardioblast,pericardial cell,heart primordium,glial cell,embryonic tritocerebrum,basal procephalic longitudinal glia cluster,deutero/tritocerebral embryonic fiber tract founder cluster,macrochaeta,eye,ommatidium,five-cell ommatidial precursor cluster,wing,wing margin,alula,wing vein,medial-most cell body glial cell,medial cell body glial cell,neuroblast,neuron,prothoracic dorsal oblique muscle,mesothoracic dorsal oblique muscle,metathoracic dorsal oblique muscle,abdominal dorsal oblique muscle,mesothoracic lateral transverse muscle,metathoracic lateral transverse muscle,abdominal lateral transverse muscle,metathoracic ventral acute muscle,abdominal ventral acute muscle,wing hinge,wing sclerite,sensillum campaniformium of proximal dorsal radius,scutellum,scutum,chaeta,tegula,presumptive embryonic/larval central nervous system,neuropil associated CNS glial cell,frontal connective,embryonic/larval cervical connective,embryonic/larval tritocerebral commissure,embryonic/larval subesophageal ganglion,segment border muscle,RP2 motor neuron,longitudinal connective,commissure,U neuron,A1-7 ventral longitudinal muscle,A1-7 ventral oblique muscle 1,A1-7 ventral oblique muscle 2,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,mesothoracic dorsal acute muscle 3,metathoracic dorsal acute muscle,abdominal dorsal acute muscle,mesothoracic lateral longitudinal muscle,metathoracic lateral longitudinal muscle 1,abdominal lateral longitudinal muscle,abdominal dorsal transverse muscle,dorsal oblique muscle,dorsal transverse muscle,dorsal acute muscle,,A1-7 dorsal acute muscle 1,A1-7 dorsal oblique muscle 1,hypodermal muscle of larval abdominal 9,ventral midline,aCC neuron,pCC neuron,fpCC neuron,wing sensillum,mesothoracic tergum,morphogenetic furrow,interommatidial bristle,lens,embryonic/larval somatic muscle,trichogen cell" DRSC22708 IEK -0.975651904 -1.698039058 -1.607172171 -4.951681106 0.795958059 1.538469143 FBgn0002945 nkd naked cuticle http://flybase.org/reports/FBgn0002945 "FBgn0036840, FBgn0036841" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from direct assay PDZ domain binding ; GO:0030165 | inferred from physical interaction with dsh neuroblast fate specification ; GO:0014018 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "nkd, Nkd, naked, CG18224, CG11614" IPR015943:WD40/YVTN repeat-like-containing domain CG11614 11-Aug-17 DroID_v2017_08 "Drer\nkd2a, Drer\nkd1, Drer\nkd3, Drer\nkd2b" - - Xtro\nkd1 "Mmus\Nkd1, Mmus\Nkd2" "Hsap\NKD1, Hsap\NKD2" " embryonic stage , larval stage , embryonic stage | early " " ventral thoracic disc

, organism | gap-rule

, imaginal disc

,

segmentally repeated , dorsal mesothoracic disc

" embryonic stage

segmentally repeated "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,somatic clone,wild-type,cell growth defective,planar polarity defective,lethal - all die before end of P-stage,some die during pharate adult stage,viable,fertile" "embryonic/first instar larval cuticle,sternite,denticle belt,cuticle,T1 beard,cephalopharyngeal skeleton,primordium of embryonic/larval spiracle,embryonic head,posterior spiracle primordium,embryonic/larval dorsal vessel,interommatidial bristle,somatic clone,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic gnathal segment,embryonic/larval somatic muscle,neuroblast NB7-3,neuroblast NB6-4,ectopic,embryonic epidermis & embryonic abdominal segment,embryonic epidermis,embryonic/larval spiracle,filzkorper,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic/larval brain,Keilin's organ,abdominal ventral denticle belt,eye,abdominal sternite bristle,leg,wing,scutum,haltere,ventral,wing margin bristle,anterior crossvein,antenna,wing disc,dorsal compartment,wing hair,supernumerary" DRSC11376 K 0.358801754 -0.050080399 0.507997887 -0.31332821 0.511758555 -1.588749481 FBgn0004872 piwi P-element induced wimpy testis http://flybase.org/reports/FBgn0004872 - protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Fmr1 inferred from physical interaction with Dcr-1 inferred from physical interaction with vas "positive regulation of methylation-dependent chromatin silencing ; GO:0090309 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | traceable author statement negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype RNA interference ; GO:0016246 | traceable author statement chromatin silencing ; GO:0006342 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | traceable author statement positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from mutant phenotype gene silencing by RNA ; GO:0031047 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from direct assay heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype male germ-line stem cell asymmetric division ; GO:0048133 | inferred from mutant phenotype negative regulation of transposition, DNA-mediated ; GO:0000335 | inferred from mutant phenotype posttranscriptional gene silencing ; GO:0016441 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from direct assay nucleoplasm ; GO:0005654 | traceable author statement nucleoplasm ; GO:0005654 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay telomeric heterochromatin ; GO:0031933 | inferred from direct assay chromocenter ; GO:0010369 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay Yb body ; GO:0070725 | inferred from physical interaction with armi euchromatin ; GO:0000791 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement "Piwi, piwi, PIWI, CG6122" "IPR003100:PAZ domain, IPR003165:Piwi domain, IPR012337:Ribonuclease H-like domain" CG6122 11-Aug-17 DroID_v2017_08 "Drer\LOC567622, Drer\ago3b, Drer\ago1, Drer\piwil1, Drer\ago2, Drer\piwil2" - "Cele\alg-1, Cele\prg-1, Cele\prg-2, Cele\rde-1, Cele\hpo-24, Cele\alg-3" "Xtro\piwil2, Xtro\piwil3, Xtro\ago4, Xtro\ago3, Xtro\piwil4, Xtro\ago2" "Mmus\Piwil1, Mmus\Ago2, Mmus\Piwil4, Mmus\Ago1, Mmus\Ago3, Mmus\Piwil2, Mmus\Ago4" "Hsap\PIWIL4, Hsap\PIWIL3, Hsap\PIWIL2, Hsap\PIWIL1, Hsap\AGO2, Hsap\AGO4, Hsap\AGO3, Hsap\AGO1" " adult stage && oogenesis stage , embryonic stage | early " " ovary

, germarium region 2b

, terminal filament basal cell

, germarium region 2a

, epithelial sheath

" "female sterile,recessive,male sterile,suppressor of variegation,lethal,non-rescuable maternal effect,mitotic cell cycle defective,germline clone,increased cell death,viable,fertile,non-suppressor of variegation,dominant,enhancer of variegation,wild-type,male fertile" "ovary,testis,ovariole,egg,female germline stem cell,cell autonomous,somatic clone,non-rescuable maternal effect,germarium,germline cyst,cystoblast,embryo,germline clone,embryonic head,syncytial blastoderm embryo,male germline stem cell,pole cell,maternal effect,embryonic/larval cuticle,cephalopharyngeal skeleton,egg chamber,nurse cell spectrosome,ectopic,germline cell,female,spectrosome | ectopichs.PB,spectrosomehs.PB,supernumerary,heat sensitive,dorsal appendage" FBgn0005142 l(2)ff10 lethal (2) ff10 http://flybase.org/reports/FBgn0005142 - gene - - - l(2)ff10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "lens,somatic clone,cone cell,ommatidium" FBgn0035169 CG13890 - http://flybase.org/reports/FBgn0035169 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001753 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR001753 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:14601 inferred from sequence model lipid particle ; GO:0005811 | inferred from direct assay "CG13890, DCI" "IPR001753:Crotonase superfamily, IPR014748:Crontonase, C-terminal, IPR029045:ClpP/crotonase-like domain" CG13890 11-Aug-17 DroID_v2017_08 "Drer\cdyl, Drer\zgc:92030" "Scer\ECI1, Scer\DCI1" "Cele\B0272.4, Cele\ech-4" "Xtro\eci2, Xtro\LOC100490656" "Mmus\Eci3, Mmus\Cdyl2, Mmus\Eci2, Mmus\Cdyl" "Hsap\ECI2, Hsap\CDY1B, Hsap\CDY2B, Hsap\CDYL2, Hsap\CDY2A, Hsap\CDYL, Hsap\CDY1" "viable,fertile,long lived,oxidative stress response defective,starvation stress response defective" FBgn0030703 MSBP membrane steroid binding protein http://flybase.org/reports/FBgn0030703 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000031653 ecdysone binding ; GO:0035100 | inferred from direct assay - plasma membrane ; GO:0005886 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG9066, MSBP, dm_MSBP" IPR001199:Cytochrome b5-like heme/steroid binding domain CG9066 11-Aug-17 DroID_v2017_08 "Drer\pgrmc1, Drer\nenf, Drer\pgrmc2" Scer\DAP1 Cele\vem-1 "Xtro\nenf, Xtro\pgrmc2, Xtro\pgrmc1" "Mmus\Pgrmc1, Mmus\Nenf, Mmus\Pgrmc2" "Hsap\PGRMC2, Hsap\NENF, Hsap\PGRMC1" viable FBgn0025686 Amnionless Amnionless http://flybase.org/reports/FBgn0025686 FBgn0031246 protein_coding_gene - renal protein absorption ; GO:0097017 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype nephrocyte filtration ; GO:0097206 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model "CG11592, CK02467, BEST:CK02467, dAMN, Amnionless, dAmn" IPR026112:Amnionless CG11592 11-Aug-17 DroID_v2017_08 Drer\amn - Cele\Y75B7AL.2 Xtro\amn Mmus\Amn Hsap\AMN "chemical sensitive,viable,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval pericardial cell,chaeta" FBgn0024355 Fab-8 Fab-8 http://flybase.org/reports/FBgn0024355 - insulator - - - "Fab8, Fab-8, PTS" - - 11-Aug-17 DroID_v2017_08 - - - - - - visible eye FBgn0034484 CG11044 - http://flybase.org/reports/FBgn0034484 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG11044, FBXO10" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG11044 11-Aug-17 DroID_v2017_08 Drer\fbxo33 - Cele\K02A6.3 Xtro\fbxo33 "Mmus\Fbxo39, Mmus\Fbxo33" Hsap\FBXO33 "viable,fertile" DRSC06026 E -1.115933391 -0.396187338 -1.541271919 0.301541866 -0.54102196 0.454534871 FBgn0005655 PCNA Proliferating cell nuclear antigen http://flybase.org/reports/FBgn0005655 "FBgn0002895, FBgn0003045, FBgn0004700, FBgn0010513, FBgn0010677" protein_coding_gene "DNA polymerase processivity factor activity ; GO:0030337 | inferred from electronic annotation with InterPro:IPR000730 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000730, InterPro:IPR022648, InterPro:IPR022649" "regulation of DNA replication ; GO:0006275 | inferred from electronic annotation with InterPro:IPR000730, InterPro:IPR022648, InterPro:IPR022649 DNA-dependent DNA replication ; GO:0006261 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | traceable author statement mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype nucleotide-excision repair ; GO:0006289 | traceable author statement antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype mismatch repair ; GO:0006298 | traceable author statement DNA replication ; GO:0006260 | traceable author statement" microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Mus209, DmPCNA, pcna, PCNA/mus209, PCNA, Pcna, l(2)02448, 53/13, l(2)s1534, l(2)56Fa, l(2)56F, CG9193, mus209, dPCNA, MUS209, mus 209, DmPCNA1" "IPR000730:Proliferating cell nuclear antigen, PCNA, IPR022648:Proliferating cell nuclear antigen, PCNA, N-terminal, IPR022649:Proliferating cell nuclear antigen, PCNA, C-terminal, IPR022659:Proliferating cell nuclear antigen, PCNA, conserved site" CG9193 11-Aug-17 DroID_v2017_08 Drer\pcna Scer\POL30 Cele\pcn-1 Xtro\pcna Mmus\Pcna Hsap\PCNA " oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

egg stage | fertilized egg " male pronucleus

, female pronucleus

" "lethal,neuroanatomy defective,endomitotic cell cycle defective,recessive,wild-type,cold sensitive,female sterile,suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,DNA repair defective,female" "embryonic/larval neuroblast,ganglion mother cell,subperineurial glial cell,larval outer optic anlage,mitotic cell cycle,mitotic metaphase,spindle,mitosis & nuclear chromosome,chromosome, centromeric region,macrochaeta,posterior scutellar bristle,nurse cell,ectopic,larval optic anlage,somatic clone,sex comb,prothoracic leg,ovary,ovariole,follicle cell,nucleus | embryonic stage 4" DRSC07653 K -1.086117722 -0.269921659 -1.363834348 -0.752420911 2.665192719 4.660477752 FBgn0060302 ms28E ms28E http://flybase.org/reports/FBgn0060302 gene - - - ms28E - - 11-Aug-17 DroID_v2017_08 - - - - - - spermatid FBgn0013672 mt:ATPase6 mitochondrial ATPase subunit 6 http://flybase.org/reports/FBgn0013672 FBgn0002867 protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000007268 hydrogen-exporting ATPase activity, phosphorylative mechanism ; GO:0008553 | non-traceable author statement proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | inferred from mutant phenotype" determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype mitochondrial ATP synthesis coupled proton transport ; GO:0042776 | inferred by curator from GO:0046933 neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype proton transport ; GO:0015992 | non-traceable author statement ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000007268 "mitochondrion ; GO:0005739 | inferred from mutant phenotype mitochondrion ; GO:0005739 | non-traceable author statement mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with SGD:S000000072" "CG34073, ATPase6, ATP6, mt:ATPase6, mtATP6, atp6, A6, atp6ase" "IPR000568:ATP synthase, F0 complex, subunit A, IPR023011:ATP synthase, F0 complex, subunit A, active site" CG34073 11-Aug-17 DroID_v2017_08 Drer\ATP6 Scer\ATP6 Cele\ATP6 Xtro\ATP6 Mmus\ATP6 "Hsap\ATP8, Hsap\ATP6" "paralytic,short lived,neuroanatomy defective,locomotor behavior defective,bang sensitive,progressive,neurophysiology defective,developmental rate defective,stress response defective" "adult somatic muscle,flight muscle,thoracico-abdominal ganglion,mitochondrial crista,mitochondrial inner membrane" FBgn0013486 l(1)5PP1 lethal (1) 5PP1 http://flybase.org/reports/FBgn0013486 - gene - - - l(1)5PP1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,maternal effect" "embryonic/first instar larval cuticle,germline clone" FBgn0028341 Ptpmeg2 Protein tyrosine phosphatase Meg2 http://flybase.org/reports/FBgn0028341 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with SGD:S000002389 protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002389 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG3101, Ptpmeg2, CG3102, MEG2, CG32697, L(1)G0232, lG0232, l(1)G0232, PTP-Meg2, dMeg2" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR001251:CRAL-TRIO lipid binding domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR011074:CRAL/TRIO, N-terminal domain, IPR029021:Protein-tyrosine phosphatase-like, IPR003595:Protein-tyrosine phosphatase, catalytic" CG32697 11-Aug-17 DroID_v2017_08 "Drer\ptpn9a, Drer\ptpn9b" "Scer\PTP2, Scer\PTP3, Scer\PTP1" "Cele\M01A12.4, Cele\F25H5.7, Cele\T04F3.3, Cele\C46A5.1, Cele\F36H12.10, Cele\H06I04.5, Cele\F20H11.4, Cele\W01B6.6, Cele\W03F11.4, Cele\C15H7.3, Cele\Y39B6A.18, Cele\F55F8.7, Cele\M05D6.3, Cele\T28F4.3, Cele\F47B3.6, Cele\K07F5.8, Cele\Y57G11C.6, Cele\F55H12.5, Cele\Y54F10BM.3, Cele\C24D10.1, Cele\C07E3.4, Cele\F47B3.1, Cele\T22C1.8, Cele\F42C5.5, Cele\F54F12.1, Cele\Y71F9AL.4, Cele\Y39A3A.4, Cele\C33H5.16, Cele\F57H12.5, Cele\Y48G9A.9, Cele\F36H1.3, Cele\egg-3, Cele\ZK354.8, Cele\C02B10.6, Cele\T20B6.1, Cele\M04G7.2, Cele\ZK484.7, Cele\B0207.1, Cele\F35C11.2, Cele\T27A3.5" "Xtro\ptprr, Xtro\ptpn9, Xtro\LOC100489200" Mmus\Ptpn9 "Hsap\PTPRQ, Hsap\PTPN23, Hsap\PTPN9" "viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "eye,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0004876 cdi center divider http://flybase.org/reports/FBgn0004876 FBgn0010912 protein_coding_gene "metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR015782 protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity actin filament organization ; GO:0007015 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement negative regulation of sevenless signaling pathway ; GO:0045873 | inferred from genetic interaction with boss inferred from genetic interaction with sev" apical part of cell ; GO:0045177 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG6027, Cdi, CDI/TSKI, l(3)07013, B9.3, 91F, cdi/TESK1, cdi, Cdi/TESK1" "IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR015782:Dual specificity testis-specific protein kinase 1, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG6027 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113e8.3, Drer\zgc:113162, Drer\tesk2, Drer\si:dkeyp-75h12.2, Drer\zgc:162952" "Scer\PTK1, Scer\PTK2" Cele\Y69E1A.3 - "Mmus\Tesk1, Mmus\Tesk2" "Hsap\TESK1, Hsap\TESK2" "viable,lethal,recessive,fertile,fully,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,body color defective" "photoreceptor cell R7,filamentous actin | somatic clone,intersegmental nerve,anterior fascicle & synapse,macrochaeta,embryonic head,embryonic segment,embryonic/first instar larval cuticle,head,segment,nervous system,actin filament | somatic cloneGMR.PU, mRpL55UAS.cSa,mesothoracic tergum" FBgn0017579 RpL14 Ribosomal protein L14 http://flybase.org/reports/FBgn0017579 "FBgn0025288, FBgn0025308" protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002784 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "M(3)66D, rpl14, CG6253, anon-EST:Posey6, L14, M(3)66, anon-EST:Posey193U, RpL14, M66D, M(3), RPL14, Rp L14" "IPR002784:Ribosomal protein L14e domain, IPR008991:Translation protein SH3-like domain, IPR014722:Ribosomal protein L2 domain 2" CG6253 11-Aug-17 DroID_v2017_08 Drer\rpl14 "Scer\RPL14A, Scer\RPL14B" Cele\rpl-14 Xtro\rpl14 Mmus\Rpl14 Hsap\RPL14 embryonic stage -- adult stage "visible,dominant,lethal,heat sensitive,Minute,some die during immature adult stage,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,developmental rate defective,partially lethal - majority live,cell growth defective,somatic clone,cell non-autonomous" "macrochaeta,chaeta,heat sensitive,anterior scutellar bristle,posterior scutellar bristle,posterior dorsocentral bristle,adult head,eye-antennal disc,thoracico-abdominal ganglion | pharate adult stage,embryonic/larval salivary gland,eye,interommatidial bristle,pigment cell,ommatidium,cornea,pseudocone,leg,wing,wing vein,arista,scutellum,postvertical bristle,microchaeta,wing disc,scutellar bristle" DRSC11269 EK -0.68890909 -0.967008998 0.145064601 -4.900551248 0.662543845 2.842837956 FBgn0034511 GNBP-like3 GNBP-like 3 http://flybase.org/reports/FBgn0034511 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with GNBP3 defense response to other organism ; GO:0098542 | inferred from mutant phenotype detection of biotic stimulus ; GO:0009595 | inferred from sequence or structural similarity with GNBP3 response to fungus ; GO:0009620 | inferred from expression pattern cell surface ; GO:0009986 | inferred from sequence or structural similarity with GNBP3 "GNBP-like, GNBPlike 3, CG13422, GNBP-like3" "IPR031756:Beta-1,3-glucan-binding protein, N-terminal" CG13422 11-Aug-17 DroID_v2017_08 - - Cele\Y53H1B.4 - - - "immune response defective,short lived,conditional,viable" FBgn0005307 ms(1)RA40 male sterile (1) RA40 http://flybase.org/reports/FBgn0005307 - gene - - - ms(1)RA40 - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,meiotic cell cycle defective" "meiotic cell cycle | male,meiotic cell cycle & spindle | male,spermatid" FBgn0021895 ytr yantar http://flybase.org/reports/FBgn0021895 FBgn0034916 protein_coding_gene mRNA binding ; GO:0003729 | non-traceable author statement "RNA splicing ; GO:0008380 | inferred from electronic annotation with InterPro:IPR013957 hemopoiesis ; GO:0030097 | non-traceable author statement hemocyte differentiation ; GO:0042386 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG18426, l(2)60A-F, bgcn, b(2)gcn, l(2)k13108, l(2)k13214, ytr, YTR, Ytr" IPR013957:U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein CG18426 11-Aug-17 DroID_v2017_08 Drer\snrnp27 - Cele\snrp-27 Xtro\snrnp27 Mmus\Snrnp27 Hsap\SNRNP27 "lethal,recessive,viable,fertile" "hemocyte,supernumerary,lamellocyte,embryonic/larval lymph gland,hemocyte & nucleus | supernumerary,crystal cell,embryonic/larval hemocyte" FBgn0001851 l(1)ts6225 lethal (1) ts6225 http://flybase.org/reports/FBgn0001851 - gene - - - l(1)ts6225 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive" FBgn0020836 l(2)M10 Massachusetts 10 http://flybase.org/reports/FBgn0020836 - gene - - - "l(2)Mass.-10, l(2)M10" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,visible,sterile" "pigment cell,wing" FBgn0004914 Hnf4 Hepatocyte nuclear factor 4 http://flybase.org/reports/FBgn0004914 FBgn0032062 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628 steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR000003, InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000003, InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement" steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 lipid oxidation ; GO:0034440 | inferred from direct assay lipid catabolic process ; GO:0016042 | inferred from direct assay insulin receptor signaling pathway ; GO:0008286 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with HGNC:5024 nucleus ; GO:0005634 | inferred from direct assay "HNF4alpha, dHNF4, HNF-4, HNF4, HNF-4(D), NR2A4, DmHNF4, Hnf-4h, dHNF-4, CG9310, Hnf4, NHF4, Hnf-4" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type, IPR000003:Retinoid X receptor/HNF4" CG9310 11-Aug-17 DroID_v2017_08 "Drer\hnf4a, Drer\hnf4g, Drer\hnf4b" - "Cele\ZK418.11, Cele\nhr-51, Cele\nhr-69, Cele\nhr-37, Cele\nhr-82, Cele\nhr-205, Cele\nhr-5, Cele\nhr-142, Cele\nhr-258, Cele\ZK1037.13, Cele\nhr-106, Cele\nhr-154, Cele\nhr-190, Cele\nhr-262, Cele\nhr-11, Cele\nhr-32, Cele\nhr-6, Cele\nhr-35, Cele\nhr-121, Cele\nhr-173, Cele\nhr-123, Cele\nhr-140, Cele\nhr-207, Cele\nhr-210, Cele\nhr-114, Cele\nhr-201, Cele\nhr-40, Cele\nhr-97, Cele\nhr-189, Cele\nhr-100, Cele\nhr-42, Cele\nhr-78, Cele\nhr-117, Cele\nhr-169, Cele\nhr-203, Cele\nhr-226, Cele\nhr-77, Cele\nhr-216, Cele\nhr-126, Cele\nhr-70, Cele\nhr-119, Cele\nhr-185, Cele\nhr-107, Cele\nhr-53, Cele\nhr-237, Cele\nhr-208, Cele\nhr-214, Cele\nhr-159, Cele\nhr-16, Cele\nhr-92, Cele\nhr-120, Cele\nhr-183, Cele\nhr-95, Cele\nhr-112, Cele\nhr-88, Cele\nhr-89, Cele\nhr-171, Cele\nhr-81, Cele\nhr-242, Cele\Y67D8B.2, Cele\Y47D7A.3, Cele\nhr-283, Cele\nhr-19, Cele\nhr-253, Cele\nhr-84, Cele\nhr-238, Cele\nhr-22, Cele\nhr-198, Cele\nhr-222, Cele\nhr-177, Cele\nhr-152, Cele\nhr-167, Cele\nhr-39, Cele\nhr-193, Cele\nhr-255, Cele\nhr-194, Cele\nhr-94, Cele\nhr-192, Cele\nhr-45, Cele\nhr-1, Cele\nhr-213, Cele\nhr-260, Cele\nhr-172, Cele\nhr-101, Cele\nhr-105, Cele\nhr-136, Cele\nhr-31, Cele\nhr-135, Cele\nhr-261, Cele\nhr-155, Cele\nhr-12, Cele\nhr-174, Cele\nhr-57, Cele\nhr-243, Cele\nhr-221, Cele\nhr-275, Cele\nhr-56, Cele\nhr-232, Cele\nhr-87, Cele\nhr-288, Cele\nhr-34, Cele\nhr-90, Cele\nhr-170, Cele\nhr-44, Cele\nhr-161, Cele\nhr-231, Cele\nhr-98, Cele\nhr-116, Cele\nhr-248, Cele\nhr-36, Cele\nhr-141, Cele\nhr-10, Cele\nhr-138, Cele\ZK418.10, Cele\nhr-175, Cele\nhr-272, Cele\nhr-223, Cele\nhr-181, Cele\nhr-264, Cele\nhr-157, Cele\nhr-59, Cele\nhr-60, Cele\nhr-259, Cele\nhr-147, Cele\nhr-9, Cele\nhr-254, Cele\nhr-113, Cele\nhr-180, Cele\nhr-21, Cele\nhr-150, Cele\nhr-211, Cele\nhr-269, Cele\nhr-127, Cele\nhr-128, Cele\nhr-206, Cele\nhr-49, Cele\nhr-217, Cele\nhr-188, Cele\nhr-145, Cele\nhr-130, Cele\nhr-218, Cele\nhr-129, Cele\nhr-52, Cele\nhr-182, Cele\nhr-20, Cele\nhr-228, Cele\nhr-163, Cele\nhr-179, Cele\nhr-257, Cele\nhr-251, Cele\nhr-199, Cele\nhr-234, Cele\nhr-133, Cele\nhr-18, Cele\nhr-71, Cele\nhr-58, Cele\nhr-55, Cele\nhr-14, Cele\nhr-13, Cele\nhr-285, Cele\nhr-134, Cele\nhr-26, Cele\nhr-165, Cele\nhr-109, Cele\nhr-61, Cele\nhr-3, Cele\nhr-187, Cele\nhr-66, Cele\nhr-273, Cele\nhr-68, Cele\nhr-7, Cele\nhr-270, Cele\nhr-197, Cele\nhr-125, Cele\nhr-267, Cele\nhr-108, Cele\nhr-102, Cele\nhr-103, Cele\nhr-115, Cele\nhr-137, Cele\nhr-65, Cele\nhr-225, Cele\nhr-168, Cele\nhr-268, Cele\nhr-196, Cele\nhr-96, Cele\nhr-54, Cele\nhr-80, Cele\nhr-139, Cele\nhr-162, Cele\nhr-204, Cele\nhr-209, Cele\nhr-156, Cele\nhr-286, Cele\nhr-271, Cele\nhr-47, Cele\nhr-50, Cele\nhr-241, Cele\nhr-38, Cele\nhr-28, Cele\nhr-62, Cele\nhr-153, Cele\nhr-212, Cele\nhr-230, Cele\nhr-110, Cele\nhr-282, Cele\dpr-1, Cele\nhr-186, Cele\nhr-4, Cele\nhr-263, Cele\nhr-131, Cele\nhr-146, Cele\nhr-63, Cele\nhr-46, Cele\nhr-178, Cele\nhr-30, Cele\nhr-244, Cele\nhr-184, Cele\nhr-252, Cele\nhr-76, Cele\nhr-158, Cele\nhr-202, Cele\nhr-64, Cele\nhr-233, Cele\nhr-149, Cele\nhr-256, Cele\nhr-79, Cele\nhr-124, Cele\nhr-235, Cele\nhr-277, Cele\nhr-281, Cele\nhr-132, Cele\nhr-219, Cele\nhr-15, Cele\nhr-86, Cele\nhr-99, Cele\nhr-176, Cele\nhr-118, Cele\nhr-276, Cele\nhr-17, Cele\nhr-122, Cele\nhr-247, Cele\nhr-164, Cele\nhr-274, Cele\nhr-104, Cele\nhr-148, Cele\nhr-166, Cele\nhr-27" "Xtro\hnf4a, Xtro\hnf4b, Xtro\hnf4g" "Mmus\Hnf4a, Mmus\Hnf4g" "Hsap\HNF4A, Hsap\HNF4G" " embryonic stage | stage 1-2 , embryonic stage | stage 11 , embryonic stage | stage 14-15 , embryonic stage " " posterior midgut proper primordium

, Malpighian tubule

, embryonic/larval salivary gland

, anterior midgut proper primordium

, embryonic/larval fat body

" "viable,fertile,stress response defective,eclosion defective,lethal,some die during immature adult stage,recessive" FBgn0000247 ca claret http://flybase.org/reports/FBgn0000247 "FBgn0039699, FBgn0039700, FBgn0039701, FBgn0051037" protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab32 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from physical interaction with Rab32 ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype regulation of Rab protein signal transduction ; GO:0032483 | inferred from direct assay eye pigment precursor transport ; GO:0006856 | traceable author statement eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG31037, bw[G], bw-p, CG18134, CG7799, CG18133, ca" "IPR000408:Regulator of chromosome condensation, RCC1, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR015943:WD40/YVTN repeat-like-containing domain" CG31037 11-Aug-17 DroID_v2017_08 "Drer\rcc2, Drer\als2b, Drer\rpgra, Drer\rccd1, Drer\rcbtb1, Drer\herc2, Drer\ftr97, Drer\rcc1, Drer\rpgrb, Drer\herc1, Drer\als2a, Drer\wbscr16, Drer\sergef, Drer\rcbtb2" "Scer\ATS1, Scer\SRM1, Scer\FMP25" Cele\glo-4 "Xtro\nek9, Xtro\herc2, Xtro\wbscr16, Xtro\herc1, Xtro\als2cl, Xtro\rcbtb2, Xtro\als2, Xtro\rcc1, Xtro\rcbtb1" "Mmus\Nek9, Mmus\Rcc1, Mmus\Wbscr16, Mmus\Herc1, Mmus\Sergef, Mmus\Rpgr, Mmus\Rcc2, Mmus\Rcbtb2, Mmus\Herc2, Mmus\Rccd1, Mmus\Gm15800, Mmus\Als2, Mmus\Rcbtb1" "Hsap\RPGR, Hsap\ALS2, Hsap\RCBTB2, Hsap\NEK9, Hsap\HECTD4, Hsap\HERC1, Hsap\RCC1L, Hsap\HERC2, Hsap\RCC2, Hsap\RCC1, Hsap\RCCD1, Hsap\RCBTB1, Hsap\SERGEF" "visible,recessive,eye color defective,wild-type,female sterile,male sterile,viable" "ocellus,pigment cell,eye,Malpighian tubule,wing,abdomen,primary pigment cell pigment granule,secondary pigment cell pigment granule,tertiary pigment cell pigment granule,male genitalia,female genitalia" FBgn0045866 bai baiser http://flybase.org/reports/FBgn0045866 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence model "transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR009038 regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype reproduction ; GO:0000003 | inferred from mutant phenotype maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred from sequence model" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 endomembrane system ; GO:0012505 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "150547_at, CG11785, BcDNA:RE52411, bai, p23, BAI, p24, Bai" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG11785 11-Aug-17 DroID_v2017_08 Drer\tmed10 Scer\ERV25 Cele\F47G9.1 Xtro\tmed10 "Mmus\Tmed10, Mmus\Ticam2" "Hsap\TICAM2, Hsap\TMED10" "partially lethal - majority die,lethal,maternal effect,partially lethal - majority live,recessive,female sterile,male semi-sterile,germline clone,non-rescuable maternal effect,viable,female semi-sterile" "embryonic/first instar larval cuticle,dorsal,germline clone,wing vein,ectopic" FBgn0020521 pio piopio http://flybase.org/reports/FBgn0020521 FBgn0035030 protein_coding_gene molecular_function ; GO:0003674 | no biological data available open tracheal system development ; GO:0007424 | inferred from mutant phenotype chitin-based cuticle attachment to epithelium ; GO:0040005 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype apical part of cell ; GO:0045177 | inferred from direct assay "pio, CG3541, CG30167, Pio, piopio" IPR001507:Zona pellucida domain CG3541 11-Aug-17 DroID_v2017_08 "Drer\zgc:153932, Drer\si:ch211-229d2.5, Drer\zmp:0000001031, Drer\si:ch211-103f14.3" - "Cele\cutl-15, Cele\cutl-8, Cele\cutl-26, Cele\F46G11.6, Cele\cutl-11, Cele\cutl-4, Cele\cutl-22, Cele\ram-5, Cele\cutl-28, Cele\cut-5, Cele\cutl-14, Cele\cutl-16, Cele\cutl-29, Cele\cut-6, Cele\cutl-24, Cele\cutl-19, Cele\cutl-23, Cele\cutl-10, Cele\cut-3, Cele\cut-1, Cele\cutl-9, Cele\cutl-12, Cele\cutl-13, Cele\cutl-17, Cele\dpy-1, Cele\cutl-7, Cele\cutl-1, Cele\cutl-6, Cele\T01D1.8, Cele\cutl-5, Cele\cutl-2, Cele\cutl-20, Cele\cutl-3, Cele\cutl-25, Cele\cut-4" "Xtro\thdl18, Xtro\MGC89178, Xtro\thdl17" - - "viable,fertile,visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "presumptive embryonic/larval tracheal system,wing,somatic clone,embryonic/larval somatic muscle,segment,posterior,cerebral branch,ventral cephalic branch,pharyngeal branch,dorsal branch,visceral branch,lateral trunk anterior branch,lateral trunk posterior branch,adult external thorax,wing blade,cytoplasmic microtubule & wing | somatic clone,embryonic/first instar larval cuticle,embryonic/larval tracheal system,endocuticle" FBgn0002359 l(3)87Eg lethal (3) 87Eg http://flybase.org/reports/FBgn0002359 FBgn0011806 gene - - - "1437/04, 0616/17, m17, l(3)s2149, l(3)m17, l(3)87Eg" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage" FBgn0000559 eEF2 eukaryotic translation elongation factor 2 http://flybase.org/reports/FBgn0000559 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR005225, InterPro:IPR005517 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity" translational elongation ; GO:0006414 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity "Ef2b, EF2, CG2238, eEF2, clone 1.44, EF-2b, EF-2, anon-EST:Liang-1.44, Ef2, ef2b, eF2, EF2b, chr2L:21668915..21669164, EF2B, Ef2B" "IPR000640:Translation elongation factor EFG, V domain, IPR000795:Transcription factor, GTP-binding domain, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR005225:Small GTP-binding protein domain, IPR005517:Translation elongation factor EFG/EF2, domain IV, IPR009000:Translation protein, beta-barrel domain, IPR009022:Elongation factor G, III-V domain, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031157:Tr-type G domain, conserved site" CG2238 11-Aug-17 DroID_v2017_08 "Drer\eftud2, Drer\eef2a.1, Drer\eef2b, Drer\eef2a.2, Drer\eef2l2" "Scer\EFT1, Scer\EFT2, Scer\SNU114" Cele\eef-2 "Xtro\eftud2, Xtro\eef2.1, Xtro\eef2.2" "Mmus\Eef2, Mmus\Eftud2" "Hsap\EEF2, Hsap\EFTUD2" lethal DRSC03737 IE -1.978513292 -1.655755324 -0.951468627 -2.780725022 -1.305737747 0.318067274 FBgn0032816 Nf-YB Nuclear factor Y-box B http://flybase.org/reports/FBgn0032816 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay "positive regulation of R7 cell differentiation ; GO:0045678 | inferred from mutant phenotype positive regulation of MAPK cascade ; GO:0043410 | inferred from genetic interaction with Raf inferred from genetic interaction with sev positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype" CCAAT-binding factor complex ; GO:0016602 | inferred from direct assay "Nf-YB, BcDNA:RH50436, CG10447, NF-YB, dNF-YB" "IPR003958:Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072:Histone-fold" CG10447 11-Aug-17 DroID_v2017_08 "Drer\pole3, Drer\nfyba, Drer\nfybb" Scer\HAP3 Cele\nfyb-1 "Xtro\nfyb, Xtro\glrx2" "Mmus\Pole3, Mmus\Nfyb" "Hsap\POLE3, Hsap\NFYB" "viable,increased cell death,mitotic cell cycle defective" "eye,ommatidium,interommatidial bristle,eye disc posterior to the morphogenetic furrow,photoreceptor cell R7 | third instar larval stage" FBgn0052350 Vps11 Vacuolar protein sorting 11 http://flybase.org/reports/FBgn0052350 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000004844 protein binding, bridging ; GO:0030674 | inferred from biological aspect of ancestor with PANTHER:PTN000595174" lysosome organization ; GO:0007040 | inferred from biological aspect of ancestor with PANTHER:PTN000595174 vesicle docking involved in exocytosis ; GO:0006904 | inferred from biological aspect of ancestor with PANTHER:PTN000595174 regulation of SNARE complex assembly ; GO:0035542 | inferred from sequence or structural similarity with SGD:S000004844 autophagosome maturation ; GO:0097352 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype regulation of SNARE complex assembly ; GO:0035542 | inferred from biological aspect of ancestor with PANTHER:PTN000595174 lysosomal transport ; GO:0007041 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000004844 histone ubiquitination ; GO:0016574 | inferred from sequence or structural similarity with SGD:S000004844 endosome organization ; GO:0007032 | inferred from biological aspect of ancestor with PANTHER:PTN000595174 HOPS complex ; GO:0030897 | inferred from mutant phenotype CORVET complex ; GO:0033263 | inferred from sequence or structural similarity with SGD:S000004844 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000595174 HOPS complex ; GO:0030897 | inferred from sequence or structural similarity with SGD:S000004844 "BcDNA:LD20292, Vps11, CG32350" "IPR001841:Zinc finger, RING-type, IPR016528:Vacuolar protein sorting-associated protein 11, IPR011990:Tetratricopeptide-like helical domain" CG32350 11-Aug-17 DroID_v2017_08 "Drer\vps11, Drer\vps18" Scer\PEP5 Cele\vps-11 Xtro\vps11 Mmus\Vps11 Hsap\VPS11 "viable,body color defective" "embryonic/larval fat body,nutrition conditional,autolysosome | wandering third instar larval stage | nutrition conditional,autophagic vacuole | supernumerary | wandering third instar larval stage | nutrition conditional,mesothoracic tergum,somatic clone,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0000802 fs(1)de13 female sterile (1) defective eggs 13 http://flybase.org/reports/FBgn0000802 - gene - - - "de13, fs(1)de13" - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile "dorsal appendage,chorion,endochorion" FBgn0038068 CG11600 - http://flybase.org/reports/FBgn0038068 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - CG11600 "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG11600 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\TGL1, Scer\YEH2, Scer\YEH1" "Cele\lipl-1, Cele\lipl-3, Cele\lipl-4, Cele\lipl-2, Cele\lipl-6, Cele\lipl-5, Cele\lipl-8, Cele\lipl-7" Xtro\lipa "Mmus\Lipm, Mmus\Lipo4, Mmus\Lipn, Mmus\Lipo3, Mmus\Lipf, Mmus\Lipo1, Mmus\Lipk, Mmus\Lipa, Mmus\Lipo2" "Hsap\LIPF, Hsap\LIPA, Hsap\LIPN, Hsap\LIPJ, Hsap\LIPM, Hsap\LIPK" viable DRSC14332 K 0.298879353 -0.287267075 -0.23162695 0.356861871 0.775563978 -1.601275645 FBgn0033687 CG8407 - http://flybase.org/reports/FBgn0033687 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR001372 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from electronic annotation with InterPro:IPR001372 dynein complex ; GO:0030286 | inferred from sequence or structural similarity CG8407 "IPR001372:Dynein light chain, type 1/2" CG8407 11-Aug-17 DroID_v2017_08 "Drer\dynll2b, Drer\dnal4a, Drer\dnal4b, Drer\dynll2a" Scer\DYN2 "Cele\dlc-3, Cele\dlc-4" "Xtro\dynll2, Xtro\dnal4, Xtro\dynll1" "Mmus\Dnal4, Mmus\BC048507, Mmus\Dynll2, Mmus\Dynll1" "Hsap\DYNLL1, Hsap\DYNLL2, Hsap\DNAL4" viable FBgn0000332 Cma Comma http://flybase.org/reports/FBgn0000332 - gene - - - Cma - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,flightless,lethal,recessive" "dorsal mesothorax,dorsocentral bristle,adult cuticle,myofibril & indirect flight muscle" FBgn0021765 scu scully http://flybase.org/reports/FBgn0021765 FBgn0001550 protein_coding_gene acetoacetyl-CoA reductase activity ; GO:0018454 | inferred from direct assay steroid dehydrogenase activity ; GO:0016229 | inferred from direct assay 7-beta-hydroxysteroid dehydrogenase (NADP+) activity ; GO:0047022 | inferred from direct assay testosterone dehydrogenase (NAD+) activity ; GO:0047035 | inferred from direct assay estradiol 17-beta-dehydrogenase activity ; GO:0004303 | inferred from direct assay ecdysone metabolic process ; GO:0008205 | inferred from direct assay estrogen metabolic process ; GO:0008210 | inferred from direct assay ATP metabolic process ; GO:0046034 | inferred from mutant phenotype steroid metabolic process ; GO:0008202 | inferred from direct assay acyl-CoA metabolic process ; GO:0006637 | inferred from direct assay fatty acid metabolic process ; GO:0006631 | inferred from direct assay mitochondrial tRNA processing ; GO:0090646 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype androgen metabolic process ; GO:0008209 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O08756 lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay "Scu, 17beta-HSD10, CG7113, HL-X, HLII, l(1)17Ad, l(1)16Fd, scu, MRPP2" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG7113 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-238o13.4, Drer\hsd17b10" "Scer\IRC24, Scer\YIR035C, Scer\YDL114W, Scer\TDA5, Scer\SPS19, Scer\AYR1" "Cele\C06E4.3, Cele\ard-1, Cele\dhs-11" Xtro\hsd17b10 Mmus\Hsd17b10 Hsap\HSD17B10 " adult stage | female , larval stage | third instar , larval stage , embryonic stage , embryonic stage | late , adult stage | male " " imaginal disc

, gonad

, Malpighian tubule

, gonad | primordium

, embryonic/larval salivary gland

, epithelial cell &&of midgut

, larval central nervous system

" "lethal,some die during pupal stage,viable,fertile,recessive,wild-type,neurophysiology defective,germline clone,polyphasic,lethal - all die before end of pupal stage" "oogonial cell,germline clone,spermatocyte,testis,spermatocyte & mitochondrion,ommatidium,somatic clone,eye photoreceptor cell,rhabdomere,eye photoreceptor cell & mitochondrion | somatic clone,spermatocyte & nucleolus" FBgn0036099 CG11811 - http://flybase.org/reports/FBgn0036099 protein_coding_gene guanylate kinase activity ; GO:0004385 | inferred from biological aspect of ancestor with PANTHER:PTN000563396 purine nucleotide metabolic process ; GO:0006163 | inferred from sequence or structural similarity with HGNC:4693 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002862 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002862 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000563396 CG11811 "IPR008144:Guanylate kinase-like domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017665:Guanylate kinase, IPR020590:Guanylate kinase, conserved site" CG11811 11-Aug-17 DroID_v2017_08 "Drer\lrrc23, Drer\guk1b, Drer\lrguk, Drer\LOC556872, Drer\LOC564220, Drer\magi3a, Drer\guk1a" Scer\GUK1 Cele\guk-1 "Xtro\guk1, Xtro\magi3, Xtro\lrrc23" "Mmus\Guk1, Mmus\Lrguk, Mmus\Magi3, Mmus\Lrrc23" "Hsap\LRGUK, Hsap\GUK1, Hsap\MAGI3, Hsap\LRRC23" "viable,fertile,visible" trichogen cell FBgn0000308 chic chickadee http://flybase.org/reports/FBgn0000308 FBgn0013731 protein_coding_gene actin monomer binding ; GO:0003785 | inferred from biological aspect of ancestor with PANTHER:PTN000176159 actin binding ; GO:0003779 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8T4F7 protein binding ; GO:0005515 | inferred from physical interaction with dia larval central nervous system remodeling ; GO:0035193 | inferred from genetic interaction with cib dorsal closure ; GO:0007391 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype actin filament polymerization ; GO:0030041 | traceable author statement spermatogenesis ; GO:0007283 | inferred from mutant phenotype positive regulation of axon extension involved in axon guidance ; GO:0048842 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | traceable author statement ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype actin filament organization ; GO:0007015 | traceable author statement neuron remodeling ; GO:0016322 | inferred from mutant phenotype inferred from genetic interaction withFB:FBgn0262735 pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement histoblast morphogenesis ; GO:0007488 | inferred from mutant phenotype sequestering of actin monomers ; GO:0042989 | inferred from biological aspect of ancestor with PANTHER:PTN000176159 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype positive regulation of axon regeneration ; GO:0048680 | inferred from mutant phenotype inferred from genetic interaction withFB:FBgn0262735 brain development ; GO:0007420 | inferred from mutant phenotype somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from genetic interaction with cib actin filament organization ; GO:0007015 | inferred from mutant phenotype cell cortex ; GO:0005938 | inferred from biological aspect of ancestor with PANTHER:PTN000176159 perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay actin cytoskeleton ; GO:0015629 | inferred from biological aspect of ancestor with PANTHER:PTN000176159 neuron projection ; GO:0043005 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "chic, profilin, sand, Chi, Chic, CG9553, chi, l(2)27/7, D88, GH4, chickadee" "IPR005455:Profilin, IPR027310:Profilin conserved site" CG9553 11-Aug-17 DroID_v2017_08 "Drer\pfn2l, Drer\pfn1, Drer\pfn2" Scer\PFY1 "Cele\pfn-2, Cele\pfn-3, Cele\pfn-1" "Xtro\pfn2, Xtro\pfn1" "Mmus\Pfn4, Mmus\Pfn2, Mmus\Pfn1" "Hsap\PFN1, Hsap\PFN2, Hsap\PFN4" " adult stage | male , oogenesis stage && adult stage | female " ovary

" embryonic stage | stage 16 , embryonic stage -- adult stage , adult stage && oogenesis stage , embryonic stage " " ventral nerve cord

, nurse cell

, follicle cell

, border follicle cell

" "female sterile,recessive,male sterile,visible,neuroanatomy defective,somatic clone,lethal,female semi-sterile,cell shape defective,dominant,maternal effect,wound healing defective,male fertile,female fertile,poor,viable,fertile,male semi-sterile,cytokinesis defective,male,partially lethal - majority die,axis specification defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "macrochaeta,onion stage spermatid,aster & meiotic cell cycle | male,nurse cell,border follicle cell,oocyte,egg chamber,nurse cell ring canal,egg,karyosome,embryonic/larval salivary gland,stage S8 oocyte,maternal effect,chorion | maternal effect,dorsal appendage,follicle cell,somatic clone,stress fiber | somatic clone,testis,contractile ring & meiotic cell cycle | male,spindle & meiotic cell cycle | male,secondary spermatocyte,spermatocyte,cleavage furrow & spermatocyte,longitudinal connective,filopodium,adult mushroom body,follicle cell & actin filament | somatic clone,embryonic/larval neuron,intersegmental nerve,filopodiumGpdhA),motor neuron,spermatocyte ring canal,spermatid,meiotic cell cycle,Nebenkern,crossvein,ectopic,embryonic/first instar larval cuticle,dorsal,embryonic dorsal epidermis,embryonic leading edge cell,photoreceptor cell & eye disc | somatic clone,actin filament & eye disc | somatic clone,morphogenetic furrow,wing,embryonic somatic muscle,anterior embryonic/larval midgut,embryonic proventriculus,cyst cell,sternopleural bristle,germarium,microchaeta,LNv neuron,ventral adult lateral neuron & commissureP2.4.Pdf,histoblast nest,adult abdomen,embryonic epidermis,trichogen cell & actin filament & pupa" FBgn0017418 ari-1 ariadne 1 http://flybase.org/reports/FBgn0017418 FBgn0014203 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model protein dimerization activity ; GO:0046983 | inferred from physical interaction with ari-1 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with Ubc10 positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 protein ubiquitination ; GO:0016567 | inferred from direct assay endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 positive regulation of neurogenesis ; GO:0050769 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 "Ari-1, CG5659, ari, HL-V, l(1)16Fj, ari-1, AAS65398.1, ari-1a, ARI1_DROME" "IPR001841:Zinc finger, RING-type, IPR002867:IBR domain, IPR018957:Zinc finger, C3HC4 RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR031127:E3 ubiquitin ligase RBR family" CG5659 11-Aug-17 DroID_v2017_08 "Drer\arih1l, Drer\si:ch211-278j3.3, Drer\ankib1b, Drer\arih2, Drer\shrprbck1r, Drer\rnf19b, Drer\ankib1a, Drer\rnf144aa, Drer\arih1, Drer\rnf19a, Drer\rbck1, Drer\rnf144ab, Drer\rnf144b, Drer\rnf217" Scer\HEL1 "Cele\T12E12.1, Cele\ari-1, Cele\C27A12.6, Cele\C27A12.7, Cele\tag-349" "Xtro\rnf144a, Xtro\arih2, Xtro\cul9, Xtro\rnf19a, Xtro\arih1, Xtro\rnf217, Xtro\rnf144b" "Mmus\Arih1, Mmus\Rnf144a, Mmus\Rbck1, Mmus\Cul9, Mmus\Cul7, Mmus\Rnf19a, Mmus\Rnf217, Mmus\Rnf19b, Mmus\Rnf144b, Mmus\Arih2, Mmus\Ankib1, Mmus\Sharpin" "Hsap\RNF19B, Hsap\RBCK1, Hsap\ARIH1, Hsap\RNF19A, Hsap\RNF144B, Hsap\CUL9, Hsap\ANKIB1, Hsap\RNF217, Hsap\RNF144A, Hsap\CUL7, Hsap\ARIH2" " embryonic stage -- adult stage , adult stage && oogenesis stage , adult stage | female , adult stage , larval stage " " nurse cell

, gonad

, follicle cell

, adult central nervous system

,

ubiquitous " " embryonic stage -- adult stage , egg stage | unfertilized egg " unfertilized egg

"visible,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,viable,partially lethal - majority die,fertile,lethal - all die before end of pupal stage,some die during pupal stage,poor,lethal,female sterile,germline clone,non-rescuable maternal effect,neuroanatomy defective,somatic clone,neurophysiology defective,flightless,jumping defective,courtship behavior defective,male,locomotor behavior defective" "wing,coxal tergal remotor muscle,mesothoracic extracoxal depressor muscle 66,ovariole,germline cyst,rhabdomere R1,somatic clone,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,photoreceptor cell R1 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R2 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R3 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R4 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R5 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R6 & rough endoplasmic reticulum | somatic clone,photoreceptor cell R7 & rough endoplasmic reticulum | somatic clone,optic lobe,adult brain,thoracico-abdominal ganglion,cervical connective,macrochaeta" DRSC21603 IK 1.063687657 1.596058135 0.029016339 0.002714213 1.508595669 1.122542465 FBgn0028241 l(3)S001620a lethal (3) S001620a http://flybase.org/reports/FBgn0028241 gene - - - "0016/20, l(3)S001620, l(3)S001620a" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0001202 hook hook http://flybase.org/reports/FBgn0001202 - protein_coding_gene dynein light intermediate chain binding ; GO:0051959 | inferred from biological aspect of ancestor with PANTHER:PTN000436622 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab5 microtubule binding ; GO:0008017 | inferred from direct assay cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000436622 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype endosomal transport ; GO:0016197 | traceable author statement cytoskeleton-dependent intracellular transport ; GO:0030705 | inferred from direct assay R7 cell development ; GO:0045467 | traceable author statement endocytosis ; GO:0006897 | traceable author statement endocytosis ; GO:0006897 | inferred from expression pattern phagocytosis ; GO:0006909 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from expression pattern inferred from mutant phenotype endosome ; GO:0005768 | inferred from direct assay centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000436622 cytoplasm ; GO:0005737 | non-traceable author statement synapse ; GO:0045202 | inferred from mutant phenotype "dHk, CG10653, hook, hk, Hook" IPR008636:Hook-related protein family CG10653 11-Aug-17 DroID_v2017_08 "Drer\hook1, Drer\hook2" - "Cele\B0286.1, Cele\grdn-1, Cele\zyg-12" "Xtro\hook1, Xtro\hook2, Xtro\hook3" "Mmus\Hook1, Mmus\Hook2, Mmus\Hook3" "Hsap\HOOK3, Hsap\HOOK1, Hsap\HOOK2" embryonic stage -- adult stage "viable,fertile,visible,recessive,wild-type,short lived,male,neurophysiology defective,neuroanatomy defective" "macrochaeta,macrochaeta & head,macrochaeta & thorax,ommatidium,multivesicular body,lysosome,endosome,synapse,bouton,supernumerary,glial cell,eye disc" DRSC03545 K -0.376992752 -0.102187248 0.066822142 0.431928205 0.251338682 -1.565422544 FBgn0000068 alo alopecia http://flybase.org/reports/FBgn0000068 - gene - - - alo - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,good,male,female,reduced,male fertile,female fertile,visible,recessive,fertile" microchaeta & adult abdomen FBgn0036927 Gabat gamma-aminobutyric acid transaminase http://flybase.org/reports/FBgn0036927 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR005814 4-aminobutyrate transaminase activity ; GO:0003867 | inferred from sequence or structural similarity with UniProtKB:P80404 gamma-aminobutyric acid metabolic process ; GO:0009448 | inferred from electronic annotation with InterPro:IPR004631 regulation of glutamate metabolic process ; GO:2000211 | inferred from mutant phenotype cellular amino acid metabolic process ; GO:0006520 | inferred from sequence or structural similarity with UniProtKB:P80404 regulation of carbohydrate metabolic process ; GO:0006109 | inferred from mutant phenotype regulation of circadian sleep/wake cycle ; GO:0042749 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P80404 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P80404 "149085_at, CG7433, gabat, GABAT, Gabat" "IPR004631:4-aminobutyrate aminotransferase, eukaryotic, IPR005814:Aminotransferase class-III, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG7433 11-Aug-17 DroID_v2017_08 "Drer\abat, Drer\trappc8" Scer\UGA1 "Cele\gta-1, Cele\trpp-8" "Xtro\trappc8, Xtro\abat" "Mmus\Abat, Mmus\Trappc8" Hsap\ABAT "viable,fertile" FBgn0026432 Grip163 Grip163 http://flybase.org/reports/FBgn0026432 FBgn0036238 protein_coding_gene microtubule minus-end binding ; GO:0051011 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin binding ; GO:0043015 | inferred from direct assay structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 meiotic nuclear division ; GO:0007126 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 interphase microtubule nucleation by interphase microtubule organizing center ; GO:0051415 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 equatorial microtubule organizing center ; GO:0000923 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 centrosome ; GO:0005813 | inferred from direct assay gamma-tubulin ring complex ; GO:0008274 | inferred from sequence or structural similarity with Grip91 inferred from sequence or structural similarity with Grip84 inferred from sequence or structural similarity with Grip75 inferred from physical interaction with γTub23C "Dgrip163, Dgrips163, grip163, CG5688, Grip163, GCP6, DGrip163" IPR007259:Gamma-tubulin complex component protein CG5688 11-Aug-17 DroID_v2017_08 "Drer\tubgcp3, Drer\tubgcp6, Drer\tubgcp5" "Scer\SPC98, Scer\SPC97" Cele\droe-4 "Xtro\tubgcp5, Xtro\tubgcp3, Xtro\tubgcp2, Xtro\tubgcp6" "Mmus\Tubgcp6, Mmus\Tubgcp3, Mmus\Tubgcp2, Mmus\Tubgcp5" "Hsap\TUBGCP5, Hsap\TUBGCP6, Hsap\TUBGCP2, Hsap\TUBGCP3" "lethal,viable,mitotic cell cycle defective,partially lethal - majority live,female sterile" "S2 cell-line,spindle,adult external abdomen" FBgn0052036 CG32036 - http://flybase.org/reports/FBgn0052036 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG3426, CG32036" IPR002557:Chitin binding domain CG32036 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - "viable,fertile" DRSC10362 E 0.172613795 -0.355815965 2.113244976 0.378479261 0.485455217 0.4156102 FBgn0017561 Ork1 Open rectifier K[+] channel 1 http://flybase.org/reports/FBgn0017561 "FBgn0046859, FBgn0046860, FBgn0046861" protein_coding_gene potassium ion leak channel activity ; GO:0022841 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Ork1 locomotor rhythm ; GO:0045475 | inferred from mutant phenotype regulation of heart rate ; GO:0002027 | inferred from mutant phenotype potassium ion transmembrane transport ; GO:0071805 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:6272 inferred from sequence or structural similarity with SGD:S000003629 potassium channel complex ; GO:0034705 | inferred from direct assay "dORK, KCNK0, ORK1, d-ORK1, CG1615, anon-WO0161006.23, anon-WO0161006.22, anon-WO0161006.1, Ork1, ORK, K[[2P]], DorK, ork1, dORK1, ORK-1, dOrk, dOrk1, dORKC1" "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG1615 11-Aug-17 DroID_v2017_08 "Drer\kcnk1a, Drer\kcnk6, Drer\kcnk2b, Drer\kcnk15, Drer\kcnk3b, Drer\kcnk2a, Drer\kcnk17, Drer\kcnk7, Drer\kcnk1b, Drer\kcnk3a, Drer\LOC101882857, Drer\kcnk5b, Drer\kcnk10b, Drer\kcnk4a, Drer\kcnk10a, Drer\kcnk18, Drer\kcnk5a, Drer\kcnk9" Scer\TOK1 "Cele\twk-5, Cele\sup-9, Cele\twk-20, Cele\twk-46" "Xtro\kcnk2, Xtro\kcnk18, Xtro\kcnk10, Xtro\kcnk4, Xtro\kcnk7, Xtro\kcnk5, Xtro\LOC100486031, Xtro\kcnk16, Xtro\kcnk1, Xtro\kcnk6" "Mmus\Kcnk3, Mmus\Kcnk15, Mmus\Kcnk18, Mmus\Kcnk2, Mmus\Kcnk9, Mmus\Kcnk5, Mmus\Kcnk7, Mmus\Kcnk10, Mmus\Kcnk1, Mmus\Kcnk4, Mmus\Kcnk6, Mmus\Kcnk16" "Hsap\KCNK1, Hsap\KCNK4, Hsap\KCNK2, Hsap\KCNK18, Hsap\KCNK10, Hsap\KCNK17, Hsap\KCNK16, Hsap\KCNK5, Hsap\KCNK15, Hsap\KCNK9, Hsap\KCNK6, Hsap\KCNK3, Hsap\KCNK7" " adult stage , embryonic stage && larval stage && adult stage , adult stage && oogenesis stage " " adult muscle system

, adult brain

, ovary

" "neuroanatomy defective,viable,fertile,lethal,locomotor rhythm defective,phototaxis defective,sleep defective,neurophysiology defective,behavior defective,developmental rate defective,small body,visual behavior defective" "embryonic/larval olfactory receptor neuron | first instar larval stage,embryonic/larval heart,projection neuron,Kenyon cell,presynaptic active zoneMz19" FBgn0067647 sd-9 sd-9 http://flybase.org/reports/FBgn0067647 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-9 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,somatic clone,neuroanatomy defective,phototaxis defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "photoreceptor cell & axon | somatic clone,lamina,somatic clone,medulla,lobula plate,lobula" FBgn0015795 Rab7 Rab7 http://flybase.org/reports/FBgn0015795 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity protein complex binding ; GO:0032403 | inferred from physical interaction with Vps35 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" dsRNA transport ; GO:0033227 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 exosomal secretion ; GO:1990182 | inferred from mutant phenotype endosome to lysosome transport via multivesicular body sorting pathway ; GO:0032510 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern endocytosis ; GO:0006897 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with l(2)gd1 endosomal transport ; GO:0016197 | traceable author statement inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | traceable author statement inferred from genetic interaction with dpp endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern negative regulation of growth of symbiont in host ; GO:0044130 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 lipid particle ; GO:0005811 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay late endosome ; GO:0005770 | "Rab7, Dm Rab7, AAF56218, Rab-7, DmRab7, CG5915, DRab7, rab7, RAB7, Drab7, DRAB7, Rab-r7, O76742, drab7, dRab7, Rab7A" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5915 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-13a21.4, Drer\zgc:91909, Drer\rab9a, Drer\rab7, Drer\rab9b, Drer\zgc:100918" Scer\YPT7 Cele\rab-7 "Xtro\rab9b, Xtro\rab9a, Xtro\rab7a, Xtro\MGC75872, Xtro\rab7b" "Mmus\Rab9, Mmus\Rab9b, Mmus\Rab7b, Mmus\Rab7" "Hsap\RAB7B, Hsap\RAB9A, Hsap\RAB9B, Hsap\RAB7A" "neuroanatomy defective,lethal - all die before end of pupal stage,recessive,neurophysiology defective,progressive,somatic clone,dominant,viable,fertile,lethal,visible,immune response defective" "dorsal multidendritic neuron ddaC,photoreceptor,progressive,somatic clone,rhabdomere | progressive | somatic clone,synapse | progressive | somatic clone,rhabdomere,synapse,wing,posterior compartment,late endosomeunspecified,glial cell,eye disc,endosomehh-Gal4,endosomeptc-559.1,multivesicular bodyptc-559.1,lysosomeCY2,vesicleeg-Mz360,oocyte,mitochondrial derivativemat.‘±Tub67C.THsimVP16,phagocytic vesicleHml.‘î,hemocyte | adult stage" FBgn0023010 l(3)S074205 lethal (3) S074205 http://flybase.org/reports/FBgn0023010 - gene - - - "742/5, 0742/05, l(3)S074205" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0083070 omt omelette http://flybase.org/reports/FBgn0083070 gene - meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype - omt - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,male,cytokinesis defective,recessive" "spermatid & nucleus | supernumerarye-F1),Nebenkern,spindle & meiotic telophase I | malee-F1),contractile ring & meiotic telophase I | malee-F1),spindle & meiotic telophase II | malee-F1),contractile ring & meiotic telophase II | malee-F1),spermatid & nucleus | supernumerary,spindle & meiotic telophase I | male,contractile ring & meiotic telophase I | male,spindle & meiotic telophase II | male,contractile ring & meiotic telophase II | male" FBgn0033096 Zip42C.1 Zinc/iron regulated transporter-related protein 42C.1 http://flybase.org/reports/FBgn0033096 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0010312 zinc ion transmembrane transporter activity ; GO:0005385 | inferred from direct assay adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype zinc ion homeostasis ; GO:0055069 | inferred from mutant phenotype zinc II ion transmembrane import ; GO:0071578 | inferred from genetic interaction with Zip42C.2 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "dZIP1, CG9428, dZip42C.1, Zip1, dZip1, Zip42C.1, cg9428, ZIP1, dZIP42C.1" IPR003689:Zinc/iron permease CG9428 11-Aug-17 DroID_v2017_08 "Drer\slc39a3, Drer\slc39a1" "Scer\WSS1, Scer\ZRT1, Scer\ZRT2" "Cele\F31C3.4, Cele\F55F8.9, Cele\C18A3.2, Cele\F30B5.7, Cele\Y54G9A.4, Cele\C06G8.3" "Xtro\slc39a2, Xtro\slc39a1, Xtro\slc39a1, Xtro\slc39a3" "Mmus\Slc39a3, Mmus\Slc39a1, Mmus\Slc39a2" "Hsap\SLC39A10, Hsap\SLC39A1, Hsap\SLC39A3, Hsap\SLC39A2" "visible,conditional,chemical sensitive,lethal - all die during larval stage,chemical resistant,locomotor behavior defective,short lived,viable,melanotic mass phenotype" "eye,conditional,melanotic mass" FBgn0031390 tho2 tho2 http://flybase.org/reports/FBgn0031390 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000492184 mRNA export from nucleus in response to heat stress ; GO:0031990 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay THO complex ; GO:0000347 | inferred from direct assay THO complex part of transcription export complex ; GO:0000445 | inferred from biological aspect of ancestor with PANTHER:PTN000492184 transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:19073 "Tho2, CG31671, CG4263, tho2, Thoc2, THO2, macadamia" "IPR021418:THO complex, subunitTHOC2, C-terminal, IPR021726:THO complex, subunitTHOC2, N-terminal, IPR032302:THO complex subunit 2, N-terminal domain" CG31671 11-Aug-17 DroID_v2017_08 "Drer\zc3h13, Drer\thoc2" Scer\THO2 Cele\thoc-2 "Xtro\thoc2, Xtro\zc3h13" "Mmus\Zc3h13, Mmus\BC005561, Mmus\Thoc2" "Hsap\THOC2, Hsap\ZC3H13" "viable,fertile,lethal,cell polarity defective,germline clone,visible,somatic clone,female fertile" "egg chamber,germline clone,oocyte,centrosome | germline clone,macrochaeta,somatic clone,mesothoracic tergum" DRSC00646 I 2.327689702 1.046641532 -0.14126571 1.034547605 -0.536008577 1.457503326 FBgn0060831 l(3)S050116b lethal (3) S050116b http://flybase.org/reports/FBgn0060831 gene - - - "l(3)S050116, 0501/16, l(3)S050116b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0261870 pky pokey http://flybase.org/reports/FBgn0261870 gene - - - pky - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015993 l(2)k06712 lethal (2) k06712 http://flybase.org/reports/FBgn0015993 - gene - - - l(2)k06712 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system" FBgn0004098 l(2)60Df lethal (2) 60Df http://flybase.org/reports/FBgn0004098 - gene - - - l(2)60Df - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0041097 robo3 roundabout 3 http://flybase.org/reports/FBgn0041097 protein_coding_gene - axon guidance ; GO:0007411 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype neuron recognition ; GO:0008038 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype central complex development ; GO:0048036 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype axon guidance ; GO:0007411 | traceable author statement axon ; GO:0030424 | inferred from direct assay "robo3, CG5423, Robo-3, Robo3, CT17158, dRobo-3, CG14345, Robo 3, ROBO3" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR013106:Immunoglobulin V-set domain" CG5423 11-Aug-17 DroID_v2017_08 "Drer\igsf9b, Drer\robo3, Drer\robo1, Drer\robo4, Drer\igsf9a, Drer\robo2" - Cele\sax-3 "Xtro\igsf9b, Xtro\robo3, Xtro\robo4, Xtro\robo1" "Mmus\Robo1, Mmus\Robo2, Mmus\Robo3, Mmus\Robo4, Mmus\Igdcc3, Mmus\Igsf9b, Mmus\Prtg" "Hsap\ROBO3, Hsap\ROBO4, Hsap\IGDCC3, Hsap\ROBO2, Hsap\IGSF9B, Hsap\ROBO1" embryonic stage | stage 13-15 embryonic central nervous system

"neuroanatomy defective,viable,somatic clone,partially lethal - majority die,recessive,male,neurophysiology defective,partially,fertile" "photoreceptor cell R8,medulla,somatic clone,eye photoreceptor cell,olfactory neuron & antennal lobeSG18.1,olfactory neuron & antennal lobelz-gal4,antennal lobe glomerulus,ectopic,embryonic/larval neuron,ventral nerve cord commissure,VL fascicle,dendritic arborizing neuron,lateral multidendritic neuron ldaA,longitudinal connective,intermediate longitudinal fascicle,medial longitudinal fascicle,interface glial cell,chordotonal organ & embryo & nerve terminal,antennal lobe glomerulus DM2,olfactory neuron & antennal lobe | somatic clone,ellipsoid body,mushroom body gamma-lobe,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,gonad,germline cell,prothoracic leg taste bristle chemosensory neuron,male,eye,giant fiber neuron,abdominal basiconical sensillum dbd & embryo & nerve terminal12.1" DRSC00684 I 1.744209997 -0.130005281 0.003825148 -0.593864269 -0.362651588 -0.359816461 FBgn0039346 CG5079 - http://flybase.org/reports/FBgn0039346 protein_coding_gene - - - CG5079 IPR015943:WD40/YVTN repeat-like-containing domain CG5079 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027289 l(1)G0164 lethal (1) G0164 http://flybase.org/reports/FBgn0027289 - gene - - - l(1)G0164 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0037613 Cks85A Cyclin-dependent kinase subunit 85A http://flybase.org/reports/FBgn0037613 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 protein kinase binding ; GO:0019901 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 cyclin-dependent protein serine/threonine kinase activator activity ; GO:0061575 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 "endomitotic cell cycle ; GO:0007113 | inferred from mutant phenotype positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from biological aspect of ancestor with PANTHER:PTN000602176" SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 "CG9790, cks85A, BcDNA:GM01344, Cks85A, Cks" "IPR000789:Cyclin-dependent kinase, regulatory subunit" CG9790 11-Aug-17 DroID_v2017_08 "Drer\cks2, Drer\cks1b" Scer\CKS1 "Cele\cks-1, Cele\Y71G12B.27" "Xtro\cks1b, Xtro\cks2" "Mmus\Cks1b, Mmus\Cks1brt, Mmus\Cks2" "Hsap\CKS2, Hsap\CKS1B" "developmental rate defective,endomitotic cell cycle defective,mitotic cell cycle defective,heat sensitive,increased cell death,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,visible,viable" "embryonic/larval salivary gland,embryonic/larval brain,eye disc,heat sensitive,wing disc,wing hair,trichogen cell" FBgn0002427 l(3)F31 lethal (3) F31 http://flybase.org/reports/FBgn0002427 - gene - - - "l(3)31, l(3)F31" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,cell autonomous,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone,wing hair,abdomen,abdomen & macrochaeta | somatic clone" FBgn0000751 fs(1)A383 female sterile (1) A383 http://flybase.org/reports/FBgn0000751 - gene - - - "fs(1)1162, fs(1)A383" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,non-rescuable maternal effect,mitotic cell cycle defective" "blastoderm embryo,embryo" FBgn0004379 Klp67A Kinesin-like protein at 67A http://flybase.org/reports/FBgn0004379 "FBgn0044647, FBgn0046473, FBgn0060914" protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity motor activity ; GO:0003774 | inferred from sequence or structural similarity inferred from direct assay ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 spindle elongation ; GO:0051231 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype spindle assembly involved in male meiosis I ; GO:0007054 | inferred from mutant phenotype mitotic centrosome separation ; GO:0007100 | inferred from mutant phenotype male meiotic chromosome movement towards spindle pole ; GO:0016346 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype sister chromatid biorientation ; GO:0031134 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity generative cell mitosis ; GO:0055047 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from biological aspect of ancestor with PANTHER:PTN000649974 microtubule depolymerization ; GO:0007019 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype male meiosis I ; GO:0007141 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinetochore ; GO:0000776 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay mitotic spindle midzone ; GO:1990023 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay spindle microtubule ; GO:0005876 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay kinesin complex ; GO:0005871 | traceable author statement "KLP67A, DmKlp67A, CG10923, KRP67A, KLP3, 0427/05, l(3)S042705, Klp3, anon-WO0172774.120, anon-WO0140519.224, Klp67A, Kin-8, Klp67, klp67A, KIF 18A, KIF18A/B, klp67" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10923 11-Aug-17 DroID_v2017_08 "Drer\kif19, Drer\cenpe, Drer\si:dkey-26i13.8, Drer\kif22, Drer\kif18a" "Scer\KIP3, Scer\KIP2" Cele\klp-13 "Xtro\cenpe, Xtro\kif22, Xtro\kif19, Xtro\kif18a, Xtro\kif18b" "Mmus\Kif18b, Mmus\Kif18a, Mmus\Cenpe, Mmus\Kif19a, Mmus\Kif22" "Hsap\KIF19, Hsap\CENPE, Hsap\KIF18A, Hsap\KIF22, Hsap\KIF18B" " adult stage | male , adult stage | female , embryonic stage && larval stage && pupal stage " " testis

, ovary

" "male sterile,meiotic cell cycle defective,male,mitotic cell cycle defective,cytokinesis defective,female semi-sterile,fertile,partially lethal - majority die,recessive" "S2 cell-line,cytoplasmic microtubule,meiosis I | male29A6),meiosis II | male29A6),spermatocyte & aster | ectopic29A6),spermatocyte & astral microtubule29A6),spermatocyte & spindle | supernumerary29A6),spermatocyte & contractile ring29A6),spermatid & Nebenkern29A6),spermatid & nucleus29A6),spermatocyte & centrosome | supernumerary29A6),spermatocyte & condensed nuclear chromosome29A6),centrosome | blastoderm stage | maternal effect29A6),spindle | blastoderm stage | maternal effect29A6),mitotic anaphase B | blastoderm stage | maternal effect29A6),mitotic metaphase | blastoderm stage | maternal effect29A6),spindle microtubule | blastoderm stage | maternal effect29A6),spindle | embryonic stage 429A6),spermatocyte & nuclear chromosome29A6)[-],mitotic prometaphase & nuclear chromosome | male29A6)[-],meiotic anaphase II & condensed nuclear chromosome | male29A6)[-],spermatocyte & nuclear chromosome29A6),mitotic prometaphase & nuclear chromosome | male29A6),meiotic anaphase II & condensed nuclear chromosome | male29A6),spindle microtubule,astral microtubule,mitosis & nuclear chromosome,spindle pole,spindle" DRSC11205 E 1.197851509 -0.137680852 5.318506803 -2.263573812 0.193512512 -0.245765969 FBgn0000524 dx deltex http://flybase.org/reports/FBgn0000524 FBgn0026856 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR018123 Notch binding ; GO:0005112 | traceable author statement Notch binding ; GO:0005112 | inferred from physical interaction with UniProtKB:P07207 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model" positive regulation of Notch signaling pathway ; GO:0045747 | inferred from direct assay Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from direct assay imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from physical interaction with N Notch receptor processing ; GO:0007220 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | traceable author statement wing disc development ; GO:0035220 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay Notch signaling pathway ; GO:0007219 | traceable author statement positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with N cytoplasm ; GO:0005737 | inferred from direct assay "CG3929, dx, Dx, DMDELTEX" "IPR018123:WWE domain, subgroup, IPR001841:Zinc finger, RING-type, IPR004170:WWE domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3929 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-40c23.1, Drer\si:dkey-40c23.3, Drer\si:dkey-3h3.3, Drer\zgc:66440, Drer\LOC101885597, Drer\dtx4, Drer\si:ch211-119e14.2, Drer\dtx2, Drer\si:ch73-78o10.1, Drer\si:dkey-40c23.2" - - "Xtro\dtx1, Xtro\dtx3, Xtro\dtx2" "Mmus\Dtx1, Mmus\Dtx3, Mmus\Dtx2, Mmus\Dtx4, Mmus\Dtx3l" "Hsap\DTX3L, Hsap\DTX3, Hsap\UPK3B, Hsap\DTX4, Hsap\DTX2, Hsap\DTX1" " adult stage | female , embryonic stage--pupal stage , embryonic stage | early " "visible,viable,fertile,recessive,lethal,maternal effect,flightless,dominant,male sterile,heat sensitive,increased cell number,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "wing vein,wing margin bristle,wing,ommatidium,photoreceptor cell R3,ectopic,photoreceptor cell R4,interocellar bristle,ocellus,eye,microchaeta,macrochaeta,trichogen cell,tormogen cell,socket,thecogen cell,eo neuron,thorax & macrochaeta,distal,ocellar bristle,acrostichal bristle,wing margin,joint,leg,sensory mother cell,anterior crossvein,wing disc,ventral,microchaeta & mesothoracic tergumpnr-MD237" FBgn0022739 btl::Egfr btl::Egfr http://flybase.org/reports/FBgn0022739 - engineered_fusion_gene - - - "lambdatop, lambda-EGFR, lambda-TOP, lambda-DER, btl::Egfr, lambda-top, lambdaTop, top, lambdaTOP, EGFR[lambdatop], EGFR" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,increased cell size,somatic clone,decreased cell death,heat sensitive,neuroanatomy defective,homeotic,lethal - all die before end of first instar larval stage,some die during first instar larval stage,increased cell number,neoplasia" "wing,border follicle cell,chorion,wing vein,ectopic,dorsal appendage,egg,anterior,embryonic/first instar larval cuticle,ganglionic branch 1 | embryonic stage,mesothoracic tergum & macrochaeta | ectopic-C253,mitotic cell cycle | somatic clone,photoreceptor cell,somatic clone,wing vein L3,wing vein L4,tarsal segment,pleurum,ommatidium,muscle founder cell | embryonic stage,mesoderm,denticle belt,mesothoracic tergum,mesothoracic pleurum,wing margin & axon tractBx-MS1096,posterior,embryonic abdominal segment,supernumerary,eye disc,heat sensitive,actin filament & follicle cell,optic cartridge,secondary pigment cell,precursor,tertiary pigment cell,eye photoreceptor cell,wing disc,capitellum,wing margin bristle,dorsal branch primordium,embryonic trachea & cortical actin cytoskeletonbtl.PS,maternal effect,adult midgut precursor cell | third instar larval stage,larval inner optic anlage,muscle attachment site,lamellocyte | larval stage,glial cell,supernumerary | third instar larval stage,embryonic/larval brain | third instar larval stage,adult brain" FBgn0003142 Pri Prickly http://flybase.org/reports/FBgn0003142 - gene - - - "Pr, Pri" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,recessive,reduced,visible,lethal" "macrochaeta,posterior dorsocentral bristle,scutellar bristle" FBgn0025741 PlexA Plexin A http://flybase.org/reports/FBgn0025741 FBgn0062490 protein_coding_gene semaphorin receptor activity ; GO:0017154 | inferred from electronic annotation with InterPro:IPR031148 14-3-3 protein binding ; GO:0071889 | inferred from physical interaction with 14-3-3ε semaphorin receptor activity ; GO:0017154 | traceable author statement guanylate cyclase activator activity ; GO:0030250 | inferred from direct assay GTPase activator activity ; GO:0005096 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q6AWJ9 protein binding ; GO:0005515 | inferred from physical interaction with Sema2a heparin binding ; GO:0008201 | inferred from direct assay semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance ; GO:2000305 | inferred from genetic interaction with Sema1a inferred from genetic interaction with Rho1 sensory neuron axon guidance ; GO:0097374 | inferred from mutant phenotype inferred from genetic interaction with Sema2a Ras protein signal transduction ; GO:0007265 | inferred from direct assay axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | non-traceable author statement regulation of axon extension involved in axon guidance ; GO:0048841 | inferred from biological aspect of ancestor with PANTHER:PTN000504672 axon guidance ; GO:0007411 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from biological aspect of ancestor with PANTHER:PTN000504672 positive regulation of guanylate cyclase activity ; GO:0031284 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002165 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "PlexA1, PlexA, Plex1, CG11081, DPlexA, D-Plex A, BcDNA:GM05237, plexA, plex A, plex, lincRNA.927" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001627:Sema domain, IPR002165:Plexin repeat, IPR002909:IPT domain, IPR008936:Rho GTPase activation protein, IPR013548:Plexin, cytoplasmic RasGAP domain, IPR014756:Immunoglobulin E-set, IPR016201:PSI domain, IPR013783:Immunoglobulin-like fold, IPR031148:Plexin family" CG11081 11-Aug-17 DroID_v2017_08 "Drer\plxnb2b, Drer\plxnc1, Drer\mst1ra, Drer\si:ch211-127b11.1, Drer\plxnb2a, Drer\si:dkey-183c2.4, Drer\plxna1a, Drer\plxna3, Drer\plxnb1a, Drer\plxnb1b, Drer\plxna4, Drer\plxnb3, Drer\met, Drer\plxna1b, Drer\plxna2" - "Cele\plx-2, Cele\plx-1" "Xtro\plxnb3, Xtro\plxnc1, Xtro\mst1r, Xtro\plxna3, Xtro\plxna4, Xtro\plxnd1, Xtro\plxnb1, Xtro\met, Xtro\plxna1, Xtro\plxna2" "Mmus\Plxnb2, Mmus\Plxnb1, Mmus\Plxnb3, Mmus\Plxna1, Mmus\Plxna4, Mmus\Plxna2, Mmus\Met, Mmus\Plxna3, Mmus\Mst1r, Mmus\Plxnd1, Mmus\Plxnc1" "Hsap\PLXNA1, Hsap\PLXNA4, Hsap\PLXNB1, Hsap\PLXNA2, Hsap\PLXNA3, Hsap\PLXNB3, Hsap\PLXNC1, Hsap\MET, Hsap\PLXND1, Hsap\MST1R, Hsap\PLXNB2" " embryonic stage | early , embryonic stage | stage >=9 , embryonic stage " "

ubiquitous , embryonic central nervous system

, neuron

, myoblast

" "neuroanatomy defective,viable,visible" "eye photoreceptor cell | third instar larval stage,lamina | third instar larval stage,adult olfactory receptor neuron Or33c/85e,adult olfactory receptor neuron Or46a,adult olfactory receptor neuron Or42a,abdominal intersegmental nerve,presumptive embryonic/larval central nervous system,ventral nerve cord,longitudinal connective,abdominal segmental nerve,filamentous actin,macrochaeta,wing disc,longitudinal connective | embryonic stage,embryonic/larval central nervous system,intersegmental nerve,transverse nerve,fascicle,ectopic,central nervous system" FBgn0003129 Poxm Pox meso http://flybase.org/reports/FBgn0003129 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001523, InterPro:IPR009057" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001523 larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "CG9610, meso, poxm, P29, Pox-m, Poxm, POXM" "IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG9610 11-Aug-17 DroID_v2017_08 "Drer\pax1a, Drer\pax7a, Drer\pax3a, Drer\pax6b, Drer\pax2b, Drer\pax7b, Drer\pax9, Drer\arxb, Drer\pax2a, Drer\pax5, Drer\pax6a, Drer\arxa, Drer\pax10, Drer\pax8, Drer\pax1b" - "Cele\alr-1, Cele\pax-1, Cele\vab-3, Cele\pax-2, Cele\egl-38" "Xtro\pax7, Xtro\pax2, Xtro\pax3, Xtro\pax6, Xtro\pax1, Xtro\arx, Xtro\pax9, Xtro\pax5, Xtro\pax8" "Mmus\Arx, Mmus\Pax9, Mmus\Pax1, Mmus\Pax5, Mmus\Pax8, Mmus\Pax6, Mmus\Pax7, Mmus\Pax4, Mmus\Pax3, Mmus\Pax2" "Hsap\PAX4, Hsap\PAX1, Hsap\ARX, Hsap\PAX8, Hsap\PAX5, Hsap\PAX6, Hsap\PAX2, Hsap\PAX9, Hsap\PAX7, Hsap\PAX3" embryonic stage mesoderm | restricted

embryonic stage somatic mesoderm

"neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "dorsal multidendritic neuron ddaC,A1-7 ventral oblique muscle 2,A1-7 dorsal transverse muscle 1,embryonic/larval somatic muscle,A2-7 ventral transverse muscle 1,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,A1-7 ventral oblique muscle 1,A1-7 dorsal oblique muscle 3,A1-7 dorsal oblique muscle 4,A1-7 dorsal acute muscle 3,A1-7 lateral oblique muscle 1,A1-7 lateral transverse muscle 4,abdominal lateral adult muscle precursor cell,ectopic,eye,adult head,antenna,dorsal,dorso-lateral,A1-7 dorsal acute muscle 1,A1-7 lateral longitudinal muscle 1,A1-7 dorsal oblique muscle 5,abdominal dorsal adult muscle precursor cell,mesothoracic tergum" FBgn0000085 ano anomogenitals http://flybase.org/reports/FBgn0000085 - gene - - - "ang, ano" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,partially lethal - majority die,male sterile,viable,male,poor" "macrochaeta & head,macrochaeta & thorax,microchaeta & head,microchaeta & thorax,male genitalia,mesothoracic suture,macrochaeta & adult head,macrochaeta & adult thorax,microchaeta & adult thorax,microchaeta & adult abdomen" FBgn0011230 poe purity of essence http://flybase.org/reports/FBgn0011230 "FBgn0010161, FBgn0011240, FBgn0015532, FBgn0025867, FBgn0031982" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003126 calmodulin binding ; GO:0005516 | inferred from direct assay sperm individualization ; GO:0007291 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype perineurial glial growth ; GO:0042066 | inferred from mutant phenotype inferred from genetic interaction with eag inferred from genetic interaction with ine inferred from genetic interaction with Nf1 glial cell growth ; GO:0042065 | inferred from mutant phenotype P granule ; GO:0043186 | inferred from physical interaction with tud inferred from physical interaction with vas "push, Calo, CG14472, calo, ms(2)5970, 3420, ms(2)3420, ms(2)27C, ms(2)01659, poe, POE, POE_DROME, Poe, UBR4, POE/UBR4" "IPR025704:E3 ubiquitin ligase, UBR4, IPR017986:WD40-repeat-containing domain, IPR003126:Zinc finger, UBR-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical" CG14472 11-Aug-17 DroID_v2017_08 Drer\ubr4 - Cele\ubr-4 Xtro\ubr4 Mmus\Ubr4 Hsap\UBR4 adult stage "neuroanatomy defective,male sterile,recessive,viable,behavior defective,meiotic cell cycle defective,female fertile,uncoordinated,neurophysiology defective,body color defective" "synapse,bouton,spermatozoon,primary spermatocyte cyst,intersegmental nerve,anterior fascicle & synapse,surface associated glial cell,cystic bulge,mesothoracic tergum" DRSC03593 E -0.418358187 -1.427905976 -2.684670334 -0.127114069 -1.157997125 0.099671892 FBgn0015589 Apc APC-like http://flybase.org/reports/FBgn0015589 FBgn0039604 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VH90 beta-catenin binding ; GO:0008013 | inferred from direct assay axon guidance ; GO:0007411 | inferred from genetic interaction with Apc2 negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from genetic interaction with Apc2 single organismal cell-cell adhesion ; GO:0016337 | inferred from genetic interaction with Apc2 establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from genetic interaction with Apc2 positive regulation of protein complex assembly ; GO:0031334 | inferred from genetic interaction with dsh neuroblast proliferation ; GO:0007405 | inferred from genetic interaction with Apc2 imaginal disc pattern formation ; GO:0007447 | inferred from genetic interaction with Apc2 regulation of Wnt signaling pathway ; GO:0030111 | inferred from genetic interaction with Apc2 intracellular protein transport ; GO:0006886 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from genetic interaction with Apc2 negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with arm oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from genetic interaction with Apc2 negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with Apc2 medulla oblongata development ; GO:0021550 | inferred from genetic interaction with Apc2 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "APC, APC1, apc1, Apc1, apc, dAPC1, dAPC, DAPC, D-APC, dApc, CG1451, D-APC1, d-APC, Apc, APC-like, Dm APC1, apc 1, dapc1" "IPR000225:Armadillo, IPR009223:Adenomatous polyposis coli protein repeat, IPR009240:Adenomatous polyposis coli protein, 15 residue repeat, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR026818:Adenomatous polyposis coli (APC) family" CG1451 11-Aug-17 DroID_v2017_08 "Drer\apc2, Drer\apc" - Cele\apr-1 "Xtro\apc2, Xtro\apc" "Mmus\Apc, Mmus\Apc2" "Hsap\APC, Hsap\APC2" " embryonic stage | stage >13 , embryonic stage | early " " embryonic nervous system

, epidermis

" " embryonic stage | stage >12 , embryonic stage | late , larval stage | third instar " " embryonic nervous system

, neuron

, tendon cell

, ventral nerve cord commissure

, motor neuron

, longitudinal connective

" "increased cell death,viable,lethal,recessive,heat sensitive,cell lethal" "eye photoreceptor cell,hub cell,male germline stem cell,supernumerary,neuron & retina & pupa,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,photoreceptor cell,photoreceptor,male germline stem cell & spindle3450),male germline stem cell & centrosome3450)" FBgn0062590 Mod(var)1602 Mod(var)1602 http://flybase.org/reports/FBgn0062590 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1602, Mod(var)1602" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,partially lethal - majority die" FBgn0025637 SkpA SKP1-related A http://flybase.org/reports/FBgn0025637 "FBgn0026694, FBgn0026706, FBgn0028296, FBgn0040198, FBgn0066818, FBgn0066819, FBgn0066820" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with fsd ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000002736 protein binding ; GO:0005515 | inferred from physical interaction with mi protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with SGD:S000002736 centrosome duplication ; GO:0051298 | inferred from mutant phenotype positive regulation of mitotic cell cycle ; GO:0045931 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from direct assay negative regulation of insulin receptor signaling pathway ; GO:0046627 | inferred from genetic interaction with InR DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of centrosome duplication ; GO:0010824 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype inferred from genetic interaction with rpr inferred from genetic interaction with Diap1 negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with SGD:S000002736 SCF ubiquitin ligase complex ; GO:0019005 | non-traceable author statement "skpA, SkpA, CG16983, Skp1, spkA, dSkpA, EG:115C2.4, dSkp-1, l(1)G0389, l(1)G0109, dskpA, l(1)G0037, l(1)G0058, anon-WO03040301.238, anon-WO03040301.236, anon-WO03040301.234, dSKP1, Skp, SKP1, SKPA" "IPR011333:SKP1/BTB/POZ domain, IPR001232:S-phase kinase-associated protein 1-like, IPR016072:SKP1 component, dimerisation, IPR016073:SKP1 component, POZ domain, IPR016897:S-phase kinase-associated protein 1" CG16983 11-Aug-17 DroID_v2017_08 Drer\skp1 "Scer\SKP1, Scer\ELC1" "Cele\skr-9, Cele\skr-16, Cele\skr-21, Cele\skr-5, Cele\skr-1, Cele\skr-19, Cele\skr-13, Cele\skr-20, Cele\skr-14, Cele\skr-8, Cele\skr-4, Cele\skr-18, Cele\skr-6, Cele\skr-7, Cele\skr-3, Cele\skr-12, Cele\skr-17, Cele\skr-15, Cele\skr-2, Cele\skr-10" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 "neuroanatomy defective,maternal effect,viable,decreased cell death,conditional,radiation resistant,partially,size defective,increased cell death,lethal,recessive,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,fertile,somatic clone,mitotic cell cycle defective,heat sensitive" "NMJ bouton,maternal effect,embryonic/larval neuromuscular junction,prothoracic tarsal segment,joint,dorsal multidendritic neuron ddaC | pupal stage,wing,wing disc,melanotic mass,embryonic/larval digestive system,ganglion mother cell,gamma Kenyon cell,somatic clone,imaginal disc,embryonic/larval central nervous system,centrosome | supernumerary,chromatin,larval fat body & nucleus,larval foregut & nucleus,larval midgut & nucleus,larval hindgut & nucleus,NMJ bouton | larval stage,embryonic/larval neuroblast" DRSC18833 I 2.312574259 2.845588964 0.557065114 0.533257668 -0.76476465 0.833672225 FBgn0037375 kat-60L1 katanin p60-like 1 http://flybase.org/reports/FBgn0037375 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR028596 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule-severing ATPase activity ; GO:0008568 | inferred from biological aspect of ancestor with PANTHER:PTN000553509" microtubule severing ; GO:0051013 | inferred from sequence or structural similarity with NCBI_gi:3283072 neuron remodeling ; GO:0016322 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 katanin complex ; GO:0008352 | inferred from sequence or structural similarity with NCBI_gi:3283072 microtubule ; GO:0005874 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "DmCG1193, CG1193, kat-60L1" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR015415:Vps4 oligomerisation, C-terminal, IPR028596:Katanin p60 subunit A1" CG1193 11-Aug-17 DroID_v2017_08 "Drer\katnal1, Drer\katnal2, Drer\fignl1, Drer\katna1, Drer\vps4b, Drer\fign, Drer\spast" "Scer\VPS4, Scer\SAP1" "Cele\figl-1, Cele\mei-1, Cele\spas-1, Cele\vps-4" "Xtro\spast, Xtro\vps4a, Xtro\vps4b, Xtro\fign, Xtro\katna1, Xtro\fignl1" "Mmus\Katna1, Mmus\Vps4b, Mmus\Spast, Mmus\Vps4a, Mmus\Fign, Mmus\Katnal2, Mmus\Katnal1, Mmus\Fignl1" "Hsap\VPS4A, Hsap\VPS4B, Hsap\KATNAL1, Hsap\KATNA1, Hsap\SPAST, Hsap\KATNAL2" "short lived,viable,stress response defective,heat stress response defective,neuroanatomy defective,visible,fertile" "dendrite,class IV dendritic arborizing neuron,dendrite & dorsal multidendritic neuron ddaC | pupal stageppk.PG,dendriteppk.1.9,dorsal multidendritic neuron ddaC,chaeta,supernumerary,trichogen cell,dendrite & dorsal multidendritic neuron ddaC | pupal stage,microtubule & dorsal multidendritic neuron ddaC | pupal stage,dendrite & dorsal multidendritic neuron ddaC | pupal stageExel6145)" FBgn0011249 dolly-1 double loops of the Y 1 http://flybase.org/reports/FBgn0011249 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "ms(3)03817, P1784, dolly-1, ms(3)80" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" "Y chromosome loop,spermatozoon" FBgn0002749 mis misproportioned http://flybase.org/reports/FBgn0002749 - gene - - - mis - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,male,female,partially,male fertile,female fertile,reduced,body color defective" "adult abdomen,macrochaeta,microchaeta,male,female,tergite,trichome & adult abdomen | female,wing" FBgn0000442 Pkg21D "Protein kinase, cGMP-dependent at 21D" http://flybase.org/reports/FBgn0000442 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR002374, InterPro:IPR017441 cGMP-dependent protein kinase activity ; GO:0004692 | inferred from direct assay cGMP-dependent protein kinase activity ; GO:0004692 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "PKG-21D, dg1, PKG 21D, CG3324, DG1, PKG, cGMP, Pkg1, Dg1, Pkg21D, pkg21D" "IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR002374:cGMP-dependent kinase, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR014710:RmlC-like jelly roll fold, IPR017441:Protein kinase, ATP binding site" CG3324 11-Aug-17 DroID_v2017_08 "Drer\prkg1b, Drer\prkg1a, Drer\prkacaa, Drer\prkacba, Drer\prkacab, Drer\prkg2, Drer\prkg1l, Drer\prkx, Drer\LOC556339, Drer\si:dkey-121j17.5, Drer\prkacbb" "Scer\TPK3, Scer\TPK2, Scer\TPK1" "Cele\egl-4, Cele\pkg-2" "Xtro\prkx, Xtro\prkaca, Xtro\prkacb, Xtro\prkg2" "Mmus\Prkaca, Mmus\Prkg1, Mmus\Prkg2, Mmus\Prkacb, Mmus\Prkx" "Hsap\PRKG1, Hsap\PRKG2, Hsap\PRKX, Hsap\PRKACB, Hsap\PRKACA, Hsap\PRKACG" embryonic stage -- adult stage "cell migration defective,viable,visible,planar polarity defective" "embryonic/larval salivary gland,A1-7 ventral oblique muscle,mesothoracic tergum,A1-7 ventral acute muscle" FBgn0261868 lkd lackadaisical http://flybase.org/reports/FBgn0261868 gene - larval foraging behavior ; GO:0035177 | inferred from mutant phenotype - lkd - - 11-Aug-17 DroID_v2017_08 - - - - - - "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0037420 CG15597 - http://flybase.org/reports/FBgn0037420 protein_coding_gene - - - CG15597 IPR031903:Domain of unknown function DUF4766 CG15597 11-Aug-17 DroID_v2017_08 Drer\prnpa - - - "Mmus\Krtap21-1, Mmus\Krtap19-2, Mmus\Krtap6-2" - "viable,fertile,planar polarity defective" DRSC12283 K -0.601711519 0.52267631 -0.333738615 0.245724655 -1.543827833 -1.314560493 FBgn0052150 CG32150 - http://flybase.org/reports/FBgn0052150 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG15714, CG12712, CG32150" "IPR029071:Ubiquitin-related domain, IPR033593:N-terminal RASSF family" CG32150 11-Aug-17 DroID_v2017_08 "Drer\rassf9, Drer\LOC100003291, Drer\rassf10a, Drer\rassf7b, Drer\rassf7a" - - "Xtro\rassf10, Xtro\rassf9, Xtro\rassf7, Xtro\rassf8" "Mmus\Rassf10, Mmus\Rassf8, Mmus\Rassf7, Mmus\Rassf9" "Hsap\RASSF7, Hsap\RASSF8, Hsap\RASSF9, Hsap\RASSF10" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002561 l(1)sc lethal of scute http://flybase.org/reports/FBgn0002561 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from physical interaction with da protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from physical interaction with da sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from direct assay" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype ventral cord development ; GO:0007419 | traceable author statement neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype myoblast fate determination ; GO:0007518 | traceable author statement epithelial cell proliferation involved in Malpighian tubule morphogenesis ; GO:0061331 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay central nervous system development ; GO:0007417 | non-traceable author statement regulation of neurogenesis ; GO:0050767 | inferred from biological aspect of ancestor with PANTHER:PTN000358354 neurogenesis ; GO:0022008 | inferred from mutant phenotype" RNA polymerase II transcription factor complex ; GO:0090575 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 transcription factor complex ; GO:0005667 | inferred from physical interaction with da "L'Sc, L'sc, l'sc, T3, EG:198A6.2, CG3839, AS-T3, lsc, ASC-T3, AS-C T3, ascT3, sc/T3, l-sc, l(1)1Ba, l(1)sc, L(1)sc, bHLHc28, l[1]sc" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR015660:Achaete-scute transcription factor-related" CG3839 11-Aug-17 DroID_v2017_08 "Drer\tcf15, Drer\mespab, Drer\mespaa, Drer\ascl1b, Drer\tal1, Drer\msc, Drer\nhlh2, Drer\ptf1a, Drer\scxa, Drer\si:ch211-246m6.4, Drer\scxb, Drer\figla, Drer\tcf23, Drer\lyl1, Drer\tal2, Drer\tcf21, Drer\mespba, Drer\msgn1, Drer\hand2, Drer\ascl1a, Drer\tcf24" - "Cele\hlh-14, Cele\hlh-6, Cele\hlh-4, Cele\hlh-3" "Xtro\nhlh1, Xtro\ascl2, Xtro\lyl1, Xtro\tal1, Xtro\msgn1, Xtro\hand1, Xtro\scx, Xtro\mespb, Xtro\tcf15, Xtro\tcf21, Xtro\ptf1a, Xtro\msc, Xtro\hand2, Xtro\ascl3, Xtro\figla, Xtro\mespa" "Mmus\Tal2, Mmus\Msgn1, Mmus\Ptf1a, Mmus\Mesp2, Mmus\Ascl5, Mmus\Hand2, Mmus\Hand1, Mmus\Figla, Mmus\Ascl3, Mmus\Lyl1, Mmus\Ascl2, Mmus\Nhlh1, Mmus\Tcf21, Mmus\Ferd3l, Mmus\Ascl4, Mmus\Nhlh2, Mmus\Tcf15, Mmus\Mesp1, Mmus\Scx, Mmus\Ascl1, Mmus\Msc, Mmus\Tal1, Mmus\Tcf23" "Hsap\FIGLA, Hsap\TCF24, Hsap\ASCL5, Hsap\HAND2, Hsap\ASCL4, Hsap\TAL1, Hsap\LYL1, Hsap\MESP1, Hsap\MSC, Hsap\NHLH2, Hsap\MYF6, Hsap\TCF15, Hsap\HAND1, Hsap\ASCL2, Hsap\TCF21, Hsap\SCX, Hsap\NHLH1, Hsap\TAL2, Hsap\ASCL1, Hsap\PTF1A, Hsap\TCF23, Hsap\MESP2, Hsap\ASCL3, Hsap\MSGN1" " embryonic stage , embryonic stage | early , embryonic stage | stage 11,12 " " organism | pair rule

, posterior embryonic/larval midgut

, procephalic segment

, procephalic neuroblast

, optic lobe

, procephalic neurogenic region

, embryonic peripheral nervous system

,

ubiquitous , ventral midline

, epidermoblast

, Malpighian tubule

, labral segment

, embryonic stomatogastric nervous system

, embryonic ganglion mother cell

, neurogenic region

, neuroblast

, cephalic furrow

, stomodeum

, larval optic lobe | presumptive

, central nervous system

, ectoderm

" " embryonic stage , embryonic stage | stage 8-11 , embryonic stage | stage 9-11 , embryonic stage | stage >8 " " epidermoblast

{ + Dl* } , procephalic neurogenic region | restricted

, procephalic neuroblast | subset

, epidermoblast

, deuterocerebral neuroblast | subset

, neuroblast

{ + N* } , tritocerebral neuroblast | subset

, protocerebral neuroblast | subset

" "visible,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,lethal,neuroanatomy defective" "embryonic cardioblast,macrochaeta,microchaeta,sense organ,embryonic/larval somatic muscle,macrochaeta & scutellum455.2,scutellar bristle,ectopic,macrochaeta & abdominal sternite 1-537.4,macrochaeta & abdominal sternite 2-537.4,macrochaeta & abdominal sternite 3-537.4,macrochaeta & abdominal sternite 4-537.4,macrochaeta & abdominal sternite 5-537.4,macrochaeta & abdominal sternite 6-537.4,macrochaeta & pronotumh-540.3,macrochaeta & scutumh-540.3,macrochaeta & metathoracic laterotergiteh-540.3,macrochaeta & mesothoracic laterotergiteh-540.3,microchaeta & pronotumh-540.3,microchaeta & scutumh-540.3,microchaeta & metathoracic laterotergiteh-540.3,microchaeta & mesothoracic laterotergiteh-540.3,wing vein,macrochaeta & wing564.2,scutellum & microchaetaptc-559.1,sensory mother cell & dorsal mesothoracic dip-md544,embryonic/larval maxillary chordotonal organ with two scolopidia,monoscolopidial chordotonal organ,lateral ventral neurectoderm,medial ventral neurectoderm,intermediate ventral neurectoderm,stage 1 neuroblast,ganglion mother cell" FBgn0000273 Pka-C1 "Protein kinase, cAMP-dependent, catalytic subunit 1" http://flybase.org/reports/FBgn0000273 "FBgn0000353, FBgn0010695" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 protein binding ; GO:0005515 | inferred from physical interaction with Dere\Pka-R2 cAMP-dependent protein kinase activity ; GO:0004691 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with slo protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity sprouting of injured axon ; GO:0048682 | inferred from mutant phenotype learning ; GO:0007612 | non-traceable author statement regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from genetic interaction with hid oogenesis ; GO:0048477 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype anesthesia-resistant memory ; GO:0007615 | inferred from mutant phenotype regulation of bicoid mRNA localization ; GO:0008359 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | non-traceable author statement cAMP-mediated signaling ; GO:0019933 | non-traceable author statement learning or memory ; GO:0007611 | non-traceable author statement cAMP-mediated signaling ; GO:0019933 | traceable author statement modulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype rhythmic behavior ; GO:0007622 | inferred from mutant phenotype rhythmic behavior ; GO:0007622 | traceable author statement negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from genetic interaction with Su(fu) behavioral response to ethanol ; GO:0048149 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from mutant phenotype olfactory learning ; GO:0008355 | non-traceable author statement compound eye development ; GO:0048749 | non-traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | non-traceable author statement thermosensory behavior ; GO:0040040 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | traceable author statement anterior/posterior pattern specification, imaginal disc ; GO:0007448 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement olfactory learning ; GO:0008355 | inferred from mutant phenotype memory ; GO:0007613 | non-traceable author statement" cell body ; GO:0044297 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cAMP-dependent protein kinase complex ; GO:0005952 | inferred from sequence or structural similarity dendrite ; GO:0030425 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "PKA, PKA CI, DC0, DCO, pka-C1, Cos1, pka-c1, pka, PKAc, dPKA, Pka, Pka-C, PKAcA, pkA, PKA Cl, CG4379, pKA, 6353, PKA-C1, Dc0, l(2)01272, C, dco, Cos-1, Dco, dcO, Cos, l(2)cos[[1]], cos1, l(2)s4402, Dcpk, CdkA, Pka-C1, PkaC1, pka C1, PKAC1, dc0" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG4379 11-Aug-17 DroID_v2017_08 "Drer\prkacaa, Drer\prkx, Drer\prkg2, Drer\prkacbb, Drer\prkacab, Drer\sgk2b, Drer\prkg1b, Drer\prkacba, Drer\LOC556339" "Scer\TPK2, Scer\YPK3, Scer\TPK1, Scer\TPK3" "Cele\kin-1, Cele\F47F2.1" "Xtro\prkx, Xtro\prkg2, Xtro\prkaca, Xtro\prkacb" "Mmus\Prkacb, Mmus\Prkx, Mmus\Prkg1, Mmus\Prkg2, Mmus\Prkaca" "Hsap\PRKACB, Hsap\PRKG2, Hsap\PRKG1, Hsap\PRKX, Hsap\PRKACA, Hsap\PRKACG" " adult stage , adult stage && oogenesis stage , embryonic stage -- adult stage " " optic lobe

, mushroom body

, germarium

, oocyte

, adult brain

, thoracico-abdominal ganglion

, nurse cell

" " adult stage | female , adult stage , larval stage | third instar , embryonic stage -- adult stage , adult stage | male " " ovary

, mushroom body beta-lobe

, larval brain

, mushroom body alpha-lobe

, mushroom body

, mushroom body gamma-lobe

, calyx of mushroom body

, testis

, dorsal mesothoracic disc

, male accessory gland

" "lethal,recessive,wild-type,locomotor rhythm defective,viable,visible,circadian rhythm defective,behavior defective,thermotaxis behavior defective,planar polarity defective,somatic clone,female sterile,partially lethal - majority die,cell non-autonomous,chemical sensitive,dominant,memory defective,lethal - all die before end of embryonic stage,germline clone,some die during embryonic stage,partially lethal - majority live,heat sensitive,cold sensitive,temperature conditional,lethal - all die before end of P-stage,decreased cell death,neurophysiology defective,lethal - all die during third instar larval stage,smell perception defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,fertile,tumorigenic,developmental rate defective,partially" "wing,anterior compartment,scutum,leg,Malpighian tubule,eye disc,somatic clone,eye equator,ectopic,ommatidium,morphogenetic furrow,egg,eye,eye-antennal disc,cell non-autonomous,follicle cell,border follicle cell,polar follicle cell,egg chamber,germline clone,nurse cell,oocyte,germline cell,oocyte & microtubule | germ-line clone,microtubule organizing center | germline clone,sex comb,haltere,antenna,adult abdomen & cuticle | anterior compartment,adult abdomen & macrochaeta | anterior compartment,adult abdomen & microchaeta | anterior compartment,eye photoreceptor cell,mesothoracic tergum & macrochaeta | somatic clone | cell non-autonomous,macrochaeta,neuromuscular junction,neuron,female gonopod,gonopod thorn bristle,epiproct,hypoproct,spermathecum,genital arch,lateral plate,clasper,penis,anal plate,wing disc,wing vein L3,adult thorax,mesothoracic tergum,anterior,wing vein,melanotic mass,adult,wing margin bristle" DRSC03399 I -0.280794596 -2.390903532 0.083802859 -0.221914834 -0.923124491 0.056834023 FBgn0035142 Hipk Homeodomain interacting protein kinase http://flybase.org/reports/FBgn0035142 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein kinase activity ; GO:0004672 | inferred from direct assay beta-catenin binding ; GO:0008013 | inferred from physical interaction with arm transcription factor binding ; GO:0008134 | inferred from physical interaction with pan protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with SGD:S000003677" protein stabilization ; GO:0050821 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of gene expression ; GO:0010628 | inferred from genetic interaction with nito positive regulation of hippo signaling ; GO:0035332 | inferred from mutant phenotype inferred from genetic interaction with wts inferred from genetic interaction with yki inferred from physical interaction with yki compound eye development ; GO:0048749 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with Dl inferred from genetic interaction with gro inferred from genetic interaction with H inferred from genetic interaction with N imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype organ growth ; GO:0035265 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of programmed cell death ; GO:0043067 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "HIPK, CG17090, dhipk2, Hipk, HIPK2, hipk, DHIPK2, hipK" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG17090 11-Aug-17 DroID_v2017_08 "Drer\hipk3a, Drer\zgc:172180, Drer\hipk1a, Drer\dyrk4, Drer\hipk3b, Drer\si:ch211-160o17.4, Drer\dyrk2, Drer\hipk2, Drer\dyrk1aa, Drer\dyrk1ab, Drer\mast1b, Drer\dyrk1b" "Scer\MKK2, Scer\YAK1" "Cele\hpk-1, Cele\mbk-1, Cele\mbk-2" "Xtro\dyrk3, Xtro\dyrk1a, Xtro\hipk3, Xtro\hipk2, Xtro\dyrk2, Xtro\hipk1" "Mmus\Dyrk1b, Mmus\Dyrk2, Mmus\Dyrk3, Mmus\Dyrk4, Mmus\Wnk1, Mmus\Hipk4, Mmus\Hipk3, Mmus\Hipk1, Mmus\Dyrk1a, Mmus\Hipk2" "Hsap\DYRK4, Hsap\DYRK1A, Hsap\HIPK2, Hsap\DYRK3, Hsap\HIPK1, Hsap\DYRK1B, Hsap\HIPK3, Hsap\HIPK4, Hsap\DYRK2" "gravitaxis defective,visible,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,size defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable,fertile,female sterile,cell death defective,somatic clone,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage" "eye,ectopic,ventral,eye photoreceptor cell,somatic clone,wing vein L2,posterior crossvein,wing margin,eye disc,ventral wing blade,wing disc | third instar larval stage,wing vein,intersegmental nerve,wing,imaginal disc epithelial cell,central nervous system,ommatidium" FBgn0036144 GlcAT-P GlcAT-P http://flybase.org/reports/FBgn0036144 protein_coding_gene "N-acetyllactosamine beta-1,3-glucuronosyltransferase activity ; GO:0046987 | inferred from direct assay galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity ; GO:0046989 | inferred from direct assay asioloorosomucoid beta-1,3-glucuronosyltransferase activity ; GO:0046988 | inferred from direct assay galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ; GO:0015018 | inferred from direct assay" glycosphingolipid biosynthetic process ; GO:0006688 | non-traceable author statement peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype chondroitin sulfate proteoglycan biosynthetic process ; GO:0050650 | inferred from biological aspect of ancestor with PANTHER:PTN000855563 glycoprotein biosynthetic process ; GO:0009101 | non-traceable author statement carbohydrate metabolic process ; GO:0005975 | inferred from biological aspect of ancestor with PANTHER:PTN000096174 proteoglycan biosynthetic process ; GO:0030166 | non-traceable author statement chondroitin sulfate metabolic process ; GO:0030204 | inferred from biological aspect of ancestor with PANTHER:PTN000855563 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005027 "DmGlcAT-BSII, CG6207, DGlcAT-P, GlcAT-P, dGlcAT-BSII, dGlcAT-P" "IPR029044:Nucleotide-diphospho-sugar transferases, IPR005027:Glycosyl transferase, family 43" CG6207 11-Aug-17 DroID_v2017_08 "Drer\b3gat3, Drer\b3gat2, Drer\b3gat1b, Drer\b3gat1a" - "Cele\glct-3, Cele\glct-1, Cele\glct-4, Cele\glct-5, Cele\glct-6, Cele\sqv-8, Cele\glct-2" "Xtro\b3gat1, Xtro\b3gat3, Xtro\b3gat2" "Mmus\B3gat2, Mmus\B3gat1, Mmus\B3gat3" "Hsap\B3GAT2, Hsap\B3GAT3, Hsap\B3GAT1" embryonic stage -- adult stage "neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" "ventral nerve cord,leg,wing,VUM neuron,embryonic/larval peripheral nervous system,peripheral glial cell" DRSC10604 I -1.582716408 3.612300375 -0.77375302 0.406575206 0.703467433 1.331497757 FBgn0039907 lgs legless http://flybase.org/reports/FBgn0039907 protein_coding_gene RNA polymerase II transcription coactivator activity ; GO:0001105 | contributes_to inferred from physical interaction with arm inferred from physical interaction with pygo "transcription, DNA-templated ; GO:0006351 | inferred from physical interaction with UniProtKB:P18824 inferred from physical interaction with UniProtKB:Q9V9W8 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from physical interaction with UniProtKB:P18824 inferred from physical interaction with UniProtKB:Q9V9W8 segment polarity determination ; GO:0007367 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "lgs, Lgs, Lgl, CG2041, BCL9, Dm Lgs" "IPR024670:B-cell lymphoma 9, beta-catenin binding domain" CG2041 11-Aug-17 DroID_v2017_08 "Drer\bcl9, Drer\pygo2, Drer\bcl9l, Drer\pygo1" - Cele\C02B10.5 - "Mmus\Pygo2, Mmus\Pygo1, Mmus\Bcl9, Mmus\Bcl9l" "Hsap\PYGO2, Hsap\BCL9L, Hsap\PYGO1, Hsap\BCL9" "visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,recessive,germline clone,segment polarity phenotype,cell lethal,cell autonomous,somatic clone,viable" "mesothoracic tergum,ectopic,wing,sternite,pleurum,leg,antenna,embryonic/first instar larval cuticle,denticle,imaginal disc,maternal effect,wing margin" FBgn0037924 CG14712 - http://flybase.org/reports/FBgn0037924 protein_coding_gene nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 neurogenesis ; GO:0022008 | inferred from mutant phenotype protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000573960 - CG14712 IPR026054:Nuclear pore complex protein CG14712 11-Aug-17 DroID_v2017_08 "Drer\pom121, Drer\nup153" Scer\NUP1 Cele\npp-7 Xtro\nup153 "Mmus\Pom121, Mmus\Nup153, Mmus\Pom121l2" "Hsap\POM121L2, Hsap\POM121, Hsap\NUP153, Hsap\POM121C, Hsap\NPAP1, Hsap\POM121L12" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC14935 I 2.867307026 0.927766685 0.926790328 -1.294797621 -0.695530517 -1.341958083 FBgn0040292 Pth Pth http://flybase.org/reports/FBgn0040292 gene - - - Pth - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant" "wing,ectopic,scutum" FBgn0001253 ImpE1 Ecdysone-inducible gene E1 http://flybase.org/reports/FBgn0001253 "FBgn0035884, FBgn0035885, FBgn0052356, FBgn0062446" protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc eversion ; GO:0007561 | traceable author statement extrinsic component of membrane ; GO:0019898 | traceable author statement "IMP-E1, CG7116, Imp-E1, CT33103, CT22003, CG13668, CG32356, BcDNA:RE39082, ImpE1" "IPR006149:EB domain, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR032675:Leucine-rich repeat domain, L domain-like, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG32356 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-258f14.3, Drer\sorl1, Drer\scospondin, Drer\lrp1ba, Drer\akap12b, Drer\lrp1ab, Drer\LOC100536757, Drer\egf, Drer\lrp1bb, Drer\ldlra, Drer\lrp8, Drer\ldlrad3, Drer\bod1l1" "Scer\APM2, Scer\APM3, Scer\APM1" Cele\H11E01.3 "Xtro\lrp2, Xtro\lrp1, Xtro\sorl1, Xtro\lrp4, Xtro\ldlrad3" "Mmus\Lrp3, Mmus\Cd320, Mmus\Lrp2, Mmus\Lrp4, Mmus\Sorl1, Mmus\Ldlrad3, Mmus\Sspo, Mmus\Lrp1b, Mmus\Lrp1" "Hsap\SORL1, Hsap\LRP5L, Hsap\CD320, Hsap\LRP2, Hsap\LRP1, Hsap\LRP1B, Hsap\LRP3, Hsap\LRP4, Hsap\LDLRAD3" "viable,fertile,lethal" FBgn0065270 l(2)SH2059 lethal (2) SH2059 http://flybase.org/reports/FBgn0065270 gene - - - "l(2)SH2059, l(2)SH2 2059" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0011080 l(1)Q36 lethal (1) Q36 http://flybase.org/reports/FBgn0011080 FBgn0010210 gene - - - l(1)Q36 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040066 wds will die slowly http://flybase.org/reports/FBgn0040066 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCH5 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from direct assay positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from direct assay haltere development ; GO:0007482 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q9VCH5 neurogenesis ; GO:0022008 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from genetic interaction with UniProtKB:Q9VCH5 chromatin remodeling ; GO:0006338 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs microtubule associated complex ; GO:0005875 | inferred from direct assay NSL complex ; GO:0044545 | inferred from direct assay MLL3/4 complex ; GO:0044666 | inferred from direct assay Set1C/COMPASS complex ; GO:0048188 | inferred from direct assay MLL1/2 complex ; GO:0044665 | inferred from sequence or structural similarity with HGNC:12757 nucleus ; GO:0005634 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from physical interaction with Ada2a Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay "wds, l(1)zw8, EG:BACR25B3.7, CG17437, l(1)G0251, l(1)3Ad, zw-8, zw8, l(1)16-94, WDS, Wds, WDR5, WD5" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG17437 11-Aug-17 DroID_v2017_08 "Drer\wsb2, Drer\wdr90, Drer\ahi1, Drer\ambra1a, Drer\wdr5, Drer\cfap52" "Scer\YMR102C, Scer\UTP13, Scer\TUP1, Scer\SWD3, Scer\PRP4, Scer\SPT8" "Cele\wdr-5.3, Cele\wdr-5.2, Cele\Y53C12B.1, Cele\wdr-5.1, Cele\B0280.9" "Xtro\wdr90, Xtro\ambra1, Xtro\wdr5" "Mmus\Ahi1, Mmus\Wdr5, Mmus\Wdr90, Mmus\Tbl3, Mmus\Ambra1, Mmus\Nwd1, Mmus\Wsb1, Mmus\Wdr5b, Mmus\Wsb2, Mmus\Wdr95, Mmus\Cfap52, Mmus\Wdr38" "Hsap\WDR90, Hsap\WDR5B, Hsap\AHI1, Hsap\WDR5, Hsap\CFAP52, Hsap\WDR38, Hsap\WDR88, Hsap\WSB2, Hsap\TBL3" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,cell lethal,germline clone,heat sensitive,female sterile,visible,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "egg,germline clone,female reproductive system,macrochaeta,posterior vertical bristle,posterior scutellar bristle,wing,wing vein,wing vein L2,wing vein L3,wing vein L5,ovary,ganglion mother cell" DRSC18852 E -1.048100407 0.009038524 0.007493099 -3.005349953 -0.441487964 0.136647376 FBgn0005254 l(3)SG73 lethal (3) SG73 http://flybase.org/reports/FBgn0005254 - gene - - - l(3)SG73 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0052298 CG32298 - http://flybase.org/reports/FBgn0052298 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs10a03, CG32298" - CG32298 11-Aug-17 DroID_v2017_08 - - - - - - "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0031261 nAChRbeta3 nicotinic Acetylcholine Receptor beta3 http://flybase.org/reports/FBgn0031261 protein_coding_gene acetylcholine-gated cation channel activity ; GO:0022848 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006029, InterPro:IPR006201 sleep ; GO:0030431 | inferred from expression pattern synaptic transmission, cholinergic ; GO:0007271 | inferred from sequence or structural similarity with nAChRβ2" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006201 postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity" "CG11822, nAcR-21Beta, nAChR, Dbeta3, CT33131, nAcRbeta-21C, nAChRbeta3, nAChR-beta21C" "IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG11822 11-Aug-17 DroID_v2017_08 "Drer\chrnd, Drer\htr3b, Drer\LOC798522, Drer\chrna9, Drer\si:ch211-39a7.1, Drer\chrng, Drer\chrna1, Drer\chrnb1l, Drer\chrnb3b, Drer\LOC101882451, Drer\chrnb2b, Drer\chrnb1, Drer\si:ch211-256e16.4, Drer\chrna10a, Drer\chrnb2l, Drer\chrna3, Drer\chrna2a, Drer\chrna4b, Drer\chrne, Drer\chrnb3a, Drer\htr3a, Drer\chrnb4, Drer\chrna7, Drer\chrna2b, Drer\chrna5, Drer\chrna6" - "Cele\pbo-5, Cele\acr-10, Cele\lgc-23, Cele\lgc-8, Cele\lgc-30, Cele\acr-23, Cele\lgc-14, Cele\lgc-21, Cele\lgc-6, Cele\eat-2, Cele\lgc-31, Cele\acr-17, Cele\lgc-9, Cele\acr-24, Cele\cup-4, Cele\lgc-15, Cele\acr-5, Cele\lgc-13, Cele\acr-7, Cele\acr-16, Cele\lgc-18, Cele\lgc-7, Cele\acr-11, Cele\acr-20, Cele\deg-3, Cele\W10G11.17, Cele\lgc-19, Cele\acr-9, Cele\lgc-5, Cele\lgc-16, Cele\lgc-29, Cele\acr-25, Cele\lgc-12, Cele\lgc-11, Cele\acr-15, Cele\lgc-24, Cele\pbo-6, Cele\lgc-1, Cele\lgc-26, Cele\des-2, Cele\lgc-10, Cele\acr-19, Cele\lgc-25, Cele\acr-18, Cele\acr-14, Cele\lgc-17" "Xtro\chrnb2, Xtro\chrna1.2, Xtro\chrnd, Xtro\chrna6, Xtro\chrna1, Xtro\chrna2, Xtro\chrnb3, Xtro\chrne, Xtro\chrna5, Xtro\chrna7, Xtro\chrng, Xtro\chrna9" "Mmus\Htr3a, Mmus\Chrnb1, Mmus\Chrna1, Mmus\Chrna7, Mmus\Chrnb2, Mmus\Chrne, Mmus\Chrnd, Mmus\Chrna2, Mmus\Chrna5, Mmus\Chrna10, Mmus\Chrna3, Mmus\Chrna4, Mmus\Chrna6, Mmus\Chrnb3, Mmus\Chrna9, Mmus\Chrng, Mmus\Chrnb4, Mmus\Htr3b" "Hsap\CHRNA1, Hsap\HTR3B, Hsap\CHRNE, Hsap\HTR3D, Hsap\CHRNA4, Hsap\CHRNB1, Hsap\CHRNA2, Hsap\CHRNB3, Hsap\CHRND, Hsap\ZACN, Hsap\CHRNB4, Hsap\HTR3E, Hsap\CHRNA10, Hsap\CHRNB2, Hsap\CHRNA7, Hsap\CHRNA5, Hsap\CHRNG, Hsap\HTR3C, Hsap\HTR3A, Hsap\CHRNA3, Hsap\CHRFAM7A, Hsap\CHRNA6, Hsap\CHRNA9" viable FBgn0030224 CG12637 - http://flybase.org/reports/FBgn0030224 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG12637 IPR009961:Protein of unknown function DUF1487 CG12637 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0000256 capu cappuccino http://flybase.org/reports/FBgn0000256 FBgn0031576 protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity microtubule binding ; GO:0008017 | inferred from mutant phenotype actin filament-based process ; GO:0030029 | inferred from direct assay pole plasm RNA localization ; GO:0007316 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | traceable author statement oogenesis ; GO:0048477 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | non-traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype actin nucleation ; GO:0045010 | inferred from direct assay pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement actin filament ; GO:0005884 | inferred from electronic annotation with InterPro:IPR001265 cytoplasm ; GO:0005737 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "capu, Capu, CG3399, capp, CG15420" "IPR001265:Formin homology family, Cappuccino subfamily, IPR015425:Formin, FH2 domain" CG3399 11-Aug-17 DroID_v2017_08 "Drer\fhdc4, Drer\fmn2b, Drer\daam1b, Drer\fmn2a, Drer\daam2, Drer\grid2ipb, Drer\LOC101882656, Drer\si:ch1073-209e23.1, Drer\fmn1, Drer\fhdc3, Drer\fhdc2, Drer\grid2ipa, Drer\daam1a, Drer\LOC100148950, Drer\fhdc1" - Cele\inft-2 "Xtro\fmn2, Xtro\grid2ip, Xtro\fhdc1, Xtro\daam1, Xtro\fmn1, Xtro\inf2" "Mmus\Daam2, Mmus\Grid2ip, Mmus\Fmn1, Mmus\Inf2, Mmus\Daam1, Mmus\Fmn2, Mmus\Fhdc1" "Hsap\INF2, Hsap\DAAM2, Hsap\DAAM1, Hsap\FMN1, Hsap\GRID2IP, Hsap\FMN2, Hsap\FHDC1" " larval stage | third instar , oogenesis stage , adult stage | female , oogenesis stage | stage S4-9 , adult stage | male , oogenesis stage | stage S4-11 , embryonic stage | 0-24hr , oogenesis stage | stage S1-13 " " germarium region 2a && germarium region 2b && germarium region 3

, ovary

, oocyte

, follicle cell

, nurse cell

" "viable,fertile,female sterile,lethal,maternal effect,recessive,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,dorsal/ventral axis specification defective,female semi-sterile" "embryonic abdominal segment,dorsal appendage,pole cell,pole granule,chorion | maternal effect,embryo,maternal effect,embryonic abdomen,egg,egg chamber,follicle cell,blastoderm embryo,germline clone,posterior,stage S8 oocyte,microtubule,filamentous actin | oogenesis stage S9,oocyte,oocyte nucleus,chorion,actin filament,nurse cell ring canal,actin filamentnos.UTR.THsimVP16, capuI706A.UAS.PT.RA.TAvicGFP,nurse follicle cell,filamentous actin | oogenesis stage S9ed1),actin filamentnos.UTR.THsimVP16, capu1" FBgn0036726 QIL1 QIL1 http://flybase.org/reports/FBgn0036726 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype cristae formation ; GO:0042407 | inferred from mutant phenotype regulation of cristae formation ; GO:1903850 | inferred from mutant phenotype - "QIL1, CG7603" IPR026769:MICOS complex subunit Mic13 CG7603 11-Aug-17 DroID_v2017_08 Drer\si:dkey-78l4.14 - Cele\W04C9.2 - Mmus\2410015M20Rik Hsap\C19orf70 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0013510 l(1)VA624 lethal (1) VA624 http://flybase.org/reports/FBgn0013510 - gene - - - l(1)VA624 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0265174 PIG-V Phosphatidylinositol glycan anchor biosynthesis class V http://flybase.org/reports/FBgn0265174 protein_coding_gene dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity ; GO:0004584 | inferred from electronic annotation with InterPro:IPR007315 mannosyltransferase activity ; GO:0000030 | inferred from biological aspect of ancestor with PANTHER:PTN000279676 mannosyltransferase activity ; GO:0000030 | inferred from sequence or structural similarity with UniProtKB:Q9NUD9 mannosyltransferase activity ; GO:0000030 | inferred from sequence orthology with HGNC:26031 "regulation of Golgi to plasma membrane protein transport ; GO:0042996 | inferred from mutant phenotype protein insertion into ER membrane by GPI attachment sequence ; GO:0045052 | inferred by curator from GO:0000030,GO:0051205 positive regulation of protein exit from endoplasmic reticulum ; GO:0070863 | inferred from mutant phenotype rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with UniProtKB:Q9NUD9 protein insertion into membrane ; GO:0051205 | inferred from mutant phenotype GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000279676" endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with UniProtKB:Q9NUD9 mannosyltransferase complex ; GO:0031501 | inferred from biological aspect of ancestor with PANTHER:PTN000279676 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000279676 "CG6657, gpi-mt2, PIG-V, CG44239" IPR007315:GPI mannosyltransferase 2 CG44239 11-Aug-17 DroID_v2017_08 Drer\pigv Scer\GPI18 Cele\pigv-1 Xtro\pigv Mmus\Pigv Hsap\PIGV "lethal,recessive,lethal - all die before end of larval stage,viable,neuroanatomy defective,progressive" "rhabdomere,somatic clone,rhabdomere microvillus | somatic clone,progressive,eye photoreceptor cell" FBgn0028142 l(3)S047418 lethal (3) S047418 http://flybase.org/reports/FBgn0028142 gene - - - "0474/18, l(3)S047418" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0060734 l(3)S067205b lethal (3) S067205b http://flybase.org/reports/FBgn0060734 gene - - - "0672/05, l(3)S067205b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037218 aux auxilin http://flybase.org/reports/FBgn0037218 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271 protein kinase activity ; GO:0004672 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271 sperm individualization ; GO:0007291 | inferred from mutant phenotype negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype synaptic vesicle uncoating ; GO:0016191 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype" Golgi stack ; GO:0005795 | inferred from direct assay vesicle ; GO:0031982 | inferred from biological aspect of ancestor with PANTHER:PTN000571055 "auxilin, CG1107, GAK, anon-WO0118547.393, aux, auxillin, Aux, dAux, Auxillin/DNAJC6, DNAJC6" "IPR000719:Protein kinase domain, IPR001623:DnaJ domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR000008:C2 domain, IPR014020:Tensin phosphatase, C2 domain, IPR029023:Tensin-type phosphatase domain, IPR029021:Protein-tyrosine phosphatase-like" CG1107 11-Aug-17 DroID_v2017_08 "Drer\ptenb, Drer\tns2b, Drer\tns2a, Drer\bmp2k, Drer\tns1a, Drer\gak, Drer\dnajc6, Drer\si:ch211-191a24.3, Drer\aak1a, Drer\tpte, Drer\tns1b, Drer\aak1b" "Scer\PRK1, Scer\TEP1, Scer\TDA1, Scer\SWA2, Scer\AKL1, Scer\ARK1" "Cele\tag-257, Cele\dnj-25" "Xtro\tns2, Xtro\tns1, Xtro\pten, Xtro\aak1, Xtro\tpte2, Xtro\dnajc6, Xtro\gak, Xtro\bmp2k" "Mmus\Pten, Mmus\Gak, Mmus\Bmp2k, Mmus\Tns2, Mmus\Tns3, Mmus\Aak1, Mmus\Dnajc6, Mmus\Tns1, Mmus\Tpte" "Hsap\TPTE, Hsap\TNS2, Hsap\AAK1, Hsap\DNAJC6, Hsap\BMP2K, Hsap\PTEN, Hsap\TNS1, Hsap\GAK, Hsap\TPTE2, Hsap\TNS3" "female sterile,male sterile,neuroanatomy defective,maternal effect,viable,visible,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,cold sensitive,lethal - all die before end of pupal stage,some die during pupal stage" "wing vein,eye,heat sensitive,ommatidium,outer photoreceptor cell,supernumerary,vibrissae,anterior sternopleural bristle,ectopic,scutellar bristle,notopleural bristle,posterior crossvein,inner photoreceptor cell,ventral nerve cord,maternal effect,presumptive embryonic/larval peripheral nervous system,eye photoreceptor cell,sternopleural bristle,cystic bulge,individualization stage spermatid,male germline stem cell,embryo,epidermis,wing,wing blade,ommatidial precursor cluster,somatic clone" FBgn0019972 Drice Death related ICE-like caspase http://flybase.org/reports/FBgn0019972 - protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity with HGNC:1504 inferred from sequence or structural similarity with HGNC:1507 BIR domain binding ; GO:1990525 | inferred from physical interaction with Diap2 inferred from physical interaction with Diap1 cysteine-type endopeptidase activity involved in apoptotic process ; GO:0097153 | inferred from direct assay cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:0097200 | inferred from direct assay cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway ; GO:2001269 | inferred from direct assay salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype regulation of retinal cell programmed cell death ; GO:0046668 | non-traceable author statement response to X-ray ; GO:0010165 | inferred from mutant phenotype apoptotic process ; GO:0006915 | traceable author statement sterol regulatory element binding protein cleavage ; GO:0035103 | inferred from direct assay programmed cell death ; GO:0012501 | inferred from mutant phenotype programmed cell death ; GO:0012501 | inferred from direct assay positive regulation of compound eye retinal cell programmed cell death ; GO:0046672 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from direct assay nurse cell apoptotic process ; GO:0045476 | inferred from genetic interaction with Dcp-1 programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "Drice, drICE, drice, DrICE, DRICE, ICE, CG7788, DrIce, ice, caspase 3, Drive, crice, Ice, drIce" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR015917:Peptidase C14A, caspase catalytic domain, IPR016129:Peptidase family C14A, His active site, IPR029030:Caspase-like domain, IPR033139:Peptidase family C14A, cysteine active site" CG7788 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-195h23.3, Drer\caspa, Drer\casp3a, Drer\casp3b, Drer\zgc:171731, Drer\caspxa, Drer\casp8, Drer\pea15, Drer\casp6l1, Drer\LOC100331324, Drer\casp8l1, Drer\casp2, Drer\casp6, Drer\LOC101886133, Drer\gbp3, Drer\cflara, Drer\zgc:194469, Drer\casp9, Drer\caspbl, Drer\casp6l2, Drer\caspb, Drer\casp8l2, Drer\si:dkey-103e21.5, Drer\casp7, Drer\LOC798445" - "Cele\csp-1, Cele\ced-3" "Xtro\casp1, Xtro\casp9, Xtro\casp2, Xtro\casp6, Xtro\LOC733553, Xtro\casp10, Xtro\casp3, Xtro\casp7, Xtro\pea15" "Mmus\Pea15a, Mmus\Casp9, Mmus\Cflar, Mmus\Casp6, Mmus\Casp14, Mmus\Casp7, Mmus\Casp4, Mmus\Casp2, Mmus\Casp3, Mmus\Casp8, Mmus\Casp12, Mmus\Casp1, Mmus\Pycard" "Hsap\CFLAR, Hsap\PYCARD, Hsap\CASP10, Hsap\CASP8, Hsap\CARD16, Hsap\CASP3, Hsap\PEA15, Hsap\CASP4, Hsap\CASP14, Hsap\CASP7, Hsap\CARD17, Hsap\CASP9, Hsap\CASP2, Hsap\CASP6, Hsap\CASP5, Hsap\CARD18, Hsap\CASP1, Hsap\CARD8" " pupal stage , embryonic stage -- adult stage " salivary gland

oogenesis stage | stage S10-12 nurse cell

"partially lethal - majority die,some die during pupal stage,visible,decreased cell death,viable,fertile,cell death defective,neuroanatomy defective,increased cell death,short lived,developmental rate defective,partially,tumorigenic,radiation resistant,drug conditional,male fertile,somatic clone,lethal - all die before end of pupal stage,some die during larval stage,wild-type,semi-sterile,some die during embryonic stage" "eye,eye disc,neuron,peptidergic neuron,ectopic,arista,male genitalia,adult abdomen,wing,retina,midline glial cell,spermatid cyst,somatic clone,wing disc,spermatogonial cyst,male germline cell,dendriteppk.PG,inter-ommatidial precursor cell,supernumerary,salivary gland | pupal stage" DRSC27804 K -0.320751614 0.434879514 -0.075726339 0.151745721 -0.711337791 1.745874793 FBgn0000504 dsx doublesex http://flybase.org/reports/FBgn0000504 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001275 protein binding ; GO:0005515 | inferred from physical interaction with ix transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement protein homodimerization activity ; GO:0042803 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement mRNA binding ; GO:0003729 | non-traceable author statement transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay" "male sex differentiation ; GO:0046661 | traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype male somatic sex determination ; GO:0019102 | non-traceable author statement central nervous system development ; GO:0007417 | traceable author statement female analia development ; GO:0045497 | non-traceable author statement sex differentiation ; GO:0007548 | traceable author statement sex determination ; GO:0007530 | traceable author statement courtship behavior ; GO:0007619 | non-traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | non-traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype genital disc development ; GO:0035215 | inferred from mutant phenotype sex differentiation ; GO:0007548 | non-traceable author statement genital disc morphogenesis ; GO:0007483 | traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement somatic sex determination ; GO:0018993 | non-traceable author statement female sex differentiation ; GO:0046660 | traceable author statement imaginal disc-derived female genitalia development ; GO:0007486 | inferred from genetic interaction with tra2 sex-specific pigmentation ; GO:0048071 | traceable author statement genital disc development ; GO:0035215 | traceable author statement female somatic sex determination ; GO:0019101 | non-traceable author statement imaginal disc-derived male genitalia development ; GO:0007485 | non-traceable author statement sex-specific pigmentation ; GO:0048071 | non-traceable author statement sex determination ; GO:0007530 | non-traceable author statement sex comb development ; GO:0045498 | traceable author statement imaginal disc-derived male genitalia development ; GO:0007485 | inferred from genetic interaction with tra2 regulation of imaginal disc growth ; GO:0045570 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement female somatic sex determination ; GO:0019101 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement genital disc sexually dimorphic development ; GO:0035263 | traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | traceable author statement imaginal disc-derived female genitalia development ; GO:0007486 | non-traceable author statement male analia development ; GO:0045496 | non-traceable author statement somatic sex determination ; GO:0018993 | traceable author statement male courtship behavior ; GO:0008049 | traceable author statement imaginal disc-derived female genitalia development ; GO:0007486 | inferred from mutant phenotype negative regulation of developmental pigmentation ; GO:0048086 | traceable author statement spermatogenesis ; GO:0007283 | non-traceable author statement" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026607 nucleus ; GO:0005634 | inferred by curator from GO:0001077 "doublesex, DSX, dsx, Dmdsx, Dsx, ix-62c, Hr, CG11094, dsxF, dsxM" "IPR001275:DM DNA-binding domain, IPR014932:Doublesex dimerisation, IPR026607:DMRT/protein doublesex/protein male abnormal 3" CG11094 11-Aug-17 DroID_v2017_08 "Drer\dmrt3a, Drer\dmrt2b, Drer\dmrta2, Drer\dmrt2a" - "Cele\dmd-3, Cele\dmd-9, Cele\dmd-10, Cele\dmd-7, Cele\mab-3, Cele\dmd-5, Cele\dmd-4, Cele\dmd-6, Cele\dmd-8" "Xtro\dmrta1, Xtro\kank1, Xtro\dmrt3, Xtro\dmrta2" "Mmus\Dmrtc1b, Mmus\Dmrt1, Mmus\Dmrtb1, Mmus\Dmrta1, Mmus\Dmrtc1c1, Mmus\Dmrt2, Mmus\Dmrtc1c2, Mmus\Dmrtc2, Mmus\Dmrt3, Mmus\Dmrta2, Mmus\Dmrtc1a" "Hsap\DMRTB1, Hsap\DMRTA1, Hsap\DMRTC2, Hsap\DMRTA2, Hsap\DMRT2, Hsap\DMRTC1B, Hsap\DMRT3, Hsap\DMRTC1, Hsap\DMRT1" "sex-determination defective,viable,fertile,male fertile,reduced,female fertile,dominant,female,chemical sensitive,neuroanatomy defective,courtship behavior defective,male,recessive,hyperactive,visible,heat sensitive,lethal,male sterile,partially,sterile,body color defective,female sterile,partially lethal - majority die,some die during pupal stage" "female accessory gland,spermathecum,prothoracic tarsal bristle,gonadal sheath proper primordium,female,female terminalia,female genitalia,female gonopod,prothoracic leg,female analia,anal plate,gonad,genitalia,germline cell,adult fruitless pMP-e (female) neuron,ectopic,genital disc,eye,leg,clasper,heat sensitive,penis,lateral plate,macrochaeta,embryonic/first instar larval cuticle,male analia,ovary,adult abdominal segment 6,male,male genitalia,sex comb,male accessory gland,flight muscle,male limited,testis,egg chamber,somatic clone,hub cell,epiproct,abdominal sternite 6,adult cuticle & abdominal segment 5 | female,adult cuticle & abdominal segment 6 | female,prothoracic leg taste bristle chemosensory neuron,adult abdominal segment 7,terminalia,abdominal tergite 7,serotonergic neuron,female genital disc,mesothoracic tergum" DRSC16934 I 1.921675821 0.1522242 -0.017176227 0.119665101 0.555135033 0.410370857 FBgn0053126 NLaz Neural Lazarillo http://flybase.org/reports/FBgn0053126 protein_coding_gene pigment binding ; GO:0031409 | inferred from electronic annotation with InterPro:IPR003057 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern carbohydrate homeostasis ; GO:0033500 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "CT33980, CG16933, CG33126, BcDNA:RE67583, NLaz, Nlaz, DNLaz" "IPR000566:Lipocalin/cytosolic fatty-acid binding domain, IPR012674:Calycin, IPR022271:Lipocalin, ApoD type, IPR003057:Invertebrate colouration protein" CG33126 11-Aug-17 DroID_v2017_08 "Drer\apoda.2, Drer\apoda.1, Drer\apodb" - Cele\lpr-4 - Mmus\Apod Hsap\APOD "stress response defective,short lived,starvation stress response defective,chemical sensitive,courtship behavior defective,long lived,viable" FBgn0000108 Appl beta amyloid protein precursor-like http://flybase.org/reports/FBgn0000108 FBgn0028498 protein_coding_gene transition metal ion binding ; GO:0046914 | inferred from electronic annotation with InterPro:IPR011178 heparin binding ; GO:0008201 | inferred from electronic annotation with InterPro:IPR015849 protein binding ; GO:0005515 | inferred from physical interaction with APP-BP1 protein binding ; GO:0005515 | inferred from physical interaction with Aplip1 protein binding ; GO:0005515 | inferred from physical interaction with Fas2 mushroom body development ; GO:0016319 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from direct assay response to axon injury ; GO:0048678 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype response to electrical stimulus ; GO:0051602 | inferred from mutant phenotype negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "APPL, APP, CG7727, Abeta, EG:65F1.5, appl, BcDNA:GH04413, Appl, APP-like, dAbeta" "IPR008154:Amyloidogenic glycoprotein, extracellular, IPR011178:Amyloidogenic glycoprotein, copper-binding, IPR015849:Amyloidogenic glycoprotein, heparin-binding, IPR019543:Beta-amyloid precursor protein C-terminal, IPR019744:Amyloidogenic glycoprotein, extracellular domain conserved site, IPR019745:Amyloidogenic glycoprotein, intracellular domain, conserved site, IPR024329:Amyloidogenic glycoprotein, E2 domain, IPR011990:Tetratricopeptide-like helical domain" CG7727 11-Aug-17 DroID_v2017_08 "Drer\appa, Drer\aplp2, Drer\aplp1, Drer\appb" - "Cele\apl-1, Cele\Y43F8B.3" "Xtro\app, Xtro\aplp1, Xtro\aplp2" "Mmus\Aplp2, Mmus\Aplp1, Mmus\App" "Hsap\APLP2, Hsap\APP, Hsap\APLP1" " pupal stage && adult stage , embryonic stage , larval stage , larval stage | third instar , embryonic stage -- adult stage , adult stage " " retina

, embryonic central nervous system

, optic lobe

, eye-antennal disc

, larval central nervous system

, central nervous system

, subesophageal ganglion

, peripheral nervous system

, head

" " embryonic stage , pupal stage && adult stage , larval stage , pupal stage&&adult stage , adult stage , pupal stage " " longitudinal connective

, medulla neuropil

, embryonic central nervous system

, ventral nerve cord commissure

, mushroom body

, neuromere &&of larval mesothoracic segment

, lamina

, photoreceptor cell

, ventral nerve cord

, peripheral nervous system

, Kenyon cell

, adult brain

, optic nerve

, larval optic stalk

, thoracico-abdominal ganglion

, lobula

, neuromere &&of larval metathoracic segment

, photoreceptor cell R1--8

, eye-antennal disc

, larval brain

, neuromere &&of larval abdominal segment 8

, lobe system of mushroom body

, neuromere &&of larval prothoracic segment

" "memory defective,neuroanatomy defective,viable,fertile,neurophysiology defective,visual behavior defective,visible,short lived,planar polarity defective,partially lethal - majority die,wild-type,increased cell death,phototaxis defective,progressive" "macrochaeta,bouton,ectopic,scutellar bristle,sternopleural bristle,NMJ bouton,anterior scutellar bristle,posterior scutellar bristle,embryonic/larval nervous system,adult brain,photoreceptor cell,photoreceptor cell R3,mechanosensory sensory organ,trichogen cell,eo neuron,ventral adult lateral neuron & dendritic treeP2.4.Pdf,wing,crossvein,wing vein,wing pouch,cell body rind of lamina,retina" FBgn0011274 Dif Dorsal-related immunity factor http://flybase.org/reports/FBgn0011274 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 protein binding ; GO:0005515 | inferred from physical interaction with MED17 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" immune response ; GO:0006955 | inferred from mutant phenotype positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay innate immune response ; GO:0045087 | non-traceable author statement I-kappaB kinase/NF-kappaB signaling ; GO:0007249 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 positive regulation of antifungal peptide biosynthetic process ; GO:0006967 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 response to fungus ; GO:0009620 | traceable author statement immune response ; GO:0006955 | traceable author statement NIK/NF-kappaB signaling ; GO:0038061 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype regulation of hemocyte proliferation ; GO:0035206 | inferred from direct assay salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from genetic interaction with Rel response to cytokine ; GO:0034097 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 plasmatocyte differentiation ; GO:0042387 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | traceable author statement peripheral nervous system neuron development ; GO:0048935 | inferred from mutant phenotype lamellocyte differentiation ; GO:0035171 | inferred from mutant phenotype innate immune response ; GO:0045087 | traceable author statement antifungal peptide production ; GO:0002781 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype defense response ; GO:0006952 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement I-kappaB/NF-kappaB complex ; GO:0033256 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 "Dif, dif, DIF, CG6794, 6794" "IPR000451:NF-kappa-B/Dorsal, IPR002909:IPT domain, IPR008967:p53-like transcription factor, DNA-binding, IPR011363:Dorsal-related immunity factor Dif, IPR011539:Rel homology domain (RHD), DNA-binding domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR030492:Rel homology domain, conserved site, IPR033926:NFkappaB IPT domain, IPR032397:Rel homology dimerisation domain" CG6794 11-Aug-17 DroID_v2017_08 "Drer\nfkb1, Drer\rela, Drer\nfkb2, Drer\relb, Drer\rel" - - "Xtro\relb, Xtro\rel, Xtro\rela" "Mmus\Nfkb1, Mmus\Rel, Mmus\Rela, Mmus\Relb, Mmus\Nfkb2" "Hsap\RELA, Hsap\RELB, Hsap\NFKB2, Hsap\REL, Hsap\NFKB1" " larval stage , pupal stage , adult stage " larval stage embryonic/larval fat body

"immune response defective,viable,fertile,visible,stress response defective,cold sensitive,dominant,recessive,short lived,conditional,lethal,partially" "macrochaeta,mesothoracic tergum,salivary gland,heat sensitive,ectopic,cold sensitive,dorsocentral bristle,embryonic/larval hemocyte,supernumerary,lamellocyte,plasmatocyte" FBgn0041621 Or82a Odorant receptor 82a http://flybase.org/reports/FBgn0041621 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay multicellular organism reproduction ; GO:0032504 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a extracellular space ; GO:0005615 | inferred from direct assay "CG31519, 82a, DOR61, Or82a, DmOR82A" "IPR004117:Olfactory receptor, insect" CG31519 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,viable" FBgn0002656 mat(2)cell-E maternal effect cellularisation defect E http://flybase.org/reports/FBgn0002656 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)cellQA13, mat(2)cell-E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0065426 l(2)SH1514 lethal (2) SH1514 http://flybase.org/reports/FBgn0065426 gene - - - "l(2)SH1514, l(2)SH2 1514" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053644 CG33644 - http://flybase.org/reports/FBgn0053644 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33644 IPR010512:Protein of unknown function DUF1091 CG33644 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035608 blanks blanks http://flybase.org/reports/FBgn0035608 protein_coding_gene siRNA binding ; GO:0035197 | inferred from direct assay sperm individualization ; GO:0007291 | inferred from mutant phenotype regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay "lump, CG10630, blanks" - CG10630 11-Aug-17 DroID_v2017_08 "Drer\stau2, Drer\stau1" - Cele\stau-1 - "Mmus\Stau1, Mmus\Stau2, Mmus\Adarb1" "Hsap\STAU1, Hsap\STAU2, Hsap\ADARB2, Hsap\ADARB1" "female fertile,male sterile,recessive,lethal,viable" "sperm individualization complex,individualization stage spermatid,spermatozoon,elongation stage spermatid" FBgn0083945 CG34109 - http://flybase.org/reports/FBgn0083945 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG12441, CG13129, CG13128, CG34109" "IPR005240:Protein of unknown function DUF389, IPR020846:Major facilitator superfamily domain" CG34109 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,viable" ganglion mother cell FBgn0046294 CG12699 - http://flybase.org/reports/FBgn0046294 protein_coding_gene - - - "BEST:GH14656, bs24f01.y1, NEST:bs24f01, anon-WO0140519.144, CG12699, GH14656" - CG12699 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032859 Arpc2 "Actin-related protein 2/3 complex, subunit 2" http://flybase.org/reports/FBgn0032859 protein_coding_gene actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000248611 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with HGNC:705 actin binding ; GO:0003779 | inferred from sequence or structural similarity structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000248611 Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from sequence or structural similarity with HGNC:705 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from biological aspect of ancestor with PANTHER:PTN000248611 contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay Arp2/3 protein complex ; GO:0005885 | inferred from biological aspect of ancestor with PANTHER:PTN000248611 apical cortex ; GO:0045179 | inferred from direct assay Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with HGNC:705 "ARPC2/p34, ARC-p34, Arpc2, p34, 38C.47, CG10954, ARC-P34, anon-WO0118547.154, ArcP34, Arc-p34, ARPC2, Arc-p34/Arpc2" "IPR007188:Actin-related protein 2/3 complex subunit 2, IPR034666:Arp2/3 complex subunit 2/4" CG10954 11-Aug-17 DroID_v2017_08 Drer\arpc2 Scer\ARC35 Cele\arx-4 Xtro\arpc2 Mmus\Arpc2 Hsap\ARPC2 "cell shape defective,visible,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,ommatidium,rhabdomere,chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC02113 I -1.282558552 -1.569719312 0.213656071 -0.452729051 -0.061080942 -0.060350133 FBgn0040348 CG3703 - http://flybase.org/reports/FBgn0040348 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 "BACR7A4.15, EG:BACR7A4.15, CG3703" IPR004012:RUN domain CG3703 11-Aug-17 DroID_v2017_08 "Drer\sgsm3, Drer\rabgap1l2, Drer\si:dkey-151m15.5, Drer\tbc1d5" - Cele\rund-1 "Xtro\rundc1, Xtro\sgsm3" "Mmus\Sgsm3, Mmus\Rundc1, Mmus\Tbc1d5" "Hsap\RUNDC1, Hsap\TBC1D5, Hsap\SGSM3" "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0011781 l(2)rG270 lethal (2) rG270 http://flybase.org/reports/FBgn0011781 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)rG270 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,lethal - all die before end of larval stage,recessive,some die during larval stage" "ovariole,germline clone,egg" FBgn0003267 ro rough http://flybase.org/reports/FBgn0003267 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 RNA polymerase II regulatory region DNA binding ; GO:0001012 | inferred from direct assay R8 cell fate specification ; GO:0045464 | traceable author statement R2/R5 cell differentiation ; GO:0048054 | inferred from mutant phenotype R8 cell fate commitment ; GO:0007460 | non-traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype R2/R5 cell fate commitment ; GO:0007463 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype negative regulation of R8 cell differentiation ; GO:0045680 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay "Ro, CG6348, ro, DROROUGH" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG6348 11-Aug-17 DroID_v2017_08 "Drer\hoxb8b, Drer\hoxb4a, Drer\hoxc3a, Drer\mnx1, Drer\gbx2, Drer\pdx1, Drer\hoxa3a, Drer\hoxb1b, Drer\hoxb1a, Drer\gsx2, Drer\gsx1, Drer\hoxc6a, Drer\mnx2a, Drer\hoxb2a, Drer\hoxa5a, Drer\hoxc8a, Drer\hoxc4a, Drer\meox2b, Drer\hoxa2b, Drer\hoxd3a, Drer\hoxc6b, Drer\hoxb5b, Drer\hoxb6a, Drer\hoxc1a, Drer\hoxd4a, Drer\hoxa4a, Drer\hoxb3a, Drer\hoxb6b, Drer\hoxb5a, Drer\meox1, Drer\hoxa9b, Drer\gbx1, Drer\hoxc5a, Drer\hoxb7a, Drer\hoxa1a, Drer\meox2a" "Scer\PHO2, Scer\YHP1, Scer\YOX1" "Cele\ceh-63, Cele\ceh-12, Cele\ceh-62, Cele\ceh-58" "Xtro\gbx2.2, Xtro\hoxb4, Xtro\hoxb5, Xtro\mnx1, Xtro\meox2, Xtro\hoxa1, Xtro\hoxb6, Xtro\gbx2.1, Xtro\hoxb2, Xtro\gsx2, Xtro\hoxa2, Xtro\hoxc5, Xtro\hoxa5, Xtro\hoxd3, Xtro\hoxd1, Xtro\pdx1, Xtro\hoxb7, Xtro\hoxb1, Xtro\hoxc3, Xtro\hoxb8, Xtro\hoxb3, Xtro\gsx1, Xtro\hoxc4, Xtro\hoxd8, Xtro\hoxa3, Xtro\hoxc8" "Mmus\Hoxb1, Mmus\Pdx1, Mmus\Obox2, Mmus\Gbx1, Mmus\Hoxd1, Mmus\Hoxd4, Mmus\Meox2, Mmus\Gbx2, Mmus\Hoxa1, Mmus\Hoxb3, Mmus\Obox7, Mmus\Hoxa7, Mmus\Hoxb5, Mmus\Hoxb6, Mmus\Hoxa2, Mmus\Gsx2, Mmus\Hoxd3, Mmus\Obox3, Mmus\Hoxc5, Mmus\Obox6, Mmus\Meox1, Mmus\Gsx1, Mmus\Hoxb2, Mmus\Hoxb4, Mmus\Hoxc8, Mmus\Mnx1, Mmus\Hoxa5, Mmus\Hoxa4, Mmus\Obox1, Mmus\Hoxa3, Mmus\Hoxd8, Mmus\Hoxa6, Mmus\Hoxb7, Mmus\Obox5, Mmus\Hoxb8, Mmus\Hoxc6, Mmus\Hoxc4" "Hsap\GSX1, Hsap\HOXC5, Hsap\HOXB1, Hsap\HOXA3, Hsap\HOXC4, Hsap\MEOX2, Hsap\HOXA1, Hsap\GSX2, Hsap\PDX1, Hsap\HOXB2, Hsap\HOXD4, Hsap\HOXD3, Hsap\HOXB5, Hsap\HOXB4, Hsap\GBX2, Hsap\HOXB3, Hsap\HOXB7, Hsap\GBX1, Hsap\HOXC8, Hsap\HOXB6, Hsap\HOXA7, Hsap\HOXB8, Hsap\MEOX1, Hsap\HOXA6, Hsap\HOXD1, Hsap\MNX1, Hsap\HOXA4, Hsap\HOXA2, Hsap\HOXC6, Hsap\HOXA5, Hsap\HOXD8" larval stage | third instar " photoreceptor cell R2..5

{ + vehs.sev } , mystery cell

" "planar polarity defective,recessive,visible,heat sensitive,lethal,wild-type,viable,dominant,lethal - all die before end of pupal stage,some die during pupal stage" "photoreceptor cell R3,ectopic,precursor,photoreceptor cell R4,photoreceptor cell R2,photoreceptor cell R5,ommatidium,eye photoreceptor cell,cone cell,eye,heat sensitive,photoreceptor cell R7,cell autonomous,somatic clone,photoreceptor cell R1,photoreceptor cell R6,retina,lens,primary pigment cell,macrochaeta,photoreceptor cell R8,supernumerary,morphogenetic furrow" DRSC17046 IE 0.045058179 -2.522851831 -1.553791393 -2.060778036 0.48289213 -0.650627194 FBgn0026371 SAK Sak kinase http://flybase.org/reports/FBgn0026371 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay" centriole replication ; GO:0007099 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay centrosome organization ; GO:0051297 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype regulation of centriole replication ; GO:0046599 | inferred from direct assay male meiosis ; GO:0007140 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of protein stability ; GO:0031647 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay centriole ; GO:0005814 | colocalizes_with inferred from direct assay "PLK4, Sak, SAK/PLK, CG7186, SAK, sak, Plk4, SAK/PLK4, plk4, DmSAK, Sak/Plk4" "IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR000959:POLO box domain, IPR033700:Serine/threonine-protein kinase Plk4, IPR033698:Plk4, second cryptic polo-box domain, IPR033699:Plk4, first cryptic polo-box domain, IPR033696:Plk4, C-terminal polo-box domain" CG7186 11-Aug-17 DroID_v2017_08 "Drer\si:rp71-1l17.1, Drer\si:dkey-58b18.10, Drer\plk2b, Drer\plk2a, Drer\pimr50, Drer\pimr63, Drer\pimr138, Drer\plk4, Drer\plk1, Drer\si:dkey-58b18.7, Drer\pimr80, Drer\si:dkey-1p9.2, Drer\plk3" "Scer\IPL1, Scer\CDC5" Cele\air-2 "Xtro\plk1, Xtro\plk3, Xtro\plk4, Xtro\plk2" "Mmus\Plk5, Mmus\Plk3, Mmus\Plk1, Mmus\Plk4, Mmus\Plk2" "Hsap\PLK3, Hsap\PLK2, Hsap\PLK1, Hsap\PLK4" "mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,developmental rate defective,male sterile,sterile,meiotic cell cycle defective,lethal,partially,some die during immature adult stage,uncoordinated,recessive,neuroanatomy defective" "embryo,centriolemat.‘±Tub67C.THsimVP16,centrosome,neuroblast,supernumerary,centrosome | supernumerary,centrosome & larval brain,spindle & larval brain,centriole & larval brain,centriole & primary spermatocyte,spindle & primary spermatocyte,centrosome & primary spermatocyte,astral microtubule & primary spermatocyte,spermatid axoneme,spermatid,spermatozoon,centriole,spermatocyte,spindle,primary spermatocyte,presumptive embryonic/larval peripheral nervous system,neuron,longitudinal connective,ventral nerve cord,embryonic/larval brain,centriole | ectopicmat.‘±Tub67C.THsimVP16,centriole | supernumerarymat.‘±Tub67C.THsimVP16" FBgn0031997 PGAP5 Post-GPI attachment to proteins 5 http://flybase.org/reports/FBgn0031997 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000330056 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000330056 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000330056 "PGAP5, CG8455" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR029052:Metallo-dependent phosphatase-like, IPR033308:PGAP5/Cdc1/Ted1" CG8455 11-Aug-17 DroID_v2017_08 Drer\mppe1 "Scer\TED1, Scer\CDC1" "Cele\ZK792.7, Cele\B0511.13" Xtro\mppe1 Mmus\Mppe1 Hsap\MPPE1 lethal FBgn0003360 sesB stress-sensitive B http://flybase.org/reports/FBgn0003360 "FBgn0001474, FBgn0001601, FBgn0001665, FBgn0005428, FBgn0005676, FBgn0027300, FBgn0028338, FBgn0040166, FBgn0064129, FBgn0066004" protein_coding_gene ATP:ADP antiporter activity ; GO:0005471 | inferred from sequence or structural similarity with UniProtKB:P12235 ATP:ADP antiporter activity ; GO:0005471 | inferred from mutant phenotype "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067, InterPro:IPR002113 action potential ; GO:0001508 | inferred from direct assay ATP transport ; GO:0015867 | inferred from sequence or structural similarity with UniProtKB:P12235 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from mutant phenotype synaptic vesicle transport ; GO:0048489 | inferred from direct assay mitochondrial calcium ion homeostasis ; GO:0051560 | inferred from mutant phenotype regulation of cytosolic calcium ion concentration ; GO:0051480 | inferred from mutant phenotype negative regulation of autophagy ; GO:0010507 | inferred from direct assay regulation of mitochondrial depolarization ; GO:0051900 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype positive regulation of ATP biosynthetic process ; GO:2001171 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype mitochondrial transport ; GO:0006839 | inferred from mutant phenotype regulation of mitochondrial membrane permeability ; GO:0046902 | inferred from biological aspect of ancestor with PANTHER:PTN000640049 oogenesis ; GO:0048477 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from direct assay ADP transport ; GO:0015866 | inferred from sequence or structural similarity with UniProtKB:P12235" integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:P12235 mitochondrial inner membrane ; GO:0005743 | inferred from direct assay "ses B, CG16944, orangi, ADP/ATP translocase, Hmr, A/A-T/sesB, ADT2, l(1)S12, S12, EM12, l(1)EM31, l(1)DC701, l(1)9Fa, l(1)9Ed, A/A-T, l(1)G0386, l(1)G0247, l(1)G0126, anon-WO02059370.55, sesB, jive, dANT, ANT, SesB, ANT1" "IPR018108:Mitochondrial substrate/solute carrier, IPR002067:Mitochondrial carrier protein, IPR002113:Adenine nucleotide translocator 1, IPR023395:Mitochondrial carrier domain" CG16944 11-Aug-17 DroID_v2017_08 "Drer\parvab, Drer\parvaa, Drer\si:dkey-251i10.1, Drer\slc25a4, Drer\slc25a5, Drer\slc25a6" "Scer\AAC1, Scer\PET9, Scer\AAC3" "Cele\F25B4.7, Cele\ant-1.3, Cele\ant-1.2, Cele\pat-6, Cele\ant-1.1, Cele\C47E12.2, Cele\ant-1.4, Cele\R07E3.4" "Xtro\slc25a4, Xtro\parvb, Xtro\slc25a5" "Mmus\Slc25a4, Mmus\Parvb, Mmus\Slc25a31, Mmus\Slc25a5, Mmus\Parva" "Hsap\SLC25A5, Hsap\PARVB, Hsap\SLC25A6, Hsap\SLC25A31, Hsap\SLC25A4, Hsap\PARVA" " embryonic stage | mid-late , adult stage " "paralytic,conditional,neuroanatomy defective,neurophysiology defective,lethal,recessive,viable,fertile,male,oxidative stress response defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,wild-type,partially lethal - majority die,heat sensitive,flightless,female,reduced,cold sensitive,female sterile,short lived,locomotor behavior defective,bang sensitive,hypoactive,developmental rate defective,auditory perception defective,courtship behavior defective,male limited,majority die during embryonic stage,maternal effect,lethal - all die before end of larval stage,some die during larval stage,visible,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,behavior defective,lethal - all die before end of P-stage,some die during pharate adult stage" "NMJ bouton,supernumerary,ovariole,germline clone,eye,somatic clone,embryonic/larval Malpighian tubule,mitochondrion | larval stagec42,mitochondrion | larval stagec710,mitochondrion | larval stageUro.PT,mitochondrion | larval stagehs.PB,thoracico-abdominal ganglion,flight muscle,neuromuscular junction,Malpighian tubule,mitochondrion,egg chamber,maternal effect,trichogen cell,mesothoracic tergum" DRSC20371 E -0.27849747 -0.003666531 -2.499123017 0.120338607 -1.147290991 -0.47908395 FBgn0043001 Chrac-16 Chromatin accessibility complex 16kD protein http://flybase.org/reports/FBgn0043001 protein_coding_gene nucleosome-dependent ATPase activity ; GO:0070615 | contributes_to inferred by curator from GO:0008623 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Chrac-14 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype nucleosome mobilization ; GO:0042766 | inferred from direct assay CHRAC ; GO:0008623 | inferred from direct assay "CHRAC16, Chrac-16, CHRAC, CHRAC-16, joey, CG15736, BcDNA:RE59557, 15736, Chrac16, 20K protein" "IPR003958:Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072:Histone-fold" CG15736 11-Aug-17 DroID_v2017_08 "Drer\pole4, Drer\chrac1, Drer\nfyc" "Scer\DPB3, Scer\HAP5, Scer\DLS1" "Cele\nfyc-1, Cele\Y53F4B.3" "Xtro\chrac1, Xtro\nfyc" "Mmus\Nfyc, Mmus\Pole4, Mmus\Chrac1" "Hsap\CHRAC1, Hsap\POLE4, Hsap\NFYC" viable DRSC20343 E 1.03258003 0.781101856 6.631703228 -0.2884066 -0.31536503 0.5793855 FBgn0013997 Nrx-IV Neurexin IV http://flybase.org/reports/FBgn0013997 FBgn0002261 protein_coding_gene - "regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype cell-cell junction organization ; GO:0045216 | traceable author statement cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype synaptic vesicle targeting ; GO:0016080 | non-traceable author statement axon ensheathment ; GO:0008366 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement protein localization ; GO:0008104 | traceable author statement presynaptic membrane assembly ; GO:0097105 | inferred from mutant phenotype heart process ; GO:0003015 | inferred from mutant phenotype dorsal closure ; GO:0007391 | non-traceable author statement terminal button organization ; GO:0072553 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype nerve maturation ; GO:0021682 | inferred from mutant phenotype synaptic vesicle docking ; GO:0016081 | non-traceable author statement" presynaptic active zone ; GO:0048786 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | non-traceable author statement pleated septate junction ; GO:0005919 | inferred from direct assay septate junction ; GO:0005918 | non-traceable author statement septate junction ; GO:0005918 | traceable author statement synapse ; GO:0045202 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "Nrx, NRX, nrx IV, nrx, NrxIV, Nrx IV, CG6827, nrxIV, CT21123, NRX IV, Dnrx, Nx IV, rsg23, l(3)rsg23, l(3)68Ff, Nrx-IV, nrx-IV, CG682" "IPR000421:Coagulation factor 5/8 C-terminal domain, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR003585:Neurexin/syndecan/glycophorin C, IPR008979:Galactose-binding domain-like, IPR013320:Concanavalin A-like lectin/glucanase domain" CG6827 11-Aug-17 DroID_v2017_08 "Drer\cntnap3, Drer\cntnap5b, Drer\cntnap1, Drer\cntnap2b, Drer\cntnap2a, Drer\cntnap5a, Drer\cntnap5l" - Cele\nlr-1 "Xtro\cntnap1, Xtro\cntnap2, Xtro\cntnap4" "Mmus\Cntnap4, Mmus\Cntnap5a, Mmus\Cntnap1, Mmus\Cntnap5c, Mmus\Cntnap5b, Mmus\Cntnap2, Mmus\Cntnap3" "Hsap\LOC100289279, Hsap\CNTNAP1, Hsap\CNTNAP3, Hsap\CNTNAP2, Hsap\CNTNAP3B, Hsap\CNTNAP5, Hsap\CNTNAP4" " embryonic stage | stage >=11 , embryonic stage -- adult stage " " chordotonal organ

, central nervous system | restricted

, glial cell

, embryonic/larval proventriculus

, embryonic/larval pharynx

, tracheal system

, peripheral nervous system | restricted

, embryonic/larval esophagus

, scolopidium

, epidermis

, embryonic/larval salivary gland

, embryonic/larval hindgut

" "viable,learning defective,neuroanatomy defective,lethal,recessive,decreased cell number,somatic clone,visible,paralytic,neurophysiology defective" "embryonic/larval salivary gland,germline cell,male,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,embryonic/larval brain,somatic clone,eye,wing,wing vein,leg,axolemma & nerve,epithelium,embryonic/first instar larval cuticle,dorsal,embryonic epidermis,neuromuscular junction,pleated septate junction,embryonic ganglionic branch & embryonic tracheole,dorsal trunk primordium,scolopidium,central nervous system,presumptive embryonic/larval tracheal system,abdominal lateral pentascolopidial chordotonal organ lch5,scolopidium & abdominal lateral pentascolopidial chordotonal organ lch5,septate junction & peripheral glial cell,septate junction" FBgn0034627 eEFSec "eukaryotic translation elongation factor, selenocysteine-specific" http://flybase.org/reports/FBgn0034627 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with EMBL:AF283518 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with EMBL:AF283518 GTPase activating protein binding ; GO:0032794 | inferred from physical interaction with GAPsec" translational readthrough ; GO:0006451 | inferred from mutant phenotype translational elongation ; GO:0006414 | inferred from sequence or structural similarity with EMBL:AF283518 selenocysteine incorporation ; GO:0001514 | inferred from mutant phenotype "cytoplasm ; GO:0005737 | inferred by curator from GO:0001514,GO:0006451" "CG9841, Efsec, EFSec, Eftu, SelB/eEFsec, EfSec, EFsec, eEFsec, deEFsec, dEFsec, eEFSec" "IPR000795:Transcription factor, GTP-binding domain, IPR005225:Small GTP-binding protein domain, IPR009000:Translation protein, beta-barrel domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9841 11-Aug-17 DroID_v2017_08 Drer\eefsec Scer\TUF1 "Cele\efsc-1, Cele\tufm-2" Xtro\eefsec Mmus\Eefsec Hsap\EEFSEC "fertile,viable,short lived,chemical conditional" DRSC04571 I 1.546270683 0.216073631 0.930844801 -0.457775557 -1.479550061 -0.85808628 FBgn0004620 GluRIIA Glutamate receptor IIA http://flybase.org/reports/FBgn0004620 - protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 ionotropic glutamate receptor activity ; GO:0004970 | inferred from mutant phenotype kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity glutamate receptor activity ; GO:0008066 | inferred from direct assay glutamate-gated calcium ion channel activity ; GO:0022849 | inferred from direct assay "synaptic transmission, glutamatergic ; GO:0035249 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from direct assay regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from direct assay neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from genetic interaction with Exn, cac chemical synaptic transmission ; GO:0007268 | inferred from direct assay regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype synapse maturation ; GO:0060074 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype regulation of synaptic activity ; GO:0060025 | inferred from direct assay" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with RGDID:2735 inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay ionotropic glutamate receptor complex ; GO:0008328 | inferred from mutant phenotype postsynaptic membrane ; GO:0045211 | colocalizes_with inferred from direct assay "GluRIIa, DGluR-IIA, D-GluRIIA, dglurIIA, GluR2a, dglur-IIA, dGluRIIA, GluRII-A, DGluRIIA, GluRII, GlurIIA, DgluRII, glurIIA, GluR, DGluR2a, DGluR-II, dGluRII, Glu-RII, CG6992, Glu-RIIA, GluRIIA, DmelGluRIIA, DGluRIIa, GluR-IIA, gluriia, GluR[[IIa]], GluR2, gluRIIA, gluIIA" "IPR001320:Ionotropic glutamate receptor, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001508:Ionotropic glutamate receptor, metazoa" CG6992 11-Aug-17 DroID_v2017_08 "Drer\grik5, Drer\grik1b, Drer\LOC100331381, Drer\si:dkey-183j2.10, Drer\si:ch211-251b21.1, Drer\grik4, Drer\LOC100334689, Drer\grik1a" - "Cele\glr-6, Cele\glr-5, Cele\glr-8, Cele\glr-3, Cele\glr-4" "Xtro\grik5, Xtro\grik1, Xtro\grik4" "Mmus\Grik4, Mmus\Grik3, Mmus\Grin2a, Mmus\Grik2, Mmus\Grik1, Mmus\Grik5" "Hsap\GRIK4, Hsap\GRIK1, Hsap\GRIK2, Hsap\GRIK3, Hsap\GRIN2A, Hsap\GRIK5" embryonic stage | stage 17 larval neuromuscular junction

"wild-type,neurophysiology defective,viable,neuroanatomy defective,recessive,locomotor behavior defective,heat sensitive,lethal" "NMJ bouton,synapse, with Df(2L)SP22, Df(2L)cl-h4, ,synapse,synaptic vesicle,bouton,embryonic/larval neuromuscular junction,neuromuscular junction,t-bar,heat sensitive,type I bouton,synapse, with Df(2L)SP22, Df(2L)cl-h4, RapGAP1-OK6,presynaptic active zone membrane, with Df(2L)SP22, Df(2L)cl-h4, RapGAP1-OK6,postsynaptic membrane, with Df(2L)SP22, Df(2L)cl-h4, RapGAP1-OK6,synaptic vesiclehow-24B,neuromuscular junction | larval stagehow-24B,synapseMhc.PW,neuromuscular junction | larval stageMhc.PW" FBgn0038320 Sra-1 specifically Rac1-associated protein 1 http://flybase.org/reports/FBgn0038320 protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:B1Q236,UniProtKB:P55162,UniProtKB:Q8MLQ0,UniProtKB:Q9VKM2,UniProtKB:Q9Y0S9 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40792 inferred from physical interaction with UniProtKB:Q9NFU0" chaeta development ; GO:0022416 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype apical part of cell ; GO:0045177 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:13759 inferred from sequence or structural similarity with HGNC:13760 synapse ; GO:0045202 | inferred from sequence or structural similarity with HGNC:13759 inferred from sequence or structural similarity with HGNC:13760 SCAR complex ; GO:0031209 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Sra-1, CYFIP, sra1, Sra, CYFIP1/2, PIR121/Sra-1, Sra1, DSra-1, CG4931, PIR121, Sra1/PIR121, dSra, sra-1, Sra-1/CYFIP, cyfip" "IPR008081:Cytoplasmic FMR1-interacting, IPR009828:Protein of unknown function DUF1394" CG4931 11-Aug-17 DroID_v2017_08 "Drer\cyfip2, Drer\cyfip1" - Cele\gex-2 Xtro\cyfip2 "Mmus\Cyfip1, Mmus\Cyfip2" "Hsap\CYFIP2, Hsap\CYFIP1" "visible,viable,fertile,partially lethal - majority live,lethal - all die before end of P-stage,some die during pharate adult stage,cell shape defective,lethal,recessive,neuroanatomy defective,dominant,germline clone,somatic clone" "eye | adult stage,photoreceptor | adult stage,eye,cone cell,ommatidium,retina,lens,interommatidial bristle,rhabdomere | pharate adult stage,photoreceptor,rhabdomere | pupal stage,microchaeta,trichogen cell & actin filament & pupa.PC,adult head & macrochaeta.PC,intersegmental nerve,axon,neuromuscular junction & synapse,longitudinal connective,commissure,synapse,bouton,presumptive embryonic/larval central nervous system,germline clone,embryonic/larval neuromuscular junction,somatic clone,rhabdomere | adult stage | somatic clone,S2 cell-line & filopodium | ectopic,S2 cell-line & actin filament | ectopic,photoreceptor cell & growth cone & larval brainey.PH,photoreceptor cell | wandering third instar larval stage,larval neuromuscular junction & bouton" FBgn0002683 mat(3)1 maternal lethal 1 http://flybase.org/reports/FBgn0002683 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mat(3)1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,non-rescuable maternal effect" "cycle 14 embryo,maternal effect,pole cell,non-rescuable maternal effect,blastoderm embryo,nucleus | blastoderm stage | non-rescuable maternal effect,syncytial blastoderm embryo" FBgn0014391 sun stunted http://flybase.org/reports/FBgn0014391 "FBgn0014975, FBgn0040875, FBgn0047007, FBgn0047155" protein_coding_gene "ATPase activity ; GO:0016887 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000278562 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O97148 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000006192 G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with mth" lateral inhibition ; GO:0046331 | inferred from mutant phenotype ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000006192 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P56381 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype positive regulation of G-protein coupled receptor protein signaling pathway ; GO:0045745 | inferred from direct assay response to oxidative stress ; GO:0006979 | inferred from mutant phenotype "mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P56381 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000278562 extracellular space ; GO:0005615 | inferred from direct assay" "CG9032, l(1)XV, l(1)13Fe, BcDNA:RH48911, BcDNA:RE19513, sun, Sun, ATP5E, ATPE, ATPsynepsilon" "IPR006721:ATP synthase, F1 complex, epsilon subunit, mitochondrial" CG9032 11-Aug-17 DroID_v2017_08 Drer\atp5e Scer\ATP15 "Cele\ZC262.5, Cele\R05D3.6, Cele\hpo-18" - Mmus\Atp5e Hsap\ATP5E "female sterile,lethal,partially,viable,recessive,wild-type,visible,long lived,stress response defective,lethal - all die before end of embryonic stage,germline clone,maternal effect,some die during embryonic stage,dominant,chemical resistant,partially lethal - majority die,some die during pupal stage" "wing,nucleus | embryonic cycle 14 | germline clone | maternal effect,centrosome | germline clone | maternal effect,spindle | germline clone | maternal effect,nucleus | embryonic cycle 12 | germline clone | maternal effect,nucleus | embryonic cycle 13 | germline clone | maternal effect,nucleus | embryonic stage 5 | germline clone | maternal effect,egg,germline clone,maternal effect,chaeta,trichogen cell" FBgn0260341 GSd427 - http://flybase.org/reports/FBgn0260341 gene - - - GSd427 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,neuroanatomy defective,viable" "ventral nerve cord,intersegmental nerve,eye photoreceptor cell" FBgn0000063 Mps1 Monopolar spindle 1 http://flybase.org/reports/FBgn0000063 FBgn0038534 protein_coding_gene "protein serine/threonine/tyrosine kinase activity ; GO:0004712 | inferred from electronic annotation with InterPro:IPR027084 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271 female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype meiotic spindle checkpoint ; GO:0044779 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype achiasmate meiosis I ; GO:0000705 | inferred from mutant phenotype meiotic metaphase I plate congression ; GO:0043060 | inferred from mutant phenotype male germ-line stem cell asymmetric division ; GO:0048133 | inferred from genetic interaction with Mtor distributive segregation ; GO:0032837 | inferred from mutant phenotype inferred from genetic interaction with Axs mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype meiotic spindle assembly checkpoint ; GO:0033316 | inferred from mutant phenotype negative regulation of sister chromatid segregation ; GO:0033046 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement female meiotic division ; GO:0007143 | inferred from mutant phenotype" centrosome ; GO:0005813 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay condensed nuclear chromosome outer kinetochore ; GO:0000942 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay "Mps1, mps1, ald, CG7643, TKK, dMps1, Ald/Mps1, Msp1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR027084:Protein kinase Mps1 family" CG7643 11-Aug-17 DroID_v2017_08 Drer\ttk Scer\MPS1 - "Xtro\ttk, Xtro\map2k6" Mmus\Ttk "Hsap\TTK, Hsap\TTBK2" "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,mitotic cell cycle defective,conditional,lethal - all die before end of embryonic stage,some die during embryonic stage,meiotic cell cycle defective,female,viable,fertile,germline clone,partially lethal - majority die" "eye,ommatidium,wing,mitotic cell cycle | germline clone,anaphase & condensed nuclear chromosome | germ-line clone,nucleus | germline clone,polar body nucleus,germline clone,kinetochore | embryonic stage 5mat.‘±Tub67C.THsimVP16,meiosis & nuclear chromosomeED5780),meiosis & nuclear chromosome,oocyte,spindle microtubule & oocyte,spindle pole & oocyte,chromosome & oocyte" FBgn0001515 l(1)10Fi lethal (1) 10Fi http://flybase.org/reports/FBgn0001515 - gene - - - l(1)10Fi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,polyphasic,recessive,cell lethal,germline clone" FBgn0001386 l(1)2Br lethal (1) 2Br http://flybase.org/reports/FBgn0001386 - gene - - - l(1)2Br - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005624 Psc Posterior sex combs http://flybase.org/reports/FBgn0005624 "FBgn0002071, FBgn0003153, FBgn0003644" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 DNA binding ; GO:0003677 | inferred from direct assay core promoter binding ; GO:0001047 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model chromatin silencing ; GO:0006342 | inferred from direct assay ventral cord development ; GO:0007419 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from direct assay intercalary heterochromatin ; GO:0005725 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay PRC1 complex ; GO:0035102 | traceable author statement PcG protein complex ; GO:0031519 | inferred from direct assay PRC1 complex ; GO:0035102 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay "Psc, PSC, psc, CG3886, dPSC, Psc1, l(2)49Ea, vr14, Su(z)2-C, l(2)Psc, 49Ea, l(2)vr14, D-Bmi" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR018957:Zinc finger, C3HC4 RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR032443:RAWUL domain" CG3886 11-Aug-17 DroID_v2017_08 "Drer\rnf2, Drer\pcgf5b, Drer\bmi1a, Drer\pcgf6, Drer\pcgf5a, Drer\bmi1b" Scer\RAD18 "Cele\mig-32, Cele\spat-3" "Xtro\pcgf3, Xtro\pcgf2, Xtro\pcgf6, Xtro\bmi1" "Mmus\Pcgf1, Mmus\Pcgf2, Mmus\Pcgf3, Mmus\Bmi1, Mmus\Pcgf5, Mmus\Pcgf6, Mmus\Rnf2, Mmus\Ring1" "Hsap\COMMD3-BMI1, Hsap\BMI1, Hsap\PCGF3, Hsap\RING1, Hsap\PCGF2, Hsap\PCGF1, Hsap\PCGF5, Hsap\RNF2, Hsap\PCGF6" " larval stage | third instar , pupal stage | 24 hr , embryonic stage -- adult stage , oogenesis stage && adult stage | female " " larval central nervous system

, adult brain

, ovary

, imaginal disc

" " embryonic stage , larval stage | third instar , larval stage | first instar " " embryonic/larval salivary gland

, imaginal disc

, larval brain

, ventral nerve cord

, central nervous system

, pole cell

" "viable,eye color defective,dominant,visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,non-suppressor of variegation,partially lethal - majority die,homeotic,mitotic cell cycle defective,suppressor of variegation,non-enhancer of variegation,somatic clone" "wing,posterior compartment,alula,pigment cell,head & macrochaeta,scutum & macrochaeta,scutellum & macrochaeta,costal vein & macrochaeta,leg & macrochaeta,abdomen & macrochaeta,dorsal triple row & macrochaeta,ventral triple row & macrochaeta,dorsal double row & macrochaeta,ventral double row & macrochaeta,embryonic epidermis,denticle belt,macrochaeta,embryonic head,embryonic thorax,embryonic abdomen,mesothoracic leg,metathoracic leg,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,anaphase | embryonic stage,telophase | embryonic stage,sex comb,supernumerary,somatic clone" FBgn0002518 l(3)Sp19 lethal (3) Sp19 http://flybase.org/reports/FBgn0002518 - gene - - - l(3)Sp19 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0028331 l(1)G0289 lethal (1) G0289 http://flybase.org/reports/FBgn0028331 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002165 "CG2221, l(1)G0289, lethal (1) G0289, Mgn1457" "IPR002165:Plexin repeat, IPR031152:Plexin domain-containing protein" CG2221 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-106h4.6, Drer\plxdc1, Drer\plxdc2" - Cele\pxd-1 Xtro\plxdc2 "Mmus\Plxdc2, Mmus\Plxdc1" "Hsap\PLXDC2, Hsap\PLXDC1" "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,body color defective,long lived,male limited" mesothoracic tergum FBgn0032728 Tango6 Transport and Golgi organization 6 http://flybase.org/reports/FBgn0032728 protein_coding_gene - Golgi organization ; GO:0007030 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs protein secretion ; GO:0009306 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG18398, TANGO6, Tango6" "IPR016024:Armadillo-type fold, IPR019414:RNA polymerase II assembly factor Rtp1, C-terminal domain 2, IPR011989:Armadillo-like helical, IPR019451:RNA polymerase II assembly factor Rtp1, C-terminal" CG18398 11-Aug-17 DroID_v2017_08 Drer\tango6 "Scer\RTP1, Scer\BTN2" Cele\ekl-6 Xtro\tango6 "Mmus\S100a4, Mmus\Tango6" Hsap\TANGO6 "lethal,partially lethal - majority die,visible" "embryonic/larval brain,mesothoracic tergum" DRSC02671 I -1.076371589 2.166374572 -0.667438859 -0.096834721 -0.781265197 0.590880216 FBgn0004179 Csp Cysteine string protein http://flybase.org/reports/FBgn0004179 "FBgn0010827, FBgn0066009" protein_coding_gene - negative regulation of response to wounding ; GO:1903035 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity synaptic vesicle uncoating ; GO:0016191 | traceable author statement neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with FLYBASE:GluRIinferred by curator; FB:FBgn0046113 protein folding ; GO:0006457 | non-traceable author statement brain morphogenesis ; GO:0048854 | inferred from mutant phenotype regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from genetic interaction with FLYBASE:GluRIinferred by curator; FB:FBgn0046113 exocytosis ; GO:0006887 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | traceable author statement locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | traceable author statement startle response ; GO:0001964 | inferred from mutant phenotype type Ib terminal bouton ; GO:0061176 | inferred from direct assay synaptic vesicle ; GO:0008021 | traceable author statement terminal bouton ; GO:0043195 | inferred from direct assay type Is terminal bouton ; GO:0061177 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay synaptic vesicle ; GO:0008021 | "CSP, csp, Cys, ab49, D.M.CSP, CG6395, l(3)03988, csp32, csp29, Dcsp, CSP32, D-CSP, MAB ab49, DCSP-1, anon-WO02059370.50, Csp, DSP/DNAJC5, DNAJC5" "IPR018253:DnaJ domain, conserved site, IPR001623:DnaJ domain" CG6395 11-Aug-17 DroID_v2017_08 "Drer\dnajc5b, Drer\dnajc5aa, Drer\dnajc5ga, Drer\dnajc5gb, Drer\dnajc5ab" "Scer\CAJ1, Scer\SCJ1, Scer\XDJ1, Scer\SIS1, Scer\ERJ5, Scer\JEM1, Scer\JJJ2, Scer\CWC23" "Cele\dnj-26, Cele\dnj-14, Cele\dnj-24, Cele\dnj-16" Xtro\dnajc5g "Mmus\Dnajc5b, Mmus\Dnajc5g, Mmus\Dnajc5" "Hsap\DNAJC5G, Hsap\DNAJC5B, Hsap\DNAJC5" adult stage " adult head

, adult brain

, retina

" " adult stage , larval stage " " photoreceptor cell

, neuropil

, lamina neuropil

, neuromuscular junction &&of adult thorax

, lobula plate neuropil

, medulla neuropil

, neuromuscular junction

, bouton

, neuron

" "lethal,partially lethal - majority die,recessive,paralytic,heat sensitive,neurophysiology defective,courtship behavior defective,male,viable,reduced,conditional,partially,uncoordinated,short lived,wild-type,optomotor response defective,visible,hypoactive,behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" "axon | larval stage,neuromuscular junction,embryonic/larval neuromuscular junction,germline cell,male,neuromuscular junction | larval stage,wing,eye,ommatidium,interommatidial bristle" FBgn0086067 snoRNA:Me28S-A771 - http://flybase.org/reports/FBgn0086067 snoRNA_gene - - - "snoRNA:Me28S-A771, Me28S-Am771, Me28S-A771, CR34696" - CR34696 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002998 oml ommatidialess http://flybase.org/reports/FBgn0002998 - gene - - - oml - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "ocellus,antenna,head,eye,ommatidium" FBgn0040318 HGTX HGTX http://flybase.org/reports/FBgn0040318 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with gro" negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay central nervous system development ; GO:0007417 | inferred from genetic interaction with mid positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay negative regulation of gene expression ; GO:0010629 | inferred from genetic interaction with mid neuron differentiation ; GO:0030182 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Nkx6, Nk6, CG4745, dNkx6, CG13475, HGTX, nkx6" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG13475 11-Aug-17 DroID_v2017_08 "Drer\nkx6.1, Drer\tlx3b, Drer\tlx2, Drer\nkx6.2, Drer\tlx1, Drer\LOC100008066, Drer\nkx6.3" - "Cele\alr-1, Cele\cog-1, Cele\nob-1, Cele\egl-5" "Xtro\nkx6-2, Xtro\tlx1, Xtro\nkx6-3, Xtro\tlx3, Xtro\tlx2, Xtro\nkx6-1" "Mmus\Tlx2, Mmus\Nkx6-2, Mmus\Tlx3, Mmus\Nkx6-1, Mmus\Nkx6-3, Mmus\Tlx1" "Hsap\TLX1, Hsap\NKX6-2, Hsap\NKX6-1, Hsap\NKX6-3, Hsap\TLX3, Hsap\TLX2" "neuroanatomy defective,viable" "intersegmental nerve,RP2 motor neuron,ectopic,U neuron,EL neuron,EW neuron,motor neuron,intersegmental nerve branch ISNb of A1-7,fascicle,interneuron & axon & longitudinal connective,RP neuron & axon & embryo,intersegmental nerve | embryonic stage" FBgn0034012 Hr51 Hormone receptor 51 http://flybase.org/reports/FBgn0034012 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628 steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 heme binding ; GO:0020037 | inferred from direct assay" steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 locomotor rhythm ; GO:0045475 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype axon regeneration ; GO:0031103 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype positive regulation of axon extension involved in axon guidance ; GO:0048842 | inferred from mutant phenotype imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:1100526 axon guidance ; GO:0007411 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "NR2E3, PNR, DHR51, CG16801/NR2E3, Hr51, CG16801, fdx, unf, Nr2e3, UNF, HR51" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type" CG16801 11-Aug-17 DroID_v2017_08 "Drer\nr0b1, Drer\nr2f6b, Drer\nr2f1b, Drer\nr2e3, Drer\thrab, Drer\nr2c1, Drer\pgr, Drer\raraa, Drer\esrra, Drer\nr1h5, Drer\nr2f1a, Drer\nr2c2, Drer\esr2b, Drer\nr1h4, Drer\rargb, Drer\ar, Drer\ppardb, Drer\rarab, Drer\nr6a1b, Drer\rxrba, Drer\nr2f5, Drer\nr2e1, Drer\esrrd, Drer\nr3c1, Drer\pparab, Drer\nr0b2b, Drer\nr1i2, Drer\nr2f2, Drer\nr0b2a, Drer\rxrab, Drer\pparaa, Drer\rxraa, Drer\rxrga, Drer\vdra, Drer\rxrbb, Drer\esr2a, Drer\pparda, Drer\nr5a1a, Drer\nr2f6a, Drer\vdrb, Drer\pparg, Drer\esrrga, Drer\esr1" - "Cele\nhr-89, Cele\nhr-264, Cele\nhr-187, Cele\nhr-174, Cele\nhr-217, Cele\nhr-67, Cele\nhr-81, Cele\nhr-111, Cele\nhr-82, Cele\nhr-165, Cele\nhr-113, Cele\nhr-259, Cele\nhr-169, Cele\nhr-164, Cele\fax-1, Cele\nhr-265, Cele\nhr-267, Cele\nhr-234, Cele\nhr-72, Cele\nhr-74, Cele\nhr-20, Cele\nhr-244, Cele\nhr-257, Cele\nhr-92, Cele\nhr-155, Cele\nhr-235, Cele\dpr-1, Cele\nhr-239, Cele\nhr-73, Cele\nhr-251" "Xtro\rarb, Xtro\nr6a1, Xtro\rarg, Xtro\pgr, Xtro\rxrg, Xtro\ar, Xtro\nr2f6, Xtro\nr3c2, Xtro\esrra, Xtro\nr1h2, Xtro\ppara, Xtro\esr1, Xtro\nr2f2, Xtro\nr0b2, Xtro\rara, Xtro\esr2, Xtro\nr2f1, Xtro\thrb, Xtro\esrrb, Xtro\esrrgr, Xtro\nr2c1, Xtro\ppard, Xtro\nr1h5, Xtro\nr2e1, Xtro\nr2c2, Xtro\esrrg, Xtro\rxra, Xtro\nr0b1, Xtro\nr3c1, Xtro\nr2f5, Xtro\pparg, Xtro\rxrb, Xtro\nr1i2, Xtro\vdr, Xtro\nr2e3" "Mmus\Nr1h3, Mmus\Nr2f1, Mmus\Ppard, Mmus\Rxrb, Mmus\Nr1h5, Mmus\Nr1h2, Mmus\Thra, Mmus\Vdr, Mmus\Nr3c1, Mmus\Rxrg, Mmus\Esr2, Mmus\Esrrg, Mmus\Nr2f2, Mmus\Nr1h4, Mmus\Nr2e1, Mmus\Rarg, Mmus\Nr6a1, Mmus\Esrrb, Mmus\Pparg, Mmus\Nr0b1, Mmus\Rxra, Mmus\Nr0b2, Mmus\Nr1i2, Mmus\Thrb, Mmus\Esrra, Mmus\Rarb, Mmus\Pgr, Mmus\Esr1, Mmus\Nr1i3, Mmus\Nr3c2, Mmus\Nr2f6, Mmus\Ppara, Mmus\Ar, Mmus\Nr2e3, Mmus\Rara, Mmus\Nr2c2, Mmus\Nr2c1" "Hsap\NR2E3, Hsap\ESRRG, Hsap\THRA, Hsap\NR0B1, Hsap\RXRA, Hsap\PPARA, Hsap\ESRRA, Hsap\NR1I3, Hsap\ESR2, Hsap\RARA, Hsap\PPARD, Hsap\ESRRB, Hsap\NR2F6, Hsap\NR1H3, Hsap\AR, Hsap\PPARG, Hsap\RARB, Hsap\RXRB, Hsap\RARG, Hsap\ESR1, Hsap\RXRG, Hsap\THRB, Hsap\NR2E1, Hsap\NR0B2, Hsap\NR1I2, Hsap\NR6A1, Hsap\VDR, Hsap\NR2C1, Hsap\NR2C2, Hsap\NR1H2, Hsap\NR3C1, Hsap\NR2F2, Hsap\NR2F1, Hsap\NR1H4, Hsap\PGR, Hsap\NR3C2" "lethal,neuroanatomy defective,somatic clone,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,visible,male sterile,female sterile,recessive" "gamma Kenyon cell,somatic clone,axonTab2-201Y,dendriteTab2-201Y,mushroom body | adult stage,mushroom body vertical lobe | third instar larval stage,mushroom body | pupal stage,mushroom body gamma-lobe,adult mushroom body,mushroom body gamma-lobe | adult stage,mushroom body alpha-lobe | pupal stage,mushroom body alpha'-lobe | pupal stage,mushroom body beta-lobe | pupal stage,mushroom body beta'-lobe | pupal stage,mushroom body,heat sensitive,lobe system of adult mushroom body,wing,alpha/beta Kenyon cell,ganglion mother cell" DRSC06627 I 2.097364643 -0.199922496 -0.003925285 -0.870965047 -1.209909147 -0.004140585 FBgn0002173 l(2)Su(H) lethal (2) Su(H) http://flybase.org/reports/FBgn0002173 - gene - - - "l(2)su(H), l(2)Su(H)" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0000588 esc extra sexcombs http://flybase.org/reports/FBgn0000588 - protein_coding_gene enzyme activator activity ; GO:0008047 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24459 histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | contributes_to inferred by curator from GO:0035098 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 histone methyltransferase activity (H3-K27 specific) ; GO:0046976 | contributes_to inferred by curator from GO:0035098 histone methyltransferase activity ; GO:0042054 | contributes_to inferred from direct assay nucleosome binding ; GO:0031491 | contributes_to inferred from direct assay histone methyltransferase activity (H3-K27 specific) ; GO:0046976 | contributes_to inferred from mutant phenotype histone H3-K27 methylation ; GO:0070734 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of histone methylation ; GO:0031062 | inferred from direct assay neuron development ; GO:0048666 | inferred from mutant phenotype histone methylation ; GO:0016571 | inferred from direct assay gene silencing ; GO:0016458 | inferred from mutant phenotype inferred from genetic interaction with ph-p muscle organ development ; GO:0007517 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from physical interaction with E(z) chromatin-mediated maintenance of transcription ; GO:0048096 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay ESC/E(Z) complex ; GO:0035098 | inferred from direct assay histone methyltransferase complex ; GO:0035097 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:Q8ST83 polytene chromosome ; GO:0005700 | inferred from direct assay "ESC, dESC, Esc, CG14941, L41867, esc, sc" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG14941 11-Aug-17 DroID_v2017_08 Drer\eed - Cele\mes-6 Xtro\eed Mmus\Eed Hsap\EED " embryonic stage | stage 13 , embryonic stage | stage 8-13 , embryonic stage | early , embryonic stage | 0-8hr " " embryonic brain | restricted

, germ band

,

ubiquitous " " adult stage , embryonic stage , embryonic stage | early " " testis | restricted

, embryonic brain

, neuroblast

" "wild-type,visible,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,non-enhancer of variegation,non-suppressor of variegation,maternal effect,cell autonomous,somatic clone,sterile,lethal,germline clone,rescuable maternal effect,neuroanatomy defective,homeotic,radiation resistant,dominant,viable" "sex comb,photoreceptor cell R1,somatic clone,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,midgut constriction,denticle belt,maternal effect,embryonic abdominal segment 8,ectopic,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,prothoracic segment,mesothoracic segment,metathoracic segment,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,abdominal segment 9,abdominal segment 10,abdominal segment 11,segment,cell autonomous,leg,metathoracic tibial transverse bristle row,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 9,embryonic antennal segment,embryonic maxillary segment,embryonic labial segment,embryonic segment,germline clone,rescuable maternal effect,dendrite & dorsal multidendritic neuron ddaC | somatic clone,dendrite & dorsal multidendritic neuron ddaC | third instar larval stage,embryonic/first instar larval cuticle" FBgn0034708 Vps35 Vacuolar protein sorting 35 http://flybase.org/reports/FBgn0034708 protein_coding_gene "Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab7, Rab9 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95ST2 protein transporter activity ; GO:0008565 | contributes_to inferred from sequence or structural similarity with SGD:S000003690" "retrograde transport, endosome to Golgi ; GO:0042147 | inferred from mutant phenotype retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with SGD:S000003690 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype positive regulation of Wnt protein secretion ; GO:0061357 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from mutant phenotype response to rotenone ; GO:1904647 | inferred from mutant phenotype retrograde transport, endosome to Golgi ; GO:0042147 | inferred by curator from GO:0031647" "endosome ; GO:0005768 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000003690 retromer, cargo-selective complex ; GO:0030906 | inferred from sequence or structural similarity with SGD:S000003690 retromer complex ; GO:0030904 | non-traceable author statement" "Vps35, vps35, dvps35, Dvps35, CG5625, VPS35, DmVps35, DVps35, dVPS35" "IPR005378:Vacuolar protein sorting-associated protein 35, IPR011989:Armadillo-like helical" CG5625 11-Aug-17 DroID_v2017_08 Drer\vps35 Scer\VPS35 Cele\vps-35 Xtro\vps35 Mmus\Vps35 Hsap\VPS35 "partially lethal - majority die,some die during pupal stage,lethal,recessive,melanotic mass phenotype,neuroanatomy defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,maternal effect,visible,somatic clone,neurophysiology defective" "melanotic mass,plasmatocyte,supernumerary,lamellocyte,NMJ bouton,embryonic/larval hemocyte,embryonic/larval dorsal trunk,wing margin,somatic clone,photoreceptor cell,endosome | progressive,lysosome | progressive,follicle cell" FBgn0000463 Dl Delta http://flybase.org/reports/FBgn0000463 "FBgn0011411, FBgn0062130" protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 Notch binding ; GO:0005112 | non-traceable author statement Notch binding ; GO:0005112 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VUX2 receptor binding ; GO:0005102 | non-traceable author statement Notch binding ; GO:0005112 | inferred from physical interaction with N Notch binding ; GO:0005112 | traceable author statement" "mesoderm development=0007498 |... mutant phenotype <> antennal morphogenesis=0048800 |... mutant phenotype <> compound eye development=0048749 | traceable author statement <> ommatidial rotation=0016318 | <> stem cell differentiation=0048863 |... mutant phenotype <> ovarian follicle cell stalk formation=0030713 |... mutant phenotype <> cell adhesion=0007155 | traceable author statement <> Notch signaling pathway=0007219 | traceable author statement <> dorsal/ventral lineage restriction, imaginal disc=0007451 | traceable author statement <> ventral cord development=0007419 | <> R8 cell differentiation=0045465 | <> negative regulation of neurogenesis=0050768 |... mutant phenotype <> Notch signaling pathway=0007219 |... mutant phenotype <> peripheral nervous system development=0007422 | traceable author statement <> imaginal disc-derived wing vein morphogenesis=0008586 | traceable author statement <> lateral inhibition=0046331 | traceable author statement <> oocyte localization involved in germarium-derived egg chamber formation=0030720 |... mutant phenotype <> imaginal disc-derived leg segmentation=0036011 |... mutant phenotype <> Notch signaling pathway=0007219 | <> ovarian follicle cell development=0030707 | traceable author statement <> negative regulation of terminal cell fate specification, open tracheal system=0035155 | <> peripheral nervous system development=0007422 |... mutant phenotype <> compound eye retinal cell programmed cell death=0046667 | traceable author statement <> ectoderm development=0007398 | traceable author statement <> germ-line stem cell population maintenance=0030718 |... mutant phenotype <> oogenesis=0048477 | traceable author statement <> imaginal disc-derived wing morphogenesis=0007476 |... mutant phenotype <> positive regulation of mitotic cell cycle=0045931 |... mutant phenotype <> regulation of R8 cell spacing in compound eye=0045468 | <> R8 cell fate commitment=0007460 | traceable author statement <> nervous system development=0007399 | <> oocyte anterior/posterior axis specification=0007314 | traceable author statement <> wing disc dorsal/ventral pattern formation=0048190 |... mutant phenotype <> asymmetric cell division=0008356 | traceable author statement <> Notch signaling pathway=0007219 |... genetic interaction with mam <> cell fate specification=0001708 | traceable author statement <> apposition of dorsal and ventral imaginal disc-derived wing surfaces=0007475 |... mutant phenotype <> sleep=0030431 |... expression pattern <> sensory organ development=0007423 |... mutant phenotype <> second mitotic wave involved in compound eye morphogenesis=0016330 |... mutant phenotype <> lateral inhibition=0046331 |... mutant phenotype <> oogenesis=0048477 |... mutant phenotype <> open tracheal system development=0007424 | <> actin filament organization=0007015 |... mutant phenotype <> border follicle cell migration=0007298 |... mutant phenotype <> glial cell migration=0008347 |... mutant phenotype <> imaginal disc-derived wing vein specification=0007474 | <> positive regulation of cell proliferation=0008284 |... mutant phenotype <> imaginal disc-derived leg morphogenesis=0007480 |... mutant phenotype <> negative regulation of fusion cell fate specification=0035157 | <> R3/R4 cell fate commitment=0007464 | <> chaeta morphogenesis=0008407 |... mutant phenotype <> establishment of ommatidial planar polarity=0042067 | traceable author statement <> establishment of planar polarity=0001736 | <> ovarian follicle cell development=0030707 |... mutant phenotype <> lateral inhibition=0046331 | <> compound eye cone cell fate commitment=0042676 | traceable author statement" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011651 adherens junction ; GO:0005912 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | traceable author statement cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay endosome ; GO:0005768 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement cell surface ; GO:0009986 | inferred from direct assay endocytic vesicle ; GO:0030139 | inferred from direct assay subapical complex ; GO:0035003 | inferred from direct assay "Dl, CG3619, dmDelta, delta, CT12133, delta D1, 1485/04, 1440/11, 1423/11, 1304/03, 1119/09, 1053/14, 0926/11, 0495/20, D, C1, l(3)j8C3, l(3)92Ab, l(3)05151, anon-WO0118547.269, E(ls)2, EC3-5, DL, Delta" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001774:Delta/Serrate/lag-2 (DSL) protein, IPR001881:EGF-like calcium-binding domain, IPR011651:Notch ligand, N-terminal domain, IPR013032:EGF-like, conserved site, IPR009030:Growth factor receptor cysteine-rich domain" CG3619 11-Aug-17 DroID_v2017_08 "Drer\dlc, Drer\dlb, Drer\dla, Drer\dll4, Drer\dlk2, Drer\dld, Drer\zgc:66449" - "Cele\apx-1, Cele\lag-2, Cele\C37C3.7, Cele\sdz-23, Cele\dsl-4" "Xtro\dll1, Xtro\dlc, Xtro\dll4" "Mmus\Dll4, Mmus\Dll3, Mmus\Dll1, Mmus\Dlk2, Mmus\Umod, Mmus\Gp2" "Hsap\DLL3, Hsap\DLK2, Hsap\UMOD, Hsap\DLL4, Hsap\DLL1, Hsap\GP2" " embryonic stage , embryonic stage | stage >=11 , embryonic stage | stage >=12 , embryonic stage | stage 5-6 , embryonic stage | early , embryonic stage | stage 7 , larval stage | third instar , embryonic stage | stage 11,12 , embryonic stage | stage 4-13 , embryonic stage | stage >=10 , embryonic stage | stage >=13 , embryonic stage | stage 9-11 , embryonic stage | stage 8-11 " " neuroblast

, embryonic peripheral nervous system

, embryonic central nervous system

, ventral neurogenic region

, embryonic stomatogastric nervous system

, organism | 20-40% egg length

, proctodeum

, embryonic/larval hindgut

, optic lobe

, organism | 40-70% egg length

, mesectoderm

, sense organ

, procephalic neurogenic region

,

pair rule , photoreceptor cell R4

, peripheral nervous system

, organism | 60-90% egg length

, stomodeal ganglion

, posterior embryonic/larval midgut

, photoreceptor cell R6

, anterior embryonic/larval midgut

, photoreceptor cell R3

, inclusive hindgut primordium

, eye disc

, ventral midline | precursor

, embryonic/larval tracheal system

, stomatogastric nervous system

, photoreceptor cell R7

, organism | 0-20% egg length

, photoreceptor cell R1

, trachea

, morphogenetic furrow

, ectoderm

" " larval stage , larval stage | third instar , embryonic stage , adult stage && oogenesis stage , pupal stage | early , adult stage && oogenesis stage | stage S11 , prepupal stage , larval stage | first instar , larval stage | second instar , larval stage && pupal stage " " sensory mother cell &&of dorsal mesothoracic disc

, eye disc

, morphogenetic furrow | anterior to

, posterior embryonic/larval midgut

, morphogenetic furrow | posterior to

, embryonic/larval dorsal trunk

, nurse cell

, wing vein L3 | presumptive

, photoreceptor cell R7

, peripodial epithelium

, germarium region 1

, larval outer optic anlage | precursor

, photoreceptor cell R5

, macrochaeta | precursor

, sensillum campaniformium &&of wing vein L2

, embryonic/larval pharynx

, mesectoderm

, anterior embryonic/larval midgut

, centripetally migrating follicle cell

, sensory mother cell &&of microchaeta

, wing vein | presumptive

, germarium region 2

, antenno-maxillary complex

, ommatidial precursor cluster

, larval central nervous system

, follicle cell

, photoreceptor cell R6

, larval labral segment sense organ | precursor

, anterior midgut proper primordium

, scutum | presumptive

, wing hair

, ventral neurogenic region

, photoreceptor cell R8

, procephalic neurogenic region

, macrochaeta

, neurogenic region

, larval inner optic anlage | precursor

, germarium region 3

, embryonic/larval hindgut

, oocyte

, photoreceptor cell R3

, ventral nerve cord

, precursor cell of the stomatogastric nervous system

, proneural cluster &&of microchaeta

, cone cell

, morphogenetic furrow

, dorsal mesothoracic disc | restricted

, embryonic/larval proventriculus

, photoreceptor cell

, antennal disc

, ventral midline

, embryonic/larval lateral trunk

, microchaeta

, glial cell

, amnioproctodeal invagination

, embryonic optic lobe primordium

, photoreceptor cell R1

, photoreceptor cell R4

, wing hair | presumptive

, photoreceptor cell R2

" "visible,dominant,lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,somatic clone,neurogenic phenotype,wild-type,body color defective,cell lethalcell lethal,heat sensitive,female sterile,non-rescuable maternal effect,polyphasic,planar polarity defective,mitotic cell cycle defective,size defective,reduced,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die,hyperplasia,increased cell number,decreased cell number" "posterior scutellar bristle,adult midgut,wing vein,wing,,macrochaeta,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,tarsal segment,metatarsus,eye,embryonic/larval somatic muscle,dMP2 neuron,vMP2 neuron,RP2sib neuron,RP2 motor neuron,Usib neuron,U neuron,ommatidium,embryonic epidermis,embryo,interfollicle cell,rhabdomere,interommatidial bristle,cone cell,ocellus,leg,sex comb,tormogen cell,trichogen cell,proventriculus inner layer primordium,proventriculus intermediate layer primordium,proventriculus outer layer primordium,embryonic proventriculus,keyhole structure,microchaeta,stomatogastric nervous system primordium,scutum,ectoderm,photoreceptor cell,adult thoracic sensillum,embryonic cardioblast,basal cylinder,dorsal hair,filzkorper,embryonic hindgut,crossvein,aCC neuron,pCC neuron,posterior crossvein,five-cell ommatidial precursor cluster,eye-antennal disc,ommatidial precursor cluster,primary pigment cell,secondary pigment cell,tertiary pigment cell,basal stalk,follicle cell,nurse cell,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,hub cell,embryonic/larval corpus cardiacum,border follicle cell,lamina anlage,medulla anlage,larval outer optic anlage,S2 cell-line,anterior embryonic/larval midgut,hub cell | first instar larval stage,morphogenetic furrow,embryonic/larval dorsal vessel,dorsal triple row,medial triple row,ventral triple row,chemosensory ventral triple row bristle,mechanosensory ventral triple row bristle,neuroblast,embryonic/larval central nervous system,embryonic/larval peripheral nervous system,segment,joint,segment border muscle,anterior scutellar bristle,female germline stem cell,trichome of the posterior wing margin,eye disc,egg chamber,oocyte nucleus,scutellar bristle,germline cyst,polar follicle cell,oocyte,dorsal acute muscle,pericardial cell,tendon cell,principal midgut epithelial cell,ventral nervous system,embryonic/first instar larval cuticle,neurosecretory neuron,embryonic/larval dorsal branch,pigment cell,intersegmental nerve,exit glial cell,ovary,lens,antenna,-C253,wing margin,adult heart,dorsal cluster neuron,medulla,hs.PB,germarium cap cell,embryonic/larval lymph gland,crystal cell,pretarsus,wing disc,head,pronotum,postnotum,genitalia,klu-G410,eye disc |,tracheal branch primordium,embryonic/larval dorsal trunk,btl.PS,sense organ,l(3)31-1-31-1,ventral thoracic disc,neur-P72,leg sensillum,mitotic cell cycle,cone cell | pupal stage,mat.‘±Tub67C.THsimVP16,wing blade,peripheral glial cell,-537.4,embryonic/larval neuron,chaeta,germline stem cell" DRSC16648 I 0.478163604 3.397238406 0.276366035 0.470581949 0.411791169 -0.172038097 FBgn0001168 h hairy http://flybase.org/reports/FBgn0001168 "FBgn0011517, FBgn0019807, FBgn0019998" protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 E-box binding ; GO:0070888 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P16371 DNA binding ; GO:0003677 | inferred from direct assay RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with gro inferred from physical interaction with CtBP protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V8P9 transcription factor binding ; GO:0008134 | inferred from physical interaction with gro transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay" "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype posterior head segmentation ; GO:0035289 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay R8 cell fate commitment ; GO:0007460 | non-traceable author statement trunk segmentation ; GO:0035290 | traceable author statement periodic partitioning by pair rule gene ; GO:0007366 | non-traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement salivary gland development ; GO:0007431 | traceable author statement cell morphogenesis ; GO:0000902 | inferred from mutant phenotype periodic partitioning by pair rule gene ; GO:0007366 | traceable author statement regulation of cellular metabolic process ; GO:0031323 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from mutant phenotype tube morphogenesis ; GO:0035239 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype inferred from genetic interaction with hkb nervous system development ; GO:0007399 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype inferred from physical interaction with gro negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement membrane organization ; GO:0061024 | traceable author statement salivary gland morphogenesis ; GO:0007435 | traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0003677 "h, Hairy, CG6494, dDr1, 8247, l(3)08247, brr, l(3)rM384, hry, H, bHLHc14, bHLHb39, HRY" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG6494 11-Aug-17 DroID_v2017_08 "Drer\hey2, Drer\her2, Drer\heyl, Drer\her12, Drer\her4.2, Drer\bhlhe40, Drer\LOC100149863, Drer\her1, Drer\hes2.2, Drer\her11, Drer\her5, Drer\her8a, Drer\her15.1, Drer\hey1, Drer\helt, Drer\her15.2, Drer\hes6, Drer\her13, Drer\her3, Drer\her8.2, Drer\her7, Drer\her6, Drer\hes2.1, Drer\her4.4, Drer\her9, Drer\her4.3, Drer\bhlhe41" Scer\PHO4 "Cele\hlh-25, Cele\lin-22, Cele\hlh-27, Cele\F52G2.3" "Xtro\bhlhe40, Xtro\hes1, Xtro\hes4, Xtro\hey2, Xtro\hes7.1, Xtro\hes2, Xtro\bhlhe41, Xtro\hes6.1, Xtro\hey1, Xtro\hes7.2" "Mmus\Hes5, Mmus\Hes6, Mmus\Helt, Mmus\Hey2, Mmus\Hey1, Mmus\Bhlhe40, Mmus\Hes1, Mmus\Heyl, Mmus\Hes2, Mmus\Hes3, Mmus\Bhlhe41, Mmus\Hes7" "Hsap\HES5, Hsap\HES2, Hsap\HEY1, Hsap\HES1, Hsap\HES4, Hsap\BHLHE40, Hsap\HES3, Hsap\HEYL, Hsap\BHLHE41, Hsap\HEY2, Hsap\HES6, Hsap\HES7, Hsap\HELT" " embryonic stage | late , embryonic stage " adult salivary gland primordium

" embryonic stage | blastoderm , embryonic stage | cycle 14 , embryonic stage | stage 11-14 , embryonic stage | stage 14-16 , embryonic stage | stage 10 , embryonic stage | <=stage 9 , embryonic stage | stage 10, 11 , embryonic stage | stage 9-16 , embryonic stage | stage <=9 , embryonic stage | stage 5 " " organism | striped

,

pair rule , somatic mesoderm

, embryonic hindgut

, stomodeum

, organism | 80-100% egg length

, embryonic/larval tracheal pit

, proctodeum

, median tooth | precursor

, anal plate

, visceral mesoderm

, labral segment

" "pair rule phenotype,lethal,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,somatic clone,wild-type,female,male,partially lethal - majority die,embryonic/larval segmentation phenotype,reduced,dominant" "embryonic/first instar larval cuticle,macrochaeta,embryo,wing,posterior compartment,stomatogastric nervous system,cuticle,segment,scutellum & macrochaeta,haltere & macrochaeta,head capsule & macrochaeta,ectopic,larval abdominal segment 4,adult abdominal segment 4,neuron,wing sensillum,wing vein L2 & macrochaeta & adult,microchaeta & mesothoracic tergum | supernumerary,microchaeta | ectopic & scutellum,medial triple row,wing margin bristle,wing hair,wing hair & wing vein L2,dorsal triple row,chemosensory ventral triple row bristle,wing & neuron & glial cell,glial cell,wing vein,wing vein & wing sensillum | ectopic | somatic clone,adult thorax & microchaeta | ectopic | somatic clone,mesothoracic tergum & macrochaeta | ectopic | conditional cs,wing cell,wing vein L2,eye,mouthpart,female,head,abdomen,embryonic/first instar larval cuticle & mesothoracic segment,presumptive embryonic salivary gland,larval midgut & embryo & epidermis,larval abdominal segment 2,larval abdominal segment 6,larval abdominal segment 8,denticle belt,embryonic labial segment,wing & macrochaeta & adult,somatic clone,wing & macrochaeta | somatic clone,tracheal system,rhabdomere,embryonic epidermis,extended germ band embryo,prothoracic segment,mesothoracic segment,metathoracic segment,abdominal segment 1,abdominal segment 2,larval metathoracic segment,larval abdominal segment 7,larval abdominal segment 3,larval head,larval abdominal segment 1,larval abdominal segment 5,larval mesothoracic segment,denticle,mesothoracic tarsal bristle,mesothoracic metatarsus,prothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic/first instar larval cuticle & abdominal segment 1,embryonic/first instar larval cuticle & abdominal segment 3,embryonic/first instar larval cuticle & abdominal segment 5,embryonic/first instar larval cuticle & abdominal segment 7,abdominal segment 4,abdominal 9 ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,pigment cell" FBgn0028683 spt4 spt4 http://flybase.org/reports/FBgn0028683 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR009287 RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000306261 single-stranded RNA binding ; GO:0003727 | inferred from biological aspect of ancestor with PANTHER:PTN000306261 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000306261 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with UniProtKB:P63272" "negative regulation of DNA-templated transcription, elongation ; GO:0032785 | inferred from direct assay positive regulation of DNA-templated transcription, elongation ; GO:0032786 | inferred from sequence or structural similarity with UniProtKB:P63272 mRNA processing ; GO:0006397 | inferred from biological aspect of ancestor with PANTHER:PTN000306261 chromatin organization ; GO:0006325 | inferred from biological aspect of ancestor with PANTHER:PTN000306261 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay negative regulation of DNA-templated transcription, elongation ; GO:0032785 | inferred from sequence or structural similarity with UniProtKB:P63272 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from sequence or structural similarity with UniProtKB:P63272 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with UniProtKB:P63272 regulation of transcription elongation from RNA polymerase II promoter ; GO:0034243 | inferred from biological aspect of ancestor with PANTHER:PTN000306261 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with UniProtKB:P63272" transcription elongation factor complex ; GO:0008023 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P63272 DSIF complex ; GO:0032044 | inferred from biological aspect of ancestor with PANTHER:PTN000306261 polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay "142904_at, DSIF, Spt4, dDSIF, Dspt4, SPT4, CG12372, l(2)k05316, spt4, dspt4" "IPR009287:Transcription initiation Spt4, IPR013088:Zinc finger, NHR/GATA-type, IPR029040:RNA polymerase subunit RPABC4/transcription elongation factor Spt4, IPR022800:Spt4/RpoE2 zinc finger" CG12372 11-Aug-17 DroID_v2017_08 Drer\supt4h1 Scer\SPT4 Cele\spt-4 Xtro\supt4h1 "Mmus\Supt4b, Mmus\Supt4a" Hsap\SUPT4H1 "lethal,recessive,partially lethal - majority die" FBgn0028988 Spn42Dd Serpin 42Dd http://flybase.org/reports/FBgn0028988 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from mutant phenotype negative regulation of endopeptidase activity ; GO:0010951 | inferred from direct assay negative regulation of proteolysis ; GO:0045861 | inferred from sequence model regulation of antimicrobial peptide production ; GO:0002784 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "sp1, CG9456, Spn42Dd, Spn1" "IPR000215:Serpin family, IPR023796:Serpin domain" CG9456 11-Aug-17 DroID_v2017_08 "Drer\serpine3, Drer\zgc:173729, Drer\serpinb1l3, Drer\serpinb1l1, Drer\serpinh2, Drer\serpina1l, Drer\serpind1, Drer\si:ch1073-416d2.3, Drer\si:ch211-186e20.7, Drer\serpini1, Drer\serpinb1l2, Drer\serpinb1, Drer\serpinc1, Drer\serpinb1l4, Drer\serpinh1a, Drer\serpine2, Drer\serpinh1b, Drer\serpina7, Drer\serpinb14, Drer\zgc:174259, Drer\serpina10a, Drer\serpine1" - "Cele\srp-8, Cele\srp-1, Cele\srp-3, Cele\srp-6, Cele\srp-7, Cele\srp-2" "Xtro\serpini2, Xtro\serpinb11, Xtro\serpina10, Xtro\serpina3k, Xtro\serpine2, Xtro\serpina3m, Xtro\serpini1, Xtro\serpine1, Xtro\serpinb1, Xtro\serpind1, Xtro\serpina1, Xtro\serpina3, Xtro\serpinb5, Xtro\serpinb6, Xtro\serpinc1, Xtro\serpinb4" "Mmus\Serpinb5, Mmus\Serpinb3c, Mmus\Serpinb1b, Mmus\Serpine1, Mmus\Serpinb6d, Mmus\Serpina11, Mmus\Serpinb9e, Mmus\Serpinb6e, Mmus\Serpinb11, Mmus\Serpinb9d, Mmus\Serpind1, Mmus\Serpina1e, Mmus\Serpina3f, Mmus\Serpinb9, Mmus\Serpina3g, Mmus\Serpina10, Mmus\Serpina6, Mmus\Serpinb13, Mmus\Serpina3k, Mmus\Serpinb6b, Mmus\Serpinb10, Mmus\Serpina1c, Mmus\Serpina3j, Mmus\Serpinb1a, Mmus\Serpinb7, Mmus\Serpina7, Mmus\Serpinc1, Mmus\Serpini1, Mmus\Serpinb2, Mmus\Serpinb9c, Mmus\Serpinb9g, Mmus\Serpina3c, Mmus\Serpinb9f, Mmus\Serping1, Mmus\Serpinb8, Mmus\Serpina3a, Mmus\Gm11397, Mmus\Serpinb1c, Mmus\Serpina16, Mmus\Serpina3i, Mmus\Serpina1d, Mmus\Serpina12, Mmus\Serpine2, Mmus\Serpina9, Mmus\Serpina1a, Mmus\Serpini2, Mmus\Serpine3, Mmus\Serpinb12, Mmus\Serpinb9b, Mmus\Serpina3n, Mmus\Serpina5, Mmus\Serpinb3b, Mmus\Serpinb6a, Mmus\Serpinb3a, Mmus\Serpinb3d, Mmus\Serpinh1, Mmus\Serpinb6c" "Hsap\SERPIND1, Hsap\SERPINC1, Hsap\SERPINE3, Hsap\SERPINA9, Hsap\SERPINB1, Hsap\SERPINA1, Hsap\SERPINE1, Hsap\SERPINE2, Hsap\SERPINA4, Hsap\SERPING1, Hsap\SERPINB4, Hsap\SERPINB11, Hsap\SERPINB8, Hsap\SERPINB12, Hsap\SERPINA5, Hsap\SERPINB6, Hsap\HMSD, Hsap\SERPINB5, Hsap\SERPINB7, Hsap\SERPINA11, Hsap\SERPINA3, Hsap\SERPINA7, Hsap\SERPINB2, Hsap\SERPINB13, Hsap\SERPINB9, Hsap\SERPINA6, Hsap\SERPINI1, Hsap\SERPINH1, Hsap\SERPINA12, Hsap\SERPINB10, Hsap\SERPINA10, Hsap\SERPINB3, Hsap\SERPINI2" "immune response defective,viable" FBgn0060359 l(3)S140207 lethal (3) S140207 http://flybase.org/reports/FBgn0060359 gene - - - "1402/07, l(3)S140207" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0038126 CG8483 - http://flybase.org/reports/FBgn0038126 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR018244 extracellular region ; GO:0005576 | inferred from sequence model CG8483 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR002413:Ves allergen, IPR018244:Allergen V5/Tpx-1-related, conserved site, IPR014044:CAP domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8483 11-Aug-17 DroID_v2017_08 "Drer\glipr2l, Drer\crispld2, Drer\glipr1b, Drer\glipr2, Drer\crispld1a, Drer\crispld1b, Drer\pi15a, Drer\LOC100536500, Drer\pi15b, Drer\r3hdml" "Scer\PRY1, Scer\PRY2, Scer\PRY3" "Cele\lon-1, Cele\scl-23, Cele\scl-20, Cele\scl-2" "Xtro\crispld2, Xtro\MGC108118, Xtro\glipr2, Xtro\crisp3, Xtro\pi15, Xtro\r3hdml, Xtro\crisp2-like, Xtro\crisp2, Xtro\crisp1" "Mmus\Glipr1, Mmus\Crisp2, Mmus\Crispld2, Mmus\Glipr2, Mmus\Crispld1, Mmus\Crisp4, Mmus\R3hdml, Mmus\Clec18a, Mmus\Pi16, Mmus\Crisp3, Mmus\Glipr1l1, Mmus\Pi15, Mmus\Glipr1l2, Mmus\Crisp1" "Hsap\CRISP2, Hsap\CRISP3, Hsap\CLEC18B, Hsap\GLIPR2, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\CLEC18C, Hsap\CLEC18A, Hsap\GLIPR1, Hsap\CRISP1, Hsap\PI15, Hsap\R3HDML, Hsap\PI16, Hsap\CRISPLD1" "lethal,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0013471 l(1)10P4 lethal (1) 10P4 http://flybase.org/reports/FBgn0013471 - gene - - - l(1)10P4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0001179 hay haywire http://flybase.org/reports/FBgn0001179 "FBgn0004376, FBgn0015830" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006935 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006935 helicase activity ; GO:0004386 | inferred from sequence or structural similarity with HGNC:3435 transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent 3'-5' DNA helicase activity ; GO:0043140 | inferred from sequence or structural similarity with HGNC:3435" "transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity with HGNC:3435 regulation of transcription, DNA-templated ; GO:0006355 | inferred from genetic interaction with hfp regulation of growth ; GO:0040008 | inferred from genetic interaction with hfp response to UV ; GO:0009411 | inferred from mutant phenotype transcriptional open complex formation at RNA polymerase II promoter ; GO:0001113 | inferred from sequence or structural similarity with HGNC:3435 regulation of cell proliferation ; GO:0042127 | inferred from genetic interaction with hfp regulation of RNA polymerase II regulatory region sequence-specific DNA binding ; GO:1903025 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:3435 inferred from sequence or structural similarity with SGD:S000001405 promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from sequence or structural similarity with HGNC:3435 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" "holo TFIIH complex ; GO:0005675 | inferred from physical interaction with CycH, Mat1, mrn, Xpd, Cdk7 nucleus ; GO:0005634 | inferred by curator from GO:0000381 holo TFIIH complex ; GO:0005675 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:3435 inferred from sequence or structural similarity with SGD:S000001405 nucleus ; GO:0005634 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:3435" "ERCC3, XPB, TFIIH, i50, CG8019, Xpb/hay, hwr, DhXPB, DhR25, DmXPB, nc2, ms(3)nc2, hay, Hay, Xpb" "IPR001161:Helicase XPB/Ssl2, IPR001650:Helicase, C-terminal, IPR006935:Helicase/UvrB, N-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR032830:Helicase XPB/Ssl2, N-terminal domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR032438:ERCC3/RAD25/XPB helicase, C-terminal domain" CG8019 11-Aug-17 DroID_v2017_08 Drer\ercc3 Scer\SSL2 Cele\xpb-1 Xtro\ercc3 Mmus\Ercc3 Hsap\ERCC3 embryonic stage -- adult stage "radiation sensitive,wild-type,viable,male sterile,male fertile,meiotic cell cycle defective,male,recessive,lethal,visible,partially,heat sensitive,female sterile,female fertile,reduced,partially lethal - majority die,increased cell death" "chaeta,wing,macrochaeta,microchaeta,adult abdomen & endocuticle,wing margin,meiotic cell cycle | male,embryonic/larval central nervous system,imaginal disc,adult abdomen & endocuticlelxd6)" DRSC11354 IK 3.361916789 0.454441399 -0.628132933 0.467182685 0.757526396 1.869605519 FBgn0040297 Nhe2 Na[+]/H[+] hydrogen exchanger 2 http://flybase.org/reports/FBgn0040297 protein_coding_gene potassium:proton antiporter activity ; GO:0015386 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 sodium:proton antiporter activity ; GO:0015385 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 regulation of cellular pH ; GO:0030641 | inferred from mutant phenotype potassium ion transmembrane transport ; GO:0071805 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 sodium ion import across plasma membrane ; GO:0098719 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 cellular ion homeostasis ; GO:0006873 | inferred from expression pattern "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004709, InterPro:IPR006153, InterPro:IPR018422 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000011605" "NHE2, DmNHE2, CG9255, CG9256, Nhe2, nhe2, Dnhe2, DNhe2" "IPR018422:Cation/H+ exchanger, CPA1 family, IPR004709:Na+/H+ exchanger, IPR006153:Cation/H+ exchanger" CG9256 11-Aug-17 DroID_v2017_08 "Drer\slc9a3.1, Drer\slc9a5, Drer\slc9a2, Drer\slc9a3.2" Scer\NHX1 "Cele\nhx-9, Cele\nhx-2, Cele\nhx-4, Cele\nhx-1, Cele\nhx-3, Cele\nhx-6, Cele\pbo-4" "Xtro\slc9a1, Xtro\slc9a5, Xtro\LOC100488264" "Mmus\Slc9a1, Mmus\Slc9a3, Mmus\Slc9a4, Mmus\Slc9a2, Mmus\Slc9a5" "Hsap\SLC9A3, Hsap\SLC9A4, Hsap\SLC9A1, Hsap\SLC9A2, Hsap\SLC9A5" "viable,fertile,cell lethalcell lethal,recessive,somatic clone,lethal - all die before end of larval stage,some die during larval stage,planar polarity defective" "embryonic/larval digestive system,embryonic/larval fat body,ommatidium,eye,eye photoreceptor cell" DRSC03172 E 1.124920811 -0.018991303 1.789548173 -0.296814038 0.764371682 -0.201884982 FBgn0060836 l(3)S049701 lethal (3) S049701 http://flybase.org/reports/FBgn0060836 gene - - - "l(3)S049706, 0497/06, l(3)S049706a, l(3)S049701" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0000347 condensed condensed http://flybase.org/reports/FBgn0000347 - gene - - - "condensed, con" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,partially lethal - majority die,sterile,male" "thorax,abdomen,eye,wing,macrochaeta,posterior scutellar bristle,posterior vertical bristle" FBgn0034354 GstE11 Glutathione S transferase E11 http://flybase.org/reports/FBgn0034354 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "cg5224, CG5224, GstE11, gste11, GSTE11" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG5224 11-Aug-17 DroID_v2017_08 "Drer\gstr, Drer\eef1e1, Drer\vars, Drer\mars, Drer\gstt1b, Drer\eef1g, Drer\gstt2, Drer\gstt1a" "Scer\URE2, Scer\GTT1, Scer\TEF4, Scer\GTT2, Scer\CAM1, Scer\YGR201C" - "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Gstt1, Mmus\Gstt4, Mmus\Vars, Mmus\Eef1e1, Mmus\Gstt3, Mmus\Mars, Mmus\Gstt2, Mmus\Eef1g" "Hsap\EEF1G, Hsap\GSTT1, Hsap\GSTT2, Hsap\VARS, Hsap\MARS, Hsap\GSTT2B, Hsap\EEF1E1" "lethal,neuroanatomy defective,viable,visible,fertile" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0005190 l(2)S50 lethal of Seto 50 http://flybase.org/reports/FBgn0005190 - gene - - - l(2)S50 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "eye,genitalia,epidermis" FBgn0021906 RFeSP Rieske iron-sulfur protein http://flybase.org/reports/FBgn0021906 "FBgn0025542, FBgn0031352" protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR017941 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:P47985" "mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:P47985" mitochondrion ; GO:0005739 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:P47985 "RfeSP, CG7361, H, l(2)k11704, anon-EST:Posey219, RFeSP, RISP, Noble, UCRI, UQCR-RFeSP" "IPR004192:Ubiquinol cytochrome reductase, transmembrane domain, IPR006317:Ubiquinol-cytochrome c reductase, iron-sulphur subunit, IPR014349:Rieske iron-sulphur protein, IPR017941:Rieske [2Fe-2S] iron-sulphur domain, IPR005805:Rieske iron-sulphur protein, C-terminal" CG7361 11-Aug-17 DroID_v2017_08 Drer\uqcrfs1 Scer\RIP1 Cele\isp-1 Xtro\uqcrfs1 Mmus\Uqcrfs1 Hsap\UQCRFS1 "lethal,recessive" lysosome & larval fat body | somatic clone | cell autonomous DRSC00702 IE -0.584617391 -1.511153549 -2.110558686 -0.581680779 0.025972042 0.911318913 FBgn0028003 l(3)S119307b lethal (3) S119307b http://flybase.org/reports/FBgn0028003 gene - - - "1337/05, l(3)S119307, l(3)S119307b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0043854 slam slow as molasses http://flybase.org/reports/FBgn0043854 protein_coding_gene - germ cell migration ; GO:0008354 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype cellularization ; GO:0007349 | traceable author statement cleavage furrow formation ; GO:0036089 | inferred from genetic interaction with nullo membrane organization ; GO:0061024 | non-traceable author statement cleavage furrow ingression ; GO:0036090 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement protein localization ; GO:0008104 | non-traceable author statement cleavage furrow ; GO:0032154 | inferred from direct assay "Slam, CG9506, wdo, slam" - CG9506 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | embryonic cycle 13-14 embryonic stage | cycle 14 furrow canal

viable "germline cell,embryonic/larval midgut primordium,gonadal sheath proper primordium,cycle 14 embryo,furrow canal,germline clone" DRSC03240 I 1.596482818 -0.027722038 -0.103578729 1.21276141 -0.001593993 -0.50012749 FBgn0010395 Itgbn Integrin betanu subunit http://flybase.org/reports/FBgn0010395 "FBgn0010216, FBgn0025116" protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with scb cell adhesion molecule binding ; GO:0050839 | traceable author statement receptor activity ; GO:0004872 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from sequence or structural similarity with mys negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype cell-matrix adhesion ; GO:0007160 | traceable author statement apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | traceable author statement muscle cell cellular homeostasis ; GO:0046716 | inferred from genetic interaction with Dg inferred from genetic interaction with Dys integrin complex ; GO:0008305 | non-traceable author statement integrin complex ; GO:0008305 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from direct assay integrin complex ; GO:0008305 | traceable author statement integrin complex ; GO:0008305 | inferred from direct assay integrin complex ; GO:0008305 | inferred from sequence or structural similarity with mys "betanu, betav, CG1762, CT5192, beta[[v]], Beta[[nu]], betaInt[nu], beta[nu]-integrin, betaInt-nu, Fly betanu, betaInt, betaV-integrin, beta-nu, betaInt nu, Itgbn, Itgbetanu, betagr;-nu" "IPR002035:von Willebrand factor, type A, IPR002369:Integrin beta subunit, VWA domain, IPR015812:Integrin beta subunit, IPR032695:Integrin domain, IPR014836:Integrin beta subunit, cytoplasmic domain, IPR013111:EGF-like domain, extracellular" CG1762 11-Aug-17 DroID_v2017_08 "Drer\itgb3a, Drer\itgb5, Drer\itgb1b.1, Drer\itgb7, Drer\itgb6, Drer\im:7156467, Drer\itgb3b, Drer\itgbl1, Drer\itgb2, Drer\itgb1a, Drer\itgb1b.2, Drer\itgb8, Drer\itgb1b, Drer\itgb4" - "Cele\pat-3, Cele\C05D9.3" "Xtro\itgb1, Xtro\itgbl1, Xtro\itgb6, Xtro\itgb4, Xtro\itgb2, Xtro\itgb7, Xtro\itgb8, Xtro\itgb3" "Mmus\Itgb8, Mmus\Itgb2l, Mmus\Itgb1, Mmus\Itgb7, Mmus\Itgbl1, Mmus\Itgb4, Mmus\Itgb3, Mmus\Itgb6, Mmus\Itgb5, Mmus\Itgb2" "Hsap\ITGB5, Hsap\ITGB3, Hsap\ITGB7, Hsap\ITGB2, Hsap\ITGB1, Hsap\ITGBL1, Hsap\ITGB6, Hsap\ITGB8, Hsap\ITGB4" " embryonic stage , embryonic stage -- adult stage " endoderm &&of midgut

" larval stage , embryonic stage " " embryonic/larval proventriculus

, endoderm &&of midgut

, hindgut imaginal ring

, midgut imaginal island

, gastric caecum

" "viable,smell perception defective,immune response defective,sleep defective,fertile,neuroanatomy defective,visible" "NMJ bouton,supernumerary,neuromuscular junction | third instar larval stage,intersegmental nerve,anterior fascicle & synapse,neuromuscular junction | third instar larval stageelav.PU,trichogen cell,embryonic hemocyte,embryonic/larval hemocyte | third instar larval stage" FBgn0035798 frac faulty attraction http://flybase.org/reports/FBgn0035798 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" axon target recognition ; GO:0007412 | inferred from mutant phenotype - "CT16044, CG7526, frac" "IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000436:Sushi/SCR/CCP domain, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR003410:HYR domain, IPR013032:EGF-like, conserved site, IPR018097:EGF-like calcium-binding, conserved site, IPR013783:Immunoglobulin-like fold, IPR011042:Six-bladed beta-propeller, TolB-like, IPR009030:Growth factor receptor cysteine-rich domain, IPR026823:Complement Clr-like EGF domain" CG7526 11-Aug-17 DroID_v2017_08 "Drer\fbln5, Drer\notch2, Drer\notch1b, Drer\fbln2, Drer\si:ch211-221n20.8, Drer\crb1, Drer\fbn2b, Drer\LOC562634, Drer\fbln1, Drer\crb2b, Drer\fbn2a, Drer\fbln7, Drer\notch3, Drer\crb2a, Drer\notch1a" - "Cele\fbn-1, Cele\crb-1, Cele\lin-12, Cele\mua-3, Cele\fbl-1, Cele\mup-4, Cele\glp-1, Cele\eat-20, Cele\F58E6.13" "Xtro\scube2, Xtro\fbn3, Xtro\fbln5, Xtro\scube1, Xtro\svep1" "Mmus\Matn2, Mmus\Scube1, Mmus\Vwa2, Mmus\Fbln7, Mmus\Notch1, Mmus\Cd248, Mmus\Fbn1, Mmus\Scube2, Mmus\Col6a5, Mmus\Egfem1, Mmus\Notch4, Mmus\Col6a3, Mmus\Fbn2, Mmus\Cd93, Mmus\Fbln1, Mmus\Notch3, Mmus\Notch2, Mmus\Crb1, Mmus\Fbln2, Mmus\Crb2, Mmus\Fbln5, Mmus\Thbd, Mmus\Scube3" "Hsap\NOTCH2, Hsap\THBD, Hsap\NOTCH1, Hsap\FBLN7, Hsap\NOTCH3, Hsap\CD248, Hsap\FBN2, Hsap\SCUBE1, Hsap\CRB1, Hsap\UMODL1, Hsap\COL6A5, Hsap\FBLN5, Hsap\CD93, Hsap\SCUBE3, Hsap\SCUBE2, Hsap\FBLN1, Hsap\VWA2, Hsap\FBN3, Hsap\NOTCH4, Hsap\MATN2, Hsap\EYS, Hsap\FBN1, Hsap\LTBP2, Hsap\CRB2, Hsap\FBLN2" "viable,fertile,neuroanatomy defective" "intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,intersegmental nerve branch ISNb of A1-7 | embryonic stage" FBgn0028233 l(3)S003606 lethal (3) S003606 http://flybase.org/reports/FBgn0028233 gene - - - "0036/06, l(3)S003606, l(3)s003606" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0001526 l(1)11Eb lethal (1) 11Eb http://flybase.org/reports/FBgn0001526 - gene - - - l(1)11Eb - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033755 ClC-b Chloride channel-b http://flybase.org/reports/FBgn0033755 protein_coding_gene voltage-gated chloride channel activity ; GO:0005247 | inferred from biological aspect of ancestor with PANTHER:PTN001363397 chloride transmembrane transporter activity ; GO:0015108 | inferred from mutant phenotype chloride channel activity ; GO:0005254 | inferred from sequence or structural similarity with ClC-a chloride transmembrane transport ; GO:1902476 | inferred from mutant phenotype sensory perception of touch ; GO:0050975 | inferred from mutant phenotype chloride transmembrane transport ; GO:1902476 | inferred from sequence or structural similarity with ClC-a late endosome ; GO:0005770 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with ClC-a "CG8594, ClC-b, DmClCb, DmClC-b, Clcn7" "IPR000644:CBS domain, IPR001807:Chloride channel, voltage gated, IPR014743:Chloride channel, core" CG8594 11-Aug-17 DroID_v2017_08 "Drer\clcn6, Drer\clcn7" Scer\GEF1 Cele\clh-6 "Xtro\clcn7, Xtro\clcn6" "Mmus\Clcn6, Mmus\Clcn7" "Hsap\CLCN7, Hsap\CLCN6" "viable,touch sensitivity defective,lethal" DRSC07220 K 0.53449946 0.000177269 0.918218065 -0.233290482 0.716640119 2.627080407 FBgn0039932 fuss fussel http://flybase.org/reports/FBgn0039932 protein_coding_gene co-SMAD binding ; GO:0070410 | inferred from physical interaction with Med neuron development ; GO:0048666 | inferred from biological aspect of ancestor with PANTHER:PTN000000299 negative regulation of cell differentiation ; GO:0045596 | inferred from biological aspect of ancestor with PANTHER:PTN000000299 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from biological aspect of ancestor with PANTHER:PTN000000299 negative regulation of BMP signaling pathway ; GO:0030514 | inferred from mutant phenotype inferred from genetic interaction with sax inferred from genetic interaction with Mad inferred from genetic interaction with Med cytoplasm ; GO:0005737 | inferred from direct assay "CG11093, fuss, CORL" "IPR003380:Transforming protein Ski, IPR009061:Putative DNA-binding domain, IPR010919:SAND domain-like, IPR014890:c-SKI SMAD4-binding domain, IPR023216:Transcription regulator SKI/SnoN" CG11093 11-Aug-17 DroID_v2017_08 "Drer\skor1a, Drer\skor1b, Drer\zgc:153395" - Cele\daf-5 Xtro\skor1 "Mmus\Skor1, Mmus\Skor2" "Hsap\SKOR2, Hsap\SKOR1" "viable,lethal,male limited,partially lethal - majority die,female limited,size defective,developmental rate defective,short lived,female semi-fertile" "wing,wing vein,wing vein L2,wing vein L5,posterior crossvein,sensillum campaniformium of dorsal radius,alpha/beta Kenyon cell,gamma Kenyon cell,adult mushroom body,vertical lobe of adult mushroom body" DRSC21452 I -0.818645365 -1.938636718 0.121231071 0.390358204 -0.920554847 0.406624597 FBgn0061121 l(3)S005005 lethal (3) S005005 http://flybase.org/reports/FBgn0061121 gene - - - "0050/05, l(3)S005005" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003132 Pp1-13C Protein phosphatase 1 at 13C http://flybase.org/reports/FBgn0003132 FBgn0030632 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from direct assay protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from direct assay sperm competition ; GO:0046692 | inferred from mutant phenotype protein phosphatase type 1 complex ; GO:0000164 | inferred from sequence or structural similarity "PP1, DmPp1-13C, pp1-13C, PP1alpha13C, PP1c, PP1 13C, CG9156, PP13C, Pp1, Pp1-13C, PP1alpha-13C, 13C, PP1 beta13c, PP1-13C" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like, IPR031675:Serine-threonine protein phosphatase, N-terminal" CG9156 11-Aug-17 DroID_v2017_08 "Drer\ppp1cb, Drer\ppp1cab, Drer\ppp1cc, Drer\ppp1caa" "Scer\PPZ1, Scer\GLC7, Scer\PPZ2, Scer\PPQ1" "Cele\gsp-1, Cele\gsp-2, Cele\F52H3.6, Cele\ZK938.1, Cele\T25B9.2, Cele\pph-1, Cele\F20D6.6" "Xtro\ppp1cb, Xtro\ppp1ca, Xtro\ppp1cc" "Mmus\Ppp1cc, Mmus\Ppp1ca, Mmus\Ppp1cb, Mmus\Gm5601" "Hsap\PPP1CC, Hsap\PPP1CA, Hsap\PPP1CB" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC20269 IE 2.46639853 -1.745927738 4.362067769 -2.283781921 -0.879603221 0.159815629 FBgn0002715 mei-S332 meiotic from via Salaria 332 http://flybase.org/reports/FBgn0002715 FBgn0046271 protein_coding_gene molecular_function ; GO:0003674 | no biological data available male meiosis sister chromatid cohesion ; GO:0007065 | inferred from expression pattern female meiotic division ; GO:0007143 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from direct assay meiotic chromosome segregation ; GO:0045132 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype "condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay pericentric heterochromatin ; GO:0005721 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay" "MEI-S332, MeiS332, mei-S322, mei-s332, meiS332, meiS322, BEST:LD13774, CG5303, mei-S332, MEI-S322, Mei-S332, Mei-S332/Shugoshin" "IPR011515:Shugoshin, C-terminal, IPR011516:Shugoshin, N-terminal coiled-coil domain" CG5303 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage--adult stage , oogenesis stage && adult stage | female , spermatogenesis && adult stage , embryonic stage -- adult stage " " ovary

, testis

" "long lived,female limited,starvation stress response defective,temperature response defective,wild-type,meiotic cell cycle defective,recessive,mitotic cell cycle defective,male sterile,viable,semidominant,lethal,increased cell death" "meiosis II | female,neuroblast & mitotic cell cycleX58-6),meiosis II | male,mitosis,imaginal disc,wing disc,neuroblast & mitotic cell cycle69B" FBgn0033673 CG8298 - http://flybase.org/reports/FBgn0033673 protein_coding_gene glycerol kinase activity ; GO:0004370 | NOT inferred from key residues glycerol-3-phosphate biosynthetic process ; GO:0046167 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 glycerol metabolic process ; GO:0006071 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 triglyceride metabolic process ; GO:0006641 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000023394 CG8298 "IPR018483:Carbohydrate kinase, FGGY, conserved site, IPR018484:Carbohydrate kinase, FGGY, N-terminal, IPR018485:Carbohydrate kinase, FGGY, C-terminal" CG8298 11-Aug-17 DroID_v2017_08 "Drer\gk5, Drer\zgc:172295" Scer\GUT1 Cele\R11F4.1 Xtro\gk "Mmus\Gk2, Mmus\Gykl1, Mmus\Shpk, Mmus\Gk, Mmus\Gk5" "Hsap\GK, Hsap\GK2, Hsap\SHPK, Hsap\GK5" viable FBgn0013674 mt:CoI mitochondrial Cytochrome c oxidase subunit I http://flybase.org/reports/FBgn0013674 "FBgn0002867, FBgn0025247" protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR000883 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR000883 cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000046094 "regulation of neuron death ; GO:1901214 | inferred from mutant phenotype sleep ; GO:0030431 | traceable author statement aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000046094 mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000046096 electron transport coupled proton transport ; GO:0015990 | inferred from biological aspect of ancestor with PANTHER:PTN000046094" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000883 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000046096 "CG34067, COX, COI, CO I, I, Cyt.ox.I, coxI, CoI, CO, anon-EST:fe1F8, mt:CoI, COXI, CO1, cox1, mt-CO1, CcO subunit I, Co I, coI, COX I, COX1, C-IV s.1, mt:CoxI, cox I, Co-I" "IPR000883:Cytochrome c oxidase subunit I, IPR033944:Cytochrome c oxidase subunit I domain, IPR023615:Cytochrome c oxidase, subunit I, copper-binding site, IPR023616:Cytochrome c oxidase-like, subunit I domain" CG34067 11-Aug-17 DroID_v2017_08 Drer\COX1 "Scer\AI3, Scer\AI4, Scer\AI5_ALPHA, Scer\COX1" Cele\COX1 Xtro\COX1 Mmus\COX1 Hsap\COX1 "lethal - all die during P-stage,heat sensitive,viable,short lived,male sterile,neuroanatomy defective,female semi-sterile,locomotor behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,sterile" "germarium region 2b,heat sensitive,mechanosensory chaeta,rhabdomere,ommatidium,photoreceptor cell,flight muscle,eye" FBgn0259601 B0079 - http://flybase.org/reports/FBgn0259601 gene - - - B0079 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "anterior crossvein,wing vein L3,wing,antennal segment,arista" FBgn0028852 CG15262 - http://flybase.org/reports/FBgn0028852 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR007282 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 negative regulation of translation ; GO:0017148 | inferred from biological aspect of ancestor with PANTHER:PTN000595684" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR007282 CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 "BG:DS07851.5, CG15262" IPR007282:NOT2/NOT3/NOT5 CG15262 11-Aug-17 DroID_v2017_08 Drer\cnot2 Scer\CDC36 "Cele\tag-153, Cele\ntl-2" Xtro\cnot2 Mmus\Cnot2 Hsap\CNOT2 viable FBgn0043900 pygo pygopus http://flybase.org/reports/FBgn0043900 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 RNA polymerase II transcription coactivator activity ; GO:0001105 | contributes_to inferred from physical interaction with arm inferred from physical interaction with lgs "imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from physical interaction with UniProtKB:P18824 inferred from physical interaction with UniProtKB:Q961D9 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from physical interaction with UniProtKB:P18824 inferred from physical interaction with UniProtKB:Q961D9 delamination ; GO:0060232 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from genetic interaction with arm eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype inferred from genetic interaction with arm inferred from genetic interaction with Axn inferred from genetic interaction with wg transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement "pygo, Pygo, CG11518, gam, BEST:LD21971, pNB5.2, anon-WO02077023.1, pypo, pyg, dPygo, Dm Pygo" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11518 11-Aug-17 DroID_v2017_08 "Drer\pygo1, Drer\pygo2" - "Cele\col-146, Cele\col-44, Cele\C02B10.5" Xtro\pygo1 "Mmus\Col8a1, Mmus\Pygo2, Mmus\Chtf8, Mmus\Pygo1" "Hsap\PYGO2, Hsap\CHTF8, Hsap\PYGO1" " larval stage , embryonic stage " organism

"visible,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,lethal,recessive,germline clone,maternal effect,decreased cell death,somatic clone,segment polarity phenotype,lethal - all die before end of embryonic stage,some die during embryonic stage,pair rule phenotype,increased cell death,cell growth defective,cell shape defective,neuroanatomy defective,partially lethal - majority die" "eye,dorsocentral bristle,scutellar bristle,adult cuticle,leg,sex comb,wing,denticle belt,cuticle,embryonic epidermis,somatic clone,wing margin,imaginal disc,eye photoreceptor cell,ectopic,ommatidium,photoreceptor cell,RP2 motor neuron,embryonic/first instar larval cuticle,rescuable maternal effect,embryo,maternal effect,wing margin bristle,cell non-autonomous,germline clone,distal,midgut constriction 2,denticle,wing disc,cone cell,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0002469 l(3)SG24 lethal (3) SG24 http://flybase.org/reports/FBgn0002469 - gene - - - l(3)SG24 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "eye-antennal disc,wing disc,metathoracic leg disc" FBgn0035918 Cdc6 Cdc6 http://flybase.org/reports/FBgn0035918 protein_coding_gene - cell division ; GO:0051301 | inferred from electronic annotation with InterPro:IPR016314 DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR016314 nucleus ; GO:0005634 | inferred from direct assay "Cdc6, DmCdc6, CG5971, cdc6, CDC6" "IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR015163:Cdc6, C-terminal, IPR016314:Cell division protein Cdc6/18, IPR011991:Winged helix-turn-helix DNA-binding domain" CG5971 11-Aug-17 DroID_v2017_08 "Drer\cdc6, Drer\orc1" "Scer\CDC6, Scer\SIR3, Scer\ORC1" "Cele\cdc-6, Cele\orc-1" "Xtro\orc1, Xtro\cdc6" "Mmus\Cdc6, Mmus\Orc1" "Hsap\ORC1, Hsap\CDC6" FBgn0030359 CG18130 - http://flybase.org/reports/FBgn0030359 protein_coding_gene - cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR017937 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG18130 "IPR012336:Thioredoxin-like fold, IPR017937:Thioredoxin, conserved site, IPR031827:Domain of unknown function DUF4746" CG18130 11-Aug-17 DroID_v2017_08 Drer\nme8 - - Xtro\nme9 "Mmus\Nme9, Mmus\Nme8" "Hsap\NME9, Hsap\NME8" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0034259 P32 P32 http://flybase.org/reports/FBgn0034259 protein_coding_gene histone binding ; GO:0042393 | inferred from direct assay "sperm chromatin decondensation ; GO:0035041 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay nucleosome assembly ; GO:0006334 | inferred from direct assay fertilization, exchange of chromosomal proteins ; GO:0035042 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype regulation of calcium-mediated signaling ; GO:0050848 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q07021 "CG6459, P32, dp32, CG 6459, p32, TAP, TAP/p32" IPR003428:Mitochondrial glycoprotein CG6459 11-Aug-17 DroID_v2017_08 Drer\c1qbp Scer\MAM33 Cele\cri-3 Xtro\c1qbp Mmus\C1qbp Hsap\C1QBP "paralytic,recessive,heat sensitive,neurophysiology defective,viable,fertile" FBgn0020270 mre11 meiotic recombination 11 http://flybase.org/reports/FBgn0020270 - protein_coding_gene "endonuclease activity ; GO:0004519 | inferred from electronic annotation with InterPro:IPR003701, InterPro:IPR007281 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR007281 3'-5' exonuclease activity ; GO:0008408 | inferred from electronic annotation with InterPro:IPR003701" "double-strand break repair ; GO:0006302 | inferred from electronic annotation with InterPro:IPR003701, InterPro:IPR007281 telomere maintenance ; GO:0000723 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype intra-S DNA damage checkpoint ; GO:0031573 | inferred from biological aspect of ancestor with PANTHER:PTN000015646" Mre11 complex ; GO:0030870 | inferred from electronic annotation with InterPro:IPR003701 "MRE11, Mre11, CG16928, mre11, 16928" "IPR003701:DNA double-strand break repair protein Mre11, IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR007281:Mre11, DNA-binding, IPR029052:Metallo-dependent phosphatase-like" CG16928 11-Aug-17 DroID_v2017_08 Drer\mre11a Scer\MRE11 Cele\mre-11 Xtro\mre11a Mmus\Mre11a Hsap\MRE11 "lethal - all die before end of pupal stage,some die during pupal stage,female sterile,male fertile,mitotic cell cycle defective,lethal,maternal effect,radiation sensitive,recessive,viable" "chromosome & neuroblast | third instar larval stage 2,mitosis & nuclear chromosome,chromosome, telomeric region" FBgn0027083 MetRS-m "Methionyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0027083 "FBgn0038215, FBgn0038216, FBgn0051322" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR009080, InterPro:IPR014758, InterPro:IPR015413 methionine-tRNA ligase activity ; GO:0004825 | traceable author statement methionine-tRNA ligase activity ; GO:0004825 | inferred from sequence or structural similarity with UniProtKB:Q96GW9" methionyl-tRNA aminoacylation ; GO:0006431 | traceable author statement methionyl-tRNA aminoacylation ; GO:0006431 | inferred from sequence or structural similarity with UniProtKB:Q96GW9 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q96GW9 mitochondrion ; GO:0005739 | traceable author statement "CG9612, MetRS, MRS, CG31322, CG8684, Aats-met, MetRS-m, Aats-met-m" "IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR014758:Methionyl-tRNA synthetase, IPR015413:Methionyl/Leucyl tRNA synthetase, IPR033911:Methioninyl-tRNA synthetase core domain" CG31322 11-Aug-17 DroID_v2017_08 Drer\mars2 Scer\MSM1 Cele\Y105E8A.20 Xtro\mars2 Mmus\Mars2 Hsap\MARS2 embryonic stage

ubiquitous "neurophysiology defective,somatic clone,conditional,neuroanatomy defective,short lived,flightless,partially lethal - majority die,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,lethal,lethal - all die before end of larval stage,some die during third instar larval stage,decreased cell size,cell autonomous" "mitochondrion,eye photoreceptor cell,conditional,retinal pigment cell,indirect flight muscle,imaginal disc,embryonic/larval brain,wing disc,somatic clone,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0004406 tam tamas http://flybase.org/reports/FBgn0004406 "FBgn0000476, FBgn0001960, FBgn0020604" protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001098, InterPro:IPR002297 DNA-directed DNA polymerase activity ; GO:0003887 | non-traceable author statement DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity 3'-5' exonuclease activity ; GO:0008408 | inferred from biological aspect of ancestor with PANTHER:PTN000030201 DNA-directed DNA polymerase activity ; GO:0003887 | inferred from direct assay DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity with UniProtKB:P54098" mitochondrial DNA replication ; GO:0006264 | inferred from mutant phenotype eclosion ; GO:0007562 | non-traceable author statement DNA-dependent DNA replication ; GO:0006261 | non-traceable author statement determination of adult lifespan ; GO:0008340 | non-traceable author statement DNA-dependent DNA replication ; GO:0006261 | inferred from direct assay axonal transport of mitochondrion ; GO:0019896 | inferred from mutant phenotype mitochondrial DNA replication ; GO:0006264 | traceable author statement DNA-dependent DNA replication ; GO:0006261 | inferred from sequence or structural similarity with UniProtKB:P54098 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P54098 gamma DNA polymerase complex ; GO:0005760 | inferred from direct assay gamma DNA polymerase complex ; GO:0005760 | inferred from sequence or structural similarity mitochondrion ; GO:0005739 | non-traceable author statement "pol gamma-alpha, AAC47658, mtDNA pol, l(2)34Dc, polgamma-alpha, MtPolA, anon-34Dc, BG:DS00941.6, polgamma, Polgamma, l(2)brS, DNApol-gamma125, DNApol-gamma, cDNA 2, 34Dc, br5, l(2)br5, l(2)br14, CG8987, tam, pol gamma, D-pol gamma-alpha, mtPolA, Tam, DmPOLgammaA, POLGalpha, Pol gamma, Polg" "IPR001098:DNA-directed DNA polymerase, family A, palm domain, IPR002297:DNA-directed DNA-polymerase, family A, mitochondria, IPR019760:DNA-directed DNA polymerase, family A, conserved site, IPR012337:Ribonuclease H-like domain" CG8987 11-Aug-17 DroID_v2017_08 Drer\polg Scer\MIP1 Cele\polg-1 Xtro\polg Mmus\Polg Hsap\POLG "lethal,recessive,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,visible,viable,poor,neuroanatomy defective,gravitaxis defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,short lived" "eye disc,photoreceptor cell,photoreceptor cell & axon,head bristle,scutum & macrochaeta,wing,wing vein,eye,adult thorax & macrochaeta,mitochondrion,adult cuticle,leg,macrochaeta,pupal cuticle,mesothoracic tergum,wing margin bristle,dopaminergic PPL1 neuron,dopaminergic PPL2ab neuron,dopaminergic PPL2c neuron,dopaminergic PPM1 neuron,dopaminergic PPM2 neuron,dopaminergic PPM3 neuron,dopaminergic PAL neuron,serotonergic neuron" FBgn0030323 CG2371 - http://flybase.org/reports/FBgn0030323 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG2443, CG2442, CG2371" IPR017920:COMM domain CG2371 11-Aug-17 DroID_v2017_08 Drer\commd10 - - "Xtro\commd4, Xtro\commd10" "Mmus\Commd10, Mmus\Commd4" "Hsap\COMMD10, Hsap\COMMD4" "viable,fertile,visible" trichogen cell FBgn0016934 smi61A smell impaired 61A http://flybase.org/reports/FBgn0016934 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi61A - - 11-Aug-17 DroID_v2017_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0003387 shb shortened bristles http://flybase.org/reports/FBgn0003387 - gene - - - shb - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male fertile,viable,male,reduced,visible" "wing,macrochaeta" FBgn0002770 mk murky http://flybase.org/reports/FBgn0002770 - gene - oogenesis ; GO:0048477 | traceable author statement - "fs(1)M7, mk" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage,viable,male,reduced,male fertile,visible,eye color defective,body color defective" "egg,pigment cell,adult thorax,trident" FBgn0037906 PGRP-LB Peptidoglycan recognition protein LB http://flybase.org/reports/FBgn0037906 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | traceable author statement N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | inferred from sequence or structural similarity with PGRP-SC1b N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VHB3 amidase activity ; GO:0004040 | non-traceable author statement innate immune response ; GO:0045087 | inferred from electronic annotation with InterPro:IPR017331 immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement peptidoglycan metabolic process ; GO:0000270 | non-traceable author statement negative regulation of peptidoglycan recognition protein signaling pathway ; GO:0061060 | inferred from direct assay innate immune response ; GO:0045087 | non-traceable author statement peptidoglycan catabolic process ; GO:0009253 | inferred from sequence or structural similarity with PGRP-SC1b defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG14704, PGRP-LB, pgrp-LB" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR017331:Peptidoglycan recognition protein, PGRP-S" CG14704 11-Aug-17 DroID_v2017_08 "Drer\pglyrp6, Drer\pglyrp2, Drer\pglyrp5" - - "Xtro\pglyrp1, Xtro\pglyrp1, Xtro\pglyrp2" "Mmus\Pglyrp2, Mmus\Pglyrp3, Mmus\Pglyrp1, Mmus\Pglyrp4" "Hsap\PGLYRP1, Hsap\PGLYRP2, Hsap\PGLYRP3, Hsap\PGLYRP4" "immune response defective,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,viable,fertile,short lived" FBgn0013548 l(2)dtl lethal-(2)-denticleless http://flybase.org/reports/FBgn0013548 FBgn0034895 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "DTL83, CG11295, l(2)dtl, L2DTL, Cdt2, cdt2" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG11295 11-Aug-17 DroID_v2017_08 Drer\dtl - Cele\cdt-2 "Xtro\katnb1, Xtro\dtl" Mmus\Dtl Hsap\DTL " embryonic stage , embryonic stage -- adult stage "

ubiquitous "male sterile,female fertile,lethal - all die during larval stage,male fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective" "denticle belt,embryonic/larval neuroblast,ganglion mother cell" DRSC04697 IK -3.132139065 -2.204922322 -1.341869696 -0.977035388 5.454702345 5.976318844 FBgn0000419 db dark body http://flybase.org/reports/FBgn0000419 - gene - - - db - - 11-Aug-17 DroID_v2017_08 - - - - - - "male fertile,viable,female,female semi-sterile,body color defective,lethal - all die before end of pupal stage,male,recessive,some die during pupal stage,lethal,visible" "adult cuticle,wing,cuticle" FBgn0003899 twg twisted genitals http://flybase.org/reports/FBgn0003899 - gene - - - twg - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,viable,male,reduced,male fertile" "eye,wing,wing vein,macrochaeta,genitalia,tergite" FBgn0004087 Dhfr Dihydrofolate reductase http://flybase.org/reports/FBgn0004087 - protein_coding_gene NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR012259 dihydrofolate reductase activity ; GO:0004146 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q26366 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001796, InterPro:IPR012259, InterPro:IPR017925 nucleotide biosynthetic process ; GO:0009165 | inferred from electronic annotation with InterPro:IPR001796, InterPro:IPR012259 glycine biosynthetic process ; GO:0006545 | inferred from electronic annotation with InterPro:IPR001796, InterPro:IPR012259" - "DHFR, dhfr, CG14887, Dhfr" "IPR001796:Dihydrofolate reductase domain, IPR012259:Dihydrofolate reductase, IPR024072:Dihydrofolate reductase-like domain, IPR017925:Dihydrofolate reductase conserved site" CG14887 11-Aug-17 DroID_v2017_08 "Drer\zgc:153031, Drer\dhfr, Drer\ovca2" "Scer\DFR1, Scer\FSH2, Scer\FSH3, Scer\FSH1" "Cele\dhfr-1, Cele\C25G4.2" "Xtro\ovca2, Xtro\dhfr" "Mmus\Dhfr, Mmus\Ovca2" "Hsap\DHFR, Hsap\OVCA2, Hsap\DHFR2" adult stage viable FBgn0002162 l(2)Sp6b lethal (2) Sp6b http://flybase.org/reports/FBgn0002162 - gene - - - l(2)Sp6b - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0069311 X-210-22 X-210-22 http://flybase.org/reports/FBgn0069311 gene molecular_function ; GO:0003674 | no biological data available nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-210-22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect" FBgn0032799 CG10166 - http://flybase.org/reports/FBgn0032799 protein_coding_gene dolichyl-phosphate beta-D-mannosyltransferase activity ; GO:0004582 | inferred from sequence or structural similarity with SGD:S000006387 protein glycosylation ; GO:0006486 | inferred from sequence or structural similarity with SGD:S000006387 - "CG10166, Dol-P-ManTase, dDPM" "IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG10166 11-Aug-17 DroID_v2017_08 Drer\dpm1 "Scer\ALG5, Scer\DPM1" "Cele\H43I07.3, Cele\dpm-1" Xtro\dpm1 "Mmus\Dpm1, Mmus\Alg5, Mmus\Ugcg" "Hsap\DPM1, Hsap\UGCG" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0017578 Max Max http://flybase.org/reports/FBgn0017578 - protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Mnt transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay" nucleus ; GO:0005634 | inferred by curator from GO:0006355 "Max, dMax, max, dmax, CG9648, bHLHd9, MAX" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG9648 11-Aug-17 DroID_v2017_08 "Drer\mxd4, Drer\max" "Scer\RTG3, Scer\HMS1" "Cele\mxl-2, Cele\mxl-3, Cele\mxl-1" Xtro\max "Mmus\Max, Mmus\Mxd4, Mmus\Mnt" "Hsap\MAX, Hsap\MNT, Hsap\MXD4" " embryonic stage , embryonic stage -- adult stage " " mesoderm | presumptive

, embryonic central nervous system

, posterior midgut proper primordium

, anterior midgut proper primordium

" "viable,visible,lethal,recessive,somatic clone,small body,developmental rate defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,chaeta,somatic clone,mouth hooks,anterior pupal spiracle,scutellar bristle,anterior scutellar bristle,posterior scutellar bristle,wing" FBgn0014396 tim timeless http://flybase.org/reports/FBgn0014396 FBgn0015535 protein_coding_gene protein heterodimerization activity ; GO:0046982 | traceable author statement protein heterodimerization activity ; GO:0046982 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with per protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Clk protein binding ; GO:0005515 | inferred from physical interaction with cry transcription factor binding ; GO:0008134 | inferred from physical interaction with Clk "negative phototaxis ; GO:0046957 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype cellular response to light stimulus ; GO:0071482 | inferred from mutant phenotype protein import into nucleus ; GO:0006606 | non-traceable author statement regulation of phagocytosis ; GO:0050764 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement circadian behavior ; GO:0048512 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | traceable author statement copulation ; GO:0007620 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | non-traceable author statement locomotor rhythm ; GO:0045475 | inferred from genetic interaction with jet entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | traceable author statement circadian rhythm ; GO:0007623 | non-traceable author statement eclosion rhythm ; GO:0008062 | traceable author statement sleep ; GO:0030431 | non-traceable author statement circadian temperature homeostasis ; GO:0060086 | inferred from mutant phenotype rhythmic behavior ; GO:0007622 | traceable author statement photoperiodism ; GO:0009648 | inferred from mutant phenotype regulation of circadian sleep/wake cycle ; GO:0042749 | inferred from mutant phenotype positive regulation of phagocytosis ; GO:0050766 | inferred from mutant phenotype entrainment of circadian clock ; GO:0009649 | traceable author statement regulation of protein import into nucleus ; GO:0042306 | traceable author statement mating behavior ; GO:0007617 | inferred from mutant phenotype circadian regulation of heart rate ; GO:0003053 | inferred from mutant phenotype eclosion rhythm ; GO:0008062 | non-traceable author statement negative regulation of transcription regulatory region DNA binding ; GO:2000678 | inferred from direct assay" cytoplasm ; GO:0005737 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | non-traceable author statement protein complex ; GO:0043234 | inferred from physical interaction with cry "tim, TIM, dTim, dtim, tim1, dTIM, Ritsu, rit, CG3234, Tim, mel_tim" IPR006906:Timeless protein CG3234 11-Aug-17 DroID_v2017_08 Drer\timeless Scer\TOF1 Cele\tim-1 Xtro\timeless Mmus\Timeless Hsap\TIMELESS " adult stage , adult stage" " ventral adult lateral neuron

, adult brain | restricted

, photoreceptor cell

, adult lateral neuron

, head

, adult head

, dorsal adult lateral neuron

" " adult stage , larval stage | third instar " " adult head

, glial cell &&of medulla | restricted

, glial cell &&of lamina | restricted

, larval lateral neuron

, neuron &&of protocerebrum

, photoreceptor cell

, neuron &&of protocerebrum | restricted

" "locomotor rhythm defective,semidominant,viable,neuroanatomy defective,circadian rhythm defective,fertile,wild-type,recessive,mating defective,semi-sterile,mating rhythm defective,photoperiod response variant,conditional,semi-fertile,sleep defective,behavior defective,visual behavior defective,stress response defective,circadian behavior defective,dominant,eclosion rhythm defective" "indirect flight muscle motor neuron MN5,posterior adult hindgut,Malpighian tubule" FBgn0052296 Mrtf Myocardin-related transcription factor http://flybase.org/reports/FBgn0052296 protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with bs activating transcription factor binding ; GO:0033613 | inferred from physical interaction with bs RNA polymerase II transcription coactivator activity ; GO:0001105 | inferred from direct assay" regulation of cell division ; GO:0051302 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay mesodermal cell migration ; GO:0008078 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DMRTF, mal-d, CG32296, CG12188, CG14951, Mrtf, Mal-D, MAL-D, MRTF, dMrtf, dMRTF, mal" "IPR003034:SAP domain, IPR004018:RPEL repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG32296 11-Aug-17 DroID_v2017_08 "Drer\mkl1a, Drer\mkl2a, Drer\mkl2b, Drer\mkl1b, Drer\si:dkeyp-69b9.3, Drer\myocd" - Cele\pqn-62 "Xtro\emsy, Xtro\mkl2, Xtro\mkl1, Xtro\myocd" "Mmus\Mkl1, Mmus\Myocd, Mmus\Mkl2" "Hsap\MKL2, Hsap\MKL1, Hsap\MYOCD" "visible,recessive,viable,fertile,lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,female sterile,neuroanatomy defective,size defective" "presumptive embryonic/larval tracheal system,chaeta,dorsal branch primordium,ganglionic branch primordium,embryonic/larval dorsal anastomosis,dorsal trunk primordium,border follicle cell,somatic clone,follicle cell & actin filament | somatic clone,nurse cell ring canal,cell autonomous,border follicle cell & actin filament,ellipsoid body,mesoderm,cardioblast,cardiogenic mesoderm,embryonic somatic muscle,dorsal,wing,wing cell,embryonic dorsal vessel,follicle cell & actin filament | ectopicslbo.2.6,wing vein" DRSC08410 E 0.576605916 0.145201744 1.382253748 1.757396492 1.134213506 1.179685582 FBgn0030664 CG8119 - http://flybase.org/reports/FBgn0030664 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - - CG8119 "IPR004210:BESS motif, IPR006578:MADF domain" CG8119 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-207i20.3, Drer\LOC100330838, Drer\zgc:152938" - "Cele\madf-2, Cele\madf-5, Cele\madf-4, Cele\madf-3, Cele\madf-10, Cele\madf-8, Cele\madf-9" - - - viable FBgn0001768 l(1)M38 lethal (1) M38 http://flybase.org/reports/FBgn0001768 - gene - - - l(1)M38 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0030993 Mec2 Mec2 http://flybase.org/reports/FBgn0030993 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with sns nephrocyte filtration ; GO:0097206 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001972 nephrocyte diaphragm ; GO:0005917 | inferred by curator from GO:0005515 "Mec2, DMec2, CG7635" "IPR001107:Band 7 domain, IPR001972:Stomatin family" CG7635 11-Aug-17 DroID_v2017_08 "Drer\stoml2, Drer\zgc:112408, Drer\stoml3a, Drer\stoml3b, Drer\stom, Drer\stoml1, Drer\nphs2" - "Cele\sto-2, Cele\unc-1, Cele\sto-3, Cele\sto-4, Cele\stl-1, Cele\sto-5, Cele\sto-1, Cele\unc-24, Cele\sto-6, Cele\mec-2" "Xtro\stoml3, Xtro\stoml1" "Mmus\Stoml3, Mmus\Nphs2, Mmus\Stom, Mmus\Stoml2, Mmus\Stoml1" "Hsap\STOML2, Hsap\NPHS2, Hsap\STOML3, Hsap\STOM, Hsap\STOML1" "viable,fertile" "embryonic/larval pericardial cell,nephrocyte diaphragmDot.PK" FBgn0002560 Lot-1 Lot 1 http://flybase.org/reports/FBgn0002560 - gene - - - "Lot1, Lot-94, Lot, Lo-94, Lot-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "chemosensitive behavior defective,semidominant,recessive" FBgn0003747 Gr5a Gustatory receptor 5a http://flybase.org/reports/FBgn0003747 "FBgn0029787, FBgn0041213" protein_coding_gene taste receptor activity ; GO:0008527 | inferred from mutant phenotype taste receptor activity ; GO:0008527 | non-traceable author statement taste receptor activity ; GO:0008527 | traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of sweet taste ; GO:0001582 | inferred from mutant phenotype sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from direct assay response to trehalose ; GO:0010353 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | inferred from direct assay proboscis extension reflex ; GO:0007637 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009318 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr5a, CG15779, tre, GrLU7, Gr5A1, LU.7, GRLU.7, Tre, Gr5, han, Dmel5a, GR5A, GR5a" IPR009318:Gustatory receptor CG15779 11-Aug-17 DroID_v2017_08 - - - - - - adult stage gustatory sensory organ

"taste perception defective,neurophysiology defective,proboscis extension reflex defective,recessive,feeding behavior defective,semidominant,viable" "large labellar taste bristle,labellar taste bristle" FBgn0085446 CG34417 - http://flybase.org/reports/FBgn0085446 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity mesoderm development ; GO:0007498 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay "CG34417, CG3950, BcDNA:GH23906, CG3960" "IPR001715:Calponin homology domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR022189:Smoothelin" CG34417 11-Aug-17 DroID_v2017_08 "Drer\smtna, Drer\smtnb, Drer\smtnl1, Drer\poldip2, Drer\si:ch211-195o20.7, Drer\specc1la, Drer\specc1lb" - Cele\T15B12.1 "Xtro\smtn, Xtro\specc1l" "Mmus\Specc1, Mmus\Pclo, Mmus\Smtn, Mmus\Srrm3, Mmus\Srrm2, Mmus\Dspp, Mmus\Smtnl1, Mmus\Specc1l, Mmus\Smtnl2" "Hsap\SMTNL1, Hsap\SMTN, Hsap\SMTNL2, Hsap\SRRM3, Hsap\SPECC1L, Hsap\MUC4, Hsap\PCLO, Hsap\SRRM2, Hsap\SPECC1, Hsap\DSPP" "viable,fertile" FBgn0003261 Rm62 Rm62 http://flybase.org/reports/FBgn0003261 "FBgn0010736, FBgn0011038, FBgn0011355, FBgn0011356, FBgn0011496, FBgn0011645" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 protein binding ; GO:0005515 | inferred from physical interaction with Fmr1 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218" nucleus ; GO:0005634 | inferred by curator from GO:0000381 polytene chromosome puff ; GO:0005703 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "Rm62, CG10279, Dmp68, p68, Lip, RM62, DmRH8, 4136, l(3)s5196, l(3)rG338, l(3)j3D5, l(3)j3D2, l(3)01086, rm62, dmP68" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10279 11-Aug-17 DroID_v2017_08 "Drer\clk4a, Drer\clk2a, Drer\clk4b, Drer\ddx21, Drer\ddx5, Drer\tdrd12, Drer\ddx59, Drer\LOC556764, Drer\clk2b" "Scer\DBP3, Scer\DBP2" "Cele\madd-3, Cele\ddx-17, Cele\Y54G11A.3" "Xtro\ddx21, Xtro\gpr149, Xtro\ddx59, Xtro\clk1, Xtro\ddx5, Xtro\clk2, Xtro\ddx17, Xtro\clk3" "Mmus\Clk2, Mmus\Clk4, Mmus\Ddx50, Mmus\Gpr149, Mmus\Clk3, Mmus\Ddx3x, Mmus\Clk1, Mmus\Ddx17, Mmus\Ddx5, Mmus\Ddx59, Mmus\Tdrd12, Mmus\Ddx21" "Hsap\CLK2, Hsap\GPR149, Hsap\CLK3, Hsap\DDX5, Hsap\CLK1, Hsap\CLK4, Hsap\DDX50, Hsap\DDX43, Hsap\DDX17, Hsap\TDRD12, Hsap\DDX59, Hsap\DDX21" " adult stage , larval stage , embryonic stage " "lethal,recessive,viable,sterile,visible,dominant,developmental rate defective,male sterile,female sterile,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "class IV dendritic arborizing neuron,somatic clone,pigment cell,nurse cell & nuclear chromosome,egg chamber,dorsocentral bristle,scutellar bristle,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC12365 E -1.20788071 0.085471981 -2.041721811 -0.257850883 1.258657422 -0.131489913 FBgn0024248 chico chico http://flybase.org/reports/FBgn0024248 "FBgn0013449, FBgn0014169, FBgn0028483, FBgn0043507, FBgn0043508" protein_coding_gene insulin receptor binding ; GO:0005158 | inferred from physical interaction with UniProtKB:P09208 insulin-like growth factor receptor binding ; GO:0005159 | inferred from sequence or structural similarity with HGNC:6125 inferred from sequence or structural similarity with HGNC:6126 inferred from genetic interaction with InR phosphatidylinositol 3-kinase binding ; GO:0043548 | inferred from biological aspect of ancestor with PANTHER:PTN000064809 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with UniProtKB:P35568 insulin-like growth factor receptor binding ; GO:0005159 | inferred from sequence or structural similarity with UniProtKB:P35568 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000064809 SH2 domain binding ; GO:0042169 | inferred from sequence or structural similarity with UniProtKB:P35570 phosphatidylinositol 3-kinase binding ; GO:0043548 | inferred from sequence or structural similarity with UniProtKB:P35570 "positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype primary spermatocyte growth ; GO:0007285 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype long-term synaptic potentiation ; GO:0060291 | inferred from mutant phenotype regulation of activin receptor signaling pathway ; GO:0032925 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | traceable author statement regulation of cell size ; GO:0008361 | traceable author statement cell morphogenesis ; GO:0000902 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | traceable author statement multicellular organism growth ; GO:0035264 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from physical interaction with UniProtKB:P09208 response to anoxia ; GO:0034059 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement regulation of cell size ; GO:0008361 | non-traceable author statement aging ; GO:0007568 | inferred from mutant phenotype positive regulation of organ growth ; GO:0046622 | traceable author statement regulation of lipid metabolic process ; GO:0019216 | inferred from biological aspect of ancestor with PANTHER:PTN000064809 regulation of organ growth ; GO:0046620 | inferred from mutant phenotype insulin-like growth factor receptor signaling pathway ; GO:0048009 | inferred from sequence or structural similarity with UniProtKB:P35568 regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype regulation of organ growth ; GO:0046620 | non-traceable author statement vitellogenesis ; GO:0007296 | inferred from mutant phenotype multicellular organism aging ; GO:0010259 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | non-traceable author statement positive regulation of immune response ; GO:0050778 | inferred from mutant phenotype lipid metabolic process ; GO:0006629 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype response to starvation ; GO:0042594 | traceable author statement cellular metabolic process ; GO:0044237 | traceable author statement positive regulation of cell size ; GO:0045793 | non-traceable author statement olfactory learning ; GO:0008355 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | non-traceable author statement male germ-line stem cell asymmetric division ; GO:0048133 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | traceable author statement insulin receptor signaling pathway ; GO:0008286 | inferred from genetic interaction with Pi3K92E inferred from genetic interaction with InR positive regulation of organ growth ; GO:0046622 | non-traceable author statement regulation of multicellular organism growth ; GO:0040014 | traceable author statement" plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000064809 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P35569 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P35569 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000064809 intracellular membrane-bounded organelle ; GO:0043231 | inferred from sequence or structural similarity with UniProtKB:P35569 "dIRS, CHICO, BcDNA.GH11263, IRS, fs(2)4, anon-WO0078940.1, fs(2)ry4, chic, CG5686, BcDNA:GH11263, anon-WO0078940.4, chico, IRS/chico, Chico" "IPR001849:Pleckstrin homology domain, IPR002404:IRS-type PTB domain, IPR011993:PH domain-like" CG5686 11-Aug-17 DroID_v2017_08 "Drer\irs2a, Drer\irs2b, Drer\irs4a, Drer\si:ch73-335l21.1, Drer\irs1, Drer\si:ch211-284e13.4" - - "Xtro\irs1, Xtro\irs4, Xtro\irs2" "Mmus\Irs3, Mmus\Irs1, Mmus\Irs2, Mmus\Irs4" "Hsap\IRS2, Hsap\IRS1, Hsap\IRS4" "small body,decreased cell number,decreased cell size,visible,partially lethal - majority die,learning defective,recessive,viable,female sterile,long lived,male semi-sterile,dominant,developmental rate defective,partially lethal - majority live,neurophysiology defective,size defective,stress response defective,female limited,neuroanatomy defective,starvation stress response defective,somatic clone,radiation sensitive,wild-type,reduced" "adult,eye,ommatidium,wing,ovary,follicle cell,egg chamber,adult heart,cell autonomous,somatic clone,head capsule,maxillary palpus,male,genital arch,larva,nurse cell,Kenyon cell,adult mushroom body,adult brain,adult gut,wing disc,embryonic/larval dorsal trunk,embryonic/larval transverse connective,larval salivary gland & nucleus,ellipsoid body,synapse,male germline stem cell,polar primary spermatocyte,primary spermatocyte" DRSC03531 I -0.081804826 2.60407301 -1.149392713 -0.693893623 0.007064413 0.855330773 FBgn0038206 twf twinfilin http://flybase.org/reports/FBgn0038206 protein_coding_gene actin binding ; GO:0003779 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype actin filament depolymerization ; GO:0030042 | inferred from direct assay regulation of lamellipodium assembly ; GO:0010591 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype negative regulation of actin filament polymerization ; GO:0030837 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG3172, A6, twf, Twf" "IPR002108:Actin-depolymerising factor homology domain, IPR028458:Twinfilin, IPR029006:ADF-H/Gelsolin-like domain" CG3172 11-Aug-17 DroID_v2017_08 "Drer\twf1b, Drer\twf1a, Drer\twf2b, Drer\wdr82, Drer\twf2, Drer\tlr9, Drer\LOC103909995" Scer\TWF1 "Cele\swd-2.2, Cele\F38E9.5, Cele\swd-2.1" "Xtro\twf2, Xtro\twf1, Xtro\tlr9" "Mmus\Twf2, Mmus\Wdr82, Mmus\Twf1, Mmus\Tlr9" "Hsap\TWF2, Hsap\TWF1, Hsap\TLR9, Hsap\WDR82" " larval stage | third instar , pupal stage , larval stage | first instar , larval stage | second instar , embryonic stage , adult stage | female , adult stage | male " " pupal stage | 32hr , embryonic stage , oogenesis stage , larval stage " " microchaeta

,

ubiquitous , border follicle cell

, macrochaeta

, ovary

" "viable,small body,hypoactive,flightless,developmental rate defective,visible,neuroanatomy defective,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage" "macrochaeta,ommatidium,interommatidial bristle,microchaeta,trichome,actin filament[-],chaeta,adult mushroom body,mushroom body beta-lobe,mushroom body alpha-lobe,border follicle cell,heat sensitive,trichogen cell,supernumerary,somatic clone,NMJ bouton" FBgn0065128 l(3)SH137 lethal (3) SH137 http://flybase.org/reports/FBgn0065128 gene - - - "l(3)SH137, l(2)SH3 137" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001671 l(1)EN8 lethal (1) from Eugene Nonautonomous 8 http://flybase.org/reports/FBgn0001671 - gene - - - l(1)EN8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive,lethal - all die before end of larval stage,some die during larval stage" "egg chamber,germline clone,maternal effect,fat body,Malpighian tubule,embryonic/larval salivary gland,adult cuticle" FBgn0039450 CG5484 - http://flybase.org/reports/FBgn0039450 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000363019 cell morphogenesis ; GO:0000902 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000363019 endoplasmic reticulum-Golgi intermediate compartment ; GO:0005793 | inferred from biological aspect of ancestor with PANTHER:PTN000363019 ER to Golgi transport vesicle ; GO:0030134 | inferred from biological aspect of ancestor with PANTHER:PTN000363019 integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000363019 "anon-WO0118547.366, CG5484, COP" IPR005578:Yif1 family CG5484 11-Aug-17 DroID_v2017_08 "Drer\yif1b, Drer\yif1a" Scer\YIF1 Cele\yif-1 Xtro\yif1b "Mmus\Yif1a, Mmus\Yif1b" "Hsap\YIF1A, Hsap\YIF1B" lethal FBgn0002526 LanA Laminin A http://flybase.org/reports/FBgn0002526 FBgn0015948 protein_coding_gene receptor binding ; GO:0005102 | inferred from electronic annotation with InterPro:IPR009254 "regulation of cell migration ; GO:0030334 | inferred from electronic annotation with InterPro:IPR009254 regulation of cell adhesion ; GO:0030155 | inferred from electronic annotation with InterPro:IPR009254 regulation of embryonic development ; GO:0045995 | inferred from electronic annotation with InterPro:IPR009254 startle response ; GO:0001964 | inferred from mutant phenotype dorsal trunk growth, open tracheal system ; GO:0035001 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype substrate adhesion-dependent cell spreading ; GO:0034446 | inferred from direct assay mesoderm development ; GO:0007498 | inferred from expression pattern locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" presynaptic periactive zone ; GO:0036062 | inferred from direct assay basement membrane ; GO:0005604 | inferred from sequence or structural similarity basement membrane ; GO:0005604 | inferred from direct assay basal lamina ; GO:0005605 | inferred from direct assay "lanA, laminin alpha3/5, lamA, CG10236, CT28769, LM-A/alpha1, alpha3/5, Lam-A, LamA, hdln, LanA, Lan, Lam, alpha[[3,5]], FBgn0002526, FBtr0077014" "IPR000034:Laminin IV, IPR001791:Laminin G domain, IPR002049:Laminin EGF domain, IPR008211:Laminin, N-terminal, IPR009254:Laminin alpha, domain I, IPR010307:Laminin domain II, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR008979:Galactose-binding domain-like, IPR000742:EGF-like domain, IPR011641:Tyrosine-protein kinase ephrin type A/B receptor-like" CG10236 11-Aug-17 DroID_v2017_08 "Drer\lama2, Drer\lamc1, Drer\si:ch211-241e1.3, Drer\lamc3, Drer\lama1, Drer\atrn, Drer\atrnl1a, Drer\agrn, Drer\ush2a, Drer\lama5, Drer\lama3, Drer\atrnl1b, Drer\lama4" "Scer\ZIP1, Scer\SPC110" "Cele\lam-3, Cele\lam-2, Cele\epi-1" "Xtro\lama3, Xtro\lama5, Xtro\lamc1, Xtro\lama4" "Mmus\Lama2, Mmus\Lama3, Mmus\Lamc2, Mmus\Agrn, Mmus\Atrnl1, Mmus\Lamc3, Mmus\Lama1, Mmus\Atrn, Mmus\Lama5, Mmus\Lama4, Mmus\Ush2a, Mmus\Lamc1, Mmus\Ntng1" "Hsap\LAMC1, Hsap\LAMC3, Hsap\AGRN, Hsap\ATRN, Hsap\LAMA2, Hsap\LAMA1, Hsap\USH2A, Hsap\LAMA4, Hsap\NTNG1, Hsap\LAMA3, Hsap\LAMC2, Hsap\ATRNL1, Hsap\LAMA5" " embryonic stage , embryonic stage | stage >12 , embryonic stage | late , embryonic stage | stage 11-12 " " somatic mesoderm

, interface glial cell

, glial cell | lateral

, embryonic brain

, hemocyte

, head mesoderm

, visceral mesoderm

, embryonic/larval fat body

, ventral nerve cord

, sense organ

, embryonic/larval midgut

, ectoderm

, ventral midline

" " embryonic stage , embryonic stage | stage 13-15 , embryonic stage | 10-13 hr " " ventral nerve cord

, neuropil associated CNS glial cell

, intersegmental nerve

, embryonic midgut

, embryonic brain

, epidermis

, embryonic/larval digestive system

, myoblast &&of larval muscle system

, embryonic spiracle

, segmental nerve

, hemocyte

, larval muscle system

, glial cell

, embryonic/larval fat body

" "lethal,behavior defective,recessive,viable,neuroanatomy defective,immune response defective,meiotic cell cycle defective,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,eye photoreceptor cell & axon,embryonic/larval optic stalk,optic nerve,glial cell,neuromuscular junction | third instar larval stageC57,macrochaeta,anterior fascicle & synapse,intersegmental nerve,embryonic/larval somatic muscle,embryonic/larval pericardial cell,abdominal 1 ventral oblique muscle 4,abdominal 2 ventral oblique muscle 4,abdominal 3 ventral oblique muscle 4,abdominal 4 ventral oblique muscle 4,abdominal 5 ventral oblique muscle 4,abdominal 6 ventral oblique muscle 4,abdominal 7 ventral oblique muscle 4,abdominal 1 ventral oblique muscle 5,abdominal 2 ventral oblique muscle 5,abdominal 3 ventral oblique muscle 5,abdominal 4 ventral oblique muscle 5,abdominal 5 ventral oblique muscle 5,abdominal 6 ventral oblique muscle 5,abdominal 7 ventral oblique muscle 5,abdominal 2 ventral oblique muscle 6,abdominal 3 ventral oblique muscle 6,abdominal 4 ventral oblique muscle 6,abdominal 5 ventral oblique muscle 6,abdominal 6 ventral oblique muscle 6,abdominal 7 ventral oblique muscle 6,abdominal 1 ventral acute muscle 3,abdominal 2 ventral acute muscle 3,abdominal 3 ventral acute muscle 3,abdominal 4 ventral acute muscle 3,abdominal 5 ventral acute muscle 3,abdominal 6 ventral acute muscle 3,abdominal 7 ventral acute muscle 3,embryonic/larval midgut & endoderm,fascicle,embryo,egg chamber,germline clone,oocyte nucleus,cell non-autonomous,somatic clone,muscle attachment site & basal lamina,bouton & neuromuscular junction & embryo,amnioserosa,dorsal superficial trachea,extracellular matrix,neuromuscular junction | third instar larval stage, with LanAGD6022, C57,embryonic/larval proventriculus,embryonic/larval midgut,embryonic head,ocellar nerve & axon,eye,leg,wing,antenna,ocellus,postvertical bristle,ocellar bristle,ommatidial precursor cluster,cone cell,eye photoreceptor cell,ocellar nerve,embryonic/larval dorsal vessel,germline cell,neuromuscular junction | third instar larval stage, with LanA9-32, C57" FBgn0037363 Atg17 Autophagy-related 17 http://flybase.org/reports/FBgn0037363 protein_coding_gene protein complex scaffold ; GO:0032947 | inferred from biological aspect of ancestor with PANTHER:PTN000996416 protein kinase regulator activity ; GO:0019887 | inferred from sequence or structural similarity with SGD:S000004415 protein kinase binding ; GO:0019901 | inferred from biological aspect of ancestor with PANTHER:PTN000996416 autophagy ; GO:0006914 | inferred from mutant phenotype inferred from genetic interaction with Atg1 cellular response to nitrogen starvation ; GO:0006995 | inferred from biological aspect of ancestor with PANTHER:PTN000996416 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype positive regulation of protein phosphorylation ; GO:0001934 | inferred from mutant phenotype pexophagy ; GO:0030242 | inferred from biological aspect of ancestor with PANTHER:PTN000996416 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype macroautophagy ; GO:0016236 | inferred from mutant phenotype reticulophagy ; GO:0061709 | inferred from biological aspect of ancestor with PANTHER:PTN000996416 activation of protein kinase activity ; GO:0032147 | inferred from sequence or structural similarity with SGD:S000004415 salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype glycophagy ; GO:0061723 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000996416 autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000996416 pre-autophagosomal structure ; GO:0000407 | inferred from direct assay pre-autophagosomal structure membrane ; GO:0034045 | inferred from biological aspect of ancestor with PANTHER:PTN000996416 ATG1/ULK1 kinase complex ; GO:1990316 | inferred from direct assay "Atg17, CG1347, RB1CC1, FIP200, Fip200, fip200, dAtg17" "IPR019460:Autophagy-related protein 11, IPR015943:WD40/YVTN repeat-like-containing domain" CG1347 11-Aug-17 DroID_v2017_08 Drer\rb1cc1 Scer\ATG11 Cele\epg-7 - Mmus\Rb1cc1 Hsap\RB1CC1 "viable,lethal,heat sensitive,locomotor behavior defective,flightless,visible,neuroanatomy defective,short lived,developmental rate defective,RU486 conditional,majority die during pharate adult stage,uncoordinated,starvation stress response defective,lethal - all die during pharate adult stage" "wing,autophagic vacuole,optic lobe,major mitochondrial derivativenos.PG, nos.UTR.THsimVP16, otu.THsimVP16,autophagic vacuole | third instar larval stage,embryonic/larval fat body,embryonic/larval salivary gland" FBgn0035281 Cpr62Bc Cuticular protein 62Bc http://flybase.org/reports/FBgn0035281 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr62Bc, CG1919, DmelCpr62Bc" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG1919 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - viable FBgn0000748 fs(1)A331 female sterile (1) A331 http://flybase.org/reports/FBgn0000748 - gene - - - fs(1)A331 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,non-rescuable maternal effect" FBgn0031005 Hs3st-B Heparan sulfate 3-O sulfotransferase-B http://flybase.org/reports/FBgn0031005 protein_coding_gene [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity ; GO:0008467 | inferred from sequence or structural similarity with UniProtKB:O14792 inferred from direct assay chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype lysosome organization ; GO:0007040 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype endosome organization ; GO:0007032 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype regulation of endosome size ; GO:0051036 | inferred from mutant phenotype - "Hs3st-B, CG7890, dHs3st-B, dHS3OSTB" "IPR000863:Sulfotransferase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7890 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-121b10.7, Drer\hs3st3b1a, Drer\hs3st4, Drer\hs3st3b1b, Drer\hs3st2, Drer\hs3st1l1, Drer\si:ch211-216b21.2, Drer\hs3st1, Drer\hs3st3l, Drer\hs3st1l2" - "Cele\hst-3.2, Cele\hst-3.1" "Xtro\hs3st1, Xtro\hs3st2, Xtro\hs3st5, Xtro\hs3st6, Xtro\LOC100125092" "Mmus\Hs3st4, Mmus\Hs3st1, Mmus\Hs3st6, Mmus\Hs3st5, Mmus\Hs3st2, Mmus\Hs3st3b1, Mmus\Hs3st3a1" "Hsap\HS3ST2, Hsap\HS3ST3B1, Hsap\HS3ST1, Hsap\HS3ST3A1, Hsap\HS3ST6, Hsap\HS3ST4, Hsap\HS3ST5" "visible,lethal" "eye,ommatidium,interommatidial bristle,mesothoracic tergum,macrochaeta,supernumerary,wing,anterior crossvein,wing vein L3,campaniform sensillum of anterior crossvein,sensillum campaniformium of dorsal radius,wing margin,sternopleural bristle,leg sensillum,tarsal segment,endosomedpp.blk1,lysosomedpp.blk1,anterior scutellar bristle,posterior scutellar bristle" FBgn0039802 dj-1beta dj-1beta http://flybase.org/reports/FBgn0039802 protein_coding_gene - "mitochondrial ATP synthesis coupled electron transport ; GO:0042775 | inferred from genetic interaction with DJ-1α response to oxidative stress ; GO:0006979 | inferred from mutant phenotype protein deglycosylation ; GO:0006517 | NOT inferred from direct assay methylglyoxal metabolic process ; GO:0009438 | NOT inferred from direct assay response to oxidative stress ; GO:0006979 | inferred from direct assay negative regulation of developmental growth ; GO:0048640 | inferred from mutant phenotype cellular response to hydrogen peroxide ; GO:0070301 | inferred from mutant phenotype regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from mutant phenotype protein deglycation, methylglyoxal removal ; GO:0036530 | NOT inferred from direct assay adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype" - "DJ-1beta, DJ-1B, CG1349, dj-1beta, DJ-1, DJ-1b, dj1-beta" "IPR002818:DJ-1/PfpI, IPR006287:Protein DJ-1, IPR029062:Class I glutamine amidotransferase-like" CG1349 11-Aug-17 DroID_v2017_08 "Drer\pddc1, Drer\park7" - "Cele\djr-1.1, Cele\djr-1.2" Xtro\park7 "Mmus\Park7, Mmus\Pddc1" "Hsap\PARK7, Hsap\PDDC1" "stress response defective,short lived,locomotor behavior defective,viable,fertile,chemical sensitive,chemical resistant,long lived,recessive,oxidative stress response defective,radiation sensitive" "dopaminergic neuron,mitochondrion,dorso-lateral dopaminergic neuron,embryonic/larval brain" FBgn0010292 bys by S6 http://flybase.org/reports/FBgn0010292 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG1430, bys" IPR007955:Bystin CG1430 11-Aug-17 DroID_v2017_08 Drer\bysl Scer\ENP1 Cele\byn-1 Xtro\bysl Mmus\Bysl Hsap\BYSL "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0070055 2L-144-32 2L-144-32 http://flybase.org/reports/FBgn0070055 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 2L-144-32 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" FBgn0002736 mago mago nashi http://flybase.org/reports/FBgn0002736 FBgn0002095 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P82804 "pole plasm assembly ; GO:0007315 | traceable author statement epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | non-traceable author statement microtubule cytoskeleton organization ; GO:0000226 | traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D RNA splicing ; GO:0008380 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype maintenance of pole plasm mRNA location ; GO:0046594 | traceable author statement oogenesis ; GO:0048477 | traceable author statement pole plasm assembly ; GO:0007315 | non-traceable author statement oocyte microtubule cytoskeleton organization ; GO:0016325 | traceable author statement regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype inferred from physical interaction with tsu mRNA export from nucleus ; GO:0006406 | non-traceable author statement negative regulation of transposition, DNA-mediated ; GO:0000335 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay pole plasm ; GO:0045495 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay exon-exon junction complex ; GO:0035145 | inferred from physical interaction with tsu precatalytic spliceosome ; GO:0071011 | inferred from direct assay "Mago, MAGOH, Magoh, MGN, Dm MGN, DmMago, mgn, l(2)57Ca, CG9401, mago, MAGO" IPR004023:Mago nashi protein CG9401 11-Aug-17 DroID_v2017_08 Drer\magoh - Cele\mag-1 Xtro\magoh "Mmus\Magohb, Mmus\Magoh" "Hsap\MAGOH, Hsap\MAGOHB" " embryonic stage -- adult stage , embryonic stage | early , adult stage && oogenesis stage " "

ubiquitous , oocyte

, nurse cell

" "lethal,recessive,wild-type,viable,lethal - all die before end of embryonic stage,maternal effect,heat sensitive,some die during embryonic stage,cell growth defective,female sterile,male sterile,visible,cold sensitive,sterile,body color defective,partially lethal - majority die,some die during pupal stage" "fusome | germline clone,oocyte nucleus,germline clone,egg,follicle cell,microtubule & oocyte,dorsal appendage,egg operculum,micropyle,posterior aeropyle,egg chamber,microtubule & egg chamber,mesothoracic tergum" DRSC04703 IEK 2.104579471 0.751532075 2.493704351 1.279685665 0.010062666 -2.253576783 FBgn0260571 MENE-Z33 - http://flybase.org/reports/FBgn0260571 gene - - - MENE-Z33 - - 11-Aug-17 DroID_v2017_08 - - - - - - "eye disc,somatic clone" FBgn0001058 Fs(3)Kun Female sterile (3) Kun http://flybase.org/reports/FBgn0001058 - gene - - - "Kan, Fs(3)Sz17, Fs(3)Kun" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" female pronucleus | maternal effect FBgn0003598 Su(var)3-7 Suppressor of variegation 3-7 http://flybase.org/reports/FBgn0003598 - protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Su(var)205 positive regulation of chromatin silencing at centromere ; GO:0090053 | inferred from mutant phenotype dosage compensation by hyperactivation of X chromosome ; GO:0009047 | inferred from mutant phenotype positive regulation of heterochromatin assembly ; GO:0031453 | inferred from genetic interaction with mle "heterochromatin ; GO:0000792 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay heterochromatin ; GO:0000792 | traceable author statement pericentric heterochromatin ; GO:0005721 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | traceable author statement chromosome, centromeric region ; GO:0000775 |" "Su(var)3-7, SU(VAR)3-7, Suvar(3)7, Su-var(3)7, Su(var)(3)7, Su(var)(3)3, l(3)87El, CG8599, DmSu(var)3-7, Su(Var)3-7, Suv3-7" IPR004210:BESS motif CG8599 11-Aug-17 DroID_v2017_08 - - - - - - "endomitotic cell cycle defective,lethal - all die before end of second instar larval stage,recessive,rescuable maternal effect,some die during second instar larval stage,enhancer of variegation,non-enhancer of variegation,lethal,suppressor of variegation,wild-type,dominant,viable,lethal - all die before end of larval stage,maternal effect,some die during larval stage,fertile,non-suppressor of variegation" "prothoracic gland,polytene chromosome | male3-77.1A.5'), with Su(var)3-77.1A.3',polytene chromosome | male3-77.1A.mid), with Su(var)3-77.1A.3',adult cuticle & abdomen3-79.5'),macrochaeta,humeral bristle,sex comb,ommatidium,wing,polytene chromosome chromocenter, with Su(var)3-714.3', Su(var)3-714.5'/Su(var)3-79.5',polytene chromosome | male3-714.5'),polytene chromosome chromocenter3-714.5'),polytene chromosome chromocenter, with Su(var)3-79.3', Su(var)3-714.5'/Su(var)3-79.5',polytene chromosome | male, with Su(var)3-77.1A.5'/Su(var)3-77.1A.mid,polytene chromosome | male3-714.3'),polytene chromosome chromocenter3-714.3'),polytene chromosome chromocenter3-79.5'), with Su(var)3-714.3', Su(var)3-79.3',adult cuticle & abdomen3-79.3'),polytene chromosome chromocenter3-714.5'), with Su(var)3-714.3', Su(var)3-79.3'" FBgn0060982 l(3)S028310 lethal (3) S028310 http://flybase.org/reports/FBgn0060982 gene - - - "0283/10, l(3)S028310" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0283477 SF2 Splicing factor 2 http://flybase.org/reports/FBgn0283477 protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Trn-SR mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with tra2 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of mRNA 3'-end processing ; GO:0031440 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype regulation of transcriptional start site selection at RNA polymerase II promoter ; GO:0001178 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "SF2, dASF, 154911_at, ASF/SF2, dSF2/ASF, ASF, dmSF2/p28, CG6987, cg6987, SRp30, dSRp30" "IPR034520:SRSF1, RNA recognition motif 1, IPR000504:RNA recognition motif domain" CG6987 11-Aug-17 DroID_v2017_08 "Drer\srsf1b, Drer\srsf9, Drer\srsf5b, Drer\srsf6b, Drer\srsf6a, Drer\srsf4, Drer\srsf5a, Drer\srsf1a" "Scer\GBP2, Scer\HRB1, Scer\NPL3" "Cele\rsp-2, Cele\rsp-1, Cele\rsp-3, Cele\rsp-5" "Xtro\srsf5, Xtro\srsf1, Xtro\krt5.1, Xtro\srsf6, Xtro\srsf9, Xtro\srsf4" "Mmus\Srsf1, Mmus\Srsf4, Mmus\Srsf9, Mmus\Srsf6, Mmus\Srsf5" "Hsap\SRSF1, Hsap\SRSF5, Hsap\SRSF4, Hsap\SRSF6, Hsap\SRSF9" "lethal - all die before end of pupal stage,some die during pupal stage,visible,heat sensitive,lethal,neuroanatomy defective" "retina,eye,ommatidium,embryonic/larval neuroblast,ganglion mother cell" DRSC16845 IE 1.692370139 0.360222202 -6.698922673 2.744157998 0.520519211 -1.096605845 FBgn0038542 TyrR Tyramine receptor http://flybase.org/reports/FBgn0038542 protein_coding_gene G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity tyramine receptor activity ; GO:0008226 | inferred from direct assay phospholipase C-activating dopamine receptor signaling pathway ; GO:0060158 | inferred from biological aspect of ancestor with PANTHER:PTN000665343 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay learning ; GO:0007612 | inferred from biological aspect of ancestor with PANTHER:PTN000665343 tyramine signaling pathway ; GO:0071928 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity cellular response to amine stimulus ; GO:0071418 | inferred from direct assay positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway ; GO:1900738 | inferred from direct assay octopamine or tyramine signaling pathway ; GO:0007211 | inferred by curator from GO:0008226 adenylate cyclase-activating dopamine receptor signaling pathway ; GO:0007191 | inferred from biological aspect of ancestor with PANTHER:PTN000665343 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0008226 inferred from direct assay "DmCG7431, anon-WO0170980.83, anon-WO0170980.82, CG7431, TyrR, DrmTR, TR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG7431 11-Aug-17 DroID_v2017_08 "Drer\drd7, Drer\drd4a, Drer\drd2a, Drer\drd4b, Drer\htr4, Drer\drd1a, Drer\si:dkey-247m21.3, Drer\drd1b, Drer\drd6b, Drer\drd2b, Drer\LOC563567, Drer\hrh2b, Drer\drd3, Drer\drd4-rs, Drer\drd2l, Drer\LOC567498" - "Cele\dop-4, Cele\tyra-3" "Xtro\htr4, Xtro\drd2" "Mmus\Drd3, Mmus\Hrh1, Mmus\Drd4, Mmus\Drd5, Mmus\Hrh2, Mmus\Adra1d, Mmus\Drd1, Mmus\Htr4, Mmus\Drd2" "Hsap\DRD1, Hsap\ADRA1D, Hsap\DRD5, Hsap\DRD2, Hsap\HTR4, Hsap\HRH1, Hsap\DRD4, Hsap\DRD3, Hsap\HRH2" "viable,visible,fertile" trichogen cell FBgn0262710 ifm(2)RS3 - http://flybase.org/reports/FBgn0262710 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0027375 RecQ5 RecQ5 helicase http://flybase.org/reports/FBgn0027375 "FBgn0024312, FBgn0027689" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 four-way junction helicase activity ; GO:0009378 | inferred from biological aspect of ancestor with PANTHER:PTN000344873 ATP-dependent 3'-5' DNA helicase activity ; GO:0043140 | inferred from biological aspect of ancestor with PANTHER:PTN000344873 single-stranded DNA-dependent ATP-dependent DNA helicase activity ; GO:0017116 | inferred from direct assay GTP binding ; GO:0005525 | inferred from direct assay helicase activity ; GO:0004386 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from direct assay DNA helicase activity ; GO:0003678 | inferred from sequence or structural similarity with HGNC:9950 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000344873 double-strand break repair via single-strand annealing ; GO:0045002 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from biological aspect of ancestor with PANTHER:PTN000344874 mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from direct assay response to X-ray ; GO:0010165 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype negative regulation of mitotic cell cycle ; GO:0045930 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000344873 chromosome ; GO:0005694 | inferred from biological aspect of ancestor with PANTHER:PTN000344873 nucleus ; GO:0005634 | inferred from direct assay "dmRecQ5b, DmRECQ5, RECQ5/QE, Dm RECQ5/QE, RECQ5, RECQE, DQ1, Dq1, Q1, anon-EST:Posey293, CG4879, RecQ5, recq5, dRecQ5" "IPR001650:Helicase, C-terminal, IPR004589:DNA helicase, ATP-dependent, RecQ type, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR032284:ATP-dependent DNA helicase RecQ, zinc-binding domain" CG4879 11-Aug-17 DroID_v2017_08 "Drer\recql, Drer\blm, Drer\recql5" Scer\SGS1 "Cele\rcq-5, Cele\him-6, Cele\wrn-1, Cele\K02F3.12" - "Mmus\Recql5, Mmus\Wrn, Mmus\Blm, Mmus\Recql" "Hsap\WRN, Hsap\RECQL5, Hsap\RECQL, Hsap\BLM" " adult stage && oogenesis stage | stage S10 , embryonic stage | early , adult stage && oogenesis stage | stage S11,12 , embryonic stage -- adult stage " " nurse cell

,

ubiquitous , oocyte

" "viable,fertile,developmental rate defective,radiation sensitive,DNA repair defective,mitotic cell cycle defective,maternal effect" "nucleus | maternal effect,embryo,maternal effect,centrosome | maternal effect,eye,ommatidial precursor cluster,interommatidial bristle" FBgn0039147 CG10694 - http://flybase.org/reports/FBgn0039147 protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR015360 "proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from electronic annotation with InterPro:IPR015360 nucleotide-excision repair ; GO:0006289 | inferred from electronic annotation with InterPro:IPR004806, InterPro:IPR015360" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR004806 CG10694 "IPR000626:Ubiquitin domain, IPR009060:UBA-like, IPR015940:Ubiquitin-associated domain, IPR015360:XPC-binding domain, IPR029071:Ubiquitin-related domain, IPR004806:UV excision repair protein Rad23" CG10694 11-Aug-17 DroID_v2017_08 "Drer\rad23b, Drer\rad23aa, Drer\rad23ab" "Scer\RAD23, Scer\MDY2" "Cele\rad-23, Cele\mei-2, Cele\F47G4.4" Xtro\rad23b "Mmus\Nos1, Mmus\Rad23b, Mmus\Rad23a" "Hsap\RAD23B, Hsap\RAD23A, Hsap\NOS1" viable FBgn0085224 CG34195 - http://flybase.org/reports/FBgn0085224 protein_coding_gene tRNA (cytosine) methyltransferase activity ; GO:0016427 | inferred from sequence or structural similarity with HGNC:18272 tRNA methylation ; GO:0030488 | inferred from sequence or structural similarity with HGNC:18272 cellular_component ; GO:0005575 | no biological data available "CG34195, CG4989" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR026113:Methyltransferase-like" CG34195 11-Aug-17 DroID_v2017_08 "Drer\mettl8, Drer\mettl2a, Drer\mettl6" Scer\ABP140 "Cele\metl-2, Cele\ZK1058.5" "Xtro\mettl6, Xtro\mettl2b" "Mmus\Mettl6, Mmus\Mettl2, Mmus\Mettl8" "Hsap\METTL8, Hsap\ALKBH8, Hsap\METTL6, Hsap\METTL2A, Hsap\METTL2B" "viable,fertile" FBgn0027567 CG8108 - http://flybase.org/reports/FBgn0027567 - protein_coding_gene - positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype - "BcDNA:GH07921, CG8108" IPR026811:Cip1-interacting zinc finger protein CG8108 11-Aug-17 DroID_v2017_08 "Drer\ciz1b, Drer\ciz1a" Scer\REB1 - - Mmus\Ciz1 Hsap\CIZ1 "lethal - all die before end of pupal stage,some die during pupal stage,female sterile" DRSC09675 IK 9.333957591 5.168792171 0.247770702 -0.78093577 1.181377442 2.623217742 FBgn0000166 bcd bicoid http://flybase.org/reports/FBgn0000166 "FBgn0040059, FBgn0014130, FBgn0014131, FBgn0015909, FBgn0015910, FBgn0015911, FBgn0015912" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 morphogen activity ; GO:0016015 | non-traceable author statement translation repressor activity ; GO:0030371 | inferred from genetic interaction with eIF4EHP protein binding ; GO:0005515 | inferred from physical interaction with bin3 translation regulator activity ; GO:0045182 | traceable author statement transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Bin1 protein binding ; GO:0005515 | inferred from physical interaction with fsd transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay mRNA 3'-UTR binding ; GO:0003730 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with eIF4EHP" "negative regulation of translation ; GO:0017148 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype anterior/posterior axis specification ; GO:0009948 | traceable author statement anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement maternal determination of anterior/posterior axis, embryo ; GO:0008358 | non-traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement maternal determination of anterior/posterior axis, embryo ; GO:0008358 | traceable author statement anterior region determination ; GO:0007355 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from genetic interaction with eIF4EHP regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype regulation of translation ; GO:0006417 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement negative regulation of translation ; GO:0017148 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0003705 "bcd, BCD, Bcd, bic, prd4, mum, CG1034, BG:DS00276.7, bicoid, Bicoid" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG1034 11-Aug-17 DroID_v2017_08 Drer\gsx2 "Scer\PHO2, Scer\YOX1, Scer\YHP1" "Cele\F47G4.4, Cele\mei-2" - "Mmus\Gsx2, Mmus\Nos1, Mmus\Nkx2-2" "Hsap\NKX2-2, Hsap\NOS1, Hsap\GSX2" " adult stage && oogenesis stage | stage S5-7 , adult stage && oogenesis stage , embryonic stage | stage 4 , embryonic stage | stage 1-2 , oogenesis stage , oogenesis stage | stage S10 , embryonic stage , embryonic stage | 0-3 hr , embryonic stage | early , embryonic stage | stage 3-4 , oogenesis stage | stage S10B , adult stage && oogenesis stage | stage S10 , adult stage && oogenesis stage | stage S13-14 , embryonic stage | 0-2 hr , embryonic stage | 2-4 hr , embryonic stage | stage <5 " " oocyte | anterior

, nurse cell

{ $ exu* } , nurse cell

,

90-100% egg length ,

anterior , ovary

, organism | 80-100% egg length

, ovary

{ $ swa* } , organism

,

{ $ swa* } , ovary

{ 0 stau* } ,

{ $ stau* } ,

{ $ exu* } , organism | anterior posterior gradient

, oocyte

" " embryonic stage | stage 1-5 , embryonic stage | 0-3.25 hr , embryonic stage | stage 4 , embryonic stage | early , embryonic stage | stage 4-6 " "

20-100% egg length , organism

,

anterior posterior gradient ,

anterior ,

70-100% egg length , organism | 90-100% egg length

" "wild-type,lethal,male,visible,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female,increased cell death,homeotic,sterile,female sterile,recessive,partially lethal - majority die,germline clone,non-rescuable maternal effect,heat sensitive" "embryo,anterior,organism,maternal effect,larval head,syncytial blastoderm embryo,wing,female,wing pouch,cephalic furrow,labral segment,head,embryonic/first instar larval cuticle,embryonic/larval cuticle,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,denticle belt,cephalopharyngeal skeleton,presumptive embryonic/larval peripheral nervous system,embryonic neuroblast & abdomen,larval thorax,ocular segment,telson,embryonic thoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,embryonic gnathal segment,mouth hooks,median tooth,dorsal closure embryo,gonadal sheath proper primordium,germline cell,embryonic/larval posterior spiracle,ectopic,embryonic thorax,embryonic head,embryonic abdomen,embryonic/larval salivary gland,pole cell,extended germ band embryo,embryonic/larval spiracle,embryonic head segment,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,terminalia,abdomen,filzkorper,thorax,germline clone,embryonic abdominal segment,posterior,abdominal segment 7,abdominal segment 8,abdominal segment 9,embryonic/larval midgut,lateral process,dorsal bridge,embryonic/larval pharynx" FBgn0022786 Hira Hira http://flybase.org/reports/FBgn0022786 FBgn0027940 protein_coding_gene nucleosome binding ; GO:0031491 | inferred from biological aspect of ancestor with PANTHER:PTN000352669 chromatin binding ; GO:0003682 | inferred from direct assay transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN000352669 "fertilization, exchange of chromosomal proteins ; GO:0035042 | inferred from mutant phenotype sperm chromatin decondensation ; GO:0035041 | inferred from mutant phenotype regulation of chromatin silencing ; GO:0031935 | inferred from biological aspect of ancestor with PANTHER:PTN000352669 chromatin remodeling ; GO:0006338 | inferred from mutant phenotype DNA replication-independent nucleosome assembly ; GO:0006336 | inferred from mutant phenotype" male germ cell nucleus ; GO:0001673 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000352669 germinal vesicle ; GO:0042585 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "HIRA, ssm, hira, CG12153, dHira, Dhh, dhira, Hira" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR011494:TUP1-like enhancer of split, IPR019015:HIRA B motif, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR031120:WD repeat HIR1" CG12153 11-Aug-17 DroID_v2017_08 Drer\hira "Scer\HIR2, Scer\HIR1" Cele\K10D2.1 Xtro\hira Mmus\Hira "Hsap\HIRA, Hsap\C22orf39" " adult stage | female , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage | early " " ovary

, oocyte

, nurse cell

" "partially lethal - majority die,paternal effect,recessive,some die during embryonic stage,lethal - all die before end of embryonic stage,non-rescuable maternal effect,enhancer of variegation,non-enhancer of variegation,female sterile,viable,male fertile,maternal effect" "male pronucleus,male pronucleus | non-rescuable maternal effect,male pronucleus & nuclear membrane | non-rescuable maternal effect,embryonic/first instar larval cuticle,maternal effect,cephalopharyngeal skeleton,male pronucleus | maternal effect,mitotic cell cycle | maternal effect,male pronucleus | maternal effectct4b1)" FBgn0014338 lphA larval photokinesis A http://flybase.org/reports/FBgn0014338 - gene molecular_function ; GO:0003674 | no biological data available larval behavior ; GO:0030537 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available lphA - - 11-Aug-17 DroID_v2017_08 - - - - - - "visual behavior defective,behavior defective" FBgn0003963 ush u-shaped http://flybase.org/reports/FBgn0003963 - protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein binding ; GO:0005515 | inferred from physical interaction with srp transcription factor binding ; GO:0008134 | traceable author statement transcription factor binding ; GO:0008134 | inferred from mutant phenotype transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from biological aspect of ancestor with PANTHER:PTN000311050 RNA polymerase II activating transcription factor binding ; GO:0001102 | inferred from physical interaction with pnr" "terminal region determination ; GO:0007362 | inferred from genetic interaction with tor amnioserosa maintenance ; GO:0046665 | traceable author statement negative regulation of cell fate specification ; GO:0009996 | traceable author statement amnioserosa maintenance ; GO:0046665 | inferred from mutant phenotype dorsal closure, leading edge cell fate determination ; GO:0007393 | non-traceable author statement pigment metabolic process ; GO:0042440 | traceable author statement head involution ; GO:0008258 | non-traceable author statement lymph gland development ; GO:0048542 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor germ-band shortening ; GO:0007390 | traceable author statement germ-band shortening ; GO:0007390 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay negative regulation of crystal cell differentiation ; GO:0042690 | traceable author statement heart development ; GO:0007507 | traceable author statement larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement negative regulation of sequence-specific DNA binding transcription factor activity ; GO:0043433 | inferred from direct assay chaeta development ; GO:0022416 | inferred from genetic interaction with CtBP regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay hemopoiesis ; GO:0030097 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "ush, CG2762, dFOG, FOG, ushaped, Ush, u-sh, l(2)19, ZFPM2, USH" "IPR013087:Zinc finger C2H2-type, IPR034731:Zinc finger CCHC FOG-type" CG2762 11-Aug-17 DroID_v2017_08 "Drer\zfpm2a, Drer\zfpm1, Drer\zfpm2b" - - "Xtro\zfpm1, Xtro\zfpm2, Xtro\znf341" "Mmus\Zfp445, Mmus\Zfpm2, Mmus\Zfpm1" "Hsap\ZFPM1, Hsap\ZNF445, Hsap\ZFPM2" " larval stage | third instar , embryonic stage | 4-8 hr , embryonic stage | stage 6 , larval stage | third instar stage 2 , pupal stage && adult stage " " dorsal ectoderm anlage

, imaginal disc | restricted

" "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,wild-type,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority live,lethal - all die before end of P-stage,some die during pharate adult stage,visible,recessive,heat sensitive,hyperplasia,decreased cell number,increased cell number,lethal,dominant,planar polarity defective,partially lethal - majority die,some die during pupal stage,size defective,lethal - all die before end of pupal stage" "adult thorax,posterior scutellar bristle | adult stage,anterior scutellar bristle | adult stage,posterior dorsocentral bristle | adult stage,anterior dorsocentral bristle | adult stage,anterior postalar bristle | adult stage,posterior supraalar bristle | adult stage,anterior supraalar bristle | adult stage,presutural bristle | adult stage,posterior notopleural bristle | adult stage,anterior notopleural bristle | adult stage,direct flight muscle,dorsal medial muscle,dorsocentral bristle,postvertical bristle,scutellar bristle,adult external thorax,heat sensitive,cardioblast,ectopic,pericardial cell,mesoderm,crystal cell,extended germ band embryo,dorsal closure embryo,embryonic head,cephalopharyngeal skeleton,dorsal bridge,vertical bridge,cuticle,filzkorper,amnioserosa,cell non-autonomous,somatic clone,dorsocentral bristle & axon,plasmatocyte,embryonic/larval lymph gland,lamellocyte,hemocyte,scutellum,dorsal,epidermis,anterior,posterior,crystal cell | embryonic stage,precursor,fat body,eye disc,eye,antenna,ommatidium,heart primordium,plasmatocyte | third instar larval stage,posterior signalling centre of lymph gland primary lobe,chorion,drug conditional,lamellocyte | third instar larval stage,hemocyte | third instar larval stage,embryonic/larval lymph gland | second instar larval stage" DRSC00843 IE 2.858683153 5.566237244 3.627907376 -0.632702047 -1.496566144 0.077487084 FBgn0003044 Pcl Polycomblike http://flybase.org/reports/FBgn0003044 FBgn0010678 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24338 inferred from physical interaction with UniProtKB:Q94517 inferred from physical interaction with UniProtKB:Q9NJG9 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P42124 methylated histone binding ; GO:0035064 | NOT inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay methylated histone binding ; GO:0035064 | NOT inferred from direct assay inferred from key residues chromatin binding ; GO:0003682 | inferred from direct assay" "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from direct assay" ESC/E(Z) complex ; GO:0035098 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG5109, PCL, pcl, l(2)s1859, Pcl, dPcl" "IPR025894:Polycomb-like MTF2 factor 2, C-terminal domain, IPR001965:Zinc finger, PHD-type, IPR002999:Tudor domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5109 11-Aug-17 DroID_v2017_08 "Drer\phf1, Drer\ints12, Drer\phf19, Drer\mtf2" "Scer\ZDS1, Scer\IRR1" Cele\asp-2 "Xtro\mtf2, Xtro\ints12, Xtro\phf19, Xtro\phf1" "Mmus\Ints12, Mmus\Bach1, Mmus\Phf19, Mmus\Mtf2, Mmus\Phf1" "Hsap\MTF2, Hsap\PHF1, Hsap\PHF19, Hsap\INTS12" embryonic stage

ubiquitous larval stage larval salivary gland

"visible,dominant,homeotic,non-suppressor of variegation,non-enhancer of variegation,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,immune response defective,lethal,wild-type,viable,suppressor of variegation,somatic clone,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "sex comb,ectopic,mesothoracic leg,metathoracic leg,mesothoracic leg & sex comb | ectopic,hemocyte,plasmatocyte,crystal cell,wing,prothoracic leg,adult abdominal segment 4,antenna,wing vein L5,anterior compartment,posterior compartment,metathoracic metatarsus,metathoracic coxa,metathoracic trochanter,metathoracic femur,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7,female accessory gland,midgut constriction,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,larval abdominal segment 1,larval abdominal segment 2,larval abdominal segment 3,larval abdominal segment 4,larval abdominal segment 5,larval abdominal segment 6,larval abdominal segment 7,larval abdominal segment 8,germline clone,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,adult abdominal segment 2,somatic clone,adult abdominal segment 3,adult abdominal segment 5,adult abdominal segment 6,male,embryonic/larval neuroblast,ganglion mother cell" FBgn0025352 Thiolase Thiolase http://flybase.org/reports/FBgn0025352 FBgn0010464 protein_coding_gene acetyl-CoA C-acyltransferase activity ; GO:0003988 | inferred from biological aspect of ancestor with PANTHER:PTN000432120 long-chain-3-hydroxyacyl-CoA dehydrogenase activity ; GO:0016509 | inferred from sequence or structural similarity with UniProtKB:P55084 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype fatty acid beta-oxidation ; GO:0006635 | inferred from mutant phenotype fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with UniProtKB:P55084 mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence model microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial fatty acid beta-oxidation multienzyme complex ; GO:0016507 | inferred from sequence or structural similarity with UniProtKB:P55084 "CG4581, Thiolase, thiolase, Mtpbeta, l(2)k09828, ACoT" "IPR002155:Thiolase, IPR016039:Thiolase-like, IPR020610:Thiolase, active site, IPR020613:Thiolase, conserved site, IPR020615:Thiolase, acyl-enzyme intermediate active site, IPR020616:Thiolase, N-terminal, IPR020617:Thiolase, C-terminal" CG4581 11-Aug-17 DroID_v2017_08 Drer\hadhb Scer\POT1 Cele\B0303.3 Xtro\hadhb Mmus\Hadhb Hsap\HADHB "lethal,recessive,viable,fertile,short lived,locomotor behavior defective" "eye photoreceptor cell,cell autonomous,somatic clone,adult fat body,lipid particle" FBgn0002677 mat(2)syn-E maternal effect syncytial blastoderm arrest E http://flybase.org/reports/FBgn0002677 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "PJ60, mat(2)synPJ50, mat(2)syn-E" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "pole cell,maternal effect" FBgn0004587 B52 B52 http://flybase.org/reports/FBgn0004587 "FBgn0004424, FBgn0010262, FBgn0011022, FBgn0013330" protein_coding_gene mRNA binding ; GO:0003729 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Trn-SR "mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of mRNA splicing, via spliceosome ; GO:0048024 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from direct assay regulation of mRNA 3'-end processing ; GO:0031440 | inferred from mutant phenotype regulation of transcriptional start site selection at RNA polymerase II promoter ; GO:0001178 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay omega speckle ; GO:0035062 | NOT inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay nuclear speck ; GO:0016607 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 polytene chromosome ; GO:0005700 | inferred from direct assay "B52/SRp55, SRp55, CG10851, RRM8, dSRp55, E(Dfd), B52/dSRp55, l(3)s2249, rrm8, E726, SR55, Rbp8, RSp55, MabB52, B52" IPR000504:RNA recognition motif domain CG10851 11-Aug-17 DroID_v2017_08 "Drer\srsf1b, Drer\srsf5a, Drer\srsf9, Drer\srsf6a, Drer\srsf4, Drer\srsf1a, Drer\srsf6b, Drer\srsf5b" Scer\NPL3 "Cele\ztf-4, Cele\rsp-3, Cele\rsp-1, Cele\rsp-2, Cele\rsp-5" "Xtro\srsf6, Xtro\srsf4, Xtro\srsf1, Xtro\krt5.1, Xtro\srsf5, Xtro\srsf9" "Mmus\Srsf5, Mmus\Srsf4, Mmus\Srsf9, Mmus\Srsf6, Mmus\Srsf1" "Hsap\SRSF1, Hsap\SRSF9, Hsap\SRSF4, Hsap\SRSF5, Hsap\SRSF6" "lethal,recessive,eye color defective,lethal - all die before end of larval stage,some die during larval stage,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "pigment cell,sternite,macrochaeta,wing,sternopleural bristle,adult salivary gland,retina,eye,embryonic/larval salivary gland,embryonic/larval brain,trichogen cell,mesothoracic tergum" FBgn0001763 l(1)M22 lethal (1) M22 http://flybase.org/reports/FBgn0001763 - gene - - - l(1)M22 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0003696 thi thickhead http://flybase.org/reports/FBgn0003696 - gene - - - thi - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" embryonic head FBgn0020773 vid visual system disorganizer http://flybase.org/reports/FBgn0020773 - gene - - - vid - - 11-Aug-17 DroID_v2017_08 - - - - - - "optic lobe,somatic clone,eye photoreceptor cell,adult brain,ommatidium,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,pigment cell" FBgn0025726 unc-13 unc-13 http://flybase.org/reports/FBgn0025726 FBgn0013637 protein_coding_gene diacylglycerol binding ; GO:0019992 | inferred from electronic annotation with InterPro:IPR027080 calmodulin binding ; GO:0005516 | traceable author statement protein N-terminus binding ; GO:0047485 | inferred from sequence or structural similarity with UniProtKB:Q62768 syntaxin-1 binding ; GO:0017075 | inferred from sequence or structural similarity with UniProtKB:Q62768 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 neurotransmitter secretion ; GO:0007269 | inferred from sequence or structural similarity with UniProtKB:Q62768 synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity lateral inhibition ; GO:0046331 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype synaptic vesicle priming ; GO:0016082 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity neuron projection ; GO:0043005 | inferred from sequence or structural similarity with UniProtKB:Q62768 synaptic vesicle ; GO:0008021 | non-traceable author statement postsynaptic membrane ; GO:0045211 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from biological aspect of ancestor with PANTHER:PTN000826129 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q62770 terminal bouton ; GO:0043195 | inferred from direct assay presynaptic membrane ; GO:0042734 | inferred from sequence or structural similarity with UniProtKB:Q62768 "DUNC-13, Dunc-13, Munc-13/UNC-13, dUnc-13, Dunc13, dUNC-13, CG2999, Munc-13, drunc13, dunc-13, UNC-13-B, UNC-13, l(4)ry16, unc-13, Unc-13, unc, Unc13A, Unc13B" "IPR000008:C2 domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR010439:Calcium-dependent secretion activator domain, IPR014770:Munc13 homology 1, IPR014772:Mammalian uncoordinated homology 13, domain 2, IPR019558:Mammalian uncoordinated homology 13, subgroup, domain 2, IPR027080:Uncoordinated protein 13 (Unc-13)" CG2999 11-Aug-17 DroID_v2017_08 "Drer\LOC101885741, Drer\LOC101884666, Drer\unc13bb, Drer\si:dkey-110c1.7" - "Cele\unc-13, Cele\C16C8.16, Cele\Y116A8C.11" "Xtro\unc13a, Xtro\LOC100489443" "Mmus\Unc13b, Mmus\Unc13c, Mmus\Unc13a" "Hsap\UNC13A, Hsap\L1TD1, Hsap\UNC13C, Hsap\UNC13B" " pupal stage , adult stage " adult head

"viable,fertile,paralytic,recessive,neurophysiology defective,lethal,feeding behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective" synaptic vesicle FBgn0022962 spongecake spongecake http://flybase.org/reports/FBgn0022962 - gene - - - spongecake - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,recessive,heat sensitive,lethal" "medulla,lamina,lobula,optic lobe & neuropil,optic lobe" FBgn0037634 hng2 hinge2 http://flybase.org/reports/FBgn0037634 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - - "CG8359, hng2" "IPR004210:BESS motif, IPR006578:MADF domain" CG8359 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-207i20.3, Drer\zgc:152938, Drer\LOC100330838" - "Cele\madf-4, Cele\madf-10, Cele\madf-2, Cele\madf-5, Cele\madf-9, Cele\madf-3, Cele\madf-8" - - - "flightless,viable,fertile" wing hinge DRSC16412 K 1.155081088 0.227484148 0.091084622 -0.471310292 -0.664829853 -1.727014753 FBgn0024554 l(3)L4111 lethal (3) L4111 http://flybase.org/reports/FBgn0024554 - gene - - - "l(3)L4111, Mgn95009" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0037036 Sems Seminase http://flybase.org/reports/FBgn0037036 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype zymogen activation ; GO:0031638 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sperm storage ; GO:0046693 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 extracellular space ; GO:0005615 | inferred from direct assay "CG10586, SP168, sems, Sems" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG10586 11-Aug-17 DroID_v2017_08 - - "Cele\try-5, Cele\try-1, Cele\svh-1" - Mmus\Hgf "Hsap\HGF, Hsap\TMPRSS5" "viable,mating behavior defective" FBgn0265816 CR44605 - http://flybase.org/reports/FBgn0265816 non_protein_coding_gene - - - "lincRNA.178, CR44605" - CR44605 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0062413 Ctr1A Copper transporter 1A http://flybase.org/reports/FBgn0062413 protein_coding_gene "copper ion transmembrane transporter activity ; GO:0005375 | inferred by curator from GO:0005886,GO:0006878 copper uptake transmembrane transporter activity ; GO:0015088 | inferred from mutant phenotype copper ion transmembrane transporter activity ; GO:0005375 | inferred from direct assay" "copper ion transmembrane transport ; GO:0035434 | inferred from electronic annotation with InterPro:IPR007274 copper ion transport ; GO:0006825 | inferred from mutant phenotype cellular copper ion homeostasis ; GO:0006878 | inferred from mutant phenotype plasma membrane copper ion transport ; GO:0015679 | inferred by curator from GO:0005886,GO:0006878 regulation of heart rate ; GO:0002027 | inferred from mutant phenotype copper ion transport ; GO:0006825 | inferred from direct assay" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007274 plasma membrane ; GO:0005886 | inferred from direct assay "CG3977, BcDNA:RH42635, Ctr1A, DmCtr1A, ctr1A" IPR007274:Ctr copper transporter CG3977 11-Aug-17 DroID_v2017_08 "Drer\slc31a2, Drer\slc31a1" "Scer\CTR2, Scer\CTR1, Scer\CTR3" "Cele\F58G6.3, Cele\K12C11.3, Cele\F31E8.4, Cele\K12C11.6, Cele\F27C1.2, Cele\F58G6.9, Cele\F58G6.7, Cele\K12C11.7, Cele\Y58A7A.1, Cele\F01G12.1" "Xtro\slc31a2, Xtro\slc31a1" "Mmus\Slc31a2, Mmus\Slc31a1" "Hsap\SLC31A1, Hsap\SLC31A2" "visible,recessive,maternal effect,lethal,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,body color defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "mouth hooks,spiracle primordium,maternal effect,abdomen,mesothoracic bristle,embryonic/larval heart,adult cuticle,trichogen cell,mesothoracic tergum,eye,ommatidium" DRSC18336 I -0.378167999 -2.130772434 -0.884756047 0.201944141 1.370484247 1.041430506 FBgn0030092 fh frataxin http://flybase.org/reports/FBgn0030092 protein_coding_gene "iron chaperone activity ; GO:0034986 | inferred from direct assay ferric iron binding ; GO:0008199 | inferred from biological aspect of ancestor with PANTHER:PTN002314443 ferroxidase activity ; GO:0004322 | inferred from biological aspect of ancestor with PANTHER:PTN002314443 ferrous iron binding ; GO:0008198 | inferred from biological aspect of ancestor with PANTHER:PTN002314443 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from biological aspect of ancestor with PANTHER:PTN002314443" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR017789 mitochondrion organization ; GO:0007005 | inferred from biological aspect of ancestor with PANTHER:PTN000423706 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype iron incorporation into metallo-sulfur cluster ; GO:0018283 | inferred from biological aspect of ancestor with PANTHER:PTN002314443 response to hydrogen peroxide ; GO:0042542 | inferred from mutant phenotype positive regulation of ecdysteroid biosynthetic process ; GO:0045998 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cellular iron ion homeostasis ; GO:0006879 | inferred from sequence or structural similarity with UniProtKB:Q16595 regulation of mitochondrial membrane potential ; GO:0051881 | inferred from direct assay axonal transport of mitochondrion ; GO:0019896 | inferred from direct assay cellular iron ion homeostasis ; GO:0006879 | inferred from biological aspect of ancestor with PANTHER:PTN002314443 positive regulation of heart contraction ; GO:0045823 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from biological aspect of ancestor with PANTHER:PTN002314443 response to iron ion ; GO:0010039 | inferred from mutant phenotype lipid catabolic process ; GO:0016042 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from sequence model mitochondrion ; GO:0005739 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q16595 "DFH, dfh, X25, CG8971, BcDNA:AT09528, fh, Dfh" "IPR002908:Frataxin/CyaY, IPR017789:Frataxin, IPR020895:Frataxin conserved site" CG8971 11-Aug-17 DroID_v2017_08 Drer\fxn Scer\YFH1 Cele\frh-1 - Mmus\Fxn Hsap\FXN "developmental rate defective,partially,short lived,chemical sensitive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,locomotor rhythm defective,gravitaxis defective,conditional,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,viable,some die during third instar larval stage,locomotor behavior defective,chemical resistant,stress response defective,long lived" "ventral nerve cord | third instar larval stage,motor neuron | third instar larval stage,mitochondrion | third instar larval stageD42,adult heart,RU486 conditional,A1-7 dorsal acute muscle 3,A1-7 dorsal oblique muscle 3,A1-7 dorsal oblique muscle 4,motor neuron,sensory neuron,embryonic/larval pericardial cell" FBgn0060526 l(3)S101801b lethal (3) S101801b http://flybase.org/reports/FBgn0060526 gene - - - "1018/01, l(3)S101801b" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0005268 l(3)SG88 lethal (3) SG88 http://flybase.org/reports/FBgn0005268 - gene - - - l(3)SG88 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0043478 l(3)66EFh lethal (3) 66EFh http://flybase.org/reports/FBgn0043478 gene - - - l(3)66EFh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0030104 CG15368 - http://flybase.org/reports/FBgn0030104 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000058 - - CG15368 "IPR000058:Zinc finger, AN1-type" CG15368 11-Aug-17 DroID_v2017_08 "Drer\zfand5a, Drer\faub, Drer\ubc, Drer\zgc:56596, Drer\zfand4, Drer\faua, Drer\zfand5b, Drer\isg15, Drer\zfand6, Drer\zgc:77486" Scer\UBI4 "Cele\F56F3.4, Cele\F22D6.2" "Xtro\ubl4a, Xtro\zfand4, Xtro\ubc, Xtro\zfand6, Xtro\fau, Xtro\zfand5" "Mmus\Ubd, Mmus\Zfand5, Mmus\Isg15, Mmus\Ubl4b, Mmus\Zfand6, Mmus\Ubl4a, Mmus\Zfand4, Mmus\Oas1g, Mmus\Ubb, Mmus\Oas1a, Mmus\Fau, Mmus\Oasl2, Mmus\Oas2, Mmus\Oas3, Mmus\Oasl1" "Hsap\ZFAND6, Hsap\OAS3, Hsap\UBB, Hsap\OAS2, Hsap\ZFAND5, Hsap\ZFAND4, Hsap\OASL, Hsap\UBC, Hsap\UBL4A, Hsap\UBD, Hsap\UBL4B, Hsap\ISG15, Hsap\OAS1" "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0003700 thm thin macros http://flybase.org/reports/FBgn0003700 - gene - - - thm - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" macrochaeta FBgn0005017 dipp-8 defective in phototaxis plasticity 8 http://flybase.org/reports/FBgn0005017 - gene - - - dipp-8 - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,visual behavior defective,phototaxis defective" FBgn0030522 CG11103 - http://flybase.org/reports/FBgn0030522 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:LP03404, CG11103" IPR007829:TM2 domain CG11103 11-Aug-17 DroID_v2017_08 Drer\tm2d2 - Cele\C02F5.13 Xtro\tm2d2 Mmus\Tm2d2 Hsap\TM2D2 "viable,visible" trichogen cell FBgn0259480 EP-54 - http://flybase.org/reports/FBgn0259480 gene - - - EP-54 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "wing,wing vein,chaeta" FBgn0040385 CG12496 - http://flybase.org/reports/FBgn0040385 protein_coding_gene - - - "EG:BACH7M4.4, CG12496" IPR032057:Protein of unknown function DUF4799 CG12496 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,tormogen cell,mesothoracic tergum" FBgn0260063 2L3311 - http://flybase.org/reports/FBgn0260063 gene - - - 2L3311 - - 11-Aug-17 DroID_v2017_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0016954 tilK touch insensitive larva K http://flybase.org/reports/FBgn0016954 - gene - - - "line 147, tilK" - - 11-Aug-17 DroID_v2017_08 - - - - - - "touch sensitivity defective,recessive,visible,somatic clone,behavior defective" "macrochaeta,somatic clone,leg" FBgn0040725 CG13946 - http://flybase.org/reports/FBgn0040725 protein_coding_gene - - - CG13946 - CG13946 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0259431 C875 - http://flybase.org/reports/FBgn0259431 gene - - - C875 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0016707 Reg-12 Rhythmically expressed gene 12 http://flybase.org/reports/FBgn0016707 - gene - - - "Dreg-12, Reg-12" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | late , adult stage " head

FBgn0259338 C356 - http://flybase.org/reports/FBgn0259338 gene - - - C356 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing vein FBgn0038350 AOX4 Aldehyde oxidase 4 http://flybase.org/reports/FBgn0038350 protein_coding_gene "electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001041 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR006058 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR016166 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR016208 aldehyde oxidase activity ; GO:0004031 | inferred from sequence or structural similarity with AOX2, AOX3, AOX1 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 oxidoreductase activity, acting on the aldehyde or oxo group of donors ; GO:0016903 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 xanthine dehydrogenase activity ; GO:0004854 | inferred from biological aspect of ancestor with PANTHER:PTN000225632" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002346, InterPro:IPR002888, InterPro:IPR008274, InterPro:IPR016166, InterPro:IPR016208 cellular aldehyde metabolic process ; GO:0006081 | inferred from sequence or structural similarity with AOX2, AOX3, AOX1 xanthine catabolic process ; GO:0009115 | inferred from biological aspect of ancestor with PANTHER:PTN000225632" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 "CG18516, DmAO4, AOX4" "IPR000674:Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR002346:Molybdopterin dehydrogenase, FAD-binding, IPR002888:[2Fe-2S]-binding, IPR005107:CO dehydrogenase flavoprotein, C-terminal, IPR006058:2Fe-2S ferredoxin, iron-sulphur binding site, IPR008274:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding, IPR016166:FAD-binding, type 2, IPR016169:CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR016208:Aldehyde oxidase/xanthine dehydrogenase, IPR016167:FAD-binding, type 2, subdomain 1, IPR012675:Beta-grasp domain" CG18516 11-Aug-17 DroID_v2017_08 "Drer\aox6, Drer\xdh, Drer\aox5" - "Cele\gad-3, Cele\F55B11.1, Cele\F15E6.6" Xtro\xdh "Mmus\Aox3, Mmus\Aox2, Mmus\Aox4, Mmus\Aox1, Mmus\Xdh" "Hsap\AOX1, Hsap\XDH" FBgn0000961 fs(2)E8 female sterile (2) E8 http://flybase.org/reports/FBgn0000961 - gene - - - "fs2.8, fs(2)E8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0002223 l(3)68Ac lethal (3) 68Ac http://flybase.org/reports/FBgn0002223 - gene - - - "l(3)68Ac', l(3)C178, H, l(3)H, l(3)68Ac" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage,visible" "wing,leg" FBgn0002721 mesB messy B http://flybase.org/reports/FBgn0002721 - gene - - - "messy, 0303/02, mes-B, l(3)mes-4B, mesB" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,visible,partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "wing,trident,adult thorax & macrochaeta,adult abdomen,thorax,dorsal" FBgn0000878 fs(1)M76 female sterile (1) M76 http://flybase.org/reports/FBgn0000878 - gene - - - fs(1)M76 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0026317 Tsc1 Tsc1 http://flybase.org/reports/FBgn0026317 - protein_coding_gene protein kinase binding ; GO:0019901 | inferred from physical interaction with UniProtKB:Q8T9I6 kinase binding ; GO:0019900 | inferred from physical interaction with Tor protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VS24 "cholesterol homeostasis ; GO:0042632 |... genetic interaction with gig <> signal transduction ; GO:0007165 |... genetic interaction with Tor <> cellular response to chloroquine ; GO:1902350 |... mutant phenotype <> negative regulation of cell growth ; GO:0030308 | traceable author statement <> oogenesis ; GO:0048477 |... genetic interaction with Akt1 <> negative regulation of cell size ; GO:0045792 | traceable author statement <> response to nutrient ; GO:0007584 |... mutant phenotype <> lipid metabolic process ; GO:0006629 |... genetic interaction with gig <> cellular response to hypoxia ; GO:0071456 |... mutant phenotype <> regulation of cell growth ; GO:0001558 | traceable author statement <> negative regulation of cell growth ; GO:0030308 |... mutant phenotype <> negative regulation of cell growth ; GO:0030308 |... mutant phenotype inferred from genetic interaction with gig <> regulation of cell cycle ; GO:0051726 |... mutant phenotype <> TORC1 signaling ; GO:0038202 |... mutant phenotype <> regulation of cell proliferation ; GO:0042127 |... mutant phenotype <> positive regulation of autophagy ; GO:0010508 |... mutant phenotype <> negative regulation of cell proliferation ; GO:0008285 |... mutant phenotype <> regulation of timing of cell differentiation ; GO:0048505 |... mutant phenotype <> negative regulation of organ growth ; GO:0046621 |... mutant phenotype <> negative regulation of TOR signaling ; GO:0032007 |... biological aspect of ancestor with PANTHER:PTN000389117 <> trachea morphogenesis ; GO:0060439 |... mutant phenotype <> negative regulation of developmental growth ; GO:0048640 |... mutant phenotype <> negative regulation of cell growth ; GO:0030308 |... genetic interaction with UniProtKB:Q8INB9 <> insulin receptor signaling pathway ; GO:0008286 | non-traceable author statement <> negative regulation of organ growth ; GO:0046621 |... mutant phenotype inferred from genetic interaction with gig <> regulation of organ growth ; GO:0046620 | non-traceable author statement <> negative regulation of cell size ; GO:0045792 |... mutant phenotype inferred from genetic interaction with gig <> positive regulation of GTPase activity ; GO:0043547 |... direct assay <> larval midgut histolysis ; GO:0035069 |... genetic interaction with gig, Atg18a inferred from genetic interaction with gig, Atg1 <> regulation of cell cycle ; GO:0051726 | traceable author statement <> intestinal stem cell homeostasis ; GO:0036335 |... mutant phenotype <> enteroendocrine cell differentiation ; GO:0035883 |... mutant phenotype <> negative regulation of cell size ; GO:0045792 | non-traceable author statement <> regulation of terminal button organization ; GO:2000331 |... mutant phenotype <> determination of adult lifespan ; GO:0008340 |... mutant phenotype <> negative regulation of cell proliferation ; GO:0008285 |... genetic interaction with gig <> negative regulation of TOR signaling ; GO:0032007 |... genetic interaction with UniProtKB:Q8T9I6 <> regulation of reactive oxygen species metabolic process ; GO:2000377 |... mutant phenotype <> regulation of actin cytoskeleton organization ; GO:0032956 |... biological aspect of ancestor with PANTHER:PTN000389117 <> regulation of phosphorylation ; GO:0042325 |... direct assay <> negative regulation of insulin receptor signaling pathway ; GO:0046627 |... genetic interaction with InR <> negative regulation of cell size ; GO:0045792 |... mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay TSC1-TSC2 complex ; GO:0033596 | inferred from physical interaction with gig "TSC1, tsc1, dTsc1, dTSC1, dTSC, rocky, CG6147, Tsc1, TSC, dTSC-1, dtsc1" IPR007483:Hamartin CG6147 11-Aug-17 DroID_v2017_08 "Drer\tsc1a, Drer\tsc1b" - - - Mmus\Tsc1 Hsap\TSC1 "increased cell death,somatic clone,lethal - all die before end of larval stage,some die during larval stage,lethal,conditional,increased cell size,decreased cell growth,decreased cell death,visible,recessive,developmental rate defective,size defective,wild-type,cell autonomous,increased cell number,mitotic cell cycle defective,planar polarity defective,calorie restriction conditional,hyperplasia,long lived,viable" "eye disc,somatic clone,morphogenetic furrow,eye,ommatidium,intestinal stem cell,enteroendocrine cell,head capsule,cell autonomous,interommatidial bristle,rhabdomere | cell autonomous | somatic clone,eye photoreceptor cell,supernumerary,imaginal disc,wing margin bristle,rhabdomere,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,cone cell,ommatidial precursor cluster,melanotic mass,wing disc,eye disc & S phase | somatic clone,eye disc & mitotic cell cycle | somatic clone,adult head,eye-antennal disc,eye disc & S phase | ectopic | somatic clone,eye disc & mitotic cell cycle | ectopic | somatic clone,wing,fat body,chaeta,mesothoracic tergum,macrochaeta,ectopic,terminal tracheal cell,embryonic/larval tracheal system" FBgn0004875 enc encore http://flybase.org/reports/FBgn0004875 "FBgn0014170, FBgn0035466" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001374 oocyte dorsal/ventral axis specification ; GO:0007310 | traceable author statement karyosome formation ; GO:0030717 | traceable author statement oogenesis ; GO:0048477 | traceable author statement germ-line cyst formation ; GO:0048134 | traceable author statement regulation of pole plasm oskar mRNA localization ; GO:0007317 | traceable author statement germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype cystoblast division ; GO:0007282 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "fs(3)63F-64A, CG10847, BB129, enc, Enc" "IPR001374:R3H domain, IPR024771:SUZ domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG10847 11-Aug-17 DroID_v2017_08 "Drer\r3hdm1, Drer\arpp21" Scer\RBS1 Cele\ZK121.2 "Xtro\r3hdm2, Xtro\r3hdm1" "Mmus\R3hdm1, Mmus\Arpp21, Mmus\R3hdm2" "Hsap\R3HDM2, Hsap\ARPP21, Hsap\R3HDM1" " spermatogenesis && adult stage , adult stage | female && oogenesis stage , adult stage && oogenesis stage | mid , adult stage | female && oogenesis stage | , adult stage && oogenesis stage | stage S9 " " testis | restricted

, germarium region 1 && female germline stem cell

, oocyte | posterior

, germarium region 1 && cystocyte

, oocyte | anterior

" "female sterile,mitotic cell cycle defective,recessive,heat sensitive,cold sensitive,viable,lethal,maternal effect" "karyosome,dorsal appendage,follicle cell,egg chamber,chorion,ovary,nurse cell,oocyte nucleus,maternal effect,embryonic/larval posterior spiracle,filzkorper,anal pad,embryonic/first instar larval cuticle" FBgn0010247 Parp Poly-(ADP-ribose) polymerase http://flybase.org/reports/FBgn0010247 "FBgn0039975, FBgn0039998, FBgn0046268, FBgn0058411, FBan0040411" protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001510, InterPro:IPR008288 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR008288 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001510, InterPro:IPR008288 DNA ligase (ATP) activity ; GO:0003910 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 NAD+ ADP-ribosyltransferase activity ; GO:0003950 | inferred from direct assay histone binding ; GO:0042393 | inferred from physical interaction with His2A inferred from physical interaction with His2B inferred from physical interaction with His3 inferred from physical interaction with His4" "nucleolus organization ; GO:0007000 | inferred from mutant phenotype Cajal body organization ; GO:0030576 | inferred from mutant phenotype polytene chromosome puffing ; GO:0035079 | traceable author statement lagging strand elongation ; GO:0006273 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 protein ADP-ribosylation ; GO:0006471 | traceable author statement regulation of RNA splicing ; GO:0043484 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from expression pattern inferred from mutant phenotype rRNA transcription ; GO:0009303 | traceable author statement protein ADP-ribosylation ; GO:0006471 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement DNA ligation involved in DNA repair ; GO:0051103 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 maintenance of protein location in nucleus ; GO:0051457 | inferred from mutant phenotype metamorphosis ; GO:0007552 | traceable author statement positive regulation of protein localization to nucleus ; GO:1900182 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype chromosome organization ; GO:0051276 | traceable author statement dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from genetic interaction with orb" nuclear euchromatin ; GO:0005719 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome ; GO:0005700 | traceable author statement histone locus body ; GO:0035363 | inferred from direct assay Cajal body ; GO:0015030 | inferred from direct assay polytene chromosome puff ; GO:0005703 | traceable author statement nucleolus ; GO:0005730 | traceable author statement polytene chromosome puff ; GO:0005703 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay "PARP-1, PARP, dPARP, D.PARP, LD21673.3prime, CG17696, CG17718, CG17685, CG40411, BEST:LD21673, Parp, PARP1, dmparp, Dm.pARTa, parp, Parp1, dPARP1, dARTD1" "IPR001357:BRCT domain, IPR001510:Zinc finger, PARP-type, IPR004102:Poly(ADP-ribose) polymerase, regulatory domain, IPR008288:Poly [ADP-ribose] polymerase, IPR008893:WGR domain, IPR012317:Poly(ADP-ribose) polymerase, catalytic domain, IPR012982:PADR1 domain" CG40411 11-Aug-17 DroID_v2017_08 "Drer\parp4, Drer\parp2, Drer\parp1, Drer\parp3" - "Cele\parp-1, Cele\parp-2, Cele\tank-1" "Xtro\parp3, Xtro\parp2, Xtro\parp1" "Mmus\Parp2, Mmus\Parp3, Mmus\Parp1, Mmus\Parp4" "Hsap\PARP1, Hsap\PARP2, Hsap\PARP3, Hsap\PARP4" " embryonic stage | stage 14,15 , adult stage && oogenesis stage | stage S10 , embryonic stage | stage 16 , embryonic stage && pupal stage && adult stage , adult stage && oogenesis stage | stage S11,12 , embryonic stage " " embryonic central nervous system | vicinity of

, nurse cell

, anal plate

, oocyte

,

ubiquitous " "viable,immune response defective,heat stress response defective,aging defective,lethal - all die before end of larval stage,recessive,some die during larval stage,non-enhancer of variegation,non-suppressor of variegation,planar polarity defective,heat sensitive,visible,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "polytene chromosome puff,nucleolus,cephalopharyngeal skeleton,nucleus,polytene chromosome chromocenter,wing hair,heat sensitive,eye,adult abdomen,mesothoracic tergum,actin filament & embryonic epidermis | conditional ts,ommatidium,pigment cell,cone cell,ommatidial precursor cluster,photoreceptor cell R3,photoreceptor cell R4,eye disc,actin filament & retina,adult abdomen & cuticlearm.PS" FBgn0002926 ndl nudel http://flybase.org/reports/FBgn0002926 - protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR018114 serine-type peptidase activity ; GO:0008236 | non-traceable author statement peptidase activity ; GO:0008233 | traceable author statement serine-type peptidase activity ; GO:0008236 | traceable author statement serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "maternal specification of dorsal/ventral axis, oocyte, soma encoded ; GO:0007313 | inferred from electronic annotation with InterPro:IPR034381 Toll signaling pathway ; GO:0008063 | traceable author statement dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype protein processing ; GO:0016485 | inferred from genetic interaction with ea proteolysis ; GO:0006508 | inferred from sequence model proteolysis ; GO:0006508 | traceable author statement eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype egg activation ; GO:0007343 | inferred from mutant phenotype maternal specification of dorsal/ventral axis, oocyte, soma encoded ; GO:0007313 | traceable author statement oocyte dorsal/ventral axis specification ; GO:0007310 | non-traceable author statement" - "SP89, Ndl, nud, mel(3)5, mat(3)2, CG10129, ndl" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR015420:Peptidase S1A, nudel, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR034381:Nudel, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR033116:Serine proteases, trypsin family, serine active site" CG10129 11-Aug-17 DroID_v2017_08 Drer\prss56 - Cele\svh-1 "Xtro\LOC733551, Xtro\tmprss12" "Mmus\Prss56, Mmus\Tmprss12, Mmus\Acr" "Hsap\TMPRSS12, Hsap\PRSS56, Hsap\ACR" adult stage && oogenesis stage | stage S7-10 oocyte | anterior

"lethal,maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,partially,viable" "egg,maternal effect,chorion | maternal effect,blastoderm embryo,vitelline membrane,embryonic/first instar larval cuticle,embryonic epidermis,embryo,ventral" FBgn0002299 l(3)80Fj lethal (3) 80Fj http://flybase.org/reports/FBgn0002299 - gene - - - "lethal 1, l1, l(3)Lh1, l(3)80Fj, 80Fj" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0004636 Rap1 Rap1 GTPase http://flybase.org/reports/FBgn0004636 "FBgn0003190, FBgn0003207, FBgn0045818" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849 protein binding ; GO:0005515 | inferred from physical interaction with Rgl GTPase activity ; GO:0003924 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with cno, PDZ-GEF" "dorsal closure ; GO:0007391 | inferred from mutant phenotype ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement adherens junction assembly ; GO:0034333 | inferred from genetic interaction with PDZ-GEF germ-line stem cell population maintenance ; GO:0030718 | inferred from genetic interaction with PDZ-GEF establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from genetic interaction with PDZ-GEF positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype Rap protein signal transduction ; GO:0032486 | inferred from direct assay cell adhesion ; GO:0007155 | inferred from mutant phenotype Rap protein signal transduction ; GO:0032486 | inferred from genetic interaction with Epac substrate-dependent cell migration, cell extension ; GO:0006930 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from mutant phenotype regulation of JNK cascade ; GO:0046328 | NOT inferred from mutant phenotype inferred from genetic interaction with bsk regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay cell leading edge ; GO:0031252 | inferred from direct assay "Rap1, D-Rap1, Rap, Dras3, DRap1, DRap, ras 3, rap1, RasIII, ras3, RAP1, Dras62B, E(faf), l(3)R, l(3)62Bf, BEST:GH18528, Ras3, CG1956, C-ras3, R, EC3-7, FCG-C, P08645" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR020849:Small GTPase superfamily, Ras type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1956 11-Aug-17 DroID_v2017_08 "Drer\ralab, Drer\ralba, Drer\rras2, Drer\hrasa, Drer\rrad, Drer\diras1a, Drer\zgc:110699, Drer\diras2, Drer\rasl10a, Drer\mras, Drer\rem1, Drer\rras, Drer\rerglb, Drer\si:dkeyp-59c12.1, Drer\rit1, Drer\rhebl1, Drer\hrasb, Drer\rasl11b, Drer\rap1b, Drer\si:dkey-27j5.5, Drer\zgc:55558, Drer\rasl11a, Drer\kras, Drer\diras1b, Drer\si:ch73-116o1.2, Drer\gem, Drer\LOC103909873, Drer\rap2b, Drer\rasl12, Drer\rheb, Drer\rap1aa, Drer\rem2, Drer\nras, Drer\zgc:171704, Drer\rergla, Drer\rap1ab, Drer\zgc:153845, Drer\rsg1, Drer\ralbb, Drer\LOC100332969, Drer\rap2c, Drer\zgc:152698, Drer\zgc:114118, Drer\zgc:64022, Drer\rasd1, Drer\rap2ab, Drer\ralaa" "Scer\RAS1, Scer\RAS2, Scer\RSR1, Scer\RHB1, Scer\YPT53" "Cele\rap-2, Cele\rap-1, Cele\let-60, Cele\ras-1" "Xtro\LOC100485959, Xtro\diras1, Xtro\rasl10a, Xtro\rsg1, Xtro\rheb, Xtro\rala, Xtro\rras, Xtro\rap1a, Xtro\rrad, Xtro\rergl, Xtro\rem2, Xtro\ralb, Xtro\rap2b, Xtro\gem, Xtro\rap2a, Xtro\LOC733456, Xtro\rap2c, Xtro\diras2, Xtro\kras, Xtro\rerg, Xtro\rasl11b, Xtro\diras3, Xtro\rit1, Xtro\rem1, Xtro\ras-dva, Xtro\rasd1, Xtro\nras, Xtro\rhebl1, Xtro\rap1b, Xtro\rasd2, Xtro\hras" "Mmus\Rit1, Mmus\Rras, Mmus\Rap1a, Mmus\Rap2a, Mmus\Diras1, Mmus\Nras, Mmus\Rem2, Mmus\Rasl10a, Mmus\Rit2, Mmus\Rap2b, Mmus\Rap2c, Mmus\Rala, Mmus\Rsg1, Mmus\Rras2, Mmus\Mras, Mmus\Rhebl1, Mmus\Diras2, Mmus\Hras, Mmus\Eras, Mmus\Gm266, Mmus\Rasl12, Mmus\Rasl10b, Mmus\Rasd2, Mmus\Kras, Mmus\Rheb, Mmus\Rap1b, Mmus\Rerg, Mmus\Rasl11a, Mmus\Ralb, Mmus\Rasl11b, Mmus\Rem1, Mmus\Rrad, Mmus\Rasd1, Mmus\Gem, Mmus\Rergl" "Hsap\RASL11B, Hsap\RASD1, Hsap\RASL11A, Hsap\RERGL, Hsap\RAP1A, Hsap\RAP2C, Hsap\REM2, Hsap\RASL12, Hsap\RALB, Hsap\RRAD, Hsap\RRAS2, Hsap\RASD2, Hsap\HRAS, Hsap\RHEBL1, Hsap\RERG, Hsap\RRAS, Hsap\MRAS, Hsap\DIRAS3, Hsap\DIRAS2, Hsap\RAP2B, Hsap\GEM, Hsap\RIT1, Hsap\REM1, Hsap\RALA, Hsap\ERAS, Hsap\RASL10B, Hsap\KRAS, Hsap\NRAS, Hsap\RAP1B, Hsap\RASL10A, Hsap\RAP2A, Hsap\RHEB, Hsap\RIT2, Hsap\DIRAS1, Hsap\RSG1" " adult stage && oogenesis stage , larval stage | third instar , adult stage , embryonic stage " " oocyte

, genital disc

, thoracico-abdominal ganglion

, larval brain | restricted

, dorsal mesothoracic disc

, eye-antennal disc

, adult brain | resticted

" "viable,visible,recessive,lethal,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,wild-type,lethal - all die before end of larval stage,some die during larval stage,dominant,lethal - all die before end of pupal stage,some die during pupal stage,cell shape defective" "eye photoreceptor cell,eye,photoreceptor cell R7,ommatidium,rhabdomere | supernumerary,adherens junction | somatic clone,wing,somatic clone,macrophage,follicle cell,gastrula embryo,germline clone,maternal effect,ventral furrow,ventral nerve cord,embryonic head,mesoderm,embryonic/larval dorsal vessel,pole cell,dorsal closure embryo,embryonic/first instar larval cuticle,anterior,ventral,ovary,egg chamber,germarium,interfollicle cell,nurse cell,secondary pigment cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R8,retinal pigment cell,photoreceptor cell,cone cell,supernumerary,border follicle cell,glial cell,hemocyte" DRSC08686 E -0.948643252 -0.987534674 -2.516345909 -1.350297313 0.121309967 0.45782299 FBgn0028992 sds22 sds22 http://flybase.org/reports/FBgn0028992 protein_coding_gene - establishment or maintenance of polarity of larval imaginal disc epithelium ; GO:0016336 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from genetic interaction with Ras85D inferred from genetic interaction with scrib establishment or maintenance of polarity of follicular epithelium ; GO:0016334 | inferred from mutant phenotype protein phosphatase type 1 complex ; GO:0000164 | colocalizes_with inferred from direct assay "CT18355, CG5851, sds22, Sds22" "IPR025875:Leucine rich repeat 4, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG5851 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-267j14.7, Drer\LOC101885127, Drer\lrriq1, Drer\lrguk, Drer\drc3, Drer\lrrcc1, Drer\ppp1r7, Drer\cep97, Drer\lrrc61, Drer\si:ch211-103e16.5, Drer\lrrc9, Drer\lrrc6, Drer\lrrc23" "Scer\SDS22, Scer\NUD1" "Cele\B0524.3, Cele\C06A8.6, Cele\K10D2.8, Cele\sds-22" "Xtro\cep97, Xtro\dnal1, Xtro\ppp1r7, Xtro\lrrc56, Xtro\lrrc9, Xtro\lrrc23, Xtro\lrrc49, Xtro\lrrc6, Xtro\drc3, Xtro\lrrcc1" "Mmus\Lrrc56, Mmus\Cep97, Mmus\Ppp1r7, Mmus\Dnal1, Mmus\Cntrl, Mmus\Lrrc43, Mmus\Lrriq3, Mmus\Lrrc6, Mmus\Lrriq1, Mmus\Lrrc48, Mmus\Lrrc46, Mmus\Lrrc9, Mmus\Lrguk, Mmus\Lrrc49, Mmus\Lrrc23, Mmus\Lrrcc1, Mmus\Lrrc61" "Hsap\LRRIQ1, Hsap\LRRC49, Hsap\DNAL1, Hsap\CNTRL, Hsap\LRRC6, Hsap\LRRC56, Hsap\LRRC23, Hsap\LRGUK, Hsap\LRRIQ3, Hsap\PPP1R7, Hsap\LRRCC1, Hsap\LRRC46, Hsap\LRRC43, Hsap\CEP97, Hsap\LRRC61, Hsap\DRC3" "lethal,visible,somatic clone,partially lethal - majority die,some die during pupal stage" "wing disc,somatic clone,follicle cell,nurse cell,eye photoreceptor cell,eye,eye disc,trichogen cell,mesothoracic tergum" FBgn0010235 Klc Kinesin light chain http://flybase.org/reports/FBgn0010235 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W0K0 microtubule motor activity ; GO:0003777 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9GQF1 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from direct assay regulation of cell cycle ; GO:0051726 | inferred from direct assay dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from electronic annotation with InterPro:IPR002151 microtubule associated complex ; GO:0005875 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "KLC, kinesin, klc, DKLC, CG5433, Klc" "IPR002151:Kinesin light chain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR015792:Kinesin light chain repeat, IPR019734:Tetratricopeptide repeat, IPR011991:Winged helix-turn-helix DNA-binding domain" CG5433 11-Aug-17 DroID_v2017_08 "Drer\klc2, Drer\nphp3, Drer\cracr2b, Drer\klc4, Drer\klc1b, Drer\klc1a, Drer\appbp2, Drer\klc3, Drer\ttc19" Scer\PEA2 "Cele\klc-2, Cele\klc-1" "Xtro\ccdc157, Xtro\klc1, Xtro\nphp3, Xtro\ttc19, Xtro\appbp2" "Mmus\Acad11, Mmus\Klc3, Mmus\Klc4, Mmus\Nphp3, Mmus\Ttc19, Mmus\Appbp2, Mmus\Klc2, Mmus\Klc1" "Hsap\NPHP3, Hsap\TTC19, Hsap\ACAD11, Hsap\KLC1, Hsap\APPBP2, Hsap\KLC2, Hsap\KLC4, Hsap\KLC3, Hsap\APOPT1" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,paralytic,lethal - all die before end of larval stage,some die during larval stage,viable,visible" "dorsal appendage,germline clone,maternal effect,eye,somatic clone,embryonic/larval nervous system,trichogen cell" FBgn0004957 por porcupine http://flybase.org/reports/FBgn0004957 FBgn0003126 protein_coding_gene palmitoleoyltransferase activity ; GO:1990698 | inferred from sequence or structural similarity with UniProtKB:Q9JJJ7 Wnt-protein binding ; GO:0017147 | inferred from physical interaction with UniProtKB:P09615 inferred from physical interaction with UniProtKB:P28466 protein lipidation ; GO:0006497 | inferred from sequence or structural similarity with UniProtKB:Q9JJJ7 protein lipidation ; GO:0006497 | inferred from mutant phenotype protein palmitoylation ; GO:0018345 | inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with UniProtKB:Q9JJJ7 protein localization ; GO:0008104 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype protein palmitoleylation ; GO:0045234 | inferred from sequence or structural similarity with UniProtKB:Q9JJJ7 protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from mutant phenotype integral component of endoplasmic reticulum membrane ; GO:0030176 | non-traceable author statement endoplasmic reticulum ; GO:0005783 | inferred from direct assay "porc, Porc, dmPorc, 15175, poc, l(1)17Ac, CG6205, por" "IPR004299:Membrane bound O-acyl transferase, MBOAT" CG6205 11-Aug-17 DroID_v2017_08 "Drer\porcn, Drer\porcnl" Scer\ALE1 Cele\mom-1 Xtro\porcn Mmus\Porcn Hsap\PORCN " embryonic stage | early , embryonic stage -- adult stage " "lethal,recessive,rescuable maternal effect,germline clone,segment polarity phenotype,lethal - all die before end of larval stage,some die during larval stage,wild-type,visible,lethal - all die before end of pupal stage,some die during pupal stage,viable" "bouton,interommatidial bristle,embryonic/larval tracheal system,germline clone,embryonic/larval dorsal trunk,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,presumptive embryonic/larval central nervous system,denticle belt,embryonic head,embryonic/first instar larval cuticle,wing,wing & macrochaeta,antenna,leg,distal,unguis,supernumerary,sex comb,tergite,embryo,chaeta,trichogen cell" FBgn0005411 U2af50 U2 small nuclear riboprotein auxiliary factor 50 http://flybase.org/reports/FBgn0005411 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity poly-pyrimidine tract binding ; GO:0008187 | inferred from direct assay RNA binding ; GO:0003723 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with U2af38 pre-mRNA 3'-splice site binding ; GO:0030628 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 positive regulation of RNA export from nucleus ; GO:0046833 | inferred from mutant phenotype nuclear export ; GO:0051168 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000001557 mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nuclear speck ; GO:0016607 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 U2AF ; GO:0089701 | inferred from direct assay commitment complex ; GO:0000243 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000001557 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 "U2AF50, dUTAf[50], dU2AF[50], U2AF, DmU2AF[50], U2af, dU2AF50, DU2AF50, CG9998, l(1)9-21, l(1)14Ca, l(1)14Cc, 9-21, U2af50, U2AF 50, U2AF-50" "IPR000504:RNA recognition motif domain, IPR006529:U2 snRNP auxilliary factor, large subunit, splicing factor" CG9998 11-Aug-17 DroID_v2017_08 "Drer\u2af2a, Drer\u2af2b, Drer\uhmk1" "Scer\MUD2, Scer\RNA15" "Cele\uaf-1, Cele\Y82E9BR.2" Xtro\u2af2 "Mmus\Uhmk1, Mmus\U2af2" "Hsap\U2AF2, Hsap\UHMK1" embryonic stage -- adult stage "wild-type,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,visible" "embryonic/larval neuroblast,ganglion mother cell,wing" DRSC22867 IE -2.023704675 -2.179365099 -4.364589509 -4.207026992 0.605461637 0.85483062 FBgn0065521 l(2)SH1128 lethal (2) SH1128 http://flybase.net/reports/FBgn0065521.html gene l(2)SH2 1128 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0028948 CG15253 - http://flybase.org/reports/FBgn0028948 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026" - "BACR44L22.3, BG:BACR44L22.3, CG15253" "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG15253 11-Aug-17 DroID_v2017_08 "Drer\LOC797085, Drer\c6ast1, Drer\c6ast3, Drer\he1b, Drer\tnfaip6, Drer\LOC100003133, Drer\bmp1a, Drer\he1a, Drer\mep1b, Drer\mep1a.1, Drer\he2, Drer\c6ast4, Drer\npsn, Drer\si:ch73-40a17.3, Drer\tll1, Drer\bmp1b, Drer\mep1a.2, Drer\npsnl" - "Cele\nas-4, Cele\nas-12, Cele\nas-6, Cele\nas-2, Cele\nas-13, Cele\nas-39, Cele\nas-8, Cele\ZC116.3, Cele\Y19D10A.6, Cele\nas-1, Cele\nas-14, Cele\nas-7, Cele\nas-15" "Xtro\tll2, Xtro\LOC100489456, Xtro\bmp1, Xtro\uvs.2, Xtro\mep1a, Xtro\cubn, Xtro\LOC100492324, Xtro\tll1, Xtro\tnfaip6, Xtro\mep1b, Xtro\accs" "Mmus\Tll1, Mmus\Mep1a, Mmus\Adgrg6, Mmus\Cubn, Mmus\Tll2, Mmus\Mep1b, Mmus\Astl, Mmus\Tnfaip6, Mmus\Bmp1" "Hsap\ADGRG6, Hsap\MEP1B, Hsap\CUBN, Hsap\MEP1A, Hsap\TNFAIP6, Hsap\ASTL, Hsap\TLL2, Hsap\TLL1, Hsap\BMP1" "partially lethal - majority die,some die during pupal stage" DRSC01871 K -0.211719476 0.557519894 -0.341536916 -0.160900012 -1.740904126 0.10496823 FBgn0027296 temp tempura http://flybase.org/reports/FBgn0027296 FBgn0029609 protein_coding_gene Rab geranylgeranyltransferase activity ; GO:0004663 | contributes_to inferred from direct assay protein geranylgeranylation ; GO:0018344 | inferred from direct assay sensory organ development ; GO:0007423 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay Rab-protein geranylgeranyltransferase complex ; GO:0005968 | inferred from direct assay "temp, CG3073, l(1)G0144" "IPR002088:Protein prenyltransferase, alpha subunit" CG3073 11-Aug-17 DroID_v2017_08 Drer\ptar1 Scer\RAM2 "Cele\fnta-1, Cele\M57.2" - "Mmus\Ptar1, Mmus\Fnta" "Hsap\PTAR1, Hsap\FNTA" "lethal,some die during second instar larval stage,some die during third instar larval stage,visible,somatic clone,lethal - all die during third instar larval stage,recessive,female,viable" "mesothoracic tergum,somatic clone,chaeta,external sensory organ precursor cell I,tormogen cell,eo neuron,supernumerary" FBgn0040126 l(2)23CDb lethal (2) 23CDb http://flybase.org/reports/FBgn0040126 gene - - - l(2)23CDb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036925 schuy schumacher-levy http://flybase.org/reports/FBgn0036925 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG17736, schuy" - CG17736 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0000444 dg-a degenerated spermatheca http://flybase.org/reports/FBgn0000444 - gene - - - dg-a - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,good,fertile" spermathecal duct FBgn0027835 Dp1 Dodeca-satellite-binding protein 1 http://flybase.org/reports/FBgn0027835 "FBgn0027520, FBgn0027530, FBgn0046433, FBgn0061926" protein_coding_gene single-stranded DNA binding ; GO:0003697 | traceable author statement single-stranded DNA binding ; GO:0003697 | inferred from direct assay satellite DNA binding ; GO:0003696 | inferred from direct assay mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay chromosome segregation ; GO:0007059 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | inferred from direct assay chromosome condensation ; GO:0030261 | inferred from mutant phenotype heterochromatin assembly ; GO:0031507 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Dp1, ddp1, CG5170, DDP1, BcDNA:LD21677, BcDNA:LD21383, anon-WO0172774.168, anon-WO0118547.516" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG5170 11-Aug-17 DroID_v2017_08 "Drer\hdlbpa, Drer\hdlbpb, Drer\bicc2, Drer\bicc1b, Drer\bicc1a" "Scer\YLL032C, Scer\SCP160, Scer\MER1" "Cele\M01A10.1, Cele\C36E6.1, Cele\vgln-1, Cele\bcc-1" "Xtro\hdlbp, Xtro\bicc1" "Mmus\Hdlbp, Mmus\Bicc1, Mmus\Gm382" "Hsap\HDLBP, Hsap\BICC1" "lethal,recessive,partially,suppressor of variegation,dominant,female sterile,non-rescuable maternal effect,viable,non-suppressor of variegation,partially lethal - majority die" "ovary,ovariole,egg chamber,egg,maternal effect,mitotic anaphase | embryonic stage | maternal effect,mitotic telophase | embryonic stage | maternal effect,nucleus | embryonic stage | maternal effect" FBgn0013718 nuf nuclear fallout http://flybase.org/reports/FBgn0013718 "FBgn0013768, FBgn0015626, FBgn0024703, FBgn0044464, FBgn0052140, FBgn0053991, FBtr0075731, FBpp0075474, FBtr0075732, FBpp0075475, FBtr0075733, FBpp0075476, FBtr0075734, FBtr0075738, FBpp0075480, FBtr0075739, FBpp0075481, FBpp0089174" protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity "microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | non-traceable author statement sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" centrosome ; GO:0005813 | colocalizes_with inferred from direct assay microtubule organizing center ; GO:0005815 | colocalizes_with inferred from direct assay centrosome ; GO:0005813 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay "CG33991, CG7867, D2, Cy3-23, CG32140, anon-D2, EP3077, CIP-D2, nuf, Nuf, NUF, FIP3, Nuf1, Nuf2p" IPR019018:Rab-binding domain FIP-RBD CG33991 11-Aug-17 DroID_v2017_08 "Drer\rab11fip3, Drer\rab11fip4b, Drer\rab11fip4a" - Cele\rfip-1 "Xtro\rab11fip4, Xtro\rab11fip3, Xtro\ppfia1" "Mmus\Rab11fip3, Mmus\Rab11fip4" "Hsap\RAB11FIP4, Hsap\RAB11FIP3" embryonic stage | 0-3 hr " embryonic stage | cellular blastoderm , embryonic stage | 0-3 hr , embryonic stage | syncytial blastoderm " "visible,viable,fertile,neuroanatomy defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal,recessive,wild-type,partially lethal - majority die,some die during pupal stage" "scutellar bristle,ectopic,trichogen cell,socket,supernumerary,macrochaeta,intersegmental nerve,anterior fascicle & synapse | supernumerary,anterior fascicle & synapse,nucleus | embryonic stage,actin cytoskeleton | embryonic stage,cycle 11 embryo,maternal effect,cycle 12 embryo,cycle 13 embryo,cycle 14 embryo,mitotic telophase | maternal effect,cleavage furrow,wing,eye" FBgn0040147 l(1)G0478 lethal (1) G0478 http://flybase.org/reports/FBgn0040147 gene - - - l(1)G0478 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0002235 l(3)68Bb lethal (3) 68Bb http://flybase.org/reports/FBgn0002235 FBgn0002229 gene - - - "l(3)C46, B, l(3)B, l(3)68Bb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,female sterile" wing FBgn0082591 inferno inferno http://flybase.org/reports/FBgn0082591 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available inferno - - 11-Aug-17 DroID_v2017_08 - - - - - - "centrosome | embryonic stage | heat sensitive,microtubule | embryonic stage | heat sensitive" FBgn0001345 l(1)1Dc lethal (1) 1Dc http://flybase.org/reports/FBgn0001345 - gene - - - "JC45, l(1)1Dc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0002222 l(3)68Ab lethal (3) 68Ab http://flybase.org/reports/FBgn0002222 - gene - - - "l(3)C493, l(3)68Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,recessive,partially lethal - majority die,visible,lethal" eye FBgn0039555 mRpS22 mitochondrial ribosomal protein S22 http://flybase.org/reports/FBgn0039555 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D9 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AA313665 inferred from sequence or structural similarity with EMBL:AA463594 inferred from sequence or structural similarity with EMBL:AI004657 inferred from sequence or structural similarity with EMBL:W74092 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82650 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AA313665 inferred from sequence or structural similarity with EMBL:AA463594 inferred from sequence or structural similarity with EMBL:AI004657 inferred from sequence or structural similarity with EMBL:W74092 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D9 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82650 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82650 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with EMBL:AA313665 inferred from sequence or structural similarity with EMBL:AA463594 inferred from sequence or structural similarity with EMBL:AI004657 inferred from sequence or structural similarity with EMBL:W74092 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D9 "CG12261, MRP-S22, AAF56757, MrpS22, mRpS22" "IPR019374:Ribosomal protein S22, mitochondrial" CG12261 11-Aug-17 DroID_v2017_08 Drer\mrps22 - Cele\mrps-22 Xtro\mrps22 Mmus\Mrps22 Hsap\MRPS22 "viable,visible" trichogen cell FBgn0029117 Surf1 Surfeit 1 http://flybase.org/reports/FBgn0029117 protein_coding_gene - aerobic respiration ; GO:0009060 | inferred from sequence or structural similarity with UniProtKB:P53266 respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with UniProtKB:Q15526 phototaxis ; GO:0042331 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from sequence or structural similarity with UniProtKB:P53266 instar larval development ; GO:0002168 | inferred from mutant phenotype mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:P53266 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q15526 "CG9943, BcDNA:GH23574, Surf1, SUR1" IPR002994:Surfeit locus 1/Shy1 CG9943 11-Aug-17 DroID_v2017_08 Drer\surf1 Scer\SHY1 Cele\sft-1 Xtro\surf1 Mmus\Surf1 Hsap\SURF1 "lethal,partially,developmental rate defective,small body,phototaxis defective,locomotor behavior defective,long lived,neurophysiology defective,optomotor response defective,RU486 conditional,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval optic lobe,postsynaptic membrane,mitochondrion,ganglion mother cell,mesothoracic tergum" DRSC11295 I 0.125497666 -1.879791391 -0.409020076 -0.466199394 0.26700563 -0.145583445 FBgn0034697 GM130 Golgi matrix protein 130 kD http://flybase.org/reports/FBgn0034697 protein_coding_gene "Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab9 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab1, Rab30" "positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from genetic interaction with ecd Golgi vesicle transport ; GO:0048193 | inferred by curator from GO:0000137,GO:0017137" Golgi stack ; GO:0005795 | inferred from direct assay Golgi cis cisterna ; GO:0000137 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi cis cisterna ; GO:0000137 | "GM130, dGM130, dgm130, CG11061, GM-130" "IPR024858:Golgin subfamily A, IPR002395:HMW kininogen" CG11061 11-Aug-17 DroID_v2017_08 "Drer\golga2, Drer\si:ch211-208h16.4" - Cele\golg-2 "Xtro\fkbp15, Xtro\golga2" "Mmus\Golga2, Mmus\Gm13547" "Hsap\GOLGA6L1, Hsap\GOLGA6L2, Hsap\GOLGA6L9, Hsap\GOLGA6C, Hsap\GOLGA8N, Hsap\GOLGA8K, Hsap\GOLGA6L10, Hsap\GOLGA8A, Hsap\GOLGA6B, Hsap\GOLGA6L6, Hsap\GOLGA8J, Hsap\GOLGA6A, Hsap\GOLGA8B, Hsap\GOLGA8R, Hsap\GOLGA6L4, Hsap\GOLGA8M, Hsap\GOLGA8O, Hsap\GOLGA6L22, Hsap\GOLGA6L19, Hsap\GOLGA6D, Hsap\GOLGA2, Hsap\GOLGA8H" "neuroanatomy defective,viable,fertile,partially lethal - majority die,some die during pupal stage" "Golgi apparatus,dendritic arborizing neuron,dendrite,microtubule,dendritic branch point,class III dendritic arborizing neuron,Golgi apparatus19-12,dendritic arborizing neuron | larval stage,dendrite19-12,microtubule19-12,dendritic branch point19-12,class III dendritic arborizing neuron | larval stage" FBgn0062612 Mod(var)1309 Mod(var)1309 http://flybase.org/reports/FBgn0062612 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1309, Mod(var)1309" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0062584 Mod(var)177 Mod(var)177 http://flybase.org/reports/FBgn0062584 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "177, Mod(var)177" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant,viable" FBgn0016061 side sidestep http://flybase.org/reports/FBgn0016061 "FBgn0039515, FBgn0039516, FBgn0039517, FBgn0040611, FBgn0040612, FBgn0051062, FBgn0063636" protein_coding_gene - motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype - "CG31062, doe, Doe, CT33527, CT33528, CG13979, CG13975, CG13974, CG13973, CG12510, side, Side" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain" CG31062 11-Aug-17 DroID_v2017_08 Drer\nphs1 - - Xtro\nphs1 Mmus\Nphs1 "Hsap\VSIG10L, Hsap\PSG1, Hsap\NPHS1" "neuroanatomy defective,oxidative stress response defective,viable" "intersegmental nerve,segmental nerve,abdominal intersegmental nerve,abdominal segmental nerve,larval neuromuscular junction & abdominal dorsal acute muscle 1,larval neuromuscular junction & abdominal dorsal oblique muscle 1,larval neuromuscular junction & abdominal dorsal acute muscle 2,larval neuromuscular junction & abdominal dorsal oblique muscle 2,larval neuromuscular junction & abdominal lateral transverse muscle 1,larval neuromuscular junction & abdominal lateral transverse muscle 2,larval neuromuscular junction & abdominal lateral transverse muscle 3,larval neuromuscular junction & abdominal lateral transverse muscle 4,larval neuromuscular junction & abdominal ventral longitudinal muscle 1,larval neuromuscular junction & abdominal ventral longitudinal muscle 2,larval neuromuscular junction & abdominal ventral longitudinal muscle 3,larval neuromuscular junction & abdominal ventral longitudinal muscle 4,larval neuromuscular junction & abdominal ventral acute muscle 1,larval neuromuscular junction & abdominal ventral acute muscle 2,larval neuromuscular junction & abdominal ventral acute muscle 3,larval neuromuscular junction & abdominal ventral oblique muscle 4,larval neuromuscular junction & abdominal ventral oblique muscle 5,larval neuromuscular junction & abdominal ventral oblique muscle 6,growth cone & intersegmental nerve,A1-7 dorsal acute muscle 1,A1-7 dorsal acute muscle 2,A1-7 dorsal oblique muscle 1,A1-7 dorsal oblique muscle 2,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,A1-7 VL3/4 motor neuron,A1-7 VO2 motor neuron,A1-7 VO1 motor neuron,motor neuron" DRSC14523 I -1.615638577 2.154429037 0.291326972 0.401677121 -0.200807734 -0.565566288 FBgn0004034 y yellow http://flybase.org/reports/FBgn0004034 - protein_coding_gene - "melanin biosynthetic process from tyrosine ; GO:0006583 | traceable author statement regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from genetic interaction with Ask1 male courtship behavior, veined wing extension ; GO:0048065 | inferred from mutant phenotype cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype inferred from genetic interaction with e developmental pigmentation ; GO:0048066 | inferred from expression pattern developmental pigmentation ; GO:0048066 | traceable author statement male mating behavior ; GO:0060179 | inferred from mutant phenotype developmental pigmentation ; GO:0048066 | inferred from mutant phenotype melanin biosynthetic process ; GO:0042438 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cell hair ; GO:0070451 | inferred from direct assay "y, yellow, EG:125H10.2, CG3757, T6, Y" "IPR017996:Major royal jelly protein/protein yellow, IPR029846:Protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG3757 11-Aug-17 DroID_v2017_08 Drer\dpm3 - "Cele\T27A1.3, Cele\fbxa-76, Cele\F49E11.8, Cele\C24H12.1" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 " larval stage , pupal stage , embryonic stage | stage 15 , embryonic stage | stage 17 , adult stage , embryonic stage | stage 16 " " anal plate

, embryonic/larval esophagus

, cephalopharyngeal skeleton

" " pupal stage , adult stage , embryonic stage | stage 16 , embryonic stage " " epidermis

, cuticle

, embryonic/larval pharynx | anterior

, Keilin's organ

, abdominal segment 1--8

, cephalopharyngeal skeleton

, microchaeta

, denticle belt

" "body color defective,visible,recessive,viable,male,male fertile,mating defective,wild-type,reduced,eye color defective,heat sensitive,male sterile,dominant,small body,female,courtship behavior defective,fertile,behavior defective,cold sensitive,enhancer of variegation" "adult cuticle,wing vein,macrochaeta,wing hair,cuticle,wing,chaeta,wing blade,adult,adult abdomen,adult thorax,macrochaeta & adult thorax,macrochaeta & leg,leg & macrochaeta,antenna,adult cuticle & wing,male,unguis,adult epidermis,wing sensillum,prothoracic leg sensillum,mesothoracic leg sensillum,metathoracic leg sensillum,adult abdominal sensillum,adult thorax & macrochaeta,leg & external sensory organ,adult abdomen & macrochaeta,sex comb,arista,microchaeta,embryonic/larval mouth,cephalopharyngeal skeleton,mesothoracic bristle,macrochaeta & wing,macrochaeta & adult abdomen,pigment cell,larva,macrochaeta & thorax,macrochaeta & abdomen,head bristle,chaeta & adult thorax,cuticle & abdomen,wing & macrochaeta,mouth hooks,denticle belt,adult cuticle & adult abdomen | female,cold sensitive,scutum,leg,leg sensillum,adult thoracic sensillum,tibia,tarsal segment 2,tarsal segment 3,tarsal segment 4,antennal segment,metatarsus,pretarsus,analia,posterior compartment" FBgn0001569 l(1)20Ca lethal (1) 20Ca http://flybase.org/reports/FBgn0001569 - gene - - - "l(1)P-19, P19, 13E3, l(1)13E3, P-19, l(1)P19, l(1)D-19, l13E3, 33, l(1)20Ca" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,germline clone,rescuable maternal effect,partially" FBgn0003407 sie sieve http://flybase.org/reports/FBgn0003407 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sie - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,semidominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,recessive,non-suppressor of variegation,dominant" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0005011 Dipp Defective in phototaxis plasticity http://flybase.org/reports/FBgn0005011 - gene - - - Dipp - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,visual behavior defective" photoreceptor FBgn0003978 vls valois http://flybase.org/reports/FBgn0003978 FBgn0032841 protein_coding_gene - pole plasm assembly ; GO:0007315 | non-traceable author statement cellularization ; GO:0007349 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | traceable author statement embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype P granule ; GO:0043186 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay pole plasm ; GO:0045495 | inferred from direct assay "CG10728, CG107278, 38B.5, val, vls, Vls" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG10728 11-Aug-17 DroID_v2017_08 "Drer\wdr77, Drer\pex7" "Scer\RAD28, Scer\PEX7" Cele\swan-2 Xtro\wdr77 "Mmus\Pex7, Mmus\Wdr77" "Hsap\PEX7, Hsap\WDR77" "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,viable,germline clone,non-rescuable maternal effect,female sterile,grandchildless,male sterile,lethal,partially lethal - majority die,some die during pupal stage" "pole cell,maternal effect,pole plasm | maternal effect,egg,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,embryo,germline clone,posterior,stage 5 embryo,embryonic/first instar larval cuticle,pole granule,embryonic abdominal segment,karyosome,gamete,abdominal segment" FBgn0027552 CG10863 - http://flybase.org/reports/FBgn0027552 - protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" - "BcDNA:GH10614, CG10863, dm1/AKR2E3" "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG10863 11-Aug-17 DroID_v2017_08 "Drer\zgc:101765, Drer\akr1a1a, Drer\si:dkey-180p18.9, Drer\akr1b1, Drer\zgc:110782, Drer\zgc:110366, Drer\zgc:56622, Drer\akr1a1b, Drer\kcnab2a" "Scer\GCY1, Scer\AAD14, Scer\YDL124W, Scer\GRE3, Scer\YJR096W, Scer\ARA1, Scer\YPR1" "Cele\C01G5.5, Cele\Y39G8B.2, Cele\F53F1.2, Cele\C35D10.6, Cele\ZK1290.5, Cele\Y39G8B.1, Cele\K07C5.2, Cele\ZC443.1, Cele\C07D8.6, Cele\T08H10.1, Cele\C56G3.2, Cele\F53F1.3" "Xtro\akr1c2, Xtro\akr1c1, Xtro\akr1c8p, Xtro\akr1d1, Xtro\akr1a1, Xtro\akr1b1, Xtro\LOC548351" "Mmus\Akr1b3, Mmus\Akr1c14, Mmus\Akr1c13, Mmus\Akr1b10, Mmus\Akr1c6, Mmus\Akr1c21, Mmus\Akr1c18, Mmus\Akr1b8, Mmus\Kcnab1, Mmus\Akr1e1, Mmus\Akr1c20, Mmus\Akr1a1, Mmus\Akr1cl, Mmus\Akr1c19, Mmus\Akr1d1, Mmus\Akr1b7, Mmus\Akr1c12, Mmus\Kcnab2" "Hsap\AKR1C3, Hsap\AKR1C4, Hsap\AKR1C1, Hsap\AKR1B15, Hsap\AKR1E2, Hsap\AKR1B1, Hsap\KCNAB2, Hsap\AKR1C2, Hsap\AKR1A1, Hsap\AKR1D1, Hsap\AKR1B10" "viable,visible" mesothoracic tergum FBgn0011096 l(1)Q56 lethal (1) Q56 http://flybase.org/reports/FBgn0011096 FBgn0010210 gene - - - l(1)Q56 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0002269 l(3)69Ba lethal (3) 69Ba http://flybase.org/reports/FBgn0002269 - gene - - - "rsg31, l(3)rsg31, l(3)69Ba" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0010073 Metatarsi-irregular Metatarsi irregular http://flybase.org/reports/FBgn0010073 - gene - - - "Metatarsi-irregular, Met" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,chemical resistant" "tarsal segment 1 & joint,tarsal segment 2 & joint,leg sensillum,eye" FBgn0001455 l(1)7Di lethal (1) 7Di http://flybase.org/reports/FBgn0001455 - gene - - - l(1)7Di - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0002210 l(3)67BDh lethal (3) 67BDh http://flybase.org/reports/FBgn0002210 - gene - - - l(3)67BDh - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal,some die during immature adult stage,recessive" FBgn0025864 Crag Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein http://flybase.org/reports/FBgn0025864 - protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab11 calmodulin binding ; GO:0005516 | inferred from direct assay calmodulin binding ; GO:0005516 | inferred from physical interaction with Cam Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from direct assay basement membrane assembly ; GO:0070831 | inferred from mutant phenotype activation of GTPase activity ; GO:0090630 | inferred from direct assay asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype positive regulation of Golgi to plasma membrane protein transport ; GO:0042998 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype regulation of Rab protein signal transduction ; GO:0032483 | inferred from direct assay positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype basal protein localization ; GO:0045175 | inferred from mutant phenotype cell cortex ; GO:0005938 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CRAG, CG12737, Crag, CJ" "IPR001194:DENN domain, IPR005112:dDENN domain, IPR005113:uDENN domain, IPR023341:MABP domain" CG12737 11-Aug-17 DroID_v2017_08 "Drer\dennd4a, Drer\dennd4b, Drer\dennd5b, Drer\dennd4c, Drer\dennd5a" - "Cele\lst-6, Cele\denn-4" "Xtro\dennd4c, Xtro\dennd4b, Xtro\dennd4a" "Mmus\Dennd5a, Mmus\Dennd4a, Mmus\Dennd4c, Mmus\Dennd2c, Mmus\Dennd4b" "Hsap\DENND4A, Hsap\DENND5A, Hsap\DENND2C, Hsap\DENND5B, Hsap\DENND4C, Hsap\DENND4B" adult stage "neurophysiology defective,somatic clone,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal - all die before end of larval stage,some die during third instar larval stage,progressive,conditional,some die during larval stage,visible,body color defective,partially lethal - majority die,some die during pupal stage" "rhabdomere | progressive | somatic clone | conditional,trans-Golgi network | somatic clone,follicle cell,somatic clone,mesothoracic tergum" FBgn0027095 Manf Mesencephalic astrocyte-derived neurotrophic factor http://flybase.org/reports/FBgn0027095 FBgn0026289 protein_coding_gene - "dopaminergic neuron differentiation ; GO:0071542 | inferred from biological aspect of ancestor with PANTHER:PTN000312771 synaptic transmission, dopaminergic ; GO:0001963 | inferred from mutant phenotype neuron projection development ; GO:0031175 | inferred from mutant phenotype dopamine metabolic process ; GO:0042417 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype" endomembrane system ; GO:0012505 | inferred from direct assay extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000312771 extracellular region ; GO:0005576 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "anon-EST:ParkEST188, CG7013, DmMANF, ARP-like, Manf, DmManf, MANF, manf" "IPR018247:EF-Hand 1, calcium-binding site, IPR019345:Armet protein, IPR003034:SAP domain" CG7013 11-Aug-17 DroID_v2017_08 "Drer\manf, Drer\cdnf" - Cele\Y54G2A.23 Xtro\manf "Mmus\Manf, Mmus\Cdnf" "Hsap\CDNF, Hsap\MANF" "lethal,recessive,lethal - all die during first instar larval stage,locomotor behavior defective,maternal effect,increased cell death,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" "neurite & dopaminergic neuron | larval stage,ventral nerve cord,maternal effect,embryonic/larval cell body glial cell,neuropil,embryonic/first instar larval cuticle" FBgn0010314 Cks30A Cyclin-dependent kinase subunit 30A http://flybase.org/reports/FBgn0010314 FBgn0003235 protein_coding_gene histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 protein kinase binding ; GO:0019901 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 cyclin-dependent protein serine/threonine kinase activator activity ; GO:0061575 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 protein binding ; GO:0005515 | inferred from physical interaction with Cdk1 inferred from physical interaction with Cdk2 ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 "female meiotic division ; GO:0007143 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype histoblast morphogenesis ; GO:0007488 | inferred from mutant phenotype anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 spindle assembly involved in female meiosis I ; GO:0007057 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 female meiosis I ; GO:0007144 | inferred from mutant phenotype" SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000602176 "Cks, U40077, Cdi2, CDI2, cks30A, rem, fs(2)rem, cdi2, DmCks1, CG3738, Cks30A, cks" "IPR000789:Cyclin-dependent kinase, regulatory subunit" CG3738 11-Aug-17 DroID_v2017_08 "Drer\cks2, Drer\cks1b, Drer\zgc:86839" Scer\CKS1 "Cele\cks-1, Cele\Y71G12B.27" "Xtro\cks2, Xtro\cks1b" "Mmus\Cks1brt, Mmus\Cks2, Mmus\Cks1b" "Hsap\CKS1B, Hsap\CKS2" "viable,male fertile,lethal,maternal effect,mitotic cell cycle defective,meiotic cell cycle defective,female limited,female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,female,partially lethal - majority die,some die during pupal stage" "aster & oocyte,larval cuticle & larval abdomen,embryonic/first instar larval cuticle,aster,spindle pole centrosome,spindle,spindle & oocyte" FBgn0003891 tud tudor http://flybase.org/reports/FBgn0003891 - protein_coding_gene - pole plasm assembly ; GO:0007315 | traceable author statement P granule organization ; GO:0030719 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | inferred from mutant phenotype germ cell development ; GO:0007281 | traceable author statement pole cell development ; GO:0007277 | inferred from mutant phenotype mitochondrial rRNA export from mitochondrion ; GO:0019090 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | traceable author statement P granule ; GO:0043186 | inferred from direct assay P granule ; GO:0043186 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay pole plasm ; GO:0045495 | inferred from direct assay mitochondrion ; GO:0005739 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "tud, tu, CG9450, TUD, Tud, R5_2R:17070527..17070890, Tudor, tudor" IPR002999:Tudor domain CG9450 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-93d12.1, Drer\si:ch211-189e2.3, Drer\tdrd6, Drer\tdrd1, Drer\rnf17" - - - "Mmus\Rnf17, Mmus\Tdrd6, Mmus\Tdrd1" "Hsap\TDRD1, Hsap\TDRD6, Hsap\RNF17, Hsap\TDRD15" " adult stage && oogenesis stage | stage S10-14 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-3 " " follicle cell | posterior

, germarium

, ovariole

" " oogenesis stage | stage S7-9 , embryonic stage , adult stage && oogenesis stage | stage S10 " " oocyte

,

, vitelline membrane

" "grandchildless,male fertile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal,male sterile,germline clone,non-rescuable maternal effect,female sterile,sterile,partially,viable" "pole cell,maternal effect,germline cell,embryonic abdominal segment,gonad,P granule | maternal effect,P granule | maternal effectPF1),spermatozoon,pole granule,abdominal segment,egg,P granulePF1),embryo,germline clone,posterior,pole plasm | maternal effect,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11" FBgn0003388 shd shade http://flybase.org/reports/FBgn0003388 FBgn0036432 protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 ecdysone 20-monooxygenase activity ; GO:0004501 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 midgut development ; GO:0007494 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype pupation ; GO:0035074 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype ecdysteroid biosynthetic process ; GO:0045456 | inferred from direct assay inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay "Cyp314a1, 314a1, CG13478, shd, CYP314A1, shade, cyp314a1" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG13478 11-Aug-17 DroID_v2017_08 "Drer\cyp27a1.2, Drer\zgc:136333, Drer\si:ch211-113j14.1, Drer\cyp24a1, Drer\cyp27a1.4, Drer\cyp11a2, Drer\si:dkey-91i10.3, Drer\cyp27a7, Drer\cyp27b1, Drer\cyp11c1, Drer\cyp27c1" Scer\DIT2 "Cele\cyp-35B3, Cele\cyp-33D1, Cele\cyp-44A1" "Xtro\cyp27b1, Xtro\cyp24a1, Xtro\LOC100145331, Xtro\cyp11a1, Xtro\cyp27a1, Xtro\cyp27c1" "Mmus\Cyp11b2, Mmus\Cyp11b1, Mmus\Cyp11a1, Mmus\Cyp27a1, Mmus\Cyp24a1, Mmus\Cyp27b1" "Hsap\CYP11B1, Hsap\CYP11B2, Hsap\CYP27B1, Hsap\CYP27C1, Hsap\CYP27A1, Hsap\CYP11A1, Hsap\CYP24A1" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,female sterile" "presumptive embryonic/larval central nervous system,dorsal closure embryo,embryonic ventral epidermis,ventral nerve cord,embryonic/larval midgut,embryonic/larval foregut,embryonic/larval hindgut,commissure,glial cell,midline glial cell,ectopic,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,embryonic head,embryonic/larval midgut primordium,embryonic dorsal epidermis,epicuticle,embryonic/larval cuticle,egg chamber,border follicle cell,somatic clone,midgut constriction,embryo,embryonic/larval tracheal system" FBgn0005355 Su(fu) Suppressor of fused http://flybase.org/reports/FBgn0005355 FBgn0003562 protein_coding_gene transcription factor binding ; GO:0008134 | inferred from physical interaction with ci negative regulation of smoothened signaling pathway ; GO:0045879 | non-traceable author statement negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from genetic interaction with cos negative regulation of sequence-specific DNA binding transcription factor activity ; GO:0043433 | inferred from genetic interaction with cos cytoplasmic sequestering of transcription factor ; GO:0042994 | inferred from mutant phenotype negative regulation of protein binding ; GO:0032091 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from physical interaction with fu inferred from physical interaction with ci cytoplasm ; GO:0005737 | inferred from direct assay Hedgehog signaling complex ; GO:0035301 | colocalizes_with inferred from physical interaction with fu inferred from physical interaction with ci "Su(fu), su(fu), Su(Fu), SuFu, Sufu, CG6054, SUFU, SU(FU), sufu, dSufu" "IPR007768:Suppressor of fused, IPR016591:Suppressor of fused, eukaryotic, IPR024314:Suppressor of fused C-terminal, IPR020941:Suppressor of fused-like domain" CG6054 11-Aug-17 DroID_v2017_08 Drer\sufu - - Xtro\sufu Mmus\Sufu Hsap\SUFU " adult stage | female , embryonic stage "

ubiquitous "viable,wild-type,lethal - all die before end of pupal stage,some die during pupal stage" "egg chamber,wing vein,sensillum campaniformium of dorsal radius,costal vein,axillary vein,wing margin,prothoracic leg,sex comb,supernumerary,metathoracic leg,antenna,wing disc" FBgn0266450 Kr-h1 Kruppel homolog 1 http://flybase.org/reports/FBgn0266450 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with Kr" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with Kr response to ecdysone ; GO:0035075 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype negative regulation of neuron projection development ; GO:0010977 | inferred from genetic interaction with babo negative regulation of compound eye photoreceptor development ; GO:0045316 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with Kr "Kr-h1, Kr-h, CG9167, l(2)10642, P381, Pow, 44/11, Kr h, l(2)05208, CG18783, Kr-H1, CG45074" IPR013087:Zinc finger C2H2-type CG45074 11-Aug-17 DroID_v2017_08 "Drer\LOC568955, Drer\zbtb16a, Drer\zgc:113102, Drer\gfi1aa, Drer\gtf3aa, Drer\zbtb49, Drer\si:dkey-262g12.7, Drer\LOC101882721, Drer\gfi1ab, Drer\znf384l, Drer\zbtb24, Drer\zbtb7a, Drer\znf76, Drer\znf668, Drer\patz1" "Scer\CMR3, Scer\AZF1, Scer\PZF1, Scer\YPR015C" "Cele\F21A9.2, Cele\M03D4.4, Cele\zfp-2, Cele\pqm-1, Cele\fezf-1, Cele\odd-2, Cele\lin-29, Cele\F10B5.3" "Xtro\zbtb7c, Xtro\patz1, Xtro\zfx, Xtro\hic1, Xtro\zbtb11, Xtro\gzf1, Xtro\zfp1" "Mmus\Zfp131, Mmus\Zfp975, Mmus\Patz1, Mmus\Zfp940, Mmus\Zfp69, Mmus\Bcl6b, Mmus\Zfp418, Mmus\Zbtb7b, Mmus\Gfi1b, Mmus\Gtf3a, Mmus\Zbtb7a, Mmus\Gfi1, Mmus\Zfp1, Mmus\Zfp316, Mmus\Zfp345, Mmus\Zim1, Mmus\Zbtb41, Mmus\Zfp651, Mmus\Gzf1, Mmus\Zfp263, Mmus\Zfp825, Mmus\Zfp568, Mmus\Zbtb24, Mmus\Zscan25, Mmus\Zbtb16, Mmus\Zbtb7c, Mmus\Zfp358, Mmus\Zbtb17, Mmus\Mzf1, Mmus\Bcl6, Mmus\Zbtb49, Mmus\Zfp672, Mmus\Zfp637" "Hsap\ZBTB17, Hsap\ZNF652, Hsap\ZNF32, Hsap\ZNF658, Hsap\REPIN1, Hsap\ZBTB11, Hsap\ZNF417, Hsap\PATZ1, Hsap\ZNF835, Hsap\ZBTB24, Hsap\ZSCAN10, Hsap\ZBTB41, Hsap\ZNF131, Hsap\ZNF467, Hsap\BCL6B, Hsap\ZNF358, Hsap\ZBTB49, Hsap\ZBTB47, Hsap\ZNF132, Hsap\ZNF143, Hsap\ZNF418, Hsap\ZFP1, Hsap\ZNF530, Hsap\GFI1B, Hsap\ZNF169, Hsap\ZBTB7C, Hsap\ZBTB7B, Hsap\GLI4, Hsap\ZNF569, Hsap\BCL11B, Hsap\ZBTB16, Hsap\ZBTB7A, Hsap\GFI1, Hsap\ZBTB48, Hsap\GTF3A" " larval stage | third instar , larval stage | first instar , embryonic stage , embryonic stage -- adult stage , embryonic stage | stage 5-8 , embryonic stage | 20-24 hr , larval stage | second instar , prepupal stage | <=6-8 hr , adult stage , prepupal stage | 6-8 hr , embryonic stage | mid-late " organism

FBgn0004373 fwd four wheel drive http://flybase.org/reports/FBgn0004373 "FBgn0035129, FBgn0062139" protein_coding_gene 1-phosphatidylinositol 4-kinase activity ; GO:0004430 | inferred from biological aspect of ancestor with PANTHER:PTN000005893 1-phosphatidylinositol 4-kinase activity ; GO:0004430 | non-traceable author statement phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR015433 phosphatidylinositol-mediated signaling ; GO:0048015 | inferred from electronic annotation with InterPro:IPR015433 male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype phosphorylation ; GO:0016310 | non-traceable author statement meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype male germline ring canal formation ; GO:0030726 | inferred from mutant phenotype spermatocyte division ; GO:0048137 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay "CG7004, PI4K, anon-WO0118547.259, fwd, Fwd" "IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR011009:Protein kinase-like domain, IPR015433:Phosphatidylinositol kinase" CG7004 11-Aug-17 DroID_v2017_08 Drer\pi4kb Scer\PIK1 Cele\pifk-1 Xtro\pi4kb Mmus\Pi4kb Hsap\PI4KB "viable,fertile,long lived,meiotic cell cycle defective,male,male sterile,cytokinesis defective,female fertile,recessive,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,visible,lethal" "spermatid & nucleus7C),spermatid,spermatid axoneme,Nebenkern derivative,spermatozoon,Golgi apparatus,spermatid & nucleusemc-E12),Nebenkern,secondary spermatocyte,spindle & meiotic telophase I | male7C),contractile ring & meiotic telophase I | male7C),spindle & meiotic telophase II | male7C),contractile ring & meiotic telophase II | male7C),spermatid & nucleus | supernumerary,wing hair,supernumerary,wing blade" DRSC08580 IE 1.838953122 1.895909477 2.288742922 -0.422595564 0.221880936 0.743956749 FBgn0030089 AP-1gamma "Adaptor Protein complex 1, gamma subunit" http://flybase.org/reports/FBgn0030089 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from electronic annotation with InterPro:IPR017107 protein transporter activity ; GO:0008565 | inferred by curator from GO:0035976 "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR008152 secretory granule organization ; GO:0033363 | inferred from mutant phenotype vesicle coating ; GO:0006901 | traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement cargo loading into clathrin-coated vesicle ; GO:0035652 | inferred from mutant phenotype synaptic vesicle coating ; GO:0016183 | traceable author statement" secretory granule ; GO:0030141 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay clathrin-coated vesicle ; GO:0030136 | inferred from direct assay synaptic vesicle ; GO:0008021 | traceable author statement AP-1 adaptor complex ; GO:0030121 | inferred from mutant phenotype inferred from physical interaction with AP-1μ coated vesicle ; GO:0030135 | traceable author statement "cg9113, CG9113, gamma, AP-1[gamma], AP-1gamma, AP-1, gamma-Ada, apl4, AP1gamma, dgamma, AP1gamma1, Ap-1, AP-1 gamma" "IPR002553:Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR008152:Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain, IPR008153:Gamma-adaptin ear (GAE) domain, IPR011989:Armadillo-like helical, IPR013041:Coatomer/clathrin adaptor appendage, Ig-like subdomain, IPR016024:Armadillo-type fold, IPR017107:Adaptor protein complex AP-1, gamma subunit" CG9113 11-Aug-17 DroID_v2017_08 "Drer\ap1g1, Drer\ap4e1, Drer\ap1g2" Scer\APL4 Cele\apg-1 "Xtro\ap1g1, Xtro\ap4e1" "Mmus\Ap4e1, Mmus\Ap1g2, Mmus\Ap1g1" "Hsap\AP1G2, Hsap\AP4E1, Hsap\AP1G1" "lethal - all die before end of pupal stage,some die during pupal stage" "tormogen cell,supernumerary,embryonic/larval salivary gland | third instar larval stage,secretory granuleAB1,trans-Golgi networkAB1,eye,ommatidium" FBgn0017551 Rca1 Regulator of cyclin A1 http://flybase.org/reports/FBgn0017551 - protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of meiotic nuclear division ; GO:0045835 | inferred from biological aspect of ancestor with PANTHER:PTN000398158 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle ; GO:0051436 | inferred from biological aspect of ancestor with PANTHER:PTN000398158 eye-antennal disc morphogenesis ; GO:0007455 | non-traceable author statement negative regulation of ubiquitin protein ligase activity ; GO:1904667 | inferred from mutant phenotype inferred from genetic interaction with fzr negative regulation of ubiquitin protein ligase activity ; GO:1904667 | inferred from mutant phenotype SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model nucleus ; GO:0005634 | inferred from direct assay "152549_at, rca1, CG10800, P3300, S(rux)2A, l(2)03300, Rca1, RCA1, CLD4, Emi1, FBXO5" - CG10800 11-Aug-17 DroID_v2017_08 "Drer\fbxo5, Drer\fbxo43" - - "Xtro\fbxo43, Xtro\fbxo5" "Mmus\Fbxo43, Mmus\Fbxo5" "Hsap\FBXO43, Hsap\FBXO5" " embryonic stage | stage >=8 , embryonic stage | early , embryonic stage | stage 8-9 , embryonic stage | stage >=13 " " anterior midgut proper primordium

,

ubiquitous , posterior midgut proper primordium

, mesoderm

, embryonic nervous system

" "viable,fertile,partially lethal - majority die,lethal,recessive,mitotic cell cycle defective,somatic clone,decreased cell number,lethal - all die before end of pupal stage,some die during pupal stage,increased cell number,neuroanatomy defective,visible" "ganglion mother cell GMC4-2a,RP2sib neuron,ganglion mother cell,pCC neuron,aCC neuron,precursor,U neuron,embryonic pericardial cell,abdominal segment 2 & cardioblast,abdominal segment 3 & cardioblast,abdominal segment 4 & cardioblast,abdominal segment 5 & cardioblast,abdominal segment 6 & cardioblast,abdominal segment 7 & cardioblast,ganglion mother cell GMC1-1a,EL neuron,eye,wing disc,somatic clone,nucleus | somatic clone,cardioblast,eye disc posterior to the morphogenetic furrow,embryonic/larval neuroblast,chaeta" DRSC03407 IEK -0.233954906 -1.619027019 1.697755759 -2.828038056 4.390766491 3.394545227 FBgn0011205 fbl fumble http://flybase.org/reports/FBgn0011205 "FBgn0052429, FBgn0036981" protein_coding_gene pantothenate kinase activity ; GO:0004594 | inferred from electronic annotation with InterPro:IPR004567 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR004567 pantothenate kinase activity ; GO:0004594 | inferred from sequence alignment with MGI:MGI:1921700 inferred from sequence alignment with SGD:S000002939 coenzyme A biosynthetic process ; GO:0015937 | inferred from electronic annotation with InterPro:IPR004567 spermatogenesis ; GO:0007283 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype membrane organization ; GO:0061024 | inferred from expression pattern cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype regulation of cytokinesis ; GO:0032465 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype coenzyme A biosynthetic process ; GO:0015937 | inferred from sequence alignment with SGD:S000002939 spindle ; GO:0005819 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG5725, fbl, dPANK, PANK, dPANK/Fbl, Fbl, dPanK" IPR004567:Type II pantothenate kinase CG5725 11-Aug-17 DroID_v2017_08 "Drer\pank1b, Drer\pank1a, Drer\pank4, Drer\pank2" Scer\CAB1 "Cele\C17H1.13, Cele\pnk-1, Cele\pnk-4, Cele\C17H1.8" "Xtro\pank4, Xtro\gas8, Xtro\pank3, Xtro\pank1, Xtro\pank2" "Mmus\Pank4, Mmus\Pank3, Mmus\Gas8, Mmus\Pank2, Mmus\Pank1" "Hsap\PANK1, Hsap\PANK3, Hsap\PANK4, Hsap\GAS8, Hsap\PANK2" "meiotic cell cycle defective,female sterile,recessive,behavior defective,female,uncoordinated,cytokinesis defective,male,male sterile,partially lethal,locomotor behavior defective,flightless,flight defective,short lived,visible,chemical sensitive,radiation sensitive,increased cell death,sterile,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,wild-type,oxidative stress response defective,locomotor rhythm defective,visual behavior defective" "spermatid,spermatocyte & spindle,spermatocyte & aster,Nebenkern derivative,spermatid & nucleus,spermatocyte & centrosome,testis,Nebenkern,wing,adult brain,embryonic/larval brain,ovary,dorsal appendage,maternal effect,egg,anterior crossvein,posterior crossvein,retina,onion stage spermatid,mitotic cell cycle,mitotic metaphase,anaphase & condensed nuclear chromosome,macrochaeta,ectopic" FBgn0062585 Mod(var)1683 Mod(var)1683 http://flybase.org/reports/FBgn0062585 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1683, Mod(var)1683" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0020238 14-3-3epsilon 14-3-3epsilon http://flybase.org/reports/FBgn0020238 "FBgn0011329, FBgn0016739, FBgn0016743, FBgn0046456, FBgn0051196, FBgn0064146, FBgn0066007" protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from electronic annotation with InterPro:IPR000308 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q45VV3 phosphoserine binding ; GO:0050815 | inferred from physical interaction with PlexA protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with 14-3-3ζ "pole cell migration ; GO:0007280 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D DNA damage checkpoint ; GO:0000077 | traceable author statement response to UV ; GO:0009411 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | traceable author statement oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs regulation of growth ; GO:0040008 | inferred from genetic interaction with foxo axon guidance ; GO:0007411 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap response to radiation ; GO:0009314 | traceable author statement germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype mitotic cell cycle checkpoint ; GO:0007093 | traceable author statement positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of growth ; GO:0045927 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay germline ring canal ; GO:0045172 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay "14-3-3epsilon, PAR5, 14-3-3, par-5, Par-5, D14-3-3epsilon, D14-3-3e, 14-3-3-e, 14-3-3e, EK3-5, CT24092, d14-3-3epsilon, SR3-9, l(3)j2B10, Su(Raf)3B, CG31196, anon-WO02059370.52, anon-WO0172774.141, eps, PAR-5, 14-3-3-epsilon, 14-3-3 epsilon, 143E_DROME, 14-3-30epsilon, 14-3-3omicron, 1433epsilon, 14-3-3EPSILON, 14.3.3 epsilon, e-14-3-3" "IPR000308:14-3-3 protein, IPR023409:14-3-3 protein, conserved site, IPR023410:14-3-3 domain" CG31196 11-Aug-17 DroID_v2017_08 "Drer\ywhae1, Drer\ywhaz, Drer\ywhabb, Drer\ywhag2, Drer\ywhae2, Drer\ywhah, Drer\ywhag1, Drer\ywhaba, Drer\ywhaqa, Drer\ywhaqb, Drer\ywhabl" "Scer\BMH2, Scer\BMH1" "Cele\ftt-2, Cele\par-5, Cele\M117.3" "Xtro\ywhah, Xtro\ywhaz, Xtro\ywhae, Xtro\ywhag, Xtro\ywhab, Xtro\ywhaq" "Mmus\Ywhab, Mmus\Ywhae, Mmus\Ywhaz, Mmus\Sfn, Mmus\Ywhaq, Mmus\Ywhag, Mmus\Ywhah" "Hsap\YWHAE, Hsap\SFN, Hsap\YWHAQ, Hsap\YWHAH, Hsap\YWHAB, Hsap\YWHAZ, Hsap\YWHAG" " embryonic stage | stage 9-10 , embryonic stage | stage 7,8 , adult stage , embryonic stage | syncytial blastoderm , embryonic stage " " ventral nerve cord primordium

, cephalic furrow

, germarium

, ring canal

, embryonic peripheral nervous system

, amnioproctodeal invagination

, embryonic central nervous system

, ventral midline

, dorsal ectoderm

, posterior transverse furrow

, anterior transverse furrow

" "neuroanatomy defective,lethal,lethal - all die before end of embryonic stage,germline clone,maternal effect,some die during embryonic stage,viable,sterile,recessive,mitotic cell cycle defective,female sterile,visible,body size defective,radiation sensitive,dominant,long lived,male sterile,partially lethal - majority die,partially,female fertile,male fertile,fertile,poor" "intersegmental nerve branch ISNb of A1-7,pole cell,embryo,germline clone,maternal effect,cycle 14 embryo,embryonic/first instar larval cuticle,oocyte,nurse cell,ectopic,microtubule organizing center & oocyte,oocyte & centrosome,microtubule & oocyte,anterior crossvein,posterior crossvein,segmental nerve branch SNa of A1-7,eye,eye photoreceptor cell,ommatidium" DRSC16370 I -0.565376865 -1.796429721 -0.961766681 -0.134939549 -1.052256199 0.327555361 FBgn0023167 SmD3 Small ribonucleoprotein particle protein SmD3 http://flybase.org/reports/FBgn0023167 - protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000596745 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:11160 "muscle organ development ; GO:0007517 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype neuron differentiation ; GO:0030182 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000596745 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype spliceosomal snRNP assembly ; GO:0000387 | inferred from biological aspect of ancestor with PANTHER:PTN000596745 lymph gland development ; GO:0048542 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004137" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U4 snRNP ; GO:0005687 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 pole plasm ; GO:0045495 | inferred from direct assay spliceosomal tri-snRNP complex ; GO:0097526 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 prespliceosome ; GO:0071010 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 pICln-Sm protein complex ; GO:0034715 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 small nuclear ribonucleoprotein complex ; GO:0030532 | traceable author statement SMN-Sm protein complex ; GO:0034719 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 nucleus ; GO:0005634 | inferred from direct assay U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 precatalytic spliceosome ; GO:0071011 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 commitment complex ; GO:0000243 | inferred from biological aspect of ancestor with PANTHER:PTN000596880 "SmD3, CG8427, Sm D3, guf, snRNP Sm D3, guf2, l(2)90/37, l(2)154/1, l(2)131/7, SYM10, smD3, dD3, smd3" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR034099:Small nuclear ribonucleoprotein Sm D3, IPR027141:Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3" CG8427 11-Aug-17 DroID_v2017_08 "Drer\snrpd3, Drer\snrpd3l" Scer\SMD3 Cele\snr-1 Xtro\snrpd3 Mmus\Snrpd3 Hsap\SNRPD3 embryonic stage "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal,lethal - all die before end of pupal stage,some die during pupal stage,viable" "ventral nerve cord,chordotonal organ,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic/larval somatic muscle,embryonic visceral muscle,embryonic/larval lymph gland,imaginal disc,embryonic/larval optic lobe,wing disc,haltere disc,ventral thoracic disc,embryonic/larval brain,embryonic/larval salivary gland,pole cell,maternal effect" DRSC07553 I -0.661107439 2.147955676 -0.659861544 -0.346204654 -1.293801523 -0.394581391 FBgn0029756 CG3309 - http://flybase.org/reports/FBgn0029756 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000342429 positive regulation of GTPase activity ; GO:0043547 | inferred from biological aspect of ancestor with PANTHER:PTN000342429 recycling endosome ; GO:0055037 | inferred from biological aspect of ancestor with PANTHER:PTN000342429 "BEST:LD39762, CG3309" "IPR024224:DENND6, IPR018307:AVL9/DENND6 domain" CG3309 11-Aug-17 DroID_v2017_08 "Drer\dennd6aa, Drer\dzip1l, Drer\dennd6b" - Cele\F53H1.3 "Xtro\dennd6b, Xtro\dennd6a" "Mmus\Dennd6b, Mmus\Dennd6a" "Hsap\DENND6B, Hsap\DENND6A" viable FBgn0065228 l(2)SH2193 lethal (2) SH2193 http://flybase.org/reports/FBgn0065228 gene - - - "l(2)SH2193, l(2)SH2 2193" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039431 plum plum http://flybase.org/reports/FBgn0039431 protein_coding_gene - negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype dendrite ; GO:0030425 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "CT20213, CG6490, plum, Plum" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG6490 11-Aug-17 DroID_v2017_08 "Drer\boc, Drer\cdon" - Cele\C34F6.10 "Xtro\cdon, Xtro\boc" "Mmus\Cdon, Mmus\Boc, Mmus\Neo1" "Hsap\BOC, Hsap\CDON" "neuroanatomy defective,somatic clone,viable,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "gamma Kenyon cell,somatic clone,embryonic/larval neuromuscular junction,transverse nerve,embryonic/larval neuromuscular junction | larval stage" FBgn0000996 dup double parked http://flybase.org/reports/FBgn0000996 "FBgn0004160, FBgn0022220, FBgn0034016, FBgn0063791" protein_coding_gene - glial cell growth ; GO:0042065 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype DNA replication ; GO:0006260 | traceable author statement antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype DNA replication checkpoint ; GO:0000076 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay replication fork ; GO:0005657 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CDT1, Cdt1, Dup, DUP/CDT1, CDT1/DUP, fs(2)PA77, DUP, cdt1/dup, CG8171, l(2)k03308, l(2)51Ec, 19k, fs(2)ltoPA77, fs(2)51Fa, anon-WO0257455.31, dup, cdt1" "IPR014939:CDT1 Geminin-binding domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR032054:DNA replication factor Cdt1, C-terminal" CG8171 11-Aug-17 DroID_v2017_08 Drer\cdt1 - Cele\cdt-1 Xtro\cdt1 Mmus\Cdt1 Hsap\CDT1 "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,cytokinesis defective,increased cell death,female sterile,maternal effect,neuroanatomy defective,increased cell size,endomitotic cell cycle defective,decreased cell size" "imaginal disc,mitotic cell cycle,S phase | embryonic cycle 16,cycle 16 embryo,mitosis & nuclear chromosome,mitotic metaphase,S phase,metaphase plate,kinetochore | maternal effect,follicle cell,eye disc,embryonic/larval brain | third instar larval stage,embryonic/larval glial cell | third instar larval stage,subperineurial glial cell,embryonic/larval neuroblast,ectopic | third instar larval stage" DRSC07088 IEK -1.833129236 -3.906995979 -4.172235799 -6.712987859 5.494449105 10.08728796 FBgn0003967 vam vacuolar medulla http://flybase.org/reports/FBgn0003967 - gene - - - "Vam, vam" - - 11-Aug-17 DroID_v2017_08 - - - - - - "neurophysiology defective,neuroanatomy defective,optomotor response defective" "medulla,lamina,lobula,brain,lamina monopolar neuron L1,lamina monopolar neuron L2" FBgn0086222 sheepish sheepish http://flybase.org/reports/FBgn0086222 gene - - - sheepish - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,recessive" FBgn0010808 Chchd3 Coiled-coil-helix-coiled-coil-helix domain containing 3 http://flybase.org/reports/FBgn0010808 "FBgn0015363, FBgn0027990" protein_coding_gene - mitochondrial fusion ; GO:0008053 | inferred from mutant phenotype cristae formation ; GO:0042407 | inferred from mutant phenotype mitochondrial inner membrane ; GO:0005743 | inferred from direct assay "pMY8, l(3)96601, anon-l, l(3)3670, l(3)S127408, x94917, 1274/08, 0966/01, 0812/02, 0353/13, 0205/14, CG1715, Chchd3, l(3)03670, ChChd3" IPR012471:Protein of unknown function DUF1690 CG1715 11-Aug-17 DroID_v2017_08 "Drer\chchd3a, Drer\chchd3b, Drer\chchd6a, Drer\chchd6b" Scer\COX23 Cele\chch-3 "Xtro\chchd3, Xtro\chchd6" "Mmus\Chchd3, Mmus\Chchd6" "Hsap\CHCHD3, Hsap\CHCHD6" adult stage "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,viable" DRSC16981 E -0.569093387 -0.243250154 -0.33140152 -2.435481629 0.079139689 0.462181033 FBgn0024194 rasp rasp http://flybase.org/reports/FBgn0024194 "FBgn0002450, FBgn0004562, FBgn0005227, FBgn0035406, FBgn0044333" protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from mutant phenotype transferase activity, transferring acyl groups ; GO:0016746 | non-traceable author statement palmitoyltransferase activity ; GO:0016409 | inferred from mutant phenotype" N-terminal peptidyl-L-cysteine N-palmitoylation ; GO:0018009 | inferred from mutant phenotype protein palmitoylation ; GO:0018345 | inferred from direct assay N-terminal peptidyl-L-cysteine N-palmitoylation ; GO:0018009 | inferred from direct assay smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | non-traceable author statement "ski, Rasp, sit, l(3)63Bg, CG11495, cmn, ski/sit, sig/ski, rsp, l(3)SG3, l(3)m47, l(3)M47, 7F21, rasp, cnm, RASP" "IPR004299:Membrane bound O-acyl transferase, MBOAT" CG11495 11-Aug-17 DroID_v2017_08 "Drer\hhatlb, Drer\hhat, Drer\hhatla" "Scer\GUP1, Scer\GUP2" "Cele\hhat-1, Cele\hhat-2" "Xtro\hhat, Xtro\hhatl" "Mmus\Hhat, Mmus\Hhatl" "Hsap\HHATL, Hsap\HHAT" "lethal,visible,recessive,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,segment polarity phenotype,wild-type,maternal effect,germline clone,lethal - all die before end of larval stage,some die during larval stage,viable" "dorsal appendage,germline clone,maternal effect,eye,somatic clone,wing,embryo,embryonic/first instar larval cuticle,wing disc,wing vein L2,wing vein L3,wing vein L4,wing vein L5,eye disc,photoreceptor cell,cell non-autonomous,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,eye-antennal disc,ventral thoracic disc,imaginal disc,wing vein" FBgn0011761 dhd deadhead http://flybase.org/reports/FBgn0011761 - protein_coding_gene "protein disulfide oxidoreductase activity ; GO:0015035 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence or structural similarity with SGD:S000004033 disulfide oxidoreductase activity ; GO:0015036 | inferred from direct assay thioredoxin-disulfide reductase activity ; GO:0004791 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ; GO:0016671 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 protein-disulfide reductase activity ; GO:0047134 | inferred from biological aspect of ancestor with PANTHER:PTN000047179" glycerol ether metabolic process ; GO:0006662 | inferred from electronic annotation with InterPro:IPR005746 cell redox homeostasis ; GO:0045454 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype head development ; GO:0060322 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000047179 nucleus ; GO:0005634 | inferred from direct assay "DmTrx-1, Trx-1, CG4193, dhd, Dmdhd, Dmeldhd, Dhd, 4193, DHD" "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site, IPR005746:Thioredoxin" CG4193 11-Aug-17 DroID_v2017_08 "Drer\txn, Drer\ahnak, Drer\zgc:56493, Drer\txn2" "Scer\TRX3, Scer\TRX2, Scer\TRX1" "Cele\trx-4, Cele\trx-2, Cele\Y55F3AR.2, Cele\trx-1, Cele\W01B11.6" "Xtro\LOC100170420, Xtro\ahnak, Xtro\txn, Xtro\txn2, Xtro\prx" "Mmus\Txn2, Mmus\Txndc2, Mmus\Ahnak2, Mmus\Ahnak, Mmus\Txndc8, Mmus\Txn1" "Hsap\AHNAK, Hsap\TXN, Hsap\TXNDC8, Hsap\TXNDC2, Hsap\TXN2, Hsap\AHNAK2" " adult stage && oogenesis stage | stage >=S9 , embryonic stage | early , adult stage | male , adult stage | female " " nurse cell

,

ubiquitous " "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,female sterile,wild-type,lethal,viable,visible" "embryo,maternal effect,embryonic head,blastoderm embryo,gastrula embryo,pronucleus | maternal effect,polar body nucleus,lateral process,cephalopharyngeal skeleton,chaeta,supernumerary" FBgn0013720 pck pickel http://flybase.org/reports/FBgn0013720 "FBgn0001369, FBgn0025384, FBgn0027323, FBgn0027333" protein_coding_gene - "open tracheal system development ; GO:0007424 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004031 integral component of membrane ; GO:0016021 | inferred from sequence model septate junction ; GO:0005918 | inferred from sequence or structural similarity with sinu septate junction ; GO:0005918 | inferred from direct assay "Pck, mega, Mega, CG14779, l(1)G0044, EG:80H7.2, pck, PCK" IPR004031:PMP-22/EMP/MP20/Claudin superfamily CG14779 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "transverse connective primordium,dorsal trunk primordium,pleated septate junction & tracheal system,embryonic/larval dorsal trunk,embryonic/larval trachea,embryonic/larval tracheal system,trachea,embryonic dorsal trunk & cell,embryonic/larval transverse connective,cuticle,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt" FBgn0014269 prod proliferation disrupter http://flybase.org/reports/FBgn0014269 FBgn0034409 protein_coding_gene - mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype lymph gland development ; GO:0048542 | inferred from mutant phenotype regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype "chromocenter ; GO:0010369 | NOT inferred from direct assay pericentric heterochromatin ; GO:0005721 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay nuclear euchromatin ; GO:0005719 | inferred from direct assay" "Prod, CG18608, PROD, l(2)88/10, l(2)k08810, prod" IPR028002:Myb/SANT-like DNA-binding domain CG18608 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage -- adult stage " adult stage , larval stage , embryonic stage "

ubiquitous "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,hyperplasia,viable,fertile,wild-type,partially,semi-sterile,visible,locomotor rhythm defective" "imaginal disc,embryonic/larval lymph gland,embryonic/larval brain,leg & adult cuticle | somatic clone,adult cuticle,somatic clone,leg & macrochaeta | somatic clone,macrochaeta,mitosis & nuclear chromosome,eye-antennal disc,eye" FBgn0082304 Rfx2 Rfx2 http://flybase.org/reports/FBgn0082304 gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003150 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003150" - "Rfx2, drfx2, dRFX2" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR003150:DNA-binding RFX-type winged-helix domain" - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,visible,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage" "melanotic mass,chaeta,eye,ommatidium,eye disc" FBgn0039111 PTPMT1 "Protein tyrosine phosphatase, mitochondrial 1" http://flybase.org/reports/FBgn0039111 protein_coding_gene "protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR020422 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ; GO:0004439 | inferred from biological aspect of ancestor with PANTHER:PTN000016644 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ; GO:0004439 | inferred from sequence or structural similarity with MGI:MGI:1913711" "protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR020422 protein dephosphorylation ; GO:0006470 | non-traceable author statement dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with MGI:MGI:1913711 neurogenesis ; GO:0022008 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:1913711 "150466_at, PLIP, CG10371, dPTEN, plip, PTPMT1, Plip" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like, IPR020422:Dual specificity protein phosphatase domain" CG10371 11-Aug-17 DroID_v2017_08 Drer\ptpmt1 - "Cele\lip-1, Cele\F28C6.8" - Mmus\Ptpmt1 Hsap\PTPMT1 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0010356 Taf5 TBP-associated factor 5 http://flybase.org/reports/FBgn0010356 FBgn0033563 protein_coding_gene "transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay" neurogenesis ; GO:0022008 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11539 inferred from sequence or structural similarity with HGNC:17304 inferred from sequence or structural similarity with SGD:S000000402 positive regulation of transcription of Notch receptor target ; GO:0007221 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11539 inferred from sequence or structural similarity with HGNC:17304 inferred from sequence or structural similarity with SGD:S000000402 transcription factor TFIID complex ; GO:0005669 | inferred from physical interaction with Taf4 inferred from physical interaction with Taf6 transcription factor TFIID complex ; GO:0005669 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "TAF[II]80, dmTAF5, dmTaf5, dTAF[[II]]80, TAF80/85, TAF, TFIID, TAF[[II]]80, TAF[[II]], Taf80, TAF5, dTAFII85, CG7704, d80, TFIID 85, TAF[[II]]80/85, TAF80, TAFII80, Taf[[II]]80, dTAFii80, p85, Taf85, Taf5, TAFII85, TAF[[II]]85, dTAF5" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR007582:TFIID subunit TAF5, NTD2 domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG7704 11-Aug-17 DroID_v2017_08 "Drer\taf5l, Drer\egln2, Drer\egln1a, Drer\taf5, Drer\egln3, Drer\egln1b" Scer\TAF5 Cele\taf-5 "Xtro\taf5l, Xtro\egln3, Xtro\egln1, Xtro\taf5, Xtro\egln2" "Mmus\Egln3, Mmus\Taf5, Mmus\Egln2, Mmus\Taf5l, Mmus\Wdr38, Mmus\Egln1" "Hsap\TAF5, Hsap\EGLN3, Hsap\TAF5L, Hsap\EGLN1, Hsap\EGLN2" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC07562 IK -2.007286284 0.831044293 -0.471737886 0.070591137 2.680770546 2.044664495 FBgn0047338 CG32148 - http://flybase.org/reports/FBgn0047338 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "NEST:bs21b09, BcDNA:AT21341, CG32148" - CG32148 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC28787 K -0.64396536 0.655734334 -0.183471322 0.996074183 -0.613123327 2.195369706 FBgn0004400 rhi rhino http://flybase.org/reports/FBgn0004400 FBgn0034254 protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 chromatin binding ; GO:0003682 | inferred from direct assay piRNA metabolic process ; GO:0034587 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay chromatin ; GO:0000785 | inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 inferred from sequence or structural similarity with Su(var)205 heterochromatin ; GO:0000792 | inferred from direct assay "rno, CG10683, rhi, HP1D, Rhi, RHI, rhino, HP1d, HP1, Rhino" "IPR000953:Chromo/chromo shadow domain, IPR016197:Chromo domain-like, IPR023780:Chromo domain" CG10683 11-Aug-17 DroID_v2017_08 "Drer\cbx3b, Drer\cbx3a" "Scer\YPR158W-A, Scer\YHL009W-B, Scer\YJR026W, Scer\YGR038C-A, Scer\YOR343W-A, Scer\YML045W, Scer\YFL002W-B, Scer\YNL284C-B, Scer\YHR214C-C, Scer\YOR142W-A, Scer\YNL284C-A, Scer\YBL100W-A, Scer\YMR046C, Scer\YDR098C-B, Scer\YPL257W-A, Scer\YDR210W-A, Scer\YJR028W, Scer\YGR109W-B, Scer\YHR214C-B, Scer\YBL005W-A, Scer\YBL005W-B, Scer\YDR210C-D, Scer\YFL002W-A, Scer\YMR050C, Scer\YOL103W-A, Scer\YDR210C-C, Scer\YDR034C-D, Scer\YPR158C-D, Scer\YLR227W-A, Scer\YDR261W-B, Scer\YDR261W-A, Scer\YGR109W-A, Scer\YJL114W, Scer\YDR170W-A, Scer\YIL082W-A, Scer\YNL054W-A, Scer\YOR192C-B, Scer\YGR038C-B, Scer\YLR410W-A, Scer\YPR158W-B, Scer\YBL100W-B, Scer\YGR161W-A, Scer\YAR009C, Scer\YDR261C-C, Scer\YLR256W-A, Scer\YOL103W-B, Scer\YPR137C-A, Scer\YGR161C-C, Scer\YPL257W-B, Scer\YDR365W-A, Scer\YER138C, Scer\YJR027W, Scer\YLR410W-B, Scer\YHL009W-A, Scer\YER137C-A, Scer\YDR316W-A, Scer\YMR051C, Scer\YPR137C-B, Scer\YMR045C, Scer\YML039W, Scer\YBR012W-B, Scer\YDR365W-B, Scer\YLR227W-B, Scer\YGR027W-B, Scer\YJL113W, Scer\YGR027W-A, Scer\YJR029W, Scer\YDR261C-D, Scer\YER159C-A, Scer\YCL020W, Scer\YGR161W-B, Scer\YDR034C-C, Scer\YOR343W-B, Scer\YLR157C-A, Scer\YOR142W-B, Scer\YML040W, Scer\YPR158C-C, Scer\YGR161C-D, Scer\YOR192C-A, Scer\YDR098C-A, Scer\YDR210W-B, Scer\YLR157C-B, Scer\YBR012W-A, Scer\YAR010C, Scer\YML045W-A, Scer\YER160C, Scer\YLR035C-A, Scer\YCL019W, Scer\YDR316W-B" "Cele\set-31, Cele\hpl-1, Cele\cec-9, Cele\cec-3" - "Mmus\Gin1, Mmus\Cbx3, Mmus\Rtl1" "Hsap\RTL1, Hsap\ZBED9, Hsap\NYNRIN, Hsap\CBX3, Hsap\KRBA2, Hsap\GIN1" "female sterile,recessive,viable,fertile,female fertile" "nurse cell & chromatin,egg chamber,nurse cell,dorsal appendage,egg,maternal effect" FBgn0035153 ebd1 earthbound 1 http://flybase.org/reports/FBgn0035153 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with Apc inferred from genetic interaction with lgs adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - "earthbound 1, CG3371, EP3592, ebd1, Ebd1" "IPR007889:DNA binding HTH domain, Psq-type, IPR006600:HTH CenpB-type DNA-binding domain, IPR009057:Homeobox domain-like, IPR029058:Alpha/Beta hydrolase fold" CG3371 11-Aug-17 DroID_v2017_08 Drer\zbtb12.2 - - - Mmus\Zbtb12 Hsap\ZBTB12 "viable,neuroanatomy defective" "dorsal medial muscle,indirect flight muscle,anterior fascicle & synapse,intersegmental nerve" DRSC08565 E -0.507399311 0.482778218 0.480277595 -1.897574842 0.179935432 -0.65174558 FBgn0024192 sag semang http://flybase.org/reports/FBgn0024192 - gene - embryonic digestive tract morphogenesis ; GO:0048557 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype R1/R6 cell fate commitment ; GO:0007462 | inferred from mutant phenotype R7 cell fate commitment ; GO:0007465 | inferred from mutant phenotype compound eye cone cell fate commitment ; GO:0042676 | inferred from mutant phenotype - sag - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,rescuable maternal effect,germline clone" "eye photoreceptor cell,eye,ommatidium,eye disc,photoreceptor cell R7,somatic clone,pigment granule | somatic clone,rhabdomere,mitotic cell cycle & eye disc,anal pad,germline clone,embryonic abdominal segment 8,cephalopharyngeal skeleton,midgut constriction,presumptive embryonic/larval peripheral nervous system,embryonic/larval trachea,chordotonal organ,external sensory organ,wing vein L4,cone cell,pigment cell,photoreceptor cell R1,photoreceptor cell R6" FBgn0011726 tsr twinstar http://flybase.org/reports/FBgn0011726 "FBgn0011567, FBgn0020533, FBgn0020539, FBgn0022163, FBgn0024209" protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from sequence or structural similarity with HGNC:1874 inferred from sequence or structural similarity with SGD:S000003973 inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype actin filament polymerization ; GO:0030041 | inferred from mutant phenotype regulation of lamellipodium assembly ; GO:0010591 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype actin filament depolymerization ; GO:0030042 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype centrosome separation ; GO:0051299 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | traceable author statement cell morphogenesis ; GO:0000902 | inferred from mutant phenotype meiotic cytokinesis ; GO:0033206 | inferred from mutant phenotype lamellipodium assembly ; GO:0030032 | inferred from mutant phenotype imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from genetic interaction with mbt epithelial structure maintenance ; GO:0010669 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype female gonad development ; GO:0008585 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype positive regulation of protein secretion ; GO:0050714 | inferred from mutant phenotype actin cytoskeleton ; GO:0015629 | inferred from electronic annotation with InterPro:IPR017904 microtubule associated complex ; GO:0005875 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "cofilin, Adf, cofilin/ADF, ADF/cofilin, CG4254, T8, D-cof, cofilin/actin depolymerizing factor homolog, ntf, 12/8, l(2)k05633, l(2)03101, D61, l(2)k13409, l(2)k03101, Cadf, tsr, Tsr, ADF" "IPR002108:Actin-depolymerising factor homology domain, IPR029006:ADF-H/Gelsolin-like domain, IPR017904:ADF/Cofilin" CG4254 11-Aug-17 DroID_v2017_08 "Drer\cfl1l, Drer\cfl1, Drer\cfl2" Scer\COF1 Cele\unc-60 "Xtro\cfl1, Xtro\dstn, Xtro\cfl2" "Mmus\Cfl1, Mmus\Cfl2, Mmus\Dstn" "Hsap\CFL1, Hsap\CFL2, Hsap\DSTN" embryonic stage -- adult stage "neuroanatomy defective,somatic clone,lethal,sterile,partially lethal - majority die,some die during pupal stage,partially lethal - majority live,male sterile,heat sensitive,female sterile,viable,male fertile,partially,lethal - all die before end of pupal stage,recessive,wild-type,visible,cytokinesis defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,cold sensitive,cell polarity defective" "adult mushroom body,somatic clone,terminal filament,heat sensitive,chaeta,ovary,actin filament | heat sensitive,border follicle cell,nurse cell & nucleus,eye,retina,optic lobe,lamina,rhabdomereGMR.Pc, tsr‘î96,rhabdomere membraneGMR.Pc, tsr‘î96,ommatidium,rhabdomereGMR.Pc,rhabdomere membraneGMR.Pc,rhabdomere,actin cytoskeleton & eye disc | somatic clone,imaginal disc,Nebenkern,spermatid,aster & primary spermatocyte cyst,meiotic prophase I,aster & secondary spermatocyte,meiotic prophase II,spermatocyte ring canal,spermatocyte fusome,oocyte & actin filament | ectopic | germ-line clone,follicle cell & actin filament | ectopic | somatic clone,follicle cell,adult mushroom body & axon | somatic clone,wing hair,filamentous actin | somatic clone,actomyosin contractile ring,microchaeta,wing & filamentous actin, with tsr139.cBa, tsrV27Q.cBa,adult abdominal sensillum,leg sensillum,bract,wing & filamentous actin,rhabdomereGMR.Pc, tsrUAS.cPa,rhabdomere membraneGMR.Pc, tsrUAS.cPa,wing & filamentous actin, with tsr‘î96, tsrV27Q.cBa,wing & filamentous actin, with tsr‘î96, tsr139.cBa,adult olfactory receptor neuron Or59c,dendrite109(2)80" DRSC04718 K -0.234560469 1.041267168 1.048872533 -0.339004784 2.595206503 2.403453655 FBgn0004242 Syt1 Synaptotagmin 1 http://flybase.org/reports/FBgn0004242 "FBgn0005767, FBgn0022151" protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with stnB inferred from physical interaction with stnA SNARE binding ; GO:0000149 | inferred from physical interaction with Snap25, Syx1A calcium-dependent phospholipid binding ; GO:0005544 | traceable author statement clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 protein homodimerization activity ; GO:0042803 | inferred from direct assay calcium-dependent phospholipid binding ; GO:0005544 | inferred from direct assay calcium ion binding ; GO:0005509 | inferred from direct assay phosphatidylserine binding ; GO:0001786 | inferred from direct assay calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285" neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype rhythmic synaptic transmission ; GO:0060024 | inferred from direct assay chemical synaptic transmission ; GO:0007268 | inferred from direct assay regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from mutant phenotype regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | traceable author statement synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity regulation of calcium ion-dependent exocytosis ; GO:0017158 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 positive regulation of vesicle fusion ; GO:0031340 | inferred from direct assay synaptic vesicle endocytosis ; GO:0048488 | inferred from direct assay larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement regulation of synapse structure or activity ; GO:0050803 | inferred from mutant phenotype neuromuscular junction ; GO:0031594 | inferred from direct assay integral component of synaptic vesicle membrane ; GO:0030285 | non-traceable author statement synaptic vesicle ; GO:0008021 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity terminal bouton ; GO:0043195 | inferred from direct assay synaptic vesicle membrane ; GO:0030672 | inferred from biological aspect of ancestor with PANTHER:PTN000740739 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 neuromuscular junction ; GO:0031594 | "syt, dsyt1, dsytI, SYT, Syt, DSYT2, SytI, syt-1, sytI, Dsyt2, Syt1, CG3139, SYT1, l(2)k05909, SYT I, D. Syt I, l(2)23Ba, DSYT, l(2)23AB1, Syt I, syt1, DSyt1, syt I, DSyt, dSYT, Syt-1, syt 1, Droso1, Syt 1, DSypt, STY1, dSyt1, syn" "IPR000008:C2 domain, IPR001565:Synaptotagmin, IPR015428:Synaptotagmin 1/2" CG3139 11-Aug-17 DroID_v2017_08 "Drer\syt2a, Drer\syt1b, Drer\syt8, Drer\syt3, Drer\syt10, Drer\syt5a, Drer\LOC559637, Drer\syt19, Drer\syt1a, Drer\syt9b, Drer\syt6b, Drer\syt6a, Drer\syt9a, Drer\syt5b" - "Cele\snt-2, Cele\snt-1, Cele\snt-3, Cele\snt-5, Cele\snt-6" "Xtro\syt6, Xtro\syt1, Xtro\syt8, Xtro\syt5, Xtro\syt3" "Mmus\Syt2, Mmus\Syt5, Mmus\Syt9, Mmus\Syt8, Mmus\Syt3, Mmus\Syt6, Mmus\Syt10, Mmus\Syt1" "Hsap\SYT9, Hsap\SYT5, Hsap\SYT3, Hsap\SYT1, Hsap\SYT2, Hsap\SYT8, Hsap\SYT10" " embryonic stage |>8-12 hr , embryonic stage | stage >=13 , adult stage , embryonic stage | stage 17 , embryonic stage -- adult stage , embryonic stage | stage 15-17 , larval stage--pupal stage , embryonic stage | 12-20 hr , embryonic stage | stage >15 " " embryonic central nervous system

, adult head

, central nervous system

, thoracico-abdominal ganglion

, embryonic peripheral nervous system

, adult brain

, ventral nerve cord

" " larval stage , embryonic stage | stage 16 , embryonic stage | stage 14-17 , embryonic stage | stage 17 , larval stage | third instar , larval stage | first instar , embryonic stage , larval stage | second instar , adult stage , larval stage--adult stage " " neuromuscular junction

, motor neuron

, central nervous system | restricted

, neuropil

, optic neuropil

, synapse

,synapse

, embryonic peripheral nervous system | restricted

" "neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,behavior defective,lethal - all die before end of larval stage,some die during larval stage,uncoordinated,locomotor rhythm defective,some die during third instar larval stage,wild-type,conditional,flightless,neuroanatomy defective,viable,flight defective,locomotor behavior defective" "crystal cell,neuromuscular junction,synapse | larval stage,synaptic vesicle,synapseelav.PLu,egg,germline clone,synaptic vesicle | third instar larval stage,synaptic vesicleelav.PLu, Syt1KQ.UAS,synaptic vesicleelav.PLu, Syt1AD4, Syt1KQ.UAS,embryonic/larval neuromuscular junction,synapse | embryonic stage,eye,somatic clone,photoreceptor cell & synapse,bouton,supernumerary,synapse,neuron,synaptic vesicleelav.PLu, Syt1KQ.UAS, Syt1N13,wing,synaptic vesicleelav.PLu, Syt1AD4/Syt1N13,synaptic vesicleelav.PLu, Syt1AD4, Syt1N13" DRSC00156 I -2.270164249 0.827424096 0.194495777 -0.73538698 0.316217495 -0.383072571 FBgn0005346 Scarred Scarred http://flybase.org/reports/FBgn0005346 - gene - - - "Scar, Scarred" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,heat sensitive,lethal,recessive" "eye,heat sensitive,wing" FBgn0028040 l(3)S099312 lethal (3) S099312 http://flybase.org/reports/FBgn0028040 gene - - - l(3)S099312 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0035106 rno rhinoceros http://flybase.org/reports/FBgn0035106 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG7036, rno" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019542:Enhancer of polycomb-like, N-terminal, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR034732:Extended PHD (ePHD) domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7036 11-Aug-17 DroID_v2017_08 "Drer\mllt10, Drer\brpf3b, Drer\brd1a, Drer\brpf3a, Drer\jade1, Drer\jade2, Drer\jade3" Scer\NTO1 "Cele\zfp-1, Cele\lin-49, Cele\phf-15" "Xtro\brd1, Xtro\jade2, Xtro\brpf3, Xtro\jade1, Xtro\jade3" "Mmus\Jade2, Mmus\Brpf1, Mmus\Brpf3, Mmus\Jade3, Mmus\Mllt6, Mmus\Brd1, Mmus\Jade1, Mmus\Mllt10" "Hsap\JADE1, Hsap\JADE2, Hsap\MLLT6, Hsap\BRPF3, Hsap\BRPF1, Hsap\MLLT10, Hsap\BRD1, Hsap\JADE3" "lethal,recessive,increased cell number,somatic clone,decreased cell death,viable,visible" "photoreceptor cell R8,somatic clone,photoreceptor cell,cone cell,ommatidium,arista,leg,ectopic,ommatidium & photoreceptor | ectopic | somatic clone,ommatidium & photoreceptor | ectopic | somatic clone | cell non-autonomous,photoreceptor cell R3,photoreceptor cell R4,pigment cell,interommatidial bristle | P-stage,pigment cell | P-stage,eye,rhabdomereGMR.PF,mesothoracic tergum" DRSC08584 K -0.818149608 0.129538168 -0.946593527 0.979555488 0.359932768 1.873059763 FBgn0263598 Vha68-2 Vacuolar H[+] ATPase 68 kDa subunit 2 http://flybase.org/reports/FBgn0263598 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000389800" "ATP metabolic process ; GO:0046034 | inferred from electronic annotation with InterPro:IPR004100, InterPro:IPR022878 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000793, InterPro:IPR005725 lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype endosomal lumen acidification ; GO:0048388 | inferred from mutant phenotype imaginal disc growth ; GO:0007446 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 endosomal transport ; GO:0016197 | inferred from mutant phenotype" "plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD:S000002344 lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN001032512" "CG3762, vha68-2, l(2)s4214, l(2)01510, Vha68-2, MENE-R6, Vha68.2, ATP6V1A, Vha68, A subunit, vha67-2, RE30552p" "IPR024034:ATPase, F1/V1 complex, beta/alpha subunit, C-terminal, IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005725:ATPase, V1 complex, subunit A, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR022878:V-type ATP synthase catalytic alpha chain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031686:ATPsynthase alpha/beta subunit, N-terminal extension" CG3762 11-Aug-17 DroID_v2017_08 "Drer\atp6v1aa, Drer\atp6v1ab" Scer\VMA1 Cele\vha-13 Xtro\atp6v1a Mmus\Atp6v1a Hsap\ATP6V1A FBgn0053823 His2A:CG33823 His2A:CG33823 http://flybase.org/reports/FBgn0053823 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33823, His2A:CG33823" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33823 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-368j24.14, Drer\si:ch73-36p18.5, Drer\zgc:195633, Drer\LOC100332229, Drer\si:ch1073-159d7.10, Drer\si:dkey-261m9.11, Drer\zgc:173652, Drer\si:dkey-261m9.18, Drer\si:dkey-23a13.7, Drer\si:dkey-108k21.15, Drer\fbxl6, Drer\h2afy2, Drer\si:dkey-108k21.19, Drer\si:ch211-113a14.19, Drer\LOC100334934, Drer\LOC570115, Drer\si:dkey-261m9.7, Drer\si:ch73-368j24.13, Drer\zgc:110434, Drer\si:dkey-108k21.26, Drer\zgc:101846, Drer\si:ch211-113a14.7, Drer\h2afx, Drer\si:ch1073-159d7.11, Drer\LOC100148591, Drer\si:ch211-113a14.26, Drer\si:dkey-261m9.15, Drer\si:dkey-23a13.20, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.14, Drer\si:ch211-113a14.16, Drer\zgc:154164, Drer\zgc:114037" "Scer\HTA1, Scer\HTA2" "Cele\his-61, Cele\his-12, Cele\his-47, Cele\his-16, Cele\his-43, Cele\his-35, Cele\his-57, Cele\his-53, Cele\his-3, Cele\his-65, Cele\his-51, Cele\his-30, Cele\his-68, Cele\his-21, Cele\his-19, Cele\his-33, Cele\htas-1, Cele\his-7" "Xtro\hist1h2ah, Xtro\hist1h2am, Xtro\hist1h2aa, Xtro\h2afy2, Xtro\h2afx, Xtro\hist1h2aj, Xtro\hist1h2ad, Xtro\h2afy, Xtro\h2afj" "Mmus\H2afy, Mmus\Hist3h2a, Mmus\H2afb2, Mmus\Hist2h2aa2, Mmus\Hist1h2ao, Mmus\H2afy2, Mmus\Hist2h3c1, Mmus\H2afb1, Mmus\Hist1h2an, Mmus\Hist2h2aa1, Mmus\Hist1h2ag, Mmus\Hist1h2af, Mmus\H2afj, Mmus\Gm14920, Mmus\H2al1n, Mmus\H2afb3, Mmus\Hist1h2ap, Mmus\Hist1h2ad, Mmus\Hist1h2ae, Mmus\Hist1h2ah, Mmus\Hist1h2ab, Mmus\H2al2c, Mmus\H2al2b, Mmus\Hist1h2ac, Mmus\H2afx, Mmus\Hist1h2aa, Mmus\Hist1h2ai, Mmus\Hist1h2ak, Mmus\H2al1j, Mmus\Hist2h2ab, Mmus\Hist2h2ac" "Hsap\HIST1H2AB, Hsap\H2AFJ, Hsap\HIST1H2AG, Hsap\HIST1H2AD, Hsap\HIST3H2A, Hsap\HIST1H2AE, Hsap\H2AFB3, Hsap\HIST1H2AC, Hsap\H2AFX, Hsap\HIST2H2AA4, Hsap\H2AFY, Hsap\HIST1H2AH, Hsap\HIST1H2AK, Hsap\HIST1H2AA, Hsap\H2AFB2, Hsap\HIST1H2AM, Hsap\HIST1H2AJ, Hsap\HIST2H2AC, Hsap\HIST2H2AB, Hsap\HIST1H2AI, Hsap\HIST1H2AL, Hsap\H2AFB1, Hsap\H2AFY2, Hsap\HIST2H2AA3" FBgn0053890 His2B:CG33890 His2B:CG33890 http://flybase.org/reports/FBgn0053890 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33890, His2B:CG33890" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33890 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-36p18.3, Drer\ano9a, Drer\si:ch73-368j24.8, Drer\LOC100329560, Drer\si:dkey-261m9.6, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.1, Drer\si:ch1073-153i20.3, Drer\si:ch1073-159d7.13, Drer\si:dkey-261m9.19, Drer\hist1h2ba, Drer\hist2h2l, Drer\si:ch211-113a14.28, Drer\zgc:114046, Drer\si:dkey-23a13.5, Drer\LOC100329290, Drer\si:ch1073-159d7.5, Drer\zgc:173587, Drer\zgc:173585, Drer\zgc:92591, Drer\LOC100334559, Drer\zgc:194989, Drer\si:dkey-108k21.11, Drer\LOC100334869, Drer\si:dkey-23a13.16, Drer\si:ch211-113a14.29, Drer\si:dkey-108k21.27" "Scer\HTB2, Scer\HTB1" "Cele\his-54, Cele\his-41, Cele\his-39, Cele\his-20, Cele\his-22, Cele\his-29, Cele\his-66, Cele\his-62, Cele\his-52, Cele\his-48, Cele\his-4, Cele\his-58, Cele\his-11, Cele\his-44, Cele\his-8, Cele\his-34, Cele\his-15" "Xtro\LOC100497082, Xtro\hist1h2bk, Xtro\LOC101734862, Xtro\LOC100495041, Xtro\LOC100492632, Xtro\LOC100496181, Xtro\hist1h2bm, Xtro\LOC100498329, Xtro\LOC101731852, Xtro\LOC100497915, Xtro\LOC101734494, Xtro\LOC101733171, Xtro\LOC100487485, Xtro\LOC100496445, Xtro\LOC101733489, Xtro\LOC100486150, Xtro\hist1h2bj, Xtro\LOC101735218, Xtro\LOC101730940, Xtro\hist2h2be, Xtro\LOC101731959, Xtro\LOC100485134, Xtro\LOC100486870, Xtro\LOC100498647, Xtro\LOC100496436, Xtro\LOC100498072, Xtro\LOC101733828, Xtro\LOC100495396, Xtro\LOC100485294, Xtro\LOC101731067, Xtro\LOC100495578, Xtro\LOC100498553, Xtro\LOC100495415, Xtro\LOC101735164" "Mmus\Hist1h2bj, Mmus\Hist3h2ba, Mmus\Hist2h2bb, Mmus\H2bfm, Mmus\Hist1h2bq, Mmus\Hist1h2bc, Mmus\Hist1h2bl, Mmus\Hist1h2be, Mmus\Hist1h2bp, Mmus\1700024P04Rik, Mmus\Hist1h2bb, Mmus\Hist1h2br, Mmus\Hist1h2bk, Mmus\Hist1h2bg, Mmus\Hist1h2bn, Mmus\Hist1h2ba, Mmus\Hist1h2bh, Mmus\Hist1h2bf, Mmus\Hist2h2be, Mmus\Hist1h2bm" "Hsap\HIST1H2BL, Hsap\HIST2H2BE, Hsap\HIST1H2BD, Hsap\HIST1H2BF, Hsap\HIST2H2BF, Hsap\HIST1H2BC, Hsap\HIST1H2BK, Hsap\H2BFM, Hsap\HIST1H2BE, Hsap\H2BFWT, Hsap\HIST1H2BJ, Hsap\HIST1H2BH, Hsap\HIST1H2BI, Hsap\HIST1H2BA, Hsap\HIST1H2BG, Hsap\HIST3H2BB, Hsap\HIST1H2BB, Hsap\HIST1H2BM, Hsap\HIST1H2BN, Hsap\HIST1H2BO" FBgn0037884 Arfip Arfaptin http://flybase.org/reports/FBgn0037884 protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from electronic annotation with InterPro:IPR010504 phospholipid binding ; GO:0005543 | inferred from direct assay dynactin binding ; GO:0034452 | inferred from physical interaction with DCTN1-p150 phosphatidylinositol-4-phosphate binding ; GO:0070273 | inferred from sequence or structural similarity with HGNC:21496 regulation of Arp2/3 complex-mediated actin nucleation ; GO:0034315 | inferred from biological aspect of ancestor with PANTHER:PTN000254123 positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype trans-Golgi network ; GO:0005802 | inferred from direct assay trans-Golgi network membrane ; GO:0032588 | inferred from sequence or structural similarity with HGNC:21496 "Arfip, CG17184, dCG17184-PA, arfip" "IPR010504:Arfaptin homology (AH) domain, IPR030798:Arfaptin family, IPR027267:Arfaptin homology (AH) domain/BAR domain" CG17184 11-Aug-17 DroID_v2017_08 "Drer\arfip1, Drer\arfip2b, Drer\arfip2a" - Cele\F54C8.7 "Xtro\arfip2, Xtro\arfip1" "Mmus\Arfip1, Mmus\Arfip2" "Hsap\ARFIP2, Hsap\ARFIP1" "viable,fertile,neuroanatomy defective,partially lethal,some die during pupal stage,chemical sensitive,recessive" "neurite | pharate adult stage,NMJ bouton,Golgi apparatus,supernumerary | third instar larval stage" FBgn0031491 alpha4GT1 alpha4GT1 http://flybase.org/reports/FBgn0031491 protein_coding_gene "alpha-1,4-N-acetylgalactosaminyltransferase activity ; GO:0035248 | inferred from direct assay acetylgalactosaminyltransferase activity ; GO:0008376 | inferred from mutant phenotype" glycosphingolipid biosynthetic process ; GO:0006688 | inferred from direct assay glycolipid biosynthetic process ; GO:0009247 | inferred from direct assay negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with rpr glycosphingolipid biosynthetic process ; GO:0006688 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with N - "CG17223, alpha4GT1, alpha-4GT1" "IPR007577:Glycosyltransferase, DXD sugar-binding motif, IPR007652:Alpha 1,4-glycosyltransferase domain, IPR029044:Nucleotide-diphospho-sugar transferases" CG17223 11-Aug-17 DroID_v2017_08 - - "Cele\Y20C6A.4, Cele\fbxb-7" "Xtro\LOC100493399, Xtro\a4galt, Xtro\a4gnt" "Mmus\A4gnt, Mmus\A4galt" "Hsap\A4GNT, Hsap\A4GALT" viable FBgn0264560 garz gartenzwerg http://flybase.org/reports/FBgn0264560 protein_coding_gene "ARF guanyl-nucleotide exchange factor activity ; GO:0005086 | inferred from genetic interaction with Arf79F, ArfGAP1" "regulation of ARF protein signal transduction ; GO:0032012 | inferred from electronic annotation with InterPro:IPR000904 Golgi organization ; GO:0007030 | inferred from mutant phenotype regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype regulation of ARF protein signal transduction ; GO:0032012 | inferred by curator from GO:0005086 salivary gland development ; GO:0007431 | inferred from direct assay regulation of GTPase activity ; GO:0043087 | inferred from genetic interaction with Arf79F epithelial cell development ; GO:0002064 | inferred from direct assay secretion by cell ; GO:0032940 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from direct assay" cis-Golgi network ; GO:0005801 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000070561 Golgi cis cisterna ; GO:0000137 | inferred from direct assay "Garz, ARF1GEF, garz, GEF, CG8487, ang, ArfGEF, GBF1, CG 8487" "IPR032691:Guanine nucleotide exchange factor, N-terminal, IPR011989:Armadillo-like helical, IPR023394:Sec7 domain, alpha orthogonal bundle, IPR000904:Sec7 domain" CG8487 11-Aug-17 DroID_v2017_08 "Drer\gbf1, Drer\ncf4" "Scer\SEC7, Scer\GEA2, Scer\GEA1, Scer\RVS167" "Cele\bris-1, Cele\gbf-1" Xtro\gbf1 "Mmus\Ncf4, Mmus\Gbf1" "Hsap\GBF1, Hsap\NCF4" FBgn0005612 Sox14 Sox box protein 14 http://flybase.org/reports/FBgn0005612 FBgn0034949 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding, bending ; GO:0008301 | inferred from direct assay" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype regulation of neuron remodeling ; GO:1904799 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from genetic interaction with Mical metamorphosis ; GO:0007552 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from genetic interaction with Mical neuron remodeling ; GO:0016322 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from mutant phenotype "CG3090, CG17263, DSox14, SOXC, SOX60B, SOX14, Dsox-14, DSox60B, DSox-14, Sox14, sox14" IPR009071:High mobility group box domain CG3090 11-Aug-17 DroID_v2017_08 "Drer\sox11b, Drer\sox11a, Drer\sox4a, Drer\sox18, Drer\sox14, Drer\sox7, Drer\sox21b, Drer\sox4b, Drer\sox17, Drer\sox12" Scer\ROX1 "Cele\pop-1, Cele\sox-3, Cele\sox-2, Cele\sem-2" "Xtro\sox17a, Xtro\sox7, Xtro\sox17b.1, Xtro\sox21, Xtro\sox18, Xtro\sox14, Xtro\sox17b.2" "Mmus\Sox11, Mmus\Sox14, Mmus\Sox21, Mmus\Sox12, Mmus\Sox18, Mmus\Sox4, Mmus\Sox7, Mmus\Sox17" "Hsap\SOX12, Hsap\SOX11, Hsap\SOX14, Hsap\SOX21, Hsap\SOX4, Hsap\SOX17, Hsap\SOX7, Hsap\SOX18" " pupal stage , embryonic stage , embryonic stage | 8-24 hr , pupal stage | late , adult stage " " embryonic stage , larval stage | third instar " "lethal,decreased cell death,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,somatic clone,lethal - all die before end of pupal stage" "anterior pupal spiracle,adult abdomen,dendriteppk.1.9,dorsal multidendritic neuron ddaC,mesothoracic tergum,somatic clone,dendrite,dendriteBSC136),dendrite | somatic clone,dendriteor-BR11),dendrite221" DRSC04656 I -0.148463283 -2.172459054 0.219036488 0.534234455 -0.783993735 1.453511322 FBgn0040505 Alk Anaplastic lymphoma kinase http://flybase.org/reports/FBgn0040505 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002011, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from direct assay" transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from electronic annotation with InterPro:IPR002011 positive regulation of MAPK cascade ; GO:0043410 | inferred from mutant phenotype regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from mutant phenotype visceral muscle development ; GO:0007522 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype digestive tract development ; GO:0048565 | inferred from mutant phenotype regulation of growth ; GO:0040008 | inferred from mutant phenotype activation of MAPKK activity ; GO:0000186 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000998, InterPro:IPR002011 type Ib terminal bouton ; GO:0061176 | inferred from direct assay subsynaptic reticulum ; GO:0071212 | inferred from direct assay type Is terminal bouton ; GO:0061177 | inferred from direct assay" "ALK, mili, DAlk, dALK, DAlk53, CG8250, Alk, alk, dAlk" "IPR000719:Protein kinase domain, IPR000998:MAM domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR002011:Tyrosine-protein kinase, receptor class II, conserved site, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG8250 11-Aug-17 DroID_v2017_08 "Drer\alk, Drer\mst1ra, Drer\met, Drer\lmtk2, Drer\ros1, Drer\mst1rb, Drer\ltk" Scer\SCH9 "Cele\F09A5.2, Cele\scd-2" "Xtro\ltk, Xtro\mst1r, Xtro\met" "Mmus\Ltk, Mmus\Lmtk2, Mmus\Insrr, Mmus\Alk, Mmus\Met, Mmus\Mst1r" "Hsap\LMTK2, Hsap\MST1R, Hsap\LTK, Hsap\ALK, Hsap\MET, Hsap\INSRR" "lethal,heat sensitive,neurophysiology defective,neuroanatomy defective,somatic clone,recessive,locomotor rhythm defective,cell migration defective,increased cell death,size defective,decreased cell size,learning defective,viable,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during pupal stage,increased cell size" "midgut,embryonic/larval gut | first instar larval stage,visceral mesoderm,embryonic myoblast,muscle founder cell,axon & photoreceptor cell R8 | somatic clone,optic cartridge,somatic clone,embryonic/larval digestive system,embryonic/larval midgut,neuromuscular junction,longitudinal visceral muscle primordium,muscle founder cell & visceral muscle primordium | ectopic,muscle founder cell & visceral muscle primordium,embryonic somatic muscle,ectopic,muscle founder cell & circular visceral muscle primordium,hemocyte,wing,muscle founder cell & visceral mesodermtwi.PG,embryonic visceral muscle,lamellocyte,wing disc,muscle founder cell & visceral muscle primordiumtwi.2PE,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0028991 seq sequoia http://flybase.org/reports/FBgn0028991 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "branching involved in open tracheal system development ; GO:0060446 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype R8 cell development ; GO:0045463 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | traceable author statement neuron development ; GO:0048666 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from mutant phenotype terminal cell fate specification, open tracheal system ; GO:0035154 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype" nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CG4055, 49Fc, vr5, l(2)49Fc, l(2)vr5, CG17724b, CG4037, CG32904, seq, 2R5, Seq" IPR013087:Zinc finger C2H2-type CG32904 11-Aug-17 DroID_v2017_08 "Drer\kdm4b, Drer\kdm4c, Drer\kdm4ab, Drer\kdm4aa" "Scer\GIS1, Scer\RPH1" - "Xtro\kdm4a, Xtro\kdm4b, Xtro\kdm4c" "Mmus\Kdm4c, Mmus\Kdm4b, Mmus\Kdm4d, Mmus\Kdm4a" "Hsap\KDM4E, Hsap\KDM4A, Hsap\KDM4C, Hsap\KDM4D" embryonic stage | stage 3-16 nervous system

" embryonic stage | stage 3-16 , adult stage " " nervous system && neuron && thecogen cell

, head && neuron

" "neuroanatomy defective,somatic clone,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,non-suppressor of variegation,dominant" "photoreceptor cell R7,somatic clone,photoreceptor cell R8,medulla layer M6,medulla layer M1,medulla layer M2,medulla layer M3,embryonic/larval ganglionic branch,dendrite | dorsal | embryonic stage,embryonic peripheral nervous system & multidendritic neuron,embryonic peripheral nervous system & multidendritic neuron | supernumerary,embryonic peripheral nervous system & multidendritic dendrite | ectopic,embryonic peripheral nervous system & axon,embryonic central nervous system & axon,embryonic peripheral nervous system & sensory neuron,motor neuron & axon & embryo,mesothoracic tergum & adult peripheral nervous system & sensory neuron | somatic clone,scutellum & adult peripheral nervous system & sensory neuron | somatic clone,photoreceptor cell & axon | somatic clone,presumptive embryonic/larval peripheral nervous system,dorsal,axon | dorsal | embryonic stage,chordotonal organ & neuron & embryo,axon & embryonic central nervous system,dendrite | embryonic stage | lateral,multidendritic neuron & dendrite & embryo,chaeta,socket,photoreceptor cell R7 | pupal stage,growth cone | pupal stageGMR.long,photoreceptor cell R8 | pupal stage,photoreceptor cell R8 | adult stage,medulla layer M6 | pupal stage,medulla layer M6 | adult stage,medulla layer M3 | pupal stage,medulla layer M3 | adult stage" FBgn0261560 Thor Thor http://flybase.org/reports/FBgn0261560 protein_coding_gene eukaryotic initiation factor 4E binding ; GO:0008190 | inferred from direct assay eukaryotic initiation factor 4E binding ; GO:0008190 | inferred from physical interaction with eIF4E1 inferred from physical interaction with eIF4E4 inferred from physical interaction with eIF4E5 inferred from physical interaction with eIF4E7 inferred from physical interaction with eIF4E3 eukaryotic initiation factor 4E binding ; GO:0008190 | inferred from sequence or structural similarity with HGNC:3288 negative regulation of translational initiation ; GO:0045947 | inferred from biological aspect of ancestor with PANTHER:PTN000292586 somatic muscle development ; GO:0007525 | inferred from mutant phenotype antibacterial humoral response ; GO:0019731 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from direct assay triglyceride metabolic process ; GO:0006641 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from direct assay immune response ; GO:0006955 | inferred from expression pattern inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | traceable author statement response to starvation ; GO:0042594 | inferred from direct assay regulation of mitochondrial translation ; GO:0070129 | inferred from direct assay regulation of cell growth ; GO:0001558 | inferred from mutant phenotype inferred from genetic interaction with Akt1 inferred from genetic interaction with Pi3K92E cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000292586 "4E-BP, 153432_at, d4E-BP, Phas1, thor, CT8705, 4E-BP1, eIF4E-BP, CG8846, d4EBP, d4E-BP1, 4EBP, l(2)k07736, BcDNA.HL08053, pp20, Dm 4E-BP, l(2)k13517, anon-WO0172774.158, BcDNA:HL08053, Thor, 4eBP, 4ebp, 43-BP, 4e-bp, d4e-bp, l(2)06270, dthor, d4eBP, 4e-BP, Thor/EIF4EBP" IPR008606:Eukaryotic translation initiation factor 4E binding CG8846 11-Aug-17 DroID_v2017_08 "Drer\eif4ebp2, Drer\eif4ebp3l, Drer\eif4ebp3, Drer\eif4ebp1, Drer\gra" - - Xtro\eif4ebp2 "Mmus\Eif4ebp3, Mmus\Eif4ebp1, Mmus\Eif4ebp2" "Hsap\C8orf88, Hsap\EIF4EBP1, Hsap\EIF4EBP2, Hsap\EIF4EBP3" " adult stage && oogenesis stage , embryonic stage , embryonic stage -- adult stage , larval stage | third instar " " ovary

, embryonic central nervous system

, nurse cell

, testis

" FBgn0000405 CycB Cyclin B http://flybase.org/reports/FBgn0000405 - protein_coding_gene cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VDG2 "attachment of spindle microtubules to kinetochore ; GO:0008608 | inferred from mutant phenotype G2/M transition of mitotic cell cycle ; GO:0000086 | non-traceable author statement embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement cell separation after cytokinesis ; GO:0000920 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype mitotic chromosome movement towards spindle pole ; GO:0007079 | inferred from mutant phenotype attachment of spindle microtubules to kinetochore ; GO:0008608 | traceable author statement syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from genetic interaction with CycA, CycB3 regulation of chromatin binding ; GO:0035561 | inferred from genetic interaction with Orc2 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement chromosome, centromeric region ; GO:0000775 | traceable author statement spindle midzone ; GO:0051233 | inferred from direct assay mitotic spindle ; GO:0072686 | colocalizes_with inferred from direct assay spindle ; GO:0005819 | traceable author statement" "cycB, cyclin B, cyclinB, DmcycB, CG3510, cyc B, mAbF2F4, 2g, cyc-B, CycB, CYCB, Cyc B, 3510, Cycb, CYC-B, chr2R:18312808..18312907, cycb" "IPR004367:Cyclin, C-terminal domain, IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like" CG3510 11-Aug-17 DroID_v2017_08 "Drer\ccnb1l, Drer\ccnb3, Drer\si:ch211-132b12.8, Drer\ccng2, Drer\ccni2, Drer\ccnb1, Drer\ccni, Drer\ccnb2, Drer\ccng1" "Scer\CLB3, Scer\CLN2, Scer\CLB2, Scer\CLN1, Scer\CLB5, Scer\CLB1, Scer\CLB6, Scer\CLB4, Scer\CLN3" "Cele\cyb-3, Cele\T12C9.7, Cele\cyb-2.2, Cele\cyb-2.1, Cele\cyb-1" "Xtro\ccnb2, Xtro\ccng1, Xtro\ccni2, Xtro\ccnb1.2, Xtro\ccni, Xtro\LOC100487861, Xtro\ccnb1, Xtro\ccno, Xtro\ccng2, Xtro\ccnb3" "Mmus\Ccni, Mmus\Ccnb2, Mmus\Ccnb1, Mmus\Ccng1, Mmus\Ccnb3, Mmus\Ccng2, Mmus\Ccno" "Hsap\CNTD2, Hsap\CCNB2, Hsap\CCNI, Hsap\CCNG2, Hsap\CCNB3, Hsap\CCNO, Hsap\CCNB1, Hsap\CCNG1, Hsap\CCNI2" " embryonic stage | early , adult stage && oogenesis stage | stage S9,10 , embryonic stage , adult stage && oogenesis stage , adult stage && oogenesis stage | <= stage S7 , larval stage , adult stage | male , embryonic stage | gastrula , adult stage | female " "

posterior{ 0 nos* } , nurse cell

, epidermis

,

posterior{ 0 pum* } , germarium

,

posterior{ - vas* } , oocyte

, pole cell

, embryonic central nervous system

,

posterior{ 0 Bic-D* } ,

posterior{ 0 tud* } ,

posterior{ - capu* } , testis

,

posterior{ - stau* } , organism | posterior

,

posterior{ - spir* } ,

posterior{ 0 vls* } ,

,

posterior{ - osk* } " " embryonic stage , larval stage , embryonic stage | early , embryonic stage | syncytial blastoderm , embryonic stage | stage 13 " " peripheral nervous system

, imaginal disc

{ 0 cycA- } , larval brain

, embryonic central nervous system

, larval central nervous system

, embryonic nervous system

, central nervous system

,

{ 0 cycA- } " "viable,fertile,female sterile,recessive,male sterile,mitotic cell cycle defective,semidominant,meiotic cell cycle defective,wild-type,cytokinesis defective,maternal effect,partially lethal - majority die,some die during embryonic stage,female,lethal - all die before end of embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "cyst cell,onion stage spermatid & nucleus,onion stage spermatid & nuclear chromosome,ovary,larval outer optic anlage,kinetochore,pole cell,cell cycle,anaphase & condensed nuclear chromosome,mitotic anaphase,anaphase & condensed nuclear chromosome | maternal effect,cycle 6 embryo,maternal effect,cycle 7 embryo,cycle 8 embryo,cycle 9 embryo,cycle 10 embryo,cycle 11 embryo,mitotic interphase | maternal effect,mitotic prophase | maternal effect,mitotic metaphase | maternal effect,cycle 14 embryo,aster | embryonic cycle 5,aster | embryonic cycle 6,aster | embryonic cycle 7,energid,mitosis | embryonic stage | maternal effect,microtubule | embryonic cycle 9 | maternal effect,astral microtubule | embryonic cycle 9 | maternal effect,cycle 12 embryo,mitotic interphase | embryonic cycle 10,mitotic interphase | embryonic cycle 11,mitotic interphase | embryonic cycle 12,mitotic interphase | embryonic cycle 13,mitosis | embryonic cycle 10,mitosis | embryonic cycle 11,mitosis | embryonic cycle 12,mitosis | embryonic cycle 13,supernumerary,aster,interphase | maternal effect,female germline cell,embryonic abdominal segment,filzkorper,egg chamber & cell,egg chamber & mitotic cell cycle,spindle | embryonic stagemat.‘±Tub67C.THsimVP16,mitotic cell cycleprd.RG1,mitotic anaphaseprd.RG1,eye,wing,macrochaeta" FBgn0045482 Gr59b Gustatory receptor 59b http://flybase.org/reports/FBgn0045482 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity with Gr5a response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr59C1, CG13537, Gr59D3, CG30191, Gr59b, GR59C.2, GR59b" IPR013604:7TM chemoreceptor CG30191 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - FBgn0013556 l(3)ry16 lethal (3) ry16 http://flybase.org/reports/FBgn0013556 - gene - - - "l(3)16, l(3)ry16" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0015609 CadN Cadherin-N http://flybase.org/reports/FBgn0015609 "FBgn0002007, FBgn0019859" protein_coding_gene beta-catenin binding ; GO:0008013 | non-traceable author statement cadherin binding ; GO:0045296 | inferred from physical interaction with CadN cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from physical interaction with CadN receptor activity ; GO:0004872 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P18824-2 calcium ion binding ; GO:0005509 | inferred from direct assay R7 cell development ; GO:0045467 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from sequence or structural similarity homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay R8 cell development ; GO:0045463 | inferred from mutant phenotype negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from direct assay axon guidance ; GO:0007411 | inferred from genetic interaction with uzip axon guidance ; GO:0007411 | non-traceable author statement axon target recognition ; GO:0007412 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype axon extension involved in axon guidance ; GO:0048846 | inferred from mutant phenotype calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity with shg inferred from sequence or structural similarity with MGI:MGI:88355 inferred from physical interaction with arm inferred from physical interaction with α-Cat axonal fasciculation ; GO:0007413 | traceable author statement calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity regulation of axon extension involved in axon guidance ; GO:0048841 | inferred from mutant phenotype retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity cell-cell junction ; GO:0005911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with shg integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:88355 plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | traceable author statement axon ; GO:0030424 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay "Ncad, N-cad, N-Cad, S(DmcycE[JP])2.12, ncad, CT21941, DN-Cad, DN-cad, DN, l(2)36Da, B, D-cad, l(2)Bld, NCad, anon-EST:CL32, CG7100, CadN, DNcad, cad1, cadN, DNCad, DN-CAD, N-Cadh, NCAD, DN-CAd, n-cad, Cad-N, N-cadherin" "IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR001881:EGF-like calcium-binding domain, IPR002126:Cadherin, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR015919:Cadherin-like, IPR027397:Catenin binding domain, IPR009030:Growth factor receptor cysteine-rich domain, IPR000233:Cadherin, cytoplasmic domain, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR013783:Immunoglobulin-like fold, IPR020894:Cadherin conserved site" CG7100 11-Aug-17 DroID_v2017_08 "Drer\dchs2, Drer\dchs1a, Drer\fat1b, Drer\fat3a, Drer\dchs1b, Drer\si:ch211-186j3.6, Drer\fat1a, Drer\fat2, Drer\si:dkey-22o22.2, Drer\cdh23" - "Cele\hmr-1, Cele\cdh-4, Cele\cdh-12, Cele\cdh-7, Cele\cdh-1" "Xtro\dchs2, Xtro\fat1, Xtro\fat4, Xtro\LOC100493382" "Mmus\Dchs1, Mmus\Fat4, Mmus\Cdh2, Mmus\Cdh10, Mmus\Cdh23, Mmus\Cdh12, Mmus\Cdh24, Mmus\Cdh4, Mmus\Cdh18, Mmus\Cdh11, Mmus\Fat1, Mmus\Cdh5, Mmus\Cdh6, Mmus\Cdh20, Mmus\Cdh22, Mmus\Fat3, Mmus\Cdh7, Mmus\Cdh15, Mmus\Cdh19, Mmus\Cdh9, Mmus\Fat2, Mmus\Cdh8, Mmus\Cdhr3" "Hsap\CDH15, Hsap\CDHR3, Hsap\FAT3, Hsap\CDH23, Hsap\DLK2, Hsap\DCHS1, Hsap\FAT4, Hsap\DCHS2, Hsap\FAT2, Hsap\FAT1" " embryonic stage | stage 5 , embryonic stage , embryonic stage | stage >=11 , embryonic stage | stage >5 " " mesoderm anlage

, ventral nerve cord

, embryonic neuron

, mesoderm

" " embryonic stage , larval stage | third instar , embryonic stage | stage >=9 " " motor nerve

, neuropil

, neuron

, longitudinal connective

, mesoderm

, myoblast

, anterior commissure

, posterior commissure

, embryonic nervous system

, photoreceptor cell

, adult myoblast

" "neuroanatomy defective,somatic clone,optomotor response defective,viable,courtship behavior defective,male,uncoordinated,locomotor behavior defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die during embryonic stage,sterile,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die during larval stage,body size defective,cell polarity defective,visible" "antennal lobe glomerulus DL1,somatic clone,antennal lobe glomerulus DL3,antennal lobe glomerulus VM7,olfactory receptor neuron,medulla,photoreceptor cell R7,cone cell,lamina monopolar neuron,anterior commissure,presumptive embryonic/larval central nervous system,MP1 neuron,dMP2 neuron,MP1 tract,medulla layer M10,medulla layer M5,medulla layer M2,lamina monopolar neuron L5,antennal lobe glomerulus,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,eye photoreceptor cell & axon | somatic clone | cell autonomous,longitudinal connective,vMP2 neuron,antennal lobe glomerulus DA1,medullary intrinsic neuron Mi1,adult brain,photoreceptor cell R8,photoreceptor cell R4,lamina plexus,lateral longitudinal fascicle,medulla layer M6,medulla layer M3,photoreceptor cell,cell non-autonomous,primary pigment cell,ommatidium,ommatidial precursor cluster,eye photoreceptor cell,lamina,optic cartridge,mesothoracic tergum" FBgn0036342 CG11279 - http://flybase.org/reports/FBgn0036342 protein_coding_gene - - - "BcDNA:GM21080, CG11279" IPR019034:Uncharacterised protein family UPF0390 CG11279 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" FBgn0034008 CG8152 - http://flybase.org/reports/FBgn0034008 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8152 "IPR000467:G-patch domain, IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG8152 11-Aug-17 DroID_v2017_08 Drer\gpank1 - "Cele\ZK792.4, Cele\ZK1320.7" Xtro\gpank1 Mmus\Gpank1 Hsap\GPANK1 "viable,fertile" FBgn0031001 CG7884 - http://flybase.org/reports/FBgn0031001 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7884 - CG7884 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0020338 anon-62DEa anon-62DEa http://flybase.org/reports/FBgn0020338 - gene - - - "3C12, anon-62DEa" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0032296 CG6729 - http://flybase.org/reports/FBgn0032296 protein_coding_gene - "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from sequence or structural similarity with UniProtKB:Q8no biological data available04" - CG6729 "IPR019354:Smg8/Smg9, IPR028802:Protein SMG8" CG6729 11-Aug-17 DroID_v2017_08 Drer\smg8 - Cele\smg-8 Xtro\smg8 Mmus\Smg8 Hsap\SMG8 DRSC22793 E -1.272567231 0.036046948 -0.907534642 -1.916433905 0.140404077 -0.877876221 FBgn0266064 GlyS Glycogen synthase http://flybase.org/reports/FBgn0266064 protein_coding_gene glycogen (starch) synthase activity ; GO:0004373 | inferred from direct assay glycogen biosynthetic process ; GO:0005978 | inferred from electronic annotation with InterPro:IPR008631 glycophagy ; GO:0061723 | inferred from mutant phenotype positive regulation of glycogen catabolic process ; GO:0045819 | inferred from mutant phenotype cellular response to sucrose stimulus ; GO:0071329 | inferred from direct assay glycogen metabolic process ; GO:0005977 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype response to sucrose ; GO:0009744 | inferred from mutant phenotype - "GlyS, CG6904, dGS, GS, CG6940, anon-WO0118547.108, Glys" IPR008631:Glycogen synthase CG6904 11-Aug-17 DroID_v2017_08 "Drer\gys1, Drer\gys2" "Scer\GSY2, Scer\GSY1" Cele\gsy-1 Xtro\gys1 "Mmus\Gys1, Mmus\Gys2" "Hsap\GYS2, Hsap\GYS1" FBgn0065585 l(2)SH0912 lethal (2) SH0912 http://flybase.org/reports/FBgn0065585 gene - - - "l(2)SH0912, l(2)SH2 0912" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0000479 dnc dunce http://flybase.org/reports/FBgn0000479 "FBgn0024972, FBgn0029653, FBgn0029654, FBgn0029655, FBgn0052498" protein_coding_gene "3',5'-cyclic-AMP phosphodiesterase activity ; GO:0004115 | inferred from sequence or structural similarity with SGD:S000005887" olfactory learning ; GO:0008355 | traceable author statement reproduction ; GO:0000003 | non-traceable author statement associative learning ; GO:0008306 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement learning or memory ; GO:0007611 | non-traceable author statement thermosensory behavior ; GO:0040040 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | non-traceable author statement regulation of protein kinase A signaling ; GO:0010738 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype cAMP-mediated signaling ; GO:0019933 | non-traceable author statement courtship behavior ; GO:0007619 | traceable author statement circadian rhythm ; GO:0007623 | traceable author statement nonassociative learning ; GO:0046958 | traceable author statement anesthesia-resistant memory ; GO:0007615 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype associative learning ; GO:0008306 | traceable author statement learning ; GO:0007612 | non-traceable author statement short-term memory ; GO:0007614 | inferred from mutant phenotype conditioned taste aversion ; GO:0001661 | inferred from mutant phenotype memory ; GO:0007613 | traceable author statement learning ; GO:0007612 | inferred from mutant phenotype mating behavior ; GO:0007617 | traceable author statement behavioral response to ethanol ; GO:0048149 | non-traceable author statement axon extension ; GO:0048675 | inferred from mutant phenotype cAMP-mediated signaling ; GO:0019933 | inferred from sequence or structural similarity with SGD:S000005887 - "dnc, CG32498, PDE4, CG10797, CG10791, EG:140G11.4, EG:96G10.7, fs(1)M42, EG:BACN05I09.3, EG:BACN5I9.2, CG14267, CG14268, CG10792, PDEII, dunce, DNC, PDE" "IPR002073:3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR023088:3'5'-cyclic nucleotide phosphodiesterase, IPR023174:3'5'-cyclic nucleotide phosphodiesterase, conserved site" CG32498 11-Aug-17 DroID_v2017_08 "Drer\pde6b, Drer\pde9al, Drer\si:dkey-219c10.4, Drer\pde4ca, Drer\pde11al, Drer\pde2a, Drer\pde5ab, Drer\pde5aa, Drer\crtc1b, Drer\LOC571737, Drer\pde9a, Drer\pde10a, Drer\pde7a, Drer\pde4bb, Drer\pde11a, Drer\pde6a, Drer\pde4a, Drer\pde6c, Drer\pde4d, Drer\pde4ba" Scer\PDE2 "Cele\pde-4, Cele\pde-6" "Xtro\pde6a, Xtro\pde2a, Xtro\pde11a, Xtro\pde4c, Xtro\pde4d, Xtro\pde4b, Xtro\pde7b, Xtro\pde7a, Xtro\LOC100493061, Xtro\pde10a, Xtro\pde4a, Xtro\pde6b, Xtro\pde9a, Xtro\pde5a, Xtro\pde6c" "Mmus\Pde9a, Mmus\Pde4a, Mmus\Pde6b, Mmus\Pde7b, Mmus\Pde6c, Mmus\Pde4d, Mmus\Pde10a, Mmus\Pde6a, Mmus\Pde2a, Mmus\Pde11a, Mmus\Pde4c, Mmus\Pde8b, Mmus\Pde5a, Mmus\Pde4b, Mmus\Pde8a, Mmus\Pde7a" "Hsap\PDE11A, Hsap\PDE7A, Hsap\PDE8A, Hsap\PDE6C, Hsap\PDE6A, Hsap\PDE8B, Hsap\PDE9A, Hsap\PDE10A, Hsap\PDE4B, Hsap\PDE7B, Hsap\PDE4D, Hsap\PDE4A, Hsap\PDE6B, Hsap\PDE4C, Hsap\PDE2A, Hsap\PDE5A" adult stage " mushroom body

, mushroom body

" " adult stage , larval stage | third instar " " neuropil

, calyx of mushroom body

, subesophageal ganglion

, nodulus

, mushroom body

, mushroom body gamma-lobe

, protocerebrum

, lobula

, ellipsoid body

, medulla

, antennal lobe

, fan shaped body

, pedunculus

, lobula plate neuropil

" "viable,fertile,courtship behavior defective,smell perception defective,memory defective,learning defective,semidominant,neuroanatomy defective,neurophysiology defective,chemical sensitive,recessive,behavior defective,optomotor response defective,visual behavior defective,thermotaxis behavior defective,locomotor rhythm defective,partially lethal - majority die,female sterile,female fertile,starvation stress response defective,tarsal response defective,sleep defective,sterile,short lived,female,visible,circadian rhythm defective,some die during pupal stage" "synapse | ectopic,glomerulus,aCC neuron,RP2 motor neuron,neuromuscular junction,larval brain & neuron,mushroom body & neuron,muscle fiber,neuron,adult brain,axon & motor neuron,varicosity | third instar larval stage,neuromuscular junction | third instar larval stage,nurse cell,dorsal appendage,egg chamber,embryonic/larval somatic muscle,nurse cell & nucleusN-64i16),supernumerary,nurse cell & nucleus,synapse,postsynaptic membrane,RP3 neuron & postsynaptic membrane,RP3 neuron & synaptic vesicle,RP3 motor neuron,motor neuron,multidendritic neuron,embryonic/larval neuromuscular junction,growth cone & embryonic neuron,cell body & embryonic neuron,nurse cell & nucleus | germ-line clone,wing,neuromuscular junction | larval stageD42,neuromuscular junction & abdominal 4 ventral longitudinal muscle 4 & larvaD42,neuromuscular junction & abdominal 4 ventral longitudinal muscle 3 & larvaD42,neuromuscular junction & abdominal ventral longitudinal muscle 1 & larvaD42,neuromuscular junction & abdominal ventral longitudinal muscle 2 & larvaD42,neuromuscular junctionD42,dense body,synapseD42,embryonic/larval neuromuscular junction | third instar larval stage,type II bouton | third instar larval stage,mesothoracic tergum,chaeta" DRSC17759 E 0.1639707 -1.39289055 -2.16408386 -0.98813988 1.387327623 0.433385792 FBgn0027066 Eb1 Eb1 http://flybase.org/reports/FBgn0027066 FBgn0010578 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR004953, InterPro:IPR027328 protein binding ; GO:0005515 | inferred from physical interaction with dia protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O77291 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A microtubule binding ; GO:0008017 | traceable author statement" microtubule-based process ; GO:0007017 | traceable author statement wound healing ; GO:0042060 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from mutant phenotype mitotic spindle elongation ; GO:0000022 | inferred from direct assay mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from direct assay pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from direct assay chromosome segregation ; GO:0007059 | inferred from direct assay mitotic spindle organization ; GO:0007052 | traceable author statement microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity establishment of mitotic spindle localization ; GO:0040001 | traceable author statement melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity microtubule plus-end ; GO:0035371 | colocalizes_with inferred from direct assay spindle microtubule ; GO:0005876 | colocalizes_with inferred from direct assay cytoplasmic microtubule ; GO:0005881 | colocalizes_with inferred from direct assay "EB1, Dm EB1, CG3265, dEB1, S(DmcycE[JP])2.5, dEb1, EB-1, dEB-1, l(2)04524, BcDNA.LD08743, l(2)4524, clone 2.52, clone 2.33, anon-EST:Liang-2.52, anon-EST:Liang-2.33, BcDNA:LD08743, Eb1, DmEB1, eb1, dmEB1" "IPR001715:Calponin homology domain, IPR004953:EB1, C-terminal, IPR027328:Microtubule-associated protein RP/EB, IPR027738:EB3, vertebrate" CG3265 11-Aug-17 DroID_v2017_08 "Drer\mapre2, Drer\mapre1b, Drer\mapre3b, Drer\mapre3a, Drer\mapre1a" Scer\BIM1 "Cele\ebp-2, Cele\ebp-3, Cele\ebp-1" Xtro\mapre1 "Mmus\Mapre2, Mmus\Mapre1, Mmus\Mapre3" "Hsap\MAPRE1, Hsap\MAPRE2, Hsap\MAPRE3" larval stage | third instar tendon cell

"partially lethal - majority die,lethal,recessive,neuroanatomy defective,uncoordinated,neurophysiology defective,lethal - all die before end of P-stage,some die during pharate adult stage,flightless,visible,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,wound healing defective,viable,immune response defective" "S2 cell-line,cytoplasmic microtubule,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,spindle & syncytial blastoderm embryo | maternal effect,nucleus & syncytial blastoderm embryo | maternal effect,macrochaeta,axon,microtubule,Johnston organ,Wheeler's organ,wing,spindle microtubule & astral microtubule,mitotic prophase,mitotic metaphase,mitotic telophase,spindle,epithelial cell,trichogen cell,axonelav.PLu,microtubuleelav.PLu" FBgn0035621 CG10591 - http://flybase.org/reports/FBgn0035621 protein_coding_gene - - - CG10591 - CG10591 11-Aug-17 DroID_v2017_08 - - Cele\col-101 - - - "partially lethal - majority die,some die during pupal stage" DRSC27468 K 0.56726997 0.09106826 0.019164002 -0.092013076 -0.821289776 -1.607242857 FBgn0002973 numb numb http://flybase.org/reports/FBgn0002973 "FBgn0010532, FBgn0010684" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VDG2 protein binding ; GO:0005515 | inferred from physical interaction with mol protein binding ; GO:0005515 | inferred from physical interaction with Nak Notch binding ; GO:0005112 | traceable author statement glial cell migration ; GO:0008347 | inferred from mutant phenotype ventral cord development ; GO:0007419 | non-traceable author statement regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | traceable author statement positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | traceable author statement regulation of Notch signaling pathway ; GO:0008593 | traceable author statement asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | traceable author statement neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype regulation of asymmetric cell division ; GO:0009786 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement central nervous system development ; GO:0007417 | traceable author statement cell fate determination ; GO:0001709 | non-traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement embryonic heart tube development ; GO:0035050 | inferred from genetic interaction with jumu inferred from genetic interaction with CHES-1-like neuroblast fate determination ; GO:0007400 | non-traceable author statement muscle cell fate specification ; GO:0042694 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | traceable author statement asymmetric cell division ; GO:0008356 | non-traceable author statement asymmetric neuroblast division ; GO:0055059 | traceable author statement sensory organ precursor cell division ; GO:0045035 | inferred from mutant phenotype centrosome localization ; GO:0051642 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement cell fate commitment ; GO:0045165 | traceable author statement regulation of nervous system development ; GO:0051960 | inferred from mutant phenotype rhythmic behavior ; GO:0007622 | traceable author statement pericardial nephrocyte differentiation ; GO:0061320 | inferred from mutant phenotype Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype basal cortex ; GO:0045180 | non-traceable author statement cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement basal part of cell ; GO:0045178 | traceable author statement basal part of cell ; GO:0045178 | non-traceable author statement "numb, Numb, dNumb, CG3779, nb, N7-1, d-numb, l(2)3235, l(2)03235, l(2)s2201, Nb, numbs" "IPR006020:PTB/PI domain, IPR010449:NUMB domain, IPR011993:PH domain-like" CG3779 11-Aug-17 DroID_v2017_08 "Drer\numb, Drer\numbl" - Cele\num-1 "Xtro\numbl, Xtro\numb" "Mmus\Numb, Mmus\Numbl" "Hsap\NUMB, Hsap\NUMBL" " larval stage--adult stage , embryonic stage | 0-3 hr , embryonic stage | >=3 hr , adult stage | female , oogenesis stage && adult stage | female " ovary

" adult stage , embryonic stage | 3-17 hr , embryonic stage , embryonic stage | 0-5 hr " " external sensory organ precursor cell

, peripheral nervous system | restricted

, neuroblast

, sensory mother cell

, embryonic ganglion mother cell

" "neuroanatomy defective,viable,fertile,visible,lethal,cell death defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,tumorigenic,heat sensitive,somatic clone,some die during immature adult stage,flightless" "abdominal dorsal acute muscle,A1-7 dorsal oblique muscle 1,abdominal dorsal oblique muscle,hypodermal muscle of larval abdominal 9,,scutellar bristle,dMP2 neuron,multidendritic neuron,embryonic/larval pericardial cell,embryonic/larval somatic muscle,neuron,abdominal dorsal bipolar neuron dbp,dorsal multidendritic neuron,cardioblast,glial cell of the perineurium,Malpighian tubule tip cell,segment border muscle,abdominal 1 lateral adult muscle precursor cell,abdominal 2 lateral adult muscle precursor cell,abdominal 3 lateral adult muscle precursor cell,abdominal 4 lateral adult muscle precursor cell,abdominal 5 lateral adult muscle precursor cell,abdominal 6 lateral adult muscle precursor cell,abdominal 7 lateral adult muscle precursor cell,EW1 neuron,EW2 neuron,EW3 neuron,abdominal lateral longitudinal muscle,abdominal ventral acute muscle,abdominal lateral transverse muscle,dorsal oblique muscle,dorsal transverse muscle,dorsal acute muscle,abdominal 1 ventral adult muscle precursor cell,abdominal 2 ventral adult muscle precursor cell,abdominal 3 ventral adult muscle precursor cell,abdominal 4 ventral adult muscle precursor cell,abdominal 5 ventral adult muscle precursor cell,abdominal 6 ventral adult muscle precursor cell,abdominal 7 ventral adult muscle precursor cell,abdominal adult muscle precursor cell,abdominal 1 dorsal adult muscle precursor cell,abdominal 2 dorsal adult muscle precursor cell,abdominal 3 dorsal adult muscle precursor cell,abdominal 4 dorsal adult muscle precursor cell,abdominal 5 dorsal adult muscle precursor cell,abdominal 6 dorsal adult muscle precursor cell,abdominal 7 dorsal adult muscle precursor cell,abdominal segment border muscle,pericardial cell,prothoracic dorsal oblique muscle,mesothoracic dorsal oblique muscle,metathoracic dorsal oblique muscle,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle,RP2 motor neuron,RP2sib neuron,vMP2 neuron,U neuron,Usib neuron,EL neuron,chordotonal organ,thecogen cell,embryonic somatic muscle,presumptive embryonic/larval peripheral nervous system,abdominal ventral longitudinal muscle,RP3 motor neuron,RP1 motor neuron,A1-7 dorsal acute muscle 1,A1-7 dorsal oblique muscle 2,peripheral glial cell,spermatogonium,trichogen cell,tormogen cell,postorbital bristle,external sensory organ,eo neuron,scolopidial dendritic cap cell,scolopale cell,scolopidial neuron,microchaeta,macrochaeta,dorsal row,ventral row,interommatidial bristle,mechanosensory sensory organ,socket,chaeta,sensory neuron,external sensory organ precursor cell IIa,sense organ,ganglion mother cell GMC4-2a,pCC neuron,aCC neuron,ganglion mother cell GMC1-1a,ganglion mother cell,external sensory organ precursor cell IIb,embryonic heart cardioblast,dorsal abdominal da1,external sensory organ precursor cell I,centrosome,ventral nerve cord,embryonic/larval brain,bract,A-subperineurial glial cell,B-subperineurial glial cell of abdomen,lateral ventral subperineurial glial cell,embryonic Malpighian tubule,embryonic Malpighian tubule tip cell,trichome,wing sensillum,embryonic/larval neuron,wing,adult sense organ,scolopale cell |,abdominal ventral muscle,pericardial cell |,antenna,-P309,notal microchaeta,mesothoracic tergum,larval optic anlage,sensory mother cell,external sensory organ precursor cell IIIb,eo sensory structure" FBgn0044058 GTD74-61-3 GTD74-61-3 http://flybase.org/reports/FBgn0044058 gene - - - GTD74-61-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030097 CG12115 - http://flybase.org/reports/FBgn0030097 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:LP02922, CG12115" - CG12115 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,visible" mesothoracic tergum FBgn0002227 l(3)68Ag lethal (3) 68Ag http://flybase.org/reports/FBgn0002227 - gene - - - "l(3)68Ag', l(3)517, E, l(3)SG20, l(3)ds10, l(3)E, l(3)68Ag" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,visible,recessive,lethal,lethal - all die before end of larval stage,some die during larval stage" "wing,imaginal disc" FBgn0002557 longevity longevity http://flybase.org/reports/FBgn0002557 - gene - - - "longevity, lon" - - 11-Aug-17 DroID_v2017_08 - - - - - - "paralytic,recessive,lethal,some die during immature adult stage" FBgn0062703 EP1081 EP1081 http://flybase.org/reports/FBgn0062703 gene - - - "EP(2)1081, EP1081" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0005007 dimorphos dimorphos http://flybase.org/reports/FBgn0005007 - gene - - - "dm, dimorphos, di" - - 11-Aug-17 DroID_v2017_08 - - - - - - "wing,eye" FBgn0000499 dsh dishevelled http://flybase.org/reports/FBgn0000499 "FBgn0027244, FBgn0042225" protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from physical interaction with nkd protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q99MH6 Notch binding ; GO:0005112 | non-traceable author statement Notch binding ; GO:0005112 | inferred from physical interaction with N phosphatidic acid binding ; GO:0070300 | inferred from direct assay frizzled binding ; GO:0005109 | inferred from biological aspect of ancestor with PANTHER:PTN000093831 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z6W3 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q45VV3 "intracellular signal transduction=0035556 |... electronic annotation with InterPro:IPR000591 <> heart development=0007507 | traceable author statement <> establishment of planar polarity=0001736 | traceable author statement <> axon extension=0048675 |... mutant phenotype <> imaginal disc-derived wing hair organization=0035317 |... genetic interaction with ck inferred from genetic interaction with fz inferred from genetic interaction with Rok inferred from genetic interaction with zip <> establishment of thoracic bristle planar orientation=0048106 | traceable author statement <> heart development=0007507 | <> imaginal disc-derived wing hair organization=0035317 |... mutant phenotype <> somatic stem cell population maintenance=0035019 |... mutant phenotype <> positive regulation of axon extension=0045773 |... genetic interaction with DAAM <> sensory organ development=0007423 | <> cell migration=0016477 |... mutant phenotype <> oogenesis=0048477 | traceable author statement <> wing and notum subfield formation=0035309 |... mutant phenotype <> establishment of tissue polarity=0007164 | <> ommatidial rotation=0016318 | <> Wnt signaling pathway, planar cell polarity pathway=0060071 |... biological aspect of ancestor with PANTHER:PTN000093831 <> establishment of imaginal disc-derived wing hair orientation=0001737 |... mutant phenotype <> ovarian follicle cell development=0030707 |... mutant phenotype <> Wnt signaling pathway=0016055 | <> female gonad development=0008585 |... mutant phenotype <> establishment of ommatidial planar polarity=0042067 |... mutant phenotype <> salivary gland morphogenesis=0007435 |... mutant phenotype <> Wnt signaling pathway=0016055 | traceable author statement <> heart formation=0060914 |... mutant phenotype <> regulation of tube length, open tracheal system=0035159 |... mutant phenotype <> epidermis morphogenesis=0048730 |... mutant phenotype <> establishment of mitotic spindle orientation=0000132 |... direct assay inferred from mutant phenotype <> regulation of actin filament bundle assembly=0032231 |... genetic interaction with Rok <> dorsal closure=0007391 |... mutant phenotype <> Wnt signaling pathway=0016055 |... mutant phenotype <> retinal ganglion cell axon guidance=0031290 |... mutant phenotype <> imaginal disc-derived leg joint morphogenesis=0016348 |... mutant phenotype <> establishment of tissue polarity=0007164 | traceable author statement <> dorsal closure=0007391 | traceable author statement <> regulation of compound eye pigmentation=0048076 |... mutant phenotype <> compound eye morphogenesis=0001745 |... mutant phenotype <> positive regulation of axon guidance=1902669 |... mutant phenotype <> negative regulation of heart induction by canonical Wnt signaling pathway=0003136 |... mutant phenotype <> imaginal disc-derived wing morphogenesis=0007476 | traceable author statement <> border follicle cell migration=0007298 |... mutant phenotype <> establishment of epithelial cell planar polarity=0090163 |... mutant phenotype <> establishment of epithelial cell apical/basal polarity=0045198 |... mutant phenotype <> motor neuron axon guidance=0008045 |... mutant phenotype <> establishment of ommatidial planar polarity=0042067 |... genetic interaction with fz <> dorsal closure, elongation of leading edge cells=0007394 |... mutant phenotype <> filopodium assembly=0046847 |... mutant phenotype <> synaptic target inhibition=0016201 |... mutant phenotype <> axon guidance=0007411 |... mutant phenotype <> oogenesis=0048477 |... mutant phenotype <> protein localization=0008104 | traceable author statement <> R3/R4 cell fate commitment=0007464 | <> negative regulation of Notch signaling pathway=0045746 |... mutant phenotype <> lamellipodium assembly=0030032 |... mutant phenotype" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000093945 plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay adherens junction ; GO:0005912 | traceable author statement "Dsh, DSH, l(1)10Bd, l(1)dsh, l(1)G0267, l(1)G17, CG1720, CG18361, dsh, Dvl, Dm Dsh, dishevelled" "IPR000591:DEP domain, IPR001158:DIX domain, IPR001478:PDZ domain, IPR003351:Dishevelled protein domain, IPR008339:Dishevelled family, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR015506:Dishevelled-related protein, IPR026542:Dishevelled Dsh, IPR029071:Ubiquitin-related domain" CG18361 11-Aug-17 DroID_v2017_08 "Drer\dvl2, Drer\dvl3, Drer\dvl1a, Drer\dvl1b" - "Cele\dsh-2, Cele\dsh-1, Cele\mig-5" "Xtro\dvl2, Xtro\dvl1, Xtro\dvl3" "Mmus\Dvl1, Mmus\Dixdc1, Mmus\Dvl2, Mmus\Dvl3" "Hsap\DVL3, Hsap\DVL1, Hsap\DVL2" " embryonic stage -- adult stage , adult stage && oogenesis stage , larval stage , embryonic stage | stage 11 , embryonic stage | early , embryonic stage " " egg chamber

, imaginal disc

,

ubiquitous " "lethal,some die during pupal stage,partially lethal - majority die,visible,lethal - all die before end of pupal stage,viable,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,planar polarity defective,heat sensitive,cell polarity defective,dominant,wild-type,lethal - all die before end of larval stage,rescuable maternal effect,some die during larval stage,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,cell death defective,somatic clone,fertile,cell autonomous,partially lethal - majority live,female sterile,male,male fertile,cell non-autonomous,germline clone,segment polarity phenotype" "filzkorper,eye,wing vein,eye photoreceptor cell,ommatidium,denticle belt,embryonic/first instar larval cuticle,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,germline clone,follicle cell,somatic clone,microchaeta,supernumerary,heat sensitive,macrochaeta & wing,sensory mother cell,wing hair,adult,wing,antenna,scutum,pronotum,photoreceptor cell R4,cephalopharyngeal skeleton,adult thorax,dorsal,primordium of embryonic/larval spiracle,posterior,fronto-orbital plate,frons,leg,dorsal cluster neuron,medulla,axon & dorsal cluster neuron,follicle stem cell,lamina,neuron,ovary,germarium,egg chamber,ovarian sheath,triple row,tarsal segment 1 & joint,tarsal segment 2 & joint,tarsal segment 3,tarsal segment 4,embryonic/larval dorsal vessel,wing hinge,axillary pouch,yellow club,pleural wing process,pleural wing sclerite,precursor,macrochaeta,embryonic epidermis,wing sensillum,ectopic,chaeta,trichome,leg & joint,joint,mesothoracic tergum & trichome,external sensory organ precursor cell I,cell autonomous,prothoracic femoral bract,prothoracic tibial bract,mesothoracic femoral bract,mesothoracic tibial bract,metathoracic femoral bract,metathoracic tibial bract,interommatidial bristle,adult thorax & microchaeta,embryonic/larval dorsal trunk,dorsal wing blade,anterior,border follicle cell,class IV dendritic arborizing neuron,cell non-autonomous,wing margin bristle,stomodeal invagination,embryonic/larval tracheal system,wing & macrochaeta,photoreceptor cell,eye disc,maternal effect,embryonic dorsal epidermis,embryonic leading edge cell,ventral,wing & triple row | somatic clone,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 8 ventral denticle belt,embryonic head,midgut constriction 2,embryonic leading edge cell & filopodium,embryonic leading edge cell & actin filament,embryonic leading edge cell & microtubule,amnioserosa,ocellus,adult cuticle,adult head,dorsal margin photoreceptor,medial triple row,pigment cell,ventral thoracic disc,secondary pigment cell,tertiary pigment cell,denticle,embryonic ventral epidermis,embryo,presumptive embryonic salivary gland,interfollicle cell,macrochaeta & scutellumptc-559.1,microchaeta & scutellumptc-559.1,wing hair & 1st posterior cellptc-559.1,microchaeta & scutumrho-rhl,morphogenetic furrow,sensory mother cell & dorsal mesothoracic disc | ectopicsd-SG29.1,wing disc,dorsal cluster neuron | adult stage,medulla | adult stage" FBgn0001122 Galphao G protein alpha o subunit http://flybase.org/reports/FBgn0001122 FBgn0026838 protein_coding_gene GTP binding ; GO:0005525 | inferred from direct assay G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 protein binding ; GO:0005515 | inferred from physical interaction with Dhit GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 sensory perception of sweet taste ; GO:0050916 | inferred from mutant phenotype cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 asymmetric cell division ; GO:0008356 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype establishment of endothelial blood-brain barrier ; GO:0014045 | inferred from mutant phenotype behavioral response to starvation ; GO:0042595 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype calcium-mediated signaling ; GO:0019722 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype axon ensheathment in central nervous system ; GO:0032291 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay heterotrimeric G-protein complex ; GO:0005834 | inferred from direct assay "Go, Galpha47A, Galphao47A, Galphao, Galpha[[0]], Galpha[[o]], Bkh, Galpha[[047A]], Go-alpha, bkh, Goa, DROGPAD, Goalpha, G[[o]]alpha, alpha(o), dgoalpha, dgo, G[[oalpha]], DG[[o]], DGalpha[[o]], G-oalpha47A, G-alpha-47A, DGalpha0, CG2204, G-oalpha, Goalpha47a, G(o)alpha47A, G[[o]], like GNAO, goalpha, G-oalpha47a, drogpad, Galpha[[o]]47A, Galphai/o" "IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR001408:G-protein alpha subunit, group I, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2204 11-Aug-17 DroID_v2017_08 "Drer\gnai2b, Drer\gnaia, Drer\gnav1, Drer\gna15.1, Drer\gnai1, Drer\gna14, Drer\gna15.2, Drer\gnat2, Drer\gna11a, Drer\gna12a, Drer\gnao1b, Drer\gnai3, Drer\gna13a, Drer\gnao1a, Drer\gnat1, Drer\gnaq, Drer\gna13b, Drer\gnai2a, Drer\gnaz, Drer\LOC797518" "Scer\GPA1, Scer\GPA2" "Cele\gpa-7, Cele\odr-3, Cele\gpa-1, Cele\gpa-11, Cele\goa-1, Cele\gpa-2, Cele\gpa-10, Cele\gpa-8, Cele\gpa-6, Cele\gpa-4, Cele\egl-30, Cele\gpa-16, Cele\gpa-3" "Xtro\gnai1, Xtro\gna11, Xtro\gnao1, Xtro\gna14, Xtro\gna13, Xtro\gnat2, Xtro\gnai2, Xtro\gnat1, Xtro\gna15, Xtro\gnai3, Xtro\gnaq" "Mmus\Gna15, Mmus\Gnai2, Mmus\Gna11, Mmus\Gnaq, Mmus\Gna14, Mmus\Gnat2, Mmus\Gnaz, Mmus\Gnat3, Mmus\Gnat1, Mmus\Gnai1, Mmus\Gnai3, Mmus\Gna13, Mmus\Gna12, Mmus\Gnao1" "Hsap\GNA12, Hsap\GNAI3, Hsap\GNAO1, Hsap\GNA14, Hsap\GNAQ, Hsap\GNA11, Hsap\GNA15, Hsap\GNAT2, Hsap\GNAI2, Hsap\GNAT3, Hsap\GNAZ, Hsap\GNAT1, Hsap\GNA13, Hsap\GNAI1" " embryonic stage--pupal stage , embryonic stage | 0-2 hr , adult stage && oogenesis stage " " nurse cell

, oocyte

" " adult stage , embryonic stage | stage >=13 " " adult antennal nerve | restricted

, neuropil adult brain

, neuropil

, lamina | restricted

, adult brain cortex

, neuropil thoracic ganglion

, ocellar nerve | proximal

" "neurophysiology defective,taste perception defective,lethal,recessive,cell polarity defective,somatic clone,planar polarity defective,visible,cell non-autonomous,dominant,neuroanatomy defective,starvation stress response defective,wild-type,viable,circadian rhythm defective,mitotic cell cycle defective,heat sensitive,partially lethal - majority die,cell autonomous" "large labellar taste bristle,embryonic/larval visceral muscle,longitudinal connective,motor neuron,embryonic/larval dorsal vessel,wing,somatic clone,macrochaeta,socket,eo neuron,eo sensory structure,sensory organ cell,ectopic,wing margin,wing hair,supernumerary,wing margin bristle,cell non-autonomous,denticle belt,embryonic/first instar larval cuticle,neuroblast,embryonic/larval neuromuscular junction | third instar larval stage,type II bouton,supernumerary | third instar larval stage,type I bouton,medial triple row & socketpnr-MD237,medial triple row & eo neuronpnr-MD237,medial triple row & eo sensory structurepnr-MD237,medial triple row & sensory organ cellpnr-MD237,neuroblast & spindlemat.‘±Tub67C.THsimVP16,heat sensitive,cell autonomous,mechanosensory sensory organ,medial triple row,sensory mother cell,thecogen cell,eo glial cell,scolopidial neuron,nervous system" FBgn0000250 cact cactus http://flybase.org/reports/FBgn0000250 FBgn0013453 protein_coding_gene transcription factor binding ; GO:0008134 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VR99 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VEZ5 dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | traceable author statement innate immune response ; GO:0045087 | non-traceable author statement positive regulation of antifungal peptide biosynthetic process ; GO:0006967 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from expression pattern hemopoiesis ; GO:0030097 | traceable author statement dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype cytoplasmic sequestering of transcription factor ; GO:0042994 | inferred from sequence or structural similarity antifungal humoral response ; GO:0019732 | inferred from mutant phenotype defense response ; GO:0006952 | traceable author statement response to fungus ; GO:0009620 | traceable author statement immune response ; GO:0006955 | traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement cytoplasm ; GO:0005737 | traceable author statement neuromuscular junction ; GO:0031594 | inferred from direct assay "CACT, CG5848, dip6, n(2)k17003, BG:DS02740.15, cac, fs(2)ltoRN48, cact, Cact, 5848, Ikappa, NFkappabeta1A, Cactus" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG5848 11-Aug-17 DroID_v2017_08 "Drer\nfkbie, Drer\nfkbiaa, Drer\nfkbiab, Drer\nfkbib" - "Cele\shn-1, Cele\ikb-1, Cele\nfki-1" "Xtro\nfkbia, Xtro\nfkbie" "Mmus\Nfkbie, Mmus\Nfkbib, Mmus\Nfkbia" "Hsap\NFKBIA, Hsap\NFKBIB, Hsap\NFKBIE" " embryonic stage | early , adult stage | female , embryonic stage " embryonic stage | early

dorsal ventral gradient "wild-type,lethal,recessive,heat sensitive,visible,maternal effect,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,germline clone,non-rescuable maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,viable" "embryonic dorsal epidermis,heat sensitive,wing,wing vein,ectopic,embryonic epidermis,maternal effect,embryonic ventral epidermis,embryonic/first instar larval cuticle,ventral,denticle belt,filzkorper,embryo,dorsal,melanotic mass,embryonic/larval digestive system,lamellocyte,germline clone,hemocyte,embryonic/larval hemolymph,embryonic/larval lymph gland,embryonic/larval spiracle,gastrula embryo,cephalic furrow,amnioserosa,amnioproctodeal invagination,dorsal fold,extended germ band embryo,embryonic leading edge cell,embryonic/larval hemocyte,podocyte,dorsal appendage" DRSC03501 IE -1.50180946 -2.446172305 -0.725100161 -1.852532621 0.217396329 0.288300518 FBgn0051569 tRNA:Ala-AGC-2-5 transfer RNA:Alanine-AGC 2-5 http://flybase.org/reports/FBgn0051569 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna46-AlaAGC, tRNA:A:AGC:AE002708-j, tRNA:-?:90Cd, CR31569, tRNA[[Ala]], chr3R.trna52-AlaAGC, tRNA-Ala-AGC-2-5, tRNA:Ala-AGC-2-5, tRNA:CR31569, GCU" - CR31569 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001214 Hpb Hydroxyphenyl buten 1 http://flybase.org/reports/FBgn0001214 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - "HPB, Hpb" - - 11-Aug-17 DroID_v2017_08 - - - - - - smell perception defective FBgn0032388 CG6686 - http://flybase.org/reports/FBgn0032388 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:10538 "maturation of 5S rRNA ; GO:0000481 | inferred from biological aspect of ancestor with PANTHER:PTN000365724 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D spliceosomal snRNP assembly ; GO:0000387 | inferred from biological aspect of ancestor with PANTHER:PTN000365724 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from biological aspect of ancestor with PANTHER:PTN000365724 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000365724 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG6686, SART1" IPR005011:SNU66/SART1 family CG6686 11-Aug-17 DroID_v2017_08 Drer\sart1 Scer\SNU66 Cele\F19F10.9 Xtro\sart1 Mmus\Sart1 Hsap\SART1 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC02979 IE -0.47538527 3.598489137 0.494886636 2.224215305 -1.173148079 -1.233302986 FBgn0025724 beta'COP Coat Protein (coatomer) beta' http://flybase.org/reports/FBgn0025724 - protein_coding_gene structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR006692 "retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with SGD:S000003105 regulation of lipid storage ; GO:0010883 | inferred from direct assay retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000458798 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000458798 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000458798 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000458798" COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity with SGD:S000003105 Golgi stack ; GO:0005795 | inferred from direct assay COPI vesicle coat ; GO:0030126 | inferred from direct assay "beta'COP, dbeta'COP, CG6699, beta'-COP, beta'Cop, COPIbeta'" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR006692:Coatomer, WD associated region, IPR017986:WD40-repeat-containing domain, IPR016453:Coatomer beta' subunit (COPB2), IPR020472:G-protein beta WD-40 repeat, IPR011990:Tetratricopeptide-like helical domain, IPR011042:Six-bladed beta-propeller, TolB-like" CG6699 11-Aug-17 DroID_v2017_08 Drer\copb2 "Scer\COP1, Scer\SEC27" "Cele\copb-2, Cele\E03H4.8, Cele\Y41C4A.32" Xtro\copb2 Mmus\Copb2 "Hsap\COPA, Hsap\COPB2" "visible,viable" wing DRSC03492 IE -0.543055187 2.201882846 5.489816522 -3.135324545 -0.290984702 -0.720156747 FBgn0261602 RpL8 Ribosomal protein L8 http://flybase.org/reports/FBgn0261602 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002171, InterPro:IPR022666, InterPro:IPR022669, InterPro:IPR022671 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 insulin receptor signaling pathway ; GO:0008286 | inferred from genetic interaction with Pi3K92E inferred from genetic interaction with InR compound eye development ; GO:0048749 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement regulation of cell size ; GO:0008361 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "RpL8, CG1263, M(3)62F, L8, rpL8, anon-EST:Posey5, M(3)LS2, Rp L8, RPL8" "IPR002171:Ribosomal protein L2, IPR008991:Translation protein SH3-like domain, IPR012340:Nucleic acid-binding, OB-fold, IPR014726:Ribosomal protein L2, domain 3, IPR022666:Ribosomal Proteins L2, RNA binding domain, IPR022669:Ribosomal protein L2, C-terminal, IPR022671:Ribosomal protein L2, conserved site, IPR014722:Ribosomal protein L2 domain 2" CG1263 11-Aug-17 DroID_v2017_08 "Drer\rpl8, Drer\mrpl2" "Scer\RML2, Scer\RPL2A, Scer\RPL2B" "Cele\mrpl-2, Cele\rpl-2" Xtro\rpl8 "Mmus\Rpl8, Mmus\Mrpl2" "Hsap\RPL8, Hsap\MRPL2" " pupal stage , larval stage | third instar , adult stage | female , embryonic stage , adult stage | male " " embryonic/larval salivary gland

, ovary

, embryonic/larval fat body

" DRSC08695 EK -1.158285147 -0.863536354 -3.750090768 -4.55747933 0.497518724 3.633095475 FBgn0002524 lace lace http://flybase.org/reports/FBgn0002524 "FBgn0025294, FBgn0027869" protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839 serine C-palmitoyltransferase activity ; GO:0004758 | inferred from sequence or structural similarity serine C-palmitoyltransferase activity ; GO:0004758 | contributes_to inferred from direct assay regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype regulation of growth ; GO:0040008 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype regulation of cellular protein localization ; GO:1903827 | inferred from mutant phenotype sphingolipid biosynthetic process ; GO:0030148 | inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "lace, anon-EST:Posey289, CG4162, SPT-II, BG:DS01845.3, l(2)35Dc, l(2)br36, l35Dc, br36, Lace, SPT, dSpt2" "IPR001917:Aminotransferase, class-II, pyridoxal-phosphate binding site, IPR004839:Aminotransferase, class I/classII, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG4162 11-Aug-17 DroID_v2017_08 "Drer\sptlc3, Drer\sptlc2a, Drer\sptlc2b" Scer\LCB2 "Cele\sptl-2, Cele\sptl-3" "Xtro\sptlc2, Xtro\sptlc3" "Mmus\Sptlc3, Mmus\Sptlc2" "Hsap\SPTLC3, Hsap\SPTLC2" " embryonic stage , larval stage " "

ubiquitous , dorsal mesothoracic disc | ubiquitous

, sensory organ cell &&of embryonic head

, embryonic/larval midgut

, eye-antennal disc | ubiquitous

" "lethal,recessive,visible,developmental rate defective,lethal - all die before end of larval stage,nutrition conditional,some die during third instar larval stage,flight defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "wing,chaeta,eye,ommatidium,crossvein,ectopic,microchaeta,macrochaeta,leg,antenna,wing disc,eye-antennal disc,ventral thoracic disc,cone cell,primary pigment cell,secondary pigment cell,tertiary pigment cell,interommatidial bristle,embryonic head" DRSC03564 I 0.267362789 1.958663635 1.444810526 -0.844704537 0.200037154 0.942181366 FBgn0001624 dlg1 discs large 1 http://flybase.org/reports/FBgn0001624 "FBgn0010108, FBgn0027239, FBgn0027662, FBgn0028321, FBgn0029052, FBgn0030295, FBgn0066811, FBgn0066812, FBgn0066813" protein_coding_gene epidermal growth factor receptor binding ; GO:0005154 | traceable author statement ionotropic glutamate receptor binding ; GO:0035255 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 structural molecule activity ; GO:0005198 | traceable author statement guanylate kinase activity ; GO:0004385 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with gukh "synaptic growth at neuromuscular junction=0051124 |... mutant phenotype <> gravitaxis=0042332 |... mutant phenotype <> nervous system development=0007399 |... mutant phenotype <> cell fate specification=0001708 |... mutant phenotype <> septate junction assembly=0019991 | traceable author statement <> establishment or maintenance of epithelial cell apical/basal polarity=0045197 | traceable author statement <> establishment or maintenance of polarity of larval imaginal disc epithelium=0016336 | traceable author statement <> establishment or maintenance of epithelial cell apical/basal polarity=0045197 | <> dorsal closure=0007391 | traceable author statement <> basal protein localization=0045175 | <> mating behavior=0007617 |... mutant phenotype <> locomotor rhythm=0045475 |... mutant phenotype <> basal protein localization=0045175 |... mutant phenotype <> protein localization=0008104 | traceable author statement <> protein localization=0008104 |... mutant phenotype <> morphogenesis of an epithelium=0002009 | traceable author statement <> establishment or maintenance of polarity of embryonic epithelium=0016332 | traceable author statement <> behavioral response to ethanol=0048149 |... mutant phenotype <> ovarian follicle cell development=0030707 |... mutant phenotype <> regulation of border follicle cell delamination=0030710 | traceable author statement <> morphogenesis of larval imaginal disc epithelium=0016335 | traceable author statement <> regulation of JAK-STAT cascade=0046425 |... mutant phenotype <> asymmetric protein localization=0008105 |... mutant phenotype <> cell proliferation=0008283 | traceable author statement <> establishment of spindle orientation=0051294 |... mutant phenotype <> morphogenesis of follicular epithelium=0016333 |... mutant phenotype <> regulation of glucose metabolic process=0010906 |... mutant phenotype <> regulation of Notch signaling pathway=0008593 |... mutant phenotype <> regulation of epidermal growth factor receptor signaling pathway=0042058 |... mutant phenotype <> asymmetric protein localization=0008105 | traceable author statement <> cytoskeleton organization=0007010 | <> cell fate commitment involved in pattern specification=0060581 |... mutant phenotype <> establishment or maintenance of polarity of follicular epithelium=0016334 |... genetic interaction with l(2)gl <> positive regulation of synaptic growth at neuromuscular junction=0045887 |... mutant phenotype <> dorsal closure=0007391 | <> morphogenesis of a polarized epithelium=0001738 | traceable author statement <> positive phototaxis=0046956 |... mutant phenotype <> negative regulation of transcription from RNA polymerase II promoter=0000122 |... mutant phenotype <> anterior/posterior axis specification, follicular epithelium=0030714 |... mutant phenotype <> regulation of cell cycle=0051726 | <> receptor clustering=0043113 |... biological aspect of ancestor with PANTHER:PTN001501163 <> pole plasm protein localization=0007318 |... mutant phenotype <> establishment of mitotic spindle orientation=0000132 |... genetic interaction with Ran <> negative regulation of cell proliferation=0008285 | traceable author statement <> receptor localization to synapse=0097120 |... biological aspect of ancestor with PANTHER:PTN001501163 <> asymmetric protein localization involved in cell fate determination=0045167 | traceable author statement <> chemical synaptic transmission=0007268 |... mutant phenotype <> establishment or maintenance of polarity of larval imaginal disc epithelium=0016336 | <> establishment or maintenance of neuroblast polarity=0045196 | traceable author statement <> regulation of cell proliferation=0042127 | traceable author statement <> male courtship behavior=0008049 |... mutant phenotype" tricellular tight junction ; GO:0061689 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay septate junction ; GO:0005918 | traceable author statement membrane ; GO:0016020 | traceable author statement plasma membrane ; GO:0005886 | inferred from mutant phenotype type Ib terminal bouton ; GO:0061176 | inferred from direct assay presynaptic membrane ; GO:0042734 | colocalizes_with inferred from direct assay septate junction ; GO:0005918 | non-traceable author statement apicolateral plasma membrane ; GO:0016327 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay postsynaptic density ; GO:0014069 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 septate junction ; GO:0005918 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay synapse ; GO:0045202 | traceable author statement basolateral plasma membrane ; GO:0016323 | traceable author statement type I terminal bouton ; GO:0061174 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay postsynaptic membrane ; GO:0045211 | colocalizes_with inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay subsynaptic reticulum ; GO:0071212 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay smooth septate junction ; GO:0005920 | inferred from direct assay postsynaptic membrane ; GO:0045211 | inferred from direct assay ionotropic glutamate receptor complex ; GO:0008328 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001501163 perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay subsynaptic reticulum ; GO:0071212 | septate junction ; GO:0005918 | postsynaptic membrane ; GO:0045211 | neuromuscular junction ; GO:0031594 | "dlg, Dlg, DLG, Discs-large, Dlg-A, anon-EST:Posey93, Dlg1, dlg-A, misb, CG1725, DLG-A, DlgA, dlgA, dlg-1, Drodlg, l(1)dlg1, l(1)dlg, l(1)10Bf, l(1)d.lg-1, l(1)discs large, l(1)bwn, l(1)dlg-1, d. lg.-1, l(1)L11, 11, l(1)lpr-2, l(1)d.lg.-1, l(1)G0276, l(1)G0342, l(1)G0456, l(1)l.pr.-2, l(1)G19, CG1730, anon-WO03040301.258, anon-WO03040301.268, anon-WO03040301.260, dlg1, CPD, SAP97, PSD95, dlgS97, DLG1, DlgS97, PSD-95" "IPR001452:SH3 domain, IPR001478:PDZ domain, IPR004172:L27 domain, IPR008144:Guanylate kinase-like domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR015143:L27-1, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020590:Guanylate kinase, conserved site, IPR016313:Disks large 1" CG1725 11-Aug-17 DroID_v2017_08 "Drer\LOC100534780, Drer\dlg4b, Drer\dlg5a, Drer\dlg5b.1, Drer\dlg1, Drer\dlg4, Drer\dlg3, Drer\card11, Drer\dlg1l, Drer\LOC100537443, Drer\dlg2" - "Cele\dlg-1, Cele\F23C8.13" "Xtro\dlg5, Xtro\card14, Xtro\dlg2, Xtro\dlg3, Xtro\dlg4, Xtro\dlg1" "Mmus\Patj, Mmus\Dlg4, Mmus\Dlg1, Mmus\Dlg5, Mmus\Card10, Mmus\Card14, Mmus\Pdzd2, Mmus\Dlg2, Mmus\Dlg3" "Hsap\DLG2, Hsap\DLG5, Hsap\DLG3, Hsap\CARD10, Hsap\DLG1, Hsap\PDZD2, Hsap\PATJ, Hsap\CARD14, Hsap\DLG4" " larval stage , adult stage | male , spermatogenesis && adult stage , embryonic stage , adult stage && oogenesis stage , oogenesis stage && adult stage | female " " embryonic/larval proventriculus

, male accessory gland

, primary gonial cell

, testis

, ventral nerve cord

, embryonic/larval digestive system

, peripheral nervous system

, optic lobe

, nurse cell

, larval brain

, oogonial cell

, follicle cell

, epidermis

, embryonic brain

, ejaculatory bulb

, embryonic/larval salivary gland

, imaginal disc

" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,somatic clone,viable,neurophysiology defective,some die during third instar larval stage,phototaxis defective,locomotor rhythm defective,courtship behavior defective,mating defective,gravitaxis defective,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive,neuroanatomy defective,hyperplasia,lethal - all die before end of P-stage,some die during pharate adult stage,polyphasic,tumorigenic,flightless,cell polarity defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,partially lethal - majority die,flight defective,locomotor behavior defective" "embryo,germline clone,eye,somatic clone,eye disc,wing,wing margin,imaginal disc,embryonic/larval brain,presynaptic membrane & neuromuscular junction | larval stage,border follicle cell,follicle cell,heat sensitive,postsynaptic membrane,wing disc,ring gland,bouton,external sensory organ precursor cell I,macrochaeta,interommatidial bristle,antenna,leg,embryonic/larval optic lobe,prothoracic leg disc,mesothoracic leg disc,neuromuscular junction,neuromuscular junction & bouton,neuromuscular junction & postsynaptic membrane,NMJ bouton,subsynaptic reticulum,ventral nerve cord,neuromuscular junction | larval stage,postsynaptic membrane & neuromuscular junction | larval stage,adherens junction,socket,brain,type I bouton & synaptic vesicle & third instar larvaN71),synapse | third instar larval stageN71),imaginal disc & septate junction,adherens junction | ectopic,septate junction,pleated septate junction,cell autonomous,egg chamber,imaginal disc & epithelial cell & plasma membrane | somatic clone,imaginal disc & epithelial cell & septate junction | somatic clone,epithelial cell,neuroblast,embryonic epidermis,presumptive embryonic/larval nervous system,germline cell,embryonic neuroblast,embryonic/first instar larval cuticle,eye-antennal disc,subsynaptic reticulum | third instar larval stage,puparium,prepupal cuticle,dorsal,maternal effect,postsynaptic membraneBG487,subsynaptic reticulumBG487,subsynaptic reticulumMhc.PW" FBgn0035481 CG12605 - http://flybase.org/reports/FBgn0035481 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "anon-WO0140519.93, CG12605" IPR013087:Zinc finger C2H2-type CG12605 11-Aug-17 DroID_v2017_08 "Drer\hic1l, Drer\mynn, Drer\snai1a, Drer\scrt1a, Drer\zbtb46, Drer\zbtb17, Drer\zbtb14, Drer\zbtb18, Drer\zbtb7c, Drer\zbtb49, Drer\zbtb7a, Drer\scrt2, Drer\hic2, Drer\snai2, Drer\zbtb16b, Drer\snai3, Drer\scrt1b, Drer\zbtb24, Drer\zbtb16a, Drer\bcl6ab, Drer\zbtb8b, Drer\zbtb10, Drer\snai1b" "Scer\MET32, Scer\AZF1" "Cele\ces-1, Cele\snai-1, Cele\Y111B2A.10" "Xtro\znf238.2, Xtro\zbtb49, Xtro\snai1, Xtro\zbtb3, Xtro\zbtb7c, Xtro\hic1, Xtro\zbtb18, Xtro\hic2, Xtro\ikzf2, Xtro\snai2, Xtro\zbtb26, Xtro\gzf1, Xtro\zbtb8b, Xtro\zbtb41" "Mmus\Zbtb49, Mmus\Zfp580, Mmus\Zbtb46, Mmus\Hic2, Mmus\Zbtb24, Mmus\Zbtb14, Mmus\Zbtb42, Mmus\Zbtb7c, Mmus\Scrt2, Mmus\Zbtb16, Mmus\Mynn, Mmus\Zbtb3, Mmus\Zbtb26, Mmus\Zbtb7a, Mmus\Snai2, Mmus\Patz1, Mmus\Zbtb7b, Mmus\Scrt1, Mmus\Zbtb41, Mmus\Snai1, Mmus\Snai3, Mmus\Bcl6b, Mmus\Zbtb18, Mmus\Zbtb8b" "Hsap\SCRT1, Hsap\ZBTB24, Hsap\SCRT2, Hsap\ZBTB14, Hsap\ZBTB3, Hsap\SNAI3, Hsap\ZBTB41, Hsap\SNAI1, Hsap\ZBTB7A, Hsap\ZNF580, Hsap\ZBTB16, Hsap\ZBTB7C, Hsap\ZBTB26, Hsap\MYNN, Hsap\HIC2, Hsap\ZBTB48, Hsap\ZBTB42, Hsap\BCL6B, Hsap\ZBTB8B, Hsap\SNAI2, Hsap\PATZ1, Hsap\ZBTB18, Hsap\ZBTB49" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" DRSC08286 I 0.579470683 1.792496216 0.72158708 -0.337274373 1.139316112 0.733306549 FBgn0002543 robo2 roundabout 2 http://flybase.org/reports/FBgn0002543 "FBgn0024195, FBgn0025977, FBgn0031338, FBgn0031339, FBgn0031340, FBgn0031341" protein_coding_gene receptor activity ; GO:0004872 | traceable author statement protein homodimerization activity ; GO:0042803 | inferred from direct assay "axon guidance ; GO:0007411 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype neuron migration ; GO:0001764 | inferred from mutant phenotype positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype salivary gland boundary specification ; GO:0007432 | inferred from mutant phenotype central complex development ; GO:0048036 | inferred from mutant phenotype regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype outflow tract morphogenesis ; GO:0003151 | inferred from genetic interaction with robo1 synaptic target recognition ; GO:0008039 | inferred from mutant phenotype cardioblast cell fate specification ; GO:0042685 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement gonad development ; GO:0008406 | inferred from mutant phenotype" axon ; GO:0030424 | inferred from direct assay "lea, robo2, Robo2, CG5481, Robo-2, Robo 2, CT17326, dRobo-2, robo-2, D-Robo2, D-robo2, clone 1.75, anon-EST:Liang-1.75, CG5574, CG14348, CG14347, ROBO2, fus4, Robo2 (Lea)" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG5481 11-Aug-17 DroID_v2017_08 "Drer\robo3, Drer\robo1, Drer\igsf9a, Drer\robo2, Drer\robo4, Drer\igsf9b" - "Cele\sax-3, Cele\egl-15" "Xtro\robo4, Xtro\robo3, Xtro\igsf9b, Xtro\robo1" "Mmus\Igsf9b, Mmus\Igdcc3, Mmus\Myom1, Mmus\Robo1, Mmus\Robo2, Mmus\Robo3, Mmus\Robo4" "Hsap\IGDCC3, Hsap\ROBO4, Hsap\MYOM1, Hsap\ROBO1, Hsap\ROBO2, Hsap\ROBO3, Hsap\IGSF9B" " embryonic stage | stage 14 , embryonic stage | stage 13-14 , embryonic stage | stage 13 " " embryonic dorsal trunk && embryonic transverse connective && embryonic dorsal branch && embryonic spiracular branch && embryonic ganglionic branch

, epidermis | dorsal & vicinity of segment boundary

, embryonic dorsal trunk && embryonic transverse connective && embryonic dorsal branch

" "neuroanatomy defective,male,lethal,partially lethal - majority die,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neurophysiology defective,viable,fertile" "gustatory receptor neuron,male,prothoracic leg taste bristle chemosensory neuron,heart primordium,serotonin neuron & ventral nerve cordeg-Mz360,cell body & serotonin neuroneg-Mz360,intersegmental nerve,abdominal lateral pentascolopidial chordotonal organ lch5,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial dendrite,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial dendritic cap cell,ventral nerve cord commissure,antennal commissure,antennal lobe glomerulus,dMP2 neuron,vMP2 neuron,gonad,gonadal sheath proper primordium,commissure,embryonic/larval neuron,ganglionic branch primordium,longitudinal connective,tract,ectopic | embryonic stage,hypostomal sclerite,cephalopharyngeal skeleton,embryonic somatic muscle,lateral process,intermediate longitudinal fascicle,lateral longitudinal fascicle,germline cell,dorsal branch primordium,interface glial cell,fascicle,cardioblast,lch5 neuron,presumptive embryonic/larval central nervous system,ventral nerve cord,motor neuron,ellipsoid body,fan-shaped body,adult mushroom body,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,head,ventral,presumptive embryonic salivary gland,olfactory neuron & antennal lobe | somatic clone,antennal lobe glomerulus DM2,somatic clone,ectopic,embryonic head,serotonin neuron & ventral nerve cord,cell body & serotonin neuron,embryonic pericardial cell,mesothoracic dorsal triscolopidial chordotonal organ dch3,metathoracic dorsal triscolopidial chordotonal organ dch3,giant fiber neuron,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,tergal depressor of trochanter muscle motor neuron & dendriteshakB.lethal.4.1,medial longitudinal fascicle,dorsal branch | third instar larval stage" FBgn0015218 eIF4E1 eukaryotic translation initiation factor 4E1 http://flybase.org/reports/FBgn0015218 "FBgn0002202, FBgn0010921, FBgn0013947, FBgn0028178, FBgn0035984, FBgn0060598, FBgn0060792, FBgn0061015" protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from genetic interaction with SGD:S000005499 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC:3287 inferred from sequence or structural similarity with MGI:MGI:95305 RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay RNA cap binding ; GO:0000339 | inferred from direct assay RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from direct assay eukaryotic initiation factor 4G binding ; GO:0031370 | inferred from physical interaction with eIF4G1 protein binding ; GO:0005515 | inferred from physical interaction with Thor protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VD44 positive regulation of cell growth ; GO:0030307 | traceable author statement salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern male germ-line cyst formation ; GO:0048136 | inferred from mutant phenotype meiotic chromosome condensation ; GO:0010032 | inferred from mutant phenotype translation ; GO:0006412 | inferred from direct assay chromatin organization ; GO:0006325 | inferred from mutant phenotype RNA metabolic process ; GO:0016070 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of cell growth ; GO:0001558 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from genetic interaction with SGD:S000005499 translational initiation ; GO:0006413 | inferred from direct assay spermatocyte division ; GO:0048137 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern translation ; GO:0006412 | inferred from sequence or structural similarity with HGNC:3287 inferred from sequence or structural similarity with MGI:MGI:95305 male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype cap-dependent translational initiation ; GO:0002191 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:3287 inferred from sequence or structural similarity with MGI:MGI:95305 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from physical interaction with eIF4G1 cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay eukaryotic translation initiation factor 4F complex ; GO:0016281 | non-traceable author statement mRNA cap binding complex ; GO:0005845 | inferred from sequence or structural similarity with UniProtKB:P63073 muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay "eIF4E, CBP, eif-4E, eIF-4EII, CG4035, eIF-4e, eIF4e, deIF4E, eIF-4E1,2, CT39426, CT39424, CT13384, D-eIF4E, IF4E, 7238, 0919/12, 0587/11, 0260/09, 0589/11, 1004/13, Eif4e, l(3)07238, l(3)67Af, Eif4E, l(3)S025007, l(3)S026009, l(3)S058711, l(3)S091912, eIF4E-1, eIF4E-2, eif-4e, deIF-4E, eIF-4E, eif4e, EIF4E, eIF4E-1,2, eIF-4E2, eIF-4E1, eIF4E1, eIF 4E, dEif4e, eIF4E-1/2, eIF4EI, elF4E" "IPR001040:Translation Initiation factor eIF- 4e, IPR019770:Eukaryotic translation initiation factor 4E (eIF-4E), conserved site, IPR023398:Translation Initiation factor eIF- 4e-like" CG4035 11-Aug-17 DroID_v2017_08 "Drer\eif4ea, Drer\sesn1, Drer\si:zfos-80g12.1, Drer\sesn2, Drer\eif4eb, Drer\eif4e1c, Drer\eif4e1b" Scer\CDC33 "Cele\ife-5, Cele\ife-2, Cele\ife-3, Cele\ife-1" "Xtro\eif4e1b, Xtro\sesn1, Xtro\sesn3, Xtro\eif4e" "Mmus\Sesn2, Mmus\Sesn3, Mmus\Eif4e1b, Mmus\Sesn1, Mmus\Eif4e" "Hsap\EIF4E1B, Hsap\EIF4E, Hsap\SESN2, Hsap\SESN3, Hsap\SESN1" " embryonic stage , embryonic stage -- adult stage " " embryonic/larval salivary gland

, embryonic/larval somatic muscle

, pole cell

, embryonic/larval digestive system

, posterior midgut proper primordium

, anterior midgut proper primordium

,

ubiquitous " "viable,lethal,recessive,developmental rate defective,reduced,visible,lethal - all die before end of larval stage,some die during larval stage,decreased cell size,increased cell size,meiotic cell cycle defective,dominant,mitotic cell cycle defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,some die during third instar larval stage,wild-type,female sterile,germline clone,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage,neurophysiology defective,neuroanatomy defective,chemical sensitive,male,partially lethal - majority die,female,lethal - all die before end of pupal stage,some die during pupal stage" "wing,intersegmental nerve,wing disc,ommatidium,mitosis & nuclear chromosome,mitotic interphase,ventral furrow,embryonic/first instar larval cuticle,eye,interommatidial bristle,ectopic,neuromuscular junctionMhc.PW,bouton,type I bouton,embryonic/larval neuromuscular junction,dopaminergic neuron,embryonic/larval neuroblast,ganglion mother cell" DRSC11342 IEK -1.504138538 -0.970498401 -6.318141051 -2.31893895 -1.643970291 -1.296136804 FBgn0003334 Scm Sex comb on midleg http://flybase.org/reports/FBgn0003334 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR010507, InterPro:IPR012313 zinc ion binding ; GO:0008270 | non-traceable author statement identical protein binding ; GO:0042802 | inferred from physical interaction with UniProtKB:Q9VHA0 protein binding ; GO:0005515 | inferred from physical interaction with Sfmbt protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P39769 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR004092 gene silencing ; GO:0016458 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from mutant phenotype inferred from genetic interaction with ph-p negative regulation of growth ; GO:0045926 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement inferred by curator from GO:0016458 ventral cord development ; GO:0007419 | inferred from mutant phenotype" PRC1 complex ; GO:0035102 | colocalizes_with inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0016458 nucleus ; GO:0005634 | inferred from direct assay PRC1 complex ; GO:0035102 | traceable author statement "CG9495, scm, SCM, Su(z)302, l(3)85Ef, Scm" "IPR010507:Zinc finger, MYM-type, IPR001660:Sterile alpha motif domain, IPR004092:Mbt repeat, IPR012313:Zinc finger, FCS-type, IPR013761:Sterile alpha motif/pointed domain, IPR021987:SLED domain" CG9495 11-Aug-17 DroID_v2017_08 "Drer\sfmbt2, Drer\scmh1, Drer\scml2, Drer\scml4" - "Cele\W04B5.2, Cele\F49B2.3" "Xtro\scmh1, Xtro\scml4, Xtro\scml2" "Mmus\Scmh1, Mmus\Scml2, Mmus\Sfmbt2, Mmus\Scml4, Mmus\Sfmbt1" "Hsap\SFMBT1, Hsap\SFMBT2, Hsap\SCMH1, Hsap\SCML2, Hsap\SCML4" " adult stage && oogenesis stage , embryonic stage | >12 hr , embryonic stage--pupal stage " " ovary

, embryonic central nervous system

" "neuroanatomy defective,lethal,recessive,some die during pharate adult stage,heat sensitive,visible,dominant,homeotic,decreased cell number,somatic clone,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage,non-suppressor of variegation,non-enhancer of variegation,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,male,female" "dendritic arborizing neuron,axon,sex comb,wing,pigment cell,embryo,egg chamber,interfollicle cell,ectopic,mesothoracic leg,embryonic/first instar larval cuticle,adult abdominal segment 4,adult abdominal segment 5,abdominal tergite 4,male,adult abdominal segment 6,adult abdominal segment 7,abdominal tergite 6,embryonic segment,neuroblast,somatic clone,larval abdominal segment 1,larval abdominal segment 2,larval abdominal segment 3,larval abdominal segment 4,larval abdominal segment 5,larval abdominal segment 6,larval abdominal segment 7,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,larval abdominal segment 8,germline clone,haltere,leg,antenna,female,mesothoracic tergum" DRSC16853 K -0.053243445 -0.288316958 -0.291297165 -0.169238593 1.546783495 0.630053977 FBgn0004110 tin tinman http://flybase.org/reports/FBgn0004110 "FBgn0002850, FBgn0002944" protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay" "germ cell migration ; GO:0008354 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from expression pattern cardiocyte differentiation ; GO:0035051 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay mesoderm development ; GO:0007498 | inferred from expression pattern cardioblast cell fate determination ; GO:0007510 | traceable author statement pole cell migration ; GO:0007280 | traceable author statement embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype mesodermal cell fate specification ; GO:0007501 | traceable author statement lymph gland development ; GO:0048542 | inferred from mutant phenotype cardiocyte differentiation ; GO:0035051 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement mesoderm development ; GO:0007498 | traceable author statement cell fate specification ; GO:0001708 | non-traceable author statement gonad development ; GO:0008406 | traceable author statement pericardial nephrocyte differentiation ; GO:0061320 | inferred from mutant phenotype cardioblast differentiation ; GO:0010002 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement germ cell migration ; GO:0008354 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype determination of digestive tract left/right asymmetry ; GO:0071907 | inferred from mutant phenotype neuroendocrine cell differentiation ; GO:0061101 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype metamorphosis ; GO:0007552 | traceable author statement cardiac muscle cell differentiation ; GO:0055007 | inferred from mutant phenotype embryonic anterior midgut (ectodermal) morphogenesis ; GO:0048615 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Tin, tin/NK4, NK-4, NK4, HOX, DROHOXHK4, DmNK-4, NK4/msh-2, NK-4/msh-2, msh-2, msh2, CG7895, tin, DROHOXNK4, TIN, NKX2.5" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG7895 11-Aug-17 DroID_v2017_08 "Drer\hoxd4a, Drer\nkx2.7, Drer\hoxd13a, Drer\nkx2.9, Drer\nkx2.2a, Drer\nkx3-1, Drer\nkx2.1, Drer\nkx3.2, Drer\nkx2.3, Drer\nkx2.4b, Drer\hoxc13a, Drer\nkx2.5, Drer\hoxa13a, Drer\hoxb13a, Drer\nkx2.2b, Drer\nkx2.4a, Drer\nkx3.3" - "Cele\ceh-28, Cele\ttx-1, Cele\ceh-13, Cele\ceh-62, Cele\ceh-24, Cele\ceh-16" "Xtro\nkx2-6, Xtro\nkx2-2, Xtro\nkx2-8, Xtro\nkx3-1, Xtro\nkx3-2, Xtro\nkx2-5, Xtro\nkx2-3, Xtro\nkx3-3, Xtro\nkx2-1" "Mmus\Hoxd13, Mmus\Nkx2-1, Mmus\Nkx2-2, Mmus\Hoxc13, Mmus\Nkx2-6, Mmus\Nkx2-3, Mmus\Nkx2-4, Mmus\Nkx3-2, Mmus\Nkx3-1, Mmus\Nkx2-9, Mmus\Nkx2-5" "Hsap\NKX2-1, Hsap\NKX2-5, Hsap\NKX2-4, Hsap\NKX2-2, Hsap\HOXD13, Hsap\NKX3-1, Hsap\NKX2-6, Hsap\NKX2-8, Hsap\NKX3-2, Hsap\HOXC13, Hsap\NKX2-3" " embryonic stage | stage 11 , embryonic stage | stage >11 , embryonic stage | late , embryonic stage , embryonic stage | stage >=11 " " cardiogenic mesoderm

, cardioblast

, embryonic/larval dorsal vessel

, mesoderm | dorsal

, mesoderm

, visceral mesoderm

, visceral mesoderm | restricted

" " embryonic stage | stage 11 , embryonic stage | stage 11-12 , embryonic stage | stage 15-16 , embryonic stage | stage 10 , embryonic stage | stage 8-9 " " cardiogenic mesoderm

, pericardial cell

, mesoderm | dorsal

, trunk mesoderm

, visceral mesoderm

, cardioblast

" "wild-type,neuroanatomy defective,decreased cell death,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,short lived,lethal,flight defective,viable,visible" "midgut muscle,cardioblast,embryonic garland cell,lymph gland primordium,segment border muscle,embryonic/larval dorsal vessel,embryonic/larval visceral muscle,germline cell,gonadal sheath proper primordium,corpus cardiacum primordium,heart primordium,lateral intersegmental nerve root glial cell,bipolar dendrite neuron,dorsal neurohemal organ,transverse nerve & dorsal prothoracic disc,transverse nerve & dorsal mesothoracic disc,transverse nerve & dorsal metathoracic disc,abdominal transverse nerve,embryonic/larval heart & mesoderm,visceral mesoderm,somatic mesoderm,dorsal,embryonic/larval dorsal trunk,midgut constriction 1,midgut constriction 2,midgut constriction 3,embryonic/larval heart,somatic muscle,longitudinal visceral muscle primordium,endoderm,foregut visceral muscle primordium,embryonic brain,embryonic/larval lymph gland,myofibril & larval dorsal vessel, with tinABD,myofibril & larval heart, with tinABD,adult dorsal vessel,myofibril & adult dorsal vessel, with tinABD,adult heart,embryonic/larval aorta,ventral nerve cord,muscle founder cell,embryonic/larval pericardial cell,presumptive embryonic salivary gland,circular visceral muscle primordium,gonad & parasegment 10,gonad & parasegment 11,gonad & parasegment 12,embryonic/larval fat body & parasegment 3,embryonic/larval fat body & parasegment 13,abdominal 2 dorsal transverse muscle 1,abdominal 3 dorsal transverse muscle 1,abdominal 4 dorsal transverse muscle 1,abdominal 5 dorsal transverse muscle 1,abdominal 6 dorsal transverse muscle 1,abdominal 7 dorsal transverse muscle 1,cardiogenic mesoderm,embryonic pericardial cell,anterior embryonic/larval midgut,myofibril & larval dorsal vessel, with tinEC40/tin346,myofibril & larval heart, with tinEC40/tin346,myofibril & adult dorsal vessel, with tinEC40/tin346,pericardial cell,mesothoracic tergum" FBgn0004611 Plc21C Phospholipase C at 21C http://flybase.org/reports/FBgn0004611 - protein_coding_gene "phosphatidylinositol phospholipase C activity ; GO:0004435 | inferred from electronic annotation with InterPro:IPR001711, InterPro:IPR016280, InterPro:IPR028407 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR016280 signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR028407" "lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR001711, InterPro:IPR017946 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001192, InterPro:IPR001711 neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with FLYBASE:GluRIinferred by curator; FB:FBgn0046113 flight behavior ; GO:0007629 | inferred from genetic interaction with Gαq, Itp-r83A regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from genetic interaction with FLYBASE:GluRIinferred by curator; FB:FBgn0046113" - "PLC-21C, PLC, CG4574, PLC[[Beta]], plc21, plc-21, Plc21C, PLC21C, PLC-21, plc21c, Plcbeta21C, PLC21c, plc21C, plcbeta21c, Plc21" "IPR000008:C2 domain, IPR000909:Phosphatidylinositol-specific phospholipase C, X domain, IPR001192:Phosphoinositide phospholipase C family, IPR001711:Phospholipase C, phosphatidylinositol-specific, Y domain, IPR011992:EF-hand domain pair, IPR011993:PH domain-like, IPR015359:Phosphoinositide-specific phospholipase C, EF-hand-like domain, IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain, IPR016280:Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta, IPR028407:Phospholipase C, Plc21C" CG4574 11-Aug-17 DroID_v2017_08 "Drer\plcb2, Drer\plcb3, Drer\plch2, Drer\plce1, Drer\plcd3a, Drer\LOC100334276, Drer\plcb4, Drer\plcd3b, Drer\plcd4a, Drer\plch1, Drer\plcd1b, Drer\plcd4b, Drer\si:ch211-210g13.5, Drer\plch2b" Scer\PLC1 "Cele\egl-8, Cele\plc-2" "Xtro\plcd3, Xtro\plch1, Xtro\plcd1, Xtro\plcb3, Xtro\plch2, Xtro\plcd4, Xtro\plcb1, Xtro\plcb4, Xtro\plcl2" "Mmus\Plcb4, Mmus\Plcd3, Mmus\Plce1, Mmus\Plcd4, Mmus\Plcl1, Mmus\Plcd1, Mmus\Plcl2, Mmus\Plcz1, Mmus\Plch1, Mmus\Plch2, Mmus\Plcb3, Mmus\Plcb1, Mmus\Plcb2" "Hsap\PLCE1, Hsap\PLCZ1, Hsap\PLCB3, Hsap\PLCB1, Hsap\PLCH2, Hsap\PLCL2, Hsap\PLCH1, Hsap\PLCL1, Hsap\PLCD3, Hsap\PLCD4, Hsap\PLCB2, Hsap\PLCD1, Hsap\PLCB4" " larval stage , adult stage , embryonic stage -- adult stage , adult stage | female " " larval brain

, head

, oocyte

, thoracico-abdominal ganglion

, adult brain

, optic lobe

" "viable,fertile,neurophysiology defective,dominant,circadian rhythm defective" adult olfactory receptor neuron Or59b FBgn0038923 mRpL35 mitochondrial ribosomal protein L35 http://flybase.org/reports/FBgn0038923 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9NZE8 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR021137 mitochondrial translation ; GO:0032543 | traceable author statement epithelium development ; GO:0060429 | inferred from mutant phenotype mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9NZE8 "MRP-L35, CG13410, BcDNA:RE35766, mRpL35" "IPR019338:Ribosomal protein L35, mitochondrial, IPR021137:Ribosomal protein L35" CG13410 11-Aug-17 DroID_v2017_08 Drer\mrpl35 - Cele\mrpl-35 Xtro\mrpl35 Mmus\Mrpl35 Hsap\MRPL35 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,epithelium,female germline cyst" FBgn0003041 pbl pebble http://flybase.org/reports/FBgn0003041 "FBgn0010935, FBgn0046405, FBgn0046407" protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR026817 Rho GTPase binding ; GO:0017048 | inferred from physical interaction with Rho1 semaphorin receptor binding ; GO:0030215 | inferred from physical interaction with Sema1a Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with HGNC:3155 Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | traceable author statement Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from direct assay Rac guanyl-nucleotide exchange factor activity ; GO:0030676 | inferred from direct assay phosphatidylinositol phosphate binding ; GO:1901981 | inferred from direct assay positive regulation of neuron differentiation ; GO:0045666 | inferred from electronic annotation with InterPro:IPR026817 regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | traceable author statement negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:3155 regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with LIMK1 negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype mitotic actomyosin contractile ring assembly ; GO:1903475 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from genetic interaction with Rac1 inferred from genetic interaction with Rac2 meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype mesodermal cell migration ; GO:0008078 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype defasciculation of motor neuron axon ; GO:0007415 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement cell adhesion ; GO:0007155 | inferred from mutant phenotype cleavage furrow ; GO:0032154 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement cell cortex ; GO:0005938 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "pbl, pebble, CG8114, PBL, l(3)09645, 0542/03, 0293/09, 0083/20, anon-WO0172774.25, anon-WO0172774.22, Pbl, ECT2, GEF, Ect-2, Pbl/Ect2" "IPR000219:Dbl homology (DH) domain, IPR001357:BRCT domain, IPR011993:PH domain-like, IPR026817:Guanine nucleotide exchange factor Ect2" CG8114 11-Aug-17 DroID_v2017_08 "Drer\ect2l, Drer\ect2, Drer\topbp1" - "Cele\mus-101, Cele\ect-2" "Xtro\ect2, Xtro\topbp1" "Mmus\Ect2l, Mmus\Topbp1, Mmus\Ect2" "Hsap\ECT2L, Hsap\ECT2, Hsap\ARHGEF10L" embryonic stage -- adult stage "lethal - all die during embryonic stage,wild-type,neuroanatomy defective,visible,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,germline clone,cytokinesis defective,mitotic cell cycle defective,cell migration defective,meiotic cell cycle defective,male,male sterile,majority die during embryonic stage,temperature conditional,partially lethal - majority die" "spindle,embryonic/larval cuticle,anterior fascicle & synapse | supernumerary,eye,scutellar bristle,trichogen cell,ectopic,tormogen cell,thecogen cell,temperature conditional,interommatidial bristle,ommatidium,wing vein,presumptive embryonic/larval peripheral nervous system,neuron,intersegmental nerve,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,epithelium,egg chamber,embryonic/larval neuroblast,somatic clone,embryonic/larval brain,embryonic/larval hindgut,mesoderm,Malpighian tubule,embryonic/larval sense organ,precursor,trunk mesoderm,actomyosin contractile ring,centrosome,spermatid & nucleus | supernumerarypbl-NR),Nebenkern,spindle & meiotic cell cycle | malepbl-NR),contractile ring & meiotic cell cycle | malepbl-NR),spermatid & nucleus | supernumerary,spindle & meiotic cell cycle | male,contractile ring & meiotic cell cycle | male,visceral mesoderm,visceral mesoderm derivative,somatic muscle,somatic mesoderm,neuroblast NB6-4 of thorax,neuroblast NB6-4 of abdomen,ventral,abdominal ventral denticle belt,embryo,mitotic telophase,mitotic telophase & spindle,pigment cell,rhabdomereGMR.PF,wing,posterior compartment,wing hair,supernumerary,actomyosin contractile ringprd.RG1,posterior,wing | posterior & wing hairen-e16E,dorsal mesothoracic disc & cell & third instar larvaen-e16E,G2 phase of mitotic cell cycle & dorsal mesothoracic disc & third instar larvaen-e16E,mesoderm | embryonic stage 8,eye | adult stage,S2 cell-line & cell,S2 cell-line & spindle microtubule,ganglion mother cell,mesothoracic tergum" FBgn0002932 neur neuralized http://flybase.org/reports/FBgn0002932 "FBgn0011395, FBgn0011419, FBgn0011420, FBgn0011422, FBgn0011470, FBgn0046269" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with E(spl)m4-BFM, E(spl)mα-BFM protein binding ; GO:0005515 | inferred from physical interaction with Brd inferred from physical interaction with E(spl)m4-BFM inferred from physical interaction with E(spl)m6-BFM inferred from physical interaction with E(spl)mα-BFM inferred from physical interaction with Tom inferred from physical interaction with Ocho inferred from physical interaction with BobC inferred from physical interaction with BobB inferred from physical interaction with BobA phosphatidylinositol phosphate binding ; GO:1901981 | inferred from direct assay" peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | traceable author statement regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement brain morphogenesis ; GO:0048854 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from direct assay locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype protein homooligomerization ; GO:0051260 | inferred from physical interaction with neur nervous system development ; GO:0007399 | non-traceable author statement regulation of compound eye photoreceptor development ; GO:0045314 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement regulation of photoreceptor cell differentiation ; GO:0046532 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement mesoderm development ; GO:0007498 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | traceable author statement negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay endosome ; GO:0005768 | colocalizes_with inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "neuralized, Neur, neu, CG11988, 1315/05, 1293/09, 0971/15, 0328/12, BEST:LD21494, l(3)neo37, l(3)j9C8, l(3)j9B9, l(3)j9B8, l(3)j6B12, neur" "IPR001841:Zinc finger, RING-type, IPR006573:Neuralized homology repeat (NHR) domain" CG11988 11-Aug-17 DroID_v2017_08 "Drer\neurl1ab, Drer\neurl4, Drer\neurl1b, Drer\neurl1aa" - Cele\F10D7.5 "Xtro\neurl1b, Xtro\neurl1, Xtro\neurl4" "Mmus\Neurl1b, Mmus\Neurl4, Mmus\Neurl3, Mmus\Neurl1a" "Hsap\NEURL1, Hsap\NEURL1B, Hsap\NEURL3, Hsap\NEURL4" " embryonic stage | early , embryonic stage | 3-9 hr , embryonic stage | stage 5 , wandering third instar larval stage , embryonic stage -- adult stage , larval stage | third instar stage 2 , embryonic stage | stage 9 , embryonic stage , embryonic stage | 0-12 hr , embryonic stage | stage 10 , adult stage | female " " mesectoderm

, neuroblast

, epidermoblast

, mesoderm | presumptive

, mesoderm

, ectoderm

, larval inner optic anlage

, eye-antennal disc | restricted

, larval outer optic anlage

, ventral neurogenic region

, sensory mother cell &&of dorsal mesothoracic disc

, adult neuroblast

" larval stage | third instar eye disc

"viable,smell perception defective,visible,behavior defective,male,neuroanatomy defective,lethal,recessive,neurogenic phenotype,somatic clone,locomotor behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,partially lethal - majority die,memory defective,lethal - all die before end of pupal stage,some die during pupal stage,planar polarity defective,temperature conditional" "sternopleural bristle,female,male,microchaeta & sternite | male,mushroom body alpha-lobe,ellipsoid body,wing margin,embryonic/larval nervous system,apterous-expressing neuron of the lateral cluster of the thorax,crystal cell,female germline stem cell,germline clone,macrochaeta & mesothoracic tergum | supernumerary | somatic clone,microchaeta,somatic clone,supernumerary,macrochaeta,chemosensory ventral triple row bristle,mechanosensory ventral triple row bristle,cell autonomous,ectopic,eye,ommatidium,interommatidial bristle,eye photoreceptor cell,wing margin bristle,wing vein,sensory mother cell,rhabdomere,microchaeta & sternite | female,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,wing vein L4,wing vein L5,wing vein L2,wing vein L3,adult thoracic sensillum,neuron & peripheral nervous system,neuroblast,embryonic epidermis,ectoderm,external sensory organ precursor cell,sensory neuron & peripheral nervous system,dorsal mesothoracic disc & sensory mother cell | dorsal/ventral compartment boundary,exit glial cell,peripheral glial cell,embryonic/larval glial cell,embryonic/larval somatic muscle,neuron & eye | supernumerary | somatic clone,germline stem cell,nervous system,presumptive embryonic/larval nervous system,socket,triple row,embryonic myoblast,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,trichogen cell,tormogen cell,eo neuron,thecogen cell,head bristle,thorax & chaeta | somatic clone,external sensory organ precursor cell I,macrochaeta & mesothoracic tergum | somatic clone,pigment cell,cuticle & macrochaeta | somatic clone,embryonic/larval dorsal vessel,precursor,eye photoreceptor cell & ommatidium | ectopic | somatic clone,lens,rhabdomere | cell autonomous | somatic clone,adult midgut,enterocyte,sensillum campaniformium of dorsal radius,distal,sensillum campaniformium,photoreceptor cell,eye disc,wing,dorsocentral bristle,adult epidermis,cone cell,mesothoracic tergum,macrochaeta & head-537.4,chaeta,dorsal cluster neuron,medulla" FBgn0010379 Akt1 Akt1 http://flybase.org/reports/FBgn0010379 "FBgn0010837, FBgn0013324, FBgn0017365" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017892 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay phosphatidylinositol binding ; GO:0035091 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VJ07 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity" "positive regulation of cell growth ; GO:0030307 | traceable author statement <> positive regulation of cell proliferation ; GO:0008284 | NOT inferred from mutant phenotype <> regulation of dendrite development ; GO:0050773 |... mutant phenotype <> regulation of hemocyte proliferation ; GO:0035206 |... mutant phenotype <> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <> protein phosphorylation ; GO:0006468 |... direct assay <> cholesterol homeostasis ; GO:0042632 |... mutant phenotype <> regulation of multicellular organism growth ; GO:0040014 |... mutant phenotype <> positive regulation of cell size ; GO:0045793 | traceable author statement <> oogenesis ; GO:0048477 |... mutant phenotype <> positive regulation of cell growth ; GO:0030307 |... mutant phenotype <> positive regulation of cell size ; GO:0045793 |... mutant phenotype <> regulation of multicellular organism growth ; GO:0040014 | non-traceable author statement <> somatic muscle development ; GO:0007525 |... mutant phenotype <> insulin receptor signaling pathway ; GO:0008286 |... genetic interaction with UniProtKB:P91634 <> dendrite regeneration ; GO:0031104 |... mutant phenotype <> regulation of organ growth ; GO:0046620 | non-traceable author statement <> positive regulation of organ growth ; GO:0046622 | traceable author statement <> open tracheal system development ; GO:0007424 | traceable author statement <> regulation of cell shape ; GO:0008360 |... mutant phenotype <> negative regulation of apoptotic process ; GO:0043066 |... mutant phenotype <> regulation of glucose metabolic process ; GO:0010906 |... mutant phenotype <> insulin receptor signaling pathway ; GO:0008286 |... direct assay <> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 |... genetic interaction with Pi3K21B <> epithelial cell migration, open tracheal system ; GO:0007427 |... mutant phenotype <> regulation of cell size ; GO:0008361 | non-traceable author statement <> intracellular signal transduction ; GO:0035556 |... genetic interaction with UniProtKB:P91634 <> myoblast fusion ; GO:0007520 |... mutant phenotype <> response to oxidative stress ; GO:0006979 |... mutant phenotype <> negative regulation of peptide hormone secretion ; GO:0090278 |... mutant phenotype <> open tracheal system development ; GO:0007424 |... mutant phenotype <> insulin receptor signaling pathway ; GO:0008286 | non-traceable author statement <> positive regulation of cell size ; GO:0045793 | non-traceable author statement <> long term synaptic depression ; GO:0060292 |... mutant phenotype <> negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 |... mutant phenotype <> lipid storage ; GO:0019915 |... genetic interaction with Pten <> insulin receptor signaling pathway ; GO:0008286 | traceable author statement <> peptidyl-serine phosphorylation ; GO:0018105 |... biological aspect of ancestor with PANTHER:PTN000683254 <> lipid metabolic process ; GO:0006629 |... mutant phenotype <> multicellular organism growth ; GO:0035264 |... mutant phenotype <> protein phosphorylation ; GO:0006468 | non-traceable author statement <> positive regulation of cell growth ; GO:0030307 | non-traceable author statement <> negative regulation of neuron death ; GO:1901215 |... genetic interaction with grim <> circadian rhythm ; GO:0007623 |... mutant phenotype <> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <> positive regulation of axon regeneration ; GO:0048680 |... mutant phenotype <> positive regulation of organ growth ; GO:0046622 | non-traceable author statement <> positive regulation of organ growth ; GO:0046622 |... mutant phenotype" plasma membrane ; GO:0005886 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "dAkt1, AKT, Akt, RAC, PKB, dAKT/dPKB, dAkt, PKB/AKT, PKB/Akt, PKB/dAKT, dPKB, Dakt1, Akt/PKB, DAKT1/PKB, dAkt/PKB, Dakt, D-Akt, AKT/PKB, akt, l(3)89Bq, CG4006, DAkt1, l(3)04226, DRAC-PK66; DRAC-PK85, DAKT1, dakt1, DPKB, DRAC-PK, RacPK, Akt1, AKT1, p-Akt, dakt, dAKT1, DAkt, pAkt, P-AKT, akt1, dAKT, Dpkb, Akt1|PKB" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR001849:Pleckstrin homology domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011993:PH domain-like, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal" CG4006 11-Aug-17 DroID_v2017_08 "Drer\rps6kb1b, Drer\stk32a, Drer\sgk2b, Drer\rps6ka5, Drer\akt2l, Drer\rps6ka1, Drer\akt3b, Drer\rps6ka3b, Drer\LOC100331306, Drer\rps6kal, Drer\rps6ka2, Drer\sgk3, Drer\rps6ka4, Drer\rps6ka3a, Drer\akt2, Drer\rps6kb1a, Drer\akt3a, Drer\sgk2a, Drer\akt1, Drer\si:ch211-195b13.1, Drer\sgk1" "Scer\YPK1, Scer\SCH9, Scer\YPK3, Scer\YPK2" "Cele\rsks-1, Cele\akt-2, Cele\C56G2.5, Cele\snt-5, Cele\rskn-1, Cele\rskn-2, Cele\Y37D8A.25, Cele\T24D5.4, Cele\sgk-1, Cele\akt-1" "Xtro\rps6ka4, Xtro\sgk2, Xtro\rps6ka3, Xtro\rps6ka6, Xtro\rps6ka2, Xtro\akt1, Xtro\akt2, Xtro\stk32a, Xtro\rps6ka1, Xtro\rps6kb1, Xtro\sgk1" "Mmus\Rps6kb2, Mmus\Rps6ka4, Mmus\Sgk1, Mmus\Rps6kb1, Mmus\Rps6ka1, Mmus\Stk32c, Mmus\Rps6ka6, Mmus\Sgk2, Mmus\Rps6ka3, Mmus\Akt1, Mmus\Rps6ka2, Mmus\Stk32a, Mmus\Sgk3, Mmus\Akt3, Mmus\Rps6ka5, Mmus\Stk32b, Mmus\Akt2" "Hsap\AKT3, Hsap\STK32A, Hsap\RPS6KA5, Hsap\RPS6KA1, Hsap\RPS6KB2, Hsap\RPS6KA6, Hsap\C8orf44-SGK3, Hsap\AKT2, Hsap\RPS6KA2, Hsap\RPS6KA3, Hsap\FAM109A, Hsap\RPS6KB1, Hsap\AKT1, Hsap\SGK3, Hsap\SGK2, Hsap\SGK1, Hsap\STK32B, Hsap\RPS6KA4, Hsap\STK32C" " pupal stage , embryonic stage , adult stage && oogenesis stage , embryonic stage | early , embryonic stage -- adult stage , adult stage | female " "

ubiquitous , nurse cell

" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "chemical resistant,decreased cell death,oxidative stress response defective,circadian rhythm defective,partially lethal - majority die,recessive,small body,decreased cell size,viable,lethal,polyphasic,maternal effect,neurophysiology defective,female sterile,neuroanatomy defective,body size defective,wild-type,visible,somatic clone,lethal - all die before end of embryonic stage,increased cell death,germline clone,cell death defective,cell size defective,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,increased cell size,chemical sensitive,hyperplasia,size defective,planar polarity defective,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell number,short lived,heat sensitive,long lived,RU486 conditional" "embryonic/larval salivary gland,embryonic/first instar larval cuticle,maternal effect,synapse,embryonic/larval neuromuscular junction,neuromuscular junction | third instar larval stage,neuromuscular junction | third instar larval stage, with Akt11,eye,ommatidium,dendrite | larval stage | somatic clone,rhabdomere,somatic clone,germline clone,head capsule,tracheal branch primordium,embryo,wing hair,wing,wing vein,ectopic,neuromuscular junction | third instar larval stage, with Akt1hs.PS,synapse | supernumeraryD42,dendrite | larval stageppk.PG,wing blade,posterior,wing disc,somatic clone | third instar larval stage,embryonic/larval fat body,fat body,interommatidial bristle,wing margin bristle,1st posterior cell,posterior compartment,adult gut,heat sensitive,RU486 conditional,segment border muscle,embryonic/larval somatic muscle,embryonic myoblast" DRSC14108 IK 1.086317136 2.731984412 0.013081322 -0.071213965 0.141132401 1.622026335 FBgn0020496 CtBP C-terminal Binding Protein http://flybase.org/reports/FBgn0020496 "FBgn0002353, FBgn0010799, FBgn0024810, FBgn0047318" protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR006139 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140 protein homodimerization activity ; GO:0042803 | inferred from direct assay transcription corepressor activity ; GO:0003714 | traceable author statement repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with kni transcription corepressor activity ; GO:0003714 | inferred from mutant phenotype transcription corepressor activity ; GO:0003714 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with h repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with sna transcription coactivator activity ; GO:0003713 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Kr" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype ATP-dependent chromatin remodeling ; GO:0043044 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement wing disc development ; GO:0035220 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from genetic interaction with arm inferred from genetic interaction with wg negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype" polytene chromosome ; GO:0005700 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay ISWI-type complex ; GO:0031010 | inferred from direct assay "CtBP, dCtBP, ctbp, RE61183, RE01030, EP(3)3528, 256/16, 0256/16, G9, l(3)G9, l(3)87De, l(3)03464, l(3)03463, CG7583, BcDNA:GH07572, CTBP, Dm-CtBP, l(3)87DE" "IPR006139:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040:NAD(P)-binding domain, IPR029753:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site" CG7583 11-Aug-17 DroID_v2017_08 "Drer\ctbp2l, Drer\zgc:136929, Drer\phgdh, Drer\ctbp2a, Drer\ctbp1" "Scer\YGL185C, Scer\SER33, Scer\SER3, Scer\GOR1, Scer\YPL113C" "Cele\ctbp-1, Cele\C31C9.2" "Xtro\ctbp1, Xtro\ctbp2, Xtro\ctbp2" "Mmus\Ctbp2, Mmus\Ctbp1, Mmus\Phgdh" "Hsap\CTBP2, Hsap\CTBP1, Hsap\PHGDH" " embryonic stage -- adult stage , embryonic stage , oogenesis stage | stage >S10 , adult stage | female , oogenesis stage " " oocyte

, nurse cell

, germarium

" "visible,dominant,lethal,lethal - all die before end of pupal stage,some die during pupal stage,cell polarity defective,viable,fertile,recessive,polyphasic,maternal effect,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,cell autonomous,somatic clone,female sterile" "adult thoracic sensillum,scutellar bristle,dorsocentral bristle,posterior dorsocentral bristle,anterior dorsocentral bristle,mesothoracic tergum,notal microchaeta,supernumerary,embryonic/first instar larval cuticle,maternal effect,ventral,segment,crystal cell,macrochaeta,ectopic,scutum & macrochaeta | maternal effect,scutellum & macrochaeta | maternal effect,denticle belt,germline clone,posterior scutellar bristle,anterior scutellar bristle,posterior postalar bristle,anterior postalar bristle,posterior supraalar bristle,external sensory organ precursor cell,wing margin,adult thorax,scutellum,wing,interommatidial bristle,wing vein,socket,posterior scutellar bristle | adult stage,anterior scutellar bristle | adult stage,posterior dorsocentral bristle | adult stage,anterior dorsocentral bristle | adult stage,posterior postalar bristle | adult stage,anterior postalar bristle | adult stage,posterior supraalar bristle | adult stage,anterior supraalar bristle | adult stage,presutural bristle | adult stage,posterior notopleural bristle | adult stage,notal microchaeta | adult stage,scutellum | adult stage,mesothoracic tergum | adult stage,cyst progenitor cell,somatic clone,anterior supraalar bristle,posterior notopleural bristle,anterior notopleural bristle,cell autonomous,trichogen cell" DRSC16617 EK 0.766601186 -1.250538266 -0.328054519 -2.087191614 1.576850554 -0.99892624 FBgn0022027 Vps25 Vacuolar protein sorting 25 http://flybase.org/reports/FBgn0022027 FBgn0033314 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from biological aspect of ancestor with PANTHER:PTN000322234 structural molecule activity ; GO:0005198 | inferred from biological aspect of ancestor with PANTHER:PTN000322234 structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity with SGD:S000003863 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043328 | inferred from biological aspect of ancestor with PANTHER:PTN000322234 regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype ubiquitin-dependent endocytosis ; GO:0070086 | inferred from mutant phenotype negative regulation of epithelial cell proliferation ; GO:0050680 | inferred from mutant phenotype maintenance of epithelial cell apical/basal polarity ; GO:0045199 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from expression pattern bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype epithelial structure maintenance ; GO:0010669 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from mutant phenotype endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from mutant phenotype imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype cell differentiation ; GO:0030154 | inferred from mutant phenotype ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype ESCRT II complex ; GO:0000814 | inferred from biological aspect of ancestor with PANTHER:PTN000322234 ESCRT II complex ; GO:0000814 | inferred from sequence or structural similarity with SGD:S000003863 "vps25, l(2)44Db, l(2)k08904, CG14750, Vps25, dVps25, VPS25, ESCRT-II, ESCRT-I" "IPR014041:ESCRT-II complex, Vps25 subunit, N-terminal winged helix, IPR008570:ESCRT-II complex, vps25 subunit, IPR011991:Winged helix-turn-helix DNA-binding domain" CG14750 11-Aug-17 DroID_v2017_08 Drer\vps25 Scer\VPS25 Cele\vps-25 Xtro\vps25 Mmus\Vps25 Hsap\VPS25 "lethal,recessive,female sterile,germline clone,hyperplasia,somatic clone,increased cell death,cell autonomous,lethal - all die before end of larval stage,some die during larval stage,endocytosis defective,large body,developmental rate defective,cell non-autonomous,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell number,cell growth defective,lethal - all die before end of pupal stage,some die during pupal stage" "egg,germline clone,eye,somatic clone,wing,leg,eye disc,wing disc,follicle cell,cell autonomous,cell non-autonomous,ommatidial precursor cluster,endosome & imaginal disc epithelial cell | somatic clone | cell autonomous | third instar larval stage,egg chamber,plasma membrane | somatic clone,epithelium,interfollicle cell,female germline cyst,embryonic/larval digestive system,endosome | somatic clone,eye-antennal disc,adult head,early endosome | somatic clone,embryonic/larval brain,male genitalia" FBgn0063410 l(3)3450-M lethal (3) 3450-M http://flybase.org/reports/FBgn0063410 gene - - - l(3)3450-M - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0024234 gbb glass bottom boat http://flybase.org/reports/FBgn0024234 FBgn0004788 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR001111, InterPro:IPR001839, InterPro:IPR017948 cytokine activity ; GO:0005125 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 transforming growth factor beta receptor binding ; GO:0005160 | inferred from sequence or structural similarity with HGNC:1072 inferred from sequence or structural similarity with MGI:MGI:88182 transforming growth factor beta receptor binding ; GO:0005160 | inferred from biological aspect of ancestor with PANTHER:PTN000218063" ventral cord development ; GO:0007419 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from direct assay positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype positive regulation of muscle organ development ; GO:0048636 | inferred from genetic interaction with cv neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype BMP signaling pathway ; GO:0030509 | inferred from biological aspect of ancestor with PANTHER:PTN000218210 synaptic vesicle cycle ; GO:0099504 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype SMAD protein signal transduction ; GO:0060395 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype positive regulation of pathway-restricted SMAD protein phosphorylation ; GO:0010862 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype regulation of MAPK cascade ; GO:0043408 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 extracellular region ; GO:0005576 | inferred from direct assay dense core granule ; GO:0031045 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay type III terminal bouton ; GO:0097467 | inferred from direct assay extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 extracellular region ; GO:0005576 | inferred from sequence or structural similarity "gbb, Gbb, gbb-60A, Dm-GBB, TGF-b, tgfb-60A, 60A, gcn, l(2)60A-J, Gbb-60A, TGFbeta-60A, Tgfbeta-60A, Tgfb-60, SixtyA, vgr/60A, CG5562, GBB, BMP" "IPR001111:TGF-beta, propeptide, IPR001839:Transforming growth factor-beta, C-terminal, IPR015615:Transforming growth factor-beta-related, IPR017948:Transforming growth factor beta, conserved site, IPR029034:Cystine-knot cytokine" CG5562 11-Aug-17 DroID_v2017_08 "Drer\mstnb, Drer\inha, Drer\tgfb2l, Drer\tgfb2, Drer\gdf9, Drer\lft2, Drer\gdf10a, Drer\tgfb1b, Drer\bmp4, Drer\bmp7b, Drer\tgfb3, Drer\admp, Drer\bmp3, Drer\amh, Drer\lft1, Drer\ndr1, Drer\bmp8a, Drer\LOC100329520, Drer\gdf5, Drer\bmp2b, Drer\gdf3, Drer\bmp7a, Drer\bmp5, Drer\inhbab, Drer\inhbb, Drer\bmp10, Drer\tgfb1a, Drer\bmp15, Drer\inhbaa, Drer\spaw, Drer\bmp6, Drer\gdf2, Drer\bmp10l, Drer\ndr2, Drer\gdf6a, Drer\bmp2a, Drer\gdf11, Drer\gdf6b, Drer\mstna, Drer\gdf7, Drer\gdf10b" - "Cele\daf-7, Cele\unc-129, Cele\tig-2, Cele\dbl-1" "Xtro\tgfb2, Xtro\bmp7.2, Xtro\nodal, Xtro\bmp4, Xtro\gdf9, Xtro\tgfb1, Xtro\gdf7, Xtro\bmp7.1, Xtro\bmp2, Xtro\gdf10, Xtro\gdf2, Xtro\gdf3, Xtro\gdf1, Xtro\inhbc.1, Xtro\admp, Xtro\nodal6, Xtro\bmp3, Xtro\lefty, Xtro\bmp15, Xtro\gdf11.1, Xtro\gdf5, Xtro\bmp5, Xtro\nodal5, Xtro\bmp8, Xtro\nodal, Xtro\nodal1, Xtro\mstn.1, Xtro\bmp10, Xtro\bmp6, Xtro\inha" "Mmus\Bmp3, Mmus\Inhba, Mmus\Gdf9, Mmus\Bmp10, Mmus\Bmp15, Mmus\Lefty2, Mmus\Bmp2, Mmus\Gdf10, Mmus\Gdf6, Mmus\Tgfb1, Mmus\Inhbe, Mmus\Gdf3, Mmus\Bmp5, Mmus\Gdf11, Mmus\Gdf2, Mmus\Tgfb2, Mmus\Nodal, Mmus\Bmp7, Mmus\Amh, Mmus\Lefty1, Mmus\Gdf1, Mmus\Bmp8a, Mmus\Gdf7, Mmus\Inhbc, Mmus\Gdf15, Mmus\Bmp8b, Mmus\Tgfb3, Mmus\Inhbb, Mmus\Gdf5, Mmus\Inha, Mmus\Bmp4, Mmus\Bmp6, Mmus\Mstn" "Hsap\GDF3, Hsap\INHBB, Hsap\BMP15, Hsap\BMP8B, Hsap\GDF2, Hsap\GDF15, Hsap\BMP5, Hsap\NODAL, Hsap\BMP10, Hsap\BMP6, Hsap\INHA, Hsap\GDF7, Hsap\GDF1, Hsap\TGFB1, Hsap\GDF6, Hsap\BMP4, Hsap\GDF10, Hsap\BMP8A, Hsap\GDF9, Hsap\MSTN, Hsap\LEFTY2, Hsap\INHBE, Hsap\BMP3, Hsap\GDF11, Hsap\INHBC, Hsap\BMP2, Hsap\LEFTY1, Hsap\GDF5, Hsap\INHBA, Hsap\AMH, Hsap\BMP7, Hsap\TGFB3, Hsap\TGFB2" " embryonic stage | stage 12-14 , larval stage | third instar , embryonic stage | stage 10 , embryonic stage | stage >14 , embryonic stage | stage >=6 , embryonic stage--pupal stage , adult stage | male " " anterior embryonic/larval midgut

, dorsal mesothoracic disc | restricted

, amnioproctodeal invagination

, embryonic gastric caecum

, ectoderm

, embryonic/larval hindgut

, gastric caecum

, embryonic midgut | restricted

, embryonic central nervous system

, embryonic muscle system

, posterior embryonic/larval midgut

, embryonic/larval foregut

, eye-antennal disc | restricted

, ventral thoracic disc | restricted

, visceral mesoderm

, mesoderm

" " embryonic stage | stage 16 , embryonic stage | stage >=15 , larval stage | third instar , embryonic stage | stage 12-16 , embryonic stage | stage >7 " " embryonic/larval hindgut

, embryonic gastric caecum

, dorsal mesothoracic disc | restricted

, posterior embryonic/larval midgut

, motor neuron

, mesoderm

, embryonic central nervous system

, embryonic/larval foregut

, embryonic midgut | restricted

, anterior embryonic/larval midgut

, embryonic neuron

, ventral thoracic disc | restricted

, visceral mesoderm

, eye-antennal disc | restricted

" "viable,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,visible,neuroanatomy defective,RU486 conditional,lethal,developmental rate defective,neurophysiology defective,recessive,partially lethal - majority live,wild-type,lethal - all die before end of larval stage,some die during larval stage,somatic clone,female sterile,small body,decreased cell size,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,circadian rhythm defective" "wing vein,ectopic,wing disc,wing,adult brain,RU486 conditional,larva,fat body,type I bouton | third instar larval stage,female germline stem cell,heat sensitive,male germline stem cell,posterior crossvein,wing vein L5,wing vein L4,distal,testis,spermatocyte,bouton,synaptic vesicle,postsynaptic membrane,crossvein,scutellar bristle,macrochaeta,wing vein L2,eye,ommatidium,dorsocentral bristle,wing margin bristle,anterior crossvein,wing cell,submarginal cell,2nd posterior cell,dil cell,wing basal cell 2,3rd posterior cell,wing sensillum,vibrissae,mesothoracic bristle,metathoracic bristle,leg,hemocyte,imaginal disc,embryonic/larval cuticle,telson,embryonic/larval posterior spiracle,stigmatophore,midgut constriction 1,anterior embryonic/larval midgut,synapse & neuromuscular junction, with gbbUAS.cKa,synapse, with gbbUAS.cKa,embryonic/larval fat body,gastric caecum,wing blade,anterior compartment,somatic clone,wing vein L3,cell non-autonomous,embryonic/larval digestive system,embryonic/larval brain,wing basal cell 1,1st posterior cell,posterior compartment,synapse & neuromuscular junction, with gbb2/gbb1,synapse, with gbb2/gbb1,triple row,type I bouton,supernumerary | third instar larval stage,NMJ bouton,NMJ bouton | third instar larval stage" FBgn0267978 ap apterous http://flybase.org/reports/FBgn0267978 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay "muscle organ development ; GO:0007517 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay nervous system development ; GO:0007399 | inferred from mutant phenotype muscle organ development ; GO:0007517 | traceable author statement leg disc development ; GO:0035218 | inferred from mutant phenotype anatomical structure regression ; GO:0060033 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | non-traceable author statement wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | traceable author statement inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype nervous system development ; GO:0007399 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | traceable author statement larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement wing disc dorsal/ventral pattern formation ; GO:0048190 | traceable author statement wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" nucleus ; GO:0005634 | inferred from direct assay "ap, Ap, CG8376, S-2a, LIM, blt, Xa, trw, apterous, AP, Apt, neuro" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001781:Zinc finger, LIM-type, IPR009057:Homeobox domain-like" CG8376 11-Aug-17 DroID_v2017_08 "Drer\lhx2a, Drer\lhx9, Drer\lhx2b" - "Cele\lim-7, Cele\ttx-3" "Xtro\lhx9, Xtro\lhx2" "Mmus\Lhx9, Mmus\Lhx2" "Hsap\LHX9, Hsap\LHX2, Hsap\HESX1" "visible,recessive,female sterile,male sterile,viable,flightless,short lived,lethal,neuroanatomy defective,sterile,uncoordinated,increased cell death,dominant,reduced,mating defective,female,courtship behavior defective,male,some die during immature adult stage,heat sensitive,fertile,male fertile,female fertile,stress response defective,heat stress response defective,semi-fertile,partially,good,wild-type,partially lethal - majority live,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "nurse cell,adult corpus allatum,embryonic/larval fat body,ovary,wing,haltere,wing disc,dorsal/ventral compartment boundary,wing margin,direct flight muscle,basalar muscle 51,basalar muscle 52,muscle of first axillary 53,muscle of third axillary 54,indirect flight muscle,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,longitudinal connective,presumptive embryonic/larval central nervous system,axon,interneuron,embryonic protocerebrum,embryonic deuterocerebrum,embryonic/larval neuron,heat sensitive,wing margin bristle,tarsal segment 4,scutellum,pretarsus,egg chamber,hemolymph,corpus allatum,scutellar bristle,dorsocentral bristle,peritrophic membrane,abdominal 2 lateral transverse muscle 1,abdominal 3 lateral transverse muscle 1,abdominal 4 lateral transverse muscle 1,abdominal 5 lateral transverse muscle 1,abdominal 6 lateral transverse muscle 1,abdominal 7 lateral transverse muscle 1,abdominal 2 lateral transverse muscle 2,abdominal 3 lateral transverse muscle 2,abdominal 4 lateral transverse muscle 2,abdominal 5 lateral transverse muscle 2,abdominal 6 lateral transverse muscle 2,abdominal 7 lateral transverse muscle 2,abdominal 2 lateral transverse muscle 3,abdominal 3 lateral transverse muscle 3,abdominal 4 lateral transverse muscle 3,abdominal 5 lateral transverse muscle 3,abdominal 6 lateral transverse muscle 3,abdominal 7 lateral transverse muscle 3,scutum,mesothoracic tergum,dorsal triple row,medial triple row,ventral triple row,anterior supraalar bristle,posterior supraalar bristle,anterior postalar bristle,adult fat body,mesothoracic leg,metathoracic leg,wing pouch,male accessory gland,postalar bristle,posterior compartment,wing vein,embryonic/larval somatic muscle,abdominal 2 ventral acute muscle 3,abdominal 3 ventral acute muscle 3,abdominal 4 ventral acute muscle 3,abdominal 5 ventral acute muscle 3,abdominal 6 ventral acute muscle 3,abdominal 7 ventral acute muscle 3,costal cell,posterior notopleural bristle,posterior postalar bristle,posterior scutellar bristle,microchaeta & thorax,thorax,mesothoracic suture,macrochaeta & thorax | dorsal,dorsal compartment,A1-7 lateral transverse muscle,ectopic,ventral compartment,distal,somatic clone,A1-7 segment border muscle" FBgn0004666 sim single-minded http://flybase.org/reports/FBgn0004666 "FBgn0003333, FBgn0003409" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from physical interaction with tgo transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0000982 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with tgo sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with tgo" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay adult walking behavior ; GO:0007628 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement ectoderm development ; GO:0007398 | traceable author statement determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype ventral midline development ; GO:0007418 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype locomotion ; GO:0040011 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype" transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR001067 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "sim, SIM, 1479/04, 1330/08, 1111/10, 1110/04, 1050/13, 1034/02, 1002/10, 0953/08, 0899/14, 0716/08, 0483/09, S8, shm, l(3)S8, l(3)s8, schm, l(3)RD, l(3)E320, l(3)87Ea, CG7771, Sim, bHLHe16" "IPR000014:PAS domain, IPR001067:Nuclear translocator, IPR001610:PAC motif, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR013655:PAS fold-3, IPR013767:PAS fold, IPR011990:Tetratricopeptide-like helical domain" CG7771 11-Aug-17 DroID_v2017_08 "Drer\epas1a, Drer\sim2, Drer\sim1a, Drer\sim1b, Drer\arntl1b, Drer\npas1" - "Cele\hlh-34, Cele\cky-1" "Xtro\sim1, Xtro\arnt2, Xtro\sim2" "Mmus\Sim2, Mmus\Npas3, Mmus\Arnt2, Mmus\Npas1, Mmus\Sim1" "Hsap\NPAS1, Hsap\SIM1, Hsap\ARNT2, Hsap\SIM2, Hsap\NPAS3" " embryonic stage , embryonic stage | stage 10-12 " " ventral midline

, mesectoderm

, somatic mesoderm

, myoblast &&of larval muscle system

" " embryonic stage , embryonic stage | stage 10-15 " " ventral oblique muscle

, VUM neuron

, myoblast &&of larval muscle system

, somatic mesoderm

, neuroblast MNB

, midline glial cell

, embryonic foregut

ventral & anterior , mesectoderm

" "viable,fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective,lethal,heat sensitive,sterile,visible,courtship behavior defective,optomotor response defective,locomotor behavior defective,female sterile,male sterile,increased cell death,partially,decreased cell number,somatic clone,pair rule phenotype" "ventral arm of pharyngeal sclerite,embryonic head,embryonic epidermis,ventral nerve cord commissure,presumptive embryonic/larval central nervous system,anal slit,heat sensitive,genitalia,analia,optic chiasma,lobula,adult central complex,fan-shaped body,protocerebral bridge,longitudinal connective,female analia,adult hindgut,gonopod thorn bristle,vulva,ovary,anal plate,clasper,penis,testis,lamina forming neuroblast,embryonic/larval brain,eye photoreceptor cell & axon,ventral nerve cord,embryonic somatic muscle,ventral,embryonic central brain,ganglion mother cell GMC1-1a,RP2 motor neuron,ectopic,RP2sib neuron,embryonic ventral epidermis,ventral midline,commissure,neuromere,midline glial cell,MP1 neuron,abdominal 1 dorsal VUM motor neuron,abdominal 2 dorsal VUM motor neuron,abdominal 3 dorsal VUM motor neuron,abdominal 4 dorsal VUM motor neuron,abdominal 5 dorsal VUM motor neuron,abdominal 6 dorsal VUM motor neuron,abdominal 7 dorsal VUM motor neuron,abdominal 1 ventral VUM motor neuron,abdominal 2 ventral VUM motor neuron,abdominal 3 ventral VUM motor neuron,abdominal 4 ventral VUM motor neuron,abdominal 5 ventral VUM motor neuron,abdominal 6 ventral VUM motor neuron,abdominal 7 ventral VUM motor neuron,abdominal 1 lateral VUM motor neuron,abdominal 2 lateral VUM motor neuron,abdominal 3 lateral VUM motor neuron,abdominal 4 lateral VUM motor neuron,abdominal 5 lateral VUM motor neuron,abdominal 6 lateral VUM motor neuron,abdominal 7 lateral VUM motor neuron,neuroblast MNB,dorsal neurohemal organ,central nervous system,VUM precursor,MP1 precursor,embryonic/larval anal pad,genital disc primordium,muscle founder cell,adult salivary gland primordium,embryonic neuroblast,cell cycle,ventral nerve cord primordium & mitotic cell cycle,peripheral glial cell,neuroglioblast,medial-most cell body glial cell,medial cell body glial cell,exit glial cell,axon | somatic clone | third instar larval stage,denticle belt,ventral nervous system,ventral midline neuron,mesectoderm,cephalopharyngeal skeleton,dendritic arborizing neuron,axon,VUM interneuron 1,VUM interneuron 2,VUM interneuron 3,VUM neuron,macrophage,neuron,embryonic/larval cuticle,embryonic segment,embryonic brain,eye,adult head,antenna,trichogen cell" FBgn0011692 pav pavarotti http://flybase.org/reports/FBgn0011692 FBgn0022345 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" actomyosin contractile ring assembly ; GO:0000915 | inferred from electronic annotation with InterPro:IPR032924 plus-end-directed vesicle transport along microtubule ; GO:0072383 | inferred from electronic annotation with InterPro:IPR032924 somatic muscle development ; GO:0007525 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement actomyosin contractile ring assembly ; GO:0000915 | non-traceable author statement smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype inferred from genetic interaction with arm inferred from genetic interaction with tum peripheral nervous system development ; GO:0007422 | non-traceable author statement positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype microtubule bundle formation involved in mitotic spindle midzone assembly ; GO:1903562 | inferred from mutant phenotype cell fate determination ; GO:0001709 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 centrosome duplication ; GO:0051298 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype somatic ring canal ; GO:0098549 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay mitotic spindle midzone ; GO:1990023 | inferred from direct assay axoneme ; GO:0005930 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay contractile ring ; GO:0070938 | inferred from direct assay centrosome ; GO:0005813 | non-traceable author statement kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 male germline ring canal ; GO:0035323 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity spindle ; GO:0005819 | non-traceable author statement "2A12, Pav-KLP, group D, pav-Klp, Pav-klp, PAV/KLP, PAV-KLP, CG1258, anon2A12, DmKLP1/pav, PAV-MKLP, DmMKLP1, 2A12MEL, 0973/08, 0934/13, Mklp1, anon-EST:fe2A12, pav, Pav, Pav KLP, PAV, pav-KLP, Pav-Klp, PavKLP, DmPav, DmPAV, KIF 23, KIF23, kinesin-6" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR032384:Kinesin-like protein Kif23, Arf6-interacting domain, IPR032924:Kinesin-like protein KIF23" CG1258 11-Aug-17 DroID_v2017_08 "Drer\kif23, Drer\kcnh6b, Drer\kcnh2a, Drer\kif20ba, Drer\zgc:56231, Drer\kif20a, Drer\kcnh6a, Drer\kcnh7" Scer\KIP2 "Cele\unc-103, Cele\zen-4" "Xtro\kif23, Xtro\kif20a, Xtro\kcnh6, Xtro\kcnh7" "Mmus\Kcnh7, Mmus\Kif20a, Mmus\Kif23, Mmus\Kcnh6, Mmus\Kif20b, Mmus\Kcnh2" "Hsap\KIF20A, Hsap\KCNH6, Hsap\KIF20B, Hsap\KCNH2, Hsap\KIF23" " , embryonic stage | embryonic cycle 16 , adult stage " " cell

, organism

, stage S7 oocyte

, egg chamber && ring canal

, nurse cell

" "cytokinesis defective,neuroanatomy defective,recessive,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,meiotic cell cycle defective,dominant,wild-type,somatic clone,mitotic cell cycle defective,female sterile,viable,fertile,female fertile,visible" "nucleus,ventral nerve cord,embryonic epidermis,nucleusGN50),S2 cell-line,perinuclear region of cytoplasm,neuron,presumptive embryonic/larval peripheral nervous system,cycle 16 embryo,spindle,mitosis & nuclear chromosome,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,neuron & peripheral nervous system,mitotic telophase,mitotic telophase & spindle,actomyosin contractile ring,mushroom body & axon | somatic clone,microtubule,spindle | embryonic cycle 16,centrosome | embryonic cycle 16,abdominal ventral denticle belt,embryonic/larval somatic muscle,egg chamber,oocyte,nurse cell & microtubulemat.‘±Tub67C.THsimVP16,ring canal,actin filament & nurse cellmat.‘±Tub67C.THsimVP16,nurse cell,egg,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC08730 I 2.426854294 -0.330624867 0.773645307 -0.745803994 -0.35855974 0.988264344 FBgn0015790 Rab11 Rab11 http://flybase.org/reports/FBgn0015790 "FBgn0004235, FBgn0011334" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTPase activating protein binding ; GO:0032794 | inferred from physical interaction with Crag protein binding ; GO:0005515 | inferred from physical interaction with Sec5 protein binding ; GO:0005515 | inferred from physical interaction with Rip11 protein complex binding ; GO:0032403 | inferred from physical interaction with Sec15 GTPase activity ; GO:0003924 | inferred from mutant phenotype GTPase activating protein binding ; GO:0032794 | inferred from physical interaction with Evi5 protein binding ; GO:0005515 | inferred from physical interaction with Sbf" "adherens junction maintenance ; GO:0034334 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype fusome organization ; GO:0045478 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype centrosome localization ; GO:0051642 | inferred from mutant phenotype Golgi vesicle fusion to target membrane ; GO:0048210 | inferred from mutant phenotype dorsal closure, elongation of leading edge cells ; GO:0007394 | inferred from mutant phenotype dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype exosomal secretion ; GO:1990182 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype positive regulation of Golgi to plasma membrane protein transport ; GO:0042998 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from direct assay endocytosis ; GO:0006897 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype Rab protein signal transduction ; GO:0032482 | inferred from direct assay cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from genetic interaction with Rho1 ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from genetic interaction with bchs border follicle cell migration ; GO:0007298 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype spermatocyte division ; GO:0048137 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay endosome ; GO:0005768 | inferred from direct assay vesicle ; GO:0031982 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay spindle envelope ; GO:0070732 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay recycling endosome ; GO:0055037 | colocalizes_with inferred from direct assay cell pole ; GO:0060187 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay trans-Golgi network transport vesicle ; GO:0030140 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay microtubule organizing center ; GO:0005815 | colocalizes_with inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay autophagosome ; GO:0005776 | inferred from direct assay centrosome ; GO:0005813 | colocalizes_with inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay Golgi trans cisterna ; GO:0000138 | "Rab11, Dm Rab11, rab11, AAF55850, DmRab11, rab-11, CG5771, Drab11, l(3)j2D1, l(3)93Bi, DRab11, DRAB11, rlr7, Rab-r11, Rab 11, RAB11, Rab-11, O18335, dRab11" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5771 11-Aug-17 DroID_v2017_08 "Drer\rab11bb, Drer\rab25b, Drer\rab11a, Drer\rab25a, Drer\rabl2, Drer\rab11ba, Drer\rab11al" "Scer\YPT32, Scer\YPT31, Scer\YPT11" "Cele\rab-11.1, Cele\rab-11.2" "Xtro\rabl2b, Xtro\rab11b.1, Xtro\rab11b.2, Xtro\rab25, Xtro\rab11a" "Mmus\Rab11a, Mmus\Rab25, Mmus\Rab11b, Mmus\Rabl2" "Hsap\RAB11A, Hsap\RAB25, Hsap\RABL2A, Hsap\RABL2B, Hsap\RAB11B" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "female semi-sterile,female sterile,partially lethal - majority die,meiotic cell cycle defective,male,cytokinesis defective,recessive,visible,fertile,lethal,neuroanatomy defective,viable,size defective,cell migration defective,cell lethalcell lethal,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,increased cell death,neurophysiology defective,conditional,sterile" "macrochaeta,actin cytoskeleton | embryonic stage,spermatid,Nebenkern,nucleus | embryonic stage,germline cell,acroblast,spindle,contractile ring,cleavage furrow,Golgi-associated vesicle,neuromuscular junction,NMJ bouton,supernumerary,microchaeta,posterior scutellar bristle,bouton,border follicle cell,embryonic/first instar larval cuticle,embryonic leading edge cell,optic cartridge | third instar larval stage,eye,photoreceptor | third instar larval stage,ommatidium | third instar larval stage,egg chamber,germline clone,rhabdomere,somatic clone,multivesicular body & eye photoreceptor cell | somatic clone[-],dorsocentral bristle,scutellar bristle,tormogen cell,embryonic dorsal epidermis,amnioserosa,interommatidial bristle,eye photoreceptor cell,ommatidium,fusome | germline clone,germline stem cell,egg,female germline stem cell,cell-cell adherens junction | somatic clone,stem cell fusome,nurse cell ring canal,female germline cyst,oocyte,rhabdomerehs.PB,wing hair | pupal stage,multivesicular bodyhs.PB,photoreceptor cell,garland cell,embryonic/larval dorsal trunk,syncytial blastoderm embryo,adult midgut epithelium,chaeta & antenna,eye disc,cone cell,primary pigment cell,trichogen cell,socket,rhabdomere | conditionalninaE.PT,chaeta,mesothoracic tergum,wing,wing vein,wing hair,macrophage,centrosomeneur-P72,external sensory organ precursor cell I,epithelium" DRSC16809 I 0.89443948 -1.50747614 -0.569862749 -0.333742244 0.205974943 0.826598135 FBgn0015371 chn charlatan http://flybase.org/reports/FBgn0015371 "FBgn0010506, FBgn0026007, FBgn0033992, FBgn0046116" protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with CoRest transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype progression of morphogenetic furrow involved in compound eye morphogenesis ; GO:0007458 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with para embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype negative regulation of compound eye cone cell fate specification ; GO:0042683 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred by curator from GO:0003705 "chn, CG11798, l(2)k04218, l(2)02064, clone 1.13, EPIL#6, taco, anon-EST:Liang-1.13, EPIL6, Chn" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013087:Zinc finger C2H2-type" CG11798 11-Aug-17 DroID_v2017_08 - - - - - - "neuroanatomy defective,visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,heat sensitive,viable" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,macrochaeta,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,cone cell,eye,chaeta,supernumerary,mesothoracic tergum,eye photoreceptor cell,somatic clone,wing disc,morphogenetic furrow,external sensory organ,ectopic,mesothoracic bristle,ventral abdominal cluster,dorsal abdominal cluster,chordotonal organ & neuron,mesothoracic tergum & macrochaeta | somatic clone,scutellar bristle,trichogen cell,dorsal mesothoracic disc & sensory mother cell | somatic clone,heart primordium,mesothoracic tergum & macrochaeta-537.4,anterior notopleural bristle,posterior notopleural bristle,posterior supraalar bristle,anterior postalar bristle,posterior postalar bristle,dorsocentral bristle,mesothoracic tergum & macrochaetaap-md544,anterior supraalar bristle,microchaeta,wing & chaeta | ectopicC-765,mesothoracic tergum & macrochaeta | ectopicMS248,head bristle,dorsal mesothoracic disc & sensory mother cell | ectopicMS248,metathoracic bristle,wing & chaeta | ectopicBx-MS1096,dorsal mesothoracic disc & sensory mother cell | ectopicBx-MS1096,sensory neuron,embryonic/larval hemocyte | third instar larval stage" DRSC06086 E 1.004031126 -0.66729064 1.900963321 1.596566217 -0.290107229 -0.428332752 FBgn0003525 stg string http://flybase.org/reports/FBgn0003525 "FBgn0011019, FBgn0011315, FBgn0011317, FBgn0011354, FBgn0011428, FBgn0043376" protein_coding_gene protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay "positive regulation of cell cycle G2/M phase transition ; GO:1902751 | inferred from electronic annotation with InterPro:IPR000751 protein dephosphorylation ; GO:0006470 | inferred from direct assay open tracheal system development ; GO:0007424 | traceable author statement positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from sequence or structural similarity Golgi organization ; GO:0007030 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement G2/M transition of mitotic cell cycle ; GO:0000086 | traceable author statement mesoderm development ; GO:0007498 | traceable author statement G2/M transition of mitotic cell cycle ; GO:0000086 | non-traceable author statement mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype gastrulation ; GO:0007369 | non-traceable author statement histoblast morphogenesis ; GO:0007488 | inferred from mutant phenotype positive regulation of mitotic cell cycle, embryonic ; GO:0045977 | inferred from mutant phenotype regulation of cell diameter ; GO:0060305 | inferred from mutant phenotype negative regulation of mitotic cell cycle ; GO:0045930 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement gastrulation ; GO:0007369 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype positive regulation of mitotic cell cycle ; GO:0045931 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype" chromosome ; GO:0005694 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "stg, cdc25, str/cdc25, cdc25[string], CDC25[string], stg[cdc25], Cdc25, CG1395, Cdc25[String], String/Cdc25, SY3-4, l(3)01235, clone 2.21, Cdc25[stg], 5473, 1143/02, 1089/08, 1083/13, 0980/06, 0967/05, 0896/05, 0730/13, 0439/22, 0245/03, 0224/06, Cdc25[string], S(rux)3A, EP1213, l(3)s2213, l(3)j3D1, l(3)j1E3, l(3)j1D3, l(3)j10B9, anon-EST:Liang-2.21, Stg, string, Cdc25c, CDC25, Cdc25[Stg], STG, st" "IPR000751:M-phase inducer phosphatase, IPR001763:Rhodanese-like domain" CG1395 11-Aug-17 DroID_v2017_08 "Drer\cdc25b, Drer\cdc25d" "Scer\ARR2, Scer\YCH1, Scer\MIH1" "Cele\cdc-25.1, Cele\cdc-25.3, Cele\cdc-25.2, Cele\cdc-25.4" "Xtro\cdc25c, Xtro\cdc25a, Xtro\cdc25b" "Mmus\Cdc25c, Mmus\Cdc25a, Mmus\Cdc25b" "Hsap\CDC25A, Hsap\CDC25B, Hsap\CDC25C" " spermatogenesis && adult stage , embryonic stage | stage >=10 , larval stage , adult stage && oogenesis stage , embryonic stage | early , adult stage | female " " testis

, Malpighian tubule | restricted

, eye-antennal disc

, oocyte

, nurse cell

, optic lobe

" "female sterile,lethal,recessive,viable,female fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,fertile,size defective,dominant,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,visible,wild-type,mitotic cell cycle defective,increased cell size,male sterile,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die during pupal stage,decreased cell size,cell shape defective,increased cell number" "wing blade,macrochaeta,ventral nerve cord commissure,longitudinal connective,scutellar bristle,eye,haltere,wing,embryonic/first instar larval cuticle,denticle belt,crystal cell,mitotic cell cycle,plasmatocyte,trichogen cell,ectopic,tormogen cell,thecogen cell,ommatidium,eye photoreceptor cell,eye disc,photoreceptor cell,photoreceptor cell R2,photoreceptor cell R5,germline cyst,cystocyte,ventral furrow,ganglion mother cell,mitotic cell cycle | ectopic,wing disc,eye-antennal disc,scutum & macrochaeta,ganglion mother cell GMC4-2a,RP2sib neuron,aCC neuron,precursor,pCC neuron,macrochaeta & adult head,macrochaeta & adult thorax,macrochaeta & scutellum,macrochaeta & wing,nuclear chromosome,nuclear membrane,spindle,larval hindgut & ectoderm,neuron,presumptive embryonic/larval peripheral nervous system,embryonic/larval brain,socket,mitotic cell cycle | embryonic stage,neuropil,embryonic/larval hindgut,microchaeta,sensory mother cell,somatic clone,cell cycle,mitotic cell cycle | somatic clone,glial cell & eye disc | ectopicbi-omb-Gal4,spermatogonial cyst,oocyte,chaeta,wing cell,mitotic cell cycle & eye disc,imaginal disc,multidendritic neuron,external sensory organ,chordotonal organ,follicle cell,embryonic neuroblast,cycle 14 embryo,centriole,neuroblast NB6-4 of thorax,neuroblast NB6-4 of abdomen,cardioblast,pericardial cell,embryo" DRSC17071 EK -1.183141306 -1.478998275 -0.842647849 -3.720270765 8.759802607 12.04724024 FBgn0000097 aop anterior open http://flybase.org/reports/FBgn0000097 "FBgn0003123, FBgn0005623, FBgn0026827" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418, InterPro:IPR003118 protein binding ; GO:0005515 | inferred from physical interaction with edl transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay protein domain specific binding ; GO:0019904 | inferred from physical interaction with Fbl6" "endocytosis ; GO:0006897 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype dorsal closure ; GO:0007391 | non-traceable author statement determination of adult lifespan ; GO:0008340 | inferred from genetic interaction with pnt inferred from genetic interaction with foxo border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | non-traceable author statement neuron development ; GO:0048666 | inferred from mutant phenotype regulation of establishment of planar polarity ; GO:0090175 | inferred from genetic interaction with dgo JNK cascade ; GO:0007254 | non-traceable author statement cell fate determination ; GO:0001709 | inferred from mutant phenotype oenocyte delamination ; GO:0060233 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | inferred from mutant phenotype muscle fiber development ; GO:0048747 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement negative regulation of cell differentiation ; GO:0045596 | non-traceable author statement regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype negative regulation of photoreceptor cell differentiation ; GO:0046533 | traceable author statement negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype inferred from genetic interaction with Ras85D inferred from genetic interaction with chico MAPK cascade ; GO:0000165 | traceable author statement R7 cell development ; GO:0045467 | traceable author statement negative regulation of fusion cell fate specification ; GO:0035157 | inferred from mutant phenotype positive regulation of R7 cell differentiation ; GO:0045678 | inferred from genetic interaction with alph" nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Yan, AOP, YAN, yan, Aop, CG3166, Aop/Yan, DROYANETSB, SK2-1, DROYANET, aop/yan, pok, yan/pok, aop, fus6" "IPR013761:Sterile alpha motif/pointed domain, IPR000418:Ets domain, IPR003118:Pointed domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR033077:Ets DNA-binding protein pokkuri" CG3166 11-Aug-17 DroID_v2017_08 "Drer\etv4, Drer\elf2a, Drer\ehf, Drer\ef1, Drer\etv1, Drer\etv5a, Drer\etv5b, Drer\etv6, Drer\etv7, Drer\elf2b" - "Cele\ets-8, Cele\elf-1, Cele\ets-9" "Xtro\ehf, Xtro\elf1, Xtro\elf2, Xtro\etv6" "Mmus\Elf1, Mmus\Etv5, Mmus\Elf5, Mmus\Elf4, Mmus\Etv1, Mmus\Elf3, Mmus\Etv4, Mmus\Elf2, Mmus\Ehf, Mmus\Etv6" "Hsap\ELF1, Hsap\EHF, Hsap\ELF5, Hsap\ELF4, Hsap\ETV6, Hsap\ETV4, Hsap\ETV7, Hsap\ELF2, Hsap\ETV1, Hsap\ETV5, Hsap\ELF3" " larval stage | third instar , embryonic stage " imaginal disc

" pupal stage , embryonic stage | stage 10 , larval stage , embryonic stage | stage 13 " " pigment cell

, epidermis

, eye-antennal disc

, embryonic/larval tracheal system

, cone cell

" "lethal,viable,visible,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,poor,sterile,partially,planar polarity defective,polyphasic,partially lethal - majority die,female sterile,male sterile,reduced,somatic clone,heat sensitive,increased cell death,neuroanatomy defective,size defective" "scutellar bristle,ectopic,tormogen cell,trichogen cell,adult abdomen & trichogen cell-537.4,wing,wing vein,border follicle cell,somatic clone,presumptive embryonic/larval muscle system,photoreceptor cell R7,eye,ommatidium,eye photoreceptor cell,supernumerary,posterior compartment,midline glial cell,cone cell,precursor,cell autonomous,embryonic/larval tracheal system,embryonic somatic muscle,segment border muscle,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,embryonic/larval oenocyte,gonad,gonadal sheath proper primordium,tarsal segment,denticle,embryonic/first instar larval cuticle,embryonic epidermis,anterior,dorsal,lch5 neuron,eye disc,photoreceptor cell R8,heat sensitive,photoreceptor cell,macrochaeta & eye,pigment cell,mesoderm,embryonic/larval pericardial cell,A1-7 dorsal acute muscle 1,abdominal lateral pentascolopidial chordotonal organ lch5,chordotonal organ,follicle cell,tracheal lumen,embryonic/larval dorsal trunk,tracheal fusion cell,terminal tracheal cell,cephalopharyngeal skeleton,dorsal pouch,eye-antennal disc,visual primordium,stomatogastric nervous system,Bolwig organ,rhabdomere,endocytic vesicle,embryonic/larval ganglionic branch,presumptive embryonic/larval central nervous system,wing disc,macrochaeta,morphogenetic furrow,embryonic dorsal epidermis,sensory neuron & axon & embryorepo,motor neuron | embryonic stage,presumptive embryonic/larval peripheral nervous system,fascicle | embryonic stage,embryo,embryonic/larval dorsal vessel | embryonic stage,embryonic/larval somatic muscle,commissure,longitudinal connective,denticle row 1,cardiogenic mesoderm,melanotic mass,hemocyte,lamellocyte,crystal cell,muscle fiber,muscle founder cell,interommatidial bristle,secondary neuroblast,ectopic | larval stage" FBgn0002521 pho pleiohomeotic http://flybase.org/reports/FBgn0002521 "FBgn0005575, FBgn0024914" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VDY1 DNA binding ; GO:0003677 | traceable author statement DNA binding ; GO:0003677 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay chromatin DNA binding ; GO:0031490 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay "DNA topological change ; GO:0006265 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | non-traceable author statement chromatin remodeling ; GO:0006338 | inferred by curator from GO:0031011 gene silencing ; GO:0016458 | inferred from direct assay chromatin silencing ; GO:0006342 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from direct assay" polytene chromosome puff ; GO:0005703 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from direct assay PcG protein complex ; GO:0031519 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay Ino80 complex ; GO:0031011 | inferred from direct assay "Pho, PHO, CG17743, l(4)pho, YY1, l(4)102EFc, l(4)29, l(4)OC-1, l(4)BU-2, pho, dYY1, PHO/YY1" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17743 11-Aug-17 DroID_v2017_08 "Drer\sall3a, Drer\znf644b, Drer\si:dkeyp-84f3.5, Drer\yy1a, Drer\znf367, Drer\zfx, Drer\yy1b, Drer\sall1a" "Scer\NRG2, Scer\CMR3, Scer\NRG1" "Cele\ztf-17, Cele\sem-4, Cele\hbl-1, Cele\K11D2.4" "Xtro\yy1, Xtro\rest, Xtro\gzf1, Xtro\sall1, Xtro\sall3, Xtro\znf644" "Mmus\Zfp101, Mmus\Zfp473, Mmus\Yy1, Mmus\Zfp202, Mmus\Gm13212, Mmus\Zfp367, Mmus\Zfp644, Mmus\Zfp42, Mmus\Zfp37, Mmus\Sall3, Mmus\Yy2, Mmus\Zbtb6, Mmus\Zim1, Mmus\Zfp13, Mmus\Zfp984, Mmus\Sall1" "Hsap\YY2, Hsap\ZNF680, Hsap\SALL3, Hsap\ZNF347, Hsap\ZNF367, Hsap\ZNF644, Hsap\SP1, Hsap\ZNF540, Hsap\ZNF543, Hsap\ZFP42, Hsap\ZNF682, Hsap\SALL1, Hsap\YY1, Hsap\ZNF555" "neuroanatomy defective,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,wild-type" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,antenna,sex comb,unguis,mesothoracic leg,metathoracic leg,tarsal segment,pupal abdomen,female accessory gland,embryonic head,maternal effect,embryonic thorax,embryonic abdominal segment 6,embryonic abdominal segment 7,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,adult abdominal segment 4,embryonic abdominal segment,embryonic abdominal segment 8,ectopic,embryonic thoracic segment" FBgn0000635 Fas2 Fasciclin 2 http://flybase.org/reports/FBgn0000635 "FBgn0026682, FBgn0027230, FBgn0028323, FBgn0040201, FBgn0040202" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Appl "regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Egfr inferred from genetic interaction with aos inferred from genetic interaction with sty axonal fasciculation ; GO:0007413 | traceable author statement regulation of synapse structure or activity ; GO:0050803 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype learning or memory ; GO:0007611 | non-traceable author statement olfactory learning ; GO:0008355 | traceable author statement photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype cell morphogenesis involved in neuron differentiation ; GO:0048667 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | non-traceable author statement learning ; GO:0007612 | traceable author statement synapse organization ; GO:0050808 | inferred from mutant phenotype short-term memory ; GO:0007614 | traceable author statement regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | traceable author statement regulation of tube architecture, open tracheal system ; GO:0035152 | traceable author statement neuromuscular junction development ; GO:0007528 | traceable author statement negative regulation of neuron remodeling ; GO:1904800 | inferred from mutant phenotype neuron recognition ; GO:0008038 | inferred from direct assay homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay Bolwig's organ morphogenesis ; GO:0001746 | inferred from expression pattern inferred from mutant phenotype regulation of synaptic plasticity ; GO:0048167 | inferred from genetic interaction with Csk imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype" muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay postsynaptic membrane ; GO:0045211 | traceable author statement presynaptic membrane ; GO:0042734 | inferred from mutant phenotype presynaptic periactive zone ; GO:0036062 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay type I terminal bouton ; GO:0061174 | inferred from direct assay presynaptic membrane ; GO:0042734 | traceable author statement integral component of membrane ; GO:0016021 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay cell projection ; GO:0042995 | inferred from direct assay axon ; GO:0030424 | traceable author statement neuron projection ; GO:0043005 | inferred from direct assay postsynaptic membrane ; GO:0045211 | colocalizes_with inferred from direct assay terminal bouton ; GO:0043195 | plasma membrane ; GO:0005886 | "FasII, Fas2, fasII, Fas II, mAb 1D4, 1D4, mAb1D4, fas2, CT12301, FASII, FAS II, Ab 1D4, fas II, CG3665, mAB1D4, clone 1.60, FascII, fas-II, l(1)G0032, l(1)G0048, l(1)G0081, l(1)G0293, l(1)G0336, anon-EST:Liang-1.60, EG:EG0007.3, FAS2, Fas, MAB1D4, FAS 11, Fasii, Fas 2, Fas-II, fasciclin II" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR009138:Neural cell adhesion, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG3665 11-Aug-17 DroID_v2017_08 "Drer\zgc:152904, Drer\ncam1b, Drer\ncam1a, Drer\il1rapl1a, Drer\LOC799279, Drer\vsig8b, Drer\il1rapl1b, Drer\ncam3, Drer\ncam2, Drer\il1rapl2" - Cele\ncam-1 "Xtro\il1r2, Xtro\ncam1, Xtro\ncam2" "Mmus\Il1rap, Mmus\Il1r1, Mmus\Il18r1, Mmus\Il1rapl1, Mmus\Il1rl2, Mmus\Ncam1, Mmus\Ncam2, Mmus\Il18rap, Mmus\Il1rapl2, Mmus\Il1r2, Mmus\Il1rl1" "Hsap\IL1RAPL2, Hsap\IL1RL2, Hsap\IL1RAPL1, Hsap\IL18RAP, Hsap\IL1RL1, Hsap\IL1RAP, Hsap\NCAM2, Hsap\IL1R1, Hsap\NCAM1, Hsap\IL18R1, Hsap\IL1R2" " embryonic stage | stage 9-11 , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 14-16 , embryonic stage | stage 16 , embryonic stage | stage 13-16 , embryonic stage | stage 13 " " tritocerebral neuroblast | subset

, ectoderm | restricted

, procephalic neurogenic region | restricted

, aCC neuron

, pCC neuron

, intersegmental nerve

, inclusive hindgut primordium

, sensory neuron

, peripheral nervous system | restricted

, longitudinal connective

, embryonic/larval spiracle | precursor

, Malpighian tubule

, neuron

, vMP2 neuron

, dMP2 neuron

, deuterocerebral neuroblast | subset

, MP1 neuron

" "viable,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,male,female,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,male sterile,visible,neuroanatomy defective,poor,fertile,recessive,wild-type,partially,cold sensitive,dominant,neurophysiology defective,learning defective,memory defective,lethal - all die before end of larval stage,some die during larval stage,uncoordinated,somatic clone" "wing,chaeta,ejaculatory duct,male genitalia,embryonic/larval corpus allatum,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary,eye-antennal disc,anterior crossvein,eye,NMJ bouton | third instar larval stage,indirect flight muscle motor neuron MN5,neuromuscular junction,mechanosensory neuron,eye photoreceptor cell,cone cell,ommatidium,NMJ bouton,synapse,MP1 neuron,dMP2 neuron,vMP2 neuron,Bolwig organ,photoreceptor,postvertical bristle,RP3 motor neuron,motor neuron,neuromuscular junction | larval stage,bouton,supernumerary,lobe system of adult mushroom body,border follicle cell,synapse | ectopic,calyx of adult mushroom body,somatic clone,ocellar bristle,anterior vertical bristle,posterior vertical bristle,ocellus,anterior orbital bristle,middle orbital bristle,posterior orbital bristle,thorax & macrochaeta | somatic clone,thorax & microchaeta | somatic clone,ganglionic branch primordium,presumptive embryonic/larval tracheal system,fascicle & mushroom body | somatic clone,synapse & aCC neuron,synapse & RP2 neuron,dorsal trunk primordium,U neuron & growth cone,photoreceptor cell R8,photoreceptor cell R7,cell non-autonomous,dorsocentral bristle,external sensory organ precursor cell,photoreceptor | embryonic stage,abdominal segmental nerve | embryonic stage,abdominal ventral muscle | embryonic stage,abdominal intersegmental nerve,synapse & abdominal 2 ventral longitudinal muscle 1,synapse & abdominal 3 ventral longitudinal muscle 1,synapse & abdominal 4 ventral longitudinal muscle 1,synapse & abdominal 5 ventral longitudinal muscle 1,synapse & abdominal 6 ventral longitudinal muscle 1,synapse & abdominal 7 ventral longitudinal muscle 1,adult neuromuscular junction,abdominal segmental nerve,adult mushroom body,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,macrochaeta,axon & eye photoreceptor cellGMR.PF,axon & laminaGMR.PF,eye photoreceptor cell & laminaGMR.PF,synapse & aCC neuroneve.RRK,synapse & RP2 neuroneve.RRK,synapse & RP2 neuronB19,synapse & aCC neuronB19,synapse & RP3 neuronB19, eve.RRK,transverse nerve,synapse | ectopicl(3)H94-H94,synapsel(3)H94-H94,RP1 motor neuron,RP5 motor neuron,synapse | ectopichow-24B,synapse | ectopicl(2)E105-E105,synapse | ectopicB185,synapse | ectopicMhc.PW,synapse | ectopicelav.PLu,ocellar nerve,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,RP2 motor neuron,neuromuscular junctionfutsch-C380,neuromuscular junctionBG487,follicle cell,trichogen cell,mushroom body beta-lobe" DRSC17309 EK 0.022361657 -0.924260746 -1.008634496 1.811476752 -0.397387001 -1.998957551 FBgn0015664 Dref DNA replication-related element factor http://flybase.org/reports/FBgn0015664 FBgn0010077 protein_coding_gene "transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001512074 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from physical interaction with Trf2 calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProtKB:Q96RR4" "mitochondrial DNA replication ; GO:0006264 | traceable author statement regulation of apoptotic process ; GO:0042981 | inferred from direct assay regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of DNA biosynthetic process ; GO:2000278 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:Q96RR4 protein autophosphorylation ; GO:0046777 | inferred from sequence or structural similarity with UniProtKB:Q96RR4 DNA replication ; GO:0006260 | traceable author statement transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype sensory organ precursor cell division ; GO:0045035 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype regulation of mitochondrial depolarization ; GO:0051900 | inferred from mutant phenotype regulation of cell proliferation involved in compound eye morphogenesis ; GO:2000495 | inferred from direct assay regulation of cell cycle ; GO:0051726 | non-traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with Trf2 "DREF, DmDREF, p80/DREF, p80, dDREF, CG5838, Dref, dref, Dmel_DREF" "IPR003656:Zinc finger, BED-type, IPR013087:Zinc finger C2H2-type, IPR012337:Ribonuclease H-like domain" CG5838 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-152f22.4, Drer\si:dkey-13n23.3, Drer\zbed4, Drer\zgc:161969, Drer\mybl2a" - - Xtro\LOC100486384 - "Hsap\ZBED1, Hsap\DHRSX, Hsap\ZNF618" embryonic stage -- adult stage "viable,visible,lethal,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,endomitotic cell cycle defective,neuroanatomy defective,fertile,increased cell death,mitotic cell cycle defective" "photoreceptor cell,pigment cell,eye,wing,wing vein L5,melanotic mass,wing margin bristle,somatic clone,macrochaeta,posterior scutellar bristle,anterior scutellar bristle,posterior dorsocentral bristle,anterior dorsocentral bristle,posterior notopleural bristle,presutural bristle,external sensory organ precursor cell,trichogen cell,tormogen cell,nucleus-109-68,nucleolus-109-68,microchaeta,adult thorax,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,embryonic/larval salivary gland | embryonic stage,eye disc,ommatidium,interommatidial bristle,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,scutellar bristle,ectopic,posterior compartment,wing disc,distal,dorsal,wing margin,embryonic/larval neuroblast,ganglion mother cell,ventral multidendritic neuron vdaB" DRSC03319 E 0.200008925 -0.383619684 -0.603067841 -4.339691553 -0.764175801 0.112028007 FBgn0000576 ems empty spiracles http://flybase.org/reports/FBgn0000576 FBgn0000145 protein_coding_gene RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 open tracheal system development ; GO:0007424 | inferred from expression pattern inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype anterior head segmentation ; GO:0035288 | traceable author statement embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype brain segmentation ; GO:0035284 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype pattern specification process ; GO:0007389 | non-traceable author statement brain development ; GO:0007420 | non-traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "E4, ant, W13, CG2988, ems, Ems, EMS, empty spiracles" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG2988 11-Aug-17 DroID_v2017_08 "Drer\vax2, Drer\emx3, Drer\noto, Drer\emx2, Drer\emx1, Drer\vax1, Drer\nkx3.2, Drer\nkx3.3" - "Cele\egl-5, Cele\ceh-16, Cele\ceh-2" "Xtro\emx1.2, Xtro\vax1, Xtro\emx2, Xtro\wipf1, Xtro\not" "Mmus\Vax2, Mmus\Emx1, Mmus\Nkx3-2, Mmus\Noto, Mmus\Vax1, Mmus\Emx2, Mmus\Nkx6-1" "Hsap\VAX1, Hsap\NKX1-1, Hsap\NKX6-1, Hsap\EMX2, Hsap\NOTO, Hsap\VAX2, Hsap\NKX3-2, Hsap\EMX1" " embryonic stage | stage 13 , embryonic stage | stage 6,7 , embryonic stage , embryonic stage | stage >=8 , embryonic stage | stage 4 , embryonic stage | stage >=7 , embryonic stage | stage >=9 , embryonic stage | stage 14 , embryonic stage--pupal stage , embryonic stage -- adult stage , embryonic stage | stage 12 , embryonic stage | stage 5 " " embryonic central nervous system | lateral

, cephalic furrow

, antenno-maxillary complex

,

segment polarity , organism | 70-90% egg length

, antennal segment

, embryonic/larval posterior spiracle

, mandibular segment

, intercalary segment

, subesophageal ganglion

, procephalic segment

, cephalic furrow | anterior to

, larval optic lobe | primordium

, organism | 70-80% egg length

" " embryonic stage | blastoderm , embryonic stage | stage 9-11 , embryonic stage " " head

, deuterocerebral neuroblast | subset

, protocerebral neuroblast | subset

, tritocerebral neuroblast | subset

, neuroblast

, ectoderm

, filzkorper

{ - bcd- } , procephalic neurogenic region | restricted

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,increased cell death,somatic clone,neuroanatomy defective,viable" "embryonic head,filzkorper,embryonic/larval antennal segment sensillum,central nervous system,cephalopharyngeal skeleton,embryonic mandibular segment,dorsolateral papilla,ectopic,Bolwig organ,dorsomedial papilla,hypocerebral ganglion,embryonic/larval optic lobe,associated organ,mandibular segment,intercalary segment,antennal segment,ocular segment,antennal sense organ,spiracular chamber,stigmatophore,neuroblast,somatic clone,adult brain,embryonic/larval brain,neurite,cell autonomous,fascicle,antennal lobe projection neuron lPN,antennal lobe projection neuron adPN,adult antennal lobe projection neuron VA1v adPN,adult antennal lobe projection neuron VA3 adPN,adult antennal lobe projection neuron VM2 adPN,antennal lobe,local interneuron of larval antennal lobe,tracheal primordium,visceral branch primordium,dorsal branch primordium,ganglionic branch primordium,ventral nerve cord,ventral nerve cord commissure,longitudinal connective,deuterocerebral neuromere,tritocerebral neuromere,embryonic deuterocerebrum,embryonic tritocerebrum,embryonic head epidermis,vertical bridge,lateral process,dorsal bridge,embryonic/larval pharynx,maxillary lobe,cervical connective,adult antennal lobe projection neuron DL1 adPN" FBgn0004652 fru fruitless http://flybase.org/reports/FBgn0004652 "FBgn0000728, FBgn0001076, FBgn0012048, FBgn0038623, FBgn0038624, FBgn0038625" protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "male courtship behavior, veined wing vibration ; GO:0016545 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | traceable author statement male courtship behavior ; GO:0008049 | inferred from mutant phenotype mating behavior, sex discrimination ; GO:0048047 | traceable author statement aggressive behavior ; GO:0002118 | inferred from mutant phenotype mating behavior, sex discrimination ; GO:0048047 | inferred from mutant phenotype multicellular organism development ; GO:0007275 | inferred from mutant phenotype mating behavior, sex discrimination ; GO:0048047 | inferred from mutant phenotype inferred from genetic interaction with Tbh male courtship behavior ; GO:0008049 | non-traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype central nervous system development ; GO:0007417 | traceable author statement sex determination ; GO:0007530 | inferred from mutant phenotype male sex differentiation ; GO:0046661 | traceable author statement male courtship behavior, orientation prior to leg tapping and wing vibration ; GO:0016543 | non-traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | traceable author statement male mating behavior ; GO:0060179 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 copulation ; GO:0007620 | non-traceable author statement mating behavior ; GO:0007617 | inferred from mutant phenotype sex determination ; GO:0007530 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype male courtship behavior, veined wing extension ; GO:0048065 | inferred from mutant phenotype mating ; GO:0007618 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype central nervous system neuron development ; GO:0021954 | inferred from direct assay copulation ; GO:0007620 | traceable author statement male courtship behavior, tapping to detect pheromone ; GO:0016544 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 "fruitless, Dmfru, CG14307, CG7689, CT22773, CG7690, CG7688, cg7689, cg7688, BTB-VI, sat, ms(3)06411, fty, BtbVI, fru, Fru, CG14307/CG33541, FRU, fruC, FRU-PI" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR013087:Zinc finger C2H2-type" CG14307 11-Aug-17 DroID_v2017_08 Drer\hic2 - Cele\ztf-25 "Xtro\zbtb43, Xtro\zbtb34" "Mmus\Hic1, Mmus\Hic2, Mmus\Zbtb39" "Hsap\ZBTB24, Hsap\ZBTB39, Hsap\ZBTB1, Hsap\ZBTB45" " larval stage | third instar , adult stage | female , adult stage | male " " ventral nerve cord

, adult head

, central nervous system | restricted

, mushroom body

, head

, optic lobe

" "neuroanatomy defective,male limited,male,female,viable,mating behavior defective,song defective,lethal,recessive,courtship behavior defective,semi-fertile,partially lethal,partially lethal - majority live,male semi-sterile,male sterile,partially,behavior defective,mating defective,male fertile,fertile,hypoactive,chemical conditional,sterile,partially lethal - majority die,heat sensitive,lethal - all die during pupal stage,lethal - all die before end of pupal stage,some die during pupal stage,dominant,female semi-fertile,female fertile,lethal - all die before end of prepupal stage,some die during prepupal stage,conditional,size defective" "subesophageal ganglion neuron,male limited,prothoracic leg taste bristle chemosensory neuron,male,female,adult fruitless aDT-b (male) neuron,adult fruitless aSP4 neuron,adult fruitless vPR6 neuron,adult fruitless vAB3 (male) neuron,male abdominal 5 muscle,male accessory gland,vas deferens,serotonergic neuron,adult fruitless pMP-e (female) neuron,ectopic,wing,joint,anterior scutellar bristle,sternopleural bristle,tibia,macrochaeta,adult abdomen & motor neuron,adult abdomen & motor neuronfruw24),adult female posterior abdominal ganglion neuron,adult male posterior abdominal ganglion neuron,antennal lobe glomerulus DA1,antennal lobe glomerulus VA1,antennal lobe glomerulus VL2,longitudinal connective,aCC neuron,presumptive embryonic/larval central nervous system,adult fruitless aDT-b (female) neuron,adult fruitless vAB3 (female) neuron,adult fruitless vPR1 neuron,adult fruitless aSP-b (female) neuron,adult fruitless aSP-a (female) neuron,adult fruitless pIP10 neuron,adult fruitless dPR1 neuron,adult brain,dMP2 neuron,vMP2 neuron,embryonic/larval glial cell,adult fruitless aSP-b (male) neuron,adult fruitless aSP-a (male) neuron,adult brain & neuron | medial | male,eye,posterior" FBgn0027053 CSN5 COP9 signalosome subunit 5 http://flybase.org/reports/FBgn0027053 "FBgn0016027, FBgn0024551" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KRW1 NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype NEDD8-specific protease activity ; GO:0019784 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with alien axonogenesis ; GO:0007409 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype negative regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032435 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype multicellular organism development ; GO:0007275 | inferred from mutant phenotype male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype positive regulation of cell cycle ; GO:0045787 | inferred from mutant phenotype germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype positive regulation of cellular protein catabolic process ; GO:1903364 | inferred from mutant phenotype negative regulation of hemocyte proliferation ; GO:0035207 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs glial cell migration ; GO:0008347 | inferred from mutant phenotype negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | traceable author statement protein stabilization ; GO:0050821 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from mutant phenotype COP9 signalosome ; GO:0008180 | inferred from mutant phenotype nuclear periphery ; GO:0034399 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay COP9 signalosome ; GO:0008180 | inferred from direct assay COP9 signalosome ; GO:0008180 | non-traceable author statement COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity with AGI_LocusCode:At1g22920 traceable author statement "CSN5, jab1/csn5, csn5, Dch5, quo, JAB1/CSN5, Csn5, Jab1, l(3)L4032, DCH5, BcDNA.LD14392, dch5, JadBp, l(3)89Cf, l(3)M203, CH5, CG14884, BcDNA:LD14392, CSN-5, JAB1, Q9XZ58" IPR000555:JAB1/MPN/MOV34 metalloenzyme domain CG14884 11-Aug-17 DroID_v2017_08 Drer\cops5 Scer\RRI1 Cele\csn-5 Xtro\cops5 Mmus\Cops5 Hsap\COPS5 "lethal,recessive,heat sensitive,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,some die during immature adult stage,partially lethal - majority die,size defective,developmental rate defective,female sterile,germline clone,chemical sensitive,somatic clone,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,female sterile germline-dependent,wild-type" "larva,pupa,germarium,nurse cell spectrosome,germline clone,dorsal appendage,chorion | germline clone,egg,pole cell,nurse cell,trichogen cell,supernumerary,scutellum,wing,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,lamina anlage glial cell,somatic clone,ovary,photoreceptor cell R2 & axonRK6-3),photoreceptor cell R3 & axonRK6-3),photoreceptor cell R4 & axonRK6-3),photoreceptor cell R5 & axonRK6-3),melanotic mass,eye,wing vein,ectopic,cystocyte,female germline stem cell,nurse cell fusome,embryonic/larval optic neuropil" DRSC22381 K 0.719248814 0.001400095 0.895464974 0.634157517 0.303823688 1.830605397 FBgn0001228 CG4456 - http://flybase.org/reports/FBgn0001228 "FBgn0044743, FBgn0052041, FBgn0061943, FBtr0076448, FBpp0076176, FBtr0076449, FBpp0076177, FBtr0076450, FBpp0076178, FBtr0076451, FBpp0076179" protein_coding_gene - - - "hsp67B, EP(3)3247, Hspg2, gene2, gene 2, gene4, CG32041, gene-2, Hsp-G2, anon-WO0140519.138, anon-WO0118547.50, Hsp67Bb, small hsp locus 67B, hsp67Bb, CG4456" IPR001763:Rhodanese-like domain CG4456 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-165n16.1, Drer\si:dkey-34l15.1, Drer\si:ch211-161h7.8, Drer\LOC561325, Drer\si:dkey-22i16.9" "Scer\RDL1, Scer\RDL2" - "Xtro\LOC100485051, Xtro\tstd3" "Mmus\Tstd3, Mmus\Tstd1" "Hsap\TSTD1, Hsap\TSTD3" " larval stage | second instar , larval stage | third instar , adult stage | male , pupal stage | early , adult stage , spermatogenesis && adult stage , embryonic stage | >=7 hr , larval stage | first instar , pupal stage " testis

"viable,fertile" DRSC11187 I 1.590762874 0.13571716 0.238029619 0.612296906 -0.280035029 -0.352874165 FBgn0053872 His2B:CG33872 His2B:CG33872 http://flybase.org/reports/FBgn0053872 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33872, His2B:CG33872" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33872 11-Aug-17 DroID_v2017_08 "Drer\LOC100334559, Drer\si:dkey-108k21.11, Drer\si:ch211-113a14.29, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.5, Drer\LOC100329560, Drer\zgc:194989, Drer\si:ch211-113a14.28, Drer\si:ch73-368j24.8, Drer\zgc:114046, Drer\LOC100334869, Drer\si:ch73-36p18.3, Drer\zgc:173587, Drer\hist1h2ba, Drer\si:dkey-261m9.6, Drer\hist2h2l, Drer\si:ch1073-159d7.5, Drer\si:dkey-261m9.19, Drer\ano9a, Drer\si:dkey-108k21.27, Drer\si:dkey-23a13.16, Drer\zgc:92591, Drer\si:dkey-23a13.1, Drer\si:ch1073-153i20.3, Drer\si:ch1073-159d7.13, Drer\zgc:173585, Drer\LOC100329290" "Scer\HTB1, Scer\HTB2" "Cele\his-34, Cele\his-66, Cele\his-54, Cele\his-58, Cele\his-52, Cele\his-48, Cele\his-11, Cele\his-4, Cele\his-62, Cele\his-39, Cele\his-41, Cele\his-29, Cele\his-22, Cele\his-8, Cele\his-44, Cele\his-15, Cele\his-20" "Xtro\LOC100495396, Xtro\LOC100486870, Xtro\LOC100485134, Xtro\LOC100496436, Xtro\hist1h2bm, Xtro\hist1h2bk, Xtro\LOC100496181, Xtro\LOC101733489, Xtro\LOC101735164, Xtro\LOC101734494, Xtro\LOC101734862, Xtro\LOC100485294, Xtro\LOC101733828, Xtro\LOC101735218, Xtro\LOC100495578, Xtro\hist2h2be, Xtro\LOC100498329, Xtro\LOC100486150, Xtro\LOC101730940, Xtro\LOC100492632, Xtro\LOC100495415, Xtro\LOC101731067, Xtro\LOC100498647, Xtro\LOC100498553, Xtro\LOC100496445, Xtro\LOC101731852, Xtro\LOC100487485, Xtro\LOC101733171, Xtro\LOC100498072, Xtro\LOC100497082, Xtro\LOC100495041, Xtro\LOC100497915, Xtro\hist1h2bj, Xtro\LOC101731959" "Mmus\Hist3h2ba, Mmus\Hist1h2bh, Mmus\Hist1h2bq, Mmus\Hist1h2bc, Mmus\Hist1h2ba, Mmus\Hist1h2bk, Mmus\Hist1h2bj, Mmus\H2bfm, Mmus\Hist1h2bp, Mmus\Hist1h2bn, Mmus\Hist1h2bb, Mmus\Hist1h2bf, Mmus\1700024P04Rik, Mmus\Hist2h2bb, Mmus\Hist1h2br, Mmus\Hist1h2bm, Mmus\Hist1h2bg, Mmus\Hist2h2be, Mmus\Hist1h2be, Mmus\Hist1h2bl" "Hsap\HIST2H2BF, Hsap\HIST1H2BD, Hsap\HIST1H2BN, Hsap\HIST1H2BL, Hsap\HIST1H2BF, Hsap\H2BFWT, Hsap\HIST1H2BO, Hsap\HIST1H2BG, Hsap\HIST1H2BM, Hsap\HIST1H2BH, Hsap\H2BFM, Hsap\HIST1H2BK, Hsap\HIST1H2BI, Hsap\HIST1H2BJ, Hsap\HIST1H2BB, Hsap\HIST1H2BE, Hsap\HIST1H2BC, Hsap\HIST1H2BA, Hsap\HIST3H2BB, Hsap\HIST2H2BE" DRSC21265 IEK -3.316197339 -3.688847288 -3.887860139 -6.859443014 -2.278549339 -2.413391746 FBgn0015903 apt apontic http://flybase.org/reports/FBgn0015903 "FBgn0010526, FBgn0010619, FBgn0010654, FBgn0016073, FBgn0021909, FBgn0023031" protein_coding_gene "enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay mRNA binding ; GO:0003729 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with mbf1 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with bru1" "behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | traceable author statement neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype negative regulation of oskar mRNA translation ; GO:0007319 | non-traceable author statement heart development ; GO:0007507 | traceable author statement open tracheal system development ; GO:0007424 | traceable author statement central nervous system development ; GO:0007417 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay regulation of oskar mRNA translation ; GO:0046011 | inferred from genetic interaction with bru1 negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from genetic interaction with Stat92E negative regulation of oskar mRNA translation ; GO:0007319 | traceable author statement posterior head segmentation ; GO:0035289 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Apt, l(2)59Ea, CG5393, tdf, TDF/APT, TDF, l(2)06369, 3041, l(2)09049, l(2)k11531, l(2)03041, apt, Tdp" IPR028002:Myb/SANT-like DNA-binding domain CG5393 11-Aug-17 DroID_v2017_08 "Drer\atpif1b, Drer\atpif1a" - - Xtro\atpif1 Mmus\Atpif1 Hsap\ATPIF1 " embryonic stage | stage >=11 , embryonic stage | stage >=9 , embryonic stage | stage 11 , embryonic stage | cellular blastoderm , embryonic stage | 0-18 hr , embryonic stage | stage 12 , embryonic stage | stage 9-10 , adult stage && oogenesis stage , embryonic stage | stage 9-11 , embryonic stage , egg stage | unfertilized egg , embryonic stage | syncytial blastoderm , embryonic stage | stage 14-17 , embryonic stage | stage 11-17 " " embryonic/larval tracheal system

,

segmentally repeated , dorsal ridge

, tracheal primordium

, amnioserosa | vicinity of

segmentally repeated , ventral midline

segmentally repeated , dorsal vessel primordium

, labral segment

, embryonic gnathal segment | ventral

, nurse cell

, cardioblast

, tracheal pit

segmentally repeated , embryonic head

, labial segment | restricted

, oocyte

, ventral nervous system

, unfertilized egg

, follicle cell

, embryonic ocular segment | dorsal

, embryonic mandibular segment | restricted

,

ubiquitous , embryonic/larval dorsal vessel

, embryonic maxillary segment | restricted

, embryonic central nervous system

" " embryonic stage | stage >=4 , adult stage && oogenesis stage , embryonic stage | early , embryonic stage | stage 14-17 , embryonic stage | stage 11 , embryonic stage | stage >=11 " " organism

, follicle cell

, embryonic/larval tracheal system

, oocyte

, embryonic central nervous system

, nurse cell

, tracheal primordium

, embryonic/larval dorsal vessel

, embryonic head

" "lethal,chemical resistant,viable,recessive,neuroanatomy defective,fertile,visible,fully,rescuable maternal effect,tumorigenic,partially lethal - majority die,neurophysiology defective,some die during embryonic stage,cell migration defective,somatic clone,dominant,wild-type,lethal - all die before end of embryonic stage,some die during pupal stage" "anterior fascicle & synapse,synapse,intersegmental nerve,anterior fascicle & synapse | supernumerary,embryonic maxillary segment,embryonic mandibular segment,dorsocentral bristle,scutellar bristle,macrochaeta,ectopic,trichogen cell,embryonic/larval trachea,embryonic/first instar larval cuticle,embryonic head,wing,posterior compartment,embryonic/larval heart,neuromuscular junction,embryonic/larval neuromuscular junction,ventral nerve cord,egg chamber,germline clone,oocyte,central nervous system,dorsal closure embryo,presumptive embryonic/larval tracheal system,presumptive embryonic/larval central nervous system,somatic clone,border follicle cell,hypostomal sclerite,lateral process,dorsal pouch,dorsal bridge,heart primordium,egg chamber | oogenesis stage S10,border follicle cell | oogenesis stage S10,mesothoracic tergum" FBgn0261434 hkb huckebein http://flybase.org/reports/FBgn0261434 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with gro "cell fate specification ; GO:0001708 | traceable author statement glial cell differentiation ; GO:0010001 | inferred from mutant phenotype gastrulation ; GO:0007369 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | traceable author statement germ cell migration ; GO:0008354 | traceable author statement salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype inferred from genetic interaction with h transcription, DNA-templated ; GO:0006351 | non-traceable author statement salivary gland morphogenesis ; GO:0007435 | traceable author statement germ cell migration ; GO:0008354 | inferred from mutant phenotype salivary gland development ; GO:0007431 | traceable author statement endoderm formation ; GO:0001706 | traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement tube morphogenesis ; GO:0035239 | inferred from mutant phenotype ventral cord development ; GO:0007419 | traceable author statement terminal region determination ; GO:0007362 | traceable author statement central nervous system development ; GO:0007417 | inferred from genetic interaction with eg membrane organization ; GO:0061024 | traceable author statement posterior midgut invagination ; GO:0007374 | non-traceable author statement endoderm development ; GO:0007492 | inferred from mutant phenotype membrane organization ; GO:0061024 | inferred from mutant phenotype anterior/posterior axis specification ; GO:0009948 | traceable author statement ectoderm and mesoderm interaction ; GO:0007499 | non-traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "hkb, Hkb, gurt, 5953, anon-82B3, CG9768, HKB" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9768 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-221f6.1, Drer\si:ch211-191d2.2, Drer\zgc:174928" "Scer\CRZ1, Scer\YPR015C, Scer\CMR3, Scer\ZAP1" "Cele\B0310.2, Cele\pat-9, Cele\mnm-2, Cele\zag-1" "Xtro\klf17, Xtro\klf15" "Mmus\Egr1, Mmus\Zfp41" "Hsap\ZXDA, Hsap\ZXDB, Hsap\WT1, Hsap\KLF13, Hsap\KLF15, Hsap\KLF1, Hsap\SP6, Hsap\KLF14, Hsap\KLF16, Hsap\EGR1, Hsap\KLF2" " embryonic stage | stage 9-10 , embryonic stage | gastrula , embryonic stage | late , embryonic stage | stage 9-11 , embryonic stage | stage 4 , embryonic stage | stage 6-8 " " procephalic neurogenic region && embryonic ocular segment | restricted

, embryonic central nervous system | precursor | segmentally repeated pattern

, adult salivary gland primordium

posterior , tritocerebral neuroblast | subset

,

90-100% egg length , protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic intercalary segment | restricted & anterior

, deuterocerebral neuroblast | subset

, ventral neurogenic region | restricted

, organism | 0-20% egg length

,

terminal , organism | 0-10% egg length

, organism | 80-100% egg length

, adult salivary gland primordium

anterior , procephalic neurogenic region && embryonic antennal segment | restricted

" " embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | blastoderm , embryonic stage | stage 9 " " intermediate ventral neurectoderm | row 1/2

, neuroblast NB1-1

, organism | 90-100% egg length

, neuroblast NB4-2

, neuroblast NB5-4

, neuroblast NB7-3

, organism | 0-10% egg length

, neuroblast NB2-2

" FBgn0024189 sns sticks and stones http://flybase.org/reports/FBgn0024189 "FBgn0026614, FBgn0033331, FBgn0033332, FBgn0033333, FBgn0033334, FBgn0033335, FBgn0033336, FBgn0040776, FBgn0042193, FBgn0053141" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Mec2 protein binding ; GO:0005515 | inferred from physical interaction with hbs myoblast fusion ; GO:0007520 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | traceable author statement compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype nephrocyte diaphragm assembly ; GO:0036059 | inferred from mutant phenotype garland nephrocyte differentiation ; GO:0061321 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from genetic interaction with kirre nephrocyte filtration ; GO:0097206 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from direct assay spermatid development ; GO:0007286 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with EMBL:AF035385 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with EMBL:AF035385 inferred from direct assay nephrocyte diaphragm ; GO:0005917 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "sns, SNS, CG13755, CG13752, CG13753, CG8278, CG2385, CG13754, CG12495, sns20, CT33230, CT33232, rost, 43-49, CG18464, CG33141, Sns" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG33141 11-Aug-17 DroID_v2017_08 "Drer\nphs1, Drer\mybpc2b, Drer\myom1a, Drer\mybpc2a, Drer\il1rapl1b, Drer\il1rapl1a, Drer\il1rapl2, Drer\LOC799279" - "Cele\syg-2, Cele\ver-4" "Xtro\nphs1, Xtro\il1r2" "Mmus\Il1rl2, Mmus\Il1r1, Mmus\Sigirr, Mmus\Mybpc2, Mmus\Il1rapl2, Mmus\Il1r2, Mmus\Mybpc3, Mmus\Mybpc1, Mmus\Myom3, Mmus\Il18r1, Mmus\Il1rap, Mmus\Myom2, Mmus\Igfn1, Mmus\Il1rl1, Mmus\Nphs1, Mmus\Il18rap, Mmus\Il1rapl1" "Hsap\MYOM2, Hsap\IL1RL1, Hsap\IL1R1, Hsap\MYBPC2, Hsap\IL1RAPL1, Hsap\MYBPC3, Hsap\PRODH2, Hsap\IL1RL2, Hsap\MYOM3, Hsap\NPHS1, Hsap\IL1R2, Hsap\IL1RAPL2, Hsap\IL18R1, Hsap\IL1RAP, Hsap\MYBPC1, Hsap\IL18RAP, Hsap\IGFN1" " embryonic stage | stage 17 , embryonic stage | stage 11-17 , embryonic stage | stage 11-14 , embryonic stage | stage 11-13 " " muscle attachment site

, embryonic/larval somatic muscle

, somatic mesoderm

, visceral mesoderm

" " embryonic stage | stage 11-14 , embryonic stage | stage 11-17 , embryonic stage | stage 11-13 " " somatic mesoderm

, embryonic/larval somatic muscle

, visceral mesoderm

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,male fertile,lethal,cell adhesion defective,somatic clone,viable,visible,male sterile" "somatic muscle,myoblast,muscle founder cell,embryonic/larval garland cell,wing margin,wing hair,embryonic/larval pericardial cell,nephrocyte diaphragmDot.PK,presumptive embryonic/larval muscle system,A1-7 dorsal acute muscle 1,embryonic/larval muscle system,circular visceral muscle fiber,longitudinal muscle,midgut constriction 1,embryonic myoblast,embryonic/larval somatic muscle,embryonic/larval visceral muscle,circular visceral muscle primordium,embryonic garland cell,eye,somatic clone,ommatidium,inter-ommatidial cell,inter-ommatidial precursor cell,interommatidial bristle,wing,trichogen cell,mesothoracic tergum,spermatid cyst,seminal vesicle,embryonic/larval brain" DRSC07687 I -1.872664127 1.327758582 1.055115903 -0.382358116 0.664053069 -0.441701653 FBgn0000578 ena enabled http://flybase.org/reports/FBgn0000578 "FBgn0010503, FBgn0063438" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O44924 protein binding ; GO:0005515 | inferred from physical interaction with Zyx SH3 domain binding ; GO:0017124 | inferred from physical interaction with UniProtKB:P00522 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P25843 protein binding ; GO:0005515 | inferred from physical interaction with Abi SH3 domain binding ; GO:0017124 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity "regulation of cell shape ; GO:0008360 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from genetic interaction with cindr epithelial cell morphogenesis ; GO:0003382 | inferred from genetic interaction with Abl head involution ; GO:0008258 | inferred from mutant phenotype positive regulation of cell projection organization ; GO:0031346 | inferred from direct assay inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from genetic interaction with arm positive regulation of cell migration ; GO:0030335 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | traceable author statement gonad morphogenesis ; GO:0035262 | inferred from mutant phenotype subsynaptic reticulum organization ; GO:1990255 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype regulation of actin polymerization or depolymerization ; GO:0008064 | traceable author statement suture of dorsal opening ; GO:0007396 | inferred from mutant phenotype filopodium assembly ; GO:0046847 | inferred from mutant phenotype regulation of lamellipodium assembly ; GO:0010591 | inferred from mutant phenotype formation of a compartment boundary ; GO:0060288 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with robo1 germ-band shortening ; GO:0007390 | inferred from mutant phenotype regulation of filopodium assembly ; GO:0051489 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype regulation of actin cytoskeleton organization ; GO:0032956 | inferred from physical interaction with Abi" adherens junction ; GO:0005912 | inferred from direct assay lamellipodium ; GO:0030027 | inferred from direct assay subsynaptic reticulum ; GO:0071212 | inferred from direct assay cell-cell junction ; GO:0005911 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay filopodium tip ; GO:0032433 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay cell leading edge ; GO:0031252 | inferred from direct assay "Ena, CG15112, enb, ENA/VASP, Enb, l(2)02029, ena, VASP, Vasp" "IPR000697:WH1/EVH1 domain, IPR011993:PH domain-like, IPR014885:VASP tetramerisation, IPR015943:WD40/YVTN repeat-like-containing domain" CG15112 11-Aug-17 DroID_v2017_08 "Drer\evla, Drer\vaspa, Drer\enah, Drer\evlb, Drer\vaspb" - Cele\unc-34 "Xtro\enah, Xtro\evl, Xtro\vasp" "Mmus\Vasp, Mmus\Spred3, Mmus\Enah, Mmus\Evl" "Hsap\VASP, Hsap\ENAH, Hsap\EVL, Hsap\SPRED3" " embryonic stage | stage 10,11 , oogenesis stage , larval stage , embryonic stage , embryonic stage | stage 8-11 , embryonic stage | stage 12-14 , embryonic stage | stage 15,16 , embryonic stage | stage 15-17 " " endoderm

, follicle cell

, photoreceptor cell

, rhabdomere

, embryonic central nervous system | restricted

, embryonic central nervous system | presumptive

, ventral nerve cord commissure

, embryonic hindgut

, embryonic leading edge cell

, longitudinal connective

, neuron

, segment | segment boundary

, adepithelial cell

, imaginal disc | restricted

" "lethal,recessive,partially lethal - majority die,neuroanatomy defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,majority die during embryonic stage,cell shape defective,cell migration defective,size defective,viable,visible" "lamellipodium,filopodium,gonad,germline cell,gonadal sheath proper primordium,filopodium & embryonic leading edge cellen-e16E,filopodium | ectopicen-e16E,filopodiumen-e16E,border follicle cell,macrochaeta,central nervous system,commissure,stage 14 embryo,longitudinal connective,intersegmental nerve,adult mushroom body,somatic clone,embryonic/first instar larval cuticle,maternal effect,embryonic head epidermis,embryonic dorsal epidermis,actin filament & egg chamber | germ-line clone,class IV dendritic arborizing neuron,axon,peripheral nervous system,presumptive embryonic/larval central nervous system,intersegmental nerve branch ISNb of A1-7,follicle cell & actin filament | somatic clone,embryonic head,egg,germline clone,embryo,embryonic leading edge cell,ventral head epidermis,dendrite | dorsal | embryonic stage,RP neuron,follicle cell & actin filamentCY2,nurse cell & actin filamentmat.‘±Tub67C.THsimVP16,wing,NMJ bouton | third instar larval stage,subsynaptic reticulum | third instar larval stagehow-24B,embryonic/larval neuromuscular junction,NMJ bouton,trichogen cell,dorsal-ventral compartment boundary of the wing | third instar larval stage" DRSC07610 I 0.608180627 -2.102451686 -0.549969558 -0.070331999 0.301057218 1.457031514 FBgn0003944 Ubx Ultrabithorax http://flybase.org/reports/FBgn0003944 FBgn0024276 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001827 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with DIP1 RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein domain specific binding ; GO:0019904 | inferred from physical interaction with UniProtKB:P40427 DNA binding ; GO:0003677 | inferred from direct assay" "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay positive regulation of muscle organ development ; GO:0048636 | inferred from mutant phenotype muscle cell fate specification ; GO:0042694 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay anterior/posterior pattern specification ; GO:0009952 | traceable author statement mesodermal cell fate specification ; GO:0007501 | inferred from mutant phenotype haltere development ; GO:0007482 | inferred from mutant phenotype negative regulation of gene silencing ; GO:0060969 | inferred from direct assay somatic muscle development ; GO:0007525 | inferred from mutant phenotype cell fate determination ; GO:0001709 | inferred from mutant phenotype inferred from genetic interaction with Asx endoderm formation ; GO:0001706 | traceable author statement heart development ; GO:0007507 | inferred from mutant phenotype regulation of cell fate specification ; GO:0042659 | inferred from mutant phenotype specification of animal organ identity ; GO:0010092 | inferred from mutant phenotype specification of segmental identity, thorax ; GO:0007384 | inferred from mutant phenotype midgut development ; GO:0007494 | traceable author statement dorsal vessel aortic cell fate commitment ; GO:0035052 | traceable author statement anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype specification of segmental identity, thorax ; GO:0007384 | non-traceable author statement regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from expression pattern" transcription factor complex ; GO:0005667 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay "Ubx, Bxl, bxd, bx, ubx, BX-C, Cbx, Ubx1b, DmUbx, DUbx, pbx, abx, Hm, UBx, Dm Ubx, l(3)89Eb, bxl, bxd[D], bx[D], CG10388, Uab, UBX" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001827:Homeobox protein, antennapedia type, conserved site, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG10388 11-Aug-17 DroID_v2017_08 "Drer\mnx2a, Drer\hoxc8a, Drer\gbx1, Drer\hoxb6b, Drer\hoxc3a, Drer\gsx2, Drer\hoxa5a, Drer\mnx1, Drer\hoxd12a, Drer\hoxb4a, Drer\pdx1, Drer\hoxb3a, Drer\hoxa3a, Drer\hoxb1b, Drer\hoxb1a, Drer\meox2a, Drer\hoxc12a, Drer\meox2b, Drer\hoxc5a, Drer\hoxa1a, Drer\hoxa4a, Drer\nanog, Drer\hoxc4a, Drer\hoxb7a, Drer\meox1, Drer\hoxb2a, Drer\hoxd3a, Drer\gsx1, Drer\hoxa2b, Drer\hoxb8b, Drer\hoxb5a, Drer\hoxd4a, Drer\hoxa9b, Drer\hoxd11a, Drer\gbx2, Drer\hoxb5b, Drer\hoxc1a, Drer\hoxc6b, Drer\hoxc12b, Drer\hoxb6a, Drer\hoxc6a" "Scer\YHP1, Scer\PHO2, Scer\YOX1" "Cele\mab-5, Cele\lin-39" "Xtro\meox2, Xtro\hoxd1, Xtro\hoxd8, Xtro\gsx1, Xtro\hoxd3, Xtro\hoxc5, Xtro\hoxb8, Xtro\hoxa5, Xtro\hoxd10, Xtro\gbx2.2, Xtro\hoxc3, Xtro\hoxa3, Xtro\hoxc4, Xtro\gsx2, Xtro\hoxb7, Xtro\hoxb1, Xtro\hoxb4, Xtro\hoxa2, Xtro\hoxb5, Xtro\hoxb3, Xtro\hoxa1, Xtro\hoxb6, Xtro\hoxb2, Xtro\mnx1, Xtro\hoxc8, Xtro\gbx2.1, Xtro\pdx1, Xtro\tlx1" "Mmus\Hoxa5, Mmus\Hoxb1, Mmus\Hoxc6, Mmus\Hoxd8, Mmus\Gbx1, Mmus\Meox2, Mmus\Hoxd3, Mmus\Hoxc8, Mmus\Mnx1, Mmus\Hoxd1, Mmus\Hoxa7, Mmus\Hoxa4, Mmus\Hoxb3, Mmus\Hoxb7, Mmus\Hoxb4, Mmus\Hoxa6, Mmus\Gbx2, Mmus\Hoxb2, Mmus\Hoxa2, Mmus\Hoxb5, Mmus\Hoxb8, Mmus\Hoxc4, Mmus\Hoxd4, Mmus\Hoxa3, Mmus\Pdx1, Mmus\Meox1, Mmus\Hoxb6, Mmus\Hoxa1, Mmus\Gsx2, Mmus\Gsx1, Mmus\Hoxc5" "Hsap\MNX1, Hsap\HOXA2, Hsap\HOXD1, Hsap\HOXB7, Hsap\PDX1, Hsap\MEOX2, Hsap\GSX2, Hsap\GSX1, Hsap\HOXA6, Hsap\HOXA5, Hsap\HOXA4, Hsap\HOXB5, Hsap\HOXD3, Hsap\HOXA7, Hsap\HOXB3, Hsap\HOXA1, Hsap\GBX1, Hsap\HOXD4, Hsap\GBX2, Hsap\HOXC6, Hsap\HOXB2, Hsap\HOXC8, Hsap\HOXA3, Hsap\MEOX1, Hsap\HOXB8, Hsap\HOXC4, Hsap\HOXB6, Hsap\HOXB4, Hsap\HOXD8, Hsap\HOXB1, Hsap\HOXC5" " embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 1-17 , embryonic stage | stage 11-17 , embryonic stage | late " " parasegment 6 &&of embryonic central nervous system

, parasegment 5--13

, somatic mesoderm

, visceral mesoderm

, embryonic central nervous system

" " embryonic stage | mid-late , embryonic stage , embryonic stage | late , embryonic stage | stage 15-16 , larval stage , embryonic stage | stage 13-14 , embryonic stage | stage 11,13 " " parasegment 7 visceral mesoderm

{ + abd-AM1 } , visceral mesoderm &&of parasegment 7--12 <

, visceral mesoderm

{ 0 en* } , parasegment 7 visceral mesoderm

{ $ ftz* } , visceral mesoderm

{ 0 odd* } , visceral mesoderm

{ $ opa*/prd* } , visceral mesoderm

{ 0 Kr* } , visceral mesoderm

{ 0 odd*/eve* } , cardioblast && embryonic pericardial cell &&of embryonic abdominal segment 2--5

, parasegment 5--13 &&of embryonic ventral nervous system | segmentally repeated

, larval fat body | central

, visceral mesoderm

{ $ eve4 } , visceral mesoderm

, visceral mesoderm &&of embryonic/larval midgut &&ofparasegment 7

, visceral mesoderm

{ $ kni* } , visceral mesoderm

{ 0 opa* } , visceral mesoderm

{ - ftz*/prd* } , parasegment 6 visceral mesoderm

{ 0 dpphs.PT } , visceral mesoderm

{ 0 wg* } , visceral mesoderm

{ $ hb* } , visceral mesoderm

{ 0 prd* } , visceral mesoderm

{ 0 h* } , visceral mesoderm

{ - eve3 } , visceral mesoderm

{ 0 run* } , embryonic dorsal vessel | central

" "visible,dominant,homeotic,somatic clone,lethal,recessive,heat sensitive,wild-type,decreased cell size,cell autonomous,neuroanatomy defective,viable,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,fertile,reduced,partially lethal - majority die,male" "ventral thoracic disc,spiracle,embryonic dorsal vessel,abdominal ventral denticle belt,abdominal tergite 1,Kolbchen,tracheal pit,abdominal segment,haltere,metathoracic segment,Keilin's organ,wing,embryonic thoracic segment,mesothoracic tibial apical bristle,mesothoracic tibial preapical bristle,-109-68,midgut constriction,metathoracic leg,adult metathoracic segment,katepimeron,mesothoracic tergum,metathoracic metatarsus,metathoracic femur,metathoracic tarsal bristle,capitellum,haltere sensillum,dorsal metathorax,ventral metathorax,mesothoracic leg,prothoracic leg,sternopleural bristle,metathoracic tibial preapical bristle,wing margin bristle,mesothoracic intersegmental nerve,metathoracic laterotergite,adult mesothoracic segment,tracheal metamere 3,tracheal metamere 2,direct flight muscle,tergosternal muscle,coxal tergal remotor muscle,lateral oblique dorsal muscle,dorsal medial muscle,myoblast,leg,giant fiber neuron,mesothoracic extracoxal depressor muscle 66,haltere disc,mesothoracic segmental nerve,wing hair,macrochaeta,histoblast nest,embryonic head,presumptive embryonic/larval peripheral nervous system,antenna,eye,external sensory organ,abdominal 1 lateral monoscolopidial chordotonal organ lch1,mesothoracic dorsal triscolopidial chordotonal organ dch3,,prothoracic segment,mesothoracic segment,parasegment 1,parasegment 2,parasegment 3,parasegment 4,parasegment 5,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,mesothoracic femur,prothoracic femur,metathoracic tracheal pit,mesothoracic tracheal pit,head,trichome of the posterior wing margin,wing cell,wing sensillum,A-subperineurial glial cell,B-subperineurial glial cell of abdomen,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,larval head,embryonic mandibular segment,embryonic maxillary segment,embryonic labial segment,eye-antennal disc,thorax,embryonic/larval epidermis,thoracic segment,mesothoracic laterotergite,capitella sensillum trichodeum,metathoracic segmental nerve,metathoracic intersegmental nerve,embryonic epidermis,alula,aorta primordium,wing disc,abdominal ventral acute muscle,embryonic/larval lymph gland,embryonic visceral muscle,embryonic anterior Malpighian tubule,multidendritic neuron,adult prothoracic segment,posterior vertical bristle,postvertical bristle,chordotonal organ,abdominal dorsal transverse muscle,abdominal 1 lateral transverse muscle,abdominal 2 lateral transverse muscle,presumptive embryonic/larval central nervous system,metathoracic pleurum,mesothoracic pleurum,embryonic head segment,T1 beard,gastric caecum,dorsal acute muscle,scutum,embryonic/first instar larval cuticle,indirect flight muscle,mesothoracic dorsal acute muscle 3,metathoracic dorsal acute muscle,cardioblast,embryonic/larval ostia,embryonic/larval dorsal vessel,gonadal sheath proper primordium,larval neuromere,arista,pretarsus,embryonic tritocerebrum,adult head,embryonic/larval pericardial cell,eye disc,lymph gland primordium,embryonic/larval posterior spiracle,abdominal 11 anal tuft,wing blade,wing margin,cephalopharyngeal skeleton,pharynx,prothoracic ventral intersegmental muscle,T1 beard,dorsal closure embryo,embryonic brain,ppk.PG,skeletal muscle of thorax" FBgn0003513 ss spineless http://flybase.org/reports/FBgn0003513 - protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with tgo transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from direct assay" specification of animal organ identity ; GO:0010092 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype antennal development ; GO:0007469 | inferred from expression pattern male courtship behavior ; GO:0008049 | inferred from mutant phenotype regulation of R7 cell differentiation ; GO:0045676 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype response to xenobiotic stimulus ; GO:0009410 | inferred from biological aspect of ancestor with PANTHER:PTN000837813 regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000837813 cytosol ; GO:0005829 | inferred from direct assay nuclear aryl hydrocarbon receptor complex ; GO:0034753 | inferred from biological aspect of ancestor with PANTHER:PTN000837813 nucleus ; GO:0005634 | inferred from direct assay "AHR, SS, ssa, Ss, CG6993, ss, AhR" "IPR000014:PAS domain, IPR001610:PAC motif, IPR013655:PAS fold-3, IPR013767:PAS fold, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG6993 11-Aug-17 DroID_v2017_08 "Drer\ahr1a, Drer\ahrrb, Drer\ahr1b, Drer\ahr2" - Cele\ahr-1 "Xtro\ahr, Xtro\arnt" "Mmus\Ahrr, Mmus\Ahr" "Hsap\PDCD6, Hsap\AHRR, Hsap\AHR" " embryonic stage | stage >8 , pupal stage , embryonic stage , larval stage | third instar , larval stage | second instar , embryonic stage | stage 8 " " embryonic labial segment

, sensory mother cell

, embryonic antennal segment

, trichogen cell

, dorsal metathoracic disc

, tarsus | presumptive

, eye disc

, antennal disc

, leg | anlagen

, dorsal mesothoracic disc | restricted

, labial disc

, embryonic mandibular segment

, embryonic maxillary segment

, embryonic peripheral nervous system

, cephalic furrow | anterior to

, genital disc

, morphogenetic furrow

, ventral thoracic disc

, maxillary palpus | anlagen

" "visible,homeotic,viable,fertile,somatic clone,recessive,lethal,gravitaxis defective,reduced,sterile,dominant,flightless,courtship behavior defective,memory defective,male sterile,female semi-sterile,neuroanatomy defective,behavior defective,increased cell death,cell non-autonomous,cell autonomous,heat sensitive" "dorsomedial papilla,dendrite & dorsal multidendritic neuron ddaE,macrochaeta,tarsal segment,labial sensillum,somatic clone,bract,arista,proximal,third segment of antenna,distal,antenna,antennal segment,sex comb,ectopic,joint,metatarsus,second segment of antenna,fourth segment of antenna,fifth segment of antenna,antennal disc,leg,tarsal segment 2,tarsal segment 3,tarsal segment 4,ventral thoracic disc,pretarsus,microchaeta,wing,mesothoracic tarsal segment,vertical bristle,posterior vertical bristle,scutellar bristle,prothoracic tarsal segment,metathoracic tarsal segment,unguis,cold sensitive,maxillary palpus,antennal sense organ,dendrite & dorsal multidendritic neuron ddaE | somatic clone,dendrite & dorsal multidendritic neuron ddaD | somatic clone,dendrite & dorsal multidendritic neuron ddaB | somatic clone,dendrite & dorsal multidendritic neuron ddaC | somatic clone,dendrite & lateral multidendritic neuron ldaB | somatic clone,dendrite & dorsal multidendritic neuron ddaF | somatic clone,pale ommatidium,yellow ommatidium,photoreceptor cell R7 of yellow ommatidium,photoreceptor cell R7 of pale ommatidium,eye-antennal disc,chaeta,thorax,mesothoracic leg,denticle belt,medial,tracheal branch primordium,rostral membrane,femur,anterior compartment,tibia,tergite,wing margin,wing disc,cell autonomous,dendrite & tracheal innervating neuron477,dendrite & dorsal multidendritic neuron ddaCppk.PG,eye,ommatidium,eye photoreceptor cell,heat sensitive,trichogen cell,mesothoracic tergum" FBgn0005672 spi spitz http://flybase.org/reports/FBgn0005672 "FBgn0002048, FBgn0003474, FBgn0010472, FBgn0010690, FBgn0062206" protein_coding_gene epidermal growth factor receptor binding ; GO:0005154 | traceable author statement epidermal growth factor receptor binding ; GO:0005154 | non-traceable author statement "negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype G2/M transition of mitotic cell cycle ; GO:0000086 | non-traceable author statement epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | non-traceable author statement R8 cell-mediated photoreceptor organization ; GO:0045470 | non-traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | non-traceable author statement branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | non-traceable author statement salivary gland boundary specification ; GO:0007432 | non-traceable author statement open tracheal system development ; GO:0007424 | traceable author statement epithelial cell proliferation involved in Malpighian tubule morphogenesis ; GO:0061331 | inferred from mutant phenotype stem cell fate commitment ; GO:0048865 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement positive regulation of neurogenesis ; GO:0050769 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype heart process ; GO:0003015 | inferred from mutant phenotype positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | non-traceable author statement oenocyte development ; GO:0007438 | inferred from mutant phenotype inferred from genetic interaction with abd-A neurogenesis ; GO:0022008 | inferred from mutant phenotype stomatogastric nervous system development ; GO:0007421 | inferred from mutant phenotype determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype" Golgi apparatus ; GO:0005794 | inferred from genetic interaction with S extracellular region ; GO:0005576 | traceable author statement endoplasmic reticulum ; GO:0005783 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement integral component of membrane ; GO:0016021 | non-traceable author statement endoplasmic reticulum ; GO:0005783 | non-traceable author statement "spi, CG10334, EP(2)2378, CT29014, Spitz, l(2)01068, Spi, l(2)s3547, l(2)37Fa, anon-WO0118547.158, s-spi, sSpi" "IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site" CG10334 11-Aug-17 DroID_v2017_08 - - - - Mmus\Tradd Hsap\TRADD embryonic stage " peripheral nervous system

, ventral midline

, mesoderm

" embryonic stage " ventral midline

, mesoderm

" "viable,fertile,neuroanatomy defective,poor,visible,recessive,lethal,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,learning defective,RU486 conditional,heat sensitive,wild-type,increased cell death,somatic clone,cell death defective,increased cell number,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,lethal - all die before end of pupal stage,some die during pupal stage,homeotic,male,female,decreased cell number,chemical resistant" "anterior commissure,posterior commissure,midline glial cell,,ventral oblique muscle,embryonic/larval somatic muscle,ventral longitudinal muscle,abdominal dorsal acute muscle,optic lobe,Bolwig organ,embryonic stomatogastric nervous system,embryonic/larval brain,hypocerebral ganglion,embryonic/larval recurrent nerve,epidermis,peripheral nervous system,eye,rhabdomere,egg,photoreceptor,macrochaeta,ventral nerve cord,embryonic/larval ganglionic branch,embryonic/first instar larval cuticle,wing,embryonic/larval salivary gland,intersegmental nerve,midgut,bract,lamellocyte,photoreceptor cell,cone cell,pigment cell,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron,abdominal ventral monoscolopidial chordotonal organ,abdominal lateral pentascolopidial chordotonal organ,embryonic ventral nervous system,Keilin's organ,anal pad,cephalopharyngeal skeleton,Malpighian tubule,embryonic anterior Malpighian tubule,genital disc primordium,tracheal primordium,presumptive embryonic/larval tracheal system,embryonic/larval stomatogastric nervous system,stomodeal invagination,lch5 cap attachment cell,lch5 ligament attachment cell,embryonic/larval trachea,A1-7 ventral acute muscle 2,embryonic ventral epidermis,eye disc,embryonic/larval oenocyte,midline ventral glial cell,ventral nerve cord commissure,ommatidium,dorsal neurohemal organ,embryonic/larval optic lobe,peripheral glial cell,anterior fascicle sensory neuron,posterior fascicle sensory neuron,adult salivary gland primordium,embryonic segment,lch5 neuron,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,germline stem cell,embryonic epidermis,wing disc,en-e16E,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic prothoracic segment,stigmatophore,filzkorper,trichome,neuron,hs.PB,retina,subretinal glial cell,denticle,embryonic/larval cuticle,dorsal appendage,dorsal hair,muscle founder cell |,ventral thoracic disc,mesothoracic tibial apical bristle,prothoracic tibial apical bristle,Dll-md23,antenna,wing hair,aCC neuron,pCC neuron,mesothoracic tibial bract,border follicle cell,stomatogastric nervous system anlage,adult midgut precursor cell |,midgut interstitial cell,lamellocyte | larval stage,enterocyte,chorion,ganglion mother cell,embryonic/larval brain,adult heart" DRSC03618 E -0.281165558 0.118014637 -2.175545547 -0.08601617 0.128460281 -0.762398571 FBgn0004102 oc ocelliless http://flybase.org/reports/FBgn0004102 "FBgn0002979, FBgn0003021" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Gsc protein homodimerization activity ; GO:0042803 | inferred from physical interaction with oc" "embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype nervous system development ; GO:0007399 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype photoreceptor cell fate commitment ; GO:0046552 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | traceable author statement ocellus morphogenesis ; GO:0048816 | non-traceable author statement ocellus development ; GO:0008056 | inferred from genetic interaction with toy anterior region determination ; GO:0007355 | traceable author statement compound eye photoreceptor development ; GO:0042051 | traceable author statement brain development ; GO:0007420 | non-traceable author statement compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype negative regulation of rhodopsin gene expression ; GO:0045871 | inferred from mutant phenotype pattern specification process ; GO:0007389 | non-traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay positive regulation of compound eye photoreceptor development ; GO:0045315 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype anterior head segmentation ; GO:0035288 | traceable author statement brain segmentation ; GO:0035284 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay brain development ; GO:0007420 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype rhabdomere morphogenesis ; GO:0061541 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype ocellus photoreceptor cell development ; GO:0042463 | inferred from genetic interaction with Pph13 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype positive regulation of rhodopsin gene expression ; GO:0045872 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0001077 "otd, Otx, Otd, uvi, ort, l(1)8Ac, l(1)7Ff, CG12154, oc, Oc, ocelliless, orthodenticle" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG12154 11-Aug-17 DroID_v2017_08 "Drer\otx5, Drer\otx1a, Drer\crx, Drer\otx2, Drer\otx1b" - "Cele\ceh-37, Cele\ceh-54, Cele\ttx-1, Cele\ceh-36" "Xtro\otx2, Xtro\otx1, Xtro\crx" "Mmus\Rhox12, Mmus\Vax2, Mmus\Crx, Mmus\Otx2, Mmus\Obox5, Mmus\Obox7, Mmus\Vax1, Mmus\Otx1, Mmus\Obox3, Mmus\Obox6, Mmus\Obox1" "Hsap\DPRX, Hsap\VAX2, Hsap\LEUTX, Hsap\OTX2, Hsap\ARGFX, Hsap\OTX1, Hsap\VAX1, Hsap\CRX" " embryonic stage | 5-13 hr , embryonic stage | cellular blastoderm , embryonic stage | stage 5 , embryonic stage | stage 3 , embryonic stage | stage 3-5 , embryonic stage | stage 7 , embryonic stage | stage 4 , embryonic stage | stage 6-17 , embryonic stage | stage 8 , embryonic stage " " ventral midline

,

70-90% egg length , organism | 80-100% egg length

,organism | dorsal

,

anterior , procephalic segment

, organism | 70-90% egg length

, procephalic neurogenic region | restricted

, organism | 90-100% egg length

, head mesoderm

, head

" embryonic stage | stage 9-11 " procephalic neurogenic region && embryonic intercalary segment | restricted & ventral

, tritocerebral neuroblast | subset

, procephalic neurogenic region &&of embryonic ocular segment

, protocerebral neuroblast | subset

, deuterocerebral neuroblast | subset

, procephalic neurogenic region && embryonic head | restricted & dorsal & central

, procephalic neurogenic region && embryonic antennal segment

" "visible,viable,female sterile,lethal,recessive,locomotor behavior defective,eclosion rhythm defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,visual behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic head,embryonic segment,ganglion,ectopic,presumptive embryonic/larval central nervous system,embryonic brain,embryonic head & ganglion,ventral nerve cord,posterior,presumptive embryonic/larval peripheral nervous system,dorsomedial papilla,antennal sense organ,dorsolateral papilla,terminal organ,cephalopharyngeal skeleton,cirri,ocellus & macrochaeta,frons & macrochaeta,macrochaeta,ocellus,frons,female accessory gland,protocerebral bridge,postvertical bristle,ocellar bristle,interocellar bristle,lateral ocellus,medial ocellus,ocellus pigment granule,ocellus lens,protocerebral neuromere,embryonic protocerebral neuromere,embryonic brain & commissure,neuropil,commissure,embryonic ventral epidermis,longitudinal connective,embryonic antennal segment,posterior commissure,antennal primordium,antennal segment,growth cone,anterior commissure,midline glial cell,abdominal 1 dorsal VUM motor neuron,abdominal 2 dorsal VUM motor neuron,abdominal 3 dorsal VUM motor neuron,abdominal 4 dorsal VUM motor neuron,abdominal 5 dorsal VUM motor neuron,abdominal 6 dorsal VUM motor neuron,abdominal 7 dorsal VUM motor neuron,abdominal 1 ventral VUM motor neuron,abdominal 2 ventral VUM motor neuron,abdominal 3 ventral VUM motor neuron,abdominal 4 ventral VUM motor neuron,abdominal 5 ventral VUM motor neuron,abdominal 6 ventral VUM motor neuron,abdominal 7 ventral VUM motor neuron,abdominal 1 lateral VUM motor neuron,abdominal 2 lateral VUM motor neuron,abdominal 3 lateral VUM motor neuron,abdominal 4 lateral VUM motor neuron,abdominal 5 lateral VUM motor neuron,abdominal 6 lateral VUM motor neuron,abdominal 7 lateral VUM motor neuron,neuroblast MNB,deuterocerebral neuromere,ventral midline,abdominal neuromere,embryonic protocerebrum,embryonic central brain,pars intercerebralis,protocerebrum,female gonopod,denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,photoreceptor cell,rhabdomere,cone cell,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere R7,rhabdomere R8,rhabdomere of eye photoreceptor cell,ommatidium,photoreceptor,rhabdomereoc.1.6,embryonic/larval pharynx | embryonic stage,mouth hooks,precursor cell of the stomatogastric nervous system" FBgn0028325 l(1)G0334 lethal (1) G0334 http://flybase.org/reports/FBgn0028325 protein_coding_gene pyruvate dehydrogenase (acetyl-transferring) activity ; GO:0004739 | inferred from sequence or structural similarity with UniProt:P29803 inferred from sequence or structural similarity with UniProtKB:P08559 acetyl-CoA biosynthetic process from pyruvate ; GO:0006086 | inferred from electronic annotation with InterPro:IPR017597 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:P29803 mitochondrion ; GO:0005739 | inferred from direct assay pyruvate dehydrogenase complex ; GO:0045254 | inferred from sequence or structural similarity with UniProt:P29803 inferred from sequence or structural similarity with UniProtKB:P08559 "CG7010, l(1)G0334, E1-PDH, L(1)g0334, l (1) G0334, CG 7010, PDH, Pdh, L(1)G0334, PDHE1, pdha" "IPR001017:Dehydrogenase, E1 component, IPR017597:Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y, IPR029061:Thiamin diphosphate-binding fold" CG7010 11-Aug-17 DroID_v2017_08 "Drer\pdha1a, Drer\pdha1b" Scer\PDA1 Cele\pdha-1 Xtro\pdha1 "Mmus\Pdha2, Mmus\Pdha1" "Hsap\PDHA1, Hsap\PDHA2" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable" FBgn0283451 br broad http://flybase.org/reports/FBgn0283451 protein_coding_gene "RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "metamorphosis ; GO:0007552 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of development, heterochronic ; GO:0040034 | traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement progression of morphogenetic furrow involved in compound eye morphogenesis ; GO:0007458 | inferred from mutant phenotype compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype regulation of development, heterochronic ; GO:0040034 | inferred from mutant phenotype male genitalia morphogenesis ; GO:0048808 | inferred from mutant phenotype response to ecdysone ; GO:0035075 | inferred from mutant phenotype eclosion ; GO:0007562 | inferred from expression pattern autophagy ; GO:0006914 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cell death ; GO:0008219 | traceable author statement response to symbiont ; GO:0009608 | inferred from mutant phenotype muscle fiber development ; GO:0048747 | inferred from genetic interaction with twi inferred from genetic interaction with Mef2 oogenesis ; GO:0048477 | inferred from mutant phenotype cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from direct assay "Z4, br, CG11491, BR-C, BrC, rbp, BR_C, BR-C Z1, br-Z1, br-Z3, BR, 2Bc, nrp, npr, PP1, BRC, BR-c, BrC-Z1, br-C, EG:25D2.1, EG:17A9.1, EG:123F11.1, l(1)G0284a, Br-C, CG11514, CG11511, BRC-Z1, 2B5, npr1, ecs, nprl, l(1)2Bc, l(1)2Bab, Z3, Z2, Z1, l(1)PP1, uq, l(1)npr1, rds, l(1)ESHS5, l(1)2Bd, A18, l(1)npr-1, npr-1, de12, l(1)d norm-12, l(1)pp-2, l(1)pp-1, PP2, l(1)pp1, l(1)pp2, l(1)G0018, l(1)G0042, l(1)G0401, l(1)G0318, rdp, o.c.c., l(1)ts376, l(1)ts358, l(1)ts144, l(1)ts132, l(1)n34, l(1)dn1, l(1)d.norm.1, l(1)2Bb, l(1)2Bad, l(1)2Ba, l(1)G0284, Br, BRC-Z2, BRC-Z3, BRC-Z4, Br-C Z2, Br-C-Z3, nrp1, Br-Z4, BrZ3, CG11509, br-Z2, br-Z4, BR-Z1, BR-Z2, BR-Z3, BR-Z4, Br-Z2" "IPR011990:Tetratricopeptide-like helical domain, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG11491 11-Aug-17 DroID_v2017_08 - - - - - "Hsap\ZBTB41, Hsap\ZBTB14, Hsap\ZBTB49, Hsap\MYNN, Hsap\ZBTB24, Hsap\ZBTB39" "viable,lethal,some die during pupal stage,neuroanatomy defective,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage,gravitaxis defective,lethal - all die before end of pupal stage,female fertile,male fertile,visible,heat sensitive,developmental rate defective,female sterile,chemical resistant,long lived,male,Minute,immune response defective,somatic clone,partially,body color defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,wild-type,eye color defective,fertile,flightless,decreased cell death,reduced,female,cold sensitive,lethal - all die before end of P-stage,some die during pharate adult stage,maternal effect,partially lethal - majority die,good,locomotor behavior defective,some die during third instar larval stage" "dorsal multidendritic neuron ddaC,polytene chromosome puff,dorsal appendage,embryonic/larval hemocyte | third instar larval stage,pupa,leg,optic lobe,adult brain,wing,maxillary palpus,maxillary palpus & macrochaeta,rostral membrane,ovary,embryonic/larval salivary gland,embryonic/larval proventriculus,indirect flight muscle,endochorion,chorion,egg operculum,somatic clone,wing margin & sensory neuron | somatic clone,chemosensory ventral triple row bristle,imaginal disc,ommatidium,morphogenetic furrow,photoreceptor cell,supernumerary,photoreceptor cell R8,eye,embryonic/larval central nervous system,maxillary palp bristle,ectopic,cold sensitive,male genitalia,chaeta,heat sensitive,socket,adult cuticle,microchaeta,macrochaeta,head bristle,mesothoracic bristle,metathoracic bristle,adult abdominal sensillum,abdominal dorsal trichome,tergite,follicle cell,ovary & nucleus | conditional cs,micropyle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,dorsal medial muscle,mesothoracic extracoxal depressor muscle 66,pigment cell,abdomen,scutellar bristle,medulla,lobula plate,Malpighian tubule,yellow body,metathoracic tarsal segment,metathoracic leg,adult head,egg,germline clone,muscle tendon junction & coxal tergal remotor muscle,muscle tendon junction & tergosternal muscle,muscle tendon junction & lateral oblique dorsal muscle,tendon cell,thorax,adult epidermis,salivary gland,abdominal sternite bristle,embryonic/larval somatic muscle,ring gland,microchaeta & thorax,microchaeta & adult thorax,embryonic/larval esophagus,lobula,embryonic/larval midgut,ventral thoracic disc,puparium,sensory neuron & dorsal mesothoracic discbbg-C96,wing margin & sensory neuronbbg-C96,prothoracic gland,LNv neuron,trichogen cell,mesothoracic tergum" DRSC17788 IE 1.510314494 0.858648982 2.957708144 -0.579072964 -0.053337797 -1.485471636 FBgn0051481 pb proboscipedia http://flybase.org/reports/FBgn0051481 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001827 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001827, InterPro:IPR017970 specification of segmental identity, labial segment ; GO:0007381 | inferred from mutant phenotype specification of segmental identity, maxillary segment ; GO:0007382 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype proboscis development ; GO:0048728 | inferred from mutant phenotype specification of segmental identity, maxillary segment ; GO:0007382 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "pb, PB, l(3)04498, pd, CG17880, CG31481, BG:DS01719.1, Pb, pr, Dmpb" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001827:Homeobox protein, antennapedia type, conserved site, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG31481 11-Aug-17 DroID_v2017_08 "Drer\hoxb4a, Drer\hoxc3a, Drer\hoxb2a, Drer\mnx1, Drer\pdx1, Drer\hoxb3a, Drer\hoxb1b, Drer\hoxa2b, Drer\hoxb6b, Drer\meox1, Drer\hoxa9b, Drer\hoxc1a, Drer\hoxd4a, Drer\hoxd3a, Drer\gbx2, Drer\gbx1, Drer\hoxa3a, Drer\hoxb5b, Drer\hoxc5a, Drer\hoxb8b, Drer\hoxa5a, Drer\meox2a, Drer\hoxc4a, Drer\mnx2a, Drer\hoxb7a, Drer\gsx2, Drer\hoxa4a, Drer\hoxc6b, Drer\hoxc6a, Drer\meox2b, Drer\hoxa1a, Drer\hoxc8a, Drer\hoxb1a, Drer\hoxb6a, Drer\hoxb5a, Drer\gsx1" "Scer\YHP1, Scer\YOX1, Scer\PHO2" "Cele\Y39B6A.1, Cele\ceh-43" "Xtro\mnx1, Xtro\hoxc3, Xtro\hoxc5, Xtro\hoxa3, Xtro\hoxb3, Xtro\meox2, Xtro\hoxd1, Xtro\hoxb2, Xtro\gbx2.1, Xtro\gbx2.2, Xtro\hoxa5, Xtro\hoxa1, Xtro\hoxb6, Xtro\hoxc8, Xtro\hoxb5, Xtro\nkx2-3, Xtro\hoxa2, Xtro\hoxd8, Xtro\gsx2, Xtro\hoxb1, Xtro\hoxc4, Xtro\hoxd3, Xtro\hoxb7, Xtro\gsx1, Xtro\hoxb4, Xtro\pdx1, Xtro\hoxb8" "Mmus\Gsx1, Mmus\Hoxc8, Mmus\Hoxa6, Mmus\Hoxd1, Mmus\Hoxa1, Mmus\Hoxa3, Mmus\Hoxb6, Mmus\Gbx1, Mmus\Hoxa7, Mmus\Gsx2, Mmus\Hoxc6, Mmus\Gbx2, Mmus\Hoxb3, Mmus\Hoxc5, Mmus\Hoxb2, Mmus\Hoxd4, Mmus\Hoxd8, Mmus\Hoxc4, Mmus\Meox1, Mmus\Hoxb5, Mmus\Hoxb4, Mmus\Hoxd3, Mmus\Pdx1, Mmus\Mnx1, Mmus\Hoxa4, Mmus\Hoxb1, Mmus\Hoxb7, Mmus\Meox2, Mmus\Hoxb8, Mmus\Hoxa5, Mmus\Hoxa2" "Hsap\GBX2, Hsap\MEOX2, Hsap\HOXC5, Hsap\GSX2, Hsap\HOXA6, Hsap\HOXA7, Hsap\HOXA2, Hsap\HOXA5, Hsap\HOXC6, Hsap\HOXB2, Hsap\HOXB7, Hsap\HOXB3, Hsap\HOXA4, Hsap\HOXD4, Hsap\GBX1, Hsap\HOXB8, Hsap\HOXA1, Hsap\MNX1, Hsap\GSX1, Hsap\HOXB1, Hsap\MEOX1, Hsap\HOXC8, Hsap\HOXB5, Hsap\HOXA3, Hsap\PDX1, Hsap\HOXD3, Hsap\HOXB6, Hsap\HOXB4, Hsap\HOXD8, Hsap\HOXC4, Hsap\HOXD1" embryonic stage&&larval stage&&pupal stage " embryonic stage | 6hr , embryonic stage " " stomodeum | posterior to

, embryonic/larval foregut

, embryonic central nervous system | restricted

, embryonic mandibular segment

, subesophageal ganglion

, mesoderm | presumptive

, mesothoracic segment &&of ventral nerve cord

, prothoracic segment | posterior ventral nerve cord

, metathoracic segment &&of ventral nerve cord

, embryonic labial segment

, supraesophageal ganglion

, embryonic maxillary segment

" "visible,recessive,lethal,heat sensitive,dominant,wild-type,male,female,homeotic,somatic clone,temperature conditional,lethal - all die before end of pupal stage,some die during pupal stage" "labellum,distal,maxillary palpus,labellar cap,pseudotrachea,arista,ectopic,heat sensitive,tarsal segment & mouthpart | conditional ts, with pb27/pb20,sex comb,sex comb & prothoracic leg | conditional ts,prothoracic leg,prothoracic tarsal segment,leg,tarsal segment,embryonic head,tarsal segment & mouthpart | conditional ts, with pb20, pb27,T1 beard,extended germ band embryo,larval head,mesothoracic tarsal segment,metathoracic tarsal segment,antenna,prothoracic leg & sex comb,third segment of antenna,second segment of antenna,head,posterior vertical bristle,eye,anterior,dorsal row,ventral row,microchaeta & wing,wing sensillum,wing vein L3 & macrochaeta,macrochaeta,fourth segment of antenna,wing vein L3,ventral,ommatidium,interommatidial bristle,posterior,wing,labial disc,antennal sense organ,tarsal segment & mouthpart,proboscis,macrochaeta & prementum,labial segment,somatic clone,unguis,pulvillus,tarsal segment & mouthpart | conditional ts, with pbQ50K.hs,tarsal segment & mouthpart | conditional ts, with pb27, pbQ50K.hs,temperature conditional,proboscis & sex comb | ectopic,tarsal segment & mouthpart | conditional ts, with pb20, pbQ50K.hs,wing & macrochaetadpp.blk1,wing vein,crossvein,imaginal disc,wing margin,embryonic tritocerebrum,prothoracic ventral intersegmental muscle,mesothoracic ventral oblique muscle 2,metathoracic ventral acute muscle,visceral mesoderm,midgut chamber 1,gastric caecum primordium" FBgn0003015 osk oskar http://flybase.org/reports/FBgn0003015 - protein_coding_gene - "pole plasm assembly ; GO:0007315 | traceable author statement pole plasm protein localization ; GO:0007318 | traceable author statement visual learning ; GO:0008542 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of mRNA stability ; GO:0043488 | inferred from mutant phenotype P granule organization ; GO:0030719 | inferred from mutant phenotype pole cell formation ; GO:0007279 | traceable author statement long-term memory ; GO:0007616 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | non-traceable author statement long-term memory ; GO:0007616 | traceable author statement P granule organization ; GO:0030719 | traceable author statement pole plasm mRNA localization ; GO:0019094 | traceable author statement germ cell development ; GO:0007281 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | non-traceable author statement regulation of oskar mRNA translation ; GO:0046011 | traceable author statement thermosensory behavior ; GO:0040040 | inferred from mutant phenotype posterior abdomen determination ; GO:0007359 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype" P granule ; GO:0043186 | inferred from direct assay P granule ; GO:0043186 | traceable author statement cell cortex ; GO:0005938 | inferred from direct assay pole plasm ; GO:0045495 | traceable author statement pole plasm ; GO:0045495 | "Osk, osk, CG10901, Oskar, OSK, Dm-osk, norka, oskar" "IPR013830:SGNH hydrolase-type esterase domain, IPR025605:OST-HTH/LOTUS domain, IPR033447:OSK domain" CG10901 11-Aug-17 DroID_v2017_08 - - - - - - " oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage >S8 , embryonic stage | early , adult stage && oogenesis stage | stage >S10 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-7 , oogenesis stage " " germarium region 2b

, oocyte | dorsal <&> anterior

,

posterior , oocyte

, oocyte | posterior

, nurse cell

" " embryonic stage | early , adult stage && oogenesis stage | stage S10 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S9 " " pole granule

, oocyte | posterior

, egg chamber | posterior

" "lethal,maternal effect,recessive,visible,memory defective,learning defective,visual behavior defective,neurophysiology defective,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,wild-type,female sterile,dominant,decreased cell number,grandchildless,sterile,viable,increased cell death,male sterile,meiotic cell cycle defective,heat sensitive" "germline cell,embryonic head,pole cell,pole plasm,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,germinal proliferation center hub,embryo,germline clone,maternal effect,posterior,embryonic thorax,embryonic abdomen,embryonic epidermis,abdomen,ectopic,supernumerary,anterior,prothoracic ventral denticle belt,presumptive embryonic/larval muscle system,embryonic myoblast,cephalopharyngeal skeleton,microtubule & oocyte | oogenesis stage S9p-XT103),embryonic/first instar larval cuticle,denticle belt,pole granule,egg chamber,karyosome,oocyte,mouth hooks,prothoracic segment,gonad,germline stem cell,heat sensitive,embryonic/first instar larval cuticle & embryonic headnos.UTR.THsimVP16,extended germ band embryo,embryonic telson,embryonic/larval foregut,embryonic/larval hindgut,microtubule & oocyte | oogenesis stage S9mat.‘±Tub67C.THsimVP16,trichogen cell,filamentous actin & oocytemat.‘±Tub67C.THsimVP16" FBgn0051103 CG31103 - http://flybase.org/reports/FBgn0051103 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701" integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 "CG13655, CG31103" "IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG31103 11-Aug-17 DroID_v2017_08 "Drer\sv2a, Drer\svopb, Drer\LOC101884074, Drer\slc22a5, Drer\sv2bb, Drer\svopl, Drer\sv2, Drer\LOC100334012, Drer\sv2c, Drer\zgc:175176, Drer\slc22a7b.2, Drer\svopa, Drer\slc22a7b.3, Drer\oatx, Drer\slc22a6l, Drer\slc22a21, Drer\slc22a13, Drer\sv2ba, Drer\zmp:0000001102, Drer\slc22a7b.1" "Scer\GAL2, Scer\QDR1, Scer\QDR2, Scer\TPO3, Scer\FLR1, Scer\YHK8, Scer\QDR3, Scer\TPO1, Scer\TPO2, Scer\DTR1, Scer\AQR1" "Cele\oat-1, Cele\svop-1" "Xtro\slc22a6, Xtro\sv2b" "Mmus\Svop, Mmus\Slc22a22, Mmus\Sv2a, Mmus\Svopl, Mmus\Sv2b, Mmus\Slc22a16, Mmus\Slc22a19, Mmus\Slc22a28, Mmus\Slc22a26, Mmus\Slc22a29, Mmus\Slc22a14, Mmus\Slc22a4, Mmus\Slc22a2, Mmus\Sv2c, Mmus\Slc22a27, Mmus\Slc22a20, Mmus\Slc22a7, Mmus\Slc22a8, Mmus\Slc22a30, Mmus\Slc22a23, Mmus\Slc22a6" "Hsap\SV2C, Hsap\SLC22A2, Hsap\SLC22A23, Hsap\SLC22A1, Hsap\SLC22A12, Hsap\SLC22A24, Hsap\SV2A, Hsap\SLC22A10, Hsap\SLC22A7, Hsap\SLC22A8, Hsap\SV2B, Hsap\SVOPL, Hsap\SLC22A9, Hsap\SLC22A11, Hsap\SLC22A25, Hsap\SVOP, Hsap\SLC22A6" viable FBgn0027217 l(1)G0324 lethal (1) G0324 http://flybase.org/reports/FBgn0027217 - gene - - - l(1)G0324 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0000183 BicD Bicaudal D http://flybase.org/reports/FBgn0000183 FBgn0025237 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2 inferred from physical interaction with Rab39 inferred from physical interaction with Rab30 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab30 mRNA binding ; GO:0003729 | NOT non-traceable author statement clathrin heavy chain binding ; GO:0032050 | inferred from physical interaction with Chc protein binding ; GO:0005515 | inferred from physical interaction with Rab6 dynein complex binding ; GO:0070840 | non-traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from genetic interaction with EndoA germarium-derived oocyte fate determination ; GO:0007294 | traceable author statement oocyte microtubule cytoskeleton organization ; GO:0016325 | traceable author statement positive regulation of synaptic vesicle exocytosis ; GO:2000302 | inferred from mutant phenotype positive regulation of clathrin-dependent endocytosis ; GO:2000370 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | traceable author statement mRNA transport ; GO:0051028 | inferred from mutant phenotype oocyte axis specification ; GO:0007309 | traceable author statement oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype oocyte nucleus migration involved in oocyte dorsal/ventral axis specification ; GO:0007312 | traceable author statement germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype cellular macromolecule localization ; GO:0070727 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement RNA transport ; GO:0050658 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype mRNA transport ; GO:0051028 | inferred from direct assay germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from electronic annotation with InterPro:IPR018477 cytosol ; GO:0005829 | inferred from direct assay clathrin-coated endocytic vesicle membrane ; GO:0030669 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "BicD, Bic-D, BIC-D, Bic[D], anon-EST:fe2A11, CG6605, BICD, almond" "IPR018477:Bicaudal-D protein, microtubule-associated" CG6605 11-Aug-17 DroID_v2017_08 "Drer\bicd2, Drer\zgc:162200, Drer\zgc:171572, Drer\bicd1a" Scer\USO1 Cele\bicd-1 Xtro\bicd2 "Mmus\Bicd1, Mmus\Bicd2" "Hsap\BICD2, Hsap\BICD1" " adult stage && oogenesis stage , embryonic stage | early , adult stage | female , embryonic stage | late , larval stage && pupal stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage S8-10B , adult stage && oogenesis stage | stage S1-7 , pupal stage , adult stage | male , adult stage && oogenesis stage | stage >S11 , adult stage && oogenesis stage | stage >=S8 " " germarium region 1--3

, ovary

, oocyte

, cystocyte

{ v egl- } , oocyte | anterior

,

ubiquitous , nurse cell

" ", adult stage && oogenesis stage , oogenesis stage && adult stage | female , embryonic stage | early " " germarium region 2b && presumptive oocyte | anterior

, nurse cell

, cystocyte

, oocyte

, germarium region 1 && germline cyst

, ovary

,

ubiquitous , germarium region 2a && presumptive oocyte | anterior

, germarium region 1--3

, germarium region 3 && stage S1 oocyte | posterior

" "lethal,dominant,maternal effect,recessive,uncoordinated,female fertile,female sterile,male fertile,female semi-sterile,partially lethal - majority die,some die during embryonic stage,locomotor behavior defective,neurophysiology defective,lethal - all die before end of P-stage,some die during P-stage,wild-type,viable" "hemocyte,embryonic head,embryonic thorax,embryo,macrophage,anterior,egg chamber,nurse cell ring canal,oocyte,germline cyst,ovary,synaptonemal complex,synaptonemal complex | ectopic,dorsal appendage,egg,chorion,embryonic neuroblast,embryonic neuroblast & spindleTW119), with BicDHA40.TIvirHA1,embryonic neuroblast & spindle, with BicDHA40.TIvirHA1, Df(2L)TW119,photoreceptor cell | precursor & nucleus,germline clone,pole granule,pole cell,presumptive embryonic/larval central nervous system,egg operculum,ovariole,oocyte nucleus,microtubule organizing center & oocyte,follicle cell,yolk granule,embryonic abdomen,ectopic,posterior,embryonic/first instar larval cuticle,photoreceptor cell & nucleusTW119),NMJ bouton,embryonic/larval somatic muscle,embryonic/larval neuromuscular junction,synaptic vesicleTW119),synaptonemal complex | germline clone,cystocyte,cell non-autonomous,centrosome,germarium region 2a,retina,embryonic/larval optic stalk,yolk granuleTW119),embryonic neuroblast & spindle, with Df(2L)TW119/BicDR26,embryonic neuroblast & spindle, with BicDR26, Df(2L)TW119,lipid particlenos.UTR.THsimVP16,border follicle cell" FBgn0004878 cas castor http://flybase.org/reports/FBgn0004878 "FBgn0005769, FBgn0011311, FBgn0011466, FBgn0014137, FBgn0037367" protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement" "generation of neurons ; GO:0048699 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement central nervous system development ; GO:0007417 | inferred from mutant phenotype ventral cord development ; GO:0007419 | non-traceable author statement post-embryonic development ; GO:0009791 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype ganglion mother cell fate determination ; GO:0007402 | traceable author statement regulation of development, heterochronic ; GO:0040034 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype inferred from genetic interaction with nob inferred from genetic interaction with drl" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement "Cas, cas, ming, l(3)neo33, l(3)j1C2, CG2102" "IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG2102 11-Aug-17 DroID_v2017_08 Drer\casz1 - - Xtro\casz1 Mmus\Casz1 Hsap\CASZ1 " embryonic stage , embryonic stage | stage 5 " " neuroblast NB2-3

, neuroblast NB7-2

, neuroblast NB7-4

, neuroblast NB7-1

, midline glial cell

, neuroblast NB6-1

, neuroblast NB3-3

, neuroblast NB3-2

, neuroblast

, procephalic neurogenic region

, ventral midline

, ganglion mother cell

, neuroblast NB2-4

, central nervous system | restricted

, neuroblast NB3-1

, supraesophageal ganglion

, organism | 10-40% egg length

, embryonic central nervous system

, neuroblast NB5-3

, neuroblast NB4-1

, neuroblast NB5-6

, neuroblast NB5-2

, neuroblast MNB

, neuroblast NB3-4

, neuroblast NB1-1

, neuroblast NB5-1

, neuroblast NB2-1

" embryonic stage | stage 9-11 " tritocerebral neuroblast | subset

, protocerebral neuroblast | subset

, deuterocerebral neuroblast | subset

, procephalic neurogenic region | restricted

" "lethal - all die during larval stage,some die during first instar larval stage,some die during second instar larval stage,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective,male,visible,partially lethal - majority die,some die during pupal stage" "mushroom body beta-lobe,adult mushroom body,adult mushroom body beta'-lobe,posterior commissure,U4 neuron,supernumerary,neuroblast,presumptive embryonic/larval central nervous system,neuroblast NB5-6 of thorax,subesophageal ganglion neuron,ellipsoid body,cell non-autonomous,somatic clone,U5 neuron,eye,macrochaeta,trichogen cell,mesothoracic tergum,thoracic neuroblast,neuroblast NB3-3,EL neuron" FBgn0001078 ftz-f1 ftz transcription factor 1 http://flybase.org/reports/FBgn0001078 "FBgn0010807, FBgn0040788" protein_coding_gene "steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN001182613 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Met inferred from physical interaction with gce DNA binding ; GO:0003677 | inferred from direct assay RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | inferred from biological aspect of ancestor with PANTHER:PTN001182613 transcription factor binding ; GO:0008134 | inferred from physical interaction with Met inferred from physical interaction with gce RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 olfactory behavior ; GO:0042048 | inferred from mutant phenotype regulation of development, heterochronic ; GO:0040034 | traceable author statement metamorphosis ; GO:0007552 | traceable author statement instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay metamorphosis ; GO:0007552 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype periodic partitioning ; GO:0007365 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype cell death ; GO:0008219 | traceable author statement juvenile hormone mediated signaling pathway ; GO:0035626 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype response to hormone ; GO:0009725 | traceable author statement response to ecdysone ; GO:0035075 | traceable author statement pupariation ; GO:0035073 | inferred from mutant phenotype pupation ; GO:0035074 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype" RNA polymerase II transcription factor complex ; GO:0090575 | inferred from biological aspect of ancestor with PANTHER:PTN001182613 cytoplasm ; GO:0005737 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay "ftz-F1, betaFTZ-F1, betaftz-f1, beta FTZ-F1, ftzf1, betaftz-F1, FTZ-F1, CG4059, Ftz-F1, bFTZ-F1, alphaftz-f1, alphaFTZ-F1, dFtz-F1alpha, NR5A3, FTZF1, beta-Ftz-F1, l(3)03649, betaFTZF1, alphaFTZF1, Ftz-f1, FIP1, DmFTZ-F1, ftz-f1alpha, DEP1, FTZ-F1alpha, dFTZ-F1alpha, CG13378, ftz-f1, BFTZ-F1, FTZ-Fl, beta Ftz-f1, FTZ-F1A, betaFtz-f1, FTZf1alpha, beta-FTZ-F1, betaFtz-F1, betaftzf1, dmFTZ-f1" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type, IPR016355:Nuclear hormone receptor family 5" CG4059 11-Aug-17 DroID_v2017_08 "Drer\nr5a2, Drer\nr5a1a, Drer\nr5a5, Drer\nr5a1b" - "Cele\nhr-119, Cele\nhr-8, Cele\Y67D8B.2, Cele\nhr-88, Cele\nhr-31, Cele\unc-55, Cele\nhr-25, Cele\nhr-97, Cele\nhr-5, Cele\nhr-3, Cele\nhr-91" "Xtro\nr5a1, Xtro\nr5a2" "Mmus\Nr5a1, Mmus\Nr5a2" "Hsap\NR5A1, Hsap\NR5A2" " embryonic stage , embryonic stage | late , prepupal stage | 6-8 hr , adult stage , embryonic stage | early , embryonic stage | 14-22 hr " " embryonic stage | 16-19 hr , larval stage && adult stage , embryonic stage | late , prepupal stage , embryonic stage | early " "lethal,recessive,neuroanatomy defective,viable,fertile,maternal effect,pair rule phenotype,non-rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,smell perception defective,germline clone,partially,lethal - all die before end of pupal stage,some die during pupal stage,visible,increased cell death,heat sensitive,developmental rate defective,wild-type,lethal - all die before end of prepupal stage,some die during prepupal stage,decreased cell death,lethal - all die before end of larval stage,majority die during third instar larval stage,some die during second instar larval stage" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,embryonic/larval cuticle,mushroom body | adult stage,adult mushroom body,abdominal 9 ventral denticle belt,denticle belt,parasegment,abdominal 1 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,mesothoracic ventral denticle belt,parasegment 2,parasegment 4,parasegment 6,parasegment 8,parasegment 10,parasegment 12,parasegment 14,embryo,macrochaeta,embryonic/larval salivary gland,Malpighian tubule,optic lobe,larval neuromere,leg,wing disc,midgut,cuticle,maternal effect,segment,head,pupal cuticle,adult head,salivary gland,heat sensitive,cephalopharyngeal skeleton,embryonic/larval anterior spiracle,embryonic/larval posterior spiracle,embryonic/larval tracheal system,mouth hooks,epicuticle,endocuticle,embryonic/larval spiracle,pupa,femur & macrochaeta,tibia & macrochaeta,ventral thoracic disc,metathoracic leg,embryonic/first instar larval cuticle,embryonic epidermis,embryonic segment,germline clone,embryonic head,dorsal,embryonic thorax,heart primordium,embryonic abdominal segment 1 & muscle founder cell,embryonic abdominal segment 3 & muscle founder cell,embryonic abdominal segment 1 & cardioblast,embryonic abdominal segment 3 & cardioblast,embryonic/larval salivary gland | embryonic stage,prothoracic gland,lipid particlephm.PO,ovariole" FBgn0003870 ttk tramtrack http://flybase.org/reports/FBgn0003870 "FBgn0011319, FBgn0011402, FBgn0011681, FBgn0039865, FBgn0039866" protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q08605 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P17789 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with CoRest POZ domain binding ; GO:0031208 | inferred from direct assay promoter-specific chromatin binding ; GO:1990841 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay" "branching involved in open tracheal system development ; GO:0060446 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype regulation of compound eye cone cell fate specification ; GO:0042682 | inferred from mutant phenotype inferred from genetic interaction with sv R1/R6 development ; GO:0048053 | inferred from mutant phenotype myoblast fate specification ; GO:0048626 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype positive regulation of DNA binding ; GO:0043388 | inferred from direct assay startle response ; GO:0001964 | inferred from mutant phenotype compound eye corneal lens morphogenesis ; GO:0048750 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay dorsal trunk growth, open tracheal system ; GO:0035001 | inferred from mutant phenotype cell fate determination ; GO:0001709 | traceable author statement R7 cell development ; GO:0045467 | traceable author statement locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with HDAC1 R7 cell development ; GO:0045467 | inferred from mutant phenotype compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay transcriptional repressor complex ; GO:0017053 | inferred from physical interaction with CoRest polytene chromosome ; GO:0005700 | inferred from direct assay "ttk, Ttk, tramtrak, ttk69, twk, CG1856, ttkp69, TTK88, CG11558, E(yan)100D, FTZ-F2, oss, Ttk69, ftzf2/ttk, clone 2.9, 5311, 5125, 3540, 1418/06, 1396/14, 1372/08, 1325/15, 1281/04, 1260/10, 1209/10, 1209/05, 1184/16, 1119/04, 1049/07, 0702/07, 0438/31, 0250/25, 0037/17, ttk/FTZ-F2, osn, ovs, l(3)j7B8, l(3)j2A1, l(3)02667, ftz-f2, anon-EST:Liang-2.9, Ttk88, TTKA, TTK, TTK69" "IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type, IPR000210:BTB/POZ domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1856 11-Aug-17 DroID_v2017_08 Drer\zbtb20 - "Cele\btb-13, Cele\sdz-28" - "Mmus\Zbtb18, Mmus\Zbtb24" "Hsap\ZBTB9, Hsap\ZBTB45, Hsap\ZBTB24" " embryonic stage | stage >=7 , embryonic stage | syncytial blastoderm , embryonic stage | gastrula , embryonic stage | early , embryonic stage | stage 9-11 , adult stage , embryonic stage | extended germ band , embryonic stage | stage >=8 , embryonic stage | stage 9 " " pole cell

,

ubiquitous , yolk nucleus | restricted

, mesoderm | restricted

, stomodeum

, posterior midgut proper primordium

, anterior midgut proper primordium

,

segment polarity , tracheal pit

, ectoderm | restricted

" " pupal stage , pupal stage | >=36 hr " " secondary pigment cell

, photoreceptor cell

, primary pigment cell

, vibrissae | subset

, tertiary pigment cell

, cone cell

" "lethal,viable,neuroanatomy defective,visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,stress response defective,behavior defective,sleep defective,male limited,partially lethal - majority die,visual behavior defective,semidominant,cell lethalcell lethal,female sterile,cell shape defective,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,mitotic cell cycle defective,dominant,increased cell death,decreased cell size" "border follicle cell,somatic clone,embryonic/larval dorsal trunk,eye,lens,eye photoreceptor cell,rhabdomere,ommatidial precursor cluster,abdominal lateral pentascolopidial chordotonal organ lch5,lch5 neuron,supernumerary,ommatidium,interommatidial bristle,photoreceptor cell R7,cone cell,Kenyon cell,adult mushroom body,sensory neuron,presumptive embryonic/larval peripheral nervous system,thecogen cell,scolopidial dendritic cap cell,external sensory organ,socket,trichogen cell,tormogen cell,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,neuron,macrochaeta,scolopale,microchaeta,dorsal appendage,maternal effect,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere R7,rhabdomere R8,egg chamber,egg,follicle cell,oocyte,germline clone,extended germ band embryo,heat sensitive,multidendritic neuron,chordotonal organ,scolopidial neuron,macrochaeta & leg,commissure,longitudinal connective,exit glial cell,presumptive embryonic/larval tracheal system,embryonic/larval visceral branch,embryonic/larval dorsal branch,embryonic/larval lateral trunk,embryonic/larval cuticle,procuticle,taenidium,taenidial fold,thecogen cell & peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic epidermis,filzkorper,mouth hooks,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,embryonic/larval glial cell,cell autonomous,midline glial cell,embryonic head,embryonic/first instar larval cuticle,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,dorsal triple row,mechanosensory ventral triple row bristle,eye disc,photoreceptor cell R4,photoreceptor cell R3,wing,dorsal mesothoracic disc & sensory mother cellBx-MS1096,intersegmental nerve,interface glial cell,ventral nerve cord primordium,mitotic cell cycleGMR.PF,ommatidium | adult stage,eye disc | pupal stage,ommatidium | pupal stage,cone cell | pupal stage,photoreceptor cell | pupal stage,medial triple row,chemosensory ventral triple row bristle,sensory mother cell & dorsal mesothoracic discBx-MS1096,ventral triple row,photoreceptor cell,eye-antennal disc,morphogenetic furrow,lamina anlage glial cell,subretinal glial cell,lamina neuropil,peripheral nervous system,ommatidium | third instar larval stage,photoreceptor cell R1 | third instar larval stage,photoreceptor cell R6 | third instar larval stage,photoreceptor cell R7 | third instar larval stage,cone cell | third instar larval stage,equatorial cone cell,polar cone cell,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite" DRSC17091 IE -1.233048772 -2.693205836 -1.676500078 2.398660052 0.212095878 0.200082962 FBgn0014388 sty sprouty http://flybase.org/reports/FBgn0014388 - protein_coding_gene - "ovarian follicle cell development ; GO:0030707 | traceable author statement regulation of compound eye photoreceptor development ; GO:0045314 | inferred from genetic interaction with csw torso signaling pathway ; GO:0008293 | non-traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype morphogenesis of a branching structure ; GO:0001763 | traceable author statement negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | non-traceable author statement negative regulation of fibroblast growth factor receptor signaling pathway ; GO:0040037 | traceable author statement branching involved in open tracheal system development ; GO:0060446 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | traceable author statement negative regulation of Ras protein signal transduction ; GO:0046580 | traceable author statement secondary branching, open tracheal system ; GO:0007429 | traceable author statement anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | traceable author statement tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement muscle fiber development ; GO:0048747 | inferred from mutant phenotype negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | traceable author statement negative regulation of fibroblast growth factor receptor signaling pathway ; GO:0040037 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | traceable author statement negative regulation of signal transduction ; GO:0009968 | traceable author statement" intracellular ; GO:0005622 | traceable author statement intracellular ; GO:0005622 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay "Spry, spry, CS3-3, Sry, Sty, dSPRY, CG1921, sty, STY" "IPR007875:Sprouty, IPR015943:WD40/YVTN repeat-like-containing domain" CG1921 11-Aug-17 DroID_v2017_08 "Drer\spry1, Drer\spry4, Drer\spry2" - Cele\crm-1 "Xtro\spry4, Xtro\spry1, Xtro\spry2, Xtro\spry3" "Mmus\Spry3, Mmus\Spry1, Mmus\Spry2, Mmus\Notch2, Mmus\Spry4" "Hsap\SPRY4, Hsap\SPRY2, Hsap\SPRY3, Hsap\SPRY1" " embryonic stage | late , embryonic stage | stage >=12 , embryonic stage | 5-22 hr " " neuron &&of ventral nerve cord

, embryonic/larval tracheal system

, oenocyte

, midline glial cell

, embryonic/larval dorsal vessel

" "visible,viable,fertile,neuroanatomy defective,lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,dominant" "wing vein,synapse,eye,fascicle | third instar larval stage,embryonic/larval dorsal branch,embryonic/larval ganglionic branch,ommatidium,cone cell,mystery cell,chordotonal organ,midline glial cell,egg,dorsal appendage,ganglionic branch 2,cell non-autonomous,somatic clone,embryonic/larval dorsal branch 1,lateral trunk anterior branch,lateral trunk posterior branch,embryonic/larval visceral branch,ovary,germline clone,terminal tracheal cell,supernumerary,outer photoreceptor cell,dorsal air sac primordium,maternal effect,embryonic/larval tracheal system,eye photoreceptor cell,primary pigment cell,pigment cell,five-cell ommatidial precursor cluster,ommatidial precursor cluster,wing,hemocyte | late embryonic stage,wing vein L3,wing vein L2,wing vein L4,photoreceptor cell R1,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R6,photoreceptor cell R7,interommatidial bristle,embryo,muscle founder cell,embryonic/larval optic stalk surface glial cell | third instar larval stage" FBgn0004635 rho rhomboid http://flybase.org/reports/FBgn0004635 "FBgn0003251, FBgn0003972, FBgn0026834" protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model inferred from direct assay inferred from mutant phenotype inferred from genetic interaction with spi "open tracheal system development ; GO:0007424 | traceable author statement salivary gland boundary specification ; GO:0007432 | non-traceable author statement epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement peptide bond cleavage involved in epidermal growth factor receptor ligand maturation ; GO:0038005 | inferred from genetic interaction with spi imaginal disc-derived wing vein specification ; GO:0007474 | traceable author statement behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype salivary gland development ; GO:0007431 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype tracheal pit formation in open tracheal system ; GO:0035202 | traceable author statement imaginal disc-derived wing vein specification ; GO:0007474 | non-traceable author statement positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | traceable author statement epithelial cell proliferation involved in Malpighian tubule morphogenesis ; GO:0061331 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype oenocyte development ; GO:0007438 | inferred from mutant phenotype inferred from genetic interaction with abd-A wing cell fate specification ; GO:0035311 | inferred from mutant phenotype stem cell fate commitment ; GO:0048865 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement axonogenesis ; GO:0007409 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype morphogenesis of a branching structure ; GO:0001763 | non-traceable author statement single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002610, InterPro:IPR017213, InterPro:IPR022764 plasma membrane ; GO:0005886 | NOT inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from sequence or structural similarity endoplasmic reticulum ; GO:0005783 | NOT inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay integral component of membrane ; GO:0016021 | traceable author statement" "rho, Dmel\rho, Rho-1, CG1004, Rho1, rhomboid/veinlet, ve, rho1, rho-1, Rho, DMRHOb, RHO, rhom, RHOb, DMRHO, DRORHO, Ve, DMRHOa, Dmrho, iks, DmRho1" "IPR002610:Peptidase S54, rhomboid, IPR017213:Peptidase S54, rhomboid, metazoan, IPR022764:Peptidase S54, rhomboid domain" CG1004 11-Aug-17 DroID_v2017_08 "Drer\rhbdl3, Drer\rhbdl1, Drer\rhbdl2" - "Cele\rom-2, Cele\rom-1" Xtro\rhbdl2 "Mmus\Rhbdl3, Mmus\Rhbdl2, Mmus\Rhbdl1" "Hsap\RHBDL3, Hsap\RHBDL2, Hsap\RHBDL1" " pupal stage , oogenesis stage | early , embryonic stage | stage 10-15 , embryonic stage , larval stage&&pupal stage , embryonic stage | stage >=12 , embryonic stage&&pupal stage&&adult stage , adult stage && oogenesis stage , embryonic stage | stage 6,7 , embryonic stage | stage 5 , oogenesis stage , oogenesis stage | late , embryonic stage | stage >=13 , embryonic stage | stage 7-12 " " crossvein

, follicle cell

{ 0 Egfr* } , wing vein L4

, embryonic central brain

subset , tracheal pit

, wing vein L3

, wing vein L2 | precursor

, central nervous system | segmentally repeated

, wing vein L1

, wing vein L5 | precursor

, wing vein L4 | precursor

, wing vein L5

, follicle cell

{ - grk* } , wing vein | precursor

, Malpighian tubule tip cell

, follicle cell

{ + fs(1)K10* } , wing vein L2

, mesectoderm

, wing vein L3 | precursor

, wing vein L1 | precursor

, organism | ventro-lateral & restricted

, wing vein

, follicle cell

{ 0 grk* } , follicle cell

, chordotonal organ | precursor

,

segment boundary , embryonic foregut

ventral & anterior , ventral midline

, follicle cell

{ - Egfr* } " " larval stage | third instar , adult stage && oogenesis stage " " photoreceptor cell R2 | presumptive

, ommatidium

, photoreceptor cell R5 | presumptive

, follicle cell

, photoreceptor cell R8 | presumptive

" "visible,recessive,viable,dominant,learning defective,memory defective,chemical sensitive,lethal - all die before end of embryonic stage,neuroanatomy defective,some die during embryonic stage,lethal,heat sensitive,flightless,increased cell number" ",tracheal system,wing,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,scolopidium,scolopidial dendritic cap cell,scolopidial neuron,Keilin's organ,antenno-maxillary complex,abdominal lateral longitudinal muscle,abdominal dorsal oblique muscle,abdominal dorsal acute muscle,abdominal ventral longitudinal muscle,somatic muscle,abdominal ventral oblique muscle,midline glial cell,RP3 motor neuron,wing vein,abdominal lateral pentascolopidial chordotonal organ,abdominal ventral monoscolopidial chordotonal organ,ventral thoracic disc primordium,dorsal mesothoracic disc primordium,RP2 motor neuron,dorsal neurohemal organ,bract,dorsal appendage,eye,segment border muscle,abdominal dorsal adult muscle precursor cell,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,ventral nerve cord commissure,embryonic/larval salivary gland,wing margin,chordotonal organ,embryonic/larval optic lobe,adult eye primordium,optic lobe,Bolwig organ,egg,crossvein,interommatidial bristle,ommatidium,yellow ommatidium,embryonic/first instar larval cuticle,abdominal ventral denticle belt,presumptive embryonic/larval central nervous system,commissure,longitudinal connective,sensory neuron,motor neuron,embryonic/larval dorsal trunk,dendritic arborizing neuron,axon,embryonic/larval tracheal system,embryonic/larval visceral branch,embryonic/larval oenocyte,pale ommatidium,tracheal branch primordium,cephalopharyngeal skeleton,anterior commissure,posterior commissure,genital disc primordium,embryonic ventral nervous system,anal pad,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,embryonic Malpighian tubule,embryonic central brain,circumesophageal tract,adult salivary gland primordium,embryonic ventral epidermis,photoreceptor cell,tracheal primordium,presumptive embryonic/larval tracheal system,mesoderm,lch5 cap attachment cell,lch5 ligament attachment cell,VUM interneuron 1,VUM interneuron 2,VUM interneuron 3,MP1 neuron,A1-7 ventral acute muscle 2,embryonic/larval trachea,VUM neuron,denticle,ganglionic branch 1 |,muscle founder cell |,chorion,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic prothoracic segment,oenocyte primordium,embryonic/larval oenocyte precursor,cone cell,pigment cell,dorsal hair,-109-68,wing disc,posterior crossvein,anterior crossvein" DRSC08734 I -0.746884187 2.111964777 0.278130487 0.250288545 -0.37531931 -0.070061948 FBgn0035656 CG10479 - http://flybase.org/reports/FBgn0035656 protein_coding_gene - - - CG10479 IPR000980:SH2 domain CG10479 11-Aug-17 DroID_v2017_08 - Scer\TEP1 Cele\shc-2 - - - "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0001085 fz frizzled http://flybase.org/reports/FBgn0001085 "FBgn0036418, FBgn0036420" protein_coding_gene "Wnt-activated receptor activity ; GO:0042813 | inferred from direct assay transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity Wnt-activated receptor activity ; GO:0042813 | traceable author statement Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt2, Wnt4, wg" "establishment of tissue polarity ; GO:0007164 | non-traceable author statement <> morphogenesis of a polarized epithelium ; GO:0001738 |... mutant phenotype <> protein localization ; GO:0008104 | traceable author statement <> border follicle cell migration ; GO:0007298 |... mutant phenotype <> establishment of planar polarity ; GO:0001736 |... mutant phenotype <> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <> asymmetric protein localization ; GO:0008105 | traceable author statement <> axon extension ; GO:0048675 |... mutant phenotype <> establishment of cell polarity ; GO:0030010 |... mutant phenotype <> sensory organ precursor cell fate determination ; GO:0016360 |... mutant phenotype <> ommatidial rotation ; GO:0016318 | traceable author statement <> establishment of ommatidial planar polarity ; GO:0042067 |... mutant phenotype <> canonical Wnt signaling pathway ; GO:0060070 |... genetic interaction with wg <> negative regulation of Notch signaling pathway ; GO:0045746 |... mutant phenotype <> establishment or maintenance of cell polarity ; GO:0007163 |... mutant phenotype <> regulation of hemocyte proliferation ; GO:0035206 |... mutant phenotype <> heart development ; GO:0007507 | non-traceable author statement <> positive regulation of axon guidance ; GO:1902669 |... mutant phenotype <> establishment of planar polarity ; GO:0001736 | traceable author statement <> homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 |... mutant phenotype <> salivary gland morphogenesis ; GO:0007435 |... mutant phenotype <> G-protein coupled receptor signaling pathway ; GO:0007186 |... genetic interaction with Gαs <> positive regulation of axon extension ; GO:0045773 |... genetic interaction with DAAM <> ommatidial rotation ; GO:0016318 |... mutant phenotype <> Wnt signaling pathway ; GO:0016055 | non-traceable author statement <> establishment of epithelial cell apical/basal polarity ; GO:0045198 |... mutant phenotype <> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 |... expression pattern inferred from mutant phenotype <> signal transduction ; GO:0007165 |... sequence or structural similarity <> imaginal disc-derived wing hair site selection ; GO:0035320 |... mutant phenotype <> R3/R4 cell fate commitment ; GO:0007464 |... mutant phenotype <> imaginal disc-derived wing morphogenesis ; GO:0007476 |... mutant phenotype <> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 |... mutant phenotype <> R3/R4 cell fate commitment ; GO:0007464 | non-traceable author statement <> Wnt signaling pathway ; GO:0016055 | traceable author statement <> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement <> asymmetric cell division ; GO:0008356 |... mutant phenotype <> regulation of tube length, open tracheal system ; GO:0035159 |... mutant phenotype <> regulation of actin filament bundle assembly ; GO:0032231 |... genetic interaction with Rok <> R3/R4 cell fate commitment ; GO:0007464 | traceable author statement <> compound eye morphogenesis ; GO:0001745 |... mutant phenotype <> imaginal disc-derived wing hair organization ; GO:0035317 |... genetic interaction with ck inferred from genetic interaction with sqh inferred from genetic interaction with Rho1 inferred from genetic interaction with Rok inferred from genetic interaction with zip" plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | non-traceable author statement cell cortex ; GO:0005938 | inferred from direct assay endosome ; GO:0005768 | colocalizes_with inferred from direct assay "fz, Fz, fz1, Fz1, DFz1, CG3646, DFz, frz, FZ, DFZ1, Dfz1, CG17697, fz[[1]], Frz, Dm Fz1, Dfz, dFz" "IPR017981:GPCR, family 2-like, IPR000539:Frizzled protein, IPR015526:Frizzled/secreted frizzled-related protein, IPR020067:Frizzled domain, IPR026552:Frizzled-7" CG17697 11-Aug-17 DroID_v2017_08 "Drer\frzb, Drer\LOC101884738, Drer\fzd7b, Drer\fzd6, Drer\sfrp5, Drer\LOC103908663, Drer\fzd7a, Drer\fzd2, Drer\szl, Drer\fzd3a, Drer\corin, Drer\si:cabz01033205.3, Drer\fzd5, Drer\fzd1, Drer\sfrp1b, Drer\fzd10, Drer\fzd4, Drer\sfrp2l, Drer\fzd8a, Drer\sfrp1a, Drer\sfrp2, Drer\fzd9b, Drer\fzd3b, Drer\fzd8b, Drer\fzd9a, Drer\smo" - "Cele\mig-1, Cele\sfrp-1, Cele\cfz-2, Cele\mom-5, Cele\lin-17" "Xtro\fzd3, Xtro\fzd2, Xtro\col18a1, Xtro\fzd9, Xtro\sfrp2, Xtro\sfrp5, Xtro\fzd10, Xtro\fzd8, Xtro\fzd7, Xtro\sfrpx, Xtro\fzd5, Xtro\fzd6, Xtro\fzd4, Xtro\sfrp1, Xtro\smo, Xtro\mfrp, Xtro\corin, Xtro\frzb, Xtro\frzb2, Xtro\szl" "Mmus\Fzd4, Mmus\Fzd8, Mmus\Frzb, Mmus\Fzd9, Mmus\Fzd5, Mmus\Fzd3, Mmus\Fzd1, Mmus\Fzd2, Mmus\Fzd6, Mmus\Sfrp1, Mmus\Fzd7, Mmus\Sfrp5, Mmus\Corin, Mmus\Sfrp2, Mmus\Mfrp, Mmus\Sfrp4, Mmus\Fzd10, Mmus\Smo" "Hsap\FZD5, Hsap\FZD4, Hsap\MFRP, Hsap\FZD2, Hsap\FZD1, Hsap\SFRP5, Hsap\FZD6, Hsap\FZD7, Hsap\SFRP4, Hsap\CORIN, Hsap\FZD3, Hsap\FZD8, Hsap\SMO, Hsap\FZD9, Hsap\SFRP1, Hsap\FZD10, Hsap\FRZB, Hsap\SFRP2" " pupal stage , larval stage | third instar , embryonic stage , larval stage , adult stage | female , oogenesis stage && adult stage | female , embryonic stage | early , embryonic stage--pupal stage " " central nervous system

, larval brain

, eye-antennal disc

, ovary

, embryonic/larval proventriculus

,

ubiquitous , morphogenetic furrow

, wing

, epidermis

, imaginal disc

, ventral nerve cord

" " pupal stage , larval stage | third instar " " wing

, dorsal mesothoracic disc

, larval central nervous system

, imaginal disc

" "planar polarity defective,visible,viable,fertile,dominant,heat sensitive,wild-type,somatic clone,cell polarity defective,recessive,neuroanatomy defective,cell non-autonomous,cold sensitive,cell autonomous" "wing hair,wing,joint,ectopic,leg,macrochaeta,macrochaeta & adult thorax,ommatidium,heat sensitive,eye,wing & microchaeta | distal,supernumerary,embryonic epidermis,somatic clone,photoreceptor cell R4,photoreceptor cell R3,axon & dorsal cluster neuron,trichome & pleural membrane | somatic clone | cell non-autonomous,trichome & pleural membrane | somatic clone,trichome & adult abdomen | somatic clone | cell non-autonomous,trichome & adult abdomen | somatic clone,border follicle cell,polar follicle cell,cell non-autonomous,trichome & pleural membrane | somatic cloneUbx.PdC, fzUAS.cSa,trichome & pleural membrane | somatic clone | cell non-autonomousUbx.PdC, fzUAS.cSa,trichome & pleural membraneen-e16E, fzUAS.cSa,dorsal wing blade,lens,cold sensitive,wing & macrochaeta,RP2 motor neuron,macrochaeta & adult abdomen | somatic clone | cell non-autonomous,microchaeta & adult abdomen | somatic clone | cell non-autonomous,microchaeta & adult thorax | somatic clone | cell non-autonomous,bract,tarsal segment,wing disc,presumptive embryonic salivary gland,eye photoreceptor cell,wing cell,trichome & pleural membranehh-Gal4, fzUAS.cSa,embryonic/larval dorsal trunk,mesothoracic tergum & sensory mother cell & spindle,external sensory organ precursor cell I,external sensory organ precursor cell I & spindle,external sensory organ precursor cell I & centrosome,socket,spindle & external sensory organ precursor cell I,macrochaeta & eye,trichogen cell,embryonic neuroblast,wing & microchaeta,wing margin bristle,sensory mother cell,spindle,tarsal segment 1 & joint,tarsal segment 2,tarsal segment 3,tarsal segment 4,trichome & pleural membrane,trichome & abdominal tergite,wing margin,mesothoracic tergum,wing hair | P-stage,wing & microchaeta | distalDll-md23,microchaeta,sensory mother cell & spindleap-md52,denticle belt,embryonic/first instar larval cuticle,wing hair & 1st posterior cellptc-559.1,wing & microchaetaptc-559.1,anterior compartment,anterior/posterior compartment boundary,trichome & adult abdomenhh-Gal4,trichome & pleural membranehh-Gal4,trichome & pleural membrane‘±Tub84B.PL,trichome & pleural membrane | somatic cloneUbx.PdC,trichome & pleural membrane | somatic clone | cell non-autonomousUbx.PdC,trichome & pleural membrane | somatic cloneUbx.PdC, fz15,trichome & pleural membrane | somatic clone | cell non-autonomousUbx.PdC, fz15,trichome & pleural membraneen-e16E, fz15,trichome & pleural membranehh-Gal4, fz21,trichome & pleural membraneen-e16E,denticle row 1,dorsal triple row,medial triple row,ventral triple row,lymph gland derived hemocyte | third instar larval stage,thorax" FBgn0023519 mRpL16 mitochondrial ribosomal protein L16 http://flybase.org/reports/FBgn0023519 FBgn0019893 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049642 structural constituent of ribosome ; GO:0003735 | traceable author statement rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000259456 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049642 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049642 "L16, anon-2Bd, EG:63B12.2, CG3109, D-15, mRpL16, D15" "IPR000114:Ribosomal protein L16, IPR016180:Ribosomal protein L10e/L16" CG3109 11-Aug-17 DroID_v2017_08 Drer\mrpl16 Scer\MRPL16 "Cele\mrpl-16, Cele\tmem-231" Xtro\mrpl16 Mmus\Mrpl16 Hsap\MRPL16 "viable,visible" trichogen cell FBgn0035854 CG8005 - http://flybase.org/reports/FBgn0035854 protein_coding_gene deoxyhypusine synthase activity ; GO:0034038 | inferred from biological aspect of ancestor with PANTHER:PTN000193988 peptidyl-lysine modification to peptidyl-hypusine ; GO:0008612 | inferred from biological aspect of ancestor with PANTHER:PTN000193988 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000193988 CG8005 "IPR002773:Deoxyhypusine synthase, IPR029035:DHS-like NAD/FAD-binding domain" CG8005 11-Aug-17 DroID_v2017_08 Drer\dhps Scer\DYS1 Cele\dhps-1 Xtro\dhps Mmus\Dhps Hsap\DHPS "viable,visible" trichogen cell FBgn0004198 ct cut http://flybase.org/reports/FBgn0004198 "FBgn0000383, FBgn0001303, FBgn0029953, FBgn0062500" protein_coding_gene RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001019067 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype antennal development ; GO:0007469 | inferred from expression pattern antennal development ; GO:0007469 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement Malpighian tubule morphogenesis ; GO:0007443 | traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement Golgi vesicle transport ; GO:0048193 | inferred from biological aspect of ancestor with PANTHER:PTN000361901 negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype inferred from genetic interaction with kn antennal joint development ; GO:0048098 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | traceable author statement female gonad development ; GO:0008585 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype central nervous system development ; GO:0007417 | traceable author statement Malpighian tubule bud morphogenesis ; GO:0061332 | inferred from genetic interaction with Kr formation of a compartment boundary ; GO:0060288 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype" Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000361901 nucleus ; GO:0005634 | inferred from direct assay "Ct, Cut, cut, CG11387, kf, l(1)VE614, l(1)7Bb, l(1)7Ba, BcDNA:GH10590, ct, CT, CUT" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR003350:CUT domain, IPR009057:Homeobox domain-like, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011990:Tetratricopeptide-like helical domain, IPR010982:Lambda repressor-like, DNA-binding domain" CG11387 11-Aug-17 DroID_v2017_08 "Drer\onecut3a, Drer\cux1a, Drer\cux2a, Drer\cux1b, Drer\onecut3b, Drer\onecut1, Drer\cux2b, Drer\onecut2" Scer\COY1 Cele\ceh-44 "Xtro\cux2, Xtro\onecut1, Xtro\cux1" "Mmus\Cux2, Mmus\Onecut1, Mmus\Onecut3, Mmus\Onecut2, Mmus\Cux1" "Hsap\ONECUT2, Hsap\CUX1, Hsap\CUX2, Hsap\ONECUT3, Hsap\ONECUT1" " embryonic stage | >5-6 hr , pupal stage , embryonic stage , adult stage , embryonic stage | >6-7 hr " " embryonic/larval posterior spiracle | surrounding

, embryonic/larval anterior spiracle | surrounding

, adult head

, external sensory organ

, embryonic central nervous system | presumptive | restricted

, Malpighian tubule

" " embryonic stage | 8 hr , prepupal stage | 0-2 hr , embryonic stage | >6-7 hr , adult stage , larval stage | third instar , embryonic stage | 10 hr , embryonic stage | 6-7 hr , embryonic stage | 5-6 hr , embryonic stage , embryonic stage | >5-6 hr , pupal stage | stage P6 , pupal stage | 24 hr , embryonic stage | stage > 9 , pupal stage | 6 hr , larval stage--adult stage , embryonic stage |>6 hr , prepupal stage | 3 hr , embryonic stage | stage 13 , adult stage && oogenesis stage | stage S2-14 " " desB neuron

, chemosensory sensory organ | precursor dorsal mesothoracic disc

, embryonic central nervous system | presumptive | restricted

, adult muscle system

, myoblast && mesothoracic tergum | distal

, v'esB neuron

, vesC neuron

, dorsal mesothoracic disc | restricted

, desD neuron

, des2 neuron

, lobula plate cortex

, chordotonal organ

, desC neuron

, lesA neuron

, lesB neuron

, embryonic/larval posterior spiracle | surrounding

, macrochaeta

, interommatidial bristle | precursor

, external sensory organ

, Malpighian tubule

, embryonic/larval anterior spiracle | surrounding

, pioneer neuron | precursor

, les3 neuron

, embryonic Malpighian tubule

, microchaeta

, chemosensory sensory organ &&of dorsal mesothoracic disc

, v'es3 neuron

, ventral thoracic disc | restricted

, cone cell

, v'es2 neuron

, tarsus | precursor

, vesB neuron

, imaginal tracheoblast

, v'esA neuron

, follicle cell

, adepithelial cell

, myoblast && mesothoracic tergum | proximal

, medulla cortex

, lesC neuron

" "lethal,recessive,visible,melanotic mass phenotype,homeotic,viable,neuroanatomy defective,wild-type,gravitaxis defective,fertile,male,reduced,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,male sterile,body color defective,female,partially lethal - majority die,poor,eye color defective,behavior defective,female sterile,cold sensitive,decreased cell number,somatic clone,mitotic cell cycle defective,cell lethal,germline clone,partially,increased cell size,neurophysiology defective,auditory perception defective,locomotor rhythm defective,planar polarity defective,hyperplasia" "femur,melanotic mass | third instar larval stage,melanotic mass | pupal stage,embryonic/larval hemocyte,supernumerary | third instar larval stage,leg,ectopic,antenna,wing,macrochaeta & wing,vibrissae,adult head,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,precursor,wing margin,wing blade,wing margin bristle,medial triple row,dorsal double row,chemosensory ventral triple row bristle,mechanosensory ventral triple row bristle,wing & macrochaeta | posterior,dorsal-ventral compartment boundary of the wing,macrochaeta,scutum & macrochaeta,scutellum & macrochaeta,scutellar bristle,Malpighian tubule,adult spiracle,external sensory organ,central nervous system,triple row,ventral triple row,dorsal triple row,tergite,arista,eye,nurse cell,oocyte nucleus,egg chamber,chordotonal organ,scolopidium,thorax,wing vein,adult antennal lobe projection neuron DM5 lPN,antennal lobe glomerulus DM5,adult antennal lobe projection neuron VA5 lPN,antennal lobe glomerulus VA5,adult antennal lobe projection neuron DM2 lPN,antennal lobe glomerulus DM2,adult antennal lobe projection neuron DM1 lPN,antennal lobe glomerulus DM1,adult antennal lobe projection neuron DA1 vPN,antennal lobe projection neuron vPN,subesophageal ganglion,antennal lobe glomerulus VA1v,pigment cell,spiracular chamber,filzkorper,spiracular sense organ (obsolete FBbt00000431),multidendritic neuron,follicle cell,somatic clone,posterior spiracle primordium,nurse cell ring canal,dorsal multidendritic neuron ddaA,lateral multidendritic neuron ldaB,germarium,joint & antenna | somatic clone,epidermal cell,dendrite | somatic clone,indirect flight muscle,adepithelial cell of wing disc,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,mechanosensory chaeta,supernumerary,multidendritic dendrite,abdominal posterior ventral multidendritic neuron vdap,dendrite221,abdominal posterior ventral multidendritic neuron vdap | third instar larval stage,dorsal multidendritic neuron ddaB,dorsal multidendritic neuron ddaE,antennal lobe,antennal lobe projection neuron,class IV dendritic arborizing neuron,dendriteppk.PG,dorsal-ventral compartment boundary of the wing | third instar larval stage,actin cytoskeleton | ectopicsalm-459.2,trichogen cell,interommatidial bristle,embryonic/larval lymph gland" DRSC18757 EK -1.176195352 -0.123216743 0.186554477 -1.768505502 2.690592383 3.64887503 FBgn0038037 Cyp9f2 Cyp9f2 http://flybase.org/reports/FBgn0038037 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 wing disc development ; GO:0035220 | inferred from mutant phenotype" - "9f2, anon-EST:Posey150, CG11466, Cyp9f2, Cyp 9f2, Cyp9F2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG11466 11-Aug-17 DroID_v2017_08 "Drer\cyp26a1, Drer\tbxas1, Drer\cyp3c2, Drer\cyp3c1, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp3c3, Drer\cyp4t8, Drer\cyp3a65, Drer\cyp4f3, Drer\cyp3c4" "Scer\ERG5, Scer\ERG11" "Cele\cyp-25A4, Cele\cyp-43A1, Cele\cyp-13A5, Cele\cyp-13A8, Cele\cyp-13A7, Cele\cyp-13A3, Cele\cyp-37B1, Cele\cyp-29A2, Cele\cyp-25A6, Cele\cyp-44A1, Cele\cyp-13A2, Cele\cyp-25A3, Cele\cyp-25A1, Cele\cyp-13B2, Cele\cyp-13A4, Cele\cyp-32B1, Cele\cyp-13A11, Cele\cyp-29A4, Cele\cyp-13A12, Cele\cyp-13A1, Cele\cyp-25A2, Cele\cyp-13A6, Cele\cyp-32A1, Cele\cyp-29A3, Cele\cyp-13A10, Cele\cyp-13B1, Cele\cyp-31A2, Cele\cyp-42A1, Cele\cyp-31A3, Cele\cyp-23A1" "Xtro\tbxas1, Xtro\LOC100487846, Xtro\LOC100487054, Xtro\cyp3a5, Xtro\cyp3a4, Xtro\LOC100494419" "Mmus\Cyp3a25, Mmus\Cyp3a59, Mmus\Cyp3a11, Mmus\Cyp4a32, Mmus\Cyp4f15, Mmus\Cyp4v3, Mmus\Cyp3a41b, Mmus\Cyp4f39, Mmus\Cyp4a12b, Mmus\Cyp4a31, Mmus\Cyp4f14, Mmus\Cyp3a41a, Mmus\Cyp4a10, Mmus\Tbxas1, Mmus\Cyp3a57, Mmus\Cyp3a16, Mmus\Cyp4f16, Mmus\Cyp3a44, Mmus\Cyp4f13, Mmus\Cyp4b1, Mmus\Cyp4a14, Mmus\Cyp4f37, Mmus\Cyp3a13, Mmus\Cyp4a12a, Mmus\Cyp26a1, Mmus\Cyp4f18" "Hsap\CYP3A7-CYP3A51P, Hsap\CYP4F22, Hsap\CYP4V2, Hsap\CYP3A7, Hsap\CYP4F3, Hsap\CYP4B1, Hsap\CYP4A22, Hsap\CYP4F12, Hsap\CYP4F8, Hsap\CYP4A11, Hsap\CYP3A5, Hsap\CYP26A1, Hsap\CYP3A43, Hsap\TBXAS1, Hsap\CYP3A4, Hsap\CYP4Z1, Hsap\CYP4F11, Hsap\CYP4F2, Hsap\CYP4X1" "viable,fertile" wing margin FBgn0034800 CG3788 - http://flybase.org/reports/FBgn0034800 protein_coding_gene uridine phosphorylase activity ; GO:0004850 | inferred from electronic annotation with InterPro:IPR010059 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 nucleotide catabolic process ; GO:0009166 | inferred from electronic annotation with InterPro:IPR010059 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010059 CG3788 "IPR000845:Nucleoside phosphorylase domain, IPR010059:Uridine phosphorylase, eukaryotic, IPR018016:Nucleoside phosphorylase, conserved site" CG3788 11-Aug-17 DroID_v2017_08 "Drer\upp2, Drer\upp1" - Cele\upp-1 "Xtro\upp2, Xtro\upp1" "Mmus\Upp1, Mmus\Upp2" "Hsap\UPP2, Hsap\UPP1" viable DRSC24502 K -0.448041247 0.7686463 -0.261816704 0.871332714 -0.812069781 2.056670242 FBgn0035995 CG3529 - http://flybase.org/reports/FBgn0035995 protein_coding_gene - "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002014, InterPro:IPR004152" intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR004152 "CG3529, DmTOM1" "IPR002014:VHS domain, IPR004152:GAT domain, IPR008942:ENTH/VHS, IPR014645:Target of Myb protein 1, IPR027429:Target of Myb1-like 2" CG3529 11-Aug-17 DroID_v2017_08 "Drer\gga3, Drer\tom1, Drer\tom1l2, Drer\si:ch73-157i16.3, Drer\gga1" "Scer\GGA2, Scer\LSB5, Scer\GGA1" "Cele\C07A12.7, Cele\apt-9" "Xtro\gga1, Xtro\gga3, Xtro\tom1, Xtro\tom1l1, Xtro\tom1l2" "Mmus\Gga2, Mmus\Tom1l2, Mmus\Gga1, Mmus\Tom1l1, Mmus\Gga3, Mmus\Tom1" "Hsap\GGA3, Hsap\TOM1L2, Hsap\GGA2, Hsap\TOM1L1, Hsap\TOM1, Hsap\GGA1" "viable,fertile" DRSC25300 K -0.25227707 0.619442887 -0.236507331 -0.832990081 1.618489585 -0.615156216 FBgn0262512 Vha14-1 Vacuolar H[+] ATPase 14kD subunit 1 http://flybase.org/reports/FBgn0262512 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR005772 ATPase coupled ion transmembrane transporter activity ; GO:0042625 | inferred from biological aspect of ancestor with PANTHER:PTN001015339 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR005772 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 "plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD:S000003252" "vha14-1, CG8210, Vha14-1, vha14, ATPase, Vha14, VAF1_DROME, l(2)SH1248, l(2)SH2 1248, ATP6V1F" "IPR005772:ATPase, V1 complex, subunit F, eukaryotic, IPR008218:ATPase, V1 complex, subunit F" CG8210 11-Aug-17 DroID_v2017_08 Drer\atp6v1f Scer\VMA7 Cele\vha-9 Xtro\atp6v1f Mmus\Atp6v1f Hsap\ATP6V1F " adult stage , adult stage | female , adult stage | male , embryonic stage -- adult stage " " adult abdomen

, adult head

, adult thorax

" FBgn0036806 Cyp12c1 Cyp12c1 http://flybase.org/reports/FBgn0036806 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "12c1, CG4120, Cyp12c1, cyp12c1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG4120 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-91i10.3, Drer\cyp27a1.2, Drer\cyp24a1, Drer\cyp27b1, Drer\cyp27c1, Drer\si:ch211-113j14.1, Drer\cyp11a2, Drer\cyp27a7, Drer\zgc:136333, Drer\cyp27a1.4, Drer\cyp11c1" Scer\DIT2 "Cele\ZK177.4, Cele\cyp-33D1, Cele\cyp-35B3, Cele\cyp-35A3, Cele\cyp-35A5, Cele\cyp-44A1" "Xtro\cyp24a1, Xtro\cyp27c1, Xtro\cyp27a1, Xtro\cyp11a1, Xtro\cyp27b1, Xtro\LOC100145331" "Mmus\Cyp11b1, Mmus\Cyp11a1, Mmus\Cyp27b1, Mmus\Cyp27a1, Mmus\Cyp24a1, Mmus\Cyp11b2" "Hsap\CYP27B1, Hsap\CYP27C1, Hsap\CYP27A1, Hsap\CYP11B1, Hsap\CYP11A1, Hsap\CYP11B2, Hsap\CYP24A1" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039852 nyo nyobe http://flybase.org/reports/FBgn0039852 protein_coding_gene - apical constriction ; GO:0003383 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model "clone 2.47, anon-EST:Liang-2.47, nyo, CG1499" "IPR001507:Zona pellucida domain, IPR003609:PAN/Apple domain" CG1499 11-Aug-17 DroID_v2017_08 - - "Cele\C34C12.7, Cele\noah-1, Cele\cutl-17, Cele\cutl-27, Cele\H03E18.1, Cele\R07A4.4, Cele\H42K12.3, Cele\T23F1.5, Cele\ZC449.2, Cele\C16D9.1, Cele\F32B4.8, Cele\ZC449.1, Cele\T26C5.2, Cele\let-653, Cele\noah-2, Cele\cutl-18, Cele\F52C9.5, Cele\cutl-28" - - - "viable,visible,partially lethal - majority die,some die during pupal stage" "denticle,wing" FBgn0029879 APC7 Anaphase Promoting Complex subunit 7 http://flybase.org/reports/FBgn0029879 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from genetic interaction with Cdc23 positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from genetic interaction with Cdc23 "anaphase-promoting complex ; GO:0005680 | inferred from physical interaction with Cdc27, Cdc23" "CG14444, Apc7, APC7" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG14444 11-Aug-17 DroID_v2017_08 Drer\anapc7 - Cele\mat-1 Xtro\anapc7 Mmus\Anapc7 Hsap\ANAPC7 "viable,fertile" FBgn0267796 Tmc Transmembrane channel-like http://flybase.org/reports/FBgn0267796 protein_coding_gene molecular_function ; GO:0003674 | no biological data available locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012496 dendrite ; GO:0030425 | inferred from mutant phenotype "CG14177, CG3280, CG46121, Tmc, tmc" IPR012496:TMC CG46121 11-Aug-17 DroID_v2017_08 "Drer\tmc3, Drer\tmc6b, Drer\tmc4, Drer\tmc8, Drer\tmc2b, Drer\tmc2a, Drer\tmc1, Drer\LOC100149241, Drer\si:dkey-202l16.5" - "Cele\tmc-1, Cele\tmc-2" "Xtro\tmc6, Xtro\tmc2" "Mmus\Tmc1, Mmus\Tmc6, Mmus\Tmc5, Mmus\Tmc7, Mmus\Tmc3, Mmus\Tmc8, Mmus\Tmc4, Mmus\Tmc2" "Hsap\TMC8, Hsap\TMC2, Hsap\TMC4, Hsap\TMC1, Hsap\TMC7, Hsap\TMC5, Hsap\TMC3, Hsap\TMC6" FBgn0029067 Dd Dullard http://flybase.org/reports/FBgn0029067 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with UniProtKB:O95476 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with HGNC:19085 phosphoprotein phosphatase activity ; GO:0004721 | inferred from biological aspect of ancestor with PANTHER:PTN000258719 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:19085 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with UniProtKB:O95476 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype positive regulation of triglyceride biosynthetic process ; GO:0010867 | inferred from sequence or structural similarity with UniProtKB:O95476 negative regulation of BMP signaling pathway ; GO:0030514 | inferred from mutant phenotype inferred from genetic interaction with dpp inferred from genetic interaction with put inferred from genetic interaction with sax inferred from genetic interaction with tkv inferred from genetic interaction with Mad inferred from genetic interaction with Dad nuclear envelope organization ; GO:0006998 | inferred from sequence or structural similarity with UniProtKB:O95476 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:O95476 nuclear envelope ; GO:0005635 | inferred from sequence or structural similarity with UniProtKB:O95476 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with UniProtKB:O95476 Nem1-Spo7 phosphatase complex ; GO:0071595 | inferred from sequence or structural similarity with UniProtKB:O95476 Nem1-Spo7 phosphatase complex ; GO:0071595 | inferred from sequence or structural similarity with HGNC:19085 nuclear membrane ; GO:0031965 | inferred from sequence or structural similarity with UniProtKB:O95476 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:19085 "CG1696, BcDNA:LD08201, anon-WO03040301.167, l(1)G0269, Dd, ddd, 20151539" "IPR004274:FCP1 homology domain, IPR011948:Dullard phosphatase domain, eukaryotic, IPR023214:HAD-like domain" CG1696 11-Aug-17 DroID_v2017_08 "Drer\ctdsplb, Drer\ctdnep1b, Drer\ctdspla, Drer\ctdspl2b, Drer\ctdspl3, Drer\ctdsp2, Drer\ctdspl2a, Drer\ctdsp1, Drer\ublcp1, Drer\ctdnep1a" "Scer\PSR1, Scer\NEM1, Scer\PSR2" Cele\cnep-1 "Xtro\ctdnep1, Xtro\ctdsp2, Xtro\ctdspl2, Xtro\ublcp1, Xtro\ctdspl, Xtro\ctdsp1" "Mmus\Ctdsp1, Mmus\Ublcp1, Mmus\Ctdspl2, Mmus\Ctdspl, Mmus\Ctdsp2, Mmus\Ctdnep1" "Hsap\CTDNEP1, Hsap\CTDSPL2, Hsap\CTDSPL, Hsap\CTDSP1, Hsap\CTDSP2, Hsap\UBLCP1" "partially lethal - majority die,recessive,lethal,viable" "wing,anterior crossvein,ectopic,posterior crossvein,wing vein L2,wing vein L3,heat sensitive,wing vein L4,wing vein L5,endoplasmic reticulumen-e16E,lipid particleen-e16E,wing vein" FBgn0025635 CG17829 - http://flybase.org/reports/FBgn0025635 FBgn0029530 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "EG:115C2.6, CG17829" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG17829 11-Aug-17 DroID_v2017_08 "Drer\hinfp, Drer\zgc:112083, Drer\rps6" Scer\ZAP1 "Cele\rps-6, Cele\hinf-1" "Xtro\rps6, Xtro\hinfp" "Mmus\Rps6, Mmus\Hinfp" "Hsap\HINFP, Hsap\RPS6" viable DRSC18484 I 1.924853291 0.10449954 0.145089788 0.098309319 -0.333545429 1.047433407 FBgn0013995 Calx Na/Ca-exchange protein http://flybase.org/reports/FBgn0013995 FBgn0020315 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from direct assay calcium:sodium antiporter activity ; GO:0005432 | inferred from direct assay calcium:sodium antiporter activity ; GO:0005432 | traceable author statement calcium:sodium antiporter activity ; GO:0005432 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from electronic annotation with InterPro:IPR004836 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 phototransduction ; GO:0007602 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype neuromuscular process controlling posture ; GO:0050884 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR003644, InterPro:IPR004837" "CG5685, NCX, CALX1.1, Ncx, Dmel/Ncx, 9C5, anon-93ABa, Calx, calX, calx, CalX, CALX" "IPR003644:Na-Ca exchanger/integrin-beta4, IPR004836:Sodium/calcium exchanger protein, IPR004837:Sodium/calcium exchanger membrane region, IPR032452:Sodium/calcium exchanger domain, C-terminal extension" CG5685 11-Aug-17 DroID_v2017_08 "Drer\slc8a3, Drer\slc8a2b, Drer\slc8a4a, Drer\frem2a, Drer\slc8a4b, Drer\adgrv1, Drer\slc8a1a, Drer\fras1, Drer\slc8a1b, Drer\frem3, Drer\frem2b, Drer\slc8a2a" - "Cele\ncx-2, Cele\ncx-3, Cele\ncx-1" "Xtro\adgrv1, Xtro\slc8a2, Xtro\slc8a3, Xtro\fras1, Xtro\frem3, Xtro\slc8a1" "Mmus\Slc8a1, Mmus\Frem3, Mmus\Fras1, Mmus\Slc8a3, Mmus\Adgrv1, Mmus\Slc8a2, Mmus\Frem2" "Hsap\FRAS1, Hsap\SLC8A1, Hsap\SLC8A3, Hsap\FREM3, Hsap\ADGRV1, Hsap\SLC8A2, Hsap\FREM2" " adult stage , embryonic stage " " adult head

, optic nerve

,

ubiquitous , adult brain

, retina

" "neurophysiology defective,viable,neuroanatomy defective" "eye,eye photoreceptor cell,rhabdomere" DRSC21850 E 0.785693573 -0.145199557 2.092255596 0.906851185 0.201197369 -0.065564438 FBgn0086356 tum tumbleweed http://flybase.org/reports/FBgn0086356 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with SGD:S000000464 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from biological aspect of ancestor with PANTHER:PTN000571279 neuron development ; GO:0048666 | inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype inferred from genetic interaction with arm inferred from genetic interaction with pav neurogenesis ; GO:0022008 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype inferred from genetic interaction with nkd inferred from genetic interaction with Axn cell proliferation ; GO:0008283 | inferred from genetic interaction with Cdc42 regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype Rho protein signal transduction ; GO:0007266 | inferred from genetic interaction with vn inferred from genetic interaction with aos inferred from genetic interaction with rho inferred from genetic interaction with Pak somatic muscle development ; GO:0007525 | inferred from mutant phenotype regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from mutant phenotype maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype cell fate determination ; GO:0001709 | inferred from mutant phenotype regulation of cytokinesis ; GO:0032465 | inferred from mutant phenotype cellular protein localization ; GO:0034613 | inferred from mutant phenotype perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay spindle ; GO:0005819 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay midbody ; GO:0030496 | colocalizes_with inferred from direct assay cortical microtubule ; GO:0055028 | colocalizes_with inferred from direct assay "tum, AcGAP, CG13345, racGAP50C, RacGap50C, 13345, i249, acGAP, RacGAP, eon, RhoGAP-50C14, DRacGAP, RacGAP50C, RacGAP50c, racGAP50c, racGAP50, RacGap, TUM, Tumbleweed" "IPR008936:Rho GTPase activation protein, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR000198:Rho GTPase-activating protein domain" CG13345 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-416j23.1, Drer\racgap1" "Scer\RGA1, Scer\BEM3, Scer\RGA2, Scer\ECM25, Scer\RGD1" Cele\cyk-4 Xtro\racgap1 Mmus\Racgap1 Hsap\RACGAP1 " , embryonic stage | embryonic cycle 16 " " cell

, organism

" FBgn0030420 CG12717 - http://flybase.org/reports/FBgn0030420 protein_coding_gene SUMO-specific protease activity ; GO:0016929 | inferred from sequence or structural similarity with SGD:S000001293 protein desumoylation ; GO:0016926 | inferred from sequence or structural similarity with SGD:S000001293 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype dendritic spine morphogenesis ; GO:0060997 | inferred from mutant phenotype central nervous system projection neuron axonogenesis ; GO:0021952 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay CG12717 "IPR003653:Ulp1 protease family, C-terminal catalytic domain" CG12717 11-Aug-17 DroID_v2017_08 "Drer\senp2, Drer\senp7b, Drer\senp6a, Drer\si:dkey-100n23.3, Drer\senp6b" Scer\ULP2 "Cele\ulp-5, Cele\ulp-4, Cele\ulp-2" Xtro\senp6 "Mmus\Senp7, Mmus\Senp6" "Hsap\SENP7, Hsap\SENP6" viable DRSC19494 I 1.620592791 -0.573786923 0.221785968 -0.113833208 0.829154151 0.288318323 FBgn0036264 CG11529 - http://flybase.org/reports/FBgn0036264 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "148640_at, SP84, CG11529" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11529 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\si:dkey-78l4.10" - - - "Mmus\Cela3a, Mmus\Cela1, Mmus\Ctrb1, Mmus\Ctrl, Mmus\Cela3b, Mmus\Cela2a, Mmus\Ctrc" - "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" FBgn0033468 CG1418 - http://flybase.org/reports/FBgn0033468 protein_coding_gene - - - CG1418 IPR004895:Prenylated rab acceptor PRA1 CG1418 11-Aug-17 DroID_v2017_08 Drer\rabac1 Scer\YIP3 - Xtro\rabac1 Mmus\Rabac1 Hsap\RABAC1 viable FBgn0015618 Cdk8 Cyclin-dependent kinase 8 http://flybase.org/reports/FBgn0015618 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KTX8 inferred from physical interaction with UniProtKB:Q9VW47" imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype snRNA 3'-end processing ; GO:0034472 | inferred from direct assay chaeta development ; GO:0022416 | inferred from mutant phenotype G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from mutant phenotype sex comb development ; GO:0045498 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay axon guidance ; GO:0007411 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement "mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from physical interaction with kto, skd, CycC" "Cdk8, cdk8, CDK8, p58, CG10572, dTRAP56, DmCdk8, dCdk8" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG10572 11-Aug-17 DroID_v2017_08 "Drer\cdk8, Drer\cdk19" "Scer\SSN3, Scer\KDX1" Cele\cdk-8 "Xtro\cdk8, Xtro\cdk19" "Mmus\Cdk8, Mmus\Cdk19" "Hsap\CDK19, Hsap\CDK8" "neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,recessive,some die during third instar larval stage,viable,visible" "leg,somatic clone - Minute background,sex comb tooth,somatic clone,prothoracic tarsal segment,mesothoracic bristle,mesothoracic tergum" DRSC11113 K -0.414466901 1.103892674 -1.083086244 -0.286429485 1.341834692 2.509891507 FBgn0026376 Rgl Ral guanine nucleotide dissociation stimulator-like http://flybase.org/reports/FBgn0026376 FBgn0036385 protein_coding_gene "Ral guanyl-nucleotide exchange factor activity ; GO:0008321 | inferred from genetic interaction with Rala Ras GTPase binding ; GO:0017016 | inferred from physical interaction with Ras85D, Ras64B, Rap1" "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001895, InterPro:IPR019804 activation of GTPase activity ; GO:0090630 | inferred from genetic interaction with Rala regulation of Ras protein signal transduction ; GO:0046578 | inferred by curator from GO:0008321" cellular_component ; GO:0005575 | no biological data available "CG8865, DRgl, RalGDS, dRGL, Rgl, rgl, RasGDS" "IPR000159:Ras-associating (RA) domain, IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR019804:Ras guanine-nucleotide exchange factor, conserved site, IPR023578:Ras guanine nucleotide exchange factor domain, IPR029071:Ubiquitin-related domain" CG8865 11-Aug-17 DroID_v2017_08 "Drer\rgl2, Drer\rgl1, Drer\rgl3a, Drer\si:ch211-251j10.3" Scer\CDC25 Cele\rgl-1 "Xtro\ralgds, Xtro\zbtb22, Xtro\rgl3" "Mmus\1700123K08Rik, Mmus\Rgl1, Mmus\Gm3415, Mmus\Gm6408, Mmus\Rgl2, Mmus\Gm6309, Mmus\Gm3404, Mmus\4933421I07Rik, Mmus\4930474N05Rik, Mmus\Ralgds, Mmus\Gm3402, Mmus\4930449I24Rik, Mmus\4930596D02Rik, Mmus\1700001J03Rik, Mmus\Gm6370, Mmus\Rgl3" "Hsap\RGL1, Hsap\RGL3, Hsap\RGL4, Hsap\RALGDS, Hsap\RGL2" "viable,fertile,visible,lethal" "tormogen cell,eye,ommatidium,wing,wing vein,macrochaeta" FBgn0038680 Cyp12a5 Cyp12a5 http://flybase.org/reports/FBgn0038680 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "Cyp12a5, 12a5, CG11821, CYP12a5" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG11821 11-Aug-17 DroID_v2017_08 "Drer\cyp27b1, Drer\si:dkey-91i10.3, Drer\cyp27a1.4, Drer\cyp11c1, Drer\cyp27a7, Drer\cyp27a1.2, Drer\si:ch211-113j14.1, Drer\cyp27c1, Drer\zgc:136333, Drer\cyp11a2, Drer\cyp24a1" Scer\DIT2 "Cele\cyp-44A1, Cele\ZK177.4, Cele\cyp-37B1" "Xtro\cyp27c1, Xtro\cyp11a1, Xtro\cyp27a1, Xtro\cyp24a1, Xtro\LOC100145331, Xtro\cyp27b1" "Mmus\Cyp27a1, Mmus\Cyp11a1, Mmus\Cyp27b1, Mmus\Cyp11b1, Mmus\Cyp11b2, Mmus\Cyp24a1" "Hsap\CYP24A1, Hsap\CYP11B1, Hsap\CYP27A1, Hsap\CYP11A1, Hsap\CYP11B2, Hsap\CYP27C1, Hsap\CYP27B1" viable FBgn0028863 CG4587 - http://flybase.org/reports/FBgn0028863 protein_coding_gene voltage-gated calcium channel activity ; GO:0005245 | inferred from sequence or structural similarity - - "DS07108.2, BG:DS07108.2, CG4587, mdcds_3066" "IPR002035:von Willebrand factor, type A, IPR013608:VWA N-terminal, IPR013680:Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region, IPR033479:Double Cache domain 1" CG4587 11-Aug-17 DroID_v2017_08 "Drer\cachd1, Drer\cacna2d2a, Drer\cacna2d4b, Drer\cacna2d4a, Drer\cacna2d2b, Drer\cacna2d3, Drer\cacna2d1a" - "Cele\tag-180, Cele\unc-36" "Xtro\cacna2d1, Xtro\cacna2d2, Xtro\cacna2d4, Xtro\cachd1" "Mmus\Cachd1, Mmus\Cacna2d2, Mmus\Cacna2d4, Mmus\Cacna2d3, Mmus\Cacna2d1" "Hsap\CACNA2D2, Hsap\CACNA2D1, Hsap\CACNA2D3, Hsap\CACNA2D4, Hsap\CACHD1" "partially lethal - majority die,some die during pupal stage,viable" FBgn0032395 CG6734 - http://flybase.org/reports/FBgn0032395 protein_coding_gene - - - "CG6734, cg6734" "IPR000409:BEACH domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG6734 11-Aug-17 DroID_v2017_08 "Drer\wdfy4, Drer\wdfy3, Drer\nbeab, Drer\lrba, Drer\nbeaa, Drer\wdr81, Drer\nsmaf" Scer\BPH1 Cele\sorf-2 "Xtro\wdfy3, Xtro\nsmaf, Xtro\wdr81, Xtro\lyst" "Mmus\Nsmaf, Mmus\Wdfy4, Mmus\Lyst, Mmus\Lrba, Mmus\Nbea, Mmus\Wdr81, Mmus\Wdfy3" "Hsap\LYST, Hsap\WDR81, Hsap\WDFY3, Hsap\NBEA, Hsap\WDFY4, Hsap\NSMAF, Hsap\LRBA" FBgn0032200 CG5676 - http://flybase.org/reports/FBgn0032200 protein_coding_gene - mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000482219 integral component of mitochondrial outer membrane ; GO:0031307 | inferred from biological aspect of ancestor with PANTHER:PTN000482219 "LD31953, BEST:LD31953, CG5676" IPR007014:FUN14 CG5676 11-Aug-17 DroID_v2017_08 "Drer\fundc2, Drer\fundc1" Scer\FUN14 Cele\T06D8.7 Xtro\fundc1 "Mmus\Fundc1, Mmus\Fundc2" "Hsap\FUNDC1, Hsap\FUNDC2" "partially lethal - majority die,some die during pupal stage" FBgn0035866 Arl5 ADP-ribosylation factor-like 5 http://flybase.org/reports/FBgn0035866 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006689, InterPro:IPR024156 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000002351" "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 protein targeting to Golgi ; GO:0000042 | inferred from mutant phenotype retrograde transport, endosome to Golgi ; GO:0042147 | inferred from mutant phenotype" trans-Golgi network ; GO:0005802 | inferred from direct assay "CG7197, Q9VSG8, Arl5" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024156:Small GTPase superfamily, ARF type" CG7197 11-Aug-17 DroID_v2017_08 "Drer\arl5c, Drer\arl6, Drer\si:ch1073-165f9.2, Drer\trim23, Drer\arf2a, Drer\arf3b, Drer\arl14, Drer\zgc:110286, Drer\arl4d, Drer\arl4aa, Drer\arl5a, Drer\arl4ca, Drer\arf4a, Drer\arl8, Drer\arf1, Drer\arl11, Drer\arl9, Drer\arf3a, Drer\arl4ab, Drer\arf5, Drer\arl4cb, Drer\zgc:77650" "Scer\ARF1, Scer\ARF3, Scer\ARF2" Cele\arl-5 "Xtro\arl4a, Xtro\arl11, Xtro\arl6, Xtro\arf4, Xtro\arl9, Xtro\arl11, Xtro\arf1, Xtro\arl14, Xtro\arl5b, Xtro\arf3, Xtro\arf5, Xtro\arl5c, Xtro\arl4c, Xtro\trim23, Xtro\arl5a" "Mmus\Arl4c, Mmus\Arl5c, Mmus\Arl4a, Mmus\Arl9, Mmus\Arl5b, Mmus\Arl5a, Mmus\Arl4d, Mmus\Arf2, Mmus\Arf1, Mmus\Arl6, Mmus\Arf3, Mmus\Trim23, Mmus\Arf5, Mmus\Arf4, Mmus\Arl11" "Hsap\ARL4A, Hsap\ARL4D, Hsap\ARL5B, Hsap\ARL6, Hsap\ARL5A, Hsap\ARL5C, Hsap\ARF4, Hsap\ARF1, Hsap\ARF3, Hsap\TRIM23, Hsap\ARL17B, Hsap\ARL9, Hsap\ARL11, Hsap\ARL14, Hsap\ARF5, Hsap\ARL4C" viable FBgn0002023 Lim3 Lim3 http://flybase.org/reports/FBgn0002023 FBgn0032756 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 regulation of cell cycle ; GO:0051726 | inferred from direct assay motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype nervous system development ; GO:0007399 | traceable author statement" - "Lim3, lim3, CG10699, l(2)37Bd, l(2)Bd, CG15174, Lim-3A" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001781:Zinc finger, LIM-type, IPR009057:Homeobox domain-like" CG10699 11-Aug-17 DroID_v2017_08 "Drer\lhx1a, Drer\lhx5, Drer\lhx3, Drer\lhx4" - "Cele\lin-11, Cele\ceh-14" "Xtro\lhx5, Xtro\lhx1, Xtro\lhx3" "Mmus\Lhx4, Mmus\Lhx1, Mmus\Lhx3, Mmus\Lhx5" "Hsap\LHX4, Hsap\LHX3, Hsap\LHX1, Hsap\LHX5" " embryonic stage | stage 14 , embryonic stage | stage >=12 , embryonic stage | stage 12 " " embryonic neuron | subset

, embryonic peripheral nervous system | restricted

, RP neuron

, ventral nerve cord | restricted

, embryonic/larval proventriculus

, dorsal vessel primordium

, embryonic brain | restricted

, larval alary muscle | precursor

" "lethal - all die before end of larval stage,recessive,some die during larval stage,short lived,partially lethal - majority die,lethal,neuroanatomy defective,dominant,viable" "cuticle & abdomen & pharate adult,cuticle & thorax & pharate adult,cuticle & head & pharate adult,melanotic mass,transverse nerve,intersegmental nerve,abdominal intersegmental nerve,abdominal segmental nerve" FBgn0263351 AP-2mu "Adaptor Protein complex 2, mu subunit" http://flybase.org/reports/FBgn0263351 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from mutant phenotype "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001392, InterPro:IPR018240 neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle coating ; GO:0016183 | traceable author statement vesicle coating ; GO:0006901 | traceable author statement endocytosis ; GO:0006897 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype" AP-2 adaptor complex ; GO:0030122 | inferred from mutant phenotype coated vesicle ; GO:0030135 | traceable author statement synaptic vesicle ; GO:0008021 | traceable author statement "AP50, AP-50, cg7057, CG7057, mu2, Dmu2, anon-EST:Posey50, anon-WO0172774.104, AP-2mu, MENE(3R)-D, MENE (3R)-D, apm4, AP2mu2, mu2-ada" "IPR001392:Clathrin adaptor, mu subunit, IPR011012:Longin-like domain, IPR018240:Clathrin adaptor, mu subunit, conserved site, IPR022775:AP complex, mu/sigma subunit, IPR028565:Mu homology domain" CG7057 11-Aug-17 DroID_v2017_08 "Drer\ap1m3, Drer\ap5m1, Drer\ap1m1, Drer\ap2m1a, Drer\ap4m1, Drer\ap1m2, Drer\ap2m1b" "Scer\APM1, Scer\APM4, Scer\APM2" "Cele\apm-1, Cele\ZC101.1, Cele\dpy-23" "Xtro\ap1m2, Xtro\ap2m1, Xtro\ap1m1, Xtro\ap5m1, Xtro\ap4m1" "Mmus\Ap1m1, Mmus\Ap4m1, Mmus\Ap1m2, Mmus\Ap5m1, Mmus\Ap2m1" "Hsap\AP2M1, Hsap\AP5M1, Hsap\AP1M2, Hsap\AP1M1, Hsap\AP4M1" " embryonic stage | stage >=13 , embryonic stage | stage >=9 , embryonic stage | stage 13 , embryonic stage -- adult stage " " embryonic central nervous system

, embryonic neuroblast

, gastric caecum

, anterior embryonic/larval midgut

, posterior embryonic/larval midgut

, embryonic/larval midgut

" DRSC14090 IE 0.459302835 1.511244517 0.470415368 1.944734895 -0.778440009 -0.198620924 FBgn0032693 Cyp310a1 Cyp310a1 http://flybase.org/reports/FBgn0032693 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with dsh inferred from genetic interaction with sgg" - "CG10391, anon-EST:CL1d7, Cyp310a, 310a1, H, Cyp310a1, Cyp310, cyp310a1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG10391 11-Aug-17 DroID_v2017_08 "Drer\cyp3c4, Drer\cyp3c1, Drer\cyp3a65, Drer\cyp3c3, Drer\tbxas1, Drer\cyp3c2" - "Cele\cyp-13A11, Cele\cyp-13B1, Cele\cyp-13A4, Cele\cyp-44A1, Cele\cyp-13A8, Cele\cyp-13A6, Cele\cyp-13A12, Cele\cyp-25A1, Cele\cyp-43A1, Cele\cyp-25A2, Cele\cyp-25A3, Cele\cyp-13A2, Cele\cyp-13A10, Cele\cyp-13A1, Cele\cyp-13A5, Cele\cyp-25A4, Cele\cyp-13A3, Cele\cyp-13A7, Cele\cyp-13B2" "Xtro\cyp3a4, Xtro\LOC100494419, Xtro\cyp3a5, Xtro\tbxas1" "Mmus\Cyp3a41b, Mmus\Tbxas1, Mmus\Cyp3a57, Mmus\Cyp3a44, Mmus\Cyp3a13, Mmus\Cyp3a25, Mmus\Cyp3a16, Mmus\Cyp3a41a, Mmus\Cyp3a59, Mmus\Cyp3a11" "Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A43, Hsap\CYP3A5, Hsap\TBXAS1, Hsap\CYP3A7, Hsap\CYP3A4" " embryonic stage | stage >5 , embryonic stage | stage 13 , embryonic stage | stage 5 " " mesoderm

, embryonic/larval fat body

, mesoderm anlage

" FBgn0053843 His1:CG33843 His1:CG33843 http://flybase.org/reports/FBgn0053843 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33843, His1:CG33843" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33843 11-Aug-17 DroID_v2017_08 "Drer\zgc:153405, Drer\si:dkey-108k21.14, Drer\zgc:163061, Drer\si:dkey-108k21.21, Drer\si:ch1073-159d7.7, Drer\histh1l, Drer\si:dkey-108k21.10, Drer\h1f0, Drer\zgc:110216, Drer\zgc:110425, Drer\h1m, Drer\si:ch73-36p18.1, Drer\si:ch211-113a14.24, Drer\si:dkey-261m9.12, Drer\h1fx" Scer\HHO1 "Cele\hil-2, Cele\hil-6, Cele\his-24, Cele\hil-3, Cele\hil-4, Cele\hil-1, Cele\hil-5" - "Mmus\Hist1h1t, Mmus\Hist1h1b, Mmus\H1fnt, Mmus\Hist1h1d, Mmus\Hils1, Mmus\Hist1h1e, Mmus\Hist1h1c, Mmus\Hist1h1a, Mmus\H1fx, Mmus\H1foo" "Hsap\HIST1H1A, Hsap\HIST1H1C, Hsap\HIST1H1D, Hsap\HIST1H1T, Hsap\H1F0, Hsap\HIST1H1E, Hsap\H1FX, Hsap\H1FNT, Hsap\HIST1H1B, Hsap\H1FOO" FBgn0027951 MTA1-like Metastasis associated 1-like http://flybase.org/reports/FBgn0027951 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000679 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000679 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000679 chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR001025" chromosome condensation ; GO:0030261 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay histone deacetylase complex ; GO:0000118 | inferred from direct assay NuRD complex ; GO:0016581 | inferred from direct assay "dMTA, dMTA1-like, CG2244, p120, MTA1-like, MTA1, dMTA-1, MTA-like, MTA" "IPR000679:Zinc finger, GATA-type, IPR000949:ELM2 domain, IPR001005:SANT/Myb domain, IPR001025:Bromo adjacent homology (BAH) domain, IPR009057:Homeobox domain-like, IPR017884:SANT domain, IPR013088:Zinc finger, NHR/GATA-type, IPR013087:Zinc finger C2H2-type" CG2244 11-Aug-17 DroID_v2017_08 "Drer\eml3, Drer\mta2, Drer\eml1, Drer\rerea, Drer\mta3, Drer\mta1, Drer\eml2" - "Cele\lin-40, Cele\egl-27" "Xtro\eml4, Xtro\mta2, Xtro\mta1, Xtro\eml2, Xtro\eml3" "Mmus\Mta1, Mmus\Eml4, Mmus\Mta2, Mmus\Eml1, Mmus\Mta3, Mmus\Eml2, Mmus\Rere, Mmus\Eml3" "Hsap\RERE, Hsap\EML1, Hsap\EML3, Hsap\EML2, Hsap\MTA2, Hsap\MTA3, Hsap\MTA1, Hsap\EML4" "viable,fertile,visible" mesothoracic tergum FBgn0035143 Ppm1 Ppm1 http://flybase.org/reports/FBgn0035143 protein_coding_gene cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR000222 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from electronic annotation with InterPro:IPR015655 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with MGI:MGI:99878 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with MGI:MGI:99878 protein dephosphorylation ; GO:0006470 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "PPM1, PP2C, Ppm1, CG12169, dPPM1" "IPR000222:PPM-type phosphatase, divalent cation binding, IPR001932:PPM-type phosphatase domain, IPR015655:Protein phosphatase 2C family" CG12169 11-Aug-17 DroID_v2017_08 "Drer\ppm1g, Drer\ppm1na, Drer\ppm1bb, Drer\ppm1aa, Drer\ppm1ba, Drer\ppm1nb, Drer\ppm1ab, Drer\ppm1f" "Scer\PTC3, Scer\PTC1, Scer\PTC4, Scer\PTC2" "Cele\F42G9.1, Cele\ppm-1, Cele\fem-2, Cele\ppm-2" "Xtro\ppm1a, Xtro\ppm1b" "Mmus\Ppm1a, Mmus\Ppm1n, Mmus\Ilkap, Mmus\Ppm1e, Mmus\Ppm1g, Mmus\Ppm1f, Mmus\Ppm1b" "Hsap\ILKAP, Hsap\PPM1G, Hsap\PPM1E, Hsap\PPM1N, Hsap\PPM1A, Hsap\PPM1F, Hsap\PPM1B" viable DRSC08260 I 1.75199879 0.905614147 1.383013034 0.908599763 0.882381091 0.626929785 FBgn0025825 HDAC3 Histone deacetylase 3 http://flybase.org/reports/FBgn0025825 FBgn0037331 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with ebi protein binding ; GO:0005515 | inferred from physical interaction with Smyd4-2 histone deacetylase activity ; GO:0004407 | inferred from mutant phenotype histone deacetylase activity ; GO:0004407 | inferred from direct assay "cell growth ; GO:0016049 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay histone deacetylation ; GO:0016575 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype inferred from genetic interaction with HDAC1" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "HDAC3, dmHDA402, HDAC, dHDAC3, DmHDAC3, CG2128, DHDAC3, Hdac3, hdac3, Dromel_CG2128_FBtr0078767_hdac3_mORF, Hdac 3" "IPR000286:Histone deacetylase superfamily, IPR003084:Histone deacetylase, IPR023801:Histone deacetylase domain" CG2128 11-Aug-17 DroID_v2017_08 "Drer\phka1a, Drer\hdac3, Drer\hdac1" "Scer\HOS2, Scer\RPD3, Scer\HOS1" "Cele\hda-3, Cele\hda-2, Cele\hda-1" "Xtro\hdac8, Xtro\hdac1, Xtro\hdac3, Xtro\hdac2" "Mmus\Hdac2, Mmus\Hdac1, Mmus\Hdac3, Mmus\Hdac8" "Hsap\HDAC3, Hsap\HDAC1, Hsap\HDAC2, Hsap\HDAC8" "visible,dominant,neuroanatomy defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell growth,partially lethal,small body,lethal - all die during larval stage,large body,increased cell death" "wing,wing vein,ectopic,projection neuron,somatic clone,eye,ommatidium,embryonic/larval fat body,imaginal disc" FBgn0034065 Rrp42 Rrp42 http://flybase.org/reports/FBgn0034065 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype exosome (RNase complex) ; GO:0000178 | inferred from direct assay nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000002269 inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG8395, dRrp42, anon-EST:Posey187, anon-EST:Posey140, Rrp42" "IPR015847:Exoribonuclease, phosphorolytic domain 2, IPR001247:Exoribonuclease, phosphorolytic domain 1, IPR027408:PNPase/RNase PH domain, IPR020568:Ribosomal protein S5 domain 2-type fold" CG8395 11-Aug-17 DroID_v2017_08 Drer\exosc7 "Scer\RRP45, Scer\RRP42" Cele\exos-7 Xtro\exosc7 Mmus\Exosc7 Hsap\EXOSC7 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0266757 mfr misfire http://flybase.org/reports/FBgn0266757 protein_coding_gene - egg activation ; GO:0007343 | inferred from mutant phenotype sperm plasma membrane disassembly ; GO:0035045 | inferred from mutant phenotype regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype sperm capacitation ; GO:0048240 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype fertilization ; GO:0009566 | inferred from mutant phenotype synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity "CG5747, mfr, Otoferlin" "IPR000008:C2 domain, IPR032362:Ferlin, C-terminal domain, IPR012968:FerIin domain" CG5747 11-Aug-17 DroID_v2017_08 "Drer\myofl, Drer\otofa, Drer\fer1l6, Drer\fer1l4, Drer\myof, Drer\dysf, Drer\otofb" - "Cele\ferl-1, Cele\fer-1" "Xtro\myof, Xtro\fer1l6, Xtro\otof, Xtro\fer1l4" "Mmus\Otof, Mmus\Fer1l5, Mmus\Myof, Mmus\Dysf, Mmus\Fer1l4, Mmus\Fer1l6" "Hsap\FER1L5, Hsap\DYSF, Hsap\FER1L6, Hsap\MYOF, Hsap\OTOF" FBgn0039821 CG15556 - http://flybase.org/reports/FBgn0039821 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000832 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000832 cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000832 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "anon-WO0170980.179, anon-WO0170980.178, CG15556, AT07595p" "IPR000832:GPCR, family 2, secretin-like, IPR017981:GPCR, family 2-like" CG15556 11-Aug-17 DroID_v2017_08 "Drer\adgrf8, Drer\LOC100535070, Drer\adgrl2a, Drer\fbn2b, Drer\adgrf6, Drer\adgrg6, Drer\LOC101884341, Drer\adgre10, Drer\adgrg2a, Drer\adgrl3.1, Drer\adgrf11, Drer\adgrf3b, Drer\adgrl4, Drer\adgre5b.3, Drer\fbn2a, Drer\adgrg3, Drer\adgrg4a, Drer\LOC100538279, Drer\adgrd2, Drer\LOC101886975, Drer\adgre14, Drer\adgrb3, Drer\adgrb2, Drer\adgrf3a, Drer\adgrg11, Drer\adgrb1a, Drer\LOC100537181, Drer\adgrl1a, Drer\adgrg1" - Cele\lat-2 "Xtro\adgrg1, Xtro\adgrl1, Xtro\adgre5, Xtro\adgrv1, Xtro\adgrd1, Xtro\adgrf3, Xtro\adgrf1" "Mmus\Adgrg4, Mmus\Adgrf4, Mmus\Adgrg5, Mmus\Adgrb3, Mmus\Adgrg6, Mmus\Adgrf2, Mmus\Adgre1, Mmus\Adgrf3, Mmus\Adgrg2, Mmus\Adgrd1, Mmus\Adgrf1, Mmus\Adgrb1, Mmus\Adgrg3, Mmus\Adgrf5, Mmus\Adgrg1, Mmus\Adgrg7, Mmus\Adgrl3, Mmus\Adgre5, Mmus\Adgre4, Mmus\Adgrb2, Mmus\Adgrl2, Mmus\Adgrl4, Mmus\Adgrl1" "Hsap\ADGRG2, Hsap\ADGRF4, Hsap\ADGRE1, Hsap\ADGRF1, Hsap\ADGRG4, Hsap\ADGRB3, Hsap\ADGRG7, Hsap\ADGRL4, Hsap\ADGRG3, Hsap\ADGRG6, Hsap\ADGRL3, Hsap\ADGRL2, Hsap\ADGRF3, Hsap\ADGRL1, Hsap\ADGRE3, Hsap\ADGRB2, Hsap\ADGRF2, Hsap\ADGRD2, Hsap\ADGRB1, Hsap\ADGRF5, Hsap\ADGRG5, Hsap\ADGRE5, Hsap\ADGRE2, Hsap\ADGRG1, Hsap\FBN3, Hsap\ADGRD1" "viable,fertile" DRSC15094 I 0.181237638 4.149544708 -0.474086385 0.493464759 0.371373885 1.120189009 FBgn0261794 kcc kazachoc http://flybase.org/reports/FBgn0261794 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 potassium ion symporter activity ; GO:0022820 | inferred from biological aspect of ancestor with PANTHER:PTN000930406 potassium:chloride symporter activity ; GO:0015379 | inferred from biological aspect of ancestor with PANTHER:PTN000930406 potassium:chloride symporter activity ; GO:0015379 | inferred from direct assay cellular hypotonic salinity response ; GO:0071477 | inferred from electronic annotation with InterPro:IPR030364 chloride transmembrane transport ; GO:1902476 | inferred from electronic annotation with InterPro:IPR030364 response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from biological aspect of ancestor with PANTHER:PTN000930408 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR030364 neuronal cell body ; GO:0043025 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "kcc, CG5594, l(2)60A-C, BEST:CK01510, CK01510, CG2768, E(sda)J, Line J, KCC, mdcds_17605, Kcc" "IPR030364:K/Cl co-transporter 3, IPR000076:K/Cl co-transporter, IPR004841:Amino acid permease/ SLC12A domain, IPR004842:SLC12A transporter family, IPR018491:SLC12A transporter, C-terminal" CG5594 11-Aug-17 DroID_v2017_08 "Drer\slc12a7b, Drer\slc12a7a, Drer\si:cabz01102082.1, Drer\si:cabz01090193.1, Drer\si:ch211-59d13.2, Drer\slc12a5b, Drer\slc12a4" Scer\VHC1 "Cele\kcc-2, Cele\kcc-1, Cele\kcc-3" "Xtro\slc12a4, Xtro\slc12a6" "Mmus\Slc12a7, Mmus\Slc12a4, Mmus\Slc12a5, Mmus\Slc12a6" "Hsap\SLC12A4, Hsap\SLC12A7, Hsap\SLC12A6, Hsap\SLC12A5" FBgn0011834 Ser6 Serine protease 6 http://flybase.org/reports/FBgn0011834 - protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP47, CG2071, Ser6" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG2071 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-21e2.3, Drer\gzm3, Drer\si:dkey-16l2.17, Drer\si:ch211-165b19.8, Drer\gzmk, Drer\zgc:92313, Drer\si:dkey-78l4.4, Drer\si:dkeyp-93a5.3, Drer\LOC100004427, Drer\zgc:163079, Drer\si:ch211-165b19.5, Drer\zgc:165423, Drer\ovch1, Drer\si:dkey-21e2.16, Drer\cfd, Drer\gzma, Drer\LOC558805, Drer\si:ch211-165b19.9" - "Cele\try-1, Cele\svh-1, Cele\try-6" - "Mmus\Prss55, Mmus\Klk9, Mmus\Klk14, Mmus\Egfbp2, Mmus\Plg, Mmus\Klk15, Mmus\Gzmk" "Hsap\TPSD1, Hsap\KLK9, Hsap\KLK14, Hsap\GZMA, Hsap\KLK15, Hsap\CFD" viable FBgn0064126 CG33722 - http://flybase.org/reports/FBgn0064126 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31188, CG18238, CG31188-ORFA, CG33722" "IPR001012:UBX domain, IPR029071:Ubiquitin-related domain, IPR021569:TUG ubiquitin-like domain" CG33722 11-Aug-17 DroID_v2017_08 "Drer\aspscr1, Drer\ubxn6" Scer\UBX4 "Cele\ubxn-6, Cele\B0024.10" "Xtro\aspscr1, Xtro\ubxn6" "Mmus\Ubxn6, Mmus\Aspscr1" "Hsap\UBXN6, Hsap\ASPSCR1" "viable,fertile" FBgn0035665 Jon65Aiii Jonah 65Aiii http://flybase.org/reports/FBgn0035665 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 endopeptidase activity ; GO:0004175 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG6483, Jon65A, SP98, anon-EST:GressD16, anon-WO0140519.59, Jon65Aiii, jon65Aiii, Jon65" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG6483 11-Aug-17 DroID_v2017_08 "Drer\zgc:92041, Drer\zgc:92745, Drer\zgc:112368, Drer\ela3l, Drer\zgc:112285, Drer\si:dkey-78l4.10, Drer\zgc:112302" - Cele\svh-1 - "Mmus\Ctrc, Mmus\Ctrb1, Mmus\Cela3b, Mmus\C1s1, Mmus\Cela1, Mmus\Cela2a, Mmus\C1s2, Mmus\Cela3a, Mmus\Ctrl" Hsap\CTRB1 viable FBgn0051632 sens-2 senseless-2 http://flybase.org/reports/FBgn0051632 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG31632, D.m Sens-2, CG17373, CG11243, sens2, sens-2, Sens-2" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31632 11-Aug-17 DroID_v2017_08 "Drer\gfi1b, Drer\gfi1aa, Drer\gfi1ab, Drer\prdm12b" - "Cele\pag-3, Cele\K11D2.4" "Xtro\gfi1b, Xtro\gfi1" "Mmus\Gfi1, Mmus\Zscan4f, Mmus\Zscan4d, Mmus\Prdm12, Mmus\Zscan4b, Mmus\Gfi1b, Mmus\Zscan4c" "Hsap\ZSCAN5A, Hsap\GFI1, Hsap\ZKSCAN2, Hsap\ZSCAN5B, Hsap\ZSCAN9, Hsap\PRDM12, Hsap\ZNF165, Hsap\GFI1B, Hsap\ZNF683" "viable,visible" trichogen cell FBgn0038546 CG7379 - http://flybase.org/reports/FBgn0038546 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 - Sin3-type complex ; GO:0070822 | inferred from direct assay "CG7379, ING1" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR024610:Inhibitor of growth protein, N-terminal histone-binding, IPR028651:ING family, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7379 11-Aug-17 DroID_v2017_08 "Drer\ing2, Drer\ing4, Drer\ing5b, Drer\ing5a, Drer\taf3, Drer\ing3, Drer\ing1" "Scer\PHO23, Scer\YNG2, Scer\YNG1" "Cele\ing-3, Cele\Y43H11AL.1, Cele\lsy-13" "Xtro\ing1, Xtro\taf3, Xtro\ing3, Xtro\ing5, Xtro\ing2" "Mmus\Ing4, Mmus\Ing3, Mmus\Taf3, Mmus\Ing2, Mmus\Ing5, Mmus\Ing1" "Hsap\ING4, Hsap\ING2, Hsap\ING5, Hsap\ING3, Hsap\ING1, Hsap\TAF3" "viable,visible" trichogen cell DRSC24324 K -0.474283439 0.088260455 -0.048829438 0.252400351 0.125861456 2.318656804 FBgn0035640 mad2 mad2 http://flybase.org/reports/FBgn0035640 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z8P9 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from direct assay mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype male germ-line stem cell asymmetric division ; GO:0048133 | inferred from genetic interaction with Mtor regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype regulation of mitotic spindle assembly ; GO:1901673 | inferred from genetic interaction with SAK regulation of mitotic cell cycle spindle assembly checkpoint ; GO:0090266 | inferred from mutant phenotype regulation of mitotic spindle assembly ; GO:1901673 | inferred from mutant phenotype mitotic spindle ; GO:0072686 | colocalizes_with inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay nuclear pore ; GO:0005643 | colocalizes_with inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay spindle pole ; GO:0000922 | colocalizes_with inferred from direct assay spindle matrix ; GO:1990047 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay "mad2, CG17498, Mad2, MAD2" "IPR003511:HORMA domain, IPR027097:Mitotic spindle checkpoint protein Mad2" CG17498 11-Aug-17 DroID_v2017_08 Drer\mad2l1 Scer\MAD2 Cele\mdf-2 Xtro\mad2l1 Mmus\Mad2l1 Hsap\MAD2L1 "mitotic cell cycle defective,developmental rate defective,viable,fertile,cell cycle defective,lethal" embryonic/larval brain FBgn0033289 CG2121 - http://flybase.org/reports/FBgn0033289 protein_coding_gene potassium channel regulator activity ; GO:0015459 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 regulation of potassium ion transport ; GO:0043266 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 skeletal muscle contraction ; GO:0003009 | inferred from mutant phenotype regulation of muscle contraction ; GO:0006937 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 striated muscle dense body ; GO:0055120 | inferred from biological aspect of ancestor with PANTHER:PTN000455664 "CG8698, CG2121" "IPR020846:Major facilitator superfamily domain, IPR010291:Ion channel regulatory protein, UNC-93" CG2121 11-Aug-17 DroID_v2017_08 "Drer\unc93a, Drer\unc93b1" - Cele\unc-93 "Xtro\unc93a, Xtro\unc93b1" "Mmus\Unc93b1, Mmus\Gm9992, Mmus\Unc93a" "Hsap\UNC93B1, Hsap\UNC93A" viable FBgn0039828 CG1542 - http://flybase.org/reports/FBgn0039828 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:15531 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000315113 rRNA processing ; GO:0006364 | inferred from sequence or structural similarity with SGD:S000001655 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000315113 "nuclear periphery ; GO:0034399 | inferred from biological aspect of ancestor with PANTHER:PTN000315113 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000315113 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with HGNC:15531 inferred from sequence or structural similarity with SGD:S000001655 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000315113" "CG1542, EBP2" IPR008610:Eukaryotic rRNA processing CG1542 11-Aug-17 DroID_v2017_08 Drer\ebna1bp2 Scer\EBP2 Cele\C18A3.3 Xtro\ebna1bp2 Mmus\Ebna1bp2 Hsap\EBNA1BP2 "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0259483 Mob4 MOB kinase activator 4 http://flybase.org/reports/FBgn0259483 protein_coding_gene "protein kinase binding ; GO:0019901 | inferred from sequence or structural similarity with mats, Mob4" negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype terminal bouton ; GO:0043195 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "Mob4, dmob4, DMob4, Dmob4, CG3403, MOB4" IPR005301:MOB kinase activator family CG3403 11-Aug-17 DroID_v2017_08 Drer\mob4 Scer\MOB1 Cele\C30A5.3 Xtro\mob4 Mmus\Mob4 "Hsap\MOB4, Hsap\HSPE1-MOB4" FBgn0000339 cni cornichon http://flybase.org/reports/FBgn0000339 FBgn0020601 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P42287 vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | non-traceable author statement dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype gurken signaling pathway ; GO:0008314 | traceable author statement intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification ; GO:0030722 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR003377 endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay "BG:DS02740.13, IV, spnG, anon-35Fe, CG5855, cni, Cni" "IPR003377:Cornichon, IPR033466:Cornichon, conserved site" CG5855 11-Aug-17 DroID_v2017_08 "Drer\cnih3, Drer\cnih2, Drer\cnih4, Drer\cnih1" "Scer\ERV14, Scer\ERV15" Cele\cni-1 "Xtro\cnih1, Xtro\cnih2, Xtro\cnih4" "Mmus\Cnih3, Mmus\Cnih4, Mmus\Cnih1, Mmus\Cnih2" "Hsap\CNIH1, Hsap\CNIH4, Hsap\CNIH3, Hsap\CNIH2" " oogenesis stage | stage S1-7 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S10 " " germarium

, nurse cell

" "wild-type,lethal,maternal effect,partially lethal - majority die,dorsal/ventral axis specification defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable" "oocyte nucleus,egg,dorsal appendage,mesoderm,egg chamber,embryonic epidermis,oocyte,chorion,ectopic,micropyle,maternal effect,eye,ommatidium,interommatidial bristle,ocellar bristle,postvertical bristle,wing vein,wing vein L2" FBgn0011747 Ank Ankyrin http://flybase.org/reports/FBgn0011747 - protein_coding_gene cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity spectrin binding ; GO:0030507 | inferred from biological aspect of ancestor with PANTHER:PTN001537955 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000488 protein targeting to plasma membrane ; GO:0072661 | inferred from biological aspect of ancestor with PANTHER:PTN001537955 cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay fusome ; GO:0045169 | NOT inferred from direct assay spectrosome ; GO:0045170 | inferred from direct assay "CG1651, ank, ANK, Dank1, CG32008, Ank, dank1, DAnk1" "IPR000488:Death domain, IPR000906:ZU5 domain, IPR002110:Ankyrin repeat, IPR011029:Death-like domain, IPR020683:Ankyrin repeat-containing domain, IPR030301:Ankyrin-B" CG1651 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-86e18.2, Drer\ankef1a, Drer\ankrd28b, Drer\ank1a, Drer\ank1b, Drer\tnksa, Drer\ank2b, Drer\ank2a, Drer\trpn1, Drer\ankdd1a, Drer\pidd1, Drer\si:ch211-203b8.6, Drer\ankrd52b, Drer\si:ch73-193i2.2, Drer\ankrd1b, Drer\ankk1, Drer\ank3a, Drer\ankdd1b, Drer\ank3b, Drer\ankef1b, Drer\hace1, Drer\tnksb, Drer\ankrd52a, Drer\ankrd44" Scer\YGL242C "Cele\trp-4, Cele\F22G12.4, Cele\unc-44" "Xtro\LOC100492885, Xtro\ank1, Xtro\ankdd1a, Xtro\hace1, Xtro\ankk1, Xtro\ankef1, Xtro\ank3, Xtro\tnks2, Xtro\cat2, Xtro\ank2, Xtro\asb7" "Mmus\Hace1, Mmus\Ankrd44, Mmus\Ankrd61, Mmus\Pidd1, Mmus\Tnks2, Mmus\Ankdd1a, Mmus\Ankrd28, Mmus\Asb7, Mmus\Ankmy1, Mmus\Ankrd65, Mmus\Ankef1, Mmus\Rnasel, Mmus\Ank3, Mmus\Ankrd52, Mmus\Ankrd60, Mmus\Ank1, Mmus\Ankk1, Mmus\Ankrd53, Mmus\Ank2, Mmus\Ankrd42, Mmus\Ankdd1b, Mmus\Tnks" "Hsap\ANKMY1, Hsap\ANKRD60, Hsap\ASB7, Hsap\TNKS, Hsap\ANK3, Hsap\ANKRD28, Hsap\ANKK1, Hsap\ANKRD52, Hsap\ANK1, Hsap\RNASEL, Hsap\DTHD1, Hsap\ANK2, Hsap\PIDD1, Hsap\ANKRD65, Hsap\TNKS2, Hsap\ANKEF1, Hsap\HACE1, Hsap\ANKRD44, Hsap\ANKDD1A, Hsap\ANKRD53, Hsap\ANKRD61, Hsap\ANKDD1B" " embryonic stage , oogenesis stage && adult stage | female " ovary

" adult stage && oogenesis stage | early , adult stage && oogenesis stage , larval stage , embryonic stage&&larval stage&&adult stage " " spectrosome &&of germline stem cell

, follicle cell

,salivary gland

" viable FBgn0017566 ND-75 NADH dehydrogenase (ubiquinone) 75 kDa subunit http://flybase.org/reports/FBgn0017566 - protein_coding_gene "iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR001041, InterPro:IPR010228, InterPro:IPR015405 electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001041 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P28331 NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | contributes_to inferred from sequence or structural similarity with HGNC:7707" ATP synthesis coupled electron transport ; GO:0042773 | inferred from electronic annotation with InterPro:IPR000283 reactive oxygen species metabolic process ; GO:0072593 | inferred from sequence or structural similarity with HGNC:7707 cellular respiration ; GO:0045333 | inferred from sequence or structural similarity with HGNC:7707 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P28331 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:7707 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000177280 "CG2286, ND75, NDUFS1, NUAM, ND-75" "IPR000283:NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR006656:Molybdopterin oxidoreductase, IPR010228:NADH:ubiquinone oxidoreductase, subunit G, IPR012675:Beta-grasp domain, IPR015405:NADH-quinone oxidoreductase, chain G, C-terminal, IPR019574:NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding, IPR006963:Molybdopterin oxidoreductase, 4Fe-4S domain, IPR029035:DHS-like NAD/FAD-binding domain" CG2286 11-Aug-17 DroID_v2017_08 Drer\ndufs1 - Cele\nuo-5 Xtro\ndufs1 Mmus\Ndufs1 Hsap\NDUFS1 increased cell number "lamellocyte | third instar larval stage,lamellocyte | larval stage" FBgn0022382 Pka-R2 "Protein kinase, cAMP-dependent, regulatory subunit type 2" http://flybase.org/reports/FBgn0022382 "FBgn0000353, FBgn0033472, FBgn0047292" protein_coding_gene cAMP-dependent protein kinase regulator activity ; GO:0008603 | inferred from electronic annotation with InterPro:IPR012198 protein binding ; GO:0005515 | inferred from physical interaction with Akap200 protein binding ; GO:0005515 | inferred from physical interaction with Pka-C1 regulation of protein phosphorylation ; GO:0001932 | inferred from electronic annotation with InterPro:IPR012198 locomotor rhythm ; GO:0045475 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | non-traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | non-traceable author statement behavioral response to cocaine ; GO:0048148 | non-traceable author statement rhythmic behavior ; GO:0007622 | traceable author statement behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype behavioral response to cocaine ; GO:0048148 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | non-traceable author statement behavioral response to ethanol ; GO:0048149 | traceable author statement cAMP-dependent protein kinase complex ; GO:0005952 | inferred from electronic annotation with InterPro:IPR012198 cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "pka-RII, Cos1, PKa-R2, PKA, PKA RII, PKA-RII, CG15862, Pka-RII, RII, RII[[DR]], pkA, Cos-1, Cos, Epa, cos1, BcDNA:GM01761, Pka-R2, PKA-R2" "IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR003117:cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, IPR012198:cAMP-dependent protein kinase regulatory subunit, IPR014710:RmlC-like jelly roll fold" CG15862 11-Aug-17 DroID_v2017_08 "Drer\prkar2ab, Drer\prkar1b, Drer\prkar1ab, Drer\prkar2aa, Drer\prkar2b, Drer\prkar1aa" Scer\BCY1 Cele\kin-2 "Xtro\prkar2a, Xtro\prkar2b, Xtro\prkar1a" "Mmus\Prkar2a, Mmus\Prkar1b, Mmus\Cnbd2, Mmus\Prkar2b, Mmus\Prkar1a" "Hsap\PRKAR2B, Hsap\CNBD2, Hsap\PRKAR1B, Hsap\PRKAR2A, Hsap\PRKAR1A" "viable,fertile,locomotor rhythm defective,chemical resistant,visible,neuroanatomy defective" "ovariole,follicle cell,nurse cell,ectopic,interfollicle cell,abdominal intersegmental nerve,presumptive embryonic/larval central nervous system,ventral nerve cord,abdominal segmental nerve,eye,costal cell,wing,haltere,trichogen cell" FBgn0017457 U2af38 U2 small nuclear riboprotein auxiliary factor 38 http://flybase.org/reports/FBgn0017457 FBgn0010626 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 pre-mRNA 3'-splice site binding ; GO:0030628 | inferred from biological aspect of ancestor with PANTHER:PTN000289700 poly-pyrimidine tract binding ; GO:0008187 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 RNA splicing ; GO:0008380 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype" U2AF ; GO:0089701 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "U2AF38, U2AF, dU2AF38, DU2AF38, CG3582, dU2AF[38], l(2)06751, U2af38, u2af38, U2AF 38, Utaf38" "IPR000504:RNA recognition motif domain, IPR000571:Zinc finger, CCCH-type, IPR009145:U2 auxiliary factor small subunit, IPR003954:RNA recognition motif domain, eukaryote" CG3582 11-Aug-17 DroID_v2017_08 "Drer\u2af1, Drer\zrsr2" - Cele\uaf-2 Xtro\u2af1 "Mmus\Zrsr1, Mmus\Zrsr2, Mmus\U2af1, Mmus\U2af1l4" "Hsap\ZRSR2, Hsap\U2AF1L4, Hsap\U2AF1, Hsap\U2AF1L5" " adult stage | female , adult stage | male " "lethal,recessive,partially,sterile,visible,partially lethal - majority die,wild-type,lethal - all die before end of larval stage,some die during larval stage" "crystal cell,sex comb,macrochaeta" DRSC00796 I -0.206589956 -1.867011555 -0.704197999 0.092476469 -0.021372329 0.940777771 FBgn0035709 eIF4E4 eukaryotic translation initiation factor 4E4 http://flybase.org/reports/FBgn0035709 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Thor translation initiation factor activity ; GO:0003743 | inferred from genetic interaction with SGD:S000005499 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity eukaryotic initiation factor 4G binding ; GO:0031370 | inferred from physical interaction with eIF4G1 RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay translational initiation ; GO:0006413 | inferred from genetic interaction with SGD:S000005499 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from physical interaction with eIF4G1 "CG10124, CT28485, eIF4E, BEST:GH01027, NEST:bs04e06, eIF4E4, eIF4E-4" "IPR001040:Translation Initiation factor eIF- 4e, IPR023398:Translation Initiation factor eIF- 4e-like, IPR019770:Eukaryotic translation initiation factor 4E (eIF-4E), conserved site" CG10124 11-Aug-17 DroID_v2017_08 "Drer\sesn2, Drer\eif4e1b, Drer\sesn1, Drer\si:zfos-80g12.1, Drer\eif4ea, Drer\eif4eb, Drer\eif4e1c" Scer\CDC33 "Cele\ife-5, Cele\ife-3, Cele\ife-2, Cele\ife-1" "Xtro\eif4e, Xtro\eif4e1b, Xtro\sesn1, Xtro\sesn3" "Mmus\Sesn1, Mmus\Eif4e1b, Mmus\Sesn2, Mmus\Eif4e, Mmus\Sesn3" "Hsap\SESN3, Hsap\EIF4E1B, Hsap\SESN1, Hsap\SESN2, Hsap\EIF4E" DRSC09701 IE -0.388960377 -1.711043038 -2.340334546 -0.993394952 -1.437978556 -0.426657049 FBgn0028582 lqf liquid facets http://flybase.org/reports/FBgn0028582 protein_coding_gene - autophagy ; GO:0006914 | inferred from direct assay synaptic vesicle endocytosis ; GO:0048488 | non-traceable author statement endocytosis ; GO:0006897 | non-traceable author statement positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement endocytosis ; GO:0006897 | inferred from mutant phenotype negative regulation of cardioblast cell fate specification ; GO:0009997 | inferred from mutant phenotype endocytosis ; GO:0006897 | traceable author statement regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype storage protein import into fat body ; GO:0015032 | inferred from direct assay - "Epsin, Lqf, epsin, LqF, CG8532, l(3)S011027, 0110/27, E(faf)bE25, anon-WO0118547.239, lqf, dEpsin" "IPR003903:Ubiquitin interacting motif, IPR008942:ENTH/VHS, IPR013809:ENTH domain" CG8532 11-Aug-17 DroID_v2017_08 "Drer\clint1a, Drer\epn2, Drer\clint1b, Drer\zgc:194578, Drer\epn1, Drer\epn3a, Drer\epn3b" "Scer\ENT4, Scer\ENT2, Scer\ENT5, Scer\ENT1, Scer\ENT3" "Cele\epn-1, Cele\rsd-3" "Xtro\epn3, Xtro\epn2" "Mmus\Enthd1, Mmus\Epn2, Mmus\Epn1, Mmus\Clint1, Mmus\Epn3" "Hsap\EPN1, Hsap\CLINT1, Hsap\ENTHD1, Hsap\EPN3, Hsap\EPN2" larval stage | third instar eye disc

"partially lethal - majority live,developmental rate defective,heat sensitive,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,viable" "nurse cell,heat sensitive,macrochaeta,cardioblast,supernumerary,embryonic/larval fat body,mitochondrial outer membrane,eye photoreceptor cell,somatic clone,mesothoracic tergum & chaeta | supernumerary,A1-7 dorsal acute muscle 1,embryonic somatic muscle,dorsal,retina,wing,wing vein,mesothoracic tergum & macrochaeta | supernumerary | somatic clone,eye photoreceptor cell & ommatidium | ectopic,eye,photoreceptor cell,ectopic,ommatidium,wing margin bristle,tarsal segment,mystery cell,leg sensillum,cell non-autonomous,photoreceptor cell R7,outer photoreceptor cell" DRSC27882 K 0.051745562 0.206104458 0.808185635 0.291004969 2.959109124 0.112070494 FBgn0037580 DppIII Dipeptidyl aminopeptidase III http://flybase.org/reports/FBgn0037580 protein_coding_gene dipeptidyl-peptidase activity ; GO:0008239 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay "CG7415, DPP, DppIII, DPP III" IPR005317:Dipeptidyl-peptidase 3 CG7415 11-Aug-17 DroID_v2017_08 Drer\dpp3 Scer\YOL057W Cele\dpt-1 Xtro\dpp3 Mmus\Dpp3 Hsap\DPP3 "viable,fertile" FBgn0025837 CG17636 - http://flybase.org/reports/FBgn0025837 - protein_coding_gene glutathione hydrolase activity ; GO:0036374 | inferred from electronic annotation with InterPro:IPR000101 glutathione catabolic process ; GO:0006751 | inferred from electronic annotation with InterPro:IPR000101 - "EG:23E12.1, CG17636" "IPR000101:Gamma-glutamyltranspeptidase, IPR029055:Nucleophile aminohydrolases, N-terminal" CG17636 11-Aug-17 DroID_v2017_08 "Drer\ggt1b, Drer\ggt1l2.2, Drer\si:ch73-236c18.3, Drer\ggt5a, Drer\ggt1a, Drer\ggt5b, Drer\si:dkey-222h21.12, Drer\LOC103909498, Drer\si:ch73-59p9.2" Scer\ECM38 "Cele\T19H12.6, Cele\T03D8.6, Cele\H14N18.4, Cele\Y7A9A.1, Cele\C53D5.5, Cele\Y97E10AR.2" "Xtro\ggt7, Xtro\ggt1, Xtro\ggt5" "Mmus\Ggt6, Mmus\Ggt1, Mmus\Ggt7, Mmus\Ggt5" "Hsap\GGTLC1, Hsap\GGT2, Hsap\GGT1, Hsap\GGT7, Hsap\GGT6, Hsap\GGTLC2, Hsap\GGT5" FBgn0036566 ClC-c Chloride channel-c http://flybase.org/reports/FBgn0036566 protein_coding_gene chloride channel activity ; GO:0005254 | inferred from sequence or structural similarity with ClC-a voltage-gated chloride channel activity ; GO:0005247 | inferred from biological aspect of ancestor with PANTHER:PTN001363397 chloride transmembrane transporter activity ; GO:0015108 | inferred from mutant phenotype endosomal lumen acidification ; GO:0048388 | inferred from mutant phenotype renal system process ; GO:0003014 | inferred from expression pattern chloride transmembrane transport ; GO:1902476 | inferred from sequence or structural similarity with ClC-a chloride transmembrane transport ; GO:1902476 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000189255 membrane ; GO:0016020 | inferred from sequence or structural similarity with ClC-a early endosome ; GO:0005769 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay "anon-WO0138359.7, CG5284, ClC-c, DmClCc, DmClC-c, Clc-c" "IPR000644:CBS domain, IPR001807:Chloride channel, voltage gated, IPR014743:Chloride channel, core" CG5284 11-Aug-17 DroID_v2017_08 "Drer\clcn5b, Drer\clcn3, Drer\clcn5a, Drer\clcn4" Scer\GEF1 "Cele\clh-1, Cele\clh-5" "Xtro\clcn4, Xtro\clcn5, Xtro\clcn3" "Mmus\Clcn5, Mmus\Clcn3, Mmus\Clcn4" "Hsap\CLCN3, Hsap\CLCN4, Hsap\CLCN5" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0000079 Amy-p Amylase proximal http://flybase.org/reports/FBgn0000079 "FBgn0014457, FBgn0035652, FBgn0042197" protein_coding_gene "cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR006046, InterPro:IPR006047, InterPro:IPR006048, InterPro:IPR006589 catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006046, InterPro:IPR006047, InterPro:IPR006048, InterPro:IPR006589, InterPro:IPR015902 alpha-amylase activity ; GO:0004556 | traceable author statement calcium ion binding ; GO:0005509 | traceable author statement" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006046, InterPro:IPR006047, InterPro:IPR006048, InterPro:IPR006589, InterPro:IPR013781 sleep ; GO:0030431 | inferred from expression pattern carbohydrate metabolic process ; GO:0005975 | traceable author statement" extracellular region ; GO:0005576 | inferred from direct assay "CG18730, Amy, AMY, amy, CG18640, Amy5, Amy4, Amy2, Amy1, alpha-Amy, AmyA, alpha-AMY, Amy-p, amy-p, Amy(p), Amy-proximal" "IPR006046:Alpha amylase, IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR006048:Alpha-amylase/branching enzyme, C-terminal all beta, IPR017853:Glycoside hydrolase superfamily, IPR031319:Alpha-amylase, C-terminal domain" CG18730 11-Aug-17 DroID_v2017_08 "Drer\amy2a, Drer\zgc:66313, Drer\zgc:92137" - Cele\C50B6.7 "Xtro\amy2a, Xtro\amy2b" "Mmus\Amy2b, Mmus\Amy2a1, Mmus\Amy1, Mmus\Amy2a4, Mmus\Amy2a3, Mmus\Amy2a2, Mmus\Amy2a5" "Hsap\AMY2A, Hsap\AMY1C, Hsap\AMY1B, Hsap\AMY1A, Hsap\AMY2B" adult stage adult midgut

adult stage " midgut

, midgut

{ - mapP00 } , adult midgut

" electrophoretic variant FBgn0052445 CG32445 - http://flybase.org/reports/FBgn0052445 protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718 aldose 1-epimerase activity ; GO:0004034 | inferred from biological aspect of ancestor with PANTHER:PTN000009552" galactose catabolic process via UDP-galactose ; GO:0033499 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 glucose metabolic process ; GO:0006006 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 - "CG12562, anon-WO0140519.131, CG32445" "IPR008183:Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013:Galactose mutarotase-like domain, IPR014718:Glycoside hydrolase-type carbohydrate-binding, IPR015443:Aldose 1-epimerase" CG32445 11-Aug-17 DroID_v2017_08 "Drer\rfng, Drer\mfng, Drer\galm, Drer\lfng" "Scer\YNR071C, Scer\YHR210C, Scer\GAL10" "Cele\C01B4.6, Cele\Y19D10A.16" "Xtro\rfng, Xtro\lfng, Xtro\galm" "Mmus\Rfng, Mmus\Galm, Mmus\Lfng, Mmus\Mfng" "Hsap\GALM, Hsap\LFNG, Hsap\MFNG, Hsap\RFNG" DRSC11678 E 0.508170854 0.894461997 1.83967461 -1.335382035 0.275878293 0.466984885 FBgn0038826 Syp Syncrip http://flybase.org/reports/FBgn0038826 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | inferred from direct assay "neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from mutant phenotype regulation of oskar mRNA translation ; GO:0046011 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype" ribonucleoprotein granule ; GO:0035770 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay postsynapse of neuromuscular junction ; GO:0098975 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "Syp, AI945337, cg17838, l(3)03806, anon-WO0118547.613, CG17838, syp, Syncrip" "IPR000504:RNA recognition motif domain, IPR006535:HnRNP R/Q splicing factor" CG17838 11-Aug-17 DroID_v2017_08 "Drer\rbm47, Drer\dnd1, Drer\hnrnpr, Drer\syncripl, Drer\a1cf, Drer\rbm46, Drer\syncrip" - "Cele\hrp-2, Cele\tdp-1" "Xtro\dnd1, Xtro\syncrip, Xtro\rbm47, Xtro\hnrnpr, Xtro\a1cf" "Mmus\Syncrip, Mmus\Dnd1, Mmus\Rbm46, Mmus\A1cf, Mmus\Hnrnpr, Mmus\Rbm47" "Hsap\SART3, Hsap\HNRNPR, Hsap\SYNCRIP, Hsap\A1CF, Hsap\DND1, Hsap\RBM46, Hsap\RBM47" "lethal,recessive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "dorsal appendage,germline clone,egg,pole cell,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0001994 crp cropped http://flybase.org/reports/FBgn0001994 "FBgn0024216, FBgn0026860, FBgn0041143, FBgn0065396" protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 nucleus ; GO:0005634 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from direct assay "AP4, AP-4, BG:DS02740.3, l(2)35Fd, dAP-4, l(2)k00809, 35F(AT)[[17]], l(2)k03505, l(2)00232, CG7664, l(2)SH1614, MS:35F.AT17, crp, l(2)SH2 1614, bHLHe63" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG7664 11-Aug-17 DroID_v2017_08 Drer\tfap4 - Cele\hlh-11 Xtro\tfap4 Mmus\Tfap4 Hsap\TFAP4 " larval stage | third instar ,, embryonic stage " "

, organism | ubiquitous

, salivary gland

" "viable,fertile,lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" "wing,eye,leg,trichogen cell,mesothoracic tergum" DRSC03515 IE -1.369710997 7.056391553 2.086493003 0.623990168 -1.355019968 -1.151520313 FBgn0031286 CG3862 - http://flybase.org/reports/FBgn0031286 protein_coding_gene - - - CG3862 "IPR000408:Regulator of chromosome condensation, RCC1, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG3862 11-Aug-17 DroID_v2017_08 "Drer\als2b, Drer\rcbtb2, Drer\rcbtb1, Drer\sergef, Drer\rccd1, Drer\rcc1, Drer\rpgra, Drer\herc1, Drer\rpgrb, Drer\herc2, Drer\als2a, Drer\ftr97, Drer\wbscr16" "Scer\SRM1, Scer\FMP25, Scer\ATS1" Cele\W09G3.7 "Xtro\wbscr16, Xtro\als2, Xtro\herc2, Xtro\rcbtb2, Xtro\herc1, Xtro\rcc1, Xtro\nek9, Xtro\rcbtb1, Xtro\als2cl" "Mmus\Rcbtb2, Mmus\Rpgr, Mmus\Wbscr16, Mmus\Nek9, Mmus\Rccd1, Mmus\Herc2, Mmus\Rcbtb1, Mmus\Herc1, Mmus\Als2, Mmus\Rcc1, Mmus\Sergef, Mmus\Gm15800" "Hsap\RCC1L, Hsap\RCBTB2, Hsap\RPGR, Hsap\RCC1, Hsap\RCCD1, Hsap\HECTD4, Hsap\HERC2, Hsap\SERGEF, Hsap\ALS2, Hsap\HERC1, Hsap\NEK9, Hsap\RCBTB1" "neuroanatomy defective,viable" anterior fascicle & synapse FBgn0037980 DCAF12 DDB1 and CUL4 associated factor 12 http://flybase.org/reports/FBgn0037980 protein_coding_gene - regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype - "CG3313, dcaf12, DCAF12" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG3313 11-Aug-17 DroID_v2017_08 Drer\dcaf12 - - Xtro\dcaf12 "Mmus\Dcaf12, Mmus\Dcaf12l2, Mmus\Dcaf12l1" "Hsap\DCAF12L2, Hsap\DCAF12, Hsap\DCAF12L1" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0025574 Pli Pellino http://flybase.org/reports/FBgn0025574 - protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000949730 kinase regulator activity ; GO:0019207 | inferred from mutant phenotype positive regulation of protein K48-linked ubiquitination ; GO:1902524 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement negative regulation of antimicrobial humoral response ; GO:0008348 | inferred from mutant phenotype negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | traceable author statement regulation of phosphorylation ; GO:0042325 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "PAP, CG5212, Pli, pli" "IPR006800:Pellino family, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5212 11-Aug-17 DroID_v2017_08 "Drer\peli1a, Drer\peli2, Drer\peli1b, Drer\peli3, Drer\LOC100334245" - Cele\peli-1 "Xtro\peli1, Xtro\peli2" "Mmus\Peli1, Mmus\Peli3, Mmus\Peli2" "Hsap\PELI2, Hsap\PELI1, Hsap\PELI3" " embryonic stage | 0-2hr , adult stage | female , embryonic stage -- adult stage " " embryonic stage , embryonic stage -- adult stage "

ubiquitous "immune response defective,recessive,lethal - all die before end of P-stage,some die during P-stage,viable" "embryonic head,germline clone,germ band" FBgn0015360 oxt peptide O-xylosyltransferase http://flybase.org/reports/FBgn0015360 "FBgn0035322, FBgn0052300" protein_coding_gene acetylglucosaminyltransferase activity ; GO:0008375 | inferred from electronic annotation with InterPro:IPR003406 protein xylosyltransferase activity ; GO:0030158 | non-traceable author statement protein xylosyltransferase activity ; GO:0030158 | inferred from direct assay chondroitin sulfate metabolic process ; GO:0030204 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from direct assay chondroitin sulfate proteoglycan biosynthetic process ; GO:0050650 | inferred from direct assay heparan sulfate proteoglycan metabolic process ; GO:0030201 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement D-xylose metabolic process ; GO:0042732 | inferred from direct assay chondroitin sulfate biosynthetic process ; GO:0030206 | non-traceable author statement membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003406 integral component of membrane ; GO:0016021 | non-traceable author statement "CG17771, CG17772, anon-i2, CG32300, oxt, Oxt, OXT, dOXT, dXylT" "IPR002889:Carbohydrate-binding WSC, IPR003406:Glycosyl transferase, family 14, IPR024448:Xylosyltransferase" CG32300 11-Aug-17 DroID_v2017_08 "Drer\wscd1a, Drer\xylt1, Drer\gcnt4a, Drer\gcnt7, Drer\wscd1b, Drer\gcnt3, Drer\gcnt4b, Drer\wscd2, Drer\si:dkeyp-87d8.8, Drer\xylt2" "Scer\WSC3, Scer\WSC2, Scer\WSC4, Scer\SLG1" "Cele\T09E11.6, Cele\T14B4.9, Cele\R07C3.3, Cele\ZK1225.2, Cele\Y51H4A.25, Cele\sqv-6, Cele\gly-15, Cele\gly-18, Cele\F26D2.3, Cele\T27F6.1, Cele\F30A10.4, Cele\gly-17, Cele\F35H8.2, Cele\T28F3.9, Cele\gly-1, Cele\gly-16, Cele\T09E11.9" "Xtro\xylt1, Xtro\gcnt1, Xtro\gcnt3, Xtro\gcnt2, Xtro\wscd2, Xtro\gcnt4, Xtro\xylt2" "Mmus\Gcnt7, Mmus\Xylt2, Mmus\Gcnt4, Mmus\Wscd2, Mmus\Wscd1, Mmus\Gcnt1, Mmus\Gcnt3, Mmus\Gcnt2, Mmus\Kremen2, Mmus\Xylt1" "Hsap\XYLT1, Hsap\GCNT3, Hsap\WSCD2, Hsap\GCNT1, Hsap\GCNT7, Hsap\GCNT2, Hsap\XYLT2, Hsap\GCNT4, Hsap\KREMEN2" "visible,viable" "eye,ommatidium" FBgn0053846 His1:CG33846 His1:CG33846 http://flybase.org/reports/FBgn0053846 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33846, His1:CG33846" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33846 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-261m9.12, Drer\si:dkey-108k21.14, Drer\si:ch73-36p18.1, Drer\zgc:110425, Drer\zgc:163061, Drer\h1f0, Drer\zgc:153405, Drer\h1m, Drer\h1fx, Drer\zgc:110216, Drer\si:dkey-108k21.21, Drer\si:dkey-108k21.10, Drer\si:ch1073-159d7.7, Drer\histh1l, Drer\si:ch211-113a14.24" Scer\HHO1 "Cele\hil-2, Cele\his-24, Cele\hil-3, Cele\hil-6, Cele\hil-1, Cele\hil-5, Cele\hil-4" - "Mmus\Hist1h1d, Mmus\Hist1h1c, Mmus\Hils1, Mmus\Hist1h1e, Mmus\Hist1h1b, Mmus\H1foo, Mmus\Hist1h1t, Mmus\H1fx, Mmus\Hist1h1a, Mmus\H1fnt" "Hsap\HIST1H1E, Hsap\HIST1H1A, Hsap\HIST1H1B, Hsap\H1F0, Hsap\H1FX, Hsap\HIST1H1T, Hsap\H1FOO, Hsap\HIST1H1D, Hsap\HIST1H1C, Hsap\H1FNT" FBgn0028983 Spn55B Serpin 55B http://flybase.org/reports/FBgn0028983 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from direct assay negative regulation of proteolysis ; GO:0045861 | inferred from direct assay extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG10913, sp6, sp-6, Sp6, Spn55B, Spn6" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG10913 11-Aug-17 DroID_v2017_08 "Drer\serpine2, Drer\agt, Drer\zgc:173729, Drer\serpini1, Drer\serpine1, Drer\serpinf2b, Drer\serpinc1, Drer\serpinf2a, Drer\serpinb1l1, Drer\zgc:113828, Drer\serpinb1l2, Drer\serpinf1, Drer\si:ch211-186e20.7, Drer\zgc:174259, Drer\serpinb1l3, Drer\si:ch1073-416d2.3, Drer\serpinb1, Drer\serpine3, Drer\zgc:174260, Drer\serpind1, Drer\serping1, Drer\serpina7, Drer\serpina1l" - "Cele\srp-7, Cele\srp-6, Cele\C28G1.2, Cele\srp-8, Cele\srp-1, Cele\srp-3, Cele\srp-2" "Xtro\serpinb5, Xtro\serpinb1, Xtro\serpinb11, Xtro\serpina3, Xtro\serpinb6, Xtro\serpina3m, Xtro\serpina3k, Xtro\serpini2, Xtro\serpind1, Xtro\serpina10, Xtro\serpine1, Xtro\serpina1, Xtro\serpini1, Xtro\serpinb4, Xtro\serpine2, Xtro\serpinc1" "Mmus\Serpinf2, Mmus\Serpind1, Mmus\Serpina3b, Mmus\Serpina1a, Mmus\Serpinb3b, Mmus\Gm11397, Mmus\Serpinb3d, Mmus\Serpinb1b, Mmus\Serpina6, Mmus\Serpina1c, Mmus\Serpinb9g, Mmus\Serpinf1, Mmus\Serpina10, Mmus\Serpina5, Mmus\Serpina3f, Mmus\Serpinb9e, Mmus\Serpina3i, Mmus\Serpina1f, Mmus\Serpinb9, Mmus\Serpinb12, Mmus\Serpini1, Mmus\Serpinb6b, Mmus\Serpinb9d, Mmus\Serpina3j, Mmus\Serpinb1c, Mmus\Serpinb13, Mmus\Serpinb8, Mmus\Serpina3k, Mmus\Serpina3a, Mmus\Serpina3g, Mmus\Serpina3n, Mmus\Serpina12, Mmus\Serpinb9c, Mmus\Serpinb6a, Mmus\Serpinb3a, Mmus\Serpinb1a, Mmus\Serpinb7, Mmus\Serpina16, Mmus\Serpinb9b, Mmus\Serpina3c, Mmus\Serpinb5, Mmus\Serpinb3c, Mmus\Serpina1d, Mmus\Serpinb2, Mmus\Serpinb6e, Mmus\Serpini2, Mmus\Serpinb6c, Mmus\Serpina1e, Mmus\Serpina9, Mmus\Serpine1, Mmus\Serpina11, Mmus\Serpine2, Mmus\Serpinc1, Mmus\Serpine3, Mmus\Serpinb9f, Mmus\Serpinb11, Mmus\Agt, Mmus\Serpinb6d, Mmus\Serpina7" "Hsap\SERPINF1, Hsap\SERPINA3, Hsap\SERPINB7, Hsap\SERPINF2, Hsap\SERPINA12, Hsap\SERPINA6, Hsap\SERPINA9, Hsap\SERPINB8, Hsap\SERPINB2, Hsap\SERPINB6, Hsap\SERPINB1, Hsap\SERPINB4, Hsap\SERPINE2, Hsap\SERPINI1, Hsap\SERPINA7, Hsap\AGT, Hsap\SERPINA4, Hsap\SERPINA11, Hsap\SERPINA2, Hsap\SERPINB12, Hsap\SERPINB13, Hsap\SERPINB11, Hsap\SERPINI2, Hsap\SERPINA1, Hsap\SERPINE1, Hsap\SERPINB10, Hsap\SERPINA10, Hsap\SERPINB9, Hsap\SERPINA5, Hsap\SERPINC1, Hsap\SERPINB5, Hsap\SERPINE3, Hsap\SERPINB3, Hsap\SERPIND1" "visible,lethal - all die before end of pupal stage,some die during pupal stage" mesothoracic tergum DRSC07694 I -1.622734267 -0.030584935 0.021696624 -0.224003217 -0.794897367 -1.150287355 FBgn0033699 RpS11 Ribosomal protein S11 http://flybase.org/reports/FBgn0033699 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000266, InterPro:IPR019979 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000266, InterPro:IPR019979 neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000266, InterPro:IPR019979 cytoplasm ; GO:0005737 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement nuclear chromosome ; GO:0000228 | inferred from direct assay" "CG8857, S11, clone 23, anon-EST:fe1D2, anon-MMS23, RpS11, M(2)48E, RPS11" "IPR000266:Ribosomal protein S17/S11, IPR012340:Nucleic acid-binding, OB-fold, IPR028333:Ribosomal protein S17, archaeal/eukaryotic, IPR019979:Ribosomal protein S17, conserved site, IPR032440:40S ribosomal protein S11, N-terminal" CG8857 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-159f12.2, Drer\rps11" "Scer\RPS11B, Scer\RPS11A" Cele\rps-11 Xtro\rps11 Mmus\Rps11 Hsap\RPS11 "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC22700 IEK 3.994574621 -0.054075813 3.091891144 -0.803494123 1.958534934 3.45436981 FBgn0037728 CG16817 - http://flybase.org/reports/FBgn0037728 protein_coding_gene molecular_function ; GO:0003674 | no biological data available Golgi organization ; GO:0007030 | inferred from mutant phenotype nuclear membrane ; GO:0031965 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "YC17, CG16817, cg16817" "IPR007052:CS domain, IPR008978:HSP20-like chaperone" CG16817 11-Aug-17 DroID_v2017_08 "Drer\ptges3a, Drer\si:ch211-131k2.3, Drer\hacd3, Drer\ptges3b" Scer\SBA1 "Cele\ZC395.10, Cele\R10E4.9" "Xtro\ptges3, Xtro\hacd3" "Mmus\Aarsd1, Mmus\Ptges3l, Mmus\Ptges3, Mmus\Hacd3" "Hsap\AARSD1, Hsap\PTGES3L, Hsap\PTGES3, Hsap\HACD3" "viable,fertile" DRSC27806 K -0.291768891 0.077041335 1.003451211 1.24955133 1.102098879 1.885138397 FBgn0028471 Nab2 Nuclear polyadenosine RNA-binding 2 http://flybase.org/reports/FBgn0028471 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 poly(A) binding ; GO:0008143 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of mRNA polyadenylation ; GO:1900364 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "RE28534, BEST:GH27517, BcDNA:LD27873, clone 1.43, anon-EST:Liang-1.43, CG5720, dNab2, Nab2, DnAB2" "IPR000571:Zinc finger, CCCH-type" CG5720 11-Aug-17 DroID_v2017_08 Drer\zc3h14 Scer\NAB2 Cele\sut-2 - Mmus\Zc3h14 Hsap\ZC3H14 "some die during pharate adult stage,majority die during pharate adult stage,locomotor behavior defective,short lived,flight defective,lethal - all die before end of P-stage,viable,visible" "embryonic/larval hemocyte | third instar larval stage,wing,macrochaeta,microchaeta,scutellar bristle,eye" FBgn0250823 gish gilgamesh http://flybase.org/reports/FBgn0250823 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966" endocytosis ; GO:0006897 | inferred from biological aspect of ancestor with PANTHER:PTN000226268 ommatidial rotation ; GO:0016318 | inferred from mutant phenotype inferred from genetic interaction with nmo peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype inferred from genetic interaction with para protein phosphorylation ; GO:0006468 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from direct assay negative regulation of actin nucleation ; GO:0051126 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from biological aspect of ancestor with PANTHER:PTN000226268 regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein phosphorylation ; GO:0006468 | inferred from direct assay regulation of endocytic recycling ; GO:2001135 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay sperm individualization complex ; GO:0070864 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 "gish, CG6963, CKIgamma, Hrr25, ms(3)89B, CKI-related, anon-WO0118547.425, CK1, Gish, NEST:bs27c08, spider, CK1[[gamma]], CK1gamma, Spider, CK1-gamma" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR022247:Casein kinase 1 gamma C-terminal" CG6963 11-Aug-17 DroID_v2017_08 "Drer\csnk1g2a, Drer\csnk1g1, Drer\csnk1g2b" "Scer\YCK1, Scer\YCK3, Scer\HRR25, Scer\YCK2" "Cele\B0218.5, Cele\csnk-1, Cele\tag-191" "Xtro\csnk1g2, Xtro\csnk1g1, Xtro\csnk1g3" "Mmus\Csnk1g1, Mmus\Csnk1g3, Mmus\Csnk1g2" "Hsap\CSNK1G3, Hsap\CSNK1G2, Hsap\CSNK1G1" DRSC16154 K -0.732371574 -1.476310984 0.773374832 1.3502412 0.283957945 7.73610614 FBgn0024956 Mat1 Menage a trois 1 http://flybase.org/reports/FBgn0024956 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 cyclin-dependent protein serine/threonine kinase activator activity ; GO:0061575 | inferred from electronic annotation with InterPro:IPR004575 transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | contributes_to inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | contributes_to inferred from direct assay" positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from electronic annotation with InterPro:IPR004575 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000293747 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:7181 inferred from sequence or structural similarity with SGD:S000002868 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000293747 regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | inferred from direct assay "holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:1594 inferred from sequence or structural similarity with HGNC:7181 inferred from sequence or structural similarity with SGD:S000002868 carboxy-terminal domain protein kinase complex ; GO:0032806 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from physical interaction with hay, CycH, mrn, Xpd, Cdk7 holo TFIIH complex ; GO:0005675 | inferred from direct assay" "MAT1, CG7614, Mat1, AT-1" "IPR001841:Zinc finger, RING-type, IPR004575:Cdk-activating kinase assembly factor MAT1/Tfb3, IPR015877:Cdk-activating kinase assembly factor MAT1, centre, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7614 11-Aug-17 DroID_v2017_08 Drer\mnat1 Scer\TFB3 Cele\mnat-1 Xtro\mnat1 Mmus\Mnat1 Hsap\MNAT1 "viable,visible" "trichogen cell,tormogen cell,mesothoracic tergum" FBgn0028717 Lnk Lnk http://flybase.org/reports/FBgn0028717 protein_coding_gene signaling adaptor activity ; GO:0035591 | inferred from electronic annotation with InterPro:IPR030523 signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR015012 signal transducer activity ; GO:0004871 | non-traceable author statement female mating behavior ; GO:0060180 | inferred from mutant phenotype regulation of growth ; GO:0040008 | inferred from mutant phenotype positive regulation of insulin-like growth factor receptor signaling pathway ; GO:0043568 | inferred from mutant phenotype TORC1 signaling ; GO:0038202 | inferred from mutant phenotype positive regulation of insulin receptor signaling pathway ; GO:0046628 | inferred from mutant phenotype signal transduction ; GO:0007165 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay "CG5908, lnk, CG17367, Lnk, dSH2B, CG 17367, LNK" "IPR000980:SH2 domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR015012:Phenylalanine zipper, IPR030523:SH2B adapter protein" CG17367 11-Aug-17 DroID_v2017_08 "Drer\shc3, Drer\sh2b3, Drer\sh2b2, Drer\sh2b1" - - "Xtro\sh2b3, Xtro\sh2b2" "Mmus\Fes, Mmus\Sh2b3, Mmus\Sh2b2, Mmus\Sh2b1" "Hsap\SH2B3, Hsap\SH2B1, Hsap\SH2B2, Hsap\FES" "short lived,starvation stress response defective,oxidative stress response defective,viable,fertile,small body,decreased cell size,decreased cell number,female sterile,male fertile,long lived,recessive,female semi-sterile,mating defective,visible,somatic clone" "wing blade,wing,egg chamber,head,somatic clone,ommatidium,eye,ovary,oocyte,rhabdomere,wing disc,eye photoreceptor cell" DRSC16729 I -0.53503895 -1.832624049 -0.537402868 -0.947140998 -0.170842185 0.352440767 FBgn0053861 His1:CG33861 His1:CG33861 http://flybase.org/reports/FBgn0053861 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33861, His1:CG33861" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33861 11-Aug-17 DroID_v2017_08 "Drer\zgc:163061, Drer\zgc:110216, Drer\si:ch73-368j24.11, Drer\LOC569982, Drer\si:dkey-108k21.10, Drer\si:ch211-113a14.18, Drer\si:ch1073-153i20.4, Drer\h1f0, Drer\si:dkey-108k21.14, Drer\si:dkey-108k21.21, Drer\histh1l, Drer\si:ch1073-159d7.7, Drer\h1fx, Drer\si:dkey-261m9.12, Drer\h1m, Drer\zgc:153405, Drer\si:ch73-368j24.12, Drer\zgc:110425, Drer\si:dkey-23a13.17, Drer\si:ch211-113a14.24, Drer\si:ch73-36p18.1, Drer\si:dkey-23a13.9" Scer\HHO1 "Cele\his-24, Cele\hil-1, Cele\hil-6, Cele\hil-3, Cele\hil-5, Cele\hil-4, Cele\hil-2" Xtro\h1f0 "Mmus\H1foo, Mmus\Hist1h1b, Mmus\Hist1h1d, Mmus\H1fnt, Mmus\H1fx, Mmus\Hist1h1t, Mmus\Hist1h1e, Mmus\H1f0, Mmus\Hils1, Mmus\Hist1h1a, Mmus\Hist1h1c" "Hsap\HIST1H1A, Hsap\H1F0, Hsap\H1FOO, Hsap\HIST1H1D, Hsap\H1FNT, Hsap\HIST1H1E, Hsap\H1FX, Hsap\HIST1H1T, Hsap\HIST1H1B, Hsap\HIST1H1C" FBgn0033958 jef jet fuel http://flybase.org/reports/FBgn0033958 protein_coding_gene - detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype - "CG12858, jef" "IPR024989:Major facilitator superfamily associated domain, IPR020846:Major facilitator superfamily domain" CG12858 11-Aug-17 DroID_v2017_08 "Drer\mfsd6l, Drer\mfsd6b, Drer\mfsd6a" - "Cele\mct-3, Cele\mct-2, Cele\R13A5.9, Cele\mct-4, Cele\mct-6, Cele\mct-5, Cele\mct-1" "Xtro\mfsd6, Xtro\mfsd6l" "Mmus\Mfsd6l, Mmus\Mfsd6" "Hsap\MFSD6, Hsap\MFSD6L" viable FBgn0038466 CG8907 - http://flybase.org/reports/FBgn0038466 protein_coding_gene molecular_function ; GO:0003674 | no biological data available olfactory behavior ; GO:0042048 | inferred from sequence or structural similarity with aru synapse ; GO:0045202 | inferred from sequence or structural similarity with aru "LP01469p, CG8907" "IPR001452:SH3 domain, IPR013625:Tensin/EPS8 phosphotyrosine-binding domain, IPR011993:PH domain-like, IPR033928:Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain" CG8907 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-70c5.1, Drer\si:dkey-287h13.1, Drer\eps8l3b, Drer\eps8l3a, Drer\eps8, Drer\si:ch1073-89b12.1, Drer\eps8l1" - Cele\eps-8 "Xtro\eps8l3, Xtro\arhgef7, Xtro\eps8" "Mmus\Eps8, Mmus\Eps8l1, Mmus\Nck1, Mmus\Eps8l2, Mmus\Eps8l3" "Hsap\EPS8L3, Hsap\EPS8L2, Hsap\EPS8, Hsap\EPS8L1, Hsap\NCK1" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033065 Cyp6w1 Cyp6w1 http://flybase.org/reports/FBgn0033065 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 sensory perception of smell ; GO:0007608 | inferred from expression pattern" - "6w1, CG8345, AntP450, Cyp6w1, CYP6W1, Cyp6W1, CYP6w1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG8345 11-Aug-17 DroID_v2017_08 "Drer\cyp3c1, Drer\cyp3c4, Drer\cyp3a65, Drer\tbxas1, Drer\cyp26a1, Drer\cyp3c2, Drer\cyp3c3" "Scer\ERG11, Scer\ERG5" "Cele\cyp-13A8, Cele\cyp-13A6, Cele\cyp-13A10, Cele\cyp-13A2, Cele\cyp-25A6, Cele\cyp-13A3, Cele\cyp-25A4, Cele\cyp-25A1, Cele\cyp-13A4, Cele\cyp-44A1, Cele\cyp-13A12, Cele\cyp-25A3, Cele\cyp-13A7, Cele\cyp-13A1, Cele\cyp-13A5, Cele\cyp-13A11, Cele\cyp-43A1, Cele\cyp-13B2, Cele\cyp-25A2, Cele\cyp-13B1" "Xtro\cyp3a4, Xtro\LOC100494419, Xtro\tbxas1, Xtro\cyp3a5" "Mmus\Cyp3a57, Mmus\Cyp4f37, Mmus\Cyp3a11, Mmus\Cyp3a44, Mmus\Tbxas1, Mmus\Cyp26a1, Mmus\Cyp3a13, Mmus\Cyp3a59, Mmus\Cyp3a41b, Mmus\Cyp3a41a, Mmus\Cyp3a16, Mmus\Cyp3a25" "Hsap\TBXAS1, Hsap\CYP3A7, Hsap\CYP3A4, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A43, Hsap\CYP3A5, Hsap\CYP26A1" adult stage " leg

, adult head

, antennal segment 3

" FBgn0039713 RpS8 Ribosomal protein S8 http://flybase.org/reports/FBgn0039713 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001047, InterPro:IPR018283 neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000044490 translation ; GO:0006412 | inferred from sequence or structural similarity larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype" ribosome ; GO:0005840 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CG7808, anon-EST:Liang-1.56, S8, clone 1.56, BcDNA:SD17528, anon-EST:fe1A2, BcDNA:RH06886, RpS8, Rps8, Rp S8, chr3R:25688477..25688608, RPS8" "IPR018283:Ribosomal protein S8e, conserved site, IPR001047:Ribosomal protein S8e, IPR022309:Ribosomal protein S8e/ribosomal biogenesis NSA2" CG7808 11-Aug-17 DroID_v2017_08 "Drer\rps8b, Drer\rps8a" "Scer\RPS8B, Scer\RPS8A" Cele\rps-8 Xtro\rps8 Mmus\Rps8 Hsap\RPS8 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC16318 EK -0.598986188 0.616229562 2.527015525 -3.563896316 1.545768528 2.779666009 FBgn0036728 UQCR-Q Ubiquinol-cytochrome c reductase ubiquinone-binding protein http://flybase.org/reports/FBgn0036728 protein_coding_gene ubiquinol-cytochrome-c reductase activity ; GO:0008121 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000950370 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:O14949 ubiquinone binding ; GO:0048039 | inferred from sequence or structural similarity with UniProtKB:O14949 "mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:O14949 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000950370" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:O14949 lipid particle ; GO:0005811 | inferred from direct assay mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN000950370 "BcDNA:AT13736, CG7580, UCRQ, UQCR-Q" IPR004205:Cytochrome b-c1 complex subunit 8 CG7580 11-Aug-17 DroID_v2017_08 Drer\uqcrq Scer\QCR8 "Cele\R07E4.3, Cele\F45H10.2" Xtro\uqcrq Mmus\Uqcrq Hsap\UQCRQ "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0052679 CG32679 - http://flybase.org/reports/FBgn0052679 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model CG32679 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG32679 11-Aug-17 DroID_v2017_08 "Drer\LOC101883528, Drer\r3hdml, Drer\glipr1b, Drer\crispld1b, Drer\pi15b, Drer\LOC100536500, Drer\crispld1a, Drer\pi15a, Drer\glipr2, Drer\glipr2l, Drer\crispld2" "Scer\PRY2, Scer\PRY3, Scer\PRY1" "Cele\scl-5, Cele\scl-21, Cele\scl-3, Cele\scl-23, Cele\scl-13, Cele\scl-2, Cele\scl-7, Cele\scl-8, Cele\C07A4.3, Cele\scl-17, Cele\scl-12, Cele\scl-1, Cele\scl-14, Cele\F09B9.5, Cele\scl-15, Cele\scl-20, Cele\scl-11, Cele\scl-9, Cele\scl-19, Cele\scl-10, Cele\scl-18, Cele\scl-6" "Xtro\crispld2, Xtro\crisp1, Xtro\MGC108118, Xtro\crisp3, Xtro\glipr2, Xtro\r3hdml, Xtro\crisp2, Xtro\pi15" "Mmus\R3hdml, Mmus\Glipr1l2, Mmus\Crispld2, Mmus\Crisp3, Mmus\Pi15, Mmus\Crisp4, Mmus\Crisp2, Mmus\Crispld1, Mmus\Clec18a, Mmus\Pi16, Mmus\Glipr2, Mmus\Crisp1, Mmus\Glipr1, Mmus\Glipr1l1" "Hsap\PI15, Hsap\CRISP2, Hsap\R3HDML, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\CLEC18B, Hsap\CRISPLD2, Hsap\PI16, Hsap\GLIPR2, Hsap\CRISP1, Hsap\CRISPLD1, Hsap\CLEC18A, Hsap\GLIPR1" "viable,fertile" DRSC17644 I 2.606495757 0.949251896 1.126414319 0.128913923 0.954218873 -0.201171419 FBgn0015776 nrv1 nervana 1 http://flybase.org/reports/FBgn0015776 FBgn0014867 protein_coding_gene cation transmembrane transporter activity ; GO:0008324 | contributes_to inferred from direct assay sodium:potassium-exchanging ATPase activity ; GO:0005391 | contributes_to inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A6MHQ4 potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR000402 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR000402 cation transport ; GO:0006812 | inferred from direct assay sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred from electronic annotation with InterPro:IPR000402 plasma membrane ; GO:0005886 | inferred from direct assay sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred by curator from GO:0005391 "Nrv, Na[+]/K[+] ATPase, Nrv1, NaK ATPase, Na,K-ATPase, Na[+]/K[+]ATPase, Na[+]/K[+]-ATPase, 42kDa, CG9258, nrv1, NKA-alpha, nervana" IPR000402:Sodium/potassium-transporting ATPase subunit beta CG9258 11-Aug-17 DroID_v2017_08 "Drer\atp1b3b, Drer\atp1b4, Drer\atp1b1b, Drer\atp1b1a, Drer\atp1b3a, Drer\atp1b2b, Drer\atp1b2a" - "Cele\nkb-1, Cele\nkb-2, Cele\nkb-3" "Xtro\atp4b, Xtro\atp1b3, Xtro\atp1b4, Xtro\atp1b1, Xtro\atp1b2" "Mmus\Atp1b4, Mmus\Atp4b, Mmus\Atp1b3, Mmus\Atp1b1, Mmus\Atp1b2" "Hsap\ATP1B4, Hsap\ATP1B1, Hsap\ATP1B3, Hsap\ATP4B, Hsap\ATP1B2" adult stage " adult thorax

, adult head

, adult abdomen

" " embryonic stage , adult stage , embryonic stage -- adult stage " " central nervous system

, adult abdomen

, embryonic peripheral nervous system

, pupal/adult digestive system

, embryonic/larval garland cell

, leg

, commissure

, adult head

, longitudinal connective

, adult muscle system

, adult thorax

, Malpighian tubule

, head

, embryonic/larval posterior spiracle

" viable DRSC03382 I 0.07862726 2.940846423 -0.270876617 0.293291333 -0.474226552 -0.286744536 FBgn0036299 Tsf2 Transferrin 2 http://flybase.org/reports/FBgn0036299 protein_coding_gene iron ion binding ; GO:0005506 | inferred from direct assay septate junction assembly ; GO:0019991 | inferred from mutant phenotype "extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR018195 recycling endosome ; GO:0055037 | inferred from physical interaction with Rab11 cytosol ; GO:0005829 | inferred from direct assay anchored component of plasma membrane ; GO:0046658 | inferred from direct assay early endosome ; GO:0005769 | inferred from physical interaction with Rab5 plasma membrane ; GO:0005886 | inferred from direct assay septate junction ; GO:0005918 | inferred from physical interaction with Nrx-IV, Cont, Nrg" "MTf, CG10620, Tsf2, tsf2" "IPR018195:Transferrin family, iron binding site, IPR001156:Transferrin-like domain" CG10620 11-Aug-17 DroID_v2017_08 "Drer\mfi2, Drer\otomp, Drer\srprb, Drer\zgc:172271, Drer\tfa" - Cele\F54D5.4 "Xtro\mfi2, Xtro\depdc5, Xtro\tf" "Mmus\1300017J02Rik, Mmus\Srprb, Mmus\Trf, Mmus\Ltf, Mmus\Mfi2" "Hsap\TF, Hsap\LTF, Hsap\SRPRB, Hsap\MELTF" "lethal,lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval dorsal trunk,septate junction | embryonic stage 16" FBgn0000416 Sap-r Saposin-related http://flybase.org/reports/FBgn0000416 "FBgn0026286, FBgn0027566" protein_coding_gene enzyme activator activity ; GO:0008047 | inferred from biological aspect of ancestor with PANTHER:PTN001352635 G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN001352635 sphingolipid metabolic process ; GO:0006665 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype lysosome ; GO:0005764 | inferred from electronic annotation with InterPro:IPR008373 fusome ; GO:0045169 | inferred from direct assay "sap-r, P110, Sapr, DAPA, anon-EST:ParkEST270, CG12070, BcDNA:GH08312, Apa, Sap-r, Ov9, Sap-R" "IPR003119:Saposin A-type domain, IPR007856:Saposin-like type B, region 1, IPR008138:Saposin B type, region 2, IPR008139:Saposin B type domain, IPR008373:Saposin, IPR011001:Saposin-like" CG12070 11-Aug-17 DroID_v2017_08 "Drer\psap, Drer\sftpbb, Drer\sftpba" - "Cele\spp-13, Cele\K02A11.4, Cele\spp-15, Cele\spp-8, Cele\spp-10" Xtro\psap "Mmus\Sftpb, Mmus\Psapl1, Mmus\Psap" "Hsap\SFTPB, Hsap\PSAPL1, Hsap\PSAP" "viable,fertile" FBgn0050344 CG30344 - http://flybase.org/reports/FBgn0050344 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR005829 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701 response to toxic substance ; GO:0009636 | inferred from expression pattern renal tubular secretion ; GO:0097254 | inferred from expression pattern" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701" "CG8054, CG30344, MET" "IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG30344 11-Aug-17 DroID_v2017_08 "Drer\slc46a3, Drer\si:ch211-262i1.4, Drer\slc46a1, Drer\zgc:174356, Drer\LOC100002406, Drer\si:dkey-5g14.1" Scer\YJL163C "Cele\F40F9.5, Cele\Y4C6B.5, Cele\Y43F8A.5" "Xtro\slc46a2, Xtro\slc46a1" "Mmus\Slc46a2, Mmus\Slc46a3, Mmus\Slc46a1" "Hsap\SLC46A1, Hsap\SLC46A2, Hsap\SLC46A3" viable FBgn0030468 CG1622 - http://flybase.org/reports/FBgn0030468 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay CG1622 IPR005037:Pre-mRNA-splicing factor 38 CG1622 11-Aug-17 DroID_v2017_08 Drer\prpf38b - Cele\Y108G3AL.2 Xtro\prpf38b Mmus\Prpf38b Hsap\PRPF38B viable FBgn0086674 Tango13 Transport and Golgi organization 13 http://flybase.org/reports/FBgn0086674 protein_coding_gene protein-tyrosine sulfotransferase activity ; GO:0008476 | inferred from biological aspect of ancestor with PANTHER:PTN000300376 protein secretion ; GO:0009306 | inferred from mutant phenotype peptidyl-tyrosine sulfation ; GO:0006478 | inferred from biological aspect of ancestor with PANTHER:PTN000300376 Golgi apparatus ; GO:0005794 | inferred from direct assay "CG32629, CG15758, CG32632, TANGO13, CG1573, CG15759, Tango13, CG32629/CG32632" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026634:Protein-tyrosine sulfotransferase" CG32632 11-Aug-17 DroID_v2017_08 "Drer\tpst1l, Drer\tpst2, Drer\tpst1" - "Cele\tpst-1, Cele\tpst-2" "Xtro\tpst1, Xtro\tpst2" "Mmus\Tpst2, Mmus\Tpst1" "Hsap\TPST1, Hsap\TPST2" "lethal,viable,partially lethal - majority die,visible,body color defective,some die during pupal stage" "trichogen cell,mesothoracic tergum" """DRSC19723, DRSC25422"" " IK FBgn0041087 wun2 wunen-2 http://flybase.org/reports/FBgn0041087 protein_coding_gene phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000017950 lipid transporter activity ; GO:0005319 | inferred from direct assay phosphatidate phosphatase activity ; GO:0008195 | non-traceable author statement lipid phosphatase activity ; GO:0042577 | inferred from direct assay phosphatidate phosphatase activity ; GO:0008195 | inferred from sequence or structural similarity with wun germ cell repulsion ; GO:0035233 | traceable author statement pole cell migration ; GO:0007280 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype inferred from genetic interaction with wun signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 phospholipid dephosphorylation ; GO:0046839 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 pole cell development ; GO:0007277 | inferred from mutant phenotype dephosphorylation ; GO:0016311 | non-traceable author statement germ cell development ; GO:0007281 | inferred from mutant phenotype phospholipid metabolic process ; GO:0006644 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 ectopic germ cell programmed cell death ; GO:0035234 | traceable author statement germ cell repulsion ; GO:0035233 | inferred from genetic interaction with wun germ cell migration ; GO:0008354 | traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 plasma membrane ; GO:0005886 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "N14, wun-2, CG8805, Tunen, WUN-like, Pap2G, DrPAP2[G], CK02248, BEST:CK02248, wun2, LPP-like, Wun2" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG8805 11-Aug-17 DroID_v2017_08 "Drer\plppr2a, Drer\LOC794598, Drer\plppr3a, Drer\plpp1a, Drer\ppap2d, Drer\plppr1, Drer\plppr5b, Drer\plppr4a, Drer\plppr2b, Drer\plppr3b, Drer\plpp2b, Drer\plpp2a, Drer\plppr5a, Drer\plpp3" "Scer\DPP1, Scer\LPP1" "Cele\F13E6.5, Cele\T28D9.3, Cele\F53C3.13, Cele\T06D8.3" "Xtro\LOC100135382, Xtro\plpp5, Xtro\plpp3, Xtro\plpp1, Xtro\plpp2" "Mmus\Plppr5, Mmus\Plppr3, Mmus\Plppr4, Mmus\Plpp1, Mmus\Plpp5, Mmus\Plpp2, Mmus\Plpp3, Mmus\Plpp4, Mmus\Plppr2, Mmus\Plppr1" "Hsap\PLPP2, Hsap\PLPPR4, Hsap\PLPP3, Hsap\PLPPR2, Hsap\PLPPR5, Hsap\PLPPR3, Hsap\PLPP1, Hsap\PLPP5, Hsap\PLPPR1, Hsap\PLPP4" "viable,neuroanatomy defective,sterile,decreased cell number,maternal effect,increased cell death,germline clone,visible,partially lethal - majority die,some die during pupal stage" "anterior fascicle & synapse,germline cell,pole cell | embryonic stage,pole cell & gonad & embryo | non-rescuable maternal effectw45-19g),pole cell,non-rescuable maternal effect,ovary & germ cell & adult | non-rescuable maternal effectw45-19g),maternal effect,germline clone,germline cell | embryonic stage 15,germline cell | embryonic stage 16,mesothoracic tergum" FBgn0035839 CG7550 - http://flybase.org/reports/FBgn0035839 protein_coding_gene "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR012864" oxidation-reduction process ; GO:0055114 | inferred from biological aspect of ancestor with PANTHER:PTN000539916 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000539917 CG7550 "IPR012864:Cysteine oxygenase/2-aminoethanethiol dioxygenase, IPR011051:RmlC-like cupin domain, IPR014710:RmlC-like jelly roll fold" CG7550 11-Aug-17 DroID_v2017_08 "Drer\adob, Drer\LOC103909024, Drer\adoa" - Cele\Y50D4C.6 Xtro\ado Mmus\Ado Hsap\ADO "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0000299 Col4a1 Collagen type IV alpha 1 http://flybase.org/reports/FBgn0000299 - protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from electronic annotation with InterPro:IPR001442 dorsal closure ; GO:0007391 | traceable author statement oviduct morphogenesis ; GO:0035848 | inferred from mutant phenotype intestinal epithelial structure maintenance ; GO:0060729 | inferred from mutant phenotype cardiac muscle cell development ; GO:0055013 | inferred from mutant phenotype post-embryonic digestive tract morphogenesis ; GO:0048621 | inferred from mutant phenotype collagen trimer ; GO:0005581 | inferred from electronic annotation with InterPro:IPR001442 collagen type IV trimer ; GO:0005587 | non-traceable author statement collagen type IV trimer ; GO:0005587 | traceable author statement "Dcg1, DCg1, Cgc25, CG25C, CT12803, alpha(IV)1/Cg25C, Dcg, alpha1, gp125, CG4145, Cgc25C, Cg25C, Coll IV, Coll, cg25c, cg25C, col4a1, Col IV alpha(1), dcg1, Col4a1" "IPR001442:Collagen IV, non-collagenous, IPR008160:Collagen triple helix repeat, IPR016187:C-type lectin fold" CG4145 11-Aug-17 DroID_v2017_08 "Drer\col5a2b, Drer\col4a2, Drer\si:ch211-106n13.3, Drer\LOC101883924, Drer\zmp:0000000760, Drer\col1a1a, Drer\si:dkey-61l1.4, Drer\col27a1a, Drer\col11a1a, Drer\col15a1b, Drer\col14a1a, Drer\col11a1b, Drer\col4a1, Drer\col9a1a, Drer\col5a1, Drer\col6a4a, Drer\col4a3, Drer\col5a2a, Drer\col9a2, Drer\col1a2, Drer\col17a1b, Drer\si:ch211-196i2.1, Drer\col17a1a, Drer\col12a1b, Drer\col4a4, Drer\col1a1b, Drer\col6a2, Drer\col4a6, Drer\LOC100538221, Drer\col27a1b, Drer\col11a2, Drer\col16a1, Drer\LOC101884357, Drer\col9a1b, Drer\col4a5, Drer\col28a1a, Drer\col6a1, Drer\col2a1b, Drer\col6a3, Drer\col2a1a, Drer\si:dkey-225n22.4, Drer\wu:fc38h03, Drer\col28a1a, Drer\col7a1l, Drer\zgc:153049" - "Cele\col-143, Cele\col-7, Cele\col-63, Cele\col-182, Cele\col-98, Cele\col-129, Cele\dpy-5, Cele\col-140, Cele\col-142, Cele\col-62, Cele\let-2, Cele\col-91, Cele\col-80, Cele\col-45, Cele\emb-9, Cele\col-65, Cele\col-161, Cele\col-111, Cele\col-156, Cele\col-147, Cele\col-39, Cele\col-19, Cele\rol-8, Cele\col-8, Cele\col-162, Cele\col-76, Cele\col-146, Cele\col-88, Cele\col-107, Cele\dpy-9, Cele\col-178, Cele\cle-1, Cele\col-179, Cele\col-120, Cele\col-53, Cele\col-141" "Xtro\col7a1, Xtro\col4a2, Xtro\col24a1, Xtro\col2a1, Xtro\col4a5, Xtro\col1a1, Xtro\col4a1, Xtro\col6a2, Xtro\col27a1, Xtro\col1a2, Xtro\col14a1, Xtro\col11a2, Xtro\col4a6, Xtro\col3a1, Xtro\col5a1, Xtro\LOC100486063" "Mmus\Col24a1, Mmus\Col25a1, Mmus\Col15a1, Mmus\Col4a5, Mmus\Col3a1, Mmus\Col13a1, Mmus\Col9a3, Mmus\Col4a3, Mmus\Col22a1, Mmus\Col27a1, Mmus\Col28a1, Mmus\Col6a1, Mmus\Tnn, Mmus\Col19a1, Mmus\Vwa1, Mmus\8030474K03Rik, Mmus\Vwa2, Mmus\Col17a1, Mmus\Col4a1, Mmus\Col23a1, Mmus\Col5a3, Mmus\Col5a2, Mmus\4933412E24Rik, Mmus\Col4a2, Mmus\Col7a1, Mmus\Col5a1, Mmus\Col4a6, Mmus\Col20a1, Mmus\Col11a2, Mmus\Col6a3, Mmus\Col6a6, Mmus\Col9a1, Mmus\Col16a1, Mmus\Col1a1, Mmus\Col11a1, Mmus\Col26a1, Mmus\Col6a4, Mmus\Col4a4, Mmus\Col2a1, Mmus\Col6a5, Mmus\Col1a2, Mmus\Col14a1" "Hsap\COL5A3, Hsap\COL4A6, Hsap\COL6A3, Hsap\VWA2, Hsap\COL14A1, Hsap\COL16A1, Hsap\COL1A2, Hsap\COL4A2, Hsap\COL5A1, Hsap\COL26A1, Hsap\COL11A2, Hsap\COL9A3, Hsap\COL23A1, Hsap\COL17A1, Hsap\COL20A1, Hsap\COL9A2, Hsap\COL4A4, Hsap\COL7A1, Hsap\COL19A1, Hsap\COL6A1, Hsap\COL24A1, Hsap\COL5A2, Hsap\COLQ, Hsap\COL1A1, Hsap\COL15A1, Hsap\COL11A1, Hsap\COL6A5, Hsap\COL3A1, Hsap\COL2A1, Hsap\COL4A3, Hsap\COL4A5, Hsap\COL22A1, Hsap\COL9A1, Hsap\COL25A1, Hsap\COL27A1, Hsap\VWA1, Hsap\COL4A1, Hsap\COL6A6" " embryonic stage | stage 15-16 , embryonic stage | stage 16-17 , larval stage | first instar " " embryonic/larval hemocyte

, embryonic/larval fat body

" " pupal stage | stage P6 , P | stage P5 " " leg & joint | distal

, leg & joint

" "viable,fertile,lethal,recessive,dominant,cold sensitive,heat sensitive,partially lethal - majority die,female sterile,locomotor behavior defective,partially,some die during embryonic stage,neuroanatomy defective,small body,lethal - all die before end of larval stage,some die during larval stage" "common oviduct circular muscle,heat sensitive,lateral oviduct circular muscle,ovarian basement membrane,mitochondrial membrane,intracellular membrane-bounded organelle,embryonic/larval cuticle,dorsal,head,embryonic/larval central nervous system,embryonic/larval brain,embryonic/larval optic lobe,muscle attachment site,apodeme,embryonic/larval somatic muscle,somatic muscle,leg & adult apodeme,embryonic/larval visceral muscle" DRSC03291 E 0.910765943 0.311758324 1.529056422 0.264942366 -0.362263233 -0.41093042 FBgn0033526 Caf1-105 "Chromatin assembly factor 1, p105 subunit" http://flybase.org/reports/FBgn0033526 protein_coding_gene DNA binding ; GO:0003677 | non-traceable author statement histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000392175 histone binding ; GO:0042393 | contributes_to inferred by curator from GO:0033186 nucleosome assembly ; GO:0006334 | inferred from direct assay positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype inferred from physical interaction with E(spl)mβ-HLH inferred from physical interaction with E(spl)mβ-HLH nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000392175 CAF-1 complex ; GO:0033186 | inferred from direct assay "p105, Caf1-10, CG12892, Caf1-105, caf1-105, CAF p105, CAF1-105, CAF1p105, CAF1-p75/p105, CAF1-p75, dCAF1-p75, CAF1-p105, dCAF1-p105, p75, p105/p75, p75/p105, CAF105/75, dCAF-1-p105, CAF1p75, Caf-105, P105" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site" CG12892 11-Aug-17 DroID_v2017_08 Drer\chaf1b Scer\CAC2 Cele\chaf-2 Xtro\chaf1b Mmus\Chaf1b "Hsap\CHAF1B, Hsap\HIRA, Hsap\C22orf39" "viable,fertile,lethal - all die before end of pupal stage,developmental rate defective,small body,visible,somatic clone - Minute background" "wing,somatic clone - Minute background,trichogen cell,eye" FBgn0020620 RN-tre Related to the N terminus of tre oncogene http://flybase.org/reports/FBgn0020620 FBgn0033892 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Evi5 "CG13351, DRN-tre, CG8085, RN-tre" IPR000195:Rab-GTPase-TBC domain CG8085 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-19e1.3, Drer\rabgap1l2, Drer\si:ch211-288d18.1, Drer\usp6nl, Drer\rabgap1l" "Scer\MSB4, Scer\MSB3, Scer\GYL1" Cele\tbc-17 Xtro\rabgap1l "Mmus\Rabgap1l, Mmus\Usp6nl, Mmus\Rabgap1" "Hsap\TBC1D3, Hsap\TBC1D28, Hsap\RABGAP1, Hsap\TBC1D3E, Hsap\USP6NL, Hsap\TBC1D3H, Hsap\TBC1D3L, Hsap\TBC1D29, Hsap\TBC1D3G, Hsap\TBC1D3I, Hsap\TBC1D3B, Hsap\TBC1D3C, Hsap\TBC1D3F, Hsap\TBC1D26, Hsap\RABGAP1L, Hsap\TBC1D3K, Hsap\USP6, Hsap\LOC101060389, Hsap\RNFT1" "neuroanatomy defective,viable,planar polarity defective,cell migration defective" "mushroom body & axon7B,Kenyon cell,adult mushroom body,mushroom body & axonc739,eye photoreceptor cell,eye,border follicle cell" FBgn0034118 Nup62 Nucleoporin 62kD http://flybase.org/reports/FBgn0034118 protein_coding_gene nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with SGD:S000003577 phospholipid binding ; GO:0005543 | inferred from biological aspect of ancestor with PANTHER:PTN000249931 chromatin DNA binding ; GO:0031490 | inferred from mutant phenotype structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000249931 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000249931 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000249931 karyosome formation ; GO:0030717 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q7K0D8 inferred from genetic interaction with UniProtKB:Q9V463 inferred from genetic interaction with UniProtKB:Q9VKJ3 inferred from genetic interaction with UniProtKB:Q9VWE6 RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000249931 regulation of nucleus size ; GO:0097298 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype chromosome attachment to the nuclear envelope ; GO:0097240 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q9V463 ribonucleoprotein complex export from nucleus ; GO:0071426 | inferred from biological aspect of ancestor with PANTHER:PTN000249931 nuclear envelope ; GO:0005635 | inferred from direct assay chromatin ; GO:0000785 | inferred from mutant phenotype nuclear pore central transport channel ; GO:0044613 | inferred from biological aspect of ancestor with PANTHER:PTN000249931 nuclear pore central transport channel ; GO:0044613 | inferred from sequence or structural similarity with SGD:S000003577 "p62, CG6251, Nup62" "IPR007758:Nucleoporin, NSP1-like, C-terminal, IPR026010:Nucleoporin NSP1/NUP62" CG6251 11-Aug-17 DroID_v2017_08 "Drer\nup62l, Drer\nup98, Drer\nup58" "Scer\NUP116, Scer\NSP1, Scer\NUP49, Scer\NUP145, Scer\NUP100" "Cele\npp-4, Cele\unc-14, Cele\npp-11, Cele\npp-10" Xtro\nup62 "Mmus\Nupl1, Mmus\Nup62cl, Mmus\Nup98, Mmus\Nup62" "Hsap\NUP58, Hsap\NUP62CL, Hsap\JAKMIP3, Hsap\NUP62, Hsap\NUP98" "viable,cell growth defective" DRSC06970 K -0.228288196 -0.076428078 0.362271102 1.230020171 -0.422605905 1.601713684 FBgn0028697 RpL15 Ribosomal protein L15 http://flybase.org/reports/FBgn0028697 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000439, InterPro:IPR012678, InterPro:IPR020925, InterPro:IPR024794 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000439, InterPro:IPR012678, InterPro:IPR020925 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000439, InterPro:IPR012678, InterPro:IPR020925, InterPro:IPR024794 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "lethal 2, l(3)80Fi, L15, CG40199, l2, l(3)Lh2, CG17420, RpL15, DmRpL15, 80Fi, RPL15" "IPR000439:Ribosomal protein L15e, IPR012678:Ribosomal protein L23/L15e core domain, IPR024794:Ribosomal protein L15e core domain, IPR020925:Ribosomal protein L15e, conserved site" CG17420 11-Aug-17 DroID_v2017_08 "Drer\ube2e1, Drer\rpl15, Drer\zgc:153668" "Scer\RPL15B, Scer\RPL15A" Cele\rpl-15 Xtro\rpl15 Mmus\Rpl15 Hsap\RPL15 "lethal,sterile,visible,partially,female,recessive,viable,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of larval stage,some die during larval stage,Minute,developmental rate defective,female sterile" "gonad,macrochaeta,eye,male genitalia,wing,wing vein,wing hair,chaeta,genitalia,sex comb,ommatidium,ovary" DRSC20963 E -0.974997666 -0.103730465 0.378107734 -3.069948573 1.358483941 1.364614045 FBgn0030365 Tango4 Transport and Golgi organization 4 http://flybase.org/reports/FBgn0030365 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000460428 protein secretion ; GO:0009306 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay Cul4-RING E3 ubiquitin ligase complex ; GO:0080008 | inferred from biological aspect of ancestor with PANTHER:PTN000460428 DNA replication factor A complex ; GO:0005662 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN000460428 cytosol ; GO:0005829 | inferred from direct assay Prp19 complex ; GO:0000974 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG1796, Tango4, TANGO4, tango4" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like" CG1796 11-Aug-17 DroID_v2017_08 Drer\plrg1 "Scer\PRP46, Scer\TUP1" Cele\plrg-1 Xtro\plrg1 Mmus\Plrg1 Hsap\PLRG1 viable DRSC19786 IK 0.152277484 2.029809526 -0.34221659 0.913388729 -1.793669698 0.179515033 FBgn0032013 Scgalpha Sarcoglycan alpha http://flybase.org/reports/FBgn0032013 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR015919 structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC:10805 inferred from sequence or structural similarity with HGNC:10808 muscle system process ; GO:0003012 | inferred from biological aspect of ancestor with PANTHER:PTN000805895 membrane organization ; GO:0061024 | inferred from biological aspect of ancestor with PANTHER:PTN000805895 sarcoglycan complex ; GO:0016012 | inferred from sequence or structural similarity with HGNC:10805 inferred from sequence or structural similarity with HGNC:10808 "CG7851, DmSCG-alphaepsilon, Scgalpha, Scga" "IPR015919:Cadherin-like, IPR006644:Dystroglycan-type cadherin-like, IPR008908:Sarcoglycan alpha/epsilon" CG7851 11-Aug-17 DroID_v2017_08 "Drer\sgca, Drer\sgce" - Cele\sgca-1 "Xtro\sgce, Xtro\sgca" "Mmus\Sgce, Mmus\Sgca" "Hsap\SGCE, Hsap\SGCA" viable FBgn0053801 His1:CG33801 His1:CG33801 http://flybase.org/reports/FBgn0053801 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33801, His1:CG33801" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33801 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-261m9.12, Drer\h1m, Drer\si:ch1073-159d7.7, Drer\si:dkey-108k21.10, Drer\si:ch211-113a14.24, Drer\zgc:163061, Drer\si:dkey-108k21.14, Drer\zgc:110216, Drer\zgc:110425, Drer\si:dkey-108k21.21, Drer\histh1l, Drer\h1fx, Drer\zgc:153405, Drer\si:ch73-36p18.1, Drer\h1f0" Scer\HHO1 "Cele\hil-3, Cele\his-24, Cele\hil-2, Cele\hil-5, Cele\hil-6, Cele\hil-4" Xtro\h1f0 "Mmus\Hist1h1b, Mmus\Hist1h1d, Mmus\Hist1h1a, Mmus\H1fnt, Mmus\Hist1h1c, Mmus\Hils1, Mmus\H1foo, Mmus\Hist1h1e, Mmus\Hist1h1t, Mmus\H1fx" "Hsap\H1F0, Hsap\HIST1H1B, Hsap\HIST1H1E, Hsap\HIST1H1T, Hsap\H1FOO, Hsap\H1FX, Hsap\H1FNT, Hsap\HIST1H1A, Hsap\HIST1H1D, Hsap\HIST1H1C" FBgn0034087 clu clueless http://flybase.org/reports/FBgn0034087 protein_coding_gene ribosome binding ; GO:0043022 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from direct assay intracellular distribution of mitochondria ; GO:0048312 | inferred from electronic annotation with InterPro:IPR027523 mitochondrion localization ; GO:0051646 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype inferred from genetic interaction with l(2)gl inferred from genetic interaction with park inferred from physical interaction with baz inferred from physical interaction with aPKC cytoplasm ; GO:0005737 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay outer mitochondrial membrane protein complex ; GO:0098799 | inferred from direct assay extrinsic component of mitochondrial outer membrane ; GO:0031315 | inferred from physical interaction with porin inferred from physical interaction with Tom20 "anon-WO0118547.143, clu, CG8443, Clu" "IPR025697:CLU domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR027523:Clustered mitochondria protein, IPR028275:Clustered mitochondria protein, N-terminal, IPR007967:Protein of unknown function DUF727, IPR011990:Tetratricopeptide-like helical domain, IPR023231:GSKIP domain, IPR033646:CLU central domain" CG8443 11-Aug-17 DroID_v2017_08 "Drer\LOC100150676, Drer\cluha, Drer\si:ch211-166a6.5" Scer\CLU1 Cele\clu-1 Xtro\cluh Mmus\Cluh Hsap\CLUH "viable,developmental rate defective,short lived,flightless,locomotor behavior defective,male sterile,female sterile,lethal,recessive,small body,uncoordinated,sterile,partially lethal - majority die,male semi-sterile,fertile,body color defective" "wing,mitochondrion,flight muscle,ovary,mitochondrial inner membrane,mitochondrial crista,female germline stem cell,embryonic/larval fat body,Nebenkern derivative,female germline cell,mesothoracic tergum" DRSC07181 E 0.375854713 -0.742597867 0.311038404 1.780487504 0.022580104 -0.120986793 FBgn0033644 Tret1-2 Trehalose transporter 1-2 http://flybase.org/reports/FBgn0033644 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 trehalose transmembrane transporter activity ; GO:0015574 | NOT inferred from direct assay glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 trehalose transport ; GO:0015771 | NOT inferred from direct assay hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829 membrane ; GO:0016020 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay" "Tret1-2, CG8234, DmTret1-2" "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG8234 11-Aug-17 DroID_v2017_08 "Drer\LOC101882338, Drer\slc2a13b, Drer\slc2a6, Drer\slc2a10, Drer\si:dkey-229d11.5, Drer\si:ch1073-263o8.2, Drer\slc2a12, Drer\LOC797974, Drer\slc2a8" "Scer\GAL2, Scer\HXT1, Scer\VBA2, Scer\HXT16, Scer\HXT7, Scer\AZR1, Scer\SGE1, Scer\RGT2, Scer\MAL31, Scer\ITR2, Scer\HXT8, Scer\YMR279C, Scer\ATR1, Scer\HXT3, Scer\HXT13, Scer\HXT6, Scer\MAL11, Scer\VBA5, Scer\ENB1, Scer\ITR1, Scer\VBA1, Scer\STL1, Scer\HXT11, Scer\HXT17, Scer\HXT2, Scer\VBA4, Scer\HXT4, Scer\VBA3, Scer\HXT10, Scer\HXT15, Scer\YDR387C, Scer\MPH3, Scer\YFL040W, Scer\YDL199C, Scer\GEX1, Scer\HXT9, Scer\GEX2, Scer\HXT14, Scer\MPH2, Scer\SNF3, Scer\HXT5" "Cele\M01G12.14, Cele\hmit-1.2, Cele\M01G12.9, Cele\hmit-1.1, Cele\Y66D12A.21, Cele\hmit-1.3, Cele\ZK829.9" "Xtro\slc2a12, Xtro\slc2a10, Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a5" "Mmus\Gm7257, Mmus\Slc2a6, Mmus\Slc2a10, Mmus\Slc2a12, Mmus\Gm17689, Mmus\Slc2a13, Mmus\Slc2a8, Mmus\Tm2d1, Mmus\Pate4, Mmus\1700013H16Rik, Mmus\Acrv1, Mmus\Gm5615, Mmus\Pate1, Mmus\Slc2a5, Mmus\Pate3" "Hsap\SLC2A10, Hsap\SLC2A5, Hsap\ACRV1, Hsap\SLC2A8, Hsap\PATE3, Hsap\SLC2A6, Hsap\SLC2A13, Hsap\PATE4, Hsap\SLC2A12, Hsap\PATE1, Hsap\TM2D1" viable FBgn0050100 CG30100 - http://flybase.org/reports/FBgn0050100 protein_coding_gene translation release factor activity ; GO:0003747 | inferred from electronic annotation with InterPro:IPR000352 translational termination ; GO:0006415 | inferred from electronic annotation with InterPro:IPR000352 - "CG30100, Dromel_CG30100_FBtr0087140_mORF" IPR000352:Peptide chain release factor class I/class II CG30100 11-Aug-17 DroID_v2017_08 "Drer\mtrf1l, Drer\si:ch211-275j6.5" "Scer\MRF1, Scer\YLR281C" Cele\T23B5.4 "Xtro\mtrf1l, Xtro\mtrf1" "Mmus\Mtrf1, Mmus\2810006K23Rik, Mmus\Mtrf1l" "Hsap\MTRF1L, Hsap\C12orf65, Hsap\MTRF1" "viable,fertile" FBgn0250791 alphaSnap alpha Soluble NSF attachment protein http://flybase.org/reports/FBgn0250791 protein_coding_gene "soluble NSF attachment protein activity ; GO:0005483 | inferred from direct assay soluble NSF attachment protein activity ; GO:0005483 | inferred from physical interaction with Syx5, Syx1A, Syx16 ATPase activator activity ; GO:0001671 | inferred from sequence or structural similarity with SGD:S000000146 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 soluble NSF attachment protein activity ; GO:0005483 | non-traceable author statement SNARE binding ; GO:0000149 | inferred from physical interaction with Syx5 SNARE binding ; GO:0000149 | inferred from physical interaction with Syx5, Syx1A, Syx16" chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype protein homooligomerization ; GO:0051260 | inferred from direct assay intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from mutant phenotype synaptic vesicle priming ; GO:0016082 | non-traceable author statement neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from expression pattern protein hexamerization ; GO:0034214 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | non-traceable author statement intracellular protein transport ; GO:0006886 | inferred from mutant phenotype imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype SNARE complex disassembly ; GO:0035494 | inferred from direct assay synaptic vesicle fusion to presynaptic active zone membrane ; GO:0031629 | inferred from direct assay SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay vacuolar membrane ; GO:0005774 | inferred from biological aspect of ancestor with PANTHER:PTN000349241 terminal bouton ; GO:0043195 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay axon terminus ; GO:0043679 | inferred from direct assay "alpha-Snap, SNAP, alpha-SNAP, dSNAP, dalpha-SNAP, dsnap, CG6625, alphaSnap, dalphaSNAP, snap, l(3)77ABc, l(3)77ABa, Snap, aSnap" "IPR000744:NSF attachment protein, IPR011990:Tetratricopeptide-like helical domain" CG6625 11-Aug-17 DroID_v2017_08 "Drer\zgc:158643, Drer\napab, Drer\si:rp71-81o21.2, Drer\napaa, Drer\napba" Scer\SEC17 Cele\snap-1 "Xtro\napb, Xtro\napa" "Mmus\Napa, Mmus\Napb" "Hsap\NAPA, Hsap\NAPB" " larval stage , embryonic stage | late , adult stage " embryonic central nervous system

DRSC11285 IEK -1.184151058 1.610543437 -0.827370986 -3.334247002 -2.858081866 -1.993764221 FBgn0044048 Ilp5 Insulin-like peptide 5 http://flybase.org/reports/FBgn0044048 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 sleep ; GO:0030431 | inferred from mutant phenotype regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from biological aspect of ancestor with PANTHER:PTN001414741 insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype female mating behavior ; GO:0060180 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | NOT inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "dILP-5, dilp5, DILP, dilp, dilp-5, Dilp, Dilp 5, DILP5, CG33273, Ilp5, Ilp, Dilp-5, Dilp5, ilp5, dILP5, Ilp-5, ILP5, dIlp5, DILP-5, dipl5" "IPR016179:Insulin-like, IPR022352:Insulin family, IPR022353:Insulin, conserved site" CG33273 11-Aug-17 DroID_v2017_08 "Drer\ins, Drer\insb" - Cele\ins-1 - "Mmus\Ins2, Mmus\Ins1" Hsap\INS-IGF2 " larval stage | third instar , larval stage | third instar stage 2 " " embryonic/larval midgut

, larval brain | restricted

anterior & medial , larval brain | restricted

" "large body,chemical resistant,long lived,viable,mating defective,sleep defective" embryonic/larval neuroblast FBgn0051522 CG31522 - http://flybase.org/reports/FBgn0051522 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "CG9798, BcDNA:LD10305, BcDNA:GH22993, anon-WO0118547.381, CG31522" IPR002076:ELO family CG31522 11-Aug-17 DroID_v2017_08 "Drer\elovl1a, Drer\elovl7b, Drer\elovl8b, Drer\elovl8a, Drer\elovl4a, Drer\elovl4b, Drer\elovl2, Drer\elovl7a, Drer\elovl5, Drer\elovl1b" "Scer\ELO1, Scer\ELO2, Scer\ELO3" "Cele\elo-7, Cele\elo-6, Cele\elo-1" "Xtro\elovl1, Xtro\elovl7, Xtro\elovl2, Xtro\elovl5" "Mmus\Elovl7, Mmus\Elovl4, Mmus\Elovl2, Mmus\Elovl5, Mmus\Elovl1" "Hsap\ELOVL4, Hsap\ELOVL7, Hsap\ELOVL2, Hsap\ELOVL5, Hsap\ELOVL1" viable FBgn0034172 CG6665 - http://flybase.org/reports/FBgn0034172 protein_coding_gene - - - CG6665 IPR010876:NICE-3 predicted CG6665 11-Aug-17 DroID_v2017_08 Drer\zgc:123238 - Cele\Y51F10.11 Xtro\c1orf43 Mmus\4933434E20Rik Hsap\C1orf43 viable FBgn0262732 mbf1 multiprotein bridging factor 1 http://flybase.org/reports/FBgn0262732 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001387 transcription coactivator activity ; GO:0003713 | inferred from direct assay protein binding, bridging ; GO:0030674 | inferred from physical interaction with Tbp, apt" central nervous system development ; GO:0007417 | inferred from mutant phenotype inferred from genetic interaction with apt open tracheal system development ; GO:0007424 | inferred from mutant phenotype inferred from genetic interaction with apt dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "mbf1, MBF-1, MBF1, BcDNA:GM01267, CG4143, BcDNA:GH10148, Mbf1, MRE4, Mbf-1" "IPR001387:Cro/C1-type helix-turn-helix domain, IPR010982:Lambda repressor-like, DNA-binding domain, IPR013729:Multiprotein bridging factor 1, N-terminal" CG4143 11-Aug-17 DroID_v2017_08 Drer\edf1 Scer\MBF1 Cele\mbf-1 Xtro\edf1 Mmus\Edf1 Hsap\EDF1 FBgn0020249 stck steamer duck http://flybase.org/reports/FBgn0020249 FBgn0026191 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with msn apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype cell leading edge ; GO:0031252 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from direct assay "PINCH, dPINCH, pinch, pin85A, D-PINCH, dpin, stk, CG7954, stck, Pinch" "IPR001781:Zinc finger, LIM-type, IPR017351:LIM and senescent cell antigen-like-containing domain protein 1" CG7954 11-Aug-17 DroID_v2017_08 "Drer\lims2, Drer\zyx, Drer\lims1" "Scer\LRG1, Scer\PXL1" "Cele\pin-2, Cele\unc-97" Xtro\lims1 "Mmus\Lims2, Mmus\Lims1" "Hsap\LIMS1, Hsap\LIMS2, Hsap\DMTN, Hsap\LIMS4, Hsap\LIMS3" " embryonic stage | stage 16 , embryonic stage | stage 13 , embryonic stage | stage 10 " " visceral mesoderm

, muscle attachment site

, mesoderm

" "visible,viable,lethal,recessive,hypoactive,somatic clone,lethal - all die before end of larval stage,some die during larval stage" "wing,somatic clone,embryonic/larval somatic muscle,larva,embryonic somatic muscle,myofibril & actin filament097),embryonic/first instar larval cuticle,dorsal,germline clone,embryonic head" FBgn0053180 Ranbp16 Ranbp16 http://flybase.org/reports/FBgn0053180 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from biological aspect of ancestor with PANTHER:PTN000287688 nuclear export signal receptor activity ; GO:0005049 | inferred from biological aspect of ancestor with PANTHER:PTN000287688 nuclear export signal receptor activity ; GO:0005049 | inferred from sequence or structural similarity with UniProtKB:Q9UIA9 protein export from nucleus ; GO:0006611 | inferred from biological aspect of ancestor with PANTHER:PTN000287688 protein export from nucleus ; GO:0006611 | inferred from sequence or structural similarity with UniProtKB:Q9UIA9 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9UIA9 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9UIA9 nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN000287688 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000287688 nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with UniProtKB:Q9UIA9 "CG9126, RanBP16, CG9136, CG33180, Ranbp16" "IPR001494:Importin-beta, N-terminal domain, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG33180 11-Aug-17 DroID_v2017_08 Drer\xpo7 - Cele\C35A5.8 Xtro\xpo7 "Mmus\Ranbp17, Mmus\Xpo7" "Hsap\RANBP17, Hsap\XPO7" FBgn0033038 CG7791 - http://flybase.org/reports/FBgn0033038 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity with UniProtKB:Q99797 metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000211184 protein processing involved in protein targeting to mitochondrion ; GO:0006627 | inferred from biological aspect of ancestor with PANTHER:PTN000928390 protein processing ; GO:0016485 | inferred from sequence or structural similarity with UniProtKB:Q99797 peptide metabolic process ; GO:0006518 | inferred from biological aspect of ancestor with PANTHER:PTN000211184 mitochondrial matrix ; GO:0005759 | inferred from electronic annotation with InterPro:IPR033851 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000211186 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q99797 CG7791 "IPR001567:Peptidase M3A/M3B catalytic domain, IPR033851:Mitochondrial intermediate peptidase, IPR024080:Neurolysin/Thimet oligopeptidase, N-terminal" CG7791 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-1a9.4, Drer\mipep" "Scer\PRD1, Scer\OCT1" "Cele\ZK550.3, Cele\Y67H2A.7" Xtro\mipep "Mmus\Frem2, Mmus\Thop1, Mmus\Mipep" "Hsap\THOP1, Hsap\FREM2, Hsap\MIPEP" "viable,visible" trichogen cell FBgn0262081 Csk C-terminal Src kinase http://flybase.org/reports/FBgn0262081 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357" establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype positive regulation of programmed cell death ; GO:0043068 | inferred from mutant phenotype epithelial structure maintenance ; GO:0010669 | inferred from mutant phenotype transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 adherens junction maintenance ; GO:0034334 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from direct assay peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein phosphorylation ; GO:0006468 | non-traceable author statement negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from mutant phenotype inferred from genetic interaction with bsk inferred from genetic interaction with ena inferred from genetic interaction with tsr inferred from genetic interaction with tum inferred from genetic interaction with zip germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from genetic interaction with Src64B inferred from genetic interaction with Src42A regulation of synaptic plasticity ; GO:0048167 | inferred from genetic interaction with GluRIIA inferred from genetic interaction with FLYBASE:GluRIinferred by curator; FB:FBgn0046113 inferred from genetic interaction with cac cell-cell junction ; GO:0005911 | inferred from sequence or structural similarity with MGI:MGI:88537 extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 "csk, Csk, dCsk, CG42317, DCsk, dcsk, dCSK, CSK, CG17309, l(3)S017909, l(3)j1D8, CG32852, flik, d-Csk" "IPR011009:Protein kinase-like domain, IPR008266:Tyrosine-protein kinase, active site, IPR000980:SH2 domain, IPR000719:Protein kinase domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG42317 11-Aug-17 DroID_v2017_08 "Drer\txk, Drer\zgc:194282, Drer\abl2, Drer\jak2b, Drer\csk, Drer\abl1, Drer\itk, Drer\fynb, Drer\si:ch211-167j9.5, Drer\src, Drer\lyn, Drer\matk, Drer\styk1, Drer\jak3, Drer\hck, Drer\yes1, Drer\lck, Drer\si:ch73-340m8.2, Drer\jak1, Drer\fyna, Drer\btk, Drer\frk, Drer\ptk6b, Drer\ptk6a, Drer\jak2a" - "Cele\csk-1, Cele\K09B11.5, Cele\T25B9.5, Cele\aap-1, Cele\Y69E1A.3, Cele\nipi-4, Cele\Y52D5A.2, Cele\kin-21" "Xtro\fyn, Xtro\jak3, Xtro\csk, Xtro\jak2, Xtro\lyn, Xtro\abl2, Xtro\lck, Xtro\src, Xtro\tec, Xtro\yes1, Xtro\tyk2, Xtro\btk, Xtro\fgr, Xtro\jak1" "Mmus\Txk, Mmus\Abl1, Mmus\Bmx, Mmus\Ptk6, Mmus\Fyn, Mmus\Fgr, Mmus\Yes1, Mmus\Jak3, Mmus\Jak1, Mmus\Tyk2, Mmus\Jak2, Mmus\Itk, Mmus\Abl2, Mmus\Csk, Mmus\Lyn, Mmus\Tec, Mmus\Frk, Mmus\Lck, Mmus\Hck, Mmus\Btk, Mmus\Srms, Mmus\Src, Mmus\Blk, Mmus\Matk" "Hsap\BTK, Hsap\SRC, Hsap\ABL2, Hsap\FRK, Hsap\SRMS, Hsap\LCK, Hsap\JAK3, Hsap\MATK, Hsap\TEC, Hsap\HCK, Hsap\TXK, Hsap\PTK6, Hsap\TYK2, Hsap\FGR, Hsap\BLK, Hsap\YES1, Hsap\ITK, Hsap\CSK, Hsap\ABL1, Hsap\JAK1, Hsap\BMX, Hsap\FYN, Hsap\JAK2, Hsap\LYN" pupal stage salivary gland

DRSC23272 K -0.769165116 -0.503492429 -0.177355526 -0.584595293 -0.492363755 1.755578359 FBgn0030789 Rrp45 Rrp45 http://flybase.org/reports/FBgn0030789 protein_coding_gene - RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR033100 exosome (RNase complex) ; GO:0000178 | inferred from direct assay exosome (RNase complex) ; GO:0000178 | inferred from sequence or structural similarity with SGD:S000002688 "CG9606, dRrp45, Rrp45, rrp45" "IPR001247:Exoribonuclease, phosphorolytic domain 1, IPR015847:Exoribonuclease, phosphorolytic domain 2, IPR027408:PNPase/RNase PH domain, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR033100:Exosome complex component RRP45" CG9606 11-Aug-17 DroID_v2017_08 "Drer\exosc8, Drer\exosc9" Scer\RRP45 Cele\exos-9 Xtro\exosc9 "Mmus\Exosc8, Mmus\Exosc9" "Hsap\EXOSC9, Hsap\EXOSC8" "lethal,recessive,viable" FBgn0033792 CG13325 - http://flybase.org/reports/FBgn0033792 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG13325 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG13325 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-32, Cele\oac-6, Cele\oac-20, Cele\oac-53, Cele\oac-3, Cele\oac-31, Cele\oac-7, Cele\oac-55, Cele\oac-14, Cele\oac-39, Cele\ndg-4, Cele\nrf-6, Cele\rhy-1, Cele\oac-9, Cele\oac-5, Cele\oac-46, Cele\oac-50, Cele\oac-54" Xtro\LOC101732251 Mmus\Oacyl - "viable,fertile" FBgn0036603 CG13062 - http://flybase.org/reports/FBgn0036603 protein_coding_gene - - - CG13062 IPR007614:Retinin-like protein CG13062 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0083941 CG34105 - http://flybase.org/reports/FBgn0083941 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34105 - CG34105 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038976 Pfdn5 Prefoldin 5 http://flybase.org/reports/FBgn0038976 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR011599 "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR011599 regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000975547" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000975547 prefoldin complex ; GO:0016272 | colocalizes_with inferred from direct assay prefoldin complex ; GO:0016272 | inferred from direct assay "CG7048, Pfdn5, pfdn5" "IPR004127:Prefoldin alpha-like, IPR011599:Prefoldin alpha subunit, archaea-type" CG7048 11-Aug-17 DroID_v2017_08 Drer\pfdn5 Scer\GIM5 "Cele\pfd-5, Cele\F35H10.6" Xtro\pfdn5 Mmus\Pfdn5 Hsap\PFDN5 "lethal,viable,visible" "embryonic/larval brain,trichogen cell" FBgn0014033 Sr-CI "Scavenger receptor class C, type I" http://flybase.org/reports/FBgn0014033 - protein_coding_gene polysaccharide binding ; GO:0030247 | inferred from electronic annotation with InterPro:IPR001212 scavenger receptor activity ; GO:0005044 | inferred from electronic annotation with InterPro:IPR001212 scavenger receptor activity ; GO:0005044 | traceable author statement polysaccharide binding ; GO:0030247 | traceable author statement immune response ; GO:0006955 | inferred from electronic annotation with InterPro:IPR001212 phagocytosis ; GO:0006909 | traceable author statement response to bacterium ; GO:0009617 | traceable author statement immune response ; GO:0006955 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000998 "dSR-CI, Sr-Cl, dSR-C1, D-SR-CI, dSRC-I, SR-CI, DSR-CI, dScR-I, CT9876, CG4099, Sr-CI, SR-C1, Sr-C1" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR000436:Sushi/SCR/CCP domain, IPR000998:MAM domain, IPR001212:Somatomedin B domain" CG4099 11-Aug-17 DroID_v2017_08 "Drer\mamdc1, Drer\wu:fb63a08, Drer\mep1a.2, Drer\mep1a.1, Drer\malrd1, Drer\si:ch73-40a17.3, Drer\mep1b" - - Xtro\mdga2 "Mmus\Cd55b, Mmus\Cd55, Mmus\Mamdc2, Mmus\Mdga1, Mmus\Malrd1, Mmus\Mdga2" "Hsap\MDGA1, Hsap\MALRD1, Hsap\MDGA2, Hsap\MAMDC2" embryonic stage " embryonic/larval hemocyte

, macrophage

" viable DRSC23942 K -0.698943034 -0.415570321 0.685909403 -0.281510956 1.732215836 -0.032793406 FBgn0036004 Jarid2 "Jumonji, AT rich interactive domain 2" http://flybase.org/reports/FBgn0036004 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001606, InterPro:IPR017956" regulation of histone H3-K27 methylation ; GO:0061085 | inferred from mutant phenotype nuclear euchromatin ; GO:0005719 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay ESC/E(Z) complex ; GO:0035098 | inferred from direct assay "Jarid2, CG3654, dJARID2, djmj, dJmj, JARID2" "IPR001606:ARID DNA-binding domain, IPR003347:JmjC domain, IPR003349:JmjN domain, IPR004198:Zinc finger, C5HC2-type" CG3654 11-Aug-17 DroID_v2017_08 "Drer\jarid2b, Drer\kdm5a, Drer\kdm6a, Drer\kdm5c, Drer\kdm5bb, Drer\kdm6al, Drer\jarid2a, Drer\kdm5ba" "Scer\ECM5, Scer\JHD2" Cele\rbr-2 "Xtro\kdm6b, Xtro\kdm5b, Xtro\kdm5a, Xtro\kdm5c, Xtro\kdm6a, Xtro\jarid2" "Mmus\Kdm5a, Mmus\Kdm6a, Mmus\Uty, Mmus\Jarid2, Mmus\Kdm6b, Mmus\Kdm5b, Mmus\Kdm5c, Mmus\Kdm5d" "Hsap\KDM5A, Hsap\KDM6B, Hsap\KDM5B, Hsap\UTY, Hsap\JARID2, Hsap\KDM6A, Hsap\KDM5C, Hsap\KDM5D" "viable,suppressor of variegation,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,fertile,visible,dominant" "polytene chromosome,leg,embryonic/larval hemocyte | third instar larval stage,wing vein,ectopic" FBgn0030366 Usp7 Ubiquitin-specific protease 7 http://flybase.org/reports/FBgn0030366 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with UniProtKB:Q93009 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 histone deubiquitination ; GO:0016578 | inferred from direct assay chromatin silencing ; GO:0006342 | inferred from genetic interaction with Pc protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with UniProtKB:Q93009 polytene chromosome ; GO:0005700 | inferred from direct assay transcriptionally silent chromatin ; GO:0035328 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q93009 protein complex ; GO:0043234 | inferred from physical interaction with bur nucleus ; GO:0005634 | inferred from direct assay "CG1490, Usp7, USP7, Usp-7, Q9VYQ8" "IPR018200:Ubiquitin specific protease, conserved site, IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR002083:MATH/TRAF domain, IPR008974:TRAF-like, IPR024729:Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain, IPR028889:Ubiquitin specific protease domain, IPR029346:Ubiquitin carboxyl-terminal hydrolase, C-terminal" CG1490 11-Aug-17 DroID_v2017_08 "Drer\usp25, Drer\usp28, Drer\usp40, Drer\usp18, Drer\usp48, Drer\usp7, Drer\fbxl6" "Scer\UBP2, Scer\UBP15" "Cele\math-33, Cele\usp-39" "Xtro\usp25, Xtro\usp40, Xtro\usp7, Xtro\usp28" "Mmus\Usp7, Mmus\Usp25, Mmus\Usp28, Mmus\Usp18, Mmus\Usp48, Mmus\Usp40" "Hsap\USP7, Hsap\USP48, Hsap\USP40, Hsap\USP28, Hsap\USP25, Hsap\USP18" "short lived,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,sterile,lethal,male,body color defective,partially lethal - majority die,visible" "wing,mesothoracic tergum,scutellar bristle" FBgn0036136 Ufd1-like Ubiquitin fusion-degradation 1-like http://flybase.org/reports/FBgn0036136 protein_coding_gene - proteolysis ; GO:0006508 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from mutant phenotype cellular response to virus ; GO:0098586 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from mutant phenotype proteasome complex ; GO:0000502 | non-traceable author statement "Udf1, CG6233, anon-WO0118547.405, Ufd1-like, Ufd1, dUfd1, ufd1-like, UFD1, Ufd-1, UfD1-like, Ufd1L, Ufd1 like, dUFD1L, ufd1" IPR004854:Ubiquitin fusion degradation protein UFD1 CG6233 11-Aug-17 DroID_v2017_08 Drer\ufd1l Scer\UFD1 Cele\ufd-1 Xtro\ufd1l Mmus\Ufd1l Hsap\UFD1L "viable,stress response defective" DRSC10607 K -0.616787643 0.046258163 -0.651692926 0.514236777 1.92313747 0.811263903 FBgn0034710 CG3292 - http://flybase.org/reports/FBgn0034710 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG3292 "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG3292 11-Aug-17 DroID_v2017_08 "Drer\alpl, Drer\alpi.1, Drer\alpi.2, Drer\alp3" Scer\PHO8 - "Xtro\alpi.1, Xtro\alpl" "Mmus\Alpl, Mmus\Alppl2, Mmus\Alpi, Mmus\Akp3" "Hsap\ALPI, Hsap\ALPPL2, Hsap\ALPL, Hsap\ALPP" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0028658 Adat1 "Adenosine deaminase, tRNA-specific 1" http://flybase.org/reports/FBgn0028658 protein_coding_gene tRNA-specific adenosine deaminase activity ; GO:0008251 | inferred from sequence or structural similarity RNA binding ; GO:0003723 | inferred from mutant phenotype tRNA-specific adenosine deaminase activity ; GO:0008251 | inferred from direct assay tRNA modification ; GO:0006400 | inferred from direct assay tRNA processing ; GO:0008033 | inferred from mutant phenotype - "dADAT1, BG:DS00941.2, CG16889, Adat, Adat1, adat" IPR002466:Adenosine deaminase/editase CG16889 11-Aug-17 DroID_v2017_08 "Drer\adarb1a, Drer\adarb2, Drer\zgc:101765, Drer\adat1, Drer\zgc:110782, Drer\adad1, Drer\adarb1b, Drer\zgc:110366, Drer\adar, Drer\adad2" Scer\TAD1 "Cele\ZK1290.5, Cele\C35D10.6, Cele\C01G5.5, Cele\F53F1.2, Cele\adr-2, Cele\F53F1.3, Cele\K07C5.2" "Xtro\adar, Xtro\adarb2, Xtro\adad1, Xtro\adat1, Xtro\LOC548351, Xtro\adarb1" "Mmus\Adarb1, Mmus\Adad1, Mmus\Adat1, Mmus\Adad2, Mmus\Adar, Mmus\Adarb2" "Hsap\ADARB2, Hsap\ADAD2, Hsap\ADARB1, Hsap\ADAT1, Hsap\ADAR, Hsap\ADAD1" " embryonic stage | stage 8-12 , embryonic stage | stage >12 , embryonic stage | early " " ventral neurogenic region

, embryonic central nervous system

, mesoderm

, embryonic brain

, ventral nerve cord

" "partially lethal - majority die,some die during pupal stage" FBgn0065724 l(2)SH0563 lethal (2) SH0563 http://flybase.org/reports/FBgn0065724 gene - - - "l(2)SH0563, l(2)SH2 0563" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0036287 CG10663 - http://flybase.org/reports/FBgn0036287 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP30, CT29868, CG10663" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG10663 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.9, Drer\hp, Drer\si:dkey-21e2.12, Drer\gzm3, Drer\corin, Drer\wu:fd46c06, Drer\si:ch211-165b19.8, Drer\si:dkey-78l4.6" - "Cele\try-1, Cele\svh-1" Xtro\corin "Mmus\Gzme, Mmus\Try10, Mmus\Elane, Mmus\Corin, Mmus\C1rl, Mmus\Hp" "Hsap\HP, Hsap\PRSS1, Hsap\CORIN, Hsap\HPR, Hsap\GZMB, Hsap\CELA3A" "viable,fertile" FBgn0027601 pdgy pudgy http://flybase.org/reports/FBgn0027601 - protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 fatty acid catabolic process ; GO:0009062 | inferred from direct assay acyl-CoA biosynthetic process ; GO:0071616 | inferred from direct assay negative regulation of insulin receptor signaling pathway ; GO:0046627 | inferred from direct assay triglyceride catabolic process ; GO:0019433 | inferred from direct assay - "BcDNA:GH02901, CG9009, pdgy" "IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site" CG9009 11-Aug-17 DroID_v2017_08 "Drer\acsf2, Drer\acsf3" Scer\PCS60 "Cele\acs-9, Cele\acs-2, Cele\acs-10, Cele\acs-16, Cele\acs-21, Cele\acs-1, Cele\acs-7, Cele\acs-11, Cele\acs-14, Cele\acs-12, Cele\acs-6" Xtro\acsf3 "Mmus\Acsf2, Mmus\Acsf3" "Hsap\ACSF2, Hsap\ACSF3" "viable,fertile,long lived,nutrition conditional,small body" FBgn0051812 CG31812 - http://flybase.org/reports/FBgn0051812 protein_coding_gene tRNA-intron endonuclease activity ; GO:0000213 | inferred from biological aspect of ancestor with PANTHER:PTN000477043 tRNA-type intron splice site recognition and cleavage ; GO:0000379 | inferred from biological aspect of ancestor with PANTHER:PTN000477043 tRNA-intron endonuclease complex ; GO:0000214 | inferred from biological aspect of ancestor with PANTHER:PTN000477043 CG31812 "IPR006677:tRNA intron endonuclease, catalytic domain-like, IPR006676:tRNA-splicing endonuclease, IPR006678:tRNA intron endonuclease, N-terminal" CG31812 11-Aug-17 DroID_v2017_08 Drer\tsen2 Scer\SEN2 Cele\tsen-2 - Mmus\Tsen2 Hsap\TSEN2 "viable,visible" trichogen cell FBgn0005593 RpL7 Ribosomal protein L7 http://flybase.org/reports/FBgn0005593 FBgn0043838 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "pupariation ; GO:0035073 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000463 | inferred from biological aspect of ancestor with PANTHER:PTN000897517" cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "L7, CG4897, BEST:GH04411, RpL7, RPL7, Rp L7, rpl7, rpL7" "IPR018038:Ribosomal protein L30, conserved site, IPR005998:Ribosomal protein L7, eukaryotic, IPR012988:Ribosomal protein L30, N-terminal, IPR016082:Ribosomal protein L30, ferredoxin-like fold domain" CG4897 11-Aug-17 DroID_v2017_08 "Drer\rpl7l1, Drer\rpl7" "Scer\RPL7A, Scer\RLP7, Scer\RPL7B" Cele\rpl-7 Xtro\rpl7 "Mmus\Rpl7, Mmus\Npsr1, Mmus\Rpl7l1" "Hsap\NPSR1, Hsap\RPL7, Hsap\RPL7L1" "lethal,developmental rate defective" DRSC03417 IEK -3.196714529 -2.030824173 -0.053688902 -4.084685646 2.044770262 4.32480862 FBgn0021767 org-1 optomotor-blind-related-gene-1 http://flybase.org/reports/FBgn0021767 FBgn0024203 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" somatic muscle development ; GO:0007525 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR018186 nucleus ; GO:0005634 | inferred by curator from GO:0045944" "CG11202, org-1, Dm-ORG-1, Org-1" "IPR018186:Transcription factor, T-box, conserved site, IPR001699:Transcription factor, T-box, IPR008967:p53-like transcription factor, DNA-binding, IPR020683:Ankyrin repeat-containing domain" CG11202 11-Aug-17 DroID_v2017_08 "Drer\tbx3b, Drer\tbx2a, Drer\tbx16, Drer\tbx18, Drer\grap2b, Drer\tbx15, Drer\tbx5a, Drer\tbx2b, Drer\tbx22, Drer\tbx20, Drer\tbx1, Drer\tbx6, Drer\tbx5b, Drer\tbx3a" - "Cele\tbx-32, Cele\mab-9, Cele\tbx-38, Cele\tbx-34, Cele\mls-1, Cele\tbx-2, Cele\tbx-41, Cele\tbx-37, Cele\ZK328.6, Cele\tbx-35, Cele\tbx-31" "Xtro\mga, Xtro\tbx4, Xtro\tbx18, Xtro\tbx1, Xtro\tbx22, Xtro\tbx3, Xtro\tbx5, Xtro\tbx20, Xtro\tbx2, Xtro\tbx15, Xtro\vegt" "Mmus\Tbx20, Mmus\Tbx1, Mmus\Mga, Mmus\Tbx3, Mmus\Tbx10, Mmus\Tbx18, Mmus\Tbx15, Mmus\Tbx22, Mmus\Tbx5, Mmus\Tbx2, Mmus\Tbx4" "Hsap\TBX3, Hsap\TBX4, Hsap\TBX15, Hsap\TBX10, Hsap\TBX18, Hsap\TBX20, Hsap\TBX22, Hsap\TBX5, Hsap\TBX1, Hsap\TBX2" "lethal,visible,partially lethal - majority die,some die during pupal stage" "A1-7 lateral oblique muscle 1,A1-7 segment border muscle,A2-7 ventral transverse muscle 1,embryonic/larval alary muscle,abdominal lateral adult muscle precursor cell,embryonic/larval somatic muscle,eye,antenna,third segment of antenna,macrochaeta,ectopic,arista,unguis,interommatidial bristle,tarsal segment,ommatidium,supernumerary,trichogen cell,tormogen cell" FBgn0058160 CG40160 - http://flybase.org/reports/FBgn0058160 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" extracellular region ; GO:0005576 | inferred from direct assay "BcDNA:LD13269, CG40160" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG40160 11-Aug-17 DroID_v2017_08 "Drer\zgc:92745, Drer\zgc:112302, Drer\si:dkey-57c15.4, Drer\zgc:112368, Drer\zgc:92511, Drer\zgc:92041" - Cele\try-1 - "Mmus\Klk11, Mmus\Klkb1, Mmus\Klk1b26, Mmus\Klk1b27, Mmus\Egfbp2, Mmus\Klk1b22, Mmus\Klk1, Mmus\Klk1b9, Mmus\Klk1b8, Mmus\F11, Mmus\Klk1b24, Mmus\Klk1b11, Mmus\Klk1b3, Mmus\Klk1b1, Mmus\Klk1b21, Mmus\Klk1b5, Mmus\Ctrl, Mmus\Klk1b16, Mmus\Klk1b4" "Hsap\KLK11, Hsap\TPSAB1, Hsap\KLK3, Hsap\KLKB1, Hsap\KLK1, Hsap\KLK2, Hsap\F9, Hsap\F11" FBgn0000454 Dip-B Dipeptidase B http://flybase.org/reports/FBgn0000454 FBgn0038184 protein_coding_gene metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356 tripeptidyl-peptidase activity ; GO:0008240 | inferred from direct assay dipeptidyl-peptidase activity ; GO:0008239 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "CG9285, DipB, Dip-B" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG9285 11-Aug-17 DroID_v2017_08 "Drer\lap3, Drer\npepl1, Drer\zgc:152830" - "Cele\lap-2, Cele\lap-1" Xtro\lap3 "Mmus\Lap3, Mmus\Npepl1" "Hsap\NPEPL1, Hsap\LAP3" "viable,fertile,electrophoretic variant" FBgn0263855 BubR1 Bub1-related kinase http://flybase.org/reports/FBgn0263855 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from biological aspect of ancestor with PANTHER:PTN000361607 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271 regulation of exit from mitosis ; GO:0007096 | inferred from mutant phenotype inferred from genetic interaction with dup mitotic spindle assembly checkpoint ; GO:0007094 | inferred from sequence or structural similarity mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement synaptonemal complex organization ; GO:0070193 | inferred from mutant phenotype female meiosis sister chromatid cohesion ; GO:0007066 | inferred from mutant phenotype male meiosis sister chromatid cohesion ; GO:0007065 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from mutant phenotype meiotic sister chromatid cohesion, centromeric ; GO:0051754 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype regulation of mitotic sister chromatid separation ; GO:0010965 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | traceable author statement" kinetochore ; GO:0000776 | inferred from direct assay kinetochore ; GO:0000776 | traceable author statement kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay condensed chromosome outer kinetochore ; GO:0000940 | non-traceable author statement condensed nuclear chromosome kinetochore ; GO:0000778 | inferred from biological aspect of ancestor with PANTHER:PTN000361607 "BubR1, CG7838, bubr1, CG 7838, bub1, BUB1, Dmbub1, DmBUB1, l(2)k06109, dBUB1, 31/13, l(2)k03113, BcDNA:LD23835, Bub1, bubR1, BUBR1, mcl(2)Z1525, DmBubRI" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013212:Mad3/Bub1 homology region 1, IPR015661:Mitotic spindle checkpoint protein Bub1/Mad3, IPR017441:Protein kinase, ATP binding site, IPR011990:Tetratricopeptide-like helical domain" CG7838 11-Aug-17 DroID_v2017_08 "Drer\bub1bb, Drer\bub1, Drer\bub1ba" "Scer\BUB1, Scer\MAD3" "Cele\bub-1, Cele\san-1" "Xtro\bub1, Xtro\bub1b" "Mmus\Bub1, Mmus\Bub1b" "Hsap\BUB1B, Hsap\BUB1" FBgn0020378 Sp1 Sp1 http://flybase.org/reports/FBgn0020378 - protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with btd sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with btd imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001145452" nucleus ; GO:0005634 | inferred from sequence or structural similarity with btd nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 "SP1, D-Sp1, D.Sp1, CG1343, Sp1, dSp1, sp1, D-Sp8" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1343 11-Aug-17 DroID_v2017_08 "Drer\sp1, Drer\sp8b, Drer\sp8a, Drer\sp3b, Drer\sp5a, Drer\sp2, Drer\klf13, Drer\sp9, Drer\sp5b, Drer\sp4, Drer\zgc:77358, Drer\sp3a, Drer\sp5l, Drer\klf11b, Drer\zgc:153115, Drer\sp7" - "Cele\sptf-3, Cele\sptf-1" "Xtro\sp1, Xtro\sp5l, Xtro\sp7, Xtro\sp5, Xtro\sp4, Xtro\sp6, Xtro\sp3, Xtro\sp9, Xtro\sp2" "Mmus\Sp7, Mmus\Sp1, Mmus\Sp9, Mmus\Sp2, Mmus\Sp6, Mmus\Sp8, Mmus\Sp5, Mmus\Sp4, Mmus\Klf13" "Hsap\SP7, Hsap\SP8, Hsap\KLF13, Hsap\SP4, Hsap\SP9, Hsap\SP5, Hsap\SP3, Hsap\ZNF48, Hsap\SP1, Hsap\SP6, Hsap\SP2" " larval stage , larval stage | third instar , embryonic stage , oogenesis stage , embryonic stage | stage 13 , adult stage && oogenesis stage " " ventral thoracic disc

, eye-antennal disc | restricted

, ventral nerve cord | restricted

, embryonic peripheral nervous system

, larval brain | restricted

, nurse cell

, antennal disc

, oocyte

, proneural cluster

, chordotonal organ | lateral

, chordotonal organ precursor cell

, chordotonal organ precursor cell | lateral

" "homeotic,size defective,visible,viable" "wing,leg,ectopic,medial,distal,first segment of antenna,second segment of antenna,wing margin bristle" FBgn0040096 lectin-33A lectin-33A http://flybase.org/reports/FBgn0040096 protein_coding_gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - "AC007083a, AC 007083A, CG16834, lectin-33A, lecti-33A, lectin-33a" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG16834 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-241l7.2, Drer\si:ch211-125e6.14, Drer\selp, Drer\si:dkeyp-75b4.10, Drer\si:dkey-241l7.3, Drer\colec11, Drer\si:dkey-83f18.10, Drer\si:dkey-216e24.3, Drer\si:ch211-125e6.13, Drer\si:dkey-9i23.5, Drer\clec19a, Drer\si:dkey-9i23.4, Drer\si:dkey-241l7.5, Drer\zgc:172053, Drer\si:ch211-125e6.5, Drer\si:ch211-125e6.12, Drer\si:ch211-170d8.5, Drer\si:ch211-125e6.11, Drer\si:dkey-241l7.6" - "Cele\clec-149, Cele\clec-28, Cele\clec-38" Xtro\reg4 "Mmus\Mbl1, Mmus\Clec4b2, Mmus\Clec4b1, Mmus\Sell, Mmus\Clec4a3, Mmus\Cd209d, Mmus\Clec4a2, Mmus\Clec4d, Mmus\Clec4a1, Mmus\Clec4n, Mmus\Clec4a4" "Hsap\CLEC11A, Hsap\CLEC4C, Hsap\CLEC4A, Hsap\SFTPD" viable FBgn0039050 CG17110 - http://flybase.org/reports/FBgn0039050 protein_coding_gene aminoacylase activity ; GO:0004046 | inferred from electronic annotation with InterPro:IPR010159 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010159 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010159 CG17110 "IPR002933:Peptidase M20, IPR010159:N-acyl-L-amino-acid amidohydrolase, IPR011650:Peptidase M20, dimerisation domain" CG17110 11-Aug-17 DroID_v2017_08 "Drer\pm20d1.1, Drer\pm20d1.2, Drer\acy1, Drer\LOC100001620" Scer\CPS1 "Cele\C10C5.3, Cele\C06A6.4, Cele\C10C5.5, Cele\C44E12.1, Cele\C10C5.4" "Xtro\acy1.1, Xtro\pm20d1" "Mmus\Pm20d1, Mmus\Acy1" "Hsap\ABHD14A-ACY1, Hsap\ABHD14A, Hsap\PM20D1, Hsap\ACY1" FBgn0040502 CG8343 - http://flybase.org/reports/FBgn0040502 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - "GH10831, GH10831-Inc, BEST:GH10831, CG8343" "IPR001304:C-type lectin-like, IPR018378:C-type lectin, conserved site, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG8343 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-125e6.13, Drer\si:dkey-216e24.3, Drer\zgc:174904, Drer\LOC100331140, Drer\LOC101884413, Drer\LOC100007376, Drer\illr4, Drer\zgc:171670, Drer\LOC101886537, Drer\illr3, Drer\si:dkey-241l7.6, Drer\mrc1b, Drer\si:ch211-225k7.5, Drer\si:ch211-225k7.4, Drer\si:ch211-125e6.12, Drer\si:ch73-343l4.2, Drer\zgc:172053, Drer\si:ch73-361h17.1, Drer\si:ch211-125e6.11, Drer\si:ch211-232p21.6, Drer\si:dkey-61f9.2, Drer\clec19a, Drer\si:dkey-241l7.2, Drer\si:ch211-283g2.3, Drer\si:ch211-214k5.3, Drer\mrc2, Drer\selp, Drer\si:ch211-133n4.7, Drer\illr1, Drer\si:dkey-9i23.5, Drer\si:ch73-122g19.1, Drer\illr2, Drer\mrc1a, Drer\si:ch211-125e6.5, Drer\zmp:0000000937, Drer\si:dkey-241l7.3, Drer\si:dkey-241l7.5, Drer\LOC101884526, Drer\si:ch211-170d8.5, Drer\zmp:0000000924, Drer\si:dkey-187i8.2, Drer\si:dkey-61f9.1, Drer\colec10, Drer\cd209, Drer\si:ch73-86n18.1, Drer\si:dkeyp-75b4.10, Drer\si:ch73-343l4.8, Drer\si:dkey-9i23.4, Drer\si:ch73-111e15.1, Drer\colec11" - "Cele\clec-36, Cele\clec-184, Cele\clec-48, Cele\clec-45, Cele\clec-39, Cele\clec-185, Cele\clec-53, Cele\clec-51, Cele\clec-202, Cele\clec-5, Cele\clec-194, Cele\clec-160, Cele\clec-43, Cele\clec-149, Cele\clec-204, Cele\clec-17, Cele\clec-86, Cele\clec-7, Cele\clec-38, Cele\clec-49, Cele\clec-179, Cele\clec-161, Cele\clec-181, Cele\clec-199, Cele\clec-31, Cele\clec-89, Cele\clec-265, Cele\C25G4.17, Cele\Y38H6C.8, Cele\clec-198, Cele\clec-52" "Xtro\asgr1, Xtro\colec10, Xtro\clec4m, Xtro\colec11, Xtro\mrc2, Xtro\mrc1" "Mmus\Reg3g, Mmus\Cd209e, Mmus\Clec4e, Mmus\Cd209f, Mmus\Reg3a, Mmus\Mrc1, Mmus\Clec4f, Mmus\Reg4, Mmus\Asgr2, Mmus\Reg2, Mmus\Cd209g, Mmus\Colec11, Mmus\Cd209a, Mmus\Clec4d, Mmus\Clec4b1, Mmus\Cd209c, Mmus\Colec10, Mmus\Reg1, Mmus\Clec4a2, Mmus\Asgr1, Mmus\Reg3d, Mmus\Mrc2, Mmus\Clec4a1, Mmus\Cd207, Mmus\Clec4g, Mmus\Cd209d, Mmus\Mgl2, Mmus\Fcer2a, Mmus\Reg3b, Mmus\Clec4b2, Mmus\Clec10a, Mmus\Cd209b, Mmus\Clec4n, Mmus\Clec4a3, Mmus\Clec4a4, Mmus\Sftpd" "Hsap\CLEC4G, Hsap\REG3A, Hsap\COLEC11, Hsap\FCER2, Hsap\CD209, Hsap\CLEC4D, Hsap\CLEC4M, Hsap\REG3G, Hsap\CLEC4F, Hsap\CLEC4E, Hsap\KLRF1, Hsap\MRC1, Hsap\CLEC4A, Hsap\MBL2, Hsap\CLEC10A, Hsap\CLEC4C, Hsap\REG4, Hsap\REG1B, Hsap\ASGR2, Hsap\REG1A, Hsap\CD207, Hsap\COLEC10, Hsap\ASGR1, Hsap\CLEC6A, Hsap\SFTPD, Hsap\CLEC17A" viable FBgn0004003 wbl windbeutel http://flybase.org/reports/FBgn0004003 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q86BJ3 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:O44342 "protein secretion ; GO:0009306 | inferred from electronic annotation with InterPro:IPR012883 dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype protein targeting to Golgi ; GO:0000042 | traceable author statement embryo development ending in birth or egg hatching ; GO:0009792 | traceable author statement regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | non-traceable author statement protein targeting to Golgi ; GO:0000042 | inferred from genetic interaction with pip protein processing ; GO:0016485 | inferred from genetic interaction with ea protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000259063 maternal specification of dorsal/ventral axis, oocyte, soma encoded ; GO:0007313 | traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement" endoplasmic reticulum lumen ; GO:0005788 | inferred from electronic annotation with InterPro:IPR012883 endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | traceable author statement "wind, Windb, wbt, Wind, CG7225, wbl, Wbl" "IPR011679:Endoplasmic reticulum resident protein 29, C-terminal, IPR012336:Thioredoxin-like fold, IPR012883:ERp29, N-terminal, IPR016855:Endoplasmic reticulum resident protein 29" CG7225 11-Aug-17 DroID_v2017_08 - - - Xtro\erp29 Mmus\Erp29 Hsap\ERP29 " adult stage | male , embryonic stage | early , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S8-10 " " ovary

, follicle cell

" "wild-type,lethal,non-rescuable maternal effect,recessive,partially,small body,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable,visible" "embryo,embryonic/first instar larval cuticle,maternal effect,embryonic epidermis,ventral,somatic clone,trichogen cell" FBgn0053807 His1:CG33807 His1:CG33807 http://flybase.org/reports/FBgn0053807 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33807, His1:CG33807" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33807 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-36p18.1, Drer\si:ch1073-159d7.7, Drer\h1fx, Drer\zgc:163061, Drer\zgc:153405, Drer\h1m, Drer\zgc:110216, Drer\zgc:110425, Drer\h1f0, Drer\si:dkey-261m9.12, Drer\si:ch211-113a14.24, Drer\si:dkey-108k21.21, Drer\si:dkey-108k21.14, Drer\histh1l, Drer\si:dkey-108k21.10" Scer\HHO1 "Cele\his-24, Cele\hil-5, Cele\hil-4, Cele\hil-2, Cele\hil-6, Cele\hil-3" Xtro\h1f0 "Mmus\H1fnt, Mmus\Hist1h1d, Mmus\H1fx, Mmus\Hist1h1t, Mmus\Hist1h1b, Mmus\H1foo, Mmus\Hist1h1c, Mmus\Hist1h1a, Mmus\Hils1, Mmus\Hist1h1e" "Hsap\H1FOO, Hsap\HIST1H1A, Hsap\HIST1H1D, Hsap\HIST1H1C, Hsap\HIST1H1B, Hsap\HIST1H1T, Hsap\H1FX, Hsap\H1F0, Hsap\H1FNT, Hsap\HIST1H1E" FBgn0038755 Hs6st Heparan sulfate 6-O-sulfotransferase http://flybase.org/reports/FBgn0038755 protein_coding_gene heparan sulfate 6-O-sulfotransferase activity ; GO:0017095 | inferred from biological aspect of ancestor with PANTHER:PTN000301790 "imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement primary branching, open tracheal system ; GO:0007428 | traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype inferred from genetic interaction with Hs2st heparan sulfate proteoglycan biosynthetic process, enzymatic modification ; GO:0015015 | inferred from biological aspect of ancestor with PANTHER:PTN000301790 regulation of canonical Wnt signaling pathway ; GO:0060828 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype regulation of decapentaplegic signaling pathway ; GO:0090097 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | traceable author statement regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR010635" "Hs6st, dHS6ST, DmHs6st, CG17188, CG18533, CG11683, CG4451, hs6st" "IPR010635:Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR005331:Sulfotransferase" CG4451 11-Aug-17 DroID_v2017_08 "Drer\hs6st3a, Drer\hs6st3b, Drer\hs6st1b, Drer\hs6st2, Drer\hs6st1a" - Cele\hst-6 "Xtro\hs6st1, Xtro\hs6st3" "Mmus\Hs6st2, Mmus\Hs6st1, Mmus\Hs6st3" "Hsap\HS6ST1, Hsap\HS6ST2, Hsap\HS6ST3" "viable,fertile,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,increased mortality during development,partially lethal - majority die,size defective" "eye,embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,embryonic/larval dorsal branch,embryonic/larval trachea,imaginal tracheoblast,presumptive embryonic/larval tracheal system,wing margin,wing disc,wing margin bristle" DRSC15581 I -2.899816299 0.237184502 0.369657153 -0.169190384 -0.051526583 -0.931438798 FBgn0001087 g garnet http://flybase.org/reports/FBgn0001087 "FBgn0001800, FBgn0030516, FBgn0030517" protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with AP-2α intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002553 lysosome organization ; GO:0007040 | inferred from sequence or structural similarity ocellus pigment biosynthetic process ; GO:0008055 | inferred from direct assay endocytosis ; GO:0006897 | inferred from mutant phenotype eye pigment biosynthetic process ; GO:0006726 | inferred from expression pattern exocytosis ; GO:0006887 | inferred from mutant phenotype Golgi to endosome transport ; GO:0006895 | non-traceable author statement eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype lysosomal transport ; GO:0007041 | traceable author statement eye pigment biosynthetic process ; GO:0006726 | inferred from direct assay negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | inferred from genetic interaction with p eye pigment biosynthetic process ; GO:0006726 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype intracellular transport ; GO:0046907 | traceable author statement determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype AP-3 adaptor complex ; GO:0030123 | inferred from electronic annotation with InterPro:IPR010474 endoplasmic reticulum ; GO:0005783 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay Golgi-associated vesicle ; GO:0005798 | non-traceable author statement Golgi stack ; GO:0005795 | inferred from direct assay AP-3 adaptor complex ; GO:0030123 | non-traceable author statement "g, cg11197, CG11197, delta, CG10986, l(1)Mc19, AP3delta, apl5, AP-3delta, garnet" "IPR010474:AP-3 complex subunit delta-1, IPR002553:Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR017105:Adaptor protein complex AP-3, delta subunit" CG10986 11-Aug-17 DroID_v2017_08 Drer\ap3d1 Scer\APL5 Cele\apd-3 Xtro\ap3d1 Mmus\Ap3d1 Hsap\AP3D1 adult stage "eye color defective,recessive,courtship behavior defective,male,short lived,behavior defective,visible,body color defective,viable,reduced,fertile,wild-type,cell autonomous,lethal - all die before end of embryonic stage,some die during embryonic stage,female,lethal,female fertile,male sterile" "pigment cell,testis sheath,Malpighian tubule,pigment granule,eye" DRSC20335 E 0.076386202 -0.437177995 2.861276213 0.824893468 -0.880786372 0.061513672 FBgn0036499 CG7276 - http://flybase.org/reports/FBgn0036499 protein_coding_gene dynein intermediate chain binding ; GO:0045505 | inferred from sequence or structural similarity with Dlc90F microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with Dlc90F dynein complex ; GO:0030286 | inferred from sequence or structural similarity with Dlc90F CG7276 IPR005334:Tctex-1 CG7276 11-Aug-17 DroID_v2017_08 "Drer\tctex1d1, Drer\dynlt3, Drer\tctex1d2" - Cele\dylt-2 Xtro\tctex1d1 "Mmus\Tcte3, Mmus\Dynlt3, Mmus\Gm3448, Mmus\Tctex1d2, Mmus\Tctex1d4, Mmus\Gm3417, Mmus\Tctex1d1" "Hsap\TCTE3, Hsap\TCTEX1D1, Hsap\TCTEX1D4, Hsap\TCTEX1D2, Hsap\DYNLT3" DRSC10797 K 0.395446703 -0.135752778 -0.140763961 -0.256543654 2.182186326 -0.551875906 FBgn0027081 ThrRS Threonyl-tRNA synthetase http://flybase.org/reports/FBgn0027081 "FBgn0022209, FBgn0032411" protein_coding_gene "threonine-tRNA ligase activity ; GO:0004829 | inferred from electronic annotation with InterPro:IPR002320 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002314, InterPro:IPR002320, InterPro:IPR012947 threonine-tRNA ligase activity ; GO:0004829 | inferred from sequence or structural similarity threonine-tRNA ligase activity ; GO:0004829 | traceable author statement" threonyl-tRNA aminoacylation ; GO:0006435 | inferred from electronic annotation with InterPro:IPR002320 threonyl-tRNA aminoacylation ; GO:0006435 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002320 mitochondrion ; GO:0005739 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement "CG5353, l(2)k04203, P539, threonyl-tRNA synthetase, ThrRS, TRS, 42/3, Aats-thr" "IPR002314:Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), IPR002320:Threonine-tRNA ligase, class IIa, IPR004095:TGS, IPR004154:Anticodon-binding, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR012675:Beta-grasp domain, IPR012676:TGS-like, IPR012947:Threonyl/alanyl tRNA synthetase, SAD, IPR018163:Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR033728:Threonine-tRNA ligase catalytic core domain" CG5353 11-Aug-17 DroID_v2017_08 "Drer\tars, Drer\tars2, Drer\cenpq, Drer\tarsl2, Drer\rprd2b" "Scer\THS1, Scer\MST1" Cele\tars-1 "Xtro\mrpl39, Xtro\tars, Xtro\tarsl2" "Mmus\Tars, Mmus\Tarsl2, Mmus\Mrpl39, Mmus\Tars2" "Hsap\TARS, Hsap\MRPL39, Hsap\TARSL2, Hsap\TARS2" embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "lethal,recessive,neuroanatomy defective" "lysosome & larval fat body | somatic clone | cell autonomous,ganglion mother cell" FBgn0039291 CG13663 - http://flybase.org/reports/FBgn0039291 protein_coding_gene - - - CG13663 IPR019387:Uncharacterised domain SAYSvFN CG13663 11-Aug-17 DroID_v2017_08 Drer\si:ch211-59d15.9 - Cele\C13F10.5 - Mmus\Saysd1 Hsap\SAYSD1 viable FBgn0259982 l(2)35Cc lethal (2) 35Cc http://flybase.org/reports/FBgn0259982 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR011599 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from biological aspect of ancestor with PANTHER:PTN000331216 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR011599 prefoldin complex ; GO:0016272 | inferred from electronic annotation with InterPro:IPR011599 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000331216 "CG15266, l(2)35Cc, l(2)br50, l35Cc, br50, BG:DS07295.5" "IPR004127:Prefoldin alpha-like, IPR011599:Prefoldin alpha subunit, archaea-type" CG15266 11-Aug-17 DroID_v2017_08 Drer\uxt - Cele\F35H10.6 - Mmus\Uxt Hsap\UXT lethal FBgn0261278 grp grapes http://flybase.org/reports/FBgn0261278 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay protein kinase activity ; GO:0004672 | non-traceable author statement" mitotic DNA replication checkpoint ; GO:0033314 | inferred from mutant phenotype cellularization ; GO:0007349 | traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype response to radiation ; GO:0009314 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from mutant phenotype signal transduction involved in mitotic DNA damage checkpoint ; GO:1902402 | inferred from biological aspect of ancestor with PANTHER:PTN002389494 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | inferred from mutant phenotype cell cycle checkpoint ; GO:0000075 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype inferred from genetic interaction with nbs cell cycle arrest ; GO:0007050 | inferred from mutant phenotype regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | traceable author statement spindle assembly ; GO:0051225 | inferred from mutant phenotype centrosome separation ; GO:0051299 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | traceable author statement mitotic cell cycle checkpoint ; GO:0007093 | traceable author statement peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "grp, chk1, CG17161, Grp, CHK1/Grapes, Chk1, CHK1, dChk1, lemp, 1C, Pk?1, Pk36A, DmChk1, grps, Grp/DChk1, l(2)k15102, grp(chk), Dchk1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR034670:Checkpoint kinase 1, catalytic domain" CG17161 11-Aug-17 DroID_v2017_08 Drer\chek1 "Scer\RTK1, Scer\CHK1, Scer\PRR2, Scer\SAT4, Scer\HRK1, Scer\NPR1, Scer\KKQ8, Scer\HAL5" "Cele\R02C2.1, Cele\kin-34, Cele\R02C2.6, Cele\kin-33, Cele\Y43D4A.6, Cele\chk-1" Xtro\chek1 Mmus\Chek1 Hsap\CHEK1 " embryonic stage -- adult stage , adult stage && oogenesis stage , embryonic stage " oocyte

FBgn0023171 rnh1 ribonuclease H1 http://flybase.org/reports/FBgn0023171 "FBgn0020291, FBgn0022077, FBgn0024594" protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR017067 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002156, InterPro:IPR012337 RNA-DNA hybrid ribonuclease activity ; GO:0004523 | inferred from sequence or structural similarity RNA-DNA hybrid ribonuclease activity ; GO:0004523 | inferred from direct assay" "DNA replication, removal of RNA primer ; GO:0043137 | inferred from biological aspect of ancestor with PANTHER:PTN000068227" - "RNase H1, rnhl, 74/9, l(2)43F1-5, l(2)k07624, l(2)k07409, l(2)43Fa, RnH1, CG8729, rnh1" "IPR011320:Ribonuclease H1, N-terminal, IPR002156:Ribonuclease H domain, IPR009027:Ribosomal protein L9/RNase H1, N-terminal, IPR012337:Ribonuclease H-like domain, IPR017067:Ribonuclease H1, eukaryote" CG8729 11-Aug-17 DroID_v2017_08 Drer\rnaseh1 Scer\RNH1 "Cele\rnh-1.1, Cele\K12D12.5, Cele\rnh-1.0, Cele\rnh-1.3" "Xtro\rnaseh1, Xtro\MGC146443, Xtro\LOC100493932" Mmus\Rnaseh1 Hsap\RNASEH1 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of prepupal stage,some die during prepupal stage,developmental rate defective,melanotic mass phenotype,viable" "stage P4(ii) prepupa,imaginal disc,embryonic/larval central nervous system,melanotic mass" FBgn0032358 Ppt2 Palmitoyl-protein Thioesterase 2 http://flybase.org/reports/FBgn0032358 protein_coding_gene palmitoyl hydrolase activity ; GO:0098599 | inferred from genetic interaction with Ppt1 palmitoyl-(protein) hydrolase activity ; GO:0008474 | inferred from sequence or structural similarity with UniProtKB:O35448 macromolecule depalmitoylation ; GO:0098734 | inferred from genetic interaction with Ppt1 lysosome ; GO:0005764 | inferred from direct assay "PPT-2, Ppt2, CG4851" "IPR002472:Palmitoyl protein thioesterase, IPR030295:Lysosomal thioesterase PPT2, IPR029058:Alpha/Beta hydrolase fold" CG4851 11-Aug-17 DroID_v2017_08 "Drer\zgc:55413, Drer\zgc:77118, Drer\ppt1, Drer\zgc:55621, Drer\ppt2, Drer\zgc:66024, Drer\zgc:113969" - - "Xtro\ppt1, Xtro\ppt2" "Mmus\Ppt1, Mmus\Ppt2" "Hsap\PPT2, Hsap\EGFL8, Hsap\PPT1" "viable,fertile" FBgn0036291 CG10681 - http://flybase.org/reports/FBgn0036291 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10681 IPR019371:Uncharacterised domain KxDL CG10681 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-202a12.4, Drer\kxd1, Drer\uba52, Drer\ubc, Drer\ubb, Drer\nedd8, Drer\nedd8l" - "Cele\F52C6.3, Cele\F52C6.2, Cele\ned-8, Cele\kxd-1, Cele\ubq-2" "Xtro\kxd1, Xtro\nedd8, Xtro\uba52, Xtro\ubc, Xtro\rps27a" "Mmus\Kxd1, Mmus\Ubd, Mmus\Rps27a, Mmus\Isg15, Mmus\Ubb, Mmus\Ubc, Mmus\Nedd8, Mmus\Uba52" "Hsap\UBD, Hsap\ISG15, Hsap\UBA52, Hsap\KXD1, Hsap\RPS27A, Hsap\NEDD8, Hsap\UBB, Hsap\UBC" viable FBgn0040232 cmet CENP-meta http://flybase.org/reports/FBgn0040232 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 kinetochore binding ; GO:0043515 | inferred from electronic annotation with InterPro:IPR033066 ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from sequence or structural similarity with HGNC:1856 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity" attachment of mitotic spindle microtubules to kinetochore ; GO:0051315 | inferred from electronic annotation with InterPro:IPR033066 regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 neurogenesis ; GO:0022008 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 condensed chromosome outer kinetochore ; GO:0000940 | non-traceable author statement kinesin complex ; GO:0005871 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay "CENP-meta, DmCmeta, CENP-E meta, CG6392, l(2)04431, cmet, Cenp-E, CENP-E, CENPmeta, Cenp-meta, Cenp-M, CENP-Meta, CENP-META, Cenp_E, CENPE, Cmet, KIF 10, DmCmet, KIF10" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR033066:Centromere-associated protein E" CG6392 11-Aug-17 DroID_v2017_08 "Drer\znf185, Drer\kif1b, Drer\kif22, Drer\cenpe, Drer\kif13a, Drer\kif1aa, Drer\golgb1, Drer\kif19, Drer\golga4, Drer\si:dkey-26i13.8, Drer\kif18a, Drer\kif1ab, Drer\kif13bb" "Scer\MLP1, Scer\KIP2, Scer\MLP2, Scer\KIP3, Scer\USO1" "Cele\anc-1, Cele\klp-4, Cele\F59A2.2, Cele\unc-104, Cele\che-10, Cele\golg-4" "Xtro\kif22, Xtro\kif19, Xtro\kif18b, Xtro\cenpe, Xtro\kif18a" "Mmus\Morc3, Mmus\Kif13a, Mmus\Kif18a, Mmus\Golgb1, Mmus\Kif19a, Mmus\Kif1b, Mmus\Kif13b, Mmus\Golga4, Mmus\Kif18b, Mmus\Cenpe, Mmus\Kif1a, Mmus\Cenpf, Mmus\Kif22" "Hsap\KIF22, Hsap\MORC3, Hsap\GOLGB1, Hsap\KIF18B, Hsap\KIF13A, Hsap\GOLGA4, Hsap\KIF19, Hsap\CENPF, Hsap\KIF18A, Hsap\KIF1B, Hsap\KIF13B, Hsap\CENPE" "visible,conditional,heat sensitive,size defective,viable,fertile,lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,neuroanatomy defective" "eye,conditional,heat sensitive,embryonic/first instar larval cuticle,maternal effect,mitosis & nuclear chromosome,mitotic cell cycle,mitosis & nuclear chromosome | germ-line clone,mitotic anaphase | germline clone,centrosome | germline clone,mitotic metaphase | germline clone,condensed nuclear chromosome,spermatocyte,spindle microtubule,astral microtubule,spindle pole,ganglion mother cell,trichogen cell" DRSC03511 K 1.207261744 0.867315309 0.344867858 0.045488113 1.987819973 0.280797421 FBgn0265042 Irk1 Inwardly rectifying potassium channel 1 http://flybase.org/reports/FBgn0265042 protein_coding_gene inward rectifier potassium channel activity ; GO:0005242 | inferred from direct assay inward rectifier potassium channel activity ; GO:0005242 | inferred from biological aspect of ancestor with PANTHER:PTN000205946 potassium ion import ; GO:0010107 | inferred from biological aspect of ancestor with PANTHER:PTN000205946 locomotor rhythm ; GO:0045475 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from direct assay wing disc development ; GO:0035220 | inferred from mutant phenotype regulation of membrane potential ; GO:0042391 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000205946 "Irk1, CG44159, CG13836, Dir, dKirI, DIR, irk1, CG6747, ir, Ir, Dm_3R:100326, Dm_3R:100349" "IPR014756:Immunoglobulin E-set, IPR013518:Potassium channel, inwardly rectifying, Kir, cytoplasmic, IPR016449:Potassium channel, inwardly rectifying, Kir" CG44159 11-Aug-17 DroID_v2017_08 "Drer\kcnj9, Drer\kcnj1b, Drer\LOC103910156, Drer\kcnj5, Drer\kcnj2a, Drer\kcnj16, Drer\kcnj1a.6, Drer\kcnj2b, Drer\LOC103909814, Drer\kcnj6, Drer\kcnj11l, Drer\kcnj3b, Drer\kcnj1a.3, Drer\kcnj3a, Drer\kcnj12b, Drer\kcnj1a.5, Drer\si:dkey-100n10.2, Drer\kcnj1a.4, Drer\kcnj12a, Drer\zgc:162160, Drer\si:dkey-106c17.3, Drer\kcnj8, Drer\kcnj15, Drer\kcnj14, Drer\kcnj13, Drer\si:ch211-113j13.2, Drer\kcnj10a, Drer\kcnj11, Drer\kcnj1a.2, Drer\kcnj1a.1" - "Cele\irk-1, Cele\irk-2, Cele\irk-3" "Xtro\kcnj4, Xtro\kcnj2, Xtro\kcnj3, Xtro\kcnj9, Xtro\kcnj13, Xtro\kcnj16, Xtro\kcnj14, Xtro\kcnj11, Xtro\kcnj10, Xtro\kcnj15, Xtro\kcnj12, Xtro\kcnj1" "Mmus\Kcnj5, Mmus\Kcnj12, Mmus\Kcnj11, Mmus\Kcnj3, Mmus\Kcnj9, Mmus\Kcnj8, Mmus\Kcnj4, Mmus\Kcnj6, Mmus\Kcnj2, Mmus\Kcnj15, Mmus\Kcnj13, Mmus\Kcnj14, Mmus\Kcnj10, Mmus\Kcnj1, Mmus\Kcnj16" "Hsap\KCNJ15, Hsap\KCNJ6, Hsap\KCNJ3, Hsap\KCNJ8, Hsap\KCNJ16, Hsap\KCNJ9, Hsap\KCNJ18, Hsap\KCNJ13, Hsap\KCNJ5, Hsap\KCNJ11, Hsap\KCNJ10, Hsap\KCNJ2, Hsap\KCNJ12, Hsap\KCNJ1, Hsap\KCNJ14, Hsap\KCNJ4" FBgn0040253 Ugt86Dg Ugt86Dg http://flybase.org/reports/FBgn0040253 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG17200, AC 006491G, Ugt86Dg, CG17200-PA" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG17200 11-Aug-17 DroID_v2017_08 "Drer\ugt5b1, Drer\ugt8, Drer\ugt1b5, Drer\ugt5b4, Drer\ugt5c3, Drer\ugt5c1, Drer\ugt1b2, Drer\ugt2a6, Drer\ugt2b1, Drer\ugt1b7, Drer\ugt5g1, Drer\ugt1b3, Drer\ugt2a2, Drer\ugt5a4, Drer\ugt2b6, Drer\ugt5a1, Drer\ugt5d1, Drer\zgc:172315, Drer\ugt5b3, Drer\ugt5b2, Drer\ugt5g2, Drer\ugt5a2, Drer\ugt5b6, Drer\ugt1b4, Drer\ugt5a5, Drer\ugt2a3, Drer\ugt5f1, Drer\ugt2b3, Drer\ugt2a5, Drer\ugt1ab, Drer\ugt2a1, Drer\ugt2a4, Drer\ugt1a1, Drer\ugt2b5, Drer\ugt5c2, Drer\ugt5e1" Scer\ATG26 "Cele\ugt-16, Cele\ugt-1, Cele\ugt-48, Cele\ugt-41, Cele\ugt-58, Cele\ugt-56, Cele\ugt-65, Cele\ugt-14, Cele\C03A7.13, Cele\ugt-10, Cele\F10D2.8, Cele\ugt-61, Cele\ugt-38, Cele\ugt-13, Cele\ugt-59, Cele\ugt-36, Cele\ugt-17, Cele\ugt-25, Cele\C23G10.6, Cele\ugt-21, Cele\ugt-51, Cele\ugt-60, Cele\ugt-2, Cele\ugt-24, Cele\H23N18.4, Cele\ugt-49, Cele\ugt-62, Cele\ugt-45, Cele\ugt-27, Cele\ugt-57, Cele\ugt-6, Cele\ugt-50, Cele\K04A8.10, Cele\F54C1.1, Cele\ugt-11, Cele\ugt-23, Cele\ugt-30, Cele\ugt-18, Cele\ugt-29, Cele\ugt-8, Cele\ugt-34, Cele\ugt-39, Cele\ugt-55, Cele\ugt-32, Cele\ugt-9, Cele\ugt-53, Cele\ugt-4, Cele\C03A7.12, Cele\ugt-47, Cele\ugt-44, Cele\ugt-33, Cele\ugt-7, Cele\Y43D4A.2, Cele\ugt-40, Cele\ugt-54, Cele\ugt-43, Cele\ugt-22, Cele\ugt-28, Cele\ugt-26, Cele\ugt-3, Cele\ugt-19, Cele\ugt-5, Cele\ugt-37, Cele\ugt-52, Cele\ugt-15, Cele\C55H1.1, Cele\ugt-35, Cele\ugt-12, Cele\ugt-46, Cele\ugt-20, Cele\ugt-31, Cele\ugt-42" "Xtro\ugt1a6, Xtro\ugt2a1, Xtro\ugt8, Xtro\ugt2b4, Xtro\ugt3a2" "Mmus\Ugt3a2, Mmus\Ugt1a1, Mmus\Ugt3a1, Mmus\Ugt1a6b, Mmus\Ugt1a10, Mmus\Ugt2b5, Mmus\Ugt8a, Mmus\Ugt2b38, Mmus\Ugt2a1, Mmus\Ugt2b35, Mmus\Ugt2a3, Mmus\Ugt1a5, Mmus\Ugt1a7c, Mmus\Ugt2b36, Mmus\Ugt1a9, Mmus\Ugt1a2, Mmus\Ugt2b1, Mmus\Ugt2a2, Mmus\Ugt2b37, Mmus\Ugt2b34" "Hsap\UGT2B7, Hsap\UGT3A1, Hsap\UGT1A6, Hsap\UGT1A8, Hsap\UGT2B4, Hsap\UGT1A4, Hsap\UGT2A2, Hsap\UGT2B10, Hsap\UGT1A5, Hsap\UGT2B15, Hsap\UGT1A9, Hsap\UGT2B17, Hsap\UGT1A10, Hsap\UGT1A1, Hsap\UGT2B28, Hsap\UGT3A2, Hsap\UGT1A3, Hsap\UGT2A3, Hsap\UGT2A1, Hsap\UGT2B11, Hsap\UGT1A7, Hsap\UGT8" viable FBgn0015321 Ubc4 Ubiquitin conjugating enzyme 4 http://flybase.org/reports/FBgn0015321 - protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with CG3356 proteasome binding ; GO:0070628 | inferred from physical interaction with Rpn10 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:4914 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000629609 regulation of cell cycle ; GO:0051726 | inferred from direct assay proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000629609 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:4914 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000629609 "E2, CG8284, UbcD4, Ubc4, UbcD4 E2" "IPR015940:Ubiquitin-associated domain, IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR009060:UBA-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG8284 11-Aug-17 DroID_v2017_08 "Drer\ube2kb, Drer\ube2ka" "Scer\UBC1, Scer\PEX4" "Cele\ubc-19, Cele\ubc-22, Cele\C28G1.10, Cele\ubc-20, Cele\uev-3, Cele\ubc-21" Xtro\ube2k Mmus\Ube2k Hsap\UBE2K viable FBgn0051613 His3:CG31613 His3:CG31613 http://flybase.org/reports/FBgn0051613 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG31613, His3:CG31613, His3" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG31613 11-Aug-17 DroID_v2017_08 "Drer\zgc:113983, Drer\h3f3b.1, Drer\h3f3d, Drer\h3f3c, Drer\cenpa, Drer\LOC108190747, Drer\zgc:173552, Drer\hist2h3ca1, Drer\zgc:113984, Drer\si:ch73-36p18.2, Drer\LOC108190746, Drer\h3f3a, Drer\hist2h3c, Drer\si:ch1073-429i10.3" "Scer\CSE4, Scer\HHT1, Scer\HHT2" "Cele\his-6, Cele\his-49, Cele\his-45, Cele\his-72, Cele\his-32, Cele\his-74, Cele\his-63, Cele\his-42, Cele\his-2, Cele\his-59, Cele\his-13, Cele\his-9, Cele\his-69, Cele\his-25, Cele\his-27, Cele\his-55, Cele\his-17, Cele\his-71" "Xtro\hist2h3d, Xtro\LOC100493036, Xtro\cenpa, Xtro\h3f3b" "Mmus\Hist1h3c, Mmus\H3f3a, Mmus\H3f3b, Mmus\Cenpa, Mmus\Hist2h3b, Mmus\Hist2h3c2, Mmus\Hist1h3i, Mmus\Hist1h3a, Mmus\Hist1h3g, Mmus\Hist1h3f, Mmus\Hist1h3e, Mmus\Hist2h3c1, Mmus\Hist1h3d, Mmus\Hist1h3h, Mmus\Hist1h3b" "Hsap\HIST1H3E, Hsap\HIST1H3B, Hsap\H3F3A, Hsap\HIST2H3C, Hsap\HIST2H3A, Hsap\H3F3C, Hsap\HIST2H3D, Hsap\HIST1H3F, Hsap\HIST1H3G, Hsap\HIST1H3D, Hsap\HIST1H3A, Hsap\HIST1H3I, Hsap\HIST3H3, Hsap\HIST1H3C, Hsap\H3F3B, Hsap\HIST1H3J, Hsap\HIST1H3H, Hsap\CENPA" DRSC21267 IE -4.167786228 -3.384989702 -7.378306454 -6.017557947 -0.325687388 -1.108666666 FBgn0036659 CG9701 - http://flybase.org/reports/FBgn0036659 protein_coding_gene beta-glucosidase activity ; GO:0008422 | inferred from biological aspect of ancestor with PANTHER:PTN000039458 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001360, InterPro:IPR013781, InterPro:IPR018120 glycosyl compound metabolic process ; GO:1901657 | inferred from biological aspect of ancestor with PANTHER:PTN000039458" - "CG9701, Dmel_CG9701" "IPR001360:Glycoside hydrolase family 1, IPR018120:Glycoside hydrolase family 1, active site, IPR017853:Glycoside hydrolase superfamily, IPR033132:Glycosyl hydrolases family 1, N-terminal conserved site" CG9701 11-Aug-17 DroID_v2017_08 "Drer\lctlb, Drer\lctla, Drer\kl, Drer\gba3, Drer\lct, Drer\klb" - "Cele\klo-1, Cele\klo-2" "Xtro\lctl, Xtro\gba3, Xtro\lct.2, Xtro\kl, Xtro\klb" "Mmus\Klb, Mmus\Lctl, Mmus\Lct, Mmus\Kl" "Hsap\KLB, Hsap\LCT, Hsap\GBA3, Hsap\LCTL, Hsap\KL" viable FBgn0027794 Lrpprc2 Leucine-rich pentatricopeptide repeat containing 2 http://flybase.org/reports/FBgn0027794 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with SLIRP2 regulation of transcription from mitochondrial promoter ; GO:1903108 | inferred from mutant phenotype regulation of rhodopsin mediated signaling pathway ; GO:0022400 | inferred from mutant phenotype regulation of mitochondrial mRNA stability ; GO:0044528 | inferred from mutant phenotype regulation of mitochondrial translation ; GO:0070129 | inferred from mutant phenotype regulation of oxidative phosphorylation ; GO:0002082 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay exon-exon junction complex ; GO:0035145 | colocalizes_with inferred from direct assay "EG:BACN32G11.3, CG14786, Lrpprc2, DmLrpprc2, ppr" "IPR002885:Pentatricopeptide repeat, IPR011990:Tetratricopeptide-like helical domain" CG14786 11-Aug-17 DroID_v2017_08 Drer\lrpprc - Cele\C04E6.11 Xtro\lrpprc Mmus\Lrpprc Hsap\LRPPRC viable FBgn0051792 CG31792 - http://flybase.org/reports/FBgn0051792 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN002384094 "CG17338, CG31792" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR003593:AAA+ ATPase domain" CG31792 11-Aug-17 DroID_v2017_08 "Drer\abcc3, Drer\abcc9, Drer\abcc6a, Drer\abcc2, Drer\abcc6b.2, Drer\abcc4, Drer\abcc5, Drer\cftr, Drer\abcc8, Drer\abcc12, Drer\abcc13, Drer\abcc10, Drer\abcc1, Drer\LOC100329706" "Scer\YCF1, Scer\YKR104W, Scer\BPT1, Scer\NFT1, Scer\YOR1, Scer\YBT1, Scer\VMR1" "Cele\mrp-3, Cele\mrp-1, Cele\mrp-2, Cele\mrp-6, Cele\mrp-7, Cele\mrp-5, Cele\mrp-8, Cele\mrp-4" "Xtro\abcc3, Xtro\abcc1, Xtro\abcc10, Xtro\cftr, Xtro\abcc4, Xtro\abcc6" "Mmus\Abcc2, Mmus\Abcc12, Mmus\Abcc1, Mmus\Cftr, Mmus\Abcc9, Mmus\Abcc3, Mmus\Abcc6, Mmus\Abcc8, Mmus\Abcc5, Mmus\Abcc10, Mmus\Abcc4" "Hsap\ABCC12, Hsap\ABCC9, Hsap\ABCC3, Hsap\ABCC10, Hsap\ABCC11, Hsap\ABCC4, Hsap\ABCC2, Hsap\ABCC1, Hsap\ABCC8, Hsap\CFTR, Hsap\ABCC6, Hsap\ABCC5" "viable,lethal" FBgn0035934 TrpA1 Transient receptor potential cation channel A1 http://flybase.org/reports/FBgn0035934 protein_coding_gene temperature-gated cation channel activity ; GO:0097604 | inferred from direct assay ligand-gated ion channel activity ; GO:0015276 | inferred from direct assay calcium channel activity ; GO:0005262 | inferred from direct assay cation channel activity ; GO:0005261 | inferred from direct assay bitter taste receptor activity ; GO:0033038 | NOT inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 neuronal signal transduction ; GO:0023041 | inferred from mutant phenotype mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from direct assay detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype cellular response to heat ; GO:0034605 | inferred from direct assay detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from direct assay detection of temperature stimulus involved in thermoception ; GO:0050960 | inferred from direct assay calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity detection of chemical stimulus involved in sensory perception of pain ; GO:0050968 | inferred from mutant phenotype positive regulation of calcium-mediated signaling ; GO:0050850 | inferred from mutant phenotype thermosensory behavior ; GO:0040040 | inferred from mutant phenotype detection of temperature stimulus involved in thermoception ; GO:0050960 | inferred from mutant phenotype thermotaxis ; GO:0043052 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of bitter taste ; GO:0001580 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from direct assay response to heat ; GO:0009408 | inferred from direct assay cation transport ; GO:0006812 | inferred from direct assay temperature compensation of the circadian clock ; GO:0010378 | inferred from mutant phenotype negative phototaxis ; GO:0046957 | inferred from mutant phenotype cation channel complex ; GO:0034703 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred by curator from GO:0005261 "dTrpA1, trpA1, DmTRPA1, dANKTM1, dTRPA1, TRPA1, ANKTM1, CT18073, CG5751, Anktm1, TrpA1, TRPA, CG5761, dtrpA1, Trp1A, TrpA, dTRPA, dTrpA, Trpa1, dmTRPA1, trpa1" "IPR005821:Ion transport domain, IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG5751 11-Aug-17 DroID_v2017_08 "Drer\otofa, Drer\myofl, Drer\bard1, Drer\myof, Drer\trpa1a, Drer\fer1l6, Drer\otofb, Drer\fer1l4, Drer\dysf, Drer\trpa1b" Scer\YAR1 "Cele\unc-44, Cele\trpa-1, Cele\mlt-4, Cele\T16G1.9" "Xtro\myof, Xtro\otof, Xtro\fer1l6, Xtro\trpa1" "Mmus\Sowahc, Mmus\Otof, Mmus\Bard1, Mmus\Sowahd, Mmus\Ank2, Mmus\Ank1, Mmus\Fer1l6, Mmus\Ank3, Mmus\Fer1l4, Mmus\Dysf, Mmus\Slf1, Mmus\Myof, Mmus\Trpa1" "Hsap\SOWAHD, Hsap\MYOF, Hsap\ANK3, Hsap\ANK2, Hsap\TRPA1, Hsap\ANK1, Hsap\SOWAHC, Hsap\OTOF, Hsap\BARD1, Hsap\DYSF, Hsap\FER1L6" "courtship behavior defective,male,heat sensitive,conditional,neuroanatomy defective,mating behavior defective,female limited,locomotor rhythm defective,taste perception defective,recessive,song defective,somatic clone,behavior defective,paralytic,neurophysiology defective,memory defective,circadian behavior defective,mating defective,learning defective,sleep defective,starvation stress response defective,tarsal response defective,locomotor behavior defective,smell perception defective,chemical sensitive,feeding behavior defective,male limited,pain response defective,proboscis extension reflex defective,progressive,chemosensitive behavior defective,thermotaxis behavior defective,female,visible,partially lethal - majority die,some die during pupal stage,lethal,phototaxis defective,heat stress response defective,temperature response defective" "dendrite | third instar larval stageGMR.PF,LNv neuron | third instar larval stage,neuromuscular junction | heat sensitive,indirect flight muscle motor neuron MN5,heat sensitive,dendrite | heat sensitivefutsch-C380,large labellar taste bristle,proboscis,adult olfactory receptor neuron ab11a,mesothoracic tergum,AC thermosensory neuron,intermediate labellar taste bristle" FBgn0015031 cype cyclope http://flybase.org/reports/FBgn0015031 "FBgn0010553, FBgn0031699, FBgn0040947, FBgn0063275" protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P09669 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProtKB:P09669" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P09669 lipid particle ; GO:0005811 | inferred from direct assay "CG14028, l(2)03771, cyc, Cyc, BcDNA:GH04604, CG18323, cype, COXVIc, VIc, Cype, COXH, COX6C, Cox6c" IPR004204:Cytochrome c oxidase subunit 6C CG14028 11-Aug-17 DroID_v2017_08 Drer\cox6c - "Cele\F29C4.2, Cele\Y111B2A.2, Cele\B0035.18" "Xtro\LOC100489195, Xtro\cox6c" Mmus\Cox6c Hsap\COX6C "lethal,recessive,partially lethal - majority die,visible,dominant,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,developmental rate defective,wild-type,maternal effect,semidominant,viable" "embryonic head,embryonic/first instar larval cuticle,denticle belt,ovary,germline clone,tergite,leg,wing,adult thorax,eye,ommatidium,macrochaeta,somatic clone,wing margin bristle,interommatidial bristle,supernumerary,amnioserosa,maternal effect,filzkorper,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,thorax,head,mesothoracic tergum,trichogen cell" FBgn0016131 Cdk4 Cyclin-dependent kinase 4 http://flybase.org/reports/FBgn0016131 "FBgn0004458, FBgn0010600, FBgn0010696, FBgn0022125" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 cyclin binding ; GO:0030332 | inferred from physical interaction with CycD protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity with HGNC:1773 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity" "cell growth ; GO:0016049 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 JAK-STAT cascade ; GO:0007259 | inferred from mutant phenotype inferred from genetic interaction with hop inferred from genetic interaction with upd1, CycD inferred from physical interaction with Stat92E cell proliferation ; GO:0008283 | inferred from genetic interaction with CycD positive regulation of cell proliferation ; GO:0008284 | inferred from biological aspect of ancestor with PANTHER:PTN000623979 response to organic substance ; GO:0010033 | inferred from biological aspect of ancestor with PANTHER:PTN000623979 regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000623979 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:1773 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | traceable author statement regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from biological aspect of ancestor with PANTHER:PTN000623979 open tracheal system development ; GO:0007424 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from biological aspect of ancestor with PANTHER:PTN000623979 regulation of cell growth ; GO:0001558 | traceable author statement" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000623979 cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000623979 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 "Cdk4/6, cdk4, CDK4, l(2)0671, l(2)sh0671, cdk4/6, CG5072, CDK4/6, l(2)s4639, l(2)k06503, l(2)05428, DmCdk4, 8-6, Pk?7, Pk53C, Cdk4, dCdk4, cdk" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG5072 11-Aug-17 DroID_v2017_08 "Drer\cdk4, Drer\cdk14, Drer\si:dkey-166c18.1, Drer\cdk21, Drer\cdk1, Drer\cdk15, Drer\cdk16, Drer\cdk5, Drer\LOC100536316, Drer\cdk17, Drer\cdk2, Drer\cdk6" "Scer\CDC28, Scer\PHO85, Scer\CAK1" "Cele\cdk-4, Cele\cdk-2" "Xtro\cdk18, Xtro\cdk17, Xtro\cdk5, Xtro\cdk6, Xtro\cdk2, Xtro\cdk14, Xtro\cdk4, Xtro\cdk1, Xtro\cdk15, Xtro\cdk16" "Mmus\Cdk4, Mmus\E030030I06Rik, Mmus\Cdk2, Mmus\Cdk15, Mmus\Cdk17, Mmus\Cdk5, Mmus\Cdk1, Mmus\Cdk16, Mmus\Cdk14, Mmus\Cdk6, Mmus\Cdk18" "Hsap\CDK5, Hsap\CDK2, Hsap\CDK18, Hsap\CDK17, Hsap\CDK16, Hsap\CDK3, Hsap\CDK4, Hsap\CDK15, Hsap\CDK1, Hsap\CDK14, Hsap\CDK6" embryonic stage -- adult stage "lethal,recessive,viable,fertile,maternal effect,poor,sterile,female,small body,decreased cell number,somatic clone,increased cell size,radiation sensitive,size defective,visible" "abdominal 5 ventral denticle belt,germline clone,maternal effect,embryonic/first instar larval cuticle,segment,head,adult,wing,abdominal 6 ventral denticle belt,rescuable maternal effect,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,abdominal 4 ventral denticle belt,embryonic head,tracheal branch primordium,dorsal trunk primordium,cell cycle,embryo,denticle belt,mesothoracic tergum" DRSC07358 IE -1.933465771 -2.656059343 -2.481610609 -3.220110809 1.177203104 0.1157009 FBgn0016791 csw::Src64B csw::Src64B http://flybase.org/reports/FBgn0016791 - engineered_fusion_gene - - - csw::Src64B - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "eye,cone cell,precursor,photoreceptor cell R7,ectopic,supernumerary,embryonic/larval tracheocyte,ectopic | embryonic stage,ectoderm,ventral,tracheal branch primordium,embryonic myoblast,cardioblast | embryonic stage,chorion,dorsal appendage,embryo,wing vein,mesoderm,terminal tracheal cell,embryonic/larval tracheal system" FBgn0001376 l(1)devl lethal decreased volume optic lobes http://flybase.org/reports/FBgn0001376 - gene - - - "l(1)2Bg, HM38, l(1)HM38, l(1)devl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" embryonic/larval brain FBgn0263397 Ih I[[h]] channel http://flybase.org/reports/FBgn0263397 protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR003938 regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype circadian sleep/wake cycle, sleep ; GO:0050802 | inferred from mutant phenotype optomotor response ; GO:0071632 | inferred from mutant phenotype cellular response to light intensity ; GO:0071484 | inferred from mutant phenotype proboscis extension reflex ; GO:0007637 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype regulation of dopamine secretion ; GO:0014059 | inferred from mutant phenotype regulation of glutamate secretion, neurotransmission ; GO:1903294 | inferred from genetic interaction with VGlut" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 "CG8585, Ih, I[[h]], DmIh, CR30068, BcDNA:GH25778, DMIH" "IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR003938:Potassium channel, voltage-dependent, EAG/ELK/ERG, IPR005821:Ion transport domain, IPR014710:RmlC-like jelly roll fold, IPR013621:Ion transport N-terminal" CG8585 11-Aug-17 DroID_v2017_08 "Drer\kcnh4b, Drer\hcn3, Drer\kcnh1b, Drer\LOC100535364, Drer\hcn4l, Drer\si:rp71-68n21.12, Drer\LOC101883600, Drer\kcnh8, Drer\LOC100334297, Drer\kcnh5a, Drer\kcnh1a, Drer\kcnh6a, Drer\hcn4, Drer\hcn2b, Drer\kcnh2a, Drer\kcnh6b, Drer\kcnh4a, Drer\kcnh5b, Drer\kcnh3, Drer\kcnh7" - - "Xtro\kcnh7, Xtro\kcnh6, Xtro\kcnh8, Xtro\hcn4, Xtro\hcn1, Xtro\kcnh1" "Mmus\Hcn1, Mmus\Hcn2, Mmus\Kcnh7, Mmus\Hcn3, Mmus\Kcnh8, Mmus\Kcnh3, Mmus\Kcnh1, Mmus\Kcnh4, Mmus\Kcnh2, Mmus\Hcn4, Mmus\Kcnh5, Mmus\Kcnh6" "Hsap\KCNH5, Hsap\KCNH3, Hsap\KCNH6, Hsap\HCN3, Hsap\HCN4, Hsap\KCNH8, Hsap\HCN2, Hsap\KCNH2, Hsap\KCNH7, Hsap\HCN1, Hsap\KCNH1, Hsap\KCNH4" FBgn0004516 Gad1 Glutamic acid decarboxylase 1 http://flybase.org/reports/FBgn0004516 "FBgn0001088, FBgn0001110, FBgn0016015" protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 glutamate decarboxylase activity ; GO:0004351 | inferred from sequence or structural similarity inferred from direct assay glutamate decarboxylase activity ; GO:0004351 | non-traceable author statement response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with kcc gamma-aminobutyric acid biosynthetic process ; GO:0009449 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype neurotransmitter receptor metabolic process ; GO:0045213 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype glutamate catabolic process ; GO:0006538 | inferred from mutant phenotype gamma-aminobutyric acid biosynthetic process ; GO:0009449 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay "Gad1, DGAD1, gad, GAD, dgad1, gad1, GAD1, Gad, dGad1, l(3)64An, DGad1, l(3)SH10, GAD[[1]], Glb, CG14994, GAD-1" "IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR021115:Pyridoxal-phosphate binding site, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG14994 11-Aug-17 DroID_v2017_08 "Drer\csad, Drer\gad2, Drer\gad1a, Drer\gad1b, Drer\zgc:163121" - Cele\unc-25 "Xtro\gad1.1, Xtro\csad, Xtro\gad2, Xtro\gad1.2, Xtro\gadl1" "Mmus\Gad1, Mmus\Gad2, Mmus\Gadl1, Mmus\Csad" "Hsap\GAD2, Hsap\CSAD, Hsap\GADL1, Hsap\GAD1" "neurophysiology defective,locomotor behavior defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,flight defective,viable,smell perception defective,behavior defective" "neuromuscular junction,bouton,mushroom body anterior paired lateral cell" FBgn0024814 Clc Clathrin light chain http://flybase.org/reports/FBgn0024814 - protein_coding_gene clathrin heavy chain binding ; GO:0032050 | inferred from biological aspect of ancestor with PANTHER:PTN000067451 structural molecule activity ; GO:0005198 | inferred from biological aspect of ancestor with PANTHER:PTN000067451 clathrin heavy chain binding ; GO:0032050 | inferred from sequence or structural similarity with HGNC:2092 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR000996 synaptic vesicle coating ; GO:0016183 | traceable author statement clathrin-dependent endocytosis ; GO:0072583 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | non-traceable author statement clathrin coat of trans-Golgi network vesicle ; GO:0030130 | inferred from electronic annotation with InterPro:IPR000996 clathrin-coated pit ; GO:0005905 | traceable author statement mitotic spindle ; GO:0072686 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay clathrin coat of coated pit ; GO:0030132 | inferred from direct assay synaptic vesicle ; GO:0008021 | traceable author statement clathrin vesicle coat ; GO:0030125 | traceable author statement clathrin complex ; GO:0071439 | inferred from sequence or structural similarity with HGNC:2092 plasma membrane ; GO:0005886 | inferred from direct assay clathrin-coated vesicle ; GO:0030136 | inferred from direct assay clathrin vesicle coat ; GO:0030125 | inferred from direct assay coated vesicle ; GO:0030135 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "CG6948, CLC, Clc, clc, clc1" IPR000996:Clathrin light chain CG6948 11-Aug-17 DroID_v2017_08 "Drer\clta, Drer\cltb" Scer\CLC1 Cele\clic-1 "Xtro\clta, Xtro\cltb" "Mmus\Clta, Mmus\Cltb" "Hsap\CLTB, Hsap\CLTA" viable FBgn0261823 Asx Additional sex combs http://flybase.org/reports/FBgn0261823 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR026905 chromatin binding ; GO:0003682 | inferred from direct assay deubiquitinase activator activity ; GO:0035800 | inferred from direct assay "monoubiquitinated histone H2A deubiquitination ; GO:0035522 | inferred from direct assay inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | non-traceable author statement regulation of ubiquitin-specific protease activity ; GO:2000152 | inferred from direct assay regulation of gene expression ; GO:0010468 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype antennal development ; GO:0007469 | inferred from mutant phenotype cell fate determination ; GO:0001709 | inferred from genetic interaction with Ubx sex comb development ; GO:0045498 | traceable author statement apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay PR-DUB complex ; GO:0035517 | inferred from direct assay inferred from physical interaction with calypso "Asx, CG8787, ASX, xen, FBgn0261823" "IPR024814:Polycomb protein ASX, IPR024811:Polycomb protein ASX/ASX-like, IPR026905:Protein ASX-like, PHD domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR028020:ASX homology domain" CG8787 11-Aug-17 DroID_v2017_08 "Drer\asxl2, Drer\asxl1" - - "Xtro\asxl2, Xtro\asxl3" "Mmus\Asxl3, Mmus\Asxl1, Mmus\Asxl2" "Hsap\ASXL1, Hsap\ASXL3, Hsap\ASXL2" " embryonic stage -- adult stage , embryonic stage | blastoderm , embryonic stage | stage >5 , adult stage && oogenesis stage , embryonic stage " "

anterior ,

posterior , organism | ubiquitous

, nurse cell

, ventral neurogenic region

, central nervous system

" " embryonic stage , embryonic stage | stage >=5 " " central nervous system

, ventral neurogenic region

, organism

" FBgn0033153 Gadd45 Growth arrest and DNA damage-inducible 45 http://flybase.org/reports/FBgn0033153 protein_coding_gene - activation of MAPKKK activity ; GO:0000185 | inferred from biological aspect of ancestor with PANTHER:PTN000823659 regulation of cell cycle ; GO:0051726 | inferred from biological aspect of ancestor with PANTHER:PTN000823659 JNK cascade ; GO:0007254 | inferred from genetic interaction with hep regulation of oviposition ; GO:0046662 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000823659 "CG11086, GADD45, BcDNA:RH70774, Gadd45, D-GADD45, GG1086" "IPR004038:Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR029064:50S ribosomal protein L30e-like, IPR024824:Growth arrest and DNA damage-inducible protein GADD45" CG11086 11-Aug-17 DroID_v2017_08 "Drer\gadd45ba, Drer\gadd45aa, Drer\gadd45gb.1, Drer\gadd45ab, Drer\rps12, Drer\gadd45bb, Drer\LOC797032, Drer\gadd45ga" - - "Xtro\gadd45a, Xtro\gadd45g, Xtro\gadd45b" "Mmus\Gadd45a, Mmus\Gadd45g, Mmus\Gadd45b" "Hsap\RPS12, Hsap\GADD45B, Hsap\GADD45G, Hsap\GADD45A" "lethal,long lived,locomotor rhythm defective,RU486 conditional,viable" "egg chamber,nurse cell,follicle cell,dorsal appendage,chorion" FBgn0032151 nAChRalpha6 nicotinic Acetylcholine Receptor alpha6 http://flybase.org/reports/FBgn0032151 protein_coding_gene acetylcholine-gated cation channel activity ; GO:0022848 | contributes_to inferred from direct assay acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity "synaptic transmission, cholinergic ; GO:0007271 | inferred from mutant phenotype response to insecticide ; GO:0017085 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from direct assay muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype" "postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394 integral component of membrane ; GO:0016021 | inferred from direct assay acetylcholine-gated channel complex ; GO:0005892 | inferred from physical interaction with nAChRα5, nAChRα7 acetylcholine-gated channel complex ; GO:0005892 | inferred from direct assay acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity" "Dalpha6, nAChR, CG4128, CT13662, nAcRalpha-30D, BcDNA:GH01410, rsn, nAChRalpha, nAChR alpha 6, alpha6, das, nAChRalpha-30D, nAChRalpha6, nAChRAlpha-30D, nAChR-alpha30D" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG4128 11-Aug-17 DroID_v2017_08 "Drer\chrnb1l, Drer\chrnb3a, Drer\chrnb1, Drer\chrnb2b, Drer\chrne, Drer\chrna9, Drer\chrnb3b, Drer\chrna2b, Drer\htr3b, Drer\chrna10a, Drer\chrna4b, Drer\chrna1, Drer\si:ch211-256e16.4, Drer\chrng, Drer\LOC101882451, Drer\chrna3, Drer\chrna6, Drer\htr3a, Drer\chrna5, Drer\si:ch211-39a7.1, Drer\chrna2a, Drer\LOC798522, Drer\chrnb2l, Drer\chrna7, Drer\chrnb4, Drer\si:ch73-380n15.2, Drer\chrnd" - "Cele\acr-14, Cele\acr-10, Cele\acr-21, Cele\acr-2, Cele\acr-3, Cele\lgc-4, Cele\lev-1, Cele\acr-9, Cele\acr-16, Cele\acr-8, Cele\acr-7, Cele\acr-6, Cele\acr-19, Cele\unc-38, Cele\unc-63, Cele\W10G11.17, Cele\acr-15, Cele\acr-25, Cele\eat-2, Cele\acr-11, Cele\acr-12" "Xtro\chrnb2, Xtro\chrna1.2, Xtro\chrnb3, Xtro\chrne, Xtro\chrna6, Xtro\chrna2, Xtro\chrna7, Xtro\chrna9, Xtro\chrng, Xtro\chrna1, Xtro\chrna5, Xtro\chrnd" "Mmus\Chrnb1, Mmus\Chrna6, Mmus\Chrna3, Mmus\Chrna1, Mmus\Chrna2, Mmus\Chrna9, Mmus\Chrna4, Mmus\Chrnb2, Mmus\Chrne, Mmus\Htr3a, Mmus\Chrnb4, Mmus\Chrna5, Mmus\Chrna10, Mmus\Chrng, Mmus\Chrnb3, Mmus\Chrnd, Mmus\Chrna7, Mmus\Htr3b" "Hsap\CHRNB3, Hsap\CHRNB4, Hsap\HTR3D, Hsap\HTR3B, Hsap\HTR3A, Hsap\CHRNG, Hsap\CHRNA10, Hsap\HTR3E, Hsap\CHRNA9, Hsap\CHRNB2, Hsap\HTR3C, Hsap\CHRNB1, Hsap\CHRNA1, Hsap\CHRNA4, Hsap\CHRNA3, Hsap\CHRNA2, Hsap\CHRNA5, Hsap\CHRFAM7A, Hsap\CHRNA7, Hsap\CHRNA6, Hsap\CHRND, Hsap\CHRNE" "chemical resistant,viable,fertile,neurophysiology defective,lethal" ventral nerve cord FBgn0035625 Blimp-1 Blimp-1 http://flybase.org/reports/FBgn0035625 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay" "cellular response to ecdysone ; GO:0071390 | inferred from expression pattern regulation of tube architecture, open tracheal system ; GO:0035152 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay pupation ; GO:0035074 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "CG5249, Blimp-1, dBlimp-1, blimp-1, dBlimp1, BLIMP-1" "IPR013087:Zinc finger C2H2-type, IPR001214:SET domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5249 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-66i24.9, Drer\si:dkey-66i24.8, Drer\prdm1c, Drer\si:dkeyp-41f9.4, Drer\prdm1a, Drer\prdm8, Drer\prdm4, Drer\prdm8b, Drer\prdm5, Drer\prdm2a" "Scer\MIG3, Scer\AZF1" "Cele\set-17, Cele\blmp-1" "Xtro\prdm4, Xtro\prdm6, Xtro\prdm1, Xtro\prdm8, Xtro\prdm5" "Mmus\Prdm6, Mmus\Prdm5, Mmus\Prdm8, Mmus\Prdm1, Mmus\Prdm4, Mmus\Prdm2" "Hsap\PRDM2, Hsap\PRDM1, Hsap\PRDM6, Hsap\PRDM4, Hsap\PRDM8, Hsap\PRDM7, Hsap\ZNF683, Hsap\PRDM5" "lethal - all die before end of pupal stage,some die during pupal stage" dorsal trunk primordium FBgn0029848 Btnd Biotinidase http://flybase.org/reports/FBgn0029848 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ; GO:0016811 | inferred from electronic annotation with InterPro:IPR012101 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from biological aspect of ancestor with PANTHER:PTN000064607" nitrogen compound metabolic process ; GO:0006807 | inferred from electronic annotation with InterPro:IPR003010 histone biotinylation ; GO:0071110 | inferred from mutant phenotype peptidyl-lysine biotinylation ; GO:0018054 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype - "CT12113, CG3599, Btnd, Btd, BTD" "IPR003010:Carbon-nitrogen hydrolase, IPR012101:Biotinidase, eukaryotic" CG3599 11-Aug-17 DroID_v2017_08 "Drer\btd, Drer\nit2" "Scer\NIT3, Scer\NTA1" - "Xtro\vnn1, Xtro\nit2, Xtro\btd" "Mmus\Vnn3, Mmus\Nit2, Mmus\Vnn1, Mmus\Btd" "Hsap\NIT2, Hsap\VNN1, Hsap\VNN2, Hsap\VNN3, Hsap\BTD" "short lived,heat stress response defective,male limited,partially lethal - majority die,some die during pupal stage,lethal,recessive" FBgn0265784 CrebB Cyclic-AMP response element binding protein B http://flybase.org/reports/FBgn0265784 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001630, InterPro:IPR004827 DNA binding ; GO:0003677 | inferred from mutant phenotype sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein dimerization activity ; GO:0046983 | inferred from sequence or structural similarity" "thermosensory behavior ; GO:0040040 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from direct assay long-term memory ; GO:0007616 | inferred from expression pattern positive regulation of feeding behavior ; GO:2000253 | inferred from genetic interaction with sNPF-R sleep ; GO:0030431 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype long-term memory ; GO:0007616 | traceable author statement learning or memory ; GO:0007611 | non-traceable author statement locomotor rhythm ; GO:0045475 | non-traceable author statement circadian rhythm ; GO:0007623 | traceable author statement medium-term memory ; GO:0072375 | inferred from mutant phenotype regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | traceable author statement rhythmic behavior ; GO:0007622 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "CREB, dCREB2-b, Creb B 17A, CG6103, CrebB-17A, dCREB2, CrebB, Creb2b, CREB2b, Creb17A, dCrebB2, CREB-b, CREB-B, CREB2a, Creb, dCREB2b, CREB2, dCREB, CrebB17-A, dCbz, dCREB-B, dCREB2-a, S162, dCREB-2a, dCREB2a, l(1)17Af, dcreb2-b, dCreb2-b, dCreb2, Creb2-b, Creb2, Creb2.b, dCREB-2, CrebB-17B, CRE-BP, DM9" "IPR001630:cAMP response element binding (CREB) protein, IPR003102:Coactivator CBP, pKID, IPR004827:Basic-leucine zipper domain" CG6103 11-Aug-17 DroID_v2017_08 "Drer\fosab, Drer\creb1a, Drer\creb1b, Drer\cremb, Drer\atf1, Drer\creb5b, Drer\fosl2, Drer\crema, Drer\fosl1a, Drer\atf2" "Scer\ACA1, Scer\SKO1" "Cele\crh-1, Cele\fos-1" "Xtro\fosl2, Xtro\creb1, Xtro\atf1" "Mmus\Fosl1, Mmus\Fosl2, Mmus\Crem, Mmus\Atf7, Mmus\Creb1, Mmus\Atf1, Mmus\Fos, Mmus\Tusc1, Mmus\Creb5" "Hsap\FOSL1, Hsap\CREM, Hsap\FOS, Hsap\ATF2, Hsap\ATF1, Hsap\FOSL2, Hsap\TUSC1, Hsap\CREB5, Hsap\CREB1, Hsap\ATF7" " adult stage , embryonic stage&&larval stage&&pupal stage&&adult stage " adult head

DRSC20232 EK 1.171535118 -0.238027572 1.798951786 0.01912478 1.411067395 1.552254913 FBgn0027525 LTV1 LTV1 ribosome biogenesis factor http://flybase.org/reports/FBgn0027525 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VS38 inferred from physical interaction with UniProtKB:Q9W5P1 positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype ribosomal small subunit export from nucleus ; GO:0000056 | inferred from mutant phenotype cell growth ; GO:0016049 | inferred from mutant phenotype rRNA processing ; GO:0006364 | inferred from mutant phenotype ribosomal small subunit biogenesis ; GO:0042274 | inferred from mutant phenotype "EGO complex ; GO:0034448 | inferred from biological aspect of ancestor with PANTHER:PTN000488416 late endosome membrane ; GO:0031902 | inferred from biological aspect of ancestor with PANTHER:PTN000488416 cytosolic small ribosomal subunit ; GO:0022627 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000488416 preribosome, small subunit precursor ; GO:0030688 | inferred from biological aspect of ancestor with PANTHER:PTN000488416" "BcDNA:LD21529, LTV1, CG7686" IPR007307:Low temperature viability protein CG7686 11-Aug-17 DroID_v2017_08 Drer\ltv1 Scer\LTV1 Cele\T23D8.3 Xtro\ltv1 Mmus\Ltv1 Hsap\LTV1 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0051116 ClC-a Chloride channel-a http://flybase.org/reports/FBgn0051116 protein_coding_gene voltage-gated chloride channel activity ; GO:0005247 | inferred from biological aspect of ancestor with PANTHER:PTN001363397 chloride channel activity ; GO:0005254 | inferred from mutant phenotype transepithelial chloride transport ; GO:0030321 | inferred from mutant phenotype renal water homeostasis ; GO:0003091 | inferred from mutant phenotype chloride transmembrane transport ; GO:1902476 | inferred from mutant phenotype transepithelial water transport ; GO:0035377 | inferred from mutant phenotype chloride transport ; GO:0006821 | inferred from sequence or structural similarity with UniProtKB:Q9NZA1 renal water transport ; GO:0003097 | inferred from mutant phenotype basal plasma membrane ; GO:0009925 | inferred from direct assay actin cytoskeleton ; GO:0015629 | inferred from sequence or structural similarity with UniProtKB:Q9NZA1 apical plasma membrane ; GO:0016324 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay "FBgn0037951, CG6942, CG14726, ClC-a, DmClCa, DmClC-a, CG31116, DmClC-2, Clc-a, CLC-2" "IPR000644:CBS domain, IPR001807:Chloride channel, voltage gated, IPR014743:Chloride channel, core" CG31116 11-Aug-17 DroID_v2017_08 "Drer\clcn2a, Drer\clcnk, Drer\clcn2c, Drer\clcn1b, Drer\clcn1a, Drer\clcn2b" Scer\GEF1 "Cele\clh-3, Cele\clh-1, Cele\clh-2, Cele\clh-4" "Xtro\clcn2, Xtro\clcnkb" "Mmus\Clcn1, Mmus\Clcnka, Mmus\Clcn2, Mmus\Clcnkb" "Hsap\CLCNKB, Hsap\CLCNKA, Hsap\CLCN1, Hsap\CLCN2" FBgn0050037 CG30037 - http://flybase.org/reports/FBgn0050037 protein_coding_gene galactosyltransferase activity ; GO:0008378 | inferred from electronic annotation with InterPro:IPR002659 protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR002659 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "CG8976, CG30037" "IPR002659:Glycosyl transferase, family 31" CG30037 11-Aug-17 DroID_v2017_08 "Drer\b3galt1b, Drer\LOC565422, Drer\zgc:194330, Drer\si:ch211-126g16.11, Drer\b3gnt7, Drer\si:dkey-175m17.6, Drer\b3gnt2b, Drer\si:dkey-160o24.3, Drer\b3gnt5a, Drer\zgc:194551, Drer\zgc:86586, Drer\b3galt1a, Drer\si:dkeyp-98a7.1, Drer\b3galnt2, Drer\b3gnt7l, Drer\b3gnt3, Drer\b3gnt5b, Drer\b3gnt2l, Drer\b3galt2, Drer\b3gnt9, Drer\LOC100535930, Drer\b3gnt2a" - "Cele\C47F8.6, Cele\B0024.15, Cele\bus-2" "Xtro\b3galt2, Xtro\LOC100494668, Xtro\b3galt1, Xtro\b3gnt2, Xtro\b3gnt5, Xtro\b3gnt4, Xtro\LOC100494986, Xtro\LOC100493833, Xtro\b3galt4, Xtro\b3galnt2, Xtro\LOC100487553, Xtro\b3gnt3, Xtro\LOC100489267, Xtro\b3gnt6, Xtro\b3gnt3" "Mmus\B3gnt8, Mmus\B3gnt2, Mmus\B3galt5, Mmus\B3galt2, Mmus\B3gnt7, Mmus\B3galt4, Mmus\B3gnt5, Mmus\B3gnt9, Mmus\B3gnt3, Mmus\B3gnt4, Mmus\B3galnt2, Mmus\B3gnt6, Mmus\B3galt1, Mmus\B3galnt1" "Hsap\B3GNT6, Hsap\B3GALT4, Hsap\B3GNT8, Hsap\B3GALT2, Hsap\B3GALT5, Hsap\B3GALNT1, Hsap\B3GNT7, Hsap\B3GNT4, Hsap\B3GNT9, Hsap\B3GNT3, Hsap\B3GALNT2, Hsap\B3GNT2, Hsap\B3GNT5, Hsap\B3GALT1" viable FBgn0031930 CG7025 - http://flybase.org/reports/FBgn0031930 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG7025 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG7025 11-Aug-17 DroID_v2017_08 "Drer\cpa2, Drer\cpa1, Drer\cpa6, Drer\cpb1, Drer\cpb2, Drer\cpa5, Drer\cpo, Drer\cpa4" Scer\ECM14 "Cele\F02D8.4, Cele\Y59C2A.1, Cele\W01A8.6, Cele\ZC434.9, Cele\Y47G6A.19, Cele\T06A4.1, Cele\T06A4.3, Cele\Y18H1A.9, Cele\suro-1" "Xtro\cpb1, Xtro\cpa3, Xtro\cpb2, Xtro\LOC100487462, Xtro\cpo, Xtro\cpa1" "Mmus\Cpb2, Mmus\Cpa1, Mmus\Cpa3, Mmus\Cpa5, Mmus\Cpa4, Mmus\Cpa2, Mmus\Cpb1, Mmus\Cpa6" "Hsap\CPA1, Hsap\CPB2, Hsap\CPO, Hsap\CPA2, Hsap\CPA6, Hsap\CPA5, Hsap\CPA3, Hsap\CPA4, Hsap\CPB1" viable FBgn0004867 RpS2 Ribosomal protein S2 http://flybase.org/reports/FBgn0004867 "FBgn0010266, FBgn0013522, FBgn0022202, FBgn0025306" protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR013810 structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000851, InterPro:IPR005324, InterPro:IPR005711, InterPro:IPR013810 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" small ribosomal subunit ; GO:0015935 | inferred from electronic annotation with InterPro:IPR005711 nuclear chromosome ; GO:0000228 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement nucleolus ; GO:0005730 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "RpS2, S2, dS2, Dm01335, l(2)k04603, l(2)03848, anon-EST:Posey202, CG5920, sop, Rp S2" "IPR018192:Ribosomal protein S5, N-terminal, conserved site, IPR000851:Ribosomal protein S5, IPR005324:Ribosomal protein S5, C-terminal, IPR005711:Ribosomal protein S5, eukaryotic/archaeal, IPR013810:Ribosomal protein S5, N-terminal, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold" CG5920 11-Aug-17 DroID_v2017_08 Drer\rps2 Scer\RPS2 Cele\rps-2 Xtro\rps2 Mmus\Rps2 Hsap\RPS2 " oogenesis stage && adult stage | female , oogenesis stage , adult stage | female , adult stage && oogenesis stage , embryonic stage " " ovary

,

ubiquitous , nurse cell

" "visible,partially lethal - majority die,lethal,recessive,female sterile,lethal - all die before end of larval stage,some die during larval stage" "anterior crossvein,wing,macrochaeta,stage S5 oocyte,ovary" DRSC03614 IEK -1.480544164 -1.946626878 3.165610992 -5.606791895 1.395854719 3.029395701 FBgn0037391 CG2017 - http://flybase.org/reports/FBgn0037391 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795 - - "CG 2017, CG2017" "IPR000795:Transcription factor, GTP-binding domain, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2017 11-Aug-17 DroID_v2017_08 "Drer\gtpbp1l, Drer\gtpbp1, Drer\gtpbp2" Scer\HBS1 "Cele\T04H1.2, Cele\cgp-1" "Xtro\gtpbp1, Xtro\gtpbp2" "Mmus\Gtpbp1, Mmus\Gtpbp2" "Hsap\GTPBP2, Hsap\GTPBP1" "viable,fertile,neuroanatomy defective" "anterior fascicle & synapse,intersegmental nerve" FBgn0000557 eEF1alpha2 eukaryotic translation elongation factor 1 alpha 2 http://flybase.org/reports/FBgn0000557 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR004539 translation elongation factor activity ; GO:0003746 | inferred from biological aspect of ancestor with PANTHER:PTN000562490 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000561878 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity" translational elongation ; GO:0006414 | inferred from electronic annotation with InterPro:IPR004539 translational elongation ; GO:0006414 | inferred from sequence or structural similarity neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004539 lipid particle ; GO:0005811 | inferred from direct assay eukaryotic translation elongation factor 1 complex ; GO:0005853 | inferred from sequence or structural similarity "ef-1alpha, Ef1 alpha100E, CG1873, eEF1alpha, EF1alpha, EF1-alpha, Ef1a48, EF-1alpha, EF-1, EF-1alpha F2, Efla2, F2, Ef1alpha100E, Ef1alpha2, EF1alpha100, EF1a, Ef1a-100E, EF1-a 100E, eEF1alpha2, EF1A" "IPR000795:Transcription factor, GTP-binding domain, IPR004160:Translation elongation factor EFTu/EF1A, C-terminal, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR004539:Translation elongation factor EF1A, eukaryotic/archaeal, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031157:Tr-type G domain, conserved site" CG1873 11-Aug-17 DroID_v2017_08 "Drer\eef1a2, Drer\eef1a1l2, Drer\si:dkey-37o8.1, Drer\eef1a1l1, Drer\eef1a1a, Drer\eef1a1b" "Scer\TEF1, Scer\TEF2" "Cele\eef-1A.1, Cele\eef-1A.2" "Xtro\42Sp50, Xtro\eef1a1o, Xtro\eef1a2, Xtro\eef1a1" "Mmus\Eef1a1, Mmus\Eef1a2" "Hsap\EEF1A2, Hsap\EEF1A1" " pupal stage | late , adult stage " "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0031437 Arpc5 "Actin-related protein 2/3 complex, subunit 5" http://flybase.org/reports/FBgn0031437 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with HGNC:708 actin binding ; GO:0003779 | inferred from sequence or structural similarity actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000291131 Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from sequence or structural similarity with HGNC:708 cell migration ; GO:0016477 | inferred from biological aspect of ancestor with PANTHER:PTN000974138 phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from biological aspect of ancestor with PANTHER:PTN000291131 Arp2/3 protein complex ; GO:0005885 | inferred from biological aspect of ancestor with PANTHER:PTN000291131 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000291131 lamellipodium ; GO:0030027 | inferred from direct assay Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with HGNC:708 "P16-ARC, CG9881, p16-ARC, p16, ArpC5, Arpc5, ARPC5, p16-arc" IPR006789:Actin-related protein 2/3 complex subunit 5 CG9881 11-Aug-17 DroID_v2017_08 "Drer\arpc5la, Drer\arpc5lb, Drer\arpc5b, Drer\arpc5a" Scer\ARC15 "Cele\arx-7, Cele\C46H11.3" "Xtro\arpc5, Xtro\arpc5l" "Mmus\Arpc5, Mmus\Arpc5l" "Hsap\ARPC5, Hsap\ARPC5L" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033474 CG1407 - http://flybase.org/reports/FBgn0033474 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 plasma membrane ; GO:0005886 | inferred from direct assay CG1407 "IPR001594:Palmitoyltransferase, DHHC domain, IPR030293:Palmitoyltransferase ZDHHC15" CG1407 11-Aug-17 DroID_v2017_08 "Drer\zdhhc2, Drer\zdhhc20a, Drer\zdhhc20b, Drer\zdhhc15a, Drer\zdhhc15b" "Scer\PFA3, Scer\PFA4, Scer\PFA5" "Cele\dhhc-4, Cele\dhhc-5, Cele\dhhc-1, Cele\spe-10" "Xtro\zdhhc15, Xtro\pqlc2l, Xtro\zdhhc2, Xtro\zdhhc20" "Mmus\Zdhhc15, Mmus\Zdhhc20, Mmus\Zdhhc2" "Hsap\ZDHHC20, Hsap\ZDHHC2, Hsap\ZDHHC15" "viable,fertile" FBgn0023174 Prosbeta2 Proteasome beta2 subunit http://flybase.org/reports/FBgn0023174 "FBgn0002419, FBgn0025245, FBgn0025254" protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | inferred from sequence or structural similarity with SGD:S000005683 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000005683 "proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay proteasome core complex, beta-subunit complex ; GO:0019774 | inferred from sequence or structural similarity with SGD:S000005683" "DTS7, Prosbeta2, beta2_dm, beta2, l(3)DTS7, DTS-7, anon-EST:fe1G6, anon-EST:fe1E6, CG3329, prosbeta2, prosbeta, b2, Prosbeta, Dts7, 3329, Prosbeta 2, Beta-2, beta 2, PROSbeta2, beta-2" "IPR000243:Peptidase T1A, proteasome beta-subunit, IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR023333:Proteasome B-type subunit, IPR024689:Proteasome beta subunit, C-terminal, IPR029055:Nucleophile aminohydrolases, N-terminal" CG3329 11-Aug-17 DroID_v2017_08 "Drer\psmb10, Drer\psmb7, Drer\zgc:92791" Scer\PUP1 Cele\pbs-2 "Xtro\psmb7.2, Xtro\psmb7" "Mmus\Psmb7, Mmus\Psmb10" "Hsap\PSMB10, Hsap\PSMB7" embryonic stage -- adult stage "neuroanatomy defective,wild-type,lethal,dominant,heat sensitive,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere of eye photoreceptor cell,macrochaeta,microchaeta,tormogen cell,ectopic,thecogen cell,trichogen cell,eo neuron,imaginal disc,heat sensitive,adult abdomen,wing vein,eye,ommatidium,multivesicular body | supernumerary | heat sensitiveGMR.PF,autophagic vacuole | supernumerary | heat sensitiveGMR.PF,eye photoreceptor cell" DRSC11257 IEK -2.22680727 -2.148158293 -1.43370878 -3.617696514 0.731796467 1.771613459 FBgn0027259 Kmn1 kinetochore Mis12-Ndc80 network component 1 http://flybase.org/reports/FBgn0027259 "FBgn0030312, FBgn0066829" protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype mitotic chromosome movement towards spindle pole ; GO:0007079 | inferred from mutant phenotype kinetochore ; GO:0000776 | inferred from direct assay Ndc80 complex ; GO:0031262 | inferred from direct assay NMS complex ; GO:0031617 | inferred from sequence or structural similarity with HGNC:24548 "CG1558, CT4038, anon-WO03040301.201, Nsl1, Kmn1, l(1)G0237, dmNsl1R, nsl1" - CG1558 11-Aug-17 DroID_v2017_08 - - - - - - "mitotic cell cycle defective,viable,fertile,uncoordinated,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "condensed nuclear chromosome,metaphase,nucleus,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0001222 Hsf Heat shock factor http://flybase.org/reports/FBgn0001222 "FBgn0010529, FBgn0020929" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with MED17" "response to heat ; GO:0009408 | inferred from direct assay positive regulation of DNA binding ; GO:0043388 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype inferred from genetic interaction with Trl response to heat ; GO:0009408 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "HSF, dHSF, hsf, CG5748, l(2)03091, DmHSF, Dm-Hsf, D-HSF, Hsf, DmHSFa, HSFa, HSF1, dHSFa, Hsf1, heat shock factor" "IPR000232:Heat shock factor (HSF)-type, DNA-binding, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR027725:Heat shock transcription factor family, IPR010542:Vertebrate heat shock transcription factor, C-terminal domain, IPR027072:Heat shock factor protein 1" CG5748 11-Aug-17 DroID_v2017_08 "Drer\hsf4, Drer\si:dkey-18a10.3, Drer\hsf2, Drer\hsf1" "Scer\HMS2, Scer\MGA1, Scer\SFL1, Scer\SKN7, Scer\HSF1" Cele\hsf-1 "Xtro\hsf2, Xtro\hsf1, Xtro\hsf3" "Mmus\Hsf3, Mmus\Hsf4, Mmus\Hsfy2, Mmus\Hsf1, Mmus\Hsf2" "Hsap\HSFX1, Hsap\HSFY1, Hsap\HSF4, Hsap\HSFX2, Hsap\HSF2, Hsap\HSFY2, Hsap\HSF1" "lethal,recessive,increased mortality,wild-type,female sterile,stress response defective,dominant,female sterile germline-dependent,germline clone,lethal - all die before end of larval stage,some die during larval stage,fertile,viable,heat stress response defective,heat sensitive,immune response defective,neurophysiology defective,neuroanatomy defective" "salivary gland,egg chamber,nurse cell,polytene chromosome,ganglion mother cell" FBgn0013726 pnut peanut http://flybase.org/reports/FBgn0013726 "FBgn0010304, FBgn0010515" protein_coding_gene GTPase activity ; GO:0003924 | inferred from direct assay ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with park microtubule binding ; GO:0008017 | inferred from direct assay GTP binding ; GO:0005525 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q0E908 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y103 actin binding ; GO:0003779 | inferred from direct assay mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from direct assay cellularization ; GO:0007349 | traceable author statement actomyosin contractile ring assembly ; GO:0000915 | non-traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from sequence or structural similarity apoptotic process ; GO:0006915 | inferred from genetic interaction with hid inferred from genetic interaction with rpr inferred from genetic interaction with grim "mitochondrion ; GO:0005739 | inferred from direct assay septin complex ; GO:0031105 | inferred from physical interaction with Sep1, Sep2 septin complex ; GO:0031105 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay intercellular bridge ; GO:0045171 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay contractile ring ; GO:0070938 | inferred from direct assay septin ring ; GO:0005940 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay" "CG8705, clone 2.18, Pnut, E(sina)8, l(2)02502, anon-EST:Liang-2.18, E(sina)44C, pnut, PNUT, Peanut, dSEPT7" "IPR016491:Septin, IPR030379:Septin-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8705 11-Aug-17 DroID_v2017_08 "Drer\zgc:63587, Drer\sept4b, Drer\sept5a, Drer\sept2, Drer\sept10, Drer\zgc:162239, Drer\sept5b, Drer\sept3, Drer\sept15, Drer\sept12, Drer\sept8a, Drer\sept4a, Drer\sept7b, Drer\sept6, Drer\sept8b, Drer\sept7a" "Scer\SHS1, Scer\CDC12, Scer\SPR28, Scer\CDC11, Scer\CDC3, Scer\SPR3, Scer\CDC10" "Cele\unc-61, Cele\C18B2.5, Cele\unc-59" "Xtro\sept5, Xtro\sept11, Xtro\sept6, Xtro\sept2, Xtro\sept10, Xtro\sept7, Xtro\sept8" "Mmus\Sept1, Mmus\Sept10, Mmus\Sept4, Mmus\Sept9, Mmus\Sept6, Mmus\Sept2, Mmus\Sept5, Mmus\Sept14, Mmus\Sept7, Mmus\Sept11, Mmus\Sept8, Mmus\Sept12, Mmus\Sept3" "Hsap\SEPT3, Hsap\SEPT8, Hsap\SEPT7, Hsap\SEPT4, Hsap\SEPT11, Hsap\SEPT10, Hsap\SEPT5, Hsap\SEPT12, Hsap\SEPT6, Hsap\C9orf69, Hsap\SEPT2, Hsap\SEPT1, Hsap\SEPT14, Hsap\SEPT9" " larval stage | third instar , embryonic stage , adult stage " " photoreceptor cell | presumptive

, central nervous system

, follicle cell | basal " "lethal,recessive,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,viable,fertile,wild-type,cytokinesis defective,lethal - all die before end of pupal stage,some die during pupal stage,visible,partially lethal - majority die" "egg,germline clone,germarium region 1,embryonic/first instar larval cuticle,denticle belt,embryonic head,actin filament | embryonic stage | germline clone,ventral furrow & actin filament | germ-line clone,nucleus | embryonic stage | germline clone,dorsal appendage,imaginal disc,follicle cell,embryonic/larval lymph gland,imaginal ring,salivary gland common duct primordium,photoreceptor cell R7,trichogen cell" DRSC07666 E 0.285944396 0.09011778 1.721196849 0.002320368 -0.211837567 -0.153926941 FBgn0011267 sbn scatterbrained http://flybase.org/reports/FBgn0011267 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available sbn - - 11-Aug-17 DroID_v2017_08 - - - - - - "developmental rate defective,non-rescuable maternal effect" FBgn0014261 l(2)N7-8 lethal (2) N7-8 http://flybase.org/reports/FBgn0014261 - gene - - - "N7-8, l(2)N7-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0263873 sick sickie http://flybase.org/reports/FBgn0263873 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 actin filament organization ; GO:0007015 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype - "sick, CG43720, CG34343, CG42589, sickie, CG10662, CG13960, CG13961, CG13959, CG33316, CG13964, CG13958, Dm_2L:104545" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003959:ATPase, AAA-type, core, IPR003593:AAA+ ATPase domain, IPR001715:Calponin homology domain" CG43720 11-Aug-17 DroID_v2017_08 "Drer\nav3, Drer\nav1a, Drer\nav2a, Drer\nav1b, Drer\nav2b" - Cele\unc-53 "Xtro\nav1, Xtro\nav2" "Mmus\Nav2, Mmus\Nav3, Mmus\Nav1" "Hsap\NAV1, Hsap\NAV2, Hsap\NAV3" FBgn0020762 Atet ABC transporter expressed in trachea http://flybase.org/reports/FBgn0020762 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from direct assay cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" neurogenesis ; GO:0022008 | inferred from mutant phenotype transmembrane transport ; GO:0055085 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 integral component of plasma membrane ; GO:0005887 | inferred from direct assay exocytic vesicle membrane ; GO:0099501 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CG2969, Atet" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG2969 11-Aug-17 DroID_v2017_08 "Drer\abcg2b, Drer\abcg8, Drer\abcg5, Drer\abcg1, Drer\abcg4a, Drer\abcg4b, Drer\abcg2a" "Scer\YOL075C, Scer\ADP1, Scer\PDR10, Scer\PDR15" "Cele\wht-4, Cele\abch-1" "Xtro\abcg8, Xtro\abcg5, Xtro\abcg4" "Mmus\Abcg4, Mmus\Abcg3, Mmus\Abcg2, Mmus\Abcg8, Mmus\Abcg5, Mmus\Abcg1" "Hsap\ABCG8, Hsap\ABCG4, Hsap\ABCG5, Hsap\ABCG1" "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC00263 I 1.661073175 1.032050378 0.49406365 0.195466716 -0.058499371 0.925317355 FBgn0051961 TBCC Tubulin-binding cofactor C http://flybase.org/reports/FBgn0051961 protein_coding_gene "tubulin binding ; GO:0015631 | inferred from electronic annotation with InterPro:IPR027684, InterPro:IPR031925" post-chaperonin tubulin folding pathway ; GO:0007023 | inferred from electronic annotation with InterPro:IPR027684 neurogenesis ; GO:0022008 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000388691 tubulin complex assembly ; GO:0007021 | inferred from biological aspect of ancestor with PANTHER:PTN000388691 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000388691 "CG3381, BcDNA:LD34582, TBCC, CG31961" "IPR006599:CARP motif, IPR012945:Tubulin binding cofactor C-like domain, IPR017901:C-CAP/cofactor C-like domain, IPR027684:Tubulin-specific chaperone C, IPR031925:Tubulin-specific chaperone C, N-terminal" CG31961 11-Aug-17 DroID_v2017_08 "Drer\tbcc, Drer\rp2" - "Cele\rpi-2, Cele\tbcc-1" "Xtro\tbcc, Xtro\rp2" "Mmus\Tbcc, Mmus\Rp2" "Hsap\RP2, Hsap\TBCC" "viable,fertile,lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,tormogen cell" FBgn0085412 CG34383 - http://flybase.org/reports/FBgn0085412 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG34383, CG14365, CG14366, CG9322, Dm_3R:52023" "IPR011993:PH domain-like, IPR001849:Pleckstrin homology domain" CG34383 11-Aug-17 DroID_v2017_08 "Drer\ppp1r9ba, Drer\pdzph1, Drer\plekha6, Drer\si:ch211-234p6.5, Drer\ppp1r9a, Drer\cnksr1, Drer\plekha5, Drer\plekha7b, Drer\plekha7a" "Scer\BOI1, Scer\BOI2" Cele\nab-1 "Xtro\plekha4, Xtro\plekha7, Xtro\plekha6" "Mmus\Ipcef1, Mmus\Plekha5, Mmus\Ppp1r9a, Mmus\Plekha4, Mmus\Ppp1r9b, Mmus\Plekha6, Mmus\Pdzph1, Mmus\Cnksr1, Mmus\Plekha7" "Hsap\CNKSR1, Hsap\PPP1R9A, Hsap\PPP1R9B, Hsap\PLEKHA4, Hsap\PLEKHA6, Hsap\PLEKHA7, Hsap\PLEKHA5" FBgn0038045 NANS N-acetylneuraminic acid synthase http://flybase.org/reports/FBgn0038045 protein_coding_gene N-acylneuraminate-9-phosphate synthase activity ; GO:0047444 | inferred from direct assay carbohydrate biosynthetic process ; GO:0016051 | inferred from electronic annotation with InterPro:IPR013132 glycosylation ; GO:0070085 | inferred from mutant phenotype - "CG5232, DmSAS, Neu5Ac, NANS, Sas, SAS, sas" "IPR006190:Antifreeze-like/N-acetylneuraminic acid synthase C-terminal, IPR013132:N-acetylneuraminic acid synthase, N-terminal, IPR013785:Aldolase-type TIM barrel, IPR013974:SAF domain" CG5232 11-Aug-17 DroID_v2017_08 "Drer\nansa, Drer\nansb" - - Xtro\nans Mmus\Nans Hsap\NANS "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0031598 Vps53 Vacuolar protein sorting 53 http://flybase.org/reports/FBgn0031598 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "endocytic recycling ; GO:0032456 | inferred from sequence or structural similarity with HGNC:25608 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN000302300" GARP complex ; GO:0000938 | inferred from sequence or structural similarity with HGNC:25608 GARP complex ; GO:0000938 | inferred from biological aspect of ancestor with PANTHER:PTN000302300 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:25608 "Vps53, CG3338" "IPR007234:Vps53-like, N-terminal" CG3338 11-Aug-17 DroID_v2017_08 Drer\vps53 Scer\VPS53 Cele\vps-53 Xtro\vps53 Mmus\Vps53 Hsap\VPS53 viable FBgn0086348 se sepia http://flybase.org/reports/FBgn0086348 protein_coding_gene "glutathione dehydrogenase (ascorbate) activity ; GO:0045174 | inferred from direct assay glutathione transferase activity ; GO:0004364 | inferred from direct assay transferase activity, transferring sulfur-containing groups ; GO:0016782 | inferred from direct assay pyrimidodiazepine synthase activity ; GO:0004734 | inferred from direct assay inferred from genetic interaction with se protein homodimerization activity ; GO:0042803 | inferred from physical interaction with se pyrimidodiazepine synthase activity ; GO:0004734 | inferred from mutant phenotype" eye pigment biosynthetic process ; GO:0006726 | inferred from genetic interaction with se pteridine biosynthetic process ; GO:0006728 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "se, CG6781, cg6781, GSTO1, dmgsto1, GSTO4, DmGSTO4" "IPR012336:Thioredoxin-like fold, IPR010987:Glutathione S-transferase, C-terminal-like, IPR005442:Glutathione S-transferase, omega-class, IPR004045:Glutathione S-transferase, N-terminal" CG6781 11-Aug-17 DroID_v2017_08 "Drer\gsto2, Drer\gsto1, Drer\gstr" Scer\GTT2 "Cele\gst-44, Cele\gsto-1, Cele\gsto-3, Cele\C02D5.4, Cele\gsto-2" "Xtro\gsto1, Xtro\gsto2, Xtro\LOC100498493" "Mmus\Gsto2, Mmus\Gsto1" "Hsap\GSTO1, Hsap\GSTO2" FBgn0037843 CG4511 - http://flybase.org/reports/FBgn0037843 protein_coding_gene queuine tRNA-ribosyltransferase activity ; GO:0008479 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000239043 queuosine biosynthetic process ; GO:0008616 | inferred from biological aspect of ancestor with PANTHER:PTN000239043 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000239043 CG4511 "IPR012336:Thioredoxin-like fold, IPR024253:Phosducin, thioredoxin-like domain" CG4511 11-Aug-17 DroID_v2017_08 "Drer\qtrtd1, Drer\txndc9" "Scer\PLP1, Scer\TRX3" "Cele\txdc-9, Cele\tgt-2" "Xtro\qtrtd1, Xtro\txndc9" "Mmus\Txndc9, Mmus\Qtrtd1" "Hsap\TXNDC9, Hsap\QTRT2" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0262514 VhaPPA1-2 Vacuolar H[+] ATPase PPA1 subunit 2 http://flybase.org/reports/FBgn0262514 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033176" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR002379 vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033176" "vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000001068 proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity with VhaPPA1-1 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from biological aspect of ancestor with PANTHER:PTN000029540" "vhaPPA1-2, CG7026, VhaPPA1-2" "IPR000245:V-ATPase proteolipid subunit, IPR002379:V-ATPase proteolipid subunit C-like domain" CG7026 11-Aug-17 DroID_v2017_08 Drer\atp6v0b Scer\VMA16 Cele\vha-4 Xtro\atp6v0b Mmus\Atp6v0b Hsap\ATP6V0B FBgn0032514 CG9302 - http://flybase.org/reports/FBgn0032514 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017937 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607" endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 "anon-WO0118547.80, CG9302" "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site" CG9302 11-Aug-17 DroID_v2017_08 "Drer\erp27, Drer\pdia5, Drer\pdia6, Drer\txndc16, Drer\dnajc10, Drer\txndc5" "Scer\EPS1, Scer\MPD2, Scer\MPD1" "Cele\dnj-27, Cele\Y49E10.4, Cele\D2092.4" "Xtro\txndc5, Xtro\pdia6, Xtro\txndc16" "Mmus\Txndc16, Mmus\Dnajc10, Mmus\Pdia6, Mmus\Erp27, Mmus\Pdia5, Mmus\Txndc5" "Hsap\PDIA5, Hsap\TXNDC5, Hsap\PDIA6, Hsap\PDILT, Hsap\TXNDC16, Hsap\DNAJC10, Hsap\ERP27" "lethal,partially lethal - majority die,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0032969 CG2528 - http://flybase.org/reports/FBgn0032969 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR002470, InterPro:IPR002471, InterPro:IPR023302 serine-type exopeptidase activity ; GO:0070008 | inferred from electronic annotation with InterPro:IPR023302" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001375, InterPro:IPR002470, InterPro:IPR002471" - "CG2528, lincRNA.224" "IPR002470:Peptidase S9A, prolyl oligopeptidase, IPR002471:Peptidase S9, serine active site, IPR029058:Alpha/Beta hydrolase fold, IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR023302:Peptidase S9A, N-terminal domain" CG2528 11-Aug-17 DroID_v2017_08 "Drer\prep, Drer\prepl" - - "Xtro\prep, Xtro\prepl" "Mmus\Prep, Mmus\Prepl" "Hsap\PREPL, Hsap\PREP" viable FBgn0261547 Exn Ephexin http://flybase.org/reports/FBgn0261547 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with RhoGEF4 "positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with RhoGEF4 imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from genetic interaction with GluRIIA, cac melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype" presynaptic membrane ; GO:0042734 | colocalizes_with inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay "Exn, CG3799, CG42665, CG14060, BcDNA:GH03693, exn" "IPR011993:PH domain-like, IPR000219:Dbl homology (DH) domain, IPR001452:SH3 domain" CG42665 11-Aug-17 DroID_v2017_08 "Drer\ngef, Drer\si:dkey-38p12.3, Drer\arhgef16, Drer\arhgef19, Drer\arhgef15, Drer\net1, Drer\arhgef3, Drer\arhgef5, Drer\si:ch73-15b2.5, Drer\arhgef3l" "Scer\TUS1, Scer\ROM1, Scer\ROM2" Cele\ephx-1 "Xtro\net1, Xtro\arhgef16, Xtro\arhgef26, Xtro\ngef" "Mmus\Ngef, Mmus\Net1, Mmus\Arhgef19, Mmus\Arhgef26, Mmus\Arhgef16, Mmus\Kalrn, Mmus\Arhgef5, Mmus\Arhgef3, Mmus\Arhgef15" "Hsap\ARHGEF16, Hsap\NGEF, Hsap\ARHGEF35, Hsap\NET1, Hsap\ARHGEF19, Hsap\ARHGEF26, Hsap\ARHGEF5, Hsap\KALRN, Hsap\ARHGEF3, Hsap\ARHGEF1, Hsap\ARHGEF15" FBgn0000228 Bsg25D Blastoderm-specific gene 25D http://flybase.org/reports/FBgn0000228 - protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay microtubule organizing center attachment site organization ; GO:0034994 | inferred from direct assay pericentriolar material ; GO:0000242 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "bsg25D, brg25D, bsq25D, CG14025, Bsg25D, nin, Nin" - CG14025 11-Aug-17 DroID_v2017_08 "Drer\nin, Drer\ninl" - Cele\T04F8.6 Xtro\nin "Mmus\Ninl, Mmus\Nin" "Hsap\NINL, Hsap\NIN" " embryonic stage | <=8 hr , embryonic stage | blastoderm " viable FBgn0259482 Mob3 MOB kinase activator 3 http://flybase.org/reports/FBgn0259482 protein_coding_gene "protein kinase binding ; GO:0019901 | inferred from sequence or structural similarity with mats, Mob4" - - "CG4946, dmob3, DMob3, Mob3, Dmob3" IPR005301:MOB kinase activator family CG4946 11-Aug-17 DroID_v2017_08 "Drer\mob1a, Drer\mob1bb, Drer\mob3a, Drer\mob1ba, Drer\mob3c" "Scer\MOB1, Scer\MOB2" "Cele\T12B3.4, Cele\F38H4.10" "Xtro\mob3c, Xtro\mob3b, Xtro\mob1b, Xtro\mob3a, Xtro\mob1a" "Mmus\Mob3a, Mmus\Mob3c, Mmus\Mob3b, Mmus\Mob1b, Mmus\Mob1a" "Hsap\MOB1A, Hsap\MOB1B, Hsap\MOB3B, Hsap\MOB3C, Hsap\MOB3A" FBgn0037328 RpL35A Ribosomal protein L35A http://flybase.org/reports/FBgn0037328 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001780, InterPro:IPR018266 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype" cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay "CG2099, L35a, anon-EST:Posey39, RpL35A, Rp L35A, Rpl35A" "IPR018266:Ribosomal protein L35Ae, conserved site, IPR001780:Ribosomal protein L35A, IPR009000:Translation protein, beta-barrel domain" CG2099 11-Aug-17 DroID_v2017_08 Drer\rpl35a "Scer\RPL33B, Scer\RPL33A" Cele\rpl-33 Xtro\rpl35a Mmus\Rpl35a Hsap\RPL35A lethal DRSC12302 IEK -1.614712965 -2.314268716 0.308625431 -5.26450209 1.467252014 3.8624467 FBgn0050431 CG30431 - http://flybase.org/reports/FBgn0050431 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG30431, CG8341, CG8324" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG30431 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-221f6.1, Drer\si:ch211-191d2.2, Drer\zgc:174928" Scer\ZAP1 "Cele\ces-1, Cele\Y111B2A.10, Cele\K11D2.4, Cele\eor-1, Cele\F58G1.2, Cele\unc-98" Xtro\znf329 - "Hsap\ZNF664, Hsap\ZNF25" FBgn0020767 Spred Sprouty-related protein with EVH-1 domain http://flybase.org/reports/FBgn0020767 FBgn0033964 protein_coding_gene - multicellular organism development ; GO:0007275 | inferred from electronic annotation with InterPro:IPR007875 regulation of signal transduction ; GO:0009966 | inferred from electronic annotation with InterPro:IPR007875 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR007875 cytosol ; GO:0005829 | inferred from direct assay "CG10155, AE33, Dm AE33, dSPRED, Spred, spred" "IPR000697:WH1/EVH1 domain, IPR007875:Sprouty, IPR011993:PH domain-like" CG10155 11-Aug-17 DroID_v2017_08 "Drer\spred3, Drer\spred2b, Drer\spred1, Drer\spred2a" - Cele\unc-34 "Xtro\spred2, Xtro\spred3, Xtro\spred1" "Mmus\Spred2, Mmus\Spred1, Mmus\Spred3" "Hsap\SPRED1, Hsap\SPRED3, Hsap\SPRED2" viable DRSC05976 I 1.537855042 1.289213427 1.019361063 0.0123239 -0.05308179 0.182783603 FBgn0262737 mub mushroom-body expressed http://flybase.org/reports/FBgn0262737 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 "thermosensory behavior ; GO:0040040 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0000381 "mub, MUB, Mub, CG7437, l(3)04093, l(3)j8B3, l(3)j6B10, anon-WO0172774.37, anon-WO0172774.36, anon-WO0172774.35, anon-WO0172774.33, MRE17" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG7437 11-Aug-17 DroID_v2017_08 "Drer\pcbp3, Drer\zgc:110045, Drer\hnrpkl, Drer\zgc:162999, Drer\pcbp2, Drer\hnrnpk, Drer\pcbp4" "Scer\HEK2, Scer\PBP2" "Cele\pes-4, Cele\hrpk-1" "Xtro\pcbp2, Xtro\pcbp3, Xtro\hnrnpk" "Mmus\Pcbp4, Mmus\Pcbp1, Mmus\Pcbp2, Mmus\Hnrnpk, Mmus\Pcbp3" "Hsap\PCBP3, Hsap\HNRNPK, Hsap\PCBP1, Hsap\PCBP4, Hsap\PCBP2" FBgn0261573 CoRest CoRest http://flybase.org/reports/FBgn0261573 protein_coding_gene "chromatin binding ; GO:0003682 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription corepressor activity ; GO:0003714 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 protein binding ; GO:0005515 | inferred from physical interaction with chn protein binding ; GO:0005515 | inferred from physical interaction with ttk transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN001043031" "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:17441 negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay positive regulation of methylation-dependent chromatin silencing ; GO:0090309 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype negative regulation of histone H4-K16 acetylation ; GO:2000619 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000412750 positive regulation of transcription of Notch receptor target ; GO:0007221 | inferred from mutant phenotype negative regulation of histone H3-K27 methylation ; GO:0061086 | inferred from mutant phenotype" transcriptional repressor complex ; GO:0017053 | inferred from physical interaction with HDAC1 inferred from physical interaction with Su(var)3-3 transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 nucleus ; GO:0005634 | inferred from direct assay "CoREST, CoRest, CG42687, CG3878, CG32535, i169, BcDNA:GH01486, BcDNA:LD11215, dCoREST, CG33525, CG32534, CoRESTG" "IPR017884:SANT domain, IPR000949:ELM2 domain, IPR001005:SANT/Myb domain, IPR009057:Homeobox domain-like" CG42687 11-Aug-17 DroID_v2017_08 "Drer\rcor2, Drer\rcor1, Drer\elmsan1a, Drer\rcor3" Scer\SNT1 "Cele\spr-1, Cele\rcor-1" "Xtro\rcor2, Xtro\rcor3, Xtro\rcor1" "Mmus\Elmsan1, Mmus\Rcor2, Mmus\Rcor3, Mmus\Rcor1" "Hsap\RCOR1, Hsap\NCOR1, Hsap\RCOR2, Hsap\RCOR3" DRSC22305 IEK 2.819467377 -3.133707857 1.301265246 -1.975353383 1.518618668 0.882145134 FBgn0001285 Jon44E Jonah 44E http://flybase.org/reports/FBgn0001285 FBgn0033319 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG8579, SP100, Jon43E, Jon44E" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG8579 11-Aug-17 DroID_v2017_08 "Drer\zgc:92041, Drer\masp2, Drer\zgc:163025, Drer\zgc:92745, Drer\zgc:112368, Drer\zgc:112302, Drer\zgc:112285, Drer\ela3l" - Cele\svh-1 - "Mmus\C1s1, Mmus\C1s2, Mmus\Ctrc, Mmus\Cela3b, Mmus\Ctrb1, Mmus\F9, Mmus\Cela2a, Mmus\Cela1, Mmus\Cela3a, Mmus\Ctrl" "Hsap\PROC, Hsap\C1S" viable FBgn0033350 CG8237 - http://flybase.org/reports/FBgn0033350 protein_coding_gene - - - CG8237 IPR010432:RDD CG8237 11-Aug-17 DroID_v2017_08 "Drer\fam8a1b, Drer\fam8a1a" - Cele\F48B9.8 Xtro\fam8a1 Mmus\Fam8a1 Hsap\FAM8A1 viable FBgn0039994 conu conundrum http://flybase.org/reports/FBgn0039994 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Moe "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 positive regulation of cell proliferation ; GO:0008284 | inferred from genetic interaction with Moe positive regulation of GTPase activity ; GO:0043547 | inferred from genetic interaction with Rac1 negative regulation of GTPase activity ; GO:0034260 | inferred from genetic interaction with Rho1" apical cortex ; GO:0045179 | inferred from direct assay "CG40286, BcDNA:LD04957, conu, CG17082" "IPR000198:Rho GTPase-activating protein domain, IPR008936:Rho GTPase activation protein" CG17082 11-Aug-17 DroID_v2017_08 "Drer\arhgap28, Drer\stard8, Drer\stard13a, Drer\dlc1, Drer\arhgap32b, Drer\si:dkeyp-23e4.3, Drer\stard13b, Drer\arhgap18" "Scer\RGD1, Scer\BEM3, Scer\LRG1" "Cele\gei-1, Cele\2RSSE.1" "Xtro\stard13, Xtro\arhgap28, Xtro\stard8, Xtro\dlc1, Xtro\arhgap18, Xtro\arhgap40" "Mmus\Arhgap28, Mmus\Dlc1, Mmus\Arhgap40, Mmus\Arhgap18, Mmus\Stard13, Mmus\Stard8" "Hsap\ARHGAP28, Hsap\ARHGAP18, Hsap\STARD13, Hsap\ARHGAP40, Hsap\DLC1, Hsap\STARD8" "viable,fertile,cell shape defective,neoplasia,increased cell size" "wing disc,eye" FBgn0034817 Art7 Arginine methyltransferase 7 http://flybase.org/reports/FBgn0034817 protein_coding_gene protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243 | inferred from mutant phenotype protein-arginine N-methyltransferase activity ; GO:0016274 | inferred from sequence or structural similarity with Art1 "peptidyl-arginine methylation, to asymmetrical-dimethyl arginine ; GO:0019919 | inferred from sequence or structural similarity with Art1 peptidyl-arginine methylation ; GO:0018216 | inferred from mutant phenotype" - "DART7, CG9882, Art7, dart7" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR014644:Protein arginine N-methyltransferase PRMT7, IPR025799:Protein arginine N-methyltransferase" CG9882 11-Aug-17 DroID_v2017_08 Drer\prmt7 - "Cele\prmt-3, Cele\prmt-7" Xtro\prmt7 Mmus\Prmt7 Hsap\PRMT7 "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0036492 Best3 Bestrophin 3 http://flybase.org/reports/FBgn0036492 protein_coding_gene chloride channel activity ; GO:0005254 | inferred from sequence or structural similarity with Best1 chloride transport ; GO:0006821 | inferred from sequence or structural similarity with Best1 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Best1 "dbest3, CG12327, Best3, dBest3" "IPR000615:Bestrophin, IPR021134:Bestrophin/UPF0187" CG12327 11-Aug-17 DroID_v2017_08 "Drer\best1, Drer\best4, Drer\best2" - "Cele\sma-10, Cele\best-25, Cele\best-18, Cele\best-26, Cele\best-2, Cele\best-17, Cele\best-11, Cele\best-10, Cele\best-1, Cele\best-12, Cele\best-21, Cele\best-6, Cele\best-8, Cele\best-23, Cele\best-22, Cele\best-3, Cele\best-9, Cele\best-20, Cele\best-13, Cele\best-15, Cele\best-7, Cele\best-4, Cele\C09B9.85, Cele\best-16, Cele\best-5, Cele\best-24, Cele\best-19, Cele\best-14" "Xtro\best4, Xtro\best2, Xtro\best1, Xtro\best3" "Mmus\Best3, Mmus\Best2, Mmus\Best1" "Hsap\BEST4, Hsap\BEST1, Hsap\BEST3, Hsap\BEST2" viable FBgn0032209 Hand Hand http://flybase.org/reports/FBgn0032209 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with twi transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" "hemopoiesis ; GO:0030097 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with twi positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay larval heart development ; GO:0007508 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0003700 "hand, Dhand, dHand, dHAND, CG18144, Hand, HAND, bHLHa28, hand-C" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG18144 11-Aug-17 DroID_v2017_08 "Drer\tcf23, Drer\msgn1, Drer\twist1a, Drer\ptf1a, Drer\tal1, Drer\twist3, Drer\twist1b, Drer\tcf15, Drer\mespaa, Drer\si:ch211-246m6.4, Drer\nhlh2, Drer\ascl1a, Drer\mespba, Drer\tal2, Drer\ascl1b, Drer\scxb, Drer\figla, Drer\tcf21, Drer\mespab, Drer\scxa, Drer\twist2, Drer\msc, Drer\tcf24, Drer\lyl1, Drer\hand2" - "Cele\hlh-16, Cele\hlh-31, Cele\hnd-1, Cele\hlh-8, Cele\hlh-32, Cele\hlh-17" "Xtro\msgn1, Xtro\figla, Xtro\mespa, Xtro\tcf21, Xtro\ascl2, Xtro\mespb, Xtro\ptf1a, Xtro\tal1, Xtro\msc, Xtro\tcf15, Xtro\scx, Xtro\nhlh1, Xtro\lyl1, Xtro\hand2, Xtro\ascl3, Xtro\hand1" "Mmus\Nhlh2, Mmus\Ascl5, Mmus\Tcf23, Mmus\Lyl1, Mmus\Hand2, Mmus\Ferd3l, Mmus\Tcf15, Mmus\Hand1, Mmus\Tal1, Mmus\Figla, Mmus\Mesp2, Mmus\Twist1, Mmus\Msc, Mmus\Ascl4, Mmus\Scx, Mmus\Tal2, Mmus\Msgn1, Mmus\Twist2, Mmus\Ptf1a, Mmus\Mesp1, Mmus\Nhlh1, Mmus\Ascl3, Mmus\Ascl1, Mmus\Tcf21" "Hsap\TCF21, Hsap\HAND1, Hsap\ASCL5, Hsap\NHLH2, Hsap\FIGLA, Hsap\TWIST2, Hsap\ASCL1, Hsap\TCF23, Hsap\TAL1, Hsap\NHLH1, Hsap\LYL1, Hsap\PTF1A, Hsap\TCF15, Hsap\TWIST1, Hsap\MESP1, Hsap\HAND2, Hsap\MESP2, Hsap\TAL2, Hsap\TCF24, Hsap\ASCL3, Hsap\MSGN1, Hsap\ASCL4, Hsap\SCX, Hsap\MSC" "neuroanatomy defective,lethal - all die before end of larval stage,some die during third instar larval stage,lethal,small body,locomotor rhythm defective,increased cell death,partially lethal - majority die,recessive,fertile,short lived,some die during first instar larval stage,flight defective,locomotor behavior defective,some die during immature adult stage,viable" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,cardioblast,embryonic pericardial cell,lymph gland primordium,alary cell,lymph gland derived hemocyte,embryonic/larval heart,embryonic/larval pericardial cell,embryonic/larval lymph gland,adult peritrophic membrane,adult dorsal vessel,adult midgut,crop" FBgn0001206 Hmr Hybrid male rescue http://flybase.org/reports/FBgn0001206 FBgn0027511 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Lhr mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from mutant phenotype regulation of transposition ; GO:0010528 | inferred from mutant phenotype "chromosome, centromeric region ; GO:0000775 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay" "CG1619, BcDNA:LD22117, hmr, Hmr, Hmr-mel, Hmr[[mel]], HMR" "IPR016641:Nascent polypeptide-associated complex subunit alpha, IPR006578:MADF domain" CG1619 11-Aug-17 DroID_v2017_08 "Drer\naca, Drer\nacad" Scer\EGD2 Cele\icd-2 - "Mmus\Nacad, Mmus\Naca" "Hsap\NACA, Hsap\NACA2, Hsap\MDC1, Hsap\NACAD" "female sterile,partially,recessive" "egg,ovariole,egg chamber,dorsal appendage" FBgn0032896 CG14400 - http://flybase.org/reports/FBgn0032896 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14400 - CG14400 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC02384 I 2.401640782 0.15045359 0.312504301 0.331317489 -0.138508357 0.53846124 FBgn0022039 l(2)k08407 lethal (2) k08407 http://flybase.org/reports/FBgn0022039 - gene - - - l(2)k08407 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,wing vein" FBgn0002422 l(3)F13 lethal (3) F13 http://flybase.org/reports/FBgn0002422 - gene - - - "l(3)13, l(3)F13" - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0034131 CG15712 - http://flybase.org/reports/FBgn0034131 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15712 IPR010629:Insect allergen-related CG15712 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0032262 CG7384 - http://flybase.org/reports/FBgn0032262 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from biological aspect of ancestor with PANTHER:PTN001076968 - CG7384 "IPR005240:Protein of unknown function DUF389, IPR020846:Major facilitator superfamily domain" CG7384 11-Aug-17 DroID_v2017_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053051 CG33051 - http://flybase.org/reports/FBgn0053051 protein_coding_gene - transcription from RNA polymerase III promoter ; GO:0006383 | inferred from electronic annotation with InterPro:IPR024661 neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN001034674 nuclear chromatin ; GO:0000790 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001034674 "CG3882, CG33051" "IPR024661:DNA-directed RNA polymerase III, subunit Rpc31" CG33051 11-Aug-17 DroID_v2017_08 "Drer\polr3g, Drer\polr3glb, Drer\polr3gla" - Cele\Y47G6A.9 Xtro\polr3gl "Mmus\Polr3gl, Mmus\Polr3g" "Hsap\POLR3G, Hsap\POLR3GL" "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0039858 CycG Cyclin G http://flybase.org/reports/FBgn0039858 protein_coding_gene cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from sequence or structural similarity meiotic DNA repair synthesis ; GO:0000711 | inferred from mutant phenotype positive regulation of growth ; GO:0045927 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from genetic interaction with Abd-B female meiotic division ; GO:0007143 | inferred from mutant phenotype negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from genetic interaction with CycE double-strand break repair ; GO:0006302 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with H inferred from genetic interaction with N polytene chromosome ; GO:0005700 | inferred from direct assay "CG11525, i205, i261, dCycG, CG 11525, clone 2.24, clone 1.25, anon-EST:Liang-2.24, anon-EST:Liang-1.25, CycG, cycG, chr3R:27424276..27424475" "IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like" CG11525 11-Aug-17 DroID_v2017_08 "Drer\ccni, Drer\ccng2, Drer\ccnb3, Drer\ccni2, Drer\ccnb2, Drer\si:ch211-132b12.8, Drer\ccnb1, Drer\ccng1, Drer\ccnb1l" "Scer\CLN1, Scer\CLB6, Scer\CLB1, Scer\CLB3, Scer\CLN3, Scer\CLN2, Scer\CLB2, Scer\CLB4, Scer\CLB5" - "Xtro\ccni2, Xtro\LOC100487861, Xtro\ccnb1.2, Xtro\ccnb3, Xtro\ccni, Xtro\ccnb1, Xtro\ccno, Xtro\ccnb2, Xtro\ccng2, Xtro\ccng1" "Mmus\Ccnb2, Mmus\Ccnb3, Mmus\Ccno, Mmus\Ccni, Mmus\Ccng1, Mmus\Ccng2, Mmus\Ccnb1" "Hsap\CCNB2, Hsap\CCNG1, Hsap\CCNB3, Hsap\CCNI2, Hsap\CCNB1, Hsap\CCNI, Hsap\CCNG2, Hsap\CNTD2, Hsap\CCNO" "lethal,developmental rate defective,increased cell size,partially lethal - majority die,male limited,partially lethal - majority live,female limited,viable,decreased cell size,mitotic cell cycle defective,somatic clone,female sterile,fertile" "wing,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,male genitalia,female limited,ommatidium,anterior dorsal histoblast nest abdominal 4,posterior dorsal histoblast nest abdominal 4,anterior dorsal histoblast nest abdominal 5,posterior dorsal histoblast nest abdominal 5,anterior dorsal histoblast nest abdominal 6,posterior dorsal histoblast nest abdominal 6,wing disc,posterior compartment,somatic clone,dorsal appendage,maternal effect,germline clone,karyosome" DRSC14324 I 0.852304076 -1.525231705 -0.742036846 -0.187639725 0.278644861 -0.639233176 FBgn0028703 Nhe3 Na[+]/H[+] hydrogen exchanger 3 http://flybase.org/reports/FBgn0028703 protein_coding_gene sodium:proton antiporter activity ; GO:0015385 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 potassium:proton antiporter activity ; GO:0015386 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 sodium ion import across plasma membrane ; GO:0098719 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 potassium ion transmembrane transport ; GO:0071805 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002090, InterPro:IPR004709, InterPro:IPR006153, InterPro:IPR018422 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from biological aspect of ancestor with PANTHER:PTN000803768" "NHE3, DmNHE3, CG11328, Nhe3, nhe3" "IPR018422:Cation/H+ exchanger, CPA1 family, IPR002090:Na+/H+ exchanger, isoform 6 (NHE6), IPR004709:Na+/H+ exchanger, IPR006153:Cation/H+ exchanger" CG11328 11-Aug-17 DroID_v2017_08 "Drer\slc9a7, Drer\slc9a8, Drer\slc9a6a, Drer\slc9a6b" Scer\NHX1 "Cele\nhx-8, Cele\pbo-4, Cele\nhx-5" "Xtro\slc9a6, Xtro\slc9a8, Xtro\slc9a7, Xtro\slc9a9" "Mmus\Slc9c1, Mmus\Slc9a6, Mmus\Slc9a9, Mmus\Slc9a8, Mmus\Slc9a7" "Hsap\SLC9A6, Hsap\SLC9C1, Hsap\SLC9A8, Hsap\SLC9A7, Hsap\SLC9A9" viable FBgn0039307 CR13656 - http://flybase.org/reports/FBgn0039307 pseudogene_attribute - - - "CG13656, CR13656" - CR13656 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0036199 Bmcp Bmcp http://flybase.org/reports/FBgn0036199 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with UniProtKB:O95258 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 regulation of metabolic process ; GO:0019222 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:O95258 "dmUCP5, DmUCP5, DmBMCP, CG7314, Bmcp, UCP5, ucp5, Ucp5, bmcp, BMCP, dmUcp5" "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG7314 11-Aug-17 DroID_v2017_08 "Drer\slc25a11, Drer\slc25a35, Drer\si:ch1073-100f3.2, Drer\ucp1, Drer\slc25a27, Drer\ucp2, Drer\ucp3, Drer\mrpl12, Drer\slc25a14, Drer\slc25a34, Drer\slc25a10" "Scer\DIC1, Scer\OAC1" "Cele\mrpl-12, Cele\misc-1, Cele\ucp-4, Cele\slc-25A10" "Xtro\ucp1, Xtro\slc25a10, Xtro\slc25a27, Xtro\rangrf, Xtro\ucp2, Xtro\slc25a30" "Mmus\Ucp1, Mmus\Ucp2, Mmus\Mrpl12, Mmus\Slc25a27, Mmus\Slc25a35, Mmus\Slc25a14, Mmus\Ucp3, Mmus\Slc25a30, Mmus\Slc25a10, Mmus\Slc25a34, Mmus\Slc25a11" "Hsap\UCP3, Hsap\SLC25A35, Hsap\UCP2, Hsap\SLC25A10, Hsap\MRPL12, Hsap\UCP1, Hsap\SLC25A11, Hsap\SLC25A14, Hsap\SLC25A34, Hsap\SLC25A30, Hsap\SLC25A27" "stress response defective,viable,auditory perception defective,neurophysiology defective" FBgn0024947 NTPase NTPase http://flybase.org/reports/FBgn0024947 - protein_coding_gene uridine-diphosphatase activity ; GO:0045134 | inferred from direct assay guanosine-diphosphatase activity ; GO:0004382 | inferred from direct assay - cytoplasm ; GO:0005737 | inferred from direct assay "NTPase, dmNTPase, CG3059, NTPDase6" IPR000407:Nucleoside phosphatase GDA1/CD39 CG3059 11-Aug-17 DroID_v2017_08 "Drer\entpd5a, Drer\entpd6, Drer\entpd5b, Drer\entpd4" "Scer\YND1, Scer\GDA1" "Cele\ntp-1, Cele\mig-23, Cele\uda-1" "Xtro\entpd4, Xtro\entpd7, Xtro\entpd6, Xtro\entpd5" "Mmus\Entpd7, Mmus\Entpd6, Mmus\Gm21685, Mmus\Entpd5, Mmus\Entpd4" "Hsap\ENTPD4, Hsap\ENTPD5, Hsap\ENTPD7, Hsap\ENTPD6" viable DRSC26233 K 0.045008898 -0.514548332 0.419207756 -0.249423221 -1.292641967 -1.583626239 FBgn0020909 Rtc1 Rtc1 http://flybase.org/reports/FBgn0020909 - protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR013792 ribosome biogenesis ; GO:0042254 | inferred from electronic annotation with InterPro:IPR016443 RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR000228 cellular response to starvation ; GO:0009267 | inferred from expression pattern nucleolus ; GO:0005730 | inferred from electronic annotation with InterPro:IPR016443 "CG11130, Rtc1" "IPR000228:RNA 3'-terminal phosphate cyclase, IPR013792:RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta, IPR016443:RNA 3'-terminal phosphate cyclase type 2, IPR020719:RNA 3'-terminal phosphate cyclase-like, conserved site, IPR013791:RNA 3'-terminal phosphate cyclase, insert domain, IPR023797:RNA 3'-terminal phosphate cyclase domain" CG11130 11-Aug-17 DroID_v2017_08 "Drer\rcl1, Drer\rtca" Scer\RCL1 Cele\ZK1127.5 Xtro\rcl1 "Mmus\Rcl1, Mmus\Rtca" "Hsap\RTCA, Hsap\RCL1" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC20285 E -1.011133935 -0.196341902 2.129391108 0.702359788 0.930255036 0.315352417 FBgn0283479 Alp1 Alkaline phosphatase 1 http://flybase.org/reports/FBgn0283479 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from direct assay alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 "CG5656, Alp1, APH, Aph, p-Aph, l-Aph, Aph-1" "IPR001952:Alkaline phosphatase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG5656 11-Aug-17 DroID_v2017_08 "Drer\alpl, Drer\alp3, Drer\alpi.2, Drer\alpi.1" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1, Xtro\alpi.2" "Mmus\Alpi, Mmus\Alpl, Mmus\Alppl2, Mmus\Akp3" "Hsap\ALPP, Hsap\ALPI, Hsap\ALPPL2, Hsap\ALPL" FBgn0026148 CG12253 - http://flybase.org/reports/FBgn0026148 FBgn0032326 protein_coding_gene - - - "LD08487, BEST:LD08487, CG12253, DPLG1" IPR027806:Harbinger transposase-derived nuclease domain CG12253 11-Aug-17 DroID_v2017_08 "Drer\zgc:194221, Drer\si:ch73-257c13.2, Drer\si:dkey-197c15.6, Drer\zgc:162945, Drer\harbi1, Drer\LOC569097, Drer\LOC100005423, Drer\zmp:0000000634, Drer\zgc:113227" - - "Xtro\harbi1, Xtro\LOC100127800, Xtro\LOC100135188" Mmus\Harbi1 Hsap\HARBI1 viable FBgn0034057 CG8314 - http://flybase.org/reports/FBgn0034057 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 Golgi apparatus ; GO:0005794 | inferred from direct assay "anon-WO0118547.93, CG8314" "IPR001594:Palmitoyltransferase, DHHC domain" CG8314 11-Aug-17 DroID_v2017_08 "Drer\zdhhc22, Drer\zdhhc9, Drer\LOC100334198, Drer\zdhhc1, Drer\zdhhc12b, Drer\zdhhc5b, Drer\zdhhc12a, Drer\zdhhc18a, Drer\zdhhc5a, Drer\zdhhc21, Drer\zdhhc14, Drer\zdhhc7, Drer\zdhhc23b, Drer\zdhhc3b, Drer\zdhhc8b, Drer\zgc:77880, Drer\zdhhc24, Drer\zdhhc23a, Drer\zdhhc3a" "Scer\PFA5, Scer\SWF1, Scer\PFA3, Scer\ERF2" Cele\dhhc-3 "Xtro\zdhhc14, Xtro\zdhhc7, Xtro\dnz1, Xtro\zdhhc8, Xtro\zdhhc24, Xtro\zdhhc3, Xtro\zdhhc1, Xtro\zdhhc12, Xtro\zdhhc9, Xtro\zdhhc21" "Mmus\Zdhhc24, Mmus\Zdhhc18, Mmus\Zdhhc12, Mmus\Zdhhc14, Mmus\Zdhhc3, Mmus\Zdhhc23, Mmus\Zdhhc5, Mmus\Zdhhc7, Mmus\Zdhhc25, Mmus\Zdhhc1, Mmus\Zdhhc8, Mmus\Zdhhc19, Mmus\Zdhhc11, Mmus\Zdhhc22, Mmus\Zdhhc21, Mmus\Zdhhc9" "Hsap\ZDHHC22, Hsap\ZDHHC21, Hsap\ZDHHC23, Hsap\ZDHHC19, Hsap\ZDHHC14, Hsap\ZDHHC9, Hsap\ZDHHC5, Hsap\ZDHHC11, Hsap\ZDHHC7, Hsap\ZDHHC12, Hsap\ZDHHC8, Hsap\ZDHHC1, Hsap\ZDHHC18, Hsap\ZDHHC24, Hsap\ZDHHC3" viable FBgn0024957 Irp-1B Iron regulatory protein 1B http://flybase.org/reports/FBgn0024957 - protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR029784 aconitate hydratase activity ; GO:0003994 | inferred from direct assay iron-responsive element binding ; GO:0030350 | NOT inferred from direct assay" "response to iron(II) ion ; GO:0010040 | inferred from electronic annotation with InterPro:IPR029784 cellular iron ion homeostasis ; GO:0006879 | inferred from electronic annotation with InterPro:IPR029784 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000573, InterPro:IPR001030, InterPro:IPR015931, InterPro:IPR015932, InterPro:IPR015937" - "144037_at, IRP-1B, IRP1, IRP-1, CG6342, Irp-1B, irp-1B, C-Acon, cAcon, irp1B, cACON, dIRP, IRP, IRF" "IPR015928:Aconitase/3-isopropylmalate dehydratase, swivel, IPR015931:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3, IPR015932:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2, IPR018136:Aconitase family, 4Fe-4S cluster binding site, IPR000573:Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, IPR001030:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain, IPR006249:Aconitase/Iron-responsive element-binding protein 2, IPR029784:Iron regulatory protein 1" CG6342 11-Aug-17 DroID_v2017_08 "Drer\aco1, Drer\aco2, Drer\ireb2" "Scer\ACO1, Scer\ACO2" "Cele\aco-2, Cele\aco-1" "Xtro\aco1, Xtro\ireb2" "Mmus\Aco1, Mmus\Ireb2, Mmus\Aco2" "Hsap\ACO2, Hsap\ACO1, Hsap\IREB2" embryonic stage

ubiquitous viable DRSC16720 K 0.090566824 0.300317442 -0.153741897 1.119953391 -0.286727145 -1.604563446 FBgn0030766 mthl1 methuselah-like 1 http://flybase.org/reports/FBgn0030766 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor activity ; GO:0004930 | inferred from physical interaction with fog cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity gastrulation ; GO:0007369 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth mesectoderm development ; GO:0048383 | inferred from mutant phenotype actin-mediated cell contraction ; GO:0070252 | inferred from genetic interaction with fog regulation of myosin II filament organization ; GO:0043519 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with fog response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype inferred from genetic interaction with fog mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "Mth-1, CG4521, anon-WO0170980.23, anon-WO0170980.22, mthl1, mist, Mist" "IPR017981:GPCR, family 2-like, IPR000832:GPCR, family 2, secretin-like, IPR023311:Methuselah ectodomain, domain 2" CG4521 11-Aug-17 DroID_v2017_08 "Drer\adgrg11, Drer\adgrd2, Drer\adgrg3, Drer\fbn2b, Drer\adgrl4, Drer\adgrg4a, Drer\adgre10, Drer\adgrl3.1, Drer\fbn2a, Drer\LOC101886975, Drer\adgrf3a, Drer\adgrl2a, Drer\adgrg2a, Drer\adgrf6, Drer\LOC100535070, Drer\adgrg1, Drer\adgrg6, Drer\adgrl1a, Drer\adgre14, Drer\adgre5b.3, Drer\LOC100538279, Drer\adgrf11, Drer\LOC100537181, Drer\LOC101884341" - Cele\lat-2 "Xtro\adgrf1, Xtro\adgrf3, Xtro\adgrd1, Xtro\adgrv1, Xtro\adgrg1, Xtro\adgre5, Xtro\adgrl1" "Mmus\Adgrf3, Mmus\Adgrg7, Mmus\Adgrf4, Mmus\Adgrg5, Mmus\Adgrg6, Mmus\Adgrg4, Mmus\Adgrl3, Mmus\Adgre1, Mmus\Adgrf5, Mmus\Adgrd1, Mmus\Adgrf2, Mmus\Adgrg3, Mmus\Adgrg2, Mmus\Adgrl2, Mmus\Adgre4, Mmus\Adgrg1, Mmus\Adgrl1, Mmus\Adgrf1, Mmus\Adgrl4, Mmus\Adgre5" "Hsap\ADGRG4, Hsap\ADGRG5, Hsap\ADGRE1, Hsap\ADGRE5, Hsap\ADGRG2, Hsap\ADGRF4, Hsap\ADGRF5, Hsap\ADGRG6, Hsap\ADGRG1, Hsap\ADGRD2, Hsap\ADGRG7, Hsap\ADGRL4, Hsap\ADGRF2, Hsap\ADGRE2, Hsap\ADGRF1, Hsap\ADGRG3, Hsap\ADGRL1, Hsap\ADGRE3, Hsap\FBN3, Hsap\ADGRD1, Hsap\ADGRL2, Hsap\ADGRF3, Hsap\ADGRL3" "viable,fertile" wing disc FBgn0035772 Sh3beta Sh3beta http://flybase.org/reports/FBgn0035772 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001744534 "LD12912, CG8582, Sh3beta, SH3beta" "IPR006993:SH3-binding, glutamic acid-rich protein, IPR012336:Thioredoxin-like fold" CG8582 11-Aug-17 DroID_v2017_08 "Drer\sh3bgrl2, Drer\sh3bgr, Drer\zgc:153284, Drer\sh3bgrl3, Drer\sh3bgrl" "Scer\MIA40, Scer\YFR016C" Cele\Y105E8A.1 "Xtro\sh3bgrl2, Xtro\sh3bgrl3, Xtro\sh3bgr" "Mmus\Sh3bgr, Mmus\Sh3bgrl, Mmus\Hmgn5, Mmus\Sh3bgrl2, Mmus\Sh3bgrl3" "Hsap\SH3BGRL3, Hsap\SH3BGR, Hsap\SH3BGRL2, Hsap\SH3BGRL" "lethal,viable" adult heart FBgn0038302 CG4210 - http://flybase.org/reports/FBgn0038302 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001632117 - - "BcDNA:SD26038, BcDNA:SD13446, CG4210, FBgn 38302" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG4210 11-Aug-17 DroID_v2017_08 "Drer\pimr131, Drer\sat1b, Drer\si:dkey-19b23.15, Drer\zp2.6, Drer\sat2a, Drer\si:zfos-1505d6.3, Drer\zp2l1, Drer\zp2.5, Drer\sat1a.2, Drer\sat1a.1, Drer\LOC101883245, Drer\sat2b" "Scer\HPA2, Scer\HPA3" "Cele\mltn-9, Cele\H37A05.4, Cele\D2023.4, Cele\VH15N14R.1, Cele\mltn-10, Cele\Y9D1A.2, Cele\Y39B6A.9, Cele\F20B6.7, Cele\mltn-12" "Xtro\sat1, Xtro\sat2, Xtro\zp4.2, Xtro\zp4" "Mmus\Sat2, Mmus\Satl1, Mmus\Zp1, Mmus\Sat1, Mmus\LOC102639543" "Hsap\ZP4, Hsap\ZP1, Hsap\SAT2, Hsap\SATL1, Hsap\SAT1" viable FBgn0034176 ste24a prenyl protease type I http://flybase.org/reports/FBgn0034176 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000012712 CAAX-box protein processing ; GO:0071586 | inferred from biological aspect of ancestor with PANTHER:PTN000012712 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000012714 "CG9000, ste24a, Dmel\Ste24, Dmel\Ste24a" "IPR001915:Peptidase M48, IPR027057:CAAX prenyl protease 1, IPR032456:CAAX prenyl protease 1, N-terminal" CG9000 11-Aug-17 DroID_v2017_08 Drer\zmpste24 Scer\STE24 Cele\fce-1 Xtro\zmpste24 Mmus\Zmpste24 Hsap\ZMPSTE24 "viable,fertile" DRSC26491 K 0.737591429 0.607772447 0.375596872 -0.035028988 0.107675358 1.882966932 FBgn0026361 Sep5 Septin 5 http://flybase.org/reports/FBgn0026361 FBgn0033242 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR016491, InterPro:IPR030379 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with pnut" regulation of cell cycle ; GO:0051726 | inferred from genetic interaction with Sep2 mitotic cytokinesis ; GO:0000281 | inferred from sequence or structural similarity imaginal disc development ; GO:0007444 | inferred from genetic interaction with Sep2 septin ring ; GO:0005940 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay "CG2916, Sep, sep5, Sep5, dSEPT5" "IPR030379:Septin-type guanine nucleotide-binding (G) domain, IPR016491:Septin, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2916 11-Aug-17 DroID_v2017_08 "Drer\sept8a, Drer\sept7b, Drer\sept8b, Drer\sept5a, Drer\zgc:63587, Drer\zgc:162239, Drer\sept7a, Drer\sept2, Drer\sept4b, Drer\sept6, Drer\sept4a, Drer\sept10, Drer\sept5b, Drer\sept15" "Scer\CDC11, Scer\SPR3, Scer\CDC12, Scer\SPR28, Scer\CDC3, Scer\SHS1" Cele\unc-61 "Xtro\sept7, Xtro\sept6, Xtro\sept2, Xtro\sept11, Xtro\sept8, Xtro\sept10" "Mmus\Sept8, Mmus\Sept11, Mmus\Sept2, Mmus\Sept5, Mmus\Sept7, Mmus\Sept4, Mmus\Sept6, Mmus\Sept10, Mmus\Sept1, Mmus\Sept14" "Hsap\SEPT7, Hsap\SEPT11, Hsap\SEPT14, Hsap\SEPT5, Hsap\SEPT2, Hsap\C9orf69, Hsap\SEPT8, Hsap\SEPT4, Hsap\SEPT10, Hsap\SEPT6" "viable,fertile" DRSC29954 K 0.359303028 0.312490591 -0.024393112 0.274095324 -0.033047005 1.551718985 FBgn0004463 RpIII128 RNA polymerase III 128kD subunit http://flybase.org/reports/FBgn0004463 "FBtr0087977, FBpp0087085" protein_coding_gene "ribonucleoside binding ; GO:0032549 | inferred from electronic annotation with InterPro:IPR015712 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007120, InterPro:IPR007121, InterPro:IPR007641, InterPro:IPR007642, InterPro:IPR007644, InterPro:IPR007645, InterPro:IPR007646 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000465879" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR007120, InterPro:IPR007121, InterPro:IPR007641, InterPro:IPR007642, InterPro:IPR007644, InterPro:IPR007645, InterPro:IPR007646, InterPro:IPR007647, InterPro:IPR015712" DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000465879 "RpIII128, DmRP128, RP128, CG8344" "IPR015712:DNA-directed RNA polymerase, subunit 2, IPR007120:DNA-directed RNA polymerase, subunit 2, domain 6, IPR007121:RNA polymerase, beta subunit, conserved site, IPR007641:RNA polymerase Rpb2, domain 7, IPR007642:RNA polymerase Rpb2, domain 2, IPR007644:RNA polymerase, beta subunit, protrusion, IPR007645:RNA polymerase Rpb2, domain 3, IPR007646:RNA polymerase Rpb2, domain 4, IPR007647:RNA polymerase Rpb2, domain 5" CG8344 11-Aug-17 DroID_v2017_08 Drer\polr3b "Scer\RET1, Scer\RPB2" "Cele\rpc-2, Cele\rpb-2" Xtro\polr3b "Mmus\Polr2b, Mmus\Polr3b" "Hsap\POLR3B, Hsap\POLR2B" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0259145 CG42260 - http://flybase.org/reports/FBgn0259145 protein_coding_gene intracellular cyclic nucleotide activated cation channel activity ; GO:0005221 | inferred from sequence or structural similarity with CngA voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 cyclic-nucleotide-mediated signaling ; GO:0019935 | inferred from sequence or structural similarity with CngA regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 cation transport ; GO:0006812 | inferred from sequence or structural similarity with CngA integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 intracellular cyclic nucleotide activated cation channel complex ; GO:0017071 | inferred from sequence or structural similarity with CngA "CG42260, CG13530, CG3536, lincRNA.378, dmCNG4" "IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR014710:RmlC-like jelly roll fold, IPR005821:Ion transport domain" CG42260 11-Aug-17 DroID_v2017_08 "Drer\cnga3a, Drer\hcn4l, Drer\cnga1, Drer\cnga4, Drer\LOC100334711, Drer\si:dkey-22i16.2, Drer\cngb3.1, Drer\LOC100334297, Drer\cnga5, Drer\cngb1a, Drer\LOC103911065, Drer\hcn3" - "Cele\che-6, Cele\cng-1, Cele\cng-3, Cele\cng-2, Cele\tax-4, Cele\tax-2" "Xtro\cnga4, Xtro\cnga1, Xtro\cngb3, Xtro\cngb1, Xtro\cnga3" "Mmus\Hcn4, Mmus\Cnga2, Mmus\Hcn2, Mmus\Cnga1, Mmus\Hcn3, Mmus\Cngb1, Mmus\Hcn1, Mmus\Cnga3, Mmus\Cngb3, Mmus\Cnga4" "Hsap\CNGA1, Hsap\CNGB3, Hsap\CNGB1, Hsap\CNGA4, Hsap\CNGA3, Hsap\CNGA2" FBgn0000116 Argk Arginine kinase http://flybase.org/reports/FBgn0000116 "FBgn0035958, FBgn0052031" protein_coding_gene arginine kinase activity ; GO:0004054 | inferred from sequence or structural similarity with UniProtKB:P51541 phosphorylation ; GO:0016310 | inferred from sequence or structural similarity with UniProtKB:P51541 extracellular region ; GO:0005576 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "ArgK, CG32031, CG4929, argk, CG5173, AK, argK, AK-1, ARK, Argk" "IPR014746:Glutamine synthetase/guanido kinase, catalytic domain, IPR000749:ATP:guanido phosphotransferase, IPR022413:ATP:guanido phosphotransferase, N-terminal, IPR022414:ATP:guanido phosphotransferase, catalytic domain, IPR022415:ATP:guanido phosphotransferase active site" CG32031 11-Aug-17 DroID_v2017_08 "Drer\ckmt1, Drer\ckbb, Drer\pgm5, Drer\ckmt2b, Drer\pgm1, Drer\ckma, Drer\ckmb, Drer\ckba, Drer\ckmt2a" - "Cele\R05F9.6, Cele\F11G11.13, Cele\argk-1, Cele\F46H5.3, Cele\ZC434.8, Cele\W10C8.5, Cele\F32B5.1" "Xtro\ckb, Xtro\pgm5, Xtro\ckm, Xtro\ckmt1b, Xtro\pgm1" "Mmus\Ckb, Mmus\Pgm2, Mmus\Ckmt1, Mmus\Pgm5, Mmus\Ckm, Mmus\Ckmt2" "Hsap\PGM1, Hsap\CKMT1B, Hsap\PGM5, Hsap\CKMT1A, Hsap\CKB, Hsap\CKM, Hsap\CKMT2" " prepupal stage , P | stage P15 " " imaginal disc

, organism

" "lethal,viable,fertile,electrophoretic variant,recessive,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC21558 IE 1.960275999 0.601500766 2.093107458 -0.267178247 -0.313583096 0.902376326 FBgn0261239 Hr39 Hormone receptor-like in 39 http://flybase.org/reports/FBgn0261239 protein_coding_gene "steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q86BY9 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN001182613 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | inferred from direct assay" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN001182613 male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype spermathecum morphogenesis ; GO:0035211 | inferred from mutant phenotype hormone-mediated signaling pathway ; GO:0009755 | inferred from biological aspect of ancestor with PANTHER:PTN001182613 tissue development ; GO:0009888 | inferred from biological aspect of ancestor with PANTHER:PTN001182613 regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay" RNA polymerase II transcription factor complex ; GO:0090575 | inferred from biological aspect of ancestor with PANTHER:PTN001182613 nucleus ; GO:0005634 | inferred from direct assay "DHR39, Hr39, HR39, CG8676, i70, EP(2)2490, DHR30, FTZ-F1B, DHR39/Ftz-F1beta, NR5B1, dFTZ-F1beta, ftz-F1beta, ftz-f1beta, FTZ-F1beta, betaFTZ-E1, fs(2)neo8, fs(2)04443" "IPR016355:Nuclear hormone receptor family 5, IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR013088:Zinc finger, NHR/GATA-type" CG8676 11-Aug-17 DroID_v2017_08 "Drer\nr6a1b, Drer\raraa, Drer\nr0b2b, Drer\vdra, Drer\nr2f6a, Drer\vdrb, Drer\rargb, Drer\nr2f1b, Drer\nr2f5, Drer\nr2f2, Drer\pparg, Drer\rxraa, Drer\pparda, Drer\rxrab, Drer\nr0b2a, Drer\nr2c2, Drer\nr2e3, Drer\nr1h5, Drer\nr5a1a, Drer\rarab, Drer\ppardb, Drer\nr2e1, Drer\esrrd, Drer\nr1h4, Drer\nr2c1, Drer\esr2b, Drer\rxrbb, Drer\pparaa, Drer\rxrga, Drer\nr2f6b, Drer\nr2f1a, Drer\esrra, Drer\rxrba, Drer\nr1i2, Drer\esr1, Drer\pparab, Drer\nr3c1, Drer\ar, Drer\pgr, Drer\thrab, Drer\esr2a, Drer\esrrga, Drer\nr0b1, Drer\esrrgb" - "Cele\nhr-25, Cele\nhr-91, Cele\nhr-277, Cele\nhr-276, Cele\ZK418.10" "Xtro\nr1i2, Xtro\nr1h5, Xtro\esrra, Xtro\nr3c1, Xtro\esrrgr, Xtro\esr1, Xtro\vdr, Xtro\rxrg, Xtro\esrrg, Xtro\rarb, Xtro\nr2f2, Xtro\thrb, Xtro\esrrb, Xtro\pparg, Xtro\nr2f5, Xtro\nr2e3, Xtro\rxra, Xtro\esr2, Xtro\nr2c2, Xtro\nr2f1, Xtro\nr6a1, Xtro\ppara, Xtro\nr1h2, Xtro\ppard, Xtro\nr2f6, Xtro\nr3c2, Xtro\ar, Xtro\rarg, Xtro\rxrb, Xtro\nr0b2, Xtro\rara, Xtro\nr2c1, Xtro\pgr, Xtro\nr2e1, Xtro\nr0b1" "Mmus\Vdr, Mmus\Nr0b1, Mmus\Nr3c1, Mmus\Nr1i2, Mmus\Esrrg, Mmus\Nr1i3, Mmus\Nr2e3, Mmus\Rara, Mmus\Ar, Mmus\Nr2f6, Mmus\Rxrb, Mmus\Nr2c2, Mmus\Esrrb, Mmus\Nr1h3, Mmus\Nr3c2, Mmus\Esr1, Mmus\Nr1h4, Mmus\Rarg, Mmus\Pgr, Mmus\Rxrg, Mmus\Esrra, Mmus\Nr1h2, Mmus\Rarb, Mmus\Nr2e1, Mmus\Nr2f1, Mmus\Esr2, Mmus\Nr2c1, Mmus\Nr6a1, Mmus\Nr1h5, Mmus\Ppard, Mmus\Nr0b2, Mmus\Thrb, Mmus\Nr2f2, Mmus\Rxra, Mmus\Thra, Mmus\Pparg, Mmus\Ppara" "Hsap\AR, Hsap\ESRRG, Hsap\ESRRB, Hsap\NR2E1, Hsap\RARB, Hsap\THRB, Hsap\NR6A1, Hsap\PPARD, Hsap\NR2F2, Hsap\ESR2, Hsap\NR0B2, Hsap\NR0B1, Hsap\NR3C2, Hsap\PPARG, Hsap\RARG, Hsap\NR1I3, Hsap\RXRA, Hsap\PPARA, Hsap\RXRB, Hsap\VDR, Hsap\ESRRA, Hsap\NR1H3, Hsap\THRA, Hsap\NR1H2, Hsap\NR2F1, Hsap\RARA, Hsap\PGR, Hsap\ESR1, Hsap\NR2F6, Hsap\NR2C1, Hsap\NR1H4, Hsap\RXRG, Hsap\NR3C1, Hsap\NR2C2, Hsap\NR1I2" " embryonic stage | stage 13 , embryonic stage , embryonic stage | stage 16 , embryonic stage | early , embryonic stage -- adult stage " " stomodeum

, embryonic central nervous system

, supraesophageal ganglion

, embryonic/larval hindgut

" FBgn0037092 M6 M6 http://flybase.org/reports/FBgn0037092 protein_coding_gene - oogenesis ; GO:0048477 | inferred from mutant phenotype positive phototaxis ; GO:0046956 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001614 plasma membrane ; GO:0005886 | inferred from direct assay "dM6a, CG7540, M6, m6" IPR001614:Myelin proteolipid protein PLP CG7540 11-Aug-17 DroID_v2017_08 "Drer\gpm6bb, Drer\gpm6ba, Drer\gpm6aa, Drer\gpm6ab, Drer\plp1a, Drer\plp1b" - Cele\nmgp-1 "Xtro\gpm6a, Xtro\gpm6b, Xtro\plp1" "Mmus\Gpm6a, Mmus\Gpm6b, Mmus\Plp1" "Hsap\GPM6B, Hsap\PLP1, Hsap\GPM6A" "viable,fertile,female sterile,recessive,male fertile,short lived,visible,phototaxis defective,heat sensitive,female fertile,female semi-sterile,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" "egg,eye,ommatidium,interommatidial bristle,heat sensitive,follicle cell,border follicle cell,egg chamber" FBgn0261119 Prp19 Pre-RNA processing factor 19 http://flybase.org/reports/FBgn0261119 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from biological aspect of ancestor with PANTHER:PTN000356711 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:17896 "generation of catalytic spliceosome for first transesterification step ; GO:0000349 | inferred from biological aspect of ancestor with PANTHER:PTN000356711 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D inferred from genetic interaction with rl chromatin organization ; GO:0006325 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:17896 mRNA splicing, via spliceosome ; GO:0000398 | traceable author statement" spliceosomal complex ; GO:0005681 | traceable author statement precatalytic spliceosome ; GO:0071011 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity Prp19 complex ; GO:0000974 | inferred from biological aspect of ancestor with PANTHER:PTN000356711 Prp19 complex ; GO:0000974 | inferred from sequence or structural similarity with HGNC:17896 U2-type catalytic step 1 spliceosome ; GO:0071006 | inferred from biological aspect of ancestor with PANTHER:PTN000356711 "Prp19, CG5519, PRP19, EC2-11, l(2)07838, GPB, BcDNA:LD02793, prp19, Gbp" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR003613:U box domain, IPR013915:Pre-mRNA-splicing factor 19, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily" CG5519 11-Aug-17 DroID_v2017_08 Drer\prp19 "Scer\PRP19, Scer\TAF5" Cele\prp-19 Xtro\prpf19 Mmus\Prpf19 Hsap\PRPF19 FBgn0032819 CG10463 - http://flybase.org/reports/FBgn0032819 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 tRNA dihydrouridine synthase activity ; GO:0017150 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517" - CG10463 "IPR018517:tRNA-dihydrouridine synthase, conserved site, IPR001269:tRNA-dihydrouridine synthase, IPR013785:Aldolase-type TIM barrel, IPR000571:Zinc finger, CCCH-type" CG10463 11-Aug-17 DroID_v2017_08 Drer\dus3l Scer\DUS3 Cele\Y37E11B.5 Xtro\dus3l Mmus\Dus3l Hsap\DUS3L "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0050018 mthl13 methuselah-like 13 http://flybase.org/reports/FBgn0050018 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 response to stress ; GO:0006950 | inferred from electronic annotation with InterPro:IPR010596 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "CG30018, mthl13" "IPR023311:Methuselah ectodomain, domain 2, IPR017981:GPCR, family 2-like, IPR010596:Methuselah, N-terminal domain" CG30018 11-Aug-17 DroID_v2017_08 Drer\adgrf11 - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0267486 Ptp36E Protein tyrosine phosphatase 36E http://flybase.org/reports/FBgn0267486 protein_coding_gene "protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR000242, InterPro:IPR016130 protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from sequence model protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement" protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000242 protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity cellular_component ; GO:0005575 | no biological data available "CG7180, DPTP36E, Ptp36E, R-PTPk" "IPR029021:Protein-tyrosine phosphatase-like, IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR003595:Protein-tyrosine phosphatase, catalytic" CG7180 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-391i24.1, Drer\ptprq, Drer\LOC101884960, Drer\ptprfa, Drer\ptprea, Drer\ptprc, Drer\ptprub, Drer\ptprk, Drer\ptpreb, Drer\ptprt, Drer\ptpra, Drer\ptprna, Drer\ptprn2, Drer\ptprdb, Drer\ptpn23a, Drer\ptprsa, Drer\ptprd, Drer\ptprua, Drer\ptprnb, Drer\ptprfb" Scer\PTP1 "Cele\T13H5.1, Cele\moa-1" "Xtro\ptprm, Xtro\ptprd, Xtro\ptprk, Xtro\ptpru, Xtro\ptprs, Xtro\ptprf, Xtro\ptpra, Xtro\ptprc, Xtro\ptpre" "Mmus\Ptprn2, Mmus\Ptprz1, Mmus\Ptprn, Mmus\Ptpru, Mmus\Ptprd, Mmus\Ptprf, Mmus\Ptprt, Mmus\Ptprc, Mmus\Ptprk, Mmus\Ptprm, Mmus\Ptpre, Mmus\Ptpra, Mmus\Ptprs, Mmus\Ptprq" "Hsap\PTPRA, Hsap\PTPRT, Hsap\PTPRD, Hsap\PTPRQ, Hsap\PTPRN2, Hsap\PTPRE, Hsap\PTPRF, Hsap\PTPRU, Hsap\PTPRC, Hsap\PTPRZ1, Hsap\PTPRN, Hsap\PTPRS, Hsap\PTPRM, Hsap\PTPRK" FBgn0039152 Root Rootletin http://flybase.org/reports/FBgn0039152 protein_coding_gene - locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype auditory behavior ; GO:0031223 | inferred from mutant phenotype sensory perception of touch ; GO:0050975 | inferred from mutant phenotype ciliary basal body organization ; GO:0032053 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype ciliary rootlet ; GO:0035253 | inferred from direct assay ciliary rootlet ; GO:0035253 | colocalizes_with inferred from direct assay "CG6129, Q8IMX3_DROME, Root, Rootletin" - CG6129 11-Aug-17 DroID_v2017_08 "Drer\tsga10, Drer\jmy, Drer\si:ch73-242m19.1, Drer\crocc2, Drer\si:dkey-230p4.1, Drer\cep135, Drer\cep128, Drer\LOC101886398" - "Cele\lfi-1, Cele\che-10" "Xtro\crocc, Xtro\crocc2, Xtro\whamm, Xtro\jmy" "Mmus\Jmy, Mmus\Cep250, Mmus\Tsga10, Mmus\Cep135, Mmus\Whamm, Mmus\Crocc, Mmus\Crocc2" "Hsap\WHAMM, Hsap\CEP135, Hsap\JMY, Hsap\CROCC, Hsap\CROCC2, Hsap\TSGA10, Hsap\CEP250" viable FBgn0037816 CG6345 - http://flybase.org/reports/FBgn0037816 protein_coding_gene "transferase activity ; GO:0016740 | inferred from electronic annotation with InterPro:IPR005839 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR005839, InterPro:IPR013848, InterPro:IPR020612" tRNA modification ; GO:0006400 | inferred from electronic annotation with InterPro:IPR006463 regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | inferred from sequence or structural similarity with UniProtKB:Q9JLH6 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR006463 "149631_at, CG6345" "IPR002792:TRAM domain, IPR005839:Methylthiotransferase, IPR006638:Elongator protein 3/MiaB/NifB, IPR007197:Radical SAM, IPR013848:Methylthiotransferase, N-terminal, IPR023404:Radical SAM, alpha/beta horseshoe, IPR006463:tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB, IPR020612:Methylthiotransferase, conserved site" CG6345 11-Aug-17 DroID_v2017_08 Drer\cdk5rap1 - "Cele\F25B5.5, Cele\Y92H12BL.1" Xtro\cdk5rap1 "Mmus\Cdk5rap1, Mmus\Cdkal1" "Hsap\CDK5RAP1, Hsap\CDKAL1" viable FBgn0034791 EMC8-9 ER Membrane protein Complex 8-9 http://flybase.org/reports/FBgn0034791 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available endomembrane system ; GO:0012505 | inferred from direct assay ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN000309985 microtubule associated complex ; GO:0005875 | inferred from direct assay "BcDNA:SD01117, CG3501, EMC8-9, EMC8/9" IPR005366:ER membrane protein complex subunit 8/9 CG3501 11-Aug-17 DroID_v2017_08 "Drer\emc8, Drer\emc9" - Cele\F25H2.4 "Xtro\emc8, Xtro\emc9" "Mmus\Emc8, Mmus\Emc9" "Hsap\EMC8, Hsap\EMC9" viable FBgn0031575 Cep97 Centrosomal protein 97kDa http://flybase.org/reports/FBgn0031575 protein_coding_gene - negative regulation of centriole elongation ; GO:1903723 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype pericentriolar material ; GO:0000242 | inferred from direct assay "CT13231, Cep97, DCep97, CG3980, cep97" "IPR000048:IQ motif, EF-hand binding site, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG3980 11-Aug-17 DroID_v2017_08 "Drer\lrrcc1, Drer\si:dkey-267j14.7, Drer\lrguk, Drer\ppp1r7, Drer\si:ch211-103e16.5, Drer\lrrc6, Drer\drc3, Drer\lrrc9, Drer\lrrc61, Drer\cep97, Drer\lrriq1, Drer\lrrc23" "Scer\NUD1, Scer\SDS22" "Cele\R02F11.4, Cele\F09G8.5" "Xtro\cep97, Xtro\lrrc9, Xtro\lrrcc1, Xtro\ppp1r7, Xtro\lrrc6, Xtro\drc3, Xtro\lrrc23, Xtro\dnal1, Xtro\lrrc56, Xtro\lrrc49" "Mmus\Lrrc6, Mmus\Lrrc9, Mmus\Lrriq1, Mmus\Lrrcc1, Mmus\Lrrc56, Mmus\Lrrc23, Mmus\Lrriq3, Mmus\Lrrc46, Mmus\1810043G02Rik, Mmus\Lrrc48, Mmus\Lrrc61, Mmus\Cep97, Mmus\Ppp1r7, Mmus\Lrguk, Mmus\Lrrc43, Mmus\Dnal1, Mmus\Lrrc49" "Hsap\LRRC49, Hsap\LRRIQ3, Hsap\LRRC23, Hsap\PPP1R7, Hsap\LRRC6, Hsap\C21orf2, Hsap\LRRC56, Hsap\LRRC43, Hsap\DNAL1, Hsap\LRRC46, Hsap\LRGUK, Hsap\DRC3, Hsap\LRRCC1, Hsap\CEP97, Hsap\LRRC61, Hsap\LRRIQ1" viable FBgn0027055 CSN3 COP9 signalosome subunit 3 http://flybase.org/reports/FBgn0027055 - protein_coding_gene NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from mutant phenotype germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000079485 male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay germ cell development ; GO:0007281 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from sequence or structural similarity with HGNC:2239 protein stabilization ; GO:0050821 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity with MGI:MGI:1349409 COP9 signalosome ; GO:0008180 | inferred from direct assay COP9 signalosome ; GO:0008180 | non-traceable author statement COP9 signalosome ; GO:0008180 | inferred from mutant phenotype "Dch3, DCH3, CH3, CG18332, CSN3, Csn3, FBgn0027055, dCSN3" "IPR000717:Proteasome component (PCI) domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG18332 11-Aug-17 DroID_v2017_08 Drer\cops3 Scer\RPN3 "Cele\rpn-3, Cele\csn-3" Xtro\cops3 Mmus\Cops3 Hsap\COPS3 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC25919 K 0.450105356 -0.441053706 0.274359368 -1.100060675 1.752507415 1.526982907 FBgn0042710 Hex-t2 Hex-t2 http://flybase.org/reports/FBgn0042710 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001312, InterPro:IPR019807, InterPro:IPR022672, InterPro:IPR022673 glucose binding ; GO:0005536 | inferred from electronic annotation with InterPro:IPR001312 hexokinase activity ; GO:0004396 | inferred from sequence or structural similarity with SGD:S000001949 mannokinase activity ; GO:0019158 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 fructokinase activity ; GO:0008865 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 glucokinase activity ; GO:0004340 | inferred from biological aspect of ancestor with PANTHER:PTN000455350" carbohydrate phosphorylation ; GO:0046835 | inferred from electronic annotation with InterPro:IPR001312 glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 cellular glucose homeostasis ; GO:0001678 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 glucose metabolic process ; GO:0006006 | inferred from sequence or structural similarity with SGD:S000001949 glycolytic process ; GO:0006096 | inferred from sequence or structural similarity with SGD:S000001949 mannose metabolic process ; GO:0006013 | inferred from sequence or structural similarity with SGD:S000001949 fructose metabolic process ; GO:0006000 | inferred from sequence or structural similarity with SGD:S000001949 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 "HK, CG5443, Hex, CG32849, anon-WO0140519.203, Hex-t2, Hex-T2" "IPR001312:Hexokinase, IPR019807:Hexokinase, binding site, IPR022672:Hexokinase, N-terminal, IPR022673:Hexokinase, C-terminal" CG32849 11-Aug-17 DroID_v2017_08 "Drer\hk1, Drer\hk2, Drer\gck, Drer\hkdc1" "Scer\YLR446W, Scer\HXK2, Scer\EMI2, Scer\HXK1, Scer\GLK1" "Cele\hxk-3, Cele\hxk-1, Cele\hxk-2" "Xtro\hk2, Xtro\gck, Xtro\hk1" "Mmus\Hk1, Mmus\Gck, Mmus\Hkdc1, Mmus\Hk2, Mmus\Hk3" "Hsap\HKDC1, Hsap\HK3, Hsap\HK2, Hsap\GCK, Hsap\HK1" viable FBgn0034068 casp caspar http://flybase.org/reports/FBgn0034068 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell death ; GO:0008219 | inferred from electronic annotation with InterPro:IPR033043 negative regulation of peptidoglycan recognition protein signaling pathway ; GO:0061060 | inferred from mutant phenotype negative regulation of proteolysis ; GO:0045861 | inferred from mutant phenotype negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0002814 | inferred from mutant phenotype cytoplasm ; GO:0005737 | non-traceable author statement "casp, CG8400, CASP, Casp, FAF1" "IPR001012:UBX domain, IPR006577:UAS, IPR012336:Thioredoxin-like fold, IPR033043:FAS-associated factor 1, UBX domain, IPR029071:Ubiquitin-related domain" CG8400 11-Aug-17 DroID_v2017_08 Drer\faf1 "Scer\UBX2, Scer\UBX3" "Cele\ubxn-3, Cele\ubc-23, Cele\H40L08.1" "Xtro\faf2, Xtro\faf1" "Mmus\Faf1, Mmus\Faf2" "Hsap\FAF1, Hsap\FAF2" "immune response defective,viable,fertile" fat body FBgn0039139 Ime4 Inducer of meiosis 4 http://flybase.org/reports/FBgn0039139 protein_coding_gene mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity ; GO:0016422 | inferred from biological aspect of ancestor with PANTHER:PTN000302828 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity ; GO:0016422 | inferred from sequence or structural similarity with UniProtKB:Q86U44 "dosage compensation ; GO:0007549 | inferred from mutant phenotype inferred from genetic interaction with Sxl ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype sex determination ; GO:0007530 | inferred from genetic interaction with Sxl sex determination ; GO:0007530 | inferred from mutant phenotype inferred from genetic interaction with Sxl mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000981980 germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype mRNA methylation ; GO:0080009 | inferred from mutant phenotype RNA methylation ; GO:0001510 | inferred from sequence or structural similarity with UniProtKB:Q86U44 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype primary miRNA methylation ; GO:1990744 | inferred from biological aspect of ancestor with PANTHER:PTN000981980 regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype dosage compensation ; GO:0007549 | inferred from genetic interaction with Sxl regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay MIS complex ; GO:0036396 | inferred from biological aspect of ancestor with PANTHER:PTN000302828 nuclear speck ; GO:0016607 | inferred from biological aspect of ancestor with PANTHER:PTN000302828 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q86U44 "IME4, Ime4, ime4, CG5933, Mta70, MTA70" "IPR007757:MT-A70-like, IPR025848:mRNA (2-O-methyladenosine-N(6)-)-methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG5933 11-Aug-17 DroID_v2017_08 Drer\mettl3 Scer\IME4 - Xtro\mettl3 Mmus\Mettl3 Hsap\METTL3 "partially lethal - majority die,semi-fertile,viable,visible" "egg chamber,nurse cell,supernumerary,oocyte,follicle cell,interfollicle cell,female germline cyst,mesothoracic tergum" FBgn0027550 CG6495 - http://flybase.org/reports/FBgn0027550 - protein_coding_gene - regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype - "GH10711, BcDNA:GH10711, CG6495" "IPR011106:Seven cysteines, N-terminal, IPR013980:MANSC domain, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG6495 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-215d9.1, Drer\si:ch211-193k19.1, Drer\spint1a, Drer\lrp11, Drer\spint1b" - - "Xtro\spint1, Xtro\lrp11" "Mmus\AU040320, Mmus\Lrp11, Mmus\Spint1, Mmus\D130043K22Rik" "Hsap\KIAA0319, Hsap\KIAA0319L, Hsap\LRP11, Hsap\SPINT1" viable FBgn0033500 CG12913 - http://flybase.org/reports/FBgn0033500 protein_coding_gene acetylgalactosaminyltransferase activity ; GO:0008376 | inferred from electronic annotation with InterPro:IPR008428 acetylgalactosaminyltransferase activity ; GO:0008376 | non-traceable author statement chondroitin sulfate biosynthetic process ; GO:0030206 | non-traceable author statement wound healing ; GO:0042060 | inferred from mutant phenotype Golgi cisterna membrane ; GO:0032580 | inferred from electronic annotation with InterPro:IPR008428 "CG12913, dCSGalNAcT1" "IPR008428:Chondroitin N-acetylgalactosaminyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases" CG12913 11-Aug-17 DroID_v2017_08 "Drer\csgalnact2, Drer\csgalnact1b, Drer\b4galnt4a, Drer\b4galnt3a, Drer\chsy1, Drer\chsy3, Drer\b4galnt4b, Drer\csgalnact1a, Drer\b4galnt3b" - Cele\sqv-5 "Xtro\csgalnact2, Xtro\csgalnact1, Xtro\b4galnt3, Xtro\b4galnt4, Xtro\chsy1" "Mmus\Csgalnact2, Mmus\Chsy1, Mmus\B4galnt3, Mmus\Csgalnact1, Mmus\Chsy3, Mmus\B4galnt4" "Hsap\B4GALNT4, Hsap\CSGALNACT2, Hsap\B4GALNT3, Hsap\CSGALNACT1, Hsap\CHSY1, Hsap\CHSY3" viable DRSC06228 K 0.142427604 0.386884142 -0.104862685 0.213625082 1.590965295 0.243722824 FBgn0037263 slx1 nuclease slx1 http://flybase.org/reports/FBgn0037263 protein_coding_gene 5'-flap endonuclease activity ; GO:0017108 | inferred from electronic annotation with InterPro:IPR027520 protein binding ; GO:0005515 | inferred from physical interaction with mus312 endodeoxyribonuclease activity ; GO:0004520 | inferred from sequence or structural similarity with SGD:S000000432 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VS48 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR027520 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype Slx1-Slx4 complex ; GO:0033557 | inferred from direct assay Slx1-Slx4 complex ; GO:0033557 | inferred from sequence or structural similarity with SGD:S000000432 "slx1, CG1827, SLX1, CG18271" "IPR000305:GIY-YIG nuclease superfamily, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027520:Structure-specific endonuclease subunit Slx1, IPR026850:FANCL C-terminal domain" CG18271 11-Aug-17 DroID_v2017_08 Drer\slx1b Scer\SLX1 Cele\slx-1 Xtro\slx1a Mmus\Slx1b "Hsap\SLX1A, Hsap\SLX1B" radiation sensitive FBgn0034913 Snap29 Synaptosomal-associated protein 29kDa http://flybase.org/reports/FBgn0034913 protein_coding_gene "SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNAP receptor activity ; GO:0005484 | inferred from physical interaction with Syx17, Vamp7 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000447753 SNARE binding ; GO:0000149 | inferred from physical interaction with Syb inferred from physical interaction with Syx1A inferred from physical interaction with Syx4 inferred from physical interaction with Sec22 inferred from physical interaction with Vamp7 inferred from physical interaction with Syx7 SNARE binding ; GO:0000149 | inferred from physical interaction with Syx17, Vamp7" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype synaptic vesicle fusion to presynaptic active zone membrane ; GO:0031629 | inferred from biological aspect of ancestor with PANTHER:PTN000447754 Golgi organization ; GO:0007030 | inferred from mutant phenotype negative regulation of secretion by cell ; GO:1903531 | inferred from mutant phenotype synaptic vesicle priming ; GO:0016082 | inferred from biological aspect of ancestor with PANTHER:PTN000447754 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000447752 SNARE complex ; GO:0031201 | inferred from direct assay "SNAP-29, CG11173, Ubisnap, usnp, Snap29, MENE (2R)-E, MENE(2R)-E, ubisnap, SNAP29, dSNAP-29" IPR000727:Target SNARE coiled-coil homology domain CG11173 11-Aug-17 DroID_v2017_08 "Drer\snap23.2, Drer\snap23.1, Drer\snap25b, Drer\snap29, Drer\snap25a, Drer\zgc:101731" "Scer\SEC9, Scer\SPO20" Cele\snap-29 "Xtro\snap47, Xtro\snap25, Xtro\snap29, Xtro\snap23" "Mmus\Snap47, Mmus\Snap29, Mmus\Snap25, Mmus\Snap23" "Hsap\SNAP47, Hsap\SNAP25, Hsap\SNAP29, Hsap\SNAP23" "lethal,partially lethal - majority die" embryonic/larval fat body | third instar larval stage FBgn0035577 CG13708 - http://flybase.org/reports/FBgn0035577 protein_coding_gene - axon guidance ; GO:0007411 | inferred from biological aspect of ancestor with PANTHER:PTN001222848 lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CT33170, CG13708" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG13708 11-Aug-17 DroID_v2017_08 "Drer\drc3, Drer\lrguk, Drer\lrrc9, Drer\ppp1r7, Drer\si:ch211-103e16.5, Drer\lrrcc1, Drer\lrrc6, Drer\cep97, Drer\lrriq1, Drer\lrrc61, Drer\lrrc23, Drer\si:dkey-267j14.7" "Scer\SDS22, Scer\NUD1" Cele\egg-6 "Xtro\drc3, Xtro\cep97, Xtro\lrrc6, Xtro\dnal1, Xtro\lrrcc1, Xtro\ppp1r7, Xtro\lrrc9, Xtro\lrrc49, Xtro\lrrc23, Xtro\lrrc56" "Mmus\Lrrc48, Mmus\Ppp1r7, Mmus\Lrrc61, Mmus\Lrrc23, Mmus\Tlr12, Mmus\Cep97, Mmus\Lrrc6, Mmus\Lrrc49, Mmus\Lrrc46, Mmus\Lrrc43, Mmus\Lrrcc1, Mmus\Lrguk, Mmus\Lrriq3, Mmus\Lrriq1, Mmus\Lrrc9, Mmus\Dnal1, Mmus\Lrrc56" "Hsap\LRRIQ3, Hsap\LRRC6, Hsap\LRRIQ1, Hsap\LRRCC1, Hsap\DNAL1, Hsap\LRGUK, Hsap\LRRC56, Hsap\LRRC46, Hsap\LRRC61, Hsap\LRRC49, Hsap\CEP97, Hsap\LRRC23, Hsap\LRRC43, Hsap\DRC3, Hsap\PPP1R7" "viable,visible" chaeta FBgn0003076 Pgm phosphoglucose mutase http://flybase.org/reports/FBgn0003076 FBgn0036572 protein_coding_gene magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR016066 phosphoglucomutase activity ; GO:0004614 | inferred from sequence or structural similarity with UniProtKB:P36871 phosphoglucomutase activity ; GO:0004614 | inferred from direct assay phosphoglycerate mutase activity ; GO:0004619 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype glycogen biosynthetic process ; GO:0005978 | inferred from mutant phenotype glucose metabolic process ; GO:0006006 | inferred from biological aspect of ancestor with PANTHER:PTN000501426 lateral inhibition ; GO:0046331 | inferred from mutant phenotype galactose catabolic process ; GO:0019388 | inferred from biological aspect of ancestor with PANTHER:PTN000501426 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000501326 "pgm, PGM, CG5165, PGM-1, Pgm, Pgm-1, PGM1" "IPR005841:Alpha-D-phosphohexomutase superfamily, IPR005843:Alpha-D-phosphohexomutase, C-terminal, IPR005844:Alpha-D-phosphohexomutase, alpha/beta/alpha domain I, IPR005845:Alpha-D-phosphohexomutase, alpha/beta/alpha domain II, IPR005846:Alpha-D-phosphohexomutase, alpha/beta/alpha domain III, IPR016055:Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III, IPR016066:Alpha-D-phosphohexomutase, conserved site" CG5165 11-Aug-17 DroID_v2017_08 "Drer\pgm1, Drer\ckmt2b, Drer\ckmt1, Drer\ckma, Drer\pgm5, Drer\ckbb" "Scer\PGM1, Scer\PGM2" "Cele\R05F9.6, Cele\F32B5.1" "Xtro\ckmt1b, Xtro\pgm1, Xtro\pgm5, Xtro\ckb, Xtro\ckm" "Mmus\Ckb, Mmus\Pgm5, Mmus\Ckmt1, Mmus\Ckm, Mmus\Ckmt2, Mmus\Pgm2" "Hsap\CKMT1B, Hsap\CKMT1A, Hsap\CKMT2, Hsap\PGM1, Hsap\CKB, Hsap\PGM5, Hsap\CKM" "electrophoretic variant,slow,lethal,recessive,viable,fertile,fast,intermediate,visible" chaeta FBgn0050036 CG30036 - http://flybase.org/reports/FBgn0050036 protein_coding_gene galactosyltransferase activity ; GO:0008378 | inferred from electronic annotation with InterPro:IPR002659 protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR002659 Golgi organization ; GO:0007030 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "CG8976, CG30036" "IPR002659:Glycosyl transferase, family 31" CG30036 11-Aug-17 DroID_v2017_08 "Drer\zgc:194330, Drer\b3galnt2, Drer\b3galt4, Drer\LOC100535930, Drer\b3gnt5a, Drer\b3gnt3, Drer\LOC565422, Drer\b3gnt5b, Drer\b3gnt2b, Drer\zgc:194551, Drer\b3gnt2a, Drer\b3galt2, Drer\b3gnt7, Drer\b3gnt2l, Drer\si:ch211-126g16.11, Drer\b3galt1b, Drer\b3gnt7l, Drer\si:dkey-175m17.6, Drer\si:dkeyp-98a7.1, Drer\b3galt1a, Drer\si:ch73-195i19.3, Drer\b3gnt9, Drer\LOC100333524, Drer\si:dkey-160o24.3, Drer\zgc:86586" - "Cele\T15D6.5, Cele\T09F5.1, Cele\C47F8.5, Cele\bre-2, Cele\F14B6.4, Cele\bus-2, Cele\bus-17, Cele\B0024.15, Cele\bre-5, Cele\F14B6.6, Cele\C47F8.3, Cele\E03H4.11, Cele\T09E11.10, Cele\C54C8.3" "Xtro\LOC100494986, Xtro\b3galt2, Xtro\b3galt4, Xtro\b3gnt3, Xtro\b3gnt2, Xtro\b3galnt2, Xtro\b3gnt6, Xtro\b3gnt5, Xtro\LOC100487553, Xtro\LOC100494668, Xtro\LOC100489267, Xtro\b3galt1, Xtro\LOC100493833, Xtro\b3gnt4, Xtro\b3gnt3" "Mmus\B3gnt6, Mmus\B3gnt8, Mmus\B3gnt5, Mmus\B3gnt9, Mmus\B3galnt1, Mmus\B3galt1, Mmus\B3galt2, Mmus\B3galt5, Mmus\B3gnt3, Mmus\B3gnt7, Mmus\B3gnt4, Mmus\B3galnt2, Mmus\B3galt4, Mmus\B3gnt2" "Hsap\B3GNT7, Hsap\B3GALT4, Hsap\B3GNT6, Hsap\B3GNT9, Hsap\B3GNT3, Hsap\B3GNT4, Hsap\B3GALNT2, Hsap\B3GNT8, Hsap\B3GALT2, Hsap\B3GALT1, Hsap\B3GALT5, Hsap\B3GNT5, Hsap\B3GALNT1, Hsap\B3GNT2" FBgn0015038 Cyp9b1 Cytochrome P450-9b1 http://flybase.org/reports/FBgn0015038 - protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972" - "9b1, P450, P-450, CG4485, Cyp9b1, CYP9B1" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV, IPR017972:Cytochrome P450, conserved site" CG4485 11-Aug-17 DroID_v2017_08 "Drer\cyp3a65, Drer\cyp4t8, Drer\cyp3c3, Drer\cyp4f3, Drer\cyp3c1, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp3c4, Drer\cyp3c2, Drer\tbxas1" Scer\ERG11 "Cele\cyp-13A12, Cele\cyp-13A7, Cele\cyp-13A11, Cele\cyp-44A1, Cele\cyp-29A4, Cele\cyp-43A1, Cele\cyp-31A3, Cele\cyp-13B1, Cele\cyp-13A8, Cele\cyp-42A1, Cele\cyp-25A1, Cele\cyp-13A10, Cele\cyp-25A4, Cele\cyp-29A2, Cele\cyp-13A6, Cele\cyp-13A2, Cele\cyp-13A1, Cele\cyp-13A4, Cele\cyp-37B1, Cele\cyp-25A6, Cele\cyp-31A2, Cele\cyp-25A2, Cele\cyp-32B1, Cele\cyp-13B2, Cele\cyp-25A3, Cele\cyp-13A5, Cele\cyp-13A3, Cele\cyp-29A3, Cele\cyp-32A1" "Xtro\tbxas1, Xtro\cyp3a5, Xtro\LOC100494419, Xtro\cyp3a4" "Mmus\Cyp3a59, Mmus\Cyp4a12a, Mmus\Cyp3a11, Mmus\Cyp3a13, Mmus\Cyp3a41a, Mmus\Cyp4a32, Mmus\Cyp4a14, Mmus\Cyp3a16, Mmus\Cyp4f14, Mmus\Cyp4a10, Mmus\Cyp3a57, Mmus\Cyp4f18, Mmus\Tbxas1, Mmus\Cyp4a31, Mmus\Cyp4b1, Mmus\Cyp4f16, Mmus\Cyp4f15, Mmus\Cyp3a25, Mmus\Cyp3a41b, Mmus\Cyp4f13, Mmus\Cyp4f39, Mmus\Cyp4v3, Mmus\Cyp4f37, Mmus\Cyp4a12b, Mmus\Cyp3a44" "Hsap\CYP4Z1, Hsap\CYP4F22, Hsap\CYP4B1, Hsap\CYP3A43, Hsap\CYP4V2, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4F3, Hsap\CYP4F2, Hsap\CYP4A11, Hsap\CYP4F11, Hsap\TBXAS1, Hsap\CYP3A7, Hsap\CYP4X1, Hsap\CYP3A4, Hsap\CYP4F12, Hsap\CYP4A22, Hsap\CYP4F8, Hsap\CYP3A5" viable FBgn0013751 Awh Arrowhead http://flybase.org/reports/FBgn0013751 FBgn0002195 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR009057 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:O60663" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with UniProtKB:O60663 compound eye development ; GO:0048749 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:O60663 "l(3)63Ea, l(3)63Ea/Awh, l(3)64Ea, l63Ea, l(3)SH9, CG1072, Awh, awh" "IPR001356:Homeobox domain, IPR001781:Zinc finger, LIM-type, IPR009057:Homeobox domain-like" CG1072 11-Aug-17 DroID_v2017_08 "Drer\pdlim3b, Drer\dmbx1b, Drer\lhx6, Drer\pax6a, Drer\ldb3a, Drer\lhx8a, Drer\pdlim5b, Drer\pitx1, Drer\hoxb8a, Drer\mxtx2, Drer\LOC799481, Drer\pitx3, Drer\si:ch211-236k19.2, Drer\pax6b, Drer\gsc, Drer\dmbx1a, Drer\shox, Drer\shox2, Drer\pdlim7" "Scer\PHO2, Scer\YHP1, Scer\PXL1" "Cele\ceh-45, Cele\vab-3, Cele\ceh-51, Cele\lim-4, Cele\alp-1" "Xtro\gsc, Xtro\hoxb8, Xtro\lhx8, Xtro\pdlim5, Xtro\lhx6, Xtro\pitx1, Xtro\shox2, Xtro\pitx3" "Mmus\Lhx6, Mmus\Shox2, Mmus\Pitx1, Mmus\Pdlim1, Mmus\Pax6, Mmus\Gsc, Mmus\Dmbx1, Mmus\Gsc2, Mmus\Pdlim7, Mmus\Pitx3, Mmus\Pdlim3, Mmus\Lhx8, Mmus\Pdlim5, Mmus\Ldb3" "Hsap\PAX6, Hsap\DMBX1, Hsap\LPXN, Hsap\PDLIM7, Hsap\LHX6, Hsap\HOXB8, Hsap\PDLIM1, Hsap\LHX8, Hsap\PITX1, Hsap\PDLIM3, Hsap\LDB3, Hsap\PITX3, Hsap\GSC2, Hsap\GSC, Hsap\SHOX, Hsap\SHOX2" "lethal,recessive,visible,dominant,viable,female fertile,male fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "eye,histoblast nest,salivary gland imaginal ring,eye-antennal disc,photoreceptor cell,precursor,abdominal segment,somatic clone,pupal spiracle,polytene chromosome puff,wing,ventral,vibrissae,anterior vertical bristle,posterior vertical bristle,capitellum,genitalia,coxa,femur,wing disc,eye disc,somatic clone | third instar larval stage" FBgn0259099 DCX-EMAP Doublecortin-domain-containing echinoderm-microtubule-associated protein http://flybase.org/reports/FBgn0259099 protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR003533 melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype microtubule cytoskeleton ; GO:0015630 | inferred from biological aspect of ancestor with PANTHER:PTN000347035 sensory dendrite ; GO:0071683 | inferred from direct assay "CG13466, anon-71Aa, CG13467, CG42247, DCX-EMAP, dmEMAP" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR003533:Doublecortin domain, IPR005108:HELP, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR011042:Six-bladed beta-propeller, TolB-like" CG42247 11-Aug-17 DroID_v2017_08 "Drer\rp1, Drer\si:dkey-1f12.3, Drer\dcdc2b, Drer\eml3, Drer\eml2, Drer\eml6, Drer\dclk2a, Drer\rp1l1b, Drer\rp1l1a, Drer\eml1" - "Cele\Y41C4A.32, Cele\zyg-8, Cele\elp-1" "Xtro\eml2, Xtro\dcx, Xtro\dclk2, Xtro\eml3, Xtro\eml6, Xtro\eml1, Xtro\dcdc2, Xtro\eml4" "Mmus\Rp1l1, Mmus\Eml4, Mmus\Dcdc2a, Mmus\Eml5, Mmus\Eml6, Mmus\Dclk1, Mmus\Dcdc2b, Mmus\Rp1, Mmus\Eml3, Mmus\Dclk2, Mmus\Eml2, Mmus\Eml1, Mmus\Dcx, Mmus\Dcdc2c" "Hsap\RP1, Hsap\DCLK1, Hsap\EML6, Hsap\EML5, Hsap\DCX, Hsap\EML3, Hsap\DCDC2, Hsap\EML2, Hsap\EML4, Hsap\DCDC2B, Hsap\EML1, Hsap\RP1L1, Hsap\DCDC2C" DRSC23492 IK -1.37967219 -1.836766142 -0.291744595 0.435675588 -1.572492291 -0.058173641 FBgn0261871 dpr2 defective proboscis extension response 2 http://flybase.org/reports/FBgn0261871 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "dpr2, CG14068, Dpr-2, CT33638, CG14067, CG33507, BP1042, Dpr2, Flk" "IPR003598:Immunoglobulin subtype 2, IPR013098:Immunoglobulin I-set, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype" CG33507 11-Aug-17 DroID_v2017_08 "Drer\nitr3c, Drer\kirrela, Drer\LOC100333196, Drer\si:ch1073-459j12.1, Drer\lrit3a, Drer\kirrelb, Drer\kirrel3l, Drer\LOC101885444, Drer\paplna, Drer\lrit1a, Drer\nitr1j, Drer\nitr1h, Drer\nitr3a, Drer\nitr1o, Drer\ncam1b, Drer\kirrel3a, Drer\dscama, Drer\nitr1k, Drer\nitr1m, Drer\lrit3b, Drer\nitr13, Drer\ush2a, Drer\igsf9a, Drer\si:ch211-163c2.2, Drer\igsf9bb, Drer\sdk1a, Drer\kirrel3b, Drer\sdk1b, Drer\si:dkey-65b12.12, Drer\itgb4, Drer\lrit1b, Drer\nitr1i, Drer\LOC101885725, Drer\nitr1c" - Cele\zig-8 "Xtro\nfasc, Xtro\papln, Xtro\lrit3, Xtro\igsf9b, Xtro\obsl1, Xtro\kirrel2" "Mmus\Igsf9b, Mmus\Kirrel2, Mmus\Lrit1, Mmus\Kirrel, Mmus\Sdk1, Mmus\Amica1, Mmus\Kirrel3, Mmus\Lrit3, Mmus\Ptprq, Mmus\Papln, Mmus\Gm5150" "Hsap\IGSF9B, Hsap\SIRPB2, Hsap\LRIT1, Hsap\LRIT3, Hsap\KIRREL3, Hsap\SDK1, Hsap\USH2A, Hsap\PAPLN, Hsap\KIRREL, Hsap\KIRREL2" FBgn0041183 Tep1 Thioester-containing protein 1 http://flybase.org/reports/FBgn0041183 protein_coding_gene "endopeptidase inhibitor activity ; GO:0004866 | inferred from electronic annotation with InterPro:IPR001599, InterPro:IPR002890" - extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR011626 "Tep1, Tep-1, tep1, dTEPI, BG:DS00365.2, CG18096, TEP1mel, TEP1, TepI, Tep I, Tep 1" "IPR002890:Alpha-2-macroglobulin, N-terminal, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR009048:Alpha-macroglobulin, receptor-binding, IPR011625:Alpha-2-macroglobulin, N-terminal 2, IPR011626:Alpha-macroglobulin complement component, IPR019742:Alpha-2-macroglobulin, conserved site, IPR013783:Immunoglobulin-like fold, IPR019565:Alpha-2-macroglobulin, thiol-ester bond-forming, IPR001599:Alpha-2-macroglobulin" CG18096 11-Aug-17 DroID_v2017_08 "Drer\c3a.4, Drer\c3a.3, Drer\c3b.1, Drer\c4, Drer\si:dkey-8k3.2, Drer\c3a.2, Drer\c3b.2, Drer\zgc:171426, Drer\si:dkey-46g23.2, Drer\cpamd8, Drer\cd109, Drer\si:dkey-52d15.2, Drer\c3a.6, Drer\zgc:165518, Drer\c5, Drer\a2ml, Drer\c3a.1" - Cele\tep-1 "Xtro\ovos2, Xtro\c4a, Xtro\c5, Xtro\c3, Xtro\a2ml1" "Mmus\Cd109, Mmus\C4b, Mmus\Mug2, Mmus\AI182371, Mmus\C3, Mmus\BC048546, Mmus\Hc, Mmus\A2m" "Hsap\CPAMD8, Hsap\C3, Hsap\A2ML1, Hsap\A2M, Hsap\C4B_2, Hsap\C4A, Hsap\C5, Hsap\C4B, Hsap\CD109" viable FBgn0053497 Sdic2 Sperm-specific dynein intermediate chain 2 http://flybase.org/reports/FBgn0053497 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 biological_process ; GO:0008150 | no biological data available cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 sperm flagellum ; GO:0036126 | inferred from sequence or structural similarity with Sdic1 "CG33497, Sdic2, Sdic:CG33497" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2" CG33497 11-Aug-17 DroID_v2017_08 "Drer\dync1i2b, Drer\dync1i1, Drer\dnai1.1, Drer\LOC103908626, Drer\dnai2a" Scer\PAC11 Cele\dyci-1 "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Dync1i2, Mmus\Dync1i1, Mmus\Wdr63" "Hsap\WDR60, Hsap\DYNC1I1, Hsap\DYNC1I2" FBgn0034796 CG3700 - http://flybase.org/reports/FBgn0034796 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP48, c-SP48, CG3700" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG3700 11-Aug-17 DroID_v2017_08 - - "Cele\try-3, Cele\svh-1, Cele\try-1" - "Mmus\Hgfac, Mmus\Plat, Mmus\F12, Mmus\Habp2, Mmus\Prss12, Mmus\Plau" - FBgn0032456 MRP Multidrug-Resistance like Protein 1 http://flybase.org/reports/FBgn0032456 protein_coding_gene "organic anion transmembrane transporter activity ; GO:0008514 | inferred from electronic annotation with InterPro:IPR030247 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to movement of substances ; GO:0043492 | inferred from direct assay ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" response to toxic substance ; GO:0009636 | inferred from expression pattern transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 renal tubular secretion ; GO:0097254 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "CG6214, dMRP/CG6214, dMRP, MRP, MRP1, dMRP1, lincRNA.123, Mrp, ABCC1, Mrp1" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR005292:Multi drug resistance-associated protein, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR030247:Canalicular multispecific organic anion transporter 1" CG6214 11-Aug-17 DroID_v2017_08 "Drer\abcc6a, Drer\LOC100329706, Drer\abcc9, Drer\abcc2, Drer\abcc4, Drer\abcc8, Drer\abcc12, Drer\abcc6b.2, Drer\abcc13, Drer\abcc5, Drer\abcc3, Drer\abcc1, Drer\abcc10, Drer\cftr" "Scer\YOR1, Scer\BPT1, Scer\VMR1, Scer\YKR104W, Scer\NFT1, Scer\STE6, Scer\YBT1, Scer\YCF1" "Cele\mrp-3, Cele\mrp-1, Cele\mrp-2, Cele\mrp-6, Cele\cft-1, Cele\mrp-4, Cele\mrp-7, Cele\mrp-8, Cele\mrp-5" "Xtro\cftr, Xtro\abcc3, Xtro\abcc1, Xtro\abcc4, Xtro\abcc6, Xtro\abcc10" "Mmus\Abcc2, Mmus\Abcc10, Mmus\Abcc9, Mmus\Abcc3, Mmus\Abcc8, Mmus\Abcc12, Mmus\Cftr, Mmus\Abcc1, Mmus\Abcc6, Mmus\Abcc5, Mmus\Abcc4" "Hsap\CFTR, Hsap\ABCC8, Hsap\ABCC3, Hsap\ABCC10, Hsap\ABCC2, Hsap\ABCC12, Hsap\ABCC4, Hsap\ABCC5, Hsap\ABCC1, Hsap\ABCC11, Hsap\ABCC9, Hsap\ABCC6" "viable,fertile" FBgn0050394 CG30394 - http://flybase.org/reports/FBgn0050394 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from biological aspect of ancestor with PANTHER:PTN000535793 - "CG15670, CG10500, anon-WO0172774.188, anon-WO0172774.187, CG30394" "IPR013057:Amino acid transporter, transmembrane domain" CG30394 11-Aug-17 DroID_v2017_08 "Drer\slc38a10, Drer\slc38a9, Drer\slc38a5b, Drer\slc38a7, Drer\slc38a11, Drer\slc38a8b, Drer\LOC100536170, Drer\slc38a2, Drer\slc38a8a, Drer\slc38a5a, Drer\slc38a4, Drer\slc38a6" "Scer\AVT2, Scer\AVT5, Scer\AVT6, Scer\AVT7" Cele\Y51F10.4 "Xtro\slc38a3, Xtro\slc38a5, Xtro\slc38a9, Xtro\slc38a11, Xtro\slc38a6, Xtro\slc38a2, Xtro\slc38a10, Xtro\slc38a7" "Mmus\Slc38a2, Mmus\Slc38a1, Mmus\Slc38a10, Mmus\Slc38a3, Mmus\Slc38a4, Mmus\Slc38a9, Mmus\Slc38a5, Mmus\Slc38a6, Mmus\Slc38a7, Mmus\Slc38a8, Mmus\Slc38a11" "Hsap\SLC38A5, Hsap\SLC38A2, Hsap\SLC38A11, Hsap\SLC38A10, Hsap\SLC38A7, Hsap\SLC38A9, Hsap\SLC38A6, Hsap\SLC38A1, Hsap\SLC38A4, Hsap\SLC38A8" viable FBgn0015033 Cyp4d8 Cytochrome P450-4d8 http://flybase.org/reports/FBgn0015033 - protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4d8, P450, P-450, CG4321, Cyp4d8, CYP4d8" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG4321 11-Aug-17 DroID_v2017_08 "Drer\cyp26b1, Drer\cyp4t8, Drer\cyp19a1b, Drer\cyp26a1, Drer\cyp20a1, Drer\cyp46a1.4, Drer\cyp4v8, Drer\cyp26c1, Drer\tbxas1, Drer\cyp46a1.2, Drer\cyp46a1.1, Drer\LOC100329425, Drer\cyp46a1.3, Drer\cyp4f3, Drer\cyp4v7, Drer\cyp19a1a" "Scer\DIT2, Scer\ERG5" "Cele\cyp-29A4, Cele\cyp-32A1, Cele\cyp-31A3, Cele\cyp-25A1, Cele\cyp-29A3, Cele\cyp-29A2, Cele\cyp-13A6, Cele\cyp-37B1, Cele\cyp-31A5, Cele\cyp-37A1, Cele\cyp-42A1, Cele\cyp-13A2, Cele\cyp-13A1, Cele\cyp-31A2, Cele\cyp-13A7, Cele\cyp-32B1" "Xtro\cyp4v2, Xtro\mgc108213, Xtro\cyp4b1, Xtro\cyp26b1, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\LOC100488227, Xtro\cyp19a1, Xtro\LOC100487918, Xtro\cyp4f2, Xtro\cyp4f22, Xtro\cyp26a1, Xtro\cyp20a1" "Mmus\Cyp26a1, Mmus\Cyp3a41b, Mmus\Cyp26c1, Mmus\Cyp4a30b, Mmus\Cyp4f18, Mmus\Cyp4f40, Mmus\Cyp4v3, Mmus\Cyp4a10, Mmus\Cyp4f14, Mmus\Cyp20a1, Mmus\Cyp4b1, Mmus\Cyp4f37, Mmus\Cyp4a29, Mmus\Cyp26b1, Mmus\Cyp46a1, Mmus\Cyp4f15, Mmus\Cyp4a14, Mmus\Cyp3a11, Mmus\Cyp3a13, Mmus\Cyp4f17, Mmus\Cyp4f39, Mmus\Cyp4f16, Mmus\Cyp19a1, Mmus\Cyp4x1, Mmus\Cyp4f13, Mmus\Cyp4a31, Mmus\Cyp4a32, Mmus\Cyp4a12a, Mmus\Tbxas1, Mmus\Cyp3a44, Mmus\Cyp4a12b" "Hsap\CYP4A11, Hsap\CYP4F8, Hsap\CYP4F2, Hsap\CYP3A4, Hsap\CYP4F11, Hsap\CYP4V2, Hsap\CYP4F3, Hsap\CYP26A1, Hsap\CYP26B1, Hsap\CYP4X1, Hsap\CYP20A1, Hsap\CYP26C1, Hsap\CYP4A22, Hsap\TBXAS1, Hsap\CYP46A1, Hsap\CYP19A1, Hsap\CYP4F12, Hsap\CYP4B1, Hsap\CYP4F22, Hsap\CYP4Z1" viable FBgn0031974 CG12560 - http://flybase.org/reports/FBgn0031974 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 histone acetylation ; GO:0016573 | inferred from mutant phenotype - CG12560 "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG12560 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-106k19.2, Drer\si:dkey-76k16.5, Drer\si:dkey-76k16.6" - "Cele\ZK185.3, Cele\T10B10.4" - "Mmus\Keg1, Mmus\Glyat, Mmus\Gm4952, Mmus\Glyatl3" "Hsap\GLYATL1, Hsap\GLYAT, Hsap\GLYATL3, Hsap\GLYATL2" viable FBgn0265140 Meltrin Meltrin http://flybase.org/reports/FBgn0265140 protein_coding_gene identical protein binding ; GO:0042802 | inferred from physical interaction with Meltrin metalloendopeptidase activity ; GO:0004222 | inferred from direct assay protein oligomerization ; GO:0051259 | inferred from direct assay membrane protein ectodomain proteolysis ; GO:0006509 | inferred from direct assay membrane protein ectodomain proteolysis ; GO:0006509 | inferred from sequence or structural similarity with HGNC:195 perivitelline space ; GO:0098595 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:195 "CG7649, Meltrin, Neu3, CG31314, CG31385, DMeltrin, CT23341, meltrin, FBgn0051314" "IPR034027:Reprolysin domain, adamalysin-type, IPR000742:EGF-like domain, IPR001590:Peptidase M12B, ADAM/reprolysin, IPR001762:Disintegrin domain, IPR002870:Peptidase M12B, propeptide, IPR006586:ADAM, cysteine-rich, IPR013032:EGF-like, conserved site, IPR024079:Metallopeptidase, catalytic domain" CG7649 11-Aug-17 DroID_v2017_08 "Drer\adam12, Drer\adam23a, Drer\adam8a, Drer\adam17a, Drer\adam19a, Drer\adam15, Drer\zgc:174164, Drer\adam8b, Drer\adam11, Drer\adam22, Drer\adam17b, Drer\adam28, Drer\adam19b, Drer\adam9" - "Cele\tag-275, Cele\K08B4.2, Cele\unc-71, Cele\adm-2, Cele\F27D9.7, Cele\adm-4" "Xtro\adam23, Xtro\adam33, Xtro\adam11, Xtro\adam19, Xtro\adam9, Xtro\adam12" "Mmus\Adam1b, Mmus\Adamdec1, Mmus\Adam39, Mmus\Adam22, Mmus\Adam34, Mmus\Adam6a, Mmus\Adam1a, Mmus\Adam30, Mmus\Adam24, Mmus\Adam32, Mmus\Adam26a, Mmus\Adam19, Mmus\Adam25, Mmus\Adam7, Mmus\Adam18, Mmus\Adam4, Mmus\Gm4787, Mmus\Adam23, Mmus\Adam5, Mmus\Adam9, Mmus\Gm5346, Mmus\Adam21, Mmus\Adam6b, Mmus\Adam2, Mmus\Adam8, Mmus\Adam11, Mmus\Adam33, Mmus\Adam17, Mmus\Adam12, Mmus\Adam28, Mmus\Adam29, Mmus\Adam3, Mmus\Adam26b, Mmus\Adam20, Mmus\Adam15" "Hsap\ADAM18, Hsap\ADAM30, Hsap\ADAM29, Hsap\ADAM23, Hsap\ADAM20, Hsap\ADAM21, Hsap\ADAM28, Hsap\ADAM32, Hsap\ADAM7, Hsap\ADAM15, Hsap\ADAMDEC1, Hsap\ADAM11, Hsap\ADAM2, Hsap\ADAM8, Hsap\ADAM9, Hsap\ADAM17, Hsap\ADAM33, Hsap\ADAM22, Hsap\ADAM19, Hsap\ADAM12" embryonic stage | blastoderm ventral ectoderm anlage

FBgn0033830 CG10814 - http://flybase.org/reports/FBgn0033830 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003819 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003819 sleep ; GO:0030431 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available CG10814 "IPR003819:TauD/TfdA-like domain, IPR010376:Domain of unknown function DUF971" CG10814 11-Aug-17 DroID_v2017_08 "Drer\tmlhe, Drer\bbox1" Scer\AIM17 "Cele\gbh-1, Cele\gbh-2" "Xtro\bbox1, Xtro\tmlhe" "Mmus\Bbox1, Mmus\Tmlhe" Hsap\BBOX1 viable FBgn0002626 RpL32 Ribosomal protein L32 http://flybase.org/reports/FBgn0002626 "FBgn0010264, FBgn0047051" protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001515, InterPro:IPR018263 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001515, InterPro:IPR018263 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001515, InterPro:IPR018263 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement nucleolus ; GO:0005730 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay" "RpL32, M(3)99D, 143250_at, Rp-49, RP-49, rp49, L32, Rp49, RP49, bs30a02.y1, Rp49/RpL32, CG7939, BcDNA:RH03940, Rpl32, RPL32, rp49/RpL32, rpl32" "IPR018263:Ribosomal protein L32e, conserved site, IPR001515:Ribosomal protein L32e" CG7939 11-Aug-17 DroID_v2017_08 Drer\rpl32 Scer\RPL32 Cele\rpl-32 "Xtro\LOC100493057, Xtro\rpl32" "Mmus\Rpl32l, Mmus\Rpl32" Hsap\RPL32 wild-type DRSC16835 EK 1.098929632 0.638110286 3.270627075 -3.967281525 1.764939837 2.840864331 FBgn0024996 eIF2Bbeta eukaryotic translation initiation factor 2B subunit beta http://flybase.org/reports/FBgn0024996 - protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000004282 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD:S000004282 translational initiation ; GO:0006413 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000027918 eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity with SGD:S000004282 "EG:100G10.3, CG2677, eIF2Bbeta, DMC100G10.3, eIF2B-beta, EIF2b" IPR000649:Initiation factor 2B-related CG2677 11-Aug-17 DroID_v2017_08 Drer\eif2b2 Scer\GCD7 Cele\Y47H9C.7 Xtro\eif2b2 Mmus\Eif2b2 Hsap\EIF2B2 "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0037802 Sirt6 Sirtuin 6 http://flybase.org/reports/FBgn0037802 protein_coding_gene NAD+ binding ; GO:0070403 | inferred from electronic annotation with InterPro:IPR003000 histone deacetylase activity ; GO:0004407 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from mutant phenotype histone deacetylation ; GO:0016575 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:14934 "dmSRT408, CG6284, dSIRT6, D.mel4, Sirt6" "IPR003000:Sirtuin family, IPR029035:DHS-like NAD/FAD-binding domain, IPR026590:Sirtuin family, catalytic core domain" CG6284 11-Aug-17 DroID_v2017_08 "Drer\sirt6, Drer\sirt7, Drer\rpl17" - "Cele\sir-2.4, Cele\rpl-17" "Xtro\rpl17, Xtro\sirt7, Xtro\sirt6" "Mmus\Rpl17, Mmus\Sirt6, Mmus\Sirt7" "Hsap\RPL17, Hsap\SIRT6, Hsap\C18orf32, Hsap\SIRT7, Hsap\RPL17-C18orf32" "short lived,viable" FBgn0031359 Rim2 Replication in mitochondria 2 http://flybase.org/reports/FBgn0031359 protein_coding_gene pyrimidine nucleotide transmembrane transporter activity ; GO:0015218 | inferred from biological aspect of ancestor with PANTHER:PTN000642030 cellular respiration ; GO:0045333 | inferred from mutant phenotype deoxynucleotide transport ; GO:0030302 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype mitochondrion distribution ; GO:0048311 | inferred from mutant phenotype mitochondrial pyrimidine nucleotide import ; GO:1990519 | inferred from biological aspect of ancestor with PANTHER:PTN000642030 locomotion ; GO:0040011 | inferred from mutant phenotype transcription from mitochondrial promoter ; GO:0006390 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG18317, Rim2, drim2" "IPR002030:Mitochondrial brown fat uncoupling protein, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG18317 11-Aug-17 DroID_v2017_08 "Drer\slc25a36b, Drer\slc25a36a, Drer\slc25a33" "Scer\YIA6, Scer\RIM2" Cele\T09F3.2 Xtro\slc25a36 "Mmus\Slc25a33, Mmus\Slc25a36" "Hsap\SLC25A33, Hsap\SLC25A36" "viable,long lived" FBgn0031868 Rat1 Rat1 5'-3' exoribonuclease http://flybase.org/reports/FBgn0031868 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004859 5'-3' exonuclease activity ; GO:0008409 | inferred from sequence or structural similarity with UniProtKB:Q9H0D6 "DNA catabolic process, exonucleolytic ; GO:0000738 | inferred from sequence or structural similarity with UniProtKB:Q9H0D6 neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "RAT1, dhp1, CG10354, Rat1, XRN2, dRAT1, Xrn2" "IPR004859:Putative 5-3 exonuclease, IPR027073:5'-3' exoribonuclease" CG10354 11-Aug-17 DroID_v2017_08 "Drer\xrn1, Drer\xrn2" "Scer\RAT1, Scer\XRN1" "Cele\xrn-2, Cele\xrn-1" "Xtro\xrn1, Xtro\xrn2" "Mmus\Xrn1, Mmus\Xrn2" "Hsap\XRN1, Hsap\XRN2" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0038360 CG9590 - http://flybase.org/reports/FBgn0038360 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2 - Golgi cis cisterna ; GO:0000137 | inferred from direct assay CG9590 IPR007998:Protein of unknown function DUF719 CG9590 11-Aug-17 DroID_v2017_08 "Drer\fam114a1, Drer\fam114a2" - - "Xtro\fam114a1, Xtro\fam114a2" "Mmus\Fam114a2, Mmus\Fam114a1" "Hsap\FAM114A2, Hsap\FAM114A1" viable FBgn0015032 Cyp4c3 Cytochrome P450-4c3 http://flybase.org/reports/FBgn0015032 - protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CG1438, 4C3, P450, P-450, Cyp4c3, cyp4c3" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG1438 11-Aug-17 DroID_v2017_08 "Drer\cyp20a1, Drer\cyp46a1.3, Drer\cyp3c2, Drer\cyp26a1, Drer\cyp46a1.2, Drer\cyp19a1a, Drer\cyp46a1.1, Drer\cyp3c4, Drer\cyp26b1, Drer\cyp4f3, Drer\cyp3a65, Drer\cyp4v7, Drer\cyp3c3, Drer\cyp4v8, Drer\cyp3c1, Drer\cyp19a1b, Drer\LOC100329425, Drer\cyp46a1.4, Drer\cyp26c1, Drer\cyp4t8" "Scer\ERG5, Scer\DIT2" "Cele\cyp-42A1, Cele\cyp-37B1, Cele\cyp-13A10, Cele\cyp-32A1, Cele\cyp-25A1, Cele\cyp-31A5, Cele\cyp-37A1, Cele\cyp-13A5, Cele\cyp-25A2, Cele\cyp-31A3, Cele\cyp-13A4, Cele\cyp-13A7, Cele\cyp-31A2, Cele\cyp-25A4, Cele\cyp-13A12, Cele\cyp-13A8, Cele\cyp-29A2, Cele\cyp-13A3, Cele\cyp-13A1, Cele\cyp-25A3, Cele\cyp-29A4, Cele\cyp-13A11, Cele\cyp-32B1, Cele\cyp-29A3" "Xtro\cyp4f22, Xtro\cyp26a1, Xtro\cyp19a1, Xtro\LOC100488227, Xtro\LOC100487918, Xtro\cyp26b1, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\mgc108213, Xtro\LOC100485929, Xtro\cyp4v2, Xtro\cyp20a1, Xtro\cyp4f2, Xtro\cyp4b1" "Mmus\Cyp4f14, Mmus\Cyp3a11, Mmus\Cyp4a12b, Mmus\Cyp4f40, Mmus\Cyp20a1, Mmus\Cyp26a1, Mmus\Cyp4f39, Mmus\Cyp3a41a, Mmus\Cyp4a32, Mmus\Cyp3a16, Mmus\Cyp4f13, Mmus\Cyp3a25, Mmus\Cyp3a13, Mmus\Cyp3a44, Mmus\Cyp3a41b, Mmus\Cyp4a29, Mmus\Cyp4f17, Mmus\Cyp4a10, Mmus\Cyp4b1, Mmus\Cyp4f37, Mmus\Cyp4f15, Mmus\Cyp26c1, Mmus\Cyp4a12a, Mmus\Cyp46a1, Mmus\Cyp4a31, Mmus\Cyp4a30b, Mmus\Cyp19a1, Mmus\Cyp3a59, Mmus\Cyp4a14, Mmus\Cyp4f18, Mmus\Klkb1, Mmus\Cyp4x1, Mmus\Cyp4v3, Mmus\Cyp26b1, Mmus\Cyp3a57, Mmus\Cyp4f16" "Hsap\CYP26C1, Hsap\CYP4F12, Hsap\CYP4X1, Hsap\CYP3A7, Hsap\CYP4B1, Hsap\CYP4A11, Hsap\CYP3A4, Hsap\CYP4V2, Hsap\CYP19A1, Hsap\CYP46A1, Hsap\CYP4Z1, Hsap\CYP3A5, Hsap\CYP26B1, Hsap\CYP4F8, Hsap\CYP3A43, Hsap\CYP4A22, Hsap\CYP4F11, Hsap\CYP4F22, Hsap\CYP4F3, Hsap\CYP20A1, Hsap\CYP26A1, Hsap\CYP4F2" viable FBgn0030588 CG9521 - http://flybase.org/reports/FBgn0030588 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG9521, Dm GMCtheta2" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9521 11-Aug-17 DroID_v2017_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH "lethal,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015381 dsf dissatisfaction http://flybase.org/reports/FBgn0015381 - protein_coding_gene "RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | inferred from electronic annotation with InterPro:IPR003068 steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay steroid hormone receptor activity ; GO:0003707 | non-traceable author statement transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | traceable author statement" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 regulation of female receptivity ; GO:0045924 | non-traceable author statement sex determination ; GO:0007530 | traceable author statement regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype copulation ; GO:0007620 | non-traceable author statement courtship behavior ; GO:0007619 | traceable author statement somatic sex determination ; GO:0018993 | non-traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:1100526 mating behavior ; GO:0007617 | non-traceable author statement oviposition ; GO:0018991 | non-traceable author statement oviposition ; GO:0018991 | traceable author statement courtship behavior ; GO:0007619 | non-traceable author statement male courtship behavior ; GO:0008049 | traceable author statement mating behavior, sex discrimination ; GO:0048047 | traceable author statement" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR003068" "dissatisfaction, DSF, CG9019, dsf, NR2E4, Dsf" "IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR003068:Transcription factor COUP, IPR013088:Zinc finger, NHR/GATA-type" CG9019 11-Aug-17 DroID_v2017_08 "Drer\nr6a1b, Drer\rxrga, Drer\rxrbb, Drer\esr2b, Drer\nr1h4, Drer\nr0b2b, Drer\nr2c2, Drer\nr2f5, Drer\pgr, Drer\nr2e3, Drer\nr1i2, Drer\pparda, Drer\thrab, Drer\nr2f6b, Drer\rxrba, Drer\esrrga, Drer\ppardb, Drer\vdrb, Drer\vdra, Drer\rarab, Drer\nr2f1b, Drer\pparaa, Drer\nr2f2, Drer\nr2f1a, Drer\nr2e1, Drer\esrra, Drer\rxraa, Drer\raraa, Drer\nr3c1, Drer\rargb, Drer\esrrd, Drer\pparg, Drer\pparab, Drer\ar, Drer\nr2c1, Drer\nr1h5, Drer\esr1, Drer\nr5a1a, Drer\esr2a, Drer\nr0b2a, Drer\rxrab, Drer\nr2f6a, Drer\nr0b1" - "Cele\nhr-41, Cele\nhr-67, Cele\nhr-236, Cele\fax-1" "Xtro\thrb, Xtro\nr2c1, Xtro\rarb, Xtro\nr2c2, Xtro\nr1h5, Xtro\esrra, Xtro\pparg, Xtro\rxrg, Xtro\rarg, Xtro\ppara, Xtro\esr1, Xtro\pgr, Xtro\nr2f5, Xtro\nr3c1, Xtro\rxra, Xtro\rxrb, Xtro\nr1i2, Xtro\esrrg, Xtro\ar, Xtro\ppard, Xtro\nr2f1, Xtro\nr0b2, Xtro\esrrb, Xtro\nr2e3, Xtro\nr2f2, Xtro\esrrgr, Xtro\nr3c2, Xtro\vdr, Xtro\nr2f6, Xtro\nr1h2, Xtro\nr6a1, Xtro\rara, Xtro\nr0b1, Xtro\nr2e1, Xtro\esr2" "Mmus\Rara, Mmus\Nr1h4, Mmus\Rxra, Mmus\Nr6a1, Mmus\Nr0b2, Mmus\Esrra, Mmus\Nr1h5, Mmus\Rxrg, Mmus\Nr2e1, Mmus\Nr2e3, Mmus\Thra, Mmus\Rxrb, Mmus\Ar, Mmus\Thrb, Mmus\Pgr, Mmus\Nr2f2, Mmus\Rarb, Mmus\Nr1i3, Mmus\Nr2f1, Mmus\Pparg, Mmus\Nr3c1, Mmus\Ppard, Mmus\Esrrb, Mmus\Nr2c2, Mmus\Rarg, Mmus\Nr2c1, Mmus\Ppara, Mmus\Nr1h2, Mmus\Vdr, Mmus\Nr0b1, Mmus\Nr2f6, Mmus\Nr1i2, Mmus\Esr1, Mmus\Nr3c2, Mmus\Nr1h3, Mmus\Esrrg, Mmus\Esr2" "Hsap\RARB, Hsap\NR1I3, Hsap\PPARG, Hsap\NR2E1, Hsap\NR1H2, Hsap\THRB, Hsap\PGR, Hsap\NR3C1, Hsap\NR2F1, Hsap\RXRA, Hsap\NR2C1, Hsap\VDR, Hsap\ESRRG, Hsap\PPARA, Hsap\NR2C2, Hsap\NR0B2, Hsap\RXRB, Hsap\THRA, Hsap\NR6A1, Hsap\NR3C2, Hsap\NR1I2, Hsap\RARA, Hsap\AR, Hsap\NR2F2, Hsap\ESRRB, Hsap\NR2F6, Hsap\ESR1, Hsap\NR0B1, Hsap\PPARD, Hsap\ESR2, Hsap\RARG, Hsap\NR1H4, Hsap\ESRRA, Hsap\RXRG, Hsap\NR1H3, Hsap\NR2E3" " larval stage , embryonic stage -- adult stage , pupal stage , pharate adult stage " " larval brain | anterior | restricted

, anterior protocerebral neuromere | restricted

, adult brain | restricted

, embryonic/larval salivary gland

" "mating defective,neuroanatomy defective,behavior defective,male limited,male,recessive,courtship behavior defective,female,partially lethal - majority die,visible,melanotic necrosis,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,viable,fertile,lethal - all die before end of larval stage,some die during larval stage,wild-type" "adult abdominal segment 5 & synapse | malecl7),leg,distal,eye,ommatidium,interommatidial bristle,pigment cell,ectopic,third segment of antenna,pupa,posterior,arista,wing,mesothoracic tergum,tarsal segment,metathoracic leg" DRSC03524 IK -0.466395363 -1.996815698 -0.778496291 0.108042246 1.447215464 1.571732593 FBgn0031344 CG7420 - http://flybase.org/reports/FBgn0031344 protein_coding_gene - - - CG7420 "IPR000408:Regulator of chromosome condensation, RCC1, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG7420 11-Aug-17 DroID_v2017_08 "Drer\herc1, Drer\ftr97, Drer\als2b, Drer\rcc2, Drer\rpgrb, Drer\als2a, Drer\rccd1, Drer\sergef, Drer\rcbtb2, Drer\wbscr16, Drer\rpgra, Drer\herc2, Drer\rcbtb1, Drer\rcc1" "Scer\SRM1, Scer\FMP25, Scer\ATS1" "Cele\glo-4, Cele\W09G3.7" "Xtro\rcbtb2, Xtro\rcbtb1, Xtro\als2, Xtro\wbscr16, Xtro\sergef, Xtro\herc1, Xtro\nek9, Xtro\rcc1, Xtro\herc2, Xtro\als2cl" "Mmus\Herc1, Mmus\Rcbtb1, Mmus\Rcc1, Mmus\Gm15800, Mmus\Rpgr, Mmus\Herc2, Mmus\Rcbtb2, Mmus\Sergef, Mmus\Wbscr16, Mmus\Als2, Mmus\Nek9, Mmus\Rcc2, Mmus\Rccd1" "Hsap\RCC1, Hsap\HERC2, Hsap\RCBTB1, Hsap\RCBTB2, Hsap\ALS2, Hsap\RCCD1, Hsap\HERC4, Hsap\RCC1L, Hsap\RPGR, Hsap\SERGEF, Hsap\RCC2, Hsap\HERC1, Hsap\NEK9, Hsap\HECTD4" "viable,fertile" FBgn0086605 CG9853 - http://flybase.org/reports/FBgn0086605 protein_coding_gene - protein insertion into ER membrane ; GO:0045048 | inferred from biological aspect of ancestor with PANTHER:PTN000305707 BAT3 complex ; GO:0071818 | inferred from biological aspect of ancestor with PANTHER:PTN000305707 "BEST:LD21829, CG9853, CG41469" IPR007317:Uncharacterised protein family UPF0363 CG9853 11-Aug-17 DroID_v2017_08 Drer\get4 Scer\GET4 Cele\cee-1 Xtro\get4 Mmus\Get4 Hsap\GET4 FBgn0016687 Nurf-38 Nucleosome remodeling factor - 38kD http://flybase.org/reports/FBgn0016687 FBgn0021828 protein_coding_gene magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR008162 inorganic diphosphatase activity ; GO:0004427 | non-traceable author statement inorganic diphosphatase activity ; GO:0004427 | inferred from direct assay nucleosome-dependent ATPase activity ; GO:0070615 | contributes_to inferred by curator from GO:0016589 "phosphate-containing compound metabolic process ; GO:0006796 | inferred from electronic annotation with InterPro:IPR008162 chromatin remodeling ; GO:0006338 | inferred from direct assay positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with N nucleosome mobilization ; GO:0042766 | inferred from direct assay transcription, DNA-templated ; GO:0006351 | inferred from direct assay regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from genetic interaction with EcR" NURF complex ; GO:0016589 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay NURF complex ; GO:0016589 | traceable author statement NURF complex ; GO:0016589 | inferred from direct assay inferred from physical interaction with Iswi inferred from physical interaction with Caf1-55 cytoplasm ; GO:0005737 | inferred from direct assay "NURF38, NURF, Nurf38, CG4634, p38, 38, p38/NURF-38, NURF-38, dNURF, l(2)k16102, Nurf-38, N38, Nurf 38, NURF 38" IPR008162:Inorganic pyrophosphatase CG4634 11-Aug-17 DroID_v2017_08 "Drer\ppa1b, Drer\ppa1a, Drer\sar1ab, Drer\ppa2, Drer\sar1b" "Scer\IPP1, Scer\PPA2" "Cele\sar-1, Cele\pyp-1" "Xtro\ppa1, Xtro\ppa2, Xtro\sar1a" "Mmus\Ppa1, Mmus\Ppa2, Mmus\Sar1b, Mmus\Sar1a" "Hsap\SAR1B, Hsap\PPA2, Hsap\SAR1A, Hsap\PPA1" "lethal,recessive,female semi-sterile,female fertile" DRSC26858 K 0.452209491 -0.118875599 -0.793648108 0.276111151 -1.511973324 -0.405770392 FBgn0031081 Nep3 Neprilysin 3 http://flybase.org/reports/FBgn0031081 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497 metallopeptidase activity ; GO:0008237 | inferred from sequence model" detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model peptide hormone processing ; GO:0016486 | inferred from sequence or structural similarity with HGNC:13275 integral component of membrane ; GO:0016021 | inferred from sequence model "dNEP3, CEC, CG9565, Nep3, DmeNEP3, NEP3, nep3" "IPR018497:Peptidase M13, C-terminal domain, IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR029733:Endothelin-converting enzyme 2" CG9565 11-Aug-17 DroID_v2017_08 "Drer\mmel1, Drer\ece1, Drer\ece2b, Drer\phex, Drer\kel" - "Cele\nep-26, Cele\nep-21, Cele\nep-11, Cele\nep-2, Cele\nep-12, Cele\nep-1, Cele\nep-22, Cele\nep-17" "Xtro\mmel1, Xtro\ece2, Xtro\ecel1, Xtro\ece1" "Mmus\Mme, Mmus\Ecel1, Mmus\Kel, Mmus\Ece1, Mmus\Ece2, Mmus\Mmel1, Mmus\Phex" "Hsap\ECEL1, Hsap\MMEL1, Hsap\PHEX, Hsap\ECE2, Hsap\MME, Hsap\ECE1, Hsap\KEL" viable FBgn0002031 l(2)37Cc lethal (2) 37Cc http://flybase.org/reports/FBgn0002031 FBgn0032758 protein_coding_gene - cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000163 microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG10691, l(2)37Cc, Cc, l(2)Cc, fs(2)HH32, l (2) 37Cc" "IPR000163:Prohibitin, IPR001107:Band 7 domain" CG10691 11-Aug-17 DroID_v2017_08 "Drer\phb2a, Drer\phb2b, Drer\phb" Scer\PHB1 "Cele\phb-2, Cele\phb-1" "Xtro\phb2, Xtro\phb" "Mmus\Phb2, Mmus\Phb" "Hsap\PHB, Hsap\PHB2" embryonic stage&&larval stage&&adult stage "female sterile,partially lethal - majority die,recessive,cold sensitive,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,heat sensitive,visible,male sterile,body color defective,dominant,some die during pupal stage" "egg,wing,macrochaeta,melanotic mass & adult abdomen,egg chamber,cystocyte,yolk,trichogen cell,mesothoracic tergum" DRSC03563 K -1.497571604 -0.474289239 -1.325147187 -1.419442079 1.561792802 -0.182566357 FBgn0033373 CG8080 - http://flybase.org/reports/FBgn0033373 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from sequence or structural similarity with HGNC:26404 NADP biosynthetic process ; GO:0006741 | inferred from electronic annotation with InterPro:IPR002504 NAD metabolic process ; GO:0019674 | inferred from sequence or structural similarity with HGNC:26404 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:26404 "CG30346, CG8080" "IPR002504:NAD kinase, IPR012355:NAD kinase, eukaryotic, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR017437:ATP-NAD kinase, PpnK-type, all-beta, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG8080 11-Aug-17 DroID_v2017_08 Drer\nadk2 - "Cele\Y17G7B.10, Cele\Y77E11A.2" Xtro\nadk2 Mmus\Nadk2 Hsap\NADK2 "viable,visible" trichogen cell FBgn0053837 His1:CG33837 His1:CG33837 http://flybase.org/reports/FBgn0053837 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33837, His1:CG33837" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33837 11-Aug-17 DroID_v2017_08 "Drer\h1f0, Drer\zgc:110216, Drer\si:dkey-108k21.10, Drer\si:dkey-108k21.14, Drer\zgc:163061, Drer\zgc:153405, Drer\h1fx, Drer\si:ch211-113a14.24, Drer\histh1l, Drer\si:dkey-108k21.21, Drer\si:ch1073-159d7.7, Drer\zgc:110425, Drer\h1m, Drer\si:ch73-36p18.1, Drer\si:dkey-261m9.12" Scer\HHO1 "Cele\hil-2, Cele\hil-6, Cele\hil-4, Cele\his-24, Cele\hil-1, Cele\hil-5, Cele\hil-3" - "Mmus\Hist1h1c, Mmus\H1foo, Mmus\Hist1h1b, Mmus\Hist1h1e, Mmus\Hils1, Mmus\Hist1h1a, Mmus\Hist1h1t, Mmus\H1fnt, Mmus\H1fx, Mmus\Hist1h1d" "Hsap\HIST1H1A, Hsap\HIST1H1D, Hsap\H1FOO, Hsap\HIST1H1T, Hsap\HIST1H1C, Hsap\H1F0, Hsap\H1FNT, Hsap\HIST1H1E, Hsap\H1FX, Hsap\HIST1H1B" FBgn0015283 Rpn10 Regulatory particle non-ATPase 10 http://flybase.org/reports/FBgn0015283 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from direct assay polyubiquitin binding ; GO:0031593 | inferred from sequence or structural similarity with SGD:S000001243 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with Ubc4 polyubiquitin binding ; GO:0031593 | inferred from biological aspect of ancestor with PANTHER:PTN000027362 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype inferred from genetic interaction with Ube3a proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome assembly ; GO:0043248 | inferred from biological aspect of ancestor with PANTHER:PTN000027362 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype "cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000027362 proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000001243 nucleus ; GO:0005634 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9561 inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from biological aspect of ancestor with PANTHER:PTN000027362 cytoplasm ; GO:0005737 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay" "S5A, p54, dRpn10, S5a, mu-54, CG7619, Rpn10, DmS5a, Rpn10/p54, 7619, Pros54, pros54" "IPR002035:von Willebrand factor, type A, IPR003903:Ubiquitin interacting motif, IPR027040:Proteasome subunit Rpn10" CG7619 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-243a15.1, Drer\pip5k1bb, Drer\pip5k1ba, Drer\psmd4b, Drer\psmd4a, Drer\pip5k1ab, Drer\pip5k1aa" Scer\RPN10 "Cele\rpn-10, Cele\ppk-1" "Xtro\pip5k1c, Xtro\pip5k1b, Xtro\pip5k1a, Xtro\psmd4" "Mmus\Pip5k1b, Mmus\Psmd4, Mmus\Pip5k1c, Mmus\Pip5k1a" "Hsap\PIP5K1A, Hsap\PIP5K1C, Hsap\PIP5K1B, Hsap\PSMD4" "viable,fertile,lethal - all die before end of larval stage,some die during larval stage,some die during third instar larval stage,lethal,partially lethal - majority die,developmental rate defective,mitotic cell cycle defective" "embryonic/larval brain,pupal cuticle,nuclear chromosome | larval stage,condensed nuclear chromosome | larval stage,ventral nerve cord" DRSC11876 IK -1.10666165 -2.047158155 -1.111297765 -1.101010214 2.921975387 0.034796142 FBgn0032451 spict spichthyin http://flybase.org/reports/FBgn0032451 protein_coding_gene magnesium ion transmembrane transporter activity ; GO:0015095 | inferred from electronic annotation with InterPro:IPR008521 negative regulation of BMP signaling pathway ; GO:0030514 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype magnesium ion transport ; GO:0015693 | inferred from biological aspect of ancestor with PANTHER:PTN001758175 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008521 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001758175 "CG12292, spict, spg6, Spict" IPR008521:Magnesium transporter NIPA CG12292 11-Aug-17 DroID_v2017_08 "Drer\nipal3, Drer\nipal4, Drer\nipa1, Drer\nipa2, Drer\zgc:101583" - Cele\nipa-1 "Xtro\MGC108429, Xtro\nipal3, Xtro\nipal1, Xtro\nipal4, Xtro\nipa2" "Mmus\Nipal2, Mmus\Nipal4, Mmus\Nipal1, Mmus\Nipa1, Mmus\Nipal3, Mmus\Nipa2" "Hsap\NIPAL3, Hsap\NIPAL2, Hsap\NIPA1, Hsap\NIPA2, Hsap\NIPAL1, Hsap\NIPAL4" "viable,fertile,developmental rate defective,neuroanatomy defective" "embryonic/larval neuromuscular junction,bouton,supernumerary,posterior crossvein,wing,type I bouton" FBgn0024992 CG2658 - http://flybase.org/reports/FBgn0024992 FBgn0015870 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000642, InterPro:IPR005936, InterPro:IPR011546 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000642, InterPro:IPR003959, InterPro:IPR011546 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011546 metallopeptidase activity ; GO:0008237 | inferred from sequence or structural similarity with UniProtKB:Q9UQ90 ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with UniProtKB:Q9UQ90" proteolysis ; GO:0006508 | inferred from sequence or structural similarity with UniProtKB:Q9UQ90 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011546 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9UQ90 "Dm100G10.aj, anon-3Ba, EG:100G10.7, CG2658" "IPR000642:Peptidase M41, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR005936:Peptidase, FtsH, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011546:Peptidase M41, FtsH extracellular" CG2658 11-Aug-17 DroID_v2017_08 "Drer\spg7, Drer\afg3l2, Drer\yme1l1a" "Scer\AFG3, Scer\YTA12, Scer\YME1" "Cele\ymel-1, Cele\spg-7, Cele\Y47C4A.1, Cele\ppgn-1, Cele\Y108F1.1" "Xtro\spg7, Xtro\afg3l1p" "Mmus\Spg7, Mmus\Afg3l2, Mmus\Yme1l1, Mmus\Afg3l1" "Hsap\YME1L1, Hsap\SPG7, Hsap\AFG3L2" "viable,fertile" FBgn0037754 CG8500 - http://flybase.org/reports/FBgn0037754 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with MGI:MGI:97852" small GTPase mediated signal transduction ; GO:0007264 | inferred from sequence or structural similarity with MGI:MGI:97852 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available "CG8500, Q9VH66" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG8500 11-Aug-17 DroID_v2017_08 "Drer\kras, Drer\mras, Drer\si:dkey-27j5.5, Drer\rap2b, Drer\rap1ab, Drer\zgc:110699, Drer\LOC100332969, Drer\diras2, Drer\rem2, Drer\rasl11a, Drer\si:ch73-116o1.2, Drer\rap1aa, Drer\rsg1, Drer\rem1, Drer\nras, Drer\rrad, Drer\gem, Drer\rasl12, Drer\rasd1, Drer\ralaa, Drer\si:dkeyp-59c12.1, Drer\rhebl1, Drer\diras1b, Drer\rheb, Drer\rit1, Drer\hrasb, Drer\ralba, Drer\rras2, Drer\rasl10a, Drer\rap2c, Drer\ralbb, Drer\diras1a, Drer\rap2ab, Drer\zgc:152698, Drer\rasl11b, Drer\hrasa, Drer\rerglb, Drer\zgc:153845, Drer\zgc:114118, Drer\rergla, Drer\ralab, Drer\rras, Drer\zgc:171704, Drer\zgc:64022" "Scer\RAS2, Scer\RHB1, Scer\RSR1, Scer\RAS1" Cele\drn-1 "Xtro\kras, Xtro\rap2a, Xtro\rasl10a, Xtro\rasd1, Xtro\rhebl1, Xtro\rem1, Xtro\rap1b, Xtro\rergl, Xtro\gem, Xtro\rap2b, Xtro\diras1, Xtro\rap2c, Xtro\rap1a, Xtro\rala, Xtro\rasl11b, Xtro\rasd2, Xtro\rrad, Xtro\diras3, Xtro\rsg1, Xtro\ralb, Xtro\diras2, Xtro\rheb, Xtro\LOC733456, Xtro\rerg, Xtro\rem2, Xtro\nras, Xtro\rit1, Xtro\hras, Xtro\ras-dva" "Mmus\Rasd2, Mmus\Rap1b, Mmus\Eras, Mmus\Rala, Mmus\Rap2c, Mmus\Kras, Mmus\Rap2b, Mmus\Rasl12, Mmus\Rasl10b, Mmus\Rras2, Mmus\Ralb, Mmus\Rras, Mmus\Mras, Mmus\Rasl10a, Mmus\Rerg, Mmus\Nras, Mmus\Rasl11a, Mmus\Rsg1, Mmus\Rit2, Mmus\Rrad, Mmus\Gem, Mmus\Rasl11b, Mmus\Rhebl1, Mmus\Rap1a, Mmus\Gm266, Mmus\Rheb, Mmus\Rem1, Mmus\Rem2, Mmus\Rit1, Mmus\Rergl, Mmus\Rap2a, Mmus\Diras2, Mmus\Rasd1, Mmus\Hras, Mmus\Diras1" "Hsap\RASL11B, Hsap\RASL10A, Hsap\RIT2, Hsap\RASL11A, Hsap\DIRAS3, Hsap\RALA, Hsap\RHEBL1, Hsap\GEM, Hsap\RRAD, Hsap\RALB, Hsap\DIRAS2, Hsap\HRAS, Hsap\RRAS, Hsap\KRAS, Hsap\REM1, Hsap\RAP2B, Hsap\REM2, Hsap\ERAS, Hsap\DIRAS1, Hsap\MRAS, Hsap\RAP2A, Hsap\RIT1, Hsap\RAP2C, Hsap\RRAS2, Hsap\RASL12, Hsap\RAP1B, Hsap\RERGL, Hsap\RASD2, Hsap\RASL10B, Hsap\RHEB, Hsap\RERG, Hsap\RSG1, Hsap\RASD1, Hsap\NRAS, Hsap\RAP1A" "viable,fertile" FBgn0032305 CG6700 - http://flybase.org/reports/FBgn0032305 protein_coding_gene - - - CG6700 "IPR005062:SAC3/GANP/THP3, IPR015943:WD40/YVTN repeat-like-containing domain" CG6700 11-Aug-17 DroID_v2017_08 Drer\leng8 Scer\THP3 Cele\hpo-10 "Xtro\leng8, Xtro\LOC100495696" Mmus\Leng8 Hsap\LENG8 lethal FBgn0015520 nonA-l nonA-like http://flybase.org/reports/FBgn0015520 FBgn0026581 protein_coding_gene transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from biological aspect of ancestor with PANTHER:PTN000573360 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity poly-pyrimidine tract binding ; GO:0008187 | inferred from sequence or structural similarity with NCBI_gi:4826998 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000573351 regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000573360 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with NCBI_gi:4826998" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000573351 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with NCBI_gi:4826998 "nonA-l, Z, nonA-1, CG10328, nonA 1, LD09360, BEST:LD09360, PSF" "IPR000504:RNA recognition motif domain, IPR012975:NOPS" CG10328 11-Aug-17 DroID_v2017_08 "Drer\sfpq, Drer\nono, Drer\pspc1" Scer\NRD1 "Cele\psf-1, Cele\nono-1" "Xtro\nono, Xtro\sfpq" "Mmus\Sfpq, Mmus\Pspc1, Mmus\Nono" "Hsap\SFPQ, Hsap\PSPC1, Hsap\NONO" "viable,fertile,partially lethal - majority die,visible,lethal,wild-type" "eye,wing vein" FBgn0063670 CG40228 - http://flybase.org/reports/FBgn0063670 protein_coding_gene RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 transcription elongation factor complex ; GO:0008023 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 "BcDNA:RE67573, CG40228" IPR007808:Transcription elongation factor 1 CG40228 11-Aug-17 DroID_v2017_08 Drer\elof1 Scer\ELF1 Cele\Y54G11A.11 Xtro\elof1 "Mmus\Elof1, Mmus\Gm36718" Hsap\ELOF1 FBgn0025866 CalpB Calpain-B http://flybase.org/reports/FBgn0025866 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | inferred from direct assay calcium ion binding ; GO:0005509 | non-traceable author statement protein autoprocessing ; GO:0016540 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay protein autoprocessing ; GO:0016540 | traceable author statement border follicle cell migration ; GO:0007298 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype inferred from genetic interaction with Ca-β cytoplasm ; GO:0005737 | non-traceable author statement membrane ; GO:0016020 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CALPB, CG8107, CalpB, calpB" "IPR000169:Cysteine peptidase, cysteine active site, IPR001300:Peptidase C2, calpain, catalytic domain, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR033883:Calpain subdomain III, IPR022682:Peptidase C2, calpain, large subunit, domain III, IPR022683:Peptidase C2, calpain, domain III, IPR022684:Peptidase C2, calpain family" CG8107 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-50d11.2, Drer\capn2l, Drer\si:ch211-202f3.4, Drer\zgc:162184, Drer\capn3b, Drer\capn9, Drer\capn5b, Drer\zgc:136872, Drer\capn12, Drer\capn2b, Drer\capn8, Drer\capn10, Drer\capn15, Drer\capn1b, Drer\si:dkey-19b23.13, Drer\adgb, Drer\capn2a, Drer\zgc:85932, Drer\capn5a, Drer\capn1a, Drer\zgc:55262, Drer\zgc:92480, Drer\capn3a, Drer\si:ch211-202f3.3" "Scer\RIM13, Scer\PEF1" "Cele\clp-7, Cele\clp-6, Cele\clp-1, Cele\clp-4, Cele\clp-3" "Xtro\capn3, Xtro\capn2.2, Xtro\LOC100494922, Xtro\capn10, Xtro\capn1, Xtro\LOC100497805, Xtro\capn8, Xtro\capn15, Xtro\capn7, Xtro\capn13, Xtro\capn6, Xtro\capn9" "Mmus\Capn6, Mmus\Capn7, Mmus\Capn11, Mmus\Capn5, Mmus\Capn12, Mmus\Capn1, Mmus\Capn9, Mmus\Capn2, Mmus\Capn8, Mmus\Capn3, Mmus\Capn10, Mmus\Capn15, Mmus\Adgb, Mmus\Capn13" "Hsap\CAPN8, Hsap\CAPN11, Hsap\CAPN3, Hsap\CAPN2, Hsap\ADGB, Hsap\CAPN7, Hsap\CAPN15, Hsap\CAPN6, Hsap\CAPN9, Hsap\CAPN10, Hsap\CAPN14, Hsap\CAPN13, Hsap\CAPN12, Hsap\CAPN1, Hsap\CAPN5" "viable,fertile" border follicle cell FBgn0010317 CycJ Cyclin J http://flybase.org/reports/FBgn0010317 - protein_coding_gene cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from direct assay "mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of gene silencing by RNA ; GO:0060966 | inferred from genetic interaction with aub inferred from genetic interaction with piwi germarium-derived egg chamber formation ; GO:0007293 | inferred from genetic interaction with aub inferred from genetic interaction with piwi mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR004367 "cyclinJ, cycJ, Cdi5, CDI5, cdi5, CG10308, CycJ" "IPR004367:Cyclin, C-terminal domain, IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like" CG10308 11-Aug-17 DroID_v2017_08 "Drer\ccna2, Drer\ccna1, Drer\ccno, Drer\ccnj, Drer\ccnjl, Drer\si:ch211-132b12.8" "Scer\CLB5, Scer\CLN3, Scer\CLB3, Scer\CLB4, Scer\CLB6, Scer\CLN1, Scer\CLB2, Scer\CLB1, Scer\CLN2" "Cele\T24A6.1, Cele\cyb-2.1, Cele\cyb-1, Cele\W05G11.2, Cele\F08F1.9, Cele\T12C9.7, Cele\cya-2, Cele\T07F10.5, Cele\ZK678.3, Cele\cya-1, Cele\cyb-2.2" Xtro\ccnj "Mmus\Ccnj, Mmus\Ccno, Mmus\Ccnjl, Mmus\Ccna2, Mmus\Ccna1" "Hsap\CCNA2, Hsap\CCNO, Hsap\CCNA1, Hsap\CCNJL, Hsap\CNTD2, Hsap\CCNJ" " embryonic stage | early , adult stage | female " " embryonic stage | syncytial blastoderm , adult stage | female , embryonic stage | 0-3 hr , embryonic stage | cycle 1-10 , egg stage | unfertilized egg " " nurse cell

, unfertilized egg

" viable FBgn0031854 TTLL3A Tubulin tyrosine ligase-like 3A http://flybase.org/reports/FBgn0031854 protein_coding_gene "protein-glycine ligase activity ; GO:0070735 | inferred from direct assay protein-glycine ligase activity, initiating ; GO:0070736 | inferred from direct assay protein-glycine ligase activity, elongating ; GO:0070737 | inferred from direct assay" protein polyglycylation ; GO:0018094 | inferred from direct assay microtubule cytoskeleton ; GO:0015630 | inferred from direct assay "TTLL3A, dmTTLL3A, CG11323" IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase CG11323 11-Aug-17 DroID_v2017_08 "Drer\ttll1, Drer\ttl, Drer\ttll9, Drer\ttll5, Drer\ttll3, Drer\ttll2, Drer\ttll10" Scer\PBY1 - "Xtro\ttll5, Xtro\ttll2, Xtro\ttll3, Xtro\ttll1, Xtro\LOC100158544, Xtro\ttl" "Mmus\Ttll8, Mmus\Ttll10, Mmus\Ttll1, Mmus\Ttll5, Mmus\Ttll2, Mmus\Ttll3, Mmus\Ttl, Mmus\Ttll9" "Hsap\BRPF1, Hsap\TTLL3, Hsap\ARPC4, Hsap\TTLL1, Hsap\TTLL9, Hsap\TTLL5, Hsap\TTLL10, Hsap\ARPC4-TTLL3, Hsap\TTL, Hsap\TTLL8, Hsap\TTLL2" viable FBgn0004592 Eig71Ee Ecdysone-induced gene 71Ee http://flybase.org/reports/FBgn0004592 - protein_coding_gene structural molecule activity ; GO:0005198 | traceable author statement structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity with Sgs4 puparial adhesion ; GO:0007594 | inferred from sequence or structural similarity with Sgs4 puparial adhesion ; GO:0007594 | traceable author statement hemolymph coagulation ; GO:0042381 | inferred from direct assay hemolymph coagulation ; GO:0042381 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred by curator from GO:0007594 extracellular region ; GO:0005576 | inferred from sequence model "eig71Ee, I71-7, gp150, CG7604, L71, VII, gene VII, gene-VII, L71-7, Eig71Ee" - CG7604 11-Aug-17 DroID_v2017_08 - - - - - Hsap\MUC7 FBgn0032692 CG15161 - http://flybase.org/reports/FBgn0032692 protein_coding_gene molecular_function ; GO:0003674 | no biological data available intraciliary transport ; GO:0042073 | inferred from biological aspect of ancestor with PANTHER:PTN000332669 cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN000332669 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000332669 intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:1923818 cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:1923818 intraciliary transport particle B ; GO:0030992 | inferred from biological aspect of ancestor with PANTHER:PTN000332669 "CG15161, IFT46" IPR022088:Intraflagellar transport complex B protein 46 CG15161 11-Aug-17 DroID_v2017_08 Drer\ift46 - Cele\dyf-6 Xtro\ift46 Mmus\Ift46 Hsap\IFT46 viable FBgn0033739 Dyb Dystrobrevin http://flybase.org/reports/FBgn0033739 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC:3057 - dystrobrevin complex ; GO:0016014 | inferred from sequence or structural similarity dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity with HGNC:3057 inferred from sequence or structural similarity with HGNC:3058 "CG8529, DmDYB, Dyb" "IPR000433:Zinc finger, ZZ-type, IPR015153:EF-hand domain, type 1, IPR015154:EF-hand domain, type 2, IPR017432:Distrobrevin, IPR011992:EF-hand domain pair" CG8529 11-Aug-17 DroID_v2017_08 "Drer\dtnba, Drer\dtnbb, Drer\dmd, Drer\dtna, Drer\drp2" - Cele\dyb-1 Xtro\dtnb "Mmus\Utrn, Mmus\Dtnb, Mmus\Drp2, Mmus\Dtna, Mmus\Tusc1" "Hsap\DTNA, Hsap\TUSC1, Hsap\DTNB, Hsap\DRP2" viable FBgn0039358 CG5028 - http://flybase.org/reports/FBgn0039358 protein_coding_gene isocitrate dehydrogenase (NAD+) activity ; GO:0004449 | inferred from sequence or structural similarity with UniProtKB:P51553 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P51553 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P51553 microtubule associated complex ; GO:0005875 | inferred from direct assay CG5028 "IPR004434:Isocitrate dehydrogenase NAD-dependent, IPR024084:Isopropylmalate dehydrogenase-like domain" CG5028 11-Aug-17 DroID_v2017_08 "Drer\idh3b, Drer\idh3a, Drer\idh3g, Drer\zgc:165532" Scer\IDH1 "Cele\idhb-1, Cele\idhg-1, Cele\idhg-2, Cele\idha-1" "Xtro\idh3g, Xtro\idh3b, Xtro\idh3a" "Mmus\Idh3a, Mmus\Idh3b, Mmus\Idh3g, Mmus\4933405O20Rik" "Hsap\IDH3B, Hsap\IDH3A, Hsap\IDH3G" FBgn0264606 Fife Fife http://flybase.org/reports/FBgn0264606 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of neurotransmitter secretion ; GO:0001956 | inferred from mutant phenotype positive regulation of synaptic vesicle clustering ; GO:2000809 | inferred from mutant phenotype presynaptic active zone ; GO:0048786 | inferred from direct assay "CG43375, Fife, CG12187, CG16976, CG14950, fife, CG43955, anon-EST:Posey171" "IPR000008:C2 domain, IPR001478:PDZ domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011011:Zinc finger, FYVE/PHD-type" CG43955 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001274, Drer\LOC568486, Drer\grip1, Drer\il16, Drer\rims4, Drer\pdzd7b, Drer\pclob, Drer\lnx1, Drer\pcloa, Drer\rims1b, Drer\si:dkey-92i15.4, Drer\inadl, Drer\dlg5a, Drer\ska2, Drer\grip2b, Drer\grid2ipa, Drer\slc9a3r1, Drer\pard3bb" - "Cele\tag-80, Cele\unc-10" "Xtro\grip1, Xtro\dlg5, Xtro\grip2, Xtro\lnx1, Xtro\grid2ip" "Mmus\Grid2ip, Mmus\Pdzd2, Mmus\Il16, Mmus\Grasp, Mmus\Grip2, Mmus\Rims4, Mmus\Rims3, Mmus\Rims1, Mmus\Patj, Mmus\Pclo, Mmus\Lnx1, Mmus\Dlg5, Mmus\Pdzd11, Mmus\Pdzph1, Mmus\Mpdz, Mmus\Ush1c, Mmus\Rims2, Mmus\Bsn, Mmus\Grip1" "Hsap\PATJ, Hsap\BSN, Hsap\DLG5, Hsap\GRASP, Hsap\GRID2IP, Hsap\RIMS3, Hsap\USH1C, Hsap\RIMS1, Hsap\GRIP1, Hsap\PCLO, Hsap\FRMPD2, Hsap\PARD3B, Hsap\IL16, Hsap\LNX1, Hsap\PDZD2, Hsap\MPDZ, Hsap\RIMS2" FBgn0028956 mthl3 methuselah-like 3 http://flybase.org/reports/FBgn0028956 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "Mth-3, CG6530, gene 1, GENE 1, 104/8, l(2)k10408, BEST:GM02553, anon-WO0170980.53, anon-WO0170980.52, mthl3, mthl-3" "IPR017981:GPCR, family 2-like, IPR010596:Methuselah, N-terminal domain, IPR000832:GPCR, family 2, secretin-like, IPR023311:Methuselah ectodomain, domain 2" CG6530 11-Aug-17 DroID_v2017_08 "Drer\adgrg4a, Drer\adgrl4, Drer\fbn2b, Drer\adgrg3, Drer\adgrl2a, Drer\adgrg1, Drer\adgrl1a, Drer\adgrd2, Drer\adgrg2a, Drer\adgre14, Drer\fbn2a, Drer\adgre5b.3, Drer\adgrf6, Drer\LOC100537181, Drer\LOC100535070, Drer\LOC100538279, Drer\adgrl3.1, Drer\adgrf11, Drer\adgrg11, Drer\LOC101884341, Drer\LOC101886975, Drer\adgre10, Drer\adgrg6, Drer\adgrf3a" - Cele\lat-2 "Xtro\adgrf3, Xtro\adgrg1, Xtro\adgre5, Xtro\adgrv1, Xtro\adgrd1, Xtro\gpr157, Xtro\adgrf1, Xtro\adgrl1" "Mmus\Adgrg7, Mmus\Adgrd1, Mmus\Adgrf1, Mmus\Adgre4, Mmus\Adgrf3, Mmus\Adgrg4, Mmus\Adgrl1, Mmus\Adgrl4, Mmus\Adgrg2, Mmus\Adgrf2, Mmus\Adgrg5, Mmus\Adgrl3, Mmus\Adgre1, Mmus\Adgrl2, Mmus\Adgrf5, Mmus\Adgrg6, Mmus\Adgrg1, Mmus\Adgrf4, Mmus\Adgre5, Mmus\Adgrg3" "Hsap\ADGRG6, Hsap\ADGRF5, Hsap\ADGRE2, Hsap\ADGRL2, Hsap\ADGRL1, Hsap\ADGRE1, Hsap\ADGRG7, Hsap\ADGRE5, Hsap\ADGRD2, Hsap\ADGRG2, Hsap\ADGRG1, Hsap\ADGRE3, Hsap\FBN3, Hsap\ADGRF1, Hsap\ADGRL4, Hsap\ADGRF2, Hsap\ADGRG5, Hsap\ADGRF3, Hsap\ADGRF4, Hsap\ADGRL3, Hsap\ADGRG4, Hsap\ADGRD1, Hsap\ADGRG3" "viable,fertile" DRSC06997 K 1.394041873 -0.533985869 -0.357090399 -0.23893153 2.185723118 0.515978973 FBgn0038013 CG10038 - http://flybase.org/reports/FBgn0038013 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10038 IPR029058:Alpha/Beta hydrolase fold CG10038 11-Aug-17 DroID_v2017_08 "Drer\zgc:154040, Drer\fam172a, Drer\si:ch73-41e3.7, Drer\hrasls" - Cele\Y75B8A.31 Xtro\fam172a "Mmus\Pla2g16, Mmus\Hrasls5, Mmus\Hrasls, Mmus\Fam172a" "Hsap\HRASLS5, Hsap\FAM172A, Hsap\HRASLS2, Hsap\PLA2G16, Hsap\HRASLS" "viable,fertile" FBgn0033423 CG1809 - http://flybase.org/reports/FBgn0033423 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG1809 "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG1809 11-Aug-17 DroID_v2017_08 "Drer\alp3, Drer\alpi.1, Drer\alpi.2, Drer\alpl" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1" "Mmus\Alpi, Mmus\Alpl, Mmus\Alppl2, Mmus\Akp3" "Hsap\ALPI, Hsap\ALPPL2, Hsap\ALPL, Hsap\ALPP" viable FBgn0053532 lectin-37Da lectin-37Da http://flybase.org/reports/FBgn0053532 protein_coding_gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity galactose binding ; GO:0005534 | inferred from direct assay calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model inferred from direct assay "AC007082b, AC 007082B, CG9978, CG33532, lectin-37Da, DL2" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG33532 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-111e15.1, Drer\zmp:0000000924, Drer\cd209, Drer\LOC101884526, Drer\si:ch73-122g19.1, Drer\hbl4, Drer\LOC101882781, Drer\selp, Drer\zmp:0000000937, Drer\si:ch211-193e13.5, Drer\si:dkey-26c10.5" - "Cele\clec-45, Cele\clec-149, Cele\clec-28, Cele\clec-26, Cele\clec-39, Cele\clec-7, Cele\clec-31, Cele\clec-50, Cele\clec-198, Cele\clec-9, Cele\clec-17, Cele\F52E1.2, Cele\clec-4, Cele\clec-38" - "Mmus\Gm156, Mmus\Sell, Mmus\Cd207, Mmus\Clec12b, Mmus\Cd209b, Mmus\Clec9a, Mmus\Clec4e, Mmus\Cd209a, Mmus\Clec4g, Mmus\Cd209c, Mmus\Cd209e" "Hsap\CLEC4E, Hsap\CD207, Hsap\CLEC6A, Hsap\SFTPD, Hsap\CLEC4D" FBgn0038588 CG7156 - http://flybase.org/reports/FBgn0038588 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with JIL-1 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001036502 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with JIL-1 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001036502 CG7156 "IPR000719:Protein kinase domain, IPR001683:Phox homologous domain, IPR007330:MIT, IPR011009:Protein kinase-like domain" CG7156 11-Aug-17 DroID_v2017_08 "Drer\rps6kc1, Drer\kif16ba, Drer\snx25, Drer\rps6kl1, Drer\snx15" - Cele\rskd-1 "Xtro\rps6kc1, Xtro\snx15, Xtro\rps6kl1, Xtro\kif16b" "Mmus\Kif16b, Mmus\Sgk3, Mmus\Snx25, Mmus\Snx29, Mmus\Snx20, Mmus\Rps6kc1, Mmus\Snx15, Mmus\Rps6kl1, Mmus\Rps6ka5" "Hsap\SGK3, Hsap\RPS6KC1, Hsap\RPS6KL1, Hsap\SNX15, Hsap\SNX25" viable FBgn0262601 SmB Small ribonucleoprotein particle protein SmB http://flybase.org/reports/FBgn0262601 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:11153 "spermatogenesis ; GO:0007283 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000075760 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 gonad development ; GO:0008406 | inferred from mutant phenotype" pole plasm ; GO:0045495 | inferred from direct assay U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000075760 Cajal body ; GO:0015030 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000000831 U4 snRNP ; GO:0005687 | inferred from biological aspect of ancestor with PANTHER:PTN000075760 U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000075760 nucleus ; GO:0005634 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000075760 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000000831 precatalytic spliceosome ; GO:0071011 | inferred from direct assay U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000075760 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000075760 "SmB, CG5352, B, Sm B, snRNP B, SYM10, l(2)SH0509, l(2)SH2 0509, SmB1, dSmB, smb" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain" CG5352 11-Aug-17 DroID_v2017_08 "Drer\taf11, Drer\snrpb" Scer\SMB1 "Cele\snr-2, Cele\taf-11.2, Cele\taf-11.3" Xtro\snrpb "Mmus\Snurf, Mmus\Snrpn, Mmus\Snrpb, Mmus\Taf11" "Hsap\SNRPN, Hsap\TAF11, Hsap\SNRPB, Hsap\SNURF" DRSC03437 IEK -1.681650757 1.349981291 -0.785851337 -2.035756428 -0.158033788 2.025258392 FBgn0002873 mud mushroom body defect http://flybase.org/reports/FBgn0002873 "FBgn0052599, FBgn0030557" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with pins DNA binding ; GO:0003677 | inferred from direct assay "axon guidance ; GO:0007411 | inferred from genetic interaction with fra inferred from genetic interaction with NetA, NetB asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype mushroom body development ; GO:0016319 | traceable author statement mushroom body development ; GO:0016319 | inferred from mutant phenotype microtubule anchoring at centrosome ; GO:0034454 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype inferred from genetic interaction with dsh spindle assembly involved in female meiosis II ; GO:0007058 | inferred from mutant phenotype thermosensory behavior ; GO:0040040 | inferred from mutant phenotype" basal cortex ; GO:0045180 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay tricellular tight junction ; GO:0061689 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay "mud, Mud, CG12047, KS63, NuMA" - CG12047 11-Aug-17 DroID_v2017_08 "Drer\golga4, Drer\golgb1, Drer\cenpe, Drer\lamc1, Drer\golga3, Drer\numa1, Drer\LOC100332507, Drer\znf185, Drer\si:dkey-230p4.1" "Scer\MLP1, Scer\MLP2, Scer\USO1" "Cele\F59A2.2, Cele\anc-1, Cele\che-10, Cele\golg-4" Xtro\filip1 "Mmus\Golgb1, Mmus\Golga3, Mmus\Cenpe, Mmus\Cenpf, Mmus\Cep164, Mmus\Golga4, Mmus\Gcc2, Mmus\Krt17, Mmus\Numa1" "Hsap\FILIP1, Hsap\GOLGA3, Hsap\FILIP1L, Hsap\CENPE, Hsap\GOLGA4, Hsap\TAX1BP1, Hsap\HMMR, Hsap\GCC2, Hsap\CEP164, Hsap\CENPF, Hsap\NUMA1, Hsap\GOLGB1" " embryonic stage , larval stage , adult stage , larval stage | male " "partially lethal - majority die,female sterile,lethal,female,male fertile,wild-type,chemical sensitive,codominant,female limited,locomotor behavior defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage,sterile" "embryonic neuroblast,macrochaeta,Kenyon cell,adult mushroom body,vertical branch of mushroom body,adult central complex,egg,maternal effect,egg & chromatin | maternal effect,egg & spindle | maternal effect,calyx of adult mushroom body,medial lobe of adult mushroom body,lobe system of adult mushroom body,neuroblast,supernumerary,spindle,somatic clone,ganglion mother cell,neuropil,antennal lobe,centrosome,embryonic/larval neuroblast,astral microtubule,abdominal 2 ventro-medial neuroblast,abdominal 3 ventro-medial neuroblast,abdominal 4 ventro-medial neuroblast,abdominal 5 ventro-medial neuroblast,abdominal 6 ventro-medial neuroblast,abdominal 7 ventro-medial neuroblast,abdominal 2 dorso-lateral neuroblast,abdominal 3 dorso-lateral neuroblast,abdominal 4 dorso-lateral neuroblast,abdominal 5 dorso-lateral neuroblast,abdominal 6 dorso-lateral neuroblast,abdominal 7 dorso-lateral neuroblast,mushroom body pedunculus" FBgn0034527 CG9945 - http://flybase.org/reports/FBgn0034527 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay CG9945 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017399:WD repeat protein DCAF11/LEC14B" CG9945 11-Aug-17 DroID_v2017_08 "Drer\wdr5, Drer\ambra1a, Drer\wdr90, Drer\cfap52, Drer\dcaf11, Drer\wsb2" "Scer\CRN1, Scer\SWD3, Scer\TUP1" Cele\wdr-23 "Xtro\ambra1, Xtro\dcaf11, Xtro\wdr90, Xtro\wdr5" "Mmus\Dcaf11, Mmus\Wdr90, Mmus\Wsb2, Mmus\Wsb1, Mmus\Wdr38, Mmus\Wdr5, Mmus\Wdr95, Mmus\Nwd1, Mmus\Cfap52, Mmus\Ambra1" "Hsap\WDR38, Hsap\WDR90, Hsap\WDR88, Hsap\DCAF11, Hsap\WDR5, Hsap\CFAP52, Hsap\WSB2, Hsap\WDR5B" viable FBgn0259994 CG42492 - http://flybase.org/reports/FBgn0259994 protein_coding_gene - - - "CG42492, anon-WO0140519.181, CG11473, CG17761" IPR004878:Otopetrin CG42492 11-Aug-17 DroID_v2017_08 "Drer\otop2, Drer\otop1" - "Cele\otpl-3, Cele\otpl-2, Cele\otpl-5, Cele\otpl-7, Cele\otpl-4, Cele\otpl-8, Cele\otpl-1, Cele\otpl-6" "Xtro\otop2, Xtro\otop1, Xtro\otop3" "Mmus\Otop2, Mmus\Otop3, Mmus\Otop1" "Hsap\OTOP2, Hsap\OTOP3, Hsap\OTOP1" FBgn0034494 CG10444 - http://flybase.org/reports/FBgn0034494 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "CG10444, dSLC5A3" IPR001734:Sodium/solute symporter CG10444 11-Aug-17 DroID_v2017_08 "Drer\slc5a9, Drer\slc5a6a, Drer\slc5a8l, Drer\slc5a5, Drer\slc5a12, Drer\slc5a8, Drer\slc5a6b" Scer\DUR3 "Cele\F52H2.4, Cele\ZK822.5" "Xtro\slc5a8, Xtro\slc5a2, Xtro\slc5a12, Xtro\slc5a5" "Mmus\Slc5a6, Mmus\Slc5a5, Mmus\Slc5a12, Mmus\Slc5a8, Mmus\Slc5a9" "Hsap\SLC5A12, Hsap\SLC5A9, Hsap\SLC5A6, Hsap\SLC5A8, Hsap\SLC5A5" "lethal,viable,fertile" FBgn0031470 CG18557 - http://flybase.org/reports/FBgn0031470 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "c-SPH125, CG18557" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG18557 11-Aug-17 DroID_v2017_08 Drer\f7 - Cele\try-1 - "Mmus\Klk1b24, Mmus\Klk1b5, Mmus\Klk1b3, Mmus\F11, Mmus\Klk1b11, Mmus\Klk1b1, Mmus\Klk11, Mmus\Klk1b8, Mmus\F9, Mmus\Klk1b26, Mmus\Klk1b4, Mmus\Klkb1, Mmus\Egfbp2, Mmus\Klk1, Mmus\Klk1b9, Mmus\Klk1b16, Mmus\Klk1b22, Mmus\Klk1b21, Mmus\Klk1b27" "Hsap\KLK1, Hsap\PLG, Hsap\KLK11, Hsap\KLK2, Hsap\KLKB1, Hsap\KLK3, Hsap\F11, Hsap\F9, Hsap\F10" viable FBgn0013773 Cyp6a22 Cyp6a22 http://flybase.org/reports/FBgn0013773 FBgn0033976 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "Cyp6a22, 6a22, P450, BF6-2, P-450, Cyt-P450-rBF6-2, CG10240, cyp6a22" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10240 11-Aug-17 DroID_v2017_08 "Drer\cyp4v8, Drer\cyp4f3, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp4v7, Drer\tbxas1, Drer\cyp3c4, Drer\cyp3a65, Drer\cyp3c2, Drer\cyp4t8" Scer\ERG11 "Cele\cyp-25A4, Cele\cyp-13A11, Cele\cyp-13A4, Cele\cyp-13A5, Cele\cyp-13A1, Cele\cyp-25A2, Cele\cyp-13A6, Cele\cyp-43A1, Cele\cyp-25A6, Cele\cyp-13A8, Cele\cyp-13A2, Cele\cyp-13B2, Cele\cyp-29A2, Cele\cyp-13A12, Cele\cyp-13A3, Cele\cyp-29A4, Cele\cyp-13A10, Cele\cyp-42A1, Cele\cyp-33C1, Cele\cyp-25A3, Cele\cyp-32B1, Cele\cyp-44A1, Cele\cyp-13A7, Cele\cyp-31A3, Cele\cyp-29A3, Cele\cyp-32A1, Cele\cyp-25A1, Cele\cyp-13B1, Cele\cyp-37B1, Cele\cyp-31A2" "Xtro\cyp3a4, Xtro\LOC100494419, Xtro\cyp3a5, Xtro\tbxas1" "Mmus\Cyp4f16, Mmus\Cyp4v3, Mmus\Cyp1a1, Mmus\Cyp3a13, Mmus\Cyp3a57, Mmus\Cyp3a41a, Mmus\Cyp4a12a, Mmus\Cyp4f39, Mmus\Cyp4a10, Mmus\Cyp4f15, Mmus\Cyp3a16, Mmus\Cyp4f18, Mmus\Cyp4f14, Mmus\Cyp4a14, Mmus\Cyp3a41b, Mmus\Cyp4f37, Mmus\Cyp4b1, Mmus\Cyp4a12b, Mmus\Cyp4f13, Mmus\Cyp3a25, Mmus\Tbxas1, Mmus\Cyp4a31, Mmus\Cyp3a44, Mmus\Cyp3a59, Mmus\Cyp3a11, Mmus\Cyp4a32" "Hsap\CYP4F22, Hsap\CYP4X1, Hsap\CYP3A7, Hsap\TBXAS1, Hsap\CYP4V2, Hsap\CYP4F8, Hsap\CYP1A1, Hsap\CYP4B1, Hsap\CYP4F2, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4Z1, Hsap\CYP3A43, Hsap\CYP4F11, Hsap\CYP4F12, Hsap\CYP4A22, Hsap\CYP3A5, Hsap\CYP4F3, Hsap\CYP4A11, Hsap\CYP3A4" viable FBgn0259108 futsch futsch http://flybase.org/reports/FBgn0259108 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with UniProtKB:P46821 inferred from direct assay microtubule binding ; GO:0008017 | inferred from direct assay kinase binding ; GO:0019900 | inferred from physical interaction with UniProtKB:Q5S007 inferred from physical interaction with UniProtKB:Q9VDJ9 protein binding ; GO:0005515 | inferred from physical interaction with Fmr1 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity olfactory learning ; GO:0008355 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | non-traceable author statement nervous system development ; GO:0007399 | non-traceable author statement neurofilament cytoskeleton organization ; GO:0060052 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype compound eye development ; GO:0048749 | non-traceable author statement axonogenesis ; GO:0007409 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR026074 microtubule associated complex ; GO:0005875 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay microtubule cytoskeleton ; GO:0015630 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity dendrite ; GO:0030425 | inferred from direct assay "22C10, futsch, Map1B, CG34387, Futsch, 22c10, mAb22C10, mAb 22C10, MAb22C10, ssC10, 22C10/FUTSCH, MAP1B, map1b, EG:49E4.1, Mab22C10, mAb-22C10, CG3064, Mab 22C10, CG14772, MAP-IB, olk, Olk, mAb22c10, FUTSCH, 22C20, Mab22c10, Futch, lincRNA.936, Map-1B" "IPR009603:Microtubule associated protein Futsch, IPR001279:Metallo-beta-lactamase, IPR026074:Microtubule associated protein 1" CG34387 11-Aug-17 DroID_v2017_08 "Drer\rp1l1a, Drer\tp53bp1, Drer\phf3, Drer\rai1, Drer\map1sa, Drer\map1aa, Drer\map1sb, Drer\map1b, Drer\map1ab" - "Cele\unc-44, Cele\maph-1.1, Cele\maph-1.2" "Xtro\map1b, Xtro\rai1" "Mmus\Rai1, Mmus\Map2, Mmus\Trp53bp1, Mmus\Map1s, Mmus\Mia3, Mmus\Mdc1, Mmus\Phf3, Mmus\Bdp1, Mmus\Map1a, Mmus\Map1b" "Hsap\TCF20, Hsap\MAP1A, Hsap\NES, Hsap\BDP1, Hsap\MAP1S, Hsap\BOD1L1, Hsap\RAI1, Hsap\MAP1B, Hsap\MIA3, Hsap\PHF3, Hsap\MKI67, Hsap\TP53BP1, Hsap\MUC12, Hsap\MAP2, Hsap\MDC1" FBgn0035356 CG16986 - http://flybase.org/reports/FBgn0035356 protein_coding_gene acyl-CoA hydrolase activity ; GO:0047617 | inferred from sequence or structural similarity with HGNC:20999 acyl-CoA hydrolase activity ; GO:0047617 | inferred from biological aspect of ancestor with PANTHER:PTN000494087 protein homotetramerization ; GO:0051289 | inferred from sequence or structural similarity with HGNC:20999 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000494087 CG16986 "IPR003736:Phenylacetic acid degradation-related domain, IPR006683:Thioesterase domain, IPR029069:HotDog domain" CG16986 11-Aug-17 DroID_v2017_08 "Drer\acot13, Drer\them4" - "Cele\C25H3.14, Cele\C25H3.3, Cele\F42H10.6" Xtro\acot13 Mmus\Acot13 Hsap\ACOT13 "viable,fertile" DRSC08502 E -0.188418959 0.875263803 1.521510357 0.896382162 0.525447332 -1.079536714 FBgn0050000 GstT1 Glutathione S transferase T1 http://flybase.org/reports/FBgn0050000 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG12930B, CG12930, BcDNA:RE63575, CG30000, GstT1, gstt1, GSTT1, DmGSTT1" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG30000 11-Aug-17 DroID_v2017_08 "Drer\gstt2, Drer\vars, Drer\eef1g, Drer\gstt1a, Drer\gstt1b, Drer\gstr, Drer\mars, Drer\eef1e1" "Scer\GTT2, Scer\GTT1, Scer\CAM1, Scer\TEF4, Scer\URE2, Scer\YGR201C" "Cele\gst-21, Cele\gst-29, Cele\gst-35" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Gstt1, Mmus\Eef1e1, Mmus\Mars, Mmus\Gstt4, Mmus\Gstt3, Mmus\Eef1g, Mmus\Gstt2, Mmus\Vars" "Hsap\EEF1E1, Hsap\GSTT2B, Hsap\VARS, Hsap\GSTT1, Hsap\EEF1G, Hsap\GSTT2, Hsap\MARS" viable FBgn0021761 Nup154 Nucleoporin 154kD http://flybase.org/reports/FBgn0021761 "FBgn0010493, FBgn0016083, FBgn0027862" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Nup93-1 chromatin binding ; GO:0003682 | inferred from direct assay structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000039103 RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000039103 regulation of protein localization to membrane ; GO:1905475 | inferred from mutant phenotype protein targeting to nuclear inner membrane ; GO:0036228 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery ; GO:0000972 | inferred from biological aspect of ancestor with PANTHER:PTN000039103 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000039103 nuclear envelope ; GO:0005635 | colocalizes_with inferred from direct assay nuclear pore ; GO:0005643 | non-traceable author statement nuclear envelope ; GO:0005635 | inferred from direct assay nuclear pore inner ring ; GO:0044611 | inferred from biological aspect of ancestor with PANTHER:PTN000039103 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "nup154, l(2)01501, zk, nup32D, Nup32D, l(2)10432, tlp, ms(2)zk, CG4579, BcDNA:LD21772, Nup154, tip, Nup155, Nup" "IPR004870:Nucleoporin, Nup155-like, IPR015943:WD40/YVTN repeat-like-containing domain, IPR007187:Nucleoporin, Nup133/Nup155-like, C-terminal, IPR014908:Nucleoporin, Nup133/Nup155-like, N-terminal" CG4579 11-Aug-17 DroID_v2017_08 Drer\nup155 "Scer\NUP170, Scer\NUP157" Cele\npp-8 Xtro\nup155 Mmus\Nup155 Hsap\NUP155 " embryonic stage | stage >=11 , embryonic stage | stage 8-9 , embryonic stage | stage 16-17 , embryonic stage&&larval stage&&adult stage , embryonic stage | 0-2hr , embryonic stage | stage 14 , embryonic stage | stage 16,17 , larval stage , adult stage && oogenesis stage , embryonic stage | stage 5-9 , adult stage | male " " embryonic/larval midgut

, mesoderm

, germline cell

, embryonic/larval hindgut

,

ubiquitous , embryonic/larval dorsal vessel

, lymph gland

, imaginal disc

, egg chamber

, embryonic brain | restricted

, germarium

, embryonic/larval foregut

, pole cell | vicinity of

, embryonic central nervous system

, embryonic brain

, testis

, larval brain | restricted

" adult stage && oogenesis stage " germarium

, spermatocyte

, oocyte

, egg chamber

" "male fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,male sterile,female sterile,recessive,viable,lethal,female semi-sterile,female fertile,wild-type,partially lethal - majority die,visible,cell growth defective" "testis,ovary,germline cell,male,egg chamber,embryonic/larval brain,embryonic/larval optic lobe,imaginal disc,embryonic/larval lymph gland,spermatid,meiotic cell cycle | male,ovariole,egg,dorsal appendage,follicle cell,oocyte,nurse cell,testis & meiotic cell cycle,cyst cell,cyst cell & spindle,spermatid axoneme,spermatocyte,spermatocyte & nuclear membrane,nurse cell & chromatin,embryonic/larval hemocyte,mesothoracic tergum" FBgn0026315 Ugt35a UDP-glycosyltransferase 35a http://flybase.org/reports/FBgn0026315 "FBgn0015835, FBgn0040254" protein_coding_gene UDP-glycosyltransferase activity ; GO:0008194 | inferred from sequence or structural similarity with UniProtKB:P18569 glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with UniProtKB:P18569 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 integral component of membrane ; GO:0016021 | inferred from sequence model "AC 006491F, DmeUgt35a, Ugt86Df, UDPGT1, CG6644, Ugt35a, ugt35a" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG6644 11-Aug-17 DroID_v2017_08 "Drer\ugt2b1, Drer\ugt2a3, Drer\ugt2b6, Drer\ugt1b5, Drer\ugt5a2, Drer\ugt5a1, Drer\ugt2a1, Drer\ugt1b4, Drer\ugt5c3, Drer\ugt5g1, Drer\ugt5g2, Drer\zgc:172315, Drer\ugt5b1, Drer\ugt5b4, Drer\ugt2b5, Drer\ugt5e1, Drer\ugt2b3, Drer\ugt5f1, Drer\ugt2a5, Drer\ugt5d1, Drer\ugt2a2, Drer\ugt5b2, Drer\ugt1b2, Drer\ugt2a6, Drer\ugt2a4, Drer\ugt5b6, Drer\ugt1b7, Drer\ugt1ab, Drer\ugt5a4, Drer\ugt5b3, Drer\ugt8, Drer\ugt5c2, Drer\ugt5c1, Drer\ugt1b3, Drer\ugt5a5" Scer\ATG26 "Cele\ugt-16, Cele\ugt-5, Cele\ugt-51, Cele\F10D2.8, Cele\ugt-53, Cele\H23N18.4, Cele\ugt-60, Cele\ugt-49, Cele\ugt-18, Cele\ugt-55, Cele\C23G10.6, Cele\ugt-36, Cele\ugt-47, Cele\ugt-22, Cele\K04A8.10, Cele\C55H1.1, Cele\ugt-10, Cele\ugt-25, Cele\ugt-39, Cele\ugt-65, Cele\ugt-56, Cele\ugt-11, Cele\ugt-52, Cele\ugt-59, Cele\ugt-32, Cele\ugt-31, Cele\ugt-45, Cele\ugt-15, Cele\ugt-62, Cele\ugt-14, Cele\ugt-7, Cele\ugt-3, Cele\ugt-33, Cele\ugt-24, Cele\ugt-28, Cele\ugt-12, Cele\ugt-21, Cele\ugt-44, Cele\ugt-41, Cele\ugt-8, Cele\ugt-46, Cele\ugt-54, Cele\ugt-34, Cele\ugt-9, Cele\ugt-6, Cele\ugt-61, Cele\ugt-57, Cele\ugt-4, Cele\ugt-26, Cele\C03A7.12, Cele\ugt-30, Cele\ugt-40, Cele\ugt-17, Cele\ugt-20, Cele\ugt-2, Cele\ugt-35, Cele\ugt-37, Cele\ugt-13, Cele\C03A7.13, Cele\ugt-38, Cele\ugt-43, Cele\F54C1.1, Cele\ugt-27, Cele\ugt-63, Cele\ugt-48, Cele\ugt-50, Cele\ugt-1, Cele\ugt-42, Cele\ugt-29, Cele\Y43D4A.2, Cele\ugt-23, Cele\ugt-58, Cele\ugt-19" "Xtro\ugt1a6, Xtro\ugt2a1, Xtro\ugt2b4, Xtro\ugt8, Xtro\ugt3a2" "Mmus\Ugt1a10, Mmus\Ugt2a1, Mmus\Ugt2b5, Mmus\Ugt3a1, Mmus\Ugt1a1, Mmus\Ugt1a9, Mmus\Ugt1a7c, Mmus\Ugt2b37, Mmus\Ugt2b36, Mmus\Ugt2a3, Mmus\Ugt8a, Mmus\Ugt2a2, Mmus\Ugt2b1, Mmus\Ugt1a5, Mmus\Ugt2b35, Mmus\Ugt3a2, Mmus\Ugt1a6b, Mmus\Ugt2b38, Mmus\Ugt2b34, Mmus\Ugt1a2" "Hsap\UGT1A8, Hsap\UGT2A3, Hsap\UGT1A7, Hsap\UGT2B28, Hsap\UGT2A2, Hsap\UGT1A4, Hsap\UGT3A2, Hsap\UGT1A3, Hsap\UGT2B17, Hsap\UGT8, Hsap\UGT2B15, Hsap\UGT1A9, Hsap\UGT1A1, Hsap\UGT2B4, Hsap\UGT2B7, Hsap\UGT2B11, Hsap\UGT1A10, Hsap\UGT1A6, Hsap\UGT3A1, Hsap\UGT2B10, Hsap\UGT1A5" adult stage " leg

, antennal segment 3

" FBgn0052750 CG32750 - http://flybase.org/reports/FBgn0052750 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ; GO:0016811 | inferred from electronic annotation with InterPro:IPR012101 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from biological aspect of ancestor with PANTHER:PTN000064607" nitrogen compound metabolic process ; GO:0006807 | inferred from electronic annotation with InterPro:IPR003010 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3648, CG32750" "IPR003010:Carbon-nitrogen hydrolase, IPR012101:Biotinidase, eukaryotic" CG32750 11-Aug-17 DroID_v2017_08 "Drer\nit2, Drer\btd" "Scer\NIT3, Scer\NTA1" - "Xtro\vnn1, Xtro\nit2, Xtro\btd" "Mmus\Vnn3, Mmus\Vnn1, Mmus\Nit2, Mmus\Btd" "Hsap\VNN1, Hsap\VNN2, Hsap\VNN3, Hsap\BTD, Hsap\NIT2" FBgn0030449 Fer3HCH Ferritin 3 heavy chain homologue http://flybase.org/reports/FBgn0030449 protein_coding_gene "ferric iron binding ; GO:0008199 | inferred from electronic annotation with InterPro:IPR001519, InterPro:IPR008331 iron ion binding ; GO:0005506 | inferred from biological aspect of ancestor with PANTHER:PTN000153092" iron ion transport ; GO:0006826 | inferred from electronic annotation with InterPro:IPR001519 positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype cellular response to iron ion starvation ; GO:0010106 | inferred from mutant phenotype intracellular sequestering of iron ion ; GO:0006880 | inferred from biological aspect of ancestor with PANTHER:PTN000153092 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000153092 "Fer3HCH, CG4349, Fer3 HCH, Fer3" "IPR008331:Ferritin/DPS protein domain, IPR009040:Ferritin-like diiron domain, IPR009078:Ferritin-like superfamily, IPR012347:Ferritin-related, IPR001519:Ferritin, IPR014034:Ferritin, conserved site" CG4349 11-Aug-17 DroID_v2017_08 "Drer\zgc:198419, Drer\zgc:92066, Drer\zgc:172145, Drer\zgc:109934, Drer\zgc:173594, Drer\fth1a, Drer\zgc:173593, Drer\fth1b, Drer\zgc:194125, Drer\zgc:56095, Drer\LOC100006428, Drer\LOC558816" - "Cele\ftn-2, Cele\ftn-1" "Xtro\fth1, Xtro\ftmt, Xtro\MGC79725, Xtro\MGC75752, Xtro\MGC76132" "Mmus\Fthl17c, Mmus\Fth1, Mmus\Gm813, Mmus\Ftmt, Mmus\E330017A01Rik, Mmus\Fthl17d, Mmus\Fthl17e, Mmus\Ftl1, Mmus\Fthl17f, Mmus\Fthl17a, Mmus\Fthl17b" "Hsap\FTL, Hsap\FTMT, Hsap\FTHL17, Hsap\FTH1" viable DRSC19892 K -0.811924654 0.202152782 -0.017299349 0.189199491 1.516577578 0.123062004 FBgn0036376 Liprin-beta Liprin-beta http://flybase.org/reports/FBgn0036376 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Liprin-α protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Liprin-β synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype axon target recognition ; GO:0007412 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from direct assay "Liprin-beta, CG10743" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain, IPR030444:Liprin-beta, IPR029515:LAR-interacting protein, Liprin" CG10743 11-Aug-17 DroID_v2017_08 "Drer\ppfibp1a, Drer\ppfibp1b, Drer\ppfibp2b, Drer\ppfibp2a" - Cele\hlb-1 "Xtro\ppfibp2, Xtro\ppfibp1" "Mmus\Ppfibp2, Mmus\Ppfibp1" "Hsap\PPFIBP1, Hsap\PPFIBP2" "neuroanatomy defective,partially lethal - majority die,recessive,viable" "photoreceptor cell R7,medulla,NMJ bouton" FBgn0034261 HPS4 Hermansky-Pudlak Syndrome 4 http://flybase.org/reports/FBgn0034261 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype miRNA loading onto RISC involved in gene silencing by miRNA ; GO:0035280 | inferred from mutant phenotype siRNA loading onto RISC involved in chromatin silencing by small RNA ; GO:0070923 | inferred from mutant phenotype late endosome membrane ; GO:0031902 | inferred from direct assay BLOC-3 complex ; GO:0031085 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from direct assay BLOC-3 complex ; GO:0031085 | inferred from sequence or structural similarity with HGNC:15844 "dHPS4, HPS4, CG4966, NP_725707" IPR026091:Hermansky-Pudlak syndrome 4 protein CG4966 11-Aug-17 DroID_v2017_08 Drer\hps4 - - - Mmus\Hps4 Hsap\HPS4 "viable,fertile" DRSC06906 E 0.440450544 -0.065199931 -2.081890088 0.704641029 0.513030281 -0.007097266 FBgn0259168 mnb minibrain http://flybase.org/reports/FBgn0259168 protein_coding_gene "protein serine/threonine/tyrosine kinase activity ; GO:0004712 | inferred from electronic annotation with InterPro:IPR028318 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement" protein autophosphorylation ; GO:0046777 | inferred from electronic annotation with InterPro:IPR028318 positive regulation of hippo signaling ; GO:0035332 | inferred from mutant phenotype positive regulation of neuron differentiation ; GO:0045666 | inferred from expression pattern positive regulation of feeding behavior ; GO:2000253 | inferred from mutant phenotype negative regulation of cell cycle ; GO:0045786 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement olfactory learning ; GO:0008355 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from genetic interaction with so learning or memory ; GO:0007611 | non-traceable author statement nervous system development ; GO:0007399 | inferred from mutant phenotype positive regulation of growth ; GO:0045927 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from mutant phenotype positive regulation of synaptic vesicle endocytosis ; GO:1900244 | inferred from mutant phenotype terminal bouton ; GO:0043195 | inferred from direct assay "minibrain, mnb, CG42273, Mnb, Dyrk1, CG7826, ME-IV, min, CG7835, MNB, DYRK1, Dm1, DmDyrk1A, Dyrk1A" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR028318:Dual specificity tyrosine-phosphorylation-regulated kinase 1A" CG42273 11-Aug-17 DroID_v2017_08 "Drer\hipk3a, Drer\dyrk1ab, Drer\dyrk1b, Drer\si:ch211-160o17.4, Drer\hipk2, Drer\dyrk4, Drer\hipk3b, Drer\zgc:172180, Drer\hipk1a, Drer\dyrk2, Drer\dyrk1aa" Scer\YAK1 "Cele\C36B7.1, Cele\mbk-2, Cele\mbk-1, Cele\C36B7.2, Cele\hpk-1" "Xtro\dyrk2, Xtro\hipk3, Xtro\dyrk1a, Xtro\dyrk3, Xtro\hipk1, Xtro\hipk2" "Mmus\Hipk1, Mmus\Hipk2, Mmus\Dyrk3, Mmus\Dyrk1a, Mmus\Dyrk1b, Mmus\Hipk4, Mmus\Dyrk4, Mmus\Dyrk2, Mmus\Hipk3" "Hsap\DYRK4, Hsap\DYRK3, Hsap\DYRK2, Hsap\DYRK1A, Hsap\HIPK1, Hsap\HIPK2, Hsap\HIPK4, Hsap\HIPK3, Hsap\DYRK1B" embryonic stage " supraesophageal ganglion

, ventral nerve cord

" " embryonic stage -- adult stage , larval stage , adult stage , larval stage && pupal stage " " mushroom body

, larval outer optic anlage

, mushroom body gamma-lobe

, retina

, pigment cell

, mushroom body beta-lobe

, larval optic lobe

" FBgn0039201 CG13617 - http://flybase.org/reports/FBgn0039201 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN001469899 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001469871 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN000948208 "CG13617, Dzip1" "IPR032714:Zinc finger protein DZIP1, N-terminal, IPR013087:Zinc finger C2H2-type" CG13617 11-Aug-17 DroID_v2017_08 "Drer\dzip1, Drer\dzip1l" - - "Xtro\dzip1, Xtro\dzip1l" "Mmus\Dzip1, Mmus\Dzip1l" "Hsap\DZIP1, Hsap\DZIP1L" viable FBgn0053813 His1:CG33813 His1:CG33813 http://flybase.org/reports/FBgn0053813 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33813, His1:CG33813" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33813 11-Aug-17 DroID_v2017_08 "Drer\zgc:110425, Drer\si:dkey-108k21.14, Drer\histh1l, Drer\h1fx, Drer\h1m, Drer\si:dkey-261m9.12, Drer\zgc:110216, Drer\zgc:153405, Drer\si:ch1073-159d7.7, Drer\h1f0, Drer\si:ch211-113a14.24, Drer\si:dkey-108k21.21, Drer\zgc:163061, Drer\si:ch73-36p18.1, Drer\si:dkey-108k21.10" Scer\HHO1 "Cele\hil-5, Cele\hil-4, Cele\hil-6, Cele\hil-2, Cele\hil-3, Cele\hil-1, Cele\his-24" - "Mmus\Hist1h1a, Mmus\Hist1h1t, Mmus\Hist1h1b, Mmus\Hils1, Mmus\H1fx, Mmus\H1fnt, Mmus\Hist1h1c, Mmus\Hist1h1e, Mmus\Hist1h1d, Mmus\H1foo" "Hsap\HIST1H1E, Hsap\H1F0, Hsap\HIST1H1T, Hsap\HIST1H1A, Hsap\H1FNT, Hsap\H1FOO, Hsap\HIST1H1C, Hsap\HIST1H1D, Hsap\HIST1H1B, Hsap\H1FX" FBgn0019932 SamDC S-adenosylmethionine decarboxylase http://flybase.org/reports/FBgn0019932 "FBgn0014220, FBgn0014221, FBgn0014222, FBgn0024936" protein_coding_gene adenosylmethionine decarboxylase activity ; GO:0004014 | inferred from biological aspect of ancestor with PANTHER:PTN000170807 spermine biosynthetic process ; GO:0006597 | inferred from biological aspect of ancestor with PANTHER:PTN000170807 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype spermidine biosynthetic process ; GO:0008295 | inferred from biological aspect of ancestor with PANTHER:PTN000170807 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000170807 "CG5029, l(2)31De, l(2)31Dd, l(2)31Dc, SamDC" "IPR018166:S-adenosylmethionine decarboxylase, conserved site, IPR001985:S-adenosylmethionine decarboxylase, IPR016067:S-adenosylmethionine decarboxylase, core" CG5029 11-Aug-17 DroID_v2017_08 Drer\amd1 Scer\SPE2 Cele\smd-1 Xtro\amd1 "Mmus\Amd2, Mmus\Amd1" Hsap\AMD1 embryonic stage -- adult stage "lethal,recessive,visible,viable" macrochaeta DRSC03429 I 1.919139436 1.266253248 -0.496320004 1.333449635 -0.538493908 0.158053736 FBgn0035944 CG5021 - http://flybase.org/reports/FBgn0035944 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vesicle-mediated transport ; GO:0016192 | inferred from biological aspect of ancestor with PANTHER:PTN000314393 protein secretion ; GO:0009306 | inferred from biological aspect of ancestor with PANTHER:PTN000314393 integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000314393 CG5021 "IPR008564:Protein of unknown function DUF846, eukaryotic" CG5021 11-Aug-17 DroID_v2017_08 "Drer\tvp23b, Drer\zgc:112148" Scer\TVP23 Cele\C34D4.4 "Xtro\tvp23b, Xtro\tvp23a" "Mmus\Tvp23b, Mmus\Tvp23a" "Hsap\TVP23A, Hsap\TVP23C-CDRT4, Hsap\TVP23B, Hsap\TVP23C, Hsap\CDRT4" "viable,visible" "trichogen cell,supernumerary" FBgn0004430 LysS Lysozyme S http://flybase.org/reports/FBgn0004430 "FBgn0002575, FBgn0063108" protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 lysozyme activity ; GO:0003796 | inferred from sequence or structural similarity - - "LysS, lysS, CG1165, BcDNA:LP06719" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CG1165 11-Aug-17 DroID_v2017_08 "Drer\lyz, Drer\LOC100536671, Drer\LOC100334363" - - Xtro\MGC89221 "Mmus\1700016D06Rik, Mmus\Spaca3, Mmus\Spaca5, Mmus\Lyz2, Mmus\Lyzl6, Mmus\Lyz1, Mmus\Lyzl4, Mmus\Spaca4, Mmus\Lyzl1, Mmus\Spaca7, Mmus\Lalba, Mmus\Spaca1, Mmus\9530003J23Rik" "Hsap\LYZ, Hsap\LALBA, Hsap\SPACA5, Hsap\SPACA1, Hsap\LYZL2, Hsap\SPACA5B, Hsap\LYZL4, Hsap\LYZL6, Hsap\SPACA3, Hsap\LYZL1, Hsap\SPACA4, Hsap\SPACA7" larval stage gastric caecum

viable FBgn0053804 His1:CG33804 His1:CG33804 http://flybase.org/reports/FBgn0053804 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33804, His1:CG33804" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33804 11-Aug-17 DroID_v2017_08 "Drer\h1fx, Drer\si:ch211-113a14.24, Drer\si:dkey-261m9.12, Drer\si:dkey-108k21.14, Drer\zgc:153405, Drer\si:ch1073-159d7.7, Drer\zgc:163061, Drer\zgc:110425, Drer\h1m, Drer\si:dkey-108k21.21, Drer\zgc:110216, Drer\si:ch73-36p18.1, Drer\si:dkey-108k21.10, Drer\histh1l, Drer\h1f0" Scer\HHO1 "Cele\his-24, Cele\hil-5, Cele\hil-6, Cele\hil-4, Cele\hil-1, Cele\hil-2, Cele\hil-3" - "Mmus\Hist1h1c, Mmus\H1fx, Mmus\Hist1h1d, Mmus\H1foo, Mmus\Hist1h1t, Mmus\Hist1h1a, Mmus\H1fnt, Mmus\Hist1h1b, Mmus\Hils1, Mmus\Hist1h1e" "Hsap\H1F0, Hsap\HIST1H1E, Hsap\HIST1H1T, Hsap\HIST1H1D, Hsap\H1FX, Hsap\HIST1H1A, Hsap\H1FNT, Hsap\HIST1H1B, Hsap\H1FOO, Hsap\HIST1H1C" FBgn0032516 Ing5 Inhibitor of growth family member 5 http://flybase.org/reports/FBgn0032516 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 histone acetyltransferase activity (H3-K23 specific) ; GO:0043994 | inferred from direct assay regulation of cell cycle ; GO:0051726 | inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay MOZ/MORF histone acetyltransferase complex ; GO:0070776 | inferred from direct assay "CG9293, Ing5" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR024610:Inhibitor of growth protein, N-terminal histone-binding, IPR028651:ING family, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9293 11-Aug-17 DroID_v2017_08 "Drer\ing1, Drer\ing4, Drer\ing5a, Drer\taf3, Drer\ing5b, Drer\ing3, Drer\ing2" "Scer\YNG2, Scer\YNG1, Scer\PHO23" "Cele\lsy-13, Cele\Y43H11AL.1, Cele\ing-3" "Xtro\ing2, Xtro\ing5, Xtro\ing3, Xtro\taf3, Xtro\ing4, Xtro\ing1" "Mmus\Ing5, Mmus\Ing2, Mmus\Ing3, Mmus\Ing1, Mmus\Taf3, Mmus\Ing4" "Hsap\ING4, Hsap\TAF3, Hsap\ING1, Hsap\ING5, Hsap\ING2, Hsap\ING3" "viable,fertile" DRSC03188 I -1.015864702 -2.5650718 0.061734833 1.255705451 0.268726134 0.429755172 FBgn0039378 alpha4GT2 alpha4GT2 http://flybase.org/reports/FBgn0039378 protein_coding_gene "galactosyltransferase activity ; GO:0008378 | inferred from sequence or structural similarity with HGNC:18149 alpha-1,4-N-acetylgalactosaminyltransferase activity ; GO:0035248 | inferred from direct assay" glycosphingolipid biosynthetic process ; GO:0006688 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:18149 "CG5878, alpha4GT2" "IPR007577:Glycosyltransferase, DXD sugar-binding motif, IPR007652:Alpha 1,4-glycosyltransferase domain, IPR029044:Nucleotide-diphospho-sugar transferases" CG5878 11-Aug-17 DroID_v2017_08 - - "Cele\fbxb-7, Cele\Y20C6A.4" "Xtro\a4gnt, Xtro\a4galt, Xtro\LOC100493399" "Mmus\A4gnt, Mmus\A4galt" "Hsap\A4GNT, Hsap\A4GALT" FBgn0040255 Ugt86De Ugt86De http://flybase.org/reports/FBgn0040255 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG6653, AC 006491E, Ugt86De, CG6653-PA, Ugt86DE" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG6653 11-Aug-17 DroID_v2017_08 "Drer\ugt2a4, Drer\ugt2b3, Drer\ugt5c2, Drer\ugt2a5, Drer\ugt5b1, Drer\ugt1b7, Drer\ugt1b3, Drer\ugt1ab, Drer\ugt5f1, Drer\ugt5c3, Drer\ugt5g2, Drer\ugt2a2, Drer\ugt2b1, Drer\ugt2b6, Drer\ugt2b5, Drer\ugt5e1, Drer\ugt5a5, Drer\ugt2a3, Drer\ugt2a1, Drer\ugt5b2, Drer\ugt5g1, Drer\ugt5a4, Drer\ugt5b4, Drer\ugt1b4, Drer\ugt5a1, Drer\ugt5b6, Drer\ugt1b2, Drer\ugt5a2, Drer\ugt1b5, Drer\ugt8, Drer\ugt5d1, Drer\ugt2a6, Drer\ugt5c1, Drer\ugt5b3, Drer\zgc:172315" Scer\ATG26 "Cele\ugt-46, Cele\ugt-18, Cele\ugt-5, Cele\ugt-24, Cele\ugt-44, Cele\ugt-59, Cele\ugt-6, Cele\ugt-28, Cele\ugt-47, Cele\C03A7.12, Cele\ugt-33, Cele\ugt-36, Cele\ugt-63, Cele\ugt-39, Cele\ugt-64, Cele\ugt-34, Cele\ugt-53, Cele\ugt-48, Cele\ugt-37, Cele\ugt-12, Cele\ugt-14, Cele\ugt-43, Cele\ugt-10, Cele\ugt-31, Cele\ugt-22, Cele\ugt-13, Cele\ugt-41, Cele\ugt-45, Cele\ugt-50, Cele\ugt-65, Cele\K04A8.10, Cele\ugt-62, Cele\ugt-30, Cele\C03A7.13, Cele\ugt-35, Cele\F54C1.1, Cele\ugt-17, Cele\ugt-55, Cele\ugt-21, Cele\ugt-29, Cele\C23G10.6, Cele\ugt-23, Cele\ugt-40, Cele\ugt-16, Cele\ugt-56, Cele\ugt-19, Cele\ugt-49, Cele\ugt-15, Cele\ugt-9, Cele\ugt-38, Cele\ugt-52, Cele\ugt-27, Cele\H23N18.4, Cele\ugt-32, Cele\ugt-20, Cele\ugt-7, Cele\ugt-11, Cele\ugt-26, Cele\Y43D4A.2, Cele\F10D2.8, Cele\ugt-2, Cele\ugt-42, Cele\ugt-60, Cele\ugt-61, Cele\ugt-54, Cele\ugt-51, Cele\ugt-25, Cele\ugt-58, Cele\ugt-4, Cele\ugt-8, Cele\ugt-1, Cele\ugt-3, Cele\C55H1.1" "Xtro\ugt3a2, Xtro\ugt8, Xtro\ugt2b4, Xtro\ugt2a1, Xtro\ugt1a6" "Mmus\Ugt1a10, Mmus\Ugt8a, Mmus\Ugt1a2, Mmus\Ugt2b38, Mmus\Ugt2a1, Mmus\Ugt2b1, Mmus\Ugt2b5, Mmus\Ugt2a3, Mmus\Ugt3a2, Mmus\Ugt1a7c, Mmus\Ugt3a1, Mmus\Ugt2a2, Mmus\Ugt2b37, Mmus\Ugt1a6b, Mmus\Ugt2b35, Mmus\Ugt1a1, Mmus\Ugt1a9, Mmus\Ugt2b34, Mmus\Ugt1a5, Mmus\Ugt2b36" "Hsap\UGT8, Hsap\UGT2B11, Hsap\UGT2B7, Hsap\UGT3A1, Hsap\UGT1A4, Hsap\UGT1A5, Hsap\UGT2B10, Hsap\UGT2B28, Hsap\UGT1A10, Hsap\UGT1A9, Hsap\UGT1A6, Hsap\UGT1A1, Hsap\UGT2A2, Hsap\UGT1A3, Hsap\UGT1A7, Hsap\UGT2A3, Hsap\UGT2B4, Hsap\UGT3A2, Hsap\UGT2B17, Hsap\UGT2B15, Hsap\UGT1A8" viable FBgn0001092 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2 http://flybase.org/reports/FBgn0001092 - protein_coding_gene NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR006424 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006424 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ; GO:0004365 | inferred from direct assay "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006424, InterPro:IPR020828, InterPro:IPR020829, InterPro:IPR020830, InterPro:IPR020831 glucose metabolic process ; GO:0006006 | inferred from electronic annotation with InterPro:IPR006424 glycolytic process ; GO:0006096 | inferred from expression pattern" lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "GAPDH II, CG8893, GADPH, Gapdh-2, GAPDH, Gapd, Gapdh, GA3PDH, Gapdh13F, Gapdh2, GAPDH2, GAP" "IPR006424:Glyceraldehyde-3-phosphate dehydrogenase, type I, IPR020828:Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain, IPR020829:Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, IPR020830:Glyceraldehyde 3-phosphate dehydrogenase, active site, IPR020831:Glyceraldehyde/Erythrose phosphate dehydrogenase family, IPR016040:NAD(P)-binding domain" CG8893 11-Aug-17 DroID_v2017_08 "Drer\gapdhs, Drer\gapdh" "Scer\TDH2, Scer\TDH1, Scer\TDH3" "Cele\gpd-2, Cele\gpd-1, Cele\gpd-4, Cele\gpd-3" Xtro\gapdh "Mmus\Gapdhs, Mmus\Gapdh-ps15, Mmus\Gapdh, Mmus\Pnmal2" "Hsap\PNMAL2, Hsap\GAPDHS, Hsap\GAPDH" adult stage "viable,fertile" FBgn0011829 Ret Ret oncogene http://flybase.org/reports/FBgn0011829 "FBgn0022789, FBgn0032930, FBgn0032931" protein_coding_gene "protein tyrosine kinase activity ; GO:0004713 | inferred from electronic annotation with InterPro:IPR020635 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with HGNC:9967 transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from sequence or structural similarity protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement integrin binding ; GO:0005178 | inferred from physical interaction with mys" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR020635 signal transduction ; GO:0007165 | inferred from sequence or structural similarity actin filament organization ; GO:0007015 | inferred from mutant phenotype dendrite development ; GO:0016358 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of cell-matrix adhesion ; GO:0001954 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity dendrite ; GO:0030425 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:9967 "MEN2, dRet, dRET, RET, Dret, CG14396, CG1061, ret, D-ret, DmHD-59, DRET, Reto, HD-59, Ret, DRet, DmRet, dret" "IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG14396 11-Aug-17 DroID_v2017_08 "Drer\kdr, Drer\styk1, Drer\fgfrl1b, Drer\ret, Drer\csf1rb, Drer\kita, Drer\fgfr4, Drer\pdgfrb, Drer\kitb, Drer\fgfrl1a, Drer\si:ch73-206d17.1, Drer\kdrl, Drer\LOC569566, Drer\flt4, Drer\fgfr1a, Drer\si:ch211-167j9.5, Drer\si:dkey-14o18.6, Drer\fgfr2, Drer\csf1ra, Drer\tek, Drer\pdgfra, Drer\pdgfrl, Drer\flt3, Drer\fgfr3, Drer\tie1, Drer\flt1" - "Cele\C24G6.2, Cele\kin-9, Cele\egl-15, Cele\F09G2.1" "Xtro\styk1, Xtro\tek, Xtro\flt1, Xtro\fgfr1, Xtro\fgfr3, Xtro\flt4, Xtro\fgfrl1, Xtro\tie1, Xtro\fgfr2, Xtro\pdgfra, Xtro\pdgfrl.2, Xtro\pdgfrl, Xtro\ret, Xtro\csf1r, Xtro\fgfr4, Xtro\kdr" "Mmus\Styk1, Mmus\Fgfrl1, Mmus\Flt4, Mmus\Fgfr4, Mmus\Fgfr2, Mmus\Fgfr1, Mmus\Flt3, Mmus\Fgfr3, Mmus\Tek, Mmus\Pdgfrb, Mmus\Tie1, Mmus\Ret, Mmus\Kdr, Mmus\Pdgfra, Mmus\Pdgfrl, Mmus\Kit, Mmus\Csf1r, Mmus\Flt1" "Hsap\CSF1R, Hsap\FGFR3, Hsap\FLT3, Hsap\PDGFRL, Hsap\KIT, Hsap\KDR, Hsap\RET, Hsap\TIE1, Hsap\PDGFRA, Hsap\FGFR1, Hsap\FGFR2, Hsap\FLT1, Hsap\FLT4, Hsap\PDGFRB, Hsap\STYK1, Hsap\FGFRL1, Hsap\TEK, Hsap\FGFR4" " embryonic stage | stage >=12 , embryonic stage | stage 12 , embryonic stage | stage 11-12 , embryonic stage | stage 16 , embryonic stage | late , embryonic stage | stage 13 , embryonic stage | stage 8-11 , embryonic stage | stage >=13 , embryonic stage | cellular blastoderm , larval stage , pupal stage , embryonic stage , adult stage && oogenesis stage , larval stage | third instar " " embryonic brain | restricted

, anterior midgut proper primordium

, neuroblast | subset

, posterior midgut proper primordium

, embryonic proventricular ganglion

, larval labral segment sense organ | precursor

, dorsal organ | precursor

, embryonic peripheral nervous system | restricted

, yolk sac

, embryonic frontal ganglion

, ventral nerve cord | restricted

, labral nerve | precursor

, terminal organ | precursor

, midgut imaginal island

, embryonic esophageal ganglion

,

restricted , Bolwig's organ

, nurse cell

, embryonic stomatogastric nervous system

, eye disc | restricted

, embryonic Malpighian tubule

" "visible,partially lethal - majority die,decreased cell death,viable,size defective,lethal - all die before end of pupal stage,somatic clone,lethal,heat sensitive" "eye,ommatidium,eye disc,cone cell,wing vein,anterior crossvein,genital arch,wing disc,retina,supernumerary,inter-ommatidial cell,trichogen cell,scutellum | pupal stage,mesothoracic tergum,somatic clone,wing,ectopic,indirect flight muscle" FBgn0039669 ND-20L NADH dehydrogenase (ubiquinone) 20 kDa subunit-like http://flybase.org/reports/FBgn0039669 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR006138 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR006138 quinone binding ; GO:0048038 | inferred from electronic annotation with InterPro:IPR006138 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O75251" "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O75251 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O75251 "CG2014, NUKM, ND-20L, ND20-like" "IPR006137:NADH:ubiquinone oxidoreductase-like, 20kDa subunit, IPR006138:NADH-ubiquinone oxidoreductase, 20 Kd subunit" CG2014 11-Aug-17 DroID_v2017_08 Drer\ndufs7 - Cele\nduf-7 Xtro\ndufs7 Mmus\Ndufs7 Hsap\NDUFS7 viable FBgn0042103 CG18746 - http://flybase.org/reports/FBgn0042103 protein_coding_gene - - - CG18746 "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG18746 11-Aug-17 DroID_v2017_08 "Drer\zgc:110626, Drer\arrdc1b, Drer\arrdc3b, Drer\arrdc2, Drer\arrdc1a, Drer\arrdc3a, Drer\txnipb, Drer\zgc:110353, Drer\LOC799768, Drer\txnipa, Drer\si:ch211-130m23.2" "Scer\ROG3, Scer\CSR2, Scer\ALY2, Scer\ART5, Scer\ALY1, Scer\RIM8, Scer\ECM21, Scer\LDB19, Scer\ROD1" "Cele\arrd-24, Cele\rnh-1.2, Cele\arrd-17, Cele\arrd-19, Cele\arrd-23, Cele\arrd-1, Cele\arrd-16, Cele\arrd-3, Cele\arrd-11, Cele\arrd-25, Cele\arrd-8, Cele\arrd-27, Cele\arrd-4, Cele\arrd-2, Cele\arrd-6, Cele\arrd-13, Cele\arrd-9, Cele\arrd-18, Cele\arrd-15, Cele\arrd-12, Cele\arrd-14, Cele\arrd-22, Cele\arrd-7, Cele\arrd-5" "Xtro\arrdc3, Xtro\arrdc2, Xtro\txnip, Xtro\arrdc4" "Mmus\Arrdc3, Mmus\Arrdc2, Mmus\Arrdc5, Mmus\Arrdc1, Mmus\Arrdc4, Mmus\Txnip" "Hsap\ARRDC4, Hsap\ARRDC5, Hsap\TXNIP, Hsap\ARRDC1, Hsap\ARRDC2, Hsap\ARRDC3" viable FBgn0035042 CG3640 - http://flybase.org/reports/FBgn0035042 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model CG3640 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG3640 11-Aug-17 DroID_v2017_08 "Drer\glipr1b, Drer\crispld1a, Drer\pi15a, Drer\pi15b, Drer\glipr2, Drer\LOC100536500, Drer\crispld1b, Drer\crispld2, Drer\r3hdml, Drer\glipr2l, Drer\LOC101883528" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\scl-18, Cele\scl-11, Cele\scl-10, Cele\scl-3, Cele\scl-21, Cele\scl-2, Cele\scl-17, Cele\scl-14, Cele\scl-12, Cele\scl-15, Cele\scl-8, Cele\scl-23, Cele\scl-1, Cele\vap-2, Cele\scl-13, Cele\scl-7, Cele\scl-19, Cele\scl-20, Cele\scl-9, Cele\scl-5, Cele\scl-6" "Xtro\crisp1, Xtro\pi15, Xtro\MGC108118, Xtro\crispld2, Xtro\crisp3, Xtro\r3hdml, Xtro\crisp2, Xtro\glipr2" "Mmus\Glipr1, Mmus\Crisp3, Mmus\Glipr1l1, Mmus\Crisp2, Mmus\Crispld1, Mmus\Crispld2, Mmus\Pi15, Mmus\Crisp1, Mmus\R3hdml, Mmus\Glipr1l2, Mmus\Pi16, Mmus\Crisp4, Mmus\Glipr2, Mmus\Clec18a" "Hsap\PI16, Hsap\CRISP2, Hsap\GLIPR1L1, Hsap\CRISPLD2, Hsap\GLIPR1, Hsap\GLIPR2, Hsap\CLEC18A, Hsap\CRISPLD1, Hsap\CLEC18B, Hsap\R3HDML, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\CRISP1, Hsap\PI15" viable FBgn0039129 RpS19b Ribosomal protein S19b http://flybase.org/reports/FBgn0039129 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001266, InterPro:IPR018277 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001266, InterPro:IPR018277 cytoplasmic translation ; GO:0002181 | traceable author statement ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000194951" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001266, InterPro:IPR018277 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement" "CG5338, BcDNA:SD22440, RpS19b, RpS19" "IPR018277:Ribosomal protein S19e, conserved site, IPR001266:Ribosomal protein S19e, IPR011991:Winged helix-turn-helix DNA-binding domain" CG5338 11-Aug-17 DroID_v2017_08 Drer\rps19 "Scer\RPS19A, Scer\RPS19B" Cele\rps-19 Xtro\rps19 Mmus\Rps19 Hsap\RPS19 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0010019 Cyp4g1 Cytochrome P450-4g1 http://flybase.org/reports/FBgn0010019 "FBgn0011757, FBgn0023539, FBgn0044782" protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 lipid metabolic process ; GO:0006629 | inferred from mutant phenotype" - "4g1, EG:165H7.1, CG3972, scgamma, T1, P450, ASC-T1, P-450, P-450-A, P450-A, Cyt-P450-A1, anon-WO0140519.102, Cyp4g1, cyp4g1, P450A, CYP4G1" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG3972 11-Aug-17 DroID_v2017_08 "Drer\cyp19a1a, Drer\cyp46a1.4, Drer\cyp4v7, Drer\cyp19a1b, Drer\LOC100329425, Drer\cyp46a1.2, Drer\cyp4f3, Drer\cyp46a1.3, Drer\cyp26a1, Drer\cyp4t8, Drer\cyp26c1, Drer\cyp20a1, Drer\cyp4v8, Drer\cyp46a1.1, Drer\cyp26b1" "Scer\DIT2, Scer\ERG5" "Cele\cyp-32B1, Cele\cyp-33C4, Cele\cyp-37A1, Cele\cyp-32A1, Cele\cyp-42A1, Cele\cyp-37B1, Cele\cyp-29A2, Cele\cyp-29A3, Cele\cyp-31A3, Cele\cyp-31A2, Cele\cyp-29A4" "Xtro\cyp4v2, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\cyp4b1, Xtro\cyp19a1, Xtro\mgc108213, Xtro\cyp20a1, Xtro\cyp26b1, Xtro\LOC100487918, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\cyp4f2, Xtro\cyp26a1" "Mmus\Cyp26a1, Mmus\Cyp4f40, Mmus\Cyp20a1, Mmus\Cyp4a31, Mmus\Cyp4f16, Mmus\Cyp19a1, Mmus\Cyp4f13, Mmus\Cyp4a14, Mmus\Cyp4v3, Mmus\Cyp4a12a, Mmus\Cyp46a1, Mmus\Cyp4f15, Mmus\Cyp4f39, Mmus\Cyp4x1, Mmus\Cyp26b1, Mmus\Cyp4f37, Mmus\Cyp4f17, Mmus\Cyp4a30b, Mmus\Cyp8b1, Mmus\Cyp4a10, Mmus\Cyp4a12b, Mmus\Cyp4a29, Mmus\Cyp4a32, Mmus\Cyp26c1, Mmus\Cyp4f18, Mmus\Cyp4b1, Mmus\Cyp4f14" "Hsap\CYP4Z1, Hsap\CYP4A22, Hsap\CYP26A1, Hsap\CYP4F12, Hsap\CYP26C1, Hsap\CYP4F2, Hsap\CYP46A1, Hsap\CYP4B1, Hsap\CYP4F8, Hsap\CYP19A1, Hsap\CYP4F22, Hsap\CYP4A11, Hsap\CYP26B1, Hsap\CYP4V2, Hsap\CYP8B1, Hsap\CYP20A1, Hsap\CYP4F11, Hsap\CYP4X1, Hsap\CYP4F3" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,viable" FBgn0039274 CG11920 - http://flybase.org/reports/FBgn0039274 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000506837 rRNA primary transcript binding ; GO:0042134 | inferred from biological aspect of ancestor with PANTHER:PTN000506776 cellular response to starvation ; GO:0009267 | inferred from expression pattern rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000506776 nucleolus ; GO:0005730 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay Mpp10 complex ; GO:0034457 | inferred from biological aspect of ancestor with PANTHER:PTN000506837 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000506837 CG11920 "IPR007109:Brix domain, IPR004154:Anticodon-binding" CG11920 11-Aug-17 DroID_v2017_08 "Drer\ndor1, Drer\imp4" Scer\IMP4 "Cele\ZK795.3, Cele\fre-1" "Xtro\imp4, Xtro\ndor1" "Mmus\Ndor1, Mmus\Imp4" Hsap\IMP4 FBgn0013770 Cp1 Cysteine proteinase-1 http://flybase.org/reports/FBgn0013770 FBgn0019814 protein_coding_gene peptidase activity ; GO:0008233 | inferred from direct assay cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 proteolysis ; GO:0006508 | inferred from direct assay inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 fusome ; GO:0045169 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay "Dcp-1, cp1, CT20780, Dcp1, CG6692, CP1, fs(2)50Ca, DCP1, CysP-1, Cp1, CatL, Cath L, CTSL, CATL_DROME, CL" "IPR000169:Cysteine peptidase, cysteine active site, IPR000668:Peptidase C1A, papain C-terminal, IPR013128:Peptidase C1A, IPR013201:Cathepsin propeptide inhibitor domain (I29), IPR025661:Cysteine peptidase, asparagine active site, IPR025660:Cysteine peptidase, histidine active site" CG6692 11-Aug-17 DroID_v2017_08 "Drer\ctsll, Drer\si:dkey-239j18.2, Drer\ctsz, Drer\ctsf, Drer\si:dkey-228a15.1, Drer\ctsbb, Drer\si:dkey-269i1.4, Drer\ctso, Drer\si:dkey-269i1.3, Drer\ctsla, Drer\ctss2.2, Drer\wu:fa26c03, Drer\si:dkey-183k8.2, Drer\zgc:110239, Drer\zgc:103438, Drer\ctsk, Drer\ctss1, Drer\LOC100536033, Drer\zgc:174153, Drer\ctsl.1, Drer\ctss2.1, Drer\ctslb, Drer\cts12, Drer\LOC100333521, Drer\MGC174857, Drer\ctsh, Drer\zgc:174855, Drer\si:dkey-267n13.1, Drer\MGC174155, Drer\si:dkey-26g8.4, Drer\ctsc, Drer\si:dkey-239j18.3, Drer\ctsba" - "Cele\K02E7.10, Cele\tag-196, Cele\R09F10.1, Cele\cpl-1" "Xtro\ctsh, Xtro\LOC100490139, Xtro\ctss, Xtro\ctsv, Xtro\ctsc, Xtro\ctsb, Xtro\LOC100498238, Xtro\ctsz, Xtro\ctsl, Xtro\ctsw" "Mmus\BC051665, Mmus\Ctsz, Mmus\Ctla2a, Mmus\Ctsw, Mmus\Cts7, Mmus\Cts8, Mmus\Ctsq, Mmus\Ctsll3, Mmus\Cts3, Mmus\Ctsr, Mmus\Ctsj, Mmus\4930486L24Rik, Mmus\Cts6, Mmus\Ctsh, Mmus\Ctso, Mmus\Ctla2b, Mmus\Ctsc, Mmus\Ctsl, Mmus\Ctsk, Mmus\Ctss, Mmus\Ctsf, Mmus\Ctsm, Mmus\Ctsb" "Hsap\CTSK, Hsap\CTSZ, Hsap\CTSV, Hsap\CTSW, Hsap\CTSB, Hsap\CTSO, Hsap\CTSS, Hsap\CTSC, Hsap\CTSH, Hsap\CTSL, Hsap\CTSF" "viable,increased cell death,fertile,visible,recessive,female sterile,non-suppressor of variegation,dominant,male fertile,body color defective" "female germline cell,egg,wing,adult abdominal segment 1,adult abdominal segment 2,adult abdominal segment 3,adult abdominal segment 4,adult abdominal segment 5" FBgn0032292 EMC3 ER Membrane protein Complex 3 http://flybase.org/reports/FBgn0032292 protein_coding_gene molecular_function ; GO:0003674 | no biological data available rhabdomere development ; GO:0042052 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype protein folding in endoplasmic reticulum ; GO:0034975 | inferred from biological aspect of ancestor with PANTHER:PTN000319097 wound healing ; GO:0042060 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN000319097 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG6750, EMC3, dPob" "IPR008568:ER membrane protein complex subunit 3, IPR002809:Integral membrane protein EMC3/TMCO1-like" CG6750 11-Aug-17 DroID_v2017_08 "Drer\emc3, Drer\zgc:86609" Scer\EMC3 Cele\emc-3 "Xtro\emc3, Xtro\tmem111" Mmus\Emc3 Hsap\EMC3 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053329 Sp212 Serine-peptidase 212 http://flybase.org/reports/FBgn0053329 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 response to bacterium ; GO:0009617 | inferred from expression pattern response to fungus ; GO:0009620 | inferred from expression pattern" cellular_component ; GO:0005575 | no biological data available "Sp212, CG33329, SP212, ORE-5" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR031986:Serine protease gd, N-terminal domain" CG33329 11-Aug-17 DroID_v2017_08 - - "Cele\svh-1, Cele\try-5" - - - DRSC22930 K -1.067276024 0.37768832 -0.581534434 0.364136404 1.584074022 0.406044151 FBgn0038461 CG3678 - http://flybase.org/reports/FBgn0038461 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available microtubule associated complex ; GO:0005875 | inferred from direct assay "CG3678, RE62710p" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG3678 11-Aug-17 DroID_v2017_08 Drer\emc2 Scer\EMC2 Cele\emc-2 Xtro\emc2 Mmus\Emc2 Hsap\EMC2 FBgn0034577 cpa capping protein alpha http://flybase.org/reports/FBgn0034577 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with cpb negative regulation of filopodium assembly ; GO:0051490 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype negative regulation of actin filament polymerization ; GO:0030837 | inferred from mutant phenotype regulation of filopodium assembly ; GO:0051489 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of lamellipodium assembly ; GO:0010591 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with cpb barbed-end actin filament capping ; GO:0051016 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype barbed-end actin filament capping ; GO:0051016 | inferred from sequence or structural similarity adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay dynactin complex ; GO:0005869 | inferred from sequence or structural similarity apical plasma membrane ; GO:0016324 | inferred from direct assay WASH complex ; GO:0071203 | inferred from sequence or structural similarity with UniProtKB:P52907 microtubule associated complex ; GO:0005875 | inferred from direct assay F-actin capping protein complex ; GO:0008290 | inferred from direct assay "scrd, CG10540, miro, cpa, Cpa, CapZalpha, Cap1, cpalpha" "IPR002189:F-actin-capping protein subunit alpha, IPR017865:F-actin capping protein, alpha subunit, conserved site" CG10540 11-Aug-17 DroID_v2017_08 "Drer\capza1b, Drer\capza1a" Scer\CAP1 Cele\cap-1 "Xtro\capza2, Xtro\capza1" "Mmus\Capza1, Mmus\Capza3, Mmus\Capza2" "Hsap\CAPZA3, Hsap\CAPZA2, Hsap\CAPZA1" "increased cell death,heat sensitive,decreased cell death,increased cell growth,lethal,recessive,visible,somatic clone,cell lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage" "wing disc,wing hinge primordium,posterior compartment,heat sensitive,eye,somatic clone,actin cytoskeleton & eye disc | somatic clone,wing,macrochaeta,egg chamber,germline clone,oocyte,oocyte nucleus,follicle cell,filopodium | supernumerary,actin cytoskeletonHml.PG" FBgn0267348 LanB2 Laminin B2 http://flybase.org/reports/FBgn0267348 protein_coding_gene - extracellular matrix assembly ; GO:0085029 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype inferred from genetic interaction with Gyc76C substrate adhesion-dependent cell spreading ; GO:0034446 | inferred from direct assay basement membrane assembly ; GO:0070831 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from direct assay endodermal digestive tract morphogenesis ; GO:0061031 | inferred from mutant phenotype basement membrane ; GO:0005604 | inferred from direct assay basal lamina ; GO:0005605 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from direct assay basement membrane ; GO:0005604 | inferred from sequence or structural similarity endomembrane system ; GO:0012505 | inferred from direct assay "LanB2, knod, l(3)67BDb, CG3322, lanB2, CT11145, LM-B2/gamma, gamma1, LAMB2A, DROLAMB2A, lamB2, anon-EST:fe2H3, Lam-B2, LMG1" "IPR008979:Galactose-binding domain-like, IPR000034:Laminin IV, IPR002049:Laminin EGF domain, IPR008211:Laminin, N-terminal, IPR031082:Laminin subunit gamma, IPR000742:EGF-like domain" CG3322 11-Aug-17 DroID_v2017_08 "Drer\ush2a, Drer\lamc1, Drer\lama3, Drer\LOC567928, Drer\ntn5, Drer\ntn1b, Drer\ntn2, Drer\si:dkey-202e22.2, Drer\lama2, Drer\lama1, Drer\lama5, Drer\lamc3, Drer\lama4" - "Cele\C23H4.6, Cele\lam-3, Cele\lam-2, Cele\epi-1" "Xtro\lama1, Xtro\ntn1, Xtro\lamb3, Xtro\lama3, Xtro\ntn3, Xtro\lama4, Xtro\lamc1, Xtro\lama5, Xtro\lamc2, Xtro\lama2" "Mmus\Ntn3, Mmus\Ush2a, Mmus\Lamc2, Mmus\Lama3, Mmus\Lama5, Mmus\Lama2, Mmus\Lamc3, Mmus\Lama4, Mmus\Ntng1, Mmus\Lama1, Mmus\Ntn4, Mmus\Lamc1, Mmus\Lamb3, Mmus\Ntn1" "Hsap\LAMA3, Hsap\LAMC3, Hsap\LAMC2, Hsap\NTNG1, Hsap\LAMA2, Hsap\LAMA1, Hsap\NTN4, Hsap\NTN1, Hsap\NTN3, Hsap\USH2A, Hsap\LAMC1, Hsap\LAMB3, Hsap\LAMA5, Hsap\LAMA4" " embryonic stage | stage 11-12 , embryonic stage , embryonic stage | late , embryonic stage | stage >12 " " head mesoderm

, somatic mesoderm

, ventral nerve cord

, ectoderm

, interface glial cell

, embryonic/larval midgut

, glial cell | lateral

, hemocyte

, ventral midline

, embryonic/larval fat body

, sense organ

, embryonic brain

, visceral mesoderm

" " embryonic stage | stage 13-15 , embryonic stage | 10-13 hr " " segmental nerve

, intersegmental nerve

, embryonic/larval digestive system

, myoblast &&of larval muscle system

, epidermis

, neuropil associated CNS glial cell

" FBgn0030803 CG4880 - http://flybase.org/reports/FBgn0030803 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR010448, InterPro:IPR030553" - nuclear envelope ; GO:0005635 | inferred from electronic annotation with InterPro:IPR030553 endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR030553 CG4880 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR030553:Torsin-like protein, IPR010448:Torsin" CG4880 11-Aug-17 DroID_v2017_08 "Drer\tor4ab, Drer\tor1, Drer\tor2a, Drer\tor1l1, Drer\tor3a, Drer\tor1l2, Drer\tor1l3, Drer\tor4aa" - "Cele\ooc-5, Cele\tor-1, Cele\tor-2" - "Mmus\Tor4a, Mmus\Tor1b, Mmus\Tor1a, Mmus\Tor3a, Mmus\Tor2a" "Hsap\TOR1B, Hsap\TOR2A, Hsap\TOR1A, Hsap\TOR4A, Hsap\TOR3A" viable FBgn0025716 Bap55 Brahma associated protein 55kD http://flybase.org/reports/FBgn0025716 FBgn0034216 protein_coding_gene transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 "dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from sequence or structural similarity with SGD:S000003617 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype histone exchange ; GO:0043486 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype positive regulation of gene silencing by miRNA ; GO:2000637 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from direct assay" npBAF complex ; GO:0071564 | inferred from electronic annotation with InterPro:IPR029912 brahma complex ; GO:0035060 | inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay PBAF complex ; GO:0070604 | inferred from direct assay "BAP55, BAP47, CG6546, bap55, Bap55, BAF53, Baf53, Arp4, ARP4" "IPR004000:Actin family, IPR029912:Actin-like protein 6A" CG6546 11-Aug-17 DroID_v2017_08 "Drer\actl6a, Drer\actl6b" "Scer\ARP4, Scer\ARP7, Scer\ARP1" Cele\swsn-6 Xtro\actl6a "Mmus\Actl6b, Mmus\Actl6a" "Hsap\ACTL6A, Hsap\ACTL6B" "lethal,partially lethal - majority die,visible,neuroanatomy defective,recessive,decreased cell number" "embryonic/larval brain,mesothoracic tergum,adult antennal lobe projection neuron DL1 adPN" DRSC07000 IE -0.232029448 -1.869431272 -0.390115784 -3.401777305 -0.213797607 -1.31363322 FBgn0086656 shrb shrub http://flybase.org/reports/FBgn0086656 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with borr vacuolar transport ; GO:0007034 | inferred from electronic annotation with InterPro:IPR005024 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype negative regulation of growth of symbiont in host ; GO:0044130 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype neuronal cell body ; GO:0043025 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay proximal dendrite ; GO:1990635 | inferred from direct assay ESCRT III complex ; GO:0000815 | inferred from sequence or structural similarity with SGD:S000004015 contractile ring ; GO:0070938 | inferred from direct assay multivesicular body ; GO:0005771 | inferred from direct assay "Vps32, CG8055, vps32/snf7, Snf7/Vps32, anon-WO0118547.180, shrub, shrb, vps32, ESCRT-III, Snf7, Shrb, DmSNF2, Dvps32, Shrub, ESCRT" IPR005024:Snf7 family CG8055 11-Aug-17 DroID_v2017_08 "Drer\chmp4ba, Drer\chmp4c, Drer\chmp4bb" Scer\SNF7 "Cele\vps-32.1, Cele\T24B8.2, Cele\R12C12.5, Cele\vps-32.2" "Xtro\chmp4b, Xtro\chmp4c" "Mmus\Chmp4c, Mmus\Chmp4b" "Hsap\FBXO34, Hsap\CHMP4C, Hsap\CHMP4B, Hsap\CHMP4A" DRSC07061 I -0.58697176 -1.58324944 0.887668018 -1.351358156 -0.861500412 -1.497838754 FBgn0044030 mRpS14 mitochondrial ribosomal protein S14 http://flybase.org/reports/FBgn0044030 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with protein_id:CAB16601 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with protein_id:CAB16601 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with protein_id:CAB16601 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "MRP-S14, S14, CG12211, cg12211, MrpS14, CG32531, mRpS14" IPR001209:Ribosomal protein S14 CG32531 11-Aug-17 DroID_v2017_08 Drer\mrps14 Scer\MRP2 Cele\mrps-14 Xtro\mrps14 Mmus\Mrps14 Hsap\MRPS14 "viable,visible" trichogen cell FBgn0052669 CG32669 - http://flybase.org/reports/FBgn0052669 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "CG32669, dSLC5A4" IPR001734:Sodium/solute symporter CG32669 11-Aug-17 DroID_v2017_08 "Drer\slc5a9, Drer\slc5a12, Drer\slc5a6b, Drer\slc5a8l, Drer\slc5a5, Drer\slc5a8, Drer\slc5a6a" Scer\DUR3 "Cele\F52H2.4, Cele\ZK822.5" "Xtro\slc5a12, Xtro\slc5a5, Xtro\slc5a8, Xtro\slc5a2" "Mmus\Slc5a12, Mmus\Slc5a6, Mmus\Slc5a5, Mmus\Slc5a9, Mmus\Slc5a8" "Hsap\SLC5A5, Hsap\SLC5A9, Hsap\SLC5A6, Hsap\SLC5A12, Hsap\SLC5A8" viable FBgn0025725 alphaCOP Coat Protein (coatomer) alpha http://flybase.org/reports/FBgn0025725 - protein_coding_gene "structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR006692, InterPro:IPR010714" "intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000458798 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | non-traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000458798 cell morphogenesis ; GO:0000902 | inferred from mutant phenotype retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000458798 regulation of lipid storage ; GO:0010883 | inferred from direct assay intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000458798" COPI vesicle coat ; GO:0030126 | inferred from direct assay "alphaCOP, alpha-COP, alphaCop, CG7961" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR006692:Coatomer, WD associated region, IPR010714:Coatomer, alpha subunit, C-terminal, IPR017986:WD40-repeat-containing domain, IPR016391:Coatomer alpha subunit, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011990:Tetratricopeptide-like helical domain" CG7961 11-Aug-17 DroID_v2017_08 Drer\copa Scer\COP1 Cele\copa-1 Xtro\copa Mmus\Copa Hsap\COPA "lethal,viable,fertile" "onion stage spermatid,astral microtubule | malebam.THsimVP16,spindle microtubule | malebam.THsimVP16" DRSC08706 IE -0.51004758 1.82271904 1.387286071 -3.141692274 0.035042846 -1.329560631 FBgn0038855 CG5745 - http://flybase.org/reports/FBgn0038855 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 phagocytosis ; GO:0006909 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG5745 IPR000195:Rab-GTPase-TBC domain CG5745 11-Aug-17 DroID_v2017_08 "Drer\tbc1d22a, Drer\tbc1d22b, Drer\snw1" Scer\GYP1 "Cele\tbc-3, Cele\skp-1, Cele\tbck-1" "Xtro\snw1, Xtro\tbc1d22b, Xtro\tbc1d22a" "Mmus\Snw1, Mmus\Tbc1d22b, Mmus\Tbc1d22a" "Hsap\TBC1D22B, Hsap\TBC1D22A" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0033907 mRpS16 mitochondrial ribosomal protein S16 http://flybase.org/reports/FBgn0033907 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D3 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82915 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D3 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:P82915 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D3 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82915 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "147189_at, MRP-S16, CG8338, BcDNA:SD15809, mRpS16" "IPR000307:Ribosomal protein S16, IPR023803:Ribosomal protein S16 domain" CG8338 11-Aug-17 DroID_v2017_08 Drer\mrps16 Scer\MRPS16 Cele\mrps-16 Xtro\mrps16 Mmus\Mrps16 Hsap\MRPS16 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0033375 CG8078 - http://flybase.org/reports/FBgn0033375 protein_coding_gene tRNA binding ; GO:0000049 | inferred from sequence or structural similarity with UniProtKB:P53088 tRNA thio-modification ; GO:0034227 | inferred from sequence or structural similarity with UniProtKB:P53088 tRNA wobble uridine modification ; GO:0002098 | inferred from sequence or structural similarity with UniProtKB:P53088 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P53088 "anon-WO0118547.76, CG8078" "IPR000541:Cytoplasmic tRNA 2-thiolation protein 1, IPR011063:tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal, IPR012089:2-thiocytidine tRNA biosynthesis protein, TtcA, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR020554:Uncharacterised protein family UPF0021, conserved site, IPR032442:Cytoplasmic tRNA 2-thiolation protein 1, C-terminal" CG8078 11-Aug-17 DroID_v2017_08 Drer\ctu1 Scer\NCS6 "Cele\tut-2, Cele\tut-1" Xtro\ctu1 Mmus\Ctu1 Hsap\CTU1 "viable,visible" "tormogen cell,mesothoracic tergum" FBgn0037374 jagn jagunal http://flybase.org/reports/FBgn0037374 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from electronic annotation with InterPro:IPR013833 respiratory electron transport chain ; GO:0022904 | inferred from electronic annotation with InterPro:IPR013833 chaeta development ; GO:0022416 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype vitellogenesis ; GO:0007296 | inferred from mutant phenotype oocyte growth ; GO:0001555 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from mutant phenotype establishment of ER localization ; GO:0051686 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay "CG10978, jagn" "IPR009787:Protein jagunal, IPR013833:Cytochrome c oxidase, subunit III, 4-helical bundle" CG10978 11-Aug-17 DroID_v2017_08 "Drer\jagn1b, Drer\jagn1a" - Cele\K05C4.2 Xtro\jagn1 Mmus\Jagn1 Hsap\JAGN1 "lethal,recessive,partially lethal - majority die" "oocyte,germline clone,nurse cell,macrochaeta,somatic clone,microchaeta,wing margin bristle,endoplasmic reticulum & oocyte | germ-line clone,yolk granule & oocyte | germ-line clone,microvillus & oocyte | germ-line clone" FBgn0262716 Arp3 Actin-related protein 3 http://flybase.org/reports/FBgn0262716 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR015623 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with HGNC:170 ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from physical interaction with Arpc1 chaeta development ; GO:0022416 | inferred from mutant phenotype membrane tubulation ; GO:0097320 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity positive regulation of lamellipodium assembly ; GO:0010592 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype axonal fasciculation ; GO:0007413 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype inferred from genetic interaction with WASp positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from sequence or structural similarity with HGNC:170 cell morphogenesis ; GO:0000902 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype actin filament reorganization involved in cell cycle ; GO:0030037 | inferred from physical interaction with Arpc1 myoblast fusion ; GO:0007520 | inferred from mutant phenotype Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity lamellipodium ; GO:0030027 | inferred from direct assay Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with HGNC:170 actin filament ; GO:0005884 | inferred from sequence or structural similarity with EMBL:M81068 Arp2/3 protein complex ; GO:0005885 | non-traceable author statement "arp3, Arp66B, Arp3, schwachling, CG7558, ARP3, arp66B, Actr66B, anon-WO0172774.138, AcTr66B, arp66b" "IPR015623:Actin-related protein 3, metazoa, IPR004000:Actin family, IPR020902:Actin/actin-like conserved site" CG7558 11-Aug-17 DroID_v2017_08 "Drer\actr3, Drer\actr3b" Scer\ARP3 Cele\arx-1 Xtro\actr3 "Mmus\Actr3, Mmus\Actr3b" "Hsap\ACTR3C, Hsap\ACTR3, Hsap\ACTR3B" oogenesis stage | stage S9 nurse cell ring canal

FBgn0039087 CG10168 - http://flybase.org/reports/FBgn0039087 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG10168 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG10168 11-Aug-17 DroID_v2017_08 "Drer\ugt1b2, Drer\ugt2a6, Drer\ugt5e1, Drer\ugt5b1, Drer\ugt1ab, Drer\ugt5a5, Drer\ugt1b5, Drer\ugt5c3, Drer\ugt8, Drer\ugt5a4, Drer\ugt2a2, Drer\ugt2a5, Drer\ugt2b5, Drer\ugt5b4, Drer\ugt5b6, Drer\ugt5d1, Drer\ugt2b6, Drer\ugt5c1, Drer\ugt5g2, Drer\ugt1b3, Drer\ugt1b4, Drer\ugt5a2, Drer\ugt5g1, Drer\ugt5a1, Drer\ugt5b3, Drer\ugt2b3, Drer\ugt5c2, Drer\ugt1b7, Drer\ugt5f1, Drer\ugt5b2, Drer\ugt2b1, Drer\zgc:172315" Scer\ATG26 "Cele\ugt-18, Cele\ugt-59, Cele\ugt-49, Cele\ugt-39, Cele\Y43D4A.2, Cele\C55H1.1, Cele\C23G10.6, Cele\ugt-26, Cele\ugt-38, Cele\F10D2.8, Cele\ugt-48, Cele\ugt-1, Cele\ugt-22, Cele\ugt-21, Cele\C03A7.13, Cele\ugt-61, Cele\ugt-37, Cele\ugt-19, Cele\ugt-43, Cele\ugt-16, Cele\ugt-3, Cele\ugt-52, Cele\ugt-46, Cele\ugt-17, Cele\ugt-60, Cele\ugt-14, Cele\ugt-30, Cele\K04A8.10, Cele\ugt-42, Cele\ugt-34, Cele\ugt-54, Cele\ugt-8, Cele\ugt-45, Cele\ugt-32, Cele\ugt-7, Cele\ugt-41, Cele\ugt-56, Cele\ugt-36, Cele\ugt-25, Cele\ugt-58, Cele\ugt-29, Cele\ugt-13, Cele\ugt-65, Cele\ugt-35, Cele\ugt-15, Cele\ugt-20, Cele\ugt-4, Cele\ugt-44, Cele\ugt-47, Cele\ugt-62, Cele\H23N18.4, Cele\ugt-50, Cele\ugt-33, Cele\ugt-40, Cele\ugt-51, Cele\ugt-10, Cele\ugt-27, Cele\C03A7.12, Cele\ugt-23, Cele\ugt-11, Cele\ugt-12, Cele\ugt-55, Cele\ugt-53, Cele\ugt-6, Cele\ugt-31, Cele\ugt-2, Cele\F54C1.1, Cele\ugt-5, Cele\ugt-28, Cele\ugt-9, Cele\ugt-24" "Xtro\ugt1a6, Xtro\ugt3a2, Xtro\ugt8, Xtro\ugt2a1, Xtro\ugt2b4" "Mmus\Ugt2b37, Mmus\Ugt8a, Mmus\Ugt2a2, Mmus\Ugt2b1, Mmus\Ugt1a7c, Mmus\Ugt2a3, Mmus\Ugt2b35, Mmus\Ugt1a10, Mmus\Ugt2b38, Mmus\Ugt3a1, Mmus\Ugt1a1, Mmus\Ugt2b34, Mmus\Ugt1a6b, Mmus\Ugt2b36, Mmus\Ugt2a1, Mmus\Ugt1a2, Mmus\Ugt1a9, Mmus\Ugt2b5, Mmus\Ugt1a5, Mmus\Ugt3a2" "Hsap\UGT2B7, Hsap\UGT3A2, Hsap\UGT2B4, Hsap\UGT8, Hsap\UGT1A4, Hsap\UGT2A3, Hsap\UGT1A10, Hsap\UGT2B11, Hsap\UGT1A7, Hsap\UGT1A8, Hsap\UGT1A1, Hsap\UGT1A5, Hsap\UGT2A2, Hsap\UGT2B28, Hsap\UGT1A6, Hsap\UGT2B17, Hsap\UGT3A1, Hsap\UGT1A9, Hsap\UGT1A3, Hsap\UGT2B10, Hsap\UGT2B15" viable DRSC14198 I -2.540109312 0.618495356 0.034856365 -0.435100373 0.994190363 -1.174256007 FBgn0027087 HisRS Histidyl-tRNA synthetase http://flybase.org/reports/FBgn0027087 "FBgn0027288, FBgn0028314, FBgn0030934" protein_coding_gene "histidine-tRNA ligase activity ; GO:0004821 | inferred from electronic annotation with InterPro:IPR015807 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000738, InterPro:IPR015807 histidine-tRNA ligase activity ; GO:0004821 | traceable author statement" histidyl-tRNA aminoacylation ; GO:0006427 | inferred from electronic annotation with InterPro:IPR015807 mitochondrial translation ; GO:0032543 | inferred from biological aspect of ancestor with PANTHER:PTN000159004 histidyl-tRNA aminoacylation ; GO:0006427 | traceable author statement cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement "HRS, CG6335, HisRS, l(1)G0165, l(1)G0358, Harsl, Aats-his" "IPR000738:WHEP-TRS domain, IPR004154:Anticodon-binding, IPR004516:Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR009068:S15/NS1, RNA-binding, IPR015807:Histidine-tRNA ligase, IPR033656:Histidyl-anticodon-binding" CG6335 11-Aug-17 DroID_v2017_08 Drer\hars Scer\HTS1 Cele\hars-1 "Xtro\hars, Xtro\hars2" "Mmus\Hars, Mmus\Hars2" "Hsap\HARS, Hsap\HARS2" embryonic stage embryonic/larval muscle system

"lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die,some die during pupal stage" FBgn0029943 Atg5 Autophagy-related 5 http://flybase.org/reports/FBgn0029943 protein_coding_gene Atg8 ligase activity ; GO:0019776 | contributes_to inferred from sequence or structural similarity with SGD:S000006070 Atg8 ligase activity ; GO:0019776 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000315667 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000315667 glycophagy ; GO:0061723 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype macroautophagy ; GO:0016236 | inferred from sequence or structural similarity with SGD:S000006070 cellular response to nitrogen starvation ; GO:0006995 | inferred from biological aspect of ancestor with PANTHER:PTN000315667 macroautophagy ; GO:0016236 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagy ; GO:0006914 | inferred from sequence or structural similarity with UniProtKB:Q99J83 autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000315667 C-terminal protein lipidation ; GO:0006501 | inferred from biological aspect of ancestor with PANTHER:PTN000315667 nucleophagy ; GO:0044804 | inferred from biological aspect of ancestor with PANTHER:PTN000315667 Atg12-Atg5-Atg16 complex ; GO:0034274 | inferred from biological aspect of ancestor with PANTHER:PTN000315667 Atg12-Atg5-Atg16 complex ; GO:0034274 | inferred from sequence or structural similarity with SGD:S000006070 pre-autophagosomal structure membrane ; GO:0034045 | inferred from biological aspect of ancestor with PANTHER:PTN000315667 autophagosome ; GO:0005776 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q99J83 "Atg5, ATG5, CG1643, DmAtg5, atg5" IPR007239:Autophagy-related protein 5 CG1643 11-Aug-17 DroID_v2017_08 Drer\atg5 Scer\ATG5 Cele\atg-5 Xtro\atg5 Mmus\Atg5 Hsap\ATG5 pupal stage salivary gland

"viable,fertile,chemical sensitive,immune response defective,RU486 conditional" fat body FBgn0039595 AstA-R2 Allatostatin A receptor 2 http://flybase.org/reports/FBgn0039595 protein_coding_gene neuropeptide Y receptor activity ; GO:0004983 | inferred from electronic annotation with InterPro:IPR000611 allatostatin receptor activity ; GO:0008261 | inferred from sequence or structural similarity with AstA-R1 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model allatostatin receptor activity ; GO:0008261 | inferred from physical interaction with AstA G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with AstA-R1 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with AstA-R1 "CG10001, D.AlstR2, DAR-2, DAR, anon-WO0170980.116, anon-WO0170980.115, anon-WO0131005.7, DAR2, ASTR, AstA-R2, AR-2, Dar-2" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000611:Neuropeptide Y receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG10001 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-171h4.6, Drer\galr1a, Drer\cxcr4b, Drer\ccr12a, Drer\nmur3, Drer\zgc:194312, Drer\xcr1b.1, Drer\si:dkey-117a8.1, Drer\cntn1b, Drer\LOC100151078, Drer\LOC101884647, Drer\ccr7, Drer\galr1b, Drer\galr2b, Drer\LOC100006764, Drer\si:dkey-211g8.1, Drer\si:ch73-160i9.1, Drer\neo1a, Drer\prlh2r, Drer\si:dkey-42l23.7, Drer\LOC101884253, Drer\nmur1b, Drer\LOC101885604, Drer\taar14f, Drer\si:ch211-207g17.3, Drer\gpr19, Drer\si:ch211-240b21.5, Drer\cntn2, Drer\ccr8.1, Drer\ccr9a, Drer\si:ch73-160i9.3, Drer\cabz01093075.1, Drer\xcr1a.1, Drer\igsf9ba, Drer\ackr4b, Drer\LOC793148, Drer\hcrtr2, Drer\LOC793479, Drer\si:dkey-42l23.5, Drer\npy7r, Drer\cntn1a, Drer\kiss1rb, Drer\cxcr4a, Drer\LOC101882856, Drer\igsf9bb, Drer\LOC797181, Drer\ccdc141, Drer\LOC103908669, Drer\kiss1ra, Drer\ccr12b.2, Drer\ccr6a, Drer\si:dkey-202l22.3, Drer\cxcr2, Drer\ackr4a, Drer\nmur1a, Drer\ackr3a, Drer\cmklr1, Drer\xcr1b.2, Drer\sc:d217, Drer\ccr12b.1, Drer\ccr9b, Drer\ackr3b, Drer\zmp:0000001069" - "Cele\npr-24, Cele\npr-9, Cele\frpr-18, Cele\tkr-3" "Xtro\hcrtr2, Xtro\gpr19, Xtro\galr3, Xtro\galr2, Xtro\kissr2, Xtro\npy5r, Xtro\nmur2, Xtro\LOC100125055, Xtro\kiss1r, Xtro\galr1, Xtro\ltb4r2" "Mmus\Cxcr1, Mmus\Ccrl2, Mmus\Ccr6, Mmus\Hcrtr1, Mmus\Nmur1, Mmus\Kiss1r, Mmus\Ackr4, Mmus\Ccr10, Mmus\Cxcr6, Mmus\Hcrtr2, Mmus\Ccr9, Mmus\Ccdc141, Mmus\Ackr2, Mmus\Neo1, Mmus\Cxcr2, Mmus\Cxcr3, Mmus\Xcr1, Mmus\Ccr4, Mmus\Cxcr5, Mmus\Mtnr1b, Mmus\Cntn1, Mmus\Dcc, Mmus\Gnrhr, Mmus\Galr2, Mmus\Gpr19, Mmus\Cntn2, Mmus\Ackr3, Mmus\Galr1, Mmus\Ccr1, Mmus\Cxcr4, Mmus\Ccr7, Mmus\Ccr5, Mmus\Ccr3, Mmus\Ccr2, Mmus\Igsf9b, Mmus\Npy5r, Mmus\Cmklr1, Mmus\Cx3cr1, Mmus\Ccr8, Mmus\Nmur2, Mmus\Ccr1l1" "Hsap\NMUR2, Hsap\CCR3, Hsap\CCR5, Hsap\CNTN2, Hsap\XCR1, Hsap\CXCR5, Hsap\CCR4, Hsap\CXCR6, Hsap\CCR6, Hsap\CNTN1, Hsap\CCR10, Hsap\CCR8, Hsap\CCR9, Hsap\CXCR2, Hsap\NMUR1, Hsap\CCR7, Hsap\CCR1, Hsap\DCC, Hsap\GALR2, Hsap\CMKLR1, Hsap\KISS1R, Hsap\MTNR1B, Hsap\CCDC141, Hsap\CX3CR1, Hsap\ACKR3, Hsap\GPR19, Hsap\CXCR1, Hsap\CXCR4, Hsap\ACKR2, Hsap\GALR3, Hsap\CXCR3, Hsap\CCR2, Hsap\GNRHR, Hsap\IGSF9B, Hsap\GALR1, Hsap\CCRL2, Hsap\NEO1, Hsap\ACKR4, Hsap\HCRTR1" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0033457 Ntmt N-terminal methyltransferase http://flybase.org/reports/FBgn0033457 protein_coding_gene histone methyltransferase activity ; GO:0042054 | inferred from direct assay N-terminal protein N-methyltransferase activity ; GO:0071885 | inferred from direct assay N-terminal peptidyl-proline dimethylation ; GO:0018016 | inferred from direct assay N-terminal peptidyl-proline methylation ; GO:0035568 | inferred from direct assay histone methylation ; GO:0016571 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000297943 "CG1675, Ntmt, dNTMT" "IPR008576:Alpha-N-methyltransferase NTM1, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG1675 11-Aug-17 DroID_v2017_08 "Drer\si, Drer\mettl11b, Drer\ntmt1, Drer\asmt2" Scer\TAE1 Cele\homt-1 "Xtro\mettl11b, Xtro\ntmt1, Xtro\asmt, Xtro\asmtl" "Mmus\Mettl11b, Mmus\Asmt, Mmus\Ntmt1" "Hsap\METTL11B, Hsap\ASMT, Hsap\ASMTL, Hsap\NTMT1" viable FBgn0010315 CycD Cyclin D http://flybase.org/reports/FBgn0010315 - protein_coding_gene cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Cdk4 "cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR015451 cell proliferation ; GO:0008283 | inferred from genetic interaction with Cdk4 JAK-STAT cascade ; GO:0007259 | inferred from genetic interaction with upd1, Cdk4 cell growth ; GO:0016049 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR004367 "cyclinD, DmcycD, cycD, Cdi3, CDI3, cdi3, CG9096, CycD, dCycD, CYCD, Cyc D" "IPR004367:Cyclin, C-terminal domain, IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like, IPR015451:Cyclin D" CG9096 11-Aug-17 DroID_v2017_08 "Drer\ccnd2a, Drer\ccnd2b, Drer\si:ch211-152f23.5, Drer\ccnd1, Drer\ccnb1, Drer\ccnd3" "Scer\CLB6, Scer\CLB1, Scer\CLB3, Scer\CLN2, Scer\CLB5, Scer\CLN1, Scer\CLN3, Scer\CLB4, Scer\CLB2" Cele\cyd-1 "Xtro\ccnd2, Xtro\ccnd1, Xtro\ccndx" "Mmus\Ccnd3, Mmus\Ccnd2, Mmus\Ccnd1" "Hsap\CCND3, Hsap\CCND2, Hsap\CCNB1, Hsap\CCND1" " larval stage | third instar , embryonic stage | early , embryonic stage&&larval stage , adult stage | male , adult stage | female " " imaginal disc

, morphogenetic furrow | anterior

, eye-antennal disc

" "viable,sterile,recessive,small body,decreased cell number,increased cell size,somatic clone,size defective,wild-type,large body,increased cell number,decreased cell size" "wing,somatic clone,embryonic/larval midgut primordium" DRSC20233 IE -2.774952185 -3.585361354 -4.689582149 -2.175471354 -1.126952096 -0.50847421 FBgn0004237 Hrb87F Heterogeneous nuclear ribonucleoprotein at 87F http://flybase.org/reports/FBgn0004237 FBgn0010230 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity sequence-specific DNA binding ; GO:0043565 | inferred from direct assay "female gonad development ; GO:0008585 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with HGNC:2549" intracellular ribonucleoprotein complex ; GO:0030529 | inferred from sequence or structural similarity with HGNC:5031 inferred from direct assay inferred from physical interaction with sqd nucleoplasm ; GO:0005654 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay omega speckle ; GO:0035062 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 chromatin ; GO:0000785 | inferred from direct assay "hrp36, Hrb87f, CG12749, HRP36, P11, Q16, Q14, Hrp36, p38, P11/Hrb87F, Hrb87Fa, HRB87F/hrp36, Hrb85CD, Hrb2, Hrb87F, hnRNP36, hnRNPA1, HRB87F, hnRNP A2/B1, hnRNPA1/A2, hnRNPA2" IPR000504:RNA recognition motif domain CG12749 11-Aug-17 DroID_v2017_08 "Drer\msi2a, Drer\ncoa5, Drer\hnrnpa0b, Drer\raly, Drer\cirbpa, Drer\dazl, Drer\rbm34, Drer\hnrnpa1a, Drer\hnrnpa1b, Drer\hnrnpa0l, Drer\srsf10a, Drer\hnrpdl, Drer\hnrnpc, Drer\eif4ba, Drer\zcrb1, Drer\wu:fq32h04, Drer\hnrnpd, Drer\hnrnpa0a, Drer\trnau1apb, Drer\msi2b, Drer\trnau1apa, Drer\hnrnpa3, Drer\eif4h, Drer\rbm19, Drer\hnrnpabb, Drer\hnrnpaba, Drer\dazap1, Drer\zgc:55733" "Scer\HRP1, Scer\NGR1, Scer\CWC2, Scer\MUD1, Scer\NOP6, Scer\MRN1, Scer\NAB6, Scer\NAM8, Scer\NOP12" "Cele\H28G03.1, Cele\hrp-1, Cele\msi-1" "Xtro\trnau1ap, Xtro\rbm34, Xtro\ralyl, Xtro\msi1, Xtro\hnrnpa0, Xtro\hnrnpc, Xtro\hnrnpdl, Xtro\hnrnpab, Xtro\hnrnpa1, Xtro\dazap1, Xtro\eif4h, Xtro\raly, Xtro\hnrnpa2b1, Xtro\hnrnpd, Xtro\dazl, Xtro\hnrnpa3, Xtro\eif4b, Xtro\cirbp" "Mmus\Trnau1ap, Mmus\Gm21379, Mmus\Srsf10, Mmus\Hnrnpa0, Mmus\Dazap1, Mmus\Hnrnpdl, Mmus\Hnrnpab, Mmus\Eif4b, Mmus\Msi2, Mmus\Hnrnpd, Mmus\Rbm34, Mmus\Hnrnpa2b1, Mmus\Dazl, Mmus\Cirbp, Mmus\Hnrnpa3, Mmus\Tra2b, Mmus\Zcrb1, Mmus\Msi1, Mmus\Slirp, Mmus\Srsf12, Mmus\Hnrnpc, Mmus\Eif4h, Mmus\Rbm31y, Mmus\Boll, Mmus\Raly, Mmus\Hnrnpa1" "Hsap\MSI1, Hsap\HNRNPA1L2, Hsap\DAZAP1, Hsap\SRSF10, Hsap\BOLL, Hsap\HNRNPA2B1, Hsap\MSI2, Hsap\HNRNPAB, Hsap\DAZ4, Hsap\HNRNPDL, Hsap\SLIRP, Hsap\DAZ2, Hsap\RALY, Hsap\HNRNPA3, Hsap\DAZ3, Hsap\RALYL, Hsap\HNRNPA1, Hsap\DAZL, Hsap\EIF4H, Hsap\HNRNPA0, Hsap\RBM3, Hsap\HNRNPCL1, Hsap\HNRNPD, Hsap\CIRBP, Hsap\HNRNPC, Hsap\DAZ1, Hsap\TRNAU1AP, Hsap\RBM34, Hsap\EIF4B" " oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

"viable,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC16708 K -0.722385229 -0.234529108 0.041035676 -0.460785574 -2.914010715 -0.463847677 FBgn0003942 RpS27A Ribosomal protein S27A http://flybase.org/reports/FBgn0003942 "FBgn0002728, FBgn0010585, FBgn0064114" protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR002906 structural constituent of ribosome ; GO:0003735 | traceable author statement protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000003962 "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002906, InterPro:IPR011332 cytoplasmic translation ; GO:0002181 | traceable author statement protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000003962" ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR002906 microtubule associated complex ; GO:0005875 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "DUb80, l(2)04820, mfs48, UB3-D, mfs(2)48, mfs(2)31, l(2)31Ei, Ubi-m, Ubi-f80, Dub80, CG5271, RpS27A, Ubiq, RpS27" "IPR000626:Ubiquitin domain, IPR002906:Ribosomal protein S27a, IPR019954:Ubiquitin conserved site, IPR019956:Ubiquitin, IPR011332:Zinc-binding ribosomal protein, IPR029071:Ubiquitin-related domain" CG5271 11-Aug-17 DroID_v2017_08 "Drer\nedd8, Drer\uba52, Drer\ubb, Drer\rps27a, Drer\si:ch211-202a12.4, Drer\kxd1, Drer\nedd8l, Drer\ubc" Scer\RPS31 "Cele\ubl-1, Cele\ned-8, Cele\ubq-2, Cele\F52C6.2, Cele\F52C6.3, Cele\F34H10.1, Cele\kxd-1, Cele\K08C9.7" "Xtro\ubc, Xtro\kxd1, Xtro\uba52, Xtro\rps27a, Xtro\nedd8" "Mmus\Ubc, Mmus\Isg15, Mmus\Ubd, Mmus\Nedd8, Mmus\Ubb, Mmus\Rps27a" "Hsap\RPS27A, Hsap\UBB, Hsap\NEDD8, Hsap\ISG15, Hsap\UBC, Hsap\UBD, Hsap\UBA52" " larval stage | third instar , embryonic stage -- adult stage , adult stage " " embryonic/larval salivary gland

, embryonic/larval fat body

, ovary

, imaginal disc

, Malpighian tubule

" "lethal,recessive,female sterile,heat sensitive,male sterile,viable,reduced" "macrochaeta,spermatid" DRSC03421 IEK -2.04996412 -1.37594847 -2.306200434 -4.359150613 1.114867295 2.87032859 FBgn0027106 Inx7 Innexin 7 http://flybase.org/reports/FBgn0027106 - protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype intercellular transport ; GO:0010496 | inferred from sequence or structural similarity with Inx3 medium-term memory ; GO:0072375 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement gap junction ; GO:0005921 | inferred from direct assay "inx-7, D-inx-7, Dm-inx7, prp7, CG32731, CG2977, inx7, FBpp0070994, Inx7" IPR000990:Innexin CG2977 11-Aug-17 DroID_v2017_08 "Drer\panx3, Drer\panx1b" - "Cele\inx-6, Cele\inx-15, Cele\inx-16, Cele\inx-2, Cele\inx-20, Cele\inx-9, Cele\inx-5, Cele\inx-14, Cele\inx-17, Cele\inx-8, Cele\inx-13, Cele\inx-19, Cele\inx-22, Cele\eat-5, Cele\inx-11, Cele\unc-7, Cele\inx-12, Cele\unc-9, Cele\inx-1, Cele\che-7, Cele\inx-21, Cele\inx-18, Cele\inx-7, Cele\inx-10, Cele\inx-3" - - - "neuroanatomy defective,memory defective,heat sensitive,viable,fertile" "presumptive embryonic/larval central nervous system,ventral nerve cord | embryonic stage,presumptive embryonic/larval peripheral nervous system,anterior commissure | embryonic stage,posterior commissure | embryonic stage,longitudinal connective | embryonic stage" FBgn0014857 His3.3A Histone H3.3A http://flybase.org/reports/FBgn0014857 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000164, InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072" cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from genetic interaction with His3.3B nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR000164 polytene chromosome ; GO:0005700 | inferred from direct assay "H3.3, His3.3, PH3, CG5825, His3.3A, dH3.3A, H3.3A, His-3.3A" "IPR000164:Histone H3/CENP-A, IPR007125:Histone H2A/H2B/H3, IPR009072:Histone-fold" CG5825 11-Aug-17 DroID_v2017_08 "Drer\h3f3c, Drer\si:ch1073-429i10.3, Drer\zgc:173552, Drer\h3f3a, Drer\zgc:113984, Drer\h3f3b.1, Drer\LOC108190747, Drer\hist2h3c, Drer\h3f3d, Drer\zgc:113983, Drer\si:dkey-23a13.8, Drer\si:ch73-36p18.2, Drer\hist2h3ca1, Drer\cenpa, Drer\LOC108190746" "Scer\HHT2, Scer\HHT1, Scer\CSE4" "Cele\his-13, Cele\his-72, Cele\his-45, Cele\his-49, Cele\his-70, Cele\his-6, Cele\his-55, Cele\his-71, Cele\his-63, Cele\his-42, Cele\his-59, Cele\his-2, Cele\his-32, Cele\his-69, Cele\his-27, Cele\his-9, Cele\his-25, Cele\his-17, Cele\his-74" "Xtro\hist2h3d, Xtro\h3f3a, Xtro\h3f3b, Xtro\cenpa, Xtro\h3f3b" "Mmus\Hist1h3i, Mmus\Hist1h3g, Mmus\Hist1h3d, Mmus\Hist1h3h, Mmus\Hist1h3a, Mmus\H3f3b, Mmus\Hist1h3b, Mmus\Hist1h3f, Mmus\H3f3a, Mmus\Hist2h2be, Mmus\Hist2h3c1, Mmus\Cenpa, Mmus\Hist2h3b, Mmus\Hist1h3e, Mmus\Hist2h3c2, Mmus\Hist1h3c" "Hsap\H3F3B, Hsap\HIST1H3I, Hsap\HIST1H3G, Hsap\HIST1H3H, Hsap\HIST1H3E, Hsap\H3F3C, Hsap\HIST1H3C, Hsap\HIST2H3C, Hsap\HIST3H3, Hsap\HIST1H3A, Hsap\HIST1H3J, Hsap\HIST1H3B, Hsap\HIST2H3D, Hsap\CENPA, Hsap\HIST2H3A, Hsap\H3F3A, Hsap\HIST1H3F, Hsap\HIST1H3D" spermatogenesis && adult stage testis

" spermatogenesis && adult stage , larval stage " " protein body

, spermatocyte

, Y chromosome loop

, larval salivary gland

, spermatid

" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC03343 IEK -1.300171076 -4.616387217 -1.703889291 -2.626317686 0.327610113 1.778029732 FBgn0032664 CG5755 - http://flybase.org/reports/FBgn0032664 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.163, CG5755" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG5755 11-Aug-17 DroID_v2017_08 Drer\slc25a46 - Cele\slc-25A46 "Xtro\slc25a46, Xtro\slc25a19" Mmus\Slc25a46 Hsap\SLC25A46 "partially lethal - majority die,some die during pupal stage" FBgn0024963 GluClalpha GluClalpha http://flybase.org/reports/FBgn0024963 FBgn0063176 protein_coding_gene extracellular-glutamate-gated chloride channel activity ; GO:0008068 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201 plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred by curator from GO:0008068" "DrosGluCl-alpha1, dGluCl-alpha, CG7535, GluCla, DmGlu, DrosGlu-Cl-alpha, DmGluClalpha, GluCl, glc, DrosGluCl-alpha, DrosGluCl, GLUCL, GluClalpha, BcDNA:HL07853, Dm-GluCl, CT23049, glu" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR015680:Glutamate-Gated Chloride Channel" CG7535 11-Aug-17 DroID_v2017_08 "Drer\gabrr2b, Drer\zgc:110204, Drer\gabrp, Drer\gabrz, Drer\LOC562831, Drer\glrbb, Drer\LOC100330554, Drer\glra1, Drer\glrba, Drer\gabrb1, Drer\gabra1, Drer\gabra5, Drer\gabrr1, Drer\glra4b, Drer\gabrb4, Drer\glra4a, Drer\gabrb3, Drer\glra3, Drer\gabrr2a, Drer\LOC561083, Drer\gabrd, Drer\si:dkey-52k1.6, Drer\si:dkey-155h10.3, Drer\gabrb2, Drer\gabra6a, Drer\LOC100001259, Drer\gabrg2, Drer\glra2, Drer\gabra6b, Drer\gabrr3a" - "Cele\lgc-37, Cele\avr-14, Cele\lgc-41, Cele\lgc-44, Cele\ggr-1, Cele\lgc-39, Cele\gab-1, Cele\glc-3, Cele\unc-49, Cele\lgc-40, Cele\avr-15, Cele\lgc-38, Cele\glc-2, Cele\lgc-36, Cele\glc-1, Cele\lgc-42, Cele\glc-4" "Xtro\gabra6, Xtro\glra2, Xtro\glra3, Xtro\gabrg2, Xtro\glrb, Xtro\gabra5, Xtro\gabrb3, Xtro\gabra2, Xtro\gabrr3, Xtro\gabrd, Xtro\gabrp, Xtro\glra1, Xtro\LOC100490720" "Mmus\Gabra1, Mmus\Gabre, Mmus\Gabrb3, Mmus\Gabrb2, Mmus\Gabra3, Mmus\Gabrd, Mmus\Glra2, Mmus\Gabrg3, Mmus\Glra3, Mmus\Gabrr1, Mmus\Gabrp, Mmus\Gabrq, Mmus\Gabrg2, Mmus\Gabra6, Mmus\Gabra5, Mmus\Gabrr2, Mmus\Gabrr3, Mmus\Gabrg1, Mmus\Glrb, Mmus\Glra1, Mmus\Glra4, Mmus\Gabra2, Mmus\Gabrb1" "Hsap\GABRG3, Hsap\GABRQ, Hsap\GABRA5, Hsap\GABRR2, Hsap\GABRR1, Hsap\GABRD, Hsap\GLRA4, Hsap\GABRE, Hsap\GABRP, Hsap\GABRA6, Hsap\GABRA2, Hsap\GLRA3, Hsap\GABRG1, Hsap\GABRA4, Hsap\GABRB1, Hsap\GABRR3, Hsap\GABRG2, Hsap\GLRA1, Hsap\GLRA2, Hsap\GLRB, Hsap\GABRB3, Hsap\GABRB2, Hsap\GABRA1" " embryonic stage , adult stage , larval stage " viable FBgn0013675 mt:CoII mitochondrial Cytochrome c oxidase subunit II http://flybase.org/reports/FBgn0013675 FBgn0002867 protein_coding_gene "copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR001505, InterPro:IPR002429 cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000527128" ATP synthesis coupled electron transport ; GO:0042773 | inferred from biological aspect of ancestor with PANTHER:PTN000527128 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011759, InterPro:IPR014222 mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000527130" "CG34069, COX, CO II, II, COII, CO, COXII, mt:CoII, Cox2, CO2, mt COII, cox2, CoII, mt-CO2, CcO subunit II, MT-CO2, COX2, mt:Cox2, Co-II" "IPR001505:Copper centre Cu(A), IPR002429:Cytochrome c oxidase subunit II-like C-terminal, IPR008972:Cupredoxin, IPR011759:Cytochrome C oxidase subunit II, transmembrane domain, IPR014222:Cytochrome c oxidase, subunit II, IPR034210:Cytochrome c oxidase subunit 2, C-terminal" CG34069 11-Aug-17 DroID_v2017_08 Drer\COX2 Scer\COX2 Cele\COX2 Xtro\COX2 Mmus\COX2 Hsap\COX2 FBgn0011837 Tis11 Tis11 zinc finger protein http://flybase.org/reports/FBgn0011837 "FBgn0063277, FBgn0027302" protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay mRNA 3'-UTR AU-rich region binding ; GO:0035925 | inferred from direct assay "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:1900153 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from direct assay 3'-UTR-mediated mRNA destabilization ; GO:0061158 | inferred from direct assay RNA interference ; GO:0016246 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P47973 "dTTP, dTis11, TIScc1, DTIS11, clone 1.28, TIS11cc1, l(1)G0124, anon-EST:Liang-1.28, CG4070, Tis11, TIS11, tis-11, Ts11, dTIS11" "IPR000571:Zinc finger, CCCH-type" CG4070 11-Aug-17 DroID_v2017_08 "Drer\zgc:162730, Drer\cth1, Drer\zfp36l1b, Drer\zfp36l2, Drer\zgc:114130, Drer\LOC100334443, Drer\zfp36l1a" "Scer\CTH1, Scer\TIS11" "Cele\mex-1, Cele\ccch-2, Cele\gla-3, Cele\mex-6, Cele\dct-13, Cele\moe-3, Cele\ccch-5, Cele\pie-1, Cele\oma-2, Cele\ccch-1, Cele\Y116A8C.20, Cele\oma-1, Cele\mex-5, Cele\Y116A8C.19, Cele\C35D6.4, Cele\Y60A9.3, Cele\pos-1, Cele\F38C2.7" "Xtro\zfp36l2, Xtro\zfp36l1, Xtro\zfp36, Xtro\zfp36l2.1, Xtro\zfp36l2.2" "Mmus\Zfp36l1, Mmus\Zfp36l3, Mmus\Zfp36l2, Mmus\Zfp36" "Hsap\ZFP36L2, Hsap\ZFP36, Hsap\ZFP36L1" " embryonic stage | early , embryonic stage | >3hr " "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible" "eye,retinal pigment cell,rhabdomerelz-gal4" FBgn0030096 Zpr1 Zpr1 http://flybase.org/reports/FBgn0030096 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004457 translation initiation factor binding ; GO:0031369 | inferred from sequence or structural similarity with UniProtKB:O75312 "cellular response to epidermal growth factor stimulus ; GO:0071364 | inferred from sequence or structural similarity with UniProtKB:O75312 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype pre-mRNA catabolic process ; GO:1990261 | inferred from sequence or structural similarity with UniProtKB:O75312 lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:O75312 SMN complex ; GO:0032797 | inferred from sequence or structural similarity with UniProtKB:O75312 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000093465 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000093466 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:O75312 "CG9060, Zpr1" "IPR004457:Zinc finger, ZPR1-type" CG9060 11-Aug-17 DroID_v2017_08 Drer\zpr1 Scer\ZPR1 Cele\W03F9.1 Xtro\zpr1 Mmus\Zpr1 Hsap\ZPR1 "viable,visible" "embryonic/larval trachea,somatic clone,tracheal lumen,trichogen cell" FBgn0010747 Srp54k Signal recognition particle protein 54k http://flybase.org/reports/FBgn0010747 FBgn0027916 protein_coding_gene "7S RNA binding ; GO:0008312 | inferred from electronic annotation with InterPro:IPR004125, InterPro:IPR006325 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000897, InterPro:IPR006325, InterPro:IPR013822, InterPro:IPR022941 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR006325, InterPro:IPR022941 signal sequence binding ; GO:0005048 | inferred from sequence or structural similarity" "SRP-dependent cotranslational protein targeting to membrane ; GO:0006614 | inferred from electronic annotation with InterPro:IPR000897, InterPro:IPR004125, InterPro:IPR006325, InterPro:IPR013822, InterPro:IPR022941 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition ; GO:0006617 | inferred from sequence or structural similarity" "signal recognition particle ; GO:0048500 | inferred from electronic annotation with InterPro:IPR004125, InterPro:IPR006325, InterPro:IPR022941 signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from sequence or structural similarity" "CG4659, Srp54, l(3)01418, BcDNA.GM09489, BcDNA:GM09489, Srp54k" "IPR000897:Signal recognition particle, SRP54 subunit, GTPase domain, IPR003593:AAA+ ATPase domain, IPR004125:Signal recognition particle, SRP54 subunit, M-domain, IPR006325:Signal recognition particle, SRP54 subunit, eukaryotic, IPR013822:Signal recognition particle, SRP54 subunit, helical bundle, IPR032675:Leucine-rich repeat domain, L domain-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022941:Signal recognition particle, SRP54 subunit" CG4659 11-Aug-17 DroID_v2017_08 Drer\srp54 Scer\SRP54 Cele\F21D5.7 Xtro\srp54 "Mmus\Srp54b, Mmus\Srp54c, Mmus\Srp54a" Hsap\SRP54 "lethal,recessive" "lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous" FBgn0030669 CG9240 - http://flybase.org/reports/FBgn0030669 protein_coding_gene "serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR000223, InterPro:IPR019758" mitochondrial respiratory chain complex assembly ; GO:0033108 | inferred from biological aspect of ancestor with PANTHER:PTN000272697 protein processing involved in protein targeting to mitochondrion ; GO:0006627 | inferred from biological aspect of ancestor with PANTHER:PTN000272697 signal peptide processing ; GO:0006465 | inferred from biological aspect of ancestor with PANTHER:PTN000272698 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR019758 mitochondrial inner membrane peptidase complex ; GO:0042720 | inferred from biological aspect of ancestor with PANTHER:PTN000272697 "anon-EST:Posey267, CG9240" "IPR000223:Peptidase S26A, signal peptidase I, IPR015927:Peptidase S24/S26A/S26B/S26C, IPR019758:Peptidase S26A, signal peptidase I, conserved site, IPR026730:Mitochondrial inner membrane protease subunit 1, IPR019533:Peptidase S26" CG9240 11-Aug-17 DroID_v2017_08 Drer\immp1l Scer\IMP1 Cele\immp-1 Xtro\immp1l Mmus\Immp1l Hsap\IMMP1L viable FBgn0035767 CG8596 - http://flybase.org/reports/FBgn0035767 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "CG8596, cln7" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8596 11-Aug-17 DroID_v2017_08 "Drer\mfsd8, Drer\LOC564731" - "Cele\C25E10.4, Cele\W01B6.3, Cele\W03C9.6, Cele\C25E10.5, Cele\T28C12.2, Cele\W05E10.1, Cele\T28C12.1, Cele\F58G11.4, Cele\F57A8.7, Cele\Y53G8AR.7, Cele\ZK550.2, Cele\F52F10.2, Cele\F14D7.6, Cele\F27D9.2, Cele\srsx-34" Xtro\mfsd8 Mmus\Mfsd8 Hsap\MFSD8 viable FBgn0035785 ppk26 pickpocket 26 http://flybase.org/reports/FBgn0035785 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 larval turning behavior ; GO:0035179 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception of pain ; GO:0050966 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception of pain ; GO:0050966 | inferred from expression pattern sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 dendrite membrane ; GO:0032590 | inferred from direct assay "CG8546, ppk26, bba" "IPR020903:Epithelial sodium channel, conserved site, IPR001873:Epithelial sodium channel" CG8546 11-Aug-17 DroID_v2017_08 "Drer\asic1b, Drer\asic2, Drer\asic1c, Drer\asic1a, Drer\asic4b, Drer\asic4a" - "Cele\delm-2, Cele\deg-1, Cele\acd-3, Cele\delm-1, Cele\del-9, Cele\mec-4, Cele\del-6, Cele\flr-1, Cele\del-8, Cele\asic-2, Cele\del-4, Cele\del-7, Cele\mec-10" "Xtro\scnn1g, Xtro\asic4, Xtro\asic1, Xtro\scnn1b, Xtro\asic5, Xtro\scnn1a, Xtro\scnn1d" "Mmus\Asic5, Mmus\Asic4, Mmus\Asic2, Mmus\Scnn1b, Mmus\Asic1, Mmus\Scnn1g, Mmus\Asic3, Mmus\Scnn1a" "Hsap\ASIC5, Hsap\ASIC2, Hsap\ASIC3, Hsap\SCNN1D, Hsap\SCNN1A, Hsap\SCNN1G, Hsap\SCNN1B, Hsap\ASIC1, Hsap\ASIC4" "partially lethal - majority die,some die during pupal stage,viable" FBgn0032987 RpL21 Ribosomal protein L21 http://flybase.org/reports/FBgn0032987 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001147, InterPro:IPR018259 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" ribosome ; GO:0005840 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "CG12775, anon-EST:Posey30, anon-EST:Posey18, BcDNA:RH06526, RpL21, RPL21, Rp L21" "IPR018259:Ribosomal protein L21e, conserved site, IPR001147:Ribosomal protein L21e, IPR008991:Translation protein SH3-like domain" CG12775 11-Aug-17 DroID_v2017_08 Drer\rpl21 "Scer\RPL21A, Scer\RPL21B" Cele\rpl-21 Xtro\rpl21 Mmus\Rpl21 Hsap\RPL21 lethal DRSC03704 EK -0.058292519 -0.888829945 0.875920913 -5.127087486 0.870875276 3.196471541 FBgn0031855 CG11221 - http://flybase.org/reports/FBgn0031855 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000684417 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000684417 protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000684417 cellular_component ; GO:0005575 | no biological data available "PKN, CG11221, Pkn" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG11221 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-183d21.3, Drer\LOC791840, Drer\unm_sa1261, Drer\sbk3, Drer\si:ch211-171h4.3, Drer\si:dkey-8e10.3, Drer\bsk146" Scer\CHK1 "Cele\ikke-1, Cele\Y39G8B.5, Cele\C01C4.3" "Xtro\LOC100496267, Xtro\LOC100135243, Xtro\sbk1, Xtro\sbk2, Xtro\LOC100495913" "Mmus\Sbk3, Mmus\Sbk2, Mmus\Sbk1" "Hsap\SBK1, Hsap\SBK2, Hsap\SBK3" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0036764 CG5535 - http://flybase.org/reports/FBgn0036764 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002293 "anon-WO0118547.111, CG5535" "IPR002293:Amino acid/polyamine transporter I, IPR029485:Cationic amino acid transporter, C-terminal" CG5535 11-Aug-17 DroID_v2017_08 "Drer\slc7a4, Drer\slc7a1, Drer\slc7a14a, Drer\slc7a3a, Drer\zgc:175280, Drer\slc7a2, Drer\slc7a14b, Drer\slc7a3b, Drer\zgc:63694" "Scer\PUT4, Scer\TAT1, Scer\BAP3, Scer\AGP1, Scer\GAP1, Scer\UGA4, Scer\SAM3, Scer\CAN1, Scer\ALP1, Scer\TAT2, Scer\AGP2, Scer\LYP1, Scer\GNP1, Scer\MMP1, Scer\AGP3, Scer\DIP5, Scer\SSY1, Scer\HIP1, Scer\BAP2" "Cele\Y53F4B.12, Cele\aat-5, Cele\C50D2.2, Cele\F23F1.6, Cele\B0454.6" "Xtro\slc7a14, Xtro\slc7a3, Xtro\slc7a2.2, Xtro\slc7a2.1, Xtro\slc7a4, Xtro\slc7a1" "Mmus\Slc7a14, Mmus\Slc7a2, Mmus\AU018091, Mmus\Slc7a3, Mmus\Slc7a4, Mmus\Slc7a1" "Hsap\SLC7A1, Hsap\SLC7A3, Hsap\SLC7A4, Hsap\SLC7A14, Hsap\SLC7A2" "viable,visible" trichogen cell FBgn0034025 GalNAc-T1 GalNAc-T1 http://flybase.org/reports/FBgn0034025 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement "pgant1, CG8182, GalNAc-T1" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG8182 11-Aug-17 DroID_v2017_08 "Drer\poc1bl, Drer\galnt6, Drer\LOC100334784, Drer\LOC100535692, Drer\galnt8a.1, Drer\galnt2, Drer\galnt8b, Drer\galnt7, Drer\galnt13, Drer\galnt16, Drer\galnt10, Drer\galnt11, Drer\galnt12, Drer\galnt18a, Drer\galnt9, Drer\si:ch211-15e22.3, Drer\galnt8a.2, Drer\LOC101882942, Drer\galnt1, Drer\galnt14, Drer\galnt18b, Drer\galnt3, Drer\LOC568645, Drer\LOC103910015, Drer\wbscr17, Drer\LOC101886587" - "Cele\gly-10, Cele\gly-11, Cele\gly-7, Cele\gly-5, Cele\gly-3, Cele\gly-6, Cele\gly-9" "Xtro\galnt2, Xtro\galnt14, Xtro\galnt1, Xtro\galnt6.1, Xtro\galnt13, Xtro\galnt7, Xtro\galnt4, Xtro\galnt10, Xtro\wbscr17, Xtro\galnt15, Xtro\galnt16, Xtro\galnt12, Xtro\galnt9" "Mmus\Galnt15, Mmus\Galnt11, Mmus\Galnt18, Mmus\Galnt3, Mmus\Galntl6, Mmus\Galnt6, Mmus\Galnt4, Mmus\Galnt5, Mmus\Galnt13, Mmus\Galnt1, Mmus\Galnt7, Mmus\Galnt10, Mmus\Galnt12, Mmus\Galnt9, Mmus\Galnt16, Mmus\Galnt14, Mmus\Galnt2, Mmus\Galntl5, Mmus\Wbscr17" "Hsap\GALNT1, Hsap\WBSCR17, Hsap\GALNTL5, Hsap\GALNT3, Hsap\GALNT18, Hsap\GALNT8, Hsap\GALNT6, Hsap\GALNT4, Hsap\GALNTL6, Hsap\GALNT9, Hsap\GALNT15, Hsap\GALNT5, Hsap\GALNT7, Hsap\GALNT12, Hsap\GALNT13, Hsap\GALNT14, Hsap\GALNT11, Hsap\POC1B-GALNT4, Hsap\GALNT10, Hsap\GALNT16, Hsap\GALNT2" "viable,fertile" FBgn0030345 CG1847 - http://flybase.org/reports/FBgn0030345 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG1847 "IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG1847 11-Aug-17 DroID_v2017_08 "Drer\tomm34, Drer\LOC100534741, Drer\aip, Drer\tomm70a, Drer\aipl1" "Scer\TOM71, Scer\TOM70" Cele\C56C10.10 "Xtro\aipl1, Xtro\aip, Xtro\spag1, Xtro\tomm70a" "Mmus\Aipl1, Mmus\Spag1, Mmus\Aip, Mmus\Tomm34, Mmus\Tomm70a" "Hsap\TOMM70, Hsap\SPAG1, Hsap\AIPL1, Hsap\TOMM34, Hsap\AIP" viable FBgn0035436 CG12016 - http://flybase.org/reports/FBgn0035436 protein_coding_gene ribosylnicotinamide kinase activity ; GO:0050262 | inferred from sequence or structural similarity with SGD:S000005073 nicotinamide nucleotide biosynthetic process ; GO:0019359 | inferred from electronic annotation with InterPro:IPR026681 nicotinamide riboside metabolic process ; GO:0046495 | inferred from sequence or structural similarity with SGD:S000005073 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005073 "CG12016, Dromel_CG12016_FBtr0073063_mORF" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026681:Nicotinamide riboside kinase" CG12016 11-Aug-17 DroID_v2017_08 "Drer\mibp2, Drer\LOC103911725, Drer\nmrk2, Drer\nmrk1, Drer\mibp" Scer\NRK1 Cele\T27A3.6 "Xtro\nmrk2, Xtro\nmrk1" "Mmus\Nmrk1, Mmus\Nmrk2, Mmus\Mocs2" "Hsap\NMRK1, Hsap\NMRK2, Hsap\MOCS2" viable DRSC08224 K -1.100866548 -0.127186471 -0.161024089 -1.440469696 1.356219706 2.321001171 FBgn0052320 CG32320 - http://flybase.org/reports/FBgn0052320 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012858 CG32320 IPR012858:Dendritic cell-specific transmembrane protein-like CG32320 11-Aug-17 DroID_v2017_08 "Drer\dcst1, Drer\dcst2" - "Cele\srh-97, Cele\spe-42, Cele\K12B6.2" "Xtro\LOC101734522, Xtro\LOC100497585" "Mmus\Dcst1, Mmus\Dcst2, Mmus\Dcstamp" "Hsap\DCST2, Hsap\DCSTAMP, Hsap\DCST1" FBgn0037902 CG5281 - http://flybase.org/reports/FBgn0037902 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000620 CG5281 IPR000620:EamA domain CG5281 11-Aug-17 DroID_v2017_08 "Drer\slc35g2b, Drer\si:ch211-197g18.2, Drer\slc35g2a" "Scer\YMR253C, Scer\YPL264C" - Xtro\slc35g1 "Mmus\Slc35g3, Mmus\Slc35g1, Mmus\Slc35g2" "Hsap\SLC35G4, Hsap\SLC35G1, Hsap\SLC35G3, Hsap\SLC35G6, Hsap\SLC35G5, Hsap\SLC35G2" viable FBgn0004854 B-H2 BarH2 http://flybase.org/reports/FBgn0004854 - protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from mutant phenotype transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001228 | inferred from biological aspect of ancestor with PANTHER:PTN001551673 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001551673" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001551673 nucleus ; GO:0005634 | inferred by curator from GO:0003705 "BarH, BH2, Bar, B, Bar-H2, CG5488, B-H2, BarH2, bar-h2, Barh2" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR020479:Homeobox domain, metazoa" CG5488 11-Aug-17 DroID_v2017_08 "Drer\lbx2, Drer\tlx1, Drer\barhl1a, Drer\lbx1b, Drer\tlx3b, Drer\barhl1b, Drer\lbx1a, Drer\dbx1b, Drer\ved, Drer\hlx1, Drer\barx1, Drer\tlx2, Drer\barx2, Drer\pnx, Drer\LOC100008066, Drer\nkx1.2lb, Drer\vox, Drer\barhl2" - "Cele\ceh-30, Cele\ceh-31" "Xtro\tlx1, Xtro\dbx1, Xtro\hlx, Xtro\ventx1.2, Xtro\nkx1-2, Xtro\nkx1-1, Xtro\barhl1, Xtro\barhl2, Xtro\tlx3, Xtro\barx1, Xtro\tlx2" "Mmus\Lbx1, Mmus\Barx1, Mmus\Dbx2, Mmus\Lbx2, Mmus\Tlx2, Mmus\Arx, Mmus\Dbx1, Mmus\Barx2, Mmus\Barhl2, Mmus\Barhl1, Mmus\Nkx1-2, Mmus\Tlx1, Mmus\Tlx3, Mmus\Hlx, Mmus\Nkx1-1" "Hsap\TLX2, Hsap\TLX1, Hsap\BARX2, Hsap\NKX1-1, Hsap\BARHL2, Hsap\DBX2, Hsap\TLX3, Hsap\LBX2, Hsap\HLX, Hsap\BARHL1, Hsap\BARX1, Hsap\LBX1, Hsap\DBX1" embryonic stage " neuron

, embryonic central nervous system

, peripheral nervous system

, external sensory organ

, thecogen cell

" " pupal stage | >20 hr , embryonic stage , larval stage | late -- P | early " " primary pigment cell

, neuron

, thecogen cell

, embryonic central nervous system

, photoreceptor cell R6 | presumptive

, external sensory organ

, peripheral nervous system

" "visible,recessive,body color defective,partially lethal - majority die,some die during pupal stage" "scutellum,wing,adult head,scutellum & microchaeta,wing & microchaeta,microchaeta & head capsule & adult,microchaeta,ectopic,prescutum & macrochaeta,tarsal segment 3,tarsal segment 4,pretarsus,ventral thoracic disc,morphogenetic furrow,photoreceptor cell,leg,eye,chaeta,supernumerary,mesothoracic tergum" FBgn0051712 CG31712 - http://flybase.org/reports/FBgn0051712 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31712, CG5879" IPR033371:Arginine and glutamate-rich protein 1 CG31712 11-Aug-17 DroID_v2017_08 "Drer\arglu1a, Drer\arglu1b" - Cele\F44E2.3 Xtro\arglu1 Mmus\Arglu1 Hsap\ARGLU1 viable FBgn0029006 Smurf SMAD specific E3 ubiquitin protein ligase http://flybase.org/reports/FBgn0029006 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P42003 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with UniProtKB:Q9HAU4 embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from genetic interaction with fu inferred from genetic interaction with tkv negative regulation of gene expression ; GO:0010629 | inferred from direct assay negative regulation of BMP signaling pathway ; GO:0030514 | inferred from genetic interaction with fu inferred from genetic interaction with tkv regulation of growth ; GO:0040008 | inferred from mutant phenotype inferred from genetic interaction with RpL36 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype embryonic hindgut morphogenesis ; GO:0048619 | inferred from mutant phenotype decapentaplegic signaling pathway ; GO:0008101 | inferred from mutant phenotype ubiquitin ligase complex ; GO:0000151 | inferred from sequence or structural similarity with UniProtKB:Q9HAU4 cytoplasm ; GO:0005737 | inferred from physical interaction with wts "Smurf ubiquitin ligase, dSmurf, D-smurf, Dsmurf, Smurf, DSmurf, dSmurf1, CG4943, SMURF, LACK, d-smurf, lack, Lack, smurf" "IPR000008:C2 domain, IPR000569:HECT domain, IPR001202:WW domain" CG4943 11-Aug-17 DroID_v2017_08 "Drer\LOC100334952, Drer\yap1, Drer\hecw1b, Drer\hecw2a, Drer\itcha, Drer\wwtr1, Drer\nedd4a, Drer\smurf1, Drer\bag3, Drer\smurf2, Drer\wwp2, Drer\hecw2b, Drer\nedd4l" "Scer\TOM1, Scer\RSP5" "Cele\Y92H12A.2, Cele\wwp-1" "Xtro\itch, Xtro\nedd4l, Xtro\nedd4, Xtro\smurf1, Xtro\bag3, Xtro\hecw1, Xtro\wwp2" "Mmus\Yap1, Mmus\Wwp1, Mmus\Wwp2, Mmus\Nedd4, Mmus\Itch, Mmus\Hecw1, Mmus\Nedd4l, Mmus\Hecw2, Mmus\Smurf1, Mmus\Gas7, Mmus\Smurf2, Mmus\Bag3" "Hsap\HECW1, Hsap\GAS7, Hsap\NEDD4L, Hsap\NEDD4, Hsap\SMURF1, Hsap\WWP2, Hsap\ITCH, Hsap\BAG3, Hsap\WWP1, Hsap\SMURF2, Hsap\HECW2, Hsap\YAP1" "viable,fertile,lethal,rescuable maternal effect,lethal - all die before end of P-stage,some die during pharate adult stage,partially,visible,recessive,somatic clone,body color defective" "embryonic/first instar larval cuticle,rescuable maternal effect,embryonic head,amnioserosa,embryonic hindgut,stomodeum,dorsal,wing,leg,eye,somatic clone,mesothoracic tergum" DRSC07641 E 0.777610595 0.837193219 1.677739866 -1.155367533 0.183854375 0.006576088 FBgn0029935 CG4615 - http://flybase.org/reports/FBgn0029935 protein_coding_gene - cytolysis ; GO:0019835 | inferred from electronic annotation with InterPro:IPR005744 phagocytosis ; GO:0006909 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004254, InterPro:IPR005744" CG4615 "IPR004254:AdipoR/Haemolysin-III-related, IPR005744:Hly-III" CG4615 11-Aug-17 DroID_v2017_08 "Drer\mmd2a, Drer\LOC103909971, Drer\mmd" - Cele\Y71G12B.23 Xtro\mmd "Mmus\Mmd2, Mmus\Mmd" "Hsap\MMD, Hsap\MMD2" "lethal,neuroanatomy defective,viable" "embryonic/larval neuroblast,ganglion mother cell" DRSC26722 K 0.156996644 -0.265364741 0.28377132 -0.231610732 -1.023384634 -1.612059664 FBgn0024365 CG12773 - http://flybase.org/reports/FBgn0024365 - protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR004841 "EG:8D8.3, CG12773" IPR004841:Amino acid permease/ SLC12A domain CG12773 11-Aug-17 DroID_v2017_08 "Drer\slc12a8, Drer\slc12a1, Drer\slc12a10.3, Drer\slc12a10.2, Drer\slc12a3, Drer\slc12a10.1" Scer\VHC1 "Cele\F10E7.9, Cele\B0303.11, Cele\nkcc-1" "Xtro\slc12a3, Xtro\slc12a8, Xtro\slc12a1" "Mmus\Slc12a2, Mmus\Slc12a3, Mmus\Slc12a1, Mmus\Slc12a8" "Hsap\SLC12A3, Hsap\ZNF148, Hsap\SLC12A2, Hsap\SLC12A8, Hsap\SLC12A1" viable FBgn0264000 GluRIB Glutamate receptor IB http://flybase.org/reports/FBgn0264000 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from sequence or structural similarity with GluRIA AMPA glutamate receptor activity ; GO:0004971 | inferred from biological aspect of ancestor with PANTHER:PTN000438080 cation transport ; GO:0006812 | inferred from sequence or structural similarity with GluRIA AMPA glutamate receptor complex ; GO:0032281 | inferred from biological aspect of ancestor with PANTHER:PTN000438080 ionotropic glutamate receptor complex ; GO:0008328 | inferred from sequence or structural similarity with GluRIA "CG43743, GluRIB, Glu-R1B, CG4481, dglur-IB, DGluR-IB, GluRIb, CG42509, DmelGlu-R1B, Glu-RIB, Dm_3L:43677" "IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, IPR001320:Ionotropic glutamate receptor, IPR001828:Receptor, ligand binding region" CG43743 11-Aug-17 DroID_v2017_08 "Drer\gria4a, Drer\gria1b, Drer\gria3b, Drer\gria3a, Drer\LOC100334689, Drer\gria1a, Drer\gria2a, Drer\gria4b, Drer\grik1b, Drer\gria2b, Drer\grik2, Drer\grik1a" - "Cele\glr-1, Cele\glr-2" "Xtro\gria3, Xtro\grik1, Xtro\gria4, Xtro\gria1" "Mmus\Grik2, Mmus\Gria2, Mmus\Gria4, Mmus\Gria1, Mmus\Gria3, Mmus\Grik1, Mmus\Grik3" "Hsap\GRIK2, Hsap\GRIK3, Hsap\GRIA3, Hsap\GRIA1, Hsap\GRIK1, Hsap\GRIA2, Hsap\GRIA4" FBgn0036703 CG7707 - http://flybase.org/reports/FBgn0036703 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG7707, FBXO8" - CG7707 11-Aug-17 DroID_v2017_08 - - Cele\T10E9.1 - - - viable FBgn0028434 Ercc1 Ercc1 http://flybase.org/reports/FBgn0028434 protein_coding_gene single-stranded DNA endodeoxyribonuclease activity ; GO:0000014 | inferred from biological aspect of ancestor with PANTHER:PTN000297520 damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000297520 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000297520 protein binding ; GO:0005515 | inferred from physical interaction with mei-9 single-stranded DNA endodeoxyribonuclease activity ; GO:0000014 | contributes_to inferred from sequence or structural similarity with SGD:S000005943 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with mei-9 protein binding ; GO:0005515 | inferred from physical interaction with hdm "meiotic mismatch repair ; GO:0000710 | inferred from biological aspect of ancestor with PANTHER:PTN000297520 UV-damage excision repair ; GO:0070914 | inferred from biological aspect of ancestor with PANTHER:PTN000297520 resolution of meiotic recombination intermediates ; GO:0000712 | inferred from mutant phenotype mitotic recombination ; GO:0006312 | inferred from biological aspect of ancestor with PANTHER:PTN000297520 nucleotide-excision repair, DNA incision, 5'-to lesion ; GO:0006296 | inferred from sequence or structural similarity with SGD:S000005943 reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype nucleotide-excision repair, DNA incision, 5'-to lesion ; GO:0006296 | inferred from biological aspect of ancestor with PANTHER:PTN000297520 nucleotide-excision repair ; GO:0006289 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype" ERCC4-ERCC1 complex ; GO:0070522 | inferred from biological aspect of ancestor with PANTHER:PTN000297520 protein complex ; GO:0043234 | inferred from direct assay nucleotide-excision repair factor 1 complex ; GO:0000110 | inferred from biological aspect of ancestor with PANTHER:PTN000297520 "ERCC1, CG10215, Ercc1" "IPR004579:ERCC1/RAD10/SWI10 family, IPR010994:RuvA domain 2-like, IPR011335:Restriction endonuclease type II-like" CG10215 11-Aug-17 DroID_v2017_08 "Drer\ercc1, Drer\faap24" Scer\RAD10 Cele\ercc-1 "Xtro\faap24, Xtro\ercc1" "Mmus\Ercc1, Mmus\Faap24" "Hsap\FAAP24, Hsap\ERCC1" "radiation sensitive,chemical sensitive,viable" DRSC07424 IE -1.614653627 -1.390085814 1.576430677 -1.938030547 0.599051948 1.138399138 FBgn0030082 HP1b Heterochromatin Protein 1b http://flybase.org/reports/FBgn0030082 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay negative regulation of heterochromatin assembly ; GO:0031452 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay chromocenter ; GO:0010369 | colocalizes_with inferred from direct assay nuclear euchromatin ; GO:0005719 | colocalizes_with inferred from direct assay "Hp1b, CG7041, HP1b, HP1B, HP1" "IPR017984:Chromo domain subgroup, IPR000953:Chromo/chromo shadow domain, IPR008251:Chromo shadow domain, IPR016197:Chromo domain-like, IPR023779:Chromo domain, conserved site, IPR023780:Chromo domain" CG7041 11-Aug-17 DroID_v2017_08 "Drer\cbx5, Drer\cbx3b, Drer\cbx1b, Drer\cbx3a, Drer\cdyl, Drer\cbx1a" - "Cele\H04D03.6, Cele\hpl-1, Cele\hpl-2" "Xtro\cbx8, Xtro\cbx1, Xtro\cbx5, Xtro\cbx3" "Mmus\Cbx3, Mmus\Cbx1, Mmus\Cdyl2, Mmus\Cdyl, Mmus\Cbx5, Mmus\Mphosph8" "Hsap\CBX3, Hsap\C15orf57, Hsap\CDY1, Hsap\CDY2A, Hsap\CDY1B, Hsap\CDYL2, Hsap\CDYL, Hsap\CBX1, Hsap\CDY2B, Hsap\CBX5, Hsap\MPHOSPH8" "partially lethal - majority die,viable,lethal" FBgn0030362 regucalcin regucalcin http://flybase.org/reports/FBgn0030362 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern lipid particle ; GO:0005811 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG1803, T1, regucalcin, Regucalcin" "IPR011042:Six-bladed beta-propeller, TolB-like, IPR005511:Senescence marker protein-30 (SMP-30), IPR013658:SMP-30/Gluconolactonase/LRE-like region" CG1803 11-Aug-17 DroID_v2017_08 "Drer\zgc:194209, Drer\rgn" Scer\YBR053C - Xtro\rgn Mmus\Rgn Hsap\RGN "viable,fertile,lethal" FBgn0030659 CG9215 - http://flybase.org/reports/FBgn0030659 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG9215 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9215 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-56e3.3, Drer\si:ch211-89o9.6" "Scer\AZF1, Scer\ZAP1" "Cele\blmp-1, Cele\Y55F3AM.14" "Xtro\gzf1, Xtro\bcl6" "Mmus\Zfp24, Mmus\Zfp445, Mmus\Zfp110, Mmus\Zfp369, Mmus\Zscan5b" "Hsap\ZNF701, Hsap\ZNF784, Hsap\ZSCAN5B, Hsap\ZSCAN5A" viable DRSC20171 I -0.060953914 -2.263476935 -1.311423958 -1.473586256 0.098476968 -0.674986586 FBgn0003071 Pfk Phosphofructokinase http://flybase.org/reports/FBgn0003071 FBgn0010618 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR009161 6-phosphofructokinase activity ; GO:0003872 | inferred from mutant phenotype fructose 6-phosphate metabolic process ; GO:0006002 | inferred from electronic annotation with InterPro:IPR022953 response to sucrose ; GO:0009744 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype glycolytic process ; GO:0006096 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR009161 6-phosphofructokinase complex ; GO:0005945 | inferred by curator from GO:0003872 "Pfk, CG4001, BcDNA.GH12192, pfk, l(2)06339, BcDNA:GH12192, PFK, PFK1" "IPR015912:Phosphofructokinase, conserved site, IPR000023:Phosphofructokinase domain, IPR009161:ATP-dependent 6-phosphofructokinase, eukaryotic-type, IPR022953:ATP-dependent 6-phosphofructokinase" CG4001 11-Aug-17 DroID_v2017_08 "Drer\pfkla, Drer\pfklb, Drer\pfkpa, Drer\pfkmb, Drer\pfkma, Drer\pfkpb" "Scer\PFK1, Scer\PFK2" "Cele\pfk-1.2, Cele\pfk-1.1" "Xtro\pfkm, Xtro\pfkp" "Mmus\Pfkm, Mmus\Pfkp, Mmus\Pfkl" "Hsap\PFKM, Hsap\PFKP, Hsap\PFKL" embryonic stage -- adult stage larval stage--adult stage "lethal,recessive,viable" "embryonic/larval somatic muscle,embryonic myoblast" FBgn0085377 CG34348 - http://flybase.org/reports/FBgn0085377 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR002123" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002123 - "CG34348, CG11757, CG15197" IPR002123:Phospholipid/glycerol acyltransferase CG34348 11-Aug-17 DroID_v2017_08 "Drer\psmd11a, Drer\tmem68" - "Cele\Y38C1AA.1, Cele\rpn-6.2, Cele\rpn-6.1" Xtro\tmem68 "Mmus\Tmem68, Mmus\Psmd11" "Hsap\PSMD11, Hsap\TMEM68" viable FBgn0037475 Fer1 48 related 1 http://flybase.org/reports/FBgn0037475 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with twi" - "CG10066, CG33323, BcDNA:RH30329, CG14611, Fer1, bHLHa30, fer1" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG33323 11-Aug-17 DroID_v2017_08 "Drer\atoh1c, Drer\tal2, Drer\ptf1a, Drer\nhlh2, Drer\tcf24, Drer\scxa, Drer\mespab, Drer\si:ch211-246m6.4, Drer\figla, Drer\tcf21, Drer\mespba, Drer\msgn1, Drer\hand2, Drer\mespaa, Drer\lyl1, Drer\neurod1, Drer\tcf15, Drer\tcf23, Drer\msc, Drer\tal1, Drer\ascl1b, Drer\ascl1a, Drer\scxb" - "Cele\hlh-13, Cele\hlh-12, Cele\hlh-15, Cele\hlh-3, Cele\lin-32" "Xtro\tcf21, Xtro\lyl1, Xtro\msc, Xtro\ferd3l, Xtro\mespb, Xtro\scx, Xtro\ascl3, Xtro\hand1, Xtro\msgn1, Xtro\figla, Xtro\nhlh1, Xtro\tal1, Xtro\tcf15, Xtro\neurod1, Xtro\ascl2, Xtro\ptf1a, Xtro\hand2, Xtro\mespa" "Mmus\Ascl5, Mmus\Ptf1a, Mmus\Hand1, Mmus\Nhlh2, Mmus\Hand2, Mmus\Tcf23, Mmus\Tcf21, Mmus\Ascl3, Mmus\Mesp1, Mmus\Tal1, Mmus\Tal2, Mmus\Msc, Mmus\Msgn1, Mmus\Ferd3l, Mmus\Ascl4, Mmus\Scx, Mmus\Neurod2, Mmus\Nhlh1, Mmus\Mesp2, Mmus\Ascl1, Mmus\Tcf15, Mmus\Lyl1, Mmus\Figla" "Hsap\NHLH1, Hsap\LYL1, Hsap\FIGLA, Hsap\SCX, Hsap\ASCL5, Hsap\MSC, Hsap\TCF15, Hsap\MESP1, Hsap\MSGN1, Hsap\TCF23, Hsap\FERD3L, Hsap\HAND2, Hsap\ASCL1, Hsap\NHLH2, Hsap\TAL1, Hsap\ASCL4, Hsap\TAL2, Hsap\PTF1A, Hsap\MESP2, Hsap\TCF21, Hsap\NEUROD2, Hsap\TCF24, Hsap\HAND1, Hsap\ASCL3" viable FBgn0015316 Try29F Trypsin 29F http://flybase.org/reports/FBgn0015316 - protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence or structural similarity serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP106, CG9564, try29F.2, try29F, Try29F" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG9564 11-Aug-17 DroID_v2017_08 "Drer\LOC103908930, Drer\si:dkey-78l4.1, Drer\si:dkey-78l4.7, Drer\si:dkey-21e2.3, Drer\si:dkey-78l4.10, Drer\gzm3, Drer\si:dkey-78l4.13, Drer\try, Drer\prss59.2, Drer\si:dkey-78l4.2, Drer\si:ch211-165b19.9, Drer\si:dkey-21e2.16" - "Cele\svh-1, Cele\rab-11.1, Cele\try-1" "Xtro\gzma, Xtro\prss2, Xtro\gzmak, Xtro\LOC100498083, Xtro\LOC101730924, Xtro\LOC496623, Xtro\try10, Xtro\LOC101730988, Xtro\LOC100498532, Xtro\prss1" "Mmus\Prss37, Mmus\1700074P13Rik, Mmus\Try4, Mmus\Klk4, Mmus\Gzma, Mmus\Gm5771, Mmus\Prss1, Mmus\Try5, Mmus\Prss55, Mmus\Prss58, Mmus\Try10, Mmus\Prss2, Mmus\Prss3, Mmus\Gzmk, Mmus\Gm2663, Mmus\Mcpt1, Mmus\2210010C04Rik, Mmus\Masp2" "Hsap\PRSS37, Hsap\GZMB, Hsap\PRSS2, Hsap\PRSS1, Hsap\PRSS58, Hsap\PRSS3, Hsap\GZMK, Hsap\PRSS57, Hsap\CMA1, Hsap\AZU1" embryonic stage | stage 16-17 embryonic/larval midgut | posterior

"viable,visible" trichogen cell FBgn0264922 smt3 smt3 http://flybase.org/reports/FBgn0264922 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with lwr inferred from physical interaction with dl protein tag ; GO:0031386 | inferred from biological aspect of ancestor with PANTHER:PTN001316528 protein sumoylation ; GO:0016925 | inferred from direct assay protein import into nucleus ; GO:0006606 | inferred from genetic interaction with lwr inferred from physical interaction with dl dendritic spine morphogenesis ; GO:0060997 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype protein desumoylation ; GO:0016926 | inferred from genetic interaction with velo cellular response to transforming growth factor beta stimulus ; GO:0071560 | inferred from genetic interaction with dpp mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype positive regulation of MAP kinase activity ; GO:0043406 | inferred from mutant phenotype cellular protein modification process ; GO:0006464 | inferred from genetic interaction with lwr inferred from physical interaction with dl dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype positive regulation of MyD88-dependent toll-like receptor signaling pathway ; GO:0034126 | inferred from mutant phenotype central nervous system projection neuron axonogenesis ; GO:0021952 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype positive regulation of protein localization to plasma membrane ; GO:1903078 | inferred from mutant phenotype tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay "condensed nuclear chromosome ; GO:0000794 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay condensed chromosome outer kinetochore ; GO:0000940 | inferred from direct assay condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay" "smt3, SUMO, Smt3, sumo, SMT3, DmSmt3, DmSUMO-1, Dm0342, Dmsmt3, dSmt3, l(2)04493, anon-EST:Posey240, CG4494, Sumo, dsmt3, l(2)SH0182, l(2)SH2 0182" "IPR033950:Sumo domain, IPR000626:Ubiquitin domain, IPR022617:Rad60/SUMO-like domain, IPR029071:Ubiquitin-related domain" CG4494 11-Aug-17 DroID_v2017_08 "Drer\sumo2b, Drer\sumo3b, Drer\sumo3a, Drer\sumo2a, Drer\sumo1, Drer\nfatc2ip" Scer\SMT3 Cele\smo-1 "Xtro\sumo1, Xtro\sumo2, Xtro\sumo3" "Mmus\Sumo2, Mmus\Nfatc2ip, Mmus\Sumo3, Mmus\Sumo1" "Hsap\SUMO1, Hsap\UBE2G2, Hsap\SUMO2, Hsap\NFATC2IP, Hsap\SUMO3, Hsap\SUMO4" embryonic stage && larval stage && adult stage embryonic stage " cell

, organism

" DRSC03611 IK 0.986455357 2.195064602 0.494406179 -0.926324009 1.551299802 0.091238662 FBgn0036336 ste14 isoprenylcysteine carboxylmethyltransferase http://flybase.org/reports/FBgn0036336 protein_coding_gene "protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity ; GO:0004671 | inferred from electronic annotation with InterPro:IPR007269, InterPro:IPR025770" "C-terminal protein methylation ; GO:0006481 | inferred from electronic annotation with InterPro:IPR007269, InterPro:IPR025770" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007269 endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR025770 "ste14, Dmel\Ste14, Ste14, CG11268" "IPR025770:Protein-S-isoprenylcysteine O-methyltransferase, IPR007269:Isoprenylcysteine carboxyl methyltransferase" CG11268 11-Aug-17 DroID_v2017_08 Drer\icmt Scer\STE14 "Cele\M01E11.1, Cele\icmt-1" Xtro\icmt Mmus\Icmt Hsap\ICMT viable FBgn0020312 CG4050 - http://flybase.org/reports/FBgn0020312 FBgn0015361 protein_coding_gene - biological_process ; GO:0008150 | no biological data available - "anon-j, anon-DM192, CG4050" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR013618:Domain of unknown function DUF1736, IPR019734:Tetratricopeptide repeat" CG4050 11-Aug-17 DroID_v2017_08 "Drer\ogt.1, Drer\ifit16, Drer\fkbpl, Drer\kdm6ba, Drer\ttc25, Drer\tmtc3, Drer\ifit8, Drer\spag1a, Drer\ogt.2, Drer\ifit14, Drer\tomm34, Drer\kdm6a, Drer\bbs4, Drer\kdm6al, Drer\ttc6, Drer\ifit15, Drer\ifit9, Drer\spag1b, Drer\dyx1c1" "Scer\CYC8, Scer\SWA2, Scer\TAH1" Cele\F38B6.6 "Xtro\spag1, Xtro\ttc25, Xtro\ogt, Xtro\dyx1c1, Xtro\ifit5, Xtro\kdm6b, Xtro\tmtc3, Xtro\kdm6a, Xtro\ttc16, Xtro\bbs4" "Mmus\Ttc25, Mmus\Kdm6a, Mmus\Ifit1bl2, Mmus\Ifit3, Mmus\Tomm34, Mmus\Uty, Mmus\Kdm6b, Mmus\Lonrf3, Mmus\Ttc16, Mmus\Dyx1c1, Mmus\Ifit1bl1, Mmus\Tmtc3, Mmus\Fkbpl, Mmus\Ifit3b, Mmus\Ogt, Mmus\Ifit2, Mmus\Bbs4, Mmus\Spag1, Mmus\Ifit1, Mmus\Tmtc1, Mmus\Ttc24" "Hsap\KDM6B, Hsap\IFIT1B, Hsap\UTY, Hsap\FKBPL, Hsap\TTC24, Hsap\LONRF2, Hsap\TTC32, Hsap\DYX1C1, Hsap\KDM6A, Hsap\IFIT5, Hsap\TOMM34, Hsap\IFIT3, Hsap\TTC6, Hsap\SPAG1, Hsap\IFIT1, Hsap\LONRF3, Hsap\BBS4, Hsap\TTC16, Hsap\OGT, Hsap\TMTC1, Hsap\TMTC3, Hsap\IFIT2" "partially lethal - majority die,some die during pupal stage" FBgn0030286 CG1657 - http://flybase.org/reports/FBgn0030286 protein_coding_gene guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from sequence or structural similarity with UniProtKB:Q14C86 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence model GTPase activating protein binding ; GO:0032794 | inferred from sequence or structural similarity with UniProtKB:Q14C86 guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from sequence or structural similarity with HGNC:23375 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR008936 regulation of GTPase activity ; GO:0043087 | inferred from electronic annotation with InterPro:IPR001936 regulation of protein transport ; GO:0051223 | inferred from sequence or structural similarity with UniProtKB:Q14C86 regulation of Rab protein signal transduction ; GO:0032483 | inferred from sequence model regulation of protein transport ; GO:0051223 | inferred from sequence or structural similarity with HGNC:23375 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:Q14C86 "CG1657, FBpp0073304" "IPR001936:Ras GTPase-activating protein, IPR003123:VPS9 domain, IPR008936:Rho GTPase activation protein" CG1657 11-Aug-17 DroID_v2017_08 "Drer\rabgef1l, Drer\rabgef1, Drer\gapvd1" "Scer\VPS9, Scer\MUK1" Cele\rme-6 "Xtro\rabgef1, Xtro\gapvd1" "Mmus\Rabgef1, Mmus\Gapvd1" "Hsap\RABGEF1, Hsap\GAPVD1" "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC19752 E 0.493572631 1.130857766 1.773524148 0.128008496 0.251698482 0.51142775 FBgn0046704 Liprin-alpha Liprin-alpha http://flybase.org/reports/FBgn0046704 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Liprin-γ inferred from physical interaction with Liprin-β axon target recognition ; GO:0007412 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype regulation of axon extension involved in axon guidance ; GO:0048841 | inferred from mutant phenotype anterograde synaptic vesicle transport ; GO:0048490 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from mutant phenotype retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype synaptic vesicle localization ; GO:0097479 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from direct assay "Dliprin-alpha, CG11199, oos, DLiprin, LIP.1, LIP1, Liprin-alpha, Liprin, LIP, lpr, lip-alpha, DLiprin-alpha" "IPR030442:Liprin-alpha, IPR001660:Sterile alpha motif domain, IPR029515:LAR-interacting protein, Liprin, IPR013761:Sterile alpha motif/pointed domain" CG11199 11-Aug-17 DroID_v2017_08 "Drer\kaznb, Drer\ppfia2, Drer\ppfia4, Drer\ppfia1, Drer\ppfia3, Drer\kazna" Scer\USO1 "Cele\C23H4.6, Cele\syd-2" "Xtro\ppfia2, Xtro\ppfia1, Xtro\ppfia3" "Mmus\Ppfia4, Mmus\Ppfibp1, Mmus\Ppfia1, Mmus\Ppfia3, Mmus\Ppfia2" "Hsap\PPFIA4, Hsap\PPFIBP1, Hsap\PPFIA3, Hsap\KAZN, Hsap\CDC42BPA, Hsap\PPFIA1, Hsap\PPFIA2" " embryonic stage , larval stage , embryonic stage | stage 4-17 " " embryonic peripheral nervous system

, ventral nerve cord

, embryonic/larval somatic muscle

, larval central nervous system

, embryonic central nervous system

, embryonic brain

" " larval stage , embryonic stage | stage 16,17 " " neuromuscular junction

, synapse

, neuropil ventral nerve cord

, larval central nervous system

" "neuroanatomy defective,neurophysiology defective,somatic clone,lethal,partially lethal - majority die,recessive,male sterile" "neuromuscular junction,bouton,embryonic/larval neuromuscular junction,synaptic vesicle,optic cartridge,somatic clone,eye photoreceptor cell,photoreceptor cell R7,cell non-autonomous,photoreceptor cell R4,medulla,NMJ bouton" FBgn0032236 mRpS7 mitochondrial ribosomal protein S7 http://flybase.org/reports/FBgn0032236 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R9 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q3T040 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R9 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:Q3T040 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q3T040 inferred from sequence or structural similarity with UniProtKB:Q9Y2R9 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R9 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "mRPS7, RpS7, MRP-S7, CG5108, mRpS7" "IPR000235:Ribosomal protein S5/S7, IPR023798:Ribosomal protein S7 domain" CG5108 11-Aug-17 DroID_v2017_08 "Drer\mrps7, Drer\rps5" "Scer\RSM7, Scer\RPS5" Cele\mrps-7 "Xtro\mrps7, Xtro\rps5" "Mmus\Mrps7, Mmus\Rps5" "Hsap\RPS5, Hsap\MRPS7" "viable,visible" trichogen cell FBgn0025456 CREG Cellular Repressor of E1A-stimulated Genes http://flybase.org/reports/FBgn0025456 FBgn0064909 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR012349 FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR012349 transcription factor binding ; GO:0008134 | inferred from physical interaction with Tbp protein homodimerization activity ; GO:0042803 | inferred from direct assay oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR012349 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:2351 - "dCREG, CG5413, BcDNA:LP11958, CREG, creg" "IPR014631:Cellular repressor of E1A-stimulated genes (CREG), IPR012349:FMN-binding split barrel" CG5413 11-Aug-17 DroID_v2017_08 "Drer\creg1, Drer\creg2" - - Xtro\creg1 "Mmus\Creg1, Mmus\Creg2" "Hsap\CREG2, Hsap\CREG1" viable FBgn0004896 fd59A forkhead domain 59A http://flybase.org/reports/FBgn0004896 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "Dmfd3, FD3, fd3, CG3668, fd59A, Fd59a, fd59a, FD59A, foxd" "IPR018122:Fork head domain conserved site1, IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG3668 11-Aug-17 DroID_v2017_08 "Drer\foxa3, Drer\foxk2, Drer\foxe1, Drer\foxl1, Drer\foxb2, Drer\foxa2, Drer\foxa1, Drer\foxg1a, Drer\foxc1b, Drer\foxb1b, Drer\foxb1a, Drer\zgc:194189, Drer\foxd5, Drer\foxa, Drer\foxd1, Drer\foxk1, Drer\foxq2, Drer\foxd2, Drer\foxc1a, Drer\foxe3, Drer\si:ch211-262e15.1, Drer\foxf2b, Drer\foxj1a, Drer\foxd3, Drer\zgc:162612" "Scer\HCM1, Scer\FKH1, Scer\FKH2" "Cele\fkh-6, Cele\lin-31, Cele\fkh-2, Cele\unc-130, Cele\pha-4, Cele\fkh-10" "Xtro\foxe3, Xtro\foxe1, Xtro\foxj1, Xtro\foxk2, Xtro\foxi4.2, Xtro\foxd2, Xtro\foxa2, Xtro\foxd4l1.2, Xtro\foxa4, Xtro\foxd3, Xtro\foxl1, Xtro\foxc2, Xtro\foxa1, Xtro\foxd1, Xtro\foxc1, Xtro\foxj1.2, Xtro\foxd4l1.1, Xtro\foxb1" "Mmus\Foxk1, Mmus\Foxa3, Mmus\Foxe1, Mmus\Foxs1, Mmus\Foxg1, Mmus\Foxa2, Mmus\Foxc1, Mmus\Foxd3, Mmus\Foxb1, Mmus\Foxb2, Mmus\Foxl1, Mmus\Foxd1, Mmus\Foxj1, Mmus\Foxd4, Mmus\Foxk2, Mmus\Foxd2, Mmus\Foxc2, Mmus\Foxa1" "Hsap\FOXC2, Hsap\FOXB1, Hsap\FOXS1, Hsap\FOXB2, Hsap\FOXA1, Hsap\FOXI3, Hsap\FOXD4L5, Hsap\FOXD4L4, Hsap\FOXD4L1, Hsap\FOXA2, Hsap\FOXE1, Hsap\FOXK1, Hsap\FOXK2, Hsap\FOXL1, Hsap\FOXC1, Hsap\FOXD3, Hsap\FOXD4L6, Hsap\FOXD4L3, Hsap\FOXA3, Hsap\FOXD4, Hsap\FOXG1, Hsap\FOXD1, Hsap\FOXJ1, Hsap\FOXD2" embryonic stage " larval thoracic sensillum | precursor

, ventral midline

, neuroblast

, embryonic brain

" "viable,semi-fertile" FBgn0035872 CG7185 - http://flybase.org/reports/FBgn0035872 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0000381 "CFlm-68k, cg7185, CG7185, CF I[[m]]68" IPR000504:RNA recognition motif domain CG7185 11-Aug-17 DroID_v2017_08 Drer\cpsf6 - Cele\cfim-2 "Xtro\cpsf6, Xtro\cpsf7" "Mmus\Cpsf7, Mmus\Cpsf6" "Hsap\CPSF7, Hsap\CPSF6" viable DRSC10781 I -0.63160175 -2.38956706 -1.073407435 -0.08736464 -0.749360006 -0.177486969 FBgn0034487 Efhc1.2 EF-hand domain containing 1.2 http://flybase.org/reports/FBgn0034487 protein_coding_gene - cilium assembly ; GO:0060271 | inferred from sequence model - "CG11048, Efhc1.2" "IPR006602:Uncharacterised domain DM10, IPR010554:Domain of unknown function DUF1126" CG11048 11-Aug-17 DroID_v2017_08 "Drer\efhc2, Drer\efhc1" - Cele\Y49A10A.1 "Xtro\efhc2, Xtro\efhc1" "Mmus\Efhc2, Mmus\Efhc1" "Hsap\EFHC1, Hsap\EFHC2" "viable,fertile" FBgn0036480 Cep135 Centrosomal protein 135kDa http://flybase.org/reports/FBgn0036480 protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype mitotic centrosome separation ; GO:0007100 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype ciliary basal body organization ; GO:0032053 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay ciliary basal body ; GO:0036064 | inferred from direct assay "bld10, DCep135, Cep135, CG17081, dbld10, Bld10p, DCep135/Bld10, Bld10, DmBLD10, CEP135, Bld-10" - CG17081 11-Aug-17 DroID_v2017_08 "Drer\wu:fi04e12, Drer\tsga10, Drer\evpla, Drer\evplb, Drer\dspa, Drer\ppl, Drer\cep135" - Cele\tag-278 Xtro\cep135 "Mmus\Tsga10, Mmus\Ppl, Mmus\Cep135, Mmus\Evpl" "Hsap\CEP135, Hsap\EVPL, Hsap\EVPLL, Hsap\TSGA10, Hsap\PPL" "female fertile,male sterile,recessive,viable,meiotic cell cycle defective,male,visible" "spermatozoon,primary spermatocyte,centriole | progressive,spermatid axoneme,centrioleBrd15),interphase microtubule organizing centerBrd15),neuroblast,mitotic spindleBrd15),centrioleED218),chaeta" FBgn0033657 Sln Silnoon http://flybase.org/reports/FBgn0033657 protein_coding_gene monocarboxylic acid transmembrane transporter activity ; GO:0008028 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 monocarboxylic acid transport ; GO:0015718 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 integral component of plasma membrane ; GO:0005887 | inferred from sequence model basolateral plasma membrane ; GO:0016323 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "Sln, CG8271" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8271 11-Aug-17 DroID_v2017_08 "Drer\slc16a6b, Drer\slc16a13, Drer\slc16a1b, Drer\slc16a8, Drer\slc16a5b, Drer\slc16a7, Drer\slc16a12a, Drer\LOC103911912, Drer\slc16a6a, Drer\slc16a3, Drer\zgc:165507, Drer\slc16a5a, Drer\slc16a12b, Drer\slc16a4, Drer\slc16a1a, Drer\slc16a9a, Drer\zgc:114041, Drer\pdap1a, Drer\si:ch211-234h8.7, Drer\slc16a9b, Drer\si:dkey-246g23.4" "Scer\MCH5, Scer\MCH4, Scer\MCH2, Scer\ATG22, Scer\ESBP6" "Cele\mct-6, Cele\mct-5" "Xtro\slc16a2, Xtro\slc16a13, Xtro\slc16a7, Xtro\slc16a3, Xtro\slc16a5, Xtro\slc16a9, Xtro\slc16a6, Xtro\slc16a12, Xtro\slc16a1" "Mmus\Slc16a11, Mmus\Slc16a14, Mmus\Slc16a12, Mmus\Slc16a8, Mmus\Slc16a3, Mmus\Slc16a13, Mmus\Slc16a5, Mmus\Slc16a1, Mmus\Slc16a6, Mmus\Slc16a9, Mmus\Slc16a4, Mmus\Slc16a7" "Hsap\SLC16A3, Hsap\SLC16A5, Hsap\SLC16A10, Hsap\SLC16A7, Hsap\SLC16A9, Hsap\SLC16A12, Hsap\SLC16A8, Hsap\SLC16A11, Hsap\SLC16A13, Hsap\SLC16A1, Hsap\SLC16A6, Hsap\SLC16A14, Hsap\SLC16A4" "increased cell death,small body,lethal - all die before end of larval stage,some die during larval stage,viable" wing disc FBgn0041181 Tep3 Thioester-containing protein 3 http://flybase.org/reports/FBgn0041181 protein_coding_gene "endopeptidase inhibitor activity ; GO:0004866 | inferred from electronic annotation with InterPro:IPR001599, InterPro:IPR002890" defense response to other organism ; GO:0098542 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR011626 "Tep3, dTEPIII, CG7068, TEP3mel, TEP3, TepIII, TEPIII" "IPR002890:Alpha-2-macroglobulin, N-terminal, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR009048:Alpha-macroglobulin, receptor-binding, IPR011625:Alpha-2-macroglobulin, N-terminal 2, IPR011626:Alpha-macroglobulin complement component, IPR019742:Alpha-2-macroglobulin, conserved site, IPR013783:Immunoglobulin-like fold, IPR019565:Alpha-2-macroglobulin, thiol-ester bond-forming, IPR001599:Alpha-2-macroglobulin" CG7068 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-46g23.2, Drer\c3a.2, Drer\a2ml, Drer\c4, Drer\c3b.1, Drer\c3b.2, Drer\si:dkey-8k3.2, Drer\c3a.4, Drer\c3a.3, Drer\c3a.6, Drer\c3a.1, Drer\cd109, Drer\si:dkey-52d15.2, Drer\cpamd8, Drer\c5, Drer\zgc:165518, Drer\zgc:171426" - Cele\tep-1 "Xtro\ovos2, Xtro\c4a, Xtro\a2ml1, Xtro\c3, Xtro\cd109, Xtro\c5" "Mmus\AI182371, Mmus\C4b, Mmus\BC048546, Mmus\C3, Mmus\Mug2, Mmus\Hc, Mmus\A2m, Mmus\Cd109" "Hsap\C4B_2, Hsap\C4A, Hsap\C5, Hsap\C3, Hsap\A2M, Hsap\C4B, Hsap\CPAMD8, Hsap\PZP, Hsap\CD109, Hsap\A2ML1" "viable,fertile,immune response defective" DRSC03452 E 0.113856801 -0.701503109 3.343495256 0.977988176 0.490349447 0.107022181 FBgn0002643 mam mastermind http://flybase.org/reports/FBgn0002643 "FBgn0010581, FBgn0026797" protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from electronic annotation with InterPro:IPR019082 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from electronic annotation with InterPro:IPR019082 Notch signaling pathway ; GO:0007219 | inferred from electronic annotation with InterPro:IPR019082 asymmetric cell division ; GO:0008356 | inferred from mutant phenotype heart morphogenesis ; GO:0003007 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype ventral midline development ; GO:0007418 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement mesodermal cell fate determination ; GO:0007500 | inferred from mutant phenotype nervous system development ; GO:0007399 | non-traceable author statement somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement nuclear speck ; GO:0016607 | inferred from electronic annotation with InterPro:IPR019082 nucleus ; GO:0005634 | inferred from sequence or structural similarity inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "mam, CG8118, Mam, dMam, Dm0064, mam(CAG)[[7]], SR2-4, N-2G, l(2)04615, l(2)03505, MAM, MamH" "IPR019082:Neurogenic mastermind-like, N-terminal" CG8118 11-Aug-17 DroID_v2017_08 "Drer\ncoa3, Drer\maml3" - - - - - " embryonic stage | gastrula , adult stage && oogenesis stage | stage S10 , larval stage | late , larval stage , pupal stage | early , embryonic stage | 2-16 hr , embryonic stage | gastrula | early , embryonic stage | cellular blastoderm , embryonic stage | stage 13-17 , embryonic stage | contracted germ band , embryonic stage | stage 8 , embryonic stage | 8-16 hr , embryonic stage | extended germ band , embryonic stage | stage 6 , embryonic stage | stage 6-8 , embryonic stage | 0-2 hr , embryonic stage | 16 hr , embryonic stage | stage 13 , adult stage && oogenesis stage | early , embryonic stage | 5 hr " " anterior midgut proper primordium

, follicle cell

, dorsal mesothoracic disc

, endoderm | presumptive

,

ubiquitous , ventral nerve cord

, cephalic furrow

, oocyte

, inclusive hindgut primordium

, nurse cell

, mesoderm | presumptive

, ventral thoracic disc

, ectoderm | ventral

, germ band

, central nervous system | restricted

, eye-antennal disc

, morphogenetic furrow | anterior to

, mesectoderm

, ventral furrow

, ventral neurogenic region | restricted

, larval brain

, posterior midgut proper primordium

, embryonic/larval digestive system | rudiment

, embryonic/larval foregut

, ventral midline

, ventral nerve cord | segmentally repeated pattern

" " larval stage | third instar , embryonic stage | stage 17 , embryonic stage | stage 14-15 , embryonic stage | stage 9-17 , embryonic stage | stage 8 , embryonic stage | stage 11 , embryonic stage | stage >8 , embryonic stage | stage 7-8 , adult stage && oogenesis stage , embryonic stage | stage 9-10 , embryonic stage | gastrula , embryonic stage | blastoderm , embryonic stage | stage 14-17 " " neuroblast

, embryonic/larval hindgut

, central nervous system

, optic lobe

, embryonic/larval salivary gland

, ventral neurogenic region

, inclusive hindgut primordium

, mesoderm

, mesectoderm

, antenno-maxillary complex | restricted

, epidermis

, ventral midline

, dorsal mesothoracic disc

, embryonic/larval hindgut | presumptive

, ventral nerve cord | restricted

, embryonic/larval esophagus

, embryonic/larval midgut

, follicle cell

, Malpighian tubule

, neuroblast MP2

, anterior midgut proper primordium

, ectoderm

, cephalic furrow

, subesophageal ganglion

, embryonic/larval foregut

, embryonic/larval proventriculus

, eye-antennal disc

, posterior midgut proper primordium

,

ubiquitous , larval brain

, embryonic/larval pharynx

, ventral nerve cord

, ventral thoracic disc

, epidermis

lateral & dorsal " "visible,dominant,neuroanatomy defective,lethal,recessive,viable,fertile,lethal - all die before end of embryonic stage,neurogenic phenotype,some die during embryonic stage,somatic clone,male sterile,female sterile,partially lethal - majority die,chemical sensitive,homeotic,heat sensitive" "wing,posterior midline glial cell,midline glial cell,supernumerary,embryo,germline clone,maternal effect,VUM motorneuron,VUM interneuron,H-cell sib,H-cell,neuroblast MNB,presumptive embryonic/larval central nervous system,embryonic/larval cuticle,vMP2 neuron,RP2sib neuron,pCC neuron,segmental nerve,intersegmental nerve,anterior fascicle & synapse | supernumerary,germline cell,male,RP2 motor neuron,ectopic,anterior,wing vein L3,wing vein L5,presumptive embryonic/larval peripheral nervous system,olfactory receptor neuron,antennal lobe glomerulus DL4,adult olfactory receptor neuron Or49a/85f,antennal lobe glomerulus VL1,antennal lobe glomerulus VM4,antennal lobe glomerulus VC3l,antennal lobe glomerulus VM1,antennal lobe glomerulus VC3,antennal lobe glomerulus VC1,antennal lobe glomerulus VA4,antennal lobe glomerulus VC2,antennal lobe glomerulus VC4,antennal lobe glomerulus DL1,antennal lobe glomerulus DM1,antennal lobe glomerulus V,antennal lobe glomerulus DM4,antennal lobe glomerulus DM2,antennal lobe glomerulus DM3,antennal lobe glomerulus DA4l,antennal lobe glomerulus DC1,antennal lobe glomerulus DA3,antennal lobe glomerulus DA1,wing vein,eye,macrochaeta,U neuron,wing vein L2,wing vein L4,ventral nerve cord,embryonic/larval somatic muscle,embryonic/larval dorsal vessel,precursor,nervous system,heart primordium,ectoderm,embryonic epidermis,dorsal cluster neuron,medulla,stomatogastric nervous system primordium,ventral,lateral,somatic clone,ommatidium,eye photoreceptor cell,pigment cell,cuticle & macrochaeta | somatic clone,interommatidial bristle,trichogen cell,tormogen cell,thecogen cell,wing margin,ovary,multidendritic neuron,A-subperineurial glial cell,B-subperineurial glial cell of abdomen,lateral ventral subperineurial glial cell,presumptive embryonic/larval nervous system,embryonic myoblast,egg chamber,follicle stem cell,embryonic labral segment & embryonic epidermis,embryonic labial segment & embryonic epidermis,embryonic hypopharynx & epidermis,embryonic maxillary segment & embryonic epidermis,larval head,denticle belt,aCC neuron,dMP2 neuron,Usib neuron,neuroblast,microchaeta,tendon cell,antenna,morphogenetic furrow,wing margin bristle,scutellar bristle,notopleural bristle,posterior notopleural bristle,heat sensitive,female germline stem cell,germarium cap cell,embryonic/larval neuron,sensory mother cell,mesothoracic tergum,apterous-expressing neuron of the lateral cluster of the thorax,embryonic heart cardioblast,embryonic pericardial cell" FBgn0039141 spas spastin http://flybase.org/reports/FBgn0039141 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 microtubule binding ; GO:0008017 | inferred from mutant phenotype microtubule-severing ATPase activity ; GO:0008568 | inferred from mutant phenotype ATPase activity ; GO:0016887 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VC57 alpha-tubulin binding ; GO:0043014 | non-traceable author statement" microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype positive regulation of lipid metabolic process ; GO:0045834 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype positive regulation of microtubule depolymerization ; GO:0031117 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from mutant phenotype regulation of synaptic plasticity ; GO:0048167 | traceable author statement transmission of nerve impulse ; GO:0019226 | traceable author statement positive regulation of microtubule depolymerization ; GO:0031117 | inferred from direct assay microtubule severing ; GO:0051013 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype positive regulation of neuromuscular synaptic transmission ; GO:1900075 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay synaptic vesicle ; GO:0008021 | colocalizes_with inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 chromosome ; GO:0005694 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay microtubule cytoskeleton ; GO:0015630 | inferred from direct assay "CG5977, D-spastin, Dspastin, spas, Spas, spastin, Spastin" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR007330:MIT, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017179:Spastin, IPR015415:Vps4 oligomerisation, C-terminal" CG5977 11-Aug-17 DroID_v2017_08 "Drer\fignl1, Drer\vps4b, Drer\katnal1, Drer\iqca1, Drer\spast, Drer\si:dkey-157g16.6, Drer\katna1, Drer\katnal2, Drer\fign, Drer\zgc:153738" "Scer\SAP1, Scer\YTA6" "Cele\vps-4, Cele\spas-1, Cele\figl-1, Cele\mei-1" "Xtro\fign, Xtro\fignl1, Xtro\katna1, Xtro\vps4b, Xtro\vps4a, Xtro\spast" "Mmus\4931409K22Rik, Mmus\Vps4a, Mmus\Katnal1, Mmus\Fignl2, Mmus\Fign, Mmus\Vps4b, Mmus\Fignl1, Mmus\Katnal2, Mmus\Spast, Mmus\Katna1" "Hsap\KATNA1, Hsap\FIGN, Hsap\IQCA1, Hsap\VPS4B, Hsap\KATNAL1, Hsap\KATNAL2, Hsap\SPAST, Hsap\FIGNL1, Hsap\VPS4A" wandering third instar larval stage NMJ bouton "neuroanatomy defective,somatic clone,visible,viable,fertile,short lived,partially lethal - majority die,flight defective,behavior defective,neurophysiology defective,sterile,flightless,locomotor behavior defective,eclosion defective,heat stress response defective,stress response defective,some die during pupal stage,lethal - all die before end of pupal stage,uncoordinated,majority die during pupal stage,gravitaxis defective,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,cell polarity defective" "ventral nerve cord,dendritic arborizing neuron,somatic clone,eye,border follicle cell,embryonic/larval neuromuscular junction | third instar larval stage,adult brain,morphogenetic furrow,embryonic/larval muscle system | larval stage,microtubule | larval stagehow-24B,bouton,leg,eye photoreceptor cell,NMJ bouton,microtubule,class IV dendritic arborizing neuron,dorsal multidendritic neuron ddaC,dendrite,supernumerary,microtubule | larval stage,synapse | third instar larval stageelav.PU,microtubuleelav.PU,bouton | third instar larval stage,cytoplasmic microtubule,neuromuscular junction | larval stage,dendriteppk.PG,embryonic/larval neuromuscular junction,embryonic/larval neuromuscular junction | larval stage,brain | adult stage,somatic muscle & microtubuleG14,class I dendritic arborizing neuron,dorsal multidendritic neuron ddaE,dendriteppk.1.9,microtubuleppk.1.9,microtubuleC57,microtubulesrp.Hemo,cytoskeletonsrp.Hemo,hemocyte" DRSC15929 IE 2.38373763 0.75372683 2.210430347 -0.064869408 -0.311043066 0.141796464 FBgn0014343 mirr mirror http://flybase.org/reports/FBgn0014343 "FBgn0013332, FBgn0013561, FBgn0013593, FBgn0016017, FBgn0017368, FBgn0020310" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with exd RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement protein homodimerization activity ; GO:0042803 | inferred from physical interaction with mirr" "dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype equator specification ; GO:0045317 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with exd inferred from sequence or structural similarity with caup equator specification ; GO:0045317 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from expression pattern inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay sensory neuron axon guidance ; GO:0097374 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR003893 "mirr, Iro-C, group F, Group F, IRO-C, iro, iro-C, Iro, mrr, DH1, Mrr, cre, De3, De1, l(3)6D1, mir, Sai, l(3)A5-3-42, l(3)69Da, l(3)69Ca, crep, CG10601, Mirr, IroC, MIRR" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR003893:Iroquois-class homeodomain protein, IPR009057:Homeobox domain-like, IPR008422:Homeobox KN domain" CG10601 11-Aug-17 DroID_v2017_08 "Drer\mkxa, Drer\irx3a, Drer\irx3b, Drer\irx5a, Drer\irx7, Drer\irx6a, Drer\meis1a, Drer\pknox1.1, Drer\meis3, Drer\irx1a, Drer\irx5b, Drer\meis2b, Drer\irx4b, Drer\tgif1, Drer\irx1b, Drer\pknox1.2, Drer\pknox2, Drer\irx4a, Drer\meis2a, Drer\irx2a" "Scer\HMRA2, Scer\MATALPHA2, Scer\CUP9, Scer\TOS8, Scer\HMLALPHA2" Cele\irx-1 "Xtro\mkx, Xtro\irx1, Xtro\meis3, Xtro\tgif2, Xtro\meis1, Xtro\irx5, Xtro\tgif1, Xtro\meis2, Xtro\pknox2, Xtro\irx2, Xtro\irx3, Xtro\irx4" "Mmus\Irx1, Mmus\Meis1, Mmus\Irx2, Mmus\Irx3, Mmus\Irx6, Mmus\Pknox1, Mmus\Irx5, Mmus\Pknox2, Mmus\Meis2, Mmus\Tgif2lx1, Mmus\Meis3, Mmus\Tgif1, Mmus\Mkx, Mmus\Tgif2lx2, Mmus\Tgif2, Mmus\Irx4" "Hsap\TGIF2-C20orf24, Hsap\MKX, Hsap\MEIS2, Hsap\TGIF2LX, Hsap\IRX5, Hsap\IRX6, Hsap\IRX3, Hsap\TGIF2LY, Hsap\TGIF2, Hsap\IRX1, Hsap\IRX4, Hsap\PKNOX2, Hsap\PKNOX1, Hsap\IRX2, Hsap\TGIF1, Hsap\MEIS1" " embryonic stage | stage 13 , larval stage | third instar , embryonic stage -- adult stage , larval stage , embryonic stage | stage 10 , adult stage && oogenesis stage , embryonic stage | stage >5 " " embryonic/larval proventriculus

, presutural bristle | precursor

, dorsal mesothoracic disc | restricted

, imaginal disc | restricted

, neuroblast

, follicle cell | restricted

, dorsal fold

, eye-antennal disc | dorsal <&> anterior

, eye-antennal disc | dorsal

, embryo | dorsal

, organism | segmentally repeated

, ventral nerve cord

, sensory mother cell

, embryo | anterior & ventral

, postalar bristle | precursor

" "locomotor behavior defective,neuroanatomy defective,lethal,recessive,visible,viable,partially lethal - majority die,lethal - all die before end of embryonic stage,some die during embryonic stage,maternal effect,lethal - all die before end of larval stage,some die during larval stage,planar polarity defective,somatic clone,some die during first instar larval stage,dominant,cell non-autonomous,some die during pupal stage" "abdominal ventral multidendritic neuron vdaB,germarium,egg operculum,egg chamber,dorsal appendage,alula,macrochaeta & adult thorax,wing,chorion,anterior postalar bristle,posterior supraalar bristle,ommatidium,maternal effect,scutellar bristle,haltere,chorion | anterior | maternal effect,embryo,somatic clone,eye equator,ectopic,eye,dorsal,scutum,dendrite,presutural bristle,antennal disc,posterior,postalar bristle,tergite,cell autonomous,dorsal margin photoreceptor,denticle belt,embryonic abdominal segment,eye disc,follicle cell,embryonic/larval thoracic/abdominal ventral sensory cluster,dendritescE1x6,egg,trichogen cell" FBgn0029687 Vap33 VAMP-associated protein 33kDa http://flybase.org/reports/FBgn0029687 protein_coding_gene FFAT motif binding ; GO:0033149 | inferred from electronic annotation with InterPro:IPR030229 protein localization to endoplasmic reticulum ; GO:0070972 | inferred from electronic annotation with InterPro:IPR030229 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype synapse maturation ; GO:0060074 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement terminal button organization ; GO:0072553 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype synaptic vesicle priming ; GO:0016082 | non-traceable author statement axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype phosphatidylinositol metabolic process ; GO:0046488 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR016763 endoplasmic reticulum ; GO:0005783 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay synaptic vesicle ; GO:0008021 | non-traceable author statement endomembrane system ; GO:0012505 | inferred from direct assay "vap-33A, CG5014, DVAP-33A, VAP-33-1, l(1)G0231, clone 2.42, anon-EST:Liang-2.42, BcDNA:GM03307, anon-WO03040301.124, Vap-33-1, Vap33-1, dVAP33A, VAP, VAP-33, VAPB, dVAP, VAP33-A, DVAP33A, vap33-1, dvap33a, DVAP, dvap, Vap33, Vap-33A" "IPR000535:Major sperm protein (MSP) domain, IPR008962:PapD-like, IPR016763:Vesicle-associated membrane-protein-associated protein, IPR013783:Immunoglobulin-like fold, IPR030229:Vesicle-associated membrane protein-associated protein A" CG5014 11-Aug-17 DroID_v2017_08 "Drer\vapb, Drer\vapa, Drer\vapal" "Scer\SCS2, Scer\SCS22" "Cele\Y53C10A.15, Cele\ZC196.2, Cele\F42G2.5, Cele\W08E3.4, Cele\Y38F2AR.10, Cele\F54H5.3, Cele\Y116A8A.2, Cele\Y116A8A.7, Cele\vpr-1, Cele\F58E6.5" "Xtro\mospd2, Xtro\vapb, Xtro\vapa, Xtro\mospd3" "Mmus\Vapa, Mmus\Vapb, Mmus\Mospd3" "Hsap\VAPA, Hsap\VAPB, Hsap\MOSPD3" "neuroanatomy defective,majority die during pupal stage,locomotor rhythm defective,viable,visible,lethal - all die before end of larval stage,some die during larval stage,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,recessive,neurophysiology defective,uncoordinated,increased cell death,flight defective,fertile,partially lethal - majority die,male,female,heat sensitive,size defective" "terminal bouton,neuromuscular junction,microtubule,nucleus,synapse,synapseC57,nucleusC57,somatic muscle,eye,photoreceptor cell,ommatidium,NMJ bouton,macrochaeta,bouton,mushroom body alpha-lobe,wing disc,endoplasmic reticulumC5,trichogen cell,mesothoracic tergum,NMJ bouton | larval stage,indirect flight muscle,synapseC164,bouton & microtubuleC164,bouton & microtubule,interommatidial bristle,supernumerary,eye photoreceptor cell,endoplasmic reticulumelav.PU,endoplasmic reticulumC57" FBgn0002413 dco discs overgrown http://flybase.org/reports/FBgn0002413 "FBgn0011349, FBgn0011508, FBgn0024895, FBgn0027967, FBgn0028129" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein binding ; GO:0005515 | inferred from physical interaction with Bdbt kinase activity ; GO:0016301 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with per protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype regulation of ecdysteroid secretion ; GO:0007555 | inferred from mutant phenotype cellular response to light stimulus ; GO:0071482 | inferred from direct assay protein phosphorylation ; GO:0006468 | traceable author statement positive regulation of cell division ; GO:0051781 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 regulation of protein import into nucleus ; GO:0042306 | traceable author statement circadian rhythm ; GO:0007623 | traceable author statement regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype cell communication ; GO:0007154 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype inferred from physical interaction with per endocytosis ; GO:0006897 | inferred from biological aspect of ancestor with PANTHER:PTN000226268 rhythmic behavior ; GO:0007622 | traceable author statement circadian rhythm ; GO:0007623 | inferred from direct assay locomotor rhythm ; GO:0045475 | non-traceable author statement behavioral response to cocaine ; GO:0048148 | non-traceable author statement phosphorylation ; GO:0016310 | inferred from direct assay eclosion rhythm ; GO:0008062 | traceable author statement behavioral response to cocaine ; GO:0048148 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype sleep ; GO:0030431 | non-traceable author statement protein autophosphorylation ; GO:0046777 | inferred from direct assay positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from direct assay negative regulation of protein phosphorylation ; GO:0001933 | inferred from mutant phenotype imaginal disc growth ; GO:0007446 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype cytoplasm ; GO:0005737 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "dco, CK1epsilon, DBT, dbt, Dbt, CKIepsilon, DBT/CK1epsilon, ddbt, ck1epsilon, DCO/CKIe, CG2048, l(3)j3B9, l(3)discs overgrown, l(3)S144701, l(3)S053813, 1460/09, 1447/01, 1396/02, 0915/10, 0538/13, l(3)dco, dco-1, l(3)discs overgrown-1, l(3)dco-1, l(3)rK215, dCKIepsilon, Dco/CK1, DCO, Dco, CK1delta/epsilon" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG2048 11-Aug-17 DroID_v2017_08 "Drer\ttbk1a, Drer\csnk1da, Drer\csnk1e, Drer\vrk3, Drer\csnk1db, Drer\ttbk2b, Drer\vrk2, Drer\csnk1a1, Drer\ttbk1b, Drer\vrk1" Scer\HRR25 "Cele\F22H10.1, Cele\kin-19, Cele\kin-20, Cele\T05C12.1, Cele\ZC373.3, Cele\F53C3.1, Cele\spe-6" "Xtro\vrk1, Xtro\csnk1e, Xtro\vrk2, Xtro\ttbk2, Xtro\csnk1d, Xtro\vrk3, Xtro\csnk1a1" "Mmus\Vrk3, Mmus\Vrk1, Mmus\Csnk1d, Mmus\Vrk2, Mmus\Csnk1e, Mmus\Ttbk2, Mmus\Csnk1a1, Mmus\Ttbk1" "Hsap\VRK1, Hsap\TTBK1, Hsap\CSNK1E, Hsap\VRK2, Hsap\CSNK1D, Hsap\TTBK2, Hsap\CSNK1A1, Hsap\LOC400927-CSNK1E, Hsap\VRK3, Hsap\CSNK1A1L" adult stage " adult lateral neuron

, photoreceptor cell

, adult brain | restricted

" "viable,size defective,fertile,circadian rhythm defective,cell polarity defective,lethal,recessive,locomotor rhythm defective,eclosion rhythm defective,cell size defective,somatic clone,cell autonomous,lethal - all die before end of pupal stage,some die during pupal stage,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,temperature conditional,partially lethal - majority die,visible,hyperplasia,wild-type,polyphasic,increased cell number,semidominant,partially lethal - majority live,behavior defective,cell death defective,flight defective,dominant,partially lethal" "wing,class IV dendritic arborizing neuron,somatic clone,ommatidium,neuron,lateral,wing disc,wing hair,cell non-autonomous,cell autonomous,crossvein,larva,imaginal disc,wing pouch,eye,vibrissae,wing vein,tarsal segment,adult external head,leg,unguis,supernumerary,larval head,dorsal organ,terminal organ,labral segment,embryonic/larval cuticle,dorsal,dorsal bridge,egg,germline clone,eye photoreceptor cell,wing margin bristle,trichogen cell,mesothoracic tergum" DRSC16929 I 1.989390382 1.027456985 0.858794289 0.581831233 -0.192138506 0.221942657 FBgn0001079 fu fused http://flybase.org/reports/FBgn0001079 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with cos protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271 smoothened signaling pathway ; GO:0007224 | traceable author statement smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from direct assay positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from mutant phenotype inferred from genetic interaction with hh positive regulation of protein ubiquitination ; GO:0031398 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | non-traceable author statement positive regulation of transcription factor import into nucleus ; GO:0042993 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | non-traceable author statement intraciliary transport ; GO:0042073 | inferred from mutant phenotype negative regulation of BMP signaling pathway ; GO:0030514 | inferred from genetic interaction with tkv inferred from genetic interaction with Dad protein phosphorylation ; GO:0006468 | non-traceable author statement" membrane ; GO:0016020 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Su(fu) Hedgehog signaling complex ; GO:0035301 | inferred from physical interaction with cos inferred from physical interaction with ci "fu, Fu, CG6551, fu[mel], Dm fu, l(1)fu, FU, dFu" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG6551 11-Aug-17 DroID_v2017_08 "Drer\stk36, Drer\ulk4" Scer\ATG1 Cele\F32D8.1 "Xtro\ulk4, Xtro\stk36" "Mmus\Ulk4, Mmus\Stk36" "Hsap\STK36, Hsap\ULK4" " adult stage , adult stage | female , embryonic stage | <= stage 11 , embryonic stage | early , larval stage " " egg chamber | subset

, organism

,

ubiquitous , germarium region 2

, imaginal disc

" adult stage " germarium region 2

, egg chamber | subset

" "visible,recessive,viable,female fertile,reduced,wild-type,tumorigenic,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,female semi-sterile,germline clone,lethal - all die before end of P-stage,some die during pharate adult stage,female sterile,somatic clone,segment polarity phenotype,hyperplasia,heat sensitive" "wing,anterior compartment,sensillum campaniformium,ectopic,wing vein,1st posterior cell,double row,wing vein L3,wing vein L4,wing basal cell 2,dil cell,egg,germline clone,embryo,ovary,denticle belt,maternal effect,embryonic ventral nervous system,blastoderm embryo,embryonic segment,proximal,Bolwig organ,germline cell,cell non-autonomous,somatic clone,posterior compartment,oocyte,egg chamber,cystoblast,supernumerary,ocellar bristle,interocellar bristle,lateral ocellus,medial ocellus,ovariole,distal,microchaeta & tarsal segment 1,microchaeta & tarsal segment 2,microchaeta & tarsal segment 3,microchaeta & tarsal segment 4,microchaeta & tarsal segment 5,macrochaeta & tarsal segment 5 | distal,mesothoracic tarsal bristle longitudinal row 4,mesothoracic tarsal bristle longitudinal row 3.5,mesothoracic tarsal bristle longitudinal row 1,mesothoracic tarsal bristle longitudinal row 5,mesothoracic tarsal bristle longitudinal row 8,mesothoracic tarsal bristle longitudinal row 2.5,wing sensillum,dorsal double row,ventral double row,sensillum campaniformium of dorsal radius,anterior crossvein,embryonic epidermis,ocellus,anterior scutellar bristle,scutellum,embryonic thorax,embryonic abdomen,interfollicle cell,polar follicle cell,nurse cell,presumptive embryonic/larval central nervous system,posterior cell,wing basal cell 1,posterior scutellar bristle,dorsal hair,segment,posterior,germarium,female germline cell" DRSC20333 I 0.490788449 -2.434819276 0.442541585 0.657667334 -0.476184012 0.097666183 FBgn0001965 Sos Son of sevenless http://flybase.org/reports/FBgn0001965 "FBgn0013235, FBgn0026802" protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 protein binding ; GO:0005515 | inferred from physical interaction with drk Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | inferred from sequence or structural similarity Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | inferred from direct assay Rac guanyl-nucleotide exchange factor activity ; GO:0030676 | inferred from genetic interaction with Rac1 "regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with robo1, Rac1, RhoGAP93B, sli torso signaling pathway ; GO:0008293 | traceable author statement positive regulation of Ras protein signal transduction ; GO:0046579 | inferred by curator from GO:0005088 positive regulation of Rac protein signal transduction ; GO:0035022 | inferred from genetic interaction with Rac1 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement sevenless signaling pathway ; GO:0045500 | traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from direct assay "sos, EK2-8, Su(tor)2-2, E(sev)2A, 34Ea, br25, l(2)br24, Sos1, EY2-3, BG:DS00941.4, l(2)34Ea, dSos, l(2)k05224, 2.3, l(2)k06321, dme-SOS, SOS, br24, l(2)br25, l(2)Sos, E(var)189, CG7793, Sos, EC2-5" "IPR000219:Dbl homology (DH) domain, IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR001849:Pleckstrin homology domain, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR007125:Histone H2A/H2B/H3, IPR011993:PH domain-like, IPR009072:Histone-fold, IPR019804:Ras guanine-nucleotide exchange factor, conserved site, IPR023578:Ras guanine nucleotide exchange factor domain" CG7793 11-Aug-17 DroID_v2017_08 "Drer\rasgrf2a, Drer\rapgef1a, Drer\si:ch211-234p18.3, Drer\sos2, Drer\LOC797658, Drer\rasgrf2b, Drer\sos1, Drer\rapgef1b" "Scer\BUD5, Scer\LTE1, Scer\CDC25, Scer\YCL068C" "Cele\pxf-1, Cele\sos-1, Cele\Y34B4A.4" "Xtro\rapgef1, Xtro\sos1, Xtro\sos2" "Mmus\Sos2, Mmus\Rapgef6, Mmus\Rasgrf1, Mmus\Sos1, Mmus\Rapgef2, Mmus\Rasgrp2, Mmus\Ralgps2, Mmus\Rasgef1b, Mmus\Rapgef1, Mmus\Rasgrf2" "Hsap\RASGRF2, Hsap\RAPGEF1, Hsap\RASGRP2, Hsap\RASGEF1B, Hsap\SOS2, Hsap\RASGRF1, Hsap\SOS1, Hsap\RAPGEF2" "visible,viable,fertile,recessive,lethal,enhancer of variegation,dominant,wild-type,mitotic cell cycle defective,cell autonomous,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,terminal phenotype,germline clone,maternal effect,body color defective" "wing,wing vein,photoreceptor cell R7,ommatidium,somatic clone,dorsal air sac primordium,pCC neuron,dMP2 neuron,vMP2 neuron,longitudinal connective,eye,ectopic,macrochaeta,commissure,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R8,eye disc,cell autonomous,midline crossing tract,embryo,germline clone,maternal effect,wing vein L4,abdominal 1 ventral monoscolopidial chordotonal organ vch1,abdominal 2 ventral monoscolopidial chordotonal organ vch1,abdominal 3 ventral monoscolopidial chordotonal organ vch1,abdominal 4 ventral monoscolopidial chordotonal organ vch1,abdominal 5 ventral monoscolopidial chordotonal organ vch1,abdominal 6 ventral monoscolopidial chordotonal organ vch1,abdominal 7 ventral monoscolopidial chordotonal organ vch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC03439 IEK -2.867508031 -6.526072224 -3.167020634 -3.67134216 -1.435347178 -2.484029732 FBgn0010341 Cdc42 Cdc42 http://flybase.org/reports/FBgn0010341 FBgn0012059 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with Whamy protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W1B0 GTPase activity ; GO:0003924 | non-traceable author statement protein kinase binding ; GO:0019901 | inferred from physical interaction with mbt protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VXE5 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from direct assay GTPase activating protein binding ; GO:0032794 | inferred from physical interaction with RacGAP84C GTPase activity ; GO:0003924 | traceable author statement protein kinase binding ; GO:0019901 | inferred from physical interaction with Pak3" "positive regulation of wound healing=0090303 |... mutant phenotype <> maintenance of protein location=0045185 |... mutant phenotype <> protein localization to plasma membrane=0072659 |... mutant phenotype <> Rho protein signal transduction=0007266 |... genetic interaction with Zir <> branching involved in open tracheal system development=0060446 |... mutant phenotype <> dendrite morphogenesis=0048813 |... mutant phenotype <> actin filament polymerization=0030041 |... mutant phenotype <> JNK cascade=0007254 | traceable author statement <> regulation of actin filament polymerization=0030833 |... mutant phenotype <> encapsulation of foreign target=0035010 |... mutant phenotype <> axon guidance=0007411 |... mutant phenotype <> actin filament polymerization=0030041 | traceable author statement <> dorsal closure=0007391 | traceable author statement <> establishment of neuroblast polarity=0045200 |... mutant phenotype <> phagocytosis=0006909 |... mutant phenotype <> maintenance of cell polarity=0030011 |... mutant phenotype <> melanotic encapsulation of foreign target=0035011 |... mutant phenotype <> axonogenesis=0007409 | traceable author statement <> regulation of cell shape=0008360 |... mutant phenotype <> actin filament organization=0007015 |... mutant phenotype <> nephrocyte filtration=0097206 |... mutant phenotype <> regulation of glucose metabolic process=0010906 |... mutant phenotype <> wound healing=0042060 |... mutant phenotype <> cellularization=0007349 | traceable author statement <> dorsal closure=0007391 |... mutant phenotype <> positive regulation of protein kinase activity=0045860 |... mutant phenotype <> transforming growth factor beta receptor signaling pathway=0007179 | traceable author statement <> neuron projection morphogenesis=0048812 |... mutant phenotype <> dorsal closure, amnioserosa morphology change=0046664 | NOT inferred from mutant phenotype <> germarium-derived egg chamber formation=0007293 |... mutant phenotype <> suture of dorsal opening=0007396 | traceable author statement <> epithelium development=0060429 |... mutant phenotype <> actin cytoskeleton reorganization=0031532 |... mutant phenotype <> cortical actin cytoskeleton organization=0030866 |... mutant phenotype <> regulation of actin filament polymerization=0030833 |... direct assay <> sensory perception of touch=0050975 |... mutant phenotype <> oogenesis=0048477 | traceable author statement <> cytoskeleton organization=0007010 | non-traceable author statement <> axon extension=0048675 |... genetic interaction with Frl <> cell projection assembly=0030031 |... mutant phenotype <> ovarian follicle cell development=0030707 | traceable author statement <> positive regulation of lamellipodium assembly=0010592 |... mutant phenotype <> spermatid development=0007286 |... mutant phenotype <> regulation of synaptic growth at neuromuscular junction=0008582 |... direct assay <> positive regulation of filopodium assembly=0051491 |... mutant phenotype <> neuromuscular synaptic transmission=0007274 |... genetic interaction with cv-c inferred from genetic interaction with Dys <> regulation of synaptic growth at neuromuscular junction=0008582 |... mutant phenotype <> vesicle-mediated transport=0016192 |... mutant phenotype <> dorsal appendage formation=0046843 |... mutant phenotype <> imaginal disc-derived wing hair outgrowth=0035318 |... mutant phenotype <> motor neuron axon guidance=0008045 |... mutant phenotype <> hemocyte migration=0035099 |... mutant phenotype <> actin cytoskeleton organization=0030036 | traceable author statement <> regulation of axonogenesis=0050770 |... genetic interaction with LIMK1 <> exocyst localization=0051601 |... mutant phenotype <> neuron projection development=0031175 |... mutant phenotype" rhabdomere ; GO:0016028 | inferred from mutant phenotype axon ; GO:0030424 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "DmCDC42, cdc42, Dcdc42, Dm Cdc42, DCdc42, CDC42, DCDC42, Cdc42Dm, D-CDC42, D-Cdc42, Dmcdc42, CG12530, Cdc42, D-cdc42, P40793" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR003578:Small GTPase superfamily, Rho type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12530 11-Aug-17 DroID_v2017_08 "Drer\rac3b, Drer\rhogd, Drer\rhoac, Drer\rhoab, Drer\cdc42l2, Drer\rnd3a, Drer\rhogc, Drer\rhobtb2a, Drer\LOC100331257, Drer\rhoq, Drer\rac1b, Drer\rac1a, Drer\cdc42, Drer\rhoj, Drer\rhof, Drer\rhoh, Drer\rhobtb2b, Drer\si:dkey-263f15.2, Drer\rhobtb1, Drer\rnd3b, Drer\rac3a, Drer\rnd1a, Drer\rnd2, Drer\rhoub, Drer\si:dkey-6b12.5, Drer\cdc42l, Drer\rhoca, Drer\si:ch211-133l11.10, Drer\rhogb, Drer\LOC100537765, Drer\rhov, Drer\rhocb, Drer\rhoga, Drer\rac1l, Drer\rhoua, Drer\rhoaa, Drer\rnd1b" "Scer\RHO2, Scer\RHO4, Scer\RHO3, Scer\RHO1, Scer\CDC42, Scer\RHO5" "Cele\crp-1, Cele\mig-2, Cele\ced-10, Cele\cdc-42" "Xtro\rhoa, Xtro\rhoa.2, Xtro\rhof, Xtro\rnd3, Xtro\rhobtb2, Xtro\rac2, Xtro\rhobtb1, Xtro\rnd1, Xtro\rhou, Xtro\rac1, Xtro\cdc42, Xtro\rhoj, Xtro\rhoc, Xtro\rhob, Xtro\rhov, Xtro\rhobtb3" "Mmus\Rac1, Mmus\4930544G11Rik, Mmus\Rac3, Mmus\Rhof, Mmus\Rhob, Mmus\Rhoh, Mmus\Rhoj, Mmus\Rhobtb2, Mmus\Rnd2, Mmus\Rhoc, Mmus\Rhobtb1, Mmus\Rhog, Mmus\Rnd3, Mmus\Rhod, Mmus\Rhou, Mmus\Rnd1, Mmus\Rhobtb3, Mmus\Rhov, Mmus\Rhoa, Mmus\Cdc42, Mmus\Rhoq, Mmus\Rac2" "Hsap\RHOC, Hsap\RND3, Hsap\RHOJ, Hsap\RND1, Hsap\RHOBTB1, Hsap\RHOH, Hsap\CDC42, Hsap\RAC2, Hsap\RHOD, Hsap\RHOU, Hsap\RHOBTB3, Hsap\RHOQ, Hsap\RHOB, Hsap\RHOBTB2, Hsap\RHOG, Hsap\RAC1, Hsap\RHOA, Hsap\RAC3, Hsap\RHOV, Hsap\RND2, Hsap\RHOF" " embryonic stage | stage 10-12 , embryonic stage , embryonic stage | blastoderm , embryonic stage -- adult stage " " somatic mesoderm

, embryonic central nervous system

, embryonic/larval digestive system

,

ubiquitous " "male sterile,wild-type,visible,lethal,recessive,cell shape defective,planar polarity defective,somatic clone,wound healing defective,lethal - all die before end of embryonic stage,maternal effect,partially,some die during embryonic stage,neuroanatomy defective,cell polarity defective,decreased cell size,viable,size defective,immune response defective,non-rescuable maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,touch sensitivity defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,female,partially lethal - majority die,neurophysiology defective,chemical sensitive,chemical resistant" "spermatid cyst,seminal vesicle,head cyst cell,actin filamentT155,nurse cell,eye,ommatidium,photoreceptor,pigment cell,rhabdomere,interommatidial bristle,anterior crossvein,ectopic,follicle cell,somatic clone,wing,crossvein,embryo,maternal effect,nurse cell ring canal,germline clone,actin filament | germline clone | maternal effect,vertical system neuron,oocyte,dendrite | ectopic,dendritic spine,axon,terminal tracheal cell,eye photoreceptor cell,retina,embryonic/larval pericardial cell,dorsal closure embryo,embryonic epidermis,ventral,embryonic/first instar larval cuticle,anterior,presumptive embryonic/larval central nervous system,longitudinal connective,embryonic hemocyte,macrophage,nurse cell & actin filament | germ-line clone | maternal effect,proventriculus inner layer primordium,proventriculus intermediate layer primordium,embryonic proventriculus,ganglionic branch primordium,neuroblast,wing hair,supernumerary,actin filament & rhabdomere | somatic clone,neuromuscular junction,bouton,embryonic/larval neuromuscular junction,NMJ bouton,microchaeta & wingptc-559.1,wing disc,anterior/posterior compartment boundary,dorsal,embryonic hemocyte & leading edgePxn.PS, crq.PA,embryonic/larval dorsal trunk,embryonic/larval somatic muscle,myotube,muscle attachment site,microchaeta,wing vein,wing margin,wing margin bristle,heat sensitive,medial triple row,cell non-autonomous,presumptive embryonic/larval tracheal system,antenna & glial cellMz317,antenna & sensory neuronMz317,embryonic/larval midgut | embryonic stage,dorsal appendage,abdominal segmental nerve,neuroblast | embryonic stage,neuromuscular junctionMhc.Switch.PO,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage1003.3,neuron,abdominal posterior fascicle neuron & growth cone & filopodiumelav.PLu,mesothoracic les3 neuron & growth cone & filopodiumelav.PLu,metathoracic les3 neuron & growth cone & filopodiumelav.PLu,dendrite | dorsal | embryonic stage60,presumptive embryonic/larval peripheral nervous system,dorsal multidendritic neuron | embryonic stage,dorsal multidendritic neuron & dendrite & embryo60,abdominal intersegmental nerve,dorsal abdominal cluster,dendrite,somatic muscle,antennal commissure,antennal lobe glomerulus,glomerulus,mesothoracic leg disc,aCC neuron & dendriteeve.RN2,RP2 neuron & dendriteeve.RN2,RP2 motor neuron,RP2 neuron & neuriteeve.RN2,RP2 neuron & cell bodyeve.RN2,pCC neuron,dMP2 neuron,vMP2 neuron,midline crossing tract | embryonic stage 16,ventral nerve cord commissure | embryonic stage 16,macrochaeta & metathoracic laterotergiteBx-MS1096,microchaeta & metathoracic laterotergiteBx-MS1096,motor neuron,growth coneelav.PLu,tergal depressor of trochanter muscle motor neuron & dendriteshakB.lethal.4.1,giant fiber neuron,eye disc,growth cone,neurite,giant axon,anterior embryonic/larval midgut,aCC neuron,neuromuscular junctionC57,epithelium,female germline cyst" FBgn0260442 rhea rhea http://flybase.org/reports/FBgn0260442 protein_coding_gene actin filament binding ; GO:0051015 | inferred from electronic annotation with InterPro:IPR006077 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR015224 insulin receptor binding ; GO:0005158 | inferred from electronic annotation with InterPro:IPR002404 protein binding ; GO:0005515 | inferred from physical interaction with wech actin binding ; GO:0003779 | inferred from sequence or structural similarity integrin binding ; GO:0005178 | inferred from physical interaction with mys "cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from electronic annotation with InterPro:IPR015224 cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity muscle attachment ; GO:0016203 | inferred from mutant phenotype cardiac muscle cell-cardiac muscle cell adhesion ; GO:0086042 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cell adhesion ; GO:0007155 | traceable author statement germ-band shortening ; GO:0007390 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype" cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 ruffle ; GO:0001726 | inferred from electronic annotation with InterPro:IPR015224 focal adhesion ; GO:0005925 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from sequence or structural similarity "rhea, talin, Talin, CG6831, CT21159, Tln, Rhea, tendrils" "IPR029071:Ubiquitin-related domain, IPR006077:Vinculin/alpha-catenin, IPR002558:I/LWEQ domain, IPR015009:Vinculin-binding site-containing domain, IPR019748:FERM central domain, IPR015224:Talin, central, IPR002404:IRS-type PTB domain, IPR019747:FERM conserved site, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019749:Band 4.1 domain, IPR018979:FERM, N-terminal, IPR000299:FERM domain, IPR032425:Talin, N-terminal F0 domain" CG6831 11-Aug-17 DroID_v2017_08 "Drer\tln2a, Drer\mesdc1, Drer\tln2b, Drer\tln1" Scer\SLA2 Cele\tln-1 "Xtro\mesdc1, Xtro\tln2" "Mmus\Tln1, Mmus\Tln2, Mmus\Mesdc1" "Hsap\TLN1, Hsap\TLN2, Hsap\MESDC1" " embryonic stage | stage 12 , embryonic stage | stage 6 , embryonic stage | stage 16 " " ventral nervous system

, organism | ubiquitous

, embryonic midgut

, muscle attachment site

" " embryonic stage | stage 12 , larval stage | third instar , embryonic stage | stage 16 , embryonic stage | stage 6 " " anterior midgut proper primordium && posterior midgut proper primordium

, dorsal mesothoracic disc | restricted

, muscle attachment site

,

" "viable,lethal,visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "egg chamber,conditional,muscle attachment site,germline clone,presumptive embryonic/larval muscle system,muscle cell,tendon cell,muscle cell & actin filament & embryo,tendon cell & microtubule & embryo,muscle cell & focal adhesion & embryo,tendon cell & focal adhesion & embryo,tendon cell & basal lamina & embryo,somatic clone,actin filament & follicle cell | somatic clone,embryonic/larval midgut primordium,embryonic proventriculus,germ band,rescuable maternal effect,terminal tracheal cell,oocyte,cell non-autonomous,gastric caecum primordium,wing,embryonic/larval somatic muscle,eye,embryonic/larval tracheal system,embryonic/larval fat body branch,border follicle cell" FBgn0000022 ac achaete http://flybase.org/reports/FBgn0000022 - protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da sequence-specific DNA binding ; GO:0043565 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from physical interaction with da sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000358347 DNA binding ; GO:0003677 | traceable author statement RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with l(1)sc" "neuroblast fate determination ; GO:0007400 | traceable author statement peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype central nervous system development ; GO:0007417 | traceable author statement epithelial cell proliferation involved in Malpighian tubule morphogenesis ; GO:0061331 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | non-traceable author statement regulation of neurogenesis ; GO:0050767 | inferred from biological aspect of ancestor with PANTHER:PTN000358354 regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with l(1)sc oogenesis ; GO:0048477 | traceable author statement ventral cord development ; GO:0007419 | non-traceable author statement sensory organ development ; GO:0007423 | inferred from mutant phenotype nervous system development ; GO:0007399 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | traceable author statement Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay RNA polymerase II transcription factor complex ; GO:0090575 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 transcription factor complex ; GO:0005667 | inferred from physical interaction with da "ac, Hw, Ac, EG:125H10.3, CG3796, 990 E5 F1, T5, AS-C T5, AS-C T5ac, ascT5, sc/T5, ASC, AC, AS-C" "IPR015660:Achaete-scute transcription factor-related, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG3796 11-Aug-17 DroID_v2017_08 "Drer\ascl1a, Drer\ascl1b" - "Cele\hlh-14, Cele\hlh-4, Cele\hlh-3" Xtro\ascl2 "Mmus\Ascl1, Mmus\Ascl3, Mmus\Ascl2" "Hsap\ASCL2, Hsap\ASCL5, Hsap\ASCL3, Hsap\ASCL4, Hsap\ASCL1" " embryonic stage , larval stage , embryonic stage | stage 9 , larval stage | third instar , embryonic stage | stage 8 " " stomodeum

, neuroblast

, sensory mother cell

, posterior embryonic/larval midgut

, proneural cluster

, embryonic stomatogastric nervous system

, neuroblast

{ $ N* } , neurogenic region

, neurectoderm

{ $ E(spl)* } , sensory organ cell

, dorsal mesothoracic disc | restricted

, ventral midline

, ectoderm

, procephalic segment

, larval optic lobe | presumptive

, procephalic neuroblast

, embryonic central nervous system

, dorsal mesothoracic disc

, neurectoderm

{ $ Dl* } , neurectoderm

{ $ neur* } , cephalic furrow

, embryonic peripheral nervous system

, labral segment

, ventral neurogenic region

, neurectoderm

{ $ bib* } " " larval stage | third instar , larval stage , embryonic stage | stage 9-11 , embryonic stage | stage 8-9 , embryonic stage , embryonic stage | stage 8 , embryonic stage | stage 8-10 , embryonic stage | stage 8-11 , embryonic stage | stage 9 , wandering third instar larval stage " " dorsal mesothoracic disc

, sensory mother cell

, protocerebral neuroblast | subset

, neuroblast NB3-5

, neurectoderm

{ $ neur* } , proneural cluster

, neurectoderm

{ $ bib* } , neuroblast NB7-4

, wing vein L5

, ectoderm

, deuterocerebral neuroblast | subset

, neuroblast NB7-1

, neuroblast MP2

, procephalic neuroblast | subset

, wing vein L1

{ + h* } , ventral neurogenic region

, wing vein L3

{ + h* } , procephalic neurogenic region | restricted

, neuroblast

{ $ N* } , neurectoderm

{ $ E(spl)* } , neurectoderm

{ $ Dl* } , dorsal mesothoracic disc | dorsal/ventral compartment boundary & restricted " "visible,dominant,recessive,viable,good,wild-type,male sterile,fertile,male fertile,female sterile" "external sensory organ,ectopic,scutellum,wing vein L3,macrochaeta & head,macrochaeta & thorax,sensillum campaniformium,microchaeta,mesothoracic tarsal bristle,mesothoracic metatarsus,macrochaeta,glial cell,wing & nerve,nerve,third segment of antenna,mesothoracic tergum & macrochaeta | ectopic,wing margin bristle,anterior orbital bristle,anterior notopleural bristle,humeral bristle,postvertical bristle,ocellar bristle,presutural bristle,anterior postalar bristle,anterior supraalar bristle,posterior postalar bristle,posterior supraalar bristle,scutellar bristle,dorsocentral bristle,acrostichal bristle,supernumerary,anterior dorsocentral bristle,posterior dorsocentral bristle,microchaeta & mesothoracic pleurum,microchaeta & wing,macrochaeta & abdominal tergite,microchaeta & pleural membrane,interocellar bristle,interommatidial bristle,mesothoracic leg sensillum,posterior notopleural bristle,microchaeta & scutum,microchaeta & scutellum,sensillum campaniformium of proximal dorsal radius,sense organ & wing vein,precursor,macrochaeta & leg,microchaeta & leg,adult thorax & microchaeta,scutum,wing,microchaeta & mesothoracic tergum | supernumerary,neuron,anterior sternopleural bristle,wing vein,posterior crossvein,chaeta,sensory mother cell,sensory mother cell & dorsal mesothoracic disc" DRSC18734 I -1.740211892 -2.639558744 0.435517917 1.190294363 0.396568427 0.114040713 FBgn0026404 Dronc Death regulator Nedd2-like caspase http://flybase.org/reports/FBgn0026404 "FBgn0025326, FBgn0062102" protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity with WB:WBGene00000417 inferred from direct assay cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay endopeptidase activity ; GO:0004175 | inferred from direct assay cysteine-type endopeptidase activity involved in apoptotic signaling pathway ; GO:0097199 | inferred from direct assay cysteine-type endopeptidase activity involved in apoptotic signaling pathway ; GO:0097199 | contributes_to inferred from direct assay cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:0097200 | inferred from biological aspect of ancestor with PANTHER:PTN000825206 protein homodimerization activity ; GO:0042803 | inferred from direct assay CARD domain binding ; GO:0050700 | inferred from sequence model hemocyte development ; GO:0007516 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway ; GO:2001269 | inferred from direct assay programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype inferred from genetic interaction with Ca-β metamorphosis ; GO:0007552 | traceable author statement programmed cell death ; GO:0012501 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype apoptotic process ; GO:0006915 | traceable author statement head involution ; GO:0008258 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement regulation of retinal cell programmed cell death ; GO:0046668 | non-traceable author statement nurse cell apoptotic process ; GO:0045476 | inferred from genetic interaction with Strica apoptotic process ; GO:0006915 | inferred from mutant phenotype zymogen activation ; GO:0031638 | inferred from direct assay inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | non-traceable author statement execution phase of apoptosis ; GO:0097194 | inferred from biological aspect of ancestor with PANTHER:PTN000825206 central nervous system development ; GO:0007417 | inferred from mutant phenotype melanization defense response ; GO:0035006 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype inferred from genetic interaction with Diap1 inferred from physical interaction with Diap1 protein autoprocessing ; GO:0016540 | inferred from direct assay compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from direct assay regulation of cell death ; GO:0010941 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from genetic interaction with Atg1 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of compound eye retinal cell programmed cell death ; GO:0046672 | inferred from mutant phenotype apoptotic process ; GO:0006915 | non-traceable author statement activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from expression pattern inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern protein heterooligomerization ; GO:0051291 | inferred from direct assay mitochondrion ; GO:0005739 | NOT inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay apoptosome ; GO:0043293 | inferred from direct assay "Dronc, DRONC, dronc, CG8091, caspase-9, anon-EST:GreesD6, anon-EST:GressD6, anon-WO0118547.313, Nc, Dronc/Casp9, CG8090, Nc\Dronc" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR011029:Death-like domain, IPR015917:Peptidase C14A, caspase catalytic domain, IPR017350:Peptidase C14A, interleukin-1 beta convertase type, IPR029030:Caspase-like domain, IPR033139:Peptidase family C14A, cysteine active site" CG8091 11-Aug-17 DroID_v2017_08 "Drer\LOC798445, Drer\casp8l2, Drer\caspb, Drer\casp3b, Drer\caspxa, Drer\pycard, Drer\gbp3, Drer\casp3a, Drer\LOC101886133, Drer\casp8l1, Drer\casp9, Drer\casp2, Drer\caspbl, Drer\cflara, Drer\zgc:194469, Drer\si:ch211-195h23.3, Drer\caspa, Drer\casp7, Drer\pea15, Drer\zgc:171731, Drer\casp8, Drer\si:dkey-103e21.5, Drer\casp6, Drer\LOC100331324" - "Cele\csp-2, Cele\csp-1, Cele\csp-3, Cele\ced-3" "Xtro\casp9, Xtro\casp6, Xtro\casp7, Xtro\LOC733553, Xtro\casp3, Xtro\casp2, Xtro\pea15, Xtro\casp10, Xtro\casp1" "Mmus\Casp4, Mmus\Casp12, Mmus\Casp2, Mmus\Casp14, Mmus\Cflar, Mmus\Casp1, Mmus\Casp8, Mmus\Gpr89, Mmus\Casp3, Mmus\Casp9, Mmus\Pea15a, Mmus\Casp7, Mmus\Casp6" "Hsap\CASP1, Hsap\CASP14, Hsap\CASP10, Hsap\CFLAR, Hsap\CASP9, Hsap\CASP3, Hsap\PEA15, Hsap\GPR89B, Hsap\GPR89A, Hsap\CASP8, Hsap\CARD8, Hsap\CASP5, Hsap\CASP4, Hsap\CASP12, Hsap\CASP2, Hsap\CASP7, Hsap\CARD17, Hsap\CASP6, Hsap\CARD18, Hsap\CARD16" " adult stage && oogenesis stage , embryonic stage -- adult stage , larval stage | third instar , embryonic stage | early " " egg chamber

, eye disc

, embryonic/larval midgut

,

ubiquitous , embryonic/larval salivary gland

, larval brain

" "visible,lethal - all die before end of P-stage,some die during pharate adult stage,eye color defective,lethal - all die before end of pupal stage,temperature conditional,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,increased cell death,lethal - all die before end of embryonic stage,decreased cell death,some die during embryonic stage,female sterile,male sterile,partially,partially lethal - majority die,decreased cell number,lethal,recessive,maternal effect,neuroanatomy defective,short lived,cell death defective,developmental rate defective,melanotic necrosis,cell shape defective,viable,fertile,increased cell number,somatic clone,rescuable maternal effect,chemical resistant,size defective,lethal - all die before end of larval stage,some die during larval stage,male,wild-type" "eye,pigment cell,ommatidium,eye disc,temperature conditional,adult head,eye disc | third instar larval stage,spermatid,cystic bulge,waste bag,spermatogonial cyst,male germline cell,eye photoreceptor cell,eye disc | P-stage,embryonic/larval Malpighian tubule,retina,wing,dorsal multidendritic neuron ddaC,dendrite477,posterior,embryonic/larval fat body | wandering third instar larval stage,neuron,inter-ommatidial precursor cell,supernumerary,salivary gland | pupal stage,postalar bristle,dendriteppk.1.9,retinal pigment cell,melanotic mass,embryonic/larval digestive system,somatic clone,eye-antennal disc,eye disc posterior to the morphogenetic furrow,embryonic/larval hemocyte,imaginal disc,embryonic/larval brain,ventral nerve cord primordium,rescuable maternal effect,ventral trunk epidermis primordium,dorsal ridge primordium,Bolwig organ,ventral nerve cord,ommatidial precursor cluster,embryonic/larval midgut,dendrite,imaginal disc epithelial cell,neuron & ventral nerve cord | ectopic,macrochaeta,sensory mother cell,eo neuron,thecogen cell,embryonic head,arista,egg chamber,male genitalia,neuroblast & larval abdominal segment 3 | late third instar larval stage,neuroblast & larval abdominal segment 4 | late third instar larval stage,neuroblast & larval abdominal segment 5 | late third instar larval stage,neuroblast & larval abdominal segment 6 | late third instar larval stage,neuroblast & larval abdominal segment 7 | late third instar larval stage,embryonic/larval salivary gland | P-stage,embryonic/larval neuromuscular junction,midline glial cell,maternal effect,presumptive embryonic/larval central nervous system,scolopidial neuron,peptidergic neuron,ectopic,cell autonomous,germline clone" FBgn0001308 Khc Kinesin heavy chain http://flybase.org/reports/FBgn0001308 "FBgn0021886, FBgn0021889, FBgn0028613" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | traceable author statement tropomyosin binding ; GO:0005523 | inferred from physical interaction with Tm1 microtubule motor activity ; GO:0003777 | inferred from direct assay motor activity ; GO:0003774 | non-traceable author statement microtubule binding ; GO:0008017 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity" "axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype stress granule disassembly ; GO:0035617 | inferred from mutant phenotype mitochondrion distribution ; GO:0048311 | inferred from mutant phenotype maintenance of cell polarity ; GO:0030011 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype microtubule sliding ; GO:0051012 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype centrosome separation ; GO:0051299 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype microtubule polymerization ; GO:0046785 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from direct assay transport along microtubule ; GO:0010970 | inferred from direct assay dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | inferred from mutant phenotype skeletal muscle fiber development ; GO:0048741 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype intracellular distribution of mitochondria ; GO:0048312 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | non-traceable author statement intracellular protein transport ; GO:0006886 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype eye photoreceptor cell differentiation ; GO:0001754 | inferred from genetic interaction with DCTN1-p150 mitochondrion transport along microtubule ; GO:0047497 | inferred from mutant phenotype actin filament bundle organization ; GO:0061572 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype establishment of nucleus localization ; GO:0040023 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | traceable author statement cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | traceable author statement" actin cap ; GO:0030478 | inferred from direct assay mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from direct assay microtubule plus-end ; GO:0035371 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay microtubule ; GO:0005874 | "Khc, KHC, kinesin, khc, KIN, DK, DKH, CG7765, l(2)W12, DmKHC, l(2R)W12, Kin, l(2)k13314, Dmkin, kin, l(2)k13219, pgs, kinesin-1, Kinesin-1, DmK, KIF 5A, Kin-1, KIF5B, KIF5" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7765 11-Aug-17 DroID_v2017_08 "Drer\kif3b, Drer\kif5c, Drer\kif5aa, Drer\kif3a, Drer\kif5ba, Drer\LOC100333558, Drer\kif5bb, Drer\kif3cb, Drer\kif5ab" "Scer\KIP2, Scer\SMY1" "Cele\unc-116, Cele\ZC262.7" "Xtro\kif5a, Xtro\kif5b, Xtro\kif5c, Xtro\kif3c, Xtro\kif3b" "Mmus\Kif5a, Mmus\Kif3b, Mmus\Kif3c, Mmus\Kif5b, Mmus\Kif3a, Mmus\Kif5c" "Hsap\KIF5B, Hsap\KIF5A, Hsap\KIF3B, Hsap\KIF5C, Hsap\KIF3C" adult stage head

", oogenesis stage && adult stage | female , larval stage | third instar , oogenesis stage | stage S8-10A , adult stage && oogenesis stage , embryonic stage " " germarium && oogonial cell

, female germline stem cell

, egg chamber | early & oogonial cell

ubiquitous , photoreceptor cell | apical

, oocyte | posterior

, stage S8 oocyte | anterior & dorsal && stage S9 oocyte | anterior & dorsal && stage S10A oocyte | anterior & dorsal , nurse cell

, oocyte

,

ubiquitous , follicle cell

" "paralytic,short lived,flightless,developmental rate defective,locomotor behavior defective,neurophysiology defective,lethal - all die before end of larval stage,heat sensitive,some die during larval stage,lethal,recessive,neuroanatomy defective,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,mitotic cell cycle defective,cytokinesis defective,wild-type,partially lethal - majority die,behavior defective,visible,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,germline clone,body color defective,majority die during third instar larval stage,majority die during pupal stage" "eye,somatic clone,ommatidium,embryonic/larval neuromuscular junction | larval stage,dendrite,dorsal appendage,germline clone,maternal effect,embryonic/larval brain,microtubule,oocyte,microtubule | germline clone,mitochondrion,oocyte & nucleus | germ-line clone,lateral transverse muscle,eye photoreceptor cell,rhabdomere,eye photoreceptor cell & endoplasmic reticulum | somatic clone,eye photoreceptor cell & multivesicular body | somatic clone,macrochaeta,microchaeta,scutellar bristle,adult cuticle & scutellar bristle | somatic clone,embryo,stage S9 oocyte & nucleus | germ-line clone,pole plasm,pole plasm | germline clone,nurse cell fusome,mitochondrial cloud | germline clone,follicle cell & mitochondrion | germ-line clone,germline cyst & mitochondrion | germ-line clone,microtubule & oocyte | oogenesis stage S9 | germ-line clone,class IV dendritic arborizing neuron,axon,neuromuscular junction,embryonic/larval nervous system,posterior fascicle & axon,axonw+),axonwvco),oocyte nucleus,chorion | germline clone,trichogen cell,mesothoracic tergum,peripheral nervous system,mitochondrionrepo.PL, repo,embryonic/larval glial cell,embryonic/larval wrapping glial cell of the eye disc | third instar larval stage,embryonic/larval peripheral nervous system | third instar larval stage" FBgn0004597 CycC Cyclin C http://flybase.org/reports/FBgn0004597 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KTX8 inferred from physical interaction with UniProtKB:Q9VW47 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from direct assay chaeta development ; GO:0022416 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of phosphorylation of RNA polymerase II C-terminal domain ; GO:1901409 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype snRNA 3'-end processing ; GO:0034472 | inferred from direct assay positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype sex comb development ; GO:0045498 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity "cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from direct assay inferred from physical interaction with kto, skd, Cdk8" "cyclinC, DmcycC, Cln3, dTRAP33, cycC, SRB11, CG7281, Cyc-C, CycC, dCycC, CG1C_DROME, CYCC, Cyclin C" "IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like, IPR028367:Cyclin C/cyclin-like subunit Ssn8, IPR031658:Cyclin, C-terminal domain 2" CG7281 11-Aug-17 DroID_v2017_08 Drer\ccnc Scer\SSN8 Cele\cic-1 Xtro\ccnc Mmus\Ccnc Hsap\CCNC " oogenesis stage && adult stage | female , embryonic stage -- adult stage , embryonic stage | early " ovary

"viable,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,visible,partially lethal - majority die" "sex comb,adult sense organ,leg,somatic clone - Minute background,sex comb tooth,somatic clone,prothoracic tarsal segment,mesothoracic bristle,mesothoracic tergum,trichogen cell" DRSC16619 K 0.588044502 0.203202611 -1.445716611 -0.000306956 1.677540876 1.166520197 FBgn0022734 l(1)3Ai lethal (1) 3Ai http://flybase.org/reports/FBgn0022734 - gene - - - "l[4], l(1)3Ai" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" polytene chromosome FBgn0011760 ctp cut up http://flybase.org/reports/FBgn0011760 "FBgn0015619, FBgn0015650, FBgn0027256, FBgn0027271, FBgn0027293, FBgn0028265, FBgn0028273, FBgn0028298, FBgn0028309, FBgn0028322, FBgn0028337, FBgn0040189, FBgn0066852" protein_coding_gene "dynein light intermediate chain binding ; GO:0051959 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V9Y9 protein homodimerization activity ; GO:0042803 | inferred from direct assay dynein intermediate chain binding ; GO:0045505 | inferred from physical interaction with sw ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with egg" sperm individualization ; GO:0007291 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype spermatid nucleus elongation ; GO:0007290 | inferred from mutant phenotype microtubule anchoring at centrosome ; GO:0034454 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype positive regulation of neuron remodeling ; GO:1904801 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic dynein complex ; GO:0005868 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay dynein complex ; GO:0030286 | inferred from direct assay dynein complex ; GO:0030286 | inferred from sequence or structural similarity "ddlc1, dlc, LC8, CG6998, Ddlc-1, Cdlc1, Ddlc1, l(1)G0153, l(1)G0207, l(1)G0204, l(1)G0248, l(1)G0338, l(1)G0387, l(1)G0371, l(1)G0432, l(1)G0445, l(1)G0244, Dlc, anon-WO03040301.128, ctp, Ctp, DLC8, lincRNA.S8635" "IPR001372:Dynein light chain, type 1/2, IPR019763:Dynein light chain, type 1/2, conserved site" CG6998 11-Aug-17 DroID_v2017_08 "Drer\dynll2a, Drer\dnal4a, Drer\dynll2b, Drer\dynll1, Drer\dnal4b" Scer\DYN2 "Cele\dlc-4, Cele\dlc-1, Cele\dlc-2, Cele\dlc-3, Cele\dlc-5" "Xtro\dynll2, Xtro\dnal4, Xtro\dynll1" "Mmus\Dynll2, Mmus\Dnal4, Mmus\Dynll1, Mmus\BC048507" "Hsap\DNAL4, Hsap\DYNLL1, Hsap\DYNLL2" " embryonic stage | late , adult stage && oogenesis stage | stage >S10 , adult stage && oogenesis stage , embryonic stage -- adult stage , pupal stage , adult stage , embryonic stage " " chordotonal organ

, oocyte

, nurse cell

, embryonic central nervous system

, head

,

ubiquitous " " embryonic stage , oogenesis stage "

ubiquitous "viable,female sterile,visible,behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,heat sensitive,recessive,partially lethal - majority live,male sterile,male fertile,poor,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,male semi-sterile,partially,wild-type,neuroanatomy defective,mitotic cell cycle defective,increased cell death" "scutum & macrochaeta,scutum & microchaeta,head & macrochaeta,macrochaeta,wing,wing vein,spermatid cyst,seminal vesicle,spermatozoon,spermatocyte fusome,wing & macrochaeta,ovariole,egg chamber,cystic bulge,actin filament bundle & nucleus,actin filament & spermatid,chaeta,salivary gland,lysosome | pupal stage,NMJ bouton,spermatid,nucleus & spermatid,scutum & macrochaeta & embryo,scutum & microchaeta & embryo,embryonic head & macrochaeta,leg & macrochaeta & embryo,sensory neuron,prothoracic femoral chordotonal organ & axon & pupa,longitudinal connective,commissure,prothoracic femoral chordotonal organ & axon,mesothoracic femoral chordotonal organ & axon,metathoracic femoral chordotonal organ & axon,astral microtubule,embryonic/larval neuroblast,astral microtubuleJC70),synaptonemal complex | somatic clone,somatic clone,ganglion mother cell,trichogen cell,tormogen cell,posterior compartment,wing disc" DRSC18758 IEK -2.163120436 -2.113667213 -1.500222659 -0.219841598 1.654270586 0.277847269 FBgn0037001 ND-39 NADH dehydrogenase (ubiquinone) 39 kDa subunit http://flybase.org/reports/FBgn0037001 protein_coding_gene coenzyme binding ; GO:0050662 | inferred from electronic annotation with InterPro:IPR001509 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:Q16795 NADH dehydrogenase activity ; GO:0003954 | inferred from biological aspect of ancestor with PANTHER:PTN000252522 "ubiquinone-6 biosynthetic process ; GO:1901006 | inferred from biological aspect of ancestor with PANTHER:PTN000252522 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:Q16795" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:Q16795 "CG6020, GM13757p, NDUFA9, NUEM, ND-39, Ndufa9" "IPR001509:NAD-dependent epimerase/dehydratase, IPR016040:NAD(P)-binding domain" CG6020 11-Aug-17 DroID_v2017_08 Drer\ndufa9a - Cele\Y53G8AL.2 Xtro\ndufa9 Mmus\Ndufa9 Hsap\NDUFA9 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0267548 CR45888 - http://flybase.org/reports/FBgn0267548 non_protein_coding_gene - - - CR45888 - CR45888 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016884 l(2)39DEi lethal (2) 39DEi http://flybase.org/reports/FBgn0016884 - gene - - - "D241, l(2)39DEi" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0267294 CR45730 - http://flybase.org/reports/FBgn0267294 non_protein_coding_gene - - - CR45730 - CR45730 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001033 Fs(3)Dam Female sterile (3) Damasa http://flybase.org/reports/FBgn0001033 - gene - embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype - "Dam, Fs(3)Damasa, Fs(3)Sz7, Fs(3)Dam" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0264364 CG43816 - http://flybase.org/reports/FBgn0264364 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43816 - CG43816 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0028994 saguaro saguaro http://flybase.org/reports/FBgn0028994 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - saguaro - - 11-Aug-17 DroID_v2017_08 - - - - - - dendrite | dorsal | embryonic stage FBgn0266228 CR44923 - http://flybase.org/reports/FBgn0266228 non_protein_coding_gene - - - "CR44923, lincRNA.672" - CR44923 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0259941 ttd5 TRPL translocation defect 5 http://flybase.org/reports/FBgn0259941 protein_coding_gene - - - ttd5 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0002999 omm ommatoreductum http://flybase.org/reports/FBgn0002999 - gene - - - omm - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,visible,recessive" "ommatidium,eye,adult head,head bristle,maxillary palpus,macrochaeta & adult thorax,wing" FBgn0260271 GSd466 - http://flybase.org/reports/FBgn0260271 gene - - - GSd466 - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0024353 H217 H217 http://flybase.org/reports/FBgn0024353 - gene - - - H217 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,neuroanatomy defective,recessive" "optic lobe,medulla neuropil,medulla,proximal,lamina,distal,lobula plate" FBgn0036483 CG12316 - http://flybase.org/reports/FBgn0036483 protein_coding_gene - "histone H4-K16 acetylation ; GO:0043984 | inferred from electronic annotation with InterPro:IPR026711 male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype" MSL complex ; GO:0072487 | inferred from electronic annotation with InterPro:IPR026711 CG12316 IPR026711:Protein male-specific lethal-1 CG12316 11-Aug-17 DroID_v2017_08 "Drer\msl1b, Drer\msl1a" - - - Mmus\Msl1 Hsap\MSL1 "song defective,partially lethal - majority die,some die during pupal stage" embryonic/larval hemocyte | third instar larval stage DRSC09879 K 0.23269485 0.430565511 0.046557753 0.788846029 1.687490338 0.010109736 FBgn0024555 flfl falafel http://flybase.org/reports/FBgn0024555 FBgn0038169 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with mira phagocytosis ; GO:0006909 | inferred from mutant phenotype neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype "protein phosphatase 4 complex ; GO:0030289 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from physical interaction with Cenp-C nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay CENP-A containing nucleosome ; GO:0043505 | colocalizes_with inferred from direct assay" "CG9351, l(3)L4179, flfl, PP4R3, Ppp4R3, Flfl" "IPR006887:Domain of unknown function DUF625, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR011993:PH domain-like" CG9351 11-Aug-17 DroID_v2017_08 "Drer\ppp4r3b, Drer\smek1" Scer\PSY2 Cele\smk-1 "Xtro\ppp4r3b, Xtro\ppp4r3a" "Mmus\Smek1, Mmus\4930415L06Rik, Mmus\Smek2, Mmus\4932429P05Rik" "Hsap\PPP4R3A, Hsap\PPP4R3B" "viable,fertile,lethal,recessive,female fertile,poor,visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during third instar larval stage,decreased cell number,some die during larval stage,cell cycle defective" "wing,wing vein,mesothoracic tergum,neuroblast,cell" DRSC16474 IE -0.95830043 -2.070318391 -0.746483781 -3.562944432 0.019560106 0.750596516 FBgn0032475 Sfmbt Scm-related gene containing four mbt domains http://flybase.org/reports/FBgn0032475 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012313 protein binding ; GO:0005515 | inferred from physical interaction with Scm methylated histone binding ; GO:0035064 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay chromatin silencing ; GO:0006342 | inferred from direct assay imaginal disc growth ; GO:0007446 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from genetic interaction with Scm PcG protein complex ; GO:0031519 | inferred from physical interaction with pho nucleus ; GO:0005634 | inferred from direct assay "Sfmbt, SFMBT, dSfmbt, CG16975, dSFMBT" "IPR001660:Sterile alpha motif domain, IPR004092:Mbt repeat, IPR012313:Zinc finger, FCS-type, IPR013761:Sterile alpha motif/pointed domain" CG16975 11-Aug-17 DroID_v2017_08 "Drer\mbtd1, Drer\l3mbtl2" - "Cele\lin-61, Cele\mbtr-1" Xtro\mbtd1 "Mmus\Mbtd1, Mmus\L3mbtl2" "Hsap\MBTD1, Hsap\L3MBTL2" "tumorigenic,lethal - all die before end of larval stage,some die during third instar larval stage,lethal" "imaginal disc,female germline stem cell" FBgn0040080 pins partner of inscuteable http://flybase.org/reports/FBgn0040080 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P20353 protein binding ; GO:0005515 | inferred from physical interaction with Gαi inferred from physical interaction with mud GDP-dissociation inhibitor activity ; GO:0005092 | inferred from direct assay protein domain specific binding ; GO:0019904 | inferred from physical interaction with cno regulation of G-protein coupled receptor protein signaling pathway ; GO:0008277 | inferred from electronic annotation with InterPro:IPR024804 asymmetric cell division ; GO:0008356 | inferred from direct assay establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | traceable author statement asymmetric cell division ; GO:0008356 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype maintenance of protein location ; GO:0045185 | non-traceable author statement basal protein localization ; GO:0045175 | traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement establishment of spindle orientation ; GO:0051294 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | traceable author statement asymmetric protein localization ; GO:0008105 | traceable author statement establishment of mitotic spindle localization ; GO:0040001 | traceable author statement neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from direct assay apical cortex ; GO:0045179 | traceable author statement apical cortex ; GO:0045179 | inferred from direct assay cell cortex ; GO:0005938 | traceable author statement cell cortex ; GO:0005938 | inferred from direct assay apical part of cell ; GO:0045177 | non-traceable author statement "pins, Pins, PINS, CG5692, rapsyn, rad, Rad, raps, Raps" "IPR003109:GoLoco motif, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR024804:G-protein-signalling modulator 1" CG5692 11-Aug-17 DroID_v2017_08 "Drer\ogt.1, Drer\gpsm2, Drer\LOC558761, Drer\gpsm1a, Drer\gpsm2l, Drer\gpsm1b" - Cele\ags-3 "Xtro\ttc28, Xtro\gpsm2, Xtro\gpsm1" "Mmus\Ttc24, Mmus\Pcp2, Mmus\Gpsm2, Mmus\Gpsm1, Mmus\Gpsm3" "Hsap\GPSM3, Hsap\PCP2, Hsap\TTC28, Hsap\GPSM1, Hsap\GPSM2" embryonic stage " neuroblast

, mitotic domain 9

" "viable,visible,mitotic cell cycle defective,neuroanatomy defective,cell polarity defective,tumorigenic,cell cycle defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "ganglion mother cell GMC4-2a,tormogen cell,mitotic domain 9 & spindle,RP2 motor neuron,ectopic,RP2sib neuron,neuroblast,mitotic cell cycle & spindle,embryonic neuroblast & spindle,centrosome,larval brain & neuroblast,mitotic domain 9 & epithelial cell,spindle,aster,spindle & larval neuroblast,embryonic/larval neuroblast,spindle & external sensory organ precursor cell I,embryonic neuroblast,wing margin,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0024662 l(2)k06501 lethal (2) k06501 http://flybase.org/reports/FBgn0024662 - gene - - - "65/1, l(2)k06501" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" imaginal disc FBgn0261430 CR42647 - http://flybase.org/reports/FBgn0261430 non_protein_coding_gene - - - "CR42647, CR41487" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0022304 l(1)L48.3 lethal (1) L48.3 http://flybase.org/reports/FBgn0022304 - gene - - - "L48.3, l(1)L48.3" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053286 CG33286 - http://flybase.org/reports/FBgn0053286 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12982, CG33286" "IPR022110:Casc1 domain, IPR031826:Cancer susceptibility candidate 1, N-terminal" CG33286 11-Aug-17 DroID_v2017_08 Drer\casc1 - Cele\K09E2.2 - Mmus\Casc1 Hsap\CASC1 viable DRSC26119 K 0.267726939 0.083941492 0.491397888 0.335642288 2.721093434 1.641308951 FBgn0014919 anon-72ABc anon-72ABc http://flybase.org/reports/FBgn0014919 - gene - - - anon-72ABc - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0015317 U2af35 U2 small nuclear riboprotein auxiliary factor 35 http://flybase.org/reports/FBgn0015317 FBgn0012029 gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from direct assay" nucleoplasm ; GO:0005654 | inferred from direct assay "U2AF-35kDa, U2AF, U2AF[35], U2af35" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0030102 SmydA-9 "SET and MYND domain containing, arthropod-specific, member 9" http://flybase.org/reports/FBgn0030102 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "lincRNA.971, SmydA-9, CG12119" IPR001214:SET domain CG12119 11-Aug-17 DroID_v2017_08 "Drer\smyd1b, Drer\smyd4, Drer\smyd1a, Drer\smyd3, Drer\smyd2b, Drer\smyd2a" "Scer\SET5, Scer\SET6" "Cele\set-10, Cele\set-18, Cele\set-14" "Xtro\smyd4, Xtro\smyd1, Xtro\smyd5" "Mmus\Smyd2, Mmus\Smyd5, Mmus\Smyd3, Mmus\Smyd1, Mmus\Smyd4" "Hsap\SMYD2, Hsap\SMYD4, Hsap\SMYD3, Hsap\SMYD5, Hsap\SMYD1" "viable,fertile" FBgn0016977 spen split ends http://flybase.org/reports/FBgn0016977 "FBgn0010537, FBgn0016056, FBgn0016624, FBgn0022059, FBgn0022080, FBgn0022115, FBgn0026182, FBgn0031230, FBgn0040065, FBgn0047291, FBtr0078121, FBpp0077780, FBtr0078122, FBpp0077781, FBtr0078123, FBpp0077782" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from biological aspect of ancestor with PANTHER:PTN000573351 "transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype establishment of thoracic bristle planar orientation ; GO:0048106 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype maintenance of imaginal disc-derived wing hair orientation ; GO:0035321 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000573351 glial cell fate determination ; GO:0007403 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with arm inferred from genetic interaction with hid inferred from genetic interaction with wg neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Splitends, CG18497, rno, EK2-9, E(Sev-CycE)2A, EY2-7, spe, E(E2F)2A, l(2)k08102, l(2)k07612, l(2)k06805, l(2)03350, poc, 136/24, yip1, En(yan[ACT])2-7, E(Raf)2A, BcDNA:GM01870, spen, SPEN, Spen" "IPR000504:RNA recognition motif domain, IPR010912:Spen paralogue/orthologue C-terminal, metazoa, IPR012921:Spen paralogue and orthologue SPOC, C-terminal, IPR016194:SPOC-like, C-terminal domain, IPR034174:SHARP, RNA recognition motif 3, IPR015943:WD40/YVTN repeat-like-containing domain, IPR034175:SHARP, RNA recognition motif 4, IPR034173:SHARP, RNA recognition motif 2" CG18497 11-Aug-17 DroID_v2017_08 "Drer\spen, Drer\rbm15b, Drer\wu:fb69f10, Drer\rbm15" "Scer\MRN1, Scer\NRD1" "Cele\din-1, Cele\cec-8" "Xtro\rbm15, Xtro\rbm15b" "Mmus\Spen, Mmus\Rbm15b, Mmus\Rbm15" "Hsap\RBM15B, Hsap\RBM15, Hsap\SPEN" " embryonic stage | 0-24 hr , embryonic stage , embryonic stage | 2-24 hr " " embryonic stage | stage 9-14 , embryonic stage , embryonic stage | stage >=3 , larval stage " " embryonic central nervous system

, embryonic epidermis

, organism

, eye disc

, ventral thoracic disc

, dorsal mesothoracic disc

" "lethal,recessive,immune response defective,wound healing defective,viable,fertile,visible,neuroanatomy defective,cell polarity defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "ommatidium,eye photoreceptor cell,hemocyte,plasmatocyte,crystal cell,macrochaeta,scutellar bristle,ectopic,dorsocentral bristle,tormogen cell,embryonic/larval central nervous system,neurite | pharate adult stage,midline glial cell,commissure,longitudinal connective,central nervous system,presumptive embryonic/larval peripheral nervous system,germline clone,presumptive embryonic/larval central nervous system,abdominal lateral pentascolopidial chordotonal organ lch5,intersegmental nerve,transverse nerve,abdominal segmental nerve,wing vein,somatic clone,crossvein,wing hair,wing margin bristle,microchaeta,head & cuticle | ectopic,embryonic thorax,embryonic thorax & cuticle,embryonic head,hypostomal sclerite,lch5 neuron,ventral midline,ventral nerve cord commissure,motor neuron,embryonic/larval somatic muscle,sclerite,embryonic mesothoracic segment & sclerite | ectopic,embryonic metathoracic segment & sclerite | ectopic,sclerite & embryonic abdominal segment | ectopic,mouth hooks,median tooth,dental sclerite,epipharyngeal sclerite,dorsal bridge,lateral process,embryonic epidermis,sclerite & embryonic head,chordotonal organ & axon | lateral,ventral thoracic disc,denticle belt,embryonic/first instar larval cuticle,eye,mesothoracic tergum,trichogen cell" FBgn0024250 brk brinker http://flybase.org/reports/FBgn0024250 "FBtr0071048, FBpp0071007" protein_coding_gene "RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with dsx" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype salivary gland boundary specification ; GO:0007432 | non-traceable author statement wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype regulation of BMP signaling pathway ; GO:0030510 | traceable author statement negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype nervous system development ; GO:0007399 | non-traceable author statement negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | non-traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from direct assay posterior Malpighian tubule development ; GO:0061328 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement "brk, Brk, CG9653, ssg-1, Dm brk, BRK" "IPR018586:Brinker DNA-binding domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG9653 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 12 , embryonic stage | stage 13 , larval stage | third instar , embryonic stage | stage 10 , embryonic stage | stage 9-11 , embryonic stage | stage 11 , embryonic stage | stage 14 , embryonic stage | early " " embryonic/larval midgut

, parasegment 5 &&of endoderm

, dorsal mesothoracic disc | restricted

, mesoderm | ventral

, dorsal mesothoracic disc | anterior

, ventral nerve cord primordium

, endoderm | restricted

, dorsal mesothoracic disc | posterior

, tracheal pit | vicinity of

, parasegment 5 &&of visceral mesoderm

, visceral mesoderm | restricted

, ectoderm | ventral

, ventral thoracic disc | restricted

, ectoderm | ventro-lateral

" larval stage | third instar " dorsal mesothoracic disc | posterior

, dorsal mesothoracic disc | anterior

" "partially lethal - majority die,lethal,recessive,visible,dominant,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,cell autonomous,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,increased cell number,increased cell death,viable,partially,cell lethal,decreased cell number,mitotic cell cycle defective,cell non-autonomous,size defective,female semi-fertile,female fertile,partially lethal,some die during larval stage" "wing vein,ectopic,salivary gland,adult salivary gland primordium,denticle belt,commissure,longitudinal connective,embryonic/larval epidermis,embryonic head,wing,egg operculum,somatic clone,dorsal appendage,cell autonomous,hypostomal sclerite,crystal cell,neuroblast,ventral abdominal cluster,lateral,wing disc,dorsal hair,embryonic epidermis,ventral neurectoderm,dorsal,ventral,maternal effect,neuroblast NB2-4,neuroblast NB3-3,neuroblast NB4-2,neuroblast NB6-4,neuroblast NB7-3,neuroblast NB7-4,dorsal ectoderm,embryonic ventral epidermis,abdominal 1 ventral denticle belt,wing vein L4,wing vein L5,posterior crossvein,crossvein,posterior,wing blade,cardioblast,presumptive embryonic/larval peripheral nervous system,dorsal abdominal cluster,lateral abdominal cluster,embryonic/first instar larval cuticle,heat sensitive,imaginal disc,posterior compartment,cell non-autonomous,medial,eye,morphogenetic furrow,wing margin,micropyle | somatic clone,alula" FBgn0000320 eya eyes absent http://flybase.org/reports/FBgn0000320 "FBgn0000623, FBgn0004612, FBgn0063692, FBtr0079334, FBpp0078963, FBtr0079335, FBpp0078964" protein_coding_gene "protein tyrosine phosphatase activity, metal-dependent ; GO:0030946 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with so phosphoprotein phosphatase activity ; GO:0004721 | inferred from mutant phenotype protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay" "innate immune response ; GO:0045087 | inferred from genetic interaction with DNaseII positive regulation of DNA repair ; GO:0045739 | inferred from biological aspect of ancestor with PANTHER:PTN000022641 positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | traceable author statement Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from direct assay larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with Abl negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ; GO:2001240 | inferred from biological aspect of ancestor with PANTHER:PTN000022641 optic lobe placode formation ; GO:0001744 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype pole cell migration ; GO:0007280 | traceable author statement male gonad development ; GO:0008584 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype gonad development ; GO:0008406 | non-traceable author statement photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype inferred from genetic interaction with Abl mesoderm development ; GO:0007498 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from physical interaction with so ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype negative regulation of cell fate specification ; GO:0009996 | inferred from mutant phenotype compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype histone dephosphorylation ; GO:0016576 | inferred from biological aspect of ancestor with PANTHER:PTN000022641 response to light stimulus ; GO:0009416 | inferred from mutant phenotype pigment cell development ; GO:0070285 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from genetic interaction with Abl" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG9554, Eya, cli, cli/eya, CLIFT, EY2-1, ey-2, EYA, BcDNA:LD16029, eya, eay, eyes absent, del1, dEYA, CLI, 24582246, Eyes absent" "IPR006545:EYA domain, IPR028472:Eyes absent family, IPR023214:HAD-like domain" CG9554 11-Aug-17 DroID_v2017_08 "Drer\eya4, Drer\eya3, Drer\eya2, Drer\eya1" - Cele\eya-1 "Xtro\eya3, Xtro\eya2, Xtro\eya4, Xtro\eya1" "Mmus\Eya1, Mmus\Eya4, Mmus\Eya2, Mmus\Eya3" "Hsap\EYA4, Hsap\EYA2, Hsap\EYA1, Hsap\EYA3" " larval stage , embryonic stage , adult stage " " eye-antennal disc

, adult head

, morphogenetic furrow | anterior

" " larval stage | third instar , larval stage | second instar , adult stage | male " " eye-antennal disc | gradient

, cyst cell

" "viable,fertile,visible,recessive,female sterile,cold sensitive,partially lethal - majority die,male sterile,female fertile,photoperiod response variant,auditory perception defective,eclosion rhythm defective,neuroanatomy defective,wild-type,lethal,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "gonad,eye,ommatidium,ocellus,germline cell,germarium,spermatid,spermatocyte,primary spermatocyte cyst,posterior vertical bristle,eye-antennal disc,lamina,photoreceptor cell,eye disc,somatic clone,photoreceptor cell & axon,lamina forming neuroblast,subretinal glial cell,presumptive embryonic salivary gland,cell autonomous,retina,denticle belt,cephalopharyngeal skeleton,embryonic/larval neuron,fat body/gonad primordium,somatic mesoderm,visceral mesoderm,embryonic/larval dorsal trunk,embryonic head,visual primordium,Bolwig organ,morphogenetic furrow,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,gonadal sheath proper primordium,male,lateral transverse muscle,dorsal oblique muscle,ventral oblique muscle,ventral acute muscle,embryonic/larval somatic muscle,border follicle cell,supernumerary,polar follicle cell,ectopic,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,embryonic peripheral nervous system & embryonic abdominal segment 9 | lateral,antenno-maxillary complex,embryonic/larval labral segment sense organ,hypophysis,embryonic brain,cell non-autonomous,adult head & adult cuticle | ectopic | somatic clone,orbital bristle,lateral longitudinal muscle 1,precursor,head capsule,scutellar bristle,macrochaeta,wing vein L3,wing,antennal segment & eye | ectopicdpp.blk1,leg & ommatidium | ectopicdpp.blk1,wing & ommatidium | ectopicdpp.blk1,antennal segment,leg,interfollicle cell,egg chamber & basement membrane | apicalupd.PU,antenna,metathoracic leg,wing hinge,head,arista,adult head,antennal disc,embryonic/larval brain | third instar larval stage,dorsal" FBgn0065580 l(2)SH0942 lethal (2) SH0942 http://flybase.org/reports/FBgn0065580 gene - - - "l(2)SH0942, l(2)SH2 0942" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053425 5SrRNA:CR33425 5SrRNA:CR33425 http://flybase.org/reports/FBgn0053425 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33425, 5SrRNA:CR33425" - CR33425 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0010620 CG10939 - http://flybase.org/reports/FBgn0010620 FBgn0034209 protein_coding_gene guanylate cyclase inhibitor activity ; GO:0030251 | inferred from electronic annotation with InterPro:IPR031200 receptor guanylyl cyclase signaling pathway ; GO:0007168 | inferred from electronic annotation with InterPro:IPR031200 ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR031200 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype apical part of cell ; GO:0045177 | inferred from direct assay "CG10939, l(2)06373, Sip1" "IPR001478:PDZ domain, IPR031200:Na(+)/H(+) exchange regulatory cofactor NHERF-4" CG10939 11-Aug-17 DroID_v2017_08 "Drer\slc9a3r1, Drer\slc9a3r1, Drer\LOC100535100, Drer\pdzd3b, Drer\pdzd3a, Drer\pdzk1" - "Cele\lin-7, Cele\nrfl-1" "Xtro\slc9a3r1, Xtro\pdzd3, Xtro\pdzk1, Xtro\slc9a3r2" "Mmus\Pdzk1, Mmus\Slc9a3r1, Mmus\Pdzd3, Mmus\Slc9a3r2" "Hsap\PDZK1, Hsap\PDZD3, Hsap\SLC9A3R2, Hsap\SLC9A3R1" "viable,smell perception defective,lethal,recessive,visible" "follicle cell,somatic clone,filamentous actin | somatic clone,wing vein L3,wing vein,ectopic" FBgn0013254 E(var)3-8 E(var)3-8 http://flybase.org/reports/FBgn0013254 - gene - - - "E-var(3)8, E(var)3-8" - - 11-Aug-17 DroID_v2017_08 - - - - - - "enhancer of variegation,dominant" FBgn0061019 l(3)S025507 lethal (3) S025507 http://flybase.org/reports/FBgn0061019 gene - - - "0255/07, l(3)S025507" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031202 CG13237 - http://flybase.org/reports/FBgn0031202 protein_coding_gene - - - CG13237 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266741 CR45214 - http://flybase.org/reports/FBgn0266741 non_protein_coding_gene - - - CR45214 - CR45214 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0265554 12.19 - http://flybase.org/reports/FBgn0265554 gene - - - 12.19 - - 11-Aug-17 DroID_v2017_08 - - - - - - learning defective FBgn0002654 mat(2)cell-C maternal effect cellularisation defect C http://flybase.org/reports/FBgn0002654 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "cell-PK42, mat(2)cellPK42, mat(2)cell-C" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0035479 CG14983 - http://flybase.org/reports/FBgn0035479 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:25539 zinc ion binding ; GO:0008270 | inferred from sequence model protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:25539 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:25539 CG14983 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG14983 11-Aug-17 DroID_v2017_08 Drer\rfwd3 - Cele\T01G5.7 Xtro\rfwd3 Mmus\Rfwd3 Hsap\RFWD3 viable FBgn0000028 acj6 abnormal chemosensory jump 6 http://flybase.org/reports/FBgn0000028 "FBgn0004418, FBgn0030633" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription corepressor activity ; GO:0003714 | inferred from genetic interaction with vvl inferred from physical interaction with vvl transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" dendrite morphogenesis ; GO:0048813 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with WB:WBGene00006818 "Acj6, ACJ6, CG9151, I-POU, tI-POU, Ipou, acj6" "IPR013847:POU domain, IPR017970:Homeobox, conserved site, IPR000327:POU-specific domain, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR010982:Lambda repressor-like, DNA-binding domain" CG9151 11-Aug-17 DroID_v2017_08 "Drer\pou4f2, Drer\zgc:158291, Drer\pou4f1, Drer\hdx, Drer\pou4f3" "Scer\YOX1, Scer\YHP1" Cele\unc-86 "Xtro\pou4f1, Xtro\pou4f1.2, Xtro\pou4f2, Xtro\pou4f3" "Mmus\Onecut1, Mmus\Pou4f2, Mmus\Hdx, Mmus\Pou4f3, Mmus\Pou4f1" "Hsap\POU4F1, Hsap\POU4F2, Hsap\HDX, Hsap\ONECUT1, Hsap\POU4F3" embryonic stage " ventral nerve cord

, EL neuron

, supraesophageal ganglion

, RP1 neuron

, aCC neuron

, pCC neuron

, embryonic central nervous system

, U neuron

" "viable,fertile,lethal,recessive,smell perception defective,neurophysiology defective,behavior defective,chemosensitive behavior defective,locomotor behavior defective,chemical sensitive,neuroanatomy defective,somatic clone,cell autonomous,male,cell non-autonomous" "adult olfactory receptor neuron Or42a,adult olfactory receptor neuron Or71a,lamina plexus,maxillary palp sense organ,antennal sense organ,lamina monopolar neuron L1,lamina monopolar neuron L3,monopolar laminar cell L1 & synapse,monopolar laminar cell L3 & synapse,antennal glomerulus & neuron | somatic clone,antennal glomerulus VA3 & neuron | somatic clone,antennal glomerulus VM2 & neuron | somatic clone,antennal glomerulus DM6 & neuron | somatic clone,antennal glomerulus DL1 & neuron | somatic clone,antennal glomerulus D & neuron | somatic clone,antennal glomerulus VA1 & neuron | somatic clone,olfactory sensory organ & neuron & dendrite | somatic clone,maxillary palp sensillum basiconicum,antennal lobe glomerulus,male,axon & olfactory neuron & antennal glomerulus DA4 | male | cell autonomous,axon & olfactory neuron & antennal glomerulus DM3 | male | cell autonomous,axon & olfactory neuron & antennal glomerulus VA6 | male | cell autonomous,axon & olfactory neuron & antennal glomerulus VC2 | male | cell non-autonomous,axon & olfactory neuron & antennal glomerulus V | male | cell non-autonomous,axon & olfactory neuron | male | ectopic,axon & olfactory neuron & antennal glomerulus DA4 | somatic clone | cell autonomous,axon & olfactory neuron & antennal glomerulus DM3 | somatic clone | cell autonomous,axon & olfactory neuron & antennal glomerulus VA6 | somatic clone | cell autonomous,axon & olfactory neuron & antennal glomerulus VC2 | somatic clone | cell non-autonomous,axon & olfactory neuron & antennal glomerulus V | somatic clone | cell non-autonomous,axon & olfactory neuron | somatic clone | ectopic,olfactory neuron & maxillary palp sense organ,adult antennal lobe projection neuron DL1 adPN,somatic clone,adult antennal lobe projection neuron D adPN,adult antennal lobe projection neuron VA3 adPN,adult antennal lobe projection neuron VM2 adPN,adult antennal lobe projection neuron DM6 adPN,adult antennal lobe projection neuron VA1v adPN,antennal lobe glomerulus DL1,antennal lobe glomerulus D,antennal lobe glomerulus VA3,antennal lobe glomerulus VM2,antennal lobe glomerulus DM6,antennal lobe glomerulus VA1v,anterior fascicle & motor neuron-537.4,abdominal ventral longitudinal muscle 3 & neuromuscular junction-537.4,abdominal ventral longitudinal muscle 4 & neuromuscular junction-537.4,abdominal ventral longitudinal muscle 1 & neuromuscular junction-537.4,abdominal ventral longitudinal muscle 2 & neuromuscular junction-537.4,neuromuscular junction | ectopic-537.4,bouton,ectopic,motor neuron | embryonic stage,antennal glomerulus & neuronGH146,olfactory sensory organ & neuron & dendriteGH146" FBgn0013725 phyl phyllopod http://flybase.org/reports/FBgn0013725 - protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P21461 binding, bridging ; GO:0060090 | inferred from direct assay protein binding, bridging ; GO:0030674 | inferred from physical interaction with sina, ttk protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P21461 inferred from physical interaction with UniProtKB:Q95RJ9 protein self-association ; GO:0043621 | inferred from physical interaction with phyl" R7 cell fate commitment ; GO:0007465 | inferred from expression pattern inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from direct assay R7 cell fate commitment ; GO:0007465 | inferred from mutant phenotype R7 cell development ; GO:0045467 | traceable author statement sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype Ras protein signal transduction ; GO:0007265 | inferred from genetic interaction with aop inferred from genetic interaction with Raf inferred from genetic interaction with Ras85D inferred from genetic interaction with RasGAP1 R1/R6 cell fate commitment ; GO:0007462 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype proteasomal protein catabolic process ; GO:0010498 | inferred from direct assay regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay R1/R6 cell fate commitment ; GO:0007462 | inferred from expression pattern inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity inferred from direct assay ubiquitin ligase complex ; GO:0000151 | inferred from direct assay "D(DmcycE[JP])2.2, Su(Raf)2C, SR2-3, PHYL, CG10108, phyl, Phyl, phy1" - CG10108 11-Aug-17 DroID_v2017_08 - - - - - Hsap\MAG larval stage " morphogenetic furrow

, eye-antennal disc

" "lethal,recessive,wild-type,visible,dominant,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live,partially,somatic clone,viable" "eye,photoreceptor cell R7,cone cell,precursor,supernumerary,photoreceptor cell R1,photoreceptor cell R6,ommatidium,macrochaeta & scutum,microchaeta & scutum,interommatidial bristle,chordotonal organ & neuron,multidendritic neuron,external sensory organ & neuron,chaeta,somatic clone,eo neuron,thecogen cell,primary pigment cell,mesothoracic tergum & microchaeta,adult abdominal segment 3 & microchaeta,adult abdominal segment 4 & microchaeta,mesothoracic tergum & trichogen cell | supernumerary,mesothoracic tergum & tormogen cell | supernumerary,mesothoracic tergum & chaeta,adult abdominal segment 3 & trichogen cell | supernumerary,adult abdominal segment 3 & tormogen cell | supernumerary,adult abdominal segment 3 & chaeta,adult abdominal segment 4 & trichogen cell | supernumerary,adult abdominal segment 4 & tormogen cell | supernumerary,adult abdominal segment 4 & chaeta,A1-7 lateral longitudinal muscle 1,A1-7 dorsal oblique muscle 4,socket,cephalopharyngeal skeleton,germline clone,filzkorper,A1-7 dorsal transverse muscle 1,A1-7 lateral transverse muscle 4,mesothoracic tergum & microchaeta | ectopicEq1,external sensory organ,ectopic,mesothoracic tergum,scutellar bristle,wing vein L3 & chaeta | ectopicdpp.blk1,sensory neuron,microchaeta,neuron,trichogen cell,tormogen cell" FBgn0005395 gate gate http://flybase.org/reports/FBgn0005395 "FBgn0001093, FBgn0003154" gene - eclosion rhythm ; GO:0008062 | inferred from mutant phenotype - "psi 2, psi-2, psi2, gat, gate" - - 11-Aug-17 DroID_v2017_08 - - - - - - "eclosion rhythm defective,semidominant,locomotor rhythm defective,courtship behavior defective,male,locomotor behavior defective,recessive" FBgn0014052 Su(tor)2-3 Su(tor)2-3 http://flybase.org/reports/FBgn0014052 - gene - - - Su(tor)2-3 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,maternal effect,recessive" FBgn0051146 Nlg1 Neuroligin 1 http://flybase.org/reports/FBgn0051146 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neurexin family protein binding ; GO:0042043 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 integral component of postsynaptic membrane ; GO:0099055 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 trans-synaptic protein complex ; GO:0098820 | inferred from physical interaction with Nrx-1 neuromuscular junction ; GO:0031594 | inferred from direct assay "CG14596, CG12148, anon-WO0118547.256, Nlg1, CG31146, dnlg1, nlg1, DNlg1" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG31146 11-Aug-17 DroID_v2017_08 "Drer\cell, Drer\cel.1, Drer\nlgn1, Drer\nlgn4a, Drer\nlgn2a, Drer\nlgn2b, Drer\nlgn3b, Drer\ces3, Drer\si:ch211-93f2.1, Drer\nlgn4b, Drer\nlgn3a, Drer\ces2" - "Cele\T02B5.3, Cele\Y75B8A.3, Cele\W02B12.4, Cele\ZK994.1, Cele\ZC376.1, Cele\ZC376.3, Cele\nlg-1, Cele\glit-1, Cele\T02B5.1, Cele\ZC376.2" "Xtro\ces3, Xtro\nlgn4x, Xtro\ces2, Xtro\nlgn3, Xtro\nlgn2, Xtro\cel, Xtro\LOC100494782" "Mmus\Ces1b, Mmus\Ces1c, Mmus\Ces3a, Mmus\Ces2a, Mmus\Ces1g, Mmus\Ces1d, Mmus\Ces2e, Mmus\Ces2c, Mmus\Cel, Mmus\Nlgn3, Mmus\Ces2b, Mmus\Ces2f, Mmus\Ces3b, Mmus\Ces2h, Mmus\Ces1e, Mmus\Ces5a, Mmus\Ces2g, Mmus\Ces1h, Mmus\Nlgn2, Mmus\Ces4a, Mmus\Ces1f, Mmus\Nlgn1" "Hsap\CES2, Hsap\CES5A, Hsap\NLGN3, Hsap\CES4A, Hsap\CEL, Hsap\NLGN4X, Hsap\CES3, Hsap\CES1, Hsap\NLGN4Y, Hsap\NLGN2, Hsap\NLGN1" "neuroanatomy defective,neurophysiology defective,viable,fertile" "synapse,bouton,synapseED5223),synapseBG487,neuromuscular junction,neuromuscular junction | larval stage,subsynaptic reticulum,NMJ bouton,NMJ bouton | third instar larval stage,neuromuscular junctionMef2.PR,neuromuscular junction | larval stageMef2.PR,presynaptic cytoskeletal matrix assembled at active zones | third instar larval stage" DRSC12485 I -0.640843946 -2.037697114 -0.009935752 -0.299083309 -0.155071751 -0.854213983 FBgn0046214 vig2 vig2 http://flybase.org/reports/FBgn0046214 protein_coding_gene - regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype histone H3-K9 methylation ; GO:0051567 | inferred from mutant phenotype heterochromatin organization ; GO:0070828 | inferred from mutant phenotype polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "BcDNA:SD06613, anon-WO0118547.290, vig2, CG11844, vig-2" IPR006861:Hyaluronan/mRNA-binding protein CG11844 11-Aug-17 DroID_v2017_08 "Drer\serbp1b, Drer\zgc:103482, Drer\serbp1a" "Scer\STM1, Scer\STF2, Scer\TMA10" Cele\vig-1 "Xtro\serbp1, Xtro\habp4" "Mmus\Habp4, Mmus\Serbp1" "Hsap\SERBP1, Hsap\HABP4" "viable,fertile,suppressor of variegation,dominant,enhancer of variegation,lethal - all die before end of P-stage,some die during P-stage" DRSC30012 IK 3.055946703 -0.003760885 -0.655191502 0.135107198 0.319817587 2.89813172 FBgn0027337 l(1)2Cg lethal (1) 2Cg http://flybase.org/reports/FBgn0027337 - gene - - - l(1)2Cg - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0060405 l(3)S130901 lethal (3) S130901 http://flybase.org/reports/FBgn0060405 gene - - - "1309/01, l(3)S130901" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0032535 Ance-2 Ance-2 http://flybase.org/reports/FBgn0032535 protein_coding_gene peptidyl-dipeptidase activity ; GO:0008241 | inferred from electronic annotation with InterPro:IPR001548 metallopeptidase activity ; GO:0008237 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001548 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001548 "CG16869, CG31844, Ance-2, ance-2" "IPR001548:Peptidase M2, peptidyl-dipeptidase A" CG16869 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-194e6.1, Drer\ace, Drer\ace2" - Cele\acn-1 "Xtro\tmem27, Xtro\ace2, Xtro\ace" "Mmus\Ace, Mmus\Ace2, Mmus\Tmem27, Mmus\Ace3" "Hsap\ACE2, Hsap\TMEM27, Hsap\ACE" viable FBgn0260444 Not10 CCR4-NOT transcription complex subunit 10 http://flybase.org/reports/FBgn0260444 protein_coding_gene - mRNA catabolic process ; GO:0006402 | inferred from direct assay negative regulation of translation ; GO:0017148 | inferred from direct assay CCR4-NOT complex ; GO:0030014 | inferred from direct assay "CG18616, NOT10, dNot10, Not10" IPR011990:Tetratricopeptide-like helical domain CG18616 11-Aug-17 DroID_v2017_08 Drer\cnot10 - - Xtro\cnot10 Mmus\Cnot10 Hsap\CNOT10 "viable,fertile" DRSC14129 K -0.52639716 -0.535237536 -0.752034271 1.03631914 0.238141803 1.746643978 FBgn0261437 CSN8 COP9 signalosome subunit 8 http://flybase.org/reports/FBgn0261437 protein_coding_gene NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype NEDD8-specific protease activity ; GO:0019784 | contributes_to inferred from direct assay COP9 signalosome assembly ; GO:0010387 | inferred from mutant phenotype embryo development ; GO:0009790 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay photoreceptor cell development ; GO:0042461 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs regulation of protein deneddylation ; GO:0060625 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype COP9 signalosome ; GO:0008180 | inferred from direct assay COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity with TAIR:gene:2129434 COP9 signalosome ; GO:0008180 | inferred from mutant phenotype "Csn8, CG13383, CG42522, Dch8, CG33297, CH8, CSN8, csn8, l(2)SH1829, l(2)SH2 1829" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR033464:CSN8/PSMD8/EIF3K" CG42522 11-Aug-17 DroID_v2017_08 Drer\cops8 - - Xtro\cops8 Mmus\Cops8 Hsap\COPS8 "lethal,recessive,immune response defective,developmental rate defective,small body,melanotic mass phenotype,visible,somatic clone,lethal - all die before end of larval stage,some die during third instar larval stage" "melanotic mass,ovary,germline clone,eye,somatic clone,wing,wing vein,ectopic,posterior crossvein,scutellum,mesothoracic tergum,chaeta & mesothoracic tergum | somatic clone" DRSC02257 K 0.040838745 -0.053864819 -0.440448528 0.026810359 1.952280601 1.215695573 FBgn0014387 sov small ovary http://flybase.org/reports/FBgn0014387 FBgn0000898 gene - - - "fs(1)M105, sov" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,male fertile,lethal,recessive" "germline cyst,ovariole,ovary,egg chamber" FBgn0004227 nonA no on or off transient A http://flybase.org/reports/FBgn0004227 "FBgn0000188, FBgn0002957" protein_coding_gene mRNA binding ; GO:0003729 | traceable author statement mRNA binding ; GO:0003729 | inferred from sequence or structural similarity transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from biological aspect of ancestor with PANTHER:PTN000573360 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000573360 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement visual perception ; GO:0007601 | traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000573351 visual perception ; GO:0007601 | inferred from mutant phenotype phototaxis ; GO:0042331 | non-traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | traceable author statement visual behavior ; GO:0007632 | non-traceable author statement" nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "nonA, CG4211, diss, non-A, nonA/diss, NonA, Bj6, Bj6-1, x14, opm2, p54[nrb], NONA" "IPR000504:RNA recognition motif domain, IPR012975:NOPS" CG4211 11-Aug-17 DroID_v2017_08 "Drer\pspc1, Drer\sfpq, Drer\nono" "Scer\NRD1, Scer\PAB1" "Cele\psf-1, Cele\nono-1" "Xtro\nono, Xtro\sfpq" "Mmus\Pspc1, Mmus\Sfpq, Mmus\Nono" "Hsap\SFPQ, Hsap\PSPC1, Hsap\NONO" embryonic stage

ubiquitous " embryonic stage | cellular blastoderm , embryonic stage , adult stage , adult stage && oogenesis stage , larval stage , larval stage | third instar , pupal stage " "

ubiquitous , oocyte | ubiquitous

, follicle cell

, oocyte

, larval salivary gland

, nurse cell

" "viable,fertile,optomotor response defective,courtship behavior defective,male,recessive,song defective,visual behavior defective,behavior defective,neurophysiology defective,wild-type,lethal,partially,flight defective,locomotor behavior defective" DRSC20357 EK 0.806077155 0.297512295 0.532311372 1.915161797 -1.733480479 -1.802325187 FBgn0003444 smo smoothened http://flybase.org/reports/FBgn0003444 - protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from electronic annotation with InterPro:IPR017981 protein binding ; GO:0005515 | inferred from physical interaction with cos transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O16844 G-protein coupled receptor activity ; GO:0004930 | traceable author statement G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity "mucosal immune response ; GO:0002385 | inferred from mutant phenotype Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from genetic interaction with hid eye-antennal disc morphogenesis ; GO:0007455 | inferred from genetic interaction with ptc blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with Dl positive regulation of establishment of protein localization to plasma membrane ; GO:0090004 | inferred from direct assay anterior/posterior lineage restriction, imaginal disc ; GO:0048099 | traceable author statement somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | non-traceable author statement adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ; GO:0007193 | inferred from mutant phenotype eye morphogenesis ; GO:0048592 | inferred from mutant phenotype wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement signal transduction ; GO:0007165 | inferred from sequence or structural similarity ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype" neuronal cell body ; GO:0043025 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | traceable author statement cilium ; GO:0005929 | inferred from direct assay axon ; GO:0030424 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | traceable author statement endosome ; GO:0005768 | traceable author statement dendrite ; GO:0030425 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay "smo, Smo, CG11561, dSmo, SMO" "IPR017981:GPCR, family 2-like, IPR000539:Frizzled protein, IPR015526:Frizzled/secreted frizzled-related protein, IPR020067:Frizzled domain, IPR026544:Smoothened" CG11561 11-Aug-17 DroID_v2017_08 "Drer\fzd2, Drer\sfrp2, Drer\sfrp1b, Drer\sfrp2l, Drer\smo, Drer\fzd9b, Drer\fzd3b, Drer\sfrp1a, Drer\fzd10, Drer\fzd7b, Drer\LOC101884738, Drer\fzd3a, Drer\fzd7a, Drer\szl, Drer\fzd8a, Drer\frzb, Drer\fzd8b, Drer\fzd5, Drer\fzd9a, Drer\corin, Drer\si:cabz01033205.3, Drer\sfrp5" - "Cele\lin-17, Cele\mom-5, Cele\cfz-2" "Xtro\fzd6, Xtro\fzd3, Xtro\fzd4, Xtro\frzb2, Xtro\fzd9, Xtro\fzd8, Xtro\corin, Xtro\fzd2, Xtro\sfrp2, Xtro\szl, Xtro\fzd7, Xtro\smo, Xtro\fzd10, Xtro\sfrp1, Xtro\mfrp, Xtro\frzb, Xtro\col18a1, Xtro\fzd5, Xtro\sfrp5, Xtro\sfrpx" "Mmus\Fzd1, Mmus\Sfrp1, Mmus\Smo, Mmus\Sfrp4, Mmus\Fzd9, Mmus\Corin, Mmus\Fzd10, Mmus\Fzd4, Mmus\Fzd6, Mmus\Fzd2, Mmus\Frzb, Mmus\Mfrp, Mmus\Fzd3, Mmus\Fzd5, Mmus\Sfrp5, Mmus\Fzd7, Mmus\Fzd8, Mmus\Sfrp2" "Hsap\SFRP5, Hsap\MFRP, Hsap\SFRP2, Hsap\FZD2, Hsap\SMO, Hsap\FZD10, Hsap\FZD5, Hsap\FRZB, Hsap\FZD9, Hsap\SFRP4, Hsap\CORIN, Hsap\FZD8, Hsap\FZD3, Hsap\FZD4, Hsap\FZD1, Hsap\FZD7, Hsap\SFRP1, Hsap\FZD6" embryonic stage && larval stage && adult stage "visible,lethal,wild-type,recessive,neuroanatomy defective,size defective,somatic clone,segment polarity phenotype,cold sensitive,mitotic cell cycle defective,cell autonomous,cell non-autonomous,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage" "crossvein,ectopic,wing vein,wing blade,anterior,wing,embryonic/larval tracheal system,embryonic/larval dorsal branch,wing vein L3,wing vein L4,presumptive embryonic/larval peripheral nervous system,longitudinal connective,ventral nerve cord commissure,heart primordium,Bolwig organ,germline clone,embryonic/first instar larval cuticle,denticle,supernumerary,germline cell,cold sensitive,morphogenetic furrow,photoreceptor cell,wing disc,anterior/posterior compartment boundary,follicle stem cell,somatic clone,embryonic epidermis,medial ocellus,ocellus,eye disc,anterior compartment,denticle belt,1st posterior cell,tergite,epiproct,anal plate,female gonopod,abdominal tergite 8,genital arch,clasper,hypandrial bristle,posterior compartment,lamina & neuron | precursor | somatic clone,photoreceptor cell R8,precursor,photoreceptor cell & neuron,ommatidial precursor cluster,adult abdomen & cuticle | anterior compartment,adult abdomen & microchaeta | anterior compartment,eye,adult cuticle,scutellum,microchaeta,photoreceptor cell R8 & eye disc | somatic clone,double row,wing margin,adult head,adult thorax,leg,cell non-autonomous,morphogenetic furrow & nucleus | somatic clone,cell autonomous,third segment of antenna,maxillary palpus,maxillary palp olfactory receptor neuron,wing pouch,head capsule,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,abdominal segment 10,abdominal segment 11,ovariole,germarium region 3,egg chamber,interfollicle cell,proximal,costal cell,submarginal cell,wing vein L1,wing cell,imaginal disc anterior compartment,wing vein L2,wing disc | third instar larval stage,campaniform sensillum of anterior crossvein" FBgn0002781 mod(mdg4) modifier of mdg4 http://flybase.org/reports/FBgn0002781 "FBgn0010160, FBgn0010321, FBgn0010822, FBgn0011326, FBgn0024544, FBgn0038882, FBgn0038883, FBgn0038884, FBgn0038885, FBgn0040578, FBgn0040579, FBgn0040580, FBgn0046992, FBgn0052491, FBgn0063265" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24478 POZ domain binding ; GO:0031208 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay phosphatidate phosphatase activity ; GO:0008195 | inferred from sequence or structural similarity DNA binding ; GO:0003677 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V8P9 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P08970 oogenesis ; GO:0048477 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype male meiosis I ; GO:0007141 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 regulation of chromatin assembly or disassembly ; GO:0001672 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype meiotic chromosome condensation ; GO:0010032 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype inferred from genetic interaction with wun2 polytene chromosome band ; GO:0005704 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleolus ; GO:0005730 | colocalizes_with inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity chromatin ; GO:0000785 | inferred from mutant phenotype condensed nuclear chromosome ; GO:0000794 | colocalizes_with inferred from direct assay "mod(mdg4), CG32491, mod, E(var)3-93D, Mod(mdg4), mod(mdg4)67.2, doom, MOD(MDG4)56.3, pf-2, CG15500, CG7836, Mod(mdg)4, E-(var)3-93D, bpd, Doom, Mod[mdg4], mod(mdg-4), l(3)L3101, E-var(3)1, BcDNA:GH07769, mod2.2, mod(gypsy), l(3)j2B7, l(3)03852, E-var(3)3, E(var)93D, E(var)129, CG7859, CG8076, CG18151, CG15802, CG15501, BcDNA:SD03001, mnm, mod[mdg4], Mod(mdg4)2.2, modMDG4, mnn, Mod(mdg4)-67.2, MOD(MDG4), Mod(mdg4)67.2, mdg4, mod(mdg4)-67.2, mod(mdg4, Enhancer of variegation 93D, modifier mdg4, modifier of mdg4, modifier of midget4, Modifier of mdg4, modifier of mdg4 in meiosis, Modifier67.2, Modifier of mdg4 67.2, branch point disrupted, mmd4, MOD2.2, Mod(mdg 4)67.2, Mod(mdg 4), mod (mdg4), Mod67.2, Mod2.2, LBC, mod-mdg4, mod(mdg)4, R5_3R:17176815..17177103, mod(mdg4)-58.8" "IPR000210:BTB/POZ domain, IPR007588:Zinc finger, FLYWCH-type, IPR011333:SKP1/BTB/POZ domain" CG32491 11-Aug-17 DroID_v2017_08 - Scer\FUS1 "Cele\nhr-45, Cele\edc-3" - Mmus\Aoc1 "Hsap\BACH1, Hsap\BACH2" adult stage organism

"viable,lethal,recessive,polyphasic,female sterile,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,enhancer of variegation,dominant,partially lethal - majority die,cold sensitive,heat sensitive,suppressor of variegation,non-suppressor of variegation,non-enhancer of variegation,meiotic cell cycle defective,male,neuroanatomy defective,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,female fertile,male sterile" "terminal filament,ovary,ovariole,neuromuscular junction | larval stage,neuromuscular junction & abdominal ventral longitudinal muscle 1,neuromuscular junction & abdominal ventral longitudinal muscle 2,neuromuscular junction & abdominal dorsal acute muscle 1,neuromuscular junction & abdominal dorsal acute muscle 2,neuromuscular junction & abdominal dorsal acute muscle 3,neuromuscular junction & abdominal lateral longitudinal muscle 1,neuromuscular junction & abdominal dorsal oblique muscle 4,neuromuscular junction & abdominal dorsal oblique muscle 5,neuromuscular junction & abdominal ventral acute muscle 3,abdominal segment motor neuron,eye,wing,motor neuron | third instar larval stage,wing vein L2,embryo,abdominal ventral longitudinal muscle 3 & neuromuscular junction,neuromuscular junction | ectopic,neuromuscular junction & postsynaptic membrane & larva,meiosis I & nuclear chromosome,G2 phase & nuclear chromosome" FBgn0005677 dac dachshund http://flybase.org/reports/FBgn0005677 - protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VBW6 inferred from physical interaction with UniProtKB:Q9VBW9 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | inferred from biological aspect of ancestor with PANTHER:PTN000971376" "mushroom body development ; GO:0016319 | inferred from mutant phenotype antennal joint development ; GO:0048098 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from expression pattern inferred from mutant phenotype spermathecum morphogenesis ; GO:0035211 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype photoreceptor cell fate specification ; GO:0043704 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement genital disc sexually dimorphic development ; GO:0035263 | inferred from mutant phenotype genital disc morphogenesis ; GO:0007483 | traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype neuron differentiation ; GO:0030182 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype genital disc development ; GO:0035215 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000971376 transcription, DNA-templated ; GO:0006351 | traceable author statement" transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000971376 nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity "CG4952, DAC, Dac, Dm-DAC, dach, BG:DS02780.3, l(2)36Ae, spn, l(2)rK364, dac, Dach, Dac2-3" "IPR003380:Transforming protein Ski, IPR009061:Putative DNA-binding domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG4952 11-Aug-17 DroID_v2017_08 "Drer\dacha, Drer\dachb, Drer\dachd, Drer\dachc" - Cele\dac-1 "Xtro\dach1, Xtro\dach2" "Mmus\Dach2, Mmus\Dach1" "Hsap\DACH2, Hsap\DACH1" " larval stage , embryonic stage | stage 11 , embryonic stage | stage 9-11 , embryonic stage | stage >=9 , larval stage && pupal stage && adult stage , embryonic stage , adult stage | male " " dorsal metathoracic disc

, procephalic neurogenic region && embryonic antennal segment | dorsal & restricted

, photoreceptor cell R7

, protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic ocular segment | dorsal & restricted

, photoreceptor cell R6

, mushroom body

, ventral thoracic disc

, embryonic central nervous system | restricted

, cone cell

, organism

, tritocerebral neuroblast | subset

, eye-antennal disc

, procephalic neurogenic region && embryonic protocerebrum | restricted

, optic lobe

, photoreceptor cell R1

" "lethal,recessive,visible,dominant,somatic clone,neuroanatomy defective" "eye,ommatidium,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,leg,eye-antennal disc,morphogenetic furrow,mushroom body gamma-lobe,adult mushroom body,prothoracic leg & sex comb,sex comb,ectopic,tarsal segment 2,metatarsus,mushroom body alpha-lobe,mushroom body beta-lobe,adult mushroom body beta'-lobe,calyx of adult mushroom body,ellipsoid body,mushroom body spur,prothoracic tibia,prothoracic femur,prothoracic metatarsus,prothoracic tarsal segment 2,prothoracic tarsal segment 3,mesothoracic tibia,mesothoracic femur,mesothoracic metatarsus,mesothoracic tarsal segment 2,mesothoracic tarsal segment 3,metathoracic tibia,metathoracic femur,metathoracic tarsal segment 2,metathoracic tarsal segment 3,ventral thoracic disc,lamina tangential neuron,metathoracic metatarsus,fifth segment of antenna,arista,somatic clone,femur,tibia,tarsal segment,joint,spermathecal duct,clasper,clasper long bristle,clasper tooth,adult mushroom body alpha'-lobe,adult head,wing,bract,antenna,rhabdomeredpp.blk1,interommatidial bristle,anterior/posterior compartment boundary,wing disc,eye | ectopic & adult headGMR.long,eye | ectopic & female genitalia7B" FBgn0004449 Ten-m Tenascin major http://flybase.org/reports/FBgn0004449 "FBgn0010864, FBgn0011500, FBgn0011513, FBgn0011526, FBgn0011680, FBgn0024864, FBgn0037160, FBgn0047332" protein_coding_gene identical protein binding ; GO:0042802 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VYN8 filamin binding ; GO:0031005 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NGK5 inferred from physical interaction with UniProtKB:Q9VYN8 protein heterodimerization activity ; GO:0046982 | inferred from direct assay regulation of homotypic cell-cell adhesion ; GO:0034110 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype maintenance of presynaptic active zone structure ; GO:0048790 | inferred from mutant phenotype presynaptic membrane organization ; GO:0097090 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype synaptic vesicle membrane organization ; GO:0048499 | inferred from mutant phenotype synaptic target attraction ; GO:0016200 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from direct assay positive regulation of locomotion ; GO:0040017 | inferred from mutant phenotype postsynaptic membrane organization ; GO:0001941 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype regulation of homotypic cell-cell adhesion ; GO:0034110 | inferred from direct assay compound eye corneal lens development ; GO:0048058 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype positive regulation of heterotypic cell-cell adhesion ; GO:0034116 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from mutant phenotype neuronal cell body ; GO:0043025 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay postsynaptic membrane ; GO:0045211 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay "Ten-m, Ten-mc, odz/ten-m, ten-m, CT16449, odz, ten(m), 5301, 2017, l(3)05309, ten[m], Ten[m], l(3)00844, odd(Oz), l(3)rP126, l(3)rL201, l(3)rJ307, l(3)05301, Ten79E, CG11452, CG5723, BcDNA:AT25108, Odz, ten-m/odz, Ten-M" "IPR011042:Six-bladed beta-propeller, TolB-like, IPR000742:EGF-like domain, IPR006530:YD repeat, IPR013032:EGF-like, conserved site, IPR008969:Carboxypeptidase-like, regulatory domain, IPR028916:Tox-GHH domain, IPR031325:RHS repeat" CG5723 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-12m10.1, Drer\zgc:153720, Drer\tnc, Drer\si:ch211-166i24.1, Drer\tenm1, Drer\tnr, Drer\tnw, Drer\tenm3, Drer\si:dkey-237h12.3, Drer\tenm4, Drer\si:dkey-34l15.2" - "Cele\F28B4.3, Cele\ten-1, Cele\drd-2" "Xtro\tnxb, Xtro\tenm2, Xtro\tenm4, Xtro\tnc, Xtro\tnn, Xtro\tnr" "Mmus\Tnxb, Mmus\Tnc, Mmus\Tenm4, Mmus\Tenm2, Mmus\Tenm1, Mmus\Tnr, Mmus\Tnn, Mmus\Tenm3" "Hsap\TENM1, Hsap\TENM2, Hsap\TNC, Hsap\TENM3, Hsap\TNN, Hsap\TENM4, Hsap\TNR" " pupal stage , embryonic stage | stage 12-13 , embryonic stage | stage 12 , adult stage , embryonic stage | stage 13 , embryonic stage | stage 5-8 , larval stage--pupal stage , embryonic stage , embryonic stage | 5.5-7.5 hr , larval stage , embryonic stage | 9.5 hr , embryonic stage | 0-12 hr , embryonic stage | stage 10 " " cardioblast

, lymph gland

, supraesophageal ganglion

, imaginal disc

,

segmentally repeated , embryonic central nervous system

, trachea

, ventral nerve cord

, posterior spiracle primordium

" " embryonic stage | 4.5-7.5 hr , embryonic stage | stage 15 , embryonic stage | stage 12-15 , embryonic stage | 5.5-7.5 hr , embryonic stage | stage 8 , embryonic stage | 9.5 hr , embryonic stage | stage 12 , pupal stage , larval stage , embryonic stage | 2.5-3.5 hr , embryonic stage | stage 13 , embryonic stage | stage 16 , embryonic stage | stage 8-9 , embryonic stage | stage 9 , embryonic stage | stage 11 , embryonic stage | stage 11-12 , embryonic stage | stage 6 , embryonic stage | stage 10 , embryonic stage | stage 5 " "

segmentally repeated , visceral mesoderm

, posterior commissure

, mesoderm

segmentally repeated , posterior transverse furrow

, cardioblast

, neuron | restricted

, eye

, embryonic central nervous system | restricted

, neuron

, muscle attachment site

, ventral nerve cord

, posterior midgut proper primordium

, lymph gland | presumptive

, anterior commissure

, mesoderm

, stomodeum

, tracheal system

, longitudinal connective

, procephalic neurogenic region

, anterior transverse furrow

, imaginal disc

" "neuroanatomy defective,somatic clone,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive" "ommatidium,eye photoreceptor cell,interommatidial bristle,supernumerary,intersegmental nerve,intersegmental nerve | embryonic stage,NMJ bouton,somatic clone,lens,photoreceptor cell R7" FBgn0003326 sca scabrous http://flybase.org/reports/FBgn0003326 FBgn0025943 protein_coding_gene signal transducer activity ; GO:0004871 | traceable author statement imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype inferred from genetic interaction with hh regulation of R8 cell spacing in compound eye ; GO:0045468 | traceable author statement R8 cell fate commitment ; GO:0007460 | traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from genetic interaction with N lateral inhibition ; GO:0046331 | non-traceable author statement response to alcohol ; GO:0097305 | inferred from mutant phenotype regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement extracellular region ; GO:0005576 | non-traceable author statement "Sca, sca, mAb sca1, CG17579, Sca1b, clone 38, anon-EST:Liang-38, AAF58455, AAA28880, FBpp0086969, FBpp0086968" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR020837:Fibrinogen, conserved site, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG17579 11-Aug-17 DroID_v2017_08 "Drer\fgb, Drer\angptl2b, Drer\angpt2b, Drer\zmp:0000000846, Drer\tnc, Drer\angptl6, Drer\angpt4, Drer\si:ch1073-110a20.3, Drer\tnr, Drer\si:dkeyp-51b7.3, Drer\si:ch1073-110a20.2, Drer\tnxba, Drer\fga, Drer\fibcd1, Drer\LOC555374, Drer\fgl1, Drer\si:zfos-2330d3.6, Drer\si:ch211-203k16.3, Drer\si:ch211-157b11.8, Drer\si:zfos-2330d3.8, Drer\fgg, Drer\zgc:173915, Drer\angptl5, Drer\angptl2a, Drer\zgc:194887, Drer\si:zfos-2330d3.1, Drer\angpt1, Drer\tnw, Drer\angptl7, Drer\wu:fj11g02, Drer\zgc:171687, Drer\mfap4, Drer\LOC100007488, Drer\angptl4, Drer\fgl2a, Drer\si:ch211-287a12.9, Drer\si:ch1073-110a20.1, Drer\angpt2a, Drer\angptl3, Drer\si:zfos-2330d3.3, Drer\fgl2b, Drer\angptl1a" Scer\SMC1 "Cele\Y69H2.10, Cele\C49C8.5, Cele\C08G9.2, Cele\eea-1, Cele\ZC504.1, Cele\K10D3.4, Cele\T15B7.1, Cele\Y26D4A.12, Cele\ensh-1, Cele\Y69H2.3, Cele\W05B2.2, Cele\Y43C5A.2, Cele\F40A3.2" "Xtro\angptl3, Xtro\angptl2, Xtro\LOC100497330, Xtro\angptl4, Xtro\mfap4, Xtro\angpt4, Xtro\fcn2, Xtro\fgg, Xtro\fgb, Xtro\fcn3, Xtro\fgl2, Xtro\tnxb, Xtro\fga, Xtro\tnc, Xtro\fcn1, Xtro\tnr, Xtro\fibcd1, Xtro\angpt1, Xtro\LOC100488329, Xtro\LOC100491105, Xtro\tnn, Xtro\LOC100488177, Xtro\angptl5, Xtro\fgl1" "Mmus\Tnc, Mmus\Fgg, Mmus\Fga, Mmus\Ankrd26, Mmus\Mfap4, Mmus\Fgl1, Mmus\Angptl2, Mmus\Angpt2, Mmus\Angpt4, Mmus\Fgl2, Mmus\Tnxb, Mmus\Angptl6, Mmus\Fibcd1, Mmus\Fcna, Mmus\Fcnb, Mmus\Angptl7, Mmus\Angpt1, Mmus\Angptl4, Mmus\Tnr, Mmus\Angptl1, Mmus\Fgb, Mmus\Angptl3, Mmus\Tnn" "Hsap\FCN1, Hsap\TNR, Hsap\FGG, Hsap\ANGPTL1, Hsap\TNN, Hsap\ANGPT1, Hsap\FGB, Hsap\ANGPTL2, Hsap\ANGPTL5, Hsap\ANGPT4, Hsap\FCN3, Hsap\ANGPTL7, Hsap\FCN2, Hsap\TNC, Hsap\ANGPTL3, Hsap\FGL2, Hsap\ANGPTL6, Hsap\FIBCD1, Hsap\ANGPT2, Hsap\FGL1, Hsap\MFAP4, Hsap\TNXB, Hsap\ANGPTL4, Hsap\FGA" " embryonic stage | stage 9,10 , embryonic stage , embryonic stage | stage 5 , embryonic stage | stage 5-8 , larval stage | third instar , embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | stage 10-11 , embryonic stage | stage 12 , embryonic stage | stage 10,11 " " neuroblast

, neuron

,

ubiquitous , central nervous system

, ventral neurogenic region

, peripheral nervous system

, optic lobe

, ventral nerve cord

, mechanosensory chaeta

, C1 chordotonal organ precursor cell

, photoreceptor cell R8 | presumptive

, eye-antennal disc

, ventral midline

, sensory mother cell

, sense organ | precursor embryonic thorax

, dorsal mesothoracic disc

, epidermoblast

" " larval stage | third instar , embryonic stage , larval stage " " photoreceptor cell R8

, central nervous system

, imaginal disc

, morphogenetic furrow | anterior to

, eye disc

, epidermis

, peripheral nervous system

, eye disc && morphogenetic furrow | posterior to

, photoreceptor cell R8 | presumptive

, photoreceptor cell R8 | vicinity of

, morphogenetic furrow | restricted

" "partially lethal - majority die,visible,wild-type,smell perception defective,learning defective,lethal,recessive,planar polarity defective,meiotic cell cycle defective,dominant,cell non-autonomous,somatic clone,cell polarity defective,some die during pupal stage" "eye,macrochaeta,adult thorax & macrochaeta,ommatidium,photoreceptor cell R8,eye disc,microchaeta & mesothoracic tergum,supernumerary,eye photoreceptor cell,scutum & macrochaeta,leg & macrochaeta,wing & macrochaeta,dorsocentral bristle,ectopic,scutellar bristle,chemosensory ventral triple row & microchaeta | ectopic,dorsal triple row & microchaeta | ectopic,cell non-autonomous,somatic clone,morphogenetic furrow & filopodium | somatic clone,microchaeta,acrostichal bristle,external sensory organ,tormogen cell,trichogen cell,eo neuron,external sensory organ precursor cell,adult cuticle,adherens junction,septate junction,sensory mother cell,microchaeta & mesothoracic tergum | supernumerary | somatic clone,antennal sense organ,sternopleural bristle,metathoracic coxal sensillum trichodeum,photoreceptor,wing,wing vein,wing margin,distal" FBgn0024846 p38b p38b MAP kinase http://flybase.org/reports/FBgn0024846 "FBgn0014421, FBgn0024951, FBgn0027921" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR003527, InterPro:IPR008352, InterPro:IPR017441 SAP kinase activity ; GO:0016909 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement MAP kinase activity ; GO:0004707 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay MAP kinase activity ; GO:0004707 | inferred from sequence or structural similarity" regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from genetic interaction with Ask1 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype paracrine signaling ; GO:0038001 | inferred from genetic interaction with p38a response to salt stress ; GO:0009651 | inferred from mutant phenotype MAPK cascade ; GO:0000165 | non-traceable author statement defense response to fungus ; GO:0050832 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay regulation of cellular response to oxidative stress ; GO:1900407 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype cellular response to cadmium ion ; GO:0071276 | inferred from direct assay cellular response to reactive oxygen species ; GO:0034614 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cellular response to arsenic-containing substance ; GO:0071243 | inferred from direct assay response to starvation ; GO:0042594 | inferred from mutant phenotype MAPK cascade ; GO:0000165 | inferred from direct assay response to salt stress ; GO:0009651 | inferred from genetic interaction with Atf-2 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from direct assay reactive oxygen species metabolic process ; GO:0072593 | inferred from genetic interaction with p38a positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype inferred from genetic interaction with p38a protein phosphorylation ; GO:0006468 | non-traceable author statement response to heat ; GO:0009408 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from direct assay regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype positive regulation of protein phosphorylation ; GO:0001934 | inferred from genetic interaction with gig regulation of BMP signaling pathway ; GO:0030510 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype response to hydrogen peroxide ; GO:0042542 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:P47811 regulation of innate immune response ; GO:0045088 | inferred from direct assay heart morphogenesis ; GO:0003007 | inferred from genetic interaction with p38a nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 "p38b, p38beta, p38, Dp38, D-p38, D-p38b, p38 beta, p38B, CG7393, p38 MAPK, BG:DS00797.3, 186F5S, anon-sts23, Mpk34C, ESTS:186F5S, Dm p38b, Dmp38b, D-p38 MAPK, dp38b, Dp38b, p38Kb, MAPK, P38" "IPR000719:Protein kinase domain, IPR003527:Mitogen-activated protein (MAP) kinase, conserved site, IPR008352:Mitogen-activated protein (MAP) kinase, p38, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG7393 11-Aug-17 DroID_v2017_08 "Drer\mapk15, Drer\mapk4, Drer\mapk3, Drer\mapk11, Drer\zgc:171775, Drer\mapk12a, Drer\mapk12b, Drer\mapk14a, Drer\mapk1, Drer\mapk14b, Drer\mapk7, Drer\mapk6, Drer\mapk13" "Scer\KSS1, Scer\SLT2, Scer\HOG1, Scer\KDX1, Scer\FUS3, Scer\SMK1" "Cele\pmk-1, Cele\mpk-2, Cele\C05D10.2, Cele\F09C12.2, Cele\pmk-2, Cele\pmk-3, Cele\mpk-1" "Xtro\mapk15, Xtro\mapk6, Xtro\mapk7, Xtro\mapk1, Xtro\LOC100145045, Xtro\mapk14, Xtro\mapk12, Xtro\mapk4, Xtro\mapk11" "Mmus\Mapk7, Mmus\Mapk11, Mmus\Mapk3, Mmus\Mapk15, Mmus\Mapk12, Mmus\Mapk4, Mmus\Mapk14, Mmus\Mapk13, Mmus\Mapk6, Mmus\Mapk1" "Hsap\MAPK7, Hsap\MAPK12, Hsap\MAPK1, Hsap\MAPK14, Hsap\MAPK11, Hsap\MAPK15, Hsap\MAPK6, Hsap\MAPK13, Hsap\MAPK3, Hsap\MAPK4" embryonic stage " anterior embryonic/larval midgut

,

ubiquitous , posterior embryonic/larval midgut

" "neuroanatomy defective,immune response defective,developmental rate defective,melanotic mass phenotype,drug conditional,partially lethal - majority die,recessive,starvation stress response defective,heat stress response defective,osmotic stress response defective,small body,decreased cell size,nutrition conditional,visible,oxidative stress response defective,long lived,viable,short lived,locomotor behavior defective,RU486 conditional" "NMJ bouton,embryonic/larval hindgut,drug conditional,posterior,nutrition conditional,wing vein,ectopic,wing,NMJ bouton | larval stage,adult heart,RU486 conditional" FBgn0003310 S Star http://flybase.org/reports/FBgn0003310 "FBgn0010102, FBgn0010674, FBgn0069199" protein_coding_gene - "behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype epithelial cell proliferation involved in Malpighian tubule morphogenesis ; GO:0061331 | inferred from mutant phenotype stomatogastric nervous system development ; GO:0007421 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement epidermal growth factor receptor ligand maturation ; GO:0038004 | inferred from genetic interaction with spi protein targeting to Golgi ; GO:0000042 | traceable author statement protein targeting to Golgi ; GO:0000042 | inferred from genetic interaction with spi stem cell fate commitment ; GO:0048865 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from genetic interaction with rho, spi branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from genetic interaction with Sos, sev epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype" Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay membrane ; GO:0016020 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence model perinuclear endoplasmic reticulum ; GO:0097038 | inferred from direct assay "S, star, CG4385, EK2-2, l(2)07056, l(2)05671, EY2-4, ES2-4, Star/asteroid, fltr, l(2)c00080, l(2)rK134, l(2)k09538, l(2)21Eb, E(Raf)2B, EC2-2, Star" - CG4385 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , larval stage | third instar " " midline glial cell

, mesectoderm

, eye-antennal disc

, photoreceptor cell R5 | presumptive

, morphogenetic furrow

, photoreceptor cell R2 | presumptive

, photoreceptor cell R8 | presumptive

, embryonic optic lobe primordium

" "lethal,recessive,visible,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,chemical sensitive,cell polarity defective,female fertile,maternal effect,germline clone,female sterile,decreased cell number,viable,female sterile soma-dependent,increased cell death,neuroanatomy defective,wild-type" "presumptive embryonic/larval central nervous system,denticle belt,eye,photoreceptor cell R2,photoreceptor cell R5,photoreceptor cell R8,wing vein L2,wing vein L3,wing vein L4,wing vein L5,ommatidium,photoreceptor,mesothoracic tibial bract,mesothoracic tarsal segment 1 & bract,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,fascicle,wing,eye photoreceptor cell,somatic clone,midline glial cell,dorsal neurohemal organ,wing vein,germline clone,macrochaeta,embryonic/first instar larval cuticle,maternal effect,interommatidial bristle,ovariole,dorsal appendage,photoreceptor cell R7,longitudinal connective,VUM interneuron 1,VUM interneuron 2,VUM interneuron 3,MP1 neuron,anterior commissure,posterior commissure,ventral,Keilin's organ,lamellocyte,conditional,VUM neuron,embryonic ventral nervous system,anal pad,cephalopharyngeal skeleton,larval sense organ & antennal segment,larval sense organ & maxillary segment,commissure,sensory neuron,motor neuron,egg chamber,dorsocentral bristle,scutellar bristle,nurse cell,oocyte,photoreceptor cell,inter-ommatidial precursor cell,embryonic/larval stomatogastric nervous system,stomodeal invagination,embryonic ventral epidermis,genital disc primordium,embryonic/larval somatic muscle,ventral nerve cord,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,midline ventral glial cell,embryonic/larval dorsal trunk,embryonic/larval trachea,lch5 neuron,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell,optic cartridge,wing margin,ectopic" FBgn0026598 Apc2 Adenomatous polyposis coli 2 http://flybase.org/reports/FBgn0026598 - protein_coding_gene "beta-catenin binding ; GO:0008013 | inferred from electronic annotation with InterPro:IPR009240, InterPro:IPR026818 protein binding ; GO:0005515 | inferred from physical interaction with arm protein binding ; GO:0005515 | inferred from physical interaction with arm inferred from physical interaction with dia inferred from physical interaction with Kap3 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity" "positive regulation of protein catabolic process ; GO:0045732 | inferred from genetic interaction with Apc establishment of mitotic spindle localization ; GO:0040001 | traceable author statement cell adhesion ; GO:0007155 | inferred from mutant phenotype pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from genetic interaction with Apc cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement microtubule-based process ; GO:0007017 | traceable author statement establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from mutant phenotype cell adhesion ; GO:0007155 | non-traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from genetic interaction with Apc imaginal disc pattern formation ; GO:0007447 | inferred from genetic interaction with Apc microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype inferred from genetic interaction with Apc syncytial nuclear migration ; GO:0035190 | inferred from mutant phenotype medulla oblongata development ; GO:0021550 | inferred from genetic interaction with Apc negative regulation of signal transduction ; GO:0009968 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from direct assay negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with wg chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype inferred from genetic interaction with Apc neuroblast proliferation ; GO:0007405 | inferred from genetic interaction with Apc brain development ; GO:0007420 | inferred from genetic interaction with Apc head involution ; GO:0008258 | inferred from genetic interaction with Apc positive regulation of proteolysis ; GO:0045862 | traceable author statement axon guidance ; GO:0007411 | inferred from genetic interaction with Apc Wnt signaling pathway ; GO:0016055 | traceable author statement negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with Apc regulation of Wnt signaling pathway ; GO:0030111 | inferred from genetic interaction with Apc" protein complex ; GO:0043234 | inferred from physical interaction with dia dendrite ; GO:0030425 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay adherens junction ; GO:0005912 | traceable author statement apical cortex ; GO:0045179 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay basal cortex ; GO:0045180 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity nucleus ; GO:0005634 | traceable author statement cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement beta-catenin destruction complex ; GO:0030877 | inferred by curator from GO:0045732 inferred from physical interaction with Axn actin filament ; GO:0005884 | colocalizes_with inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay spindle pole ; GO:0000922 | inferred from direct assay "APC2, dAPC2, E-APC dAPC2, apc2, E-APC, APC, dAPC2/E-APC, dApc2, CG6193, D-APC2, d-APC2, Apc2, Dm APC2, e-apc, dapc2" "IPR000225:Armadillo, IPR009223:Adenomatous polyposis coli protein repeat, IPR009240:Adenomatous polyposis coli protein, 15 residue repeat, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR026818:Adenomatous polyposis coli (APC) family" CG6193 11-Aug-17 DroID_v2017_08 "Drer\apc, Drer\apc2" - Cele\apr-1 "Xtro\apc, Xtro\apc2" "Mmus\Apc2, Mmus\Apc" "Hsap\APC2, Hsap\APC" "wild-type,viable,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage,germline clone,partially lethal - majority live,lethal,recessive,heat sensitive,maternal effect,sterile,visible,non-rescuable maternal effect" "denticle,supernumerary,denticle belt,embryonic/first instar larval cuticle,embryonic/larval cuticle,maternal effect,hub cell,male germline stem cell,nucleus | embryonic stage 4 | germline clone,actin filament | embryonic stage 4 | germline clone,cortical actin cytoskeleton & syncytial blastoderm embryo | maternal effect,spindle & syncytial blastoderm embryo | maternal effect,organism | embryonic stage 4,cortical actin cytoskeleton,epithelial cell,syncytial blastoderm embryo,germline clone,spindle | embryonic stage 4 | germline clone,egg chamber,oocyte,abdominal ventral acute muscle 1 founder cell,abdominal ventral acute muscle 2 founder cell,abdominal ventral acute muscle 3 founder cell,heat sensitive,dorsal fine hair,male germline stem cell & spindle,male germline stem cell & centrosome,abdominal ventral transverse muscle 1 founder cell,abdominal lateral oblique muscle 1 founder cell,wing vein,ommatidium,chaeta,nurse cell,nurse cell & plasma membrane,spot adherens junction,plasma membrane,embryonic epidermis,midgut constriction 1" FBgn0003270 amos absent MD neurons and olfactory sensilla http://flybase.org/reports/FBgn0003270 "FBgn0003689, FBgn0027104" protein_coding_gene RNA polymerase II regulatory region DNA binding ; GO:0001012 | contributes_to inferred from physical interaction with da protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR032664 sensory organ precursor cell fate determination ; GO:0016360 | inferred from direct assay sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | traceable author statement sensory organ development ; GO:0007423 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype sensory organ development ; GO:0007423 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" - "Amos, asolo, Tft, Roi, rolo, CG10393, amos, bHLHa10" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR032664:Protein atonal/amos/lin-32" CG10393 11-Aug-17 DroID_v2017_08 "Drer\atoh1c, Drer\neurod6b, Drer\neurod1, Drer\neurod6a, Drer\atoh1b, Drer\atoh7, Drer\neurod4, Drer\atoh1a" - "Cele\lin-32, Cele\cnd-1" "Xtro\atoh1, Xtro\atoh7, Xtro\neurod6, Xtro\neurod4" "Mmus\Neurod4, Mmus\Atoh7, Mmus\Twist2, Mmus\Neurod1, Mmus\Neurod6, Mmus\Atoh1" "Hsap\NEUROD6, Hsap\ATOH7, Hsap\ATOH1, Hsap\NEUROD4, Hsap\TWIST2, Hsap\NEUROD1" " embryonic stage , adult stage && oogenesis stage , pupal stage , pupal stage | 0-4 hr , embryonic stage | stage 10 , embryonic stage | stage 5 , embryonic stage | blastoderm " " embryonic labial segment | restricted

, abdominal segment | restricted

, centripetally migrating follicle cell

, antennal disc

, tarsus | anlagen

, olfactory sensory organ | anlagen

, antenno-maxillary complex | anlagen

, embryonic labial segment

, nurse cell

, oocyte

, thoracic segment | restricted

, antenno-maxillary complex | restricted

, embryonic antennal segment

,

, embryonic mandibular segment

, sensory mother cell

,

ubiquitous , embryonic antennal segment | restricted

" "viable,visible,lethal,recessive,dominant,neuroanatomy defective,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage" "eye,dorsal abdominal cluster,dorsal multidendritic neuron,abdominal dorsal bipolar neuron dbp,ommatidium,eye disc,rhabdomere,cone cell,eye photoreceptor cell,supernumerary,pigment cell,somatic clone,rhabdomere R7,rhabdomere R8,mesothoracic metatarsus,mesothoracic tarsal bristle,chaeta,ectopic,tormogen cell,adult mesothoracic segment,metathoracic laterotergite,scutellum,sensory mother cell,wing disc,macrochaeta,antennal sense organ,microchaeta,mesothoracic tergum,postalar bristle,dorsocentral bristle,scutellar bristle,sensory neuron,dorsal,sensillum basiconicum & antenna,sensillum trichodeum of antennal segment 3,macrochaeta | ectopic & antenna,sensory mother cell & antennal disc,embryonic antennal sense organ,olfactory neuron & embryonic antennal sense organ,sensillum basiconicum & antennaM36F-S6),macrochaeta | ectopic & antennaM36F-S6),olfactory receptor neuron,antenna,sensillum basiconicum of antennal segment 3,sensillum coeloconicum of antennal segment 3,sense organ,scutellum & chordotonal organ | ectopic-109-68,wing vein L3 & chordotonal organ | ectopic-109-68,wing vein L3 & external sensory organ | ectopic-109-68,adult thorax & olfactory sensory organ | ectopic-109-68,adult head & olfactory sensory organ | ectopic-109-68,wing vein L3 & olfactory sensory organ | ectopic-109-68,microchaeta & adult thorax-109-68,adult thorax & macrochaeta-109-68,antennal segment 1 & olfactory sensory organ | ectopichs.PB,antennal segment 2 & olfactory sensory organ | ectopichs.PB,sensillum campaniformium,mechanosensory chaeta,sensory mother cell | ectopic & dorsal mesothoracic discdpp.blk1,macrochaeta | ectopic & adult headC-765,macrochaeta | ectopic & mesothoracic tergumC-765,sensillum campaniformium | ectopic & wingC-765,wing sensillum,multidendritic neuron,scolopidial neuron,ventral multidendritic neuron,embryonic/larval neuron,dorsal multidendritic neuron ddaC" FBgn0015805 HDAC1 Histone deacetylase 1 http://flybase.org/reports/FBgn0015805 "FBgn0003632, FBgn0003634, FBgn0010843, FBgn0016893" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with mip120 transcription corepressor activity ; GO:0003714 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24459 histone deacetylase activity ; GO:0004407 | non-traceable author statement histone deacetylase activity ; GO:0004407 | inferred from direct assay transcription corepressor activity ; GO:0003714 | inferred from physical interaction with kay histone deacetylase activity ; GO:0004407 | inferred from sequence or structural similarity with HGNC:4852 inferred from sequence or structural similarity with SGD:S000005274 protein binding ; GO:0005515 | inferred from physical interaction with Smyd4-2 histone deacetylase activity ; GO:0004407 | inferred from mutant phenotype "gene silencing ; GO:0016458 | inferred from mutant phenotype negative regulation of axonogenesis ; GO:0050771 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay histone deacetylation ; GO:0016575 | inferred from mutant phenotype tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay dendrite guidance ; GO:0070983 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay chromatin silencing ; GO:0006342 | inferred from physical interaction with esc inferred from physical interaction with E(z) histone deacetylation ; GO:0016575 | non-traceable author statement regulation of histone acetylation ; GO:0035065 | inferred from mutant phenotype respiratory electron transport chain ; GO:0022904 | inferred from direct assay determination of adult lifespan ; GO:0008340 | traceable author statement negative regulation of response to gamma radiation ; GO:2001229 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement chromatin silencing ; GO:0006342 | inferred from genetic interaction with Pc inferred from physical interaction with Pc negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from expression pattern blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with ttk chromosome condensation ; GO:0030261 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype inferred from genetic interaction with HDAC3 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype inferred from physical interaction with ci" ESC/E(Z) complex ; GO:0035098 | traceable author statement NuRD complex ; GO:0016581 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay Myb complex ; GO:0031523 | inferred from direct assay ESC/E(Z) complex ; GO:0035098 | inferred from direct assay transcriptional repressor complex ; GO:0017053 | inferred from physical interaction with Su(var)3-3 inferred from physical interaction with CoRest polytene chromosome interband ; GO:0005705 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay Sin3 complex ; GO:0016580 | non-traceable author statement polytene chromosome ; GO:0005700 | inferred from direct assay NuRD complex ; GO:0016581 | inferred from physical interaction with Mi-2 Sin3-type complex ; GO:0070822 | inferred from direct assay "dRPD3, RPD3, DRpd3, rpd3, HDAC1, l(3)04556, Hdac1, CG7471, rpd[3], dmHDA401, Rpd3/HDAC, HDAC, dRpd3, dHDAC1, HDAC-1, dHDAC-1, DmHDAC1, E(var)3-64BC, l(3)64Cc, Su(var)326, Su(var)328, Rpd3, Su(var)3-26, DHDAC1, drpd3, hdac1, Hdac" "IPR000286:Histone deacetylase superfamily, IPR003084:Histone deacetylase, IPR023801:Histone deacetylase domain" CG7471 11-Aug-17 DroID_v2017_08 "Drer\hdac1, Drer\hdac3, Drer\phka1a" "Scer\HOS2, Scer\HOS1, Scer\RPD3" "Cele\hda-1, Cele\hda-3, Cele\hda-2" "Xtro\hdac8, Xtro\hdac2, Xtro\hdac1, Xtro\hdac3" "Mmus\Hdac2, Mmus\Hdac8, Mmus\Hdac1, Mmus\Hdac3" "Hsap\HDAC1, Hsap\HDAC3, Hsap\HDAC8, Hsap\HDAC2" " larval stage , embryonic stage&&larval stage&&adult stage " eye-antennal disc

"lethal,suppressor of variegation,recessive,polyphasic,maternal effect,poor,partially lethal - majority die,visible,drug conditional,long lived,dominant,male,female,pair rule phenotype,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,enhancer of variegation,viable,fertile,neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell number,mitotic cell cycle defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,increased cell death" "cuticle,maternal effect,wing,macrochaeta,alula,sex comb,drug conditional,cephalopharyngeal skeleton,germline clone,denticle belt,embryonic epidermis,embryonic segment,embryo,segment,ommatidium,adult antennal lobe projection neuron DL1 adPN,somatic clone,wing disc,projection neuron,mesothoracic tergum,ganglion mother cell" DRSC08696 K 0.252249731 -1.023636735 -1.235260356 -0.33432081 0.92010934 2.721467973 FBgn0011217 eff effete http://flybase.org/reports/FBgn0011217 "FBgn0004831, FBgn0011011, FBgn0011333, FBgn0011657, FBgn0013661, FBgn0013663, FBgn0013935, FBgn0062081" protein_coding_gene "ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Diap1 ubiquitin conjugating enzyme activity ; GO:0061631 | inferred from direct assay ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay ubiquitin conjugating enzyme activity ; GO:0061631 | inferred from genetic interaction with SGD:S000000286,SGD:S000002466 protein binding ; GO:0005515 | inferred from physical interaction with sina" "protein polyubiquitination ; GO:0000209 | inferred from direct assay protein polyubiquitination ; GO:0000209 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of R7 cell differentiation ; GO:0045676 | inferred from genetic interaction with sina compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000000286 inferred from sequence or structural similarity with SGD:S000002466 anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from genetic interaction with SGD:S000000286,SGD:S000002466 spermatid development ; GO:0007286 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype protein linear polyubiquitination ; GO:0097039 | inferred from direct assay regulation of protein stability ; GO:0031647 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype" microtubule associated complex ; GO:0005875 | inferred from direct assay "UbcD1, UBCD1, ubcD1, CG7425, UbcD, UBCD-1, E(Pc)88D, ms(3)ry3, ms(3)ry1, 6535, 3527, SS3-3, Ubc-D1, fs(3)01295, UBC4, ms(3)88D, ms(3)neo2, ms(3)3, ms(3)1, ms(3)01295, mei68, l(3)s1782, l(3)j2C8, l(3)01462, anon-WO0118547.343, eff, effete, Eff, EFF, UbcH5" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG7425 11-Aug-17 DroID_v2017_08 "Drer\ube2d4, Drer\ube2e2, Drer\ube2d1a, Drer\ube2t, Drer\ube2nb, Drer\ube2d2l, Drer\ube2na, Drer\ube2e1, Drer\ube2d2, Drer\ube2e3, Drer\ube2d1b, Drer\ube2d3" "Scer\UBC5, Scer\UBC13, Scer\UBC4, Scer\PEX4" "Cele\F52C6.12, Cele\ubc-22, Cele\let-70, Cele\ubc-24" "Xtro\ube2d1, Xtro\ube2n, Xtro\ube2d3, Xtro\ube2e2, Xtro\ube2d4, Xtro\ube2e1, Xtro\ube2e3" "Mmus\Ube2dnl1, Mmus\Ube2e2, Mmus\Ube2d2b, Mmus\Ube2e3, Mmus\Ube2n, Mmus\Ube2t, Mmus\Ube2d2a, Mmus\Ube2e1, Mmus\Ube2dnl2, Mmus\Ube2d1, Mmus\Ube2d3" "Hsap\UBE2E1, Hsap\UBE2N, Hsap\UBE2E3, Hsap\UBE2D1, Hsap\UBE2D3, Hsap\UBE2D2, Hsap\UBE2D4, Hsap\UBE2E2, Hsap\UBE2NL, Hsap\UBE2T" " embryonic stage | early , embryonic stage -- adult stage , adult stage | male " "lethal,viable,fertile,male sterile,recessive,female sterile,female fertile,mitotic cell cycle defective,neuroanatomy defective,somatic clone,partially lethal - majority die,meiotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,poor,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,dominant" "testis,female germline stem cell,egg chamber & cell,egg chamber & mitotic cell cycle,nurse cell fusome,mitosis & chromosome, telomeric region,nurse cell & nucleus,neuroblast,somatic clone,germarium,germline clone,macrochaeta,meiosis & chromosome, telomeric region | male,meiosis & nuclear chromosome | male,dendrite,neuron,ectopic,nuclear chromosome,eye,eye photoreceptor cell,pigment cell,sex comb,mesothoracic leg,dorsal multidendritic neuron ddaC,ganglion mother cell" FBgn0000341 Coa Coarse http://flybase.org/reports/FBgn0000341 - gene - - - Coa - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing & macrochaeta FBgn0001180 hb hunchback http://flybase.org/reports/FBgn0001180 FBgn0015224 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "regulation of development, heterochronic ; GO:0040034 | inferred from electronic annotation with InterPro:IPR027742 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay terminal region determination ; GO:0007362 | inferred from genetic interaction with tor generation of neurons ; GO:0048699 | inferred from mutant phenotype regulation of transcription involved in anterior/posterior axis specification ; GO:0044324 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from expression pattern posterior head segmentation ; GO:0035289 | traceable author statement open tracheal system development ; GO:0007424 | traceable author statement zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | non-traceable author statement ventral cord development ; GO:0007419 | non-traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement anterior region determination ; GO:0007355 | non-traceable author statement trunk segmentation ; GO:0035290 | traceable author statement salivary gland development ; GO:0007431 | traceable author statement regulation of development, heterochronic ; GO:0040034 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype morphogenesis of a branching structure ; GO:0001763 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement neuroblast fate determination ; GO:0007400 | inferred from expression pattern inferred from mutant phenotype ganglion mother cell fate determination ; GO:0007402 | traceable author statement torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 "hb, Hb, Rg-pbx, hbHLH, Rg-bx, l(3)85Ah, R-pbx, CG9786, Hunchback, HB" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR027742:Protein hunchback, IPR027775:C2H2- zinc finger protein family subset, IPR013087:Zinc finger C2H2-type" CG9786 11-Aug-17 DroID_v2017_08 "Drer\znf827, Drer\rest, Drer\LOC568955, Drer\znf513" Scer\RPN4 Cele\hbl-1 "Xtro\ikzf5, Xtro\znf827, Xtro\rest, Xtro\ikzf2" "Mmus\Zfp513, Mmus\Rest, Mmus\Ikzf5, Mmus\Zfp827" "Hsap\IKZF4, Hsap\ZNF827, Hsap\ZNF513, Hsap\REST, Hsap\IKZF5, Hsap\ZNF80" " embryonic stage | embryonic cycle 13 , embryonic stage | stage 4 , embryonic stage | early , embryonic stage | 2-6hr , embryonic stage | embryonic cycle 14 , adult stage | female , embryonic stage | stage >8 , adult stage && oogenesis stage | stage S7-11 , embryonic stage | 0-8hr , embryonic stage | embryonic cycle 11-13 " " organism | 0-30% egg length

,

anterior ,

50-100% egg length , organism | 10-30% egg length

, embryonic central nervous system

,

0-10% egg length , nurse cell

,

posterior , organism | 50-100% egg length

,

0-20% egg length , organism | 0-20% egg length

, organism | 50-90% egg length

" " embryonic stage | early , embryonic stage | stage 9-11 , embryonic stage , embryonic stage | stage 15-17 , embryonic stage | stage 4 , oogenesis stage " "

~30-100% egg length{ + pum13 } , tritocerebral neuroblast | subset

, neuroblast

{ $ l(1)sc- } ,

~30-100% egg length{ + pumMsc } , deuterocerebral neuroblast | subset

, EW1 neuron

,

anterior ,

, neuroblast

, protocerebral neuroblast | subset

, organism | 50-100% egg length ,

0-20% egg length ,

~70-100% egg length{ + pum1 } ,

posterior ,

anterior{ + osk*, nosbcd.3UTR } , GW neuron

, ubiquitous

{ + pumFC8 } " "embryonic/larval segmentation phenotype,viable,fertile,neuroanatomy defective,heat sensitive,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,maternal effect,dominant,lethal,female,lethal - all die before end of larval stage,some die during larval stage,homeotic,pair rule phenotype,visible,some die during pupal stage" "embryonic head,embryonic thoracic segment,embryonic abdominal segment,U neuron,supernumerary,U5 neuron,U3 neuron,U1 neuron,U2 neuron,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic mesothoracic segment,abdomen,ectopic,heat sensitive,pole cell,embryonic metathoracic segment,embryonic epidermis,embryonic prothoracic segment,maternal effect,EW2 neuron,EW1 neuron,ganglion mother cell GMC1-1a,aCC neuron,RP2 motor neuron,motor neuron,medial-most cell body glial cell,abdominal segment,filzkorper,parasegment 6,parasegment 13,embryonic abdominal segment 4,embryonic abdominal segment 2,posterior,cephalopharyngeal skeleton,embryo,embryonic gnathal segment,haltere,metathoracic segment,adult metathoracic segment,embryonic/larval dorsal trunk,embryonic labial segment,mouth hooks,larval labial segment,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,larval abdominal segment 7,larval abdominal segment 8,thorax,prothoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 3,central nervous system,brain,gnathal segment,abdominal segment 8,adult salivary gland primordium,neuroblast NB7-3,GW neuron,neuroblast NB7-1,fpCC neuron,pCC neuron,embryonic/first instar larval cuticle,embryonic abdomen,anterior,abdominal 8 ventral denticle belt,mesothoracic segment,abdominal segment 1,hypostomal sclerite,embryonic/larval labial segment sensillum,larval head,extended germ band embryo,longitudinal connective,commissure,embryonic neuroblast,ectopic | embryonic stage,embryonic/larval esophagus | embryonic stage,median tooth,epipharyngeal sclerite,dorsal bridge,embryonic/larval pharynx | embryonic stage,gastric caecum,embryonic/larval proventriculus | embryonic stage,precursor cell of the stomatogastric nervous system,dorsal arm of pharyngeal sclerite,ventral arm of pharyngeal sclerite,U4 neuron,FMRFamide SE2 neuron,eye,antennal lobe neuroblast,somatic clone" DRSC16963 K -0.647216458 -0.26055423 0.986051002 0.308954246 0.135749835 1.638106134 FBgn0051947 CG31947 - http://flybase.org/reports/FBgn0051947 protein_coding_gene - - - CG31947 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000432 dep depressed http://flybase.org/reports/FBgn0000432 - gene - - - dep - - 11-Aug-17 DroID_v2017_08 - - - - - - visible wing FBgn0051205 CG31205 - http://flybase.org/reports/FBgn0051205 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG31205 "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR001314:Peptidase S1A, chymotrypsin family" CG31205 11-Aug-17 DroID_v2017_08 - - - - Mmus\Tmprss9 "Hsap\PAMR1, Hsap\TMPRSS9, Hsap\PRSS48" "viable,fertile" FBgn0061138 l(3)S000627c lethal (3) S000627c http://flybase.org/reports/FBgn0061138 gene - - - "0006/27, l(3)S000627c" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0040805 CG12355 - http://flybase.org/reports/FBgn0040805 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:26827 CG12355 IPR007248:Mpv17/PMP22 CG12355 11-Aug-17 DroID_v2017_08 "Drer\pxmp2, Drer\mpv17l2, Drer\si:dkeyp-72e1.7, Drer\nat9, Drer\si:ch211-120k19.1, Drer\mpv17" "Scer\SYM1, Scer\YOR292C" Cele\Y67D2.5 "Xtro\pxmp2, Xtro\mpv17l, Xtro\mpv17l2" "Mmus\Pxmp2, Mmus\Mpv17l2, Mmus\Mpv17, Mmus\Mpv17l" "Hsap\PXMP2, Hsap\MPV17L2, Hsap\NAT9, Hsap\MPV17, Hsap\MPV17L" viable FBgn0003028 ovo ovo http://flybase.org/reports/FBgn0003028 "FBgn0000825, FBgn0000849, FBgn0003650, FBgn0029741" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 DNA binding ; GO:0003677 | traceable author statement DNA binding ; GO:0003677 | inferred from direct assay" "epidermal cell differentiation ; GO:0009913 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype germ-line sex determination ; GO:0018992 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:P19339 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from mutant phenotype female germ-line sex determination ; GO:0019099 | non-traceable author statement positive regulation of transposon integration ; GO:0070896 | inferred from mutant phenotype non-sensory hair organization ; GO:0035316 | traceable author statement oogenesis ; GO:0048477 | traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cuticle development ; GO:0042335 | traceable author statement non-sensory hair organization ; GO:0035316 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement adult feeding behavior ; GO:0008343 | inferred from mutant phenotype cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0003677 "svb, CG15467, ovo/svb, Ovo-D, ovo/shavenbaby, OVO, CG6824, Svb, fs(1)K1237, Ovo, Fs(1)K1103, fs(1)M38, fs(1)M1, Fs(1)K155, Fs(1)K1237, ovo, Svb/Ovo, ovoD, Shv" "IPR011989:Armadillo-like helical, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR027775:C2H2- zinc finger protein family subset, IPR013087:Zinc finger C2H2-type, IPR027755:Transcription factor Ovo-like" CG6824 11-Aug-17 DroID_v2017_08 "Drer\zbtb18, Drer\znf131, Drer\ovol1, Drer\zgc:171929, Drer\hic1l, Drer\hic2, Drer\hic1, Drer\si:dkey-17e16.13" "Scer\RPN4, Scer\MET31" "Cele\lin-48, Cele\ztf-2, Cele\Y5F2A.4" "Xtro\ovol1, Xtro\ovol2" "Mmus\Rest, Mmus\Zfp770, Mmus\Zfp131, Mmus\Ovol1, Mmus\Ovol2, Mmus\Ovol3" "Hsap\OVOL3, Hsap\ZNF770, Hsap\OVOL2, Hsap\ZNF131, Hsap\REST, Hsap\OVOL1" " oogenesis stage | stage S8 , embryonic stage | cellular blastoderm , embryonic stage | stage 14 , embryonic stage | stage 10-11 , embryonic stage | stage 13 , embryonic stage | stage 10 , embryonic stage | stage 17 , embryonic stage | mid , embryonic stage | stage 8 , embryonic stage | stage 1-2 , embryonic stage | stage 12 , embryonic stage | stage 6 , egg stage | unfertilized egg , oogenesis stage , embryonic stage | syncytial blastoderm , adult stage && oogenesis stage | stage S10 , embryonic stage | early , oogenesis stage | stage S10 && adult stage | female , adult stage && oogenesis stage , embryonic stage | stage 5-8 " " organism

,

ubiquitous , dorsal hair

, embryonic labial segment

, denticle belt | segmentally repeated

, antenna

, gonad

, denticle belt | restricted

, cephalic furrow | restricted

, intercalary segment

, organism | 60-80% egg length

, stomatogastric nervous system

, organism | segmentally repeated

, unfertilized egg

, pole cell

, egg chamber | early

, dorsal ridge

, nurse cell | restricted

, organism | 80-90% egg length

, nurse cell

, germarium

, embryonic/larval pharynx

, follicle cell

" " embryonic stage | stage 17 , adult stage && oogenesis stage , larval stage | first instar , oogenesis stage&&larval stage | second instar , embryonic stage | stage 8-14 , oogenesis stage&&larval stage | first instar , spermatogenesis && adult stage , oogenesis stage | stage S8 && adult stage | female , embryonic stage | blastoderm , oogenesis stage | stage S10 && adult stage | female , oogenesis stage&&larval stage | third instar " " germline cell

, female germline stem cell

, gonad

, female germline stem cell | restricted

, pole cell

, male germline stem cell

, nurse cell

,

ubiquitous , oocyte

" "lethal,polyphasic,female sterile,recessive,viable,fertile,male fertile,visible,cold sensitive,heat sensitive,female fertile,somatic clone,wild-type,dominant,cytokinesis defective,grandchildless,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,feeding behavior defective,decreased cell growth,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "egg chamber,adult thorax & trichome | somatic clone,adult thorax & microchaeta | somatic clone,dorsal fine hair,temperature conditional,ovary,germline cell,female,spectrosome,nurse cell fusome,nurse cell,germarium cap cell,eye,cold sensitive,embryonic/first instar larval cuticle,arista lateral,arista central core,leg,joint,denticle belt,ectopic,stage S6 oocyte,testis,egg,maternal effect,chorion,stage S4 oocyte,oocyte,dorsal appendage,denticle,embryonic epidermis,embryonic segment,embryonic head,cephalopharyngeal skeleton,adult abdomen & trichome | somatic clone,somatic clone,sternopleural bristle,male,sex comb,denticle row 2,denticle row 3,wing hair,adult thorax & trichomeBx-MS1096,trichome,precursor,ommatidium,interommatidial bristle,rhabdomereGMR.PF,tarsal segment,adult thorax & microchaetaBx-MS1096,denticle row 1,posterior compartment,filamentous actin & embryonic/first instar larval cuticle | ectopicptc-559.1,filamentous actin & embryonic/first instar larval cuticle | ectopic | somatic clone,supernumerary,chaeta,mesothoracic tergum" FBgn0001075 ft fat http://flybase.org/reports/FBgn0001075 "FBgn0002120, FBgn0014266" protein_coding_gene cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24292 cadherin binding ; GO:0045296 | inferred from physical interaction with ds calcium ion binding ; GO:0005509 | inferred from direct assay receptor activity ; GO:0004872 | inferred from sequence or structural similarity "homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 |... electronic annotation with InterPro:IPR002126 <> regulation of organ growth ; GO:0046620 |... genetic interaction with wts <> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 |... mutant phenotype <> wing disc development ; GO:0035220 |... mutant phenotype <> regulation of tube length, open tracheal system ; GO:0035159 |... mutant phenotype <> single organismal cell-cell adhesion ; GO:0016337 |... mutant phenotype <> negative regulation of imaginal disc growth ; GO:0045571 | traceable author statement <> tissue development ; GO:0009888 |... mutant phenotype <> establishment of tissue polarity ; GO:0007164 |... mutant phenotype <> imaginal disc growth ; GO:0007446 |... mutant phenotype <> establishment of planar polarity ; GO:0001736 |... mutant phenotype <> negative regulation of cell proliferation ; GO:0008285 |... mutant phenotype <> negative regulation of imaginal disc growth ; GO:0045571 |... mutant phenotype <> regulation of growth ; GO:0040008 |... mutant phenotype inferred from genetic interaction with RpL36 <> microtubule cytoskeleton organization involved in establishment of planar polarity ; GO:0090176 |... mutant phenotype <> establishment of tissue polarity ; GO:0007164 | non-traceable author statement <> pupal development ; GO:0035209 |... mutant phenotype <> equator specification ; GO:0045317 |... mutant phenotype <> peptide cross-linking ; GO:0018149 |... physical interaction with UniProtKB:Q24292 <> negative regulation of growth ; GO:0045926 |... mutant phenotype <> establishment of ommatidial planar polarity ; GO:0042067 |... mutant phenotype <> cell-cell adhesion mediated by cadherin ; GO:0044331 |... direct assay <> regulation of imaginal disc growth ; GO:0045570 |... mutant phenotype <> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <> cell morphogenesis involved in differentiation ; GO:0000904 |... mutant phenotype <> cell proliferation ; GO:0008283 |... mutant phenotype <> calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 |... sequence or structural similarity <> imaginal disc pattern formation ; GO:0007447 |... mutant phenotype <> establishment of ommatidial planar polarity ; GO:0042067 |... mutant phenotype inferred from genetic interaction with fz <> homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 |... sequence or structural similarity <> establishment of body hair planar orientation ; GO:0048105 |... mutant phenotype <> heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 |... physical interaction with ds <> calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | non-traceable author statement <> negative regulation of gene expression ; GO:0010629 |... mutant phenotype <> imaginal disc-derived wing morphogenesis ; GO:0007476 |... mutant phenotype <> establishment of planar polarity ; GO:0001736 |... mutant phenotype inferred from genetic interaction with ds <> establishment of epithelial cell apical/basal polarity ; GO:0045198 |... mutant phenotype <> hippo signaling ; GO:0035329 |... genetic interaction with wts <> calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 |... direct assay <> regulation of protein localization ; GO:0032880 |... mutant phenotype <> ommatidial rotation ; GO:0016318 | traceable author statement <> negative regulation of Wnt signaling pathway ; GO:0030178 | traceable author statement <> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement <> establishment or maintenance of polarity of larval imaginal disc epithelium ; GO:0016336 |... mutant phenotype" integral component of membrane ; GO:0016021 | traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | non-traceable author statement "Ft, l(2)ft, l(2)k07918, CT11259, CG3352, 79/18, l(2)79/18, l(2)fat, l(2)gd-1, l(2)gd2, l(2)gd-l, l(2)fd, l(2)24Da, ft, Dm Fat, fat, Fat" "IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR002126:Cadherin, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR015919:Cadherin-like, IPR027397:Catenin binding domain, IPR020894:Cadherin conserved site, IPR001881:EGF-like calcium-binding domain" CG3352 11-Aug-17 DroID_v2017_08 "Drer\LOC568600, Drer\dchs1b, Drer\si:dkey-22o22.2, Drer\dchs1a, Drer\si:ch211-186j3.6, Drer\fat1a, Drer\fat1b, Drer\fat2, Drer\fat4, Drer\fat3a, Drer\dchs2, Drer\cdh23" - "Cele\cdh-3, Cele\hmr-1, Cele\cdh-4, Cele\cdh-1" "Xtro\dchs2, Xtro\fat4, Xtro\fat1" "Mmus\Fat3, Mmus\Gm281, Mmus\Cdh23, Mmus\Fat4, Mmus\Dchs1, Mmus\Fat1, Mmus\Fat2" "Hsap\FAT2, Hsap\DCHS2, Hsap\FAT3, Hsap\DCHS1, Hsap\FAT1, Hsap\CDH23, Hsap\DLK2, Hsap\FAT4" " embryonic stage , larval stage " " ectoderm

, embryonic/larval pharynx

, embryonic/larval hindgut

, neuron &&of larval optic lobe

, imaginal disc

, embryonic/larval foregut

" "lethal,recessive,visible,dominant,hyperplasia,lethal - all die before end of embryonic stage,some die during embryonic stage,size defective,cell polarity defective,partially lethal - majority die,planar polarity defective,increased cell number,somatic clone,decreased cell number,lethal - all die before end of pupal stage,some die during pupal stage,cell non-autonomous,mitotic cell cycle defective,viable,developmental rate defective,decreased cell size,cell autonomous,lethal - all die before end of P-stage,some die during pharate adult stage,cell shape defective,cell growth defective,neuroanatomy defective,progressive,cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,wing,wing disc,external sensory organ,macrochaeta,microchaeta,eye disc,abdomen,embryonic/larval dorsal trunk,embryonic/larval glial cell,ommatidium,somatic clone,cell non-autonomous,photoreceptor cell R3,photoreceptor cell R4,ectopic,wing vein,wing & chaeta | somatic clone,mesothoracic tergum,mesothoracic tergum & chaeta | somatic clone,interommatidial bristle,supernumerary,eye,adult thorax,intestinal stem cell,trichome & abdominal tergite | somatic clone | cell non-autonomous‘±Tub84B.PL,adult abdomen,crystal cell,tergite,adult cuticle,denticle belt,adult antennal segment,leg,adult head,vibrissae,pigment cell,wing blade,wing hair,eye photoreceptor cell,cell autonomous,progressive,autophagic vacuole | progressive | somatic clone,trichome,cuticle,wing & chaeta,prothoracic leg disc,mesothoracic leg disc,metathoracic leg disc,embryonic/larval brain,microtubuleen-e16E,denticle row 1,dorsal,posterior,crossvein" FBgn0003892 ptc patched http://flybase.org/reports/FBgn0003892 "FBgn0013766, FBgn0015537, FBgn0064818" protein_coding_gene hedgehog receptor activity ; GO:0008158 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with l(2)tid lipoprotein particle receptor activity ; GO:0030228 | inferred from direct assay transmembrane signaling receptor activity ; GO:0004888 | non-traceable author statement hedgehog receptor activity ; GO:0008158 | inferred from mutant phenotype "regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype regulation of protein import into nucleus ; GO:0042306 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype anterior/posterior pattern specification ; GO:0009952 | non-traceable author statement negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from genetic interaction with Su(fu) negative regulation of smoothened signaling pathway ; GO:0045879 | traceable author statement proteolysis ; GO:0006508 | traceable author statement dephosphorylation ; GO:0016311 | traceable author statement wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement embryonic pattern specification ; GO:0009880 | traceable author statement smoothened signaling pathway ; GO:0007224 | traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype somatic stem cell division ; GO:0048103 | traceable author statement smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with hh germ-line stem cell division ; GO:0042078 | traceable author statement eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype anterior/posterior lineage restriction, imaginal disc ; GO:0048099 | traceable author statement Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | non-traceable author statement regulation of apoptotic process ; GO:0042981 | inferred from genetic interaction with hid gonad development ; GO:0008406 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype" endocytic vesicle ; GO:0030139 | inferred from direct assay cilium ; GO:0005929 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay fusome ; GO:0045169 | colocalizes_with inferred from direct assay "ptc, Ptc, Ptc_Dm, l(2)k02507, rubr, PTC, tuf, pat, Conf, CG2411, BcDNA:RH36596, ptch, dPtc, Ptch, com4" "IPR000731:Sterol-sensing domain, IPR003392:Protein patched/dispatched, IPR004766:Transmembrane receptor, patched" CG2411 11-Aug-17 DroID_v2017_08 "Drer\ptch1, Drer\ptch2" Scer\NCR1 "Cele\ptr-1, Cele\ptc-2, Cele\ptc-3, Cele\ptc-1, Cele\ptr-11" "Xtro\ptch1, Xtro\ptch2" "Mmus\Ptch1, Mmus\Ptch2" "Hsap\PTCH1, Hsap\PTCH2" " embryonic stage , larval stage | third instar " " labrum

, Malpighian tubule

, analia

, neuroblast

, head

, embryonic/larval hindgut

, dorsal mesothoracic disc | anterior/posterior compartment boundary

,

segment polarity " " larval stage | third instar stage 2 , larval stage | third instar " " eye-antennal disc

restricted , dorsal mesothoracic disc | anterior/posterior compartment boundary

" "partially lethal - majority die,visible,viable,lethal,somatic clone,recessive,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,wild-type,increased cell death,mitotic cell cycle defective,cell lethalcell lethal,cell non-autonomous,lethal - all die before end of larval stage,some die during larval stage,planar polarity defective,cell migration defective,neuroanatomy defective,segment polarity phenotype,heat sensitive" "wing vein L3,wing vein L4,ectopic,somatic clone,wing margin bristle,ocellar triangle,fronto-orbital plate,frons,eye,head capsule & cuticle | ectopic,head bristle,ocellus,head capsule,antenna,eye-antennal disc,EL neuron,neuroblast NB7-3,neuroblast NB4-2,wing,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,photoreceptor cell,morphogenetic furrow,eye equator,gonad,scutellar bristle,adult head,cell non-autonomous,ommatidium,eye disc,antennal disc,wing margin,triple row,double row,head,anterior compartment,costal cell,wing vein,macrochaeta,wing disc,scutellum,1st posterior cell,anterior,sense organ,basal stalk,interfollicle cell,supernumerary,follicle stem cell,ovariole,follicle cell,oocyte,polar follicle cell,follicle cell & nucleus | somatic clone,border follicle cell,oocyte nucleus,germarium region 3,sex comb,eye photoreceptor cell,wing cell,ocellar bristle,imaginal disc,sensillum campaniformium of dorsal radius,female gonopod,dorsal,epiproct,scutellum & macrochaeta | somatic clone,embryonic/first instar larval cuticle,embryonic gnathal segment,RP2 motor neuron,Keilin's organ,embryonic epidermis,dorsal thick hair,denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,apodeme,embryonic somatic muscle,lateral,embryonic head,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,genital disc primordium,embryonic optic lobe,denticle row 1,denticle row 2,Bolwig organ,tergite,posterior vertical bristle,medial ocellus,egg chamber,germline clone,leg,sensory mother cell,sensillum campaniformium of dorsal radius Sc25,precursor,sensillum campaniformium of dorsal radius Sc4d,sensillum campaniformium of dorsal radius Sc12,marginal cell,embryonic/larval tracheal system,embryonic/larval ganglionic branch,wing basal cell 1,eye disc & morphogenetic furrow,photoreceptor cell & axon,denticle,germline cell,dorsal neurohemal organ,mesothoracic tarsal bristle longitudinal row 7,mesothoracic tarsal bristle longitudinal row 5,mesothoracic tarsal bristle longitudinal row 5.5,wing vein L2,microchaeta & head,embryonic segment,commissure,midline glial cell,ventral nerve cord,anterior commissure,posterior commissure,medial longitudinal fascicle,pCC neuron,wing sensillum,anterior crossvein,submarginal cell,embryonic/larval visceral branch,embryonic/larval dorsal branch,wing vein L5,posterior crossvein,pseudotrachea,heat sensitive,tergite & macrochaetahs.PB,wing blade" FBgn0014179 gcm glial cells missing http://flybase.org/reports/FBgn0014179 FBgn0014259 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from biological aspect of ancestor with PANTHER:PTN000275807 enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay" "hemopoiesis ; GO:0030097 | traceable author statement glial cell differentiation ; GO:0010001 | traceable author statement posterior head segmentation ; GO:0035289 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement neuron differentiation ; GO:0030182 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype regulation of phagocytosis ; GO:0050764 | inferred from mutant phenotype glial cell differentiation ; GO:0010001 | inferred from mutant phenotype embryonic crystal cell differentiation ; GO:0035165 | inferred from mutant phenotype crystal cell differentiation ; GO:0042688 | NOT inferred from mutant phenotype gliogenesis ; GO:0042063 | inferred from mutant phenotype plasmatocyte differentiation ; GO:0042387 | traceable author statement retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype positive regulation of glial cell proliferation ; GO:0060252 | inferred from mutant phenotype glial cell fate determination ; GO:0007403 | inferred from mutant phenotype positive regulation of glial cell differentiation ; GO:0045687 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype embryonic plasmatocyte differentiation ; GO:0035164 | traceable author statement positive regulation of gene expression ; GO:0010628 | inferred from direct assay hemocyte development ; GO:0007516 | non-traceable author statement gliogenesis ; GO:0042063 | inferred from mutant phenotype inferred from genetic interaction with gcm2 dendrite morphogenesis ; GO:0048813 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay hemocyte development ; GO:0007516 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype lymph gland plasmatocyte differentiation ; GO:0035169 | traceable author statement negative regulation of crystal cell differentiation ; GO:0042690 | inferred from mutant phenotype glial cell differentiation ; GO:0010001 | inferred from mutant phenotype inferred from genetic interaction with gcm2 plasmatocyte differentiation ; GO:0042387 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "GCM1, glide, GCM, glide/gcm, N7-4, Gcm, ucc, l(2)N7-4, CG12245, gcm, GCMa" IPR003902:Transcription regulator GCM domain CG12245 11-Aug-17 DroID_v2017_08 Drer\gcm2 - - "Xtro\gcm1, Xtro\gcm2" "Mmus\Gcm2, Mmus\Gcm1" "Hsap\GCM2, Hsap\GCM1" " embryonic stage | cellular blastoderm , embryonic stage | stage 11-13 , embryonic stage , embryonic stage | stage12 , embryonic stage | stage 9-11 , embryonic stage | stage 5-11 , embryonic stage | stage 10 , embryonic stage | stage 11-14 , embryonic stage | stage 11-17 , embryonic stage | stage 12-15 " " neuroblast NB6-4

, sense organ

, multidendritic sensory organ precursor cell

, tritocerebral neuroblast | subset

, head mesoderm

, medial-most cell body glial cell

, interface glial cell

, embryonic brain

, embryonic peripheral nervous system

, interface glial cell | precursor

, embryonic peripheral nervous system | restricted

, peripheral glial cell

, embryonic/larval hemocyte

, glial cell

, embryonic glial cell

, abdominal basiconical sensillum dbd

, neuroblast NB1-3

, lateral ectoderm

" " embryonic stage , embryonic stage | cellular blastoderm , embryonic stage | stage 11-17 , embryonic stage | stage 11-14 " " peripheral glial cell

, head mesoderm

, sense organ

, interface glial cell

, embryonic peripheral nervous system

, embryonic brain

, glial cell

" "viable,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,heat sensitive,melanotic mass phenotype,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,visible,dominant,developmental rate defective,increased cell death,somatic clone,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,increased cell number,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "wing margin,sense organ,ectopic,sense organ & wing,glial cell,macrophage,embryonic/larval ganglionic branch,embryonic/larval glial cell,longitudinal connective,central nervous system,hemocyte,glioblast,embryonic neuroblast,nerve,embryonic/larval peritracheal cell,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,presumptive embryonic/larval central nervous system,lamina,somatic clone,eye photoreceptor cell stalk,ventral longitudinal muscle | embryonic stage,medulla neuropil glial cell,heat sensitive,melanotic mass,lamellocyte,plasmatocyte,mesothoracic tergum & macrochaeta | supernumerary | conditional ts,wing sensillum,embryonic/larval hemocyte,dMP2 neuron,pCC neuron,PNS exit glial cell,peripheral glial cell,intersegmental nerve,segmental nerve,embryonic/larval somatic muscle,embryonic/larval nervous system,dendrite,axon | embryonic stage,commissure,neuron,interface glial cell,metathoracic laterotergite & macrochaeta | supernumerary,scutum & macrochaeta | supernumerary,scutellum & macrochaeta | supernumerary,chaeta,supernumerary,macrochaeta,mesothoracic tergum & macrochaeta | supernumerary,fascicle,support cell of the dorsal bipolar dendritic cell,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,abdominal segment 6,ventral abdominal cluster,ventral thoracic cluster,lch3 neuron,lch5 neuron,segmental nerve pioneer neuron,aCC neuron,embryonic/larval neuron,intermediate longitudinal fascicle,precursor,sensory neuron,neuropil associated CNS glial cell,ventral longitudinal muscle,wing & thecogen cell | somatic clone,wing & neuron | supernumerary | somatic clone,embryonic maxillary segment,embryonic mandibular segment,subperineurial glial cell,CNS glial cell,crystal cell,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial ligament cell & stage 16 embryo,lch5 ligament attachment cell,neuroblast NB6-4,neuroblast NB6-4 of thorax,neuroblast,mesothoracic tergum & macrochaeta | supernumerary | conditional tshs.PB,campaniform sensillum L3-3 of wing vein L3,embryonic/larval visceral muscle,ventral nerve cord,anterior commissure,posterior commissure,embryonic epidermis,dorsal,type II neuroblast,crystal cell primordium,bipolar dendrite neuron,outer photoreceptor cell,optic lobe,medulla cortex & glial cell | somatic clone,wing & sensillum campaniformium | supernumerary | somatic clone" FBgn0267615 CR45953 - http://flybase.org/reports/FBgn0267615 non_protein_coding_gene - - - CR45953 - CR45953 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001041 fs(3)HO5A female sterile (3) HO5A http://flybase.org/reports/FBgn0001041 - gene - - - "fs(3)f1, fs(3)f1[5A], fs(3)HO5A, fs(3)H05A" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" "ovary,oviduct,germarium,vitellarium,calyx of oviduct" FBgn0011817 nmo nemo http://flybase.org/reports/FBgn0011817 "FBgn0014365, FBgn0019910, FBgn0023460, FBgn0044612, FBgn0046458, FBgn0062087" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR003527, InterPro:IPR017441 MAP kinase activity ; GO:0004707 | inferred from biological aspect of ancestor with PANTHER:PTN001934972 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein kinase activity ; GO:0004672 | inferred from direct assay" gravitaxis ; GO:0042332 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from genetic interaction with gish protein phosphorylation ; GO:0006468 | non-traceable author statement imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 compound eye development ; GO:0048749 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from genetic interaction with fz ommatidial rotation ; GO:0016318 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with arm inferred from genetic interaction with sgg inferred from genetic interaction with fz2 inferred from genetic interaction with Axn imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 establishment of planar polarity ; GO:0001736 | traceable author statement positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:1201387 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 "Nlk, CG7892, Nemo, NEMO/NLK, NEMO, adk, clone 2.43, anon-WO0172774.138, anon-EST:Gibbs3, anon-EST:Liang-2.43, anon-WO0140519.256, anon-WO0118547.332, nmo, nemo, adk1, Nmo, ORE-6, NLK" "IPR000719:Protein kinase domain, IPR003527:Mitogen-activated protein (MAP) kinase, conserved site, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG7892 11-Aug-17 DroID_v2017_08 "Drer\nlk1, Drer\nlk2" "Scer\FUS3, Scer\KSS1" Cele\lit-1 "Xtro\nlk, Xtro\nlk.2" Mmus\Nlk Hsap\NLK " embryonic stage -- adult stage , larval stage | third instar " morphogenetic furrow

"lethal,planar polarity defective,somatic clone,lethal - all die before end of P-stage,some die during pharate adult stage,viable,fertile,visible,behavior defective,dominant,cell polarity defective,recessive,gravitaxis defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,decreased cell size,partially lethal - majority die,germline clone,maternal effect,cell death defective,locomotor rhythm defective" "ommatidium,somatic clone,wing vein,ectopic,ommatidial precursor cluster,eye,wing,interommatidial bristle,secondary pigment cell,NMJ bouton,type I bouton,NMJ bouton | third instar larval stage,denticle belt,embryonic/first instar larval cuticle,embryonic head,dorsal closure embryo,wing blade,germline clone,maternal effect,denticle,embryonic segment,tertiary pigment cell,crossvein,mesothoracic tergum & macrochaeta,head bristle,wing vein L2,posterior crossvein,anterior,abdominal tergite & microchaeta69B,abdominal tergite & macrochaeta69B,scutum & macrochaetaap-md544,scutellar bristle,wing margin,wing cell,submarginal cell" DRSC11377 E -0.03788878 -1.322827467 -1.899991609 0.684221664 -0.053329763 0.889884637 FBgn0033421 CG1888 - http://flybase.org/reports/FBgn0033421 protein_coding_gene - - - CG1888 IPR031934:Protein of unknown function DUF4769 CG1888 11-Aug-17 DroID_v2017_08 - - - - - - viable embryonic/larval hemocyte | third instar larval stage FBgn0013432 bcn92 bcn92 http://flybase.org/reports/FBgn0013432 "FBgn0045295, FBgn0047082" protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of pain ; GO:0019233 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "EG:87B1.6, CG3717, NEST:bs15a04, BcDNA:RE57896, bcn92" IPR008011:Complex 1 LYR protein CG3717 11-Aug-17 DroID_v2017_08 Drer\lyrm4 Scer\ISD11 - - Mmus\Lyrm4 Hsap\LYRM4 "partially lethal - majority die,some die during pupal stage" FBgn0264855 AP-2alpha "Adaptor Protein complex 2, alpha subunit" http://flybase.org/reports/FBgn0264855 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from direct assay protein transporter activity ; GO:0008565 | inferred from mutant phenotype "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR003164, InterPro:IPR008152, InterPro:IPR009028, InterPro:IPR013038, InterPro:IPR015873 regulation of endocytosis ; GO:0030100 | inferred from direct assay asymmetric cell division ; GO:0008356 | traceable author statement synaptic vesicle endocytosis ; GO:0048488 | inferred from direct assay synaptic vesicle coating ; GO:0016183 | traceable author statement protein transport ; GO:0015031 | inferred from direct assay synaptic vesicle transport ; GO:0048489 | traceable author statement ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype vesicle coating ; GO:0006901 | traceable author statement positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement" plasma membrane ; GO:0005886 | inferred from direct assay AP-2 adaptor complex ; GO:0030122 | inferred from mutant phenotype synaptic vesicle ; GO:0008021 | traceable author statement coated vesicle ; GO:0030135 | traceable author statement clathrin-coated pit ; GO:0005905 | inferred from direct assay "ada, alpha-Adaptin, alpha-ada, alpha-Ada, l(2)SH0460, l(2)SH2 0460, CG4260, AP2, alpha-adaptin, cg4260, D-alphaAda, alpha, AP-2, D-Ada, dAP-2a, l(2)06694, CG31654, Alpha-Adaptin, AP-2alpha, MENE(2L)-A, MENE (2L)-A, apl3, Ada, alphaAda" "IPR002553:Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR003164:Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain, IPR008152:Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain, IPR009028:Coatomer/calthrin adaptor appendage, C-terminal subdomain, IPR011989:Armadillo-like helical, IPR013041:Coatomer/clathrin adaptor appendage, Ig-like subdomain, IPR016024:Armadillo-type fold, IPR017104:Adaptor protein complex AP-2, alpha subunit" CG4260 11-Aug-17 DroID_v2017_08 Drer\ap2a1 Scer\APL3 Cele\apa-2 Xtro\ap2a2 "Mmus\Ap2a1, Mmus\Ap2a2" "Hsap\AP2A2, Hsap\AP2A1" " embryonic stage , embryonic stage && adult stage , embryonic stage&&adult stage , larval stage , embryonic stage && larval stage " " embryonic brain

, imaginal disc

, embryonic ventral nervous system

, garland cell

" " embryonic stage , embryonic stage | stage 8-12 , pupal stage , embryonic stage | stage >=8 , embryonic stage | early , larval stage , embryonic stage | stage >=14 , embryonic stage | stage >=13 , embryonic stage | late , embryonic stage | stage 8-11 " " proctodeum | primordium

, posterior midgut proper primordium

, sensory mother cell

, embryonic nervous system

, sensory mother cell

, ventral nerve cord

, bouton

, endoderm

, embryonic stomatogastric nervous system

, antenno-maxillary complex

, neuromuscular junction

, fat body primordium

, embryonic peripheral nervous system

, garland cell

, visceral mesoderm

, chordotonal organ

, embryonic/larval somatic muscle

, neuroblast

, head mesoderm

, cephalic furrow

, supraesophageal ganglion

, adult midgut precursor

, anterior midgut proper primordium

" DRSC00800 IE 1.505841149 1.315557142 0.293145832 1.752373102 0.954336378 0.627402719 FBgn0024277 trio trio http://flybase.org/reports/FBgn0024277 "FBgn0015758, FBgn0028051, FBgn0028162, FBgn0035180, FBgn0035182, FBgn0046252" protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with HGNC:12303 inferred from direct assay actin cytoskeleton organization ; GO:0030036 | inferred from expression pattern lateral inhibition ; GO:0046331 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype inferred from genetic interaction with Lar inferred from genetic interaction with Rac1 axon guidance ; GO:0007411 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with Abl axon extension ; GO:0048675 | inferred from mutant phenotype positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from direct assay response to BMP ; GO:0071772 | inferred from genetic interaction with Mad axon guidance ; GO:0007411 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from direct assay central nervous system development ; GO:0007417 | inferred from mutant phenotype inferred from genetic interaction with Abl mushroom body development ; GO:0016319 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with Lar inferred from genetic interaction with Rac1 axon target recognition ; GO:0007412 | inferred from genetic interaction with Liprin-α regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with LIMK1 extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "Trio, UNC-73/Trio, l(3)036810, CG18214, DTrio, l(3)S[1386/06], l(3)S[1372/3], l(3)S138606, l(3)S137203, l(3)S095914, l(3)S036810, 1386/06, 1372/03, 0959/14, 0368/10, M89, BEST:LD36950, CG9208, trio, TRIO, l(3)6D104, l(3)trio, dTrio" "IPR018159:Spectrin/alpha-actinin, IPR000219:Dbl homology (DH) domain, IPR001251:CRAL-TRIO lipid binding domain, IPR001452:SH3 domain, IPR001849:Pleckstrin homology domain, IPR002017:Spectrin repeat, IPR011993:PH domain-like, IPR001331:Guanine-nucleotide dissociation stimulator, CDC24, conserved site" CG18214 11-Aug-17 DroID_v2017_08 "Drer\arhgef25a, Drer\LOC569231, Drer\si:dkey-65j6.2, Drer\arhgef3, Drer\sestd1, Drer\triob, Drer\arhgef3l, Drer\LOC101883939, Drer\plekhg4, Drer\zgc:158766, Drer\net1, Drer\trioa, Drer\ccdc142, Drer\kalrnb, Drer\arhgef25b, Drer\arhgef16, Drer\ngef, Drer\kalrna, Drer\quo, Drer\arhgef40" "Scer\ROM1, Scer\ROM2, Scer\TUS1, Scer\CDC24" "Cele\ephx-1, Cele\unc-73" "Xtro\arhgef40, Xtro\sestd1, Xtro\arhgef16, Xtro\kalrn, Xtro\trio, Xtro\net1, Xtro\arhgef25" "Mmus\Arhgef26, Mmus\Sestd1, Mmus\Arhgef40, Mmus\Plekhg4, Mmus\Arhgef16, Mmus\Arhgef3, Mmus\D630003M21Rik, Mmus\Net1, Mmus\Trio, Mmus\Mcf2, Mmus\Arhgef25, Mmus\Arhgef15, Mmus\Kalrn, Mmus\Ngef" "Hsap\SESTD1, Hsap\MCF2, Hsap\ARHGEF25, Hsap\PLEKHG4B, Hsap\PLEKHG4, Hsap\ARHGEF1, Hsap\TRIO, Hsap\ARHGEF40, Hsap\MCF2L2, Hsap\ARHGEF3, Hsap\ARHGEF15, Hsap\NGEF, Hsap\KALRN, Hsap\ARHGEF16, Hsap\NET1" " adult stage , larval stage | third instar , larval stage && pupal stage , larval stage && adult stage , embryonic stage , embryonic stage | stage 12-17 " " mushroom body

, lamina

, neuron

, calyx of mushroom body

, eye disc

, adult brain

, epidermis

, neuron

, longitudinal connective

, mushroom body gamma-lobe

, mushroom body alpha'-lobe

, mushroom body beta'-lobe

, ellipsoid body

, muscle attachment site

, commissure

" "lethal,recessive,neuroanatomy defective,somatic clone,viable,visible,partially lethal - majority live,some die during P-stage,partially lethal - majority die,locomotor behavior defective,sterile,wild-type,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of prepupal stage,some die during prepupal stage" "adult mushroom body,somatic clone,wing,vertical branch of mushroom body,medial branch of mushroom body,ellipsoid body,photoreceptor cell & axon,intersegmental nerve,longitudinal connective,abdominal segmental nerve,RP3 motor neuron,embryonic/larval neuromuscular junction,NMJ bouton,photoreceptor cell & axonGMR.PF,photoreceptor cell R7,photoreceptor cell & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,axon | somatic clone | third instar larval stage,embryonic somatic muscle,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,presumptive embryonic/larval central nervous system,embryonic/larval central nervous system,commissure,anterior commissure,posterior commissure,eye photoreceptor cell,embryonic central nervous system & axon,embryonic peripheral nervous system & axon,eye,photoreceptor cell,photoreceptor cell & eye discGMR.PF,ommatidium,medulla,chaeta,supernumerary,trichogen cell" FBgn0010434 cora coracle http://flybase.org/reports/FBgn0010434 "FBgn0005646, FBgn0022032" protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR008379 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 "adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype cell-cell junction organization ; GO:0045216 | traceable author statement cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype dorsal closure ; GO:0007391 | non-traceable author statement chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | traceable author statement embryo development ; GO:0009790 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | traceable author statement maintenance of imaginal disc-derived wing hair orientation ; GO:0035321 | inferred from mutant phenotype heart process ; GO:0003015 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype actomyosin structure organization ; GO:0031032 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 dorsal closure ; GO:0007391 | traceable author statement septate junction assembly ; GO:0019991 | traceable author statement establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype protein targeting to membrane ; GO:0006612 | traceable author statement" septate junction ; GO:0005918 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay septate junction ; GO:0005918 | inferred from direct assay smooth septate junction ; GO:0005920 | inferred from direct assay septate junction ; GO:0005918 | traceable author statement spectrosome ; GO:0045170 | NOT inferred from direct assay cytoskeleton ; GO:0005856 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 fusome ; GO:0045169 | NOT inferred from direct assay "Cor, cora, cor, COR, CG11949, D4.1, l(2)k08713, Cora, Coracle, mdcds_14526" "IPR000299:FERM domain, IPR008379:Band 4.1, C-terminal, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR014847:FERM adjacent (FA), IPR018979:FERM, N-terminal, IPR018980:FERM, C-terminal PH-like domain, IPR019747:FERM conserved site, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain" CG11949 11-Aug-17 DroID_v2017_08 "Drer\epb41l3a, Drer\epb41l3b, Drer\si:dkey-178k16.1, Drer\wu:fi46h04, Drer\epb41b" - Cele\frm-1 "Xtro\epb41l1, Xtro\epb41, Xtro\epb41l3, Xtro\epb41l2" "Mmus\Epb41l3, Mmus\Epb41, Mmus\Epb41l2, Mmus\Epb41l1, Mmus\2310002L09Rik" "Hsap\EPB41L2, Hsap\EPB41L1, Hsap\EPB41, Hsap\EPB41L3" " larval stage | second instar , larval stage | first instar , embryonic stage | 8-20 hr , larval stage , embryonic stage | 4-20 hr " " embryonic stage | stage >=13 , embryonic stage | stage >=12 , adult stage && oogenesis stage | early , larval stage && pupal stage " " scolopidium

, abdominal 1--7 lateral pentascolopidial chordotonal organ lch5 | precursor

, epidermis

, terminal filament

, dorsal mesothoracic disc

, embryonic/larval salivary gland

, germarium cap cell

, embryonic/larval trachea

, eye-antennal disc

, follicle cell

, chordotonal organ

, embryonic/larval foregut

, embryonic/larval hindgut

" "lethal,recessive,neuroanatomy defective,neurophysiology defective,viable,fertile,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,cell polarity defective,cell lethal,partially,somatic clone,visible,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,immune response defective" "embryonic/first instar larval cuticle,dorsal,embryonic/larval salivary gland,eye,anterior,interommatidial bristle,ommatidium,embryonic dorsal epidermis,eye equator,embryonic head,embryonic ganglionic branch & embryonic tracheole,dorsal trunk primordium,wing hair,dorsal closure embryo,presumptive embryonic salivary gland,presumptive embryonic/larval tracheal system,pleated septate junction,septate junction | embryonic stage,septate junction,denticle belt,ocellus,ocellar bristle,interocellar bristle,embryonic/larval tracheal system,indirect flight muscle,smooth septate junctionNP3084" FBgn0010316 dap dacapo http://flybase.org/reports/FBgn0010316 "FBgn0010576, FBgn0015920" protein_coding_gene cyclin-dependent protein serine/threonine kinase inhibitor activity ; GO:0004861 | inferred from direct assay signal transduction by p53 class mediator ; GO:0072331 | inferred from electronic annotation with InterPro:IPR029841 cell cycle arrest ; GO:0007050 | inferred from electronic annotation with InterPro:IPR003175 negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from mutant phenotype sensory organ precursor cell division ; GO:0045035 | inferred from mutant phenotype histoblast morphogenesis ; GO:0007488 | inferred from mutant phenotype negative regulation of cell cycle ; GO:0045786 | inferred from direct assay regulation of protein kinase activity ; GO:0045859 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype negative regulation of cell cycle ; GO:0045786 | traceable author statement negative regulation of protein dephosphorylation ; GO:0035308 | inferred from direct assay germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | traceable author statement oogenesis ; GO:0048477 | traceable author statement nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "dap, Dap, p21[dacapo], dacapo/cyclin-dependent kinase interactor 4, Decapo, CIB1, CDKN2B, P15, CG1772, E(Sev-CycE)2B, Cdi4, CDI4, l(2)04454, cdi4, p27[Dap], p27cip/kip, p21, p27, Dac, DAP, dacapo" "IPR003175:Cyclin-dependent kinase inhibitor, IPR029841:Cyclin-dependent kinase inhibitor 1, vertebrate" CG1772 11-Aug-17 DroID_v2017_08 "Drer\cdkn1d, Drer\cdkn1ba, Drer\cdkn1a, Drer\cdkn1ca, Drer\cdkn1bb, Drer\cdkn1cb" - "Cele\cki-2, Cele\cki-1" - "Mmus\Cdkn1c, Mmus\Cdkn1a, Mmus\Cdkn1b" "Hsap\CDKN1B, Hsap\CDKN1A, Hsap\CDKN1C" " embryonic stage | stage 6 , embryonic stage , embryonic stage | early , larval stage " " cephalic furrow

, ventral nerve cord | restricted

, ectoderm

, organism | 0-10% egg length

, morphogenetic furrow

, posterior midgut proper primordium

, embryonic central nervous system

, mesoderm

, amnioserosa

, eye-antennal disc

, ventral furrow

, epidermis

, morphogenetic furrow | posterior to

, supraesophageal ganglion

, peripheral nervous system

, anterior midgut proper primordium

" " embryonic stage | stage 6 , embryonic stage | early , embryonic stage " " amnioserosa

, pole cell

, yolk nucleus

, epidermis

, peripheral nervous system

, ventral nerve cord | restricted

, embryonic central nervous system

" "lethal,partially,recessive,partially lethal - majority die,mitotic cell cycle defective,neuroanatomy defective,visible,viable,somatic clone,decreased cell death,female sterile,size defective" "macrochaeta,embryonic/larval transverse connective,embryonic/larval dorsal trunk,interface glial cell,embryo,embryonic abdomen & glial cell | ectopic,embryonic epidermis,dorsocentral bristle,trichogen cell,tormogen cell,scutellar bristle,wing hair,wing margin,mesothoracic tergum,chaeta,eye,ommatidium,mitotic cell cycle | ectopic,external sensory organ precursor cell IIIb & S phase,PNS glial cell & S phase,oocyte,germline clone,karyosome,embryonic/larval optic lobe,lch1 neuron,ectopic,follicle cell & nucleus | somatic clone,mitotic cell cycle,eye disc,wing,posterior compartment,embryonic segment,wing cell,follicle stem cell,somatic clone,mitotic cell cycleunspecified,neuroblast NB6-4 of thorax,neuron & embryonic thorax-537.4,dorsal appendage,egg,chorion,G1 phase & external sensory organ precursor cell IIbneur-P72,G1 phase & external sensory organ precursor cell IIaneur-P72,embryonic pericardial cell,cardioblast,wing disc,histoblast,embryonic/larval epidermis,adult abdomen,eye disc posterior to the morphogenetic furrow" FBgn0015420 l(1)16Cb lethal (1) 16Cb http://flybase.org/reports/FBgn0015420 - gene - - - l(1)16Cb - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0003984 vn vein http://flybase.org/reports/FBgn0003984 "FBgn0001609, FBgn0002436, FBgn0010946, FBgn0011493" protein_coding_gene epidermal growth factor receptor binding ; GO:0005154 | traceable author statement epidermal growth factor receptor binding ; GO:0005154 | non-traceable author statement heparin binding ; GO:0008201 | inferred from direct assay epidermal growth factor receptor binding ; GO:0005154 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement haltere development ; GO:0007482 | inferred from mutant phenotype notum cell fate specification ; GO:0035310 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement olfactory learning ; GO:0008355 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype muscle attachment ; GO:0016203 | traceable author statement epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement negative regulation of apoptotic process ; GO:0043066 | traceable author statement border follicle cell migration ; GO:0007298 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | non-traceable author statement epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cell-cell signaling ; GO:0007267 | traceable author statement imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | traceable author statement notum development ; GO:0007477 | inferred from mutant phenotype extracellular region ; GO:0005576 | non-traceable author statement extracellular region ; GO:0005576 | traceable author statement plasma membrane ; GO:0005886 | non-traceable author statement "vn, l(3)vn10567, vein, Vein, Vn, CT29452, P1749, ddd, l(3)L6A, wvn, l(3)rF264, l(3)ddd, l(3)10568, l(3)10567, CG10491, Dm vn" "IPR000742:EGF-like domain, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013032:EGF-like, conserved site, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG10491 11-Aug-17 DroID_v2017_08 "Drer\nrg3b, Drer\nrg1, Drer\nrg2a, Drer\nrg2b" - Cele\igeg-1 Xtro\nrg1 "Mmus\Nrg2, Mmus\Nrg4, Mmus\Nrg3, Mmus\Nrg1" "Hsap\NRG1, Hsap\NRG2, Hsap\NRG3, Hsap\NRG4, Hsap\MYOT" " embryonic stage , embryonic stage | stage <=11 , larval stage&&pupal stage , embryonic stage | stage 10 , embryonic stage | stage >=11 , embryonic stage | blastoderm , pupal stage , larval stage , embryonic stage | stage 16 , embryonic stage | stage 11-12 , embryonic stage | stage 10-15 , embryonic stage | stage 11-14 " " ventral midline | restricted

, central nervous system

, amnioserosa

, scutum | presumptive

, tracheal pit

, peripheral nervous system | restricted

, Keilin's organ

, dorsal mesothoracic disc | restricted

, amnioserosa | precursor

, wing cell

, eye-antennal disc

, ventral thoracic disc

, visceral muscle

, dorsal metathoracic disc

, vMP2 neuron

, epidermis

, somatic muscle

, embryonic foregut

ventral & dorsal & anterior , embryonic central brain

subset , labral segment

, chordotonal organ

, labial segment

, maxillary lobe

, organism | striped & ventro-lateral

, stomodeum

, dMP2 neuron

" " embryonic stage | stage 11-14 , embryonic stage | stage 11-12 " " dMP2 neuron

, vMP2 neuron

" "lethal,recessive,decreased cell number,lethal - all die before end of P-stage,some die during pharate adult stage,learning defective,RU486 conditional,visible,viable,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,partially,some die during larval stage,male sterile,neuroanatomy defective,heat sensitive,partially lethal - majority live,homeotic,mitotic cell cycle defective" "lch5 ligament attachment cell,embryonic/larval midgut,gastric caecum,midgut constriction 1,midgut constriction 2,midgut constriction 3,ventral oblique muscle,ventral longitudinal muscle,dorsal oblique muscle,embryonic/larval somatic muscle,abdominal 2 dorsal acute muscle 1,precursor,abdominal 3 dorsal acute muscle 1,abdominal 4 dorsal acute muscle 1,abdominal 5 dorsal acute muscle 1,abdominal 6 dorsal acute muscle 1,abdominal 7 dorsal acute muscle 1,adult midgut precursor cell,midgut,wing vein L4,anterior crossvein,wing,border follicle cell & filopodiumslbo.2.6,border follicle cell,wing vein,ocellus,ocellar bristle,postvertical bristle,adult cuticle & head capsule | dorsal,wing disc,haltere disc,embryonic/larval brain,ventral nerve cord,wing vein L3,posterior crossvein,crossvein,embryonic central brain,dMP2 neuron,interface glial cell,longitudinal connective,lateral longitudinal fascicle,intermediate longitudinal fascicle,Keilin's organ,embryonic/first instar larval cuticle,ventral,Kolbchen,scutum,muscle attachment site,larva,sensory neuron & axon & embryo,chordotonal organ,anterior fascicle sensory neuron,posterior fascicle sensory neuron,imaginal disc,abdominal 2 lateral longitudinal muscle 1,abdominal 3 lateral longitudinal muscle 1,abdominal 4 lateral longitudinal muscle 1,abdominal 5 lateral longitudinal muscle 1,abdominal 6 lateral longitudinal muscle 1,abdominal 7 lateral longitudinal muscle 1,abdominal 2 ventral acute muscle 2,abdominal 3 ventral acute muscle 2,abdominal 4 ventral acute muscle 2,abdominal 5 ventral acute muscle 2,abdominal 6 ventral acute muscle 2,abdominal 7 ventral acute muscle 2,midline glial cell,ventral nerve cord commissure,ectopic,wing margin,somatic clone,eye,dorsal mesothoracic disc & peripodial epithelium | somatic clone‘±Tub84B.PL,dorsal mesothoracic disc & peripodial epithelium | somatic clone | cell non-autonomous‘±Tub84B.PL,capitellum,wing margin bristle,intestinal stem cell,supernumerary,adult midgut precursor cell | late third instar larval stage" FBgn0015946 grim grim http://flybase.org/reports/FBgn0015946 FBgn0064894 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from physical interaction with grim nurse cell apoptotic process ; GO:0045476 | NOT traceable author statement apoptotic process ; GO:0006915 | inferred from direct assay positive regulation of programmed cell death ; GO:0043068 | inferred from mutant phenotype larval central nervous system remodeling ; GO:0035193 | traceable author statement programmed cell death ; GO:0012501 | traceable author statement apoptotic signaling pathway ; GO:0097190 | inferred from genetic interaction with Diap1 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype intrinsic apoptotic signaling pathway in response to osmotic stress ; GO:0008627 | traceable author statement apoptotic process ; GO:0006915 | non-traceable author statement apoptotic process ; GO:0006915 | traceable author statement programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype melanization defense response ; GO:0035006 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:2001272 | inferred from direct assay positive regulation of neuron death ; GO:1901216 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from expression pattern inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "grim, GRIM, Grim, CG4345, BcDNA:RE28551, grm, gri" - CG4345 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | stage >=11 ventral nerve cord | restricted

"decreased cell death,neuroanatomy defective,cell death defective,lethal,lethal - all die before end of pupal stage,some die during pupal stage,visible,size defective,increased cell death,dominant,partially,tarsal response defective,short lived,cell lethal,developmental rate defective,lethal - all die before end of prepupal stage,some die during prepupal stage,recessive,partially lethal - majority die,female semi-fertile,courtship behavior defective,male limited,large body,increased cell number,lethal - all die during larval stage,feeding behavior defective" "peptidergic neuron,ectopic,EW3 neuron,EW3 neuron | prepupal stage,eye,ommatidium,interommatidial bristle,eye disc,wing,mesothoracic tergum,peptidergic neuron | third instar larval stage,EW3 neuron | third instar larval stage,sensory neuron & axon & embryo,peripheral glial cell | embryonic stage,sensory neuron & axon & embryorepo,microchaeta,macrochaeta,embryonic/larval nervous system,embryonic/larval glial cell,segmental nerve pioneer neuron,aCC neuron,sensory neuron,ventral midline,ventral nerve cord,commissure,midline glial cell,embryonic/larval corpus allatum,embryonic/larval fat body | prepupal stage,photoreceptor cell R7 | prepupal stage,photoreceptor cell R8 | prepupal stage,optic lobe | prepupal stage,embryonic/larval salivary gland,fat body,mushroom body,alpha'/beta' Kenyon cell,alpha/beta Kenyon cell,gamma Kenyon cell,prothoracic gland innervating neuron PG-LP,embryonic/larval hemolymph | third instar larval stage,embryonic/larval tracheal system | larval stage,embryonic/larval spiracle | larval stage,glial cell,abdominal neuroblast" FBgn0023095 caps capricious http://flybase.org/reports/FBgn0023095 "FBgn0010789, FBgn0011519, FBgn0064925" protein_coding_gene - "axon guidance ; GO:0007411 | inferred from mutant phenotype larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay cell migration ; GO:0016477 | traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype cell adhesion ; GO:0007155 | non-traceable author statement synapse assembly ; GO:0007416 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype" cytoneme ; GO:0035230 | colocalizes_with inferred from direct assay muscle cell projection ; GO:0036194 | inferred from direct assay "caps, Caps, CAPS, CG11282, CT31495, l(3)02937, l(3)rM632, BcDNA:LD07388, capricious" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG11282 11-Aug-17 DroID_v2017_08 "Drer\lrfn2b, Drer\flrt1a, Drer\lingo4b, Drer\lrrn1, Drer\lrfn1, Drer\flrt3, Drer\lrrc15, Drer\si:ch211-180f4.1, Drer\lrfn5a, Drer\lingo2a, Drer\LOC100535105, Drer\lrrn3, Drer\zmp:0000001073, Drer\lrrn2, Drer\lrfn4b, Drer\zgc:172282, Drer\lrfn5b, Drer\flrt1b, Drer\lrfn4a" - "Cele\let-4, Cele\tbce-1, Cele\sma-10, Cele\dma-1" "Xtro\lrfn2, Xtro\lrfn5, Xtro\lrfn3, Xtro\lrfn1, Xtro\tril, Xtro\lrrn3, Xtro\flrt1, Xtro\flrt3, Xtro\LOC100488097, Xtro\lrrn1, Xtro\lrrn1-like" "Mmus\Lrfn3, Mmus\Lrfn5, Mmus\Flrt3, Mmus\Lingo2, Mmus\Tril, Mmus\Lrrtm1, Mmus\Lrrn1, Mmus\Lrrtm2, Mmus\Lrrn2, Mmus\Flrt1, Mmus\Lrfn4, Mmus\Lrrn3, Mmus\Lrfn2, Mmus\Lrfn1" "Hsap\LRRN2, Hsap\LRRN3, Hsap\LRFN5, Hsap\LRRTM1, Hsap\FLRT3, Hsap\LRRC70, Hsap\LRFN4, Hsap\LINGO2, Hsap\LRFN1, Hsap\LRRN1, Hsap\LRFN2, Hsap\FLRT1, Hsap\LRFN3" embryonic stage " abdominal dorsal acute muscle 1

, abdominal dorsal oblique muscle 2

, RP5 neuron

, abdominal ventral oblique muscle 6

, RP2 neuron

, abdominal ventral oblique muscle 5

, abdominal ventral oblique muscle 4

, abdominal dorsal oblique muscle 1

, abdominal ventral longitudinal muscle 1

, aCC neuron

, abdominal ventral oblique muscle 3

, U neuron

, abdominal dorsal acute muscle 2

, abdominal ventral oblique muscle 1

" " larval stage | third instar , embryonic stage , larval stage | first instar " " dorsal mesothoracic disc | dorsal comparment & lateral

, neuron

, synapse

" "lethal,recessive,neuroanatomy defective,somatic clone,viable,fertile,visible" "embryonic/larval salivary gland,photoreceptor cell R8,somatic clone,macrochaeta,A1-7 ventral motor neuron,axon,dorsal trunk primordium,motor neuron,motor neuron | third instar larval stage,dendriteMz19,projection neuron,abdominal anterior fascicle & synapse,intersegmental nerve branch ISNb of A1-7,eye photoreceptor cell,motor neuron | embryonic stage,air sac primordium | third instar larval stage,photoreceptor cell R7,wing disc,dorsal/ventral compartment boundary,ventral compartment,abdominal ventral longitudinal muscle 2 & synapseG14,synapse | ectopicG14,abdominal anterior fascicle & synapseG14,abdominal ventral longitudinal muscle 2 & synapsel(3)H94-H94,synapse | ectopicl(3)H94-H94,abdominal anterior fascicle & synapsel(3)H94-H94,transverse nerve,lateral trunk primordium,antennal lobe,dendrite | somatic cloneunspecified,antennal lobe projection neuron,adult antennal lobe projection neuron DL1 adPN,dendrite | somatic cloneGH146,leg,ventral thoracic disc,antennal lobe projection neuron lPN,dendrite | somatic clone,adult antennal lobe projection neuron DM1 lPN,adult antennal lobe projection neuron VA4 lPN,adult antennal lobe projection neuron VC2 lPN,pretarsus,adult antennal lobe projection neuron VC1 lPN,chaeta,trichogen cell,supernumerary" FBgn0010397 LamC Lamin C http://flybase.org/reports/FBgn0010397 FBgn0010037 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from mutant phenotype muscle tissue morphogenesis ; GO:0060415 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from direct assay tendon development ; GO:0035989 | inferred from mutant phenotype nuclear pore distribution ; GO:0031081 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype lamin filament ; GO:0005638 | non-traceable author statement lamin filament ; GO:0005638 | inferred from direct assay spindle envelope ; GO:0070732 | inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay nuclear envelope ; GO:0005635 | colocalizes_with inferred from direct assay nuclear periphery ; GO:0034399 | inferred from direct assay "LAMC, pG-IF, lamC, G-IF, CG10119, LamC, DmC" "IPR001322:Lamin Tail Domain, IPR001664:Intermediate filament protein" CG10119 11-Aug-17 DroID_v2017_08 "Drer\gfap, Drer\zgc:171226, Drer\desmb, Drer\cyt1, Drer\iffo1a, Drer\krt97, Drer\ngs, Drer\desma, Drer\zgc:172323, Drer\nefma, Drer\lmnb1, Drer\inaa, Drer\neflb, Drer\zgc:77517, Drer\vim, Drer\viml, Drer\krt8, Drer\krt4, Drer\si:dkey-222n6.2, Drer\lmna, Drer\zgc:65851, Drer\iffo2a, Drer\krt5, Drer\nefla, Drer\krt18, Drer\krt15, Drer\nefmb, Drer\lmnb2, Drer\krt91, Drer\lmnl3, Drer\prph, Drer\inab" - "Cele\ifa-3, Cele\ifd-2, Cele\ifd-1, Cele\ifc-1, Cele\ifb-1, Cele\ifa-4, Cele\mua-6, Cele\ifc-2, Cele\F10C1.8, Cele\ifa-1, Cele\ifb-2, Cele\ifp-1, Cele\lmn-1" "Xtro\krt5.3, Xtro\krt8.2, Xtro\lmna, Xtro\nif, Xtro\krt19, Xtro\krt17, Xtro\vim, Xtro\vim.2, Xtro\krt5.2, Xtro\nefl, Xtro\krt8, Xtro\krt18, Xtro\krt5.7, Xtro\prph, Xtro\krt, Xtro\lmnb1, Xtro\ina, Xtro\lmnb3, Xtro\iffo2, Xtro\lmnb2, Xtro\des.1" "Mmus\Krt79, Mmus\Krt15, Mmus\Lmnb2, Mmus\Krt90, Mmus\Krt73, Mmus\Krt17, Mmus\Lmna, Mmus\Krt35, Mmus\Krt19, Mmus\Des, Mmus\Ina, Mmus\Gfap, Mmus\Iffo1, Mmus\Nefl, Mmus\Lmntd1, Mmus\Lmnb1, Mmus\Krt1, Mmus\Vim, Mmus\Krt13, Mmus\Krt6b, Mmus\Krt71, Mmus\Lmntd2, Mmus\Krt5, Mmus\Iffo2, Mmus\Krt75, Mmus\Nefm, Mmus\Krt42, Mmus\Krt7, Mmus\Krt8, Mmus\Krt6a, Mmus\Krt14, Mmus\Krt36, Mmus\Krt16, Mmus\Prph" "Hsap\KRT5, Hsap\PRPH, Hsap\KRT74, Hsap\VIM, Hsap\KRT84, Hsap\KRT7, Hsap\NEFM, Hsap\KRT6B, Hsap\KRT76, Hsap\KRT1, Hsap\INA, Hsap\NEFH, Hsap\KRT23, Hsap\KRT80, Hsap\KRT71, Hsap\KRT6C, Hsap\KRT3, Hsap\KRT33A, Hsap\KRT15, Hsap\KRT33B, Hsap\LMNTD1, Hsap\KRT13, Hsap\KRT79, Hsap\GFAP, Hsap\LMNTD2, Hsap\KRT73, Hsap\KRT10, Hsap\LOC100653049, Hsap\KRT8, Hsap\KRT19, Hsap\KRT14, Hsap\NEFL, Hsap\IFFO2, Hsap\IFFO1, Hsap\DES, Hsap\KRT12, Hsap\LMNB1, Hsap\KRT9, Hsap\KRT75, Hsap\LMNA, Hsap\LMNB2, Hsap\KRT35, Hsap\KRT31, Hsap\KRT16, Hsap\KRT4, Hsap\KRT17" " embryonic stage | >=12 hr , embryonic stage | stage 13 , embryonic stage | stage 12 , larval stage--adult stage " " embryonic/larval dorsal trunk

, oenocyte

, embryonic/larval foregut

, embryonic/larval hindgut

" " embryonic stage | >=12-15 hr , embryonic stage | stage 15 , embryonic stage | stage 12 , larval stage , embryonic stage | stage 16 , embryonic stage | stage 12 | late , larval stage--adult stage , adult stage " " epidermis

, embryonic/larval foregut

, embryonic/larval dorsal trunk

, posterior spiracle primordium

, exit glial cell

, inclusive hindgut primordium

, oenocyte

, dorsal prothoracic pharyngeal muscle

, interfollicle cell

, visceral mesoderm

, germarium cap cell

" "lethal - all die before end of P-stage,some die during P-stage,viable,partially lethal - majority die,locomotor behavior defective,lethal,lethal - all die before end of first instar larval stage,increased cell death,partially lethal - majority live,visible,temperature conditional,recessive,heat sensitive,melanotic mass phenotype,lethal - all die before end of prepupal stage,some die during prepupal stage,some die during third instar larval stage,suppressor of variegation,dominant,developmental rate defective,body color defective,some die during pupal stage" "tendon cell,leg,pupa,nucleusUbx-lac1-Gal4,longitudinal muscle | first instar larval stage,indirect flight muscle,nucleusptc-559.1,anterior-posterior boundary of the wing disc | third instar larval stage,wing blade,scutellum,thorax,mesothoracic bristle,wing vein,somatic muscle | P-stage,tendon cell | larval stage,tendon cell | P-stage,embryonic/larval salivary gland,melanotic mass,heat sensitive,larval salivary gland & embryo & nucleus | conditional ts,imaginal disc,nuclear inner membrane | larval stage,nuclear outer membrane | larval stage,nuclear envelope | larval stage,nuclear pore | larval stage,nucleus | larval stage,mesothoracic tergum,nucleusC57,embryonic/larval somatic muscle,metathoracic femur,metathoracic tibia,metathoracic tarsal segment,ventral thoracic disc,metathoracic metatarsus" FBgn0016917 Stat92E Signal-transducer and activator of transcription protein at 92E http://flybase.org/reports/FBgn0016917 "FBgn0010885, FBgn0011396, FBgn0015512" protein_coding_gene "signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR001217, InterPro:IPR012345, InterPro:IPR013799, InterPro:IPR013800, InterPro:IPR013801, InterPro:IPR015988 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement DNA binding ; GO:0003677 | inferred from sequence or structural similarity with HGNC:11366 inferred from sequence or structural similarity with HGNC:11368 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Cdk2 inferred from physical interaction with Cdk4" "regulation of transcription, DNA-templated ; GO:0006355 |... electronic annotation with InterPro:IPR001217, InterPro:IPR008967, InterPro:IPR012345, InterPro:IPR013799, InterPro:IPR013800, InterPro:IPR013801, InterPro:IPR015988 <> stem cell division ; GO:0017145 |... mutant phenotype <> negative regulation of antimicrobial humoral response ; GO:0008348 |... mutant phenotype inferred from genetic interaction with Rel <> oogenesis ; GO:0048477 |... mutant phenotype <> border follicle cell migration ; GO:0007298 | traceable author statement <> positive regulation of defense response to virus by host ; GO:0002230 |... mutant phenotype <> humoral immune response ; GO:0006959 | traceable author statement <> JAK-STAT cascade ; GO:0007259 | traceable author statement <> blastoderm segmentation ; GO:0007350 |... mutant phenotype <> border follicle cell migration ; GO:0007298 |... mutant phenotype <> cell dedifferentiation ; GO:0043697 |... expression pattern <> germ-line stem cell division ; GO:0042078 | traceable author statement <> compound eye development ; GO:0048749 | traceable author statement <> sex determination ; GO:0007530 | non-traceable author statement <> defense response ; GO:0006952 |... direct assay <> positive regulation of cell proliferation ; GO:0008284 |... mutant phenotype <> oogenesis ; GO:0048477 | traceable author statement <> lamellocyte differentiation ; GO:0035171 | non-traceable author statement <> cellular response to lipopolysaccharide ; GO:0071222 |... direct assay <> nervous system development ; GO:0007399 |... mutant phenotype <> epithelial cell fate determination, open tracheal system ; GO:0007425 | traceable author statement <> cellular response to X-ray ; GO:0071481 |... mutant phenotype <> somatic stem cell division ; GO:0048103 | traceable author statement <> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <> larval lymph gland hemopoiesis ; GO:0035167 |... mutant phenotype <> larval lymph gland hemopoiesis ; GO:0035167 |... genetic interaction with bip1 <> larval somatic muscle development ; GO:0007526 |... mutant phenotype <> hindgut morphogenesis ; GO:0007442 |... mutant phenotype <> hemopoiesis ; GO:0030097 | non-traceable author statement <> negative regulation of stem cell differentiation ; GO:2000737 |... mutant phenotype <> lamellocyte differentiation ; GO:0035171 | traceable author statement <> eye-antennal disc morphogenesis ; GO:0007455 |... mutant phenotype <> ovarian follicle cell stalk formation ; GO:0030713 |... mutant phenotype <> somatic stem cell population maintenance ; GO:0035019 |... mutant phenotype <> oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 |... mutant phenotype <> hemocyte proliferation ; GO:0035172 | traceable author statement <> segment specification ; GO:0007379 |... mutant phenotype <> regulation of JAK-STAT cascade ; GO:0046425 |... mutant phenotype <> primary sex determination ; GO:0007538 |... mutant phenotype <> open tracheal system development ; GO:0007424 |... mutant phenotype <> stem cell population maintenance ; GO:0019827 |... mutant phenotype <> negative regulation of Wnt signaling pathway ; GO:0030178 |... mutant phenotype <> long-term memory ; GO:0007616 |... mutant phenotype <> germ-line stem cell population maintenance ; GO:0030718 |... mutant phenotype" nucleus ; GO:0005634 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "stat92E, STAT92E, Stat92E, dSTAT, STAT, stat, Dstat, Stat, DmSTAT, mrl, D-STAT, mrL, D-stat, D-stat/stat92E, D-Stat, dSTAT92E/marelle, STAT 92E, SD-stat, DSRC, DRODSRC, mrl stat92E, DSTAT, Dstat92E, Dstat 92E, l(3)06346, d-STAT, Stat1alpha-like, dSTAT92E, l(3)j6C8, CG4257, pSTAT, Stat92, stat92e, stat92, dstat, stat[92E], STAT92e, Stat92e" "IPR015988:STAT transcription factor, coiled coil, IPR000980:SH2 domain, IPR001217:Transcription factor STAT, IPR008967:p53-like transcription factor, DNA-binding, IPR012345:STAT transcription factor, DNA-binding, subdomain, IPR013799:STAT transcription factor, protein interaction, IPR013800:STAT transcription factor, all-alpha domain, IPR013801:STAT transcription factor, DNA-binding" CG4257 11-Aug-17 DroID_v2017_08 "Drer\stat1b, Drer\stat2, Drer\stat5b, Drer\stat5a, Drer\stat3, Drer\stat1a, Drer\stat6, Drer\stat4" - "Cele\sta-1, Cele\sta-2" "Xtro\stat3.1, Xtro\stat5b, Xtro\stat4, Xtro\stat2, Xtro\stat1, Xtro\stat6" "Mmus\Stat3, Mmus\Stat1, Mmus\Stat6, Mmus\Stat5b, Mmus\Stat4, Mmus\Stat5a, Mmus\Stat2" "Hsap\STAT5A, Hsap\STAT3, Hsap\STAT5B, Hsap\STAT2, Hsap\STAT4, Hsap\STAT6, Hsap\STAT1" " embryonic stage | 1 hr , embryonic stage | early , embryonic stage | stage 15 , embryonic stage | extended germ band , embryonic stage -- adult stage , embryonic stage | 1-3 hr " "

ubiquitous , embryonic/larval foregut

, gonad | precursor

, embryonic/larval hindgut

, organism | segment polarity

, mesoderm

,

pair rule " oogenesis stage | stage S5-7 " nurse follicle cell

, centripetally migrating follicle cell

, border follicle cell

, polar follicle cell

" "small body,lethal,heat sensitive,memory defective,RU486 conditional,visible,viable,fertile,recessive,female sterile,male sterile,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,maternal effect,rescuable maternal effect,wild-type,somatic clone,partially,germline clone,melanotic mass phenotype,lethal - all die before end of embryonic stage,some die during embryonic stage,planar polarity defective,dominant,pair rule phenotype,hyperplasia,increased cell death,conditional,stress response defective,partially lethal - majority die" "embryonic/larval somatic muscle,germline clone,wing,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic head,wing vein,ectopic,eye,somatic clone,antenna,follicle cell,polar follicle cell,oocyte,egg chamber,interfollicle cell,anterior,cell autonomous,male germline stem cell,germarium,cell non-autonomous,ovarian basement membrane,ovarian sheath cell,spectrosome | cell non-autonomous | somatic clone,cyst progenitor cell,male,spermatogonium,heat sensitive,spermatocyte,cyst cell,tracheal pit,border follicle cell,dorsal appendage,embryonic/larval anterior spiracle,spermathecum,supernumerary,leg,adult cuticle,germline stem cell,escort cell,escort stem cell,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,mesothoracic ventral denticle belt,non-rescuable maternal effect,presumptive embryonic/larval tracheal system,embryonic/larval proventriculus,embryonic hindgut,nurse follicle cell,pole cell,maternal effect,gonad,telson,segment,ovariole,embryonic/first instar larval cuticle,mesothoracic segment,abdominal segment 5,abdominal segment 8,filzkorper,embryonic/larval posterior spiracle,embryonic segment,embryonic/larval tracheal system,tracheal system,hindgut,hindgut & nucleus,central nervous system,commissure,longitudinal connective,peripheral nervous system,axon,denticle belt,rescuable maternal effect,germline cell,ectoderm,melanotic mass,larval optic anlage,embryonic abdominal segment,ommatidium,adult segment,trachea,epidermis,posterior compartment,embryonic/larval lymph gland,plasmatocyte,wing disc,conditional,cuticle & adult external head | somatic clone,head,eye disc,morphogenetic furrow,imaginal disc,dorsal prothorax,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,posterior spiracle primordium,tracheal branch primordium,mouth hooks,trichogen cell,mesothoracic tergum,midgut" DRSC16870 IE 0.899886427 2.078730627 -0.835424245 1.885027711 1.0967906 1.182478138 FBgn0020306 dom domino http://flybase.org/reports/FBgn0020306 "FBgn0022058, FBgn0024590, FBgn0034621, FBgn0046413" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 DNA-dependent ATPase activity ; GO:0008094 | inferred from sequence or structural similarity with brm inferred from sequence or structural similarity with HGNC:11100 protein binding ; GO:0005515 | inferred from physical interaction with E2f1 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay "wing disc pattern formation ; GO:0035222 | inferred from genetic interaction with mam inferred from genetic interaction with N oogenesis ; GO:0048477 | inferred from mutant phenotype positive regulation of gene silencing by miRNA ; GO:2000637 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from direct assay hemopoiesis ; GO:0030097 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype histone exchange ; GO:0043486 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with mam inferred from genetic interaction with N somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype negative regulation of hemocyte proliferation ; GO:0035207 | traceable author statement gene silencing ; GO:0016458 | inferred from genetic interaction with brm inferred from genetic interaction with E(z) inferred from genetic interaction with Pc inferred from genetic interaction with trx inferred from genetic interaction with ph-p inferred from genetic interaction with ash1 inferred from genetic interaction with mxc regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype histone exchange ; GO:0043486 | inferred from direct assay negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype" histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 "CG9696, DomA, 27/4, l(2)81/8, l(2)k08108, l(2)k02704, anon-WO0172774.190, dom, Domino, Dom, p400, DOM, DOM-A, dEP400" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014012:Helicase/SANT-associated domain, IPR017877:Myb-like domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9696 11-Aug-17 DroID_v2017_08 "Drer\ep400, Drer\srcap" Scer\SWR1 Cele\ssl-1 Xtro\ep400 "Mmus\Ep400, Mmus\Tmem265, Mmus\Srcap" "Hsap\SRCAP, Hsap\EP400" "visible,neuroanatomy defective,viable,fertile,lethal,recessive,cell lethalcell lethal,somatic clone,female sterile,germline clone,immune response defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,male fertile,suppressor of variegation,dominant,partially lethal - majority live,maternal effect,lethal - all die before end of larval stage,some die during larval stage,decreased cell number" "wing margin,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,embryonic/larval lymph gland,hemocyte,imaginal disc,prohemocyte,imaginal ring,midgut imaginal island,embryonic/larval hemocyte,plasmatocyte,follicle stem cell,somatic clone,neuroblast,wing,anterior crossvein,ocellus,head bristle,mesothoracic tergum,tarsal segment,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,adult antennal lobe projection neuron DL1 adPN" DRSC04558 IE -1.426581268 -3.400750336 -0.155421592 -2.794748799 -0.400066297 -0.097519241 FBgn0003130 Poxn Pox neuro http://flybase.org/reports/FBgn0003130 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001523, InterPro:IPR009057" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001523 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype response to water ; GO:0009415 | inferred from direct assay imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype adult feeding behavior ; GO:0008343 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "poxn, Pox-n, neuro, pox-n, P4, CG8246, Poxn" "IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG8246 11-Aug-17 DroID_v2017_08 "Drer\pax8, Drer\arxa, Drer\pax7a, Drer\pax6b, Drer\pax5, Drer\pax10, Drer\pax3a, Drer\pax6a, Drer\pax2b, Drer\pax2a, Drer\pax1b, Drer\pax9, Drer\pax1a, Drer\arxb, Drer\pax7b" - "Cele\pax-1, Cele\vab-3, Cele\alr-1, Cele\pax-2, Cele\egl-38" "Xtro\pax9, Xtro\pax3, Xtro\pax7, Xtro\pax6, Xtro\pax5, Xtro\pax8, Xtro\arx, Xtro\pax2, Xtro\pax1" "Mmus\Pax8, Mmus\Pax9, Mmus\Pax2, Mmus\Pax7, Mmus\Pax1, Mmus\Pax6, Mmus\Pax5, Mmus\Pax3, Mmus\Arx, Mmus\Pax4" "Hsap\PAX2, Hsap\PAX8, Hsap\PAX1, Hsap\PAX3, Hsap\ARX, Hsap\PAX4, Hsap\PAX5, Hsap\PAX6, Hsap\PAX7, Hsap\PAX9" embryonic stage " embryonic peripheral nervous system | restricted

, central nervous system | restricted

" " embryonic stage , prepupal stage | stage P1 , larval stage | third instar , embryonic stage | mid , embryonic stage | stage 11-13 " " Kolbchen | lateral metathoracic segment

, embryonic peripheral nervous system | restricted

, embryonic peripheral nervous system | segmentally repeated pattern

, organism

, central nervous system | restricted

, wing margin bristle | precursor | restricted

, ganglion mother cell

, central nervous system | segmentally repeated

, neuroblast

, Kolbchen | lateral mesothoracic segment

" "courtship behavior defective,male,lethal,recessive,visible,feeding behavior defective,viable,male sterile,mating defective,flight defective,taste perception defective,proboscis extension reflex defective" "wing vein L3,wing vein,wing vein L3 & macrochaeta,macrochaeta,ectopic,mechanosensory sensory organ & tibia & adult,mechanosensory sensory organ & tibia & neuron & adult,chemosensory sensory organ,mechanosensory sensory organ,chordotonal organ,external sensory organ,eye,Kolbchen,ommatidium,cone cell,dorsal triple row,chemosensory ventral triple row bristle,mesothoracic leg sensillum & tibia,mesothoracic leg taste bristle,metathoracic leg taste bristle,prothoracic leg taste bristle,labellar taste bristle,mechanosensory chaeta,penis,posterior lobe,clasper,wing hinge,adult brain,taste bristle,prothoracic ventral Kolbchen vbd,mesothoracic lateral Kolbchen lbd,mesothoracic ventral Kolbchen vbd,metathoracic lateral Kolbchen lbd,metathoracic ventral Kolbchen vbd,larval thoracic segment & sensillum campaniformium | ectopic,abdominal dorsal sensillum trichodeum dh1,larval abdominal segment & sensillum campaniformium | ectopic,larval abdominal segment & sensillum trichodeum | ectopic,mesothoracic les3 neuron,metathoracic les3 neuron,mesothoracic v'es3 neuron,metathoracic v'es3 neuron,des2 neuron,abdominal 1 v'es2 neuron,abdominal 2 v'es2 neuron,abdominal 3 v'es2 neuron,abdominal 4 v'es2 neuron,abdominal 5 v'es2 neuron,abdominal 6 v'es2 neuron,abdominal 7 v'es2 neuron,sensillum trichodeum,sensillum campaniformium,mesothoracic metatarsus,mesothoracic tarsal segment 2,mesothoracic tarsal segment 3,mesothoracic tarsal segment 4,mesothoracic tarsal segment 5,mesothoracic tarsal segment & joint,basal cylinder,arista,wing hinge & wing vein,wing hinge & wing vein L5,sensory mother cell,adult head,antenna" FBgn0085351 inaF-A inaF-A http://flybase.org/reports/FBgn0085351 protein_coding_gene channel regulator activity ; GO:0016247 | inferred from sequence or structural similarity with inaF-B regulation of membrane potential ; GO:0042391 | inferred from sequence or structural similarity with inaF-B membrane ; GO:0016020 | inferred from sequence or structural similarity with inaF-B "inaF-A, CG34322, inaF, INAF, InaF, Dm_X:58729" "IPR029162:TRP-interacting helix, InaF motif" CG34322 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0264501 CR43900 - http://flybase.org/reports/FBgn0264501 non_protein_coding_gene - - - CR43900 - CR43900 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0036078 Or67c Odorant receptor 67c http://flybase.org/reports/FBgn0036078 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from direct assay "67c, DOR77, 67D.1, CG14156, Or67c, DmOR67C" "IPR004117:Olfactory receptor, insect" CG14156 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0003317 sax saxophone http://flybase.org/reports/FBgn0003317 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000333, InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR003605, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from electronic annotation with InterPro:IPR000333 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR017194 transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Dad protein kinase activity ; GO:0004672 | non-traceable author statement transforming growth factor beta receptor activity, type I ; GO:0005025 | non-traceable author statement transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from sequence or structural similarity with MGI:MGI:87911" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR002290, InterPro:IPR003605, InterPro:IPR008271 decapentaplegic signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | traceable author statement ovarian follicle cell development ; GO:0030707 | traceable author statement chorion-containing eggshell formation ; GO:0007304 | inferred from genetic interaction with tkv transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from sequence or structural similarity germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement negative regulation of BMP signaling pathway ; GO:0030514 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype inferred from genetic interaction with dpp negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype anterior/posterior pattern specification, imaginal disc ; GO:0007448 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype decapentaplegic signaling pathway ; GO:0008101 | inferred from mutant phenotype inferred from genetic interaction with dpp compound eye morphogenesis ; GO:0001745 | non-traceable author statement wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from direct assay inferred from genetic interaction with dpp BMP signaling pathway ; GO:0030509 | traceable author statement maternal determination of anterior/posterior axis, embryo ; GO:0008358 | inferred from mutant phenotype maternal determination of anterior/posterior axis, embryo ; GO:0008358 | inferred from genetic interaction with dpp" receptor complex ; GO:0043235 | inferred from electronic annotation with InterPro:IPR017194 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with MGI:MGI:87911 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with MGI:MGI:87911 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "CG1891, sax, Sax, Bkr43E, Brk43E, STK-B, SAX, Sa" "IPR000472:Activin types I and II receptor domain, IPR000719:Protein kinase domain, IPR003605:GS domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017194:Transforming growth factor-beta receptor, type II, IPR000333:Ser/Thr protein kinase, TGFB receptor, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG1891 11-Aug-17 DroID_v2017_08 "Drer\tgfbr1b, Drer\acvr1bb, Drer\acvrl1, Drer\acvr1l, Drer\bmpr1aa, Drer\bmpr1ab, Drer\bmpr1ba, Drer\tgfbr1a, Drer\LOC100331105, Drer\acvr1ba" - "Cele\daf-1, Cele\sma-6" "Xtro\acvr1c, Xtro\tgfbr1, Xtro\bmpr1b, Xtro\acvr1, Xtro\acvr1b, Xtro\bmpr1a" "Mmus\Acvrl1, Mmus\Acvr1b, Mmus\Tgfbr1, Mmus\Acvr1c, Mmus\Acvr1, Mmus\Bmpr1a, Mmus\Bmpr1b" "Hsap\ACVR1B, Hsap\TGFBR1, Hsap\BMPR1B, Hsap\ACVR1, Hsap\BMPR1A, Hsap\ACVR1C, Hsap\ACVRL1" " embryonic stage -- adult stage , embryonic stage "

ubiquitous "viable,lethal,developmental rate defective,size defective,partially lethal - majority die,maternal effect,visible,dominant,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,wild-type,female sterile,neurophysiology defective,somatic clone,neuroanatomy defective,circadian rhythm defective" "imaginal disc,brain,trachea,germarium,female germline stem cell,amnioserosa,maternal effect,midgut constriction 2,anterior crossvein,eye,ommatidium,wing,wing vein,ectopic,egg,ovary,egg chamber,extended germ band embryo,cephalic furrow,embryonic head,filzkorper,abdominal segment 7,abdominal segment 8,embryonic/larval epidermis,dorsal,embryonic/larval midgut,embryonic/first instar larval cuticle,amnioproctodeal invagination,dorsal appendage,germline clone,wing vein L4,somatic clone,2nd posterior cell,dil cell,wing basal cell 2,fat body,neuromuscular junctionsax-H9),bouton,neuromuscular junctioncn7969),triple row,distal costal vein,dorsal double row,ventral double row,male germline stem cell,cell non-autonomous,trichome of the posterior wing margin,ovariole,synapse,t-bar,embryonic/larval dorsal branch,wing disc,wing vein L5,posterior crossvein,wing vein L2,dorsal triple row,proximal,medial triple row,ventral triple row,wing blade,posterior,wing cell,embryonic/larval tracheal system,trichogen cell,supernumerary" DRSC26844 K 0.401438369 0.01057449 0.394041202 0.198949049 -1.515195925 -1.309782523 FBgn0003651 svp seven up http://flybase.org/reports/FBgn0003651 "FBgn0011337, FBgn0011492, FBgn0011510, FBgn0038010, FBgn0063263" protein_coding_gene "RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | inferred from electronic annotation with InterPro:IPR003068 steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR001723 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with svp protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with EcR RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay receptor activity ; GO:0004872 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with rig" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR003068, InterPro:IPR013088 steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 ventral cord development ; GO:0007419 | traceable author statement compound eye photoreceptor fate commitment ; GO:0001752 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype epithelial cell proliferation involved in Malpighian tubule morphogenesis ; GO:0061331 | inferred from mutant phenotype R7 cell fate commitment ; GO:0007465 | traceable author statement R1/R6 cell fate commitment ; GO:0007462 | traceable author statement glial cell development ; GO:0021782 | inferred from mutant phenotype neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype cardioblast cell fate determination ; GO:0007510 | inferred from expression pattern inferred from genetic interaction with tin fat body development ; GO:0007503 | traceable author statement heart development ; GO:0007507 | non-traceable author statement heart development ; GO:0007507 | traceable author statement photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR003068 cytoplasm ; GO:0005737 | inferred from direct assay" "svp, NR2F3, CG18158, Svp, don, 0861/07, 0598/01, 0351/01, 0114/20, 0106/18, 0042/01, 0005/12, SVP, ck16, l(3)ck16, l(3)rL069, l(3)rA028, l(3)j2E2, l(3)87Bd, l(3)07842, CG11502, BcDNA:GH08189, SVP1, SVP-1" "IPR013088:Zinc finger, NHR/GATA-type, IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR003068:Transcription factor COUP" CG11502 11-Aug-17 DroID_v2017_08 "Drer\nr2c1, Drer\rxrbb, Drer\nr0b2a, Drer\esrra, Drer\nr1h4, Drer\rxrab, Drer\esr2b, Drer\rxrba, Drer\nr2e1, Drer\esrrga, Drer\nr1i2, Drer\esr2a, Drer\nr6a1b, Drer\nr2f5, Drer\thrab, Drer\rxraa, Drer\nr2e3, Drer\nr2f6b, Drer\nr5a1a, Drer\ar, Drer\nr2f1b, Drer\nr1h5, Drer\nr2f6a, Drer\esr1, Drer\pparab, Drer\vdra, Drer\pparg, Drer\rxrga, Drer\nr2f1a, Drer\nr3c1, Drer\raraa, Drer\pgr, Drer\ppardb, Drer\rargb, Drer\nr2c2, Drer\esrrd, Drer\pparaa, Drer\vdrb, Drer\nr2f2, Drer\nr0b2b, Drer\nr0b1, Drer\rarab, Drer\pparda" - "Cele\nhr-107, Cele\nhr-79, Cele\nhr-11, Cele\nhr-46, Cele\nhr-256, Cele\unc-55, Cele\nhr-277" "Xtro\nr1h2, Xtro\nr2c2, Xtro\nr6a1, Xtro\rara, Xtro\nr0b2, Xtro\nr0b1, Xtro\esrrgr, Xtro\nr1i2, Xtro\esrrg, Xtro\rxrb, Xtro\rxrg, Xtro\nr3c1, Xtro\esrrb, Xtro\nr2f1, Xtro\nr2f6, Xtro\nr2c1, Xtro\pparg, Xtro\esr1, Xtro\nr3c2, Xtro\nr2f2, Xtro\thrb, Xtro\vdr, Xtro\nr2f5, Xtro\ppard, Xtro\esrra, Xtro\rxra, Xtro\esr2, Xtro\nr2e3, Xtro\rarg, Xtro\pgr, Xtro\nr2e1, Xtro\nr1h5, Xtro\ppara, Xtro\ar, Xtro\rarb" "Mmus\Nr1h3, Mmus\Rxra, Mmus\Nr2e1, Mmus\Rxrb, Mmus\Esrrb, Mmus\Esrrg, Mmus\Thra, Mmus\Nr3c2, Mmus\Nr2e3, Mmus\Vdr, Mmus\Rara, Mmus\Nr3c1, Mmus\Esr1, Mmus\Rxrg, Mmus\Nr1h4, Mmus\Nr2f2, Mmus\Pparg, Mmus\Nr1h2, Mmus\Ar, Mmus\Ppara, Mmus\Rarb, Mmus\Esrra, Mmus\Thrb, Mmus\Rarg, Mmus\Nr0b1, Mmus\Nr0b2, Mmus\Nr1i3, Mmus\Pgr, Mmus\Nr6a1, Mmus\Nr2c2, Mmus\Nr1i2, Mmus\Nr2c1, Mmus\Esr2, Mmus\Ppard, Mmus\Nr2f1, Mmus\Nr2f6, Mmus\Nr1h5" "Hsap\NR0B1, Hsap\NR2C1, Hsap\PPARG, Hsap\ESRRG, Hsap\NR0B2, Hsap\RARG, Hsap\AR, Hsap\ESRRB, Hsap\NR2C2, Hsap\NR3C1, Hsap\NR3C2, Hsap\NR1H2, Hsap\THRB, Hsap\RXRA, Hsap\NR1H3, Hsap\RARA, Hsap\NR1I2, Hsap\NR2F2, Hsap\NR6A1, Hsap\RARB, Hsap\NR2E1, Hsap\NR1I3, Hsap\RXRG, Hsap\NR2F1, Hsap\NR1H4, Hsap\ESRRA, Hsap\RXRB, Hsap\ESR2, Hsap\PPARA, Hsap\ESR1, Hsap\THRA, Hsap\PPARD, Hsap\NR2F6, Hsap\VDR, Hsap\PGR" " larval stage , embryonic stage | stage >=11 , embryonic stage | stage >=10 " " photoreceptor cell R4 | precursor

, morphogenetic furrow | posterior to

, Malpighian tubule tip cell

, Malpighian tubule | restricted

, photoreceptor cell R6 | precursor

, photoreceptor cell R3 | precursor

, photoreceptor cell R1 | precursor

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,planar polarity defective,somatic clone,visible,heat sensitive,uncoordinated,dominant,neuroanatomy defective,neurophysiology defective,phototaxis defective,viable,fertile,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal - all die during larval stage" "ommatidium,somatic clone,photoreceptor cell R1,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R6,precursor,macrochaeta,embryonic/larval oenocyte,photoreceptor cell R7,cone cell,eye,eye photoreceptor cell,heat sensitive,embryonic/larval ostia,U1 neuron,supernumerary,U4 neuron,U5 neuron,EW1 neuron,GW neuron,EW2 neuron,EW3 neuron,Malpighian tubule,outer photoreceptor cell,inner photoreceptor cell,ectopic,6-4Ic,6-4Ii,neuroblast NB6-4 of thorax,photoreceptor cell R2 & axon,photoreceptor cell R5 & axon,embryonic posterior Malpighian tubule,embryonic anterior Malpighian tubule,FMRFamide SE2 neuron,mystery cell,photoreceptor cell R8,photoreceptor cell & axon | somatic clone,lamina,medulla,dorsal closure embryo,U neuron,EW neuron,embryonic/larval optic stalk surface glial cell | third instar larval stage" DRSC17075 I 0.793767781 1.641326499 0.745384682 0.867669482 -0.465455488 0.021712991 FBgn0002962 nos nanos http://flybase.org/reports/FBgn0002962 "FBgn0010916, FBgn0011347, FBgn0011364, FBgn0026836" protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR008705 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR008705 protein binding ; GO:0005515 | inferred from physical interaction with cup protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MQJ9" "germ-line stem cell population maintenance ; GO:0030718 | inferred from direct assay negative regulation of translation ; GO:0017148 | non-traceable author statement negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with hid negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement oocyte anterior/posterior axis specification ; GO:0007314 | non-traceable author statement female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement negative regulation of translation ; GO:0017148 | traceable author statement germ-line stem cell division ; GO:0042078 | non-traceable author statement pole cell migration ; GO:0007280 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | traceable author statement spermatogenesis ; GO:0007283 | inferred from mutant phenotype" neuromuscular junction ; GO:0031594 | inferred from direct assay pole plasm ; GO:0045495 | traceable author statement postsynapse of neuromuscular junction ; GO:0098975 | inferred from mutant phenotype "nos, DRONANOS, NANOS, l(3)j3B6, nNOS, l(3)j4B6, l(3)07117, CG5637, NOS, Nos, Dronanos, nanos, Nanos" "IPR008705:Nanos/Xcat2, IPR024161:Zinc finger, nanos-type" CG5637 11-Aug-17 DroID_v2017_08 "Drer\nanos3, Drer\nanos1" - "Cele\nos-2, Cele\nos-1" Xtro\nanos1 "Mmus\Nanos2, Mmus\Nanos3, Mmus\Nanos1" "Hsap\NANOS2, Hsap\NANOS1, Hsap\NANOS3" " embryonic stage | 0-8 hr , adult stage | female , embryonic stage | stage 3-9 , embryonic stage | early , embryonic stage | stage 2 , embryonic stage | stage 1-2 , oogenesis stage , embryonic stage " " stage S4 oocyte && stage S5 oocyte && stage S6 oocyte

, stage S11 oocyte | posterior && stage S12 oocyte | posterior && stage S13 oocyte | posterior && stage S14 oocyte | posterior , stage S8 oocyte | anterior && stage S9 oocyte | anterior , pole cell

, pole plasm

, pole plasm

{ 0 pumMsc } , organism | 0-10% egg length

, organism | posterior

, pole plasm

{ 0 pumFC8 } ,

posterior ,

0-2% egg length{ - osk*, nosbcd.3UTR } ,

anterior " " embryonic stage | early , adult stage && oogenesis stage " "organism | posterior & gradient

, germline cyst &&of germarium region 2

, posterior | gradient

{ 0 pumFC8 } ,

gradient{ $ osk* } , cystoblast

,

gradient , female germline stem cell

, posterior | gradient

{ 0 pumMsc } " "neuroanatomy defective,viable,fertile,lethal,recessive,female sterile,increased cell death,maternal effect,meiotic cell cycle defective,dominant,partially lethal - majority die,some die during embryonic stage,wild-type,lethal - all die before end of embryonic stage,partially lethal - majority live,visible,somatic clone,partially,female fertile,lethal - all die before end of pupal stage,some die during pupal stage" "mushroom body & axon7B,Kenyon cell,mushroom body & axoney-OK107,abdominal segment,pole cell,maternal effect,germline cell,dorsal closure embryo,embryonic abdominal segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,abdomen,extended germ band embryo,embryonic/first instar larval cuticle,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,filzkorper,embryonic head,embryonic thorax,anterior,embryo,ectopic,posterior,ovariole,egg chamber,germline cyst,class IV dendritic arborizing neuron,female germline stem cell,somatic clone,telson,germarium,female germline stem cell & plasma membrane,cystoblast & plasma membrane,cystocyte & plasma membrane,mitochondrion,testis,ovary,germline stem cell,embryonic epidermis,cephalopharyngeal skeleton,eye,dorsal bridge,vertical bridge,gonad,cystocyte,spectrosome,fusome,egg,dendritic arborising neuron & dendrite | somatic clone,dendritic arborising neuron & dendritic tree8-123,adult cuticle,wing,ommatidium,dendritic arborising neuron & dendritic tree109(2)80,dendritic arborising neuron & dendritic tree477,embryonic thoracic segment" FBgn0035776 CG8564 - http://flybase.org/reports/FBgn0035776 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834 neurogenesis ; GO:0022008 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG8564 "IPR000834:Peptidase M14, carboxypeptidase A, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain" CG8564 11-Aug-17 DroID_v2017_08 "Drer\cpb1, Drer\cpa2, Drer\cpa6, Drer\cpa1, Drer\cpo, Drer\cpa5, Drer\cpa4, Drer\cpb2" Scer\ECM14 "Cele\ZC434.9, Cele\W01A8.6, Cele\T06A4.1, Cele\T06A4.3, Cele\Y47G6A.19, Cele\Y59C2A.1, Cele\suro-1, Cele\Y18H1A.9" "Xtro\cpo, Xtro\cpa1, Xtro\cpa3, Xtro\cpb1, Xtro\cpb2" "Mmus\Cpa6, Mmus\Cpa1, Mmus\Cpa5, Mmus\Cpb2, Mmus\Cpa2, Mmus\Cpa4, Mmus\Cpa3, Mmus\Cpb1" "Hsap\CPA5, Hsap\CPA1, Hsap\CPA2, Hsap\CPA4, Hsap\CPA3, Hsap\CPO, Hsap\CPB2, Hsap\CPB1, Hsap\CPA6" "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0263106 DnaJ-1 DnaJ-like-1 http://flybase.org/reports/FBgn0263106 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR008971 protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P08622 response to heat ; GO:0009408 | inferred from expression pattern microtubule associated complex ; GO:0005875 | inferred from direct assay "dHdj1, DnaJ-1, CG10578, Hsp40, dhdJ1, dnaJ-1, DNAJ-1, DnaJ1, hsp40, DNAJ1, dHDJ1/HSP40, dHDJ1, droj1, Hsp-40, dhdj-1, HSP40, HSP40/HDJ1, DROJ1, DnaJ1 64EF, EU3500, DroJ1, anon-WO0172774.135, anon-WO0140519.166, Hdj1, dhdj1, DmHsp40" "IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site" CG10578 11-Aug-17 DroID_v2017_08 "Drer\dnajb2, Drer\dnajc22, Drer\dnajb14, Drer\dnajc18, Drer\dnajb13, Drer\dnajb4, Drer\dnajb1a, Drer\dnajb1b, Drer\dnajb12a, Drer\dnajb9a, Drer\zgc:122979, Drer\dnajb5, Drer\dnajb12b" "Scer\APJ1, Scer\HLJ1, Scer\ERJ5, Scer\SIS1, Scer\JJJ1, Scer\SCJ1" "Cele\dnj-19, Cele\dnj-1, Cele\dnj-12, Cele\dnj-22, Cele\F54F2.9, Cele\dnj-13" "Xtro\dnajb2, Xtro\dnajc22, Xtro\dnajb6, Xtro\dnajb5, Xtro\dnajb4, Xtro\dnajb12, Xtro\dnajb1, Xtro\dnajb13, Xtro\dnajb9, Xtro\dnajc18, Xtro\dnajb14" "Mmus\Dnajb8, Mmus\Dnajb6, Mmus\Dnajb13, Mmus\Dnajb14, Mmus\Dnajb7, Mmus\Dnajb3, Mmus\Dnajb4, Mmus\Dnajc18, Mmus\Dnajc22, Mmus\Dnajb2, Mmus\Dnajb1, Mmus\Dnajb5, Mmus\Dnajc21, Mmus\Dnajb12, Mmus\Dnajb9" "Hsap\DNAJB14, Hsap\DNAJC22, Hsap\DNAJC18, Hsap\DNAJB7, Hsap\DNAJB4, Hsap\DNAJB8, Hsap\DNAJB9, Hsap\DNAJB5, Hsap\DNAJB1, Hsap\DNAJB13, Hsap\DNAJB2, Hsap\DNAJB6, Hsap\DNAJB12" FBgn0031403 CG15387 - http://flybase.org/reports/FBgn0031403 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15387 IPR026317:Protein C10 CG15387 11-Aug-17 DroID_v2017_08 Drer\grcc10 - Cele\T22B2.3 Xtro\c12orf57 Mmus\Grcc10 Hsap\C12orf57 "viable,visible" mesothoracic tergum FBgn0022279 l(2)IR4 lethal (2) IR4 http://flybase.org/reports/FBgn0022279 - gene - - - l(2)IR4 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0014209 l(1)TW9 lethal (1) TW9 http://flybase.org/reports/FBgn0014209 FBgn0005119 gene - - - "l(1)FMc, l(1)TW9" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0085533 CG40908 - http://flybase.org/reports/FBgn0085533 protein_coding_gene - - - CG40908 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0043903 dome domeless http://flybase.org/reports/FBgn0043903 protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity with HGNC:2170 inferred from sequence or structural similarity with HGNC:6597 inferred from sequence or structural similarity with MGI:MGI:96788 inferred from sequence or structural similarity with MGI:MGI:99605 inferred from genetic interaction with upd1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W266 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with et actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN001491415 transmembrane signaling receptor activity ; GO:0004888 | traceable author statement "border follicle cell migration ; GO:0007298 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype epithelial cell fate determination, open tracheal system ; GO:0007425 | traceable author statement locomotor rhythm ; GO:0045475 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype JAK-STAT cascade ; GO:0007259 | inferred from genetic interaction with hop inferred from genetic interaction with upd1 long-term memory ; GO:0007616 | inferred from mutant phenotype JAK-STAT cascade ; GO:0007259 | inferred from genetic interaction with upd1 inferred from genetic interaction with Stat92E negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype JAK-STAT cascade ; GO:0007259 | traceable author statement regulation of cytoskeleton organization ; GO:0051493 | inferred from biological aspect of ancestor with PANTHER:PTN001491415 hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype regulation of cell migration ; GO:0030334 | inferred from biological aspect of ancestor with PANTHER:PTN001491415 positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype" apicolateral plasma membrane ; GO:0016327 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:2170 inferred from sequence or structural similarity with HGNC:6597 Z disc ; GO:0030018 | inferred from biological aspect of ancestor with PANTHER:PTN001491415 apical plasma membrane ; GO:0016324 | traceable author statement "Dome, dome, 142932_at, DOME, vsp, l(1)G0468, l(1)G0217, CG14226, mom, CT33841, l(1)G0441, l(1)G0405, l(1)G0367, l(1)G0321, l(1)G0264, l(1)G0218, l(1)G0282, anon-18DEb, Domeless, Dom" "IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold" CG14226 11-Aug-17 DroID_v2017_08 "Drer\nexn, Drer\palld" - Cele\unc-40 Xtro\ptprq "Mmus\Mypn, Mmus\Nexn" "Hsap\OSMR, Hsap\NEXN, Hsap\MYPN" "memory defective,RU486 conditional,visible,small body,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,recessive,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,developmental rate defective,wild-type,germline clone,locomotor rhythm defective,immune response defective,conditional,female sterile,viable" "wing vein,ectopic,wing,embryonic/larval spiracle,embryonic/larval posterior spiracle,filzkorper,stigmatophore,border follicle cell,somatic clone,embryonic abdominal segment 5,non-rescuable maternal effect,embryonic abdominal segment 4,posterior,embryonic thoracic segment,rescuable maternal effect,embryonic head,presumptive embryonic/larval tracheal system,embryonic/larval proventriculus,plasmatocyte,germline clone,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,abdominal 4 ventral denticle belt,egg chamber,posterior spiracle primordium,tracheal branch primordium,mouth hooks,egg chamber & basement membrane | apicalslbo.2.6,polar follicle cell,embryonic segment,embryonic hindgut,eye,eye disc anterior to the morphogenetic furrow,eye disc,midgut,embryonic abdominal segment,mesothoracic tergum,epithelium,interfollicle cell" DRSC19583 IE -0.495295078 2.477767577 -0.676930897 1.775472117 -0.035957473 0.365218287 FBgn0003169 put punt http://flybase.org/reports/FBgn0003169 "FBgn0000467, FBgn0004912, FBgn0004920, FBgn0010942, FBgn0011375" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000333, InterPro:IPR000719 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from electronic annotation with InterPro:IPR000333 transforming growth factor beta receptor activity, type II ; GO:0005026 | non-traceable author statement activin-activated receptor activity ; GO:0017002 | inferred from direct assay protein kinase activity ; GO:0004672 | non-traceable author statement activin binding ; GO:0048185 | inferred from direct assay transforming growth factor beta-activated receptor activity ; GO:0005024 | inferred from genetic interaction with dpp transforming growth factor beta receptor activity, type II ; GO:0005026 | inferred from sequence or structural similarity" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271 compound eye morphogenesis ; GO:0001745 | non-traceable author statement dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement dorsal closure ; GO:0007391 | traceable author statement dendrite morphogenesis ; GO:0048813 | non-traceable author statement negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from direct assay open tracheal system development ; GO:0007424 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | traceable author statement primary branching, open tracheal system ; GO:0007428 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from mutant phenotype inferred from genetic interaction with dpp Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype activin receptor signaling pathway ; GO:0032924 | inferred from direct assay" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from sequence model activin receptor complex ; GO:0048179 | inferred from physical interaction with babo "atrII, CG7904, Punt, TGF-B, Atr-II, l(3)10460, STK-C, pun, TGF-beta, l(3)j5A5, dlhC, Tgf-r, AtrII, Atr, Atr88CD, Act-r, put, Put, punt, PUNT" "IPR000333:Ser/Thr protein kinase, TGFB receptor, IPR000472:Activin types I and II receptor domain, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG7904 11-Aug-17 DroID_v2017_08 "Drer\tgfbr2, Drer\bmpr2a, Drer\acvr2ab, Drer\LOC100331938, Drer\acvr2b, Drer\acvr2aa, Drer\bmpr2b, Drer\si:dkey-101k6.5" - "Cele\daf-1, Cele\daf-4" "Xtro\tgfbr2, Xtro\acvr2b, Xtro\acvr2a, Xtro\bmpr2" "Mmus\Amhr2, Mmus\Acvr2a, Mmus\Bmpr2, Mmus\Tgfbr2, Mmus\Acvr2b" "Hsap\ACVR2B, Hsap\AMHR2, Hsap\ACVR2A, Hsap\BMPR2, Hsap\TGFBR2" " embryonic stage | stage 11-16 , embryonic stage | stage 6-11 , adult stage && oogenesis stage , larval stage | third instar , embryonic stage | stage 1-4 , embryonic stage | stage 5 , embryonic stage -- adult stage " " embryonic/larval foregut

, mesoderm

, oocyte

, imaginal disc

,

ubiquitous , pole cell

, embryonic/larval hindgut

, nurse cell

, embryonic/larval midgut

" " embryonic stage | stage 11-16 , embryonic stage | stage 14-16 , embryonic stage | stage 6-11 , embryonic stage | stage 11-13 , embryonic stage | stage 4 , embryonic stage | stage 5 " " embryonic/larval hindgut

, anterior embryonic/larval midgut

, mesoderm

, embryonic/larval midgut

, embryonic/larval foregut

,

ubiquitous , pole cell

" "visible,lethal,recessive,maternal effect,partially,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,heat sensitive,neuroanatomy defective,partially lethal - majority die,cold sensitive,viable,small body,wild-type,somatic clone" "female germline stem cell,male germline stem cell,heat sensitive,testis,spermatogonium,sensory mother cell & dorsal mesothoracic disc,crystal cell,plasmatocyte,leg,dorsal,ventral,eye,antenna,wing vein,ectopic,embryonic/first instar larval cuticle,embryonic head,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,wing,dorsocentral bristle,macrochaeta,embryonic dorsal epidermis,germline clone,pigment granule,morphogenetic furrow,eye disc,posterior,somatic clone,photoreceptor cell,dorsal branch primordium,primary pigment cell,tertiary pigment cell,intersegmental nerve,abdominal segmental nerve,somatic muscle,embryonic epidermis,wing margin,dorsal mesothorax,distal,sex comb,ommatidium,interommatidial bristle,dorsal closure embryo,dorsal cluster neuron & axon | somatic clone,dorsal cluster neuron & neurite | somatic clone,protocerebrum,optic lobe,fascicle,dorsal cluster neuron,heart primordium,presumptive embryonic/larval peripheral nervous system,ventral nerve cord,salivary gland,Malpighian tubule,embryonic/larval dorsal branch,embryonic/larval lateral trunk,germline cell,embryo,anterior,embryonic/larval tracheal system,dorsal cluster neuron & neurite | somatic clone | conditional ts,wing vein L2,wing vein L3,wing vein L4,wing vein L5,anterior crossvein,wing cell,posterior compartment,scutum & macrochaetatsh-Gal4-1,scutum & macrochaetahs.PB,mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell,bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0024273 WASp WASp http://flybase.org/reports/FBgn0024273 FBgn0039603 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR003124 actin binding ; GO:0003779 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Abi positive regulation of Arp2/3 complex-mediated actin nucleation ; GO:2000601 | inferred from electronic annotation with InterPro:IPR027641 clathrin-dependent endocytosis ; GO:0072583 | inferred from mutant phenotype apical constriction ; GO:0003383 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from direct assay axonal fasciculation ; GO:0007413 | inferred from genetic interaction with SCAR myoblast fusion ; GO:0007520 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from genetic interaction with SCAR cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype epidermal cell differentiation ; GO:0009913 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from genetic interaction with Arp3 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | traceable author statement regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from direct assay sensory organ development ; GO:0007423 | inferred from mutant phenotype membrane budding ; GO:0006900 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | traceable author statement spermatid development ; GO:0007286 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype microtubule bundle formation ; GO:0001578 | inferred from direct assay myoblast fusion ; GO:0007520 | inferred from genetic interaction with Whamy cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay microvillus ; GO:0005902 | inferred from mutant phenotype rhabdomere ; GO:0016028 | inferred from mutant phenotype protein complex ; GO:0043234 | colocalizes_with inferred from physical interaction with Abi neuromuscular junction ; GO:0031594 | inferred from direct assay "Wasp, Wsp, wasp, wsp, WASP, Dm WASP, dWASP, CG1520, D-WASP, WASp, DmWASP, WSP" "IPR000095:CRIB domain, IPR000697:WH1/EVH1 domain, IPR003124:WH2 domain, IPR011026:Wiscott-Aldrich syndrome protein, C-terminal, IPR011993:PH domain-like, IPR033927:WASP family, EVH1 domain, IPR027641:Wiskott-Aldrich syndrome protein" CG1520 11-Aug-17 DroID_v2017_08 "Drer\wasla, Drer\wasa, Drer\wasb, Drer\si:dkey-197j19.6, Drer\waslb" Scer\LAS17 "Cele\B0280.2, Cele\B0280.13, Cele\wsp-1, Cele\C31C9.6" "Xtro\wasl, Xtro\was" "Mmus\Wasl, Mmus\Was" "Hsap\ASB15, Hsap\WASL, Hsap\WAS" "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,cell shape defective,lethal,neuroanatomy defective,male sterile,hypoactive,recessive,behavior defective,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,visible,rescuable maternal effect,partially lethal - majority die,some die during pupal stage,conditional,lethal - all die during embryonic stage" "embryonic myoblast,muscle attachment site,myoblast,plasma membrane | embryonic stage,dorsal acute muscle,embryonic/larval somatic muscle,ectoderm | extended germ band stage,head bristle,adult abdominal sensillum,leg & microchaeta3450),adult thorax & microchaeta3450),macrochaeta,interommatidial bristle,supernumerary,tormogen cell,trichogen cell,interommatidial bristle & eo neuron | supernumerary3450),interommatidial bristle & tormogen cell3450),interommatidial bristle & trichogen cell3450),sensory mother cell,embryonic/larval neuromuscular junction,synaptic vesicle | third instar larval stage3450),NMJ bouton,rhabdomere | adult stage | somatic clone3450),somatic clone,spermatid cyst,seminal vesicle,head cyst cell,actin filament3450)arm.PS, WASpH242D.UAS,macrochaeta & adult head | somatic clone,microchaeta & adult head | somatic clone,neuromuscular junction | larval stage,bouton,rhabdomere,embryonic peripheral nervous system & neuron | supernumerary | germ-line clone3450),embryonic peripheral nervous system & external sensory organ | germ-line clone3450),RP2 motor neuron,adult thorax & microchaeta & external sensory organ precursor cell IIa3450),adult thorax & microchaeta & external sensory organ precursor cell IIb3450),microchaeta,dorsocentral bristle,scutellar bristle,notopleural bristle,microvillus & eye photoreceptor cell | somatic clone,actin filament & eye photoreceptor cell | somatic clone,eye disc,ventral nerve cord,rescuable maternal effect,denticle,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,external sensory organ,mesothoracic bristle & eo neuron | supernumerary,mesothoracic bristle & tormogen cell,mesothoracic bristle & trichogen cell,chaeta,actin filament, with Df(3R)3450/WASp1, arm.PS,adult brain,mitochondrionelav.PU,neuromuscular junctionC57,dorsal multidendritic neuron ddaC | pupal stage,dorsal multidendritic neuron ddaC,conditional" FBgn0020493 Dad Daughters against dpp http://flybase.org/reports/FBgn0020493 "FBgn0024521, FBgn0025250, FBgn0062662" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR013019 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ; GO:0030617 | traceable author statement transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ; GO:0030617 | inferred from genetic interaction with tkv inferred from genetic interaction with Mad protein binding ; GO:0005515 | inferred from physical interaction with sax inferred from physical interaction with tkv" "cell elongation involved in imaginal disc-derived wing morphogenesis ; GO:0090254 | inferred from mutant phenotype BMP signaling pathway involved in Malpighian tubule cell chemotaxis ; GO:0061353 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of phosphorylation ; GO:0042325 | inferred from direct assay histoblast morphogenesis ; GO:0007488 | inferred from mutant phenotype negative regulation of muscle organ development ; GO:0048635 | inferred from mutant phenotype negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | traceable author statement morphogenesis of larval imaginal disc epithelium ; GO:0016335 | inferred from mutant phenotype retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from genetic interaction with Acsl negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from mutant phenotype inferred from genetic interaction with tkv inferred from genetic interaction with Mad anterior/posterior pattern specification, imaginal disc ; GO:0007448 | inferred from mutant phenotype" transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR013019 "Dad, dad, l(3)j1E4, DAD, 1883, EP(3)3196, anon-EST:fe1F5, EP3196, CG5201" "IPR001132:SMAD domain, Dwarfin-type, IPR003619:MAD homology 1, Dwarfin-type, IPR008984:SMAD/FHA domain, IPR013019:MAD homology, MH1, IPR013790:Dwarfin, IPR017855:SMAD domain-like" CG5201 11-Aug-17 DroID_v2017_08 "Drer\smad9, Drer\smad2, Drer\smad7, Drer\si:dkey-222b8.1, Drer\si:dkey-239n17.4, Drer\smad5, Drer\smad6b, Drer\gb:cr929477, Drer\smad4a, Drer\smad6a, Drer\smad3a, Drer\smad3b" - "Cele\tag-68, Cele\sma-3, Cele\daf-14" "Xtro\smad6.2, Xtro\smad1, Xtro\smad4.2, Xtro\smad9, Xtro\smad3, Xtro\smad6, Xtro\smad7, Xtro\smad2, Xtro\smad4.1" "Mmus\Smad6, Mmus\Smad7, Mmus\Smad5, Mmus\Smad4, Mmus\Smad1, Mmus\Smad3, Mmus\Smad9, Mmus\Smad2" "Hsap\SMAD4, Hsap\SMAD6, Hsap\SMAD7, Hsap\SMAD2, Hsap\SMAD9, Hsap\SMAD3, Hsap\SMAD1, Hsap\SMAD5" larval stage | third instar dorsal mesothoracic disc | restricted

"partially lethal - majority die,visible,lethal,recessive,endocytosis defective,dominant,neuroanatomy defective,cell lethalcell lethal,somatic clone,mitotic cell cycle defective,cell autonomous,cell non-autonomous,cell shape defective,increased cell death,neurophysiology defective" "wing vein L2,wing vein,dorsal appendage,ectopic,wing,NMJ bouton,supernumerary,female germline stem cell,bouton,neuromuscular junction,wing disc,cell autonomous,cell non-autonomous,medial,spermatocyte,spermatogonium,male germline stem cell,testis,germline cell,female | larval stage,germline cyst,wing margin,eye disc & peripodial epitheliumc311,peripodial epithelium,ventral thoracic disc,wing pouch,eye photoreceptor cell stalk,lamina tangential neuron,lamina intrinsic neuron,lamina,lamina anlage glial cell,dorsal branch primordium,tracheal tip cell | embryonic stage,neuromuscular junctionRapGAP1-OK6,somatic clone,fat body,maxillary palpus,vibrissae,amnioserosa,embryonic dorsal epidermis,filamentous actinpAS,egg operculum,mesothoracic extracoxal depressor muscle 66,thoracic adult muscle precursor cell,embryonic anterior Malpighian tubule,histoblast,histoblast nest,wing vein L4,wing vein L5,anterior crossvein,adult brain" FBgn0004567 slp2 sloppy paired 2 http://flybase.org/reports/FBgn0004567 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "slp, Slp, Dmslp2, FD7, CG2939, slp2, FoxG, SLP, Slp2" "IPR018122:Fork head domain conserved site1, IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG2939 11-Aug-17 DroID_v2017_08 "Drer\foxq2, Drer\foxg1c, Drer\foxg1b, Drer\foxg1a, Drer\foxl1, Drer\si:ch211-262e15.1, Drer\foxb1b, Drer\foxd3, Drer\foxb1a, Drer\foxb2, Drer\foxd2, Drer\foxk2, Drer\foxk1, Drer\foxg1d, Drer\foxj1a" "Scer\FKH1, Scer\FHL1, Scer\FKH2, Scer\HCM1" "Cele\fkh-10, Cele\fkh-2, Cele\pes-1, Cele\lin-31, Cele\fkh-9, Cele\unc-130" "Xtro\foxe1, Xtro\foxd4l1.1, Xtro\foxb1, Xtro\foxj1, Xtro\foxk2, Xtro\foxd3, Xtro\foxj1.2, Xtro\foxi4.2, Xtro\foxd2, Xtro\foxe3" "Mmus\Foxg1, Mmus\Foxb2, Mmus\Foxj1, Mmus\Foxb1, Mmus\Foxk2, Mmus\Foxk1, Mmus\Foxl1, Mmus\Foxd3" "Hsap\FOXL1, Hsap\FOXG1, Hsap\FOXK1, Hsap\FOXD3, Hsap\FOXB2, Hsap\FOXD4, Hsap\FOXK2, Hsap\FOXB1, Hsap\FOXJ1" " embryonic stage | stage >7 , embryonic stage , embryonic stage | stage 6 , embryonic stage | stage 4 | late , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | stage >=13 " " labral segment

, mandibular segment

, intercalary segment

, organism | gap

,

segment polarity , embryonic procephalic segment | lateral

,

71-85% egg length & ventral , organism | pair rule

, organism | 70-80% egg length & dorsal

, organism | even pair rule

, ventral nerve cord

, proventriculus

" " embryonic stage | stage 7 , embryonic stage | stage 8 " " organism | pair rule

,

segment polarity " "lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "embryonic/larval dorsal vessel,abdominal 8 ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,RP2 motor neuron,ectopic,RP2sib neuron,neuroblast NB4-2,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,cuticle,denticle belt" FBgn0038487 TwdlW TweedleW http://flybase.org/reports/FBgn0038487 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "CG4060, TwdlW" "IPR004145:Domain of unknown function DUF243, IPR015943:WD40/YVTN repeat-like-containing domain" CG4060 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0024179 wit wishful thinking http://flybase.org/reports/FBgn0024179 "FBgn0014282, FBgn0015807, FBgn0027362, FBgn0027993, FBgn0035493" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000333, InterPro:IPR000719, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from electronic annotation with InterPro:IPR000333 transmembrane receptor protein serine/threonine kinase activity ; GO:0004675 | inferred from electronic annotation with InterPro:IPR000472 protein kinase activity ; GO:0004672 | non-traceable author statement transforming growth factor beta receptor activity, type II ; GO:0005026 | inferred from sequence or structural similarity" transmembrane receptor protein serine/threonine kinase signaling pathway ; GO:0007178 | inferred from electronic annotation with InterPro:IPR000333 protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from sequence or structural similarity dendrite morphogenesis ; GO:0048813 | non-traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000333, InterPro:IPR000472 early endosome ; GO:0005769 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity synapse ; GO:0045202 | inferred from direct assay trans-synaptic protein complex ; GO:0098820 | inferred from genetic interaction with Nrx-1, Nlg1 recycling endosome ; GO:0055037 | inferred from direct assay" "CG10776, STK-D, ALK3/BMPRII, l(3)64Aa, 1262/15, SE20, l(3)SH12, l(3)S126215, Stk-D, wit, Wit, WIT, Wit-C, BMP" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR000333:Ser/Thr protein kinase, TGFB receptor, IPR000472:Activin types I and II receptor domain" CG10776 11-Aug-17 DroID_v2017_08 "Drer\tgfbr2, Drer\bmpr2b, Drer\acvr2ab, Drer\si:dkey-101k6.5, Drer\acvr2aa, Drer\bmpr2a, Drer\acvr2b, Drer\LOC100331938" Scer\YPK3 Cele\daf-4 "Xtro\tgfbr2, Xtro\acvr2a, Xtro\acvr2b, Xtro\bmpr2" "Mmus\Bmpr2, Mmus\Acvr2b, Mmus\Amhr2, Mmus\Tgfbr2, Mmus\Acvr2a" "Hsap\ACVR2A, Hsap\ACVR2B, Hsap\AMHR2, Hsap\TGFBR2, Hsap\BMPR2" " embryonic stage | stage 11-14 , embryonic stage | stage >=15 , embryonic stage | stage 16-17 , embryonic stage | stage 14 " " ventral nerve cord primordium | restricted

, embryonic central nervous system

, embryonic/larval midgut | restricted

, amnioserosa

, embryonic central nervous system | restricted

" " larval stage , embryonic stage | stage 13 , larval stage | first instar -- L | second instar , larval stage | third instar , embryonic stage | stage 13-17 , embryonic stage | stage 13-14 , embryonic stage | stage 16-17 " " larval brain

, VUM neuron

, ventral nerve cord

, imaginal disc

, lateral cord neuron

, ventral nerve cord primordium | restricted

, RP2 neuron

, motor neuron

" "neuroanatomy defective,viable,fertile,lethal,recessive,neurophysiology defective,wild-type,lethal - all die before end of P-stage,some die during pharate adult stage,size defective,maternal effect,visible,circadian rhythm defective" "bouton,neuromuscular junction,embryonic/larval muscle system,synapse,NMJ bouton,A2 neuron,A3 neuron,embryonic/larval neuromuscular junction,type I bouton,supernumerary,leg,tarsal segment,metathoracic femur,metathoracic tibia,femur,tibia,postsynaptic membrane,synapse | larval stage,wing vein L5,posterior crossvein,synapseRapGAP1-OK6,chaeta" FBgn0026379 Pten Phosphatase and tensin homolog http://flybase.org/reports/FBgn0026379 FBgn0032201 protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR017361 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity ; GO:0016314 | inferred from sequence or structural similarity with HGNC:9588 inferred from genetic interaction with Pi3K92E inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity ; GO:0051717 | inferred from sequence or structural similarity with UniProtKB:P60484 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement phosphoprotein phosphatase activity ; GO:0004721 | inferred from mutant phenotype protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with UniProtKB:P60484 protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with UniProtKB:P60484 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from sequence or structural similarity PDZ domain binding ; GO:0030165 | inferred from sequence or structural similarity with UniProtKB:P60484 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity ; GO:0051800 | inferred from sequence or structural similarity with UniProtKB:P60484 phosphatidylinositol-3-phosphatase activity ; GO:0004438 | inferred from sequence or structural similarity with UniProtKB:P60484 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from mutant phenotype non-membrane spanning protein tyrosine phosphatase activity ; GO:0004726 | inferred from sequence or structural similarity phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with HGNC:9588" "phosphatidylinositol dephosphorylation=0046856 |... electronic annotation with InterPro:IPR017361 <> negative regulation of organ growth=0046621 | <> insulin receptor signaling pathway=0008286 | <> regulation of cell shape=0008360 |...<> negative regulation of growth=0045926 | <> protein kinase B signaling=0043491 |... with UniProtKB:Q8INB9 <> protein dephosphorylation=0006470 |... sequence or structural similarity with HGNC:9588 <> regulation of cell size=0008361 |...<> negative regulation of cell size=0045792 | <> negative regulation of organ growth=0046621 |...<> autophagy=0006914 |...<> regulation of hemocyte proliferation=0035206 |...<> regulation of multicellular organism growth=0040014 |...<> protein dephosphorylation=0006470 |...<> cell proliferation=0008283 |...<> regulation of autophagy=0010506 |...<> lipid metabolic process=0006629 |...<> melanotic encapsulation of foreign target=0035011 |...<> cell adhesion=0007155 |...<> actin filament organization=0007015 |...<> animal organ morphogenesis=0009887 |...<> larval development=0002164 |...<> regulation of organ growth=0046620 | <> basement membrane organization=0071711 |...<> tissue development=0009888 |...<> negative regulation of insulin receptor signaling pathway=0046627 | <> lipid storage=0019915 |...<> actin cytoskeleton organization=0030036 |...<> negative regulation of cell proliferation=0008285 |... sequence or structural similarity with UniProtKB:P60484 <> regulation of cell size=0008361 | <> regulation of dendrite development=0050773 |...<> inositol phosphate dephosphorylation=0046855 |... sequence or structural similarity with UniProtKB:P60484 <> apoptotic process=0006915 | <> cytoskeleton organization=0007010 |...<> dendrite regeneration=0031104 |...<> protein dephosphorylation=0006470 |... sequence or structural similarity with UniProtKB:P60484 <> response to starvation=0042594 |...<> phosphatidylinositol dephosphorylation=0046856 | <> epithelial cell fate determination, open tracheal system=0007425 |...<> regulation of establishment of planar polarity=0090175 |...<> apoptotic process=0006915 |...<> negative regulation of cell cycle=0045786 | <> negative regulation of insulin receptor signaling pathway=0046627 | <> regulation of cell junction assembly=1901888 |...<> larval midgut histolysis=0035069 |... with Atg18a inferred from with Atg1 <> negative regulation of multicellular organism growth=0040015 |...<> protein dephosphorylation=0006470 | <> negative regulation of cell migration=0030336 |... sequence or structural similarity with UniProtKB:P60484 <> metamorphosis=0007552 |...<> negative regulation of cell growth=0030308 | <> cell competition in a multicellular organism=0035212 |...<> neuron remodeling=0016322 |...<> negative regulation of protein kinase B signaling=0051898 |... sequence or structural similarity with UniProtKB:P60484 <> rhabdomere development=0042052 |...<> regulation of multicellular organism growth=0040014 | <> insulin receptor signaling pathway=0008286 |... with Pi3K92E inferred from with chico <> negative regulation of organ growth=0046621 | <> phosphatidylinositol dephosphorylation=0046856 | <> larval salivary gland morphogenesis=0007436 |...<> cellular process=0009987 |...<> ovarian follicle cell development=0030707 |...<> regulation of cell cycle=0051726 |...<> negative regulation of axon regeneration=0048681 |...<> negative regulation of focal adhesion assembly=0051895 |... sequence or structural similarity with UniProtKB:P60484 <> somatic muscle development=0007525 |...<> regulation of protein stability=0031647 |... sequence or structural similarity with UniProtKB:P60484 <> cellular protein localization=0034613 |... mutant phenotype" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:9588 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:9588 "pten, PTEN, dPTEN, DPTEN, PTEN3, CG5671, Pten, dPten, dpten" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR014020:Tensin phosphatase, C2 domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR017361:Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN, IPR000008:C2 domain, IPR029023:Tensin-type phosphatase domain, IPR029021:Protein-tyrosine phosphatase-like" CG5671 11-Aug-17 DroID_v2017_08 "Drer\tns2b, Drer\ptena, Drer\tpte, Drer\cdc14b, Drer\gak, Drer\si:ch211-191a24.3, Drer\tns1b, Drer\tns2a, Drer\ptenb, Drer\dnajc6, Drer\tns1a, Drer\cdc14ab" "Scer\TEP1, Scer\CDC14" Cele\daf-18 "Xtro\tpte2, Xtro\gak, Xtro\tns2, Xtro\pten, Xtro\dnajc6, Xtro\tns1" "Mmus\Tpte, Mmus\Dnajc6, Mmus\Pten, Mmus\Tns3, Mmus\Cdc14b, Mmus\Tns1, Mmus\Tns2, Mmus\Gak" "Hsap\GAK, Hsap\TNS1, Hsap\DNAJC6, Hsap\TNS2, Hsap\TPTE, Hsap\CDC14B, Hsap\TPTE2, Hsap\PTEN, Hsap\TNS3" "visible,size defective,decreased cell size,somatic clone,increased cell size,increased cell number,dominant,neurophysiology defective,neuroanatomy defective,wild-type,lethal,recessive,hyperplasia,lethal - all die before end of larval stage,some die during third instar larval stage,viable,large body,stress response defective,planar polarity defective,cell autonomous,some die during larval stage,neoplasia,decreased cell number,partially lethal - majority die,developmental rate defective,lethal - all die before end of pupal stage,partially,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,long lived,RU486 conditional,small body,aging defective,short lived,chemical resistant,heat sensitive,immune response defective,increased cell growth" "eye,ommatidium,embryonic/larval midgut,somatic clone,egg,germline clone,maternal effect,pole cell,cleavage stage embryo,blastoderm embryo,gastrula embryo,nurse cell & actin cytoskeleton | germ-line clone,nurse cell,nurse cell & nucleus | germ-line clone,eye photoreceptor cell,interommatidial bristle,wing margin bristle,eye disc,wing,NMJ bouton,photoreceptor cell,cell autonomous,rhabdomere | cell autonomous | somatic clone,wing & cell | somatic clone,wing hair,ectopic,crossvein,ommatidial precursor cluster,dorsal multidendritic neuron ddaC,epithelial cell,lipid particle & nurse cell | somatic clone,rhabdomere,dendrite | cell autonomous | somatic clone,wing disc,tracheal primordium,mesothoracic tracheal primordium,metathoracic tracheal primordium,abdominal tracheal primordium 1,abdominal tracheal primordium 2,adult head,glial cell,supernumerary,optic lobe,head capsule,posterior compartment,wing blade,embryo | dorsal closure stage,embryonic leading edge cell,prothoracic gland,embryonic/larval corpus allatum,puparium,embryonic/larval salivary gland,embryonic/larval fat body,dorsal compartment,adult heart,fat body,cell cycleey.PH,pigment cell,lens,rhabdomereGMR.PF,lipid droplet & larval oenocyteppl.PP,dendrite | larval stageppk.PG,muscle cell,embryonic/larval neuroblast,posterior signalling centre of lymph gland primary lobe | third instar larval stage,plasmatocyte | third instar larval stage,crystal cell | third instar larval stage,segment border muscle,A1-7 dorsal acute muscle 1,embryonic/first instar larval cuticle | first instar larval stage,chaeta,mesothoracic tergum,heat sensitive,cell junction | pupal stage | heat sensitiveen.PU, GAL80ts.‘±Tub84B,adult cuticle,somatic clone | third instar larval stage" DRSC03402 I 0.079375872 -2.655570592 0.197480659 0.198512374 0.05677846 -0.27793771 FBgn0033438 Mmp2 Matrix metalloproteinase 2 http://flybase.org/reports/FBgn0033438 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001818, InterPro:IPR006026, InterPro:IPR021190 metalloendopeptidase activity ; GO:0004222 | inferred from direct assay endopeptidase activity ; GO:0004175 | inferred from direct assay" "cell-cell junction organization ; GO:0045216 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype negative regulation of fibroblast growth factor receptor signaling pathway ; GO:0040037 | inferred from direct assay protein processing ; GO:0016485 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype ovulation ; GO:0030728 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype tracheal pit formation in open tracheal system ; GO:0035202 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype basement membrane disassembly ; GO:0034769 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with wg tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype adult fat body development ; GO:0007505 | inferred from mutant phenotype fasciculation of motor neuron axon ; GO:0097156 | inferred from mutant phenotype negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from genetic interaction with arm activation of innate immune response ; GO:0002218 | inferred from direct assay open tracheal system development ; GO:0007424 | inferred from mutant phenotype basement membrane organization ; GO:0071711 | inferred from mutant phenotype" "extracellular matrix ; GO:0031012 | inferred from electronic annotation with InterPro:IPR001818, InterPro:IPR021190 external side of plasma membrane ; GO:0009897 | inferred from direct assay dendrite ; GO:0030425 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay" "MMP2, dm-2MMP, l(2)02353, 2-MMP, Dm2-MMP, CG1794, anon-WO0118547.84, Mmp2, mmp2, dmmp2, Matrix metalloproteinase 2" "IPR018487:Hemopexin-like repeats, IPR000585:Hemopexin-like domain, IPR001818:Peptidase M10, metallopeptidase, IPR002477:Peptidoglycan binding-like, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR021190:Peptidase M10A, IPR033739:Peptidase M10A, catalytic domain" CG1794 11-Aug-17 DroID_v2017_08 "Drer\mmp16b, Drer\mmp19, Drer\prg4a, Drer\vtna, Drer\mmp23bb, Drer\zgc:152945, Drer\mmp11a, Drer\mmp28, Drer\mmp30, Drer\mmp15a, Drer\mmp24, Drer\hpx, Drer\mmp25b, Drer\mmp17b, Drer\mmp15b, Drer\mmp20b, Drer\mmp14b, Drer\mmp20a, Drer\mmp13a, Drer\mmp9, Drer\mmp11b, Drer\mmp13b, Drer\mmp14a, Drer\mmp16a, Drer\mmp23ba, Drer\mmp17a, Drer\mmp21, Drer\mmp25a, Drer\mmp2" - "Cele\zmp-1, Cele\W01F3.2, Cele\zmp-6, Cele\zmp-5, Cele\K03B8.6, Cele\zmp-2, Cele\zmp-3" "Xtro\mmp24, Xtro\mmp14, Xtro\mmp1, Xtro\mmp28, Xtro\mmp13, Xtro\prg4, Xtro\alg8, Xtro\mmp9, Xtro\mmp11, Xtro\mmp16, Xtro\mmp21, Xtro\mmp3, Xtro\mmp17, Xtro\mmp8, Xtro\LOC100490019, Xtro\hpx, Xtro\mmp2, Xtro\vtn, Xtro\mmp15, Xtro\mmp25, Xtro\mmp19" "Mmus\Bsph1, Mmus\Mmp23, Mmus\Mmp16, Mmus\Mmp15, Mmus\Mmp9, Mmus\Mmp20, Mmus\Mmp3, Mmus\Mmp25, Mmus\Mmp27, Mmus\Alg8, Mmus\Mmp2, Mmus\Mmp12, Mmus\Mmp24, Mmus\Vtn, Mmus\Hpx, Mmus\Mmp11, Mmus\Mmp28, Mmus\Mmp1b, Mmus\Mmp13, Mmus\Mmp10, Mmus\Mmp7, Mmus\Mmp8, Mmus\Mmp1a, Mmus\Mmp17, Mmus\Prg4, Mmus\Mmp19, Mmus\Mmp21, Mmus\Bsph2, Mmus\Mmp14" "Hsap\MMP11, Hsap\MMP19, Hsap\MMP23B, Hsap\MMP13, Hsap\MMP25, Hsap\MMP7, Hsap\ALG8, Hsap\MMP1, Hsap\VTN, Hsap\MMP21, Hsap\MMP24, Hsap\MMP14, Hsap\HPX, Hsap\BSPH1, Hsap\ELSPBP1, Hsap\MMP26, Hsap\MMP2, Hsap\MMP16, Hsap\MMP27, Hsap\MMP3, Hsap\MMP17, Hsap\MMP9, Hsap\MMP20, Hsap\MMP15, Hsap\MMP8, Hsap\PRG4, Hsap\MMP10, Hsap\MMP12, Hsap\MMP28" " larval stage | third instar , adult stage | male , embryonic stage&&larval stage&&pupal stage , adult stage | female " " eye disc

, lamina

, larval optic lobe

, morphogenetic furrow | posterior to

, dorsal mesothoracic disc

" "lethal,recessive,melanotic mass phenotype,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,sterile,hyperplasia" "tracheal air sac,heat sensitive,dorsal air sac primordium tip cell,wing,leg,basement membrane | pupal stage,mesothoracic tergum,gastric caecum,embryonic/larval proventriculus,dendritic arborizing neuron,embryonic/larval transverse connective,dorsal air sac primordium,wing disc,intersegmental nerve branch ISNb of A1-7,head,interommatidial bristle,ommatidium,intersegmental nerve branch ISNb of A1-7 | embryonic stage,segmental nerve branch SNa of A1-7 | embryonic stage,adult thorax,embryonic/larval transverse connective | third instar larval stage,dorsal air sac primordium | third instar larval stage,wing disc | third instar larval stage" DRSC22024 K 0.076338193 0.742320534 -0.090025995 0.069754853 -2.809413098 -0.329799802 FBgn0001233 Hsp83 Heat shock protein 83 http://flybase.org/reports/FBgn0001233 "FBgn0004639, FBgn0010233, FBgn0011792, FBgn0016742, FBgn0024852, FBgn0044664" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001404, InterPro:IPR019805 unfolded protein binding ; GO:0051082 | inferred from direct assay" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001404, InterPro:IPR019805 spermatogenesis ; GO:0007283 | inferred from mutant phenotype centrosome cycle ; GO:0007098 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from expression pattern oogenesis ; GO:0048477 | inferred from genetic interaction with cup R7 cell fate commitment ; GO:0007465 | traceable author statement pole plasm mRNA localization ; GO:0019094 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | non-traceable author statement negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype protein folding ; GO:0006457 | traceable author statement regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | traceable author statement proteasome assembly ; GO:0043248 | inferred from direct assay actin filament organization ; GO:0007015 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement cold acclimation ; GO:0009631 | inferred from expression pattern regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype" centrosome ; GO:0005813 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "Hsp83, 143198_at, hsp83, Hsp90, hsp90, Hsp82, HSP82, HSP90, CG1242, anon-WO0068693, en(lz)3C/4C, hsp82, ORF1, ms(3)08445, DMHSP82, clone 2.53, E(sina)2, l(3)j5C2, HSP83, E(sev)3A, hsp84, 83, 83K HSP, stc, anon-EST:Liang-2.53, Su(Raf)3A, anon-WO0140519.209, P02828, HSP90A1, DmHsp83" "IPR001404:Heat shock protein Hsp90 family, IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR019805:Heat shock protein Hsp90, conserved site, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR020575:Heat shock protein Hsp90, N-terminal" CG1242 11-Aug-17 DroID_v2017_08 "Drer\hsp90ab1, Drer\hsp90b1, Drer\hsp90aa1.2, Drer\hsp90aa1.1" "Scer\HSC82, Scer\HSP82" "Cele\enpl-1, Cele\daf-21" "Xtro\hsp90b1, Xtro\hsp90aa1.1, Xtro\hsp90aa1.2, Xtro\hsp90ab1" "Mmus\Hsp90aa1, Mmus\Hsp90b1, Mmus\Hsp90ab1" "Hsap\HSP90B1, Hsap\HSP90AA1, Hsap\HSP90AB1" "lethal,recessive,viable,lethal - all die during third instar larval stage,developmental rate defective,fertile,locomotor rhythm defective,male sterile,female fertile,behavior defective,female semi-fertile,cell polarity defective,lethal - all die before end of pupal stage,partially lethal,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,short lived,male,partially lethal - majority die,female,visible,cell cycle defective" "spermatid,Nebenkern,spermatozoon,anterior dorsocentral bristle,posterior dorsocentral bristle,humeral bristle,scutellar bristle,supernumerary,metathoracic bristle,mesothoracic bristle,embryonic abdominal segment,maternal effect,spermatocyte,primary spermatocyte cyst,spermatid axoneme,Nebenkern derivative,primary spermatocyte,neuroblast,mitotic cell cycle,centrosome,egg chamber,nurse cell,egg,dorsal appendage,chaeta,photoreceptor cell R7,secondary pigment cell,wing,eye,dorsal" DRSC08664 IEK 0.742417259 1.779918004 0.744652459 -1.817842774 1.629574 2.337558348 FBgn0000179 bi bifid http://flybase.org/reports/FBgn0000179 "FBgn0002996, FBgn0003183, FBgn0004104" protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR008967, InterPro:IPR018186 protein binding ; GO:0005515 | inferred from physical interaction with zld transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from sequence or structural similarity with UniProtKB:Q13207 DNA binding ; GO:0003677 | inferred from direct assay" "wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with UniProtKB:Q13207 compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype developmental pigmentation ; GO:0048066 | traceable author statement organ growth ; GO:0035265 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from expression pattern imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q13207 nucleus ; GO:0005634 | inferred from direct assay "omb, Omb, Dm-OMB, OMB, dm-omb, Dm-omb, BI, l(1)omb, l(1)bi, Qd, T3, CG3578, bi, TBX2" "IPR018186:Transcription factor, T-box, conserved site, IPR001699:Transcription factor, T-box, IPR008967:p53-like transcription factor, DNA-binding, IPR004088:K Homology domain, type 1, IPR021101:Optomotor-blind protein, N-terminal" CG3578 11-Aug-17 DroID_v2017_08 "Drer\tbx3b, Drer\tbx4, Drer\tbx1, Drer\tbx2a, Drer\tbx6l, Drer\tb, Drer\tbx5b, Drer\tbx22, Drer\tbr1a, Drer\tbx2b, Drer\tbx6, Drer\tbx20, Drer\tbx21, Drer\tbx16, Drer\eomesa, Drer\tbx3a, Drer\tbx5a, Drer\tbx18, Drer\eomesb, Drer\tbr1b, Drer\tbx19, Drer\mgaa, Drer\ta" - "Cele\tbx-7, Cele\mab-9, Cele\tbx-39, Cele\tbx-2, Cele\mls-1" "Xtro\t2, Xtro\tbx1, Xtro\mga, Xtro\tbr1, Xtro\tbx22, Xtro\vegt, Xtro\eomes, Xtro\tbx15, Xtro\tbx4, Xtro\t, Xtro\tbx3, Xtro\tbx18, Xtro\tbx20, Xtro\tbx2, Xtro\tbx5" "Mmus\Tbx1, Mmus\T, Mmus\Tbx18, Mmus\Tbx6, Mmus\Eomes, Mmus\Tbx19, Mmus\Tbx15, Mmus\Tbx20, Mmus\Tbx2, Mmus\Tbx21, Mmus\Tbx5, Mmus\Tbx22, Mmus\Tbx10, Mmus\Mga, Mmus\Tbr1, Mmus\Tbx3, Mmus\Tbx4" "Hsap\TBX4, Hsap\TBX18, Hsap\TBX1, Hsap\TBX19, Hsap\EOMES, Hsap\TBX15, Hsap\TBX10, Hsap\TBR1, Hsap\TBX6, Hsap\TBX20, Hsap\TBX2, Hsap\MGA, Hsap\TBX5, Hsap\TBX3, Hsap\TBX22, Hsap\TBX21, Hsap\T" " embryonic stage | stage 12 , larval stage | third instar , embryonic stage | stage 8 , prepupal stage , embryonic stage | stage 11-16 , adult stage , embryonic stage | stage 11 , embryonic stage | stage 17 , embryonic stage | stage 13-15 , embryonic stage | stage 10 " " procephalic segment

, eye-antennal disc

, inner proliferation zone

, ventral nervous system | segmentally repeated

, larval brain

, medulla cortex

, suture &&of larval outer optic anlage

, antennal segment

, larval optic lobe

, antenno-maxillary complex

, lamina neuropil

, peripheral nervous system precursor cluster

, ventral nerve cord

, protocerebrum

, embryonic peripheral nervous system

, ventral body

" larval stage | third instar dorsal mesothoracic disc | restricted

"visible,dominant,viable,fertile,recessive,eye color defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,partially lethal - majority die,sterile,male,body color defective,neurophysiology defective,cell autonomous,somatic clone,planar polarity defective,cell non-autonomous,lethal - all die before end of P-stage,some die during pharate adult stage,optomotor response defective,behavior defective,semidominant,visual behavior defective,phototaxis defective,heat sensitive,size defective,lethal - all die before end of larval stage,female,some die during larval stage" "wing vein,wing vein L3,distal,wing margin,wing,proximal,eye,pigment cell,tergite,female,posterior,horizontal system neuron,optic chiasma,lobula,anterior,abdominal tergite & macrochaeta,sternite | anterior & trichome,wing vein L4,adult cuticle & abdominal segment | male,somatic clone,adult abdominal segment 3,ectopic,adult abdominal segment,posterior compartment,hypandrial bristle,hypandrial hair,hypandrium,anal plate,epiproct,hypoproct,clasper long bristle,dorsal,abdominal tergite & trichome,abdominal sternite & trichome,adult abdomen,wing disc,anterior/posterior compartment boundary,adult cuticle & abdomen | somatic clone | cell autonomous,microchaeta,abdominal tergite | posterior & trichome,lobula plate,optic lobe,dorsal margin photoreceptor,heat sensitive,wing hinge,wing sensillum,wing pouch,wing vein L5,cell non-autonomous,arista,ommatidium,leg,adult cuticle & abdomen | somatic cloneUbx.PdC,tarsal segment,male,wing blade" FBgn0000591 E(spl)m8-HLH "Enhancer of split m8, helix-loop-helix" http://flybase.org/reports/FBgn0000591 - protein_coding_gene "protein homodimerization activity ; GO:0042803 | inferred from physical interaction with E(spl)m8-HLH transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with E(spl)m5-HLH transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650 negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | non-traceable author statement imaginal disc-derived wing margin morphogenesis ; GO:0008587 | non-traceable author statement sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement ectoderm development ; GO:0007398 | traceable author statement mesoderm development ; GO:0007498 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype" - "CG8365, E(spl)m8, m8, Su(H)[[m8]], E(spl)-m8, En(spl), E(spl)bHLH, e(spl), En(spl)-C, E(spl) m8, E(spl)M8, clone 1.71, Hes, l(3)96Fd, anon-EST:Liang-1.71, E(spl), HLHm8, M8, E(spl)-C, Espl, bHLHb36, E(Spl), E(spl)m8-HLH, E(spl)-M8" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8365 11-Aug-17 DroID_v2017_08 "Drer\her1, Drer\hey2, Drer\her13, Drer\her15.2, Drer\her3, Drer\her6, Drer\helt, Drer\heyl, Drer\hes2.2, Drer\bhlhe41, Drer\her4.3, Drer\her7, Drer\her5, Drer\her11, Drer\LOC100149863, Drer\her12, Drer\her8a, Drer\hey1, Drer\her15.1, Drer\her4.4, Drer\her2, Drer\hes2.1, Drer\hes6, Drer\bhlhe40, Drer\her8.2, Drer\her4.2, Drer\her9" Scer\PHO4 "Cele\hlh-27, Cele\lin-22, Cele\hlh-25" "Xtro\hes7.2, Xtro\hey2, Xtro\hes2, Xtro\hey1, Xtro\bhlhe40, Xtro\hes3.3, Xtro\hes1, Xtro\bhlhe41, Xtro\hes7.1, Xtro\hes6.1, Xtro\hes4" "Mmus\Helt, Mmus\Hey2, Mmus\Bhlhe40, Mmus\Hes6, Mmus\Bhlhe41, Mmus\Heyl, Mmus\Hey1, Mmus\Hes3, Mmus\Hes5, Mmus\Hes7, Mmus\Hes2, Mmus\Hes1" "Hsap\HES6, Hsap\HEYL, Hsap\HES4, Hsap\HES1, Hsap\HEY1, Hsap\HES5, Hsap\HELT, Hsap\HES7, Hsap\BHLHE40, Hsap\HEY2, Hsap\HES3, Hsap\HES2, Hsap\BHLHE41" " embryonic stage | stage 11-12 , embryonic stage | stage 5 , embryonic stage , embryonic stage | 2-10 hr , embryonic stage | stage 10 , embryonic stage | stage 11-14 , embryonic stage | stage 7-11 , embryonic stage | stage 11 " " mesoderm

, organism | striped

, ventral neurogenic region

, larval brain

, embryonic central nervous system

, posterior midgut proper primordium

, stomatogastric nervous system | primordium

, embryonic optic lobe primordium

, peripheral nervous system

, ectoderm

, supraesophageal ganglion

, mesectoderm

, epidermis | restricted

" "lethal,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,neurogenic phenotype,cell lethalcell lethal,somatic clone,viable,dominant,neuroanatomy defective" "scutellar bristle,ectopic,scutum & macrochaeta & adult-537.4,adult abdomen & macrochaeta-537.4,adult head & macrochaeta-537.4,eye,macrochaeta | ectopic & scutellum455.2,socket,nervous system,chaeta & mesothoracic tergum,external sensory organ precursor cell,morphogenetic furrow,muscle founder cell,embryonic/larval somatic muscle,peripheral nervous system,anterior orbital bristle,postvertical bristle,interocellar bristle,crossvein,central nervous system,macrochaeta,microchaeta,wing vein,wing margin bristle,scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutum & macrochaetah-1J3,embryonic epidermis,macrochaeta & scutellum455.2,interommatidial bristle,somatic clone,epidermis,mesothoracic tergum,corpus cardiacum primordium,adult peripheral nervous system,microchaeta & mesothoracic tergum,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,ommatidium,eye photoreceptor cell,embryonic neuroblast,supernumerary,germline clone,embryonic/larval corpus cardiacum,eo neuron,dorsal triple row,chemosensory ventral triple row bristle,campaniform sensillum of anterior crossvein,campaniform sensillum L3-2 of wing vein L3,campaniform sensillum L3-3 of wing vein L3,chordotonal organ precursor cell & ventral thoracic disc-109-68,chaeta,external sensory organ,neuroblast" FBgn0003254 rib ribbon http://flybase.org/reports/FBgn0003254 FBgn0034424 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "open tracheal system development ; GO:0007424 | non-traceable author statement protein localization ; GO:0008104 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype membrane organization ; GO:0061024 | traceable author statement dorsal closure ; GO:0007391 | non-traceable author statement cell migration ; GO:0016477 | traceable author statement regulation of cell shape ; GO:0008360 | traceable author statement regulation of Malpighian tubule diameter ; GO:0035297 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement salivary gland development ; GO:0007431 | traceable author statement dorsal closure ; GO:0007391 | traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 central nervous system development ; GO:0007417 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement cytoskeleton organization ; GO:0007010 | traceable author statement tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | traceable author statement salivary gland morphogenesis ; GO:0007435 | non-traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement "rib, CG7230, gene 5, fus1, RIB" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR007889:DNA binding HTH domain, Psq-type, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR009057:Homeobox domain-like" CG7230 11-Aug-17 DroID_v2017_08 - - - - - "Hsap\ZBTB12, Hsap\ZBTB9" "lethal,recessive,cell polarity defective,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "gonad,gonadal sheath proper primordium,presumptive embryonic/larval tracheal system,embryonic/first instar larval cuticle,dorsal,denticle belt,denticle,trachea,embryonic/larval dorsal trunk,embryonic/larval dorsal branch,embryonic/larval ganglionic branch,embryonic/larval lateral trunk,embryonic/larval salivary gland,embryonic/larval salivary gland duct,embryonic epidermis,embryonic/larval hindgut,presumptive embryonic salivary gland,Malpighian tubule,dorsal closure embryo,midgut constriction,dorsal hair,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,embryonic/larval midgut,head,embryonic/larval salivary gland common duct,embryonic/larval tracheal system,peripheral nervous system precursor cluster,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,dorsal trunk primordium,embryo,embryonic head" FBgn0011604 Iswi Imitation SWI http://flybase.org/reports/FBgn0011604 "FBgn0010436, FBgn0066055" protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 nucleosome binding ; GO:0031491 | inferred from electronic annotation with InterPro:IPR015194 DNA helicase activity ; GO:0003678 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Chrac-16, Chrac-14 inferred from physical interaction with Chrac-14 DNA-dependent ATPase activity ; GO:0008094 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Chi inferred from physical interaction with tou nucleotide binding ; GO:0000166 | traceable author statement transcription factor binding ; GO:0008134 | inferred from physical interaction with pnr nucleosome-dependent ATPase activity ; GO:0070615 | inferred from direct assay DNA-dependent ATPase activity ; GO:0008094 | inferred from direct assay inferred from genetic interaction with His3 inferred from genetic interaction with His4 ATP binding ; GO:0005524 | inferred from sequence or structural similarity with SGD:S000005816 protein binding ; GO:0005515 | inferred from physical interaction with Acf" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype nucleosome positioning ; GO:0016584 | inferred from direct assay sperm chromatin decondensation ; GO:0035041 | inferred from mutant phenotype nucleosome mobilization ; GO:0042766 | inferred from direct assay chromatin remodeling ; GO:0006338 | traceable author statement nuclear speck organization ; GO:0035063 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype nucleosome assembly ; GO:0006334 | inferred from direct assay ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from genetic interaction with EcR ATP-dependent chromatin remodeling ; GO:0043044 | inferred from direct assay chromatin assembly or disassembly ; GO:0006333 | inferred from direct assay sperm chromatin condensation ; GO:0035092 | inferred from mutant phenotype chromatin assembly or disassembly ; GO:0006333 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from sequence or structural similarity with SGD:S000005816 positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement nucleosome mobilization ; GO:0042766 | traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype" CHRAC ; GO:0008623 | inferred from direct assay NURF complex ; GO:0016589 | traceable author statement CHRAC ; GO:0008623 | non-traceable author statement brahma complex ; GO:0035060 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay ISWI-type complex ; GO:0031010 | inferred from direct assay CHRAC ; GO:0008623 | traceable author statement NURF complex ; GO:0016589 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with Trf2 ACF complex ; GO:0016590 | inferred from direct assay ACF complex ; GO:0016590 | non-traceable author statement polytene chromosome ; GO:0005700 | inferred from direct assay nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay RSF complex ; GO:0031213 | inferred from physical interaction with CG8677 ACF complex ; GO:0016590 | traceable author statement polytene chromosome ; GO:0005700 | colocalizes_with inferred from direct assay "ISWI, NURF, CG8625, ACF, iswi, p140/ISWI, p140, dNURF, CHRAC, dISWI, dCHRAC, SWI, ISW, NURF-140, anon-EP1279744.124, Nurf-140, Iswi, NURF 140" "IPR000330:SNF2-related, N-terminal domain, IPR001005:SANT/Myb domain, IPR001650:Helicase, C-terminal, IPR009057:Homeobox domain-like, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR015194:ISWI, HAND domain, IPR015195:SLIDE domain, IPR017884:SANT domain, IPR029915:ISWI family, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020838:DBINO domain" CG8625 11-Aug-17 DroID_v2017_08 "Drer\chd1l, Drer\smarca1, Drer\smarca5" "Scer\IRC5, Scer\ISW2, Scer\ISW1" "Cele\isw-1, Cele\chd-3, Cele\let-418" "Xtro\smarca1, Xtro\smarca5" "Mmus\Chd1l, Mmus\Chd1, Mmus\Smarca5, Mmus\Smarca1" "Hsap\SMARCA1, Hsap\SMARCA5, Hsap\CHD1L" " embryonic stage | stage >=13 , embryonic stage--pupal stage , embryonic stage | stage <13 , adult stage | female " " gonad

, organism

, embryonic central nervous system

" embryonic stage -- adult stage "wild-type,lethal,lethal - all die before end of larval stage,some die during larval stage,recessive,female sterile,tumorigenic,visible,somatic clone,eye color defective,mitotic cell cycle defective,heat sensitive,non-enhancer of variegation,non-suppressor of variegation,viable,locomotor rhythm defective" "hemocyte,supernumerary,wing disc,polytene chromosome | male, with Iswi1,dorsocentral bristle,ovariole,germline clone,genitalia,somatic clone,adult head,adult thoracic segment,polytene chromosome,embryonic/larval hemocyte,female germline stem cell,follicle stem cell,X chromosome | male,eye,ommatidium,eye photoreceptor cell,polytene chromosome | male limited,condensed chromosome, with IswiK159R.UAS.TIvirHA1, da.G32,polytene chromosome | male, with Iswi2,polytene chromosomeey.PH,mechanosensory chaeta,euchromatinda.G32,condensed chromosomeda.G32,condensed chromosome, with Iswi2, da.G32,embryonic/larval brain,mesothoracic tergum" DRSC07446 EK -1.287038471 -0.637395978 -2.333316161 0.205063746 0.459351224 1.804933101 FBgn0001942 eIF4A eukaryotic translation initiation factor 4A http://flybase.org/reports/FBgn0001942 "FBgn0013406, FBgn0013523, FBgn0015864, FBgn0022247, FBgn0024969, FBgn0062252" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD:S000003674 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity translational initiation ; GO:0006413 | inferred from biological aspect of ancestor with PANTHER:PTN000620029 oogenesis ; GO:0048477 | inferred from genetic interaction with bam instar larval development ; GO:0002168 | traceable author statement centrosome organization ; GO:0051297 | inferred from mutant phenotype imaginal disc growth ; GO:0007446 | traceable author statement cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype inferred from genetic interaction with bam RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 pole cell formation ; GO:0007279 | inferred from genetic interaction with tud inferred from genetic interaction with vas mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype" centrosome ; GO:0005813 | inferred from direct assay eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity P granule ; GO:0043186 | inferred from direct assay "eIF4A, Dm-eIF4A, eif4A, Eif-4a, EIF-4A, DmRH2, CG9075, eIF-4A, EiF4A, l(2L)162, eif-4a, 2439, l(2)k01501, l(2)gdh-4, Su(dpp)YE9, l(2)26Ac, l(2)162, l(2)02439, anon26A, anon-26Aa, Eif4a, eIF-4a, eIF4a, eif4a, EIF4A, eIF-4a-I, eIF 4A, 9075, deIF4A, eIF4A-I, eIF4AI, L(2L)162, pecan, EIF-4a, eiF4A" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9075 11-Aug-17 DroID_v2017_08 "Drer\eif4a1b, Drer\eif4a2, Drer\eif4a3, Drer\eif4a1a" "Scer\TIF2, Scer\TIF1, Scer\FAL1" "Cele\F57B9.3, Cele\inf-1, Cele\F33D11.10, Cele\Y65B4A.6" "Xtro\eif4a3, Xtro\eif4a1, Xtro\eif4a2" "Mmus\Eif4a3, Mmus\Eif4a2, Mmus\Eif4a1" "Hsap\EIF4A1, Hsap\EIF4A3, Hsap\EIF4A2" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,mitotic cell cycle defective,partially lethal - majority die,decreased cell number,germline clone,developmental rate defective,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage" "female germline stem cell,germline clone,intersegmental nerve,anterior fascicle & synapse,embryonic/larval salivary gland,wing disc,amnioserosa,eye,egg chamber,oocyte,centrosome | germline clone,head,cuticle,parasegment 1,parasegment 2,parasegment 3,parasegment 4,parasegment 5,parasegment 6,parasegment 7,parasegment 8,parasegment 9,parasegment 10,parasegment 11,parasegment 12,parasegment 13,parasegment 14,parasegment 15,cephalopharyngeal skeleton,embryonic/first instar larval cuticle" DRSC03526 IEK -1.723586074 -1.691496907 -6.041652709 -6.557148602 1.8586471 1.051560475 FBgn0001404 egh egghead http://flybase.org/reports/FBgn0001404 - protein_coding_gene "beta-1,4-mannosyltransferase activity ; GO:0019187 | inferred from direct assay" "peripheral nervous system neuron development ; GO:0048935 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype regulation of oviposition ; GO:0046662 | inferred from mutant phenotype morphogenesis of follicular epithelium ; GO:0016333 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | inferred from mutant phenotype glycosphingolipid biosynthetic process ; GO:0006688 | inferred from direct assay optic lobe placode formation ; GO:0001744 | inferred from mutant phenotype ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype maintenance of polarity of follicular epithelium ; GO:0042248 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001047798 "CG9659, EG:BACR25B3.8, zw4, l(1)zw4, zw-4, ZW-4, l(1)3Ae, egh, beta1,4ManT, Egh" "IPR001173:Glycosyltransferase 2-like, IPR027389:Beta-1,4-mannosyltransferase Bre-3/Egh, IPR029044:Nucleotide-diphospho-sugar transferases" CG9659 11-Aug-17 DroID_v2017_08 - - Cele\bre-3 - - - " adult stage | female && oogenesis stage , embryonic stage | 0-2 hr , adult stage && oogenesis stage | stage S10 " " germarium region 2a && germline cell

, nurse cell

, germarium region 2b && germline cell

" "viable,female sterile,behavior defective,courtship behavior defective,male,partially lethal - majority die,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,germline clone,maternal effect,neurogenic phenotype,neuroanatomy defective,hyperplasia,lethal - all die before end of P-stage,some die during pharate adult stage,visible,heat sensitive" "ovary,eye,germline cell,oocyte,precursor,nurse cell,first optic chiasma,photoreceptor cell,ventral nerve cord,macrochaeta,dorsal appendage,germline clone,presumptive embryonic/larval nervous system,follicle cell,basal stalk,embryonic/larval midgut,nervous system,egg chamber,maternal effect,egg,female reproductive system,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina plexus,embryonic/larval peripheral nervous system,larval abdominal segment 9,plasmatocyte,ectopic,subperineurial glial cell,supernumerary,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal tergite 5,abdominal tergite 6,abdominal tergite 7,wing vein,embryonic/larval optic neuropil,lamina anlage,lobula,lamina anlage glial cell,lobula & neuron,somatic clone,denticle belt,procephalic segment" DRSC18771 I 2.854196427 0.311087233 0.664995989 -0.85816519 0.366931916 0.264136253 FBgn0003896 tup tailup http://flybase.org/reports/FBgn0003896 "FBgn0002017, FBgn0015395" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Chi RNA polymerase II activating transcription factor binding ; GO:0001102 | inferred from physical interaction with pnr" terminal region determination ; GO:0007362 | inferred from genetic interaction with tor heart development ; GO:0007507 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype negative regulation of sequence-specific DNA binding transcription factor activity ; GO:0043433 | inferred from direct assay amnioserosa maintenance ; GO:0046665 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype notum cell fate specification ; GO:0035310 | inferred from mutant phenotype head involution ; GO:0008258 | non-traceable author statement chaeta development ; GO:0022416 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype lymph gland development ; GO:0048542 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor regulation of gene expression ; GO:0010468 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Isl, CG10619, isl, islet, l(2)E41, l(2)37Aa, tup, Tup, Islet, TUP" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001781:Zinc finger, LIM-type, IPR009057:Homeobox domain-like" CG10619 11-Aug-17 DroID_v2017_08 "Drer\isl2b, Drer\isl2a, Drer\isl1, Drer\isl1l" - Cele\lim-7 "Xtro\isl1, Xtro\isl2" "Mmus\Isl1, Mmus\Isl2" "Hsap\ISL1, Hsap\ISL2" " embryonic stage | stage 10-16 , embryonic stage | stage >=12 , embryonic stage | stage 10 , embryonic stage | stage 16 " " embryonic/larval dorsal vessel

, embryonic brain | restricted

, amnioserosa

, pharyngeal muscle

, foregut primordium

, ventral nerve cord | restricted

, larval alary muscle

, embryonic/larval pharynx | precursor

" " embryonic stage | stage 16 , embryonic stage | stage 10 , embryonic stage | stage 12 , embryonic stage | stage 10-16 " " pharyngeal muscle

, embryonic/larval pharynx | precursor

, embryonic brain | restricted

, embryonic/larval dorsal vessel

, larval alary muscle

, amnioserosa

, ventral nerve cord | restricted

" "viable,partially lethal - majority die,recessive,visible,partially lethal - majority live,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,somatic clone,lethal,partially,neurophysiology defective" "dorsocentral bristle,supernumerary,scutellar bristle,external sensory organ precursor cell,extended germ band embryo,amnioserosa,dorsal closure embryo,embryonic head,cephalopharyngeal skeleton,dorsal bridge,vertical bridge,embryonic/first instar larval cuticle,dorsal,adult antennal lobe projection neuron DL1 adPN,adult antennal lobe projection neuron VM7 adPN,adult antennal lobe projection neuron VA3 adPN,adult antennal lobe projection neuron VM2 adPN,adult antennal lobe projection neuron DM6 adPN,adult antennal lobe projection neuron VA1v adPN,antennal lobe glomerulus DL1,antennal lobe glomerulus VM7,antennal lobe glomerulus VA3,antennal lobe glomerulus VM2,antennal lobe glomerulus DM6,adult antennal lobe projection neuron VA7m lPN,adult antennal lobe projection neuron VA5 lPN,antennal lobe glomerulus VA5,adult antennal lobe projection neuron DM5 lPN,antennal lobe glomerulus DM5,adult antennal lobe projection neuron DM2 lPN,antennal lobe glomerulus DM2,adult antennal lobe projection neuron DM1 lPN,antennal lobe glomerulus DM1,subesophageal ganglion,antennal lobe glomerulus DA1,antennal lobe glomerulus VA1v,intrinsic neuron,interneuron,motor neuron,bipolar dendrite neuron,serotonergic neuron,dopaminergic neuron,intersegmental nerve,transverse nerve,somatic clone,adult cuticle,scutum,scutellum,wing disc,metathoracic laterotergite,sensillum campaniformium,ectopic,mesothoracic tergum,wing sclerite,tegula,macrochaeta,sensillum trichodeum,wing,thorax,interneuron | embryonic stage,motor neuron | embryonic stage,tarsal segment 4,femur,tibia,unguis,metatarsus,mesothoracic pleurum,A1-7 dorsal acute muscle 3,A1-7 dorsal acute muscle 2,eye,mesothoracic bristle" FBgn0052179 Krn Keren http://flybase.org/reports/FBgn0052179 protein_coding_gene epidermal growth factor receptor binding ; GO:0005154 | inferred from biological aspect of ancestor with PANTHER:PTN000960795 positive regulation of epidermal growth factor-activated receptor activity ; GO:0045741 | inferred from mutant phenotype inferred from genetic interaction with Egfr MAPK cascade ; GO:0000165 | inferred from direct assay positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from genetic interaction with S border follicle cell migration ; GO:0007298 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from genetic interaction with S epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement olfactory learning ; GO:0008355 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay extracellular region ; GO:0005576 | inferred from biological aspect of ancestor with PANTHER:PTN000960795 "keren/spitz2, keren, Ker, CT19073, gritz, CG8056, CG32179, Krn, krn, s-krn, skrn" "IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site" CG32179 11-Aug-17 DroID_v2017_08 Drer\nrg1 - - - Mmus\Nrg1 Hsap\NRG1 "partially lethal - majority die,lethal,increased cell number,mitotic cell cycle defective,cell polarity defective,viable,fertile,some die during pupal stage,learning defective,RU486 conditional" "embryonic/larval hemocyte | third instar larval stage,midgut,wing,dorsal appendage,ectopic,denticle belt,cephalopharyngeal skeleton,adult midgut precursor cell | third instar larval stage,enterocyte,midgut interstitial cell,intestinal stem cell,wing vein,denticle,border follicle cell,somatic clone,eye,ommatidium,adult midgut precursor cell,cone cell,supernumerary" DRSC11202 IK -0.154430958 -1.878950925 0.504463465 0.461148564 1.540496675 -0.220926733 FBgn0038067 CG11598 - http://flybase.org/reports/FBgn0038067 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483 lipase activity ; GO:0016298 | inferred from sequence or structural similarity" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 lipid metabolic process ; GO:0006629 | inferred from sequence or structural similarity multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay CG11598 "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG11598 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\YEH1, Scer\TGL1, Scer\YEH2" "Cele\lipl-7, Cele\lipl-6, Cele\lipl-1, Cele\lipl-5, Cele\lipl-2, Cele\lipl-8, Cele\lipl-3, Cele\lipl-4" Xtro\lipa "Mmus\Lipo4, Mmus\Lipo2, Mmus\Lipf, Mmus\Lipo1, Mmus\Lipo3, Mmus\Lipm, Mmus\Lipk, Mmus\Lipn, Mmus\Lipa" "Hsap\LIPN, Hsap\LIPF, Hsap\LIPK, Hsap\LIPA, Hsap\LIPJ, Hsap\LIPM" "viable,fertile" DRSC14331 EK -0.839313893 0.381968466 1.902366818 0.142274934 -1.185616628 -2.018548395 FBgn0003328 scb scab http://flybase.org/reports/FBgn0003328 "FBgn0010481, FBgn0011707, FBgn0013742, FBgn0014404, FBgn0041840" protein_coding_gene cell adhesion molecule binding ; GO:0050839 | traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Itgbn protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with mys receptor activity ; GO:0004872 | traceable author statement "negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from genetic interaction with Fak phagocytosis ; GO:0006909 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement midgut development ; GO:0007494 | traceable author statement learning or memory ; GO:0007611 | non-traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype cell adhesion ; GO:0007155 | traceable author statement behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from sequence or structural similarity with mys calcium-dependent cell-matrix adhesion ; GO:0016340 | inferred from sequence or structural similarity heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | traceable author statement dorsal trunk growth, open tracheal system ; GO:0035001 | inferred from mutant phenotype cell-matrix adhesion ; GO:0007160 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype oocyte growth ; GO:0001555 | inferred from mutant phenotype negative regulation of cell migration ; GO:0030336 | inferred from mutant phenotype locomotion ; GO:0040011 | non-traceable author statement larval heart development ; GO:0007508 | inferred from mutant phenotype short-term memory ; GO:0007614 | traceable author statement memory ; GO:0007613 | non-traceable author statement salivary gland development ; GO:0007431 | inferred from mutant phenotype apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype memory ; GO:0007613 | traceable author statement cell migration ; GO:0016477 | traceable author statement calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity wound healing ; GO:0042060 | inferred from mutant phenotype olfactory learning ; GO:0008355 | non-traceable author statement pericardium morphogenesis ; GO:0003344 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from direct assay integrin complex ; GO:0008305 | inferred from physical interaction with mys plasma membrane ; GO:0005886 | inferred from sequence or structural similarity integrin complex ; GO:0008305 | inferred from sequence or structural similarity integrin complex ; GO:0008305 | non-traceable author statement focal adhesion ; GO:0005925 | inferred from sequence or structural similarity integrin complex ; GO:0008305 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay basal plasma membrane ; GO:0009925 | inferred from direct assay "scb, alphaPS3, E(sev-cycE)[e93], PS3, vol, alpha[[PS3]], alpha-PS3, Vol, CG8095, CT36929, CT21280, Dm0620, aPS3, E(Sev-CycE)E93, l(2)01288, alphaInt3, scab, beta[[PS3], ItgaPS3, ITA3" "IPR018184:Integrin alpha chain, C-terminal cytoplasmic region, conserved site, IPR000413:Integrin alpha chain, IPR013519:Integrin alpha beta-propellor, IPR013649:Integrin alpha-2, IPR032695:Integrin domain" CG8095 11-Aug-17 DroID_v2017_08 "Drer\itga4, Drer\zmp:0000001082, Drer\itga3a, Drer\itgae.1, Drer\itga6b, Drer\si:dkey-32n7.4, Drer\itgae.2, Drer\itga6a, Drer\itga11a, Drer\itga2.2, Drer\itga9, Drer\itgam, Drer\itga3b, Drer\itga6l, Drer\itga1, Drer\itga10, Drer\itga11b" - Cele\ina-1 "Xtro\itga4, Xtro\itga9, Xtro\itga2, Xtro\itga11, Xtro\itga1" "Mmus\Itga1, Mmus\Itga9, Mmus\Itgae, Mmus\Itgax, Mmus\Itgal, Mmus\Itga10, Mmus\Itga11, Mmus\Itga7, Mmus\Itga4, Mmus\Itgad, Mmus\Itga3, Mmus\Itgam, Mmus\Itga6, Mmus\Itga2" "Hsap\ITGA11, Hsap\ITGA4, Hsap\ITGA3, Hsap\ITGAD, Hsap\ITGA7, Hsap\ITGAX, Hsap\ITGA9, Hsap\ITGAE, Hsap\ITGA2, Hsap\ITGAL, Hsap\ITGAM, Hsap\ITGA10, Hsap\ITGA1, Hsap\ITGA6" " embryonic stage | late , embryonic stage | stage 16 , embryonic stage -- adult stage , embryonic stage | stage 8-14 , embryonic stage | stage 13-17 , embryonic stage | stage 9 , embryonic stage | stage 11 , embryonic stage | stage 15-17 , embryonic stage && pupal stage && adult stage , embryonic stage | stage 15 , embryonic stage | early , embryonic stage | stage 11-15 , embryonic stage | stage 7 , embryonic stage | stage 15,16 " " gastric caecum

, midgut constriction

, amnioserosa

, embryonic/larval salivary gland

, visceral mesoderm | presumptive

, tracheal pit

, posterior midgut proper primordium

, embryonic/larval anterior spiracle

, embryonic/larval transverse connective

, antenno-maxillary complex

, anterior midgut proper primordium

, ventral nerve cord | restricted

, embryonic/larval proventriculus

, embryonic/larval dorsal vessel

,

ubiquitous , embryonic salivary gland

, embryonic/larval salivary gland duct

, embryonic/larval dorsal trunk

, amnioproctodeal invagination

, embryonic/larval midgut

, mesectoderm

" adult stage " mushroom body alpha-lobe

, mushroom body gamma-lobe

, mushroom body beta-lobe

, mushroom body

, cell body &&of mushroom body

, calyx of mushroom body

, ellipsoid body

" "partially lethal - majority die,lethal,recessive,viable,fertile,learning defective,memory defective,dominant,neurophysiology defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal - all die before end of larval stage,some die during larval stage,semidominant,visible,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,hyperactive,conditional,chemical resistant" "embryonic/larval hemocyte | third instar larval stage,embryonic dorsal epidermis,dorsal closure embryo,anterior fascicle & synapse,intersegmental nerve,extended germ band embryo,pericardial cell,dorsal superficial trachea,embryonic/larval salivary gland,fascicle,embryo,dorsal,neuromuscular junction,bouton,supernumerary,axon terminus | supernumerary,germline clone,germ band,embryonic heart cardioblast,embryonic/first instar larval cuticle,wing vein,somatic clone,amnioserosa,tracheal branch primordium,cell leading edge,filamentous actin,stage 13 embryo,stage 14 embryo,stage 15 embryo,embryonic hemocyte" FBgn0025641 DAAM Dishevelled Associated Activator of Morphogenesis http://flybase.org/reports/FBgn0025641 FBgn0027752 protein_coding_gene "Rho GTPase binding ; GO:0017048 | inferred from electronic annotation with InterPro:IPR010473 actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR010472, InterPro:IPR010473 actin binding ; GO:0003779 | inferred from sequence or structural similarity" "positive regulation of sarcomere organization ; GO:0060298 | inferred from genetic interaction with Act88F inferred from genetic interaction with Tm2 positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype inferred from genetic interaction with Act88F inferred from genetic interaction with Tm2 regulation of tube architecture, open tracheal system ; GO:0035152 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from genetic interaction with Frl regulation of axonogenesis ; GO:0050770 | inferred from direct assay regulation of filopodium assembly ; GO:0051489 | inferred from direct assay muscle thin filament assembly ; GO:0071689 | inferred from genetic interaction with Act88F inferred from genetic interaction with Tm2 axon guidance ; GO:0007411 | inferred from mutant phenotype" striated muscle thin filament ; GO:0005865 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay sarcoplasm ; GO:0016528 | inferred from direct assay axonal growth cone ; GO:0044295 | inferred from direct assay "dDAAM, CG14622, EG:114D9.2, anon-EST:Posey148, DAAM, daam, Daam, dDaam" "IPR010472:Formin, FH3 domain, IPR014768:Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425:Formin, FH2 domain, IPR014767:Diaphanous autoregulatory (DAD) domain, IPR011989:Armadillo-like helical, IPR027650:Disheveled-associated activator of morphogenesis 1, IPR010473:Formin, GTPase-binding domain, IPR016024:Armadillo-type fold" CG14622 11-Aug-17 DroID_v2017_08 "Drer\fmnl2a, Drer\grid2ipb, Drer\fhdc4, Drer\daam2, Drer\daam1b, Drer\fnbp4, Drer\inf2, Drer\daam1a" "Scer\BNI1, Scer\BNR1" "Cele\fozi-1, Cele\frl-1, Cele\cyk-1, Cele\daam-1" "Xtro\inf2, Xtro\daam1, Xtro\fmnl1" "Mmus\Fmnl3, Mmus\Fmnl2, Mmus\Diaph3, Mmus\Daam1, Mmus\Inf2, Mmus\Diaph1, Mmus\Daam2, Mmus\Grid2ip, Mmus\Fnbp4, Mmus\Fmnl1, Mmus\Diaph2" "Hsap\GRID2IP, Hsap\DAAM1, Hsap\DIAPH3, Hsap\INF2, Hsap\FMNL3, Hsap\FMNL1, Hsap\DIAPH2, Hsap\FMNL2, Hsap\DIAPH1, Hsap\FNBP4, Hsap\DAAM2" "neuroanatomy defective,viable,lethal - all die before end of larval stage,some die during larval stage,flightless,fertile,locomotor behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,partially lethal - majority die" "ventral nerve cord,neurite,axon,taenidial fold,embryonic/larval tracheal system,indirect flight muscle,myofibril, with DAAMEx1, Dcr-2UAS.cDa, UH3,striated muscle thin filament, with DAAMEx1, Dcr-2UAS.cDa, UH3,striated muscle myosin thick filament, with DAAMEx1, Dcr-2UAS.cDa, UH3,sarcomere, with DAAMEx1, Dcr-2UAS.cDa, UH3,M band, with DAAMEx1, Dcr-2UAS.cDa, UH3,Z disc, with DAAMEx1, Dcr-2UAS.cDa, UH3,embryonic/larval somatic muscle | late third instar larval stage,A1-7 ventral longitudinal muscle 3 | late third instar larval stage,sarcomere | late third instar larval stageMef2.PU,filamentous actin & tracheal fusion cell, with DAAMC.UAS.PT, btl.PS,filamentous actin & tracheal fusion cell, with DAAMUAS.PT.cMa, btl.PS,filamentous actin & tracheal fusion cellbtl.PS,filamentous actin & tracheolar cellbtl.PS,neuropil | embryonic stage,fascicle | embryonic stage,commissure | embryonic stage,myofibril,sarcomere,embryonic/larval trachea,neuropil,fascicle,connective,lateral longitudinal fascicle,embryo,filopodium,myofibril, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,striated muscle thin filament, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,striated muscle myosin thick filament, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,sarcomere, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,M band, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,Z disc, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, UH3,embryonic/larval somatic muscle,A1-7 ventral longitudinal muscle 3,sarcomere | late third instar larval stage,filamentous actin,embryonic/larval cuticle" FBgn0002914 Myb Myb oncogene-like http://flybase.org/reports/FBgn0002914 - protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay transcription factor activity, RNA polymerase II transcription factor recruiting ; GO:0001135 | inferred from biological aspect of ancestor with PANTHER:PTN000067606 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000067606 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement DNA binding ; GO:0003677 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000067606" spindle organization ; GO:0007051 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype positive regulation of G2/M transition of mitotic cell cycle ; GO:0010971 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from direct assay chromosome condensation ; GO:0030261 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype positive regulation of transcription involved in G2/M transition of mitotic cell cycle ; GO:0090282 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype centrosome cycle ; GO:0007098 | inferred from mutant phenotype positive regulation of mitotic cell cycle ; GO:0045931 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | traceable author statement regulation of mitotic nuclear division ; GO:0007088 | inferred from direct assay regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype inferred from genetic interaction with nej Golgi organization ; GO:0007030 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype Myb complex ; GO:0031523 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear euchromatin ; GO:0005719 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "dMyb, Dm-Myb, DmMyb, dmyb, MYB, myb, Dm myb, dmMYB, c-Myb, p85, DMyb, Dm-myb, CG9045, Dm Myb, D-myb, DmMYB, c-myb, l(1)XVI, Myb, Dmyb" "IPR001005:SANT/Myb domain, IPR009057:Homeobox domain-like, IPR015395:C-myb, C-terminal, IPR017877:Myb-like domain, IPR017930:Myb domain" CG9045 11-Aug-17 DroID_v2017_08 "Drer\mybl1, Drer\myb, Drer\mybl2a, Drer\dmtf1, Drer\mybl2b" "Scer\BAS1, Scer\REB1, Scer\NSI1" Cele\snpc-4 "Xtro\mybl2, Xtro\myb" "Mmus\4932411N23Rik, Mmus\Dmtf1, Mmus\Mybl2, Mmus\Mybl1, Mmus\Myb, Mmus\Snapc4" "Hsap\MYBL1, Hsap\DMTF1, Hsap\MYB, Hsap\SNAPC4, Hsap\MYBL2" " embryonic stage | early , pupal stage | early , pupal stage , larval stage | third instar , adult stage && oogenesis stage , adult stage , embryonic stage | late , pupal stage--adult stage " " thoracico-abdominal ganglion

, nervous system

, ovary

, imaginal disc

, brain

, testis

, oocyte

, adult brain

, nurse cell

, embryonic central nervous system

, ventral nerve cord

" "visible,wild-type,dominant,mitotic cell cycle defective,increased cell death,lethal,recessive,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,maternal effect,cytokinesis defective,cell cycle defective,viable" "adult cuticle,eye,ommatidium,eye photoreceptor cell,eye disc,rhabdomere,histoblast,abdomen,cell cyclesd72a),mitotic prophasesd72a),centrosomesd72a),mitosis & nuclear chromosomesd72a),mitotic cell cyclesd72a),wing hair,microchaeta & adult abdomen,cell cycle,mitotic prophase,centrosome,mitosis & nuclear chromosome,mitotic cell cycle,wing,ectopic,macrochaeta,adult abdominal segment,wing & nucleus,wing & cell,precursor,supernumerary,nuclear chromosome,embryo,microchaeta,wing sensillum,adult abdominal sensillum,wing vein,wing & macrochaeta,maternal effect,adult abdomen,microchaeta & wing | maternal effect,macrochaeta & wing | maternal effect,G2 phase,mitotic M phase,S phase,mitotic anaphase,spindle,crystal cell,plasmatocyte,hemocyte & nucleus,embryonic/larval lymph gland,dorsal appendage,somatic clone,chorion | somatic clone,neuroblast,chromosome,condensed nuclear chromosome,wing disc,haltere disc,mitotic cell cycleen-e16E,mitotic cell cyclesd-SG29.1,embryonic/larval salivary gland,mitotic cell cyclefkh.PB,ventral thoracic disc" DRSC20260 IE 2.662936411 -1.332375036 2.493257326 -2.809530054 0.927742074 0.957135508 FBgn0005775 Con Connectin http://flybase.org/reports/FBgn0005775 FBgn0004358 protein_coding_gene - homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | traceable author statement axonal fasciculation ; GO:0007413 | traceable author statement synaptic target attraction ; GO:0016200 | traceable author statement cell surface ; GO:0009986 | inferred from direct assay axonal growth cone ; GO:0044295 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay plasma membrane ; GO:0005886 | traceable author statement "CON, con, CT1840, conn, anon-64C, Ubx-t35, CG7503, Con" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR003591:Leucine-rich repeat, typical subtype, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG7503 11-Aug-17 DroID_v2017_08 "Drer\lrrtm4l1, Drer\LOC563710, Drer\lrrtm2, Drer\lrrtm1" - - "Xtro\LOC100488256, Xtro\lrrtm1" "Mmus\Lrrtm4, Mmus\Lrrtm2, Mmus\Lrrtm1, Mmus\Lrrtm3" "Hsap\LRRTM4, Hsap\LRRTM3, Hsap\LRRTM1, Hsap\LRRTM2" " embryonic stage , embryonic stage | stage 11-14 , embryonic stage | stage 11-17 , embryonic stage | stage 10 " " visceral mesoderm

, abdominal 1--7 dorsal transverse muscle 1

, abdominal 1--7 lateral transverse muscle 2

, neuron

, somatic muscle

, abdominal 1--7 lateral transverse muscle 1

, larval sense organ &&of embryonic gnathal segment

, somatic mesoderm

, abdominal 1--7 lateral transverse muscle 3

, abdominal 1--7 lateral oblique muscle 1

, embryonic central nervous system | presumptive

, embryonic central nervous system | restricted

, visceral mesoderm | presumptive

, abdominal 1--7 lateral transverse muscle 4

, abdominal 1--7 ventral acute muscle 2

, abdominal 1 ventral acute muscle 3

" " embryonic stage , embryonic stage | late " " myoblast

, anterior commissure

, RP1 neuron

, abdominal 1--7 lateral transverse muscle 3

, interface glial cell

, muscle founder cell

, visceral mesoderm

, abdominal 1 ventral acute muscle 3

, abdominal 1--7 dorsal transverse muscle 1

, peripheral glial cell 4

, larval muscle system

, abdominal 1--7 lateral transverse muscle 1

, abdominal 1--7 lateral transverse muscle 2

, abdominal 1--7 ventral acute muscle 2

, peripheral glial cell 3

, posterior commissure

, neuron

, longitudinal connective

, abdominal 1--7 lateral oblique muscle 1

, motor neuron

, abdominal 1--7 lateral transverse muscle 4

, midline glial cell

, VUM neuron

, peripheral glial cell 1

" "viable,female fertile,male fertile,neuroanatomy defective" "RP1 motor neuron,RP3 motor neuron,abdominal segmental nerve,abdominal ventral muscle,abdominal 1 ventral oblique muscle 4,abdominal 2 ventral oblique muscle 4,abdominal 3 ventral oblique muscle 4,abdominal 4 ventral oblique muscle 4,abdominal 5 ventral oblique muscle 4,abdominal 6 ventral oblique muscle 4,abdominal 7 ventral oblique muscle 4,abdominal 1 ventral oblique muscle 5,abdominal 2 ventral oblique muscle 5,abdominal 3 ventral oblique muscle 5,abdominal 4 ventral oblique muscle 5,abdominal 5 ventral oblique muscle 5,abdominal 6 ventral oblique muscle 5,abdominal 7 ventral oblique muscle 5,abdominal 2 ventral oblique muscle 6,abdominal 3 ventral oblique muscle 6,abdominal 4 ventral oblique muscle 6,abdominal 5 ventral oblique muscle 6,abdominal 6 ventral oblique muscle 6,abdominal 7 ventral oblique muscle 6,abdominal 1 ventral longitudinal muscle 1,abdominal 2 ventral longitudinal muscle 1,abdominal 3 ventral longitudinal muscle 1,abdominal 4 ventral longitudinal muscle 1,abdominal 5 ventral longitudinal muscle 1,abdominal 6 ventral longitudinal muscle 1,abdominal 7 ventral longitudinal muscle 1,abdominal 1 ventral longitudinal muscle 2,abdominal 2 ventral longitudinal muscle 2,abdominal 3 ventral longitudinal muscle 2,abdominal 4 ventral longitudinal muscle 2,abdominal 5 ventral longitudinal muscle 2,abdominal 6 ventral longitudinal muscle 2,abdominal 7 ventral longitudinal muscle 2" FBgn0000139 ash2 "absent, small, or homeotic discs 2" http://flybase.org/reports/FBgn0000139 FBgn0060470 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q94544 enzyme binding ; GO:0019899 | inferred from physical interaction with UniProtKB:P20659 inferred from physical interaction with UniProtKB:Q8IRW8 DNA binding ; GO:0003677 | inferred from direct assay transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000063846 histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000063846 imaginal disc development ; GO:0007444 | traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype pupal development ; GO:0035209 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from mutant phenotype negative regulation of histone phosphorylation ; GO:0033128 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of histone H3-K4 methylation ; GO:0051571 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype inferred from genetic interaction with kni inferred from genetic interaction with net inferred from genetic interaction with bs response to ecdysone ; GO:0035075 | inferred from direct assay pupal development ; GO:0035209 | traceable author statement histone H3-K4 methylation ; GO:0051568 | inferred from direct assay brain development ; GO:0007420 | traceable author statement MLL1/2 complex ; GO:0044665 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay MLL3/4 complex ; GO:0044666 | inferred from direct assay Set1C/COMPASS complex ; GO:0048188 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity inferred from direct assay "CG6677, l(3)112411, ash-2, ASH2, 1124/11, 291.8, l(3)S112411, mad, l(3)SG65, 703, ash2, Ash2" "IPR001870:B30.2/SPRY domain, IPR001965:Zinc finger, PHD-type, IPR003877:SPRY domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6677 11-Aug-17 DroID_v2017_08 Drer\ash2l Scer\BRE2 Cele\ash-2 Xtro\ash2l Mmus\Ash2l Hsap\ASH2L embryonic stage -- adult stage " larval stage | late , larval stage | third instar , larval stage--pupal stage " " embryonic/larval fat body

, embryonic/larval salivary gland

, imaginal disc

" "lethal,recessive,neuroanatomy defective,partially lethal - majority die,sterile,visible,some die during pharate adult stage,some die during immature adult stage,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,lethal - all die before end of prepupal stage,some die during prepupal stage,viable" "anterior fascicle & synapse,intersegmental nerve,adult mesothoracic segment,ectopic,adult prothoracic segment,wing,crossvein,wing margin,posterior,wing vein L3,wing vein L2,wing vein L5,wing vein,wing disc,wing margin bristle,wing & macrochaetaash18),macrochaeta,wing & macrochaeta,socket,thorax & macrochaetaash18),thorax & macrochaeta,proboscis,antenna,prothoracic segment,dorsal,prothoracic leg,haltere,metathoracic leg,genitalia,somatic clone,wing vein L1,wing vein L6,imaginal disc,wing cell,wing & sensillum campaniformium,capitellum & macrochaeta,capitellum,haltere pedicel,bellum,wing & sensillum campaniformiumash18),dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa" FBgn0003396 shn schnurri http://flybase.org/reports/FBgn0003396 "FBgn0010584, FBgn0013727, FBgn0043359" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 RNA polymerase II activating transcription factor binding ; GO:0001102 | inferred from physical interaction with Mad transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with protein_id:CAA35798.1 sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 RNA polymerase II transcription coactivator activity ; GO:0001105 | inferred from direct assay" "peripheral nervous system development ; GO:0007422 | non-traceable author statement transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement midgut development ; GO:0007494 | inferred from mutant phenotype multicellular organism development ; GO:0007275 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 negative regulation of cell proliferation ; GO:0008285 | non-traceable author statement wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 learning or memory ; GO:0007611 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement ectoderm development ; GO:0007398 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | non-traceable author statement negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inferred from genetic interaction with dpp wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 olfactory learning ; GO:0008355 | inferred from mutant phenotype" nucleus ; GO:0005634 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 "schnurri, shn, CG7734, Shn, quo, l(2)04738, SD06302, EP(2)2359, EP2359, BEST:SD06302, SHN, Schnurri" "IPR013087:Zinc finger C2H2-type, IPR003604:Matrin/U1-C-like, C2H2-type zinc finger, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR034729:Zinc finger CCHC HIVEP-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG7734 11-Aug-17 DroID_v2017_08 "Drer\hivep3a, Drer\si:ch211-216l23.1, Drer\znf831, Drer\hivep1, Drer\hivep2b, Drer\si:ch211-266d19.4, Drer\znf1004, Drer\hivep3, Drer\hivep2a, Drer\znf983" - "Cele\sma-9, Cele\T22C8.3" "Xtro\hivep2, Xtro\hivep1, Xtro\hivep3, Xtro\znf423, Xtro\znf507, Xtro\znf827" "Mmus\Hivep3, Mmus\Hivep2, Mmus\Zfp619, Mmus\Zfp423, Mmus\Zfp236, Mmus\Zfp827, Mmus\Zfp808, Mmus\Zfp831, Mmus\Hivep1, Mmus\Zfat, Mmus\Zfp729a" "Hsap\HIVEP2, Hsap\ZFAT, Hsap\ZNF831, Hsap\ZNF616, Hsap\ZNF423, Hsap\ZNF236, Hsap\ZNF91, Hsap\HIVEP3, Hsap\ZNF658, Hsap\ZNF827, Hsap\HIVEP1, Hsap\ZNF836, Hsap\ZFP62" " embryonic stage | stage 8-10 , embryonic stage | stage 14 , larval stage , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | stage 7-10 , embryonic stage | early , embryonic stage | stage >12 , embryonic stage | blastoderm , embryonic stage | cellular blastoderm , adult stage && oogenesis stage , embryonic stage | stage 10-12 , embryonic stage | stage 4,5 " " ectoderm | dorsal

, embryonic/larval pharynx

, imaginal disc

, parasegment 7 &&of endoderm

, mesoderm | presumptive

, mesoderm

,

ubiquitous , endoderm

,

dorsal , posterior embryonic/larval midgut

, visceral mesoderm &&of parasegment 6,7

, anterior embryonic/larval midgut

, gastric caecum

, nurse cell

, parasegment 4 &&of endoderm

, ovary

, endoderm &&of embryonic/larval midgut

, germarium

" embryonic stage | stage 14 " endoderm

, embryonic/larval foregut

" "circadian rhythm defective,heat sensitive,memory defective,visible,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,cytokinesis defective,viable" "scutellar bristle,eye,ommatidium,wing vein,embryonic epidermis,dorsal,female germline stem cell,germline clone,embryonic head,embryonic/first instar larval cuticle,denticle belt,embryo,filzkorper,embryonic dorsal epidermis,chordotonal organ,lateral,dorsal abdominal cluster,lateral abdominal cluster,presumptive embryonic/larval peripheral nervous system,fascicle,anterior fascicle & synapse,dorsal closure embryo,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,triple row,cell autonomous,somatic clone,double row,ectopic,cell non-autonomous,wing,anterior compartment,epidermis,germline cell,visceral mesoderm,Malpighian tubule,embryonic/larval midgut,midgut constriction,crystal cell,photoreceptor cell" DRSC07681 I -0.715378 -4.10910016 -1.138221484 -1.378545711 -0.225993233 -0.094700599 FBgn0000346 comt comatose http://flybase.org/reports/FBgn0000346 "FBgn0011678, FBgn0030463" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | traceable author statement" SNARE complex disassembly ; GO:0035494 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from genetic interaction with Dysb synaptic vesicle priming ; GO:0016082 | non-traceable author statement regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype synaptic vesicle fusion to presynaptic active zone membrane ; GO:0031629 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from expression pattern Golgi to lysosome transport ; GO:0090160 | inferred from mutant phenotype synaptic vesicle ; GO:0008021 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement terminal bouton ; GO:0043195 | inferred from direct assay neuromuscular junction of somatic muscle ; GO:0098527 | inferred from direct assay "NSF-1, dNSF-1, dnsf1, dNSF1, CG1618, NSF1, DmNSF, dNsf1, NSF, Nsf, com, dNSF, comt, Comt, CG 1618" "IPR003338:CDC48, N-terminal subdomain, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR004201:CDC48, domain 2, IPR009010:Aspartate decarboxylase-like domain, IPR029067:CDC48 domain 2-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1618 11-Aug-17 DroID_v2017_08 "Drer\nsfa, Drer\nsfb" Scer\SEC18 Cele\nsf-1 Xtro\nsf Mmus\Nsf Hsap\NSF " embryonic stage | late , adult stage , larval stage " embryonic central nervous system

"paralytic,heat sensitive,recessive,wild-type,neurophysiology defective,mating defective,bang sensitive,visual behavior defective,locomotor behavior defective,uncoordinated,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,germline clone,viable,short lived" "central nervous system,Golgi apparatus,Golgi stack | ectopic,embryonic/larval heart,synaptic vesicle | heat sensitive,retina,heat sensitive,dorsal medial muscle,Golgi stack,optic cartridge & synaptic vesicle,synapse,NMJ bouton" DRSC20319 E -0.537857346 0.163499496 0.836398183 -1.544403707 -0.957642723 -0.585018436 FBgn0004606 zfh1 Zn finger homeodomain 1 http://flybase.org/reports/FBgn0004606 FBgn0010733 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement" heart development ; GO:0007507 | non-traceable author statement nervous system development ; GO:0007399 | inferred from expression pattern pole cell migration ; GO:0007280 | traceable author statement mesoderm development ; GO:0007498 | inferred from expression pattern inferred from genetic interaction with sna inferred from genetic interaction with twi antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay gonad development ; GO:0008406 | traceable author statement germ cell migration ; GO:0008354 | traceable author statement motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype garland nephrocyte differentiation ; GO:0061321 | inferred from mutant phenotype hemocyte development ; GO:0007516 | inferred from mutant phenotype lymph gland development ; GO:0048542 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype somatic stem cell division ; GO:0048103 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Zfh-1, ZFH-1, zfh-1, Zfh1, zfl-1, l(3)00865, CG1322, zfh1, ZFH1, Zfh1a, zhf1" "IPR017970:Homeobox, conserved site, IPR013087:Zinc finger C2H2-type, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1322 11-Aug-17 DroID_v2017_08 "Drer\zeb2a, Drer\zeb1b, Drer\zeb2b, Drer\zeb1a, Drer\zgc:66443, Drer\znf1004" - "Cele\ZK686.5, Cele\zag-1" "Xtro\zeb1, Xtro\zeb2" "Mmus\Zfp853, Mmus\Zeb1, Mmus\Zfp787, Mmus\Zeb2, Mmus\Prdm16, Mmus\Mecom, Mmus\Zfp236" "Hsap\ZEB1, Hsap\MECOM, Hsap\ZNF853, Hsap\ZNF91, Hsap\ZNF236, Hsap\ZEB2, Hsap\ZNF787, Hsap\PRDM16" embryonic stage " embryonic/larval somatic muscle

, adult myoblast

, cardioblast

, embryonic/larval dorsal vessel

, larval visceral muscle

, central nervous system | restricted

, gonad

, mesoderm

, pole cell

" " embryonic stage , embryonic stage | stage 15-17 " " pole cell

, aCC neuron

, somatic muscle

, pericardial cell

, VUM neuron

, embryonic/larval dorsal vessel

, RP neuron

, GW neuron

, gonad

, central nervous system | restricted

, lateral ipsisegmental neuron

, cardioblast

, ventral intersegmental neuron

, adult myoblast

, visceral muscle

, mesoderm

" "lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,heat sensitive,wild-type,viable" "intersegmental nerve,abdominal segmental nerve,presumptive embryonic/larval central nervous system,heat sensitive,eye,macrochaeta & thorax | conditional ts,fat body/gonad primordium,gonad,precursor,heart primordium,germline cell,gonadal sheath proper primordium,embryonic/larval dorsal trunk,cyst progenitor cell,somatic clone,embryonic/larval dorsal vessel,embryonic/larval somatic muscle,pericardial cell,embryonic/larval pericardial cell,cardioblast,embryonic/larval lymph gland,hemocyte,embryonic somatic muscle,male,garland cell,A1-7 dorsal oblique muscle 1,A1-7 dorsal acute muscle 1,testis,male germline cell,supernumerary,somatic cell of testis,abdominal posterior fascicle & axon,motor nerve & axons.gcm,EW3 neuron & axoneg-Mz360,EW1 neuron & axoneg-Mz360,EW2 neuron & axoneg-Mz360,dMP2 neuron & axon22B" DRSC17098 IEK -2.342104419 -4.751844855 -2.071328152 -1.321560735 2.288856022 1.20174875 FBgn0036359 CG14105 - http://flybase.org/reports/FBgn0036359 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14105 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG14105 11-Aug-17 DroID_v2017_08 "Drer\stip1, Drer\ttc36" - Cele\F52H3.5 Xtro\ttc36 "Mmus\Stip1, Mmus\Ttc36" "Hsap\DNAJC3, Hsap\TTC36" viable DRSC10107 K 0.118730039 0.67355585 0.682176596 0.079869305 -0.172132357 -2.216570351 FBgn0039599 intr intrepid http://flybase.org/reports/FBgn0039599 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 sperm storage ; GO:0046693 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from sequence model "SPH202, CG12558, intr" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG12558 11-Aug-17 DroID_v2017_08 "Drer\zgc:165423, Drer\gzmk, Drer\zgc:92313, Drer\gzm3, Drer\si:dkeyp-93a5.3, Drer\cfd, Drer\zgc:163079, Drer\si:dkey-16l2.17, Drer\LOC100004427, Drer\gzma, Drer\si:ch211-165b19.8, Drer\ovch1, Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.9" - "Cele\try-6, Cele\try-1" - "Mmus\Klk9, Mmus\Klk15" "Hsap\KLK15, Hsap\TMPRSS11B, Hsap\KLK9" "viable,mating behavior defective,female limited,female semi-fertile" seminal receptacle DRSC14528 K -0.118172991 0.370531479 -0.247825348 0.463993985 0.368503487 1.968629209 FBgn0003997 hid head involution defective http://flybase.org/reports/FBgn0003997 FBgn0010852 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Diap1 BIR domain binding ; GO:1990525 | inferred from physical interaction with Diap2 inferred from physical interaction with Diap1 ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Diap1 salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype inferred from genetic interaction with rpr positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | NOT traceable author statement sex differentiation ; GO:0007548 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype programmed cell death ; GO:0012501 | inferred from mutant phenotype entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype apoptotic signaling pathway ; GO:0097190 | inferred from direct assay ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from expression pattern cell death ; GO:0008219 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype apoptotic process ; GO:0006915 | traceable author statement compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement programmed cell death ; GO:0012501 | traceable author statement positive regulation of apoptotic process ; GO:0043065 | inferred from direct assay response to red light ; GO:0010114 | inferred from mutant phenotype regulation of organ growth ; GO:0046620 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from genetic interaction with rpr cellular response to starvation ; GO:0009267 | inferred from mutant phenotype apoptotic signaling pathway ; GO:0097190 | inferred from mutant phenotype regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043281 | inferred from genetic interaction with Drice inferred from genetic interaction with Dronc inferred from genetic interaction with Decay inferred from genetic interaction with Strica inferred from genetic interaction with Dark regulation of retinal cell programmed cell death ; GO:0046668 | non-traceable author statement positive regulation of cellular response to X-ray ; GO:2000685 | inferred from mutant phenotype programmed cell death ; GO:0012501 | inferred from mutant phenotype inferred from genetic interaction with rpr positive regulation of macroautophagy ; GO:0016239 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:2001272 | inferred from direct assay apoptotic process ; GO:0006915 | non-traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype apoptotic signaling pathway ; GO:0097190 | inferred from genetic interaction with Diap1 positive regulation of cysteine-type endopeptidase activity ; GO:2001056 | inferred from direct assay intrinsic apoptotic signaling pathway in response to DNA damage ; GO:0008630 | inferred from mutant phenotype instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "hid, Hid, Hid1, HID, CG5123, l(3)05014, hid1, W, his" - CG5123 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | stage 17 midline glial cell

"visible,decreased cell death,increased cell death,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective,male,lethal - all die before end of P-stage,some die during P-stage,lethal,cell death defective,somatic clone,thermotaxis behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,viable,locomotor rhythm defective,eclosion rhythm defective,chemical resistant,circadian rhythm defective,circadian behavior defective,RU486 conditional,behavior defective,partially lethal - majority die,some die during larval stage,temperature conditional,feeding behavior defective,courtship behavior defective,lethal - all die before end of larval stage,starvation stress response defective,chemical sensitive,female limited,heat sensitive,cold sensitive,phototaxis defective,locomotor behavior defective,visual behavior defective,size defective,immune response defective,partially lethal - majority live,conditional,flightless,sleep defective,female fertile" "eye disc,eye,ommatidium,embryonic head,dorsal fold,cephalopharyngeal skeleton,dorsal bridge,male terminalia,wing disc,spermatid,arista lateral,ectopic,arista,peptidergic neuron,male genitalia,wing,ommatidial precursor cluster,dorsal closure embryo,embryonic/larval salivary gland,midline glial cell,long arista lateral,gonadal sheath proper primordium,female,follicle cell,somatic clone,nurse cell,follicle cell & nucleus | somatic clone,RU486 conditional,pigment cell,serotonergic neuron,photoreceptor cell R6,photoreceptor cell R5,photoreceptor cell,embryonic/larval trachea,dorsal,neuron | larval stage,temperature conditional,adult oenocyte,dorsal multidendritic neuron ddaC,dendriteppk.1.9,embryonic/larval carpet glial cell,heat sensitive,glial cell,rhabdomere R7,type II bouton | third instar larval stage,type I bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage,hemocyte | larval stage,tracheal metamere 2,cold sensitive,larval LN period neuron,Bolwig nerve,interommatidial bristle,Bolwig organ,pole cell | embryonic stage 16,pole cell | embryonic stage 15,pole cell | embryonic stage 14,plasmatocyte,embryonic/larval lymph gland | larval stage,gustatory receptor neuron,humeral bristle,supernumerary,ventral nerve cord commissure,embryonic hemocyte,spermathecum,chordotonal organ,embryonic brain,head,embryo,thorax,mesothoracic tergum,amnioserosa,abdominal dorsal adult muscle precursor cell,abdominal lateral adult muscle precursor cell,abdominal dorso-lateral adult muscle precursor cell" DRSC11316 E -0.540455128 -0.212070722 0.638297492 1.847782029 0.806919307 -0.696353126 FBgn0000464 Lar Leukocyte-antigen-related-like http://flybase.org/reports/FBgn0000464 FBgn0010057 protein_coding_gene transmembrane receptor protein tyrosine phosphatase activity ; GO:0005001 | inferred from sequence or structural similarity SAM domain binding ; GO:0032093 | inferred from physical interaction with ckn protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay SAM domain binding ; GO:0032093 | inferred from physical interaction with Liprin-γ "axon guidance ; GO:0007411 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Ptp99A, Ptp10D inferred from genetic interaction with Ptp10D protein dephosphorylation ; GO:0006470 | non-traceable author statement axon guidance ; GO:0007411 | traceable author statement motor neuron axon guidance ; GO:0008045 | traceable author statement embryonic development via the syncytial blastoderm ; GO:0001700 | non-traceable author statement regulation of axon extension involved in axon guidance ; GO:0048841 | inferred from mutant phenotype negative regulation of homophilic cell adhesion ; GO:1903386 | inferred from genetic interaction with bdl motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype axon target recognition ; GO:0007412 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from direct assay" focal adhesion ; GO:0005925 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay axon ; GO:0030424 | "Lar, Dlar, LAR, DLAR, dlar, DLar, CG10443, PTP38A, lar, Ptp38A" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR003598:Immunoglobulin subtype 2, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR003595:Protein-tyrosine phosphatase, catalytic, IPR003599:Immunoglobulin subtype" CG10443 11-Aug-17 DroID_v2017_08 "Drer\ptprfa, Drer\il12rb2l, Drer\ptprt, Drer\ptpreb, Drer\ptpn23a, Drer\ptprja, Drer\ptprfb, Drer\si:ch1073-391i24.1, Drer\csf3r, Drer\ptprb, Drer\ptprd, Drer\il12rb2, Drer\ptprk, Drer\il6st, Drer\ptprsa, Drer\ptprc, Drer\ptprub, Drer\ptprua, Drer\lifrb, Drer\LOC101884960, Drer\ptprdb, Drer\ptprq, Drer\ptprz1b, Drer\ptprea" "Scer\PTP1, Scer\PTP2, Scer\PTP3" "Cele\dep-1, Cele\ptp-3, Cele\F35C11.2, Cele\M05D6.3" "Xtro\ptprk, Xtro\ptpru, Xtro\ptprm, Xtro\ptpra, Xtro\ptprf, Xtro\ptpre, Xtro\ptprd, Xtro\ptprs, Xtro\ptprc" "Mmus\Ptprc, Mmus\Ptprk, Mmus\Ptpro, Mmus\Il27ra, Mmus\Ptpru, Mmus\Lifr, Mmus\Ptprm, Mmus\Ptpra, Mmus\Ptpre, Mmus\Ptprd, Mmus\Csf3r, Mmus\Il12rb2, Mmus\Il31ra, Mmus\Ptprq, Mmus\Il6st, Mmus\Osmr, Mmus\Ptprb, Mmus\Ptprz1, Mmus\Ptprf, Mmus\Ptprj, Mmus\Ptprs, Mmus\Ptprt" "Hsap\OSMR, Hsap\PTPRM, Hsap\PTPRQ, Hsap\CSF3R, Hsap\PTPRK, Hsap\PTPRC, Hsap\PTPRJ, Hsap\PTPRU, Hsap\PTPRE, Hsap\IL6ST, Hsap\IL12RB2, Hsap\PTPRB, Hsap\PTPRS, Hsap\PTPRT, Hsap\PTPRD, Hsap\PTPRF, Hsap\IL31RA, Hsap\LIFR, Hsap\PTPRA, Hsap\PTPRZ1" " embryonic stage | stage >=12 , embryonic stage " " commissure

, ventral nerve cord

, embryonic/larval trachea

, longitudinal connective

" "wild-type,optomotor response defective,somatic clone,visual behavior defective,lethal,neurophysiology defective,neuroanatomy defective,recessive,behavior defective,cell autonomous,female sterile,partially lethal - majority die,RU486 conditional,oxidative stress response defective,viable" "egg chamber,polar follicle cell,ectopic,germarium,germarium region 2b,germarium region 3,egg,follicle cell,intersegmental nerve,photoreceptor cell & growth cone | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R7 & axon | somatic clone,abdominal segmental nerve,photoreceptor cell R7,somatic clone,photoreceptor cell R7 & axon,eye disc,NMJ bouton,photoreceptor cell R7 & growth cone,photoreceptor cell R7 & growth cone | somatic clone,optic cartridge,photoreceptor cell,cell autonomous,photoreceptor cell R4,medulla,anterior fascicle & axon | ectopic,bouton,neuromuscular junction,oocyte,dorsal appendage,stage S14 oocyte,RP1 motor neuron,RP3 motor neuron,RP4 motor neuron,RP5 motor neuron,actin filament & follicle cell | somatic clone | cell non-autonomous,cell non-autonomous,longitudinal connective,intersegmental nerve branch ISNb of A1-7,supernumerary,RU486 conditional,neuromuscular junction | RU486 conditionalelav.Switch.PO,neuromuscular junctionelav.PLu,NMJ bouton | larval stage" FBgn0039140 Miro Mitochondrial Rho http://flybase.org/reports/FBgn0039140 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR020860, InterPro:IPR021181 magnesium ion binding ; GO:0000287 | inferred from direct assay calcium ion binding ; GO:0005509 | inferred from direct assay GTP binding ; GO:0005525 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q960V3-1 inferred from physical interaction with UniProtKB:Q960V3-2 inferred from physical interaction with UniProtKB:Q960V3-4 GTPase activity ; GO:0003924 | inferred from sequence model" "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR003579, InterPro:IPR020860 mitochondrion transport along microtubule ; GO:0047497 | inferred from sequence or structural similarity with UniProtKB:Q8IXI2 synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype cellular homeostasis ; GO:0019725 | inferred from sequence or structural similarity with UniProtKB:Q8IXI2 establishment of mitochondrion localization, microtubule-mediated ; GO:0034643 | inferred from mutant phenotype mitochondrial outer membrane permeabilization ; GO:0097345 | inferred from sequence or structural similarity with UniProtKB:Q8IXI2 microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype mitochondrion localization ; GO:0051646 | inferred from mutant phenotype" integral component of mitochondrial outer membrane ; GO:0031307 | inferred from sequence or structural similarity with UniProtKB:Q8IXI2 "dmiro, CG5410, DmMiro, dMiro, Miro, miro, B682, Q8IMX7-1, Q8IMX7-2, DMiro" "IPR018247:EF-Hand 1, calcium-binding site, IPR001806:Small GTPase superfamily, IPR002048:EF-hand domain, IPR013566:EF hand associated, type-1, IPR013567:EF hand associated, type-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020860:MIRO domain, IPR021181:Mitochondrial Rho GTPase, IPR011992:EF-hand domain pair" CG5410 11-Aug-17 DroID_v2017_08 "Drer\rhot2, Drer\rhot1a, Drer\rhot1b, Drer\si:ch73-40i7.2" "Scer\GEM1, Scer\RHO4" Cele\miro-1 "Xtro\rhot1, Xtro\rhot2" "Mmus\Rhot1, Mmus\Rhot2" "Hsap\RHOT2, Hsap\RHOT1" "phototaxis defective,somatic clone,partially lethal - majority die,recessive,locomotor behavior defective,body size defective,neurophysiology defective,some die during pupal stage,neuroanatomy defective" "mitochondrion & motor neuron | larval stageRapGAP1-OK6,mitochondrion & neuron | larval stage,mitochondrion & somatic muscle | larval stage,bouton & neuromuscular junction | larval stage,somatic muscle,microtubule & bouton,mitochondrion,mitochondrion & motor neuron | larval stage,mitochondrion & neuromuscular junction | supernumerary | larval stage,neuron,midline primordium,dendrite,dorsal multidendritic neuron ddaE,mitochondrionrepo.PL, repo,embryonic/larval glial cell,photoreceptor cell,mitochondrionGMR.PF,lamina,adult brain,mitochondrionelav.PU" FBgn0003964 usp ultraspiracle http://flybase.org/reports/FBgn0003964 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000003, InterPro:IPR001628, InterPro:IPR013088 hormone binding ; GO:0042562 | inferred from direct assay juvenile hormone binding ; GO:0005500 | traceable author statement transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay ecdysteroid hormone receptor activity ; GO:0004884 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with EcR ecdysone binding ; GO:0035100 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Utx RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ; GO:0004879 | non-traceable author statement DNA binding ; GO:0003677 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with EcR protein binding ; GO:0005515 | inferred from physical interaction with rig protein binding ; GO:0005515 | inferred from physical interaction with egg protein heterodimerization activity ; GO:0046982 | inferred from direct assay ecdysteroid hormone receptor activity ; GO:0004884 | contributes_to inferred from physical interaction with EcR lipid binding ; GO:0008289 | inferred from direct assay" "steroid hormone mediated signaling pathway ; GO:0043401 | inferred from electronic annotation with InterPro:IPR000536 neuron development ; GO:0048666 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype cellular response to ecdysone ; GO:0071390 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement dendrite morphogenesis ; GO:0048813 | non-traceable author statement regulation of development, heterochronic ; GO:0040034 | traceable author statement pupariation ; GO:0035073 | inferred from mutant phenotype regulation of organ growth ; GO:0046620 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype response to ecdysone ; GO:0035075 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of cell differentiation ; GO:0045596 | traceable author statement" polytene chromosome ; GO:0005700 | non-traceable author statement dendrite ; GO:0030425 | inferred from mutant phenotype activator ecdysone receptor complex ; GO:0008232 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay ecdysone receptor holocomplex ; GO:0008230 | traceable author statement ecdysone receptor holocomplex ; GO:0008230 | inferred from physical interaction with EcR "DmUSP, usp, USP, Usp, CF1, CG4380, dUSP, EG:22E5.1, dmUSP, NR2B4, DmUsp, CF1/Usp, CF1/USP, 2C, XR2C, Cf1, l(1)usp, l(1)2Cf, cf1" "IPR013088:Zinc finger, NHR/GATA-type, IPR000536:Nuclear hormone receptor, ligand-binding domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001723:Nuclear hormone receptor, IPR000003:Retinoid X receptor/HNF4" CG4380 11-Aug-17 DroID_v2017_08 "Drer\raraa, Drer\nr2f5, Drer\esr2a, Drer\pparg, Drer\rargb, Drer\esrra, Drer\nr2f1a, Drer\nr1i2, Drer\vdrb, Drer\nr2e3, Drer\nr1h4, Drer\rxrba, Drer\ppardb, Drer\nr6a1b, Drer\esrrd, Drer\pparab, Drer\nr2c2, Drer\nr2c1, Drer\nr3c1, Drer\pparda, Drer\nr2f2, Drer\nr2f1b, Drer\rxrab, Drer\nr0b2a, Drer\nr1h5, Drer\rxrbb, Drer\nr2e1, Drer\ar, Drer\nr0b2b, Drer\thrab, Drer\esr2b, Drer\nr2f6b, Drer\vdra, Drer\rxrga, Drer\rarab, Drer\rxraa, Drer\pgr, Drer\pparaa, Drer\esrrga, Drer\nr5a1a, Drer\rxrgb, Drer\nr0b1, Drer\esr1, Drer\nr2f6a" - "Cele\sex-1, Cele\nhr-6, Cele\nhr-14, Cele\nhr-133, Cele\nhr-1, Cele\unc-55, Cele\nhr-49" "Xtro\esr2, Xtro\pgr, Xtro\rara, Xtro\esr1, Xtro\pparg, Xtro\esrrg, Xtro\rarg, Xtro\nr0b2, Xtro\nr1i2, Xtro\esrrb, Xtro\rxra, Xtro\nr2f6, Xtro\ar, Xtro\thrb, Xtro\rxrg, Xtro\rarb, Xtro\nr3c1, Xtro\ppara, Xtro\nr2f5, Xtro\nr1h2, Xtro\esrra, Xtro\vdr, Xtro\nr2e1, Xtro\nr2f1, Xtro\nr2f2, Xtro\ppard, Xtro\nr0b1, Xtro\nr2e3, Xtro\nr2c1, Xtro\rxrb, Xtro\nr3c2, Xtro\nr6a1, Xtro\esrrgr, Xtro\nr1h5, Xtro\nr2c2" "Mmus\Rxra, Mmus\Rarg, Mmus\Nr2f6, Mmus\Esrra, Mmus\Nr1i2, Mmus\Rxrg, Mmus\Esr2, Mmus\Ppara, Mmus\Nr1h4, Mmus\Nr6a1, Mmus\Ar, Mmus\Rara, Mmus\Nr0b2, Mmus\Nr1h5, Mmus\Nr3c1, Mmus\Esrrb, Mmus\Nr1i3, Mmus\Pparg, Mmus\Nr2c1, Mmus\Nr2c2, Mmus\Rxrb, Mmus\Nr1h2, Mmus\Nr3c2, Mmus\Vdr, Mmus\Nr2e1, Mmus\Nr2f1, Mmus\Nr1h3, Mmus\Esrrg, Mmus\Thrb, Mmus\Nr2f2, Mmus\Pgr, Mmus\Thra, Mmus\Rarb, Mmus\Esr1, Mmus\Ppard, Mmus\Nr0b1, Mmus\Nr2e3" "Hsap\PPARD, Hsap\NR1H4, Hsap\ESR2, Hsap\NR2C2, Hsap\ESRRG, Hsap\NR0B2, Hsap\NR1H2, Hsap\PGR, Hsap\RXRB, Hsap\RARA, Hsap\NR3C1, Hsap\THRA, Hsap\RXRG, Hsap\PPARA, Hsap\NR0B1, Hsap\NR1I3, Hsap\THRB, Hsap\RARB, Hsap\NR1H3, Hsap\AR, Hsap\PPARG, Hsap\NR2C1, Hsap\NR2E1, Hsap\NR1I2, Hsap\ESRRA, Hsap\NR6A1, Hsap\NR2F6, Hsap\ESRRB, Hsap\NR2F1, Hsap\RXRA, Hsap\RARG, Hsap\ESR1, Hsap\VDR, Hsap\NR3C2, Hsap\NR2F2" " adult stage && oogenesis stage , embryonic stage | stage 12 , adult stage && oogenesis stage | stage >=S8 , embryonic stage | early , oogenesis stage && adult stage | female , embryonic stage -- adult stage " " follicle cell

, ventral nerve cord

, oocyte

, nurse cell

, embryonic/larval midgut

,

ubiquitous , ovary

" " larval stage | late third instar larval stage , embryonic stage--pupal stage , larval stage | third instar , adult stage && oogenesis stage " " larval central nervous system

, embryonic/larval fat body

, dorsal mesothoracic disc

, antennal disc

, eye disc

, ring gland

, ventral thoracic disc

, nurse cell

, follicle cell

, embryonic/larval salivary gland

" "neuroanatomy defective,hypoactive,touch sensitivity defective,wild-type,lethal,recessive,germline clone,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,maternal effect,lethal - all die during first instar larval stage,lethal - all die during P-stage,partially,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,circadian rhythm defective" "mushroom body gamma-lobe | adult stage,adult mushroom body,embryonic/larval anterior spiracle,imaginal disc,embryonic/larval midgut | embryonic stage,midgut imaginal island,embryonic/larval salivary gland | embryonic stage,egg,germline clone,maternal effect,dorsal appendage,terminal filament,olfactory neuron & axon,olfactory neuron & dendrite,antennal lobe & axon,adult mushroom body & axon,ommatidial precursor cluster,somatic clone,morphogenetic furrow,dorsal mesothoracic disc & neuron | somatic clone,embryo,posterior,dendritic arborizing neuron,gamma-lobe & neuron | somatic clone,rhabdomere,retina,cell non-autonomous,mushroom body gamma-lobe,adult antennal lobe projection neuron,persistent antennal lobe projection neuron,egg chamber,embryonic/first instar larval cuticle,puparium,anterior pupal spiracle,border follicle cell,triple row,ectopic,precursor,ommatidium,female germline cell,supernumerary,heat sensitive,lobe system of adult mushroom body,mushroom body beta-lobe,dendrite109(2)80,dorsal multidendritic neuron ddaC,midgut constriction,embryonic/larval tracheal system" FBgn0266756 btsz bitesize http://flybase.org/reports/FBgn0266756 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from electronic annotation with InterPro:IPR010911 calcium-dependent phospholipid binding ; GO:0005544 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR010911 lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype regulation of calcium ion-dependent exocytosis ; GO:0017158 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype apical junction assembly ; GO:0043297 | inferred from mutant phenotype vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype establishment of planar polarity of embryonic epithelium ; GO:0042249 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from biological aspect of ancestor with PANTHER:PTN000001285" plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 apical plasma membrane ; GO:0016324 | inferred from direct assay "CG44012, btsz, CG7343, Btsz, CG17304, CG33555, CG14858, CG31306, l(3)10418, BcDNA:GH06647, CG18280, Granulophilin" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR010911:Rab-binding domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR000008:C2 domain, IPR001565:Synaptotagmin" CG44012 11-Aug-17 DroID_v2017_08 "Drer\sytl3, Drer\syt17, Drer\syt5b, Drer\sytl4, Drer\sytl2a, Drer\sytl5, Drer\syt3, Drer\syt9a, Drer\syt4, Drer\syt5a, Drer\syt2a, Drer\si:ch211-266g18.6, Drer\syt11b, Drer\syt1b, Drer\sytl2b, Drer\sytl1, Drer\syt10, Drer\syt11a, Drer\zgc:162595, Drer\pla2g4f.1, Drer\pla2g4f.2, Drer\syt9b, Drer\LOC568754, Drer\LOC100332608" - - "Xtro\sytl2, Xtro\jmjd7-pla2g4b, Xtro\sytl1, Xtro\sytl4, Xtro\sytl5, Xtro\sytl3, Xtro\pla2g4f, Xtro\syt3, Xtro\syt4" "Mmus\Pla2g4e, Mmus\Sytl1, Mmus\Syt9, Mmus\C2cd4d, Mmus\Tc2n, Mmus\Syt5, Mmus\Syt10, Mmus\Sytl2, Mmus\C2cd4b, Mmus\Syt4, Mmus\Sytl5, Mmus\Sytl4, Mmus\Syt15, Mmus\Syt8, Mmus\Pla2g4f, Mmus\Sytl3, Mmus\Syt17, Mmus\C2cd4c, Mmus\Syt11, Mmus\Pla2g4b, Mmus\Syt2, Mmus\Pla2g4d, Mmus\C2cd4a" "Hsap\SYT4, Hsap\PLA2G4E, Hsap\SYT16, Hsap\SYT8, Hsap\SYT7, Hsap\TC2N, Hsap\SYT11, Hsap\SYTL2, Hsap\SYTL1, Hsap\C2CD4D, Hsap\SYT2, Hsap\SYTL3, Hsap\SYTL5, Hsap\PLA2G4D, Hsap\SYT5, Hsap\SYT10, Hsap\SYTL4, Hsap\SYT15, Hsap\PLA2G4F, Hsap\C2CD4A, Hsap\SYT17, Hsap\C2CD4C, Hsap\SYT9, Hsap\C2CD4B, Hsap\PLA2G4B" DRSC15320 IK 1.532210447 -0.68566855 0.390924927 0.177955209 2.875074787 -0.23369725 FBgn0000017 Abl Abl tyrosine kinase http://flybase.org/reports/FBgn0000017 "FBgn0024512, FBgn0036649" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR015015, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Abi protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8T4F7 protein tyrosine kinase activity ; GO:0004713 | inferred from sequence alignment with UniProtKB:P00519 inferred from sequence or structural similarity inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with spri protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from mutant phenotype non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from direct assay receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357" "innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 regulation of protein stability ; GO:0031647 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with robo1 regulation of actin polymerization or depolymerization ; GO:0008064 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype regulation of protein localization ; GO:0032880 | inferred from direct assay axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | non-traceable author statement peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction withFB:FBgn0262742 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype epithelial cell morphogenesis ; GO:0003382 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype planar cell polarity pathway involved in axis elongation ; GO:0003402 | inferred from mutant phenotype ventral furrow formation ; GO:0007370 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from genetic interaction with Nrt regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype negative regulation of neuron projection development ; GO:0010977 | inferred from mutant phenotype positive regulation of lamellipodium assembly ; GO:0010592 | inferred from mutant phenotype dorsal closure ; GO:0007391 | non-traceable author statement positive regulation of protein export from nucleus ; GO:0046827 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype inferred from genetic interaction with eya ventral cord development ; GO:0007419 | inferred from genetic interaction with Dscam1 chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from direct assay branchiomotor neuron axon guidance ; GO:0021785 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from genetic interaction with Nrt neuron migration ; GO:0001764 | inferred from mutant phenotype transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 regulation of cell shape ; GO:0008360 | non-traceable author statement regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein phosphorylation ; GO:0006468 | non-traceable author statement compound eye development ; GO:0048749 | inferred from genetic interaction with eya" apical cortex ; GO:0045179 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay extrinsic component of plasma membrane ; GO:0019897 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 axon ; GO:0030424 | inferred from direct assay cell-cell junction ; GO:0005911 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay adherens junction ; GO:0005912 | traceable author statement muscle tendon junction ; GO:0005927 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay "D-abl, abl, Ableson, AblK, CG4032, DROTKABL3, ABL, Ddash/abl, DAbl, c-abl, 4674, Dash, Am ABL, Dabl, l(3)04674, cAbl, D-ash, l(3)c-abl, l(3)73Ba, abl1, Dsrc7, C-abl, Abl1, Abl, dAbl, D-Abl" "IPR000719:Protein kinase domain, IPR000980:SH2 domain, IPR001452:SH3 domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR015015:F-actin binding, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG4032 11-Aug-17 DroID_v2017_08 "Drer\abl1, Drer\tec, Drer\btk, Drer\zgc:194282, Drer\lyn, Drer\frk, Drer\itk, Drer\yes1, Drer\ttbk1b, Drer\src, Drer\lck, Drer\hck, Drer\fyna, Drer\abl2" - "Cele\src-1, Cele\src-2, Cele\abl-1, Cele\Y47G6A.5" "Xtro\abl2, Xtro\fyn, Xtro\lck, Xtro\btk, Xtro\lyn, Xtro\tec, Xtro\yes1, Xtro\abl1, Xtro\src, Xtro\fgr" "Mmus\Frk, Mmus\Abl2, Mmus\Btk, Mmus\Yes1, Mmus\Blk, Mmus\Fgr, Mmus\Abl1, Mmus\Itk, Mmus\Bmx, Mmus\Lck, Mmus\Tec, Mmus\Fyn, Mmus\Lyn, Mmus\Src, Mmus\Txk, Mmus\Srms" "Hsap\TXK, Hsap\BTK, Hsap\LYN, Hsap\ITK, Hsap\ABL2, Hsap\FYN, Hsap\TEC, Hsap\BLK, Hsap\BMX, Hsap\ABL1, Hsap\FRK, Hsap\SRMS, Hsap\FGR, Hsap\SRC, Hsap\HCK, Hsap\LCK" " prepupal stage--pupal stage , oogenesis stage && adult stage | female , embryonic stage , adult stage | female , adult stage && oogenesis stage " " ovary

, oocyte

" " embryonic stage , embryonic stage | late , embryonic stage | early " " embryonic central nervous system

, epithelial cell

, adepithelial cell

, epithelial cell | apical

, neuron

, imaginal disc

" "lethal,neuroanatomy defective,viable,fertile,recessive,wild-type,partially lethal - majority die,somatic clone,cell migration defective,germline clone,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,reduced,visible,partially lethal - majority live,mitotic cell cycle defective,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage,neurophysiology defective,size defective,heat sensitive,cell shape defective" "synaptic vesicle & NMJ bouton,longitudinal connective,presumptive embryonic/larval central nervous system,commissure,embryonic leading edge cell,dorsal closure embryo,extended germ band embryo,amnioserosa,antennal lobe glomerulus,antennal commissure,intersegmental nerve,NMJ bouton,supernumerary,longitudinal connective | embryonic stage,ommatidium,longitudinal connective | embryonic stage 16,embryonic/larval neuron,central nervous system,ventral nerve cord,lamina,somatic clone,RP2 motor neuron,EW neuron,germline clone,maternal effect,intersegmental nerve branch ISNb of A1-7,segmental nerve branch SNa of A1-7,eye,follicle cell & actin filament | somatic clone,follicle cell,actin cytoskeleton | embryonic stage | maternal effect,interommatidial bristle,eye photoreceptor cell,embryonic/first instar larval cuticle,dorsal,ventral furrow,non-rescuable maternal effect,spindle | cleavage stage | maternal effect,anterior commissure,posterior commissure,egg,actin filament & egg chamber | germ-line clone,ventral nerve cord commissure,embryonic/larval neuromuscular junction,midline crossing tract,heat sensitive,retina,ventral adult lateral neuron & axonP2.4.Pdf" FBgn0000580 eor extra organs http://flybase.org/reports/FBgn0000580 FBgn0017382 gene molecular_function ; GO:0003674 | no biological data available gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "lA7, A7, l(1)E-54, E54, 17, lN-30, 12, N-30, l(1)20Af, l(1)20Aa, l(1)17-252, eor, eo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,germline clone,rescuable maternal effect,visible,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "eye,leg,antenna,arista,embryo,germline clone,embryonic/first instar larval cuticle,wing" FBgn0050324 CG30324 - http://flybase.org/reports/FBgn0050324 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7750, CG30324" - CG30324 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0028987 Spn28F Serpin 28F http://flybase.org/reports/FBgn0028987 protein_coding_gene hormone binding ; GO:0042562 | inferred from sequence or structural similarity serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from sequence or structural similarity serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of proteolysis ; GO:0045861 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "CG8137, sp2, Sp2, Spn2, Spn28F, spn2" "IPR000215:Serpin family, IPR023796:Serpin domain" CG8137 11-Aug-17 DroID_v2017_08 "Drer\serpinb1l1, Drer\serpinc1, Drer\serpinh1a, Drer\serpine2, Drer\serpinb14, Drer\zgc:173729, Drer\serpine3, Drer\serpinh2, Drer\serpinb1l3, Drer\serpine1, Drer\serpinb1, Drer\serpina1l, Drer\serpini1, Drer\serpinb1l4, Drer\serpinh1b, Drer\serpinb1l2, Drer\si:ch211-186e20.7, Drer\serpina7, Drer\si:ch1073-416d2.3, Drer\zgc:174259, Drer\serpind1, Drer\serpina10a" - "Cele\srp-3, Cele\srp-8, Cele\srp-2, Cele\srp-1, Cele\srp-7, Cele\srp-6" "Xtro\serpina3m, Xtro\serpinh1, Xtro\serpina3, Xtro\serpini1, Xtro\serpine1, Xtro\serpinb1, Xtro\serpind1, Xtro\serpinb6, Xtro\serpinb11, Xtro\serpina1, Xtro\serpinb4, Xtro\serpinb5, Xtro\serpine2, Xtro\serpini2, Xtro\serpina10, Xtro\serpina3k, Xtro\serpinc1" "Mmus\Serpina6, Mmus\Serpinb13, Mmus\Serpinb9f, Mmus\Serpinb3a, Mmus\Gm11397, Mmus\Serpina5, Mmus\Serpine3, Mmus\Serpind1, Mmus\Serpinb2, Mmus\Serpina3c, Mmus\Serpina3i, Mmus\Serpinb6d, Mmus\Serpinb6e, Mmus\Serpinb9e, Mmus\Serpina3f, Mmus\Serpinb6a, Mmus\Serpina1d, Mmus\Serpina3k, Mmus\Serpinb7, Mmus\Serpinb9, Mmus\Serpinb11, Mmus\Serpinb5, Mmus\Serpina12, Mmus\Serpina1c, Mmus\Serpinb6c, Mmus\Serpina3g, Mmus\Serpinc1, Mmus\Serpine1, Mmus\Serpina1a, Mmus\Serpina1f, Mmus\Serpina9, Mmus\Serpinb1b, Mmus\Serpina1e, Mmus\Serpinb1c, Mmus\Serpinb3c, Mmus\Serpina10, Mmus\Serpinb8, Mmus\Serpina3j, Mmus\Serpinb3b, Mmus\Serpina16, Mmus\Serpinb6b, Mmus\Serpini1, Mmus\Serpinb3d, Mmus\Serpinb9d, Mmus\Serpinb9c, Mmus\Serpinb10, Mmus\Serpinb12, Mmus\Serpina3n, Mmus\Serpinb1a, Mmus\Serpini2, Mmus\Serpina3a, Mmus\Serpina11, Mmus\Serpina7, Mmus\Serping1, Mmus\Serpinh1, Mmus\Serpinb9g, Mmus\Serpine2, Mmus\Serpinb9b" "Hsap\SERPINE3, Hsap\SERPINA11, Hsap\SERPINB12, Hsap\SERPINB11, Hsap\SERPINA2, Hsap\SERPINA7, Hsap\SERPINA6, Hsap\SERPINI2, Hsap\SERPINB1, Hsap\SERPINB7, Hsap\SERPINA5, Hsap\SERPINB3, Hsap\SERPINB10, Hsap\SERPINB9, Hsap\SERPINB13, Hsap\SERPINB4, Hsap\SERPINB6, Hsap\SERPINA3, Hsap\SERPINA1, Hsap\SERPINC1, Hsap\SERPINB5, Hsap\SERPING1, Hsap\SERPINA4, Hsap\SERPINB2, Hsap\SERPINE1, Hsap\SERPINA9, Hsap\SERPINA10, Hsap\SERPINE2, Hsap\SERPINA12, Hsap\SERPIND1, Hsap\SERPINH1, Hsap\SERPINI1, Hsap\SERPINB8, Hsap\HMSD" lethal FBgn0266260 CR44955 - http://flybase.org/reports/FBgn0266260 non_protein_coding_gene - - - "CR44955, lincRNA.737" - CR44955 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0000135 arth arthritic http://flybase.org/reports/FBgn0000135 - gene - - - "l(1)1Ah, arth" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,uncoordinated" "leg,tarsal segment,unguis" FBgn0038043 CG17202 - http://flybase.org/reports/FBgn0038043 protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from electronic annotation with InterPro:IPR026060 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR026060" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q99417 "BcDNA:RH21090, CG17202" "IPR003117:cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, IPR026060:Associate of Myc 1" CG17202 11-Aug-17 DroID_v2017_08 Drer\mycbp - - Xtro\mycbp Mmus\Mycbp Hsap\MYCBP FBgn0001108 DCTN1-p150 "Dynactin 1, p150 subunit" http://flybase.org/reports/FBgn0001108 - protein_coding_gene dynein complex binding ; GO:0070840 | inferred from direct assay dynein complex binding ; GO:0070840 | inferred from physical interaction with Dhc64C dynein intermediate chain binding ; GO:0045505 | inferred from physical interaction with sw dynein complex binding ; GO:0070840 | traceable author statement mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from genetic interaction with dop rhabdomere development ; GO:0042052 | inferred from mutant phenotype centrosome localization ; GO:0051642 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype mRNA transport ; GO:0051028 | inferred from mutant phenotype protein localization to kinetochore ; GO:0034501 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype kinetochore organization ; GO:0051383 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype mitochondrion transport along microtubule ; GO:0047497 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from genetic interaction with Strip inferred from genetic interaction with spri mitotic spindle midzone assembly ; GO:0051256 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype retrograde axonal transport ; GO:0008090 | inferred from mutant phenotype eye photoreceptor cell differentiation ; GO:0001754 | inferred from mutant phenotype cell fate determination ; GO:0001709 | inferred from mutant phenotype establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from direct assay microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype centrosome separation ; GO:0051299 | inferred from mutant phenotype retrograde synaptic vesicle transport ; GO:0048491 | inferred from direct assay dynactin complex ; GO:0005869 | inferred from electronic annotation with InterPro:IPR027663 dynactin complex ; GO:0005869 | traceable author statement microtubule plus-end ; GO:0035371 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay spindle microtubule ; GO:0005876 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay spindle pole centrosome ; GO:0031616 | inferred from direct assay aster ; GO:0005818 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay dynactin complex ; GO:0005869 | inferred from sequence or structural similarity "Glued, p150/glued, p150[Glued], p150, CG9206, Glu, p150/Glued, t1, Gl, P150[Glued], p150[glued], P150, DYNA_DROME, FCP-D, DCTN1, DCTN1-p150, P150A, gl" "IPR000938:CAP Gly-rich domain, IPR027663:Dynactin subunit 1, IPR022157:Dynein associated protein" CG9206 11-Aug-17 DroID_v2017_08 "Drer\dctn1a, Drer\clip1a, Drer\clip2, Drer\clip3, Drer\dctn1b" "Scer\NIP100, Scer\BIK1, Scer\ALF1" "Cele\dnc-1, Cele\clip-1, Cele\F59A6.5" "Xtro\clip3, Xtro\dctn1" "Mmus\Clip3, Mmus\Clip1, Mmus\Dctn1, Mmus\Clip2" "Hsap\DCTN1, Hsap\SLC4A5, Hsap\CLIP2, Hsap\CLIP3, Hsap\CLIP1" " adult stage && oogenesis stage , embryonic stage&&larval stage&&pupal stage , larval stage | late , egg stage | unfertilized egg , spermatogenesis && adult stage , embryonic stage , adult stage , embryonic stage&&pupal stage " " ovary

, unfertilized egg

, testis

, adult head

" " adult stage && oogenesis stage | stage S9 , oogenesis stage | early , adult stage && oogenesis stage " " oocyte | posterior

, germarium region 2b && oocyte

" "lethal - all die before end of pupal stage,recessive,some die during pupal stage,neuroanatomy defective,neurophysiology defective,viable,sterile,locomotor behavior defective,flightless,short lived,cell shape defective,somatic clone,visible,cell polarity defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,mitotic cell cycle defective,lethal,dominant,eye color defective,fertile,wild-type,heat sensitive,paralytic,female sterile,lethal - all die before end of second instar larval stage,some die during second instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,male fertile,lethal - all die before end of larval stage,some die during larval stage,partially,uncoordinated,conditional,proboscis extension reflex defective,progressive,immune response defective" "NMJ bouton,follicle cell,somatic clone,eye,mitochondrionD42,spindleC587,cyst progenitor cell,ommatidium,spindle pole centrosome,spindle,cone cell,nervous system & thorax & pupa,sensory neuron,motor neuron,lipid particle | maternal effect,pigment cell,prothoracic femoral chordotonal organ & axon,mesothoracic femoral chordotonal organ & axon,metathoracic femoral chordotonal organ & axon,sensillum trichodeum & leg & axon,photoreceptor cell,synapse,interommatidial bristle,macrochaeta,eye photoreceptor cell & nucleus,eye photoreceptor cell & microtubule,eye photoreceptor cell,rhabdomere,primary pigment cell,secondary pigment cell,tertiary pigment cell,giant fiber neuron,giant fibers & synapse,mitochondrion,Golgi apparatus,optic lobe,wing,photoreceptor cell R1,photoreceptor cell R6,posterior fascicle & axon,cuticle,synapse & neuromuscular junction,postsynaptic membrane,bouton,giant fibers & nerve terminal,giant fibers & nerve terminalc17,giant fibers & synapsec17,eye disc,morphogenetic furrow,eye photoreceptor cell & nucleusGlass38-1,larval Bolwig's organ & nucleuselav.PLu,embryonic/larval neuron,photoreceptor cell R7,segmental nerve,conditional,synapseRapGAP1-OK6,CSD interneuron,type Ib terminal bouton | third instar larval stageD42,external sensory organ precursor cell I,centrosomeneur-P72,adult neuromuscular junction,proboscis muscle,border follicle cell,ganglion mother cell" DRSC11175 I 2.114087164 0.32034091 -0.62696453 -0.006911854 0.20996873 0.714014678 FBgn0051549 CG31549 - http://flybase.org/reports/FBgn0051549 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "CG11005, CG31549" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG31549 11-Aug-17 DroID_v2017_08 "Drer\elovl2, Drer\hsd17b14, Drer\elovl1b, Drer\elovl7b, Drer\elovl8b, Drer\dhrs1, Drer\cbr4, Drer\elovl1a, Drer\bdh2, Drer\hsdl2, Drer\zgc:101858, Drer\hsd17b8, Drer\elovl7a, Drer\dhrs7, Drer\zgc:113054, Drer\pecr, Drer\elovl4a, Drer\elovl4b, Drer\decr2, Drer\decr1, Drer\elovl8a, Drer\elovl5" "Scer\IRC24, Scer\YIR035C, Scer\OAR1, Scer\SPS19" "Cele\ZK829.1, Cele\F28H7.2, Cele\F25D1.5, Cele\F26D2.15, Cele\dhs-25, Cele\dhs-11, Cele\Y47G6A.21, Cele\Y47G6A.22, Cele\C33E10.10, Cele\dhs-14, Cele\C06E4.3" "Xtro\elovl7, Xtro\hsd17b8, Xtro\elovl2, Xtro\elovl5, Xtro\decr1, Xtro\dhrs4, Xtro\decr2, Xtro\pecr, Xtro\MGC79752, Xtro\MGC147226, Xtro\elovl1, Xtro\hsd17b14, Xtro\dhrs7, Xtro\hsdl2, Xtro\cbr4" "Mmus\Elovl7, Mmus\Elovl2, Mmus\Decr1, Mmus\Bdh2, Mmus\Cbr4, Mmus\Hsdl2, Mmus\Elovl4, Mmus\Dhrs2, Mmus\Pecr, Mmus\Elovl5, Mmus\Dhrs1, Mmus\H2-Ke6, Mmus\Dhrs7, Mmus\Hsd17b14, Mmus\Dhrs4, Mmus\Decr2" "Hsap\CBR4, Hsap\DHRS2, Hsap\HSD17B8, Hsap\ELOVL7, Hsap\DHRS4, Hsap\HSDL2, Hsap\ELOVL4, Hsap\DECR2, Hsap\ELOVL5, Hsap\DHRS7, Hsap\BDH2, Hsap\HSD17B14, Hsap\ELOVL1, Hsap\ELOVL2, Hsap\PECR, Hsap\DHRS1, Hsap\DECR1, Hsap\DHRS4L2" FBgn0033638 CG9005 - http://flybase.org/reports/FBgn0033638 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "BcDNA:GH05710, CG9005" "IPR025261:Domain of unknown function DUF4210, IPR033473:Protein FAM214/SPAC3H8.04, C-terminal" CG9005 11-Aug-17 DroID_v2017_08 "Drer\fam214b, Drer\fam214a" - Cele\F23D12.10 Xtro\fam214a "Mmus\Fam214b, Mmus\Fam214a" "Hsap\FAM214A, Hsap\FAM214B" "viable,body color defective" mesothoracic tergum FBgn0001237 hup hold up http://flybase.org/reports/FBgn0001237 - gene molecular_function ; GO:0003674 | no biological data available cell fate commitment ; GO:0045165 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype morphogenesis of follicular epithelium ; GO:0016333 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from genetic interaction with Egfr oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available hup - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,male sterile" "egg,egg chamber,egg chamber & nucleus,dorsal appendage,wing,oocyte,micropyle" FBgn0086208 su(comp)3R-1 - http://flybase.org/reports/FBgn0086208 gene - regulation of growth ; GO:0040008 | inferred from mutant phenotype inferred from genetic interaction with RpL36 - su(comp)3R-1 - - 11-Aug-17 DroID_v2017_08 - - - - - - "hyperplasia,recessive,somatic clone,visible" "wing disc,somatic clone,eye,wing" FBgn0264377 CG43829 - http://flybase.org/reports/FBgn0264377 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43829 - CG43829 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040872 CG12694 - http://flybase.org/reports/FBgn0040872 protein_coding_gene - - - CG12694 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0013343 Syx1A Syntaxin 1A http://flybase.org/reports/FBgn0013343 "FBgn0010900, FBgn0023459, FBgn0039148, FBgn0042210, FBgn0066005" protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with Syt1, Syt4 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNAP receptor activity ; GO:0005484 | inferred from direct assay SNARE binding ; GO:0000149 | inferred from physical interaction with Snap25, nSyb SNAP receptor activity ; GO:0005484 | non-traceable author statement" regulation of exocytosis ; GO:0017157 | inferred from electronic annotation with InterPro:IPR028669 regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype synaptic vesicle fusion to presynaptic active zone membrane ; GO:0031629 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 vesicle-mediated transport ; GO:0016192 | non-traceable author statement synaptic vesicle fusion to presynaptic active zone membrane ; GO:0031629 | inferred from direct assay neuromuscular synaptic transmission ; GO:0007274 | inferred from expression pattern cellularization ; GO:0007349 | non-traceable author statement vesicle fusion ; GO:0006906 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype vesicle docking ; GO:0048278 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity cellularization ; GO:0007349 | traceable author statement haltere development ; GO:0007482 | inferred from genetic interaction with Ubx plasma membrane ; GO:0005886 | inferred from direct assay SNARE complex ; GO:0031201 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 synaptic vesicle ; GO:0008021 | inferred from direct assay plasma membrane ; GO:0005886 | non-traceable author statement terminal bouton ; GO:0043195 | inferred from direct assay "Syx1a, syx-1A, syx, Syx, syx1A, DmSyx1A, CG10716, CT30033, CG5448, syx1, Dm Syx1, SYX1A, synt, syx-1, syt-1A, anon-EST:Gibbs4, l(3)06737, Syt1A, CG18615, CG31136, anon-WO02059370.54, Syx1A, Syx1, CG31136/CG33100, SyxA, Syx-1A, SYX, SYX 1A, dsyn-1A, dSyx1, Stx1a" "IPR000727:Target SNARE coiled-coil homology domain, IPR006011:Syntaxin, N-terminal domain, IPR006012:Syntaxin/epimorphin, conserved site, IPR010989:SNARE, IPR028669:Syntaxin 1" CG31136 11-Aug-17 DroID_v2017_08 "Drer\stx3a, Drer\stx11b.1, Drer\stx2b, Drer\stx19, Drer\stx1a, Drer\zgc:165520, Drer\stx1b, Drer\stx2a, Drer\stx11a, Drer\stx4, Drer\stx11b.2" "Scer\SSO2, Scer\SSO1" "Cele\syx-2, Cele\unc-64" "Xtro\LOC100494194, Xtro\stx19, Xtro\stx11, Xtro\stx3, Xtro\stx1a, Xtro\stx2" "Mmus\Stx11, Mmus\Stx1b, Mmus\Stx1a, Mmus\Stx4a, Mmus\Stx2, Mmus\Stx3, Mmus\Stx19" "Hsap\STX19, Hsap\STX4, Hsap\STX2, Hsap\STX1B, Hsap\STX1A, Hsap\STX3, Hsap\STX11" " embryonic stage | early , embryonic stage | stage 9 , embryonic stage , embryonic stage -- adult stage " " organism | 0% egg length

, ectoderm

, central nervous system

, embryonic peripheral nervous system

, posterior midgut proper primordium

,

ubiquitous , anterior midgut proper primordium

, neuroblast

, embryonic/larval garland cell

, embryonic neuron

, amnioproctodeal invagination

" " embryonic stage | stage 15-17 , embryonic stage , adult stage , embryonic stage | early , embryonic stage | stage 9 , larval stage , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-8 " " ectoderm

, neuron

, neuropil

, commissure

, pole bud

, lamina

, embryonic peripheral nervous system

, neuromuscular junction

, central nervous system

, synapse

, longitudinal connective

, germline cyst

, nurse cell

,

ubiquitous , germarium region 3

, medulla

, posterior embryonic/larval midgut

, bouton

, germarium region 2b

, germarium region 2a

, cell body

, anterior embryonic/larval midgut

, adult brain

, ventral neurogenic region

, embryonic/larval garland cell

, mesoderm

" "wild-type,neurophysiology defective,heat sensitive,lethal,recessive,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,partially,viable,hypoactive,paralytic,semidominant,visual behavior defective,neuroanatomy defective,uncoordinated,dominant,visible,somatic clone,cytokinesis defective,maternal effect" "neuromuscular junction,eye,ommatidium,somatic muscle,embryonic/first instar larval cuticle,wing,neuromuscular junction | embryonic stage,synapse,denticle,neuromuscular junction | larval stage,embryonic epidermis,embryonic/larval muscle system,synapse | embryonic stage, with Syx1A‘î229,retina,optic cartridge & synaptic vesicle,eye photoreceptor cell,somatic clone,oocyte,germline clone,longitudinal connective,intersegmental nerve,segmental nerve,mitotic telophase,mitotic telophase & spindle,actomyosin contractile ring,synapse | embryonic stage, with Syx1AA243V.V247A,mouth hooks,denticle belt,embryonic foregut,embryonic/larval midgut primordium,embryonic hindgut,ventral nerve cord,maternal effect,embryonic/larval midgut,egg,embryo,cytoskeleton | embryonic stage | germline clone,nucleus | embryonic stage | germline clone,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0002940 ninaE neither inactivation nor afterpotential E http://flybase.org/reports/FBgn0002940 FBgn0046298 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Arr2 G-protein coupled photoreceptor activity ; GO:0008020 | non-traceable author statement G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity G-protein coupled photoreceptor activity ; GO:0008020 | inferred from mutant phenotype visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR001760 negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | inferred from mutant phenotype phototransduction ; GO:0007602 | non-traceable author statement detection of UV ; GO:0009589 | inferred from mutant phenotype phospholipase C-activating rhodopsin mediated signaling pathway ; GO:0030265 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from sequence or structural similarity thermotaxis ; GO:0043052 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype detection of visible light ; GO:0009584 | inferred from mutant phenotype response to light intensity ; GO:0009642 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype optomotor response ; GO:0071632 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity phototaxis ; GO:0042331 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR001735, InterPro:IPR001760, InterPro:IPR017452 subrhabdomeral cisterna ; GO:0016029 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay multivesicular body ; GO:0005771 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity secondary lysosome ; GO:0005767 | inferred from direct assay inaD signaling complex ; GO:0016027 | traceable author statement perinuclear endoplasmic reticulum ; GO:0097038 | colocalizes_with inferred from direct assay inaD signaling complex ; GO:0016027 | inferred from physical interaction with inaD inferred from physical interaction with trp multivesicular body ; GO:0005771 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay rough endoplasmic reticulum ; GO:0005791 | inferred from direct assay" "Rh1, 143283_at, rhodopsin, opsin, rh1, Nina E, DmRh1, Rh, FBgn0002940, rh1/ninaE, DMELRH1, Rh1/ninaE, Dm Rh1, RH1, ora, 1F9, BEST:GH11778, CG4550, ninaE, Rh-1, NinaE, R, DRh1, Rh1(ninaE), Rhodopsin-1" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001735:Opsin RH1/RH2, IPR001760:Opsin, IPR017452:GPCR, rhodopsin-like, 7TM, IPR027430:Visual pigments (opsins) retinal binding site" CG4550 11-Aug-17 DroID_v2017_08 "Drer\opn7a, Drer\rgra, Drer\opn1sw1, Drer\parietopsin, Drer\opn8b, Drer\rgrb, Drer\opn4xa, Drer\opn4a, Drer\exorh, Drer\tmtops2b, Drer\valopa, Drer\opn5, Drer\tmtops3a, Drer\opn4xb, Drer\tmtops2a, Drer\tmtopsb, Drer\tmtops3b, Drer\parapinopsinb, Drer\opn1mw4, Drer\opn7d, Drer\rrh, Drer\opn4.1, Drer\valopb, Drer\opn1mw3, Drer\opn1mw1, Drer\opn1lw1, Drer\opn6a, Drer\opn1lw2, Drer\opn8c, Drer\opn4b, Drer\rhol, Drer\opn3, Drer\opn7c, Drer\opn1sw2, Drer\opn6b, Drer\opn7b, Drer\rho, Drer\opn9" - "Cele\sro-1, Cele\tkr-1, Cele\nmur-3" "Xtro\opn1lw, Xtro\opn5, Xtro\opn4, Xtro\rrh, Xtro\LOC100124934, Xtro\tmtops, Xtro\tmtops.2, Xtro\opn1sw, Xtro\LOC100485989, Xtro\rho, Xtro\LOC100485437" "Mmus\Opn3, Mmus\Opn1mw, Mmus\Rgr, Mmus\Rho, Mmus\Opn5, Mmus\Rrh, Mmus\Opn4, Mmus\Opn1sw" "Hsap\RHO, Hsap\OPN5, Hsap\RGR, Hsap\OPN1SW, Hsap\OPN1MW2, Hsap\OPN1MW, Hsap\OPN1LW, Hsap\OPN3, Hsap\OPN1MW3, Hsap\RRH, Hsap\OPN4" " adult stage , larval stage " " eye

, adult head

, Bolwig's organ

" "neurophysiology defective,stress response defective,phototaxis defective,increased cell death,neuroanatomy defective,thermotaxis behavior defective,size defective,visual behavior defective,dominant,wild-type,recessive,temperature conditional,optomotor response defective,behavior defective,locomotor behavior defective,viable,visible" "rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere membrane,ommatidium,rhabdomere of eye photoreceptor cell,endoplasmic reticulum, with ninaE17,mitochondrion, with ninaE17,autophagic vacuole, with ninaE17,multivesicular body, with ninaE17,lysosome, with ninaE17,retina,endoplasmic reticulum,Golgi apparatus,rhabdomere,eye,photoreceptor cell & rough endoplasmic reticulum,photoreceptor cell & Golgi apparatus,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,endocytic vesicle,photoreceptor cell,eye photoreceptor cell,conditional,rhabdomere & actin filament,endoplasmic reticulum, with ninaEP37H,mitochondrion, with ninaEP37H,autophagic vacuole, with ninaEP37H,multivesicular body, with ninaEP37H,lysosome, with ninaEP37H,rhabdomere R1 & microvillus,rhabdomere R2 & microvillus,rhabdomere R3 & microvillus,rhabdomere R4 & microvillus,rhabdomere R5 & microvillus,rhabdomere R6 & microvillus,eye disc" FBgn0002121 l(2)gl lethal (2) giant larvae http://flybase.org/reports/FBgn0002121 - protein_coding_gene protein kinase inhibitor activity ; GO:0004860 | inferred from direct assay syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000028271 myosin II binding ; GO:0045159 | traceable author statement Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000028271 myosin II binding ; GO:0045159 | inferred from genetic interaction with zip myosin binding ; GO:0017022 | inferred from genetic interaction with zip SNARE binding ; GO:0000149 | inferred from physical interaction with MGI:MGI:893577 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000028271 asymmetric protein localization=0008105 |...<> basal protein localization=0045175 |... genetic interaction with jar <> apical protein localization=0045176 |...<> morphogenesis of an epithelium=0002009 | traceable author statement <> establishment of protein localization=0045184 |...<> septate junction assembly=0019991 | traceable author statement <> establishment or maintenance of neuroblast polarity=0045196 | traceable author statement <> establishment or maintenance of polarity of follicular epithelium=0016334 |... genetic interaction with dlg1 <> chitin-based larval cuticle pattern formation=0035293 |...<> establishment or maintenance of epithelial cell apical/basal polarity=0045197 | traceable author statement <> synaptic vesicle priming=0016082 | <> protein localization=0008104 | traceable author statement <> asymmetric neuroblast division=0055059 |... genetic interaction with mts <> protein localization to cell cortex=0072697 |...<> establishment or maintenance of neuroblast polarity=0045196 |... genetic interaction with aPKC <> cell proliferation=0008283 | traceable author statement <> morphogenesis of larval imaginal disc epithelium=0016335 | traceable author statement <> negative regulation of neuroblast proliferation=0007406 |...<> establishment or maintenance of polarity of embryonic epithelium=0016332 | traceable author statement <> dorsal closure=0007391 | traceable author statement <> neurotransmitter secretion=0007269 | <> cell competition in a multicellular organism=0035212 |...<> negative regulation of cell proliferation=0008285 | traceable author statement <> negative regulation of protein kinase activity=0006469 |... direct assay <> basal protein localization=0045175 |...<> actin cytoskeleton organization=0030036 |...<> asymmetric protein localization involved in cell fate determination=0045167 | traceable author statement <> regulation of cell cycle=0051726 | <> salivary gland histolysis=0035070 |...<> regulation of cell shape=0008360 | <> negative regulation of Notch signaling pathway=0045746 |... genetic interaction with N <> oocyte microtubule cytoskeleton organization=0016325 |...<> ecdysone-mediated induction of salivary gland cell autophagic cell death=0035072 |...<> germarium-derived egg chamber formation=0007293 |...<> establishment or maintenance of polarity of larval imaginal disc epithelium=0016336 | traceable author statement <> establishment of mitotic spindle orientation=0000132 |...<> nervous system development=0007399 |...<> oocyte anterior/posterior axis specification=0007314 |...<> basal protein localization=0045175 | <> establishment of epithelial cell planar polarity=0090163 |...<> establishment or maintenance of epithelial cell apical/basal polarity=0045197 | <> asymmetric protein localization involved in cell fate determination=0045167 |...inferred from physical interaction with par-6 <> transforming growth factor beta receptor signaling pathway=0007179 |...inferred from genetic interaction with dpp <> regulation of protein secretion=0050708 |... biological aspect of ancestor with PANTHER:PTN000028273 <> morphogenesis of a polarized epithelium=0001738 | traceable author statement <> morphogenesis of follicular epithelium=0016333 |...<> asymmetric protein localization=0008105 | traceable author statement <> epithelium development=0060429 |...<> symmetric cell division=0098725 |...<> sensory organ development=0007423 |...<> regulation of exocytosis=0017157 |... biological aspect of ancestor with PANTHER:PTN000028271 <> localization within membrane=0051668 |...<> epidermis morphogenesis=0048730 |...<> establishment of neuroblast polarity=0045200 | traceable author statement cell cortex ; GO:0005938 | inferred from direct assay septate junction ; GO:0005918 | non-traceable author statement smooth septate junction ; GO:0005920 | inferred from direct assay cytoskeleton ; GO:0005856 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | traceable author statement inferred from direct assay septate junction ; GO:0005918 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | inferred from direct assay cortical cytoskeleton ; GO:0030863 | inferred from direct assay synaptic vesicle ; GO:0008021 | non-traceable author statement cytosol ; GO:0005829 | traceable author statement basolateral plasma membrane ; GO:0016323 | traceable author statement cell cortex ; GO:0005938 | traceable author statement proteinaceous extracellular matrix ; GO:0005578 | inferred from direct assay "Lgl, lgl, dlgl, p127l(2)gl, LGL, l(2) giant larva, CG2671, L(2)GL, p127, l(2)giant larvae, D-LGL, l(2), gl, l[[2]]gl, l-gl, l(2)gl, L(2)gl, MENE (2L)-B, p127[l(2)gl]" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR000664:Lethal(2) giant larvae protein, IPR013577:Lethal giant larvae homologue 2, IPR013905:Lethal giant larvae (Lgl)-like, C-terminal domain" CG2671 11-Aug-17 DroID_v2017_08 "Drer\llgl2, Drer\stxbp6l, Drer\llgl1" "Scer\SRO77, Scer\SRO7" Cele\lgl-1 "Xtro\llgl2, Xtro\llgl1, Xtro\stxbp6" "Mmus\Llgl2, Mmus\Llgl1" "Hsap\LLGL1, Hsap\LLGL2" " embryonic stage , larval stage , adult stage , adult stage && oogenesis stage " " hypophysis

, ventral nerve cord commissure

, imaginal disc

, embryonic/larval salivary gland

, ventral nerve cord

, embryonic/larval fat body

, embryonic/larval proventriculus

, larval muscle system

, ring gland

, embryonic/larval hindgut

, neuroblast

, supraesophageal ganglion

, embryonic/larval salivary gland duct

, head

, epidermis

, embryonic optic lobe primordium

, pharyngeal muscle

, ovary

, longitudinal connective

, larval brain

, embryonic/larval pharynx

" "viable,neuroanatomy defective,lethal,recessive,hyperplasia,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,male sterile,maternal effect,female sterile,wild-type,lethal - all die before end of P-stage,partially,some die during pharate adult stage,tumorigenic,decreased cell number,somatic clone,neoplasia,somatic clone - Minute background,cell lethal,decreased cell size,melanotic mass phenotype,large body,cell polarity defective,cell growth defective,increased cell death,cell non-autonomous,planar polarity defective,germline clone,lethal - all die before end of pupal stage,some die during pupal stage,size defective,lethal - all die before end of embryonic stage,paternal effect,some die during embryonic stage" "oocyte nucleus,microtubule & oocytemat.‘±Tub67C.THsimVP16,epithelium,female germline cyst,type I neuroblast,supernumerary,type II neuroblast,secondary neuroblast,imaginal disc,embryonic/larval brain,eye disc,somatic clone,egg chamber,oocyte associated follicular epithelium,follicle cell,embryonic/larval salivary gland,larval brain & neuroblast | supernumerary,neuroblast & larval brain & third instar larva,wing disc,ventral thoracic disc,dorsal mesothoracic disc & epithelial cell,ventral thoracic disc & epithelial cell,border follicle cell,mechanosensory chaeta,heat sensitive,external sensory organ,male genitalia,socket,tormogen cell,eo neuron,extended germ band embryo,maternal effect,embryonic epidermis,embryonic ventral epidermis,embryonic leading edge cell,cephalopharyngeal skeleton,filzkorper,denticle belt,embryonic head,embryonic/larval midgut,germarium,ovary,pupa,nurse cell,stage S9 oocyte,oocyte,oocyte & cytoskeleton | conditional ts,nurse cell & cytoskeleton | conditional ts,optic lobe,adherens junction,embryonic/larval corpus allatum,prothoracic gland,trichogen cell,thecogen cell,epithelial cell,proximal,somatic clone - Minute background,distal,ectopic,germline clone,neuroblast,EL neuron,cuticle,wing,anterior/posterior compartment boundary,wing vein,egg,embryonic/larval lymph gland,Malpighian tubule,dorsal triple row,chemosensory ventral triple row bristle,dorsal double row,ventral double row,crossvein,embryonic/first instar larval cuticle,microtubule & oocyte | germ-line clone,cell non-autonomous,denticle,adult head,brain,embryonic/larval neuroblast,haltere disc,prothoracic leg disc,metathoracic leg disc,embryonic/larval optic lobe,larval brain | posterior & neuroblast | supernumerary,larval brain | posterior & neuron,external sensory organ precursor cell IIb,external sensory organ precursor cell IIa,endosomeneur-P72,sensory mother cell" FBgn0021760 chb chromosome bows http://flybase.org/reports/FBgn0021760 "FBgn0041101, FBgn0041587, FBgn0043506, FBgn0045153, FBgn0045266, FBgn0045320, FBgn0047200, FBgn0052435" protein_coding_gene kinetochore binding ; GO:0043515 | inferred from electronic annotation with InterPro:IPR028399 microtubule plus-end binding ; GO:0051010 | inferred from electronic annotation with InterPro:IPR028399 microtubule binding ; GO:0008017 | inferred from direct assay GTP binding ; GO:0005525 | inferred from direct assay mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype positive regulation of microtubule polymerization ; GO:0031116 | inferred from mutant phenotype mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype stem cell population maintenance ; GO:0019827 | inferred from mutant phenotype ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of mitotic centrosome separation ; GO:0046602 | inferred from mutant phenotype establishment of mitotic spindle localization ; GO:0040001 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype attachment of mitotic spindle microtubules to kinetochore ; GO:0051315 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from mutant phenotype cystoblast division ; GO:0007282 | inferred from mutant phenotype "cytoplasmic microtubule ; GO:0005881 | inferred from electronic annotation with InterPro:IPR028399 kinetochore microtubule ; GO:0005828 | inferred from electronic annotation with InterPro:IPR028399 microtubule plus-end ; GO:0035371 | inferred from direct assay spindle pole ; GO:0000922 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay spindle microtubule ; GO:0005876 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay microtubule plus-end ; GO:0035371 | inferred from mutant phenotype spindle ; GO:0005819 | colocalizes_with inferred from direct assay germline ring canal ; GO:0045172 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay microtubule organizing center ; GO:0005815 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay polar microtubule ; GO:0005827 | inferred from direct assay" "CLASP, Orbit, Mast, MAST, MAST/Orbit, Orbit/MAST, orbit, mast, orbit/MAST, orbit/mast, mast/orbit, Orbit/Mast, MESR7, DMAP160, v40, chb(v40), 0686/07, NEST:bs13a06, NEST:bs17d05, NEST:bs28g05, anon-WO0104295, CG32435, BcDNA:LD31673, chb, clasp, Chb, orb, Mast/Orbit, chb/mast/orbit, dCLASP" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024395:CLASP N-terminal domain, IPR028399:CLIP-associating protein 1, IPR034085:TOG domain, IPR021133:HEAT, type 2" CG32435 11-Aug-17 DroID_v2017_08 "Drer\clasp1b, Drer\clasp2, Drer\LOC101884241, Drer\clasp1a" Scer\STU1 "Cele\cls-2, Cele\cls-3, Cele\cls-1, Cele\C27C12.1" Xtro\clasp1 "Mmus\Clasp1, Mmus\Clasp2" "Hsap\CLASP1, Hsap\CLASP2" " adult stage | male , embryonic stage -- adult stage " organism

" embryonic stage | stage 4 , adult stage , larval stage " " ovary

, larval brain

" "female sterile,male sterile,viable,lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,fertile,mitotic cell cycle defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,sterile,aging defective,visible,maternal effect,wild-type,cell adhesion defective,cytokinesis defective" "spindle | maternal effect,centrosome | maternal effect,egg chamber,ovary,oocyte,female germline stem cell,ovariole,cystoblast,cystocyte,spindle,mitotic cell cycle,nurse cell ring canal,nurse cell,microtubule,microtubule organizing center,testis,spermatozoon,mitotic cell cycle[-],anterior fascicle & synapse,intersegmental nerve,embryonic/larval neuron,centriole,larval brain & nuclear chromosome,ganglion & mitotic cell cycle & larva,mitotic cell cycle & neuroblast,egg,maternal effect,nucleus | embryonic stage | maternal effect,mitotic cell cycle | maternal effect,mitotic cell cycle & spindle | maternal effect,mitotic cell cycle & centrosome | maternal effect,mitotic cell cycle & midbody | maternal effect,wing,eye,ommatidium,macrochaeta,mitotic metaphase,presumptive embryonic/larval central nervous system,embryonic hemocyte,nucleus & spermatocyte,Nebenkern & spermatocyte,spindle & spermatocyte,fascicle,pCC neuron,spindle microtubule & kinetochore microtubule,metaphase & condensed nuclear chromosome,anaphase & condensed nuclear chromosome,mitosis & nuclear chromosome,kinetochore,metaphase & condensed nuclear chromosome | maternal effect,chromosome, centromeric region | maternal effect,mitotic prometaphase | maternal effect,centrosome,pericentriolar material" DRSC11469 I 1.621915307 1.423389752 0.498923029 0.010602698 -0.25351616 0.697159101 FBgn0041604 dlp dally-like http://flybase.org/reports/FBgn0041604 protein_coding_gene heparan sulfate proteoglycan binding ; GO:0043395 | inferred from electronic annotation with InterPro:IPR001863 Wnt-protein binding ; GO:0017147 | inferred from direct assay detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | traceable author statement positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype inferred from genetic interaction with dally negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from expression pattern inferred from genetic interaction with wg imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with Sdc proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR001863 external side of plasma membrane ; GO:0009897 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity neuromuscular junction ; GO:0031594 | inferred from direct assay perivitelline space ; GO:0098595 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG32146, Dlp, dly, Dly, Dally-like, D-gpcB, CT16138, CG5031, CG17703, dlp, DLP" "IPR001863:Glypican, IPR011989:Armadillo-like helical" CG32146 11-Aug-17 DroID_v2017_08 "Drer\gpc1b, Drer\gpc5c, Drer\gpc6a, Drer\gpc6b, Drer\gpc1a, Drer\gpc3, Drer\gpc5b, Drer\gpc4, Drer\gpc2" - "Cele\C03H12.1, Cele\gpn-1" "Xtro\gpc4, Xtro\gpc1, Xtro\gpc5, Xtro\gpc2" "Mmus\Gpc4, Mmus\Gpc1, Mmus\Gpc5, Mmus\Gpc3, Mmus\Gpc6, Mmus\Gpc2" "Hsap\GPC3, Hsap\GPC6, Hsap\GPC4, Hsap\GPC2, Hsap\GPC5, Hsap\GPC1" "segment polarity phenotype,visible,viable,fertile,lethal,recessive,neuroanatomy defective,neurophysiology defective,partially lethal - majority die,non-rescuable maternal effect,lethal - all die before end of P-stage,some die during pharate adult stage" "denticle,ectopic,embryonic/first instar larval cuticle,wing margin bristle,supernumerary,1st posterior cell,wing,denticle belt,eye,mechanosensory chaeta,eye photoreceptor cell & axon,lamina plexus,medulla,ventral,presynaptic active zone | third instar larval stage,eye photoreceptor cell & axonfz-D21),ommatidium,interommatidial bristle,wing disc,sensory mother cell,somatic clone,wing margin,wing sensillum,presynaptic active zone | larval stageunspecified,NMJ bouton | larval stage,posterior,cell non-autonomous,chaeta" DRSC10281 IE -2.669872293 0.362497182 -2.72282976 3.668203824 -0.246759135 -0.034558914 FBgn0001319 kn knot http://flybase.org/reports/FBgn0001319 "FBgn0014142, FBgn0033967" protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003523 "segment polarity determination ; GO:0007367 | inferred from direct assay muscle cell fate specification ; GO:0042694 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype posterior head segmentation ; GO:0035289 | traceable author statement head segmentation ; GO:0035287 | inferred from mutant phenotype response to symbiont ; GO:0009608 | inferred from mutant phenotype regulation of lamellocyte differentiation ; GO:0035203 | inferred from mutant phenotype determination of muscle attachment site ; GO:0016204 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement anterior head segmentation ; GO:0035288 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype inferred from genetic interaction with ct positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement pattern specification process ; GO:0007389 | traceable author statement innate immune response ; GO:0045087 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype specification of segmental identity, intercalary segment ; GO:0035291 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype" - "Col, CG10197, col, collier, Kn, kn, Col/Kn, knot, coe, DmCOE, Knot" "IPR018350:Transcription factor COE, conserved site, IPR002909:IPT domain, IPR003523:Transcription factor COE, IPR014756:Immunoglobulin E-set, IPR013783:Immunoglobulin-like fold, IPR032200:Transcription factor COE, DNA-binding domain, IPR032201:Transcription factor COE, helix-loop-helix domain" CG10197 11-Aug-17 DroID_v2017_08 "Drer\ebf1a, Drer\ebf3b, Drer\ebf2, Drer\ebf3a, Drer\ebf1b" - Cele\unc-3 "Xtro\ebf3, Xtro\ebf2" "Mmus\Ebf3, Mmus\Ebf4, Mmus\Ebf1, Mmus\Ebf2" "Hsap\EBF1, Hsap\EBF2, Hsap\EBF3, Hsap\EBF4" " embryonic stage , larval stage | third instar " " embryonic mandibular segment

, dorsal mesothoracic disc | anterior/posterior compartment boundary | anterior to

, head mesoderm

" larval stage | third instar dorsal mesothoracic disc | anterior/posterior compartment boundary | anterior to

"neuroanatomy defective,smell perception defective,chemical sensitive,lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage,immune response defective,visible,wild-type,viable,recessive,somatic clone,lethal,cell non-autonomous" "A1-7 dorsal acute muscle 3,A1-7 dorsal acute muscle 2,ectopic,wing vein L3,wing vein L4,dendritic tree | larval stage2-21,class I dendritic arborizing neuron | larval stage,class II dendritic arborizing neuron | larval stage,class III dendritic arborizing neuron | larval stage,lateral process,abdominal 1 dorsal acute muscle 3,abdominal 2 dorsal acute muscle 3,abdominal 3 dorsal acute muscle 3,abdominal 4 dorsal acute muscle 3,abdominal 5 dorsal acute muscle 3,abdominal 6 dorsal acute muscle 3,abdominal 7 dorsal acute muscle 3,abdominal 1 dorsal oblique muscle 5,abdominal 2 dorsal oblique muscle 5,abdominal 3 dorsal oblique muscle 5,abdominal 4 dorsal oblique muscle 5,abdominal 5 dorsal oblique muscle 5,abdominal 6 dorsal oblique muscle 5,abdominal 7 dorsal oblique muscle 5,hypostomal sclerite,heat sensitive,cephalopharyngeal skeleton,1st posterior cell,wing,submarginal cell,2nd posterior cell,3rd posterior cell,wing | P-stage,wing vein,posterior crossvein,anterior crossvein,wing cell,wing basal cell 1,wing cell & wing vein L3 & wing vein L4,dorsal multidendritic neuron ddaC,somatic clone,class IV dendritic arborizing neuron,dendrite | somatic clone,embryonic head,embryonic/larval somatic muscle,mesothoracic dorsal acute muscle 4,metathoracic dorsal acute muscle 4,prohemocyte,embryonic/larval lymph gland,A1-7 lateral longitudinal muscle 1,A1-7 dorsal oblique muscle 4,A1-7 dorsal oblique muscle 5,sensillum campaniformium of dorsal radius,wing cell & wing vein L3 & wing vein L4 | somatic clone,anterior compartment,cell non-autonomous,wing margin bristle,macrochaeta,hypopharyngeal lobe,ventral arm of pharyngeal sclerite,dendritic tree | somatic clone,distal,wing vein L5,proximal,wing vein L2,class I dendritic arborizing neuron,dendrite221,dendritesmid-C161,class II dendritic arborizing neuron,class III dendritic arborizing neuron,dendritic arborizing neuron,lamellocyte,supernumerary,melanotic mass,crystal cell,posterior signalling centre of lymph gland primary lobe" FBgn0010825 Gug Grunge http://flybase.org/reports/FBgn0010825 "FBgn0011373, FBgn0011523, FBgn0020427, FBgn0024868, FBgn0035897" protein_coding_gene histone deacetylase activity ; GO:0004407 | inferred from direct assay repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with eve inferred from physical interaction with hkb DNA binding ; GO:0003677 | inferred from direct assay transcription corepressor activity ; GO:0003714 | inferred from direct assay inferred from genetic interaction with eve "imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype regulation of histone acetylation ; GO:0035065 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype inferred from physical interaction with ci eye development ; GO:0001654 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay segmentation ; GO:0035282 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with rl inferred from genetic interaction with aos inferred from genetic interaction with rho" polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "gug, Atro, atro, l(3)03928, l(3)01323, l(3)rO116, l(3)j5A3, CG6964, Gug, GUG, l(3)S146907" "IPR000949:ELM2 domain, IPR001005:SANT/Myb domain, IPR002951:Atrophin-like, IPR017884:SANT domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR009057:Homeobox domain-like" CG6964 11-Aug-17 DroID_v2017_08 "Drer\atn1, Drer\rerea, Drer\rereb" - "Cele\pqn-20, Cele\egl-27" "Xtro\rere, Xtro\atn1" "Mmus\Rere, Mmus\Atn1" "Hsap\ATN1, Hsap\RERE" "lethal,partially,heat sensitive,neuroanatomy defective,progressive,viable,fertile,increased cell death,locomotor behavior defective,behavior defective,male limited,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,recessive,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,germline clone,rescuable maternal effect,visible,somatic clone,planar polarity defective,homeotic,cell polarity defective,cell non-autonomous" "wing vein,ectopic,somatic clone,wing margin,eye,autophagic vacuoleGMR.PU,eye photoreceptor cell,drug conditional,retina,temperature conditional,progressive,leg,wing,embryonic/larval brain,embryonic abdomen,germline clone,maternal effect,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic segment,embryonic head,non-rescuable maternal effect,embryonic/first instar larval cuticle,rescuable maternal effect,ventral,leg sensillum,cell non-autonomous,leg sensillum & prothoracic femur | somatic clone,mesothoracic tibial apical bristle,prothoracic tibial apical bristle,prothoracic tarsal bristle,mesothoracic tarsal bristle,metathoracic tarsal bristle,prothoracic tibial transverse row bristle,sex comb,coxa,trochanter,femur,proximal,bract,arista,unguis,ocellar triangle,triple row,trichome of the posterior wing margin,cone cell,supernumerary,cell autonomous,ommatidium,adult thorax,egg,embryo,adult abdominal segment 6,adult abdominal segment 5,wing hair,mesothoracic tergum,rhabdomere,denticle belt,embryonic epidermis,embryonic/larval neuron,tarsal segment,interommatidial bristle,mitochondrionGMR.PU,arista lateral" FBgn0038818 Nep4 Neprilysin 4 http://flybase.org/reports/FBgn0038818 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497 metallopeptidase activity ; GO:0008237 | inferred from sequence model endopeptidase activity ; GO:0004175 | inferred from direct assay" proteolysis ; GO:0006508 | inferred from sequence model proteolysis ; GO:0006508 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay sarcoplasmic reticulum ; GO:0016529 | inferred from direct assay "CG4058, dNEP4, Nep4, nep4, DmeNEP4, NEP4, Nep4A, nep4B" "IPR018497:Peptidase M13, C-terminal domain, IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR030082:Neprilysin-21" CG4058 11-Aug-17 DroID_v2017_08 "Drer\mmel1, Drer\ece1, Drer\phex, Drer\ece2b" - "Cele\nep-11, Cele\nep-6, Cele\nep-1, Cele\nep-21, Cele\nep-2, Cele\nep-10" "Xtro\ece1, Xtro\ecel1, Xtro\mmel1, Xtro\ece2" "Mmus\Mmel1, Mmus\Ecel1, Mmus\Kel, Mmus\Phex, Mmus\Mme, Mmus\Ece1, Mmus\Ece2" "Hsap\MME, Hsap\ECE1, Hsap\ECEL1, Hsap\ECE2, Hsap\PHEX, Hsap\KEL, Hsap\MMEL1" "locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,viable" "I band | third instar larval stageMef2.5xCD,sarcomere | third instar larval stageMef2.5xCD,Z disc | third instar larval stageMef2.5xCD,embryonic/larval somatic muscle | third instar larval stage,sarcoplasmic reticulum | third instar larval stageMef2.5xCD,embryonic/larval somatic muscle | larval stage" FBgn0003502 Btk29A Btk family kinase at 29A http://flybase.org/reports/FBgn0003502 FBgn0032011 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay protein tyrosine kinase activity ; GO:0004713 | inferred from mutant phenotype protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357" "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001562 head involution ; GO:0008258 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement cellularization ; GO:0007349 | inferred from mutant phenotype imaginal disc-derived male genitalia development ; GO:0007485 | inferred from mutant phenotype peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from direct assay sensitization ; GO:0046960 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype female germline ring canal formation ; GO:0007301 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 JNK cascade ; GO:0007254 | traceable author statement salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype" apical part of cell ; GO:0045177 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 cell periphery ; GO:0071944 | inferred from direct assay germline ring canal ; GO:0045172 | inferred from direct assay "Btk29A, Tec29, CG8049, tec29, Tec, Tec29A, fic, SRC 29A, CT41718, CT2415, DTec29, DSrc28, Dsrc29A, Dsrc28C, Src29A, Dm SRC2, dsrc29A, c-src/fps, src28C, src-4, src4, src2, Src2, S13, CG18355, C-src4, C-src2, EC2-9, btk, btk29A, btk29a, btk29, Btk, Btk29a, Btk29" "IPR000719:Protein kinase domain, IPR000980:SH2 domain, IPR001452:SH3 domain, IPR001562:Zinc finger, Btk motif, IPR001849:Pleckstrin homology domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011993:PH domain-like, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG8049 11-Aug-17 DroID_v2017_08 "Drer\lck, Drer\txk, Drer\frk, Drer\src, Drer\abl1, Drer\csk, Drer\hck, Drer\btk, Drer\jak2b, Drer\si:ch73-340m8.2, Drer\matk, Drer\jak3, Drer\tec, Drer\abl2, Drer\fyna, Drer\ptk6a, Drer\fynb, Drer\jak1, Drer\ptk6b, Drer\jak2a, Drer\zgc:194282, Drer\itk, Drer\lyn, Drer\yes1" - "Cele\abl-1, Cele\src-1, Cele\Y47G6A.5, Cele\src-2" "Xtro\yes1, Xtro\tec, Xtro\fyn, Xtro\tyk2, Xtro\jak3, Xtro\src, Xtro\jak1, Xtro\jak2, Xtro\lyn, Xtro\fgr, Xtro\csk, Xtro\abl2, Xtro\btk, Xtro\lck, Xtro\abl1" "Mmus\Blk, Mmus\Tec, Mmus\Jak3, Mmus\Fgr, Mmus\Lck, Mmus\Abl1, Mmus\Fyn, Mmus\Ptk6, Mmus\Frk, Mmus\Btk, Mmus\Lyn, Mmus\Jak2, Mmus\Csk, Mmus\Abl2, Mmus\Jak1, Mmus\Src, Mmus\Matk, Mmus\Tyk2, Mmus\Itk, Mmus\Hck, Mmus\Yes1, Mmus\Txk, Mmus\Srms, Mmus\Bmx" "Hsap\LYN, Hsap\ABL2, Hsap\TXK, Hsap\TEC, Hsap\SRC, Hsap\SRMS, Hsap\JAK1, Hsap\HCK, Hsap\PTK6, Hsap\LCK, Hsap\BMX, Hsap\BTK, Hsap\BLK, Hsap\JAK3, Hsap\ABL1, Hsap\MATK, Hsap\CSK, Hsap\FYN, Hsap\YES1, Hsap\ITK, Hsap\FGR, Hsap\TYK2, Hsap\JAK2, Hsap\FRK" " prepupal stage--pupal stage , adult stage , larval stage | third instar , embryonic stage | stage 8-11 , embryonic stage | stage 12 , embryonic stage | stage 9-12 , adult stage && oogenesis stage , pupal stage , embryonic stage | stage 16-17 , embryonic stage | stage 12-14 , embryonic stage | stage 15 , embryonic stage | stage 5-6 , larval stage--pupal stage , embryonic stage | stage 5 , embryonic stage , oogenesis stage && adult stage | female , larval stage--adult stage , prepupal stage , embryonic stage | stage 1-4 , adult stage | female , embryonic stage | stage >=12 " " pupal/adult digestive system | restricted

, adult dorsal vessel

, imaginal disc

, procephalic segment

, gonad

, stomodeal invagination | anterior

, adult head

, proctodeum

, nurse cell

, imaginal disc | restricted

, epidermis

, embryonic/larval salivary gland

, trachea | restricted

, midline glial cell

, proctodeum | anlage

, gnathal segment

, embryonic/larval posterior spiracle

, mushroom body

, male genital disc | restricted

, amnioserosa | anlage

, neuron | subset

, amnioserosa

, genital disc | restricted

, ovary

, adult proventriculus

, posterior midgut proper primordium

, central nervous system

, histoblast

, ejaculatory bulb | restricted

, oocyte

,

ubiquitous , anterior midgut proper primordium

, lymph gland

, antennal lobe

, embryonic central nervous system | presumptive

, ectoderm

segmentally repeated , lamellocyte

, labral segment

" " embryonic stage | stage >=13 , embryonic stage | extended germ band , larval stage | first instar , adult stage && oogenesis stage , embryonic stage | 4-14 hr , embryonic stage | stage >=5 , embryonic stage | >=4-6 hr " " peripheral nervous system

, embryonic central nervous system

, organism | striped

, larval central nervous system

, ring canal

, organism

" "lethal,recessive,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially,short lived,mating defective,male,male sterile,behavior defective,wild-type,size defective" "spectrosomeC587,germarium,cephalopharyngeal skeleton,mouth hooks,posterior,epipharyngeal sclerite,dorsal bridge,vertical bridge,anterior,labrum,hypostomal sclerite,embryonic head,presumptive embryonic salivary gland,egg chamber,nurse cell ring canal,egg,taenidial fold,embryonic/larval trachea,embryonic/first instar larval cuticle,basal apodeme of penis,ectopic,male genitalia,posterior ejaculatory duct,female germline cell,embryonic/larval salivary gland,actin filament | embryonic stage 5 | germline clone | maternal effect,embryonic/larval posterior spiracle,germline clone,egg chamber & actin cytoskeleton | germ-line clone,karyosome,nurse cell fusome,actin filament | germline clone,salivary gland common duct primordium,actin cytoskeleton,embryonic/larval muscle system,stage S14 oocyte,wing" DRSC02008 E 0.949210601 0.550633296 1.934739552 1.40421842 0.887848136 0.650728655 FBgn0003256 rl rolled http://flybase.org/reports/FBgn0003256 "FBgn0005693, FBgn0039983, FBgn0042217, FBgn0047177, FBan0012559" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR003527, InterPro:IPR008349, InterPro:IPR017441 JUN kinase activity ; GO:0004705 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement transcription factor binding ; GO:0008134 | inferred from physical interaction with cic protein kinase binding ; GO:0019901 | inferred from physical interaction with Lk6 protein kinase binding ; GO:0019901 | inferred from physical interaction with S6kII MAP kinase activity ; GO:0004707 | inferred from sequence or structural similarity MAP kinase activity ; GO:0004707 | non-traceable author statement" "torso signaling pathway ; GO:0008293 | non-traceable author statement regulation of synapse structure or activity ; GO:0050803 | traceable author statement gastrulation ; GO:0007369 | non-traceable author statement anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement cellular response to organic substance ; GO:0071310 | inferred from biological aspect of ancestor with PANTHER:PTN001171853 protein phosphorylation ; GO:0006468 | traceable author statement cellular response to starvation ; GO:0009267 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement modulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype adherens junction maintenance ; GO:0034334 | inferred from mutant phenotype negative regulation of macroautophagy ; GO:0016242 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of wound healing ; GO:0090303 | inferred from mutant phenotype R7 cell development ; GO:0045467 | traceable author statement cellular response to arsenic-containing substance ; GO:0071243 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of heart morphogenesis ; GO:2000826 | inferred from genetic interaction with yki mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular response to reactive oxygen species ; GO:0034614 | inferred from direct assay positive regulation of photoreceptor cell differentiation ; GO:0046534 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype cellular response to cadmium ion ; GO:0071276 | inferred from direct assay transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from mutant phenotype regulation of response to drug ; GO:2001023 | inferred from mutant phenotype heart development ; GO:0007507 | non-traceable author statement negative regulation of apoptotic process ; GO:0043066 | non-traceable author statement MAPK cascade ; GO:0000165 | non-traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cell junction ; GO:0030054 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement "ERK, rl, MAPK, MAP-k, dpERK, CG12559, dERK, ERKA, D-ERK, dpErk, erk, dp-ERK, Erk, pERK, ERK-A, DERK, dpMAPK, CT39192, CT34260, mapk, EK2-1, DmERK-A, Dsor2, EY2-2, DmErk, Erk1, Mapk, DmMAPK, Erk/Map kinase, Sem, ERKa, DERK-A, SR2-1, rll, E(sina)7, rl/MAPK, DmERKA, l(2R)EMS45-39, GroupII, l(2)41Ac, Su(Raf)2B, ErkA, BcDNA:RE08694, CG18732, EC2-1, DpErk, Rl, 12559, RL, pMapK, MapK, dpERK1, DpERK, sem, SEM, pMAPK, rl/ERK, dpERk, dm-dpERK, Erk1/2, p-ERK" "IPR000719:Protein kinase domain, IPR003527:Mitogen-activated protein (MAP) kinase, conserved site, IPR008271:Serine/threonine-protein kinase, active site, IPR008349:Mitogen-activated protein (MAP) kinase, ERK1/2, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG12559 11-Aug-17 DroID_v2017_08 "Drer\mapk7, Drer\mapk14a, Drer\zgc:171775, Drer\mapk4, Drer\mapk13, Drer\mapk12b, Drer\mapk15, Drer\mapk1, Drer\mapk3, Drer\mapk14b, Drer\mapk12a, Drer\mapk11, Drer\mapk6" "Scer\FUS3, Scer\SLT2, Scer\KDX1, Scer\SMK1, Scer\KSS1, Scer\HOG1" "Cele\mpk-1, Cele\mpk-2, Cele\C05D10.2, Cele\pmk-1, Cele\pmk-2, Cele\F09C12.2" "Xtro\mapk15, Xtro\mapk7, Xtro\mapk6, Xtro\mapk12, Xtro\mapk14, Xtro\mapk11, Xtro\mapk1, Xtro\mapk4, Xtro\LOC100145045" "Mmus\Mapk1, Mmus\Mapk13, Mmus\Mapk7, Mmus\Mapk14, Mmus\Mapk3, Mmus\Mapk4, Mmus\Mapk6, Mmus\Mapk11, Mmus\Mapk15, Mmus\Mapk12" "Hsap\MAPK15, Hsap\MAPK13, Hsap\MAPK4, Hsap\MAPK11, Hsap\MAPK6, Hsap\MAPK3, Hsap\MAPK7, Hsap\MAPK12, Hsap\MAPK1, Hsap\MAPK14" embryonic stage " embryonic/larval tracheal system

, mesoderm

" "lethal,recessive,viable,visible,developmental rate defective,large body,mitotic cell cycle defective,female sterile,dominant,partially,lethal - all die before end of larval stage,some die during larval stage,visual behavior defective,maternal effect,neuroanatomy defective,neurophysiology defective,chemical sensitive,radiation sensitive,lethal - all die before end of pupal stage,some die during pupal stage,wound healing defective,increased cell number,chemical resistant,short lived,partially lethal - majority die,decreased cell size,size defective" "wing vein L5,wing vein L4,rhabdomere,ommatidium,cone cell,eye,wing blade,glial cell,trichogen cell,mesothoracic tergum,wing,wing vein,photoreceptor cell R7,supernumerary,ectopic,macrochaeta,midline glial cell,eye photoreceptor cell,embryonic abdominal segment,photoreceptor cell,imaginal disc,pigment cell,denticle belt,maternal effect,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,bouton,NMJ bouton,bract,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,wing vein L3,tracheal branch primordium,male germline cell,cyst progenitor cell,germline stem cell,adult heart muscle" DRSC07833 EK 1.253037093 -0.528349543 4.703266859 -1.315218946 -7.108172478 -4.861420244 FBgn0003861 trp transient receptor potential http://flybase.org/reports/FBgn0003861 - protein_coding_gene store-operated calcium channel activity ; GO:0015279 | traceable author statement calcium channel activity ; GO:0005262 | inferred from mutant phenotype calcium channel activity ; GO:0005262 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:P48994 calmodulin binding ; GO:0005516 | traceable author statement store-operated calcium channel activity ; GO:0015279 | non-traceable author statement light-activated ion channel activity ; GO:0010461 | inferred from direct assay calcium-release channel activity ; GO:0015278 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24008 calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity with HGNC:12333 inferred from sequence or structural similarity with MGI:MGI:109528 protein binding ; GO:0005515 | inferred from physical interaction with inaF-B protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VJJ7 identical protein binding ; GO:0042802 | inferred from physical interaction with trp protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P19334 "response to light stimulus ; GO:0009416 | traceable author statement phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity with HGNC:12333 inferred from sequence or structural similarity with MGI:MGI:109528 calcium ion transport ; GO:0006816 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from mutant phenotype phospholipase C-inhibiting G-protein coupled receptor signaling pathway ; GO:0030845 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype retina homeostasis ; GO:0001895 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype calcium ion transmembrane transport ; GO:0070588 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype light-induced release of internally sequestered calcium ion ; GO:0008377 | inferred from direct assay mitochondrion organization ; GO:0007005 | inferred from mutant phenotype cellular response to anoxia ; GO:0071454 | inferred from genetic interaction with trpl detection of light stimulus involved in sensory perception ; GO:0050962 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype rhodopsin metabolic process ; GO:0046154 | inferred from mutant phenotype manganese ion transport ; GO:0006828 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 regulation of cytosolic calcium ion concentration ; GO:0051480 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 calcium-mediated signaling ; GO:0019722 | traceable author statement" inaD signaling complex ; GO:0016027 | inferred from physical interaction with UniProtKB:Q24008 rhabdomere ; GO:0016028 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay rhabdomere ; GO:0016028 | traceable author statement integral component of membrane ; GO:0016021 | non-traceable author statement inaD signaling complex ; GO:0016027 | traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000012230 rhabdomere microvillus membrane ; GO:0035997 | inferred from direct assay cation channel complex ; GO:0034703 | inferred from physical interaction with trpl "trp, TRP, dTRP, DmTRP, dTrp, 559, CG7875, Trp, idl-B, gene B" "IPR002110:Ankyrin repeat, IPR002153:Transient receptor potential channel, canonical, IPR004729:Transient receptor potential channel, IPR005821:Ion transport domain, IPR013555:Transient receptor ion channel domain, IPR020683:Ankyrin repeat-containing domain" CG7875 11-Aug-17 DroID_v2017_08 "Drer\trpc5a, Drer\trpn1, Drer\trpc1, Drer\trpc6a, Drer\trpc2b, Drer\trpc2a, Drer\trpc7a, Drer\zgc:110224, Drer\trpc4b, Drer\trpc4a, Drer\trpc3" - "Cele\trp-1, Cele\trp-2" "Xtro\trpc2, Xtro\trpc4, Xtro\trpc5, Xtro\trpc1, Xtro\trpc6, Xtro\trpc3, Xtro\LOC100492885" "Mmus\Trpc4, Mmus\Trpc5, Mmus\Trpc7, Mmus\Trpc6, Mmus\Trpc2, Mmus\Trpc3, Mmus\Trpc1" "Hsap\TRPC5, Hsap\TRPC7, Hsap\TRPC3, Hsap\TRPC1, Hsap\TRPC4, Hsap\TRPC6" " adult stage , pupal stage | late " " ocellus

, adult head

, eye

, adult head

{ - ey } , photoreceptor cell

" " pupal stage | 75 hr , adult stage , pupal stage | >=70 hr " " adult antennal nerve

, rhabdomere

, eye

, photoreceptor cell

, antennal segment 3

, cornea

, adult head

" "neurophysiology defective,neuroanatomy defective,visual behavior defective,viable,wild-type,smell perception defective,heat sensitive,recessive,dominant,auditory perception defective,semidominant" "rhabdomere, with trp3.cHa,rhabdomere, with trp1234.cHa,photoreceptor cell,rhabdomere,eye photoreceptor cell,retina,conditional,rhabdomere | conditional,rhabdomere, with trp9,antenna,heat sensitive,photoreceptor,photoreceptor cell & axon,ommatidium,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6" FBgn0263391 hts hu li tai shao http://flybase.org/reports/FBgn0263391 protein_coding_gene - "female germline ring canal formation, actin assembly ; GO:0008302 | traceable author statement adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype fusome organization ; GO:0045478 | traceable author statement testicular fusome organization ; GO:0030724 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype female germ-line cyst formation ; GO:0048135 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype female germline ring canal formation, actin assembly ; GO:0008302 | inferred from mutant phenotype germ-line cyst formation ; GO:0048134 | traceable author statement centrosome organization ; GO:0051297 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype inferred from genetic interaction with gogo inferred from physical interaction with gogo meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype actin filament bundle organization ; GO:0061572 | inferred from mutant phenotype cystoblast division ; GO:0007282 | inferred from mutant phenotype" lipid particle ; GO:0005811 | inferred from direct assay female germline ring canal inner rim ; GO:0035183 | traceable author statement fusome ; GO:0045169 | traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay germline ring canal ; GO:0045172 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay spectrosome ; GO:0045170 | inferred from direct assay germline ring canal ; GO:0045172 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay actin filament ; GO:0005884 | colocalizes_with inferred from direct assay fusome ; GO:0045169 | spectrosome ; GO:0045170 | "CG9325, HTS, hts, Hts, Add, CG43443, HTS-RC, Hts-RC, Ovhts, adducin, 1B1, Adducin, l(2)k06121, HtsF, HtsRC, htsRC, EST D, ADD-87, Add-hts, l(2)k14523, l(2)00634, anon-EST:Posey9, l(2)01103, add-like, HTS-R1, Ovhts-RC, CG34197, add, HTS_DROME, Add1, Add2" IPR001303:Class II aldolase/adducin N-terminal CG43443 11-Aug-17 DroID_v2017_08 "Drer\add1, Drer\add3a, Drer\add2, Drer\add3b" - "Cele\add-1, Cele\add-2" "Xtro\add3, Xtro\add2, Xtro\add1" "Mmus\Add3, Mmus\Add2, Mmus\Add1" "Hsap\ADD3, Hsap\ADD2, Hsap\ADD1" " adult stage | male , adult stage && oogenesis stage | stage S7 , adult stage && oogenesis stage | stage S1-14 , pupal stage , embryonic stage | early , adult stage | female , larval stage , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S7-10 , adult stage && oogenesis stage | stage S10-14 , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage >=S10 , embryonic stage | stage 9 , embryonic stage | stage >9 , adult stage && oogenesis stage | stage S9,10 , embryonic stage | stage 2,3 , oogenesis stage | stage S7-10 , embryonic stage | stage 1,2 " " nurse cell

, oocyte

,

anterior{ 0 spir* } , ovary

{ $ swa* } ,

anterior | dorsal{ 0 capu* } , germarium region 1,2

,

anterior | gradient , oocyte | anterior

, ovary

, neuroblast

, embryonic central nervous system

,

anterior , ovary

{ 0 stau* } ,

anterior-posterior-gradient{ 0 exu* } ,

anterior | dorsal{ 0 exu* } ,

anterior | dorsal , nurse follicle cell

,

anterior | dorsal{ 0 stau* } ,oocyte | anterior " " embryonic stage , adult stage && oogenesis stage | early , adult stage && oogenesis stage | stage S1-10 , adult stage && oogenesis stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage S1-13 , adult stage && oogenesis stage | stage S11-12 , embryonic stage | stage 4-15 , adult stage && oogenesis stage | stage S1-8 , adult stage && oogenesis stage | stage S1-14 " " embryonic/larval muscle system

, embryonic central nervous system

, spectrosome &&of germarium

, oocyte

, embryonic epidermis

, fusome

, germarium region 2a && nurse cell ring canal

, nurse cell ring canal

, oocyte | anterior

,

ubiquitous , embryonic/larval digestive system

, germarium region 3 && nurse cell ring canal

, follicle cell

, germarium region 2b && nurse cell ring canal

, nurse cell

, fusome &&of germarium

" FBgn0001250 if inflated http://flybase.org/reports/FBgn0001250 - protein_coding_gene cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity extracellular matrix binding ; GO:0050840 | inferred from direct assay extracellular matrix protein binding ; GO:1990430 | contributes_to inferred from physical interaction with Tig protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with mys receptor activity ; GO:0004872 | inferred from sequence or structural similarity "cell adhesion ; GO:0007155 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | traceable author statement cell adhesion mediated by integrin ; GO:0033627 | inferred from direct assay maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from genetic interaction with mys salivary gland development ; GO:0007431 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement sarcomere organization ; GO:0045214 | inferred from mutant phenotype substrate adhesion-dependent cell spreading ; GO:0034446 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from expression pattern inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from mutant phenotype axonal defasciculation ; GO:0007414 | inferred from mutant phenotype regulation of stress fiber assembly ; GO:0051492 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from genetic interaction with sws epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement midgut development ; GO:0007494 | traceable author statement maintenance of protein location ; GO:0045185 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cell migration ; GO:0016477 | traceable author statement salivary gland morphogenesis ; GO:0007435 | inferred from genetic interaction with βTub85D muscle attachment ; GO:0016203 | inferred from genetic interaction with Grip cell-matrix adhesion ; GO:0007160 | inferred from sequence or structural similarity ventral cord development ; GO:0007419 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | non-traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype central nervous system morphogenesis ; GO:0021551 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | traceable author statement" integrin complex ; GO:0008305 | inferred from direct assay basal plasma membrane ; GO:0009925 | inferred from direct assay sarcolemma ; GO:0042383 | inferred from direct assay integrin complex ; GO:0008305 | non-traceable author statement focal adhesion ; GO:0005925 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integrin complex ; GO:0008305 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integrin complex ; GO:0008305 | traceable author statement "CG9623, alphaPS2, PS2, alpha[[PS2]], PSalpha2, CT27194, aPS2, PS2alpha, in, inf, alpha[[PS2(ms8)]], PS 2, if, alphaPS2C, alphaPS2 integrin, alpha2Int, If, ItgaPS2, alphaPS2m8, PS2(c), PS2(m8), PS2(m8)alpha, alpha-PS2" "IPR018184:Integrin alpha chain, C-terminal cytoplasmic region, conserved site, IPR000413:Integrin alpha chain, IPR013519:Integrin alpha beta-propellor, IPR013649:Integrin alpha-2, IPR032695:Integrin domain, IPR013517:FG-GAP repeat" CG9623 11-Aug-17 DroID_v2017_08 "Drer\itga2b, Drer\itgav, Drer\zmp:0000001082, Drer\itga3a, Drer\itga4, Drer\itga8, Drer\itga5, Drer\itga9, Drer\itga11a, Drer\LOC100333484, Drer\itga7" Scer\YJL132W Cele\pat-2 "Xtro\itga5, Xtro\itga2b.1, Xtro\itga2b.2, Xtro\itga8, Xtro\itgav" "Mmus\Itga2, Mmus\Itga2b, Mmus\Itga6, Mmus\Itga8, Mmus\Itga9, Mmus\Itga10, Mmus\Itgav, Mmus\Itgad, Mmus\Itga5" "Hsap\ITGA10, Hsap\ITGA5, Hsap\ITGA8, Hsap\ITGAL, Hsap\ITGA2B, Hsap\ITGA9, Hsap\ITGAV" " larval stage | third instar , embryonic stage | stage 4-13 " " peripodial epithelium

, mesoderm

, dorsal mesothoracic disc

" " embryonic stage , larval stage | third instar , embryonic stage | stage >=10 " " gonadal sheath muscle

, pharyngeal muscle

, gonad | restricted

, muscle attachment site

, dorsal mesothoracic disc

, mesoderm

, visceral mesoderm

" "visible,dominant,viable,fertile,lethal,recessive,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,poor,cold sensitive,heat sensitive,lethal - all die before end of first instar larval stage,partially lethal - majority die" "gastric caecum,ventral nerve cord,anterior midgut primordium,embryonic/larval somatic muscle,gastric caecum primordium,wing vein,crossvein,presumptive embryonic salivary gland,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic/first instar larval cuticle,dorsal,RP3 motor neuron,filopodium & abdominal ventral longitudinal muscle 3,intersegmental nerve,segmental nerve,salivary gland common duct primordium,embryonic/larval salivary gland,wing,embryonic/larval midgut,somatic muscle,embryonic/larval visceral muscle,muscle attachment site,germ layer,visceral mesoderm,extended germ band embryo,midgut constriction,somatic clone,embryonic/larval visceral branch,abdominal 2 segment border muscle,abdominal 3 segment border muscle,abdominal 4 segment border muscle,abdominal 5 segment border muscle,abdominal 6 segment border muscle,abdominal 7 segment border muscle,abdominal 2 lateral longitudinal muscle 1,abdominal 3 lateral longitudinal muscle 1,abdominal 4 lateral longitudinal muscle 1,abdominal 5 lateral longitudinal muscle 1,abdominal 6 lateral longitudinal muscle 1,abdominal 7 lateral longitudinal muscle 1,abdominal 2 ventral longitudinal muscle 1,abdominal 3 ventral longitudinal muscle 1,abdominal 4 ventral longitudinal muscle 1,abdominal 5 ventral longitudinal muscle 1,abdominal 6 ventral longitudinal muscle 1,abdominal 7 ventral longitudinal muscle 1,presumptive embryonic/larval digestive system,muscle attachment site & connecting hemi-adherens junction,muscle attachment site & muscle tendon junction,muscle attachment site & basal lamina,embryonic/larval proventriculus,proventriculus inner layer,cold sensitive,anterior crossvein,wing blade,sarcomere & somatic muscle,actin cytoskeleton | embryonic stage 17,presumptive embryonic/larval muscle system,stage S14 oocyte,hemocyte,eye,heat sensitive,muscle fiber,border follicle cell" DRSC20341 IE -2.655177078 -1.138316328 -3.709081896 -1.432004186 0.041489306 0.447050276 FBgn0260440 spdo sanpodo http://flybase.org/reports/FBgn0260440 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with numb Notch binding ; GO:0005112 | inferred from physical interaction with N sensory organ development ; GO:0007423 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype sensory organ precursor cell division ; GO:0045035 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement asymmetric cell division ; GO:0008356 | inferred from mutant phenotype heart morphogenesis ; GO:0003007 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N inferred from physical interaction with N peripheral nervous system development ; GO:0007422 | traceable author statement asymmetric cell division ; GO:0008356 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay cortical cytoskeleton ; GO:0030863 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "spdo, CG31020, Spdo, 0970/02, BcDNA:RE23355" - CG31020 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,neuroanatomy defective,visible,somatic clone,size defective,viable" "peripheral nervous system precursor cluster,peripheral nervous system precursor cluster & neuron | supernumerary,embryonic peripheral nervous system & glial cell,presumptive embryonic/larval central nervous system,neuron,cardioblast,thecogen cell & peripheral nervous system,presumptive embryonic/larval peripheral nervous system,CNS glial cell,longitudinal connective,anterior commissure,posterior commissure,abdominal dorsal bipolar neuron dbp,ectopic,dorsal multidendritic neuron,macrochaeta,somatic clone,eo neuron,chaeta,macrochaeta & mesothoracic tergum | somatic clone,GW neuron,EW1 neuron,peripheral nervous system,external sensory organ precursor cell IIb,thecogen cell,multidendritic neuron,precursor,abdominal 1 dorsal bipolar neuron dbp,abdominal 2 dorsal bipolar neuron dbp,abdominal 3 dorsal bipolar neuron dbp,abdominal 4 dorsal bipolar neuron dbp,abdominal 5 dorsal bipolar neuron dbp,abdominal 6 dorsal bipolar neuron dbp,abdominal 7 dorsal bipolar neuron dbp,abdominal 1 basiconical sensillum dbd & embryonic glial cell,abdominal 2 basiconical sensillum dbd & embryonic glial cell,abdominal 3 basiconical sensillum dbd & embryonic glial cell,abdominal 4 basiconical sensillum dbd & embryonic glial cell,abdominal 5 basiconical sensillum dbd & embryonic glial cell,abdominal 6 basiconical sensillum dbd & embryonic glial cell,abdominal 7 basiconical sensillum dbd & embryonic glial cell,external sensory organ,RP2 motor neuron,RP2sib neuron,aCC neuron,pCC neuron,dMP2 neuron,vMP2 neuron,U neuron,Usib neuron,apterous-expressing neuron of the lateral cluster of the thorax,embryonic pericardial cell,embryonic heart cardioblast,embryonic/larval neuroblast,secondary neuroblast,supernumerary,abdominal 1 dorsal oblique muscle 5,abdominal 2 dorsal oblique muscle 5,abdominal 3 dorsal oblique muscle 5,abdominal 4 dorsal oblique muscle 5,abdominal 5 dorsal oblique muscle 5,abdominal 6 dorsal oblique muscle 5,abdominal 7 dorsal oblique muscle 5,abdominal 1 dorsal acute muscle 3,abdominal 2 dorsal acute muscle 3,abdominal 3 dorsal acute muscle 3,abdominal 4 dorsal acute muscle 3,abdominal 5 dorsal acute muscle 3,abdominal 6 dorsal acute muscle 3,abdominal 7 dorsal acute muscle 3,embryonic/larval pericardial cell,scutellar bristle,external sensory organ precursor cell,ectopic | third instar larval stage,wing,wing vein,wing margin,interommatidial bristle,frontal bristle,external sensory organ precursor cell IIIb,trichogen cell,tormogen cell,mesothoracic tergum" FBgn0002783 mor moira http://flybase.org/reports/FBgn0002783 "FBgn0025464, FBgn0042208" protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V464 transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 protein binding ; GO:0005515 | inferred from physical interaction with brm inferred from physical interaction with z inferred from physical interaction with Bap60 inferred from physical interaction with Bap111 "imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with MGI:MGI:1203524 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype ATP-dependent chromatin remodeling ; GO:0043044 | inferred from sequence or structural similarity with MGI:MGI:1203524 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from genetic interaction with numb inferred from genetic interaction with brat regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from genetic interaction with CycE positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay regulation of innate immune response ; GO:0045088 | inferred from genetic interaction with Rel imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from genetic interaction with e(y)3 inferred from genetic interaction with e(y)3 inferred from genetic interaction with e(y)3 inferred from genetic interaction with e(y)3 inferred from genetic interaction with e(y)3" PBAF complex ; GO:0070604 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay brahma complex ; GO:0035060 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "MOR, BAP155, CG18740, MOR/BAP155, dmMOIRA, Moira, E(E2F)3B, Swi3D, l(3)89B1, CG4275, mor, Mor, moira, Moi, MOIRA" "IPR001005:SANT/Myb domain, IPR007526:SWIRM domain, IPR009057:Homeobox domain-like, IPR001357:BRCT domain, IPR017884:SANT domain, IPR030092:SWI/SNFcomplex subunit SMARCC2, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR032450:SMARCC, N-terminal, IPR032451:SMARCC, C-terminal, IPR032448:SMARCC, SWIRM-associated domain" CG18740 11-Aug-17 DroID_v2017_08 "Drer\smarcc1b, Drer\mysm1, Drer\smarcc2, Drer\smarcc1a" "Scer\SWI3, Scer\RSC8" Cele\swsn-1 "Xtro\smarcc1, Xtro\mysm1, Xtro\smarcc2" "Mmus\Smarcc1, Mmus\Smarcc2, Mmus\Mysm1" "Hsap\SMARCC1, Hsap\MYSM1, Hsap\SMARCC2" " embryonic stage | stage >=9 , adult stage | female , embryonic stage | early , adult stage | male , embryonic stage--pupal stage ," " ventral nerve cord

,

ubiquitous , embryonic brain

, embryonic/larval hindgut

, unfertilized egg

, embryonic/larval midgut

" " embryonic stage | early , embryonic stage | stage >=9 " "

ubiquitous , embryonic/larval hindgut

, ventral nerve cord

, embryonic brain

, embryonic/larval midgut

" "wild-type,visible,somatic clone,neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,dominant,enhancer of variegation,non-suppressor of variegation,non-enhancer of variegation,lethal - all die before end of pupal stage,some die during pupal stage,heat sensitive" "adult head,dorsal,somatic clone,ocellus,arista,eye,embryonic head,midgut constriction 1,midgut constriction 2,presumptive embryonic/larval peripheral nervous system,ventral nerve cord commissure,wing vein,ectopic,cell | somatic clone,haltere,macrochaeta & haltere | posterior | somatic clone,wing,posterior,wing margin & macrochaeta | somatic clone,prothoracic leg,mesothoracic leg,metathoracic leg,femur,tibia,tarsal segment,mesothoracic tarsal segment,anterior,sex comb,egg,germline clone,dorsal appendage,chorion | germline clone,proximal,metathoracic laterotergite,scutum,genitalia,macrochaeta,lateral process,pharyngeal bars,heat sensitive,wing margin,wing hair,wing sensillum,embryonic/larval neuroblast,ganglion mother cell,type II neuroblast,supernumerary" FBgn0051618 His2A:CG31618 His2A:CG31618 http://flybase.org/reports/FBgn0051618 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 centrosome duplication ; GO:0051298 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG31618, BEST:CK01438, His2A:CG31618" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG31618 11-Aug-17 DroID_v2017_08 "Drer\LOC100332229, Drer\si:dkey-108k21.19, Drer\si:dkey-261m9.7, Drer\h2afx, Drer\fbxl6, Drer\si:ch211-113a14.26, Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.16, Drer\si:ch211-113a14.19, Drer\zgc:101846, Drer\si:ch73-368j24.14, Drer\si:dkey-23a13.20, Drer\zgc:154164, Drer\si:ch1073-159d7.10, Drer\si:ch73-368j24.13, Drer\zgc:173652, Drer\LOC100334934, Drer\h2afy2, Drer\zgc:195633, Drer\si:dkey-108k21.15, Drer\si:ch73-36p18.5, Drer\si:ch211-113a14.7, Drer\zgc:114037, Drer\si:dkey-108k21.26, Drer\LOC570115, Drer\zgc:110434, Drer\si:ch211-113a14.11, Drer\LOC100148591, Drer\si:dkey-23a13.14, Drer\si:dkey-261m9.15, Drer\si:dkey-261m9.11, Drer\si:ch1073-159d7.11, Drer\si:dkey-261m9.18" "Scer\HTA2, Scer\HTA1" "Cele\his-68, Cele\his-12, Cele\his-61, Cele\his-3, Cele\his-7, Cele\his-43, Cele\his-16, Cele\his-53, Cele\his-21, Cele\his-57, Cele\htas-1, Cele\his-65, Cele\his-19, Cele\his-35, Cele\his-33, Cele\his-47, Cele\his-51, Cele\his-30" "Xtro\h2afy2, Xtro\h2afj, Xtro\hist1h2aa, Xtro\hist1h2aj, Xtro\hist1h2am, Xtro\h2afy, Xtro\hist1h2ah, Xtro\hist1h2ad, Xtro\h2afx" "Mmus\Hist2h2aa1, Mmus\Hist1h2ai, Mmus\Hist1h2ac, Mmus\Hist1h2ak, Mmus\H2afb1, Mmus\Hist1h2ah, Mmus\H2afj, Mmus\Hist2h2ac, Mmus\H2afy, Mmus\Hist1h2aa, Mmus\H2afy2, Mmus\Hist2h2aa2, Mmus\H2al1n, Mmus\H2al2b, Mmus\Hist3h2a, Mmus\Hist1h2ad, Mmus\Hist1h2af, Mmus\H2al1j, Mmus\Hist2h2ab, Mmus\H2afb2, Mmus\Hist1h2ab, Mmus\Hist2h3c1, Mmus\H2afx, Mmus\Hist1h2ao, Mmus\Hist1h2ae, Mmus\Gm14920, Mmus\Hist1h2ag, Mmus\H2afb3, Mmus\Hist1h2ap, Mmus\Hist1h2an, Mmus\H2al2c" "Hsap\H2AFY2, Hsap\HIST1H2AE, Hsap\H2AFB2, Hsap\HIST1H2AH, Hsap\HIST2H2AA3, Hsap\H2AFJ, Hsap\HIST1H2AC, Hsap\HIST1H2AM, Hsap\H2AFX, Hsap\HIST2H2AB, Hsap\HIST1H2AB, Hsap\HIST1H2AA, Hsap\HIST1H2AG, Hsap\HIST2H2AA4, Hsap\H2AFB1, Hsap\H2AFY, Hsap\HIST1H2AD, Hsap\HIST3H2A, Hsap\H2AFB3, Hsap\HIST1H2AK, Hsap\HIST2H2AC, Hsap\HIST1H2AL, Hsap\HIST1H2AI, Hsap\HIST1H2AJ" DRSC21264 IE -3.116072292 -3.615531647 -6.915272547 -6.035485748 -0.331966247 -1.083879001 FBgn0053900 His2B:CG33900 His2B:CG33900 http://flybase.org/reports/FBgn0053900 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33900, His2B:CG33900" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33900 11-Aug-17 DroID_v2017_08 "Drer\zgc:92591, Drer\LOC100334869, Drer\si:ch211-113a14.28, Drer\si:dkey-108k21.27, Drer\si:ch211-113a14.29, Drer\si:ch73-368j24.8, Drer\LOC100329290, Drer\si:dkey-23a13.5, Drer\si:ch1073-159d7.5, Drer\hist1h2ba, Drer\si:ch73-36p18.3, Drer\zgc:194989, Drer\hist2h2l, Drer\zgc:173585, Drer\zgc:173587, Drer\si:dkey-261m9.19, Drer\si:dkey-261m9.6, Drer\si:ch1073-159d7.13, Drer\si:dkey-23a13.16, Drer\si:ch1073-153i20.3, Drer\si:dkey-108k21.11, Drer\zgc:114046, Drer\si:dkey-23a13.1, Drer\ano9a, Drer\LOC100329560, Drer\LOC100334559, Drer\si:ch211-113a14.11" "Scer\HTB2, Scer\HTB1" "Cele\his-4, Cele\his-29, Cele\his-41, Cele\his-39, Cele\his-22, Cele\his-52, Cele\his-44, Cele\his-54, Cele\his-15, Cele\his-62, Cele\his-8, Cele\his-58, Cele\his-48, Cele\his-66, Cele\his-11, Cele\his-20, Cele\his-34" "Xtro\hist1h2bm, Xtro\LOC101734494, Xtro\LOC101731959, Xtro\LOC101735164, Xtro\LOC101731067, Xtro\LOC100492632, Xtro\LOC100487485, Xtro\LOC100495396, Xtro\LOC101731852, Xtro\LOC100486150, Xtro\LOC100498553, Xtro\LOC101733171, Xtro\LOC100497915, Xtro\LOC101734862, Xtro\LOC100497082, Xtro\LOC100496436, Xtro\LOC100498647, Xtro\hist1h2bk, Xtro\LOC100498072, Xtro\hist1h2bj, Xtro\LOC100485134, Xtro\LOC100498329, Xtro\LOC101733489, Xtro\LOC100485294, Xtro\LOC101735218, Xtro\LOC101733828, Xtro\LOC100486870, Xtro\LOC100495415, Xtro\hist2h2be, Xtro\LOC101730940, Xtro\LOC100495578, Xtro\LOC100495041, Xtro\LOC100496181, Xtro\LOC100496445" "Mmus\Hist1h2bq, Mmus\Hist2h2bb, Mmus\Hist1h2br, Mmus\Hist1h2be, Mmus\Hist1h2bf, Mmus\Hist1h2bm, Mmus\Hist1h2bb, Mmus\Hist3h2ba, Mmus\Hist1h2bg, Mmus\Hist1h2ba, Mmus\Hist2h2be, Mmus\Hist1h2bk, Mmus\1700024P04Rik, Mmus\Hist1h2bn, Mmus\Hist1h2bc, Mmus\Hist1h2bh, Mmus\Hist1h2bj, Mmus\Hist1h2bp, Mmus\H2bfm, Mmus\Hist1h2bl" "Hsap\HIST2H2BE, Hsap\HIST1H2BM, Hsap\HIST1H2BN, Hsap\HIST1H2BD, Hsap\HIST1H2BG, Hsap\HIST1H2BB, Hsap\HIST1H2BL, Hsap\HIST1H2BJ, Hsap\H2BFWT, Hsap\HIST1H2BO, Hsap\HIST1H2BC, Hsap\H2BFM, Hsap\HIST2H2BF, Hsap\HIST1H2BK, Hsap\HIST1H2BF, Hsap\HIST1H2BE, Hsap\HIST1H2BH, Hsap\HIST1H2BI, Hsap\HIST1H2BA, Hsap\HIST3H2BB" FBgn0053841 His2A:CG33841 His2A:CG33841 http://flybase.org/reports/FBgn0053841 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33841, His2A:CG33841" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33841 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.15, Drer\zgc:114037, Drer\si:ch1073-159d7.10, Drer\si:dkey-261m9.11, Drer\LOC100334934, Drer\si:ch73-36p18.5, Drer\si:ch211-113a14.19, Drer\LOC100332229, Drer\si:ch73-368j24.14, Drer\h2afx, Drer\si:dkey-261m9.15, Drer\LOC100148591, Drer\si:ch211-113a14.16, Drer\si:dkey-23a13.14, Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.7, Drer\si:ch1073-159d7.11, Drer\si:dkey-23a13.20, Drer\zgc:101846, Drer\si:dkey-108k21.26, Drer\zgc:110434, Drer\si:ch211-113a14.26, Drer\si:ch211-113a14.11, Drer\si:dkey-261m9.7, Drer\LOC570115, Drer\zgc:173652, Drer\si:ch73-368j24.13, Drer\si:dkey-261m9.18, Drer\fbxl6, Drer\si:dkey-108k21.19, Drer\zgc:154164, Drer\h2afy2, Drer\zgc:195633" "Scer\HTA1, Scer\HTA2" "Cele\his-33, Cele\his-51, Cele\his-47, Cele\his-19, Cele\his-16, Cele\his-57, Cele\htas-1, Cele\his-43, Cele\his-53, Cele\his-12, Cele\his-21, Cele\his-7, Cele\his-35, Cele\his-65, Cele\his-30, Cele\his-3, Cele\his-68, Cele\his-61" "Xtro\h2afy2, Xtro\h2afx, Xtro\hist1h2ad, Xtro\h2afj, Xtro\hist1h2aj, Xtro\hist1h2aa, Xtro\h2afy, Xtro\hist1h2am, Xtro\hist1h2ah" "Mmus\Hist1h2ai, Mmus\H2al1j, Mmus\Hist1h2ap, Mmus\Gm14920, Mmus\Hist1h2ag, Mmus\H2afy, Mmus\Hist2h2aa1, Mmus\Hist1h2an, Mmus\H2afj, Mmus\Hist1h2ad, Mmus\Hist2h2ab, Mmus\Hist2h2ac, Mmus\Hist1h2aa, Mmus\Hist1h2af, Mmus\H2al2b, Mmus\H2afb1, Mmus\H2afx, Mmus\H2al1n, Mmus\Hist3h2a, Mmus\Hist1h2ao, Mmus\Hist1h2ab, Mmus\H2afb2, Mmus\Hist1h2ac, Mmus\H2afb3, Mmus\Hist1h2ah, Mmus\Hist2h3c1, Mmus\Hist2h2aa2, Mmus\H2afy2, Mmus\Hist1h2ak, Mmus\Hist1h2ae, Mmus\H2al2c" "Hsap\HIST1H2AI, Hsap\HIST1H2AG, Hsap\H2AFJ, Hsap\HIST1H2AK, Hsap\H2AFB1, Hsap\HIST2H2AC, Hsap\HIST1H2AD, Hsap\HIST2H2AA3, Hsap\HIST2H2AB, Hsap\H2AFB2, Hsap\H2AFY2, Hsap\HIST1H2AE, Hsap\HIST3H2A, Hsap\HIST1H2AL, Hsap\HIST1H2AJ, Hsap\H2AFX, Hsap\HIST1H2AB, Hsap\HIST1H2AM, Hsap\H2AFB3, Hsap\H2AFY, Hsap\HIST2H2AA4, Hsap\HIST1H2AA, Hsap\HIST1H2AH, Hsap\HIST1H2AC" FBgn0041781 SCAR SCAR http://flybase.org/reports/FBgn0041781 protein_coding_gene "actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR003124 actin binding ; GO:0003779 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:B1Q236,UniProtKB:P55162,UniProtKB:Q8MLQ0,UniProtKB:Q9VF87,UniProtKB:Q9Y0S9 protein binding ; GO:0005515 | inferred from physical interaction with Cip4" myoblast fusion ; GO:0007520 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype inferred from genetic interaction with WASp inferred from genetic interaction with Vrp1 compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype positive regulation of lamellipodium assembly ; GO:0010592 | inferred from mutant phenotype axonal fasciculation ; GO:0007413 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype neuron migration ; GO:0001764 | inferred from mutant phenotype actin filament reorganization involved in cell cycle ; GO:0030037 | inferred from mutant phenotype female germline ring canal stabilization ; GO:0008335 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype positive regulation of actin nucleation ; GO:0051127 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype regulation of cell diameter ; GO:0060305 | inferred from mutant phenotype regulation of actin nucleation ; GO:0051125 | inferred from mutant phenotype axon extension involved in axon guidance ; GO:0048846 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from direct assay actin filament-based process ; GO:0030029 | traceable author statement actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype regulation of filopodium assembly ; GO:0051489 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype SCAR complex ; GO:0031209 | inferred from physical interaction with Hem filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay SCAR complex ; GO:0031209 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "Wave, Scar, scar, wave, l(2)k03107, WAVE, CG4636, D-SCAR, l(2)k13811, BEST:SD02991, SCAR, DmSCAR, Dscar, DWave, dWAVE, SCAR/WAVE, WAVE/SCAR" "IPR003124:WH2 domain, IPR028288:SCAR/WAVE family" CG4636 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-362m14.4, Drer\wasf3b, Drer\wasf1, Drer\wasf3a, Drer\LOC101885310, Drer\zgc:109889, Drer\wasf2" - Cele\wve-1 "Xtro\wasf2, Xtro\wasf1" "Mmus\Wasf3, Mmus\Gm732, Mmus\Wasf1, Mmus\Wasf2" "Hsap\WASF2, Hsap\WASF1, Hsap\WASF3" " embryonic stage | blastoderm , embryonic stage | late " neuron &&of embryonic central nervous system

"lethal,recessive,neuroanatomy defective,germline clone,cell migration defective,fertile,cell shape defective,sterile,dominant,visible,somatic clone,viable" "embryonic myoblast,microchaeta,dorsocentral bristle,myoblast,germline clone,RP2 motor neuron,actin cytoskeleton,nucleus | embryonic stage 4 | germline clone | non-rescuable maternal effect,ventral nerve cord,rescuable maternal effect,longitudinal connective,ventral nerve cord commissure,actin filament | embryonic stage 4 | germline clone | non-rescuable maternal effect,tract,actin cytoskeletonHml.PG,actin filament,nurse cell,nurse cell ring canal,eye,somatic clone,ommatidium,interommatidial bristle,intersegmental nerve,axon,neuromuscular junction & synapse,embryonic/larval somatic muscle,rhabdomere | adult stage | somatic clone,photoreceptor,outer photoreceptor cell,follicle cell,wing" FBgn0028360 Cdc7 Cdc7 kinase http://flybase.org/reports/FBgn0028360 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with SGD:S000002175 protein kinase activity ; GO:0004672 | inferred from direct assay receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement histone kinase activity ; GO:0035173 | inferred from direct assay" histone phosphorylation ; GO:0016572 | inferred from direct assay double-strand break repair via break-induced replication ; GO:0000727 | inferred from biological aspect of ancestor with PANTHER:PTN000747050 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000002175 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern phagocytosis ; GO:0006909 | inferred from biological aspect of ancestor with PANTHER:PTN000747050 endomitotic cell cycle ; GO:0007113 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein phosphorylation ; GO:0006468 | non-traceable author statement eggshell chorion gene amplification ; GO:0007307 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 positive regulation of DNA replication ; GO:0045740 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from biological aspect of ancestor with PANTHER:PTN000747050 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002175 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 Dbf4-dependent protein kinase complex ; GO:0031431 | inferred from direct assay "CG32742, cdc7-related, CG8655, l(1)G0149, CT25076, l(1)G0461, CG8656, anon-WO03040301.250, cdc7, L(1)G0148, Cdc7, l(1)G0148" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG32742 11-Aug-17 DroID_v2017_08 Drer\cdc7 Scer\CDC7 Cele\cdc-7 Xtro\cdc7 Mmus\Cdc7 Hsap\CDC7 "viable,fertile,lethal,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage,visible" "third instar larva,trichogen cell" FBgn0028292 ric8a ric8a http://flybase.org/reports/FBgn0028292 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000965417 guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from sequence or structural similarity with UniProtKB:Q80ZG1 G-protein alpha-subunit binding ; GO:0001965 | inferred from physical interaction with UniProtKB:P20353 guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from biological aspect of ancestor with PANTHER:PTN000965417 neuroblast division ; GO:0055057 | inferred from mutant phenotype gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from biological aspect of ancestor with PANTHER:PTN000965417 establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from mutant phenotype establishment of mitotic spindle localization ; GO:0040001 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "DmRic8, l(1)G0397, RIC-8, CG15797, ric8a, ric-8, Ric-8, ric-8a" "IPR008376:Synembryn, IPR019318:Guanine nucleotide exchange factor, Ric8, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG15797 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-195b15.7, Drer\si:dkey-94f20.4, Drer\ric8a, Drer\ric8b" - Cele\ric-8 "Xtro\ric8b, Xtro\nek6, Xtro\ric8a" "Mmus\Ric8b, Mmus\Ric8a" "Hsap\RIC8A, Hsap\RIC8B" "neuroanatomy defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,body color defective,germline clone,maternal effect" "eo neuron,ectopic,thecogen cell,spindle & external sensory organ precursor cell I,mesothoracic tergum,spindle | germline clone,gastrula embryo,germline clone,embryonic neuroblast,EL neuron,embryonic/first instar larval cuticle,maternal effect,spindle & embryonic neuroblast | maternal effect" FBgn0030011 Gbeta5 Gbeta5 http://flybase.org/reports/FBgn0030011 protein_coding_gene molecular_function ; GO:0003674 | no biological data available G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with Gβ13F plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with Gβ13F "Gbeta 5, Gbeta, Gbetagamma, G[[beta]], CG10763, Gbeta5, G[[beta5]], GNB5" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001632:G-protein, beta subunit, IPR001680:WD40 repeat, IPR016346:Guanine nucleotide-binding protein, beta subunit, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG10763 11-Aug-17 DroID_v2017_08 "Drer\gnb1a, Drer\gnb5b, Drer\gnb1b, Drer\gnb2, Drer\gnb3b, Drer\gnb3a, Drer\gnb4a, Drer\gnb5a" Scer\STE4 Cele\gpb-2 "Xtro\gnb3, Xtro\gnb5, Xtro\gnb1, Xtro\gnb4" "Mmus\Gnb4, Mmus\Gnb2, Mmus\Gnb5, Mmus\Gnb1, Mmus\Gnb3" "Hsap\GNB3, Hsap\GNB2, Hsap\GNB1, Hsap\GNB4, Hsap\GNB5" FBgn0031821 KFase Kynurenine formamidase http://flybase.org/reports/FBgn0031821 protein_coding_gene arylformamidase activity ; GO:0004061 | inferred from direct assay tryptophan catabolic process to kynurenine ; GO:0019441 | inferred from biological aspect of ancestor with PANTHER:PTN001125588 prefoldin complex ; GO:0016272 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001125588 "KFase, CG9542" "IPR029058:Alpha/Beta hydrolase fold, IPR027519:Kynurenine formamidase, vertebrates/fungi-type, IPR013094:Alpha/beta hydrolase fold-3" CG9542 11-Aug-17 DroID_v2017_08 Drer\afmid - "Cele\afmd-1, Cele\F15A8.6, Cele\afmd-2" Xtro\afmid Mmus\Afmid Hsap\AFMID viable FBgn0038747 RhoGAP92B Rho GTPase activating protein at 92B http://flybase.org/reports/FBgn0038747 protein_coding_gene phospholipid binding ; GO:0005543 | inferred from sequence or structural similarity with HGNC:29096 SH3 domain binding ; GO:0017124 | inferred from physical interaction with Cip4 GTPase activator activity ; GO:0005096 | inferred from direct assay "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 negative regulation of actin filament polymerization ; GO:0030837 | inferred from mutant phenotype cellular protein localization ; GO:0034613 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay positive regulation of BMP secretion ; GO:1900144 | inferred from mutant phenotype subsynaptic reticulum organization ; GO:1990255 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004148 neuromuscular junction ; GO:0031594 | inferred from direct assay "CG4755, RhoGAP92B, drich, dRich" "IPR000198:Rho GTPase-activating protein domain, IPR004148:BAR domain, IPR008936:Rho GTPase activation protein, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR018859:BAR domain-containing family" CG4755 11-Aug-17 DroID_v2017_08 "Drer\arhgap24, Drer\fam13b, Drer\arhgap17b, Drer\si:ch211-247j9.1, Drer\si:dkey-191m6.4, Drer\si:ch211-114m9.1, Drer\fam13a, Drer\arhgap44, Drer\sh3bp1, Drer\arhgap17a, Drer\arhgap22, Drer\arhgap25" "Scer\RGA1, Scer\RGA2" Cele\Y34B4A.8 "Xtro\fam13a, Xtro\arhgap22, Xtro\arhgap24, Xtro\fam13b, Xtro\arhgap17, Xtro\arhgap44, Xtro\arhgap25" "Mmus\Arhgap44, Mmus\Arhgap24, Mmus\Inpp5b, Mmus\Pdxp, Mmus\Arhgap22, Mmus\Arhgap17, Mmus\Fam13b, Mmus\Sh3bp1, Mmus\Arhgap25" "Hsap\ARHGAP44, Hsap\FAM13B, Hsap\ARHGAP24, Hsap\FAM13A, Hsap\ARHGAP25, Hsap\PDXP, Hsap\INPP5B, Hsap\SH3BP1, Hsap\ARHGAP17, Hsap\ARHGAP22" "viable,fertile,neuroanatomy defective,neurophysiology defective,lethal" "embryonic/larval neuromuscular junction,NMJ bouton,subsynaptic reticulum | third instar larval stage,type I bouton,presynaptic active zone | third instar larval stage,neuromuscular junction" FBgn0030077 CG15365 - http://flybase.org/reports/FBgn0030077 protein_coding_gene - - - CG15365 IPR015943:WD40/YVTN repeat-like-containing domain CG15365 11-Aug-17 DroID_v2017_08 "Drer\lzts2a, Drer\lzts3b, Drer\lzts2b, Drer\n4bp3, Drer\LOC795227, Drer\lzts1" - Cele\F35B3.7 "Xtro\n4bp3, Xtro\lzts3, Xtro\lzts1, Xtro\lzts2" "Mmus\Lzts1, Mmus\Lzts2, Mmus\Lzts3, Mmus\N4bp3" "Hsap\LZTS3, Hsap\LZTS2, Hsap\LZTS1, Hsap\N4BP3" "lethal,recessive" FBgn0015299 Ssb-c31a Single stranded-binding protein c31A http://flybase.org/reports/FBgn0015299 - protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000325022 single-stranded DNA binding ; GO:0003697 | inferred from direct assay "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay positive regulation of transcription initiation from RNA polymerase II promoter ; GO:0060261 | inferred from biological aspect of ancestor with PANTHER:PTN000325022" nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000325022 "C31A, p11, CG8396, Ssb-c31a, PC4-like, Ssb-C31a" "IPR003173:Transcriptional coactivator p15 (PC4), IPR009044:ssDNA-binding transcriptional regulator" CG8396 11-Aug-17 DroID_v2017_08 "Drer\sub1b, Drer\sub1a" Scer\SUB1 Cele\T13F2.2 Xtro\sub1 Mmus\Sub1 Hsap\SUB1 " embryonic stage , oogenesis stage && adult stage | female " ovary

"viable,fertile,visible" trichogen cell FBgn0053906 His2B:CG33906 His2B:CG33906 http://flybase.org/reports/FBgn0053906 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33906, His2B:CG33906" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33906 11-Aug-17 DroID_v2017_08 "Drer\LOC100334869, Drer\si:ch73-36p18.3, Drer\si:dkey-23a13.16, Drer\si:ch211-113a14.28, Drer\si:ch1073-159d7.5, Drer\zgc:92591, Drer\si:ch73-368j24.8, Drer\hist2h2l, Drer\si:dkey-261m9.19, Drer\LOC100334559, Drer\si:dkey-108k21.11, Drer\ano9a, Drer\zgc:114046, Drer\zgc:173585, Drer\LOC100329560, Drer\si:ch211-113a14.29, Drer\zgc:194989, Drer\si:dkey-23a13.1, Drer\LOC100329290, Drer\si:dkey-108k21.27, Drer\si:ch1073-153i20.3, Drer\zgc:173587, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.5, Drer\hist1h2ba, Drer\si:ch1073-159d7.13, Drer\si:dkey-261m9.6" "Scer\HTB1, Scer\HTB2" "Cele\his-29, Cele\his-11, Cele\his-15, Cele\his-8, Cele\his-41, Cele\his-48, Cele\his-22, Cele\his-62, Cele\his-52, Cele\his-4, Cele\his-20, Cele\his-66, Cele\his-54, Cele\his-39, Cele\his-58, Cele\his-44, Cele\his-34" "Xtro\LOC100492632, Xtro\hist1h2bk, Xtro\LOC100497082, Xtro\LOC101735218, Xtro\LOC100495415, Xtro\LOC101731959, Xtro\LOC101730940, Xtro\hist2h2be, Xtro\LOC100485294, Xtro\LOC100486150, Xtro\LOC100486870, Xtro\LOC100498072, Xtro\LOC100485134, Xtro\LOC101734494, Xtro\LOC101733489, Xtro\LOC100487485, Xtro\LOC100498329, Xtro\LOC100497915, Xtro\LOC100496445, Xtro\LOC100496436, Xtro\hist1h2bj, Xtro\LOC101734862, Xtro\LOC100495578, Xtro\LOC101731067, Xtro\LOC101733828, Xtro\LOC100495041, Xtro\hist1h2bm, Xtro\LOC101733171, Xtro\LOC101731852, Xtro\LOC100498647, Xtro\LOC100496181, Xtro\LOC100498553, Xtro\LOC101735164, Xtro\LOC100495396" "Mmus\Hist1h2bm, Mmus\Hist1h2bb, Mmus\Hist1h2br, Mmus\Hist3h2ba, Mmus\Hist1h2bg, Mmus\Hist1h2ba, Mmus\1700024P04Rik, Mmus\Hist1h2bp, Mmus\H2bfm, Mmus\Hist1h2bj, Mmus\Hist1h2bf, Mmus\Hist2h2be, Mmus\Hist1h2bh, Mmus\Hist1h2bk, Mmus\Hist1h2bn, Mmus\Hist1h2bl, Mmus\Hist1h2bc, Mmus\Hist1h2bq, Mmus\Hist2h2bb, Mmus\Hist1h2be" "Hsap\HIST1H2BH, Hsap\HIST2H2BF, Hsap\HIST1H2BM, Hsap\HIST2H2BE, Hsap\HIST1H2BN, Hsap\HIST1H2BD, Hsap\H2BFWT, Hsap\HIST1H2BF, Hsap\HIST1H2BB, Hsap\HIST1H2BK, Hsap\H2BFM, Hsap\HIST1H2BL, Hsap\HIST1H2BE, Hsap\HIST1H2BJ, Hsap\HIST1H2BO, Hsap\HIST1H2BC, Hsap\HIST1H2BA, Hsap\HIST1H2BG, Hsap\HIST1H2BI, Hsap\HIST3H2BB" FBgn0053894 His2B:CG33894 His2B:CG33894 http://flybase.org/reports/FBgn0053894 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33894, His2B:CG33894" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33894 11-Aug-17 DroID_v2017_08 "Drer\hist1h2ba, Drer\zgc:114046, Drer\si:dkey-108k21.27, Drer\si:ch1073-159d7.13, Drer\si:dkey-23a13.1, Drer\si:ch1073-159d7.5, Drer\zgc:173585, Drer\si:dkey-108k21.11, Drer\LOC100329560, Drer\LOC100334869, Drer\si:dkey-261m9.6, Drer\si:ch211-113a14.29, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.5, Drer\ano9a, Drer\zgc:194989, Drer\si:ch211-113a14.28, Drer\si:dkey-261m9.19, Drer\LOC100334559, Drer\hist2h2l, Drer\LOC100329290, Drer\zgc:173587, Drer\si:ch73-36p18.3, Drer\si:ch73-368j24.8, Drer\si:ch1073-153i20.3, Drer\si:dkey-23a13.16, Drer\zgc:92591" "Scer\HTB2, Scer\HTB1" "Cele\his-15, Cele\his-29, Cele\his-4, Cele\his-20, Cele\his-39, Cele\his-41, Cele\his-54, Cele\his-62, Cele\his-52, Cele\his-11, Cele\his-8, Cele\his-66, Cele\his-48, Cele\his-58, Cele\his-44, Cele\his-22, Cele\his-34" "Xtro\LOC100498329, Xtro\LOC100498553, Xtro\LOC101731067, Xtro\LOC101733489, Xtro\hist1h2bj, Xtro\LOC100496445, Xtro\hist1h2bm, Xtro\LOC100495415, Xtro\LOC100487485, Xtro\LOC101735218, Xtro\hist2h2be, Xtro\LOC101731959, Xtro\LOC100495396, Xtro\LOC101734862, Xtro\LOC101731852, Xtro\LOC101734494, Xtro\LOC100495578, Xtro\LOC101733171, Xtro\LOC100496181, Xtro\LOC101730940, Xtro\LOC100498647, Xtro\LOC100497915, Xtro\LOC100496436, Xtro\hist1h2bk, Xtro\LOC100497082, Xtro\LOC100485294, Xtro\LOC100492632, Xtro\LOC100486870, Xtro\LOC101733828, Xtro\LOC101735164, Xtro\LOC100485134, Xtro\LOC100498072, Xtro\LOC100486150, Xtro\LOC100495041" "Mmus\Hist1h2bk, Mmus\Hist1h2bc, Mmus\Hist1h2bb, Mmus\Hist1h2be, Mmus\H2bfm, Mmus\Hist1h2bj, Mmus\Hist2h2be, Mmus\Hist1h2bp, Mmus\Hist1h2bq, Mmus\Hist1h2br, Mmus\Hist1h2ba, Mmus\Hist1h2bh, Mmus\Hist3h2ba, Mmus\Hist1h2bm, Mmus\Hist1h2bg, Mmus\Hist1h2bl, Mmus\Hist1h2bf, Mmus\Hist1h2bn, Mmus\Hist2h2bb, Mmus\1700024P04Rik" "Hsap\HIST1H2BI, Hsap\HIST1H2BO, Hsap\HIST1H2BJ, Hsap\HIST3H2BB, Hsap\HIST1H2BC, Hsap\H2BFM, Hsap\HIST1H2BL, Hsap\HIST2H2BF, Hsap\HIST1H2BD, Hsap\HIST1H2BH, Hsap\HIST1H2BE, Hsap\HIST2H2BE, Hsap\HIST1H2BG, Hsap\HIST1H2BB, Hsap\HIST1H2BA, Hsap\HIST1H2BK, Hsap\H2BFWT, Hsap\HIST1H2BM, Hsap\HIST1H2BN, Hsap\HIST1H2BF" FBgn0053820 His2A:CG33820 His2A:CG33820 http://flybase.org/reports/FBgn0053820 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33820, His2A:CG33820" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33820 11-Aug-17 DroID_v2017_08 "Drer\LOC100148591, Drer\si:dkey-108k21.26, Drer\h2afx, Drer\zgc:173652, Drer\si:dkey-108k21.15, Drer\si:dkey-108k21.19, Drer\si:ch211-113a14.26, Drer\zgc:154164, Drer\si:ch211-113a14.16, Drer\si:dkey-261m9.7, Drer\si:dkey-261m9.15, Drer\si:dkey-261m9.18, Drer\si:dkey-23a13.20, Drer\LOC100332229, Drer\si:ch73-368j24.13, Drer\si:ch73-368j24.14, Drer\LOC100334934, Drer\h2afy2, Drer\zgc:110434, Drer\si:ch211-113a14.7, Drer\LOC570115, Drer\zgc:114037, Drer\si:ch73-36p18.5, Drer\zgc:195633, Drer\si:ch211-113a14.19, Drer\si:dkey-23a13.14, Drer\si:ch1073-159d7.10, Drer\si:dkey-261m9.11, Drer\zgc:101846, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.7, Drer\si:ch1073-159d7.11, Drer\fbxl6" "Scer\HTA2, Scer\HTA1" "Cele\htas-1, Cele\his-57, Cele\his-33, Cele\his-53, Cele\his-16, Cele\his-7, Cele\his-19, Cele\his-21, Cele\his-30, Cele\his-35, Cele\his-68, Cele\his-12, Cele\his-61, Cele\his-47, Cele\his-3, Cele\his-51, Cele\his-43, Cele\his-65" "Xtro\hist1h2ad, Xtro\hist1h2aa, Xtro\h2afy2, Xtro\hist1h2aj, Xtro\h2afx, Xtro\hist1h2ah, Xtro\hist1h2am, Xtro\h2afj, Xtro\h2afy" "Mmus\H2afj, Mmus\Hist1h2ao, Mmus\H2afy, Mmus\H2al1j, Mmus\Hist1h2af, Mmus\Hist1h2ac, Mmus\Hist1h2ad, Mmus\Hist1h2ap, Mmus\Hist1h2ah, Mmus\H2al1n, Mmus\H2afb2, Mmus\H2afb3, Mmus\Hist3h2a, Mmus\Hist1h2ab, Mmus\Hist1h2ak, Mmus\Hist1h2ag, Mmus\Hist2h2aa2, Mmus\Hist2h2ab, Mmus\H2al2c, Mmus\Hist1h2ae, Mmus\H2afy2, Mmus\Hist1h2ai, Mmus\Hist2h2ac, Mmus\Hist2h3c1, Mmus\H2afb1, Mmus\H2al2b, Mmus\Hist2h2aa1, Mmus\Hist1h2aa, Mmus\Gm14920, Mmus\Hist1h2an, Mmus\H2afx" "Hsap\HIST3H2A, Hsap\H2AFJ, Hsap\HIST2H2AC, Hsap\HIST1H2AH, Hsap\HIST1H2AG, Hsap\HIST1H2AC, Hsap\H2AFY, Hsap\H2AFB1, Hsap\H2AFB2, Hsap\H2AFY2, Hsap\HIST1H2AK, Hsap\HIST2H2AB, Hsap\HIST1H2AB, Hsap\HIST1H2AL, Hsap\HIST2H2AA4, Hsap\HIST1H2AI, Hsap\H2AFX, Hsap\HIST1H2AM, Hsap\HIST1H2AJ, Hsap\HIST2H2AA3, Hsap\HIST1H2AE, Hsap\HIST1H2AD, Hsap\HIST1H2AA, Hsap\H2AFB3" FBgn0025879 Timp Tissue inhibitor of metalloproteases http://flybase.org/reports/FBgn0025879 - protein_coding_gene metalloendopeptidase inhibitor activity ; GO:0008191 | inferred from sequence or structural similarity with HGNC:11820 metalloendopeptidase inhibitor activity ; GO:0008191 | inferred from direct assay protease binding ; GO:0002020 | inferred from biological aspect of ancestor with PANTHER:PTN000931945 "delamination ; GO:0060232 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype response to organic substance ; GO:0010033 | inferred from biological aspect of ancestor with PANTHER:PTN000931945 phototaxis ; GO:0042331 | inferred from mutant phenotype negative regulation of membrane protein ectodomain proteolysis ; GO:0051045 | inferred from biological aspect of ancestor with PANTHER:PTN000931945 wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype basement membrane organization ; GO:0071711 | inferred from mutant phenotype tracheal pit formation in open tracheal system ; GO:0035202 | inferred from mutant phenotype" proteinaceous extracellular matrix ; GO:0005578 | inferred from biological aspect of ancestor with PANTHER:PTN000931945 dendrite ; GO:0030425 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000931945 "Dtimp, timp, CG6281, dTIMP, TIMP, DTIMP, Timp" "IPR001134:Netrin domain, IPR001820:Protease inhibitor I35 (TIMP), IPR008993:Tissue inhibitor of metalloproteinases-like, OB-fold, IPR027465:Proteinase inhibitor I35b (TIMP), C-terminal" CG6281 11-Aug-17 DroID_v2017_08 "Drer\timp4a, Drer\timp2b, Drer\timp4, Drer\timp2a, Drer\si:ch73-206h6.3" - "Cele\K07C11.3, Cele\cri-2" "Xtro\timp2, Xtro\timp3" "Mmus\Timp1, Mmus\Timp2, Mmus\Timp4, Mmus\Timp3" "Hsap\TIMP3, Hsap\TIMP4, Hsap\TIMP2, Hsap\TIMP1" pupal stage salivary gland

"partially lethal - majority live,cold sensitive,semi-fertile,phototaxis defective,lethal - all die before end of pupal stage,some die during embryonic stage,some die during larval stage,partially lethal - majority die,lethal,neuroanatomy defective,viable,visible" "wing,cold sensitive,wing vein,adult abdomen,embryonic/larval transverse connective | third instar larval stage,dorsal air sac primordium | third instar larval stage,wing disc | third instar larval stage,dorsal air sac,embryonic/larval dorsal trunk,embryonic/larval dorsal branch | third instar larval stage,dendritic arborizing neuron | P-stage,embryonic/larval transverse connective,ectopic | third instar larval stage,dorsal air sac primordium,tracheal air sac,heat sensitive,dorsal air sac primordium tip cell,trachea,wing | pupal stage,leg | pupal stage,mesothoracic tergum,dorsal,basement membrane | pupal stageLsp2.PH,basement membrane | pupal stageUbx-lac1-Gal4" FBgn0034605 CG15661 - http://flybase.org/reports/FBgn0034605 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG15661 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG15661 11-Aug-17 DroID_v2017_08 "Drer\ugt5a1, Drer\ugt5b4, Drer\ugt5a5, Drer\ugt2a5, Drer\ugt5g2, Drer\ugt1ab, Drer\zgc:172315, Drer\ugt5c1, Drer\ugt5b1, Drer\ugt1b4, Drer\ugt5b6, Drer\ugt2b1, Drer\ugt5d1, Drer\ugt8, Drer\ugt1b3, Drer\ugt1b2, Drer\ugt5c3, Drer\ugt2a6, Drer\ugt1b5, Drer\ugt5c2, Drer\ugt2a2, Drer\ugt5a2, Drer\ugt1a1, Drer\ugt5b2, Drer\ugt5g1, Drer\ugt2b5, Drer\ugt1b7, Drer\ugt2b3, Drer\ugt5e1, Drer\ugt5b3, Drer\ugt2b6, Drer\ugt5f1, Drer\ugt5a4" Scer\ATG26 "Cele\ugt-24, Cele\ugt-60, Cele\ugt-29, Cele\ugt-53, Cele\ugt-5, Cele\C03A7.13, Cele\ugt-35, Cele\ugt-8, Cele\ugt-22, Cele\C03A7.12, Cele\ugt-33, Cele\ugt-20, Cele\ugt-2, Cele\ugt-25, Cele\ugt-31, Cele\F10D2.8, Cele\ugt-12, Cele\ugt-36, Cele\ugt-14, Cele\F54C1.1, Cele\ugt-9, Cele\ugt-15, Cele\ugt-54, Cele\ugt-59, Cele\ugt-45, Cele\ugt-27, Cele\ugt-41, Cele\ugt-11, Cele\ugt-57, Cele\ugt-28, Cele\C23G10.6, Cele\ugt-61, Cele\ugt-6, Cele\ugt-65, Cele\ugt-62, Cele\ugt-40, Cele\C55H1.1, Cele\ugt-1, Cele\ugt-34, Cele\ugt-43, Cele\Y43D4A.2, Cele\ugt-49, Cele\ugt-51, Cele\ugt-17, Cele\ugt-19, Cele\ugt-3, Cele\ugt-21, Cele\ugt-48, Cele\ugt-47, Cele\ugt-18, Cele\ugt-30, Cele\ugt-56, Cele\ugt-46, Cele\ugt-39, Cele\ugt-37, Cele\ugt-55, Cele\ugt-44, Cele\ugt-50, Cele\ugt-42, Cele\ugt-13, Cele\ugt-38, Cele\ugt-26, Cele\ugt-58, Cele\ugt-10, Cele\H23N18.4, Cele\K04A8.10, Cele\ugt-7, Cele\ugt-16, Cele\ugt-4, Cele\ugt-52, Cele\ugt-23, Cele\ugt-32" "Xtro\ugt2b4, Xtro\ugt2a1, Xtro\ugt1a6, Xtro\ugt8, Xtro\ugt3a2" "Mmus\Ugt1a1, Mmus\Ugt1a10, Mmus\Ugt2a2, Mmus\Ugt2b1, Mmus\Ugt1a5, Mmus\Ugt8a, Mmus\Ugt1a6b, Mmus\Ugt2a1, Mmus\Ugt2b37, Mmus\Ugt3a1, Mmus\Ugt2b38, Mmus\Ugt2b5, Mmus\Ugt1a7c, Mmus\Ugt3a2, Mmus\Ugt2b36, Mmus\Ugt2b35, Mmus\Ugt1a9, Mmus\Ugt1a2, Mmus\Ugt2b34, Mmus\Ugt2a3" "Hsap\UGT1A1, Hsap\UGT1A5, Hsap\UGT2A3, Hsap\UGT3A2, Hsap\UGT2B15, Hsap\UGT2B10, Hsap\UGT1A6, Hsap\UGT2B11, Hsap\UGT1A8, Hsap\UGT1A7, Hsap\UGT2B7, Hsap\UGT1A9, Hsap\UGT2B4, Hsap\UGT1A10, Hsap\UGT1A4, Hsap\UGT3A1, Hsap\UGT2B17, Hsap\UGT2A2, Hsap\UGT2B28, Hsap\UGT8, Hsap\UGT1A3" viable FBgn0003386 Shaw Shaker cognate w http://flybase.org/reports/FBgn0003386 FBgn0040710 protein_coding_gene "voltage-gated potassium channel activity ; GO:0005249 | inferred from electronic annotation with InterPro:IPR003968, InterPro:IPR003974, InterPro:IPR028325 voltage-gated potassium channel activity ; GO:0005249 | traceable author statement voltage-gated cation channel activity ; GO:0022843 | inferred from sequence or structural similarity with eag" protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 potassium ion transport ; GO:0006813 | traceable author statement potassium ion transport ; GO:0006813 | inferred from sequence or structural similarity with eag sleep ; GO:0030431 | inferred from mutant phenotype voltage-gated potassium channel complex ; GO:0008076 | inferred from sequence or structural similarity with eag voltage-gated potassium channel complex ; GO:0008076 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "Shaw, shaw, Shaw2, dShaw, dShaw2, CG15419, CG2822, Kv3, Kv3.1, K[[v]]3" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR003968:Potassium channel, voltage dependent, Kv, IPR003974:Potassium channel, voltage dependent, Kv3, IPR005821:Ion transport domain, IPR015572:Potassium channel, voltage dependent, Shaw, invertebrate, IPR028325:Voltage-gated potassium channel" CG2822 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-334d15.4, Drer\kcnf1b, Drer\kcng4a, Drer\si:dkey-43k4.5, Drer\kcnb1, Drer\kcng2, Drer\kcnf1a, Drer\si:rp71-39b20.4, Drer\kcnc3b, Drer\kcnc2, Drer\kcnc1a, Drer\si:dkey-201i6.2, Drer\si:dkey-192j17.1, Drer\kcnc4, Drer\kcns3b, Drer\kcng4b, Drer\kcnc1b, Drer\kcnv2b, Drer\kcnv2a, Drer\kcns3a, Drer\kcnc3a, Drer\kcnb2" - "Cele\egl-36, Cele\shw-1, Cele\shw-3" "Xtro\kcnv2, Xtro\kcns1, Xtro\kcnc4, Xtro\kcnb1, Xtro\kcng1, Xtro\kcnf1, Xtro\kcng2, Xtro\kcns3, Xtro\kcnv1, Xtro\kcng4, Xtro\kcnc2, Xtro\kcnb2" "Mmus\Kcnv2, Mmus\Kcng4, Mmus\Kcng1, Mmus\Kcnf1, Mmus\Kcng2, Mmus\Kcnc3, Mmus\Kcnb2, Mmus\Kcnb1, Mmus\Kcns1, Mmus\Kcnv1, Mmus\Kcnc2, Mmus\Kcns2, Mmus\Kcnc1, Mmus\Kcnc4, Mmus\Kcns3, Mmus\Kcng3" "Hsap\KCNV2, Hsap\KCNG1, Hsap\KCNG2, Hsap\KCNB2, Hsap\KCNS3, Hsap\KCNV1, Hsap\KCNB1, Hsap\KCNG3, Hsap\KCNG4, Hsap\KCNS2, Hsap\KCNC1, Hsap\KCNC2, Hsap\KCNC4, Hsap\KCNS1, Hsap\KCNF1, Hsap\KCNC3" " embryonic stage | late , pupal stage&&adult stage " "circadian behavior defective,circadian rhythm defective,viable,male,reduced,uncoordinated,chemical sensitive,eclosion defective,body size defective,body color defective,visible,female,neurophysiology defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,locomotor rhythm defective,short lived" "wing,adult cuticle,motor neuron | larval stage" FBgn0051105 ppk22 pickpocket 22 http://flybase.org/reports/FBgn0051105 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG31105, ppk22, FBgn0051105" IPR001873:Epithelial sodium channel CG31105 11-Aug-17 DroID_v2017_08 "Drer\asic1c, Drer\asic1a, Drer\asic4a, Drer\asic4b, Drer\asic1b, Drer\asic2" - "Cele\flr-1, Cele\delm-2, Cele\acd-4, Cele\acd-5, Cele\delm-1, Cele\acd-1, Cele\del-7, Cele\acd-2, Cele\acd-3" "Xtro\scnn1g, Xtro\asic5, Xtro\asic1, Xtro\asic4, Xtro\scnn1d, Xtro\scnn1b, Xtro\scnn1a" "Mmus\Asic4, Mmus\Scnn1a, Mmus\Scnn1g, Mmus\Asic1, Mmus\Scnn1b, Mmus\Asic3, Mmus\Asic2, Mmus\Asic5" "Hsap\SCNN1B, Hsap\SCNN1D, Hsap\SCNN1A, Hsap\ASIC4, Hsap\ASIC3, Hsap\ASIC5, Hsap\ASIC2, Hsap\ASIC1, Hsap\SCNN1G" viable FBgn0041150 hoe1 hoepel1 http://flybase.org/reports/FBgn0041150 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004680 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004680 "CG2831, hoe, CG11918, CG12787, BcDNA:GH02636, hoe1, Hoe1" IPR004680:Citrate transporter-like domain CG12787 11-Aug-17 DroID_v2017_08 Drer\oca2 - - Xtro\oca2 Mmus\Oca2 Hsap\OCA2 "viable,fertile" DRSC00333 I 1.797465676 1.084175953 0.627557262 -0.549535869 -0.938719567 1.148764125 FBgn0051002 CG31002 - http://flybase.org/reports/FBgn0051002 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 endomembrane system ; GO:0012505 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG15569, CG31002, CG31002-PA" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG31002 11-Aug-17 DroID_v2017_08 "Drer\zgc:172315, Drer\ugt2b5, Drer\ugt2a1, Drer\ugt1b2, Drer\ugt8, Drer\ugt2b6, Drer\ugt5a1, Drer\ugt5c1, Drer\ugt5b3, Drer\ugt5g2, Drer\ugt5a4, Drer\ugt1b7, Drer\ugt2a5, Drer\ugt5e1, Drer\ugt5d1, Drer\ugt5b4, Drer\ugt1b3, Drer\ugt5a2, Drer\ugt1ab, Drer\ugt5f1, Drer\ugt2a3, Drer\ugt2a2, Drer\ugt5b1, Drer\ugt2b1, Drer\ugt5g1, Drer\ugt1b4, Drer\ugt5c3, Drer\ugt2b3, Drer\ugt5c2, Drer\ugt5b2, Drer\ugt5a5, Drer\ugt1b5, Drer\ugt2a6, Drer\ugt5b6, Drer\ugt2a4" Scer\ATG26 "Cele\ugt-12, Cele\F10D2.8, Cele\ugt-58, Cele\ugt-64, Cele\K04A8.10, Cele\ugt-40, Cele\ugt-16, Cele\ugt-36, Cele\ugt-51, Cele\ugt-50, Cele\C23G10.6, Cele\ugt-62, Cele\ugt-1, Cele\ugt-7, Cele\ugt-25, Cele\ugt-26, Cele\ugt-15, Cele\ugt-32, Cele\ugt-55, Cele\ugt-39, Cele\H23N18.4, Cele\ugt-31, Cele\ugt-29, Cele\ugt-47, Cele\ugt-33, Cele\ugt-13, Cele\Y43D4A.2, Cele\ugt-9, Cele\ugt-19, Cele\ugt-46, Cele\ugt-56, Cele\ugt-65, Cele\C55H1.1, Cele\ugt-21, Cele\ugt-18, Cele\C03A7.12, Cele\ugt-52, Cele\ugt-49, Cele\ugt-38, Cele\ugt-5, Cele\F54C1.1, Cele\ugt-34, Cele\ugt-3, Cele\ugt-8, Cele\ugt-14, Cele\ugt-11, Cele\ugt-48, Cele\ugt-17, Cele\ugt-30, Cele\ugt-20, Cele\ugt-35, Cele\ugt-10, Cele\ugt-60, Cele\ugt-27, Cele\ugt-53, Cele\ugt-41, Cele\ugt-63, Cele\ugt-6, Cele\ugt-24, Cele\ugt-2, Cele\ugt-37, Cele\ugt-43, Cele\ugt-61, Cele\ugt-45, Cele\ugt-4, Cele\ugt-22, Cele\C03A7.13, Cele\ugt-54, Cele\ugt-59, Cele\ugt-23, Cele\ugt-42, Cele\ugt-44, Cele\ugt-28" "Xtro\ugt3a2, Xtro\ugt1a6, Xtro\ugt2a1, Xtro\ugt2b4, Xtro\ugt8" "Mmus\Ugt2a2, Mmus\Ugt1a2, Mmus\Ugt1a1, Mmus\Ugt2b35, Mmus\Ugt1a6b, Mmus\Ugt1a10, Mmus\Ugt2b1, Mmus\Ugt2b34, Mmus\Ugt2b36, Mmus\Ugt1a7c, Mmus\Ugt8a, Mmus\Ugt2a3, Mmus\Ugt1a9, Mmus\Ugt1a5, Mmus\Ugt2b37, Mmus\Ugt2b38, Mmus\Ugt2a1, Mmus\Ugt3a2, Mmus\Ugt2b5, Mmus\Ugt3a1" "Hsap\UGT1A1, Hsap\UGT8, Hsap\UGT2A3, Hsap\UGT2B17, Hsap\UGT2B28, Hsap\UGT2A2, Hsap\UGT2B15, Hsap\UGT1A10, Hsap\UGT2B11, Hsap\UGT2B7, Hsap\UGT2B4, Hsap\UGT1A7, Hsap\UGT1A5, Hsap\UGT1A6, Hsap\UGT2B10, Hsap\UGT1A4, Hsap\UGT1A9, Hsap\UGT1A8, Hsap\UGT3A2, Hsap\UGT3A1, Hsap\UGT1A3" viable FBgn0262801 twr twisted bristles roughened eye http://flybase.org/reports/FBgn0262801 protein_coding_gene "serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR019756, InterPro:IPR019758 peptidase activity ; GO:0008233 | inferred from biological aspect of ancestor with PANTHER:PTN002246835 peptidase activity ; GO:0008233 | inferred from sequence or structural similarity with SGD:S000001461" signal peptide processing ; GO:0006465 | inferred from sequence or structural similarity with SGD:S000001461 signal peptide processing ; GO:0006465 | inferred from biological aspect of ancestor with PANTHER:PTN002246835 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR019756, InterPro:IPR019758 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000001461 signal peptidase complex ; GO:0005787 | inferred from sequence or structural similarity with SGD:S000001461 signal peptidase complex ; GO:0005787 | inferred from biological aspect of ancestor with PANTHER:PTN002246835 endomembrane system ; GO:0012505 | inferred from direct assay" "Spase18-21, CG2358, twr, l(3)05614, EfW5, l(3)84Aa, AF160889, BcDNA:GM04682, BG:DS00004.11, Spase18/21, Ov15" "IPR015927:Peptidase S24/S26A/S26B/S26C, IPR001733:Peptidase S26B, IPR019756:Peptidase S26A, signal peptidase I, serine active site, IPR019758:Peptidase S26A, signal peptidase I, conserved site" CG2358 11-Aug-17 DroID_v2017_08 Drer\sec11a Scer\SEC11 Cele\Y54E10BR.5 "Xtro\sec11c, Xtro\sec11a" "Mmus\Sec11c, Mmus\Sec11a" "Hsap\SEC11C, Hsap\SEC11A" DRSC12491 E -0.739222115 -1.269300107 -1.631986371 0.713239402 1.140682198 0.395467034 FBgn0061209 His2B:CG17949 His2B:CG17949 http://flybase.org/reports/FBgn0061209 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "His2B:CG17949, CG17949" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG17949 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113a14.28, Drer\hist2h2l, Drer\si:ch1073-159d7.5, Drer\si:ch211-113a14.11, Drer\si:dkey-108k21.11, Drer\LOC100334869, Drer\si:ch73-368j24.8, Drer\zgc:194989, Drer\si:dkey-108k21.27, Drer\si:dkey-261m9.6, Drer\LOC100329560, Drer\zgc:92591, Drer\si:ch1073-159d7.13, Drer\zgc:173587, Drer\si:ch73-36p18.3, Drer\si:dkey-261m9.19, Drer\si:dkey-23a13.16, Drer\LOC100329290, Drer\LOC100334559, Drer\si:dkey-23a13.1, Drer\ano9a, Drer\zgc:114046, Drer\si:ch211-113a14.29, Drer\hist1h2ba" "Scer\HTB1, Scer\HTB2" "Cele\his-29, Cele\his-52, Cele\his-54, Cele\his-34, Cele\his-4, Cele\his-44, Cele\his-22, Cele\his-15, Cele\his-11, Cele\his-62, Cele\his-8, Cele\his-48, Cele\his-41, Cele\his-39, Cele\his-58, Cele\his-66, Cele\his-20" "Xtro\LOC100496436, Xtro\LOC101734494, Xtro\LOC100495041, Xtro\LOC100497915, Xtro\LOC100498329, Xtro\LOC100498072, Xtro\LOC100495415, Xtro\hist2h2be, Xtro\LOC101731959, Xtro\LOC101734862, Xtro\LOC100486870, Xtro\LOC101733489, Xtro\LOC100486150, Xtro\LOC101735164, Xtro\LOC101731067, Xtro\LOC100485294, Xtro\LOC100492632, Xtro\LOC100496445, Xtro\LOC101730940, Xtro\LOC100487485, Xtro\LOC100485134, Xtro\LOC100495396, Xtro\LOC101733171, Xtro\LOC100496181, Xtro\LOC100498647, Xtro\LOC100498553, Xtro\hist1h2bj, Xtro\LOC101735218, Xtro\LOC101731852, Xtro\LOC100495578, Xtro\hist1h2bm, Xtro\LOC100497082, Xtro\LOC101733828, Xtro\hist1h2bk" "Mmus\Hist1h2br, Mmus\Hist1h2be, Mmus\Hist1h2bg, Mmus\Hist3h2ba, Mmus\Hist1h2ba, Mmus\Hist1h2bc, Mmus\Hist1h2bf, Mmus\Hist1h2bm, Mmus\H2bfm, Mmus\Hist1h2bn, Mmus\Hist1h2bh, Mmus\Hist1h2bb, Mmus\1700024P04Rik, Mmus\Hist2h2bb, Mmus\Hist1h2bl, Mmus\Hist1h2bj, Mmus\Hist2h2be, Mmus\Hist1h2bk, Mmus\Hist1h2bp, Mmus\Hist1h2bq" "Hsap\HIST1H2BO, Hsap\HIST1H2BA, Hsap\HIST2H2BF, Hsap\HIST1H2BE, Hsap\HIST1H2BF, Hsap\HIST1H2BK, Hsap\HIST2H2BE, Hsap\H2BFWT, Hsap\H2BFM, Hsap\HIST1H2BJ, Hsap\HIST1H2BM, Hsap\HIST1H2BI, Hsap\HIST1H2BN, Hsap\HIST1H2BG, Hsap\HIST3H2BB, Hsap\HIST1H2BD, Hsap\HIST1H2BH, Hsap\HIST1H2BC, Hsap\HIST1H2BL, Hsap\HIST1H2BB" DRSC03757 IE -4.1418466 -4.75136865 -2.871391202 -8.721475461 -1.365366459 -1.42108456 FBgn0053842 His3:CG33842 His3:CG33842 http://flybase.org/reports/FBgn0053842 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33842, His3:CG33842" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33842 11-Aug-17 DroID_v2017_08 "Drer\hist2h3ca1, Drer\zgc:173552, Drer\LOC108190747, Drer\si:ch1073-429i10.3, Drer\zgc:113983, Drer\h3f3c, Drer\h3f3b.1, Drer\zgc:113984, Drer\LOC108190746, Drer\hist2h3c, Drer\cenpa, Drer\h3f3d, Drer\h3f3a, Drer\si:ch73-36p18.2" "Scer\CSE4, Scer\HHT2, Scer\HHT1" "Cele\his-27, Cele\his-59, Cele\his-6, Cele\his-55, Cele\his-69, Cele\his-17, Cele\his-2, Cele\his-49, Cele\his-45, Cele\his-25, Cele\his-63, Cele\his-71, Cele\his-72, Cele\his-32, Cele\his-13, Cele\his-42, Cele\his-74, Cele\his-9" "Xtro\hist2h3d, Xtro\cenpa, Xtro\hist2h3c, Xtro\h3f3b" "Mmus\Hist1h3a, Mmus\Hist2h3c1, Mmus\Hist1h3b, Mmus\Hist2h3b, Mmus\Cenpa, Mmus\Hist1h3h, Mmus\Hist1h3e, Mmus\Hist1h3f, Mmus\Hist1h3g, Mmus\H3f3a, Mmus\Hist2h3c2, Mmus\Hist1h3i, Mmus\Hist1h3d, Mmus\Hist1h3c, Mmus\H3f3b" "Hsap\H3F3C, Hsap\HIST1H3G, Hsap\HIST1H3J, Hsap\CENPA, Hsap\HIST1H3D, Hsap\HIST1H3C, Hsap\HIST1H3B, Hsap\HIST1H3H, Hsap\HIST2H3D, Hsap\H3F3A, Hsap\HIST2H3C, Hsap\HIST3H3, Hsap\HIST1H3A, Hsap\H3F3B, Hsap\HIST1H3I, Hsap\HIST1H3F, Hsap\HIST2H3A, Hsap\HIST1H3E" FBgn0053882 His2B:CG33882 His2B:CG33882 http://flybase.org/reports/FBgn0053882 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33882, His2B:CG33882" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33882 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-36p18.3, Drer\zgc:173587, Drer\LOC100334869, Drer\si:dkey-261m9.19, Drer\si:dkey-23a13.5, Drer\si:dkey-23a13.1, Drer\hist1h2ba, Drer\si:ch1073-153i20.3, Drer\zgc:173585, Drer\si:ch211-113a14.29, Drer\ano9a, Drer\zgc:92591, Drer\si:ch1073-159d7.13, Drer\zgc:114046, Drer\si:ch73-368j24.8, Drer\si:dkey-108k21.11, Drer\LOC100334559, Drer\hist2h2l, Drer\zgc:194989, Drer\si:dkey-261m9.6, Drer\LOC100329560, Drer\si:dkey-108k21.27, Drer\LOC100329290, Drer\si:ch1073-159d7.5, Drer\si:ch211-113a14.28, Drer\si:dkey-23a13.16, Drer\si:ch211-113a14.11" "Scer\HTB1, Scer\HTB2" "Cele\his-58, Cele\his-44, Cele\his-62, Cele\his-54, Cele\his-4, Cele\his-66, Cele\his-29, Cele\his-41, Cele\his-48, Cele\his-20, Cele\his-39, Cele\his-52, Cele\his-15, Cele\his-22, Cele\his-11, Cele\his-8, Cele\his-34" "Xtro\LOC100495041, Xtro\LOC101731959, Xtro\LOC100486150, Xtro\LOC100495396, Xtro\hist1h2bm, Xtro\hist1h2bk, Xtro\LOC100495415, Xtro\LOC100496436, Xtro\LOC100487485, Xtro\LOC100498553, Xtro\LOC100496445, Xtro\LOC101735218, Xtro\LOC100485294, Xtro\LOC100497082, Xtro\LOC101733489, Xtro\LOC100498647, Xtro\LOC100498072, Xtro\LOC100486870, Xtro\LOC101731067, Xtro\LOC100492632, Xtro\LOC101735164, Xtro\hist1h2bj, Xtro\LOC101734494, Xtro\LOC100498329, Xtro\LOC100497915, Xtro\LOC101733828, Xtro\LOC101734862, Xtro\LOC101733171, Xtro\LOC100496181, Xtro\LOC100485134, Xtro\LOC100495578, Xtro\LOC101731852, Xtro\LOC101730940, Xtro\hist2h2be" "Mmus\Hist1h2bn, Mmus\Hist1h2bf, Mmus\Hist2h2bb, Mmus\1700024P04Rik, Mmus\Hist1h2bl, Mmus\H2bfm, Mmus\Hist1h2bp, Mmus\Hist1h2bj, Mmus\Hist1h2bq, Mmus\Hist3h2ba, Mmus\Hist1h2bm, Mmus\Hist1h2bg, Mmus\Hist1h2bc, Mmus\Hist1h2bk, Mmus\Hist1h2ba, Mmus\Hist2h2be, Mmus\Hist1h2be, Mmus\Hist1h2bb, Mmus\Hist1h2bh, Mmus\Hist1h2br" "Hsap\HIST1H2BE, Hsap\H2BFWT, Hsap\HIST1H2BA, Hsap\HIST1H2BF, Hsap\HIST2H2BE, Hsap\HIST1H2BL, Hsap\HIST1H2BJ, Hsap\HIST1H2BD, Hsap\HIST1H2BI, Hsap\HIST1H2BB, Hsap\HIST1H2BH, Hsap\HIST3H2BB, Hsap\HIST2H2BF, Hsap\HIST1H2BG, Hsap\HIST1H2BN, Hsap\HIST1H2BM, Hsap\H2BFM, Hsap\HIST1H2BO, Hsap\HIST1H2BC, Hsap\HIST1H2BK" FBgn0083963 Nlg3 Neuroligin 3 http://flybase.org/reports/FBgn0083963 protein_coding_gene neurexin family protein binding ; GO:0042043 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neurogenesis ; GO:0022008 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 phagocytosis ; GO:0006909 | inferred from mutant phenotype synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 "CG32465, CG18291, CG14597, CG1062, CG34127, DNLG3, DNlg3, Nlg3, dnlg3" "IPR019819:Carboxylesterase type B, conserved site, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029058:Alpha/Beta hydrolase fold, IPR002018:Carboxylesterase, type B" CG34127 11-Aug-17 DroID_v2017_08 "Drer\nlgn1, Drer\ces3, Drer\cell, Drer\si:ch211-93f2.1, Drer\nlgn3a, Drer\nlgn4b, Drer\nlgn2b, Drer\nlgn4a, Drer\nlgn3b, Drer\cel.1, Drer\ces2, Drer\nlgn2a" - "Cele\ZC376.3, Cele\ZK994.1, Cele\ZC376.1, Cele\nlg-1, Cele\T02B5.1, Cele\glit-1, Cele\W02B12.4, Cele\T02B5.3, Cele\Y75B8A.3, Cele\ZC376.2" "Xtro\nlgn4x, Xtro\nlgn3, Xtro\cel, Xtro\ces2, Xtro\ces3, Xtro\LOC100494782, Xtro\nlgn2" "Mmus\Ces1g, Mmus\Ces4a, Mmus\Ces3a, Mmus\Ces2f, Mmus\Ces3b, Mmus\Ces1c, Mmus\Ces2e, Mmus\Ces1f, Mmus\Ces1h, Mmus\Ces1b, Mmus\Ces2c, Mmus\Nlgn1, Mmus\Ces2g, Mmus\Ces1e, Mmus\Ces2h, Mmus\Ces1d, Mmus\Ces5a, Mmus\Nlgn3, Mmus\Cel, Mmus\Ces2a, Mmus\Ces2b, Mmus\Nlgn2" "Hsap\NLGN4Y, Hsap\CES5A, Hsap\CES4A, Hsap\CES2, Hsap\NLGN1, Hsap\NLGN3, Hsap\NLGN4X, Hsap\NLGN2, Hsap\CES3, Hsap\CES1, Hsap\CEL" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,viable" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0030775 CG9673 - http://flybase.org/reports/FBgn0030775 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH81, CG9673" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG9673 11-Aug-17 DroID_v2017_08 "Drer\zgc:55888, Drer\zmp:0000001114, Drer\tmprss9, Drer\st14a, Drer\LOC560023" - - - "Mmus\Egfbp2, Mmus\Klk1b3, Mmus\Gzmm, Mmus\St14, Mmus\Klk14, Mmus\Gzma, Mmus\Tmprss13" "Hsap\GZMA, Hsap\TMPRSS13, Hsap\TPSD1, Hsap\GZMM, Hsap\ST14" viable FBgn0029870 Marf Mitochondrial assembly regulatory factor http://flybase.org/reports/FBgn0029870 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR030381 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000049197 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with UniProtKB:O18412 lipid particle organization ; GO:0034389 | inferred from mutant phenotype axonal transport of mitochondrion ; GO:0019896 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype mitochondrial fusion ; GO:0008053 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype mitochondrial fusion ; GO:0008053 | inferred from sequence or structural similarity with UniProtKB:O18412 regulation of mitochondrial fission ; GO:0090140 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype positive regulation of mitochondrial fusion ; GO:0010636 | inferred from mutant phenotype mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity with UniProtKB:O18412 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000825684 intrinsic component of mitochondrial outer membrane ; GO:0031306 | inferred from biological aspect of ancestor with PANTHER:PTN000825684 "Mfn, Marf, CG3869, dmfn, anon-WO0125274.3, MARF, mfn, dMfn, marf, mfn2, dMFN, Marf-1, CG38869, Mfn-2, dMfn2" "IPR006884:Fzo/mitofusin HR2 domain, IPR022812:Dynamin superfamily, IPR030381:Dynamin-type guanine nucleotide-binding (G) domain, IPR027088:Mitofusin-1, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3869 11-Aug-17 DroID_v2017_08 "Drer\mfn1a, Drer\LOC108179028, Drer\mfn2, Drer\mfn1b" Scer\FZO1 Cele\fzo-1 "Xtro\mfn2, Xtro\mfn1" "Mmus\Mfn1, Mmus\Mfn2" "Hsap\MFN2, Hsap\MFN1" "neuroanatomy defective,cell death defective,viable,visible,increased cell number,lethal - all die during second instar larval stage,stress response defective,lethal - all die during pupal stage,partially lethal - majority die,some die during pupal stage,locomotor behavior defective,gravitaxis defective,progressive,lethal - all die before end of larval stage,some die during larval stage" "mitochondrionMef2.PR,mitochondrial cristaMef2.PR,adult brain,mitochondrionelav.PU,mitochondrionMhc.PW,trichogen cell,lamellocyte | third instar larval stage,mitochondrion | larval stagetub.PU,endoplasmic reticulum | larval stagetub.PU,mitochondrion | larval stageelav.PLu,endoplasmic reticulum | larval stageelav.PLu,mitochondrion | larval stageMef2.PR,sarcoplasmic reticulum | larval stageMef2.PR,adult heart,cardial cell,mitochondriontin.C‘î4,mitochondrion | adult stagetin.C‘î4,cardial cell | adult stage,eye,ommatidium,mitochondrion & dopaminergic neuronple.PF,indirect flight muscle" FBgn0267390 dop drop out http://flybase.org/reports/FBgn0267390 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR015022 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR015022 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence model protein kinase activity ; GO:0004672 | inferred from mutant phenotype protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" "regulation of interleukin-12 biosynthetic process ; GO:0045075 | inferred from electronic annotation with InterPro:IPR028779 wing disc development ; GO:0035220 | inferred from mutant phenotype positive regulation of ATP-dependent microtubule motor activity, minus-end-directed ; GO:2000579 | inferred from mutant phenotype lipid particle transport along microtubule ; GO:0031887 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from genetic interaction with gig border follicle cell migration ; GO:0007298 | inferred from mutant phenotype dosage compensation by hyperactivation of X chromosome ; GO:0009047 | inferred from genetic interaction with roX2, roX1 cellularization ; GO:0007349 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 endosome organization ; GO:0007032 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay "dop, CG6498, MAST205, MAST 205" "IPR000719:Protein kinase domain, IPR001478:PDZ domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR015022:Microtubule-associated serine/threonine-protein kinase, domain, IPR000961:AGC-kinase, C-terminal, IPR023142:Microtubule-associated serine/threonine-protein kinase, pre-PK domain, IPR028779:Microtubule-associated serine/threonine-protein kinase 2" CG6498 11-Aug-17 DroID_v2017_08 "Drer\mast3b, Drer\mast4, Drer\mast1b, Drer\mast3, Drer\mast1a, Drer\mast2" "Scer\KIN82, Scer\FPK1" "Cele\kin-4, Cele\W04B5.5" "Xtro\mast1, Xtro\mast4, Xtro\mast2, Xtro\mast3" "Mmus\Mast2, Mmus\Mast1, Mmus\Mast3, Mmus\Mast4" "Hsap\MAST2, Hsap\MAST4, Hsap\MAST1, Hsap\MAST3" DRSC10655 IE 1.477105096 1.79529277 1.51488682 0.462284483 0.112895948 0.668104481 FBgn0053859 His2A:CG33859 His2A:CG33859 http://flybase.org/reports/FBgn0053859 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33859, His2A:CG33859" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33859 11-Aug-17 DroID_v2017_08 "Drer\mid1ip1l, Drer\zgc:114037, Drer\si:ch73-368j24.13, Drer\zgc:154164, Drer\si:ch211-113a14.16, Drer\LOC100148591, Drer\h2afy2, Drer\si:dkey-261m9.18, Drer\si:dkey-108k21.19, Drer\si:dkey-108k21.15, Drer\si:dkey-23a13.14, Drer\zgc:195633, Drer\si:ch73-36p18.5, Drer\fbxl6, Drer\LOC100332229, Drer\si:dkey-23a13.20, Drer\si:ch73-368j24.15, Drer\si:ch73-368j24.14, Drer\zgc:101846, Drer\si:dkey-23a13.7, Drer\si:dkey-261m9.7, Drer\si:ch211-113a14.11, Drer\h2afx, Drer\si:ch1073-159d7.11, Drer\si:ch211-113a14.19, Drer\si:ch211-113a14.7, Drer\si:dkey-261m9.11, Drer\si:ch1073-159d7.10, Drer\zgc:173652, Drer\LOC100334934, Drer\LOC570115, Drer\si:dkey-261m9.15, Drer\si:ch211-113a14.26, Drer\zgc:110434, Drer\si:dkey-108k21.26" "Scer\HTA2, Scer\HTA1" "Cele\his-51, Cele\his-30, Cele\his-43, Cele\htas-1, Cele\his-68, Cele\his-21, Cele\his-7, Cele\his-19, Cele\his-35, Cele\his-33, Cele\his-12, Cele\his-53, Cele\his-16, Cele\his-61, Cele\his-65, Cele\his-57, Cele\his-3, Cele\his-47" "Xtro\LOC100496244, Xtro\LOC101734842, Xtro\LOC100494316, Xtro\h2afj, Xtro\h2afy, Xtro\LOC101731908, Xtro\LOC101730371, Xtro\LOC100496440, Xtro\LOC100492975, Xtro\LOC100488903, Xtro\LOC101732823, Xtro\LOC100492813, Xtro\LOC101731897, Xtro\hist2h2ab, Xtro\LOC100489065, Xtro\LOC100492873, Xtro\hist1h2aa, Xtro\hist1h2ad, Xtro\LOC100488021, Xtro\LOC100488074, Xtro\LOC101735111, Xtro\LOC101730817, Xtro\LOC100495988, Xtro\LOC100491383, Xtro\h2afx, Xtro\LOC101731006, Xtro\LOC101730761, Xtro\LOC100485854, Xtro\hist1h2aj, Xtro\LOC100486672, Xtro\LOC100495187, Xtro\LOC100497241, Xtro\LOC100485548, Xtro\LOC100485081, Xtro\LOC101730347, Xtro\LOC101732908, Xtro\hist1h2am, Xtro\LOC100487455, Xtro\LOC101735276, Xtro\LOC101734900, Xtro\h2afy2, Xtro\hist1h2ah, Xtro\LOC101733880, Xtro\LOC100496089, Xtro\LOC100497614, Xtro\LOC101731295, Xtro\LOC101732059, Xtro\LOC100487632, Xtro\LOC100496919, Xtro\LOC101733986, Xtro\LOC100487588, Xtro\LOC101734285, Xtro\LOC100495625, Xtro\LOC101733262, Xtro\LOC100486008, Xtro\LOC100487067, Xtro\LOC100496752, Xtro\LOC100493706, Xtro\LOC101733656" "Mmus\H2afj, Mmus\Hist2h3c1, Mmus\Hist1h2ak, Mmus\H2afb1, Mmus\Hist1h2ac, Mmus\Hist2h2ab, Mmus\Gm14920, Mmus\Hist1h2ao, Mmus\Hist1h2ah, Mmus\H2afy2, Mmus\Hist1h2ad, Mmus\Hist2h2aa1, Mmus\Hist1h2ai, Mmus\Hist1h2af, Mmus\H2afb2, Mmus\H2al2c, Mmus\H2afb3, Mmus\Hist1h2aa, Mmus\Hist1h2ap, Mmus\H2afx, Mmus\H2afy, Mmus\Hist1h2ae, Mmus\Hist1h2ag, Mmus\Hist2h2aa2, Mmus\H2al1j, Mmus\H2al1n, Mmus\Hist3h2a, Mmus\Hist1h2an, Mmus\Hist1h2ab, Mmus\Hist2h2ac, Mmus\H2al2b" "Hsap\HIST1H2AE, Hsap\HIST1H2AK, Hsap\H2AFB3, Hsap\HIST1H2AL, Hsap\HIST3H2A, Hsap\HIST1H2AA, Hsap\HIST1H2AB, Hsap\HIST1H2AJ, Hsap\HIST1H2AD, Hsap\HIST2H2AB, Hsap\HIST2H2AA4, Hsap\H2AFB2, Hsap\HIST1H2AG, Hsap\HIST2H2AC, Hsap\HIST2H2AA3, Hsap\HIST1H2AM, Hsap\HIST1H2AC, Hsap\H2AFY2, Hsap\HIST1H2AH, Hsap\H2AFB1, Hsap\H2AFX, Hsap\H2AFY, Hsap\HIST1H2AI, Hsap\H2AFJ" FBgn0264975 Nrg Neuroglian http://flybase.org/reports/FBgn0264975 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from direct assay "septate junction assembly ; GO:0019991 | inferred from mutant phenotype imaginal disc morphogenesis ; GO:0007560 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype neuron cell-cell adhesion ; GO:0007158 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype female courtship behavior ; GO:0008050 | inferred from mutant phenotype regulation of female receptivity ; GO:0045924 | non-traceable author statement nerve maturation ; GO:0021682 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype female courtship behavior ; GO:0008050 | traceable author statement male courtship behavior ; GO:0008049 | inferred from mutant phenotype axon ensheathment ; GO:0008366 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype central complex development ; GO:0048036 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype" cytoneme ; GO:0035230 | colocalizes_with inferred from direct assay septate junction ; GO:0005918 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay lateral plasma membrane ; GO:0016328 | traceable author statement pleated septate junction ; GO:0005919 | inferred from direct assay filopodium ; GO:0030175 | inferred from direct assay "Nrg, nrg, NFASC, Nrg167, Nrg180, ceb, NRG, CT4318, Ngl, CG1634, RA35, l(1)G0099, l(1)G0413, l(1)G0488, l(1)7Fa, fs(1)M72, ibx" "IPR026966:Neurofascin/L1/NrCAM, C-terminal domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013151:Immunoglobulin, IPR013098:Immunoglobulin I-set" CG1634 11-Aug-17 DroID_v2017_08 "Drer\lifrb, Drer\nadl1.2, Drer\cntn2, Drer\il12rb2l, Drer\cntn3a.2, Drer\cntn3b, Drer\nadl1.1, Drer\cntn3a.1, Drer\osmr, Drer\il6st, Drer\chl1a, Drer\nfascb, Drer\cntn5, Drer\il12rb2, Drer\chl1b, Drer\nrcamb, Drer\nrcama, Drer\nfasca, Drer\cntn4" - "Cele\lad-2, Cele\unc-89, Cele\sax-7, Cele\egl-15" "Xtro\nfasc, Xtro\l1cam, Xtro\il6st, Xtro\cntn2, Xtro\cntn1, Xtro\lifr, Xtro\nrcam, Xtro\cntn5, Xtro\osmr" "Mmus\Il27ra, Mmus\L1cam, Mmus\Osmr, Mmus\Col7a1, Mmus\Vsig10, Mmus\Cntn6, Mmus\Chl1, Mmus\Cntn3, Mmus\Tnn, Mmus\Nfasc, Mmus\Cntn1, Mmus\Col14a1, Mmus\Lifr, Mmus\Il12rb2, Mmus\Nrcam, Mmus\Cntn2, Mmus\Il6st, Mmus\Cntn4" "Hsap\IL31RA, Hsap\IL27RA, Hsap\VSIG10, Hsap\IL12RB2, Hsap\CNTN1, Hsap\CNTN5, Hsap\CNTN3, Hsap\COL14A1, Hsap\IL6ST, Hsap\CNTN6, Hsap\NRCAM, Hsap\CNTN4, Hsap\NFASC, Hsap\TNN, Hsap\LIFR, Hsap\OSMR, Hsap\COL7A1, Hsap\L1CAM, Hsap\CNTN2, Hsap\TNXB, Hsap\CHL1" " embryonic stage , embryonic stage | >=11-12 hr , embryonic stage | >=9 hr " " larval stage | third instar , embryonic stage | >=11-12 hr , oogenesis stage && adult stage | female , embryonic stage | >6 hr , embryonic stage | >=8 hr , embryonic stage | >=7 hr , embryonic stage " " epidermis &&of imaginal disc

, neuron &&of imaginal disc

, larval muscle system

, follicle cell

, neuron&&ofimaginal disc

, central nervous system | restricted

, embryonic peripheral nervous system | restricted

, embryonic/larval trachea

, embryonic/larval hindgut

, embryonic/larval salivary gland

" FBgn0010383 Cyp18a1 Cytochrome P450-18a1 http://flybase.org/reports/FBgn0010383 FBgn0015708 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 steroid hydroxylase activity ; GO:0008395 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype ecdysteroid catabolic process ; GO:0046344 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype prepupal development ; GO:0035210 | inferred from mutant phenotype pupation ; GO:0035074 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype" - "CG6816, cyp18, CT20826, CYP18A1-Dm, CYP18, 18a1, Eig17-1, P450, 181H6T, CytP450, P-450, ESTS:181H6T, Cyt-P450-17C, Cyp18, Cyp18a1, cyp18a1, Cyp18A1" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG6816 11-Aug-17 DroID_v2017_08 "Drer\cyp2k8, Drer\cyp2x12, Drer\cyp2v1, Drer\zgc:101048, Drer\cyp17a1, Drer\cyp2p6, Drer\cyp2y3, Drer\cyp2ad2, Drer\cyp2ad6, Drer\cyp2k31, Drer\cyp2k19, Drer\cyp2aa3, Drer\cyp2aa8, Drer\cyp2x9, Drer\cyp2j20, Drer\cyp2aa6, Drer\cyp1b1, Drer\cyp2aa12, Drer\cyp2aa4, Drer\cyp17a2, Drer\cyp1d1, Drer\cyp2k21, Drer\cyp2p8, Drer\cyp1a, Drer\cyp2n13, Drer\cyp2p10, Drer\cyp2u1, Drer\cyp21a2, Drer\cyp2aa1, Drer\cyp2aa9, Drer\cyp2k17, Drer\cyp1c1, Drer\si:zfos-411a11.2, Drer\cyp1c2, Drer\cyp2r1, Drer\cyp2x7, Drer\cyp2x10.2, Drer\cyp2ae1, Drer\cyp2k18, Drer\cyp2x8, Drer\cyp2p7, Drer\cyp2k6, Drer\si:dkey-286h2.7, Drer\cyp2k16, Drer\cyp2aa2, Drer\cyp2k20, Drer\cyp2ad3, Drer\cyp2p9, Drer\cyp2k22, Drer\LOC100148115, Drer\cyp2x6, Drer\cyp2aa11" - "Cele\cyp-14A4, Cele\cyp-33C12, Cele\cyp-35A2, Cele\cyp-35A4, Cele\cyp-33C3, Cele\cyp-33C9, Cele\cyp-33C2, Cele\cyp-34A2, Cele\cyp-33C4, Cele\cyp-34A6, Cele\cyp-33C1, Cele\cyp-33C11, Cele\cyp-35A1, Cele\cyp-34A7, Cele\daf-9, Cele\cyp-14A5, Cele\cyp-33C8, Cele\cyp-34A1, Cele\cyp-35C1, Cele\cyp-35B2, Cele\cyp-14A1, Cele\cyp-33E1, Cele\cyp-14A2, Cele\cyp-34A8, Cele\cyp-35B3, Cele\cyp-35D1, Cele\cyp-33C6, Cele\cyp-33D3, Cele\cyp-34A9, Cele\cyp-33D1, Cele\cyp-35A5, Cele\cyp-33E2, Cele\cyp-23A1, Cele\cyp-34A10, Cele\cyp-33C5, Cele\cyp-34A5, Cele\cyp-33A1, Cele\cyp-36A1, Cele\cyp-33E3, Cele\cyp-35B1, Cele\cyp-34A4, Cele\cyp-35A3, Cele\cyp-14A3, Cele\cyp-33B1, Cele\cyp-33C7" "Xtro\cyp17a1, Xtro\LOC100145323, Xtro\LOC100486127, Xtro\LOC100036663, Xtro\cyp2u1, Xtro\cyp2e1, Xtro\cyp2d6, Xtro\cyp2c18, Xtro\cyp21a2.1, Xtro\cyp2w1, Xtro\LOC100145541, Xtro\LOC100497460, Xtro\cyp2a6, Xtro\LOC548374, Xtro\MGC69353, Xtro\cyp1b1, Xtro\LOC100490015, Xtro\cyp2r1, Xtro\LOC100495359, Xtro\cyp2j2, Xtro\LOC619584, Xtro\MGC69416, Xtro\LOC100497184, Xtro\cyp2a13, Xtro\cyp1a1, Xtro\cyp1d1, Xtro\LOC100145084, Xtro\cyp2g1p, Xtro\LOC100145695, Xtro\cyp2b6, Xtro\cyp2c8.2, Xtro\MGC107969, Xtro\cyp2f2, Xtro\cyp2c8.1, Xtro\LOC100493194, Xtro\LOC100490476" "Mmus\Cyp2c67, Mmus\Cyp2c55, Mmus\Cyp2c39, Mmus\Cyp2d34, Mmus\Cyp2r1, Mmus\Cyp2b13, Mmus\Cyp2c38, Mmus\Cyp2j6, Mmus\Cyp2j9, Mmus\Cyp21a1, Mmus\Cyp2d10, Mmus\Cyp17a1, Mmus\Cyp2c66, Mmus\Cyp2b19, Mmus\Cyp2d22, Mmus\Cyp2c70, Mmus\Cyp1a2, Mmus\Cyp2c29, Mmus\Cyp1b1, Mmus\Cyp2d11, Mmus\Cyp2e1, Mmus\Cyp2f2, Mmus\Cyp2ab1, Mmus\Cyp2g1, Mmus\Cyp2c69, Mmus\Cyp2b10, Mmus\Cyp2a5, Mmus\Cyp2d12, Mmus\Cyp2c65, Mmus\Cyp2a12, Mmus\Cyp2j5, Mmus\Cyp2c50, Mmus\Cyp2w1, Mmus\Cyp2c40, Mmus\Cyp2j13, Mmus\Cyp2a4, Mmus\Cyp2t4, Mmus\Cyp1a1, Mmus\Cyp2c68, Mmus\Cyp2s1, Mmus\Cyp2b9, Mmus\Cyp2d9, Mmus\Cyp2a22, Mmus\Cyp2u1, Mmus\Cyp2c54, Mmus\Cyp2d26, Mmus\Cyp2j11, Mmus\Cyp2b23, Mmus\Cyp2d40, Mmus\Cyp2c37, Mmus\Cyp2c44, Mmus\Cyp2j12, Mmus\Cyp2j8" "Hsap\CYP1A2, Hsap\CYP2D6, Hsap\CYP2C18, Hsap\CYP2E1, Hsap\CYP2C8, Hsap\CYP2A13, Hsap\CYP2S1, Hsap\CYP2F1, Hsap\CYP2A6, Hsap\CYP2J2, Hsap\CYP21A2, Hsap\CYP2U1, Hsap\CYP2C9, Hsap\CYP2W1, Hsap\CYP1B1, Hsap\CYP17A1, Hsap\CYP1A1, Hsap\CYP2A7, Hsap\CYP2C19, Hsap\CYP2B6, Hsap\CYP2R1" "viable,fertile,lethal,developmental rate defective,melanotic mass phenotype,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "midgut | third instar larval stage,cuticle | third instar larval stage,metathoracic leg,adult head,embryonic dorsal epidermis,embryonic/first instar larval cuticle,embryonic head,embryonic/larval midgut primordium,denticle belt,leg | pupal stage,adult head | pupal stage" DRSC20235 I 1.04877799 1.78193124 -0.040245948 0.434405518 0.441191737 0.912267022 FBgn0032684 CG10178 - http://flybase.org/reports/FBgn0032684 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG10178 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG10178 11-Aug-17 DroID_v2017_08 "Drer\ugt5b3, Drer\ugt5g1, Drer\ugt5b2, Drer\ugt8, Drer\ugt5a2, Drer\ugt2a5, Drer\ugt1a5, Drer\ugt5c2, Drer\ugt2b5, Drer\ugt2a6, Drer\ugt1ab, Drer\ugt1a4, Drer\ugt5b4, Drer\ugt5g2, Drer\ugt1b1, Drer\ugt5a4, Drer\zgc:172315, Drer\ugt1b4, Drer\ugt5b1, Drer\ugt5a1, Drer\ugt5f1, Drer\ugt1b5, Drer\ugt2a2, Drer\ugt1b2, Drer\ugt2b3, Drer\ugt1a6, Drer\ugt5c3, Drer\ugt5e1, Drer\ugt1a1, Drer\ugt1a7, Drer\ugt5d1, Drer\ugt2b1, Drer\ugt1b3, Drer\ugt5a5, Drer\ugt5c1, Drer\ugt1b7, Drer\ugt5b6, Drer\ugt2b6, Drer\ugt1a2" Scer\ATG26 "Cele\ugt-58, Cele\ugt-49, Cele\ugt-55, Cele\ugt-29, Cele\C23G10.6, Cele\ugt-6, Cele\ugt-56, Cele\ugt-23, Cele\ugt-48, Cele\C03A7.12, Cele\ugt-51, Cele\ugt-46, Cele\ugt-31, Cele\ugt-40, Cele\ugt-7, Cele\ugt-12, Cele\ugt-42, Cele\ugt-24, Cele\ugt-61, Cele\ugt-28, Cele\ugt-41, Cele\ugt-36, Cele\ugt-19, Cele\K04A8.10, Cele\ugt-10, Cele\ugt-57, Cele\F54C1.1, Cele\ugt-1, Cele\ugt-5, Cele\ugt-50, Cele\ugt-59, Cele\ugt-38, Cele\H23N18.4, Cele\ugt-30, Cele\ugt-16, Cele\ugt-37, Cele\ugt-3, Cele\C55H1.1, Cele\ugt-17, Cele\ugt-39, Cele\ugt-21, Cele\ugt-4, Cele\ugt-15, Cele\ugt-22, Cele\ugt-8, Cele\ugt-44, Cele\ugt-18, Cele\ugt-52, Cele\ugt-43, Cele\ugt-33, Cele\ugt-9, Cele\F10D2.8, Cele\ugt-34, Cele\ugt-65, Cele\ugt-53, Cele\ugt-20, Cele\ugt-62, Cele\ugt-35, Cele\Y43D4A.2, Cele\ugt-45, Cele\ugt-13, Cele\ugt-54, Cele\ugt-25, Cele\ugt-47, Cele\ugt-27, Cele\ugt-2, Cele\C03A7.13, Cele\ugt-60, Cele\ugt-26, Cele\ugt-14, Cele\ugt-11, Cele\ugt-32" "Xtro\ugt2b4, Xtro\ugt3a2, Xtro\ugt1a6, Xtro\ugt2a1, Xtro\ugt8" "Mmus\Ugt1a5, Mmus\Ugt1a7c, Mmus\Ugt2b5, Mmus\Ugt8a, Mmus\Ugt1a1, Mmus\Ugt2b38, Mmus\Ugt1a2, Mmus\Ugt2a2, Mmus\Ugt2b36, Mmus\Ugt1a9, Mmus\Ugt1a6b, Mmus\Ugt3a2, Mmus\Ugt2a1, Mmus\Ugt2b34, Mmus\Ugt2b37, Mmus\Ugt3a1, Mmus\Ugt2a3, Mmus\Ugt1a10, Mmus\Ugt2b1, Mmus\Ugt2b35" "Hsap\UGT3A2, Hsap\UGT2B10, Hsap\UGT2B15, Hsap\UGT2A3, Hsap\UGT1A10, Hsap\UGT8, Hsap\UGT2A2, Hsap\UGT3A1, Hsap\UGT2B4, Hsap\UGT1A9, Hsap\UGT2B7, Hsap\UGT1A1, Hsap\UGT1A8, Hsap\UGT1A5, Hsap\UGT1A3, Hsap\UGT2B17, Hsap\UGT1A6, Hsap\UGT2B28, Hsap\UGT1A7, Hsap\UGT1A4, Hsap\UGT2B11" viable FBgn0266377 Pde8 Phosphodiesterase 8 http://flybase.org/reports/FBgn0266377 protein_coding_gene "3',5'-cyclic-nucleotide phosphodiesterase activity ; GO:0004114 | inferred from electronic annotation with InterPro:IPR002073 3',5'-cyclic-AMP phosphodiesterase activity ; GO:0004115 | inferred from sequence model" positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern cAMP metabolic process ; GO:0046058 | inferred from sequence model negative regulation of hydrogen peroxide-induced cell death ; GO:1903206 | inferred from mutant phenotype - "CG45019, PDE8, CG5411, Pde8, pde8, CG42241" "IPR000014:PAS domain, IPR002073:3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR003607:HD/PDEase domain, IPR023088:3'5'-cyclic nucleotide phosphodiesterase" CG45019 11-Aug-17 DroID_v2017_08 "Drer\pde8b, Drer\pde9al, Drer\pde8a, Drer\pde9a" Scer\PDE2 Cele\pde-6 "Xtro\pde8a, Xtro\pde8b" "Mmus\Pde8a, Mmus\Pde9a, Mmus\Pde8b" "Hsap\PDE8B, Hsap\PDE9A, Hsap\PDE8A" FBgn0038774 CG5023 - http://flybase.org/reports/FBgn0038774 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR001997 actin binding ; GO:0003779 | inferred from sequence or structural similarity actomyosin structure organization ; GO:0031032 | inferred from electronic annotation with InterPro:IPR001997 - CG5023 "IPR000557:Calponin repeat, IPR001715:Calponin homology domain, IPR001997:Calponin/LIMCH1, IPR003096:Smooth muscle protein/calponin" CG5023 11-Aug-17 DroID_v2017_08 "Drer\cnn3b, Drer\tagln3b, Drer\cnn3a, Drer\cnn1a, Drer\cnn2, Drer\iqgap2, Drer\cnn1b, Drer\tagln3a, Drer\tagln, Drer\tagln2" "Scer\SCP1, Scer\IQG1" "Cele\pes-7, Cele\cpn-3, Cele\cpn-2, Cele\cpn-1" "Xtro\cnn3, Xtro\cnn1, Xtro\tagln2, Xtro\tagln, Xtro\cnn2" "Mmus\Tagln2, Mmus\Iqgap3, Mmus\Cnn3, Mmus\Cnn2, Mmus\Tagln3, Mmus\Tagln, Mmus\Cnn1, Mmus\Iqgap1" "Hsap\TAGLN2, Hsap\IQGAP3, Hsap\TAGLN3, Hsap\CNN1, Hsap\IQGAP1, Hsap\CNN3, Hsap\TAGLN, Hsap\CNN2" viable DRSC15697 I 1.674850437 0.308748245 1.470077772 -0.794171845 -0.92061959 -0.53949205 FBgn0035978 UGP UGP http://flybase.org/reports/FBgn0035978 protein_coding_gene UTP:glucose-1-phosphate uridylyltransferase activity ; GO:0003983 | inferred from sequence or structural similarity with SGD:S000001518 UTP:glucose-1-phosphate uridylyltransferase activity ; GO:0003983 | inferred from biological aspect of ancestor with PANTHER:PTN002460644 glycogen metabolic process ; GO:0005977 | inferred from biological aspect of ancestor with PANTHER:PTN002460644 response to hyperoxia ; GO:0055093 | inferred from mutant phenotype UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with SGD:S000001518 UDP-glucose metabolic process ; GO:0006011 | inferred from biological aspect of ancestor with PANTHER:PTN002460644 cytosol ; GO:0005829 | inferred from direct assay "UGPase, CG4347, UDPGPP, UGP" "IPR002618:UDPGP family, IPR016267:UTP--glucose-1-phosphate uridylyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases" CG4347 11-Aug-17 DroID_v2017_08 "Drer\ugp2a, Drer\ugp2b" "Scer\UGP1, Scer\YHL012W" "Cele\D1005.2, Cele\K08E3.5" Xtro\ugp2 Mmus\Ugp2 Hsap\UGP2 viable FBgn0030672 CG9281 - http://flybase.org/reports/FBgn0030672 protein_coding_gene "ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871" - - "BEST:LD38280, CG9281" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR032781:ABC-transporter extension domain" CG9281 11-Aug-17 DroID_v2017_08 "Drer\abcf3, Drer\abcf2b, Drer\abcf2a, Drer\abcf1" "Scer\YEF3, Scer\HEF3, Scer\ARB1, Scer\NEW1" "Cele\abcf-2, Cele\abcf-1" "Xtro\abcf1, Xtro\abcf3" "Mmus\Abcf3, Mmus\Abcf2, Mmus\Abcf1" "Hsap\ABCF1, Hsap\ABCF3, Hsap\ABCF2" "viable,fertile" FBgn0053871 His4:CG33871 His4:CG33871 http://flybase.org/reports/FBgn0053871 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33871, His4:CG33871" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33871 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-368j24.1, Drer\LOC100329358, Drer\zgc:163040, Drer\si:ch211-113a14.26, Drer\si:dkey-108k21.19, Drer\si:ch211-113a14.17, Drer\si:ch73-36p18.4, Drer\hist1h4l, Drer\zgc:153409, Drer\si:ch211-113a14.6, Drer\si:dkey-108k21.12, Drer\LOC562770, Drer\LOC100331412, Drer\zgc:154164, Drer\si:dkey-261m9.17, Drer\LOC100150038, Drer\LOC794549, Drer\zgc:194989, Drer\si:ch73-368j24.14, Drer\si:dkey-261m9.18, Drer\si:ch73-36p18.3, Drer\si:dkey-108k21.28, Drer\si:dkey-23a13.7, Drer\LOC570405" "Scer\HHF1, Scer\HHF2" "Cele\his-1, Cele\his-38, Cele\his-64, Cele\his-5, Cele\his-50, Cele\his-60, Cele\his-67, Cele\his-37, Cele\his-31, Cele\his-18, Cele\his-56, Cele\his-28, Cele\his-10, Cele\his-46, Cele\his-26, Cele\his-14" "Xtro\hist1h4k, Xtro\LOC100496758, Xtro\LOC100485271, Xtro\hist1h4a, Xtro\LOC100493041, Xtro\hist1h4c" "Mmus\Hist1h4n, Mmus\Hist1h4f, Mmus\Hist1h4k, Mmus\Hist1h4a, Mmus\Hist2h4, Mmus\Hist1h4d, Mmus\Hist1h4i, Mmus\Hist1h4c, Mmus\Hist1h4m, Mmus\Hist1h4j, Mmus\Hist1h4h, Mmus\Hist4h4, Mmus\Hist1h4b" "Hsap\HIST1H4I, Hsap\HIST1H4L, Hsap\HIST1H4D, Hsap\HIST1H4J, Hsap\HIST2H4B, Hsap\HIST1H4K, Hsap\HIST1H4F, Hsap\HIST1H4C, Hsap\HIST1H4E, Hsap\HIST4H4, Hsap\HIST1H4B, Hsap\HIST2H4A, Hsap\HIST1H4G, Hsap\HIST1H4A, Hsap\HIST1H4H" FBgn0053883 His4:CG33883 His4:CG33883 http://flybase.org/reports/FBgn0053883 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33883, His4:CG33883" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33883 11-Aug-17 DroID_v2017_08 "Drer\zgc:153409, Drer\LOC100331412, Drer\si:ch73-36p18.4, Drer\si:ch73-368j24.14, Drer\zgc:163040, Drer\LOC570405, Drer\si:dkey-108k21.12, Drer\zgc:154164, Drer\LOC100150038, Drer\si:ch73-368j24.1, Drer\LOC100329358, Drer\LOC562770, Drer\LOC794549, Drer\si:ch73-36p18.3, Drer\si:ch211-113a14.26, Drer\si:dkey-108k21.28, Drer\si:dkey-261m9.18, Drer\si:ch211-113a14.6, Drer\si:dkey-261m9.17, Drer\zgc:194989, Drer\hist1h4l, Drer\si:ch211-113a14.17, Drer\si:dkey-108k21.19, Drer\si:dkey-23a13.7" "Scer\HHF1, Scer\HHF2" "Cele\his-60, Cele\his-64, Cele\his-26, Cele\his-67, Cele\his-38, Cele\his-1, Cele\his-37, Cele\his-14, Cele\his-18, Cele\his-5, Cele\his-10, Cele\his-31, Cele\his-46, Cele\his-50, Cele\his-28, Cele\his-56" "Xtro\hist1h4k, Xtro\hist1h4c, Xtro\LOC101732638, Xtro\LOC100493041" "Mmus\Hist1h4m, Mmus\Hist1h4k, Mmus\Hist1h4i, Mmus\Hist4h4, Mmus\Hist2h4, Mmus\Hist1h4n, Mmus\Hist1h4b, Mmus\Hist1h4d, Mmus\Hist1h4c, Mmus\Hist1h4a, Mmus\Hist1h4f, Mmus\Hist1h4h, Mmus\Hist1h4j" "Hsap\HIST1H4C, Hsap\HIST1H4H, Hsap\HIST1H4L, Hsap\HIST1H4I, Hsap\HIST1H4A, Hsap\HIST1H4B, Hsap\HIST1H4G, Hsap\HIST1H4K, Hsap\HIST1H4E, Hsap\HIST2H4A, Hsap\HIST4H4, Hsap\HIST1H4J, Hsap\HIST1H4D, Hsap\HIST1H4F, Hsap\HIST2H4B" FBgn0015402 ksr kinase suppressor of ras http://flybase.org/reports/FBgn0015402 FBgn0011387 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 protein kinase activity ; GO:0004672 | inferred from biological aspect of ancestor with PANTHER:PTN000584058" "signal transduction ; GO:0007165 | inferred from direct assay anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement torso signaling pathway ; GO:0008293 | non-traceable author statement Ras protein signal transduction ; GO:0007265 | inferred from genetic interaction with Ras85D positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D protein phosphorylation ; GO:0006468 | non-traceable author statement tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001907285 "ksr, KSR, Ksr, CG2899, KSR-1, EK3-1, l(3)j5E2, dKsr, Ksr-1, SR3-1, EC3-1" "IPR025561:Kinase suppressor of RAS, SAM-like domain, IPR000719:Protein kinase domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG2899 11-Aug-17 DroID_v2017_08 "Drer\ksr1b, Drer\ksr2, Drer\braf, Drer\raf1b, Drer\ksr1a, Drer\araf" - "Cele\ZK622.1, Cele\ksr-2, Cele\ksr-1" "Xtro\braf, Xtro\raf1, Xtro\araf, Xtro\ksr1" "Mmus\Ksr1, Mmus\Raf1, Mmus\Braf, Mmus\Araf, Mmus\Ksr2" "Hsap\RAF1, Hsap\KSR2, Hsap\ARAF, Hsap\KSR1, Hsap\BRAF" "lethal,recessive,visible,dominant,germline clone,non-rescuable maternal effect,terminal phenotype,maternal effect,partially lethal - majority die" "wing,abdominal segment 8 & cephalopharyngeal skeleton | germ-line clone,abdominal segment 9 & cephalopharyngeal skeleton | germ-line clone,abdominal segment 10 & cephalopharyngeal skeleton | germ-line clone,abdominal segment 11 & cephalopharyngeal skeleton | germ-line clone,terminalia,germline clone,dorsal air sac primordium,somatic clone,A1-7 ventral acute muscle 2,precursor,eye photoreceptor cell,eye,photoreceptor cell,ommatidium,embryo,maternal effect,mesothoracic tergum" DRSC12379 IEK -1.488192508 -7.044356403 -2.511449496 -8.299114981 -4.329933676 -5.038492496 FBgn0053865 His2A:CG33865 His2A:CG33865 http://flybase.org/reports/FBgn0053865 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33865, His2A:CG33865" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33865 11-Aug-17 DroID_v2017_08 "Drer\zgc:173652, Drer\si:ch211-113a14.16, Drer\si:dkey-261m9.11, Drer\si:dkey-23a13.7, Drer\si:dkey-261m9.18, Drer\si:ch211-113a14.11, Drer\zgc:110434, Drer\si:ch1073-159d7.9, Drer\h2afx, Drer\si:dkey-261m9.15, Drer\si:dkey-108k21.19, Drer\si:dkey-23a13.20, Drer\zgc:165551, Drer\si:ch73-368j24.13, Drer\si:ch211-113a14.26, Drer\si:ch73-36p18.5, Drer\si:ch1073-153i20.5, Drer\h2afy2, Drer\zgc:101846, Drer\zgc:195633, Drer\fbxl6, Drer\LOC100148591, Drer\si:ch211-113a14.7, Drer\si:ch73-368j24.15, Drer\si:dkey-108k21.26, Drer\LOC100332229, Drer\si:ch1073-159d7.10, Drer\si:dkey-261m9.7, Drer\si:dkey-23a13.14, Drer\zgc:154164, Drer\LOC100334934, Drer\si:ch73-368j24.14, Drer\zgc:114037, Drer\si:dkey-108k21.15, Drer\si:ch211-113a14.19, Drer\LOC570115, Drer\si:ch1073-159d7.11" "Scer\HTA1, Scer\HTA2" "Cele\his-12, Cele\his-53, Cele\his-19, Cele\htas-1, Cele\his-65, Cele\his-21, Cele\his-43, Cele\his-16, Cele\his-68, Cele\his-35, Cele\his-57, Cele\his-30, Cele\his-61, Cele\his-51, Cele\his-7, Cele\his-3, Cele\his-33, Cele\his-47" "Xtro\hist1h2am, Xtro\hist1h2ah, Xtro\h2afj, Xtro\hist1h2aa, Xtro\h2afx, Xtro\LOC100486672, Xtro\h2afy2, Xtro\hist1h2aj, Xtro\h2afy, Xtro\hist1h2ad" "Mmus\Hist1h2ap, Mmus\Hist1h2an, Mmus\Gm14920, Mmus\H2afx, Mmus\H2al1j, Mmus\Hist1h2ak, Mmus\Hist1h2ah, Mmus\Hist2h2ac, Mmus\Hist2h2aa1, Mmus\Hist3h2a, Mmus\H2afb1, Mmus\H2afb3, Mmus\Hist2h2ab, Mmus\Hist2h2aa2, Mmus\Hist1h2ag, Mmus\H2afy, Mmus\H2al2b, Mmus\Hist1h2aa, Mmus\Hist1h2af, Mmus\H2al1n, Mmus\Hist1h2ao, Mmus\H2afb2, Mmus\H2afy2, Mmus\Hist1h2ae, Mmus\H2afj, Mmus\Hist1h2ai, Mmus\Hist1h2ac, Mmus\H2al2c, Mmus\Hist1h2ab, Mmus\Hist1h2ad" "Hsap\HIST1H2AK, Hsap\HIST1H2AH, Hsap\HIST1H2AG, Hsap\H2AFB2, Hsap\H2AFJ, Hsap\HIST1H2AA, Hsap\HIST1H2AD, Hsap\HIST2H2AA3, Hsap\HIST1H2AL, Hsap\HIST2H2AB, Hsap\HIST2H2AC, Hsap\HIST1H2AJ, Hsap\H2AFB3, Hsap\HIST3H2A, Hsap\H2AFB1, Hsap\H2AFY, Hsap\HIST2H2AA4, Hsap\H2AFY2, Hsap\H2AFX, Hsap\HIST1H2AB, Hsap\HIST1H2AC, Hsap\HIST1H2AE, Hsap\HIST1H2AI, Hsap\HIST1H2AM" FBgn0260945 Atg1 Autophagy-related 1 http://flybase.org/reports/FBgn0260945 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein binding ; GO:0005515 | inferred from physical interaction with Atg101 protein kinase activity ; GO:0004672 | inferred from direct assay protein kinase activity ; GO:0004672 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from mutant phenotype protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype ubiquitin-like protein binding ; GO:0032182 | inferred from physical interaction with Atg8a" positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype larval midgut histolysis ; GO:0035069 | inferred from mutant phenotype positive regulation of nurse cell apoptotic process ; GO:0045850 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from direct assay inferred from mutant phenotype autophagy ; GO:0006914 | inferred from genetic interaction with Atg17 synapse organization ; GO:0050808 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from genetic interaction with Dronc response to oxidative stress ; GO:0006979 | inferred from genetic interaction with puc axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype glycophagy ; GO:0061723 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype endocytosis ; GO:0006897 | NOT inferred from mutant phenotype macroautophagy ; GO:0016236 | inferred from mutant phenotype modulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of cell growth ; GO:0001558 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype positive regulation of glycogen catabolic process ; GO:0045819 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement negative regulation of phosphatidylinositol 3-kinase signaling ; GO:0014067 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype ATG1/ULK1 kinase complex ; GO:1990316 | inferred from direct assay "Atg1, atg1, ULK1, unc51, unc-51, ATG1, CG10967, l(3)00305, UNC 51-like, anon-WO0118547.287, Unc-51, DK-4, dATG1, DmATG1, dAtg1, Unc51" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017184:Serine/threonine-protein kinase Unc-51, IPR017441:Protein kinase, ATP binding site, IPR015943:WD40/YVTN repeat-like-containing domain, IPR022708:Serine/threonine-protein kinase, C-terminal" CG10967 11-Aug-17 DroID_v2017_08 "Drer\pdik1l, Drer\si:ch211-63o20.7, Drer\ulk1b, Drer\ulk2, Drer\stk35, Drer\stk35l, Drer\ulk1a" Scer\ATG1 Cele\unc-51 "Xtro\ulk3, Xtro\ulk1, Xtro\stk35, Xtro\pdik1l" "Mmus\Ulk1, Mmus\Ulk2, Mmus\Stk35, Mmus\Ulk3, Mmus\Pdik1l" "Hsap\ULK2, Hsap\ULK3, Hsap\PDIK1L, Hsap\STK35, Hsap\ULK1" FBgn0026314 Ugt35b UDP-glycosyltransferase 35b http://flybase.org/reports/FBgn0026314 "FBgn0015836, FBgn0040258" protein_coding_gene UDP-glycosyltransferase activity ; GO:0008194 | inferred from sequence or structural similarity with UniProtKB:P18569 glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with UniProtKB:P18569 integral component of membrane ; GO:0016021 | inferred from sequence model intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "ugt35b, AC 006491B, DmeUgt35b, Ugt86Db, UDPGT2, CG6649, Ugt35b, Ugt35B, UGT35b, Ugt-35b" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG6649 11-Aug-17 DroID_v2017_08 "Drer\ugt5b2, Drer\ugt5b1, Drer\ugt1ab, Drer\zgc:172315, Drer\ugt2b1, Drer\ugt5a4, Drer\ugt5b4, Drer\ugt5g2, Drer\ugt5a5, Drer\ugt5g1, Drer\ugt2a5, Drer\ugt1b2, Drer\ugt2a2, Drer\ugt5f1, Drer\ugt2a4, Drer\ugt5d1, Drer\ugt2a6, Drer\ugt5a2, Drer\ugt2a3, Drer\ugt2b5, Drer\ugt5e1, Drer\ugt5c1, Drer\ugt2b3, Drer\ugt1b5, Drer\ugt2b6, Drer\ugt1b7, Drer\ugt5b3, Drer\ugt8, Drer\ugt1b4, Drer\ugt2a1, Drer\ugt5a1, Drer\ugt5b6, Drer\ugt5c3, Drer\ugt1b3, Drer\ugt5c2" Scer\ATG26 "Cele\ugt-2, Cele\ugt-58, Cele\F54C1.1, Cele\ugt-50, Cele\ugt-16, Cele\C03A7.13, Cele\ugt-53, Cele\ugt-65, Cele\ugt-43, Cele\ugt-59, Cele\ugt-1, Cele\H23N18.4, Cele\ugt-13, Cele\ugt-57, Cele\ugt-19, Cele\Y43D4A.2, Cele\ugt-8, Cele\ugt-30, Cele\ugt-14, Cele\C03A7.12, Cele\ugt-4, Cele\ugt-25, Cele\ugt-32, Cele\K04A8.10, Cele\ugt-60, Cele\ugt-51, Cele\ugt-24, Cele\ugt-44, Cele\C23G10.6, Cele\ugt-47, Cele\F10D2.8, Cele\ugt-28, Cele\ugt-54, Cele\ugt-3, Cele\ugt-17, Cele\ugt-52, Cele\ugt-18, Cele\ugt-56, Cele\ugt-45, Cele\ugt-5, Cele\ugt-10, Cele\ugt-15, Cele\ugt-11, Cele\ugt-46, Cele\C55H1.1, Cele\ugt-12, Cele\ugt-20, Cele\ugt-9, Cele\ugt-42, Cele\ugt-48, Cele\ugt-55, Cele\ugt-37, Cele\ugt-62, Cele\ugt-38, Cele\ugt-41, Cele\ugt-36, Cele\ugt-31, Cele\ugt-22, Cele\ugt-40, Cele\ugt-29, Cele\ugt-26, Cele\ugt-6, Cele\ugt-49, Cele\ugt-7, Cele\ugt-35, Cele\ugt-27, Cele\ugt-61, Cele\ugt-21, Cele\ugt-39, Cele\ugt-34, Cele\ugt-33, Cele\ugt-23" "Xtro\ugt1a6, Xtro\ugt2b4, Xtro\ugt8, Xtro\ugt2a1, Xtro\ugt3a2" "Mmus\Ugt1a7c, Mmus\Ugt1a1, Mmus\Ugt2b1, Mmus\Ugt1a10, Mmus\Ugt2b34, Mmus\Ugt1a2, Mmus\Ugt2b37, Mmus\Ugt3a2, Mmus\Ugt3a1, Mmus\Ugt2a3, Mmus\Ugt2b36, Mmus\Ugt8a, Mmus\Ugt2a2, Mmus\Ugt2a1, Mmus\Ugt2b5, Mmus\Ugt2b35, Mmus\Ugt1a5, Mmus\Ugt1a9, Mmus\Ugt1a6b, Mmus\Ugt2b38" "Hsap\UGT1A9, Hsap\UGT1A8, Hsap\UGT1A10, Hsap\UGT2B11, Hsap\UGT2A3, Hsap\UGT8, Hsap\UGT2A2, Hsap\UGT1A5, Hsap\UGT2B7, Hsap\UGT2B4, Hsap\UGT1A4, Hsap\UGT2B10, Hsap\UGT1A1, Hsap\UGT2B28, Hsap\UGT3A1, Hsap\UGT2B17, Hsap\UGT1A3, Hsap\UGT1A6, Hsap\UGT3A2, Hsap\UGT1A7, Hsap\UGT2B15" adult stage " antennal segment 3

, adult head

, leg

" viable FBgn0030276 Dlic Dynein light intermediate chain http://flybase.org/reports/FBgn0030276 protein_coding_gene microtubule motor activity ; GO:0003777 | inferred from electronic annotation with InterPro:IPR008467 dynein heavy chain binding ; GO:0045504 | inferred from sequence or structural similarity with UniProtKB:Q9Y6G9 dynein heavy chain binding ; GO:0045504 | inferred from biological aspect of ancestor with PANTHER:PTN000293992 microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from direct assay microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity mRNA transport ; GO:0051028 | inferred from direct assay axonogenesis ; GO:0007409 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype centrosome ; GO:0005813 | colocalizes_with inferred from direct assay dynein complex ; GO:0030286 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from physical interaction with Dhc64C cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic dynein complex ; GO:0005868 | inferred from direct assay nuclear envelope ; GO:0005635 | colocalizes_with inferred from direct assay "CG1938, DLIC2, l(1)G0065, l(1)G0190, dlic, Dlic, dlic2, Dlic2, DLIC, D-LIC" "IPR008467:Dynein 1 light intermediate chain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022780:Dynein family light intermediate chain" CG1938 11-Aug-17 DroID_v2017_08 "Drer\dync1li1, Drer\dync1li2, Drer\dync2li1" - "Cele\dli-1, Cele\xbx-1" "Xtro\LOC100498570, Xtro\dync1li1, Xtro\dync1li2" "Mmus\Dync1li1, Mmus\Dync2li1, Mmus\Dync1li2" "Hsap\DYNC1LI2, Hsap\DYNC1LI1, Hsap\DYNC2LI1" "neuroanatomy defective,somatic clone,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" "dendrite & abdominal dorsal multidendritic neuron ddaC | somatic clone,axon & abdominal dorsal multidendritic neuron ddaC | somatic clone,Golgi apparatus & abdominal dorsal multidendritic neuron ddaC | somatic clone,egg chamber,germline clone,oocyte,nurse cell ring canal,class IV dendritic arborizing neuron,somatic clone,terminal tracheal cell" FBgn0261953 TfAP-2 Transcription factor AP-2 http://flybase.org/reports/FBgn0261953 protein_coding_gene "RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000087637 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000087637 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000087637 adult feeding behavior ; GO:0008343 | inferred from mutant phenotype imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from genetic interaction with twz male courtship behavior ; GO:0008049 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay proboscis development ; GO:0048728 | inferred from mutant phenotype imaginal disc-derived male genitalia development ; GO:0007485 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG7807, dAP-2, TfAP-2, dAP-2alpha, DAP-2, AP-2alpha, l(3)1215, AP-2, dTfap2" "IPR004979:Transcription factor AP-2, IPR013854:Transcription factor AP-2, C-terminal" CG7807 11-Aug-17 DroID_v2017_08 "Drer\tfap2b, Drer\tfap2a, Drer\tfap2d, Drer\tfap2e, Drer\tfap2c" - "Cele\aptf-4, Cele\aptf-2, Cele\aptf-1, Cele\aptf-3" "Xtro\tfap2c, Xtro\tfap2a, Xtro\tfap2e, Xtro\tfap2b" "Mmus\Tfap2d, Mmus\Tfap2a, Mmus\Tfap2c, Mmus\Tfap2b, Mmus\Tfap2e" "Hsap\TFAP2C, Hsap\TFAP2D, Hsap\TFAP2E, Hsap\TFAP2B, Hsap\TFAP2A" " larval stage | third instar , embryonic stage | stage 9-13 , embryonic stage | stage 12 , embryonic stage | stage 14 , embryonic stage | stage 14--larval stage , embryonic stage | stage 10-13 " " ventral nerve cord

, ventral thoracic disc

, procephalic neurogenic region | restricted

, eye-antennal disc | restricted

, embryonic protocerebrum

, brain | restricted

, larval optic lobe

, embryonic protocerebral neuromere

, procephalic neuroblast

" FBgn0005536 Mbs Myosin binding subunit http://flybase.org/reports/FBgn0005536 "FBgn0010817, FBgn0011346, FBgn0011399, FBgn0028052, FBgn0028127, FBgn0036561, FBgn0036562, FBgn0052156, FBgn0061116, FBgn0062264" protein_coding_gene protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR031775 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype regulation of compound eye photoreceptor development ; GO:0045314 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype germline ring canal formation ; GO:0030725 | inferred from mutant phenotype imaginal disc morphogenesis ; GO:0007560 | inferred from mutant phenotype epidermis development ; GO:0008544 | inferred from mutant phenotype dorsal closure ; GO:0007391 | non-traceable author statement regulation of locomotor rhythm ; GO:1904059 | inferred from mutant phenotype apical cortex ; GO:0045179 | colocalizes_with inferred from direct assay apical junction complex ; GO:0043296 | colocalizes_with inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "MBS, DMBS, l(3)72Dd, DMYPT, DMbs, CG5891, l(3)03802, 0573/06, 0953/04, l(3)S095304, l(3)S005331b, l(3)S057306, l(3)S057306b, l(3)j7A1, l(3)j3B4, Mypt, CG5600, CG32156, Mbs, mbs" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR031775:cGMP-dependent protein kinase, interacting domain" CG32156 11-Aug-17 DroID_v2017_08 "Drer\ppp1r27a, Drer\zmp:0000001167, Drer\nrarpa, Drer\ppp1r16a, Drer\ppp1r16b, Drer\ppp1r12a, Drer\nrarpb, Drer\LOC101885790, Drer\ppp1r12c" Scer\AVO2 Cele\mel-11 "Xtro\ppp1r27, Xtro\ppp1r12b, Xtro\ppp1r16a, Xtro\ppp1r16b, Xtro\ppp1r12a, Xtro\nrarp, Xtro\ppp1r12c" "Mmus\Nrarp, Mmus\Ppp1r12b, Mmus\Ppp1r27, Mmus\Ppp1r12c, Mmus\Ppp1r16b, Mmus\Ppp1r12a, Mmus\Ppp1r16a" "Hsap\PPP1R12C, Hsap\PPP1R27, Hsap\PPP1R16B, Hsap\PPP1R16A, Hsap\PPP1R12B, Hsap\NRARP, Hsap\PPP1R12A" "neuroanatomy defective,somatic clone,lethal,recessive,germline clone,maternal effect,polyphasic,female sterile,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,fertile,viable,visible,cell polarity defective,lethal - all die before end of pupal stage,some die during pupal stage,developmental rate defective,axis specification defective" "axon | somatic clone | third instar larval stage,embryonic/first instar larval cuticle,embryonic leading edge cell,egg,germline clone,nurse cell ring canal,ovariole,ring canal,nurse cell,centriole | germline clone,wing disc,somatic clone,wing,dorsal,dorsal hair,eye disc,oocyte,morphogenetic furrow,germline cyst,imaginal disc,wing hair,adult abdomen,embryonic/larval epidermis,anterior embryonic/larval midgut | embryonic stage 16,embryonic proventriculus | embryonic stage 16,anterior embryonic/larval midgut | embryonic stage 15,embryonic proventriculus | embryonic stage 15,anterior embryonic/larval midgut | embryonic stage 17,embryonic proventriculus | embryonic stage 17,eye" FBgn0035414 CG14965 - http://flybase.org/reports/FBgn0035414 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612 - - "CG14965, dmLD47616p, ORF1, 63BC-T3, anon-63BC-T3" "IPR006612:Zinc finger, C2CH-type" CG14965 11-Aug-17 DroID_v2017_08 "Drer\zgc:158320, Drer\si:ch73-382f3.1, Drer\zgc:113364" - - - "Mmus\Thap3, Mmus\Thap7" "Hsap\THAP3, Hsap\THAP5, Hsap\THAP8, Hsap\THAP10, Hsap\THAP7" viable FBgn0263896 l(3)E47 - http://flybase.org/reports/FBgn0263896 gene - - - l(3)E47 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0053875 His4:CG33875 His4:CG33875 http://flybase.org/reports/FBgn0053875 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33875, His4:CG33875" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33875 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-23a13.7, Drer\LOC100329358, Drer\si:dkey-261m9.17, Drer\LOC100150038, Drer\LOC562770, Drer\si:dkey-261m9.18, Drer\si:ch73-368j24.1, Drer\LOC100331412, Drer\hist1h4l, Drer\si:ch73-36p18.4, Drer\si:ch211-113a14.17, Drer\zgc:153409, Drer\LOC570405, Drer\si:ch73-368j24.14, Drer\zgc:194989, Drer\si:ch211-113a14.6, Drer\zgc:163040, Drer\si:ch211-113a14.26, Drer\LOC794549, Drer\si:dkey-108k21.19, Drer\si:dkey-108k21.28, Drer\si:dkey-108k21.12, Drer\zgc:154164, Drer\si:ch73-36p18.3" "Scer\HHF1, Scer\HHF2" "Cele\his-56, Cele\his-18, Cele\his-60, Cele\his-26, Cele\his-37, Cele\his-46, Cele\his-50, Cele\his-38, Cele\his-10, Cele\his-28, Cele\his-5, Cele\his-1, Cele\his-67, Cele\his-14, Cele\his-31, Cele\his-64" "Xtro\LOC100493041, Xtro\LOC100488032, Xtro\hist1h4k, Xtro\hist1h4c" "Mmus\Hist1h4i, Mmus\Hist1h4d, Mmus\Hist1h4f, Mmus\Hist1h4h, Mmus\Hist2h4, Mmus\Hist1h4m, Mmus\Hist1h4n, Mmus\Hist1h4b, Mmus\Hist1h4k, Mmus\Hist1h4a, Mmus\Hist1h4j, Mmus\Hist1h4c, Mmus\Hist4h4" "Hsap\HIST2H4B, Hsap\HIST1H4B, Hsap\HIST1H4L, Hsap\HIST1H4F, Hsap\HIST1H4C, Hsap\HIST1H4E, Hsap\HIST1H4D, Hsap\HIST1H4H, Hsap\HIST1H4I, Hsap\HIST2H4A, Hsap\HIST1H4A, Hsap\HIST1H4G, Hsap\HIST1H4K, Hsap\HIST1H4J, Hsap\HIST4H4" FBgn0000042 Act5C Actin 5C http://flybase.org/reports/FBgn0000042 "FBgn0025223, FBgn0026673, FBgn0026683, FBgn0026712, FBgn0027215, FBgn0027255, FBgn0027284, FBgn0027327, FBgn0028278, FBgn0040144, FBgn0040204" protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity phagocytosis ; GO:0006909 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred by curator from GO:0031011 cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity sperm individualization ; GO:0007291 | inferred from expression pattern inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype tube formation ; GO:0035148 | inferred from genetic interaction with eys inferred from genetic interaction with prom mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay Ino80 complex ; GO:0031011 | inferred from direct assay actin filament ; GO:0005884 | inferred from sequence or structural similarity "Actin, CG4027, Actin/BAP47, actin, BAP47, T11, A, beta-actin/Bap47, Bap47, act5C, cyt5C, l(1)G0009, l(1)G0079, l(1)G0117, M32055, act 5C, Ac5C, l(1)G0010, l(1)G0486, l(1)G0025, l(1)G0177, l(1)G0245, l(1)G0330, l(1)G0420, anon-EST:fe2D2, Act5C, Act, Actin5C, actin5C, Act5c, Act-5C, beta-actin, act, ACT5C, Act5, ACT1_DROME, A4V404_DROME, chrX:5748184..5748304, ACT, ArpA" "IPR020902:Actin/actin-like conserved site, IPR004000:Actin family, IPR004001:Actin, conserved site" CG4027 11-Aug-17 DroID_v2017_08 "Drer\acta1a, Drer\actb1, Drer\si:ch211-241j12.3, Drer\si:ch73-187m15.4, Drer\actc1a, Drer\zgc:86725, Drer\actr1, Drer\acta1b, Drer\ankrd52b, Drer\acta2, Drer\zgc:86709, Drer\actr10, Drer\actc1b, Drer\actb2" "Scer\ARP9, Scer\ARP1, Scer\ACT1" "Cele\act-3, Cele\act-2, Cele\arp-1, Cele\act-5, Cele\act-4, Cele\act-1" "Xtro\actb, Xtro\actg1, Xtro\acta1, Xtro\actc1, Xtro\act3, Xtro\actr10, Xtro\ankrd52, Xtro\actr1a, Xtro\acta2" "Mmus\Actb, Mmus\Actr10, Mmus\Actrt2, Mmus\Actl7b, Mmus\Actr1b, Mmus\Actg1, Mmus\Actg2, Mmus\Actl11, Mmus\Acta2, Mmus\Actl9, Mmus\Actc1, Mmus\Actl7a, Mmus\Actl10, Mmus\Actrt1, Mmus\Actrt3, Mmus\Acta1, Mmus\Actr1a, Mmus\Actbl2" "Hsap\POTEI, Hsap\ACTR1A, Hsap\POTEB2, Hsap\ACTG1, Hsap\ACTL10, Hsap\ACTL8, Hsap\ACTRT1, Hsap\POTED, Hsap\ACTRT3, Hsap\ACTB, Hsap\POTEB, Hsap\ACTL7A, Hsap\ACTL7B, Hsap\ACTR1B, Hsap\POTEJ, Hsap\POTEE, Hsap\POTEH, Hsap\ACTA2, Hsap\POTEF, Hsap\POTEA, Hsap\ACTA1, Hsap\ACTG2, Hsap\ACTRT2, Hsap\ACTBL2, Hsap\ACTC1, Hsap\ACTL9, Hsap\POTEC, Hsap\POTEG, Hsap\ACTR10" " embryonic stage , embryonic stage | early " " embryonic central nervous system

, ventral nerve cord

,

ubiquitous , posterior embryonic/larval midgut

, subesophageal ganglion

, supraesophageal ganglion

, anterior embryonic/larval midgut

" "lethal - all die before end of larval stage,recessive,some die during larval stage,viable,fertile,behavior defective,lethal,partially lethal - majority die,visible,somatic clone,mitotic cell cycle defective" "head bristle,macrochaeta,mushroom body alpha-lobe,adult mushroom body alpha'-lobe,arista,trichome,eye,anterior crossvein,somatic clone,ectopic,germline cyst,border follicle cell,border follicle cell & filopodium,trichogen cell" DRSC17723 I -1.742969601 -2.287417467 0.00295251 -0.815609835 1.339159869 1.195704438 FBgn0261014 TER94 TER94 http://flybase.org/reports/FBgn0261014 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR005938 protein binding ; GO:0005515 | inferred from physical interaction with papi protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VBP9" muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype regulation of neuron apoptotic process ; GO:0043523 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype lysosome organization ; GO:0007040 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from mutant phenotype cellular response to virus ; GO:0098586 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from genetic interaction with tud inferred from genetic interaction with vas endoplasmic reticulum membrane fusion ; GO:0016320 | inferred from sequence or structural similarity with SGD:S000002284 positive regulation of neuron apoptotic process ; GO:0043525 | inferred from genetic interaction with Zzzz\CAG positive regulation of viral entry into host cell ; GO:0046598 | inferred from mutant phenotype fusome ; GO:0045169 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay proteasome complex ; GO:0000502 | non-traceable author statement autolysosome ; GO:0044754 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "ter94, VCP, p97, TER94, dvcp, CG2331, Ter94, DmTER94, l(2)03775, BcDNA.GM02885, Vcp, Apple, 7.12, 22.26, I, BcDNA:GM02885, l(2)46CFf, l(2)46CFs, l(2)46Ch, anon-WO2004063362.67, anon-WO2004063362.65, VCP/p97, pTER94, CDC48, dTERA, dmTERA, Tera, dVCP, VCP ATPase, cdc48, vcp" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR004201:CDC48, domain 2, IPR003338:CDC48, N-terminal subdomain, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005938:AAA ATPase, CDC48 family, IPR009010:Aspartate decarboxylase-like domain, IPR029067:CDC48 domain 2-like, IPR015415:Vps4 oligomerisation, C-terminal" CG2331 11-Aug-17 DroID_v2017_08 "Drer\spata5l1, Drer\vcp, Drer\zgc:136908, Drer\nvl" "Scer\CDC48, Scer\AFG2" "Cele\cdc-48.2, Cele\cdc-48.1, Cele\mac-1" "Xtro\caskin2, Xtro\spata5, Xtro\nvl, Xtro\vcp" "Mmus\Vcp, Mmus\Spata5, Mmus\Clpb, Mmus\Nvl" "Hsap\ATAD2B, Hsap\CLPB, Hsap\SPATA5, Hsap\VCP, Hsap\SPATA5L1, Hsap\NVL" adult stage && oogenesis stage " ovary

, follicle cell

, oocyte

, germarium region 1

, nurse cell

, cystoblast

, cystocyte

" " adult stage | female , adult stage , adult stage && oogenesis stage , embryonic stage && pupal stage && adult stage , adult stage | male , oogenesis stage | stage S1 && adult stage | female " " nurse cell

, mushroom body

, mushroom body alpha-lobe

, antennal glomerulus

, cystocyte

, calyx of mushroom body

, oocyte

, mushroom body beta-lobe

, germarium region 2b

, spermatozoon

, ellipsoid body

, germarium

, fusome

, egg chamber

" DRSC27600 K -0.088808526 -0.421252864 -0.558801738 0.412005237 2.057561479 2.464984974 FBgn0053903 His4:CG33903 His4:CG33903 http://flybase.org/reports/FBgn0053903 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33903, His4:CG33903" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33903 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-36p18.3, Drer\LOC100331412, Drer\si:dkey-108k21.19, Drer\si:ch211-113a14.26, Drer\si:dkey-108k21.12, Drer\si:ch211-113a14.17, Drer\LOC100329358, Drer\LOC794549, Drer\zgc:194989, Drer\si:ch73-368j24.14, Drer\si:ch73-36p18.4, Drer\LOC100150038, Drer\si:ch211-113a14.6, Drer\si:dkey-261m9.17, Drer\si:dkey-261m9.18, Drer\si:dkey-108k21.28, Drer\si:ch73-368j24.1, Drer\LOC562770, Drer\si:dkey-23a13.7, Drer\LOC570405, Drer\zgc:153409, Drer\zgc:154164, Drer\zgc:163040, Drer\hist1h4l" "Scer\HHF2, Scer\HHF1" "Cele\his-46, Cele\his-67, Cele\his-1, Cele\his-37, Cele\his-10, Cele\his-28, Cele\his-38, Cele\his-5, Cele\his-14, Cele\his-60, Cele\his-56, Cele\his-50, Cele\his-26, Cele\his-18, Cele\his-64, Cele\his-31" "Xtro\hist1h4k, Xtro\LOC100493041, Xtro\LOC101734426, Xtro\hist1h4c" "Mmus\Hist1h4f, Mmus\Hist1h4d, Mmus\Hist4h4, Mmus\Hist1h4m, Mmus\Hist1h4c, Mmus\Hist1h4k, Mmus\Hist2h4, Mmus\Hist1h4h, Mmus\Hist1h4j, Mmus\Hist1h4b, Mmus\Hist1h4n, Mmus\Hist1h4i, Mmus\Hist1h4a" "Hsap\HIST1H4L, Hsap\HIST1H4I, Hsap\HIST1H4C, Hsap\HIST1H4G, Hsap\HIST1H4F, Hsap\HIST1H4K, Hsap\HIST1H4J, Hsap\HIST1H4E, Hsap\HIST1H4A, Hsap\HIST1H4H, Hsap\HIST2H4A, Hsap\HIST4H4, Hsap\HIST1H4B, Hsap\HIST2H4B, Hsap\HIST1H4D" FBgn0015286 Rala Ras-like protein A http://flybase.org/reports/FBgn0015286 "FBgn0025241, FBgn0027285, FBgn0028308, FBgn0040134" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from direct assay PDZ domain binding ; GO:0030165 | inferred from physical interaction with Magi GTPase activity ; GO:0003924 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Rlip" negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with N dorsal closure ; GO:0007391 | non-traceable author statement Ras protein signal transduction ; GO:0007265 | inferred from genetic interaction with Rgl border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with bsk inferred from genetic interaction with Jra inferred from genetic interaction with kay inferred from genetic interaction with msn inferred from genetic interaction with Traf4 innate immune response ; GO:0045087 | inferred from direct assay negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with bsk inferred from genetic interaction with hep defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype regulation of cell morphogenesis ; GO:0022604 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | traceable author statement R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "ral, Ral, dRal, Dm RalA, DRala, RalA, Drala, Ral-a, CG2849, DRal, RALA, l(1)G0174, l(1)G0373, l(1)G0501, anon-EST:fe1H4, Rala, Dral, D-RalA, ralA, DralA, 24639550, P48555" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG2849 11-Aug-17 DroID_v2017_08 "Drer\rsg1, Drer\rasl11a, Drer\rasl10a, Drer\zgc:153845, Drer\hrasb, Drer\zgc:110699, Drer\LOC100332969, Drer\diras2, Drer\rap1aa, Drer\si:ch73-116o1.2, Drer\rasl11b, Drer\zgc:114118, Drer\diras1b, Drer\kras, Drer\rasd1, Drer\rem2, Drer\rheb, Drer\rhebl1, Drer\rem1, Drer\si:dkeyp-59c12.1, Drer\zgc:55558, Drer\nras, Drer\rit1, Drer\rap2ab, Drer\rrad, Drer\ralbb, Drer\mras, Drer\rergla, Drer\hrasa, Drer\rap2c, Drer\rap1ab, Drer\rerglb, Drer\rap2b, Drer\ralaa, Drer\zgc:152698, Drer\ralab, Drer\rras, Drer\rras2, Drer\ralba, Drer\si:dkey-27j5.5, Drer\zgc:171704, Drer\gem, Drer\zgc:64022, Drer\diras1a, Drer\rasl12" "Scer\RHB1, Scer\RAS1, Scer\YPT53, Scer\RSR1, Scer\RAS2" "Cele\let-60, Cele\ral-1, Cele\ras-1, Cele\C44B7.12" "Xtro\diras3, Xtro\gem, Xtro\ralb, Xtro\rap2a, Xtro\rerg, Xtro\rap2c, Xtro\rrad, Xtro\rem1, Xtro\LOC733456, Xtro\rap1b, Xtro\rhebl1, Xtro\rheb, Xtro\rem2, Xtro\rap2b, Xtro\rasd1, Xtro\rergl, Xtro\hras, Xtro\ras-dva, Xtro\rasl11b, Xtro\rasd2, Xtro\rasl10a, Xtro\rit1, Xtro\rala, Xtro\nras, Xtro\adal, Xtro\rsg1, Xtro\diras2, Xtro\diras1, Xtro\rap1a, Xtro\kras" "Mmus\Diras1, Mmus\Rem1, Mmus\Rsg1, Mmus\Gm266, Mmus\Rasl11b, Mmus\Rap2c, Mmus\Rras2, Mmus\Rap2a, Mmus\Gem, Mmus\Rerg, Mmus\Hras, Mmus\Rem2, Mmus\Rasd2, Mmus\Rhebl1, Mmus\Rrad, Mmus\Nras, Mmus\Rap1a, Mmus\Mras, Mmus\Rasl10b, Mmus\Rheb, Mmus\Rit2, Mmus\Rasd1, Mmus\Rala, Mmus\Kras, Mmus\Rergl, Mmus\Rasl12, Mmus\Rit1, Mmus\Rasl11a, Mmus\Ralb, Mmus\Diras2, Mmus\Rap2b, Mmus\Rasl10a, Mmus\Eras, Mmus\Rap1b, Mmus\Rras, Mmus\Adal" "Hsap\RRAS2, Hsap\DIRAS2, Hsap\RAP1A, Hsap\RRAD, Hsap\RIT2, Hsap\KRAS, Hsap\RASL10B, Hsap\RALB, Hsap\MRAS, Hsap\RIT1, Hsap\REM2, Hsap\REM1, Hsap\RALA, Hsap\RERG, Hsap\RASL12, Hsap\RASL10A, Hsap\RASD1, Hsap\RAP2C, Hsap\RASL11B, Hsap\RERGL, Hsap\RASL11A, Hsap\ERAS, Hsap\RAP1B, Hsap\DIRAS1, Hsap\RRAS, Hsap\HRAS, Hsap\GEM, Hsap\RAP2A, Hsap\RHEBL1, Hsap\RAP2B, Hsap\RASD2, Hsap\NRAS, Hsap\RHEB, Hsap\RSG1, Hsap\DIRAS3" "viable,visible,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal,lethal - all die before end of P-stage,some die during P-stage,some die during pharate adult stage,increased cell death,somatic clone,male sterile,planar polarity defective,decreased cell size,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,microchaeta,macrochaeta,eye,wing vein,chaeta,embryonic/larval salivary gland,border follicle cell,somatic clone,ommatidium,head bristle,humeral bristle,chaeta & mesothoracic tergum,wing blade,eye photoreceptor cell,ommatidial precursor cluster,dorsal closure embryo,embryonic/first instar larval cuticle,embryonic epidermis,anterior,dorsal,crossvein,wing hair,scutum & trichome69B,scutum & macrochaeta69B,scutum & macrochaeta-537.4,scutum & microchaeta-537.4,scutum & macrochaeta & tormogen cell-537.4,scutum & microchaeta & tormogen cell-537.4,scutum & macrochaeta & trichogen cell-537.4,scutum & microchaeta & trichogen cell-537.4,supernumerary" FBgn0053821 His3:CG33821 His3:CG33821 http://flybase.org/reports/FBgn0053821 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33821, His3:CG33821" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33821 11-Aug-17 DroID_v2017_08 "Drer\h3f3b.1, Drer\si:ch1073-429i10.3, Drer\hist2h3c, Drer\h3f3d, Drer\zgc:113984, Drer\zgc:173552, Drer\cenpa, Drer\hist2h3ca1, Drer\LOC108190746, Drer\h3f3a, Drer\h3f3c, Drer\si:ch73-36p18.2, Drer\zgc:113983, Drer\LOC108190747" "Scer\HHT2, Scer\CSE4, Scer\HHT1" "Cele\his-63, Cele\his-9, Cele\his-42, Cele\his-13, Cele\his-59, Cele\his-74, Cele\his-72, Cele\his-69, Cele\his-71, Cele\his-45, Cele\his-27, Cele\his-32, Cele\his-49, Cele\his-55, Cele\his-17, Cele\his-2, Cele\his-6, Cele\his-25" "Xtro\hist2h3d, Xtro\h3f3b, Xtro\LOC100497127, Xtro\cenpa" "Mmus\Hist1h3e, Mmus\H3f3b, Mmus\Hist1h3a, Mmus\Cenpa, Mmus\Hist1h3f, Mmus\Hist2h3b, Mmus\Hist1h3d, Mmus\Hist1h3b, Mmus\Hist1h3c, Mmus\Hist1h3g, Mmus\Hist2h3c2, Mmus\Hist1h3h, Mmus\Hist2h3c1, Mmus\H3f3a, Mmus\Hist1h3i" "Hsap\HIST1H3J, Hsap\HIST2H3C, Hsap\HIST1H3F, Hsap\HIST1H3D, Hsap\HIST1H3C, Hsap\HIST1H3H, Hsap\H3F3A, Hsap\HIST2H3A, Hsap\HIST1H3A, Hsap\H3F3B, Hsap\HIST1H3B, Hsap\HIST1H3G, Hsap\HIST1H3I, Hsap\HIST3H3, Hsap\HIST2H3D, Hsap\H3F3C, Hsap\CENPA, Hsap\HIST1H3E" FBgn0085747 CR40572 - http://flybase.org/reports/FBgn0085747 rRNA_gene - - - CR40572 - CR40572 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0053845 His3:CG33845 His3:CG33845 http://flybase.org/reports/FBgn0053845 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33845, His3:CG33845" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33845 11-Aug-17 DroID_v2017_08 "Drer\LOC108190747, Drer\si:dkey-23a13.8, Drer\zgc:173552, Drer\h3f3d, Drer\zgc:113983, Drer\LOC108190746, Drer\h3f3a, Drer\h3f3b.1, Drer\zgc:113984, Drer\hist2h3c, Drer\si:ch1073-429i10.3, Drer\cenpa, Drer\hist2h3ca1, Drer\si:ch73-36p18.2, Drer\h3f3c" "Scer\HHT2, Scer\CSE4, Scer\HHT1" "Cele\his-9, Cele\his-13, Cele\his-63, Cele\his-25, Cele\his-59, Cele\his-74, Cele\his-32, Cele\his-2, Cele\his-6, Cele\his-49, Cele\his-27, Cele\his-72, Cele\his-45, Cele\his-69, Cele\his-17, Cele\his-55, Cele\his-71, Cele\his-42" "Xtro\h3f3b, Xtro\cenpa, Xtro\hist2h3d, Xtro\LOC100493100" "Mmus\Hist2h3c2, Mmus\Hist2h3c1, Mmus\H3f3a, Mmus\Hist1h3h, Mmus\Hist1h3a, Mmus\Hist1h3c, Mmus\Hist1h3g, Mmus\H3f3b, Mmus\Hist1h3e, Mmus\Hist1h3b, Mmus\Hist1h3d, Mmus\Cenpa, Mmus\Hist2h3b, Mmus\Hist1h3f, Mmus\Hist1h3i" "Hsap\H3F3A, Hsap\HIST1H3J, Hsap\HIST1H3H, Hsap\HIST1H3B, Hsap\HIST1H3G, Hsap\HIST1H3A, Hsap\HIST2H3A, Hsap\HIST1H3F, Hsap\HIST1H3D, Hsap\HIST1H3I, Hsap\H3F3C, Hsap\HIST1H3C, Hsap\HIST3H3, Hsap\HIST2H3D, Hsap\HIST2H3C, Hsap\HIST1H3E, Hsap\CENPA, Hsap\H3F3B" FBgn0263023 CG43318 - http://flybase.org/reports/FBgn0263023 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43318, CG14876" - CG43318 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0261046 Dscam3 Down syndrome cell adhesion molecule 3 http://flybase.org/reports/FBgn0261046 protein_coding_gene identical protein binding ; GO:0042802 | inferred from physical interaction with Dscam3 nervous system development ; GO:0007399 | inferred from electronic annotation with InterPro:IPR033027 cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR033027 homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred by curator from GO:0042802 integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR033027 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG31190, Dscam3, Dscam-like, CT33960, CG8106, CG12536" "IPR003599:Immunoglobulin subtype, IPR003598:Immunoglobulin subtype 2, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR033027:Down syndrome cell adhesion molecule, IPR013098:Immunoglobulin I-set" CG31190 11-Aug-17 DroID_v2017_08 "Drer\mylkb, Drer\dscama, Drer\mylk4a, Drer\mylka, Drer\chl1a, Drer\mylk3, Drer\dscamb, Drer\dscaml1, Drer\mylk4b, Drer\nfascb" - "Cele\C27B7.7, Cele\ZC373.4, Cele\him-4, Cele\unc-89" "Xtro\mylk, Xtro\dscaml1, Xtro\mylk4, Xtro\dscam, Xtro\mylk3" "Mmus\Psg22, Mmus\Psg16, Mmus\Ceacam1, Mmus\Mylk2, Mmus\Psg17, Mmus\Psg21, Mmus\Ceacam16, Mmus\Ceacam5, Mmus\Psg25, Mmus\Psg23, Mmus\Psg28, Mmus\Mylk, Mmus\Dscaml1, Mmus\Dscam, Mmus\Psg29, Mmus\Psg18, Mmus\Psg19, Mmus\Psg26, Mmus\Lifr, Mmus\Mylk4, Mmus\Mylk3, Mmus\Ceacam2, Mmus\Gm5155, Mmus\Psg27" "Hsap\PSG1, Hsap\CEACAM5, Hsap\HSPG2, Hsap\PSG4, Hsap\MYLK, Hsap\DSCAM, Hsap\DSCAML1, Hsap\CEACAM1, Hsap\LIFR, Hsap\MYLK3, Hsap\CEACAM16, Hsap\MYLK2, Hsap\PSG9, Hsap\MYLK4, Hsap\CEACAM8" FBgn0014272 l(2)talc "lethal (2) tumorous antennal, labial, clypeo-labral imaginal discs" http://flybase.org/reports/FBgn0014272 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc growth ; GO:0007446 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)106/22, l(2)k10622, l(2)talc" - - 11-Aug-17 DroID_v2017_08 - - - - - - "hyperplasia,lethal - all die before end of pupal stage,some die during pupal stage" "eye-antennal disc,labial disc" FBgn0021908 l(2)k11537 lethal (2) k11537 http://flybase.org/reports/FBgn0021908 - gene - - - l(2)k11537 - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0067368 l(2)NC204 lethal (2) NC204 http://flybase.org/reports/FBgn0067368 gene - - - "NC204, l(2)NC204" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0029880 CG14443 - http://flybase.org/reports/FBgn0029880 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 helicase activity ; GO:0004386 | inferred from sequence or structural similarity RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "cg14443, CG14443" "IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG14443 11-Aug-17 DroID_v2017_08 "Drer\ddx59, Drer\tdrd12, Drer\ddx43, Drer\ddx21, Drer\ddx5, Drer\LOC556764, Drer\ddx24" "Scer\DBP3, Scer\DBP2" "Cele\Y54G11A.3, Cele\F55F8.2" "Xtro\ddx21, Xtro\ddx59, Xtro\ddx43, Xtro\gpr149, Xtro\ddx17, Xtro\ddx5" "Mmus\Ddx43, Mmus\Ddx17, Mmus\Tdrd12, Mmus\Ddx50, Mmus\Gpr149, Mmus\Ddx59, Mmus\Ddx21, Mmus\Recql4, Mmus\Ddx24, Mmus\Ddx5" "Hsap\DDX50, Hsap\RECQL4, Hsap\DDX5, Hsap\DDX53, Hsap\DDX24, Hsap\TDRD12, Hsap\DDX21, Hsap\GPR149, Hsap\DDX43, Hsap\DDX59, Hsap\DDX17" viable FBgn0037882 CG17187 - http://flybase.org/reports/FBgn0037882 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "BcDNA:RE47242, CG17187" "IPR001623:DnaJ domain, IPR034254:DNAJC17, RNA recognition motif, IPR000504:RNA recognition motif domain" CG17187 11-Aug-17 DroID_v2017_08 "Drer\dnajc30, Drer\dnajc22, Drer\dnajc17, Drer\dnajc12, Drer\dnajb5, Drer\dnajc30b, Drer\dnajb4, Drer\dnajb2, Drer\dnajb1a, Drer\dnajc4" "Scer\ERJ5, Scer\JJJ1, Scer\SCJ1, Scer\DJP1, Scer\CWC23, Scer\CAJ1, Scer\APJ1" "Cele\dnj-22, Cele\dnj-12, Cele\F54F2.9, Cele\dnj-13, Cele\dnj-1, Cele\dnj-19" "Xtro\dnajc17, Xtro\dnajc4" "Mmus\Dnajc17, Mmus\Dnajc22, Mmus\Dnajb1, Mmus\Dnajb4, Mmus\Dnajb5, Mmus\Dnajc12" "Hsap\DNAJC17, Hsap\DNAJB1, Hsap\DNAJB4, Hsap\DNAJC12, Hsap\DNAJB5, Hsap\DNAJC22" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053862 His2A:CG33862 His2A:CG33862 http://flybase.org/reports/FBgn0053862 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33862, His2A:CG33862" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33862 11-Aug-17 DroID_v2017_08 "Drer\h2afx, Drer\zgc:114037, Drer\si:dkey-261m9.18, Drer\si:dkey-108k21.19, Drer\si:dkey-261m9.15, Drer\si:ch211-113a14.26, Drer\zgc:173652, Drer\LOC100148591, Drer\LOC100334934, Drer\si:ch73-368j24.13, Drer\si:dkey-108k21.26, Drer\zgc:101846, Drer\fbxl6, Drer\si:ch211-113a14.7, Drer\si:ch1073-159d7.11, Drer\si:ch73-36p18.5, Drer\si:dkey-23a13.14, Drer\si:dkey-23a13.7, Drer\si:dkey-261m9.7, Drer\h2afy2, Drer\si:ch1073-159d7.10, Drer\si:ch211-113a14.19, Drer\LOC100332229, Drer\si:dkey-261m9.11, Drer\si:ch211-113a14.11, Drer\si:ch211-113a14.16, Drer\si:dkey-23a13.20, Drer\zgc:110434, Drer\zgc:195633, Drer\si:ch73-368j24.14, Drer\si:dkey-108k21.15, Drer\LOC570115, Drer\zgc:154164" "Scer\HTA1, Scer\HTA2" "Cele\his-30, Cele\his-3, Cele\his-21, Cele\his-35, Cele\his-33, Cele\htas-1, Cele\his-51, Cele\his-57, Cele\his-65, Cele\his-47, Cele\his-19, Cele\his-12, Cele\his-43, Cele\his-7, Cele\his-61, Cele\his-68, Cele\his-16, Cele\his-53" "Xtro\hist1h2ah, Xtro\h2afy, Xtro\hist1h2aa, Xtro\hist1h2aj, Xtro\h2afx, Xtro\hist1h2am, Xtro\hist1h2ad, Xtro\h2afy2, Xtro\h2afj" "Mmus\Hist2h2aa1, Mmus\H2afx, Mmus\H2al2b, Mmus\Hist1h2ah, Mmus\Hist1h2af, Mmus\Gm14920, Mmus\Hist2h2ac, Mmus\H2al1j, Mmus\H2al1n, Mmus\H2afj, Mmus\Hist1h2ap, Mmus\Hist2h3c1, Mmus\H2afb1, Mmus\Hist1h2ao, Mmus\H2afy, Mmus\H2al2c, Mmus\Hist1h2ad, Mmus\H2afb3, Mmus\H2afy2, Mmus\Hist1h2aa, Mmus\Hist1h2an, Mmus\Hist1h2ae, Mmus\Hist1h2ac, Mmus\Hist3h2a, Mmus\Hist2h2aa2, Mmus\Hist2h2ab, Mmus\Hist1h2ai, Mmus\H2afb2, Mmus\Hist1h2ab, Mmus\Hist1h2ak, Mmus\Hist1h2ag" "Hsap\H2AFB3, Hsap\H2AFX, Hsap\HIST1H2AH, Hsap\HIST2H2AA4, Hsap\HIST1H2AA, Hsap\HIST2H2AC, Hsap\HIST1H2AI, Hsap\HIST1H2AK, Hsap\HIST2H2AB, Hsap\HIST1H2AM, Hsap\H2AFB1, Hsap\HIST2H2AA3, Hsap\HIST1H2AB, Hsap\H2AFB2, Hsap\HIST1H2AD, Hsap\HIST1H2AG, Hsap\H2AFY2, Hsap\H2AFJ, Hsap\HIST1H2AC, Hsap\HIST1H2AE, Hsap\H2AFY, Hsap\HIST1H2AL, Hsap\HIST3H2A, Hsap\HIST1H2AJ" FBgn0053856 His2A:CG33856 His2A:CG33856 http://flybase.org/reports/FBgn0053856 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33856, His2A:CG33856" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33856 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113a14.11, Drer\LOC100334934, Drer\LOC100332229, Drer\zgc:195633, Drer\si:ch73-36p18.5, Drer\si:dkey-23a13.7, Drer\h2afy2, Drer\LOC100148591, Drer\h2afx, Drer\si:dkey-108k21.15, Drer\si:dkey-261m9.11, Drer\si:ch211-113a14.16, Drer\si:ch211-113a14.26, Drer\zgc:110434, Drer\zgc:114037, Drer\si:ch73-368j24.15, Drer\si:ch211-113a14.7, Drer\si:dkey-261m9.15, Drer\si:ch73-368j24.14, Drer\si:dkey-23a13.20, Drer\si:ch1073-159d7.11, Drer\si:dkey-261m9.18, Drer\si:dkey-108k21.19, Drer\LOC570115, Drer\fbxl6, Drer\si:ch73-368j24.13, Drer\si:ch211-113a14.19, Drer\zgc:173652, Drer\si:dkey-23a13.14, Drer\si:dkey-108k21.26, Drer\si:ch1073-159d7.10, Drer\zgc:154164, Drer\zgc:101846, Drer\si:dkey-261m9.7" "Scer\HTA1, Scer\HTA2" "Cele\his-19, Cele\his-51, Cele\htas-1, Cele\his-16, Cele\his-30, Cele\his-33, Cele\his-43, Cele\his-3, Cele\his-53, Cele\his-65, Cele\his-47, Cele\his-68, Cele\his-21, Cele\his-12, Cele\his-7, Cele\his-35, Cele\his-61, Cele\his-57" "Xtro\LOC101732908, Xtro\LOC101735276, Xtro\LOC100486008, Xtro\LOC101734842, Xtro\LOC101730817, Xtro\LOC100495187, Xtro\LOC101731897, Xtro\h2afy2, Xtro\LOC101733262, Xtro\hist2h2ab, Xtro\LOC100491383, Xtro\LOC100496919, Xtro\LOC100495988, Xtro\LOC100487067, Xtro\LOC100496244, Xtro\LOC101731006, Xtro\LOC101734285, Xtro\hist1h2aj, Xtro\LOC100494316, Xtro\LOC100485854, Xtro\LOC101735111, Xtro\LOC101731295, Xtro\h2afy, Xtro\LOC101730761, Xtro\LOC101732059, Xtro\hist1h2am, Xtro\LOC100486672, Xtro\LOC100487588, Xtro\LOC101733656, Xtro\h2afj, Xtro\LOC101730371, Xtro\LOC100489065, Xtro\LOC100497614, Xtro\LOC100492873, Xtro\LOC101733880, Xtro\LOC100488021, Xtro\LOC100496752, Xtro\LOC100497241, Xtro\LOC100488903, Xtro\LOC101733986, Xtro\LOC100495625, Xtro\LOC100488074, Xtro\LOC100485548, Xtro\LOC100496440, Xtro\LOC101732823, Xtro\LOC100493706, Xtro\hist1h2ad, Xtro\LOC101734900, Xtro\LOC100485081, Xtro\hist1h2aa, Xtro\LOC101731908, Xtro\hist1h2ah, Xtro\LOC100492975, Xtro\LOC100492813, Xtro\LOC100487632, Xtro\h2afx, Xtro\LOC101730347, Xtro\LOC100496089" "Mmus\Hist1h2ak, Mmus\Hist1h2ai, Mmus\Hist2h2aa2, Mmus\Hist3h2a, Mmus\Hist1h2aa, Mmus\Hist1h2ad, Mmus\Hist1h2ae, Mmus\H2al2c, Mmus\H2afj, Mmus\H2al1j, Mmus\Hist1h2ao, Mmus\Hist2h3c1, Mmus\H2al1n, Mmus\Gm14920, Mmus\H2al2b, Mmus\H2afb3, Mmus\H2afy, Mmus\Hist1h2ag, Mmus\H2afx, Mmus\H2afb2, Mmus\Hist1h2ah, Mmus\Hist1h2af, Mmus\Hist1h2ac, Mmus\Hist2h2ab, Mmus\Hist2h2aa1, Mmus\H2afy2, Mmus\Hist1h2ab, Mmus\Hist2h2ac, Mmus\Hist1h2an, Mmus\H2afb1, Mmus\Hist1h2ap" "Hsap\HIST1H2AC, Hsap\HIST1H2AH, Hsap\HIST2H2AA3, Hsap\HIST3H2A, Hsap\HIST1H2AJ, Hsap\HIST1H2AD, Hsap\HIST2H2AB, Hsap\HIST1H2AK, Hsap\H2AFY2, Hsap\H2AFB2, Hsap\HIST1H2AG, Hsap\HIST2H2AC, Hsap\HIST1H2AI, Hsap\HIST1H2AL, Hsap\HIST1H2AA, Hsap\H2AFJ, Hsap\HIST1H2AB, Hsap\HIST2H2AA4, Hsap\H2AFX, Hsap\H2AFY, Hsap\HIST1H2AM, Hsap\H2AFB3, Hsap\HIST1H2AE, Hsap\H2AFB1" FBgn0003079 Raf Raf oncogene http://flybase.org/reports/FBgn0003079 FBgn0040149 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 mitogen-activated protein kinase kinase binding ; GO:0031434 | inferred from biological aspect of ancestor with PANTHER:PTN002356460 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay MAP kinase kinase kinase activity ; GO:0004709 | inferred from biological aspect of ancestor with PANTHER:PTN002356460 protein binding ; GO:0005515 | inferred from physical interaction with cnk" "regulation of cellular pH ; GO:0030641 | inferred from genetic interaction with Nhe2 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype hemocyte differentiation ; GO:0042386 | inferred from mutant phenotype inferred from genetic interaction with hop lamellocyte differentiation ; GO:0035171 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay gastrulation ; GO:0007369 | inferred from mutant phenotype positive regulation of photoreceptor cell differentiation ; GO:0046534 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | inferred from mutant phenotype hemopoiesis ; GO:0030097 | traceable author statement terminal region determination ; GO:0007362 | inferred from mutant phenotype negative regulation of apoptotic signaling pathway ; GO:2001234 | inferred from genetic interaction with rpr lamellocyte differentiation ; GO:0035171 | traceable author statement border follicle cell migration ; GO:0007298 | inferred from genetic interaction with sl positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with Egfr primary branching, open tracheal system ; GO:0007428 | traceable author statement negative regulation of macroautophagy ; GO:0016242 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype wing and notum subfield formation ; GO:0035309 | inferred from genetic interaction with wg regulation of cell cycle ; GO:0051726 | inferred from direct assay" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:9829 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:9829 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 "raf, Raf, D-Raf, RAF, Draf, draf, l(1)polehole/draf, raf-1, D-raf, DRaf, EG:BACH48C10.3, CG2845, l(1)pole hole, Draf1, D-RAF, l(1)phl, l(1)2Fe, Raf1, raf1, rafl, D-raf1, l(1)polehole, l(1)ph, ph, C110, 11-29, l(1)raf, Draf-1, l(1)G0475, Phl, Raf/phl, phl, DRaf1, lincRNA.937, ph1, dRaf" "IPR000719:Protein kinase domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR003116:Raf-like Ras-binding, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR029071:Ubiquitin-related domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG2845 11-Aug-17 DroID_v2017_08 "Drer\araf, Drer\ntrk3a, Drer\ksr1a, Drer\ksr1b, Drer\braf, Drer\raf1a, Drer\raf1b" Scer\KIN1 "Cele\F22B3.8, Cele\lin-45" "Xtro\araf, Xtro\raf1, Xtro\limk1, Xtro\ksr1, Xtro\braf" "Mmus\Raf1, Mmus\Braf, Mmus\Ksr1, Mmus\Ksr2, Mmus\Araf" "Hsap\KIAA1549, Hsap\KSR1, Hsap\RAF1, Hsap\BRAF, Hsap\KSR2, Hsap\ARAF" " embryonic stage , adult stage && oogenesis stage " oocyte

embryonic stage "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,wild-type,increased cell death,visible,heat sensitive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable,germline clone,terminal phenotype,partially,lethal - all die before end of pupal stage,some die during pupal stage,some die during immature adult stage,rescuable maternal effect,mitotic cell cycle defective,somatic clone,female sterile,dominant,poor,male,lethal - all die before end of P-stage,some die during pharate adult stage,homeotic,endomitotic cell cycle defective,small body,reduced,partially lethal - majority live,large body,cell size defective,developmental rate defective,cell growth defective,tumorigenic,increased cell size,neuroanatomy defective,increased cell number,hyperplasia,conditional,cell polarity defective,decreased cell number" "photoreceptor cell R6,ommatidium,eye,thorax,eye photoreceptor cell,photoreceptor cell R7,cone cell,midgut,embryo,wing vein,heat sensitive,ectopic,dorsal appendage,follicle cell,maternal effect,chorion | maternal effect | heat sensitive,wing disc,anterior compartment,posterior compartment,wing,leg,somatic clone,cephalopharyngeal skeleton,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,prothoracic ventral denticle belt,abdominal 1 ventral denticle belt,posterior,germline clone,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,imaginal disc,testis,spermatocyte,fusome,salivary gland imaginal ring,mitotic cell cycle,embryonic epidermis,embryonic head,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,stage 5 embryo,anterior,photoreceptor cell R8,supernumerary,ventral furrow,central nervous system,peripheral nervous system,chordotonal organ,lateral,ventral midline,dorsal,labral segment,dorsal bridge,embryonic/larval pharynx,hypostomal sclerite,embryonic/larval brain,embryonic/larval optic lobe,embryonic/larval labral segment sense organ,rescuable maternal effect,embryonic/first instar larval cuticle,lamellocyte,hemocyte,filzkorper,abdominal 11 anal tuft,anal pad,spermatocyte fusome,pole cell,salivary gland common duct primordium,gastrula embryo,A1-7 ventral acute muscle 2,precursor,embryonic/larval hemocyte,macrochaeta,photoreceptor cell,ocular segment,telson,bract,mitotic cell cycle | rescuable maternal effect,non-rescuable maternal effect,rhabdomere,interommatidial bristle,morphogenetic furrow,antenna,enterocyte,intestinal stem cell,wing vein L3,adult heart,adult heart muscle,myofilamenttin.C‘î4,cardial cell,nuclear chromosometin.C‘î4,embryonic/larval ganglionic branch,trichome,femur,bract | ectopic & mesothoracic tergumhs.PB,bract | ectopic & wing | dorsalhs.PB,bract | ectopic & costal veinhs.PB,bract | ectopic & wing hinge | dorsalhs.PB,bract | ectopic & halterehs.PB,bract | ectopic & adult external prothoraxhs.PB,bract | ectopic & aristahs.PB,bract | ectopic & genahs.PB,wing sensillum,wing vein L5,wing margin,wing vein L4,mesothoracic tergum,anterior supraalar bristle,posterior supraalar bristle,dorsocentral bristle,macrochaeta & mesothoracic tergum179b,hindgut visceral muscle primordium,tracheal branch primordium,mesothoracic tergum & macrochaeta | ectopic-C253,eye-antennal disc,midline glial cell,mitotic cell cycle | somatic clone,chorion | maternal effect55B,bouton,rhabdomere | supernumeraryhs.2sev,wing cell,adult midgut precursor cell | third instar larval stage,adult Malpighian tubule,conditional,adult midgut precursor cell | prepupal stage P1" DRSC18821 IEK -0.544319869 -2.502655391 -0.614568601 -5.385833486 -1.33915694 -1.784098679 FBgn0040099 lectin-28C lectin-28C http://flybase.org/reports/FBgn0040099 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 galactose binding ; GO:0005534 | inferred from sequence or structural similarity - - "CG7106, AC004723a, AC 004723A, lectin-28C" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG7106 11-Aug-17 DroID_v2017_08 "Drer\selp, Drer\hbl1, Drer\hbl3, Drer\hbl4, Drer\hbl2, Drer\colec11, Drer\clec3ba, Drer\clec11a" - Cele\clec-149 Xtro\colec10 "Mmus\Cd207, Mmus\Asgr1, Mmus\Colec11, Mmus\Klri1, Mmus\Clec11a, Mmus\Sell, Mmus\Sftpa1, Mmus\Klri2, Mmus\Sftpd, Mmus\Mgl2, Mmus\Clec10a, Mmus\Asgr2, Mmus\Mbl1" "Hsap\SFTPA1, Hsap\CLEC4A, Hsap\SFTPD, Hsap\CLEC3A, Hsap\CLEC11A, Hsap\SFTPA2, Hsap\COLEC11, Hsap\MBL2, Hsap\COLEC10" viable FBgn0261705 CG42741 - http://flybase.org/reports/FBgn0261705 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG42741, CG9895, CG34209" IPR013087:Zinc finger C2H2-type CG42741 11-Aug-17 DroID_v2017_08 "Drer\klf7a, Drer\klf5b, Drer\klf12b, Drer\klf1, Drer\klf6a, Drer\klf11b, Drer\klf9, Drer\zgc:153115, Drer\klf7b, Drer\klf5l, Drer\klf11a, Drer\klf2a, Drer\klf6b, Drer\klf17, Drer\klf5a, Drer\klf8, Drer\klf2b, Drer\klf3, Drer\klf4, Drer\klf12a, Drer\klf13" "Scer\FZF1, Scer\AZF1, Scer\COM2" "Cele\sptf-2, Cele\klf-3, Cele\klf-2" "Xtro\klf10, Xtro\klf9, Xtro\klf11, Xtro\klf12, Xtro\klf8, Xtro\znf534, Xtro\klf5, Xtro\klf4, Xtro\klf13, Xtro\klf7, Xtro\klf3, Xtro\klf17, Xtro\klf2" "Mmus\Klf10, Mmus\Klf14, Mmus\Klf12, Mmus\Klf4, Mmus\Klf16, Mmus\Klf8, Mmus\Klf6, Mmus\Klf1, Mmus\Klf9, Mmus\Klf11, Mmus\Klf2, Mmus\Klf7, Mmus\Klf13, Mmus\Klf17, Mmus\Zfp352, Mmus\Klf3, Mmus\Klf5" "Hsap\KLF10, Hsap\KLF2, Hsap\KLF12, Hsap\KLF5, Hsap\KLF14, Hsap\KLF13, Hsap\KLF1, Hsap\KLF3, Hsap\KLF4, Hsap\KLF7, Hsap\KLF8, Hsap\KLF6, Hsap\KLF9, Hsap\KLF16" FBgn0250789 alpha-Spec alpha Spectrin http://flybase.org/reports/FBgn0250789 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity "neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype germ-line cyst formation ; GO:0048134 | traceable author statement ovarian follicle cell development ; GO:0030707 | traceable author statement maintenance of presynaptic active zone structure ; GO:0048790 | inferred from direct assay plasma membrane organization ; GO:0007009 | traceable author statement regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype long-term strengthening of neuromuscular junction ; GO:0042062 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype fusome organization ; GO:0045478 | traceable author statement female germline ring canal formation, actin assembly ; GO:0008302 | NOT traceable author statement negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with β-Spec germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from mutant phenotype oocyte construction ; GO:0007308 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay spectrin ; GO:0008091 | inferred from sequence or structural similarity cell cortex ; GO:0005938 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay spectrosome ; GO:0045170 | inferred from direct assay fusome ; GO:0045169 | spectrosome ; GO:0045170 | "alpha-Spec, alphaSpec, alpha-spec, klo, spectrin, alpha, CG1977, dre3, 3A9, l(3)04276, alpha-Spc, l(3)dre3, l(3)alpha-Spec, l(3)62Bd, anon-EST:fe2E2, alfa-Spec, alpha-spectrin, Spec, alpha-Spe, alpha-Spect, alphaSp, alpha-Sp, FCP-B, alpha-Spectrin, alpha Spectrin, Spectrin, alphaSpectrin, alpha-SPEC, FBtr0072789, alpha spectrin" "IPR018159:Spectrin/alpha-actinin, IPR018247:EF-Hand 1, calcium-binding site, IPR014837:EF-hand, Ca insensitive, IPR013315:Spectrin alpha chain, SH3 domain, IPR011992:EF-hand domain pair, IPR002048:EF-hand domain, IPR002017:Spectrin repeat, IPR001452:SH3 domain" CG1977 11-Aug-17 DroID_v2017_08 "Drer\actn3b, Drer\sptb, Drer\actn2b, Drer\sptbn1, Drer\LOC558044, Drer\zgc:165653, Drer\spna2, Drer\actn3a, Drer\si:dkey-27p18.5, Drer\sptbn5, Drer\ehbp1l1b, Drer\ehbp1, Drer\actn4" - "Cele\sma-1, Cele\spc-1, Cele\unc-70" "Xtro\actn3, Xtro\actn4, Xtro\ehbp1l1, Xtro\ehbp1, Xtro\sptbn2, Xtro\actn1, Xtro\actn2, Xtro\sptbn5, Xtro\sptan1" "Mmus\Actn4, Mmus\Actn2, Mmus\Sptbn1, Mmus\Actn1, Mmus\Sptbn2, Mmus\Sptb, Mmus\Sptan1, Mmus\Sptbn4, Mmus\Actn3, Mmus\Spta1, Mmus\Ehbp1l1, Mmus\Ehbp1" "Hsap\EHBP1, Hsap\ACTN1, Hsap\EHBP1L1, Hsap\SPTAN1, Hsap\ACTN4, Hsap\SPTBN2, Hsap\ACTN2, Hsap\SPTBN4, Hsap\SPTB, Hsap\SPTBN5, Hsap\SPTBN1, Hsap\SPTA1" adult stage germarium && follicle cell

FBgn0053824 His3:CG33824 His3:CG33824 http://flybase.org/reports/FBgn0053824 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33824, His3:CG33824" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33824 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-429i10.3, Drer\h3f3d, Drer\hist2h3c, Drer\h3f3a, Drer\zgc:113984, Drer\h3f3c, Drer\LOC108190746, Drer\hist2h3ca1, Drer\LOC108190747, Drer\si:ch73-36p18.2, Drer\cenpa, Drer\h3f3b.1, Drer\zgc:113983, Drer\zgc:173552" "Scer\CSE4, Scer\HHT1, Scer\HHT2" "Cele\his-71, Cele\his-25, Cele\his-17, Cele\his-42, Cele\his-63, Cele\his-9, Cele\his-74, Cele\his-45, Cele\his-55, Cele\his-49, Cele\his-6, Cele\his-13, Cele\his-2, Cele\his-72, Cele\his-59, Cele\his-27, Cele\his-69, Cele\his-32" "Xtro\cenpa, Xtro\h3f3b, Xtro\hist2h3d, Xtro\LOC100486720" "Mmus\Hist1h3f, Mmus\Hist1h3c, Mmus\Hist1h3g, Mmus\H3f3b, Mmus\H3f3a, Mmus\Hist1h3i, Mmus\Hist2h3c1, Mmus\Hist1h3d, Mmus\Hist1h3h, Mmus\Hist2h3c2, Mmus\H3f3c, Mmus\Hist1h3e, Mmus\Hist2h3b, Mmus\Hist1h3a, Mmus\Cenpa, Mmus\Hist1h3b" "Hsap\HIST1H3E, Hsap\HIST1H3F, Hsap\HIST2H3A, Hsap\HIST3H3, Hsap\HIST1H3D, Hsap\HIST1H3A, Hsap\CENPA, Hsap\HIST2H3D, Hsap\H3F3C, Hsap\HIST1H3C, Hsap\HIST1H3H, Hsap\HIST1H3J, Hsap\HIST1H3B, Hsap\HIST1H3I, Hsap\H3F3B, Hsap\HIST1H3G, Hsap\HIST2H3C, Hsap\H3F3A" FBgn0243512 puc puckered http://flybase.org/reports/FBgn0243512 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 JUN kinase phosphatase activity ; GO:0008579 | traceable author statement phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | non-traceable author statement MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | traceable author statement protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity JUN kinase phosphatase activity ; GO:0008579 | inferred from mutant phenotype "suture of dorsal opening ; GO:0007396 | non-traceable author statement negative regulation of JNK cascade ; GO:0046329 | traceable author statement establishment of planar polarity ; GO:0001736 | non-traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement response to oxidative stress ; GO:0006979 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from expression pattern cellular response to oxidative stress ; GO:0034599 | inferred from direct assay wound healing ; GO:0042060 | inferred from mutant phenotype negative regulation of stress-activated protein kinase signaling cascade ; GO:0070303 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype positive regulation of immune response ; GO:0050778 | inferred from mutant phenotype imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from genetic interaction with slpr determination of digestive tract left/right asymmetry ; GO:0071907 | inferred from mutant phenotype JNK cascade ; GO:0007254 | non-traceable author statement micropyle formation ; GO:0046844 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype positive regulation of border follicle cell migration ; GO:1903688 | inferred from mutant phenotype JNK cascade ; GO:0007254 | traceable author statement actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype epidermis development ; GO:0008544 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | non-traceable author statement protein dephosphorylation ; GO:0006470 | non-traceable author statement protein secretion ; GO:0009306 | inferred from mutant phenotype dorsal closure ; GO:0007391 | non-traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from mutant phenotype imaginal disc fusion ; GO:0046528 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity inferred from direct assay negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype embryonic anterior midgut (ectodermal) morphogenesis ; GO:0048615 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr regulation of cell shape ; GO:0008360 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "puc, Puc, CG7850, PUC, PUC/MKP, l(3)A251.1, hrt, 1351/08, 0238/03, l(3)84Eh, vco, l(3)j4E1, JNK-DSP, puckered" "IPR000387:Tyrosine specific protein phosphatases domain, IPR000340:Dual specificity phosphatase, catalytic domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like" CG7850 11-Aug-17 DroID_v2017_08 "Drer\dusp7, Drer\ssh1b, Drer\dusp16, Drer\si:ch211-195b15.8, Drer\LOC100150565, Drer\si:ch211-121a2.2, Drer\dusp14, Drer\dusp6, Drer\dusp27, Drer\si:ch1073-184j22.2, Drer\dusp2, Drer\dupd1, Drer\si:ch211-223p8.8, Drer\dusp12, Drer\ssh1a, Drer\dusp1, Drer\dusp28, Drer\zgc:153981, Drer\styx, Drer\dusp22a, Drer\dusp3b, Drer\dusp13a, Drer\dusp4, Drer\ssh2b, Drer\dusp3a, Drer\dusp19a, Drer\dusp19b, Drer\ssh2a, Drer\si:dkey-175m17.7, Drer\dusp22b, Drer\dusp5, Drer\dusp10, Drer\zgc:153044, Drer\styxl1, Drer\dusp8b, Drer\dusp8a, Drer\si:ch211-203d1.3" "Scer\SDP1, Scer\PPS1, Scer\MSG5, Scer\YVH1" "Cele\C04F12.8, Cele\Y54F10BM.13, Cele\lip-1, Cele\F13D11.3, Cele\F26A3.4, Cele\vhp-1" "Xtro\ssh2, Xtro\dusp18, Xtro\epm2a, Xtro\dusp1, Xtro\ssh1, Xtro\dusp26, Xtro\dupd1, Xtro\dusp28, Xtro\dusp5, Xtro\dusp4, Xtro\dusp22a, Xtro\styx, Xtro\dusp9, Xtro\styxl1, Xtro\dusp10, Xtro\dusp6, Xtro\dusp22, Xtro\dusp19, Xtro\dusp12" "Mmus\Dusp13, Mmus\Dusp12, Mmus\Dusp26, Mmus\Styxl1, Mmus\Dusp22, Mmus\Dusp3, Mmus\Dusp10, Mmus\Styx, Mmus\Dusp16, Mmus\Dusp1, Mmus\Ssh3, Mmus\Dusp5, Mmus\Dupd1, Mmus\Dusp27, Mmus\Dusp2, Mmus\Dusp19, Mmus\Dusp7, Mmus\Dusp28, Mmus\Dusp18, Mmus\Dusp9, Mmus\Dusp4, Mmus\Dusp14, Mmus\Dusp21, Mmus\Ssh2, Mmus\Ssh1, Mmus\Dusp6, Mmus\Dusp15, Mmus\Dusp8, Mmus\Epm2a" "Hsap\DUSP15, Hsap\DUSP9, Hsap\STYXL1, Hsap\DUSP1, Hsap\SSH2, Hsap\DUSP22, Hsap\EPM2A, Hsap\SSH1, Hsap\STYX, Hsap\DUSP10, Hsap\DUSP4, Hsap\DUSP5, Hsap\DUSP8, Hsap\DUSP14, Hsap\DUSP27, Hsap\DUSP19, Hsap\SSH3, Hsap\DUPD1, Hsap\DUSP2, Hsap\DUSP6, Hsap\DUSP28, Hsap\DUSP3, Hsap\DUSP7, Hsap\DUSP12, Hsap\DUSP21, Hsap\DUSP18, Hsap\DUSP16, Hsap\DUSP26, Hsap\DUSP13" " embryonic stage , embryonic stage | 4-8 hr " epidermis | dorsal

DRSC17034 IEK 0.109788573 -3.882864057 -2.988694496 -2.061521113 1.369600918 1.657226478 FBgn0003410 sina seven in absentia http://flybase.org/reports/FBgn0003410 FBgn0025204 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR013010, InterPro:IPR013323 protein self-association ; GO:0043621 | inferred from physical interaction with sina ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10857 zinc ion binding ; GO:0008270 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with eff inferred from physical interaction with phyl protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q27934" proteolysis ; GO:0006508 | traceable author statement regulation of R7 cell differentiation ; GO:0045676 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from physical interaction with lwr R7 cell fate commitment ; GO:0007465 | traceable author statement sensory organ development ; GO:0007423 | inferred from mutant phenotype proteasomal protein catabolic process ; GO:0010498 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay ubiquitin ligase complex ; GO:0000151 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Sina, sia, CG9949, anon-EST:fe2H7, sina, SINA" "IPR018121:Seven-in-absentia protein, TRAF-like domain, IPR001841:Zinc finger, RING-type, IPR004162:E3 ubiquitin-protein ligase SIN-like, IPR008974:TRAF-like, IPR013010:Zinc finger, SIAH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9949 11-Aug-17 DroID_v2017_08 "Drer\cyhr1, Drer\siah2l, Drer\siah1" - Cele\siah-1 "Xtro\siah1, Xtro\siah2" "Mmus\Siah2, Mmus\6330408A02Rik, Mmus\Siah1b, Mmus\Siah1a, Mmus\Cyhr1, Mmus\Siah3" "Hsap\C19orf68, Hsap\SIAH1, Hsap\CYHR1, Hsap\SIAH3, Hsap\SIAH2" embryonic stage -- adult stage " larval stage | third instar , pupal stage | 40 hr " " embryonic/larval hindgut

, morphogenetic furrow | anterior to

, retina

, embryonic/larval fat body

, cone cell

, photoreceptor cell R3 | presumptive

, photoreceptor cell R1 | presumptive

, peripodial epithelium &&of dorsal mesothoracic disc

, five-cell ommatidial precursor cluster

, embryonic/larval midgut

, peripodial epithelium

, photoreceptor cell R1--8

, peripodial epithelium &&of eye-antennal disc

, ommatidium

, photoreceptor cell R4 | presumptive

, photoreceptor cell R6 | presumptive

, pigment cell

, eye-antennal disc

, photoreceptor cell R7 | presumptive

, morphogenetic furrow | posterior to

, peripodial epithelium &&of ventral thoracic disc

" "viable,wild-type,visible,female sterile,male sterile,hypoactive,recessive,behavior defective,uncoordinated,short lived,sterile" "wing,eye,ommatidium,pigment cell,eye photoreceptor cell,cone cell,photoreceptor cell R7,macrochaeta,photoreceptor cell R1,somatic clone,supernumerary,mesothoracic tergum & microchaeta,adult abdominal segment 3 & microchaeta,adult abdominal segment 4 & microchaeta,mesothoracic tergum & trichogen cell | supernumerary,mesothoracic tergum & tormogen cell | supernumerary,mesothoracic tergum & chaeta,adult abdominal segment 3 & trichogen cell | supernumerary,adult abdominal segment 3 & tormogen cell | supernumerary,adult abdominal segment 3 & chaeta,adult abdominal segment 4 & trichogen cell | supernumerary,adult abdominal segment 4 & tormogen cell | supernumerary,adult abdominal segment 4 & chaeta,trichogen cell,external sensory organ,photoreceptor cell R8 of pale ommatidium,photoreceptor cell R6,microchaeta,medial triple row,dorsal double row,eo neuron,thecogen cell,presumptive embryonic/larval peripheral nervous system,wing margin bristle,chaeta,ectopic" FBgn0053830 His3:CG33830 His3:CG33830 http://flybase.org/reports/FBgn0053830 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33830, His3:CG33830" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33830 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-429i10.3, Drer\zgc:113984, Drer\LOC108190746, Drer\h3f3c, Drer\si:ch73-36p18.2, Drer\LOC108190747, Drer\hist2h3ca1, Drer\h3f3a, Drer\hist2h3c, Drer\zgc:173552, Drer\h3f3b.1, Drer\cenpa, Drer\zgc:113983, Drer\h3f3d" "Scer\CSE4, Scer\HHT2, Scer\HHT1" "Cele\his-49, Cele\his-69, Cele\his-17, Cele\his-74, Cele\his-6, Cele\his-32, Cele\his-2, Cele\his-72, Cele\his-40, Cele\his-45, Cele\his-27, Cele\his-63, Cele\his-9, Cele\his-71, Cele\his-55, Cele\his-25, Cele\his-42, Cele\his-59, Cele\his-13" "Xtro\h3f3b, Xtro\hist2h3d, Xtro\cenpa" "Mmus\Hist1h3i, Mmus\Hist1h3e, Mmus\H3f3b, Mmus\Hist1h3b, Mmus\Hist2h3c2, Mmus\Hist2h3c1, Mmus\Cenpa, Mmus\Hist1h3d, Mmus\Hist1h3c, Mmus\Hist1h3g, Mmus\Hist1h3h, Mmus\H3f3a, Mmus\Hist2h3b, Mmus\Hist1h3f, Mmus\Hist1h3a" "Hsap\HIST2H3D, Hsap\HIST1H3C, Hsap\HIST1H3G, Hsap\HIST1H3E, Hsap\HIST2H3A, Hsap\HIST2H3C, Hsap\H3F3C, Hsap\HIST1H3B, Hsap\HIST1H3D, Hsap\HIST1H3I, Hsap\H3F3A, Hsap\CENPA, Hsap\HIST1H3F, Hsap\H3F3B, Hsap\HIST1H3H, Hsap\HIST1H3A, Hsap\HIST1H3J, Hsap\HIST3H3" FBgn0003308 ry rosy http://flybase.org/reports/FBgn0003308 - protein_coding_gene "xanthine oxidase activity ; GO:0004855 | inferred from electronic annotation with InterPro:IPR014307 electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001041 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR016166 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR016208 xanthine dehydrogenase activity ; GO:0004854 | inferred from sequence or structural similarity with UniProtKB:P22985 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from sequence or structural similarity with UniProtKB:P22985 inferred from sequence or structural similarity with UniProtKB:P47989 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 oxidoreductase activity, acting on the aldehyde or oxo group of donors ; GO:0016903 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 molybdopterin cofactor binding ; GO:0043546 | inferred from sequence or structural similarity with UniProtKB:P22985 inferred from sequence or structural similarity with UniProtKB:P47989 xanthine dehydrogenase activity ; GO:0004854 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 flavin adenine dinucleotide binding ; GO:0050660 | inferred from sequence or structural similarity with UniProtKB:P22985 inferred from sequence or structural similarity with UniProtKB:P47989" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002346, InterPro:IPR002888, InterPro:IPR008274, InterPro:IPR014307, InterPro:IPR016166, InterPro:IPR016167, InterPro:IPR016208, InterPro:IPR022407 response to ethanol ; GO:0045471 | inferred from mutant phenotype tryptophan metabolic process ; GO:0006568 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | traceable author statement arginine metabolic process ; GO:0006525 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype pyrimidine nucleobase metabolic process ; GO:0006206 | inferred from mutant phenotype xanthine catabolic process ; GO:0009115 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 xanthine catabolic process ; GO:0009115 | inferred from sequence or structural similarity with UniProtKB:P22985 glycerophospholipid metabolic process ; GO:0006650 | inferred from mutant phenotype purine nucleobase metabolic process ; GO:0006144 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000225632 microtubule associated complex ; GO:0005875 | inferred from direct assay "XDH, Xdh, XOR, Xdh/ry, CG7642, ry, xdh, Ry" "IPR000674:Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR002346:Molybdopterin dehydrogenase, FAD-binding, IPR002888:[2Fe-2S]-binding, IPR005107:CO dehydrogenase flavoprotein, C-terminal, IPR006058:2Fe-2S ferredoxin, iron-sulphur binding site, IPR008274:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding, IPR012675:Beta-grasp domain, IPR014307:Xanthine dehydrogenase, small subunit, IPR016166:FAD-binding, type 2, IPR016167:FAD-binding, type 2, subdomain 1, IPR016169:CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR016208:Aldehyde oxidase/xanthine dehydrogenase, IPR022407:Oxidoreductase, molybdopterin binding site" CG7642 11-Aug-17 DroID_v2017_08 "Drer\aox6, Drer\xdh, Drer\aox5" - "Cele\F15E6.6, Cele\F55B11.1, Cele\gad-3" Xtro\xdh "Mmus\Xdh, Mmus\Aox4, Mmus\Aox1, Mmus\Aox2, Mmus\Aox3" "Hsap\XDH, Hsap\AOX1" secondary pigment cell pigment granule

"electrophoretic variant,partially lethal - majority die,partially,recessive,heat sensitive,eye color defective,wild-type,viable,chemical sensitive,radiation sensitive,fertile,short lived,male" "pigment cell,Malpighian tubule" FBgn0004956 upd1 unpaired 1 http://flybase.org/reports/FBgn0004956 "FBgn0003012, FBgn0003956, FBgn0016985" protein_coding_gene receptor binding ; GO:0005102 | traceable author statement receptor binding ; GO:0005102 | non-traceable author statement morphogen activity ; GO:0016015 | non-traceable author statement cytokine activity ; GO:0005125 | inferred from direct assay cytokine activity ; GO:0005125 | traceable author statement "embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from electronic annotation with InterPro:IPR031901 long-term memory ; GO:0007616 | inferred from mutant phenotype stem cell division ; GO:0017145 | traceable author statement negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | traceable author statement regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype sex determination, establishment of X:A ratio ; GO:0007540 | non-traceable author statement JAK-STAT cascade ; GO:0007259 | traceable author statement ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype somatic stem cell division ; GO:0048103 | traceable author statement sex determination ; GO:0007530 | non-traceable author statement intestinal epithelial structure maintenance ; GO:0060729 | inferred from mutant phenotype positive regulation of activation of Janus kinase activity ; GO:0010536 | inferred from direct assay mediolateral intercalation ; GO:0060031 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | traceable author statement locomotor rhythm ; GO:0045475 | inferred from mutant phenotype primary sex determination ; GO:0007538 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype apical constriction ; GO:0003383 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | traceable author statement intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype stem cell division ; GO:0017145 | inferred from mutant phenotype paracrine signaling ; GO:0038001 | inferred from direct assay positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from direct assay border follicle cell migration ; GO:0007298 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:A1YK24,UniProtKB:B8A421,UniProtKB:Q9VCH5 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from direct assay inferred from mutant phenotype inferred from genetic interaction with hop inferred from genetic interaction with Stat92E inferred from genetic interaction with Socs36E inferred from genetic interaction with dome inferred from genetic interaction with Ptp61F" extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | traceable author statement extracellular matrix ; GO:0031012 | inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | traceable author statement apical part of cell ; GO:0045177 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "upd, Upd, CG5993, sisC, sis-c, unp, UPD, sis-C, od, upa, sy, Os, upd1, Upd1, OS, os, l(1)YC43, l(1)YM55, odsy" IPR031901:Unpaired protein CG5993 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 4,5 , embryonic stage | stage >8 , embryonic stage | stage 6,7 " "

pair rule , embryonic/larval tracheal pit

,

segment polarity " "visible,locomotor rhythm defective,RU486 conditional,hyperplasia,memory defective,recessive,lethal,planar polarity defective,somatic clone,cell shape defective,lethal - all die before end of embryonic stage,some die during embryonic stage,increased cell number,male sterile,lethal - all die before end of pupal stage,some die during pupal stage,viable,reduced,female sterile,developmental rate defective,partially lethal - majority die,size defective,cell non-autonomous,mitotic cell cycle defective,increased cell growth,immune response defective,conditional" "eye,wing,wing disc,border follicle cell,somatic clone,gonad | ectopic & embryo,ommatidium,embryonic abdominal segment 4,embryonic abdominal segment 5,ectoderm,polar follicle cell,interfollicle cell,supernumerary,egg chamber,oocyte,eye-antennal disc,eye disc,embryonic/larval cuticle,mesothoracic segment,abdominal segment 4,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,larval head,eye disc anterior to the morphogenetic furrow,tergite,denticle belt & abdominal segment 4,denticle belt & abdominal segment 5,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 8,adult abdominal segment,embryonic segment,plasmatocyte,embryonic/larval proventriculus,ectopic,cuticle & adult external headey.PH,morphogenetic furrow,testis,germline stem cell,male germline stem cell,primary gonial cell,cyst progenitor cell,spermatogonium,round stem cell fusome,cyst cell,stem cell fusome,germline cell | embryonic stage,eye disc | third instar larval stage,photoreceptor cell R8,cell non-autonomous,somatic clone | third instar larval stage,dorsal,ventral,centripetally migrating follicle cell,oocyte associated follicle cell,embryonic head,extended germ band embryo,amnioserosa,embryonic hindgut,pole cell,germarium,germline cyst,female germline stem cell,ovariole,escort stem cell,intestinal stem cell,male germline cell,somatic cell of testis,posterior,adult midgut epithelium" FBgn0010300 brat brain tumor http://flybase.org/reports/FBgn0010300 "FBgn0002034, FBgn0004827, FBgn0027355" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315 translation regulator activity ; GO:0045182 | traceable author statement translation repressor activity ; GO:0030371 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P25724 inferred from physical interaction with UniProtKB:Q8MQJ9 protein binding ; GO:0005515 | inferred from physical interaction with eIF4EHP segmentation ; GO:0035282 | inferred from mutant phenotype regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype asymmetric neuroblast division resulting in ganglion mother cell formation ; GO:0055060 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of synaptic vesicle endocytosis ; GO:1900242 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype rRNA transcription ; GO:0009303 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype ganglion mother cell fate determination ; GO:0007402 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype neuron differentiation ; GO:0030182 | inferred from mutant phenotype regulation of translation ; GO:0006417 | traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype apical cortex ; GO:0045179 | colocalizes_with inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay basal cortex ; GO:0045180 | colocalizes_with inferred from direct assay "CG10719, Brat, l(2)37Cf, Cf, l(2)E60, l(2)brat, fs(2)ltoPM43, anon-37CDa, E60, brat, BRAT, lincRNA.S1565" "IPR000315:B-box-type zinc finger, IPR013017:NHL repeat, subgroup, IPR011042:Six-bladed beta-propeller, TolB-like, IPR001258:NHL repeat" CG10719 11-Aug-17 DroID_v2017_08 "Drer\ftr72, Drer\trim35-27, Drer\si:dkey-46i9.6, Drer\si:ch73-106l15.2, Drer\btr24, Drer\trim59, Drer\trim35-25, Drer\trim3b, Drer\trim35-39, Drer\si:ch211-247l8.10, Drer\si:dkey-37m8.11, Drer\zgc:173581, Drer\btr21, Drer\trim32, Drer\btr07, Drer\trim13, Drer\trim35-19, Drer\trim35-22, Drer\trim25, Drer\si:ch211-120g10.1, Drer\si:ch1073-324l1.1, Drer\ftr87, Drer\ftr82, Drer\zgc:194990, Drer\btr16, Drer\si:ch73-166o21.1, Drer\si:ch211-276c2.4, Drer\trim105, Drer\si:ch211-175l6.2, Drer\trim35-33, Drer\ftr84, Drer\ftr91, Drer\trim35-30, Drer\si:ch211-12p12.2, Drer\btr05, Drer\btr12, Drer\ftr14l, Drer\btr32, Drer\si:ch73-364h19.2, Drer\trim35-13, Drer\btr04, Drer\trim35-21, Drer\trim35-14, Drer\trim35-3, Drer\trim2b, Drer\trim35-10, Drer\ftr73, Drer\trim35-23, Drer\trim35-29, Drer\btr02, Drer\trim35-7, Drer\trim35-35, Drer\trim35-12, Drer\trim35-40, Drer\zmp:0000001316, Drer\btr18, Drer\trim35-31, Drer\btr33, Drer\btr22, Drer\ftr83, Drer\trim35-36, Drer\trim45, Drer\ftr88, Drer\btr01, Drer\trim2a, Drer\trim35-24, Drer\si:ch211-247l8.8, Drer\trim62, Drer\si:ch211-193i15.2, Drer\trim35-34, Drer\btr09, Drer\ftr76, Drer\btr20, Drer\si:dkey-219e21.2, Drer\btr26, Drer\btr06, Drer\trim35-20, Drer\trim3a, Drer\ftr85, Drer\ftr86, Drer\btr29" Scer\PSH1 "Cele\ncl-1, Cele\nhl-1, Cele\nhl-2, Cele\lin-41" "Xtro\trim3, Xtro\trim2, Xtro\trim32" "Mmus\Trim41, Mmus\Trim45, Mmus\Trim3, Mmus\Trim62, Mmus\Trim35, Mmus\Trim2, Mmus\Trim14, Mmus\Trim56, Mmus\Trim29, Mmus\Trim65, Mmus\Trim13, Mmus\Nhlrc4, Mmus\Trim44, Mmus\Trim32, Mmus\Trim25" "Hsap\TRIM14, Hsap\TRIM13, Hsap\TRIM3, Hsap\TRIM44, Hsap\TRIM45, Hsap\TRIM35, Hsap\TRIM29, Hsap\TRIM32, Hsap\TRIM62, Hsap\TRIM65, Hsap\TRIM2, Hsap\TRIM41, Hsap\TRIM25, Hsap\TRIM56, Hsap\NHLRC4" " embryonic stage | stage >=11 , embryonic stage | stage >=12 , embryonic stage | stage 16 , embryonic stage | stage 13-16 " " embryonic ventral nervous system

, embryonic peripheral nervous system

, embryonic brain

, peripheral nervous system precursor cluster

, antenno-maxillary complex

, embryonic ganglion mother cell

" "neuroanatomy defective,somatic clone,viable,fertile,lethal,recessive,tumorigenic,decreased cell number,female sterile,wild-type,mitotic cell cycle defective,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,maternal effect,neurophysiology defective,endocytosis defective,heat sensitive,partially lethal - majority die,increased cell size,increased cell number,visible,cell non-autonomous" "embryonic/larval brain,embryonic epidermis,embryonic abdominal segment,embryonic abdomen,type II neuroblast,supernumerary,female germline stem cell,egg chamber,female germline cyst,female germline cell,germarium,embryo,germline clone,maternal effect,posterior,neuroblast,somatic clone,axon | somatic clone,NMJ bouton,synaptic vesicle,presynaptic active zone membrane,postsynaptic density,wing & trichogen cell,adult thorax,nucleolus | somatic clone,cell autonomous,adult brain,ganglion mother cell,imaginal disc,RP2 motor neuron,neuron,mitotic cell cycle | somatic clone,eye,1st posterior cell,wing,anterior compartment,cell non-autonomous,embryonic/larval neuroblast,supernumerary | third instar larval stage" DRSC03497 IEK 0.919362124 -2.082503528 2.188936656 -2.667520671 0.900406851 1.6821938 FBgn0020309 crol crooked legs http://flybase.org/reports/FBgn0020309 "FBgn0010573, FBgn0010685, FBgn0025949, FBgn0025978" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "lateral inhibition ; GO:0046331 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inferred from genetic interaction with if inferred from genetic interaction with mys cell adhesion ; GO:0007155 | inferred from mutant phenotype positive regulation of mitotic cell cycle ; GO:0045931 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with arm inferred from genetic interaction with Axn regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay "CG14938, crol gamma, crol beta, crol alpha, clone 2.48, clone 1.74, anon-EST:Liang-2.48, anon-EST:Liang-1.74, l(2)s2346, l(2)04418, crol, Crol, ORE-15" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG14938 11-Aug-17 DroID_v2017_08 "Drer\znf384l, Drer\znf366, Drer\drl, Drer\znf362b, Drer\si:rp71-1g18.1, Drer\zgc:113220, Drer\vezf1b, Drer\si:dkey-261j4.5, Drer\znf362a, Drer\gtf3aa, Drer\znf983, Drer\zgc:165515, Drer\si:dkey-33c14.6, Drer\si:ch211-119o8.6, Drer\zgc:66448" "Scer\ZAP1, Scer\PZF1, Scer\AZF1" "Cele\eor-1, Cele\lin-29, Cele\fezf-1, Cele\Y55F3AM.14, Cele\ehn-3, Cele\ztf-25, Cele\Y48G8AL.10, Cele\ztf-28, Cele\egl-43, Cele\sem-4, Cele\Y5F2A.4" "Xtro\LOC100489238, Xtro\znf384, Xtro\maz, Xtro\znf217, Xtro\znf362, Xtro\gtf3a, Xtro\vezf1" "Mmus\Gm14139, Mmus\Zfp532, Mmus\Zfp553, Mmus\Zfp820, Mmus\Zfp93, Mmus\Zfp273, Mmus\Gm4724, Mmus\Zfp90, Mmus\Gtf3a, Mmus\Zfp35, Mmus\AI987944, Mmus\Zfp623, Mmus\Zfp442, Mmus\Zkscan7, Mmus\Zfp420, Mmus\Zfp14, Mmus\Gm14322, Mmus\D130040H23Rik, Mmus\0610010B08Rik, Mmus\Zfp715, Mmus\Zfp943, Mmus\Gm6710, Mmus\Zfp981, Mmus\Zfp65, Mmus\Zfp82, Mmus\Gm14325, Mmus\Zfp788, Mmus\Gm14391, Mmus\LOC101056073, Mmus\Zfp689, Mmus\Zfp111, Mmus\Zfp109, Mmus\Gm14305, Mmus\Zfp967, Mmus\Zfp984, Mmus\Zfp182, Mmus\Zfp52, Mmus\Zfp987, Mmus\Zfp119a, Mmus\Zfp105, Mmus\Zfp612, Mmus\Zfp72, Mmus\AW146154, Mmus\Repin1, Mmus\Zfp748, Mmus\Zfp189, Mmus\Zfp119b, Mmus\Zfp112, Mmus\Zfp791, Mmus\Zfp345, Mmus\Zfp729a, Mmus\Zfp51, Mmus\Zfp846, Mmus\Gm10324, Mmus\Zfp37, Mmus\Zfp944, Mmus\Zfp59, Mmus\Zfp27, Mmus\Zfp382, Mmus\Zfp960, Mmus\Zfp968, Mmus\Zfp160, Mmus\Zfp738, Mmus\Zfp28, Mmus\Zfp617, Mmus\Zfp658, Mmus\Zfp933, Mmus\Zfp235, Mmus\Zfp971, Mmus\Zfp992, Mmus\Zfp947, Mmus\Zfp606, Mmus\Zfp11, Mmus\Zkscan16, Mmus\Zfp934, Mmus\Zfp879, Mmus\Zfp458, Mmus\Zfp60, Mmus\Zfp760, Mmus\Zfp2, Mmus\Zfp287, Mmus\Gm14308, Mmus\Zfp473, Mmus\Zfp334, Mmus\Zfp607b, Mmus\Zfp959, Mmus\Gm14124, Mmus\LOC102633156, Mmus\Zfp251, Mmus\Zfp551, Mmus\Zfp758, Mmus\Zfp932, Mmus\Zfp938, Mmus\Zfp808, Mmus\Zfp595, Mmus\Zfp975, Mmus\Zfp974, Mmus\Zfp53, Mmus\Zfp970, Mmus\Zfp366, Mmus\Zfp85, Mmus\Zfp30, Mmus\Zfp994, Mmus\Zfp629, Mmus\Zfp937, Mmus\Zfp930, Mmus\Zfp114, Mmus\Zfp583, Mmus\Zfp87, Mmus\Zfp39, Mmus\Zfp26, Mmus\Zfp872, Mmus\Zfp729b, Mmus\Zfp362, Mmus\Zfp958, Mmus\Zfp819, Mmus\Zfp184, Mmus\4930522L14Rik, Mmus\Vezf1, Mmus\Zfp709, Mmus\Rex2, Mmus\Zfp180, Mmus\Zfp759, Mmus\Zfp605, Mmus\Zfp457, Mmus\Zfp78, Mmus\Zfp873, Mmus\Zfp945, Mmus\Zfp980, Mmus\Gm13212, Mmus\Zfp560, Mmus\Zfp354c, Mmus\Zfp229, Mmus\Zfp677, Mmus\Zfp946, Mmus\Zfp790, Mmus\D3Ertd254e, Mmus\Zfp74, Mmus\Zfp708, Mmus\Zfp985, Mmus\Zfp712, Mmus\Rbak, Mmus\Zfp619, Mmus\Zfp607a, Mmus\Zfp936, Mmus\Gm14326, Mmus\Zfp418, Mmus\Zfp942, Mmus\Zfp341, Mmus\Zfp260, Mmus\Zfp948, Mmus\Maz, Mmus\Zfp54, Mmus\Zfp647, Mmus\Zfp719, Mmus\Zfp976, Mmus\Zfp7, Mmus\Zkscan1, Mmus\Zfp991, Mmus\Zfp40, Mmus\Zfp616, Mmus\Zfp780b, Mmus\Zfp600, Mmus\Gm10778, Mmus\Zfp534, Mmus\Zfp62, Mmus\Zfp799, Mmus\Zfp710, Mmus\Zfp12, Mmus\Zfp451" "Hsap\ZNF93, Hsap\ZNF429, Hsap\ZNF300, Hsap\ZNF737, Hsap\ZNF451, Hsap\ZNF468, Hsap\ZNF92, Hsap\ZNF594, Hsap\ZNF530, Hsap\ZNF132, Hsap\ZNF823, Hsap\ZNF43, Hsap\ZNF34, Hsap\VEZF1, Hsap\ZNF234, Hsap\ZNF233, Hsap\ZNF7, Hsap\ZNF420, Hsap\ZNF441, Hsap\ZFP28, Hsap\ZNF528, Hsap\ZNF586, Hsap\ZNF224, Hsap\ZNF614, Hsap\ZNF382, Hsap\ZNF26, Hsap\ZNF347, Hsap\ZNF433, Hsap\ZNF600, Hsap\ZNF805, Hsap\ZNF606, Hsap\ZNF141, Hsap\ZNF658, Hsap\ZNF418, Hsap\ZNF267, Hsap\ZNF557, Hsap\ZNF160, Hsap\ZNF615, Hsap\ZNF699, Hsap\ZNF543, Hsap\ZNF497, Hsap\ZNF879, Hsap\ZNF136, Hsap\ZNF417, Hsap\ZNF573, Hsap\ZNF480, Hsap\ZNF548, Hsap\ZNF484, Hsap\ZNF354C, Hsap\ZNF384, Hsap\ZNF680, Hsap\ZNF189, Hsap\ZNF776, Hsap\ZNF717, Hsap\ZNF490, Hsap\ZNF85, Hsap\ZNF81, Hsap\ZNF778, Hsap\ZNF560, Hsap\ZNF613, Hsap\ZNF211, Hsap\ZNF814, Hsap\ZNF565, Hsap\ZNF700, Hsap\ZNF732, Hsap\ZNF623, Hsap\ZNF529, Hsap\ZNF362, Hsap\ZNF563, Hsap\ZNF792, Hsap\ZNF510, Hsap\ZNF479, Hsap\ZNF679, Hsap\ZFP62, Hsap\ZNF35, Hsap\ZNF782, Hsap\ZNF630, Hsap\ZNF235, Hsap\ZNF676, Hsap\ZNF366, Hsap\ZNF473, Hsap\ZNF567, Hsap\ZNF98, Hsap\ZNF83, Hsap\ZNF264, Hsap\ZNF790, Hsap\ZNF383, Hsap\ZNF251, Hsap\ZKSCAN7, Hsap\ZNF256, Hsap\ZNF470, Hsap\ZNF799, Hsap\ZNF320, Hsap\ZNF71, Hsap\ZNF729, Hsap\ZNF284, Hsap\ZNF880, Hsap\ZFP2, Hsap\ZNF443, Hsap\ZNF649, Hsap\ZNF273, Hsap\ZNF112, Hsap\ZFP90, Hsap\ZNF229, Hsap\ZNF780A, Hsap\ZNF570, Hsap\ZNF626, Hsap\ZNF527, Hsap\ZNF749, Hsap\ZNF28, Hsap\ZNF45, Hsap\ZNF689, Hsap\ZNF226, Hsap\ZNF599, Hsap\ZNF629, Hsap\ZNF865, Hsap\ZNF583, Hsap\ZNF730, Hsap\ZNF665, Hsap\ZNF791, Hsap\ZNF33A, Hsap\ZNF878, Hsap\ZNF587, Hsap\ZNF222, Hsap\ZNF624, Hsap\ZFP30, Hsap\ZFP14, Hsap\ZNF682, Hsap\ZNF534, Hsap\ZNF91, Hsap\ZNF208, Hsap\ZNF107, Hsap\ZNF416, Hsap\ZNF155, Hsap\ZNF765, Hsap\ZNF257, Hsap\ZNF709, Hsap\ZNF568, Hsap\MAZ, Hsap\ZNF483, Hsap\ZNF431, Hsap\ZNF607, Hsap\ZNF627, Hsap\ZNF585A, Hsap\ZNF460, Hsap\ZNF430, Hsap\ZNF12, Hsap\ZNF44, Hsap\ZNF540, Hsap\ZNF260, Hsap\ZNF841, Hsap\ZNF182, Hsap\ZNF860, Hsap\ZNF611, Hsap\ZNF16, Hsap\ZNF552, Hsap\REPIN1, Hsap\ZNF708, Hsap\ZNF23, Hsap\ZNF117, Hsap\ZNF571, Hsap\ZNF816, Hsap\ZNF20, Hsap\ZNF506, Hsap\ZNF254, Hsap\ZNF701, Hsap\ZNF440, Hsap\ZNF695, Hsap\ZNF180, Hsap\ZNF225, Hsap\ZNF808, Hsap\ZNF845, Hsap\ZNF546, Hsap\ZSCAN26, Hsap\ZNF677, Hsap\ZNF605, Hsap\ZNF569, Hsap\ZNF549, Hsap\ZNF555, Hsap\ZNF331, Hsap\ZNF77, Hsap\ZNF135, Hsap\ZNF84, Hsap\ZNF337, Hsap\ZNF551, Hsap\ZNF850, Hsap\ZNF70, Hsap\ZNF41, Hsap\ZNF780B, Hsap\ZNF461, Hsap\ZNF544, Hsap\ZNF69, Hsap\ZNF195, Hsap\ZSCAN2, Hsap\ZNF33B, Hsap\ZNF184, Hsap\ZNF493, Hsap\ZNF99, Hsap\ZNF175, Hsap\ZNF439, Hsap\ZNF227, Hsap\ZNF716, Hsap\ZNF442, Hsap\ZNF268, Hsap\ZNF79, Hsap\GTF3A, Hsap\ZNF710, Hsap\ZNF616, Hsap\ZNF287, Hsap\ZNF678, Hsap\ZNF763, Hsap\ZNF502, Hsap\ZNF766, Hsap\ZKSCAN1, Hsap\ZNF471, Hsap\ZNF681, Hsap\ZNF250, Hsap\ZNF836, Hsap\ZNF852, Hsap\ZNF223, Hsap\ZNF813, Hsap\ZNF14, Hsap\ZNF304, Hsap\ZNF492, Hsap\ZNF30, Hsap\ZNF714, Hsap\RBAK, Hsap\ZNF675, Hsap\ZNF197" " larval stage | third instar , prepupal stage " "viable,fertile,lethal,recessive,mitotic cell cycle defective,somatic clone,long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective,female limited,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,visible,increased cell death,cell death defective,partially lethal - majority die" "wing vein,ectopic,ventral thoracic disc,leg,wing,femur,wing pouch,somatic clone,macrochaeta,stage P5 pupa,pupa,adult head,stage P14 pharate adult,metathoracic leg,metathoracic femur,metathoracic leg sensillum,intersegmental nerve,posterior compartment,wing disc,morphogenetic furrow,chaeta,supernumerary,mesothoracic tergum" DRSC21348 K -0.963320905 -0.071652027 -0.315914999 1.041765843 -1.634031783 -1.546821786 FBgn0004378 Klp61F Kinesin-like protein at 61F http://flybase.org/reports/FBgn0004378 "FBgn0004923, FBgn0010911, FBgn0015744" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule binding ; GO:0008017 | inferred from direct assay ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from direct assay motor activity ; GO:0003774 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from biological aspect of ancestor with PANTHER:PTN000649234 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P54350" Golgi organization ; GO:0007030 | inferred from mutant phenotype plus-end directed microtubule sliding ; GO:0031535 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from direct assay adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype mitotic centrosome separation ; GO:0007100 | inferred from mutant phenotype inferred from genetic interaction with ncd protein homotetramerization ; GO:0051289 | inferred from direct assay microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity centrosome separation ; GO:0051299 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000649235 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from biological aspect of ancestor with PANTHER:PTN000649235 microtubule bundle formation ; GO:0001578 | inferred from direct assay fusome organization ; GO:0045478 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype positive regulation of Golgi to plasma membrane protein transport ; GO:0042998 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype fusome ; GO:0045169 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity spindle ; GO:0005819 | inferred from direct assay mitotic spindle pole ; GO:0097431 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay mitotic spindle microtubule ; GO:1990498 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay aster ; GO:0005818 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay centrosome ; GO:0005813 | colocalizes_with inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay "KLP61f, klp61f, DmKLP61F, KLP61F, CG9191, DmKlp61F, Klp61F/KRP130, KLP61, 6345, KRP[[130]], KRP130, DmKRP130, urcn, KRP[[(130)]], KLP2, urc, l(3)07012, Krp130, Klp2, Klp61F, CG9191-PA, klp61F, Klp61f, l(3)6D283, l(3)Klp61F, Klp 61F, KIF 8, Kin-5, KIF11" "IPR025901:Kinesin-associated microtubule-binding domain, IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9191 11-Aug-17 DroID_v2017_08 "Drer\kif3a, Drer\kif11" "Scer\CIN8, Scer\KIP1" "Cele\klp-20, Cele\bmk-1" Xtro\kif11 "Mmus\Kif11, Mmus\Kif3a" "Hsap\KIF11, Hsap\KIF3A" " embryonic stage && larval stage && pupal stage , adult stage | female , adult stage | male , embryonic stage , embryonic stage | stage 6 " " ovary

, testis

, ventral midline

, ventral nervous system | restricted

, mesoderm anlage

, cephalic furrow

" "viable,fertile,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,cytokinesis defective,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,neuroanatomy defective" "spindle | embryonic stage,spindle | embryonic stage, with Klp61F07012,spermatocyte fusome,nuclear chromosome,embryonic/larval brain,imaginal disc,centriole & spermatocyte,aster & spermatocyte,spindle & spermatocyte,centrosome & spermatocyte,spermatocyte,spermatid,spindle,mitotic cell cycle & spermatocyte,meiotic telophase II & spermatocyte,nuclear lamina & spermatocyte,spindle & neuroblast & larva,nuclear lamina & neuroblast & larva,aster & neuroblast & larva,centrosome & neuroblast & larva,embryonic/larval neuroblast,spindle | pre-blastoderm stage,spindle microtubule | embryonic stage 4,aster & spermatocytebab-PG),spindle & spermatocytebab-PG),centrosome & spermatocytebab-PG),microtubule organizing center | pre-blastoderm stage,spindle | embryonic stage, with Klp61FUbi-p63E.TAvicGFP/Klp61F06836,testis,larval brain & nuclear chromosome & larva,somatic clone,spindle microtubule,astral microtubule,mitosis & nuclear chromosome,spindle pole,S2 cell-line,ganglion mother cell" DRSC08671 IE 1.72234719 -2.332438086 0.869235011 -3.139821157 0.143621329 1.224654645 FBgn0283472 S6k Ribosomal protein S6 kinase http://flybase.org/reports/FBgn0283472 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017892 ribosomal protein S6 kinase activity ; GO:0004711 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 ribosomal protein S6 kinase activity ; GO:0004711 | inferred from sequence or structural similarity inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Tak1" dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype multicellular organism growth ; GO:0035264 | inferred from mutant phenotype growth ; GO:0040007 | inferred from mutant phenotype response to nutrient ; GO:0007584 | traceable author statement positive regulation of macroautophagy ; GO:0016239 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | non-traceable author statement positive regulation of cell growth ; GO:0030307 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype positive regulation of organ growth ; GO:0046622 | non-traceable author statement larval feeding behavior ; GO:0030536 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype positive regulation of growth ; GO:0045927 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of organ growth ; GO:0046622 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity regulation of response to drug ; GO:2001023 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | non-traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | traceable author statement myoblast fusion ; GO:0007520 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with Rheb positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement lipid metabolic process ; GO:0006629 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype inferred from genetic interaction with gig response to oxidative stress ; GO:0006979 | inferred from direct assay regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 nucleoplasm ; GO:0005654 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "S6k, S6K, dS6K, S6K1, s6k, p70/S6K, CG10539, dS6k, ds6k, s6k11, p70 S6K, DS6K, p70[S6kinase], p70[S6 kinase], fs(3)07084, Dp70s6k, p70s6K, dps6k, dp70s6k, 7084, p70[S6k], p70S6K, Dp70[s6k], Dp70S6k, dp70[S6k], l(3)07084, p70[S6K], 10539, S6k|S6K, 7-10, Pk?6, Pk64F, p-S6K" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR016238:Ribosomal protein S6 kinase, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal" CG10539 11-Aug-17 DroID_v2017_08 "Drer\rps6kal, Drer\sgk2a, Drer\akt2, Drer\rps6ka3a, Drer\stk32a, Drer\rps6ka4, Drer\rps6ka3b, Drer\akt3b, Drer\akt3a, Drer\rps6kb1b, Drer\sgk2b, Drer\sgk1, Drer\rps6ka2, Drer\akt2l, Drer\rps6kb1a, Drer\rps6ka1, Drer\sgk3, Drer\rps6ka5, Drer\si:ch211-195b13.1, Drer\LOC100331306" "Scer\YPK3, Scer\YPK1, Scer\SCH9, Scer\YPK2" "Cele\akt-1, Cele\akt-2, Cele\ceh-93, Cele\rskn-1, Cele\R04A9.7, Cele\sgk-1, Cele\rsks-1, Cele\F28C10.3, Cele\rskn-2" "Xtro\rps6ka1, Xtro\rps6ka2, Xtro\stk32a, Xtro\sgk2, Xtro\sgk1, Xtro\rps6ka4, Xtro\rps6kb1, Xtro\rps6ka6, Xtro\akt1, Xtro\akt2, Xtro\rps6ka3" "Mmus\Rps6ka3, Mmus\Sgk1, Mmus\Stk32b, Mmus\Rps6kb1, Mmus\Rps6ka4, Mmus\Rps6kb2, Mmus\Rps6ka5, Mmus\Rps6ka1, Mmus\Rps6ka6, Mmus\Sgk3, Mmus\Akt3, Mmus\Stk32c, Mmus\Sgk2, Mmus\Akt2, Mmus\Rps6ka2, Mmus\Akt1, Mmus\Stk32a" "Hsap\STK32B, Hsap\RPS6KA3, Hsap\AKT2, Hsap\RPS6KA1, Hsap\RPS6KA6, Hsap\RPS6KB1, Hsap\RPS6KB2, Hsap\SGK2, Hsap\AKT3, Hsap\AKT1, Hsap\STK32A, Hsap\RPS6KA2, Hsap\SGK1, Hsap\SGK3, Hsap\STK32C, Hsap\RPS6KA5, Hsap\RPS6KA4" "viable,small body,visible,neurophysiology defective,partially lethal - majority die,recessive,female sterile,lethal,partially,decreased cell size,lethal - all die before end of larval stage,some die during larval stage,size defective,decreased cell number,wild-type,cell autonomous,somatic clone,neuroanatomy defective,feeding behavior defective,long lived,increased cell number,increased cell size,large body,increased cell growth,chemical resistant,short lived,memory defective,heat sensitive" "segment border muscle,A1-7 dorsal acute muscle 1,embryonic/larval somatic muscle,embryonic myoblast,wing,oocyte,adult,wing & cell | somatic clone,ommatidium,somatic clone,cell | adult stage,wing & cell,wing disc,mitotic cell cycle | somatic clone,eye,larval salivary gland & nucleus,dendrite | somatic clone,dendritic arborizing neuron,embryonic/larval fat body,NMJ bouton,wing blade,salivary gland,trichogen cell" DRSC11276 I -1.527743561 2.457851183 -0.911281262 -1.151322699 0.056746863 0.686103813 FBgn0053866 His3:CG33866 His3:CG33866 http://flybase.org/reports/FBgn0053866 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33866, His3:CG33866, His3" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33866 11-Aug-17 DroID_v2017_08 "Drer\h3f3b.1, Drer\hist2h3ca1, Drer\si:dkey-108k21.25, Drer\zgc:113983, Drer\si:ch1073-429i10.3, Drer\cenpa, Drer\h3f3c, Drer\hist2h3c, Drer\LOC108190747, Drer\zgc:113984, Drer\LOC108190746, Drer\zgc:173552, Drer\si:ch73-36p18.2, Drer\h3f3d, Drer\h3f3a" "Scer\CSE4, Scer\HHT2, Scer\HHT1" "Cele\his-74, Cele\his-59, Cele\his-13, Cele\his-9, Cele\his-69, Cele\his-40, Cele\his-25, Cele\his-63, Cele\his-27, Cele\his-72, Cele\his-45, Cele\his-17, Cele\his-71, Cele\his-6, Cele\his-2, Cele\his-32, Cele\his-55, Cele\his-42, Cele\his-49" "Xtro\hist2h3d, Xtro\LOC100486113, Xtro\hist2h3c, Xtro\cenpa, Xtro\h3f3b" "Mmus\Hist1h3g, Mmus\Hist2h3c2, Mmus\Hist1h3d, Mmus\Hist1h3b, Mmus\Hist1h3f, Mmus\H3f3b, Mmus\Cenpa, Mmus\Hist2h3b, Mmus\Hist1h3h, Mmus\Hist1h3a, Mmus\Hist1h3i, Mmus\Hist1h3e, Mmus\H3f3a, Mmus\Hist1h3c, Mmus\Hist2h3c1, Mmus\Hist2h2be" "Hsap\H3F3C, Hsap\HIST2H3C, Hsap\HIST1H3B, Hsap\HIST1H3J, Hsap\HIST1H3D, Hsap\HIST2H3A, Hsap\HIST1H3F, Hsap\HIST3H3, Hsap\H3F3B, Hsap\HIST1H3C, Hsap\HIST1H3I, Hsap\H3F3A, Hsap\HIST1H3G, Hsap\CENPA, Hsap\HIST1H3E, Hsap\HIST1H3H, Hsap\HIST1H3A, Hsap\HIST2H3D" FBgn0265726 Nna1 Nna1 carboxypeptidase http://flybase.org/reports/FBgn0265726 protein_coding_gene metallocarboxypeptidase activity ; GO:0004181 | inferred from electronic annotation with InterPro:IPR000834 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype larval development ; GO:0002164 | inferred from mutant phenotype neural retina development ; GO:0003407 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "CG44533, CG11428, CG32627, CG32628, NnaD, Nna1" "IPR000834:Peptidase M14, carboxypeptidase A" CG44533 11-Aug-17 DroID_v2017_08 "Drer\tpst1l, Drer\tpst1, Drer\agbl2, Drer\agtpbp1, Drer\agbl5" - "Cele\tpst-1, Cele\ccpp-1" "Xtro\agtpbp1, Xtro\agbl2, Xtro\agbl1, Xtro\agbl5" "Mmus\Agtpbp1, Mmus\Agbl1, Mmus\Agbl3, Mmus\Agbl4, Mmus\Tpst1, Mmus\Tpst2, Mmus\Agbl2, Mmus\Agbl5" "Hsap\AGBL3, Hsap\AGBL5, Hsap\AGBL2, Hsap\AGTPBP1, Hsap\AGBL1, Hsap\AGBL4, Hsap\TPST2, Hsap\TPST1" DRSC19404 K -0.17179376 0.465275645 -0.257684559 0.76096315 2.386751242 -0.25729871 FBgn0032162 CG4592 - http://flybase.org/reports/FBgn0032162 protein_coding_gene enoyl-CoA hydratase activity ; GO:0004300 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000941570 CG4592 "IPR001753:Crotonase superfamily, IPR029045:ClpP/crotonase-like domain" CG4592 11-Aug-17 DroID_v2017_08 Drer\eci1 - - Xtro\eci1 Mmus\Eci1 Hsap\ECI1 viable FBgn0003124 polo polo http://flybase.org/reports/FBgn0003124 "FBgn0010758, FBgn0016019, FBgn0027987, FBgn0028177, FBgn0046400" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with gwl" meiotic spindle midzone assembly ; GO:0051257 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype protein localization ; GO:0008104 | non-traceable author statement oocyte fate commitment ; GO:0048600 | inferred from mutant phenotype sperm aster formation ; GO:0035044 | inferred from mutant phenotype pronuclear migration ; GO:0035046 | inferred from mutant phenotype pronuclear fusion ; GO:0007344 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype inferred from genetic interaction with Map205 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay male meiosis ; GO:0007140 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype cellular protein localization ; GO:0034613 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype spindle assembly involved in female meiosis II ; GO:0007058 | inferred from mutant phenotype male germline ring canal formation ; GO:0030726 | inferred from mutant phenotype attachment of mitotic spindle microtubules to kinetochore ; GO:0051315 | inferred from direct assay astral microtubule nucleation ; GO:0030954 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype female meiosis II ; GO:0007147 | inferred from mutant phenotype midbody ; GO:0030496 | inferred from direct assay spindle pole ; GO:0000922 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay mitotic spindle midzone ; GO:1990023 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay condensed chromosome outer kinetochore ; GO:0000940 | inferred from direct assay condensed chromosome outer kinetochore ; GO:0000940 | non-traceable author statement spindle ; GO:0005819 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay centrosome ; GO:0005813 | kinetochore ; GO:0000776 | "polo, Polo, POLO, POLO/PLK1, CG12306, l(3)01673, 1324/08, 0256/04, l(3)77Aa, l(3)S132408, l(3)S025604, anon-WO0172774.3, Polo kinase, PLK1" "IPR000719:Protein kinase domain, IPR000959:POLO box domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR033695:Second polo-box domain, IPR033701:First polo-box domain" CG12306 11-Aug-17 DroID_v2017_08 "Drer\plk2b, Drer\plk1, Drer\plk3, Drer\plk2a, Drer\plk4" Scer\CDC5 "Cele\plk-1, Cele\plk-3, Cele\plk-2" "Xtro\plk2, Xtro\plk1, Xtro\plk3, Xtro\plk4" "Mmus\Plk1, Mmus\Plk5, Mmus\Plk3, Mmus\Plk2, Mmus\Plk4" "Hsap\PLK1, Hsap\PLK2, Hsap\PLK3, Hsap\PLK4" " larval stage && spermatogenesis , embryonic stage -- adult stage , larval stage , embryonic stage | stage 4 , embryonic stage | blastoderm " " testis

, ventral nerve cord

, imaginal disc

, organism | ubiquitous

, larval optic lobe

, larval brain

" embryonic stage "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,hyperplasia,neuroanatomy defective,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,viable,sterile,somatic clone,cytokinesis defective,some die during third instar larval stage,female sterile,wild-type,male,meiotic cell cycle defective,female,reduced,cell cycle defective,partially lethal - majority die,partially lethal,maternal effect,some die during embryonic stage,lethal - all die before end of embryonic stage,dominant,visible" "neuroblast & centrosome & larva,testis,primary spermatocyte cyst,onion stage spermatid,Nebenkern,meiotic cell cycle & spindle | male,mitotic cell cycle,mitosis & nuclear chromosome,nuclear chromosome,aster,embryonic/larval cardial cell,neuroblast & larval brain,neuroblast & larval brain | somatic clone,spindle & neuroblast,germarium region 2a,synaptonemal complex,germarium region 3,adult abdomen,tergite,embryonic/larval neuroblast,embryonic/larval brain,macrochaeta,abdomen,germline cyst,meiotic cell cycle | female,polar body nucleus,spermatocyte & spindle,spermatocyte & pericentriolar material,spermatocyte & midbody,spermatid,neuroblast & mitotic anaphase & larva,meiosis II | female,meiotic metaphase II & spindle | female,meiosis II & aster | female,meiosis II & spindle | female,male pronucleus,female pronucleus,meiotic telophase II & contractile ring | female,spindle,centrosome,adult cuticle,germarium region 2b,germarium,type II neuroblast,somatic clone,supernumerary,egg,centrosome | embryonic stage 4,centrosome | embryonic stage 4 | maternal effect,ganglion mother cell,mesothoracic tergum" DRSC22359 EK 1.182863402 0.84616027 -0.441853429 -2.231780857 2.168500088 1.684353783 FBgn0053809 His3:CG33809 His3:CG33809 http://flybase.org/reports/FBgn0053809 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33809, His3:CG33809" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33809 11-Aug-17 DroID_v2017_08 "Drer\hist2h3ca1, Drer\h3f3b.1, Drer\h3f3a, Drer\zgc:113984, Drer\LOC108190746, Drer\hist2h3c, Drer\cenpa, Drer\LOC108190747, Drer\h3f3d, Drer\si:ch73-36p18.2, Drer\zgc:113983, Drer\zgc:173552, Drer\h3f3c, Drer\si:ch1073-429i10.3" "Scer\HHT1, Scer\HHT2, Scer\CSE4" "Cele\his-49, Cele\his-45, Cele\his-17, Cele\his-59, Cele\his-42, Cele\his-71, Cele\his-27, Cele\his-69, Cele\his-9, Cele\his-55, Cele\his-74, Cele\his-13, Cele\his-2, Cele\his-32, Cele\his-25, Cele\his-6, Cele\his-72, Cele\his-63" "Xtro\cenpa, Xtro\h3f3b, Xtro\hist2h3d" "Mmus\Hist1h3c, Mmus\Hist1h3i, Mmus\H3f3a, Mmus\H3f3b, Mmus\Hist1h3h, Mmus\Cenpa, Mmus\Hist1h3g, Mmus\Hist1h3a, Mmus\Hist1h3b, Mmus\Hist2h3c2, Mmus\Hist1h3e, Mmus\Hist1h3f, Mmus\Hist1h3d, Mmus\Hist2h3b, Mmus\Hist2h3c1" "Hsap\HIST1H3B, Hsap\HIST1H3E, Hsap\HIST1H3I, Hsap\HIST1H3F, Hsap\HIST1H3J, Hsap\CENPA, Hsap\HIST2H3D, Hsap\HIST1H3A, Hsap\HIST3H3, Hsap\HIST1H3D, Hsap\H3F3A, Hsap\H3F3C, Hsap\HIST1H3G, Hsap\HIST1H3C, Hsap\H3F3B, Hsap\HIST2H3A, Hsap\HIST1H3H, Hsap\HIST2H3C" FBgn0053880 His2B:CG33880 His2B:CG33880 http://flybase.org/reports/FBgn0053880 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33880, His2B:CG33880" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33880 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.27, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.1, Drer\zgc:92591, Drer\zgc:173585, Drer\hist1h2ba, Drer\si:dkey-23a13.5, Drer\si:ch73-368j24.8, Drer\si:ch1073-153i20.3, Drer\ano9a, Drer\si:dkey-23a13.16, Drer\zgc:173587, Drer\si:dkey-261m9.19, Drer\si:ch1073-159d7.13, Drer\LOC100334869, Drer\si:ch73-36p18.3, Drer\hist2h2l, Drer\LOC100334559, Drer\zgc:194989, Drer\zgc:114046, Drer\si:ch1073-159d7.5, Drer\si:ch211-113a14.29, Drer\LOC100329560, Drer\si:dkey-108k21.11, Drer\LOC100329290, Drer\si:dkey-261m9.6, Drer\si:ch211-113a14.28" "Scer\HTB2, Scer\HTB1" "Cele\his-11, Cele\his-41, Cele\his-66, Cele\his-8, Cele\his-22, Cele\his-15, Cele\his-44, Cele\his-54, Cele\his-39, Cele\his-52, Cele\his-20, Cele\his-34, Cele\his-58, Cele\his-4, Cele\his-62, Cele\his-48, Cele\his-29" "Xtro\LOC101734494, Xtro\LOC100485294, Xtro\LOC100498647, Xtro\LOC101731959, Xtro\LOC100496181, Xtro\LOC100498072, Xtro\hist1h2bm, Xtro\LOC101733489, Xtro\LOC100498553, Xtro\hist1h2bk, Xtro\LOC100495041, Xtro\LOC100495396, Xtro\LOC100495578, Xtro\LOC101731067, Xtro\LOC100485134, Xtro\LOC100498329, Xtro\LOC101734862, Xtro\LOC100496445, Xtro\hist1h2bj, Xtro\LOC100486150, Xtro\LOC101735218, Xtro\LOC100495415, Xtro\hist2h2be, Xtro\LOC101730940, Xtro\LOC100496436, Xtro\LOC100497915, Xtro\LOC101733171, Xtro\LOC101735164, Xtro\LOC100492632, Xtro\LOC100486870, Xtro\LOC101733828, Xtro\LOC101731852, Xtro\LOC100497082, Xtro\LOC100487485" "Mmus\Hist2h2be, Mmus\Hist1h2bp, Mmus\Hist1h2bb, Mmus\Hist1h2be, Mmus\Hist3h2ba, Mmus\1700024P04Rik, Mmus\Hist1h2bl, Mmus\Hist1h2bq, Mmus\Hist1h2bk, Mmus\Hist1h2bj, Mmus\Hist2h2bb, Mmus\Hist1h2bm, Mmus\Hist1h2ba, Mmus\Hist1h2bn, Mmus\H2bfm, Mmus\Hist1h2bf, Mmus\Hist1h2bh, Mmus\Hist1h2bc, Mmus\Hist1h2br, Mmus\Hist1h2bg" "Hsap\HIST1H2BM, Hsap\HIST1H2BL, Hsap\HIST2H2BF, Hsap\HIST1H2BC, Hsap\HIST1H2BK, Hsap\H2BFWT, Hsap\HIST1H2BO, Hsap\HIST1H2BA, Hsap\HIST1H2BF, Hsap\H2BFM, Hsap\HIST1H2BH, Hsap\HIST1H2BB, Hsap\HIST1H2BN, Hsap\HIST1H2BJ, Hsap\HIST1H2BG, Hsap\HIST3H2BB, Hsap\HIST1H2BI, Hsap\HIST1H2BE, Hsap\HIST1H2BD, Hsap\HIST2H2BE" FBgn0041188 Atx2 Ataxin-2 http://flybase.org/reports/FBgn0041188 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with tyf short-term memory ; GO:0007614 | NOT inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype positive regulation of neuron death ; GO:1901216 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype circadian regulation of translation ; GO:0097167 | inferred from mutant phenotype inferred from physical interaction with tyf oocyte differentiation ; GO:0009994 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype positive regulation of protein binding ; GO:0032092 | inferred from mutant phenotype regulation of synapse structural plasticity ; GO:0051823 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of cytoplasmic mRNA processing body assembly ; GO:0010603 | inferred from biological aspect of ancestor with PANTHER:PTN000304339 circadian regulation of translation ; GO:0097167 | inferred from genetic interaction with per inferred from genetic interaction with tyf compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype stress granule assembly ; GO:0034063 | inferred from biological aspect of ancestor with PANTHER:PTN000304339 negative regulation of gene silencing by miRNA ; GO:0060965 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype cytoplasmic stress granule ; GO:0010494 | inferred from biological aspect of ancestor with PANTHER:PTN000304339 cytoplasm ; GO:0005737 | inferred from direct assay "dAtx2, CG5166, SCA2, Datx2, GH27029, dSCA2, Sca2, l(3)06490, atx2, anon-EST:fe2E1, BEST:GH27029, anon-WO0140519.1, anon-WO0118547.351, Atx2, CG5166a, ATX2, Atxain-2, Atx-2, atx-2" "IPR009604:LsmAD domain, IPR025852:Ataxin 2, SM domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR009818:Ataxin-2, C-terminal" CG5166 11-Aug-17 DroID_v2017_08 "Drer\atxn2l, Drer\atxn2" "Scer\PBP1, Scer\AIM3" Cele\atx-2 "Xtro\atxn2l, Xtro\atxn2" "Mmus\Atxn2l, Mmus\Maml1, Mmus\Atxn2" "Hsap\ATXN2L, Hsap\ATXN2" "viable,lethal,recessive,visible,somatic clone,female sterile,germline clone,lethal - all die before end of larval stage,some die during larval stage,increased cell death,uncoordinated,partially lethal - majority die,decreased cell number,conditional,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,circadian behavior defective,learning defective,heat sensitive,locomotor rhythm defective" "eye,somatic clone,ommatidium,nurse cell,germline clone,oocyte,nurse cell & nucleus | germ-line clone,nurse cell & actin filament | germ-line clone,retina,eye disc,border follicle cell,adult thorax & chaeta, with Atx2UAS.cSa, [-],adult thorax & chaeta, with Atx2X1, [-],head,photoreceptor,conditional,embryonic/larval neuroblast" DRSC23010 K -0.179759034 1.948302039 FBgn0000257 car carnation http://flybase.org/reports/FBgn0000257 "FBgn0027357, FBgn0040160" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24314 syntaxin binding ; GO:0019905 | inferred from physical interaction with Syx16 syntaxin binding ; GO:0019905 | contributes_to inferred from physical interaction with Syx17 SNARE binding ; GO:0000149 | inferred from sequence or structural similarity vesicle docking involved in exocytosis ; GO:0006904 | inferred from electronic annotation with InterPro:IPR001619 endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000004388 protein targeting to lysosome ; GO:0006622 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | traceable author statement compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype endosome organization ; GO:0007032 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | inferred from genetic interaction with p autophagosome maturation ; GO:0097352 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with l(2)gd1 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype regulation of protein ubiquitination ; GO:0031396 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | traceable author statement endocytosis ; GO:0006897 | inferred from mutant phenotype intracellular transport ; GO:0046907 | traceable author statement Notch receptor processing ; GO:0007220 | inferred from mutant phenotype regulation of SNARE complex assembly ; GO:0035542 | inferred from sequence or structural similarity with SGD:S000004388 membrane ; GO:0016020 | traceable author statement cytosol ; GO:0005829 | traceable author statement CORVET complex ; GO:0033263 | inferred from sequence or structural similarity with SGD:S000004388 HOPS complex ; GO:0030897 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay HOPS complex ; GO:0030897 | inferred from mutant phenotype HOPS complex ; GO:0030897 | inferred from sequence or structural similarity with SGD:S000004388 "car, Vps33/carnation, Vps33p, Vps33, Dm-Vps33, l(1)G0447, CG12230, carn, VPS33a, Vps33a, Vps33A, Car" "IPR001619:Sec1-like protein, IPR027121:Vacuolar protein sorting-associated protein 33" CG12230 11-Aug-17 DroID_v2017_08 "Drer\vps33a, Drer\vps33b" Scer\VPS33 "Cele\vps-33.2, Cele\vps-33.1" "Xtro\vps33b, Xtro\vps33a" "Mmus\Vps33a, Mmus\Vps33b" "Hsap\VPS33B, Hsap\VPS33A" "viable,fertile,partially lethal - majority die,recessive,visible,short lived,male,eye color defective,decreased cell death,wild-type,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,some die during pupal stage,lethal - all die before end of pupal stage" "eye,late endosome,pigment cell,Malpighian tubule,embryonic/larval brain,endosome,ommatidium,rhabdomere,spermatogonial cyst,male germline cell,somatic clone,rhabdomere | cell autonomous | somatic clone,wing,mesothoracic tergum,embryonic/larval fat body,nutrition conditional,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0015247 Diap2 Death-associated inhibitor of apoptosis 2 http://flybase.org/reports/FBgn0015247 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 cysteine-type endopeptidase inhibitor activity involved in apoptotic process ; GO:0043027 | inferred from direct assay ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay caspase binding ; GO:0089720 | inferred from physical interaction with Drice zinc ion binding ; GO:0008270 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with rpr ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Diap1 "negative regulation of apoptotic process ; GO:0043066 | inferred from direct assay positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043281 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | traceable author statement peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043154 | inferred from genetic interaction with Drice sensory organ development ; GO:0007423 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype protein K48-linked ubiquitination ; GO:0070936 | inferred from direct assay positive regulation of protein import into nucleus, translocation ; GO:0033160 | inferred from mutant phenotype protein K63-linked ubiquitination ; GO:0070534 | inferred from direct assay inhibition of cysteine-type endopeptidase activity involved in apoptotic process ; GO:1990001 | inferred from biological aspect of ancestor with PANTHER:PTN000799330 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity regulation of signal transduction ; GO:0009966 | inferred from biological aspect of ancestor with PANTHER:PTN000005165 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043154 | inferred from direct assay protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000799330 perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "CG8293, DIAP2, DIAPII, diap2, Diap2, DIAP-2, DIAP, dIAP2, IAP, dIAP, DIHA, D-IAP2, dILP, D-iap2, Ilp, Diha, Diap, IAP2, Iap2, Diap-2" "IPR001370:BIR repeat, IPR001841:Zinc finger, RING-type" CG8293 11-Aug-17 DroID_v2017_08 "Drer\mylipb, Drer\birc7, Drer\birc5b, Drer\birc5a, Drer\birc6, Drer\xiap, Drer\birc2" Scer\BIR1 "Cele\K11D12.9, Cele\bir-1, Cele\bir-2" "Xtro\birc2, Xtro\birc7, Xtro\birc5.2, Xtro\xiap, Xtro\nlrc4, Xtro\birc5.1, Xtro\birc6" "Mmus\Naip2, Mmus\Birc7, Mmus\Nlrc4, Mmus\Naip1, Mmus\Birc6, Mmus\Birc5, Mmus\Xiap, Mmus\Birc2, Mmus\Naip6, Mmus\Naip7, Mmus\Naip5, Mmus\Birc3" "Hsap\NAIP, Hsap\XIAP, Hsap\BIRC8, Hsap\BIRC7, Hsap\BIRC3, Hsap\BIRC5, Hsap\MYLIP, Hsap\NLRC4, Hsap\BIRC2, Hsap\BIRC6" embryonic stage&&larval stage&&adult stage "lethal - all die before end of pupal stage,some die during pupal stage,immune response defective,visible,body color defective,partially lethal - majority die,viable,radiation sensitive,cell death defective,conditional,fertile,increased cell death,chemical sensitive" "macrochaeta,supernumerary,trichogen cell,mesothoracic tergum,wing disc,eye,pigment cell" FBgn0265434 zip zipper http://flybase.org/reports/FBgn0265434 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR004009 myosin light chain binding ; GO:0032027 | inferred from physical interaction with sqh inferred from physical interaction with Mlc-c motor activity ; GO:0003774 | inferred from sequence or structural similarity with SGD:S000001065 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" "mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement muscle attachment ; GO:0016203 | NOT inferred from genetic interaction with l(2)gl dorsal closure ; GO:0007391 | inferred from genetic interaction with cno, PDZ-GEF maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype myosin II filament assembly ; GO:0031036 | inferred from direct assay establishment of neuroblast polarity ; GO:0045200 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype anterior midgut development ; GO:0007496 | inferred from mutant phenotype protein oligomerization ; GO:0051259 | inferred from direct assay sarcomere organization ; GO:0045214 | inferred from mutant phenotype ovarian follicle cell migration ; GO:0007297 | traceable author statement dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype left/right axis specification ; GO:0070986 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with dsh inferred from genetic interaction with fz muscle contraction ; GO:0006936 | inferred from mutant phenotype dorsal closure, leading edge cell differentiation ; GO:0046663 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | non-traceable author statement cellular response to mechanical stimulus ; GO:0071260 | inferred from direct assay regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from direct assay regulation of myoblast fusion ; GO:1901739 | inferred from genetic interaction with kirre salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype" cell-cell contact zone ; GO:0044291 | inferred from direct assay apical cortex ; GO:0045179 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cell cortex ; GO:0005938 | inferred from mutant phenotype apical cortex ; GO:0045179 | traceable author statement cell leading edge ; GO:0031252 | inferred from direct assay myosin II complex ; GO:0016460 | inferred from physical interaction with sqh inferred from physical interaction with Mlc-c cytosol ; GO:0005829 | inferred from direct assay contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay unconventional myosin complex ; GO:0016461 | inferred from sequence or structural similarity myosin complex ; GO:0016459 | inferred from sequence or structural similarity myosin II complex ; GO:0016460 | inferred from direct assay cytoskeleton ; GO:0005856 | non-traceable author statement Z disc ; GO:0030018 | inferred from direct assay unconventional myosin complex ; GO:0016461 | non-traceable author statement "zip, Zip, CG15792, MyoII, zipper, NMM, Myo-II, myoII, nmMHC, Dm nmII, DmnmII, Myo, nmy-2, E(br), DROMHC, l(2)02957, Dronm-MII, Mhc-c, zpr, anon-WO0140519.37, Mhc-c[1], Myo II, MHC, zip/MyoII, NMMII, Myo-II HC, Myo2, ZIP, l(2)17F1, myo II, Myo15, myosin-II" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site, IPR001609:Myosin head, motor domain, IPR002928:Myosin tail, IPR004009:Myosin, N-terminal, SH3-like" CG15792 11-Aug-17 DroID_v2017_08 "Drer\myo5aa, Drer\myo18aa, Drer\LOC103909185, Drer\smyhc2, Drer\myh10, Drer\LOC100537963, Drer\LOC100329748, Drer\wu:fd14a01, Drer\myhb, Drer\myhz1.2, Drer\myh6, Drer\myo5c, Drer\myh11a, Drer\myo5b, Drer\myhz1.1, Drer\ns:zf-e68, Drer\smyhc3, Drer\LOC100333206, Drer\si:dkey-110c1.10, Drer\myhz2, Drer\myh7bb, Drer\LOC100329813, Drer\myh9a, Drer\smyhc1, Drer\myo18ab, Drer\myha, Drer\LOC100333572, Drer\LOC100331349, Drer\myh11b, Drer\vmhc, Drer\myhc4, Drer\myo5ab, Drer\vmhcl, Drer\myh7ba, Drer\myh14, Drer\myh9b" "Scer\MYO4, Scer\MYO1, Scer\MYO2" "Cele\hum-9, Cele\nmy-1, Cele\myo-5, Cele\syd-2, Cele\myo-3, Cele\unc-54, Cele\unc-15, Cele\nmy-2, Cele\myo-2, Cele\myo-6, Cele\myo-1, Cele\hum-2" "Xtro\myh9, Xtro\myo5b, Xtro\myh4, Xtro\myh6, Xtro\myo5a, Xtro\myo18b, Xtro\myh8, Xtro\LOC100493774, Xtro\myh13, Xtro\myh15, Xtro\myh2, Xtro\myh11" "Mmus\Myo18a, Mmus\Myh11, Mmus\Myh14, Mmus\Myh7, Mmus\Myo5b, Mmus\Myh6, Mmus\Myh13, Mmus\Myh7b, Mmus\Myh15, Mmus\Myh8, Mmus\Myh9, Mmus\Myh2, Mmus\Myh1, Mmus\Myh10, Mmus\Myh4, Mmus\Myo5c, Mmus\Myo18b, Mmus\Myh3, Mmus\Myo5a" "Hsap\MYH2, Hsap\MYO5A, Hsap\MYO18A, Hsap\MYH9, Hsap\MYH1, Hsap\MYH15, Hsap\MYH10, Hsap\MYO5C, Hsap\MYO18B, Hsap\MYH11, Hsap\MYH7, Hsap\MYH4, Hsap\MYH8, Hsap\MYH3, Hsap\MYO5B, Hsap\MYH6, Hsap\MYH7B, Hsap\MYH14, Hsap\MYH13" " embryonic stage , embryonic stage && adult stage , embryonic stage | stage 8 " " embryonic central nervous system

, mesoderm

" FBgn0020299 stumps stumps http://flybase.org/reports/FBgn0020299 "FBgn0024898, FBgn0025779, FBgn0028088, FBgn0038245, FBgn0051317, FBgn0063634" protein_coding_gene - "open tracheal system development ; GO:0007424 | non-traceable author statement mesodermal cell migration ; GO:0008078 | traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | non-traceable author statement gastrulation ; GO:0007369 | non-traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | non-traceable author statement heart development ; GO:0007507 | non-traceable author statement mesoderm development ; GO:0007498 | inferred from expression pattern tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype morphogenesis of a branching structure ; GO:0001763 | non-traceable author statement glial cell development ; GO:0021782 | inferred from mutant phenotype" intracellular ; GO:0005622 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement cytoplasm ; GO:0005737 | non-traceable author statement "stumps, Hbr, hbr, Dof, CG18485, dof, DOF, dof/hbr/sms, i21, i28, CG3375, Hbr/Dof, stumps/dof, Dof/stumps/heartbroken, dof/hbr, l(3)09904, heartbroken/dof, sms, gene C, P1740, 0837/10, C, l(3)S083710, anon-estC, anon-EST:CL47, CG31317, dof1" "IPR017893:DBB domain, IPR020683:Ankyrin repeat-containing domain" CG31317 11-Aug-17 DroID_v2017_08 Drer\pik3ap1 - - Xtro\pik3ap1 "Mmus\Bank1, Mmus\Pik3ap1" "Hsap\BANK1, Hsap\PIK3AP1" " embryonic stage | stage 11 , embryonic stage , embryonic stage | stage >=11 , embryonic stage | stage 9,10 , embryonic stage | stage >5 , embryonic stage | stage 13 , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | syncytial blastoderm , embryonic stage | stage 11-12 " " tracheal pit

, embryonic/larval heart

, embryonic/larval tracheal system

, tracheal primordium

, mesoderm

, visceral mesoderm

, mesoderm anlage

, posterior midgut proper primordium

, anterior midgut proper primordium

,

ventral , embryonic glial cell

" " embryonic stage | stage 11 , larval stage | third instar , embryonic stage | stage <11 " " tracheal pit

, mesoderm

dorsal & restricted , dorsal mesothoracic disc && adepithelial cell

, mesoderm

" "lethal,recessive,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,cell migration defective,somatic clone,viable" "embryonic/larval trachea,pericardial cell primordium,terminal tracheal cell,somatic clone,embryonic/larval tracheal system,presumptive embryonic salivary gland,tracheal system,embryonic/larval somatic muscle,dorsal,embryonic/larval pericardial cell,cardioblast,somatic mesoderm,visceral mesoderm,mesoderm,egg,presumptive embryonic/larval central nervous system,longitudinal connective,embryonic/larval dorsal vessel,midgut constriction 2,trachea,dorsal vessel primordium,embryonic pericardial cell,dorsal air sac primordium,embryonic/larval dorsal branch,glial cell,subretinal glial cell,somatic clone | third instar larval stage" DRSC15332 E 0.898952777 -1.395533715 0.51074249 -1.595115772 0.081020658 0.982072361 FBgn0004177 mts microtubule star http://flybase.org/reports/FBgn0004177 "FBgn0010514, FBgn0010703, FBgn0031953" protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from mutant phenotype protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity phosphatase regulator activity ; GO:0019208 | inferred from direct assay centrosome duplication ; GO:0051298 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from genetic interaction with inaC regulation of cell shape ; GO:0008360 | inferred from mutant phenotype centrosome cycle ; GO:0007098 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from mutant phenotype positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from genetic interaction with smo inferred from genetic interaction with hh actin filament organization ; GO:0007015 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with l(2)gl inferred from genetic interaction with par-6 spindle organization ; GO:0007051 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype canonical Wnt signaling pathway ; GO:0060070 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype establishment of epithelial cell polarity ; GO:0090162 | inferred from expression pattern regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype R7 cell fate commitment ; GO:0007465 | inferred from genetic interaction with Ras85D centriole ; GO:0005814 | inferred from direct assay protein phosphatase type 2A complex ; GO:0000159 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "mts, CG7109, PP2A-C, PP2A, PP2A/MTS, PP2, DmPp2A-28D, PP2a, PP2Ac, PP2a 28D, PP2A[[C]], MTS/PP2A, dPP2A, 5559, PP2A 28D, Pp2A-28D, Pp2A, ER2-6, l(2)s5286, l(2)02496, Mts, PP2A C, PP2A[C], dPP2A-C, MTS" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG7109 11-Aug-17 DroID_v2017_08 "Drer\ppp2cb, Drer\ppp4ca, Drer\ppp6c, Drer\ppp2ca, Drer\ppp4cb, Drer\zgc:56064" "Scer\PPH22, Scer\YNL217W, Scer\SIT4, Scer\PPG1, Scer\PPH21, Scer\PPH3" "Cele\pph-4.2, Cele\pph-4.1, Cele\pph-6, Cele\pph-1, Cele\let-92" "Xtro\ppp2cb, Xtro\ppp4c, Xtro\ppp2ca, Xtro\ppp6c" "Mmus\Ppp2ca, Mmus\Ppp6c, Mmus\Ppp4c, Mmus\Ppp2cb" "Hsap\PPP2CB, Hsap\PPP2CA, Hsap\PPP6C" " embryonic stage | early , embryonic stage | late , larval stage | third instar , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage && larval stage , embryonic stage , adult stage , embryonic stage | stage 9-11 , embryonic stage && larval stage && adult stage " " gonad

, embryonic/larval salivary gland

, imaginal disc

, supraesophageal ganglion

, nurse cell

,

ubiquitous , larval brain

, adult brain

, oocyte

, adult midgut

, neuroblast

, ventral nerve cord

" "visible,viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,neuroanatomy defective,planar polarity defective,locomotor rhythm defective,increased cell number,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone" "eye,embryonic/larval hemocyte | third instar larval stage,neuroblast,supernumerary,embryonic/larval brain,wing hair,microtubule & neuromuscular junction | larval stageelav.PLu,bouton & neuromuscular junction | larval stageelav.PLu,embryonic/larval neuroblast,wing margin,type II neuroblast,somatic clone" DRSC03574 IE 0.918009972 -3.40249302 0.404905368 -3.907711575 1.051818802 -0.556150787 FBgn0015777 nrv2 nervana 2 http://flybase.org/reports/FBgn0015777 "FBgn0014867, FBgn0021885, FBgn0022206, FBgn0045319, FBgn0065838" protein_coding_gene sodium:potassium-exchanging ATPase activity ; GO:0005391 | contributes_to inferred from mutant phenotype cation transmembrane transporter activity ; GO:0008324 | contributes_to inferred from direct assay "potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR000402 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR000402 cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from direct assay regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype" sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred from electronic annotation with InterPro:IPR000402 septate junction ; GO:0005918 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred by curator from GO:0005391 axon ; GO:0030424 | inferred from direct assay "Na[+]/K[+] ATPase, Nrv2, NaK ATPase, Na,K-ATPase, Na[+]/K[+]ATPase, Na[+]/K[+]-ATPase, 42kDa, l(2)k04223, l(2)k13315, l(2)SH0329, ecta, NEST:bs13c10, Nrv, CG9261, nrv2, l(2)SH2 0329, nrv2.2, Nrv2.2" IPR000402:Sodium/potassium-transporting ATPase subunit beta CG9261 11-Aug-17 DroID_v2017_08 "Drer\atp1b3a, Drer\atp1b2b, Drer\atp1b2a, Drer\atp1b1a, Drer\atp1b1b, Drer\atp1b3b, Drer\atp1b4" - "Cele\nkb-1, Cele\nkb-3, Cele\nkb-2" "Xtro\atp4b, Xtro\atp1b3, Xtro\atp1b4, Xtro\atp1b2, Xtro\atp1b1" "Mmus\Atp4b, Mmus\Atp1b4, Mmus\Atp1b1, Mmus\Atp1b3, Mmus\Atp1b2" "Hsap\ATP1B3, Hsap\ATP4B, Hsap\ATP1B2, Hsap\ATP1B4, Hsap\ATP1B1" adult stage "

, adult abdomen

, abdomen

, adult head

" " embryonic stage , adult stage , embryonic stage -- adult stage " " embryonic peripheral nervous system

, adult abdomen

, leg

, head

, longitudinal connective

, commissure

, central nervous system

, adult head

, adult brain

, embryonic/larval garland cell

, adult thorax

, embryonic/larval posterior spiracle

, thoracico-abdominal ganglion

, optic lobe

" "lethal,recessive,neuroanatomy defective,viable,visible,auditory perception defective" "septate junction,embryonic/larval dorsal trunk,embryonic/larval transverse connective,embryonic/larval tracheal system,embryonic ganglionic branch & embryonic tracheole,septate junction & embryonic tracheal system,ganglionic branch primordium,dorsal trunk primordium,presumptive embryonic salivary gland,embryonic somatic muscle,tracheal branch primordium,trichogen cell,Johnston organ" FBgn0000769 fs(1)A1059 female sterile (1) A1059 http://flybase.org/reports/FBgn0000769 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)M60, fs(1)1059, fs(1)K575[ts], fs(1)K575, fs(1)A1059" - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,heat sensitive" FBgn0053814 His2A:CG33814 His2A:CG33814 http://flybase.org/reports/FBgn0053814 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33814, His2A:CG33814" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33814 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-159d7.11, Drer\si:ch73-368j24.13, Drer\h2afy2, Drer\zgc:101846, Drer\si:ch211-113a14.16, Drer\si:dkey-261m9.11, Drer\si:dkey-23a13.20, Drer\si:ch211-113a14.26, Drer\si:ch1073-159d7.10, Drer\si:ch73-368j24.14, Drer\si:dkey-261m9.18, Drer\h2afx, Drer\si:ch211-113a14.7, Drer\zgc:110434, Drer\si:dkey-261m9.7, Drer\si:dkey-23a13.14, Drer\LOC100334934, Drer\si:ch211-113a14.11, Drer\LOC100332229, Drer\si:dkey-261m9.15, Drer\LOC570115, Drer\si:dkey-108k21.26, Drer\si:ch211-113a14.19, Drer\si:dkey-108k21.15, Drer\zgc:173652, Drer\si:dkey-108k21.19, Drer\si:ch73-36p18.5, Drer\zgc:195633, Drer\zgc:154164, Drer\fbxl6, Drer\LOC100148591, Drer\si:dkey-23a13.7, Drer\zgc:114037" "Scer\HTA2, Scer\HTA1" "Cele\his-65, Cele\his-68, Cele\his-35, Cele\his-47, Cele\his-61, Cele\his-7, Cele\his-33, Cele\his-57, Cele\htas-1, Cele\his-21, Cele\his-30, Cele\his-16, Cele\his-3, Cele\his-19, Cele\his-53, Cele\his-43, Cele\his-51, Cele\his-12" "Xtro\hist1h2aa, Xtro\h2afx, Xtro\hist1h2am, Xtro\h2afj, Xtro\h2afy2, Xtro\hist1h2aj, Xtro\h2afy, Xtro\hist1h2ad, Xtro\hist1h2ah" "Mmus\Hist2h2aa2, Mmus\Hist2h2ab, Mmus\Hist3h2a, Mmus\Hist1h2ao, Mmus\H2afb1, Mmus\Hist2h2ac, Mmus\Hist2h2aa1, Mmus\H2al1n, Mmus\H2afy2, Mmus\Hist1h2ai, Mmus\H2afx, Mmus\H2afb2, Mmus\Gm14920, Mmus\H2al1j, Mmus\H2al2c, Mmus\Hist1h2ak, Mmus\H2al2b, Mmus\H2afj, Mmus\Hist1h2ae, Mmus\Hist1h2ab, Mmus\Hist1h2an, Mmus\Hist1h2ah, Mmus\Hist1h2ag, Mmus\Hist1h2af, Mmus\H2afy, Mmus\Hist2h3c1, Mmus\Hist1h2ad, Mmus\Hist1h2ap, Mmus\Hist1h2ac, Mmus\H2afb3, Mmus\Hist1h2aa" "Hsap\HIST1H2AE, Hsap\HIST2H2AB, Hsap\HIST1H2AK, Hsap\HIST2H2AA3, Hsap\HIST1H2AG, Hsap\HIST1H2AJ, Hsap\H2AFB2, Hsap\HIST1H2AA, Hsap\H2AFY, Hsap\H2AFY2, Hsap\H2AFJ, Hsap\HIST1H2AI, Hsap\HIST1H2AC, Hsap\H2AFB1, Hsap\HIST1H2AH, Hsap\HIST1H2AL, Hsap\HIST1H2AM, Hsap\HIST2H2AA4, Hsap\H2AFX, Hsap\HIST3H2A, Hsap\HIST1H2AB, Hsap\HIST2H2AC, Hsap\H2AFB3, Hsap\HIST1H2AD" FBgn0085259 CG34230 - http://flybase.org/reports/FBgn0085259 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34230 - CG34230 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0065916 l(2)SH0168 lethal (2) SH0168 http://flybase.org/reports/FBgn0065916 gene - - - "l(2)SH0168, l(2)SH2 0168" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0039882 CG11576 - http://flybase.org/reports/FBgn0039882 protein_coding_gene riboflavin transporter activity ; GO:0032217 | inferred from electronic annotation with InterPro:IPR009357 riboflavin transport ; GO:0032218 | inferred from electronic annotation with InterPro:IPR009357 integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR009357 cytosol ; GO:0005829 | inferred from direct assay CG11576 "IPR009357:Solute carrier family 52, riboflavin transporter" CG11576 11-Aug-17 DroID_v2017_08 "Drer\zgc:91890, Drer\si:ch73-196l6.5, Drer\slc52a3, Drer\slc52a2" - "Cele\rft-2, Cele\rft-1" "Xtro\slc52a1, Xtro\slc52a3" "Mmus\Slc52a2, Mmus\Slc52a3" "Hsap\SLC52A3, Hsap\SLC52A2, Hsap\SLC52A1" "viable,fertile,lethal,partially lethal - majority die,some die during pupal stage" FBgn0067067 Nrt::Wnt2 Nrt::Wnt2 http://flybase.org/reports/FBgn0067067 engineered_fusion_gene - - - Nrt::Wnt2 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0003314 sam sperm amotile http://flybase.org/reports/FBgn0003314 - gene - - - sam - - 11-Aug-17 DroID_v2017_08 - - - - - - male sterile FBgn0060448 l(3)S121612 lethal (3) S121612 http://flybase.org/reports/FBgn0060448 gene - - - "1216/12, l(3)S121612" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0053905 His4:CG33905 His4:CG33905 http://flybase.org/reports/FBgn0053905 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33905, His4:CG33905" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33905 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.26, Drer\si:dkey-108k21.19, Drer\LOC100329358, Drer\si:ch73-36p18.3, Drer\zgc:153409, Drer\LOC794549, Drer\zgc:154164, Drer\si:ch73-368j24.1, Drer\LOC562770, Drer\si:dkey-108k21.28, Drer\si:dkey-261m9.17, Drer\LOC100150038, Drer\si:ch73-368j24.14, Drer\si:dkey-108k21.12, Drer\si:ch73-36p18.4, Drer\hist1h4l, Drer\LOC100331412, Drer\si:ch211-113a14.17, Drer\zgc:194989, Drer\zgc:163040, Drer\LOC570405, Drer\si:ch211-113a14.6, Drer\si:dkey-261m9.18" "Scer\HHF2, Scer\HHF1" "Cele\his-38, Cele\his-31, Cele\his-46, Cele\his-26, Cele\his-28, Cele\his-5, Cele\his-1, Cele\his-14, Cele\his-64, Cele\his-67, Cele\his-56, Cele\his-10, Cele\his-60, Cele\his-50, Cele\his-18, Cele\his-37" "Xtro\LOC100493041, Xtro\hist1h4c, Xtro\LOC101734147, Xtro\hist1h4k" "Mmus\Hist1h4h, Mmus\Hist1h4a, Mmus\Hist1h4b, Mmus\Hist1h4d, Mmus\Hist1h4n, Mmus\Hist1h4m, Mmus\Hist1h4c, Mmus\Hist1h4i, Mmus\Hist4h4, Mmus\Hist1h4k, Mmus\Hist1h4j, Mmus\Hist2h4, Mmus\Hist1h4f" "Hsap\HIST2H4B, Hsap\HIST1H4J, Hsap\HIST1H4D, Hsap\HIST1H4I, Hsap\HIST1H4B, Hsap\HIST1H4E, Hsap\HIST4H4, Hsap\HIST2H4A, Hsap\HIST1H4G, Hsap\HIST1H4H, Hsap\HIST1H4F, Hsap\HIST1H4K, Hsap\HIST1H4C, Hsap\HIST1H4L, Hsap\HIST1H4A" FBgn0264075 tgo tango http://flybase.org/reports/FBgn0264075 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with dysf myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from physical interaction with trh RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with HGNC:700 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ss transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from physical interaction with sim inferred from physical interaction with dysf inferred from physical interaction with trh protein heterodimerization activity ; GO:0046982 | traceable author statement transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with sim inferred from physical interaction with trh transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with sim inferred from physical interaction with sima transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay cellular response to insulin stimulus ; GO:0032869 | inferred from direct assay epithelial cell fate determination, open tracheal system ; GO:0007425 | non-traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay limb development ; GO:0060173 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype epithelial cell fate determination, open tracheal system ; GO:0007425 | traceable author statement brain development ; GO:0007420 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement central nervous system development ; GO:0007417 | inferred from mutant phenotype regulation of R7 cell differentiation ; GO:0045676 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay cellular response to hypoxia ; GO:0071456 | inferred from direct assay glial cell migration ; GO:0008347 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype" "transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR001067 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001067 protein complex ; GO:0043234 | inferred from physical interaction with dysf nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:700 nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0003700,GO:0043565" "tgo, Tgo, dARNT, dHIF-1beta, Arnt, ARNT, HIF-1beta, Hif1, TGO, DARNT, arnt, Tango, darnt, HIF-1, prd7, HIF1b, CG11987, dTgo, bHLHe4, jay, TGO_CYC, tgo/Arnt, HIF1B/ARNT" "IPR000014:PAS domain, IPR001067:Nuclear translocator, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR013767:PAS fold" CG11987 11-Aug-17 DroID_v2017_08 "Drer\arnt2, Drer\arnt, Drer\npas4a" - Cele\aha-1 "Xtro\arnt2, Xtro\arnt" "Mmus\Arnt, Mmus\Arnt2" "Hsap\ARNT, Hsap\ARNT2" " embryonic stage | stage 15 , embryonic stage | stage 14 , embryonic stage | <8-12 hr , embryonic stage , oogenesis stage " " embryonic peripheral nervous system

, embryonic maxillary segment

, embryonic antennal segment

, embryonic gnathal segment

, embryonic mandibular segment

, embryonic labial segment

, leg | anlagen

,

ubiquitous " " embryonic stage | stage 15 , embryonic stage | stage 14 , embryonic stage | stage 11-17 , embryonic stage , embryonic stage | stage 11 " " embryonic peripheral nervous system

, embryonic/larval tracheal system

, embryonic maxillary segment

, embryonic mandibular segment

,

ubiquitous , embryonic antennal segment

, dorsal vessel primordium

, supraesophageal ganglion

, embryonic labial segment

, tracheal pit | surrounding

, ventral nerve cord

, embryonic/larval posterior spiracle

" FBgn0086676 spin spinster http://flybase.org/reports/FBgn0086676 protein_coding_gene sphingolipid transporter activity ; GO:0046624 | inferred from biological aspect of ancestor with PANTHER:PTN001160264 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 glial cell differentiation ; GO:0010001 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype negative regulation of decapentaplegic signaling pathway ; GO:0090099 | inferred from genetic interaction with dpp inferred from genetic interaction with sax inferred from genetic interaction with tkv inferred from genetic interaction with Mad oogenesis ; GO:0048477 | inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype lysosome organization ; GO:0007040 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype larval central nervous system remodeling ; GO:0035193 | inferred from mutant phenotype regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype sphingosine-1-phosphate signaling pathway ; GO:0003376 | inferred from biological aspect of ancestor with PANTHER:PTN001160264 endocytosis ; GO:0006897 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement regulation of nurse cell apoptotic process ; GO:0045477 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype programmed cell death ; GO:0012501 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 vesicle ; GO:0031982 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN001160264 "spin, bnch, CG8428, Spin, l(2)k09905, l(2)10403, 25/11, l(2)k02511, l(2R)W5, l(2)W5" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8428 11-Aug-17 DroID_v2017_08 "Drer\spns3, Drer\spns2, Drer\spns1" "Scer\VBA5, Scer\HXT2, Scer\HXT10" "Cele\hpo-12, Cele\spin-3, Cele\F47B8.10, Cele\spin-2, Cele\spin-4, Cele\spin-1" "Xtro\spns2, Xtro\spns1" "Mmus\Spns1, Mmus\Spns3, Mmus\Spns2" "Hsap\SPNS1, Hsap\SPNS3, Hsap\SPNS2" FBgn0028979 tio tiptop http://flybase.org/reports/FBgn0028979 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000281113 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from biological aspect of ancestor with PANTHER:PTN000281113" "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype epidermis morphogenesis ; GO:0048730 | inferred from mutant phenotype specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype Malpighian tubule stellate cell differentiation ; GO:0061330 | inferred from expression pattern Malpighian tubule stellate cell differentiation ; GO:0061330 | inferred from genetic interaction with tsh" nucleus ; GO:0005634 | inferred from direct assay "CG12630, tio, Tio" "IPR013087:Zinc finger C2H2-type, IPR027008:Teashirt family, IPR026807:Protein tiptop/teashirt" CG12630 11-Aug-17 DroID_v2017_08 "Drer\tshz1, Drer\tshz3a" - - "Xtro\tshz3, Xtro\tshz2" "Mmus\Tshz1, Mmus\Tshz3, Mmus\Tshz2" "Hsap\TSHZ2, Hsap\TSHZ1, Hsap\TSHZ3" "viable,fertile,visible,homeotic" "antennal disc,eye,ectopic,somatic clone,larval labial segment,T1 beard,denticle,heat sensitive,eye photoreceptor cell,ectopic | third instar larval stage" FBgn0040308 Jafrac2 Thioredoxin peroxidase 2 http://flybase.org/reports/FBgn0040308 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Diap1 thioredoxin peroxidase activity ; GO:0008379 | inferred from direct assay "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway ; GO:2001269 | inferred from mutant phenotype apoptotic signaling pathway ; GO:0097190 | inferred from mutant phenotype inferred from genetic interaction with Diap1 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype cellular response to cold ; GO:0070417 | inferred from direct assay positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from genetic interaction with hop inferred from genetic interaction with Stat92E inferred from genetic interaction with dome hydrogen peroxide catabolic process ; GO:0042744 | inferred from direct assay defense response to bacterium ; GO:0042742 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG1274, DPx4156, Prx4156, Jafrac2, Jafrac-2, jafrac2, thioredoxin peroxidase 2 isoform A, DPx-4156, 1274, JafRac2, dPrx4, Prx4, Jafrac" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR013766:Thioredoxin domain" CG1274 11-Aug-17 DroID_v2017_08 "Drer\prdx1, Drer\prdx4, Drer\prdx6, Drer\prdx2, Drer\prdx3" "Scer\TSA1, Scer\PRX1, Scer\TSA2" "Cele\prdx-3, Cele\prdx-2, Cele\prdx-6" "Xtro\prdx3, Xtro\prdx4, Xtro\prdx2, Xtro\prdx1" "Mmus\Prdx2, Mmus\Prdx1, Mmus\Prdx3, Mmus\Prdx4, Mmus\Prdx6" "Hsap\PRDX1, Hsap\PRDX3, Hsap\PRDX2, Hsap\PRDX4, Hsap\PRDX6" "short lived,lethal,heat sensitive,increased cell death,viable,fertile,oxidative stress response defective,recessive,chemical sensitive" eye FBgn0033476 oys oysgedart http://flybase.org/reports/FBgn0033476 protein_coding_gene lysophospholipid acyltransferase activity ; GO:0071617 | inferred from direct assay lipid modification ; GO:0030258 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from genetic interaction with nes plasma membrane organization ; GO:0007009 | inferred from genetic interaction with nes sperm individualization ; GO:0007291 | inferred from genetic interaction with nes membrane ; GO:0016020 | inferred from direct assay "Oys, oys, CG18445" "IPR004299:Membrane bound O-acyl transferase, MBOAT" CG18445 11-Aug-17 DroID_v2017_08 "Drer\mboat2a, Drer\mboat2b, Drer\mboat1, Drer\mboat4" Scer\ALE1 "Cele\mboa-3, Cele\mboa-4" "Xtro\mboat1, Xtro\mboat2" "Mmus\Mboat2, Mmus\Mboat4, Mmus\Mboat1" "Hsap\MBOAT4, Hsap\MBOAT1, Hsap\MBOAT2" "viable,fertile,neuroanatomy defective" "intersegmental nerve,anterior fascicle & synapse | supernumerary,synapse" DRSC05203 IE -0.827486377 -1.818943882 -2.509067786 -0.947443599 0.386414695 -0.03786959 FBgn0025381 rush rush hour http://flybase.org/reports/FBgn0025381 - protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 phosphatidylinositol binding ; GO:0035091 | inferred from direct assay endocytosis ; GO:0006897 | inferred from genetic interaction with car inferred from genetic interaction with Rab5 inferred from genetic interaction with VhaSFD inferred from genetic interaction with Hrs neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype endosome organization ; GO:0007032 | inferred from mutant phenotype early endosome ; GO:0005769 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay "CG14782, EG:80H7.5, rush" "IPR000306:FYVE zinc finger, IPR001849:Pleckstrin homology domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR011993:PH domain-like, IPR017455:Zinc finger, FYVE-related, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG14782 11-Aug-17 DroID_v2017_08 "Drer\plekhf2, Drer\plekhf1, Drer\plekhm2, Drer\zfyve16, Drer\zfyve9a, Drer\fyco1a, Drer\snx29" "Scer\PIB2, Scer\PIB1" "Cele\rabs-5, Cele\ZK632.12, Cele\aka-1" "Xtro\plekhf1, Xtro\plekhf2" "Mmus\Rufy4, Mmus\Zfyve16, Mmus\Zfyve9, Mmus\Plekhf2, Mmus\Fyco1, Mmus\Plekhm2, Mmus\Rufy1, Mmus\Plekhf1, Mmus\Snx29" "Hsap\PLEKHF1, Hsap\FYCO1, Hsap\FGD5, Hsap\PLEKHF2, Hsap\ZFYVE16, Hsap\RUFY1, Hsap\PLEKHM2, Hsap\SNX29, Hsap\ZFYVE9" "sleep defective,viable,fertile" late endosome FBgn0262954 Rpb12 Rpb12 http://flybase.org/reports/FBgn0262954 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006591 DNA-directed RNA polymerase activity ; GO:0003899 | non-traceable author statement RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000248542 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000248542 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000248542 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with UniProtKB:P53803 transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from biological aspect of ancestor with PANTHER:PTN000248542 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000248542 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN000248542 DNA-directed RNA polymerase II, core complex ; GO:0005665 | non-traceable author statement DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with UniProtKB:P53803" "CG34186, RPB12, Rpb12" "IPR006591:RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4, IPR029040:RNA polymerase subunit RPABC4/transcription elongation factor Spt4" CG34186 11-Aug-17 DroID_v2017_08 Drer\polr2k Scer\RPC10 Cele\rpb-12 Xtro\polr2k Mmus\Polr2k Hsap\POLR2K FBgn0032821 CdGAPr Cd GTPase activating protein-related http://flybase.org/reports/FBgn0032821 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN001813090 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with MGI:MGI:2673998 retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype small GTPase mediated signal transduction ; GO:0007264 | inferred from biological aspect of ancestor with PANTHER:PTN001813090 cellular_component ; GO:0005575 | no biological data available "CG10538, 10538, d-CdGAPr, GAP, CdGAPr, cdGAPr, FBgn 32821" "IPR000198:Rho GTPase-activating protein domain, IPR001452:SH3 domain, IPR008936:Rho GTPase activation protein" CG10538 11-Aug-17 DroID_v2017_08 "Drer\arhgap27l, Drer\arhgap12a, Drer\arhgap23a, Drer\arhgap31, Drer\arhgap33, Drer\arhgap32a, Drer\arhgap24, Drer\bcr, Drer\arhgap9, Drer\si:ch73-203a8.1, Drer\arhgap32b, Drer\si:dkey-191m6.4, Drer\si:ch211-247j9.1, Drer\arhgap22, Drer\arhgap21b" "Scer\BEM2, Scer\RGD1, Scer\RGA1" "Cele\tag-325, Cele\rrc-1, Cele\pac-1" "Xtro\arhgap25, Xtro\arhgap24, Xtro\bcr, Xtro\arhgap30, Xtro\arhgap21, Xtro\arhgap33, Xtro\arhgap32, Xtro\arhgap22" "Mmus\Arhgap24, Mmus\Arhgap22, Mmus\Arhgap32, Mmus\Arhgap25, Mmus\Arhgap33, Mmus\Arhgap21, Mmus\Arhgap30, Mmus\Arhgap27, Mmus\Arhgap31, Mmus\Arhgap15, Mmus\Arhgap23, Mmus\Arhgap9, Mmus\Bcr" "Hsap\ARHGAP15, Hsap\ARHGAP33, Hsap\ARHGAP23, Hsap\ARHGAP25, Hsap\ARHGAP30, Hsap\ARHGAP32, Hsap\ARHGAP22, Hsap\ARHGAP9, Hsap\ARHGAP27, Hsap\ARHGAP24, Hsap\BCR, Hsap\ARHGAP31, Hsap\ARHGAP21" "viable,fertile,neuroanatomy defective" embryonic/larval optic stalk DRSC03289 K 0.323874705 1.013299345 0.305306149 0.965144837 2.472255767 0.660543908 FBgn0041171 ago archipelago http://flybase.org/reports/FBgn0041171 protein_coding_gene cyclin binding ; GO:0030332 | traceable author statement ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000001885 protein binding ; GO:0005515 | inferred from physical interaction with mi "negative regulation of cellular response to hypoxia ; GO:1900038 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype regulation of exit from mitosis ; GO:0007096 | traceable author statement cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype regulation of mitophagy ; GO:1903146 | inferred from mutant phenotype trachea development ; GO:0060438 | inferred from mutant phenotype inferred from genetic interaction with Vhl SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence or structural similarity with HGNC:16712 negative regulation of glial cell proliferation ; GO:0060253 | inferred from genetic interaction with slmb regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | traceable author statement" SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with HGNC:16712 SCF ubiquitin ligase complex ; GO:0019005 | non-traceable author statement "cdc4, SCF[Ago], CG15010, DmFbw7, anon-WO0118547.345, ago, Ago, FBXW3, FBXW7" "IPR001680:WD40 repeat, IPR001810:F-box domain, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like" CG15010 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-154o6.3, Drer\fbxw11b, Drer\fbxw7, Drer\ect2l, Drer\traf7, Drer\fbxw11a, Drer\daw1" "Scer\MET30, Scer\UFO1, Scer\CDC4, Scer\RRT13" "Cele\lin-23, Cele\scp-1, Cele\sel-10" "Xtro\btrc, Xtro\fbxw7, Xtro\traf7, Xtro\LOC100488030, Xtro\daw1" "Mmus\Fbxo16, Mmus\Fbxw7, Mmus\Traf7, Mmus\Fbxw11, Mmus\Btrc, Mmus\Daw1" "Hsap\DAW1, Hsap\BTRC, Hsap\TRAF7, Hsap\FBXW11, Hsap\FBXW7" "neuroanatomy defective,somatic clone,lethal,some die during second instar larval stage,some die during third instar larval stage,oxidative stress response defective,visible,increased cell size,recessive,increased cell number,lethal - all die before end of first instar larval stage,some die during first instar larval stage,mitotic cell cycle defective,small body,decreased cell size" "lateral H branch,lateral G branch,tracheole,supernumerary,embryonic/larval ganglionic branch,wing,posterior,wing vein,nurse cell,germline clone,nurse cell & nucleus | germ-line clone,wing disc,somatic clone,eye,RP2 motor neuron,ectopic,embryonic/larval tracheal system,embryonic/larval dorsal trunk,tracheal lumen,embryonic/larval lateral trunk,embryonic/larval dorsal branch,tracheal primordium,tracheal fusion cell,secondary pigment cell,tertiary pigment cell,interommatidial bristle,mitotic cell cycle | somatic clone,embryonic/larval trachea,conditional,follicle cell & nucleus | somatic clone,posterior compartment,heat sensitive,lateral F branch,cell non-autonomous" DRSC08463 I 0.713483512 4.150537993 1.466765347 1.472022389 0.126602644 -0.528701757 FBgn0010391 Gtp-bp GTP-binding protein http://flybase.org/reports/FBgn0010391 "FBgn0025711, FBgn0030267" protein_coding_gene "signal recognition particle binding ; GO:0005047 | inferred from electronic annotation with InterPro:IPR007222 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000897, InterPro:IPR007222, InterPro:IPR013822 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR007222 RNA binding ; GO:0003723 | non-traceable author statement" "SRP-dependent cotranslational protein targeting to membrane ; GO:0006614 | inferred from electronic annotation with InterPro:IPR000897, InterPro:IPR013822 axonogenesis ; GO:0007409 | inferred from expression pattern regulation of protein secretion ; GO:0050708 | inferred from expression pattern" signal recognition particle receptor complex ; GO:0005785 | inferred from electronic annotation with InterPro:IPR007222 lipid particle ; GO:0005811 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay "SrpRalpha, CG2522, CK00309, BEST:CK00309, Gtp-bp, GTP-bp, mAb 13D5" "IPR000897:Signal recognition particle, SRP54 subunit, GTPase domain, IPR003593:AAA+ ATPase domain, IPR013822:Signal recognition particle, SRP54 subunit, helical bundle, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR007222:Signal recognition particle receptor, alpha subunit, N-terminal, IPR011012:Longin-like domain" CG2522 11-Aug-17 DroID_v2017_08 Drer\srpr Scer\SRP101 Cele\F38A1.8 Xtro\srpra Mmus\Srpr Hsap\SRPRA lethal DRSC20251 I -0.848398353 1.641460526 0.21777279 0.413860062 0.66287942 0.506695935 FBgn0262579 Ect4 Ectoderm-expressed 4 http://flybase.org/reports/FBgn0262579 protein_coding_gene - signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001123587 regulation of neuron death ; GO:1901214 | inferred from mutant phenotype response to axon injury ; GO:0048678 | inferred from mutant phenotype neuronal cell body ; GO:0043025 | inferred from direct assay neuron projection ; GO:0043005 | inferred from direct assay dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000543268 "CG43119, Ect4/SARM, dsarm, CG34373, CG7915, CG7905, anon-WO0118547.272, Ect4, CG13680, CG13681, ect4, dSarm, dSARM" "IPR011989:Armadillo-like helical, IPR001660:Sterile alpha motif domain, IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR016024:Armadillo-type fold, IPR013761:Sterile alpha motif/pointed domain" CG43119 11-Aug-17 DroID_v2017_08 Drer\sarm1 - Cele\tir-1 Xtro\sarm1 Mmus\Sarm1 "Hsap\SARM1, Hsap\TMEM199" embryonic stage | cellular blastoderm dorsal ectoderm anlage | restricted

DRSC10039 EK FBgn0001906 l(2)24Dd lethal (2) 24Dd http://flybase.org/reports/FBgn0001906 - gene - - - "jf2, l(2)jf2, l(2)24Dd" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0265217 fs(2)Z2-5646 - http://flybase.org/reports/FBgn0265217 gene - - - fs(2)Z2-5646 - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0262456 mir-125 mir-125 stem loop http://flybase.org/reports/FBgn0262456 miRNA_gene - cellular response to ecdysone ; GO:0071390 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype - "dme-mir-125, mir-125, miR-125, 125, CR43029, mir-125b, CR33314, MiR-125b, dme-miR-125" - CR43029 11-Aug-17 DroID_v2017_08 - - - - - - " prepupal stage--adult stage , prepupal stage--pupal stage | stage P5 " organism

FBgn0032420 CG6583 - http://flybase.org/reports/FBgn0032420 protein_coding_gene - - cytosol ; GO:0005829 | inferred from direct assay CG6583 - CG6583 11-Aug-17 DroID_v2017_08 - - "Cele\K11H12.7, Cele\F35C5.11" - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0040638 CG12979 - http://flybase.org/reports/FBgn0040638 protein_coding_gene - - - CG12979 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0083057 snoRNA:Psi18S-110 snoRNA:Psi18S-110 http://flybase.org/reports/FBgn0083057 snoRNA_gene - - - "snoRNA:Psi18S-110, psi18s-110, Psi 18S-110, CR34631, chr3L:815446..815549" - CR34631 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0026241 gar gargantua http://flybase.org/reports/FBgn0026241 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available gar - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0038886 CG6475 - http://flybase.org/reports/FBgn0038886 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG6475 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG6475 11-Aug-17 DroID_v2017_08 "Drer\ugt2a5, Drer\ugt5b3, Drer\ugt5c2, Drer\ugt2b6, Drer\ugt5d1, Drer\ugt8, Drer\ugt5b1, Drer\ugt5g2, Drer\ugt1b2, Drer\ugt5a4, Drer\ugt1b4, Drer\ugt5a5, Drer\ugt1ab, Drer\ugt5f1, Drer\ugt2b1, Drer\ugt5b6, Drer\ugt5b2, Drer\ugt1b3, Drer\ugt5a2, Drer\ugt2b3, Drer\ugt2a6, Drer\ugt5c1, Drer\ugt2b5, Drer\ugt5a1, Drer\ugt1b5, Drer\ugt5b4, Drer\zgc:172315, Drer\ugt5e1, Drer\ugt5g1, Drer\ugt5c3, Drer\ugt1b7, Drer\ugt2a2" Scer\ATG26 "Cele\ugt-47, Cele\ugt-59, Cele\ugt-53, Cele\ugt-12, Cele\ugt-21, Cele\ugt-45, Cele\ugt-15, Cele\ugt-38, Cele\ugt-10, Cele\ugt-22, Cele\ugt-34, Cele\ugt-56, Cele\ugt-57, Cele\ugt-49, Cele\Y43D4A.2, Cele\ugt-51, Cele\ugt-42, Cele\ugt-50, Cele\ugt-55, Cele\ugt-24, Cele\ugt-62, Cele\ugt-32, Cele\ugt-37, Cele\ugt-36, Cele\ugt-13, Cele\ugt-23, Cele\F10D2.8, Cele\ugt-18, Cele\ugt-43, Cele\ugt-46, Cele\C55H1.1, Cele\ugt-7, Cele\ugt-19, Cele\ugt-25, Cele\ugt-60, Cele\ugt-52, Cele\ugt-8, Cele\ugt-26, Cele\ugt-58, Cele\ugt-65, Cele\K04A8.10, Cele\ugt-28, Cele\ugt-48, Cele\ugt-35, Cele\ugt-17, Cele\ugt-11, Cele\ugt-33, Cele\ugt-9, Cele\ugt-5, Cele\ugt-3, Cele\ugt-27, Cele\ugt-1, Cele\ugt-30, Cele\ugt-29, Cele\H23N18.4, Cele\ugt-6, Cele\F54C1.1, Cele\ugt-31, Cele\ugt-14, Cele\ugt-2, Cele\ugt-16, Cele\ugt-54, Cele\ugt-44, Cele\ugt-40, Cele\ugt-39, Cele\ugt-61, Cele\C23G10.6, Cele\C03A7.13, Cele\ugt-20, Cele\C03A7.12, Cele\ugt-4, Cele\ugt-41" "Xtro\ugt2b4, Xtro\ugt8, Xtro\ugt1a6, Xtro\ugt3a2, Xtro\ugt2a1" "Mmus\Ugt2b35, Mmus\Ugt2b38, Mmus\Ugt3a1, Mmus\Ugt2a3, Mmus\Ugt2b36, Mmus\Ugt1a6b, Mmus\Ugt3a2, Mmus\Ugt1a7c, Mmus\Ugt8a, Mmus\Ugt2b37, Mmus\Ugt2a1, Mmus\Ugt1a9, Mmus\Ugt2b5, Mmus\Ugt1a5, Mmus\Ugt1a6a, Mmus\Ugt2b1, Mmus\Ugt2b34, Mmus\Ugt1a1, Mmus\Ugt1a10, Mmus\Ugt1a2, Mmus\Ugt2a2" "Hsap\UGT2B15, Hsap\UGT1A3, Hsap\UGT3A1, Hsap\UGT1A9, Hsap\UGT1A5, Hsap\UGT3A2, Hsap\UGT8, Hsap\UGT2B10, Hsap\UGT1A1, Hsap\UGT1A7, Hsap\UGT2B17, Hsap\UGT2B11, Hsap\UGT1A6, Hsap\UGT1A4, Hsap\UGT2A3, Hsap\UGT1A8, Hsap\UGT2A2, Hsap\UGT1A10, Hsap\UGT2B4, Hsap\UGT2B28, Hsap\UGT2B7" "viable,fertile,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0264089 sli slit http://flybase.org/reports/FBgn0264089 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 protein binding ; GO:0005515 | inferred from physical interaction with robo1 heparin binding ; GO:0008201 | inferred from direct assay Roundabout binding ; GO:0048495 | inferred from physical interaction with robo1" "embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with Sos mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype mesodermal cell migration ; GO:0008078 | inferred from mutant phenotype induction of negative chemotaxis ; GO:0050929 | inferred from mutant phenotype Roundabout signaling pathway ; GO:0035385 | inferred from genetic interaction with robo1 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype salivary gland boundary specification ; GO:0007432 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with robo1 inferred from physical interaction with robo1 neuron migration ; GO:0001764 | inferred from mutant phenotype regulation of epithelial cell migration ; GO:0010632 | inferred from mutant phenotype outflow tract morphogenesis ; GO:0003151 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype digestive tract mesoderm development ; GO:0007502 | inferred from mutant phenotype neuron differentiation ; GO:0030182 | inferred from mutant phenotype regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype" Slit-Robo signaling complex ; GO:0071666 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | traceable author statement "sli, Slit, slit, CG33464, CG43758, fus3, CT37068, CT21700, dSlit, l(2)05248, wdh, CG8355, Sli" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR009030:Growth factor receptor cysteine-rich domain, IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR000742:EGF-like domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001791:Laminin G domain, IPR006207:Cystine knot, C-terminal, IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR003591:Leucine-rich repeat, typical subtype, IPR000372:Leucine-rich repeat N-terminal domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site" CG43758 11-Aug-17 DroID_v2017_08 "Drer\lrrc17, Drer\rtn4rl2a, Drer\lrrc3ca, Drer\slit3, Drer\slit1a, Drer\lrrc3cb, Drer\dcn, Drer\nyx, Drer\lrrc3b, Drer\slit2, Drer\slit1b, Drer\lrrc3" - "Cele\lron-12, Cele\lron-1, Cele\sym-1, Cele\slt-1" "Xtro\lrrc3b, Xtro\slit1, Xtro\adgra3, Xtro\nyx, Xtro\slit2, Xtro\slit3, Xtro\rtn4r, Xtro\lrrc3" "Mmus\Lrrc3b, Mmus\Lrrc3, Mmus\Nyx, Mmus\Slit3, Mmus\Lrrc17, Mmus\Vasn, Mmus\Adgra3, Mmus\Slit1, Mmus\Slit2" "Hsap\SLIT2, Hsap\VASN, Hsap\ECM2, Hsap\LRRC3C, Hsap\LRRC3B, Hsap\NYX, Hsap\LRRC17, Hsap\ADGRA3, Hsap\SLIT3, Hsap\LRRC3, Hsap\SLIT1" " embryonic stage | extended germ band , embryonic stage | stage 17 , embryonic stage | stage 15 , embryonic stage | stage 10 , embryonic stage | stage 13 , embryonic stage | gastrula , embryonic stage | stage 6 " " mesectoderm &&of ventral midline

, neuropil

, cardioblast

, ectoderm | lateral

segmentally repeated , embryonic central nervous system | restricted

, ectoderm | presumptive

, midline glial cell

" " embryonic stage | gastrula , embryonic stage | extended germ band , embryonic stage | stage 15 , embryonic stage | stage 13 , embryonic stage | stage 13-16 , embryonic stage | stage 13-15 " " ventral midline &&of mesectoderm

, cardioblast

, midline glial cell

, neuron &&of embryonic central nervous system

, ventral midline

, epidermis | dorsal & lateral

, longitudinal connective | restricted

" FBgn0053860 His3:CG33860 His3:CG33860 http://flybase.org/reports/FBgn0053860 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33860, His3:CG33860" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33860 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.25, Drer\zgc:113984, Drer\h3f3c, Drer\LOC108190746, Drer\h3f3b.1, Drer\LOC108190747, Drer\h3f3a, Drer\si:ch73-36p18.2, Drer\zgc:113983, Drer\hist2h3c, Drer\cenpa, Drer\si:ch1073-429i10.3, Drer\zgc:173552, Drer\h3f3d, Drer\hist2h3ca1" "Scer\HHT1, Scer\CSE4, Scer\HHT2" "Cele\his-6, Cele\his-13, Cele\his-49, Cele\his-42, Cele\his-72, Cele\his-74, Cele\his-63, Cele\his-25, Cele\his-9, Cele\his-2, Cele\his-17, Cele\his-55, Cele\his-32, Cele\his-71, Cele\his-45, Cele\his-59, Cele\his-69, Cele\his-27" "Xtro\hist2h3d, Xtro\cenpa, Xtro\h3f3b, Xtro\LOC100493041" "Mmus\Hist2h3c2, Mmus\Hist1h3g, Mmus\Hist1h3f, Mmus\Hist1h3a, Mmus\Hist1h3b, Mmus\Hist1h3i, Mmus\Hist1h3e, Mmus\Hist1h3h, Mmus\H3f3a, Mmus\Hist2h3c1, Mmus\Cenpa, Mmus\Hist1h3c, Mmus\Hist1h3d, Mmus\H3f3b, Mmus\Hist2h3b" "Hsap\HIST2H3A, Hsap\HIST1H3A, Hsap\HIST1H3I, Hsap\HIST1H3F, Hsap\HIST1H3G, Hsap\HIST1H3D, Hsap\HIST2H3C, Hsap\H3F3B, Hsap\HIST1H3H, Hsap\HIST2H3D, Hsap\H3F3A, Hsap\HIST1H3B, Hsap\HIST3H3, Hsap\CENPA, Hsap\HIST1H3J, Hsap\HIST1H3E, Hsap\HIST1H3C, Hsap\H3F3C" FBgn0053847 His2A:CG33847 His2A:CG33847 http://flybase.org/reports/FBgn0053847 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33847, His2A:CG33847" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33847 11-Aug-17 DroID_v2017_08 "Drer\LOC100332229, Drer\si:ch1073-159d7.10, Drer\si:ch73-368j24.14, Drer\si:dkey-261m9.11, Drer\zgc:173652, Drer\zgc:101846, Drer\LOC570115, Drer\si:ch73-36p18.5, Drer\LOC100334934, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.20, Drer\zgc:114037, Drer\si:ch211-113a14.19, Drer\LOC100148591, Drer\si:dkey-23a13.14, Drer\si:ch211-113a14.26, Drer\si:dkey-23a13.7, Drer\si:dkey-261m9.18, Drer\si:ch73-368j24.13, Drer\si:dkey-261m9.7, Drer\zgc:195633, Drer\zgc:154164, Drer\zgc:110434, Drer\si:dkey-108k21.15, Drer\si:dkey-108k21.26, Drer\si:dkey-108k21.19, Drer\si:ch211-113a14.16, Drer\si:dkey-261m9.15, Drer\fbxl6, Drer\h2afy2, Drer\si:ch1073-159d7.11, Drer\h2afx, Drer\si:ch211-113a14.7" "Scer\HTA2, Scer\HTA1" "Cele\his-16, Cele\his-30, Cele\his-21, Cele\his-61, Cele\his-68, Cele\his-7, Cele\his-3, Cele\htas-1, Cele\his-51, Cele\his-65, Cele\his-53, Cele\his-43, Cele\his-12, Cele\his-47, Cele\his-35, Cele\his-19, Cele\his-57, Cele\his-33" "Xtro\h2afx, Xtro\hist1h2ah, Xtro\hist1h2ad, Xtro\hist1h2aj, Xtro\h2afy2, Xtro\h2afj, Xtro\hist1h2am, Xtro\hist1h2aa, Xtro\h2afy" "Mmus\Hist1h2ag, Mmus\Hist1h2af, Mmus\H2al2b, Mmus\Hist2h2aa1, Mmus\Hist1h2ae, Mmus\Hist1h2ah, Mmus\Hist2h3c1, Mmus\H2afb2, Mmus\Gm14920, Mmus\Hist1h2ac, Mmus\Hist1h2an, Mmus\H2afj, Mmus\Hist3h2a, Mmus\Hist2h2ab, Mmus\H2afy, Mmus\H2al1n, Mmus\Hist1h2ai, Mmus\H2al2c, Mmus\Hist1h2ao, Mmus\Hist1h2ab, Mmus\Hist2h2ac, Mmus\H2afb3, Mmus\H2afy2, Mmus\Hist1h2ad, Mmus\Hist2h2aa2, Mmus\H2afx, Mmus\H2afb1, Mmus\Hist1h2ap, Mmus\Hist1h2ak, Mmus\H2al1j, Mmus\Hist1h2aa" "Hsap\HIST1H2AH, Hsap\HIST1H2AD, Hsap\HIST1H2AB, Hsap\HIST1H2AM, Hsap\HIST1H2AC, Hsap\HIST2H2AA3, Hsap\HIST1H2AK, Hsap\HIST1H2AA, Hsap\H2AFB1, Hsap\H2AFJ, Hsap\HIST1H2AI, Hsap\HIST2H2AC, Hsap\HIST2H2AA4, Hsap\HIST2H2AB, Hsap\HIST3H2A, Hsap\H2AFB3, Hsap\HIST1H2AE, Hsap\HIST1H2AG, Hsap\H2AFB2, Hsap\HIST1H2AJ, Hsap\H2AFX, Hsap\HIST1H2AL, Hsap\H2AFY2, Hsap\H2AFY" FBgn0013981 His4r Histone H4 replacement http://flybase.org/reports/FBgn0013981 FBgn0064800 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR004823, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "His4R, H4r, His4-88CD, CG3379, BcDNA:RH52884, His4r, FBtr0082962" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG3379 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-36p18.4, Drer\si:ch73-368j24.1, Drer\si:ch211-113a14.17, Drer\hist1h4l, Drer\si:dkey-108k21.28, Drer\si:dkey-261m9.18, Drer\si:dkey-108k21.19, Drer\LOC794549, Drer\si:dkey-23a13.7, Drer\zgc:154164, Drer\si:ch73-368j24.14, Drer\si:ch211-113a14.6, Drer\LOC100329358, Drer\zgc:194989, Drer\si:dkey-108k21.12, Drer\si:dkey-261m9.17, Drer\zgc:153409, Drer\LOC100150038, Drer\LOC570405, Drer\LOC100331412, Drer\si:ch73-36p18.3, Drer\si:ch211-113a14.26, Drer\zgc:163040, Drer\LOC562770" "Scer\HHF1, Scer\HHF2" "Cele\his-37, Cele\his-14, Cele\his-60, Cele\his-56, Cele\his-26, Cele\his-28, Cele\his-31, Cele\his-5, Cele\his-67, Cele\his-1, Cele\his-10, Cele\his-50, Cele\his-18, Cele\his-64, Cele\his-38, Cele\his-46" "Xtro\LOC100485271, Xtro\hist1h4c, Xtro\LOC100493041, Xtro\hist1h4k, Xtro\hist1h4a" "Mmus\Hist4h4, Mmus\Hist1h4c, Mmus\Hist1h4d, Mmus\Hist2h4, Mmus\Hist1h4h, Mmus\Hist1h4f, Mmus\Hist1h4b, Mmus\Hist1h4k, Mmus\Hist1h4i, Mmus\Hist1h4n, Mmus\Hist1h4m, Mmus\Hist1h4j, Mmus\Hist1h4a" "Hsap\HIST1H4B, Hsap\HIST1H4A, Hsap\HIST4H4, Hsap\HIST1H4D, Hsap\HIST1H4F, Hsap\HIST1H4L, Hsap\HIST1H4C, Hsap\HIST2H4B, Hsap\HIST1H4G, Hsap\HIST1H4H, Hsap\HIST1H4I, Hsap\HIST2H4A, Hsap\HIST1H4J, Hsap\HIST1H4K, Hsap\HIST1H4E" DRSC16703 IEK -3.755480914 -2.396585983 -3.980870015 -7.573715726 -4.210531337 -2.537249305 FBgn0266354 CG45002 - http://flybase.org/reports/FBgn0266354 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR001375 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001375, InterPro:IPR002469" - "CG45002, CG34326, CG9059, BcDNA:GH06235" "IPR029058:Alpha/Beta hydrolase fold, IPR002469:Dipeptidylpeptidase IV, N-terminal domain, IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain" CG45002 11-Aug-17 DroID_v2017_08 "Drer\dpp4, Drer\dpp6b, Drer\LOC101886435, Drer\LOC101883320, Drer\zgc:136971, Drer\dpp6a, Drer\fap, Drer\apeh" "Scer\DAP2, Scer\STE13" "Cele\dpf-2, Cele\dpf-1" "Xtro\apeh, Xtro\dpp4, Xtro\dpp10, Xtro\dpp6" "Mmus\Apeh, Mmus\Dpp6, Mmus\Dpp4, Mmus\Fap, Mmus\Dpp10" "Hsap\APEH, Hsap\FAP, Hsap\DPP6, Hsap\DPP4, Hsap\DPP10" FBgn0030795 ppk28 pickpocket 28 http://flybase.org/reports/FBgn0030795 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 "drinking behavior ; GO:0042756 | inferred from mutant phenotype response to water ; GO:0009415 | inferred from direct assay liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 cellular response to water stimulus ; GO:0071462 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK28, CG4805, ppk28" IPR001873:Epithelial sodium channel CG4805 11-Aug-17 DroID_v2017_08 "Drer\asic4b, Drer\asic1c, Drer\asic1a, Drer\asic4a, Drer\asic1b, Drer\asic2" - "Cele\delm-1, Cele\del-7, Cele\acd-2, Cele\asic-2, Cele\del-8, Cele\del-6, Cele\delm-2, Cele\acd-3, Cele\mec-10, Cele\acd-1, Cele\unc-105, Cele\del-1, Cele\del-4, Cele\flr-1" "Xtro\asic1, Xtro\scnn1b, Xtro\asic5, Xtro\scnn1d, Xtro\scnn1g, Xtro\scnn1a, Xtro\asic4" "Mmus\Asic5, Mmus\Scnn1g, Mmus\Scnn1b, Mmus\Asic4, Mmus\Asic3, Mmus\Asic1, Mmus\Scnn1a, Mmus\Asic2" "Hsap\SCNN1B, Hsap\ASIC2, Hsap\SCNN1A, Hsap\ASIC3, Hsap\ASIC1, Hsap\SCNN1D, Hsap\SCNN1G, Hsap\ASIC4, Hsap\ASIC5" "neurophysiology defective,taste perception defective,proboscis extension reflex defective,viable" labellar taste bristle FBgn0002985 odd odd skipped http://flybase.org/reports/FBgn0002985 FBgn0010502 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity DNA binding ; GO:0003677 | non-traceable author statement" "Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay pattern specification process ; GO:0007389 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay periodic partitioning by pair rule gene ; GO:0007366 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay" nucleus ; GO:0005634 | inferred from sequence or structural similarity "odd, ODD, CG3851, Odd, l(2)01863, ods" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3851 11-Aug-17 DroID_v2017_08 "Drer\osr1, Drer\egr2b, Drer\klf11a, Drer\klf15, Drer\egr1, Drer\sp2, Drer\si:ch211-117k10.3, Drer\osr2, Drer\egr4" "Scer\CRZ1, Scer\CMR3, Scer\MSN4, Scer\YPR015C, Scer\FZF1, Scer\MSN2" "Cele\odd-2, Cele\egrh-1, Cele\egrh-3, Cele\odd-1" "Xtro\osr1, Xtro\osr2, Xtro\egr3, Xtro\sp2, Xtro\klf15, Xtro\klf11, Xtro\egr1, Xtro\egr2" "Mmus\Egr4, Mmus\Osr2, Mmus\Sp2, Mmus\Egr1, Mmus\Klf11, Mmus\Klf15, Mmus\Egr3, Mmus\Osr1" "Hsap\EGR3, Hsap\EGR4, Hsap\SP2, Hsap\KLF11, Hsap\OSR2, Hsap\KLF15, Hsap\EGR1, Hsap\OSR1, Hsap\EGR2" " embryonic stage | stage 6-9 , embryonic stage | stage 4 , embryonic stage | stage >=6 , embryonic stage | late , embryonic stage | stage 5 , pupal stage , larval stage | third instar " "

segment polarity , organism | 60% egg length

, garland cell

, organism | pair rule

, Malpighian tubule

, leg | restricted

, ventral nerve cord

, embryonic/larval proventriculus

, organism | 90-100% egg length

, pericardial cell

, embryonic brain

, ventral thoracic disc | restricted

, pharyngeal muscle

" "visible,partially lethal - majority die,lethal,recessive,pair rule phenotype,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,segment polarity phenotype,somatic clone" "adult thorax,pupal thorax,embryonic abdominal segment 1,anterior,embryonic abdominal segment 3,embryonic abdominal segment 5,embryonic abdominal segment 7,embryonic segment,mouth hooks,dental sclerite,denticle belt,embryonic/first instar larval cuticle,embryonic head,abdominal 1 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 9 ventral denticle belt,mesothoracic ventral denticle belt,embryonic labial segment,embryonic maxillary segment,tarsal segment 2,somatic clone,tarsal segment 3,tarsal segment 4,metatarsus,tarsal segment,segment,apodeme,pretarsus,mesothoracic segment & embryonic epidermis,abdominal segment 1 & embryonic epidermis,abdominal segment 3 & embryonic epidermis,abdominal segment 5 & embryonic epidermis,abdominal segment 7 & embryonic epidermis,leg & adult cuticleptc-559.1,ventral thoracic disc,leg & adult cuticle | somatic clone" FBgn0037345 rev7 rev7 http://flybase.org/reports/FBgn0037345 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay positive regulation of lyase activity ; GO:0051349 | inferred from direct assay - "DmREV7, CG2948, rev7, Rev7, mad2B" IPR003511:HORMA domain CG2948 11-Aug-17 DroID_v2017_08 Drer\si:dkey-23c22.2 "Scer\MAD2, Scer\REV7" - Xtro\mad2l2 Mmus\Mad2l2 Hsap\MAD2L2 "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0262740 Evi5 Ecotropic viral integration site 5 http://flybase.org/reports/FBgn0262740 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab6 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab11 GTPase activator activity ; GO:0005096 | inferred from direct assay inferred from physical interaction with Rab11 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 regulation of cell migration ; GO:0030334 | inferred from direct assay border follicle cell migration ; GO:0007298 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of protein localization ; GO:0032880 | inferred from direct assay regulation of GTPase activity ; GO:0043087 | inferred from direct assay intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 cytoplasm ; GO:0005737 | inferred from direct assay recycling endosome ; GO:0055037 | colocalizes_with inferred from direct assay vesicle ; GO:0031982 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG11727, BcDNA:GH08923, BcDNA:LD11130, MRE21, Evi5" "IPR031214:Ecotropic viral integration site 5 protein, IPR000195:Rab-GTPase-TBC domain" CG11727 11-Aug-17 DroID_v2017_08 "Drer\tbc1d4, Drer\evi5a, Drer\tbc1d1, Drer\evi5b, Drer\si:ch211-266k8.4, Drer\si:ch211-239f4.1" "Scer\GYL1, Scer\GYP5" "Cele\myo-1, Cele\tbc-1, Cele\eat-17" "Xtro\tbc1d1, Xtro\tbc1d4, Xtro\evi5l, Xtro\evi5" "Mmus\Tbc1d4, Mmus\Evi5, Mmus\Tbc1d1, Mmus\Evi5l" "Hsap\EVI5, Hsap\TBC1D1, Hsap\TBC1D4, Hsap\EVI5L" FBgn0028734 Fmr1 Fmr1 http://flybase.org/reports/FBgn0028734 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W596 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VF87 protein binding ; GO:0005515 | inferred from physical interaction with piwi inferred from physical interaction with vas protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VD44 RNA binding ; GO:0003723 | inferred from physical interaction with Dscam1 RNA binding ; GO:0003723 | inferred from direct assay translation regulator activity ; GO:0045182 | inferred from mutant phenotype protein self-association ; GO:0043621 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Rm62 inferred from physical interaction with RpL11 inferred from physical interaction with Dcr-1 inferred from physical interaction with RpL5 inferred from physical interaction with AGO2 "axon guidance=0007411 |...inferred from genetic interaction with Sra-1 <> negative regulation of synapse assembly=0051964 |...<> regulation of cell proliferation=0042127 |...inferred from genetic interaction with Cbl <> axon guidance=0007411 |...<> locomotion=0040011 | traceable author statement <> positive regulation of programmed cell death=0043068 |...<> short-term memory=0007614 | NOT inferred from<> locomotor rhythm=0045475 |...<> mitotic cell cycle, embryonic=0045448 |...<> axonal fasciculation=0007413 |...<> negative regulation of insulin receptor signaling pathway=0046627 |...<> circadian rhythm=0007623 |...<> chemical synaptic transmission=0007268 | NOT inferred from<> germarium-derived oocyte fate determination=0007294 |...<> heterochromatin assembly=0031507 |...<> long-term memory=0007616 |...<> negative regulation of dendrite morphogenesis=0050774 |...<> cellularization=0007349 |... direct assay <> synapse assembly=0007416 | <> larval locomotory behavior=0008345 |...<> circadian sleep/wake cycle, sleep=0050802 |...<> regulation of translation=0006417 |...<> regulation of neuromuscular synaptic transmission=1900073 |...<> regulation of mitotic cell cycle, embryonic=0009794 |... genetic interaction with Capr <> circadian rhythm=0007623 | traceable author statement <> axonogenesis=0007409 |...<> synapse organization=0050808 |...<> social behavior=0035176 |...<> pole cell formation=0007279 |...<> detection of mechanical stimulus involved in sensory perception of touch=0050976 |...<> regulation of translation=0006417 | <> negative regulation of translation=0017148 |... expression pattern inferred from direct assay <> synaptic vesicle clustering=0097091 |...<> olfactory learning=0008355 |...<> oocyte dorsal/ventral axis specification=0007310 |... genetic interaction with orb <> regulation of synapse organization=0050807 |...inferred from genetic interaction with Sra-1 <> short-term memory=0007614 |...<> brain development=0007420 |...<> chemotaxis=0006935 | NOT inferred from<> male courtship behavior=0008049 | traceable author statement <> regulation of olfactory learning=0090328 |...<> mushroom body development=0016319 |...<> grooming behavior=0007625 |...<> negative regulation of synaptic growth at neuromuscular junction=0045886 |...<> germ-line cyst formation=0048134 |...inferred from genetic interaction with Cbl <> habituation=0046959 |...<> medium-term memory=0072375 |...<> adult locomotory behavior=0008344 |...<> neuron projection morphogenesis=0048812 |...<> regulation of synapse organization=0050807 |...<> dendrite morphogenesis=0048813 |...<> mRNA transport=0051028 |...<> male courtship behavior=0008049 |...<> negative regulation of imaginal disc growth=0045571 |... genetic interaction with rin inferred from genetic interaction with lig inferred from genetic interaction with Capr <> associative learning=0008306 |...<> cellularization=0007349 |... genetic interaction with Capr <> negative regulation of translation=0017148 |...<> positive regulation of neuroblast proliferation=0002052 |...<> negative regulation of translation=0017148 |... direct assay <> sperm axoneme assembly=0007288 |...<> regulation of synapse structural plasticity=0051823 |...<> germ cell development=0007281 |...<> germ cell development=0007281 |... genetic interaction with ban <> synaptic vesicle budding=0070142 |...<> regulation of dendrite morphogenesis=0048814 |...<> phototaxis=0042331 | NOT inferred from<> neuromuscular junction development=0007528 |... mutant phenotype" RISC complex ; GO:0016442 | traceable author statement lipid particle ; GO:0005811 | inferred from direct assay polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN001318100 neuronal ribonucleoprotein granule ; GO:0071598 | inferred from direct assay micro-ribonucleoprotein complex ; GO:0035068 | traceable author statement nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001318100 cytoplasm ; GO:0005737 | inferred from direct assay RISC complex ; GO:0016442 | inferred from physical interaction with AGO2 "dFMR1, dfmr1, CG6203, dFMR, FMRP, dfmr, dFMRP, FMR1, dFXR, Fmrp, dFmr1, FMRp, dfxr, dfxr1, fmr, FXR, dFXR1, dmfr1, EP(3)3517, AT24755, cg6203, fmr1, BcDNA:GM08679, Fmr1, dFmrp, FMR, dFXRP, DFMRP, DFmr1" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR015946:K homology domain-like, alpha/beta, IPR008395:Agenet-like domain, IPR022034:Fragile X-related 1 protein, C-terminal core" CG6203 11-Aug-17 DroID_v2017_08 "Drer\fxr2, Drer\fxr1, Drer\fmr1" - - "Xtro\fxr1, Xtro\fmr1" "Mmus\Fmr1, Mmus\Fxr2, Mmus\Fxr1" "Hsap\FXR2, Hsap\FMR1, Hsap\FXR1" " pupal stage&&adult stage , adult stage , pupal stage " " neuron

, adult brain

, brain

" "neurophysiology defective,endomitotic cell cycle defective,memory defective,neuroanatomy defective,learning defective,viable,flight defective,fertile,recessive,lethal - all die before end of P-stage,partially,some die during pharate adult stage,locomotor rhythm defective,lethal,visible,courtship behavior defective,dominant,semidominant,eclosion rhythm defective,partially lethal - majority live,wild-type,semi-sterile,sleep defective,somatic clone,male sterile,locomotor behavior defective,male,mitotic cell cycle defective,partially lethal - majority die,maternal effect,some die during embryonic stage,suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage,flightless,uncoordinated,some die during immature adult stage,increased cell death,temperature conditional,short lived,gravitaxis defective,conditional,heat stress response defective,heat sensitive,touch sensitivity defective,touch perception defective" "nurse cell,supernumerary,egg chamber,mushroom body beta-lobe,LNv neuron,rhabdomere R7,ventral adult lateral neuron & commissure[-],eye,ommatidium,synapse,neuromuscular junction & synapse,mushroom body alpha-lobe,embryonic/larval neuromuscular junction,NMJ bouton,adult mushroom body,dorsal cluster neuron & neurite[-],dorsal cluster neuron,neuron & beta-lobe,neuron & beta-lobe, with Fmr13,ventral adult lateral neuron & commissure,dorsal cluster neuron & neurite,retina,photoreceptor cell & synapse & lamina receptor cell,neuromuscular junction,testis,spermatid,spermatid axoneme,dorsal multidendritic neuron ddaC,mushroom body & neuron | somatic clone,mushroom body & neuron & dendrite | somatic clone,gamma-lobe & neuron | somatic clone,bouton,somatic clone,synaptic vesicle | somatic clone | supernumerary,s-LNv Pdf neuron,protocerebrum,axonemal microtubule,synapse, with Fmr1UAS.cZa, P2.4.Pdf,mechanosensory neuron,axon | ectopic,type I bouton,dendritic arborizing neuron,synapse & larval neuromuscular junction,germline cell,pole cell,pole bud,nucleus | embryonic cycle 13,condensed chromosome | embryonic stage,centrosome | embryonic stage,germline clone,maternal effect,germ cell & egg chamber,oocyte,ectopic,cycle 12 embryo,cycle 13 embryo,neuron & beta-lobe, with Fmr1I244N,neuron & beta-lobe, with Fmr1I307N,dorsal cluster neuron & neuriteato.3.6,rhabdomerehs.2sev,wing,photoreceptor cell,photoreceptor cell & synapse & lamina receptor cellhs.2sev,wing cell,anterior crossvein,wing margin,eye photoreceptor cell,pigment cell,mushroom body gamma-lobe,mushroom body & neuron | somatic cloneey-OK107,mushroom body & neuron & dendrite | somatic cloneey-OK107,gamma-lobe & neuron | somatic cloneey-OK107,neuromuscular junctionMhc.PW,synapseP2.4.Pdf,adult mushroom body beta'-lobe,synapse, with Fmr1‘î50M, P2.4.Pdf,adult brain,conditional" FBgn0038303 SIDL Shal Interactor of Di-Leucine Motif http://flybase.org/reports/FBgn0038303 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000004831 early endosome to Golgi transport ; GO:0034498 | inferred from biological aspect of ancestor with PANTHER:PTN000326892 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000004831 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with SGD:S000004831 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000326892 TRAPPII protein complex ; GO:1990071 | inferred from biological aspect of ancestor with PANTHER:PTN000326892 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000004831 "CG6623, SIDL" "IPR022233:TRAPP II complex, TRAPPC10, IPR011990:Tetratricopeptide-like helical domain" CG6623 11-Aug-17 DroID_v2017_08 Drer\trappc10 Scer\TRS130 Cele\trpp-10 Xtro\trappc10 Mmus\Trappc10 "Hsap\LOC102724200, Hsap\TRAPPC10" FBgn0053827 His3:CG33827 His3:CG33827 http://flybase.org/reports/FBgn0053827 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33827, His3:CG33827" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33827 11-Aug-17 DroID_v2017_08 "Drer\h3f3a, Drer\h3f3d, Drer\cenpa, Drer\zgc:113983, Drer\LOC108190747, Drer\hist2h3c, Drer\h3f3b.1, Drer\si:ch1073-429i10.3, Drer\si:ch73-36p18.2, Drer\zgc:113984, Drer\hist2h3ca1, Drer\zgc:173552, Drer\LOC108190746, Drer\h3f3c" "Scer\HHT1, Scer\CSE4, Scer\HHT2" "Cele\his-27, Cele\his-17, Cele\his-13, Cele\his-74, Cele\his-9, Cele\his-55, Cele\his-25, Cele\his-2, Cele\his-71, Cele\his-42, Cele\his-32, Cele\his-49, Cele\his-72, Cele\his-45, Cele\his-59, Cele\his-6, Cele\his-63, Cele\his-69" "Xtro\cenpa, Xtro\LOC100485665, Xtro\LOC101731144, Xtro\hist2h3d, Xtro\h3f3b, Xtro\LOC100496129" "Mmus\Hist1h3e, Mmus\Hist2h3b, Mmus\Hist1h3i, Mmus\Hist1h3f, Mmus\Hist1h3h, Mmus\Hist1h3a, Mmus\Hist1h3g, Mmus\Cenpa, Mmus\H3f3a, Mmus\Hist1h3c, Mmus\Hist2h3c1, Mmus\Hist2h3c2, Mmus\Hist1h3d, Mmus\Hist1h3b, Mmus\H3f3b" "Hsap\CENPA, Hsap\HIST1H3J, Hsap\HIST2H3A, Hsap\H3F3B, Hsap\HIST1H3A, Hsap\HIST1H3G, Hsap\HIST1H3D, Hsap\HIST1H3B, Hsap\HIST1H3H, Hsap\HIST1H3C, Hsap\HIST1H3I, Hsap\HIST3H3, Hsap\HIST1H3E, Hsap\H3F3C, Hsap\H3F3A, Hsap\HIST2H3D, Hsap\HIST1H3F, Hsap\HIST2H3C" FBgn0053854 His3:CG33854 His3:CG33854 http://flybase.org/reports/FBgn0053854 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33854, His3:CG33854" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33854 11-Aug-17 DroID_v2017_08 "Drer\h3f3a, Drer\h3f3d, Drer\si:ch73-36p18.2, Drer\h3f3c, Drer\si:ch1073-429i10.3, Drer\zgc:113983, Drer\hist2h3c, Drer\LOC108190746, Drer\LOC108190747, Drer\zgc:113984, Drer\cenpa, Drer\hist2h3ca1, Drer\zgc:173552, Drer\h3f3b.1" "Scer\HHT1, Scer\CSE4, Scer\HHT2" "Cele\his-55, Cele\his-45, Cele\his-27, Cele\his-63, Cele\his-71, Cele\his-49, Cele\his-2, Cele\his-42, Cele\his-9, Cele\his-69, Cele\his-25, Cele\his-72, Cele\his-13, Cele\his-32, Cele\his-74, Cele\his-59, Cele\his-17, Cele\his-6" "Xtro\h3f3b, Xtro\cenpa, Xtro\LOC100494884, Xtro\hist2h3d" "Mmus\Hist1h3b, Mmus\H3f3b, Mmus\Hist1h3d, Mmus\Hist1h3h, Mmus\Hist2h3c2, Mmus\Hist1h3e, Mmus\Hist1h3a, Mmus\Hist2h3c1, Mmus\Hist1h3i, Mmus\Hist2h3b, Mmus\Cenpa, Mmus\H3f3a, Mmus\Hist1h3f, Mmus\Hist1h3c, Mmus\Hist1h3g" "Hsap\HIST1H3F, Hsap\HIST1H3D, Hsap\HIST1H3A, Hsap\CENPA, Hsap\HIST1H3H, Hsap\HIST1H3I, Hsap\H3F3A, Hsap\HIST2H3A, Hsap\HIST1H3J, Hsap\HIST2H3D, Hsap\HIST1H3G, Hsap\HIST1H3C, Hsap\H3F3B, Hsap\HIST3H3, Hsap\HIST2H3C, Hsap\HIST1H3B, Hsap\HIST1H3E, Hsap\H3F3C" FBgn0053893 His4:CG33893 His4:CG33893 http://flybase.org/reports/FBgn0053893 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33893, His4:CG33893" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33893 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-261m9.18, Drer\hist1h4l, Drer\si:ch73-36p18.3, Drer\si:ch73-36p18.4, Drer\LOC570405, Drer\si:ch73-368j24.1, Drer\LOC100150038, Drer\LOC794549, Drer\si:dkey-108k21.19, Drer\LOC100331412, Drer\LOC100329358, Drer\si:ch211-113a14.26, Drer\si:dkey-261m9.17, Drer\si:dkey-108k21.28, Drer\si:ch211-113a14.6, Drer\zgc:154164, Drer\si:dkey-23a13.14, Drer\si:ch211-113a14.17, Drer\si:dkey-23a13.7, Drer\si:ch73-368j24.14, Drer\LOC562770, Drer\zgc:163040, Drer\zgc:194989, Drer\zgc:153409, Drer\si:dkey-108k21.12" "Scer\HHF1, Scer\HHF2" "Cele\his-56, Cele\his-10, Cele\his-37, Cele\his-50, Cele\his-67, Cele\his-60, Cele\his-64, Cele\his-28, Cele\his-38, Cele\his-31, Cele\his-18, Cele\his-46, Cele\his-26, Cele\his-5, Cele\his-1, Cele\his-14" "Xtro\LOC100493041, Xtro\hist1h4k, Xtro\hist1h4c" "Mmus\Hist1h4d, Mmus\Hist1h4c, Mmus\Hist1h4h, Mmus\Hist1h4b, Mmus\Hist2h4, Mmus\Hist4h4, Mmus\Hist1h4j, Mmus\Hist1h4m, Mmus\Hist1h4a, Mmus\Hist1h4k, Mmus\Hist1h4n, Mmus\Hist1h4f, Mmus\Hist1h4i" "Hsap\HIST4H4, Hsap\HIST1H4A, Hsap\HIST1H4E, Hsap\HIST1H4D, Hsap\HIST1H4H, Hsap\HIST1H4C, Hsap\HIST1H4B, Hsap\HIST2H4B, Hsap\HIST2H4A, Hsap\HIST1H4L, Hsap\HIST1H4J, Hsap\HIST1H4G, Hsap\HIST1H4K, Hsap\HIST1H4I, Hsap\HIST1H4F, Hsap\HIST1H2AI" FBgn0011715 Snr1 Snf5-related 1 http://flybase.org/reports/FBgn0011715 FBgn0010744 protein_coding_gene SET domain binding ; GO:0070984 | inferred from physical interaction with trx transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 protein binding ; GO:0005515 | inferred from physical interaction with brm inferred from physical interaction with CycE inferred from physical interaction with Rbf "muscle organ development ; GO:0007517 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000001217 epidermis development ; GO:0008544 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype ATP-dependent chromatin remodeling ; GO:0043044 | inferred from biological aspect of ancestor with PANTHER:PTN000001217 ATP-dependent chromatin remodeling ; GO:0043044 | inferred from sequence or structural similarity with SGD:S000005816 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype nucleosome disassembly ; GO:0006337 | inferred from biological aspect of ancestor with PANTHER:PTN000001217 imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with SGD:S000005816" nuclear chromosome ; GO:0000228 | inferred from electronic annotation with InterPro:IPR006939 PBAF complex ; GO:0070604 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay brahma complex ; GO:0035060 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "SNR1, BAP45, snr1, Snr1/BAP45, snr, l(3)01319, CG1064, Snr1, Snr, snr-1, Snr-1" "IPR006939:SNF5/SMARCB1/INI1, IPR017393:SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1" CG1064 11-Aug-17 DroID_v2017_08 "Drer\smarcb1b, Drer\smarcb1a" "Scer\SNF5, Scer\SFH1" Cele\snfc-5 Xtro\smarcb1 Mmus\Smarcb1 Hsap\SMARCB1 " embryonic stage--pupal stage , adult stage | female , embryonic stage -- adult stage ," unfertilized egg

" embryonic stage | early , embryonic stage | stage >=13 , larval stage | third instar , larval stage , adult stage | female , embryonic stage--pupal stage " "

ubiquitous , embryonic brain

, larval optic lobe | restricted

, imaginal disc

, embryonic/larval salivary gland

, dorsal mesothoracic disc | restricted

, larval salivary gland

, embryonic central nervous system

, eye disc

, germarium region 2 && germarium region 3

, ventral thoracic disc | restricted

" "lethal - all die before end of second instar larval stage,hyperplasia,lethal - all die before end of P-stage,lethal,recessive,lethal - all die before end of embryonic stage,neuroanatomy defective,cell shape defective,lethal - all die before end of larval stage,some die during larval stage,suppressor of variegation,dominant,heat sensitive,visible,short lived,female sterile,cell lethalcell lethal,somatic clone,germline clone,body color defective,large body,viable,non-enhancer of variegation,non-suppressor of variegation,increased cell size,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval brain,adult antennal lobe projection neuron DL1 adPN,tergite,wing,wing vein,ectopic,mechanosensory chaeta & adult abdomen | somatic clone,mechanosensory chaeta | supernumerary & adult abdomen | somatic clone,socket & adult abdomen | somatic clone,adult cuticle,somatic clone,eye,adult thorax | dorsal & chaeta | somatic clone,heat sensitive,wing vein L2,wing sensillum,wing margin,wing hair,type II neuroblast,supernumerary" FBgn0025729 tra2::Hsap\SRSF2 SFRS2 http://flybase.org/reports/FBgn0025729 - engineered_fusion_gene - - - "TRA-2/SC35, tra2::Hsap\SFRS2, tra2::Hsap\SRSF2" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0042168 CG18848 - http://flybase.org/reports/FBgn0042168 protein_coding_gene - - - CG18848 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0040908 CG12687 - http://flybase.org/reports/FBgn0040908 protein_coding_gene - - - CG12687 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0263631 mir-3645 mir-3645 stem loop http://flybase.org/reports/FBgn0263631 miRNA_gene - - - "mir-3645, CR43525" - CR43525 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0030067 Rbm13 RNA-binding motif protein 13 http://flybase.org/reports/FBgn0030067 protein_coding_gene - maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000600976 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000600976 "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000600976 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000600976" "Rbm13, CG10648, RBM13" "IPR006958:Mak16 protein, IPR029004:Ribosomal L28e/Mak16" CG10648 11-Aug-17 DroID_v2017_08 Drer\mak16 Scer\MAK16 Cele\C16A3.6 Xtro\mak16 Mmus\Mak16 Hsap\MAK16 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0003961 Uro Urate oxidase http://flybase.org/reports/FBgn0003961 FBgn0044662 protein_coding_gene urate oxidase activity ; GO:0004846 | inferred from electronic annotation with InterPro:IPR019842 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR019842 purine nucleobase metabolic process ; GO:0006144 | inferred from electronic annotation with InterPro:IPR019842 allantoin biosynthetic process ; GO:0019428 | traceable author statement response to ethanol ; GO:0045471 | inferred from mutant phenotype peroxisome ; GO:0005777 | inferred from sequence or structural similarity with RGD:621369 inferred from sequence model "UOX, uro, UO, Dm UO, OU, Uo, CG7171, anon-WO0140519.210, Uro" "IPR002042:Uricase, IPR019842:Uricase, conserved site" CG7171 11-Aug-17 DroID_v2017_08 Drer\uox - - Xtro\uox Mmus\Uox - " larval stage , larval stage | third instar , adult stage " Malpighian tubule

larval stage | third instar Malpighian tubule

"viable,fertile" FBgn0036738 CG7542 - http://flybase.org/reports/FBgn0036738 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP71, CG7542" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG7542 11-Aug-17 DroID_v2017_08 "Drer\zgc:112302, Drer\masp2, Drer\zgc:92041, Drer\ela3l, Drer\zgc:92745, Drer\zgc:112368, Drer\zgc:112285" - "Cele\svh-1, Cele\try-4" - "Mmus\Cela2a, Mmus\Cela1, Mmus\Ctrc, Mmus\Cela3a, Mmus\Ctrl, Mmus\Ctrb1, Mmus\Cela3b" - viable DRSC10868 K 0.039255786 0.028356441 -0.212517686 0.422996093 1.592518254 2.211284358 FBgn0036411 Sox21a Sox21a http://flybase.org/reports/FBgn0036411 protein_coding_gene - stem cell proliferation ; GO:0072089 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of cell differentiation ; GO:0045596 | inferred from mutant phenotype enterocyte differentiation ; GO:1903703 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Sox B2-3, CG7345, SOXB2.3, SoxB2.3, Sox21a, Sox21" IPR009071:High mobility group box domain CG7345 11-Aug-17 DroID_v2017_08 "Drer\sox1a, Drer\sox3, Drer\tcf7l1b, Drer\sox18, Drer\sox11a, Drer\sox21b, Drer\sox21a, Drer\sox14, Drer\tcf7l1a, Drer\lef1, Drer\sox11b, Drer\sox17, Drer\sox4a, Drer\sox7, Drer\sox8a, Drer\sox4b, Drer\LOC103910042, Drer\sox1b, Drer\sox2, Drer\sox12, Drer\sox19b" Scer\ROX1 "Cele\sox-2, Cele\sem-2, Cele\sox-4, Cele\sox-3" "Xtro\sox1, Xtro\sox18, Xtro\sox17b.2, Xtro\sox2, Xtro\sox17b.1, Xtro\sox3, Xtro\sox14, Xtro\sox21, Xtro\sox7, Xtro\sox17a" "Mmus\Sox21, Mmus\Sox17, Mmus\Sox9, Mmus\Sox1, Mmus\Sox11, Mmus\Sox3, Mmus\Sox12, Mmus\Sox2, Mmus\Sox8, Mmus\Sox14, Mmus\Sox7, Mmus\Sox4, Mmus\Sox18" "Hsap\SOX4, Hsap\SOX1, Hsap\SOX7, Hsap\SOX14, Hsap\SOX3, Hsap\SOX18, Hsap\SOX2, Hsap\SOX11, Hsap\SOX17, Hsap\SOX12, Hsap\SOX21" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC10819 K -0.716720598 -0.281352836 -0.747475334 1.388741686 0.046036817 1.590380703 FBgn0004868 Gdi GDP dissociation inhibitor http://flybase.org/reports/FBgn0004868 "FBgn0010224, FBgn0014258" protein_coding_gene Rab GDP-dissociation inhibitor activity ; GO:0005093 | inferred from electronic annotation with InterPro:IPR000806 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 GDP-dissociation inhibitor activity ; GO:0005092 | inferred from direct assay oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR000806 small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR018203 neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay synaptic vesicle ; GO:0008021 | non-traceable author statement "CG4422, GDI, N7-3, dGDI, rab GDI, l(2)N7-3, GdI, Gdi, lincRNA.S746" "IPR018203:GDP dissociation inhibitor, IPR000806:Rab GDI protein, IPR023753:FAD/NAD(P)-binding domain" CG4422 11-Aug-17 DroID_v2017_08 "Drer\gdi1, Drer\gdi2, Drer\zgc:112334" "Scer\MRS6, Scer\GDI1" Cele\gdi-1 "Xtro\gdi1, Xtro\gdi2" "Mmus\Gdi1, Mmus\Gdi2" "Hsap\GDI1, Hsap\GDI2" "lethal,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "pole cell,embryonic epidermis,germline clone,puparium,melanotic mass,trichogen cell,mesothoracic tergum" FBgn0030474 CG15747 - http://flybase.org/reports/FBgn0030474 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG15747 IPR018612:Domain of unknown function DUF2040 CG15747 11-Aug-17 DroID_v2017_08 Drer\nsrp1 - Cele\ccdc-55 - Mmus\Nsrp1 Hsap\NSRP1 FBgn0037341 CG12746 - http://flybase.org/reports/FBgn0037341 protein_coding_gene phosphatidate phosphatase activity ; GO:0008195 | inferred from sequence or structural similarity with SGD:S000002911 phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000017950 phosphatidate phosphatase activity ; GO:0008195 | non-traceable author statement dephosphorylation ; GO:0016311 | non-traceable author statement phospholipid dephosphorylation ; GO:0046839 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 phospholipid metabolic process ; GO:0006644 | inferred from sequence or structural similarity with SGD:S000002911 phospholipid metabolic process ; GO:0006644 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 membrane ; GO:0016020 | inferred from sequence or structural similarity with SGD:S000002911 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 "WUN-like, CG12746" "IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase, IPR032462:Phosphatidate phosphatase PPAPDC1B" CG12746 11-Aug-17 DroID_v2017_08 "Drer\plpp5, Drer\plpp3, Drer\LOC571722, Drer\LOC794598, Drer\plppr1, Drer\ppap2d, Drer\plpp2b, Drer\plpp4, Drer\plppr2a, Drer\plppr3b, Drer\plpp2a" "Scer\DPP1, Scer\LPP1" "Cele\F13E6.5, Cele\T28D9.3, Cele\F53C3.13" "Xtro\plpp5, Xtro\plpp4, Xtro\plpp3, Xtro\plpp1, Xtro\plpp2" "Mmus\Plppr2, Mmus\Plpp5, Mmus\Plpp2, Mmus\Plpp3, Mmus\Plpp1, Mmus\Plpp4" "Hsap\PLPP3, Hsap\PLPP5, Hsap\PLPP2, Hsap\PLPP4, Hsap\PLPP1, Hsap\PLPPR2" "viable,fertile" FBgn0053897 His4:CG33897 His4:CG33897 http://flybase.org/reports/FBgn0053897 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33897, His4:CG33897" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33897 11-Aug-17 DroID_v2017_08 "Drer\zgc:163040, Drer\LOC562770, Drer\hist1h4l, Drer\si:dkey-23a13.7, Drer\si:dkey-108k21.19, Drer\LOC100150038, Drer\si:ch73-368j24.14, Drer\LOC794549, Drer\si:dkey-108k21.12, Drer\si:ch211-113a14.17, Drer\si:dkey-108k21.28, Drer\zgc:194989, Drer\si:ch211-113a14.26, Drer\si:dkey-261m9.17, Drer\zgc:154164, Drer\si:ch211-113a14.6, Drer\LOC570405, Drer\LOC100331412, Drer\si:ch73-36p18.4, Drer\si:ch73-368j24.1, Drer\si:dkey-261m9.18, Drer\LOC100329358, Drer\zgc:153409, Drer\si:ch73-36p18.3" "Scer\HHF1, Scer\HHF2" "Cele\his-18, Cele\his-38, Cele\his-60, Cele\his-46, Cele\his-26, Cele\his-37, Cele\his-5, Cele\his-14, Cele\his-1, Cele\his-31, Cele\his-67, Cele\his-50, Cele\his-10, Cele\his-28, Cele\his-56, Cele\his-64" "Xtro\hist1h4a, Xtro\hist1h4k, Xtro\hist1h4c, Xtro\LOC100493041" "Mmus\Hist4h4, Mmus\Hist1h4i, Mmus\Hist1h4j, Mmus\Hist1h4d, Mmus\Hist1h4f, Mmus\Hist1h4k, Mmus\Hist1h4n, Mmus\Hist1h4m, Mmus\Hist1h4a, Mmus\Hist1h4c, Mmus\Hist1h4b, Mmus\Hist2h4, Mmus\Hist1h4h" "Hsap\HIST1H4K, Hsap\HIST1H4B, Hsap\HIST1H4J, Hsap\HIST1H4L, Hsap\HIST1H4H, Hsap\HIST1H4A, Hsap\HIST1H4D, Hsap\HIST1H4I, Hsap\HIST1H4F, Hsap\HIST2H4B, Hsap\HIST1H4C, Hsap\HIST2H4A, Hsap\HIST4H4, Hsap\HIST1H4G, Hsap\HIST1H4E" DRSC30020 IEK -3.179513886 -3.964253834 -1.486507778 -5.104496797 -2.504067021 0.541527032 FBgn0036813 Atg3 Autophagy-related 3 http://flybase.org/reports/FBgn0036813 protein_coding_gene Atg8 ligase activity ; GO:0019776 | inferred from sequence or structural similarity with SGD:S000005290 ubiquitin-like protein transferase activity ; GO:0019787 | inferred from sequence or structural similarity with HGNC:20962 Atg8 ligase activity ; GO:0019776 | inferred from biological aspect of ancestor with PANTHER:PTN000305308 autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000305308 glycophagy ; GO:0061723 | inferred from mutant phenotype nucleophagy ; GO:0044804 | inferred from biological aspect of ancestor with PANTHER:PTN000305308 mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000305308 larval midgut cell programmed cell death ; GO:0035096 | NOT inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype cytoplasmic ubiquitin ligase complex ; GO:0000153 | inferred from biological aspect of ancestor with PANTHER:PTN000305308 cytosol ; GO:0005829 | inferred from direct assay "Atg3, Draut1, CG6877, Aut1, atg3, Aut-1, AUT1, dAtg3" "IPR007134:Autophagy-related protein 3, N-terminal, IPR007135:Autophagy-related protein 3, IPR019461:Autophagy-related protein 3, C-terminal" CG6877 11-Aug-17 DroID_v2017_08 Drer\atg3 Scer\ATG3 Cele\atg-3 Xtro\atg3 Mmus\Atg3 Hsap\ATG3 "viable,partially lethal - majority die,heat sensitive,lethal,fertile" "autophagic vacuole,embryonic/larval fat body" DRSC29687 K -0.541232223 0.371725853 0.645217718 -0.026466699 0.311136432 1.705667528 FBgn0030028 Corp Companion of reaper http://flybase.org/reports/FBgn0030028 protein_coding_gene p53 binding ; GO:0002039 | inferred from physical interaction with p53 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ; GO:1902166 | inferred from genetic interaction with p53 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage ; GO:1902230 | inferred from mutant phenotype - "CG10965, Corp, corp" - CG10965 11-Aug-17 DroID_v2017_08 - - - - - - pupal stage salivary gland

"partially lethal - majority die,some die during pupal stage" DRSC17771 K -0.643252825 -0.397576893 -0.510746001 -0.089154985 1.778323333 0.604168559 FBgn0259143 CG42258 - http://flybase.org/reports/FBgn0259143 protein_coding_gene - - plasma membrane ; GO:0005886 | inferred from direct assay "CG42258, BcDNA:RE29468, CG15926, CG17788, Pripl4" - CG42258 11-Aug-17 DroID_v2017_08 - - - - - - DRSC19741 E 1.389771436 1.430670765 1.553865835 1.077260489 0.638831854 -0.241470646 FBgn0026084 cib ciboulot http://flybase.org/reports/FBgn0026084 - protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity actin monomer binding ; GO:0003785 | inferred from direct assay actin filament organization ; GO:0007015 | inferred from electronic annotation with InterPro:IPR001152 larval central nervous system remodeling ; GO:0035193 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG4944, EG0007-11, EG:EG0007.11, cib" IPR001152:Beta-thymosin CG4944 11-Aug-17 DroID_v2017_08 "Drer\tmsb4x, Drer\tmsb" - Cele\tth-1 Xtro\tmsb4x "Mmus\Tmsb15a, Mmus\Tmsb15b1, Mmus\Tmsb15b2, Mmus\Tmsb15l, Mmus\Tmsb10, Mmus\Tmsb4x" "Hsap\TMSB4X, Hsap\TMSB4Y, Hsap\TMSB10, Hsap\TMSB15A, Hsap\TMSB15B" "viable,body color defective" "ellipsoid body,mushroom body beta-lobe,mesothoracic tergum" DRSC18660 K -0.143367977 0.425297082 -0.110915794 0.227366776 -0.025248372 -2.979034378 FBgn0262560 wcd wicked http://flybase.org/reports/FBgn0262560 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000427904 neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype rRNA processing ; GO:0006364 | inferred from mutant phenotype" Pwp2p-containing subcomplex of 90S preribosome ; GO:0034388 | inferred from biological aspect of ancestor with PANTHER:PTN000427904 nucleus ; GO:0005634 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000427904 germinal vesicle ; GO:0042585 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from physical interaction with snoRNA:U3:9B inferred from physical interaction with snoRNA:U3:54Ab inferred from physical interaction with snoRNA:U3:54Aa "CG7989, wcd, l(2)k07824, wicked, l(2)kO7824, Wcd" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat" CG7989 11-Aug-17 DroID_v2017_08 Drer\utp18 Scer\UTP18 Cele\B0280.9 Xtro\utp18 Mmus\Utp18 "Hsap\UTP18, Hsap\WDSUB1" DRSC07051 K -0.292753859 0.234427536 -0.112888853 0.140663539 -0.525729232 1.548139505 FBgn0053907 His4:CG33907 His4:CG33907 http://flybase.org/reports/FBgn0053907 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33907, His4:CG33907" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33907 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.19, Drer\LOC570405, Drer\si:ch73-368j24.14, Drer\si:dkey-108k21.28, Drer\si:ch211-113a14.6, Drer\hist1h4l, Drer\si:dkey-261m9.17, Drer\LOC100150038, Drer\zgc:194989, Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.17, Drer\si:dkey-108k21.12, Drer\LOC562770, Drer\LOC794549, Drer\si:ch73-36p18.3, Drer\LOC100331412, Drer\zgc:153409, Drer\si:ch73-36p18.4, Drer\zgc:163040, Drer\si:ch73-368j24.1, Drer\si:ch211-113a14.26, Drer\zgc:154164, Drer\si:dkey-261m9.18, Drer\LOC100329358" "Scer\HHF1, Scer\HHF2" "Cele\his-67, Cele\his-5, Cele\his-31, Cele\his-60, Cele\his-10, Cele\his-56, Cele\his-46, Cele\his-18, Cele\his-50, Cele\his-1, Cele\his-64, Cele\his-38, Cele\his-37, Cele\his-14, Cele\his-26, Cele\his-28" "Xtro\hist1h4c, Xtro\hist1h4k, Xtro\LOC100493041, Xtro\LOC101733182" "Mmus\Hist1h4b, Mmus\Hist2h4, Mmus\Hist4h4, Mmus\Hist1h4c, Mmus\Hist1h4f, Mmus\Hist1h4i, Mmus\Hist1h4a, Mmus\Hist1h4k, Mmus\Hist1h4d, Mmus\Hist1h4n, Mmus\Hist1h4m, Mmus\Hist1h4j, Mmus\Hist1h4h" "Hsap\HIST2H4A, Hsap\HIST1H4C, Hsap\HIST1H4H, Hsap\HIST1H4B, Hsap\HIST1H4E, Hsap\HIST1H4K, Hsap\HIST1H4F, Hsap\HIST1H4D, Hsap\HIST1H4G, Hsap\HIST1H4A, Hsap\HIST1H4J, Hsap\HIST2H4B, Hsap\HIST1H4I, Hsap\HIST1H4L, Hsap\HIST4H4" FBgn0010435 emp epithelial membrane protein http://flybase.org/reports/FBgn0010435 - protein_coding_gene receptor activity ; GO:0004872 | inferred from electronic annotation with InterPro:IPR005429 autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern lysosome ; GO:0005764 | inferred from electronic annotation with InterPro:IPR005429 plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:1665 inferred from sequence or structural similarity with protein_id:AAA41531.1 "CG2727, emp" "IPR002159:CD36 family, IPR005428:CD36/scavenger receptor class B member 1, IPR005429:Lysosome membrane protein II" CG2727 11-Aug-17 DroID_v2017_08 "Drer\scarb1, Drer\cd36, Drer\scarb2, Drer\LOC564077" - "Cele\scav-2, Cele\scav-6, Cele\scav-3, Cele\scav-1" "Xtro\cd36, Xtro\scarb1, Xtro\scarb2" "Mmus\Scarb1, Mmus\Scarb2, Mmus\Cd36" "Hsap\CD36, Hsap\SCARB2, Hsap\SCARB1" " pupal stage | early , embryonic stage | >=6 hr , larval stage | third instar , embryonic stage | stage 13 " " imaginal disc

, embryonic/larval hindgut | restricted

, embryonic/larval foregut | restricted

, peripodial epithelium &&of dorsal mesothoracic disc

, dorsal mesothoracic disc | restricted

, ectoderm

, epidermis

, embryonic/larval tracheal system

" viable FBgn0019928 Ser8 Ser8 http://flybase.org/reports/FBgn0019928 FBgn0033838 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type peptidase activity ; GO:0008236 | inferred from sequence or structural similarity "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP90, CG4812, SP#3, SP3, Ser8" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG4812 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.9, Drer\prss60.1, Drer\zgc:112160, Drer\tmprss4b, Drer\prss60.3, Drer\LOC562139, Drer\zgc:55888, Drer\ctrl, Drer\prss60.2, Drer\zgc:153968, Drer\zgc:92590, Drer\zgc:123295, Drer\try, Drer\si:dkeyp-93a5.2, Drer\zgc:112038, Drer\zgc:163079, Drer\si:ch211-165b19.8" - "Cele\rab-11.1, Cele\try-1, Cele\svh-1" - "Mmus\Prss1, Mmus\Prss55, Mmus\Gm5771, Mmus\Prss36, Mmus\Prss2, Mmus\Gzmm, Mmus\Gm10334, Mmus\2210010C04Rik, Mmus\Try4, Mmus\Try10, Mmus\Prss53, Mmus\Prss34, Mmus\Prss3" "Hsap\PRSS53, Hsap\GZMM, Hsap\PRSS36, Hsap\PRSS3, Hsap\PRSS1" viable FBgn0031238 CG3645 - http://flybase.org/reports/FBgn0031238 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517 tRNA dihydrouridine synthase activity ; GO:0017150 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517" - CG3645 "IPR018517:tRNA-dihydrouridine synthase, conserved site, IPR001269:tRNA-dihydrouridine synthase, IPR013785:Aldolase-type TIM barrel" CG3645 11-Aug-17 DroID_v2017_08 "Drer\dus4l, Drer\dus1l" "Scer\DUS1, Scer\DUS4" Cele\F36A2.2 "Xtro\dus1l, Xtro\dus4l" "Mmus\Dus1l, Mmus\Dus4l" "Hsap\DUS1L, Hsap\DUS4L" "viable,fertile" FBgn0026147 CG16833 - http://flybase.org/reports/FBgn0026147 FBgn0032327 protein_coding_gene - protein polyglutamylation ; GO:0018095 | inferred from electronic annotation with InterPro:IPR027748 wound healing ; GO:0042060 | inferred from mutant phenotype - "LD13681, BEST:LD13681, CG16833" "IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027748:Tubulin polyglutamylase TTLL-4" CG16833 11-Aug-17 DroID_v2017_08 "Drer\ttll5, Drer\ttll4" - "Cele\ttll-5, Cele\ttll-4" Xtro\ttll4 "Mmus\Ttll5, Mmus\Ttll4" "Hsap\TTLL5, Hsap\TTLL4" viable FBgn0031910 CG15818 - http://flybase.org/reports/FBgn0031910 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - CG15818 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG15818 11-Aug-17 DroID_v2017_08 "Drer\hbl3, Drer\colec12, Drer\hbl2, Drer\colec11" - "Cele\F52E1.2, Cele\clec-149, Cele\clec-178" Xtro\colec10 "Mmus\Fcer2a, Mmus\Cd207, Mmus\Asgr2, Mmus\Clec1b, Mmus\Mgl2, Mmus\Asgr1, Mmus\Clec10a" "Hsap\COLEC11, Hsap\CLEC4A, Hsap\MBL2, Hsap\CLEC1B, Hsap\SFTPD, Hsap\SFTPA1, Hsap\SFTPA2, Hsap\CLEC7A, Hsap\COLEC10" "viable,visible" "trichogen cell,supernumerary,tormogen cell" FBgn0053851 His3:CG33851 His3:CG33851 http://flybase.org/reports/FBgn0053851 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33851, His3:CG33851" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33851 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-36p18.2, Drer\zgc:113983, Drer\LOC108190747, Drer\si:ch1073-429i10.3, Drer\hist2h3ca1, Drer\h3f3a, Drer\h3f3b.1, Drer\cenpa, Drer\si:dkey-23a13.8, Drer\LOC108190746, Drer\zgc:113984, Drer\h3f3d, Drer\hist2h3c, Drer\h3f3c, Drer\zgc:173552" "Scer\HHT1, Scer\HHT2, Scer\CSE4" "Cele\his-13, Cele\his-59, Cele\his-9, Cele\his-49, Cele\his-17, Cele\his-74, Cele\his-71, Cele\his-25, Cele\his-6, Cele\his-55, Cele\his-63, Cele\his-42, Cele\his-2, Cele\his-32, Cele\his-45, Cele\his-72, Cele\his-27, Cele\his-69" "Xtro\hist2h3d, Xtro\LOC100495338, Xtro\cenpa, Xtro\h3f3b" "Mmus\H3f3a, Mmus\Hist1h3e, Mmus\Hist2h3b, Mmus\Hist1h3a, Mmus\Hist1h3c, Mmus\Hist2h3c1, Mmus\Hist2h3c2, Mmus\Hist1h3i, Mmus\Hist1h3g, Mmus\Hist1h3d, Mmus\H3f3b, Mmus\Hist1h3f, Mmus\Hist1h3b, Mmus\Hist1h3h, Mmus\Cenpa" "Hsap\H3F3B, Hsap\HIST1H3I, Hsap\HIST2H3D, Hsap\HIST3H3, Hsap\HIST1H3E, Hsap\HIST2H3A, Hsap\HIST1H3F, Hsap\HIST2H3C, Hsap\HIST1H3D, Hsap\H3F3C, Hsap\HIST1H3J, Hsap\HIST1H3H, Hsap\HIST1H3A, Hsap\H3F3A, Hsap\CENPA, Hsap\HIST1H3C, Hsap\HIST1H3G, Hsap\HIST1H3B" FBgn0010501 Dcp-1 Death caspase-1 http://flybase.org/reports/FBgn0010501 FBgn0010509 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay BIR domain binding ; GO:1990525 | inferred from physical interaction with Diap1 cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity inferred from direct assay cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:0097200 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with Diap1 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001309, InterPro:IPR002138, InterPro:IPR011600, InterPro:IPR016129 positive regulation of macroautophagy ; GO:0016239 | inferred from mutant phenotype programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern nurse cell apoptotic process ; GO:0045476 | traceable author statement actin filament organization ; GO:0007015 | traceable author statement apoptotic process ; GO:0006915 | inferred from direct assay positive regulation of autophagy ; GO:0010508 | inferred from direct assay neuron remodeling ; GO:0016322 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | traceable author statement nurse cell apoptotic process ; GO:0045476 | inferred from genetic interaction with Drice cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype multicellular organism development ; GO:0007275 | traceable author statement programmed cell death ; GO:0012501 | inferred from direct assay cellular response to starvation ; GO:0009267 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern execution phase of apoptosis ; GO:0097194 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:1508 "dcp-1, Dcp-1, DCP-1, Dcp1, dcp1, DCP1, l(2)02132, l(2)01862, CG5370, ccp1" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR015917:Peptidase C14A, caspase catalytic domain, IPR016129:Peptidase family C14A, His active site, IPR029030:Caspase-like domain, IPR033139:Peptidase family C14A, cysteine active site" CG5370 11-Aug-17 DroID_v2017_08 "Drer\casp6, Drer\casp8, Drer\casp9, Drer\casp3b, Drer\casp8l1, Drer\pea15, Drer\casp2, Drer\caspa, Drer\cflara, Drer\si:ch211-195h23.3, Drer\LOC798445, Drer\caspb, Drer\casp6l1, Drer\casp3a, Drer\si:dkey-103e21.5, Drer\casp6l2, Drer\LOC100331324, Drer\caspxa, Drer\zgc:194469, Drer\LOC101886133, Drer\caspbl, Drer\casp8l2, Drer\zgc:171731, Drer\gbp3, Drer\casp7" - "Cele\ced-3, Cele\csp-1" "Xtro\LOC733553, Xtro\casp10, Xtro\casp6, Xtro\casp2, Xtro\casp1, Xtro\casp9, Xtro\casp3, Xtro\casp7, Xtro\pea15" "Mmus\Cflar, Mmus\Casp7, Mmus\Casp2, Mmus\Casp4, Mmus\Pea15a, Mmus\Casp12, Mmus\Casp1, Mmus\Casp3, Mmus\Casp6, Mmus\Pycard, Mmus\Casp9, Mmus\Casp8, Mmus\Casp14" "Hsap\CASP8, Hsap\CARD16, Hsap\PYCARD, Hsap\CASP7, Hsap\PEA15, Hsap\CARD8, Hsap\CASP1, Hsap\CARD17, Hsap\CASP9, Hsap\CASP2, Hsap\CASP14, Hsap\CASP10, Hsap\CASP6, Hsap\CFLAR, Hsap\CASP5, Hsap\CASP3, Hsap\CASP4, Hsap\CARD18" embryonic stage "increased cell death,cell death defective,neuroanatomy defective,neurophysiology defective,viable,visible,eye color defective,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell death,nutrition conditional,sterile" "egg chamber,follicle cell,neuron,eye,pigment cell,conditional,chaeta,supernumerary,eye disc,dendrite,germarium region 2,nutrition conditional,female germline cyst,spermatogonial cyst,male germline cell,actin filament & nurse cellnos.UTR.THsimVP16,outer photoreceptor cell" FBgn0028369 kirre kin of irre http://flybase.org/reports/FBgn0028369 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with rols cell adhesion molecule binding ; GO:0050839 | inferred from physical interaction with pyd nephrocyte filtration ; GO:0097206 | inferred from mutant phenotype nephrocyte diaphragm assembly ; GO:0036059 | inferred from mutant phenotype regulation of striated muscle tissue development ; GO:0016202 | inferred from mutant phenotype inferred from genetic interaction with rst compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype garland nephrocyte differentiation ; GO:0061321 | inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | traceable author statement homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from genetic interaction with sns filtration diaphragm assembly ; GO:0036058 | inferred from mutant phenotype larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from mutant phenotype regulation of myoblast fusion ; GO:1901739 | inferred from mutant phenotype nephrocyte diaphragm ; GO:0005917 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay "Duf, duf, DUF, Duf/Kirre, DUF/KIRRE, CT12279, EG:163A10.1, CG3653, kirre, Kirre, duf/kirre, RH09239" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003598:Immunoglobulin subtype 2" CG3653 11-Aug-17 DroID_v2017_08 "Drer\kirrel3a, Drer\lrit1b, Drer\ush2a, Drer\kirrela, Drer\dscama, Drer\lrit3a, Drer\itgb4, Drer\sdk1a, Drer\lrit3b, Drer\igsf9bb, Drer\kirrel3b, Drer\tmigd1, Drer\si:ch1073-459j12.1, Drer\igsf9a, Drer\lrit1a, Drer\sdk1b, Drer\ncam1b, Drer\kirrelb, Drer\kirrel3l, Drer\paplna" - Cele\syg-1 "Xtro\papln, Xtro\igsf9b, Xtro\lrit3, Xtro\kirrel2" "Mmus\Lrit1, Mmus\Ptprq, Mmus\Papln, Mmus\Kirrel, Mmus\Kirrel2, Mmus\Sdk1, Mmus\Kirrel3, Mmus\Lrit3, Mmus\Igsf9b" "Hsap\LRIT3, Hsap\SDK1, Hsap\KIRREL2, Hsap\LRIT1, Hsap\KIRREL, Hsap\KIRREL3, Hsap\USH2A, Hsap\IGSF9B, Hsap\PAPLN" "viable,fertile,visible,lethal,male fertile" "embryonic/larval garland cell,pericardial cell,filtration diaphragm,nucleus | supernumerary | third instar larval stage,wing margin,wing hair,embryonic/larval pericardial cell,myoblast,embryonic/larval garland cell | third instar larval stage,nucleus | supernumerary | third instar larval stagepros.PMG,eye,optic lobe,nucleus | supernumerarykirre.PR,ventral acute muscle 2,segment border muscle,ommatidium,inter-ommatidial cell,inter-ommatidial precursor cell,interommatidial bristle" FBgn0053848 His3:CG33848 His3:CG33848 http://flybase.org/reports/FBgn0053848 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33848, His3:CG33848" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33848 11-Aug-17 DroID_v2017_08 "Drer\hist2h3c, Drer\LOC108190746, Drer\hist2h3ca1, Drer\h3f3d, Drer\h3f3b.1, Drer\zgc:113984, Drer\h3f3c, Drer\h3f3a, Drer\si:ch73-36p18.2, Drer\si:ch1073-429i10.3, Drer\zgc:113983, Drer\cenpa, Drer\si:dkey-261m9.8, Drer\si:dkey-23a13.8, Drer\zgc:173552, Drer\LOC108190747" "Scer\CSE4, Scer\HHT1, Scer\HHT2" "Cele\his-27, Cele\his-17, Cele\his-72, Cele\his-6, Cele\his-59, Cele\his-69, Cele\his-45, Cele\his-63, Cele\his-40, Cele\his-25, Cele\his-74, Cele\his-71, Cele\his-42, Cele\his-55, Cele\his-13, Cele\his-9, Cele\his-49, Cele\his-2, Cele\his-32" "Xtro\cenpa, Xtro\h3f3b, Xtro\LOC100487139, Xtro\hist2h3d, Xtro\h3f3b, Xtro\hist2h3c" "Mmus\Cenpa, Mmus\Hist2h2be, Mmus\Hist1h3e, Mmus\Hist1h3b, Mmus\Hist1h3d, Mmus\Hist2h3c1, Mmus\Hist1h3c, Mmus\Hist2h3c2, Mmus\Hist2h3b, Mmus\Hist1h3i, Mmus\H3f3a, Mmus\Hist1h3h, Mmus\Hist1h3g, Mmus\H3f3b, Mmus\Hist1h3f, Mmus\Hist1h3a" "Hsap\CENPA, Hsap\HIST2H3C, Hsap\H3F3B, Hsap\H3F3C, Hsap\HIST1H3C, Hsap\HIST3H3, Hsap\HIST2H3D, Hsap\HIST1H3G, Hsap\HIST1H3D, Hsap\HIST1H3F, Hsap\HIST1H3I, Hsap\HIST1H3J, Hsap\HIST1H3H, Hsap\HIST1H3B, Hsap\H3F3A, Hsap\HIST2H3A, Hsap\HIST1H3E, Hsap\HIST1H3A" FBgn0053808 His2A:CG33808 His2A:CG33808 http://flybase.org/reports/FBgn0053808 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33808, His2A:CG33808" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33808 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-159d7.11, Drer\si:ch73-368j24.13, Drer\si:dkey-108k21.26, Drer\h2afx, Drer\zgc:110434, Drer\si:ch211-113a14.16, Drer\si:ch211-113a14.26, Drer\si:ch73-368j24.14, Drer\si:dkey-23a13.14, Drer\LOC100148591, Drer\h2afy2, Drer\zgc:195633, Drer\LOC570115, Drer\zgc:173652, Drer\zgc:101846, Drer\si:dkey-261m9.7, Drer\LOC100334934, Drer\zgc:114037, Drer\si:ch211-113a14.7, Drer\si:dkey-23a13.7, Drer\si:dkey-261m9.15, Drer\si:ch1073-159d7.10, Drer\si:dkey-261m9.11, Drer\fbxl6, Drer\zgc:154164, Drer\si:ch211-113a14.19, Drer\si:dkey-108k21.15, Drer\si:dkey-108k21.19, Drer\si:dkey-261m9.18, Drer\si:ch211-113a14.11, Drer\LOC100332229, Drer\si:dkey-23a13.20, Drer\si:ch73-36p18.5" "Scer\HTA1, Scer\HTA2" "Cele\his-12, Cele\his-61, Cele\his-19, Cele\his-68, Cele\his-47, Cele\his-16, Cele\his-53, Cele\his-33, Cele\his-43, Cele\his-51, Cele\his-57, Cele\his-35, Cele\htas-1, Cele\his-7, Cele\his-65, Cele\his-3, Cele\his-30, Cele\his-21" "Xtro\hist1h2am, Xtro\h2afy, Xtro\hist1h2ad, Xtro\h2afj, Xtro\hist1h2ah, Xtro\h2afy2, Xtro\hist1h2aa, Xtro\h2afx, Xtro\hist1h2aj" "Mmus\Hist3h2a, Mmus\Hist1h2aa, Mmus\Hist1h2an, Mmus\H2afy2, Mmus\Hist2h2ac, Mmus\H2al2b, Mmus\Gm14920, Mmus\Hist1h2ak, Mmus\H2afb1, Mmus\H2al2c, Mmus\H2afj, Mmus\Hist2h3c1, Mmus\Hist1h2ac, Mmus\H2al1n, Mmus\Hist1h2ad, Mmus\Hist1h2ap, Mmus\Hist2h2aa2, Mmus\Hist1h2ao, Mmus\Hist1h2ag, Mmus\Hist1h2ae, Mmus\Hist2h2aa1, Mmus\H2afb3, Mmus\Hist1h2ai, Mmus\H2afy, Mmus\Hist1h2ab, Mmus\Hist1h2af, Mmus\Hist2h2ab, Mmus\Hist1h2ah, Mmus\H2afx, Mmus\H2al1j, Mmus\H2afb2" "Hsap\HIST2H2AA4, Hsap\H2AFB2, Hsap\HIST1H2AL, Hsap\HIST1H2AH, Hsap\H2AFB1, Hsap\HIST1H2AD, Hsap\HIST1H2AB, Hsap\HIST1H2AC, Hsap\H2AFY, Hsap\H2AFX, Hsap\HIST1H2AA, Hsap\HIST1H2AE, Hsap\H2AFY2, Hsap\HIST1H2AJ, Hsap\HIST1H2AK, Hsap\HIST1H2AG, Hsap\H2AFB3, Hsap\HIST2H2AB, Hsap\HIST3H2A, Hsap\HIST1H2AM, Hsap\HIST2H2AC, Hsap\HIST1H2AI, Hsap\H2AFJ, Hsap\HIST2H2AA3" FBgn0053838 His2A:CG33838 His2A:CG33838 http://flybase.org/reports/FBgn0053838 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33838, His2A:CG33838" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33838 11-Aug-17 DroID_v2017_08 "Drer\zgc:101846, Drer\si:dkey-108k21.26, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.14, Drer\si:ch73-368j24.15, Drer\si:ch211-113a14.19, Drer\fbxl6, Drer\si:ch1073-153i20.5, Drer\si:dkey-23a13.7, Drer\si:dkey-23a13.20, Drer\si:dkey-261m9.11, Drer\si:dkey-261m9.7, Drer\LOC100148591, Drer\si:dkey-261m9.15, Drer\si:ch211-113a14.7, Drer\si:dkey-261m9.18, Drer\zgc:114037, Drer\LOC100334934, Drer\si:ch1073-159d7.10, Drer\h2afy2, Drer\si:ch211-113a14.26, Drer\zgc:154164, Drer\LOC100332229, Drer\si:ch211-113a14.16, Drer\zgc:173652, Drer\si:ch73-36p18.5, Drer\h2afx, Drer\si:ch73-368j24.14, Drer\si:dkey-108k21.19, Drer\zgc:110434, Drer\LOC570115, Drer\si:ch1073-159d7.9, Drer\si:ch73-368j24.13, Drer\si:dkey-108k21.15, Drer\si:ch1073-159d7.11, Drer\zgc:195633, Drer\zgc:165551" "Scer\HTA1, Scer\HTA2" "Cele\his-53, Cele\his-47, Cele\his-7, Cele\his-61, Cele\his-16, Cele\his-35, Cele\his-57, Cele\his-30, Cele\his-21, Cele\his-3, Cele\his-33, Cele\his-65, Cele\his-68, Cele\his-51, Cele\his-19, Cele\his-12, Cele\htas-1, Cele\his-43" "Xtro\hist1h2aj, Xtro\h2afy, Xtro\hist1h2am, Xtro\hist1h2ad, Xtro\h2afx, Xtro\h2afj, Xtro\hist1h2aa, Xtro\hist1h2ah, Xtro\h2afy2" "Mmus\Hist1h2ab, Mmus\H2al1n, Mmus\Hist1h2ad, Mmus\Hist3h2a, Mmus\H2afb3, Mmus\Hist1h2ao, Mmus\Hist1h2ak, Mmus\H2afj, Mmus\Hist1h2aa, Mmus\H2afy2, Mmus\Hist2h2aa1, Mmus\Hist2h2ab, Mmus\Gm14920, Mmus\H2afx, Mmus\H2afb1, Mmus\Hist1h2an, Mmus\H2al1j, Mmus\Hist2h2aa2, Mmus\H2al2c, Mmus\Hist1h2ae, Mmus\Hist2h2ac, Mmus\Hist1h2ai, Mmus\Hist1h2ap, Mmus\Hist1h2ac, Mmus\H2al2b, Mmus\Hist1h2ag, Mmus\Hist1h2af, Mmus\Hist1h2ah, Mmus\H2afy, Mmus\H2afb2" "Hsap\HIST2H2AB, Hsap\H2AFB2, Hsap\H2AFY, Hsap\HIST1H2AH, Hsap\HIST2H2AA3, Hsap\HIST3H2A, Hsap\HIST1H2AG, Hsap\HIST2H2AC, Hsap\H2AFX, Hsap\H2AFY2, Hsap\HIST1H2AD, Hsap\HIST1H2AA, Hsap\HIST1H2AL, Hsap\H2AFB1, Hsap\HIST1H2AJ, Hsap\HIST1H2AE, Hsap\HIST2H2AA4, Hsap\HIST1H2AI, Hsap\HIST1H2AM, Hsap\HIST1H2AB, Hsap\H2AFJ, Hsap\H2AFB3, Hsap\HIST1H2AC, Hsap\HIST1H2AK" FBgn0053858 His1:CG33858 His1:CG33858 http://flybase.org/reports/FBgn0053858 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33858, His1:CG33858" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33858 11-Aug-17 DroID_v2017_08 "Drer\zgc:110425, Drer\si:ch73-368j24.11, Drer\zgc:163061, Drer\h1m, Drer\h1f0, Drer\si:ch1073-153i20.4, Drer\si:dkey-108k21.21, Drer\LOC569982, Drer\si:dkey-108k21.10, Drer\si:dkey-23a13.17, Drer\si:dkey-261m9.12, Drer\histh1l, Drer\si:ch73-368j24.12, Drer\si:ch1073-159d7.7, Drer\si:ch211-113a14.18, Drer\si:dkey-108k21.14, Drer\h1fx, Drer\zgc:153405, Drer\zgc:110216, Drer\si:dkey-23a13.9, Drer\si:ch211-113a14.24, Drer\si:ch73-36p18.1" Scer\HHO1 "Cele\his-24, Cele\hil-2, Cele\hil-5, Cele\hil-6, Cele\hil-3, Cele\hil-4" - "Mmus\Hist1h1a, Mmus\H1foo, Mmus\Hist1h1e, Mmus\Hils1, Mmus\H1fnt, Mmus\Hist1h1b, Mmus\Hist1h1d, Mmus\H1fx, Mmus\Hist1h1c, Mmus\Hist1h1t" "Hsap\HIST1H1E, Hsap\HIST1H1T, Hsap\H1FOO, Hsap\H1FX, Hsap\HIST1H1D, Hsap\H1F0, Hsap\H1FNT, Hsap\HIST1H1B, Hsap\HIST1H1C, Hsap\HIST1H1A" FBgn0002542 lds lodestar http://flybase.org/reports/FBgn0002542 "FBgn0001050, FBgn0019956, FBgn0037532" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 DNA-dependent ATPase activity ; GO:0008094 | inferred from direct assay "spermatogenesis ; GO:0007283 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype microtubule anchoring at centrosome ; GO:0034454 | inferred from mutant phenotype DNA-templated transcription, termination ; GO:0006353 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Horka, Fs(3)Hor, Fs(3)Horka, DmF2, lod, Fs(3)Sz11, early, NTef2, CG2684, lds, Lds" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2684 11-Aug-17 DroID_v2017_08 "Drer\hltf, Drer\ttf2" "Scer\ULS1, Scer\RAD16, Scer\RAD5" "Cele\F54E12.2, Cele\F19B2.5, Cele\T23H2.3" - "Mmus\Hltf, Mmus\Ttf2" "Hsap\TTF2, Hsap\HLTF" " embryonic stage -- adult stage , oogenesis stage && adult stage | female " ovary

"wild-type,mitotic cell cycle defective,non-rescuable maternal effect,recessive,female sterile,male sterile,lethal,partially lethal - majority die,visible,dominant,meiotic cell cycle defective,paternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,partially" "mitosis & nuclear chromosome & embryo,nucleus | embryonic stage,spindle | embryonic stage,chromatin & mitotic anaphase,trichogen cell,male pronucleus | maternal effect,female pronucleus | maternal effect,centrosome,onion stage spermatid,individualization stage spermatid" FBgn0031065 CG14234 - http://flybase.org/reports/FBgn0031065 protein_coding_gene - - - CG14234 IPR025256:Domain of unknown function DUF4203 CG14234 11-Aug-17 DroID_v2017_08 "Drer\tmem198b, Drer\tmem198a" - - Xtro\tmem198 "Mmus\Tmem198b, Mmus\Tmem198" Hsap\TMEM198 viable FBgn0005649 Rox8 Rox8 http://flybase.org/reports/FBgn0005649 "FBgn0010255, FBgn0010283" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000001128 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0000381 U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity with SGD:S000001128 "CG5422, RRM12, TIAR, ROX8, rox8, DmTIAR, rrm12, Rbp12, Rox8, dTIAR, Rox-8" IPR000504:RNA recognition motif domain CG5422 11-Aug-17 DroID_v2017_08 "Drer\trnau1apb, Drer\rbmx, Drer\tia1l, Drer\tia1, Drer\tial1" "Scer\NAM8, Scer\RNP1, Scer\NGR1, Scer\PUB1, Scer\MRN1" "Cele\tiar-3, Cele\tiar-2, Cele\tiar-1, Cele\T07F10.3" "Xtro\pick1, Xtro\tia1" "Mmus\Trnau1ap, Mmus\Rbmx, Mmus\Tial1, Mmus\Rbmxl2, Mmus\Rbmxl1, Mmus\Tia1" "Hsap\TIAL1, Hsap\TIA1, Hsap\SRSF3, Hsap\TRNAU1AP, Hsap\RBMXL2, Hsap\RBMXL1, Hsap\RBMX" " adult stage | female , larval stage&&pupal stage&&adult stage , embryonic stage | early " "viable,fertile" DRSC16829 I -1.621786838 -0.253857938 -0.203477845 -1.4302837 0.348108194 0.256765805 FBgn0052500 CG32500 - http://flybase.org/reports/FBgn0052500 protein_coding_gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR001075 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001075 "iron-sulfur cluster assembly ; GO:0016226 | inferred from electronic annotation with InterPro:IPR001075, InterPro:IPR017065" - "BcDNA:GM32035, CG18856, CG32500" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001075:NIF system FeS cluster assembly, NifU, C-terminal, IPR014824:Scaffold protein Nfu/NifU, N-terminal, IPR017065:NFU1 iron-sulfur cluster scaffold homologue" CG32500 11-Aug-17 DroID_v2017_08 "Drer\zgc:110319, Drer\nfu1" Scer\NFU1 Cele\lpd-8 Xtro\nfu1 Mmus\Nfu1 Hsap\NFU1 FBgn0011606 Klp3A Kinesin-like protein at 3A http://flybase.org/reports/FBgn0011606 "FBgn0000827, FBgn0002711, FBgn0010237, FBgn0040374" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from biological aspect of ancestor with PANTHER:PTN001537455 microtubule binding ; GO:0008017 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | non-traceable author statement" meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity single fertilization ; GO:0007338 | inferred from mutant phenotype spindle elongation ; GO:0051231 | inferred from mutant phenotype male meiosis ; GO:0007140 | traceable author statement male meiosis ; GO:0007140 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from sequence or structural similarity midbody ; GO:0030496 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule associated complex ; GO:0005875 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay aster ; GO:0005818 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay "mei-352, KLP3A, klp3A, Klp3a, EG:BACR25B3.9, CG8590, DmKlp3A, KLP-3A, DmKLP3A, fs(1)M4, 3A7Kin, BcDNA:LD21815, Klp3A, KIF4, klp3a, Klp 3A, KIF 4A, KIF4A" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033467:Tesmin/TSO1-like CXC domain" CG8590 11-Aug-17 DroID_v2017_08 "Drer\LOC100537698, Drer\LOC100149074, Drer\kif7, Drer\kif21a, Drer\si:ch73-375g18.1, Drer\kif4, Drer\kif21b" Scer\KIP3 Cele\klp-19 "Xtro\LOC100494653, Xtro\kif21b, Xtro\kif4a, Xtro\kif21a, Xtro\kif27, Xtro\kif7" "Mmus\Kif4, Mmus\Kif7, Mmus\Kif21a, Mmus\Kif27, Mmus\Kif21b" "Hsap\KIF21B, Hsap\KIF27, Hsap\KIF7, Hsap\KIF4B, Hsap\KIF21A, Hsap\KIF4A" embryonic stage -- adult stage " oogenesis stage , embryonic stage " "male sterile,partially,lethal - all die before end of embryonic stage,maternal effect,lethal,some die during embryonic stage,wild-type,female sterile,meiotic cell cycle defective,recessive,female semi-sterile,mitotic cell cycle defective,viable" "spindle microtubule,astral microtubule,mitosis & nuclear chromosome,spindle pole,contractile ring & meiotic cell cycle | male,spindle & meiotic cell cycle | male,spermatocyte ring canal,spermatid,meiotic cell cycle,Nebenkern,condensed nuclear chromosome | embryonic stage,spindle pole | embryonic stage,nucleus & telophase & embryo,spindle | embryonic stage" FBgn0023169 AMPKalpha AMP-activated protein kinase alpha subunit http://flybase.org/reports/FBgn0023169 "FBgn0004836, FBgn0029574" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 AMP-activated protein kinase activity ; GO:0004679 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement G-protein coupled receptor kinase activity ; GO:0004703 | inferred from sequence or structural similarity histone serine kinase activity ; GO:0035174 | inferred from biological aspect of ancestor with PANTHER:PTN000757363 AMP-activated protein kinase activity ; GO:0004679 | inferred from mutant phenotype" protein phosphorylation ; GO:0006468 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of digestive system process ; GO:0044058 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of cell growth ; GO:0001558 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from genetic interaction with Rheb cellular response to starvation ; GO:0009267 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from sequence or structural similarity sequestering of triglyceride ; GO:0030730 | inferred from mutant phenotype behavioral response to starvation ; GO:0042595 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with Rheb lipid metabolic process ; GO:0006629 | inferred from mutant phenotype cellular response to glucose starvation ; GO:0042149 | inferred from biological aspect of ancestor with PANTHER:PTN001217363 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleotide-activated protein kinase complex ; GO:0031588 | inferred from biological aspect of ancestor with PANTHER:PTN001217363 cytoplasm ; GO:0005737 | inferred from direct assay nucleotide-activated protein kinase complex ; GO:0031588 | inferred by curator from GO:0004679 "ampk, AMPK, snf1a, DmAMPK alpha, FBgn0023169, EG:132E8.2, CG3051, Gprk-4, Gprk4, dAMPKa, AMPKalpha, AmpKalpha, dAMPKalpha, SNF1A, ampkalpha, snf1A, dAMPK, AK, AMPK-alpha, SNF4A-a" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR028375:KA1 domain/Ssp2, C-terminal, IPR032270:AMPK, C-terminal adenylate sensor domain" CG3051 11-Aug-17 DroID_v2017_08 "Drer\mark3a, Drer\prkaa2, Drer\brsk2a, Drer\mark4a, Drer\mark2b, Drer\sik1, Drer\sik2b, Drer\mark2a, Drer\prkaa1, Drer\brsk2b, Drer\mark1, Drer\si:ch211-255p10.4, Drer\si:dkey-31m14.7, Drer\mark3b, Drer\si:dkey-16p21.7, Drer\sik2a" "Scer\GIN4, Scer\HSL1, Scer\PRR1, Scer\KIN2, Scer\PTK2, Scer\KIN1, Scer\PTK1, Scer\KCC4, Scer\SNF1" "Cele\aak-2, Cele\aak-1, Cele\sad-1" "Xtro\sik3, Xtro\mark2, Xtro\sik2, Xtro\mark4, Xtro\prkaa2, Xtro\prkaa1, Xtro\mark3" "Mmus\Smok3c, Mmus\Mark4, Mmus\Gm6729, Mmus\Gm5174, Mmus\Brsk1, Mmus\Prkaa2, Mmus\Smok3b, Mmus\Smok3a, Mmus\Gm4922, Mmus\Gm7168, Mmus\Brsk2, Mmus\Sik3, Mmus\Gm6176, Mmus\Gm14147, Mmus\Mark3, Mmus\Gm14151, Mmus\Mark1, Mmus\Smok2a, Mmus\Gm10668, Mmus\Gm7356, Mmus\Sik2, Mmus\Sik1, Mmus\Gm6882, Mmus\Mark2, Mmus\Prkaa1, Mmus\4921509C19Rik, Mmus\1810024B03Rik, Mmus\Gm6902, Mmus\Smok2b" "Hsap\BRSK2, Hsap\PRKAA1, Hsap\CHEK1, Hsap\MARK3, Hsap\SIK1, Hsap\PRKAA2, Hsap\MARK1, Hsap\MARK4, Hsap\BRSK1, Hsap\MARK2, Hsap\SIK2, Hsap\SIK3" "long lived,RU486 conditional,viable,lethal,small body,developmental rate defective,stress response defective,dominant,lethal - all die before end of larval stage,some die during third instar larval stage,short lived,starvation stress response defective,neuroanatomy defective,some die during second instar larval stage,immune response defective,some die during larval stage,increased cell size,somatic clone,locomotor rhythm defective,nutrition conditional,hyperactive,feeding behavior defective,maternal effect,mitotic cell cycle defective,lethal - all die before end of second instar larval stage,recessive,cell polarity defective,cell cycle defective,cytokinesis defective" "hindgut muscle,midgut muscle,longitudinal visceral muscle fiber,circular visceral muscle fiber,hindgut visceral muscle fiber,embryonic/larval digestive system,embryonic/larval fat body,embryonic/larval midgut,dendritic arborizing neuron,plasma membrane | second instar larval stage,dendrite | second instar larval stage,sensory neuron,class IV dendritic arborizing neuron,oenocyte,follicle cell,embryonic/first instar larval cuticle,maternal effect,denticle belt,embryonic epidermis,neuroblast,spindle,centrosome" FBgn0053873 His4:CG33873 His4:CG33873 http://flybase.org/reports/FBgn0053873 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33873, His4:CG33873" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33873 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.12, Drer\LOC100150038, Drer\si:ch73-368j24.1, Drer\si:ch211-113a14.6, Drer\LOC570405, Drer\si:dkey-108k21.19, Drer\si:dkey-261m9.17, Drer\hist1h4l, Drer\si:ch73-36p18.4, Drer\si:ch73-368j24.14, Drer\si:ch73-36p18.3, Drer\si:ch211-113a14.17, Drer\LOC562770, Drer\LOC100331412, Drer\si:ch211-113a14.26, Drer\LOC794549, Drer\LOC100329358, Drer\zgc:163040, Drer\si:dkey-261m9.18, Drer\zgc:154164, Drer\si:dkey-23a13.7, Drer\zgc:194989, Drer\si:dkey-108k21.28, Drer\zgc:153409" "Scer\HHF2, Scer\HHF1" "Cele\his-38, Cele\his-26, Cele\his-56, Cele\his-18, Cele\his-50, Cele\his-37, Cele\his-1, Cele\his-28, Cele\his-60, Cele\his-46, Cele\his-5, Cele\his-67, Cele\his-14, Cele\his-10, Cele\his-64, Cele\his-31" "Xtro\LOC100493041, Xtro\hist1h4k, Xtro\hist1h4c, Xtro\LOC100495184" "Mmus\Hist1h4j, Mmus\Hist1h4a, Mmus\Hist1h4h, Mmus\Hist1h4f, Mmus\Hist1h4n, Mmus\Hist1h4c, Mmus\Hist2h4, Mmus\Hist1h4k, Mmus\Hist4h4, Mmus\Hist1h4m, Mmus\Hist1h4d, Mmus\Hist1h4b, Mmus\Hist1h4i" "Hsap\HIST2H4B, Hsap\HIST1H4A, Hsap\HIST1H4E, Hsap\HIST1H4J, Hsap\HIST2H4A, Hsap\HIST1H4C, Hsap\HIST1H4G, Hsap\HIST1H4I, Hsap\HIST1H4F, Hsap\HIST1H4B, Hsap\HIST4H4, Hsap\HIST1H4K, Hsap\HIST1H4H, Hsap\HIST1H4L, Hsap\HIST1H4D" FBgn0038975 Nrx-1 Neurexin 1 http://flybase.org/reports/FBgn0038975 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from physical interaction with UniProtKB:Q24210 protein binding ; GO:0005515 | inferred from physical interaction with CASK apolipoprotein binding ; GO:0034185 | inferred from physical interaction with apolpp neuroligin family protein binding ; GO:0097109 | inferred from physical interaction with Nlg2 positive regulation of synaptic vesicle endocytosis ; GO:1900244 | inferred from mutant phenotype inferred from genetic interaction with CASK chemical synaptic transmission ; GO:0007268 | inferred from direct assay regulation of locomotion ; GO:0040012 | inferred from mutant phenotype inferred from genetic interaction with CASK regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from mutant phenotype inferred from genetic interaction with CASK vitamin A transport ; GO:0071938 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from direct assay synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype presynaptic membrane assembly ; GO:0097105 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from direct assay terminal button organization ; GO:0072553 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from direct assay integral component of presynaptic membrane ; GO:0099056 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay type I terminal bouton ; GO:0061174 | inferred from mutant phenotype inferred from direct assay trans-synaptic protein complex ; GO:0098820 | inferred from physical interaction with Nlg1 plasma membrane ; GO:0005886 | inferred from direct assay "Nrx, Nrx1, CG7050, dnrx-1, CT21808, Nrx-1, dnrx, nrx, dnrx1, DNrx, nrx-1" "IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR016186:C-type lectin-like/link domain" CG7050 11-Aug-17 DroID_v2017_08 "Drer\nrxn2b, Drer\nrxn3b, Drer\nrxn2a, Drer\nrxn1b, Drer\nrxn3a, Drer\nrxn1a" - Cele\nrx-1 "Xtro\nrxn2, Xtro\nrxn1, Xtro\nrxn3" "Mmus\Nrxn3, Mmus\Nrxn2, Mmus\Nrxn1" "Hsap\NRXN2, Hsap\NRXN3, Hsap\NRXN1" "viable,fertile,short lived,locomotor behavior defective,neurophysiology defective,learning defective,phototaxis defective,neuroanatomy defective,uncoordinated,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuromuscular junction,bouton,synaptic vesicle,synapse,synapseExel6191),neuromuscular junction5C1),type I bouton,NMJ bouton,presynaptic active zone | supernumerary,subsynaptic reticulum,postsynaptic density,neuromuscular junction | larval stageExel6191),neuromuscular junction | embryonic stageExel6191),neuromuscular junction | embryonic stageelav.PLu" FBgn0036072 CG6628 - http://flybase.org/reports/FBgn0036072 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model CG6628 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG6628 11-Aug-17 DroID_v2017_08 "Drer\crispld2, Drer\crispld1a, Drer\glipr2l, Drer\pi15b, Drer\LOC101883528, Drer\glipr2, Drer\r3hdml, Drer\crispld1b, Drer\pi15a, Drer\LOC100536500, Drer\glipr1b" "Scer\PRY1, Scer\PRY3, Scer\PRY2" "Cele\scl-14, Cele\scl-23, Cele\scl-17, Cele\scl-3, Cele\scl-7, Cele\scl-11, Cele\scl-10, Cele\scl-6, Cele\scl-12, Cele\scl-8, Cele\scl-18, Cele\scl-1, Cele\scl-19, Cele\scl-13, Cele\scl-9, Cele\scl-20, Cele\scl-21, Cele\scl-15, Cele\vap-2, Cele\scl-5, Cele\scl-2" "Xtro\glipr2, Xtro\pi15, Xtro\crisp2, Xtro\crispld2, Xtro\r3hdml, Xtro\crisp3, Xtro\crisp1, Xtro\MGC108118" "Mmus\Pi16, Mmus\Clec18a, Mmus\Crisp1, Mmus\Glipr2, Mmus\Crisp3, Mmus\Glipr1l1, Mmus\Pi15, Mmus\Crisp4, Mmus\Crispld1, Mmus\Crisp2, Mmus\Glipr1l2, Mmus\Crispld2, Mmus\R3hdml, Mmus\Glipr1" "Hsap\GLIPR1, Hsap\CRISP2, Hsap\GLIPR2, Hsap\CLEC18C, Hsap\PI15, Hsap\CLEC18B, Hsap\PI16, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\CLEC18A, Hsap\CRISPLD1, Hsap\R3HDML, Hsap\CRISPLD2" viable FBgn0043364 cbt cabut http://flybase.org/reports/FBgn0043364 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with HGNC:11811" "autophagic cell death ; GO:0048102 | inferred from expression pattern positive regulation of decapentaplegic signaling pathway ; GO:0090098 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap sensory organ development ; GO:0007423 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "cbt, CG4427, EP2237, EP(2)2237, dTIEG, Cabot, cabut, Cabut" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4427 11-Aug-17 DroID_v2017_08 "Drer\klf5a, Drer\klf12b, Drer\klf11b, Drer\vezf1b, Drer\sp2, Drer\osr2, Drer\klf2b, Drer\znf740a, Drer\znf362b, Drer\klf12a, Drer\klf2a, Drer\klf13, Drer\egr1, Drer\znf281b, Drer\klf6b, Drer\znf281a, Drer\si:ch211-117k10.3, Drer\klf15, Drer\si:ch211-166g5.4, Drer\klf9, Drer\klf17, Drer\znf740b, Drer\zgc:153115, Drer\egr4, Drer\klf5l, Drer\egr2b, Drer\klf5b, Drer\LOC100535691, Drer\klf7a, Drer\klf6a, Drer\osr1, Drer\vezf1a, Drer\klf8, Drer\klf11a, Drer\klf1, Drer\klf7b, Drer\klf3, Drer\klf4" "Scer\SWI5, Scer\MSN4, Scer\MSN2, Scer\CRZ1, Scer\RPN4, Scer\FZF1, Scer\ACE2, Scer\AZF1" "Cele\odd-2, Cele\egrh-3, Cele\egrh-1, Cele\klu-1, Cele\sptf-2, Cele\klf-3, Cele\klf-2, Cele\odd-1" "Xtro\klf9, Xtro\klf7, Xtro\klf2, Xtro\klf10, Xtro\klf12, Xtro\egr3, Xtro\klf17, Xtro\sp2, Xtro\osr1, Xtro\klf11, Xtro\klf4, Xtro\klf8, Xtro\klf13, Xtro\znf534, Xtro\klf3, Xtro\egr2, Xtro\osr2, Xtro\klf15, Xtro\klf5, Xtro\egr1" "Mmus\Zfp362, Mmus\Vezf1, Mmus\Egr4, Mmus\Klf16, Mmus\Klf3, Mmus\Osr2, Mmus\Klf14, Mmus\Klf15, Mmus\Klf10, Mmus\Klf6, Mmus\Klf5, Mmus\Egr1, Mmus\Klf11, Mmus\Klf9, Mmus\Klf2, Mmus\Klf13, Mmus\Maz, Mmus\Egr3, Mmus\Klf1, Mmus\Klf7, Mmus\Osr1, Mmus\Zfp281, Mmus\Klf12, Mmus\Klf4, Mmus\Klf8, Mmus\Zfp174, Mmus\Sp2" "Hsap\ZNF740, Hsap\KLF16, Hsap\EGR3, Hsap\KLF8, Hsap\KLF5, Hsap\KLF15, Hsap\EGR4, Hsap\KLF6, Hsap\ZNF362, Hsap\EGR1, Hsap\KLF4, Hsap\KLF1, Hsap\KLF3, Hsap\KLF12, Hsap\KLF9, Hsap\VEZF1, Hsap\KLF10, Hsap\KLF2, Hsap\KLF14, Hsap\ZNF281, Hsap\KLF13, Hsap\SP2, Hsap\ZNF174, Hsap\OSR2, Hsap\KLF11, Hsap\EGR2, Hsap\ZSCAN16, Hsap\MAZ, Hsap\KLF7, Hsap\OSR1" "visible,increased cell number,partially lethal,conditional,developmental rate defective,neuroanatomy defective,viable,recessive,lethal - all die before end of embryonic stage,partially,some die during embryonic stage,cell polarity defective" "crossvein,1st posterior cell,wing,wing vein L5,wing margin,wing vein,wing pouch,wing disc,posterior compartment,dorsocentral bristle,scutellar bristle,ectopic,trichogen cell,tormogen cell,ocellus,anterior fascicle & synapse,neurite | pharate adult stage,embryonic/first instar larval cuticle,anterior,dorsal closure embryo,dorsal,embryonic leading edge cell,leading edge & filamentous actin,leading edge & muscle myosin complex,amnioserosa" FBgn0030521 CtsB1 Cathepsin B1 http://flybase.org/reports/FBgn0030521 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay peptidase activity ; GO:0008233 | inferred from direct assay regulation of catalytic activity ; GO:0050790 | inferred from electronic annotation with InterPro:IPR012599 proteolysis ; GO:0006508 | inferred from direct assay proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern perivitelline space ; GO:0098595 | inferred from direct assay lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000274640 "anon-EST:ParkEST132, CG10992, CG-10992, CtsB1, CTSB1, CB" "IPR025661:Cysteine peptidase, asparagine active site, IPR025660:Cysteine peptidase, histidine active site, IPR000169:Cysteine peptidase, cysteine active site, IPR000668:Peptidase C1A, papain C-terminal, IPR012599:Peptidase C1A, propeptide, IPR013128:Peptidase C1A" CG10992 11-Aug-17 DroID_v2017_08 "Drer\LOC100333521, Drer\si:dkey-239j18.3, Drer\si:dkey-269i1.4, Drer\ctsba, Drer\ctss1, Drer\si:dkey-228a15.1, Drer\ctsl.1, Drer\ctsc, Drer\ctsbb, Drer\ctsla, Drer\wu:fa26c03, Drer\cts12, Drer\ctss2.2, Drer\ctss2.1, Drer\ctsll, Drer\si:dkey-239j18.2, Drer\ctsk, Drer\zgc:174855, Drer\ctsz, Drer\MGC174155, Drer\ctsh, Drer\zgc:103438, Drer\LOC100536033, Drer\zgc:174153, Drer\si:dkey-267n13.1, Drer\si:dkey-183k8.2, Drer\ctslb, Drer\zgc:110239" - "Cele\cpr-2, Cele\cpr-6, Cele\cpr-4, Cele\F32H5.1, Cele\F57F5.1, Cele\cpr-8, Cele\cpr-3, Cele\cpr-1, Cele\Y65B4A.2, Cele\cpr-5, Cele\W07B8.4" "Xtro\ctsc, Xtro\ctss, Xtro\LOC100498238, Xtro\ctsl, Xtro\ctsv, Xtro\ctsz, Xtro\ctsb, Xtro\LOC100490139, Xtro\ctsh" "Mmus\Ctsc, Mmus\Ctsb, Mmus\Cts3, Mmus\4930486L24Rik, Mmus\Ctla2a, Mmus\Cts7, Mmus\BC051665, Mmus\Ctsh, Mmus\Ctsj, Mmus\Ctsz, Mmus\Ctsr, Mmus\Cts8, Mmus\Ctla2b, Mmus\Ctss, Mmus\Ctsl, Mmus\Ctsq, Mmus\Cts6, Mmus\Ctsk, Mmus\Ctsll3, Mmus\Ctsm" "Hsap\CTSS, Hsap\CTSB, Hsap\CTSH, Hsap\CTSK, Hsap\CTSL, Hsap\CTSC, Hsap\CTSV, Hsap\CTSZ" "viable,lethal,recessive" FBgn0033983 ADPS Alkyldihydroxyacetonephosphate synthase http://flybase.org/reports/FBgn0033983 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR016166 alkylglycerone-phosphate synthase activity ; GO:0008609 | inferred from sequence or structural similarity with HGNC:327 alkylglycerone-phosphate synthase activity ; GO:0008609 | inferred from sequence or structural similarity with UniProtKB:P97275 FAD binding ; GO:0071949 | inferred from sequence or structural similarity with UniProtKB:P97275" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006094, InterPro:IPR016166, InterPro:IPR016167 ether lipid biosynthetic process ; GO:0008611 | inferred from sequence or structural similarity with UniProtKB:P97275 lipid biosynthetic process ; GO:0008610 | inferred from sequence or structural similarity with HGNC:327" peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:327 inferred from sequence model inferred from direct assay "CG10253, dAGPS, ADPS" "IPR004113:FAD-linked oxidase, C-terminal, IPR006094:FAD linked oxidase, N-terminal, IPR025650:Alkyldihydroxyacetonephosphate synthase, IPR016164:FAD-linked oxidase-like, C-terminal, IPR016166:FAD-binding, type 2, IPR016167:FAD-binding, type 2, subdomain 1, IPR016171:Vanillyl-alcohol oxidase, C-terminal subdomain 2, IPR016169:CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2" CG10253 11-Aug-17 DroID_v2017_08 Drer\agps Scer\DLD1 Cele\ads-1 Xtro\agps Mmus\Agps Hsap\AGPS viable FBgn0033339 Sec31 Secretory 31 http://flybase.org/reports/FBgn0033339 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity with SGD:S000002354 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype COPII-coated vesicle budding ; GO:0090114 | inferred from sequence or structural similarity with SGD:S000002354 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype endoplasmic reticulum exit site ; GO:0070971 | inferred from direct assay COPII vesicle coat ; GO:0030127 | inferred from sequence or structural similarity with SGD:S000002354 Golgi stack ; GO:0005795 | inferred from direct assay ER to Golgi transport vesicle ; GO:0030134 | traceable author statement endoplasmic reticulum ; GO:0005783 | inferred from direct assay endoplasmic reticulum exit site ; GO:0070971 | "dSec31p, CG8266, Sec31, SEC31, sec31" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR011990:Tetratricopeptide-like helical domain, IPR024298:Ancestral coatomer element 1, Sec16/Sec31" CG8266 11-Aug-17 DroID_v2017_08 "Drer\sec31b, Drer\sec31a" Scer\SEC31 Cele\sec-31 "Xtro\sec31a, Xtro\sec31b" "Mmus\Sec31b, Mmus\Sec31a" "Hsap\SEC31A, Hsap\SEC31B" "viable,visible,short lived,gravitaxis defective" trichogen cell DRSC27091 K -0.089724587 0.189959839 -0.760778086 0.584959179 2.669818277 0.106700452 FBgn0010412 RpS19a Ribosomal protein S19a http://flybase.org/reports/FBgn0010412 FBgn0063184 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001266, InterPro:IPR018277 cytoplasmic translation ; GO:0002181 | traceable author statement ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000194951 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CG4464, RpS19, S19, BcDNA:GM26647, RpS19a, S19a, Rp S19a" "IPR018277:Ribosomal protein S19e, conserved site, IPR001266:Ribosomal protein S19e, IPR011991:Winged helix-turn-helix DNA-binding domain" CG4464 11-Aug-17 DroID_v2017_08 Drer\rps19 "Scer\RPS19B, Scer\RPS19A" Cele\rps-19 Xtro\rps19 Mmus\Rps19 Hsap\RPS19 FBgn0033095 CG3409 - http://flybase.org/reports/FBgn0033095 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG3409 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG3409 11-Aug-17 DroID_v2017_08 "Drer\slc16a9a, Drer\slc16a6a, Drer\si:dkey-246g23.4, Drer\zgc:114041, Drer\slc16a13, Drer\slc16a6b, Drer\LOC103911912, Drer\slc16a4, Drer\slc16a12b, Drer\slc16a9b, Drer\slc16a12a" "Scer\MCH5, Scer\ATG22, Scer\ESBP6, Scer\MCH2, Scer\MCH4" "Cele\mct-4, Cele\gem-1, Cele\mct-5, Cele\mct-3, Cele\mct-6" "Xtro\slc16a9, Xtro\slc16a12" "Mmus\Slc16a14, Mmus\Slc16a9, Mmus\Slc16a13, Mmus\Slc16a12, Mmus\Slc16a6, Mmus\Slc16a4, Mmus\Slc16a11" "Hsap\SLC16A12, Hsap\SLC16A6, Hsap\SLC16A9, Hsap\SLC16A11, Hsap\SLC16A13, Hsap\SLC16A4, Hsap\SLC16A14" "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0086130 Dbp21E2 DEAD box protein 21E2 http://flybase.org/reports/FBgn0086130 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000618871 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 cytoplasm ; GO:0005737 | inferred from direct assay "CG3561, DmRH9, cg3561, Dbp21E2, KH1" "IPR014014:RNA helicase, DEAD-box type, Q motif, IPR011545:DEAD/DEAH box helicase domain, IPR001650:Helicase, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3561 11-Aug-17 DroID_v2017_08 "Drer\ddx28, Drer\tdrd12, Drer\ddx49" "Scer\MRH4, Scer\DRS1, Scer\PRP5, Scer\RRP3" "Cele\T26G10.1, Cele\Y54G11A.3, Cele\C24H12.4, Cele\rde-12" "Xtro\ddx47, Xtro\ddx28, Xtro\ddx49" "Mmus\Ddx47, Mmus\Ddx49, Mmus\Ddx28" "Hsap\DDX28, Hsap\DDX47, Hsap\DDX49" FBgn0036816 Indy I'm not dead yet http://flybase.org/reports/FBgn0036816 protein_coding_gene pyruvate transmembrane transporter activity ; GO:0050833 | inferred from direct assay succinate transmembrane transporter activity ; GO:0015141 | inferred from direct assay citrate transmembrane transporter activity ; GO:0015137 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001898 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR001898 succinate transport ; GO:0015744 | inferred from direct assay citrate transport ; GO:0015746 | inferred from direct assay determination of adult lifespan ; GO:0008340 | traceable author statement determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | NOT inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from direct assay regulation of sequestering of triglyceride ; GO:0010889 | inferred from direct assay pyruvate transport ; GO:0006848 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000815082 plasma membrane ; GO:0005886 | inferred from direct assay "indy, drIndy, BEST:LP01220, anon-EST:fe3A7, CG3979, anon-WO0172774.70, Indy, INDY" "IPR001898:Solute carrier family 13, IPR031312:Sodium/sulphate symporter, conserved site" CG3979 11-Aug-17 DroID_v2017_08 "Drer\slc13a5a, Drer\slc13a3, Drer\slc13a1, Drer\slc13a2, Drer\slc13a4, Drer\slc13a5b" "Scer\PHO90, Scer\PHO87, Scer\PHO91" "Cele\nac-2, Cele\nac-3, Cele\B0285.6, Cele\nac-1" "Xtro\slc13a5, Xtro\slc13a2, Xtro\slc13a1, Xtro\slc13a4, Xtro\slc13a3" "Mmus\Slc13a4, Mmus\Slc13a5, Mmus\Slc13a1, Mmus\Slc13a3, Mmus\Slc13a2" "Hsap\SLC13A4, Hsap\SLC13A5, Hsap\SLC13A2, Hsap\SLC13A3, Hsap\SLC13A1" "lethal,recessive,viable,fertile,long lived,dominant,male fertile,female fertile,reduced,poor,lethal - all die before end of embryonic stage,partially,some die during embryonic stage" FBgn0263605 l(3)72Dn lethal (3) 72Dn http://flybase.org/reports/FBgn0263605 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cellular response to starvation ; GO:0009267 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG5018, l(3)72Dn, l(3)j5A4" "IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR011044:Quinoprotein amine dehydrogenase, beta chain-like, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG5018 11-Aug-17 DroID_v2017_08 "Drer\cirh1a, Drer\wdr95" "Scer\PAC1, Scer\MET30, Scer\UTP4, Scer\RPN14" Cele\K05C4.5 Xtro\utp4 "Mmus\Wdr95, Mmus\Cirh1a" Hsap\UTP4 FBgn0051345 CG31345 - http://flybase.org/reports/FBgn0051345 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000095441 phagocytosis ; GO:0006909 | inferred from mutant phenotype - "CG10135, CG14388, CG31345, CBP9" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG31345 11-Aug-17 DroID_v2017_08 "Drer\camk1a, Drer\camk1b, Drer\camk1ga, Drer\dapk2b, Drer\camkvl, Drer\pnck, Drer\pskh1, Drer\mylk4a, Drer\si:dkey-240h12.4, Drer\triob, Drer\camkva, Drer\caps2, Drer\dapk3, Drer\camk4, Drer\stk17b, Drer\si:ch73-60h1.1, Drer\camk1da, Drer\ttnb, Drer\spegb, Drer\si:ch211-27e6.1, Drer\stk17a, Drer\camkvb, Drer\stk33, Drer\mylk4b, Drer\capslb, Drer\trioa, Drer\mylk3, Drer\zgc:153952, Drer\camk1gb, Drer\dapk1, Drer\dapk2a, Drer\uhmk1, Drer\camk1db, Drer\capsla" "Scer\RCK2, Scer\IKS1, Scer\RCK1, Scer\CMK2, Scer\TDA1, Scer\CMK1, Scer\MEK1" "Cele\cal-8, Cele\F43C9.2" "Xtro\camk4, Xtro\camk1, Xtro\camk1g, Xtro\caps, Xtro\stk17a, Xtro\camkv, Xtro\capsl, Xtro\pskh1, Xtro\dclk2, Xtro\dapk1, Xtro\dapk3, Xtro\kalrn, Xtro\pskh2, Xtro\stk33, Xtro\dapk2, Xtro\camk1d, Xtro\mylk4, Xtro\mylk3, Xtro\pnck, Xtro\trio" "Mmus\Camk1, Mmus\Uhmk1, Mmus\Trio, Mmus\Camkv, Mmus\Obscn, Mmus\Dapk3, Mmus\Mylk3, Mmus\Dclk1, Mmus\Pnck, Mmus\Mylk4, Mmus\Mylk2, Mmus\Dclk2, Mmus\Camk1g, Mmus\Capsl, Mmus\Camk1d, Mmus\Pskh1, Mmus\Dapk2, Mmus\Stk33, Mmus\Dapk1, Mmus\Caps2, Mmus\Stk17b, Mmus\Camk4, Mmus\Speg" "Hsap\PNCK, Hsap\STK17B, Hsap\STK33, Hsap\PSKH2, Hsap\DCLK1, Hsap\STK17A, Hsap\DAPK3, Hsap\UHMK1, Hsap\CAMKV, Hsap\OBSCN, Hsap\CAMK1, Hsap\DAPK2, Hsap\MYLK2, Hsap\SPEG, Hsap\CAMK1D, Hsap\CAPS2, Hsap\PSKH1, Hsap\TRIO, Hsap\CAPS, Hsap\CAPSL, Hsap\MYLK3, Hsap\DAPK1, Hsap\CAMK4, Hsap\MYLK4, Hsap\CAMK1G" viable FBgn0031986 CG8673 - http://flybase.org/reports/FBgn0031986 protein_coding_gene galactosyltransferase activity ; GO:0008378 | inferred from electronic annotation with InterPro:IPR002659 protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR002659 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "CG8673, dbeta3GnT, GalT5" "IPR002659:Glycosyl transferase, family 31" CG8673 11-Aug-17 DroID_v2017_08 "Drer\b3gnt2b, Drer\si:ch211-126g16.11, Drer\b3galt4, Drer\b3galt1b, Drer\b3gnt2a, Drer\b3gnt7l, Drer\si:dkey-175m17.6, Drer\b3galt1a, Drer\b3gnt2l, Drer\si:dkey-160o24.3, Drer\LOC565422, Drer\b3gnt9, Drer\b3gnt5a, Drer\si:ch73-195i19.3, Drer\zgc:194330, Drer\zgc:194551, Drer\b3galt2, Drer\b3gnt5b, Drer\LOC100535930, Drer\b3galnt2, Drer\LOC100333524, Drer\b3gnt3, Drer\b3gnt7, Drer\zgc:86586" - "Cele\F14B6.6, Cele\F48F7.3, Cele\bre-5, Cele\C47F8.5, Cele\F14B6.4, Cele\T09E11.10, Cele\B0024.15, Cele\E03H4.11, Cele\T09F5.1, Cele\T15D6.5, Cele\bus-2, Cele\C47F8.3, Cele\bre-2" "Xtro\b3gnt5, Xtro\b3gnt4, Xtro\b3gnt6, Xtro\b3galt4, Xtro\b3galt2, Xtro\b3gnt3, Xtro\LOC100494507, Xtro\b3galnt2, Xtro\LOC100489267, Xtro\LOC100494668, Xtro\b3gnt3, Xtro\b3galt5, Xtro\LOC100493833, Xtro\LOC100494986, Xtro\b3galt1, Xtro\LOC100487553, Xtro\LOC100493669, Xtro\b3gnt2" "Mmus\B3galnt1, Mmus\B3gnt8, Mmus\B3gnt2, Mmus\B3gnt5, Mmus\B3galt5, Mmus\B3gnt3, Mmus\B3galnt2, Mmus\B3gnt9, Mmus\B3galt1, Mmus\B3gnt7, Mmus\B3galt2, Mmus\B3galt4, Mmus\B3gnt4, Mmus\B3gnt6" "Hsap\B3GALNT2, Hsap\B3GNT2, Hsap\B3GNT4, Hsap\B3GNT8, Hsap\B3GALT2, Hsap\B3GNT9, Hsap\B3GNT5, Hsap\B3GALT4, Hsap\B3GALNT1, Hsap\B3GNT3, Hsap\B3GNT6, Hsap\B3GALT5, Hsap\B3GALT1, Hsap\B3GNT7" "partially lethal - majority die,visible" mesothoracic tergum FBgn0031003 CG7889 - http://flybase.org/reports/FBgn0031003 protein_coding_gene protein-lysine N-methyltransferase activity ; GO:0016279 | inferred from sequence or structural similarity with SGD:S000003890 peptidyl-lysine trimethylation ; GO:0018023 | inferred from sequence or structural similarity with SGD:S000003890 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003890 CG7889 "IPR019410:Lysine methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR029426:FAM86" CG7889 11-Aug-17 DroID_v2017_08 "Drer\zgc:172067, Drer\mettl20, Drer\LOC100149425, Drer\mettl21a, Drer\eef2kmt, Drer\zgc:92518, Drer\mettl22" "Scer\EFM6, Scer\NNT1, Scer\EFM2, Scer\EFM3" "Cele\R08D7.4, Cele\C42C1.13, Cele\Y48E1C.1" "Xtro\mettl21b, Xtro\mettl21a, Xtro\eef2kmt, Xtro\mettl23" "Mmus\Vcpkmt, Mmus\Mettl23, Mmus\Mettl21a, Mmus\Mettl21b, Mmus\Mettl21e, Mmus\Mettl22, Mmus\Mettl21c, Mmus\Etfbkmt, Mmus\Eef2kmt" "Hsap\FAM86B2, Hsap\FAM86B1, Hsap\VCPKMT, Hsap\METTL21B, Hsap\METTL22, Hsap\EEF2KMT, Hsap\METTL23, Hsap\METTL21C, Hsap\METTL21A, Hsap\FAM86C1" DRSC26654 K -0.377025542 -0.045296359 -0.420786741 -0.059214849 0.999802219 -1.553344791 FBgn0029648 CG3603 - http://flybase.org/reports/FBgn0029648 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "BcDNA:RH09070, CG3603" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG3603 11-Aug-17 DroID_v2017_08 "Drer\elovl7a, Drer\decr2, Drer\elovl7b, Drer\elovl5, Drer\zgc:101858, Drer\bdh2, Drer\elovl4b, Drer\elovl2, Drer\elovl8a, Drer\elovl8b, Drer\hsd17b8, Drer\dhrs7, Drer\elovl1a, Drer\elovl1b, Drer\cbr4, Drer\zgc:113054, Drer\hsd17b14, Drer\elovl4a" "Scer\SPS19, Scer\YIR035C, Scer\OAR1" "Cele\dhs-14, Cele\dhs-25, Cele\F25D1.5, Cele\Y47G6A.22, Cele\F12E12.11, Cele\Y47G6A.21, Cele\dhs-11, Cele\decr-1.2, Cele\F28H7.2, Cele\C06E4.3, Cele\F26D2.15, Cele\ZK829.1, Cele\D1054.8" "Xtro\MGC79752, Xtro\dhrs7, Xtro\cbr4, Xtro\elovl5, Xtro\hsd17b8, Xtro\elovl2, Xtro\elovl1, Xtro\elovl7, Xtro\hsd17b14" "Mmus\Decr2, Mmus\Hsd17b14, Mmus\Elovl4, Mmus\Elovl5, Mmus\Dhrs7, Mmus\H2-Ke6, Mmus\Elovl7, Mmus\Cbr4, Mmus\Bdh2, Mmus\Elovl2" "Hsap\ELOVL7, Hsap\ELOVL2, Hsap\HSD17B8, Hsap\ELOVL4, Hsap\HSD17B14, Hsap\BDH2, Hsap\ELOVL1, Hsap\ELOVL5, Hsap\DECR2, Hsap\DHRS7, Hsap\CBR4" FBgn0033451 CG1665 - http://flybase.org/reports/FBgn0033451 protein_coding_gene molybdenum ion binding ; GO:0030151 | inferred from electronic annotation with InterPro:IPR005302 catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR005302 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR005302 - - "CG1665, IP19920p" "IPR005302:Molybdenum cofactor sulfurase, C-terminal, IPR005303:MOSC, N-terminal beta barrel, IPR011037:Pyruvate kinase-like, insert domain" CG1665 11-Aug-17 DroID_v2017_08 Drer\zgc:110783 - "Cele\F22B8.7, Cele\F53E10.1, Cele\F56A11.5" Xtro\marc1 "Mmus\Marc2, Mmus\Marc1" "Hsap\MARC2, Hsap\MARC1" viable FBgn0032688 CG15160 - http://flybase.org/reports/FBgn0032688 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mRNA 3'-end processing ; GO:0031124 | inferred from sequence or structural similarity with SGD:S000002697 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with SGD:S000002697 CG15160 "IPR006569:CID domain, IPR006903:RNA polymerase II-binding domain, IPR008942:ENTH/VHS, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032337:Cell-cycle alteration and expression-elevated protein in tumour" CG15160 11-Aug-17 DroID_v2017_08 "Drer\rprd1b, Drer\rprd2a, Drer\slc30a8, Drer\rprd2b" Scer\RTT103 "Cele\cids-2, Cele\cids-1" "Xtro\rprd1a, Xtro\rprd1b, Xtro\rprd2" "Mmus\Rprd2, Mmus\Rprd1b, Mmus\Rprd1a" "Hsap\RPRD1B, Hsap\RPRD2, Hsap\RPRD1A" viable DRSC02461 IK -2.233957187 -0.09032007 -0.642831396 0.325038361 -0.932926621 -1.922811868 FBgn0030434 Brms1 BRMS1 http://flybase.org/reports/FBgn0030434 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from biological aspect of ancestor with PANTHER:PTN001095090 histone deacetylase activity ; GO:0004407 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001095090 "histone deacetylation ; GO:0016575 | inferred from biological aspect of ancestor with PANTHER:PTN001095090 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN001095090 positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype" Sin3-type complex ; GO:0070822 | inferred from direct assay "CG4400, BRMS1L, Brms1, dBrms1" IPR013907:Sds3-like CG4400 11-Aug-17 DroID_v2017_08 "Drer\brms1, Drer\brms1la, Drer\brms1lb, Drer\suds3" "Scer\DEP1, Scer\SDS3" "Cele\suds-3, Cele\sdz-14" "Xtro\brms1, Xtro\suds3, Xtro\brms1l" "Mmus\Brms1l, Mmus\Brms1, Mmus\Suds3" "Hsap\BRMS1L, Hsap\BRMS1, Hsap\SUDS3" "viable,fertile,lethal - all die before end of prepupal stage,recessive,some die during first instar larval stage,some die during second instar larval stage,majority die during third instar larval stage,some die during prepupal stage,some die during third instar larval stage,developmental rate defective,visible,partially lethal - majority die,some die during pupal stage" "eye-antennal disc,wing disc,trichogen cell" DRSC19896 K -1.39615309 0.951794383 0.338262235 0.74032614 1.88591217 1.993852351 FBgn0051624 CG31624 - http://flybase.org/reports/FBgn0051624 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 - - "CG31624, CG17401, Tes88" "IPR001781:Zinc finger, LIM-type" CG31624 11-Aug-17 DroID_v2017_08 "Drer\pdlim4, Drer\pdlim5b, Drer\zyx, Drer\pxna, Drer\pdlim3b, Drer\si:rp71-15d4.1, Drer\pdlim3a, Drer\pxnb, Drer\pdlim5a, Drer\pdlim1, Drer\fhl3b, Drer\fhl3a, Drer\pdlim2" "Scer\PXL1, Scer\LRG1" "Cele\alp-1, Cele\Y1A5A.1" "Xtro\pdlim1, Xtro\pdlim3, Xtro\pdlim4, Xtro\fhl2, Xtro\pdlim7, Xtro\pdlim5, Xtro\fhl3, Xtro\tgfb1i1, Xtro\fhl5, Xtro\pxn" "Mmus\Pxn, Mmus\Pdlim7, Mmus\Tgfb1i1, Mmus\Pdlim4, Mmus\Fhl3, Mmus\Fhl4, Mmus\Pdlim3, Mmus\Pdlim5, Mmus\Ldb3, Mmus\Pdlim1, Mmus\Fhl1, Mmus\Fhl5, Mmus\Fhl2, Mmus\Lpxn, Mmus\Pdlim2" "Hsap\PDLIM5, Hsap\PDLIM2, Hsap\LDB3, Hsap\FHL1, Hsap\PDLIM4, Hsap\PDLIM1, Hsap\PDLIM7, Hsap\LPXN, Hsap\FHL5, Hsap\PDLIM3, Hsap\FHL2, Hsap\TGFB1I1, Hsap\FHL3, Hsap\PXN" FBgn0026268 antdh antdh http://flybase.org/reports/FBgn0026268 - protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from sequence model oxidation-reduction process ; GO:0055114 | inferred from sequence model sensory perception of smell ; GO:0007608 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from sequence model "AntDH, CG1386, antdh, Antdh, FOHSDR" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG1386 11-Aug-17 DroID_v2017_08 "Drer\dhrs11b, Drer\dhrs11a, Drer\zgc:92630" Scer\YMR226C "Cele\F25D1.5, Cele\H04M03.3" Xtro\dhrs11 "Mmus\Rdh8, Mmus\Dhrs11" "Hsap\DHRS11, Hsap\RDH8" adult stage antennal segment 3

viable FBgn0036770 Prestin Prestin http://flybase.org/reports/FBgn0036770 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 calcium ion transmembrane transporter activity ; GO:0015085 | inferred from direct assay oxalate transmembrane transporter activity ; GO:0019531 | inferred from direct assay bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from direct assay sulfate transmembrane transporter activity ; GO:0015116 | inferred from direct assay formate transmembrane transporter activity ; GO:0015499 | inferred from direct assay inorganic anion exchanger activity ; GO:0005452 | inferred from direct assay anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 oxalate transport ; GO:0019532 | inferred from direct assay chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 formate transport ; GO:0015724 | inferred from direct assay calcium ion transmembrane transport ; GO:0070588 | inferred from direct assay regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transport ; GO:0008272 | inferred from direct assay bicarbonate transport ; GO:0015701 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 "dpres, CG5485, Prestin, Slc26a5, dPrestin, CG5845, prestin" "IPR001902:SLC26A/SulP transporter, IPR002645:STAS domain, IPR011547:SLC26A/SulP transporter domain" CG5485 11-Aug-17 DroID_v2017_08 "Drer\slc26a11, Drer\LOC558704, Drer\slc26a10, Drer\slc26a3.2, Drer\si:ch211-117c9.2, Drer\slc26a5, Drer\slc26a2, Drer\slc26a3.1, Drer\slc26a4, Drer\slc26a6, Drer\slc26a6l, Drer\slc26a1" "Scer\YPR003C, Scer\YGR125W, Scer\SUL1, Scer\SUL2" "Cele\sulp-1, Cele\sulp-4, Cele\sulp-7, Cele\sulp-6, Cele\sulp-3, Cele\sulp-2, Cele\sulp-8, Cele\sulp-5" "Xtro\slc26a10, Xtro\slc26a9, Xtro\slc26a7, Xtro\slc26a1, Xtro\slc26a5, Xtro\slc26a11, Xtro\slc26a6, Xtro\slc26a2, Xtro\slc26a4" "Mmus\Slc26a7, Mmus\Slc26a8, Mmus\Slc26a6, Mmus\Slc26a11, Mmus\Slc26a1, Mmus\Slc26a2, Mmus\Slc26a3, Mmus\Slc26a4, Mmus\Slc26a5, Mmus\Slc26a9, Mmus\Slc26a10" "Hsap\SLC26A8, Hsap\SLC26A4, Hsap\SLC26A9, Hsap\SLC26A11, Hsap\SLC26A5, Hsap\SLC26A3, Hsap\SLC26A1, Hsap\ARHGEF25, Hsap\SLC26A7, Hsap\SLC26A6, Hsap\SLC26A2, Hsap\SLC26A10" viable DRSC10507 EK -0.154824763 0.28172203 0.420070644 1.500822397 1.601242355 1.825557739 FBgn0064123 stg1 stargazin-like protein http://flybase.org/reports/FBgn0064123 protein_coding_gene voltage-gated calcium channel activity ; GO:0005245 | inferred from biological aspect of ancestor with PANTHER:PTN000251098 channel regulator activity ; GO:0016247 | inferred from direct assay "regulation of synaptic transmission, glutamatergic ; GO:0051966 | inferred from direct assay calcium ion transmembrane transport ; GO:0070588 | inferred from biological aspect of ancestor with PANTHER:PTN000251098 transmission of nerve impulse ; GO:0019226 | inferred from biological aspect of ancestor with PANTHER:PTN000251098 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity ; GO:2000311 | inferred from direct assay" integral component of membrane ; GO:0016021 | inferred from sequence model AMPA glutamate receptor complex ; GO:0032281 | inferred from biological aspect of ancestor with PANTHER:PTN000251098 "CG32514, CG11569, CG11568, CG10985, CG32514-ORFA, stg1, STG1, Dro STG1, CG33670, Stg1" IPR004031:PMP-22/EMP/MP20/Claudin superfamily CG33670 11-Aug-17 DroID_v2017_08 "Drer\cacng7a, Drer\cacng5b, Drer\cacng7b, Drer\cacng4a, Drer\cacng8a, Drer\cacng3b, Drer\cacng2a, Drer\cacng4b, Drer\cacng2b, Drer\cacng8b, Drer\cacng5a, Drer\tmem114, Drer\si:ch73-369d14.2, Drer\cacng3a" - "Cele\stg-1, Cele\stg-2" "Xtro\cacng4, Xtro\cacng7, Xtro\tmem114, Xtro\cacng8, Xtro\cacng3" "Mmus\Cacng7, Mmus\Cacng8, Mmus\Cacng3, Mmus\Cacng4, Mmus\Tmem114, Mmus\Cacng5, Mmus\Tmem235, Mmus\Cacng2" "Hsap\CACNG5, Hsap\CACNG7, Hsap\TMEM235, Hsap\CACNG3, Hsap\CACNG8, Hsap\CACNG2, Hsap\CACNG4" "viable,fertile" FBgn0266720 Snap24 Synaptosomal-associated protein 24kDa http://flybase.org/reports/FBgn0266720 protein_coding_gene syntaxin binding ; GO:0019905 | inferred from sequence or structural similarity with RGD:620221 SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000447753 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000447753 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with RGD:620221 membrane fusion ; GO:0061025 | inferred from sequence or structural similarity with RGD:620221 synaptic vesicle priming ; GO:0016082 | inferred from biological aspect of ancestor with PANTHER:PTN000447754 Golgi to plasma membrane transport ; GO:0006893 | inferred from sequence or structural similarity vesicle-mediated transport ; GO:0016192 | non-traceable author statement synaptic vesicle fusion to presynaptic active zone membrane ; GO:0031629 | inferred from biological aspect of ancestor with PANTHER:PTN000447754 neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with RGD:620221 secretory granule membrane ; GO:0030667 | inferred from direct assay SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with RGD:620221 secretory granule ; GO:0030141 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000447753 "Snap24, SNAP-24, SNAP24, CG9474, SNAP-25b, Snap25b" "IPR000727:Target SNARE coiled-coil homology domain, IPR000928:SNAP-25" CG9474 11-Aug-17 DroID_v2017_08 "Drer\snap23.1, Drer\snap25a, Drer\snap29, Drer\zgc:101731, Drer\snap25b, Drer\snap23.2" "Scer\SPO20, Scer\SEC9" "Cele\aex-4, Cele\ric-4" "Xtro\snap23, Xtro\snap25, Xtro\snap47, Xtro\snap29" "Mmus\Snap25, Mmus\Snap47, Mmus\Snap23, Mmus\Snap29" "Hsap\SNAP47, Hsap\SNAP23, Hsap\SNAP25, Hsap\SNAP29" FBgn0036239 Pop2 Pop2 http://flybase.org/reports/FBgn0036239 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 poly(A)-specific ribonuclease activity ; GO:0004535 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR027212 negative regulation of translation ; GO:0017148 | inferred from direct assay neuron development ; GO:0048666 | inferred from mutant phenotype nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from direct assay muscle organ development ; GO:0007517 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs" cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay CCR4-NOT complex ; GO:0030014 | inferred from direct assay "CAF1, CNOT7, CG5684, POP2, Pop2, pop2, Caf1" "IPR006941:Ribonuclease CAF1, IPR012337:Ribonuclease H-like domain, IPR027212:CCR4-NOT transcription complex subunit 8" CG5684 11-Aug-17 DroID_v2017_08 "Drer\cnot7, Drer\cnot8" Scer\POP2 Cele\ccf-1 "Xtro\cnot7, Xtro\cnot8" "Mmus\Cnot7, Mmus\Cnot8" "Hsap\CNOT7, Hsap\CNOT8" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC10537 IEK -0.006786555 -2.665054549 -4.264750873 -4.157301268 1.238205636 1.773006069 FBgn0035519 CG1309 - http://flybase.org/reports/FBgn0035519 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay CG1309 "IPR029058:Alpha/Beta hydrolase fold, IPR000073:Alpha/beta hydrolase fold-1" CG1309 11-Aug-17 DroID_v2017_08 Drer\abhd16a - Cele\F37A4.1 Xtro\abhd16a "Mmus\Abhd16b, Mmus\Abhd16a" "Hsap\ABHD16B, Hsap\ABHD16A" viable FBgn0029831 CG5966 - http://flybase.org/reports/FBgn0029831 protein_coding_gene "carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734, InterPro:IPR016272 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820" imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG5966, 141233_at" "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR016272:Lipase, LIPH-type, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG5966 11-Aug-17 DroID_v2017_08 "Drer\LOC100331214, Drer\lipia, Drer\sco2, Drer\pla1a, Drer\LOC101884800, Drer\lipib, Drer\sco1" - "Cele\C06C3.8, Cele\C41H7.4, Cele\C14E2.6, Cele\C40H1.2, Cele\Y51H4A.5, Cele\T10B5.7, Cele\sco-1, Cele\C41H7.6, Cele\C08A9.6, Cele\B0454.9" "Xtro\pnliprp2, Xtro\LOC100486161, Xtro\LOC394967, Xtro\pnliprp2, Xtro\pnliprp3" "Mmus\Lipi, Mmus\Sco2, Mmus\Pnlip, Mmus\Sco1, Mmus\Pla1a, Mmus\Liph, Mmus\Pnliprp1, Mmus\Pnliprp2" "Hsap\LIPI, Hsap\PLA1A, Hsap\PNLIPRP1, Hsap\PNLIPRP2, Hsap\PNLIP, Hsap\SCO2, Hsap\PNLIPRP3, Hsap\SCO1, Hsap\LIPH" viable FBgn0261606 RpL27A Ribosomal protein L27A http://flybase.org/reports/FBgn0261606 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001196, InterPro:IPR030878 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype" large ribosomal subunit ; GO:0015934 | inferred from electronic annotation with InterPro:IPR030878 ribosome ; GO:0005840 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "RpL27A, CG15442, M(2)24F, RpL27a, rpL27a, anon-EST:Posey257, RpL27a2, RpL27Ab, RpL27Aa, M(2)24F-1, M(2)z, M, M(2L)z, M(2)Z, Mz, M[[z]], l(2)24Fb, l(2)24EFh, Rp L27A" "IPR030878:Ribosomal protein L15, IPR001196:Ribosomal protein L15, conserved site, IPR021131:Ribosomal protein L18e/L15P" CG15442 11-Aug-17 DroID_v2017_08 Drer\rpl27a Scer\RPL28 Cele\Y37E3.8 Xtro\rpl27a Mmus\Rpl27a Hsap\RPL27A " adult stage , embryonic stage && larval stage && adult stage " " adult head

, organism

" DRSC00781 IEK -1.440376425 -2.156419647 0.436583058 -5.317921167 0.514185084 2.521196621 FBgn0032505 CG16826 - http://flybase.org/reports/FBgn0032505 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG16826 - CG16826 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0020272 mst misato http://flybase.org/reports/FBgn0020272 FBgn0001566 protein_coding_gene GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008 mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay "CG1424, LB20, l(1)LB20, LB-20, l(1)LB14, lLB14, l(1)19Fg, mst" "IPR029209:DML1/Misato, tubulin domain, IPR003008:Tubulin/FtsZ, GTPase domain, IPR019605:Misato Segment II tubulin-like domain" CG1424 11-Aug-17 DroID_v2017_08 Drer\msto1 Scer\DML1 - Xtro\msto1 Mmus\Msto1 Hsap\MSTO1 " larval stage , embryonic stage -- adult stage , adult stage | female , adult stage , pupal stage | late , adult stage && oogenesis stage " " embryonic/larval fat body

, imaginal disc

, adult brain

, brain

, ovary

" "viable,fertile,lethal,recessive,cell lethal,germline clone,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,wild-type" mitotic spindle FBgn0029868 ND-B16.6 NADH dehydrogenase (ubiquinone) B16.6 subunit http://flybase.org/reports/FBgn0029868 protein_coding_gene NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:Q9P0J0 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:Q9P0J0" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:Q9P0J0 "CG3446, NB6M, ND-B16.6" IPR009346:GRIM-19 CG3446 11-Aug-17 DroID_v2017_08 Drer\ndufa13 - Cele\C34B2.8 Xtro\ndufa13 Mmus\Ndufa13 "Hsap\YJEFN3, Hsap\NDUFA13" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC26200 K -0.569773858 0.406801043 0.155061306 -0.151319083 0.056470529 -1.63279106 FBgn0044088 E(rst)E146 E(rst)E146 http://flybase.org/reports/FBgn0044088 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E146, E(rst)E146" - - 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035162 Sf3b3 Splicing factor 3b subunit 3 http://flybase.org/reports/FBgn0035162 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000068443 "neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000068443 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004513 inferred from sequence or structural similarity with protein_id:CAB56791 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" U2 snRNP ; GO:0005686 | colocalizes_with inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000004513 inferred from sequence or structural similarity with protein_id:CAB56791 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000004513 inferred from sequence or structural similarity with protein_id:CAB56791 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG13900, SF3B3, Sf3b3" "IPR004871:Cleavage/polyadenylation specificity factor, A subunit, C-terminal, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG13900 11-Aug-17 DroID_v2017_08 Drer\sf3b3 Scer\RSE1 Cele\teg-4 Xtro\sf3b3 Mmus\Sf3b3 Hsap\SF3B3 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC08370 I -0.080701333 1.99189753 0.522481965 0.911042779 -1.439788591 -0.749702092 FBgn0014133 bif bifocal http://flybase.org/reports/FBgn0014133 - protein_coding_gene actin filament binding ; GO:0051015 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from direct assay actin binding ; GO:0003779 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype negative regulation of axon extension ; GO:0030517 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG1822, bif, Bif" IPR015943:WD40/YVTN repeat-like-containing domain CG1822 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-12h9.6, Drer\tmem57a, Drer\tmem57b" - Cele\maco-1 - Mmus\Tmem57 Hsap\TMEM57 adult stage adult head

" embryonic stage | late , embryonic stage | stage >=16 , embryonic stage | stage >=14 , embryonic stage | early , embryonic stage | stage 13-17 , larval stage | third instar , pupal stage " " embryonic central nervous system

, longitudinal connective

, posterior commissure

, anterior commissure

, neuron

, morphogenetic furrow | posterior to

, photoreceptor cell R1--8

, rhabdomere

" "viable,fertile,neuroanatomy defective,meiotic cell cycle defective,dominant,visible,recessive" "macrochaeta,photoreceptor cell R2 & axon[-],photoreceptor cell R3 & axon[-],photoreceptor cell R4 & axon[-],photoreceptor cell R5 & axon[-],eye,rhabdomere,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,lamina anlage glial cell,photoreceptor cell R1 & axon,photoreceptor cell R6 & axon,photoreceptor cell R7 & axon,photoreceptor cell R8 & axon,lamina,interommatidial bristle,supernumerary,ommatidium,actin filament,embryonic/larval optic neuropil,photoreceptor cell R1 & axonGMR.PF,photoreceptor cell R2 & axonGMR.PF,photoreceptor cell R3 & axonGMR.PF,photoreceptor cell R4 & axonGMR.PF,photoreceptor cell R5 & axonGMR.PF,photoreceptor cell R6 & axonGMR.PF,lamina plexus,medulla,photoreceptor cell,photoreceptor cell R7 & axonsev.PM181" FBgn0035113 pyx pyrexia http://flybase.org/reports/FBgn0035113 protein_coding_gene calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity cation channel activity ; GO:0005261 | inferred from direct assay ion transmembrane transport ; GO:0034220 | inferred from electronic annotation with InterPro:IPR030288 calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity calcium ion transport ; GO:0006816 | inferred from direct assay potassium ion transport ; GO:0006813 | inferred from direct assay protein heterotetramerization ; GO:0051290 | non-traceable author statement negative gravitaxis ; GO:0048060 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred by curator from GO:0005261 cation channel complex ; GO:0034703 | inferred from direct assay "CG17142, CT33412, pyx, Pyx, dTRPA2, trpA2" "IPR002110:Ankyrin repeat, IPR005821:Ion transport domain, IPR030288:Transient receptor potential ankyrin 1 channel, IPR020683:Ankyrin repeat-containing domain" CG17142 11-Aug-17 DroID_v2017_08 "Drer\asb11, Drer\asb13a.1, Drer\asb12a, Drer\asb5a, Drer\zdhhc17, Drer\asb16, Drer\asb10, Drer\trpa1b, Drer\zdhhc13, Drer\anks1b, Drer\trpa1a, Drer\asb5b" "Scer\YAR1, Scer\AKR1, Scer\AKR2" "Cele\trpa-1, Cele\T28D6.4, Cele\dhhc-14, Cele\dhhc-13, Cele\unc-44" "Xtro\trpa1, Xtro\asb1, Xtro\asb9, Xtro\asb16, Xtro\asb12" "Mmus\Ankrd44, Mmus\Ank1, Mmus\Zdhhc17, Mmus\Asb1, Mmus\Asb12, Mmus\Asb5, Mmus\Ank2, Mmus\Asb16, Mmus\Trpa1, Mmus\Ank3, Mmus\Sowahd, Mmus\Asb3, Mmus\Asb9, Mmus\Asb13, Mmus\Sowahc, Mmus\Ankrd35, Mmus\Asb8, Mmus\Asb11, Mmus\Zdhhc13, Mmus\Asb10" "Hsap\TRPA1, Hsap\ASB11, Hsap\ANK1, Hsap\SOWAHD, Hsap\ANKRD44, Hsap\ANKRD35, Hsap\ASB13, Hsap\SOWAHC, Hsap\ASB1, Hsap\ZDHHC17, Hsap\CTTNBP2, Hsap\ZDHHC13, Hsap\ANK3, Hsap\ASB12, Hsap\ANK2, Hsap\ASB9, Hsap\ASB5" "viable,gravitaxis defective,paralytic,heat sensitive,thermotaxis behavior defective,neurophysiology defective" DRSC08510 K 0.428476799 0.367704321 0.231284726 0.135431481 -1.596038983 -0.271680622 FBgn0021814 Vps28 Vacuolar protein sorting 28 http://flybase.org/reports/FBgn0021814 FBgn0033254 protein_coding_gene protein complex binding ; GO:0032403 | inferred from biological aspect of ancestor with PANTHER:PTN000309785 protein binding ; GO:0005515 | inferred from physical interaction with TSG101 autophagosome maturation ; GO:0097352 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from mutant phenotype regulation of multivesicular body size ; GO:0010796 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred by curator from GO:0000813 neuron remodeling ; GO:0016322 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype negative regulation of growth of symbiont in host ; GO:0044130 | inferred from mutant phenotype protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043328 | inferred from biological aspect of ancestor with PANTHER:PTN000309785 ESCRT I complex ; GO:0000813 | inferred from direct assay ESCRT I complex ; GO:0000813 | inferred from sequence or structural similarity with SGD:S000005986 "DmVps28, vps28, l(2)k16503, CG12770, Vps28, dVps28, ESCRT-II, ESCRT-I, dvps28, Dvps28" "IPR007143:Vacuolar protein sorting-associated, VPS28, IPR017898:Vacuolar protein sorting-associated, VPS28, N-terminal, IPR017899:Vacuolar protein sorting-associated, VPS28, C-terminal" CG12770 11-Aug-17 DroID_v2017_08 Drer\vps28 Scer\VPS28 Cele\vps-28 Xtro\vps28 Mmus\Vps28 Hsap\VPS28 "lethal,recessive,cell shape defective,germline clone,male sterile,tumorigenic" "ommatidium,somatic clone,eye photoreceptor cell,actin cytoskeleton | embryonic stage | germline clone,pole cell,germline clone,nucleus | embryonic stage | germline clone,autophagic vacuole | conditional | somatic clone,fat body,conditional,spermatid,spermatozoon,eye,egg chamber,plasma membrane | somatic clone,actin filament | somatic clone,embryonic/larval digestive system,epithelium,interfollicle cell,female germline cyst" FBgn0040190 l(1)G0197 lethal (1) G0197 http://flybase.org/reports/FBgn0040190 gene - - - l(1)G0197 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0029932 CG4607 - http://flybase.org/reports/FBgn0029932 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG4607 "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG4607 11-Aug-17 DroID_v2017_08 "Drer\LOC101882338, Drer\slc2a8, Drer\slc2a6, Drer\slc2a10, Drer\slc2a12, Drer\slc2a13b" "Scer\MPH3, Scer\VBA5, Scer\HXT13, Scer\HXT1, Scer\HXT9, Scer\HXT17, Scer\ENB1, Scer\SNF3, Scer\HXT2, Scer\YFL040W, Scer\HXT11, Scer\MAL11, Scer\VBA2, Scer\RGT2, Scer\YDR387C, Scer\HXT5, Scer\HXT3, Scer\YDL199C, Scer\GEX1, Scer\HXT4, Scer\HXT16, Scer\HXT7, Scer\HXT6, Scer\HXT8, Scer\MPH2, Scer\VBA1, Scer\GAL2, Scer\VBA3, Scer\HXT10, Scer\YMR279C, Scer\ITR1, Scer\MAL31, Scer\VBA4, Scer\HXT14, Scer\AZR1, Scer\STL1, Scer\GEX2, Scer\ATR1, Scer\ITR2, Scer\SGE1, Scer\HXT15" "Cele\F48E3.2, Cele\hmit-1.2" "Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a10, Xtro\slc2a12" "Mmus\Slc2a12, Mmus\Slc2a10, Mmus\Slc2a13, Mmus\Slc2a6, Mmus\Slc2a8" "Hsap\SLC2A10, Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SLC2A8, Hsap\SLC2A12" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0002329 l(3)87Aa lethal (3) 87Aa http://flybase.org/reports/FBgn0002329 - gene - - - "ck8, l(3)ck8, l(3)87Aa" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0053822 His1:CG33822 His1:CG33822 http://flybase.org/reports/FBgn0053822 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33822, His1:CG33822" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33822 11-Aug-17 DroID_v2017_08 "Drer\zgc:110216, Drer\h1fx, Drer\zgc:153405, Drer\si:dkey-261m9.12, Drer\si:ch211-113a14.24, Drer\histh1l, Drer\si:ch73-36p18.1, Drer\h1m, Drer\si:dkey-108k21.21, Drer\si:dkey-108k21.14, Drer\si:dkey-108k21.10, Drer\h1f0, Drer\si:ch1073-159d7.7, Drer\zgc:163061, Drer\zgc:110425" Scer\HHO1 "Cele\hil-3, Cele\hil-1, Cele\his-24, Cele\hil-2, Cele\hil-4, Cele\hil-5, Cele\hil-6" - "Mmus\Hist1h1b, Mmus\Hist1h1e, Mmus\Hils1, Mmus\H1foo, Mmus\H1fx, Mmus\H1fnt, Mmus\Hist1h1a, Mmus\Hist1h1c, Mmus\Hist1h1d, Mmus\Hist1h1t" "Hsap\H1FX, Hsap\HIST1H1E, Hsap\HIST1H1D, Hsap\H1F0, Hsap\HIST1H1A, Hsap\HIST1H1T, Hsap\HIST1H1B, Hsap\H1FNT, Hsap\H1FOO, Hsap\HIST1H1C" FBgn0035078 Tpc2 Thiamine pyrophosphate carrier protein 2 http://flybase.org/reports/FBgn0035078 protein_coding_gene thiamine transmembrane transporter activity ; GO:0015234 | inferred from biological aspect of ancestor with PANTHER:PTN000756668 thiamine pyrophosphate-transporting ATPase activity ; GO:0015619 | inferred from sequence or structural similarity with Tpc1 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 thiamine pyrophosphate transport ; GO:0030974 | inferred from biological aspect of ancestor with PANTHER:PTN000756668 thiamine pyrophosphate transport ; GO:0030974 | inferred from sequence or structural similarity with Tpc1 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000756668 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000756668 "Tpc2, CG2857, DmTpc2" "IPR002067:Mitochondrial carrier protein, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG2857 11-Aug-17 DroID_v2017_08 "Drer\slc25a43, Drer\slc25a19, Drer\slc25a16" "Scer\YPR011C, Scer\LEU5, Scer\TPC1" "Cele\hpo-12, Cele\C47E12.2, Cele\F47B8.10" "Xtro\slc25a42, Xtro\slc25a19, Xtro\slc25a43" "Mmus\Slc25a19, Mmus\Slc25a43, Mmus\Slc25a16, Mmus\Slc25a42" "Hsap\SLC25A42, Hsap\SLC25A19, Hsap\SLC25A43, Hsap\SLC25A16" viable FBgn0039617 DIP-gamma Dpr-interacting protein gamma http://flybase.org/reports/FBgn0039617 protein_coding_gene - establishment of synaptic specificity at neuromuscular junction ; GO:0007529 | inferred from direct assay synapse organization ; GO:0050808 | inferred from expression pattern photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype regulation of neuromuscular junction development ; GO:1904396 | inferred from mutant phenotype neuron projection membrane ; GO:0032589 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CT34248, anon-WO0140519.196, CG14521, 14521, DIP-gamma" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain" CG14521 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-250k15.10, Drer\cxadr, Drer\esamb, Drer\ntm, Drer\si:ch211-9d9.7, Drer\negr1, Drer\si:ch211-215e19.3, Drer\f11r.2, Drer\igsf11, Drer\vsig8b, Drer\pigrl4.2, Drer\mxra8a, Drer\si:dkey-31e10.5, Drer\vsig8a, Drer\zgc:113337, Drer\jam2b, Drer\LOC100151468, Drer\f11r.1, Drer\mxra8b, Drer\zgc:110372, Drer\gpa33, Drer\lsamp, Drer\si:zfos-1011f11.1, Drer\zgc:153073, Drer\cxcr3.1, Drer\jam2a, Drer\si:dkey-65b12.12, Drer\opcml, Drer\jam3b, Drer\jam3a, Drer\esama" - Cele\rig-5 "Xtro\lsamp, Xtro\negr1, Xtro\ntm" "Mmus\Clmp, Mmus\Cd200, Mmus\Vsig8, Mmus\Vsig1, Mmus\Negr1, Mmus\Esam, Mmus\Igsf11, Mmus\Gm1123, Mmus\Opcml, Mmus\F11r, Mmus\Vsig2, Mmus\Jam2, Mmus\Mxra8, Mmus\Vsir, Mmus\Iglon5, Mmus\Cxadr, Mmus\Lsamp, Mmus\Gpa33, Mmus\Btnl10, Mmus\Hepacam2, Mmus\Jam3, Mmus\Igsf5, Mmus\Ntm" "Hsap\JAM2, Hsap\ESAM, Hsap\NTM, Hsap\VSIG1, Hsap\GPA33, Hsap\CXADR, Hsap\IGLON5, Hsap\F11R, Hsap\MXRA8, Hsap\NEGR1, Hsap\C10orf54, Hsap\OPCML, Hsap\CLMP, Hsap\LSAMP, Hsap\IGSF11, Hsap\CD200, Hsap\JAM3, Hsap\IGSF5, Hsap\CD226, Hsap\VSIG2, Hsap\VSIG8, Hsap\C1orf204" FBgn0061362 CG33785 - http://flybase.org/reports/FBgn0061362 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR012164 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001222" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR001529, InterPro:IPR012164 mRNA cleavage ; GO:0006379 | inferred from electronic annotation with InterPro:IPR034014" - "CG33005, CG10438a, CG10438, CG30144, CG33005-ORFA, CG33785, Dromel_CG33786_FBtr0091786_uORF, CG33005ORFA" "IPR034014:Pol III subunit C11, C-terminal zinc ribbon, IPR001222:Zinc finger, TFIIS-type, IPR001529:DNA-directed RNA polymerase, M/15kDa subunit, IPR012164:DNA-directed RNA polymerase subunit/transcription factor S, IPR019761:DNA-directed RNA polymerase M, 15kDa subunit, conserved site" CG33785 11-Aug-17 DroID_v2017_08 "Drer\yrdc, Drer\polr3k" Scer\RPC11 "Cele\Y48C3A.18, Cele\rpc-11" "Xtro\yrdc, Xtro\polr3k" "Mmus\Polr3k, Mmus\Yrdc" "Hsap\POLR3K, Hsap\YRDC" FBgn0035236 CG12004 - http://flybase.org/reports/FBgn0035236 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 defense response to fungus ; GO:0050832 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 "anon-EST:fe3A8, CG12004" IPR005178:Organic solute transporter subunit alpha/Transmembrane protein 184 CG12004 11-Aug-17 DroID_v2017_08 "Drer\tmem184ba, Drer\tmem184a, Drer\tmem184c, Drer\si:dkey-16n15.6, Drer\slc51a, Drer\tmem184bb, Drer\si:dkey-217f16.5" Scer\YKR051W "Cele\osta-1, Cele\F40E10.6, Cele\osta-3, Cele\osta-2" "Xtro\tmem184b, Xtro\tmem184a, Xtro\tmem184c" "Mmus\Tmem184c, Mmus\Tmem184a, Mmus\Slc51a, Mmus\Tmem184b" "Hsap\TMEM184A, Hsap\SLC51A, Hsap\TMEM184B, Hsap\TMEM184C" "immune response defective,viable,fertile" "hemocyte,plasmatocyte" DRSC08215 E 1.330203109 0.536979834 1.850553401 -0.250129487 -1.205167277 -0.471144664 FBgn0037339 Pi4KIIalpha Pi4KIIalpha http://flybase.org/reports/FBgn0037339 protein_coding_gene 1-phosphatidylinositol 4-kinase activity ; GO:0004430 | inferred from direct assay protein localization to organelle ; GO:0033365 | inferred from mutant phenotype phosphatidylinositol phosphorylation ; GO:0046854 | inferred from direct assay endosome organization ; GO:0007032 | inferred from mutant phenotype secretory granule localization ; GO:0032252 | inferred from mutant phenotype secretory granule organization ; GO:0033363 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype trans-Golgi network ; GO:0005802 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN000305230 plasma membrane ; GO:0005886 | inferred from direct assay "CG2929, PI4KIIalpha, Pi4KIIalpha, PI4KII, PI4KIIbeta, Pi4KIIa" "IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain" CG2929 11-Aug-17 DroID_v2017_08 "Drer\pi4k2a, Drer\pi4k2b" Scer\LSB6 "Cele\ZC8.6, Cele\C56A3.8" "Xtro\pi4k2a, Xtro\pi4k2b" "Mmus\Pi4k2a, Mmus\Pi4k2b" "Hsap\PI4K2B, Hsap\HOGA1, Hsap\PI4K2A" "viable,fertile" "rhabdomereGMR.PF,Golgi apparatus" FBgn0030743 CG9921 - http://flybase.org/reports/FBgn0030743 protein_coding_gene - - - CG9921 "IPR007667:Hypoxia induced protein, domain" CG9921 11-Aug-17 DroID_v2017_08 "Drer\higd2a, Drer\higd1a" Scer\RCF1 "Cele\T20D3.6, Cele\M05D6.5" "Xtro\higd1c, Xtro\higd2a, Xtro\higd1b, Xtro\higd1a" "Mmus\Higd2a, Mmus\Higd1b, Mmus\Higd1c, Mmus\Higd1a" "Hsap\HIGD2A, Hsap\HIGD1B, Hsap\HIGD1A, Hsap\HIGD1C" viable DRSC20220 K -0.394071829 0.91068287 -1.137003757 0.663211691 1.181299115 -1.706965137 FBgn0051729 CG31729 - http://flybase.org/reports/FBgn0051729 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006539 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR006539 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from sequence or structural similarity with SGD:S000000024 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 "endocytosis ; GO:0006897 | inferred from biological aspect of ancestor with PANTHER:PTN000642870 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000642870 phospholipid translocation ; GO:0045332 | inferred from sequence or structural similarity with SGD:S000000024" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR006539 integral component of membrane ; GO:0016021 | inferred from sequence model trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000642870 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000642870" "CG6263, CG16823, CG31729, DmCG31729, P4-ATPase" "IPR001757:P-type ATPase, IPR006539:P-type ATPase, subfamily IV, IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site, IPR030355:Probable phospholipid-transporting ATPase IIB, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N, IPR032630:P-type ATPase, C-terminal, IPR032631:P-type ATPase, N-terminal" CG31729 11-Aug-17 DroID_v2017_08 Drer\atp9b Scer\NEO1 "Cele\tat-5, Cele\tat-6" "Xtro\atp9a, Xtro\atp9b" "Mmus\Atp9a, Mmus\Atp9b" "Hsap\ATP9A, Hsap\ATP9B" viable FBgn0032171 CG5846 - http://flybase.org/reports/FBgn0032171 protein_coding_gene transcription cofactor activity ; GO:0003712 | inferred from biological aspect of ancestor with PANTHER:PTN001538048 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001538048 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001538048 CG5846 "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG5846 11-Aug-17 DroID_v2017_08 "Drer\rfxank, Drer\ankra2, Drer\nkpd1, Drer\ankef1a, Drer\ankef1b, Drer\nfkbiz, Drer\zgc:113279, Drer\kidins220a, Drer\kidins220b" - - "Xtro\kidins220, Xtro\ankef1, Xtro\rfxank, Xtro\ankra2, Xtro\nkpd1" "Mmus\Ankra2, Mmus\Nfkbid, Mmus\Nfkbiz, Mmus\Rfxank, Mmus\Nkpd1, Mmus\Ankef1, Mmus\Kidins220" "Hsap\ANKRA2, Hsap\RFXANK, Hsap\NFKBID, Hsap\ANKEF1, Hsap\NKPD1, Hsap\KIDINS220, Hsap\NFKBIZ" "viable,body color defective" mesothoracic tergum FBgn0020258 ppk pickpocket http://flybase.org/reports/FBgn0020258 - protein_coding_gene acid-sensing ion channel activity ; GO:0044736 | inferred from mutant phenotype sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype larval turning behavior ; GO:0035179 | inferred from mutant phenotype negative regulation of feeding behavior ; GO:2000252 | inferred from mutant phenotype behavioral response to pain ; GO:0048266 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception of pain ; GO:0050966 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception of pain ; GO:0050966 | inferred from expression pattern mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 dendrite membrane ; GO:0032590 | inferred from direct assay "ppk1, PPK1, dmdNaCl, PPK, dmdNaC1, BG:DS06238.1, pkt, mdNaC1, CG3478, ppk" "IPR001873:Epithelial sodium channel, IPR020903:Epithelial sodium channel, conserved site" CG3478 11-Aug-17 DroID_v2017_08 "Drer\smarcd3a, Drer\asic2, Drer\asic4b, Drer\asic1a, Drer\asic4a, Drer\smarcd1, Drer\asic1c, Drer\smarcd3b, Drer\asic1b" "Scer\RSC6, Scer\SNF12" "Cele\del-6, Cele\swsn-2.2, Cele\asic-2, Cele\deg-1, Cele\delm-1, Cele\mec-10, Cele\ham-3, Cele\acd-1, Cele\acd-4, Cele\acd-5, Cele\unc-8, Cele\del-8, Cele\flr-1, Cele\delm-2, Cele\mec-4, Cele\acd-3" "Xtro\scnn1d, Xtro\asic1, Xtro\scnn1b, Xtro\asic4, Xtro\scnn1g, Xtro\asic5, Xtro\scnn1a" "Mmus\Asic5, Mmus\Asic3, Mmus\Scnn1b, Mmus\Asic2, Mmus\Smarcd3, Mmus\Scnn1a, Mmus\Scnn1g, Mmus\Smarcd1, Mmus\Asic1, Mmus\Asic4, Mmus\Smarcd2" "Hsap\SMARCD2, Hsap\SMARCD3, Hsap\ASIC2, Hsap\ASIC4, Hsap\ASIC5, Hsap\SCNN1A, Hsap\ASIC1, Hsap\SCNN1G, Hsap\SCNN1D, Hsap\ASIC3, Hsap\SMARCD1, Hsap\SCNN1B" " embryonic stage | stage 17 , larval stage | early , embryonic stage , embryonic stage -- adult stage , larval stage , adult stage " " embryonic peripheral nervous system | restricted

, multidendritic neuron | subset

, peripheral nervous system | restricted

, dendritic arborising neuron | subset

" " embryonic stage | stage 17 , larval stage | early " " multidendritic neuron | subset

, peripheral nervous system | restricted

, dendritic arborising neuron | subset

" "locomotor behavior defective,pain response defective,neurophysiology defective,behavior defective,small body,large body,touch sensitivity defective" class IV dendritic arborizing neuron FBgn0032397 Tom70 Translocase of outer membrane 70 http://flybase.org/reports/FBgn0032397 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O94826 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O94826 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from sequence or structural similarity with UniProtKB:O94826 "dtom70, CG6756, Tom70, RE66761p" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR013105:Tetratricopeptide repeat 2" CG6756 11-Aug-17 DroID_v2017_08 "Drer\aip, Drer\tomm34, Drer\tomm70a" "Scer\TOM71, Scer\TOM70, Scer\CNS1" "Cele\Y37E3.1, Cele\C17G10.2, Cele\C56C10.10" "Xtro\tomm70a, Xtro\aip, Xtro\spag1" "Mmus\Aip, Mmus\Tomm34, Mmus\Spag1, Mmus\Tomm70a" "Hsap\SPAG1, Hsap\AIP, Hsap\TOMM34, Hsap\TOMM70" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033912 RpS23 Ribosomal protein S23 http://flybase.org/reports/FBgn0033912 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR005680, InterPro:IPR006032 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 centrosome organization ; GO:0051297 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype" small ribosomal subunit ; GO:0015935 | inferred from electronic annotation with InterPro:IPR005680 cytosol ; GO:0005829 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CG8415, CT24703, anon-EST:Posey63, anon-EST:Posey158, RpS23, Rp S23, RPS23" "IPR005680:Ribosomal protein S23, eukaryotic/archaeal, IPR006032:Ribosomal protein S12/S23, IPR012340:Nucleic acid-binding, OB-fold" CG8415 11-Aug-17 DroID_v2017_08 Drer\rps23 "Scer\RPS23B, Scer\RPS23A" Cele\rps-23 Xtro\rps23 Mmus\Rps23 Hsap\RPS23 lethal DRSC07169 IEK -0.260748326 -1.527367747 0.563429869 -3.766780465 2.069063174 2.22837979 FBgn0039229 Saf-B Scaffold attachment factor B http://flybase.org/reports/FBgn0039229 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN001812651 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN001812651 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001812651 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nuclear matrix ; GO:0016363 | inferred from direct assay "SAF-B, LD22822, cg6995, CG6995, Saf-B, saf-b, SAFB" "IPR000504:RNA recognition motif domain, IPR003034:SAP domain" CG6995 11-Aug-17 DroID_v2017_08 "Drer\safb, Drer\sltm" - "Cele\F32B4.4, Cele\rsp-8" "Xtro\safb, Xtro\tra2b, Xtro\sltm, Xtro\tra2a" "Mmus\Safb, Mmus\Tra2b, Mmus\Tra2a, Mmus\Safb2, Mmus\Sltm" "Hsap\TRA2A, Hsap\TRA2B, Hsap\SLTM, Hsap\SAFB, Hsap\SAFB2" DRSC16167 IE 2.744801637 3.325299303 2.302410154 0.789484686 -0.0043265 0.448012631 FBgn0266019 rudhira rudhira http://flybase.org/reports/FBgn0266019 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to starvation ; GO:0042594 | inferred from biological aspect of ancestor with PANTHER:PTN000327724 macropinocytosis ; GO:0044351 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG32663, rudhira, Drudh, DRudh, Rudh, CG43154, CG1905, clone 2.41, anon-EST:Liang-2.41, CG32662" "IPR022175:Breast carcinoma amplified sequence 3, IPR015943:WD40/YVTN repeat-like-containing domain" CG43154 11-Aug-17 DroID_v2017_08 "Drer\bcas3, Drer\map2" - Cele\F56C9.10 Xtro\bcas3 "Mmus\Bcas3, Mmus\Map2" "Hsap\BCAS3, Hsap\MAP2" FBgn0031871 Fgop2 Fibroblast growth factor receptor 1 oncogene partner 2 http://flybase.org/reports/FBgn0031871 protein_coding_gene - positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D - "CG10158, FGOP2, FGFR1OP2, Fgop2" IPR008555:Suppressor of IKBKE 1 CG10158 11-Aug-17 DroID_v2017_08 "Drer\fgfr1op2, Drer\sike1" - Cele\C14B1.8 "Xtro\fgfr1op2, Xtro\sike1" "Mmus\Fgfr1op2, Mmus\Sike1" "Hsap\SIKE1, Hsap\FGFR1OP2" "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive" FBgn0065932 l(2)SH0133 lethal (2) SH0133 http://flybase.org/reports/FBgn0065932 gene - - - "l(2)SH0133, l(2)SH2 0133" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0266162 CR44868 - http://flybase.org/reports/FBgn0266162 non_protein_coding_gene - - - CR44868 - CR44868 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0266922 d::Zyx - http://flybase.org/reports/FBgn0266922 engineered_fusion_gene - - - "d::Zyx, Zyx:Dachs" - - 11-Aug-17 DroID_v2017_08 - - - - - - cell polarity defective "wing,wing hair" FBgn0031975 Tg Transglutaminase http://flybase.org/reports/FBgn0031975 protein_coding_gene protein-glutamine gamma-glutamyltransferase activity ; GO:0003810 | inferred from mutant phenotype "peptide cross-linking ; GO:0018149 | inferred from electronic annotation with InterPro:IPR001102, InterPro:IPR008958 innate immune response ; GO:0045087 | inferred from mutant phenotype hemolymph coagulation ; GO:0042381 | inferred from mutant phenotype" - "TG, Tg, dTG, CG7356, tg, dTG-alpha" "IPR001102:Transglutaminase, N-terminal, IPR002931:Transglutaminase-like, IPR008958:Transglutaminase, C-terminal, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR023608:Protein-glutamine gamma-glutamyltransferase, eukaryota" CG7356 11-Aug-17 DroID_v2017_08 "Drer\tgm2a, Drer\tgm1l2, Drer\tgm1, Drer\si:ch1073-138d10.2, Drer\LOC558353, Drer\tgm2l, Drer\tgm2b, Drer\tgm8, Drer\tgm1l1, Drer\f13a1a.1, Drer\tgm5l, Drer\tgm1l4, Drer\tgm1l3, Drer\f13a1b, Drer\tgm1l5" - - "Xtro\tgm4, Xtro\tgm1, Xtro\tgm5, Xtro\tgm2, Xtro\tgm6, Xtro\epb42, Xtro\tgm3.2" "Mmus\Tgm6, Mmus\Tgm3, Mmus\Epb42, Mmus\Tgm4, Mmus\Tgm7, Mmus\F13a1, Mmus\Tgm5, Mmus\Tgm2, Mmus\Tgm1" "Hsap\TGM3, Hsap\TGM4, Hsap\TGM5, Hsap\TGM1, Hsap\TGM2, Hsap\F13A1, Hsap\TGM6, Hsap\EPB42, Hsap\TGM7" "visible,short lived,partially lethal - majority die,some die during pupal stage,viable" "eye,crossvein,wing,tergite,ommatidium,interommatidial bristle" DRSC29048 K 0.418224094 -0.501149341 -0.235865979 -0.03854332 2.008931023 -0.763295694 FBgn0019982 Gs1l GS1-like http://flybase.org/reports/FBgn0019982 - protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 wound healing ; GO:0042060 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 "GS1l, CG15441, Gs1l, gs1-like, 19864674" "IPR023198:Phosphoglycolate phosphatase, domain 2, IPR006439:HAD hydrolase, subfamily IA, IPR023214:HAD-like domain" CG15441 11-Aug-17 DroID_v2017_08 Drer\pudp "Scer\YKL033W-A, Scer\DOG2, Scer\DOG1, Scer\GPP1, Scer\GPP2" Cele\R151.10 Xtro\pudp Mmus\Hdhd1a Hsap\PUDP adult stage viable FBgn0038331 Ccm3 Cerebral cavernous malformation 3 http://flybase.org/reports/FBgn0038331 protein_coding_gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - "CG5073, Ccm3" IPR009652:Programmed cell death protein 10 CG5073 11-Aug-17 DroID_v2017_08 "Drer\pdcd10b, Drer\pdcd10a" - Cele\ccm-3 Xtro\pdcd10 Mmus\Pdcd10 Hsap\PDCD10 "viable,lethal" terminal tracheal cell | third instar larval stage FBgn0053337 CG33337 - http://flybase.org/reports/FBgn0053337 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33337 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG33337 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-54, Cele\oac-20, Cele\oac-14, Cele\ndg-4, Cele\oac-39, Cele\oac-3, Cele\oac-46, Cele\oac-32, Cele\nrf-6, Cele\oac-53, Cele\oac-55, Cele\oac-7, Cele\rhy-1, Cele\oac-9, Cele\oac-31, Cele\oac-5, Cele\oac-50, Cele\oac-6" Xtro\LOC101732251 Mmus\Oacyl - FBgn0034908 CG5543 - http://flybase.org/reports/FBgn0034908 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "anon-WO0118547.181, CG5543" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG5543 11-Aug-17 DroID_v2017_08 Drer\wdr70 Scer\CRN1 Cele\gad-1 Xtro\wdr70 Mmus\Wdr70 Hsap\WDR70 "lethal,neuroanatomy defective,partially lethal - majority die" "embryonic/larval neuroblast,ganglion mother cell" FBgn0032853 CG10651 - http://flybase.org/reports/FBgn0032853 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "CG10651, 38C.2" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain" CG10651 11-Aug-17 DroID_v2017_08 "Drer\crispld1a, Drer\crispld1b, Drer\r3hdml, Drer\glipr2l, Drer\glipr1b, Drer\LOC101883528, Drer\LOC100536500, Drer\glipr2, Drer\crispld2, Drer\pi15b, Drer\pi15a" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\scl-19, Cele\scl-13, Cele\vap-2, Cele\scl-2, Cele\scl-9, Cele\scl-17, Cele\scl-11, Cele\scl-15, Cele\scl-21, Cele\scl-18, Cele\scl-6, Cele\scl-8, Cele\scl-23, Cele\scl-1, Cele\scl-5, Cele\scl-7, Cele\scl-14, Cele\scl-3, Cele\scl-10, Cele\scl-20, Cele\scl-12" "Xtro\MGC108118, Xtro\crispld2, Xtro\r3hdml, Xtro\glipr2, Xtro\crisp2, Xtro\pi15, Xtro\crisp3, Xtro\crisp1" "Mmus\Pi15, Mmus\Crisp1, Mmus\Pi16, Mmus\Glipr1l2, Mmus\Crisp3, Mmus\Clec18a, Mmus\Crisp2, Mmus\Crispld2, Mmus\Crisp4, Mmus\Glipr1, Mmus\Glipr2, Mmus\Crispld1, Mmus\R3hdml, Mmus\Glipr1l1" "Hsap\PI15, Hsap\GLIPR1, Hsap\GLIPR2, Hsap\CRISPLD1, Hsap\CRISP3, Hsap\R3HDML, Hsap\CRISPLD2, Hsap\CLEC18C, Hsap\CRISP2, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\PI16, Hsap\CRISP1, Hsap\CLEC18A, Hsap\CLEC18B" FBgn0033015 d4 d4 http://flybase.org/reports/FBgn0033015 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965 zinc ion binding ; GO:0008270 | inferred from sequence model" muscle organ development ; GO:0007517 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - "CG2682, dd4, d4, Dd4, D4" "IPR025750:Requiem/DPF N-terminal domain, IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019787:Zinc finger, PHD-finger, IPR029056:Ribokinase-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2682 11-Aug-17 DroID_v2017_08 "Drer\dpf2, Drer\dpf3, Drer\phf10, Drer\dpf2l, Drer\dpf1" - "Cele\dpff-1, Cele\phf-10" "Xtro\dpf3, Xtro\dpf2, Xtro\phf10" "Mmus\Zfp748, Mmus\Phf10, Mmus\Dpf2, Mmus\Dpf1, Mmus\Dpf3" "Hsap\DPF1, Hsap\DPF3, Hsap\PHF10, Hsap\DPF2" "partially lethal - majority die,some die during pupal stage" FBgn0003023 otu ovarian tumor http://flybase.org/reports/FBgn0003023 - protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:24949 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | NOT inferred from direct assay protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:24949 female germ-line sex determination ; GO:0019099 | non-traceable author statement positive regulation of DNA endoreduplication ; GO:0032877 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement protein deubiquitination ; GO:0016579 | NOT inferred from direct assay germ cell development ; GO:0007281 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "CG12743, otu, OTU, DROOTUA, fs(1)otu, fs(1)231, fs(1)23l, K, fs(1)M101, fs(1)jA265, Otu" "IPR002999:Tudor domain, IPR003323:OTU domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG12743 11-Aug-17 DroID_v2017_08 "Drer\zgc:92907, Drer\alg13" Scer\ALG13 Cele\algn-13 "Xtro\alg13, Xtro\otud4" "Mmus\Otud5, Mmus\Otud1, Mmus\Otud4, Mmus\Glt28d2, Mmus\Alg13" "Hsap\ALG13, Hsap\OTUD5, Hsap\OTUD1, Hsap\OTUD4" " oogenesis stage , spermatogenesis && adult stage , adult stage | male , oogenesis stage && adult stage | female , adult stage | female , pupal stage , pupal stage | late , oogenesis stage | stage S1-8 && adult stage | female " " egg chamber

, testis

, ovary

" " adult stage && oogenesis stage , oogenesis stage && adult stage | female " " germarium

, germarium region 2

, germarium region 1

, cystocyte

, ovary

, nurse cell

, oocyte

" "fertile,female sterile,recessive,female fertile,partially,wild-type,courtship behavior defective,female,female sterile germline-dependent,short lived,lethal,heat sensitive,male sterile,tumorigenic,partially lethal - majority die,some die during pupal stage" "egg chamber,ovary,nuclear chromosome,ovariole,nurse cell,egg,dorsal appendage,ectopic,nurse cell & nucleus,nurse cell & nuclear chromosome,germline cell,germarium,fusome,polytene chromosome band & nurse cell | ectopic,nurse cell ring canal,nurse follicle cell,oocyte" FBgn0038196 CG9922 - http://flybase.org/reports/FBgn0038196 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs28g09, BcDNA:RE55111, CG9922, dHYPK" - CG9922 11-Aug-17 DroID_v2017_08 Drer\hypk - Cele\F13G3.10 Xtro\hypk Mmus\Hypk Hsap\HYPK viable FBgn0003638 su(w[a]) suppressor of white-apricot http://flybase.org/reports/FBgn0003638 - protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR000061 mRNA 5'-splice site recognition ; GO:0000395 | inferred from biological aspect of ancestor with PANTHER:PTN000322792 - "SWAP, EG:BACR7A4.10, su(w), CG3019, su(wa), su(w[a])-2, su(w[a])-1, DmSWAP, su[wa], su(w[a]), su-w" "IPR000061:SWAP/Surp, IPR019147:Suppressor of white apricot N-terminal domain" CG3019 11-Aug-17 DroID_v2017_08 Drer\sfswap - Cele\swp-1 Xtro\sfswap Mmus\Sfswap Hsap\SFSWAP " embryonic stage | >3hr , embryonic stage | 0-3hr " "wild-type,visible,heat sensitive,viable" "pigment cell,heat sensitive,mesothoracic tergum" FBgn0069993 BG01862 BG01862 http://flybase.org/reports/FBgn0069993 gene - - - BG01862 - - 11-Aug-17 DroID_v2017_08 - - - - - - stress response defective FBgn0040899 CG17776 - http://flybase.org/reports/FBgn0040899 protein_coding_gene - - - CG17776 IPR029208:Cytochrome c oxidase assembly protein COX14 CG17776 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035196 CG9129 - http://flybase.org/reports/FBgn0035196 protein_coding_gene - - - CG9129 - CG9129 11-Aug-17 DroID_v2017_08 - - - - - - visible "antenna,leg,ectopic" FBgn0016983 smid smallminded http://flybase.org/reports/FBgn0016983 "FBgn0011034, FBgn0011393, FBgn0011406, FBgn0024837" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | non-traceable author statement" cellular response to starvation ; GO:0009267 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype - "l(3)j6B8, l(3)s2898, l(3)j8A6, CG8571, smid, Smid" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031996:NVL2, nucleolin binding domain" CG8571 11-Aug-17 DroID_v2017_08 Drer\nvl Scer\RIX7 Cele\mac-1 Xtro\nvl Mmus\Nvl Hsap\NVL embryonic stage -- adult stage "locomotor rhythm defective,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal,decreased cell number,somatic clone,neuroanatomy defective,viable,visible" "embryonic/larval central nervous system,embryonic/larval brain,neuroblast,central nervous system,somatic clone,ganglion mother cell,trichogen cell" FBgn0032248 Bug22 Basal body up regulated gene 22 http://flybase.org/reports/FBgn0032248 protein_coding_gene - "dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cilium organization ; GO:0044782 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 locomotion ; GO:0040011 | inferred from mutant phenotype protein polyglycylation ; GO:0018094 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from mutant phenotype positive regulation of flagellated sperm motility ; GO:1902093 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay sperm flagellum ; GO:0036126 | inferred from direct assay cilium ; GO:0005929 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG5343, Bug22" IPR007714:Cilia/flagella-associated protein 20/WDR90/C3orf67 CG5343 11-Aug-17 DroID_v2017_08 "Drer\cfap20, Drer\wdr90, Drer\zgc:162324" - Cele\C54C6.6 "Xtro\cfap20, Xtro\wdr90" "Mmus\4930452B06Rik, Mmus\Cfap20, Mmus\Wdr90" "Hsap\CFAP20, Hsap\C3orf67, Hsap\WDR90" "short lived,uncoordinated,locomotor behavior defective,gravitaxis defective,visible,male sterile,viable" "wing,primary spermatocyte,elongation stage spermatid,centriole,ciliary basal body,sperm flagellum,spermatid axoneme,cystic bulge,sperm individualization complex,waste bag,Nebenkern derivative" FBgn0027889 ball ballchen http://flybase.org/reports/FBgn0027889 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase binding ; GO:0019901 | inferred from physical interaction with UniProtKB:A8DYP0 protein kinase activity ; GO:0004672 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay histone threonine kinase activity ; GO:0035184 | inferred from direct assay" neuronal stem cell population maintenance ; GO:0097150 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 neurogenesis ; GO:0022008 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype histone phosphorylation ; GO:0016572 | inferred from direct assay regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype synaptonemal complex assembly ; GO:0007130 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype peptidyl-threonine phosphorylation ; GO:0018107 | inferred from direct assay flight ; GO:0060361 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype chromatin ; GO:0000785 | inferred from direct assay sarcomere ; GO:0030017 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 M band ; GO:0031430 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "CG6386, nhk-1, BcDNA:LD09009, NHK-1, VRK, ball, Ball, NHK1, BALL, trip" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG6386 11-Aug-17 DroID_v2017_08 "Drer\vrk2, Drer\csnk1e, Drer\vrk3, Drer\ttbk2b, Drer\csnk1a1, Drer\ttbk1a, Drer\csnk1db, Drer\vrk1, Drer\csnk1da, Drer\ttbk1b" "Scer\YCK1, Scer\YCK3, Scer\HRR25, Scer\YCK2, Scer\VHS1" "Cele\C44C10.7, Cele\vrk-1, Cele\prde-1, Cele\K08H2.5, Cele\C28A5.6, Cele\E02H4.6, Cele\F16B12.5, Cele\F16B12.7, Cele\D2045.5, Cele\K09C6.7, Cele\K09C6.8, Cele\K04C1.5" "Xtro\csnk1a1, Xtro\vrk1, Xtro\csnk1e, Xtro\vrk3, Xtro\ttbk2, Xtro\vrk2, Xtro\csnk1d" "Mmus\Ttbk1, Mmus\Vrk3, Mmus\Vrk1, Mmus\Csnk1a1, Mmus\Csnk1e, Mmus\Vrk2, Mmus\Csnk1d, Mmus\Ttbk2" "Hsap\CSNK1D, Hsap\VRK2, Hsap\VRK1, Hsap\VRK3, Hsap\TTBK2, Hsap\TTBK1, Hsap\CSNK1A1, Hsap\CSNK1E, Hsap\CSNK1A1L" "female sterile,meiotic cell cycle defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,mitotic cell cycle defective,male sterile,recessive,viable,female semi-fertile" "spindle,spindle pole,condensed chromosome,imaginal disc,embryonic/larval brain,karyosome,testis,polar body nucleus,maternal effect,stage S14 oocyte & meiotic metaphase I,stage S14 oocyte & meiotic metaphase ITl-I),embryonic/larval neuroblast,ganglion mother cell" FBgn0032906 RPA2 Replication protein A2 http://flybase.org/reports/FBgn0032906 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR014646 DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR014646 DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR014646 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR014646 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR014646 "153194_at, RPA2, dRPA2, CG9273, RpA2" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR012340:Nucleic acid-binding, OB-fold, IPR014646:Replication factor A protein 2, IPR014892:Replication protein A, C-terminal" CG9273 11-Aug-17 DroID_v2017_08 "Drer\obfc1, Drer\rpa2" Scer\RFA2 "Cele\rpa-4, Cele\rpa-2" Xtro\rpa2 "Mmus\Obfc1, Mmus\Rpa2" "Hsap\STN1, Hsap\RPA4, Hsap\RPA2" "lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "larval outer optic anlage,somatic clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,lamina anlage,medulla anlage,larval optic anlage" FBgn0004403 RpS14a Ribosomal protein S14a http://flybase.org/reports/FBgn0004403 "FBgn0002584, FBgn0025283, FBgn0025314, FBgn0025318, FBgn0025321, FBgn0029981, FBgn0066849, FBgn0066850" protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "RpS14a, S14, RpS14A, RpS14, RPS14A, rpS14A, anon-EST:Posey77, anon-EST:Posey154, anon-EST:Posey131, anon-EST:Posey115, CG1524, anon-WO03040301.138, anon-WO03040301.136, S14a, Rp S14a" - CG1524 11-Aug-17 DroID_v2017_08 "Drer\mrps11, Drer\rps14" "Scer\RPS14B, Scer\RPS14A" "Cele\mrps-11, Cele\rps-14" Xtro\rps14 "Mmus\Mrps11, Mmus\Rps14" "Hsap\MRPS11, Hsap\RPS14" DRSC18710 EK -1.205853618 0.239450513 3.760855557 -2.45490761 0.308212095 2.314979891 FBgn0053105 p24-2 p24-related-2 http://flybase.org/reports/FBgn0053105 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence model transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR009038 Golgi vesicle transport ; GO:0048193 | inferred from sequence model reproduction ; GO:0000003 | inferred from mutant phenotype regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from sequence model "CG33105, CG9443, p24-2, p24" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG33105 11-Aug-17 DroID_v2017_08 "Drer\tmed9, Drer\tmed4, Drer\si:ch211-255i20.3" "Scer\ERP6, Scer\ERP1, Scer\ERP5" "Cele\T08D2.1, Cele\Y60A3A.9" "Xtro\tmed4, Xtro\tmed9" "Mmus\Tmed9, Mmus\Tmed11, Mmus\Tmed4" "Hsap\TMED9, Hsap\TMED4" "partially lethal - majority die,viable,male semi-sterile" FBgn0263607 l(3)72Dp lethal (3) 72Dp http://flybase.org/reports/FBgn0263607 protein_coding_gene omega peptidase activity ; GO:0008242 | inferred from electronic annotation with InterPro:IPR015527 "glutamine metabolic process ; GO:0006541 | inferred from electronic annotation with InterPro:IPR011697, InterPro:IPR015527 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available "l(3)72Dp, CG32155, CG5082" "IPR011697:Peptidase C26, IPR015527:Peptidase C26, gamma-glutamyl hydrolase, IPR029062:Class I glutamine amidotransferase-like" CG32155 11-Aug-17 DroID_v2017_08 "Drer\zgc:171566, Drer\LOC553228, Drer\ggh" - "Cele\fbxb-118, Cele\fbxb-119" Xtro\ggh Mmus\Ggh Hsap\GGH FBgn0037074 CG7324 - http://flybase.org/reports/FBgn0037074 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 "CG7324, Q9VP46" "IPR000195:Rab-GTPase-TBC domain, IPR004182:GRAM domain, IPR002048:EF-hand domain, IPR011993:PH domain-like" CG7324 11-Aug-17 DroID_v2017_08 "Drer\tbc1d9, Drer\tbc1d8, Drer\tbc1d9b, Drer\sgsm3, Drer\tbc1d10ab, Drer\grtp1a, Drer\si:dkey-110k5.6" "Scer\MSB4, Scer\MSB3, Scer\MDR1" "Cele\tbc-9, Cele\tbc-10, Cele\tbc-6, Cele\tbc-18" "Xtro\grtp1, Xtro\tbc1d9, Xtro\tbc1d9b, Xtro\tbc1d8b, Xtro\tbc1d10a" "Mmus\Tbc1d8, Mmus\Sgsm3, Mmus\Grtp1, Mmus\Tbc1d9b, Mmus\Tbc1d10a, Mmus\Tbc1d9, Mmus\Tbc1d10b, Mmus\Tbc1d8b" "Hsap\TBC1D8B, Hsap\TBC1D9, Hsap\TBC1D10B, Hsap\TBC1D9B, Hsap\GRTP1, Hsap\TBC1D8, Hsap\SGSM3, Hsap\TBC1D10A" viable DRSC11820 E -0.085879976 -0.429447272 -0.593927563 1.651116823 0.796728645 -0.169658213 FBgn0037347 CG1427 - http://flybase.org/reports/FBgn0037347 protein_coding_gene "transferase activity, transferring selenium-containing groups ; GO:0016785 | inferred from electronic annotation with InterPro:IPR019872" selenocysteinyl-tRNA(Sec) biosynthetic process ; GO:0097056 | inferred from electronic annotation with InterPro:IPR019872 - "CG1427, SecS" "IPR015424:Pyridoxal phosphate-dependent transferase, IPR019872:O-phosphoseryl-tRNA(Sec) selenium transferase, IPR008829:SepSecS/SepCysS family, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1" CG1427 11-Aug-17 DroID_v2017_08 Drer\sepsecs - Cele\secs-1 Xtro\sepsecs Mmus\Sepsecs Hsap\SEPSECS "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0036082 CG12362 - http://flybase.org/reports/FBgn0036082 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with ari-1 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 zinc ion binding ; GO:0008270 | inferred from sequence model positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with ari-1 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000188395 "CG12362, AAN11912.1" "IPR001841:Zinc finger, RING-type, IPR002867:IBR domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR031127:E3 ubiquitin ligase RBR family" CG12362 11-Aug-17 DroID_v2017_08 "Drer\arih1, Drer\arih2, Drer\ankib1b, Drer\rbck1, Drer\si:ch211-278j3.3, Drer\rnf144aa, Drer\rnf144b, Drer\ankib1a, Drer\rnf217, Drer\rnf19b, Drer\rnf19a, Drer\arih1l, Drer\shrprbck1r, Drer\rnf144ab" Scer\HEL1 "Cele\C27A12.7, Cele\tag-349, Cele\C27A12.6, Cele\ari-1, Cele\T12E12.1" "Xtro\rnf144a, Xtro\arih2, Xtro\cul9, Xtro\rnf217, Xtro\rnf19a, Xtro\rnf144b" "Mmus\Ankib1, Mmus\Rbck1, Mmus\Rnf144a, Mmus\Rnf217, Mmus\Rnf19a, Mmus\Arih2, Mmus\Sharpin, Mmus\Rnf144b, Mmus\Cul7, Mmus\Rnf19b, Mmus\Arih1, Mmus\Cul9" "Hsap\CUL7, Hsap\RNF19B, Hsap\ARIH2, Hsap\RNF31, Hsap\ANKIB1, Hsap\RNF144A, Hsap\RBCK1, Hsap\RNF144B, Hsap\CUL9, Hsap\RNF217, Hsap\ARIH1, Hsap\RNF19A" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0261049 Vps45 Vacuolar protein sorting 45 http://flybase.org/reports/FBgn0261049 protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with Rbsn-5 SNARE binding ; GO:0000149 | inferred from physical interaction with Syx16, Syx13, Syx7 SNARE binding ; GO:0000149 | inferred from sequence or structural similarity" vesicle docking involved in exocytosis ; GO:0006904 | inferred from electronic annotation with InterPro:IPR001619 neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity endocytosis ; GO:0006897 | inferred from mutant phenotype synaptic vesicle priming ; GO:0016082 | non-traceable author statement endosomal vesicle fusion ; GO:0034058 | inferred from mutant phenotype plasma membrane to endosome transport ; GO:0048227 | inferred from mutant phenotype early endosome ; GO:0005769 | inferred from direct assay synaptic vesicle ; GO:0008021 | non-traceable author statement "MENE(3R)-C, Vps45, MENE (3R)-C, CG8228, VPS45, Vps45p, dVps45, DmVps45" IPR001619:Sec1-like protein CG8228 11-Aug-17 DroID_v2017_08 Drer\vps45 Scer\VPS45 Cele\vps-45 Xtro\vps45 Mmus\Vps45 Hsap\VPS45 "lethal - all die before end of larval stage,recessive,some die during larval stage,visible" "eye disc,somatic clone,posterior wing margin,wing vein,yolk granule | germline clone" FBgn0039160 CG5510 - http://flybase.org/reports/FBgn0039160 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005052 endomembrane system ; GO:0012505 | inferred from direct assay CG5510 "IPR005052:Legume-like lectin, IPR013320:Concanavalin A-like lectin/glucanase domain" CG5510 11-Aug-17 DroID_v2017_08 "Drer\lman2lb, Drer\lman2la, Drer\lman2" "Scer\EMP46, Scer\UIP5, Scer\EMP47" Cele\ile-2 "Xtro\lman2, Xtro\lman2l" "Mmus\Lman2l, Mmus\Lman2" "Hsap\LMAN2L, Hsap\LMAN2" DRSC15823 I 1.685934378 -0.150751742 -0.043910513 -0.188621639 -0.385889139 -0.757455793 FBgn0000455 Dip-C Dipeptidase C http://flybase.org/reports/FBgn0000455 FBgn0038040 protein_coding_gene manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR007865 dipeptidyl-peptidase activity ; GO:0008239 | inferred from direct assay proteolysis ; GO:0006508 | inferred from direct assay - "CG5663, Dip-C, dipC" "IPR000994:Peptidase M24, IPR001131:Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site, IPR007865:Aminopeptidase P, N-terminal, IPR029149:Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR028980:Creatinase/Aminopeptidase P, N-terminal" CG5663 11-Aug-17 DroID_v2017_08 "Drer\xpnpep3, Drer\pepd" "Scer\YFR006W, Scer\ICP55" "Cele\K12C11.1, Cele\pqn-59, Cele\R119.2" Xtro\pepd "Mmus\Pepd, Mmus\Xpnpep3" "Hsap\XPNPEP3, Hsap\PEPD" viable FBgn0039475 CG6277 - http://flybase.org/reports/FBgn0039475 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 neurogenesis ; GO:0022008 | inferred from mutant phenotype lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG6277, DmelL2" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6277 11-Aug-17 DroID_v2017_08 "Drer\pla1a, Drer\lipca, Drer\lipib, Drer\lpl, Drer\LOC100331214, Drer\lipia, Drer\LOC101884800, Drer\lipg" - - "Xtro\lipg, Xtro\lpl" "Mmus\Pnlip, Mmus\Lipc, Mmus\Lipi, Mmus\Pnliprp1, Mmus\Lpl, Mmus\Liph, Mmus\Pnliprp2, Mmus\Pla1a, Mmus\Lipg" "Hsap\PNLIPRP1, Hsap\LIPI, Hsap\LIPH, Hsap\LPL, Hsap\PNLIPRP2, Hsap\PNLIPRP3, Hsap\PLA1A, Hsap\PNLIP, Hsap\LIPC, Hsap\LIPG" "viable,lethal,neuroanatomy defective,visible" "ganglion mother cell,embryonic/larval neuroblast,trichogen cell" FBgn0015230 Glut3 Glucose transporter type 3 http://flybase.org/reports/FBgn0015230 - protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from sequence or structural similarity glucose binding ; GO:0005536 | inferred from sequence or structural similarity with UniProtKB:P11169 glucose transmembrane transporter activity ; GO:0005355 | inferred from sequence or structural similarity with UniProtKB:P11169 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose transmembrane transport ; GO:1904659 | inferred from sequence or structural similarity with UniProtKB:P11169 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with UniProtKB:P11169 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:P11169 "GLU, glut-l, CG3853, Glut3" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG3853 11-Aug-17 DroID_v2017_08 "Drer\slc2a10, Drer\slc2a12, Drer\slc2a8, Drer\LOC101882338, Drer\slc2a13b, Drer\slc2a6" "Scer\MAL11, Scer\VPS73, Scer\HXT3, Scer\GEX1, Scer\YDL199C, Scer\YBR241C, Scer\YMR279C, Scer\VBA2, Scer\AZR1, Scer\ENB1, Scer\HXT11, Scer\VBA5, Scer\ITR1, Scer\HXT10, Scer\VBA1, Scer\VBA4, Scer\GEX2, Scer\VBA3, Scer\HXT5, Scer\MPH3, Scer\SNF3, Scer\RGT2, Scer\HXT8, Scer\MPH2, Scer\YDR387C, Scer\HXT6, Scer\HXT9, Scer\HXT2, Scer\HXT13, Scer\HXT15, Scer\MAL31, Scer\HXT17, Scer\HXT7, Scer\HXT16, Scer\GAL2, Scer\SGE1, Scer\HXT1, Scer\ATR1, Scer\HXT14, Scer\YFL040W, Scer\HXT4, Scer\ITR2, Scer\STL1" "Cele\ZK829.9, Cele\slcf-2, Cele\C03B1.13, Cele\F14E5.1, Cele\K08F9.1, Cele\K08H10.6, Cele\C35A11.4, Cele\hmit-1.2, Cele\F13B12.2, Cele\Y39E4B.5, Cele\F48E3.2, Cele\Y37A1A.3, Cele\Y61A9LA.1" "Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a12" "Mmus\Slc2a12, Mmus\Slc2a6, Mmus\Slc2a8, Mmus\Slc2a13, Mmus\Slc2a10" "Hsap\SLC2A8, Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SLC2A12, Hsap\SLC2A10" viable DRSC16681 K 0.628305853 -0.380270276 0.950980011 -0.191236658 2.500965378 0.394396089 FBgn0020389 Papss PAPS synthetase http://flybase.org/reports/FBgn0020389 - protein_coding_gene "sulfate adenylyltransferase (ATP) activity ; GO:0004781 | inferred from electronic annotation with InterPro:IPR002650, InterPro:IPR024951 adenylylsulfate kinase activity ; GO:0004020 | inferred from electronic annotation with InterPro:IPR002891 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002891" "sulfate assimilation ; GO:0000103 | inferred from electronic annotation with InterPro:IPR002650, InterPro:IPR002891 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from direct assay "papss, PAPS, CG8363, DmPAPSS, Papss, Paps, PAPSS, paps, l(3)76BDn" "IPR015947:PUA-like domain, IPR024951:Sulphate adenylyltransferase catalytic domain, IPR002650:Sulphate adenylyltransferase, IPR002891:Adenylyl-sulfate kinase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR025980:ATP-sulfurylase PUA-like domain" CG8363 11-Aug-17 DroID_v2017_08 "Drer\papss1, Drer\papss2b, Drer\papss2a" "Scer\MET14, Scer\MET3" Cele\pps-1 "Xtro\papss2, Xtro\ncstn, Xtro\papss1" "Mmus\Papss1, Mmus\Papss2" "Hsap\PAPSS2, Hsap\PAPSS1" "lethal,recessive,chemical sensitive,dominant,visible,viable" "presumptive embryonic salivary gland,embryonic/first instar larval cuticle,germline clone,somatic clone,wing,posterior compartment" DRSC27101 K -0.575140183 0.043480878 -0.048483649 0.404755807 1.731135212 -0.967915749 FBgn0035936 Tsp66E Tetraspanin 66E http://flybase.org/reports/FBgn0035936 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG4999, Dm.Tsp66E, Tsp66E" "IPR018499:Tetraspanin/Peripherin, IPR018503:Tetraspanin, conserved site, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG4999 11-Aug-17 DroID_v2017_08 "Drer\cd82b, Drer\tspan35, Drer\cd81a, Drer\tspan9b, Drer\tspan34, Drer\cd82a, Drer\tspan2a, Drer\zgc:64051, Drer\tspan4a, Drer\zgc:171713, Drer\tspan18a, Drer\tspan9a, Drer\upk1a, Drer\tspan37, Drer\tspan18b, Drer\tspan4b" - "Cele\tsp-6, Cele\tsp-15, Cele\tsp-4, Cele\tsp-13, Cele\tsp-5, Cele\tsp-11, Cele\tsp-8, Cele\tsp-10, Cele\tsp-19" "Xtro\tspan2, Xtro\tspan18, Xtro\cd82, Xtro\tspan1, Xtro\cd37, Xtro\cd81" "Mmus\Upk1b, Mmus\Tspan9, Mmus\Tspan4, Mmus\Upk1a, Mmus\Tspan18, Mmus\Cd53, Mmus\Tspan8, Mmus\Cd37, Mmus\Cd82, Mmus\Cd81, Mmus\Tspan1, Mmus\Tspan2" "Hsap\TSPAN16, Hsap\TSPAN18, Hsap\CD53, Hsap\TSPAN1, Hsap\TSPAN8, Hsap\CD81, Hsap\CD82, Hsap\UPK1B, Hsap\CD37, Hsap\UPK1A, Hsap\CD63, Hsap\TSPAN4, Hsap\TSPAN9, Hsap\TSPAN2" "lethal,maternal effect,some die during embryonic stage,viable" "egg,maternal effect" FBgn0047178 CG32147 - http://flybase.org/reports/FBgn0047178 protein_coding_gene pyroglutamyl-peptidase activity ; GO:0016920 | inferred from electronic annotation with InterPro:IPR000816 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000600628 cytosol ; GO:0005829 | inferred from electronic annotation with InterPro:IPR000816 "BcDNA:RE07960, CG32147" "IPR000816:Peptidase C15, pyroglutamyl peptidase I, IPR016125:Peptidase C15, pyroglutamyl peptidase I-like" CG32147 11-Aug-17 DroID_v2017_08 "Drer\pgpep1, Drer\pgpep1l" - "Cele\F35F10.7, Cele\M04C9.3, Cele\F16H6.4, Cele\F35F10.6, Cele\M04C9.2, Cele\M04C9.1, Cele\W04E12.7, Cele\F16H6.7" "Xtro\pgpep1l, Xtro\pgpep1" "Mmus\Pgpep1l, Mmus\Pgpep1" "Hsap\PGPEP1, Hsap\PGPEP1L" viable FBgn0039204 CG6607 - http://flybase.org/reports/FBgn0039204 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab5 Rab protein signal transduction ; GO:0032482 | inferred by curator from GO:0017137 early endosome ; GO:0005769 | inferred from direct assay "CG6607, Ccdc128" "IPR019343:Uncharacterised domain KLRAQ/TTKRSYEDQ, N-terminal, IPR019348:Uncharacterised domain KLRAQ/TTKRSYEDQ, C-terminal" CG6607 11-Aug-17 DroID_v2017_08 "Drer\cep135, Drer\ppp1r21, Drer\zgc:85975" - "Cele\C18C4.5, Cele\F33E11.3" "Xtro\eea1, Xtro\ppp1r21, Xtro\fam184a" "Mmus\Golga5, Mmus\Optn, Mmus\Ppp1r21" Hsap\PPP1R21 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0029152 Mkrn1 Makorin 1 http://flybase.org/reports/FBgn0029152 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:7112 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:7112 cellular_component ; GO:0005575 | no biological data available "MKRN1, CG7184, Mkrn1" "IPR000571:Zinc finger, CCCH-type, IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR018957:Zinc finger, C3HC4 RING-type" CG7184 11-Aug-17 DroID_v2017_08 "Drer\rnf141, Drer\mkrn2, Drer\mkrn4, Drer\mkrn1" Scer\LEE1 Cele\Y55F3AM.6 "Xtro\mkrn1, Xtro\mkrn2, Xtro\rnf141, Xtro\mkrn3" "Mmus\Mkrn3, Mmus\Mkrn1, Mmus\Rnf141, Mmus\Mkrn2" "Hsap\RNF141, Hsap\MKRN2, Hsap\MKRN1, Hsap\MKRN3" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0025865 Cortactin Cortactin http://flybase.org/reports/FBgn0025865 - protein_coding_gene proline-rich region binding ; GO:0070064 | inferred from genetic interaction with mim female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of receptor-mediated endocytosis ; GO:0048260 | inferred from genetic interaction with mim sperm individualization complex ; GO:0070864 | inferred from direct assay actin cap ; GO:0030478 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with mim plasma membrane ; GO:0005886 | inferred from direct assay "CG3637, Cortactin, cortactin, cttn" "IPR001452:SH3 domain, IPR003134:Hs1/Cortactin" CG3637 11-Aug-17 DroID_v2017_08 "Drer\hcls1, Drer\cttn" Scer\ABP1 - Xtro\cttn "Mmus\Cttn, Mmus\Hcls1" "Hsap\CTTN, Hsap\HCLS1" embryonic stage -- adult stage "viable,fertile,female fertile,reduced" "nurse cell ring canal,egg,nurse follicle cell,border follicle cell,cell autonomous,somatic clone,actin filament | ectopic" FBgn0031881 MME1 Mitochondrial Magnesium Exporter 1 http://flybase.org/reports/FBgn0031881 protein_coding_gene carnitine:acyl carnitine antiporter activity ; GO:0005476 | inferred from biological aspect of ancestor with PANTHER:PTN001183376 carnitine transmembrane transporter activity ; GO:0015226 | inferred from biological aspect of ancestor with PANTHER:PTN001183376 carnitine:acyl carnitine antiporter activity ; GO:0005476 | inferred from sequence or structural similarity with UniProtKB:O43772 magnesium ion transmembrane transporter activity ; GO:0015095 | inferred from direct assay acyl carnitine transport ; GO:0006844 | inferred from sequence or structural similarity with UniProtKB:O43772 mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:O43772 carnitine transport ; GO:0015879 | inferred from sequence or structural similarity with UniProtKB:O43772 magnesium ion export from mitochondrion ; GO:1990616 | inferred from direct assay inferred from mutant phenotype carnitine transport ; GO:0015879 | inferred from biological aspect of ancestor with PANTHER:PTN001183376 magnesium ion transmembrane transport ; GO:1903830 | inferred from direct assay cellular magnesium ion homeostasis ; GO:0010961 | inferred from direct assay inferred from mutant phenotype mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:O43772 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001183376 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG3476, dMme1, MME1" "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG3476 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-150i13.2, Drer\slc25a15b, Drer\slc25a20, Drer\slc25a48, Drer\slc25a47a, Drer\slc25a45, Drer\slc25a15a, Drer\slc25a47b, Drer\LOC100329459" "Scer\YMC2, Scer\YMC1, Scer\CRC1" "Cele\slc-25A29, Cele\R07B7.10, Cele\T10F2.2, Cele\dif-1" "Xtro\slc25a48, Xtro\slc25a29, Xtro\slc25a45, Xtro\slc25a15, Xtro\slc25a20, Xtro\slc25a20.2, Xtro\slc25a47" "Mmus\Slc25a47, Mmus\Slc25a15, Mmus\Slc25a29, Mmus\Slc25a45, Mmus\Slc25a2, Mmus\Slc25a48, Mmus\Slc25a20" "Hsap\SLC25A48, Hsap\SLC25A47, Hsap\SLC25A20, Hsap\SLC25A2, Hsap\SLC25A29, Hsap\SLC25A15, Hsap\SLC25A45" viable FBgn0011762 DNApol-alpha50 DNA polymerase alpha 50kD http://flybase.org/reports/FBgn0011762 FBgn0044611 protein_coding_gene DNA primase activity ; GO:0003896 | inferred from biological aspect of ancestor with PANTHER:PTN000056764 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000056764 DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity "DNA replication ; GO:0006260 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA replication, synthesis of RNA primer ; GO:0006269 | inferred from sequence or structural similarity DNA replication, synthesis of RNA primer ; GO:0006269 | inferred from biological aspect of ancestor with PANTHER:PTN000056764" alpha DNA polymerase:primase complex ; GO:0005658 | inferred from sequence or structural similarity alpha DNA polymerase:primase complex ; GO:0005658 | inferred from direct assay "Dmpol alpha, DNApolalpha50, CG7108, pol alpha, DNA polalpha, polalpha50, Dpri50, polalpha, PRI1, Polalpha, POLA, DNApolalpha, DNApol-alpha, DNApol-alpha50, anon-WO0140519.257, Pol, dnapol alpha 50, Polalpha 50kDa, DNApolalpha-50" "IPR002755:DNA primase, small subunit, IPR014052:DNA primase, small subunit, eukaryotic/archaeal" CG7108 11-Aug-17 DroID_v2017_08 Drer\prim1 Scer\PRI1 "Cele\T24C4.5, Cele\pri-1" Xtro\prim1 Mmus\Prim1 Hsap\PRIM1 "lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,eye" FBgn0266053 Patr-1 Protein associated with topo II related - 1 http://flybase.org/reports/FBgn0266053 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000489218 deadenylation-dependent decapping of nuclear-transcribed mRNA ; GO:0000290 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype cytoplasmic mRNA processing body assembly ; GO:0033962 | inferred from mutant phenotype cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "HPat, hpat, patr-1, Patr-1, LD27979, BcDNA:LD27979, anon-WO0118547.282, CG5208, l(3)06442, Part-1" - CG5208 11-Aug-17 DroID_v2017_08 "Drer\patl1, Drer\si:ch211-103b1.2" Scer\PAT1 Cele\patr-1 "Xtro\patl2, Xtro\patl1" "Mmus\Patl1, Mmus\Patl2" "Hsap\PATL2, Hsap\PATL1" DRSC14159 K -0.153652138 -0.920681032 -0.963285195 0.158747694 1.513970493 1.246982516 FBgn0034350 CG5189 - http://flybase.org/reports/FBgn0034350 protein_coding_gene guanyl-nucleotide exchange factor activity ; GO:0005085 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q9Y2Q5 protein complex scaffold ; GO:0032947 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q9Y2Q5 cellular response to amino acid stimulus ; GO:0071230 | inferred from sequence or structural similarity with UniProtKB:Q9Y2Q5 positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype cellular protein localization ; GO:0034613 | inferred from sequence or structural similarity with UniProtKB:Q9Y2Q5 cell growth ; GO:0016049 | inferred from sequence or structural similarity with UniProtKB:Q9Y2Q5 cellular response to amino acid stimulus ; GO:0071230 | inferred from mutant phenotype Ragulator complex ; GO:0071986 | inferred from sequence or structural similarity with UniProtKB:Q9Y2Q5 "CG5189, p14, dp14" IPR004942:Roadblock/LAMTOR2 domain CG5189 11-Aug-17 DroID_v2017_08 "Drer\lamtor2, Drer\zgc:101679" - Cele\lmtr-2 Xtro\lamtor2 Mmus\Lamtor2 Hsap\LAMTOR2 "viable,visible" trichogen cell FBgn0033021 CG10417 - http://flybase.org/reports/FBgn0033021 protein_coding_gene cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR000222 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000000329 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000000329 protein dephosphorylation ; GO:0006470 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000329 "CG10417, PP2Cg" "IPR000222:PPM-type phosphatase, divalent cation binding, IPR001932:PPM-type phosphatase domain, IPR015655:Protein phosphatase 2C family" CG10417 11-Aug-17 DroID_v2017_08 "Drer\ppm1aa, Drer\ppm1ab, Drer\tab1, Drer\ppm1bb, Drer\ppm1g, Drer\ppm1ba" "Scer\PTC2, Scer\PTC3, Scer\PTC4" "Cele\ppm-2, Cele\ppm-1, Cele\F42G9.1, Cele\tap-1" "Xtro\tab1, Xtro\ppm1g" "Mmus\Ppm1g, Mmus\Tab1, Mmus\Ppm1a, Mmus\Ppm1b" "Hsap\TAB1, Hsap\PPM1A, Hsap\PPM1G, Hsap\PPM1B" DRSC04846 K 1.158956107 0.438035251 0.204756774 0.52779196 -0.037511391 1.522519248 FBgn0022355 Tsf1 Transferrin 1 http://flybase.org/reports/FBgn0022355 FBgn0025536 protein_coding_gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype response to fungus ; GO:0009620 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "Transferrin 1, Tsf1, 143958_at, CG6186, TSF1, Tf, Trf, anon-EST:Posey265, tsf1, lincRNA.S9601" "IPR018195:Transferrin family, iron binding site, IPR001156:Transferrin-like domain" CG6186 11-Aug-17 DroID_v2017_08 "Drer\otomp, Drer\tfa, Drer\zgc:172271, Drer\mfi2" - - "Xtro\depdc5, Xtro\tf, Xtro\mfi2" "Mmus\Mfi2, Mmus\Trf, Mmus\1300017J02Rik, Mmus\Ltf" "Hsap\MELTF, Hsap\LTF, Hsap\TF" "viable,fertile" DRSC20296 K -0.344039503 -0.145976112 0.076732204 0.395162191 -2.085982212 0.332887738 FBgn0034538 CG16799 - http://flybase.org/reports/FBgn0034538 protein_coding_gene - - - CG16799 "IPR001916:Glycoside hydrolase, family 22, IPR023346:Lysozyme-like domain, IPR019799:Glycoside hydrolase, family 22, conserved site" CG16799 11-Aug-17 DroID_v2017_08 "Drer\lyz, Drer\LOC100334363, Drer\LOC100536671" - - Xtro\MGC89221 "Mmus\Lyzl6, Mmus\Spaca4, Mmus\Lyz2, Mmus\Spaca7, Mmus\1700016D06Rik, Mmus\9530003J23Rik, Mmus\Lalba, Mmus\Spaca1, Mmus\Lyzl1, Mmus\Lyzl4, Mmus\Lyz1, Mmus\Spaca5, Mmus\Spaca3" "Hsap\LYZL6, Hsap\LYZ, Hsap\SPACA5B, Hsap\SPACA4, Hsap\SPACA5, Hsap\LYZL1, Hsap\LYZL2, Hsap\SPACA3, Hsap\SPACA1, Hsap\LALBA, Hsap\LYZL4, Hsap\SPACA7" "viable,fertile" FBgn0032297 CG17124 - http://flybase.org/reports/FBgn0032297 protein_coding_gene - regulation of phosphorylation ; GO:0042325 | inferred from electronic annotation with InterPro:IPR008025 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR008025 "anon-WO0118547.153, CG17124" IPR008025:PKC-activated phosphatase-1 inhibitor CG17124 11-Aug-17 DroID_v2017_08 "Drer\ppp1r14aa, Drer\zgc:162989, Drer\ppp1r14c, Drer\ppp1r14bb, Drer\ppp1r14ba, Drer\ppp1r14ab" - Cele\F55C10.5 "Xtro\ppp1r14c, Xtro\ppp1r14a, Xtro\ppp1r14b" "Mmus\Ppp1r14c, Mmus\Ppp1r14b, Mmus\Ppp1r14d, Mmus\Ppp1r14a, Mmus\4933415F23Rik" "Hsap\PPP1R14A, Hsap\PPP1R14C, Hsap\PPP1R14B, Hsap\PPP1R14D" "viable,fertile" FBgn0041789 Pax Paxillin http://flybase.org/reports/FBgn0041789 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 cell-matrix adhesion ; GO:0007160 | inferred from electronic annotation with InterPro:IPR001904 dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity wing disc development ; GO:0035220 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from genetic interaction with Rac1 inferred from genetic interaction with Rho1 leg disc development ; GO:0035218 | inferred from mutant phenotype regulation of myoblast fusion ; GO:1901739 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from genetic interaction with Atg1 cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR001904 focal adhesion ; GO:0005925 | inferred from direct assay muscle tendon junction ; GO:0005927 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from sequence or structural similarity "Pax, CG31794, DPxn, DPaxillin, DPxn37, PDLP, CG18576, Dpax, CT42454, CT40481, CG18061, pax, DpaxA, dPax, Paxillin" "IPR001781:Zinc finger, LIM-type, IPR001904:Paxillin" CG31794 11-Aug-17 DroID_v2017_08 "Drer\pxna, Drer\pdlim4, Drer\pdlim3a, Drer\pxnb, Drer\si:rp71-15d4.1, Drer\pdlim5b, Drer\pdlim2, Drer\pdlim1, Drer\pdlim5a, Drer\pdlim3b" "Scer\LRG1, Scer\PXL1" "Cele\C34B2.4, Cele\pxl-1, Cele\Y1A5A.1, Cele\Y65B4A.7, Cele\C26C6.6, Cele\alp-1, Cele\F33D11.1" "Xtro\pdlim4, Xtro\pdlim1, Xtro\pdlim7, Xtro\pdlim3, Xtro\pdlim5, Xtro\pxn, Xtro\tgfb1i1" "Mmus\Pdlim7, Mmus\Pdlim5, Mmus\Lpxn, Mmus\Pdlim3, Mmus\Arhgap28, Mmus\Pdlim4, Mmus\Pdlim1, Mmus\Tgfb1i1, Mmus\Crip2, Mmus\Pdlim2, Mmus\Pxn, Mmus\Ldb3" "Hsap\PXN, Hsap\PDLIM3, Hsap\LPXN, Hsap\PDLIM4, Hsap\PDLIM1, Hsap\ARHGAP28, Hsap\LDB3, Hsap\TGFB1I1, Hsap\PDLIM2, Hsap\PDLIM7, Hsap\LIMS4, Hsap\PDLIM5" larval stage | third instar muscle fiber | vicinity of muscle attachment site

"viable,fertile,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of pupal stage,lethal,heat sensitive,visible,partially lethal - majority live" "egg chamber,conditional,dorsal appendage,autophagic vacuolepr-A16),fat body,embryonic myoblast,embryonic/larval epidermis,heat sensitive,wing vein,ectopic,wing,leg,ventral transverse muscle 1,dorsal transverse muscle,dorsal acute muscle 1,nucleus | supernumeraryeve.eme,ventral acute muscle 2" FBgn0001296 kar karmoisin http://flybase.org/reports/FBgn0001296 FBgn0038077 protein_coding_gene thyroid hormone transmembrane transporter activity ; GO:0015349 | inferred from electronic annotation with InterPro:IPR030761 thyroid hormone transport ; GO:0070327 | inferred from electronic annotation with InterPro:IPR030761 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR030761 "CG12286, kar" "IPR020846:Major facilitator superfamily domain, IPR011701:Major facilitator superfamily, IPR030761:Monocarboxylate transporter 8" CG12286 11-Aug-17 DroID_v2017_08 "Drer\slc16a1a, Drer\slc16a5b, Drer\slc16a1b, Drer\si:ch211-234h8.7, Drer\slc16a7, Drer\slc16a3, Drer\slc16a10, Drer\slc16a2, Drer\slc16a5a, Drer\slc16a8, Drer\zgc:165507" "Scer\ATG22, Scer\MCH2, Scer\MCH5, Scer\MCH4, Scer\ESBP6" "Cele\gem-1, Cele\cat-1, Cele\mct-2, Cele\mct-1, Cele\mct-3" "Xtro\slc16a2, Xtro\slc16a10" "Mmus\Slc16a5, Mmus\Slc16a11, Mmus\Slc16a10, Mmus\Slc16a1, Mmus\Slc16a3, Mmus\Slc16a7, Mmus\Slc16a8, Mmus\Slc16a2" "Hsap\SLC16A7, Hsap\SLC16A8, Hsap\SLC16A11, Hsap\SLC16A10, Hsap\SLC16A3, Hsap\SLC16A1, Hsap\SLC16A2, Hsap\SLC16A5" "viable,fertile,eye color defective,recessive,visible" "pigment cell,ocellus,ocellus pigment granule,Malpighian tubule" FBgn0004701 l(2)56Fb lethal (2) 56Fb http://flybase.org/reports/FBgn0004701 - gene - - - "l(2)56F, l(2)12, l(2)56Fb" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0027660 blot bloated tubules http://flybase.org/reports/FBgn0027660 - protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from electronic annotation with InterPro:IPR000175 morphogenesis of an epithelium ; GO:0002009 | traceable author statement transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence model integral component of membrane ; GO:0016021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 "l(3)1658, CG3897, blot, DmBLOT" IPR000175:Sodium:neurotransmitter symporter CG3897 11-Aug-17 DroID_v2017_08 "Drer\zgc:174946, Drer\slc6a13l, Drer\slc6a13, Drer\slc6a11a, Drer\si:ch211-132b12.6, Drer\slc6a8, Drer\si:ch211-132b12.1, Drer\si:ch211-132b12.2, Drer\si:ch211-132b12.3, Drer\si:ch211-117c9.5" - "Cele\snf-11, Cele\Y43D4A.1, Cele\snf-3, Cele\snf-12" Xtro\slc6a13 "Mmus\Slc6a8, Mmus\Slc6a20b" Hsap\SLC6A8 "viable,fertile,lethal,female fertile,germline clone,reduced,non-rescuable maternal effect,recessive,lethal - all die before end of larval stage,some die during larval stage" "denticle,Malpighian tubule,blastoderm embryo,germline clone,pole cell" FBgn0023509 mip130 Myb-interacting protein 130 http://flybase.org/reports/FBgn0023509 - protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR010561 eggshell chorion gene amplification ; GO:0007307 | inferred by curator from GO:0031523 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype transcriptional repressor complex ; GO:0017053 | inferred from electronic annotation with InterPro:IPR010561 nucleus ; GO:0005634 | inferred from sequence or structural similarity Myb complex ; GO:0031523 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Mip130/TWIT, TWIT, Mip130, twit, EG:86E4.4, CG3480, 86E4.4, mip130, Twit, Mip130/Twt" "IPR010561:Protein LIN-9/Protein ALWAYS EARLY, IPR033471:DIRP domain" CG3480 11-Aug-17 DroID_v2017_08 Drer\lin9 - Cele\lin-9 Xtro\lin9 Mmus\Lin9 Hsap\LIN9 "viable,small body,female sterile,female semi-sterile,partially lethal - majority live" chorion DRSC18575 IE 4.627075262 -0.706870959 3.704869709 -2.205621722 0.408451166 -0.523679245 FBgn0033063 CG14589 - http://flybase.org/reports/FBgn0033063 protein_coding_gene - - - CG14589 - CG14589 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027594 drpr draper http://flybase.org/reports/FBgn0027594 FBgn0035261 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7JUY7 phosphatidylserine binding ; GO:0001786 | inferred from direct assay "cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype positive regulation of phagocytosis, engulfment ; GO:0060100 | inferred from mutant phenotype apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype response to axon injury ; GO:0048678 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap neuron remodeling ; GO:0016322 | inferred from mutant phenotype phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype phagocytosis ; GO:0006909 | traceable author statement regulation of neuromuscular junction development ; GO:1904396 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype engulfment of apoptotic cell ; GO:0043652 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay axon ; GO:0030424 | inferred from mutant phenotype intrinsic component of membrane ; GO:0031224 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay postsynapse ; GO:0098794 | inferred from mutant phenotype "BcDNA:GH03529, CG18172, CT41022, CT6730, CG2086, drpr, draper, Drpr" "IPR000742:EGF-like domain, IPR002049:Laminin EGF domain, IPR011489:EMI domain, IPR013032:EGF-like, conserved site" CG2086 11-Aug-17 DroID_v2017_08 "Drer\flt1, Drer\pdgfrl, Drer\dkk1a, Drer\pdgfra, Drer\flt3, Drer\fgfrl1b, Drer\megf6a, Drer\tie1, Drer\fgfr4, Drer\megf11, Drer\tmeff1b, Drer\pear1, Drer\esm1, Drer\kdr, Drer\csf1rb, Drer\LOC569566, Drer\fgfr3, Drer\megf10, Drer\si:ch73-206d17.1, Drer\si:dkey-14o18.6, Drer\fgfr1a, Drer\tmeff1a, Drer\fgfrl1a, Drer\fgfr2, Drer\ret, Drer\tek, Drer\kitb, Drer\ccbe1, Drer\zgc:158328, Drer\kdrl, Drer\megf6b, Drer\tnfaip6, Drer\styk1, Drer\kita, Drer\csf1ra, Drer\scarf1, Drer\dkk2, Drer\flt4, Drer\si:ch211-167j9.5, Drer\tmeff2a, Drer\pdgfrb" - "Cele\arg-1, Cele\Y64G10A.7, Cele\ced-1" "Xtro\flt1, Xtro\flt4, Xtro\pdgfrl, Xtro\pear1, Xtro\kdr, Xtro\ret, Xtro\csf1r, Xtro\pdgfrl.2, Xtro\megf10, Xtro\tie1, Xtro\stab2, Xtro\fgfrl1, Xtro\megf11, Xtro\tek, Xtro\fgfr3, Xtro\fgfr2, Xtro\fgfr1, Xtro\fgfr4, Xtro\pdgfra, Xtro\styk1, Xtro\tnfaip6" "Mmus\Megf10, Mmus\Fgfrl1, Mmus\Scarf1, Mmus\Tnfaip6, Mmus\Csf1r, Mmus\Kdr, Mmus\Stab1, Mmus\Megf11, Mmus\Flt4, Mmus\Tek, Mmus\Egfem1, Mmus\Megf6, Mmus\Ret, Mmus\Pear1, Mmus\Kit, Mmus\Tie1, Mmus\Pdgfra, Mmus\Flt3, Mmus\Styk1, Mmus\Flt1, Mmus\Fgfr4, Mmus\Fgfr1, Mmus\Tmeff2, Mmus\Fgfr3, Mmus\Dkk3, Mmus\Dkk2, Mmus\Pdgfrl, Mmus\Pdgfrb, Mmus\Fgfr2, Mmus\Esm1, Mmus\Tmeff1" "Hsap\MEGF10, Hsap\KIT, Hsap\TMEFF2, Hsap\FLT3, Hsap\FGFR4, Hsap\PEAR1, Hsap\FLT1, Hsap\FGFR1, Hsap\SCARF1, Hsap\FLT4, Hsap\STYK1, Hsap\RET, Hsap\DKK2, Hsap\FGFRL1, Hsap\KDR, Hsap\PDGFRB, Hsap\TIE1, Hsap\SCARF2, Hsap\PDGFRL, Hsap\FGFR2, Hsap\CRB2, Hsap\CSF1R, Hsap\MEGF11, Hsap\TEK, Hsap\TNFAIP6, Hsap\PDGFRA, Hsap\MEGF6, Hsap\MSANTD3-TMEFF1, Hsap\FGFR3" "neuroanatomy defective,cell death defective,nutrition conditional,conditional,uncoordinated,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,viable,immune response defective,germline clone,increased cell death" "adult olfactory receptor neuron,embryonic/larval salivary gland,lysosomefkh.PH,ensheathing neuropil associated glial cell,egg chamber,nutrition conditional,follicle cell,reticular neuropil associated glial cell,gamma Kenyon cell,wing vein L1,conditional,glial cell,dendrite,embryonic hemocyte,dorsal multidendritic neuron ddaC,adult mushroom body,germline clone,dorsal multidendritic neuron ddaC | pupal stage,nurse cell" FBgn0013643 mfs(2)1 mfs(2)1 http://flybase.net/reports/FBgn0013643.html gene 11-Aug-17 DroID_v2017_08 "male sterile,female sterile" FBgn0015791 Rab14 Rab14 http://flybase.org/reports/FBgn0015791 "FBgn0014431, FBgn0027898" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225, InterPro:IPR030702 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" endocytic recycling ; GO:0032456 | inferred from electronic annotation with InterPro:IPR030702 Golgi to endosome transport ; GO:0006895 | inferred from electronic annotation with InterPro:IPR030702 regulation of endocytosis ; GO:0030100 | inferred from biological aspect of ancestor with PANTHER:PTN001530980 phagolysosome assembly ; GO:0001845 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 phagosome acidification ; GO:0090383 | inferred from mutant phenotype phagocytic vesicle ; GO:0045335 | inferred from electronic annotation with InterPro:IPR030702 recycling endosome ; GO:0055037 | inferred from electronic annotation with InterPro:IPR030702 trans-Golgi network ; GO:0005802 | inferred from electronic annotation with InterPro:IPR030702 late endosome ; GO:0005770 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 early endosome ; GO:0005769 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "AAF53390, DmRab14, rab14, CG4212, ESTS:57H4T, BG:DS01068.7, 57H4T, DRab14, DRAB14, anon-sts33, Rab-r14, Rab14, O18336" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR030702:Ras-related protein Rab14, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4212 11-Aug-17 DroID_v2017_08 "Drer\rab14, Drer\rab14l" "Scer\YPT31, Scer\YPT32" Cele\rab-14 Xtro\rab14 Mmus\Rab14 Hsap\RAB14 "fertile,immune response defective,viable,wild-type" "phagocytic vesicle,hemocyte,phagocytic vesicleHml.‘î,hemocyte | adult stage" FBgn0016794 dos daughter of sevenless http://flybase.org/reports/FBgn0016794 - protein_coding_gene SH2 domain binding ; GO:0042169 | inferred from physical interaction with csw SH3/SH2 adaptor activity ; GO:0005070 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q08012 "regulation of Ras protein signal transduction ; GO:0046578 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | non-traceable author statement sevenless signaling pathway ; GO:0045500 | traceable author statement antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement wing disc development ; GO:0035220 | inferred from mutant phenotype photoreceptor cell development ; GO:0042461 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay "141511_at, Dos, DOS, Su(sev)3A, E(csw)3A, Su(sev[S11])3A, E(csw[CS])3A, CG1044, dos, EC3-4, Gab-1" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG1044 11-Aug-17 DroID_v2017_08 "Drer\zgc:153920, Drer\plekhs1, Drer\zgc:158404, Drer\si:ch211-28p3.3, Drer\gab1, Drer\gab2, Drer\si:ch73-92i20.1" - Cele\soc-1 "Xtro\gab2, Xtro\gab1, Xtro\gab3" "Mmus\Gab2, Mmus\Plekhs1, Mmus\Gab1, Mmus\Gab3" "Hsap\GAB2, Hsap\PLEKHS1, Hsap\GAB4, Hsap\GAB3, Hsap\GAB1" larval stage | third instar " eye-antennal disc

, morphogenetic furrow | posterior to

, morphogenetic furrow

" "viable,fertile,lethal,recessive,wild-type,partially lethal - majority die,some die during larval stage" "anterior crossvein,eye,photoreceptor cell R7,wing vein,wing vein L4,eye photoreceptor cell,filzkorper,germline clone,embryonic abdominal segment 8,embryonic head,Malpighian tubule,cephalopharyngeal skeleton,ommatidium,cone cell,somatic clone,A1-7 ventral acute muscle 2,precursor,photoreceptor" DRSC07992 IEK -2.12983894 -5.068627078 -2.202789088 -3.346431818 -6.72843955 -6.15132667 FBgn0034666 CG9294 - http://flybase.org/reports/FBgn0034666 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP20, CG9294" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG9294 11-Aug-17 DroID_v2017_08 "Drer\zgc:112302, Drer\LOC100331291, Drer\zgc:171592, Drer\zgc:112368, Drer\zgc:123217, Drer\ela3l, Drer\ctrl, Drer\tmprss13a, Drer\f2, Drer\zgc:154142, Drer\tmprss13b, Drer\zgc:92041, Drer\zgc:163079, Drer\zgc:92511, Drer\zgc:112285, Drer\LOC562139, Drer\si:dkey-57c15.4, Drer\ela2l, Drer\zgc:92745, Drer\ctrb1, Drer\zgc:112160, Drer\ela2, Drer\si:dkey-238d18.3" - "Cele\try-3, Cele\svh-1, Cele\try-1" "Xtro\prss29, Xtro\ctrb1, Xtro\cela3a, Xtro\LOC100135144, Xtro\ctrb2, Xtro\cela2a" "Mmus\Tmprss11a, Mmus\Tmprss11c, Mmus\Prss57, Mmus\Ctrb1, Mmus\Ctrl, Mmus\Prss40, Mmus\Tmprss11b, Mmus\Cela1, Mmus\Prss39, Mmus\Tmprss11g, Mmus\Tmprss11d, Mmus\Tmprss6, Mmus\Prss45, Mmus\Cela3a, Mmus\Cela2a, Mmus\Tmprss11f, Mmus\Ctrc, Mmus\Cela3b, Mmus\Tmprss11e" "Hsap\TMPRSS11E, Hsap\TMPRSS11D, Hsap\CELA3B, Hsap\CELA2B, Hsap\TMPRSS11B, Hsap\TMPRSS6, Hsap\CTRL, Hsap\PRSS57, Hsap\HPN, Hsap\PRSS45, Hsap\CTRC, Hsap\CTRB1, Hsap\CELA3A, Hsap\CELA1, Hsap\TMPRSS5, Hsap\CTRB2, Hsap\CELA2A, Hsap\TMPRSS3, Hsap\TMPRSS2" viable DRSC04537 I -0.037579649 1.975164906 0.259679419 0.270211738 -0.78941162 0.796179081 FBgn0025360 Optix Optix http://flybase.org/reports/FBgn0025360 "FBgn0027365, FBgn0033251, FBgn0045871" protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype compound eye development ; GO:0048749 | non-traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype progression of morphogenetic furrow involved in compound eye morphogenesis ; GO:0007458 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from expression pattern - "optix, opt, CG18455, D-Six3, Dsix3, Six3, anon-WO0153538.79, Optix, opx, OPTIX, six3" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR031701:Homeobox protein SIX1, N-terminal SD domain" CG18455 11-Aug-17 DroID_v2017_08 "Drer\six4b, Drer\six1b, Drer\six5, Drer\six1a, Drer\six6b, Drer\six2b, Drer\six3a, Drer\six3b, Drer\six2a, Drer\six9, Drer\six6a, Drer\six7" - "Cele\ceh-33, Cele\ceh-32" "Xtro\six1, Xtro\six3, Xtro\six2, Xtro\six4, Xtro\six6" "Mmus\Six1, Mmus\Six6, Mmus\Six3, Mmus\Six4, Mmus\Six2, Mmus\Six5" "Hsap\SIX6, Hsap\SIX1, Hsap\SIX3, Hsap\SIX2, Hsap\SIX4, Hsap\SIX5" " embryonic stage , embryonic stage | stage 12,13 , larval stage | third instar , embryonic stage | stage 12 , embryonic stage | stage 5 , embryonic stage | stage 6 , embryonic stage | early " " terminal organ

, head sensillum

, labral segment

, embryonic maxillary segment

, frontal ganglion

, embryonic stomatogastric nervous system

, eye-antennal disc

, ectoderm | dorsal

, dorsal pouch

, organism | 80-90% egg length

, clypeo-labral disc

, stomodeum

, labial organ

, supraesophageal ganglion | presumptive | dorsal to

, larval labral segment sense organ

, embryonic supraesophageal neuromere

, procephalic neurogenic region

, gonad

,

dorsal & anterior , organism | 80-100% egg length

, embryonic labial segment

" "lethal,lethal - all die during larval stage,recessive,visible,somatic clone,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "eye,somatic clone,eye disc,ectopic,antenna,wing,haltere,adult head,eye photoreceptor cell,dorsal multidendritic neuron ddaC,ventral multidendritic neuron vdaB,ommatidium,eye disc & neuroney.PH,anterior,medial,interocellar bristle,ocellus" FBgn0035348 CG16758 - http://flybase.org/reports/FBgn0035348 protein_coding_gene "purine-nucleoside phosphorylase activity ; GO:0004731 | inferred from electronic annotation with InterPro:IPR011268, InterPro:IPR011270" nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 - "c62E-15, CG16760, CG16758" "IPR011268:Purine nucleoside phosphorylase, IPR011270:Purine nucleoside phosphorylase I, inosine/guanosine-specific, IPR000845:Nucleoside phosphorylase domain" CG16758 11-Aug-17 DroID_v2017_08 "Drer\pnp6, Drer\pnp5a, Drer\pnp4b, Drer\pnp5b, Drer\pnp4a" Scer\PNP1 Cele\K02D7.1 Xtro\pnp "Mmus\Pnp2, Mmus\Pnp" Hsap\PNP "viable,body color defective" mesothoracic tergum FBgn0010246 Myo61F Myosin 61F http://flybase.org/reports/FBgn0010246 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609 motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR010926 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microvillus organization ; GO:0032528 | inferred from mutant phenotype determination of digestive tract left/right asymmetry ; GO:0071907 | NOT inferred from mutant phenotype determination of left/right symmetry ; GO:0007368 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype "myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR010926 brush border ; GO:0005903 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay myosin complex ; GO:0016459 | inferred from sequence or structural similarity filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay" "MIB, Myo-IB, Dm IB, DmIB, MYOIB, CG9155, Myo1B, MYO61F, IB, DroMIB, Myo61F, myo61f, myo61F, MyoIC, Mhc2, myoIC, MyoIB" "IPR000048:IQ motif, EF-hand binding site, IPR001609:Myosin head, motor domain, IPR010926:Class I myosin tail homology domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9155 11-Aug-17 DroID_v2017_08 "Drer\si, Drer\LOC556989, Drer\myo1b, Drer\myo1hb, Drer\myo1ca, Drer\myo1eb, Drer\myo1ha, Drer\myo1f, Drer\myo1cb, Drer\si:ch211-94l19.4, Drer\myo1ea, Drer\si:dkeyp-92c9.3" "Scer\MYO3, Scer\MYO5" "Cele\hum-5, Cele\hum-1, Cele\hum-4" "Xtro\myo1a, Xtro\myo1d, Xtro\myo1e.2, Xtro\myo1f, Xtro\myo1c, Xtro\myo1h, Xtro\myo1e.1" "Mmus\Myo1b, Mmus\Myo1h, Mmus\Myo1c, Mmus\Myo1f, Mmus\Myo1a, Mmus\Myo1e, Mmus\Myo1d, Mmus\Myo1g" "Hsap\MYO1H, Hsap\MYO1A, Hsap\MYO1D, Hsap\MYO1F, Hsap\MYO1C, Hsap\MYO1E, Hsap\MYO1G, Hsap\MYO1B" embryonic stage -- adult stage " embryonic stage | late , oogenesis stage , embryonic stage -- adult stage , adult stage , embryonic stage " " gastric caecum

, posterior embryonic/larval midgut

, egg chamber

, mid embryonic/larval midgut

, centripetally migrating follicle cell

, embryonic/larval hindgut

, alimentary canal

, anterior embryonic/larval midgut

, embryonic/larval digestive system

, follicle cell

" "increased cell death,viable,axis specification defective" "embryonic/larval midgut primordium,embryonic hindgut,male genitalia,embryonic/larval midgut,enterocyte,brush border,microvillus" FBgn0052523 CG32523 - http://flybase.org/reports/FBgn0052523 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG1497, SP50, CG32523" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site" CG32523 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.5, Drer\ovch1, Drer\LOC100004427, Drer\LOC558805, Drer\si:ch211-165b19.9, Drer\zgc:92313, Drer\si:dkey-21e2.3, Drer\gzm3, Drer\si:dkey-21e2.16, Drer\zgc:163079, Drer\gzmk, Drer\zgc:165423, Drer\si:dkeyp-93a5.3, Drer\si:ch211-165b19.8, Drer\si:dkey-16l2.17, Drer\gzma, Drer\cfd" - "Cele\try-6, Cele\try-1" - "Mmus\Klk15, Mmus\Klk9" "Hsap\CFD, Hsap\TPSD1, Hsap\KLK15, Hsap\KLK9" FBgn0010350 CdsA CDP diglyceride synthetase http://flybase.org/reports/FBgn0010350 FBgn0035841 protein_coding_gene phosphatidate cytidylyltransferase activity ; GO:0004605 | inferred from sequence or structural similarity phosphatidate cytidylyltransferase activity ; GO:0004605 | inferred from direct assay "sperm individualization ; GO:0007291 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from mutant phenotype cell growth ; GO:0016049 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype phototransduction ; GO:0007602 | non-traceable author statement phosphatidylglycerol biosynthetic process ; GO:0006655 | inferred from biological aspect of ancestor with PANTHER:PTN000349517 CDP-diacylglycerol biosynthetic process ; GO:0016024 | non-traceable author statement CDP-diacylglycerol biosynthetic process ; GO:0016024 | inferred from biological aspect of ancestor with PANTHER:PTN000349517 trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype inferred from genetic interaction with Arr2 regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype thermotaxis ; GO:0043052 | inferred from direct assay lipid biosynthetic process ; GO:0008610 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000349519 "cdsA, cds, eye-CDS, eye-cds, CDS, CG7962, CdsA" "IPR000374:Phosphatidate cytidylyltransferase, IPR016720:Phosphatidate cytidylyltransferase, eukaryota" CG7962 11-Aug-17 DroID_v2017_08 "Drer\cds2, Drer\cds1" Scer\CDS1 Cele\cdgs-1 "Xtro\cds2, Xtro\cds1" "Mmus\Cds2, Mmus\Cds1" "Hsap\CDS1, Hsap\CDS2" adult stage " adult head

, photoreceptor cell R1--8

, ocellus

" "neurophysiology defective,viable,visual behavior defective,thermotaxis behavior defective,wild-type,lethal,recessive" "photoreceptor cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,rhabdomere,eye photoreceptor cell,ommatidium,salivary gland,lipid particle | ectopic,lipid particle | ectopicppl.PP,lipid particle | ectopicelav.PU,terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0036774 mRpS26 mitochondrial ribosomal protein S26 http://flybase.org/reports/FBgn0036774 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with protein_id:CAC20860 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with protein_id:CAC20860 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with protein_id:CAC20860 "MRP-S26, CG7354, mRpS26" IPR026140:28S ribosomal protein S26 CG7354 11-Aug-17 DroID_v2017_08 Drer\mrps26 - Cele\mrps-26 - Mmus\Mrps26 Hsap\MRPS26 viable FBgn0030050 CG12111 - http://flybase.org/reports/FBgn0030050 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - CG12111 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG12111 11-Aug-17 DroID_v2017_08 "Drer\hbl3, Drer\si:ch211-170d8.5, Drer\hbl4, Drer\clec3ba, Drer\illr1, Drer\si:ch211-232p21.6, Drer\zgc:174904, Drer\clec11a, Drer\zmp:0000000937, Drer\colec11, Drer\si:ch73-343l4.8, Drer\clec3bb, Drer\si:dkey-26c10.5, Drer\illr2, Drer\hbl2, Drer\si:ch73-122g19.1, Drer\hbl1, Drer\selp, Drer\bcan" - "Cele\clec-9, Cele\clec-38, Cele\clec-7, Cele\clec-198, Cele\F52E1.2, Cele\clec-50, Cele\clec-17, Cele\clec-26, Cele\clec-78, Cele\clec-149, Cele\clec-4, Cele\clec-39, Cele\clec-31, Cele\clec-28" "Xtro\ncan, Xtro\clec10a" "Mmus\Fcer2a, Mmus\Clec4d, Mmus\Mbl1, Mmus\Bcan, Mmus\Clec4a4, Mmus\Klrb1b, Mmus\Cd209b, Mmus\Ncan, Mmus\Clec11a, Mmus\Gm156, Mmus\Klrb1c, Mmus\Colec10, Mmus\Clec4g, Mmus\Asgr2, Mmus\Clec12b, Mmus\Clec9a, Mmus\Sftpa1, Mmus\Colec11, Mmus\Clec3b, Mmus\Cd209e, Mmus\Clec5a, Mmus\Cd209c, Mmus\Clec4n, Mmus\Clec10a, Mmus\Clec4e, Mmus\Cd209a, Mmus\Mbl2, Mmus\Clec2h, Mmus\Colec12, Mmus\Sftpd, Mmus\Sell" "Hsap\CLEC4C, Hsap\BCAN, Hsap\CLEC3A, Hsap\SFTPA1, Hsap\SFTPD, Hsap\CLEC5A, Hsap\CLEC11A, Hsap\COLEC11, Hsap\CLEC6A, Hsap\CLEC17A, Hsap\SFTPA2, Hsap\CLEC4E, Hsap\CLEC4A, Hsap\MBL2, Hsap\COLEC12, Hsap\FCER2, Hsap\COLEC10, Hsap\CLEC4D" viable FBgn0087013 Karybeta3 Karyopherin beta 3 http://flybase.org/reports/FBgn0087013 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 protein transmembrane transporter activity ; GO:0008320 | inferred from sequence or structural similarity "ribosomal protein import into nucleus ; GO:0006610 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 protein import into nucleus, translocation ; GO:0000060 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 protein import into nucleus ; GO:0006606 | inferred from sequence or structural similarity" microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from sequence or structural similarity nuclear periphery ; GO:0034399 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000055427 "l(3)82CDd, l(3)j3A4, l(3)j7E8, CG1059, Karybeta3, Karbeta3, Kary-beta3" "IPR000357:HEAT repeat, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR021133:HEAT, type 2" CG1059 11-Aug-17 DroID_v2017_08 Drer\kpnb3 Scer\PSE1 Cele\imb-3 Xtro\ipo5 "Mmus\Ranbp6, Mmus\Ipo5" "Hsap\IPO5, Hsap\RANBP6" DRSC12355 IE 5.159312348 -0.149857756 4.402984192 -0.790337049 -0.769482702 -0.018088016 FBgn0036544 sff sugar-free frosting http://flybase.org/reports/FBgn0036544 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with WB:WBGene00004719 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678822" protein phosphorylation ; GO:0006468 | non-traceable author statement neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein N-linked glycosylation ; GO:0006487 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:18994 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:18994 "sff, CG6114" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG6114 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-205o12.1, Drer\pimr154, Drer\LOC568680, Drer\pimr155, Drer\si:dkey-16p21.7, Drer\pimr109, Drer\pimr212, Drer\pimr158, Drer\pimr148, Drer\pimr55, Drer\pimr126, Drer\pimr140, Drer\pimr138, Drer\pimr135, Drer\prkaa1, Drer\pimr120, Drer\si:dkey-33c12.5, Drer\pimr50, Drer\pimr213, Drer\LOC562898, Drer\pimr162, Drer\si:ch211-122l14.7, Drer\LOC100537940, Drer\LOC100536890, Drer\pimr65, Drer\pimr70, Drer\pimr144, Drer\pimr63, Drer\pimr157, Drer\brsk2b, Drer\pimr51, Drer\LOC792657, Drer\LOC799072, Drer\brsk2a, Drer\LOC100537673, Drer\LOC100329231, Drer\si:dkey-265c15.9, Drer\pimr53, Drer\si:ch211-255p10.4, Drer\si:rp71-1l17.1, Drer\pimr167, Drer\si:dkey-1p9.2, Drer\pimr108, Drer\si:dkey-265c15.7, Drer\pimr151, Drer\pimr132, Drer\pimr179, Drer\LOC100537706, Drer\LOC103911514, Drer\si:dkey-58b18.7, Drer\si:dkey-112g5.3, Drer\pimr152, Drer\pimr141, Drer\pimr110, Drer\LOC100150106, Drer\si:dkey-58b18.10, Drer\LOC108192014, Drer\pim1, Drer\LOC797340, Drer\pimr66, Drer\LOC798566" "Scer\HSL1, Scer\FRK1, Scer\SNF1, Scer\GIN4, Scer\KCC4" "Cele\prk-2, Cele\aak-2, Cele\sad-1, Cele\prk-1" "Xtro\brsk2, Xtro\brsk1" "Mmus\Prkaa2, Mmus\Brsk2, Mmus\Pim1, Mmus\Pim2, Mmus\Brsk1, Mmus\Prkaa1" "Hsap\PIM2, Hsap\PRKAA1, Hsap\BRSK2, Hsap\BRSK1, Hsap\PRKAA2" "partially lethal - majority live,gravitaxis defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuromuscular junction,embryonic/larval hemocyte | third instar larval stage" FBgn0036111 Aps Aps http://flybase.org/reports/FBgn0036111 protein_coding_gene bis(5'-adenosyl)-pentaphosphatase activity ; GO:0034432 | inferred from biological aspect of ancestor with PANTHER:PTN000290327 endopolyphosphatase activity ; GO:0000298 | inferred from biological aspect of ancestor with PANTHER:PTN000290327 diphosphoinositol-polyphosphate diphosphatase activity ; GO:0008486 | inferred from direct assay m7G(5')pppN diphosphatase activity ; GO:0050072 | inferred from biological aspect of ancestor with PANTHER:PTN000290327 bis(5'-adenosyl)-hexaphosphatase activity ; GO:0034431 | inferred from biological aspect of ancestor with PANTHER:PTN000290327 nucleotide metabolic process ; GO:0009117 | inferred from direct assay adenosine 5'-(hexahydrogen pentaphosphate) catabolic process ; GO:1901911 | inferred from biological aspect of ancestor with PANTHER:PTN000290327 response to starvation ; GO:0042594 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype diadenosine hexaphosphate catabolic process ; GO:1901909 | inferred from biological aspect of ancestor with PANTHER:PTN000290327 diphosphoinositol polyphosphate metabolic process ; GO:0071543 | inferred from biological aspect of ancestor with PANTHER:PTN000290327 glucose homeostasis ; GO:0042593 | inferred from mutant phenotype inositol phosphate metabolic process ; GO:0043647 | inferred from direct assay regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from mutant phenotype diadenosine pentaphosphate catabolic process ; GO:1901907 | inferred from biological aspect of ancestor with PANTHER:PTN000290327 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG6391, anon-WO0118547.266, Aps" "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like, IPR020084:NUDIX hydrolase, conserved site" CG6391 11-Aug-17 DroID_v2017_08 "Drer\nudt4a, Drer\nudt4b, Drer\nudt3b, Drer\nudt3a" Scer\DDP1 "Cele\R119.3, Cele\Y92H12BL.5" Xtro\nudt4 "Mmus\Nudt10, Mmus\Anks1, Mmus\Nudt4, Mmus\Nudt11, Mmus\Nudt3" "Hsap\NUDT11, Hsap\NUDT3, Hsap\NUDT4, Hsap\NUDT10" viable FBgn0039091 CG10182 - http://flybase.org/reports/FBgn0039091 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG10182 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG10182 11-Aug-17 DroID_v2017_08 Drer\oacyl - "Cele\oac-55, Cele\nrf-6, Cele\oac-31, Cele\oac-6, Cele\rhy-1, Cele\oac-32, Cele\oac-9, Cele\oac-54, Cele\oac-3, Cele\oac-7, Cele\oac-39, Cele\oac-46, Cele\oac-14, Cele\ndg-4, Cele\oac-53, Cele\oac-20, Cele\oac-50, Cele\oac-5" Xtro\LOC101732251 Mmus\Oacyl - viable FBgn0051373 CG31373 - http://flybase.org/reports/FBgn0051373 protein_coding_gene peptide deformylase activity ; GO:0042586 | inferred from biological aspect of ancestor with PANTHER:PTN000048655 co-translational protein modification ; GO:0043686 | inferred from biological aspect of ancestor with PANTHER:PTN000048655 N-terminal protein amino acid modification ; GO:0031365 | inferred from biological aspect of ancestor with PANTHER:PTN000048655 - "PDF, CG6482, CG31373" IPR023635:Peptide deformylase CG31373 11-Aug-17 DroID_v2017_08 Drer\pdf - - Xtro\pdf Mmus\Pdf Hsap\PDF lethal FBgn0086604 CG12484 - http://flybase.org/reports/FBgn0086604 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "CG12484, CG33041, CT32777, CG30143, 12484" "IPR013162:CD80-like, immunoglobulin C2-set, IPR013106:Immunoglobulin V-set domain, IPR007110:Immunoglobulin-like domain, IPR003961:Fibronectin type III, IPR003599:Immunoglobulin subtype, IPR003598:Immunoglobulin subtype 2, IPR013783:Immunoglobulin-like fold" CG12484 11-Aug-17 DroID_v2017_08 - - - - - "Hsap\MERTK, Hsap\PSG1" "viable,visible" "chaeta,supernumerary" FBgn0039629 CG11842 - http://flybase.org/reports/FBgn0039629 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available "SP68, CG11842" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11842 11-Aug-17 DroID_v2017_08 Drer\f10 - "Cele\try-1, Cele\svh-1" - "Mmus\Hgfac, Mmus\Habp2, Mmus\Plat, Mmus\F12, Mmus\Prss12, Mmus\Plau" - "viable,fertile" FBgn0032059 PrBP Prenyl-binding protein http://flybase.org/reports/FBgn0032059 protein_coding_gene "3',5'-cyclic-nucleotide phosphodiesterase activity ; GO:0004114 | inferred from electronic annotation with InterPro:IPR017287 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VFI9" visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR017287 mushroom body development ; GO:0016319 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG9296, PrBP, DmPrBP/delta, DmPrBP" "IPR008015:GMP phosphodiesterase, delta subunit, IPR014756:Immunoglobulin E-set, IPR017287:Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit" CG9296 11-Aug-17 DroID_v2017_08 Drer\pde6d "Scer\TVP15, Scer\NSE5, Scer\MND1" Cele\pdl-1 - Mmus\Pde6d Hsap\PDE6D "neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "optic lobe,eye,adult mushroom body,mesothoracic tergum" DRSC25862 IK 0.572761068 1.731020089 -0.560945528 0.873811422 1.102042542 1.656097109 FBgn0038358 CG4525 - http://flybase.org/reports/FBgn0038358 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with MGI:MGI:2444853 cilium assembly ; GO:0060271 | inferred from sequence model cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:2444853 intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:2444853 "CG4525, TTC26" "IPR011990:Tetratricopeptide-like helical domain, IPR030511:Tetratricopeptide repeat protein 26" CG4525 11-Aug-17 DroID_v2017_08 Drer\ttc26 - Cele\dyf-13 Xtro\ttc26 Mmus\Ttc26 Hsap\TTC26 viable FBgn0039557 CG12259 - http://flybase.org/reports/FBgn0039557 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:18786 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:18786 CG12259 IPR007005:XAP5 protein CG12259 11-Aug-17 DroID_v2017_08 Drer\fam50a - Cele\C47E8.4 Xtro\fam50a "Mmus\Fam50a, Mmus\Fam50b" "Hsap\FAM50B, Hsap\FAM50A" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0010548 Aldh-III Aldehyde dehydrogenase type III http://flybase.org/reports/FBgn0010548 FBgn0033180 protein_coding_gene aldehyde dehydrogenase [NAD(P)+] activity ; GO:0004030 | inferred from electronic annotation with InterPro:IPR012394 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR012394, InterPro:IPR015590, InterPro:IPR016160, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163, InterPro:IPR029510 cellular aldehyde metabolic process ; GO:0006081 | inferred from electronic annotation with InterPro:IPR012394" lipid particle ; GO:0005811 | inferred from direct assay "CT41571, ALDH-III, CG11140, FALDH, Dhap, l(2)03610, Aldh-III, ALDH" "IPR012394:Aldehyde dehydrogenase NAD(P)-dependent, IPR015590:Aldehyde dehydrogenase domain, IPR016160:Aldehyde dehydrogenase, cysteine active site, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR029510:Aldehyde dehydrogenase, glutamic acid active site" CG11140 11-Aug-17 DroID_v2017_08 "Drer\aldh3a2b, Drer\aldh3a1, Drer\aldh3b2, Drer\aldh3b1, Drer\aldh3a2a" "Scer\HFD1, Scer\ALD2" "Cele\alh-4, Cele\alh-5" "Xtro\aldh3a2, Xtro\aldh3b1" "Mmus\Aldh3b1, Mmus\Aldh3a1, Mmus\Aldh3a2, Mmus\Aldh3b2, Mmus\Aldh3b3" "Hsap\ALDH3A2, Hsap\ALDH3B2, Hsap\ALDH3A1, Hsap\ALDH3B1" "partially lethal - majority die,lethal,recessive,chemical sensitive,behavior defective,viable,partially lethal,conditional,developmental rate defective" crystal cell FBgn0001494 l(1)10Bh lethal (1) 10Bh http://flybase.org/reports/FBgn0001494 - gene - - - "10Bh, l(1)GLM21, l(1)MSV22, l(1)MSV12, l(1)GLM20M21, l(1)G21, l(1)10Bh" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,female sterile,lethal,partially,female fertile,male fertile,lethal - all die before end of pupal stage,some die during pupal stage" "primary spermatocyte cyst,spermatid,major mitochondrial derivative,minor mitochondrial derivative" FBgn0036839 SmydA-2 "SET and MYND domain containing, arthropod-specific, member 2" http://flybase.org/reports/FBgn0036839 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 - "SmydA-2, CG18136" "IPR001214:SET domain, IPR002893:Zinc finger, MYND-type" CG18136 11-Aug-17 DroID_v2017_08 "Drer\smyd2a, Drer\smyd1b, Drer\smyd4, Drer\smyd1a, Drer\smyd3, Drer\smyd2b" "Scer\SET6, Scer\SET5" "Cele\set-30, Cele\set-18" "Xtro\smyd5, Xtro\smyd1, Xtro\smyd4" "Mmus\Smyd1, Mmus\Smyd4, Mmus\Smyd5, Mmus\Smyd2, Mmus\Smyd3" "Hsap\SMYD4, Hsap\SMYD3, Hsap\SMYD2, Hsap\SMYD5, Hsap\SMYD1" "partially lethal - majority die,some die during pupal stage" FBgn0004545 l(4)102CDp lethal (4) 102CDp http://flybase.org/reports/FBgn0004545 - gene - - - "l(4)CDp, l(4)31, l(4)102CDp" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0069222 gl(2R)243-17 gl(2R)243-17 http://flybase.org/reports/FBgn0069222 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2R)243-17 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,denticle belt" FBgn0033901 O-fut1 O-fucosyltransferase 1 http://flybase.org/reports/FBgn0033901 protein_coding_gene Notch binding ; GO:0005112 | inferred from direct assay fucosyltransferase activity ; GO:0008417 | inferred from direct assay peptide-O-fucosyltransferase activity ; GO:0046922 | traceable author statement fucosyltransferase activity ; GO:0008417 | inferred from sequence or structural similarity with UniProtKB:Q9H488 peptide-O-fucosyltransferase activity ; GO:0046922 | inferred from direct assay "single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype protein O-linked fucosylation ; GO:0036066 | inferred from direct assay O-glycan processing ; GO:0016266 | traceable author statement embryo development ; GO:0009790 | non-traceable author statement protein catabolic process ; GO:0030163 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype protein O-linked glycosylation ; GO:0006493 | inferred from sequence or structural similarity with UniProtKB:Q9H488 regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | non-traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement" endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | NOT inferred from direct assay cytoplasm ; GO:0005737 | inferred by curator from GO:0046922 cytoplasmic vesicle ; GO:0031410 | inferred from direct assay "O-fut1, Ofut1, OFUT1, nti, CG12366, 4R6, ntc, AAF58290.1, O-FUT1, l(2)SH2260, l(2)SH2 2260, O-fut, Ofut-1, OFut1, o-fut1" IPR019378:GDP-fucose protein O-fucosyltransferase CG12366 11-Aug-17 DroID_v2017_08 Drer\pofut1 - Cele\C15C7.7 Xtro\pofut1 Mmus\Pofut1 Hsap\POFUT1 " larval stage , embryonic stage | stage 3-11 , embryonic stage | stage 13 , embryonic stage | stage 1-12 " " ventral thoracic disc

uniform , organism

, lymph gland

, dorsal mesothoracic disc

uniform , germline cell

, eye disc

, antennal disc

uniform , central nervous system

, dorsal metathoracic disc

uniform ,

ubiquitous " "neuroanatomy defective,viable,fertile,lethal,recessive,visible,somatic clone,lethal - all die before end of first instar larval stage,germline clone,maternal effect,some die during first instar larval stage,neurogenic phenotype" "embryonic/larval optic lobe,wing,somatic clone,wing vein,macrochaeta,scutellar bristle,neuron,germline clone,non-rescuable maternal effect,wing margin,intestinal stem cell,supernumerary,eye,leg,distal,mesothoracic tergum & microchaetaap-md544,mesothoracic tergum & eo neuronap-md544,mesothoracic tergum & thecogen cellap-md544,microchaeta,S2 cell-line,chaeta" FBgn0003559 su(f) suppressor of forked http://flybase.org/reports/FBgn0003559 "FBgn0028293, FBan0017170" protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000463331 mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR008847 RNA 3'-end processing ; GO:0031123 | inferred from biological aspect of ancestor with PANTHER:PTN000463331 mRNA cleavage ; GO:0006379 | inferred from biological aspect of ancestor with PANTHER:PTN000463331 positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:1903220 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000463331 mRNA cleavage stimulating factor complex ; GO:0005848 | inferred from direct assay "su-f, CstF-77, CG17170, l(1)su(f), su[+]-f, l(1)R-9-18, EC235, R-9-18, 3-DES, 3DES, l(1)3DES, R9-18, SU-f, l3DES, 29, 28, 19, l(1)G0393, l(1)X3, l(1)X1, l(1)EC235, l(1)20Eb, su(f), Su(f), CstF77, Cstf77" "IPR003107:HAT (Half-A-TPR) repeat, IPR011990:Tetratricopeptide-like helical domain, IPR008847:Suppressor of forked" CG17170 11-Aug-17 DroID_v2017_08 Drer\cstf3 Scer\RNA14 Cele\suf-1 Xtro\cstf3 Mmus\Cstf3 Hsap\CSTF3 embryonic stage -- adult stage "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,cell lethal,germline clone,wild-type,visible,heat sensitive,body color defective,male,male fertile,female sterile,mating defective,hypoactive,female,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death" "adult thorax,heat sensitive,wing,macrochaeta,larval brain & mitotic cell cycle,eye,head,gena,leg,prothoracic leg,scutum,ovariole,follicle cell,microchaeta,anterior,dorsal,interfollicle cell,germline cyst,germline cell,female,egg chamber,imaginal disc,embryonic/larval brain,embryonic/larval optic lobe,nuclear chromosome & larval brain | conditional ts,mitotic cell cycle & larval brain | conditional ts,imaginal disc & mitotic metaphase | conditional ts,imaginal disc & spindle | conditional ts,imaginal disc & metaphase & condensed nuclear chromosome | conditional ts,eye-antennal disc,antennal disc" DRSC20907 I 0.157504898 1.619294608 -0.372092803 1.491350254 -0.026694376 0.00066504 FBgn0002809 ms(1)413 male sterile (1) 413 http://flybase.org/reports/FBgn0002809 - gene - - - "ms(1)RD11, ms(1)682, ms(1)413" - - 11-Aug-17 DroID_v2017_08 - - - - - - "male sterile,meiotic cell cycle defective,male,behavior defective" "meiotic cell cycle | male,spermatocyte,spermatid,Nebenkern,Nebenkern derivative,spermatid & centriole" FBgn0003880 tu(3)be benign tumor in chromosome 3 http://flybase.org/reports/FBgn0003880 FBgn0000169 gene - - - "be, be-3, tu(3)be" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,melanotic mass phenotype" FBgn0032744 Ttc19 Tetratricopeptide repeat domain 19 http://flybase.org/reports/FBgn0032744 protein_coding_gene - optomotor response ; GO:0071632 | inferred from mutant phenotype mitochondrial respiratory chain complex III biogenesis ; GO:0097033 | inferred from mutant phenotype mitochondrial respiratory chain complex III assembly ; GO:0034551 | inferred from biological aspect of ancestor with PANTHER:PTN000321934 mitochondrial respiratory chain complex III assembly ; GO:0034551 | inferred from mutant phenotype jump response ; GO:0007630 | inferred from mutant phenotype mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000321934 mitochondrion ; GO:0005739 | inferred from direct assay "CG15173, Ttc19, cg15173, TTC19" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain" CG15173 11-Aug-17 DroID_v2017_08 "Drer\klc2, Drer\klc3, Drer\klc4, Drer\nphp3, Drer\appbp2, Drer\klc1a, Drer\ttc19" - Cele\ddl-3 "Xtro\nphp3, Xtro\appbp2, Xtro\klc1, Xtro\ttc19" "Mmus\Klc4, Mmus\Klc1, Mmus\Ttc19, Mmus\Klc2, Mmus\Klc3, Mmus\Appbp2, Mmus\Nphp3" "Hsap\KLC1, Hsap\NPHP3, Hsap\KLC2, Hsap\KLC4, Hsap\APPBP2, Hsap\TTC19, Hsap\KLC3" "viable,fertile,short lived,semi-sterile,bang sensitive,locomotor behavior defective,visual behavior defective" FBgn0021816 l(2)k16406 lethal (2) k16406 http://flybase.net/reports/FBgn0021816.html gene 11-Aug-17 DroID_v2017_08 "lethal,recessive" FBgn0000940 fs(2)A10 female sterile (2) A10 http://flybase.org/reports/FBgn0000940 - gene - - - fs(2)A10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0002331 l(3)87Ad lethal (3) 87Ad http://flybase.org/reports/FBgn0002331 - gene - - - "ck11, l(3)ck11, l(3)87Ad" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0065650 l(2)SH0734 lethal (2) SH0734 http://flybase.org/reports/FBgn0065650 gene - - - "l(2)SH0734, l(2)SH2 0734" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0015269 Nf1 Neurofibromin 1 http://flybase.org/reports/FBgn0015269 - protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from direct assay positive regulation of GTPase activity ; GO:0043547 | inferred from electronic annotation with InterPro:IPR028553 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype perineurial glial growth ; GO:0042066 | inferred from genetic interaction with poe inferred from genetic interaction with ine negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype positive regulation of adenylate cyclase activity ; GO:0045762 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype cAMP-mediated signaling ; GO:0019933 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype regulation of Ras protein signal transduction ; GO:0046578 | inferred from mutant phenotype Ras protein signal transduction ; GO:0007265 | inferred from genetic interaction with Sos inferred from genetic interaction with Ras85D regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 intrinsic component of the cytoplasmic side of the plasma membrane ; GO:0031235 | inferred from biological aspect of ancestor with PANTHER:PTN000022879 "dNF1, NF1, CG8318, NF-1, Nf-1, Nf1, nf1, dNf1, FBpp0084326" "IPR001251:CRAL-TRIO lipid binding domain, IPR001936:Ras GTPase-activating protein, IPR008936:Rho GTPase activation protein, IPR028553:Neurofibromin, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG8318 11-Aug-17 DroID_v2017_08 "Drer\rasa2, Drer\rasa3, Drer\si:dkeyp-72a4.1, Drer\nf1b, Drer\nf1a, Drer\iqgap2" "Scer\BUD2, Scer\IRA1, Scer\IRA2" Cele\gap-1 "Xtro\rasa2, Xtro\nf1" "Mmus\Rasa3, Mmus\Iqgap2, Mmus\Nf1, Mmus\Rasa2" "Hsap\RASA3, Hsap\NF1, Hsap\IQGAP2, Hsap\RASA2" " larval stage , embryonic stage " imaginal disc

" embryonic stage , larval stage " imaginal disc

"viable,fertile,small body,male limited,memory defective,locomotor rhythm defective,learning defective,behavior defective,short lived,heat stress response defective,heat sensitive,oxidative stress response defective,neuroanatomy defective,long lived,wild-type,semi-sterile,size defective,neurophysiology defective,dominant,decreased cell size" "surface associated glial cell,eye photoreceptor cell,neuromuscular junction | larval stage,pupa,NMJ bouton,supernumerary,heart primordium,wing,wing disc" FBgn0039380 CG5890 - http://flybase.org/reports/FBgn0039380 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" "neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - CG5890 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG5890 11-Aug-17 DroID_v2017_08 "Drer\guca1b, Drer\LOC101886535, Drer\kcnip1a, Drer\kcnip3a, Drer\rcvrna, Drer\rcvrnb, Drer\hpcal1, Drer\guca1g, Drer\vsnl1b, Drer\hpcal4, Drer\ncaldb, Drer\kcnip3b, Drer\kcnip1b, Drer\guca1a, Drer\ncs1a, Drer\si:ch211-245j22.3, Drer\guca1d, Drer\guca1c, Drer\efcab1, Drer\si:ch211-145b13.5, Drer\kcnip2, Drer\si:ch211-103a14.5, Drer\ncalda, Drer\guca1e, Drer\rcvrn3, Drer\hpca, Drer\rcvrn2, Drer\kcnip4, Drer\ncs1b, Drer\usp32, Drer\vsnl1a" Scer\FRQ1 "Cele\ncs-5, Cele\ncs-3, Cele\ncs-4, Cele\ncs-6, Cele\ncs-1, Cele\ncs-2, Cele\ncs-7" "Xtro\ncald, Xtro\guca1b, Xtro\guca1a, Xtro\hpcal1, Xtro\ncs1, Xtro\rcvrn.2, Xtro\kcnip4, Xtro\guca1c, Xtro\efcab1, Xtro\kcnip2, Xtro\kcnip1, Xtro\hpca, Xtro\kcnip3, Xtro\vsnl1" "Mmus\Kcnip1, Mmus\1700109H08Rik, Mmus\Hpcal4, Mmus\Ncs1, Mmus\Guca1b, Mmus\Kcnip4, Mmus\Kcnip3, Mmus\Kcnip2, Mmus\Hpca, Mmus\Rcvrn, Mmus\Vsnl1, Mmus\Efcab1, Mmus\Guca1a, Mmus\Ncald, Mmus\Usp32, Mmus\Hpcal1" "Hsap\GUCA1B, Hsap\NCS1, Hsap\HPCAL1, Hsap\NCALD, Hsap\HPCAL4, Hsap\KCNIP2, Hsap\GUCA1A, Hsap\GUCA1C, Hsap\EFCAB1, Hsap\KCNIP1, Hsap\HPCA, Hsap\KCNIP4, Hsap\RCVRN, Hsap\VSNL1, Hsap\USP32, Hsap\KCNIP3" viable DRSC15909 K -0.064977609 -0.900281667 -0.473872207 0.458190839 1.852230101 -0.560590616 FBgn0039637 Ctl2 Choline transporter-like 2 http://flybase.org/reports/FBgn0039637 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG11880, CTLH2, Ctl2, DmCTL2" IPR007603:Choline transporter-like CG11880 11-Aug-17 DroID_v2017_08 "Drer\slc44a4, Drer\si, Drer\slc44a2, Drer\slc44a1b, Drer\slc44a5b, Drer\zgc:63569, Drer\slc44a5a, Drer\slc44a1a" Scer\PNS1 Cele\chtl-1 "Xtro\slc44a4, Xtro\slc44a2, Xtro\slc44a5, Xtro\slc44a1" "Mmus\Slc44a1, Mmus\Slc44a5, Mmus\Slc44a2, Mmus\Slc44a4, Mmus\Slc44a3" "Hsap\SLC44A4, Hsap\SLC44A5, Hsap\SLC44A1, Hsap\SLC44A2, Hsap\SLC44A3" viable FBgn0034314 nopo no poles http://flybase.org/reports/FBgn0034314 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR011016 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with ben DNA polymerase binding ; GO:0070182 | inferred from physical interaction with DNApol-η zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1096377" "positive regulation of mitotic cell cycle, embryonic ; GO:0045977 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:1096377 cell death ; GO:0008219 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "CG5140, nopo, TRIP, Nopo, NOPO" "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011016:Zinc finger, RING-CH-type" CG5140 11-Aug-17 DroID_v2017_08 "Drer\lnx1, Drer\rnf2, Drer\traip, Drer\lnx2b" - "Cele\spat-3, Cele\ZK637.14, Cele\B0432.13" "Xtro\traip, Xtro\rnf2" "Mmus\Ring1, Mmus\Brca1, Mmus\Traip, Mmus\Rnf2" "Hsap\RING1, Hsap\TRAIP, Hsap\BRCA1, Hsap\RNF2" "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,lethal - all die during embryonic stage,maternal effect,viable,increased cell death,partially lethal,majority die during embryonic stage,developmental rate defective,heat sensitive" "centrosome | non-rescuable maternal effect,spindle | non-rescuable maternal effect,mitotic spindle | maternal effect,eye,wing margin" FBgn0262614 pyd polychaetoid http://flybase.org/reports/FBgn0262614 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) cell adhesion molecule binding ; GO:0050839 | inferred from physical interaction with kirre guanylate kinase activity ; GO:0004385 | inferred from sequence or structural similarity with HGNC:11827 inferred from sequence or structural similarity with SGD:S000002862 WW domain binding ; GO:0050699 | inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) inferred from physical interaction with Su(dx) "apical protein localization ; GO:0045176 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype JNK cascade ; GO:0007254 | non-traceable author statement establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype protein localization to cell cortex ; GO:0072697 | inferred from direct assay nephrocyte diaphragm assembly ; GO:0036059 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype regulation of JNK cascade ; GO:0046328 | non-traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype dorsal closure ; GO:0007391 | non-traceable author statement head involution ; GO:0008258 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype fusion cell fate specification ; GO:0035156 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype regulation of cell adhesion ; GO:0030155 | inferred from mutant phenotype inferred from genetic interaction with rst inferred from genetic interaction with shg dorsal closure ; GO:0007391 | inferred from mutant phenotype" adherens junction ; GO:0005912 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay adherens junction ; GO:0005912 | non-traceable author statement apical part of cell ; GO:0045177 | inferred from direct assay cell-cell adherens junction ; GO:0005913 | inferred from direct assay adherens junction ; GO:0005912 | traceable author statement axon ; GO:0030424 | inferred from direct assay nephrocyte diaphragm ; GO:0005917 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "pyd, Pyd, CG43140, ZO-1, CT36877, pyd(Z01), Tamou, Pyd/ZO-1, CG9763, ZO1, tam, dzo-1, DZO-1, xvt, Pch, CG9729, CG12409, CG11962, CG11782, CG31349, polychaetoid, CG9731" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000906:ZU5 domain, IPR001478:PDZ domain, IPR008144:Guanylate kinase-like domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR011511:Variant SH3 domain, IPR001452:SH3 domain" CG43140 11-Aug-17 DroID_v2017_08 "Drer\tjp1b, Drer\tjp1a, Drer\tjp3, Drer\tjp2b, Drer\tjp2a, Drer\dlg5b.1" - "Cele\zoo-1, Cele\magu-4" "Xtro\tjp2, Xtro\tjp1, Xtro\tjp3" "Mmus\Tjp3, Mmus\Tjp2, Mmus\Tjp1" "Hsap\TJP2, Hsap\TJP1, Hsap\TJP3" " embryonic stage -- adult stage , larval stage && pupal stage , larval stage | third instar " dorsal mesothoracic disc

" larval stage && pupal stage , larval stage | third instar , embryonic stage " dorsal mesothoracic disc

DRSC14509 K 0.087400407 0.184327963 0.014396083 0.047489705 0.231123254 1.516905631 FBgn0265274 Inx3 Innexin 3 http://flybase.org/reports/FBgn0265274 protein_coding_gene gap junction channel activity ; GO:0005243 | inferred from direct assay gap junction channel activity ; GO:0005243 | inferred by curator from GO:0005921 intercellular transport ; GO:0010496 | inferred from direct assay dorsal closure ; GO:0007391 | inferred from mutant phenotype lateral plasma membrane ; GO:0016328 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay gap junction ; GO:0005921 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement "FBpp0084719, inx3, CG1448, Inx3, inx-3, Dm-inx3, Ix3, INX-3, anon-EST:fe2B11" IPR000990:Innexin CG1448 11-Aug-17 DroID_v2017_08 "Drer\panx1b, Drer\panx3" - "Cele\inx-5, Cele\eat-5, Cele\che-7, Cele\inx-10, Cele\inx-9, Cele\unc-7, Cele\inx-17, Cele\inx-16, Cele\inx-1, Cele\inx-12, Cele\inx-11, Cele\inx-18, Cele\inx-3, Cele\inx-6, Cele\inx-13, Cele\inx-19, Cele\unc-9, Cele\inx-2, Cele\inx-8, Cele\inx-15, Cele\inx-20, Cele\inx-14, Cele\inx-21, Cele\inx-22, Cele\inx-7" - - - DRSC14857 I 0.538790899 1.6226549 0.158624786 1.061106873 0.11127459 -0.148987143 FBgn0051617 His1:CG31617 His1:CG31617 http://flybase.org/reports/FBgn0051617 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG31617, His1:CG31617" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG31617 11-Aug-17 DroID_v2017_08 "Drer\histh1l, Drer\si:dkey-261m9.12, Drer\zgc:163061, Drer\h1f0, Drer\si:dkey-108k21.21, Drer\h1m, Drer\zgc:110216, Drer\si:dkey-108k21.10, Drer\zgc:110425, Drer\zgc:153405, Drer\h1fx, Drer\si:ch73-36p18.1, Drer\si:dkey-108k21.14, Drer\si:ch211-113a14.24, Drer\si:ch1073-159d7.7" Scer\HHO1 "Cele\his-24, Cele\hil-2, Cele\hil-6, Cele\hil-3, Cele\hil-1, Cele\hil-4, Cele\hil-5" - "Mmus\H1foo, Mmus\H1fx, Mmus\Hist1h1t, Mmus\Hist1h1e, Mmus\Hist1h1a, Mmus\Hils1, Mmus\Hist1h1c, Mmus\Hist1h1b, Mmus\Hist1h1d, Mmus\H1fnt" "Hsap\HIST1H1E, Hsap\HIST1H1T, Hsap\H1FOO, Hsap\HIST1H1A, Hsap\HIST1H1B, Hsap\HIST1H1D, Hsap\H1F0, Hsap\HIST1H1C, Hsap\H1FX, Hsap\H1FNT" DRSC21266 I 1.674501497 1.169573763 1.18066883 -0.601981771 -0.915227058 0.236375266 FBgn0010812 unc-45 uncoordinated 45 http://flybase.org/reports/FBgn0010812 FBgn0037545 protein_coding_gene - chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay somatic muscle development ; GO:0007525 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype myosin filament assembly ; GO:0031034 | inferred from mutant phenotype cellular response to heat ; GO:0034605 | inferred from direct assay - "dunc-45, DmUnc-45, l(3)03692, CG2708, Tom34, unc-45, dUNC-45, DmUNC-45, lincRNA.721" "IPR011989:Armadillo-like helical, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR016024:Armadillo-type fold, IPR019734:Tetratricopeptide repeat, IPR024660:UNC-45/Cro1/She4, central domain, IPR001440:Tetratricopeptide repeat 1" CG2708 11-Aug-17 DroID_v2017_08 "Drer\unc45a, Drer\unc45b" "Scer\SHE4, Scer\SGT2" Cele\unc-45 "Xtro\unc45a, Xtro\unc45b" "Mmus\Unc45a, Mmus\Unc45b" "Hsap\UNC45B, Hsap\TTC12, Hsap\UNC45A" "short lived,lethal,recessive,viable,fertile,lethal - all die before end of larval stage,some die during third instar larval stage" "myofibril,embryonic somatic muscle,adult heart,adult heart chamber 1,adult heart chamber 2,myofibrilHCH.Hand,embryonic/larval heart | P-stage,embryonic/larval heart | third instar larval stage" FBgn0085242 CG34213 - http://flybase.org/reports/FBgn0085242 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34213 "IPR008979:Galactose-binding domain-like, IPR033601:Nuclear receptor 2C2-associated protein" CG34213 11-Aug-17 DroID_v2017_08 "Drer\nr2c2ap, Drer\rpl38" - - "Xtro\rpl38, Xtro\nr2c2ap" "Mmus\Rpl38, Mmus\Nr2c2ap" Hsap\NR2C2AP FBgn0037653 CG11982 - http://flybase.org/reports/FBgn0037653 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:18154 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein autoubiquitination ; GO:0051865 | inferred from sequence or structural similarity with HGNC:18154 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 cellular_component ; GO:0005575 | no biological data available CG11982 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11982 11-Aug-17 DroID_v2017_08 "Drer\zgc:175214, Drer\rnf11a, Drer\rnf115, Drer\rnf11b, Drer\si:ch211-81a5.1, Drer\zswim2, Drer\rnf38, Drer\rnf130, Drer\znrf3, Drer\rnf165b, Drer\rnf6, Drer\rnf111, Drer\rnf215, Drer\rnf150a, Drer\rnf32, Drer\rnf24, Drer\pja2, Drer\rnf150, Drer\rlim, Drer\si:ch1073-392o20.1, Drer\rnf126, Drer\si:dkey-51a16.9, Drer\wu:fb39e10, Drer\rnf165a, Drer\rnf103, Drer\rnf44" "Scer\ASR1, Scer\YBR062C" Cele\Y54E10BR.3 "Xtro\rnf181, Xtro\rnf115, Xtro\rnf32, Xtro\rnf24, Xtro\rnf44, Xtro\chmp3, Xtro\rlim, Xtro\rnf126, Xtro\rnf11.2, Xtro\rnf111, Xtro\pja2, Xtro\rnf149, Xtro\znrf3, Xtro\rnf38, Xtro\rnf11" "Mmus\Rnf103, Mmus\Rnf181, Mmus\Rnf165, Mmus\Rnf44, Mmus\Rnf115, Mmus\Pja2, Mmus\Rnf126, Mmus\Pja1, Mmus\4930595M18Rik, Mmus\Rnf32, Mmus\Rnf38, Mmus\Rnf150, Mmus\Zswim2, Mmus\Rnf24, Mmus\Rnf149, Mmus\Rnf11, Mmus\Znrf3, Mmus\Rnf43, Mmus\Rnf6, Mmus\Rnf215, Mmus\Rnf122, Mmus\Rnf111, Mmus\Rlim, Mmus\Rnf130" "Hsap\CHMP3, Hsap\RNF149, Hsap\RNF38, Hsap\RNF126, Hsap\RNF215, Hsap\RNF43, Hsap\RNF122, Hsap\PJA2, Hsap\RLIM, Hsap\RNF44, Hsap\ZNRF3, Hsap\PJA1, Hsap\RNF130, Hsap\RNF111, Hsap\ZSWIM2, Hsap\RNF11, Hsap\RNF32, Hsap\RNF103, Hsap\RNF165, Hsap\RNF115, Hsap\RNF24, Hsap\RNF181, Hsap\RNF150, Hsap\RNF6" viable FBgn0259244 CG42342 - http://flybase.org/reports/FBgn0259244 protein_coding_gene - biological_process ; GO:0008150 | no biological data available - "CG42342, CG11769, CG42243, CG14888, CG14889, CG14890" IPR008160:Collagen triple helix repeat CG42342 11-Aug-17 DroID_v2017_08 "Drer\col27a1a, Drer\col6a4a, Drer\col5a2b, Drer\si:ch211-106n13.3, Drer\LOC101883924, Drer\col7a1l, Drer\col17a1b, Drer\col1a1b, Drer\col12a1b, Drer\si:dkey-61l1.4, Drer\col9a2, Drer\LOC100538221, Drer\col4a5, Drer\col1a2, Drer\col11a1a, Drer\col2a1a, Drer\wu:fc38h03, Drer\col11a1b, Drer\col28a1a, Drer\col5a1, Drer\col27a1b, Drer\col11a2, Drer\col5a2a, Drer\col6a2, Drer\col16a1, Drer\col6a3, Drer\si:dkeyp-44a8.4, Drer\col9a1a, Drer\si:dkey-225n22.4, Drer\col9a1b, Drer\LOC101884357, Drer\si:ch211-196i2.1, Drer\col1a1a, Drer\col4a6, Drer\col6a1, Drer\zmp:0000000760, Drer\col2a1b, Drer\col4a2, Drer\zgc:153049, Drer\col14a1a" - "Cele\col-95, Cele\col-183, Cele\col-44, Cele\col-94, Cele\col-93, Cele\col-87, Cele\col-34, Cele\col-3, Cele\col-154, Cele\col-117, Cele\col-114, Cele\col-119, Cele\col-33, Cele\col-96, Cele\sqt-3, Cele\col-108, Cele\dpy-13, Cele\col-133, Cele\col-124, Cele\dpy-4, Cele\bli-6, Cele\col-135, Cele\col-185, Cele\col-155, Cele\col-103, Cele\col-99, Cele\col-139, Cele\col-157, Cele\col-2, Cele\col-42, Cele\col-92, Cele\col-125" "Xtro\col4a5, Xtro\col7a1, Xtro\col4a6, Xtro\col14a1, Xtro\col27a1, Xtro\col4a1, Xtro\LOC100486063, Xtro\col3a1, Xtro\col1a1, Xtro\col4a2, Xtro\col2a1, Xtro\col24a1, Xtro\col11a2, Xtro\col1a2, Xtro\col5a1, Xtro\col6a2" "Mmus\Col20a1, Mmus\Col9a3, Mmus\Col11a1, Mmus\Col1a1, Mmus\Col17a1, Mmus\Col2a1, Mmus\Vwa1, Mmus\Col23a1, Mmus\Col6a5, Mmus\Col19a1, Mmus\Col16a1, Mmus\Tnn, Mmus\Col4a2, Mmus\Col14a1, Mmus\Col24a1, Mmus\4933412E24Rik, Mmus\Col7a1, Mmus\Col28a1, Mmus\Col25a1, Mmus\Col5a2, Mmus\Col4a5, Mmus\Col6a3, Mmus\Col5a3, Mmus\Col6a1, Mmus\Col5a1, Mmus\Col27a1, Mmus\Col4a3, Mmus\Col22a1, Mmus\Col9a1, Mmus\Col13a1, Mmus\Col4a1, Mmus\Col6a4, Mmus\8030474K03Rik, Mmus\Col11a2, Mmus\Vwa2, Mmus\Col4a4, Mmus\Col3a1, Mmus\Col4a6, Mmus\Col1a2, Mmus\Col6a6" "Hsap\COL5A1, Hsap\COL17A1, Hsap\COL6A3, Hsap\COL14A1, Hsap\COL4A2, Hsap\VWA1, Hsap\COL3A1, Hsap\COL11A2, Hsap\COL4A6, Hsap\COL23A1, Hsap\COLQ, Hsap\COL4A4, Hsap\COL6A6, Hsap\COL24A1, Hsap\COL9A1, Hsap\COL4A3, Hsap\COL2A1, Hsap\COL5A2, Hsap\COL11A1, Hsap\COL4A1, Hsap\COL27A1, Hsap\COL16A1, Hsap\VWA2, Hsap\COL9A3, Hsap\COL19A1, Hsap\COL25A1, Hsap\COL13A1, Hsap\COL9A2, Hsap\COL5A3, Hsap\COL4A5, Hsap\COL20A1, Hsap\COL6A1, Hsap\COL22A1, Hsap\COL6A5, Hsap\COL1A1, Hsap\COL7A1, Hsap\COL1A2" DRSC15012 IEK 1.640519945 0.86783679 1.981476138 -0.092427495 1.036820535 1.657364884 FBgn0034876 wmd wing morphogenesis defect http://flybase.org/reports/FBgn0034876 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "pter, CG3957, wmd, CG3957/wmd, WMD, Unrip" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR020472:G-protein beta WD-40 repeat" CG3957 11-Aug-17 DroID_v2017_08 Drer\strap Scer\TIF34 - Xtro\strap Mmus\Strap Hsap\STRAP "visible,dominant,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,viable" "wing,dorsal appendage,drug conditional,wing vein" FBgn0034459 CG16716 - http://flybase.org/reports/FBgn0034459 protein_coding_gene - cellular protein modification process ; GO:0006464 | inferred from electronic annotation with InterPro:IPR004344 - "anon-WO0140519.27, CG16716" IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase CG16716 11-Aug-17 DroID_v2017_08 "Drer\ttll11, Drer\ttll7, Drer\ttll6" - - "Xtro\ttll7, Xtro\ttll11" "Mmus\Kprp, Mmus\Ttll7, Mmus\Ttll6, Mmus\Ttll13, Mmus\Ttll11" "Hsap\KPRP, Hsap\NGRN, Hsap\TTLL11, Hsap\TTLL6, Hsap\TTLL7" viable FBgn0028931 CG16863 - http://flybase.org/reports/FBgn0028931 protein_coding_gene "RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001512074 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001512074" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001512074 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001512074 "DS00797.6, BG:DS00797.6, CG16863" "IPR013087:Zinc finger C2H2-type, IPR003656:Zinc finger, BED-type, IPR012337:Ribonuclease H-like domain" CG16863 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-93n13.2, Drer\si:ch211-152f22.4, Drer\mybl2a, Drer\LOC108179061, Drer\zbed4, Drer\si:dkey-13n23.3, Drer\zgc:161969, Drer\si:dkeyp-117b8.4, Drer\si:dkey-109j17.5" - "Cele\C53D6.6, Cele\ets-6, Cele\C10A4.1, Cele\ZK1098.2, Cele\bed-3, Cele\C09E7.4, Cele\F46F2.4, Cele\F19F10.11, Cele\ZK662.5, Cele\K09A11.1, Cele\dpy-20, Cele\gei-13" "Xtro\zbed1, Xtro\LOC105945140, Xtro\zbed4" "Mmus\Zbed4, Mmus\Zbed6" "Hsap\ZBED4, Hsap\ZBED1, Hsap\ZNF618, Hsap\DHRSX, Hsap\ZBED6, Hsap\ZBED6CL" viable FBgn0011706 rpr reaper http://flybase.org/reports/FBgn0011706 FBgn0045867 protein_coding_gene ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with Bruce ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Diap1 ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Diap2 protein homodimerization activity ; GO:0042803 | inferred from direct assay phospholipid binding ; GO:0005543 | inferred from direct assay larval midgut cell programmed cell death ; GO:0035096 | inferred from genetic interaction with hid apoptotic process ; GO:0006915 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity ; GO:2001056 | inferred from direct assay intrinsic apoptotic signaling pathway in response to osmotic stress ; GO:0008627 | traceable author statement programmed cell death ; GO:0012501 | traceable author statement larval central nervous system remodeling ; GO:0035193 | traceable author statement apoptotic process ; GO:0006915 | inferred from expression pattern inferred from mutant phenotype ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from expression pattern cellular response to ionizing radiation ; GO:0071479 | inferred from direct assay regulation of protein catabolic process ; GO:0042176 | inferred from direct assay nurse cell apoptotic process ; GO:0045476 | NOT traceable author statement apoptotic process ; GO:0006915 | inferred from direct assay apoptotic signaling pathway ; GO:0097190 | inferred from mutant phenotype apoptotic process ; GO:0006915 | traceable author statement intrinsic apoptotic signaling pathway in response to DNA damage ; GO:0008630 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:2001272 | inferred from direct assay imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from mutant phenotype positive regulation of protein ubiquitination ; GO:0031398 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from genetic interaction with hid negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype apoptotic signaling pathway ; GO:0097190 | inferred from genetic interaction with Diap1 programmed cell death ; GO:0012501 | inferred from mutant phenotype apoptotic process ; GO:0006915 | non-traceable author statement cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:2000060 | inferred from genetic interaction with eff cell death ; GO:0008219 | inferred from mutant phenotype proteasome complex ; GO:0000502 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial outer membrane ; GO:0005741 | inferred from direct assay "Rpr, rpr, RPR, CG4319, rp, anon-WO0162936.19, reaper, Reaper" - CG4319 11-Aug-17 DroID_v2017_08 - Scer\TEM1 "Cele\gip-1, Cele\let-756" - Mmus\Rin1 "Hsap\TSC1, Hsap\RIN1" " pupal stage , embryonic stage | stage 12 " " salivary gland

, organism | segmentally repeated

" "decreased cell death,increased cell death,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,visible,lethal,dominant,cell death defective,somatic clone,behavior defective,recessive,partially lethal - majority die,majority die during pupal stage,neuroanatomy defective,chemical sensitive,viable,small body,developmental rate defective,decreased cell number,decreased cell size,aging defective,long lived,female fertile,reduced,heat stress response defective,fertile,chemosensitive behavior defective,mating defective,locomotor behavior defective,conditional,sleep defective,lethal - all die before end of larval stage,some die during larval stage,feeding behavior defective,polyphasic,eclosion rhythm defective,lethal - all die before end of embryonic stage,some die during embryonic stage,drug conditional,flight defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,female,short lived,temperature conditional,size defective,majority die during pharate adult stage,locomotor rhythm defective,neurophysiology defective,courtship behavior defective,male,radiation resistant,cell non-autonomous,tetracycline conditional,cell autonomous" "eye,embryonic/larval salivary gland,heat sensitive,dMP2 neuron,MP1 neuron,wing,embryo,ommatidium,somatic clone,interommatidial bristle,eye disc,eye photoreceptor cell,peptidergic neuron | third instar larval stage,follicle cell,polar primary spermatocyte,corpus cardiacum,dorsomedial neurosecretory cell,oocyte,neurosecretory neuron,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial ligament cell & stage 16 embryorepo,lch5 ligament attachment cell | embryonic stage 16,lipid droplet & larval fat bodysal.BO,embryonic/larval oenocyte,neuron,adult head,pharate adult,leg,subesophageal ganglion neuron,thoracico-abdominal ganglion,embryonic/larval midgut,adult midgut precursor cell,alula,axillary cell,adult brain,wing disc | third instar larval stage,head | pharate adult stage,plasmatocyte | third instar larval stage,embryonic/larval lymph gland | first instar larval stage,adult dorsal vessel,embryonic cardioblast | embryonic stage 15,embryonic/larval salivary gland | embryonic stage 17,amnioserosa,nurse cell,follicle cell & nucleus | somatic clone,nurse cell & nucleus | somatic clone,nurse cell ring canal,nurse cell & cytoskeleton | somatic clone,macrochaeta & scutellum-537.4,macrochaeta & mesothoracic tergum-537.4,macrochaeta & tergum-537.4,border follicle cell,larval hindgut & ectoderm455.2,hindgut visceral muscle primordium,U neuron,pCC neuron,RP2 motor neuron,aCC neuron,wing vein,ectopic,wing vein L2,wing vein L4,wing vein L5,large sensillum basiconicum of antennal segment 3 & olfactory neuronOr22a.8197,large sensillum basiconicum of antennal segment 3 & olfactory neuronOr22b.10287,olfactory neuron & maxillary palp sense organOr42a.PG,olfactory neuron & maxillary palp sense organOr71a.PG,olfactory neuron & maxillary palp sense organ,olfactory neuron & maxillary palp sense organOr33c.PG,olfactory neuron & maxillary palp sense organOr46a.PG,olfactory sensory organ,sensillum basiconicum of antennal segment 3,maxillary palp sensillum basiconicum,eo dendrite & sensillum basiconicum of antennal segment 3Obp28a.PP,abdominal dorsal/lateral multidendritic neuron,neuron | larval stage,LNv neuron,Pdf neuron,ventral midline | embryonic stage,midline glial cell,centripetally migrating follicle cell,photoreceptor cell R5,embryonic/larval trachea,dorsal,adult cuticle,EH neurosecretory neuron,embryonic/larval mouth,Tv neuron,outer photoreceptor cell,macrochaeta,neuropil glial sheath | late embryonic stage,embryonic/larval brain | late embryonic stage,glial cell | larval stage,wing disc,rhabdomere R7,tetracycline conditional,male genitalia,conditional,retina,cell autonomous" DRSC11390 IE 1.826927148 0.763723667 1.806261988 -1.144980326 -0.072482058 0.22588269 FBgn0028978 trbl tribbles http://flybase.org/reports/FBgn0028978 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with trbl protein serine/threonine kinase activity ; GO:0004674 | NOT traceable author statement mitogen-activated protein kinase kinase binding ; GO:0031434 | inferred from biological aspect of ancestor with PANTHER:PTN001121144 protein kinase activity ; GO:0004672 | NOT inferred from sequence or structural similarity with HGNC:16228 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with slbo ventral furrow formation ; GO:0007370 | inferred from genetic interaction with stg positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from biological aspect of ancestor with PANTHER:PTN001121144 negative regulation of mitotic nuclear division ; GO:0045839 | inferred from mutant phenotype inferred from genetic interaction with stg regulation of MAP kinase activity ; GO:0043405 | inferred from biological aspect of ancestor with PANTHER:PTN001121144 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:2000060 | inferred from direct assay negative regulation of insulin receptor signaling pathway ; GO:0046627 | inferred from genetic interaction with Pi3K92E inferred from genetic interaction with Pten regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype gastrulation ; GO:0007369 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay "trbl, CG5408, trb, Trbl" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR024104:Pseudokinase tribbles family/serine-threonine-protein kinase 40" CG5408 11-Aug-17 DroID_v2017_08 "Drer\trib2, Drer\stk40, Drer\trib1, Drer\trib3" - "Cele\par-4, Cele\F32D8.1, Cele\nipi-3" "Xtro\trib1, Xtro\trib2, Xtro\stk40" "Mmus\Trib1, Mmus\Stk40, Mmus\Trib3, Mmus\Trib2" "Hsap\TRIB1, Hsap\TRIB3, Hsap\TRIB2, Hsap\STK40" "partially lethal - majority die,lethal,partially lethal,visible,partially lethal - majority live,partially,recessive,mitotic cell cycle defective,wild-type,memory defective,polyphasic,female sterile,increased cell size,decreased cell number,viable" "ovary,border follicle cell,crossvein,wing,posterior compartment,macrochaeta,oocyte,cystocyte,mitotic domain 1,mitotic domain 2,mitotic domain 3,gastrula embryo,mesoderm anlage,trichogen cell,tormogen cell,mitotic domain 10,ventral furrow,mitotic cell cycle[-],spermatogonium,germline cyst,ectopic,egg chamber,mitotic cell cycle,eye,interommatidial bristle,wing margin,wing disc,external sensory organ precursor cell I,nurse cell,spermatogonial cyst" DRSC11901 K -0.332280978 -0.16868384 0.501439725 0.07404055 0.358122048 -2.302610888 FBgn0000237 bul bulge http://flybase.org/reports/FBgn0000237 - gene molecular_function ; GO:0003674 | no biological data available compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with aos cellular_component ; GO:0005575 | no biological data available "bp, bul" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,recessive,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,male fertile,female semi-sterile,lethal,dominant,female fertile,flightless" "ommatidium,wing,embryonic/larval glial cell,lens,pigment cell,eye & macrochaeta,eye" FBgn0001748 l(1)HM20 lethal (1) HM20 http://flybase.org/reports/FBgn0001748 - gene - - - l(1)HM20 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,cold sensitive,female sterile,visible" "macrochaeta,adult abdomen" FBgn0034528 CG11180 - http://flybase.org/reports/FBgn0034528 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467 neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG11180 IPR000467:G-patch domain CG11180 11-Aug-17 DroID_v2017_08 Drer\pinx1 Scer\PXR1 Cele\T23G7.3 "Xtro\iws1, Xtro\pinx1" "Mmus\Gpatch4, Mmus\Pinx1" "Hsap\ZNF804A, Hsap\GPATCH8, Hsap\PINX1, Hsap\ZNF804B" "lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0010927 l(3)08126 lethal (3) 08126 http://flybase.org/reports/FBgn0010927 FBgn0011325 gene - - - "l(3)j2B3, l(3)08126" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0069176 mcl(2)Z4579 mcl(2)Z4579 http://flybase.org/reports/FBgn0069176 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z4579 - - 11-Aug-17 DroID_v2017_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0030121 Cfp1 CXXC finger protein 1 http://flybase.org/reports/FBgn0030121 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002857 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965, InterPro:IPR002857" histone H3-K4 methylation ; GO:0051568 | inferred from direct assay Set1C/COMPASS complex ; GO:0048188 | inferred from direct assay "CG17446, Cfp1, dCfp1, dCXXC1, CXXC1" "IPR001965:Zinc finger, PHD-type, IPR002857:Zinc finger, CXXC-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR022056:CpG binding protein, C-terminal, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17446 11-Aug-17 DroID_v2017_08 "Drer\cxxc1b, Drer\cxxc1a, Drer\bptf" Scer\SPP1 Cele\cfp-1 "Xtro\bptf, Xtro\cxxc1" "Mmus\Cxxc1, Mmus\Dido1, Mmus\Bptf" "Hsap\CXXC1, Hsap\DIDO1, Hsap\BPTF" "viable,partially lethal - majority die,some die during pupal stage" FBgn0011031 l(3)s2564 lethal (3) s2564 http://flybase.org/reports/FBgn0011031 - gene - - - l(3)s2564 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001463 l(1)7Ed lethal (1) 7Ed http://flybase.org/reports/FBgn0001463 - gene - - - l(1)7Ed - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0260991 Incenp Inner centromere protein http://flybase.org/reports/FBgn0260991 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with aurB microtubule binding ; GO:0008017 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype histone phosphorylation ; GO:0016572 | inferred from mutant phenotype meiotic chromosome condensation ; GO:0010032 | inferred from mutant phenotype spindle assembly involved in female meiosis ; GO:0007056 | inferred from mutant phenotype meiotic spindle midzone assembly ; GO:0051257 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype metaphase plate congression ; GO:0051310 | inferred from mutant phenotype male meiosis sister chromatid cohesion ; GO:0007065 | inferred from mutant phenotype "chromosome passenger complex ; GO:0032133 | inferred from direct assay midbody ; GO:0030496 | colocalizes_with inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay mitotic spindle midzone ; GO:1990023 | colocalizes_with inferred from direct assay meiotic spindle midzone ; GO:1990385 | colocalizes_with inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay condensed chromosome ; GO:0000793 | colocalizes_with inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay" "Incenp, incenp, INCENP, dIncenp, CG12165, DmINCENP, anon-WO0118547.171, mat(2)earlyQA26, mat(2)ea-C" "IPR005635:Inner centromere protein, ARK-binding domain" CG12165 11-Aug-17 DroID_v2017_08 "Drer\sb:cb986, Drer\map7d3" - Cele\icp-1 Xtro\incenp Mmus\Incenp Hsap\INCENP FBgn0005431 l(1)10Ea lethal (1) 10Ea http://flybase.org/reports/FBgn0005431 "FBgn0001506, FBgn0001864" gene - - - l(1)10Ea - - 11-Aug-17 DroID_v2017_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0002705 meg megaoculus http://flybase.org/reports/FBgn0002705 - gene - - - meg - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,male sterile,recessive,female sterile,visible" "eye,wing,wing vein" FBgn0039704 neo neyo http://flybase.org/reports/FBgn0039704 protein_coding_gene - regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype apical constriction ; GO:0003383 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model "neo, CG7802" "IPR001507:Zona pellucida domain, IPR003609:PAN/Apple domain" CG7802 11-Aug-17 DroID_v2017_08 - - "Cele\F32B4.8, Cele\ZC449.2, Cele\H42K12.3, Cele\C34C12.7, Cele\noah-2, Cele\cutl-28, Cele\C16D9.1, Cele\F52C9.5, Cele\cutl-17, Cele\H03E18.1, Cele\T26C5.2, Cele\let-653, Cele\cutl-27, Cele\T23F1.5, Cele\noah-1, Cele\cutl-18, Cele\R07A4.4, Cele\ZC449.1" - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0031639 mRpS2 mitochondrial ribosomal protein S2 http://flybase.org/reports/FBgn0031639 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82923 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y399 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:P82923 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y399 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82923 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y399 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "mRpS2, CG2937, MRP-S2" "IPR001865:Ribosomal protein S2, IPR005706:Ribosomal protein S2, bacteria/mitochondria/plastid, IPR023591:Ribosomal protein S2, flavodoxin-like domain" CG2937 11-Aug-17 DroID_v2017_08 "Drer\nup37, Drer\mrps2" Scer\MRP4 Cele\mrps-2 "Xtro\nup37, Xtro\mrps2" "Mmus\Mrps2, Mmus\Nup37" Hsap\MRPS2 "viable,fertile,visible" trichogen cell FBgn0033054 CG14591 - http://flybase.org/reports/FBgn0033054 protein_coding_gene - - - CG14591 IPR026508:Transmembrane protein 164 CG14591 11-Aug-17 DroID_v2017_08 Drer\tmem164 - Cele\C35C5.10 Xtro\tmem164 Mmus\Tmem164 Hsap\TMEM164 viable FBgn0037440 CRAT Carnitine O-Acetyl-Transferase http://flybase.org/reports/FBgn0037440 protein_coding_gene carnitine O-acetyltransferase activity ; GO:0004092 | inferred from sequence or structural similarity with HGNC:2342 fatty acid beta-oxidation ; GO:0006635 | non-traceable author statement nucleoplasm ; GO:0005654 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:2342 inferred from sequence model inferred from direct assay "CG1041, CRAT" IPR000542:Acyltransferase ChoActase/COT/CPT CG1041 11-Aug-17 DroID_v2017_08 "Drer\cpt1aa, Drer\crata, Drer\chata, Drer\crot, Drer\cpt1cb, Drer\cpt1b, Drer\zgc:154046, Drer\cpt1ab, Drer\cratb, Drer\LOC101884918, Drer\si:ch211-256m1.8" Scer\CAT2 "Cele\cha-1, Cele\W03F9.4, Cele\B0395.3" "Xtro\crat.2, Xtro\crat.1, Xtro\chat, Xtro\cpt1b, Xtro\LOC100490391" "Mmus\Crot, Mmus\Cpt1c, Mmus\Cpt1b, Mmus\Chat, Mmus\Crat, Mmus\Cpt1a" "Hsap\CRAT, Hsap\CPT1B, Hsap\CPT1C, Hsap\CPT1A, Hsap\CROT, Hsap\CHAT" "viable,fertile" FBgn0020407 asun asunder http://flybase.org/reports/FBgn0020407 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of fertilization ; GO:0080154 | inferred from mutant phenotype centrosome localization ; GO:0051642 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype snRNA 3'-end processing ; GO:0034472 | inferred from direct assay flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype oocyte nucleus localization involved in oocyte dorsal/ventral axis specification ; GO:0051663 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay integrator complex ; GO:0032039 | inferred from direct assay "CG6814, asun, Mat89Bb, IntS13, ASUN, Asu" IPR019355:Cell cycle regulator Mat89Bb CG6814 11-Aug-17 DroID_v2017_08 Drer\asun - Cele\R02D3.4 Xtro\asun Mmus\Asun Hsap\ASUN " adult stage , adult stage && oogenesis stage | stage S10 , adult stage && oogenesis stage | stage S9-10 , embryonic stage | 0-4 hr , adult stage && oogenesis stage | stage >=S10 " " testis

, follicle cell

, ovary

, nurse cell

, oocyte

" "male sterile,meiotic cell cycle defective,viable" "centrosome, with bor+t4,spermatocyte,spermatid,egg,dorsal appendage,maternal effect,egg chamber,ovary,micropyle | maternal effect,oocyte nucleus,centrosome,spermatozoon,onion stage spermatid,primary spermatocyte,aster & primary spermatocyte in meiotic prophase I,spindle & spermatocyte,nucleus & elongation stage spermatid,microtubule basal body & elongation stage spermatid,investment cone,nucleus & unfertilized egg,nucleus | blastoderm stage" FBgn0031589 CG3714 - http://flybase.org/reports/FBgn0031589 protein_coding_gene nicotinate-nucleotide diphosphorylase (carboxylating) activity ; GO:0004514 | inferred from electronic annotation with InterPro:IPR002638 nicotinate phosphoribosyltransferase activity ; GO:0004516 | inferred from sequence or structural similarity with UniProtKB:Q6XQN6 NAD biosynthetic process ; GO:0009435 | inferred from electronic annotation with InterPro:IPR002638 nicotinate nucleotide salvage ; GO:0019358 | inferred from electronic annotation with InterPro:IPR006405 response to oxidative stress ; GO:0006979 | inferred from sequence or structural similarity with UniProtKB:Q6XQN6 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:Q6XQN6 "AAF51037, CG3714" "IPR006405:Nicotinate phosphoribosyltransferase pncB-type, IPR007229:Nicotinate phosphoribosyltransferase family, IPR002638:Quinolinate phosphoribosyl transferase, C-terminal" CG3714 11-Aug-17 DroID_v2017_08 Drer\naprt Scer\NPT1 Cele\nprt-1 Xtro\naprt Mmus\Naprt Hsap\NAPRT "partially lethal - majority die,some die during pupal stage" FBgn0036118 Blos2 "Biogenesis of lysosome-related organelles complex 1, subunit 2" http://flybase.org/reports/FBgn0036118 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Snapin protein homodimerization activity ; GO:0042803 | inferred from direct assay biological_process ; GO:0008150 | no biological data available BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:20984 "CG14145, DmBlos2, BLOS2, NP_648427, Blos2, blos2" "IPR019269:Biogenesis of lysosome-related organelles complex-1, subunit 2" CG14145 11-Aug-17 DroID_v2017_08 Drer\bloc1s2 - "Cele\Y73B6BL.289, Cele\blos-2" Xtro\bloc1s2 Mmus\Bloc1s2 Hsap\BLOC1S2 FBgn0040823 dpr6 defective proboscis extension response 6 http://flybase.org/reports/FBgn0040823 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 neuron projection membrane ; GO:0032589 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "CG14162, Dpr-6, BcDNA:LD13525, dpr6, Dpr6" "IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR013106:Immunoglobulin V-set domain, IPR003599:Immunoglobulin subtype" CG14162 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-264f5.6, Drer\LOC101885725, Drer\si:dkey-65b12.12, Drer\si:ch211-163c2.2, Drer\ntm, Drer\LOC100333196, Drer\LOC101885444" - Cele\zig-8 "Xtro\nfasc, Xtro\obsl1" Mmus\Amica1 "Hsap\CADM3, Hsap\LSAMP, Hsap\CADM4, Hsap\CADM2, Hsap\CADM1" viable DRSC09005 IEK -2.103560721 -3.468354635 -0.894535706 2.520202704 0.908188822 1.858861151 FBgn0038471 CG5220 - http://flybase.org/reports/FBgn0038471 protein_coding_gene tRNA methyltransferase activity ; GO:0008175 | inferred from electronic annotation with InterPro:IPR028590 RNA methylation ; GO:0001510 | inferred from electronic annotation with InterPro:IPR015507 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR028590 - "CG5220, Dm TRM7" "IPR002877:Ribosomal RNA methyltransferase FtsJ domain, IPR015507:Ribosomal RNA large subunit methyltransferase E, IPR028590:tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG5220 11-Aug-17 DroID_v2017_08 Drer\ftsj1 "Scer\TRM7, Scer\MRM2" "Cele\R74.7, Cele\Y40D12A.1" Xtro\ftsj1 Mmus\Ftsj1 "Hsap\MRM2, Hsap\FTSJ1" viable FBgn0039182 CG5728 - http://flybase.org/reports/FBgn0039182 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN001149535 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN001149535 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN001149535 CG5728 "IPR003029:S1 domain, IPR011990:Tetratricopeptide-like helical domain, IPR003107:HAT (Half-A-TPR) repeat, IPR008847:Suppressor of forked, IPR012340:Nucleic acid-binding, OB-fold, IPR022967:RNA-binding domain, S1" CG5728 11-Aug-17 DroID_v2017_08 Drer\pdcd11 Scer\RRP5 Cele\let-716 Xtro\pdcd11 Mmus\Pdcd11 Hsap\PDCD11 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0015756 RpL9 Ribosomal protein L9 http://flybase.org/reports/FBgn0015756 "FBgn0025200, FBgn0045928, FBgn0045929, FBgn0045930" protein_coding_gene "rRNA binding ; GO:0019843 | inferred from electronic annotation with InterPro:IPR000702, InterPro:IPR020040 structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000183645" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000702, InterPro:IPR002359, InterPro:IPR020040 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "L9, rpL9, M(2)32D, anon-EST:fe3A6, CG6141, anon-WO0153538.27, anon-WO0153538.26, anon-WO0153538.25, RpL9, Rpl9, Rp L9" "IPR000702:Ribosomal protein L6, IPR002359:Ribosomal protein L6, conserved site-2, IPR020040:Ribosomal protein L6, alpha-beta domain" CG6141 11-Aug-17 DroID_v2017_08 Drer\rpl9 "Scer\RPL9A, Scer\RPL9B" Cele\rpl-9 Xtro\rpl9 Mmus\Rpl9 Hsap\RPL9 embryonic stage -- adult stage "Minute,lethal,recessive,visible,dominant,wild-type,lethal - all die before end of pupal stage,some die during pupal stage" "macrochaeta,eye" DRSC03418 IEK -2.951546704 -1.747894895 0.733815849 -2.856036494 1.471229505 3.532773375 FBgn0031995 CG8475 - http://flybase.org/reports/FBgn0031995 protein_coding_gene calmodulin binding ; GO:0005516 | inferred from electronic annotation with InterPro:IPR008734 phosphorylase kinase activity ; GO:0004689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000844181 glycogen metabolic process ; GO:0005977 | inferred from electronic annotation with InterPro:IPR008734 phosphorylase kinase complex ; GO:0005964 | inferred from biological aspect of ancestor with PANTHER:PTN000844181 CG8475 "IPR008734:Phosphorylase kinase alpha/beta subunit, IPR008928:Six-hairpin glycosidase-like, IPR011613:Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family" CG8475 11-Aug-17 DroID_v2017_08 "Drer\phka1b, Drer\phka2, Drer\phka1a, Drer\phkb" - Cele\Y67D8A.2 "Xtro\LOC100498239, Xtro\phka2, Xtro\phkb" "Mmus\Phka2, Mmus\Phkb, Mmus\Phka1" "Hsap\PHKA2, Hsap\PHKB, Hsap\PHKA1" viable FBgn0032713 CG17323 - http://flybase.org/reports/FBgn0032713 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CT35071, CG17323" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG17323 11-Aug-17 DroID_v2017_08 "Drer\ugt2a6, Drer\ugt2a2, Drer\ugt1b3, Drer\zgc:172315, Drer\ugt5a2, Drer\ugt5c1, Drer\ugt5e1, Drer\ugt5b6, Drer\ugt1b2, Drer\ugt5a5, Drer\ugt2b6, Drer\ugt1b5, Drer\ugt5c3, Drer\ugt2b3, Drer\ugt1b4, Drer\ugt5f1, Drer\ugt2a5, Drer\ugt5b2, Drer\ugt8, Drer\ugt5g2, Drer\ugt5a1, Drer\ugt2b5, Drer\ugt5c2, Drer\ugt1ab, Drer\ugt5b3, Drer\ugt5g1, Drer\ugt5b1, Drer\ugt5d1, Drer\ugt1b7, Drer\ugt2b1, Drer\ugt5a4" Scer\ATG26 "Cele\ugt-35, Cele\ugt-61, Cele\ugt-44, Cele\ugt-54, Cele\ugt-46, Cele\ugt-11, Cele\ugt-57, Cele\ugt-24, Cele\ugt-33, Cele\H23N18.4, Cele\ugt-26, Cele\ugt-7, Cele\C55H1.1, Cele\ugt-62, Cele\C03A7.12, Cele\ugt-49, Cele\ugt-56, Cele\ugt-55, Cele\ugt-52, Cele\ugt-50, Cele\ugt-15, Cele\ugt-12, Cele\ugt-34, Cele\ugt-47, Cele\ugt-20, Cele\ugt-9, Cele\ugt-58, Cele\ugt-22, Cele\ugt-16, Cele\ugt-18, Cele\ugt-5, Cele\ugt-38, Cele\ugt-4, Cele\ugt-43, Cele\ugt-37, Cele\ugt-59, Cele\ugt-36, Cele\ugt-60, Cele\ugt-28, Cele\ugt-30, Cele\ugt-32, Cele\ugt-41, Cele\ugt-53, Cele\ugt-19, Cele\ugt-25, Cele\C23G10.6, Cele\ugt-1, Cele\ugt-39, Cele\ugt-14, Cele\ugt-51, Cele\ugt-45, Cele\ugt-6, Cele\ugt-10, Cele\ugt-8, Cele\ugt-40, Cele\F54C1.1, Cele\ugt-21, Cele\ugt-42, Cele\ugt-27, Cele\ugt-31, Cele\ugt-2, Cele\ugt-48, Cele\ugt-29, Cele\C03A7.13, Cele\K04A8.10, Cele\ugt-23, Cele\F10D2.8, Cele\ugt-17, Cele\ugt-3, Cele\ugt-13, Cele\Y43D4A.2" "Xtro\ugt8, Xtro\ugt2b4, Xtro\ugt2a1, Xtro\ugt1a6, Xtro\ugt3a2" "Mmus\Ugt2b36, Mmus\Ugt2b34, Mmus\Ugt2a3, Mmus\Ugt8a, Mmus\Ugt2b37, Mmus\Ugt1a7c, Mmus\Ugt2b35, Mmus\Ugt1a2, Mmus\Ugt3a1, Mmus\Ugt1a1, Mmus\Ugt1a6b, Mmus\Ugt2b1, Mmus\Ugt2b38, Mmus\Ugt1a9, Mmus\Ugt3a2, Mmus\Ugt1a5, Mmus\Ugt2b5, Mmus\Ugt2a1" "Hsap\UGT1A9, Hsap\UGT1A7, Hsap\UGT3A1, Hsap\UGT1A1, Hsap\UGT8, Hsap\UGT2A2, Hsap\UGT3A2, Hsap\UGT1A4, Hsap\UGT2B17, Hsap\UGT2B10, Hsap\UGT2B15, Hsap\UGT2B28, Hsap\UGT1A5, Hsap\UGT1A10, Hsap\UGT2B11, Hsap\UGT2B7, Hsap\UGT1A8, Hsap\UGT2A3, Hsap\UGT1A6, Hsap\UGT2B4, Hsap\UGT1A3" pupal stage salivary gland

"behavior defective,recessive,viable" FBgn0045842 yuri yuri gagarin http://flybase.org/reports/FBgn0045842 protein_coding_gene - ciliary basal body organization ; GO:0032053 | inferred from direct assay sperm individualization ; GO:0007291 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay sarcoplasmic reticulum ; GO:0016529 | colocalizes_with inferred from direct assay investment cone ; GO:0070865 | inferred from direct assay "CG31732, CG11860, BG:DS05639.1, CG12635, BG:DS07851.11, yuri, Yuri" IPR031843:Yuri gagarin CG31732 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-1a11.3 - Cele\rfip-1 - - - "viable,fertile,auditory perception defective,gravitaxis defective,sterile,male limited" "spermatozoon,spermatid cyst,spermatid,investment cone,ciliary basal body,filamentous actin" FBgn0039213 atl atlastin http://flybase.org/reports/FBgn0039213 protein_coding_gene GTPase activity ; GO:0003924 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8I0P1 GTPase activity ; GO:0003924 | inferred from mutant phenotype protein homodimerization activity ; GO:0042803 | inferred from mutant phenotype GTP binding ; GO:0005525 | inferred from mutant phenotype identical protein binding ; GO:0042802 | inferred from direct assay guanyl ribonucleotide binding ; GO:0032561 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype endoplasmic reticulum membrane fusion ; GO:0016320 | inferred from direct assay inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype regulation of microtubule depolymerization ; GO:0031114 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype microtubule depolymerization ; GO:0007019 | inferred from mutant phenotype membrane fusion ; GO:0061025 | inferred from direct assay neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype protein homooligomerization ; GO:0051260 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay intrinsic component of endoplasmic reticulum membrane ; GO:0031227 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay microtubule ; GO:0005874 | colocalizes_with inferred from direct assay membrane ; GO:0016020 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG6668, atl, ATL, Atl" "IPR015894:Guanylate-binding protein, N-terminal, IPR030386:GB1/RHD3-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003191:Guanylate-binding protein, C-terminal" CG6668 11-Aug-17 DroID_v2017_08 "Drer\gbp4, Drer\unm_sa911, Drer\zgc:158270, Drer\gbp2, Drer\LOC100535674, Drer\gbp1, Drer\si:ch211-209n20.1, Drer\LOC100149641, Drer\atl3, Drer\atl2, Drer\atl1" - "Cele\atln-1, Cele\atln-2" "Xtro\atl3, Xtro\gbp5, Xtro\gbp7, Xtro\rnf112.1, Xtro\rnf112, Xtro\atl2, Xtro\gbp1, Xtro\gbp6, Xtro\gbp4, Xtro\atl1" "Mmus\Gbp2, Mmus\Gbp3, Mmus\Rnf112, Mmus\Atl1, Mmus\Gbp8, Mmus\Atl3, Mmus\Gbp4, Mmus\Atl2, Mmus\Gbp7, Mmus\Gbp5, Mmus\Gbp2b, Mmus\Gbp6, Mmus\Gbp9, Mmus\Gbp10" "Hsap\GBP7, Hsap\GBP2, Hsap\RNF112, Hsap\GBP1, Hsap\ATL3, Hsap\GBP5, Hsap\GBP4, Hsap\GBP6, Hsap\GBP3, Hsap\ATL2, Hsap\ATL1" "neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,small body,recessive,sterile,viable,fertile,bang sensitive,short lived,locomotor behavior defective,lethal" "NMJ bouton,abdominal 2 ventral longitudinal muscle 3,abdominal 2 ventral longitudinal muscle 4,postsynaptic membraneExel7357),microtubule & embryonic/larval somatic muscleExel7357),imaginal disc,somatic clone,oocyte,dopaminergic neuron,endoplasmic reticulum,microtubule & embryonic/larval somatic muscleC57,embryonic/larval somatic muscle,endoplasmic reticulum‘±Tub84B.PL,endoplasmic reticulumD42" FBgn0023441 fus fusilli http://flybase.org/reports/FBgn0023441 "FBgn0015696, FBgn0034034" protein_coding_gene mRNA binding ; GO:0003729 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with cact inferred from genetic interaction with Egfr regulation of RNA splicing ; GO:0043484 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P35637 "CG8205, cg8205, E(cact[E10])7, fus" "IPR000504:RNA recognition motif domain, IPR012337:Ribonuclease H-like domain" CG8205 11-Aug-17 DroID_v2017_08 "Drer\hnrnph1, Drer\esrp2, Drer\esrp1, Drer\hnrnph1l, Drer\hnrnph3" - "Cele\sym-2, Cele\hrpf-2" "Xtro\hnrnph1, Xtro\esrp1, Xtro\hnrnph3" "Mmus\Hnrnph1, Mmus\Esrp2, Mmus\Hnrnph2, Mmus\Hnrnpf, Mmus\Hnrnph3, Mmus\Esrp1" "Hsap\HNRNPF, Hsap\ESRP2, Hsap\ESRP1, Hsap\HNRNPH3, Hsap\HNRNPH2, Hsap\HNRNPH1" " adult stage && oogenesis stage , embryonic stage | stage 9 , embryonic stage | stage 13 , embryonic stage | stage 11 " " follicle cell

, proctodeum

, stomodeum

, embryonic/larval posterior spiracle

, ectoderm

segmentally repeated , embryonic/larval fat body

, nurse cell

, embryonic foregut

, mesoderm

segmentally repeated " "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,body color defective,partially lethal - majority die,some die during pupal stage" "wing,posterior compartment,mesothoracic tergum" FBgn0001782 l(1)M75 lethal (1) M75 http://flybase.org/reports/FBgn0001782 - gene - - - l(1)M75 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0051297 CG31297 - http://flybase.org/reports/FBgn0051297 protein_coding_gene - - - CG31297 - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0039016 Dcr-1 Dicer-1 http://flybase.org/reports/FBgn0039016 protein_coding_gene single-stranded RNA binding ; GO:0003727 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with piwi inferred from physical interaction with vas protein binding ; GO:0005515 | inferred from physical interaction with loqs double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NFU0 protein binding ; GO:0005515 | inferred from physical interaction with AGO1 bidentate ribonuclease III activity ; GO:0016443 | inferred from direct assay pre-miRNA binding ; GO:0070883 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with AGO2 "RNA interference ; GO:0016246 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype production of miRNAs involved in gene silencing by miRNA ; GO:0035196 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype pre-miRNA processing ; GO:0031054 | inferred from direct assay mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype pre-miRNA processing ; GO:0031054 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from direct assay siRNA loading onto RISC involved in RNA interference ; GO:0035087 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype pre-miRNA processing ; GO:0031054 | traceable author statement RNA interference ; GO:0016246 | inferred from direct assay germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from genetic interaction with AGO1 response to starvation ; GO:0042594 | inferred from mutant phenotype germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay RISC complex ; GO:0016442 | inferred from direct assay "Dcr-1, dcr-1, dicer-1, CG4792, Dicer, dicer, DCR1, dicer1, Dicer1, dcr1, DICER, cg4792, Dcr1, DCR-1, dcr 1, Dcr, Dicer-1, dmDcr1" "IPR000999:Ribonuclease III domain, IPR001650:Helicase, C-terminal, IPR003100:PAZ domain, IPR005034:Dicer dimerisation domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014720:Double-stranded RNA-binding domain" CG4792 11-Aug-17 DroID_v2017_08 "Drer\dhx58, Drer\dicer1" "Scer\IRC3, Scer\MPH1" "Cele\drh-3, Cele\drh-1, Cele\dcr-1" Xtro\dicer1 "Mmus\Fancm, Mmus\Dicer1, Mmus\Dhx58" "Hsap\DICER1, Hsap\DHX58, Hsap\FANCM" "lethal - all die before end of P-stage,some die during pharate adult stage,neurophysiology defective,somatic clone,neuroanatomy defective,decreased cell growth,visible,lethal,recessive,lethal - all die during embryonic stage,decreased cell number,mitotic cell cycle defective,increased cell death,hypoplasia,somatic clone - Minute background,lethal - all die before end of embryonic stage,some die during embryonic stage,suppressor of variegation,size defective,partially lethal - majority die,viable" "oocyte,germline clone,ovariole,germline stem cell,dendrite | somatic clone,abdominal 1 dorsal multidendritic neuron ddaC,somatic clone,wing disc,eye,dendrite & ad PN | somatic clone,dendrite & lPN | somatic clone,dendrite & vPN | somatic clone,dendrite & DL1 adPN | somatic clone,dendrite & DA1 lPN | somatic clone,axon & DL1 adPN | somatic clone,antennal lobe projection neuron adPN,adult antennal lobe projection neuron DL1 adPN,antennal lobe projection neuron lPN,mushroom body,alpha/beta Kenyon cell,alpha'/beta' Kenyon cell,pole cell,maternal effect,wing,chaeta & mesothoracic tergum | somatic clone,eye disc,female germline stem cell,wing margin bristle,somatic clone - Minute background,wing blade,wing disc | third instar larval stage,embryonic/larval neuromuscular junction" FBgn0033159 Dscam1 Down syndrome cell adhesion molecule 1 http://flybase.org/reports/FBgn0033159 protein_coding_gene identical protein binding ; GO:0042802 | inferred from physical interaction with Dscam1 antigen binding ; GO:0003823 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Dscam1 axon guidance receptor activity ; GO:0008046 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from electronic annotation with InterPro:IPR032983 cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR033027 positive regulation of myoblast differentiation ; GO:0045663 | inferred from electronic annotation with InterPro:IPR032983 embryonic morphogenesis ; GO:0048598 | inferred from electronic annotation with InterPro:IPR032983 regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype detection of molecule of bacterial origin ; GO:0032490 | inferred from direct assay axon guidance ; GO:0007411 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype dendrite self-avoidance ; GO:0070593 | inferred from mutant phenotype central nervous system morphogenesis ; GO:0021551 | inferred from mutant phenotype axon extension involved in axon guidance ; GO:0048846 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from genetic interaction with Abl peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype dendrite self-avoidance ; GO:0070593 | inferred from direct assay axon guidance ; GO:0007411 | traceable author statement detection of mechanical stimulus involved in sensory perception of touch ; GO:0050976 | inferred from genetic interaction with Fmr1 regulation of axonogenesis ; GO:0050770 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from genetic interaction with TBCD axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with dock axonal fasciculation ; GO:0007413 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with Fmr1 "integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR032983, InterPro:IPR033027 dendrite ; GO:0030425 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence model neuronal cell body ; GO:0043025 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay neuron projection ; GO:0043005 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity" "FBgn0033159, Neu1, Dscam1, p270, CT39257, l(2)43Bc, 43Bc, l(2)05518, CG17800, dscam1, DScam, Dscam, DSCAM, dscam, dScam, Dm_2R:13612, DmDscam, DsCam, Dsm, Dscam-hv, Dm_2R:13579" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR033027:Down syndrome cell adhesion molecule, IPR032983:Cell adhesion molecule-related/down-regulated by oncogenes, IPR021012:Down syndrome cell adhesion molecule, C-terminal, IPR013098:Immunoglobulin I-set" CG17800 11-Aug-17 DroID_v2017_08 "Drer\mylka, Drer\dscamb, Drer\osmr, Drer\mylk4a, Drer\il6st, Drer\lifrb, Drer\mylkb, Drer\mylk4b, Drer\il12rb2l, Drer\dscaml1, Drer\mylk3, Drer\ptprma, Drer\il12rb2, Drer\dscama, Drer\tek, Drer\ptprub, Drer\csf3r" - "Cele\egl-15, Cele\ZC373.4, Cele\him-4, Cele\sax-7, Cele\unc-89" "Xtro\ptpru, Xtro\dscam, Xtro\mylk, Xtro\ptprm, Xtro\il6st, Xtro\mylk3, Xtro\osmr, Xtro\dscaml1, Xtro\lifr, Xtro\csf3r, Xtro\mylk4" "Mmus\Ptprm, Mmus\Il31ra, Mmus\Dscaml1, Mmus\Vsig10, Mmus\Il27ra, Mmus\Tek, Mmus\Lifr, Mmus\Mylk, Mmus\Tie1, Mmus\Il6st, Mmus\Mylk4, Mmus\Il12rb2, Mmus\Osmr, Mmus\Mylk2, Mmus\Csf3r, Mmus\Lepr, Mmus\Mylk3, Mmus\Ptprk, Mmus\Dscam, Mmus\Ptpru" "Hsap\PTPRU, Hsap\MYLK4, Hsap\PTPRM, Hsap\DSCAML1, Hsap\IL12RB2, Hsap\IL31RA, Hsap\CSF3R, Hsap\LEPR, Hsap\MYLK2, Hsap\TEK, Hsap\VSIG10, Hsap\LIFR, Hsap\OSMR, Hsap\MYLK, Hsap\HSPG2, Hsap\IL6ST, Hsap\PTPRK, Hsap\DSCAM, Hsap\PTPRT, Hsap\MYLK3" embryonic stage | stage 5 ventral neurogenic region | restricted

"neuroanatomy defective,somatic clone,viable,lethal,recessive,wild-type,fertile,dominant,lethal - all die before end of larval stage,some die during larval stage,touch sensitivity defective,touch perception defective,cell non-autonomous" "dendritic arborizing neuron,mushroom body alpha-lobe,mushroom body beta-lobe,adult antennal lobe projection neuron vPN,lateral horn,adult antennal lobe,embryonic/larval mushroom body,mushroom body pedunculus,antennal lobe,somatic clone,posterior dorsocentral bristle & mechanosensory neuron | somatic clone,anterior scutellar bristle & mechanosensory neuron | somatic clone,posterior scutellar bristle & mechanosensory neuron | somatic clone,lobe system of mushroom body,dorsal multidendritic neuron ddaC,class I dendritic arborizing neuron,posterior scutellar bristle & mechanosensory neuron,dendrite & abdominal dorsal multidendritic neuron ddaD,dendrite & abdominal dorsal multidendritic neuron ddaE,longitudinal connective,presumptive embryonic/larval central nervous system,antennal lobe glomerulus,olfactory receptor neuron,adult antennal lobe projection neuron DL1 adPN,dendritic tree | somatic clone,antennal lobe glomerulus DA1,antennal lobe glomerulus VA1v,neuroblast BLV,adult mushroom body,mushroom body,mushroom body pedunculus | third instar larval stage,antennal lobe glomerulus VA1d | pupal stage,antennal lobe glomerulus DA1 | pupal stage,antennal lobe glomerulus VA1d,ectopic,axon,commissure,Bolwig nerve,synapse,synapseppk.PG,neuron & mushroom body | somatic clone,lobe system of adult mushroom body,embryonic/larval hemocyte,mushroom body medial lobe,mushroom body vertical lobe,mechanosensory neuron,axon | ectopic,mushroom body dorsal paired medial cell,calyx of adult mushroom body,cell non-autonomous,ellipsoid body,mushroom body calyx,antennal lobe glomerulus DL1,dendrite & abdominal dorsal multidendritic neuron ddaD | somatic clone | cell autonomous,dendrite & abdominal dorsal/lateral multidendritic neuron | somatic clone | cell autonomous,dendrite & abdominal dorsal multidendritic neuron ddaA | somatic clone | cell autonomous,dendrite & abdominal dorsal multidendritic neuron ddaC | somatic clone | cell autonomous,dendrite & dendritic arborising neuron | somatic clone | cell autonomous,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,posterior commissure" FBgn0015376 cutlet cutlet http://flybase.org/reports/FBgn0015376 "FBgn0031565, FBgn0053122" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 cell proliferation ; GO:0008283 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG10030, ctl, CG33122, cutlet" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG33122 11-Aug-17 DroID_v2017_08 Drer\chtf18 "Scer\ELG1, Scer\CTF18" Cele\K08F4.1 Xtro\chtf18 Mmus\Chtf18 Hsap\CHTF18 "visible,recessive,viable,female sterile,lethal,wild-type,male sterile,partially,increased cell death,partially lethal - majority die" "ommatidium,eye photoreceptor cell,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,wing disc,somatic clone,eye disc,ventral thoracic disc,wing,egg chamber,germline cell,female,wing margin,posterior,interommatidial bristle,ocellar bristle,cone cell,eye disc & mitotic cell cycle,photoreceptor cell,supernumerary" FBgn0026411 Lim1 LIM homeobox 1 http://flybase.org/reports/FBgn0026411 "FBgn0028495, FBgn0030064" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with B-H1 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype" - "CG11354, lim1, dlim1, Dlim1, dlim-1, dLim1, BcDNA:GH04929, CG10760, Lim1, Lim" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001781:Zinc finger, LIM-type, IPR009057:Homeobox domain-like, IPR011990:Tetratricopeptide-like helical domain" CG11354 11-Aug-17 DroID_v2017_08 "Drer\lhx1b, Drer\lhx1a, Drer\hoxa10b, Drer\hoxd12a, Drer\alx3, Drer\lhx5, Drer\hoxd10a" - "Cele\dsc-1, Cele\lin-11, Cele\unc-95, Cele\mec-3" "Xtro\hoxc10, Xtro\hoxd10, Xtro\lhx5, Xtro\lhx1" "Mmus\Hoxa2, Mmus\Hoxc10, Mmus\Obox6, Mmus\Hoxa10, Mmus\Lhx1, Mmus\Nanog, Mmus\Hoxd10, Mmus\Lhx5" "Hsap\HOXA10, Hsap\HOXC10, Hsap\LHX5, Hsap\LHX1, Hsap\HOXD10" "lethal - all die before end of P-stage,recessive,some die during pharate adult stage,visible,wild-type,locomotor behavior defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,viable" "unguis,femur,tibia,antenna,arista,coxa,sternopleural bristle,vibrissae,mouthpart,third segment of antenna,larva,adult antennal lobe projection neuron DA1 vPN,eye,eye disc,somatic clone | third instar larval stage,photoreceptor cell,tarsal segment 4,tarsal segment,tarsal segment 2,tarsal segment 3,metatarsus" FBgn0027579 mino minotaur http://flybase.org/reports/FBgn0027579 - protein_coding_gene glycerol-3-phosphate O-acyltransferase activity ; GO:0004366 | inferred from sequence or structural similarity with UniProtKB:Q9HCL2 plasma membrane organization ; GO:0007009 | inferred from sequence or structural similarity with UniProtKB:Q9HCL2 phospholipid biosynthetic process ; GO:0008654 | inferred from sequence or structural similarity with UniProtKB:Q9HCL2 piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR028354 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:Q9HCL2 female germline ring canal ; GO:0035324 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG5508, 152088_at, BcDNA:GH07066, GPAT1, mino" "IPR002123:Phospholipid/glycerol acyltransferase, IPR028354:Glycerol-3-phosphate acyltransferase, PlsB, IPR022284:Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase" CG5508 11-Aug-17 DroID_v2017_08 "Drer\gpam, Drer\gpat2" - "Cele\acl-7, Cele\acl-6" Xtro\gpam "Mmus\Gpat2, Mmus\Gpam" "Hsap\GPAM, Hsap\GPAT2" "viable,male sterile,recessive,female sterile,female fertile" "salivary gland,lipid particle | ectopicppl.PP,lipid particle | ectopic48Y" FBgn0002735 E(spl)mgamma-HLH "Enhancer of split mgamma, helix-loop-helix" http://flybase.org/reports/FBgn0002735 - protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement transcription factor binding ; GO:0008134 | inferred from genetic interaction with sc inferred from genetic interaction with da sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap positive regulation of neuroblast proliferation ; GO:0002052 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement" - "CG8333, mgamma, E(spl)mgamma, e(spl)mgamma, E(spl)mB, Dm-mB, E(spl) m gamma, E(Spl) HLH-m gamma, Mgamma, E(spl)Mgamma, clone 1.49, E(spl) mgamma, E(spl)gamma, E(spl)-mgamma, HLH-mgamma, mB, anon-EST:Liang-1.49, HLHmB, HLHmgamma, bHLHb34, HlHmg, gamma, E(spl)mgamma-HLH, mg, E(spl) mg, HLHMgamma" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8333 11-Aug-17 DroID_v2017_08 "Drer\hey2, Drer\her5, Drer\LOC100149863, Drer\bhlhe40, Drer\her6, Drer\her11, Drer\hes6, Drer\her1, Drer\bhlhe41, Drer\her8.2, Drer\her4.3, Drer\her8a, Drer\her4.2, Drer\hes2.1, Drer\helt, Drer\heyl, Drer\her9, Drer\her4.4, Drer\her12, Drer\her15.2, Drer\her15.1, Drer\her3, Drer\her7, Drer\hey1, Drer\hes2.2, Drer\her13, Drer\her2" Scer\PHO4 "Cele\hlh-25, Cele\lin-22, Cele\hlh-27" "Xtro\hes2, Xtro\bhlhe41, Xtro\hey2, Xtro\hes1, Xtro\hes6.1, Xtro\hes7.2, Xtro\bhlhe40, Xtro\hes6.2, Xtro\hes7.1, Xtro\hes4, Xtro\hey1" "Mmus\Hes3, Mmus\Bhlhe41, Mmus\Hey2, Mmus\Hey1, Mmus\Hes7, Mmus\Hes5, Mmus\Helt, Mmus\Heyl, Mmus\Hes6, Mmus\Bhlhe40, Mmus\Hes1, Mmus\Hes2" "Hsap\HES2, Hsap\HELT, Hsap\BHLHE40, Hsap\HES1, Hsap\HES5, Hsap\HEY1, Hsap\HES4, Hsap\HES6, Hsap\HEY2, Hsap\BHLHE41, Hsap\HES7, Hsap\HEYL, Hsap\HES3" "increased cell number,viable,visible,neuroanatomy defective" "embryonic/larval neuroblast,macrochaeta,microchaeta,adult thorax,dorsal row & sensory mother cellap-md544,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutellar bristle,wing vein,wing margin bristle,scutum & microchaeta32B,scutum & macrochaetah-1J3,chordotonal organ precursor cell & ventral thoracic disc-109-68,type II neuroblast" FBgn0030343 ATP7 ATP7 http://flybase.org/reports/FBgn0030343 protein_coding_gene "cation-transporting ATPase activity ; GO:0019829 | inferred from electronic annotation with InterPro:IPR027256 nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR008250, InterPro:IPR023299 copper ion transmembrane transporter activity ; GO:0005375 | inferred from mutant phenotype copper ion binding ; GO:0005507 | inferred from sequence or structural similarity with UniProtKB:P35670" "metal ion transport ; GO:0030001 | inferred from electronic annotation with InterPro:IPR006121, InterPro:IPR017969 metal ion homeostasis ; GO:0055065 | inferred from mutant phenotype copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype larval development ; GO:0002164 | inferred from mutant phenotype cellular copper ion homeostasis ; GO:0006878 | inferred from mutant phenotype developmental pigmentation ; GO:0048066 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR027256 cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay" "ATP7, DmATP7, CG1886, dmATP7, lincRNA.S9122" "IPR001757:P-type ATPase, IPR006121:Heavy metal-associated domain, HMA, IPR006122:Heavy metal-associated domain, copper ion-binding, IPR008250:P-type ATPase, A domain, IPR017969:Heavy-metal-associated, conserved site, IPR018303:P-type ATPase, phosphorylation site, IPR027256:P-type ATPase, subfamily IB, IPR023298:P-type ATPase, transmembrane domain, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N" CG1886 11-Aug-17 DroID_v2017_08 "Drer\atp7a, Drer\atp7b" "Scer\PCA1, Scer\CCC2" Cele\cua-1 Xtro\atp7b "Mmus\Atp7a, Mmus\Atp7b" "Hsap\ATP7B, Hsap\ATP7A" "size defective,neuroanatomy defective,oxidative stress response defective,partially lethal - majority die,some die during pharate adult stage,locomotor behavior defective,viable,nutrition conditional,short lived,visible,lethal - all die before end of pupal stage,some die during pupal stage,male sterile,body color defective,lethal,germline clone,maternal effect,lethal - all die before end of larval stage,some die during larval stage,chemical sensitive" "pupal brain,eye,nutrition conditional,adult cuticle,macrochaeta,microchaeta,trichogen cell,mesothoracic tergum,mouth hooks,tergite,trident,macrochaeta & mesothoracic tergumpnr-MD237,scutellum,adult thorax,adult thoracic sensillum,scutellar bristle" FBgn0034113 CG8060 - http://flybase.org/reports/FBgn0034113 protein_coding_gene protein tyrosine kinase inhibitor activity ; GO:0030292 | inferred from sequence or structural similarity with HGNC:17853 negative regulation of protein tyrosine kinase activity ; GO:0061099 | inferred from sequence or structural similarity with HGNC:17853 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:17853 CG8060 "IPR000210:BTB/POZ domain, IPR000408:Regulator of chromosome condensation, RCC1, IPR002110:Ankyrin repeat, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR011333:SKP1/BTB/POZ domain, IPR020683:Ankyrin repeat-containing domain" CG8060 11-Aug-17 DroID_v2017_08 "Drer\rcbtb1, Drer\ibtk" - - Xtro\ibtk "Mmus\Rcbtb1, Mmus\Ibtk" "Hsap\IBTK, Hsap\RCBTB1" "viable,fertile" FBgn0001197 His2Av Histone H2A variant http://flybase.org/reports/FBgn0001197 FBgn0010859 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000604564 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from biological aspect of ancestor with PANTHER:PTN000604564 protein localization to chromatin ; GO:0071168 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | colocalizes_with inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay site of double-strand break ; GO:0035861 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000604564 polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay nucleosome ; GO:0000786 | inferred from direct assay "H2Av, H2A.Z, H2AV, H2AvD, His2AvD, CG5499, H2AZ, l(3)L1602, l(3)05146, l(3)97Dd, H2A.X, l(3)810, His2Av, HIS2AV, H2AX, gamma-H2Av, HisH2Av, H2av, H2A.F/Z, HIS2AVD, gamma-His2Av, H2a.V, HIS, Hist2av, H2avD, h2AvD, His2AV, his, 5499, gamma-HIS2AV, H2AV_DROM, His2, Hist, H2A, gammaH2Av, His, his2Av, His2A, H2A.V, gamma-H2AV, gammaH2AV" "IPR002119:Histone H2A, IPR007125:Histone H2A/H2B/H3, IPR009072:Histone-fold, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG5499 11-Aug-17 DroID_v2017_08 "Drer\h2afva, Drer\h2afvb, Drer\h2afz" Scer\HTZ1 Cele\htz-1 "Xtro\h2afz, Xtro\h2afv" "Mmus\H2afv, Mmus\H2afz" "Hsap\H2AFZ, Hsap\H2AFV" " adult stage | female , embryonic stage | 0-12 hr " "lethal,recessive,partially lethal - majority die,female semi-sterile,visible,wild-type,suppressor of variegation,dominant,radiation sensitive,lethal - all die before end of larval stage,some die during larval stage,enhancer of variegation,viable,some die during pupal stage,female sterile" "polytene chromosome puff | heat sensitive,eye,tarsal segment,anterior crossvein,mesothoracic tergum" DRSC16702 E -0.380515338 0.540796694 0.010369878 -2.058181484 1.179307842 0.284934271 FBgn0037166 CG11426 - http://flybase.org/reports/FBgn0037166 protein_coding_gene lipid phosphatase activity ; GO:0042577 | inferred from biological aspect of ancestor with PANTHER:PTN000807400 phosphatidate phosphatase activity ; GO:0008195 | non-traceable author statement phosphatidate phosphatase activity ; GO:0008195 | inferred from sequence or structural similarity with SGD:S000002911 phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000017950 phospholipid dephosphorylation ; GO:0046839 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 phospholipid metabolic process ; GO:0006644 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 phototransduction ; GO:0007602 | inferred from genetic interaction with rdgB inferred from genetic interaction with rdgA dephosphorylation ; GO:0016311 | non-traceable author statement phospholipid metabolic process ; GO:0006644 | inferred from sequence or structural similarity with SGD:S000002911 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 membrane ; GO:0016020 | inferred from sequence or structural similarity with SGD:S000002911 "Css1beta, WUN-like, CG11426, LPP, LPP-like, PAP2" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG11426 11-Aug-17 DroID_v2017_08 "Drer\plpp3, Drer\plppr2a, Drer\plppr3b, Drer\LOC794598, Drer\ppap2d, Drer\plpp2b, Drer\plppr2b, Drer\plppr5b, Drer\plpp2a, Drer\plppr5a, Drer\plpp1a, Drer\plppr3a, Drer\plppr1, Drer\plppr4a" "Scer\LPP1, Scer\DPP1" "Cele\F13E6.5, Cele\T28D9.3, Cele\F53C3.13, Cele\T06D8.3" "Xtro\plpp1, Xtro\LOC100135382, Xtro\plpp2, Xtro\plpp3" "Mmus\Plppr5, Mmus\Plppr2, Mmus\Plppr1, Mmus\Plppr4, Mmus\Plpp1, Mmus\Plpp2, Mmus\Plppr3, Mmus\Plpp3" "Hsap\PLPP2, Hsap\PLPPR5, Hsap\PLPP3, Hsap\PLPPR4, Hsap\PLPPR1, Hsap\PLPPR3, Hsap\PLPP1, Hsap\PLPPR2" viable "wing hair,supernumerary" DRSC11658 IK 1.902934753 0.470071708 0.005548038 0.57973259 1.519417659 1.406683511 FBgn0014029 Sep2 Septin 2 http://flybase.org/reports/FBgn0014029 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR016491, InterPro:IPR030379 GTPase activity ; GO:0003924 | inferred from direct assay NOT protein binding ; GO:0005515 | inferred from physical interaction with sip2 GTPase activity ; GO:0003924 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with pnut" cellularization ; GO:0007349 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from genetic interaction with Sep5 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from sequence or structural similarity regulation of cell cycle ; GO:0051726 | inferred from genetic interaction with Sep5 "septin complex ; GO:0031105 | inferred from direct assay septin ring ; GO:0005940 | inferred from sequence or structural similarity septin complex ; GO:0031105 | inferred from physical interaction with pnut, Sep2 microtubule associated complex ; GO:0005875 | inferred from direct assay septin complex ; GO:0031105 | inferred from physical interaction with Sep1, pnut" "sep2, CG4173, Sep2, 38961, DSep2, dSEPT2" "IPR016491:Septin, IPR030379:Septin-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4173 11-Aug-17 DroID_v2017_08 "Drer\sept7b, Drer\sept4a, Drer\sept4b, Drer\sept5b, Drer\sept2, Drer\sept5a, Drer\sept6, Drer\sept12, Drer\zgc:162239, Drer\sept8a, Drer\sept7a, Drer\sept3, Drer\zgc:63587, Drer\sept15, Drer\sept10, Drer\sept8b" "Scer\SHS1, Scer\SPR3, Scer\CDC11, Scer\CDC12, Scer\CDC10, Scer\CDC3, Scer\SPR28" "Cele\unc-61, Cele\unc-59" "Xtro\sept7, Xtro\sept2, Xtro\sept5, Xtro\sept8, Xtro\sept6, Xtro\sept10, Xtro\sept11" "Mmus\Sept10, Mmus\Sept14, Mmus\Sept4, Mmus\Sept8, Mmus\Sept3, Mmus\Sept2, Mmus\Sept1, Mmus\Sept11, Mmus\Sept12, Mmus\Sept9, Mmus\Sept7, Mmus\Sept5, Mmus\Sept6" "Hsap\SEPT9, Hsap\SEPT12, Hsap\SEPT5, Hsap\SEPT4, Hsap\SEPT10, Hsap\SEPT14, Hsap\SEPT7, Hsap\SEPT11, Hsap\SEPT2, Hsap\SEPT8, Hsap\C9orf69, Hsap\SEPT3, Hsap\SEPT6" "viable,fertile,partially lethal,maternal effect,paternal effect,male semi-sterile,female semi-sterile,cell cycle defective,some die during pharate adult stage,lethal,neuroanatomy defective,visible" "egg,maternal effect,nurse cell,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0037715 CG9399 - http://flybase.org/reports/FBgn0037715 protein_coding_gene pyruvate transmembrane transporter activity ; GO:0050833 | inferred from biological aspect of ancestor with PANTHER:PTN000365945 pyruvate transmembrane transporter activity ; GO:0050833 | inferred from sequence or structural similarity with SGD:S000001205 mitochondrial pyruvate transport ; GO:0006850 | inferred from sequence or structural similarity with SGD:S000003048 mitochondrial pyruvate transmembrane transport ; GO:1902361 | inferred from biological aspect of ancestor with PANTHER:PTN000365945 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from sequence or structural similarity with SGD:S000001205 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000365945 CG9399 IPR005336:Mitochondrial pyruvate carrier CG9399 11-Aug-17 DroID_v2017_08 "Drer\mpc2, Drer\zgc:103678" "Scer\MPC2, Scer\MPC3" Cele\F53F10.3 Xtro\mpc2 Mmus\Mpc2 Hsap\MPC2 viable DRSC16488 I 1.632597993 -0.057277898 -0.233368358 0.332414739 -0.80851097 -0.020273961 FBgn0043576 PGRP-SC1a Peptidoglycan recognition protein SC1a http://flybase.org/reports/FBgn0043576 protein_coding_gene N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | inferred from sequence or structural similarity with PGRP-SC1b peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with UniProtKB:O76537 negative regulation of innate immune response ; GO:0045824 | inferred from direct assay immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan catabolic process ; GO:0009253 | inferred from sequence or structural similarity with PGRP-SC1b extracellular region ; GO:0005576 | inferred from sequence or structural similarity "picky, PGRP-SC1A, PGRP-SC, CG14746, PGRP-SC1a, pgrp-sc, PGRP SC, PGRP-SC1, pgrp-sc1" - CG14746 11-Aug-17 DroID_v2017_08 "Drer\pglyrp6, Drer\pglyrp5, Drer\pglyrp2" - - "Xtro\pglyrp2, Xtro\pglyrp1, Xtro\pglyrp1" "Mmus\Pglyrp2, Mmus\Pglyrp4, Mmus\Pglyrp3, Mmus\Pglyrp1" "Hsap\PGLYRP1, Hsap\PGLYRP2, Hsap\PGLYRP3, Hsap\PGLYRP4" "viable,immune response defective" FBgn0041210 HDAC4 Histone deacetylase 4 http://flybase.org/reports/FBgn0041210 protein_coding_gene histone deacetylase activity ; GO:0004407 | inferred from direct assay histone deacetylase activity ; GO:0004407 | inferred from mutant phenotype "regulation of gene expression, epigenetic ; GO:0040029 | inferred from electronic annotation with InterPro:IPR030703 histone deacetylation ; GO:0016575 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay memory ; GO:0007613 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "HDAC4, DHDAC4, GC1770, dmHDA405, HDAC, CG1770, dHDAC4, HDAC4a, hdac4" "IPR000286:Histone deacetylase superfamily, IPR033660:Histone deacetylase 4, IPR030703:Histone deacetylase 5, IPR015943:WD40/YVTN repeat-like-containing domain, IPR023801:Histone deacetylase domain" CG1770 11-Aug-17 DroID_v2017_08 "Drer\hdac6, Drer\hdac7b, Drer\hdac4, Drer\hdac5, Drer\hdac10, Drer\hdac9b" "Scer\HOS3, Scer\HDA1" "Cele\hda-10, Cele\hda-5, Cele\hda-4, Cele\hda-6, Cele\F43G6.17" "Xtro\hdac9, Xtro\hdac4, Xtro\hdac7, Xtro\hdac6" "Mmus\Hdac4, Mmus\Hdac7, Mmus\Hdac10, Mmus\Hdac6, Mmus\Hdac5, Mmus\Hdac9" "Hsap\HDAC10, Hsap\HDAC5, Hsap\HDAC7, Hsap\HDAC9, Hsap\HDAC6, Hsap\HDAC4" "viable,memory defective,fertile,body color defective" mesothoracic tergum FBgn0040298 Myt1 Myt1 http://flybase.org/reports/FBgn0040298 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR016235 protein serine/threonine/tyrosine kinase activity ; GO:0004712 | inferred from direct assay protein kinase activity ; GO:0004672 | non-traceable author statement" female meiotic division ; GO:0007143 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay negative regulation of mitotic cell cycle ; GO:0045930 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogonial cell division ; GO:0007284 | inferred from mutant phenotype germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from genetic interaction with gig spermatocyte division ; GO:0048137 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR016235 Golgi apparatus ; GO:0005794 | inferred from direct assay "myt1, Dmyt1, MYT 1, dMyt1, CG10569, CG32417, Myt1, MYT1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR016235:Tyrosine/threonine-protein kinase, Cdc2 inhibitor, IPR017441:Protein kinase, ATP binding site" CG32417 11-Aug-17 DroID_v2017_08 "Drer\wee2, Drer\wee1, Drer\pkmyt1" Scer\SWE1 "Cele\Y60A9A.1, Cele\wee-1.3, Cele\wee-1.1" "Xtro\wee2, Xtro\pkmyt1" "Mmus\Wee2, Mmus\Pkmyt1, Mmus\Wee1" "Hsap\WEE2, Hsap\PKMYT1, Hsap\WEE1" "visible,mitotic cell cycle defective,male sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,viable" "ommatidium,eye disc,ommatidial precursor cluster,rhabdomere,secondary pigment cell,tertiary pigment cell,eye photoreceptor cell,supernumerary,macrochaeta & adult head64D-F),macrochaeta & adult thorax64D-F),macrochaeta & eye64D-F),cyst cell & nucleus64D-F),meiotic cell cycle64D-F),mitotic cell cycle & cystocyte64D-F),mitotic cell cycle & cystoblast64D-F),primary spermatocyte" DRSC11228 IE 1.93951296 0.05098842 0.28188664 -3.229741878 1.069769075 -0.792810332 FBgn0020379 Rfx Rfx http://flybase.org/reports/FBgn0020379 - protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000289470 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000289470 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "nervous system development ; GO:0007399 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000289470 regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement sensory perception of sound ; GO:0007605 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000289470 "dRFX, rfx, RFX, dRfx, CG6312, Rfx" "IPR003150:DNA-binding RFX-type winged-helix domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG6312 11-Aug-17 DroID_v2017_08 "Drer\rfx1a, Drer\rfx2, Drer\rfx3, Drer\rfx1b, Drer\rfx4, Drer\rfx6" Scer\RFX1 Cele\daf-19 "Xtro\rfx3, Xtro\rfx2, Xtro\rfx4, Xtro\rfx1" "Mmus\Rfx8, Mmus\Rfx2, Mmus\Rfx6, Mmus\Rfx1, Mmus\Rfx4, Mmus\Rfx3, Mmus\Rfx5" "Hsap\RFX5, Hsap\RFX3, Hsap\RFX1, Hsap\RFX8, Hsap\RFX2, Hsap\RFX6, Hsap\RFX4" "viable,fertile,smell perception defective,taste perception defective,uncoordinated,neurophysiology defective,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" "macrochaeta,antenna,Johnston's organ & scolopidium,Johnston's organ & scolopidial cilium,Johnston's organ & scolopale,sensillum campaniformium & wing sensillum & dendrite,sensillum campaniformium & wing sensillum,abdominal lateral pentascolopidial chordotonal organ lch5,abdominal lateral pentascolopidial chordotonal organ lch5 & dendrite,abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidial cilium,chordotonal organ & leg sensillumS143702),chordotonal organ & leg sensillum & scolopidial ciliumS143702)" FBgn0025808 Rad17 Rad17 http://flybase.org/reports/FBgn0025808 - protein_coding_gene chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000255944 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000255944 mitotic DNA replication checkpoint ; GO:0033314 | inferred from biological aspect of ancestor with PANTHER:PTN000255944 DNA damage checkpoint ; GO:0000077 | inferred from biological aspect of ancestor with PANTHER:PTN000255944 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000255944 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000255944 "CG7825, Rad17, DmRad17/24" "IPR004582:Checkpoint protein Rad17/Rad24, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7825 11-Aug-17 DroID_v2017_08 Drer\rad17 Scer\RAD24 Cele\hpr-17 Xtro\rad17 Mmus\Rad17 Hsap\RAD17 viable FBgn0010398 Lrr47 Leucine-rich repeat 47 http://flybase.org/reports/FBgn0010398 - protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype Ras protein signal transduction ; GO:0007265 | inferred from sequence or structural similarity with MGI:MGI:103040 lateral inhibition ; GO:0046331 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence or structural similarity extrinsic component of membrane ; GO:0019898 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Lrr-47, CT19173, LRR47, CG6098, Lrr47" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG6098 11-Aug-17 DroID_v2017_08 Drer\zgc:77287 - Cele\lrr-1 Xtro\lrr1 Mmus\Lrr1 Hsap\LRR1 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell,mesothoracic tergum" FBgn0032447 PICK1 Protein interacting with C kinase 1 http://flybase.org/reports/FBgn0032447 protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from electronic annotation with InterPro:IPR010504 phospholipid binding ; GO:0005543 | inferred from sequence model regulation of Arp2/3 complex-mediated actin nucleation ; GO:0034315 | inferred from biological aspect of ancestor with PANTHER:PTN000254123 positive regulation of developmental growth ; GO:0048639 | inferred from mutant phenotype regulated exocytosis ; GO:0045055 | inferred from expression pattern cellular response to sucrose stimulus ; GO:0071329 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000254123 neuronal cell body ; GO:0043025 | inferred from direct assay "CG6167, PICK1" "IPR001478:PDZ domain, IPR010504:Arfaptin homology (AH) domain, IPR030798:Arfaptin family, IPR027267:Arfaptin homology (AH) domain/BAR domain" CG6167 11-Aug-17 DroID_v2017_08 Drer\pick1 - "Cele\Y57G11C.22, Cele\F54C8.7" Xtro\pick1 Mmus\Pick1 Hsap\PICK1 "viable,fertile,visible" trichogen cell FBgn0053855 His1:CG33855 His1:CG33855 http://flybase.org/reports/FBgn0053855 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33855, His1:CG33855" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33855 11-Aug-17 DroID_v2017_08 "Drer\h1f0, Drer\si:dkey-23a13.17, Drer\si:dkey-108k21.21, Drer\zgc:163061, Drer\si:ch211-113a14.24, Drer\h1fx, Drer\si:ch73-368j24.12, Drer\LOC569982, Drer\si:ch73-36p18.1, Drer\h1m, Drer\si:dkey-261m9.12, Drer\si:dkey-108k21.14, Drer\histh1l, Drer\zgc:153405, Drer\si:ch1073-159d7.7, Drer\si:ch1073-153i20.4, Drer\zgc:110216, Drer\si:dkey-108k21.10, Drer\si:dkey-23a13.9, Drer\si:ch211-113a14.18, Drer\si:ch73-368j24.11, Drer\zgc:110425" Scer\HHO1 "Cele\hil-3, Cele\hil-6, Cele\hil-2, Cele\hil-5, Cele\his-24, Cele\hil-4" - "Mmus\H1fx, Mmus\Hist1h1d, Mmus\H1foo, Mmus\Hils1, Mmus\Hist1h1t, Mmus\Hist1h1c, Mmus\H1fnt, Mmus\Hist1h1e, Mmus\Hist1h1b, Mmus\Hist1h1a" "Hsap\HIST1H1T, Hsap\H1FX, Hsap\HIST1H1B, Hsap\HIST1H1D, Hsap\H1FOO, Hsap\H1F0, Hsap\HIST1H1E, Hsap\HIST1H1C, Hsap\H1FNT, Hsap\HIST1H1A" FBgn0003507 srp serpent http://flybase.org/reports/FBgn0003507 "FBgn0010376, FBgn0010753, FBgn0011478" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088 DNA binding ; GO:0003677 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:4170 inferred from sequence or structural similarity with HGNC:4171 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay RNA polymerase II transcription factor binding ; GO:0001085 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with ush sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype fat body development ; GO:0007503 | traceable author statement germ-band shortening ; GO:0007390 | traceable author statement germ cell migration ; GO:0008354 | inferred from mutant phenotype midgut development ; GO:0007494 | traceable author statement hemocyte development ; GO:0007516 | traceable author statement embryonic hemopoiesis ; GO:0035162 | traceable author statement hemopoiesis ; GO:0030097 | traceable author statement cell fate commitment ; GO:0045165 | traceable author statement larval lymph gland hemopoiesis ; GO:0035167 | traceable author statement cell fate determination ; GO:0001709 | traceable author statement head involution ; GO:0008258 | non-traceable author statement germ cell migration ; GO:0008354 | traceable author statement lymph gland development ; GO:0048542 | inferred from mutant phenotype hemocyte development ; GO:0007516 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype crystal cell differentiation ; GO:0042688 | traceable author statement negative regulation of crystal cell differentiation ; GO:0042690 | traceable author statement hemopoiesis ; GO:0030097 | inferred from expression pattern inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype amnioserosa maintenance ; GO:0046665 | traceable author statement mesodermal cell fate commitment ; GO:0001710 | inferred from mutant phenotype embryonic hemopoiesis ; GO:0035162 | inferred from mutant phenotype fat body development ; GO:0007503 | inferred from expression pattern dorsal closure ; GO:0007391 | traceable author statement endoderm development ; GO:0007492 | traceable author statement autophagy ; GO:0006914 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype amnioserosa maintenance ; GO:0046665 | inferred from mutant phenotype endoderm formation ; GO:0001706 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 "CG3992, Srp, GATA, dGATAb, ABF, GATAb, DmGATAb, l(3)01549, A7.1, spt, l(3)neo45, l(3)89B2, abf, Abf, srp, SRP, srpD" "IPR013088:Zinc finger, NHR/GATA-type, IPR000679:Zinc finger, GATA-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG3992 11-Aug-17 DroID_v2017_08 "Drer\gata1a, Drer\gata6, Drer\gata2b, Drer\gata1b, Drer\gata4, Drer\gata3, Drer\zglp1, Drer\trps1, Drer\gata2a, Drer\gata5" "Scer\GLN3, Scer\ECM23, Scer\GAT4, Scer\GAT2, Scer\DAL80, Scer\SRD1, Scer\GAT3, Scer\GZF3, Scer\GAT1" "Cele\elt-6, Cele\elt-7, Cele\elt-4, Cele\elt-1, Cele\elt-3, Cele\elt-2, Cele\end-1, Cele\med-2, Cele\med-1, Cele\egl-18, Cele\end-3" "Xtro\gata2, Xtro\gata1, Xtro\gata3, Xtro\gata5, Xtro\gata4, Xtro\gata6, Xtro\trps1" "Mmus\Trps1, Mmus\Zglp1, Mmus\Gata6, Mmus\Gata5, Mmus\Gata1, Mmus\Gata2, Mmus\Gata4, Mmus\Gata3" "Hsap\GATA3, Hsap\ZGLP1, Hsap\GATA1, Hsap\GATA2, Hsap\GATA5, Hsap\TRPS1, Hsap\GATA4, Hsap\GATA6" " embryonic stage | stage 5 , embryonic stage | stage 11 , embryonic stage&&larval stage&&adult stage , embryonic stage | stage 5-9 , embryonic stage | stage 5-12 , embryonic stage | stage 6 , embryonic stage | >stage 12 " " vitellophage

, prohemocyte

, anterior midgut proper primordium

, posterior midgut proper primordium

, head mesoderm

, amnioserosa

, fat body

, prohemocyte | primordium

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective,small body,cell migration defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/first instar larval cuticle,crystal cell,embryonic/larval lymph gland,embryonic/larval hemocyte,embryonic/larval tracheocyte,precursor,ventral midline,extended germ band embryo,macrochaeta,dorsal,amnioserosa,presumptive embryonic/larval central nervous system,embryonic/larval glial cell,embryonic hemocyte,plasmatocyte,abdomen,posterior,midgut primordium,embryonic/larval fat body,embryonic/larval midgut,germline cell,embryonic Malpighian tubule,presumptive embryonic salivary gland,visceral mesoderm,lymph gland primordium,dorsal closure embryo,midgut,embryo,embryonic head,cephalopharyngeal skeleton,dorsal bridge,vertical bridge,cuticle,ectopic,crystal cell | embryonic stage,plasmatocyte | embryonic stage,cardioblast,embryonic/larval garland cell,fat body/gonad primordium,gonadal sheath,embryonic/larval somatic muscle,midgut constriction,cardiogenic mesoderm,embryonic pericardial cell,posterior signalling centre of lymph gland primary lobe" DRSC23166 K 1.931612853 0.846987766 FBgn0000629 E(z) Enhancer of zeste http://flybase.org/reports/FBgn0000629 FBgn0004710 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay histone methyltransferase activity ; GO:0042054 | inferred from direct assay histone methyltransferase activity (H3-K27 specific) ; GO:0046976 | inferred from mutant phenotype DNA binding ; GO:0003677 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 histone methyltransferase activity (H3-K27 specific) ; GO:0046976 | inferred from direct assay histone methyltransferase activity ; GO:0042054 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24459 histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | inferred from direct assay histone methyltransferase activity ; GO:0042054 | contributes_to inferred from direct assay histone methyltransferase activity (H3-K27 specific) ; GO:0046976 | traceable author statement" "histone H3-K27 methylation ; GO:0070734 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay histone H3-K27 methylation ; GO:0070734 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype histone H3-K9 methylation ; GO:0051567 | inferred from direct assay axon guidance ; GO:0007411 | inferred from mutant phenotype gene silencing ; GO:0016458 | non-traceable author statement histone methylation ; GO:0016571 | traceable author statement cuticle hydrocarbon biosynthetic process ; GO:0006723 | inferred from mutant phenotype syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype histone methylation ; GO:0016571 | inferred from mutant phenotype histone methylation ; GO:0016571 | inferred from direct assay inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement" nucleus ; GO:0005634 | inferred from direct assay nuclear chromatin ; GO:0000790 | non-traceable author statement ESC/E(Z) complex ; GO:0035098 | inferred from direct assay histone methyltransferase complex ; GO:0035097 | inferred from direct assay "E(z), EZ, E(Z), CG6502, E(z)1, Ez, E[z], Su(z)301, pco, l(3)67Fa, l(3)1902, pco/E(z), l(3)ds12, l(3)SG17, l(3)B12, EZH1/2" "IPR001005:SANT/Myb domain, IPR001214:SET domain, IPR026489:CXC domain, IPR033467:Tesmin/TSO1-like CXC domain" CG6502 11-Aug-17 DroID_v2017_08 "Drer\ezh1, Drer\setd7, Drer\ezh2" Scer\SET2 Cele\mes-2 "Xtro\ezh2, Xtro\ezh1, Xtro\setd7" "Mmus\Ezh2, Mmus\Ezh1, Mmus\Setd7" "Hsap\EZH1, Hsap\SETD7, Hsap\EZH2" " embryonic stage -- adult stage , adult stage | male , larval stage && pupal stage " " larval stage | third instar , embryonic stage "

ubiquitous "female sterile,endomitotic cell cycle defective,viable,lethal,recessive,visible,dominant,homeotic,eye color defective,wild-type,neuroanatomy defective,somatic clone,decreased cell number,mitotic cell cycle defective,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,fertile,poor,lethal - all die before end of larval stage,some die during larval stage,maternal effect,non-suppressor of variegation,non-enhancer of variegation,suppressor of variegation,partially lethal - majority die,some die during pupal stage" "egg chamber,oocyte nucleus,karyosome,germarium region 2b,adult metathoracic segment,adult mesothoracic segment,ectopic,adult abdominal segment 5,adult abdominal segment 4,adult prothoracic segment,mesothoracic leg & sex comb | ectopic,sex comb,pigment cell,mesothoracic leg,axon | somatic clone,CNS glial cell,somatic clone,neuroblast,wing,segment,heat sensitive,polytene chromosome | heat sensitive,wing disc,haltere disc,adult abdominal segment 6,adult abdominal segment 7,haltere,humerus,female genitalia,ventral,male genitalia,leg,posterior compartment,triple row,tergite,metathoracic leg,egg,nurse cell,imaginal disc,maternal effect,larval abdominal segment 1,larval abdominal segment 2,larval abdominal segment 3,larval abdominal segment 4,larval abdominal segment 5,larval abdominal segment 6,larval abdominal segment 7,larval abdominal segment 8,larval abdominal segment 9,larval abdominal segment 10,larval abdominal segment 11,larval thorax,photoreceptor cell,eye,eye disc,morphogenetic furrow,metaphase & condensed chromosome & embryo,dendrite & dorsal multidendritic neuron ddaC | somatic clone,larval brain & mitosis & nuclear chromosome,cell cycle,eye-antennal disc,ventral thoracic disc,genital disc,mesothoracic tergum" FBgn0004969 ado adolescent http://flybase.org/reports/FBgn0004969 - gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - "l(1)4P1, ado" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "chorion | germline clone,dorsal appendage,germline clone,ovary,ovariole,somatic clone,egg" FBgn0262389 mir-1017 mir-1017 stem loop http://flybase.org/reports/FBgn0262389 miRNA_gene - - - "miR-1017, dme-mir-1017, mir-1017, CR42919" - CR42919 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0035627 Sse Separase http://flybase.org/reports/FBgn0035627 protein_coding_gene "peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR005314, InterPro:IPR030397 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P42286" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR005314, InterPro:IPR030397 mitotic sister chromatid segregation ; GO:0000070 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype" "polytene chromosome ; GO:0005700 | inferred from direct assay nuclear chromosome, telomeric region ; GO:0000784 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay" "sse, SSE, l(3)SG14, l(3)13m-281, CG10583, Sse" "IPR030397:SEPARIN core domain, IPR005314:Peptidase C50, separase" CG10583 11-Aug-17 DroID_v2017_08 Drer\espl1 Scer\ESP1 "Cele\sep-1, Cele\ZK430.5" Xtro\espl1 Mmus\Espl1 Hsap\ESPL1 "mitotic cell cycle defective,viable,fertile,lethal,recessive,somatic clone,lethal - all die before end of larval stage,some die during larval stage,wild-type,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "mitotic cell cycle,embryonic/larval brain,somatic clone,embryonic/larval neuroblast,mitotic cell cycleSseA),imaginal disc,cell cycle,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC09746 E -0.772159165 0.474464403 1.269786476 -1.625495694 -0.067193321 -1.04068294 FBgn0029512 Aos1 Activator of SUMO 1 http://flybase.org/reports/FBgn0029512 protein_coding_gene "small protein activating enzyme activity ; GO:0008641 | inferred from electronic annotation with InterPro:IPR000011, InterPro:IPR000594 SUMO activating enzyme activity ; GO:0019948 | inferred from sequence or structural similarity ubiquitin activating enzyme binding ; GO:0033134 | inferred from physical interaction with Uba2 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with lwr" positive regulation of MyD88-dependent toll-like receptor signaling pathway ; GO:0034126 | inferred from mutant phenotype protein sumoylation ; GO:0016925 | inferred from sequence or structural similarity positive regulation of NF-kappaB transcription factor activity ; GO:0051092 | inferred from direct assay regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype protein sumoylation ; GO:0016925 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay SUMO activating enzyme complex ; GO:0031510 | inferred from sequence or structural similarity "SAE1, CG12276, DmAos1, Sae1, DmSae1, Dmaos1, DmSAE1, Aos1, Aos, AOS1" "IPR000011:Ubiquitin/SUMO-activating enzyme E1, IPR000594:THIF-type NAD/FAD binding fold" CG12276 11-Aug-17 DroID_v2017_08 "Drer\nae1, Drer\sae1" "Scer\AOS1, Scer\ULA1" "Cele\aos-1, Cele\ula-1" "Xtro\sae1, Xtro\nae1" "Mmus\Sae1, Mmus\Nae1" "Hsap\SAE1, Hsap\NAE1" "developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,melanotic mass phenotype,increased cell death,somatic clone,cell lethal,decreased cell number,somatic clone - Minute background,mitotic cell cycle defective,lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal,neuroanatomy defective,partially lethal - majority die,visible" "imaginal disc,embryonic/larval optic lobe,somatic clone,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,eye,eye disc,adult head" FBgn0035088 CG3776 - http://flybase.org/reports/FBgn0035088 protein_coding_gene ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 protein binding ; GO:0005515 | inferred from physical interaction with Jhe inner mitochondrial membrane organization ; GO:0007007 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex III biogenesis ; GO:0097033 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex IV biogenesis ; GO:0097034 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 protein insertion into mitochondrial membrane from inner side ; GO:0032979 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrion ; GO:0005739 | inferred from direct assay "EP(2)0835, CG3776, P29, DmP29, Jhebp29" - CG3776 11-Aug-17 DroID_v2017_08 "Drer\zgc:123096, Drer\si:dkey-82o10.4" Scer\MBA1 "Cele\F40G9.6, Cele\Y62E10A.20" Xtro\c2orf47 Mmus\Maip1 Hsap\MAIP1 "visible,partially lethal - majority die,some die during pupal stage,female fertile,short lived,male,female,male fertile,female sterile,heat sensitive,lethal,small body,courtship behavior defective,locomotor behavior defective" "trichogen cell,mesothoracic tergum" FBgn0259468 C345 - http://flybase.org/reports/FBgn0259468 gene - - - C345 - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,lethal" "wing hair,chaeta" FBgn0000887 fs(1)M85 female sterile (1) M85 http://flybase.org/reports/FBgn0000887 - gene - - - fs(1)M85 - - 11-Aug-17 DroID_v2017_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0020847 l(1)3Db lethal (1) 3Db http://flybase.org/reports/FBgn0020847 - gene - - - "X1, l(1)3Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "external sensory organ,multidendritic neuron,axon" FBgn0002946 nob no bridge http://flybase.org/reports/FBgn0002946 - gene - adult walking behavior ; GO:0007628 | traceable author statement response to pain ; GO:0048265 | inferred from mutant phenotype - nob - - 11-Aug-17 DroID_v2017_08 - - - - - - "short lived,female sterile,recessive,lethal,female,partially,viable,male,uncoordinated,memory defective,behavior defective,locomotor behavior defective" "protocerebral bridge,protocerebral bridge slice,fan-shaped body" FBgn0034997 CG3376 - http://flybase.org/reports/FBgn0034997 protein_coding_gene sphingomyelin phosphodiesterase activity ; GO:0004767 | inferred from electronic annotation with InterPro:IPR011160 sphingomyelin catabolic process ; GO:0006685 | inferred from electronic annotation with InterPro:IPR011160 - "aSMase, CG3376" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR008139:Saposin B type domain, IPR011001:Saposin-like, IPR011160:Sphingomyelin phosphodiesterase, IPR029052:Metallo-dependent phosphatase-like" CG3376 11-Aug-17 DroID_v2017_08 "Drer\smpd1, Drer\smpdl3b, Drer\smpdl3a" Scer\PPN1 "Cele\asm-2, Cele\asm-3, Cele\ZK856.5, Cele\asm-1" "Xtro\smpdl3a, Xtro\smpd1" "Mmus\Smpd1, Mmus\Smpdl3a, Mmus\Smpdl3b" "Hsap\SMPDL3B, Hsap\SMPDL3A, Hsap\SMPD1" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0000520 dwg deformed wings http://flybase.org/reports/FBgn0000520 "FBgn0003974, FBgn0024976, FBgn0026052" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 protein binding ; GO:0005515 | inferred from physical interaction with BEAF-32 chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay - nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "zw5, SBP, Zw5, Zw-5, EG:95B7.6, CG2711, zw-5, ves, l(1)zw5, ZW-5, l(1)3Be, Sbp, dwg, CG2714, ZW5, DWG" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2711 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-7l6.3, Drer\LOC568955, Drer\LOC798048, Drer\si:ch211-89o9.6, Drer\vezf1b, Drer\si:ch211-207i20.2, Drer\si:ch211-166g5.4, Drer\si:dkey-56e3.3, Drer\si:dkeyp-2e4.6, Drer\znf1068, Drer\gtf3aa, Drer\si:ch211-155e24.3, Drer\si:dkey-210j14.3, Drer\znf569l" Scer\PZF1 "Cele\Y55F3AM.14, Cele\ztf-14, Cele\hinf-1, Cele\let-391, Cele\pag-3, Cele\zag-1, Cele\F58G1.2, Cele\klu-1, Cele\F10B5.3, Cele\F21A9.2, Cele\row-1, Cele\pqm-1" "Xtro\vezf1, Xtro\znf160, Xtro\maz, Xtro\patz1" "Mmus\Zscan2, Mmus\Mzf1, Mmus\Gtf3a, Mmus\Zfp426, Mmus\Zfp583, Mmus\Vezf1, Mmus\9130023H24Rik, Mmus\Maz" "Hsap\ZNF497, Hsap\MAZ, Hsap\ZNF394, Hsap\MZF1, Hsap\ZSCAN2, Hsap\ZSCAN22, Hsap\VEZF1, Hsap\ZNF846, Hsap\ZNF583, Hsap\ZNF594, Hsap\GTF3A" "lethal,recessive,wild-type,viable,reduced,male sterile,visible,male,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,polyphasic,cell lethal,germline clone" "wing,eye,wing vein,macrochaeta,pigment cell,anterior orbital bristle,middle orbital bristle,posterior orbital bristle,ocellar bristle,anterior vertical bristle,posterior vertical bristle,vibrissae" FBgn0039492 CG6051 - http://flybase.org/reports/FBgn0039492 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 - - "CG6051, blr2" "IPR000306:FYVE zinc finger, IPR011011:Zinc finger, FYVE/PHD-type, IPR017455:Zinc finger, FYVE-related, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6051 11-Aug-17 DroID_v2017_08 "Drer\rundc3aa, Drer\pikfyve, Drer\zfyve28, Drer\rundc3b, Drer\rundc3ab" "Scer\PIB2, Scer\FAB1" "Cele\ppk-3, Cele\lst-2" Xtro\zfyve28 "Mmus\Zfyve19, Mmus\Rundc3b, Mmus\Zfyve28, Mmus\Rufy2, Mmus\Pikfyve, Mmus\Rundc3a" "Hsap\RUNDC3A, Hsap\ZFYVE28, Hsap\RUFY2, Hsap\PIKFYVE, Hsap\RUNDC3B, Hsap\ZFYVE19" "lethal - all die before end of larval stage,viable,visible" "embryonic/larval muscle system,mesothoracic tergum" DRSC15956 E -0.165553119 0.91878573 0.315818125 -3.043237715 -1.463975992 -0.699439704 FBgn0004646 ogre optic ganglion reduced http://flybase.org/reports/FBgn0004646 "FBgn0000265, FBgn0002988, FBgn0029926" protein_coding_gene gap junction channel activity ; GO:0005243 | inferred by curator from GO:0005921 intercellular transport ; GO:0010496 | inferred from sequence or structural similarity with Inx3 phototransduction ; GO:0007602 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from sequence or structural similarity basolateral plasma membrane ; GO:0016323 | inferred from direct assay gap junction ; GO:0005921 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q9XYN0 "inx-1, l(1)ogre, Dm-inx1, inx1, Inx1, jnL3, l(1)jnL3, l(1)6Ec, cb-8, CG3039, CB8, ogre, FBpp0070995, Ogre" IPR000990:Innexin CG3039 11-Aug-17 DroID_v2017_08 "Drer\panx3, Drer\panx1b" - "Cele\inx-7, Cele\inx-11, Cele\inx-8, Cele\inx-1, Cele\inx-22, Cele\inx-2, Cele\inx-10, Cele\eat-5, Cele\inx-20, Cele\inx-17, Cele\inx-3, Cele\inx-9, Cele\inx-5, Cele\inx-13, Cele\inx-21, Cele\inx-6, Cele\unc-7, Cele\che-7, Cele\inx-14, Cele\inx-18, Cele\inx-15, Cele\inx-12, Cele\inx-16, Cele\inx-19, Cele\unc-9" - - - "viable,fertile,wild-type,lethal,recessive,heat sensitive,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,cell lethal,germline clone" "optic lobe,central nervous system,lamina monopolar neuron,photoreceptor cell" FBgn0259958 Sfp24F Seminal fluid protein 24F http://flybase.org/reports/FBgn0259958 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with lectin-37Da multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp24F, CG42468, SFP24F" "IPR016187:C-type lectin fold, IPR016186:C-type lectin-like/link domain, IPR001304:C-type lectin-like" CG42468 11-Aug-17 DroID_v2017_08 Drer\si:ch73-343l4.8 - - - "Mmus\Cd209e, Mmus\Cd209c, Mmus\Clec4e, Mmus\Clec12b, Mmus\Gm156, Mmus\Clec4g, Mmus\Clec9a, Mmus\Cd209b, Mmus\Cd209a" "Hsap\CLEC4D, Hsap\CLEC6A, Hsap\CLEC4E" FBgn0034214 CG6550 - http://flybase.org/reports/FBgn0034214 protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR005839, InterPro:IPR013848, InterPro:IPR020612 N6-threonylcarbomyladenosine methylthiotransferase activity ; GO:0035598 | inferred from biological aspect of ancestor with PANTHER:PTN000228709" RNA modification ; GO:0009451 | inferred from electronic annotation with InterPro:IPR013848 endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000228711 CG6550 "IPR002792:TRAM domain, IPR005839:Methylthiotransferase, IPR006466:MiaB-like tRNA modifying enzyme, archaeal-type, IPR006638:Elongator protein 3/MiaB/NifB, IPR007197:Radical SAM, IPR013848:Methylthiotransferase, N-terminal, IPR023404:Radical SAM, alpha/beta horseshoe, IPR020612:Methylthiotransferase, conserved site" CG6550 11-Aug-17 DroID_v2017_08 "Drer\cdk5rap1, Drer\cdkal1" - "Cele\Y92H12BL.1, Cele\F25B5.5" Xtro\cdkal1 "Mmus\Cdkal1, Mmus\Cdk5rap1" "Hsap\CDK5RAP1, Hsap\CDKAL1" viable DRSC07001 I 1.867450901 -0.315624744 1.406763782 0.217958622 -1.32892967 -0.424364494 FBgn0039589 CG9986 - http://flybase.org/reports/FBgn0039589 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9986 IPR019311:Protein of unknown function DUF2362 CG9986 11-Aug-17 DroID_v2017_08 Drer\zgc:154077 - "Cele\C55A6.10, Cele\dhs-14" Xtro\c12orf4 "Mmus\D6Wsu163e, Mmus\Jun" "Hsap\C12orf4, Hsap\JUN, Hsap\MEIS1, Hsap\UACA" "viable,fertile" FBgn0010263 Rbp9 RNA-binding protein 9 http://flybase.org/reports/FBgn0010263 "FBgn0010253, FBgn0031482" protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002343, InterPro:IPR006548 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | non-traceable author statement" establishment of blood-brain barrier ; GO:0060856 | inferred from mutant phenotype germ cell proliferation ; GO:0036093 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | traceable author statement nucleus ; GO:0005634 | traceable author statement "fs(2)B, fes, rbp9, RBP9, RRM9, RRM10, RBP9-2, rbp9a, rbp, rrm9, rrm10, Rbp10, CG15402, CG3151, Rbp9, Rpb9" "IPR000504:RNA recognition motif domain, IPR002343:Paraneoplastic encephalomyelitis antigen, IPR006548:Splicing factor ELAV/HuD" CG3151 11-Aug-17 DroID_v2017_08 "Drer\elavl4, Drer\rbms1a, Drer\rbms3, Drer\fam213b, Drer\elavl2, Drer\elavl3, Drer\rbms2a, Drer\rbms2b, Drer\nol8, Drer\hug, Drer\elavl1" "Scer\PAB1, Scer\GBP2" Cele\exc-7 "Xtro\elavl3, Xtro\elavl4, Xtro\elavl2, Xtro\elavl1" "Mmus\Rbms2, Mmus\Elavl3, Mmus\Elavl1, Mmus\Fam213b, Mmus\Rbms1, Mmus\Elavl4, Mmus\Rbms3, Mmus\Elavl2" "Hsap\ELAVL4, Hsap\RBMS1, Hsap\FAM213B, Hsap\ELAVL1, Hsap\RBMS3, Hsap\RBMS2, Hsap\ELAVL2, Hsap\ELAVL3" " larval stage | third instar , pupal stage && adult stage "

" pupal stage && adult stage , adult stage , pupal stage | late " " thoracico-abdominal ganglion

, antenna

, cell body &&of lamina

, cell body &&of adult brain

" "viable,female sterile,locomotor behavior defective,conditional,short lived,partially,wild-type,recessive,lethal,partially lethal - majority die,visible,body color defective" "ovariole,cystocyte,egg chamber,germarium,nurse cell,fusome,mesothoracic tergum" FBgn0032078 C1GalTA Core 1 Galactosyltransferase A http://flybase.org/reports/FBgn0032078 protein_coding_gene "beta-1,3-galactosyltransferase activity ; GO:0048531 | inferred from direct assay glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from direct assay glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from mutant phenotype" "negative regulation of hematopoietic stem cell differentiation ; GO:1902037 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype protein glycosylation ; GO:0006486 | inferred from direct assay O-glycan processing, core 1 ; GO:0016267 | inferred from mutant phenotype central nervous system morphogenesis ; GO:0021551 | inferred from mutant phenotype regulation of filopodium assembly ; GO:0051489 | inferred from mutant phenotype glycolipid biosynthetic process ; GO:0009247 | inferred from direct assay muscle cell development ; GO:0055001 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9NS00 "anon-WO0144478.18, dC1GalT, CG9520, dC1beta3GalT1, C1GalTA, C1GALT1, dC1GalT1, C1beta3GalT1" "IPR003378:Fringe-like, IPR026842:C1GALT1" CG9520 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-202e17.1, Drer\c1galt1b, Drer\LOC564281, Drer\c1galt1a, Drer\c1galt1c1" - "Cele\F37A4.3, Cele\E03H4.3, Cele\bus-4, Cele\C38H2.2, Cele\C17A2.3, Cele\F56H6.1, Cele\T09E11.12, Cele\Y38C1AB.5, Cele\C16D9.6, Cele\C02H6.1, Cele\W09D10.5, Cele\Y38C1AB.1" "Xtro\c1galt1, Xtro\LOC100496837" "Mmus\C1galt1, Mmus\C1galt1c1" "Hsap\C1GALT1C1, Hsap\C1GALT1" "viable,fertile,lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,partially" "ventral nerve cord,embryonic/larval brain,leg,plasmatocyte" FBgn0035498 Fit1 Fermitin 1 http://flybase.org/reports/FBgn0035498 protein_coding_gene cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity with UniProtKB:Q18685 cell-matrix adhesion ; GO:0007160 | inferred from sequence or structural similarity with UniProtKB:Q18685 cardiac muscle tissue development ; GO:0048738 | inferred from genetic interaction with Fit2 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q18685 "fit1, CG14991, anon-WO0118547.421, Fit1, fit 1, Fit 1" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle" CG14991 11-Aug-17 DroID_v2017_08 "Drer\fermt1, Drer\fermt2, Drer\im:7154036, Drer\fermt3b" - Cele\unc-112 "Xtro\fermt2, Xtro\fermt3, Xtro\fermt1" "Mmus\Fermt1, Mmus\Fermt2, Mmus\Fermt3" "Hsap\FERMT3, Hsap\FERMT2, Hsap\FERMT1" "some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0053002 mRpL27 mitochondrial ribosomal protein L27 http://flybase.org/reports/FBgn0053002 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000000486 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001684 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with SGD:S000000486 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000000486 "CG15442, CG33002, mRpL27" IPR001684:Ribosomal protein L27 CG33002 11-Aug-17 DroID_v2017_08 Drer\mrpl27 Scer\MRP7 Cele\Y54G11A.17 Xtro\mrpl27 Mmus\Mrpl27 Hsap\MRPL27 "viable,visible" trichogen cell FBgn0026179 siz schizo http://flybase.org/reports/FBgn0026179 "FBgn0037047, FBgn0037048, FBgn0037049, FBgn0052434" protein_coding_gene ARF guanyl-nucleotide exchange factor activity ; GO:0005086 | inferred from electronic annotation with InterPro:IPR000904 cadherin binding ; GO:0045296 | inferred from direct assay regulation of ARF protein signal transduction ; GO:0032012 | inferred from electronic annotation with InterPro:IPR000904 myoblast fusion ; GO:0007520 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of ARF protein signal transduction ; GO:0032012 | inferred by curator from GO:0005086 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - "CG32434, loner, CG10577, CG12981, CG12980, siz, Loner, schizo" "IPR000048:IQ motif, EF-hand binding site, IPR000904:Sec7 domain, IPR011993:PH domain-like, IPR023394:Sec7 domain, alpha orthogonal bundle, IPR033742:IQ motif and SEC7 domain-containing protein, PH domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG32434 11-Aug-17 DroID_v2017_08 "Drer\iqsec3a, Drer\iqsec1b, Drer\iqsec2, Drer\iqsec1a, Drer\LOC560461, Drer\iqsec3b" "Scer\SYT1, Scer\SEC7, Scer\BOI2" Cele\bris-1 "Xtro\iqsec1, Xtro\iqsec2, Xtro\iqsec3" "Mmus\Iqsec1, Mmus\Iqsec3, Mmus\Iqsec2" "Hsap\IQSEC2, Hsap\IQSEC1, Hsap\IQSEC3" "behavior defective,recessive,viable,fertile,lethal" "ventral nerve cord commissure,commissure,midline glial cell,longitudinal connective,embryonic myoblast,fusion competent cell" FBgn0033113 Spn42Dc Serpin 42Dc http://flybase.org/reports/FBgn0033113 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "Spn42Dc, CG9455" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG9455 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-186e20.7, Drer\serpinc1, Drer\serpinf1, Drer\serpind1, Drer\serpina7, Drer\serpinb1, Drer\serpinf2b, Drer\zgc:174259, Drer\serpinh1a, Drer\serpina1l, Drer\serpine2, Drer\agt, Drer\serpinh1b, Drer\serpinb1l3, Drer\serping1, Drer\zgc:173729, Drer\serpinf2a, Drer\serpinb1l2, Drer\serpine1, Drer\serpini1, Drer\si:ch1073-416d2.3, Drer\serpine3" - "Cele\srp-3, Cele\srp-7, Cele\srp-2, Cele\srp-1, Cele\srp-6, Cele\C28G1.2, Cele\srp-8" "Xtro\serpinh1, Xtro\serpina1, Xtro\serpinb4, Xtro\serpina3m, Xtro\serpini2, Xtro\serpinb1, Xtro\serpinb11, Xtro\serpine2, Xtro\serpinb5, Xtro\serpinc1, Xtro\serpina3, Xtro\serpina3k, Xtro\serpini1, Xtro\serpind1, Xtro\serpinb6, Xtro\serpina10, Xtro\serpine1" "Mmus\Serpinb9f, Mmus\Serpinb12, Mmus\Serpinb6a, Mmus\Serpini1, Mmus\Serpinb13, Mmus\Serpina3i, Mmus\Serpina3g, Mmus\Serpinb5, Mmus\Serpinb3c, Mmus\Serpinb9b, Mmus\Serpinf1, Mmus\Serpinb6e, Mmus\Serpina1c, Mmus\Serpina12, Mmus\Serpina16, Mmus\Serpinb9d, Mmus\Serpinb6d, Mmus\Serpina3f, Mmus\Serpina3a, Mmus\Serpine3, Mmus\Serpini2, Mmus\Serpinb1a, Mmus\Serpinb3a, Mmus\Serpina6, Mmus\Serpina3n, Mmus\Agt, Mmus\Serpine2, Mmus\Serpine1, Mmus\Serpinb2, Mmus\Serpina9, Mmus\Serpina1d, Mmus\Serpinb9e, Mmus\Serpinb9, Mmus\Serpina1a, Mmus\Serpinb1c, Mmus\Gm11397, Mmus\Serpinb3d, Mmus\Serpina3c, Mmus\Serpinc1, Mmus\Serpinb9g, Mmus\Serpina3k, Mmus\Serpinb9c, Mmus\Serpinh1, Mmus\Serpina1f, Mmus\Serpinb8, Mmus\Serpina1e, Mmus\Serpinb6c, Mmus\Serpina11, Mmus\Serpinb11, Mmus\Serpina3j, Mmus\Serpinf2, Mmus\Serpina7, Mmus\Serpina10, Mmus\Serpinb6b, Mmus\Serpina5, Mmus\Serpinb1b, Mmus\Serpind1, Mmus\Serpinb7" "Hsap\SERPINB10, Hsap\SERPINB1, Hsap\SERPINA12, Hsap\SERPINE1, Hsap\SERPINB9, Hsap\SERPINA5, Hsap\SERPINC1, Hsap\SERPINF2, Hsap\HMSD, Hsap\SERPINH1, Hsap\SERPINA7, Hsap\SERPINE3, Hsap\SERPINB2, Hsap\SERPINF1, Hsap\SERPINB5, Hsap\SERPINA9, Hsap\SERPINB6, Hsap\SERPINA11, Hsap\SERPINA3, Hsap\AGT, Hsap\SERPINI1, Hsap\SERPINA10, Hsap\SERPINB13, Hsap\SERPINB7, Hsap\SERPINE2, Hsap\SERPINB8, Hsap\SERPINB4, Hsap\SERPINB11, Hsap\SERPINI2, Hsap\SERPINA6, Hsap\SERPINA4, Hsap\SERPIND1, Hsap\SERPINA1, Hsap\SERPINB12" "visible,viable" "wing vein,ectopic" DRSC05010 IE 4.669816785 1.259618237 1.704465548 0.475985309 -0.428844766 0.01895451 FBgn0267912 CanA-14F Calcineurin A at 14F http://flybase.org/reports/FBgn0267912 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9XZL8 calmodulin-dependent protein phosphatase activity ; GO:0033192 | inferred from mutant phenotype protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from direct assay protein dephosphorylation ; GO:0006470 | non-traceable author statement - "CanA-14F, CG9819, DmCanA-14F, canA-14F, PP2B, CnnA14D, D27, CnnA14D(I), PpD27, MRE12" "IPR029052:Metallo-dependent phosphatase-like, IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase" CG9819 11-Aug-17 DroID_v2017_08 "Drer\ppp3cca, Drer\ppp3cb, Drer\ppp3ccb, Drer\ppp3ca" "Scer\CMP2, Scer\CNA1" Cele\tax-6 "Xtro\ppp3cb, Xtro\ppp3ca, Xtro\ppp3cc" "Mmus\Ppp3cb, Mmus\Ppp3cc, Mmus\Ppp3ca" "Hsap\PPP3CA, Hsap\PPP3CB, Hsap\PPP3CC" "viable,fertile,sleep defective,locomotor behavior defective,lethal,heat sensitive,hyperactive" FBgn0037465 CG1105 - http://flybase.org/reports/FBgn0037465 protein_coding_gene - - - CG1105 "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG1105 11-Aug-17 DroID_v2017_08 "Drer\txnipa, Drer\LOC799768, Drer\zgc:110626, Drer\si:ch211-130m23.2, Drer\arrdc3a, Drer\arrdc1a, Drer\zgc:110353, Drer\txnipb, Drer\arrdc1b, Drer\arrdc2, Drer\arrdc3b" "Scer\ALY1, Scer\ALY2, Scer\CSR2, Scer\RIM8, Scer\LDB19, Scer\ART5, Scer\ROD1, Scer\ECM21, Scer\ROG3" "Cele\arrd-3, Cele\arrd-18, Cele\arrd-13, Cele\arrd-6, Cele\arrd-8, Cele\arrd-1, Cele\rnh-1.2, Cele\arrd-11, Cele\arrd-25, Cele\arrd-7, Cele\arrd-9, Cele\arrd-5, Cele\arrd-15, Cele\arrd-27, Cele\arrd-16, Cele\arrd-24, Cele\arrd-19, Cele\arrd-14, Cele\arrd-22, Cele\arrd-4, Cele\arrd-12, Cele\arrd-17, Cele\arrd-2, Cele\arrd-23" "Xtro\arrdc2, Xtro\arrdc3, Xtro\arrdc4, Xtro\txnip" "Mmus\Arrdc2, Mmus\Arrdc4, Mmus\Arrdc1, Mmus\Txnip, Mmus\Arrdc5, Mmus\Arrdc3" "Hsap\ARRDC4, Hsap\ARRDC2, Hsap\ARRDC1, Hsap\ARRDC5, Hsap\TXNIP, Hsap\ARRDC3" "viable,visible" trichogen cell FBgn0027565 CG5498 - http://flybase.org/reports/FBgn0027565 - protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with HGNC:28439 vacuolar transport ; GO:0007034 | inferred from electronic annotation with InterPro:IPR005024 endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with HGNC:28439 ESCRT III complex ; GO:0000815 | inferred from sequence or structural similarity with HGNC:28439 "BcDNA:GH08385, CG5498" IPR005024:Snf7 family CG5498 11-Aug-17 DroID_v2017_08 "Drer\chmp7, Drer\chmp4ba, Drer\chmp4bb" "Scer\SNF7, Scer\CHM7, Scer\SLK19" "Cele\vps-32.1, Cele\R12C12.5, Cele\T24B8.2, Cele\vps-32.2" Xtro\chmp7 "Mmus\Chmp4b, Mmus\Chmp4c, Mmus\Chmp7" "Hsap\CHMP4C, Hsap\CHMP4B, Hsap\CHMP7, Hsap\CHMP4A" viable FBgn0035059 CG3894 - http://flybase.org/reports/FBgn0035059 protein_coding_gene - intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001496 - "CG9197, CG3894" "IPR001496:SOCS box domain, IPR006573:Neuralized homology repeat (NHR) domain" CG3894 11-Aug-17 DroID_v2017_08 "Drer\neurl2, Drer\neurl1aa, Drer\neurl1ab" - Cele\F10D7.5 "Xtro\neurl4, Xtro\neurl2" "Mmus\Neurl1b, Mmus\Neurl1a, Mmus\Neurl2, Mmus\Neurl3" "Hsap\NEURL1B, Hsap\NEURL3, Hsap\NEURL2, Hsap\NEURL1" viable DRSC04429 I 1.807363843 -0.673355481 1.115252206 0.750739778 -0.590153373 0.21405395 FBgn0004864 hop hopscotch http://flybase.org/reports/FBgn0004864 "FBgn0001211, FBgn0003895, FBgn0022799" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | traceable author statement protein kinase activity ; GO:0004672 | NOT inferred from key residues protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with HGNC:6190 receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357" hemocyte proliferation ; GO:0035172 | traceable author statement <> innate immune response ; GO:0045087 |... biological aspect of ancestor with PANTHER:PTN000700357 <> hemopoiesis ; GO:0030097 | traceable author statement <> encapsulation of foreign target ; GO:0035010 | non-traceable author statement <> immune response ; GO:0006955 | traceable author statement <> apical constriction ; GO:0003383 |... mutant phenotype <> imaginal disc-derived leg morphogenesis ; GO:0007480 | non-traceable author statement <> tyrosine phosphorylation of STAT protein ; GO:0007260 | traceable author statement <> establishment of ommatidial planar polarity ; GO:0042067 |... mutant phenotype <> protein phosphorylation ; GO:0006468 | non-traceable author statement <> sex determination ; GO:0007530 | non-traceable author statement <> periodic partitioning ; GO:0007365 |... mutant phenotype <> hindgut morphogenesis ; GO:0007442 |... mutant phenotype <> stem cell population maintenance ; GO:0019827 |... mutant phenotype <> transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 |... biological aspect of ancestor with PANTHER:PTN000700357 <> open tracheal system development ; GO:0007424 |... mutant phenotype <> JAK-STAT cascade ; GO:0007259 | traceable author statement <> blastoderm segmentation ; GO:0007350 |... mutant phenotype <> equator specification ; GO:0045317 |... mutant phenotype <> ovarian follicle cell stalk formation ; GO:0030713 |... mutant phenotype <> regulation of JAK-STAT cascade ; GO:0046425 |... mutant phenotype <> cell proliferation ; GO:0008283 |... mutant phenotype <> mediolateral intercalation ; GO:0060031 |... mutant phenotype <> oogenesis ; GO:0048477 | traceable author statement <> ommatidial rotation ; GO:0016318 |... mutant phenotype <> cellular defense response ; GO:0006968 | non-traceable author statement <> compound eye photoreceptor cell differentiation ; GO:0001751 |... mutant phenotype <> somatic stem cell division ; GO:0048103 | traceable author statement <> locomotor rhythm ; GO:0045475 |... mutant phenotype <> primary sex determination ; GO:0007538 |... mutant phenotype <> defense response to virus ; GO:0051607 |... mutant phenotype <> humoral immune response ; GO:0006959 | traceable author statement <> regulation of embryonic cell shape ; GO:0016476 |... mutant phenotype <> lamellocyte differentiation ; GO:0035171 | traceable author statement <> JAK-STAT cascade ; GO:0007259 |... sequence or structural similarity inferred from genetic interaction with Stat92E <> STAT protein import into nucleus ; GO:0007262 | traceable author statement <> germ-line stem cell division ; GO:0042078 | traceable author statement <> blastoderm segmentation ; GO:0007350 | traceable author statement <> border follicle cell migration ; GO:0007298 |... mutant phenotype <> eye-antennal disc morphogenesis ; GO:0007455 |... mutant phenotype <> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <> long-term memory ; GO:0007616 |... mutant phenotype <> compound eye morphogenesis ; GO:0001745 |... mutant phenotype <> regulation of hemocyte differentiation ; GO:0045610 |... mutant phenotype <> hemocyte differentiation ; GO:0042386 |... mutant phenotype <> border follicle cell migration ; GO:0007298 | traceable author statement <> compound eye development ; GO:0048749 |... mutant phenotype <> larval lymph gland hemopoiesis ; GO:0035167 |... mutant phenotype <> regulation of hemocyte proliferation ; GO:0035206 |... mutant phenotype <> protein phosphorylation ; GO:0006468 | NOT inferred from key residues <> nervous system development ; GO:0007399 |... mutant phenotype <> ovarian follicle cell development ; GO:0030707 |... mutant phenotype cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 cytoplasm ; GO:0005737 | traceable author statement "Hop, hop, JAK, d-jak, Jak, Tum-1, CG1594, DmHD-160, Hop1, Dm JAK, l(1)10Be, l(1)hop, Tum, l(1)L4, 4, L4, msvl, l(1)G18, HD-160, HOP, hopscotch, jak, hop/JAK" "IPR000299:FERM domain, IPR000719:Protein kinase domain, IPR000980:SH2 domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR019749:Band 4.1 domain, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG1594 11-Aug-17 DroID_v2017_08 "Drer\ptk6b, Drer\tyk2, Drer\fynb, Drer\hck, Drer\jak2a, Drer\matk, Drer\abl1, Drer\zgc:194282, Drer\si:ch73-206d17.1, Drer\si:ch73-340m8.2, Drer\jak3, Drer\fyna, Drer\frk, Drer\ptk6a, Drer\csk, Drer\jak1, Drer\lyn, Drer\abl2, Drer\yes1, Drer\btk, Drer\txk, Drer\itk, Drer\lck, Drer\src, Drer\jak2b, Drer\fer, Drer\fes" Scer\KIN1 "Cele\F22B3.8, Cele\kin-26, Cele\C35E7.10, Cele\F59A3.8, Cele\spe-8, Cele\F57B9.8, Cele\C25A8.5, Cele\W01B6.5, Cele\T25B9.4, Cele\frk-1, Cele\C34F11.5, Cele\kin-5, Cele\T21G5.1, Cele\ZK622.1, Cele\ZC581.7, Cele\kin-14, Cele\Y43C5B.2, Cele\C18H7.4, Cele\F23C8.7, Cele\kin-24, Cele\kin-6, Cele\T06C10.3, Cele\Y116A8C.24, Cele\C55C3.4, Cele\R11E3.1, Cele\Y116A8C.38, Cele\R05H5.4" "Xtro\lyn, Xtro\fgr, Xtro\abl2, Xtro\csk, Xtro\jak2, Xtro\tec, Xtro\yes1, Xtro\lck, Xtro\fyn, Xtro\jak1, Xtro\btk, Xtro\tyk2, Xtro\jak3, Xtro\src" "Mmus\Ptk6, Mmus\Lyn, Mmus\Btk, Mmus\Fyn, Mmus\Blk, Mmus\Jak2, Mmus\Jak3, Mmus\Abl2, Mmus\Bmx, Mmus\Csk, Mmus\Tec, Mmus\Txk, Mmus\Src, Mmus\Frk, Mmus\Abl1, Mmus\Fes, Mmus\Jak1, Mmus\Srms, Mmus\Fer, Mmus\Matk, Mmus\Yes1, Mmus\Itk, Mmus\Hck, Mmus\Styk1, Mmus\Lck, Mmus\Tyk2, Mmus\Fgr" "Hsap\HCK, Hsap\JAK3, Hsap\LCK, Hsap\BTK, Hsap\FGR, Hsap\TEC, Hsap\FYN, Hsap\STYK1, Hsap\TXK, Hsap\SRMS, Hsap\FER, Hsap\ABL1, Hsap\JAK2, Hsap\TYK2, Hsap\BLK, Hsap\JAK1, Hsap\LYN, Hsap\PTK6, Hsap\SRC, Hsap\YES1, Hsap\INSL3, Hsap\ITK, Hsap\BMX, Hsap\FRK, Hsap\FES, Hsap\ABL2, Hsap\CSK, Hsap\MATK" " embryonic stage | early , embryonic stage -- adult stage " "lethal,recessive,heat sensitive,female sterile,visible,planar polarity defective,maternal effect,polyphasic,male sterile,memory defective,RU486 conditional,lethal - all die before end of larval stage,some die during larval stage,dominant,viable,rescuable maternal effect,wild-type,cell non-autonomous,somatic clone,cell autonomous,cell shape defective,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,immune response defective,partially,fertile,female,reduced,locomotor rhythm defective,partially lethal - majority die,melanotic mass phenotype,tumorigenic,semidominant,increased cell number,hyperplasia,neuroanatomy defective" "eye,ommatidium,interommatidial bristle,eye photoreceptor cell,testis,axoneme,wing vein,ectopic,polar follicle cell,supernumerary,egg chamber,pole cell,maternal effect,gonad,embryonic hindgut,germline clone,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,mesothoracic ventral denticle belt,embryonic abdominal segment 5,non-rescuable maternal effect,embryonic abdominal segment 4,presumptive embryonic/larval tracheal system,embryonic head,telson,border follicle cell,somatic clone,nurse follicle cell,spermatogonium,male germline stem cell,embryonic/larval proventriculus,denticle belt,rescuable maternal effect,tracheal branch primordium,dorsal trunk primordium,cell non-autonomous,eye equator,ectoderm,centripetally migrating follicle cell,oocyte associated follicle cell,follicle cell,posterior,interfollicle cell,cyst progenitor cell,embryonic/larval hemocyte,embryonic/larval lymph gland,gastric caecum,embryonic/larval foregut,embryonic/larval midgut,embryonic/larval hindgut,embryonic/larval brain,embryonic/larval anterior spiracle,embryonic/larval fat body,melanotic mass,segment,embryonic abdominal segment,filzkorper,plasmatocyte,hemocyte,lamellocyte,hindgut,hindgut & nucleus,peripheral nervous system,axon,crystal cell,podocyte,heat sensitive,precursor,abdomen,tracheal pit,ovary,hindgut & nucleushs.PB,axonhs.PB,wing,scutellum,scutum,larval outer optic anlage,male germline cell" FBgn0029688 lva lava lamp http://flybase.org/reports/FBgn0029688 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VJE5 spectrin binding ; GO:0030507 | traceable author statement microtubule binding ; GO:0008017 | inferred from direct assay cellularization ; GO:0007349 | traceable author statement neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype establishment of Golgi localization ; GO:0051683 | inferred from mutant phenotype positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype cellularization ; GO:0007349 | non-traceable author statement Golgi apparatus ; GO:0005794 | traceable author statement Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi cis cisterna ; GO:0000137 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay Golgi apparatus ; GO:0005794 | "Lva, lava, CG6450, LVA, CG#6450, ABP2, lva, lvl, Lava, Lvl, LVA_DROME" - CG6450 11-Aug-17 DroID_v2017_08 "Drer\golgb1, Drer\cenpe, Drer\znf185, Drer\golga4" "Scer\MLP2, Scer\USO1, Scer\MLP1" "Cele\anc-1, Cele\che-10, Cele\F59A2.2, Cele\golg-4" - "Mmus\Golga4, Mmus\Cenpf, Mmus\Cenpe, Mmus\Tnip2, Mmus\Golgb1" "Hsap\CEP250, Hsap\GOLGA4, Hsap\CENPE, Hsap\TNIP2, Hsap\GOLGB1, Hsap\CENPF" "neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "Golgi apparatus & dendritic arborising neuron477,dendrite & dendritic arborising neuron477,Golgi apparatus & dendritic arborising neuron109(2)80,dendrite & dendritic arborising neuron109(2)80" DRSC18403 E 1.037045854 0.385096231 1.069402125 -1.785426693 -0.362481296 -0.242524481 FBgn0000662 fl(2)d female lethal d http://flybase.org/reports/FBgn0000662 FBgn0028976 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KIF8 inferred from physical interaction with UniProtKB:Q9W1R5 protein binding ; GO:0005515 | inferred from physical interaction with so "female germ-line sex determination ; GO:0019099 | non-traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype sex determination ; GO:0007530 | inferred from physical interaction with Sxl RNA splicing, via transesterification reactions ; GO:0000375 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype mRNA methylation ; GO:0080009 | inferred from biological aspect of ancestor with PANTHER:PTN000390848 primary sex determination, soma ; GO:0007539 | non-traceable author statement heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from physical interaction with vir inferred from physical interaction with Sxl" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement "v(2)k16105, CG6315, fl(2)d, Fl(2)d" "IPR033757:Pre-mRNA-splicing regulator WTAP, IPR029732:WTAP/Mum2 family" CG6315 11-Aug-17 DroID_v2017_08 Drer\wtap - - Xtro\wtap Mmus\Wtap Hsap\WTAP " larval stage , embryonic stage , adult stage | female , adult stage | male " " adult stage | female , embryonic stage , adult stage | male , larval stage | female , larval stage | male " " adult head

,

, ovary

" "visible,recessive,lethal,wild-type,female,heat sensitive,partially lethal - majority die,male,partially,female sterile,lethal - all die before end of larval stage,some die during larval stage,sex-determination defective,somatic clone,some die during pupal stage" "eye,somatic clone,chaeta,supernumerary,mesothoracic tergum,eye photoreceptor cell,rhabdomere of eye photoreceptor cell" FBgn0004511 dy dusky http://flybase.org/reports/FBgn0004511 FBgn0000525 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inferred from genetic interaction with m cell morphogenesis ; GO:0000902 | inferred from genetic interaction with m integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "ala, dy, dy1, CG9355" "IPR001507:Zona pellucida domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG9355 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-103f14.3, Drer\zmp:0000001031, Drer\zgc:153932, Drer\si:ch211-229d2.5" - "Cele\cutl-15, Cele\cutl-14, Cele\ram-5, Cele\cutl-20, Cele\cut-4, Cele\cut-3, Cele\cutl-5, Cele\cutl-6, Cele\cutl-7, Cele\cutl-16, Cele\cutl-28, Cele\cutl-22, Cele\cutl-11, Cele\T01D1.8, Cele\cutl-8, Cele\cutl-12, Cele\cut-6, Cele\cutl-4, Cele\cut-5, Cele\cutl-9, Cele\cutl-29, Cele\cutl-26, Cele\cutl-2, Cele\dpy-1, Cele\cutl-3, Cele\cutl-19, Cele\cutl-1, Cele\cut-1, Cele\cutl-13, Cele\cutl-24, Cele\cutl-25, Cele\F46G11.6, Cele\cutl-10" "Xtro\MGC89178, Xtro\thdl18, Xtro\thdl17" - - " embryonic stage , pupal stage , larval stage | second instar , larval stage | first instar " "viable,fertile,visible,recessive,male fertile,female fertile,heat sensitive,cell autonomous,somatic clone,lethal,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "wing,heat sensitive,cell autonomous,somatic clone,antenna,microchaeta,chaeta" FBgn0046124 E(To)10 E(To)10 http://flybase.org/reports/FBgn0046124 gene - - - E(To)10 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0001316 klar klarsicht http://flybase.org/reports/FBgn0001316 FBgn0002650 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Lsd-2 protein binding ; GO:0005515 | inferred from physical interaction with Msp300 kinesin binding ; GO:0019894 | inferred from direct assay "lipid particle transport along microtubule ; GO:0031887 | inferred from mutant phenotype nuclear migration ; GO:0007097 | inferred from mutant phenotype nucleus localization ; GO:0051647 | inferred from genetic interaction with Msp300 tube morphogenesis ; GO:0035239 | inferred from mutant phenotype nucleus organization ; GO:0006997 | inferred from genetic interaction with Msp300 compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype regulation of intracellular transport ; GO:0032386 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype negative regulation of pole plasm oskar mRNA localization ; GO:0045855 | inferred from mutant phenotype lipid transport ; GO:0006869 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype membrane organization ; GO:0061024 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype microtubule anchoring ; GO:0034453 | inferred from genetic interaction with klar" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012315 perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytoplasmic microtubule ; GO:0005881 | colocalizes_with inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay nuclear outer membrane ; GO:0005640 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay lipid particle ; GO:0005811 | colocalizes_with inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay nuclear envelope ; GO:0005635 | colocalizes_with inferred from direct assay "kls, Klar, CG17046, marb, klar" IPR012315:KASH domain CG17046 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | third instar , embryonic stage | late " " eye disc

, adult salivary gland primordium

dorsal & posterior , morphogenetic furrow | posterior to

" larval stage | third instar photoreceptor

"locomotor behavior defective,flightless,viable,fertile,visible,recessive,female semi-sterile,wild-type,partially lethal - majority die,some die during pupal stage,neuroanatomy defective" "embryonic/larval muscle system,A1-7 dorsal oblique muscle 1,A1-7 dorsal oblique muscle 2,A1-7 dorsal acute muscle 1,A1-7 dorsal acute muscle 2,oocyte nucleus,photoreceptor cell,eye,rhabdomereemc-E12),photoreceptor cell & nucleusemc-E12),rhabdomere,photoreceptor cell & nucleus,retina,interommatidial bristle,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R8,nucleus & eye photoreceptor cell & eye disc,nucleus & cone cell & eye disc,cone cell,eye photoreceptor cell,lipid particle,ommatidium,presumptive embryonic salivary gland,eye disc,tracheal system,scutum & macrochaeta,eye disc & nucleus | ectopic,rhabdomere & nucleus,chaeta,supernumerary,neurite | pharate adult stage" FBgn0004656 fs(1)h female sterile (1) homeotic http://flybase.org/reports/FBgn0004656 "FBgn0000809, FBgn0001447, FBgn0025246, FBgn0025884, FBgn0040137, FBgn0040199" protein_coding_gene - "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from sequence or structural similarity with HGNC:13575 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "l(1)7Da, fsh, clone 1.81, rnc, fst(1)h, fs(1)1456, N72, fs(1)M16, l(1)G0093, l(1)G0495, anon-EST:fe1G2, fs(1)R10.4, fs(1)26/26A, anon-EST:Liang-1.81, CG2252, fs(1)h, Fs(1)h, Fs(1)hS, Fs(1)hL, ORE-1, Fsh, Fs(1)h-L, FSH" "IPR018359:Bromodomain, conserved site, IPR001487:Bromodomain, IPR027353:NET domain, IPR031354:Bromodomain protein 4, C-terminal" CG2252 11-Aug-17 DroID_v2017_08 "Drer\brd3b, Drer\brd2b, Drer\brd2a, Drer\brdt, Drer\brd3a, Drer\brd4" "Scer\BDF2, Scer\SPT7, Scer\BDF1" "Cele\F59F5.7, Cele\baz-2, Cele\F13C5.2, Cele\bet-2, Cele\bet-1" "Xtro\brd2, Xtro\brd4, Xtro\brdt, Xtro\brd3" "Mmus\Brdt, Mmus\Brd2, Mmus\Brd4, Mmus\Brd3, Mmus\Cecr2, Mmus\Baz1a" "Hsap\BRDT, Hsap\BAZ1A, Hsap\BAZ2B, Hsap\CECR2, Hsap\BRD4, Hsap\CCDC127, Hsap\BRD2, Hsap\BRD3" "viable,fertile,lethal,recessive,lethal - all die before end of larval stage,male,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,heat sensitive,maternal effect,cell lethal,germline clone,rescuable maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,partially" "hypostomal sclerite,mouth hooks,embryonic head,abdominal segment 2,maternal effect,heat sensitive,filzkorper,larval head,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,egg,metathoracic segment" DRSC29017 K -0.156750498 0.260578013 0.052372009 0.336929708 3.384193892 3.931450316 FBgn0016675 Lectin-galC1 Galactose-specific C-type lectin http://flybase.org/reports/FBgn0016675 - protein_coding_gene galactose binding ; GO:0005534 | inferred from direct assay receptor activity ; GO:0004872 | traceable author statement calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from direct assay induction of bacterial agglutination ; GO:0043152 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model inferred from direct assay "AC007082a, Dgal-1, CG9976, Lectin-galC1, DL1, Lecti-galC1, lectin-galC1" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG9976 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-26c10.5, Drer\zmp:0000000924, Drer\colec11, Drer\selp, Drer\si:ch73-111e15.1, Drer\LOC101882781, Drer\LOC101884526, Drer\si:dkey-83f18.10, Drer\si:ch211-193e13.5, Drer\cd209, Drer\zmp:0000000937, Drer\si:ch73-122g19.1" - "Cele\clec-28, Cele\clec-38, Cele\clec-7, Cele\clec-31, Cele\clec-17, Cele\clec-39, Cele\clec-9, Cele\clec-4, Cele\clec-26, Cele\clec-149, Cele\clec-45" - "Mmus\Clec4g, Mmus\Cd209c, Mmus\Clec12b, Mmus\Sftpd, Mmus\Cd209a, Mmus\Cd209b, Mmus\Sell, Mmus\Clec4e, Mmus\Clec9a, Mmus\Gm156, Mmus\Cd209e" "Hsap\CLEC6A, Hsap\COLEC10, Hsap\SFTPA2, Hsap\CLEC4D, Hsap\CLEC4E" " adult stage , pupal stage , larval stage | third instar " viable FBgn0038870 Oga O-GlcNAcase http://flybase.org/reports/FBgn0038870 protein_coding_gene beta-N-acetylglucosaminidase activity ; GO:0016231 | inferred from biological aspect of ancestor with PANTHER:PTN001775926 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype N-glycan processing ; GO:0006491 | inferred from direct assay protein O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from mutant phenotype - "Oga, OGA, CG5871, GlcNAcase, MGEA5, oga" "IPR011496:Beta-N-acetylglucosaminidase, IPR016181:Acyl-CoA N-acyltransferase, IPR017853:Glycoside hydrolase superfamily" CG5871 11-Aug-17 DroID_v2017_08 "Drer\mgea5l, Drer\zmp:0000000799, Drer\mgea5" Scer\ICP55 Cele\oga-1 Xtro\mgea5 Mmus\Mgea5 Hsap\MGEA5 "locomotor rhythm defective,large body,viable" FBgn0261698 SLO2 slowpoke 2 http://flybase.org/reports/FBgn0261698 protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000002873 calcium-activated potassium channel activity ; GO:0015269 | inferred from sequence or structural similarity with slo calcium-activated potassium channel activity ; GO:0015269 | inferred from biological aspect of ancestor with PANTHER:PTN000002873 intracellular sodium activated potassium channel activity ; GO:0005228 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from sequence or structural similarity with slo neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype potassium ion transmembrane transport ; GO:0071805 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with slo voltage-gated potassium channel complex ; GO:0008076 | inferred from biological aspect of ancestor with PANTHER:PTN000002873 "CG12900/CG34363, CG42732, CG34363, CG12904, CG12901, CG12899, CG12897, Dm_2R:24438, Dm_2R:24301, Slack, SLO2, dSLO2" "IPR013099:Potassium channel domain, IPR003929:Potassium channel, BK, alpha subunit" CG42732 11-Aug-17 DroID_v2017_08 "Drer\kcnt1, Drer\si:dkey-21e5.1, Drer\kcnt2, Drer\LOC565691" - Cele\slo-2 Xtro\kcnt2 "Mmus\Kcnt1, Mmus\Kcnt2" "Hsap\KCNT1, Hsap\KCNT2" DRSC23225 K 0.044615677 1.771277296 FBgn0030914 CG6106 - http://flybase.org/reports/FBgn0030914 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR017593 cobalt ion binding ; GO:0050897 | inferred from electronic annotation with InterPro:IPR017593 allantoinase activity ; GO:0004038 | inferred from biological aspect of ancestor with PANTHER:PTN000909483 allantoin catabolic process ; GO:0000256 | inferred from electronic annotation with InterPro:IPR017593 purine nucleobase catabolic process ; GO:0006145 | inferred from biological aspect of ancestor with PANTHER:PTN000909483 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000909483 CG6106 "IPR011059:Metal-dependent hydrolase, composite domain, IPR017593:Allantoinase, IPR006680:Amidohydrolase-related, IPR032466:Metal-dependent hydrolase" CG6106 11-Aug-17 DroID_v2017_08 "Drer\dpysl4, Drer\dpysl2a, Drer\dpys, Drer\zgc:103559, Drer\dpysl5b" Scer\DAL1 "Cele\unc-33, Cele\dhp-2" "Xtro\crmp1, Xtro\dpys, Xtro\dpysl3, Xtro\LOC100498039, Xtro\dpysl5, Xtro\dpysl4" "Mmus\Crmp1, Mmus\Dpysl3, Mmus\Dpysl4, Mmus\Dpysl5, Mmus\Dpys, Mmus\Dpysl2" "Hsap\CRMP1, Hsap\DPYSL3, Hsap\DPYSL5, Hsap\DPYSL4, Hsap\DPYSL2, Hsap\DPYS" viable FBgn0085397 Fili Fish-lips http://flybase.org/reports/FBgn0085397 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from biological aspect of ancestor with PANTHER:PTN000689992 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 proteinaceous extracellular matrix ; GO:0005578 | inferred from biological aspect of ancestor with PANTHER:PTN001224703 "CG34368, CT32855, CG13487, CT13464, CG4054, Fili" "IPR003591:Leucine-rich repeat, typical subtype, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG34368 11-Aug-17 DroID_v2017_08 "Drer\lingo4a, Drer\flrt1a, Drer\flrt1b, Drer\lingo2b, Drer\lingo2a, Drer\LOC100151059, Drer\lingo4b, Drer\si:dkey-182i3.11, Drer\lingo1b, Drer\si:dkey-1j5.4, Drer\flrt3, Drer\lingo1a, Drer\lingo3a" - "Cele\let-4, Cele\lron-11" "Xtro\lingo1, Xtro\flrt3, Xtro\lingo4, Xtro\tril, Xtro\flrt1, Xtro\lingo2, Xtro\LOC100488097" "Mmus\Lingo3, Mmus\Flrt1, Mmus\Lingo4, Mmus\Tril, Mmus\Lingo1, Mmus\Flrt3, Mmus\Lingo2" "Hsap\FLRT1, Hsap\LINGO1, Hsap\LINGO2, Hsap\LINGO3, Hsap\FLRT3, Hsap\LINGO4, Hsap\LRRC70" FBgn0261053 Cad86C Cadherin 86C http://flybase.org/reports/FBgn0261053 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model regulation of cell shape ; GO:0008360 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR030326 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity subapical complex ; GO:0035003 | inferred from direct assay "Cad86C, CG42601, CT14654, CG31425, CG31393, CG33112, CG4509, DCad86C, CT15041, BcDNA:LP07955, CG4655" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR030326:Cadherin-related family member 5, IPR020894:Cadherin conserved site" CG42601 11-Aug-17 DroID_v2017_08 "Drer\cdhr2, Drer\cdhr1a" - "Cele\cdh-9, Cele\cdh-10" "Xtro\cdhr1, Xtro\cdhr2" "Mmus\Cdhr5, Mmus\Cdhr1, Mmus\Cdhr2, Mmus\Cdh18" "Hsap\CDH18, Hsap\CDHR2, Hsap\CDHR1, Hsap\CDHR5" FBgn0038307 mRpS10 mitochondrial ribosomal protein S10 http://flybase.org/reports/FBgn0038307 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82664 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82664 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82664 "MRP-S10, CG4247, MrpS10, BcDNA:GM25447, mRpS10" IPR027486:Ribosomal protein S10 domain CG4247 11-Aug-17 DroID_v2017_08 Drer\mrps10 Scer\RSM10 Cele\mrps-10 Xtro\mrps10 Mmus\Mrps10 Hsap\MRPS10 FBgn0027364 Six4 Six4 http://flybase.org/reports/FBgn0027364 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 fat body development ; GO:0007503 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype" - "six4, six4/5, D-Six4, Dsix4, CG3871, Six4, DSix4, D-six4" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR031701:Homeobox protein SIX1, N-terminal SD domain" CG3871 11-Aug-17 DroID_v2017_08 "Drer\six9, Drer\six2b, Drer\six2a, Drer\six3a, Drer\six4b, Drer\six7, Drer\six3b, Drer\six5, Drer\six6b, Drer\six1b, Drer\six6a, Drer\six4a, Drer\six1a" - "Cele\ceh-88, Cele\ceh-32, Cele\ceh-33, Cele\ceh-34, Cele\unc-39" "Xtro\six3, Xtro\six4, Xtro\six6, Xtro\six2, Xtro\six1" "Mmus\Six6, Mmus\Six1, Mmus\Six5, Mmus\Six4, Mmus\Six3, Mmus\Six2" "Hsap\SIX6, Hsap\SIX5, Hsap\SIX3, Hsap\SIX2, Hsap\SIX1, Hsap\SIX4" " embryonic stage , embryonic stage | stage 15 , embryonic stage | stage 9,10 " " embryonic brain

, procephalic segment

, organism | 80-90% egg length

, gonad

, mesoderm

, ventral nerve cord

" "viable,fertile,lethal,partially,recessive,increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage" "gonad,testis,ovary,crop,embryonic/larval muscle system,adult abdomen,germline cell,fat body/gonad primordium,embryonic somatic muscle,segment border muscle,ventral oblique muscle,ventral longitudinal muscle,border follicle cell,ectopic,somatic clone,eye" DRSC29889 K -1.44745241 0.288303436 -0.546391553 -0.127353177 -0.186707552 -1.508210064 FBgn0058178 CG40178 - http://flybase.org/reports/FBgn0058178 protein_coding_gene - cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001531327 "CG40178, CG40178/CG41283" "IPR018253:DnaJ domain, conserved site, IPR001623:DnaJ domain, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain" CG40178 11-Aug-17 DroID_v2017_08 "Drer\dnajc16l, Drer\dnajc16, Drer\dnaja1, Drer\dnaja3b, Drer\dnajc24, Drer\dnaja3a" "Scer\YDJ1, Scer\MDJ1" "Cele\dnj-8, Cele\dnj-3, Cele\dnj-14" "Xtro\dnajc24, Xtro\dnajc16" "Mmus\Dnaja4, Mmus\Dnajc24, Mmus\Dnajc16, Mmus\Dnaja1, Mmus\Dnaja3" "Hsap\DNAJC24, Hsap\DNAJA4, Hsap\DNAJC16, Hsap\DNAJA3, Hsap\DNAJA1" FBgn0032195 CG4908 - http://flybase.org/reports/FBgn0032195 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960" "mitochondrial respiratory chain complex III assembly ; GO:0034551 | inferred from electronic annotation with InterPro:IPR014851, InterPro:IPR027243" - CG4908 "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014851:BCS1, N-terminal, IPR027243:Mitochondrial chaperone BCS1" CG4908 11-Aug-17 DroID_v2017_08 Drer\bcs1l Scer\BCS1 Cele\bcs-1 Xtro\bcs1l Mmus\Bcs1l Hsap\BCS1L viable FBgn0010238 Lac Lachesin http://flybase.org/reports/FBgn0010238 FBgn0021933 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from direct assay "maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay open tracheal system development ; GO:0007424 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from expression pattern inferred from mutant phenotype morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay septate junction ; GO:0005918 | inferred from direct assay "Lac, bulb, lac, CT24921, l(2)k11012b, l(2)k11012, CG12369" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG12369 11-Aug-17 DroID_v2017_08 "Drer\esama, Drer\f11r.2, Drer\opcml, Drer\si:ch211-264f5.6, Drer\zgc:153073, Drer\cxcr3.1, Drer\cxadr, Drer\mxra8a, Drer\LOC100151468, Drer\si:ch1073-59l16.1, Drer\vsig8a, Drer\zgc:198329, Drer\si:ch211-215e19.3, Drer\negr1, Drer\si:dkey-15j16.3, Drer\jam3a, Drer\si:ch211-264f5.2, Drer\si:ch211-9d9.7, Drer\f11r.1, Drer\esamb, Drer\mxra8b, Drer\jam2b, Drer\si:dkey-250k15.10, Drer\pigr, Drer\si:zfos-1011f11.1, Drer\hepacam2, Drer\vsig8b, Drer\igsf11, Drer\ntm, Drer\jam3b, Drer\pigrl2.3, Drer\jam2a, Drer\zgc:110372, Drer\gpa33, Drer\pigrl4.2, Drer\si:dkey-65b12.12" - "Cele\zig-1, Cele\zig-10, Cele\zig-7, Cele\zig-11, Cele\rig-5" "Xtro\negr1, Xtro\hepacam2, Xtro\icam5" "Mmus\Vsig2, Mmus\Gm1123, Mmus\Vsig8, Mmus\Clmp, Mmus\Igsf5, Mmus\Cntn5, Mmus\Jam2, Mmus\Vsir, Mmus\Hepacam2, Mmus\Esam, Mmus\Vsig1, Mmus\Negr1, Mmus\Igsf11, Mmus\Mxra8, Mmus\Gpa33, Mmus\Jam3, Mmus\F11r, Mmus\Cxadr" "Hsap\CEACAM1, Hsap\ESAM, Hsap\VSIG8, Hsap\PSG11, Hsap\CEACAM8, Hsap\F11R, Hsap\IGSF5, Hsap\IGSF11, Hsap\C1orf204, Hsap\C10orf54, Hsap\VSIG1, Hsap\GPA33, Hsap\CXADR, Hsap\MXRA8, Hsap\CLMP, Hsap\VSIG2, Hsap\JAM2, Hsap\HEPACAM2, Hsap\PSG2, Hsap\PSG5, Hsap\CEACAM6, Hsap\NEGR1, Hsap\JAM3" "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal - all die before end of pupal stage,some die during pupal stage" "presumptive embryonic/larval tracheal system,tracheocyte,dorsal group branch precursor,lateral group branch precursor,presumptive embryonic salivary gland,dorsal trunk primordium,septate junction,PNS glial cell,CNS glial cell,taenidial fold,embryonic/larval dorsal trunk,embryonic/larval transverse connective,embryonic/larval tracheal system" FBgn0011708 Syx5 Syntaxin 5 http://flybase.org/reports/FBgn0011708 "FBgn0001996, FBgn0015339, FBgn0020602" protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:Q24509 SNARE binding ; GO:0000149 | inferred from sequence model SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNAP receptor activity ; GO:0005484 | inferred from physical interaction with αSnap SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000461791 vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 cell morphogenesis ; GO:0000902 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | non-traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of mitotic cell cycle ; GO:0045930 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 Golgi organization ; GO:0007030 | inferred from mutant phenotype synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity cellular copper ion homeostasis ; GO:0006878 | inferred from mutant phenotype copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype vesicle docking ; GO:0048278 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement spermatogenesis ; GO:0007283 | inferred from mutant phenotype regulation of cell diameter ; GO:0060305 | inferred from mutant phenotype cis-Golgi network ; GO:0005801 | inferred from direct assay Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000461791 SNARE complex ; GO:0031201 | inferred from sequence model SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q08851 endomembrane system ; GO:0012505 | inferred from direct assay Golgi membrane ; GO:0000139 | inferred from sequence or structural similarity with UniProtKB:Q08851 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 "Syntaxin 5, Synx5, Syx5A, dSed5p, syx5, Sed5, dSyx5, dsed5, CG4214, DmSyx5, sed5, l(2)35Ff, SED5, BG:DS02740.12, II, dSed5, anon-35Fd, anon-35Fb, Syx5, Syx, SYN5, syn5" "IPR000727:Target SNARE coiled-coil homology domain, IPR006012:Syntaxin/epimorphin, conserved site, IPR010989:SNARE" CG4214 11-Aug-17 DroID_v2017_08 "Drer\stx5al, Drer\stx5a" Scer\SED5 Cele\syx-5 Xtro\stx5 Mmus\Stx5a Hsap\STX5 " adult stage , embryonic stage " "lethal,recessive,visible,partially lethal - majority die,cytokinesis defective,male sterile,wild-type,chemical resistant,dominant" "adult cuticle,scutellum,chaeta,spermatozoon,testis,Nebenkern,embryonic/larval salivary gland,Golgi stack,endoplasmic reticulum,thorax" DRSC03432 IEK -0.255476752 2.623973357 1.555155686 -1.557426759 -2.272766512 -1.0368977 FBgn0039066 EloA Elongin A http://flybase.org/reports/FBgn0039066 protein_coding_gene - imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype inferred from genetic interaction with corto positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from sequence or structural similarity with UniProtKB:Q63187 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010684 elongin complex ; GO:0070449 | inferred from sequence or structural similarity with RGD:3827 elongin complex ; GO:0070449 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | colocalizes_with inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from sequence or structural similarity with UniProtKB:Q63187 nucleus ; GO:0005634 | inferred from direct assay "dEloA, CG6755, EloA, Elo-A" "IPR010684:RNA polymerase II transcription factor SIII, subunit A, IPR017923:Transcription factor IIS, N-terminal, IPR003617:Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type" CG6755 11-Aug-17 DroID_v2017_08 "Drer\zgc:152986, Drer\zgc:55573" Scer\ELA1 "Cele\R03D7.4, Cele\F28A10.4, Cele\K09F5.1, Cele\T23E1.3" Xtro\tceb3 Mmus\Eloa "Hsap\TCEB3B, Hsap\TCEB3CL, Hsap\TCEB3C, Hsap\TCEB3, Hsap\TCEB3CL2" "lethal - all die before end of pupal stage,some die during pupal stage,lethal,visible,somatic clone,viable" "wing vein,ectopic,wing margin,somatic clone" DRSC16109 EK 0.626121923 0.755874923 1.59185246 0.976145324 2.299562316 0.745544605 FBgn0037130 Syn1 Syntrophin-like 1 http://flybase.org/reports/FBgn0037130 protein_coding_gene structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC:11167 inferred from sequence or structural similarity with HGNC:11168 inferred from sequence or structural similarity with HGNC:11169 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity locomotion ; GO:0040011 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from genetic interaction with Nsf2 syntrophin complex ; GO:0016013 | inferred from sequence or structural similarity with HGNC:11167 inferred from sequence or structural similarity with HGNC:11168 inferred from sequence or structural similarity with HGNC:11169 syntrophin complex ; GO:0016013 | inferred from sequence or structural similarity "CG7152, CG7151, DmSYN-1, Syn1" "IPR001478:PDZ domain, IPR001849:Pleckstrin homology domain, IPR015482:Syntrophin, IPR011993:PH domain-like, IPR031072:Syntrophin-1" CG7152 11-Aug-17 DroID_v2017_08 "Drer\sntb1, Drer\il16, Drer\slc9a3r1, Drer\grid2ipa, Drer\pdzd7b, Drer\lnx1, Drer\snta1, Drer\grip1, Drer\sntb2, Drer\dlg5a, Drer\grip2b, Drer\si:dkey-92i15.4, Drer\pard3bb, Drer\inadl" - Cele\stn-1 "Xtro\lnx1, Xtro\grip2, Xtro\dlg5, Xtro\grid2ip, Xtro\sntb1, Xtro\grip1, Xtro\snta1" "Mmus\Mpdz, Mmus\Grasp, Mmus\Pdzd11, Mmus\Ush1c, Mmus\Patj, Mmus\Pdzph1, Mmus\Pdzd2, Mmus\Lnx1, Mmus\Sntb1, Mmus\Sntb2, Mmus\Dlg5, Mmus\Grid2ip, Mmus\Grip1, Mmus\Snta1, Mmus\Il16, Mmus\Grip2" "Hsap\GRIP1, Hsap\IL16, Hsap\FRMPD2, Hsap\GRASP, Hsap\SNTB1, Hsap\USH1C, Hsap\SNTA1, Hsap\SNTB2, Hsap\PATJ, Hsap\DLG5, Hsap\PDZD2, Hsap\GRID2IP, Hsap\PARD3B, Hsap\LNX1, Hsap\MPDZ" "partially lethal - majority die,song defective,viable" FBgn0003390 shf shifted http://flybase.org/reports/FBgn0003390 FBgn0029901 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q02936 positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | NOT inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:P18502 smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | inferred from direct assay "D-Wif, DmWif, shf-ov, CT10514, CG3135, shf, DmWIF, Shf, CG3134" "IPR000742:EGF-like domain, IPR003306:WIF domain, IPR013032:EGF-like, conserved site, IPR013309:Wnt inhibitory factor (WIF)-1" CG3135 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-246m6.5, Drer\si:dkey-30e9.7, Drer\wif1" - "Cele\dsl-3, Cele\dsl-4, Cele\dsl-5" "Xtro\vwde, Xtro\nell2, Xtro\wif1, Xtro\tenm2" "Mmus\Wif1, Mmus\Vwde" "Hsap\WIF1, Hsap\VWDE" "viable,partially lethal - majority die,recessive,female sterile,small body,partially lethal - majority live,sterile,reduced,lethal - all die before end of embryonic stage,some die during embryonic stage,fertile,semi-sterile,visible,poor" "wing,1st posterior cell,wing vein L3,scutellum,eye,scutellar bristle,wing vein L4,metathoracic leg,anterior crossvein,posterior scutellar bristle,denticle belt,wing vein,wing basal cell 1,postvertical bristle,ommatidium" FBgn0000385 ctl coatless http://flybase.org/reports/FBgn0000385 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ctl - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0030103 Obp8a Odorant-binding protein 8a http://flybase.org/reports/FBgn0030103 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "8a, CG12665, Obp8a, DmelObp8a" IPR006170:Pheromone/general odorant binding protein CG12665 11-Aug-17 DroID_v2017_08 - - - - - - viable FBgn0022361 Pur-alpha Purine-rich binding protein-alpha http://flybase.org/reports/FBgn0022361 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA binding ; GO:0003723 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from direct assay DNA binding ; GO:0003677 | inferred from sequence or structural similarity with HGNC:9701 regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay messenger ribonucleoprotein complex ; GO:1990124 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Pur-alpha, pur-alpha, PURalpha, CG1507, Pur-a, Pur alpha, dPur alpha, purA" IPR006628:Purine-rich element binding protein family CG1507 11-Aug-17 DroID_v2017_08 "Drer\purbb, Drer\purg, Drer\LOC564840, Drer\puraa, Drer\purba" - "Cele\plp-2, Cele\plp-1" "Xtro\purg, Xtro\pura, Xtro\purb" "Mmus\Purg, Mmus\Purb, Mmus\Pura" "Hsap\PURG, Hsap\PURA, Hsap\PURB" "lethal,male limited,viable" FBgn0038853 RhoGAP93B Rho GTPase activating protein at 93B http://flybase.org/reports/FBgn0038853 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from direct assay GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with SGD:S000000957 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with robo1 axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with Sos axon guidance ; GO:0007411 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay" cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000857 cytoplasm ; GO:0005737 | inferred from direct assay "CG3421, Vilse, CrGAP, vilse, RhoGAP93B, RhoGAP" "IPR000198:Rho GTPase-activating protein domain, IPR000857:MyTH4 domain, IPR001202:WW domain, IPR008936:Rho GTPase activation protein" CG3421 11-Aug-17 DroID_v2017_08 "Drer\arhgap24, Drer\si:ch211-218g4.2, Drer\arhgap39, Drer\zgc:92107" - "Cele\Y92H12BL.4, Cele\pac-1, Cele\Y92H12BM.1" Xtro\arhgap25 "Mmus\Arhgap24, Mmus\Arhgap25, Mmus\Arhgap39" "Hsap\ARHGAP25, Hsap\ARHGAP39, Hsap\ARHGAP24" "viable,fertile,lethal,recessive,germline clone,visible" "ganglionic branch primordium,longitudinal connective,eye,medial longitudinal fascicle,ventral midline,commissure" FBgn0069113 mus217 mutagen-sensitive 217 http://flybase.org/reports/FBgn0069113 gene - - - mus217 - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,chemical sensitive" FBgn0023542 Nmd3 Nonsense-mediated mRNA 3 http://flybase.org/reports/FBgn0023542 FBgn0014089 protein_coding_gene ribosomal large subunit binding ; GO:0043023 | inferred from biological aspect of ancestor with PANTHER:PTN000978434 cellular response to starvation ; GO:0009267 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal large subunit export from nucleus ; GO:0000055 | inferred from biological aspect of ancestor with PANTHER:PTN000978434 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000978434 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000978434 "EG:152A3.1, CG3460, TcD12, II, TcD13, dNmd3, anon-2Eb, Nmd3" IPR007064:NMD3 CG3460 11-Aug-17 DroID_v2017_08 Drer\nmd3 Scer\NMD3 Cele\T25G3.3 Xtro\nmd3 Mmus\Nmd3 Hsap\NMD3 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0004648 svr silver http://flybase.org/reports/FBgn0004648 "FBgn0000268, FBgn0000521, FBgn0003652, FBgn0012063, FBgn0029527, FBgn0052818" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 carboxypeptidase activity ; GO:0004180 | inferred from mutant phenotype metallocarboxypeptidase activity ; GO:0004181 | inferred from direct assay carboxypeptidase activity ; GO:0004180 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype peptide metabolic process ; GO:0006518 | inferred from biological aspect of ancestor with PANTHER:PTN000163972 negative regulation of protein phosphorylation ; GO:0001933 | inferred from mutant phenotype protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000163972 positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000163972 "svr, CG4122, CPD, EP(X)0356, EG:171D11.3, CG18503, CP, slv, poi, l(1)1Bd, dwp, cc, CpepE, CG32818, CypD" "IPR000834:Peptidase M14, carboxypeptidase A, IPR008969:Carboxypeptidase-like, regulatory domain, IPR034241:Carboxypeptidase D, carboxypeptidase-like domain 1" CG4122 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-459j12.1, Drer\cpn1, Drer\cpxm1a, Drer\cpe, Drer\cpdb, Drer\aebp1, Drer\cpm, Drer\cpda" - "Cele\egl-21, Cele\suro-1, Cele\cpd-2, Cele\cpd-1" "Xtro\cpz, Xtro\cpe, Xtro\cpxm2, Xtro\ebf4, Xtro\cpm, Xtro\cpn1, Xtro\cpd" "Mmus\Cpz, Mmus\Cpd, Mmus\Cpn1, Mmus\Cpe, Mmus\Cpm, Mmus\Cpxm1, Mmus\Aebp1, Mmus\Cpxm2" "Hsap\CPXM1, Hsap\CPXM2, Hsap\CPM, Hsap\CPZ, Hsap\CPE, Hsap\AEBP1, Hsap\CPN1, Hsap\CPD" embryonic stage "viable,electrophoretic variant,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,poor,body color defective,cold stress response defective,memory defective,fertile,partially lethal - majority die" "wing,wing blade,wing vein,wing vein L3,wing vein L4,wing vein L5,anterior crossvein,posterior crossvein,microchaeta,wing vein L1,wing vein L2" FBgn0044419 Pmi Pmi http://flybase.org/reports/FBgn0044419 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype mitochondrial ATP synthesis coupled electron transport ; GO:0042775 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype inner mitochondrial membrane organization ; GO:0007007 | inferred from mutant phenotype integral component of mitochondrial inner membrane ; GO:0031305 | inferred from electronic annotation with InterPro:IPR026120 mitochondrial inner membrane ; GO:0005743 | inferred from direct assay "PMI, CG32912, CG33718, CG5523, Pmi" IPR026120:Transmembrane protein 11 CG33718 11-Aug-17 DroID_v2017_08 Drer\tmem11 - - Xtro\tmem11 Mmus\Tmem11 Hsap\TMEM11 FBgn0005418 l(1)adl7 lethal (1) adl7 http://flybase.org/reports/FBgn0005418 - gene - - - "l(1)adl-7, l(1)adl7" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,female sterile" FBgn0259608 B0799 - http://flybase.org/reports/FBgn0259608 gene - - - B0799 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "tarsal segment,proboscis" FBgn0000659 fkh fork head http://flybase.org/reports/FBgn0000659 FBgn0015292 protein_coding_gene "protein domain specific binding ; GO:0019904 | inferred from electronic annotation with InterPro:IPR013638 transcription factor binding ; GO:0008134 | inferred from electronic annotation with InterPro:IPR013638 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" negative regulation of programmed cell death ; GO:0043069 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay endoderm formation ; GO:0001706 | traceable author statement salivary gland morphogenesis ; GO:0007435 | traceable author statement ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from direct assay negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | traceable author statement salivary gland development ; GO:0007431 | non-traceable author statement salivary gland development ; GO:0007431 | inferred from mutant phenotype negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype ectodermal digestive tract development ; GO:0007439 | traceable author statement neuroendocrine cell differentiation ; GO:0061101 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | traceable author statement DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "Fkh, FKH, Dmfkh, Sebp2, CG10002, fkh, dFoxA" "IPR018122:Fork head domain conserved site1, IPR018533:Forkhead box protein, C-terminal, IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR013638:Fork-head N-terminal, IPR030456:Fork head domain conserved site 2" CG10002 11-Aug-17 DroID_v2017_08 "Drer\foxa1, Drer\foxd1, Drer\foxc1b, Drer\foxa2, Drer\zgc:162612, Drer\foxd5, Drer\si:rp71-45k5.2, Drer\foxc1a, Drer\foxd3, Drer\foxe1, Drer\foxd2, Drer\foxl1, Drer\foxa, Drer\zgc:113424, Drer\foxe3, Drer\foxa3" - "Cele\unc-130, Cele\fkh-6, Cele\pha-4" "Xtro\foxi4.2, Xtro\foxc2, Xtro\foxa2, Xtro\foxd2, Xtro\foxa1, Xtro\foxl1, Xtro\foxc1, Xtro\foxd3, Xtro\foxe1, Xtro\foxa4, Xtro\foxe3, Xtro\foxd1, Xtro\foxd4l1.1" "Mmus\Foxc2, Mmus\Foxs1, Mmus\Foxa1, Mmus\Foxl1, Mmus\Foxa2, Mmus\Foxd3, Mmus\Foxd4, Mmus\Foxd1, Mmus\Foxa3, Mmus\Foxc1, Mmus\Foxe1, Mmus\Foxd2" "Hsap\FOXI3, Hsap\FOXC2, Hsap\FOXD4, Hsap\FOXD4L6, Hsap\FOXD4L4, Hsap\FOXA1, Hsap\FOXS1, Hsap\FOXD4L3, Hsap\FOXE1, Hsap\FOXL1, Hsap\FOXD4L5, Hsap\FOXD2, Hsap\FOXC1, Hsap\FOXA3, Hsap\FOXD1, Hsap\FOXD3, Hsap\FOXA2, Hsap\FOXD4L1" " embryonic stage | stage 4 , embryonic stage | stage 15 , embryonic stage | stage 13 , embryonic stage | stage 10 , embryonic stage | stage 5 " " organism | 0-20% egg length

,

terminal , hindgut

, Malpighian tubule

,

0-10% egg length , inclusive hindgut primordium

, organism | 90-100% egg length

" " embryonic stage | early , embryonic stage | stage 5 , larval stage | third instar , embryonic stage | stage >11 , embryonic stage | stage 9 " "

posterior , organism | 90-100% egg length

, larval salivary gland

, embryonic central nervous system | presumptive

, organism | 0-20% egg length

, anterior embryonic/larval midgut

, stomodeum

, embryonic/larval salivary gland

, yolk

" "increased cell size,conditional,small body,decreased cell size,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,decreased cell death,lethal,increased cell death,neuroanatomy defective,viable,visible" "cephalopharyngeal skeleton,anal plate,Malpighian tubule primordium,embryonic head,embryo,posterior,embryonic/larval salivary gland,salivary gland,embryonic/larval hindgut,Malpighian tubule,embryonic/larval proventriculus,embryonic/larval esophagus,embryonic brain,embryonic central brain glial cell,embryonic brain & ganglion mother cell,anterior midgut primordium,external sensory organ,ectopic,embryonic/larval foregut,anterior embryonic/larval midgut,labial disc,stomatogastric nervous system,longitudinal visceral muscle primordium,adult salivary gland primordium,embryonic stomatogastric nervous system,embryonic visceral muscle,embryonic hindgut,embryonic central brain,pars intercerebralis,salivary gland common duct primordium,hemocyte,macrophage,visceral mesoderm derivative,somatic mesoderm,mesothoracic tergum" FBgn0051999 CG31999 - http://flybase.org/reports/FBgn0051999 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" - - "CG10323, CT7856, CT31491, CG11288, CG31999" "IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR009030:Growth factor receptor cysteine-rich domain, IPR018097:EGF-like calcium-binding, conserved site, IPR026823:Complement Clr-like EGF domain" CG31999 11-Aug-17 DroID_v2017_08 "Drer\sned1, Drer\scube3, Drer\svep1, Drer\efemp2a, Drer\si:ch73-173h19.3, Drer\dlb, Drer\crb2a, Drer\col28a1a, Drer\megf6b, Drer\fbln1, Drer\dpy19l1l, Drer\fbln7, Drer\matn3a, Drer\scube1, Drer\crb2b, Drer\jag1b, Drer\adgrf6, Drer\efemp2b, Drer\jag2a, Drer\LOC562634, Drer\adgrl4, Drer\col28a1a, Drer\efemp1, Drer\fbln2, Drer\ltbp3, Drer\LOC100332841, Drer\si:ch211-221n20.8, Drer\jag2b, Drer\jag1a, Drer\fbln5, Drer\zgc:158328, Drer\LOC100535882" - Cele\fbl-1 "Xtro\fbln1, Xtro\hgfac, Xtro\efemp1, Xtro\efemp2, Xtro\ltbp3, Xtro\ltbp4, Xtro\svep1, Xtro\jag1, Xtro\fbln5, Xtro\nell1, Xtro\f12, Xtro\fbln2, Xtro\crb2, Xtro\col14a1, Xtro\notch1, Xtro\matn4, Xtro\fbn1" "Mmus\Vwde, Mmus\Hgfac, Mmus\Fbn1, Mmus\Svep1, Mmus\Ltbp4, Mmus\Ltbp1, Mmus\Cfc1, Mmus\Sned1, Mmus\Dll3, Mmus\Fbln5, Mmus\Dlk1, Mmus\Egfl7, Mmus\Habp2, Mmus\Vwa2, Mmus\Vwa1, Mmus\F12, Mmus\Dlk2, Mmus\Efemp2, Mmus\Hmcn2, Mmus\Fbln1, Mmus\Matn3, Mmus\Dll4, Mmus\Jag1, Mmus\Scube2, Mmus\Fbln7, Mmus\Vwce, Mmus\Jag2, Mmus\Col28a1, Mmus\Crb2, Mmus\Scube3, Mmus\Tdgf1, Mmus\Ltbp3, Mmus\Col22a1, Mmus\Efemp1, Mmus\Fbln2" "Hsap\LTBP1, Hsap\JAG2, Hsap\DLL3, Hsap\LTBP3, Hsap\FBLN1, Hsap\HABP2, Hsap\DLL4, Hsap\JAG1, Hsap\DLK1, Hsap\EGFL7, Hsap\SCUBE3, Hsap\NOTCH2NL, Hsap\EFEMP2, Hsap\SVEP1, Hsap\FBLN5, Hsap\EYS, Hsap\VWCE, Hsap\SNED1, Hsap\VWA1, Hsap\EFEMP1, Hsap\COL14A1, Hsap\F12, Hsap\DLK2, Hsap\TDGF1, Hsap\SCUBE2, Hsap\FBN3, Hsap\CFC1, Hsap\FBLN2, Hsap\CRB2, Hsap\CFC1B, Hsap\MATN3, Hsap\COL22A1, Hsap\HGFAC, Hsap\COL6A3, Hsap\FBLN7, Hsap\LOC100996717" "viable,visible" trichogen cell DRSC17131 K -0.240991472 0.105017927 0.23646923 0.429536228 2.231312979 0.904741531 FBgn0010803 TrpRS Tryptophanyl-tRNA synthetase http://flybase.org/reports/FBgn0010803 FBgn0037673 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002305, InterPro:IPR002306 tryptophan-tRNA ligase activity ; GO:0004830 | traceable author statement tryptophan-tRNA ligase activity ; GO:0004830 | inferred from direct assay" neurogenesis ; GO:0022008 | inferred from mutant phenotype tryptophanyl-tRNA aminoacylation ; GO:0006436 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype tryptophanyl-tRNA aminoacylation ; GO:0006436 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002306 cytoplasm ; GO:0005737 | traceable author statement "CG9735, WRS-85D, TrpRS, 85D-WRS, l(3)3559, l(3)03560, l(3)03559, WRS, wars, Aats-trp" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002305:Aminoacyl-tRNA synthetase, class Ic, IPR002306:Tryptophan-tRNA ligase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG9735 11-Aug-17 DroID_v2017_08 Drer\wars Scer\WRS1 Cele\wars-1 Xtro\wars Mmus\Wars Hsap\WARS " embryonic stage , embryonic stage -- adult stage " embryonic/larval salivary gland

embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "lethal,recessive,neuroanatomy defective,somatic clone,viable,decreased cell size,cell autonomous" "egg,germline clone,adult antennal lobe projection neuron,somatic clone,gamma Kenyon cell,embryonic/larval neuroblast,ganglion mother cell,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0086784 stmA stambha A http://flybase.org/reports/FBgn0086784 protein_coding_gene - chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from direct assay regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype synapse ; GO:0045202 | inferred from direct assay "stmA, cmp44E, rbo, stm-A, CG8739, stambhA" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG8739 11-Aug-17 DroID_v2017_08 "Drer\efr3a, Drer\efr3ba, Drer\efr3bb" Scer\EFR3 Cele\C32D5.3 "Xtro\efr3a, Xtro\efr3b" "Mmus\Efr3b, Mmus\Efr3a" "Hsap\EFR3A, Hsap\EFR3B" " embryonic stage , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage&&adult stage , adult stage && oogenesis stage | stage >=S9 , adult stage && oogenesis stage | stage S1-5 " " embryonic brain

, germarium

, embryonic central nervous system

,

ubiquitous , nurse cell

, follicle cell

" FBgn0030773 CG9676 - http://flybase.org/reports/FBgn0030773 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP99, CG9676" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG9676 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-16l2.17, Drer\zgc:163079, Drer\LOC100004427, Drer\si:dkeyp-93a5.3, Drer\zgc:165423, Drer\ovch1, Drer\gzm3, Drer\zgc:92313, Drer\gzmk, Drer\gzma, Drer\si:dkey-21e2.16, Drer\cfd, Drer\si:ch211-165b19.9, Drer\LOC558805, Drer\si:ch211-165b19.5, Drer\si:dkey-21e2.3, Drer\si:ch211-165b19.8" - "Cele\try-5, Cele\try-6, Cele\try-1" - "Mmus\Klk1b4, Mmus\Klk1b8, Mmus\Klk15, Mmus\Klk9, Mmus\Prss48, Mmus\Prss55" "Hsap\KLK15, Hsap\KLK9" "viable,visible" trichogen cell FBgn0031732 CG11149 - http://flybase.org/reports/FBgn0031732 protein_coding_gene - - - "CG11149, dibeta3GnT4" - CG11149 11-Aug-17 DroID_v2017_08 "Drer\gxylt1a, Drer\large, Drer\xxylt1, Drer\gxylt1b, Drer\b4gat1, Drer\gxylt2" - "Cele\bgnt-1.7, Cele\bgnt-1.3, Cele\bgnt-1.4, Cele\bgnt-1.5, Cele\bgnt-1.1, Cele\bgnt-1.8, Cele\bgnt-1.2, Cele\bgnt-1.6" "Xtro\b4gat1, Xtro\gyltl1b, Xtro\xxylt1, Xtro\large, Xtro\gxylt1, Xtro\gxylt2" "Mmus\Gxylt1, Mmus\Gxylt2, Mmus\Large2, Mmus\B4gat1, Mmus\Large1, Mmus\Xxylt1" "Hsap\B4GAT1, Hsap\LARGE1, Hsap\LARGE2, Hsap\GXYLT2, Hsap\GXYLT1, Hsap\XXYLT1" viable FBgn0028375 heix heixuedian http://flybase.org/reports/FBgn0028375 protein_coding_gene prenyltransferase activity ; GO:0004659 | inferred from biological aspect of ancestor with PANTHER:PTN000358054 "regulation of Toll signaling pathway ; GO:0008592 | inferred from mutant phenotype menaquinone biosynthetic process ; GO:0009234 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype regulation of Ras protein signal transduction ; GO:0046578 | inferred from mutant phenotype ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate ; GO:0032194 | inferred from biological aspect of ancestor with PANTHER:PTN000358054 negative regulation of hemocyte proliferation ; GO:0035207 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype regulation of MAPK cascade ; GO:0043408 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype vitamin K biosynthetic process ; GO:0042371 | inferred from biological aspect of ancestor with PANTHER:PTN000358054" mitochondrion ; GO:0005739 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with UniProtKB:Q9Y5Z9 integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN001016945 endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "l(2)35Fc, ipa-6d, BG:DS02740.7, 124/1, l(2)k12401, CG5876, heix" "IPR000537:UbiA prenyltransferase family, IPR026046:UbiA prenyltransferase domain containing protein 1" CG5876 11-Aug-17 DroID_v2017_08 Drer\ubiad1 - "Cele\srz-56, Cele\srz-44, Cele\srz-83, Cele\srz-20, Cele\srz-70, Cele\srz-32, Cele\srz-16, Cele\srz-78, Cele\F40G9.15, Cele\srz-71, Cele\srz-54, Cele\srz-38, Cele\srz-79, Cele\srz-64, Cele\srz-3, Cele\srz-23, Cele\srz-74, Cele\srz-31, Cele\srz-15, Cele\srz-91, Cele\srz-37, Cele\srz-25, Cele\srz-58" Xtro\ubiad1 Mmus\Ubiad1 Hsap\UBIAD1 "lethal,recessive,visible,melanotic mass phenotype,viable" "imaginal disc,wing vein,melanotic mass,hemocyte,wing,trichogen cell,mesothoracic tergum" FBgn0053852 His1:CG33852 His1:CG33852 http://flybase.org/reports/FBgn0053852 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33852, His1:CG33852" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33852 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-261m9.12, Drer\si:ch211-113a14.24, Drer\h1f0, Drer\si:ch1073-159d7.7, Drer\zgc:153405, Drer\zgc:110425, Drer\zgc:110216, Drer\h1m, Drer\zgc:163061, Drer\si:dkey-108k21.10, Drer\si:dkey-108k21.14, Drer\si:dkey-108k21.21, Drer\histh1l, Drer\si:ch73-36p18.1, Drer\h1fx" Scer\HHO1 "Cele\hil-1, Cele\his-24, Cele\hil-5, Cele\hil-2, Cele\hil-6, Cele\hil-4, Cele\hil-3" - "Mmus\Hist1h1b, Mmus\Hist1h1t, Mmus\Hist1h1e, Mmus\H1foo, Mmus\Hist1h1a, Mmus\H1fx, Mmus\H1fnt, Mmus\Hist1h1c, Mmus\Hils1, Mmus\Hist1h1d" "Hsap\HIST1H1T, Hsap\HIST1H1A, Hsap\H1FNT, Hsap\H1FX, Hsap\HIST1H1D, Hsap\HIST1H1B, Hsap\H1FOO, Hsap\HIST1H1E, Hsap\HIST1H1C, Hsap\H1F0" FBgn0033812 Pex13 Peroxin 13 http://flybase.org/reports/FBgn0033812 protein_coding_gene - "protein import into peroxisome matrix, docking ; GO:0016560 | inferred from electronic annotation with InterPro:IPR007223 spermatocyte division ; GO:0048137 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007223 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8855 "CG4663, Pex13, DmelPex13, pex13, PEX13" "IPR001452:SH3 domain, IPR007223:Peroxin 13, N-terminal" CG4663 11-Aug-17 DroID_v2017_08 "Drer\arhgef9b, Drer\spata13, Drer\arhgef4, Drer\prex1, Drer\arhgef9a, Drer\vav2, Drer\pex13, Drer\vav3b" "Scer\PEX13, Scer\CDC24" "Cele\Y37A1B.17, Cele\vav-1, Cele\prx-13, Cele\uig-1, Cele\tiam-1" Xtro\pex13 "Mmus\Prex1, Mmus\Arhgef4, Mmus\Plekhg2, Mmus\Vav3, Mmus\Arhgef9, Mmus\Plekhg1, Mmus\Plekhg3, Mmus\Vav1, Mmus\Spata13, Mmus\Vav2, Mmus\Pex13" "Hsap\ARHGEF4, Hsap\ARHGEF9, Hsap\PLEKHG3, Hsap\VAV1, Hsap\SPATA13, Hsap\PEX13, Hsap\VAV3, Hsap\PLEKHG2, Hsap\PREX1, Hsap\PLEKHG1, Hsap\VAV2" "viable,cytokinesis defective,meiotic cell cycle defective" "spermatid,testis" FBgn0086693 iav inactive http://flybase.org/reports/FBgn0086693 protein_coding_gene calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000832860 cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with pyx calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 thermosensory behavior ; GO:0040040 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity sensory perception of sound ; GO:0007605 | inferred from mutant phenotype neuromuscular process controlling posture ; GO:0050884 | inferred from mutant phenotype thermotaxis ; GO:0043052 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype response to auditory stimulus ; GO:0010996 | inferred from direct assay cation transport ; GO:0006812 | inferred from sequence or structural similarity with pyx behavioral response to cocaine ; GO:0048148 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred from sequence or structural similarity response to heat ; GO:0009408 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype negative gravitaxis ; GO:0048060 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000061616 cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with pyx "iav, TRPV, CG4536, CT14708, hypoB, IAV, DmIav, osm-9, Iav" "IPR005821:Ion transport domain, IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR024862:Transient receptor potential cation channel subfamily V" CG4536 11-Aug-17 DroID_v2017_08 "Drer\trpv1, Drer\trpv6, Drer\trpv4" Scer\YVC1 "Cele\ocr-2, Cele\ocr-4, Cele\osm-9" "Xtro\trpv3, Xtro\trpv2, Xtro\trpv1, Xtro\trpv4" "Mmus\Trpv5, Mmus\Trpv2, Mmus\Trpv1, Mmus\Trpv6, Mmus\Trpv4, Mmus\Trpv3" "Hsap\TRPV5, Hsap\TRPV2, Hsap\TRPV4, Hsap\TRPV3, Hsap\TRPV6, Hsap\TRPV1" FBgn0261387 CG17528 - http://flybase.org/reports/FBgn0261387 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity calmodulin binding ; GO:0005516 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 calcium-dependent protein serine/threonine kinase activity ; GO:0009931 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with UniProtKB:P0C1X8 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 protein autophosphorylation ; GO:0046777 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:P0C1X8 protein phosphorylation ; GO:0006468 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 "PK1, Pk1, CAMK-like, CG40283, CG17528" "IPR000719:Protein kinase domain, IPR003533:Doublecortin domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG17528 11-Aug-17 DroID_v2017_08 "Drer\dclk3, Drer\dapk1, Drer\dapk2b, Drer\triob, Drer\dcdc2b, Drer\mylk4b, Drer\spegb, Drer\camk1a, Drer\zgc:153952, Drer\camk1da, Drer\dclk1a, Drer\mylk4a, Drer\pnck, Drer\dapk3, Drer\rp1l1a, Drer\trioa, Drer\dclk1b, Drer\dclk2b, Drer\camk1gb, Drer\stk17a, Drer\camk1b, Drer\ttnb, Drer\rp1l1b, Drer\camk4, Drer\uhmk1, Drer\mylk3, Drer\rp1, Drer\si:dkey-240h12.4, Drer\camk1ga, Drer\si:ch211-27e6.1, Drer\stk33, Drer\camk1db, Drer\si:ch73-60h1.1, Drer\stk17b, Drer\camkvl, Drer\capsla, Drer\dapk2a, Drer\camkva, Drer\camkvb, Drer\pskh1, Drer\capslb, Drer\dclk2a" "Scer\IKS1, Scer\CMK1, Scer\RCK2, Scer\RCK1, Scer\CMK2, Scer\TDA1, Scer\MEK1, Scer\DUN1" "Cele\F32D8.1, Cele\zyg-8" "Xtro\kalrn, Xtro\camk1, Xtro\dclk2, Xtro\camkv, Xtro\dcdc2, Xtro\stk17a, Xtro\pskh2, Xtro\camk4, Xtro\pskh1, Xtro\pnck, Xtro\camk1d, Xtro\camk1g, Xtro\mylk3, Xtro\capsl, Xtro\caps, Xtro\dcx, Xtro\dapk2, Xtro\mylk4, Xtro\dapk1, Xtro\dclk3, Xtro\trio, Xtro\dapk3, Xtro\stk33" "Mmus\Camkv, Mmus\Rp1l1, Mmus\Mylk3, Mmus\Pnck, Mmus\Capsl, Mmus\Dcdc2c, Mmus\Dapk2, Mmus\Speg, Mmus\Mylk2, Mmus\Mylk4, Mmus\Pskh1, Mmus\Obscn, Mmus\Camk1g, Mmus\Dclk3, Mmus\Camk1d, Mmus\Stk33, Mmus\Stk17b, Mmus\Dcdc2b, Mmus\Trio, Mmus\Dcx, Mmus\Uhmk1, Mmus\Caps2, Mmus\Dclk1, Mmus\Dclk2, Mmus\Dapk3, Mmus\Camk1, Mmus\Dcdc2a, Mmus\Dapk1, Mmus\Rp1, Mmus\Camk4" "Hsap\MYLK4, Hsap\TRIO, Hsap\DCDC2, Hsap\CAPS, Hsap\UHMK1, Hsap\DAPK3, Hsap\CAPS2, Hsap\MYLK2, Hsap\DAPK2, Hsap\RP1L1, Hsap\CAMK1, Hsap\CAMK1G, Hsap\CAPSL, Hsap\CAMKV, Hsap\DCDC2C, Hsap\STK17A, Hsap\MYLK3, Hsap\DCX, Hsap\DCDC2B, Hsap\STK17B, Hsap\RP1, Hsap\DCLK2, Hsap\DCLK1, Hsap\PNCK, Hsap\CAMK1D, Hsap\DAPK1, Hsap\DCLK3, Hsap\PSKH2, Hsap\PSKH1, Hsap\OBSCN, Hsap\SPEG, Hsap\CAMK4, Hsap\STK33" DRSC07761 K 1.452913501 0.131312635 0.282892923 0.325500783 0.500757903 1.656925502 FBgn0033215 CG1942 - http://flybase.org/reports/FBgn0033215 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR007130" mesoderm development ; GO:0007498 | non-traceable author statement - "CG1942, DGAT2" IPR007130:Diacylglycerol acyltransferase CG1942 11-Aug-17 DroID_v2017_08 "Drer\mogat3a, Drer\mogat2, Drer\dgat2, Drer\mogat3b" Scer\DGA1 "Cele\dgtr-1, Cele\dgat-2, Cele\K07B1.4, Cele\Y53G8B.2" "Xtro\dgat2l6, Xtro\awat1, Xtro\mogat3, Xtro\mogat1, Xtro\mogat2.1, Xtro\dgat2" "Mmus\Awat1, Mmus\Mogat2, Mmus\Dgat2, Mmus\Mogat1, Mmus\Dgat2l6, Mmus\Awat2" "Hsap\DGAT2, Hsap\AWAT1, Hsap\MOGAT3, Hsap\AWAT2, Hsap\MOGAT2, Hsap\DGAT2L6, Hsap\MOGAT1" "viable,fertile" FBgn0085387 shakB shaking B http://flybase.org/reports/FBgn0085387 protein_coding_gene gap junction channel activity ; GO:0005243 | inferred from mutant phenotype photoreceptor activity ; GO:0009881 | inferred from mutant phenotype transmembrane transport ; GO:0055085 | inferred from mutant phenotype intercellular transport ; GO:0010496 | inferred from sequence or structural similarity with Inx3 jump response ; GO:0007630 | inferred from mutant phenotype gap junction assembly ; GO:0016264 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype regulation of membrane depolarization ; GO:0003254 | inferred from mutant phenotype cell communication by electrical coupling ; GO:0010644 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay gap junction ; GO:0005921 | inferred from mutant phenotype gap junction ; GO:0005921 | inferred from direct assay "CG34358, shakB, shB, shak-B, Shak B, pass, Shak-B, pas, Pas, ShakB, shkB, R-9-29, l(1)R-9-29, l(1)W3, R9-29, W3, E81, 6, 3, 2, nj156, nj-156, l(1)W3b, l(1)TH73, l(1)R-10-7, l(1)R-10-3, l(1)R-10-14, l(1)LB21, l(1)19Eb, CG15451, CG1321, CG32508, CG12678, FBpp0111481, inx8, lincRNA.1031" IPR000990:Innexin CG34358 11-Aug-17 DroID_v2017_08 "Drer\panx1b, Drer\panx3" - "Cele\che-7, Cele\inx-9, Cele\inx-1, Cele\inx-21, Cele\inx-14, Cele\inx-19, Cele\inx-7, Cele\unc-9, Cele\inx-10, Cele\inx-11, Cele\inx-5, Cele\inx-13, Cele\inx-18, Cele\inx-12, Cele\unc-7, Cele\inx-22, Cele\eat-5, Cele\inx-20, Cele\inx-2, Cele\inx-8, Cele\inx-17, Cele\inx-15, Cele\inx-6, Cele\inx-3, Cele\inx-16" - - - " adult stage , pupal stage | >75hr " " mesothoracic neuromere

, giant fibers

" FBgn0029174 FKBP59 FK506-binding protein FKBP59 http://flybase.org/reports/FBgn0029174 protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 protein binding ; GO:0005515 | inferred from physical interaction with inaD inferred from physical interaction with trpl FK506 binding ; GO:0005528 | inferred from sequence or structural similarity with HGNC:3720 FK506 binding ; GO:0005528 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 peripheral nervous system development ; GO:0007422 | traceable author statement detection of light stimulus involved in visual perception ; GO:0050908 | inferred from physical interaction with inaD inferred from physical interaction with trpl regulation of calcium ion transport ; GO:0051924 | inferred from direct assay inaD signaling complex ; GO:0016027 | inferred from physical interaction with inaD cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 "CG4535, dFKBP59, l(2)k00424, FKBP59-bp1, l(2)k09010, anon-WO0118547.161, FKBP59, fkbp59" "IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR001440:Tetratricopeptide repeat 1" CG4535 11-Aug-17 DroID_v2017_08 "Drer\fkbp1aa, Drer\fkbp6, Drer\fkbp1ab, Drer\fkbp1b, Drer\fkbp4, Drer\fkbp16, Drer\fkbp8, Drer\fkbp5" Scer\FPR1 "Cele\fkb-6, Cele\fkb-8, Cele\fkb-2" "Xtro\fkbp6, Xtro\fkbp4, Xtro\fkbp8" "Mmus\Fkbp5, Mmus\Fkbp8, Mmus\Fkbp4, Mmus\Fkbp6, Mmus\Fkbp1a, Mmus\Fkbp1b" "Hsap\FKBP1B, Hsap\FKBP4, Hsap\FKBP8, Hsap\FKBP6, Hsap\FKBP1A, Hsap\FKBP5" " embryonic stage | stage >=13 , embryonic stage -- adult stage , embryonic stage | stage >=16 " " embryonic/larval garland cell

, embryonic/larval oenocyte

, lymph gland

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,fertile,partially lethal - majority die" "crystal cell,plasmatocyte,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,fascicle" FBgn0004360 Wnt2 Wnt oncogene analog 2 http://flybase.org/reports/FBgn0004360 - protein_coding_gene "receptor binding ; GO:0005102 | inferred from sequence or structural similarity with wg frizzled binding ; GO:0005109 | inferred from physical interaction with fz, fz2, fz3" axon extension ; GO:0048675 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 Wnt signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with wg muscle organ development ; GO:0007517 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 open tracheal system development ; GO:0007424 | inferred from genetic interaction with wg extracellular region ; GO:0005576 | inferred from sequence or structural similarity with wg extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 "Wnt-2, DWnt2, DWnt-2, dWnt2, Wnt, Dwnt-2, D-wnt-2, Dm-2, CG1916, Wnt2, wnt2, Dm DWnt2, Dwnt2, wnt-2" "IPR018161:Wnt protein, conserved site, IPR005817:Wnt" CG1916 11-Aug-17 DroID_v2017_08 "Drer\wnt7ba, Drer\wnt6b, Drer\wnt2bb, Drer\wnt8b, Drer\wnt6a, Drer\wnt11r, Drer\wnt3, Drer\wnt1, Drer\wnt10b, Drer\wnt11, Drer\wnt2ba, Drer\LOC568110, Drer\wnt2, Drer\wnt9b, Drer\wnt8a, Drer\wnt5a, Drer\wnt3a, Drer\wnt9a, Drer\wnt7bb, Drer\wnt10a, Drer\wnt7aa, Drer\wnt16, Drer\wnt5b, Drer\wnt4a, Drer\wnt4b" - "Cele\egl-20, Cele\cwn-1, Cele\cwn-2, Cele\mom-2" "Xtro\wnt9b.2, Xtro\wnt16, Xtro\wnt7b, Xtro\wnt3a, Xtro\wnt10b, Xtro\wnt8a, Xtro\wnt8b, Xtro\wnt7a, Xtro\wnt11r, Xtro\wnt5b, Xtro\wnt2b, Xtro\wnt9b, Xtro\wnt11, Xtro\wnt7c, Xtro\wnt1, Xtro\wnt4" "Mmus\Wnt1, Mmus\Wnt2b, Mmus\Wnt2, Mmus\Wnt5a, Mmus\Wnt3, Mmus\Wnt8a, Mmus\Wnt10a, Mmus\Wnt10b, Mmus\Wnt4, Mmus\Wnt6, Mmus\Wnt7b, Mmus\Wnt3a, Mmus\Wnt11, Mmus\Wnt16, Mmus\Wnt7a, Mmus\Wnt9b, Mmus\Wnt5b, Mmus\Wnt9a, Mmus\Wnt8b" "Hsap\WNT9A, Hsap\WNT8A, Hsap\WNT6, Hsap\WNT11, Hsap\WNT2B, Hsap\WNT10A, Hsap\WNT5A, Hsap\WNT10B, Hsap\WNT9B, Hsap\WNT8B, Hsap\WNT3, Hsap\WNT16, Hsap\WNT4, Hsap\WNT1, Hsap\WNT7B, Hsap\WNT7A, Hsap\WNT2, Hsap\WNT3A, Hsap\WNT5B" " embryonic stage | stage 5 , embryonic stage | stage 10-11 , pupal stage | 24 hr , embryonic stage | stage >=14 , embryonic stage | stage 16 , embryonic stage | stage >=13 , wandering third instar larval stage , embryonic stage | stage 7 , embryonic stage | stage 15 , embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | stage 13 , embryonic stage--pupal stage " " organism | 10-70% egg length

, thoracic segment &&of embryo

, seminal vesicle | restricted

, gonad | posterior

, abdominal segment 1--8 | restricted

, organism | anterior

, male genital disc primordium

, proctodeum

, gonad

, labial segment

, maxillary segment

, labrum

, organism | posterior

" "male sterile,recessive,viable,visible,flightless,heat sensitive,reduced,neuroanatomy defective,dominant,male semi-sterile,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "testis pigment cell,testis sheath muscle,wing,testis sheath,testis,muscle of third axillary 54,heat sensitive,basalar muscle 52,direct flight muscle,axon & dorsal cluster neuron,ectopic,ovary,somatic clone,direct flight muscle 49,direct flight muscle 50,muscle of first axillary 53,dorsal trunk primordium,embryonic/larval tracheal system" FBgn0000115 Arl1 ADP ribosylation factor-like 1 http://flybase.org/reports/FBgn0000115 "FBgn0064936, FBgn0016902" protein_coding_gene "GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with HGNC:692 protein domain specific binding ; GO:0019904 | inferred from physical interaction with Golgin245, GCC88, GCC185, cbs protein binding ; GO:0005515 | inferred from physical interaction with Sec71 GTP binding ; GO:0005525 | inferred from direct assay" small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 neurotransmitter secretion ; GO:0007269 | traceable author statement regulation of ER to Golgi vesicle-mediated transport ; GO:0060628 | inferred from mutant phenotype endoplasmic reticulum membrane organization ; GO:0090158 | inferred from mutant phenotype protein localization to Golgi apparatus ; GO:0034067 | inferred from mutant phenotype regulation of protein exit from endoplasmic reticulum ; GO:0070861 | inferred from mutant phenotype endosomal transport ; GO:0016197 | traceable author statement synaptic vesicle endocytosis ; GO:0048488 | traceable author statement regulation of cell migration ; GO:0030334 | inferred from mutant phenotype protein targeting to Golgi ; GO:0000042 | inferred from direct assay inferred from mutant phenotype secretory granule organization ; GO:0033363 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype salivary gland development ; GO:0007431 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype trans-Golgi network ; GO:0005802 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "arl, arf[72A], CG6025, Arl1, Arf, l(3)72Ae, dARL1p, BcDNA:GM20805, dArl1, arl1, Arf72A, 72CDd, l(3)72CDd, CG 6025, ARL1, ARL1_DROME, arf72A, P25160" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR024156:Small GTPase superfamily, ARF type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG6025 11-Aug-17 DroID_v2017_08 "Drer\arl1, Drer\arl16" Scer\ARL1 Cele\arl-1 "Xtro\arl16, Xtro\arl1" "Mmus\Arl1, Mmus\Arl16" "Hsap\ARL16, Hsap\ARL1" "lethal,recessive,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type" "syncytial blastoderm embryo,centrosome | embryonic stage 4,nucleus | embryonic stage 4,spindle,centrosome,nucleus,rough endoplasmic reticulum membrane | somatic clone,Golgi apparatus | somatic clone | supernumerary" DRSC09667 I 2.519406708 1.030597829 0.484817192 0.135591051 -0.42210832 0.307748674 FBgn0041761 dra drache http://flybase.org/reports/FBgn0041761 gene - - - dra - - 11-Aug-17 DroID_v2017_08 - - - - - - "melanotic mass phenotype,recessive,lethal,hyperplasia" "polytene chromosome,melanotic mass,embryonic/larval brain" FBgn0005654 Orc3 Origin recognition complex subunit 3 http://flybase.org/reports/FBgn0005654 "FBgn0002075, FBgn0004955, FBgn0023182" protein_coding_gene DNA replication origin binding ; GO:0003688 | inferred from biological aspect of ancestor with PANTHER:PTN000297471 DNA binding ; GO:0003677 | non-traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | non-traceable author statement olfactory learning ; GO:0008355 | traceable author statement sleep ; GO:0030431 | inferred from expression pattern border follicle cell migration ; GO:0007298 | inferred from mutant phenotype pre-replicative complex assembly involved in nuclear cell cycle DNA replication ; GO:0006267 | inferred from biological aspect of ancestor with PANTHER:PTN000297471 DNA replication initiation ; GO:0006270 | inferred from direct assay DNA replication ; GO:0006260 | non-traceable author statement learning or memory ; GO:0007611 | non-traceable author statement centrosome organization ; GO:0051297 | inferred from mutant phenotype learning ; GO:0007612 | non-traceable author statement "nuclear chromosome, telomeric region ; GO:0000784 | inferred from biological aspect of ancestor with PANTHER:PTN000297471 nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay nuclear pre-replicative complex ; GO:0005656 | inferred from biological aspect of ancestor with PANTHER:PTN000297471 DNA replication preinitiation complex ; GO:0031261 | inferred from biological aspect of ancestor with PANTHER:PTN000297471 mitotic spindle ; GO:0072686 | inferred from direct assay" "ORC3, ORC, Orc3, DmORC3, vr6, vr-6, l(2)49Fd, l(2)vr6, CG4088, lat, LAT, DmOrc3, orc3, latheo, Lat" "IPR020795:Origin recognition complex, subunit 3" CG4088 11-Aug-17 DroID_v2017_08 Drer\orc3 Scer\ORC3 "Cele\srh-122, Cele\srh-113, Cele\srh-120, Cele\srh-123, Cele\K12H6.7, Cele\srh-83" Xtro\orc3 Mmus\Orc3 Hsap\ORC3 " adult stage , embryonic stage&&larval stage " adult brain

" larval stage | third instar , adult stage " " bouton

, neuromuscular junction

, adult brain

" "lethal,memory defective,learning defective,recessive,viable,neurophysiology defective,neuroanatomy defective,locomotor behavior defective,behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,non-suppressor of variegation,dominant,suppressor of variegation,wild-type" "border follicle cell,somatic clone,adult mushroom body,axon terminus,bouton,imaginal disc,embryonic/larval central nervous system" FBgn0004849 Su(var)2-1 Suppressor of variegation 2-1 http://flybase.org/reports/FBgn0004849 "FBgn0003586, FBgn0003589, FBgn0003606, FBgn0003609, FBgn0003611, FBgn0003615, FBgn0003616, FBgn0003617" gene - - - "Suvar(2)1, Su(Var)2-1, Su(var)210, Su(var)2-101, Su(var)2, Su-var(2)1, Su(var), Su(var)216, Su(var)b[101], Suvar(2)1[o1], Su(var)2-1" - - 11-Aug-17 DroID_v2017_08 - - - - - - "suppressor of variegation,dominant,lethal,male,recessive,female,partially,viable,non-suppressor of variegation,fertile,female sterile" pigment cell FBgn0025680 cry cryptochrome http://flybase.org/reports/FBgn0025680 "FBgn0044674, FBgn0044686, FBgn0044708, FBgn0046448" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with tim flavin adenine dinucleotide binding ; GO:0050660 | inferred from mutant phenotype photoreceptor activity ; GO:0009881 | inferred from direct assay photoreceptor activity ; GO:0009881 | non-traceable author statement blue light photoreceptor activity ; GO:0009882 | inferred from mutant phenotype FAD binding ; GO:0071949 | inferred from direct assay photoreceptor activity ; GO:0009881 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P07663 flavin adenine dinucleotide binding ; GO:0050660 | inferred from direct assay DNA photolyase activity ; GO:0003913 | NOT inferred from mutant phenotype G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with HGNC:2384 inferred from sequence or structural similarity with HGNC:2385 "circadian rhythm ; GO:0007623 | inferred from genetic interaction with per inferred from genetic interaction with tim regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype regulation of circadian rhythm ; GO:0042752 | inferred from direct assay circadian rhythm ; GO:0007623 | inferred from physical interaction with tim entrainment of circadian clock ; GO:0009649 | inferred from direct assay blue light signaling pathway ; GO:0009785 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from mutant phenotype entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype magnetoreception ; GO:0050958 | inferred from mutant phenotype regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype response to magnetism ; GO:0071000 | inferred from mutant phenotype protein import into nucleus, translocation ; GO:0000060 | inferred from mutant phenotype detection of light stimulus involved in magnetoreception ; GO:0050980 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | traceable author statement circadian rhythm ; GO:0007623 | inferred from expression pattern response to blue light ; GO:0009637 | traceable author statement gravitaxis ; GO:0042332 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype UV-A, blue light phototransduction ; GO:0009588 | inferred from sequence or structural similarity with HGNC:2384 inferred from sequence or structural similarity with HGNC:2385 circadian rhythm ; GO:0007623 | non-traceable author statement response to light stimulus ; GO:0009416 | traceable author statement entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype inferred from genetic interaction with Rh5, Rh6 inferred from genetic interaction with Rh5, Rh6, norpA inferred from genetic interaction with Rh5, norpA inferred from genetic interaction with Rh6, norpA inferred from genetic interaction with norpA response to blue light ; GO:0009637 | non-traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nuclear envelope lumen ; GO:0005641 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with tim "cry, CRY, dCRY, Cry, dCry, DCry, dcry, DmCRY1, Dm-CRY1, cryb, anon-WO0172774.15, CG3772, anon-WO0140519.20, anon-WO0140519.19, anon-WO0140519.17, DmCRY, Dmcry, DmCry1, DmCry" "IPR002081:Cryptochrome/DNA photolyase class 1, IPR005101:Cryptochrome/DNA photolyase, FAD-binding domain, IPR006050:DNA photolyase, N-terminal, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG3772 11-Aug-17 DroID_v2017_08 "Drer\cry-dash, Drer\cry1bb, Drer\cry5, Drer\zgc:66475, Drer\cry1aa, Drer\cry1ba, Drer\si:ch1073-390k14.1, Drer\cry2, Drer\cry1ab, Drer\cry4" Scer\PHR1 - "Xtro\cry1, Xtro\cry4, Xtro\cry2" "Mmus\Cry2, Mmus\Cry1" "Hsap\CRY2, Hsap\CRY1" " adult stage , larval stage , pupal stage " " mouthpart

, leg

, pupal/adult digestive system | restricted

, neuron | subset

, adult head

, antenna

, adult central nervous system

, adult brain

" adult stage adult head

"locomotor rhythm defective,circadian behavior defective,viable,fertile,circadian rhythm defective,recessive,photoperiod response variant,gravitaxis defective,eclosion rhythm defective,behavior defective" "antenna,pacemaker neuron" DRSC16928 E 0.449375925 0.285041601 2.790656486 -0.035784889 -0.22056617 -0.384923258 FBgn0003994 vtw vertical wings http://flybase.org/reports/FBgn0003994 - gene - muscle organ development ; GO:0007517 | inferred from mutant phenotype striated muscle tissue development ; GO:0014706 | inferred from mutant phenotype - vtw - - 11-Aug-17 DroID_v2017_08 - - - - - - "flightless,viable,recessive,locomotor behavior defective,visible,reduced" "wing,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,myofibril,Z disc,tergosternal muscle 47a,tergosternal muscle 47b,tergosternal muscle 47c,dorsal medial muscle 45c,dorsal medial muscle 45d,dorsal medial muscle 45e,dorsal medial muscle 45f,coxal tergal remotor muscle 48a,coxal tergal remotor muscle 48b,lateral oblique dorsal muscle 46a,lateral oblique dorsal muscle 46b,thorax,adult thorax" FBgn0038984 AdipoR Adiponectin receptor http://flybase.org/reports/FBgn0038984 protein_coding_gene hormone binding ; GO:0042562 | inferred from biological aspect of ancestor with PANTHER:PTN001074076 protein-hormone receptor activity ; GO:0016500 | inferred from sequence or structural similarity with UniProtKB:Q96A54 fatty acid oxidation ; GO:0019395 | inferred from sequence or structural similarity with UniProtKB:Q96A54 hormone-mediated signaling pathway ; GO:0009755 | inferred from mutant phenotype hormone-mediated signaling pathway ; GO:0009755 | inferred from sequence or structural similarity with UniProtKB:Q96A54 triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype positive regulation of insulin secretion ; GO:0032024 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype glucose homeostasis ; GO:0042593 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004254 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001074076 "CG5315, AdipoR, dAdipoR" IPR004254:AdipoR/Haemolysin-III-related CG5315 11-Aug-17 DroID_v2017_08 "Drer\adipor1a, Drer\paqr3a, Drer\paqr5a, Drer\adipor2, Drer\paqr6, Drer\paqr4b, Drer\paqr7b, Drer\adipor1b, Drer\paqr8, Drer\paqr5b, Drer\paqr4a, Drer\paqr3b, Drer\paqr7a" "Scer\IZH2, Scer\IZH1, Scer\IZH4, Scer\IZH3" "Cele\paqr-1, Cele\paqr-2" "Xtro\paqr5, Xtro\paqr3, Xtro\paqr8, Xtro\adipor1, Xtro\paqr6, Xtro\paqr4" "Mmus\Adipor2, Mmus\LOC101055651, Mmus\Paqr5, Mmus\Paqr4, Mmus\Paqr6, Mmus\Paqr7, Mmus\Paqr8, Mmus\Paqr9, Mmus\Adipor1, Mmus\Paqr3" "Hsap\PAQR9, Hsap\ADIPOR1, Hsap\PAQR5, Hsap\PAQR4, Hsap\ADIPOR2, Hsap\PAQR6, Hsap\PAQR3, Hsap\MMD2, Hsap\PAQR8, Hsap\MMD, Hsap\PAQR7" "lethal - all die before end of pupal stage,some die during pupal stage,starvation stress response defective" FBgn0027583 CG7601 - http://flybase.org/reports/FBgn0027583 - protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - cellular_component ; GO:0005575 | no biological data available "BcDNA:GH06026, CG7601" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG7601 11-Aug-17 DroID_v2017_08 "Drer\hsd17b1, Drer\dhrs7ca, Drer\hsd11b1la, Drer\zmp:0000001048, Drer\dhrs7b, Drer\hsd11b1lb, Drer\zgc:109982, Drer\rdh8a, Drer\rdh8b, Drer\dhrs7cb, Drer\dhrs7" "Scer\LYS2, Scer\YMR226C" "Cele\T25G12.13, Cele\C33E10.10, Cele\T25G12.2, Cele\dhs-30" "Xtro\dhrs7c, Xtro\rdh8, Xtro\LOC100124812, Xtro\hsd11b1, Xtro\dhrs7b, Xtro\hsd17b7, Xtro\hsd11b1l.2, Xtro\hsd11b1l, Xtro\hsd17b1" "Mmus\Dhrs7b, Mmus\Hsd11b1, Mmus\Rdh8, Mmus\Dhrs7c, Mmus\Hsd17b1" "Hsap\RDH8, Hsap\HSD11B1, Hsap\DHRS7C, Hsap\HSD11B1L, Hsap\DHRS7B, Hsap\HSD17B1" viable FBgn0026319 Traf4 TNF-receptor-associated factor 4 http://flybase.org/reports/FBgn0026319 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001293, InterPro:IPR012227, InterPro:IPR013323 protein binding ; GO:0005515 | inferred from physical interaction with baz" "activation of NF-kappaB-inducing kinase activity ; GO:0007250 | inferred from electronic annotation with InterPro:IPR027138 phagocytosis ; GO:0006909 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from genetic interaction with bsk autophagic cell death ; GO:0048102 | inferred from expression pattern positive regulation of JNK cascade ; GO:0046330 | inferred from genetic interaction with bsk inferred from genetic interaction with hep inferred from genetic interaction with Tak1 adherens junction organization ; GO:0034332 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from mutant phenotype apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern ventral furrow formation ; GO:0007370 | inferred from mutant phenotype" apical cortex ; GO:0045179 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "dTRAF1, DTRAF, TRAF1, DTRAF1, dtraf1, dTRAF, dTraf1, TRAF, CG3048, traf4, Traf4, Traf1, traf1, dTraf4, traf-4, TRAF4, traf1/4, traf-1/4" "IPR001293:Zinc finger, TRAF-type, IPR002083:MATH/TRAF domain, IPR008974:TRAF-like, IPR012227:TNF receptor-associated factor TRAF, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027138:TNF receptor-associated factor 4" CG3048 11-Aug-17 DroID_v2017_08 "Drer\rnf151, Drer\pdzrn3b, Drer\traf1, Drer\rnf41l, Drer\traf4b, Drer\traf5, Drer\traf6, Drer\LOC100005446, Drer\traf4a, Drer\traf3, Drer\traf2a, Drer\pdzrn3a, Drer\traf2b, Drer\traf7" - "Cele\trf-1, Cele\Y110A7A.2" "Xtro\pdzrn3, Xtro\traf3, Xtro\traf6, Xtro\traf5, Xtro\traf2, Xtro\traf7, Xtro\traf4" "Mmus\Traf2, Mmus\Traf1, Mmus\Pdzrn4, Mmus\Traf3, Mmus\Traf6, Mmus\Pdzrn3, Mmus\Traf4, Mmus\Traf5, Mmus\Traf7" "Hsap\TRAF5, Hsap\TRAF3, Hsap\TRAF6, Hsap\PDZRN3, Hsap\TRAF4, Hsap\TRAF2, Hsap\TRAF1, Hsap\TRAF7, Hsap\PDZRN4" "lethal,size defective,lethal - all die before end of larval stage,some die during larval stage,increased cell death,viable,visible,immune response defective,lethal - all die before end of pupal stage,some die during pupal stage" "ventral furrow,embryonic/first instar larval cuticle,rescuable maternal effect,imaginal disc,eye disc,eye photoreceptor cell & axon,eye,ommatidium,eye photoreceptor cell,embryonic/larval salivary gland" FBgn0039136 CG5902 - http://flybase.org/reports/FBgn0039136 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.372, CG5902" "IPR002733:AMMECR1 domain, IPR023473:AMMECR1, IPR027485:AMMECR1, N-terminal" CG5902 11-Aug-17 DroID_v2017_08 Drer\ammecr1 Scer\YOR289W Cele\R166.3 Xtro\ammecr1 "Mmus\Ammecr1, Mmus\Ammecr1l" "Hsap\AMMECR1, Hsap\AMMECR1L" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0031799 Pez Pez http://flybase.org/reports/FBgn0031799 protein_coding_gene cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000242 negative regulation of hippo signaling ; GO:0035331 | inferred from genetic interaction with yki negative regulation of stem cell proliferation ; GO:2000647 | inferred from mutant phenotype cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 cell cortex ; GO:0005938 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "CG9493, PTPD1, Pez, dPez, PEZ" "IPR000242:PTP type protein phosphatase, IPR000299:FERM domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR016130:Protein-tyrosine phosphatase, active site, IPR018979:FERM, N-terminal, IPR018980:FERM, C-terminal PH-like domain, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029021:Protein-tyrosine phosphatase-like, IPR029071:Ubiquitin-related domain, IPR003595:Protein-tyrosine phosphatase, catalytic" CG9493 11-Aug-17 DroID_v2017_08 Drer\ptpn21 "Scer\PTP3, Scer\PTP2" "Cele\ptp-4, Cele\moa-1" "Xtro\ptpn21, Xtro\ptpn14" "Mmus\Ptpn14, Mmus\Ptpn21" "Hsap\PTPN14, Hsap\PTPN21" "viable,small body,developmental rate defective,semi-sterile,hyperplasia,visible,lethal - all die before end of pupal stage,some die during pupal stage" "adult midgut epithelium,eye,wing" FBgn0043456 CG4747 - http://flybase.org/reports/FBgn0043456 protein_coding_gene phosphogluconate dehydrogenase (decarboxylating) activity ; GO:0004616 | inferred from electronic annotation with InterPro:IPR006115 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR029154 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006115, InterPro:IPR008927, InterPro:IPR013328" polytene chromosome interband ; GO:0005705 | inferred from direct assay "BEST:LD22483, LD29743, Dm_AI388468, BEST:GH19401, BEST:LD29743, CG4747" "IPR000313:PWWP domain, IPR006115:6-phosphogluconate dehydrogenase, NADP-binding, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR013328:6-phosphogluconate dehydrogenase, domain 2, IPR016040:NAD(P)-binding domain, IPR029154:3-hydroxyisobutyrate dehydrogenase, NAD-binding domain" CG4747 11-Aug-17 DroID_v2017_08 "Drer\psip1, Drer\glyr1, Drer\hibadhb, Drer\hibadha, Drer\si:ch211-116m6.3, Drer\rogdi" - Cele\B0250.5 "Xtro\psip1, Xtro\glyr1, Xtro\hibadh, Xtro\hdgfrp2" "Mmus\Hibadh, Mmus\Hdgfrp2, Mmus\Psip1, Mmus\Glyr1" "Hsap\HDGFRP2, Hsap\GLYR1, Hsap\PSIP1, Hsap\HIBADH" visible "dorsocentral bristle,scutellar bristle,trichogen cell,tormogen cell" FBgn0035661 CG10477 - http://flybase.org/reports/FBgn0035661 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 endopeptidase activity ; GO:0004175 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP51, anon-WO0140519.232, CG10477" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG10477 11-Aug-17 DroID_v2017_08 "Drer\zgc:112368, Drer\zgc:112302, Drer\zgc:112285, Drer\zgc:163025, Drer\si:dkey-78l4.10, Drer\zgc:92041, Drer\zgc:92745, Drer\habp2, Drer\f9b, Drer\ela3l, Drer\masp2" - Cele\svh-1 - "Mmus\C1s1, Mmus\Ctrc, Mmus\Cela2a, Mmus\Ctsg, Mmus\Ctrl, Mmus\C1s2, Mmus\Cela1, Mmus\F9, Mmus\Ctrb1, Mmus\Cela3a, Mmus\Cela3b" "Hsap\CTSG, Hsap\C1S, Hsap\PROC" viable DRSC23989 K 0.299582339 -0.620406076 0.502234822 0.36693577 1.930415445 -0.659129085 FBgn0262124 uex unextended http://flybase.org/reports/FBgn0262124 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cellular ion homeostasis ; GO:0006873 | inferred from sequence or structural similarity with SGD:S000005421 cellular_component ; GO:0005575 | no biological data available "uex, CG40084, CR41594, CG42595, l(2)41Ad, 41Ad, l(2)EMS34-7, EMS45-73, l(2R)EMS45-73, GroupIII, l(2R)A', IR3, l(2Rh)IR3, l(2)IR3" "IPR000644:CBS domain, IPR018490:Cyclic nucleotide-binding-like, IPR000595:Cyclic nucleotide-binding domain, IPR002550:Domain of unknown function DUF21, IPR014710:RmlC-like jelly roll fold" CG42595 11-Aug-17 DroID_v2017_08 "Drer\cnnm3, Drer\LOC100329789, Drer\cnnm2a, Drer\LOC103911794, Drer\cnnm2b, Drer\LOC100150651, Drer\cnnm1" Scer\MAM3 "Cele\cnnm-2, Cele\cnnm-3, Cele\cnnm-5, Cele\cnnm-1" "Xtro\cnnm3, Xtro\cnnm1, Xtro\cnnm4, Xtro\cnnm2" "Mmus\Cnnm1, Mmus\Cnnm4, Mmus\Cnnm3, Mmus\Cnnm2" "Hsap\CNNM4, Hsap\CNNM2, Hsap\CNNM1, Hsap\CNNM3" DRSC20784 E 0.324145589 -0.47199125 1.019273922 -2.698217311 0.095512157 0.056224184 FBgn0039856 CG1774 - http://flybase.org/reports/FBgn0039856 protein_coding_gene acyl-CoA hydrolase activity ; GO:0047617 | inferred from sequence or structural similarity with MGI:MGI:1928939 acyl-CoA metabolic process ; GO:0006637 | inferred from sequence or structural similarity with MGI:MGI:1928939 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:1928939 CG1774 "IPR029069:HotDog domain, IPR033120:Hotdog acyl-CoA thioesterase (ACOT)-type domain" CG1774 11-Aug-17 DroID_v2017_08 "Drer\acot9.2, Drer\acot11b, Drer\acot7, Drer\acot12, Drer\acot11a, Drer\acot9.1" - "Cele\T07D3.9, Cele\F57F4.1, Cele\T22B7.7" "Xtro\acot11, Xtro\acot7, Xtro\acot9, Xtro\acot12" "Mmus\Acot7, Mmus\Acot9, Mmus\Acot12, Mmus\Acot11, Mmus\Acot10" "Hsap\ACOT12, Hsap\ACOT7, Hsap\ACOT9, Hsap\ACOT11" viable FBgn0015571 alpha-Est3 alpha-Esterase-3 http://flybase.org/reports/FBgn0015571 - protein_coding_gene - - - "alpha-Ests, alpha-Est3, alphaE3, aE3, B, CG1257, DmalphaE3" "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG1257 11-Aug-17 DroID_v2017_08 "Drer\nlgn2a, Drer\nlgn2b, Drer\cel.1, Drer\nlgn4b, Drer\nlgn3a, Drer\nlgn4a, Drer\ces2, Drer\cell, Drer\si:ch211-93f2.1, Drer\ces3, Drer\nlgn1, Drer\nlgn3b" - "Cele\F56C11.6, Cele\F07C4.12, Cele\K11G9.3, Cele\F15A8.6, Cele\T28C12.5, Cele\C52A10.1, Cele\Y71H2AM.13, Cele\B0238.7, Cele\F13H6.3, Cele\B0238.1, Cele\T28C12.4" "Xtro\cel, Xtro\nlgn2, Xtro\nlgn4x, Xtro\ces3, Xtro\nlgn3, Xtro\ces2, Xtro\LOC100494782" "Mmus\Ces2a, Mmus\Nlgn1, Mmus\Ces2b, Mmus\Ces2g, Mmus\Ces1f, Mmus\Ces5a, Mmus\Ces3b, Mmus\Ces1e, Mmus\Ces1g, Mmus\Ces2h, Mmus\Ces2f, Mmus\Ces2e, Mmus\Ces3a, Mmus\Nlgn2, Mmus\Cel, Mmus\Ces1b, Mmus\Ces1c, Mmus\Ces1h, Mmus\Nlgn3, Mmus\Ces4a, Mmus\Ces1d, Mmus\Ces2c" "Hsap\CES5A, Hsap\CES1, Hsap\CES3, Hsap\NLGN4Y, Hsap\NLGN3, Hsap\NLGN1, Hsap\CES4A, Hsap\CEL, Hsap\NLGN4X, Hsap\NLGN2, Hsap\CES2" "viable,fertile" FBgn0034585 Rbpn-5 Rabaptin-5 http://flybase.org/reports/FBgn0034585 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab5 zinc ion binding ; GO:0008270 | inferred from sequence model regulation of endosome size ; GO:0051036 | inferred from mutant phenotype inferred from genetic interaction with Rabex-5 early endosome ; GO:0005769 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG4030, Rbpn-5" "IPR000306:FYVE zinc finger, IPR001841:Zinc finger, RING-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR015390:Rabaptin, GTPase-Rab5 binding domain, IPR017455:Zinc finger, FYVE-related, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4030 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-264d12.5, Drer\rabep2, Drer\rabep1" Scer\PIB2 "Cele\rabn-5, Cele\eea-1" "Xtro\eea1, Xtro\rabep1" "Mmus\Eea1, Mmus\Rabep2, Mmus\Rabep1" "Hsap\RABEP2, Hsap\EEA1, Hsap\RABEP1" "visible,planar polarity defective,viable,lethal - all die before end of P-stage,developmental rate defective,neoplasia" "early endosomeptc-559.1,wing vein,wing hair,notal microchaeta,trichome,trichogen cell,wing disc | larval stage" FBgn0250842 CG17575 - http://flybase.org/reports/FBgn0250842 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern protein localization ; GO:0008104 | inferred from mutant phenotype sperm competition ; GO:0046692 | inferred from direct assay regulation of female receptivity, post-mating ; GO:0046008 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "CG17575, anon-SAGE:Wang-113" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain" CG17575 11-Aug-17 DroID_v2017_08 "Drer\glipr2, Drer\crispld1b, Drer\glipr2l, Drer\r3hdml, Drer\pi15b, Drer\LOC100536500, Drer\LOC101883528, Drer\crispld1a, Drer\pi15a, Drer\glipr1b, Drer\crispld2" "Scer\PRY2, Scer\PRY1, Scer\PRY3" "Cele\scl-12, Cele\scl-13, Cele\scl-1, Cele\scl-8, Cele\scl-2, Cele\scl-6, Cele\scl-15, Cele\scl-21, Cele\scl-11, Cele\scl-18, Cele\scl-17, Cele\scl-23, Cele\scl-10, Cele\scl-3, Cele\vap-2, Cele\scl-5, Cele\scl-19, Cele\scl-20, Cele\scl-9, Cele\scl-14, Cele\scl-7" "Xtro\MGC108118, Xtro\crisp3, Xtro\pi15, Xtro\crispld2, Xtro\crisp2, Xtro\r3hdml, Xtro\glipr2, Xtro\crisp1" "Mmus\Crisp4, Mmus\Glipr1, Mmus\Clec18a, Mmus\Glipr2, Mmus\Crispld1, Mmus\Crisp2, Mmus\Crispld2, Mmus\Crisp1, Mmus\Pi15, Mmus\Pi16, Mmus\Crisp3, Mmus\R3hdml, Mmus\Glipr1l2, Mmus\Glipr1l1, Mmus\Nr0b2" "Hsap\CRISP1, Hsap\GLIPR2, Hsap\CRISPLD2, Hsap\PI16, Hsap\CLEC18A, Hsap\PI15, Hsap\GLIPR1L2, Hsap\CLEC18B, Hsap\CRISPLD1, Hsap\R3HDML, Hsap\CRISP2, Hsap\CLEC18C, Hsap\GLIPR1L1, Hsap\GLIPR1, Hsap\NR0B2" FBgn0043575 PGRP-SC2 Peptidoglycan recognition protein SC2 http://flybase.org/reports/FBgn0043575 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with UniProtKB:O76537 N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | inferred from sequence or structural similarity with PGRP-SC1b peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 negative regulation of innate immune response ; GO:0045824 | inferred from direct assay peptidoglycan catabolic process ; GO:0009253 | inferred from sequence or structural similarity with PGRP-SC1b extracellular region ; GO:0005576 | inferred from sequence or structural similarity "pgrp-sc, PGRP-SC, CG14745, PGRP-SC2, CG14745 PGRP, PCRP-SC2, pgrp-sc2" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR017331:Peptidoglycan recognition protein, PGRP-S" CG14745 11-Aug-17 DroID_v2017_08 "Drer\pglyrp6, Drer\pglyrp2, Drer\pglyrp5" - - "Xtro\pglyrp1, Xtro\pglyrp1, Xtro\pglyrp2" "Mmus\Pglyrp4, Mmus\Pglyrp1, Mmus\Pglyrp3, Mmus\Pglyrp2" "Hsap\PGLYRP2, Hsap\PGLYRP4, Hsap\PGLYRP3, Hsap\PGLYRP1" "long lived,RU486 conditional,viable" "intestinal stem cell,RU486 conditional" FBgn0035421 CG12034 - http://flybase.org/reports/FBgn0035421 protein_coding_gene - - - "nSMase, CG12034" IPR005135:Endonuclease/exonuclease/phosphatase CG12034 11-Aug-17 DroID_v2017_08 "Drer\smpd2a, Drer\smpd2b" Scer\ISC1 Cele\T27F6.6 Xtro\smpd2 Mmus\Smpd2 Hsap\SMPD2 FBgn0085420 DIP-delta Dpr-interacting protein delta http://flybase.org/reports/FBgn0085420 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CT35147, CG15214, CT15465, CG4814, 34391, DIP-delta, CG34391" "IPR013098:Immunoglobulin I-set, IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype" CG34391 11-Aug-17 DroID_v2017_08 "Drer\opcml, Drer\jam2a, Drer\si:ch211-215e19.3, Drer\vsig8b, Drer\ush2a, Drer\cxcr3.1, Drer\kirrel3b, Drer\gpa33, Drer\esama, Drer\dscama, Drer\sdk1b, Drer\mxra8b, Drer\mxra8a, Drer\LOC100151468, Drer\esamb, Drer\zgc:153073, Drer\itgb4, Drer\jam2b, Drer\kirrelb, Drer\igsf9bb, Drer\lrit1a, Drer\sdk1a, Drer\ntm, Drer\pigrl4.2, Drer\ncam1b, Drer\si:ch1073-459j12.1, Drer\si:ch211-9d9.7, Drer\lrit3b, Drer\kirrel3l, Drer\paplna, Drer\f11r.2, Drer\negr1, Drer\f11r.1, Drer\kirrela, Drer\jam3a, Drer\igsf11, Drer\lsamp, Drer\si:dkey-65b12.12, Drer\si:dkey-250k15.10, Drer\cxadr, Drer\lrit3a, Drer\si:zfos-1011f11.1, Drer\zgc:110372, Drer\kirrel3a, Drer\jam3b, Drer\igsf9a, Drer\lrit1b, Drer\vsig8a" - "Cele\rig-5, Cele\zig-4" "Xtro\negr1, Xtro\lrit3, Xtro\kirrel2, Xtro\papln, Xtro\ntm, Xtro\igsf9b, Xtro\lsamp" "Mmus\Igsf9b, Mmus\Clmp, Mmus\Gpa33, Mmus\Kirrel3, Mmus\Ptprq, Mmus\Jam2, Mmus\Vsig1, Mmus\Iglon5, Mmus\Opcml, Mmus\Esam, Mmus\Sdk1, Mmus\Gm1123, Mmus\Jam3, Mmus\Igsf5, Mmus\Kirrel2, Mmus\Hepacam2, Mmus\Vsir, Mmus\F11r, Mmus\Mxra8, Mmus\Vsig2, Mmus\Lrit3, Mmus\Negr1, Mmus\Papln, Mmus\Cxadr, Mmus\Kirrel, Mmus\Igsf11, Mmus\Lrit1, Mmus\Vsig8, Mmus\Ntm, Mmus\Lsamp" "Hsap\IGSF5, Hsap\LRIT1, Hsap\C1orf204, Hsap\LRIT3, Hsap\NTM, Hsap\IGSF9B, Hsap\JAM3, Hsap\VSIG2, Hsap\KIRREL3, Hsap\C10orf54, Hsap\GPA33, Hsap\KIRREL, Hsap\USH2A, Hsap\ESAM, Hsap\JAM2, Hsap\PAPLN, Hsap\SDK1, Hsap\MXRA8, Hsap\NEGR1, Hsap\F11R, Hsap\LSAMP, Hsap\KIRREL2, Hsap\VSIG8, Hsap\IGLON5, Hsap\VSIG1, Hsap\OPCML, Hsap\CXADR, Hsap\IGSF11, Hsap\CLMP" viable DRSC29675 K -0.990768174 0.592195051 0.027897885 1.177903176 1.637429362 -0.953382359 FBgn0003189 r rudimentary http://flybase.org/reports/FBgn0003189 "FBgn0003548, FBgn0026833, FBgn0042228" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR005479, InterPro:IPR011761, InterPro:IPR013815, InterPro:IPR013816 amino acid binding ; GO:0016597 | inferred from electronic annotation with InterPro:IPR006130, InterPro:IPR006131 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011761 dihydroorotase activity ; GO:0004151 | inferred from mutant phenotype carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity ; GO:0004088 | inferred from direct assay dihydroorotase activity ; GO:0004151 | inferred from direct assay glutamine binding ; GO:0070406 | inferred by curator from GO:0004088 aspartate carbamoyltransferase activity ; GO:0004070 | inferred from mutant phenotype ATP binding ; GO:0005524 | inferred by curator from GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity ; GO:0004088 | inferred from mutant phenotype aspartate carbamoyltransferase activity ; GO:0004070 | inferred from direct assay" 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from mutant phenotype glutamine metabolic process ; GO:0006541 | inferred by curator from GO:0004088 glutamine metabolic process ; GO:0006541 | inferred from mutant phenotype - "r, CAD, GAT, DHO, CPS, ACT, CG18572, Su(b), DRORUD, PYR1, csp2, fs(1)M34, l(1)Ab, fs(1)829, CG4601" "IPR002082:Aspartate carbamoyltransferase, IPR002195:Dihydroorotase, conserved site, IPR002474:Carbamoyl-phosphate synthase, small subunit N-terminal domain, IPR005479:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain, IPR005480:Carbamoyl-phosphate synthetase, large subunit oligomerisation domain, IPR005483:Carbamoyl-phosphate synthase large subunit, CPSase domain, IPR006130:Aspartate/ornithine carbamoyltransferase, IPR006131:Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain, IPR006132:Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding, IPR006274:Carbamoyl-phosphate synthase, small subunit, IPR006275:Carbamoyl-phosphate synthase, large subunit, IPR006680:Amidohydrolase-related, IPR011607:Methylglyoxal synthase-like domain, IPR011761:ATP-grasp fold, IPR011059:Metal-dependent hydrolase, composite domain, IPR016185:Pre-ATP-grasp domain, IPR017926:Glutamine amidotransferase, IPR029062:Class I glutamine amidotransferase-like, IPR032466:Metal-dependent hydrolase" CG18572 11-Aug-17 DroID_v2017_08 "Drer\cad, Drer\cps1" "Scer\CPA2, Scer\URA2" Cele\pyr-1 "Xtro\cad, Xtro\cps1" "Mmus\Cps1, Mmus\Cad" "Hsap\CPS1, Hsap\CAD" "visible,recessive,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,auxotroph,female fertile,wild-type,lethal,rescuable maternal effect,male fertile,viable,reduced,chemical sensitive,cold sensitive,partially lethal - majority die,conditional,poor,chemical resistant" "wing,posterior wing margin,wing margin bristle,rescuable maternal effect,egg,maternal effect,ovary,wing vein,wing vein L4" DRSC19814 I 2.0685602 0.028824778 0.887028118 -0.133973838 -0.286792775 0.378759217 FBgn0022764 Sin3A Sin3A http://flybase.org/reports/FBgn0022764 "FBgn0010646, FBgn0015704, FBgn0020289, FBgn0024589, FBgn0024647" protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Mnt RNA polymerase II transcription corepressor activity ; GO:0001106 | inferred from biological aspect of ancestor with PANTHER:PTN000269659 chromatin binding ; GO:0003682 | inferred from direct assay transcription cofactor activity ; GO:0003712 | non-traceable author statement histone deacetylase activity ; GO:0004407 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000269659 "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000269659 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype negative regulation of epithelial cell migration ; GO:0010633 | inferred from genetic interaction with Csk epithelial cell migration ; GO:0010631 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from expression pattern histone deacetylation ; GO:0016575 | inferred from biological aspect of ancestor with PANTHER:PTN000269659 negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with pan regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement neuron development ; GO:0048666 | inferred from mutant phenotype" polytene chromosome ; GO:0005700 | inferred from direct assay euchromatin ; GO:0000791 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay Sin3 complex ; GO:0016580 | non-traceable author statement transcriptional repressor complex ; GO:0017053 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay Sin3 complex ; GO:0016580 | inferred from biological aspect of ancestor with PANTHER:PTN000961018 Sin3-type complex ; GO:0070822 | inferred from direct assay "Sin3A, SIN3, Sin3, CG8815, sin3, Sin 3A, dSin3A, dSin3, EY2-9, 97/15, 27/3, ES2-3, 159A11T, ld, sni3, l(2)k09715, l(2)k05415, l(2)k02703, l(2)08269, ESTS:159A11T, SIN3A, Sin3a, sin3A, sin3a" "IPR003822:Paired amphipathic helix, IPR013194:Histone deacetylase interacting domain, IPR031693:Sin3, C-terminal" CG8815 11-Aug-17 DroID_v2017_08 "Drer\sin3ab, Drer\sin3aa, Drer\sin3b" Scer\SIN3 Cele\sin-3 "Xtro\sin3b, Xtro\sin3a" "Mmus\Sin3b, Mmus\Sin3a" "Hsap\SIN3B, Hsap\SIN3A" embryonic stage

ubiquitous "visible,lethal,recessive,chemical resistant,long lived,chemical conditional,locomotor behavior defective,developmental rate defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,wild-type,partially lethal - majority die,some die during pupal stage,lethal - all die before end of larval stage,heat sensitive,some die during larval stage,hypoplasia,somatic clone,cell migration defective" "wing blade,crystal cell,mitochondrion, with Sin3Aa.cPa,heart primordium,mitochondrion, with Sin3AcPa,eye,somatic clone,photoreceptor cell,pigment cell,trichogen cell,mesothoracic tergum,wing disc,wing vein,wing vein L5" DRSC07552 IEK -1.288607575 2.650463385 -1.85481116 0.784141084 0.755577454 1.831601205 FBgn0028968 gammaCOP Coat Protein (coatomer) gamma http://flybase.org/reports/FBgn0028968 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR013040 "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR009028, InterPro:IPR013040, InterPro:IPR015873 chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype" COPI vesicle coat ; GO:0030126 | inferred from electronic annotation with InterPro:IPR013040 Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay cis-Golgi network ; GO:0005801 | inferred from direct assay "gammaCOP, gamma-COP, copg, gammaCop, l(3)S057302, 573.02, 0573/02, CG1528, anon-WO0118547.334, l(3)S057302b, COPIgamma" "IPR002553:Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR011989:Armadillo-like helical, IPR013040:Coatomer, gamma subunit, appendage, Ig-like subdomain, IPR013041:Coatomer/clathrin adaptor appendage, Ig-like subdomain, IPR009028:Coatomer/calthrin adaptor appendage, C-terminal subdomain, IPR016024:Armadillo-type fold, IPR017106:Coatomer gamma subunit, IPR032154:Coatomer subunit gamma, C-terminal" CG1528 11-Aug-17 DroID_v2017_08 "Drer\copg2, Drer\si:dkey-117n7.5" Scer\SEC21 Cele\T14G10.5 "Xtro\copg1, Xtro\copg2" "Mmus\Copg1, Mmus\Copg2" "Hsap\COPG2, Hsap\COPG1" "lethal - all die before end of embryonic stage,recessive,lethal,some die during embryonic stage,viable,fertile,small body,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval dorsal trunk,embryonic/larval lateral trunk,embryonic/larval salivary gland,endoplasmic reticulum,embryonic/first instar larval cuticle,denticle belt,embryonic/larval dorsal branch,presumptive embryonic/larval nervous system,onion stage spermatid" DRSC16955 E 0.258494585 -0.145864736 2.646508233 -3.808535445 -1.015292077 -1.269648134 FBgn0041138 l(2)44Dd lethal (2) 44Dd http://flybase.org/reports/FBgn0041138 gene - - - l(2)44Dd - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0036801 MYPT-75D MYPT-75D http://flybase.org/reports/FBgn0036801 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw myosin phosphatase regulator activity ; GO:0017020 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "CG6896, MYPT-75D, MYPT75D, Mypt-75d" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG6896 11-Aug-17 DroID_v2017_08 "Drer\ppp1r12c, Drer\nfkbie, Drer\ppp1r16b, Drer\ppp1r27a, Drer\cttnbp2nla, Drer\cttnbp2, Drer\ppp1r12a, Drer\nrarpb, Drer\cttnbp2nlb, Drer\ppp1r16a, Drer\nrarpa, Drer\LOC101885790" Scer\YCR051W "Cele\T16G1.9, Cele\gfi-2, Cele\C49H3.6, Cele\F34D10.6" "Xtro\ppp1r16a, Xtro\ppp1r16b, Xtro\cttnbp2nl, Xtro\ppp1r27, Xtro\nfkbie, Xtro\nrarp, Xtro\ppp1r12a, Xtro\ppp1r12c" "Mmus\Ankrd6, Mmus\Ppp1r27, Mmus\Ppp1r12a, Mmus\Nrarp, Mmus\Ppp1r12b, Mmus\Ppp1r16a, Mmus\Ppp1r16b, Mmus\Nfkbie, Mmus\Ppp1r12c, Mmus\Cttnbp2nl" "Hsap\PPP1R12B, Hsap\NFKBIE, Hsap\PPP1R12C, Hsap\PPP1R16A, Hsap\NRARP, Hsap\PPP1R27, Hsap\PPP1R16B, Hsap\PPP1R12A" "visible,cell polarity defective,somatic clone,lethal" "wing,oocyte,somatic clone" FBgn0010768 sqz squeeze http://flybase.org/reports/FBgn0010768 FBgn0061743 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 dendrite guidance ; GO:0070983 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - "CG5557, l(3)02102, anon-WO0118547.697, sqz, Sqz, SQZ, squeeze" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5557 11-Aug-17 DroID_v2017_08 "Drer\LOC100333031, Drer\si:dkey-261j4.3, Drer\zgc:112998, Drer\si:dkey-261j4.4, Drer\si:ch73-40a17.4, Drer\LOC101883594, Drer\si:ch211-198a12.6, Drer\drl, Drer\znf362a, Drer\LOC100537317, Drer\zbtb24, Drer\LOC103911016, Drer\si:ch211-154o6.2, Drer\znf384l, Drer\si:dkey-34m19.3, Drer\si:dkey-261j4.5, Drer\si:ch211-241b2.4, Drer\LOC560148, Drer\LOC100330167, Drer\si:ch211-276c2.4, Drer\LOC100538142, Drer\LOC108179164, Drer\si:ch211-155e24.3, Drer\si:dkey-262g12.3, Drer\wu:fe17e08, Drer\zgc:165514, Drer\LOC101883230, Drer\si:ch73-299h12.9, Drer\LOC103909987, Drer\LOC799968, Drer\im:7141269, Drer\zgc:171673, Drer\si:ch211-222k6.2" Scer\AZF1 "Cele\Y56A3A.28, Cele\scrt-1, Cele\klf-3, Cele\Y48G8AL.10, Cele\egrh-1, Cele\ztf-6, Cele\che-1, Cele\lin-29" "Xtro\znf362, Xtro\znf384, Xtro\znf367, Xtro\znf217" "Mmus\Zbtb24, Mmus\Zfp637, Mmus\Zfp367, Mmus\Zfp384, Mmus\Zfp362, Mmus\Zfp853" "Hsap\ZNF384, Hsap\ZNF367, Hsap\ZNF705A, Hsap\ZNF79, Hsap\ZNF32, Hsap\ZNF561, Hsap\ZNF850, Hsap\ZNF362, Hsap\ZNF853, Hsap\ZNF454" "lethal,locomotor behavior defective,partially,recessive,female sterile,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,viable,wild-type,somatic clone" "wing,embryonic/larval neuron,ventral nerve cord,proboscis,embryonic/larval muscle system,dorsal appendage,ovariole,germline clone,Tv neuron,neuroblast NB3-3,EL neuron,supernumerary,adult antennal lobe projection neuron DM5 lPN,somatic clone,wing hinge,tarsal segment,ventral nerve cord commissure,longitudinal connective" FBgn0060395 l(3)S132312 lethal (3) S132312 http://flybase.org/reports/FBgn0060395 gene - - - "1323/12, l(3)S132312" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0027625 tx-like taxi-like http://flybase.org/reports/FBgn0027625 - gene - - - "Txl, tx-like, txl" - - 11-Aug-17 DroID_v2017_08 - - - - - - "viable,partially lethal - majority live,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0005399 costakink costakink http://flybase.org/reports/FBgn0005399 "FBgn0000381, FBgn0001481, FBgn0001482" gene - - - "l(1)10Aa, l(1)BP4, 68, l(1)dsS53, l(1)L68, l(1)G6, l(1)F120, l(1)10Ab, csk, costakink" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,visible,partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage,viable,male,female,reduced,male fertile,female fertile,lethal - all die before end of larval stage,some die during larval stage" "costal vein,wing,wing vein L1,eye" FBgn0033692 wash washout http://flybase.org/reports/FBgn0033692 protein_coding_gene alpha-tubulin binding ; GO:0043014 | inferred from electronic annotation with InterPro:IPR028290 GTPase binding ; GO:0051020 | inferred from physical interaction with Rho1 protein binding ; GO:0005515 | inferred from physical interaction with spir "microtubule bundle formation ; GO:0001578 | inferred from direct assay Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from direct assay prepupal development ; GO:0035210 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from direct assay actin crosslink formation ; GO:0051764 | inferred from direct assay retrograde transport, endosome to Golgi ; GO:0042147 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype" WASH complex ; GO:0071203 | inferred from direct assay early endosome ; GO:0005769 | inferred from electronic annotation with InterPro:IPR028290 WASH complex ; GO:0071203 | inferred from sequence or structural similarity with UniProtKB:A8K0Z3 cytoplasm ; GO:0005737 | inferred from direct assay endosome ; GO:0005768 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with Trf2 filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "WASH, wash, p63, p65, CG13176, Wash" "IPR028290:WASH1, IPR021854:WASH1, WAHD domain" CG13176 11-Aug-17 DroID_v2017_08 Drer\wash1 - Cele\ddl-2 Xtro\wash1 Mmus\Wash1 Hsap\WASHC1 "viable,fertile,visible,recessive,large body,cell lethal,germline clone,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die during embryonic stage" "anterior pupal spiracle,prepupa,embryonic/larval dorsal trunk,oocyte | oogenesis stage S7" FBgn0035670 CG10472 - http://flybase.org/reports/FBgn0035670 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP78, anon-WO0140519.101, CG10472" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG10472 11-Aug-17 DroID_v2017_08 "Drer\zgc:112302, Drer\zgc:112160, Drer\ctrb1, Drer\ela3l, Drer\zgc:171592, Drer\LOC562139, Drer\zgc:92041, Drer\zgc:112285, Drer\zgc:112368, Drer\zgc:92745" - "Cele\svh-1, Cele\try-1" - "Mmus\Ctrc, Mmus\Cela1, Mmus\Cela3a, Mmus\Ctrl, Mmus\Cela3b, Mmus\Cela2a, Mmus\Ctrb1" "Hsap\CTRB2, Hsap\CTRB1, Hsap\CTRC" viable DRSC25310 K 0.233552443 0.563572955 0.231570206 0.055564297 -0.193515758 1.733716112 FBgn0082598 akirin akirin http://flybase.org/reports/FBgn0082598 protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from mutant phenotype transcription cofactor activity ; GO:0003712 | inferred from genetic interaction with twi inferred from physical interaction with twi" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of innate immune response ; GO:0045088 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype brahma complex ; GO:0035060 | colocalizes_with inferred from physical interaction with Bap60 inferred from physical interaction with Bap55 nucleus ; GO:0005634 | inferred from direct assay nuclear euchromatin ; GO:0005719 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "EP(3)0906, CG8580, anon-WO0118547.397, akirin, Akirin, DmAkirin, bhr" IPR024132:Akirin CG8580 11-Aug-17 DroID_v2017_08 "Drer\akirin2, Drer\akirin1" - Cele\akir-1 "Xtro\akirin1, Xtro\akirin2" "Mmus\Akirin1, Mmus\Akirin2" "Hsap\AKIRIN1, Hsap\AKIRIN2" "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,immune response defective" embryonic/larval somatic muscle FBgn0030882 GSS Glutathione Synthetase http://flybase.org/reports/FBgn0030882 protein_coding_gene "glutathione synthase activity ; GO:0004363 | inferred from electronic annotation with InterPro:IPR004887, InterPro:IPR005615, InterPro:IPR014042, InterPro:IPR014049 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR004887, InterPro:IPR005615, InterPro:IPR013816, InterPro:IPR014042, InterPro:IPR014049" "cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype glutathione biosynthetic process ; GO:0006750 | inferred from electronic annotation with InterPro:IPR004887, InterPro:IPR005615, InterPro:IPR014042 response to ethanol ; GO:0045471 | inferred from mutant phenotype detoxification of arsenic-containing substance ; GO:0071722 | inferred from genetic interaction with CG32495" - "CG32497, CG33065, CG6835, GS, 6835, GSS" "IPR004887:Glutathione synthase, substrate-binding, eukaryotic, IPR005615:Glutathione synthase, IPR014042:Glutathione synthase, alpha-helical, eukaryotic, IPR016185:Pre-ATP-grasp domain, IPR014049:Glutathione synthase, N-terminal, eukaryotic, IPR014709:Glutathione synthase domain" CG6835 11-Aug-17 DroID_v2017_08 Drer\gss Scer\GSH2 Cele\gss-1 Xtro\gss Mmus\Gss Hsap\GSS FBgn0003116 pn prune http://flybase.org/reports/FBgn0003116 - protein_coding_gene pyrophosphatase activity ; GO:0016462 | inferred from electronic annotation with InterPro:IPR004097 cyclic-nucleotide phosphodiesterase activity ; GO:0004112 | inferred from direct assay positive regulation of mitochondrial DNA replication ; GO:0090297 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype cAMP catabolic process ; GO:0006198 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype pteridine metabolic process ; GO:0019889 | inferred from mutant phenotype negative regulation of cAMP-mediated signaling ; GO:0043951 | inferred from mutant phenotype mitochondrial matrix ; GO:0005759 | inferred from direct assay "pn, EG:152A3.5, CG3461, TcD37, N4, N3" "IPR001667:DDH domain, IPR004097:DHHA2 domain" CG3461 11-Aug-17 DroID_v2017_08 "Drer\atcayb, Drer\prune2, Drer\bnip2, Drer\bnipl, Drer\prune" Scer\PPX1 - "Xtro\prune2, Xtro\bnip2, Xtro\bnipl, Xtro\prune, Xtro\atcay" "Mmus\Atcay, Mmus\Bnip2, Mmus\Prune2, Mmus\Bnipl, Mmus\Prune1" "Hsap\PRUNE2, Hsap\BNIP2, Hsap\BNIPL, Hsap\PRUNE1" embryonic stage -- adult stage "visible,recessive,eye color defective,wild-type,lethal,heat sensitive,viable" "pigment cell,heat sensitive" FBgn0033214 CG1941 - http://flybase.org/reports/FBgn0033214 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR007130" - - CG1941 IPR007130:Diacylglycerol acyltransferase CG1941 11-Aug-17 DroID_v2017_08 "Drer\mogat3b, Drer\dgat2, Drer\mogat3a, Drer\mogat2" Scer\DGA1 "Cele\Y53G8B.2, Cele\K07B1.4, Cele\dgat-2, Cele\dgtr-1" "Xtro\dgat2l6, Xtro\mogat3, Xtro\mogat1, Xtro\awat1, Xtro\mogat2.1, Xtro\dgat2" "Mmus\Dgat2, Mmus\Dgat2l6, Mmus\Mogat1, Mmus\Mogat2, Mmus\Awat1, Mmus\Awat2" "Hsap\MOGAT3, Hsap\DGAT2L6, Hsap\AWAT2, Hsap\MOGAT2, Hsap\MOGAT1, Hsap\DGAT2, Hsap\AWAT1" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0037569 tex tex http://flybase.org/reports/FBgn0037569 protein_coding_gene - mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000520027 microtubule associated complex ; GO:0005875 | inferred from direct assay THO complex part of transcription export complex ; GO:0000445 | inferred from biological aspect of ancestor with PANTHER:PTN000520027 transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:19072 "CG9615, tex, Thoc3, TEX1" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR011659:WD40-like Beta Propeller, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like" CG9615 11-Aug-17 DroID_v2017_08 Drer\thoc3 Scer\TEX1 Cele\thoc-3 Xtro\thoc3 Mmus\Thoc3 Hsap\THOC3 viable FBgn0031535 CG12795 - http://flybase.org/reports/FBgn0031535 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000058 - - CG12795 "IPR000058:Zinc finger, AN1-type" CG12795 11-Aug-17 DroID_v2017_08 "Drer\zfand2a, Drer\zfand1" "Scer\CUZ1, Scer\TMC1" Cele\aip-1 "Xtro\zfand2b, Xtro\zfand2a, Xtro\zfand1" "Mmus\Zfand1, Mmus\Zfand2b, Mmus\Zfand2a" "Hsap\ZFAND1, Hsap\ZFAND2B, Hsap\ZFAND2A" viable FBgn0008636 hbn homeobrain http://flybase.org/reports/FBgn0008636 "FBgn0034561, FBgn0034562, FBgn0040654, FBgn0053152" protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG10614, CG15648, CG15647, 57San, CG33152, hbn, Hbn" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG33152 11-Aug-17 DroID_v2017_08 "Drer\pax3a, Drer\pax7b, Drer\pax1b, Drer\pax9, Drer\rx1, Drer\pax6a, Drer\arxb, Drer\uncx, Drer\pax5, Drer\pax2b, Drer\pax2a, Drer\dharma, Drer\arxa, Drer\pax1a, Drer\pax8, Drer\pax10, Drer\rx3, Drer\pax6b, Drer\pax7a" - "Cele\ceh-53, Cele\pax-2, Cele\ceh-86, Cele\ceh-54, Cele\unc-4, Cele\egl-38, Cele\alr-1, Cele\dsc-1, Cele\vab-3, Cele\pax-1, Cele\ceh-37, Cele\ceh-8" "Xtro\pax8, Xtro\pax3, Xtro\pax9, Xtro\pax2, Xtro\pax1, Xtro\arx, Xtro\pax7, Xtro\pax5, Xtro\pax6" "Mmus\Pax8, Mmus\Rhox3h, Mmus\Phox2a, Mmus\Pax1, Mmus\Rhox4c, Mmus\Arx, Mmus\Prop1, Mmus\Rhox4a, Mmus\Rhox7a, Mmus\Nkx1-2, Mmus\Rhox4e, Mmus\Isx, Mmus\Pax3, Mmus\Rhox4f, Mmus\Pax7, Mmus\Rhox11, Mmus\Rhox4b, Mmus\Rhox2d, Mmus\Pax2, Mmus\Rhox4a2, Mmus\Rhox8, Mmus\Rhox9, Mmus\Rhox4d, Mmus\Rhox10, Mmus\Rhox3a, Mmus\Rhox3a2, Mmus\Pax5, Mmus\Pax4, Mmus\Rhox12, Mmus\Rhox4g, Mmus\Rhox13, Mmus\Uncx, Mmus\Rhox6, Mmus\Rhox3e, Mmus\Pax6, Mmus\Rhox3g, Mmus\Rhox3f, Mmus\Pax9, Mmus\Rhox2a, Mmus\Phox2b, Mmus\Rhox3c, Mmus\Rhox1" "Hsap\ESX1, Hsap\RHOXF2, Hsap\UNCX, Hsap\PHOX2A, Hsap\PAX6, Hsap\ISX, Hsap\PAX8, Hsap\PAX3, Hsap\PAX4, Hsap\PROP1, Hsap\ARX, Hsap\PHOX2B, Hsap\PAX1, Hsap\RHOXF2B, Hsap\PAX2, Hsap\RHOXF1, Hsap\RAX2, Hsap\PAX5, Hsap\PAX9, Hsap\PAX7" "lethal - all die before end of embryonic stage,some die during embryonic stage" DRSC04239 I -0.426737378 -1.676481605 -1.395950196 0.085083122 -0.491667623 0.193891244 FBgn0052062 Rbfox1 RNA-binding Fox protein 1 http://flybase.org/reports/FBgn0052062 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with ci transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from biological aspect of ancestor with PANTHER:PTN000400711 nervous system development ; GO:0007399 | inferred from mutant phenotype germarium-derived oocyte differentiation ; GO:0030706 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CG14155, BcDNA:GM06073, cg18441, CG18441, CG32062, dA2BP1, A2BP1, Rbfox1, A2bp1" "IPR000504:RNA recognition motif domain, IPR034237:FOX1, RNA recognition motif, IPR015943:WD40/YVTN repeat-like-containing domain" CG32062 11-Aug-17 DroID_v2017_08 "Drer\rbfox2, Drer\rbfox1l, Drer\rbfox1, Drer\rbfox3b, Drer\rbfox3a" - "Cele\spn-4, Cele\asd-1, Cele\fox-1" "Xtro\rbfox3, Xtro\rbfox2" "Mmus\Rbfox3, Mmus\Rbfox1, Mmus\Rbfox2" "Hsap\RBFOX3, Hsap\RBFOX2, Hsap\RBFOX1" "female sterile,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,lethal - all die before end of pupal stage,some die during pupal stage,lethal,oxidative stress response defective,female fertile,female semi-sterile,fertile" "ovary,wing cell,crossvein,ectopic,wing vein L3,wing vein L4,wing vein,somatic clone,nurse cell,female germline cell,germline clone" FBgn0022987 qkr54B quaking related 54B http://flybase.org/reports/FBgn0022987 FBgn0025570 protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay - cytoplasm ; GO:0005737 | inferred from direct assay "Sam50, p62GAP, QKR54B, SAM50, SAM, qrk54B, CG4816, qkr54B, Qrk54B" "IPR004088:K Homology domain, type 1, IPR004087:K Homology domain" CG4816 11-Aug-17 DroID_v2017_08 "Drer\khdrbs2, Drer\khdrbs3, Drer\khdrbs1b, Drer\khdrbs1a, Drer\qkib, Drer\qki2" Scer\MSL5 "Cele\E02D9.1, Cele\gld-1" "Xtro\khdrbs3, Xtro\qki, Xtro\khdrbs1, Xtro\khdrbs2" "Mmus\Khdrbs1, Mmus\Khdrbs2, Mmus\Khdrbs3, Mmus\Qk" "Hsap\KHDRBS3, Hsap\QKI, Hsap\KHDRBS2, Hsap\KHDRBS1" " adult stage | female , embryonic stage | 0-4 hr , oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

viable FBgn0029783 Sirt4 Sirtuin 4 http://flybase.org/reports/FBgn0029783 protein_coding_gene NAD+ binding ; GO:0070403 | inferred from electronic annotation with InterPro:IPR003000 histone deacetylase activity ; GO:0004407 | inferred from mutant phenotype histone deacetylation ; GO:0016575 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:14932 "dmSRT407, CG3187, dSIRT4, D.mel3, Sirt4" "IPR003000:Sirtuin family, IPR029035:DHS-like NAD/FAD-binding domain, IPR026587:Sirtuin, class II, IPR026590:Sirtuin family, catalytic core domain" CG3187 11-Aug-17 DroID_v2017_08 Drer\sirt4 Scer\HST2 "Cele\sir-2.3, Cele\sir-2.2" Xtro\sirt4 Mmus\Sirt4 Hsap\SIRT4 viable FBgn0040257 Ugt86Dc Ugt86Dc http://flybase.org/reports/FBgn0040257 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "Ugt86Dc, CG4739, AC 006491C" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG4739 11-Aug-17 DroID_v2017_08 "Drer\ugt5b4, Drer\ugt5a5, Drer\ugt8, Drer\ugt5b2, Drer\ugt1ab, Drer\ugt2b3, Drer\ugt5a2, Drer\ugt5e1, Drer\ugt1b2, Drer\ugt2b5, Drer\ugt1b7, Drer\zgc:172315, Drer\ugt2b6, Drer\ugt5b1, Drer\ugt2a6, Drer\ugt5b3, Drer\ugt2a5, Drer\ugt5g1, Drer\ugt1b5, Drer\ugt1b3, Drer\ugt5f1, Drer\ugt2b1, Drer\ugt5a1, Drer\ugt5g2, Drer\ugt5d1, Drer\ugt5a4, Drer\ugt1b4, Drer\ugt5c2, Drer\ugt5c3, Drer\ugt5b6, Drer\ugt2a2, Drer\ugt5c1" Scer\ATG26 "Cele\ugt-56, Cele\ugt-52, Cele\ugt-42, Cele\ugt-22, Cele\ugt-50, Cele\ugt-23, Cele\ugt-35, Cele\ugt-9, Cele\C03A7.12, Cele\ugt-55, Cele\ugt-40, Cele\ugt-8, Cele\ugt-5, Cele\ugt-21, Cele\ugt-14, Cele\ugt-53, Cele\H23N18.4, Cele\ugt-25, Cele\ugt-17, Cele\ugt-15, Cele\ugt-49, Cele\ugt-29, Cele\ugt-61, Cele\F10D2.8, Cele\ugt-48, Cele\ugt-20, Cele\Y43D4A.2, Cele\ugt-58, Cele\ugt-13, Cele\ugt-31, Cele\ugt-60, Cele\ugt-10, Cele\ugt-34, Cele\ugt-45, Cele\F54C1.1, Cele\ugt-39, Cele\ugt-11, Cele\K04A8.10, Cele\ugt-26, Cele\ugt-38, Cele\ugt-16, Cele\ugt-44, Cele\ugt-57, Cele\ugt-36, Cele\ugt-1, Cele\ugt-51, Cele\ugt-43, Cele\ugt-2, Cele\ugt-59, Cele\ugt-33, Cele\ugt-37, Cele\ugt-28, Cele\ugt-18, Cele\ugt-30, Cele\C23G10.6, Cele\ugt-65, Cele\ugt-6, Cele\ugt-46, Cele\ugt-12, Cele\ugt-7, Cele\ugt-24, Cele\ugt-47, Cele\ugt-4, Cele\ugt-32, Cele\ugt-27, Cele\ugt-41, Cele\ugt-62, Cele\ugt-19, Cele\C55H1.1, Cele\C03A7.13, Cele\ugt-54, Cele\ugt-3" "Xtro\ugt1a1, Xtro\ugt8, Xtro\ugt2b4, Xtro\ugt1a6, Xtro\ugt2a1, Xtro\ugt3a2" "Mmus\Ugt1a2, Mmus\Ugt1a5, Mmus\Ugt2b34, Mmus\Ugt3a1, Mmus\Ugt2b35, Mmus\Ugt1a6a, Mmus\Ugt2a3, Mmus\Ugt2a2, Mmus\Ugt1a9, Mmus\Ugt1a6b, Mmus\Ugt2b36, Mmus\Ugt8a, Mmus\Ugt3a2, Mmus\Ugt2b37, Mmus\Ugt2a1, Mmus\Ugt1a1, Mmus\Ugt2b1, Mmus\Ugt1a10, Mmus\Ugt1a7c, Mmus\Ugt2b5, Mmus\Ugt2b38" "Hsap\UGT8, Hsap\UGT2B10, Hsap\UGT1A8, Hsap\UGT1A10, Hsap\UGT3A2, Hsap\UGT2B11, Hsap\UGT1A7, Hsap\UGT1A9, Hsap\UGT1A1, Hsap\UGT1A3, Hsap\UGT2B15, Hsap\UGT2A3, Hsap\UGT2B28, Hsap\UGT2B17, Hsap\UGT2A2, Hsap\UGT3A1, Hsap\UGT2B4, Hsap\UGT1A5, Hsap\UGT1A4, Hsap\UGT1A6, Hsap\UGT2B7" "viable,fertile" FBgn0005585 Calr Calreticulin http://flybase.org/reports/FBgn0005585 "FBgn0022988, FBgn0025188" protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001580, InterPro:IPR009033, InterPro:IPR009169, InterPro:IPR018124 unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001580, InterPro:IPR009169" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001580, InterPro:IPR009169 locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement" "endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR001580, InterPro:IPR009169 fusome ; GO:0045169 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay" "CG9429, potp, clone 2.17, clone 2.11, Clr, eth, anon-EST:fe3D7, anon-EST:Liang-2.17, anon-EST:Liang-2.11, Calr, Crc, crc, chr3R:5454619..5454778" "IPR018124:Calreticulin/calnexin, conserved site, IPR001580:Calreticulin/calnexin, IPR009169:Calreticulin, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR009033:Calreticulin/calnexin, P domain" CG9429 11-Aug-17 DroID_v2017_08 "Drer\calr, Drer\calr3a, Drer\calr3b, Drer\canx" Scer\CNE1 "Cele\C05G5.3, Cele\crt-1, Cele\cnx-1" "Xtro\calr3, Xtro\calr" "Mmus\Calr4, Mmus\Canx, Mmus\Calr3, Mmus\Calr" "Hsap\CALR, Hsap\CALR3, Hsap\CANX" "viable,lethal,recessive,smell perception defective,fertile,sleep defective,chemical sensitive,chemical resistant,neuroanatomy defective" "macrochaeta,neuron,presumptive embryonic/larval peripheral nervous system,embryonic/larval neuroblast,ganglion mother cell" FBgn0037531 CG10445 - http://flybase.org/reports/FBgn0037531 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0000381 CG10445 "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain" CG10445 11-Aug-17 DroID_v2017_08 "Drer\hltf, Drer\iqca1, Drer\zgc:153738, Drer\ttf2" "Scer\ULS1, Scer\RAD16, Scer\RAD5" "Cele\F19B2.5, Cele\T23H2.3, Cele\F54E12.2" - "Mmus\Hltf, Mmus\4931409K22Rik, Mmus\Ttf2, Mmus\Iqca" "Hsap\IQCA1, Hsap\IQCA1L, Hsap\TTF2, Hsap\HLTF" viable FBgn0015010 Ag5r Antigen 5-related http://flybase.org/reports/FBgn0015010 "FBgn0030580, FBgn0044553" protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "Agr5, Agr, agr, CG9538, anon-WO0140519.74, Ag5r" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG9538 11-Aug-17 DroID_v2017_08 "Drer\LOC101883528, Drer\LOC100536500, Drer\r3hdml, Drer\crispld2, Drer\pi15b, Drer\pi15a, Drer\glipr2, Drer\glipr1b, Drer\crispld1b, Drer\glipr2l, Drer\crispld1a" "Scer\PRY1, Scer\PRY2, Scer\PRY3" "Cele\scl-7, Cele\scl-17, Cele\scl-21, Cele\scl-15, Cele\scl-14, Cele\scl-11, Cele\scl-27, Cele\scl-5, Cele\scl-19, Cele\scl-13, Cele\scl-6, Cele\scl-10, Cele\scl-1, Cele\scl-3, Cele\scl-18, Cele\scl-8, Cele\scl-20, Cele\scl-23, Cele\scl-9, Cele\scl-12, Cele\scl-2" "Xtro\MGC108118, Xtro\r3hdml, Xtro\crisp1, Xtro\pi15, Xtro\glipr2, Xtro\crisp2, Xtro\crispld2, Xtro\crisp3" "Mmus\Clec18a, Mmus\Glipr2, Mmus\Crisp2, Mmus\Glipr1l2, Mmus\Crisp3, Mmus\Pi16, Mmus\Glipr1, Mmus\Pi15, Mmus\R3hdml, Mmus\Crispld1, Mmus\Crisp4, Mmus\Crisp1, Mmus\Crispld2, Mmus\Glipr1l1" "Hsap\CRISP2, Hsap\CLEC18A, Hsap\CLEC18B, Hsap\GLIPR1L2, Hsap\R3HDML, Hsap\PI15, Hsap\PI16, Hsap\CRISPLD1, Hsap\CRISP1, Hsap\CRISPLD2, Hsap\GLIPR1L1, Hsap\GLIPR1, Hsap\CLEC18C, Hsap\GLIPR2" " adult stage | female , embryonic stage -- adult stage , adult stage | male " viable FBgn0036446 CG9384 - http://flybase.org/reports/FBgn0036446 protein_coding_gene "transferase activity, transferring hexosyl groups ; GO:0016758 | inferred from electronic annotation with InterPro:IPR006759" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006759 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006759 "CG9384, dMGAT4-1" IPR006759:Glycosyl transferase family 54 CG9384 11-Aug-17 DroID_v2017_08 "Drer\mgat4b, Drer\mgat4a, Drer\mgat4c, Drer\zgc:154054, Drer\zgc:101663" - "Cele\str-255, Cele\str-247, Cele\B0391.3, Cele\str-262, Cele\str-240, Cele\str-244, Cele\str-225, Cele\str-263, Cele\str-256, Cele\Y19D10A.1, Cele\str-228, Cele\str-238, Cele\F14H8.8, Cele\str-260, Cele\str-208, Cele\str-232, Cele\str-257, Cele\str-121, Cele\str-217, Cele\str-258, Cele\str-226, Cele\str-190, Cele\str-199, Cele\str-200" "Xtro\mgat4b, Xtro\mgat4a" "Mmus\Mgat4c, Mmus\Mgat4d, Mmus\Mgat4e, Mmus\Mgat4b, Mmus\4933406M09Rik, Mmus\Mgat4a" "Hsap\MGAT4B, Hsap\MGAT4D, Hsap\MGAT4C, Hsap\MGAT4A" viable FBgn0040250 Ugt86Dj Ugt86Dj http://flybase.org/reports/FBgn0040250 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG15902, AC 006491J, Ugt86Dj" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG15902 11-Aug-17 DroID_v2017_08 "Drer\ugt1b7, Drer\ugt5b2, Drer\ugt5b1, Drer\ugt5d1, Drer\ugt5b4, Drer\ugt2b1, Drer\ugt5a4, Drer\ugt1b2, Drer\ugt2b5, Drer\ugt5a5, Drer\ugt1ab, Drer\ugt5f1, Drer\ugt5c3, Drer\ugt5e1, Drer\ugt2b3, Drer\ugt2a5, Drer\zgc:172315, Drer\ugt2a4, Drer\ugt5g2, Drer\ugt5a1, Drer\ugt2b6, Drer\ugt1b4, Drer\ugt5b6, Drer\ugt2a6, Drer\ugt8, Drer\ugt2a2, Drer\ugt1b3, Drer\ugt1b5, Drer\ugt5g1, Drer\ugt5c2, Drer\ugt5a2, Drer\ugt5b3, Drer\ugt5c1" Scer\ATG26 "Cele\ugt-55, Cele\ugt-32, Cele\ugt-7, Cele\ugt-15, Cele\ugt-57, Cele\ugt-14, Cele\ugt-37, Cele\ugt-24, Cele\ugt-28, Cele\ugt-39, Cele\C03A7.13, Cele\H23N18.4, Cele\ugt-20, Cele\ugt-38, Cele\ugt-52, Cele\ugt-9, Cele\ugt-21, Cele\ugt-53, Cele\Y43D4A.2, Cele\ugt-49, Cele\ugt-5, Cele\ugt-22, Cele\ugt-35, Cele\ugt-26, Cele\ugt-58, Cele\ugt-40, Cele\ugt-13, Cele\ugt-2, Cele\ugt-11, Cele\ugt-16, Cele\ugt-36, Cele\ugt-41, Cele\C03A7.12, Cele\ugt-43, Cele\ugt-4, Cele\F10D2.8, Cele\ugt-23, Cele\ugt-60, Cele\ugt-48, Cele\ugt-27, Cele\ugt-10, Cele\ugt-19, Cele\ugt-44, Cele\ugt-62, Cele\ugt-3, Cele\C55H1.1, Cele\ugt-6, Cele\ugt-30, Cele\ugt-51, Cele\ugt-17, Cele\ugt-50, Cele\ugt-33, Cele\ugt-12, Cele\ugt-54, Cele\ugt-65, Cele\ugt-31, Cele\ugt-1, Cele\C23G10.6, Cele\ugt-42, Cele\K04A8.10, Cele\ugt-59, Cele\ugt-25, Cele\ugt-8, Cele\ugt-56, Cele\ugt-45, Cele\ugt-18, Cele\ugt-29, Cele\ugt-47, Cele\ugt-61, Cele\ugt-46, Cele\ugt-34" "Xtro\ugt2a1, Xtro\ugt2b4, Xtro\ugt3a2, Xtro\ugt8, Xtro\ugt1a6" "Mmus\Ugt1a1, Mmus\Ugt3a2, Mmus\Ugt2b34, Mmus\Ugt8a, Mmus\Ugt2b1, Mmus\Ugt1a6b, Mmus\Ugt1a5, Mmus\Ugt2a2, Mmus\Ugt3a1, Mmus\Ugt2b38, Mmus\Ugt2b36, Mmus\Ugt1a7c, Mmus\Ugt1a2, Mmus\Ugt1a9, Mmus\Ugt2a1, Mmus\Ugt2a3, Mmus\Ugt2b35, Mmus\Ugt1a10, Mmus\Ugt1a6a, Mmus\Ugt2b37, Mmus\Ugt2b5" "Hsap\UGT2B10, Hsap\UGT1A9, Hsap\UGT1A7, Hsap\UGT2B15, Hsap\UGT1A8, Hsap\UGT1A1, Hsap\UGT2B28, Hsap\UGT1A10, Hsap\UGT1A3, Hsap\UGT1A6, Hsap\UGT2B4, Hsap\UGT2B7, Hsap\UGT2B17, Hsap\UGT2A3, Hsap\UGT1A5, Hsap\UGT1A4, Hsap\UGT2B11, Hsap\UGT2A1, Hsap\UGT2A2, Hsap\UGT3A1, Hsap\UGT3A2, Hsap\UGT8" viable FBgn0050486 CG30486 - http://flybase.org/reports/FBgn0050486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay CG30486 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG30486 11-Aug-17 DroID_v2017_08 "Drer\crispld2, Drer\crispld1a, Drer\glipr2, Drer\glipr1b, Drer\LOC101883528, Drer\LOC100536500, Drer\crispld1b, Drer\glipr2l, Drer\pi15b, Drer\pi15a, Drer\r3hdml" "Scer\PRY2, Scer\PRY3, Scer\PRY1" "Cele\scl-1, Cele\scl-9, Cele\scl-3, Cele\vap-2, Cele\scl-7, Cele\scl-2, Cele\scl-10, Cele\scl-5, Cele\scl-19, Cele\scl-14, Cele\scl-17, Cele\scl-8, Cele\scl-11, Cele\scl-23, Cele\scl-6, Cele\scl-20, Cele\scl-13, Cele\scl-18, Cele\scl-15, Cele\scl-21, Cele\scl-12" "Xtro\r3hdml, Xtro\crisp2, Xtro\crisp1, Xtro\pi15, Xtro\crisp3, Xtro\crispld2, Xtro\glipr2, Xtro\MGC108118" "Mmus\Crisp3, Mmus\R3hdml, Mmus\Crisp1, Mmus\Glipr1l1, Mmus\Crisp4, Mmus\Crisp2, Mmus\Glipr1l2, Mmus\Crispld1, Mmus\Crispld2, Mmus\Glipr1, Mmus\Glipr2, Mmus\Pi15, Mmus\Clec18a, Mmus\Pi16" "Hsap\CRISP2, Hsap\CRISP3, Hsap\CRISP1, Hsap\CRISPLD2, Hsap\CLEC18B, Hsap\PI15, Hsap\GLIPR1, Hsap\CLEC18C, Hsap\PI16, Hsap\GLIPR2, Hsap\R3HDML, Hsap\CRISPLD1, Hsap\GLIPR1L2, Hsap\GLIPR1L1, Hsap\CLEC18A" viable FBgn0036999 isoQC iso Glutaminyl cyclase http://flybase.org/reports/FBgn0036999 protein_coding_gene glutaminyl-peptide cyclotransferase activity ; GO:0016603 | inferred from direct assay "peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase ; GO:0017186 | inferred from direct assay" extracellular region ; GO:0005576 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CG32426, isoDromeQC, isoQC, CG5976" IPR007484:Peptidase M28 CG5976 11-Aug-17 DroID_v2017_08 "Drer\qpct, Drer\qpctla, Drer\qpctlb" Scer\YFR018C Cele\H27A22.1 "Xtro\qpct, Xtro\qpctl" "Mmus\Qpctl, Mmus\Qpct" "Hsap\QPCT, Hsap\QPCTL" FBgn0030391 Rab40 Rab40 http://flybase.org/reports/FBgn0030391 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 protein localization to plasma membrane ; GO:0072659 | inferred from biological aspect of ancestor with PANTHER:PTN000635134 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 vesicle docking involved in exocytosis ; GO:0006904 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000635134 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000635134 synaptic vesicle ; GO:0008021 | inferred from biological aspect of ancestor with PANTHER:PTN001530779 "DmRab40, CG1900, Rab40, rab40, 24641533, Q8IR80" "IPR001496:SOCS box domain, IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1900 11-Aug-17 DroID_v2017_08 "Drer\rab12, Drer\rab40c, Drer\rab15, Drer\rab8b, Drer\rab40b, Drer\rab44, Drer\LOC100535415, Drer\rab10, Drer\rab13, Drer\zgc:162879, Drer\rab8a, Drer\rasef" Scer\SEC4 - "Xtro\rab28, Xtro\rab13, Xtro\rasef, Xtro\rab44, Xtro\LOC100135070, Xtro\rab8b, Xtro\rab40b, Xtro\rab40c, Xtro\rasef, Xtro\rab15, Xtro\rab8a, Xtro\rab12, Xtro\rab10" "Mmus\Rab28, Mmus\Rab8a, Mmus\Rasef, Mmus\Rab10, Mmus\Rab13, Mmus\Rab40b, Mmus\Rab44, Mmus\Rab8b, Mmus\Rab40c, Mmus\Rab15, Mmus\Rab12" "Hsap\RAB12, Hsap\RAB15, Hsap\RAB10, Hsap\RAB40AL, Hsap\RAB13, Hsap\RAB40B, Hsap\RAB40C, Hsap\RAB28, Hsap\RAB8A, Hsap\RAB40A, Hsap\RAB8B, Hsap\RASEF" "viable,fertile" DRSC19820 IE 2.394000745 1.249831291 2.524947784 0.722026501 0.483577515 -0.522709581 FBgn0028990 Spn27A Serpin 27A http://flybase.org/reports/FBgn0028990 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from direct assay enzyme inhibitor activity ; GO:0004857 | inferred from direct assay sleep ; GO:0030431 | inferred from expression pattern negative regulation of proteolysis ; GO:0045861 | inferred from direct assay negative regulation of melanization defense response ; GO:0035009 | inferred from mutant phenotype melanization defense response ; GO:0035006 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype negative regulation of melanization defense response ; GO:0035009 | traceable author statement response to wounding ; GO:0009611 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from direct assay dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype defense response to insect ; GO:0002213 | inferred from mutant phenotype melanization defense response ; GO:0035006 | traceable author statement extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 extracellular region ; GO:0005576 | inferred from direct assay "Spn27A, Dm-Spn27A, spn27A, CG11331, EST1, Spn27, sp27A, Spn27a" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG11331 11-Aug-17 DroID_v2017_08 "Drer\serpinf2a, Drer\agt, Drer\serpinf2b, Drer\serpind1, Drer\serpini1, Drer\serpinf1, Drer\serping1" - "Cele\C28G1.2, Cele\srp-2, Cele\srp-6, Cele\srp-3, Cele\srp-7, Cele\srp-1, Cele\srp-8" - "Mmus\Agt, Mmus\Serpinb7, Mmus\Serpinf2, Mmus\Serpinf1, Mmus\Serpini1, Mmus\Serpind1, Mmus\Serpina3a, Mmus\Serpini2" "Hsap\SERPINI1, Hsap\SERPINB7, Hsap\SERPINF1, Hsap\SERPINI2, Hsap\SERPINF2, Hsap\SERPIND1, Hsap\SERPINA3, Hsap\AGT" "lethal,maternal effect,viable,body color defective,hypoactive,conditional,chemical resistant,melanotic mass phenotype,immune response defective,lethal - all die before end of pupal stage,partially,some die during pupal stage,female sterile,recessive,partially lethal - majority die,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic dorsal epidermis,embryonic epidermis,embryonic/first instar larval cuticle,maternal effect,wing,melanotic mass,trachea,embryonic/larval hemolymph | third instar larval stage" FBgn0003742 tra2 transformer 2 http://flybase.org/reports/FBgn0003742 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with tra inferred from physical interaction with SF2 identical protein binding ; GO:0042802 | inferred from physical interaction with tra2 RNA binding ; GO:0003723 | non-traceable author statement pre-mRNA binding ; GO:0036002 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "female somatic sex determination ; GO:0019101 | traceable author statement spliceosomal complex assembly ; GO:0000245 | non-traceable author statement regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from direct assay reproduction ; GO:0000003 | non-traceable author statement mRNA processing ; GO:0006397 | inferred from mutant phenotype sex determination ; GO:0007530 | non-traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 mRNA splicing, via spliceosome ; GO:0000398 | non-traceable author statement mRNA processing ; GO:0006397 | non-traceable author statement spermatogenesis ; GO:0007283 | non-traceable author statement female sex determination ; GO:0030237 | inferred from mutant phenotype male somatic sex determination ; GO:0019102 | traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred from direct assay reproduction ; GO:0000003 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "TRA2, tra-2, Tra-2, Tra2, TRA-2, TRA 2, CG10128, tra2" IPR000504:RNA recognition motif domain CG10128 11-Aug-17 DroID_v2017_08 "Drer\tra2b, Drer\cirbpa, Drer\cirbpb, Drer\safb, Drer\rbmx, Drer\tra2a" - "Cele\F32B4.4, Cele\rsp-8" "Xtro\tra2a, Xtro\tra2b, Xtro\cirbp, Xtro\rbmx, Xtro\safb" "Mmus\Tra2a, Mmus\Tra2b, Mmus\Cirbp, Mmus\Safb, Mmus\Gm21704, Mmus\Rbmxl2, Mmus\Gm3376, Mmus\Gm21677, Mmus\Sltm, Mmus\Rbmxl1, Mmus\Gm4064, Mmus\Rbmy, Mmus\Gm21708, Mmus\Gm10256, Mmus\Rbmx, Mmus\Gm21693, Mmus\Rbm3" "Hsap\RBMY1D, Hsap\RBMX, Hsap\RBMY1F, Hsap\SLTM, Hsap\RBM3, Hsap\CIRBP, Hsap\RBMXL3, Hsap\RBMY1J, Hsap\RBMXL1, Hsap\RBMY1B, Hsap\RBMY1E, Hsap\TRA2B, Hsap\SAFB, Hsap\TRA2A, Hsap\SAFB2, Hsap\RBMXL2" " adult stage | female , adult stage | male " " testis

, germline cell

" "visible,heat sensitive,viable,sex-determination defective,male fertile,sterile,recessive,courtship behavior defective,female,lethal,female fertile,wild-type,male sterile,female sterile" "female genitalia,sex comb,spermatozoon,ectopic,female,female reproductive system,spermatocyte,spermatid,gonad,germline cell,heat sensitive,male repressed primordium,somatic clone,male genitalia,female analia,ovary,abdominal tergite 6,abdominal tergite 7,abdominal tergite 5,abdominal sternite 6,anal plate,female genital disc,male genital disc,adult abdomen" FBgn0036000 CG3434 - http://flybase.org/reports/FBgn0036000 protein_coding_gene queuine tRNA-ribosyltransferase activity ; GO:0008479 | contributes_to inferred from sequence or structural similarity with UniProtKB:B8ZXI1 queuine tRNA-ribosyltransferase activity ; GO:0008479 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000239043 tRNA modification ; GO:0006400 | inferred from electronic annotation with InterPro:IPR002616 queuosine biosynthetic process ; GO:0008616 | inferred from biological aspect of ancestor with PANTHER:PTN000239043 queuosine biosynthetic process ; GO:0008616 | inferred from sequence or structural similarity with UniProtKB:B8ZXI1 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000239043 CG3434 "IPR002616:tRNA-guanine(15) transglycosylase-like, IPR028592:Queuine tRNA-ribosyltransferase accessory subunit QTRTD1" CG3434 11-Aug-17 DroID_v2017_08 "Drer\txndc9, Drer\qtrtd1" Scer\PLP1 "Cele\tgt-2, Cele\txdc-9" Xtro\qtrtd1 "Mmus\Qtrtd1, Mmus\Txndc9" "Hsap\QTRT2, Hsap\TXNDC9" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0083084 l(2)42Ac l(2)42Ac http://flybase.org/reports/FBgn0083084 gene - - - l(2)42Ac - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" "wing,microchaeta" FBgn0016919 nompB no mechanoreceptor potential B http://flybase.org/reports/FBgn0016919 "FBgn0032950, FBgn0032951, FBgn0032952, FBgn0032953" protein_coding_gene molecular_function ; GO:0003674 | no biological data available non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from sequence or structural similarity with MGI:MGI:98715 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with MGI:MGI:98715 cilium assembly ; GO:0060271 | inferred from sequence model cilium assembly ; GO:0060271 | inferred from mutant phenotype intraciliary transport ; GO:0042073 | inferred from mutant phenotype intraciliary transport particle ; GO:0030990 | inferred from sequence or structural similarity with UniProtKB:Q9FPW0 cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:98715 intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:98715 non-motile cilium ; GO:0097730 | inferred from direct assay "146590_s_at, CG12548, osm-5, CG14465, nomp, CG4137, CG15190, nompB, IFT88, NOMPB, Tg737, OSM-5, NompB" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG12548 11-Aug-17 DroID_v2017_08 Drer\ift88 Scer\STI1 Cele\osm-5 Xtro\ift88 Mmus\Ift88 Hsap\IFT88 " olfactory sensory organ

, mechanosensory chaeta

, sensillum campaniformium

, chordotonal organ

" "auditory perception defective,recessive,uncoordinated,locomotor behavior defective,behavior defective,fertile,partially lethal - majority die,flight defective,viable" "wing,leg,macrochaeta,adult antennal nerve,scolopidial cilium,cilium & olfactory neuron & antennal segment 3,ciliumpeb-,olfactory receptor neuron" FBgn0037555 Ada2b transcriptional Adaptor 2b http://flybase.org/reports/FBgn0037555 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O76216 inferred from physical interaction with UniProtKB:Q9VWZ1 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000271860" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 histone H3 acetylation ; GO:0043966 | inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype polytene chromosome puffing ; GO:0035079 | NOT inferred from mutant phenotype axon target recognition ; GO:0007412 | inferred from mutant phenotype wing disc pattern formation ; GO:0035222 | inferred from genetic interaction with mam positive regulation of histone acetylation ; GO:0035066 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from direct assay" SAGA complex ; GO:0000124 | inferred from physical interaction with Spt3 inferred from physical interaction with Nipped-A SAGA complex ; GO:0000124 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "dAda2b, ada2b, dAda2S, CG9638, ADA2b, BcDNA:LD24527, Ada2S, Ada2b, dAda2B, dADA2b, Ada2B" "IPR000433:Zinc finger, ZZ-type, IPR001005:SANT/Myb domain, IPR009057:Homeobox domain-like, IPR016827:Transcriptional adaptor 2, IPR017884:SANT domain" CG9638 11-Aug-17 DroID_v2017_08 "Drer\ret, Drer\fgfr1a, Drer\tada2a, Drer\fgfr2, Drer\tada2b, Drer\fgfr4" "Scer\FUN19, Scer\YOR338W, Scer\ADA2" "Cele\F09A5.2, Cele\kin-9, Cele\ada-2, Cele\R151.1, Cele\C24G6.2, Cele\egl-15, Cele\F09G2.1" "Xtro\fgfr3, Xtro\fgfr2, Xtro\fgfr1, Xtro\tada2a, Xtro\tada2b, Xtro\fgfr4, Xtro\ret" "Mmus\Fgfr4, Mmus\Fgfr3, Mmus\Tada2a, Mmus\Fgfr2, Mmus\Tada2b, Mmus\Ret" "Hsap\FGFR3, Hsap\FGFR2, Hsap\FGFR4, Hsap\RET, Hsap\TADA2B, Hsap\TADA2A, Hsap\FGFR1" "lethal,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,germline clone,recessive,neuroanatomy defective,visible,partially lethal - majority die" "axon & photoreceptor cell R2,axon & photoreceptor cell R3,axon & photoreceptor cell R4,axon & photoreceptor cell R5,glial cell,wing disc,conditional,trichogen cell" FBgn0027359 Tim8 Tim8 http://flybase.org/reports/FBgn0027359 FBgn0062891 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProt:Q9Y5J9 inferred from sequence or structural similarity with UniProtKB:O60220 metal ion transmembrane transporter activity ; GO:0046873 | inferred from biological aspect of ancestor with PANTHER:PTN001470437 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProt:Q9Y5J9 inferred from sequence or structural similarity with UniProtKB:O60220 cation transmembrane transport ; GO:0098655 | inferred from biological aspect of ancestor with PANTHER:PTN001470437 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProt:Q9Y5J9 inferred from sequence or structural similarity with UniProtKB:O60220 mitochondrion ; GO:0005739 | inferred from direct assay membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001470437 "CG1728, BcDNA:SD06593, Tim8" IPR004217:Tim10/DDP family zinc finger CG1728 11-Aug-17 DroID_v2017_08 "Drer\timm8a, Drer\timm8b" Scer\TIM8 Cele\ddp-1 Xtro\timm8b "Mmus\Timm8a2, Mmus\Timm8a1, Mmus\Timm8b" "Hsap\TIMM8B, Hsap\TIMM8A" viable eye FBgn0033906 CG8331 - http://flybase.org/reports/FBgn0033906 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of intracellular transport ; GO:0032386 | inferred from sequence or structural similarity with MGI:MGI:1917585 endomembrane system ; GO:0012505 | inferred from direct assay "CT24597, CG8331" IPR004345:TB2/DP1/HVA22-related protein CG8331 11-Aug-17 DroID_v2017_08 "Drer\reep5, Drer\reep6, Drer\reep3b, Drer\reep1, Drer\zgc:101744, Drer\reep3a, Drer\reep2" Scer\YOP1 "Cele\yop-1, Cele\T03F6.6, Cele\Y110A2AR.1, Cele\F56B3.6" "Xtro\reep3, Xtro\reep6, Xtro\reep4, Xtro\reep5" "Mmus\Reep4, Mmus\Reep2, Mmus\Reep3, Mmus\Reep1, Mmus\Reep5, Mmus\Reep6" "Hsap\REEP1, Hsap\REEP6, Hsap\REEP2, Hsap\REEP5, Hsap\REEP3" "viable,fertile" FBgn0034081 CG10731 - http://flybase.org/reports/FBgn0034081 protein_coding_gene molecular_function ; GO:0003674 | no biological data available proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:Q99766 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with UniProtKB:Q99766" "CG33038, CG10731, ATPW" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR026063:ATP synthase subunit s, mitochondrial" CG10731 11-Aug-17 DroID_v2017_08 "Drer\ext2, Drer\atp5s" - "Cele\C05C8.1, Cele\R02D5.8, Cele\Y53G8AR.8" "Xtro\atp5s, Xtro\ext2" "Mmus\Ext2, Mmus\Atp5s, Mmus\Atp5sl" "Hsap\ATP5SL, Hsap\ATP5S, Hsap\EXT2" FBgn0032157 Etl1 Etl1 http://flybase.org/reports/FBgn0032157 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype - "CG5899, Etl1, SMARCAD1, ETL1" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5899 11-Aug-17 DroID_v2017_08 "Drer\smarcad1b, Drer\smarcad1a" Scer\FUN30 Cele\M03C11.8 Xtro\smarcad1 Mmus\Smarcad1 Hsap\SMARCAD1 "suppressor of variegation,viable" embryonic/larval hemocyte | third instar larval stage FBgn0034491 Hsl Hormone-sensitive lipase http://flybase.org/reports/FBgn0034491 protein_coding_gene lipase activity ; GO:0016298 | inferred from electronic annotation with InterPro:IPR010468 cholesterol metabolic process ; GO:0008203 | inferred from electronic annotation with InterPro:IPR010468 lipid catabolic process ; GO:0016042 | inferred from electronic annotation with InterPro:IPR010468 triglyceride mobilization ; GO:0006642 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "A, anon-56Ea, Hsl, CG11055, dHSL" "IPR010468:Hormone-sensitive lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold, IPR013094:Alpha/beta hydrolase fold-3" CG11055 11-Aug-17 DroID_v2017_08 "Drer\lipea, Drer\lipeb" - Cele\hosl-1 Xtro\lipe "Mmus\Aadac, Mmus\Lipe" Hsap\LIPE viable "embryonic/larval fat body,lipid particle" FBgn0035619 CG10592 - http://flybase.org/reports/FBgn0035619 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG10592 "IPR001952:Alkaline phosphatase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG10592 11-Aug-17 DroID_v2017_08 "Drer\alpl, Drer\alpi.2, Drer\alpi.1, Drer\alp3" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1" "Mmus\Alpl, Mmus\Alpi, Mmus\Alppl2, Mmus\Akp3" "Hsap\ALPPL2, Hsap\ALPL, Hsap\ALPP, Hsap\ALPI" "viable,fertile" FBgn0013954 FK506-bp2 FK506-binding protein 2 http://flybase.org/reports/FBgn0013954 - protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 FK506 binding ; GO:0005528 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 plasma membrane ; GO:0005886 | inferred from direct assay "Fk506-bp2, 143729_at, FKBP12, dFKBP12, FKBP, DrFKBP12, CG11001, FK506-bp2, FK506-BP2, 11001, fkbp" "IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type" CG11001 11-Aug-17 DroID_v2017_08 "Drer\fkbp1aa, Drer\si:ch211-208h16.4, Drer\fkbp2, Drer\si:ch73-199g24.2, Drer\fkbp9, Drer\fkbp10b, Drer\fkbp1ab, Drer\fkbp4, Drer\fkbp7, Drer\fkbp11, Drer\fkbp10a, Drer\fkbp14, Drer\fkbp5, Drer\fkbp1b" Scer\FPR1 "Cele\fkb-4, Cele\fkb-6, Cele\fkb-5, Cele\fkb-3, Cele\fkb-8, Cele\fkb-2" "Xtro\fkbp14, Xtro\fkbp7, Xtro\fkbp9, Xtro\fkbp3, Xtro\fkbp15, Xtro\fkbp10, Xtro\fkbp1b" "Mmus\Fkbp7, Mmus\Fkbp2, Mmus\Fkbp9, Mmus\Fkbp11, Mmus\Fkbp14, Mmus\Fkbp1a, Mmus\Fkbp10, Mmus\Fkbp3, Mmus\Fkbp1b, Mmus\Fkbp5, Mmus\Fkbp4, Mmus\Fkbp15" "Hsap\FKBP3, Hsap\FKBP14, Hsap\FKBP5, Hsap\FKBP2, Hsap\FKBP7, Hsap\FKBP9, Hsap\FKBP4, Hsap\FKBP11, Hsap\FKBP1B, Hsap\FKBP10, Hsap\FKBP1A, Hsap\FKBP15" viable FBgn0037146 CG7470 - http://flybase.org/reports/FBgn0037146 protein_coding_gene "glutamate-5-semialdehyde dehydrogenase activity ; GO:0004350 | inferred from electronic annotation with InterPro:IPR000965, InterPro:IPR020593 glutamate 5-kinase activity ; GO:0004349 | inferred from electronic annotation with InterPro:IPR019797 delta1-pyrroline-5-carboxylate synthetase activity ; GO:0017084 | inferred from sequence or structural similarity with UniProtKB:P54886" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000965, InterPro:IPR005766, InterPro:IPR015590, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163, InterPro:IPR020593 proline biosynthetic process ; GO:0006561 | inferred from sequence or structural similarity with UniProtKB:P54886 germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype" lipid particle ; GO:0005811 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:P54886 CG7470 "IPR000965:GPR domain, IPR001048:Aspartate/glutamate/uridylate kinase, IPR001057:Glutamate/acetylglutamate kinase, IPR005715:Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase, IPR005766:Delta l-pyrroline-5-carboxylate synthetase, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR019797:Glutamate 5-kinase, conserved site, IPR020593:Gamma-glutamyl phosphate reductase GPR, conserved site, IPR015590:Aldehyde dehydrogenase domain" CG7470 11-Aug-17 DroID_v2017_08 Drer\aldh18a1 "Scer\PRO1, Scer\YHR033W, Scer\PRO2" Cele\alh-13 Xtro\aldh18a1 Mmus\Aldh18a1 Hsap\ALDH18A1 viable "epithelium,egg chamber,interfollicle cell" FBgn0265935 coro coro http://flybase.org/reports/FBgn0265935 protein_coding_gene actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000091699 defense response to fungus ; GO:0050832 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from biological aspect of ancestor with PANTHER:PTN000091699 actin cytoskeleton ; GO:0015629 | inferred from biological aspect of ancestor with PANTHER:PTN000091699 mitotic spindle ; GO:0072686 | inferred from direct assay "coro, CG9446, l(2)k08011" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR015505:Coronin, IPR015048:Domain of unknown function DUF1899, IPR019775:WD40 repeat, conserved site" CG9446 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-108c6.2, Drer\si:ch73-106g13.1, Drer\coro1cb, Drer\coro2ba, Drer\coro1ca, Drer\coro1a, Drer\coro6, Drer\coro1b, Drer\coro2a, Drer\coro2bb" Scer\CRN1 Cele\cor-1 "Xtro\coro2b, Xtro\coro2a, Xtro\coro1a, Xtro\coro1c, Xtro\coro6" "Mmus\Coro2a, Mmus\Coro1a, Mmus\Coro6, Mmus\Coro1c, Mmus\Coro2b, Mmus\Coro1b" "Hsap\CORO6, Hsap\CORO1B, Hsap\CORO2B, Hsap\CORO1A, Hsap\CORO2A, Hsap\CORO1C" FBgn0035720 CG10077 - http://flybase.org/reports/FBgn0035720 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD:S000005056 "RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN001168930" microtubule associated complex ; GO:0005875 | inferred from direct assay "DmRH5, p90, cg10077, BcDNA:HL01868, BcDNA:HL07910, CG10077" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR015943:WD40/YVTN repeat-like-containing domain" CG10077 11-Aug-17 DroID_v2017_08 "Drer\LOC556764, Drer\ddx59, Drer\clk4a, Drer\clk2b, Drer\tdrd12, Drer\clk2a, Drer\clk4b, Drer\ddx21, Drer\ddx5" "Scer\DBP3, Scer\DBP2" "Cele\ddx-17, Cele\madd-3, Cele\Y54G11A.3" "Xtro\ddx59, Xtro\clk3, Xtro\ddx5, Xtro\clk1, Xtro\ddx17, Xtro\clk2, Xtro\ddx21, Xtro\gpr149" "Mmus\Tdrd12, Mmus\Ddx50, Mmus\Clk1, Mmus\Clk2, Mmus\Gpr149, Mmus\Clk4, Mmus\Clk3, Mmus\Ddx3x, Mmus\Ddx21, Mmus\Ddx59, Mmus\Ddx17, Mmus\Ddx5" "Hsap\CLK1, Hsap\CLK3, Hsap\DDX5, Hsap\TDRD12, Hsap\DDX21, Hsap\CLK2, Hsap\DDX17, Hsap\DDX43, Hsap\CLK4, Hsap\DDX50, Hsap\DDX59, Hsap\GPR149" "viable,fertile" FBgn0260748 CG5004 - http://flybase.org/reports/FBgn0260748 protein_coding_gene - - - "anon-15Db, CG5004" "IPR001849:Pleckstrin homology domain, IPR008984:SMAD/FHA domain, IPR011993:PH domain-like" CG5004 11-Aug-17 DroID_v2017_08 "Drer\phldb2b, Drer\phldb1a, Drer\phldb1b, Drer\phldb2a" - - "Xtro\phldb3, Xtro\phldb1" "Mmus\Phldb3, Mmus\Phldb1, Mmus\Phldb2" "Hsap\PHLDB3, Hsap\PHLDB2, Hsap\PHLDB1, Hsap\PLCXD2" FBgn0036300 Pmm2 Phosphomannomutase type 2 http://flybase.org/reports/FBgn0036300 protein_coding_gene phosphomannomutase activity ; GO:0004615 | inferred from biological aspect of ancestor with PANTHER:PTN000049281 GDP-mannose biosynthetic process ; GO:0009298 | inferred from electronic annotation with InterPro:IPR005002 mannose metabolic process ; GO:0006013 | inferred from biological aspect of ancestor with PANTHER:PTN000049281 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype protein N-linked glycosylation ; GO:0006487 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype protein targeting to ER ; GO:0045047 | inferred from biological aspect of ancestor with PANTHER:PTN000049281 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000049281 "CG10688, 33589256, Pmm2, pmm2" "IPR005002:Phosphomannomutase, IPR006379:HAD-superfamily hydrolase, subfamily IIB, IPR023214:HAD-like domain" CG10688 11-Aug-17 DroID_v2017_08 "Drer\LOC100007686, Drer\pmm2" Scer\SEC53 Cele\F52B11.2 "Xtro\pmm2, Xtro\pmm1" "Mmus\Pmm2, Mmus\Pmm1" "Hsap\PMM1, Hsap\PMM2" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC09780 K 0.119947883 0.29477912 0.218179312 0.0659971 0.748016143 2.721494619 FBgn0029823 CG3011 - http://flybase.org/reports/FBgn0029823 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR019798 glycine hydroxymethyltransferase activity ; GO:0004372 | inferred from sequence or structural similarity with UniProtKB:P34897 glycine metabolic process ; GO:0006544 | inferred from electronic annotation with InterPro:IPR019798 behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype L-serine biosynthetic process ; GO:0006564 | inferred from sequence or structural similarity with UniProtKB:P34897 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P34897 "144561_at, anon-WO03040301.100, CG3011, Shmt2" "IPR001085:Serine hydroxymethyltransferase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR019798:Serine hydroxymethyltransferase, pyridoxal phosphate binding site, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG3011 11-Aug-17 DroID_v2017_08 "Drer\shmt1, Drer\shmt2" "Scer\SHM2, Scer\SHM1" Cele\mel-32 "Xtro\shmt2, Xtro\shmt1" "Mmus\Shmt2, Mmus\Shmt1" "Hsap\SHMT2, Hsap\SHMT1" "viable,visible,hyperactive,conditional,chemical resistant" trichogen cell FBgn0263600 DNApol-delta DNA-polymerase-delta http://flybase.org/reports/FBgn0263600 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006134 nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR006134, InterPro:IPR006172, InterPro:IPR017964 DNA-directed DNA polymerase activity ; GO:0003887 | non-traceable author statement 3'-5'-exodeoxyribonuclease activity ; GO:0008296 | inferred from direct assay DNA-directed DNA polymerase activity ; GO:0003887 | inferred from direct assay" "neurogenesis ; GO:0022008 | inferred from mutant phenotype base-excision repair, gap-filling ; GO:0006287 | inferred from biological aspect of ancestor with PANTHER:PTN000035478 DNA replication proofreading ; GO:0045004 | inferred from biological aspect of ancestor with PANTHER:PTN000035478 nucleotide-excision repair, DNA gap filling ; GO:0006297 | inferred from biological aspect of ancestor with PANTHER:PTN000035478 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype" microtubule associated complex ; GO:0005875 | inferred from direct assay delta DNA polymerase complex ; GO:0043625 | inferred from direct assay "dnapol delta, DNApol-delta, l(3)72Ac, CG5949, CAA61369, Dm Poldelta, DNA Pol Delta, 5949, Poldelta, DNA pol delta" "IPR025687:C4-type zinc-finger of DNA polymerase delta, IPR023211:DNA polymerase, palm domain, IPR017964:DNA-directed DNA polymerase, family B, conserved site, IPR006133:DNA-directed DNA polymerase, family B, exonuclease domain, IPR006134:DNA-directed DNA polymerase, family B, multifunctional domain, IPR006172:DNA-directed DNA polymerase, family B, IPR012337:Ribonuclease H-like domain" CG5949 11-Aug-17 DroID_v2017_08 "Drer\pold1, Drer\rev3l" "Scer\REV3, Scer\POL3" Cele\F10C2.4 "Xtro\rev3l, Xtro\pold1" "Mmus\Rev3l, Mmus\Pold1" "Hsap\POLD1, Hsap\REV3L" FBgn0030893 RhoGAP16F Rho GTPase activating protein at 16F http://flybase.org/reports/FBgn0030893 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with HGNC:21030 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:21030 imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available "CG7122, RhoGAP16F" "IPR000198:Rho GTPase-activating protein domain, IPR008936:Rho GTPase activation protein" CG7122 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-253h3.1, Drer\arhgap27, Drer\arhgap9, Drer\arhgap22, Drer\arhgap12a, Drer\arhgap27l, Drer\arhgap15, Drer\arhgap12b" Scer\RGD1 Cele\tag-325 Xtro\arhgap27 "Mmus\Arhgap15, Mmus\Arhgap27, Mmus\Arhgap12, Mmus\Arhgap9" "Hsap\ARHGAP27, Hsap\ARHGAP12, Hsap\ARHGAP15, Hsap\ABR, Hsap\ARHGAP9" viable FBgn0040098 lectin-29Ca lectin-29Ca http://flybase.org/reports/FBgn0040098 protein_coding_gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG17799, Acp29AB-I, AC004423a, AC 004423A, lectin-29Ca, Lectin-29Ca" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG17799 11-Aug-17 DroID_v2017_08 "Drer\hbl1, Drer\acana, Drer\colec11, Drer\hbl2, Drer\hbl4, Drer\hbl3" - "Cele\clec-146, Cele\clec-149, Cele\clec-49, Cele\clec-50, Cele\clec-145" - "Mmus\Clec3b, Mmus\Klri1, Mmus\Colec11, Mmus\Mbl1, Mmus\Clec4g, Mmus\Clec3a, Mmus\Colec10, Mmus\Sftpd, Mmus\Klri2, Mmus\Clec11a, Mmus\Asgr2" "Hsap\COLEC11, Hsap\CLEC3B, Hsap\CLEC17A, Hsap\CD209, Hsap\CLEC3A, Hsap\SFTPA2, Hsap\COLEC10, Hsap\SFTPD, Hsap\MBL2, Hsap\SFTPA1, Hsap\CLEC4A, Hsap\FCER2" FBgn0263832 Rcd5 Reduction in Cnn dots 5 http://flybase.org/reports/FBgn0263832 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with nsl1 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs centriole replication ; GO:0007099 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay NSL complex ; GO:0044545 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay "MCRS2, CG1135, l(3)r0166, l(3)rG166, MCRS1, dMCRS2, p78, dMCRS1, Rcd5" "IPR000253:Forkhead-associated (FHA) domain, IPR008984:SMAD/FHA domain, IPR025999:Microspherule protein, N-terminal domain" CG1135 11-Aug-17 DroID_v2017_08 Drer\mcrs1 - Cele\mcrs-1 Xtro\mcrs1 Mmus\Mcrs1 Hsap\MCRS1 "lethal,recessive,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage" DRSC08180 E -0.420515883 0.003007192 -0.057181843 -4.635823709 0.797343734 -1.047486802 FBgn0035060 Eps-15 Epidermal growth factor receptor pathway substrate clone 15 http://flybase.org/reports/FBgn0035060 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype receptor-mediated endocytosis ; GO:0006898 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay synaptic vesicle ; GO:0008021 | colocalizes_with inferred from direct assay "eps15, Eps15, i31, CG16932, eps-15, EPS-15, anon-WO0118547.85, Eps-15, EH1, EPS15" "IPR018247:EF-Hand 1, calcium-binding site, IPR000261:EH domain, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG16932 11-Aug-17 DroID_v2017_08 "Drer\eps15, Drer\eps15l1b, Drer\eps15l1a, Drer\si:ch73-140j24.4, Drer\synrg" "Scer\EDE1, Scer\END3, Scer\PAN1, Scer\SLA1, Scer\TAX4, Scer\TPM1, Scer\IRS4" "Cele\reps-1, Cele\ehs-1" "Xtro\eps15, Xtro\eps15l1" "Mmus\Eps15l1, Mmus\Eps15" "Hsap\EPS15L1, Hsap\EPS15" "lethal,neuroanatomy defective,neurophysiology defective,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die,fertile,lethal - all die before end of pupal stage,some die during pupal stage,recessive,viable,lethal - all die before end of larval stage,some die during third instar larval stage" "glial cell,eye disc,embryonic/larval neuromuscular junction,bouton,supernumerary,macrochaeta,socket,eo sensory structure" FBgn0041194 Prat2 Phosphoribosylamidotransferase 2 http://flybase.org/reports/FBgn0041194 protein_coding_gene amidophosphoribosyltransferase activity ; GO:0004044 | inferred from electronic annotation with InterPro:IPR005854 purine nucleobase biosynthetic process ; GO:0009113 | inferred from electronic annotation with InterPro:IPR005854 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000836 - "CG10078, Prat2, DmPrat2" "IPR000836:Phosphoribosyltransferase domain, IPR005854:Amidophosphoribosyltransferase, IPR017932:Glutamine amidotransferase type 2 domain, IPR029055:Nucleophile aminohydrolases, N-terminal, IPR029057:Phosphoribosyltransferase-like" CG10078 11-Aug-17 DroID_v2017_08 Drer\ppat "Scer\YMR084W, Scer\ADE4" Cele\ppat-1 Xtro\ppat Mmus\Ppat Hsap\PPAT "female fertile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,partially,some die during pupal stage,viable" "head | P-stage,leg | P-stage,abdomen | P-stage,cephalopharyngeal skeleton | P-stage" FBgn0037008 mTerf3 mitochondrial transcription termination factor 3 http://flybase.org/reports/FBgn0037008 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from electronic annotation with InterPro:IPR003690 single-stranded RNA binding ; GO:0003727 | inferred from biological aspect of ancestor with PANTHER:PTN000317011 small ribosomal subunit rRNA binding ; GO:0070181 | inferred from direct assay mitochondrial translation ; GO:0032543 | inferred from mutant phenotype positive regulation of mitochondrial translation ; GO:0070131 | inferred from mutant phenotype developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN000317011 transcription from mitochondrial promoter ; GO:0006390 | NOT inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from biological aspect of ancestor with PANTHER:PTN000317011 regulation of cell cycle ; GO:0051726 | inferred from direct assay mitochondrial ribosome assembly ; GO:0061668 | inferred from mutant phenotype regulation of transcription from mitochondrial promoter ; GO:1903108 | inferred from mutant phenotype mitochondrial DNA replication ; GO:0006264 | NOT inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "mTerf3, D-MTERF3, CG5047, MTERF3, DmMterf3, Mterf3, DmMTERF3" "IPR003690:Transcription termination factor, mitochondrial/chloroplastic" CG5047 11-Aug-17 DroID_v2017_08 "Drer\mterf2, Drer\mterf3, Drer\mterf1, Drer\kcnj1a.2, Drer\si:dkeyp-94h10.5" - "Cele\C50F4.12, Cele\K11D2.5" "Xtro\mterf3, Xtro\mterf2, Xtro\mterf1" "Mmus\Mterf2, Mmus\Mterf1a, Mmus\Mterf3, Mmus\Mterf1b" "Hsap\MTERF1, Hsap\MTERF2, Hsap\MTERF3" viable FBgn0260399 gwl greatwall http://flybase.org/reports/FBgn0260399 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290 protein binding ; GO:0005515 | inferred from physical interaction with polo protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay 14-3-3 protein binding ; GO:0071889 | inferred from physical interaction with 14-3-3ζ inferred from physical interaction with 14-3-3ε" "regulation of mitotic centrosome separation ; GO:0046602 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype negative regulation of phosphoprotein phosphatase activity ; GO:0032515 | inferred from genetic interaction with polo, mts inferred from genetic interaction with polo, tws intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 chromosome condensation ; GO:0030261 | inferred from mutant phenotype regulation of meiotic nuclear division ; GO:0040020 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype inferred from genetic interaction with polo protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity female meiotic division ; GO:0007143 | inferred from mutant phenotype female meiosis I ; GO:0007144 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement" nuclear envelope ; GO:0005635 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "gwl, CG7719, Pk91C, EP0515, CG7719-related, CT23435, 1J, Pk?2, anon-WO2004063362.73, scant, Gwl" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG7719 11-Aug-17 DroID_v2017_08 "Drer\rock2b, Drer\mastl" "Scer\FPK1, Scer\RIM15, Scer\KIN82" - "Xtro\cdc42bpb, Xtro\mastl" Mmus\Mastl Hsap\MASTL FBgn0051368 CG31368 - http://flybase.org/reports/FBgn0051368 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:29513 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from electronic annotation with InterPro:IPR026300 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay Prp19 complex ; GO:0000974 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG31368, CG14729, CG14730" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026300:CWF11 family, IPR032174:Intron-binding protein aquarius, N-terminal" CG31368 11-Aug-17 DroID_v2017_08 "Drer\aqr, Drer\setx" "Scer\SEN1, Scer\HCS1" Cele\emb-4 Xtro\aqr Mmus\Aqr "Hsap\AQR, Hsap\SETX" FBgn0051715 CG31715 - http://flybase.org/reports/FBgn0051715 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE44624, CG31715" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG31715 11-Aug-17 DroID_v2017_08 "Drer\mtpn, Drer\zgc:113279" "Scer\YGL242C, Scer\SPT23, Scer\MGA2, Scer\YCR051W" "Cele\C43H6.3, Cele\F22G12.4" Xtro\mtpn Mmus\Mtpn "Hsap\ANKRD7, Hsap\MTPN, Hsap\ASB12, Hsap\LUZP6" viable FBgn0263220 Hk Hyperkinetic http://flybase.org/reports/FBgn0263220 protein_coding_gene potassium channel regulator activity ; GO:0015459 | inferred from mutant phenotype voltage-gated potassium channel activity ; GO:0005249 | inferred from sequence or structural similarity voltage-gated potassium channel activity ; GO:0005249 | contributes_to inferred from direct assay "flight behavior ; GO:0007629 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from sequence or structural similarity potassium ion transport ; GO:0006813 | inferred from direct assay protein oligomerization ; GO:0051259 | inferred from physical interaction with eag positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype circadian sleep/wake cycle, sleep ; GO:0050802 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR005983 voltage-gated potassium channel complex ; GO:0008076 | inferred from physical interaction with eag voltage-gated potassium channel complex ; GO:0008076 | inferred from physical interaction with Sh voltage-gated potassium channel complex ; GO:0008076 | inferred from sequence or structural similarity "CG43388, Hk, CG32688, CG17779, CG2287, CG34319, lincRNA.975, Hyperkinetic, Dm_X:51771, hk" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR005399:Potassium channel, voltage-dependent, beta subunit, KCNAB-related, IPR005983:Potassium channel, voltage-dependent, beta subunit, KCNAB, IPR023210:NADP-dependent oxidoreductase domain" CG43388 11-Aug-17 DroID_v2017_08 "Drer\kcnab2a, Drer\kcnab2b, Drer\kcnab1b, Drer\LOC100334158, Drer\kcnab1a" "Scer\AAD10, Scer\AAD14, Scer\YPL088W, Scer\YPR127W, Scer\AAD4, Scer\AAD3, Scer\ARA2, Scer\AAD15" "Cele\C07D8.6, Cele\F53F1.2, Cele\mec-14, Cele\F53F1.3" "Xtro\kcnab2, Xtro\kcnab1, Xtro\kcnab3" "Mmus\Kcnab2, Mmus\Kcnab3, Mmus\Kcnab1" "Hsap\KCNAB3, Hsap\KCNAB1, Hsap\KCNAB2" FBgn0053208 Mical Molecule interacting with CasL http://flybase.org/reports/FBgn0053208 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 actin binding ; GO:0003779 | inferred from direct assay NADPH:sulfur oxidoreductase activity ; GO:0043914 | inferred from direct assay oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen ; GO:0016709 | inferred from direct assay oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen ; GO:0016709 | inferred from mutant phenotype FAD binding ; GO:0071949 | inferred from direct assay" actin modification ; GO:0030047 | inferred from direct assay axon guidance ; GO:0007411 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype synapse assembly involved in innervation ; GO:0060386 | inferred from mutant phenotype oxidation-reduction process ; GO:0055114 | inferred from direct assay regulation of neuron remodeling ; GO:1904799 | inferred from mutant phenotype actin filament depolymerization ; GO:0030042 | inferred from direct assay sarcomere organization ; GO:0045214 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype NADPH oxidation ; GO:0070995 | inferred from direct assay actin filament depolymerization ; GO:0030042 | inferred from direct assay inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype inferred from genetic interaction with Sox14 sulfur oxidation ; GO:0019417 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype inferred from genetic interaction with Sox14 neuron remodeling ; GO:0016322 | inferred from mutant phenotype cytosol ; GO:0005829 | non-traceable author statement terminal bouton ; GO:0043195 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG33190, CG33186, CG18668, CG18667, CG18484, CG11687, CG11685, CG33208, Mical, MICAL, mical, milch, mdcds_49226" "IPR001715:Calponin homology domain, IPR001781:Zinc finger, LIM-type, IPR022735:Domain of unknown function DUF3585, IPR023753:FAD/NAD(P)-binding domain" CG33208 11-Aug-17 DroID_v2017_08 "Drer\mical1, Drer\mical3a, Drer\mical2b, Drer\mical3b, Drer\mical2a" - - "Xtro\mical3, Xtro\mical2" "Mmus\Mical2, Mmus\Dsp, Mmus\Micalcl, Mmus\Mical1, Mmus\Mical3" "Hsap\MICAL1, Hsap\MICAL3, Hsap\MICAL2, Hsap\DSP, Hsap\MICALCL" "visible,lethal,neuroanatomy defective,flight defective,viable,fertile,flightless,somatic clone" "macrochaeta,filamentous actinB11-98,embryonic/larval somatic muscle | third instar larval stage,growth coneeve.RN2,intersegmental nerve,segmental nerve,embryonic/larval neuromuscular junction,bouton,myofibrilswp2MICAL),indirect flight muscle,embryonic/larval muscle system,sarcomere,embryonic/larval somatic muscle,filamentous actin | third instar larval stage,synapse,filamentous actin,abdominal segmental nerve,intersegmental nerve branch ISNb of A1-7,flight muscle,abdominal intersegmental nerve,presumptive embryonic/larval central nervous system,ventral nerve cord,sarcomereMef2.PR,dendriteppk.1.9,dorsal multidendritic neuron ddaC,trichogen cell,dendrite221,somatic clone,dendrite,dendriteswp2MICAL)" DRSC15365 I 1.115290316 1.678497371 0.864773841 0.140537224 0.87533845 0.353451044 FBgn0011802 Gem3 Gemin3 http://flybase.org/reports/FBgn0011802 FBgn0027895 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype ribonucleoprotein complex assembly ; GO:0022618 | inferred from mutant phenotype spliceosomal snRNP assembly ; GO:0000387 | inferred from sequence or structural similarity with UniProtKB:Q9UHI6 adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype Cajal body ; GO:0015030 | inferred from direct assay cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay SMN complex ; GO:0032797 | inferred from mutant phenotype "DHH1, DmRH22, l(3)rL562, BcDNA.LD05563, CG6539, BcDNA:LD05563, Gem3, dGem3, Dhh1" "IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG6539 11-Aug-17 DroID_v2017_08 "Drer\ddx20, Drer\ddx43" Scer\DHH1 Cele\mel-46 Xtro\ddx20 "Mmus\Ddx43, Mmus\Ddx20" "Hsap\DDX20, Hsap\DDX53, Hsap\DDX43" "partially lethal - majority die,some die during pupal stage,lethal,viable,visible,gravitaxis defective,progressive,flightless,short lived,heat sensitive,flight defective,partially lethal - majority live,small body,locomotor behavior defective,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,developmental rate defective,partially" "trichogen cell,anterior pupal spiracle,puparium,embryonic/larval neuromuscular junction,embryonic/larval neuromuscular junction | larval stage,head | pupal stage,wing | pupal stage,leg | pupal stage,indirect flight muscle" FBgn0039627 CG11837 - http://flybase.org/reports/FBgn0039627 protein_coding_gene "rRNA (adenine-N6,N6-)-dimethyltransferase activity ; GO:0000179 | inferred from biological aspect of ancestor with PANTHER:PTN000197843" "rRNA modification ; GO:0000154 | inferred from electronic annotation with InterPro:IPR020596, InterPro:IPR020598 sleep ; GO:0030431 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype" mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000197847 "FBgn0039627, CG11837, Dim1" "IPR001737:Ribosomal RNA adenine methyltransferase KsgA/Erm, IPR011530:Ribosomal RNA adenine dimethylase, IPR020596:Ribosomal RNA adenine methylase transferase, conserved site, IPR020598:Ribosomal RNA adenine methylase transferase, N-terminal, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG11837 11-Aug-17 DroID_v2017_08 "Drer\tfb1m, Drer\dimt1l, Drer\tfb2m" "Scer\MTF1, Scer\DIM1" "Cele\E02H1.1, Cele\tfbm-1" Xtro\dimt1 "Mmus\Tfb1m, Mmus\Dimt1, Mmus\Tfb2m" "Hsap\TFB1M, Hsap\DIMT1, Hsap\TFB2M" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell" FBgn0040226 en::Su(H) en::Su(H) http://flybase.org/reports/FBgn0040226 engineered_fusion_gene - - - en::Su(H) - - 11-Aug-17 DroID_v2017_08 - - - - - - "planar polarity defective,somatic clone" "ommatidium,somatic clone,photoreceptor cell R7,lens,rhabdomere,eye photoreceptor cell,supernumerary" FBgn0039008 CG6972 - http://flybase.org/reports/FBgn0039008 protein_coding_gene - muscle system process ; GO:0003012 | inferred from expression pattern inferred from genetic interaction with Mhc - CG6972 "IPR011989:Armadillo-like helical, IPR008580:PPPDE putative peptidase domain" CG6972 11-Aug-17 DroID_v2017_08 "Drer\desi1b, Drer\desi1a" - - - Mmus\Desi1 Hsap\DESI1 "body color defective,partially lethal - majority die,some die during pupal stage,viable" mesothoracic tergum DRSC16159 K 0.519120971 0.355086143 0.935898595 0.031468977 1.435592535 1.534828888 FBgn0014236 l(2)31Es lethal (2) 31Es http://flybase.org/reports/FBgn0014236 - gene - - - l(2)31Es - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0026086 Adar Adenosine deaminase acting on RNA http://flybase.org/reports/FBgn0026086 "FBgn0022736, FBgn0041575" protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002466 double-stranded RNA adenosine deaminase activity ; GO:0003726 | inferred from direct assay double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR002466 RNA modification ; GO:0009451 | inferred from direct assay mRNA modification ; GO:0016556 | inferred from mutant phenotype adenosine to inosine editing ; GO:0006382 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype regulation of gene silencing by miRNA ; GO:0060964 | inferred from mutant phenotype adenosine to inosine editing ; GO:0006382 | inferred from direct assay regulation of membrane potential ; GO:0042391 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | traceable author statement male courtship behavior ; GO:0008049 | inferred from mutant phenotype adult behavior ; GO:0030534 | inferred from mutant phenotype mRNA modification ; GO:0016556 | inferred from direct assay regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype mRNA modification ; GO:0016556 | traceable author statement regulation of circadian rhythm ; GO:0042752 | inferred from direct assay intracellular ; GO:0005622 | inferred by curator from GO:0003726 "ADAR1, dADAR, dAdar, ADAR, hypnos-2, EG:BACN35H14.1, CG12598, cg12598, Adar, adar, adr, dadar" "IPR002466:Adenosine deaminase/editase, IPR014720:Double-stranded RNA-binding domain" CG12598 11-Aug-17 DroID_v2017_08 "Drer\adar, Drer\adad2, Drer\ilf3a, Drer\adad1, Drer\adarb1a, Drer\adarb1b, Drer\ilf3b, Drer\adat1, Drer\adarb2, Drer\strbp" Scer\TAD1 "Cele\adr-1, Cele\R11H6.5, Cele\adr-2, Cele\D2005.1" "Xtro\adarb1, Xtro\adat1, Xtro\adarb2, Xtro\adar, Xtro\adad1" "Mmus\Strbp, Mmus\Adarb1, Mmus\Adad1, Mmus\Adad2, Mmus\Adat1, Mmus\Ilf3, Mmus\Adarb2, Mmus\Adar" "Hsap\ILF3, Hsap\ADAT1, Hsap\STRBP, Hsap\ADARB2, Hsap\ADARB1, Hsap\ADAD2, Hsap\ADAD1, Hsap\ADAR" "locomotor rhythm defective,courtship behavior defective,gravitaxis defective,wild-type,partially lethal - majority die,paralytic,temperature conditional,viable,song defective,lethal,conditional,recessive,behavior defective,heat sensitive,male,grooming behavior defective,locomotor behavior defective,flight defective,uncoordinated,neurophysiology defective,dominant,stress response defective,heat stress response defective,short lived,neuroanatomy defective,partially lethal - majority live,visible,some die during pupal stage" "wing,adult central nervous system,medulla,lobula,lamina,type I bouton,synapse,neuromuscular junction,photoreceptor cell,adult brain,optic lobe,retina,heat sensitive,trichogen cell,mesothoracic tergum" DRSC17725 K 0.144107025 0.28952365 -0.587584984 0.000969972 3.060108026 1.808294074 FBgn0005221 l(3)ET16 lethal Elaine Tasaka 16 http://flybase.org/reports/FBgn0005221 - gene - - - l(3)ET16 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,heat sensitive,visible" wing FBgn0003085 pig pigmy http://flybase.org/reports/FBgn0003085 - gene - - - "pg, pig" - - 11-Aug-17 DroID_v2017_08 - - - - - - "small body,viable,reduced,body color defective" FBgn0033693 CG13175 - http://flybase.org/reports/FBgn0033693 protein_coding_gene molecular_function ; GO:0003674 | no biological data available ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN002003828 cellular_component ; GO:0005575 | no biological data available "CG33154, CG13175" "IPR019191:Essential protein Yae1, N-terminal" CG13175 11-Aug-17 DroID_v2017_08 Drer\oraov1 Scer\LTO1 - - Mmus\Oraov1 Hsap\ORAOV1 FBgn0026576 CG5991 - http://flybase.org/reports/FBgn0026576 FBgn0039143 protein_coding_gene "phosphatidylserine decarboxylase activity ; GO:0004609 | inferred from electronic annotation with InterPro:IPR003817, InterPro:IPR033177, InterPro:IPR033661" phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR003817 mitochondrion ; GO:0005739 | inferred from electronic annotation with InterPro:IPR033661 "LD21713, BEST:LD21713, CG5991, Psd" "IPR003817:Phosphatidylserine decarboxylase-related, IPR033177:Phosphatidylserine decarboxylase, IPR033661:Phosphatidylserine decarboxylase, eukaryotic type 1" CG5991 11-Aug-17 DroID_v2017_08 Drer\pisd "Scer\PSD1, Scer\PSD2" Cele\psd-1 "Xtro\pisd, Xtro\pisd" Mmus\Pisd Hsap\PISD "partially lethal - majority die,visible,lethal,viable" "eye,tarsal segment" DRSC15935 I 0.297431888 3.844682968 0.101835545 0.077081268 -0.927764673 0.528120355 FBgn0025391 Scgdelta Sarcoglycan delta http://flybase.org/reports/FBgn0025391 FBgn0047354 protein_coding_gene structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC:10807 inferred from sequence or structural similarity with HGNC:10809 membrane organization ; GO:0061024 | inferred from biological aspect of ancestor with PANTHER:PTN000986439 cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity mesoderm development ; GO:0007498 | inferred from expression pattern heart contraction ; GO:0060047 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from biological aspect of ancestor with PANTHER:PTN000986439 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006875 sarcoglycan complex ; GO:0016012 | inferred from biological aspect of ancestor with PANTHER:PTN000986439 costamere ; GO:0043034 | inferred from direct assay sarcolemma ; GO:0042383 | inferred from biological aspect of ancestor with PANTHER:PTN000986439 sarcoglycan complex ; GO:0016012 | inferred from sequence or structural similarity sarcoglycan complex ; GO:0016012 | inferred from sequence or structural similarity with HGNC:10807 inferred from sequence or structural similarity with HGNC:10809 "CG14808, EG:4F1.1, CT34621, DmSCG-gammadelta, Scgdelta, GH21860, BEST:GH21860, Sgcd" IPR006875:Sarcoglycan complex subunit protein CG14808 11-Aug-17 DroID_v2017_08 "Drer\sgcg, Drer\sgcd, Drer\sgcz" - Cele\sgn-1 "Xtro\sgcd, Xtro\sgcg, Xtro\sgcz" "Mmus\Sgcz, Mmus\Sgcg, Mmus\Sgcd, Mmus\Sgcb" "Hsap\SGCG, Hsap\SGCD, Hsap\SGCZ, Hsap\SGCB" "viable,short lived,gravitaxis defective" "adult heart,dorsal medial muscle,M band,sarcomere,indirect flight muscle" FBgn0046692 Stlk Ste20-like kinase http://flybase.org/reports/FBgn0046692 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein phosphorylation ; GO:0006468 | NOT inferred from key residues cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:30172 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:30172 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 "CG40293, LD05623, BcDNA:LD05623, Stlk, stlk" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain" CG40293 11-Aug-17 DroID_v2017_08 "Drer\oxsr1a, Drer\wu:fj77h11, Drer\oxsr1b, Drer\strada, Drer\stk39" Scer\STE20 Cele\strd-1 "Xtro\stk39, Xtro\stradb, Xtro\strada" "Mmus\Oxsr1, Mmus\Stradb, Mmus\Strada, Mmus\Stk39" "Hsap\STK39, Hsap\STRADA, Hsap\OXSR1, Hsap\STRADB" FBgn0014009 Rab2 Rab2 http://flybase.org/reports/FBgn0014009 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with Gmap, Golgin245, GCC88, GCC185 protein binding ; GO:0005515 | inferred from physical interaction with BicD inferred from physical interaction with Golgin104 inferred from physical interaction with CG9590 inferred from physical interaction with Vps39 inferred from physical interaction with CG32485 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 plasma membrane ; GO:0005886 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 "Rab2, DmRab2, rab2, CG3269, Drab2, DRab2, DRAB2, O18333" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3269 11-Aug-17 DroID_v2017_08 "Drer\rab2a, Drer\rab4a, Drer\rab14l, Drer\rab4b, Drer\rab14, Drer\dnajc27" "Scer\YPT31, Scer\YPT32, Scer\YPT11" "Cele\F11A5.4, Cele\F11A5.3, Cele\unc-108" "Xtro\dnajc27, Xtro\rab4b, Xtro\rab2a, Xtro\rab2b, Xtro\rab14" "Mmus\Rab2b, Mmus\Dnajc27, Mmus\Rab14, Mmus\Rab2a, Mmus\Rab4b, Mmus\Rab4a" "Hsap\RAB4A, Hsap\RAB4B, Hsap\RAB2B, Hsap\RAB14, Hsap\DNAJC27, Hsap\RAB2A" " embryonic stage | stage 14-15 , embryonic stage -- adult stage , embryonic stage " " embryonic peripheral nervous system

, embryonic central nervous system

" "lethal,recessive,viable,immune response defective" "phagocytic vesicleHml.‘î,hemocyte | adult stage" FBgn0051954 CG31954 - http://flybase.org/reports/FBgn0051954 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP107, CG3229, CG31954" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG31954 11-Aug-17 DroID_v2017_08 "Drer\prss59.2, Drer\si:ch211-165b19.9, Drer\LOC103908930, Drer\prss12, Drer\gzm3" - "Cele\try-1, Cele\rab-11.1, Cele\svh-1" "Xtro\gzma, Xtro\try10, Xtro\gzmak, Xtro\LOC100498532" "Mmus\Gzmd, Mmus\Prss3, Mmus\Try4, Mmus\Klk4, Mmus\Gzma, Mmus\Gzmk, Mmus\1700074P13Rik, Mmus\Try5, Mmus\2210010C04Rik, Mmus\Prss58, Mmus\Tpsg1, Mmus\Gzme, Mmus\Prss37, Mmus\Try10, Mmus\Prss1, Mmus\Gm5771, Mmus\Gm2663, Mmus\Prss2, Mmus\Gzmg, Mmus\Klk1b16, Mmus\Tmprss5" "Hsap\TMPRSS5, Hsap\GZMK, Hsap\PRSS3, Hsap\PRSS1, Hsap\PRSS2, Hsap\PRSS58, Hsap\PRSS37, Hsap\TPSG1" viable FBgn0034519 CG18065 - http://flybase.org/reports/FBgn0034519 protein_coding_gene - - - "CG33008, CG18065" IPR032143:BLOC-1-related complex subunit 7 CG18065 11-Aug-17 DroID_v2017_08 Drer\borcs7 - Cele\blos-8 Xtro\borcs7 Mmus\Borcs7 Hsap\BORCS7 DRSC06707 I -1.492973811 -1.901626673 -0.293269257 0.064279524 -0.943643027 -0.242055408 FBgn0029939 CG9650 - http://flybase.org/reports/FBgn0029939 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000579295" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 negative regulation of peptide hormone secretion ; GO:0090278 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 neurogenesis ; GO:0022008 | inferred from biological aspect of ancestor with PANTHER:PTN001905569" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 cytosol ; GO:0005829 | inferred from direct assay CG9650 "IPR013087:Zinc finger C2H2-type, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9650 11-Aug-17 DroID_v2017_08 "Drer\im:7142702, Drer\znf296, Drer\bcl11ba, Drer\sall4, Drer\si:ch211-266d19.4, Drer\bcl11aa, Drer\znf983, Drer\bcl11ab" - Cele\bcl-11 "Xtro\bcl11a, Xtro\bcl11b" "Mmus\Zfp35, Mmus\Zfp677, Mmus\Zfp51, Mmus\Zfp189, Mmus\Zfp296, Mmus\Zfp442, Mmus\Zfp708, Mmus\Bcl11b, Mmus\Zscan2, Mmus\Bcl11a, Mmus\Zfp658, Mmus\Zfp560, Mmus\Zfp948, Mmus\Zfp930" "Hsap\ZNF226, Hsap\ZNF234, Hsap\ZNF227, Hsap\ZNF836, Hsap\ZNF85, Hsap\ZNF287, Hsap\BCL11A, Hsap\ZNF93, Hsap\ZNF700, Hsap\ZNF708, Hsap\ZNF189, Hsap\ZNF616, Hsap\ZFP62, Hsap\ZNF675, Hsap\ZNF678, Hsap\ZNF296, Hsap\ZKSCAN7, Hsap\ZNF845, Hsap\ZNF184, Hsap\ZNF429, Hsap\ZNF235, Hsap\RBAK-RBAKDN, Hsap\ZNF729, Hsap\ZNF721, Hsap\ZNF92, Hsap\ZNF16, Hsap\BCL11B, Hsap\ZNF528, Hsap\ZSCAN2, Hsap\ZNF43, Hsap\ZNF45, Hsap\ZNF600" "lethal,visible,recessive,viable,partially lethal - majority die" "ventral nerve cord commissure,longitudinal connective,eye,ommatidium,interommatidial bristle" FBgn0037713 CG16790 - http://flybase.org/reports/FBgn0037713 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8INK6 3'-5'-exoribonuclease activity ; GO:0000175 | inferred from biological aspect of ancestor with PANTHER:PTN000338265 U6 snRNA 3'-end processing ; GO:0034477 | inferred from biological aspect of ancestor with PANTHER:PTN000338265 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000338265 CG16790 "IPR009097:Cyclic phosphodiesterase, IPR027521:U6 snRNA phosphodiesterase Usb1" CG16790 11-Aug-17 DroID_v2017_08 Drer\usb1 Scer\USB1 - Xtro\usb1 Mmus\Usb1 Hsap\USB1 viable FBgn0032054 Uba4 Ubiquitin activating enzyme 4 http://flybase.org/reports/FBgn0032054 protein_coding_gene thiosulfate sulfurtransferase activity ; GO:0004792 | inferred from sequence or structural similarity with UniProtKB:O95396 thiosulfate sulfurtransferase activity ; GO:0004792 | inferred from sequence or structural similarity with HGNC:15765 UFM1 activating enzyme activity ; GO:0071566 | inferred from sequence or structural similarity with HGNC:15765 tRNA wobble position uridine thiolation ; GO:0002143 | inferred from electronic annotation with InterPro:IPR028885 protein urmylation ; GO:0032447 | inferred from mutant phenotype Mo-molybdopterin cofactor biosynthetic process ; GO:0006777 | inferred from sequence or structural similarity with UniProtKB:O95396 tRNA thio-modification ; GO:0034227 | inferred from sequence or structural similarity with HGNC:15765 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:O95396 molybdopterin synthase complex ; GO:0019008 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:15765 cytoplasm ; GO:0005737 | inferred from direct assay "CG13090, dMoaD, Uba4" "IPR000594:THIF-type NAD/FAD binding fold, IPR001763:Rhodanese-like domain, IPR028885:Adenylyltransferase and sulfurtransferase MOCS3/Uba4" CG13090 11-Aug-17 DroID_v2017_08 Drer\mocs3 Scer\UBA4 Cele\moc-3 Xtro\mocs3 Mmus\Mocs3 Hsap\MOCS3 viable FBgn0053864 His1:CG33864 His1:CG33864 http://flybase.org/reports/FBgn0053864 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33864, His1:CG33864" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33864 11-Aug-17 DroID_v2017_08 "Drer\zgc:110425, Drer\si:dkey-108k21.14, Drer\si:ch211-113a14.24, Drer\h1f0, Drer\si:ch73-36p18.1, Drer\h1m, Drer\si:dkey-261m9.12, Drer\si:dkey-108k21.21, Drer\zgc:110216, Drer\si:ch1073-159d7.7, Drer\zgc:153405, Drer\h1fx, Drer\si:dkey-108k21.10, Drer\histh1l, Drer\zgc:163061" Scer\HHO1 "Cele\hil-5, Cele\hil-4, Cele\hil-6, Cele\his-24, Cele\hil-2, Cele\hil-1, Cele\hil-3" - "Mmus\Hist1h1c, Mmus\Hist1h1e, Mmus\H1fnt, Mmus\Hist1h1t, Mmus\Hils1, Mmus\Hist1h1a, Mmus\H1fx, Mmus\H1foo, Mmus\Hist1h1b, Mmus\Hist1h1d" "Hsap\H1F0, Hsap\H1FOO, Hsap\HIST1H1C, Hsap\HIST1H1E, Hsap\HIST1H1A, Hsap\HIST1H1T, Hsap\HIST1H1D, Hsap\H1FNT, Hsap\H1FX, Hsap\HIST1H1B" FBgn0028875 nAChRalpha5 nicotinic Acetylcholine Receptor alpha5 http://flybase.org/reports/FBgn0028875 protein_coding_gene acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity acetylcholine-gated cation channel activity ; GO:0022848 | inferred from direct assay acetylcholine binding ; GO:0042166 | inferred from direct assay acetylcholine-gated cation channel activity ; GO:0022848 | contributes_to inferred from direct assay cation transport ; GO:0006812 | inferred from direct assay "postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394 integral component of membrane ; GO:0016021 | inferred from direct assay acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity acetylcholine-gated channel complex ; GO:0005892 | inferred from direct assay acetylcholine-gated channel complex ; GO:0005892 | inferred from physical interaction with nAChRα6, nAChRα7" "Dalpha5, nAChR, CT14633, BG:DS05899.4, BG:DS05899.5, CG4498, CG16878, CG32975, anon-WO02059370.44, nAcRalpha-34E, lincRNA.S1055, lincRNA.128, Nic 34E, daf, nAChRalpha-34E, nAChRalpha5, nAcRalpha-34e, da5" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG32975 11-Aug-17 DroID_v2017_08 "Drer\chrnb2b, Drer\chrnb3a, Drer\LOC101882451, Drer\si:ch73-380n15.2, Drer\chrnb3b, Drer\chrna10a, Drer\chrne, Drer\chrnd, Drer\LOC798522, Drer\chrnb1l, Drer\chrna4b, Drer\si:ch211-39a7.1, Drer\chrnb4, Drer\chrna2a, Drer\chrng, Drer\chrna9, Drer\chrna7, Drer\chrna1, Drer\chrnb2l, Drer\chrna2b, Drer\chrna3, Drer\chrnb1, Drer\chrna6" - "Cele\lgc-4, Cele\acr-7, Cele\acr-19, Cele\acr-12, Cele\acr-3, Cele\acr-14, Cele\acr-6, Cele\acr-21, Cele\eat-2, Cele\lev-1, Cele\W10G11.17, Cele\acr-16, Cele\acr-10, Cele\unc-63, Cele\acr-11, Cele\acr-2, Cele\acr-15, Cele\acr-25, Cele\acr-8, Cele\acr-9, Cele\unc-38" "Xtro\chrna5, Xtro\chrna1, Xtro\chrne, Xtro\chrna2, Xtro\chrnb2, Xtro\chrng, Xtro\chrna6, Xtro\chrnd, Xtro\chrnb3, Xtro\chrna9, Xtro\chrna1.2, Xtro\chrna7" "Mmus\Chrna10, Mmus\Chrnb1, Mmus\Chrna1, Mmus\Chrnb4, Mmus\Chrna6, Mmus\Chrna7, Mmus\Chrnd, Mmus\Chrna2, Mmus\Chrna4, Mmus\Chrna3, Mmus\Chrna5, Mmus\Chrna9, Mmus\Chrnb3, Mmus\Chrne, Mmus\Chrng" "Hsap\CHRNB3, Hsap\CHRNE, Hsap\CHRNB2, Hsap\CHRNB1, Hsap\CHRFAM7A, Hsap\CHRNA6, Hsap\CHRNA5, Hsap\CHRNA7, Hsap\CHRNA1, Hsap\CHRNA3, Hsap\CHRNG, Hsap\CHRND, Hsap\CHRNA9, Hsap\CHRNA4, Hsap\CHRNA10, Hsap\CHRNB4, Hsap\CHRNA2" "lethal,viable" FBgn0022224 ubl ubiquitin like http://flybase.org/reports/FBgn0022224 FBgn0033105 protein_coding_gene protein tag ; GO:0031386 | inferred from biological aspect of ancestor with PANTHER:PTN000315756 "positive regulation of MyD88-dependent toll-like receptor signaling pathway ; GO:0034126 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000315756 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular protein modification process ; GO:0006464 | inferred from biological aspect of ancestor with PANTHER:PTN000315756" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000315756 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9BZL1 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000315756 "CG3450, l(2)k03203, mut182, dubl, ubl, Ubl" "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG3450 11-Aug-17 DroID_v2017_08 Drer\zgc:66388 Scer\HUB1 Cele\ubl-5 Xtro\ubl5 "Mmus\Ubl5, Mmus\Gm16381, Mmus\Gm2001" Hsap\UBL5 "lethal,recessive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0000039 nAChRalpha2 nicotinic Acetylcholine Receptor alpha2 http://flybase.org/reports/FBgn0000039 - protein_coding_gene acetylcholine-gated cation channel activity ; GO:0022848 | contributes_to inferred from direct assay acetylcholine-gated cation channel activity ; GO:0022848 | inferred from sequence or structural similarity acetylcholine receptor activity ; GO:0015464 | contributes_to inferred from direct assay "cation transport ; GO:0006812 | inferred from direct assay synaptic transmission, cholinergic ; GO:0007271 | inferred from expression pattern" postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394 acetylcholine-gated channel complex ; GO:0005892 | inferred from sequence or structural similarity acetylcholine-gated channel complex ; GO:0005892 | inferred from direct assay acetylcholine-gated channel complex ; GO:0005892 | inferred from physical interaction with nAChRα1 "CG6844, nAcRalpha-96Ab, Dalpha2, nAChR, SAD, Dalpha2/SAD, nAcr96Ab, nAcRs, sad, Da2, Acr96Ab, da2, alpha2, alpha[[2]], D[a2], AcrE, nAChRa2, Dmalpha2, CG6844-PA, nAChR Dalpha2, nAchRalpha-96Ab, Dalpha, nAChRalpha-96A, nAChRalpha2, nAChR-alpha96Ab" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002394:Nicotinic acetylcholine receptor, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG6844 11-Aug-17 DroID_v2017_08 "Drer\chrne, Drer\chrna2a, Drer\chrng, Drer\chrnb2l, Drer\chrnb3b, Drer\LOC101882451, Drer\chrna4b, Drer\si:ch211-256e16.4, Drer\chrna2b, Drer\chrna6, Drer\chrna1, Drer\chrna9, Drer\chrnb1, Drer\LOC798522, Drer\chrna5, Drer\chrnb2a, Drer\chrna10a, Drer\htr3a, Drer\htr3b, Drer\chrna3, Drer\chrnb4, Drer\chrnb1l, Drer\chrnd, Drer\chrnb2b, Drer\si:ch73-380n15.2, Drer\chrnb3a, Drer\si:ch211-39a7.1" - "Cele\eat-2, Cele\unc-38, Cele\acr-14, Cele\acr-11, Cele\acr-10, Cele\acr-12, Cele\lev-8, Cele\acr-21, Cele\lgc-4, Cele\acr-25, Cele\lev-1, Cele\acr-19, Cele\acr-9, Cele\acr-15, Cele\acr-7, Cele\unc-63, Cele\acr-3, Cele\acr-6, Cele\acr-2, Cele\acr-8, Cele\acr-16" "Xtro\chrna2, Xtro\chrna5, Xtro\chrna7, Xtro\chrne, Xtro\chrnb3, Xtro\chrna6, Xtro\chrna1.2, Xtro\chrnb2, Xtro\chrna1, Xtro\chrng, Xtro\chrna9, Xtro\chrnd" "Mmus\Htr3a, Mmus\Chrna2, Mmus\Chrna9, Mmus\Htr3b, Mmus\Chrna5, Mmus\Chrnb3, Mmus\Chrna10, Mmus\Chrnb2, Mmus\Chrnb1, Mmus\Chrna6, Mmus\Chrng, Mmus\Chrnb4, Mmus\Chrnd, Mmus\Chrne, Mmus\Chrna3, Mmus\Chrna7, Mmus\Chrna4, Mmus\Chrna1" "Hsap\HTR3C, Hsap\CHRNA7, Hsap\CHRNB2, Hsap\HTR3B, Hsap\CHRNA2, Hsap\CHRNA5, Hsap\CHRNA6, Hsap\CHRNA4, Hsap\CHRNA3, Hsap\CHRNE, Hsap\CHRNB3, Hsap\HTR3E, Hsap\CHRFAM7A, Hsap\HTR3A, Hsap\CHRNA1, Hsap\CHRNG, Hsap\CHRNA10, Hsap\CHRNB1, Hsap\CHRNB4, Hsap\HTR3D, Hsap\CHRNA9, Hsap\CHRND" " pupal stage , embryonic stage , embryonic stage | late " " embryonic central nervous system

, supraesophageal ganglion

, subesophageal ganglion

" viable DRSC24487 K 0.593513777 -0.009670847 0.269153657 0.678002676 1.812787424 1.136295682 FBgn0030692 mRpS30 mitochondrial ribosomal protein S30 http://flybase.org/reports/FBgn0030692 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9NP92 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9NP92 mitochondrial translation ; GO:0032543 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9NP92 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "mRSp30, MRP-S30, CG8470, mRpS30" IPR010793:Ribosomal protein L37/S30 CG8470 11-Aug-17 DroID_v2017_08 Drer\mrps30 - Cele\mrps-30 Xtro\mrps30 Mmus\Mrps30 Hsap\MRPS30 "viable,visible" trichogen cell FBgn0086450 su(r) suppressor of rudimentary http://flybase.org/reports/FBgn0086450 protein_coding_gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR009051 dihydroorotate dehydrogenase activity ; GO:0004152 | inferred from electronic annotation with InterPro:IPR001295 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001295, InterPro:IPR005720, InterPro:IPR023753 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from genetic interaction with r" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR005720 "su(r), Reg-3, Pyd1, Dreg-3, CG2194, pyd1" "IPR001295:Dihydroorotate dehydrogenase, conserved site, IPR005720:Dihydroorotate dehydrogenase domain, IPR009051:Alpha-helical ferredoxin, IPR013785:Aldolase-type TIM barrel, IPR017896:4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR017900:4Fe-4S ferredoxin, iron-sulphur binding, conserved site, IPR028261:Dihydroprymidine dehydrogenase domain II, IPR023753:FAD/NAD(P)-binding domain" CG2194 11-Aug-17 DroID_v2017_08 "Drer\dpyda.1, Drer\dpydb" "Scer\URA1, Scer\GLT1" Cele\dpyd-1 Xtro\dpyd Mmus\Dpyd Hsap\DPYD " embryonic stage | late , adult stage " adult head

FBgn0051326 CG31326 - http://flybase.org/reports/FBgn0051326 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "CG9645, SPH144, CG31326, cg9645" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR031986:Serine protease gd, N-terminal domain" CG31326 11-Aug-17 DroID_v2017_08 Drer\pamr1 - Cele\try-5 - - Hsap\F7 "viable,fertile" FBgn0029896 CG3168 - http://flybase.org/reports/FBgn0029896 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829, InterPro:IPR011701" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 "LP06294.5prime, BEST:LP06294, CG3168" "IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG3168 11-Aug-17 DroID_v2017_08 "Drer\sv2a, Drer\svopa, Drer\slc22a16, Drer\sv2c, Drer\slc22a7b.1, Drer\zgc:153639, Drer\slc22a21, Drer\sv2bb, Drer\sv2, Drer\sv2ba, Drer\slc22a6l, Drer\si:dkey-166k12.1, Drer\slc22a5, Drer\LOC101884074, Drer\slc22a7a" "Scer\HXT7, Scer\PHO84, Scer\HXT6, Scer\GAL2" "Cele\Y57G11C.23, Cele\C53B4.1, Cele\Y51A2D.18, Cele\oat-1, Cele\Y66D12A.13, Cele\C46C2.2, Cele\Y82E9BR.16, Cele\oct-1, Cele\ZK892.3, Cele\svop-1" "Xtro\svop, Xtro\slc22a6, Xtro\slc2a7, Xtro\sv2b, Xtro\sv2a, Xtro\slc22a5, Xtro\sv2c" "Mmus\Slc22a12, Mmus\Svop, Mmus\Slc22a21, Mmus\Slc22a5, Mmus\Slc22a6, Mmus\Sv2c, Mmus\Slc22a7, Mmus\Slc22a16, Mmus\Slc22a20, Mmus\Slc22a8, Mmus\Slc22a4, Mmus\Slc22a13, Mmus\Sv2a, Mmus\Sv2b" "Hsap\SLC22A16, Hsap\SVOP, Hsap\SLC22A20, Hsap\SV2C, Hsap\SLC22A12, Hsap\SV2B, Hsap\SLC22A4, Hsap\SLC22A13, Hsap\SLC22A8, Hsap\SLC22A7, Hsap\SV2A, Hsap\SLC22A6, Hsap\SLC22A5" FBgn0086758 chinmo Chronologically inappropriate morphogenesis http://flybase.org/reports/FBgn0086758 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 neuron development ; GO:0048666 | inferred from mutant phenotype male somatic sex determination ; GO:0019102 | inferred from mutant phenotype single-organism nuclear import ; GO:1902593 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of stem cell division ; GO:2000035 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype negative regulation of protein phosphorylation ; GO:0001933 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype inferred from genetic interaction with let-7-C nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 "Chinmo, chinmo, F, l(2)04111, CG10871, CG17156, CG17649, CG31666" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type" CG31666 11-Aug-17 DroID_v2017_08 "Drer\znf131, Drer\bcl6b, Drer\zbtb14, Drer\zbtb24, Drer\zbtb16b, Drer\bcl6a, Drer\zbtb12.2, Drer\zbtb17" - - - "Mmus\Bach2, Mmus\Hic2" "Hsap\ZBTB12, Hsap\ZBTB49, Hsap\ZBTB9, Hsap\ZBTB10, Hsap\BACH2, Hsap\ZBTB21, Hsap\HIC2" DRSC00509 IE -0.441653025 -3.462468428 -2.009506417 -1.771552176 0.486261561 -0.028031968 FBgn0027107 Inx6 Innexin 6 http://flybase.org/reports/FBgn0027107 - protein_coding_gene - medium-term memory ; GO:0072375 | inferred from mutant phenotype intercellular transport ; GO:0010496 | inferred from sequence or structural similarity with Inx3 integral component of membrane ; GO:0016021 | non-traceable author statement gap junction ; GO:0005921 | inferred from direct assay "inx-6, Dm-inx6, prp6, CG17063, FBpp0077031, inx6, Inx6" IPR000990:Innexin CG17063 11-Aug-17 DroID_v2017_08 Drer\panx3 - "Cele\inx-14, Cele\inx-19, Cele\inx-7, Cele\inx-3, Cele\inx-18, Cele\inx-15, Cele\inx-5, Cele\inx-2, Cele\inx-12, Cele\inx-16, Cele\inx-9, Cele\unc-7, Cele\inx-17, Cele\inx-22, Cele\unc-9, Cele\inx-21, Cele\inx-6, Cele\che-7, Cele\inx-8, Cele\inx-20, Cele\inx-11, Cele\inx-1, Cele\eat-5, Cele\inx-10, Cele\inx-13" - - - "memory defective,heat sensitive,viable" FBgn0040512 zetaCOP Coat Protein (coatomer) zeta http://flybase.org/reports/FBgn0040512 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR001834, InterPro:IPR017927, InterPro:IPR017938" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR001834, InterPro:IPR017927, InterPro:IPR017938 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with SGD:S000005931 phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from direct assay" COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity with SGD:S000005931 "CT13124, copz1, zetaCOP, CG3948, zetaCop, zeta-Cop" "IPR011012:Longin-like domain, IPR022775:AP complex, mu/sigma subunit, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR008333:Oxidoreductase, FAD-binding domain, IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR001709:Flavoprotein pyridine nucleotide cytochrome reductase, IPR001834:NADH:cytochrome b5 reductase (CBR), IPR017938:Riboflavin synthase-like beta-barrel" CG3948 11-Aug-17 DroID_v2017_08 "Drer\copz1, Drer\copz2" Scer\RET3 Cele\copz-1 "Xtro\copz1, Xtro\copz2" "Mmus\Copz2, Mmus\Copz1" "Hsap\COPZ2, Hsap\COPZ1" lethal DRSC11412 E -0.30202269 0.637253278 2.522808671 -4.135443287 0.046721315 0.963775547 FBgn0035355 CG16985 - http://flybase.org/reports/FBgn0035355 protein_coding_gene acyl-CoA hydrolase activity ; GO:0047617 | inferred from sequence or structural similarity with HGNC:20999 acyl-CoA hydrolase activity ; GO:0047617 | inferred from biological aspect of ancestor with PANTHER:PTN000494087 protein homotetramerization ; GO:0051289 | inferred from sequence or structural similarity with HGNC:20999 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000494087 "BcDNA:RE30174, CG16985" "IPR003736:Phenylacetic acid degradation-related domain, IPR006683:Thioesterase domain, IPR029069:HotDog domain" CG16985 11-Aug-17 DroID_v2017_08 "Drer\them4, Drer\acot13" - "Cele\F42H10.6, Cele\C25H3.14, Cele\C25H3.3" Xtro\acot13 Mmus\Acot13 Hsap\ACOT13 "viable,fertile" DRSC08501 K -0.335192919 -0.611143794 1.197770216 0.127917449 1.54774979 1.49007604 FBgn0050438 CG30438 - http://flybase.org/reports/FBgn0050438 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG30438, BcDNA:LD09936, BcDNA:RE54684, dGlcAT-BSII, GlcAT-P" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG30438 11-Aug-17 DroID_v2017_08 "Drer\ugt5f1, Drer\ugt1b7, Drer\ugt2b5, Drer\zgc:172315, Drer\ugt5g2, Drer\ugt5c1, Drer\ugt5b6, Drer\ugt1b3, Drer\ugt1b2, Drer\ugt2a6, Drer\ugt5b3, Drer\ugt5a2, Drer\ugt5g1, Drer\ugt5c3, Drer\ugt5b2, Drer\ugt5a5, Drer\ugt8, Drer\ugt1b4, Drer\ugt5a1, Drer\ugt1ab, Drer\ugt5c2, Drer\ugt1b5, Drer\ugt5e1, Drer\ugt2b3, Drer\ugt5b1, Drer\ugt2b1, Drer\ugt5d1, Drer\ugt2b6, Drer\ugt2a5, Drer\ugt2a2, Drer\ugt5a4" Scer\ATG26 "Cele\ugt-60, Cele\ugt-32, Cele\ugt-49, Cele\ugt-18, Cele\Y43D4A.2, Cele\ugt-37, Cele\C55H1.1, Cele\ugt-46, Cele\ugt-62, Cele\ugt-44, Cele\ugt-36, Cele\ugt-57, Cele\ugt-2, Cele\ugt-41, Cele\ugt-42, Cele\ugt-21, Cele\ugt-27, Cele\ugt-58, Cele\ugt-3, Cele\ugt-31, Cele\F10D2.8, Cele\C23G10.6, Cele\ugt-8, Cele\ugt-56, Cele\C03A7.12, Cele\ugt-54, Cele\ugt-34, Cele\ugt-30, Cele\ugt-47, Cele\ugt-51, Cele\ugt-24, Cele\ugt-45, Cele\ugt-12, Cele\ugt-26, Cele\H23N18.4, Cele\ugt-35, Cele\ugt-43, Cele\ugt-23, Cele\K04A8.10, Cele\ugt-10, Cele\ugt-48, Cele\ugt-19, Cele\ugt-16, Cele\ugt-28, Cele\ugt-4, Cele\ugt-53, Cele\ugt-38, Cele\ugt-22, Cele\ugt-15, Cele\ugt-59, Cele\ugt-52, Cele\ugt-39, Cele\ugt-9, Cele\ugt-25, Cele\ugt-1, Cele\ugt-6, Cele\ugt-29, Cele\ugt-11, Cele\ugt-7, Cele\ugt-5, Cele\ugt-33, Cele\ugt-40, Cele\ugt-20, Cele\ugt-14, Cele\ugt-61, Cele\ugt-13, Cele\ugt-50, Cele\ugt-17, Cele\C03A7.13, Cele\ugt-55" "Xtro\ugt2a1, Xtro\ugt1a6, Xtro\ugt3a2, Xtro\ugt2b4, Xtro\ugt8" "Mmus\Ugt3a2, Mmus\Ugt2a1, Mmus\Ugt1a7c, Mmus\Ugt2b36, Mmus\Ugt1a2, Mmus\Ugt2b34, Mmus\Ugt2b38, Mmus\Ugt3a1, Mmus\Ugt1a5, Mmus\Ugt2b35, Mmus\Ugt2b5, Mmus\Ugt1a1, Mmus\Ugt2a3, Mmus\Ugt8a, Mmus\Ugt2b37, Mmus\Ugt1a9, Mmus\Ugt2b1, Mmus\Ugt1a6b" "Hsap\UGT2B11, Hsap\UGT3A1, Hsap\UGT1A8, Hsap\UGT1A1, Hsap\UGT1A10, Hsap\UGT1A6, Hsap\UGT2B15, Hsap\UGT2A3, Hsap\UGT8, Hsap\UGT1A9, Hsap\UGT1A3, Hsap\UGT2B17, Hsap\UGT3A2, Hsap\UGT1A5, Hsap\UGT1A4, Hsap\UGT2A2, Hsap\UGT2B28, Hsap\UGT2B10, Hsap\UGT2B7, Hsap\UGT2B4, Hsap\UGT1A7" viable DRSC21419 E 0.814151657 -1.416216034 -0.605995534 -1.593239149 0.361836296 1.138546583 FBgn0027657 glob1 globin 1 http://flybase.org/reports/FBgn0027657 - protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR000971, InterPro:IPR012292 oxygen binding ; GO:0019825 | inferred from sequence model heme binding ; GO:0020037 | inferred from sequence model oxygen binding ; GO:0019825 | inferred from direct assay iron ion binding ; GO:0005506 | inferred from direct assay" "oxygen transport ; GO:0015671 | inferred by curator from GO:0005506,GO:0019825 sleep ; GO:0030431 | inferred from expression pattern" cytoplasm ; GO:0005737 | inferred from sequence model "DmHb, Glob1, DmeGlob1, Hb, dmeglob1, CG9734, glob1, DmeGb1, DmHb1, globin1" "IPR000971:Globin, IPR009050:Globin-like" CG9734 11-Aug-17 DroID_v2017_08 "Drer\si, Drer\hbbe1.1, Drer\hbaa1, Drer\ngb, Drer\mb, Drer\si:ch211-5k11.8, Drer\ba1, Drer\cygb2, Drer\ba2, Drer\cygb1, Drer\hbae1, Drer\hbz, Drer\si:ch211-5k11.12, Drer\zgc:92880, Drer\zgc:163057, Drer\MGC173646, Drer\si:ch211-5k11.2, Drer\hbbe3, Drer\LOC100334599, Drer\si:ch211-5k11.6, Drer\hbbe2, Drer\ba1l, Drer\hbae3" "Scer\YHB1, Scer\YNL234W" "Cele\glb-17, Cele\glb-8, Cele\Y57G11B.97, Cele\glb-21, Cele\glb-14" "Xtro\hbg1, Xtro\LOC100145107, Xtro\hba4, Xtro\cygb, Xtro\hba1, Xtro\hba3, Xtro\hbd, Xtro\hbe1, Xtro\hbz, Xtro\ngb, Xtro\hbg2" "Mmus\Hbb-b1, Mmus\Hbb-bh2, Mmus\Hba-x, Mmus\Hbb-bh1, Mmus\Cygb, Mmus\Mb, Mmus\Hbq1a, Mmus\Hbb-b2, Mmus\Hbb-bt, Mmus\Hbb-bs, Mmus\Hba-a1, Mmus\Hbq1b, Mmus\Hbb-y, Mmus\Ngb, Mmus\Hba-a2" "Hsap\HBA1, Hsap\HBM, Hsap\CYGB, Hsap\HBB, Hsap\HBE1, Hsap\HBQ1, Hsap\HBD, Hsap\HBG2, Hsap\NGB, Hsap\HBG1, Hsap\HBZ, Hsap\MB, Hsap\HBA2" viable FBgn0039671 CG11470 - http://flybase.org/reports/FBgn0039671 protein_coding_gene - - - CG11470 IPR007931:Protein of unknown function DUF725 CG11470 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC14313 K -0.342770977 -0.610995523 0.422935057 0.092421448 1.9276504 0.05829375 FBgn0033846 mip120 Myb-interacting protein 120 http://flybase.org/reports/FBgn0033846 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with HDAC1 DNA binding ; GO:0003677 | inferred from direct assay oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype eggshell chorion gene amplification ; GO:0007307 | inferred by curator from GO:0031523 flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype chromatin ; GO:0000785 | inferred from direct assay Myb complex ; GO:0031523 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "Mip120, CG6061, p120, l(3)L4569, mip120, MIP120" "IPR005172:CRC domain, IPR028307:Lin-54 family, IPR033467:Tesmin/TSO1-like CXC domain" CG6061 11-Aug-17 DroID_v2017_08 "Drer\mtl5, Drer\lin54" - Cele\lin-54 Xtro\lin54 "Mmus\Mtl5, Mmus\Lin54" "Hsap\LIN54, Hsap\TESMIN" "viable,reduced,visible,female sterile,recessive,male sterile,lethal,neuroanatomy defective" "eye,egg chamber,nucleus & nurse cell,nucleus & follicle cell,spermatozoon,neurite | pharate adult stage" DRSC06960 IE 2.308713766 -0.745895076 1.781550961 -2.088495671 1.010031817 -0.191092685 FBgn0053193 sav salvador http://flybase.org/reports/FBgn0053193 protein_coding_gene protein complex scaffold ; GO:0032947 | inferred from electronic annotation with InterPro:IPR030030 protein binding ; GO:0005515 | inferred from physical interaction with Mer inferred from physical interaction with kibra protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VY77 protein binding ; GO:0005515 | inferred from physical interaction with hpo hippo signaling ; GO:0035329 | inferred from electronic annotation with InterPro:IPR030030 imaginal disc development ; GO:0007444 | inferred from mutant phenotype retinal cell programmed cell death ; GO:0046666 | inferred from mutant phenotype inferred from genetic interaction with hid stem cell differentiation ; GO:0048863 | inferred from mutant phenotype Malpighian tubule development ; GO:0072002 | inferred from mutant phenotype R8 cell fate specification ; GO:0045464 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from genetic interaction with wts regulation of imaginal disc growth ; GO:0045570 | traceable author statement regulation of cell proliferation ; GO:0042127 | traceable author statement hippo signaling ; GO:0035329 | traceable author statement negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype negative regulation of organ growth ; GO:0046621 | traceable author statement stem cell proliferation ; GO:0072089 | inferred from mutant phenotype adherens junction ; GO:0005912 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "sav, Salvador/Shar-pei, shar-pei, CG13831, CG33193, CG13832, anon-WO0172774.152, Sav" "IPR001202:WW domain, IPR011524:SARAH domain, IPR030030:Scaffold protein salvador" CG33193 11-Aug-17 DroID_v2017_08 Drer\sav1 - Cele\sav-1 Xtro\sav1 Mmus\Sav1 Hsap\SAV1 "visible,somatic clone,lethal,increased cell number,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,progressive,stress response defective,cell polarity defective,large body,size defective,small body,partially lethal - majority die,body color defective" "eye,somatic clone,pigment cell,ectopic,interommatidial bristle,supernumerary,cell cycle | somatic clone,haltere,mesothoracic tergum,eye photoreceptor cell,eye disc,progressive,autophagic vacuole | progressive | somatic clone,dorsal multidendritic neuron ddaC | somatic clone & dendritic tree,adult Malpighian tubule,adult head,cell autonomous,ommatidial precursor cluster,photoreceptor cell R8 of yellow ommatidium,photoreceptor cell R8 of pale ommatidium,wing,posterior,adult thorax,wing disc,chaeta,trichogen cell" FBgn0036809 CG12477 - http://flybase.org/reports/FBgn0036809 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:7112 zinc ion binding ; GO:0008270 | inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:7112 cellular_component ; GO:0005575 | no biological data available CG12477 "IPR000571:Zinc finger, CCCH-type, IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR018957:Zinc finger, C3HC4 RING-type" CG12477 11-Aug-17 DroID_v2017_08 "Drer\rnf141, Drer\mkrn1, Drer\mkrn2, Drer\mkrn4" Scer\LEE1 "Cele\ccch-1, Cele\Y55F3AM.6" "Xtro\mkrn3, Xtro\mkrn1, Xtro\mkrn2, Xtro\rnf141" "Mmus\Rnf141, Mmus\Mkrn1, Mmus\Mkrn3, Mmus\Mkrn2" "Hsap\MKRN3, Hsap\MKRN2, Hsap\MKRN1, Hsap\RNF141" "sleep defective,female limited,viable" FBgn0002782 moo moorish http://flybase.org/reports/FBgn0002782 - gene - - - "mo, moo" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,body color defective" FBgn0015873 anon-48Ab anon-48Ab http://flybase.org/reports/FBgn0015873 - gene - - - "II, anon-48Ab" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001657 l(1)ds11 lethal (1) discs small 11 http://flybase.org/reports/FBgn0001657 - gene - - - "l(1)1-43, l(1)ds11" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,ring gland" FBgn0037156 CG11523 - http://flybase.org/reports/FBgn0037156 protein_coding_gene - - - CG11523 "IPR007967:Protein of unknown function DUF727, IPR023231:GSKIP domain" CG11523 11-Aug-17 DroID_v2017_08 Drer\gskip - "Cele\C06A12.3, Cele\T24H7.3, Cele\Y43F8B.2" Xtro\gskip Mmus\Gskip Hsap\GSKIP "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0034365 CG5335 - http://flybase.org/reports/FBgn0034365 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR001079 - - CG5335 "IPR001079:Galectin, carbohydrate recognition domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG5335 11-Aug-17 DroID_v2017_08 "Drer\lgals9l1, Drer\lgals1l1, Drer\lgalslb, Drer\si:ch211-10a23.2, Drer\lgals9l6, Drer\grifin, Drer\lgals3b, Drer\lgals9l5, Drer\lgals9l4, Drer\lgals3a, Drer\lgalsla, Drer\lgals9l3, Drer\lgals2a, Drer\lgals8a, Drer\lgals8b, Drer\lgals2b" - "Cele\lec-5, Cele\lec-3, Cele\F46A8.3, Cele\F46A8.4, Cele\F49F1.11, Cele\F46A8.5, Cele\F49F1.10, Cele\F49F1.9, Cele\C27C7.5, Cele\T02G6.7, Cele\lec-4, Cele\C53D6.7, Cele\F46A8.8, Cele\lec-12, Cele\lec-1, Cele\F49F1.18" "Xtro\lgals9b, Xtro\lgals1, Xtro\LOC100216286, Xtro\lgals2, Xtro\lgals8, Xtro\LOC100496749, Xtro\lgals9, Xtro\lgals9c, Xtro\lgalsl, Xtro\lgals4, Xtro\lgals3" "Mmus\Lgals7, Mmus\Lgals9, Mmus\Grifin, Mmus\Lgals1, Mmus\Lgals8, Mmus\Lgalsl, Mmus\Lgals3, Mmus\Lgals12, Mmus\Lgals2, Mmus\Lgals4" "Hsap\LGALS9C, Hsap\LGALS13, Hsap\LGALS9, Hsap\LGALS1, Hsap\OSTC, Hsap\CLC, Hsap\LGALS8, Hsap\LGALS9B, Hsap\LGALS7B, Hsap\LGALS4, Hsap\LGALS3, Hsap\LGALSL, Hsap\LGALS2, Hsap\LGALS12, Hsap\GRIFIN, Hsap\LGALS14, Hsap\LGALS7" viable FBgn0000254 Cbp82F Calmodulin-binding protein 82F http://flybase.org/reports/FBgn0000254 - gene - - - "Cal82F, Cbp82F" - - 11-Aug-17 DroID_v2017_08 - - - - - - adult stage adult head

FBgn0004791 ray rayon http://flybase.org/reports/FBgn0004791 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ray - - 11-Aug-17 DroID_v2017_08 - - - - - - female sterile FBgn0004154 l(2)51Da lethal (2) 51Da http://flybase.org/reports/FBgn0004154 - gene - - - l(2)51Da - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage" FBgn0029034 l(2)Q39 lethal (2) Q39 http://flybase.org/reports/FBgn0029034 gene - - - "Q39, l(2)Q39" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0260660 Mp Multiplexin http://flybase.org/reports/FBgn0260660 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR010515 carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR010515 basement membrane organization ; GO:0071711 | inferred from mutant phenotype cardiac muscle atrophy ; GO:0014899 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype skeletal muscle atrophy ; GO:0014732 | inferred from mutant phenotype positive regulation of integrin-mediated signaling pathway ; GO:2001046 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype extracellular matrix ; GO:0031012 | inferred from electronic annotation with InterPro:IPR010515 collagen trimer ; GO:0005581 | inferred from sequence or structural similarity "Mp, dmp, CG33171, CG8647, COL18A1, CT14872, CG14822, CG8645, Dmp, CG42543, mp" "IPR001791:Laminin G domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR008160:Collagen triple helix repeat, IPR010515:Collagenase NC10/endostatin, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG42543 11-Aug-17 DroID_v2017_08 "Drer\col27a1a, Drer\col9a2, Drer\col28a1a, Drer\col4a5, Drer\col9a1a, Drer\LOC100538221, Drer\si:ch211-196i2.1, Drer\col2a1b, Drer\si:ch211-106n13.3, Drer\col9a1b, Drer\col4a2, Drer\col6a4a, Drer\col12a1b, Drer\col14a1a, Drer\col11a1a, Drer\col1a1a, Drer\col15a1b, Drer\col1a2, Drer\col4a6, Drer\wu:fc38h03, Drer\col17a1b, Drer\col7a1l, Drer\col5a2a, Drer\col5a1, Drer\col27a1b, Drer\col2a1a, Drer\zgc:153049, Drer\col5a2b, Drer\col18a1, Drer\LOC101884357, Drer\col1a1b, Drer\c1ql3a, Drer\LOC101883924, Drer\col16a1, Drer\col11a1b, Drer\col15a1a, Drer\col11a2, Drer\col6a1, Drer\col6a2, Drer\si:dkey-61l1.4, Drer\si:dkey-225n22.4, Drer\col6a3" - "Cele\mec-5, Cele\cle-1" "Xtro\col4a5, Xtro\col2a1, Xtro\col11a2, Xtro\col7a1, Xtro\col27a1, Xtro\col6a2, Xtro\col18a1, Xtro\col14a1, Xtro\col3a1, Xtro\col4a1, Xtro\LOC100486063, Xtro\col4a2, Xtro\col5a1, Xtro\col1a2, Xtro\col24a1, Xtro\col1a1, Xtro\col4a6" "Mmus\Col4a1, Mmus\Col6a3, Mmus\8030474K03Rik, Mmus\Col9a3, Mmus\Col24a1, Mmus\Col7a1, Mmus\Col4a2, Mmus\Col11a1, Mmus\Col3a1, Mmus\Col6a4, Mmus\Col22a1, Mmus\Col4a3, Mmus\Col23a1, Mmus\Col6a5, Mmus\Col17a1, Mmus\Col1a1, Mmus\Col18a1, Mmus\Col1a2, Mmus\Col5a3, Mmus\Col5a1, Mmus\Col5a2, Mmus\Col20a1, Mmus\Col27a1, Mmus\Col6a6, Mmus\C1ql3, Mmus\Tnn, Mmus\Col13a1, Mmus\Vwa2, Mmus\Col6a1, Mmus\Col9a1, Mmus\Col4a5, Mmus\Col15a1, Mmus\Col4a4, Mmus\Col11a2, Mmus\Col14a1, Mmus\Col28a1, Mmus\Col25a1, Mmus\Vwa1, Mmus\Col4a6, Mmus\4933412E24Rik, Mmus\Col19a1, Mmus\Col16a1, Mmus\Col2a1" "Hsap\COL23A1, Hsap\COL7A1, Hsap\COL5A1, Hsap\COL9A2, Hsap\COL18A1, Hsap\COL27A1, Hsap\COL24A1, Hsap\COL22A1, Hsap\COL9A3, Hsap\COL6A5, Hsap\COL4A2, Hsap\COL6A1, Hsap\COL11A2, Hsap\COL3A1, Hsap\COL4A1, Hsap\COL1A1, Hsap\COL16A1, Hsap\COL4A4, Hsap\COL15A1, Hsap\VWA2, Hsap\COL19A1, Hsap\COL5A2, Hsap\COL4A3, Hsap\COL11A1, Hsap\COL25A1, Hsap\COL2A1, Hsap\COL9A1, Hsap\COL17A1, Hsap\COL1A2, Hsap\COL14A1, Hsap\COL5A3, Hsap\COL4A5, Hsap\COL4A6, Hsap\VWA1, Hsap\COLQ, Hsap\COL20A1, Hsap\COL6A6, Hsap\COL6A3" FBgn0053082 CG33082 - http://flybase.org/reports/FBgn0053082 protein_coding_gene ribonuclease P activity ; GO:0004526 | contributes_to inferred from sequence or structural similarity with SGD:S000001454 tRNA processing ; GO:0008033 | inferred from sequence or structural similarity with SGD:S000001454 nucleolar ribonuclease P complex ; GO:0005655 | inferred from sequence or structural similarity with SGD:S000001454 CG33082 "IPR007175:RNAse P, Rpr2/Rpp21 subunit" CG33082 11-Aug-17 DroID_v2017_08 Drer\rpp21 Scer\RPR2 - Xtro\rpp21 Mmus\Rpp21 "Hsap\TRIM39-RPP21, Hsap\RPP21" FBgn0030774 spheroide spheroide http://flybase.org/reports/FBgn0030774 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred by curator from GO:0050832 "SPH114, anon-WO0140519.154, anon-EST:ParkEST153, spheroide, CG9675, Spheroide" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG9675 11-Aug-17 DroID_v2017_08 Drer\st14b - - - - Hsap\PRSS38 immune response defective FBgn0263120 Acsl Acyl-CoA synthetase long-chain http://flybase.org/reports/FBgn0263120 protein_coding_gene "long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from sequence or structural similarity with HGNC:3570,HGNC:3571" "early endosome to recycling endosome transport ; GO:0061502 | inferred from mutant phenotype positive regulation of sequestering of triglyceride ; GO:0010890 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of BMP signaling pathway ; GO:0030514 | inferred from mutant phenotype inferred from genetic interaction with tkv inferred from genetic interaction with Dad segmentation ; GO:0035282 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype long-chain fatty acid metabolic process ; GO:0001676 | inferred from sequence or structural similarity with HGNC:3570,HGNC:3571" axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "Acsl, CG8732, dAcsl, l(2)44DEa, l(2)k05304, l(2)7447, 7447, l(2)05847, anon-WO0172774.173, FCS, dFAC, FACS, l(2)SH0465, l(2)SH2 0465" "IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase, IPR020845:AMP-binding, conserved site" CG8732 11-Aug-17 DroID_v2017_08 "Drer\acsl2, Drer\acsbg1, Drer\acsl3a, Drer\acsl1b, Drer\acsl3b, Drer\acsl1a, Drer\acsl5, Drer\acsl6, Drer\acsl4b, Drer\acsl4a, Drer\acsbg2" "Scer\FAA4, Scer\FAA2, Scer\FAA3, Scer\FAA1" "Cele\acs-17, Cele\acs-5, Cele\acs-4, Cele\acs-13" "Xtro\acsl1, Xtro\acsl6, Xtro\acsbg1, Xtro\acsl3, Xtro\acsl5, Xtro\acsbg2, Xtro\acsl4" "Mmus\Acsbg2, Mmus\1700061G19Rik, Mmus\Acsl3, Mmus\Acsl4, Mmus\Acsbg1, Mmus\Acsl5, Mmus\Acsl1, Mmus\Acsl6" "Hsap\ACSL3, Hsap\ACSBG2, Hsap\ACSL1, Hsap\ACSBG1, Hsap\ACSL6, Hsap\ACSL4, Hsap\ACSL5" DRSC07252 I 1.596669266 0.039032602 0.392512877 -1.006107434 -0.124193614 -0.630966628 FBgn0034160 CG5550 - http://flybase.org/reports/FBgn0034160 protein_coding_gene - - - "CG5550, AAL48972, AAF57948, FBpp0086184" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR020837:Fibrinogen, conserved site, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG5550 11-Aug-17 DroID_v2017_08 "Drer\fibcd1, Drer\tnxba, Drer\zgc:173915, Drer\angptl6, Drer\si:zfos-2330d3.6, Drer\si:ch211-157b11.8, Drer\tnw, Drer\si:zfos-2330d3.3, Drer\fga, Drer\tnr, Drer\fgl2b, Drer\angptl7, Drer\si:ch211-203k16.3, Drer\wu:fj11g02, Drer\angpt2a, Drer\angpt2b, Drer\tnc, Drer\zmp:0000000846, Drer\angptl4, Drer\angptl5, Drer\si:ch1073-110a20.2, Drer\si:zfos-2330d3.8, Drer\si:zfos-2330d3.1, Drer\fgl1, Drer\LOC555374, Drer\si:ch211-287a12.9, Drer\si:ch1073-110a20.3, Drer\angpt1, Drer\fgl2a, Drer\si:ch1073-110a20.1, Drer\LOC100007488, Drer\fgg, Drer\fgb, Drer\angpt4, Drer\mfap4, Drer\zgc:171687, Drer\si:dkeyp-51b7.3, Drer\angptl2b, Drer\angptl1a, Drer\angptl3, Drer\angptl2a, Drer\zgc:194887" - "Cele\C08G9.2, Cele\Y69H2.10, Cele\ZC504.1, Cele\Y69H2.3, Cele\T15B7.1, Cele\K10D3.4, Cele\ensh-1, Cele\Y26D4A.12, Cele\W05B2.2, Cele\Y43C5A.2" "Xtro\fgl2, Xtro\LOC100488177, Xtro\fibcd1, Xtro\fgl1, Xtro\MGC107908, Xtro\fgb, Xtro\angpt1, Xtro\MGC108470, Xtro\tnxb, Xtro\LOC100497330, Xtro\tnn, Xtro\fcn2, Xtro\tnr, Xtro\fcn3, Xtro\LOC100491028, Xtro\fga, Xtro\angptl5, Xtro\angptl3, Xtro\angptl2, Xtro\angpt4, Xtro\fgg, Xtro\LOC100495637, Xtro\mfap4, Xtro\angptl4, Xtro\fcn1, Xtro\tnc, Xtro\LOC100491105" "Mmus\Fgb, Mmus\Fibcd1, Mmus\Angpt1, Mmus\Tnc, Mmus\Tnr, Mmus\Tnn, Mmus\Fga, Mmus\Angptl3, Mmus\Fgl2, Mmus\Angpt2, Mmus\Fcnb, Mmus\Angptl7, Mmus\Angpt4, Mmus\Fgg, Mmus\Fgl1, Mmus\Angptl2, Mmus\Fcna, Mmus\Angptl1, Mmus\Mfap4, Mmus\Angptl4, Mmus\Angptl6, Mmus\Tnxb" "Hsap\TNN, Hsap\FGL1, Hsap\FCN1, Hsap\ANGPTL1, Hsap\FGA, Hsap\ANGPT1, Hsap\FGL2, Hsap\TNR, Hsap\FGG, Hsap\ANGPT2, Hsap\MFAP4, Hsap\ANGPTL7, Hsap\ANGPTL5, Hsap\FCN2, Hsap\FCN3, Hsap\ANGPTL6, Hsap\FGB, Hsap\ANGPT4, Hsap\ANGPTL2, Hsap\TNXB, Hsap\ANGPTL3, Hsap\TNC, Hsap\ANGPTL4, Hsap\FIBCD1" viable FBgn0031534 Snx1 Sorting nexin 1 http://flybase.org/reports/FBgn0031534 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from sequence or structural similarity with SGD:S000005595 protein transporter activity ; GO:0008565 | contributes_to inferred from sequence or structural similarity with SGD:S000005595 "endocytosis ; GO:0006897 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 positive regulation of Wnt protein secretion ; GO:0061357 | NOT inferred from mutant phenotype vesicle organization ; GO:0016050 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 early endosome to Golgi transport ; GO:0034498 | inferred from biological aspect of ancestor with PANTHER:PTN000831110 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with SGD:S000005595" "extrinsic component of membrane ; GO:0019898 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 retromer, tubulation complex ; GO:0030905 | inferred from sequence or structural similarity with SGD:S000005595 endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN000831110 endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000005595" "CG2774, Vps5, Dsnx1, Snx1" "IPR001683:Phox homologous domain, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR015404:Sorting nexin Vps5-like, C-terminal" CG2774 11-Aug-17 DroID_v2017_08 "Drer\snx1b, Drer\snx2, Drer\snx4, Drer\snx30, Drer\snx8b, Drer\snx18a, Drer\snx1a, Drer\snx33, Drer\snx9b, Drer\snx8a" "Scer\VPS5, Scer\YKR078W, Scer\ATG20, Scer\SNX4, Scer\SNX41, Scer\VPS17, Scer\SNX3, Scer\MVP1" "Cele\lst-4, Cele\snx-1, Cele\snx-6" "Xtro\snx30, Xtro\snx1, Xtro\snx33, Xtro\snx2, Xtro\snx7" "Mmus\Snx2, Mmus\Snx33, Mmus\Snx8, Mmus\Snx30, Mmus\Snx7, Mmus\Snx9, Mmus\Snx1, Mmus\Snx18" "Hsap\SNX7, Hsap\SNX30, Hsap\SNX2, Hsap\SNX4, Hsap\SNX33, Hsap\SNX1, Hsap\SNX8, Hsap\SNX18" "viable,fertile" FBgn0032683 kon kon-tiki http://flybase.org/reports/FBgn0032683 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Grip positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype inferred from genetic interaction with mew inferred from genetic interaction with Grip sarcomere organization ; GO:0045214 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype muscle tendon junction ; GO:0005927 | inferred from direct assay cell tip ; GO:0051286 | inferred from direct assay costamere ; GO:0043034 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay "CT28869, CG10275, kon, perd, Kon" "IPR001791:Laminin G domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG10275 11-Aug-17 DroID_v2017_08 "Drer\frem2a, Drer\cspg4, Drer\frem2b, Drer\frem1b, Drer\frem3, Drer\si:dkeyp-41f9.3, Drer\si:dkey-193c22.2, Drer\fras1, Drer\frem1a" - Cele\C48E7.6 "Xtro\cspg4, Xtro\frem1, Xtro\frem3, Xtro\fras1" "Mmus\Frem3, Mmus\Frem1, Mmus\Frem2, Mmus\Fras1, Mmus\Cspg4" "Hsap\FREM2, Hsap\FRAS1, Hsap\CSPG4, Hsap\FREM3, Hsap\FREM1" "visible,lethal,viable,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic somatic muscle,filopodium | ectopicMef2.PR,wing,ventral longitudinal muscle,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,embryonic/larval neuroblast,ganglion mother cell,embryonic/larval somatic muscle,segment border muscle,epithelium,female germline cyst" FBgn0034748 CG17807 - http://flybase.org/reports/FBgn0034748 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors ; GO:0016706 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 tRNA (uracil) methyltransferase activity ; GO:0016300 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 ferrous iron binding ; GO:0008198 | inferred from biological aspect of ancestor with PANTHER:PTN001405577" tRNA methylation ; GO:0030488 | inferred from electronic annotation with InterPro:IPR032863 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 tRNA wobble uridine modification ; GO:0002098 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 CG17807 "IPR027450:Alpha-ketoglutarate-dependent dioxygenase AlkB-like, IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR013216:Methyltransferase type 11, IPR032863:Alkylated DNA repair protein alkB homologue 8, IPR034256:ALKBH8, RNA recognition motif, IPR000504:RNA recognition motif domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG17807 11-Aug-17 DroID_v2017_08 "Drer\zgc:73340, Drer\alkbh7, Drer\alkbh8" Scer\TRM9 "Cele\C35D10.12, Cele\alkb-8" "Xtro\alkbh7, Xtro\alkbh8, Xtro\kiaa1456" "Mmus\Alkbh8, Mmus\Alkbh7, Mmus\6430573F11Rik" "Hsap\KIAA1456, Hsap\ALKBH8, Hsap\ALKBH7" viable heart primordium FBgn0027602 CG8611 - http://flybase.org/reports/FBgn0027602 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000001732 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "DmRH11, cg8611, BcDNA:GH02833, CG8611" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR025313:Domain of unknown function DUF4217, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8611 11-Aug-17 DroID_v2017_08 Drer\ddx31 Scer\DBP7 - Xtro\ddx31 Mmus\Ddx31 Hsap\DDX31 viable FBgn0001125 Got2 Glutamate oxaloacetate transaminase 2 http://flybase.org/reports/FBgn0001125 FBgn0031380 protein_coding_gene "pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004838, InterPro:IPR004839 L-aspartate:2-oxoglutarate aminotransferase activity ; GO:0004069 | inferred from direct assay L-aspartate:2-oxoglutarate aminotransferase activity ; GO:0004069 | inferred from sequence or structural similarity with UniProtKB:P00505" glutamate biosynthetic process ; GO:0006537 | inferred from direct assay glutamate biosynthetic process ; GO:0006537 | inferred from mutant phenotype neurotransmitter receptor metabolic process ; GO:0045213 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from mutant phenotype aspartate catabolic process ; GO:0006533 | inferred from biological aspect of ancestor with PANTHER:PTN000222759 aspartate metabolic process ; GO:0006531 | inferred from sequence or structural similarity with UniProtKB:P00505 mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P00505 "152801_at, got2, Got, Got-2, CG4233, Got2, Got 2" "IPR000796:Aspartate/other aminotransferase, IPR004838:Aminotransferases, class-I, pyridoxal-phosphate-binding site, IPR004839:Aminotransferase, class I/classII, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG4233 11-Aug-17 DroID_v2017_08 "Drer\got2b, Drer\got1, Drer\got2a" "Scer\AAT1, Scer\AAT2" "Cele\got-2.2, Cele\got-2.1, Cele\got-1.2" "Xtro\got2, Xtro\got1" "Mmus\Got2, Mmus\Got1, Mmus\Got1l1" "Hsap\GOT1L1, Hsap\GOT1, Hsap\GOT2" "viable,electrophoretic variant,neurophysiology defective,fertile" larval neuromuscular junction & postsynaptic membrane DRSC00643 K -0.255834431 0.275376617 0.283950443 0.444125638 1.596885102 0.66705571 FBgn0042712 HBS1 HBS1 http://flybase.org/reports/FBgn0042712 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161 protein binding ; GO:0005515 | inferred from physical interaction with pelo GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000561878" positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype posttranscriptional gene silencing ; GO:0016441 | inferred from mutant phenotype translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN000561878 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000561878 "CG1898, HBS1, Hbs1, hbs1" "IPR000795:Transcription factor, GTP-binding domain, IPR004160:Translation elongation factor EFTu/EF1A, C-terminal, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR015033:HBS1-like protein, N-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1898 11-Aug-17 DroID_v2017_08 "Drer\hbs1l, Drer\gspt1" "Scer\SUP35, Scer\SKI7, Scer\HBS1" Cele\K07A12.4 "Xtro\gspt1, Xtro\hbs1l" "Mmus\Gspt1, Mmus\Hbs1l, Mmus\Gspt2" "Hsap\GSPT2, Hsap\HBS1L, Hsap\GSPT1" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC08544 IE 0.394461906 -1.782525663 -1.82912055 0.462734984 0.122304821 -0.618682845 FBgn0013303 Nca Neurocalcin http://flybase.org/reports/FBgn0013303 FBgn0013306 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from direct assay - - "Ncalc, nca, CG7641, Nca" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG7641 11-Aug-17 DroID_v2017_08 "Drer\ncs1a, Drer\ncalda, Drer\si:ch211-103a14.5, Drer\hpcal1, Drer\kcnip4, Drer\si:ch211-245j22.3, Drer\kcnip1a, Drer\rcvrna, Drer\guca1b, Drer\guca1d, Drer\guca1g, Drer\si:ch211-145b13.5, Drer\guca1c, Drer\vsnl1a, Drer\ncs1b, Drer\hpca, Drer\ncaldb, Drer\rcvrn2, Drer\kcnip1b, Drer\usp32, Drer\guca1a, Drer\hpcal4, Drer\efcab1, Drer\rcvrnb, Drer\kcnip2, Drer\kcnip3b, Drer\guca1e, Drer\vsnl1b, Drer\rcvrn3" Scer\FRQ1 "Cele\rsa-1, Cele\ncs-3, Cele\ncs-1, Cele\ncs-2" "Xtro\kcnip2, Xtro\guca1b, Xtro\efcab1, Xtro\hpca, Xtro\vsnl1, Xtro\guca1a, Xtro\kcnip1, Xtro\rcvrn.2, Xtro\guca1c, Xtro\hpcal1, Xtro\kcnip4, Xtro\ncs1, Xtro\kcnip3, Xtro\ncald" "Mmus\1700109H08Rik, Mmus\Rcvrn, Mmus\Kcnip1, Mmus\Usp32, Mmus\Vsnl1, Mmus\Hpcal1, Mmus\Kcnip3, Mmus\Guca1b, Mmus\Hpca, Mmus\Ncald, Mmus\Guca1a, Mmus\Kcnip4, Mmus\Kcnip2, Mmus\Ncs1, Mmus\Hpcal4, Mmus\Efcab1" "Hsap\KCNIP1, Hsap\HPCAL4, Hsap\GUCA1B, Hsap\NCALD, Hsap\USP32, Hsap\EFCAB1, Hsap\GUCA1C, Hsap\KCNIP4, Hsap\HPCAL1, Hsap\GUCA1A, Hsap\RCVRN, Hsap\KCNIP3, Hsap\HPCA, Hsap\KCNIP2, Hsap\NCS1, Hsap\VSNL1" FBgn0001248 Idh Isocitrate dehydrogenase http://flybase.org/reports/FBgn0001248 "FBgn0013617, FBgn0035881" protein_coding_gene NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR019818 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR019818 hydroxyacid-oxoacid transhydrogenase activity ; GO:0047988 | inferred from mutant phenotype isocitrate dehydrogenase (NADP+) activity ; GO:0004450 | inferred from direct assay isocitrate dehydrogenase (NADP+) activity ; GO:0004450 | inferred from sequence or structural similarity with UniProtKB:P48735 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P48735 fatty acid alpha-oxidation ; GO:0001561 | non-traceable author statement isocitrate metabolic process ; GO:0006102 | inferred from direct assay glyoxylate cycle ; GO:0006097 | inferred from sequence or structural similarity with UniProtKB:P48735 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P48735 lipid particle ; GO:0005811 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:5382 "Idh, CT22171, CG7176, l(3)L3852, IDH-NADP, idh, IDH, Idh-NADP, isocitrate dehydrogenase, ICDH, cIdh" "IPR004790:Isocitrate dehydrogenase NADP-dependent, IPR019818:Isocitrate/isopropylmalate dehydrogenase, conserved site, IPR024084:Isopropylmalate dehydrogenase-like domain" CG7176 11-Aug-17 DroID_v2017_08 Drer\idh1 "Scer\IDP3, Scer\IDP2, Scer\IDP1" "Cele\idh-2, Cele\idh-1" "Xtro\idh2, Xtro\idh1" "Mmus\Idh2, Mmus\Idh1" "Hsap\IDH2, Hsap\IDH1" "lethal,recessive,viable,fertile,electrophoretic variant,visible" trichogen cell DRSC10779 K 1.223779142 -0.336173402 -0.027874849 0.141519918 0.549240438 1.578174883 FBgn0035488 CG11593 - http://flybase.org/reports/FBgn0035488 protein_coding_gene - - - "anon-EST:Posey64, CG11593" "IPR001251:CRAL-TRIO lipid binding domain, IPR022181:Bcl2-/adenovirus E1B 19kDa-interacting protein 2" CG11593 11-Aug-17 DroID_v2017_08 "Drer\bnip2, Drer\prune2, Drer\atcayb, Drer\bnipl, Drer\atcaya" Scer\PPX1 - "Xtro\bnipl, Xtro\atcay, Xtro\bnip2, Xtro\prune2" "Mmus\Atcay, Mmus\Prune2, Mmus\Bnipl, Mmus\Bnip2" "Hsap\ATCAY, Hsap\PRUNE2, Hsap\BNIP2, Hsap\BNIPL" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038723 CG6195 - http://flybase.org/reports/FBgn0038723 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006073, InterPro:IPR006074, InterPro:IPR031167" - - "BEST:GH15838, CG6195" "IPR004095:TGS, IPR005225:Small GTP-binding protein domain, IPR006073:GTP binding domain, IPR006074:GTP1/OBG, conserved site, IPR012676:TGS-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR012675:Beta-grasp domain, IPR031167:OBG-type guanine nucleotide-binding (G) domain, IPR031662:GTP binding protein, second domain" CG6195 11-Aug-17 DroID_v2017_08 "Drer\drg2, Drer\drg1" Scer\RBG2 "Cele\T28D6.6, Cele\C02F5.3" "Xtro\drg2, Xtro\drg1" "Mmus\Drg2, Mmus\Drg1" "Hsap\DRG2, Hsap\DRG1" FBgn0039135 CG13603 - http://flybase.org/reports/FBgn0039135 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern - CG13603 - CG13603 11-Aug-17 DroID_v2017_08 "Drer\zgc:110591, Drer\LOC100537383, Drer\zgc:153018, Drer\tmem179b, Drer\tmem179" - - Xtro\tmem179 "Mmus\Tmem179, Mmus\Tmem179b" "Hsap\TMEM179, Hsap\TMEM179B" viable FBgn0011016 SsRbeta Signal sequence receptor beta http://flybase.org/reports/FBgn0011016 "FBgn0026009, FBgn0027883" protein_coding_gene signal sequence binding ; GO:0005048 | inferred from sequence or structural similarity cotranslational protein targeting to membrane ; GO:0006613 | inferred from biological aspect of ancestor with PANTHER:PTN000304850 protein retention in ER lumen ; GO:0006621 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008856 lipid particle ; GO:0005811 | inferred from direct assay signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000983375" "l(3)s1939, BcDNA.LD10457, clone 1.1, SsRbeta, anon-EST:Liang-1.1, CG5474, BcDNA:LD10457" "IPR008856:Translocon-associated protein subunit beta, IPR013783:Immunoglobulin-like fold" CG5474 11-Aug-17 DroID_v2017_08 Drer\ssr2 - "Cele\trap-2, Cele\K08F4.3" Xtro\ssr2 Mmus\Ssr2 Hsap\SSR2 "lethal,recessive,viable,fertile" FBgn0052808 CG32808 - http://flybase.org/reports/FBgn0052808 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "EG:80H7.1, CG32808" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG32808 11-Aug-17 DroID_v2017_08 "Drer\gzma, Drer\si:dkey-78l4.4, Drer\si:dkey-78l4.13, Drer\si:dkey-78l4.6, Drer\si:ch211-212d10.1, Drer\gzm3, Drer\zgc:92041, Drer\si:dkey-78l4.12, Drer\si:dkey-78l4.1, Drer\si:dkey-21e2.16, Drer\zgc:112368, Drer\zgc:92511, Drer\si:dkey-78l4.8, Drer\LOC558805, Drer\si:dkey-78l4.7, Drer\si:ch211-165b19.9, Drer\si:dkey-78l4.10, Drer\si:ch211-165b19.8, Drer\zmp:0000001088, Drer\si:dkey-78l4.2" - "Cele\try-1, Cele\svh-1" - "Mmus\Mcpt9, Mmus\Egfbp2, Mmus\Klk5, Mmus\Prss53, Mmus\Klk13, Mmus\Klk15, Mmus\Klk1b9, Mmus\Ctsg, Mmus\Klk1b4, Mmus\Klk4, Mmus\Gzmk, Mmus\Klk1b21, Mmus\Gzmf, Mmus\Gzmd, Mmus\Prtn3, Mmus\Klk1b16, Mmus\Klk1b5, Mmus\Gzma, Mmus\Klk1b8, Mmus\Klk1b11, Mmus\Cma1, Mmus\Klk1b24, Mmus\Klk1, Mmus\Klk8, Mmus\Mcpt4, Mmus\Cela1, Mmus\Gzme, Mmus\Gzmc, Mmus\Klk1b26, Mmus\Mcpt1, Mmus\Elane, Mmus\Klk1b27, Mmus\Cma2, Mmus\Klk1b1, Mmus\Klk11, Mmus\Gzmn, Mmus\Klk1b22, Mmus\Prss36, Mmus\Klk7, Mmus\Klk14, Mmus\Klk12, Mmus\Mcpt2, Mmus\Klk10, Mmus\Klk6, Mmus\Klk1b3, Mmus\Klk9, Mmus\Gzmg, Mmus\Mcpt8, Mmus\Gzmm" "Hsap\PROC, Hsap\KLK4, Hsap\KLK3, Hsap\KLK14, Hsap\PRSS36, Hsap\KLK13, Hsap\PRSS57, Hsap\GZMH, Hsap\AZU1, Hsap\PRTN3, Hsap\GZMB, Hsap\KLK12, Hsap\KLK1, Hsap\CTSG, Hsap\KLK2, Hsap\KLK6, Hsap\KLK5, Hsap\KLK9, Hsap\CFD, Hsap\ELANE, Hsap\PRSS53, Hsap\KLK11, Hsap\GZMK, Hsap\KLK15, Hsap\GZMA, Hsap\KLK10, Hsap\CMA1, Hsap\GZMM, Hsap\KLK7, Hsap\KLK8" FBgn0026061 Mipp1 Multiple inositol polyphosphate phosphatase 1 http://flybase.org/reports/FBgn0026061 - protein_coding_gene inositol phosphate phosphatase activity ; GO:0052745 | inferred from direct assay bisphosphoglycerate 3-phosphatase activity ; GO:0034417 | inferred from sequence or structural similarity with HGNC:7102 acid phosphatase activity ; GO:0003993 | inferred from biological aspect of ancestor with PANTHER:PTN000469220 positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:7102 open tracheal system development ; GO:0007424 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay anchored component of external side of plasma membrane ; GO:0031362 | inferred from direct assay filopodium ; GO:0030175 | inferred from direct assay extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:7102 "CK2082, CG4123, Mipp1, mipp1" "IPR000560:Histidine phosphatase superfamily, clade-2, IPR016274:Histidine acid phosphatase, eukaryotic, IPR029033:Histidine phosphatase superfamily" CG4123 11-Aug-17 DroID_v2017_08 "Drer\minpp1a, Drer\minpp1b" "Scer\PHO11, Scer\DIA3, Scer\PHO12, Scer\PHO3, Scer\PHO5" - Xtro\minpp1 Mmus\Minpp1 Hsap\MINPP1 "viable,fertile" FBgn0032643 GCS2beta Glucosidase 2 beta subunit http://flybase.org/reports/FBgn0032643 protein_coding_gene - N-glycan processing ; GO:0006491 | inferred from electronic annotation with InterPro:IPR026874 lateral inhibition ; GO:0046331 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay "CG6453, Q9VJD1_DROME, GCS2beta" "IPR009011:Mannose-6-phosphate receptor binding domain, IPR018247:EF-Hand 1, calcium-binding site, IPR026874:Glucosidase 2 subunit beta, IPR028146:Glucosidase II beta subunit, N-terminal, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR011992:EF-hand domain pair" CG6453 11-Aug-17 DroID_v2017_08 "Drer\prkcsh, Drer\gnptg" Scer\GTB1 Cele\ZK1307.8 "Xtro\prkcsh, Xtro\gnptg" "Mmus\Gnptg, Mmus\Prkcsh" "Hsap\PRKCSH, Hsap\GNPTG" "viable,visible" "chaeta,supernumerary,trichogen cell,wing" DRSC02960 E -0.944504667 0.935699426 0.505663451 1.597077309 0.845439419 0.278840255 FBgn0027563 CG9631 - http://flybase.org/reports/FBgn0027563 - protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR018114 endopeptidase activity ; GO:0004175 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP60, BcDNA:GH08420, CG9631" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR031986:Serine protease gd, N-terminal domain, IPR033116:Serine proteases, trypsin family, serine active site" CG9631 11-Aug-17 DroID_v2017_08 "Drer\f9b, Drer\masp1, Drer\pamr1" - "Cele\try-5, Cele\svh-1" - - - viable FBgn0051370 CG31370 - http://flybase.org/reports/FBgn0051370 protein_coding_gene - - - "CG13660, CG31370" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31370 11-Aug-17 DroID_v2017_08 - - "Cele\E02C12.6, Cele\D1044.1, Cele\E02C12.10, Cele\F56A4.5, Cele\F59B1.10, Cele\F59B1.8, Cele\Y45G12C.4, Cele\nhr-246, Cele\F49C12.7, Cele\H06H21.8, Cele\T16G1.5, Cele\H37A05.2, Cele\dhs-27, Cele\Y11D7A.8, Cele\E02C12.8, Cele\C29F7.1, Cele\T16G1.6, Cele\C29F7.2" - - - "viable,fertile" FBgn0035229 pns pinstripe http://flybase.org/reports/FBgn0035229 protein_coding_gene calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence or structural similarity with HGNC:29044 regulation of Rab protein signal transduction ; GO:0032483 | inferred from sequence or structural similarity with HGNC:29044 detection of mechanical stimulus ; GO:0050982 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000093539 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:29044 "CG7852, pns" "IPR001024:PLAT/LH2 domain, IPR001194:DENN domain, IPR004012:RUN domain, IPR005112:dDENN domain, IPR005113:uDENN domain" CG7852 11-Aug-17 DroID_v2017_08 "Drer\dennd4c, Drer\dennd5b, Drer\sbf1, Drer\dennd5a, Drer\dennd4a" - "Cele\lst-6, Cele\denn-4" "Xtro\dennd5b, Xtro\sbf1, Xtro\dennd5a" "Mmus\Sbf1, Mmus\Dennd2c, Mmus\Dennd5a, Mmus\Dennd5b, Mmus\Dennd4c, Mmus\Dennd4a" "Hsap\DENND5A, Hsap\DENND5B, Hsap\DENND2C, Hsap\DENND4C, Hsap\SBF1" viable FBgn0027575 GABA-B-R2 metabotropic GABA-B receptor subtype 2 http://flybase.org/reports/FBgn0027575 "FBgn0046522, FBgn0046523" protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with GABA-B-R1 G-protein coupled GABA receptor activity ; GO:0004965 | inferred from sequence or structural similarity G-protein coupled GABA receptor activity ; GO:0004965 | contributes_to inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity negative regulation of insulin secretion ; GO:0046676 | inferred from mutant phenotype negative regulation of synaptic vesicle fusion to presynaptic membrane ; GO:0031631 | inferred from direct assay gamma-aminobutyric acid signaling pathway ; GO:0007214 | inferred from direct assay negative regulation of adenylate cyclase activity ; GO:0007194 | inferred from direct assay cellular response to mechanical stimulus ; GO:0071260 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from direct assay G-protein coupled receptor heterodimeric complex ; GO:0038039 | inferred from physical interaction with GABA-B-R1 integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "GB2, GH07312, D-Gaba2, D-GABA[[B]]R2, CG6706, GABA[[B]]R2, BcDNA:GH07312, anon-WO0170980.59, anon-WO0170980.58, GABA-B-R2, GABA[[B]]-R2, GABA-[[B]]R2, GBR, GABABR2, GABA B R2, GABA-BR2" "IPR017978:GPCR family 3, C-terminal, IPR017979:GPCR, family 3, conserved site, IPR001828:Receptor, ligand binding region, IPR002455:GPCR family 3, GABA-B receptor, IPR002456:GPCR family 3, gamma-aminobutyric acid receptor, type B1, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR028082:Periplasmic binding protein-like I, IPR002457:GPCR family 3, gamma-aminobutyric acid receptor, type B2" CG6706 11-Aug-17 DroID_v2017_08 "Drer\gabbr1a, Drer\gpr156, Drer\gabbr2" - Cele\gbb-2 "Xtro\gabbr1, Xtro\gabbr2" "Mmus\Gabbr2, Mmus\Gpr156, Mmus\Gabbr1" "Hsap\GABBR2, Hsap\GABBR1, Hsap\GPR156" "short lived,nutrition conditional,neurophysiology defective,courtship behavior defective,viable,circadian rhythm defective" FBgn0070048 3L-211-27 3L-211-27 http://flybase.org/reports/FBgn0070048 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3L-211-27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0002125 l(2)II032 lethal (2) II032 http://flybase.org/reports/FBgn0002125 - gene - - - l(2)II032 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" embryonic head FBgn0028151 l(3)S044422 lethal (3) S044422 http://flybase.org/reports/FBgn0028151 gene - - - "0444/22, l(3)S044422" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0001393 l(1)2Ce lethal (1) 2Ce http://flybase.org/reports/FBgn0001393 - gene - - - "l(1)GF316, l(1)2Ce" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,polyphasic,lethal - all die before end of larval stage,some die during larval stage" FBgn0015585 Acp63F Accessory gland protein 63F http://flybase.org/reports/FBgn0015585 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "Acp63F, Acp63f, CG10852, Acp63F/64A, acp63F, Acp63" - CG10852 11-Aug-17 DroID_v2017_08 - - - - - - adult stage | male " male accessory gland

, male accessory gland main cell

" viable FBgn0013433 beat-Ia beaten path Ia http://flybase.org/reports/FBgn0013433 FBgn0024596 protein_coding_gene molecular_function ; GO:0003674 | no biological data available Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype defasciculation of motor neuron axon ; GO:0007415 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with SoxN heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from genetic interaction with beat-Ic axon choice point recognition ; GO:0016198 | traceable author statement defasciculation of motor neuron axon ; GO:0007415 | inferred from genetic interaction with beat-Ic extracellular region ; GO:0005576 | inferred from sequence or structural similarity "Beat Ia, beat, beat Ia, CT15567, BG:DS00913.3, tric, l(2)br48, l(2)35Eb, l(2)br47, l(2)35Ea, CG4846, beat-Ia, beat1a, TRiC, CCT, Cct, Beat-Ia" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG4846 11-Aug-17 DroID_v2017_08 "Drer\zgc:172106, Drer\f11r.2, Drer\jam2b" - - Xtro\f11r - Hsap\CADM2 " embryonic stage | stage 12-17 , embryonic stage " " motor neuron

, RP1 neuron

, RP3 neuron

, embryonic central nervous system | presumptive | restricted

, aCC neuron

" embryonic stage "viable,fertile,lethal,recessive" "Bolwig organ,photoreceptor,intersegmental nerve,segmental nerve,abdominal intersegmental nerve,motor neuron,abdominal segmental nerve,A1-7 dorsal acute muscle 1,A1-7 dorsal acute muscle 2,A1-7 dorsal oblique muscle 1,A1-7 dorsal oblique muscle 2,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,distal" FBgn0259532 B0731 - http://flybase.org/reports/FBgn0259532 gene - - - B0731 - - 11-Aug-17 DroID_v2017_08 - - - - - - visible "leg,tarsal segment,arista" FBgn0015462 l(2)37Cn lethal (2) 37Cn http://flybase.org/reports/FBgn0015462 FBgn0013294 gene - - - "l(2)E68, l(2)37Cn" - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,dominant,lethal,recessive" macrochaeta FBgn0017372 l(2)C19 lethal (2) C19 http://flybase.org/reports/FBgn0017372 - gene - - - "C19, l(2)C19" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0039259 CG11781 - http://flybase.org/reports/FBgn0039259 protein_coding_gene - autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000470065 protein folding in endoplasmic reticulum ; GO:0034975 | inferred from biological aspect of ancestor with PANTHER:PTN000470065 endomembrane system ; GO:0012505 | inferred from direct assay ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN000470065 "BcDNA:RE35789, CG11781" "IPR008504:ER membrane protein complex subunit 6, IPR029008:Rab5-interacting protein family" CG11781 11-Aug-17 DroID_v2017_08 Drer\emc6 Scer\EMC6 Cele\emc-6 Xtro\emc6 Mmus\Emc6 Hsap\EMC6 "viable,partially lethal - majority die,some die during pupal stage" FBgn0002967 nrd neural disrupted http://flybase.org/reports/FBgn0002967 - gene molecular_function ; GO:0003674 | no biological data available germ-band shortening ; GO:0007390 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)23Aa, nrd" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive" "embryonic brain,ventral nerve cord,extended germ band embryo,dorsal closure embryo,subesophageal ganglion,embryonic/first instar larval cuticle,embryonic ventral neuromere,cephalopharyngeal skeleton,presumptive embryonic/larval central nervous system,posterior,presumptive embryonic/larval peripheral nervous system" FBgn0028497 CG3530 - http://flybase.org/reports/FBgn0028497 protein_coding_gene "phosphatidylinositol-3-phosphatase activity ; GO:0004438 | inferred from electronic annotation with InterPro:IPR030591 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity ; GO:0052629 | inferred from electronic annotation with InterPro:IPR030591 protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement" regulation of autophagy ; GO:0010506 | inferred from electronic annotation with InterPro:IPR030591 phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from electronic annotation with InterPro:IPR030591 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CG3530, BcDNA, BcDNA:GH04637, CG18093" "IPR000306:FYVE zinc finger, IPR000387:Tyrosine specific protein phosphatases domain, IPR010569:Myotubularin-like phosphatase domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR016130:Protein-tyrosine phosphatase, active site, IPR017455:Zinc finger, FYVE-related, IPR011993:PH domain-like, IPR030564:Myotubularin family, IPR030591:Myotubularin-related protein 8, IPR029021:Protein-tyrosine phosphatase-like, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR003595:Protein-tyrosine phosphatase, catalytic" CG3530 11-Aug-17 DroID_v2017_08 "Drer\mtmr9, Drer\mtmr10, Drer\mtmr1a, Drer\mtmr1b, Drer\mtmr7a, Drer\mtmr12, Drer\zgc:154055, Drer\mtmr8, Drer\mtmr7b, Drer\mtmr6, Drer\mtmr2" Scer\YMR1 "Cele\mtm-1, Cele\mtm-6" "Xtro\mtmr10, Xtro\mtmr7, Xtro\mtmr6, Xtro\mtm1, Xtro\mtmr1, Xtro\mtmr12, Xtro\LOC100216114, Xtro\mtmr9, Xtro\mtmr2, Xtro\asb12.2, Xtro\mtmr8" "Mmus\Mtmr12, Mmus\Mtmr2, Mmus\Mtmr1, Mmus\Mtmr10, Mmus\Mtmr11, Mmus\Mtmr6, Mmus\Mtmr9, Mmus\Mtm1, Mmus\Mtmr7" "Hsap\MTMR12, Hsap\MTMR9, Hsap\MTMR2, Hsap\MTMR1, Hsap\MTMR7, Hsap\MTMR11, Hsap\MTMR8, Hsap\MTMR6, Hsap\MTMR10, Hsap\MTM1" "viable,visible,planar polarity defective" "trichogen cell,mesothoracic tergum" FBgn0041182 Tep2 Thioester-containing protein 2 http://flybase.org/reports/FBgn0041182 protein_coding_gene "endopeptidase inhibitor activity ; GO:0004866 | inferred from electronic annotation with InterPro:IPR001599, InterPro:IPR002890" defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR011626 "Tep2, CG7052, 145971_at, 145970_at, TEP2, T13, CG18589, dTEPII, TEP2mel, TepII, TEP II, Tep II, tepII, Tep 2" "IPR002890:Alpha-2-macroglobulin, N-terminal, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR009048:Alpha-macroglobulin, receptor-binding, IPR011625:Alpha-2-macroglobulin, N-terminal 2, IPR011626:Alpha-macroglobulin complement component, IPR019742:Alpha-2-macroglobulin, conserved site, IPR013783:Immunoglobulin-like fold, IPR019565:Alpha-2-macroglobulin, thiol-ester bond-forming, IPR001599:Alpha-2-macroglobulin" CG7052 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-46g23.2, Drer\si:dkey-8k3.2, Drer\c3a.2, Drer\si:dkey-52d15.2, Drer\cd109, Drer\c3a.1, Drer\c5, Drer\zgc:165518, Drer\a2ml, Drer\c3a.3, Drer\zgc:171426, Drer\c4, Drer\cpamd8, Drer\c3b.2, Drer\c3a.6, Drer\c3a.4, Drer\c3b.1" - Cele\tep-1 "Xtro\ovos2, Xtro\a2ml1, Xtro\c4a, Xtro\c3, Xtro\c5" "Mmus\Cd109, Mmus\Hc, Mmus\BC048546, Mmus\C4b, Mmus\Mug2, Mmus\C3, Mmus\AI182371, Mmus\A2m" "Hsap\CD109, Hsap\C4A, Hsap\C4B_2, Hsap\A2M, Hsap\C5, Hsap\A2ML1, Hsap\C3, Hsap\CPAMD8, Hsap\C4B" viable FBgn0040259 Ugt86Da Ugt86Da http://flybase.org/reports/FBgn0040259 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 UDP-glycosyltransferase activity ; GO:0008194 | inferred from sequence or structural similarity with UniProtKB:P18569 UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with UniProtKB:P18569 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 endomembrane system ; GO:0012505 | inferred from direct assay "CG18578, AC 006491A, GM04645, BEST:GM04645, Ugt86Da, ugt86Da" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG18578 11-Aug-17 DroID_v2017_08 "Drer\ugt5d1, Drer\ugt1ab, Drer\ugt5b1, Drer\ugt2a2, Drer\ugt5a2, Drer\ugt5b4, Drer\ugt2b6, Drer\ugt5c3, Drer\ugt5c1, Drer\ugt2b1, Drer\ugt2b5, Drer\ugt5e1, Drer\ugt1b3, Drer\zgc:172315, Drer\ugt5a4, Drer\ugt5c2, Drer\ugt5b3, Drer\ugt5b6, Drer\ugt2a6, Drer\ugt5a1, Drer\ugt8, Drer\ugt5a5, Drer\ugt2a5, Drer\ugt1b4, Drer\ugt2b3, Drer\ugt5g2, Drer\ugt1b5, Drer\ugt1b7, Drer\ugt5f1, Drer\ugt5g1, Drer\ugt1b2, Drer\ugt5b2" Scer\ATG26 "Cele\ugt-58, Cele\ugt-56, Cele\H23N18.4, Cele\ugt-9, Cele\ugt-21, Cele\ugt-28, Cele\ugt-3, Cele\ugt-42, Cele\C03A7.12, Cele\F10D2.8, Cele\ugt-14, Cele\ugt-57, Cele\C03A7.13, Cele\ugt-33, Cele\ugt-22, Cele\ugt-52, Cele\ugt-8, Cele\ugt-24, Cele\ugt-40, Cele\ugt-29, Cele\ugt-41, Cele\ugt-32, Cele\ugt-44, Cele\ugt-15, Cele\ugt-10, Cele\ugt-54, Cele\ugt-53, Cele\ugt-36, Cele\ugt-1, Cele\K04A8.10, Cele\C23G10.6, Cele\ugt-35, Cele\ugt-51, Cele\F54C1.1, Cele\ugt-34, Cele\ugt-16, Cele\ugt-17, Cele\ugt-47, Cele\ugt-61, Cele\ugt-31, Cele\ugt-45, Cele\ugt-46, Cele\ugt-63, Cele\ugt-43, Cele\ugt-5, Cele\ugt-20, Cele\ugt-65, Cele\ugt-37, Cele\ugt-62, Cele\ugt-26, Cele\ugt-19, Cele\ugt-50, Cele\ugt-11, Cele\ugt-59, Cele\ugt-60, Cele\ugt-2, Cele\ugt-23, Cele\Y43D4A.2, Cele\C55H1.1, Cele\ugt-38, Cele\ugt-6, Cele\ugt-18, Cele\ugt-7, Cele\ugt-12, Cele\ugt-4, Cele\ugt-49, Cele\ugt-13, Cele\ugt-55, Cele\ugt-30, Cele\ugt-25, Cele\ugt-39, Cele\ugt-48, Cele\ugt-27" "Xtro\ugt1a6, Xtro\ugt2b4, Xtro\ugt1a1, Xtro\ugt2a1, Xtro\ugt3a2, Xtro\ugt8" "Mmus\Ugt2a2, Mmus\Ugt2a1, Mmus\Ugt3a1, Mmus\Ugt1a2, Mmus\Ugt2b38, Mmus\Ugt1a1, Mmus\Ugt1a6b, Mmus\Ugt2b36, Mmus\Ugt2b34, Mmus\Ugt1a7c, Mmus\Ugt2b5, Mmus\Ugt2b37, Mmus\Ugt2a3, Mmus\Ugt2b35, Mmus\Ugt2b1, Mmus\Ugt1a10, Mmus\Ugt1a9, Mmus\Ugt8a, Mmus\Ugt1a5, Mmus\Ugt3a2" "Hsap\UGT2B10, Hsap\UGT2B17, Hsap\UGT2B28, Hsap\UGT3A2, Hsap\UGT1A7, Hsap\UGT1A1, Hsap\UGT8, Hsap\UGT1A4, Hsap\UGT2B7, Hsap\UGT1A9, Hsap\UGT2B15, Hsap\UGT1A8, Hsap\UGT1A3, Hsap\UGT2B11, Hsap\UGT3A1, Hsap\UGT2A3, Hsap\UGT1A5, Hsap\UGT2A2, Hsap\UGT1A6, Hsap\UGT1A10, Hsap\UGT2B4" viable FBgn0039705 Atg16 Autophagy-related 16 http://flybase.org/reports/FBgn0039705 protein_coding_gene Atg8 ligase activity ; GO:0019776 | contributes_to inferred from sequence or structural similarity with SGD:S000004769 protein lipidation ; GO:0006497 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype macroautophagy ; GO:0016236 | inferred from sequence or structural similarity with SGD:S000004769 glycophagy ; GO:0061723 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000459084 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype Atg12-Atg5-Atg16 complex ; GO:0034274 | inferred from sequence or structural similarity with SGD:S000004769 autophagosome membrane ; GO:0000421 | inferred from biological aspect of ancestor with PANTHER:PTN000459084 "Atg16, CG18683, CG15513, CG18040, CG31033, atg16" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013923:Autophagy-related protein 16, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like" CG31033 11-Aug-17 DroID_v2017_08 "Drer\atg16l2, Drer\atg16l1, Drer\si:ch1073-143l10.2" "Scer\MDV1, Scer\UTP13, Scer\CAF4" "Cele\atg-16.2, Cele\atg-16.1" Xtro\atg16l1 "Mmus\Atg16l2, Mmus\Atg16l1" "Hsap\ATG16L2, Hsap\ATG16L1" viable "embryonic/larval fat body,somatic clone | third instar larval stage" FBgn0031818 CG9536 - http://flybase.org/reports/FBgn0031818 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR022764 molecular_function ; GO:0003674 | no biological data available "retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000332711 protein glycosylation ; GO:0006486 | inferred from sequence or structural similarity with HGNC:30055" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013861 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:30055 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000332711 CG9536 "IPR013861:Transmembrane protein DUF1751, eukaryotic, IPR022764:Peptidase S54, rhomboid domain" CG9536 11-Aug-17 DroID_v2017_08 Drer\tmem115 Scer\YOL107W Cele\F11A10.6 Xtro\tmem115 Mmus\Tmem115 Hsap\TMEM115 "viable,fertile,female fertile" FBgn0025394 inc insomniac http://flybase.org/reports/FBgn0025394 "FBgn0040897, FBgn0052810" protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from direct assay myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A "protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 sleep ; GO:0030431 | inferred from mutant phenotype regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype" - "EG:196F3.2, CG14783, CG14784, CG32810, inc, ins, INC" "IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR011333:SKP1/BTB/POZ domain" CG32810 11-Aug-17 DroID_v2017_08 "Drer\kctd2, Drer\kctd17, Drer\LOC101886650, Drer\kctd5a" - "Cele\inso-1, Cele\H42K12.3, Cele\ZC239.15" "Xtro\kctd2, Xtro\kctd5" "Mmus\Kctd17, Mmus\Kctd5, Mmus\Kctd2" "Hsap\KCTD17, Hsap\KCTD5, Hsap\KCTD2" "sleep defective,recessive,short lived,viable,fertile,neuroanatomy defective,circadian rhythm defective,visible,RU486 conditional" "mushroom body alpha-lobe,mushroom body beta-lobe,trichogen cell" DRSC28898 K 0.666509793 0.464407973 0.319747784 -0.643275321 1.564706349 1.614933236 FBgn0030943 CG6540 - http://flybase.org/reports/FBgn0030943 protein_coding_gene nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with SGD:S000002246 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000488224 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000488224 phospholipid binding ; GO:0005543 | inferred from biological aspect of ancestor with PANTHER:PTN000488224 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000488224 nuclear pore organization ; GO:0006999 | inferred from biological aspect of ancestor with PANTHER:PTN000488224 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype nuclear pore organization ; GO:0006999 | inferred from sequence or structural similarity with SGD:S000002246 NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN000488224" nuclear membrane ; GO:0031965 | inferred from electronic annotation with InterPro:IPR017389 nuclear pore nuclear basket ; GO:0044615 | inferred from biological aspect of ancestor with PANTHER:PTN000488224 nuclear pore central transport channel ; GO:0044613 | inferred from sequence or structural similarity with SGD:S000002246 nuclear pore central transport channel ; GO:0044613 | inferred from biological aspect of ancestor with PANTHER:PTN000488224 lipid particle ; GO:0005811 | inferred from direct assay "CG6540, Nup35" "IPR007846:RNA-recognition motif (RRM) Nup35-type domain, IPR017389:Nucleoporin, NUP53, IPR000504:RNA recognition motif domain" CG6540 11-Aug-17 DroID_v2017_08 Drer\nup35 "Scer\ASM4, Scer\NUP53" Cele\npp-19 Xtro\nup35 Mmus\Nup35 Hsap\NUP35 viable FBgn0053013 CR33013 - http://flybase.org/reports/FBgn0053013 pseudogene_attribute - - - "CG30041, CG13161, CG33013, CR33013" - CR33013 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC06286 K 0.047187026 -0.401063606 0.193932537 -0.042691498 1.728410997 0.740531105 FBgn0031909 CG5181 - http://flybase.org/reports/FBgn0031909 protein_coding_gene single-stranded DNA binding ; GO:0003697 | inferred from sequence or structural similarity with HGNC:28412 mitotic cell cycle checkpoint ; GO:0007093 | inferred from electronic annotation with InterPro:IPR033550 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with HGNC:28412 SOSS complex ; GO:0070876 | inferred from electronic annotation with InterPro:IPR033550 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:28412 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:28412 "CG5181, CC24" "IPR012340:Nucleic acid-binding, OB-fold, IPR033550:SOSS complex subunit B2" CG5181 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-249d8.1, Drer\si:ch73-190f16.2, Drer\nabp1a, Drer\nabp1b" - Cele\C06G3.8 Xtro\nabp2 "Mmus\Nabp1, Mmus\Nabp2" "Hsap\NABP2, Hsap\NABP1" "viable,fertile" FBgn0263112 Mitf Mitf http://flybase.org/reports/FBgn0263112 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay cellular response to starvation ; GO:0009267 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype lysosome organization ; GO:0007040 | inferred from mutant phenotype positive regulation of autophagosome maturation ; GO:1901098 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype lipid catabolic process ; GO:0016042 | inferred from mutant phenotype" - "CG17469, Mitf, CG43369, CG40476, MITF, dMitf, CG41130, MitF, TFEB" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR031867:MiT/TFE transcription factors, N-terminal" CG43369 11-Aug-17 DroID_v2017_08 "Drer\srebf1, Drer\usf2, Drer\srebf2, Drer\tfe3a, Drer\usf1, Drer\mitfb, Drer\mitfa, Drer\tfeb, Drer\tfe3b, Drer\usf1l, Drer\tfec" "Scer\CBF1, Scer\RTG3, Scer\HMS1, Scer\RTG1" "Cele\hlh-30, Cele\sbp-1" "Xtro\tfec, Xtro\tfe3, Xtro\srebf2, Xtro\tfeb, Xtro\mitf" "Mmus\Tfec, Mmus\Srebf2, Mmus\Srebf1, Mmus\Tfeb, Mmus\Tfe3, Mmus\Mitf, Mmus\Usf1" "Hsap\TFE3, Hsap\TFEC, Hsap\TFEB, Hsap\USF2, Hsap\USF1, Hsap\SREBF2, Hsap\MITF" FBgn0040212 Dhap-at Dihydroxyacetone phosphate acyltransferase http://flybase.org/reports/FBgn0040212 protein_coding_gene glycerone-phosphate O-acyltransferase activity ; GO:0016287 | inferred from sequence or structural similarity with HGNC:4416 ether lipid biosynthetic process ; GO:0008611 | inferred from sequence or structural similarity with HGNC:4416 peroxisome ; GO:0005777 | inferred from sequence model peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:4416 "CG4625, DHAP-AT, GPAT, 8-1, Gpat, Dhap-at" "IPR002123:Phospholipid/glycerol acyltransferase, IPR028353:Dihydroxyacetone phosphate acyltransferase, IPR022284:Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase" CG4625 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-21k16.5, Drer\gnpat" - Cele\acl-7 "Xtro\LOC100494829, Xtro\gnpat" Mmus\Gnpat Hsap\GNPAT viable FBgn0042175 CG18858 - http://flybase.org/reports/FBgn0042175 protein_coding_gene O-acyltransferase activity ; GO:0008374 | inferred from electronic annotation with InterPro:IPR003386 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR003386 - "38C.53, CG18858" "IPR003386:Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase, IPR029058:Alpha/Beta hydrolase fold" CG18858 11-Aug-17 DroID_v2017_08 "Drer\lcat, Drer\pla2g15" "Scer\TGL2, Scer\LRO1, Scer\YJR098C" Cele\M05B5.4 "Xtro\lcat, Xtro\pla2g15" "Mmus\Lcat, Mmus\Pla2g15" "Hsap\PLA2G15, Hsap\LCAT" FBgn0260964 Vmat Vesicular monoamine transporter http://flybase.org/reports/FBgn0260964 protein_coding_gene drug transmembrane transporter activity ; GO:0015238 | inferred from electronic annotation with InterPro:IPR004734 serotonin transmembrane transporter activity ; GO:0015222 | inferred from biological aspect of ancestor with PANTHER:PTN000607052 monoamine transmembrane transporter activity ; GO:0008504 | inferred from direct assay synaptic vesicle amine transmembrane transporter activity ; GO:0005430 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 drug transport ; GO:0015893 | inferred from electronic annotation with InterPro:IPR004734 aminergic neurotransmitter loading into synaptic vesicle ; GO:0015842 | inferred from direct assay positive regulation of dopaminergic neuron differentiation ; GO:1904340 | inferred from mutant phenotype dopamine transport ; GO:0015872 | inferred from mutant phenotype histamine transport ; GO:0051608 | inferred from mutant phenotype response to rotenone ; GO:1904647 | inferred from mutant phenotype monoamine transport ; GO:0015844 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001519445 "CG6119, DVMAT, VMAT, Vmat, dVMAT, CG6139, CG33528, l(2)SH0459, l(2)SH2 0459, DVMAT-A, DVMAT-B, vmat" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain, IPR004734:Multidrug resistance protein" CG33528 11-Aug-17 DroID_v2017_08 "Drer\slc18a1, Drer\slc18a2, Drer\slc18a3a, Drer\slc18a3b" - "Cele\cat-1, Cele\unc-17, Cele\F27D9.2" "Xtro\slc18a1, Xtro\slc18a3" "Mmus\Slc18a3, Mmus\Slc18a2, Mmus\Slc18a1" "Hsap\SLC18A3, Hsap\SLC18A2, Hsap\SLC18A1" FBgn0032796 CG10188 - http://flybase.org/reports/FBgn0032796 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with RhoGEF2 positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with RhoGEF2 cellular_component ; GO:0005575 | no biological data available CG10188 "IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG10188 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-240h12.3, Drer\arhgef18b, Drer\arhgef18a, Drer\arhgef1a, Drer\akap13, Drer\arhgef28, Drer\arhgef2, Drer\wu:fi15d04" "Scer\ROM2, Scer\ROM1, Scer\TUS1" Cele\rhgf-1 "Xtro\akap13, Xtro\arhgef28" "Mmus\Arhgef2, Mmus\Akap13, Mmus\Arhgef28, Mmus\Arhgef18" "Hsap\AKAP13, Hsap\ARHGEF28, Hsap\ARHGEF18, Hsap\ARHGEF2" viable FBgn0250816 AGO3 Argonaute 3 http://flybase.org/reports/FBgn0250816 protein_coding_gene piRNA binding ; GO:0034584 | inferred from direct assay RNA binding ; GO:0003723 | inferred from direct assay positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from mutant phenotype negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype posttranscriptional gene silencing by RNA ; GO:0035194 | inferred from mutant phenotype P granule ; GO:0043186 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "ago3, Ago3, Ago-3, AGO3, CG40300, dAgo3, BEST:LD15785" "IPR003100:PAZ domain, IPR003165:Piwi domain, IPR012337:Ribonuclease H-like domain" CG40300 11-Aug-17 DroID_v2017_08 "Drer\piwil1, Drer\LOC567622, Drer\piwil2, Drer\ago1, Drer\ago2, Drer\ago3b" - "Cele\prg-1, Cele\prg-2, Cele\alg-1, Cele\alg-3, Cele\hpo-24, Cele\rde-1" "Xtro\ago2, Xtro\piwil2, Xtro\ago4, Xtro\piwil4, Xtro\piwil3, Xtro\ago3" "Mmus\Ago2, Mmus\Ago3, Mmus\Piwil4, Mmus\Ago4, Mmus\Ago1, Mmus\Piwil1, Mmus\Piwil2" "Hsap\AGO1, Hsap\AGO2, Hsap\PIWIL3, Hsap\AGO4, Hsap\AGO3, Hsap\PIWIL2, Hsap\PIWIL1, Hsap\PIWIL4" "viable,female sterile,male sterile,partially" "dorsal appendage,maternal effect,egg" FBgn0039748 CG15529 - http://flybase.org/reports/FBgn0039748 protein_coding_gene - intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN001019935 immune response ; GO:0006955 | inferred from biological aspect of ancestor with PANTHER:PTN001019935 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN001019935 - CG15529 IPR000980:SH2 domain CG15529 11-Aug-17 DroID_v2017_08 "Drer\blnk, Drer\lcp2b, Drer\si:dkeyp-117b11.1, Drer\lcp2a" - Cele\Y37D8A.4 Xtro\blnk "Mmus\Sh2d6, Mmus\Lcp2, Mmus\Blnk, Mmus\Clnk" "Hsap\SH2D6, Hsap\CLNK, Hsap\LCP2, Hsap\BLNK" viable FBgn0053510 CG33510 - http://flybase.org/reports/FBgn0053510 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14398, CG33510" "IPR011009:Protein kinase-like domain, IPR004119:Protein of unknown function DUF227, IPR015897:CHK kinase-like" CG33510 11-Aug-17 DroID_v2017_08 - - "Cele\E02C12.6, Cele\Y45G12C.4, Cele\D1044.1, Cele\F48G7.12, Cele\E02C12.10, Cele\T16G1.3, Cele\E02C12.8, Cele\dhs-27, Cele\T16G1.7, Cele\H37A05.2, Cele\F49C12.7, Cele\F59B1.10, Cele\T16G1.6, Cele\F59B1.8, Cele\F20D6.5, Cele\C29F7.2, Cele\C18B10.6, Cele\E02C12.9, Cele\C29F7.1, Cele\F58B4.5, Cele\T16G1.4, Cele\Y11D7A.8, Cele\F56A4.5, Cele\T16G1.5, Cele\nhr-246" - - - FBgn0034590 Magi Magi http://flybase.org/reports/FBgn0034590 protein_coding_gene Ral GTPase binding ; GO:0017160 | inferred from physical interaction with Rala adherens junction organization ; GO:0034332 | inferred from mutant phenotype apicolateral plasma membrane ; GO:0016327 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay "ima, Ima, D-MAGI, CG4117, CG15656, CG30388, Magi, magi" "IPR001202:WW domain, IPR001478:PDZ domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG30388 11-Aug-17 DroID_v2017_08 "Drer\magi2a, Drer\grip2b, Drer\LOC556872, Drer\grip2a, Drer\grip1, Drer\inadl, Drer\LOC564220, Drer\magi3a, Drer\magi1b, Drer\magi2b, Drer\magi1a, Drer\magixa" - "Cele\C01B7.5, Cele\magi-1" "Xtro\magi1, Xtro\magi3, Xtro\magi2" "Mmus\Grip2, Mmus\Magix, Mmus\Grip1, Mmus\Magi2, Mmus\Magi3, Mmus\Magi1, Mmus\Mpdz" "Hsap\MAGI2, Hsap\MPDZ, Hsap\GRIP2, Hsap\PTPN13, Hsap\MAGIX, Hsap\GRIP1, Hsap\MAGI1, Hsap\MAGI3" "visible,wild-type,viable" "ommatidium,eye,scutellar bristle,supernumerary" FBgn0261862 whd withered http://flybase.org/reports/FBgn0261862 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR000542" response to metal ion ; GO:0010038 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay "whd, CPTI, CG12891, gh27794, BEST:GH27794, CPT1, Cpt1, dCPT1" "IPR000542:Acyltransferase ChoActase/COT/CPT, IPR032476:Carnitine O-palmitoyltransferase, N-terminal" CG12891 11-Aug-17 DroID_v2017_08 "Drer\zgc:154046, Drer\cratb, Drer\cpt1cb, Drer\LOC100333227, Drer\cpt1aa, Drer\si:ch211-256m1.8, Drer\chata, Drer\cpt1b, Drer\LOC101884918, Drer\cpt1ab, Drer\crata" "Scer\YAT1, Scer\CAT2, Scer\YAT2" "Cele\cpt-1, Cele\cpt-4, Cele\cpt-6, Cele\cpt-3, Cele\W03F9.4" "Xtro\crat.1, Xtro\LOC100490391, Xtro\crat.2, Xtro\cpt1b, Xtro\chat" "Mmus\Chat, Mmus\Cpt1c, Mmus\Cpt1a, Mmus\Cpt1b, Mmus\Crat" "Hsap\CHAT, Hsap\CPT1A, Hsap\CHKB, Hsap\CPT1B, Hsap\CPT1C, Hsap\CRAT" FBgn0036255 Atg12 Autophagy-related 12 http://flybase.org/reports/FBgn0036255 protein_coding_gene Atg8 ligase activity ; GO:0019776 | contributes_to inferred from sequence or structural similarity with SGD:S000000421 Atg8 ligase activity ; GO:0019776 | inferred from biological aspect of ancestor with PANTHER:PTN000333039 protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000000421 mitophagy ; GO:0000422 | inferred from biological aspect of ancestor with PANTHER:PTN000333039 macroautophagy ; GO:0016236 | inferred from mutant phenotype C-terminal protein lipidation ; GO:0006501 | inferred from biological aspect of ancestor with PANTHER:PTN000333039 autophagic cell death ; GO:0048102 | inferred from expression pattern glycophagy ; GO:0061723 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000333039 nucleophagy ; GO:0044804 | inferred from biological aspect of ancestor with PANTHER:PTN000333039 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from sequence or structural similarity with SGD:S000000421 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern Atg12-Atg5-Atg16 complex ; GO:0034274 | inferred from sequence or structural similarity with SGD:S000000421 pre-autophagosomal structure membrane ; GO:0034045 | inferred from biological aspect of ancestor with PANTHER:PTN000333039 Atg12-Atg5-Atg16 complex ; GO:0034274 | inferred from biological aspect of ancestor with PANTHER:PTN000333039 "Atg12, CG10861, atg12, ATG12" "IPR007242:Ubiquitin-like protein Atg12, IPR029071:Ubiquitin-related domain" CG10861 11-Aug-17 DroID_v2017_08 Drer\atg12 Scer\ATG12 Cele\lgg-3 Xtro\atg12 Mmus\Atg12 Hsap\ATG12 "immune response defective,RU486 conditional,locomotor behavior defective,increased cell death,chemical conditional,viable" "embryonic/larval salivary gland,fat body,somatic clone,calorie restriction conditional,autophagic vacuole | somatic clone | calorie restriction conditional,intestinal stem cell,chemical conditional" DRSC09803 K -0.924716153 0.310048173 -0.911834318 0.642875924 -0.757104185 -2.313548335 FBgn0051988 CG31988 - http://flybase.org/reports/FBgn0051988 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 - - "CG17401, bs21c01.y1, anon-WO0140519.26, CG31988" "IPR001781:Zinc finger, LIM-type" CG31988 11-Aug-17 DroID_v2017_08 "Drer\pxnb, Drer\pdlim3a, Drer\zyx, Drer\pdlim3b, Drer\pdlim4, Drer\fhl3b, Drer\fhl3a, Drer\si:rp71-15d4.1, Drer\pdlim5b, Drer\pdlim5a, Drer\pxna, Drer\pdlim2, Drer\pdlim1" "Scer\LRG1, Scer\PXL1" "Cele\Y1A5A.1, Cele\alp-1" "Xtro\fhl5, Xtro\fhl2, Xtro\pdlim7, Xtro\pdlim4, Xtro\pxn, Xtro\pdlim3, Xtro\pdlim5, Xtro\pdlim1, Xtro\tgfb1i1, Xtro\fhl3" "Mmus\Pdlim1, Mmus\Pdlim4, Mmus\Fhl1, Mmus\Lpxn, Mmus\Pdlim3, Mmus\Fhl5, Mmus\Pxn, Mmus\Pdlim2, Mmus\Ldb3, Mmus\Pdlim5, Mmus\Tgfb1i1, Mmus\Pdlim7, Mmus\Fhl2, Mmus\Fhl4, Mmus\Fhl3" "Hsap\FHL2, Hsap\PDLIM1, Hsap\PDLIM2, Hsap\FHL1, Hsap\PDLIM5, Hsap\LPXN, Hsap\FHL3, Hsap\FHL5, Hsap\TGFB1I1, Hsap\PDLIM7, Hsap\PDLIM4, Hsap\LDB3, Hsap\PXN, Hsap\PDLIM3" viable FBgn0039778 Jon99Fi Jonah 99Fi http://flybase.org/reports/FBgn0039778 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "CG18030, Jon99F, SPH181, Jon99Fi" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG18030 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Cela3b, Mmus\Cela3a, Mmus\Cela1, Mmus\Cela2a, Mmus\Ctrb1, Mmus\Ctrc, Mmus\Ctrl" - FBgn0029839 CG4660 - http://flybase.org/reports/FBgn0029839 protein_coding_gene - - - "BcDNA:RH58440, CG4660" IPR029069:HotDog domain CG4660 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-52e5.2, Drer\si:ch73-52e5.1" Scer\YBR096W - Xtro\them6 Mmus\Them6 Hsap\THEM6 FBgn0035165 CG13887 - http://flybase.org/reports/FBgn0035165 protein_coding_gene - intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR008417 protein localization to endoplasmic reticulum exit site ; GO:0070973 | inferred from biological aspect of ancestor with PANTHER:PTN000294723 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000294723 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008417 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000294723 endomembrane system ; GO:0012505 | inferred from direct assay CG13887 IPR008417:B-cell receptor-associated protein 29/31 CG13887 11-Aug-17 DroID_v2017_08 "Drer\bcap29, Drer\bcap31" "Scer\YET2, Scer\YET3, Scer\YET1" Cele\Y54G2A.18 "Xtro\bcap31, Xtro\bcap29" "Mmus\Bcap29, Mmus\Bcap31" "Hsap\BCAP29, Hsap\BCAP31" viable FBgn0038421 CG17931 - http://flybase.org/reports/FBgn0038421 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytosol ; GO:0005829 | inferred from direct assay "BcDNA:AT19233, CG17931" IPR007513:Uncharacterised protein family SERF CG17931 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-39k3.2, Drer\serf2" Scer\YDL085C-A Cele\moag-4 Xtro\serf2 "Mmus\Serf2, Mmus\Serf1, Mmus\Hypk" "Hsap\SERF1A, Hsap\HYPK, Hsap\SERF2, Hsap\SERF1B" "viable,fertile" FBgn0037607 CG8036 - http://flybase.org/reports/FBgn0037607 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR009014 regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "anon-WO0118547.344, CG8036" "IPR005474:Transketolase, N-terminal, IPR005475:Transketolase-like, pyrimidine-binding domain, IPR009014:Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II, IPR020826:Transketolase binding site, IPR029061:Thiamin diphosphate-binding fold, IPR033248:Transketolase, C-terminal domain" CG8036 11-Aug-17 DroID_v2017_08 "Drer\tkta, Drer\tktb" "Scer\TKL1, Scer\TKL2" Cele\tkt-1 "Xtro\tkt, Xtro\tktl2" "Mmus\Tktl1, Mmus\Tktl2, Mmus\Tkt" "Hsap\TKT, Hsap\TKTL2, Hsap\TKTL1" "lethal,viable,fertile" DRSC16366 EK 0.32016666 -0.176214142 -1.544800852 0.410189454 0.041681434 1.779288202 FBgn0034184 CG9646 - http://flybase.org/reports/FBgn0034184 protein_coding_gene - - - CG9646 IPR019141:Protein of unknown function DUF2045 CG9646 11-Aug-17 DroID_v2017_08 Drer\zgc:172139 - "Cele\spon-1, Cele\C16E9.2" Xtro\kiaa0930 Mmus\5031439G07Rik Hsap\KIAA0930 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0037592 CG11737 - http://flybase.org/reports/FBgn0037592 protein_coding_gene molecular_function ; GO:0003674 | no biological data available peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with RGD:1309948 peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000279123 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with RGD:1309948 CG11737 "IPR026749:Transmembrane protein 135, IPR031926:Transmembrane protein 135, N-terminal domain" CG11737 11-Aug-17 DroID_v2017_08 Drer\tmem135 - Cele\tmem-135 Xtro\tmem135 Mmus\Tmem135 Hsap\TMEM135 "viable,fertile" FBgn0044028 Notum Notum http://flybase.org/reports/FBgn0044028 protein_coding_gene palmitoleyl hydrolase activity ; GO:1990699 | inferred from biological aspect of ancestor with PANTHER:PTN001090191 phospholipase activity ; GO:0004620 | NOT inferred from direct assay palmitoleyl hydrolase activity ; GO:1990699 | inferred from sequence or structural similarity with UniProtKB:Q6P988 deacetylase activity ; GO:0019213 | NOT inferred from direct assay negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with Sulf1 GPI anchor release ; GO:0006507 | NOT inferred from direct assay ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of compound eye pigmentation ; GO:0048076 | inferred from mutant phenotype protein depalmitoleylation ; GO:1990697 | inferred from biological aspect of ancestor with PANTHER:PTN001090191 protein depalmitoleylation ; GO:1990697 | inferred from sequence or structural similarity with UniProtKB:Q6P988 negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from direct assay negative regulation of Wnt signaling pathway ; GO:0030178 | non-traceable author statement Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from biological aspect of ancestor with PANTHER:PTN001090191 wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with dally proteoglycan metabolic process ; GO:0006029 | non-traceable author statement GPI anchor release ; GO:0006507 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "Not, wf, CG13076, l(3)72CDf, l(3)72Da, anon-WO03062410.8, anon-WO03062410.10, anon-WO0118547.482, Notum, notum, ntm, Nt, Wf" "IPR004963:Pectinacetylesterase/NOTUM, IPR029058:Alpha/Beta hydrolase fold" CG13076 11-Aug-17 DroID_v2017_08 "Drer\notum1a, Drer\notum2, Drer\notum1b" - - Xtro\notum Mmus\Notum Hsap\NOTUM " embryonic stage | extended germ band , larval stage | third instar " " organism | segmentally repeated

, dorsal mesothoracic disc | dorsal/ventral compartment boundary

" "visible,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,somatic clone,increased cell death,lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,cell non-autonomous,viable" "wing,wing margin bristle,mesothoracic tergum,adult thorax,dorsal,ectopic,embryonic/first instar larval cuticle,denticle,leg,wing disc,mechanosensory ventral triple row bristle,somatic clone,external sensory organ precursor cell,denticle belt,rescuable maternal effect,eye,pigment cell,supernumerary,abdominal sternite bristle,dorsocentral bristle,wing sensillum,cell non-autonomous,sensory mother cell,medial triple row,denticle row 1,wing margin,mechanosensory chaeta,taste bristle,dorsal compartment,dorsal row,posterior" FBgn0014948 btl::tor btl::tor http://flybase.org/reports/FBgn0014948 - engineered_fusion_gene - - - btl::tor - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,increased cell number,somatic clone" "wing,wing vein,embryonic/larval tracheal system,dorsal air sac primordium,somatic clone" FBgn0062589 Mod(var)1641 Mod(var)1641 http://flybase.org/reports/FBgn0062589 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1641, Mod(var)1641" - - 11-Aug-17 DroID_v2017_08 - - - - - - "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0015974 l(2)PC4-51 lethal (2) PC4-51 http://flybase.org/reports/FBgn0015974 - gene - - - "l(2)PC4-G, l(2)PC4-51" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0003536 stp silver tips http://flybase.org/reports/FBgn0003536 - gene - - - stp - - 11-Aug-17 DroID_v2017_08 - - - - - - "visible,male sterile,viable,male,reduced" "macrochaeta,microchaeta" FBgn0033905 CG18324 - http://flybase.org/reports/FBgn0033905 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640628 CG18324 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG18324 11-Aug-17 DroID_v2017_08 "Drer\slc25a35, Drer\slc25a34" Scer\OAC1 - Xtro\slc25a34 "Mmus\Slc25a34, Mmus\Slc25a35" "Hsap\SLC25A35, Hsap\SLC25A34" "viable,fertile" FBgn0005184 l(2)S11 lethal of Seto 11 http://flybase.org/reports/FBgn0005184 - gene - - - l(2)S11 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "wing,leg" FBgn0028608 l(2)W17 lethal (2) W17 http://flybase.org/reports/FBgn0028608 gene - - - "l(2R)W17, l(2)W17" - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive" FBgn0031030 Tao Tao http://flybase.org/reports/FBgn0031030 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A8DYY6 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype" ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement response to cocaine ; GO:0042220 | inferred from mutant phenotype positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype hippo signaling ; GO:0035329 | inferred from genetic interaction with wts inferred from genetic interaction with yki inferred from genetic interaction with sav inferred from genetic interaction with hpo regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype inferred from genetic interaction with yki apoptotic process ; GO:0006915 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype central complex development ; GO:0048036 | inferred from mutant phenotype intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype negative regulation of organ growth ; GO:0046621 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from mutant phenotype response to nicotine ; GO:0035094 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern positive regulation of hippo signaling ; GO:0035332 | inferred from genetic interaction with wts inferred from genetic interaction with yki tissue homeostasis ; GO:0001894 | inferred from mutant phenotype microtubule ; GO:0005874 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 plasma membrane ; GO:0005886 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay "CG14217, dTao-1, AAF48973, TAO1, tao-1, Tao, Tao-1, tao, MARKK, tao1" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG14217 11-Aug-17 DroID_v2017_08 "Drer\taok2a, Drer\taok1b, Drer\taok2b, Drer\taok1a, Drer\taok3b, Drer\taok3a" Scer\KIC1 "Cele\B0198.3, Cele\kin-18, Cele\mes-1" "Xtro\taok2, Xtro\taok1, Xtro\taok3" "Mmus\Taok3, Mmus\Taok1, Mmus\Taok2" "Hsap\TAOK3, Hsap\TAOK1, Hsap\TAOK2" "lethal,recessive,viable,chemosensitive behavior defective,size defective,visible,lethal - all die before end of second instar larval stage,some die during second instar larval stage,increased cell number,somatic clone,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,fertile" "follicle cell,somatic clone,wing,eye,inter-ommatidial cell | pupal stage,head,adult cuticle,wing disc | third instar larval stage,eye disc,dorsal | third instar larval stage,posterior,ellipsoid body,mushroom body alpha-lobe,mushroom body beta-lobe,mushroom body gamma-lobe,adult mushroom body alpha'-lobe,adult mushroom body beta'-lobe,mushroom body vertical lobe" DRSC28431 IK 1.117810006 -2.14917207 -0.022359568 -1.362496271 0.45389412 1.648884309 FBgn0039632 Cul5 Cullin 5 http://flybase.org/reports/FBgn0039632 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000231993 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z6E0 ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Roc2 "germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from biological aspect of ancestor with PANTHER:PTN000232236 negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000231993 protein ubiquitination ; GO:0016567 | inferred by curator from GO:0031466,GO:0031625" Cul5-RING ubiquitin ligase complex ; GO:0031466 | inferred from direct assay Cul4-RING E3 ubiquitin ligase complex ; GO:0080008 | inferred from biological aspect of ancestor with PANTHER:PTN000748578 "CUL5, CG1401, Cul5, cul5, cul-5, Cullin5, Cullin 5, Cul-5" "IPR001373:Cullin, N-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016157:Cullin, conserved site, IPR016158:Cullin homology, IPR016159:Cullin repeat-like-containing domain, IPR019559:Cullin protein, neddylation domain" CG1401 11-Aug-17 DroID_v2017_08 "Drer\cul5a, Drer\cul5b" "Scer\CDC53, Scer\RTT101" Cele\cul-5 Xtro\cul5 Mmus\Cul5 Hsap\CUL5 "visible,lethal,increased cell number,lethal - all die before end of larval stage,some die during larval stage,conditional,viable,cell number defective,recessive,neuroanatomy defective" "macrochaeta,NMJ bouton,microchaeta,thecogen cell,ectopic,trichogen cell,eye,wing blade,heat sensitive,haltere,wing disc | third instar larval stage,arista,tarsal segment,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,supernumerary,sensory organ cell,adult thorax,antenna,wing,egg,pole cell,maternal effect,egg chamber,germarium,oocyte,polar follicle cell,nurse cell fusome,nurse cell" FBgn0051865 Ada1-1 transcriptional Adaptor 1-1 http://flybase.org/reports/FBgn0051865 protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity with SGD:S000006175 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001083423 histone acetylation ; GO:0016573 | inferred from sequence or structural similarity with SGD:S000006175 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with SGD:S000006175 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001083423 histone H3 acetylation ; GO:0043966 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay "BcDNA:RE30472, Ada1-1, CG31865, Ada1, ada1-1" IPR024738:Transcriptional coactivator Hfi1/Transcriptional adapter 1 CG31865 11-Aug-17 DroID_v2017_08 Drer\tada1 Scer\HFI1 - Xtro\tada1 Mmus\Tada1 Hsap\TADA1 FBgn0039328 CHKov2 CHKov2 http://flybase.org/reports/FBgn0039328 protein_coding_gene - - - "CG10675, CHKov2, ref(3)D" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG10675 11-Aug-17 DroID_v2017_08 Drer\LOC100150280 - "Cele\F59B1.8, Cele\F59B1.10" - - - viable FBgn0029858 mldr mulder http://flybase.org/reports/FBgn0029858 protein_coding_gene ribonuclease P activity ; GO:0004526 | inferred from biological aspect of ancestor with PANTHER:PTN001005190 mitochondrial tRNA processing ; GO:0090646 | inferred from mutant phenotype ATP metabolic process ; GO:0046034 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype tRNA 5'-leader removal ; GO:0001682 | inferred from biological aspect of ancestor with PANTHER:PTN001005190 mitochondrion ; GO:0005739 | inferred from direct assay "mldr, PRORP, CG15896" "IPR031595:Protein-only RNase P, C-terminal, IPR033495:Mitochondrial ribonuclease P protein 3" CG15896 11-Aug-17 DroID_v2017_08 Drer\si:dkeyp-33b5.4 - "Cele\ZC434.7, Cele\Y110A2AL.7" Xtro\kiaa0391 Mmus\1110008L16Rik Hsap\KIAA0391 FBgn0037633 CG9839 - http://flybase.org/reports/FBgn0037633 protein_coding_gene - - - CG9839 "IPR032718:PiggyBac transposable element-derived protein 4, C-terminal zinc-ribbon, IPR029526:PiggyBac transposable element-derived protein" CG9839 11-Aug-17 DroID_v2017_08 "Drer\dusp26, Drer\si:dkey-194g4.1, Drer\LOC100330143, Drer\pgbd5, Drer\pgbd4, Drer\zgc:162611" - - Xtro\LOC100487470 - "Hsap\PGBD3, Hsap\PGBD5, Hsap\PGBD2, Hsap\PGBD1, Hsap\ERCC6, Hsap\PGBD4" viable FBgn0026401 Nipped-B Nipped-B http://flybase.org/reports/FBgn0026401 "FBan0017704, FBgn0010505, FBgn0020393, FBgn0058281" protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Mau2 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype synaptonemal complex organization ; GO:0070193 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from genetic interaction with hh mitotic sister chromatid cohesion ; GO:0007064 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype transcriptional activation by promoter-enhancer looping ; GO:0071733 | inferred from genetic interaction with ct circadian sleep/wake cycle, sleep ; GO:0050802 | inferred from mutant phenotype maintenance of mitotic sister chromatid cohesion ; GO:0034088 | inferred from sequence or structural similarity with UniProtKB:Q6KC79 positive regulation of growth ; GO:0045927 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype learning ; GO:0007612 | inferred from mutant phenotype mitotic cohesin loading ; GO:0061780 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype synaptonemal complex assembly ; GO:0007130 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay SMC loading complex ; GO:0032116 | inferred from sequence or structural similarity with UniProtKB:Q6KC79 "CG17704, l(2)02047, CG40281, Nipped-B, NipB, nipped-B, NIPPED-B" "IPR024986:Sister chromatid cohesion C-terminal domain, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR026003:HEAT repeat associated with sister chromatid cohesion protein, IPR033031:SCC2/Nipped-B family" CG17704 11-Aug-17 DroID_v2017_08 "Drer\nipblb, Drer\nipbla" Scer\SCC2 Cele\pqn-85 Xtro\nipbl Mmus\Nipbl Hsap\NIPBL embryonic stage -- adult stage "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,mitotic cell cycle defective,viable,lethal - all die before end of larval stage,some die during larval stage,visible,dominant,lethal - all die before end of second instar larval stage,some die during second instar larval stage" "synaptonemal complex,wing blade,male genitalia,adult abdomen" DRSC07815 K -0.824601686 0.072978824 0.128906038 0.946324582 0.947222861 2.055067903 FBgn0033017 CG10465 - http://flybase.org/reports/FBgn0033017 protein_coding_gene - protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 - CG10465 "IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR011333:SKP1/BTB/POZ domain" CG10465 11-Aug-17 DroID_v2017_08 "Drer\tnfaip1, Drer\kctd13, Drer\kctd10" - "Cele\ZC239.13, Cele\T05E12.3, Cele\ZC239.2, Cele\F22E5.12, Cele\ZC239.5, Cele\D2045.8, Cele\F18A11.5, Cele\ZC239.4, Cele\F22E5.6, Cele\sdz-35, Cele\C40A11.3, Cele\B0281.4, Cele\ZC239.6, Cele\ZC239.15, Cele\C40A11.7, Cele\B0281.6, Cele\F22E5.13, Cele\fbxb-52, Cele\B0281.5, Cele\T08G3.13, Cele\C17F4.8, Cele\ZC239.3, Cele\F22E5.11, Cele\K02F6.8, Cele\C40A11.2, Cele\K02E7.4, Cele\ZC239.17, Cele\ZC239.14, Cele\F46G10.1, Cele\K02F6.5, Cele\C40A11.4, Cele\ZC239.16, Cele\C40A11.6, Cele\F22E5.8" "Xtro\kctd10, Xtro\tnfaip1" "Mmus\Kctd10, Mmus\Tnfaip1, Mmus\Kctd13" "Hsap\KCTD10, Hsap\KCTD13, Hsap\TNFAIP1" "viable,fertile" DRSC04848 K -0.584044141 0.510038795 -0.325417715 0.138431644 -1.97004794 -1.612206289 FBgn0027074 CG17324 - http://flybase.org/reports/FBgn0027074 FBgn0032712 protein_coding_gene UDP-glycosyltransferase activity ; GO:0008194 | inferred from sequence or structural similarity with UniProtKB:P18569 glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 xenobiotic metabolic process ; GO:0006805 | inferred from sequence or structural similarity with HGNC:12538 UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with UniProtKB:P18569 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:12538 "GH06505, BEST:GH06505, CG17324" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG17324 11-Aug-17 DroID_v2017_08 "Drer\ugt1b3, Drer\ugt5b2, Drer\ugt1b5, Drer\ugt5c2, Drer\ugt2a2, Drer\ugt5d1, Drer\ugt5c3, Drer\ugt2b6, Drer\ugt2a6, Drer\ugt5c1, Drer\ugt2a5, Drer\ugt1b2, Drer\ugt1b7, Drer\ugt1ab, Drer\ugt5g2, Drer\ugt5e1, Drer\ugt2b5, Drer\ugt5a1, Drer\ugt1b4, Drer\ugt5a5, Drer\ugt5a4, Drer\ugt5b6, Drer\ugt5b3, Drer\ugt5g1, Drer\ugt2b3, Drer\ugt2b1, Drer\ugt5f1, Drer\zgc:172315, Drer\ugt5b1, Drer\ugt8, Drer\ugt5a2" Scer\ATG26 "Cele\ugt-20, Cele\ugt-45, Cele\ugt-32, Cele\ugt-10, Cele\ugt-16, Cele\ugt-6, Cele\ugt-57, Cele\ugt-39, Cele\ugt-55, Cele\ugt-48, Cele\ugt-7, Cele\ugt-19, Cele\C03A7.12, Cele\ugt-53, Cele\ugt-59, Cele\ugt-34, Cele\ugt-17, Cele\ugt-37, Cele\ugt-14, Cele\ugt-58, Cele\ugt-31, Cele\ugt-15, Cele\ugt-35, Cele\C03A7.13, Cele\ugt-18, Cele\ugt-22, Cele\ugt-40, Cele\ugt-60, Cele\ugt-49, Cele\K04A8.10, Cele\F10D2.8, Cele\ugt-25, Cele\ugt-3, Cele\C23G10.6, Cele\ugt-54, Cele\ugt-26, Cele\ugt-27, Cele\ugt-46, Cele\ugt-62, Cele\ugt-44, Cele\ugt-21, Cele\ugt-2, Cele\ugt-24, Cele\ugt-8, Cele\ugt-43, Cele\ugt-12, Cele\ugt-30, Cele\ugt-50, Cele\ugt-28, Cele\ugt-38, Cele\ugt-33, Cele\ugt-42, Cele\H23N18.4, Cele\ugt-11, Cele\ugt-52, Cele\ugt-61, Cele\F54C1.1, Cele\Y43D4A.2, Cele\ugt-5, Cele\ugt-51, Cele\ugt-13, Cele\ugt-47, Cele\ugt-4, Cele\ugt-23, Cele\ugt-56, Cele\C55H1.1, Cele\ugt-9, Cele\ugt-36, Cele\ugt-29, Cele\ugt-1, Cele\ugt-41" "Xtro\ugt2a1, Xtro\ugt2b4, Xtro\ugt1a6, Xtro\ugt3a2, Xtro\ugt8" "Mmus\Ugt1a2, Mmus\Ugt2b1, Mmus\Ugt2b38, Mmus\Ugt2b37, Mmus\Ugt1a9, Mmus\Ugt2a3, Mmus\Ugt3a2, Mmus\Ugt1a6b, Mmus\Ugt1a7c, Mmus\Ugt2a1, Mmus\Ugt8a, Mmus\Ugt3a1, Mmus\Ugt1a1, Mmus\Ugt2b36, Mmus\Ugt2b34, Mmus\Ugt2b5, Mmus\Ugt2b35, Mmus\Ugt1a5" "Hsap\UGT3A2, Hsap\UGT2B15, Hsap\UGT2B7, Hsap\UGT1A8, Hsap\UGT2B28, Hsap\UGT2B4, Hsap\UGT1A4, Hsap\UGT1A10, Hsap\UGT8, Hsap\UGT3A1, Hsap\UGT1A3, Hsap\UGT1A9, Hsap\UGT1A5, Hsap\UGT1A6, Hsap\UGT2A2, Hsap\UGT1A1, Hsap\UGT2B17, Hsap\UGT2B10, Hsap\UGT2B11, Hsap\UGT2A3, Hsap\UGT1A7" "viable,fertile" FBgn0033555 RpS15Ab Ribosomal protein S15Ab http://flybase.org/reports/FBgn0033555 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000630 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000630 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000630 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CT22283, CG12324, RpS15Ab, RpS15A" IPR000630:Ribosomal protein S8 CG12324 11-Aug-17 DroID_v2017_08 Drer\rps15a "Scer\RPS22B, Scer\RPS22A" Cele\rps-22 Xtro\rps15a Mmus\Rps15a Hsap\RPS15A DRSC19831 EK -0.053939534 0.277854648 0.438674626 -1.605618004 1.293135208 5.622332563 FBgn0028399 TMS1 TMS1 http://flybase.org/reports/FBgn0028399 protein_coding_gene L-serine transmembrane transporter activity ; GO:0015194 | inferred from biological aspect of ancestor with PANTHER:PTN000043695 - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005016 "TMS1d, CG4672, TMS1" "IPR005016:Serine incorporator/TMS membrane protein, IPR029559:Membrane protein Tms1-like" CG4672 11-Aug-17 DroID_v2017_08 "Drer\serinc5, Drer\serinc2, Drer\serinc4, Drer\si:ch73-267c23.10, Drer\serinc2l, Drer\serinc1" Scer\TMS1 "Cele\R11H6.2, Cele\Y57E12AL.1" "Xtro\serinc5, Xtro\serinc2, Xtro\serinc1, Xtro\serinc3" "Mmus\Serinc3, Mmus\Serinc5, Mmus\Serinc1, Mmus\Serinc4, Mmus\Serinc2" "Hsap\SERINC4, Hsap\SERINC2, Hsap\SERINC5, Hsap\SERINC1, Hsap\SERINC3" "viable,fertile" FBgn0023388 Dap160 Dynamin associated protein 160 http://flybase.org/reports/FBgn0023388 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 protein binding ; GO:0005515 | inferred from physical interaction with par-6 inferred from physical interaction with aPKC synaptic vesicle endocytosis ; GO:0048488 | traceable author statement positive regulation of protein kinase activity ; GO:0045860 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype positive regulation of neuroblast proliferation ; GO:0002052 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay presynaptic membrane ; GO:0042734 | colocalizes_with inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay "dap160, CG1099, Dap160/intersectin, DAP160, DAP-160, p160, Dap160, noncoding_4110" "IPR000261:EH domain, IPR001452:SH3 domain, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR000504:RNA recognition motif domain" CG1099 11-Aug-17 DroID_v2017_08 "Drer\pacsin1b, Drer\trip10a, Drer\itsn1, Drer\itsn2a, Drer\pacsin1a, Drer\pacsin3, Drer\itsn2b, Drer\sh3d19" "Scer\PAN1, Scer\EDE1, Scer\SLA1, Scer\YSC84, Scer\END3, Scer\LSB1, Scer\IRS4, Scer\BZZ1, Scer\TAX4, Scer\LSB3" "Cele\itsn-1, Cele\B0303.7, Cele\sdpn-1, Cele\toca-1" "Xtro\itsn2, Xtro\itsn1, Xtro\fnbp1l" "Mmus\Pacsin2, Mmus\Fnbp1, Mmus\Sh3yl1, Mmus\Pacsin3, Mmus\Trip10, Mmus\Itsn2, Mmus\Pacsin1, Mmus\Dnmbp, Mmus\Sh3d19, Mmus\Itsn1, Mmus\Fnbp1l" "Hsap\ITSN1, Hsap\PACSIN1, Hsap\SH3D19, Hsap\FCHSD1, Hsap\ITSN2, Hsap\FNBP1, Hsap\FNBP1L, Hsap\PACSIN2, Hsap\TRIP10, Hsap\GRAP2, Hsap\SH3YL1, Hsap\PACSIN3" larval stage | third instar " bouton

, neuromuscular junction

" "neuroanatomy defective,lethal,viable,wild-type,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,uncoordinated,paralytic,heat sensitive,neurophysiology defective,endocytosis defective,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" "NMJ bouton,supernumerary,neuromuscular junction,bouton,synaptic vesicle,embryonic/larval neuromuscular junction,larval neuroblast & larval brain,embryonic/larval neuroblast,larval neuroblast & larval brainwor.PA,eo sensory structure,eo neuron,macrochaeta" FBgn0085408 Shroom Shroom http://flybase.org/reports/FBgn0085408 protein_coding_gene actin filament binding ; GO:0051015 | inferred from electronic annotation with InterPro:IPR027685 actin binding ; GO:0003779 | inferred from sequence or structural similarity with UniProtKB:A2ALU4 melanosome organization ; GO:0032438 | inferred from sequence or structural similarity with UniProtKB:A2ALU4 establishment or maintenance of actin cytoskeleton polarity ; GO:0030950 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from sequence or structural similarity with UniProtKB:A2ALU4 protein localization involved in establishment of planar polarity ; GO:0090251 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from direct assay protein localization to adherens junction ; GO:0071896 | inferred from mutant phenotype establishment of planar polarity of embryonic epithelium ; GO:0042249 | inferred from mutant phenotype cortical actin cytoskeleton ; GO:0030864 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:A2ALU4 cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity with UniProtKB:A2ALU4 bicellular tight junction ; GO:0005923 | inferred from sequence or structural similarity with UniProtKB:A2ALU4 "CG13942, CG8603, CG13944, Shroom, dmShroom, CG34379, dShrm, Shrm, Shrooom" "IPR014799:Apx/Shrm Domain 2, IPR030493:Protein Shroom, IPR027685:Shroom family" CG34379 11-Aug-17 DroID_v2017_08 "Drer\shroom2b, Drer\shroom4, Drer\shroom2a, Drer\shroom1, Drer\shroom3" Scer\SPC72 - "Xtro\shroom3, Xtro\shroom1, Xtro\shroom2" "Mmus\Shroom1, Mmus\Shroom4, Mmus\Shroom2, Mmus\Shroom3" "Hsap\SHROOM2, Hsap\SHROOM1, Hsap\SHROOM3, Hsap\SHROOM4" FBgn0042102 CG18745 - http://flybase.org/reports/FBgn0042102 protein_coding_gene - - - CG18745 "IPR014756:Immunoglobulin E-set, IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain" CG18745 11-Aug-17 DroID_v2017_08 "Drer\arrdc1a, Drer\zgc:110626, Drer\txnipa, Drer\arrdc2, Drer\LOC799768, Drer\si:ch211-130m23.2, Drer\arrdc3b, Drer\arrdc3a, Drer\txnipb, Drer\arrdc1b, Drer\zgc:110353" "Scer\RIM8, Scer\ALY1, Scer\ROD1, Scer\ROG3, Scer\ECM21, Scer\ALY2, Scer\CSR2, Scer\LDB19, Scer\ART5" "Cele\arrd-5, Cele\arrd-15, Cele\arrd-27, Cele\rnh-1.2, Cele\arrd-8, Cele\arrd-11, Cele\arrd-16, Cele\arrd-9, Cele\arrd-12, Cele\arrd-4, Cele\arrd-7, Cele\arrd-14, Cele\arrd-17, Cele\arrd-18, Cele\arrd-22, Cele\arrd-13, Cele\arrd-6, Cele\arrd-1, Cele\arrd-23, Cele\arrd-24, Cele\arrd-19, Cele\arrd-2, Cele\arrd-25, Cele\arrd-3" "Xtro\arrdc2, Xtro\arrdc3, Xtro\arrdc4, Xtro\txnip" "Mmus\Arrdc4, Mmus\Arrdc5, Mmus\Txnip, Mmus\Arrdc2, Mmus\Arrdc1, Mmus\Arrdc3" "Hsap\ARRDC1, Hsap\ARRDC4, Hsap\ARRDC2, Hsap\ARRDC3, Hsap\TXNIP, Hsap\ARRDC5" viable FBgn0028707 Mt2 Methyltransferase 2 http://flybase.org/reports/FBgn0028707 protein_coding_gene tRNA methyltransferase activity ; GO:0008175 | inferred from mutant phenotype DNA (cytosine-5-)-methyltransferase activity ; GO:0003886 | inferred from sequence or structural similarity methyltransferase activity ; GO:0008168 | inferred from sequence or structural similarity with MGI:MGI:1274787 DNA (cytosine-5-)-methyltransferase activity ; GO:0003886 | inferred from direct assay telomere maintenance ; GO:0000723 | inferred from mutant phenotype DNA methylation involved in embryo development ; GO:0043045 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype tRNA methylation ; GO:0030488 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype DNA hypermethylation ; GO:0044026 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from mutant phenotype DNA methylation ; GO:0006306 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype DNA methylation ; GO:0006306 | inferred from sequence or structural similarity with MGI:MGI:1274787 nuclear matrix ; GO:0016363 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleolus ; GO:0005730 | NOT inferred from direct assay nucleosome ; GO:0000786 | NOT inferred from direct assay cytoplasmic stress granule ; GO:0010494 | inferred from direct assay "dDnmt2, Mt2, DNMT, dDNMT, dnmt2, DmMT2, nmt2, Dnmt, CG10692, Dnmt2, dDNMT2, DNMT2" "IPR001525:C-5 cytosine methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR031303:DNA methylase, C-5 cytosine-specific, conserved site" CG10692 11-Aug-17 DroID_v2017_08 Drer\trdmt1 - - Xtro\trdmt1 Mmus\Trdmt1 Hsap\TRDMT1 " adult stage | female , embryonic stage && larval stage , embryonic stage " " organism

, ovary

" "immune response defective,viable,fertile,heat stress response defective,chemical sensitive,recessive,melanotic mass phenotype,conditional,non-suppressor of variegation,suppressor of variegation,dominant,short lived,stress response defective,long lived,chemical resistant" eye disc posterior to the morphogenetic furrow FBgn0030746 CG9981 - http://flybase.org/reports/FBgn0030746 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006539 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR006539 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from sequence or structural similarity with SGD:S000000024 phospholipid translocation ; GO:0045332 | inferred from sequence or structural similarity with SGD:S000000024 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR006539 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 integral component of membrane ; GO:0016021 | inferred from sequence model" "CG9981, DmCG9981" "IPR001757:P-type ATPase, IPR006539:P-type ATPase, subfamily IV, IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N, IPR032630:P-type ATPase, C-terminal, IPR032631:P-type ATPase, N-terminal" CG9981 11-Aug-17 DroID_v2017_08 "Drer\atp11a, Drer\atp8b1, Drer\atp11c, Drer\atp8b5a, Drer\atp8b4, Drer\atp8b3, Drer\si:dkey-211e20.10, Drer\atp10d, Drer\atp8b5b, Drer\atp8a2" "Scer\DNF1, Scer\DNF2, Scer\DRS2, Scer\DNF3" "Cele\tat-2, Cele\tat-1" "Xtro\atp11b, Xtro\atp11c, Xtro\atp8a1, Xtro\atp8b3, Xtro\atp11a" "Mmus\Atp11b, Mmus\Atp8a2, Mmus\Atp8a1, Mmus\Atp8b5, Mmus\Atp11a, Mmus\Atp8b2, Mmus\Atp11c, Mmus\Atp8b3, Mmus\Atp8b4, Mmus\Atp8b1" "Hsap\ATP8A1, Hsap\ATP8A2, Hsap\ATP11A, Hsap\ATP8B3, Hsap\ATP11C, Hsap\ATP8B4, Hsap\ATP8B1, Hsap\ATP11B, Hsap\ATP8B2" viable FBgn0037818 CG6465 - http://flybase.org/reports/FBgn0037818 protein_coding_gene aminoacylase activity ; GO:0004046 | inferred from electronic annotation with InterPro:IPR010159 metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR001261 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010159 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001261 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010159 CG6465 "IPR001261:ArgE/DapE/ACY1/CPG2/YscS, conserved site, IPR002933:Peptidase M20, IPR010159:N-acyl-L-amino-acid amidohydrolase, IPR011650:Peptidase M20, dimerisation domain" CG6465 11-Aug-17 DroID_v2017_08 "Drer\pm20d1.1, Drer\acy1, Drer\LOC100001620, Drer\pm20d1.2" Scer\CPS1 "Cele\C10C5.4, Cele\C06A6.4, Cele\C10C5.3, Cele\C10C5.5, Cele\C44E12.1" "Xtro\pm20d1, Xtro\acy1.1" "Mmus\Pm20d1, Mmus\Acy1" "Hsap\ACY1, Hsap\PM20D1, Hsap\ABHD14A-ACY1, Hsap\ABHD14A" "viable,fertile" FBgn0043362 bchs blue cheese http://flybase.org/reports/FBgn0043362 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 neuron development ; GO:0048666 | inferred from mutant phenotype positive regulation of organ growth ; GO:0046622 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from genetic interaction with Rab11 regulation of protein ubiquitination ; GO:0031396 | inferred from mutant phenotype regulation of synapse organization ; GO:0050807 | inferred from genetic interaction with Rab11 presynaptic active zone ; GO:0048786 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay "Bchs, CG9011, CG14001, DBEACH1, EP2299, bchd, BcDNA:SD12984, bchs, Beach1, alfy, Alfy" "IPR000306:FYVE zinc finger, IPR000409:BEACH domain, IPR001680:WD40 repeat, IPR011011:Zinc finger, FYVE/PHD-type, IPR023362:PH-BEACH domain, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011993:PH domain-like, IPR017455:Zinc finger, FYVE-related, IPR019775:WD40 repeat, conserved site, IPR011989:Armadillo-like helical, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR016024:Armadillo-type fold" CG14001 11-Aug-17 DroID_v2017_08 "Drer\wdfy4, Drer\wdr81, Drer\nsmaf, Drer\wdfy3, Drer\nbeab, Drer\lrba, Drer\nbeaa" Scer\BPH1 "Cele\wdfy-3, Cele\lyst-1" "Xtro\lyst, Xtro\wdfy3, Xtro\nsmaf" "Mmus\Wdr81, Mmus\Wdfy4, Mmus\Lrba, Mmus\Nsmaf, Mmus\Nbea, Mmus\Lyst, Mmus\Wdfy3" "Hsap\LYST, Hsap\LRBA, Hsap\NSMAF, Hsap\NBEA, Hsap\WDFY4, Hsap\WDFY3, Hsap\WDR81" "neuroanatomy defective,male fertile,female fertile,short lived,male,visible,wild-type,fertile,viable" "glial cell,eye disc,protocerebrum,ommatidium,retina,fan-shaped body,ellipsoid body,deuterocerebrum,lamina,medulla,subesophageal ganglion,rhabdomerecl7),brain,adult central nervous system,eye,growth coneGMR.PF,neuron & eye photoreceptor cellGMR.PF,growth cone & eye photoreceptor cellGMR.PF,dorsocentral bristle,scutellar bristle,adult abdomen & microchaeta-537.4,anterior fascicle & synapse,intersegmental nerve,embryonic/larval brain | third instar larval stage,embryonic/larval brain" FBgn0040069 vanin-like vanin-like http://flybase.org/reports/FBgn0040069 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ; GO:0016811 | inferred from electronic annotation with InterPro:IPR012101 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from biological aspect of ancestor with PANTHER:PTN000064607 hydrolase activity ; GO:0016787 | non-traceable author statement" nitrogen compound metabolic process ; GO:0006807 | inferred from electronic annotation with InterPro:IPR003010 extrinsic component of membrane ; GO:0019898 | non-traceable author statement "CG3648, CG32754, vanin-like, Vanin-like" "IPR003010:Carbon-nitrogen hydrolase, IPR012101:Biotinidase, eukaryotic" CG32754 11-Aug-17 DroID_v2017_08 "Drer\btd, Drer\nit2" "Scer\NTA1, Scer\NIT3" - "Xtro\nit2, Xtro\btd, Xtro\vnn1" "Mmus\Vnn1, Mmus\Vnn3, Mmus\Nit2, Mmus\Btd" "Hsap\VNN3, Hsap\BTD, Hsap\VNN2, Hsap\NIT2, Hsap\VNN1" "viable,partially lethal - majority die,some die during pupal stage" FBgn0033978 Cyp6a23 Cyp6a23 http://flybase.org/reports/FBgn0033978 protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "Cyp6a23, 6a23, CG10242, Cypa23, cyp6a23" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10242 11-Aug-17 DroID_v2017_08 "Drer\cyp4v7, Drer\cyp4t8, Drer\cyp26a1, Drer\cyp3c4, Drer\tbxas1, Drer\cyp3c2, Drer\cyp4f3, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp4v8, Drer\cyp3a65" "Scer\ERG5, Scer\ERG11" "Cele\cyp-43A1, Cele\cyp-13A3, Cele\cyp-13A2, Cele\cyp-31A2, Cele\cyp-13B1, Cele\cyp-32A1, Cele\cyp-25A1, Cele\cyp-13A10, Cele\cyp-29A4, Cele\cyp-37B1, Cele\cyp-32B1, Cele\cyp-29A3, Cele\cyp-25A3, Cele\cyp-42A1, Cele\cyp-13A4, Cele\cyp-44A1, Cele\cyp-25A4, Cele\cyp-31A3, Cele\cyp-13A7, Cele\cyp-25A2, Cele\cyp-13A1, Cele\cyp-13A6, Cele\cyp-13A5, Cele\cyp-29A2, Cele\cyp-13A12, Cele\cyp-13A11, Cele\cyp-13B2, Cele\cyp-25A6, Cele\cyp-13A8" "Xtro\LOC100494419, Xtro\cyp3a4, Xtro\cyp3a5, Xtro\tbxas1" "Mmus\Cyp3a44, Mmus\Cyp4a12b, Mmus\Cyp3a57, Mmus\Cyp3a13, Mmus\Cyp4a12a, Mmus\Cyp3a41b, Mmus\Cyp4a31, Mmus\Cyp3a16, Mmus\Cyp3a41a, Mmus\Cyp4f15, Mmus\Cyp4f13, Mmus\Cyp4f37, Mmus\Cyp4f16, Mmus\Cyp4a14, Mmus\Cyp4f14, Mmus\Cyp3a25, Mmus\Cyp3a11, Mmus\Tbxas1, Mmus\Cyp4f39, Mmus\Cyp26a1, Mmus\Cyp3a59, Mmus\Cyp4v3, Mmus\Cyp4f18, Mmus\Cyp4a10, Mmus\Cyp4a32, Mmus\Cyp4b1" "Hsap\CYP4F2, Hsap\CYP4F11, Hsap\CYP3A4, Hsap\CYP4X1, Hsap\CYP26A1, Hsap\CYP4F8, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A5, Hsap\CYP4F3, Hsap\CYP4A11, Hsap\TBXAS1, Hsap\CYP4B1, Hsap\CYP4V2, Hsap\CYP3A43, Hsap\CYP4F22, Hsap\CYP4A22, Hsap\CYP3A7, Hsap\CYP4F12, Hsap\CYP4Z1" viable FBgn0082582 tmod tropomodulin http://flybase.org/reports/FBgn0082582 protein_coding_gene tropomyosin binding ; GO:0005523 | inferred from electronic annotation with InterPro:IPR004934 tropomyosin binding ; GO:0005523 | non-traceable author statement actin binding ; GO:0003779 | inferred from sequence or structural similarity "pointed-end actin filament capping ; GO:0051694 | inferred from electronic annotation with InterPro:IPR004934, InterPro:IPR030137 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" cell cortex ; GO:0005938 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay "l(3)S130910, CG1539, spdo, Tmod, l(3)00848, E42, CG15540, CG11493, tmod, 1309/10, CT41421, CT3919" "IPR030137:Tropomodulin, invertebrate, IPR004934:Tropomodulin, IPR032675:Leucine-rich repeat domain, L domain-like" CG1539 11-Aug-17 DroID_v2017_08 "Drer\lmod2a, Drer\lmod3, Drer\tmod2, Drer\tmod4, Drer\tmod1, Drer\lmod1b, Drer\lmod2b, Drer\lmod1a" - "Cele\tmd-2, Cele\unc-94" "Xtro\lmod2, Xtro\tmod1, Xtro\tmod4, Xtro\tmod3, Xtro\lmod1, Xtro\lmod3, Xtro\tmod2" "Mmus\Tmod1, Mmus\Tmod2, Mmus\Lmod2, Mmus\Lmod1, Mmus\Lmod3, Mmus\Tmod4, Mmus\Tmod3" "Hsap\LMOD3, Hsap\LMOD1, Hsap\TMOD2, Hsap\TMOD4, Hsap\LMOD2, Hsap\TMOD1, Hsap\TMOD3" " larval stage--adult stage , embryonic stage | stage >=12 , embryonic stage -- adult stage , embryonic stage | stage 14-16 , embryonic stage | >=9-12 hr , larval stage--pupal stage , embryonic stage | stage >=9 , pupal stage , embryonic stage " " embryonic peripheral nervous system

, trichogen cell

, embryonic central nervous system | precursor

, tormogen cell

" " adult stage | male , adult stage , adult stage| female , pupal stage , embryonic stage -- adult stage , adult stage | day 1 , pupal stage && adult stage " " adult abdomen

, adult head

, muscle cell

, indirect flight muscle

, adult thorax

" "lethal,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,female fertile,germline clone,flight defective,heat sensitive" "striated muscle thin filamentMef2.PR,striated muscle thin filamentUH3,indirect flight muscle,indirect flight muscle & striated muscle thin filament,indirect flight muscle & striated muscle thick filament,indirect flight muscle & Z disc,myofibrilUH3,sarcomereUH3" DRSC15076 K -0.322387649 0.949061055 -0.168533051 0.939995242 2.081276554 0.690822899 FBgn0027498 CG2061 - http://flybase.org/reports/FBgn0027498 - protein_coding_gene - signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000296773 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000296773 "BcDNA:LD28247, CG2061" "IPR007822:Lanthionine synthetase C-like, IPR020464:LanC-like protein, eukaryotic" CG2061 11-Aug-17 DroID_v2017_08 "Drer\lancl1, Drer\lancl2" - - "Xtro\lancl1, Xtro\lancl3, Xtro\lancl2" "Mmus\Lancl1, Mmus\Lancl3, Mmus\Lancl2" "Hsap\LANCL1, Hsap\LANCL2, Hsap\LANCL3" viable FBgn0267433 kl-5 male fertility factor kl5 http://flybase.org/reports/FBgn0267433 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR011704 microtubule motor activity ; GO:0003777 | inferred from electronic annotation with InterPro:IPR004273, InterPro:IPR026983 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" "microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR004273, InterPro:IPR026983 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity" axonemal dynein complex ; GO:0005858 | inferred from mutant phenotype axonemal dynein complex ; GO:0005858 | inferred from sequence or structural similarity "CG40444, kl5, kl-5, CG45786, CG12573, Dhc-Yh3, CG17616, Dhc, DhcYh3, Lms4, Kl-5, CG41497, DHC4B" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026983:Dynein heavy chain, IPR003593:AAA+ ATPase domain, IPR011704:ATPase, dynein-related, AAA domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR004273:Dynein heavy chain domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2" CG45786 11-Aug-17 DroID_v2017_08 "Drer\dnah9l, Drer\dnah11" Scer\DYN1 - - "Mmus\Dnah9, Mmus\Dnah11" "Hsap\DNAH17, Hsap\DNAH9, Hsap\DNAH11" " adult stage | male , adult stage " " organism

, testis

" DRSC19615 I 1.516630924 -0.326109663 0.060611754 0.313036937 FBgn0034933 CG3735 - http://flybase.org/reports/FBgn0034933 protein_coding_gene U3 snoRNA binding ; GO:0034511 | inferred from biological aspect of ancestor with PANTHER:PTN000309515 rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000309515 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000309515 neurogenesis ; GO:0022008 | inferred from mutant phenotype" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000309515 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000309515 CG3735 "IPR010678:Digestive organ expansion factor, predicted" CG3735 11-Aug-17 DroID_v2017_08 Drer\diexf Scer\UTP25 Cele\Y41C4A.9 Xtro\diexf Mmus\Diexf Hsap\DIEXF "viable,fertile,lethal,recessive,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC04411 K 0.586279226 -0.21506252 -0.900198591 0.151494817 -1.726632855 -0.369966135 FBgn0260962 pic piccolo http://flybase.org/reports/FBgn0260962 protein_coding_gene damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000068363 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7K0T0 inferred from physical interaction with UniProtKB:Q9VMI1 wing disc development ; GO:0035220 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs eggshell chorion gene amplification ; GO:0007307 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | traceable author statement nucleotide-excision repair ; GO:0006289 | inferred from biological aspect of ancestor with PANTHER:PTN000068363 positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with UniProtKB:Q16531 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000068363 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q16531 cullin-RING ubiquitin ligase complex ; GO:0031461 | inferred from biological aspect of ancestor with PANTHER:PTN000068363 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000068362 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q16531 "DDB1, pic, Dbd1, l(3)S136603, 263/16, 1366/03, 1258/16, 0263/16, l(3)87Dh, CG7769, 153636_at, D-DDB1, d-ddb1, Ddb1, DDB-1, dDdb1, dDDB1, ddb1, PIC" "IPR004871:Cleavage/polyadenylation specificity factor, A subunit, C-terminal, IPR017986:WD40-repeat-containing domain, IPR031297:DNA damage-binding protein 1, IPR015943:WD40/YVTN repeat-like-containing domain" CG7769 11-Aug-17 DroID_v2017_08 "Drer\ddb1, Drer\LOC108179027" Scer\RSE1 Cele\ddb-1 Xtro\ddb1 Mmus\Ddb1 Hsap\DDB1 DRSC16639 I -1.117300938 -2.138487555 -1.09675522 -0.71885282 -0.422909447 -0.358336135 FBgn0037220 CG14641 - http://flybase.org/reports/FBgn0037220 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 U6 snRNA binding ; GO:0017070 | inferred from biological aspect of ancestor with PANTHER:PTN000363272 pre-mRNA binding ; GO:0036002 | inferred from biological aspect of ancestor with PANTHER:PTN000363272 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 spliceosomal snRNP assembly ; GO:0000387 | inferred from biological aspect of ancestor with PANTHER:PTN000363272" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2-type catalytic step 1 spliceosome ; GO:0071006 | inferred from biological aspect of ancestor with PANTHER:PTN000363272 Prp19 complex ; GO:0000974 | inferred from biological aspect of ancestor with PANTHER:PTN000363272 U2-type catalytic step 2 spliceosome ; GO:0071007 | inferred from biological aspect of ancestor with PANTHER:PTN000363272 "CG14641, cg14641" "IPR000504:RNA recognition motif domain, IPR000571:Zinc finger, CCCH-type" CG14641 11-Aug-17 DroID_v2017_08 Drer\rbm22 "Scer\CWC2, Scer\ECM2, Scer\NAM8" Cele\T11G6.8 Xtro\rbm22 "Mmus\Tex16, Mmus\Rbm22" Hsap\RBM22 "visible,partially lethal - majority die,some die during pupal stage" "heart primordium,chaeta,supernumerary,mesothoracic tergum" DRSC12227 I -0.175302174 1.971005021 1.007785317 1.15357981 -0.261834252 0.10818212 FBgn0086532 Spt-I Serine palmitoyltransferase subunit I http://flybase.org/reports/FBgn0086532 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR015421 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839 positive regulation of sphingolipid biosynthetic process ; GO:0090154 | inferred from mutant phenotype - "Spt-I, Spt1, l(2)SH2 1626, l(2)SH1626, lcb1, CG4016, SPT-I, dSpt1, l(2)49Fb, SPT1" "IPR004839:Aminotransferase, class I/classII, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG4016 11-Aug-17 DroID_v2017_08 Drer\sptlc1 Scer\LCB1 Cele\sptl-1 Xtro\sptlc1 Mmus\Sptlc1 Hsap\SPTLC1 DRSC06860 I 1.766104995 0.810334239 -0.243553813 0.30063024 -0.142366571 -0.309840471 FBgn0051894 CG31894 - http://flybase.org/reports/FBgn0051894 protein_coding_gene - - - CG31894 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC26190 K -0.57769996 0.277964178 0.089043711 -0.399753771 0.28057964 -1.767501283 FBgn0011666 msi musashi http://flybase.org/reports/FBgn0011666 - protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR034126 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | traceable author statement translation repressor activity, nucleic acid binding ; GO:0000900 | traceable author statement RNA binding ; GO:0003723 | inferred from sequence model translation regulator activity ; GO:0045182 | traceable author statement" negative regulation of translation ; GO:0017148 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype cell fate determination ; GO:0001709 | traceable author statement regulation of translation ; GO:0006417 | traceable author statement negative regulation of translation ; GO:0017148 | traceable author statement germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype stem cell population maintenance ; GO:0019827 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "SIDNA, DMSIDNA, clone 2.35, anon-EST:Liang-2.35, CG5099, msi, Msi, MSI, musashi, dMsi, dMSI" "IPR000504:RNA recognition motif domain, IPR034126:RNA-binding protein Musashi homologue, RNA recognition motif 2" CG5099 11-Aug-17 DroID_v2017_08 "Drer\hnrnpa0a, Drer\hnrpdl, Drer\dazap1, Drer\hnrnpa0l, Drer\msi2b, Drer\hnrnpa1b, Drer\hnrnpabb, Drer\hnrnpa0b, Drer\hnrnpa3, Drer\zgc:110796, Drer\msi1, Drer\msi2a, Drer\hnrnpa1a, Drer\hnrnpd, Drer\hnrnpaba" Scer\HRP1 "Cele\msi-1, Cele\H28G03.1" "Xtro\hnrnpa1, Xtro\hnrnpa2b1, Xtro\hnrnpdl, Xtro\dazap1, Xtro\hnrnpa0, Xtro\hnrnpd, Xtro\hnrnpa3, Xtro\hnrnpab, Xtro\msi1" "Mmus\Msi2, Mmus\Rbm31y, Mmus\Hnrnpa1, Mmus\Msi1, Mmus\Hnrnpa2b1, Mmus\Hnrnpd, Mmus\Dazap1, Mmus\Hnrnpdl, Mmus\Hnrnpab, Mmus\Hnrnpa0, Mmus\Hnrnpa3" "Hsap\HNRNPA1L2, Hsap\HNRNPA1, Hsap\MSI1, Hsap\HNRNPA3, Hsap\HNRNPDL, Hsap\HNRNPAB, Hsap\HNRNPD, Hsap\HNRNPA2B1, Hsap\MSI2, Hsap\DAZAP1, Hsap\HNRNPA0" "viable,fertile,wild-type,lethal,recessive,visible,meiotic cell cycle defective" "microchaeta & scutum,macrochaeta & scutum,testis,testis sheath muscle,socket,thecogen cell,neuron & microchaeta,neuron & macrochaeta,glial cell & macrochaeta,thecogen cell & medial triple row,thecogen cell & dorsal triple row,thecogen cell & twin sensillum of margin 1,thecogen cell & twin sensillum of margin 2,ommatidium,rhabdomere,trichogen cell,supernumerary,external sensory organ,germline stem cell,somatic clone,spermatogonium,tormogen cell" DRSC17003 K -1.347061584 -0.81107281 -0.916477796 -1.010736633 0.193288203 1.818307464 FBgn0037244 CG14647 - http://flybase.org/reports/FBgn0037244 protein_coding_gene - protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 - CG14647 "IPR000210:BTB/POZ domain, IPR001646:Pentapeptide repeat, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR011333:SKP1/BTB/POZ domain" CG14647 11-Aug-17 DroID_v2017_08 "Drer\kctd9b, Drer\kctd9a" - "Cele\ZC239.16, Cele\C40A11.3, Cele\C40A11.2, Cele\B0281.6, Cele\C40A11.6, Cele\F22E5.8, Cele\F22E5.12, Cele\ZC239.3, Cele\sdz-35, Cele\C17F4.8, Cele\K02F6.5, Cele\F22E5.6, Cele\ZC239.14, Cele\ZC239.15, Cele\C40A11.7, Cele\T05E12.3, Cele\C40A11.4, Cele\ZC239.4" Xtro\kctd9 Mmus\Kctd9 Hsap\KCTD9 "viable,lethal" FBgn0040056 CG17698 - http://flybase.org/reports/FBgn0040056 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with HGNC:1470 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from biological aspect of ancestor with PANTHER:PTN001218266 calmodulin binding ; GO:0005516 | inferred from biological aspect of ancestor with PANTHER:PTN001218266" peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:1470 protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 positive regulation of protein kinase activity ; GO:0045860 | inferred from biological aspect of ancestor with PANTHER:PTN001218266 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:1470 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001218266 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001218266 "CAMKIIB, CAMKIIb, CG40297, CG17698" "IPR011009:Protein kinase-like domain, IPR008271:Serine/threonine-protein kinase, active site, IPR000719:Protein kinase domain, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase, IPR017441:Protein kinase, ATP binding site" CG17698 11-Aug-17 DroID_v2017_08 "Drer\mylk2, Drer\LOC101884909, Drer\camkk1b, Drer\camkk1a" "Scer\YPK3, Scer\TOS3, Scer\SAK1, Scer\ELM1" Cele\ckk-1 "Xtro\pskh1, Xtro\camkk2" "Mmus\Camkk2, Mmus\Mylk, Mmus\Camkk1" "Hsap\CAMKK2, Hsap\CAMKK1, Hsap\MYLK2, Hsap\MYLK" viable FBgn0003134 Pp1alpha-96A Protein phosphatase 1alpha at 96A http://flybase.org/reports/FBgn0003134 - protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006186 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement" "beta-catenin destruction complex disassembly ; GO:1904886 | inferred from sequence or structural similarity with UniProtKB:P62139 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from genetic interaction with flw, Pp1-87B protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity protein dephosphorylation ; GO:0006470 | non-traceable author statement positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype" protein phosphatase type 1 complex ; GO:0000164 | inferred from sequence or structural similarity "CG6593, Pp1alpha-96A, PP1, Pp1-96A, DmPp1-96A, PP1alpha96A, PP1c, PP1 96A, PP1alpha[[1]], 96A, PP1c 96A, PP1 alpha96a, pp1alpha96A, PP1alpha" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like, IPR031675:Serine-threonine protein phosphatase, N-terminal" CG6593 11-Aug-17 DroID_v2017_08 "Drer\ppp1cc, Drer\ppp1caa, Drer\ppp1cab, Drer\ppp1cb" "Scer\PPQ1, Scer\PPZ1, Scer\GLC7, Scer\PPZ2" "Cele\gsp-2, Cele\gsp-1, Cele\ZK938.1, Cele\F52H3.6, Cele\F20D6.6, Cele\gsp-4, Cele\pph-1" "Xtro\ppp1cb, Xtro\ppp1ca, Xtro\ppp1cc" "Mmus\Ppp1ca, Mmus\Gm5601, Mmus\Ppp1cc, Mmus\Ppp1cb" "Hsap\PPP1CB, Hsap\PPP1CA, Hsap\PPP1CC" " adult stage , embryonic stage " "viable,fertile,lethal,immune response defective,conditional" enterocyte FBgn0037993 dpr15 defective proboscis extension response 15 http://flybase.org/reports/FBgn0037993 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 cellular_component ; GO:0005575 | no biological data available "CG10095, Dpr-15, CT28423, dpr15, Dpr15" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold" CG10095 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-65b12.12, Drer\kirrela, Drer\sdk1a, Drer\si:ch1073-459j12.1, Drer\LOC100333196, Drer\igsf9bb, Drer\ncam1b, Drer\ush2a, Drer\lrit1a, Drer\LOC101885444, Drer\kirrel3a, Drer\itgb4, Drer\kirrel3b, Drer\LOC101885725, Drer\dscama, Drer\kirrelb, Drer\lrit3a, Drer\lrit3b, Drer\sdk1b, Drer\paplna, Drer\si:ch211-163c2.2, Drer\igsf9a, Drer\lrit1b, Drer\kirrel3l" - Cele\zig-8 "Xtro\papln, Xtro\igsf9b, Xtro\kirrel2, Xtro\lrit3" "Mmus\Sdk1, Mmus\Cadm4, Mmus\Ptprq, Mmus\Lrit3, Mmus\Kirrel2, Mmus\Lrit1, Mmus\Papln, Mmus\Cadm2, Mmus\Kirrel3, Mmus\Cadm3, Mmus\Cadm1, Mmus\Igsf9b, Mmus\Kirrel" "Hsap\CADM2, Hsap\USH2A, Hsap\IGSF9B, Hsap\KIRREL2, Hsap\CADM3, Hsap\LRIT3, Hsap\LRIT1, Hsap\CADM1, Hsap\KIRREL, Hsap\SDK1, Hsap\KIRREL3, Hsap\CADM4, Hsap\PAPLN" "partially lethal - majority die,visible,body color defective,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC14187 IE -0.485308334 -1.528640449 1.326388548 -2.232291019 0.46110335 -0.273931199 FBgn0086134 Prosalpha2 Proteasome alpha2 subunit http://flybase.org/reports/FBgn0086134 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426 proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay" "Su(DTS), 153303_at, CG5266, dalpha2, PROS-Dm25g, PRC3, alpha2_dm, PROS Dm25, Su(DTS)-1, Pros25, Prosalpha2, PSA2_DROME, Alpha-2, alpha2, Prot. 25 Kda, alpha-2, pros25" "IPR001353:Proteasome, subunit alpha/beta, IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR023332:Proteasome alpha-type subunit, IPR034644:Proteasome subunit alpha2, IPR029055:Nucleophile aminohydrolases, N-terminal" CG5266 11-Aug-17 DroID_v2017_08 "Drer\si:rp71-45k5.4, Drer\psma2, Drer\psma8" Scer\PRE8 Cele\pas-2 "Xtro\psma5, Xtro\psma2, Xtro\psma7" "Mmus\Psma7, Mmus\Gm973, Mmus\Psma5, Mmus\Psma8, Mmus\Psma2" "Hsap\PSMA2, Hsap\PSMA5, Hsap\PSMA7, Hsap\PSMA8" DRSC16798 IEK 0.057792183 -2.905284425 -3.526330476 -1.686341625 1.627303321 1.963609334 FBgn0015663 Dot Dorothy http://flybase.org/reports/FBgn0015663 FBgn0031553 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG2788, Dot" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG2788 11-Aug-17 DroID_v2017_08 "Drer\ugt1ab, Drer\ugt1b3, Drer\ugt5b2, Drer\ugt2a6, Drer\ugt2b5, Drer\ugt5c3, Drer\ugt5e1, Drer\ugt5g2, Drer\ugt5b6, Drer\ugt2a2, Drer\ugt5b3, Drer\ugt5g1, Drer\ugt1b5, Drer\ugt5c2, Drer\ugt1b7, Drer\ugt2a5, Drer\ugt5a5, Drer\ugt1b4, Drer\ugt5a4, Drer\ugt1b2, Drer\ugt5f1, Drer\zgc:172315, Drer\ugt5a2, Drer\ugt5a1, Drer\ugt2b3, Drer\ugt8, Drer\ugt5b1, Drer\ugt2b6, Drer\ugt5c1, Drer\ugt5d1, Drer\ugt2b1" Scer\ATG26 "Cele\C55H1.1, Cele\ugt-11, Cele\F10D2.8, Cele\ugt-62, Cele\ugt-46, Cele\ugt-10, Cele\ugt-16, Cele\C23G10.6, Cele\F54C1.1, Cele\ugt-47, Cele\ugt-26, Cele\ugt-12, Cele\ugt-25, Cele\ugt-35, Cele\ugt-60, Cele\ugt-53, Cele\ugt-34, Cele\ugt-45, Cele\ugt-27, Cele\ugt-17, Cele\ugt-21, Cele\K04A8.10, Cele\ugt-19, Cele\ugt-37, Cele\ugt-33, Cele\ugt-43, Cele\ugt-40, Cele\ugt-52, Cele\ugt-48, Cele\ugt-61, Cele\ugt-1, Cele\ugt-56, Cele\ugt-30, Cele\ugt-54, Cele\ugt-2, Cele\ugt-5, Cele\ugt-7, Cele\C03A7.13, Cele\ugt-44, Cele\ugt-28, Cele\H23N18.4, Cele\ugt-8, Cele\ugt-15, Cele\ugt-36, Cele\ugt-55, Cele\ugt-49, Cele\ugt-9, Cele\ugt-38, Cele\ugt-3, Cele\ugt-13, Cele\ugt-41, Cele\Y43D4A.2, Cele\ugt-29, Cele\ugt-42, Cele\ugt-51, Cele\ugt-23, Cele\ugt-32, Cele\ugt-50, Cele\ugt-14, Cele\ugt-24, Cele\ugt-31, Cele\ugt-59, Cele\ugt-18, Cele\ugt-20, Cele\ugt-22, Cele\ugt-6, Cele\ugt-57, Cele\ugt-4, Cele\ugt-39, Cele\C03A7.12, Cele\ugt-58" "Xtro\ugt1a6, Xtro\ugt2b4, Xtro\ugt8, Xtro\ugt2a1, Xtro\ugt3a2" "Mmus\Ugt2b36, Mmus\Ugt3a1, Mmus\Ugt1a5, Mmus\Ugt2b34, Mmus\Ugt2b37, Mmus\Ugt1a6b, Mmus\Ugt1a7c, Mmus\Ugt2b35, Mmus\Ugt3a2, Mmus\Ugt2a1, Mmus\Ugt8a, Mmus\Ugt1a2, Mmus\Ugt1a1, Mmus\Ugt1a9, Mmus\Ugt2a3, Mmus\Ugt2b38, Mmus\Ugt2b1, Mmus\Ugt2b5" "Hsap\UGT2B15, Hsap\UGT8, Hsap\UGT2A2, Hsap\UGT1A3, Hsap\UGT1A10, Hsap\UGT2B7, Hsap\UGT2B28, Hsap\UGT1A1, Hsap\UGT2B4, Hsap\UGT1A7, Hsap\UGT1A4, Hsap\UGT3A1, Hsap\UGT3A2, Hsap\UGT2B10, Hsap\UGT2A3, Hsap\UGT2B11, Hsap\UGT1A8, Hsap\UGT2B17, Hsap\UGT1A6, Hsap\UGT1A9, Hsap\UGT1A5" "viable,visible,recessive" DRSC00748 K -0.543333073 0.458708028 -0.664736845 0.652753375 -1.571262226 0.024151163 FBgn0010416 TH1 TH1 http://flybase.org/reports/FBgn0010416 - protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of transcription elongation from RNA polymerase II promoter ; GO:0034244 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter during mitosis ; GO:0007070 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from physical interaction with UniProtKB:P92204 NELF complex ; GO:0032021 | inferred from physical interaction with Nelf-E inferred from physical interaction with NELF-B inferred from physical interaction with Nelf-A polytene chromosome puff ; GO:0005703 | inferred from direct assay transcriptional repressor complex ; GO:0017053 | inferred from direct assay "NELF, CG9984, NELF-D, TH1" "IPR006942:TH1 protein, IPR011989:Armadillo-like helical" CG9984 11-Aug-17 DroID_v2017_08 Drer\nelfcd - - Xtro\nelfcd Mmus\Nelfcd Hsap\NELFCD " embryonic stage , adult stage | female " "lethal,some die during second instar larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0030776 CG4653 - http://flybase.org/reports/FBgn0030776 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH179, CG4653" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG4653 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-165b19.8, Drer\si:ch211-165b19.9, Drer\zgc:163079, Drer\ovch1, Drer\si:dkey-21e2.3, Drer\gzmk, Drer\gzm3, Drer\zgc:165423, Drer\si:dkey-16l2.17, Drer\si:dkeyp-93a5.3, Drer\si:dkey-21e2.16, Drer\gzma, Drer\si:ch211-165b19.5, Drer\LOC558805, Drer\LOC100004427, Drer\zgc:92313, Drer\cfd" - "Cele\try-1, Cele\try-6" Xtro\gzmh "Mmus\Egfbp2, Mmus\Klk15, Mmus\Klk9" "Hsap\KLK9, Hsap\TPSD1, Hsap\KLK15" viable DRSC22857 I -0.382668935 -2.71834011 0.306100827 0.032357706 0.226747445 0.020581592 FBgn0259204 CG42308 - http://flybase.org/reports/FBgn0259204 protein_coding_gene - - - "CG42308, CG14428" IPR027858:Protein of unknown function DUF4516 CG42308 11-Aug-17 DroID_v2017_08 "Drer\lin37, Drer\smim4, Drer\si:ch211-68a17.7" - Cele\lin-37 Xtro\lin37 "Mmus\Smim4, Mmus\1190007I07Rik" "Hsap\C12orf73, Hsap\SMIM4, Hsap\LIN37" FBgn0033199 CG17985 - http://flybase.org/reports/FBgn0033199 protein_coding_gene - - - CG17985 IPR018392:LysM domain CG17985 11-Aug-17 DroID_v2017_08 "Drer\lysmd4, Drer\lysmd3" - Cele\lmd-1 "Xtro\lysmd4, Xtro\lysmd3" "Mmus\Lysmd4, Mmus\Lysmd3" "Hsap\LYSMD4, Hsap\LYSMD3" "partially lethal - majority die,some die during pupal stage" FBgn0026316 Ubc10 Ubiquitin conjugating enzyme 10 http://flybase.org/reports/FBgn0026316 FBgn0028742 protein_coding_gene ubiquitin conjugating enzyme activity ; GO:0061631 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with egg ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with ari-1 protein linear polyubiquitination ; GO:0097039 | inferred from direct assay protein ubiquitination ; GO:0016567 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "ubcD10, ubc, EG:52C10.4, CG5788, UbcD10, Ubc10" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG5788 11-Aug-17 DroID_v2017_08 "Drer\ube2l3a, Drer\ube2l3b" Scer\UBC4 "Cele\ubc-18, Cele\ubc-24" Xtro\ube2l3 "Mmus\Ube2l3, Mmus\Ube2l6, Mmus\Gm10705" "Hsap\UBE2L6, Hsap\UBE2L3" "neuroanatomy defective,somatic clone,viable,fertile,lethal,visible,body color defective,partially lethal - majority die,some die during pupal stage" "neuroblast,somatic clone,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC07568 E 0.07364313 -0.261077441 2.204031409 0.537881657 0.254657061 0.541279726 FBgn0053815 His3:CG33815 His3:CG33815 http://flybase.org/reports/FBgn0053815 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33815, His3:CG33815" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33815 11-Aug-17 DroID_v2017_08 "Drer\h3f3a, Drer\hist2h3c, Drer\hist2h3ca1, Drer\zgc:113983, Drer\si:ch211-113a14.27, Drer\h3f3c, Drer\zgc:113984, Drer\h3f3d, Drer\si:ch1073-429i10.3, Drer\cenpa, Drer\si:ch73-36p18.2, Drer\h3f3b.1, Drer\LOC108190746, Drer\LOC108190747, Drer\zgc:173552" "Scer\HHT1, Scer\HHT2, Scer\CSE4" "Cele\his-69, Cele\his-74, Cele\his-55, Cele\his-17, Cele\his-25, Cele\his-27, Cele\his-59, Cele\his-72, Cele\his-32, Cele\his-63, Cele\his-9, Cele\his-2, Cele\his-45, Cele\his-42, Cele\his-6, Cele\his-71, Cele\his-49, Cele\his-13" "Xtro\cenpa, Xtro\LOC100487179, Xtro\h3f3b, Xtro\hist2h3d" "Mmus\Hist1h3b, Mmus\Hist2h3c2, Mmus\Hist1h3e, Mmus\Hist1h3a, Mmus\Hist1h3h, Mmus\Hist1h3g, Mmus\Hist1h3i, Mmus\Hist2h3b, Mmus\Hist2h3c1, Mmus\H3f3b, Mmus\Cenpa, Mmus\Hist1h3d, Mmus\Hist1h3c, Mmus\H3f3a, Mmus\Hist1h3f" "Hsap\HIST1H3I, Hsap\HIST2H3C, Hsap\HIST1H3F, Hsap\H3F3C, Hsap\HIST1H3G, Hsap\HIST1H3H, Hsap\H3F3B, Hsap\HIST1H3D, Hsap\HIST1H3E, Hsap\HIST3H3, Hsap\HIST1H3J, Hsap\H3F3A, Hsap\HIST2H3D, Hsap\HIST1H3C, Hsap\HIST1H3B, Hsap\CENPA, Hsap\HIST2H3A, Hsap\HIST1H3A" FBgn0035085 CG3770 - http://flybase.org/reports/FBgn0035085 protein_coding_gene - establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement establishment of glial blood-brain barrier ; GO:0060857 | NOT inferred from mutant phenotype septate junction ; GO:0005918 | inferred from sequence or structural similarity with sinu "CT12588, CG3770" IPR019372:Lipoma HMGIC fusion partner-like protein CG3770 11-Aug-17 DroID_v2017_08 "Drer\lhfpl2a, Drer\lhfpl2b, Drer\lhfp, Drer\lhfpl3, Drer\lhfpl5a, Drer\lhfp, Drer\lhfpl4a" - - "Xtro\lhfpl2, Xtro\lhfpl1, Xtro\lhfpl3, Xtro\lhfpl4, Xtro\lhfpl5, Xtro\lhfp" "Mmus\Lhfpl1, Mmus\Lhfpl2, Mmus\Lhfp, Mmus\Tmem211, Mmus\Lhfpl5, Mmus\Lhfpl4" "Hsap\TMEM211, Hsap\LHFPL5, Hsap\LHFP, Hsap\LHFPL4, Hsap\LHFPL2, Hsap\LHFPL1" viable FBgn0051626 CG31626 - http://flybase.org/reports/FBgn0051626 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE20756, CG31626" IPR004019:YLP motif CG31626 11-Aug-17 DroID_v2017_08 Drer\pou2af1 - - - Mmus\Pou2af1 Hsap\POU2AF1 FBgn0038837 CG3822 - http://flybase.org/reports/FBgn0038837 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity with HGNC:4579 ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 regulation of synaptic activity ; GO:0060025 | inferred from sequence or structural similarity with GluRIIA plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with GluRIIA "CT12759, CG3822, DmelCG3822, DKaiRID" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG3822 11-Aug-17 DroID_v2017_08 "Drer\grik5, Drer\si:ch211-251b21.1, Drer\gria2b, Drer\grik4, Drer\LOC100334689, Drer\gria3b, Drer\si:dkey-183j2.10, Drer\gria1a, Drer\grik1a, Drer\gria3a, Drer\gria4b, Drer\grik2, Drer\LOC100331381, Drer\gria2a, Drer\grik1b" - "Cele\glr-5, Cele\glr-8, Cele\glr-2, Cele\glr-3, Cele\glr-1, Cele\glr-4, Cele\glr-6" "Xtro\gria4, Xtro\gria1, Xtro\gria3, Xtro\grik5, Xtro\grik2, Xtro\grik4, Xtro\grik1" "Mmus\Gria1, Mmus\Grik2, Mmus\Gria4, Mmus\Grik4, Mmus\Grik3, Mmus\Grik5, Mmus\Gria3, Mmus\Gria2, Mmus\Grik1" "Hsap\GRIK1, Hsap\GRIK4, Hsap\GRIA2, Hsap\GRIA4, Hsap\GRIK2, Hsap\GRIK3, Hsap\GRIA1, Hsap\GRIK5, Hsap\GRIA3" "viable,fertile" FBgn0015271 Orc5 Origin recognition complex subunit 5 http://flybase.org/reports/FBgn0015271 FBgn0001963 protein_coding_gene DNA replication origin binding ; GO:0003688 | inferred from biological aspect of ancestor with PANTHER:PTN000295037 mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from sequence or structural similarity with SGD:S000005205 lateral inhibition ; GO:0046331 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from direct assay nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay nuclear origin of replication recognition complex ; GO:0005664 | inferred from sequence or structural similarity with SGD:S000005205 nuclear origin of replication recognition complex ; GO:0005664 | inferred from sequence or structural similarity "ORC5, ORC, l(2)34Df, orc5, BG:DS00941.8, DmORC5, l(2)br39, br39, CG7833, Orc5, dORC5, D-orc5, DmOrc5" "IPR003593:AAA+ ATPase domain, IPR020796:Origin recognition complex, subunit 5, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7833 11-Aug-17 DroID_v2017_08 Drer\orc5 Scer\ORC5 Cele\orc-5 Xtro\orc5 Mmus\Orc5 Hsap\ORC5 embryonic stage && larval stage "wild-type,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,visible" "mitotic cell cycle,mitosis & nuclear chromosome,chromosome, centromeric region,imaginal disc,spindle,mitotic metaphase,follicle cell,mitotic metaphaseb84a9),mitosis & nuclear chromosomeb84a9),chaeta,trichogen cell" FBgn0053870 His2B:CG33870 His2B:CG33870 http://flybase.org/reports/FBgn0053870 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33870, His2B:CG33870" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33870 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.11, Drer\zgc:194989, Drer\LOC100334559, Drer\si:ch1073-159d7.5, Drer\si:ch211-113a14.29, Drer\si:ch211-113a14.28, Drer\si:dkey-261m9.6, Drer\si:dkey-23a13.16, Drer\si:ch1073-159d7.13, Drer\si:ch73-36p18.3, Drer\si:ch73-368j24.8, Drer\zgc:114046, Drer\hist1h2ba, Drer\zgc:173585, Drer\si:dkey-23a13.1, Drer\LOC100329290, Drer\si:dkey-261m9.19, Drer\zgc:92591, Drer\si:ch1073-153i20.3, Drer\ano9a, Drer\si:dkey-108k21.27, Drer\LOC100334869, Drer\hist2h2l, Drer\zgc:173587, Drer\si:dkey-23a13.5, Drer\si:ch211-113a14.11, Drer\LOC100329560" "Scer\HTB1, Scer\HTB2" "Cele\his-34, Cele\his-8, Cele\his-54, Cele\his-11, Cele\his-48, Cele\his-44, Cele\his-4, Cele\his-52, Cele\his-41, Cele\his-66, Cele\his-15, Cele\his-22, Cele\his-29, Cele\his-58, Cele\his-62, Cele\his-39, Cele\his-20" "Xtro\LOC101733171, Xtro\LOC100497082, Xtro\LOC100496181, Xtro\LOC101731067, Xtro\LOC100495041, Xtro\LOC101734494, Xtro\hist1h2bm, Xtro\LOC100498072, Xtro\LOC100496445, Xtro\LOC100495415, Xtro\LOC100495396, Xtro\hist1h2bk, Xtro\LOC100486150, Xtro\LOC100498329, Xtro\LOC101735164, Xtro\LOC100496436, Xtro\LOC101735218, Xtro\LOC100486870, Xtro\LOC100498647, Xtro\LOC101731959, Xtro\LOC101733489, Xtro\LOC100492632, Xtro\LOC100495578, Xtro\hist1h2bj, Xtro\LOC101731852, Xtro\LOC100485294, Xtro\LOC101734862, Xtro\LOC100485134, Xtro\LOC101733828, Xtro\LOC100498553, Xtro\LOC100487485, Xtro\hist2h2be, Xtro\LOC101730940, Xtro\LOC100497915" "Mmus\Hist1h2bn, Mmus\Hist1h2bb, Mmus\Hist3h2ba, Mmus\Hist1h2bm, Mmus\Hist1h2be, Mmus\Hist1h2bl, Mmus\Hist1h2bp, Mmus\Hist1h2bj, Mmus\Hist1h2br, Mmus\H2bfm, Mmus\Hist1h2bf, Mmus\1700024P04Rik, Mmus\Hist1h2bg, Mmus\Hist1h2bq, Mmus\Hist1h2bk, Mmus\Hist2h2bb, Mmus\Hist1h2bh, Mmus\Hist1h2bc, Mmus\Hist1h2ba, Mmus\Hist2h2be" "Hsap\HIST1H2BJ, Hsap\HIST1H2BH, Hsap\HIST1H2BB, Hsap\HIST1H2BM, Hsap\HIST1H2BL, Hsap\HIST1H2BG, Hsap\H2BFWT, Hsap\H2BFM, Hsap\HIST1H2BK, Hsap\HIST1H2BN, Hsap\HIST1H2BA, Hsap\HIST1H2BF, Hsap\HIST2H2BF, Hsap\HIST1H2BO, Hsap\HIST3H2BB, Hsap\HIST2H2BE, Hsap\HIST1H2BI, Hsap\HIST1H2BD, Hsap\HIST1H2BE, Hsap\HIST1H2BC" FBgn0053513 Nmdar2 NMDA receptor 2 http://flybase.org/reports/FBgn0053513 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 NMDA glutamate receptor activity ; GO:0004972 | contributes_to inferred from direct assay NMDA glutamate receptor activity ; GO:0004972 | inferred from sequence or structural similarity ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 ionotropic glutamate receptor signaling pathway ; GO:0035235 | inferred from direct assay long-term memory ; GO:0007616 | inferred from genetic interaction with Nmdar1 medium-term memory ; GO:0072375 | inferred from mutant phenotype sensory perception of touch ; GO:0050975 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype ionotropic glutamate receptor complex ; GO:0008328 | inferred from physical interaction with Nmdar1 integral component of membrane ; GO:0016021 | inferred from direct assay "Nmdar2, dNR2, EG:80H7.7, DrNR2, CG14793, dnmdar-II, CT34603, 79G8T, anon-sts34, ESTS:79G8T, CG14794, CG33513, NMDAR2, NR2, DmelNmdar2, dsNR2, NMDAR, nr2" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG33513 11-Aug-17 DroID_v2017_08 "Drer\grin1b, Drer\grin2aa, Drer\LOC100329743, Drer\grin2da, Drer\grin1a, Drer\grin3bb, Drer\grin2cb, Drer\grin2ab, Drer\grin3a, Drer\grin3ba, Drer\grin2bb, Drer\LOC100149482" - "Cele\glr-2, Cele\glr-1, Cele\nmr-2" "Xtro\grin2d, Xtro\grin2b, Xtro\grin1, Xtro\grin2c, Xtro\grin3b" "Mmus\Grin3b, Mmus\Grin3a, Mmus\Grin2c, Mmus\Grin2a, Mmus\Grin1, Mmus\Grin2b, Mmus\Grin2d" "Hsap\GRIN1, Hsap\GRIN3B, Hsap\GRIN2D, Hsap\GRIN3A, Hsap\GRIN2A, Hsap\GRIN2C, Hsap\GRIN2B" "memory defective,viable,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,touch sensitivity defective" "dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0029941 CG1677 - http://flybase.org/reports/FBgn0029941 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay CG1677 "IPR000571:Zinc finger, CCCH-type" CG1677 11-Aug-17 DroID_v2017_08 Drer\zc3h18 Scer\ZDS1 - Xtro\mkrn2 Mmus\Zc3h18 Hsap\ZC3H18 "viable,fertile,female fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,female semi-fertile" embryonic/larval neuroblast DRSC18116 I 2.126773905 -0.438586079 0.170115823 -0.091099239 0.461232215 -0.144824667 FBgn0028482 bdl borderless http://flybase.org/reports/FBgn0028482 protein_coding_gene protein binding involved in cell-cell adhesion ; GO:0098632 | inferred from physical interaction with tutl R7 cell development ; GO:0045467 | inferred from mutant phenotype inferred from genetic interaction with tutl neuron cell-cell adhesion ; GO:0007158 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay "GH11322, BcDNA:GH11322, CT35491, bdl, CG16857, borderless" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG16857 11-Aug-17 DroID_v2017_08 "Drer\igsf9ba, Drer\LOC565947, Drer\igsf9bb, Drer\zgc:154125, Drer\si:ch211-57n23.4, Drer\igsf9a, Drer\igsf9b, Drer\igdcc3" - "Cele\dim-1, Cele\igcm-2" "Xtro\LOC100496351, Xtro\hepacam2, Xtro\igsf9b, Xtro\igsf9, Xtro\fcrl3, Xtro\igsf11, Xtro\fcgr1, Xtro\LOC100486104, Xtro\LOC100489139" "Mmus\Igdcc3, Mmus\Fcgr3, Mmus\Igsf9b, Mmus\Fcrl5, Mmus\Igsf9, Mmus\Fcgr1, Mmus\Fcgr4, Mmus\Fcer1a, Mmus\Fcrla, Mmus\Fcgr2b, Mmus\Fcrlb" "Hsap\IGDCC3, Hsap\FCRLA, Hsap\FCRL5, Hsap\FCGR3A, Hsap\FCGR3B, Hsap\IGSF9, Hsap\FCGR2A, Hsap\HEPACAM, Hsap\CD276, Hsap\CD86, Hsap\FCRLB, Hsap\FCRL4, Hsap\FCGR2B, Hsap\FCGR1A, Hsap\FCGR1B, Hsap\IL1R1, Hsap\FCER1A, Hsap\FCRL3, Hsap\IGSF9B" viable DRSC00271 K -0.757243513 0.24895887 0.052018036 -0.041024236 -0.132413173 2.121578158 FBgn0031888 Pvf2 PDGF- and VEGF-related factor 2 http://flybase.org/reports/FBgn0031888 protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR000072 vascular endothelial growth factor receptor binding ; GO:0005172 | inferred from sequence or structural similarity with HGNC:12680 "hemocyte migration ; GO:0035099 | traceable author statement hemocyte migration ; GO:0035099 | inferred from genetic interaction with Pvf3 vascular endothelial growth factor receptor signaling pathway ; GO:0048010 | inferred from sequence or structural similarity with HGNC:12680 hemocyte proliferation ; GO:0035172 | traceable author statement hemocyte migration ; GO:0035099 | inferred from expression pattern inferred from genetic interaction with Pvf1, Pvf3 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000072 "PVF, VEGF-2, PVF2, VEGF, PVFs, pvf2, VEGF27Cb, Vegf27Cb, CG13780, DmVEGF-2, Pvf2, PV2, Pvf" "IPR029034:Cystine-knot cytokine, IPR000072:PDGF/VEGF domain" CG13780 11-Aug-17 DroID_v2017_08 - - - - Mmus\Vegfc Hsap\VEGFC " embryonic stage | stage 9-15 , embryonic stage | stage 9-11 , embryonic stage | stage 11-13 " " embryonic foregut

, embryonic hindgut

, Malpighian tubule

, posterior ectoderm

restricted , ventral nerve cord

" "viable,lethal,partially,some die during pupal stage,lethal - all die before end of pupal stage" "embryonic hemocyte,adult midgut,ventral nerve cord | embryonic stage,hemocyte,intestinal stem cell,enteroendocrine cell,supernumerary,enterocyte,embryonic/larval hemocyte,crystal cell,plasmatocyte" DRSC02283 K -0.279636555 0.173661761 -0.264803984 0.486477651 1.79118557 1.900943728 FBgn0034392 MFS15 Major Facilitator Superfamily Transporter 15 http://flybase.org/reports/FBgn0034392 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 "MFS15, CG15094" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG15094 11-Aug-17 DroID_v2017_08 "Drer\slc17a6a, Drer\slc17a5, Drer\slc17a6b, Drer\si:ch1073-513e17.1, Drer\slc17a8, Drer\ppt1, Drer\slc17a7a" "Scer\TNA1, Scer\DAL5, Scer\YIL166C, Scer\THI73, Scer\FEN2" "Cele\F59A1.13, Cele\K08C7.1, Cele\vglu-3, Cele\T19D12.9, Cele\T27D12.1, Cele\C39E9.7, Cele\F56A4.10, Cele\slc-17.4, Cele\Y4C6B.4, Cele\F10C2.7, Cele\T02B11.6, Cele\slc-17.9, Cele\slc-17.1, Cele\slc-17.2, Cele\R10D12.1, Cele\K11G9.5, Cele\T28H11.8, Cele\Y19D10A.8, Cele\Y4C6B.3, Cele\D1046.4, Cele\Y51B9A.6, Cele\T01H3.3, Cele\F44E7.7, Cele\F41C3.2, Cele\Y15E3A.4, Cele\M117.1, Cele\C18H9.5, Cele\T22F3.8, Cele\eat-4, Cele\Y19D10A.4, Cele\T22F3.11, Cele\slc-17.8, Cele\H11E01.2, Cele\M162.5, Cele\T11G6.4, Cele\C01B4.7, Cele\T22F3.10, Cele\F56A4.12, Cele\C35A5.3, Cele\F11A5.9, Cele\Y19D10A.11, Cele\W04C9.6, Cele\Y19D10A.5, Cele\C01B4.8, Cele\slc-17.5, Cele\slc-17.3, Cele\T19D12.10, Cele\vglu-2, Cele\T22F3.7, Cele\C18D1.2, Cele\cima-1" Xtro\slc17a5 "Mmus\Slc17a8, Mmus\Slc17a3, Mmus\Slc17a4, Mmus\Slc17a7, Mmus\Slc37a2, Mmus\Slc17a2, Mmus\Slc17a6, Mmus\Slc17a1, Mmus\Slc17a5" "Hsap\SLC17A3, Hsap\SLC17A2, Hsap\SLC17A7, Hsap\SLC17A8, Hsap\SLC17A4, Hsap\SLC17A5, Hsap\SLC17A6, Hsap\SLC17A1, Hsap\SLC37A2" "viable,fertile" DRSC06523 I 2.207208185 0.138417628 -0.349999498 0.070766584 0.418157363 0.270200772 FBgn0038934 Gld2 GLD2 poly(A) polymerase http://flybase.org/reports/FBgn0038934 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P48598 inferred from physical interaction with UniProtKB:Q9NFU0 polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from sequence or structural similarity with WB:WBGene00001596 polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from direct assay polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from sequence or structural similarity with UniProtKB:Q6PIY7 long-term memory ; GO:0007616 | inferred from mutant phenotype RNA polyadenylation ; GO:0043631 | inferred from sequence or structural similarity with UniProtKB:Q6PIY7 cytoplasm ; GO:0005737 | inferred from direct assay neuron projection ; GO:0043005 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "DmCG5732, CG5732, Gld2, DmGLD2, Dm1" IPR002058:PAP/25A-associated CG5732 11-Aug-17 DroID_v2017_08 "Drer\zcchc11, Drer\zcchc6, Drer\mtpap, Drer\tut1, Drer\papd4" - "Cele\F31C3.2, Cele\cid-1, Cele\mut-2, Cele\Y34F4.3, Cele\F43E2.1, Cele\F43H9.3, Cele\usip-1, Cele\C53A5.16, Cele\R07H5.11, Cele\gld-2, Cele\pup-3, Cele\T08B2.4, Cele\pup-2" "Xtro\zcchc11, Xtro\papd4, Xtro\tut1, Xtro\mtpap, Xtro\zcchc6" "Mmus\Zcchc11, Mmus\Mtpap, Mmus\Papd4, Mmus\Zcchc6, Mmus\Tut1" "Hsap\TUT1, Hsap\MTPAP, Hsap\ZCCHC11, Hsap\ZCCHC6, Hsap\PAPD4" "memory defective,heat sensitive" DRSC23037 K -1.500219939 -0.219348702 FBgn0031548 CG8852 - http://flybase.org/reports/FBgn0031548 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT9284, CG8852" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG8852 11-Aug-17 DroID_v2017_08 "Drer\LOC101882074, Drer\lrit1a, Drer\lrit3a, Drer\lrit3b, Drer\LOC100330212, Drer\lrit1b, Drer\lrrc53, Drer\si:dkey-52j6.3" - "Cele\tol-1, Cele\pan-1, Cele\lron-9" - "Mmus\Lgr6, Mmus\Lrit1, Mmus\Cpn2, Mmus\Lrrc52, Mmus\Tril, Mmus\Lrg1, Mmus\Lrrc26, Mmus\Lrit3, Mmus\Lgr5, Mmus\Chadl" "Hsap\LGR6, Hsap\LRG1, Hsap\LRRC26, Hsap\LRRC52, Hsap\LGR5, Hsap\CPN2, Hsap\TRIL, Hsap\LRIT1, Hsap\CHADL, Hsap\LRIT3" viable DRSC00719 K -0.26838558 0.093346444 -0.171114927 1.091080398 -0.39715126 -2.382565628 FBgn0031633 Fnta Farnesyl transferase alpha http://flybase.org/reports/FBgn0031633 protein_coding_gene protein prenyltransferase activity ; GO:0008318 | inferred from electronic annotation with InterPro:IPR002088 protein prenylation ; GO:0018342 | inferred from electronic annotation with InterPro:IPR002088 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D - "CG2976, FNTA, Fnta" "IPR002088:Protein prenyltransferase, alpha subunit" CG2976 11-Aug-17 DroID_v2017_08 Drer\fnta Scer\RAM2 Cele\fnta-1 Xtro\fnta Mmus\Fnta Hsap\FNTA "planar polarity defective,viable,visible" "wing | pupal stage,wing hair | pupal stage,mesothoracic tergum" DRSC00557 K -0.713231025 0.564055174 -0.305507899 0.006719208 -0.341854177 -4.007806652 FBgn0037665 St2 Sulfotransferase 2 http://flybase.org/reports/FBgn0037665 protein_coding_gene sulfotransferase activity ; GO:0008146 | inferred from sequence or structural similarity with St1 sulfation ; GO:0051923 | inferred from sequence or structural similarity with St1 cytosol ; GO:0005829 | non-traceable author statement "CG16733, dmST2, St2, st2" "IPR000863:Sulfotransferase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG16733 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-236e20.3, Drer\sult3st2, Drer\sult2st3, Drer\sult3st1, Drer\sult1st2, Drer\sult1st6, Drer\sult1st3, Drer\sult5a1, Drer\sult1st5, Drer\sult2st1, Drer\sult4a1, Drer\sult1st8, Drer\sult1st7, Drer\sult1st4, Drer\sult2st2, Drer\sult3st3, Drer\sult3st4, Drer\sult1st1, Drer\sult6b1" - Cele\ssu-1 "Xtro\sult1a1, Xtro\sult2b1, Xtro\sult1e1, Xtro\LOC496998, Xtro\LOC100497264, Xtro\sult1c2, Xtro\sult1b1, Xtro\sult4a1, Xtro\sult6b1" "Mmus\Sult2a7, Mmus\Sult1d1, Mmus\Sult1e1, Mmus\Sult1c2, Mmus\Sult2a4, Mmus\Sult2a6, Mmus\Sult1b1, Mmus\Sult2b1, Mmus\Sult3a1, Mmus\Sult3a2, Mmus\Sult1a1, Mmus\Sult4a1, Mmus\Sult2a3, Mmus\Sult2a5, Mmus\Sult1c1, Mmus\Sult6b2, Mmus\Sult2a1, Mmus\Sult5a1, Mmus\Sult6b1, Mmus\Sult2a2, Mmus\Sult2a8" "Hsap\SULT1A2, Hsap\SULT1B1, Hsap\SULT1E1, Hsap\SULT2B1, Hsap\SULT4A1, Hsap\SULT1C4, Hsap\SULT6B1, Hsap\SULT1C3, Hsap\SULT1C2, Hsap\SULT2A1, Hsap\SULT1A3, Hsap\SULT1A1, Hsap\SULT1A4" viable DRSC15142 I -1.652370583 1.144830947 0.952527013 0.628066 0.720347699 0.023607367 FBgn0262717 Skeletor Skeletor http://flybase.org/reports/FBgn0262717 protein_coding_gene structural molecule activity ; GO:0005198 | inferred from direct assay dopamine beta-monooxygenase activity ; GO:0004500 | traceable author statement spindle assembly ; GO:0051225 | inferred from direct assay catecholamine metabolic process ; GO:0006584 | traceable author statement nucleus organization ; GO:0006997 | non-traceable author statement polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG43161, Skeletor, 2Ab3, CG33676, CG14682, skeletor, CG14681, CG31261, CG32922" "IPR019545:DM13 domain, IPR005018:DOMON domain" CG43161 11-Aug-17 DroID_v2017_08 - - "Cele\W01C8.5, Cele\H06A10.1" - Mmus\Thbd Hsap\THBD "viable,fertile" DRSC14906 E 0.382358452 0.293228588 2.163849219 0.83989019 0.709770824 0.158319716 FBgn0039777 Jon99Fii Jonah 99Fii http://flybase.org/reports/FBgn0039777 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 endopeptidase activity ; GO:0004175 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG2229, Jon99F, SP135, Jon99Fii" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG2229 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-78l4.10, Drer\zgc:163025, Drer\prss59.2" - Cele\svh-1 - "Mmus\C1s1, Mmus\C1s2, Mmus\Cela2a, Mmus\Ctrc, Mmus\Ctrl, Mmus\Ctrb1, Mmus\Cela1, Mmus\Cela3b, Mmus\F9, Mmus\Cela3a" Hsap\PROC viable FBgn0033391 CG8026 - http://flybase.org/reports/FBgn0033391 protein_coding_gene folic acid transporter activity ; GO:0008517 | inferred from sequence or structural similarity with UniProtKB:Q9H2D1 FAD transmembrane transporter activity ; GO:0015230 | inferred from biological aspect of ancestor with PANTHER:PTN000641020 folic acid transporter activity ; GO:0008517 | inferred from biological aspect of ancestor with PANTHER:PTN000641020 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 mitochondrial transport ; GO:0006839 | inferred from sequence or structural similarity with UniProtKB:Q9H2D1 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 folic acid transport ; GO:0015884 | inferred from sequence or structural similarity with UniProtKB:Q9H2D1 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q9H2D1 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "anon-WO0242455.7, anon-WO0242455.6, anon-WO0242455.53, CG8026, Dromel_CG8026_FBtr0088611_mORF" "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG8026 11-Aug-17 DroID_v2017_08 "Drer\slc25a32a, Drer\slc25a32b" "Scer\FLX1, Scer\YEA6, Scer\YIA6" Cele\slc-25A32 Xtro\slc25a32 Mmus\Slc25a32 Hsap\SLC25A32 viable FBgn0033122 CG17002 - http://flybase.org/reports/FBgn0033122 protein_coding_gene - - - CG17002 IPR026094:G protein pathway suppressor 2 CG17002 11-Aug-17 DroID_v2017_08 Drer\gps2 - - Xtro\gps2 Mmus\Gps2 Hsap\GPS2 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0043791 phu phurba tashi http://flybase.org/reports/FBgn0043791 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 response to hypoxia ; GO:0001666 | inferred from mutant phenotype dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 response to nicotine ; GO:0035094 | inferred from expression pattern cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 "CG8147, 154821_at, BEST:LD38109, phu" "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG8147 11-Aug-17 DroID_v2017_08 "Drer\alpi.2, Drer\alp3, Drer\alpl, Drer\alpi.1" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1" "Mmus\Alppl2, Mmus\Alpl, Mmus\Alpi, Mmus\Akp3" "Hsap\ALPP, Hsap\ALPPL2, Hsap\ALPL, Hsap\ALPI" viable FBgn0264693 ens ensconsin http://flybase.org/reports/FBgn0264693 protein_coding_gene microtubule binding ; GO:0008017 | inferred from direct assay structural molecule activity ; GO:0005198 | inferred from biological aspect of ancestor with PANTHER:PTN001030845 microtubule polymerization ; GO:0046785 | inferred from mutant phenotype regulation of microtubule motor activity ; GO:2000574 | inferred from direct assay regulation of microtubule-based movement ; GO:0060632 | inferred from direct assay inferred from mutant phenotype centrosome separation ; GO:0051299 | inferred from mutant phenotype skeletal muscle fiber development ; GO:0048741 | inferred from mutant phenotype establishment of nucleus localization ; GO:0040023 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype apical part of cell ; GO:0045177 | inferred from direct assay microtubule cytoskeleton ; GO:0015630 | inferred from biological aspect of ancestor with PANTHER:PTN001030845 "ens, ensc, CG14998, Dm-308, swoosh" IPR008604:Microtubule-associated protein 7 family CG14998 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-217b7.1, Drer\map7d2a, Drer\map7d1a, Drer\map7a, Drer\si:ch73-281i18.3, Drer\map7d2b, Drer\map7d1b, Drer\map7d3" - - "Xtro\map7d1, Xtro\map7d2" "Mmus\Map7d2, Mmus\Mtap7d3, Mmus\Map7, Mmus\Map7d1" "Hsap\MAP7D3, Hsap\KIAA1211, Hsap\MAP7, Hsap\MAP7D1, Hsap\MAP7D2" FBgn0028996 onecut onecut http://flybase.org/reports/FBgn0028996 protein_coding_gene "DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001422142 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN001422142 system development ; GO:0048731 | inferred from biological aspect of ancestor with PANTHER:PTN001422142 nucleus ; GO:0005634 | inferred from direct assay "onecut, CG1922, A1" "IPR001356:Homeobox domain, IPR003350:CUT domain, IPR009057:Homeobox domain-like, IPR010982:Lambda repressor-like, DNA-binding domain" CG1922 11-Aug-17 DroID_v2017_08 "Drer\onecut3b, Drer\onecut3a, Drer\onecut2, Drer\cux2b, Drer\onecutl, Drer\cux1b, Drer\onecut1, Drer\cux2a, Drer\cux1a" Scer\COY1 "Cele\ceh-38, Cele\ceh-48, Cele\ceh-39, Cele\ceh-21, Cele\ceh-49" "Xtro\onecut1.2, Xtro\cux1, Xtro\onecut1, Xtro\cux2" "Mmus\Onecut2, Mmus\Cux1, Mmus\Onecut3, Mmus\Cux2, Mmus\Onecut1" "Hsap\ONECUT1, Hsap\ONECUT2, Hsap\CUX1, Hsap\CUX2, Hsap\ONECUT3" "viable,fertile,lethal,recessive,partially lethal - majority die,some die during pupal stage" FBgn0039835 mRpL32 mitochondrial ribosomal protein L32 http://flybase.org/reports/FBgn0039835 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049649 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049649 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049649 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001464365 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "L32, CG12220, BcDNA:LD41522, mRpL32" IPR011332:Zinc-binding ribosomal protein CG12220 11-Aug-17 DroID_v2017_08 Drer\mrpl32 Scer\MRPL32 Cele\mrpl-32 Xtro\mrpl32 Mmus\Mrpl32 Hsap\MRPL32 "viable,visible" trichogen cell DRSC14479 IE -0.17296944 2.25137822 -1.523178217 -0.117618292 -0.647544798 -0.47835507 FBgn0038586 CG7168 - http://flybase.org/reports/FBgn0038586 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7168 IPR017920:COMM domain CG7168 11-Aug-17 DroID_v2017_08 "Drer\commd5, Drer\commd2, Drer\commd9" - - "Xtro\commd9, Xtro\commd2, Xtro\commd4" "Mmus\Commd2, Mmus\Commd9" "Hsap\COMMD2, Hsap\COMMD9" viable FBgn0038381 EndoU Endoribonuclease U-specific http://flybase.org/reports/FBgn0038381 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR018998" - - "EndoU, CG3303, dendoU" IPR018998:Endoribonuclease XendoU CG3303 11-Aug-17 DroID_v2017_08 "Drer\prg4b, Drer\endou, Drer\si:dkey-222f8.3, Drer\prg4a, Drer\endouc, Drer\endou2" - "Cele\M60.2, Cele\K02A11.3" "Xtro\LOC100497154, Xtro\endou, Xtro\prg4, Xtro\endou" Mmus\Endou Hsap\ENDOU viable FBgn0023197 Jon74E Jonah 74E http://flybase.org/reports/FBgn0023197 FBgn0036737 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG6298, CT19724, SP85, Jon74E" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG6298 11-Aug-17 DroID_v2017_08 "Drer\masp2, Drer\zgc:163025" - Cele\svh-1 - "Mmus\Ctrb1, Mmus\Cela2a, Mmus\C1s2, Mmus\F9, Mmus\Ctrc, Mmus\C1s1, Mmus\Cela3a, Mmus\Cela3b, Mmus\Cela1, Mmus\Ctrl" "Hsap\C1S, Hsap\PROC, Hsap\F9" FBgn0033302 Cyp6a14 Cyp6a14 http://flybase.org/reports/FBgn0033302 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "Cyp6a14, 6a14, CG8687" "IPR001128:Cytochrome P450, IPR017972:Cytochrome P450, conserved site, IPR002401:Cytochrome P450, E-class, group I" CG8687 11-Aug-17 DroID_v2017_08 "Drer\cyp3c3, Drer\cyp3c1, Drer\cyp3c4, Drer\tbxas1, Drer\cyp3a65, Drer\cyp3c2, Drer\cyp26a1" "Scer\ERG11, Scer\ERG5" "Cele\cyp-25A6, Cele\cyp-25A1, Cele\cyp-25A4, Cele\cyp-13A1, Cele\cyp-13A3, Cele\cyp-13A7, Cele\cyp-13A8, Cele\cyp-13B2, Cele\cyp-13A12, Cele\cyp-13A2, Cele\cyp-43A1, Cele\cyp-13B1, Cele\cyp-44A1, Cele\cyp-13A11, Cele\cyp-13A4, Cele\cyp-13A10, Cele\cyp-25A2, Cele\cyp-13A5, Cele\cyp-25A3, Cele\cyp-13A6" "Xtro\tbxas1, Xtro\LOC100494419, Xtro\cyp3a5, Xtro\cyp3a4" "Mmus\Tbxas1, Mmus\Cyp3a41b, Mmus\Cyp3a13, Mmus\Cyp3a11, Mmus\Cyp3a59, Mmus\Cyp3a25, Mmus\Cyp3a41a, Mmus\Cyp3a44, Mmus\Cyp4f37, Mmus\Cyp3a57, Mmus\Cyp3a16, Mmus\Cyp26a1" "Hsap\CYP3A4, Hsap\CYP3A43, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\TBXAS1, Hsap\CYP3A7-CYP3A51P, Hsap\CYP26A1" FBgn0035189 CG9119 - http://flybase.org/reports/FBgn0035189 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from sequence or structural similarity with HGNC:30204 hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from sequence or structural similarity with HGNC:30204" biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR015021 cellular_component ; GO:0005575 | no biological data available "CT9987, CG9119" IPR015021:Domain of unknown function DUF1907 CG9119 11-Aug-17 DroID_v2017_08 Drer\zgc:85789 - Cele\C24B5.4 Xtro\c11orf54 Mmus\4931406C07Rik Hsap\C11orf54 viable FBgn0040256 Ugt86Dd Ugt86Dd http://flybase.org/reports/FBgn0040256 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG6633, AC 006491D, Ugt86Dd" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG6633 11-Aug-17 DroID_v2017_08 "Drer\ugt2a4, Drer\ugt2a3, Drer\ugt5b6, Drer\ugt1b4, Drer\ugt1ab, Drer\ugt1b2, Drer\ugt5e1, Drer\ugt5c1, Drer\ugt2b1, Drer\ugt5g2, Drer\ugt5b4, Drer\ugt5a4, Drer\ugt2a6, Drer\ugt2a2, Drer\ugt2b3, Drer\ugt8, Drer\ugt5f1, Drer\ugt1b3, Drer\ugt1b7, Drer\zgc:172315, Drer\ugt5b1, Drer\ugt1b5, Drer\ugt5d1, Drer\ugt5b3, Drer\ugt2a1, Drer\ugt5c2, Drer\ugt5g1, Drer\ugt2b5, Drer\ugt5a2, Drer\ugt2b6, Drer\ugt5a5, Drer\ugt5a1, Drer\ugt5c3, Drer\ugt2a5, Drer\ugt5b2" Scer\ATG26 "Cele\ugt-1, Cele\ugt-36, Cele\ugt-41, Cele\ugt-59, Cele\ugt-58, Cele\ugt-37, Cele\C55H1.1, Cele\C23G10.6, Cele\ugt-46, Cele\ugt-5, Cele\ugt-62, Cele\ugt-61, Cele\ugt-27, Cele\ugt-60, Cele\C03A7.13, Cele\ugt-15, Cele\ugt-4, Cele\ugt-13, Cele\ugt-16, Cele\ugt-65, Cele\ugt-43, Cele\ugt-45, Cele\ugt-11, Cele\ugt-33, Cele\ugt-7, Cele\C03A7.12, Cele\ugt-21, Cele\ugt-44, Cele\ugt-28, Cele\ugt-53, Cele\ugt-50, Cele\ugt-2, Cele\ugt-9, Cele\ugt-22, Cele\ugt-55, Cele\F54C1.1, Cele\ugt-39, Cele\F10D2.8, Cele\ugt-56, Cele\ugt-49, Cele\ugt-29, Cele\ugt-47, Cele\ugt-6, Cele\ugt-25, Cele\ugt-3, Cele\H23N18.4, Cele\ugt-8, Cele\ugt-35, Cele\ugt-10, Cele\ugt-32, Cele\ugt-14, Cele\ugt-26, Cele\ugt-12, Cele\ugt-34, Cele\ugt-52, Cele\ugt-31, Cele\Y43D4A.2, Cele\ugt-17, Cele\ugt-57, Cele\ugt-19, Cele\ugt-54, Cele\ugt-51, Cele\ugt-23, Cele\ugt-30, Cele\ugt-42, Cele\ugt-38, Cele\ugt-48, Cele\ugt-20, Cele\K04A8.10, Cele\ugt-40, Cele\ugt-24, Cele\ugt-18" "Xtro\ugt1a6, Xtro\ugt8, Xtro\ugt2b4, Xtro\ugt3a2, Xtro\ugt2a1" "Mmus\Ugt2b5, Mmus\Ugt3a2, Mmus\Ugt2b37, Mmus\Ugt1a1, Mmus\Ugt8a, Mmus\Ugt3a1, Mmus\Ugt1a7c, Mmus\Ugt1a5, Mmus\Ugt2b34, Mmus\Ugt2a3, Mmus\Ugt2a1, Mmus\Ugt1a6b, Mmus\Ugt2b35, Mmus\Ugt1a2, Mmus\Ugt2b36, Mmus\Ugt2b1, Mmus\Ugt2a2, Mmus\Ugt1a10, Mmus\Ugt2b38, Mmus\Ugt1a9" "Hsap\UGT1A7, Hsap\UGT2B4, Hsap\UGT1A3, Hsap\UGT8, Hsap\UGT1A10, Hsap\UGT1A1, Hsap\UGT1A8, Hsap\UGT2B11, Hsap\UGT1A5, Hsap\UGT1A4, Hsap\UGT2B17, Hsap\UGT3A1, Hsap\UGT2A2, Hsap\UGT2B7, Hsap\UGT2B28, Hsap\UGT2A3, Hsap\UGT2B10, Hsap\UGT2B15, Hsap\UGT1A6, Hsap\UGT3A2, Hsap\UGT1A9" viable FBgn0053857 His3:CG33857 His3:CG33857 http://flybase.org/reports/FBgn0053857 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33857, His3:CG33857" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33857 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-429i10.3, Drer\LOC108190747, Drer\h3f3d, Drer\zgc:113984, Drer\zgc:173552, Drer\si:ch73-36p18.2, Drer\zgc:113983, Drer\hist2h3ca1, Drer\hist2h3c, Drer\LOC108190746, Drer\h3f3a, Drer\cenpa, Drer\h3f3b.1, Drer\h3f3c" "Scer\CSE4, Scer\HHT1, Scer\HHT2" "Cele\his-9, Cele\his-32, Cele\his-2, Cele\his-6, Cele\his-45, Cele\his-69, Cele\his-27, Cele\his-25, Cele\his-17, Cele\his-72, Cele\his-74, Cele\his-49, Cele\his-55, Cele\his-63, Cele\his-42, Cele\his-13, Cele\his-59, Cele\his-71" "Xtro\cenpa, Xtro\hist2h3d, Xtro\LOC101730642, Xtro\h3f3b" "Mmus\Hist1h3c, Mmus\Hist2h3c2, Mmus\H3f3b, Mmus\Hist1h3a, Mmus\Hist1h3h, Mmus\Hist1h3g, Mmus\Hist1h3i, Mmus\Hist1h3f, Mmus\Hist1h3b, Mmus\Hist2h3c1, Mmus\Cenpa, Mmus\Hist1h3d, Mmus\Hist2h3b, Mmus\H3f3a, Mmus\Hist1h3e" "Hsap\HIST1H3E, Hsap\HIST2H3C, Hsap\H3F3C, Hsap\H3F3A, Hsap\HIST1H3J, Hsap\HIST2H3D, Hsap\HIST1H3C, Hsap\H3F3B, Hsap\HIST1H3H, Hsap\HIST1H3D, Hsap\HIST2H3A, Hsap\HIST1H3F, Hsap\HIST1H3B, Hsap\HIST1H3I, Hsap\HIST1H3G, Hsap\HIST1H3A, Hsap\CENPA, Hsap\HIST3H3" FBgn0040251 Ugt86Di Ugt86Di http://flybase.org/reports/FBgn0040251 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "Ugt86Di, CG6658, AC 006491I" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG6658 11-Aug-17 DroID_v2017_08 "Drer\ugt2b6, Drer\zgc:172315, Drer\ugt2b1, Drer\ugt1b7, Drer\ugt1ab, Drer\ugt1b2, Drer\ugt5g1, Drer\ugt2a6, Drer\ugt1b3, Drer\ugt5e1, Drer\ugt1b5, Drer\ugt2b5, Drer\ugt2b3, Drer\ugt5a4, Drer\ugt5b1, Drer\ugt8, Drer\ugt5a1, Drer\ugt5c1, Drer\ugt5f1, Drer\ugt2a2, Drer\ugt5c2, Drer\ugt5b4, Drer\ugt5a2, Drer\ugt5b3, Drer\ugt5g2, Drer\ugt5b2, Drer\ugt5d1, Drer\ugt2a5, Drer\ugt5b6, Drer\ugt5c3, Drer\ugt1b4, Drer\ugt5a5" Scer\ATG26 "Cele\ugt-33, Cele\ugt-21, Cele\ugt-25, Cele\ugt-37, Cele\ugt-3, Cele\ugt-9, Cele\ugt-49, Cele\ugt-24, Cele\ugt-1, Cele\ugt-7, Cele\ugt-4, Cele\ugt-53, Cele\ugt-17, Cele\ugt-40, Cele\ugt-41, Cele\ugt-36, Cele\ugt-13, Cele\ugt-28, Cele\ugt-44, Cele\ugt-46, Cele\ugt-51, Cele\ugt-18, Cele\C03A7.12, Cele\ugt-27, Cele\ugt-14, Cele\ugt-26, Cele\Y43D4A.2, Cele\ugt-48, Cele\ugt-2, Cele\ugt-10, Cele\ugt-65, Cele\ugt-12, Cele\ugt-59, Cele\ugt-35, Cele\ugt-39, Cele\ugt-38, Cele\ugt-60, Cele\ugt-5, Cele\C23G10.6, Cele\C03A7.13, Cele\ugt-50, Cele\ugt-54, Cele\ugt-52, Cele\ugt-47, Cele\ugt-15, Cele\ugt-22, Cele\ugt-23, Cele\C55H1.1, Cele\F10D2.8, Cele\ugt-61, Cele\ugt-43, Cele\ugt-20, Cele\ugt-57, Cele\ugt-31, Cele\ugt-56, Cele\ugt-19, Cele\ugt-62, Cele\ugt-55, Cele\H23N18.4, Cele\ugt-6, Cele\K04A8.10, Cele\ugt-29, Cele\ugt-32, Cele\ugt-30, Cele\ugt-58, Cele\F54C1.1, Cele\ugt-11, Cele\ugt-42, Cele\ugt-8, Cele\ugt-45, Cele\ugt-34, Cele\ugt-16" "Xtro\ugt8, Xtro\ugt2a1, Xtro\ugt1a1, Xtro\ugt2b4, Xtro\ugt1a6, Xtro\ugt3a2" "Mmus\Ugt1a6b, Mmus\Ugt2b5, Mmus\Ugt1a1, Mmus\Ugt1a5, Mmus\Ugt2b1, Mmus\Ugt2b38, Mmus\Ugt2b35, Mmus\Ugt1a10, Mmus\Ugt2a1, Mmus\Ugt2b37, Mmus\Ugt2b36, Mmus\Ugt2a2, Mmus\Ugt1a9, Mmus\Ugt3a2, Mmus\Ugt8a, Mmus\Ugt2b34, Mmus\Ugt2a3, Mmus\Ugt1a7c, Mmus\Ugt3a1, Mmus\Ugt1a2" "Hsap\UGT2B17, Hsap\UGT1A10, Hsap\UGT3A1, Hsap\UGT1A6, Hsap\UGT2B4, Hsap\UGT2B7, Hsap\UGT2B11, Hsap\UGT1A7, Hsap\UGT1A4, Hsap\UGT2B10, Hsap\UGT2B15, Hsap\UGT2A3, Hsap\UGT2A2, Hsap\UGT1A1, Hsap\UGT2B28, Hsap\UGT1A5, Hsap\UGT3A2, Hsap\UGT1A3, Hsap\UGT8, Hsap\UGT1A9, Hsap\UGT1A8" viable FBgn0053910 His2B:CG33910 His2B:CG33910 http://flybase.org/reports/FBgn0053910 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33910, His2B:CG33910" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33910 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-23a13.16, Drer\LOC100334869, Drer\si:dkey-108k21.11, Drer\si:ch73-368j24.8, Drer\si:ch211-113a14.28, Drer\si:dkey-261m9.19, Drer\zgc:194989, Drer\si:ch211-113a14.29, Drer\LOC100329560, Drer\si:dkey-261m9.6, Drer\ano9a, Drer\zgc:173587, Drer\hist1h2ba, Drer\LOC100334559, Drer\si:ch73-36p18.3, Drer\si:ch1073-159d7.5, Drer\LOC100329290, Drer\hist2h2l, Drer\si:dkey-23a13.1, Drer\zgc:92591, Drer\si:ch211-113a14.11, Drer\si:ch1073-159d7.13, Drer\zgc:114046, Drer\si:dkey-108k21.27" "Scer\HTB2, Scer\HTB1" "Cele\his-11, Cele\his-8, Cele\his-29, Cele\his-15, Cele\his-62, Cele\his-54, Cele\his-58, Cele\his-4, Cele\his-44, Cele\his-34, Cele\his-39, Cele\his-52, Cele\his-48, Cele\his-22, Cele\his-41, Cele\his-20, Cele\his-66" "Xtro\LOC100486870, Xtro\LOC100497082, Xtro\LOC101734494, Xtro\LOC100497915, Xtro\LOC101735218, Xtro\LOC100496445, Xtro\LOC101733489, Xtro\LOC100498072, Xtro\LOC100498553, Xtro\LOC100492632, Xtro\LOC101735164, Xtro\LOC100498329, Xtro\LOC100495041, Xtro\LOC100485294, Xtro\LOC101731067, Xtro\hist1h2bm, Xtro\LOC100485134, Xtro\LOC100495396, Xtro\LOC100487485, Xtro\LOC100495578, Xtro\hist2h2be, Xtro\LOC101733828, Xtro\LOC100496436, Xtro\LOC100486150, Xtro\LOC100495415, Xtro\LOC101734862, Xtro\hist1h2bk, Xtro\hist1h2bj, Xtro\LOC100496181, Xtro\LOC101731959, Xtro\LOC101733171, Xtro\LOC101731852, Xtro\LOC100498647, Xtro\LOC101730940" "Mmus\Hist1h2br, Mmus\Hist1h2ba, Mmus\Hist3h2ba, Mmus\Hist1h2bg, Mmus\Hist1h2bb, Mmus\Hist1h2bf, Mmus\Hist1h2bm, Mmus\Hist1h2bq, Mmus\1700024P04Rik, Mmus\Hist2h2be, Mmus\Hist1h2bk, Mmus\Hist1h2bl, Mmus\Hist1h2be, Mmus\Hist1h2bp, Mmus\Hist1h2bc, Mmus\H2bfm, Mmus\Hist1h2bj, Mmus\Hist2h2bb, Mmus\Hist1h2bn, Mmus\Hist1h2bh" "Hsap\HIST1H2BA, Hsap\HIST1H2BM, Hsap\HIST1H2BD, Hsap\HIST1H2BK, Hsap\HIST1H2BN, Hsap\HIST1H2BB, Hsap\H2BFM, Hsap\HIST3H2BB, Hsap\H2BFWT, Hsap\HIST2H2BF, Hsap\HIST1H2BI, Hsap\HIST1H2BH, Hsap\HIST1H2BG, Hsap\HIST1H2BL, Hsap\HIST1H2BE, Hsap\HIST1H2BF, Hsap\HIST1H2BC, Hsap\HIST1H2BO, Hsap\HIST1H2BJ, Hsap\HIST2H2BE" FBgn0031619 CG3355 - http://flybase.org/reports/FBgn0031619 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP21, CG3355" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG3355 11-Aug-17 DroID_v2017_08 "Drer\prss60.2, Drer\si:dkey-238d18.3, Drer\ovch1, Drer\si:dkey-16l2.17, Drer\zgc:92313, Drer\ctrb1, Drer\LOC562139, Drer\si:ch211-165b19.5, Drer\ctrl, Drer\zgc:92745, Drer\zgc:112160, Drer\zgc:112038, Drer\zgc:92511, Drer\zgc:123295, Drer\zgc:165423, Drer\tmprss3a, Drer\gzm3, Drer\ela2, Drer\zgc:112302, Drer\zgc:153968, Drer\tmprss4b, Drer\zgc:92590, Drer\prss60.1, Drer\si:ch211-165b19.9, Drer\pamr1, Drer\si:dkeyp-93a5.3, Drer\cfd, Drer\try, Drer\zgc:112368, Drer\gzma, Drer\prss60.3, Drer\si:ch211-165b19.8, Drer\zgc:163079, Drer\zgc:92041, Drer\ela3l, Drer\si:dkeyp-93a5.2, Drer\zgc:154142, Drer\gzmk, Drer\LOC100004427, Drer\si:dkey-57c15.4, Drer\zgc:171592, Drer\ela2l, Drer\zgc:112285" - "Cele\svh-1, Cele\try-4, Cele\try-1, Cele\try-6" "Xtro\LOC100135144, Xtro\prss29, Xtro\mst1, Xtro\cela3a, Xtro\ctrb1, Xtro\cela2a, Xtro\tmprss3, Xtro\ctrb2" "Mmus\Try4, Mmus\Tmprss5, Mmus\Cela3b, Mmus\2210010C04Rik, Mmus\Tmprss3, Mmus\Cela3a, Mmus\Klk15, Mmus\Gm5771, Mmus\Ctrl, Mmus\Ctrc, Mmus\Gm10334, Mmus\Hpn, Mmus\Cela2a, Mmus\Prss34, Mmus\Prss1, Mmus\Prss3, Mmus\Tmprss15, Mmus\Prss2, Mmus\Acr, Mmus\Cela1, Mmus\Tmprss6, Mmus\Ctrb1, Mmus\Klk9, Mmus\Mst1, Mmus\Try10, Mmus\Tmprss2" "Hsap\TMPRSS5, Hsap\MST1, Hsap\CELA3B, Hsap\PRSS1, Hsap\CTRB1, Hsap\KLK9, Hsap\KLK15, Hsap\CELA1, Hsap\TMPRSS6, Hsap\CTRB2, Hsap\TMPRSS2, Hsap\ACR, Hsap\MST1L, Hsap\CTRC, Hsap\CELA2A, Hsap\CELA3A, Hsap\HGF, Hsap\CELA2B, Hsap\TMPRSS15, Hsap\PRSS3, Hsap\TMPRSS3, Hsap\CTRL, Hsap\HPN" viable FBgn0036374 Spt20 Spt20 http://flybase.org/reports/FBgn0036374 protein_coding_gene transcription cofactor activity ; GO:0003712 | inferred from sequence or structural similarity with SGD:S000005508 histone acetylation ; GO:0016573 | inferred from sequence or structural similarity with SGD:S000005508 SAGA complex ; GO:0000124 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay SAGA-type complex ; GO:0070461 | inferred from direct assay "Spt20, CG17689, lincRNA.S5070" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR021950:Transcription factor Spt20" CG17689 11-Aug-17 DroID_v2017_08 Drer\supt20 - - - Mmus\Supt20 "Hsap\SUPT20H, Hsap\SUPT20HL1, Hsap\SUPT20HL2" DRSC25791 K 0.752675837 1.67752533 FBgn0035006 CG4563 - http://flybase.org/reports/FBgn0035006 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG4563 "IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase" CG4563 11-Aug-17 DroID_v2017_08 "Drer\acsbg1, Drer\acsf3" "Scer\PCS60, Scer\HSP26" "Cele\mec-18, Cele\acs-14, Cele\C25G6.3, Cele\acs-6, Cele\acs-9, Cele\C32E8.6, Cele\acs-10, Cele\acs-7" Xtro\acsf3 "Mmus\Acsf3, Mmus\Acsbg1, Mmus\Fadd" "Hsap\ACSF3, Hsap\ACSBG1, Hsap\FADD" "partially lethal - majority die,some die during pupal stage" DRSC04474 K 1.094311827 -0.061981309 -0.530343507 0.160483336 -0.178957442 -1.96848261 FBgn0032705 Grip71 Grip71 http://flybase.org/reports/FBgn0032705 protein_coding_gene gamma-tubulin binding ; GO:0043015 | inferred from direct assay bicoid mRNA localization ; GO:0045450 | NOT inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype spindle assembly involved in female meiosis I ; GO:0007057 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype gamma-tubulin ring complex ; GO:0008274 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Grip71, Dgrip71, Dgp71WD, CG10346, Grip71wd" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat" CG10346 11-Aug-17 DroID_v2017_08 "Drer\nedd1, Drer\grwd1" "Scer\UME1, Scer\WTM1, Scer\RRB1, Scer\WTM2" Cele\Y54H5A.1 Xtro\nedd1 "Mmus\Nedd1, Mmus\Grwd1" "Hsap\NEDD1, Hsap\GRWD1" "viable,female sterile,male fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,mitotic cell cycle defective" "meiotic spindleED119),S2 cell-line,spindle,neuroblast" DRSC02042 IE 2.396538247 1.170734939 2.04178651 0.545331882 -0.677153768 -1.39127762 FBgn0262517 Ltn1 Listerin E3 ubiquitin protein ligase 1 http://flybase.org/reports/FBgn0262517 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model sleep ; GO:0030431 | inferred from expression pattern ribosome-associated ubiquitin-dependent protein catabolic process ; GO:1990116 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG32210, Ltn1, l(3)76BDr, CG9274, CG9268" "IPR001841:Zinc finger, RING-type, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG32210 11-Aug-17 DroID_v2017_08 Drer\si:dkey-175g6.5 Scer\RKR1 "Cele\F57C12.2, Cele\Y54E10A.11" Xtro\ltn1 Mmus\Ltn1 Hsap\LTN1 DRSC11056 IE 1.576156961 0.148107878 1.563090841 -0.508509457 -0.195393408 -0.132806523 FBgn0004655 wapl wings apart-like http://flybase.org/reports/FBgn0004655 "FBgn0001396, FBgn0004001" protein_coding_gene molecular_function ; GO:0003674 | no biological data available female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype mitotic sister chromatid cohesion ; GO:0007064 | inferred from biological aspect of ancestor with PANTHER:PTN000499022 sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype regulation of cohesin loading ; GO:0071922 | inferred from biological aspect of ancestor with PANTHER:PTN000499022 regulation of chromosome condensation ; GO:0060623 | inferred from biological aspect of ancestor with PANTHER:PTN000499022 mitotic cohesin unloading ; GO:0061781 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "EG:87B1.2, CG3707, l74, pasc, RNA D, l(1)C204, N2, l(1)2Df, l(1)2Dd, RNAD, C204, wap, l(1)N5[72], l(1)N2, wapl, Wapl" "IPR012502:WAPL domain, IPR016024:Armadillo-type fold, IPR022771:Wings apart-like protein, IPR011989:Armadillo-like helical" CG3707 11-Aug-17 DroID_v2017_08 "Drer\wapla, Drer\waplb" - Cele\wapl-1 Xtro\wapl Mmus\Wapl Hsap\WAPL embryonic stage "lethal,recessive,some die during second instar larval stage,partially lethal - majority die,visible,suppressor of variegation,dominant,non-suppressor of variegation,non-enhancer of variegation,enhancer of variegation,germline clone,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,meiotic cell cycle defective,viable,wild-type,lethal - all die before end of pupal stage,some die during pupal stage,planar polarity defective" "tergite,wing vein,eye,wing,pre-blastoderm embryo,germline clone,maternal effect,heterochromatin | maternal effect,metaphase & condensed nuclear chromosome | maternal effect,sex comb,ectopic,adult abdomen,posterior,sternopleural bristle,male genitalia" DRSC27941 K -0.157093315 1.062571687 -0.104295441 0.545147092 -0.031255945 2.025374172 FBgn0034165 CG6435 - http://flybase.org/reports/FBgn0034165 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR008597 - - CG6435 "IPR008597:Destabilase, IPR023346:Lysozyme-like domain" CG6435 11-Aug-17 DroID_v2017_08 - - "Cele\ilys-6, Cele\ilys-3, Cele\ilys-4, Cele\ilys-5, Cele\ilys-2, Cele\ilys-1" - - - viable DRSC06987 E -0.199253084 0.573510965 1.771714389 0.607539304 -0.440522651 -0.372546919 FBgn0035915 S-Lap1 Sperm-Leucylaminopeptidase 1 http://flybase.org/reports/FBgn0035915 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283 mushroom body development ; GO:0016319 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "bs34e01.y1, bs33g03.y1, anon-WO0140519.89, S-Lap1, CG6372, S-LAP 1" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG6372 11-Aug-17 DroID_v2017_08 "Drer\rfwd2, Drer\npepl1, Drer\lap3, Drer\zgc:152830" - "Cele\lap-1, Cele\lap-2" "Xtro\lap3, Xtro\rfwd2" "Mmus\Lap3, Mmus\Rfwd2, Mmus\Npepl1" "Hsap\NPEPL1, Hsap\LAP3" neuroanatomy defective adult mushroom body DRSC10627 K 0.105527723 -0.420773433 0.093738646 -0.205905885 -1.515295161 -0.717908564 FBgn0264908 pHCl-1 pH-sensitive chloride channel 1 http://flybase.org/reports/FBgn0264908 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 chloride channel activity ; GO:0005254 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype chloride transport ; GO:0006821 | inferred from direct assay "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201" "CG33989, pHCl, CG44099, BP1024, BcDNA:GH21757, CG6112, CG13444, pHCL-A, CT19189, CG12486, pHCl-1" "IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain" CG44099 11-Aug-17 DroID_v2017_08 "Drer\glrbb, Drer\glra4a, Drer\glra2, Drer\glra4b, Drer\glra3, Drer\glrba, Drer\glra1" - "Cele\glc-1, Cele\avr-15, Cele\glc-4, Cele\glc-3, Cele\avr-14, Cele\lgc-34, Cele\glc-2" Xtro\glrb "Mmus\Glra2, Mmus\Glra4, Mmus\Glrb, Mmus\Glra1, Mmus\Glra3" "Hsap\GLRA3, Hsap\HTR3E, Hsap\GLRB, Hsap\GLRA4, Hsap\GLRA1, Hsap\GLRA2" DRSC09991 I 1.519967521 0.095913365 0.008321837 -0.370159769 -0.540510463 0.300037569 FBgn0053896 His2B:CG33896 His2B:CG33896 http://flybase.org/reports/FBgn0053896 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33896, His2B:CG33896" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33896 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113a14.29, Drer\hist2h2l, Drer\si:dkey-261m9.19, Drer\zgc:92591, Drer\si:ch73-368j24.8, Drer\si:dkey-108k21.27, Drer\zgc:194989, Drer\si:ch1073-153i20.3, Drer\LOC100334559, Drer\si:dkey-108k21.11, Drer\zgc:173587, Drer\si:ch1073-159d7.13, Drer\si:dkey-261m9.6, Drer\LOC100329560, Drer\zgc:114046, Drer\si:ch1073-159d7.5, Drer\LOC100334869, Drer\ano9a, Drer\LOC100329290, Drer\si:dkey-23a13.16, Drer\si:ch211-113a14.11, Drer\si:ch73-36p18.3, Drer\si:dkey-23a13.5, Drer\zgc:173585, Drer\si:dkey-23a13.1, Drer\si:ch211-113a14.28, Drer\hist1h2ba" "Scer\HTB1, Scer\HTB2" "Cele\his-8, Cele\his-52, Cele\his-4, Cele\his-62, Cele\his-29, Cele\his-41, Cele\his-22, Cele\his-39, Cele\his-11, Cele\his-15, Cele\his-34, Cele\his-66, Cele\his-20, Cele\his-54, Cele\his-58, Cele\his-44, Cele\his-48" "Xtro\hist1h2bj, Xtro\LOC101734862, Xtro\LOC101731959, Xtro\LOC101730940, Xtro\LOC100492632, Xtro\LOC101733171, Xtro\LOC100495041, Xtro\LOC100498329, Xtro\LOC100496436, Xtro\LOC100497915, Xtro\LOC101731852, Xtro\LOC100498553, Xtro\LOC101731067, Xtro\LOC100485294, Xtro\LOC100498072, Xtro\hist2h2be, Xtro\hist1h2bk, Xtro\LOC100486870, Xtro\LOC100498647, Xtro\LOC100485134, Xtro\LOC101733828, Xtro\LOC100496445, Xtro\LOC100495578, Xtro\LOC100487485, Xtro\LOC101733489, Xtro\LOC100486150, Xtro\LOC101735218, Xtro\LOC100495396, Xtro\LOC100495415, Xtro\LOC100496181, Xtro\LOC101735164, Xtro\LOC101734494, Xtro\hist1h2bm, Xtro\LOC100497082" "Mmus\Hist1h2bn, Mmus\1700024P04Rik, Mmus\Hist1h2bl, Mmus\Hist1h2ba, Mmus\Hist2h2be, Mmus\Hist1h2bf, Mmus\Hist1h2be, Mmus\Hist1h2br, Mmus\H2bfm, Mmus\Hist2h2bb, Mmus\Hist1h2bk, Mmus\Hist1h2bg, Mmus\Hist1h2bm, Mmus\Hist3h2ba, Mmus\Hist1h2bc, Mmus\Hist1h2bp, Mmus\Hist1h2bj, Mmus\Hist1h2bb, Mmus\Hist1h2bh, Mmus\Hist1h2bq" "Hsap\HIST1H2BG, Hsap\HIST1H2BK, Hsap\HIST2H2BE, Hsap\H2BFWT, Hsap\HIST2H2BF, Hsap\HIST1H2BD, Hsap\HIST1H2BA, Hsap\HIST3H2BB, Hsap\HIST1H2BB, Hsap\H2BFM, Hsap\HIST1H2BF, Hsap\HIST1H2BE, Hsap\HIST1H2BL, Hsap\HIST1H2BO, Hsap\HIST1H2BC, Hsap\HIST1H2BI, Hsap\HIST1H2BM, Hsap\HIST1H2BN, Hsap\HIST1H2BH, Hsap\HIST1H2BJ" FBgn0034051 Mlf Myelodysplasia/myeloid leukemia factor http://flybase.org/reports/FBgn0034051 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype regulation of cell proliferation involved in compound eye morphogenesis ; GO:2000495 | inferred from expression pattern protein stabilization ; GO:0050821 | inferred from mutant phenotype" polytene chromosome interband ; GO:0005705 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "dmlf, dMLF, CG8295, BcDNA:SD18148, Mlf, MLF, mlf" IPR019376:Myeloid leukemia factor CG8295 11-Aug-17 DroID_v2017_08 "Drer\mlf1, Drer\mlf2" - Cele\Y17G7B.17 Xtro\mlf2 "Mmus\Mlf2, Mmus\Mlf1" "Hsap\MLF2, Hsap\MLF1" "wild-type,visible,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage,lethal,heat sensitive,increased cell death,melanotic necrosis,eye color defective" "interocellar bristle,head bristle,wing vein,ectopic,crystal cell,2nd posterior cell,anterior crossvein,scutellar bristle,wing margin,wing,posterior compartment,wing disc,ommatidium,interommatidial bristle,eye,pigment cell" DRSC07472 IEK 4.204039884 3.75936023 8.161599187 -1.083441085 -0.674976756 1.542831348 FBgn0052533 CG32533 - http://flybase.org/reports/FBgn0052533 protein_coding_gene helicase activity ; GO:0004386 | inferred from sequence or structural similarity with SGD:S000004802 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "CG12211, cg12211, CG14198, CG32533" "IPR001650:Helicase, C-terminal, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain" CG32533 11-Aug-17 DroID_v2017_08 "Drer\dhx33, Drer\dhx40, Drer\dhx8, Drer\mrps14, Drer\dhx34" "Scer\DHR2, Scer\PRP22, Scer\MRP2" Cele\smgl-2 "Xtro\dhx8, Xtro\dhx33, Xtro\dhx40, Xtro\mrps14, Xtro\ythdc2, Xtro\dhx34" "Mmus\Dhx33, Mmus\Dhx40, Mmus\Dhx8, Mmus\Mrps14, Mmus\Ythdc2, Mmus\Dhx34" "Hsap\DHX8, Hsap\MRPS14, Hsap\DHX33, Hsap\DHX34, Hsap\YTHDC2, Hsap\DHX40" "viable,fertile" FBgn0040028 CG17450 - http://flybase.org/reports/FBgn0040028 protein_coding_gene - sperm competition ; GO:0046692 | inferred from mutant phenotype - CG17450 IPR000435:Tektin CG17450 11-Aug-17 DroID_v2017_08 "Drer\tekt1, Drer\tekt3, Drer\tekt4, Drer\tekt2" Scer\SPC110 Cele\R02E12.4 "Xtro\tekt2, Xtro\tekt3, Xtro\tekt4, Xtro\tekt1" "Mmus\Tekt1, Mmus\Tekt4, Mmus\Tekt5, Mmus\Tekt3, Mmus\Tekt2" "Hsap\TEKT1, Hsap\TEKT5, Hsap\TEKT4, Hsap\TEKT2, Hsap\TEKT3" FBgn0035065 CG3589 - http://flybase.org/reports/FBgn0035065 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence or structural similarity with HGNC:28531 serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN000470278 protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000470278 regulation of fatty acid beta-oxidation ; GO:0031998 | inferred from biological aspect of ancestor with PANTHER:PTN001077148 proteolysis ; GO:0006508 | inferred from sequence or structural similarity with HGNC:28531 peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000470278 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:28531 inferred from sequence model CG3589 "IPR009003:Peptidase S1, PA clan" CG3589 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-33c12.2, Drer\si:dkey-33c12.10, Drer\LOC100000024, Drer\LOC799006, Drer\si:dkey-84o3.2, Drer\si:busm1-sl7.7, Drer\tysnd1, Drer\si:dkey-84o3.7, Drer\LOC100003308, Drer\htra3b, Drer\si:dkey-19p15.4, Drer\htra4, Drer\si:dkey-84o3.3, Drer\htra1b, Drer\LOC793110, Drer\zgc:173425, Drer\LOC797799, Drer\LOC100331049, Drer\htra1a" - - "Xtro\htra1, Xtro\tysnd1, Xtro\htra4" "Mmus\Tysnd1, Mmus\Htra2, Mmus\Htra4, Mmus\Htra3, Mmus\Htra1" "Hsap\HTRA4, Hsap\HTRA2, Hsap\HTRA3, Hsap\TYSND1, Hsap\HTRA1" "viable,fertile" FBgn0039732 CG15525 - http://flybase.org/reports/FBgn0039732 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD23244, CG15525" "IPR013169:mRNA splicing factor, Cwf18" CG15525 11-Aug-17 DroID_v2017_08 Drer\ccdc12 - Cele\Y69A2AR.21 Xtro\ccdc12 Mmus\Ccdc12 Hsap\CCDC12 DRSC15062 K -0.447038015 1.459494306 0.444748263 -0.116245676 -2.144548309 0.297137624 FBgn0040340 TRAM TRAM http://flybase.org/reports/FBgn0040340 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006634 lipid particle ; GO:0005811 | inferred from direct assay "CG11642, CG18830, EG:BACR7A4.5, TRAM" "IPR006634:TRAM/LAG1/CLN8 homology domain, IPR013599:TRAM1-like protein, IPR016447:Translocation associated membrane protein" CG11642 11-Aug-17 DroID_v2017_08 "Drer\tram2, Drer\tram1, Drer\zgc:113278" "Scer\LAC1, Scer\LAG1" "Cele\hyl-2, Cele\tram-1" "Xtro\tram2, Xtro\tram1" "Mmus\Tram1, Mmus\Tram2, Mmus\Tram1l1" "Hsap\TRAM1L1, Hsap\TRAM1, Hsap\TRAM2" viable FBgn0010225 Gel Gelsolin http://flybase.org/reports/FBgn0010225 "FBan0001106, FBgn0037221" protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR007122 actin binding ; GO:0003779 | inferred from sequence or structural similarity phagocytosis ; GO:0006909 | inferred from mutant phenotype actin filament polymerization ; GO:0030041 | inferred from sequence or structural similarity with UniProtKB:P06396 extracellular region ; GO:0005576 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay actin filament ; GO:0005884 | inferred from direct assay "CG1106, gel, DGS, Gel" "IPR007122:Villin/Gelsolin, IPR007123:Gelsolin-like domain, IPR029006:ADF-H/Gelsolin-like domain" CG1106 11-Aug-17 DroID_v2017_08 "Drer\capga, Drer\capgb, Drer\vill, Drer\avil, Drer\gsna, Drer\scinlb, Drer\scin, Drer\scinla, Drer\gsnb, Drer\vil1" - Cele\gsnl-1 "Xtro\avil, Xtro\scin, Xtro\vil1, Xtro\capg, Xtro\vill, Xtro\gsn" "Mmus\Vill, Mmus\Capg, Mmus\Gsn, Mmus\Avil, Mmus\Vil1, Mmus\Scin" "Hsap\VILL, Hsap\GSN, Hsap\VIL1, Hsap\SCIN, Hsap\AVIL, Hsap\CAPG" "partially lethal - majority die,some die during pupal stage" "adult brain,mitochondrionelav.PU" FBgn0005695 gcl germ cell-less http://flybase.org/reports/FBgn0005695 FBgn0004886 protein_coding_gene - "pole plasm assembly ; GO:0007315 | non-traceable author statement pole cell formation ; GO:0007279 | traceable author statement negative regulation of transcription from RNA polymerase III promoter ; GO:0016480 | inferred from mutant phenotype pole cell fate determination ; GO:0007278 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement" nucleus ; GO:0005634 | traceable author statement nuclear pore ; GO:0005643 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN001145256 nuclear periphery ; GO:0034399 | inferred from direct assay "GCL, gcl-1, CG8411, gcl, Gcl" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG8411 11-Aug-17 DroID_v2017_08 "Drer\btbd16, Drer\gmcl1" - Cele\gcl-1 Xtro\gmcl1 "Mmus\Gm14345, Mmus\Gm2964, Mmus\Gm2913, Mmus\Gm2825, Mmus\Gmcl1, Mmus\Gm14346, Mmus\Gmcl1l, Mmus\Gm21657, Mmus\Gm3701, Mmus\Gm21950, Mmus\Gm2777, Mmus\Gm14374, Mmus\Gm3750, Mmus\Gm21608, Mmus\Gm21645, Mmus\Gm10922, Mmus\Gm10921, Mmus\Gm2863, Mmus\Btbd16, Mmus\Gm2784, Mmus\Gm2799, Mmus\Gm14347, Mmus\Gm3706, Mmus\Gm3763, Mmus\Gm2933, Mmus\Klhl10, Mmus\Gm21951, Mmus\Gm2927, Mmus\Gm21681, Mmus\Gm21699, Mmus\Gm14351, Mmus\Gm21447" "Hsap\KLHL10, Hsap\BTBD16, Hsap\GMCL1" " embryonic stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage | stage >S11 , embryonic stage | early , adult stage && oogenesis stage | stage S8-10 , adult stage && oogenesis stage | stage S10 " " embryonic/larval foregut

, ovary

, oocyte | posterior

, embryonic/larval hindgut

, pole cell

, nurse cell

, embryonic central nervous system | restricted

, larval muscle system

, oocyte

" embryonic stage pole cell

"viable,fertile,wild-type,sterile,female semi-sterile,maternal effect,meiotic cell cycle defective,decreased cell number" "pole cell,ectopic,pole bud & nucleus,maternal effect,pole bud,germline cell" DRSC07623 E 0.41098917 -0.116359899 -1.762472348 -0.332160813 -0.235853333 0.286612685 FBgn0020304 drongo drongo http://flybase.org/reports/FBgn0020304 - protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 GTPase activator activity ; GO:0005096 | inferred from sequence model regulation of GTPase activity ; GO:0043087 | inferred from sequence model membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:5177 "CG3365, drongo, DRONGO" IPR001164:Arf GTPase activating protein CG3365 11-Aug-17 DroID_v2017_08 "Drer\zgc:114045, Drer\agfg1a, Drer\agfg1b" "Scer\AGE2, Scer\GTS1" - Xtro\agfg1 "Mmus\Agfg2, Mmus\Agfg1" "Hsap\AGFG2, Hsap\AGFG1" "partially lethal - majority die,some die during pupal stage" FBgn0033994 CG7544 - http://flybase.org/reports/FBgn0033994 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002052 23S rRNA (adenine(1618)-N(6))-methyltransferase activity ; GO:0052907 | inferred from biological aspect of ancestor with PANTHER:PTN000333539 rRNA base methylation ; GO:0070475 | inferred from biological aspect of ancestor with PANTHER:PTN000333539 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000333540 CG7544 "IPR002052:DNA methylase, N-6 adenine-specific, conserved site, IPR010286:Ribosomal RNA large subunit methyltransferase F-like, IPR017182:S-adenosyl-L-methionine dependent methyltransferase, Mett10D, predicted, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG7544 11-Aug-17 DroID_v2017_08 Drer\mettl16 - Cele\mett-10 Xtro\mettl16 Mmus\Mettl16 Hsap\METTL16 FBgn0034579 mRpL54 mitochondrial ribosomal protein L54 http://flybase.org/reports/FBgn0034579 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000000472 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with SGD:S000000472 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "MRP-L54, CG9353, BcDNA:SD09147, mRpL54" "IPR013870:Ribosomal protein L37, mitochondrial" CG9353 11-Aug-17 DroID_v2017_08 Drer\mrpl54 Scer\MRPL37 Cele\mrpl-54 - Mmus\Mrpl54 Hsap\MRPL54 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0031141 CG1304 - http://flybase.org/reports/FBgn0031141 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP46, CG1304" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG1304 11-Aug-17 DroID_v2017_08 "Drer\LOC558805, Drer\si:ch211-165b19.5, Drer\si:dkey-21e2.16, Drer\si:dkeyp-93a5.3, Drer\si:ch211-165b19.8, Drer\gzmk, Drer\si:dkey-16l2.17, Drer\gzma, Drer\zgc:92313, Drer\zgc:163079, Drer\si:ch211-165b19.9, Drer\ovch1, Drer\cfd, Drer\LOC100004427, Drer\zgc:165423, Drer\si:dkey-21e2.3, Drer\gzm3" - "Cele\try-1, Cele\try-6, Cele\svh-1" - "Mmus\Egfbp2, Mmus\Klk14, Mmus\Klk1b16, Mmus\Klk15, Mmus\Klk1b8, Mmus\Klk9, Mmus\Prss55" "Hsap\KLK9, Hsap\CFD, Hsap\GZMA, Hsap\KLK15, Hsap\TPSD1, Hsap\KLK14" viable FBgn0036436 CG4914 - http://flybase.org/reports/FBgn0036436 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP39, CG4914" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG4914 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-57c15.4, Drer\f7i, Drer\zgc:171592, Drer\si:ch211-165b19.9, Drer\zgc:92745, Drer\zgc:112160, Drer\proca, Drer\si:ch211-165b19.5, Drer\zgc:92511, Drer\f10, Drer\tmprss4a, Drer\f2, Drer\zgc:165423, Drer\ela3l, Drer\tmprss4b, Drer\si:dkey-16l2.17, Drer\ctrl, Drer\ovch1, Drer\gzma, Drer\si:ch211-165b19.8, Drer\zgc:92313, Drer\f9b, Drer\si:dkey-33i11.3, Drer\ctrb1, Drer\ela2l, Drer\tmprss3a, Drer\zgc:163025, Drer\zgc:163079, Drer\zgc:112302, Drer\ela2, Drer\si:dkeyp-93a5.3, Drer\cfd, Drer\f7, Drer\zgc:112285, Drer\gzm3, Drer\zgc:92041, Drer\gzmk, Drer\si:dkey-238d18.3, Drer\LOC100004427, Drer\zgc:112368, Drer\tmprss13a, Drer\f9a, Drer\zgc:154142, Drer\LOC562139" - "Cele\try-6, Cele\svh-1, Cele\try-1" "Xtro\prss29, Xtro\f7, Xtro\f10, Xtro\LOC100135144, Xtro\f9, Xtro\masp1, Xtro\cela2a, Xtro\f2, Xtro\ctrb1, Xtro\cela3a, Xtro\ctrb2, Xtro\proc, Xtro\proz, Xtro\prss56" "Mmus\F10, Mmus\Tmprss11e, Mmus\Proz, Mmus\Tmprss11f, Mmus\Cela2a, Mmus\Cela3a, Mmus\Ctrb1, Mmus\Cela1, Mmus\F2, Mmus\Tmprss11c, Mmus\Tmprss11d, Mmus\Proc, Mmus\Klk15, Mmus\F9, Mmus\Ctrc, Mmus\F7, Mmus\Klk1b4, Mmus\Prss56, Mmus\Cela3b, Mmus\Tmprss11b, Mmus\Ctrl, Mmus\Tmprss11g, Mmus\Klk9, Mmus\C1s1, Mmus\Tmprss11a" "Hsap\PRSS56, Hsap\OVCH1, Hsap\CELA3B, Hsap\F10, Hsap\TMPRSS3, Hsap\F2, Hsap\CELA2B, Hsap\PROZ, Hsap\F7, Hsap\HPN, Hsap\PROC, Hsap\TMPRSS2, Hsap\TMPRSS5, Hsap\CTRB2, Hsap\CTRB1, Hsap\F9, Hsap\C1S, Hsap\KLK15, Hsap\CELA2A, Hsap\CTRC, Hsap\CELA3A, Hsap\CELA1, Hsap\KLK9, Hsap\CTRL" "viable,fertile" FBgn0031309 Tfb4 Transcription factor B4 http://flybase.org/reports/FBgn0031309 protein_coding_gene "DNA-dependent ATPase activity ; GO:0008094 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000302934 DNA-dependent ATPase activity ; GO:0008094 | contributes_to inferred from sequence or structural similarity with HGNC:4657 translation factor activity, RNA binding ; GO:0008135 | inferred from biological aspect of ancestor with PANTHER:PTN000302934 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000302934 damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000302934 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | contributes_to inferred from sequence or structural similarity with HGNC:4657" transcriptional open complex formation at RNA polymerase II promoter ; GO:0001113 | inferred from sequence or structural similarity with SGD:S000006260 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with SGD:S000006260 phosphorylation of RNA polymerase II C-terminal domain ; GO:0070816 | inferred from biological aspect of ancestor with PANTHER:PTN000302934 promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from sequence or structural similarity with SGD:S000006260 response to UV ; GO:0009411 | inferred from sequence or structural similarity with SGD:S000006260 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4657 inferred from sequence or structural similarity with SGD:S000006260 nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity with SGD:S000006260 nucleotide-excision repair ; GO:0006289 | inferred from biological aspect of ancestor with PANTHER:PTN000302934 holo TFIIH complex ; GO:0005675 | inferred from biological aspect of ancestor with PANTHER:PTN000302934 holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:4657 inferred from sequence or structural similarity with SGD:S000006260 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000006260 core TFIIH complex ; GO:0000439 | inferred from sequence or structural similarity with HGNC:4657 inferred from sequence or structural similarity with SGD:S000006260 core TFIIH complex ; GO:0000439 | inferred from biological aspect of ancestor with PANTHER:PTN000302934 "TFB4, CG5041, Tfb4, p34, Dmp34" IPR004600:TFIIH subunit Tfb4/p34 CG5041 11-Aug-17 DroID_v2017_08 Drer\gtf2h3 Scer\TFB4 Cele\ZK1128.4 Xtro\gtf2h3 Mmus\Gtf2h3 Hsap\GTF2H3 "viable,visible,female fertile" mesothoracic tergum DRSC26946 K 0.499302973 -0.97930976 -0.030545737 -0.178333262 1.735072587 0.093298673 FBgn0042696 NfI Nuclear factor I http://flybase.org/reports/FBgn0042696 protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000896695" "DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR000647, InterPro:IPR020604 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000896695 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000896695" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000896695 "CG2380, NFI, NfI" "IPR000647:CTF transcription factor/nuclear factor 1, IPR003619:MAD homology 1, Dwarfin-type, IPR019548:CTF transcription factor/nuclear factor 1, N-terminal, IPR020604:CTF transcription factor/nuclear factor 1, DNA-binding domain" CG2380 11-Aug-17 DroID_v2017_08 "Drer\nfic, Drer\nfia, Drer\nfixb" - Cele\nfi-1 "Xtro\nfix, Xtro\nfib, Xtro\nfic, Xtro\nfia" "Mmus\Nfia, Mmus\Nfib, Mmus\Nfic, Mmus\Nfix" "Hsap\NFIX, Hsap\NFIA, Hsap\NFIB, Hsap\NFIC" viable FBgn0053886 His2B:CG33886 His2B:CG33886 http://flybase.org/reports/FBgn0053886 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33886, His2B:CG33886" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33886 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-23a13.16, Drer\si:dkey-108k21.27, Drer\zgc:194989, Drer\si:ch1073-159d7.13, Drer\si:ch211-113a14.28, Drer\LOC100334869, Drer\si:ch1073-153i20.3, Drer\hist1h2ba, Drer\si:dkey-23a13.5, Drer\si:dkey-108k21.11, Drer\si:ch73-368j24.8, Drer\si:ch211-113a14.11, Drer\si:ch211-113a14.29, Drer\zgc:92591, Drer\si:ch73-36p18.3, Drer\zgc:173587, Drer\si:dkey-23a13.1, Drer\zgc:173585, Drer\si:ch1073-159d7.5, Drer\zgc:114046, Drer\LOC100329290, Drer\si:dkey-261m9.19, Drer\LOC100334559, Drer\ano9a, Drer\hist2h2l, Drer\LOC100329560, Drer\si:dkey-261m9.6" "Scer\HTB2, Scer\HTB1" "Cele\his-34, Cele\his-41, Cele\his-39, Cele\his-20, Cele\his-58, Cele\his-48, Cele\his-11, Cele\his-29, Cele\his-4, Cele\his-8, Cele\his-22, Cele\his-62, Cele\his-52, Cele\his-54, Cele\his-44, Cele\his-15, Cele\his-66" "Xtro\LOC101730940, Xtro\LOC100496436, Xtro\LOC100492632, Xtro\LOC101731067, Xtro\LOC101733489, Xtro\LOC100497915, Xtro\LOC101733171, Xtro\LOC101733828, Xtro\LOC100496445, Xtro\LOC100485294, Xtro\LOC101734862, Xtro\LOC100485134, Xtro\LOC100487485, Xtro\LOC100495578, Xtro\LOC100486870, Xtro\hist2h2be, Xtro\LOC101735164, Xtro\LOC100498647, Xtro\LOC100498553, Xtro\hist1h2bm, Xtro\LOC100497082, Xtro\LOC100486150, Xtro\hist1h2bj, Xtro\LOC100495415, Xtro\LOC100496181, Xtro\LOC101731959, Xtro\LOC101734494, Xtro\LOC100495396, Xtro\hist1h2bk, Xtro\LOC101735218, Xtro\LOC100495041, Xtro\LOC100498072, Xtro\LOC101731852, Xtro\LOC100498329" "Mmus\Hist1h2bq, Mmus\Hist1h2bn, Mmus\Hist1h2bk, Mmus\Hist1h2bg, Mmus\Hist1h2ba, Mmus\Hist1h2bj, Mmus\Hist1h2bh, Mmus\Hist1h2bl, Mmus\Hist1h2bm, Mmus\1700024P04Rik, Mmus\Hist2h2bb, Mmus\Hist1h2bp, Mmus\H2bfm, Mmus\Hist3h2ba, Mmus\Hist1h2bb, Mmus\Hist1h2bc, Mmus\Hist1h2bf, Mmus\Hist1h2be, Mmus\Hist1h2br, Mmus\Hist2h2be" "Hsap\HIST2H2BE, Hsap\HIST1H2BE, Hsap\HIST3H2BB, Hsap\H2BFWT, Hsap\HIST1H2BI, Hsap\HIST2H2BF, Hsap\HIST1H2BK, Hsap\HIST1H2BC, Hsap\HIST1H2BL, Hsap\H2BFM, Hsap\HIST1H2BF, Hsap\HIST1H2BO, Hsap\HIST1H2BM, Hsap\HIST1H2BA, Hsap\HIST1H2BG, Hsap\HIST1H2BN, Hsap\HIST1H2BH, Hsap\HIST1H2BD, Hsap\HIST1H2BB, Hsap\HIST1H2BJ" FBgn0038772 mdlc midlife crisis http://flybase.org/reports/FBgn0038772 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model "neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from biological aspect of ancestor with PANTHER:PTN000309255 neuron differentiation ; GO:0030182 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004315 regulation of RNA splicing ; GO:0043484 | inferred from direct assay snoRNA splicing ; GO:0034247 | inferred from biological aspect of ancestor with PANTHER:PTN000309255" U2-type spliceosomal complex ; GO:0005684 | inferred from biological aspect of ancestor with PANTHER:PTN000309255 U2-type spliceosomal complex ; GO:0005684 | inferred from sequence or structural similarity with SGD:S000004315 nucleus ; GO:0005634 | inferred from direct assay "CG4973, mdlc" "IPR000571:Zinc finger, CCCH-type, IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4973 11-Aug-17 DroID_v2017_08 "Drer\rnf113a, Drer\naa50" "Scer\CWC24, Scer\NAT5" "Cele\rnf-113, Cele\F40F4.7" "Xtro\naa50, Xtro\rnf113a" "Mmus\Naa50, Mmus\Rnf113a1, Mmus\Rnf113a2" "Hsap\RNF113A, Hsap\RNF113B, Hsap\NAA50" "lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage,recessive,mitotic cell cycle defective,somatic clone,viable,lethal - all die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,neuroblast,somatic clone" FBgn0266666 Sem1 Suppressor of exocyst mutations 1 http://flybase.org/reports/FBgn0266666 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mRNA export from nucleus ; GO:0006406 | inferred from electronic annotation with InterPro:IPR007834 proteasome assembly ; GO:0043248 | inferred from electronic annotation with InterPro:IPR007834 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000007235 neurogenesis ; GO:0022008 | inferred from mutant phenotype "proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from electronic annotation with InterPro:IPR007834 proteasome complex ; GO:0000502 | inferred from sequence or structural similarity with SGD:S000007235 proteasome complex ; GO:0000502 | inferred from sequence or structural similarity with UniProtKB:P60896" "sem1, Sem1p, Sem1, CG13779, dss1, BcDNA:RH34416, dmdss1" IPR007834:DSS1/SEM1 CG13779 11-Aug-17 DroID_v2017_08 Drer\shfm1 Scer\SEM1 Cele\dss-1 Xtro\shfm1 Mmus\Shfm1 Hsap\SHFM1 DRSC02282 I 2.143935236 -2.093601015 -0.787468133 -0.69995419 1.191399367 0.238840768 FBgn0024288 Sox100B Sox100B http://flybase.org/reports/FBgn0024288 "FBgn0039814, FBgn0039815, FBgn0040626" protein_coding_gene - male gonad development ; GO:0008584 | inferred from expression pattern male gonad development ; GO:0008584 | inferred from mutant phenotype - "CT6009, Sox9, SOXE, SOX100B, CG12098, SoxB, CG18674, CG15552, Sox100B, Sox100" "IPR009071:High mobility group box domain, IPR022151:Sox developmental protein N-terminal" CG15552 11-Aug-17 DroID_v2017_08 "Drer\sox9a, Drer\sox9b, Drer\sox8b, Drer\sox10, Drer\sox8a" Scer\ROX1 - "Xtro\sox9, Xtro\sox8, Xtro\sox10" "Mmus\Sox9, Mmus\Sox10, Mmus\Sox8" "Hsap\SOX10, Hsap\SOX8, Hsap\SOX9" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC15090 E -1.231355052 -0.753709228 2.263631832 -0.251926003 0.290914526 0.602503394 FBgn0085425 CG34396 - http://flybase.org/reports/FBgn0085425 protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" "CG34396, CG15654, anon-WO0109301.1, anon-WO0109301.17, anon-WO0109301.16, CG15655" "IPR013099:Potassium channel domain, IPR003280:Two pore domain potassium channel" CG34396 11-Aug-17 DroID_v2017_08 "Drer\kcnk5b, Drer\kcnk18, Drer\kcnk1b, Drer\kcnk1a, Drer\kcnk6, Drer\kcnk7, Drer\kcnk10b, Drer\kcnk2a, Drer\kcnk10a, Drer\kcnk5a" Scer\TOK1 "Cele\twk-32, Cele\twk-36, Cele\twk-47, Cele\unc-58, Cele\egl-23, Cele\twk-34, Cele\twk-44, Cele\twk-45, Cele\twk-48, Cele\twk-21, Cele\twk-4, Cele\twk-17, Cele\twk-9, Cele\twk-22, Cele\twk-12, Cele\twk-10, Cele\twk-26, Cele\twk-6, Cele\twk-30, Cele\twk-43, Cele\twk-3, Cele\twk-8, Cele\twk-23, Cele\twk-31, Cele\twk-24, Cele\twk-18, Cele\twk-40, Cele\twk-11, Cele\twk-2, Cele\twk-29, Cele\twk-35, Cele\twk-1, Cele\twk-42, Cele\C27F2.6, Cele\B0310.1, Cele\twk-28, Cele\twk-13, Cele\twk-33, Cele\twk-16, Cele\twk-7, Cele\twk-25, Cele\twk-37" "Xtro\kcnk2, Xtro\kcnk7, Xtro\LOC100486031, Xtro\kcnk1, Xtro\kcnk6, Xtro\kcnk16, Xtro\kcnk5, Xtro\kcnk4, Xtro\kcnk10, Xtro\kcnk18" "Mmus\Kcnk18, Mmus\Kcnk2, Mmus\Kcnk5, Mmus\Kcnk4, Mmus\Kcnk1, Mmus\Kcnk10, Mmus\Kcnk6, Mmus\Kcnk16, Mmus\Kcnk7" "Hsap\KCNK4, Hsap\KCNK18, Hsap\KCNK1, Hsap\KCNK17, Hsap\KCNK10, Hsap\KCNK5, Hsap\KCNK6, Hsap\KCNK7, Hsap\KCNK16, Hsap\KCNK2" "lethal,viable,visible" trichogen cell DRSC04245 E -0.524740195 -1.016988458 -1.135160504 -2.498587642 0.746714656 0.340389751 FBgn0029993 CG1571 - http://flybase.org/reports/FBgn0029993 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:Q9GZS0 outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q9GZS0 CG1571 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain" CG1571 11-Aug-17 DroID_v2017_08 "Drer\LOC103908626, Drer\dnai2a, Drer\dync1i1, Drer\dnai2b, Drer\dnai1.1, Drer\dync1i2b" - Cele\prp-17 "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Dnaic2, Mmus\Wdr63, Mmus\Dync1i1, Mmus\Dync1i2" "Hsap\DYNC1I1, Hsap\DNAI2, Hsap\WDR60, Hsap\DYNC1I2" DRSC18068 I 2.272284446 0.413357801 0.186415917 0.369183187 0.053981636 0.553018447 FBgn0250844 CG4218 - http://flybase.org/reports/FBgn0250844 protein_coding_gene - - - "BG:DS04641.8, CG4218, anon-SAGE:Wang-118, anon-SAGE:Wang-133" - CG4218 11-Aug-17 DroID_v2017_08 - - - - - - DRSC01939 K -0.563211813 -0.284712191 0.30512578 0.276890398 1.99757707 1.939138462 FBgn0003279 RpL4 Ribosomal protein L4 http://flybase.org/reports/FBgn0003279 FBgn0046357 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002136, InterPro:IPR023574 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement" ribosome ; GO:0005840 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "RpL1, CG5502, rpL1, anon-WO0172774.76, RpL4, Rp L4, L4, chr3R:23749174..23749334" "IPR025755:60S ribosomal protein L4, C-terminal domain, IPR002136:Ribosomal protein L4/L1e, IPR013000:Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site, IPR023574:Ribosomal protein L4 domain" CG5502 11-Aug-17 DroID_v2017_08 Drer\rpl4 "Scer\RPL4B, Scer\RPL4A" Cele\rpl-4 Xtro\rpl4 Mmus\Rpl4 Hsap\RPL4 DRSC16833 IEK 1.082745463 -1.544393439 -1.388858262 -5.047682376 1.106202201 3.04864626 FBgn0031420 Atxn7 Ataxin 7 http://flybase.org/reports/FBgn0031420 protein_coding_gene molecular_function ; GO:0003674 | no biological data available SAGA complex assembly ; GO:0036285 | inferred from mutant phenotype positive regulation of histone H2B ubiquitination ; GO:2001168 | inferred from mutant phenotype SAGA complex ; GO:0000124 | inferred from direct assay SAGA-type complex ; GO:0070461 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG9866, Atxn7" - CG9866 11-Aug-17 DroID_v2017_08 - - - - - - "majority die during prepupal stage,short lived,locomotor behavior defective,neuroanatomy defective,lethal,progressive" "adult brain,retina,eye,progressive" DRSC23138 K -0.613893778 0.942248093 0.233219194 1.113444305 0.729391868 1.939400138 FBgn0052016 4E-T eIF4E-Transporter http://flybase.org/reports/FBgn0052016 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG11232, CG11097, CG32016, 4E-T, Dm4E-T" IPR018862:Eukaryotic translation initiation factor 4E binding protein CG32016 11-Aug-17 DroID_v2017_08 Drer\eif4enif1 - Cele\ifet-1 Xtro\eif4enif1 Mmus\Eif4enif1 Hsap\EIF4ENIF1 "viable,fertile" DRSC17201 E -0.811226145 -0.904777303 -1.814283801 -0.850576363 0.35606129 0.090801119 FBgn0038387 blp black pearl http://flybase.org/reports/FBgn0038387 protein_coding_gene - embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000273250 neurogenesis ; GO:0022008 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000273250 "l(3)01618, CG5268, BcDNA:RE11908, blp, Blp" "IPR005341:Mitochondrial import inner membrane translocase subunit Tim16, IPR001623:DnaJ domain" CG5268 11-Aug-17 DroID_v2017_08 Drer\pam16 Scer\PAM16 Cele\F45G2.8 "Xtro\pam16, Xtro\coro7" Mmus\Pam16 "Hsap\PAM16, Hsap\CORO7-PAM16" "lethal,recessive,partially lethal - majority die,melanotic mass phenotype,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,body color defective,some die during pupal stage" "melanotic mass,embryonic/first instar larval cuticle,segment,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC28887 K 0.572622302 0.721312543 -0.113439219 -0.028401821 0.76541783 2.51168194 FBgn0032596 Prosbeta4 Proteasome beta4 subunit http://flybase.org/reports/FBgn0032596 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome core complex ; GO:0005839 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay "GC17331, PSMB2, 17331, Prosbeta4, Psmb2, CG17331, Beta-4, beta4, beta-4" "IPR001353:Proteasome, subunit alpha/beta, IPR023333:Proteasome B-type subunit, IPR016050:Proteasome beta-type subunit, conserved site, IPR029055:Nucleophile aminohydrolases, N-terminal" CG17331 11-Aug-17 DroID_v2017_08 Drer\psmb2 Scer\PRE1 Cele\pbs-4 Xtro\psmb2 Mmus\Psmb2 Hsap\PSMB2 "viable,fertile,lethal" ventral furrow DRSC02603 IE -0.712565525 -2.243417621 -1.816612613 -3.584452755 1.472082813 -0.378061121 FBgn0033321 CG8738 - http://flybase.org/reports/FBgn0033321 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "CG8738, SPH121, c-SPH121" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG8738 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Klk1, Mmus\Klk1b26, Mmus\Klk1b11, Mmus\Klk1b8, Mmus\Klk1b22, Mmus\F11, Mmus\Klk1b1, Mmus\Klk1b24, Mmus\Klk1b4, Mmus\Klk11, Mmus\Klk1b21, Mmus\Klkb1, Mmus\Klk1b3, Mmus\Egfbp2, Mmus\Klk1b9, Mmus\Klk1b5, Mmus\Klk1b16, Mmus\Klk1b27" "Hsap\F11, Hsap\KLKB1, Hsap\KLK2, Hsap\KLK1, Hsap\KLK11, Hsap\KLK3" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0263006 SERCA Sarco/endoplasmic reticulum Ca(2+)-ATPase http://flybase.org/reports/FBgn0263006 protein_coding_gene calcium-transporting ATPase activity ; GO:0005388 | inferred from electronic annotation with InterPro:IPR005782 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR030327 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250 protein binding ; GO:0005515 | inferred from physical interaction with egg calcium-transporting ATPase activity ; GO:0005388 | inferred from sequence or structural similarity "regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype stem cell differentiation ; GO:0048863 | inferred from mutant phenotype positive regulation of calcium-transporting ATPase activity ; GO:1901896 | inferred from genetic interaction with RyR intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from genetic interaction with Itp-r83A ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype heart contraction ; GO:0060047 | inferred from mutant phenotype positive regulation of lipid storage ; GO:0010884 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype lipid biosynthetic process ; GO:0008610 | inferred from mutant phenotype regulation of sequestering of calcium ion ; GO:0051282 | inferred from mutant phenotype fatty acid beta-oxidation ; GO:0006635 | inferred from mutant phenotype cellular calcium ion homeostasis ; GO:0006874 | inferred from mutant phenotype stabilization of membrane potential ; GO:0030322 | inferred from genetic interaction with Gαq, Plc21C, Itp-r83A" "sarcoplasmic reticulum membrane ; GO:0033017 | inferred from electronic annotation with InterPro:IPR030327 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR005782 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q93084 endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay sarcoplasmic reticulum ; GO:0016529 | inferred from sequence or structural similarity with UniProtKB:Q93084 sarcoplasmic reticulum ; GO:0016529 |" "SERCA, dSERCA, Kum, CaP60A, Ca-P60A, CG3725, Ca-P60, Ca-ATPase, l(2)k09025, CA-P60A, Ca[2+]ATPase, l(2)k08308ab, Ca-p, SERCA2, Serca2a, l(2)SH0211, dserca, kum, ATC1_DROME, A4UZU0_DROME, Serca, 17136664, serca" "IPR030327:Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, IPR023299:P-type ATPase, cytoplasmic domain N, IPR023298:P-type ATPase, transmembrane domain, IPR023214:HAD-like domain, IPR001757:P-type ATPase, IPR004014:Cation-transporting P-type ATPase, N-terminal, IPR005782:P-type ATPase, subfamily IIA, SERCA-type, IPR006068:Cation-transporting P-type ATPase, C-terminal, IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site" CG3725 11-Aug-17 DroID_v2017_08 "Drer\atp2a2a, Drer\atp2c1, Drer\si:dkey-28b4.8, Drer\atp2a1, Drer\atp2a2b, Drer\atp2a3, Drer\atp2a1l" "Scer\PMR1, Scer\ENA2, Scer\ENA1, Scer\ENA5" "Cele\pmr-1, Cele\sca-1" "Xtro\atp2a1, Xtro\atp2a2, Xtro\atp2c2, Xtro\atp2c1" "Mmus\Atp2a1, Mmus\Atp2a3, Mmus\Atp2c2, Mmus\Atp2c1, Mmus\Atp2a2" "Hsap\ATP2A2, Hsap\ATP2A3, Hsap\ATP2C1, Hsap\ATP2A1, Hsap\ATP2C2" " adult stage , adult stage | female " " ganglion cell &&of ocellus

, oocyte

, optic lobe

, skeletal muscle of mesothorax

, pharyngeal muscle

, cibarial muscle

, tubular muscle

, salivary pump muscle 13

, ocellus | vicinity of

, adult central nervous system

" FBgn0053840 His1:CG33840 His1:CG33840 http://flybase.org/reports/FBgn0053840 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33840, His1:CG33840" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33840 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-159d7.7, Drer\zgc:110425, Drer\si:dkey-261m9.12, Drer\si:ch211-113a14.24, Drer\h1f0, Drer\zgc:110216, Drer\h1m, Drer\si:ch73-36p18.1, Drer\si:dkey-108k21.21, Drer\si:dkey-108k21.10, Drer\h1fx, Drer\zgc:163061, Drer\zgc:153405, Drer\histh1l, Drer\si:dkey-108k21.14" Scer\HHO1 "Cele\hil-1, Cele\his-24, Cele\hil-2, Cele\hil-4, Cele\hil-3, Cele\hil-5, Cele\hil-6" - "Mmus\Hist1h1c, Mmus\H1foo, Mmus\Hist1h1a, Mmus\Hist1h1d, Mmus\H1fnt, Mmus\Hist1h1b, Mmus\Hist1h1t, Mmus\H1fx, Mmus\Hils1, Mmus\Hist1h1e" "Hsap\HIST1H1B, Hsap\HIST1H1A, Hsap\HIST1H1T, Hsap\HIST1H1E, Hsap\HIST1H1D, Hsap\H1F0, Hsap\H1FOO, Hsap\H1FX, Hsap\H1FNT, Hsap\HIST1H1C" FBgn0020622 Pi3K21B Pi3K21B http://flybase.org/reports/FBgn0020622 "FBgn0020262, FBgn0024844" protein_coding_gene phosphatidylinositol 3-kinase regulator activity ; GO:0035014 | inferred from sequence or structural similarity with MGI:MGI:109277 kinase binding ; GO:0019900 | inferred from physical interaction with Pi3K92E phosphatidylinositol 3-kinase regulator activity ; GO:0035014 | inferred from sequence or structural similarity with protein_id:BAA10927.1 inferred from sequence or structural similarity with protein_id:BAA18933.1 insulin receptor substrate binding ; GO:0043560 | inferred from sequence or structural similarity with UniProtKB:P26450 phosphatidylinositol 3-kinase regulator activity ; GO:0035014 | inferred from sequence or structural similarity with HGNC:8979 1-phosphatidylinositol-3-kinase regulator activity ; GO:0046935 | inferred from biological aspect of ancestor with PANTHER:PTN000806614 positive regulation of growth ; GO:0045927 | traceable author statement phosphatidylinositol phosphorylation ; GO:0046854 | inferred from direct assay positive regulation of cell size ; GO:0045793 | traceable author statement regulation of cell size ; GO:0008361 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | traceable author statement regulation of phosphatidylinositol 3-kinase activity ; GO:0043551 | inferred from biological aspect of ancestor with PANTHER:PTN000016388 regulation of organ growth ; GO:0046620 | non-traceable author statement lipid phosphorylation ; GO:0046834 | inferred from direct assay "phosphatidylinositol 3-kinase complex ; GO:0005942 | inferred from biological aspect of ancestor with PANTHER:PTN000806614 phosphatidylinositol 3-kinase complex, class IA ; GO:0005943 | non-traceable author statement phosphatidylinositol 3-kinase complex, class IA ; GO:0005943 | inferred from physical interaction with UniProtKB:P91634" "p60, PI3K, dPI3K, Pi3Kp60, CG2699, PI(3)K, droPIK57, Pi3K21B, PI3K21B, dP60, PI[[3]]K, Dp60, PI3K-p60, Pi3K21B|p60, Pi3k21B, dp110" "IPR001720:PI3K p85 subunit, IPR000980:SH2 domain, IPR032498:PI3K p85 subunit, inter-SH2 domain" CG2699 11-Aug-17 DroID_v2017_08 "Drer\pik3r3b, Drer\ccdc39, Drer\pik3r2, Drer\plcg2, Drer\pik3r1, Drer\plcg1, Drer\pik3r3a" Scer\LSB1 "Cele\vav-1, Cele\F39B2.5, Cele\aap-1" "Xtro\pik3r1, Xtro\pik3r2, Xtro\pik3r3" "Mmus\Pik3r3, Mmus\Pik3r2, Mmus\Pik3r1" "Hsap\PIK3R1, Hsap\FER, Hsap\PIK3R3, Hsap\PIK3R2" " embryonic stage | stage 5-10 , embryonic stage | stage 16 , embryonic stage | early , adult stage | female , embryonic stage -- adult stage , adult stage | male , adult stage " " pole cell

, prothoracic segment | restricted

, embryonic/larval midgut

, adult head

, mesothoracic segment | restricted

" larval stage&&pupal stage&&adult stage "viable,fertile,wild-type,small body,somatic clone,decreased cell size" "egg chamber,germline clone,imaginal disc & cell,embryonic/larval salivary gland,somatic clone,cell cycle | somatic clone,embryonic/larval fat body,embryonic/larval ganglionic branch,mushroom body neuroblast,embryonic/larval neuroblast" FBgn0030332 CG9360 - http://flybase.org/reports/FBgn0030332 protein_coding_gene - - - "CG9360, FOHSDR" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG9360 11-Aug-17 DroID_v2017_08 "Drer\zgc:92630, Drer\rdh8a, Drer\zgc:153724, Drer\rdh8b, Drer\dhrs11a, Drer\dhrs11b" Scer\YMR226C "Cele\R05D8.7, Cele\F28H7.2, Cele\H04M03.3" "Xtro\dhrs11, Xtro\rdh7, Xtro\rdh8" "Mmus\Rdh1, Mmus\Dhrs11, Mmus\Rdh8" "Hsap\RDH16, Hsap\RDH8, Hsap\DHRS11" viable FBgn0040060 yip7 yippee interacting protein 7 http://flybase.org/reports/FBgn0040060 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP116, SPH116, MAC, mac, CG6457, yip7" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG6457 11-Aug-17 DroID_v2017_08 "Drer\zgc:92041, Drer\zgc:92745, Drer\zgc:112285, Drer\ela3l, Drer\zgc:112302, Drer\zgc:112368" - - - "Mmus\Ctrc, Mmus\Cela2a, Mmus\Cela3a, Mmus\Ctrl, Mmus\Cela3b, Mmus\Ctrb1, Mmus\Cela1" Hsap\KLK3 viable FBgn0034035 CG8207 - http://flybase.org/reports/FBgn0034035 protein_coding_gene nucleotidyltransferase activity ; GO:0016779 | inferred from electronic annotation with InterPro:IPR005835 biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR005835 - CG8207 "IPR005835:Nucleotidyl transferase domain, IPR029044:Nucleotide-diphospho-sugar transferases, IPR001451:Hexapeptide repeat" CG8207 11-Aug-17 DroID_v2017_08 "Drer\gmppaa, Drer\gmppab" Scer\PSA1 Cele\Y47D9A.1 Xtro\gmppa Mmus\Gmppa "Hsap\GMPPB, Hsap\GMPPA" viable FBgn0030575 CG5321 - http://flybase.org/reports/FBgn0030575 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003819 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003819 - "anon-EST:Posey66, CG5321" "IPR003819:TauD/TfdA-like domain, IPR010376:Domain of unknown function DUF971" CG5321 11-Aug-17 DroID_v2017_08 "Drer\tmlhe, Drer\bbox1" Scer\AIM17 "Cele\gbh-1, Cele\gbh-2" "Xtro\tmlhe, Xtro\bbox1" "Mmus\Tmlhe, Mmus\Bbox1" "Hsap\TMLHE, Hsap\BBOX1" viable FBgn0020506 Amyrel Amyrel http://flybase.org/reports/FBgn0020506 - protein_coding_gene "cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR006046, InterPro:IPR006047, InterPro:IPR006048, InterPro:IPR006589 catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006046, InterPro:IPR006047, InterPro:IPR006048, InterPro:IPR006589, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006046, InterPro:IPR006047, InterPro:IPR006048, InterPro:IPR006589, InterPro:IPR013781" - "CG8221, Amyrel, AmyRel, amyrel" "IPR006046:Alpha amylase, IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR006048:Alpha-amylase/branching enzyme, C-terminal all beta, IPR017853:Glycoside hydrolase superfamily, IPR031319:Alpha-amylase, C-terminal domain" CG8221 11-Aug-17 DroID_v2017_08 "Drer\zgc:66313, Drer\zgc:92137, Drer\amy2a" "Scer\MAL32, Scer\MAL12" Cele\C50B6.7 "Xtro\amy2a, Xtro\amy2b" "Mmus\Amy2a3, Mmus\Amy1, Mmus\Amy2a4, Mmus\Amy2a1, Mmus\Amy2a5, Mmus\Amy2a2" "Hsap\AMY1C, Hsap\AMY1B, Hsap\AMY1A, Hsap\AMY2A, Hsap\AMY2B, Hsap\SLC3A1" " larval stage | third instar , larval stage | second instar " FBgn0053888 His2B:CG33888 His2B:CG33888 http://flybase.org/reports/FBgn0053888 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33888, His2B:CG33888" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33888 11-Aug-17 DroID_v2017_08 "Drer\ano9a, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.16, Drer\si:ch211-113a14.28, Drer\si:dkey-23a13.1, Drer\LOC100334869, Drer\si:dkey-108k21.11, Drer\si:ch1073-153i20.3, Drer\hist2h2l, Drer\zgc:173587, Drer\si:ch1073-159d7.5, Drer\si:dkey-261m9.19, Drer\zgc:194989, Drer\hist1h2ba, Drer\si:ch73-36p18.3, Drer\zgc:114046, Drer\LOC100329560, Drer\si:ch1073-159d7.13, Drer\zgc:92591, Drer\LOC100329290, Drer\si:dkey-261m9.6, Drer\si:dkey-108k21.27, Drer\si:dkey-23a13.5, Drer\si:ch211-113a14.29, Drer\zgc:173585, Drer\si:ch73-368j24.8, Drer\LOC100334559" "Scer\HTB2, Scer\HTB1" "Cele\his-34, Cele\his-15, Cele\his-62, Cele\his-39, Cele\his-58, Cele\his-52, Cele\his-66, Cele\his-48, Cele\his-29, Cele\his-22, Cele\his-41, Cele\his-54, Cele\his-4, Cele\his-11, Cele\his-8, Cele\his-44, Cele\his-20" "Xtro\LOC100485134, Xtro\LOC101731959, Xtro\LOC100495041, Xtro\LOC100496181, Xtro\LOC100487485, Xtro\hist2h2be, Xtro\LOC100495415, Xtro\LOC101735164, Xtro\hist1h2bk, Xtro\LOC101734862, Xtro\LOC100485294, Xtro\LOC100498329, Xtro\LOC100486870, Xtro\LOC100496445, Xtro\LOC100496436, Xtro\LOC101735218, Xtro\LOC100497915, Xtro\hist1h2bj, Xtro\LOC100498553, Xtro\LOC100498072, Xtro\LOC101730940, Xtro\LOC101733489, Xtro\LOC100497082, Xtro\LOC101731852, Xtro\LOC101733171, Xtro\LOC100492632, Xtro\LOC101734494, Xtro\LOC100498647, Xtro\LOC101733828, Xtro\LOC100486150, Xtro\LOC100495396, Xtro\LOC100495578, Xtro\LOC101731067, Xtro\hist1h2bm" "Mmus\Hist3h2ba, Mmus\Hist1h2be, Mmus\Hist1h2bj, Mmus\Hist1h2bl, Mmus\Hist1h2bh, Mmus\Hist1h2bq, Mmus\Hist2h2be, Mmus\Hist1h2bp, Mmus\Hist1h2ba, Mmus\Hist1h2bm, Mmus\Hist1h2bb, Mmus\Hist1h2br, Mmus\Hist2h2bb, Mmus\Hist1h2bk, Mmus\Hist1h2bn, Mmus\H2bfm, Mmus\Hist1h2bf, Mmus\Hist1h2bg, Mmus\Hist1h2bc, Mmus\1700024P04Rik" "Hsap\H2BFWT, Hsap\HIST3H2BB, Hsap\HIST1H2BD, Hsap\HIST1H2BC, Hsap\HIST1H2BG, Hsap\HIST1H2BA, Hsap\HIST1H2BH, Hsap\HIST1H2BO, Hsap\HIST2H2BF, Hsap\HIST2H2BE, Hsap\HIST1H2BI, Hsap\HIST1H2BN, Hsap\HIST1H2BJ, Hsap\HIST1H2BM, Hsap\H2BFM, Hsap\HIST1H2BE, Hsap\HIST1H2BF, Hsap\HIST1H2BK, Hsap\HIST1H2BB, Hsap\HIST1H2BL" FBgn0037481 MAGE MAGE http://flybase.org/reports/FBgn0037481 protein_coding_gene SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000002696 negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype response to caffeine ; GO:0031000 | inferred from mutant phenotype inferred from genetic interaction with spn-A inferred from genetic interaction with mei-41 inferred from genetic interaction with tefu inferred from genetic interaction with nbs negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000002696 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000002696 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002696 "MAGE, CG10059, DMAGE, Nse3, sst, Mage" IPR002190:MAGE homology domain CG10059 11-Aug-17 DroID_v2017_08 Drer\ndnl2 "Scer\NSE3, Scer\CHS5" "Cele\fbxc-28, Cele\mage-1" Xtro\nsmce3 "Mmus\Gm14781, Mmus\1700020D05Rik, Mmus\Gm5072, Mmus\4930550L24Rik, Mmus\3830417A13Rik, Mmus\Magea8, Mmus\Magea3, Mmus\Magea5, Mmus\Mageh1, Mmus\Mageb2, Mmus\Mageb16, Mmus\Magea6, Mmus\Mageb18, Mmus\Magea4, Mmus\Ndnl2, Mmus\Maged1, Mmus\Mageb3, Mmus\Mageb1, Mmus\Magel2, Mmus\Magea1, Mmus\Ndn, Mmus\1700080O16Rik, Mmus\Magee2, Mmus\Mageb4, Mmus\Gm44, Mmus\Mageb5, Mmus\Magea2, Mmus\Magea10, Mmus\4933402E13Rik, Mmus\Tro, Mmus\Magee1, Mmus\Maged2" "Hsap\MAGEB3, Hsap\MAGED1, Hsap\MAGEE2, Hsap\MAGEA9, Hsap\MAGED4, Hsap\MAGEC2, Hsap\MAGED2, Hsap\MAGEB10, Hsap\MAGEA11, Hsap\NDN, Hsap\MAGEC3, Hsap\MAGEA3, Hsap\MAGEA10, Hsap\MAGEC1, Hsap\MAGEF1, Hsap\MAGEA9B, Hsap\MAGEA8, Hsap\MAGEA2B, Hsap\NSMCE3, Hsap\MAGEH1, Hsap\MAGEB17, Hsap\MAGEA2, Hsap\MAGEB18, Hsap\MAGEL2, Hsap\MAGEB4, Hsap\MAGED4B, Hsap\MAGEA12, Hsap\MAGEE1, Hsap\MAGEB5, Hsap\MAGEB6, Hsap\TRO, Hsap\MAGEA4, Hsap\MAGEA1, Hsap\MAGEB16, Hsap\MAGEA6, Hsap\MAGEB2, Hsap\MAGEB1, Hsap\MAGEA5" "visible,somatic clone,conditional,chemical sensitive,increased cell death,lethal,radiation sensitive,partially lethal,viable,recessive,increased cell number,neuroanatomy defective" "eye,somatic clone,conditional,eye disc,photoreceptor cell,adult brain,neuron,supernumerary,adult mushroom body" FBgn0032651 Oli Olig family http://flybase.org/reports/FBgn0032651 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with cato motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype" - "Doli, CG5545, Oli, bHLHb23, Olig, oli" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG5545 11-Aug-17 DroID_v2017_08 "Drer\olig4, Drer\olig1, Drer\olig2, Drer\bhlhe22, Drer\si:ch211-196c10.13, Drer\bhlhe23" - "Cele\hlh-16, Cele\hlh-32, Cele\hlh-17, Cele\hlh-31" "Xtro\olig4, Xtro\olig3, Xtro\olig2, Xtro\bhlhe22" "Mmus\Olig3, Mmus\Bhlhe22, Mmus\Twist1, Mmus\Olig1, Mmus\Bhlhe23, Mmus\Olig2" "Hsap\OLIG3, Hsap\OLIG1, Hsap\OLIG2, Hsap\BHLHE23, Hsap\BHLHE22" "neuroanatomy defective,lethal,some die during embryonic stage,locomotor behavior defective,flightless,viable" "intersegmental nerve branch ISNb of A1-7 | embryonic stage,intersegmental nerve branch ISNb of A1-7,transverse nerve,abdominal intersegmental bidendritic neuron isbp" FBgn0052473 CG32473 - http://flybase.org/reports/FBgn0052473 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 angiotensin maturation ; GO:0002003 | inferred from electronic annotation with InterPro:IPR033508 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "GM08240p, CG8775, CG11688, CG32473" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type, IPR033508:Aminopeptidase A" CG32473 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-198g19.1, Drer\anpepa, Drer\enpep, Drer\erap1b, Drer\si:ch211-106j24.1, Drer\anpepb, Drer\erap1a, Drer\npepps, Drer\si:ch211-276a23.5, Drer\erap2, Drer\lnpep, Drer\si:ch211-149p5.1" "Scer\AAP1, Scer\APE2, Scer\TMA108" "Cele\R03G8.4, Cele\R03G8.6, Cele\Y42A5A.1, Cele\Y53F4B.20, Cele\T07F10.1, Cele\AC3.5, Cele\VB0395L.1, Cele\Y67D8C.9, Cele\pam-1, Cele\F49B2.6, Cele\T16G12.1, Cele\T12E12.6, Cele\mnp-1" "Xtro\anpep, Xtro\npepps, Xtro\erap1, Xtro\enpep, Xtro\lnpep, Xtro\lvrn" "Mmus\Lnpep, Mmus\Lvrn, Mmus\Anpep, Mmus\Trhde, Mmus\Erap1, Mmus\Npepps, Mmus\Enpep" "Hsap\ENPEP, Hsap\ERAP2, Hsap\LNPEP, Hsap\NPEPPS, Hsap\LVRN, Hsap\ERAP1, Hsap\ANPEP, Hsap\TRHDE" viable FBgn0266465 GckIII Germinal centre kinase III http://flybase.org/reports/FBgn0266465 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with HGNC:11404" "septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of cell differentiation ; GO:0045595 | inferred from biological aspect of ancestor with PANTHER:PTN000685542 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:11404 apoptotic process ; GO:0006915 | inferred from biological aspect of ancestor with PANTHER:PTN000685542 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with HGNC:11404 "STLK3, GCKIII, wheezy, GckIII, CG5169, dGCKIII, Gck III" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG5169 11-Aug-17 DroID_v2017_08 "Drer\stk24b, Drer\stk24a, Drer\stk25a, Drer\stk25b, Drer\stk26, Drer\stk3, Drer\map3k8" "Scer\KIC1, Scer\SPS1" "Cele\mpk-2, Cele\gck-1, Cele\C03B1.5" "Xtro\stk4, Xtro\stk26, Xtro\stk24, Xtro\stk3, Xtro\stk25, Xtro\mark2, Xtro\map3k8" "Mmus\Stk24, Mmus\Stk3, Mmus\Stk25, Mmus\Stk4, Mmus\Stk26, Mmus\Mark2, Mmus\Map3k8" "Hsap\STK3, Hsap\MAP3K8, Hsap\STK4, Hsap\STK26, Hsap\STK24, Hsap\STK25" DRSC15729 IE 0.947726084 -2.019776689 -0.819480418 -2.201211832 0.735340256 0.586874372 FBgn0030607 dob doppelganger von brummer http://flybase.org/reports/FBgn0030607 protein_coding_gene triglyceride lipase activity ; GO:0004806 | inferred from biological aspect of ancestor with PANTHER:PTN000274414 triglyceride lipase activity ; GO:0004806 | inferred from sequence or structural similarity with bmm triglyceride catabolic process ; GO:0019433 | inferred from biological aspect of ancestor with PANTHER:PTN000274414 triglyceride catabolic process ; GO:0019433 | inferred from sequence or structural similarity with bmm lipid homeostasis ; GO:0055088 | inferred from biological aspect of ancestor with PANTHER:PTN000274414 lipid particle ; GO:0005811 | inferred from biological aspect of ancestor with PANTHER:PTN000274414 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000274414 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000274414 "dob, CG5560, Dob" "IPR002641:Patatin-like phospholipase domain, IPR016035:Acyl transferase/acyl hydrolase/lysophospholipase, IPR033562:Patatin-like phospholipase domain-containing protein" CG5560 11-Aug-17 DroID_v2017_08 "Drer\pnpla2, Drer\pnpla3" - "Cele\atgl-1, Cele\D1054.1, Cele\B0524.2" "Xtro\pnpla2, Xtro\pnpla3, Xtro\pnpla4" "Mmus\Pnpla2, Mmus\Pnpla5, Mmus\Pnpla1, Mmus\Pnpla3" "Hsap\PNPLA3, Hsap\PNPLA2, Hsap\PNPLA1, Hsap\PNPLA5, Hsap\PNPLA4" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0051915 CG31915 - http://flybase.org/reports/FBgn0051915 protein_coding_gene - - cellular_component ; GO:0005575 | no biological data available "CG6922, CG31915" "IPR002654:Glycosyl transferase, family 25, IPR029044:Nucleotide-diphospho-sugar transferases" CG31915 11-Aug-17 DroID_v2017_08 "Drer\colgalt1, Drer\si:ch211-114l13.7, Drer\si:ch211-13f8.2, Drer\colgalt2, Drer\cercam" - Cele\D2045.9 "Xtro\cercam, Xtro\colgalt1, Xtro\colgalt2" "Mmus\Cercam, Mmus\Colgalt2, Mmus\Colgalt1" "Hsap\COLGALT1, Hsap\COLGALT2, Hsap\CERCAM" viable DRSC03000 K -0.941905526 0.549413336 -0.174662515 0.349777009 0.236452697 2.163769432 FBgn0035965 Use1 Unconventional SNARE in the ER 1 http://flybase.org/reports/FBgn0035965 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with UniProtKB:P53146 "Golgi organization ; GO:0007030 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with SGD:S000003066 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with UniProtKB:P53146 protein secretion ; GO:0009306 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:P53146 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with SGD:S000003066 integral component of cytoplasmic side of endoplasmic reticulum membrane ; GO:0071458 | inferred from sequence or structural similarity with SGD:S000003066 endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG14181, Use1, FBgn 35965" "IPR019150:Vesicle transport protein, Use1" CG14181 11-Aug-17 DroID_v2017_08 "Drer\ccdc78, Drer\ostf1, Drer\use1" Scer\USE1 "Cele\use-1, Cele\Y106G6H.14" "Xtro\use1, Xtro\ostf1" "Mmus\Use1, Mmus\Ostf1" "Hsap\OSTF1, Hsap\USE1" "lethal,neuroanatomy defective" ganglion mother cell DRSC10180 K 0.263451844 0.705092279 1.129383434 0.066709439 -1.09752482 -2.13369899 FBgn0036147 Plod procollagen lysyl hydroxylase http://flybase.org/reports/FBgn0036147 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR006620 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620 growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype" perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG6199, anon-EST:ParkEST325, anon-WO0118547.416, RE-H, Plod, dPlod, LH3" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR029044:Nucleotide-diphospho-sugar transferases" CG6199 11-Aug-17 DroID_v2017_08 "Drer\ogfod2, Drer\plod1a, Drer\plod3, Drer\plod2" - Cele\let-268 "Xtro\plod1, Xtro\plod3, Xtro\ogfod2, Xtro\plod2" "Mmus\Ogfod2, Mmus\Plod3, Mmus\Plod2, Mmus\Plod1" "Hsap\PLOD1, Hsap\OGFOD2, Hsap\PLOD3, Hsap\PLOD2" "viable,fertile" egg FBgn0003884 alphaTub84B alpha-Tubulin at 84B http://flybase.org/reports/FBgn0003884 FBgn0046254 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002452, InterPro:IPR008280, InterPro:IPR017975 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002452 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002452, InterPro:IPR017975 antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from direct assay" astral microtubule ; GO:0000235 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay microtubule ; GO:0005874 | inferred from sequence or structural similarity centrosome ; GO:0005813 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "Tub, alphaTub84B, alpha-tubulin, alpha-Tub, alpha1tub, alphaTUB, CG1913, DM1alpha, ALPHA 84C, clone 2.30, clone 1.59, alpha1, aTub84B, Tubalpha1, Tuba84B, alpha1t, nc33, a1t, T, Talpha1, alphat-1, alphaTub, 1t, tubA84B, alpha84B, DTA1, alphaT, BEST:LD32507, ms(3)nc33, l(3)g3, l(3)84Bd, anon-EST:Liang-2.30, anon-EST:Liang-1.59, alphaTub1, alpha-Tub84B, alphatub, tubulin, tub, alphatub84B, a-tub84B, alphaTub84, alpha-tub84B, alpha-tub, tubalpha1, alpha-tubulin 84B, alpha1tub84B, alphaTUB84B, TBA1_DROME, chr3R:2914276..2914416, Tub1C, Alpha-Tubulin84B, Tub 84B" "IPR000217:Tubulin, IPR002452:Alpha tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain" CG1913 11-Aug-17 DroID_v2017_08 "Drer\tuba8l3, Drer\tuba8l4, Drer\tuba2, Drer\tuba8l, Drer\si:ch73-199e17.1, Drer\tuba7l, Drer\tuba1a, Drer\si:ch211-114n24.6, Drer\tuba4l, Drer\tuba1c, Drer\tuba8l2, Drer\tuba1b" "Scer\TUB3, Scer\TUB1" "Cele\tba-7, Cele\tba-6, Cele\mec-12, Cele\tba-4, Cele\tba-8, Cele\tba-2, Cele\tba-5, Cele\tba-9, Cele\tba-1" "Xtro\tuba1c, Xtro\tuba4b, Xtro\tuba4a, Xtro\tuba1b, Xtro\tuba3e, Xtro\tubal3, Xtro\tuba3c, Xtro\tuba8, Xtro\tuba1a, Xtro\tuba4" "Mmus\Tuba1a, Mmus\Tuba1b, Mmus\Tuba4a, Mmus\Tuba3b, Mmus\Tuba3a, Mmus\Tuba8, Mmus\Tubal3, Mmus\Tuba1c" "Hsap\TUBA3E, Hsap\TUBA8, Hsap\TUBA1C, Hsap\TUBA3C, Hsap\TUBA3D, Hsap\TUBA4A, Hsap\TUBAL3, Hsap\TUBA1A, Hsap\TUBA1B" " adult stage , embryonic stage -- adult stage , larval stage , embryonic stage | 0-12 hr , pupal stage , larval stage | third instar , larval stage | second instar , larval stage | first instar , embryonic stage | 0-21 hr , prepupal stage " " embryonic stage | 16-20 hr , adult stage , larval stage | third instar , embryonic stage | 9-13 hr , pupal stage | mid , embryonic stage | 0-2 hr " " gonad

, adult head

, central nervous system

, imaginal disc

" "lethal,recessive,male semi-sterile,wild-type,male fertile,viable,male sterile,female fertile,poor,partially lethal - majority die,visible" "spermatid,synapse & microtubulehow-24B,mesothoracic tergum" DRSC12622 IE 2.782451514 -1.294286144 4.548484602 -3.53251495 -0.082349808 0.165059518 FBgn0250814 UQCR-C2 Ubiquinol-cytochrome c reductase core protein 2 http://flybase.org/reports/FBgn0250814 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000220169 metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000220169 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:P22695 "protein processing involved in protein targeting to mitochondrion ; GO:0006627 | inferred from biological aspect of ancestor with PANTHER:PTN000747147 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:P22695" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:P22695 mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000747147 "CG4169, anon-EST:Posey245, BEST:GH10978, CG 4169, UCR2, UQCR-C2" "IPR007863:Peptidase M16, C-terminal, IPR011765:Peptidase M16, N-terminal, IPR011249:Metalloenzyme, LuxS/M16 peptidase-like" CG4169 11-Aug-17 DroID_v2017_08 "Drer\uqcrc2a, Drer\uqcrc2b" "Scer\QCR2, Scer\MAS2" "Cele\ucr-2.2, Cele\ucr-2.1, Cele\ucr-2.3" Xtro\uqcrc2 Mmus\Uqcrc2 Hsap\UQCRC2 FBgn0037170 Trxr-2 thioredoxin reductase 2 http://flybase.org/reports/FBgn0037170 protein_coding_gene flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR016156 thioredoxin-disulfide reductase activity ; GO:0004791 | inferred from direct assay thioredoxin-disulfide reductase activity ; GO:0004791 | inferred from sequence or structural similarity with Trxr-1 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR004099, InterPro:IPR012999, InterPro:IPR016156, InterPro:IPR023753 cell redox homeostasis ; GO:0045454 | inferred from sequence or structural similarity with Trxr-1 response to oxygen radical ; GO:0000305 | inferred from biological aspect of ancestor with PANTHER:PTN000530450 cell redox homeostasis ; GO:0045454 | inferred from biological aspect of ancestor with PANTHER:PTN000530450" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN002456835 mitochondrion ; GO:0005739 | inferred from sequence model "trxr-2, Trxr2, DmTrxR-2, CG11401, Trxr-2, Dm-TrxR, DmTrx, TrxR, TRR" "IPR004099:Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, IPR006338:Thioredoxin/glutathione reductase selenoprotein, IPR012999:Pyridine nucleotide-disulphide oxidoreductase, class I, active site, IPR016156:FAD/NAD-linked reductase, dimerisation domain, IPR023753:FAD/NAD(P)-binding domain" CG11401 11-Aug-17 DroID_v2017_08 "Drer\gsr, Drer\si:ch1073-179p4.3, Drer\txnrd1" Scer\GLR1 "Cele\trxr-2, Cele\gsr-1, Cele\trxr-1" "Xtro\txnrd2, Xtro\txnrd3, Xtro\txnrd1, Xtro\gsr" "Mmus\Txnrd3, Mmus\Gsr, Mmus\Txnrd2, Mmus\Txnrd1" "Hsap\TXNRD1, Hsap\TXNRD2, Hsap\GSR, Hsap\TXNRD3" viable FBgn0033055 Tbce Tubulin-specific chaperone E http://flybase.org/reports/FBgn0033055 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype microtubule polymerization ; GO:0046785 | inferred from mutant phenotype inferred from genetic interaction with spas cytoplasm ; GO:0005737 | inferred from direct assay "CG7861, tbce, TBCE, Tbce" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR029071:Ubiquitin-related domain, IPR000938:CAP Gly-rich domain" CG7861 11-Aug-17 DroID_v2017_08 "Drer\tbcelb, Drer\tbce" Scer\PAC2 "Cele\tbcb-1, Cele\tbce-1, Cele\coel-1" "Xtro\tbce, Xtro\tbcel" "Mmus\Tbce, Mmus\Tbcel" "Hsap\TBCE, Hsap\TBCEL" "locomotor behavior defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,lethal - all die before end of pupal stage,some die during pupal stage,viable" "embryonic/larval neuromuscular junction,NMJ bouton,microtubuleC57,microtubule & neuromuscular junction,longitudinal connective,ventral nerve cord,embryonic/larval neuroblast,ganglion mother cell,microtubuleED1484)" FBgn0035140 CG17180 - http://flybase.org/reports/FBgn0035140 protein_coding_gene - - - CG17180 IPR019314:BLOC-1-related complex subunit 6 CG17180 11-Aug-17 DroID_v2017_08 Drer\si:dkey-72l14.4 - Cele\blos-7 - Mmus\Borcs6 Hsap\BORCS6 viable FBgn0029503 CHORD CHORD http://flybase.org/reports/FBgn0029503 protein_coding_gene - regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | inferred from mutant phenotype - "Q9U4A3, chp, CG6198, CHORD, mora, Chord" "IPR007051:CHORD domain, IPR007052:CS domain, IPR008978:HSP20-like chaperone" CG6198 11-Aug-17 DroID_v2017_08 "Drer\zgc:92429, Drer\chordc1a, Drer\chordc1b" - "Cele\chp-1, Cele\D1054.3" "Xtro\itgb1bp2, Xtro\chordc1" "Mmus\Itgb1bp2, Mmus\Chordc1" "Hsap\ITGB1BP2, Hsap\CHORDC1" "mitotic cell cycle defective,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,embryonic/larval salivary gland,testis,condensed chromosome | third instar larval stage,neuroblast,centrosome | third instar larval stage" FBgn0036569 IleRS-m "Isoleucyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0036569 protein_coding_gene "isoleucine-tRNA ligase activity ; GO:0004822 | inferred from electronic annotation with InterPro:IPR002301 tRNA binding ; GO:0000049 | inferred from electronic annotation with InterPro:IPR033708 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002300, InterPro:IPR002301, InterPro:IPR009080 aminoacyl-tRNA editing activity ; GO:0002161 | inferred from electronic annotation with InterPro:IPR009008 isoleucine-tRNA ligase activity ; GO:0004822 | traceable author statement" isoleucyl-tRNA aminoacylation ; GO:0006428 | inferred from electronic annotation with InterPro:IPR002301 isoleucyl-tRNA aminoacylation ; GO:0006428 | traceable author statement cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002301 mitochondrion ; GO:0005739 | traceable author statement "CG5414, IleRS-m" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002300:Aminoacyl-tRNA synthetase, class Ia, IPR002301:Isoleucine-tRNA ligase, IPR009008:Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR013155:Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR033708:Isoleucyl tRNA synthetase type 1, anticodon-binding domain" CG5414 11-Aug-17 DroID_v2017_08 Drer\iars2 Scer\ISM1 Cele\iars-2 Xtro\iars2 Mmus\Iars2 Hsap\IARS2 "viable,visible" trichogen cell FBgn0264753 Rgk1 "Rad, Gem/Kir family member 1" http://flybase.org/reports/FBgn0264753 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from sequence model GTP binding ; GO:0005525 | inferred from sequence model" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 small GTPase mediated signal transduction ; GO:0007264 | inferred from sequence model negative regulation of voltage-gated calcium channel activity ; GO:1901386 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cytoplasmic side of plasma membrane ; GO:0009898 | inferred from sequence model "CG9811, CG30127, CG44011, CT27512, Rgk1, RGK1" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR020849:Small GTPase superfamily, Ras type, IPR021349:Protein of unknown function DUF2967" CG44011 11-Aug-17 DroID_v2017_08 "Drer\rap1aa, Drer\nras, Drer\rit1, Drer\si:dkeyp-59c12.1, Drer\ralab, Drer\rasl11a, Drer\rasl12, Drer\rerglb, Drer\rap2b, Drer\rasl11b, Drer\zgc:153845, Drer\zgc:114118, Drer\ralbb, Drer\rhebl1, Drer\diras2, Drer\rheb, Drer\ralaa, Drer\zgc:171704, Drer\rsg1, Drer\diras1a, Drer\zgc:110699, Drer\hrasb, Drer\rap2ab, Drer\rergla, Drer\LOC100332969, Drer\si:dkey-27j5.5, Drer\zgc:64022, Drer\rem1, Drer\hrasa, Drer\zgc:152698, Drer\rem2, Drer\rras2, Drer\si:ch73-116o1.2, Drer\rap1ab, Drer\kras, Drer\mras, Drer\rap2c, Drer\diras1b, Drer\gem, Drer\rras, Drer\ralba, Drer\rasl10a, Drer\rrad, Drer\rasd1" "Scer\RHB1, Scer\RSR1, Scer\RAS2, Scer\RAS1" "Cele\F20D6.8, Cele\W04C9.5, Cele\rsef-1, Cele\Y52B11A.4" "Xtro\rem1, Xtro\LOC733456, Xtro\nras, Xtro\rergl, Xtro\diras3, Xtro\rhebl1, Xtro\rsg1, Xtro\rasl10a, Xtro\rap2a, Xtro\rheb, Xtro\rem2, Xtro\rap2b, Xtro\kras, Xtro\ras-dva, Xtro\rap1a, Xtro\gem, Xtro\rerg, Xtro\rala, Xtro\diras2, Xtro\diras1, Xtro\rasl11b, Xtro\ralb, Xtro\rap2c, Xtro\rasd2, Xtro\rrad, Xtro\hras, Xtro\rasd1, Xtro\rap1b, Xtro\rit1" "Mmus\Rasd2, Mmus\Rap2b, Mmus\Nras, Mmus\Rhebl1, Mmus\Rasl11a, Mmus\Rasl12, Mmus\Ralb, Mmus\Rasl10a, Mmus\Rem1, Mmus\Rasl10b, Mmus\Rergl, Mmus\Rap1a, Mmus\Rasd1, Mmus\Diras2, Mmus\Rem2, Mmus\Rap2c, Mmus\Diras1, Mmus\Mras, Mmus\Hras, Mmus\Rit2, Mmus\Gm266, Mmus\Eras, Mmus\Rap2a, Mmus\Rsg1, Mmus\Gem, Mmus\Rerg, Mmus\Rala, Mmus\Rasl11b, Mmus\Rras, Mmus\Rrad, Mmus\Rap1b, Mmus\Kras, Mmus\Rras2, Mmus\Rit1, Mmus\Rheb" "Hsap\RRAS, Hsap\RERGL, Hsap\RASL11B, Hsap\RASL10A, Hsap\RAP2C, Hsap\DIRAS3, Hsap\GEM, Hsap\RRAD, Hsap\HRAS, Hsap\RASD1, Hsap\RAP1B, Hsap\RIT1, Hsap\RALB, Hsap\RASD2, Hsap\RRAS2, Hsap\RAP2A, Hsap\REM1, Hsap\RALA, Hsap\ERAS, Hsap\RAP1A, Hsap\REM2, Hsap\RASL10B, Hsap\DIRAS1, Hsap\RIT2, Hsap\DIRAS2, Hsap\RERG, Hsap\RAP2B, Hsap\RHEB, Hsap\NRAS, Hsap\RASL11A, Hsap\RASL12, Hsap\RHEBL1, Hsap\MRAS, Hsap\KRAS, Hsap\RSG1" DRSC05786 I 0.814083046 1.680364897 -0.619960693 -0.133239548 -0.269649279 -0.034355888 FBgn0033679 CG8888 - http://flybase.org/reports/FBgn0033679 protein_coding_gene - - plasma membrane ; GO:0005886 | inferred from direct assay CG8888 "IPR016040:NAD(P)-binding domain, IPR002347:Short-chain dehydrogenase/reductase SDR" CG8888 11-Aug-17 DroID_v2017_08 "Drer\bdh1, Drer\zgc:113142, Drer\rdh5, Drer\hsd17b2, Drer\rdh1, Drer\hsd11b2, Drer\dhrs9, Drer\hsd17b1" "Scer\AYR1, Scer\LYS2" "Cele\drd-5, Cele\dhs-16, Cele\dhs-20, Cele\dhs-2" "Xtro\rdh7, Xtro\LOC100497276, Xtro\rdh5, Xtro\MGC89248, Xtro\rdh16, Xtro\dhrs9, Xtro\LOC100124842, Xtro\hsd17b2, Xtro\hsd11b2, Xtro\rdh7.2, Xtro\LOC100170425, Xtro\hsd17b6, Xtro\bdh1" "Mmus\BC089597, Mmus\Sdr9c7, Mmus\Rdh19, Mmus\Rdh16, Mmus\Dhrs9, Mmus\Bdh1, Mmus\Hsd17b1, Mmus\Rdh1, Mmus\Hsd17b2, Mmus\Rdh7, Mmus\Hsd11b2, Mmus\Hsd17b6, Mmus\Rdh9, Mmus\Rdh5" "Hsap\BDH1, Hsap\RDH5, Hsap\HSD11B2, Hsap\DHRS9, Hsap\HSD17B1, Hsap\SDR9C7, Hsap\HSD17B2, Hsap\HSD17B6, Hsap\RDH16" "viable,fertile" FBgn0035497 CG14995 - http://flybase.org/reports/FBgn0035497 protein_coding_gene - autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern - "CT34848, bs17f06.y1, NEST:bs15f01, NEST:bs17f06, anon-WO0140519.252, CG14995" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG14995 11-Aug-17 DroID_v2017_08 "Drer\si:cabz01080295.1, Drer\lrrc6" - "Cele\F09G8.5, Cele\R02F11.4" Xtro\c21orf2 "Mmus\Lrrc6, Mmus\Cep97, Mmus\1810043G02Rik" "Hsap\C21orf2, Hsap\CEP97, Hsap\LRRC6" "viable,fertile" DRSC22991 K -2.271326693 1.445482122 FBgn0037094 CG7611 - http://flybase.org/reports/FBgn0037094 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9H7D7 "CG7611, WDR26" "IPR001680:WD40 repeat, IPR006594:LIS1 homology motif, IPR006595:CTLH, C-terminal LisH motif, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7611 11-Aug-17 DroID_v2017_08 "Drer\wdr26a, Drer\wdr26b" "Scer\PRP46, Scer\GID7" Cele\Y39H10A.6 Xtro\wdr26 Mmus\Wdr26 Hsap\WDR26 "viable,fertile,visible" "trichogen cell,mesothoracic tergum" DRSC11840 E -0.84929182 -0.109719642 -1.753933469 -1.839069851 -0.143188424 0.844279045 FBgn0034816 CG3085 - http://flybase.org/reports/FBgn0034816 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with SGD:S000002764 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 microtubule nucleation ; GO:0007020 | inferred from sequence or structural similarity with SGD:S000002764 flagellated sperm motility ; GO:0030317 | inferred from biological aspect of ancestor with PANTHER:PTN000462268 cilium movement involved in cell motility ; GO:0060294 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 sperm flagellum ; GO:0036126 | inferred from biological aspect of ancestor with PANTHER:PTN000462268 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 "anon-WO0140519.123, CG3085" IPR000435:Tektin CG3085 11-Aug-17 DroID_v2017_08 "Drer\tekt3, Drer\tekt4, Drer\tekt2, Drer\tekt1" Scer\SPC110 Cele\R02E12.4 "Xtro\tekt3, Xtro\tekt1, Xtro\tekt2, Xtro\tekt4" "Mmus\Tekt1, Mmus\Tekt2, Mmus\Tekt3, Mmus\Tekt4, Mmus\Tekt5" "Hsap\TEKT3, Hsap\TEKT2, Hsap\TEKT4, Hsap\TEKT1, Hsap\TEKT5" viable FBgn0037913 fabp fatty acid binding protein http://flybase.org/reports/FBgn0037913 protein_coding_gene "lipid binding ; GO:0008289 | inferred from electronic annotation with InterPro:IPR000463, InterPro:IPR031259 transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR000463" transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR000463 long-term memory ; GO:0007616 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CT21061, CG31305-PI, CG31305, anon-WO0140519.12, BcDNA:RH46282, BcDNA:SD12036, BcDNA:RH49003, BcDNA:RH06221, anon-EST:Posey234, fabp, CG6783, dFabp, FABP" "IPR000463:Cytosolic fatty-acid binding, IPR000566:Lipocalin/cytosolic fatty-acid binding domain, IPR012674:Calycin, IPR031259:Intracellular lipid binding protein" CG6783 11-Aug-17 DroID_v2017_08 "Drer\fabp1a, Drer\fabp2, Drer\crabp1a, Drer\crabp2a, Drer\fabp11b, Drer\crabp2b, Drer\fabp10a, Drer\rbp7a, Drer\nmnat1, Drer\si:ch211-119o8.7, Drer\rbp1, Drer\rbp2b, Drer\crabp1b, Drer\fabp3, Drer\fabp1b.2, Drer\fabp7a, Drer\fabp7b, Drer\rbp7b, Drer\fabp1b.1, Drer\rbp5, Drer\rbp2a, Drer\fabp6, Drer\fabp10b, Drer\fabp11a" - "Cele\lbp-8, Cele\lbp-6, Cele\lbp-7, Cele\lbp-5, Cele\lbp-9" "Xtro\LOC100145027, Xtro\fabp3, Xtro\rbp2, Xtro\fabp1, Xtro\fabp2, Xtro\rbp5, Xtro\fabp4, Xtro\fabp7, Xtro\pmp2, Xtro\fabp6, Xtro\rbp1, Xtro\crabp2, Xtro\LOC100495473" "Mmus\Rbp2, Mmus\Rbp7, Mmus\Rbp1, Mmus\Fabp2, Mmus\Fabp1, Mmus\Fabp7, Mmus\Crabp1, Mmus\Crabp2, Mmus\Fabp12, Mmus\Fabp5, Mmus\Fabp4, Mmus\Fabp9, Mmus\Fabp6, Mmus\Pmp2, Mmus\Fabp3" "Hsap\RBP2, Hsap\FABP4, Hsap\FABP1, Hsap\RBP5, Hsap\FABP5, Hsap\FABP12, Hsap\PMP2, Hsap\CRABP1, Hsap\FABP6, Hsap\FABP7, Hsap\RBP7, Hsap\CRABP2, Hsap\FABP9, Hsap\FABP3, Hsap\RBP1, Hsap\FABP2" "long lived,RU486 conditional,memory defective,heat sensitive,sleep defective,viable,oxidative stress response defective" "germline cell,male" FBgn0031044 MKP-4 MAPK Phosphatase 4 http://flybase.org/reports/FBgn0031044 protein_coding_gene "protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR016278, InterPro:IPR020422 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement phosphatase activity ; GO:0016791 | inferred from direct assay" "protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR016278, InterPro:IPR020422 protein dephosphorylation ; GO:0006470 | non-traceable author statement dephosphorylation ; GO:0016311 | inferred from direct assay negative regulation of JUN kinase activity ; GO:0043508 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "MKP-4, Mkp4, DMKP-4, CG14211" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR016278:Dual specificity protein phosphatase 12, IPR016130:Protein-tyrosine phosphatase, active site, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like" CG14211 11-Aug-17 DroID_v2017_08 "Drer\dusp3a, Drer\dusp19b, Drer\styx, Drer\ssh1a, Drer\dusp13a, Drer\dusp5, Drer\ssh1b, Drer\ssh2a, Drer\si:ch211-121a2.2, Drer\styxl1, Drer\dusp22a, Drer\dusp3b, Drer\dusp8b, Drer\dusp19a, Drer\dusp2, Drer\dusp10, Drer\si:ch211-223p8.8, Drer\ssh2b, Drer\dusp12, Drer\si:dkey-175m17.7, Drer\dusp16, Drer\dusp22b, Drer\dusp4, Drer\si:ch211-203d1.3" "Scer\PPS1, Scer\MSG5, Scer\YVH1, Scer\SDP1" "Cele\Y54F10BM.13, Cele\C16A3.2, Cele\C24F3.2" "Xtro\dusp1, Xtro\dusp4, Xtro\styx, Xtro\dupd1, Xtro\epm2a, Xtro\dusp26, Xtro\dusp22a, Xtro\dusp12, Xtro\dusp5, Xtro\ssh2, Xtro\dusp22, Xtro\ssh1, Xtro\styxl1, Xtro\dusp19, Xtro\dusp10" "Mmus\Dusp12, Mmus\Styx, Mmus\Dusp10, Mmus\Dusp16, Mmus\Dusp13, Mmus\Ssh1, Mmus\Dusp19, Mmus\Dusp8, Mmus\Ssh3, Mmus\Styxl1, Mmus\Dusp1, Mmus\Dusp2, Mmus\Dusp27, Mmus\Dusp3, Mmus\Epm2a, Mmus\Dupd1, Mmus\Dusp22, Mmus\Dusp26, Mmus\Dusp9, Mmus\Dusp15, Mmus\Dusp4, Mmus\Dusp5, Mmus\Ssh2" "Hsap\DUSP5, Hsap\DUSP15, Hsap\DUSP12, Hsap\DUSP3, Hsap\DUSP22, Hsap\DUPD1, Hsap\DUSP2, Hsap\DUSP8, Hsap\EPM2A, Hsap\DUSP13, Hsap\DUSP16, Hsap\DUSP4, Hsap\DUSP19, Hsap\DUSP9, Hsap\SSH3, Hsap\STYXL1, Hsap\SSH2, Hsap\DUSP26, Hsap\DUSP27, Hsap\DUSP1, Hsap\DUSP10, Hsap\SSH1, Hsap\STYX" viable DRSC19567 E 0.488115098 0.356200806 2.091639881 1.243284881 1.023980776 0.216916257 FBgn0053849 His1:CG33849 His1:CG33849 http://flybase.org/reports/FBgn0053849 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33849, His1:CG33849" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33849 11-Aug-17 DroID_v2017_08 "Drer\histh1l, Drer\si:ch1073-159d7.7, Drer\si:dkey-261m9.12, Drer\si:ch73-36p18.1, Drer\h1fx, Drer\zgc:110216, Drer\h1m, Drer\zgc:110425, Drer\h1f0, Drer\zgc:153405, Drer\si:dkey-108k21.10, Drer\si:ch211-113a14.24, Drer\si:dkey-108k21.14, Drer\si:dkey-108k21.21, Drer\zgc:163061" Scer\HHO1 "Cele\hil-3, Cele\hil-4, Cele\his-24, Cele\hil-1, Cele\hil-5, Cele\hil-2, Cele\hil-6" - "Mmus\H1fnt, Mmus\H1fx, Mmus\Hils1, Mmus\Hist1h1e, Mmus\Hist1h1a, Mmus\Hist1h1t, Mmus\H1foo, Mmus\Hist1h1c, Mmus\Hist1h1b, Mmus\Hist1h1d" "Hsap\HIST1H1D, Hsap\HIST1H1C, Hsap\H1FX, Hsap\H1FOO, Hsap\HIST1H1E, Hsap\H1F0, Hsap\HIST1H1B, Hsap\HIST1H1A, Hsap\H1FNT, Hsap\HIST1H1T" FBgn0035678 CG10469 - http://flybase.org/reports/FBgn0035678 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP123, CG10469" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG10469 11-Aug-17 DroID_v2017_08 "Drer\zgc:92745, Drer\zgc:112368, Drer\si:dkey-78l4.10, Drer\ela3l, Drer\zgc:112285, Drer\masp2, Drer\zgc:112302, Drer\zgc:92041" - Cele\svh-1 - "Mmus\Cela3b, Mmus\F9, Mmus\C1s2, Mmus\Ctrb1, Mmus\Ctrc, Mmus\C1s1, Mmus\Cela1, Mmus\Ctrl, Mmus\Cela3a, Mmus\Prss28, Mmus\Cela2a" "Hsap\C1S, Hsap\PRSS41, Hsap\PRSS55, Hsap\PROC" viable FBgn0015737 Hmu Hemomucin http://flybase.org/reports/FBgn0015737 FBgn0010259 protein_coding_gene "strictosidine synthase activity ; GO:0016844 | inferred from electronic annotation with InterPro:IPR004141, InterPro:IPR018119 hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from biological aspect of ancestor with PANTHER:PTN000046327 receptor activity ; GO:0004872 | non-traceable author statement" "biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004141, InterPro:IPR018119" endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000046327 endomembrane system ; GO:0012505 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000046327 "Hmu, SPH210, RRM5, rrm5, Rbp5, CG3373, hmu" "IPR018119:Strictosidine synthase, conserved region, IPR011042:Six-bladed beta-propeller, TolB-like, IPR004141:Strictosidine synthase" CG3373 11-Aug-17 DroID_v2017_08 "Drer\apmap, Drer\zgc:194209" - "Cele\F57C2.5, Cele\C08E8.2, Cele\T12G3.4" "Xtro\apmap, Xtro\apmap" Mmus\Apmap Hsap\APMAP " embryonic stage&&larval stage&&adult stage , adult stage , adult stage && oogenesis stage " " adult proventriculus

, adult midgut

, ovary

, follicle cell

" " adult stage , adult stage && oogenesis stage " " adult proventriculus

, Malpighian tubule

, hemocyte

, adult midgut

, follicle cell

, ovary

" "viable,visible" mesothoracic tergum FBgn0000032 Acph-1 Acid phosphatase 1 http://flybase.org/reports/FBgn0000032 FBgn0039729 protein_coding_gene acid phosphatase activity ; GO:0003993 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Acph-1 acid phosphatase activity ; GO:0003993 | inferred from sequence or structural similarity with HGNC:125 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:125 dephosphorylation ; GO:0016311 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:125 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:125 "Acph-1, CG7899, ACPH, Acph, ACP, APH" "IPR000560:Histidine phosphatase superfamily, clade-2, IPR029630:Venom acid phosphatase Acph-1, IPR029033:Histidine phosphatase superfamily, IPR033379:Histidine acid phosphatase active site" CG7899 11-Aug-17 DroID_v2017_08 "Drer\pxylp1, Drer\acp2, Drer\acp6" "Scer\PHO11, Scer\PHO12, Scer\DIA3" "Cele\pho-12, Cele\F26C11.1, Cele\ZK809.9, Cele\ZK792.1, Cele\pho-11, Cele\pho-13, Cele\acp-2, Cele\pho-10, Cele\pho-8, Cele\acp-4, Cele\pho-14, Cele\acp-3, Cele\acp-5, Cele\pho-6, Cele\acp-7, Cele\C27A2.12, Cele\pho-1, Cele\acp-6, Cele\acp-1, Cele\pho-5, Cele\pho-4, Cele\pho-9, Cele\pho-7" "Xtro\LOC100494856, Xtro\acp2, Xtro\acp6" "Mmus\Acp6, Mmus\Pxylp1, Mmus\Acpp, Mmus\Acpt, Mmus\Acp2" "Hsap\PXYLP1, Hsap\MINPP1, Hsap\ACP6, Hsap\ACPT, Hsap\ACPP, Hsap\ACP2" embryonic stage -- adult stage "electrophoretic variant,fast,slow,viable,fertile" FBgn0036309 Hip1 Huntingtin interacting protein 1 http://flybase.org/reports/FBgn0036309 protein_coding_gene phospholipid binding ; GO:0005543 | inferred from electronic annotation with InterPro:IPR011417 actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR002558 clathrin binding ; GO:0030276 | inferred from electronic annotation with InterPro:IPR030224 actin binding ; GO:0003779 | inferred from sequence or structural similarity endocytosis ; GO:0006897 | inferred from electronic annotation with InterPro:IPR030224 - "Hip1, CG10971, Hip1R" "IPR002558:I/LWEQ domain, IPR011417:AP180 N-terminal homology (ANTH) domain, IPR030224:Sla2 family, IPR013809:ENTH domain, IPR008942:ENTH/VHS" CG10971 11-Aug-17 DroID_v2017_08 "Drer\hip1, Drer\hip1r, Drer\hip1rb, Drer\hpda, Drer\hpdb" Scer\SLA2 "Cele\C16C8.16, Cele\C31H2.4, Cele\hipr-1, Cele\hpd-1, Cele\Y18D10A.22, Cele\tag-138" "Xtro\hip1r, Xtro\hpd, Xtro\hpd, Xtro\hip1" "Mmus\Hip1, Mmus\Hip1r, Mmus\Hpd" "Hsap\HIP1R, Hsap\HPD, Hsap\HIP1" "visible,viable" "microchaeta & mesothoracic tergumap-md544,microchaeta & mesothoracic tergumpnr-MD237" FBgn0001208 Hn Henna http://flybase.org/reports/FBgn0001208 "FBgn0003737, FBgn0004089, FBgn0005770, FBgn0024922" protein_coding_gene "amino acid binding ; GO:0016597 | inferred from electronic annotation with InterPro:IPR002912 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 phenylalanine 4-monooxygenase activity ; GO:0004505 | inferred from direct assay phenylalanine 4-monooxygenase activity ; GO:0004505 | inferred from mutant phenotype" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR005961, InterPro:IPR018301, InterPro:IPR019773, InterPro:IPR019774 aromatic amino acid family metabolic process ; GO:0009072 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 eye pigment biosynthetic process ; GO:0006726 | inferred from direct assay L-phenylalanine catabolic process ; GO:0006559 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from genetic interaction with Ddc" lipid particle ; GO:0005811 | inferred from direct assay "DTPH, TPH, Tph, PAH, Pah, pah, bu, CG7399, Hn, Trh, TRH, DTPHu" "IPR018301:Aromatic amino acid hydroxylase, iron/copper binding site, IPR001273:Aromatic amino acid hydroxylase, IPR005961:Phenylalanine-4-hydroxylase, tetrameric form, IPR019773:Tyrosine 3-monooxygenase-like, IPR019774:Aromatic amino acid hydroxylase, C-terminal, IPR002912:ACT domain" CG7399 11-Aug-17 DroID_v2017_08 "Drer\pah, Drer\tph2, Drer\th, Drer\th2, Drer\tph1b, Drer\tph1a" - "Cele\tph-1, Cele\cat-2, Cele\pah-1" "Xtro\th, Xtro\pah, Xtro\tph1" "Mmus\Tph1, Mmus\Th, Mmus\Pah, Mmus\Tph2" "Hsap\TPH2, Hsap\TPH1, Hsap\TH, Hsap\PAH" " embryonic stage | 0-6 hr , larval stage | third instar , adult stage , larval stage , embryonic stage--larval stage , embryonic stage | stage 1-11 " " mouthpart

, embryonic/larval fat body

, adult head

, organism

, third instar larval cuticle

" " adult stage , larval stage | third instar , larval stage , pupal stage , embryonic stage | stage 1-11 , larval stage--pupal stage " " adult head

, embryonic/larval fat body

, central nervous system | restricted

, ventral nerve cord | restricted & segmentally repeated

, head

, larval brain | restricted

, neuron &&of ventral nerve cord | medial & segmentally repeated

, organism

, neuron &&of abdominal neuromere | dorso-lateral & segmentally repeated

, neuron &&of ventral nerve cord | ventro-lateral & segmentally repeated

" "eye color defective,recessive,locomotor behavior defective,feeding behavior defective,partially lethal - majority die,some die during embryonic stage,viable,good,visible,lethal,semidominant" "pigment cell,eye" FBgn0032884 Pomp Pomp http://flybase.org/reports/FBgn0032884 protein_coding_gene - proteolysis ; GO:0006508 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from mutant phenotype proteasome assembly ; GO:0043248 | inferred from biological aspect of ancestor with PANTHER:PTN000302763 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000302763 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000302763 proteasome complex ; GO:0000502 | non-traceable author statement "POMP, 38E.20, CG9324, Pomp, pomp, UMP1" IPR008012:Proteasome maturation factor Ump1 CG9324 11-Aug-17 DroID_v2017_08 Drer\pomp Scer\UMP1 Cele\Y57E12AL.6 Xtro\pomp Mmus\Pomp Hsap\POMP DRSC03201 I -3.945383447 -4.010691618 -1.473379134 -1.069049473 0.929175266 0.859726008 FBgn0037297 CG1116 - http://flybase.org/reports/FBgn0037297 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000281946 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000281946 Rab GTPase binding ; GO:0017137 | inferred from sequence or structural similarity with HGNC:21965 "retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN000281946 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:21965 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with HGNC:21965" RIC1-RGP1 guanyl-nucleotide exchange factor complex ; GO:0034066 | inferred from biological aspect of ancestor with PANTHER:PTN000281946 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:21965 Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000281946 "anon-WO0118547.337, CG1116, Rgp1" IPR014848:Reduced growth phenotype protein 1 CG1116 11-Aug-17 DroID_v2017_08 Drer\rgp1 Scer\RGP1 Cele\M01F1.9 Xtro\rgp1 Mmus\Rgp1 Hsap\RGP1 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0053891 His4:CG33891 His4:CG33891 http://flybase.org/reports/FBgn0053891 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33891, His4:CG33891" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33891 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-368j24.14, Drer\zgc:194989, Drer\zgc:153409, Drer\si:ch73-36p18.3, Drer\hist1h4l, Drer\si:dkey-108k21.28, Drer\si:ch211-113a14.6, Drer\si:dkey-23a13.7, Drer\LOC100329358, Drer\LOC570405, Drer\si:dkey-108k21.12, Drer\si:ch211-113a14.26, Drer\LOC794549, Drer\LOC562770, Drer\si:dkey-261m9.18, Drer\si:ch73-368j24.1, Drer\zgc:163040, Drer\si:ch211-113a14.17, Drer\zgc:154164, Drer\si:ch73-36p18.4, Drer\si:dkey-108k21.19, Drer\LOC100150038, Drer\si:dkey-261m9.17, Drer\LOC100331412" "Scer\HHF2, Scer\HHF1" "Cele\his-38, Cele\his-60, Cele\his-31, Cele\his-46, Cele\his-37, Cele\his-10, Cele\his-56, Cele\his-67, Cele\his-18, Cele\his-28, Cele\his-1, Cele\his-14, Cele\his-26, Cele\his-64, Cele\his-5, Cele\his-50" "Xtro\hist1h4c, Xtro\LOC100495739, Xtro\LOC100493041, Xtro\hist1h4k" "Mmus\Hist4h4, Mmus\Hist1h4c, Mmus\Hist1h4h, Mmus\Hist1h4m, Mmus\Hist1h4f, Mmus\Hist1h4i, Mmus\Hist2h4, Mmus\Hist1h4d, Mmus\Hist1h4j, Mmus\Hist1h4a, Mmus\Hist1h4n, Mmus\Hist1h4b, Mmus\Hist1h4k" "Hsap\HIST1H4E, Hsap\HIST1H4L, Hsap\HIST2H4B, Hsap\HIST1H4J, Hsap\HIST1H4D, Hsap\HIST2H4A, Hsap\HIST1H4B, Hsap\HIST1H4K, Hsap\HIST1H4A, Hsap\HIST1H4H, Hsap\HIST1H4I, Hsap\HIST4H4, Hsap\HIST1H4G, Hsap\HIST1H4C, Hsap\HIST1H4F" FBgn0022700 Cht4 Chitinase 4 http://flybase.org/reports/FBgn0022700 "FBgn0034581, FBgn0047078" protein_coding_gene chitin binding ; GO:0008061 | inferred from direct assay chitinase activity ; GO:0004568 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 chitin catabolic process ; GO:0006032 | inferred from direct assay" extracellular space ; GO:0005615 | inferred from direct assay "CHT4, DmCHT4, CG3986, BcDNA:RE62779, Cht4, DmCht4" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR002557:Chitin binding domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG3986 11-Aug-17 DroID_v2017_08 "Drer\srl, Drer\ovgp1, Drer\chia.1, Drer\si:ch211-226m16.2, Drer\chia.5, Drer\chia.3, Drer\chia.2" Scer\CTS2 "Cele\chil-7, Cele\chil-13, Cele\chil-19, Cele\cht-4, Cele\chil-6, Cele\chil-20, Cele\chil-8, Cele\chil-16, Cele\cht-3, Cele\chil-5, Cele\chil-11, Cele\chil-1, Cele\T19H5.6, Cele\lmd-4, Cele\chil-15, Cele\chil-12, Cele\chil-21, Cele\chil-17, Cele\chil-4, Cele\chil-9, Cele\chil-23, Cele\cht-1, Cele\lmd-5, Cele\chil-25, Cele\chil-3, Cele\chil-22, Cele\chil-24, Cele\chil-2, Cele\cht-2, Cele\chil-18" "Xtro\chit1, Xtro\ctbs, Xtro\chia, Xtro\LOC548945, Xtro\srl" "Mmus\Ctbs, Mmus\Chil3, Mmus\Ovgp1, Mmus\Srl, Mmus\Chil5, Mmus\Chia1, Mmus\Chil1, Mmus\Chil6, Mmus\Chit1, Mmus\Chil4" "Hsap\CHIT1, Hsap\CHI3L2, Hsap\SRL, Hsap\CHI3L1, Hsap\OVGP1, Hsap\CHIA" "partially lethal - majority die,some die during pupal stage" DRSC04603 I -1.689241647 -1.058343859 -0.505796038 -0.111866183 -0.388598205 -0.436856432 FBgn0085390 Dgk Diacyl glycerol kinase http://flybase.org/reports/FBgn0085390 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 diacylglycerol kinase activity ; GO:0004143 | non-traceable author statement diacylglycerol kinase activity ; GO:0004143 | inferred from direct assay protein kinase C-activating G-protein coupled receptor signaling pathway ; GO:0007205 | inferred from electronic annotation with InterPro:IPR000756 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 phosphorylation ; GO:0016310 | inferred from direct assay phosphorylation ; GO:0016310 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CG34361, DGKb, CG18654, dDGK, CG1535, Dgk, CG12820, dgk" "IPR018247:EF-Hand 1, calcium-binding site, IPR001206:Diacylglycerol kinase, catalytic domain, IPR000756:Diacylglycerol kinase, accessory domain, IPR002048:EF-hand domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR011992:EF-hand domain pair, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029477:Diacylglycerol kinase type I, N-terminal" CG34361 11-Aug-17 DroID_v2017_08 "Drer\dgkb, Drer\LOC567728, Drer\LOC564739, Drer\dgkaa, Drer\dgke, Drer\dgkab, Drer\dgkq" - Cele\dgk-3 "Xtro\dgkb, Xtro\dgka, Xtro\dgke, Xtro\dgkq" "Mmus\Dgkb, Mmus\Dgkq, Mmus\Dgka, Mmus\Dgkg, Mmus\Dgke" "Hsap\ETV5, Hsap\DGKA, Hsap\DGKQ, Hsap\DGKB, Hsap\DGKE, Hsap\DGKG" " embryonic stage , adult stage " " VUM neuron

, adult brain cortex

, ventral midline

, Bolwig's organ

, mesothoracic extracoxal depressor muscle 66

, retina

, embryonic central nervous system | restricted

, indirect flight muscle

" DRSC05064 IE -1.208573964 -3.453562207 0.094114188 -4.158195097 -0.302043273 -0.552854868 FBgn0053828 His1:CG33828 His1:CG33828 http://flybase.org/reports/FBgn0053828 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33828, His1:CG33828" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33828 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-159d7.7, Drer\h1m, Drer\si:ch73-36p18.1, Drer\zgc:110216, Drer\si:ch211-113a14.24, Drer\si:dkey-261m9.12, Drer\h1fx, Drer\si:dkey-108k21.21, Drer\si:dkey-108k21.14, Drer\zgc:110425, Drer\histh1l, Drer\zgc:163061, Drer\si:dkey-108k21.10, Drer\h1f0, Drer\zgc:153405" Scer\HHO1 "Cele\hil-2, Cele\hil-5, Cele\hil-6, Cele\hil-1, Cele\hil-4, Cele\hil-3, Cele\his-24" - "Mmus\H1foo, Mmus\Hist1h1c, Mmus\H1fx, Mmus\Hist1h1a, Mmus\Hist1h1t, Mmus\H1fnt, Mmus\Hist1h1e, Mmus\Hils1, Mmus\Hist1h1d, Mmus\Hist1h1b" "Hsap\H1FNT, Hsap\H1FX, Hsap\HIST1H1D, Hsap\HIST1H1T, Hsap\HIST1H1C, Hsap\H1F0, Hsap\HIST1H1E, Hsap\H1FOO, Hsap\HIST1H1B, Hsap\HIST1H1A" FBgn0015797 Rab6 Rab6 http://flybase.org/reports/FBgn0015797 "FBgn0010648, FBgn0019647" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with BicD protein binding ; GO:0005515 | inferred from physical interaction with Rich GTPase activity ; GO:0003924 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with CG8578 inferred from physical interaction with TBC1D5 inferred from physical interaction with Evi5 GTPase activity ; GO:0003924 | inferred from direct assay GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 protein binding ; GO:0005515 | inferred from physical interaction with GCC88, cbs" "Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN001178908 R7 cell development ; GO:0045467 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN001178908 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from biological aspect of ancestor with PANTHER:PTN001178908 defense response to fungus ; GO:0050832 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from mutant phenotype regulation of postsynaptic membrane potential ; GO:0060078 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype" neuronal cell body ; GO:0043025 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 synapse ; GO:0045202 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay "Dm Rab6, AAF53168, DmRab6, drab6, CG6601, dRab6, rab6, l(2)08323, wrt, Drab6, 136/6, DRab6, Rab6, O18334" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG6601 11-Aug-17 DroID_v2017_08 "Drer\rab6bb, Drer\rab6ba, Drer\rab34b, Drer\rab36, Drer\rab34a, Drer\rab6a, Drer\rab41" Scer\YPT6 "Cele\F20D6.8, Cele\rab-6.1, Cele\rab-6.2, Cele\Y71H2AM.12, Cele\W04C9.5" "Xtro\rab36, Xtro\rab34, Xtro\rab6a" "Mmus\Rab36, Mmus\Rab34, Mmus\Rab6a, Mmus\Rab6b" "Hsap\RAB6B, Hsap\RAB36, Hsap\WTH3DI, Hsap\RAB6A, Hsap\RAB41, Hsap\RAB6C, Hsap\RAB34" "visible,recessive,viable,immune response defective,dominant,lethal,cell non-autonomous,somatic clone,lethal - all die before end of larval stage,some die during larval stage,neurophysiology defective,wild-type" "macrochaeta,hemocyte,cell non-autonomous,somatic clone,adult head & microchaeta | somatic clone | cell non-autonomous,adult thorax & microchaeta | somatic clone | cell non-autonomous,retina,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,interocellar bristle,scutellar bristle,scutum & macrochaeta,actin cytoskeleton & egg chamber | germ-line clone,Golgi apparatus & egg chamber | germ-line clone,microtubule cytoskeleton & egg chamber | germ-line clone,egg chamber,germline clone,photoreceptor cell R7" FBgn0039310 CG11878 - http://flybase.org/reports/FBgn0039310 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CT33083, CG11878" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG11878 11-Aug-17 DroID_v2017_08 - - "Cele\F58B4.5, Cele\E02C12.9, Cele\E02C12.6, Cele\nhr-246, Cele\H37A05.2, Cele\dhs-27, Cele\C29F7.2, Cele\E02C12.8, Cele\H06H21.8, Cele\F56A4.5, Cele\Y45G12C.4, Cele\C18B10.6, Cele\C29F7.1, Cele\E02C12.10" - - - viable FBgn0067864 Patj Patj http://flybase.org/reports/FBgn0067864 protein_coding_gene protein kinase C binding ; GO:0005080 | inferred from physical interaction with aPKC myosin II light chain binding ; GO:0032033 | inferred from direct assay establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement apical protein localization ; GO:0045176 | traceable author statement establishment or maintenance of polarity of embryonic epithelium ; GO:0016332 | traceable author statement establishment or maintenance of polarity of follicular epithelium ; GO:0016334 | inferred from physical interaction with crb adherens junction organization ; GO:0034332 | inferred from mutant phenotype morphogenesis of follicular epithelium ; GO:0016333 | inferred from mutant phenotype pupal development ; GO:0035209 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype zonula adherens assembly ; GO:0045186 | non-traceable author statement morphogenesis of an epithelium ; GO:0002009 | traceable author statement negative regulation of myosin-light-chain-phosphatase activity ; GO:0035509 | inferred from genetic interaction with Mbs photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype adherens junction maintenance ; GO:0034334 | inferred from genetic interaction with shg establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype establishment or maintenance of apical/basal cell polarity ; GO:0035088 | inferred from mutant phenotype cell-cell junction assembly ; GO:0007043 | non-traceable author statement establishment or maintenance of neuroblast polarity ; GO:0045196 | NOT inferred from mutant phenotype plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay subapical complex ; GO:0035003 | inferred from direct assay plasma membrane ; GO:0005886 | non-traceable author statement subapical complex ; GO:0035003 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay nuclear envelope ; GO:0005635 | non-traceable author statement apical cortex ; GO:0045179 | non-traceable author statement adherens junction ; GO:0005912 | inferred from direct assay septate junction ; GO:0005918 | traceable author statement apicolateral plasma membrane ; GO:0016327 | inferred from direct assay apical plasma membrane ; GO:0016324 | non-traceable author statement "Patj, D-Patj, DPATJ, dPatj, dlt, Dlt, DLT, CG12021, dlt:discs lost, DPatj, BcDNA:LD22238, PATJ, PatJ, patj, PaTJ, Dpatj, Patj/Dlt, dPATJ, dpatj" "IPR001478:PDZ domain, IPR004172:L27 domain" CG12021 11-Aug-17 DroID_v2017_08 "Drer\grip1, Drer\taar13e, Drer\si:dkey-92i15.4, Drer\pard3bb, Drer\pdzd7b, Drer\il16, Drer\dlg5a, Drer\lnx1, Drer\inadl, Drer\slc9a3r1, Drer\grip2b, Drer\grid2ipa" - "Cele\magi-1, Cele\dlg-1, Cele\mpz-1" "Xtro\grip2, Xtro\grid2ip, Xtro\dlg5, Xtro\grip1, Xtro\lnx1" "Mmus\Dlg5, Mmus\Il16, Mmus\Grip1, Mmus\Pdzd11, Mmus\Grasp, Mmus\Mpdz, Mmus\Pdzd2, Mmus\Patj, Mmus\Grip2, Mmus\Pdzph1, Mmus\Lnx1, Mmus\Ush1c, Mmus\Grid2ip" "Hsap\GRASP, Hsap\IL16, Hsap\LNX1, Hsap\TJP1, Hsap\PATJ, Hsap\GRIP1, Hsap\MPDZ, Hsap\PARD3B, Hsap\FRMPD2, Hsap\USH1C, Hsap\PDZD2, Hsap\GRID2IP, Hsap\DLG5" pupal stage photoreceptor cell stalk | apical

"lethal,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,germline clone,cell polarity defective,somatic clone,visible" "embryonic/first instar larval cuticle,follicle cell,somatic clone,ectoderm,photoreceptor,pupa,head,pupal thorax,imaginal disc" FBgn0053829 His2A:CG33829 His2A:CG33829 http://flybase.org/reports/FBgn0053829 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33829, His2A:CG33829" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33829 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.19, Drer\si:ch211-113a14.26, Drer\zgc:101846, Drer\fbxl6, Drer\zgc:114037, Drer\LOC100334934, Drer\si:ch211-113a14.19, Drer\LOC100148591, Drer\zgc:173652, Drer\si:ch211-113a14.16, Drer\si:dkey-261m9.11, Drer\si:dkey-23a13.14, Drer\h2afx, Drer\zgc:110434, Drer\zgc:195633, Drer\si:dkey-23a13.20, Drer\si:ch211-113a14.11, Drer\zgc:154164, Drer\zgc:165551, Drer\si:ch211-113a14.7, Drer\si:ch1073-159d7.11, Drer\si:dkey-108k21.15, Drer\si:ch1073-159d7.10, Drer\si:dkey-261m9.7, Drer\si:dkey-108k21.26, Drer\si:ch73-368j24.15, Drer\LOC570115, Drer\h2afy2, Drer\si:dkey-261m9.18, Drer\si:ch1073-153i20.5, Drer\si:dkey-23a13.7, Drer\si:dkey-261m9.15, Drer\si:ch73-368j24.13, Drer\LOC100332229, Drer\si:ch1073-159d7.9, Drer\si:ch73-36p18.5, Drer\si:ch73-368j24.14" "Scer\HTA1, Scer\HTA2" "Cele\his-21, Cele\his-43, Cele\his-35, Cele\his-3, Cele\his-47, Cele\his-12, Cele\his-16, Cele\his-65, Cele\his-19, Cele\his-61, Cele\his-7, Cele\his-33, Cele\his-53, Cele\his-57, Cele\his-51, Cele\htas-1, Cele\his-30, Cele\his-68" "Xtro\hist1h2ad, Xtro\hist1h2aj, Xtro\hist1h2ah, Xtro\hist1h2am, Xtro\h2afx, Xtro\h2afj, Xtro\h2afy2, Xtro\h2afy, Xtro\hist1h2aa" "Mmus\Gm14920, Mmus\H2al2b, Mmus\H2afx, Mmus\Hist1h2ac, Mmus\Hist1h2an, Mmus\Hist2h2aa2, Mmus\Hist1h2ad, Mmus\Hist2h2ab, Mmus\Hist1h2ae, Mmus\Hist1h2ak, Mmus\H2al1n, Mmus\Hist1h2ah, Mmus\H2afb3, Mmus\H2afy, Mmus\H2afb2, Mmus\Hist1h2aa, Mmus\Hist1h2ag, Mmus\Hist3h2a, Mmus\H2afy2, Mmus\Hist1h2ai, Mmus\Hist1h2ao, Mmus\H2afj, Mmus\Hist2h2ac, Mmus\Hist1h2ap, Mmus\H2al1j, Mmus\H2afb1, Mmus\Hist1h2ab, Mmus\Hist1h2af, Mmus\H2al2c, Mmus\Hist2h2aa1" "Hsap\H2AFJ, Hsap\H2AFY2, Hsap\HIST2H2AA3, Hsap\HIST1H2AJ, Hsap\HIST1H2AE, Hsap\HIST1H2AG, Hsap\HIST2H2AC, Hsap\HIST2H2AA4, Hsap\HIST1H2AM, Hsap\HIST1H2AK, Hsap\H2AFY, Hsap\H2AFX, Hsap\H2AFB1, Hsap\H2AFB3, Hsap\HIST1H2AD, Hsap\HIST1H2AB, Hsap\HIST1H2AI, Hsap\HIST1H2AC, Hsap\HIST1H2AA, Hsap\HIST3H2A, Hsap\H2AFB2, Hsap\HIST2H2AB, Hsap\HIST1H2AH, Hsap\HIST1H2AL" FBgn0053819 His1:CG33819 His1:CG33819 http://flybase.org/reports/FBgn0053819 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33819, His1:CG33819" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33819 11-Aug-17 DroID_v2017_08 "Drer\zgc:153405, Drer\si:dkey-108k21.10, Drer\h1f0, Drer\zgc:110425, Drer\si:ch1073-159d7.7, Drer\h1fx, Drer\si:ch73-36p18.1, Drer\histh1l, Drer\si:dkey-108k21.21, Drer\si:ch211-113a14.24, Drer\si:dkey-261m9.12, Drer\h1m, Drer\zgc:110216, Drer\zgc:163061, Drer\si:dkey-108k21.14" Scer\HHO1 "Cele\his-24, Cele\hil-6, Cele\hil-5, Cele\hil-2, Cele\hil-4, Cele\hil-1, Cele\hil-3" - "Mmus\Hist1h1d, Mmus\Hist1h1t, Mmus\Hils1, Mmus\Hist1h1b, Mmus\Hist1h1a, Mmus\Hist1h1c, Mmus\H1foo, Mmus\H1fnt, Mmus\Hist1h1e, Mmus\H1fx" "Hsap\HIST1H1E, Hsap\HIST1H1B, Hsap\HIST1H1A, Hsap\H1FX, Hsap\HIST1H1T, Hsap\HIST1H1D, Hsap\HIST1H1C, Hsap\H1FNT, Hsap\H1F0, Hsap\H1FOO" FBgn0039293 CG11851 - http://flybase.org/reports/FBgn0039293 protein_coding_gene mannosyltransferase activity ; GO:0000030 | inferred from biological aspect of ancestor with PANTHER:PTN000509188 - endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000509188 endomembrane system ; GO:0012505 | inferred from direct assay "CG11851, dAlg9" IPR005599:GPI mannosyltransferase CG11851 11-Aug-17 DroID_v2017_08 Drer\alg9 Scer\ALG9 Cele\C14A4.3 Xtro\alg9 "Mmus\Fdxacb1, Mmus\Alg9" "Hsap\ALG9, Hsap\FDXACB1" viable DRSC14407 K -0.204322353 -0.455114228 0.297194715 1.497654701 2.0975499 0.3926273 FBgn0051548 CG31548 - http://flybase.org/reports/FBgn0051548 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "CG2907, BcDNA:RH24570, CG31548" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG31548 11-Aug-17 DroID_v2017_08 "Drer\elovl4b, Drer\hsd17b14, Drer\elovl8a, Drer\elovl2, Drer\hsdl2, Drer\pecr, Drer\dhrs7, Drer\decr1, Drer\elovl1b, Drer\bdh2, Drer\zgc:101858, Drer\hsd17b8, Drer\elovl4a, Drer\elovl5, Drer\elovl8b, Drer\elovl7a, Drer\decr2, Drer\dhrs1, Drer\cbr4, Drer\elovl7b, Drer\elovl1a, Drer\zgc:113054" "Scer\SPS19, Scer\YIR035C, Scer\IRC24, Scer\OAR1" "Cele\dhs-14, Cele\Y47G6A.21, Cele\ZK829.1, Cele\F25D1.5, Cele\C06E4.3, Cele\Y47G6A.22, Cele\dhs-25, Cele\F28H7.2, Cele\dhs-23, Cele\F26D2.15, Cele\dhs-11" "Xtro\cbr4, Xtro\elovl5, Xtro\hsd17b14, Xtro\elovl7, Xtro\pecr, Xtro\MGC147226, Xtro\decr1, Xtro\hsd17b8, Xtro\decr2, Xtro\dhrs7, Xtro\MGC79752, Xtro\hsdl2, Xtro\elovl1, Xtro\dhrs4, Xtro\elovl2" "Mmus\Hsdl2, Mmus\Dhrs7, Mmus\Dhrs2, Mmus\Elovl2, Mmus\Elovl7, Mmus\Pecr, Mmus\Elovl4, Mmus\Dhrs1, Mmus\Bdh2, Mmus\Hsd17b14, Mmus\Cbr4, Mmus\Elovl5, Mmus\Decr2, Mmus\Dhrs4, Mmus\H2-Ke6, Mmus\Decr1" "Hsap\BDH2, Hsap\DHRS4, Hsap\ELOVL2, Hsap\PECR, Hsap\ELOVL4, Hsap\HSDL2, Hsap\ELOVL1, Hsap\DHRS4L2, Hsap\HSD17B8, Hsap\CBR4, Hsap\ELOVL7, Hsap\HSD17B14, Hsap\DECR2, Hsap\DHRS7, Hsap\DHRS1, Hsap\DHRS2, Hsap\DECR1, Hsap\ELOVL5" viable DRSC22640 K 0.330891797 1.236446305 1.451716451 1.454624192 -0.538102295 1.727757547 FBgn0034967 eEF5 eukaryotic translation elongation factor 5 http://flybase.org/reports/FBgn0034967 protein_coding_gene "ribosome binding ; GO:0043022 | inferred from electronic annotation with InterPro:IPR001884, InterPro:IPR019769, InterPro:IPR020189 translation elongation factor activity ; GO:0003746 | inferred from mutant phenotype translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with SGD:S000000760" "translational frameshifting ; GO:0006452 | inferred from electronic annotation with InterPro:IPR019769, InterPro:IPR020189 positive regulation of translational termination ; GO:0045905 | inferred from electronic annotation with InterPro:IPR001884, InterPro:IPR019769, InterPro:IPR020189 positive regulation of translational elongation ; GO:0045901 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern positive regulation of translational elongation ; GO:0045901 | inferred from sequence or structural similarity with SGD:S000000760 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000760 "CG3186, l(2)01296, 1296, anon-EST:fe2H10, eIF-5A, eIF5a, eIF5A, chr2R:19566878..19566998, eEF5" "IPR001884:Translation elongation factor IF5A, IPR008991:Translation protein SH3-like domain, IPR012340:Nucleic acid-binding, OB-fold, IPR014722:Ribosomal protein L2 domain 2, IPR019769:Translation elongation factor, IF5A, hypusine site, IPR020189:Translation elongation factor, IF5A C-terminal" CG3186 11-Aug-17 DroID_v2017_08 "Drer\eif5a, Drer\eif5a2" "Scer\HYP2, Scer\ANB1" "Cele\iff-2, Cele\iff-1" Xtro\eif5a "Mmus\Eif5a, Mmus\Eif5a2" "Hsap\EIF5A2, Hsap\EIF5AL1, Hsap\EIF5A" "lethal,recessive,decreased cell size" "embryonic/larval fat body,wing cell,macrochaeta" DRSC04681 I -1.299462514 1.570271148 0.90889297 -1.175657152 0.239886116 0.200399905 FBgn0262125 Sec23 Secretory 23 http://flybase.org/reports/FBgn0262125 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006895 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with SGD:S000006385 "positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype basement membrane organization ; GO:0071711 | inferred from mutant phenotype regulation of COPII vesicle coating ; GO:0003400 | inferred from sequence or structural similarity with SGD:S000006385 Golgi organization ; GO:0007030 | inferred from genetic interaction with ecd positive regulation of cuticle pigmentation ; GO:0048081 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype protein localization to cell surface ; GO:0034394 | inferred from mutant phenotype positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype positive regulation of extracellular matrix constituent secretion ; GO:0003331 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype maintenance of cell polarity ; GO:0030011 | inferred from mutant phenotype larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with SGD:S000006385 Golgi organization ; GO:0007030 | inferred from mutant phenotype protein targeting to plasma membrane ; GO:0072661 | inferred from mutant phenotype" COPII vesicle coat ; GO:0030127 | inferred from sequence or structural similarity with SGD:S000006385 endoplasmic reticulum exit site ; GO:0070971 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay ER to Golgi transport vesicle ; GO:0030134 | traceable author statement Golgi stack ; GO:0005795 | inferred from direct assay "COPII, sec23, Sec23, CG1250, hau, dsec23p, dSec23p, dsec23, dSec23, Sec23A, dar2, SEC23, Sec23p" "IPR002035:von Willebrand factor, type A, IPR029006:ADF-H/Gelsolin-like domain, IPR006895:Zinc finger, Sec23/Sec24-type, IPR006896:Sec23/Sec24, trunk domain, IPR006900:Sec23/Sec24, helical domain, IPR007123:Gelsolin-like domain, IPR012990:Sec23/Sec24 beta-sandwich" CG1250 11-Aug-17 DroID_v2017_08 "Drer\sec23b, Drer\sec23a" "Scer\SEC23, Scer\NEL1" Cele\sec-23 "Xtro\sec23b, Xtro\sec23a" "Mmus\Sec23b, Mmus\Sec23a" "Hsap\SEC23B, Hsap\SEC23A" DRSC12387 E -0.240496034 0.187126173 1.525756143 0.053635107 0.475701515 -0.148150551 FBgn0030558 CG1461 - http://flybase.org/reports/FBgn0030558 protein_coding_gene "L-tyrosine:2-oxoglutarate aminotransferase activity ; GO:0004838 | inferred from electronic annotation with InterPro:IPR005957 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004838, InterPro:IPR004839, InterPro:IPR005957, InterPro:IPR005958" "aromatic amino acid family metabolic process ; GO:0009072 | inferred from electronic annotation with InterPro:IPR005957 biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004838, InterPro:IPR004839 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR005958" - "CG1461, cg1461" "IPR004838:Aminotransferases, class-I, pyridoxal-phosphate-binding site, IPR004839:Aminotransferase, class I/classII, IPR005957:Tyrosine aminotransferase, IPR005958:Tyrosine/nicotianamine aminotransferase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG1461 11-Aug-17 DroID_v2017_08 Drer\tat "Scer\HIS5, Scer\BNA3" Cele\tatn-1 Xtro\tat Mmus\Tat Hsap\TAT FBgn0035499 Chd64 Chd64 http://flybase.org/reports/FBgn0035499 protein_coding_gene juvenile hormone response element binding ; GO:0070594 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with FK506-bp1 smooth muscle contraction ; GO:0006939 | inferred from sequence or structural similarity juvenile hormone mediated signaling pathway ; GO:0035626 | inferred from mutant phenotype striated muscle thin filament ; GO:0005865 | inferred from sequence or structural similarity "Chd64, CT34849, CG14996, clone 1.80, anon-EST:Liang-1.80, CG-14996" "IPR000557:Calponin repeat, IPR001715:Calponin homology domain, IPR003096:Smooth muscle protein/calponin" CG14996 11-Aug-17 DroID_v2017_08 "Drer\tagln3a, Drer\cnn3a, Drer\cnn2, Drer\cnn1b, Drer\tagln, Drer\tagln2, Drer\cnn3b, Drer\iqgap2, Drer\cnn1a, Drer\tagln3b" "Scer\IQG1, Scer\SCP1" "Cele\pes-7, Cele\cpn-3, Cele\clik-1, Cele\unc-87, Cele\cpn-2, Cele\K03E5.2, Cele\cpn-1, Cele\cpn-4, Cele\C53C9.2" "Xtro\tagln2, Xtro\tagln, Xtro\cnn1, Xtro\cnn2, Xtro\cnn3" "Mmus\Tagln, Mmus\Cnn2, Mmus\Cnn3, Mmus\Tagln2, Mmus\Iqgap1, Mmus\Cnn1, Mmus\Tagln3, Mmus\Iqgap3" "Hsap\CNN1, Hsap\TAGLN, Hsap\IQGAP1, Hsap\TAGLN3, Hsap\IQGAP3, Hsap\CNN3, Hsap\TAGLN2, Hsap\CNN2" "viable,sleep defective,partially lethal - majority die,some die during pupal stage" FBgn0010380 AP-1-2beta "Adaptor Protein complex 1/2, beta subunit" http://flybase.org/reports/FBgn0010380 - protein_coding_gene protein transporter activity ; GO:0008565 | inferred from electronic annotation with InterPro:IPR016342 protein transporter activity ; GO:0008565 | inferred by curator from GO:0030119 "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR008152, InterPro:IPR009028, InterPro:IPR013037, InterPro:IPR015151 vesicle-mediated transport ; GO:0016192 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR008152, InterPro:IPR009028, InterPro:IPR013037, InterPro:IPR015151, InterPro:IPR026739 vesicle-mediated transport ; GO:0016192 | inferred by curator from GO:0030119 neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle coating ; GO:0016183 | traceable author statement vesicle coating ; GO:0006901 | traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype" synaptic vesicle ; GO:0008021 | traceable author statement trans-Golgi network ; GO:0005802 | inferred from direct assay coated vesicle ; GO:0030135 | traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay clathrin-coated pit ; GO:0005905 | inferred from direct assay clathrin-coated vesicle ; GO:0030136 | inferred from direct assay AP-2 adaptor complex ; GO:0030122 | inferred from sequence or structural similarity with SGD:S000003765 AP-type membrane coat adaptor complex ; GO:0030119 | inferred from direct assay "CG12532, AP-beta1, cg12532, beta1/2, bap, AP-2beta, BAD1, Bap, AP-1-2beta, AP-1beta1, apl1, Beta-adaptin, AP-1/2beta, BAP, AP1beta1, AP2beta2, apl2, beta2-ada" "IPR002553:Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR008152:Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain, IPR009028:Coatomer/calthrin adaptor appendage, C-terminal subdomain, IPR011989:Armadillo-like helical, IPR013037:Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain, IPR013041:Coatomer/clathrin adaptor appendage, Ig-like subdomain, IPR015151:Beta-adaptin appendage, C-terminal subdomain, IPR016024:Armadillo-type fold, IPR016342:AP-1, 2,4 complex subunit beta, IPR026739:AP complex subunit beta" CG12532 11-Aug-17 DroID_v2017_08 "Drer\ap1b1, Drer\ap4b1, Drer\ap2b1" "Scer\APL2, Scer\APL1" Cele\apb-1 "Xtro\ap4b1, Xtro\ap2b1, Xtro\ap1b1" "Mmus\Ap1b1, Mmus\Ap2b1, Mmus\Ap4b1" "Hsap\AP1B1, Hsap\AP4B1, Hsap\AP2B1" "lethal - all die before end of pupal stage,some die during pupal stage,lethal" eye DRSC19336 I -0.816838589 1.782481382 -0.26857113 0.621565412 -0.080638364 -0.080004144 FBgn0036928 Tom20 Translocase of outer membrane 20 http://flybase.org/reports/FBgn0036928 protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000277108 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 mitochondrion targeting sequence binding ; GO:0030943 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:Q15388 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 tRNA import into mitochondrion ; GO:0016031 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 mitochondrial outer membrane translocase complex assembly ; GO:0070096 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q15388 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from sequence or structural similarity with UniProtKB:Q15388 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 mitochondrion ; GO:0005739 | inferred from direct assay integral component of mitochondrial outer membrane ; GO:0031307 | inferred from biological aspect of ancestor with PANTHER:PTN000277108 "CG7654, dtom20, anon-WO0118547.225, Tom20, TOM20, TOM 20, tom20" "IPR002056:Protein import receptor MAS20, IPR023392:Mitochondrial outer membrane translocase complex, subunit Tom20 domain, IPR022422:Protein import receptor MAS20, metazoan" CG7654 11-Aug-17 DroID_v2017_08 "Drer\tomm20b, Drer\tomm20a" Scer\TOM20 "Cele\F32B4.2, Cele\tomm-20" Xtro\tomm20 "Mmus\Tomm20l, Mmus\Tomm20" "Hsap\TOMM20, Hsap\TOMM20L" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0036967 SCCRO4 Squamous cell carcinoma-related oncogene 4 http://flybase.org/reports/FBgn0036967 protein_coding_gene ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 ubiquitin-like protein binding ; GO:0032182 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 cullin family protein binding ; GO:0097602 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 negative regulation of protein neddylation ; GO:2000435 | inferred from mutant phenotype positive regulation of ubiquitin-protein transferase activity ; GO:0051443 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000264493 nucleus ; GO:0005634 | inferred from direct assay "CG6597, dSCCRO4, SCCRO4" "IPR005176:Potentiating neddylation domain, IPR014764:Defective-in-cullin neddylation protein" CG6597 11-Aug-17 DroID_v2017_08 "Drer\dcun1d5, Drer\dcun1d4, Drer\dcun1d2b, Drer\dcun1d3, Drer\dcun1d1" Scer\DCN1 Cele\dcn-1 "Xtro\dcun1d3, Xtro\dcun1d2, Xtro\dcun1d5" "Mmus\Dcun1d2, Mmus\Dcun1d3, Mmus\Dcun1d4, Mmus\Dcun1d1, Mmus\Dcun1d5" "Hsap\DCUN1D1, Hsap\DCUN1D2, Hsap\DCUN1D3, Hsap\DCUN1D4, Hsap\DCUN1D5" viable FBgn0046332 gskt gasket http://flybase.org/reports/FBgn0046332 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:4617" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:4617 male gamete generation ; GO:0048232 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:4617 "CG31003, NGSK, GSK3b, CT4237, CG11338, mjl, BEST:GH16447, NEST:bs22e06, Gsk3b, BcDNA:AT21229, gskt, Gskt, Dm Gskt" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG31003 11-Aug-17 DroID_v2017_08 "Drer\si:dkeyp-80c12.7, Drer\gsk3aa, Drer\gsk3b, Drer\gsk3ab" "Scer\YGK3, Scer\MRK1, Scer\RIM11, Scer\MCK1" "Cele\R03D7.5, Cele\gsk-3, Cele\C44H4.6" "Xtro\gsk3b, Xtro\gsk3a" "Mmus\Gsk3a, Mmus\Gsk3b" "Hsap\GSK3A, Hsap\GSK3B" "viable,visible,male sterile germline-dependent" "trichogen cell,wing margin" FBgn0033277 CG14760 - http://flybase.org/reports/FBgn0033277 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP120, CG14760" "IPR000859:CUB domain, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site" CG14760 11-Aug-17 DroID_v2017_08 Drer\proca - Cele\svh-1 - "Mmus\Proc, Mmus\Tmprss7, Mmus\St14, Mmus\Tmprss6, Mmus\F9, Mmus\F10" "Hsap\PROC, Hsap\ST14, Hsap\TMPRSS6, Hsap\TMPRSS7, Hsap\F10" viable FBgn0010352 Nc73EF Neural conserved at 73EF http://flybase.org/reports/FBgn0010352 "FBgn0036682, FBgn0062089" protein_coding_gene thiamine pyrophosphate binding ; GO:0030976 | inferred from electronic annotation with InterPro:IPR011603 oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591 | inferred from sequence or structural similarity with UniProtKB:Q02218 oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591 | inferred from biological aspect of ancestor with PANTHER:PTN000568211 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:Q02218 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000568211 mitochondrial oxoglutarate dehydrogenase complex ; GO:0009353 | inferred from sequence or structural similarity with UniProtKB:Q02218 oxoglutarate dehydrogenase complex ; GO:0045252 | inferred from biological aspect of ancestor with PANTHER:PTN000568211 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000568260 microtubule associated complex ; GO:0005875 | inferred from direct assay "141810_at, FBgn0036682, CG11661, anon-WO0118547.329, Nc73EF, E1, Nc73eF, dOgdh, DOGDH" "IPR001017:Dehydrogenase, E1 component, IPR005475:Transketolase-like, pyrimidine-binding domain, IPR011603:2-oxoglutarate dehydrogenase E1 component, IPR029061:Thiamin diphosphate-binding fold, IPR032106:2-oxoglutarate dehydrogenase E1 component, N-terminal domain, IPR031717:Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal" CG11661 11-Aug-17 DroID_v2017_08 "Drer\ogdha, Drer\ogdhb, Drer\ogdhl, Drer\dhtkd1" Scer\KGD1 "Cele\ZK836.2, Cele\ogdh-1" "Xtro\dhtkd1, Xtro\ogdh, Xtro\ogdhl" "Mmus\Ogdh, Mmus\Dhtkd1, Mmus\Ogdhl" "Hsap\OGDHL, Hsap\OGDH, Hsap\DHTKD1" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0010408 RpS9 Ribosomal protein S9 http://flybase.org/reports/FBgn0010408 - protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000216478 structural constituent of ribosome ; GO:0003735 | inferred from direct assay cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement positive regulation of translational fidelity ; GO:0045903 | inferred from biological aspect of ancestor with PANTHER:PTN000216478 small ribosomal subunit ; GO:0015935 | inferred from electronic annotation with InterPro:IPR005710 cytosol ; GO:0005829 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "RpS9, RpL11, CG3395, S9, Rp S9, chr3L:9483841..9483937, chr3L:9484246..9484474, RPS9" "IPR018079:Ribosomal protein S4, conserved site, IPR001912:Ribosomal protein S4/S9, N-terminal, IPR002942:RNA-binding S4 domain, IPR005710:Ribosomal protein S4/S9, eukaryotic/archaeal, IPR022801:Ribosomal protein S4/S9" CG3395 11-Aug-17 DroID_v2017_08 Drer\rps9 "Scer\RPS9A, Scer\RPS9B" Cele\rps-9 Xtro\rps9 Mmus\Rps9 Hsap\RPS9 "viable,fertile,Minute" DRSC11273 EK -0.562962742 0.04905849 2.88019009 -4.012587506 1.31556559 4.6632144 FBgn0039812 CG15548 - http://flybase.org/reports/FBgn0039812 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15548 "IPR031936:Domain of unknown function DUF4771, IPR031935:Domain of unknown function DUF4770" CG15548 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC15086 E 0.33824122 -0.062562998 0.11468095 -1.54741454 0.469707313 0.034597307 FBgn0265296 Dscam2 Down syndrome cell adhesion molecule 2 http://flybase.org/reports/FBgn0265296 protein_coding_gene identical protein binding ; GO:0042802 | inferred from physical interaction with Dscam2 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from sequence or structural similarity with UniProtKB:Q8TD84 homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR033027 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Dscam2, CG17742, CG32389, CG32387, CG42256, Dscam-like, CT34644, CT14580, BcDNA:AT03867, CG8618, CG14828, CT14584, CG8619" "IPR033027:Down syndrome cell adhesion molecule, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG42256 11-Aug-17 DroID_v2017_08 "Drer\mylk3, Drer\lrit1a, Drer\sdk1a, Drer\kirrel3a, Drer\LOC799279, Drer\kirrelb, Drer\dscamb, Drer\kirrela, Drer\il1rapl1b, Drer\lrit3a, Drer\mylk4a, Drer\itgb4, Drer\mylka, Drer\paplna, Drer\robo4, Drer\alpk3b, Drer\lrit3b, Drer\dscaml1, Drer\sdk1b, Drer\ncam1b, Drer\mylk4b, Drer\kirrel3l, Drer\il1rapl2, Drer\dscama, Drer\mylkb, Drer\lrig1, Drer\hmcn1, Drer\igdcc3, Drer\il1rapl1a, Drer\lrig2, Drer\lrit1b, Drer\myom3, Drer\myom1a, Drer\igsf9a, Drer\ncam3, Drer\si:dkey-10h3.1, Drer\kirrel3b, Drer\si:ch1073-459j12.1, Drer\ush2a, Drer\igsf9bb" - "Cele\him-4, Cele\ZC373.4, Cele\unc-89" "Xtro\lrit3, Xtro\lrig3, Xtro\papln, Xtro\mylk4, Xtro\lrig2, Xtro\dscam, Xtro\kirrel2, Xtro\dscaml1, Xtro\lrig1, Xtro\igsf9b, Xtro\mylk3, Xtro\mylk" "Mmus\Mylk3, Mmus\Il1rl2, Mmus\Mylk4, Mmus\Il18rap, Mmus\Lrig1, Mmus\Kirrel2, Mmus\Il1r1, Mmus\Il18r1, Mmus\Lrit1, Mmus\Il1rl1, Mmus\Dscam, Mmus\Dscaml1, Mmus\Mylk2, Mmus\Myom3, Mmus\Lrig3, Mmus\Il1rapl1, Mmus\Sdk1, Mmus\Lrig2, Mmus\Papln, Mmus\Igsf9, Mmus\Il1rap, Mmus\Mylk, Mmus\Il1rapl2, Mmus\Ptprq, Mmus\Kirrel, Mmus\Lrit3, Mmus\Kirrel3, Mmus\Igsf9b, Mmus\Hmcn1" "Hsap\MYLK, Hsap\IL1RL1, Hsap\KIRREL, Hsap\HMCN1, Hsap\LRIG2, Hsap\IL1RAPL1, Hsap\IL1RL2, Hsap\LRIG1, Hsap\IGSF9, Hsap\IL18RAP, Hsap\SDK1, Hsap\IL18R1, Hsap\MYLK2, Hsap\DSCAML1, Hsap\IL1RAP, Hsap\HSPG2, Hsap\MYLK4, Hsap\KIRREL2, Hsap\KIRREL3, Hsap\LRIG3, Hsap\USH2A, Hsap\DSCAM, Hsap\IL1R1, Hsap\LRIT3, Hsap\IGSF9B, Hsap\PAPLN, Hsap\LRIT1, Hsap\MYLK3, Hsap\IL1RAPL2" DRSC22526 I 2.005726148 0.041265334 1.024829205 -0.119416755 -0.580020531 0.332182177 FBgn0026439 Eaat1 Excitatory amino acid transporter 1 http://flybase.org/reports/FBgn0026439 FBgn0025880 protein_coding_gene L-glutamate transmembrane transporter activity ; GO:0005313 | inferred from direct assay glutamate:sodium symporter activity ; GO:0015501 | inferred from direct assay L-aspartate transmembrane transporter activity ; GO:0015183 | inferred from direct assay glutamate:sodium symporter activity ; GO:0015501 | inferred from sequence or structural similarity regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction ; GO:0014853 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype L-glutamate transport ; GO:0015813 | inferred by curator from GO:0005313 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype aspartate transport ; GO:0015810 | inferred by curator from GO:0015183 chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001991 neuromuscular junction ; GO:0031594 | colocalizes_with inferred from direct assay integral component of membrane ; GO:0016021 | inferred by curator from GO:0005313 neuron projection ; GO:0043005 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity terminal bouton ; GO:0043195 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "dEAAT1, EAAT, Dglt-1, AF001784, Dglut-1, CG3747, Eaat1, EAAT1, dEaat1, dEAAT, eaat1" "IPR018107:Sodium:dicarboxylate symporter, conserved site, IPR001991:Sodium:dicarboxylate symporter" CG3747 11-Aug-17 DroID_v2017_08 "Drer\slc1a3a, Drer\slc1a2a, Drer\slc1a6, Drer\slc1a5, Drer\slc1a3b, Drer\slc1a1, Drer\slc1a9, Drer\slc1a4, Drer\slc1a8b, Drer\slc1a2b, Drer\slc1a8a, Drer\slc1a7b, Drer\slc1a7a" - "Cele\glt-7, Cele\glt-5, Cele\glt-4, Cele\glt-3, Cele\glt-1, Cele\glt-6" "Xtro\slc1a4, Xtro\slc1a6, Xtro\slc1a1, Xtro\slc1a2, Xtro\slc1a5, Xtro\slc1a3, Xtro\slc1a7" "Mmus\Slc1a1, Mmus\Slc1a4, Mmus\Slc1a7, Mmus\Slc1a3, Mmus\Slc1a6, Mmus\Slc1a5, Mmus\Slc1a2" "Hsap\SLC1A7, Hsap\SLC1A4, Hsap\SLC1A5, Hsap\SLC1A6, Hsap\SLC1A2, Hsap\SLC1A3, Hsap\SLC1A1" " larval stage | third instar , embryonic stage | stage 15-16 , adult stage , embryonic stage | stage 17 , embryonic stage | stage 16-17 " " larval optic lobe

, ventral nerve cord

, adult head

, midline glial cell

, medulla cortex

, embryonic brain

, interneuron &&of larval brain

, motor neuron &&of ventral nerve cord

, motor neuron

, CNS glial cell | subset

, ventral nerve cord

segmentally repeated " L | third instar neuropil compartment &&of larval central nervous system "locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,neurophysiology defective,touch sensitivity defective,flight defective" "aCC neuron,RP2 motor neuron,neuropil,dopaminergic neuron,synapseEaat1.PR,adult neuromuscular junction,neuromuscular junctionEaat1.PR" FBgn0037518 CG2641 - http://flybase.org/reports/FBgn0037518 protein_coding_gene - - - CG2641 "IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set, IPR011021:Arrestin-like, N-terminal" CG2641 11-Aug-17 DroID_v2017_08 "Drer\txnipb, Drer\arrdc3b, Drer\txnipa, Drer\zgc:110626, Drer\zgc:110353, Drer\arrdc3a, Drer\arrdc1b, Drer\si:ch211-130m23.2, Drer\arrdc1a, Drer\LOC799768, Drer\arrdc2" "Scer\ART5, Scer\ECM21, Scer\ROG3, Scer\LDB19, Scer\ROD1, Scer\ALY2, Scer\CSR2, Scer\ALY1, Scer\RIM8" "Cele\arrd-6, Cele\arrd-14, Cele\arrd-9, Cele\arrd-24, Cele\arrd-13, Cele\arrd-5, Cele\arrd-2, Cele\arrd-25, Cele\rnh-1.2, Cele\arrd-11, Cele\arrd-16, Cele\arrd-23, Cele\arrd-8, Cele\arrd-1, Cele\arrd-27, Cele\arrd-4, Cele\arrd-18, Cele\arrd-3, Cele\arrd-7, Cele\arrd-12, Cele\arrd-19, Cele\arrd-15, Cele\arrd-22" "Xtro\txnip, Xtro\arrdc3, Xtro\arrdc2, Xtro\arrdc4" "Mmus\Txnip, Mmus\Arrdc2, Mmus\Arrdc1, Mmus\Arrdc5, Mmus\Arrdc4, Mmus\Arrdc3" "Hsap\ARRDC2, Hsap\ARRDC5, Hsap\ARRDC1, Hsap\TXNIP, Hsap\ARRDC4, Hsap\ARRDC3" viable FBgn0053816 His1:CG33816 His1:CG33816 http://flybase.org/reports/FBgn0053816 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33816, His1:CG33816" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33816 11-Aug-17 DroID_v2017_08 "Drer\h1f0, Drer\si:dkey-261m9.12, Drer\si:dkey-108k21.10, Drer\h1fx, Drer\si:dkey-108k21.14, Drer\zgc:163061, Drer\zgc:153405, Drer\si:ch1073-159d7.7, Drer\zgc:110425, Drer\si:ch211-113a14.24, Drer\si:dkey-108k21.21, Drer\zgc:110216, Drer\histh1l, Drer\si:ch73-36p18.1, Drer\h1m" Scer\HHO1 "Cele\hil-2, Cele\his-24, Cele\hil-1, Cele\hil-6, Cele\hil-5, Cele\hil-4, Cele\hil-3" - "Mmus\Hist1h1a, Mmus\Hist1h1d, Mmus\H1fx, Mmus\H1foo, Mmus\Hist1h1t, Mmus\H1fnt, Mmus\Hist1h1e, Mmus\Hist1h1b, Mmus\Hist1h1c, Mmus\Hils1" "Hsap\H1F0, Hsap\HIST1H1A, Hsap\HIST1H1C, Hsap\H1FNT, Hsap\HIST1H1D, Hsap\HIST1H1E, Hsap\HIST1H1T, Hsap\H1FOO, Hsap\H1FX, Hsap\HIST1H1B" FBgn0027491 Cdk5alpha Cdk5 activator-like protein http://flybase.org/reports/FBgn0027491 FBgn0026195 protein_coding_gene cyclin-dependent protein kinase 5 activator activity ; GO:0016534 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ; GO:0070059 | inferred from genetic interaction with ninaE adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype inferred from genetic interaction with Cdk5 melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cyclin-dependent protein kinase 5 holoenzyme complex ; GO:0016533 | inferred from physical interaction with Cdk5 axon ; GO:0030424 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "D-p35, p35-21C, p35, P35, Dp35, CG5387, Cdk5a, dCdk5alpha, p35-31C, Cdk5alpha, p25" "IPR004944:Cyclin-dependent kinase 5 activator, IPR013763:Cyclin-like" CG5387 11-Aug-17 DroID_v2017_08 "Drer\cdk5r1a, Drer\si:dkeyp-92c9.2, Drer\cdk5r2a, Drer\cdk5r2b, Drer\cdk5r1b" - Cele\cdka-1 "Xtro\LOC100498128, Xtro\cdk5r2, Xtro\cdk5r1" "Mmus\Cdk5r1, Mmus\Cdk5r2" "Hsap\CDK5R1, Hsap\CDK5R2" "short lived,recessive,neuroanatomy defective,locomotor behavior defective,viable,fertile,lethal,partially lethal - majority die,visible" "eye,segmental nerve branch SNa of A1-7,intersegmental nerve branch ISNb of A1-7,transverse nerve,motor neuron,mesothoracic tergum" FBgn0065032 Arpc3B "Actin-related protein 2/3 complex, subunit 3B" http://flybase.org/reports/FBgn0065032 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with HGNC:706 Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from sequence or structural similarity with HGNC:706 Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with HGNC:706 "CG8936, P21-ARC, BcDNA:SD24339, Arpc3B, Arpc3, Arpc3b" IPR007204:Actin-related protein 2/3 complex subunit 3 CG8936 11-Aug-17 DroID_v2017_08 Drer\arpc3 Scer\ARC18 Cele\arx-5 Xtro\arpc3 Mmus\Arpc3 Hsap\ARPC3 " oogenesis stage , adult stage | female " " nurse cell ring canal

, ovary

" "viable,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053909 His4:CG33909 His4:CG33909 http://flybase.org/reports/FBgn0053909 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33909, His4:CG33909" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33909 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113a14.26, Drer\LOC570405, Drer\zgc:194989, Drer\zgc:163040, Drer\si:dkey-261m9.18, Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.17, Drer\si:dkey-108k21.19, Drer\zgc:154164, Drer\LOC100331412, Drer\si:dkey-261m9.17, Drer\LOC100329358, Drer\LOC794549, Drer\zgc:153409, Drer\si:ch73-368j24.14, Drer\si:ch211-113a14.6, Drer\hist1h4l, Drer\si:ch73-36p18.3, Drer\si:ch73-36p18.4, Drer\si:dkey-108k21.28, Drer\LOC562770, Drer\si:dkey-108k21.12, Drer\LOC100150038, Drer\si:ch73-368j24.1" "Scer\HHF2, Scer\HHF1" "Cele\his-46, Cele\his-31, Cele\his-18, Cele\his-10, Cele\his-14, Cele\his-26, Cele\his-38, Cele\his-5, Cele\his-37, Cele\his-1, Cele\his-64, Cele\his-56, Cele\his-67, Cele\his-60, Cele\his-28, Cele\his-50" "Xtro\hist1h4k, Xtro\LOC100493041, Xtro\hist1h4c" "Mmus\Hist1h4d, Mmus\Hist4h4, Mmus\Hist2h4, Mmus\Hist1h4h, Mmus\Hist1h4n, Mmus\Hist1h4b, Mmus\Hist1h4c, Mmus\Hist1h4f, Mmus\Hist1h4i, Mmus\Hist1h4k, Mmus\Hist1h4j, Mmus\Hist1h4a, Mmus\Hist1h4m" "Hsap\HIST1H4F, Hsap\HIST1H4L, Hsap\HIST1H4E, Hsap\HIST2H4A, Hsap\HIST2H4B, Hsap\HIST1H4H, Hsap\HIST1H4I, Hsap\HIST1H4K, Hsap\HIST1H4D, Hsap\HIST1H4J, Hsap\HIST1H4B, Hsap\HIST1H4A, Hsap\HIST4H4, Hsap\HIST1H4G, Hsap\HIST1H4C" FBgn0053874 His2B:CG33874 His2B:CG33874 http://flybase.org/reports/FBgn0053874 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33874, His2B:CG33874" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33874 11-Aug-17 DroID_v2017_08 "Drer\LOC100329560, Drer\zgc:114046, Drer\si:dkey-108k21.27, Drer\si:dkey-23a13.16, Drer\hist2h2l, Drer\zgc:194989, Drer\si:dkey-261m9.19, Drer\si:ch211-113a14.28, Drer\LOC100329290, Drer\si:dkey-23a13.22, Drer\si:ch211-113a14.29, Drer\si:ch73-36p18.3, Drer\hist1h2ba, Drer\si:ch1073-159d7.13, Drer\LOC100334869, Drer\si:dkey-108k21.11, Drer\si:dkey-23a13.1, Drer\zgc:173587, Drer\si:dkey-261m9.6, Drer\si:ch211-113a14.11, Drer\ano9a, Drer\LOC100334559, Drer\zgc:92591, Drer\si:ch73-368j24.8, Drer\si:ch1073-159d7.5" "Scer\HTB1, Scer\HTB2" "Cele\his-29, Cele\his-58, Cele\his-22, Cele\his-39, Cele\his-11, Cele\his-66, Cele\his-52, Cele\his-8, Cele\his-15, Cele\his-41, Cele\his-34, Cele\his-62, Cele\his-20, Cele\his-54, Cele\his-44, Cele\his-4, Cele\his-48" "Xtro\LOC100492632, Xtro\LOC101733489, Xtro\LOC101735218, Xtro\LOC100486150, Xtro\LOC101734494, Xtro\LOC100497082, Xtro\LOC100496181, Xtro\LOC100495396, Xtro\LOC101733171, Xtro\LOC100498647, Xtro\LOC100496436, Xtro\LOC100495578, Xtro\LOC100498553, Xtro\hist1h2bm, Xtro\LOC101731959, Xtro\LOC100497915, Xtro\LOC100487485, Xtro\LOC100495041, Xtro\LOC101734862, Xtro\LOC100496445, Xtro\LOC101733828, Xtro\LOC100486870, Xtro\LOC101731852, Xtro\LOC101730940, Xtro\LOC100485294, Xtro\LOC100485134, Xtro\hist2h2be, Xtro\hist1h2bk, Xtro\LOC101735164, Xtro\LOC100495415, Xtro\LOC100498072, Xtro\LOC100498329, Xtro\LOC101731067, Xtro\hist1h2bj" "Mmus\Hist3h2ba, Mmus\Hist1h2be, Mmus\Hist2h2bb, Mmus\Hist1h2bf, Mmus\Hist1h2bj, Mmus\Hist1h2bg, Mmus\1700024P04Rik, Mmus\Hist1h2bb, Mmus\Hist1h2bq, Mmus\Hist1h2bp, Mmus\Hist1h2bc, Mmus\Hist1h2br, Mmus\Hist1h2bh, Mmus\Hist2h2be, Mmus\Hist1h2bk, Mmus\H2bfm, Mmus\Hist1h2bl, Mmus\Hist1h2bm, Mmus\Hist1h2bn, Mmus\Hist1h2ba" "Hsap\HIST1H2BE, Hsap\HIST1H2BF, Hsap\HIST1H2BK, Hsap\HIST1H2BC, Hsap\HIST1H2BL, Hsap\HIST1H2BG, Hsap\HIST1H2BA, Hsap\HIST1H2BM, Hsap\HIST2H2BE, Hsap\HIST1H2BB, Hsap\H2BFWT, Hsap\HIST1H2BI, Hsap\HIST1H2BJ, Hsap\HIST3H2BB, Hsap\HIST1H2BO, Hsap\HIST1H2BH, Hsap\HIST1H2BD, Hsap\H2BFM, Hsap\HIST2H2BF, Hsap\HIST1H2BN" FBgn0034733 CG4752 - http://flybase.org/reports/FBgn0034733 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR002821 - - CG4752 "IPR002821:Hydantoinase/oxoprolinase, IPR003692:Hydantoinase B/oxoprolinase, IPR008040:Hydantoinaseoxoprolinase, N-terminal" CG4752 11-Aug-17 DroID_v2017_08 Drer\oplah Scer\OXP1 Cele\Y38F2AR.12 Xtro\oplah Mmus\Oplah Hsap\OPLAH "viable,fertile" DRSC04486 I 1.357837881 2.622022862 0.351124353 0.994816415 -0.361937741 0.584638702 FBgn0032536 Ance-3 Ance-3 http://flybase.org/reports/FBgn0032536 protein_coding_gene peptidyl-dipeptidase activity ; GO:0008241 | inferred from electronic annotation with InterPro:IPR001548 metallopeptidase activity ; GO:0008237 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001548 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001548 integral component of membrane ; GO:0016021 | inferred from sequence model "CG17988, CT40163, BG:DS00180.5, DS00180.5, CG31766, CG31843, Ance-3, ance-3" "IPR001548:Peptidase M2, peptidyl-dipeptidase A" CG17988 11-Aug-17 DroID_v2017_08 "Drer\ace, Drer\si:dkey-194e6.1, Drer\ace2" - Cele\acn-1 "Xtro\ace2, Xtro\ace, Xtro\tmem27" "Mmus\Ace3, Mmus\Ace, Mmus\Ace2, Mmus\Tmem27" "Hsap\ACE, Hsap\TMEM27, Hsap\ACE2" viable DRSC02649 K -1.196561988 -0.171456922 0.267623732 -0.251603748 0.569999257 1.580791178 FBgn0003356 Jon99Cii Jonah 99Cii http://flybase.org/reports/FBgn0003356 "FBgn0001288, FBgn0011833, FBgn0051034" protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from sequence model proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "Ser99Da, CG31034, 99Calpha, Jon99Cbeta, Jon99Calpha, Jon99Cbetaii, Jon99Calphai, SP122, SER1, Ser5, Ser1, Serl, Jon99C1, Jon99C2, Jon99C, CG7877, JonC, Jon99B, Jon99Cii" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG31034 11-Aug-17 DroID_v2017_08 "Drer\zgc:112368, Drer\habp2, Drer\si:dkey-78l4.10, Drer\zgc:92041, Drer\zgc:112285, Drer\zgc:163025, Drer\zgc:112302, Drer\zgc:92745, Drer\prss59.1, Drer\prss59.2, Drer\ela3l" - - - "Mmus\Cela3a, Mmus\F9, Mmus\C1s2, Mmus\Cela1, Mmus\Ctrc, Mmus\Cela3b, Mmus\Ctrl, Mmus\Habp2, Mmus\C1s1, Mmus\Ctrb1, Mmus\Cela2a" "Hsap\HABP2, Hsap\C1S, Hsap\PROC" FBgn0002707 mei-9 meiotic 9 http://flybase.org/reports/FBgn0002707 - protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Ercc1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VS48 damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000015911 single-stranded DNA endodeoxyribonuclease activity ; GO:0000014 | inferred from biological aspect of ancestor with PANTHER:PTN000015911 protein binding ; GO:0005515 | inferred from physical interaction with mus312 inferred from physical interaction with Ercc1 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000015911 protein binding ; GO:0005515 | inferred from physical interaction with hdm "nucleotide-excision repair ; GO:0006289 | inferred from mutant phenotype nucleotide-excision repair ; GO:0006289 | traceable author statement reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype nucleotide-excision repair involved in interstrand cross-link repair ; GO:1901255 | inferred from biological aspect of ancestor with PANTHER:PTN000015911 mismatch repair ; GO:0006298 | inferred from mutant phenotype DNA recombination ; GO:0006310 | traceable author statement resolution of meiotic recombination intermediates ; GO:0000712 | traceable author statement female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype meiotic chromosome segregation ; GO:0045132 | inferred from mutant phenotype resolution of meiotic recombination intermediates ; GO:0000712 | inferred from mutant phenotype nucleotide-excision repair, DNA incision, 5'-to lesion ; GO:0006296 | inferred from biological aspect of ancestor with PANTHER:PTN000015911 double-strand break repair via homologous recombination ; GO:0000724 | inferred from biological aspect of ancestor with PANTHER:PTN000015911 oocyte fate determination ; GO:0030716 | inferred from mutant phenotype double-strand break repair ; GO:0006302 | traceable author statement cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with mus81 nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity" protein complex ; GO:0043234 | inferred from direct assay nucleotide-excision repair factor 1 complex ; GO:0000110 | inferred from biological aspect of ancestor with PANTHER:PTN000015911 "xpf/mei-9, mei9, MEI-9, DhR1, DmXPF, mus(1)110, mus110, CG3697, mei-9, Rad1p, Mei-9" "IPR006166:ERCC4 domain, IPR006167:DNA repair protein XPF, IPR011335:Restriction endonuclease type II-like, IPR010994:RuvA domain 2-like" CG3697 11-Aug-17 DroID_v2017_08 Drer\ercc4 Scer\RAD1 Cele\xpf-1 Xtro\ercc4 "Mmus\Fancm, Mmus\Ercc4" "Hsap\FANCM, Hsap\ERCC4" "radiation sensitive,chemical sensitive,viable,fertile,meiotic cell cycle defective,female,female sterile,wild-type,mitotic cell cycle defective,recessive,DNA repair defective,female fertile,lethal,partially,short lived,increased cell death,conditional" "presumptive oocyte,mitosis & nuclear chromosome,egg chamber,eye,conditional" FBgn0267383 Ubc87F Ubiquitin conjugating enzyme 87F http://flybase.org/reports/FBgn0267383 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12482 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000629793 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000629793 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12482 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "CG9602, Ubc87F, AT76, 83A, UBC, Ubc87Fb, BcDNA:GH25305" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG9602 11-Aug-17 DroID_v2017_08 "Drer\ube2g1b, Drer\cdc34a, Drer\ube2g2, Drer\ube2r2, Drer\ube2g1a, Drer\cdc34b" "Scer\CDC34, Scer\UBC7" "Cele\ubc-7, Cele\ubc-14" "Xtro\cdc34, Xtro\ube2r2, Xtro\ube2g1, Xtro\ube2g2" "Mmus\Ube2r2, Mmus\Ube2g2, Mmus\Cdc34, Mmus\Ube2g1" "Hsap\UBE2G2, Hsap\CDC34, Hsap\UBE2G1, Hsap\UBE2R2" FBgn0032076 CG9510 - http://flybase.org/reports/FBgn0032076 protein_coding_gene argininosuccinate lyase activity ; GO:0004056 | inferred from biological aspect of ancestor with PANTHER:PTN000154674 arginine biosynthetic process via ornithine ; GO:0042450 | inferred from biological aspect of ancestor with PANTHER:PTN000154674 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000154674 "gh06087, CG33085, BEST:GH06087, CG9510" "IPR000362:Fumarate lyase family, IPR008948:L-Aspartase-like, IPR009049:Argininosuccinate lyase, IPR024083:Fumarase/histidase, N-terminal, IPR020557:Fumarate lyase, conserved site, IPR029419:Argininosuccinate lyase, C-terminal, IPR022761:Fumarate lyase, N-terminal" CG9510 11-Aug-17 DroID_v2017_08 Drer\asl Scer\ARG4 - Xtro\asl Mmus\Asl "Hsap\ASL, Hsap\CRCP" "viable,fertile" FBgn0015039 Cyp9b2 Cytochrome P450-9b2 http://flybase.org/reports/FBgn0015039 FBgn0043831 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403, InterPro:IPR017972" - "cyp9b2, 9b2, P450, P-450, BEST:GH08116, CG4486, Cyp9b2, P-450 Cyp9b2" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV, IPR017972:Cytochrome P450, conserved site" CG4486 11-Aug-17 DroID_v2017_08 "Drer\cyp3c4, Drer\cyp4t8, Drer\cyp3c3, Drer\tbxas1, Drer\cyp4f3, Drer\cyp4v7, Drer\cyp4v8, Drer\cyp3a65, Drer\cyp3c2, Drer\cyp3c1" Scer\ERG11 "Cele\cyp-25A6, Cele\cyp-29A3, Cele\cyp-25A2, Cele\cyp-13A4, Cele\cyp-13A10, Cele\cyp-13B2, Cele\cyp-13A1, Cele\cyp-25A1, Cele\cyp-13A2, Cele\cyp-31A2, Cele\cyp-33E2, Cele\cyp-32A1, Cele\cyp-13B1, Cele\cyp-13A11, Cele\cyp-25A4, Cele\cyp-13A5, Cele\cyp-33C3, Cele\cyp-13A3, Cele\cyp-42A1, Cele\cyp-43A1, Cele\cyp-44A1, Cele\cyp-32B1, Cele\cyp-31A3, Cele\cyp-29A4, Cele\cyp-13A12, Cele\cyp-37B1, Cele\cyp-25A3, Cele\cyp-13A7, Cele\cyp-13A8, Cele\cyp-13A6, Cele\cyp-29A2" "Xtro\cyp3a5, Xtro\LOC100494419, Xtro\tbxas1, Xtro\cyp3a4" "Mmus\Cyp4a12a, Mmus\Cyp3a57, Mmus\Cyp4f16, Mmus\Cyp4a31, Mmus\Cyp3a11, Mmus\Cyp4f39, Mmus\Cyp3a16, Mmus\Cyp3a41b, Mmus\Cyp3a59, Mmus\Cyp3a13, Mmus\Cyp4a10, Mmus\Cyp4f13, Mmus\Cyp4a14, Mmus\Cyp3a41a, Mmus\Cyp4a32, Mmus\Cyp3a44, Mmus\Cyp4f15, Mmus\Tbxas1, Mmus\Cyp4f14, Mmus\Cyp4v3, Mmus\Cyp4a12b, Mmus\Cyp7a1, Mmus\Cyp4b1, Mmus\Cyp3a25, Mmus\Cyp4f37, Mmus\Cyp4f18" "Hsap\CYP4B1, Hsap\CYP7A1, Hsap\CYP4Z1, Hsap\CYP4X1, Hsap\CYP3A4, Hsap\CYP4F8, Hsap\CYP4F3, Hsap\CYP3A5, Hsap\CYP4F12, Hsap\CYP4F11, Hsap\CYP3A7, Hsap\CYP4A22, Hsap\CYP4F2, Hsap\CYP4V2, Hsap\TBXAS1, Hsap\CYP4F22, Hsap\CYP4A11, Hsap\CYP3A43, Hsap\CYP3A7-CYP3A51P" FBgn0015774 NetB Netrin-B http://flybase.org/reports/FBgn0015774 - protein_coding_gene - salivary gland boundary specification ; GO:0007432 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from genetic interaction with NetA glial cell migration ; GO:0008347 | inferred from mutant phenotype synaptic target attraction ; GO:0016200 | traceable author statement axon guidance ; GO:0007411 | inferred from sequence or structural similarity motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype regulation of photoreceptor cell axon guidance ; GO:2000289 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with NetA inferred from genetic interaction with unc-5 synaptic target recognition ; GO:0008039 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity "netB, CT29512, CG10521, NetB, netrin B, netrin, net, NETB" "IPR018933:Netrin module, non-TIMP type, IPR001134:Netrin domain, IPR002049:Laminin EGF domain, IPR008211:Laminin, N-terminal, IPR008993:Tissue inhibitor of metalloproteinases-like, OB-fold, IPR008979:Galactose-binding domain-like" CG10521 11-Aug-17 DroID_v2017_08 "Drer\ntn2, Drer\ntn5, Drer\si:ch211-241e1.3, Drer\egflam, Drer\ntn1b, Drer\ntn1a, Drer\ntng2a, Drer\ntng1a, Drer\lama3, Drer\lamc3, Drer\lama1, Drer\si:dkey-220k22.1, Drer\lamc1, Drer\si:ch211-158d24.2, Drer\lama4, Drer\si:dkey-202e22.2, Drer\ush2a, Drer\lama5, Drer\LOC567928" - "Cele\unc-6, Cele\lam-3" "Xtro\lama3, Xtro\lama4, Xtro\ntng2, Xtro\lamc2, Xtro\lama5, Xtro\ntn1, Xtro\ntn3, Xtro\lama1, Xtro\lama2, Xtro\lamc1, Xtro\ntng1" "Mmus\Egflam, Mmus\Lamc1, Mmus\Tbc1d24, Mmus\Lama2, Mmus\Ntn3, Mmus\Lama1, Mmus\Ntng2, Mmus\Megf9, Mmus\Lamc3, Mmus\Ntn5, Mmus\Lamc2, Mmus\Ntng1, Mmus\Ush2a, Mmus\Lama4, Mmus\Lama3, Mmus\Lama5, Mmus\Ntn1, Mmus\Ntn4" "Hsap\NTN5, Hsap\NTNG2, Hsap\EGFLAM, Hsap\LAMA4, Hsap\LAMC1, Hsap\NTN1, Hsap\LAMC3, Hsap\NTN3, Hsap\LAMA5, Hsap\USH2A, Hsap\LAMC2, Hsap\NTN4, Hsap\NTNG1, Hsap\LAMA1, Hsap\LAMA2, Hsap\MEGF9, Hsap\LAMA3" " embryonic stage , embryonic stage | stage 12-14 , embryonic stage | stage 13,14 , embryonic stage | stage 14 , embryonic stage | stage 12-17 , embryonic stage | early , embryonic stage | stage 13-17 , embryonic stage -- adult stage " " embryonic brain | restricted

, midline glial cell

, dorsal mesothoracic disc | precursor

, abdominal 2--7 dorsal acute muscle 2

, visceral mesoderm

, somatic mesoderm | restricted

, mesectoderm

, mesoderm anlage

, MP1 neuron

, abdominal 2--7 ventral longitudinal muscle 3

, abdominal 2--7 ventral longitudinal muscle 4

, neuroblast MP2

, embryonic nervous system | restricted

" " embryonic stage | stage 12-17 , embryonic stage | stage >=14 , embryonic stage , embryonic stage | stage >=12 , embryonic stage | stage 14 , embryonic stage | stage 13 " " neuron &&of embryonic nervous system

, central nervous system | restricted

, embryonic peripheral nervous system | restricted

, visceral mesoderm

, larval muscle system | restricted

, imaginal disc primordium

, embryonic/larval dorsal vessel

, eye-antennal disc primordium

, labial disc primordium

, mesectoderm

, mesoderm

, somatic mesoderm

, dorsal mesothoracic disc primordium

, chordotonal organ

, genital disc primordium

, midline glial cell

, dorsal metathoracic disc primordium

, stomatogastric nervous system

" "viable,neuroanatomy defective,visible,partially lethal - majority die,wild-type,decreased cell death,female semi-fertile" "peripheral glial cell,optic lobe,photoreceptor cell R8 stalk,intersegmental nerve branch ISNb of A1-7,wing,motor neuron | third instar larval stage,somatic clone,transverse nerve,segmental nerve,optic nerve,photoreceptor cell & axonGMR.PF,photoreceptor cell & axon,lamina,pCC neuron & axonunspecified,longitudinal connective,commissure,axon-537.4,intersegmental nerve,abdominal segmental nerve,presumptive embryonic salivary gland,axonelav.PLu, -537.4" FBgn0000565 Eip71CD Ecdysone-induced protein 28/29kD http://flybase.org/reports/FBgn0000565 FBgn0026825 protein_coding_gene peptide-methionine (S)-S-oxide reductase activity ; GO:0008113 | inferred from direct assay oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002569 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype sulfur amino acid metabolic process ; GO:0000096 | non-traceable author statement cellular response to oxidative stress ; GO:0034599 | inferred from expression pattern neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern response to oxidative stress ; GO:0006979 | inferred from mutant phenotype - "Eip71C, MsrA, Eip28/29, eip28/29, Eip28 /29, DROZ60MEX, Eip28, CG7266, Eip71CD, dmsrA" IPR002569:Peptide methionine sulphoxide reductase MsrA CG7266 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-358c10.1, Drer\msra" Scer\MXR1 Cele\msra-1 "Xtro\msra.1, Xtro\msra.2" Mmus\Msra Hsap\MSRA " larval stage | third instar , adult stage , larval stage , adult stage && oogenesis stage " " embryonic/larval salivary gland

, adult midgut

, embryonic/larval fat body

, Malpighian tubule

, embryonic/larval hemocyte

, adult fat body

, nurse cell

, embryonic/larval anterior spiracle

, central nervous system

, embryonic/larval midgut

, lymph gland

, oocyte

, epidermis

, embryonic/larval pharynx

, embryonic/larval proventriculus | posterior

, crop

" "increased cell number,size defective,oxidative stress response defective,long lived,RU486 conditional,viable,fertile" eye FBgn0016693 Past1 Putative Achaete Scute Target 1 http://flybase.org/reports/FBgn0016693 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR030381 endocytic recycling ; GO:0032456 | inferred from electronic annotation with InterPro:IPR029952 endocytosis ; GO:0006897 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from genetic interaction with H oogenesis ; GO:0048477 | inferred from mutant phenotype subsynaptic reticulum organization ; GO:1990255 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from genetic interaction with N subsynaptic reticulum ; GO:0071212 | inferred from direct assay "Past1, dEHD, PAST, Ehd, PAST-1, CG6148, Past-1, CG66148, dEHD1, PAST1" "IPR030381:Dynamin-type guanine nucleotide-binding (G) domain, IPR018247:EF-Hand 1, calcium-binding site, IPR000261:EH domain, IPR011992:EF-hand domain pair, IPR022812:Dynamin superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR002048:EF-hand domain, IPR029952:EH domain-containing protein 4, IPR031692:EH domain-containing protein, N-terminal" CG6148 11-Aug-17 DroID_v2017_08 "Drer\ehd2a, Drer\ehd1a, Drer\ehd3, Drer\srl, Drer\ehd2b, Drer\ehd1b, Drer\ehd4" "Scer\EDE1, Scer\END3" Cele\rme-1 "Xtro\ehd4, Xtro\ehd1, Xtro\srl, Xtro\ehd3, Xtro\ehd2" "Mmus\Srl, Mmus\Ehd4, Mmus\Ehd2, Mmus\Ehd1, Mmus\Ehd3" "Hsap\EHD3, Hsap\EHD2, Hsap\SRL, Hsap\EHD1, Hsap\EHD4" "viable,developmental rate defective,short lived,partially lethal - majority die,heat sensitive,semi-sterile" "testis,spermatid cyst,individualization stage spermatid,cystic bulge,ovary,oocyte,egg chamber,embryonic/larval garland cell" FBgn0037770 Art4 Arginine methyltransferase 4 http://flybase.org/reports/FBgn0037770 protein_coding_gene histone methyltransferase activity ; GO:0042054 | inferred from direct assay histone-arginine N-methyltransferase activity ; GO:0008469 | inferred from sequence or structural similarity with MGI:MGI:1913208 protein-arginine omega-N asymmetric methyltransferase activity ; GO:0035242 | inferred from direct assay protein-arginine omega-N monomethyltransferase activity ; GO:0035241 | inferred from direct assay "peptidyl-arginine methylation, to asymmetrical-dimethyl arginine ; GO:0019919 | inferred from direct assay histone methylation ; GO:0016571 | inferred from direct assay histone arginine methylation ; GO:0034969 | inferred from sequence or structural similarity with UniProtKB:Q9WVG6" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay histone methyltransferase complex ; GO:0035097 | inferred from direct assay "DART4, CG5358, Art4, CARM1, dArt 4, Dart4" "IPR025799:Protein arginine N-methyltransferase, IPR011993:PH domain-like, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG5358 11-Aug-17 DroID_v2017_08 "Drer\carm1l, Drer\carm1" Scer\HMT1 - Xtro\carm1 Mmus\Carm1 Hsap\CARM1 "cell death defective,increased cell death,conditional,viable,fertile" FBgn0039254 Nmnat Nicotinamide mononucleotide adenylyltransferase http://flybase.org/reports/FBgn0039254 protein_coding_gene nicotinate-nucleotide adenylyltransferase activity ; GO:0004515 | inferred from biological aspect of ancestor with PANTHER:PTN000247701 nicotinamide-nucleotide adenylyltransferase activity ; GO:0000309 | inferred from direct assay unfolded protein binding ; GO:0051082 | inferred from direct assay photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype dendritic spine maintenance ; GO:0097062 | inferred from mutant phenotype 'de novo' NAD biosynthetic process from aspartate ; GO:0034628 | inferred from biological aspect of ancestor with PANTHER:PTN000247701 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "dNmnat, NmnatB, AAL90149, CG13645, nmnat, Nmnat, NMNAT, 3R4, DmNMNAT, Nmnat1, DmNmnat" "IPR005248:Nicotinate/nicotinamide nucleotide adenylyltransferase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR004821:Cytidyltransferase-like domain" CG13645 11-Aug-17 DroID_v2017_08 "Drer\nmnat1-rbp7a, Drer\si:ch73-170l17.1, Drer\nmnat2, Drer\nmnat1" "Scer\NMA1, Scer\NMA2" "Cele\nmat-1, Cele\nmat-2" "Xtro\nmnat1, Xtro\nmnat2" "Mmus\Nmnat3, Mmus\Nmnat2, Mmus\Nmnat1" "Hsap\NMNAT2, Hsap\NMNAT1, Hsap\NMNAT3" "neuroanatomy defective,viable,somatic clone,phototaxis defective,neurophysiology defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage" "adult olfactory receptor neuron,alpha/beta Kenyon cell,somatic clone,optic cartridge,t-bar,eye,rhabdomere,ommatidium,dorsal multidendritic neuron ddaC,dendrite | somatic clone,dendrite,class III dendritic arborizing neuron,class I dendritic arborizing neuron,motor neuron,alpha/beta Kenyon cell | adult stage" FBgn0001223 Hsp22 Heat shock protein 22 http://flybase.org/reports/FBgn0001223 "FBgn0044743, FBgn0052041, FBgn0061943, FBtr0076448, FBpp0076176, FBtr0076449, FBpp0076177, FBtr0076450, FBpp0076178, FBtr0076451, FBpp0076179" protein_coding_gene identical protein binding ; GO:0042802 | inferred from physical interaction with Hsp22 unfolded protein binding ; GO:0051082 | inferred from sequence model unfolded protein binding ; GO:0051082 | inferred from direct assay response to heat ; GO:0009408 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay response to heat ; GO:0009408 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype mitochondrial matrix ; GO:0005759 | inferred from direct assay "Dmel20.8, Hsp22, hsp22, EP(3)3247, DmHsp22, 22, CG32041, CG4460, anon-WO0140519.138, anon-WO0118547.50, small hsp locus 67B, HSP22" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4460 11-Aug-17 DroID_v2017_08 "Drer\hspb1, Drer\hspb11, Drer\hspb15, Drer\si:dkey-1k23.3, Drer\hspb12, Drer\cryaa, Drer\hspb3, Drer\hspb8, Drer\hspb7, Drer\cryaba, Drer\hspb9, Drer\hspb6, Drer\hspb2" Scer\HSP26 "Cele\hsp-16.41, Cele\hsp-16.2, Cele\hsp-12.6, Cele\hsp-17, Cele\hsp-43, Cele\hsp-16.1, Cele\hsp-12.3, Cele\Y55F3BR.6, Cele\hsp-16.11, Cele\sip-1, Cele\ZK1128.7, Cele\hsp-12.2, Cele\hsp-12.1, Cele\hsp-16.48, Cele\F08H9.4, Cele\F08H9.3, Cele\hsp-16.49" "Xtro\cryaa, Xtro\hspb8, Xtro\uqcrh, Xtro\hsp30e, Xtro\hspb1, Xtro\hspb6, Xtro\hsp30d, Xtro\hspb3, Xtro\hspb2, Xtro\cryab" "Mmus\Cryaa, Mmus\Hspb7, Mmus\Hspb1, Mmus\Cryab, Mmus\Hspb2, Mmus\Hspb6, Mmus\Hspb3, Mmus\Hspb8, Mmus\Hspb9" "Hsap\HSPB2, Hsap\CRYAB, Hsap\LOC102724652, Hsap\HSPB6, Hsap\HSPB8, Hsap\HSPB7, Hsap\HSPB9, Hsap\HSPB3, Hsap\HSPB1, Hsap\CRYAA" prepupal stage "cold stress response defective,viable,fertile,long lived,short lived,locomotor behavior defective,oxidative stress response defective,tetracycline conditional,heat stress response defective" FBgn0053878 His2B:CG33878 His2B:CG33878 http://flybase.org/reports/FBgn0053878 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33878, His2B:CG33878" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33878 11-Aug-17 DroID_v2017_08 "Drer\LOC100334559, Drer\si:dkey-23a13.16, Drer\si:ch1073-153i20.3, Drer\si:dkey-23a13.5, Drer\zgc:173587, Drer\LOC100329560, Drer\si:dkey-23a13.1, Drer\ano9a, Drer\si:dkey-261m9.19, Drer\si:ch73-36p18.3, Drer\zgc:194989, Drer\zgc:173585, Drer\si:ch211-113a14.11, Drer\LOC100329290, Drer\hist2h2l, Drer\si:ch211-113a14.29, Drer\si:ch1073-159d7.5, Drer\si:ch73-368j24.8, Drer\si:dkey-261m9.6, Drer\si:dkey-108k21.11, Drer\si:ch1073-159d7.13, Drer\si:dkey-108k21.27, Drer\LOC100334869, Drer\zgc:114046, Drer\hist1h2ba, Drer\si:ch211-113a14.28, Drer\zgc:92591" "Scer\HTB2, Scer\HTB1" "Cele\his-20, Cele\his-54, Cele\his-58, Cele\his-34, Cele\his-62, Cele\his-66, Cele\his-11, Cele\his-52, Cele\his-41, Cele\his-4, Cele\his-22, Cele\his-15, Cele\his-29, Cele\his-39, Cele\his-44, Cele\his-8, Cele\his-48" "Xtro\LOC100495041, Xtro\LOC100486870, Xtro\LOC100495396, Xtro\LOC100497082, Xtro\LOC101734494, Xtro\LOC100495415, Xtro\LOC100498647, Xtro\LOC100498553, Xtro\LOC101733489, Xtro\LOC100496445, Xtro\LOC100498329, Xtro\hist1h2bj, Xtro\LOC100492632, Xtro\hist1h2bk, Xtro\LOC100485294, Xtro\LOC101730940, Xtro\LOC100497915, Xtro\LOC101735218, Xtro\hist2h2be, Xtro\LOC101731852, Xtro\LOC100498072, Xtro\LOC100486150, Xtro\LOC100487485, Xtro\LOC100496181, Xtro\LOC101733171, Xtro\LOC101733828, Xtro\LOC101731959, Xtro\LOC100496436, Xtro\LOC101731067, Xtro\hist1h2bm, Xtro\LOC100495578, Xtro\LOC100485134, Xtro\LOC101734862, Xtro\LOC101735164" "Mmus\Hist1h2bf, Mmus\Hist1h2bb, Mmus\Hist1h2ba, Mmus\Hist1h2bn, Mmus\Hist2h2be, Mmus\1700024P04Rik, Mmus\Hist3h2ba, Mmus\H2bfm, Mmus\Hist1h2bm, Mmus\Hist1h2bl, Mmus\Hist1h2bc, Mmus\Hist1h2bh, Mmus\Hist1h2bg, Mmus\Hist1h2be, Mmus\Hist1h2bj, Mmus\Hist1h2bk, Mmus\Hist1h2br, Mmus\Hist1h2bp, Mmus\Hist2h2bb, Mmus\Hist1h2bq" "Hsap\HIST1H2BK, Hsap\H2BFWT, Hsap\HIST2H2BF, Hsap\HIST1H2BJ, Hsap\HIST1H2BN, Hsap\HIST1H2BC, Hsap\HIST1H2BH, Hsap\HIST1H2BM, Hsap\HIST1H2BO, Hsap\HIST3H2BB, Hsap\HIST2H2BE, Hsap\HIST1H2BL, Hsap\HIST1H2BB, Hsap\H2BFM, Hsap\HIST1H2BD, Hsap\HIST1H2BA, Hsap\HIST1H2BG, Hsap\HIST1H2BE, Hsap\HIST1H2BF, Hsap\HIST1H2BI" FBgn0053812 His3:CG33812 His3:CG33812 http://flybase.org/reports/FBgn0053812 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33812, His3:CG33812" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33812 11-Aug-17 DroID_v2017_08 "Drer\hist2h3c, Drer\h3f3b.1, Drer\cenpa, Drer\zgc:113984, Drer\h3f3c, Drer\hist2h3ca1, Drer\LOC108190747, Drer\si:ch1073-429i10.3, Drer\zgc:113983, Drer\zgc:173552, Drer\si:ch73-36p18.2, Drer\h3f3d, Drer\h3f3a, Drer\LOC108190746" "Scer\HHT2, Scer\CSE4, Scer\HHT1" "Cele\his-27, Cele\his-49, Cele\his-9, Cele\his-6, Cele\his-63, Cele\his-69, Cele\his-55, Cele\his-71, Cele\his-72, Cele\his-25, Cele\his-45, Cele\his-32, Cele\his-59, Cele\his-74, Cele\his-17, Cele\his-42, Cele\his-13, Cele\his-2" "Xtro\cenpa, Xtro\hist2h3d, Xtro\h3f3b" "Mmus\H3f3a, Mmus\H3f3b, Mmus\Hist1h3a, Mmus\Hist1h3g, Mmus\Hist1h3e, Mmus\Hist1h3c, Mmus\Hist2h3c1, Mmus\Hist1h3i, Mmus\Hist1h3f, Mmus\Cenpa, Mmus\Hist1h3b, Mmus\Hist1h3h, Mmus\Hist2h3b, Mmus\Hist1h3d, Mmus\Hist2h3c2" "Hsap\H3F3A, Hsap\HIST1H3B, Hsap\H3F3B, Hsap\CENPA, Hsap\HIST1H3J, Hsap\HIST2H3D, Hsap\HIST2H3C, Hsap\HIST1H3I, Hsap\HIST1H3E, Hsap\HIST1H3A, Hsap\HIST1H3H, Hsap\HIST3H3, Hsap\HIST2H3A, Hsap\HIST1H3F, Hsap\HIST1H3C, Hsap\HIST1H3G, Hsap\HIST1H3D, Hsap\H3F3C" FBgn0039371 CG4960 - http://flybase.org/reports/FBgn0039371 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of intracellular transport ; GO:0032386 | inferred from sequence or structural similarity with MGI:MGI:1917585 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with MGI:MGI:1917585 "BcDNA:AT31258, CG4960" IPR004345:TB2/DP1/HVA22-related protein CG4960 11-Aug-17 DroID_v2017_08 "Drer\reep3a, Drer\reep3b, Drer\reep6, Drer\reep5, Drer\zgc:101744, Drer\reep2, Drer\reep1" Scer\YOP1 "Cele\T03F6.6, Cele\F56B3.6, Cele\yop-1, Cele\Y110A2AR.1" "Xtro\reep4, Xtro\reep6, Xtro\reep5, Xtro\reep3" "Mmus\Reep5, Mmus\Reep4, Mmus\Reep3, Mmus\Reep1, Mmus\Reep2, Mmus\Reep6" "Hsap\REEP6, Hsap\REEP2, Hsap\REEP1, Hsap\REEP5, Hsap\REEP3" viable DRSC27774 EK -1.026019985 -0.127231246 1.766484873 0.662442011 1.692223132 1.442477815 FBgn0015831 Rtnl2 Rtnl2 http://flybase.org/reports/FBgn0015831 FBgn0046598 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "trop, Tml84D, CG1279, anon-WO0170980.134, Rtnl2, rtnl2" IPR003388:Reticulon CG1279 11-Aug-17 DroID_v2017_08 "Drer\rtn3, Drer\rtn4a, Drer\rtn1b, Drer\rtn2b, Drer\rtn4b, Drer\rtn2a, Drer\rtn1a" "Scer\RTN1, Scer\RTN2" Cele\ret-1 "Xtro\rtn1, Xtro\rtn3, Xtro\rtn4, Xtro\rtn2" "Mmus\Rtn1, Mmus\Rtn2, Mmus\Rtn3, Mmus\Rtn4" "Hsap\RTN4, Hsap\RTN3, Hsap\RTN1, Hsap\RTN2" viable FBgn0035669 CG6592 - http://flybase.org/reports/FBgn0035669 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP105, CG6592, lincRNA.S4213" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG6592 11-Aug-17 DroID_v2017_08 "Drer\mst1, Drer\ela3l, Drer\zgc:112368, Drer\zgc:112285, Drer\habp2, Drer\zgc:163025, Drer\plg, Drer\zgc:92745, Drer\plaua, Drer\zgc:92041, Drer\zgc:112302, Drer\f9b, Drer\f7, Drer\f10, Drer\f2" - "Cele\svh-1, Cele\try-3" "Xtro\f2, Xtro\f10, Xtro\habp2, Xtro\plat, Xtro\mst1, Xtro\proc, Xtro\st14, Xtro\prss12" "Mmus\Plg, Mmus\Hgfac, Mmus\Plat, Mmus\Hp, Mmus\Plau, Mmus\Cela1, Mmus\Ctrl, Mmus\Habp2, Mmus\St14, Mmus\Prss12, Mmus\Cela3b, Mmus\Ctrb1, Mmus\Cela2a, Mmus\F7, Mmus\Ctrc, Mmus\Cela3a, Mmus\Mst1, Mmus\Tmprss6, Mmus\F12, Mmus\Hgf, Mmus\F2, Mmus\Tmprss9, Mmus\F10" "Hsap\PLAT, Hsap\F2, Hsap\PROC, Hsap\PLAU, Hsap\MST1L, Hsap\F12, Hsap\ST14, Hsap\HGFAC, Hsap\F10, Hsap\PRSS12, Hsap\MASP1, Hsap\HABP2, Hsap\F9, Hsap\PLG, Hsap\MST1, Hsap\HGF, Hsap\TMPRSS11E, Hsap\TMPRSS6" FBgn0037446 Zif Zinc-finger protein http://flybase.org/reports/FBgn0037446 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay neuroblast proliferation ; GO:0007405 | inferred from direct assay establishment or maintenance of neuroblast polarity ; GO:0045196 | inferred from direct assay larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "anon-WO0118547.391, Zif, CG10267, ZIF, CC32" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG10267 11-Aug-17 DroID_v2017_08 "Drer\zgc:171422, Drer\znf408, Drer\si:dkey-253d23.2, Drer\zgc:113452, Drer\LOC100535506, Drer\si:ch211-89o9.6, Drer\si:dkeyp-2e4.8, Drer\si:dkey-56e3.3, Drer\si:ch211-241b2.4, Drer\zgc:174623" Scer\ZAP1 "Cele\lin-29, Cele\blmp-1, Cele\Y17G7B.22, Cele\ztf-23, Cele\M03D4.4, Cele\klf-3, Cele\let-391" - "Mmus\Zfp62, Mmus\Gm13212, Mmus\Zfp984, Mmus\Zscan5b, Mmus\Zfp113, Mmus\Zfp758, Mmus\Zfp24, Mmus\Zfp445, Mmus\Zfp110, Mmus\Zfp945, Mmus\Zfp810, Mmus\Zfp369, Mmus\Zfp12, Mmus\Zkscan8, Mmus\Zfp93, Mmus\Zfp708" "Hsap\ZNF611, Hsap\ZNF233, Hsap\ZNF888, Hsap\ZNF485, Hsap\ZNF732, Hsap\ZNF816, Hsap\ZNF117, Hsap\ZNF761, Hsap\ZNF200, Hsap\ZNF98, Hsap\ZNF845, Hsap\ZNF43, Hsap\ZNF211, Hsap\ZNF730, Hsap\ZNF28, Hsap\ZSCAN30, Hsap\ZNF480, Hsap\ZNF850, Hsap\ZNF570, Hsap\ZNF558, Hsap\ZNF492, Hsap\ZNF792, Hsap\ZNF721, Hsap\ZNF568, Hsap\ZFP28, Hsap\ZNF595, Hsap\ZNF560, Hsap\ZNF681, Hsap\RBAK-RBAKDN, Hsap\ZNF675, Hsap\ZNF468, Hsap\ZNF527" "neuroanatomy defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,female sterile,female semi-sterile,recessive" "neuroblast,somatic clone,supernumerary" DRSC12514 I -0.690583247 -2.09509372 0.195435511 -0.741777976 0.992794517 -0.307770294 FBgn0040273 Spt5 Spt5 http://flybase.org/reports/FBgn0040273 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with UniProtKB:O00267 "positive regulation of DNA-templated transcription, elongation ; GO:0032786 | inferred from sequence or structural similarity with UniProtKB:O00267 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with UniProtKB:O00267 dosage compensation ; GO:0007549 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from direct assay transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from sequence or structural similarity with UniProtKB:O00267 negative regulation of DNA-templated transcription, elongation ; GO:0032785 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype negative regulation of DNA-templated transcription, elongation ; GO:0032785 | inferred from sequence or structural similarity with UniProtKB:O00267 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with UniProtKB:O00267" polytene chromosome interband ; GO:0005705 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from physical interaction with UniProtKB:Q9W420 nuclear exosome (RNase complex) ; GO:0000176 | colocalizes_with inferred from direct assay FACT complex ; GO:0035101 | colocalizes_with inferred from physical interaction with UniProtKB:Q9W420 polytene chromosome puff ; GO:0005703 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay DSIF complex ; GO:0032044 | inferred from sequence or structural similarity with UniProtKB:O00267 "Spt5, DSIF, spt5, dDSIF, dSpt5, Dspt5, CG7626, SPT5" "IPR005824:KOW, IPR006645:NusG, N-terminal, IPR017071:Transcription elongation factor Spt5, IPR024945:Spt5 C-terminal domain, IPR014722:Ribosomal protein L2 domain 2, IPR005100:Transcription elongation factor Spt5, NGN domain, IPR022581:Spt5 transcription elongation factor, N-terminal, IPR008991:Translation protein SH3-like domain" CG7626 11-Aug-17 DroID_v2017_08 Drer\supt5h Scer\SPT5 Cele\spt-5 Xtro\supt5h Mmus\Supt5 Hsap\SUPT5H "non-enhancer of variegation,non-suppressor of variegation,lethal,recessive,viable,body color defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic segment,maternal effect,denticle belt,embryonic/first instar larval cuticle,mesothoracic tergum" DRSC07556 I -2.141694729 1.256176222 -0.491828722 0.468526252 0.041459882 1.049607709 FBgn0259243 Pka-R1 "Protein kinase, cAMP-dependent, regulatory subunit type 1" http://flybase.org/reports/FBgn0259243 protein_coding_gene cAMP-dependent protein kinase regulator activity ; GO:0008603 | inferred from sequence or structural similarity cAMP-dependent protein kinase regulator activity ; GO:0008603 | inferred from mutant phenotype "regulation of protein phosphorylation ; GO:0001932 | inferred from electronic annotation with InterPro:IPR012198 olfactory learning ; GO:0008355 | non-traceable author statement positive regulation of feeding behavior ; GO:2000253 | inferred from mutant phenotype inferred from genetic interaction with sNPF-R actin filament organization ; GO:0007015 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype cAMP-mediated signaling ; GO:0019933 | non-traceable author statement molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from direct assay oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype" cAMP-dependent protein kinase complex ; GO:0005952 | inferred from electronic annotation with InterPro:IPR012198 cAMP-dependent protein kinase complex ; GO:0005952 | inferred from sequence or structural similarity "Pka-R1, PkaR, CG42341, PKA, Pka-RI, 18304, PKA-RI, PKAr, pka-R1, RI, dPKA-RI, DRI, pkA, dr[[1]], CG18677, CdkR, CG3263, CG12452, PKA-R1, pKA, PKAi, PKa-R1, PKAR" "IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR014710:RmlC-like jelly roll fold, IPR000595:Cyclic nucleotide-binding domain, IPR003117:cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, IPR012198:cAMP-dependent protein kinase regulatory subunit" CG42341 11-Aug-17 DroID_v2017_08 "Drer\prkar2ab, Drer\prkar1b, Drer\prkar2aa, Drer\prkar2b, Drer\LOC103910215, Drer\prkar1ab, Drer\prkar1aa" Scer\BCY1 Cele\kin-2 "Xtro\prkar1a, Xtro\prkar2b, Xtro\prkar2a" "Mmus\Prkar2a, Mmus\Prkar1b, Mmus\Cnbd2, Mmus\Prkar2b, Mmus\Prkar1a" "Hsap\CNBD2, Hsap\PRKAR1B, Hsap\PRKAR1A, Hsap\PRKAR2B, Hsap\PRKAR2A" " embryonic stage -- adult stage , adult stage " adult head

DRSC11674 IE -0.048523439 -3.68264299 -0.999875848 -3.004900401 -0.375247981 -0.428576086 FBgn0020545 kraken kraken http://flybase.org/reports/FBgn0020545 - protein_coding_gene serine hydrolase activity ; GO:0017171 | non-traceable author statement response to toxic substance ; GO:0009636 | inferred from expression pattern digestion ; GO:0007586 | inferred from expression pattern - "CG3943, kraken, Kraken" "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG3943 11-Aug-17 DroID_v2017_08 Drer\serhl Scer\YGR015C Cele\W01A11.1 "Xtro\serhl, Xtro\serhl2" Mmus\Serhl Hsap\SERHL2 " embryonic stage | stage >=15 , larval stage | third instar , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 11-12 , embryonic stage | pre-blastoderm , embryonic stage | stage 13-15 , embryonic stage | stage 13 , embryonic stage | stage 11 " " gastric caecum

, ventral thoracic disc

, embryonic/larval midgut | anterior

, anterior midgut proper primordium

, posterior midgut proper primordium

, eye disc

, organism

, embryonic/larval posterior spiracle

, embryonic/larval hindgut

, embryonic/larval midgut

, embryonic/larval foregut

, embryonic/larval fat body

, embryonic/larval pharynx

" "viable,fertile" FBgn0024811 Crk Crk oncogene http://flybase.org/reports/FBgn0024811 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Pvr SH3/SH2 adaptor activity ; GO:0005070 | inferred from direct assay "border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of JNK cascade ; GO:0046330 | inferred from direct assay imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | traceable author statement ephrin receptor signaling pathway ; GO:0048013 | inferred from sequence or structural similarity with UniProtKB:P46108 regulation of actin cytoskeleton organization ; GO:0032956 | inferred from sequence or structural similarity with UniProtKB:P46108 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with UniProtKB:P46108 phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype" - "dCrk, DCrk, Dcrk, CRK, D-Crk, CG1587, dCRK, D-CRK, Crk, crk" "IPR000980:SH2 domain, IPR001452:SH3 domain, IPR011511:Variant SH3 domain" CG1587 11-Aug-17 DroID_v2017_08 "Drer\crk, Drer\crkl" Scer\LSB1 "Cele\gap-3, Cele\ced-2" "Xtro\crkl, Xtro\crk" "Mmus\Crk, Mmus\Crkl" "Hsap\CRK, Hsap\CRKL" " embryonic stage | stage >=13 , embryonic stage | stage 6,7 , embryonic stage | stage 8-12 , embryonic stage | stage 16 , embryonic stage -- adult stage , embryonic stage | stage 8 , embryonic stage | stage 13 " " ventral nerve cord

, mesoderm

, posterior embryonic/larval midgut

, embryonic procephalic segment

, anterior embryonic/larval midgut

, muscle fiber

, embryonic/larval visceral muscle

, cephalic furrow | vicinity of

, somatic mesoderm

, visceral mesoderm

" "lethal,recessive,viable,neuroanatomy defective" "thorax,border follicle cell,reticular neuropil associated glial cell,gamma Kenyon cell" FBgn0015929 dpa disc proliferation abnormal http://flybase.org/reports/FBgn0015929 FBgn0004127 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008047, InterPro:IPR018525 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008047, InterPro:IPR018525 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR008047 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype DNA replication ; GO:0006260 | traceable author statement MCM complex ; GO:0042555 | inferred from electronic annotation with InterPro:IPR008047 "Mcm4, MCM4, DmMcm4, 43Ca, DmMCM4, Dpa, l(2)43Ca, CG1616, dpa, mcm4, DmeMCM4, MCM4_DROME" "IPR001208:MCM domain, IPR003593:AAA+ ATPase domain, IPR008047:Mini-chromosome maintenance complex protein 4, IPR018525:Mini-chromosome maintenance, conserved site, IPR012340:Nucleic acid-binding, OB-fold, IPR033762:MCM OB domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027925:MCM N-terminal domain, IPR031327:Mini-chromosome maintenance protein" CG1616 11-Aug-17 DroID_v2017_08 Drer\mcm4 Scer\MCM4 Cele\mcm-4 Xtro\mcm4 Mmus\Mcm4 Hsap\MCM4 " embryonic stage | stage >=13 , larval stage | third instar , embryonic stage | stage >=12 , embryonic stage | stage 10-12 , embryonic stage | stage <=11 , embryonic stage | stage 16,17 , adult stage && oogenesis stage , adult stage | female && oogenesis stage " " embryonic brain

, embryonic/larval hindgut

, imaginal disc

, eye-antennal disc

, anterior embryonic/larval midgut

, Malpighian tubule

, embryonic central nervous system | presumptive

, epidermis

, gonad

, neuroblast

, oocyte

, peripheral nervous system

, optic lobe

, germline cell

, posterior embryonic/larval midgut

, nurse cell

" "some die during pupal stage,wild-type,lethal - all die before end of pupal stage,recessive,viable,visible" "mitotic cell cycle,mitotic metaphase,spindle,mitosis & nuclear chromosome,chromosome, centromeric region,imaginal disc,central nervous system,trichogen cell,mesothoracic tergum" FBgn0011260 Sema2a Semaphorin 2a http://flybase.org/reports/FBgn0011260 FBgn0062466 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V4A7 synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype sensory neuron axon guidance ; GO:0097374 | inferred from mutant phenotype inferred from genetic interaction with PlexB inferred from genetic interaction with PlexA dendrite guidance ; GO:0070983 | inferred from genetic interaction with Sema2b visual behavior ; GO:0007632 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype olfactory bulb axon guidance ; GO:0071678 | inferred from mutant phenotype drinking behavior ; GO:0042756 | inferred from mutant phenotype adult behavior ; GO:0030534 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity "Sema-2a, D-Sema2a, CT14922, l(2)03021, Dsema-II, sema-II, sema II, Sema2a, SemaII, 112/40, D-SemaII, dSema-II, semaII, D-semaII, D-Sema II, BcDNA:LD09561, D-Sema-II, CG4700, sema-2a, sema2a, sema 2a" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001627:Sema domain, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR027231:Semaphorin, IPR013783:Immunoglobulin-like fold" CG4700 11-Aug-17 DroID_v2017_08 "Drer\sema4ba, Drer\si:dkey-49n23.1, Drer\sema4gb, Drer\sema3fb, Drer\sema4ab, Drer\si:ch211-129c21.1, Drer\sema6e, Drer\si:ch211-168n16.1, Drer\si:ch211-113g11.6, Drer\LOC798168, Drer\sema5ba, Drer\sema3c, Drer\sema6a, Drer\sema3ga, Drer\sema3d, Drer\rttn, Drer\sema4d, Drer\sema4e, Drer\sema3e, Drer\sema3gb, Drer\sema7a, Drer\sema3h, Drer\sema6bb, Drer\sema5a, Drer\sema6dl, Drer\sema5bb, Drer\sema3fa, Drer\sema4c, Drer\sema3aa, Drer\stap2a, Drer\sema3ab, Drer\sema3bl, Drer\sema4ga, Drer\sema3b, Drer\sema6d" - "Cele\F23H12.5, Cele\smp-2, Cele\C36B7.5, Cele\mab-20, Cele\smp-1" "Xtro\sema3a, Xtro\sema4c, Xtro\sema4g, Xtro\sema6d, Xtro\sema4b, Xtro\sema3d, Xtro\sema3f, Xtro\sema3b, Xtro\sema3c, Xtro\sema4d, Xtro\sema5b, Xtro\sema6a, Xtro\sema4a, Xtro\sema6b" "Mmus\Sema3e, Mmus\Sema3c, Mmus\Sema3b, Mmus\Sema3a, Mmus\Sema7a, Mmus\Sema4f, Mmus\Sema5a, Mmus\Sema3d, Mmus\Sema4b, Mmus\Sema6c, Mmus\Sema6b, Mmus\Sema4a, Mmus\Sspo, Mmus\Sema5b, Mmus\Sema3g, Mmus\Sema6d, Mmus\Sema3f, Mmus\Sema4g, Mmus\Sema4c, Mmus\Sema4d, Mmus\Sema6a" "Hsap\SEMA4F, Hsap\SEMA5A, Hsap\SEMA4B, Hsap\SEMA4C, Hsap\SEMA4A, Hsap\SEMA4D, Hsap\SEMA4G, Hsap\SEMA6C, Hsap\SEMA5B, Hsap\SEMA7A, Hsap\SEMA3D, Hsap\SEMA3F, Hsap\SEMA3B, Hsap\SEMA3A, Hsap\SEMA6B, Hsap\SEMA3G, Hsap\SEMA6D, Hsap\SEMA3C, Hsap\SEMA3E, Hsap\SEMA6A" " embryonic stage | stage 10 , embryonic stage | stage >=15 , embryonic stage | stage >=14 , embryonic stage " " epidermis | stripes

, central nervous system | restricted

, hypodermal muscle of metathorax | ventral

, gonad

, sense organ | anterior

, embryonic neuron

" "viable,fertile,neuroanatomy defective,lethal,recessive,flightless,behavior defective" "synapse,abdominal ventral longitudinal muscle 2 & neuromuscular junction,abdominal ventral longitudinal muscle 3 & neuromuscular junction,abdominal ventral longitudinal muscle 4 & neuromuscular junction,abdominal segment border muscle & neuromuscular junction,neuromuscular junction | ectopic,abdominal lateral oblique muscle 1 & neuromuscular junction,intersegmental nerve,transverse nerve,abdominal segmental nerve,imaginal disc,abdominal 1 VO2 motor neuron,abdominal 2 VO2 motor neuron,abdominal 1 VL3/4 motor neuron,abdominal 2 VL3/4 motor neuron,RP3 motor neuron,intersegmental nerve branch ISNb of A1-7" FBgn0040227 eIF3d1 eukaryotic translation initiation factor 3 subunit d1 http://flybase.org/reports/FBgn0040227 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VSS1 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from direct assay regulation of translational initiation ; GO:0006446 | inferred from direct assay translational initiation ; GO:0006413 | inferred from sequence or structural similarity eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity "153314_at, eiF3p66, GM04979, CG10161, eIF3-S7, GM10514, BEST:GM10514, eIF-3p66, eIF3p66, eIF3d, eIF3d1" IPR007783:Eukaryotic translation initiation factor 3 subunit D CG10161 11-Aug-17 DroID_v2017_08 Drer\eif3d - Cele\eif-3.D Xtro\eif3d Mmus\Eif3d Hsap\EIF3D "visible,wild-type,long lived" eye DRSC16938 EK -0.673970952 -1.183548318 1.512784687 -0.369327199 1.533031702 3.980798532 FBgn0026582 Hmg-2 High mobility group protein 2 http://flybase.org/reports/FBgn0026582 FBgn0034594 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:1914117 "LD07122, BEST:LD07122, CG9418, Hmg-2" IPR009071:High mobility group box domain CG9418 11-Aug-17 DroID_v2017_08 "Drer\hmgb3b, Drer\tox, Drer\ubtfl, Drer\hmg20b, Drer\tox4a, Drer\tox4b, Drer\hmgb1b, Drer\tfam, Drer\tox3, Drer\hmgb3a, Drer\hmgb2b, Drer\hmg20a, Drer\hmgb2a, Drer\ubtf, Drer\hmgb1a" "Scer\RUD3, Scer\NHP6A, Scer\IXR1, Scer\ABF2, Scer\NHP10, Scer\HMO1, Scer\NHP6B" "Cele\hmg-20, Cele\hmg-1.1, Cele\hmg-1.2" "Xtro\hmgb3, Xtro\hmg20b, Xtro\hmgb2, Xtro\hmg20a, Xtro\tfam, Xtro\tox, Xtro\hmgb1, Xtro\tox4, Xtro\tox3, Xtro\tox2, Xtro\ubtf" "Mmus\Hmgb4, Mmus\Ubtf, Mmus\Gm21596, Mmus\Tox4, Mmus\Hmgb1, Mmus\Hmg20a, Mmus\Tox, Mmus\Ubtfl1, Mmus\Hmg20b, Mmus\Tox3, Mmus\Tfam, Mmus\Tox2, Mmus\Hmgb3, Mmus\Hmgb2" "Hsap\TOX2, Hsap\TOX, Hsap\HMG20A, Hsap\HMGB3, Hsap\HMGB1, Hsap\HMGB2, Hsap\TOX3, Hsap\TFAM, Hsap\HMGB4, Hsap\HMG20B, Hsap\CIC, Hsap\UBTF, Hsap\TOX4" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC04554 I 0.210395311 -2.182004598 -0.365023532 -0.458682818 -0.935016866 0.241862931 FBgn0283469 Vps4 Vacuolar protein sorting 4 http://flybase.org/reports/FBgn0283469 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with SGD:S000006377" vacuole organization ; GO:0007033 | inferred from biological aspect of ancestor with PANTHER:PTN000553912 autophagosome maturation ; GO:0097352 | inferred from mutant phenotype R8 cell development ; GO:0045463 | inferred from mutant phenotype R8 cell-mediated photoreceptor organization ; GO:0045470 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | inferred from mutant phenotype inferred from genetic interaction with Ras85D inferred from genetic interaction with Egfr inferred from genetic interaction with rho inferred from genetic interaction with spi negative regulation of growth of symbiont in host ; GO:0044130 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000006377 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000553509 Vps4-Vta1 complex ; GO:1990621 | inferred from sequence or structural similarity with SGD:S000006377 "Vps4, 3B1, vps4, DmBcDNA.GH02678, BcDNA:GH02678, bcDNA:GH02678, CG6842, Vps4B, dvps4, Dvps4" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR007330:MIT, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR015415:Vps4 oligomerisation, C-terminal" CG6842 11-Aug-17 DroID_v2017_08 "Drer\spast, Drer\fignl1, Drer\fign, Drer\katnal2, Drer\vps4b, Drer\katna1, Drer\vps4a, Drer\si:dkey-195m11.8, Drer\katnal1" "Scer\SAP1, Scer\VPS4" "Cele\figl-1, Cele\mei-1, Cele\vps-4, Cele\spas-1" "Xtro\spast, Xtro\fign, Xtro\katna1, Xtro\fignl1, Xtro\vps4a, Xtro\vps4b" "Mmus\Fign, Mmus\Katnal2, Mmus\Vps4a, Mmus\Spast, Mmus\Katnal1, Mmus\Fignl1, Mmus\Katna1, Mmus\Vps4b" "Hsap\VPS4A, Hsap\VPS4B, Hsap\SPAST, Hsap\KATNAL2, Hsap\KATNA1, Hsap\KATNAL1" DRSC19338 IEK -0.638358511 -2.86606776 0.120902631 -5.012199287 -2.682337979 -3.600187753 FBgn0015614 CanB2 Calcineurin B2 http://flybase.org/reports/FBgn0015614 FBgn0033220 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calmodulin binding ; GO:0005516 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with sra calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9XZL8 calcium-dependent protein serine/threonine phosphatase regulator activity ; GO:0008597 | inferred from sequence or structural similarity sleep ; GO:0030431 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity skeletal muscle myosin thick filament assembly ; GO:0030241 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype calcineurin complex ; GO:0005955 | inferred from sequence or structural similarity synaptic vesicle ; GO:0008021 | non-traceable author statement "CanB2, canB2, CG11217, CS2-1, dCnB2, dCNB2" "IPR011992:EF-hand domain pair, IPR002048:EF-hand domain, IPR018247:EF-Hand 1, calcium-binding site" CG11217 11-Aug-17 DroID_v2017_08 "Drer\chp2, Drer\LOC100536377, Drer\ppp3r1b, Drer\tesca, Drer\wdr92, Drer\ppp3r1a, Drer\chp1, Drer\tescb" Scer\CNB1 Cele\cnb-1 "Xtro\cib1, Xtro\wdr92, Xtro\ppp3r1, Xtro\chp1" "Mmus\Wdr92, Mmus\Ppp3r1, Mmus\Tesc, Mmus\Chp1, Mmus\Cib1, Mmus\Chp2, Mmus\Cib4, Mmus\Tescl, Mmus\Ppp3r2" "Hsap\CHP2, Hsap\PPP3R2, Hsap\CIB1, Hsap\CHP1, Hsap\TESC, Hsap\CIB4, Hsap\WDR92, Hsap\PPP3R1" pupal stage--adult stage "flightless,partially lethal - majority die,meiotic cell cycle defective,germline clone,female sterile,lethal,recessive,sleep defective,viable,visible,hyperactive,smell perception defective" "indirect flight muscle,dorsal medial muscle,wing,indirect flight muscle | P-stage,dorsal medial muscle | P-stage,myofibril[-],sarcomere[-],trichogen cell" FBgn0037490 CG10053 - http://flybase.org/reports/FBgn0037490 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467 - kinetochore ; GO:0000776 | inferred from biological aspect of ancestor with PANTHER:PTN000471210 "BEST:LD45537, BEST:LD41878, CG10053" "IPR025239:Domain of unknown function DUF4187, IPR000467:G-patch domain" CG10053 11-Aug-17 DroID_v2017_08 Drer\gpatch11 Scer\CMG1 "Cele\Y53F4B.13, Cele\T04H1.5" Xtro\gpatch11 Mmus\Gpatch11 Hsap\GPATCH11 viable FBgn0030699 CG8578 - http://flybase.org/reports/FBgn0030699 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab6 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR019139 adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype" - CG8578 IPR019139:Leucine-rich repeat flightless-interacting protein 1/2 CG8578 11-Aug-17 DroID_v2017_08 "Drer\lrrfip2, Drer\lrrfip1a, Drer\lrrfip1b" - Cele\flap-1 Xtro\lrrfip2 "Mmus\Ccdc150, Mmus\Lrrfip2, Mmus\Lrrfip1" "Hsap\LRRFIP2, Hsap\LRRFIP1" viable "indirect flight muscle,myofibrilMef2.PR" FBgn0029911 CG14435 - http://flybase.org/reports/FBgn0029911 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:2177308 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:2177308 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 cellular_component ; GO:0005575 | no biological data available CG14435 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG14435 11-Aug-17 DroID_v2017_08 "Drer\zgc:66427, Drer\znrf2a, Drer\znrf1, Drer\znrf2b" - "Cele\sdz-34, Cele\Y71F9AL.10, Cele\C09E7.8" Xtro\znrf1 "Mmus\Znrf2, Mmus\Znrf1" "Hsap\ZNRF1, Hsap\ZNRF2" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053884 His2B:CG33884 His2B:CG33884 http://flybase.org/reports/FBgn0053884 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33884, His2B:CG33884" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33884 11-Aug-17 DroID_v2017_08 "Drer\zgc:92591, Drer\LOC100329290, Drer\si:ch211-113a14.29, Drer\si:dkey-23a13.16, Drer\LOC100334869, Drer\si:ch211-113a14.28, Drer\si:ch1073-159d7.13, Drer\zgc:194989, Drer\zgc:112234, Drer\zgc:173587, Drer\ano9a, Drer\LOC100334559, Drer\si:dkey-261m9.6, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.5, Drer\LOC100329560, Drer\si:dkey-23a13.8, Drer\si:ch211-113a14.15, Drer\si:dkey-108k21.11, Drer\si:ch1073-153i20.3, Drer\si:ch73-368j24.10, Drer\hist2h2l, Drer\si:ch1073-159d7.5, Drer\zgc:114046, Drer\si:dkey-23a13.1, Drer\si:ch73-36p18.3, Drer\zgc:173585, Drer\hist1h2ba, Drer\si:dkey-108k21.27, Drer\si:ch73-368j24.8, Drer\si:dkey-261m9.19" "Scer\HTB2, Scer\HTB1" "Cele\his-4, Cele\his-22, Cele\his-54, Cele\his-52, Cele\his-34, Cele\his-8, Cele\his-39, Cele\his-62, Cele\his-44, Cele\his-20, Cele\his-66, Cele\his-48, Cele\his-29, Cele\his-41, Cele\his-15, Cele\his-11, Cele\his-58" "Xtro\LOC100498647, Xtro\hist2h2be, Xtro\LOC101731959, Xtro\LOC100497082, Xtro\LOC100495415, Xtro\LOC101735218, Xtro\LOC100496445, Xtro\LOC100498329, Xtro\hist1h2bm, Xtro\LOC100495578, Xtro\hist1h2bj, Xtro\LOC100498553, Xtro\LOC100485134, Xtro\LOC101733828, Xtro\LOC101734862, Xtro\LOC100496181, Xtro\LOC100496436, Xtro\LOC100495041, Xtro\LOC101730940, Xtro\LOC101735164, Xtro\LOC100495396, Xtro\LOC100498072, Xtro\LOC101734494, Xtro\LOC101733171, Xtro\LOC101733489, Xtro\LOC100492632, Xtro\LOC101731852, Xtro\LOC100486150, Xtro\LOC100486870, Xtro\LOC100487485, Xtro\LOC101731067, Xtro\LOC100497915, Xtro\LOC100485294, Xtro\hist1h2bk" "Mmus\Hist1h2bn, Mmus\Hist2h2bb, Mmus\Hist1h2bq, Mmus\Hist1h2bj, Mmus\Hist1h2bg, Mmus\Hist1h2bk, Mmus\Hist1h2bc, Mmus\1700024P04Rik, Mmus\Hist1h2bh, Mmus\Hist1h2ba, Mmus\H2bfm, Mmus\Hist1h2bf, Mmus\Hist3h2ba, Mmus\Hist2h2be, Mmus\Hist1h2br, Mmus\Hist1h2bm, Mmus\Hist1h2bb, Mmus\Hist1h2bp, Mmus\Hist1h2bl, Mmus\Hist1h2be" "Hsap\HIST1H2BO, Hsap\LOC102724334, Hsap\HIST1H2BE, Hsap\HIST1H2BM, Hsap\HIST1H2BN, Hsap\HIST1H2BA, Hsap\HIST1H2BJ, Hsap\HIST1H2BL, Hsap\HIST1H2BF, Hsap\H2BFM, Hsap\HIST1H2BC, Hsap\HIST1H2BG, Hsap\HIST3H2BB, Hsap\HIST1H2BH, Hsap\H2BFWT, Hsap\HIST1H2BD, Hsap\HIST1H2BI, Hsap\HIST2H2BF, Hsap\HIST2H2BE, Hsap\HIST1H2BB, Hsap\HIST1H2BK" FBgn0033465 Etf-QO Electron transfer flavoprotein-ubiquinone oxidoreductase http://flybase.org/reports/FBgn0033465 protein_coding_gene "electron-transferring-flavoprotein dehydrogenase activity ; GO:0004174 | inferred from sequence or structural similarity with UniProtKB:Q16134 electron-transferring-flavoprotein dehydrogenase activity ; GO:0004174 | inferred from direct assay electron carrier activity ; GO:0009055 | inferred from biological aspect of ancestor with PANTHER:PTN000835262 ubiquinone binding ; GO:0048039 | inferred from biological aspect of ancestor with PANTHER:PTN000835262 oxidoreductase activity, oxidizing metal ions with flavin as acceptor ; GO:0043783 | inferred from biological aspect of ancestor with PANTHER:PTN000835262 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from biological aspect of ancestor with PANTHER:PTN000835262" respiratory electron transport chain ; GO:0022904 | inferred from biological aspect of ancestor with PANTHER:PTN000835262 fatty acid beta-oxidation ; GO:0006635 | inferred from mutant phenotype oxidative phosphorylation ; GO:0006119 | inferred from sequence or structural similarity with UniProtKB:Q16134 microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrial electron transfer flavoprotein complex ; GO:0017133 | inferred from biological aspect of ancestor with PANTHER:PTN000065332 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q16134 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000065332 "CG12140, CG 12140, Etf-QO, ETF:QO, ETFD, ETFDH" IPR023753:FAD/NAD(P)-binding domain CG12140 11-Aug-17 DroID_v2017_08 Drer\etfdh Scer\CIR2 Cele\let-721 Xtro\etfdh Mmus\Etfdh Hsap\ETFDH "increased cell death,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,viable" embryonic/larval cuticle FBgn0031214 CG11374 - http://flybase.org/reports/FBgn0031214 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR001079 - - CG11374 "IPR001079:Galectin, carbohydrate recognition domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG11374 11-Aug-17 DroID_v2017_08 "Drer\lgals9l1, Drer\si:ch211-10a23.2, Drer\si:dkey-151j17.4, Drer\lgalslb, Drer\lgals3a, Drer\lgals1l1, Drer\lgals9l6, Drer\lgals3b, Drer\lgals9l5, Drer\grifin, Drer\lgals8b, Drer\lgals8a, Drer\lgals9l3, Drer\lgals9l4, Drer\lgalsla" - "Cele\lec-12, Cele\lec-2, Cele\M6.11, Cele\lec-11, Cele\lec-9, Cele\lec-10, Cele\lec-6, Cele\lec-8, Cele\lec-7" "Xtro\lgals2, Xtro\lgalsl, Xtro\lgals9, Xtro\LOC100496749, Xtro\lgals4, Xtro\lgals3, Xtro\lgals9c, Xtro\lgals8, Xtro\lgals1, Xtro\LOC100216286, Xtro\lgals9b" "Mmus\Lgalsl, Mmus\Grifin, Mmus\Lgals3, Mmus\Lgals2, Mmus\Lgals6, Mmus\Lgals12, Mmus\Lgals1, Mmus\Lgals9, Mmus\Lgals8, Mmus\Lgals7, Mmus\Lgals4" "Hsap\LGALS4, Hsap\LGALSL, Hsap\LGALS9, Hsap\LGALS12, Hsap\LGALS7, Hsap\CLC, Hsap\LGALS9B, Hsap\LGALS8, Hsap\LGALS9C, Hsap\LGALS1, Hsap\LGALS13, Hsap\OSTC, Hsap\LGALS14, Hsap\LGALS7B, Hsap\LGALS3, Hsap\LGALS2" viable FBgn0032949 Lamp1 Lamp1 http://flybase.org/reports/FBgn0032949 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002000 lysosome ; GO:0005764 | inferred from direct assay "CG3305, Lamp1, LAMP1, Lamp, Lamp-1, lamp1, dLAMP, dLamp, LAMP" IPR002000:Lysosome-associated membrane glycoprotein CG3305 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-212k18.7, Drer\zgc:165600, Drer\lamp1, Drer\lamp2, Drer\zgc:64072" - "Cele\lmp-1, Cele\lmp-2" "Xtro\lamp1, Xtro\lamp2" "Mmus\Lamp3, Mmus\Cd68, Mmus\Lamp5, Mmus\Lamp1, Mmus\Lamp2" "Hsap\LAMP3, Hsap\LAMP1, Hsap\CD68, Hsap\LAMP2, Hsap\LAMP5" "neuroanatomy defective,conditional,viable,fertile,decreased cell death,recessive,somatic clone" "dorsal multidendritic neuron ddaC | pupal stage,dorsal multidendritic neuron ddaC,conditional" FBgn0015351 CG14906 - http://flybase.org/reports/FBgn0015351 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002052 site-specific DNA-methyltransferase (adenine-specific) activity ; GO:0009007 | inferred from biological aspect of ancestor with PANTHER:PTN000375324 nucleobase-containing compound metabolic process ; GO:0006139 | inferred from electronic annotation with InterPro:IPR007757 methylation ; GO:0032259 | inferred from electronic annotation with InterPro:IPR002052 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000302827 "ORF2, anon-89Eb, CG14906" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR007757:MT-A70-like, IPR002052:DNA methylase, N-6 adenine-specific, conserved site" CG14906 11-Aug-17 DroID_v2017_08 Drer\mettl4 - Cele\C18A3.1 Xtro\mettl4 Mmus\Mettl4 Hsap\METTL4 "viable,fertile" DRSC26716 K 1.343712903 -0.579608899 0.453300475 0.340057196 1.523059117 -0.356035364 FBgn0032131 CG3841 - http://flybase.org/reports/FBgn0032131 protein_coding_gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3841 "IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold, IPR002018:Carboxylesterase, type B" CG3841 11-Aug-17 DroID_v2017_08 "Drer\cel.1, Drer\cell, Drer\ces2, Drer\nlgn4a, Drer\nlgn3a, Drer\si:ch211-93f2.1, Drer\ces3, Drer\nlgn1, Drer\nlgn3b, Drer\si:ch211-71n6.4, Drer\nlgn4b, Drer\nlgn2b, Drer\nlgn2a" - "Cele\F15A8.6, Cele\ZC376.2, Cele\R173.3, Cele\K11G9.1, Cele\C17H12.4, Cele\Y71H2AM.13, Cele\T22D1.11, Cele\K11G9.3, Cele\F56C11.6, Cele\T07H6.1, Cele\ZK994.1, Cele\C23H4.3, Cele\T28C12.4, Cele\K11G9.2, Cele\C23H4.7, Cele\B0238.1, Cele\E01G6.3, Cele\C42D4.2, Cele\ZC376.1, Cele\C01B10.10, Cele\C01B10.4, Cele\C52A10.1, Cele\T02B5.1, Cele\ges-1, Cele\F13H6.3, Cele\ZC376.3, Cele\F07C4.12, Cele\T02B5.3, Cele\T28C12.5, Cele\C23H4.2, Cele\C23H4.4" "Xtro\nlgn2, Xtro\cel, Xtro\ces3, Xtro\LOC100494782, Xtro\ces2, Xtro\nlgn3, Xtro\nlgn4x" "Mmus\Cel, Mmus\Nlgn3, Mmus\Ces1a, Mmus\Ces5a, Mmus\Ces2g, Mmus\Nlgn2, Mmus\Nlgn1, Mmus\Ces2f, Mmus\Ces1h, Mmus\Ces2h, Mmus\Ces1b, Mmus\Ces1d, Mmus\Ces2c, Mmus\Ces3b, Mmus\Ces2b, Mmus\Ces2a, Mmus\Ces1e, Mmus\Ces1g, Mmus\Ces3a, Mmus\Ces2e, Mmus\Ces1c, Mmus\Ces1f, Mmus\Bche, Mmus\Ces4a" "Hsap\NLGN3, Hsap\CES2, Hsap\CES1, Hsap\CES4A, Hsap\NLGN1, Hsap\CEL, Hsap\NLGN4X, Hsap\NLGN4Y, Hsap\BCHE, Hsap\CES3, Hsap\CES5A, Hsap\NLGN2" viable FBgn0035082 CG2811 - http://flybase.org/reports/FBgn0035082 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE67445, CG2811" "IPR009288:Gamma-glutamylcyclotransferase, AIG2-like, IPR013024:Gamma-glutamyl cyclotransferase-like" CG2811 11-Aug-17 DroID_v2017_08 "Drer\ggact.1, Drer\ggact.3, Drer\ggact.2" - Cele\F42A10.9 Xtro\ggact Mmus\Ggact Hsap\GGACT viable DRSC04318 I 3.229163886 -0.62089587 -0.04810969 0.427897583 0.427894251 1.072220096 FBgn0033502 CG12910 - http://flybase.org/reports/FBgn0033502 protein_coding_gene - - - CG12910 IPR008166:Glycosyltransferase family 92 CG12910 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-211l2.1, Drer\si:dkey-56i24.1, Drer\zgc:194839, Drer\si:zfos-464b6.2" - "Cele\F46F5.7, Cele\T06A1.1, Cele\T05B11.4, Cele\D1014.5, Cele\K08D9.2, Cele\C05C8.8, Cele\C14C6.8, Cele\D1014.7, Cele\C08B6.3, Cele\C18G1.7, Cele\R05A10.6, Cele\ZK488.5, Cele\C13A2.2, Cele\T06A1.5, Cele\C14C6.6, Cele\T15D6.12, Cele\bah-1, Cele\Y105C5B.25, Cele\F28H7.7, Cele\Y47D3B.4, Cele\ZK488.6, Cele\C17A2.2, Cele\D1014.6, Cele\galt-1, Cele\T15D6.10, Cele\R08C7.4, Cele\C31B8.7, Cele\K06H6.4, Cele\F54D10.8, Cele\ZK1025.4, Cele\F39G3.2, Cele\C01G5.9, Cele\F36F12.3" "Xtro\LOC100495879, Xtro\LOC100492375, Xtro\LOC100145503" - - viable FBgn0034389 Mctp Multiple C2 domain and transmembrane region protein http://flybase.org/reports/FBgn0034389 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with HGNC:26183 negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:26183 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000080880 "CG15078, DmMCTP, CG33146, CG33148, Mctp" "IPR000008:C2 domain, IPR013583:Phosphoribosyltransferase C-terminal" CG15078 11-Aug-17 DroID_v2017_08 "Drer\mctp2b, Drer\esyt2b, Drer\mctp1a, Drer\mctp1b, Drer\mctp2a, Drer\esyt2a, Drer\esyt3" "Scer\TCB3, Scer\TCB2, Scer\TCB1, Scer\INN1" "Cele\mctp-1, Cele\esyt-2, Cele\snt-2" "Xtro\mctp2, Xtro\esyt3, Xtro\mctp1" "Mmus\Mctp1, Mmus\Esyt1, Mmus\Mctp2, Mmus\Esyt3, Mmus\Esyt2" "Hsap\MCTP2, Hsap\ESYT1, Hsap\ESYT3, Hsap\MCTP1, Hsap\ESYT2" "viable,fertile,lethal" FBgn0003008 or orange http://flybase.org/reports/FBgn0003008 FBgn0034944 protein_coding_gene "protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with AP-1σ, AP-2σ" intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR000804 vesicle-mediated transport ; GO:0016192 | inferred from electronic annotation with InterPro:IPR000804 compound eye pigmentation ; GO:0048072 | inferred from genetic interaction with p ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype eye pigment biosynthetic process ; GO:0006726 | traceable author statement lysosome organization ; GO:0007040 | inferred from sequence or structural similarity intracellular transport ; GO:0046907 | traceable author statement vesicle coating ; GO:0006901 | traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle coating ; GO:0016183 | traceable author statement synaptic vesicle ; GO:0008021 | traceable author statement AP-3 adaptor complex ; GO:0030123 | inferred from sequence or structural similarity with HGNC:571 coated vesicle ; GO:0030135 | traceable author statement "or, CG3029, cg3029, sigma3, AP-3sigma, Or, aps3" "IPR000804:Clathrin adaptor complex, small chain, IPR011012:Longin-like domain, IPR016635:Adaptor protein complex, sigma subunit, IPR022775:AP complex, mu/sigma subunit" CG3029 11-Aug-17 DroID_v2017_08 "Drer\arpin, Drer\ap1s3b, Drer\ap2s1, Drer\ap3s2, Drer\ap1s1, Drer\ap1s3a, Drer\ap3s1" Scer\APS3 "Cele\aps-1, Cele\aps-3, Cele\aps-2" "Xtro\ap3s2, Xtro\ap1s3, Xtro\arpin, Xtro\ap3s1, Xtro\ap1s2, Xtro\ap1s1, Xtro\ap2s1" "Mmus\Ap3s2, Mmus\Arpin, Mmus\Ap3s1, Mmus\Ap2s1, Mmus\Ap1s2, Mmus\Ap1s3" "Hsap\AP1S3, Hsap\AP1S2, Hsap\ARPIN, Hsap\AP3S2, Hsap\AP3S1, Hsap\AP1S1, Hsap\AP2S1, Hsap\C15orf38-AP3S2" "viable,fertile,eye color defective,visible,recessive,somatic clone,locomotor behavior defective" "photoreceptor cell pigment granule,pigment cell,somatic clone,mesothoracic tergum" FBgn0061469 Ube3a Ubiquitin protein ligase E3A http://flybase.org/reports/FBgn0061469 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from mutant phenotype negative regulation of BMP signaling pathway ; GO:0030514 | inferred from mutant phenotype inferred from genetic interaction with tkv inferred from genetic interaction with Mad dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from genetic interaction with Rpn10 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype peripheral nervous system neuron development ; GO:0048935 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "dube3A, CG6190, das, dube3a, ube3a, As, Dube3a, UBE3A, dUBE3A, Ube3a, AS, NM_140195.2, Dube3A, dUbe3a" "IPR000569:HECT domain, IPR017134:Ubiquitin-protein ligase E3A, IPR032353:Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain" CG6190 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-281g13.5, Drer\herc4, Drer\si:ch211-281g13.4, Drer\ube3a, Drer\herc3, Drer\zgc:163136, Drer\hectd2, Drer\si:ch73-190m4.1" Scer\HUL4 - "Xtro\herc6, Xtro\herc4, Xtro\herc3, Xtro\ube3a" "Mmus\Herc6, Mmus\Herc4, Mmus\Ube3a, Mmus\Hectd2, Mmus\Herc3" "Hsap\HERC4, Hsap\UBE3A, Hsap\HERC3, Hsap\HECTD2, Hsap\HERC6, Hsap\HERC5" "locomotor behavior defective,viable,neuroanatomy defective,lethal,male limited,recessive,fertile,chemosensitive behavior defective,gravitaxis defective,memory defective,locomotor rhythm defective,wild-type,size defective" "wing margin,eye,ommatidium,photoreceptor cell,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaF,dorsal multidendritic neuron ddaC,retina,wing,interommatidial bristle" FBgn0025469 slv saliva http://flybase.org/reports/FBgn0025469 FBgn0025735 protein_coding_gene sugar transmembrane transporter activity ; GO:0051119 | inferred from sequence or structural similarity with UniProtKB:Q8L9J7 sugar transmembrane transporter activity ; GO:0051119 | inferred from biological aspect of ancestor with PANTHER:PTN000846358 salivary gland development ; GO:0007431 | inferred from expression pattern carbohydrate transport ; GO:0008643 | inferred from biological aspect of ancestor with PANTHER:PTN000846358 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000846358 "CG8717, slv" IPR004316:SWEET sugar transporter CG8717 11-Aug-17 DroID_v2017_08 Drer\slc50a1 Scer\SSN2 "Cele\swt-4, Cele\swt-1, Cele\swt-3, Cele\swt-7, Cele\swt-2, Cele\swt-5, Cele\swt-6" Xtro\slc50a1 Mmus\Slc50a1 Hsap\SLC50A1 " embryonic stage -- adult stage , embryonic stage | stage >=11 " salivary gland body primordium

"neuroanatomy defective,viable" "mushroom body & axon7B,Kenyon cell" DRSC07685 K -0.645730842 0.336846528 0.17246838 0.239703586 -1.002599646 -1.603142114 FBgn0024227 aurB aurora B http://flybase.org/reports/FBgn0024227 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:11390 histone serine kinase activity ; GO:0035174 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 protein serine/threonine/tyrosine kinase activity ; GO:0004712 | inferred from direct assay" histone H3-S28 phosphorylation ; GO:0043988 | inferred from electronic annotation with InterPro:IPR028772 positive regulation of cytokinesis ; GO:0032467 | inferred from electronic annotation with InterPro:IPR028772 spindle checkpoint ; GO:0031577 | inferred from electronic annotation with InterPro:IPR028772 chromatin organization ; GO:0006325 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype regulation of cytokinesis ; GO:0032465 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 protein phosphorylation ; GO:0006468 | non-traceable author statement cell separation after cytokinesis ; GO:0000920 | inferred from mutant phenotype histone phosphorylation ; GO:0016572 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity mitotic cytokinesis ; GO:0000281 | inferred from genetic interaction with shrb female germ-line stem cell asymmetric division ; GO:0048132 | inferred from genetic interaction with shrb mitotic spindle organization ; GO:0007052 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 attachment of spindle microtubules to kinetochore ; GO:0008608 | traceable author statement mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype "condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay spindle ; GO:0005819 | traceable author statement spindle ; GO:0005819 | inferred from direct assay kinetochore ; GO:0000776 | traceable author statement chromosome passenger complex ; GO:0032133 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay spindle pole centrosome ; GO:0031616 | inferred from biological aspect of ancestor with PANTHER:PTN000681967 meiotic spindle midzone ; GO:1990385 | colocalizes_with inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay spindle microtubule ; GO:0005876 | inferred from biological aspect of ancestor with PANTHER:PTN000681967" "Aurora-B, aurora B, AurB, IAL1, DmAurB, DmAuroraB, aurB, CG6620, IAL, DmAIRK2, Ial, Aur B, Aurora B, ial, ial/AurB, ABK" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR030616:Aurora kinase, IPR028772:Aurora kinase B" CG6620 11-Aug-17 DroID_v2017_08 "Drer\aurkb, Drer\aurka" Scer\IPL1 "Cele\air-1, Cele\air-2" "Xtro\aurkb, Xtro\aurka" "Mmus\Gm7207, Mmus\Aurka, Mmus\Pim2, Mmus\Aurkb, Mmus\Aurkc" "Hsap\AURKA, Hsap\AURKB, Hsap\PIM2, Hsap\AURKC" " embryonic stage | syncytial blastoderm , embryonic stage | stage 11-13 , embryonic stage | stage >=7 , embryonic stage | stage >=14 , adult stage && oogenesis stage | stage S9-10 , adult stage && oogenesis stage | stage >=S9 , embryonic stage -- adult stage , adult stage && oogenesis stage " " ventral nerve cord | segmentally repeated

,

segmentally repeated , ventral nerve cord | restricted

, nurse cell

, oocyte

" adult stage && oogenesis stage ovariole

"mitotic cell cycle defective,cytokinesis defective,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,increased cell size" "mitotic cell cycle, with aurBcGa,mitosis & nuclear chromosome, with aurBcGa,mitotic anaphase, with aurBcGa,mitotic cell cycle & chromosome, pericentric region, with aurBcGa,mitotic cell cycle & spindle, with aurBcGa,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,mitotic cell cycle,mitotic prometaphase & nuclear chromosome,spindle,mitotic cell cycle, with aurBa.cGa,mitosis & nuclear chromosome, with aurBa.cGa,mitotic anaphase, with aurBa.cGa,mitotic cell cycle & chromosome, pericentric region, with aurBa.cGa,mitotic cell cycle & spindle, with aurBa.cGa,nucleus" FBgn0015229 glec gliolectin http://flybase.org/reports/FBgn0015229 - protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from direct assay carbohydrate binding ; GO:0030246 | non-traceable author statement cell adhesion ; GO:0007155 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from expression pattern inferred from mutant phenotype heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay "CG6575, glec" - CG6575 11-Aug-17 DroID_v2017_08 - - - - - - embryonic stage | stage 11-15 ectoderm

segmentally repeated embryonic stage | stage 13-15 midline glial cell

"partially lethal - majority die,visible,lethal,recessive,viable" "scutellar bristle,trichogen cell,macrochaeta,germline cell,male,ventral nerve cord commissure,pCC neuron" FBgn0267384 Ubc7 Ubiquitin conjugating enzyme 7 http://flybase.org/reports/FBgn0267384 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12482 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000629793 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000629793 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12482 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "CG4443, Crl, col, Ubc47D, Ubc7, UBC7, crl, UbcD7" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG4443 11-Aug-17 DroID_v2017_08 "Drer\ube2g2, Drer\cdc34b, Drer\cdc34a, Drer\ube2g1a, Drer\ube2g1b" "Scer\CDC34, Scer\UBC7" "Cele\ubc-14, Cele\ubc-7" "Xtro\cdc34, Xtro\ube2g1, Xtro\ube2r2, Xtro\ube2g2" "Mmus\Ube2r2, Mmus\Ube2g1, Mmus\Ube2g2" "Hsap\CDC34, Hsap\UBE2G1, Hsap\UBE2R2, Hsap\UBE2G2" " embryonic stage -- adult stage , adult stage | male , embryonic stage | stage 10 , embryonic stage | stage 15 , embryonic stage | stage 6 , embryonic stage | stage 4 " " embryonic neuroblast

, embryonic central nervous system

, cephalic furrow

, stomodeal invagination

, mesoderm

" " embryonic stage | stage 7-8 , embryonic stage | stage 13-17 , embryonic stage | blastoderm " " endoderm

, embryonic central nervous system

, mesoderm

" FBgn0265052 St3 Sulfotransferase 3 http://flybase.org/reports/FBgn0265052 protein_coding_gene sulfotransferase activity ; GO:0008146 | inferred from direct assay sulfation ; GO:0051923 | inferred from direct assay xenobiotic metabolic process ; GO:0006805 | inferred from direct assay defense response to bacterium ; GO:0042742 | inferred from mutant phenotype cytosol ; GO:0005829 | non-traceable author statement "CG44167, CG5431, dmST3, St3, CG11293, st3" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000863:Sulfotransferase domain" CG44167 11-Aug-17 DroID_v2017_08 "Drer\sult2st3, Drer\sult1st4, Drer\sult3st4, Drer\sult1st3, Drer\sult2st2, Drer\sult1st5, Drer\sult6b1, Drer\sult4a1, Drer\sult1st7, Drer\sult3st2, Drer\si:dkey-236e20.3, Drer\sult1st1, Drer\sult1st2, Drer\sult2st1, Drer\sult3st1, Drer\sult3st3, Drer\sult1st8, Drer\sult1st6, Drer\sult5a1" - "Cele\C03C10.5, Cele\ssu-1" "Xtro\LOC100497264, Xtro\sult6b1, Xtro\sult1a1, Xtro\sult1c2, Xtro\LOC496998, Xtro\sult2b1, Xtro\sult4a1, Xtro\sult1e1" "Mmus\Sult2a8, Mmus\Sult2a7, Mmus\Sult6b2, Mmus\Sult2a3, Mmus\Sult2a1, Mmus\Sult1b1, Mmus\Sult1a1, Mmus\Sult2a6, Mmus\Sult1d1, Mmus\Sult1c1, Mmus\Sult4a1, Mmus\Sult1c2, Mmus\Sult2a2, Mmus\Sult1e1, Mmus\Sult2a4, Mmus\Sult5a1, Mmus\Sult3a1, Mmus\Sult6b1, Mmus\Sult2b1, Mmus\Sult3a2, Mmus\Sult2a5" "Hsap\SULT6B1, Hsap\SULT1A4, Hsap\SULT4A1, Hsap\SULT1C4, Hsap\SULT1E1, Hsap\SULT1A3, Hsap\SULT2B1, Hsap\SULT2A1, Hsap\SULT1A2, Hsap\SULT1B1, Hsap\SULT1A1, Hsap\SULT1C2, Hsap\SULT1C3" FBgn0259697 nvd neverland http://flybase.org/reports/FBgn0259697 protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR017941 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR017941" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR017941 ecdysteroid biosynthetic process ; GO:0045456 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype multicellular organism growth ; GO:0035264 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype - "nvd, CG40050, nvd-Dm, Nvd" IPR017941:Rieske [2Fe-2S] iron-sulphur domain CG40050 11-Aug-17 DroID_v2017_08 Drer\zgc:92275 - Cele\daf-36 Xtro\LOC100216141 - - FBgn0051611 His4:CG31611 His4:CG31611 http://flybase.org/reports/FBgn0051611 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR004823, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG31611, His4:CG31611" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG31611 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-261m9.17, Drer\LOC100329358, Drer\si:dkey-108k21.28, Drer\si:dkey-261m9.18, Drer\si:ch73-36p18.4, Drer\LOC570405, Drer\LOC562770, Drer\LOC100150038, Drer\si:dkey-108k21.12, Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.17, Drer\hist1h4l, Drer\si:ch73-36p18.3, Drer\zgc:163040, Drer\si:ch73-368j24.1, Drer\si:ch73-368j24.14, Drer\zgc:194989, Drer\si:ch211-113a14.6, Drer\zgc:153409, Drer\zgc:154164, Drer\LOC794549, Drer\si:ch211-113a14.26, Drer\LOC100331412, Drer\si:dkey-108k21.19" "Scer\HHF2, Scer\HHF1" "Cele\his-60, Cele\his-46, Cele\his-31, Cele\his-50, Cele\his-1, Cele\his-67, Cele\his-10, Cele\his-37, Cele\his-56, Cele\his-64, Cele\his-18, Cele\his-26, Cele\his-14, Cele\his-5, Cele\his-38, Cele\his-28" "Xtro\hist1h4c, Xtro\LOC100493041, Xtro\hist1h4k, Xtro\hist1h4a, Xtro\LOC100485271" "Mmus\Hist1h4h, Mmus\Hist1h4n, Mmus\Hist4h4, Mmus\Hist1h4j, Mmus\Hist1h4b, Mmus\Hist1h4k, Mmus\Hist2h4, Mmus\Hist1h4m, Mmus\Hist1h4i, Mmus\Hist1h4f, Mmus\Hist1h4a, Mmus\Hist1h4c, Mmus\Hist1h4d" "Hsap\HIST1H4L, Hsap\HIST1H4F, Hsap\HIST4H4, Hsap\HIST1H4C, Hsap\HIST2H4A, Hsap\HIST2H4B, Hsap\HIST1H4D, Hsap\HIST1H4E, Hsap\HIST1H4I, Hsap\HIST1H4H, Hsap\HIST1H4B, Hsap\HIST1H4K, Hsap\HIST1H4A, Hsap\HIST1H4G, Hsap\HIST1H4J" "viable,fertile" DRSC21268 IE -3.179513886 -3.964253834 -1.486507778 -5.104496797 -0.404127919 0.984476879 FBgn0024733 RpL10 Ribosomal protein L10 http://flybase.org/reports/FBgn0024733 "FBan0017521, FBgn0026279, FBgn0064923" protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001197, InterPro:IPR016180, InterPro:IPR018255 centrosome organization ; GO:0051297 | inferred from mutant phenotype ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000197715 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype" cytosolic ribosome ; GO:0022626 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "RpL10, DQM, anon-EST:Posey179, CG17521, BcDNA:LD24589, Qm, L10, Rp L10, qm" "IPR018255:Ribosomal protein L10e, conserved site, IPR001197:Ribosomal protein L10e, IPR016180:Ribosomal protein L10e/L16" CG17521 11-Aug-17 DroID_v2017_08 Drer\rpl10 Scer\RPL10 Cele\rpl-10 Xtro\rpl10 "Mmus\Rpl10l, Mmus\Gm5621, Mmus\Rpl10" "Hsap\RPL10L, Hsap\RPL10" lethal DRSC11947 IEK -1.960887705 -2.572967388 -0.703076538 -4.272006674 3.099004985 3.442780039 FBgn0037955 CG6950 - http://flybase.org/reports/FBgn0037955 protein_coding_gene kynurenine aminotransferase activity ; GO:0036137 | inferred from electronic annotation with InterPro:IPR034612 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR034612 kynurenine metabolic process ; GO:0070189 | inferred from electronic annotation with InterPro:IPR034612 biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004839 - CG6950 "IPR004839:Aminotransferase, class I/classII, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase, IPR034612:Kynurenine--oxoglutarate transaminase 3" CG6950 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-180m24.3, Drer\ccbl2, Drer\si:ch73-97h19.2, Drer\LOC100332215, Drer\ccbl1, Drer\LOC103911233" Scer\BNA3 "Cele\nkat-3, Cele\nkat-1" "Xtro\ccbl2, Xtro\ccbl1" "Mmus\Kyat3, Mmus\Kyat1" "Hsap\KYAT1, Hsap\KYAT3" "viable,fertile" FBgn0015040 Cyp9c1 Cytochrome P450-9c1 http://flybase.org/reports/FBgn0015040 - protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CG3616, 9c1, P450, P-450, Cyp9c1, CYP9C1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG3616 11-Aug-17 DroID_v2017_08 "Drer\cyp3c2, Drer\cyp3a65, Drer\cyp4t8, Drer\cyp3c4, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp4f3, Drer\cyp26a1, Drer\tbxas1" "Scer\ERG11, Scer\ERG5" "Cele\cyp-13A1, Cele\cyp-29A2, Cele\cyp-13A5, Cele\cyp-25A4, Cele\cyp-13A6, Cele\cyp-13A11, Cele\cyp-13B1, Cele\cyp-32A1, Cele\cyp-25A2, Cele\cyp-13A3, Cele\cyp-29A4, Cele\cyp-13A10, Cele\cyp-13A8, Cele\cyp-37B1, Cele\cyp-29A3, Cele\cyp-13A7, Cele\cyp-13A12, Cele\cyp-31A3, Cele\cyp-13A2, Cele\cyp-31A2, Cele\cyp-13A4, Cele\cyp-13B2, Cele\cyp-25A6, Cele\cyp-32B1, Cele\cyp-25A1, Cele\cyp-44A1, Cele\cyp-42A1, Cele\cyp-43A1, Cele\cyp-25A3" "Xtro\LOC100494419, Xtro\cyp3a4, Xtro\tbxas1, Xtro\cyp3a5" "Mmus\Cyp3a25, Mmus\Cyp4f39, Mmus\Cyp4f37, Mmus\Cyp4f15, Mmus\Cyp3a59, Mmus\Cyp3a44, Mmus\Cyp3a57, Mmus\Cyp4v3, Mmus\Cyp4a12a, Mmus\Cyp4f18, Mmus\Cyp4f14, Mmus\Cyp4f16, Mmus\Cyp3a41b, Mmus\Cyp4a12b, Mmus\Cyp3a41a, Mmus\Cyp3a11, Mmus\Cyp3a16, Mmus\Cyp4a14, Mmus\Tbxas1, Mmus\Cyp4b1, Mmus\Cyp4f13, Mmus\Cyp4a31, Mmus\Cyp26a1, Mmus\Cyp3a13, Mmus\Cyp4a32, Mmus\Cyp4a10" "Hsap\CYP4B1, Hsap\CYP4F11, Hsap\CYP4F12, Hsap\CYP3A5, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A43, Hsap\CYP4F22, Hsap\CYP4A22, Hsap\CYP4A11, Hsap\CYP4X1, Hsap\CYP3A4, Hsap\CYP4V2, Hsap\CYP26A1, Hsap\CYP3A7, Hsap\TBXAS1, Hsap\CYP4F3, Hsap\CYP4Z1, Hsap\CYP4F2, Hsap\CYP4F8" FBgn0034624 CG17974 - http://flybase.org/reports/FBgn0034624 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model CG17974 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG17974 11-Aug-17 DroID_v2017_08 "Drer\glipr1b, Drer\glipr2l, Drer\r3hdml, Drer\pi15b, Drer\glipr2, Drer\pi15a, Drer\LOC101883528, Drer\LOC100536500, Drer\crispld1b, Drer\crispld2, Drer\crispld1a" "Scer\PRY1, Scer\PRY2, Scer\PRY3" "Cele\scl-27, Cele\scl-14, Cele\scl-8, Cele\scl-7, Cele\scl-18, Cele\scl-9, Cele\scl-1, Cele\scl-12, Cele\scl-21, Cele\scl-3, Cele\scl-23, Cele\scl-6, Cele\scl-5, Cele\vap-2, Cele\scl-11, Cele\scl-2, Cele\scl-10, Cele\scl-17, Cele\scl-19, Cele\scl-20, Cele\scl-13, Cele\scl-15" "Xtro\crisp3, Xtro\r3hdml, Xtro\crispld2, Xtro\glipr2, Xtro\crisp2, Xtro\crisp1, Xtro\MGC108118, Xtro\pi15" "Mmus\Glipr1, Mmus\Crisp1, Mmus\R3hdml, Mmus\Crispld1, Mmus\Crisp3, Mmus\Crisp4, Mmus\Crisp2, Mmus\Glipr2, Mmus\Crispld2, Mmus\Clec18a, Mmus\Pi15, Mmus\Pi16, Mmus\Glipr1l2, Mmus\Glipr1l1" "Hsap\CLEC18C, Hsap\CLEC18A, Hsap\CLEC18B, Hsap\CRISP1, Hsap\GLIPR1L2, Hsap\CRISPLD1, Hsap\PI16, Hsap\GLIPR1L1, Hsap\GLIPR1, Hsap\GLIPR2, Hsap\CRISP2, Hsap\R3HDML, Hsap\PI15, Hsap\CRISPLD2" viable FBgn0039045 CG17119 - http://flybase.org/reports/FBgn0039045 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 L-cystine transmembrane transporter activity ; GO:0015184 | inferred from biological aspect of ancestor with PANTHER:PTN000319849 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 L-cystine transport ; GO:0015811 | inferred from biological aspect of ancestor with PANTHER:PTN000319849 lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN000319798 "CG17119, CTNS, dCTNS" "IPR005282:Lysosomal cystine transporter, IPR006603:PQ-loop repeat, IPR010916:TonB box, conserved site" CG17119 11-Aug-17 DroID_v2017_08 Drer\ctns "Scer\YCL002C, Scer\ERS1" Cele\ctns-1 Xtro\ctns Mmus\Ctns Hsap\CTNS FBgn0024804 Dbp80 Dead box protein 80 http://flybase.org/reports/FBgn0024804 "FBgn0020298, FBgn0024749, FBgn0042216, FBgn0047105, FBan0017023" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000619776 RNA splicing ; GO:0008380 | inferred from biological aspect of ancestor with PANTHER:PTN000619776 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 nuclear pore cytoplasmic filaments ; GO:0044614 | inferred from sequence or structural similarity with SGD:S000005572 catalytic step 2 spliceosome ; GO:0071013 | inferred from biological aspect of ancestor with PANTHER:PTN000619776 "Dbp80, HEL80, DBP80, BcDNA:RE44177, CG17023, hel-40, Hel80, Hel40, DmDbp80, mdcds_36124" "IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG17023 11-Aug-17 DroID_v2017_08 "Drer\zgc:193690, Drer\ddx19" Scer\DBP5 Cele\ddx-19 "Xtro\ddx19b, Xtro\ddx25" "Mmus\Ddx19b, Mmus\Ddx25, Mmus\Ddx19a" "Hsap\DDX25, Hsap\DDX19B, Hsap\DDX19A" FBgn0037683 CG18473 - http://flybase.org/reports/FBgn0037683 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR017947 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001559, InterPro:IPR017947" "catabolic process ; GO:0009056 | inferred from electronic annotation with InterPro:IPR001559, InterPro:IPR017947" cellular_component ; GO:0005575 | no biological data available "CG8125, CG18473" "IPR001559:Phosphotriesterase, IPR017947:Aryldialkylphosphatase, zinc-binding site, IPR032466:Metal-dependent hydrolase" CG18473 11-Aug-17 DroID_v2017_08 Drer\pter - - Xtro\pter Mmus\Pter Hsap\PTER viable FBgn0031069 Pmp70 Peroxisomal Membrane Protein 70 kDa http://flybase.org/reports/FBgn0031069 protein_coding_gene "ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from electronic annotation with InterPro:IPR011527, InterPro:IPR031241 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 protein homodimerization activity ; GO:0042803 | inferred from electronic annotation with InterPro:IPR031241" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 peroxisomal long-chain fatty acid import ; GO:0015910 | inferred from electronic annotation with InterPro:IPR031241 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011527 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:67 "i17, Pmp70, CG12703, PMP70" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR031241:ATP-binding cassette sub-family D member 3" CG12703 11-Aug-17 DroID_v2017_08 "Drer\abcd1, Drer\LOC101882118, Drer\LOC100537809, Drer\abcd3b, Drer\abcd3a, Drer\abcd4" "Scer\PXA1, Scer\PXA2" "Cele\pmp-2, Cele\pmp-3, Cele\pmp-1, Cele\pmp-4" "Xtro\abcd1, Xtro\abcd3" "Mmus\Abcd1, Mmus\Abcd2, Mmus\Abcd3, Mmus\Abcd4" "Hsap\ABCD2, Hsap\ABCD4, Hsap\ABCD1, Hsap\ABCD3" "viable,visible" trichogen cell FBgn0027070 CG17322 - http://flybase.org/reports/FBgn0027070 FBgn0032714 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 UDP-glycosyltransferase activity ; GO:0008194 | inferred from sequence or structural similarity with UniProtKB:P18569 xenobiotic metabolic process ; GO:0006805 | inferred from sequence or structural similarity with HGNC:12538 UDP-glucose metabolic process ; GO:0006011 | inferred from sequence or structural similarity with UniProtKB:P18569 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:12538 "LD25345, BEST:LD25345, CG17322" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG17322 11-Aug-17 DroID_v2017_08 "Drer\ugt2b5, Drer\zgc:172315, Drer\ugt2a5, Drer\ugt2a3, Drer\ugt5a1, Drer\ugt5a2, Drer\ugt5c2, Drer\ugt5a5, Drer\ugt5g1, Drer\ugt1b2, Drer\ugt2a2, Drer\ugt5b1, Drer\ugt5b3, Drer\ugt5c1, Drer\ugt5b2, Drer\ugt2a6, Drer\ugt5c3, Drer\ugt1b7, Drer\ugt5a4, Drer\ugt8, Drer\ugt5e1, Drer\ugt2b3, Drer\ugt1b5, Drer\ugt1b3, Drer\ugt5g2, Drer\ugt5f1, Drer\ugt1b4, Drer\ugt5b4, Drer\ugt5d1, Drer\ugt2b1, Drer\ugt1ab, Drer\ugt2b6, Drer\ugt5b6" Scer\ATG26 "Cele\ugt-54, Cele\ugt-56, Cele\ugt-7, Cele\ugt-47, Cele\ugt-11, Cele\ugt-59, Cele\ugt-19, Cele\ugt-44, Cele\ugt-57, Cele\ugt-51, Cele\ugt-28, Cele\ugt-27, Cele\ugt-15, Cele\ugt-35, Cele\ugt-14, Cele\ugt-39, Cele\F10D2.8, Cele\ugt-20, Cele\ugt-38, Cele\C23G10.6, Cele\ugt-25, Cele\C55H1.1, Cele\H23N18.4, Cele\ugt-52, Cele\ugt-17, Cele\ugt-2, Cele\ugt-41, Cele\ugt-8, Cele\ugt-12, Cele\ugt-5, Cele\ugt-16, Cele\ugt-43, Cele\ugt-6, Cele\ugt-48, Cele\ugt-18, Cele\ugt-60, Cele\ugt-24, Cele\ugt-23, Cele\ugt-26, Cele\ugt-10, Cele\ugt-49, Cele\ugt-50, Cele\ugt-42, Cele\C03A7.12, Cele\ugt-29, Cele\ugt-53, Cele\ugt-36, Cele\ugt-31, Cele\ugt-30, Cele\ugt-58, Cele\ugt-61, Cele\ugt-4, Cele\C03A7.13, Cele\ugt-46, Cele\ugt-55, Cele\ugt-32, Cele\ugt-45, Cele\ugt-3, Cele\ugt-33, Cele\ugt-21, Cele\K04A8.10, Cele\ugt-40, Cele\ugt-22, Cele\Y43D4A.2, Cele\ugt-13, Cele\ugt-62, Cele\ugt-37, Cele\ugt-1, Cele\ugt-34, Cele\ugt-9" "Xtro\ugt2b4, Xtro\ugt8, Xtro\ugt2a1, Xtro\ugt3a2, Xtro\ugt1a6" "Mmus\Ugt2b36, Mmus\Ugt2a3, Mmus\Ugt1a2, Mmus\Ugt2b37, Mmus\Ugt1a10, Mmus\Ugt1a7c, Mmus\Ugt3a1, Mmus\Ugt1a9, Mmus\Ugt8a, Mmus\Ugt1a5, Mmus\Ugt2b38, Mmus\Ugt2b35, Mmus\Ugt2b34, Mmus\Ugt2a1, Mmus\Ugt2a2, Mmus\Ugt2b5, Mmus\Ugt1a6b, Mmus\Ugt2b1, Mmus\Ugt3a2, Mmus\Ugt1a1" "Hsap\UGT2B15, Hsap\UGT3A1, Hsap\UGT2A3, Hsap\UGT8, Hsap\UGT1A9, Hsap\UGT2B28, Hsap\UGT1A3, Hsap\UGT1A5, Hsap\UGT1A10, Hsap\UGT1A8, Hsap\UGT1A4, Hsap\UGT1A6, Hsap\UGT1A7, Hsap\UGT2A2, Hsap\UGT2B17, Hsap\UGT2B11, Hsap\UGT2B4, Hsap\UGT1A1, Hsap\UGT2B10, Hsap\UGT2B7, Hsap\UGT3A2" viable FBgn0263930 dally division abnormally delayed http://flybase.org/reports/FBgn0263930 protein_coding_gene heparan sulfate proteoglycan binding ; GO:0043395 | inferred from electronic annotation with InterPro:IPR001863 protein binding ; GO:0005515 | inferred from physical interaction with dpp Wnt signaling pathway ; GO:0016055 | inferred from electronic annotation with InterPro:IPR031187 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | traceable author statement positive regulation of BMP signaling pathway ; GO:0030513 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype inferred from genetic interaction with wg chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype negative regulation of semaphorin-plexin signaling pathway ; GO:2001261 | inferred from genetic interaction with Sema1a motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype female germ-line stem cell asymmetric division ; GO:0048132 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | non-traceable author statement wing disc development ; GO:0035220 | inferred from mutant phenotype regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype decapentaplegic signaling pathway ; GO:0008101 | non-traceable author statement regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype decapentaplegic signaling pathway ; GO:0008101 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR001863 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001863 perivitelline space ; GO:0098595 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay "dally, CG4974, Dally, l(3)SG18, CT15952, gem, clone 1.63, l(3)06464, anon-EST:Liang-1.63" "IPR001863:Glypican, IPR031187:Division abnormally delayed protein" CG4974 11-Aug-17 DroID_v2017_08 "Drer\gpc6a, Drer\gpc6b, Drer\gpc1b, Drer\gpc4, Drer\zgc:174972, Drer\gpc3, Drer\gpc5a, Drer\gpc5c, Drer\gpc2, Drer\gpc1a, Drer\gpc5b" - Cele\gpn-1 "Xtro\gpc2, Xtro\gpc5, Xtro\gpc1, Xtro\gpc4" "Mmus\Gpc5, Mmus\Gpc6, Mmus\Gpc3, Mmus\Gpc1, Mmus\Gpc4, Mmus\Gpc2" "Hsap\GPC5, Hsap\GPC6, Hsap\GPC4, Hsap\GPC1, Hsap\GPC2, Hsap\GPC3" " larval stage | third instar , embryonic stage | stage 8 , embryonic stage , embryonic stage | early " " larval inner optic anlage

, eye-antennal disc

,

segment polarity , ventral thoracic disc

, dorsal mesothoracic disc

,

ubiquitous , lamina anlage

, ectoderm | restricted

" FBgn0039407 CG14544 - http://flybase.org/reports/FBgn0039407 protein_coding_gene tRNA (adenine-N1-)-methyltransferase activity ; GO:0016429 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000253097 tRNA methylation ; GO:0030488 | inferred from electronic annotation with InterPro:IPR014816 lateral inhibition ; GO:0046331 | inferred from mutant phenotype tRNA (m1A) methyltransferase complex ; GO:0031515 | inferred from biological aspect of ancestor with PANTHER:PTN000253097 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000253099 CG14544 "IPR014816:tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG14544 11-Aug-17 DroID_v2017_08 Drer\trmt61a Scer\GCD14 Cele\W02A11.1 Xtro\trmt61a Mmus\Trmt61a "Hsap\TRMT61B, Hsap\TRMT61A" "lethal,viable,visible" "embryonic/larval brain,chaeta,trichogen cell" FBgn0035231 Pcyt2 Phosphocholine cytidylyltransferase 2 http://flybase.org/reports/FBgn0035231 protein_coding_gene choline-phosphate cytidylyltransferase activity ; GO:0004105 | inferred from direct assay biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004821 cytoplasm ; GO:0005737 | inferred from direct assay "CCT2, CT1187, cct2, CG18330, Cct2, Pcyt2" "IPR004821:Cytidyltransferase-like domain, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG18330 11-Aug-17 DroID_v2017_08 "Drer\pcyt1ab, Drer\pcyt1aa, Drer\pcyt1ba, Drer\pcyt1bb" Scer\PCT1 "Cele\Y18H1A.11, Cele\pcyt-1" "Xtro\pcyt1a, Xtro\pcyt1b" "Mmus\Pcyt1b, Mmus\Pcyt1a" "Hsap\PCYT1A, Hsap\PCYT1B" FBgn0264815 Pde1c Phosphodiesterase 1c http://flybase.org/reports/FBgn0264815 protein_coding_gene "calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity ; GO:0048101 | inferred from direct assay 3',5'-cyclic-GMP phosphodiesterase activity ; GO:0047555 | inferred from direct assay calmodulin binding ; GO:0005516 | inferred from sequence model 3',5'-cyclic-AMP phosphodiesterase activity ; GO:0004115 | inferred from direct assay" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002073 cGMP metabolic process ; GO:0046068 | inferred from direct assay cAMP metabolic process ; GO:0046058 | inferred from direct assay male mating behavior ; GO:0060179 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Pde1c, CG31758, CG42325, PDE1C, CG14940, PDE1c, CG14943, CG14944, CG31757, CG14942, CG44007, mdcds_1440" "IPR002073:3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR013706:3'5'-cyclic nucleotide phosphodiesterase N-terminal, IPR023174:3'5'-cyclic nucleotide phosphodiesterase, conserved site, IPR023088:3'5'-cyclic nucleotide phosphodiesterase, IPR003607:HD/PDEase domain" CG44007 11-Aug-17 DroID_v2017_08 "Drer\pde1a, Drer\pde1cb" Scer\PDE2 Cele\pde-1 "Xtro\pde1a, Xtro\pde1c, Xtro\pde1b" "Mmus\Pde1b, Mmus\Pde1c, Mmus\Pde1a" "Hsap\PDE1A, Hsap\PDE1B, Hsap\PDE1C" DRSC19489 E 1.426747453 0.815303626 3.050399095 -0.449258615 FBgn0085409 smal smoke alarm http://flybase.org/reports/FBgn0085409 protein_coding_gene collagen binding ; GO:0005518 | inferred from sequence or structural similarity with HGNC:2731 oligosaccharide binding ; GO:0070492 | inferred from biological aspect of ancestor with PANTHER:PTN001564933 peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from sequence or structural similarity with HGNC:2731 detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype collagen-activated tyrosine kinase receptor signaling pathway ; GO:0038063 | inferred from sequence or structural similarity with HGNC:2731 negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype focal adhesion ; GO:0005925 | inferred from sequence or structural similarity with HGNC:2731 "CG13988, CG15813, CG13987, CG13986, anon-WO0073329.6, CG31640, CG34380, smal" "IPR008979:Galactose-binding domain-like, IPR000421:Coagulation factor 5/8 C-terminal domain" CG34380 11-Aug-17 DroID_v2017_08 "Drer\ddr2b, Drer\ddr2l, Drer\ddr1, Drer\ddr2a" - "Cele\ddr-1, Cele\ddr-2" "Xtro\ddr2, Xtro\ddr1" "Mmus\Ddr1, Mmus\Ddr2" "Hsap\DDR2, Hsap\DDR1" DRSC02318 EK -1.486106275 -0.624803701 -1.756776163 -1.206051193 1.510738365 -0.133466372 FBgn0035555 CG13720 - http://flybase.org/reports/FBgn0035555 protein_coding_gene - - - CG13720 - CG13720 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC08329 IEK 0.37935914 -1.722271873 -1.154269315 2.435433502 0.514395707 1.535596861 FBgn0036935 CG14186 - http://flybase.org/reports/FBgn0036935 protein_coding_gene - - - CG14186 IPR029409:Transmembrane protein 237 CG14186 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC10185 K -0.542647093 0.62756085 -0.444681014 -0.140772232 -1.562416446 -0.454003737 FBgn0033448 hebe hebe http://flybase.org/reports/FBgn0033448 protein_coding_gene - determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype - "hebe, CG1623" - CG1623 11-Aug-17 DroID_v2017_08 - - - - - - "viable,long lived" DRSC21614 E 0.170522281 1.014179146 1.663291358 0.450142322 0.433376746 1.16239998 FBgn0036046 Ilp2 Insulin-like peptide 2 http://flybase.org/reports/FBgn0036046 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 locomotor rhythm ; GO:0045475 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | traceable author statement carbohydrate utilization ; GO:0009758 | inferred from mutant phenotype cellular response to glucose stimulus ; GO:0071333 | inferred from expression pattern larval feeding behavior ; GO:0030536 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype female mating behavior ; GO:0060180 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement regulation of organ growth ; GO:0046620 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 inferred from genetic interaction with InR regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from biological aspect of ancestor with PANTHER:PTN001414741 negative regulation of feeding behavior ; GO:2000252 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | NOT inferred from mutant phenotype growth ; GO:0040007 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype regulation of growth rate ; GO:0040009 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype extracellular region ; GO:0005576 | non-traceable author statement extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "Ilp, Dilp2, dILP-2, dilp2, DILP2, DILP, dilp, ILP2, dilp-2, Dilp, dILP2, CG8167, Dilp 2, IRP, Ilp2, Dilp-2, ilp2, dIlp2, Ilp-2, DILP-2, dipl2" "IPR016179:Insulin-like, IPR022352:Insulin family, IPR022353:Insulin, conserved site" CG8167 11-Aug-17 DroID_v2017_08 - - Cele\ins-1 - - - " larval stage , embryonic stage | stage 12-16 , larval stage | third instar " " larval brain | restricted

, mesoderm

, imaginal disc

ubiquitous , embryonic/larval salivary gland

ubiquitous , embryonic/larval midgut

, larval brain | restricted

anterior & medial " "large body,visible,increased cell number,increased cell size,lethal,chemical resistant,stress response defective,short lived,nutrition conditional,size defective,feeding behavior defective,heat sensitive,viable,developmental rate defective,long lived,mating defective,small body" wing DRSC29688 K 1.026157944 -0.523796378 -0.028547484 0.166272508 -0.633506825 1.772251887 FBgn0030737 CG9914 - http://flybase.org/reports/FBgn0030737 protein_coding_gene "3-hydroxyacyl-CoA dehydrogenase activity ; GO:0003857 | inferred from electronic annotation with InterPro:IPR006108, InterPro:IPR006176, InterPro:IPR006180, InterPro:IPR022694 NAD+ binding ; GO:0070403 | inferred from electronic annotation with InterPro:IPR022694" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006108, InterPro:IPR006176, InterPro:IPR006180, InterPro:IPR008927, InterPro:IPR013328, InterPro:IPR022694 fatty acid metabolic process ; GO:0006631 | inferred from electronic annotation with InterPro:IPR006108, InterPro:IPR006176, InterPro:IPR006180, InterPro:IPR022694" - CG9914 "IPR006108:3-hydroxyacyl-CoA dehydrogenase, C-terminal, IPR006176:3-hydroxyacyl-CoA dehydrogenase, NAD binding, IPR006180:3-hydroxyacyl-CoA dehydrogenase, conserved site, IPR008927:6-phosphogluconate dehydrogenase C-terminal domain-like, IPR016040:NAD(P)-binding domain, IPR022694:3-hydroxyacyl-CoA dehydrogenase, IPR013328:6-phosphogluconate dehydrogenase, domain 2" CG9914 11-Aug-17 DroID_v2017_08 Drer\cryl1 - Cele\Y71F9B.9 Xtro\cryl1 Mmus\Cryl1 Hsap\CRYL1 viable DRSC20216 K 0.407541671 0.68685055 -0.574899697 -0.1670755 1.818331994 0.563133281 FBgn0261963 mid midline http://flybase.org/reports/FBgn0261963 protein_coding_gene "RNA polymerase II transcription corepressor binding ; GO:0001226 | inferred from physical interaction with gro RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001227 | inferred from direct assay inferred from mutant phenotype" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay heart process ; GO:0003015 | inferred from direct assay regulation of cell fate specification ; GO:0042659 | inferred from mutant phenotype regulation of cell fate specification ; GO:0042659 | inferred from genetic interaction with H15 neuron fate specification ; GO:0048665 | inferred from mutant phenotype axonogenesis ; GO:0007409 | non-traceable author statement neuroblast development ; GO:0014019 | inferred from mutant phenotype leg disc pattern formation ; GO:0035223 | inferred from genetic interaction with H15 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype fasciculation of motor neuron axon ; GO:0097156 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype cardioblast cell fate commitment ; GO:0042684 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype inferred from genetic interaction with HGTX central nervous system development ; GO:0007417 | inferred from mutant phenotype inferred from genetic interaction with HGTX chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype ganglion mother cell fate determination ; GO:0007402 | inferred from mutant phenotype neuroblast fate specification ; GO:0014018 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype regulation of nervous system development ; GO:0051960 | inferred from mutant phenotype regulation of cardioblast differentiation ; GO:0051890 | inferred from mutant phenotype "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR018186" "CG6634, mid, nmr2, H15r/nmr2, H15r, Mid(H15), los, extra, TBX20, Mid" "IPR018186:Transcription factor, T-box, conserved site, IPR001699:Transcription factor, T-box, IPR008967:p53-like transcription factor, DNA-binding" CG6634 11-Aug-17 DroID_v2017_08 "Drer\tbx18, Drer\eomesb, Drer\tbx3b, Drer\tbx1, Drer\eomesa, Drer\tbx21, Drer\tbx2b, Drer\tbx20, Drer\tbx16, Drer\tbr1a, Drer\tbx22, Drer\tbx6, Drer\mgaa, Drer\tbx2a, Drer\tbx5a, Drer\grap2b, Drer\tbx15, Drer\tbr1b, Drer\tbx5b" - "Cele\mab-9, Cele\mls-1, Cele\tbx-43, Cele\tbx-2, Cele\tbx-7" "Xtro\tbx22, Xtro\vegt, Xtro\tbx1, Xtro\tbx3, Xtro\tbx18, Xtro\mga, Xtro\tbx4, Xtro\tbx2, Xtro\tbx20, Xtro\tbx5" "Mmus\Tbx6, Mmus\Tbx21, Mmus\Tbr1, Mmus\Tbx4, Mmus\Tbx20, Mmus\Tbx18, Mmus\Tbx3, Mmus\Eomes, Mmus\Tbx10, Mmus\Tbx22, Mmus\Tbx2, Mmus\Tbx15, Mmus\Tbx1, Mmus\Mga, Mmus\Tbx5" "Hsap\TBX2, Hsap\TBR1, Hsap\MGA, Hsap\TBX4, Hsap\TBX22, Hsap\TBX21, Hsap\TBX3, Hsap\EOMES, Hsap\TBX15, Hsap\TBX18, Hsap\TBX20, Hsap\TBX5, Hsap\TBX1, Hsap\TBX6, Hsap\TBX10" " embryonic stage | stage 5 , embryonic stage | stage 14-15 , embryonic stage | stage 15 , embryonic stage | stage 12 , larval stage | third instar " " organism | segment polarity

, embryonic heart

, embryonic brain

, embryonic ventral nervous system

, ventral thoracic disc | ventral & proximal | restricted

" DRSC02977 E 0.654743822 -0.050344335 1.523325418 0.391926409 -0.263649577 0.307618552 FBgn0053904 His2B:CG33904 His2B:CG33904 http://flybase.org/reports/FBgn0053904 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33904, His2B:CG33904" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33904 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113a14.28, Drer\si:dkey-108k21.11, Drer\si:ch211-113a14.29, Drer\si:ch1073-159d7.5, Drer\si:dkey-23a13.1, Drer\si:ch73-368j24.8, Drer\si:ch211-113a14.11, Drer\LOC100329290, Drer\hist1h2ba, Drer\zgc:173585, Drer\zgc:114046, Drer\si:dkey-108k21.27, Drer\si:dkey-23a13.5, Drer\ano9a, Drer\LOC100329560, Drer\si:ch1073-159d7.13, Drer\zgc:92591, Drer\si:ch73-36p18.3, Drer\si:dkey-261m9.19, Drer\zgc:194989, Drer\hist2h2l, Drer\zgc:173587, Drer\si:dkey-23a13.16, Drer\LOC100334559, Drer\si:ch1073-153i20.3, Drer\LOC100334869, Drer\si:dkey-261m9.6" "Scer\HTB2, Scer\HTB1" "Cele\his-15, Cele\his-8, Cele\his-29, Cele\his-54, Cele\his-48, Cele\his-4, Cele\his-52, Cele\his-22, Cele\his-41, Cele\his-20, Cele\his-62, Cele\his-44, Cele\his-58, Cele\his-34, Cele\his-11, Cele\his-39, Cele\his-66" "Xtro\LOC100485134, Xtro\LOC100487485, Xtro\hist1h2bm, Xtro\LOC100497915, Xtro\LOC100486150, Xtro\LOC100496181, Xtro\LOC101734494, Xtro\LOC100485294, Xtro\LOC101733489, Xtro\LOC100498553, Xtro\LOC100498329, Xtro\LOC101733171, Xtro\LOC100495415, Xtro\hist2h2be, Xtro\LOC101735218, Xtro\LOC100492632, Xtro\LOC100497082, Xtro\LOC101731959, Xtro\LOC100496445, Xtro\LOC101731852, Xtro\hist1h2bj, Xtro\LOC100498647, Xtro\hist1h2bk, Xtro\LOC100486870, Xtro\LOC100498072, Xtro\LOC101731067, Xtro\LOC101735164, Xtro\LOC100495041, Xtro\LOC101734862, Xtro\LOC101733828, Xtro\LOC100495578, Xtro\LOC101730940, Xtro\LOC100496436, Xtro\LOC100495396" "Mmus\Hist1h2be, Mmus\Hist1h2br, Mmus\Hist1h2bc, Mmus\Hist1h2bj, Mmus\Hist2h2bb, Mmus\Hist1h2bf, Mmus\Hist1h2bk, Mmus\Hist1h2bq, Mmus\H2bfm, Mmus\Hist1h2bb, Mmus\Hist1h2bm, Mmus\Hist3h2ba, Mmus\Hist1h2bl, Mmus\Hist2h2be, Mmus\Hist1h2bp, Mmus\Hist1h2bn, Mmus\Hist1h2ba, Mmus\Hist1h2bh, Mmus\1700024P04Rik, Mmus\Hist1h2bg" "Hsap\HIST1H2BG, Hsap\HIST1H2BF, Hsap\HIST1H2BA, Hsap\HIST1H2BE, Hsap\HIST3H2BB, Hsap\HIST1H2BN, Hsap\HIST2H2BF, Hsap\H2BFWT, Hsap\HIST1H2BB, Hsap\HIST1H2BJ, Hsap\HIST2H2BE, Hsap\HIST1H2BC, Hsap\HIST1H2BI, Hsap\H2BFM, Hsap\HIST1H2BO, Hsap\HIST1H2BK, Hsap\HIST1H2BM, Hsap\HIST1H2BD, Hsap\HIST1H2BH, Hsap\HIST1H2BL" FBgn0263121 Prosalpha1 Proteasome alpha1 subunit http://flybase.org/reports/FBgn0263121 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426 proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay" "CG18495, Prosalpha6, Prosalpha1, 18495, PSA6_DROME, prosalpha1, l(2)SH2342, l(2)SH2 2342, Alpha-1, alpha1, prosalpha6, alpha-1" "IPR029055:Nucleophile aminohydrolases, N-terminal, IPR034642:Proteasome subunit alpha6, IPR023332:Proteasome alpha-type subunit, IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta" CG18495 11-Aug-17 DroID_v2017_08 "Drer\psma6l, Drer\psma6a, Drer\psma6b" Scer\SCL1 Cele\pas-1 Xtro\psma6 Mmus\Psma6 Hsap\PSMA6 "neuroanatomy defective,lethal,recessive" rhabdomere of eye photoreceptor cell DRSC07515 IEK -2.335959773 -2.87074977 -1.812772388 -1.150262632 1.591377384 1.378424082 FBgn0033226 CG1882 - http://flybase.org/reports/FBgn0033226 protein_coding_gene epoxide hydrolase activity ; GO:0004301 | inferred from sequence or structural similarity with HGNC:3402 carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay - peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:3402 lipid particle ; GO:0005811 | inferred from direct assay CG1882 "IPR000073:Alpha/beta hydrolase fold-1, IPR000639:Epoxide hydrolase-like, IPR029058:Alpha/Beta hydrolase fold" CG1882 11-Aug-17 DroID_v2017_08 "Drer\abhd4, Drer\abhd5a, Drer\LOC100329433, Drer\LOC570571" "Scer\ECM18, Scer\ICT1, Scer\CLD1" "Cele\C31H5.1, Cele\abhd-5.1, Cele\F35H12.5, Cele\ceeh-1, Cele\abhd-5.2, Cele\lid-1" "Xtro\abhd4, Xtro\abhd5" "Mmus\Abhd4, Mmus\Abhd5, Mmus\Ephx4" "Hsap\ABHD4, Hsap\ABHD5, Hsap\EPHX3" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0035771 Sec63 Secretory 63 http://flybase.org/reports/FBgn0035771 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from electronic annotation with InterPro:IPR027137 "posttranslational protein targeting to membrane, translocation ; GO:0031204 | inferred from electronic annotation with InterPro:IPR027137" fusome ; GO:0045169 | inferred from direct assay "peg, CG8583, anon-WO0118547.333, sec63, Sec63" "IPR018253:DnaJ domain, conserved site, IPR001623:DnaJ domain, IPR004179:Sec63 domain, IPR014756:Immunoglobulin E-set, IPR027137:Translocation protein Sec63, IPR000008:C2 domain" CG8583 11-Aug-17 DroID_v2017_08 Drer\sec63 Scer\SEC63 Cele\dnj-29 Xtro\sec63 Mmus\Sec63 Hsap\SEC63 "lethal,viable" FBgn0034091 mrj mrj http://flybase.org/reports/FBgn0034091 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with ECOGENE:EG10240 protein folding ; GO:0006457 | inferred from sequence or structural similarity with ECOGENE:EG10240 protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P08622 cellular_component ; GO:0005575 | no biological data available "CG8448, dMRJ, dmrj, mrj, MRJ, mrjA" "IPR018253:DnaJ domain, conserved site, IPR001623:DnaJ domain" CG8448 11-Aug-17 DroID_v2017_08 "Drer\dnajb12b, Drer\dnajb5, Drer\dnajb12a, Drer\dnajb6b, Drer\dnajb4, Drer\dnajc22, Drer\dnajb9a, Drer\dnajb14, Drer\dnajb1a, Drer\dnajc18, Drer\dnajb2, Drer\dnajb6a, Drer\dnajb1b" "Scer\DJP1, Scer\ERJ5, Scer\SCJ1, Scer\JJJ1, Scer\APJ1, Scer\HLJ1, Scer\SIS1" "Cele\dnj-24, Cele\dnj-26" "Xtro\dnajb4, Xtro\dnajc18, Xtro\dnajb2, Xtro\dnajb6, Xtro\dnajb14, Xtro\dnajb9, Xtro\dnajb13, Xtro\dnajb5, Xtro\dnajc22, Xtro\dnajb1, Xtro\dnajb12" "Mmus\Dnajb7, Mmus\Dnajc21, Mmus\Dnajb5, Mmus\Dnajb14, Mmus\Dnajc22, Mmus\Dnajb13, Mmus\Dnajb1, Mmus\Dnajb8, Mmus\4930503B20Rik, Mmus\Dnajb3, Mmus\Dnajc18, Mmus\Dnajb9, Mmus\Dnajb4, Mmus\Dnajb12, Mmus\Dnajb2, Mmus\Dnajb6" "Hsap\DNAJB14, Hsap\DNAJC18, Hsap\DNAJB7, Hsap\DNAJB9, Hsap\DNAJB3, Hsap\DNAJB12, Hsap\DNAJB6, Hsap\TMEM135, Hsap\DNAJC22, Hsap\DNAJB8, Hsap\DNAJB1, Hsap\DNAJB13, Hsap\DNAJB2, Hsap\DNAJB4, Hsap\DNAJB5" "partially lethal - majority die,visible" mesothoracic tergum FBgn0030863 CG8188 - http://flybase.org/reports/FBgn0030863 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:17895 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630752 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:17895 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype exit from mitosis ; GO:0010458 | inferred from mutant phenotype anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000630752 "Ubc, CG8188, Ube2S" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG8188 11-Aug-17 DroID_v2017_08 Drer\ube2s Scer\RAD6 - Xtro\ube2s Mmus\Ube2s Hsap\UBE2S "viable,fertile" FBgn0033100 CG3420 - http://flybase.org/reports/FBgn0033100 protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR006622, InterPro:IPR018967" - "intracellular membrane-bounded organelle ; GO:0043231 | inferred from electronic annotation with InterPro:IPR006622, InterPro:IPR018967" "BcDNA:RE40412, CG3420" "IPR018967:Iron sulphur-containing domain, CDGSH-type" CG3420 11-Aug-17 DroID_v2017_08 - - "Cele\cisd-3.2, Cele\cisd-3.1" Xtro\cisd3 Mmus\Cisd3 Hsap\CISD3 "partially lethal - majority die,some die during pupal stage" FBgn0085419 Rgk2 "Rad, Gem/Kir family member 2" http://flybase.org/reports/FBgn0085419 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from sequence model GTPase activity ; GO:0003924 | inferred from sequence model" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 negative regulation of voltage-gated calcium channel activity ; GO:1901386 | inferred from direct assay small GTPase mediated signal transduction ; GO:0007264 | inferred from sequence model membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cytoplasmic side of plasma membrane ; GO:0009898 | inferred from sequence model "CG34390, CG15069, Rgk2, CG30119, RGK2" "IPR001806:Small GTPase superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG34390 11-Aug-17 DroID_v2017_08 "Drer\ralab, Drer\rras, Drer\zgc:153845, Drer\zgc:114118, Drer\diras1a, Drer\rem1, Drer\rras2, Drer\rerglb, Drer\rasl12, Drer\zgc:110699, Drer\nras, Drer\si:dkey-27j5.5, Drer\rheb, Drer\hrasb, Drer\rap1ab, Drer\rem2, Drer\rasl11a, Drer\rap2ab, Drer\rap1aa, Drer\rasd1, Drer\rit1, Drer\rsg1, Drer\zgc:171704, Drer\ralbb, Drer\kras, Drer\rasl11b, Drer\rhebl1, Drer\diras1b, Drer\rasl10a, Drer\rap2b, Drer\gem, Drer\si:ch73-116o1.2, Drer\ralba, Drer\mras, Drer\ralaa, Drer\zgc:152698, Drer\rap2c, Drer\zgc:64022, Drer\LOC100332969, Drer\rrad, Drer\hrasa, Drer\rergla, Drer\si:dkeyp-59c12.1, Drer\diras2" "Scer\RAS2, Scer\RSR1, Scer\RHB1, Scer\RAS1" "Cele\Y52B11A.4, Cele\W04C9.5, Cele\F20D6.8, Cele\rsef-1" "Xtro\rergl, Xtro\diras1, Xtro\diras3, Xtro\rap2a, Xtro\rit1, Xtro\LOC733456, Xtro\gem, Xtro\hras, Xtro\rasl11b, Xtro\rsg1, Xtro\rerg, Xtro\rap2b, Xtro\diras2, Xtro\rheb, Xtro\nras, Xtro\rap1b, Xtro\ralb, Xtro\rap1a, Xtro\rasl10a, Xtro\rrad, Xtro\kras, Xtro\rem2, Xtro\rasd1, Xtro\ras-dva, Xtro\rap2c, Xtro\rhebl1, Xtro\rasd2, Xtro\rem1, Xtro\rala" "Mmus\Rsg1, Mmus\Rasl11b, Mmus\Rap1a, Mmus\Rasl10b, Mmus\Gem, Mmus\Rem1, Mmus\Rit1, Mmus\Eras, Mmus\Rit2, Mmus\Gm266, Mmus\Diras1, Mmus\Rala, Mmus\Rasl12, Mmus\Hras, Mmus\Ralb, Mmus\Rheb, Mmus\Rhebl1, Mmus\Rergl, Mmus\Rasl11a, Mmus\Rap2a, Mmus\Rras, Mmus\Rasd2, Mmus\Rras2, Mmus\Rerg, Mmus\Rasl10a, Mmus\Rap2b, Mmus\Diras2, Mmus\Rap1b, Mmus\Nras, Mmus\Kras, Mmus\Rem2, Mmus\Rap2c, Mmus\Mras, Mmus\Rrad, Mmus\Rasd1" "Hsap\RIT2, Hsap\MRAS, Hsap\DIRAS2, Hsap\RIT1, Hsap\RALB, Hsap\RASL11A, Hsap\RAP1A, Hsap\GEM, Hsap\RAB44, Hsap\RERGL, Hsap\RHEB, Hsap\RASD2, Hsap\ERAS, Hsap\RAP2A, Hsap\RASL12, Hsap\HRAS, Hsap\RAP2C, Hsap\RRAD, Hsap\RAP1B, Hsap\RASL10B, Hsap\REM2, Hsap\DIRAS1, Hsap\REM1, Hsap\RRAS, Hsap\RAP2B, Hsap\NRAS, Hsap\RASL10A, Hsap\DIRAS3, Hsap\RASD1, Hsap\RSG1, Hsap\RERG, Hsap\RRAS2, Hsap\RHEBL1, Hsap\RASL11B, Hsap\KRAS, Hsap\RALA" viable FBgn0033883 CG16935 - http://flybase.org/reports/FBgn0033883 protein_coding_gene trans-2-enoyl-CoA reductase (NADPH) activity ; GO:0019166 | inferred from sequence or structural similarity with UniProtKB:Q9BV79 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR013149 fatty acid metabolic process ; GO:0006631 | inferred from sequence or structural similarity with UniProtKB:Q9BV79" microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9BV79 "DM_7303260, CG16935" "IPR011032:GroES-like, IPR013149:Alcohol dehydrogenase, C-terminal, IPR016040:NAD(P)-binding domain, IPR020843:Polyketide synthase, enoylreductase domain, IPR013154:Alcohol dehydrogenase, N-terminal" CG16935 11-Aug-17 DroID_v2017_08 "Drer\LOC101884755, Drer\mecr, Drer\cryzl1" "Scer\ETR1, Scer\AST1" "Cele\mecr-1, Cele\Y48A6B.9" "Xtro\mecr, Xtro\LOC100170432, Xtro\cryzl1" "Mmus\Cryzl1, Mmus\Mecr" "Hsap\MECR, Hsap\CRYZL1" FBgn0039631 Sirt7 Sirtuin 7 http://flybase.org/reports/FBgn0039631 protein_coding_gene NAD+ binding ; GO:0070403 | inferred from electronic annotation with InterPro:IPR003000 - nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:14935 "CG11305, dmSRT409, dSIRT7, D.mel5, Sirt7, SIRT7" "IPR003000:Sirtuin family, IPR029035:DHS-like NAD/FAD-binding domain, IPR026590:Sirtuin family, catalytic core domain" CG11305 11-Aug-17 DroID_v2017_08 "Drer\sirt6, Drer\sirt7" - Cele\sir-2.4 "Xtro\sirt7, Xtro\sirt6" "Mmus\Sirt6, Mmus\Sirt7" "Hsap\SIRT7, Hsap\SIRT6" "viable,fertile" FBgn0016685 Nlp Nucleoplasmin http://flybase.org/reports/FBgn0016685 FBgn0016133 protein_coding_gene histone binding ; GO:0042393 | inferred from direct assay histone binding ; GO:0042393 | traceable author statement sperm chromatin decondensation ; GO:0035041 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay polytene chromosome interband ; GO:0005705 | colocalizes_with inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "dNLP, dNLP-S, CRP1, p22, Crp1, CG7917, Nlp, NLP, nlp, dCAF-4" "IPR004301:Nucleoplasmin family, IPR024057:Nucleoplasmin core domain" CG7917 11-Aug-17 DroID_v2017_08 "Drer\npm2a, Drer\npm3, Drer\npm2b, Drer\npm1b, Drer\npm1a" - - "Xtro\LOC100495408, Xtro\npm3, Xtro\npm1, Xtro\npm2" "Mmus\Npm2, Mmus\Npm1, Mmus\Npm3" "Hsap\NPM1, Hsap\NPM2, Hsap\NPM3" embryonic stage -- adult stage embryonic stage -- adult stage viable FBgn0025936 Eph Eph receptor tyrosine kinase http://flybase.org/reports/FBgn0025936 "FBgn0015726, FBgn0023093" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001426, InterPro:IPR016257, InterPro:IPR017441 transmembrane-ephrin receptor activity ; GO:0005005 | inferred from sequence or structural similarity with UniProtKB:P54762 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement" protein autophosphorylation ; GO:0046777 | inferred from sequence or structural similarity with UniProtKB:P54762 ephrin receptor signaling pathway ; GO:0048013 | inferred from sequence or structural similarity with UniProtKB:P54762 mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with UniProtKB:P54762 "Eph, eph, Dek, Deph, DEK, CT3831, CG1511, dek, Dek7, RPTK Dek7, Ek7, lincRNA.923" "IPR000719:Protein kinase domain, IPR001090:Ephrin receptor ligand binding domain, IPR001660:Sterile alpha motif domain, IPR003961:Fibronectin type III, IPR008266:Tyrosine-protein kinase, active site, IPR008979:Galactose-binding domain-like, IPR011009:Protein kinase-like domain, IPR001426:Tyrosine-protein kinase, receptor class V, conserved site, IPR016257:Ephrin receptor type-A /type-B, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR027936:Ephrin receptor, transmembrane domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR009030:Growth factor receptor cysteine-rich domain, IPR013783:Immunoglobulin-like fold, IPR013761:Sterile alpha motif/pointed domain, IPR011641:Tyrosine-protein kinase ephrin type A/B receptor-like" CG1511 11-Aug-17 DroID_v2017_08 "Drer\ephb2a, Drer\epha4a, Drer\ephb6, Drer\epha7, Drer\epha2b, Drer\epha5, Drer\epha3, Drer\ephb4a, Drer\ephb3a, Drer\ephb1, Drer\LOC100329589, Drer\ephb4b, Drer\epha4l, Drer\epha2a, Drer\ephb3, Drer\tek, Drer\epha8, Drer\epha6, Drer\epha4b, Drer\ek1, Drer\ephb2b" "Scer\KIN1, Scer\SCH9" "Cele\vab-1, Cele\ddr-2, Cele\F09A5.2" "Xtro\epha3, Xtro\ephb4, Xtro\epha6, Xtro\epha2, Xtro\ephb1, Xtro\ephb3, Xtro\epha7, Xtro\epha8, Xtro\epha4, Xtro\epha10" "Mmus\Epha1, Mmus\Ephb6, Mmus\Epha10, Mmus\Epha8, Mmus\Epha7, Mmus\Axl, Mmus\Ephb4, Mmus\Insrr, Mmus\Epha4, Mmus\Tyro3, Mmus\Epha2, Mmus\Ephb2, Mmus\Epha6, Mmus\Insr, Mmus\Ephb1, Mmus\Epha5, Mmus\Epha3, Mmus\Ephb3" "Hsap\INSRR, Hsap\EPHB3, Hsap\EPHA1, Hsap\AXL, Hsap\EPHA5, Hsap\EPHA4, Hsap\EPHB1, Hsap\EPHA6, Hsap\EPHA7, Hsap\EPHB4, Hsap\EPHA10, Hsap\EPHB2, Hsap\EPHA3, Hsap\EPHB6, Hsap\TYRO3, Hsap\INSR, Hsap\EPHA8, Hsap\EPHA2" "viable,recessive,fertile,neuroanatomy defective,immune response defective,partially lethal - majority die,female semi-sterile,learning defective,visible,some die during pupal stage" "vertical lobe of adult mushroom body,somatic clone,medial lobe of adult mushroom body,medulla neuropil,lobula,cell body rind of medulla,cell body rind of lobula plate,photoreceptor & axon,commissure,longitudinal connective,embryonic/larval neuron,photoreceptor cell & axoney.PH,embryonic/larval optic lobe,photoreceptor cell R7 & axon | somatic clone‘±Tub84B.PP,photoreceptor cell R8 & axon | somatic clone‘±Tub84B.PP,photoreceptor cell & axonbi-md653,fascicle" FBgn0034606 ASPP "Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein" http://flybase.org/reports/FBgn0034606 protein_coding_gene protein tyrosine kinase activator activity ; GO:0030296 | inferred from direct assay positive regulation of protein tyrosine kinase activity ; GO:0061098 | inferred from genetic interaction with Csk adherens junction ; GO:0005912 | inferred from direct assay "dASPP, CG18375, ASPP" "IPR001452:SH3 domain, IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG18375 11-Aug-17 DroID_v2017_08 "Drer\ppp1r13ba, Drer\tp53bp2a, Drer\tp53bp2b, Drer\ppp1r13l, Drer\ppp1r13bb" - Cele\ape-1 "Xtro\tp53bp2, Xtro\ppp1r13l, Xtro\ppp1r13b" "Mmus\Trp53bp2, Mmus\Ppp1r13l, Mmus\Ppp1r13b" "Hsap\PPP1R13B, Hsap\PPP1R13L, Hsap\TP53BP2" "visible,increased cell number,partially lethal - majority die,some die during pupal stage" "eye,interommatidial bristle,ommatidium,wing" FBgn0000567 Eip74EF Ecdysone-induced protein 74EF http://flybase.org/reports/FBgn0000567 "FBgn0011459, FBgn0026806, FBgn0036739, FBgn0052180" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" "regulation of development, heterochronic ; GO:0040034 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype oogenesis ; GO:0048477 | non-traceable author statement cell death ; GO:0008219 | traceable author statement salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "E74, E74B, E74A, E74A/B, Eip74E, CG6273, ECIP, e74, 3.3, E74-B, E-74, mE74, l(3)neo24, l(3)24, CG6285, CG32180, Eip74EF, eip74ef, Eip74, Eip74 A, Eip74A, 74EF, eip74EF, e74B" "IPR000418:Ets domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG32180 11-Aug-17 DroID_v2017_08 "Drer\ehf, Drer\elf2a, Drer\etv7, Drer\ef1, Drer\elf2b" - "Cele\ets-7, Cele\elf-1, Cele\F19F10.1" "Xtro\etv6, Xtro\ehf, Xtro\elf2, Xtro\elf1" "Mmus\Ehf, Mmus\Elf1, Mmus\Elf2, Mmus\Elf4, Mmus\Elf3, Mmus\Elf5, Mmus\Etv6" "Hsap\EHF, Hsap\ELF3, Hsap\ELF4, Hsap\ETV7, Hsap\ETV6, Hsap\ELF1, Hsap\ELF5, Hsap\ELF2" " prepupal stage , prepupal stage | stage P4 , prepupal stage | stage P1-3 " organism

"lethal,recessive,lethal - all die before end of P-stage,some die during P-stage,decreased cell death,some die during pharate adult stage,viable,short lived,heat sensitive,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage" "adult epidermis,embryonic/larval salivary gland,salivary gland,embryonic/larval midgut,adult brain,heat sensitive,larva,cuticle,air bubble,anterior pupal spiracle,procephalic segment" DRSC11160 EK -0.828445662 1.013755812 -1.067100211 1.896715567 1.612593245 1.384300016 FBgn0031462 CG2964 - http://flybase.org/reports/FBgn0031462 protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 potassium ion binding ; GO:0030955 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 pyruvate kinase activity ; GO:0004743 | inferred from sequence or structural similarity with SGD:S000000036 pyruvate kinase activity ; GO:0004743 | inferred from biological aspect of ancestor with PANTHER:PTN000212670" glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with SGD:S000000036 glycolytic process ; GO:0006096 | inferred from sequence or structural similarity with SGD:S000000036 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with SGD:S000000036 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000036 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000212670 CG2964 "IPR001697:Pyruvate kinase, IPR011037:Pyruvate kinase-like, insert domain, IPR015813:Pyruvate/Phosphoenolpyruvate kinase-like domain, IPR015793:Pyruvate kinase, barrel, IPR015795:Pyruvate kinase, C-terminal" CG2964 11-Aug-17 DroID_v2017_08 "Drer\pkmb, Drer\pkma" "Scer\PYK2, Scer\CDC19" "Cele\pyk-2, Cele\pyk-1" "Xtro\pklr, Xtro\pkm" "Mmus\Pkm, Mmus\Pklr" "Hsap\PKM, Hsap\PKLR" viable DRSC00554 IE 1.544119628 0.31574268 1.707965517 0.693171021 -0.097376394 0.096081655 FBgn0064115 GatC "Glutamyl-tRNA amidotransferase, subunit C" http://flybase.org/reports/FBgn0064115 protein_coding_gene - regulation of translational fidelity ; GO:0006450 | inferred from electronic annotation with InterPro:IPR003837 - "CG8969, CG33084-ORFA, CG33084, CG33649, GatC" IPR003837:Glu-tRNAGln amidotransferase C subunit CG33649 11-Aug-17 DroID_v2017_08 Drer\si:rp71-1c23.3 - Cele\Y66D12A.7 Xtro\gatc Mmus\Gatc Hsap\GATC DRSC03312 K 0.629697649 0.082733741 -0.021964253 0.19911291 -1.747062379 0.398493618 FBgn0003275 RpII18 RNA polymerase II 18kD subunit http://flybase.org/reports/FBgn0003275 "FBgn0014025, FBgn0064834" protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006110, InterPro:IPR006111, InterPro:IPR012293, InterPro:IPR020708 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000080812 RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000080812 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000080812" mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9193 inferred from sequence or structural similarity with SGD:S000006391 "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9193 inferred from sequence or structural similarity with SGD:S000006391 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN000080812 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000080812" "pol II, Pol II, RNAP, PolII, RNAP II, H5, polII, RNA Pol II, RNA pol II, CG1163, RNA polII, Dm6, RNApolII, RpABC14, BcDNA:RH21608, RpII18, Rpll18, RPB6_DROME, RPII18" "IPR006110:RNA polymerase, subunit omega/K/RPB6, IPR006111:Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit, IPR012293:RNA polymerase subunit, RPB6/omega, IPR020708:DNA-directed RNA polymerase, 14-18kDa subunit, conserved site, IPR028363:DNA-directed RNA polymerase, subunit RPB6" CG1163 11-Aug-17 DroID_v2017_08 Drer\polr2f Scer\RPO26 Cele\rpb-6 Xtro\polr2f Mmus\Polr2f Hsap\POLR2F DRSC12366 EK -1.366366063 0.659408359 1.642265617 -2.729166885 2.364746673 2.379237881 FBgn0025582 eIF3e eukaryotic translation initiation factor 3 subunit e http://flybase.org/reports/FBgn0025582 "FBgn0010945, FBgn0011424" protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC:3277 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000035120 translational initiation ; GO:0006413 | inferred from sequence or structural similarity neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay translational initiation ; GO:0006413 | inferred from sequence or structural similarity with HGNC:3277 phagocytosis ; GO:0006909 | inferred from mutant phenotype eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000035120 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with HGNC:3277 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000035120 intracellular membrane-bounded organelle ; GO:0043231 | inferred from direct assay "eIF3-p48/INT6, eIF3-S6, CG9677, l(3)10547, BcDNA.GM01233, Int6, eIF-3p48/INT-6, DINT6, l(3)j9E8, BcDNA:GM01233, eIF3e" "IPR000717:Proteasome component (PCI) domain, IPR016650:Eukaryotic translation initiation factor 3 subunit E, IPR019010:Eukaryotic translation initiation factor 3 subunit E, N-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain" CG9677 11-Aug-17 DroID_v2017_08 "Drer\eif3eb, Drer\eif3ea" - Cele\eif-3.E Xtro\eif3e Mmus\Eif3e Hsap\EIF3E embryonic stage -- adult stage embryonic stage -- adult stage "lethal,recessive,developmental rate defective,lethal - all die before end of first instar larval stage,some die during first instar larval stage,decreased cell number,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "female germline cell,germline clone,eye disc,somatic clone,wing disc,embryonic/larval brain" DRSC11199 EK -0.892382533 -1.268805357 -2.195370958 -3.944155929 -1.99799344 1.192092456 FBgn0264308 CG43778 - http://flybase.org/reports/FBgn0264308 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from sequence or structural similarity with rost "CG15639, CG43778, CG16970, FBgn 32504" IPR015943:WD40/YVTN repeat-like-containing domain CG43778 11-Aug-17 DroID_v2017_08 - - - - - - DRSC02549 E -0.759469167 0.045410406 0.854940605 -2.264219618 -0.583766922 0.492816467 FBgn0266722 Trs33 TRAPP subunit 33 http://flybase.org/reports/FBgn0266722 protein_coding_gene molecular_function ; GO:0003674 | no biological data available ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000005641 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000302156 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity cis-Golgi network ; GO:0005801 | inferred from biological aspect of ancestor with PANTHER:PTN000302156 trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000302156 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity TRAPP complex ; GO:0030008 | inferred from biological aspect of ancestor with PANTHER:PTN000302156 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000005641 "CG6196, Trs33p, Trs33, BcDNA:RH37427" "IPR024096:NO signalling/Golgi transport ligand-binding domain, IPR007194:Transport protein particle (TRAPP) component" CG6196 11-Aug-17 DroID_v2017_08 "Drer\trappc6b, Drer\trappc6bl" Scer\TRS33 Cele\trpp-6 "Xtro\trappc6a, Xtro\trappc6b" "Mmus\Trappc6a, Mmus\Trappc6b" "Hsap\TRAPPC6A, Hsap\TRAPPC6B" FBgn0053832 His2A:CG33832 His2A:CG33832 http://flybase.org/reports/FBgn0053832 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33832, His2A:CG33832" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33832 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113a14.26, Drer\LOC100334934, Drer\si:ch73-368j24.14, Drer\si:dkey-261m9.7, Drer\si:dkey-261m9.18, Drer\fbxl6, Drer\zgc:154164, Drer\si:dkey-23a13.7, Drer\mid1ip1l, Drer\LOC570115, Drer\zgc:173652, Drer\si:dkey-108k21.19, Drer\si:ch211-113a14.16, Drer\si:dkey-108k21.15, Drer\zgc:101846, Drer\zgc:195633, Drer\si:ch1073-159d7.10, Drer\si:dkey-261m9.15, Drer\h2afx, Drer\si:ch211-113a14.19, Drer\zgc:110434, Drer\si:dkey-23a13.20, Drer\si:ch211-113a14.7, Drer\si:ch1073-159d7.11, Drer\si:dkey-23a13.14, Drer\si:ch73-36p18.5, Drer\h2afy2, Drer\si:dkey-261m9.11, Drer\zgc:114037, Drer\LOC100332229, Drer\LOC100148591, Drer\si:dkey-108k21.26, Drer\si:ch211-113a14.11, Drer\si:ch73-368j24.13" "Scer\HTA1, Scer\HTA2" "Cele\htas-1, Cele\his-19, Cele\his-65, Cele\his-3, Cele\his-57, Cele\his-35, Cele\his-12, Cele\his-43, Cele\his-61, Cele\his-21, Cele\his-51, Cele\his-68, Cele\his-47, Cele\his-33, Cele\his-7, Cele\his-16, Cele\his-53, Cele\his-30" "Xtro\LOC100485081, Xtro\h2afy2, Xtro\LOC100492975, Xtro\LOC100485854, Xtro\LOC100487455, Xtro\LOC100487632, Xtro\LOC100497614, Xtro\LOC101731006, Xtro\h2afj, Xtro\LOC100486672, Xtro\hist1h2ah, Xtro\h2afy, Xtro\hist1h2am, Xtro\LOC101734900, Xtro\hist1h2aa, Xtro\hist1h2ad, Xtro\hist1h2aj, Xtro\LOC100496244, Xtro\LOC100487067, Xtro\h2afx" "Mmus\Hist1h2ao, Mmus\Hist1h2ab, Mmus\Hist1h2af, Mmus\H2al1j, Mmus\Hist3h2a, Mmus\H2afy, Mmus\H2afj, Mmus\Hist1h2ag, Mmus\Hist2h2ab, Mmus\Gm14920, Mmus\H2afb3, Mmus\H2afy2, Mmus\Hist2h2ac, Mmus\Hist1h2ae, Mmus\Hist2h2aa1, Mmus\H2al2b, Mmus\Hist1h2ai, Mmus\Hist1h2ad, Mmus\Hist1h2ak, Mmus\H2afb2, Mmus\Hist2h2aa2, Mmus\H2al1n, Mmus\Hist1h2an, Mmus\H2afx, Mmus\H2afb1, Mmus\Hist2h3c1, Mmus\Hist1h2aa, Mmus\Hist1h2ah, Mmus\Hist1h2ac, Mmus\H2al2c, Mmus\Hist1h2ap" "Hsap\HIST1H2AL, Hsap\H2AFB1, Hsap\H2AFY2, Hsap\HIST1H2AB, Hsap\HIST3H2A, Hsap\HIST1H2AA, Hsap\HIST1H2AM, Hsap\HIST1H2AH, Hsap\HIST1H2AG, Hsap\H2AFJ, Hsap\HIST1H2AD, Hsap\HIST1H2AC, Hsap\H2AFX, Hsap\HIST2H2AB, Hsap\HIST1H2AI, Hsap\H2AFB3, Hsap\HIST1H2AE, Hsap\HIST2H2AC, Hsap\HIST2H2AA3, Hsap\HIST2H2AA4, Hsap\H2AFY, Hsap\HIST1H2AK, Hsap\H2AFB2, Hsap\HIST1H2AJ" FBgn0053868 His2B:CG33868 His2B:CG33868 http://flybase.org/reports/FBgn0053868 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33868, His2B:CG33868" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33868 11-Aug-17 DroID_v2017_08 "Drer\LOC100334869, Drer\hist1h2ba, Drer\si:dkey-261m9.6, Drer\si:dkey-108k21.11, Drer\si:dkey-23a13.16, Drer\LOC100329290, Drer\si:ch73-368j24.10, Drer\zgc:114046, Drer\si:ch1073-159d7.13, Drer\LOC100329560, Drer\si:ch1073-153i20.3, Drer\hist2h2l, Drer\zgc:173585, Drer\si:ch211-113a14.15, Drer\si:ch1073-159d7.5, Drer\si:dkey-23a13.5, Drer\zgc:92591, Drer\si:ch73-36p18.3, Drer\ano9a, Drer\zgc:173587, Drer\zgc:194989, Drer\si:ch211-113a14.29, Drer\si:ch211-113a14.28, Drer\si:ch73-368j24.8, Drer\si:dkey-23a13.1, Drer\si:dkey-261m9.19, Drer\si:ch211-113a14.11, Drer\zgc:112234, Drer\LOC100334559, Drer\si:dkey-23a13.8, Drer\si:dkey-108k21.27" "Scer\HTB2, Scer\HTB1" "Cele\his-54, Cele\his-4, Cele\his-11, Cele\his-58, Cele\his-8, Cele\his-22, Cele\his-62, Cele\his-66, Cele\his-41, Cele\his-44, Cele\his-15, Cele\his-39, Cele\his-20, Cele\his-34, Cele\his-29, Cele\his-52, Cele\his-48" "Xtro\LOC100496181, Xtro\LOC100492632, Xtro\LOC100496436, Xtro\LOC100495415, Xtro\LOC100497915, Xtro\LOC101733489, Xtro\LOC101731959, Xtro\LOC100495041, Xtro\LOC101734862, Xtro\LOC100495396, Xtro\LOC101735164, Xtro\LOC100486870, Xtro\LOC100485134, Xtro\LOC101733171, Xtro\LOC100485294, Xtro\LOC101730940, Xtro\LOC100487485, Xtro\LOC101734494, Xtro\hist1h2bj, Xtro\LOC100498647, Xtro\LOC100498329, Xtro\hist1h2bk, Xtro\LOC101731067, Xtro\LOC100498072, Xtro\LOC101733828, Xtro\LOC100497082, Xtro\LOC100496445, Xtro\LOC100498553, Xtro\LOC100495578, Xtro\LOC100486150, Xtro\hist2h2be, Xtro\hist1h2bm, Xtro\LOC101731852, Xtro\LOC101735218" "Mmus\H2bfm, Mmus\Hist1h2bk, Mmus\Hist2h2bb, Mmus\1700024P04Rik, Mmus\Hist1h2br, Mmus\Hist2h2be, Mmus\Hist1h2bq, Mmus\Hist1h2bc, Mmus\Hist1h2ba, Mmus\Hist1h2bh, Mmus\Hist1h2bm, Mmus\Hist1h2bg, Mmus\Hist1h2bl, Mmus\Hist1h2be, Mmus\Hist3h2ba, Mmus\Hist1h2bj, Mmus\Hist1h2bp, Mmus\Hist1h2bn, Mmus\Hist1h2bb, Mmus\Hist1h2bf" "Hsap\HIST1H2BL, Hsap\HIST1H2BM, Hsap\HIST1H2BO, Hsap\HIST1H2BK, Hsap\HIST1H2BG, Hsap\HIST1H2BI, Hsap\HIST2H2BE, Hsap\HIST1H2BF, Hsap\H2BFWT, Hsap\HIST1H2BA, Hsap\HIST1H2BJ, Hsap\HIST1H2BE, Hsap\HIST3H2BB, Hsap\HIST1H2BD, Hsap\HIST1H2BB, Hsap\H2BFM, Hsap\HIST1H2BH, Hsap\HIST1H2BN, Hsap\HIST2H2BF, Hsap\HIST1H2BC" FBgn0037612 CG8112 - http://flybase.org/reports/FBgn0037612 protein_coding_gene cholesterol O-acyltransferase activity ; GO:0034736 | inferred from electronic annotation with InterPro:IPR030687 O-acyltransferase activity ; GO:0008374 | inferred from biological aspect of ancestor with PANTHER:PTN000045225 cholesterol esterification ; GO:0034435 | inferred from electronic annotation with InterPro:IPR030687 cholesterol homeostasis ; GO:0042632 | inferred from electronic annotation with InterPro:IPR030687 cholesterol metabolic process ; GO:0008203 | inferred from biological aspect of ancestor with PANTHER:PTN000823452 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000045225 CG8112 "IPR004299:Membrane bound O-acyl transferase, MBOAT, IPR030687:Sterol O-acyltransferase, metazoa, IPR014371:Sterol O-acyltransferase, ACAT/DAG/ARE types" CG8112 11-Aug-17 DroID_v2017_08 "Drer\dgat1b, Drer\soat2, Drer\soat1, Drer\dgat1a" "Scer\ARE1, Scer\ARE2" "Cele\mboa-2, Cele\mboa-1" "Xtro\soat2, Xtro\soat1" "Mmus\Dgat1, Mmus\Soat2, Mmus\Soat1" "Hsap\SOAT1, Hsap\SOAT2, Hsap\DGAT1" viable FBgn0022981 rpk ripped pocket http://flybase.org/reports/FBgn0022981 - protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 detection of mechanical stimulus involved in sensory perception of pain ; GO:0050966 | inferred from expression pattern sensory perception of touch ; GO:0050975 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 axon ; GO:0030424 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "dGNaC1, RPK, GNaC1, CG1058, rpk, ppk2" "IPR001873:Epithelial sodium channel, IPR020903:Epithelial sodium channel, conserved site" CG1058 11-Aug-17 DroID_v2017_08 "Drer\asic4a, Drer\asic4b, Drer\asic2, Drer\asic1b, Drer\asic1a, Drer\asic1c" - "Cele\del-7, Cele\acd-2, Cele\acd-1, Cele\asic-2, Cele\delm-2, Cele\del-4, Cele\acd-3, Cele\del-6, Cele\flr-1, Cele\acd-5, Cele\del-8, Cele\delm-1, Cele\del-9, Cele\mec-4, Cele\mec-10, Cele\acd-4, Cele\deg-1" "Xtro\scnn1b, Xtro\scnn1g, Xtro\scnn1a, Xtro\scnn1d, Xtro\asic1, Xtro\asic4, Xtro\asic5" "Mmus\Asic3, Mmus\Asic4, Mmus\Asic2, Mmus\Scnn1a, Mmus\Asic1, Mmus\Asic5, Mmus\Scnn1b, Mmus\Scnn1g" "Hsap\SCNN1D, Hsap\ASIC4, Hsap\ASIC5, Hsap\SCNN1A, Hsap\ASIC3, Hsap\SCNN1G, Hsap\ASIC1, Hsap\SCNN1B, Hsap\ASIC2" " embryonic stage&&adult stage , adult stage , oogenesis stage | stage S10 , oogenesis stage | stage >=S5 , adult stage | male , spermatogenesis && adult stage , embryonic stage | 0-3 hr , embryonic stage | 0-4 hr , embryonic stage | stage <=8 " " ovary

, nurse cell

, seminal vesicle

, gonad

, oocyte

, follicle cell

, primary spermatocyte cyst

" "touch sensitivity defective,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,viable" "dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0030747 CG4301 - http://flybase.org/reports/FBgn0030747 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006539 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR006539 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from sequence or structural similarity with SGD:S000000024 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 phospholipid translocation ; GO:0045332 | inferred from sequence or structural similarity with SGD:S000000024 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR006539 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000642368" "CG4301, DmCG4301" "IPR001757:P-type ATPase, IPR006539:P-type ATPase, subfamily IV, IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N, IPR032630:P-type ATPase, C-terminal, IPR032631:P-type ATPase, N-terminal" CG4301 11-Aug-17 DroID_v2017_08 "Drer\atp10a, Drer\atp11c, Drer\si:dkey-211e20.10, Drer\atp11a, Drer\atp10d, Drer\atp10b" "Scer\DRS2, Scer\DNF3" "Cele\tat-4, Cele\tat-3" "Xtro\atp11c, Xtro\atp11a, Xtro\atp11b" "Mmus\Atp10b, Mmus\Atp11b, Mmus\Atp11c, Mmus\Atp11a, Mmus\Atp10a" "Hsap\ATP10A, Hsap\ATP11B, Hsap\ATP10B, Hsap\ATP11C, Hsap\ATP11A, Hsap\ATP10D" "viable,body color defective" mesothoracic tergum FBgn0053850 His2A:CG33850 His2A:CG33850 http://flybase.org/reports/FBgn0053850 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33850, His2A:CG33850" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33850 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-108k21.19, Drer\zgc:195633, Drer\si:ch211-113a14.26, Drer\si:dkey-261m9.7, Drer\zgc:114037, Drer\h2afx, Drer\si:dkey-261m9.11, Drer\si:dkey-261m9.18, Drer\si:dkey-23a13.14, Drer\LOC100334934, Drer\si:ch73-368j24.13, Drer\si:ch211-113a14.11, Drer\si:dkey-261m9.15, Drer\LOC570115, Drer\si:ch73-36p18.5, Drer\si:dkey-23a13.7, Drer\zgc:101846, Drer\si:ch1073-159d7.10, Drer\si:ch211-113a14.19, Drer\zgc:173652, Drer\zgc:154164, Drer\LOC100148591, Drer\si:ch1073-159d7.11, Drer\si:dkey-108k21.26, Drer\si:dkey-108k21.15, Drer\LOC100332229, Drer\si:dkey-23a13.20, Drer\h2afy2, Drer\zgc:110434, Drer\si:ch73-368j24.14, Drer\si:ch211-113a14.16, Drer\si:ch211-113a14.7, Drer\fbxl6" "Scer\HTA1, Scer\HTA2" "Cele\his-51, Cele\his-35, Cele\his-12, Cele\his-33, Cele\his-3, Cele\his-43, Cele\his-53, Cele\his-7, Cele\his-65, Cele\his-68, Cele\his-21, Cele\his-30, Cele\his-19, Cele\his-61, Cele\his-47, Cele\his-57, Cele\htas-1, Cele\his-16" "Xtro\h2afy, Xtro\hist1h2am, Xtro\h2afj, Xtro\hist1h2ad, Xtro\hist1h2aa, Xtro\h2afx, Xtro\hist1h2aj, Xtro\h2afy2, Xtro\hist1h2ah" "Mmus\Hist1h2ak, Mmus\Hist1h2ae, Mmus\H2afx, Mmus\Hist1h2aa, Mmus\Hist1h2ag, Mmus\Hist3h2a, Mmus\H2al1j, Mmus\H2afy2, Mmus\Hist1h2ac, Mmus\Hist1h2ai, Mmus\Hist2h2aa1, Mmus\H2al2c, Mmus\Hist1h2ah, Mmus\H2al1n, Mmus\Hist1h2ad, Mmus\H2afj, Mmus\H2afb1, Mmus\Hist1h2ab, Mmus\Hist2h2ab, Mmus\H2afb2, Mmus\H2afb3, Mmus\Hist1h2an, Mmus\Gm14920, Mmus\Hist2h2aa2, Mmus\Hist1h2af, Mmus\Hist2h3c1, Mmus\Hist2h2ac, Mmus\H2al2b, Mmus\H2afy, Mmus\Hist1h2ap, Mmus\Hist1h2ao" "Hsap\HIST1H2AH, Hsap\HIST3H2A, Hsap\HIST1H2AD, Hsap\HIST2H2AC, Hsap\HIST2H2AA4, Hsap\HIST2H2AA3, Hsap\HIST1H2AB, Hsap\HIST1H2AI, Hsap\HIST1H2AG, Hsap\HIST1H2AC, Hsap\HIST1H2AJ, Hsap\HIST1H2AM, Hsap\HIST1H2AE, Hsap\H2AFJ, Hsap\H2AFB3, Hsap\H2AFY, Hsap\HIST1H2AA, Hsap\HIST2H2AB, Hsap\H2AFX, Hsap\HIST1H2AL, Hsap\H2AFY2, Hsap\H2AFB2, Hsap\HIST1H2AK, Hsap\H2AFB1" FBgn0035271 CG2021 - http://flybase.org/reports/FBgn0035271 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000400405 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:20471 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000003783 inferred from sequence or structural similarity with protein_id:AAD56232 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000400465" U6 snRNP ; GO:0005688 | inferred from electronic annotation with InterPro:IPR034103 U6 snRNP ; GO:0005688 | non-traceable author statement U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000400465 precatalytic spliceosome ; GO:0071011 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with protein_id:AAD56232 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000003783 inferred from sequence or structural similarity with protein_id:AAD56232 "CG2021, l(3)neo7, l(3)62Be, neo7" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR034103:Sm-like protein Lsm8" CG2021 11-Aug-17 DroID_v2017_08 Drer\lsm8 "Scer\LSM8, Scer\MAK31, Scer\SMB1" Cele\lsm-8 Xtro\lsm8 Mmus\Lsm8 Hsap\LSM8 FBgn0261710 nocte no circadian temperature entrainment http://flybase.org/reports/FBgn0261710 protein_coding_gene molecular_function ; GO:0003674 | no biological data available temperature compensation of the circadian clock ; GO:0010378 | inferred from mutant phenotype entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "nocte, CG17255" "IPR019400:Peptidase C65, otubain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR009738:BAT2, N-terminal" CG17255 11-Aug-17 DroID_v2017_08 "Drer\prrc2a, Drer\prrc2b, Drer\prrc2c" - Cele\F52G3.1 "Xtro\prrc2a, Xtro\prrc2c" "Mmus\Prrc2b, Mmus\Prrc2a, Mmus\Prrc2c" "Hsap\PRRC2B, Hsap\PRRC2C, Hsap\PRRC2A" DRSC18123 K -0.44634418 -0.530876368 0.170300358 -1.48619864 1.70769046 1.436671064 FBgn0053895 His4:CG33895 His4:CG33895 http://flybase.org/reports/FBgn0053895 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33895, His4:CG33895" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33895 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113a14.6, Drer\LOC570405, Drer\zgc:194989, Drer\LOC794549, Drer\LOC100331412, Drer\LOC562770, Drer\hist1h4l, Drer\si:ch73-368j24.1, Drer\si:dkey-23a13.7, Drer\si:ch73-36p18.3, Drer\si:dkey-261m9.18, Drer\si:dkey-108k21.28, Drer\si:ch73-368j24.14, Drer\zgc:154164, Drer\si:dkey-108k21.12, Drer\si:dkey-261m9.17, Drer\si:ch73-36p18.4, Drer\LOC100329358, Drer\zgc:153409, Drer\si:ch211-113a14.26, Drer\zgc:163040, Drer\si:ch211-113a14.17, Drer\si:dkey-108k21.19, Drer\LOC100150038" "Scer\HHF1, Scer\HHF2" "Cele\his-56, Cele\his-14, Cele\his-46, Cele\his-60, Cele\his-5, Cele\his-28, Cele\his-37, Cele\his-1, Cele\his-38, Cele\his-67, Cele\his-18, Cele\his-10, Cele\his-31, Cele\his-26, Cele\his-50, Cele\his-64" "Xtro\hist1h4k, Xtro\hist1h4c, Xtro\LOC100493041" "Mmus\Hist1h4a, Mmus\Hist1h4k, Mmus\Hist1h4n, Mmus\Hist1h4h, Mmus\Hist1h4m, Mmus\Hist1h4f, Mmus\Hist1h4c, Mmus\Hist2h4, Mmus\Hist1h4i, Mmus\Hist1h4j, Mmus\Hist4h4, Mmus\Hist1h4b, Mmus\Hist1h4d" "Hsap\HIST2H4B, Hsap\HIST4H4, Hsap\HIST1H4C, Hsap\HIST1H4I, Hsap\HIST1H4H, Hsap\HIST1H4D, Hsap\HIST1H4J, Hsap\HIST1H4K, Hsap\HIST1H4A, Hsap\HIST1H4F, Hsap\HIST1H4L, Hsap\HIST1H4B, Hsap\HIST1H4G, Hsap\HIST2H4A, Hsap\HIST1H4E" FBgn0004057 Zw Zwischenferment http://flybase.org/reports/FBgn0004057 - protein_coding_gene "NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR022674, InterPro:IPR022675 glucose-6-phosphate dehydrogenase activity ; GO:0004345 | inferred from mutant phenotype" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001282, InterPro:IPR019796, InterPro:IPR022674, InterPro:IPR022675 glucose metabolic process ; GO:0006006 | inferred from electronic annotation with InterPro:IPR001282, InterPro:IPR019796, InterPro:IPR022674, InterPro:IPR022675 glucose 6-phosphate metabolic process ; GO:0051156 | inferred from sequence or structural similarity with UniProtKB:P11413 NADP metabolic process ; GO:0006739 | inferred from sequence or structural similarity with UniProtKB:P11413" - "G6-PD, G6PD, G6pdh, G-6-PD, G6pd, G-6pd, G6PDH, g6pd, G-6-pdh, G6-pd, G-6PD, CG12529, Zw, zw" "IPR001282:Glucose-6-phosphate dehydrogenase, IPR016040:NAD(P)-binding domain, IPR019796:Glucose-6-phosphate dehydrogenase, active site, IPR022674:Glucose-6-phosphate dehydrogenase, NAD-binding, IPR022675:Glucose-6-phosphate dehydrogenase, C-terminal" CG12529 11-Aug-17 DroID_v2017_08 "Drer\g6pd, Drer\h6pd" Scer\ZWF1 Cele\gspd-1 "Xtro\h6pd, Xtro\g6pd" "Mmus\G6pd2, Mmus\G6pdx, Mmus\H6pd" "Hsap\H6PD, Hsap\G6PD" adult stage "long lived,oxidative stress response defective,female fertile,lethal,electrophoretic variant,viable,body color defective" mesothoracic tergum DRSC20303 K -0.424696214 -0.02958462 -0.679454002 -0.353407642 0.317753808 1.661294432 FBgn0026372 RpL23A Ribosomal protein L23A http://flybase.org/reports/FBgn0026372 "FBgn0014878, FBgn0025226, FBgn0025992" protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR012678, InterPro:IPR013025 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000178698 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "RpL23a, 153215_at, CG7977, L23a, rpl23a, PBP-3, rpL25, clone 1.4, anon-EST:Liang-1.4, anon-EST:fe2D1, RpL25, RpL23A, L23A, RPL23a, Rp L23A" "IPR001014:Ribosomal protein L23/L25, conserved site, IPR005633:Ribosomal protein L23/L25, N-terminal, IPR012678:Ribosomal protein L23/L15e core domain, IPR013025:Ribosomal protein L25/L23" CG7977 11-Aug-17 DroID_v2017_08 Drer\rpl23a Scer\RPL25 "Cele\rpl-25.1, Cele\rpl-25.2" Xtro\rpl23a Mmus\Rpl23a Hsap\RPL23A "viable,fertile" DRSC08694 IEK -2.589151873 -1.441711742 -0.404329904 -4.032673527 1.797411205 4.89635514 FBgn0262699 fzr fizzy-related http://flybase.org/reports/FBgn0262699 protein_coding_gene anaphase-promoting complex binding ; GO:0010997 | inferred from electronic annotation with InterPro:IPR033010 ubiquitin-protein transferase activator activity ; GO:0097027 | inferred from electronic annotation with InterPro:IPR033010 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay positive regulation of ubiquitin protein ligase activity ; GO:1904668 | inferred from electronic annotation with InterPro:IPR033010 glial cell migration ; GO:0008347 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype protein catabolic process ; GO:0030163 | inferred from mutant phenotype positive regulation of exit from mitosis ; GO:0031536 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype exit from mitosis ; GO:0010458 | NOT inferred from mutant phenotype glial cell differentiation ; GO:0010001 | inferred from direct assay anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from direct assay regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay anaphase-promoting complex ; GO:0005680 | inferred from direct assay "fzr, Fzr, cdh1, redax, CG3000, Cdh1, Cdh1/Fzr, rap/fizzy-related, Hec/Cdh[Fzr], Cdh[Fzr], Cdh1[Fzr], rap/Fzr, l(1)G0418, l(1)G0326, CDH1, dFZR, wex, anon-WO03040301.193, Rap/Fzr, rap/fzr, APC/C[Fzr/Cdh1], Fxr, Fzr/rap, rap, fzr/Cdh1" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR033010:The WD repeat Cdc20/Fizzy family, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG3000 11-Aug-17 DroID_v2017_08 "Drer\cdc20, Drer\fzr1a, Drer\fzr1b" "Scer\AMA1, Scer\CDH1, Scer\CDC20" "Cele\fzr-1, Cele\fzy-1" "Xtro\fzr1, Xtro\cdc20" "Mmus\Cdc20, Mmus\Fzr1, Mmus\Cdc20b" "Hsap\FZR1, Hsap\CDC20B, Hsap\CDC20" " adult stage , embryonic stage | stage 11 , embryonic stage | syncytial blastoderm " " spermatocyte

, posterior midgut proper primordium

, anterior midgut proper primordium

, salivary gland body primordium

" embryonic stage salivary gland body primordium

DRSC28236 K 0.660458959 0.63595635 0.512118996 0.771260473 -1.776595119 -1.40118134 FBgn0039218 Rpb10 Rpb10 http://flybase.org/reports/FBgn0039218 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000268, InterPro:IPR009057, InterPro:IPR020789 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000602008 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000602007 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000005736 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000602008 RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000602008" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000005736 "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from biological aspect of ancestor with PANTHER:PTN000602008 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000602008 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN000602008 DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000005736" "CG13628, RPB10, BcDNA:SD08670, Rpb10" "IPR000268:DNA-directed RNA polymerase, subunit N/Rpb10, IPR023580:RNA polymerase subunit RPB10, IPR020789:RNA polymerases, subunit N, zinc binding site" CG13628 11-Aug-17 DroID_v2017_08 Drer\polr2l Scer\RPB10 Cele\rpb-10 "Xtro\polr2l.1, Xtro\polr2l.2" Mmus\Polr2l Hsap\POLR2L "lethal - all die before end of pupal stage,some die during pupal stage" DRSC14630 IK -2.341387531 3.983453064 0.168190416 -0.626602177 2.628506925 1.551170702 FBgn0034181 CG8963 - http://flybase.org/reports/FBgn0034181 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR003890 locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype - CG8963 "IPR003890:MIF4G-like, type 3, IPR016024:Armadillo-type fold" CG8963 11-Aug-17 DroID_v2017_08 "Drer\mif4gdb, Drer\ctif, Drer\mif4gda, Drer\paip1" Scer\TIF4631 Cele\ifg-1 "Xtro\paip1, Xtro\ctif, Xtro\mif4gd" "Mmus\Mif4gd, Mmus\Ctif, Mmus\Paip1" "Hsap\PAIP1, Hsap\MIF4GD" "smell perception defective,viable,behavior defective,recessive,visible,body color defective,partially lethal - majority die,some die during pupal stage" "wing,mesothoracic tergum" DRSC07302 IEK -0.181245039 -3.014895155 -0.670909515 -3.515190922 0.023378029 1.613646248 FBgn0265595 CG44422 - http://flybase.org/reports/FBgn0265595 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" - - "CG44422, CG34144, CG11105, CG12625, CG42683, Dm_X:57642" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG44422 11-Aug-17 DroID_v2017_08 "Drer\guca1g, Drer\rcvrna, Drer\guca1e, Drer\si:ch211-245j22.3, Drer\kcnip1b, Drer\si:ch211-103a14.5, Drer\hpcal1, Drer\efcab1, Drer\vsnl1a, Drer\ncs1a, Drer\vsnl1b, Drer\hpcal4, Drer\rcvrn3, Drer\guca1c, Drer\kcnip3b, Drer\hpca, Drer\usp32, Drer\guca1a, Drer\rcvrnb, Drer\kcnip1a, Drer\ncalda, Drer\ncs1b, Drer\ncaldb, Drer\guca1b, Drer\si:ch211-145b13.5, Drer\rcvrn2, Drer\kcnip3a, Drer\kcnip4, Drer\kcnip2, Drer\guca1d" Scer\FRQ1 "Cele\ncs-3, Cele\ncs-2, Cele\ncs-5, Cele\ncs-6, Cele\ncs-1, Cele\ncs-7, Cele\ncs-4" "Xtro\hpca, Xtro\guca1b, Xtro\kcnip3, Xtro\ncs1, Xtro\kcnip4, Xtro\hpcal1, Xtro\vsnl1, Xtro\guca1a, Xtro\efcab1, Xtro\rcvrn.2, Xtro\kcnip2, Xtro\kcnip1, Xtro\ncald, Xtro\guca1c" "Mmus\Nucb2, Mmus\Kcnip1, Mmus\Kcnip3, Mmus\Usp32, Mmus\Rcvrn, Mmus\Vsnl1, Mmus\1700109H08Rik, Mmus\Guca1a, Mmus\Guca1b, Mmus\Ncs1, Mmus\Hpcal1, Mmus\Hpca, Mmus\Kcnip2, Mmus\Hpcal4, Mmus\Efcab1, Mmus\Kcnip4, Mmus\Ncald" "Hsap\RCVRN, Hsap\KCNIP1, Hsap\USP32, Hsap\KCNIP3, Hsap\KCNIP2, Hsap\NCALD, Hsap\NUCB2, Hsap\HPCAL4, Hsap\HPCA, Hsap\GUCA1C, Hsap\KCNIP4, Hsap\GUCA1A, Hsap\VSNL1, Hsap\NCS1, Hsap\GUCA1B, Hsap\HPCAL1, Hsap\EFCAB1" DRSC19380 K 0.547914771 0.809477691 -1.038484854 -0.04790036 -0.101613097 1.563859101 FBgn0035859 CG13678 - http://flybase.org/reports/FBgn0035859 protein_coding_gene - - - "BcDNA:RE24439, CG13678" - CG13678 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC10036 K -1.477587327 1.159264653 0.04160639 0.045127567 -1.640368878 -1.130504683 FBgn0086710 RpL30 Ribosomal protein L30 http://flybase.org/reports/FBgn0086710 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000154874 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000231 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 peripheral nervous system development ; GO:0007422 | non-traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype growth ; GO:0040007 | inferred from mutant phenotype cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "l(2)01265, plume, l(2)k09918, anon-EST:fe1D4, L30, CG10652, BcDNA:RE25263, BcDNA:RH09938, l(2)SH0229, RpL30, l(2)SH2 0229, Rpl30, RPL30, Rp L30" "IPR004038:Ribosomal protein L7Ae/L30e/S12e/Gadd45, IPR000231:Ribosomal protein L30e, IPR029064:50S ribosomal protein L30e-like, IPR022991:Ribosomal protein L30e, conserved site" CG10652 11-Aug-17 DroID_v2017_08 Drer\rpl30 Scer\RPL30 Cele\rpl-30 Xtro\rpl30 "Mmus\Rpl30, Mmus\Gm5481" Hsap\RPL30 DRSC02087 EK -0.516873067 -1.346290054 0.465298829 -4.113185249 0.552455928 2.649441227 FBgn0039065 Rad60 Rad60 http://flybase.org/reports/FBgn0039065 protein_coding_gene protein tag ; GO:0031386 | inferred from biological aspect of ancestor with PANTHER:PTN001316528 double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype protein sumoylation ; GO:0016925 | inferred from biological aspect of ancestor with PANTHER:PTN001316528 nuclear periphery ; GO:0034399 | inferred from direct assay "CG4449, Rad60, drad60, RENi, dRad60" "IPR029071:Ubiquitin-related domain, IPR022617:Rad60/SUMO-like domain" CG4449 11-Aug-17 DroID_v2017_08 - Scer\ESC2 Cele\T04A8.8 - - Hsap\NFATC2IP viable FBgn0005429 l(1)EN14 lethal (1) from Eugene Nonautonomous 14 http://flybase.org/reports/FBgn0005429 - gene - - - l(1)EN14 - - 11-Aug-17 DroID_v2017_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" embryonic/larval cuticle FBgn0002248 l(3)68Db lethal (3) 68Db http://flybase.org/reports/FBgn0002248 - gene - - - "rsg9, l(3)rsg9, l(3)68Db" - - 11-Aug-17 DroID_v2017_08 - - - - - - lethal FBgn0031835 CG11319 - http://flybase.org/reports/FBgn0031835 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR001375 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001375, InterPro:IPR002469" - CG11319 "IPR002469:Dipeptidylpeptidase IV, N-terminal domain, IPR029058:Alpha/Beta hydrolase fold, IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain" CG11319 11-Aug-17 DroID_v2017_08 "Drer\dpp6a, Drer\dpp4, Drer\fap, Drer\apeh, Drer\zgc:136971, Drer\LOC101883320, Drer\dpp6b, Drer\LOC101886435" "Scer\DAP2, Scer\STE13" "Cele\dpf-1, Cele\dpf-2" "Xtro\apeh, Xtro\dpp6, Xtro\dpp10, Xtro\dpp4" "Mmus\Fap, Mmus\Dpp10, Mmus\Dpp6, Mmus\Dpp4, Mmus\Apeh" "Hsap\FAP, Hsap\DPP4, Hsap\DPP10, Hsap\DPP6, Hsap\APEH" "viable,fertile" DRSC00942 K 0.472057899 -1.086596801 -0.357186086 -0.7162365 0.747019304 2.031985905 FBgn0053889 His4:CG33889 His4:CG33889 http://flybase.org/reports/FBgn0053889 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33889, His4:CG33889" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33889 11-Aug-17 DroID_v2017_08 "Drer\hist1h4l, Drer\zgc:194989, Drer\si:dkey-108k21.19, Drer\si:dkey-261m9.17, Drer\zgc:163040, Drer\si:ch73-36p18.4, Drer\LOC100331412, Drer\si:ch211-113a14.6, Drer\LOC794549, Drer\LOC100329358, Drer\zgc:154164, Drer\LOC100150038, Drer\LOC562770, Drer\si:dkey-108k21.12, Drer\si:ch73-368j24.14, Drer\si:dkey-23a13.7, Drer\si:dkey-261m9.18, Drer\si:ch211-113a14.26, Drer\si:dkey-108k21.28, Drer\LOC570405, Drer\si:ch211-113a14.17, Drer\si:ch73-368j24.1, Drer\zgc:153409, Drer\si:ch73-36p18.3" "Scer\HHF2, Scer\HTA2, Scer\HTA1, Scer\HHF1" "Cele\his-67, Cele\his-50, Cele\his-60, Cele\his-10, Cele\his-1, Cele\his-38, Cele\his-37, Cele\his-18, Cele\his-46, Cele\his-56, Cele\his-28, Cele\his-31, Cele\his-14, Cele\his-5, Cele\his-64, Cele\his-26" "Xtro\hist1h4c, Xtro\hist1h4k, Xtro\LOC100493041" "Mmus\Hist1h4k, Mmus\Hist1h4n, Mmus\Hist1h4c, Mmus\Hist1h4b, Mmus\Hist1h4d, Mmus\Hist1h4a, Mmus\Hist1h4f, Mmus\Hist1h2ap, Mmus\Hist2h4, Mmus\Hist1h4h, Mmus\Hist1h4j, Mmus\Hist1h4i, Mmus\Hist4h4, Mmus\Hist1h4m" "Hsap\HIST2H4A, Hsap\HIST1H4A, Hsap\HIST1H4L, Hsap\HIST1H4D, Hsap\HIST4H4, Hsap\HIST1H4K, Hsap\HIST1H4J, Hsap\HIST1H4G, Hsap\HIST1H4E, Hsap\HIST2H4B, Hsap\HIST1H4F, Hsap\HIST1H4B, Hsap\HIST1H4I, Hsap\HIST1H4H, Hsap\HIST1H4C" FBgn0036978 Toll-9 Toll-9 http://flybase.org/reports/FBgn0036978 protein_coding_gene - signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000157 - "Dm Toll-9, dToll9, Toll 9, toll, dTLR9, Tl-9, Tl-5, Tak/Toll-like, CT17508, CG5528, Toll-9, TOLL 9" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG5528 11-Aug-17 DroID_v2017_08 "Drer\tlr8b, Drer\tlr18, Drer\tlr4bb, Drer\tlr9, Drer\LOC572462, Drer\cd180, Drer\tlr7, Drer\tlr5b, Drer\LOC100005571, Drer\zgc:101569, Drer\tlr1, Drer\tlr4ba, Drer\tlr21, Drer\LOC100332783, Drer\tlr2, Drer\tlr5a, Drer\tlr3, Drer\LOC100332583, Drer\tlr20.2" - - "Xtro\LOC100485706, Xtro\LOC100485201, Xtro\tlr7, Xtro\LOC100485164, Xtro\LOC100485512, Xtro\tlr6, Xtro\LOC100495326, Xtro\tlr3, Xtro\tlr2, Xtro\tlr5, Xtro\tlr9" "Mmus\Tlr5, Mmus\Tlr3, Mmus\Tlr6, Mmus\Tlr1, Mmus\Tlr4, Mmus\Tlr8, Mmus\Tlr13, Mmus\Tlr12, Mmus\Tlr7, Mmus\Tlr9, Mmus\Tlr11, Mmus\Cd180, Mmus\Tlr2" "Hsap\TLR8, Hsap\TLR2, Hsap\TLR9, Hsap\TLR6, Hsap\TLR10, Hsap\CD180, Hsap\TLR7, Hsap\TLR1, Hsap\TLR3, Hsap\TLR4, Hsap\TLR5, Hsap\GP1BA" "lethal,short lived,developmental rate defective,partially lethal - majority die,some die during embryonic stage,viable,fertile" "leg,eye,embryonic/larval hemocyte" FBgn0036257 RhoGAP68F Rho GTPase activating protein at 68F http://flybase.org/reports/FBgn0036257 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from direct assay Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab4 Rho protein signal transduction ; GO:0007266 | inferred from direct assay negative regulation of stress fiber assembly ; GO:0051497 | inferred from direct assay negative regulation of endocytic recycling ; GO:2001136 | inferred from direct assay imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype ventral furrow formation ; GO:0007370 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay "CG6811, CG 6811, RhoGAP68F, RhoGAP" "IPR000198:Rho GTPase-activating protein domain, IPR001251:CRAL-TRIO lipid binding domain, IPR008936:Rho GTPase activation protein" CG6811 11-Aug-17 DroID_v2017_08 Drer\arhgap1 "Scer\ECM25, Scer\BEM2, Scer\BAG7" Cele\rga-1 "Xtro\arhgap1, Xtro\fam13b" "Mmus\Arhgap1, Mmus\Arhgap8, Mmus\Prr5" "Hsap\ARHGAP1, Hsap\ARHGAP8, Hsap\PRR5, Hsap\PRR5-ARHGAP8" "partially lethal - majority die,lethal,maternal effect,neuroanatomy defective,viable" "embryonic/first instar larval cuticle,maternal effect,ventral furrow,intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0031047 Rcd-1 Required for cell differentiation 1 http://flybase.org/reports/FBgn0031047 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of translation ; GO:0017148 | inferred from direct assay mRNA catabolic process ; GO:0006402 | inferred from direct assay CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 CCR4-NOT complex ; GO:0030014 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 "CAF40, CNOT9, Rcd-1, CG14213, Drcd-1, Caf40" "IPR007216:Rcd1/Caf40, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG14213 11-Aug-17 DroID_v2017_08 Drer\rqcd1 Scer\CAF40 Cele\ntl-9 Xtro\rqcd1 Mmus\Cnot9 Hsap\CNOT9 "viable,visible,fertile" trichogen cell DRSC19569 I -1.710208536 2.943346331 -0.416651822 0.870365921 0.278662277 0.345434233 FBgn0053503 Cyp12d1-d Cyp12d1-d http://flybase.org/reports/FBgn0053503 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity ; GO:0030342 | inferred from sequence or structural similarity with UniProtKB:Q07973" response to insecticide ; GO:0017085 | inferred from mutant phenotype response to DDT ; GO:0046680 | inferred from mutant phenotype oxidation-reduction process ; GO:0055114 | inferred from sequence or structural similarity with UniProtKB:Q07973 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9DBG1 "CG18239, Cyp12d2, Cyp12d1, CYP12D1, CT26082, 12d1, 12D1, CG18240, CG33503, Cyp12d1-d, Cyp 12d1, CYP12d1-d" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG33503 11-Aug-17 DroID_v2017_08 "Drer\cyp27b1, Drer\zgc:136333, Drer\si:dkey-91i10.3, Drer\cyp24a1, Drer\si:ch211-113j14.1, Drer\cyp27a7, Drer\cyp27a1.4, Drer\cyp11a2, Drer\cyp27c1, Drer\cyp27a1.2, Drer\cyp11c1" Scer\DIT2 "Cele\cyp-44A1, Cele\ZK177.4" "Xtro\cyp27c1, Xtro\LOC100145331, Xtro\cyp11a1, Xtro\cyp27a1, Xtro\cyp24a1, Xtro\cyp27b1" "Mmus\Cyp24a1, Mmus\Cyp11a1, Mmus\Cyp11b2, Mmus\Cyp27b1, Mmus\Cyp11b1, Mmus\Cyp27a1" "Hsap\CYP27C1, Hsap\CYP24A1, Hsap\CYP27B1, Hsap\CYP11A1, Hsap\CYP27A1, Hsap\CYP11B1, Hsap\CYP11B2" chemical resistant FBgn0027504 CG8878 - http://flybase.org/reports/FBgn0027504 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein kinase activity ; GO:0004672 | non-traceable author statement" "regulation of gene expression, epigenetic ; GO:0040029 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 "VRK, BcDNA:LD23371, CG8878" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG8878 11-Aug-17 DroID_v2017_08 "Drer\csnk1da, Drer\vrk3, Drer\vrk2, Drer\ttbk1b, Drer\csnk1a1, Drer\ttbk2b, Drer\csnk1db, Drer\ttbk1a, Drer\vrk1, Drer\csnk1e" "Scer\YCK2, Scer\HRR25, Scer\YCK1, Scer\YCK3" "Cele\F16B12.7, Cele\C50F4.10, Cele\E02H4.6, Cele\vrk-1, Cele\C44C10.7, Cele\C28A5.6, Cele\K09C6.7, Cele\ZK354.6, Cele\K08H2.5, Cele\prde-1, Cele\K04C1.5, Cele\F41G3.5, Cele\K09C6.8, Cele\ZK666.8" "Xtro\csnk1a1, Xtro\ttbk2, Xtro\csnk1d, Xtro\vrk1, Xtro\vrk2, Xtro\csnk1e, Xtro\vrk3" "Mmus\Vrk3, Mmus\Csnk1a1, Mmus\Ttbk1, Mmus\Csnk1e, Mmus\Csnk1d, Mmus\Vrk2, Mmus\Ttbk2, Mmus\Vrk1" "Hsap\CSNK1E, Hsap\VRK2, Hsap\TTBK1, Hsap\VRK3, Hsap\CSNK1D, Hsap\CSNK1A1, Hsap\TTBK2, Hsap\VRK1, Hsap\CSNK1A1L" "fertile,viable,visible" "trichogen cell,mesothoracic tergum" DRSC05953 I -0.778155799 -1.884819853 -0.118305453 -0.648595662 -0.496772042 0.00251685 FBgn0031450 Hrs Hepatocyte growth factor regulated tyrosine kinase substrate http://flybase.org/reports/FBgn0031450 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 ubiquitin binding ; GO:0043130 | inferred from direct assay ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000005289 "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002014 positive regulation of fibroblast growth factor receptor signaling pathway ; GO:0045743 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from genetic interaction with Stam regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype membrane protein proteolysis ; GO:0033619 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with l(2)gd1 torso signaling pathway ; GO:0008293 | non-traceable author statement endosomal transport ; GO:0016197 | traceable author statement endosomal transport ; GO:0016197 | inferred from mutant phenotype endocytosis ; GO:0006897 | non-traceable author statement positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype vesicle organization ; GO:0016050 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle priming ; GO:0016082 | non-traceable author statement torso signaling pathway ; GO:0008293 | inferred from mutant phenotype positive regulation of protein ubiquitination ; GO:0031398 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000005289 negative regulation of protein phosphorylation ; GO:0001933 | inferred from direct assay endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype exosomal secretion ; GO:1990182 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity neuron remodeling ; GO:0016322 | inferred from genetic interaction with Stam negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | non-traceable author statement exocytosis ; GO:0006887 | traceable author statement" ESCRT-0 complex ; GO:0033565 | inferred from sequence or structural similarity with SGD:S000005289 synaptic vesicle ; GO:0008021 | non-traceable author statement ESCRT-0 complex ; GO:0033565 | inferred from direct assay endosome ; GO:0005768 | traceable author statement "HRS, hrs, CG2903, l(2)23Ad, HRS-2, l(2)23AB5, Hrs, vps27, l(2)23Ad(Hrs), Vps27, DmHRS, dHrs" "IPR000306:FYVE zinc finger, IPR002014:VHS domain, IPR003903:Ubiquitin interacting motif, IPR008942:ENTH/VHS, IPR011011:Zinc finger, FYVE/PHD-type, IPR017073:Ubiquitin binding protein, Hrs/VPS27, IPR017455:Zinc finger, FYVE-related, IPR024641:Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2903 11-Aug-17 DroID_v2017_08 "Drer\hgs, Drer\si:ch211-11n16.2, Drer\zfyve1, Drer\gga1, Drer\zfyve19, Drer\tom1l2" "Scer\GGA1, Scer\VPS27, Scer\GGA2" "Cele\apt-9, Cele\C07A12.7, Cele\hgrs-1" "Xtro\zfyve1, Xtro\hgs, Xtro\tom1l2, Xtro\zfyve19" "Mmus\Tom1l2, Mmus\Gga1, Mmus\Gga2, Mmus\Zfyve19, Mmus\Gga3, Mmus\Hgs, Mmus\Zfyve1" "Hsap\ZFYVE19, Hsap\GGA1, Hsap\GGA3, Hsap\TOM1L2, Hsap\ZFYVE1, Hsap\HGS, Hsap\GGA2" "neuroanatomy defective,lethal,increased cell size,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,recessive,some die during larval stage,visible,partially lethal - majority die" "glial cell,eye disc,endosome,eye,somatic clone,photoreceptor cell,imaginal disc epithelial cell,late endosome | somatic clone,eye-antennal disc,border follicle cell,oocyte,vesicle,embryonic/larval garland cell,eye photoreceptor cell,wing margin,wing,wing margin bristle,chaeta,supernumerary,mesothoracic tergum" FBgn0034887 St1 Sulfotransferase 1 http://flybase.org/reports/FBgn0034887 protein_coding_gene sulfotransferase activity ; GO:0008146 | inferred from direct assay xenobiotic metabolic process ; GO:0006805 | inferred from direct assay sulfation ; GO:0051923 | inferred from direct assay cytosol ; GO:0005829 | non-traceable author statement "dmST1, St1, CG5428, st1" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000863:Sulfotransferase domain" CG5428 11-Aug-17 DroID_v2017_08 "Drer\sult2st1, Drer\sult1st5, Drer\sult3st2, Drer\sult3st3, Drer\sult5a1, Drer\si:dkey-236e20.3, Drer\sult1st8, Drer\sult1st6, Drer\sult1st3, Drer\sult1st2, Drer\sult3st4, Drer\sult2st3, Drer\sult1st1, Drer\sult4a1, Drer\sult1st4, Drer\sult6b1, Drer\sult3st1, Drer\sult1st7, Drer\sult2st2" - Cele\ssu-1 "Xtro\sult4a1, Xtro\LOC779590, Xtro\sult6b1, Xtro\sult1e1, Xtro\LOC100497264, Xtro\LOC496998, Xtro\sult1a1, Xtro\sult2b1, Xtro\sult1c2" "Mmus\Sult4a1, Mmus\Sult1e1, Mmus\Sult3a2, Mmus\Sult2a7, Mmus\Sult2a1, Mmus\Sult1b1, Mmus\Sult1d1, Mmus\Sult2a3, Mmus\Sult2b1, Mmus\Sult2a2, Mmus\Sult1a1, Mmus\Sult5a1, Mmus\Sult2a8, Mmus\Sult2a6, Mmus\Sult6b1, Mmus\Sult1c1, Mmus\Sult1c2, Mmus\Sult3a1, Mmus\Sult6b2, Mmus\Sult2a4, Mmus\Sult2a5" "Hsap\SULT1A3, Hsap\SULT1C2, Hsap\SULT6B1, Hsap\SULT1E1, Hsap\SULT2A1, Hsap\SULT1A4, Hsap\SULT1A2, Hsap\SULT2B1, Hsap\SULT4A1, Hsap\SULT1B1, Hsap\SULT1C3, Hsap\SULT1C4, Hsap\SULT1A1" "viable,visible" trichogen cell FBgn0004117 Tm2 Tropomyosin 2 http://flybase.org/reports/FBgn0004117 "FBgn0002442, FBgn0003722, FBgn0003724, FBgn0026830" protein_coding_gene actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000443979 actin binding ; GO:0003779 | inferred from sequence or structural similarity structural constituent of muscle ; GO:0008307 | inferred from biological aspect of ancestor with PANTHER:PTN001059856 actin filament organization ; GO:0007015 | inferred from biological aspect of ancestor with PANTHER:PTN000443979 muscle contraction ; GO:0006936 | inferred from biological aspect of ancestor with PANTHER:PTN001059856 positive regulation of sarcomere organization ; GO:0060298 | inferred from genetic interaction with hoip heart development ; GO:0007507 | inferred from mutant phenotype muscle thin filament tropomyosin ; GO:0005862 | inferred from biological aspect of ancestor with PANTHER:PTN001059856 actin filament ; GO:0005884 | inferred from biological aspect of ancestor with PANTHER:PTN000443979 "Tm, Tm2, l(3)nc99Eb, CG4843, DROTROPI1, TmI, Tm1, Ifm(3)3, Tn-H, Ifm-TmI, dro Tm, mTmI, Ifm(3)5, Tm127, TM2, TmII, IP16005p" IPR000533:Tropomyosin CG4843 11-Aug-17 DroID_v2017_08 "Drer\tpm2, Drer\tpm4b, Drer\tpm4a, Drer\tpm1, Drer\tpm3, Drer\tpma" "Scer\EDE1, Scer\TPM2, Scer\TPM1" "Cele\lev-11, Cele\Y45F10B.9" "Xtro\tpm4, Xtro\tpm2, Xtro\tpm1" "Mmus\Tpm4, Mmus\Tpm3, Mmus\Tpm1, Mmus\Tpm2" "Hsap\TPM3, Hsap\TPM4, Hsap\TPM1, Hsap\TPM2" " adult stage , embryonic stage | late , pupal stage " " leg

, adult thorax

" "flightless,semidominant,viable,dominant,wild-type,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,flight defective,visible" "adult heart chamber,adult heart,myofibril,indirect flight muscle,embryonic/larval heart,trichogen cell" FBgn0038286 CG6966 - http://flybase.org/reports/FBgn0038286 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with UniProtKB:Q9UK73 regulation of ubiquitin-protein transferase activity ; GO:0051438 | inferred from sequence or structural similarity with UniProtKB:Q9UK73 - "BcDNA:AT05246, CG6966" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG6966 11-Aug-17 DroID_v2017_08 "Drer\ankrd33ab, Drer\fem1b, Drer\fem1a, Drer\ankrd33aa, Drer\ankrd46b, Drer\fem1c" - Cele\fem-1 "Xtro\fem1b, Xtro\fem1c" "Mmus\Ankrd46, Mmus\Fem1c, Mmus\Fem1b, Mmus\Fem1a, Mmus\Ankrd33, Mmus\4931440F15Rik" "Hsap\FEM1B, Hsap\ANKRD46, Hsap\LONRF2, Hsap\FEM1C, Hsap\FEM1A" viable FBgn0039085 CG10170 - http://flybase.org/reports/FBgn0039085 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG10170 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG10170 11-Aug-17 DroID_v2017_08 "Drer\ugt2a2, Drer\ugt5b1, Drer\ugt2b3, Drer\ugt1b4, Drer\ugt5g2, Drer\ugt2a6, Drer\ugt1b3, Drer\ugt5e1, Drer\ugt5b2, Drer\ugt5a2, Drer\ugt1b5, Drer\ugt5b3, Drer\ugt5c2, Drer\ugt2a5, Drer\ugt5c1, Drer\ugt2b6, Drer\ugt5b6, Drer\ugt5d1, Drer\ugt5a1, Drer\ugt8, Drer\ugt5f1, Drer\ugt5a5, Drer\ugt5g1, Drer\ugt1b2, Drer\ugt5c3, Drer\ugt5b4, Drer\ugt1ab, Drer\ugt1b7, Drer\zgc:172315, Drer\ugt2b1, Drer\ugt2b5, Drer\ugt5a4" Scer\ATG26 "Cele\ugt-39, Cele\ugt-12, Cele\ugt-16, Cele\ugt-41, Cele\ugt-48, Cele\ugt-54, Cele\ugt-13, Cele\ugt-11, Cele\C03A7.12, Cele\F10D2.8, Cele\ugt-6, Cele\ugt-7, Cele\ugt-18, Cele\ugt-4, Cele\ugt-14, Cele\ugt-38, Cele\ugt-33, Cele\ugt-51, Cele\ugt-8, Cele\K04A8.10, Cele\ugt-25, Cele\Y43D4A.2, Cele\ugt-61, Cele\ugt-30, Cele\H23N18.4, Cele\ugt-1, Cele\C23G10.6, Cele\ugt-49, Cele\ugt-60, Cele\C55H1.1, Cele\ugt-53, Cele\ugt-21, Cele\ugt-44, Cele\ugt-9, Cele\ugt-34, Cele\ugt-31, Cele\ugt-59, Cele\F54C1.1, Cele\ugt-26, Cele\ugt-50, Cele\ugt-47, Cele\ugt-36, Cele\ugt-65, Cele\ugt-35, Cele\ugt-55, Cele\ugt-2, Cele\ugt-15, Cele\ugt-5, Cele\C03A7.13, Cele\ugt-29, Cele\ugt-19, Cele\ugt-45, Cele\ugt-17, Cele\ugt-42, Cele\ugt-23, Cele\ugt-28, Cele\ugt-24, Cele\ugt-3, Cele\ugt-22, Cele\ugt-32, Cele\ugt-40, Cele\ugt-27, Cele\ugt-46, Cele\ugt-58, Cele\ugt-20, Cele\ugt-52, Cele\ugt-56, Cele\ugt-43, Cele\ugt-37, Cele\ugt-62, Cele\ugt-10" "Xtro\ugt2b4, Xtro\ugt8, Xtro\ugt2a1, Xtro\ugt1a6, Xtro\ugt3a2" "Mmus\Ugt2b35, Mmus\Ugt3a2, Mmus\Ugt2b5, Mmus\Ugt8a, Mmus\Ugt1a7c, Mmus\Ugt2a1, Mmus\Ugt1a2, Mmus\Ugt1a5, Mmus\Ugt1a1, Mmus\Ugt2b37, Mmus\Ugt1a9, Mmus\Ugt2b1, Mmus\Ugt2a3, Mmus\Ugt2b36, Mmus\Ugt1a6b, Mmus\Ugt2b38, Mmus\Ugt2b34, Mmus\Ugt3a1" "Hsap\UGT2A2, Hsap\UGT1A4, Hsap\UGT1A10, Hsap\UGT3A2, Hsap\UGT8, Hsap\UGT2B17, Hsap\UGT1A9, Hsap\UGT1A5, Hsap\UGT2B15, Hsap\UGT2B11, Hsap\UGT1A1, Hsap\UGT2B7, Hsap\UGT1A8, Hsap\UGT2B28, Hsap\UGT1A6, Hsap\UGT2B4, Hsap\UGT3A1, Hsap\UGT1A3, Hsap\UGT2B10, Hsap\UGT2A3, Hsap\UGT1A7" viable DRSC26386 K -0.744775119 -0.592392884 -0.117209462 -0.296797189 3.832767986 0.866394865 FBgn0017590 klg klingon http://flybase.org/reports/FBgn0017590 "FBgn0011803, FBgn0015947" protein_coding_gene - "long-term memory ; GO:0007616 | inferred from mutant phenotype R7 cell fate commitment ; GO:0007465 | inferred from genetic interaction with Sos, sev olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay anesthesia-resistant memory ; GO:0007615 | NOT inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype" extrinsic component of plasma membrane ; GO:0019897 | inferred from sequence or structural similarity "Klg, CG6669, CT20712, l(3)rN712, h214, klg" "IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003599:Immunoglobulin subtype" CG6669 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-250k15.10, Drer\si:zfos-1011f11.1, Drer\gpa33, Drer\jam2b, Drer\si:dkey-65b12.12, Drer\mxra8a, Drer\negr1, Drer\jam3a, Drer\zgc:153073, Drer\opcml, Drer\esama, Drer\cxcr3.1, Drer\mxra8b, Drer\cxadr, Drer\igsf11, Drer\ntm, Drer\jam3b, Drer\zgc:110372, Drer\esamb, Drer\vsig8b, Drer\jam2a, Drer\vsig8a, Drer\f11r.1, Drer\f11r.2" - "Cele\rig-5, Cele\wrk-1" "Xtro\negr1, Xtro\ntm, Xtro\lsamp" "Mmus\Jam3, Mmus\Ntm, Mmus\Igsf5, Mmus\Opcml, Mmus\Negr1, Mmus\Esam, Mmus\Gm1123, Mmus\Cxadr, Mmus\Lsamp, Mmus\Hepacam2, Mmus\F11r, Mmus\Gpa33, Mmus\Iglon5, Mmus\Fgfrl1, Mmus\Vsig2, Mmus\Vsir, Mmus\Jam2, Mmus\Vsig8, Mmus\Clmp, Mmus\Vsig1, Mmus\Mxra8, Mmus\Igsf11" "Hsap\IGSF5, Hsap\CXADR, Hsap\IGSF11, Hsap\C10orf54, Hsap\JAM3, Hsap\LSAMP, Hsap\IGLON5, Hsap\GPA33, Hsap\ESAM, Hsap\F11R, Hsap\MXRA8, Hsap\VSIG1, Hsap\CLMP, Hsap\NEGR1, Hsap\JAM2, Hsap\VSIG2, Hsap\C1orf204, Hsap\OPCML, Hsap\NTM, Hsap\VSIG8" " pupal stage , embryonic stage | stage >=12 , larval stage | third instar " " photoreceptor cell R8

, neuron

, embryonic peripheral nervous system

, eye disc | restricted

, photoreceptor cell R7

, lamina anlage | restricted

, embryonic central nervous system | restricted

, morphogenetic furrow | posterior to

" "memory defective,recessive,chemical sensitive,lethal,lethal - all die before end of larval stage,some die during larval stage,long lived,viable" "photoreceptor cell,photoreceptor cell R7,ommatidium" DRSC13591 IE -1.639676546 -0.363293613 -2.893383398 -0.563477559 -0.751581179 -0.198196403 FBgn0038047 CG5245 - http://flybase.org/reports/FBgn0038047 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "anon-WO0118547.611, CG5245" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5245 11-Aug-17 DroID_v2017_08 "Drer\prdm1c, Drer\gtf3aa" "Scer\AZF1, Scer\STP3, Scer\ZAP1, Scer\PZF1, Scer\STP4" "Cele\sma-9, Cele\hinf-1, Cele\sem-4, Cele\Y5F2A.4, Cele\Y48G8AL.10, Cele\Y55F3AM.14, Cele\Y22D7AL.16, Cele\che-1, Cele\row-1, Cele\snai-1, Cele\ztf-14" "Xtro\znf341, Xtro\znf668" "Mmus\Zfp27, Mmus\Zfp111, Mmus\Zbtb40, Mmus\Zkscan14, Mmus\Zfp719, Mmus\Zfp146, Mmus\Zfp970, Mmus\Zfp932, Mmus\Gtf3a, Mmus\Zfp263, Mmus\Zfp612, Mmus\Zfp11, Mmus\Zfp872, Mmus\Zfp46, Mmus\Zfp663, Mmus\Zkscan1, Mmus\Gm3604, Mmus\Zfp819, Mmus\Zfp3, Mmus\Zfp236, Mmus\Zfp992, Mmus\Zfp955a, Mmus\Zfp867, Mmus\Zkscan4" "Hsap\ZNF146, Hsap\ZNF195, Hsap\ZNF667, Hsap\ZNF263, Hsap\ZNF436, Hsap\ZNF429, Hsap\ZNF133, Hsap\ZFP90, Hsap\ZNF680, Hsap\ZNF226, Hsap\ZNF497, Hsap\ZNF737, Hsap\ZNF529, Hsap\ZNF483, Hsap\ZNF45, Hsap\ZNF74, Hsap\GTF3A, Hsap\ZNF467, Hsap\REPIN1, Hsap\ZNF275, Hsap\ZNF727, Hsap\ZNF358, Hsap\ZNF699, Hsap\ZSCAN22" "viable,fertile" FBgn0000810 fs(1)K10 female sterile (1) K10 http://flybase.org/reports/FBgn0000810 FBgn0029607 protein_coding_gene DNA binding ; GO:0003677 | inferred from sequence or structural similarity ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement dorsal/ventral pattern formation ; GO:0009953 | traceable author statement negative regulation of translation ; GO:0017148 | traceable author statement pole plasm mRNA localization ; GO:0019094 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype protein localization ; GO:0008104 | traceable author statement nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "K10, CG3218, EG:30B8.5, fs(1)k10, K-10, fs(1)M9, fs(1)K10, k10, f(s)K10" IPR015943:WD40/YVTN repeat-like-containing domain CG3218 11-Aug-17 DroID_v2017_08 - - "Cele\col-146, Cele\col-44" - Mmus\Chtf8 Hsap\CHTF8 " embryonic stage -- adult stage , embryonic stage | early , embryonic stage | female , oogenesis stage && adult stage | female , adult stage && oogenesis stage | female , adult stage | female , embryonic stage | stage 1-13 , adult stage && oogenesis stage " " oocyte

, germarium

, oocyte

{ v BicDr } , organism

, ovary

, oocyte

{ v BicDR26 } , cystoblast

" adult stage && oogenesis stage | stage S8-9 oocyte

"female sterile,wild-type,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,germline clone,non-rescuable maternal effect" "egg,chorion,maternal effect,chorion | germline clone | maternal effect,embryo,dorsal appendage,follicle cell,oocyte,egg chamber,ventral,filzkorper,epidermis,ectopic" FBgn0002872 mu2 mutator 2 http://flybase.org/reports/FBgn0002872 - protein_coding_gene RNA polymerase II transcription coactivator activity ; GO:0001105 | inferred from genetic interaction with Hsap\AR inferred from genetic interaction with Hsap\AR inferred from genetic interaction with Hsap\AR inferred from genetic interaction with Hsap\AR regulation of chromatin organization ; GO:1902275 | inferred from mutant phenotype regulation of chromatin silencing at centromere ; GO:0090052 | inferred from mutant phenotype double-strand break repair ; GO:0006302 | inferred from mutant phenotype "chromosome, centromeric region ; GO:0000775 | inferred from direct assay nuclear euchromatin ; GO:0005719 | inferred from direct assay" "CG1960, mu-2, cDNA D, mutator[2], mu2, MU2, MDC1, Mdc1, Mu2" IPR001357:BRCT domain CG1960 11-Aug-17 DroID_v2017_08 "Drer\paxip1, Drer\mdc1" Scer\RTT107 - Xtro\paxip1 "Mmus\Mdc1, Mmus\Paxip1" "Hsap\PAXIP1, Hsap\MDC1" " embryonic stage , adult stage | female && oogenesis stage | stage S5-6 , adult stage && oogenesis stage | stage >=S8 , adult stage && oogenesis stage , larval stage , embryonic stage -- adult stage , embryonic stage | early " " embryonic central nervous system

, oocyte | posterior

, oocyte | anterior

, germarium

, larval brain

,

ubiquitous , eye disc

, morphogenetic furrow

, oocyte

, imaginal disc

" "viable,fertile,wild-type,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0259937 Nop60B Nucleolar protein at 60B http://flybase.org/reports/FBgn0259937 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002478, InterPro:IPR020103 pseudouridine synthase activity ; GO:0009982 | inferred from biological aspect of ancestor with PANTHER:PTN000565614" rRNA processing ; GO:0006364 | inferred from mutant phenotype pseudouridine synthesis ; GO:0001522 | inferred from mutant phenotype ribosome biogenesis ; GO:0042254 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype mRNA pseudouridine synthesis ; GO:1990481 | inferred from biological aspect of ancestor with PANTHER:PTN000565614 box H/ACA snoRNA 3'-end processing ; GO:0000495 | inferred from biological aspect of ancestor with PANTHER:PTN000565614 wing disc development ; GO:0035220 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern snRNA pseudouridine synthesis ; GO:0031120 | inferred from biological aspect of ancestor with PANTHER:PTN000565614 rRNA pseudouridine synthesis ; GO:0031118 | inferred from biological aspect of ancestor with PANTHER:PTN000565614 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay box H/ACA snoRNP complex ; GO:0031429 | inferred from biological aspect of ancestor with PANTHER:PTN000565614 "CG3333, Nop60b, Nop60B, mfl, FBgn0023184, nop60B, l(2)k05318, Uhg6, dUhg6, Nop60, MFL/Nop60B, CG333, minifly, Nop60B/mfl, Nop60B/mnf" "IPR015947:PUA-like domain, IPR002478:PUA domain, IPR002501:Pseudouridine synthase II, N-terminal, IPR004802:tRNA pseudouridine synthase B family, IPR012960:Dyskerin-like, IPR032819:tRNA pseudouridylate synthase B, C-terminal, IPR020103:Pseudouridine synthase, catalytic domain" CG3333 11-Aug-17 DroID_v2017_08 "Drer\trub1, Drer\dkc1" "Scer\CBF5, Scer\PUS4" Cele\K01G5.5 "Xtro\dkc1, Xtro\trub1" "Mmus\Dkc1, Mmus\Trub1" "Hsap\DKC1, Hsap\TRUB1" " embryonic stage | stage 4-14 , adult stage && oogenesis stage , embryonic stage , embryonic stage&&larval stage , embryonic stage -- adult stage , oogenesis stage , embryonic stage | 0-4 hr , adult stage | female , oogenesis stage | stage >=S3 && adult stage | female , embryonic stage | 0-6 hr , embryonic stage | 0-4hr " "

ubiquitous , nurse cell

, ovary

ubiquitous , oocyte

, ovary

" " adult stage && oogenesis stage , oogenesis stage , embryonic stage " " germarium

,

ubiquitous , follicle cell

, ovary

" FBgn0264307 orb2 orb2 http://flybase.org/reports/FBgn0264307 protein_coding_gene "translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from mutant phenotype mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay translation activator activity ; GO:0008494 | inferred from mutant phenotype RNA binding ; GO:0003723 | non-traceable author statement translation factor activity, RNA binding ; GO:0008135 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VXJ9 ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA binding ; GO:0003723 | inferred from sequence model translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from direct assay" long-term memory ; GO:0007616 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay positive regulation of translation ; GO:0045727 | inferred from direct assay spermatogenesis ; GO:0007283 | inferred from mutant phenotype male meiosis I ; GO:0007141 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype negative regulation of cytoplasmic translation ; GO:2000766 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 sperm individualization ; GO:0007291 | inferred from mutant phenotype synaptic membrane ; GO:0097060 | inferred from direct assay axon terminus ; GO:0043679 | inferred from direct assay dendrite terminus ; GO:0044292 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 cell body ; GO:0044297 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay messenger ribonucleoprotein complex ; GO:1990124 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 "orb2, CG5735, CG43113, anon-WO0140519.222, Orb2, cg5735, CG43782" "IPR000504:RNA recognition motif domain, IPR032296:Cytoplasmic polyadenylation element-binding protein, ZZ domain" CG43782 11-Aug-17 DroID_v2017_08 "Drer\cpeb2, Drer\cpeb4, Drer\cpeb3, Drer\cpeb1a, Drer\tex2, Drer\tex2l" Scer\NVJ2 "Cele\fog-1, Cele\cpb-1, Cele\cpb-3, Cele\cpb-2, Cele\F55C12.5" "Xtro\cpeb2, Xtro\cpeb4, Xtro\cpeb1, Xtro\cpeb3" "Mmus\Cpeb2, Mmus\Tex2, Mmus\Cpeb4, Mmus\Cpeb1, Mmus\Cpeb3" "Hsap\TEX2, Hsap\CPEB4, Hsap\CPEB2, Hsap\CPEB3" FBgn0027945 ppl pumpless http://flybase.org/reports/FBgn0027945 protein_coding_gene - glycine decarboxylation via glycine cleavage system ; GO:0019464 | inferred from electronic annotation with InterPro:IPR017453 glycine catabolic process ; GO:0006546 | inferred from sequence or structural similarity with UniProtKB:P23434 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P23434 glycine cleavage complex ; GO:0005960 | inferred from sequence or structural similarity with UniProtKB:P23434 "CG7758, l(3)78Cb, l(3)00217, ppl" "IPR002930:Glycine cleavage system H-protein, IPR003016:2-oxo acid dehydrogenase, lipoyl-binding site, IPR011053:Single hybrid motif, IPR017453:Glycine cleavage system H-protein, subgroup, IPR033753:Glycine cleavage system H-protein/Simiate, IPR000089:Biotin/lipoyl attachment" CG7758 11-Aug-17 DroID_v2017_08 "Drer\gcshb, Drer\gcsha" Scer\GCV3 "Cele\F52A8.5, Cele\gcsh-1" Xtro\gcsh Mmus\Gcsh Hsap\GCSH " embryonic stage&&larval stage , embryonic stage | stage 15-17 " " embryonic/larval fat body

, embryonic fat body

, larval fat body

" "lethal,recessive,feeding behavior defective,lethal - all die before end of larval stage,some die during larval stage,wild-type,viable,visible" "embryonic/larval pharynx,embryonic/larval digestive system,trichogen cell" FBgn0036698 CG7724 - http://flybase.org/reports/FBgn0036698 protein_coding_gene 3-beta-hydroxy-delta5-steroid dehydrogenase activity ; GO:0003854 | inferred from electronic annotation with InterPro:IPR002225 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002225 steroid biosynthetic process ; GO:0006694 | inferred from electronic annotation with InterPro:IPR002225 - CG7724 "IPR016040:NAD(P)-binding domain, IPR002225:3-beta hydroxysteroid dehydrogenase/isomerase" CG7724 11-Aug-17 DroID_v2017_08 "Drer\nsdhl, Drer\hsd3b7, Drer\sdr42e2, Drer\hsd3b1, Drer\sdr42e1, Drer\hsd3b2" Scer\ERG26 "Cele\hsd-3, Cele\hsd-1, Cele\perm-1, Cele\hsd-2, Cele\C32D5.12" "Xtro\LOC100490622, Xtro\hsd3b7, Xtro\LOC100494546, Xtro\nsdhl, Xtro\sdr42e1" "Mmus\Hsd3b4, Mmus\Nsdhl, Mmus\Hsd3b7, Mmus\Sdr42e1, Mmus\Hsd3b5, Mmus\Gm10681, Mmus\Hsd3b1, Mmus\Hsd3b6, Mmus\Gm4450, Mmus\Hsd3b2, Mmus\Hsd3b3" "Hsap\SDR42E2, Hsap\HSD3B2, Hsap\HSD3B1, Hsap\SDR42E1, Hsap\HSD3B7, Hsap\NSDHL" lethal FBgn0052706 CG32706 - http://flybase.org/reports/FBgn0052706 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000480 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 small-subunit processome assembly ; GO:0034462 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000472 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 CG32706 "IPR000504:RNA recognition motif domain, IPR034353:ABT1/ESF2, RNA recognition motif" CG32706 11-Aug-17 DroID_v2017_08 Drer\abt1 Scer\ESF2 Cele\F57B10.8 Xtro\abt1 Mmus\Abt1 Hsap\ABT1 FBgn0039862 kek6 kek6 http://flybase.org/reports/FBgn0039862 protein_coding_gene - negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | NOT inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000757746 "CG1804, kek6" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR003599:Immunoglobulin subtype" CG1804 11-Aug-17 DroID_v2017_08 "Drer\zgc:153913, Drer\nyx, Drer\LOC101882074, Drer\lrrc32, Drer\rtn4r, Drer\lrtm2b, Drer\lrit1a, Drer\islr2, Drer\slitrk5b, Drer\rtn4rl1b, Drer\lrrc24, Drer\lrit3a, Drer\lrtm1, Drer\lrtm2a, Drer\lrit3b, Drer\lrrc38b, Drer\si:dkey-100n23.3, Drer\slitrk3b, Drer\si:dkey-52j6.3, Drer\lrit1b, Drer\lrrc38a, Drer\lrrc9, Drer\lrit2" - "Cele\iglr-3, Cele\lron-15, Cele\C06A8.6, Cele\pxn-1" "Xtro\lrit3, Xtro\lrrc15, Xtro\lrtm2, Xtro\lrit2, Xtro\lrrc52, Xtro\rtn4r, Xtro\islr2, Xtro\slitrk6, Xtro\lrrc24, Xtro\slitrk3" "Mmus\Lrtm2, Mmus\Slitrk5, Mmus\Islr2, Mmus\Lrtm1, Mmus\Lrrc52, Mmus\Lrrc38, Mmus\Cpn2, Mmus\Lrrc55, Mmus\Islr, Mmus\Tril, Mmus\Slitrk2, Mmus\Lrrc24, Mmus\Slitrk1, Mmus\Lrit3, Mmus\Lrit2, Mmus\Lrrn4, Mmus\Rtn4r, Mmus\Lrit1, Mmus\Lrrc26, Mmus\Lrrc32, Mmus\Slitrk6" "Hsap\LRFN2, Hsap\LRIT1, Hsap\RTN4R, Hsap\LRFN5, Hsap\LRTM2, Hsap\LRFN3, Hsap\SLITRK1, Hsap\LRRC55, Hsap\LRRC52, Hsap\SLITRK2, Hsap\ISLR2, Hsap\LRFN1, Hsap\LRRC38, Hsap\LRIT2, Hsap\ISLR, Hsap\LRRC32, Hsap\LRRC26, Hsap\SLITRK6, Hsap\LRRC24, Hsap\LRTM1, Hsap\LRFN4, Hsap\SLITRK5, Hsap\LRIT3" "visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,viable" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0026192 par-6 par-6 http://flybase.org/reports/FBgn0026192 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with sdt "phagocytosis ; GO:0006909 | inferred from mutant phenotype establishment or maintenance of neuroblast polarity ; GO:0045196 | non-traceable author statement positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype establishment of neuroblast polarity ; GO:0045200 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype zonula adherens assembly ; GO:0045186 | non-traceable author statement cell adhesion ; GO:0007155 | inferred from mutant phenotype apical protein localization ; GO:0045176 | non-traceable author statement establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | non-traceable author statement oocyte axis specification ; GO:0007309 | traceable author statement establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | traceable author statement branching involved in open tracheal system development ; GO:0060446 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from mutant phenotype zonula adherens assembly ; GO:0045186 | traceable author statement positive regulation of lamellipodium assembly ; GO:0010592 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of protein kinase activity ; GO:0006469 | inferred from direct assay establishment or maintenance of polarity of embryonic epithelium ; GO:0016332 | non-traceable author statement terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with mts germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype morphogenesis of a polarized epithelium ; GO:0001738 | traceable author statement" cell cortex ; GO:0005938 | traceable author statement apical cortex ; GO:0045179 | non-traceable author statement subapical complex ; GO:0035003 | traceable author statement muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay apical plasma membrane ; GO:0016324 | traceable author statement terminal bouton ; GO:0043195 | inferred from direct assay "Par-6, par-6, Par6, DmPar-6, DmPAR-6, DmPar6, PAR6, par6, Dmpar6, dPar-6, DPar6, DPar-6, par, Dm-Par-6, dPAR-6, dmPar-6, CG5884, Par, PAR-6, Dm-Par6" "IPR000270:PB1 domain, IPR001478:PDZ domain" CG5884 11-Aug-17 DroID_v2017_08 "Drer\pard6b, Drer\pard6gb, Drer\pard6a, Drer\pard6ga" - "Cele\par-6, Cele\C09G1.4" "Xtro\pard6g, Xtro\pard6b" "Mmus\Mpp3, Mmus\Pard6b, Mmus\Pard6g, Mmus\Pard6a" "Hsap\PARD6G, Hsap\PARD6B, Hsap\WHRN, Hsap\PARD6A" pupal stage photoreceptor cell stalk | apical

"lethal,recessive,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,visible" "border follicle cell,border follicle cell & filopodium | ectopicslbo.2.6, upd.PU,terminal tracheal cell,somatic clone,embryonic/larval cuticle,embryonic head,epithelial cell,germline clone,embryonic neuroblast,embryonic/first instar larval cuticle,egg chamber,oocyte,follicle cell,bouton,trichogen cell,mesothoracic tergum,epithelium,female germline cyst" FBgn0001215 Hrb98DE Heterogeneous nuclear ribonucleoprotein at 98DE http://flybase.org/reports/FBgn0001215 "FBgn0003056, FBgn0014945" protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA 5'-UTR binding ; GO:0048027 | inferred from direct assay "female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with HGNC:2549 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype negative regulation of RNA splicing ; GO:0033119 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | inferred from mutant phenotype" intracellular ribonucleoprotein complex ; GO:0030529 | inferred from sequence or structural similarity with HGNC:5031 inferred from direct assay inferred from physical interaction with sqd nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay "Hrb98DE, hrb98DE, CG9983, HRB98DE/hrp38, hrp38, HDP(P9), E7Delta6, p9, anon-E7Delta6, Pen9, Hrb1, Hrb98 de, hrb98 de, HRB98DE, Hrp38, hnRNP A2/B1, Hrb98DE/Hrp38" IPR000504:RNA recognition motif domain CG9983 11-Aug-17 DroID_v2017_08 "Drer\hnrnpa1b, Drer\eif4h, Drer\srsf10a, Drer\msi2b, Drer\hnrnpa0a, Drer\cirbpa, Drer\rbm34, Drer\dazl, Drer\trnau1apb, Drer\hnrnpa0l, Drer\dazap1, Drer\hnrnpd, Drer\ncoa5, Drer\hnrnpa1a, Drer\eif4ba, Drer\zgc:55733, Drer\trnau1apa, Drer\hnrnpabb, Drer\hnrnpaba, Drer\hnrpdl, Drer\raly, Drer\msi2a, Drer\hnrnpa3, Drer\zcrb1, Drer\wu:fq32h04, Drer\hnrnpc, Drer\hnrnpa0b" "Scer\HRP1, Scer\NGR1, Scer\NAM8, Scer\CWC2, Scer\MUD1, Scer\MRN1, Scer\NAB6, Scer\NOP12, Scer\NOP6" "Cele\hrp-1, Cele\H28G03.1, Cele\msi-1" "Xtro\ralyl, Xtro\hnrnpc, Xtro\hnrnpa1, Xtro\hnrnpdl, Xtro\hnrnpa0, Xtro\hnrnpa3, Xtro\hnrnpa2b1, Xtro\dazl, Xtro\trnau1ap, Xtro\rbm34, Xtro\hnrnpd, Xtro\eif4h, Xtro\dazap1, Xtro\cirbp, Xtro\eif4b, Xtro\msi1, Xtro\raly, Xtro\hnrnpab" "Mmus\Dazap1, Mmus\Rbm34, Mmus\Eif4b, Mmus\Zcrb1, Mmus\Cirbp, Mmus\Srsf12, Mmus\Trnau1ap, Mmus\Srsf10, Mmus\Msi2, Mmus\Msi1, Mmus\Gm21379, Mmus\Hnrnpa2b1, Mmus\Raly, Mmus\Rbm31y, Mmus\Hnrnpab, Mmus\Slirp, Mmus\Hnrnpc, Mmus\Hnrnpd, Mmus\Hnrnpdl, Mmus\Dazl, Mmus\Boll, Mmus\Hnrnpa3, Mmus\Eif4h, Mmus\Hnrnpa1, Mmus\Tra2b, Mmus\Hnrnpa0" "Hsap\DAZAP1, Hsap\SLIRP, Hsap\HNRNPD, Hsap\HNRNPA1L2, Hsap\DAZ3, Hsap\MSI2, Hsap\HNRNPDL, Hsap\RALYL, Hsap\HNRNPA0, Hsap\HNRNPC, Hsap\SRSF10, Hsap\TRNAU1AP, Hsap\DAZ2, Hsap\DAZ4, Hsap\CIRBP, Hsap\HNRNPA2B1, Hsap\RBM34, Hsap\RBM3, Hsap\HNRNPA3, Hsap\MSI1, Hsap\HNRNPA1, Hsap\DAZ1, Hsap\DAZL, Hsap\EIF4H, Hsap\BOLL, Hsap\HNRNPCL1, Hsap\HNRNPAB, Hsap\EIF4B, Hsap\RALY" " pupal stage , oogenesis stage && adult stage | female , embryonic stage | early " ovary

"viable,lethal,fertile,visible,body color defective,planar polarity defective,female semi-sterile,partially lethal - majority die,some die during larval stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum,oocyte,egg chamber,anterior,lateral,female germline stem cell" FBgn0028684 Rpt5 Regulatory particle triple-A ATPase 5 http://flybase.org/reports/FBgn0028684 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | inferred from sequence model TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9549 inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000005643 proteasome regulatory particle ; GO:0005838 | inferred from direct assay cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytoplasm ; GO:0005737 | inferred from direct assay nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" "tbp-1, Rpt5, p50, Tbp1, dRpt5, Dm_Rpt5b, Dm_Rpt5a, DmTBP-1, Pros26S-RS6A, l(3)04210, BcDNA.GH12068, Pros26S, CG10370, BcDNA:GH12068, anon-WO0153538.10, anon-WO0153538.9, anon-WO0153538.8, Tbp-1, TBP-1, S6'" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10370 11-Aug-17 DroID_v2017_08 Drer\psmc3 Scer\RPT5 Cele\rpt-5 Xtro\psmc3 Mmus\Psmc3 Hsap\PSMC3 "lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive" DRSC16842 IEK -1.856344141 -4.440338936 -3.623261681 -5.72668481 -0.616425886 -3.092182833 FBgn0036811 MED11 Mediator complex subunit 11 http://flybase.org/reports/FBgn0036811 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from electronic annotation with InterPro:IPR019404 RNA polymerase II transcription cofactor activity ; GO:0001104 | contributes_to inferred by curator from GO:0016592 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 inferred from physical interaction with UniProtKB:Q9VEC1 transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity with HGNC:11473 muscle organ development ; GO:0007517 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with HGNC:11473 mediator complex ; GO:0016592 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Med11, Med21, CG6884, dMED21, BcDNA:GH01072, anon-WO0153538.71, MED11, med11" "IPR019404:Mediator complex, subunit Med11" CG6884 11-Aug-17 DroID_v2017_08 Drer\med11 - Cele\mdt-11 Xtro\med11 Mmus\Med11 Hsap\MED11 lethal DRSC23091 K 2.643702718 2.254138702 FBgn0053901 His4:CG33901 His4:CG33901 http://flybase.org/reports/FBgn0053901 protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 "nucleosome assembly ; GO:0006334 | inferred from direct assay DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleosome ; GO:0000786 | inferred from direct assay nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33901, His4:CG33901" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33901 11-Aug-17 DroID_v2017_08 "Drer\LOC100331412, Drer\zgc:163040, Drer\LOC100329358, Drer\zgc:194989, Drer\si:dkey-261m9.17, Drer\hist1h4l, Drer\LOC570405, Drer\si:dkey-23a13.7, Drer\zgc:154164, Drer\si:dkey-108k21.19, Drer\LOC794549, Drer\si:dkey-108k21.28, Drer\LOC100150038, Drer\si:ch73-36p18.3, Drer\LOC562770, Drer\si:ch211-113a14.26, Drer\si:dkey-261m9.18, Drer\si:ch211-113a14.17, Drer\zgc:153409, Drer\si:ch211-113a14.6, Drer\si:ch73-368j24.1, Drer\si:ch73-36p18.4, Drer\si:dkey-108k21.12, Drer\si:ch73-368j24.14" "Scer\HHF2, Scer\HHF1" "Cele\his-26, Cele\his-50, Cele\his-46, Cele\his-67, Cele\his-31, Cele\his-38, Cele\his-1, Cele\his-5, Cele\his-18, Cele\his-60, Cele\his-14, Cele\his-37, Cele\his-64, Cele\his-28, Cele\his-56, Cele\his-10" "Xtro\LOC101734891, Xtro\hist1h4c, Xtro\hist1h4k, Xtro\LOC100493041" "Mmus\Hist2h4, Mmus\Hist1h4b, Mmus\Hist4h4, Mmus\Hist1h4k, Mmus\Hist1h4d, Mmus\Hist1h4c, Mmus\Hist1h4n, Mmus\Hist1h4a, Mmus\Hist1h4j, Mmus\Hist1h4h, Mmus\Hist1h4f, Mmus\Hist1h4m, Mmus\Hist1h4i" "Hsap\HIST1H4D, Hsap\HIST1H4F, Hsap\HIST1H4G, Hsap\HIST1H4I, Hsap\HIST1H4L, Hsap\HIST1H4B, Hsap\HIST4H4, Hsap\HIST1H4E, Hsap\HIST1H4A, Hsap\HIST1H4J, Hsap\HIST2H4B, Hsap\HIST1H4K, Hsap\HIST1H4H, Hsap\HIST1H4C, Hsap\HIST2H4A" FBgn0053835 His2A:CG33835 His2A:CG33835 http://flybase.org/reports/FBgn0053835 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33835, His2A:CG33835" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33835 11-Aug-17 DroID_v2017_08 "Drer\LOC100148591, Drer\si:ch211-113a14.16, Drer\si:dkey-108k21.19, Drer\si:dkey-261m9.18, Drer\LOC100334934, Drer\si:ch73-368j24.13, Drer\si:ch1073-159d7.11, Drer\si:dkey-23a13.20, Drer\si:ch73-368j24.14, Drer\si:dkey-108k21.26, Drer\si:ch73-36p18.5, Drer\h2afy2, Drer\si:ch211-113a14.26, Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.7, Drer\si:dkey-23a13.14, Drer\zgc:114037, Drer\zgc:101846, Drer\zgc:154164, Drer\si:dkey-261m9.15, Drer\zgc:110434, Drer\si:ch1073-159d7.10, Drer\zgc:195633, Drer\fbxl6, Drer\si:dkey-261m9.7, Drer\si:dkey-261m9.11, Drer\si:dkey-108k21.15, Drer\LOC570115, Drer\zgc:173652, Drer\si:ch211-113a14.11, Drer\si:ch211-113a14.19, Drer\LOC100332229, Drer\h2afx" "Scer\HTA2, Scer\HTA1" "Cele\his-3, Cele\his-61, Cele\his-12, Cele\his-16, Cele\his-35, Cele\his-33, Cele\htas-1, Cele\his-19, Cele\his-68, Cele\his-43, Cele\his-53, Cele\his-7, Cele\his-51, Cele\his-30, Cele\his-47, Cele\his-65, Cele\his-21, Cele\his-57" "Xtro\hist1h2aa, Xtro\hist1h2am, Xtro\h2afj, Xtro\hist1h2ah, Xtro\hist1h2ad, Xtro\h2afx, Xtro\hist1h2aj, Xtro\h2afy2, Xtro\h2afy" "Mmus\H2afx, Mmus\Hist1h2ah, Mmus\Hist1h2ai, Mmus\Hist2h2ac, Mmus\Hist1h2af, Mmus\Hist1h2ad, Mmus\Hist1h2ag, Mmus\H2afb1, Mmus\Hist1h2ak, Mmus\Hist1h2ao, Mmus\H2al1j, Mmus\Gm14920, Mmus\H2al2b, Mmus\Hist1h2an, Mmus\H2afj, Mmus\Hist2h2aa1, Mmus\H2afy2, Mmus\Hist1h2ab, Mmus\Hist2h2ab, Mmus\H2al2c, Mmus\H2al1n, Mmus\Hist1h2aa, Mmus\Hist3h2a, Mmus\Hist2h2aa2, Mmus\Hist1h2ap, Mmus\H2afy, Mmus\Hist2h3c1, Mmus\Hist1h2ae, Mmus\H2afb3, Mmus\Hist1h2ac, Mmus\H2afb2" "Hsap\H2AFB3, Hsap\H2AFJ, Hsap\HIST1H2AB, Hsap\H2AFY, Hsap\HIST2H2AB, Hsap\HIST1H2AI, Hsap\HIST2H2AA3, Hsap\HIST1H2AE, Hsap\HIST1H2AG, Hsap\HIST1H2AA, Hsap\H2AFB2, Hsap\HIST1H2AL, Hsap\HIST1H2AH, Hsap\HIST1H2AM, Hsap\HIST1H2AJ, Hsap\HIST2H2AC, Hsap\HIST1H2AK, Hsap\HIST3H2A, Hsap\HIST1H2AC, Hsap\H2AFB1, Hsap\HIST2H2AA4, Hsap\H2AFX, Hsap\HIST1H2AD, Hsap\H2AFY2" FBgn0035416 gry gryzun http://flybase.org/reports/FBgn0035416 protein_coding_gene - protein secretion ; GO:0009306 | inferred from mutant phenotype intracellular transport ; GO:0046907 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG17569, gry" "IPR021773:Foie gras liver health family 1, IPR025876:Trafficking protein particle complex subunit 11, C-terminal" CG17569 11-Aug-17 DroID_v2017_08 Drer\trappc11 - Cele\trpp-11 Xtro\trappc11 Mmus\Trappc11 Hsap\TRAPPC11 "memory defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0053817 His2A:CG33817 His2A:CG33817 http://flybase.org/reports/FBgn0053817 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33817, His2A:CG33817" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33817 11-Aug-17 DroID_v2017_08 "Drer\fbxl6, Drer\si:ch211-113a14.16, Drer\si:dkey-261m9.7, Drer\LOC100148591, Drer\si:ch211-113a14.7, Drer\si:dkey-108k21.15, Drer\si:ch211-113a14.19, Drer\si:dkey-261m9.15, Drer\zgc:110434, Drer\si:dkey-23a13.14, Drer\si:ch211-113a14.26, Drer\LOC100334934, Drer\zgc:173652, Drer\si:dkey-23a13.7, Drer\si:ch73-36p18.5, Drer\si:ch73-368j24.13, Drer\si:ch73-368j24.14, Drer\LOC570115, Drer\si:dkey-261m9.11, Drer\zgc:154164, Drer\zgc:101846, Drer\LOC100332229, Drer\si:dkey-108k21.26, Drer\si:ch211-113a14.11, Drer\zgc:114037, Drer\si:ch1073-159d7.10, Drer\si:dkey-108k21.19, Drer\si:dkey-261m9.18, Drer\si:ch1073-159d7.11, Drer\zgc:195633, Drer\h2afx, Drer\h2afy2, Drer\si:dkey-23a13.20" "Scer\HTA2, Scer\HTA1" "Cele\his-43, Cele\his-21, Cele\his-3, Cele\his-61, Cele\his-53, Cele\his-16, Cele\his-30, Cele\his-7, Cele\his-33, Cele\his-35, Cele\his-19, Cele\htas-1, Cele\his-47, Cele\his-65, Cele\his-12, Cele\his-51, Cele\his-68, Cele\his-57" "Xtro\hist1h2ad, Xtro\hist1h2am, Xtro\h2afy, Xtro\h2afy2, Xtro\hist1h2aa, Xtro\hist1h2aj, Xtro\h2afj, Xtro\hist1h2ah, Xtro\h2afx" "Mmus\H2afb1, Mmus\Hist1h2an, Mmus\H2al1j, Mmus\Gm14920, Mmus\Hist1h2ad, Mmus\H2afj, Mmus\H2al2b, Mmus\Hist1h2ac, Mmus\H2afb2, Mmus\H2afy2, Mmus\Hist1h2ah, Mmus\H2al2c, Mmus\Hist1h2ak, Mmus\H2afx, Mmus\Hist1h2ai, Mmus\Hist1h2ao, Mmus\Hist3h2a, Mmus\Hist2h2aa1, Mmus\H2afb3, Mmus\Hist2h3c1, Mmus\Hist1h2ag, Mmus\Hist2h2ab, Mmus\Hist2h2aa2, Mmus\Hist2h2ac, Mmus\H2afy, Mmus\Hist1h2ab, Mmus\H2al1n, Mmus\Hist1h2af, Mmus\Hist1h2ap, Mmus\Hist1h2ae, Mmus\Hist1h2aa" "Hsap\HIST1H2AK, Hsap\H2AFB3, Hsap\H2AFB1, Hsap\HIST2H2AA3, Hsap\HIST1H2AJ, Hsap\HIST1H2AI, Hsap\H2AFJ, Hsap\HIST1H2AA, Hsap\HIST1H2AC, Hsap\H2AFB2, Hsap\HIST1H2AG, Hsap\H2AFY2, Hsap\HIST2H2AC, Hsap\HIST2H2AA4, Hsap\HIST1H2AB, Hsap\HIST1H2AH, Hsap\HIST1H2AD, Hsap\HIST1H2AE, Hsap\HIST1H2AL, Hsap\HIST3H2A, Hsap\HIST2H2AB, Hsap\H2AFY, Hsap\H2AFX, Hsap\HIST1H2AM" FBgn0022800 Cad96Ca Cadherin 96Ca http://flybase.org/reports/FBgn0022800 FBgn0039289 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay inferred from mutant phenotype" "homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR020635 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity wound healing ; GO:0042060 | inferred from expression pattern Golgi organization ; GO:0007030 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of wound healing ; GO:0090303 | inferred from mutant phenotype" "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 apical part of cell ; GO:0045177 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity" "HD-14, DCad96Ca, CG10239, CG10244, CT28779, FGFR1-like, DmHD-14, Cad96Ca, Dm Cad96Ca, cad96Ca, stit, cad96C, Cad96C" "IPR000719:Protein kinase domain, IPR002126:Cadherin, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR015919:Cadherin-like, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG10244 11-Aug-17 DroID_v2017_08 "Drer\styk1, Drer\flt4, Drer\pdgfrb, Drer\fgfr2, Drer\kitb, Drer\csf1rb, Drer\fgfr3, Drer\flt3, Drer\LOC569566, Drer\tada2b, Drer\fgfr4, Drer\flt1, Drer\si:ch73-206d17.1, Drer\si:ch211-167j9.5, Drer\pdgfra, Drer\kita, Drer\fgfrl1b, Drer\fgfrl1a, Drer\ret, Drer\tek, Drer\tie1, Drer\fgfr1a, Drer\kdr, Drer\kdrl, Drer\si:dkey-14o18.6, Drer\pdgfrl, Drer\csf1ra" - "Cele\C24G6.2, Cele\egl-15, Cele\Y50D4B.6, Cele\kin-9, Cele\svh-2, Cele\R151.1, Cele\F09A5.2, Cele\kin-16, Cele\F09G2.1" "Xtro\pdgfra, Xtro\fgfr1, Xtro\fgfrl1, Xtro\styk1, Xtro\fgfr3, Xtro\flt4, Xtro\csf1r, Xtro\fgfr2, Xtro\pdgfrl, Xtro\tie1, Xtro\pdgfrl.2, Xtro\flt1, Xtro\fgfr4, Xtro\ret, Xtro\kdr, Xtro\tek, Xtro\tada2b" "Mmus\Tek, Mmus\Csf1r, Mmus\Flt1, Mmus\Kdr, Mmus\Fgfrl1, Mmus\Fgfr2, Mmus\Fgfr3, Mmus\Tie1, Mmus\Pdgfra, Mmus\Kit, Mmus\Ret, Mmus\Pdgfrl, Mmus\Fgfr4, Mmus\Styk1, Mmus\Tada2b, Mmus\Fgfr1, Mmus\Flt3, Mmus\Pdgfrb, Mmus\Flt4" "Hsap\FLT4, Hsap\PDGFRA, Hsap\ARAF, Hsap\FGFR1, Hsap\FGFR2, Hsap\FGFR3, Hsap\FLT1, Hsap\RET, Hsap\TIE1, Hsap\FGFR4, Hsap\KDR, Hsap\TADA2B, Hsap\TEK, Hsap\FGFRL1, Hsap\PDGFRB, Hsap\CSF1R, Hsap\PDGFRL, Hsap\STYK1, Hsap\FLT3, Hsap\KIT" "lethal - all die during pupal stage,lethal - all die during embryonic stage,wound healing defective,lethal - all die before end of pupal stage,some die during pupal stage,viable" DRSC16693 K -0.161515465 -0.354177669 0.754090978 0.232806314 0.027884024 -1.517751387 FBgn0036538 CG15715 - http://flybase.org/reports/FBgn0036538 protein_coding_gene - - - "BcDNA:RE26825, CG15715" "IPR026939:At2g23090-like, IPR007513:Uncharacterised protein family SERF" CG15715 11-Aug-17 DroID_v2017_08 "Drer\znf706, Drer\zgc:91910" - "Cele\C01F6.9, Cele\K10B3.1" "Xtro\znf706, Xtro\znf706.2" Mmus\Zfp706 Hsap\ZNF706 "viable,fertile" DRSC25332 K 0.351683277 0.353118799 -0.166410811 0.315967154 -1.708995587 0.556850082 FBgn0001138 grn grain http://flybase.org/reports/FBgn0001138 "FBgn0004213, FBgn0015228, FBgn0019991" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with pnr chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001228 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 RNA polymerase II transcription factor binding ; GO:0001085 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088 positive regulation of T cell differentiation ; GO:0045582 | inferred from electronic annotation with InterPro:IPR029521 tissue development ; GO:0009888 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype animal organ morphogenesis ; GO:0009887 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000801139 "GRAIN, dGatac, dGATAc, Gata-c, GATAc, dGATA-2, gra, l(3)84Fa, Gata2, CG9656, grn, CG9656-PA, Grn" "IPR000679:Zinc finger, GATA-type, IPR013088:Zinc finger, NHR/GATA-type, IPR029521:Transcription factor GATA-3" CG9656 11-Aug-17 DroID_v2017_08 "Drer\gata5, Drer\gata6, Drer\gata2a, Drer\gata3, Drer\gata2b, Drer\gata1b, Drer\gata4, Drer\zglp1, Drer\gata1a, Drer\trps1" "Scer\GAT1, Scer\GZF3, Scer\SRD1, Scer\GAT2, Scer\ECM23, Scer\GLN3, Scer\DAL80, Scer\GAT3, Scer\GAT4" "Cele\elt-1, Cele\end-3, Cele\med-2, Cele\end-1, Cele\elt-4, Cele\elt-3, Cele\nhr-239, Cele\elt-6, Cele\med-1, Cele\elt-7, Cele\elt-2, Cele\egl-18" "Xtro\gata2, Xtro\gata4, Xtro\gata1, Xtro\gata5, Xtro\gata6, Xtro\gata3, Xtro\trps1" "Mmus\Gata5, Mmus\Gata6, Mmus\Gata4, Mmus\Gata3, Mmus\Zglp1, Mmus\Gata2, Mmus\Trps1, Mmus\Gata1" "Hsap\GATA5, Hsap\TRPS1, Hsap\ZGLP1, Hsap\GATA1, Hsap\GATA6, Hsap\GATA3, Hsap\GATA2, Hsap\GATA4" " embryonic stage | stage >=12 , embryonic stage | stage >=5 , embryonic stage | stage >=11 , embryonic stage | stage 5 , embryonic stage | cellular blastoderm | late " " embryonic brain

, embryonic central nervous system

segmentally repeated , optic lobe

, organism

, embryonic central nervous system

, anterior midgut proper primordium

, organism | ventral

, labral segment

anterior , embryonic head | precursor & dorsal

, organism | 40-60% egg length & dorsal

,

15-25% egg length <&> dorsal , posterior midgut proper primordium

, embryonic/larval posterior spiracle

" "lethal,recessive,visible,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective" "cephalopharyngeal skeleton,filzkorper,leg,proximal,somatic clone,tibia,femur,stigmatophore,intersegmental nerve,lateral process,dorsal bridge,aCC neuron,RP2 motor neuron,denticle belt,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic telson" DRSC16961 E 0.207795218 0.896968844 1.541151876 -0.512022324 -1.496466098 0.13437874 FBgn0031114 cactin cactin http://flybase.org/reports/FBgn0031114 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:29938 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q03017 "dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype inferred from genetic interaction with cact neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG1676, cactin, Cactin" "IPR018816:Cactin, central domain, IPR019134:Cactin, C-terminal" CG1676 11-Aug-17 DroID_v2017_08 "Drer\LOC103908635, Drer\cactin, Drer\marveld3, Drer\si:ch211-191a24.4" - Cele\cacn-1 Xtro\cactin "Mmus\Marveld3, Mmus\Cactin" "Hsap\MARVELD3, Hsap\CACTIN" "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC20576 I 0.369370613 1.935209779 0.261236265 0.572818458 -0.63956845 -0.437344408 FBgn0033966 CG12856 - http://flybase.org/reports/FBgn0033966 protein_coding_gene - - - "CT31996, CG12856" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC23818 K -0.617822516 -0.359490066 -0.033416717 0.191489721 -1.667674287 -0.631814433 FBgn0028867 CR15280 - http://flybase.org/reports/FBgn0028867 pseudogene_attribute - - - "CR15280, SPH204, BG:DS06874.4, CG15280" - CR15280 11-Aug-17 DroID_v2017_08 - - - - - - DRSC01953 I 0.680895165 1.583823029 1.388842966 0.196500047 -1.28410413 -0.551679286 FBgn0034878 pita pita http://flybase.org/reports/FBgn0034878 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 protein binding ; GO:0005515 | inferred from physical interaction with Cp190 chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay "DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay" polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG3941, spdk, pita, Pita, PITA" "IPR013087:Zinc finger C2H2-type, IPR012934:Zinc finger, AD-type" CG3941 11-Aug-17 DroID_v2017_08 "Drer\LOC100534979, Drer\si: zfos-932h1.3, Drer\si:dkeyp-121d2.7, Drer\znf1174" Scer\AZF1 "Cele\ces-1, Cele\zfp-2, Cele\Y55F3AM.14, Cele\hinf-1" - Mmus\Rbak Hsap\ZNF121 "lethal,recessive,mitotic cell cycle defective,germline clone,maternal effect,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,female semi-sterile,lethal - all die before end of prepupal stage,some die during prepupal stage,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval digestive system,melanotic mass,mitotic metaphasebw5),condensed nuclear chromosomebw5),spindlebw5),mitotic anaphasebw5),egg chamber,germline clone,follicle cell,nurse cell & nucleus | germ-line clone,nurse cell,nurse cell & polytene chromosome | germ-line clone,mitotic metaphase,condensed nuclear chromosome,spindle,mitotic anaphase,mitotic G2 phase,embryonic/larval salivary gland,imaginal disc,embryonic/larval tracheal system" DRSC04435 EK 0.049888981 -0.897190165 -0.84732436 -3.633452113 0.470685556 1.942202897 FBgn0015296 Shc SHC-adaptor protein http://flybase.org/reports/FBgn0015296 FBgn0035990 protein_coding_gene receptor tyrosine kinase binding ; GO:0030971 | inferred from biological aspect of ancestor with PANTHER:PTN000818658 "tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor TORC1 signaling ; GO:0038202 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with Egfr" plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000818658 "dshc, shc, DSHC, D-Shc, dShc, CG3715, Shc" "IPR000980:SH2 domain, IPR006019:Phosphotyrosine interaction domain, Shc-like, IPR006020:PTB/PI domain, IPR011993:PH domain-like" CG3715 11-Aug-17 DroID_v2017_08 "Drer\shc3, Drer\shc2, Drer\shc1" - "Cele\C25A8.5, Cele\shc-1" "Xtro\shc2, Xtro\shc4, Xtro\shc3, Xtro\shf" "Mmus\Shc4, Mmus\Shc2, Mmus\Shc1, Mmus\Shc3" "Hsap\SHC2, Hsap\SHC4, Hsap\SHC3, Hsap\GULP1, Hsap\SHC1, Hsap\SHD" "partially lethal - majority die,recessive,female sterile,lethal,maternal effect,planar polarity defective,male sterile,visible,germline clone,terminal phenotype,viable,immune response defective" "mesoderm,germline clone,embryonic/first instar larval cuticle,maternal effect,denticle belt,filzkorper,embryonic abdominal segment 8,Malpighian tubule,cephalopharyngeal skeleton,extended germ band embryo,egg,eye,wing,ovary,ommatidium,anterior,eye photoreceptor cell,wing vein L4,distal,dorsal appendage,chorion | maternal effect,dorsal air sac primordium,somatic clone,border follicle cell,embryo" DRSC11284 IE -0.269129314 -1.608022249 -1.609210849 -0.254884096 -1.13792851 -1.484316015 FBgn0050010 CG30010 - http://flybase.org/reports/FBgn0050010 protein_coding_gene molecular_function ; GO:0003674 | no biological data available wound healing ; GO:0042060 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "BcDNA:SD18306, CG30010" IPR028108:Protein of unknown function DUF4505 CG30010 11-Aug-17 DroID_v2017_08 Drer\si:ch1073-287p18.1 - Cele\F59C6.12 - Mmus\C030006K11Rik Hsap\C8orf82 viable FBgn0037084 Syx6 Syntaxin 6 http://flybase.org/reports/FBgn0037084 protein_coding_gene SNAP receptor activity ; GO:0005484 | non-traceable author statement SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNAP receptor activity ; GO:0005484 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 Golgi vesicle transport ; GO:0048193 | inferred from electronic annotation with InterPro:IPR015260 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 vesicle-mediated transport ; GO:0016192 | non-traceable author statement vesicle docking ; GO:0048278 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 SNARE complex ; GO:0031201 | colocalizes_with inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000461349 plasma membrane ; GO:0005886 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "CG7736, CT23545, DmSyx6, Dm Syx6, SYX6/10, Syx6, Syx, SYN6" "IPR000727:Target SNARE coiled-coil homology domain, IPR010989:SNARE, IPR015260:Syntaxin 6, N-terminal" CG7736 11-Aug-17 DroID_v2017_08 "Drer\stx8, Drer\stx6, Drer\stx10" "Scer\VAM7, Scer\SYN8, Scer\TLG1" Cele\syx-6 "Xtro\stx10, Xtro\stx6, Xtro\stx8" "Mmus\Stx8, Mmus\Stx6" "Hsap\STX6, Hsap\STX8, Hsap\STX10" "viable,fertile" FBgn0053844 His2A:CG33844 His2A:CG33844 http://flybase.org/reports/FBgn0053844 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33844, His2A:CG33844" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33844 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-113a14.7, Drer\si:dkey-261m9.7, Drer\si:dkey-261m9.11, Drer\si:ch73-368j24.13, Drer\si:ch73-368j24.14, Drer\si:dkey-108k21.15, Drer\fbxl6, Drer\si:ch211-113a14.26, Drer\si:dkey-261m9.18, Drer\LOC100148591, Drer\si:ch211-113a14.11, Drer\zgc:195633, Drer\LOC570115, Drer\si:ch211-113a14.16, Drer\zgc:173652, Drer\si:dkey-108k21.19, Drer\si:dkey-108k21.26, Drer\si:ch1073-159d7.11, Drer\si:dkey-23a13.7, Drer\si:dkey-23a13.14, Drer\LOC100334934, Drer\h2afy2, Drer\si:dkey-23a13.20, Drer\si:dkey-261m9.15, Drer\zgc:154164, Drer\zgc:101846, Drer\si:ch211-113a14.19, Drer\si:ch1073-159d7.10, Drer\si:ch73-36p18.5, Drer\zgc:114037, Drer\h2afx, Drer\LOC100332229, Drer\zgc:110434" "Scer\HTA1, Scer\HTA2" "Cele\his-61, Cele\his-33, Cele\his-47, Cele\his-68, Cele\his-51, Cele\his-53, Cele\his-12, Cele\his-21, Cele\his-43, Cele\his-57, Cele\his-7, Cele\his-3, Cele\his-30, Cele\his-35, Cele\his-19, Cele\his-65, Cele\his-16, Cele\htas-1" "Xtro\h2afy, Xtro\hist1h2ah, Xtro\hist1h2am, Xtro\hist1h2aj, Xtro\hist1h2ad, Xtro\h2afj, Xtro\h2afy2, Xtro\hist1h2aa, Xtro\h2afx" "Mmus\Hist1h2ao, Mmus\Hist1h2ad, Mmus\H2al2c, Mmus\H2afy2, Mmus\Hist2h2ac, Mmus\Hist1h2ah, Mmus\Hist1h2ag, Mmus\H2al1n, Mmus\Hist1h2af, Mmus\Hist1h2ae, Mmus\Hist1h2aa, Mmus\Hist2h2ab, Mmus\H2afb1, Mmus\H2al1j, Mmus\Hist3h2a, Mmus\Hist2h3c1, Mmus\H2afy, Mmus\Hist1h2ac, Mmus\H2afj, Mmus\H2afb2, Mmus\Hist1h2ab, Mmus\H2afb3, Mmus\H2afx, Mmus\Hist1h2ak, Mmus\Hist1h2ap, Mmus\Gm14920, Mmus\Hist1h2ai, Mmus\Hist1h2an, Mmus\H2al2b, Mmus\Hist2h2aa2, Mmus\Hist2h2aa1" "Hsap\H2AFY, Hsap\HIST1H2AD, Hsap\HIST1H2AC, Hsap\HIST1H2AK, Hsap\HIST1H2AE, Hsap\H2AFX, Hsap\HIST1H2AG, Hsap\HIST1H2AB, Hsap\HIST2H2AB, Hsap\HIST1H2AA, Hsap\HIST2H2AA4, Hsap\HIST1H2AL, Hsap\HIST1H2AM, Hsap\HIST3H2A, Hsap\H2AFJ, Hsap\H2AFB1, Hsap\HIST1H2AJ, Hsap\HIST1H2AI, Hsap\HIST1H2AH, Hsap\HIST2H2AA3, Hsap\HIST2H2AC, Hsap\H2AFB3, Hsap\H2AFB2, Hsap\H2AFY2" FBgn0032005 Snx6 Sorting nexin 6 http://flybase.org/reports/FBgn0032005 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from sequence or structural similarity with SGD:S000005658 protein transporter activity ; GO:0008565 | contributes_to inferred from sequence or structural similarity with SGD:S000005658 "positive regulation of Wnt protein secretion ; GO:0061357 | inferred from mutant phenotype NOT retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with SGD:S000005658 vesicle organization ; GO:0016050 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 endocytosis ; GO:0006897 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 canonical Wnt signaling pathway ; GO:0060070 | NOT inferred from mutant phenotype" "extrinsic component of membrane ; GO:0019898 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000058569 endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000005658 retromer, tubulation complex ; GO:0030905 | inferred from sequence or structural similarity with SGD:S000005658" "Dsnx6, CG8282, Snx6, DmSNX6, SNX6" "IPR001683:Phox homologous domain, IPR014637:Sorting nexin-5/6/32, IPR015404:Sorting nexin Vps5-like, C-terminal" CG8282 11-Aug-17 DroID_v2017_08 "Drer\snx5, Drer\snx6" "Scer\SNX3, Scer\ATG20, Scer\VPS5, Scer\SNX4, Scer\SNX41, Scer\VPS17, Scer\YKR078W" "Cele\snx-6, Cele\snx-3" "Xtro\snx6, Xtro\snx5" "Mmus\Snx32, Mmus\Snx6, Mmus\Snx5" "Hsap\SNX32, Hsap\SNX5, Hsap\SNX6" "viable,fertile" FBgn0085370 Pde11 Phosphodiesterase 11 http://flybase.org/reports/FBgn0085370 protein_coding_gene "3',5'-cyclic-AMP phosphodiesterase activity ; GO:0004115 | inferred from direct assay 3',5'-cyclic-GMP phosphodiesterase activity ; GO:0047555 | inferred from direct assay" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002073 cAMP metabolic process ; GO:0046058 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype cGMP metabolic process ; GO:0046068 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG34341, PDE11, CG10231, Pde11, CG15159" "IPR003607:HD/PDEase domain, IPR002073:3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR003018:GAF domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029016:GAF domain-like, IPR023088:3'5'-cyclic nucleotide phosphodiesterase, IPR023174:3'5'-cyclic nucleotide phosphodiesterase, conserved site" CG34341 11-Aug-17 DroID_v2017_08 "Drer\pde4d, Drer\pde10a, Drer\pde4bb, Drer\pde4ca, Drer\pde6b, Drer\pde9al, Drer\pde6a, Drer\pde2a, Drer\pde11al, Drer\pde6c, Drer\pde5aa, Drer\si:dkey-219c10.4, Drer\pde5ab, Drer\crtc1b, Drer\pde11a, Drer\pde4ba, Drer\pde9a, Drer\LOC571737, Drer\pde7a, Drer\pde4a" Scer\PDE2 Cele\pde-5 "Xtro\pde7a, Xtro\pde4b, Xtro\pde4d, Xtro\pde4c, Xtro\pde7b, Xtro\pde6b, Xtro\pde6c, Xtro\pde6a, Xtro\pde9a, Xtro\pde10a, Xtro\pde5a, Xtro\pde2a, Xtro\pde11a, Xtro\LOC100493061, Xtro\pde4a" "Mmus\Pde5a, Mmus\Pde6c, Mmus\Pde9a, Mmus\Pde6b, Mmus\Pde4b, Mmus\Pde2a, Mmus\Pde4d, Mmus\Pde6a, Mmus\Pde4c, Mmus\Pde7a, Mmus\Pde10a, Mmus\Pde7b, Mmus\Pde11a, Mmus\Pde4a" "Hsap\PDE11A, Hsap\PDE7B, Hsap\PDE5A, Hsap\PDE2A, Hsap\PDE6C, Hsap\PDE4D, Hsap\PDE4A, Hsap\PDE9A, Hsap\PDE6A, Hsap\PDE4B, Hsap\PDE4C, Hsap\PDE6B, Hsap\PDE10A, Hsap\PDE7A" DRSC02460 I 1.540155241 2.585501496 0.480045917 0.778721416 0.056043881 1.452449857 FBgn0053833 His3:CG33833 His3:CG33833 http://flybase.org/reports/FBgn0053833 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33833, His3:CG33833" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33833 11-Aug-17 DroID_v2017_08 "Drer\cenpa, Drer\si:ch1073-429i10.3, Drer\si:ch73-36p18.2, Drer\zgc:113984, Drer\hist2h3c, Drer\zgc:113983, Drer\h3f3c, Drer\zgc:173552, Drer\LOC108190747, Drer\LOC108190746, Drer\hist2h3ca1, Drer\h3f3b.1, Drer\h3f3d, Drer\h3f3a" "Scer\CSE4, Scer\HHT1, Scer\HHT2" "Cele\his-6, Cele\his-2, Cele\his-27, Cele\his-63, Cele\his-49, Cele\his-25, Cele\his-59, Cele\his-9, Cele\his-17, Cele\his-13, Cele\his-69, Cele\his-32, Cele\his-55, Cele\his-74, Cele\his-42, Cele\his-71, Cele\his-45, Cele\his-72" "Xtro\hist2h3d, Xtro\h3f3b, Xtro\LOC100495788, Xtro\cenpa" "Mmus\Hist1h3e, Mmus\H3f3a, Mmus\Hist1h3a, Mmus\Hist2h3c1, Mmus\Hist2h3b, Mmus\Hist1h3c, Mmus\Hist1h3h, Mmus\Hist1h3g, Mmus\Hist1h3i, Mmus\Hist1h3f, Mmus\Cenpa, Mmus\Hist1h3d, Mmus\Hist1h3b, Mmus\H3f3b, Mmus\Hist2h3c2" "Hsap\HIST3H3, Hsap\H3F3C, Hsap\HIST1H3D, Hsap\HIST1H3E, Hsap\CENPA, Hsap\HIST1H3H, Hsap\HIST1H3A, Hsap\HIST2H3C, Hsap\HIST1H3J, Hsap\HIST1H3G, Hsap\H3F3A, Hsap\HIST2H3A, Hsap\HIST1H3I, Hsap\HIST1H3B, Hsap\HIST2H3D, Hsap\HIST1H3C, Hsap\HIST1H3F, Hsap\H3F3B" FBgn0266709 Zmynd10 Zinc finger MYND-type containing 10 http://flybase.org/reports/FBgn0266709 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype motile cilium assembly ; GO:0044458 | inferred from mutant phenotype axoneme assembly ; GO:0035082 | inferred from mutant phenotype proprioception ; GO:0019230 | inferred from mutant phenotype outer dynein arm assembly ; GO:0036158 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype neuronal cell body ; GO:0043025 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay inferred from mutant phenotype "CG11253, Zmynd10" "IPR002893:Zinc finger, MYND-type, IPR017333:Uncharacterised conserved protein UCP037948, zinc finger MYND-type" CG11253 11-Aug-17 DroID_v2017_08 Drer\zmynd10 - - Xtro\zmynd10 Mmus\Zmynd10 Hsap\ZMYND10 FBgn0032042 CG13398 - http://flybase.org/reports/FBgn0032042 protein_coding_gene insulin receptor binding ; GO:0005158 | inferred from electronic annotation with InterPro:IPR002404 - - CG13398 "IPR002404:IRS-type PTB domain, IPR011993:PH domain-like" CG13398 11-Aug-17 DroID_v2017_08 "Drer\dok4, Drer\dok3, Drer\dok6, Drer\frs2a, Drer\dok1b, Drer\dok1a, Drer\dok2, Drer\frs3, Drer\frs2b" - Cele\rog-1 "Xtro\dok2, Xtro\frs3, Xtro\dok5, Xtro\dok1, Xtro\frs2, Xtro\dok4" "Mmus\Dok6, Mmus\Frs2, Mmus\Dok1, Mmus\Dok3, Mmus\Frs3, Mmus\Dok2, Mmus\Dok4, Mmus\Dok5" "Hsap\FRS3, Hsap\DOK6, Hsap\FRS2, Hsap\DOK3, Hsap\DOK4, Hsap\DOK1, Hsap\DOK2, Hsap\DOK5" "viable,visible" trichogen cell FBgn0037010 CG4825 - http://flybase.org/reports/FBgn0037010 protein_coding_gene - phosphatidylserine biosynthetic process ; GO:0006659 | inferred from electronic annotation with InterPro:IPR004277 neurogenesis ; GO:0022008 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay "CG4825, ptdss1" IPR004277:Phosphatidyl serine synthase CG4825 11-Aug-17 DroID_v2017_08 "Drer\ptdss1a, Drer\ptdss2, Drer\ptdss1b" - "Cele\pssy-2, Cele\pssy-1" Xtro\ptdss1 "Mmus\Ptdss2, Mmus\Ptdss1" "Hsap\PTDSS1, Hsap\PTDSS2" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0083953 CG34117 - http://flybase.org/reports/FBgn0083953 protein_coding_gene - - - CG34117 - CG34117 11-Aug-17 DroID_v2017_08 Drer\si:ch1073-314i13.4 - Cele\C29E4.12 Xtro\c7orf55 Mmus\Fmc1 "Hsap\LUC7L2, Hsap\FMC1" FBgn0004103 Pp1-87B Protein phosphatase 1 at 87B http://flybase.org/reports/FBgn0004103 "FBgn0002338, FBgn0003133, FBgn0003597, FBgn0010090, FBgn0011795, FBgn0038044" protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from mutant phenotype protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement myosin phosphatase activity ; GO:0017018 | inferred from direct assay protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity "positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from genetic interaction with flw, Pp1α-96A visual learning ; GO:0008542 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement olfactory learning ; GO:0008355 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype beta-catenin destruction complex disassembly ; GO:1904886 | inferred from sequence or structural similarity with UniProtKB:P62139 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype learning or memory ; GO:0007611 | non-traceable author statement locomotion ; GO:0040011 | non-traceable author statement adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity spindle assembly ; GO:0051225 | inferred from mutant phenotype" protein phosphatase type 1 complex ; GO:0000164 | colocalizes_with inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay protein phosphatase type 1 complex ; GO:0000164 | inferred from sequence or structural similarity "PP1, DmPp1-87B, PP1alpha87B, Su(var)3-6, PP1-87B, PP1c, PP187B, CG5650, PP1 87B, Pp1-87Bb, Su-var(3)6, Su(Var)3-6, l(3)j6E7, Pp1, Suvar(3)6, su-var(3)6, ck19, Su(var)(3)6, PP1A87B, PP1alpha[[2]], PP-1alpha, l(3)ck19, l(3)87Bg, Pp-1alpha, Pp1-87B, PP1alpha-87B, Ppl-87B, 87B, pp1-87B, PP1c 87B, Pp1alpha-87B, PP1 beta87b, dPP1beta, PP1B, PPI 87B" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like, IPR031675:Serine-threonine protein phosphatase, N-terminal" CG5650 11-Aug-17 DroID_v2017_08 "Drer\ppp1cab, Drer\ppp1cc, Drer\ppp1cb, Drer\ppp1caa" "Scer\PPZ1, Scer\PPQ1, Scer\PPZ2, Scer\GLC7" "Cele\pph-1, Cele\F52H3.6, Cele\gsp-2, Cele\ZK938.1, Cele\F20D6.6, Cele\gsp-4, Cele\gsp-1" "Xtro\ppp1ca, Xtro\ppp1cc, Xtro\ppp1cb" "Mmus\Ppp1cb, Mmus\Gm5601, Mmus\Ppp1cc, Mmus\Ppp1ca" "Hsap\PPP1CC, Hsap\PPP1CA, Hsap\PPP1CB" embryonic stage -- adult stage "lethal,recessive,wild-type,partially lethal - majority die,mitotic cell cycle defective,suppressor of variegation,dominant,visible,somatic clone,non-suppressor of variegation" "nuclear chromosome,photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,embryonic/larval optic neuropil,neuroblast,ganglion mother cell,mitosis & nuclear chromosome,imaginal disc,eye photoreceptor cell,somatic clone,eye,eye disc,photoreceptor cell R1 & axonGMR.PF,photoreceptor cell R2 & axonGMR.PF,photoreceptor cell R3 & axonGMR.PF,photoreceptor cell R4 & axonGMR.PF,photoreceptor cell R5 & axonGMR.PF" DRSC27290 IEK 0.336188476 -4.196731104 3.176679563 -5.573582866 -1.344984059 -1.902052782 FBgn0037240 Cont Contactin http://flybase.org/reports/FBgn0037240 protein_coding_gene - cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype nerve maturation ; GO:0021682 | inferred from mutant phenotype axon ensheathment ; GO:0008366 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred by curator from GO:0005918 septate junction assembly ; GO:0019991 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype septate junction ; GO:0005918 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "Cont, cont, DCONT, D-Axonin, CG1084, CT1481, CONT" "IPR001304:C-type lectin-like, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold, IPR013151:Immunoglobulin" CG1084 11-Aug-17 DroID_v2017_08 "Drer\nfascb, Drer\cntn3b, Drer\cntn3a.2, Drer\cntn4, Drer\nfasca, Drer\nadl1.2, Drer\cntn5, Drer\nrcamb, Drer\cntn2, Drer\cntn3a.1, Drer\cntn1a, Drer\cntn1b, Drer\LOC101883325, Drer\nadl1.1, Drer\nrcama" - "Cele\igcm-1, Cele\lad-2, Cele\rig-6" "Xtro\cntn5, Xtro\cntn1, Xtro\nfasc, Xtro\l1cam, Xtro\cntn2, Xtro\nrcam" "Mmus\Chl1, Mmus\Nfasc, Mmus\Cntn5, Mmus\Cntn1, Mmus\Cntn4, Mmus\Cntn3, Mmus\Nrcam, Mmus\Cntn2, Mmus\Cntn6, Mmus\L1cam" "Hsap\NFASC, Hsap\CNTN5, Hsap\CNTN4, Hsap\L1CAM, Hsap\CNTN1, Hsap\CNTN3, Hsap\NRCAM, Hsap\CHL1, Hsap\CNTN2, Hsap\CNTN6" "lethal,viable,visible" "embryonic epidermis & pleated septate junction,salivary gland,abdominal lateral pentascolopidial chordotonal organ lch5,scolopidium & abdominal lateral pentascolopidial chordotonal organ lch5,septate junction & peripheral glial cell,axolemma & nerve,trichogen cell" FBgn0001091 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1 http://flybase.org/reports/FBgn0001091 FBgn0043822 protein_coding_gene NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR006424 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006424 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ; GO:0004365 | inferred from direct assay "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006424, InterPro:IPR020828, InterPro:IPR020829, InterPro:IPR020830, InterPro:IPR020831 glucose metabolic process ; GO:0006006 | inferred from electronic annotation with InterPro:IPR006424 somatic muscle development ; GO:0007525 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype glycolytic process ; GO:0006096 | inferred from expression pattern" M band ; GO:0031430 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Gapdh1, Gapdh, GAPDH I, CG12055, GADPH, GAPDH-1, gapdh-1, Gapdh-1, GAPDH, Gapd, GA3PDH, gh12586, BEST:GH12586, Gapdh43E, gapdh, GAP, GAPDHI, GAPDH1, gapdh1" "IPR006424:Glyceraldehyde-3-phosphate dehydrogenase, type I, IPR020828:Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain, IPR020829:Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, IPR020830:Glyceraldehyde 3-phosphate dehydrogenase, active site, IPR020831:Glyceraldehyde/Erythrose phosphate dehydrogenase family, IPR016040:NAD(P)-binding domain" CG12055 11-Aug-17 DroID_v2017_08 "Drer\gapdh, Drer\gapdhs" "Scer\TDH1, Scer\TDH3, Scer\TDH2" "Cele\gpd-1, Cele\gpd-3, Cele\gpd-2, Cele\gpd-4" Xtro\gapdh "Mmus\Gapdh-ps15, Mmus\Gapdh, Mmus\Gapdhs, Mmus\Pnmal2" "Hsap\GAPDH, Hsap\PNMAL2, Hsap\GAPDHS" adult stage viable "embryonic/larval somatic muscle,embryonic myoblast" FBgn0034231 APC10 Anaphase Promoting Complex subunit 10 http://flybase.org/reports/FBgn0034231 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from sequence or structural similarity with SGD:S000003209 regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from electronic annotation with InterPro:IPR016901 protein K11-linked ubiquitination ; GO:0070979 | inferred from biological aspect of ancestor with PANTHER:PTN000309720 neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype endomitotic cell cycle ; GO:0007113 | inferred from genetic interaction with Cdc23 anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from biological aspect of ancestor with PANTHER:PTN000309720 anaphase-promoting complex ; GO:0005680 | inferred from biological aspect of ancestor with PANTHER:PTN000309720 "APC10, CG11419, Apc10" "IPR004939:APC10/DOC domain, IPR008979:Galactose-binding domain-like, IPR016901:Anaphase-promoting complex subunit 10" CG11419 11-Aug-17 DroID_v2017_08 Drer\anapc10 Scer\DOC1 "Cele\Y48G1C.12, Cele\apc-10" Xtro\anapc10 Mmus\Anapc10 Hsap\ANAPC10 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0263933 ebi ebi http://flybase.org/reports/FBgn0263933 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay RNA polymerase II transcription corepressor activity ; GO:0001106 | contributes_to inferred from physical interaction with sna GTP binding ; GO:0005525 | inferred from sequence or structural similarity repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with sna protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q27934 protein binding ; GO:0005515 | inferred from physical interaction with HDAC3 protein binding ; GO:0005515 | inferred from physical interaction with Smyd4-2 "positive regulation of Notch signaling pathway ; GO:0045747 | inferred from direct assay inferred from genetic interaction with N wing disc development ; GO:0035220 | inferred from mutant phenotype inferred from genetic interaction with sd inferred from genetic interaction with vg inferred from genetic interaction with N cellular response to light stimulus ; GO:0071482 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with Jra inferred from genetic interaction with hep inferred from genetic interaction with egr inferred from genetic interaction with puc positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype inferred from genetic interaction with aos inferred from genetic interaction with Pi3K92E neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype compound eye cone cell fate commitment ; GO:0042676 | traceable author statement proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype photoreceptor cell development ; GO:0042461 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | traceable author statement negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype positive regulation of histone deacetylation ; GO:0031065 | inferred from direct assay response to oxidative stress ; GO:0006979 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | traceable author statement" transcriptional repressor complex ; GO:0017053 | inferred from genetic interaction with Su(H) inferred from physical interaction with Smr nucleus ; GO:0005634 | inferred from direct assay histone deacetylase complex ; GO:0000118 | inferred from biological aspect of ancestor with PANTHER:PTN000521099 polytene chromosome ; GO:0005700 | inferred from direct assay "ebi, Ebi, CG4063, FBXW4, Tbl1, Tb11, l(2)k16213, E-2f, E-2g" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR006594:LIS1 homology motif, IPR020472:G-protein beta WD-40 repeat, IPR019775:WD40 repeat, conserved site, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily" CG4063 11-Aug-17 DroID_v2017_08 "Drer\tbl1x, Drer\tbl1xr1a, Drer\tbl1xr1b" Scer\SIF2 Cele\unc-37 "Xtro\tbl1xr1, Xtro\tbl1x" "Mmus\Tbl1xr1, Mmus\Wdr17, Mmus\Tbl1x" "Hsap\TBL1Y, Hsap\WDR38, Hsap\TBL1X, Hsap\TBL1XR1" FBgn0034973 CG13564 - http://flybase.org/reports/FBgn0034973 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to bacterium ; GO:0042742 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000480690 "CG13564, Minos1c" IPR007512:Protein of unknown function DUF543 CG13564 11-Aug-17 DroID_v2017_08 Drer\minos1 Scer\MIC10 Cele\F54A3.5 - Mmus\Minos1 "Hsap\MINOS1, Hsap\MINOS1-NBL1" viable DRSC04201 K 0.780892919 -0.090161326 1.215596426 0.402170069 -0.270571265 1.717710358 FBgn0010750 atms antimeros http://flybase.org/reports/FBgn0010750 "FBgn0011800, FBgn0037274, FBgn0046477, FBgn0046478, FBgn0046479" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VRP5 "histone modification ; GO:0016570 | inferred from electronic annotation with InterPro:IPR007133 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from electronic annotation with InterPro:IPR007133 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" transcriptionally active chromatin ; GO:0035327 | inferred from direct assay Cdc73/Paf1 complex ; GO:0016593 | inferred from direct assay "l(3)01456, l(3)02466, CG2503, l(3)rK509, anon-WO0172774.116, anon-WO0172774.114, anon-WO0172774.113, atms, Paf1, PAF, PAF1, Atms" IPR007133:RNA polymerase II associated factor Paf1 CG2503 11-Aug-17 DroID_v2017_08 "Drer\bbs5, Drer\klhl40b, Drer\paf1, Drer\klhl41b, Drer\klhl40a, Drer\klhl41a" Scer\PAF1 "Cele\pafo-1, Cele\bbs-5, Cele\tag-343" "Xtro\paf1, Xtro\klhl41, Xtro\klhl40, Xtro\bbs5" "Mmus\Klhl40, Mmus\Paf1, Mmus\Klhl41, Mmus\Bbs5" "Hsap\BBS5, Hsap\PAF1, Hsap\KLHL40" "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC27502 EK -1.004259984 1.265092852 3.040033215 -0.268666225 1.357426518 3.362819086 FBgn0030889 CG15373 - http://flybase.org/reports/FBgn0030889 protein_coding_gene - - - CG15373 "IPR022110:Casc1 domain, IPR031826:Cancer susceptibility candidate 1, N-terminal" CG15373 11-Aug-17 DroID_v2017_08 Drer\casc1 - Cele\K09E2.2 - Mmus\Casc1 Hsap\CASC1 viable DRSC19663 K -0.431712065 -0.251687335 0.181151162 -0.103639173 1.617624776 0.856345188 FBgn0010423 TpnC47D Troponin C at 47D http://flybase.org/reports/FBgn0010423 FBgn0064889 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - "TnC, DmTpnCIb, DmTpnC47D, TpnC Ib, TNC, DmTnC2, CG9073, TnC47D, BcDNA:RE34610, TpnC47D, TpnCIb, TNC47D, Tnc3" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG9073 11-Aug-17 DroID_v2017_08 "Drer\efcab6, Drer\efcab11, Drer\calm1a, Drer\calml4a, Drer\cabp1b, Drer\cabp4, Drer\tnnc2, Drer\pvalb6, Drer\pvalb4, Drer\pvalb1, Drer\tnnc1a, Drer\calb2a, Drer\cabp5b, Drer\pvalb8, Drer\pvalb3, Drer\cabp5a, Drer\calm3a, Drer\scgn, Drer\calb1, Drer\calm1b, Drer\pvalb2, Drer\pvalb9, Drer\calm2a, Drer\cabp7b, Drer\si:ch211-197n1.2, Drer\calml4b, Drer\caln2, Drer\calm3b, Drer\caln1, Drer\tnnc1b, Drer\efcab2, Drer\calb2b, Drer\rhbdl3, Drer\cabp2a, Drer\cabp1a, Drer\calm2b, Drer\cabp2b" "Scer\MLC2, Scer\CDC31, Scer\MLC1, Scer\CMD1" "Cele\pat-10, Cele\cal-4, Cele\cmd-1, Cele\cal-1, Cele\cal-2, Cele\cal-3, Cele\tnc-2" "Xtro\cabp4, Xtro\LOC548651, Xtro\scgn, Xtro\pvalb, Xtro\tnnc1, Xtro\calm1, Xtro\pvalb.2, Xtro\pvalb.1, Xtro\efcab6, Xtro\calm2, Xtro\ocm, Xtro\calml4, Xtro\pgm1, Xtro\tnnc2, Xtro\cabp7, Xtro\calb1, Xtro\ocm.2" "Mmus\Efcab9, Mmus\Cabp7, Mmus\Cabp1, Mmus\Calm2, Mmus\Rhbdl3, Mmus\Calm1, Mmus\Efcab11, Mmus\Efcab6, Mmus\Cabp4, Mmus\Tnnc1, Mmus\Calml3, Mmus\Efcab3, Mmus\Tnnc2, Mmus\Calm4, Mmus\1700023F06Rik, Mmus\Efcab7, Mmus\Calb1, Mmus\Calm5, Mmus\Cabp2, Mmus\Calml4, Mmus\Ocm, Mmus\Cabp5, Mmus\Spata21, Mmus\Calb2, Mmus\Pvalb, Mmus\Scgn, Mmus\Calm3, Mmus\Efcab2, Mmus\Caln1" "Hsap\SPATA21, Hsap\TNNC1, Hsap\EFCAB9, Hsap\CABP4, Hsap\CABP2, Hsap\EFCAB6, Hsap\CALML5, Hsap\CABP5, Hsap\CALN1, Hsap\CALML6, Hsap\CALM1, Hsap\CALB2, Hsap\SCGN, Hsap\OCM, Hsap\TNNC2, Hsap\RHBDL3, Hsap\EFCAB13, Hsap\EFCAB2, Hsap\CALM2, Hsap\CABP7, Hsap\OCM2, Hsap\PVALB, Hsap\CALB1, Hsap\EFCAB7, Hsap\CABP1, Hsap\EFCAB3, Hsap\CALM3, Hsap\CALML4, Hsap\EFCAB11, Hsap\CALML3" " embryonic stage | late , larval stage--pupal stage , pupal stage | late , larval stage " organism

"lethal,viable" DRSC07564 K 0.177032847 -0.476977577 0.201616851 -0.132509669 1.738106737 0.313994913 FBgn0030389 CG15927 - http://flybase.org/reports/FBgn0030389 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15927 - CG15927 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC19742 K 0.889012232 -0.21945963 -0.38232951 0.132434878 -0.043419496 1.609891924 FBgn0259150 CG42265 - http://flybase.org/reports/FBgn0259150 protein_coding_gene - - - "CG17758, CG42265, CG15776, CG15777" IPR004878:Otopetrin CG42265 11-Aug-17 DroID_v2017_08 "Drer\otop1, Drer\otop2" - "Cele\otpl-7, Cele\otpl-8, Cele\otpl-6, Cele\otpl-2, Cele\otpl-4, Cele\otpl-3, Cele\otpl-1, Cele\otpl-5" "Xtro\otop3, Xtro\LOC100496487, Xtro\otop2, Xtro\otop1" "Mmus\Otop3, Mmus\Otop2, Mmus\Otop1" "Hsap\OTOP3, Hsap\OTOP2, Hsap\OTOP1" DRSC18083 K -1.070204438 0.947584682 1.309513414 -0.364345181 1.447018039 2.71422256 FBgn0031391 CG11723 - http://flybase.org/reports/FBgn0031391 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - - "CG11723, 11723, CC25" "IPR004210:BESS motif, IPR006578:MADF domain" CG11723 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-207i20.3, Drer\LOC100330838, Drer\zgc:152938" - "Cele\madf-3, Cele\madf-5, Cele\madf-8, Cele\madf-2, Cele\madf-10, Cele\madf-4, Cele\madf-9" - - - viable DRSC00324 K 0.617646205 -0.378682456 -0.450174933 0.069845748 1.66499814 -0.371196172 FBgn0034489 ppk6 pickpocket 6 http://flybase.org/reports/FBgn0034489 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG11209, PPK6, ppk6" IPR001873:Epithelial sodium channel CG11209 11-Aug-17 DroID_v2017_08 "Drer\asic1b, Drer\asic1c, Drer\asic1a, Drer\asic4a, Drer\asic2, Drer\asic4b" - "Cele\degt-1, Cele\asic-1, Cele\flr-1, Cele\del-4, Cele\unc-105, Cele\delm-2, Cele\egas-2, Cele\del-1, Cele\deg-1, Cele\delm-1, Cele\acd-4, Cele\del-10, Cele\mec-4, Cele\unc-8, Cele\egas-1, Cele\mec-10, Cele\acd-2, Cele\egas-3, Cele\egas-4, Cele\acd-1, Cele\acd-5, Cele\asic-2" "Xtro\asic5, Xtro\scnn1a, Xtro\scnn1b, Xtro\scnn1g, Xtro\asic4, Xtro\asic1, Xtro\scnn1d" "Mmus\Scnn1b, Mmus\Asic5, Mmus\Asic3, Mmus\Asic2, Mmus\Scnn1g, Mmus\Asic4, Mmus\Scnn1a, Mmus\Asic1" "Hsap\SCNN1G, Hsap\ASIC1, Hsap\ASIC2, Hsap\ASIC4, Hsap\SCNN1B, Hsap\SCNN1A, Hsap\ASIC3, Hsap\ASIC5, Hsap\SCNN1D" viable DRSC06062 E 0.546940953 -0.064171594 -2.228608228 0.185448126 -0.074169223 -0.225235422 FBgn0035612 frm farmer http://flybase.org/reports/FBgn0035612 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype - "anon-WO0118547.236, CG10625, frm" IPR000618:Insect cuticle protein CG10625 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-106n13.3, Drer\col1a2, Drer\col16a1, Drer\col9a1a, Drer\col6a3, Drer\wu:fc38h03, Drer\col14a1a, Drer\col11a1a, Drer\col17a1a, Drer\zmp:0000000760, Drer\col17a1b, Drer\LOC101884357, Drer\col1a1a, Drer\col12a1b, Drer\col4a4, Drer\col11a2, Drer\col2a1a, Drer\col2a1b, Drer\col7a1l, Drer\col11a1b, Drer\col9a1b, Drer\col5a2b, Drer\col4a5, Drer\col9a2, Drer\si:ch211-196i2.1, Drer\si:dkey-61l1.4, Drer\col1a1b, Drer\LOC100538221, Drer\col6a1, Drer\col28a1a, Drer\LOC101883924, Drer\col4a2, Drer\col6a2, Drer\col4a6, Drer\si:dkey-225n22.4, Drer\col27a1a, Drer\col28a1a, Drer\col5a1, Drer\col6a4a, Drer\zgc:153049, Drer\col5a2a, Drer\col27a1b" - "Cele\col-146, Cele\col-107, Cele\col-45, Cele\col-65, Cele\col-143, Cele\col-178, Cele\col-142, Cele\col-179, Cele\col-88, Cele\col-162, Cele\col-7, Cele\col-111, Cele\col-120, Cele\col-63, Cele\col-98, Cele\cle-1, Cele\rol-8, Cele\col-141, Cele\Y53C10A.10, Cele\dpy-9, Cele\col-39, Cele\dpy-5, Cele\col-156, Cele\col-53, Cele\col-129, Cele\col-140, Cele\col-19, Cele\col-147, Cele\col-91, Cele\col-161, Cele\col-182, Cele\col-80, Cele\col-76, Cele\col-8, Cele\col-62" "Xtro\col4a1, Xtro\col4a6, Xtro\col14a1, Xtro\col24a1, Xtro\col2a1, Xtro\col5a1, Xtro\col27a1, Xtro\col7a1, Xtro\col1a1, Xtro\col3a1, Xtro\LOC100486063, Xtro\col1a2, Xtro\col4a5, Xtro\col6a2, Xtro\col11a2, Xtro\col4a2" "Mmus\Col28a1, Mmus\Col24a1, Mmus\Col19a1, Mmus\Col17a1, Mmus\Vwa1, Mmus\Col3a1, Mmus\Col1a2, Mmus\Col13a1, Mmus\Col4a1, Mmus\Vwa2, Mmus\Col6a6, Mmus\8030474K03Rik, Mmus\Col5a3, Mmus\Col6a3, Mmus\Col20a1, Mmus\Col5a1, Mmus\Col11a2, Mmus\Col4a6, Mmus\Col1a1, Mmus\Col23a1, Mmus\Col6a1, Mmus\Col16a1, Mmus\4933412E24Rik, Mmus\Col5a2, Mmus\Col11a1, Mmus\Col4a4, Mmus\Col9a3, Mmus\Col4a3, Mmus\Col6a4, Mmus\Col4a5, Mmus\Col27a1, Mmus\Tnn, Mmus\Col25a1, Mmus\Col15a1, Mmus\Col22a1, Mmus\Col9a1, Mmus\Col14a1, Mmus\Col6a5, Mmus\Col2a1, Mmus\Col7a1, Mmus\Col26a1, Mmus\Col4a2" "Hsap\COL4A4, Hsap\COL11A2, Hsap\COL20A1, Hsap\COL5A3, Hsap\COL2A1, Hsap\COL6A5, Hsap\COL6A3, Hsap\COL4A5, Hsap\COL5A2, Hsap\COL14A1, Hsap\COL27A1, Hsap\COL6A6, Hsap\COL5A1, Hsap\COL17A1, Hsap\COL16A1, Hsap\COL1A2, Hsap\COL4A1, Hsap\COL9A3, Hsap\COL6A1, Hsap\COL1A1, Hsap\COL15A1, Hsap\COL23A1, Hsap\COL4A3, Hsap\COL4A2, Hsap\COL26A1, Hsap\COL3A1, Hsap\COL4A6, Hsap\COL19A1, Hsap\COL25A1, Hsap\COL9A2, Hsap\COL7A1, Hsap\COL9A1, Hsap\VWA2, Hsap\COL11A1, Hsap\COL22A1, Hsap\COL24A1, Hsap\VWA1, Hsap\COLQ" "viable,fertile" DRSC09753 I -1.510333145 0.78026998 -1.020710596 0.370674381 0.022341458 -0.127971482 FBgn0030477 dmrt11E doublesex-Mab related 11E http://flybase.org/reports/FBgn0030477 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR026607 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001275" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001275, InterPro:IPR026607 spermatogenesis ; GO:0007283 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026607 "Dmrt11E, CG15749, dmrt11E, dmrt11" "IPR001275:DM DNA-binding domain, IPR026607:DMRT/protein doublesex/protein male abnormal 3" CG15749 11-Aug-17 DroID_v2017_08 "Drer\dmrta2, Drer\dmrt2a, Drer\dmrt3a, Drer\dmrt2b" - "Cele\mab-3, Cele\dmd-4, Cele\dmd-10, Cele\dmd-8, Cele\dmd-9, Cele\dmd-5, Cele\dmd-7, Cele\dmd-3, Cele\dmd-6, Cele\dmd-11" "Xtro\kank1, Xtro\dmrta1, Xtro\dmrt3, Xtro\dmrta2" "Mmus\Dmrtc1c1, Mmus\Dmrtb1, Mmus\Dmrt2, Mmus\Dmrta1, Mmus\Dmrt3, Mmus\Dmrtc2, Mmus\Dmrtc1a, Mmus\Dmrta2, Mmus\Dmrt1, Mmus\Dmrtc1c2, Mmus\Dmrtc1b" "Hsap\DMRT1, Hsap\DMRTC1, Hsap\DMRTA1, Hsap\DMRT2, Hsap\DMRTA2, Hsap\DMRTC1B, Hsap\DMRTC2, Hsap\DMRTB1, Hsap\DMRT3" viable DRSC19715 E 1.153486101 0.873040502 1.741670415 0.541979184 0.337053422 0.174427173 FBgn0058099 CG40099 - http://flybase.org/reports/FBgn0058099 protein_coding_gene - - - CG40099 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20786 IE -0.1336491 -2.585119333 -0.045680844 -2.305436801 0.095512157 0.056224184 FBgn0034741 CG4269 - http://flybase.org/reports/FBgn0034741 protein_coding_gene - - - "CG4269, cg4269" - CG4269 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC04457 K 0.388610423 0.24432846 0.590171739 0.032631516 -0.146957915 -1.944911785 FBgn0004924 Top1 Topoisomerase 1 http://flybase.org/reports/FBgn0004924 "FBgn0027237, FBgn0027261, FBgn0027275, FBgn0040195" protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001631, InterPro:IPR008336, InterPro:IPR011010, InterPro:IPR013030, InterPro:IPR013499, InterPro:IPR013500, InterPro:IPR014711, InterPro:IPR014727, InterPro:IPR018521 DNA topoisomerase type I activity ; GO:0003917 | inferred from direct assay DNA topoisomerase activity ; GO:0003916 | inferred from direct assay" oogenesis ; GO:0048477 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from biological aspect of ancestor with PANTHER:PTN000033230 chromosome condensation ; GO:0030261 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype multicellular organism development ; GO:0007275 | inferred from mutant phenotype regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from biological aspect of ancestor with PANTHER:PTN000033230 DNA topological change ; GO:0006265 | inferred from direct assay "nucleus ; GO:0005634 | inferred from direct assay replication fork protection complex ; GO:0031298 | inferred from biological aspect of ancestor with PANTHER:PTN000033230 microtubule associated complex ; GO:0005875 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | colocalizes_with inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay nuclear euchromatin ; GO:0005719 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay" "Topo I, dTopoI, TopI, top1, topo I, TOP1, topoI, l(1)top1, l(1)G0201, l(1)G0229, l(1)G0278, l(1)G0134, CG6146, Top1, TopoI" "IPR025834:Topoisomerase I C-terminal domain, IPR018521:DNA topoisomerase I, active site, IPR013030:DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type, IPR014711:DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type, IPR014727:DNA topoisomerase I, catalytic core, alpha/beta subdomain, IPR001631:DNA topoisomerase I, IPR008336:DNA topoisomerase I, DNA binding, eukaryotic-type, IPR011010:DNA breaking-rejoining enzyme, catalytic core, IPR013499:DNA topoisomerase I, eukaryotic-type, IPR013500:DNA topoisomerase I, catalytic core, eukaryotic-type, IPR013034:DNA topoisomerase I, domain 1" CG6146 11-Aug-17 DroID_v2017_08 "Drer\top1, Drer\top1mt, Drer\zgc:173742, Drer\LOC108179068, Drer\top1l" Scer\TOP1 Cele\top-1 "Xtro\top1.1, Xtro\top1.2" "Mmus\Top1mt, Mmus\Top1" "Hsap\TOP1MT, Hsap\TOP1" " adult stage , embryonic stage , embryonic stage | early , adult stage | female , embryonic stage -- adult stage " ovary

embryonic stage -- adult stage "viable,increased cell death,recessive,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,partially lethal - majority die,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,wild-type,mitotic cell cycle defective,cell death defective,female sterile,visible" "adult brain,nucleusSgs3.PD,wing,chaeta,melanotic mass,dorsal appendage,follicle cell,germarium,mitotic cell cycle, with Top177,nurse cell & nucleus, with Top177,nurse cell,ectopic,oocyte,mitotic cell cycle | embryonic stage 4, with Top177,mitotic telophase | embryonic stage 4, with Top177,nucleus | embryonic stage 4, with Top177,mitotic cell cycle | embryonic stage 4,nucleus | embryonic stage 4,mitotic cell cycle, with Top1hs.2,nurse cell & nucleus, with Top1hs.2,mitotic cell cycle | embryonic stage 4, with Top1hs.2,mitotic telophase | embryonic stage 4, with Top1hs.2,nucleus | embryonic stage 4, with Top1hs.2,larva,imaginal disc,supernumerary" DRSC20295 I -1.321326334 -2.082754561 -1.30813623 -0.944303279 0.10932181 0.347720493 FBgn0000047 Act88F Actin 88F http://flybase.org/reports/FBgn0000047 - protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity skeletal myofibril assembly ; GO:0014866 | inferred from mutant phenotype muscle thin filament assembly ; GO:0071689 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype actin filament ; GO:0005884 | inferred from sequence or structural similarity "Actin, Act88F, actin, E, act88F, CG5178, Act(88F), act 88F, Act88-F, Ifm(3)7, rsd, Act88f, ArpD" "IPR004000:Actin family, IPR004001:Actin, conserved site, IPR020902:Actin/actin-like conserved site" CG5178 11-Aug-17 DroID_v2017_08 "Drer\acta1b, Drer\si:ch73-187m15.4, Drer\acta1a, Drer\ankrd52b, Drer\actr10, Drer\actc1a, Drer\actc1b, Drer\acta2, Drer\actb2, Drer\zgc:86725, Drer\actb1, Drer\si:ch211-241j12.3, Drer\zgc:86709, Drer\actr1" "Scer\ARP1, Scer\ACT1, Scer\ARP9, Scer\ARP2" "Cele\act-1, Cele\arp-1, Cele\act-4, Cele\act-5, Cele\act-2, Cele\act-3, Cele\arx-2" "Xtro\acta2, Xtro\acta1, Xtro\actr1a, Xtro\actb, Xtro\actg1, Xtro\ankrd52, Xtro\act3, Xtro\actc1, Xtro\actr10" "Mmus\Actr10, Mmus\Actrt2, Mmus\Acta2, Mmus\Actc1, Mmus\Actr2, Mmus\Acta1, Mmus\Actb, Mmus\Actl9, Mmus\Actr1a, Mmus\Actl7a, Mmus\Actl10, Mmus\Actg2, Mmus\Actl11, Mmus\Actrt3, Mmus\Actg1, Mmus\Actrt1, Mmus\Actr1b, Mmus\Actbl2, Mmus\Actl7b" "Hsap\POTEH, Hsap\ACTG2, Hsap\POTEI, Hsap\POTEB2, Hsap\POTEE, Hsap\ACTG1, Hsap\ACTL10, Hsap\ACTR1B, Hsap\POTED, Hsap\ACTL9, Hsap\ACTB, Hsap\POTEF, Hsap\ACTRT2, Hsap\POTEG, Hsap\ACTR2, Hsap\ACTR1A, Hsap\ACTA2, Hsap\ACTL8, Hsap\ACTR10, Hsap\ACTBL2, Hsap\POTEJ, Hsap\ACTL7A, Hsap\ACTRT3, Hsap\POTEC, Hsap\POTEB, Hsap\ACTC1, Hsap\ACTRT1, Hsap\POTEA, Hsap\ACTA1, Hsap\ACTL7B" pupal stage adult stage indirect flight muscle

"flightless,dominant,flight defective,wild-type,semidominant,cold sensitive,visible,recessive,female fertile,reduced,locomotor behavior defective,viable,lethal" "striated muscle thin filament,indirect flight muscle,myofibril,wing,sarcomere,dorsal medial muscle,indirect flight muscle & striated muscle thick filament,indirect flight muscle & striated muscle thin filament,indirect flight muscle & muscle tendon junction,tendon cell,myofibril, with Act88FG15R,Z disc, with Act88FG15R,myofibril, with Act88FI136M,Z disc, with Act88FI136M,myofibril, with Act88FD154N,Z disc, with Act88FD154N,myofibril, with Act88FV163L,Z disc, with Act88FV163L,myofibril, with Act88FV163M,Z disc, with Act88FV163M,myofibril, with Act88FD292V,Z disc, with Act88FD292V,indirect flight muscle & nucleus,myofibril, with Act88F6,Z disc, with Act88F6" DRSC14105 IE -1.848094117 0.269109048 -0.103332891 -1.676953269 1.383607201 1.347735904 FBgn0000459 disco disconnected http://flybase.org/reports/FBgn0000459 "FBtr0074250, FBpp0074028" protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay "photoreceptor cell maintenance ; GO:0045494 | non-traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype eclosion rhythm ; GO:0008062 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype antennal development ; GO:0007469 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "disco, disc, CG9908, Disco, DISCO" IPR013087:Zinc finger C2H2-type CG9908 11-Aug-17 DroID_v2017_08 "Drer\bnc2, Drer\bnc1" - Cele\bnc-1 "Xtro\bnc1, Xtro\bnc2" "Mmus\Bnc1, Mmus\Bnc2" "Hsap\BNC1, Hsap\BNC2" " embryonic stage | stage 6 , embryonic stage | stage 15 , embryonic stage | >=6 hr , embryonic stage | stage 11-14 , larval stage--adult stage , embryonic stage | stage 12-15 , embryonic stage | stage 5 , embryonic stage | stage 11 , adult stage , embryonic stage | stage 11-15 , larval stage | third instar " " dorsal ectoderm | restricted

, cephalic furrow | anterior to

, ventral nerve cord

, procephalic segment | restricted

, abdominal segment | ectoderm of

, thoracic segment | ectoderm of

, visceral mesoderm

, amnioproctodeal invagination

,

posterior , proctodeum

, adult head

, gnathal segment

, embryonic optic lobe primordium

, larval brain | restricted

,

0-10% egg length , imaginal disc

, labral segment

" " embryonic stage | stage 6 , larval stage | third instar , embryonic stage | stage 10 , embryonic stage | stage 15 , embryonic stage | stage 13 , embryonic stage | stage 12-15 , embryonic stage | stage 13-15 , embryonic stage | stage 5 , embryonic stage | stage 12-14 " " cephalic furrow | anterior to

, larval brain | restricted

, amnioproctodeal invagination

, proctodeum

, embryonic optic lobe primordium

, thoracic segment | restricted

, cephalic furrow | posterior to

, labral segment

, visceral mesoderm

, larval optic stalk

, antennal disc

, cardioblast

, lateral ectoderm | segmentally repeated

, ventral nerve cord

, gnathal segment

, ventral thoracic disc

,

0-10% egg length , procephalic segment | restricted

,

posterior , central nervous system | restricted

" "viable,lethal,some die during larval stage,some die during P-stage,partially lethal,temperature conditional,homeotic,circadian rhythm defective,visual behavior defective,recessive,behavior defective,wild-type,mating rhythm defective,female limited,locomotor rhythm defective,locomotor behavior defective,visible,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,fertile" "antenna,leg,tarsal segment,temperature conditional,unguis,third segment of antenna,arista,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,optic lobe,precursor,optic nerve,femur,tibia,lamina,neuron,multidendritic neuron,sensory neuron & leg,sensory neuron & wing,sensory neuron & haltere,central nervous system,prothoracic neuromere,mesothoracic neuromere,metathoracic neuromere,chordotonal organ,mouth hooks,embryonic/larval optic stalk,eye photoreceptor cell & axon & larva,LN Pdf neuron,Pdf neuron close to calyx,l-LNv neuron,Pdf neuron close to tritocerebrum,LNv neuron,eye,ommatidium,pigment cell,cone cell,interommatidial bristle,abdominal ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,prothoracic ventral denticle belt,extended germ band embryo,dorsal closure embryo,cephalopharyngeal skeleton" FBgn0023495 Lip3 Lip3 http://flybase.org/reports/FBgn0023495 - protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - "lip3, Dmlip3, LIP3, CG8823, Lip3, dLip3, LIP3Dm, dilp3" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG8823 11-Aug-17 DroID_v2017_08 Drer\lipf "Scer\TGL1, Scer\YEH2, Scer\YEH1" "Cele\lipl-7, Cele\lipl-6, Cele\lipl-8, Cele\lipl-4, Cele\lipl-1, Cele\lipl-2, Cele\lipl-3, Cele\lipl-5" Xtro\lipa "Mmus\Lipk, Mmus\Lipo3, Mmus\Lipa, Mmus\Lipm, Mmus\Lipo2, Mmus\Lipo4, Mmus\Lipo1, Mmus\Lipf, Mmus\Lipn" "Hsap\LIPJ, Hsap\LIPF, Hsap\LIPK, Hsap\LIPA, Hsap\LIPN, Hsap\LIPM" " larval stage | first instar , adult stage | female , oogenesis stage | stage S10 , larval stage | second instar , larval stage , embryonic stage " "

late , ovary

, follicle cell

, embryonic/larval fat body

, oocyte

" viable FBgn0000181 bic bicaudal http://flybase.org/reports/FBgn0000181 "FBgn0002068, FBgn0004676, FBgn0021942, FBgn0027918" protein_coding_gene protein transporter activity ; GO:0008565 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q94518 regulation of establishment of protein localization ; GO:0070201 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype intracellular mRNA localization involved in anterior/posterior axis specification ; GO:0060811 | inferred from mutant phenotype protein transport ; GO:0015031 | traceable author statement regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype nascent polypeptide-associated complex ; GO:0005854 | inferred from sequence or structural similarity with SGD:S000002660 microtubule associated complex ; GO:0005875 | inferred from direct assay "Bic, CG3644, l(2)k10712, 5A, BcDNA.GM05329, Btf, 107/12, vr22, l(2)49Da, E(Bic), l(2)vr22, E(2)Bic, BcDNA:GM05329, bic" IPR002715:Nascent polypeptide-associated complex NAC domain CG3644 11-Aug-17 DroID_v2017_08 "Drer\btf3, Drer\btf3l4, Drer\tab3, Drer\tab2" "Scer\EGD1, Scer\BTT1, Scer\WWM1, Scer\YML020W" Cele\icd-1 "Xtro\btf3, Xtro\btf3l4" "Mmus\Btf3l4, Mmus\Tab3, Mmus\Tab2, Mmus\Btf3" "Hsap\BTF3, Hsap\TAB3, Hsap\BTF3L4, Hsap\TAB2" " embryonic stage | late , adult stage && oogenesis stage , adult stage | female , adult stage | male , embryonic stage , embryonic stage | stage <=8 , adult stage && oogenesis stage | stage S3-10 , adult stage && oogenesis stage | stage >=S10 , embryonic stage | extended germ band " " pharyngeal muscle

, germarium region 2b

, embryonic/larval somatic muscle | subset

, embryonic central nervous system

, ovary

, organism

, nurse cell

, oocyte

, mesoderm

" "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,dominant,wild-type,maternal effect,non-suppressor of variegation,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,embryo,anterior,egg,embryonic head,embryonic segment,maternal effect,denticle belt,embryonic/larval posterior spiracle,Malpighian tubule,genital disc,amnioproctodeal invagination,cephalopharyngeal skeleton" FBgn0260400 elav embryonic lethal abnormal vision http://flybase.org/reports/FBgn0260400 protein_coding_gene "mRNA binding ; GO:0003729 | non-traceable author statement poly(U) RNA binding ; GO:0008266 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity translation repressor activity, nucleic acid binding ; GO:0000900 | non-traceable author statement RNA binding ; GO:0003723 | inferred from direct assay" negative regulation of mRNA 3'-end processing ; GO:0031441 | inferred from direct assay nervous system development ; GO:0007399 | non-traceable author statement germ cell development ; GO:0007281 | non-traceable author statement negative regulation of oskar mRNA translation ; GO:0007319 | non-traceable author statement embryo development ; GO:0009790 | non-traceable author statement central nervous system development ; GO:0007417 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement Cajal body ; GO:0015030 | inferred from direct assay "Elav, ELAV, ElaV, elav, weg, Elav-9F8A9, 9F8A9, CG4262, EG:65F1.2, l(1)G0319, l(1)G0031, l(1)1Be, elav-3, elav-2, elav-1, EC7, l(1)EC7, fliJ, 44C11, END1-2, dHuR" "IPR000504:RNA recognition motif domain, IPR002343:Paraneoplastic encephalomyelitis antigen, IPR006548:Splicing factor ELAV/HuD" CG4262 11-Aug-17 DroID_v2017_08 "Drer\rbms3, Drer\elavl1, Drer\rbms1a, Drer\rbms2b, Drer\nol8, Drer\elavl3, Drer\hug, Drer\elavl4, Drer\elavl2, Drer\rbms2a" "Scer\SEC26, Scer\PAB1, Scer\GBP2" "Cele\tag-325, Cele\copb-1, Cele\exc-7, Cele\zyg-1" "Xtro\elavl4, Xtro\elavl2, Xtro\elavl3, Xtro\elavl1" "Mmus\Elavl3, Mmus\Elavl4, Mmus\Elavl1, Mmus\Rbms1, Mmus\Elavl2, Mmus\Rbms2, Mmus\Rbms3, Mmus\Copb1" "Hsap\ELAVL4, Hsap\ELAVL3, Hsap\RBMS3, Hsap\COPB1, Hsap\ELAVL2, Hsap\ELAVL1, Hsap\RBMS1, Hsap\RBMS2" " embryonic stage | stage 13-14 , embryonic stage| 6-18 hr , embryonic stage , adult stage , larval stage | third instar , embryonic stage | stage 11-14 , embryonic stage | 6-18 hr , embryonic stage | 6-12 hr , pharate adult stage | stage P15 " " dorsal ectoderm

segmentally repeated , Johnston's organ

, ventral nerve cord

, embryonic central nervous system | presumptive

, embryonic nervous system

, morphogenetic furrow | posterior to

, thoracico-abdominal ganglion

, larval brain

" " pupal stage | 12-50 hr , adult stage , pupal stage | 72 hr , pupal stage | 12 hr , embryonic stage | stage 11-16 , larval stage | third instar , pupal stage | stage P9 , embryonic stage | stage 13-15 , pupal stage--adult stage , embryonic stage | stage 11-15 " " ocellus | presumptive

, photoreceptor cell R1--8

, ocellus

, retina

, lamina cortex

, lobula plate cortex

, eye-antennal disc

, embryonic/larval nervous system

, thoracico-abdominal ganglion

, monopolar laminar cell

, larval brain

, peripheral nervous system

, eye

, medulla cortex

, adult brain

, central nervous system

, antenna

" FBgn0016075 vkg viking http://flybase.org/reports/FBgn0016075 FBgn0010477 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from electronic annotation with InterPro:IPR001442 skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype collagen trimer ; GO:0005581 | inferred from electronic annotation with InterPro:IPR001442 lipid particle ; GO:0005811 | inferred from direct assay collagen type IV trimer ; GO:0005587 | non-traceable author statement "vkg, CT25584, alpha(IV)2/vkg, DmColA2, 6072, 1209, l(2)01209, CG16858, coll. IV, Vkg, Coll IValpha2, col4a2, VkgC, collagen-IV, coll-IV, Coll IV" "IPR001442:Collagen IV, non-collagenous, IPR008160:Collagen triple helix repeat, IPR016187:C-type lectin fold" CG16858 11-Aug-17 DroID_v2017_08 "Drer\col11a1b, Drer\si:dkey-225n22.4, Drer\col6a2, Drer\col1a1b, Drer\col12a1b, Drer\col5a2a, Drer\col28a1b, Drer\col17a1b, Drer\col4a1, Drer\col6a3, Drer\si:ch211-196i2.1, Drer\si:ch211-106n13.3, Drer\col11a2, Drer\col27a1a, Drer\col7a1l, Drer\col4a2, Drer\col4a5, Drer\LOC101884357, Drer\col5a2b, Drer\col16a1, Drer\col9a1a, Drer\LOC100538221, Drer\col1a2, Drer\wu:fc38h03, Drer\col27a1b, Drer\si:dkey-61l1.4, Drer\zgc:153049, Drer\col2a1b, Drer\col9a1b, Drer\col11a1a, Drer\col28a1a, Drer\col2a1a, Drer\col1a1a, Drer\col6a1, Drer\col14a1a, Drer\col9a2, Drer\col4a6, Drer\LOC101883924, Drer\col5a1, Drer\col6a4a, Drer\col15a1b" - "Cele\col-121, Cele\let-2, Cele\col-131, Cele\emb-9" "Xtro\col27a1, Xtro\col2a1, Xtro\col14a1, Xtro\col11a2, Xtro\col6a2, Xtro\col1a1, Xtro\col4a1, Xtro\col24a1, Xtro\col1a2, Xtro\col4a2, Xtro\col7a1, Xtro\LOC100486063, Xtro\col3a1, Xtro\col5a1, Xtro\col4a6, Xtro\col4a5" "Mmus\Col28a1, Mmus\Col23a1, Mmus\Col6a4, Mmus\Col6a3, Mmus\Col22a1, Mmus\Col4a4, Mmus\Col9a3, Mmus\Col1a2, Mmus\Col4a3, Mmus\Col6a1, Mmus\Col1a1, Mmus\Col4a6, Mmus\Tnn, Mmus\Col17a1, Mmus\Col4a5, Mmus\8030474K03Rik, Mmus\Col9a1, Mmus\Col5a1, Mmus\Col2a1, Mmus\Vwa2, Mmus\Col20a1, Mmus\4933412E24Rik, Mmus\Col3a1, Mmus\Col6a6, Mmus\Vwa1, Mmus\Col4a2, Mmus\Col27a1, Mmus\Col5a2, Mmus\Col4a1, Mmus\Col16a1, Mmus\Col13a1, Mmus\Col6a5, Mmus\Col14a1, Mmus\Col19a1, Mmus\Col7a1, Mmus\Col25a1, Mmus\Col11a1, Mmus\Col24a1, Mmus\Col11a2, Mmus\Col5a3" "Hsap\COL20A1, Hsap\COL11A2, Hsap\COL19A1, Hsap\COL6A6, Hsap\COL23A1, Hsap\COL4A3, Hsap\COL4A5, Hsap\COL7A1, Hsap\COL4A4, Hsap\COL5A1, Hsap\COL17A1, Hsap\VWA2, Hsap\COL6A3, Hsap\COL11A1, Hsap\COL25A1, Hsap\COL3A1, Hsap\COL27A1, Hsap\COL24A1, Hsap\COL9A3, Hsap\COL2A1, Hsap\COL4A6, Hsap\COL6A1, Hsap\COLQ, Hsap\COL16A1, Hsap\COL6A5, Hsap\COL9A2, Hsap\COL4A2, Hsap\COL4A1, Hsap\COL9A1, Hsap\COL22A1, Hsap\COL1A1, Hsap\COL1A2, Hsap\COL5A3, Hsap\VWA1, Hsap\COL5A2, Hsap\COL14A1" " embryonic stage | stage 16-17 , embryonic stage | stage 15-16 , larval stage | first instar " " embryonic/larval fat body

, embryonic/larval hemocyte

" "viable,lethal,recessive,short lived,hypoactive,locomotor behavior defective" "embryonic anterior Malpighian tubule,A1-7 segment border muscle" FBgn0036964 FRG1 FSHD region gene 1 http://flybase.org/reports/FBgn0036964 protein_coding_gene actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000309119 negative regulation of histone H4-K20 methylation ; GO:0070511 | inferred from mutant phenotype negative regulation of chromatin silencing ; GO:0031936 | inferred from genetic interaction with Hmt4-20 catalytic step 2 spliceosome ; GO:0071013 | inferred from biological aspect of ancestor with PANTHER:PTN000309119 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000309119 cytoplasm ; GO:0005737 | inferred from direct assay striated muscle dense body ; GO:0055120 | inferred from biological aspect of ancestor with PANTHER:PTN000309119 "DmFRG1, CG6480, FRG1, dFRG1" "IPR008999:Actin cross-linking, IPR010414:Protein FRG1" CG6480 11-Aug-17 DroID_v2017_08 Drer\frg1 - Cele\frg-1 Xtro\frg1 Mmus\Frg1 Hsap\FRG1 "viable,enhancer of variegation" DRSC10648 K 0.291032651 0.214827884 -0.123849426 0.339932328 1.802058547 -0.240082729 FBgn0001325 Kr Kruppel http://flybase.org/reports/FBgn0001325 "FBgn0001251, FBgn0015732" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay" "compound eye development ; GO:0048749 | inferred from mutant phenotype ganglion mother cell fate determination ; GO:0007402 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay regulation of development, heterochronic ; GO:0040034 | traceable author statement chromatin silencing ; GO:0006342 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay trunk segmentation ; GO:0035290 | traceable author statement Malpighian tubule bud morphogenesis ; GO:0061332 | inferred from genetic interaction with ct neuroblast fate determination ; GO:0007400 | inferred from expression pattern inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | traceable author statement regulation of development, heterochronic ; GO:0040034 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype muscle organ development ; GO:0007517 | traceable author statement Malpighian tubule morphogenesis ; GO:0007443 | traceable author statement wing disc development ; GO:0035220 | inferred from genetic interaction with Bx zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | non-traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from direct assay ventral cord development ; GO:0007419 | non-traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "Kr, kr, CG3340, If, Kruppel, Dm-Kr, KR" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3340 11-Aug-17 DroID_v2017_08 "Drer\zgc:110821, Drer\si:dkey-111k8.5, Drer\LOC103908664, Drer\zgc:171599, Drer\zgc:172128, Drer\LOC101884528, Drer\zgc:175284, Drer\si:ch73-299h12.4, Drer\si:dkey-77f5.4, Drer\LOC100536348, Drer\znf1144, Drer\LOC108182329, Drer\si:dkey-77f5.8, Drer\LOC103911440, Drer\bcl6a, Drer\zgc:113209, Drer\si:ch73-299h12.8, Drer\zgc:112977, Drer\LOC100538160, Drer\zgc:173577, Drer\LOC101883486, Drer\zgc:113886, Drer\zgc:113220, Drer\znf1184, Drer\zgc:171604, Drer\LOC103911361, Drer\zgc:173726, Drer\znf45l, Drer\si:ch211-235i11.4, Drer\zgc:173517, Drer\si:ch73-144d13.7, Drer\znf1160, Drer\si:ch73-144d13.5, Drer\si:dkey-1b17.2, Drer\zgc:100951, Drer\LOC100536030, Drer\si:ch211-241b2.1, Drer\LOC572670, Drer\zgc:173480, Drer\zgc:174224, Drer\zgc:113102, Drer\znf1153, Drer\LOC100330321, Drer\bcl6ab, Drer\znf1162, Drer\znf1168, Drer\znfl2a, Drer\LOC100537032, Drer\zgc:173816, Drer\LOC100330452, Drer\LOC557537" "Scer\AZF1, Scer\YPR015C, Scer\CMR3" Cele\B0310.2 Xtro\bcl6 "Mmus\Bcl6, Mmus\Bcl6b, Mmus\Sp5" "Hsap\ZFP64, Hsap\BCL6, Hsap\ZNF131, Hsap\ZNF554, Hsap\BCL6B" " embryonic stage | stage 14 , embryonic stage | stage 4-10 , embryonic stage | stage >=12 , embryonic stage | blastoderm , embryonic stage | early , embryonic stage--pupal stage , embryonic stage | stage 4 " " embryonic brain

, Bolwig's organ

, embryonic/larval nervous system

, organism | 40-60% egg length

,

medial , embryonic/larval muscle system

,

40-60% egg length " " embryonic stage | stage 13 , embryonic stage | stage 4 , embryonic stage | stage > 9 " " embryonic Malpighian tubule tip cell

, adult muscle precursor primordium | restricted

,

40-60% egg length , embryonic Malpighian tubule

" "visible,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective,heat sensitive,viable,melanotic mass phenotype" "embryonic/larval posterior Malpighian tubule,embryonic/larval anterior Malpighian tubule,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,eye,embryonic segment,embryonic abdominal segment 4,embryonic/larval hemocyte | third instar larval stage,mesothoracic segment,metathoracic segment,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,embryonic prothoracic segment,embryonic abdominal segment 5,embryonic/larval ureter,embryonic/larval Malpighian tubule,embryonic/larval midgut,posterior,embryonic/larval hindgut,Malpighian tubule,extended germ band embryo,Malpighian tubule tip cell,U3 neuron,ectopic,heat sensitive,A1-7 dorsal acute muscle 1,A1-7 lateral longitudinal muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 4,A1-7 ventral acute muscle 2,A1-7 ventral oblique muscle 2,A1-7 ventral oblique muscle 5,mesoderm,ganglion mother cell GMC1-1a,EW2 neuron,EW1 neuron,EW3 neuron,neuroblast NB7-1,abdominal segment 6,abdominal segment 7,ommatidium,eye disc,rhabdomere,adult cuticle,embryonic abdomen,anterior,Malpighian tubule primordium,midgut constriction,embryonic/first instar larval cuticle,larval thorax,larval abdomen,thorax,abdomen,larval abdominal segment,commissure,longitudinal connective,serotonergic neuron,glial cell,larval mesothoracic segment,adult mesothoracic segment,embryonic abdominal segment,embryonic Malpighian tubule,retina,ventral,neuroblast NB7-3,RP neuron,abdominal segmental nerve,A1-7 lateral transverse muscle,abdominal 2 ventral acute muscle 1,abdominal 3 ventral acute muscle 1,abdominal 4 ventral acute muscle 1,abdominal 5 ventral acute muscle 1,abdominal 6 ventral acute muscle 1,abdominal 7 ventral acute muscle 1,lamellocyte | third instar larval stage" DRSC04622 E 0.672396289 0.475605192 2.818499435 -0.015846986 -0.409549783 -0.406273937 FBgn0023458 Rbcn-3A Rabconnectin-3A http://flybase.org/reports/FBgn0023458 FBgn0015656 protein_coding_gene - "lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from biological aspect of ancestor with PANTHER:PTN000359150 vacuolar acidification ; GO:0007035 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype" RAVE complex ; GO:0043291 | inferred from biological aspect of ancestor with PANTHER:PTN000359150 "DmX, X, anon-X, Dmx, Rbcn-3A, FV10, CG3585" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR022033:RAVE complex protein Rav1 C-terminal" CG3585 11-Aug-17 DroID_v2017_08 "Drer\LOC100333625, Drer\LOC100537613, Drer\dmxl2" Scer\RAV1 Cele\rbc-1 "Xtro\dmxl1, Xtro\dmxl2" "Mmus\Dmxl1, Mmus\Dmxl2" "Hsap\DMXL2, Hsap\DMXL1" "lethal,recessive" "follicle cell,somatic clone,tracheal system" DRSC28199 K 0.228527559 0.371090088 0.262247897 -0.954628277 0.023753493 2.893083909 FBgn0021967 ND-PDSW NADH dehydrogenase (ubiquinone) PDSW subunit http://flybase.org/reports/FBgn0021967 "FBgn0027663, FBgn0031539, FBgn0062981" protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from sequence or structural similarity NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O96000 "neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O96000 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN001405974 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O96000 "l(2)k10101, anon-EST:Posey91, CG8844, BcDNA:RE65754, pdsw, PDSW, Pdsw, NIDM, ND-PDSW" "IPR019377:NADH-ubiquinone oxidoreductase, subunit 10" CG8844 11-Aug-17 DroID_v2017_08 Drer\ndufb10 - Cele\F59C6.5 Xtro\ndufb10 Mmus\Ndufb10 Hsap\NDUFB10 "lethal,recessive,visible,somatic clone,neuroanatomy defective,viable,increased cell number" "eye,somatic clone,eye disc,lens,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,lamellocyte | third instar larval stage" DRSC00715 E 1.117392107 0.166467193 1.702471519 -1.287106062 1.262416431 0.174012208 FBgn0260934 par-1 par-1 http://flybase.org/reports/FBgn0260934 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement tau-protein kinase activity ; GO:0050321 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with WB:WBGene00003916" "establishment of cell polarity ; GO:0030010 | inferred from electronic annotation with InterPro:IPR033624 germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay border follicle cell delamination ; GO:0030709 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype oocyte microtubule cytoskeleton organization ; GO:0016325 | traceable author statement regulation of polarized epithelial cell differentiation ; GO:0030860 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | traceable author statement oocyte nucleus localization involved in oocyte dorsal/ventral axis specification ; GO:0051663 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement regulation of Wnt signaling pathway ; GO:0030111 | traceable author statement oocyte differentiation ; GO:0009994 | traceable author statement positive regulation of hippo signaling ; GO:0035332 | inferred from mutant phenotype inferred from genetic interaction with ft inferred from genetic interaction with sd inferred from genetic interaction with ex inferred from genetic interaction with wts inferred from genetic interaction with yki inferred from genetic interaction with sav inferred from physical interaction with sav inferred from physical interaction with hpo synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement microtubule cytoskeleton organization involved in establishment of planar polarity ; GO:0090176 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | traceable author statement maintenance of protein location ; GO:0045185 | traceable author statement oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype axis specification ; GO:0009798 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of protein phosphorylation ; GO:0001933 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype anterior/posterior axis specification ; GO:0009948 | traceable author statement" cell cortex ; GO:0005938 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay type I terminal bouton ; GO:0061174 | inferred from direct assay germline ring canal ; GO:0045172 | inferred from direct assay "par1, par-1, Par-1, PAR1, PAR-1, l(2)27C1, dPAR1, Par1, DPar1, l(2)k06323, dPAR-1, DPAR-1, CG8201, CG11960, CG30131, BcDNA:RH48823, CG16701, CG30132, anon-WO0210402.19, dPar-1, EMK, MARK, 27C1, dPar1, dMARK" "IPR028375:KA1 domain/Ssp2, C-terminal, IPR015940:Ubiquitin-associated domain, IPR000719:Protein kinase domain, IPR001772:Kinase associated domain 1 (KA1), IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR033624:Serine/threonine-protein kinase MARK/par1" CG8201 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-31m14.7, Drer\sik2b, Drer\mark3b, Drer\prkaa1, Drer\sik2a, Drer\mark1, Drer\mark2a, Drer\mark4a, Drer\mark3a, Drer\sik1, Drer\mark2b" "Scer\KIN1, Scer\PRR1, Scer\MRK1, Scer\KIN2, Scer\SNF1" "Cele\par-1, Cele\Y106G6A.1" "Xtro\mark4, Xtro\mark3, Xtro\prkaa2, Xtro\prkaa1, Xtro\mark2, Xtro\sik2, Xtro\sik3" "Mmus\Gm6729, Mmus\Gm14147, Mmus\Gm5174, Mmus\Mark2, Mmus\Sik1, Mmus\Gm4567, Mmus\Smok3a, Mmus\Gm5891, Mmus\Mark3, Mmus\Smok2a, Mmus\Map3k2, Mmus\Sik2, Mmus\Gm10662, Mmus\Mark1, Mmus\Prkaa2, Mmus\Gm6882, Mmus\Gm10668, Mmus\1810024B03Rik, Mmus\Sik3, Mmus\Prkaa1, Mmus\Gm4922, Mmus\Gm4565, Mmus\4921509C19Rik, Mmus\Gm14151, Mmus\Gm6176, Mmus\Gm6902, Mmus\Mark4, Mmus\Gm5157, Mmus\Smok3b, Mmus\Smok2b, Mmus\Gm7168" "Hsap\MARK2, Hsap\MARK3, Hsap\MARK4, Hsap\MARK1, Hsap\SIK3, Hsap\SIK1, Hsap\SIK2, Hsap\MAP3K2, Hsap\PRKAA1, Hsap\PRKAA2" adult stage && oogenesis stage " follicle cell

, oocyte

, nurse cell

" ", adult stage && oogenesis stage | stage S9,10 , oogenesis stage && adult stage | female , adult stage && oogenesis stage , adult stage | female && oogenesis stage | stage S9 , adult stage | female && oogenesis stage | stage S10 " " germarium region 2b && presumptive oocyte | anterior , oocyte | anterior posterior gradient , germarium

, nurse cell ring canal

, stage S3 oocyte

posterior , oocyte | anterior

, follicle cell

, germarium region 1 | ubiquitous & female germline stem cell | ubiquitous

, germarium region 3 && stage S1 oocyte | posterior , germarium region 1 && cystoblast , oocyte | posterior

, stage S5 oocyte

posterior " DRSC07660 K -0.730142184 -1.328089399 -0.169754279 -1.39658169 1.338142879 1.684718003 FBgn0025678 CaBP1 calcium-binding protein 1 http://flybase.org/reports/FBgn0025678 "FBgn0027896, FBgn0028505" protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from sequence or structural similarity protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017937 positive regulation of apoptotic cell clearance ; GO:2000427 | inferred from direct assay inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000432607 response to endoplasmic reticulum stress ; GO:0034976 | inferred from biological aspect of ancestor with PANTHER:PTN000432607" lipid particle ; GO:0005811 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CaBP1, AAL28897, CG5809, BG:DS09218.4, DmCaBP1" "IPR005788:Disulphide isomerase, IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017937:Thioredoxin, conserved site" CG5809 11-Aug-17 DroID_v2017_08 "Drer\pdia6, Drer\dnajc10, Drer\txndc5, Drer\txndc16, Drer\erp27" "Scer\MPD1, Scer\EPS1, Scer\MPD2" "Cele\Y49E10.4, Cele\dnj-27, Cele\pdi-6" "Xtro\txndc5, Xtro\pdia6, Xtro\txndc16" "Mmus\Dnajc10, Mmus\Erp27, Mmus\Txndc16, Mmus\Txndc5, Mmus\Pdia5, Mmus\Pdia6" "Hsap\ERP27, Hsap\PDIA6, Hsap\TXNDC5, Hsap\DNAJC10, Hsap\PDILT, Hsap\PDIA5, Hsap\TXNDC16" " embryonic stage , embryonic stage | stage 5 , embryonic stage | stage >=6 , embryonic stage | extended germ band , embryonic stage | syncytial blastoderm , embryonic stage | stage >8 " " embryonic/larval muscle system

, organism | striped

, ventral midline

,

anterior , embryonic head | posterior

,

posterior ,

ubiquitous " "viable,fertile" FBgn0033027 TpnC4 Troponin C isoform 4 http://flybase.org/reports/FBgn0033027 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 flight ; GO:0060361 | inferred from mutant phenotype - "CG12408, TnC, DmTpnCIIIb, DmTpnC41F, TpnC IIIb, DmTnC4, tnC4, BcDNA:RH03361, TpnC4, TpnC41F, TnC4, TpnCIIIb, TNC41F6, Tnc4, tpnc4" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG12408 11-Aug-17 DroID_v2017_08 "Drer\cabp4, Drer\tnnc1b, Drer\cabp5a, Drer\tnnc1a, Drer\pvalb1, Drer\pvalb4, Drer\tnnc2, Drer\calm3a, Drer\pvalb8, Drer\cabp2b, Drer\pvalb6, Drer\calm2a, Drer\rhbdl3, Drer\cabp7b, Drer\calm1a, Drer\calm1b, Drer\cabp1a, Drer\calb1, Drer\scgn, Drer\cabp2a, Drer\si:ch211-197n1.2, Drer\calm2b, Drer\caln1, Drer\calm3b, Drer\caln2, Drer\pvalb9, Drer\cabp1b, Drer\calb2a, Drer\efcab11, Drer\calml4b, Drer\efcab6, Drer\pvalb2, Drer\efcab2, Drer\calb2b, Drer\cabp5b, Drer\calml4a, Drer\pvalb3" "Scer\CDC31, Scer\CMD1, Scer\MLC1, Scer\MLC2" "Cele\pat-10, Cele\cal-4, Cele\cal-1, Cele\tnc-2, Cele\cal-3, Cele\cal-2, Cele\cmd-1" "Xtro\scgn, Xtro\pvalb.1, Xtro\ocm, Xtro\efcab6, Xtro\pvalb, Xtro\tnnc1, Xtro\ocm.2, Xtro\cabp4, Xtro\calml4, Xtro\calm2, Xtro\LOC548651, Xtro\pgm1, Xtro\calm1, Xtro\calb1, Xtro\cabp7, Xtro\tnnc2, Xtro\pvalb.2" "Mmus\Cabp1, Mmus\Efcab2, Mmus\Calb1, Mmus\Calm3, Mmus\Efcab9, Mmus\Pvalb, Mmus\Cabp2, Mmus\Cabp4, Mmus\Calml3, Mmus\Tnnc2, Mmus\Calm2, Mmus\Rhbdl3, Mmus\Efcab7, Mmus\Calml4, Mmus\Caln1, Mmus\Spata21, Mmus\Efcab6, Mmus\Efcab11, Mmus\Cabp7, Mmus\Cabp5, Mmus\Tnnc1, Mmus\Calm5, Mmus\Calm1, Mmus\Ocm, Mmus\1700023F06Rik, Mmus\Calb2, Mmus\Calm4, Mmus\Scgn, Mmus\Efcab3" "Hsap\TNNC2, Hsap\CALN1, Hsap\CALB1, Hsap\EFCAB7, Hsap\CABP5, Hsap\CALM1, Hsap\CALM2, Hsap\RHBDL3, Hsap\EFCAB11, Hsap\CABP2, Hsap\CABP7, Hsap\EFCAB9, Hsap\EFCAB3, Hsap\SPATA21, Hsap\CALM3, Hsap\CALML5, Hsap\CALML4, Hsap\PVALB, Hsap\OCM, Hsap\CABP1, Hsap\TNNC1, Hsap\EFCAB6, Hsap\OCM2, Hsap\CALML3, Hsap\CABP4, Hsap\CALB2, Hsap\CALML6, Hsap\EFCAB13, Hsap\EFCAB2, Hsap\SCGN" larval stage--adult stage organism

adult stage indirect flight muscle

FBgn0027453 Dnz1 DNZDHHC/NEW1 zinc finger protein 11 http://flybase.org/reports/FBgn0027453 - protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 lateral inhibition ; GO:0046331 | inferred from mutant phenotype protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "DNZ1, CG6627, Dnz1" "IPR001594:Palmitoyltransferase, DHHC domain" CG6627 11-Aug-17 DroID_v2017_08 "Drer\zdhhc23b, Drer\zdhhc9, Drer\zdhhc23a, Drer\zdhhc18a, Drer\zgc:77880, Drer\zdhhc12a, Drer\zdhhc5a, Drer\zdhhc22, Drer\zdhhc7, Drer\zdhhc21, Drer\zdhhc24, Drer\zdhhc12b, Drer\zdhhc1, Drer\zdhhc3b, Drer\zdhhc8b, Drer\LOC100334198, Drer\zdhhc5b, Drer\zdhhc3a, Drer\zdhhc14" "Scer\ERF2, Scer\PFA3, Scer\PFA5, Scer\SWF1" "Cele\dhhc-3, Cele\dhhc-7" "Xtro\zdhhc7, Xtro\zdhhc1, Xtro\zdhhc21, Xtro\zdhhc14, Xtro\zdhhc9, Xtro\zdhhc3, Xtro\dnz1, Xtro\zdhhc8, Xtro\zdhhc12, Xtro\zdhhc24" "Mmus\Zdhhc23, Mmus\Zdhhc8, Mmus\Zdhhc25, Mmus\Zdhhc22, Mmus\Zdhhc19, Mmus\Zdhhc5, Mmus\Zdhhc18, Mmus\Zdhhc14, Mmus\Zdhhc11, Mmus\Zdhhc1, Mmus\Zdhhc24, Mmus\Zdhhc9, Mmus\Zdhhc7, Mmus\Zdhhc3, Mmus\Zdhhc12, Mmus\Zdhhc21" "Hsap\ZDHHC19, Hsap\ZDHHC18, Hsap\ZDHHC5, Hsap\ZDHHC22, Hsap\ZDHHC9, Hsap\ZDHHC1, Hsap\ZDHHC12, Hsap\ZDHHC11, Hsap\ZDHHC23, Hsap\ZDHHC3, Hsap\ZDHHC8, Hsap\ZDHHC14, Hsap\ZDHHC7, Hsap\ZDHHC21, Hsap\ZDHHC24" " embryonic stage | syncytial blastoderm , embryonic stage -- adult stage " "viable,visible" chaeta FBgn0001105 Gbeta13F G protein beta-subunit 13F http://flybase.org/reports/FBgn0001105 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of gastrulation ; GO:0010470 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype apical protein localization ; GO:0045176 | traceable author statement cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype convergent extension involved in gastrulation ; GO:0060027 | inferred from mutant phenotype mesectoderm development ; GO:0048383 | inferred from mutant phenotype establishment or maintenance of cytoskeleton polarity involved in gastrulation ; GO:0003380 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay regulation of myosin II filament organization ; GO:0043519 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay heterotrimeric G-protein complex ; GO:0005834 | inferred from direct assay "Gbeta13F, Gbeta, G b13F, G[[beta]], G-beta, Gb13F, Gbb, clone 1.22, dgbeta, anon-EST:Liang-1.22, G-betab, CG10545, G[[beta13F]], gbeta13F, GNB1/2/3/4 like" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001632:G-protein, beta subunit, IPR001680:WD40 repeat, IPR016346:Guanine nucleotide-binding protein, beta subunit, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like" CG10545 11-Aug-17 DroID_v2017_08 "Drer\gnb1b, Drer\gnb5a, Drer\gnb2, Drer\gnb4a, Drer\gnb3a, Drer\gnb4b, Drer\gnb3b, Drer\gnb5b, Drer\gnb1a" Scer\STE4 "Cele\gpb-2, Cele\gpb-1" "Xtro\gnb3, Xtro\gnb1, Xtro\gnb4, Xtro\gnb5" "Mmus\Gnb4, Mmus\Gnb1, Mmus\Gnb3, Mmus\Gnb2" "Hsap\GNB2, Hsap\GNB3, Hsap\GNB5, Hsap\GNB1, Hsap\GNB4" " embryonic stage | mid-late , embryonic stage , embryonic stage -- adult stage , adult stage , embryonic stage | early , larval stage--adult stage , pupal stage " " organism

, embryonic central nervous system

, adult brain cortex

, thoracico-abdominal ganglion

, brain

, ovary

" adult stage " thoracico-abdominal ganglion

, neuropil

, adult brain cortex

" "wild-type,lethal,recessive,neuroanatomy defective,germline clone,visible,body color defective,partially lethal - majority die,some die during pupal stage" "spindle & neuroblast,embryonic neuroblast,neuroblast,germline clone,EL neuron,gastrula embryo,embryonic/first instar larval cuticle,anterior,posterior,embryonic neuroblast & spindle | germ-line clone,trichogen cell,mesothoracic tergum" DRSC20247 E 0.78995358 0.624084762 2.563277403 0.712443637 0.050868296 -0.056970294 FBgn0011638 La La autoantigen-like http://flybase.org/reports/FBgn0011638 FBgn0043798 protein_coding_gene 5S rRNA primary transcript binding ; GO:0008098 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | non-traceable author statement RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR002344 intracellular ribonucleoprotein complex ; GO:0030529 | inferred from electronic annotation with InterPro:IPR002344 nucleus ; GO:0005634 | inferred from direct assay euchromatin ; GO:0000791 | inferred from direct assay "CG10922, D-La, 38C.38, DLa/SS-B, dmLa, BEST:LD24519, La" "IPR000504:RNA recognition motif domain, IPR002344:Lupus La protein, IPR006630:RNA-binding protein Lupus La, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR014886:La protein, RNA-binding domain" CG10922 11-Aug-17 DroID_v2017_08 "Drer\larp7, Drer\ssb" "Scer\SLF1, Scer\LHP1, Scer\SRO9" Cele\C44E4.4 "Xtro\larp7, Xtro\ssb" "Mmus\Larp7, Mmus\Ssb" "Hsap\LARP7, Hsap\SSB" " oogenesis stage , embryonic stage -- adult stage , adult stage && oogenesis stage , embryonic stage | stage 13-16 , embryonic stage | stage 13-15 , embryonic stage | stage 17 , embryonic stage | stage >7 , embryonic stage | early , adult stage && oogenesis stage | stage , nurse cell

, visceral mesoderm

, gonad

, embryonic/larval salivary gland

, mesoderm

,

ubiquitous , follicle cell

" "lethal,recessive,viable,visible" "midgut constriction,midgut constriction 1,midgut constriction 2,midgut constriction 3,embryonic/larval midgut,trichogen cell" FBgn0005427 ewg erect wing http://flybase.org/reports/FBgn0005427 "FBgn0000609, FBgn0001600" protein_coding_gene DNA binding ; GO:0003677 | non-traceable author statement negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype imaginal disc morphogenesis ; GO:0007560 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with Apc nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement "EWG, EG:BACR37P7.7, CG3114, l(1)1Ag, l(1)DA659, EC3, l[EC3], l(1)EC3, NRF-1, l(1)VA720, l(1)EC3f, ewg, Ewg" "IPR019525:Nuclear respiratory factor 1, NLS/DNA-binding, dimerisation domain, IPR019526:Nuclear respiratory factor-1, activation binding domain" CG3114 11-Aug-17 DroID_v2017_08 Drer\nrf1 - Cele\W06A11.4 Xtro\nrf1 Mmus\Nrf1 Hsap\NRF1 embryonic stage " supraesophageal ganglion

, embryonic central nervous system

" " pupal stage | stage P4-7 , embryonic stage , embryonic stage -- adult stage , pupal stage | 10-36hr , embryonic stage && larval stage , pupal stage | 12-36hr " " adult muscle precursor primordium

, neuron

, embryonic central nervous system

, adult myoblast

, dorsal medial muscle | precursor

, coxal tergal remotor muscle | precursor

, mesothoracic extracoxal depressor muscle 66 | precursor

, embryonic peripheral nervous system

, lateral oblique dorsal muscle | precursor

, tergosternal muscle | precursor

" "neuroanatomy defective,RU486 conditional,lethal - all die before end of pupal stage,some die during pupal stage,lethal,some die during first instar larval stage,some die during embryonic stage,wild-type,viable,reduced,lethal - all die before end of embryonic stage,recessive,locomotor behavior defective,somatic clone,flightless,visible,body color defective" "NMJ bouton,RU486 conditional,embryonic/larval neuromuscular junction,synapse | third instar larval stage, with ewg2,indirect flight muscle,dorsal medial muscle,lateral oblique dorsal muscle,somatic clone,synapse | third instar larval stage, with ewg‘îDJ.elav.TIvirHA1,TVSVG,wing,mesothoracic tergum" FBgn0085424 nub nubbin http://flybase.org/reports/FBgn0085424 protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of antibacterial peptide biosynthetic process ; GO:0002809 | inferred from mutant phenotype pattern specification process ; GO:0007389 | non-traceable author statement wing disc development ; GO:0035220 | inferred from genetic interaction with Bx heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype ganglion mother cell fate determination ; GO:0007402 | traceable author statement limb joint morphogenesis ; GO:0036022 | inferred from mutant phenotype ventral cord development ; GO:0007419 | non-traceable author statement - "Pdm, pdm1, nub, CG34395, CG15489, CG15488, CG6246, dOct1, dPOU-19, dPOU19, pdm-1, twn, POU33F1, dPOU-19/pdm-1, Oct-1, pdm, Pdm-1, Pdm1, nb, PDM1, Nub, Oct1, Nb, PDM-1, NUB" "IPR017970:Homeobox, conserved site, IPR000327:POU-specific domain, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR010982:Lambda repressor-like, DNA-binding domain, IPR013847:POU domain" CG34395 11-Aug-17 DroID_v2017_08 "Drer\pou5f3, Drer\pou6f1, Drer\pou3f2b, Drer\pou3f3a, Drer\pou3f1, Drer\pou1f1, Drer\pou2f1b, Drer\pou3f3b, Drer\pou3f2a, Drer\pou2f1a, Drer\pou2f3, Drer\pou2f2a" - "Cele\ceh-18, Cele\ceh-6" "Xtro\pou6f2, Xtro\pou2f3, Xtro\pou2f1, Xtro\pou3f3, Xtro\pou1f1, Xtro\pou6f1, Xtro\pou5f3.1, Xtro\pou5f3.2, Xtro\pou3f4, Xtro\pou3f1" "Mmus\Pou6f2, Mmus\Pou2f3, Mmus\Pou2f1, Mmus\Pou3f3, Mmus\Pou3f4, Mmus\Pou2f2, Mmus\Pou3f1, Mmus\Pou3f2, Mmus\Pou5f2, Mmus\Pou6f1, Mmus\Pou5f1, Mmus\Ccdc160, Mmus\Pou1f1" "Hsap\POU6F2, Hsap\POU3F1, Hsap\POU1F1, Hsap\POU5F2, Hsap\POU2F2, Hsap\POU3F4, Hsap\CCDC160, Hsap\POU3F3, Hsap\POU3F2, Hsap\POU2F3, Hsap\POU5F1B, Hsap\POU6F1, Hsap\POU2F1, Hsap\POU5F1" " embryonic stage | 0-6 hr , larval stage | third instar , embryonic stage | stage16 , larval stage , embryonic stage | cellular blastoderm , embryonic stage | late , embryonic stage | stage 9 , embryonic stage , larval stage--adult stage , embryonic stage | mid , pupal stage , embryonic stage | mid-late , embryonic stage | stage12 , larval stage | second instar , embryonic stage | >=6 hr , larval stage&&pupal stage , embryonic stage | 0-12 hr , embryonic stage | stage 6 " " abdominal basiconical sensillum dbd

, dorsal mesothoracic disc

,

30-50% egg length , bipolar dendrite neuron dorsal thoracic cluster thoracic segment 2..3

{ + BX-C- } , hypophysis

,

segment polarity ,

51-70% egg length{ $ ftz* } , dendritic arborising neuron dorsal abdominal cluster abdominal segment 1..7

{ + BX-C- } , ectoderm | stripes

, embryonic peripheral nervous system | restricted

, embryonic/larval hypopharynx

,

segment polarity{ + BX-C- } , dorsal thoracic bd1

, larval labral segment sense organ

, peripheral nervous system abdominal segment 8..9

{ 0 AS-C{-} } , embryonic/larval pharynx

, parasegment 7

, scolopidial ligament cell lateral abdominal cluster abdominal segment 1..7

{ 0 AS-C{-} } , scolopidial ligament cell &&of dorsal thoracic cluster &&of metathoracic segment && scolopidial ligament cell &&of dorsal thoracic cluster &&of mesothoracic segment

, labral segment

, larval labral segment sense organ | precursor

, scolopidial ligament cell lateral abdominal cluster abdominal segment 1..7

{ + hb* } , neurogenic region

, ventral thoracic disc

, multidendritic sensory organ precursor cell

, optic lobe

, abdominal dorsal multidendritic neuron

, bipolar dendrite neuron dorsal abdominal cluster abdominal segment 1..7

{ + BX-C- } , central nervous system | restricted

,

18-24% egg length{ + hb* } , scolopidial ligament cell lateral abdominal cluster abdominal segment 1..7

{ - abd-A{D24} } , parasegment 11

, dorsal metathoracic disc

, abdominal 1--7 dorsal bipolar neuron dbp

, chordotonal organ &&of lateral thoracic cluster &&of prothoracic segment

, scolopidial ligament cell lateral thoracic cluster thoracic segment 2..3

{ + BX-C- } , abdominal neuroblast &&of abdominal segment 1--7

,

odd pair-rule , larval brain

, scolopidial ligament cell &&of lateral abdominal cluster &&of abdominal segment 1--7

" " embryonic stage | stage 9-11 , larval stage | third instar , embryonic stage | stage 11 , pupal stage , embryonic stage | stage 17 " " deuterocerebral neuroblast | subset

, protocerebral neuroblast | subset

, procephalic neurogenic region | restricted

, dorsal mesothoracic disc

, ganglion mother cell GMC4-2a

, ventral thoracic disc | proximal

, leg & joint | proximal & subset

, EW2 neuron

, tritocerebral neuroblast | subset

" FBgn0003515 st scarlet http://flybase.org/reports/FBgn0003515 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 synaptic vesicle amine transmembrane transporter activity ; GO:0005430 | inferred from mutant phenotype ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000443108" eye pigment precursor transport ; GO:0006856 | traceable author statement aminergic neurotransmitter loading into synaptic vesicle ; GO:0015842 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CG4314, st" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR005284:Pigment precursor permease, IPR013525:ABC-2 type transporter, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4314 11-Aug-17 DroID_v2017_08 "Drer\abcg1, Drer\abcg8, Drer\abcg4a, Drer\abcg5, Drer\abcg2a, Drer\abcg2b, Drer\abcg4b" "Scer\PDR5, Scer\PDR15, Scer\PDR10, Scer\SNQ2, Scer\PDR18, Scer\ADP1, Scer\YOL075C" "Cele\wht-4, Cele\wht-1, Cele\wht-5, Cele\wht-7, Cele\wht-6, Cele\abch-1, Cele\wht-8, Cele\wht-2, Cele\wht-3" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg3, Mmus\Abcg5, Mmus\Abcg8, Mmus\Abcg4, Mmus\Abcg2, Mmus\Abcg1" "Hsap\ABCG5, Hsap\ABCG1, Hsap\ABCG4, Hsap\ABCG8" " larval stage | third instar , embryonic stage -- adult stage "

{ 0 w1 } "eye color defective,visible,recessive,lethal,sterile,viable,heat sensitive" "pigment cell,heat sensitive" FBgn0032252 loh lonely heart http://flybase.org/reports/FBgn0032252 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR010294 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR013273 positive regulation of extracellular matrix assembly ; GO:1901203 | inferred from mutant phenotype larval heart development ; GO:0007508 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR013273 extracellular matrix ; GO:0031012 | inferred from direct assay "CT19510, CG6232, loh, Loh" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR010294:ADAM-TS Spacer 1, IPR010909:PLAC, IPR013273:Peptidase M12B, ADAM-TS" CG6232 11-Aug-17 DroID_v2017_08 "Drer\paplnb, Drer\adamtsl7, Drer\adamtsl2" - - Xtro\adamtsl4 "Mmus\Adamtsl2, Mmus\Adamtsl4, Mmus\Thsd4" "Hsap\ADAMTSL4, Hsap\ADAMTSL2, Hsap\THSD4" "lethal - all die before end of larval stage,viable,fertile,cell shape defective,short lived" "embryonic/larval heart,embryonic/larval pericardial cell,embryonic/larval heart | third instar larval stage,embryonic/larval pericardial cell | third instar larval stage,embryonic/larval alary muscle,embryonic/larval cardial cell" DRSC02943 K 0.136715505 0.690312826 -0.154288594 0.154037273 0.255737514 -1.820321281 FBgn0040898 CG14809 - http://flybase.org/reports/FBgn0040898 protein_coding_gene - - - CG14809 - - 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC25685 K -0.651109117 -0.504180537 -0.583297218 0.671164714 -1.675093808 0.04020331 FBgn0035464 PIG-B Phosphatidylinositol glycan anchor biosynthesis class B http://flybase.org/reports/FBgn0035464 protein_coding_gene mannosyltransferase activity ; GO:0000030 | inferred from sequence or structural similarity with UniProtKB:Q92521 mannosyltransferase activity ; GO:0000030 | inferred from biological aspect of ancestor with PANTHER:PTN000509188 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000509293 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with UniProtKB:Q92521 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with UniProtKB:Q92521 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000509293 "PIG-B, CG12006" IPR005599:GPI mannosyltransferase CG12006 11-Aug-17 DroID_v2017_08 Drer\pigb Scer\GPI10 "Cele\T27F7.4, Cele\eif-1" Xtro\pigb Mmus\Pigb Hsap\PIGB viable DRSC08216 I 0.311660652 1.511696428 -0.307452358 0.018435606 -0.206458354 -0.323639497 FBgn0031327 CG5397 - http://flybase.org/reports/FBgn0031327 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT16527, CG5397" "IPR002018:Carboxylesterase, type B, IPR029058:Alpha/Beta hydrolase fold" CG5397 11-Aug-17 DroID_v2017_08 "Drer\ces2, Drer\nlgn2a, Drer\nlgn2b, Drer\nlgn3b, Drer\nlgn3a, Drer\nlgn4b, Drer\cell, Drer\si:ch211-93f2.1, Drer\cel.1, Drer\nlgn1, Drer\nlgn4a, Drer\ces3" - "Cele\B0238.7, Cele\ges-1, Cele\K07C11.4, Cele\T28C12.5, Cele\W02B12.4, Cele\T28C12.4, Cele\T07H6.1" "Xtro\ces3, Xtro\nlgn2, Xtro\ces2, Xtro\LOC100494782, Xtro\cel, Xtro\nlgn4x, Xtro\nlgn3" "Mmus\Ces2e, Mmus\Ces5a, Mmus\Ces1b, Mmus\Ces2b, Mmus\Nlgn1, Mmus\Cel, Mmus\Ces2c, Mmus\Nlgn2, Mmus\Nlgn3, Mmus\Ces2h, Mmus\Ces2f, Mmus\Ces1d, Mmus\Ces1e, Mmus\Ces1f, Mmus\Ces3a, Mmus\Ces2a, Mmus\Ces1h, Mmus\Ces3b, Mmus\Ces1c, Mmus\Ces2g, Mmus\Ces4a, Mmus\Ces1g" "Hsap\CES2, Hsap\CES1, Hsap\NLGN1, Hsap\NLGN3, Hsap\CES3, Hsap\NLGN2, Hsap\NLGN4X, Hsap\CES5A, Hsap\CEL, Hsap\NLGN4Y, Hsap\CES4A" "viable,visible" mesothoracic tergum DRSC00683 I 1.72657172 -0.153607341 0.16635239 -0.076695907 1.08571374 -0.600846735 FBgn0034387 Cyp12b2 Cyp12b2 http://flybase.org/reports/FBgn0034387 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "12b2, CG15077, Cyp12b2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG15077 11-Aug-17 DroID_v2017_08 "Drer\cyp27c1, Drer\cyp27a1.2, Drer\cyp24a1, Drer\cyp27a7, Drer\cyp27b1, Drer\si:dkey-91i10.3, Drer\cyp27a1.4, Drer\zgc:136333, Drer\si:ch211-113j14.1, Drer\cyp11c1, Drer\cyp11a2" Scer\DIT2 "Cele\cyp-44A1, Cele\cyp-13A1" "Xtro\LOC100496967, Xtro\cyp27a1, Xtro\cyp27b1, Xtro\cyp24a1, Xtro\cyp27c1, Xtro\LOC100145331, Xtro\cyp11a1" "Mmus\Cyp27a1, Mmus\Cyp27b1, Mmus\Cyp24a1, Mmus\Cyp11b2, Mmus\Cyp11b1, Mmus\Cyp11a1" "Hsap\CYP11B2, Hsap\CYP27C1, Hsap\CYP24A1, Hsap\CYP27B1, Hsap\CYP27A1, Hsap\CYP11A1, Hsap\CYP11B1" viable DRSC07364 E 0.871501056 0.281365673 -1.952569604 0.397099886 -0.161412626 -0.131167278 FBgn0051283 CG31283 - http://flybase.org/reports/FBgn0051283 protein_coding_gene - - - CG31283 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC21585 E 1.246891355 0.208849481 1.320645566 1.50327091 -0.344426186 -0.508844394 FBgn0029979 mahe maheshvara http://flybase.org/reports/FBgn0029979 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD:S000005056 "RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with dx inferred from genetic interaction with N positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN001168930" - "DmRH1, cg10777, CG10777, mahe" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG10777 11-Aug-17 DroID_v2017_08 "Drer\clk2a, Drer\clk4b, Drer\clk2b, Drer\tdrd12, Drer\ddx5, Drer\ddx21, Drer\ddx59, Drer\clk4a, Drer\LOC556764" "Scer\DBP3, Scer\DBP2" "Cele\ddx-17, Cele\Y54G11A.3, Cele\madd-3" "Xtro\gpr149, Xtro\ddx21, Xtro\clk3, Xtro\ddx59, Xtro\ddx17, Xtro\clk1, Xtro\clk2, Xtro\ddx5" "Mmus\Tdrd12, Mmus\Ddx17, Mmus\Ddx50, Mmus\Ddx3x, Mmus\Ddx21, Mmus\Clk4, Mmus\Ddx5, Mmus\Clk3, Mmus\Ddx59, Mmus\Clk2, Mmus\Gpr149, Mmus\Clk1" "Hsap\CLK1, Hsap\CLK3, Hsap\DDX17, Hsap\GPR149, Hsap\DDX5, Hsap\CLK4, Hsap\CLK2, Hsap\DDX59, Hsap\TDRD12, Hsap\DDX43, Hsap\DDX21, Hsap\DDX50" "lethal,recessive,viable" DRSC17755 E 0.050851615 -0.604360319 -1.581805473 0.389549804 0.422833257 0.343642908 FBgn0040601 CG13643 - http://flybase.org/reports/FBgn0040601 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG13642, CG13643" IPR002557:Chitin binding domain CG13643 11-Aug-17 DroID_v2017_08 - - Cele\Y56A3A.6 - - - viable DRSC14642 K 0.137652897 0.004362843 0.592541484 0.1342383 0.137261914 -1.745520698 FBgn0037106 CG11307 - http://flybase.org/reports/FBgn0037106 protein_coding_gene - - - CG11307 IPR031813:Domain of unknown function DUF4745 CG11307 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC11648 E -0.58017616 -0.124858497 -0.642693669 -2.86790718 -0.283064192 0.119311417 FBgn0022069 Nnp-1 Nnp-1 http://flybase.org/reports/FBgn0022069 FBgn0032508 protein_coding_gene - rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000314942 "preribosome, small subunit precursor ; GO:0030688 | inferred from electronic annotation with InterPro:IPR010301 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000314942 preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000314942" "Nnp1, nnp-1, l(2)k07826, CG12396, Nnp-1, NNP-1" "IPR010301:Nucleolar, Nop52" CG12396 11-Aug-17 DroID_v2017_08 Drer\rrp1 Scer\RRP1 Cele\C47E12.7 Xtro\rrp1b "Mmus\Rrp1b, Mmus\Rrp1" "Hsap\RRP1, Hsap\RRP1B" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" DRSC02165 IE -1.851885995 0.298341706 2.167803045 -0.631249859 -0.49803586 0.001420522 FBgn0030790 CG4768 - http://flybase.org/reports/FBgn0030790 protein_coding_gene - - - CG4768 IPR029196:Protein of unknown function DUF4588 CG4768 11-Aug-17 DroID_v2017_08 "Drer\zgc:77849, Drer\zgc:66160" - Cele\C48B6.3 Xtro\c16orf72 Mmus\1810013L24Rik Hsap\C16orf72 viable DRSC19917 E 0.365765951 -0.117165246 1.90078 1.249010401 -0.349664918 -0.773762213 FBgn0000422 Ddc Dopa decarboxylase http://flybase.org/reports/FBgn0000422 FBgn0022245 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 aromatic-L-amino-acid decarboxylase activity ; GO:0004058 | traceable author statement aromatic-L-amino-acid decarboxylase activity ; GO:0004058 | inferred from direct assay inferred from mutant phenotype cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010977 thermosensory behavior ; GO:0040040 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype thermotaxis ; GO:0043052 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from genetic interaction with Hn response to wounding ; GO:0009611 | inferred from expression pattern adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype eclosion rhythm ; GO:0008062 | non-traceable author statement developmental pigmentation ; GO:0048066 | traceable author statement regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from mutant phenotype inferred from genetic interaction with Ask1 learning or memory ; GO:0007611 | non-traceable author statement dopamine biosynthetic process from tyrosine ; GO:0006585 | inferred from mutant phenotype serotonin biosynthetic process from tryptophan ; GO:0006587 | inferred from mutant phenotype growth ; GO:0040007 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement anesthesia-resistant memory ; GO:0007615 | inferred from direct assay - "Dopa decarboxylase, DDC, CG10697, ddc, AADC, 5-HT, fDDC, DdcDm, l(2)k02104, l(2)37Ch, l(2)37Bl, Ddc" "IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR010977:Aromatic-L-amino-acid decarboxylase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase, IPR021115:Pyridoxal-phosphate binding site" CG10697 11-Aug-17 DroID_v2017_08 "Drer\ddc, Drer\hdc" - "Cele\hdl-1, Cele\bas-1, Cele\basl-1, Cele\tdc-1" "Xtro\hdc, Xtro\ddc" "Mmus\Ddc, Mmus\Hdc" "Hsap\HDC, Hsap\DDC" " larval stage | third instar--A , embryonic stage , embryonic stage | early , adult stage , oogenesis stage && adult stage | female , larval stage | third instar " " testis

, ovary

, adult thorax

, adult head

" " adult stage , larval stage , larval stage | third instar , larval stage | third instar--A , embryonic stage | stage 17 , larval stage | third instar stage 2 , adult stage | female " " adult brain | restricted

, ring gland

, adult hindgut

, larval central nervous system

, EW1 neuron

, ventral nerve cord

, epidermis

, larval ventricular ganglion

, recurrent nerve

, neuron | subset

, EW2 neuron

, thoracico-abdominal ganglion | restricted

, frontal ganglion

, glial cell | subset

, larval stomatogastric nervous system

, oviduct

, LP1 neuron

, larval brain | restricted

, larval maxillary nerve

" "lethal,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage,developmental rate defective,small body,locomotor behavior defective,lethal - all die before end of larval stage,some die during third instar larval stage,partially,visible,wild-type,wound healing defective,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,learning defective,viable,somatic clone,body color defective,lethal - all die before end of pupal stage,some die during pupal stage,flight defective,memory defective" "macrochaeta,cuticle,axillary sclerite,adult cuticle,leg,wing,embryonic/larval heart,somatic clone,microchaeta,triple row,chaeta,wing hair,embryonic/larval cuticle,pupal cuticle,adult thorax,trichogen cell,mesothoracic tergum" FBgn0011771 Hem HEM-protein http://flybase.org/reports/FBgn0011771 "FBgn0010794, FBgn0026230" protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with Abi protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:B1Q236,UniProtKB:Q8MLQ0,UniProtKB:Q9VF87,UniProtKB:Q9VKM2,UniProtKB:Q9Y0S9" actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype neuron migration ; GO:0001764 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from mutant phenotype SCAR complex ; GO:0031209 | inferred from physical interaction with SCAR plasma membrane ; GO:0005886 | inferred from direct assay SCAR complex ; GO:0031209 | inferred from direct assay "kette, Kette, dhem, kte, dhem-2, l(3)03335, CG5837, Hem, Nap1, Nap, Kette/Nap1, Hem1, HEM, dNap, dNAP" IPR019137:Nck-associated protein 1 CG5837 11-Aug-17 DroID_v2017_08 "Drer\nckap1, Drer\hsp70.2, Drer\hsp70.1, Drer\si:dkey-4p15.3, Drer\hsp70l, Drer\hsc70, Drer\hspa8, Drer\si:ch211-199o1.2, Drer\zgc:172352" - "Cele\hsp-70, Cele\gex-3, Cele\F44E5.5, Cele\F44E5.4" "Xtro\hspa1b, Xtro\hspa8, Xtro\nckap1, Xtro\hspa1a, Xtro\hspa2, Xtro\nckap1l, Xtro\hsp70, Xtro\gxylt1, Xtro\hspa1l" "Mmus\Hspa2, Mmus\Nckap1, Mmus\Hspa1b, Mmus\Hspa1a, Mmus\Hspa8, Mmus\Nckap1l, Mmus\Hspa1l" "Hsap\HSPA8, Hsap\NCKAP1, Hsap\HSPA1L, Hsap\HSPA1B, Hsap\HSPA6, Hsap\NCKAP1L, Hsap\HSPA2, Hsap\HSPA1A" " embryonic stage | stage 14 , embryonic stage | stage 13 , embryonic stage | stage 17 , embryonic stage | stage 1-6 , embryonic stage | stage 14-17 , adult stage && oogenesis stage | stage S10 , embryonic stage | stage 7-10 , embryonic stage -- adult stage " " supraesophageal ganglion

,

ubiquitous , embryonic/larval pharynx

, embryonic brain

, ventral nerve cord

, follicle cell

, procephalic neuroblast

, oocyte

" " embryonic stage , "

"neuroanatomy defective,cell migration defective,dominant,lethal,recessive,visible,cell shape defective,viable,poor,wild-type,partially lethal - majority die,some die during pupal stage" "RP2 motor neuron | embryonic stage,intersegmental nerve,axon,neuromuscular junction & synapse,microchaeta,supernumerary,macrochaeta,thecogen cell & actin filament & pupa-537.4,thecogen cell | P-stage,actin filamentb,larval neuromuscular junction & bouton,eye,filamentous actin | pupal stageGMR.PU,actin filament,embryonic/larval neuromuscular junction,adult head & macrochaeta,ventral nerve cord commissure,longitudinal connective,somatic muscle primordium,embryonic/larval somatic muscle,RP2 motor neuron,embryonic myoblast,fusion competent cell,muscle founder cell,actin cytoskeleton,muscle attachment site,S2 cell-line & filopodium | ectopic,S2 cell-line & actin filament | ectopic,lamina plexus,photoreceptor cell & axon,medulla,presumptive embryonic/larval central nervous system,commissure,midline glial cell,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron,VUM neuron,ventral midline & neuron,interface glial cell,embryonic/larval midgut,cytoskeleton,cytoskeleton & mesoderm,cytoskeleton & ectoderm,cytoskeleton & embryonic central nervous system,cytoskeleton & embryonic epidermis | dorsal,chaeta" DRSC11865 E 0.608609603 0.112115352 2.676664061 -0.744008192 -0.368223033 0.204963929 FBgn0000253 Cam Calmodulin http://flybase.org/reports/FBgn0000253 "FBgn0010559, FBgn0015611, FBgn0027677" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Crag myosin V binding ; GO:0031489 | inferred from physical interaction with didum calcium ion binding ; GO:0005509 | inferred from direct assay myosin heavy chain binding ; GO:0032036 | inferred from physical interaction with didum myosin VI head/neck binding ; GO:0070855 | inferred from physical interaction with jar rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | traceable author statement metarhodopsin inactivation ; GO:0016060 | inferred from genetic interaction with Gαq sensory perception of sound ; GO:0007605 | inferred from mutant phenotype kinetochore organization ; GO:0051383 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from direct assay regulation of light-activated channel activity ; GO:0016061 | inferred from mutant phenotype positive regulation of cation channel activity ; GO:2001259 | inferred from direct assay muscle cell cellular homeostasis ; GO:0046716 | inferred from genetic interaction with Dys lateral inhibition ; GO:0046331 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype adaptation of rhodopsin mediated signaling ; GO:0016062 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from mutant phenotype positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok actin filament-based movement ; GO:0030048 | inferred from direct assay plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay midbody ; GO:0030496 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay myosin VI complex ; GO:0031476 | inferred from physical interaction with jar mitotic spindle ; GO:0072686 | inferred from direct assay myosin V complex ; GO:0031475 | inferred from physical interaction with didum nucleoplasm ; GO:0005654 | inferred from direct assay mitotic spindle pole ; GO:0097431 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay rhabdomere ; GO:0016028 | traceable author statement rhabdomere ; GO:0016028 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CaM, CG8472, dCaM, DmCalm, cam, l(2)3909, CAM, 3909, D-CaM, anon-EST:Posey59, l(2)03909, Cal49A, Cal, Cam, Cam1, lincRNA.S2634, DmCaM, CalA" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG8472 11-Aug-17 DroID_v2017_08 "Drer\caln1, Drer\calm3b, Drer\pvalb8, Drer\tnnc1a, Drer\pvalb9, Drer\caln2, Drer\si:ch211-197n1.2, Drer\calb2b, Drer\calm1b, Drer\cabp1a, Drer\pvalb1, Drer\rhbdl3, Drer\efcab6, Drer\cabp5a, Drer\calm1a, Drer\efcab2, Drer\efcab11, Drer\cabp2a, Drer\cabp5b, Drer\calb2a, Drer\pvalb3, Drer\calm2b, Drer\pvalb6, Drer\cabp7b, Drer\pvalb2, Drer\calm3a, Drer\tnnc2, Drer\cabp1b, Drer\calml4a, Drer\calb1, Drer\calm2a, Drer\calml4b, Drer\pvalb4, Drer\cabp2b, Drer\cabp4, Drer\tnnc1b, Drer\scgn" "Scer\MLC1, Scer\CMD1, Scer\MLC2" "Cele\cal-4, Cele\cmd-1, Cele\tnc-2, Cele\cal-3, Cele\cal-2, Cele\cal-1" "Xtro\pgm1, Xtro\scgn, Xtro\cabp7, Xtro\calb1, Xtro\cabp4, Xtro\calml4, Xtro\pvalb.2, Xtro\LOC548651, Xtro\tnnc2, Xtro\ocm.2, Xtro\tnnc1, Xtro\pvalb.1, Xtro\efcab6, Xtro\calm1, Xtro\calm2, Xtro\ocm, Xtro\pvalb" "Mmus\Cabp7, Mmus\Cabp4, Mmus\Calml3, Mmus\Rhbdl3, Mmus\Caln1, Mmus\Cabp5, Mmus\Spata21, Mmus\Calml4, Mmus\Efcab6, Mmus\Calm5, Mmus\Calm1, Mmus\Efcab11, Mmus\Cabp2, Mmus\Tnnc2, Mmus\Tnnc1, Mmus\Calb2, Mmus\Efcab9, Mmus\Calm3, Mmus\Efcab2, Mmus\Calb1, Mmus\Pvalb, Mmus\Ocm, Mmus\Efcab7, Mmus\Calm2, Mmus\1700023F06Rik, Mmus\Calm4, Mmus\Efcab3, Mmus\Scgn, Mmus\Cabp1" "Hsap\CALB2, Hsap\TNNC1, Hsap\PVALB, Hsap\CABP7, Hsap\EFCAB11, Hsap\CALML4, Hsap\OCM2, Hsap\CALM1, Hsap\CABP2, Hsap\CALN1, Hsap\EFCAB13, Hsap\SCGN, Hsap\CALM3, Hsap\CALB1, Hsap\EFCAB2, Hsap\CALM2, Hsap\CABP5, Hsap\CABP4, Hsap\CABP1, Hsap\SPATA21, Hsap\OCM, Hsap\CALML3, Hsap\EFCAB7, Hsap\C2orf61, Hsap\EFCAB9, Hsap\EFCAB6, Hsap\CALML5, Hsap\CALML6, Hsap\RHBDL3, Hsap\TNNC2, Hsap\EFCAB3" " adult stage , embryonic stage | mid-late , embryonic stage | mid , embryonic stage | late " " adult head

, embryonic central nervous system | presumptive

, posterior embryonic/larval midgut

, anterior embryonic/larval midgut

, peripheral nervous system

" "lethal,viable,recessive,locomotor behavior defective,wild-type,behavior defective,visual behavior defective,lethal - all die before end of larval stage,some die during larval stage,hypoactive,neurophysiology defective,lethal - all die before end of pupal stage,some die during pupal stage,auditory perception defective,lethal - all die before end of P-stage,some die during pharate adult stage,mating defective,flightless,flight defective,uncoordinated,neuroanatomy defective,visible" "wing vein,ectopic,mesothoracic tergum,photoreceptor,ommatidium,pupa,adult head,pupal cuticle,longitudinal muscle,bouton & abdominal 2 ventral longitudinal muscle 2,bouton & abdominal 3 ventral longitudinal muscle 2,bouton & abdominal 4 ventral longitudinal muscle 2,bouton & abdominal 5 ventral longitudinal muscle 2,bouton & abdominal 6 ventral longitudinal muscle 2,bouton & abdominal 7 ventral longitudinal muscle 2,chaeta" FBgn0087040 alphaTub67C alpha-Tubulin at 67C http://flybase.org/reports/FBgn0087040 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002452, InterPro:IPR008280, InterPro:IPR017975 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002452 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity" central nervous system development ; GO:0007417 | inferred from mutant phenotype sperm aster formation ; GO:0035044 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity mRNA transport ; GO:0051028 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype female pronucleus assembly ; GO:0035038 | inferred from mutant phenotype embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype embryonic cleavage ; GO:0040016 | inferred from mutant phenotype pronuclear migration ; GO:0035046 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype nuclear division ; GO:0000280 | inferred from mutant phenotype perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cortical microtubule ; GO:0055028 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay microtubule ; GO:0005874 | inferred from sequence or structural similarity "alphaTub67C, alphaTub 67C, alpha-Tub, alpha-Tub67C, alpha-tub67C, alpha-tubulin, alpha4, alpha4-t, alpha4t, alpha67C, alphaTUB, alphaTub, Fs(3)Kav, alpha-tubulin[4], Fs(3)Kavar, Fs(3)Sz14, CG8308, ALPHA 67C, D.m.ALPHA-67C, aTub67C, alpha4Tub67C, Tom, T, 4t, Fs(3)Tomaj, DTA2, Fs(3)Tom, Fs(3)Sz22, Tub, alphaTub4, alphaTub[67C], alphatub, alphatub67C, mum-tub67C, Kavar, alpha4-tubulin, tub, tub67c, alpha-tub, gamma-Tub, Tub1E, tubulin" "IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain, IPR000217:Tubulin, IPR002452:Alpha tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal" CG8308 11-Aug-17 DroID_v2017_08 "Drer\tuba8l3, Drer\tuba8l, Drer\tuba8l2, Drer\tuba1b, Drer\tuba7l, Drer\tuba1c, Drer\tuba1a, Drer\si:ch211-114n24.6, Drer\tuba4l, Drer\tuba8l4, Drer\tuba2, Drer\si:ch73-199e17.1" "Scer\TUB3, Scer\TUB1" "Cele\tba-5, Cele\tba-7, Cele\tba-8, Cele\tba-1, Cele\tba-6, Cele\mec-12, Cele\tba-9, Cele\tba-4, Cele\tba-2" "Xtro\tuba8, Xtro\tuba1c, Xtro\tuba3c, Xtro\tuba4, Xtro\tuba4a, Xtro\tuba1a, Xtro\tuba4b, Xtro\tubal3, Xtro\tuba3e" "Mmus\Tubal3, Mmus\Tuba3b, Mmus\Tuba1b, Mmus\Tuba8, Mmus\Tuba1a, Mmus\Tuba4a, Mmus\Tuba1c, Mmus\Tuba3a" "Hsap\TUBA3C, Hsap\TUBA3E, Hsap\TUBA4A, Hsap\TUBAL3, Hsap\TUBA1C, Hsap\TUBA1B, Hsap\TUBA8, Hsap\TUBA3D, Hsap\TUBA1A" " adult stage && oogenesis stage | stage >=S10B , adult stage , embryonic stage | 0-2 hr , adult stage && oogenesis stage | stage <=S10B , adult stage && oogenesis stage , larval stage , embryonic stage | 0-12 hr , embryonic stage | stage 1-4 , embryonic stage | early , pupal stage , adult stage && oogenesis stage | stage >=S1 " " oocyte

, nurse cell

, ovary

, egg chamber

" " embryonic stage | early , embryonic stage | stage 13 , embryonic stage , adult stage && oogenesis stage , embryonic stage | 10 hr , egg stage | unfertilized egg " " longitudinal connective

, ovary

, ventral nerve cord commissure

, ventral midline

, unfertilized egg

, embryonic central nervous system

" DRSC11321 IE 2.115505178 -1.773754176 3.463222012 -1.082995485 -0.30730508 -0.549388021 FBgn0013753 Bgb Big brother http://flybase.org/reports/FBgn0013753 - protein_coding_gene transcription factor binding ; GO:0008134 | traceable author statement protein heterodimerization activity ; GO:0046982 | traceable author statement transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity with HGNC:10472 inferred from direct assay inferred from physical interaction with run regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "bgb, en(lz)D/9, rpbeta2, CG7959, Bgb" "IPR003417:Core binding factor, beta subunit" CG7959 11-Aug-17 DroID_v2017_08 Drer\cbfb - Cele\bro-1 Xtro\cbfb Mmus\Cbfb Hsap\CBFB " embryonic stage , embryonic stage | stage >=13 " "

ubiquitous , embryonic central nervous system

" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" abdominal vch1 neuron FBgn0004863 C15 C15 http://flybase.org/reports/FBgn0004863 "FBgn0002943, FBgn0008640, FBgn0010393" protein_coding_gene sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from physical interaction with al "chaeta development ; GO:0022416 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype elongation of arista core ; GO:0035015 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay positive regulation of Notch signaling pathway ; GO:0045747 | inferred from expression pattern antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype mesodermal cell fate specification ; GO:0007501 | non-traceable author statement leg disc development ; GO:0035218 | inferred from mutant phenotype" protein complex ; GO:0043234 | inferred from physical interaction with al "C15, cll, Cll, Ect5, 311, Hox11-311, CG7937, 93Bal, c15" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR020479:Homeobox domain, metazoa" CG7937 11-Aug-17 DroID_v2017_08 "Drer\vox, Drer\barhl1b, Drer\dbx1b, Drer\lbx1a, Drer\tlx1, Drer\hmx2, Drer\lbx2, Drer\nkx1.2lb, Drer\hlx1, Drer\barhl2, Drer\hmx1, Drer\pnx, Drer\tlx2, Drer\hmx4, Drer\hmx3b, Drer\LOC100008066, Drer\tlx3b, Drer\barx2, Drer\lbx1b, Drer\barx1, Drer\ved" Scer\HMRA1 "Cele\mls-2, Cele\lim-7, Cele\ceh-51, Cele\pha-2" "Xtro\pdx1, Xtro\barhl1, Xtro\nkx1-1, Xtro\nkx1-2, Xtro\hhex, Xtro\barhl2, Xtro\tlx2, Xtro\barx1, Xtro\ventx1.2, Xtro\nkx3-1, Xtro\tlx1, Xtro\dbx1, Xtro\hmx3, Xtro\tlx3, Xtro\hmx1, Xtro\hmx2, Xtro\hlx" "Mmus\Barhl2, Mmus\Tlx3, Mmus\Tlx2, Mmus\Hmx1, Mmus\Hlx, Mmus\Barhl1, Mmus\Dbx2, Mmus\Hmx2, Mmus\Dbx1, Mmus\Nkx3-1, Mmus\Barx1, Mmus\Tlx1, Mmus\Nkx1-1, Mmus\Hhex, Mmus\Lbx1, Mmus\Nkx1-2, Mmus\Barx2, Mmus\Lbx2, Mmus\Hmx3" "Hsap\NKX1-1, Hsap\HMX2, Hsap\TLX1, Hsap\TLX3, Hsap\HLX, Hsap\BARHL2, Hsap\DBX2, Hsap\DBX1, Hsap\TLX2, Hsap\BARX1, Hsap\LBX2, Hsap\BARX2, Hsap\LBX1, Hsap\HMX3, Hsap\BARHL1, Hsap\NKX3-1, Hsap\HHEX" " larval stage | late , pupal stage | early , embryonic stage | cellular blastoderm , embryonic stage | 4-24hr " dorsal ectoderm anlage | restricted

"lethal,some die during immature adult stage,recessive,partially,viable" "arista,unguis,tarsal segment 4,pulvillus,empodium,pretarsus,mesothoracic bristle,ocellar bristle" DRSC13495 K 1.046389853 -0.419385742 -0.579551324 0.199508799 -0.410530514 -1.878787893 FBgn0030093 Bap111 Brahma associated protein 111kD http://flybase.org/reports/FBgn0030093 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with mor transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with HGNC:11109 "ATP-dependent chromatin remodeling ; GO:0043044 | inferred from electronic annotation with InterPro:IPR030089 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from genetic interaction with brm inferred from physical interaction with brm" SWI/SNF complex ; GO:0016514 | inferred from electronic annotation with InterPro:IPR030089 nucleus ; GO:0005634 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay brahma complex ; GO:0035060 | inferred from physical interaction with brm PBAF complex ; GO:0070604 | inferred from direct assay "dalao, BAP111, BAF57, CG7055, Bap111, clone 1.83, anon-EST:Liang-1.83, BAP 111, Dalao" "IPR009071:High mobility group box domain, IPR030089:SWI/SNF complex subunit BAF57" CG7055 11-Aug-17 DroID_v2017_08 Drer\smarce1 "Scer\RUD3, Scer\NHP6B, Scer\NHP6A" Cele\swsn-3 Xtro\smarce1 Mmus\Smarce1 Hsap\SMARCE1 "viable,fertile,lethal,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" DRSC18419 E -1.202774072 -0.115092816 -1.580244651 0.943217708 0.5414767 -0.9141211 FBgn0038627 CG7694 - http://flybase.org/reports/FBgn0038627 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:28037 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein autoubiquitination ; GO:0051865 | inferred from sequence or structural similarity with HGNC:28037 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 - "BcDNA:LP11469, CG7694" "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG7694 11-Aug-17 DroID_v2017_08 "Drer\rnf32, Drer\znrf3, Drer\si:dkey-51a16.9, Drer\si:ch1073-392o20.1, Drer\rnf11a, Drer\rnf115, Drer\zswim2, Drer\rnf126, Drer\rnf24, Drer\rnf130, Drer\si:ch211-81a5.1, Drer\rnf44, Drer\rnf150, Drer\rnf11b, Drer\pja2, Drer\rnf165a, Drer\rnf6, Drer\rnf181, Drer\zgc:175214, Drer\rnf150a, Drer\rnf38, Drer\wu:fb39e10, Drer\rnf215, Drer\rlim, Drer\rnf165b, Drer\rnf111, Drer\rnf13, Drer\rnf103" "Scer\YBR062C, Scer\SAN1, Scer\ASR1" "Cele\K12B6.8, Cele\C18B12.4, Cele\F19B10.10, Cele\toe-4" "Xtro\rnf11.2, Xtro\rnf32, Xtro\chmp3, Xtro\rnf38, Xtro\rnf11, Xtro\rlim, Xtro\znrf3, Xtro\rnf24, Xtro\rnf44, Xtro\pja2, Xtro\rnf181, Xtro\rnf111, Xtro\rnf149, Xtro\rnf126, Xtro\rnf115" "Mmus\Zswim2, Mmus\Rnf11, Mmus\Rnf130, Mmus\Rnf32, Mmus\Znrf3, Mmus\Rnf122, Mmus\4930595M18Rik, Mmus\Rnf38, Mmus\Pja2, Mmus\Rnf126, Mmus\Pja1, Mmus\Rnf165, Mmus\Rlim, Mmus\Rnf111, Mmus\Rnf149, Mmus\Rnf6, Mmus\Rnf43, Mmus\Rnf103, Mmus\Rnf24, Mmus\Rnf150, Mmus\Rnf44, Mmus\Rnf115, Mmus\Rnf181, Mmus\Rnf13, Mmus\Rnf215" "Hsap\RNF13, Hsap\RNF115, Hsap\PJA2, Hsap\RNF44, Hsap\RLIM, Hsap\RNF11, Hsap\RNF6, Hsap\RNF165, Hsap\RNF126, Hsap\RNF43, Hsap\ZNRF3, Hsap\RNF111, Hsap\RNF24, Hsap\RNF149, Hsap\RNF150, Hsap\PJA1, Hsap\RNF215, Hsap\RNF103, Hsap\RNF122, Hsap\RNF38, Hsap\RNF130, Hsap\RNF181, Hsap\ZSWIM2, Hsap\RNF32, Hsap\CHMP3" "viable,fertile" DRSC16288 E -0.103254096 -0.489509088 -1.570453504 0.248034514 0.483892792 0.983302956 FBgn0030584 CG14407 - http://flybase.org/reports/FBgn0030584 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR002109 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR002109 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR002109 - "BcDNA:RH03087, CG14407, Grx5" "IPR002109:Glutaredoxin, IPR004480:Monothiol glutaredoxin-related, IPR012336:Thioredoxin-like fold, IPR033658:Glutaredoxin, PICOT-like" CG14407 11-Aug-17 DroID_v2017_08 "Drer\glrx3, Drer\glrx5" "Scer\GRX3, Scer\GRX4, Scer\GRX5" "Cele\F47B8.4, Cele\glrx-5, Cele\glrx-3, Cele\F47B8.3" "Xtro\glrx3, Xtro\glrx5" "Mmus\Glrx5, Mmus\Glrx3" "Hsap\GLRX5, Hsap\GLRX3" "viable,visible" tormogen cell DRSC19593 K 0.426901158 1.084434679 0.389040598 -0.033652491 -0.270485987 1.618495604 FBgn0011556 zetaTry zetaTrypsin http://flybase.org/reports/FBgn0011556 - protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP110, DmZetaTry, zetaTry, CG12387" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG12387 11-Aug-17 DroID_v2017_08 "Drer\zmp:0000001088, Drer\si:ch211-165b19.8" - Cele\try-1 Xtro\try10 "Mmus\Egfbp2, Mmus\Hpn, Mmus\Prss53, Mmus\Prss36, Mmus\Prss55" "Hsap\PRSS53, Hsap\HPN, Hsap\PRSS36, Hsap\PRSS48" viable DRSC07720 K -0.669007 0.609929679 -0.293252833 -0.014790772 1.998710348 1.848528767 FBgn0039613 CG14527 - http://flybase.org/reports/FBgn0039613 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG14527 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR030082:Neprilysin-21" CG14527 11-Aug-17 DroID_v2017_08 "Drer\ece2b, Drer\phex, Drer\ece1, Drer\mmel1" - "Cele\nep-26, Cele\nep-12, Cele\nep-24, Cele\nep-5, Cele\nep-16, Cele\nep-7, Cele\nep-3, Cele\nep-19, Cele\nep-8, Cele\nep-10, Cele\nep-23, Cele\nep-17, Cele\nep-6, Cele\nep-21, Cele\nep-20, Cele\nep-18, Cele\nep-9, Cele\nep-13" "Xtro\ece1, Xtro\ecel1, Xtro\ece2, Xtro\mmel1" "Mmus\Mme, Mmus\Ece2, Mmus\Ecel1, Mmus\Phex, Mmus\Ece1, Mmus\Kel, Mmus\Mmel1" "Hsap\KEL, Hsap\ECE2, Hsap\MMEL1, Hsap\MME, Hsap\ECE1, Hsap\ECEL1, Hsap\PHEX" DRSC14878 K -0.264941403 0.004509544 -0.453878995 0.657443327 -0.247967355 1.709492447 FBgn0002773 Mlc2 Myosin light chain 2 http://flybase.org/reports/FBgn0002773 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 myofibril assembly ; GO:0030239 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype muscle system process ; GO:0003012 | inferred from mutant phenotype myofibril ; GO:0030016 | inferred from mutant phenotype myosin complex ; GO:0016459 | inferred from sequence or structural similarity "MRLC, RLC, mlc-2, DmMLC2, RLC2, CG2184, Dmlc2, MYL2, mlc2, Ifm(3)99Eb, LC2, MLC-2, dro MLC-2, MLC2, l(3)99Eb, Mlc2, MLC, MLC 2, Dmlc, dMLC-2, myosin, RLC1" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG2184 11-Aug-17 DroID_v2017_08 "Drer\myl12.2, Drer\mylpfa, Drer\mylpfb, Drer\myl2b, Drer\myl12.1, Drer\myl7, Drer\myl9a, Drer\myl2a, Drer\myl10, Drer\myl9b" Scer\MLC2 "Cele\mlc-4, Cele\mlc-1, Cele\mlc-2" "Xtro\myl9, Xtro\myl10, Xtro\myl7, Xtro\myl2, Xtro\mylpf, Xtro\myl12b" "Mmus\Myl2, Mmus\Myl10, Mmus\Myl7, Mmus\Myl12a, Mmus\Myl9, Mmus\Mylpf, Mmus\Myl12b" "Hsap\MYL9, Hsap\MYLPF, Hsap\MYL2, Hsap\MYL7, Hsap\MYL12B, Hsap\MYL12A, Hsap\MYL5, Hsap\MYL10" "wild-type,viable,flightless,female fertile,male fertile,flight defective,dominant,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "sarcomere, with Mlc2E38,indirect flight muscle & myofibril,indirect flight muscle & striated muscle thick filament,indirect flight muscle & striated muscle thin filament,indirect flight muscle & Z disc,sarcomere,sarcomere, with Mlc2S66A,S67A,sarcomere, with Mlc2‘î2-46" DRSC28878 K 0.096548434 -0.255454365 0.451642371 0.449442111 0.092077847 1.592682391 FBgn0032639 CG18563 - http://flybase.org/reports/FBgn0032639 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "SPH156, CG18563" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG18563 11-Aug-17 DroID_v2017_08 "Drer\tmprss9, Drer\zmp:0000001114, Drer\zgc:55888, Drer\st14a" - - - "Mmus\Tmprss13, Mmus\St14, Mmus\Gzma, Mmus\Gzmm" "Hsap\TMPRSS13, Hsap\GZMA, Hsap\ST14, Hsap\GZMM" viable DRSC02676 E -0.400086816 -0.199980305 2.17651789 -0.151481979 -0.56555944 0.481865279 FBgn0003866 tsh teashirt http://flybase.org/reports/FBgn0003866 "FBgn0000058, FBgn0010570, FBgn0013543" protein_coding_gene "transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P18824 DNA binding ; GO:0003677 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000281113" "Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype inferred from physical interaction with UniProtKB:P18824 leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype Malpighian tubule stellate cell differentiation ; GO:0061330 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype specification of segmental identity, trunk ; GO:0035292 | inferred from mutant phenotype negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype epidermis morphogenesis ; GO:0048730 | inferred from mutant phenotype wing disc proximal/distal pattern formation ; GO:0007473 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | traceable author statement specification of segmental identity, thorax ; GO:0007384 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype Malpighian tubule stellate cell differentiation ; GO:0061330 | inferred from expression pattern regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype salivary gland development ; GO:0007431 | non-traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "tsh, T shirt, ae[l], ae, l(2)B4-2-12, l(2)04319, CG1374, Tsh" "IPR013087:Zinc finger C2H2-type, IPR026807:Protein tiptop/teashirt, IPR027008:Teashirt family" CG1374 11-Aug-17 DroID_v2017_08 "Drer\tshz3a, Drer\tshz1" - - "Xtro\tshz3, Xtro\tshz2" "Mmus\Tshz2, Mmus\Tshz1, Mmus\Tshz3" "Hsap\TSHZ1, Hsap\TSHZ3, Hsap\TSHZ2" " embryonic stage , embryonic stage | stage 13 , embryonic stage | extended germ band , embryonic stage | embryonic cycle 14A , embryonic stage | contracted germ band stage , embryonic stage | blastoderm " " epidermis &&of parasegment 3--13

, head

{ + Ubxhs.P } ,

{ v Antp* } , prothoracic segment | posterior

{ - Scr*, BX-C- } , somatic mesoderm

, mesothoracic segment

, metathoracic segment | posterior

{ - Scr*, BX-C- } , embryonic/larval pharynx

, parasegment 6

{ ^ BX-C- } , labial segment

{ + Antphs.PHTA } , head

,

{ 0 Dfd* } ,

45-60% egg length , abdominal segment 1--8

, embryonic central nervous system

, midgut constriction 2

, visceral mesoderm

, abdominal segment 1..8 | posterior

{ + salm* } , larval anus

, mesothoracic segment | posterior

{ - Scr*, BX-C- } ,

{ 0 lab* } , parasegment 6..13

{ - Scr*, BX-C- } , parasegment 2..13 embryonic central nervous system

{ 0 Scr* } , parasegment 4,5

{ ^ Ubx* } , parasegment 3--13

, parasegment 2,14,15

{ + salm* } " " embryonic stage | stage 15 , larval stage | third instar , embryonic stage | stage 8 , larval stage | second instar " " embryonic Malpighian tubule | restricted

, dorsal mesothoracic disc

, parasegment 3--14

" "visible,recessive,viable,lethal,mitotic cell cycle defective,dominant,heat sensitive,homeotic,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,flightless,some die during pupal stage,partially lethal,short lived,planar polarity defective,segment polarity phenotype,large body,developmental rate defective,lethal - all die before end of pupal stage,cell shape defective" "eye,ectopic,antennal disc,somatic clone,ventral,wing hinge,wing sclerite,haltere sclerite,vertical cleft,wing,haltere,leg,trochanter,coxa,femur,prothoracic coxal sensillum trichodeum,mesothoracic coxal sensillum trichodeum,metathoracic coxal sensillum trichodeum,prothoracic coxal bristle on hairy island,mesothoracic coxal bristle on hairy island,anterior scutellar bristle,Keilin's organ,mitotic cell cycle,wing vein,wing margin,maxillary palpus,adult head,arista,head & eye | ectopic,antenna & eye | ectopic,procephalic segment,heat sensitive,maxillary segment,labial segment,denticle belt,midgut constriction 1,midgut constriction 2,prothoracic segment,embryonic/larval cuticle,denticle row 1,denticle row 2,denticle row 3,denticle row 4,embryonic/first instar larval cuticle,embryonic prothoracic segment,embryonic labial segment,dorsal,larval abdomen,larval thorax,larval mesothoracic segment,larval abdominal segment 1,denticle row 5,supernumerary,proximal,metaphase & condensed nuclear chromosome,mitotic anaphase,mitotic metaphase,adult Malpighian tubule,adult abdomen,adult Malpighian tubule Type II cell,mouthpart,denticle belt & embryonic prothoracic segment,abdomen,eye-antennal disc,wing disc,eye disc,photoreceptor cell,antenna,denticle,embryonic head,T1 beard,embryonic maxillary segment,embryonic antennal segment,larval labial segment,larval maxillary segment & denticle | ectopic69B,larval antennal segment & denticle | ectopic69B,dorsal closure embryo,larval head,leg & cuticle | ventral | somatic clone,leg & cuticle | dorsal | somatic clone,leg & cuticle | somatic clone,tibia,prothoracic femoral bract,mesothoracic femoral bract,metathoracic femoral bract,ventral thoracic disc,leg & cuticle | ventral | somatic clonearm.THsimVP16,leg & cuticle | dorsal | somatic clonearm.THsimVP16,leg & cuticle | somatic clonearm.THsimVP16,cuprophilic cell,interommatidial bristle,eye photoreceptor cell,ectopic | third instar larval stage,dorsal compartment" FBgn0004828 His3.3B Histone H3.3B http://flybase.org/reports/FBgn0004828 "FBgn0025266, FBtr0071345, FBpp0071280, FBtr0071346, FBpp0071281, FBtr0071347, FBpp0071282" protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000164, InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072" male meiosis ; GO:0007140 | inferred from genetic interaction with His3.3A nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR000164 "H3.3, His3.3, H3.3B, PH3, anon-EST:fe1B6, HisH3-3Q, CG8989, His3.3B, His 3.3B, dH3.3B" "IPR000164:Histone H3/CENP-A, IPR007125:Histone H2A/H2B/H3, IPR009072:Histone-fold" CG8989 11-Aug-17 DroID_v2017_08 "Drer\LOC108190747, Drer\si:ch73-36p18.2, Drer\h3f3a, Drer\zgc:113984, Drer\zgc:173552, Drer\hist2h3c, Drer\LOC108190746, Drer\zgc:113983, Drer\h3f3c, Drer\hist2h3ca1, Drer\si:ch1073-429i10.3, Drer\cenpa, Drer\h3f3b.1, Drer\h3f3d" "Scer\HHT2, Scer\HHT1, Scer\CSE4" "Cele\his-9, Cele\his-13, Cele\his-17, Cele\his-55, Cele\his-2, Cele\his-71, Cele\his-59, Cele\his-69, Cele\his-70, Cele\his-74, Cele\his-32, Cele\his-42, Cele\his-72, Cele\his-27, Cele\his-45, Cele\his-49, Cele\his-63, Cele\his-6, Cele\his-25" "Xtro\h3f3b, Xtro\h3f3a, Xtro\h3f3b, Xtro\hist2h3d, Xtro\cenpa" "Mmus\Hist1h3e, Mmus\Hist1h3i, Mmus\H3f3a, Mmus\Hist1h3f, Mmus\Hist1h3c, Mmus\Hist1h3g, Mmus\Hist1h3b, Mmus\Cenpa, Mmus\H3f3c, Mmus\H3f3b, Mmus\Hist1h3a, Mmus\Hist2h3c2, Mmus\Hist1h3h, Mmus\Hist2h3b, Mmus\Hist2h3c1, Mmus\Hist1h3d" "Hsap\H3F3B, Hsap\HIST2H3D, Hsap\HIST1H3B, Hsap\H3F3C, Hsap\HIST1H3J, Hsap\CENPA, Hsap\HIST2H3A, Hsap\HIST1H3G, Hsap\HIST3H3, Hsap\HIST1H3E, Hsap\HIST1H3I, Hsap\HIST2H3C, Hsap\HIST1H3D, Hsap\HIST1H3A, Hsap\HIST1H3C, Hsap\H3F3A, Hsap\HIST1H3F, Hsap\HIST1H3H" " adult stage | female , oogenesis stage && adult stage | female , embryonic stage , spermatogenesis && adult stage , adult stage | male " " ovary

, testis

" " spermatogenesis && adult stage , larval stage " " spermatid

, larval salivary gland

, Y chromosome loop

, spermatocyte

, protein body

" viable DRSC18673 I -0.584147781 -2.117266808 -0.734575842 -0.450716052 0.147359308 0.055199479 FBgn0029094 asf1 anti-silencing factor 1 http://flybase.org/reports/FBgn0029094 protein_coding_gene RNA polymerase II repressing transcription factor binding ; GO:0001103 | inferred from physical interaction with H protein binding ; GO:0005515 | inferred from physical interaction with Tlk protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P02299 inferred from physical interaction with UniProtKB:P84040 protein binding ; GO:0005515 | inferred from physical interaction with Bx42 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24572 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P25439 inferred from physical interaction with UniProtKB:Q9VF03 "nucleosome assembly ; GO:0006334 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from direct assay regulation of mRNA splicing, via spliceosome ; GO:0048024 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from genetic interaction with Tlk muscle organ development ; GO:0007517 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype" polytene chromosome ; GO:0005700 | inferred from direct assay CAF-1 complex ; GO:0033186 | colocalizes_with inferred from direct assay transcriptional repressor complex ; GO:0017053 | colocalizes_with inferred from direct assay RCAF complex ; GO:0035059 | inferred from direct assay "ASF1, dASF/SF2, Asf1, dASF1, CG9383, asf1, dAsf1, l(3)76BDq" IPR006818:Histone chaperone ASF1-like CG9383 11-Aug-17 DroID_v2017_08 "Drer\asf1ba, Drer\asf1bb" Scer\ASF1 "Cele\unc-85, Cele\asfl-1" "Xtro\asf1b, Xtro\asf1a" "Mmus\Asf1a, Mmus\Asf1b" "Hsap\ASF1A, Hsap\ASF1B" embryonic stage -- adult stage "lethal,recessive,suppressor of variegation,dominant,lethal - all die before end of larval stage,some die during larval stage,female sterile,germline clone,visible,heat sensitive,viable" "ovary,germline clone,eye,larval salivary gland & nucleushs.2sev,macrochaeta,embryonic/larval salivary gland,trichogen cell" DRSC24067 IK 0.760593263 -2.154179605 -0.053583318 -0.77273666 -1.54696121 -0.745990721 FBgn0002941 slou slouch http://flybase.org/reports/FBgn0002941 FBgn0004442 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype mesodermal cell fate specification ; GO:0007501 | non-traceable author statement muscle organ development ; GO:0007517 | traceable author statement muscle cell fate determination ; GO:0007521 | inferred from expression pattern nucleus ; GO:0005634 | inferred from direct assay "S59, s59, slou/NK1, NK1, S-59, S59/NK-1, NK-1, NK1/S59, Nk1, prd9, CG6534, slou, Slou" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG6534 11-Aug-17 DroID_v2017_08 "Drer\barhl2, Drer\ved, Drer\gbx2, Drer\tlx2, Drer\barhl1b, Drer\lbx2, Drer\tlx1, Drer\barx2, Drer\nkx1.2la, Drer\hlx1, Drer\lbx1b, Drer\LOC100008066, Drer\lbx1a, Drer\vox, Drer\pou2f3, Drer\gbx1, Drer\barx1, Drer\nkx1.2lb, Drer\tlx3b, Drer\dbx1b, Drer\pnx, Drer\pou5f3" - "Cele\ceh-1, Cele\ceh-16" "Xtro\barhl1, Xtro\tlx2, Xtro\gbx2.2, Xtro\dbx1, Xtro\barhl2, Xtro\ventx1.2, Xtro\nkx1-1, Xtro\tlx1, Xtro\barx1, Xtro\nkx1-2, Xtro\hlx, Xtro\tlx3, Xtro\gbx2.1" "Mmus\Nkx1-2, Mmus\Lbx1, Mmus\Gbx2, Mmus\Barx1, Mmus\Nkx1-1, Mmus\Barhl2, Mmus\Lbx2, Mmus\Dbx1, Mmus\Barx2, Mmus\Tlx1, Mmus\Tlx2, Mmus\Tlx3, Mmus\Hlx, Mmus\Meox1, Mmus\Gbx1, Mmus\Meox2, Mmus\Barhl1, Mmus\Dbx2" "Hsap\DBX2, Hsap\MEOX1, Hsap\BARHL1, Hsap\LBX1, Hsap\GBX2, Hsap\GBX1, Hsap\TLX2, Hsap\TLX3, Hsap\BARX1, Hsap\BARHL2, Hsap\LBX2, Hsap\NKX1-1, Hsap\HLX, Hsap\DBX1, Hsap\BARX2, Hsap\TLX1, Hsap\MEOX2, Hsap\NKX1-2" embryonic stage | early embryonic stage " ganglion mother cell

, abdominal 2--7 ventral transverse muscle 1

, abdominal 1 ventral acute muscle 2

, abdominal 1 dorsal transverse muscle 1

, somatic mesoderm | restricted

, larval muscle system | restricted

, supraesophageal ganglion | restricted

, embryonic/larval midgut | restricted

, embryonic central nervous system

, abdominal 2--7 dorsal transverse muscle 1

, abdominal 2--7 ventral acute muscle 2

" "lethal,recessive,flight defective,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" "presumptive embryonic/larval muscle system,abdominal 2 ventral transverse muscle 1,abdominal 3 ventral transverse muscle 1,abdominal 4 ventral transverse muscle 1,abdominal 5 ventral transverse muscle 1,abdominal 6 ventral transverse muscle 1,abdominal 7 ventral transverse muscle 1,abdominal 2 dorsal transverse muscle 1,abdominal 3 dorsal transverse muscle 1,abdominal 4 dorsal transverse muscle 1,abdominal 5 dorsal transverse muscle 1,abdominal 6 dorsal transverse muscle 1,abdominal 7 dorsal transverse muscle 1,A2-7 ventral transverse muscle 1,A1-7 ventral acute muscle 3,A1-7 ventral acute muscle 1,A1-7 ventral acute muscle 2,A1-7 lateral oblique muscle 1,segment border muscle,A1-7 dorsal oblique muscle 3,A1-7 dorsal transverse muscle 1,embryonic/larval somatic muscle,ventral,abdominal lateral adult muscle precursor cell,abdominal ventral adult muscle precursor cell,wing,cardioblast,adult muscle precursor cell,embryonic/larval dorsal vessel" FBgn0011701 repo reversed polarity http://flybase.org/reports/FBgn0011701 "FBgn0010814, FBgn0013744, FBgn0051240" protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 nervous system development ; GO:0007399 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype glial cell differentiation ; GO:0010001 | non-traceable author statement regulation of phagocytosis ; GO:0050764 | inferred from mutant phenotype inferred from genetic interaction with drpr inferred from genetic interaction with NimC4 positive regulation of gene expression ; GO:0010628 | inferred from direct assay glial cell development ; GO:0021782 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "repo, Repo, RK2, CG8045(CT24072), CT24072, REPO, rk2, 3702, l(3)03702, CG31240, AbRK2" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG31240 11-Aug-17 DroID_v2017_08 "Drer\lhx6, Drer\lhx8a, Drer\pax6a, Drer\rx1, Drer\alx1, Drer\otx5, Drer\hoxb8a, Drer\pax6b, Drer\phox2a, Drer\alx3, Drer\mxtx2, Drer\pdlim3b, Drer\pitx3, Drer\alx4a, Drer\pdlim7, Drer\shox, Drer\gsc, Drer\dmbx1b, Drer\arxa, Drer\rx2, Drer\shox2, Drer\pitx1, Drer\ldb3a, Drer\dmbx1a" "Scer\YHP1, Scer\PXL1, Scer\PHO2" "Cele\alp-1, Cele\ceh-10, Cele\ceh-45, Cele\lim-4, Cele\vab-3, Cele\ceh-51" "Xtro\hoxb8, Xtro\pdlim5, Xtro\arx, Xtro\lhx8, Xtro\pax3, Xtro\alx1, Xtro\shox2, Xtro\alx4, Xtro\gsc, Xtro\pitx1, Xtro\pitx3" "Mmus\Arx, Mmus\Alx4, Mmus\Gsc, Mmus\Lhx2, Mmus\Alx3, Mmus\Pdlim1, Mmus\Pdlim5, Mmus\Pax6, Mmus\Pdlim7, Mmus\Pdlim3, Mmus\Pitx1, Mmus\Isx, Mmus\Pax3, Mmus\Lhx6, Mmus\Lhx8, Mmus\Ldb3, Mmus\Pitx3, Mmus\Dmbx1, Mmus\Shox2, Mmus\Gsc2" "Hsap\SHOX, Hsap\ALX1, Hsap\PAX4, Hsap\ALX4, Hsap\GSC2, Hsap\HOXB8, Hsap\PDLIM1, Hsap\LHX8, Hsap\PAX3, Hsap\ISX, Hsap\DMBX1, Hsap\LPXN, Hsap\GSC, Hsap\ARX, Hsap\SHOX2, Hsap\PDLIM7, Hsap\PITX1, Hsap\PDLIM3, Hsap\LHX6, Hsap\PITX3, Hsap\LDB3, Hsap\ALX3, Hsap\LHX2, Hsap\PAX6" " embryonic stage , embryonic stage | stage 9 " " glial cell

, glioblast

, interface glial cell

" " embryonic stage , larval stage | third instar , embryonic stage | stage 10-11 , embryonic stage | stage 9-11 " " bipolar dendrite neuron

, peripheral glial cell 1--3

, medial intersegmental nerve root glial cell

, larval optic stalk

, channel glial cell

, tritocerebrum && CNS glial cell | subset

, glial cell &&of central nervous system

, glial cell &&of ventral thoracic disc

, glial cell &&of eye-antennal disc

, peripheral glial cell

, embryonic peripheral nervous system

, support cell of the dorsal bipolar dendritic cell

, tritocerebral neuroblast | subset

, exit glial cell

, scolopidial ligament cell

, B subperineurial glial cell of abdomen

, glial cell &&of dorsal mesothoracic disc

, lateral intersegmental nerve root glial cell

, medial-most cell body glial cell

, protocerebrum && CNS glial cell | subset

, A subperineurial glial cell

, interface glial cell

, intersegmental nerve root glial cell

" "viable,neurophysiology defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "lamina anlage,lamina & neuron,lamina & glial cell,retina,retina & axon,ventral nerve cord,VUM1 neuron & axon,VUM2 neuron & axon,VUM3 neuron & axon,VUM4 neuron & axon,VUM5 neuron & axon,VUM6 neuron & axon,glial cell,medial-most cell body glial cell,embryonic/larval glial cell,intersegmental nerve branch ISNb of A1-7,longitudinal connective,interface glial cell,lateral cord glial cell,PNS glial cell,trichogen cell,mesothoracic tergum" FBgn0004870 bab1 bric a brac 1 http://flybase.org/reports/FBgn0004870 "FBgn0035183, FBgn0061802" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement AT DNA binding ; GO:0003680 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with bip2" "adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype female sex differentiation ; GO:0046660 | traceable author statement sex differentiation ; GO:0007548 | traceable author statement eye-antennal disc morphogenesis ; GO:0007455 | inferred from expression pattern transcription, DNA-templated ; GO:0006351 | traceable author statement sex-specific pigmentation ; GO:0048071 | traceable author statement regulation of developmental pigmentation ; GO:0048070 | traceable author statement negative regulation of male pigmentation ; GO:0048092 | non-traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 sex differentiation ; GO:0007548 | inferred from mutant phenotype inferred from genetic interaction with abd-A inferred from genetic interaction with Abd-B negative regulation of developmental pigmentation ; GO:0048086 | traceable author statement leg disc morphogenesis ; GO:0007478 | inferred from expression pattern regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "bab1, bab, BAB1, bab-I, CG13910, CG9097, anon-WO0118547.639, BAB-1, Bab1, BAB, bric-a-brac" "IPR000210:BTB/POZ domain, IPR007889:DNA binding HTH domain, Psq-type, IPR011333:SKP1/BTB/POZ domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR009057:Homeobox domain-like" CG9097 11-Aug-17 DroID_v2017_08 - - "Cele\sdz-28, Cele\btb-13" - - "Hsap\NACC1, Hsap\NACC2" " larval stage | third instar stage 2 , larval stage | third instar , prepupal stage " " ventral thoracic disc | restricted

, ventral thoracic disc | restricted

, ovary | restricted

, eye-antennal disc | restricted

" " prepupal stage | stage P1 , prepupal stage , larval stage | third instar , larval stage | third instar stage 2 " " ovary | restricted

, tarsal segment

, eye-antennal disc | restricted

, central nervous system | restricted

, male genital disc | restricted

, larval central nervous system | restricted

, ventral thoracic disc | restricted

, female genital disc | restricted

" "female sterile,recessive,visible,partially,body color defective,female,dominant,heat sensitive,partially lethal - majority die,lethal,lethal - all die before end of pupal stage,some die during pupal stage" "metathoracic tarsal segment 2,metathoracic tarsal segment 3,metathoracic tarsal segment 4,metathoracic tarsal segment 5,sex comb,ectopic,basal cylinder,ovary,terminal filament,germarium,ovariole,abdominal tergite 6,female,abdominal tergite 7,abdominal tergite 5,leg,antenna,prothoracic tarsal segment 2,prothoracic tarsal segment 3,prothoracic tarsal segment 4,prothoracic tarsal segment 5,mesothoracic tarsal segment 2,mesothoracic tarsal segment 3,mesothoracic tarsal segment 4,mesothoracic tarsal segment 5,macrochaeta,tergite" FBgn0000084 AnxB10 Annexin B10 http://flybase.org/reports/FBgn0000084 - protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001464, InterPro:IPR018252, InterPro:IPR018502 calcium-dependent phospholipid binding ; GO:0005544 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity" biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred by curator from GO:0005544 "CG9579, Annx, anxX, Ann, annexin, AnxB10, ANXB10, AnnX" "IPR018252:Annexin repeat, conserved site, IPR018502:Annexin repeat, IPR001464:Annexin" CG9579 11-Aug-17 DroID_v2017_08 "Drer\anxa5a, Drer\zgc:110283, Drer\anxa3b, Drer\anxa2a, Drer\anxa1c, Drer\anxa11a, Drer\anxa5b, Drer\anxa4, Drer\zgc:101785, Drer\anxa2b, Drer\anxa13l, Drer\anxa11b, Drer\anxa13, Drer\anxa1a, Drer\anxa3a, Drer\anxa1b, Drer\anxa6" - "Cele\nex-1, Cele\nex-3, Cele\nex-2" "Xtro\anxa5, Xtro\anxa11, Xtro\anxa2, Xtro\anxa3, Xtro\anxa6, Xtro\anxa13, Xtro\anxa4, Xtro\anxa8, Xtro\anxa1, Xtro\anxa7" "Mmus\Anxa6, Mmus\Anxa2, Mmus\Anxa9, Mmus\Anxa8, Mmus\Anxa7, Mmus\Anxa11, Mmus\Anxa4, Mmus\Anxa3, Mmus\Anxa1, Mmus\Anxa5, Mmus\Anxa10, Mmus\Anxa13" "Hsap\ANXA4, Hsap\ANXA8L1, Hsap\ANXA2, Hsap\ANXA3, Hsap\ANXA9, Hsap\ANXA10, Hsap\ANXA5, Hsap\ANXA7, Hsap\ANXA8, Hsap\ANXA6, Hsap\ANXA11, Hsap\ANXA1, Hsap\ANXA13" " embryonic stage , adult stage " "viable,fertile" DRSC25182 K -0.285198964 0.143723332 1.375469101 0.511433235 -1.626364031 -0.749220534 FBgn0000541 E(bx) Enhancer of bithorax http://flybase.org/reports/FBgn0000541 "FBgn0013553, FBgn0016686, FBgn0035116, FBgn0035117, FBgn0035118, FBgn0061199" protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 lysine-acetylated histone binding ; GO:0070577 | inferred from direct assay nucleosome-dependent ATPase activity ; GO:0070615 | contributes_to inferred by curator from GO:0016589 ligand-dependent nuclear receptor binding ; GO:0016922 | inferred from physical interaction with EcR methylated histone binding ; GO:0035064 | inferred from direct assay "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from direct assay ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from genetic interaction with EcR nucleosome mobilization ; GO:0042766 | inferred from direct assay dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype inferred from genetic interaction with N mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs chromatin organization ; GO:0006325 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype nucleosome mobilization ; GO:0042766 | traceable author statement negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype hemopoiesis ; GO:0030097 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype" NURF complex ; GO:0016589 | traceable author statement NURF complex ; GO:0016589 | inferred from direct assay "NURF301, NURF, Nurf301, CG32346, CG17135, E(Bx), nurf301, NURF215, p215, NURF-301, p301, CG10894, dNURF, l(3)122, NURF-215, Nurf-215, l(3)ry122, En-bx, CG7022, CG32478, E(bx), NuRF301, dNURF301, E(BX), Nurf 301, NURF 215, Ebx, e(bx), Nurf" "IPR018359:Bromodomain, conserved site, IPR018501:DDT domain, IPR001487:Bromodomain, IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR028942:WHIM1 domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG32346 11-Aug-17 DroID_v2017_08 "Drer\bptf, Drer\cxxc1a, Drer\cxxc1b" "Scer\GCN5, Scer\SPP1" "Cele\npp-2, Cele\nurf-1" "Xtro\cxxc1, Xtro\bptf" "Mmus\Baz2a, Mmus\Dido1, Mmus\Bptf, Mmus\Cxxc1" "Hsap\CXXC1, Hsap\DIDO1, Hsap\BPTF, Hsap\BAZ2A" "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,germline clone,maternal effect,tumorigenic,viable,visible" "melanotic mass,polytene chromosomeNurf301-3),polytene chromosome,hemocyte,supernumerary,polytene chromosome3643),embryonic/larval hemocyte,dendrite,polytene chromosomeNurf301-2),embryonic/larval brain,chaeta,mesothoracic tergum" DRSC08583 IK -2.071342701 -0.359274794 -0.098412755 0.526552019 1.896558313 0.7325247 FBgn0022724 Taf8 TBP-associated factor 8 http://flybase.org/reports/FBgn0022724 FBgn0014200 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 protein binding ; GO:0005515 | inferred from physical interaction with Taf10b cellular process ; GO:0009987 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype transcription factor TFIID complex ; GO:0005669 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:17300 "dmTAF8, Prodos, TAF, pds, TFIID, TAF[[II]], TAF8, CG7128, prod, HL-VIII, pro, l(1)16Fg, Taf8" "IPR006565:Bromodomain associated domain, IPR019473:Transcription factor TFIID, subunit 8, C-terminal, IPR009072:Histone-fold" CG7128 11-Aug-17 DroID_v2017_08 "Drer\taf8, Drer\taf3, Drer\mtrf1l" "Scer\TAF3, Scer\TAF8" "Cele\phf-34, Cele\Y54E2A.8, Cele\W03F8.3, Cele\taf-8, Cele\taf-3" "Xtro\mtrf1, Xtro\taf8, Xtro\mtrf1l" "Mmus\Taf8, Mmus\Mtrf1, Mmus\Taf3, Mmus\Mtrf1l" "Hsap\TAF8, Hsap\TAF3, Hsap\MTRF1L" "viable,fertile,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,cell lethalcell lethal,somatic clone,visible,lethal - all die before end of pupal stage,some die during pupal stage" "third instar larva,mesothoracic tergum" DRSC20363 IK -1.739406467 0.489849821 -0.642661665 -0.483991124 0.683414644 2.620180346 FBgn0038049 CG5844 - http://flybase.org/reports/FBgn0038049 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001753 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR001753 phagocytosis ; GO:0006909 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype - CG5844 "IPR001753:Crotonase superfamily, IPR029045:ClpP/crotonase-like domain" CG5844 11-Aug-17 DroID_v2017_08 Drer\zgc:101569 "Scer\DCI1, Scer\ECI1" "Cele\C32E8.9, Cele\ech-3" "Xtro\LOC100135367, Xtro\LOC100488770" Mmus\Echdc1 Hsap\ECHDC1 "visible,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing vein" DRSC15890 IEK -3.414130964 -4.647446683 -1.713021855 -6.921746308 -1.917433292 -0.541825762 FBgn0040078 pont pontin http://flybase.org/reports/FBgn0040078 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR010339 ATP-dependent 5'-3' DNA helicase activity ; GO:0043141 | inferred from electronic annotation with InterPro:IPR027238 transcription coactivator activity ; GO:0003713 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V3K3 inferred from physical interaction with UniProtKB:Q9W4S7 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone exchange ; GO:0043486 | inferred from direct assay regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred by curator from GO:0031011 mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from direct assay mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs nucleus ; GO:0005634 | inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay Ino80 complex ; GO:0031011 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay "Pontin, Tip49/Pontin, dPontin, CG4003, dPon, Tip49, pon, dpon, 0229/05, l(3)S022905, anon-WO0118547.698, pont, Pont, PONT, RUVBL1, PON, dRUVBL1, pontin" "IPR003593:AAA+ ATPase domain, IPR010339:TIP49, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027238:RuvB-like" CG4003 11-Aug-17 DroID_v2017_08 "Drer\ruvbl2, Drer\sccpdha, Drer\zgc:174379, Drer\ruvbl1, Drer\sccpdhb" Scer\RVB1 "Cele\ruvb-1, Cele\ruvb-2, Cele\ldp-1" "Xtro\ruvbl2, Xtro\LOC100490002, Xtro\ruvbl1" "Mmus\Ruvbl2, Mmus\Ruvbl1, Mmus\Sccpdh" "Hsap\RUVBL2, Hsap\SCCPDH, Hsap\RUVBL1" "lethal,recessive,developmental rate defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,visible" "wing,somatic clone" DRSC17029 IEK -2.690886924 -0.008929931 -0.774996728 -2.013769098 0.18591314 1.665425273 FBgn0039959 CG17514 - http://flybase.org/reports/FBgn0039959 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from electronic annotation with InterPro:IPR033173 protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR033173 ribosome binding ; GO:0043022 | inferred from electronic annotation with InterPro:IPR033173 regulation of translation ; GO:0006417 | inferred from electronic annotation with InterPro:IPR033173 positive regulation of kinase activity ; GO:0033674 | inferred from electronic annotation with InterPro:IPR033173 cellular response to stress ; GO:0033554 | inferred from electronic annotation with InterPro:IPR033173 - CG17514 "IPR011989:Armadillo-like helical, IPR021133:HEAT, type 2, IPR000357:HEAT repeat, IPR016024:Armadillo-type fold, IPR034085:TOG domain, IPR033173:Translational activator Gcn1" CG17514 11-Aug-17 DroID_v2017_08 Drer\gcn1 "Scer\YEF3, Scer\NEW1, Scer\HEF3, Scer\GCN1" Cele\gcn-1 Xtro\gcn1 Mmus\Gcn1l1 Hsap\GCN1 viable DRSC20865 IE 0.709733597 -1.791643878 3.384964252 0.170475714 0.217238826 -0.301330453 FBgn0000114 bru1 bruno 1 http://flybase.org/reports/FBgn0000114 "FBgn0015367, FBgn0045095, FBgn0045436, FBgn0051762, FBgn0063197" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with apt mRNA binding ; GO:0003729 | traceable author statement mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay mRNA binding ; GO:0003729 | non-traceable author statement RNA binding ; GO:0003723 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with orb mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA 3'-UTR binding ; GO:0003730 | traceable author statement "negative regulation of translation ; GO:0017148 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from genetic interaction with enok regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype regulation of myofibril size ; GO:0014881 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of oskar mRNA translation ; GO:0007319 | non-traceable author statement negative regulation of oskar mRNA translation ; GO:0007319 | traceable author statement negative regulation of oskar mRNA translation ; GO:0007319 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of stem cell differentiation ; GO:2000738 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype positive regulation of exit from mitosis ; GO:0031536 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype" nuclear body ; GO:0016604 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from genetic interaction with sbr cytoplasm ; GO:0005737 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay "Bru, bru, bruno, arrest/Bruno, CG6319, Dm Bru, NEST:bs34h11, NEST:bs01g04, ms(2)01284, CG31762, BcDNA:GM15173, Bruno, Aret, ARET, aret/bruno1, aret, bru1" "IPR000504:RNA recognition motif domain, IPR034196:CELF1/2, RNA recognition motif 1" CG31762 11-Aug-17 DroID_v2017_08 "Drer\hug, Drer\celf1, Drer\celf5a, Drer\si:dkey-205h23.2, Drer\celf3b, Drer\celf2, Drer\celf3a, Drer\celf4" - "Cele\unc-75, Cele\etr-1" "Xtro\celf1, Xtro\celf4, Xtro\celf2, Xtro\celf3, Xtro\celf5" "Mmus\Celf5, Mmus\Celf3, Mmus\Celf6, Mmus\Celf2, Mmus\Celf4, Mmus\Celf1" "Hsap\CELF1, Hsap\CELF2, Hsap\CELF4, Hsap\CELF5, Hsap\CELF3, Hsap\CELF6" " adult stage | male , adult stage | female , oogenesis stage && adult stage | female , adult stage && oogenesis stage " " testis

, germarium region 2a

, nurse cell

, germarium

, oocyte

" adult stage && oogenesis stage " oocyte

, nurse cell

, germarium

" "semi-sterile,embryonic/larval segmentation phenotype,partially lethal - majority die,recessive,male sterile,behavior defective,visible,female sterile,lethal - all die before end of embryonic stage,dominant,maternal effect,partially,some die during embryonic stage,viable" "embryonic/larval cuticle,posterior,female germline cyst,embryo,dorsal appendage,embryonic abdominal segment,maternal effect,wing,embryonic/first instar larval cuticle,ovary,egg chamber,nurse cell,oocyte,ovariole,nurse cell fusome,nurse cell spectrosome,nurse cell ring canal,germ cell & egg chamber | supernumerary,germ cell & egg chamber,mitosis | ectopic | oogenesis stage S4,mitosis | ectopic,mitosis | oogenesis stage S4,germline clone,oogonial cell,ectopic,ring canal,chorion,micropyle,female germline stem cell,progressive,female germline stem cell | larval stage,germ cell & egg chamber | supernumeraryesc-P3-0),germ cell & egg chamberesc-P3-0)" DRSC01238 IEK -2.800126077 -6.276498211 -2.763887093 -5.981616053 0.482230002 5.447174761 FBgn0004573 5-HT7 5-hydroxytryptamine (serotonin) receptor 7 http://flybase.org/reports/FBgn0004573 - protein_coding_gene dopamine neurotransmitter receptor activity ; GO:0004952 | inferred from electronic annotation with InterPro:IPR000929 G-protein coupled serotonin receptor activity ; GO:0004993 | traceable author statement serotonin binding ; GO:0051378 | inferred from biological aspect of ancestor with PANTHER:PTN001955878 G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from sequence or structural similarity neurotransmitter receptor activity ; GO:0030594 | inferred from biological aspect of ancestor with PANTHER:PTN000664111 "adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | inferred from biological aspect of ancestor with PANTHER:PTN001955878 male courtship behavior, orientation prior to leg tapping and wing vibration ; GO:0016543 | inferred from mutant phenotype courtship behavior ; GO:0007619 | inferred from mutant phenotype serotonin receptor signaling pathway ; GO:0007210 | inferred from sequence or structural similarity adenylate cyclase-activating serotonin receptor signaling pathway ; GO:0007192 | traceable author statement male courtship behavior, proboscis-mediated licking ; GO:0016546 | inferred from mutant phenotype serotonin receptor signaling pathway ; GO:0007210 | inferred from direct assay male courtship behavior, veined wing vibration ; GO:0016545 | inferred from mutant phenotype female mating behavior ; GO:0060180 | inferred from mutant phenotype male mating behavior ; GO:0060179 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR000929 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "5HT[[7Dro]], Dm5HTdro1, 5-HT[[7]], 5HT-dro1, 5-HTdro1, 5-HT-dro, 5-HT[[7Dro]], 5-HT-dro1, DRO1, 5htdror, 5-HT[[dro1]], 5-HT7Dro, 5HT-dro, CG12073, 5HT-R1, 5-HT7, 5-HT[[7]]Dro, 5HT-7, 5-HT[7]Dro, 5HT7, HT7" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000929:Dopamine receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG12073 11-Aug-17 DroID_v2017_08 "Drer\htr1ab, Drer\htr7b, Drer\LOC100536080, Drer\htr1fb, Drer\LOC101885642, Drer\htr1aa, Drer\htr1e, Drer\htr1fa, Drer\htr1b, Drer\htr7c, Drer\htr7a, Drer\htr5aa, Drer\htr1d, Drer\LOC101884460, Drer\htr5ab, Drer\adra2a, Drer\LOC100330650" - "Cele\ser-4, Cele\ser-7, Cele\ser-2, Cele\octr-1, Cele\tyra-3" "Xtro\htr1b, Xtro\htr7, Xtro\htr1f" "Mmus\Htr1a, Mmus\Htr1d, Mmus\Htr1f, Mmus\Htr7, Mmus\Adra2a, Mmus\Htr5a, Mmus\Htr1b, Mmus\Htr5b" "Hsap\HTR1E, Hsap\HTR1B, Hsap\HTR1D, Hsap\HTR7, Hsap\HTR5A, Hsap\HTR1F, Hsap\ADRA2A, Hsap\HTR1A" " embryonic stage | stage 16-17 , adult stage " " ventral midline

, adult head

" "courtship behavior defective,mating behavior defective,viable,fertile,short lived,starvation stress response defective" Malpighian tubule FBgn0024958 Irp-1A Iron regulatory protein 1A http://flybase.org/reports/FBgn0024958 - protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR029784 iron-responsive element binding ; GO:0030350 | inferred from direct assay aconitate hydratase activity ; GO:0003994 | inferred from direct assay" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000573, InterPro:IPR001030, InterPro:IPR015931, InterPro:IPR015932, InterPro:IPR015937 response to iron(II) ion ; GO:0010040 | inferred from electronic annotation with InterPro:IPR029784 cellular iron ion homeostasis ; GO:0006879 | inferred from electronic annotation with InterPro:IPR029784 ventral furrow formation ; GO:0007370 | inferred from mutant phenotype" - "IRP-1A, IRP1, IRP-1, CG4900, Irp-1A, C-Acon, cAcon, irp1A, cACON, c-Acon, dIRP, IRP, IRF" "IPR015928:Aconitase/3-isopropylmalate dehydratase, swivel, IPR015931:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3, IPR015932:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2, IPR018136:Aconitase family, 4Fe-4S cluster binding site, IPR000573:Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, IPR001030:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain, IPR006249:Aconitase/Iron-responsive element-binding protein 2, IPR029784:Iron regulatory protein 1" CG4900 11-Aug-17 DroID_v2017_08 "Drer\ireb2, Drer\aco2, Drer\aco1" "Scer\ACO1, Scer\ACO2" "Cele\aco-1, Cele\aco-2" "Xtro\aco1, Xtro\ireb2" "Mmus\Aco1, Mmus\Ireb2, Mmus\Aco2" "Hsap\ACO2, Hsap\IREB2, Hsap\ACO1" embryonic stage

ubiquitous "lethal,viable" FBgn0036285 toe twin of eyg http://flybase.org/reports/FBgn0036285 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay compound eye development ; GO:0048749 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Toe, CG10704, anon-WO0172774.89, toe" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG10704 11-Aug-17 DroID_v2017_08 "Drer\pax7b, Drer\pax2b, Drer\pax10, Drer\pitx1, Drer\mxtx1, Drer\pax6b, Drer\alx4a, Drer\pax4, Drer\arxb, Drer\meox1, Drer\pitx3, Drer\pax1a, Drer\pax8, Drer\alx4b, Drer\hoxd11a, Drer\pax6a, Drer\arxa, Drer\pax3a, Drer\pax5, Drer\pax7a, Drer\pax2a, Drer\pax3b, Drer\prrx1a, Drer\rx3, Drer\mxtx2, Drer\pax9, Drer\pax1b, Drer\mixl1" - "Cele\eyg-1, Cele\alr-1, Cele\pax-2, Cele\pax-1, Cele\vab-3, Cele\egl-38, Cele\dsc-1" "Xtro\pitx3, Xtro\pax1, Xtro\nkx1-1, Xtro\pax2, Xtro\pax6, Xtro\sia1, Xtro\bix1.1, Xtro\pax7, Xtro\pax8, Xtro\mix1, Xtro\mixer, Xtro\pax9, Xtro\pax5, Xtro\pax3, Xtro\arx" "Mmus\Mixl1, Mmus\Rhox4b, Mmus\Rhox12, Mmus\Pax1, Mmus\Rhox7a, Mmus\Cphx3, Mmus\Rhox3f, Mmus\Rhox4e, Mmus\Pax9, Mmus\Duxbl2, Mmus\Duxbl3, Mmus\Rhox3a2, Mmus\Rhox2d, Mmus\Rhox2a, Mmus\Pax3, Mmus\Hoxc11, Mmus\Rhox4g, Mmus\Gbx1, Mmus\Rhox4f, Mmus\Pax2, Mmus\Pax4, Mmus\Rhox4c, Mmus\Arx, Mmus\Hoxd10, Mmus\Pax5, Mmus\Rhox6, Mmus\Rhox9, Mmus\Cphx1, Mmus\Pax6, Mmus\Duxbl1, Mmus\Rhox1, Mmus\Pax7, Mmus\Pax8" "Hsap\GBX1, Hsap\PAX1, Hsap\DUX4, Hsap\PAX4, Hsap\DUXA, Hsap\PAX2, Hsap\NKX2-6, Hsap\MIXL1, Hsap\PAX7, Hsap\PAX9, Hsap\PAX3, Hsap\PAX5, Hsap\PAX6, Hsap\PAX8, Hsap\ARX" " larval stage | third instar , larval stage | third instar--prepupal stage " " eye disc | dorsal && morphogenetic furrow | anterior to

, eye disc | anterior

, antennal disc | central

" "planar polarity defective,viable" "scutellum,microchaeta,ectopic,macrochaeta & scutumMS248,scutum,macrochaeta & scutumMD-638" FBgn0003300 run runt http://flybase.org/reports/FBgn0003300 "FBgn0019659, FBgn0019997, FBtr0077279, FBpp0076971" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000040 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "neuroblast fate determination ; GO:0007400 | traceable author statement eye morphogenesis ; GO:0048592 | inferred from mutant phenotype germ-band extension ; GO:0007377 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype periodic partitioning by pair rule gene ; GO:0007366 | non-traceable author statement germ-band extension ; GO:0007377 | traceable author statement sex determination, establishment of X:A ratio ; GO:0007540 | traceable author statement sex determination, establishment of X:A ratio ; GO:0007540 | non-traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype ventral cord development ; GO:0007419 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype periodic partitioning by pair rule gene ; GO:0007366 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "Runt, leg, AA33, l(1)AA33, P235, LB5, lLB5, 2, 1, l(1)LB9, l(1)B2/13.1, l(1)19Ea, CG1849, run, Run, runt, Rnt, RUN" "IPR000040:Acute myeloid leukemia 1 protein (AML1)/Runt, IPR008967:p53-like transcription factor, DNA-binding, IPR012346:p53/RUNT-type transcription factor, DNA-binding domain, IPR013524:Runt domain" CG1849 11-Aug-17 DroID_v2017_08 "Drer\runx1, Drer\runx3, Drer\runx2a, Drer\runx2b" - Cele\rnt-1 "Xtro\runx2, Xtro\runx3, Xtro\runx1" "Mmus\Runx2, Mmus\Runx3, Mmus\Runx1" "Hsap\RUNX1, Hsap\RUNX3, Hsap\RUNX2" " embryonic stage | embryonic cycle 14 , embryonic stage | stage 4-11 , embryonic stage | stage 4 , embryonic stage&&larval stage , embryonic stage | embryonic cycle 13 , embryonic stage , adult stage | female , embryonic stage | stage 7-11 " "

pair rule , embryonic head

, organism | 70-90% egg length

,

10-70% egg length , proctodeum | primordium

" " embryonic stage | stage 9-11 , embryonic stage | stage 9-10 , embryonic stage | stage 9,10 , embryonic stage , embryonic stage | stage >=7 , embryonic stage | stage 11 , embryonic stage | blastoderm , embryonic stage | stage >=11 " " procephalic neurogenic region | restricted

, ventral neurogenic region

, ganglion mother cell GMC4-2a

, neuroblast NB4-2

{ 0 wg- } , U neuron

,

segment polarity , neuroblast

, neuroblast NB5-3

{ 0 wg- } ,

pair rule , deuterocerebral neuroblast | subset

, neurectoderm | row 2/3

{ + wg- } , EL neuron

, neuroblast NB3-2

, embryonic head | resticted

, ganglion mother cell GMC3-2a

{ + wg- } , embryonic central nervous system

, embryonic peripheral nervous system

, neurectoderm | row 4

{ 0 wg- } , neuroblast NB5-3

{ + wg- } , ganglion mother cell

, protocerebral neuroblast | subset

" "neuroanatomy defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,pair rule phenotype,heat sensitive,wild-type,cell polarity defective,male sterile,viable,visible,partially,somatic clone" "denticle belt,outer photoreceptor cell,embryonic epidermis,heat sensitive,embryonic maxillary segment,mesothoracic segment,cell autonomous,abdominal segment 1,abdominal segment 3,abdominal segment 5,abdominal segment 7,somatic clone,abdominal segment 6,metathoracic segment,embryonic/first instar larval cuticle,abdominal vch1 neuron,embryonic segment,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,salivary gland,longitudinal connective,EL neuron,extended germ band embryo,abdominal segment 2,abdominal segment 4,abdominal segment 8,abdominal segment 9,abdominal segment 10,abdominal segment 11,lamina plexus | third instar larval stage,ventral nerve cord,ommatidium,eye,cephalopharyngeal skeleton,germ band" FBgn0020497 emb embargoed http://flybase.org/reports/FBgn0020497 FBgn0021807 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 protein transporter activity ; GO:0008565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Nup214 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9GYU8 multicellular organism development ; GO:0007275 | inferred from direct assay regulation of cellular response to hypoxia ; GO:1900037 | inferred from mutant phenotype nuclear export ; GO:0051168 | inferred from direct assay protein transport ; GO:0015031 | inferred from direct assay protein export from nucleus ; GO:0006611 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype ribosomal small subunit export from nucleus ; GO:0000056 | inferred from mutant phenotype nuclear membrane ; GO:0031965 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Crm1, crm1, CRM1, dCRM1, l(2)k16715, CG13387, emb, Emb, DCRM1, Xpo1, XPO1, XPO-1, dXPO1" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR013598:Exportin-1/Importin-beta-like, IPR014877:CRM1 C-terminal domain, IPR016024:Armadillo-type fold" CG13387 11-Aug-17 DroID_v2017_08 "Drer\xpo1a, Drer\xpo6, Drer\xpo5, Drer\xpo1b" "Scer\CRM1, Scer\MSN5" Cele\xpo-1 "Xtro\xpo6, Xtro\exd3, Xtro\xpo1, Xtro\xpo5" "Mmus\Xpo1, Mmus\Xpo5, Mmus\Xpo6" "Hsap\XPO5, Hsap\XPO1, Hsap\XPO6" embryonic stage " embryonic/larval midgut

, embryonic/larval somatic muscle

, embryonic/larval posterior spiracle

, ventral nerve cord

, embryonic brain

, embryonic/larval hindgut

,

ubiquitous " "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,stress response defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,partially lethal - majority die,some die during pupal stage" embryonic/larval tracheal system DRSC03528 I -0.451068959 1.878097167 0.320031123 -0.859883538 -0.279782875 0.33583141 FBgn0025700 CG5885 - http://flybase.org/reports/FBgn0025700 FBgn0032159 protein_coding_gene - SRP-dependent cotranslational protein targeting to membrane ; GO:0006614 | inferred from electronic annotation with InterPro:IPR009779 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009779 lipid particle ; GO:0005811 | inferred from direct assay "AI945207, CK01296, BEST:CK01296, CG5885" IPR009779:Translocon-associated protein subunit gamma CG5885 11-Aug-17 DroID_v2017_08 Drer\ssr3 - Cele\trap-3 Xtro\ssr3 Mmus\Ssr3 Hsap\SSR3 DRSC02910 E 1.320153552 0.340640512 1.779095734 -0.219277971 0.191617255 -0.701793886 FBgn0028374 Hug Hugin http://flybase.org/reports/FBgn0028374 protein_coding_gene "receptor binding ; GO:0005102 | inferred from sequence or structural similarity myostimulatory hormone activity ; GO:0016084 | inferred from direct assay hormone activity ; GO:0005179 | non-traceable author statement ecdysis-triggering hormone activity ; GO:0008255 | inferred from sequence or structural similarity with ETH neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with PK2-R2, PK2-R1" "ecdysis, chitin-based cuticle ; GO:0018990 | inferred from sequence or structural similarity with ETH inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern larval feeding behavior ; GO:0030536 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "hug-gamma, Drm-PK-2, HUGgamma, Drm-MT2, hug gamma, huggamma, pyrokinin/PBAN-like, CG6371, Hug-gamma, HUG, hugg, hug-1, hug-2, PK-2, hug-PK, Hugin-PK-2, Hug, hug, hugin" - CG6371 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,partially,small body,feeding behavior defective,lethal - all die before end of larval stage,some die during larval stage,viable" second instar larva DRSC16969 K 0.19908292 0.413276546 -0.534208533 0.630509807 2.673961164 1.926553085 FBgn0052103 CG32103 - http://flybase.org/reports/FBgn0052103 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 ADP transmembrane transporter activity ; GO:0015217 | inferred from biological aspect of ancestor with PANTHER:PTN000641656 ATP transmembrane transporter activity ; GO:0005347 | inferred from biological aspect of ancestor with PANTHER:PTN000641656 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG4392, CG18022, CG32103" "IPR002048:EF-hand domain, IPR002067:Mitochondrial carrier protein, IPR002167:Graves disease carrier protein, IPR011992:EF-hand domain pair, IPR018108:Mitochondrial substrate/solute carrier, IPR018247:EF-Hand 1, calcium-binding site, IPR023395:Mitochondrial carrier domain" CG32103 11-Aug-17 DroID_v2017_08 "Drer\slc25a25b, Drer\caln2, Drer\slc25a42, Drer\slc25a16, Drer\slc25a24, Drer\slc25a23a, Drer\slc25a23b, Drer\slc25a24l, Drer\slc25a25a" "Scer\YPR011C, Scer\SAL1, Scer\LEU5" "Cele\F17E5.2, Cele\slc-25A42, Cele\F55A11.4" "Xtro\slc25a42, Xtro\slc25a24, Xtro\slc25a23, Xtro\slc25a25" "Mmus\Slc25a25, Mmus\Slc25a54, Mmus\Slc25a41, Mmus\Caln1, Mmus\Slc25a23, Mmus\Slc25a16, Mmus\Slc25a24, Mmus\Slc25a42, Mmus\Cabp7" "Hsap\SLC25A16, Hsap\SLC25A41, Hsap\SLC25A24, Hsap\SLC25A25, Hsap\SLC25A23, Hsap\CALN1, Hsap\SLC25A42" viable DRSC10293 I 1.555558042 0.701393022 -0.725933318 0.466152263 -0.02119975 -0.134571573 FBgn0051867 CG31867 - http://flybase.org/reports/FBgn0051867 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6275, BcDNA:AT02643, CG31867" - CG31867 11-Aug-17 DroID_v2017_08 - - - - - - "viable,planar polarity defective,partially lethal - majority die,some die during pupal stage" DRSC03338 K -0.786339235 -0.630252753 -0.638950057 0.820413106 -0.433935584 1.918494093 FBgn0037387 CG1213 - http://flybase.org/reports/FBgn0037387 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "CT30783, CG1213" "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG1213 11-Aug-17 DroID_v2017_08 "Drer\LOC797974, Drer\slc2a12, Drer\si:dkey-229d11.5, Drer\slc2a8, Drer\si:ch1073-263o8.2, Drer\slc2a13b, Drer\slc2a6, Drer\LOC101882338, Drer\slc2a10" "Scer\VBA3, Scer\AZR1, Scer\VBA1, Scer\HXT8, Scer\VBA4, Scer\GEX1, Scer\HXT2, Scer\HXT13, Scer\MAL31, Scer\GEX2, Scer\ITR2, Scer\HXT10, Scer\ATR1, Scer\RGT2, Scer\YFL040W, Scer\YDL199C, Scer\GAL2, Scer\MPH3, Scer\HXT11, Scer\VBA5, Scer\HXT16, Scer\HXT1, Scer\ENB1, Scer\STL1, Scer\HXT17, Scer\SNF3, Scer\MPH2, Scer\HXT9, Scer\HXT4, Scer\HXT15, Scer\HXT5, Scer\HXT14, Scer\YMR279C, Scer\HXT3, Scer\SGE1, Scer\VBA2, Scer\HXT6, Scer\ITR1, Scer\YDR387C, Scer\HXT7, Scer\MAL11" "Cele\slcf-2, Cele\M01G12.9, Cele\hmit-1.1, Cele\M01G12.14, Cele\Y66D12A.21" "Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a12, Xtro\slc2a10" "Mmus\Slc2a8, Mmus\Slc2a12, Mmus\Tm2d1, Mmus\Pate3, Mmus\Slc2a10, Mmus\Slc2a13, Mmus\Slc2a6, Mmus\Gm17689, Mmus\Pate1, Mmus\1700013H16Rik, Mmus\Gm7257, Mmus\Gm5615, Mmus\Pate4, Mmus\Acrv1" "Hsap\PATE3, Hsap\PATE4, Hsap\SLC2A6, Hsap\PATE1, Hsap\SLC2A13, Hsap\SLC2A10, Hsap\SLC2A8, Hsap\TM2D1, Hsap\SLC2A12, Hsap\ACRV1" "viable,fertile" DRSC12191 I -1.565842805 -0.22975542 0.409357845 0.592876319 1.394030747 0.694593555 FBgn0086779 step steppke http://flybase.org/reports/FBgn0086779 protein_coding_gene "ARF guanyl-nucleotide exchange factor activity ; GO:0005086 | inferred from electronic annotation with InterPro:IPR000904 phosphatidylinositol-3,4,5-trisphosphate binding ; GO:0005547 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with step" regulation of ARF protein signal transduction ; GO:0032012 | inferred from electronic annotation with InterPro:IPR000904 regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype activation of MAPK activity ; GO:0000187 | inferred from mutant phenotype regulation of ARF protein signal transduction ; GO:0032012 | inferred by curator from GO:0005086 regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype cleavage furrow ; GO:0032154 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CYH1, CG11628, cytohesin/GRP1, GRP1/cytohesin 1, CG11633, step, GPH, l(2)k08110, l(2)SH0323, l(2)SH2 0323, Grp1, GRP1, stepk, Step" "IPR000904:Sec7 domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR023394:Sec7 domain, alpha orthogonal bundle" CG11628 11-Aug-17 DroID_v2017_08 "Drer\cyth4b, Drer\cyth1a, Drer\cyth3a, Drer\cyth4a, Drer\cyth3b, Drer\cyth1b, Drer\si:dkey-283b15.4" "Scer\SEC7, Scer\BOI2, Scer\SYT1, Scer\YEL1" Cele\grp-1 "Xtro\cyth4, Xtro\cyth2, Xtro\cyth3, Xtro\cyth1" "Mmus\Cyth2, Mmus\Cyth4, Mmus\Cyth1, Mmus\Cyth3" "Hsap\CYTH2, Hsap\CYTH1, Hsap\CYTH3, Hsap\CYTH4" DRSC03694 I 0.258075219 -4.185826467 -0.523682562 0.74607651 1.192565058 1.025020391 FBgn0260653 serp serpentine http://flybase.org/reports/FBgn0260653 protein_coding_gene chitin binding ; GO:0008061 | inferred from mutant phenotype chitin deacetylase activity ; GO:0004099 | inferred from mutant phenotype "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR002509, InterPro:IPR011330 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype" late endosome ; GO:0005770 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay basement membrane ; GO:0005604 | inferred from direct assay "Serp, serp, l(3)76BDk, CG8748, CG8747, CG32209, DmCDA1" "IPR002509:NodB homology domain, IPR002557:Chitin binding domain, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG32209 11-Aug-17 DroID_v2017_08 - - "Cele\lgx-1, Cele\F48E3.8" - - - DRSC11036 E 0.771510849 1.007442734 -0.144201215 1.597760301 0.926181987 -0.054183341 FBgn0032135 GlcAT-S GlcAT-S http://flybase.org/reports/FBgn0032135 protein_coding_gene "galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ; GO:0015018 | inferred from direct assay galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity ; GO:0046989 | inferred from direct assay N-acetyllactosamine beta-1,3-glucuronosyltransferase activity ; GO:0046987 | inferred from direct assay asioloorosomucoid beta-1,3-glucuronosyltransferase activity ; GO:0046988 | inferred from direct assay" glycoprotein biosynthetic process ; GO:0009101 | non-traceable author statement chondroitin sulfate proteoglycan biosynthetic process ; GO:0050650 | inferred from biological aspect of ancestor with PANTHER:PTN000855563 carbohydrate metabolic process ; GO:0005975 | inferred from biological aspect of ancestor with PANTHER:PTN000096174 proteoglycan biosynthetic process ; GO:0030166 | non-traceable author statement chondroitin sulfate metabolic process ; GO:0030204 | inferred from biological aspect of ancestor with PANTHER:PTN000855563 glycosphingolipid biosynthetic process ; GO:0006688 | non-traceable author statement membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005027 "DmGlcAT-BSI, CG3881, DGlcAT-S, GlcAT-S, dGlcAT-BSI, dGlcAT-S" "IPR005027:Glycosyl transferase, family 43, IPR029044:Nucleotide-diphospho-sugar transferases" CG3881 11-Aug-17 DroID_v2017_08 "Drer\b3gat1a, Drer\b3gat2, Drer\b3gat1b, Drer\b3gat3" - "Cele\glct-5, Cele\glct-2, Cele\glct-4, Cele\glct-3, Cele\glct-1, Cele\sqv-8, Cele\glct-6" "Xtro\b3gat2, Xtro\b3gat3, Xtro\b3gat1" "Mmus\B3gat2, Mmus\B3gat3, Mmus\B3gat1" "Hsap\B3GAT3, Hsap\B3GAT2, Hsap\B3GAT1" embryonic stage -- adult stage "viable,fertile" DRSC27771 K 0.432317573 -0.996885559 -0.896703137 0.406812834 0.825625583 2.487111237 FBgn0027091 CysRS Cysteinyl-tRNA synthetase http://flybase.org/reports/FBgn0027091 FBgn0027536 protein_coding_gene ATP binding ; GO:0005524 | inferred from biological aspect of ancestor with PANTHER:PTN000095308 cysteine-tRNA ligase activity ; GO:0004817 | inferred from sequence or structural similarity with UniProtKB:P49589 cysteine-tRNA ligase activity ; GO:0004817 | traceable author statement tRNA binding ; GO:0000049 | inferred from sequence or structural similarity with UniProtKB:P49589 cysteinyl-tRNA aminoacylation ; GO:0006423 | traceable author statement cysteinyl-tRNA aminoacylation ; GO:0006423 | inferred from sequence or structural similarity with UniProtKB:P49589 cytoplasm ; GO:0005737 | traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P49589 "CG8431, CysRS, CRS, BcDNA:LD21177, Aats-cys" "IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR015803:Cysteine-tRNA ligase, IPR032678:tRNA synthetases class I, catalytic domain, IPR024909:Cysteinyl-tRNA synthetase/mycothiol ligase, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding" CG8431 11-Aug-17 DroID_v2017_08 "Drer\cars, Drer\cars2" Scer\YNL247W Cele\cars-1 "Xtro\cars, Xtro\cars2" "Mmus\Cars, Mmus\Cars2" "Hsap\CARS, Hsap\CARS2" embryonic stage

ubiquitous "lethal,partially lethal - majority die,visible" mesothoracic tergum DRSC05948 I -1.815978701 -0.158975055 0.412933527 -0.226250412 0.142410218 -0.920854791 FBgn0264491 how held out wings http://flybase.org/reports/FBgn0264491 protein_coding_gene single-stranded RNA binding ; GO:0003727 | inferred from electronic annotation with InterPro:IPR031119 mRNA binding ; GO:0003729 | inferred from direct assay mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay "regulation of translation ; GO:0006417 | inferred from electronic annotation with InterPro:IPR031119 regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype oenocyte development ; GO:0007438 | inferred from mutant phenotype cell differentiation ; GO:0030154 | traceable author statement germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern axon ensheathment ; GO:0008366 | inferred from mutant phenotype spermatogonial cell division ; GO:0007284 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from mutant phenotype mesodermal cell migration ; GO:0008078 | inferred from mutant phenotype regulation of heart contraction ; GO:0008016 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype muscle cell fate determination ; GO:0007521 | inferred from direct assay somatic muscle development ; GO:0007525 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 "how, HOW, 0904/17, l(3)S090417, l(3)S053606, 24B, How, CG10293, who, Who/How, sci, P62, qkr[93F], stru, qkr, l(3)j5B5, SZ1, anon-EST:Liang-2.39, clone 2.39, l(3)s2612, l(3)j5D5, KH93F" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR031119:STAR-domain RNA-binding protein GLD-1/HOW, IPR032377:STAR protein, homodimerisation region" CG10293 11-Aug-17 DroID_v2017_08 "Drer\qki2, Drer\qkia, Drer\khdrbs3, Drer\khdrbs2, Drer\khdrbs1b, Drer\khdrbs1a, Drer\qkib" Scer\MSL5 "Cele\Y69A2AR.32, Cele\Y57G11C.36, Cele\gld-1, Cele\K07H8.9, Cele\asd-2, Cele\F54D1.1, Cele\E02D9.1, Cele\B0280.17" "Xtro\khdrbs3, Xtro\khdrbs2, Xtro\khdrbs1, Xtro\qki" "Mmus\Khdrbs1, Mmus\Khdrbs3, Mmus\Khdrbs2, Mmus\Qk" "Hsap\KHDRBS2, Hsap\QKI, Hsap\KHDRBS1, Hsap\KHDRBS3" " embryonic stage | stage >=15 , embryonic stage | stage >=6 , embryonic stage , embryonic stage | stage 6 , embryonic stage | stage >=14 , embryonic stage -- adult stage , embryonic stage | early , adult stage | female , embryonic stage | stage 12 , embryonic stage | late , embryonic stage | stage 14 , embryonic stage | stage 6,7 , pupal stage , embryonic stage&&pupal stage " " embryonic/larval somatic muscle

, mesoderm

, mesoderm anlage

, ventral furrow

, muscle attachment site

, embryonic/larval heart

, visceral mesoderm

, pharyngeal muscle

, larval visceral muscle

, embryonic/larval dorsal vessel

, myoblast &&of larval muscle system

, embryonic/larval aorta

, somatic mesoderm

" " larval stage , embryonic stage | stage 14 , embryonic stage | stage >=14 , adult stage , embryonic stage | stage >7 , embryonic stage | stage >=15 , embryonic stage | stage 6,7 , embryonic stage | stage 6-7 , adult stage && oogenesis stage " " imaginal disc

, cardioblast

, muscle attachment site

, hindgut muscle

, mesoderm

, pharyngeal muscle

, embryonic/larval aorta

, cephalic furrow

, head mesoderm

, muscle fiber &&of larval muscle system

, ventral furrow

, adepithelial cell

, larval visceral muscle

, embryonic/larval somatic muscle

, mesoderm anlage

, interfollicle cell

, tendon cell

, embryonic/larval dorsal vessel

" DRSC25008 IEK -1.605999246 -2.809241145 -1.661924498 -1.561220948 0.708623265 4.482111321 FBgn0004862 bap bagpipe http://flybase.org/reports/FBgn0004862 FBgn0002943 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from genetic interaction with βTub60D DNA binding ; GO:0003677 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" mesoderm development ; GO:0007498 | inferred from expression pattern visceral muscle development ; GO:0007522 | non-traceable author statement midgut development ; GO:0007494 | traceable author statement mesodermal cell fate commitment ; GO:0001710 | traceable author statement mesodermal cell fate specification ; GO:0007501 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype heart development ; GO:0007507 | non-traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0003677 "Bap1, NK-3, dNK-3, NK3, bgp, nk-3, CG7902, bap, Bap, BAP, bag, Nkx3.2" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR020479:Homeobox domain, metazoa" CG7902 11-Aug-17 DroID_v2017_08 "Drer\nkx2.4a, Drer\nkx3-1, Drer\nkx2.2b, Drer\nkx2.1, Drer\nkx3.3, Drer\nkx2.5, Drer\nkx3.2, Drer\nkx2.4b, Drer\nkx2.7, Drer\nkx2.2a, Drer\nkx2.3" - "Cele\unc-30, Cele\lim-7" "Xtro\nkx2-2, Xtro\nkx3-1, Xtro\nkx3-3, Xtro\nkx2-6, Xtro\nkx2-1, Xtro\nkx3-2, Xtro\nkx2-3, Xtro\nkx2-5, Xtro\nkx2-8" "Mmus\Nkx2-3, Mmus\Nkx3-2, Mmus\Nkx2-1, Mmus\Nkx3-1, Mmus\Nkx2-6, Mmus\Nkx2-5, Mmus\Nkx2-2, Mmus\Nkx2-9, Mmus\Nkx2-4" "Hsap\NKX2-8, Hsap\NKX2-4, Hsap\NKX2-5, Hsap\NKX3-2, Hsap\NKX2-1, Hsap\NKX2-3, Hsap\NKX3-1, Hsap\NKX2-6, Hsap\NKX2-2" " embryonic stage | stage >12 , embryonic stage | stage 11-15 , embryonic stage | stage 10-11 , embryonic stage " " cardioblast

, visceral mesoderm &&of embryonic/larval foregut

, visceral mesoderm &&of embryonic/larval midgut

, mesoderm | dorsal

, visceral mesoderm &&of embryonic/larval hindgut

" "wild-type,lethal" "midgut muscle,embryonic/larval midgut" FBgn0261854 aPKC atypical protein kinase C http://flybase.org/reports/FBgn0261854 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR012233, InterPro:IPR017441, InterPro:IPR017892 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A protein binding ; GO:0005515 | inferred from physical interaction with Patj inferred from physical interaction with crb protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" "compound eye retinal cell programmed cell death=0046667 |... direct assay <> adherens junction organization=0034332 |... mutant phenotype <> terminal branching, open tracheal system=0007430 |... mutant phenotype <> establishment or maintenance of neuroblast polarity=0045196 | non-traceable author statement <> establishment or maintenance of epithelial cell apical/basal polarity=0045197 | traceable author statement <> synapse assembly=0007416 |... mutant phenotype <> protein localization to plasma membrane=0072659 |... mutant phenotype <> germarium-derived oocyte fate determination=0007294 |... mutant phenotype <> asymmetric protein localization involved in cell fate determination=0045167 |... physical interaction with par-6 <> establishment of epithelial cell planar polarity=0090163 |... mutant phenotype inferred from genetic interaction with sgg <> epithelial cell morphogenesis=0003382 |... mutant phenotype inferred from genetic interaction with sgg <> protein phosphorylation=0006468 | non-traceable author statement <> zonula adherens assembly=0045186 | traceable author statement <> memory=0007613 |... mutant phenotype <> oocyte anterior/posterior axis specification=0007314 |... genetic interaction with l(2)gl <> protein phosphorylation=0006468 |... direct assay <> intracellular signal transduction=0035556 |... biological aspect of ancestor with PANTHER:PTN000683254 <> regulation of polarized epithelial cell differentiation=0030860 |... mutant phenotype <> melanotic encapsulation of foreign target=0035011 |... mutant phenotype <> establishment of epithelial cell apical/basal polarity=0045198 |... genetic interaction with yrt <> zonula adherens assembly=0045186 | non-traceable author statement <> positive regulation of neuroblast proliferation=0002052 |... mutant phenotype <> establishment or maintenance of polarity of embryonic epithelium=0016332 |... mutant phenotype <> morphogenesis of a polarized epithelium=0001738 | traceable author statement <> establishment or maintenance of epithelial cell apical/basal polarity=0045197 |... mutant phenotype <> exocyst localization=0051601 |... mutant phenotype <> establishment or maintenance of cell polarity=0007163 | non-traceable author statement <> establishment or maintenance of neuroblast polarity=0045196 |... genetic interaction with l(2)gl <> cell-cell junction assembly=0007043 | non-traceable author statement <> establishment or maintenance of cell polarity=0007163 |... mutant phenotype <> cuticle development=0042335 |... genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 <> establishment or maintenance of polarity of embryonic epithelium=0016332 | non-traceable author statement <> branching involved in open tracheal system development=0060446 |... mutant phenotype <> maintenance of cell polarity=0030011 |... mutant phenotype <> spermatogenesis=0007283 |... mutant phenotype <> peptidyl-serine phosphorylation=0018105 |... biological aspect of ancestor with PANTHER:PTN000683254 <> establishment or maintenance of epithelial cell apical/basal polarity=0045197 | non-traceable author statement <> asymmetric neuroblast division=0055059 |... genetic interaction with pins <> positive regulation of filopodium assembly=0051491 |... mutant phenotype <> apical protein localization=0045176 | non-traceable author statement <> establishment or maintenance of polarity of follicular epithelium=0016334 |... mutant phenotype <> establishment of mitotic spindle orientation=0000132 |... mutant phenotype <> positive regulation of lamellipodium assembly=0010592 |... mutant phenotype <> establishment or maintenance of neuroblast polarity=0045196 |... mutant phenotype <> sensory organ development=0007423 |... mutant phenotype <> oocyte axis specification=0007309 | traceable author statement" apical cortex ; GO:0045179 | inferred from direct assay subapical complex ; GO:0035003 | traceable author statement cell cortex ; GO:0005938 | traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay apical cortex ; GO:0045179 | non-traceable author statement apical plasma membrane ; GO:0016324 | non-traceable author statement apicolateral plasma membrane ; GO:0016327 | inferred from direct assay apical plasma membrane ; GO:0016324 | traceable author statement "CG42783, aPKC, aPKCzeta, DaPKC, aPKC-zeta, dapkc, psu, apkc, pkc-3, CG10261, l(2)k06403, PKCl,i, daPKC, a-PKC, CG30475, alphaPKCzeta, PKCzeta, aPkc" "IPR034659:Atypical protein kinase C, catalytic domain, IPR000270:PB1 domain, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR012233:Protein kinase C, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal, IPR020454:Diacylglycerol/phorbol-ester binding" CG42783 11-Aug-17 DroID_v2017_08 "Drer\prkci, Drer\prkcz" Scer\PKC1 Cele\pkc-3 "Xtro\prkci, Xtro\prkcz" "Mmus\Prkcz, Mmus\Prkci" "Hsap\PRKCZ, Hsap\PRKCI" pupal stage photoreceptor cell stalk | apical

FBgn0011227 ox oxen http://flybase.org/reports/FBgn0011227 "FBgn0024946, FBgn0026780, FBgn0047014" protein_coding_gene ubiquinol-cytochrome-c reductase activity ; GO:0008121 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000312316 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:Q9UDW1 "spermatid development ; GO:0007286 | inferred from mutant phenotype aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000312316 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:Q9UDW1 mitochondrial respiratory chain complex III assembly ; GO:0034551 | inferred from biological aspect of ancestor with PANTHER:PTN000312316 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000312316" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:Q9UDW1 mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN000312316 "QCR9, Qcr9, ms(2)00815, Qcr10, CG8764, BcDNA:RH44662, ox, UCRX, UQCR-7.2" IPR008027:Cytochrome b-c1 complex subunit 9 CG8764 11-Aug-17 DroID_v2017_08 Drer\LOC100333064 Scer\QCR9 Cele\C14B9.10 Xtro\uqcr10 Mmus\Uqcr10 Hsap\UQCR10 " embryonic stage | stage 5-11 , embryonic stage | stage 13 , embryonic stage | stage 13-17 " "

ubiquitous , amnioserosa

, embryonic/larval midgut

" "viable,fertile,male sterile,recessive,partially lethal - majority die,wild-type,lethal,cell lethalcell lethal,somatic clone,visible,some die during pupal stage" "oocyte,germline clone,trichogen cell" FBgn0004882 orb oo18 RNA-binding protein http://flybase.org/reports/FBgn0004882 - protein_coding_gene "translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 protein binding ; GO:0005515 | inferred from physical interaction with bru1 inferred from physical interaction with BicC mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA 3'-UTR binding ; GO:0003730 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VYS4 translation factor activity, RNA binding ; GO:0008135 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 mRNA binding ; GO:0003729 | traceable author statement ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000286163" "pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype regulation of oskar mRNA translation ; GO:0046011 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype embryonic axis specification ; GO:0000578 | traceable author statement dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype inferred from genetic interaction with rin oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype regulation of oskar mRNA translation ; GO:0046011 | traceable author statement germarium-derived oocyte fate determination ; GO:0007294 | traceable author statement pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement intracellular mRNA localization ; GO:0008298 | traceable author statement oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | traceable author statement negative regulation of cytoplasmic translation ; GO:2000766 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 pole plasm assembly ; GO:0007315 | non-traceable author statement positive regulation of oskar mRNA translation ; GO:0046012 | non-traceable author statement germ cell development ; GO:0007281 | traceable author statement inferred from mutant phenotype oocyte axis specification ; GO:0007309 | traceable author statement pole plasm oskar mRNA localization ; GO:0045451 | non-traceable author statement oogenesis ; GO:0048477 | traceable author statement" messenger ribonucleoprotein complex ; GO:1990124 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000286163 intracellular ribonucleoprotein complex ; GO:0030529 | colocalizes_with inferred from physical interaction with rin "orb, Orb, 151666_s_at, ORB, oo18, fs(3)00107, CG10868, oo18 RNA-binding protein, Oo18, Orb1" "IPR000504:RNA recognition motif domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032296:Cytoplasmic polyadenylation element-binding protein, ZZ domain" CG10868 11-Aug-17 DroID_v2017_08 "Drer\cpeb4, Drer\cpeb1b, Drer\cpeb3, Drer\cpeb1a" - "Cele\cpb-3, Cele\cpb-2, Cele\fog-1, Cele\cpb-1" "Xtro\cpeb3, Xtro\cpeb2, Xtro\cpeb1, Xtro\cpeb4" "Mmus\Cpeb3, Mmus\Cpeb2, Mmus\Cpeb4, Mmus\Cpeb1" "Hsap\AP3B2, Hsap\CPEB1, Hsap\CPEB2" " larval stage | third instar , embryonic stage | stage 4-8 , spermatogenesis && adult stage , adult stage && oogenesis stage | stage S11-14 , pupal stage && adult stage , adult stage && oogenesis stage | stage S8-10 , adult stage && oogenesis stage | stage S1-6 , adult stage && oogenesis stage | stage S7 , larval stage--adult stage | male && spermatogenesis , embryonic stage | early " " pole cell

, spermatid

, oocyte | ubiquitous

, oocyte | anterior

, nurse cell

, testis

,

posterior , spermatocyte

" " adult stage && oogenesis stage | stage S8-10 , oogenesis stage | stage S8-10 " " nurse cell

, oocyte

" "female sterile,recessive,viable,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,sterile,dominant,partially,germline clone,lethal,partially lethal - majority die,visible,some die during pupal stage" "ovary,chorion | maternal effect,egg chamber,egg,oocyte,embryonic abdomen,dorsal appendage,chorion,chorion | maternal effect, with orb8E2Hd.Hsp83.TEcollacZ,synaptonemal complex | ectopic,germline cyst,maternal effect,dorsal,synaptonemal complex,embryo,posterior,chorion | maternal effect, with orbF343,trichogen cell,mesothoracic tergum" FBgn0004167 kst karst http://flybase.org/reports/FBgn0004167 FBgn0010743 protein_coding_gene phospholipid binding ; GO:0005543 | inferred from electronic annotation with InterPro:IPR001605 protein binding ; GO:0005515 | inferred from physical interaction with AnxB9 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from direct assay endocytosis ; GO:0006897 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement wound healing ; GO:0042060 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype plasma membrane organization ; GO:0007009 | traceable author statement regulation of multivesicular body size involved in endosome transport ; GO:0010797 | inferred from mutant phenotype endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype zonula adherens assembly ; GO:0045186 | traceable author statement spectrin ; GO:0008091 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay actin filament bundle ; GO:0032432 | colocalizes_with inferred from direct assay apicolateral plasma membrane ; GO:0016327 | traceable author statement "betaH-Spec, beta[[H]], beta[[H]]-SPEC, beta[[heavy]]spectrin, beta[[H]]-Spectrin, betaH, beta[[heavy]]-Spectrin, CG12008, beta[[H]]spectrin, beta[[Heavy]]spectrin, beta[[heavy]]-Spec, l(3)01318, Spec-beta[[H]], kst, betah-Spec, betaHS, Kst, beta[[H]]-Spec, beta[[H]]-Sp, beta-Spectrin, betaHSpec" "IPR018159:Spectrin/alpha-actinin, IPR001452:SH3 domain, IPR001589:Actinin-type actin-binding domain, conserved site, IPR001605:Pleckstrin homology domain, spectrin-type, IPR001715:Calponin homology domain, IPR001849:Pleckstrin homology domain, IPR002017:Spectrin repeat, IPR011993:PH domain-like" CG12008 11-Aug-17 DroID_v2017_08 "Drer\sptbn5, Drer\actn3a, Drer\sptb, Drer\actn1, Drer\LOC558044, Drer\ehbp1, Drer\sptbn1, Drer\ehbp1l1b, Drer\actn2b, Drer\si:dkey-27p18.5, Drer\spna2, Drer\actn3b, Drer\actn4, Drer\zgc:165653" - "Cele\sma-1, Cele\atn-1, Cele\spc-1, Cele\unc-70" "Xtro\sptbn2, Xtro\ehbp1, Xtro\sptan1, Xtro\ehbp1l1, Xtro\sptbn5, Xtro\actn3, Xtro\actn4, Xtro\actn2, Xtro\actn1" "Mmus\Actn2, Mmus\Sptbn5, Mmus\Sptbn1, Mmus\Sptan1, Mmus\Sptb, Mmus\Actn4, Mmus\Ehbp1l1, Mmus\Sptbn2, Mmus\Spta1, Mmus\Sptbn4, Mmus\Ehbp1, Mmus\Actn3, Mmus\Actn1" "Hsap\SPTBN1, Hsap\ACTN4, Hsap\SPTBN5, Hsap\ACTN1, Hsap\SPTBN2, Hsap\SPTAN1, Hsap\EHBP1L1, Hsap\SPTA1, Hsap\EHBP1, Hsap\SPTB, Hsap\ACTN3, Hsap\ACTN2, Hsap\SPTBN4" " adult stage && oogenesis stage | early , larval stage , adult stage | female && oogenesis stage | early , oogenesis stage && adult stage | female " " follicle cell

, salivary gland

, germline stem cell

" "partially lethal - majority die,recessive,viable,visible,lethal,lethal - all die before end of larval stage,some die during larval stage,sterile,partially" "embryonic/larval midgut,follicle cell,eye,macrochaeta,ectopic,rhabdomere,somatic clone,eye photoreceptor cell stalk,wing,ommatidium,photoreceptor cell R7,adult tracheal system,border follicle cell,oocyte,centripetally migrating follicle cell,nurse cell,wing & epithelial cell,embryonic/larval cuprophilic cell" FBgn0002638 Rcc1 Regulator of chromosome condensation 1 http://flybase.org/reports/FBgn0002638 FBgn0041146 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay Ran guanyl-nucleotide exchange factor activity ; GO:0005087 | inferred from sequence or structural similarity with HGNC:1913 regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from direct assay regulation of mitotic cell cycle ; GO:0007346 | inferred from direct assay NLS-bearing protein import into nucleus ; GO:0006607 | inferred from mutant phenotype regulation of nucleocytoplasmic transport ; GO:0046822 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype condensed chromosome ; GO:0000793 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "RanGEF, RCC1, CG18640 (Bj1), sdt, BJ1, inxs, CG10480, Rcc1, Bj1, dRCC1" "IPR000408:Regulator of chromosome condensation, RCC1, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II" CG10480 11-Aug-17 DroID_v2017_08 "Drer\als2a, Drer\rccd1, Drer\rcc1, Drer\als2b, Drer\ftr97, Drer\rpgrb, Drer\rcbtb2, Drer\herc2, Drer\wbscr16, Drer\herc1, Drer\rpgra, Drer\rcbtb1, Drer\sergef" "Scer\FMP25, Scer\ATS1, Scer\SRM1" Cele\ran-3 "Xtro\wbscr16, Xtro\rcc1, Xtro\als2cl, Xtro\rcbtb1, Xtro\rcbtb2, Xtro\herc2, Xtro\nek9, Xtro\als2, Xtro\herc1" "Mmus\Sergef, Mmus\Als2, Mmus\Rpgr, Mmus\Rccd1, Mmus\Rcbtb1, Mmus\Wbscr16, Mmus\Herc1, Mmus\Gm15800, Mmus\Rcc1, Mmus\Herc2, Mmus\Nek9, Mmus\Rcbtb2" "Hsap\SERGEF, Hsap\NEK9, Hsap\RCC1, Hsap\RCC1L, Hsap\RCBTB1, Hsap\RCCD1, Hsap\HERC1, Hsap\HECTD4, Hsap\RCBTB2, Hsap\HERC2, Hsap\ALS2, Hsap\RPGR" " embryonic stage | early , adult stage && oogenesis stage , embryonic stage " " nurse cell

, neuroblast

, oocyte

" " embryonic stage , adult stage && oogenesis stage , larval stage " " embryonic central nervous system

, neuroblast

, oocyte

, embryonic/larval salivary gland

, nurse cell

" "lethal,germline clone,cell lethalcell lethal,somatic clone,viable,fertile,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "EL neuron,central nervous system,lateral,eye,eye photoreceptor cell,ommatidium,anterior fascicle & synapse,intersegmental nerve,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0004574 Rop Ras opposite http://flybase.org/reports/FBgn0004574 FBgn0014289 protein_coding_gene SNARE binding ; GO:0000149 | inferred from sequence or structural similarity vesicle docking involved in exocytosis ; GO:0006904 | inferred from electronic annotation with InterPro:IPR001619 chemical synaptic transmission ; GO:0007268 | traceable author statement regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from direct assay ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype synaptic vesicle priming ; GO:0016082 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity positive regulation of dendrite development ; GO:1900006 | inferred from mutant phenotype secretion by cell ; GO:0032940 | inferred from direct assay response to light stimulus ; GO:0009416 | inferred from mutant phenotype synaptic vesicle transport ; GO:0048489 | traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | traceable author statement neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype exocytosis ; GO:0006887 | traceable author statement membrane ; GO:0016020 | traceable author statement cytosol ; GO:0005829 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement cytosol ; GO:0005829 | traceable author statement extrinsic component of membrane ; GO:0019898 | inferred from direct assay "Rop, ROP, rop(Sec1), l(3)64Ah, rop, CG15811, ras2, l(3)SH16, cs1, SEC1" IPR001619:Sec1-like protein CG15811 11-Aug-17 DroID_v2017_08 "Drer\stxbp1a, Drer\stxbp1b, Drer\stxbp3, Drer\stxbp2" Scer\SEC1 "Cele\T07A9.10, Cele\unc-18" "Xtro\stxbp1, Xtro\stxbp3, Xtro\stxbp2" "Mmus\Stxbp2, Mmus\Stxbp1, Mmus\Stxbp3" "Hsap\STXBP2, Hsap\STXBP1, Hsap\STXBP3" embryonic stage " central nervous system

, garland cell

, embryonic peripheral nervous system

, antenno-maxillary complex

" " embryonic stage | stage >=13 , embryonic stage | stage >=16 , embryonic stage | stage >=14 , larval stage | third instar , embryonic stage " " epidermis

, segmental nerve

, Malpighian tubule

, Bolwig's nerve

, intersegmental nerve

, larval muscle system

, neuropil

, embryonic/larval digestive system

, embryonic central nervous system

, embryonic/larval salivary gland

, imaginal disc

, garland cell

, bouton

" "lethal,recessive,neurophysiology defective,heat sensitive,partially lethal - majority die,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage" "central nervous system,egg,germline clone,oocyte,embryonic/first instar larval cuticle,tracheal branch primordium" FBgn0034900 CG12491 - http://flybase.org/reports/FBgn0034900 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12491 - CG12491 11-Aug-17 DroID_v2017_08 - - - - - - DRSC26465 K 0.136071702 0.771067704 0.78880305 0.056185984 -0.34816548 -1.643721387 FBgn0030556 mRNA-cap mRNA-capping-enzyme http://flybase.org/reports/FBgn0030556 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 polynucleotide 5'-phosphatase activity ; GO:0004651 | inferred from electronic annotation with InterPro:IPR017074 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement mRNA guanylyltransferase activity ; GO:0004484 | inferred from sequence or structural similarity with SGD:S000003098 "7-methylguanosine mRNA capping ; GO:0006370 | inferred from electronic annotation with InterPro:IPR001339, InterPro:IPR017074 protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000340 protein dephosphorylation ; GO:0006470 | non-traceable author statement" nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000003098 "PIR, CG1810, mRNA-cap, mRNA-capping-enzyme" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR001339:mRNA capping enzyme, catalytic domain, IPR012340:Nucleic acid-binding, OB-fold, IPR013846:mRNA capping enzyme, C-terminal, IPR016130:Protein-tyrosine phosphatase, active site, IPR017074:mRNA capping enzyme, bifunctional, IPR029021:Protein-tyrosine phosphatase-like" CG1810 11-Aug-17 DroID_v2017_08 "Drer\dusp11, Drer\rngtt" Scer\CEG1 Cele\cel-1 "Xtro\rngtt, Xtro\dusp11.2" "Mmus\Rngtt, Mmus\Dusp11" "Hsap\RNGTT, Hsap\DUSP11" DRSC19789 I -1.681431998 2.632845594 -0.608769398 0.192762353 0.873918614 0.76231957 FBgn0085444 mute muscle wasted http://flybase.org/reports/FBgn0085444 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003822 neurogenesis ; GO:0022008 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype" histone locus body ; GO:0035363 | inferred from direct assay "CG33455, CG15610, CG33456, mute, Mute, CG34415" IPR003822:Paired amphipathic helix CG34415 11-Aug-17 DroID_v2017_08 "Drer\gon4l, Drer\si:dkey-27c15.3" - Cele\gon-4 Xtro\gon4l Mmus\Gon4l "Hsap\GON4L, Hsap\YY1AP1" "lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,germline clone,recessive,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval somatic muscle,ganglion mother cell" DRSC22931 IE -2.345544283 -1.312885613 -2.372607171 -3.272950903 0.703371717 0.405701852 FBgn0010198 RpS15Aa Ribosomal protein S15Aa http://flybase.org/reports/FBgn0010198 "FBgn0025291, FBgn0030473" protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000630 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "CG2033, S15, RpS15A, anon-EST:Posey44, RpS15a, RpS15Aa, S15Aa, Rp S15 Aa" IPR000630:Ribosomal protein S8 CG2033 11-Aug-17 DroID_v2017_08 Drer\rps15a "Scer\RPS22B, Scer\RPS22A" Cele\rps-22 Xtro\rps15a Mmus\Rps15a Hsap\RPS15A "lethal,partially lethal - majority die,size defective" adult heart DRSC06129 EK -1.026518644 -0.756498897 1.519949629 -2.823516732 1.299159812 4.278623486 FBgn0011305 Rsf1 Repressor splicing factor 1 http://flybase.org/reports/FBgn0011305 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | traceable author statement "regulation of mRNA 3'-end processing ; GO:0031440 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype regulation of transcriptional start site selection at RNA polymerase II promoter ; GO:0001178 | inferred from mutant phenotype negative regulation of mRNA splicing, via spliceosome ; GO:0048025 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "RSF1, CG5655, Rox21, rox21, ROX21, Rsf1, dRSF1" IPR000504:RNA recognition motif domain CG5655 11-Aug-17 DroID_v2017_08 "Drer\srsf7a, Drer\cirbpb, Drer\srsf3a, Drer\srsf3b, Drer\srsf7b, Drer\cirbpa" "Scer\RNA15, Scer\NPL3" "Cele\Y57G11A.5, Cele\R09B3.2, Cele\R09B3.3, Cele\rsp-6" "Xtro\srsf3, Xtro\srsf7, Xtro\cirbp" "Mmus\Srsf3, Mmus\Srsf7, Mmus\Rbm3, Mmus\Cirbp" "Hsap\SRSF8, Hsap\SRSF7, Hsap\RBM3, Hsap\SRSF3" "visible,lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "eye,retina,macrochaeta" DRSC21953 K -1.279895246 0.160715105 -0.792926664 -0.165171915 0.524180928 1.950456959 FBgn0037344 CG2926 - http://flybase.org/reports/FBgn0037344 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965 zinc ion binding ; GO:0008270 | inferred from sequence model" "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0000381 CG2926 "IPR001841:Zinc finger, RING-type, IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR017907:Zinc finger, RING-type, conserved site, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2926 11-Aug-17 DroID_v2017_08 "Drer\phrf1, Drer\scaf11, Drer\scaf1" Scer\BMT6 - "Xtro\scaf1, Xtro\phrf1" "Mmus\Phrf1, Mmus\Scaf11, Mmus\Scaf1" "Hsap\SCAF11, Hsap\SCAF1, Hsap\PHRF1" "viable,fertile,visible" "chaeta,supernumerary" DRSC12321 IE 0.058743841 -2.317297617 2.507399074 -0.476914823 0.170233085 0.130572461 FBgn0003048 pcx pecanex http://flybase.org/reports/FBgn0003048 "FBgn0000752, FBgn0026853" protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007735 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "pcx, EG:30B8.4, CG3443, DMPCX, fs(1)pcx, mel(1)R1, fs(1)M10, mel(1)R, fs(1)A387, fs(1)14-567, fs(1)14-1153, fs(1)12-4169, fs(1)12-3102, fs(1)12-3014, fs(1)12-2135, fs(1)12-1743, fs(1)12-1012" IPR007735:Pecanex CG3443 11-Aug-17 DroID_v2017_08 "Drer\pcnxl4, Drer\pcnxl2, Drer\pcnx" - Cele\B0511.12 "Xtro\pcnx, Xtro\pcnxl2, Xtro\pcnxl4" "Mmus\Pcnx3, Mmus\Pcnx2, Mmus\Pcnx, Mmus\Pcnx4" "Hsap\PCNX2, Hsap\PCNX4, Hsap\PCNX1, Hsap\PCNX3" "female sterile,recessive,wild-type,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,neurogenic phenotype,viable,visible" "egg,maternal effect,endoplasmic reticulum | maternal effect,presumptive embryonic/larval central nervous system,embryonic/first instar larval cuticle,ventral,chaeta,supernumerary" DRSC18190 I 1.504312556 -0.338309762 -0.521360591 0.241430014 0.016361419 -0.238104751 FBgn0025638 Roc1a Regulator of cullins 1a http://flybase.org/reports/FBgn0025638 "FBgn0025527, FBgn0025705" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR024766 cullin family protein binding ; GO:0097602 | inferred from physical interaction with Cul1 cullin family protein binding ; GO:0097602 | inferred from physical interaction with UniProtKB:Q8IP45 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay cullin family protein binding ; GO:0097602 | inferred from physical interaction with Cul1 inferred from physical interaction with Cul2 inferred from physical interaction with Cul4 inferred from physical interaction with Cul3 zinc ion binding ; GO:0008270 | non-traceable author statement" neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay neuron remodeling ; GO:0016322 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype proteolysis ; GO:0006508 | traceable author statement proteolysis ; GO:0006508 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from direct assay smoothened signaling pathway ; GO:0007224 | non-traceable author statement Cul2-RING ubiquitin ligase complex ; GO:0031462 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from direct assay SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay Cul4-RING E3 ubiquitin ligase complex ; GO:0080008 | inferred from direct assay SCF ubiquitin ligase complex ; GO:0019005 | non-traceable author statement "CG16982, Roc1alpha, Rbx1/Roc, Rbx1, EG:115C2.11, dRbx1, ROC1, dRoc1a, CK01110, anon-EST:Posey65, BEST:CK01110, Roc1a, dRoc1, Roc, roc1a" "IPR001841:Zinc finger, RING-type, IPR024766:Zinc finger, RING-H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG16982 11-Aug-17 DroID_v2017_08 "Drer\rbx1, Drer\rnf7" Scer\HRT1 "Cele\rbx-2, Cele\rbx-1" "Xtro\rbx1, Xtro\rnf7" "Mmus\Gm9840, Mmus\Rbx1, Mmus\Rnf7" "Hsap\RBX1, Hsap\RNF7" " larval stage , embryonic stage -- adult stage " " dorsal mesothoracic disc

ubiquitous , organism

" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC18483 K -1.085685316 0.01639769 0.534721498 -1.216617104 2.767043778 2.364761323 FBgn0031213 galectin galectin http://flybase.org/reports/FBgn0031213 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR001079 galactoside binding ; GO:0016936 | inferred from direct assay synaptic target recognition ; GO:0008039 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG11372, Dmgal, galectin" "IPR001079:Galectin, carbohydrate recognition domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG11372 11-Aug-17 DroID_v2017_08 "Drer\lgals9l1, Drer\si:dkey-151j17.4, Drer\lgals9l3, Drer\lgals9l5, Drer\lgals8b, Drer\si:ch211-10a23.2, Drer\lgals8a, Drer\lgalsla, Drer\lgals1l1, Drer\lgalslb, Drer\lgals9l6, Drer\lgals3b, Drer\lgals9l4, Drer\grifin, Drer\lgals3a" - "Cele\lec-12, Cele\lec-9, Cele\lec-8, Cele\lec-10, Cele\lec-11, Cele\T02G6.7, Cele\lec-7, Cele\lec-1, Cele\M6.11, Cele\lec-6, Cele\lec-3" "Xtro\lgals3, Xtro\lgals2, Xtro\LOC100216286, Xtro\lgals9c, Xtro\lgals9b, Xtro\lgals4, Xtro\LOC100496749, Xtro\lgals1, Xtro\lgals9, Xtro\lgalsl, Xtro\lgals8" "Mmus\Lgals2, Mmus\Lgals6, Mmus\Lgals3, Mmus\Lgals12, Mmus\Lgalsl, Mmus\Lgals1, Mmus\Lgals4, Mmus\Lgals9, Mmus\Lgals7, Mmus\Lgals8, Mmus\Grifin" "Hsap\LGALS8, Hsap\LGALS9B, Hsap\LGALS13, Hsap\LGALS9C, Hsap\LGALS7, Hsap\LGALSL, Hsap\OSTC, Hsap\CLC, Hsap\LGALS2, Hsap\LGALS4, Hsap\GRIFIN, Hsap\LGALS12, Hsap\LGALS3, Hsap\LGALS9, Hsap\LGALS1, Hsap\LGALS14, Hsap\LGALS7B" " embryonic stage | stage 13-15 , embryonic stage | stage 8-11 , embryonic stage | stage 8-16 , larval stage , embryonic stage | stage 6,7 , embryonic stage&&larval stage&&adult stage , embryonic stage | stage 13-16 , embryonic stage | early " " embryonic visceral muscle

, embryonic hindgut

, mesoderm

, embryonic central nervous system

, macrophage

, mesoderm anlage

, larval hemocyte

, crystal cell

, embryonic somatic muscle

, lamellocyte

, embryonic foregut

, plasmatocyte

" embryonic stage && larval stage && adult stage FBgn0015773 NetA Netrin-A http://flybase.org/reports/FBgn0015773 "FBtr0073942, FBpp0073759" protein_coding_gene - motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with NetB inferred from genetic interaction with unc-5 glial cell migration ; GO:0008347 | inferred from mutant phenotype regulation of photoreceptor cell axon guidance ; GO:2000289 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from genetic interaction with NetB axon guidance ; GO:0007411 | inferred from sequence or structural similarity proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay "netA, CT27014, CG18657, NetA, netrin A, netrin, net, NetrinA" "IPR018933:Netrin module, non-TIMP type, IPR001134:Netrin domain, IPR002049:Laminin EGF domain, IPR008211:Laminin, N-terminal, IPR008993:Tissue inhibitor of metalloproteinases-like, OB-fold, IPR008979:Galactose-binding domain-like" CG18657 11-Aug-17 DroID_v2017_08 "Drer\LOC567928, Drer\ush2a, Drer\ntng1a, Drer\ntn2, Drer\si:dkey-202e22.2, Drer\lama1, Drer\lama3, Drer\lamc1, Drer\lama5, Drer\egflam, Drer\lama4, Drer\ntng2a, Drer\lamc3, Drer\ntn1b, Drer\ntn5, Drer\ntn1a, Drer\si:dkey-220k22.1, Drer\si:ch211-241e1.3, Drer\si:ch211-158d24.2" - "Cele\unc-6, Cele\lam-3" "Xtro\lama3, Xtro\ntng2, Xtro\lama5, Xtro\ntn3, Xtro\lama4, Xtro\lama1, Xtro\lama2, Xtro\lamc2, Xtro\ntn1, Xtro\ntng1, Xtro\lamc1" "Mmus\Ntng1, Mmus\Lama5, Mmus\Lamc2, Mmus\Ntng2, Mmus\Ntn1, Mmus\Ush2a, Mmus\Lama4, Mmus\Lama1, Mmus\Megf9, Mmus\Ntn5, Mmus\Lama3, Mmus\Egflam, Mmus\Tbc1d24, Mmus\Lama2, Mmus\Lamc1, Mmus\Ntn3, Mmus\Lamc3, Mmus\Ntn4" "Hsap\NTN1, Hsap\NTN5, Hsap\LAMA1, Hsap\LAMA3, Hsap\LAMC2, Hsap\NTNG2, Hsap\LAMA4, Hsap\NTNG1, Hsap\LAMA2, Hsap\USH2A, Hsap\NTN4, Hsap\LAMA5, Hsap\EGFLAM, Hsap\NTN3, Hsap\LAMC1, Hsap\MEGF9, Hsap\LAMC3" " embryonic stage , embryonic stage | stage 12-13 , embryonic stage | stage 12-17 , embryonic stage -- adult stage , embryonic stage | stage 13-17 , embryonic stage | stage 13,14 , embryonic stage | early , embryonic stage | stage 14 " " embryonic neuron

, embryonic nervous system | restricted

, VUM neuron

, midline glial cell

, mesectoderm

, ventral thoracic disc | precursor

, mesoderm anlage

, embryonic brain | restricted

, epidermis | lateral | restricted

, abdominal 2--7 dorsal acute muscle 2

, abdominal 2--7 dorsal acute muscle 1

, visceral mesoderm

, neuroblast MNB

" " embryonic stage | stage >=12 , embryonic stage , embryonic stage | stage 12-17 , embryonic stage | stage 13 , embryonic stage | stage 6 " " visceral mesoderm

, larval muscle system

, neuron &&of embryonic nervous system

, midline glial cell

, ventral furrow

, embryonic/larval tracheal system

, mesectoderm

" "neuroanatomy defective,oxidative stress response defective" "embryonic/larval glial cell,optic lobe,photoreceptor cell R8 stalk,transverse nerve,commissure,axon-537.4,optic nerve,photoreceptor cell & axonGMR.PF,photoreceptor cell & axon,lamina,intersegmental nerve,axonelav.PLu, -537.4" FBgn0005777 PpD3 Protein phosphatase D3 http://flybase.org/reports/FBgn0005777 "FBgn0010250, FBgn0023176, FBgn0037740" protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from electronic annotation with InterPro:IPR011236 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR011236 mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DmPpp5-85E, PP5, CG8402, Pp5-85E, DmPP5, PP5 85E, D3, PpD3" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR011236:Serine/threonine protein phosphatase 5, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR013235:PPP domain, IPR019734:Tetratricopeptide repeat, IPR029052:Metallo-dependent phosphatase-like" CG8402 11-Aug-17 DroID_v2017_08 Drer\ppp5c Scer\PPT1 "Cele\R03D7.8, Cele\pph-5" Xtro\ppp5c Mmus\Ppp5c "Hsap\PPP5D1, Hsap\PPP5C" embryonic stage -- adult stage " embryonic stage , larval stage--adult stage " viable FBgn0004370 Ptp10D Protein tyrosine phosphatase 10D http://flybase.org/reports/FBgn0004370 FBgn0019946 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with protein_id:CAA38066.1 transmembrane receptor protein tyrosine phosphatase activity ; GO:0005001 | inferred from sequence or structural similarity phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay "axon guidance ; GO:0007411 | inferred from genetic interaction with sas inferred from genetic interaction with Ptp69D inferred from physical interaction with sas long-term memory ; GO:0007616 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from genetic interaction with Ptp4E central nervous system development ; GO:0007417 | inferred from genetic interaction with Ptp4E motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Ptp4E, Ptp69D inferred from genetic interaction with Ptp4E, Ptp52F motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Lar inferred from genetic interaction with Lar, Ptp99A inferred from genetic interaction with Ptp69D protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from direct assay inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from direct assay" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity apical part of cell ; GO:0045177 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "DPTP10D, ptp10D, CG1817, PTP10D, Ptp10, CT4920, R-PTP 10D, DPTP, DPTP[[10D]], Ptp10D, dptp, 10D, ptp10d" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR003961:Fibronectin type III, IPR016130:Protein-tyrosine phosphatase, active site, IPR003595:Protein-tyrosine phosphatase, catalytic, IPR029021:Protein-tyrosine phosphatase-like, IPR013783:Immunoglobulin-like fold" CG1817 11-Aug-17 DroID_v2017_08 "Drer\ptprq, Drer\ptprb, Drer\LOC100535694, Drer\ptprz1b, Drer\ptprh, Drer\LOC101885876, Drer\ptprfb, Drer\ptprjb.2, Drer\ptprja, Drer\ptpro, Drer\col7a1l, Drer\ptprjb.1, Drer\slc35c2" "Scer\PTP1, Scer\PTP3, Scer\PTP2" "Cele\ptp-3, Cele\ptp-4, Cele\M05B5.1, Cele\dep-1, Cele\K07F5.6" "Xtro\igdcc4, Xtro\col14a1, Xtro\ptprb, Xtro\ptprq, Xtro\ptpro" "Mmus\Ptprh, Mmus\Ptprj, Mmus\Ptprb, Mmus\Ptprz1, Mmus\Ptprs, Mmus\Ptprd, Mmus\Ptprf, Mmus\Col20a1, Mmus\Ptprc, Mmus\Ptprq, Mmus\Ptpro" "Hsap\PTPRJ, Hsap\PTPRQ, Hsap\PTPRF, Hsap\PTPRH, Hsap\TNXB, Hsap\PTPRD, Hsap\PTPRZ1, Hsap\PTPRB, Hsap\COL20A1, Hsap\PTPRS, Hsap\PTPRO" " embryonic stage , embryonic stage | 9-18hr " embryonic central nervous system | segmentally repeated pattern

" embryonic stage | stage >=12 , embryonic stage , embryonic stage | stage 12-17 , embryonic stage | stage 14-17 , embryonic stage | stage 13-15 " " longitudinal connective

, embryonic/larval salivary gland

, ventral nerve cord | restricted

, embryonic/larval trachea

, ventral nerve cord

, ventral nerve cord commissure

, commissure

" "viable,memory defective,neuroanatomy defective,fertile,partially lethal - majority die,some die during pupal stage,visible" "macrochaeta,intersegmental nerve,anterior fascicle & synapse,embryonic/larval optic neuropil,trichogen cell" FBgn0000658 fj four-jointed http://flybase.org/reports/FBgn0000658 - protein_coding_gene Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt4 protein kinase activity ; GO:0004672 | inferred from direct assay "regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from genetic interaction with Wnt4 cell-cell signaling ; GO:0007267 | inferred from expression pattern inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from mutant phenotype imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype imaginal disc growth ; GO:0007446 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype Wnt signaling pathway, planar cell polarity pathway ; GO:0060071 | inferred from genetic interaction with Wnt4 regulation of protein binding ; GO:0043393 | inferred from direct assay establishment of planar polarity ; GO:0001736 | traceable author statement cell-cell signaling ; GO:0007267 | inferred from sequence or structural similarity inferred from direct assay" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity inferred from direct assay extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000322156 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "CG10917, fj, Fj" IPR024868:Four-jointed box protein 1/four-jointed protein CG10917 11-Aug-17 DroID_v2017_08 Drer\fjx1 - - Xtro\fjx1 Mmus\Fjx1 Hsap\FJX1 " pupal stage , larval stage | third instar " " ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, larval outer optic anlage

, lamina

, eye-antennal disc | gradient

, ventral thoracic disc

, tibia

, dorsal mesothoracic disc

, eye-antennal disc | restricted

" "viable,visible,recessive,cell polarity defective,somatic clone,lethal,dominant,planar polarity defective,cell non-autonomous,cell autonomous,size defective" "wing vein,ectopic,wing,leg,tarsal segment,eye,abdomen,tarsal segment 2,tarsal segment 3,joint,ommatidium,somatic clone,photoreceptor cell R3,photoreceptor cell R4,mesothoracic tergum,coxa,arista,scutellum,third segment of antenna,abdominal tergite 2,metatarsus,cell non-autonomous,tergite,adult cuticle,microchaeta,macrochaeta,wing hair,cell autonomous,abdominal segment 2 & microchaeta,abdominal segment 2 & macrochaeta,distal,embryonic/larval dorsal trunk,trichome & tergite | cell non-autonomous | somatic clone,wing blade,tarsal segment 4,tibia,femur,lens,posterior,crossvein,dorsal,ventral,posterior compartment,anterior crossvein,trichome & tergite | cell non-autonomous | somatic clone‘±Tub84B.PL,eye disc,posterior crossvein,wing vein L4,anterior/posterior compartment boundary" FBgn0000392 cup cup http://flybase.org/reports/FBgn0000392 - protein_coding_gene translation regulator activity ; GO:0045182 | inferred from direct assay RNA binding ; GO:0003723 | inferred from direct assay regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of oskar mRNA translation ; GO:0007319 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from physical interaction with eIF4E1 ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype meiotic chromosome segregation ; GO:0045132 | inferred from direct assay centrosome organization ; GO:0051297 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from genetic interaction with UniProtKB:P25724 negative regulation of oskar mRNA translation ; GO:0007319 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | NOT inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CUP, Cup, fs(2)cup, i239, CG11181, fs(1)cup, cup, DmCup" IPR018862:Eukaryotic translation initiation factor 4E binding protein CG11181 11-Aug-17 DroID_v2017_08 Drer\eif4enif1 - Cele\ifet-1 - Mmus\Eif4enif1 Hsap\EIF4ENIF1 " adult stage && oogenesis stage , adult stage | female && oogenesis stage , oogenesis stage | stage S1-8 , adult stage | male , oogenesis stage && adult stage | female , oogenesis stage | stage S10-14 , embryonic stage | early " " germline stem cell

, germarium

, germarium region 1

, germarium region 3

, cystoblast

, germarium region 2a

, germarium region 2b

, ovary

" " embryonic stage | early , spermatogenesis && adult stage , adult stage && oogenesis stage " " testis

, nurse cell

, oocyte

" "female sterile,recessive,partially,viable" "egg chamber,nurse cell & chromatin,chorion,karyosome,dorsal appendage,egg,maternal effect,cleavage nucleus,ovary,nurse cell,mitosis | ectopic | oogenesis stage S5" FBgn0004514 Oct-TyrR Octopamine-Tyramine receptor http://flybase.org/reports/FBgn0004514 "FBgn0002983, FBgn0004109, FBgn0011463, FBgn0037148" protein_coding_gene octopamine receptor activity ; GO:0004989 | inferred from electronic annotation with InterPro:IPR002002 G-protein coupled amine receptor activity ; GO:0008227 | inferred from direct assay adrenergic receptor activity ; GO:0004935 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity octopamine or tyramine signaling pathway ; GO:0007211 | inferred from direct assay regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010578 | inferred from direct assay cell-cell signaling ; GO:0007267 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway ; GO:1900738 | inferred from direct assay octopamine or tyramine signaling pathway ; GO:0007211 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype octopamine or tyramine signaling pathway ; GO:0007211 | inferred from sequence or structural similarity adenylate cyclase-activating adrenergic receptor signaling pathway ; GO:0071880 | inferred from biological aspect of ancestor with PANTHER:PTN001205212 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with mAChR-A inferred from sequence or structural similarity with HGNC:285 integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with 5-HT7 inferred from sequence or structural similarity with HGNC:5286 "CG7485, OAR_DROME, DmTyrR, OcR, Dmoct/tyr, hono, Ocr, l(3)neo30, TYR, OctyR99AB, OctoR1, OA-R, Tyr-dro, TyR, Tyr, Oct-TyrR, TyrR, DrmOTR, OTR, TAR1, DmTAR1" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR002002:Octopamine receptor, IPR017452:GPCR, rhodopsin-like, 7TM" CG7485 11-Aug-17 DroID_v2017_08 "Drer\adra2b, Drer\htr1d, Drer\htr1ab, Drer\adra2da, Drer\drd2l, Drer\drd2a, Drer\adra2a, Drer\adra2c, Drer\adra2db, Drer\drd2b, Drer\LOC100330650, Drer\htr1aa" - "Cele\tyra-3, Cele\ser-2, Cele\tyra-2" Xtro\htr1d "Mmus\Olfr919, Mmus\Adra2b, Mmus\Adra2a, Mmus\Olfr150, Mmus\Olfr275, Mmus\Olfr1101, Mmus\Adra2c, Mmus\Drd2, Mmus\Htr1a, Mmus\Olfr683, Mmus\Htr1d, Mmus\Olfr684" "Hsap\ADRA2A, Hsap\OR13F1, Hsap\OR56A4, Hsap\ADRA2B, Hsap\OR56A1, Hsap\DRD2, Hsap\HTR1D, Hsap\OR56A5, Hsap\HTR1A, Hsap\ADRA2C, Hsap\OR5T1" adult stage adult head

"neurophysiology defective,smell perception defective,viable,lethal,recessive,fertile" neuromuscular junction DRSC11883 I 1.887743085 0.554246745 0.596165394 -0.245486263 0.401012646 -0.070669498 FBgn0010215 alpha-Cat alpha Catenin http://flybase.org/reports/FBgn0010215 FBan0017947 protein_coding_gene "actin filament binding ; GO:0051015 | inferred from electronic annotation with InterPro:IPR001033, InterPro:IPR006077 cadherin binding ; GO:0045296 | inferred from electronic annotation with InterPro:IPR001033 structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR000633 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P18824-2 actin binding ; GO:0003779 | inferred from sequence or structural similarity" "cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR000633, InterPro:IPR001033, InterPro:IPR006077 adherens junction organization ; GO:0034332 | inferred from mutant phenotype cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype head morphogenesis ; GO:0060323 | inferred from mutant phenotype" actin cytoskeleton ; GO:0015629 | inferred from electronic annotation with InterPro:IPR000633 plasma membrane ; GO:0005886 | inferred from direct assay cell-cell adherens junction ; GO:0005913 | inferred from direct assay adherens junction ; GO:0005912 | non-traceable author statement spot adherens junction ; GO:0005914 | non-traceable author statement catenin complex ; GO:0016342 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay zonula adherens ; GO:0005915 | non-traceable author statement catenin complex ; GO:0016342 | inferred from sequence or structural similarity "alpha-Cat, Dalpha-cat, alphacat, alpha-cat, DalphaC, alpha-ctn, CG17947, a-cat, alpha-CAT, CT39986, Dmcatp, a-Cat, Dalphacat, alphaCat, alpha-catenin, alphaCAT, Dalpha-Cat, LD30423p" "IPR000633:Vinculin, conserved site, IPR001033:Alpha-catenin, IPR006077:Vinculin/alpha-catenin" CG17947 11-Aug-17 DroID_v2017_08 "Drer\ctnna1, Drer\ctnna2, Drer\ctnnal1" - Cele\hmp-1 "Xtro\ctnna1, Xtro\vcl, Xtro\ctnnal1, Xtro\ctnna2" "Mmus\Vcl, Mmus\Ctnna3, Mmus\Ctnna1, Mmus\Ctnna2, Mmus\Gm14025, Mmus\Ctnnal1" "Hsap\CTNNA1, Hsap\CTNNAL1, Hsap\VCL, Hsap\CTNNA2, Hsap\CTNNA3" " larval stage | third instar , embryonic stage && pupal stage && adult stage " organism

" embryonic stage | stage 16 , embryonic stage | stage 11 , larval stage | third instar , embryonic stage | stage >=5 " " embryonic/larval midgut

, ventral midline

, eye disc

, epidermis

, ommatidial precursor cluster

, ventral thoracic disc | restricted

, embryonic/larval foregut

, embryonic peripheral nervous system

, organism

, embryonic/larval salivary gland duct

, morphogenetic furrow |anterior to

ubiquitous , morphogenetic furrow | posterior to | restricted

, embryonic/larval hindgut

, ectoderm

, embryonic central nervous system

" "visible,increased cell number,lethal - all die before end of embryonic stage,cell lethal,somatic clone,cell migration defective,neuroanatomy defective,lethal,partially,lethal - all die before end of pupal stage,some die during pupal stage" "eye | adult stage,inter-ommatidial precursor cell,supernumerary,tertiary pigment cell,embryonic/larval cuticle,cephalopharyngeal skeleton,imaginal disc,somatic clone,ovary,egg chamber,border follicle cell,embryonic head,follicle cell,cone cell,male genitalia,adherens junction | somatic clone,epithelium,female germline cyst" DRSC11917 E 1.409755896 0.530139397 1.997866869 0.017857608 -0.46731122 0.047406125 FBgn0261800 LanB1 LanB1 http://flybase.org/reports/FBgn0261800 protein_coding_gene - substrate adhesion-dependent cell spreading ; GO:0034446 | inferred from direct assay embryonic heart tube morphogenesis ; GO:0003143 | inferred from mutant phenotype basement membrane assembly ; GO:0070831 | inferred from mutant phenotype cardiac muscle cell development ; GO:0055013 | inferred from mutant phenotype animal organ development ; GO:0048513 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from direct assay extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from direct assay basement membrane ; GO:0005604 | inferred from direct assay basement membrane ; GO:0005604 | inferred from sequence or structural similarity basal lamina ; GO:0005605 | inferred from direct assay "LanB, LanB1, Lambeta, CG7123, CT22015, LM-B1/beta, beta1, lamB1, Lam-B1, BcDNA:LD21794, Lan B1, EP-600, LamB1, mspl, laminin" "IPR008979:Galactose-binding domain-like, IPR002049:Laminin EGF domain, IPR008211:Laminin, N-terminal, IPR013015:Laminin IV type B, IPR013032:EGF-like, conserved site, IPR000742:EGF-like domain" CG7123 11-Aug-17 DroID_v2017_08 "Drer\lamb1b, Drer\lamb4, Drer\lamb1a, Drer\lamb2, Drer\si:dkey-220k22.1, Drer\si:dkey-202e22.2, Drer\ush2a, Drer\si:ch1073-15f12.3, Drer\lama4, Drer\si:ch211-158d24.2, Drer\lamb2l" - Cele\lam-1 "Xtro\lamb2, Xtro\lamb3, Xtro\lamb1" "Mmus\Lamb2, Mmus\Megf9, Mmus\Ntn4, Mmus\Lamb1, Mmus\Ush2a, Mmus\Lamb3" "Hsap\USH2A, Hsap\NTN4, Hsap\LAMB3, Hsap\LAMB2, Hsap\LAMB1, Hsap\MEGF9, Hsap\LAMB4" " embryonic stage | late , embryonic stage | stage >12 , embryonic stage | stage 11-12 , embryonic stage " " embryonic/larval midgut

, hemocyte

, head mesoderm

, ventral midline

, embryonic brain

, embryonic/larval fat body

, ventral nerve cord

, visceral mesoderm

, sense organ

, glial cell | lateral

, somatic mesoderm

, ectoderm

, interface glial cell

" " embryonic stage | stage 13-15 , embryonic stage , embryonic stage | 10-13 hr " " segmental nerve

, fat body

, ventral nerve cord

, neuropil associated CNS glial cell

, spiracle

, embryonic/larval midgut

, glial cell

, hemocyte

, embryonic/larval digestive system

, intersegmental nerve

, myoblast &&of larval muscle system

, embryonic somatic muscle

, embryonic brain

, epidermis

" FBgn0011273 Acam Androcam http://flybase.org/reports/FBgn0011273 FBgn0039375 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with Cam myosin VI head/neck binding ; GO:0070855 | inferred from physical interaction with jar actin filament-based movement ; GO:0030048 | inferred by curator from GO:0031476 investment cone ; GO:0070865 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay myosin VI complex ; GO:0031476 | inferred from physical interaction with jar nucleus ; GO:0005634 | inferred from direct assay "Acam, Camr97A, ACaM, CG17769, And, CalB" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG17769 11-Aug-17 DroID_v2017_08 "Drer\efcab6, Drer\cabp1b, Drer\calb2b, Drer\pvalb3, Drer\calm1b, Drer\calml4b, Drer\calb1, Drer\calb2a, Drer\caln2, Drer\calm3b, Drer\tnnc2, Drer\tnnc1a, Drer\pvalb9, Drer\pvalb4, Drer\cabp2a, Drer\calm2b, Drer\calml4a, Drer\cabp5a, Drer\cabp7b, Drer\cabp5b, Drer\si:ch211-197n1.2, Drer\caln1, Drer\calm2a, Drer\tnnc1b, Drer\cabp2b, Drer\scgn, Drer\pvalb6, Drer\efcab2, Drer\pvalb2, Drer\pvalb8, Drer\cabp4, Drer\pvalb1, Drer\cabp1a, Drer\calm3a, Drer\calm1a, Drer\efcab11, Drer\rhbdl3" "Scer\MLC1, Scer\MLC2, Scer\CMD1" "Cele\cal-2, Cele\cal-3, Cele\cal-1, Cele\cmd-1, Cele\cal-4, Cele\tnc-2, Cele\C45G9.7" "Xtro\cabp7, Xtro\tnnc2, Xtro\cabp4, Xtro\calm1, Xtro\scgn, Xtro\LOC548651, Xtro\pgm1, Xtro\ocm.2, Xtro\pvalb.2, Xtro\tnnc1, Xtro\calm2, Xtro\ocm, Xtro\pvalb, Xtro\pvalb.1, Xtro\calb1, Xtro\efcab6, Xtro\calml4" "Mmus\Efcab6, Mmus\Calm5, Mmus\Efcab11, Mmus\Calml3, Mmus\Efcab2, Mmus\Spata21, Mmus\Cabp4, Mmus\Cabp5, Mmus\Cabp2, Mmus\Calm3, Mmus\Calm2, Mmus\Cabp1, Mmus\Tsc1, Mmus\Calb1, Mmus\Calm1, Mmus\Efcab7, Mmus\Pvalb, Mmus\1700023F06Rik, Mmus\Tnnc2, Mmus\Calml4, Mmus\Scgn, Mmus\Rhbdl3, Mmus\Caln1, Mmus\Calm4, Mmus\Cabp7, Mmus\Calb2, Mmus\Efcab9, Mmus\Ocm, Mmus\Tnnc1, Mmus\Efcab3" "Hsap\OCM, Hsap\SPATA21, Hsap\CALN1, Hsap\SCGN, Hsap\TNNC1, Hsap\CALM2, Hsap\CALML6, Hsap\CALML5, Hsap\EFCAB2, Hsap\EFCAB7, Hsap\CALML4, Hsap\EFCAB9, Hsap\CABP1, Hsap\EFCAB6, Hsap\PVALB, Hsap\CALML3, Hsap\CABP2, Hsap\CALM1, Hsap\CALM3, Hsap\TNNC2, Hsap\CALB2, Hsap\EFCAB3, Hsap\EFCAB11, Hsap\OCM2, Hsap\CABP4, Hsap\CALB1, Hsap\CABP7, Hsap\RHBDL3, Hsap\CABP5, Hsap\EFCAB13" viable DRSC24252 K 0.161085217 0.219800005 -0.043283888 -0.097075093 -1.756087972 -0.558742902 FBgn0008635 betaCOP Coat Protein (coatomer) beta http://flybase.org/reports/FBgn0008635 - protein_coding_gene structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR011710 "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR011710, InterPro:IPR016460 regulation of lipid storage ; GO:0010883 | inferred from direct assay intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000067242 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000067242 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000067242 phagocytosis ; GO:0006909 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype" COPI vesicle coat ; GO:0030126 | inferred from biological aspect of ancestor with PANTHER:PTN000067242 Golgi apparatus ; GO:0005794 | inferred from direct assay cis-Golgi network membrane ; GO:0033106 | "COPI, beta-COP, betaCOP, BetaCop, beta-Cop, beta-CopII, BcDNA.GH09317, bcop, betaCop, CG6223, BcDNA:GH09317, Beta Cop, Bcop" "IPR002553:Clathrin/coatomer adaptor, adaptin-like, N-terminal, IPR011710:Coatomer beta subunit, C-terminal, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR016460:Coatomer beta subunit (COPB1), IPR029446:Coatomer beta subunit, appendage platform domain" CG6223 11-Aug-17 DroID_v2017_08 Drer\copb1 Scer\SEC26 "Cele\copb-1, Cele\tag-325, Cele\zyg-1" Xtro\copb1 Mmus\Copb1 Hsap\COPB1 embryonic stage | early "lethal,visible" wing DRSC20312 IEK 0.151197316 2.081650889 2.845743315 -3.858600187 0.26842895 -1.741480973 FBgn0053526 PNUTS PNUTS http://flybase.org/reports/FBgn0053526 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B developmental growth ; GO:0048589 | inferred from mutant phenotype gene expression ; GO:0010467 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR017923 "CG4124, CG31657, PNUTSDm, CG33526, PNUTS, PNUTS-RB, Pnuts" "IPR000571:Zinc finger, CCCH-type, IPR017923:Transcription factor IIS, N-terminal" CG33526 11-Aug-17 DroID_v2017_08 Drer\ppp1r10 - - Xtro\ppp1r10 "Mmus\Prr3, Mmus\Ppp1r10" "Hsap\PRR3, Hsap\PPP1R10" "lethal,lethal - all die before end of larval stage,cell growth defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" "eye,ommatidium" DRSC00638 IE -1.500523695 0.476626738 -0.074073381 -4.21777324 -0.485428196 0.755679097 FBgn0051840 CR31840 - http://flybase.org/reports/FBgn0051840 non_protein_coding_gene - - cellular_component ; GO:0005575 | no biological data available "CG31840, CR31840" - CR31840 11-Aug-17 DroID_v2017_08 - - - - - - "viable,body color defective" mesothoracic tergum DRSC25153 IEK -1.72516516 -0.07896494 -3.486352298 -0.995149178 0.586345853 1.526022371 FBgn0035824 CG8281 - http://flybase.org/reports/FBgn0035824 protein_coding_gene - - - CG8281 IPR006578:MADF domain CG8281 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC10976 E -0.322101669 0.427372901 -1.749474865 0.072530195 0.401121132 -1.073239173 FBgn0266369 Mtp Microsomal triacylglycerol transfer protein http://flybase.org/reports/FBgn0266369 protein_coding_gene phosphatidylcholine transporter activity ; GO:0008525 | inferred from direct assay "lipid transport ; GO:0006869 | inferred from electronic annotation with InterPro:IPR001747, InterPro:IPR011030, InterPro:IPR015816, InterPro:IPR015819 lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype lipoprotein metabolic process ; GO:0042157 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" lipid particle ; GO:0005811 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "Mtp, CG9342, MTP, mtp, CT3751, dMTP, 2L3637, 2L4501" "IPR001747:Lipid transport protein, N-terminal, IPR015816:Vitellinogen, beta-sheet N-terminal, IPR015819:Lipid transport protein, beta-sheet shell, IPR011030:Vitellinogen, superhelical" CG9342 11-Aug-17 DroID_v2017_08 Drer\mtp - Cele\dsc-4 "Xtro\mttp.1, Xtro\mttp.2" Mmus\Mttp Hsap\MTTP DRSC03216 K 0.216683501 -0.142061644 1.07902005 -0.038449183 1.97351512 0.973386424 FBgn0260932 cuff cutoff http://flybase.org/reports/FBgn0260932 protein_coding_gene molecular_function ; GO:0003674 | no biological data available ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype P granule organization ; GO:0030719 | inferred from mutant phenotype germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "cuff, CG13190, Cuff" IPR013961:RAI1-like CG13190 11-Aug-17 DroID_v2017_08 Drer\dxo "Scer\DXO1, Scer\RAI1" "Cele\F07H5.10, Cele\dom-3, Cele\M01G12.14, Cele\C37H5.14, Cele\M01G12.9, Cele\eol-1, Cele\Y47H10A.4, Cele\M01G12.7, Cele\Y47H10A.3, Cele\Y47H10A.5" Xtro\dxo Mmus\Dxo Hsap\DXO DRSC06315 I 1.574092521 0.038776469 0.312761507 0.648358453 -0.827919352 -0.909439978 FBgn0040035 CG40368 - http://flybase.org/reports/FBgn0040035 protein_coding_gene - - - "CG12458, CG40368" - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC20814 I 2.204439971 -1.284546364 0.4780912 -0.71284196 FBgn0037989 ATP8B ATPase 8B http://flybase.org/reports/FBgn0037989 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006539 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR006539 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from sequence or structural similarity with SGD:S000000024 regulation of protein localization ; GO:0032880 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype phospholipid translocation ; GO:0045332 | inferred from sequence or structural similarity with SGD:S000000024 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN001184364 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR006539 integral component of membrane ; GO:0016021 | inferred from sequence model cilium ; GO:0005929 | inferred from direct assay sensory dendrite ; GO:0071683 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN001184364" "CG14741, dATP8B, DmCG14741, ATP8B, atp8b" "IPR001757:P-type ATPase, IPR006539:P-type ATPase, subfamily IV, IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N, IPR032630:P-type ATPase, C-terminal, IPR032631:P-type ATPase, N-terminal" CG14741 11-Aug-17 DroID_v2017_08 "Drer\atp8b5a, Drer\atp8b4, Drer\atp10b, Drer\atp11c, Drer\atp8a1, Drer\atp8b3, Drer\LOC100537096, Drer\atp8b5b, Drer\atp8b2, Drer\atp8a2, Drer\atp11a, Drer\atp8b1" "Scer\DNF1, Scer\DRS2, Scer\DNF2, Scer\DNF3" "Cele\tat-2, Cele\tat-1" "Xtro\atp10a, Xtro\atp8b4, Xtro\atp11c, Xtro\atp10d, Xtro\atp8b3, Xtro\atp11b, Xtro\atp8b1, Xtro\atp11a, Xtro\LOC100490503" "Mmus\Atp8b3, Mmus\Atp11c, Mmus\Atp8b2, Mmus\Atp8a1, Mmus\Atp8a2, Mmus\Atp8b1, Mmus\Atp10a, Mmus\Atp8b4, Mmus\Atp8b5, Mmus\Atp11a, Mmus\Atp11b, Mmus\Atp10b" "Hsap\ATP11C, Hsap\ATP11A, Hsap\ATP8B2, Hsap\ATP8B4, Hsap\ATP8B1, Hsap\ATP8B3, Hsap\ATP8A2, Hsap\ATP11B, Hsap\ATP10A, Hsap\ATP10D, Hsap\ATP10B, Hsap\ATP8A1" "viable,neurophysiology defective,smell perception defective,fertile" antennal olfactory receptor neuron DRSC14961 K 0.014231814 -0.105551607 0.585168408 0.252171967 0.408243588 1.804688201 FBgn0001226 Hsp27 Heat shock protein 27 http://flybase.org/reports/FBgn0001226 "FBgn0010232, FBgn0044559" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with lwr unfolded protein binding ; GO:0051082 | inferred from sequence model unfolded protein binding ; GO:0051082 | inferred from direct assay defense response to bacterium ; GO:0042742 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay behavioral response to starvation ; GO:0042595 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model response to heat ; GO:0009408 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype protein refolding ; GO:0042026 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Dmel23.6, hsp27, Hsp28, HSP28, 27K, DmHsp27, hsp-27, HSP27, hsp28, Dhsp27, hsp26, hsp27/26, 28, hsp 27, CG4466, anon-WO0140519.69, Hsp27, small hsp locus 67B, DmHSP27, 27, Hsp 27" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4466 11-Aug-17 DroID_v2017_08 "Drer\hspb6, Drer\hspb12, Drer\hspb3, Drer\hspb9, Drer\cryaa, Drer\hspb8, Drer\hspb2, Drer\si:dkey-1k23.3, Drer\hspb1, Drer\cryaba, Drer\hspb11, Drer\hspb15, Drer\hspb7" - "Cele\hsp-12.2, Cele\sip-1, Cele\F08H9.3, Cele\hsp-16.49, Cele\hsp-16.48, Cele\hsp-16.1, Cele\ZK1128.7, Cele\hsp-12.1, Cele\Y55F3BR.6, Cele\hsp-16.41, Cele\hsp-43, Cele\hsp-16.2, Cele\hsp-16.11, Cele\hsp-17, Cele\hsp-12.3, Cele\F08H9.4, Cele\hsp-12.6" "Xtro\hspb2, Xtro\cryaa, Xtro\hspb6, Xtro\uqcrh, Xtro\hspb1, Xtro\hspb8, Xtro\hsp30d, Xtro\hspb3, Xtro\cryab, Xtro\hsp30e" "Mmus\Cryab, Mmus\Hspb2, Mmus\Hspb9, Mmus\Hspb1, Mmus\Hspb7, Mmus\Hspb6, Mmus\Cryaa, Mmus\Hspb3, Mmus\Hspb8" "Hsap\HSPB3, Hsap\HSPB9, Hsap\HSPB8, Hsap\HSPB7, Hsap\HSPB6, Hsap\CRYAB, Hsap\CRYAA, Hsap\HSPB2, Hsap\HSPB1, Hsap\LOC102724652" " prepupal stage , embryonic stage | <=2-3 hr , larval stage | late third instar larval stage " organism

" larval stage | first instar , embryonic stage , pupal stage " "viable,fertile,starvation stress response defective,short lived,immune response defective,long lived,male,chemical resistant,female fertile,reduced,visible" trichogen cell DRSC26877 K -0.0594911 0.495705638 0.817929218 0.127726523 -0.086521502 -1.563939182 FBgn0001137 grk gurken http://flybase.org/reports/FBgn0001137 - protein_coding_gene epidermal growth factor receptor binding ; GO:0005154 | non-traceable author statement epidermal growth factor receptor binding ; GO:0005154 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P49858 "dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | traceable author statement anterior/posterior pattern specification ; GO:0009952 | traceable author statement oocyte dorsal/ventral axis specification ; GO:0007310 | non-traceable author statement oocyte axis specification ; GO:0007309 | traceable author statement maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded ; GO:0008070 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype cell fate specification ; GO:0001708 | traceable author statement epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Cbl gurken signaling pathway ; GO:0008314 | traceable author statement border follicle cell migration ; GO:0007298 | inferred from mutant phenotype oocyte anterior/posterior axis specification ; GO:0007314 | traceable author statement dorsal appendage formation ; GO:0046843 | non-traceable author statement oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification ; GO:0030722 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | traceable author statement dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | non-traceable author statement cell fate determination ; GO:0001709 | traceable author statement border follicle cell migration ; GO:0007298 | traceable author statement chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype oocyte axis specification ; GO:0007309 | non-traceable author statement cargo loading into COPII-coated vesicle ; GO:0090110 | inferred from mutant phenotype anterior/posterior axis specification, follicular epithelium ; GO:0030714 | traceable author statement embryonic axis specification ; GO:0000578 | traceable author statement oocyte anterior/posterior axis specification ; GO:0007314 | non-traceable author statement anterior/posterior axis specification, follicular epithelium ; GO:0030714 | non-traceable author statement" plasma membrane ; GO:0005886 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement endoplasmic reticulum ; GO:0005783 | traceable author statement extracellular region ; GO:0005576 | inferred from biological aspect of ancestor with PANTHER:PTN000960795 "grk, Grk, CG17610, CT32746, GRK, s-Grk" "IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site" CG17610 11-Aug-17 DroID_v2017_08 Drer\nrg1 - - - Mmus\Nrg1 Hsap\NRG1 ", adult stage && oogenesis stage | stage S1-7 , adult stage | female , oogenesis stage | stage >S8 , adult stage && oogenesis stage | stage >S8 " " stage S9 oocyte && stage S10 oocyte

anterior & dorsal , nurse cell

, stage S8 oocyte | anterior

, stage S8 oocyte

anterior , stage S6 oocyte

posterior , oocyte | anterior

{ 0 Egfr* } , oocyte | dorsal <&> anterior

, oocyte | dorsal <&> anterior

{ + fs(1)K10* } , oocyte | anterior

{ + capu* } , oocyte | dorsal <&> anterior

{ 0 cni* } , stage S9 oocyte | anterior & dorsal

, oocyte | anterior

{ + spir* } , oocyte | anterior

{ + sqd* } " " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S8 , adult stage && oogenesis stage | stage , oocyte | restricted

, oocyte

, stage S10 oocyte

anterior & dorsal , germarium region 2b

" "female sterile,lethal,maternal effect,recessive,viable,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,visible" "ventral furrow,supernumerary,ectopic,embryonic/first instar larval cuticle,follicle cell,embryo,ventral,dorsal appendage,egg operculum,maternal effect,egg,egg chamber,chorion,oocyte,female germline cyst,oocyte nucleus,vitelline membrane,cold sensitive,micropyle,germline clone,microtubule & oocyte,border follicle cell,ovary,oocyte & microtubule,pericentriolar material & oocyte | posterior,wing vein,wing,wing vein L4" FBgn0005696 DNApol-alpha73 DNA polymerase alpha 73kD http://flybase.org/reports/FBgn0005696 - protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007185 DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity protein heterodimerization activity ; GO:0046982 | inferred from biological aspect of ancestor with PANTHER:PTN000551732 DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity with UniProtKB:P38121 DNA replication initiation ; GO:0006270 | inferred from biological aspect of ancestor with PANTHER:PTN000551732 DNA-dependent DNA replication ; GO:0006261 | inferred from sequence or structural similarity DNA replication initiation ; GO:0006270 | inferred from sequence or structural similarity with UniProtKB:P38121 alpha DNA polymerase:primase complex ; GO:0005658 | inferred from biological aspect of ancestor with PANTHER:PTN000551732 alpha DNA polymerase:primase complex ; GO:0005658 | inferred from sequence or structural similarity with UniProtKB:P38121 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P38121 alpha DNA polymerase:primase complex ; GO:0005658 | inferred from sequence or structural similarity nuclear envelope ; GO:0005635 | inferred from sequence or structural similarity with UniProtKB:P38121 "Dmpol alpha, CG5923, pol alpha, DNA polalpha, Polalpha, polalpha, POLA, DNApol-alpha72, DNApolalpha, DNApol-alpha, DNApol-alpha73, Pol, DNA pol-73, DNA polymerase alpha 73 kD, Polalpha 73kDa" "IPR007185:DNA polymerase alpha/epsilon, subunit B, IPR016722:DNA polymerase alpha, subunit B, IPR013627:DNA polymerase alpha, subunit B N-terminal" CG5923 11-Aug-17 DroID_v2017_08 Drer\pola2 Scer\POL12 Cele\div-1 Xtro\pola2 Mmus\Pola2 Hsap\POLA2 egg stage | fertilized egg " female pronucleus

, male pronucleus

" visible eye FBgn0020381 Dredd Death related ced-3/Nedd2-like caspase http://flybase.org/reports/FBgn0020381 "FBgn0013388, FBgn0023366, FBgn0024454, FBtr0070152, FBpp0070147, FBtr0070153, FBpp0070148, FBtr0070154, FBpp0070149" protein_coding_gene cysteine-type endopeptidase activator activity involved in apoptotic process ; GO:0008656 | inferred from mutant phenotype cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement endopeptidase activity ; GO:0004175 | inferred from direct assay cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:0097200 | inferred from biological aspect of ancestor with PANTHER:PTN000825206 protein binding ; GO:0005515 | inferred from physical interaction with Fadd protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q94527 peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype apoptotic process ; GO:0006915 | traceable author statement innate immune response ; GO:0045087 | traceable author statement negative regulation of programmed cell death ; GO:0043069 | inferred from mutant phenotype protein processing ; GO:0016485 | inferred from direct assay defense response ; GO:0006952 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype execution phase of apoptosis ; GO:0097194 | inferred from biological aspect of ancestor with PANTHER:PTN000825206 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype apoptotic process ; GO:0006915 | non-traceable author statement positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | traceable author statement peripheral nervous system neuron development ; GO:0048935 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement immune response ; GO:0006955 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay "Dredd, DREDD, dredd, Dcp-2/Dredd, Dcp-2, CG7486, EG:115C2.9, DCP-2/DREDD, DCP-2, dcp-2/dredd, Dcp2, DCP2, anon-1BCa, Redd, Dedd, Dredd/DCP-2, dDredd, CASP8_DROME" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR015917:Peptidase C14A, caspase catalytic domain, IPR029030:Caspase-like domain" CG7486 11-Aug-17 DroID_v2017_08 "Drer\caspxa, Drer\LOC798445, Drer\casp8, Drer\LOC100331324, Drer\caspb, Drer\si:ch211-195h23.3, Drer\pea15, Drer\cflara, Drer\caspa, Drer\si:dkey-103e21.5, Drer\casp9, Drer\casp7, Drer\LOC101886133, Drer\si:dkey-10c21.1, Drer\casp8l1, Drer\caspbl, Drer\casp8l2, Drer\zgc:171731, Drer\zgc:194469, Drer\casp3b, Drer\casp3a, Drer\casp6, Drer\gbp3, Drer\casp2" - "Cele\ced-3, Cele\csp-1" "Xtro\LOC733553, Xtro\casp3, Xtro\pea15, Xtro\casp10, Xtro\casp7, Xtro\casp2, Xtro\casp9, Xtro\casp1, Xtro\casp6" "Mmus\Casp9, Mmus\Casp4, Mmus\Casp7, Mmus\Casp12, Mmus\Pea15a, Mmus\Casp2, Mmus\Casp8, Mmus\Casp1, Mmus\Casp14, Mmus\Casp3, Mmus\Casp6, Mmus\Cflar" "Hsap\CASP10, Hsap\CARD17, Hsap\CASP1, Hsap\PEA15, Hsap\CARD8, Hsap\CASP9, Hsap\CARD18, Hsap\CASP7, Hsap\CARD16, Hsap\CFLAR, Hsap\CASP6, Hsap\CASP2, Hsap\CASP8, Hsap\CASP5, Hsap\CASP3, Hsap\CASP14, Hsap\CASP4" " embryonic stage | stage 11 , adult stage && oogenesis stage | stage S10 , adult stage , adult stage && oogenesis stage | stage S10-13 , embryonic stage , embryonic stage | stage <=10 , embryonic stage | stage 13 , embryonic stage | stage 16 " " embryonic gnathal segment | restricted

, oocyte

, embryonic labral segment | restricted

, nurse cell

,

ubiquitous , dorsal ridge

, embryonic central nervous system

, ventral nerve cord

" "viable,fertile,visible,dominant,immune response defective,wild-type,oxidative stress response defective,recessive,increased cell death,conditional,radiation resistant,decreased cell death,neuroanatomy defective" "mesothoracic tergum,macrochaeta,ectopic,spermatid,intestinal stem cell,peptidergic neuron" DRSC18461 E 0.060605026 -0.476640838 -1.50298327 0.303757827 0.553468834 0.759500968 FBgn0028675 Sur Sulfonylurea receptor http://flybase.org/reports/FBgn0028675 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" response to hypoxia ; GO:0001666 | inferred from mutant phenotype transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 heart development ; GO:0007507 | non-traceable author statement chitin biosynthetic process ; GO:0006031 | NOT inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "Dme_CG5772, dSUR, CG5772, sur, Dsur, SUR, CK00325, BEST:CK00325, Sur, dsur, dSur, CYO, cyo" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5772 11-Aug-17 DroID_v2017_08 "Drer\LOC100329706, Drer\abcc4, Drer\abcc9, Drer\abcc5, Drer\abcc12, Drer\abcc10, Drer\cftr, Drer\abcc6b.2, Drer\abcc6a, Drer\abcc13, Drer\abcc8, Drer\abcc1" "Scer\YBT1, Scer\YOR1, Scer\VMR1, Scer\YCF1, Scer\BPT1, Scer\YKR104W, Scer\NFT1" - "Xtro\abcc4, Xtro\cftr, Xtro\abcc3, Xtro\abcc6, Xtro\abcc1, Xtro\abcc10, Xtro\LOC101733439" "Mmus\Abcc8, Mmus\Abcc12, Mmus\Abcc3, Mmus\Abcc10, Mmus\Abcc1, Mmus\Abcc5, Mmus\Abcc4, Mmus\Cftr, Mmus\Abcc9, Mmus\Abcc6, Mmus\Abcc2" "Hsap\ABCC2, Hsap\ABCC3, Hsap\CFTR, Hsap\ABCC9, Hsap\ABCC1, Hsap\ABCC5, Hsap\ABCC4, Hsap\ABCC11, Hsap\ABCC6, Hsap\ABCC12, Hsap\ABCC8, Hsap\ABCC10" " embryonic stage | stage >=10 , embryonic stage | stage >=15 , adult stage , embryonic stage | early , larval stage " " embryonic/larval dorsal vessel

, embryonic/larval salivary gland

, embryonic/larval posterior spiracle

, embryonic/larval tracheal system

" "stress response defective,viable,immune response defective" adult heart FBgn0008651 lbl ladybird late http://flybase.org/reports/FBgn0008651 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "central nervous system development ; GO:0007417 | non-traceable author statement regulation of cell fate specification ; GO:0042659 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement genital disc morphogenesis ; GO:0007483 | inferred from mutant phenotype epidermis development ; GO:0008544 | inferred from mutant phenotype muscle organ development ; GO:0007517 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from genetic interaction with lbe myoblast fusion ; GO:0007520 | inferred from genetic interaction with lbe cell migration ; GO:0016477 | inferred from genetic interaction with lbe regulation of neuron differentiation ; GO:0045664 | inferred from mutant phenotype mesodermal cell fate specification ; GO:0007501 | traceable author statement myoblast proliferation ; GO:0051450 | inferred from genetic interaction with lbe skeletal muscle tissue development ; GO:0007519 | inferred from genetic interaction with lbe" nucleus ; GO:0005634 | inferred from direct assay "CG6570, lb, Lb, nkch4, NKch4, NK?, lbl, Lbl" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR000047:Helix-turn-helix motif" CG6570 11-Aug-17 DroID_v2017_08 "Drer\tlx3b, Drer\pnx, Drer\tlx1, Drer\lbx2, Drer\barx2, Drer\LOC100008066, Drer\barhl2, Drer\lbx1b, Drer\lbx1a, Drer\hlx1, Drer\nkx1.2lb, Drer\dbx1b, Drer\ved, Drer\barhl1b, Drer\tlx2, Drer\vox, Drer\barx1" - Cele\lim-7 "Xtro\tlx3, Xtro\nkx1-2, Xtro\barx1, Xtro\ventx1.2, Xtro\lbx1, Xtro\dbx1, Xtro\barhl2, Xtro\barhl1, Xtro\tlx1, Xtro\tlx2, Xtro\nkx1-1, Xtro\hlx" "Mmus\Dbx1, Mmus\Barhl2, Mmus\Barhl1, Mmus\Nkx1-2, Mmus\Dbx2, Mmus\Nkx1-1, Mmus\Hlx, Mmus\Barx1, Mmus\Tlx2, Mmus\Tlx1, Mmus\Lbx2, Mmus\Lbx1, Mmus\Tlx3, Mmus\Barx2" "Hsap\TLX1, Hsap\BARHL1, Hsap\HOXB9, Hsap\HOXD9, Hsap\HOXC10, Hsap\DBX2, Hsap\LBX2, Hsap\HOXC5, Hsap\NKX1-1, Hsap\HOXB7, Hsap\LBX1, Hsap\HOXA9, Hsap\BARX2, Hsap\DBX1, Hsap\HOXC9, Hsap\HLX, Hsap\TLX3, Hsap\BARX1, Hsap\BARHL2, Hsap\TLX2" " embryonic stage | stage 10-13 , embryonic stage | late , larval stage | third instar , embryonic stage | stage 13 , embryonic stage | stage >10 , embryonic stage | stage 15 , embryonic stage | stage 13-17 , pupal stage , embryonic stage | 8-20 hr " " dorsal ectoderm &&of abdominal segment 1--7

, central nervous system | restricted

, epidermis | segmentally repeated

, anal pad

, epidermis | dorsal

, ventral nerve cord

, ectoderm | ventral

, segment border muscle

, embryonic peripheral nervous system | restricted

, embryonic central nervous system | restricted

" " embryonic stage | stage 10-13 , embryonic stage | late , embryonic stage | stage 15 , embryonic stage | stage 13 , embryonic stage | stage >10 " " dorsal ectoderm &&of abdominal segment 1--7

, central nervous system | restricted

, epidermis | dorsal

, embryonic peripheral nervous system | restricted

, ectoderm | ventral

, segment border muscle

, anal pad

" "viable,fertile" "embryonic/larval dorsal vessel,precursor,dorsal denticle,EL neuron,central nervous system,exit glial cell,ectopic,glial cell,intersegmental nerve,prothoracic segmental nerve" FBgn0031877 CG10399 - http://flybase.org/reports/FBgn0031877 protein_coding_gene hydroxymethylglutaryl-CoA lyase activity ; GO:0004419 | inferred from sequence or structural similarity with UniProtKB:P35914 leucine metabolic process ; GO:0006551 | inferred from sequence or structural similarity with UniProtKB:P35914 microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P35914 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:5005 "145934_at, CG10399" "IPR000891:Pyruvate carboxyltransferase, IPR013785:Aldolase-type TIM barrel" CG10399 11-Aug-17 DroID_v2017_08 "Drer\hmgcll1, Drer\hmgcl" "Scer\LYS21, Scer\LYS20" Cele\Y71G12B.10 "Xtro\c9orf3, Xtro\hmgcll1, Xtro\hmgcl" "Mmus\Hmgcl, Mmus\Hmgcll1" "Hsap\HMGCL, Hsap\HMGCLL1" "partially lethal - majority die,some die during pupal stage" DRSC02051 K 1.05765146 0.186094507 -0.04194903 0.312547875 2.137781602 0.523380965 FBgn0259221 CG42321 - http://flybase.org/reports/FBgn0259221 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006539 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR006539 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from sequence or structural similarity with SGD:S000000024 phospholipid translocation ; GO:0045332 | inferred from sequence or structural similarity with SGD:S000000024 Golgi vesicle budding ; GO:0048194 | inferred from biological aspect of ancestor with PANTHER:PTN001533679 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR006539 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN001533679 integral component of membrane ; GO:0016021 | inferred from sequence model" "CG42321, anon-WO0153538.54, CG17034, CG30061, DmCG42321" "IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site, IPR001757:P-type ATPase, IPR006539:P-type ATPase, subfamily IV, IPR023298:P-type ATPase, transmembrane domain, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N, IPR032630:P-type ATPase, C-terminal, IPR032631:P-type ATPase, N-terminal" CG42321 11-Aug-17 DroID_v2017_08 "Drer\atp8b5a, Drer\atp8b5b, Drer\atp10b, Drer\atp8a1, Drer\atp8a2, Drer\atp11a, Drer\atp8b4, Drer\atp8b3, Drer\atp10d, Drer\atp11c, Drer\atp8b1, Drer\atp10a" "Scer\DRS2, Scer\DNF3, Scer\DNF2, Scer\DNF1" "Cele\tat-3, Cele\tat-4, Cele\tat-2, Cele\tat-1" "Xtro\LOC100490503, Xtro\atp10d, Xtro\atp10a, Xtro\atp8b3, Xtro\atp8b1, Xtro\atp8a1, Xtro\atp8b4" "Mmus\Atp11c, Mmus\Atp10a, Mmus\Atp8b1, Mmus\Atp11b, Mmus\Atp10b, Mmus\Atp8b4, Mmus\Atp8a1, Mmus\Atp8b5, Mmus\Atp8b3, Mmus\Atp8b2, Mmus\Atp8a2, Mmus\Atp11a" "Hsap\ATP8B3, Hsap\ATP8B1, Hsap\ATP8A2, Hsap\ATP8B2, Hsap\ATP10A, Hsap\ATP11C, Hsap\ATP10B, Hsap\ATP8B4, Hsap\ATP8A1, Hsap\ATP11A, Hsap\ATP11B, Hsap\ATP10D" DRSC05421 I 1.524030485 -0.327715361 0.426227973 0.527593874 0.256137851 0.418987414 FBgn0050273 CG30273 - http://flybase.org/reports/FBgn0050273 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13515, CG30273" IPR006629:LPS-induced tumour necrosis factor alpha factor CG30273 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-157c3.4, Drer\litaf, Drer\si:ch211-202h22.7, Drer\si:ch211-202h22.8, Drer\si:ch211-202h22.9, Drer\si:dkeyp-75b4.8, Drer\cdip1" - "Cele\C08E8.1, Cele\Y37D8A.26, Cele\F36G3.3, Cele\B0348.2, Cele\Y37D8A.6, Cele\Y87G2A.18, Cele\Y37D8A.8, Cele\F16F9.1, Cele\Y40H7A.11, Cele\Y22D7AL.15, Cele\Y87G2A.19, Cele\B0348.1" Xtro\litaf "Mmus\Litaf, Mmus\Cdip1" "Hsap\CDIP1, Hsap\LITAF" viable DRSC22059 I -0.786782566 1.846904577 -0.150942939 0.415192302 1.393556446 0.764823363 FBgn0039452 CG14245 - http://flybase.org/reports/FBgn0039452 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG14245, CG32950" IPR002557:Chitin binding domain CG14245 11-Aug-17 DroID_v2017_08 - - - - - - DRSC14741 I -1.613390109 0.669816434 -0.42018715 0.441402157 -0.592142559 0.39287273 FBgn0052660 CR32660 - http://flybase.org/reports/FBgn0052660 non_protein_coding_gene - - - CR32660 - CR32660 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile" DRSC18942 I -0.643244641 1.511600444 0.192506079 -0.046128039 0.224810805 -0.265033448 FBgn0011754 PhKgamma Phosphorylase kinase gamma http://flybase.org/reports/FBgn0011754 FBgn0044448 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR002291, InterPro:IPR017441 calmodulin binding ; GO:0005516 | inferred from electronic annotation with InterPro:IPR002291 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement phosphorylase kinase activity ; GO:0004689 | inferred from sequence or structural similarity phosphorylase kinase activity ; GO:0004689 | inferred from biological aspect of ancestor with PANTHER:PTN001552730" glycogen biosynthetic process ; GO:0005978 | inferred from electronic annotation with InterPro:IPR002291 peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 glucose catabolic process ; GO:0006007 | inferred from sequence or structural similarity embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 glycogen metabolic process ; GO:0005977 | inferred from biological aspect of ancestor with PANTHER:PTN001552730 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity phosphorylase kinase complex ; GO:0005964 | inferred from sequence or structural similarity phosphorylase kinase complex ; GO:0005964 | inferred from biological aspect of ancestor with PANTHER:PTN001552730 "CG1830, DPhK-gamma, anon-sts6, ESTS:194B3T, EP779, PhKgamma, Phkgamma, PhKg" "IPR000719:Protein kinase domain, IPR002291:Phosphorylase kinase, gamma catalytic subunit, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG1830 11-Aug-17 DroID_v2017_08 "Drer\mylk4a, Drer\mylk3, Drer\phkg1b, Drer\phkg2, Drer\phkg1a" "Scer\DUN1, Scer\MEK1" "Cele\Y50D7A.3, Cele\ZC373.4, Cele\K02E10.7" "Xtro\phkg2, Xtro\phkg1" "Mmus\Phkg2, Mmus\Mylk3, Mmus\Phkg1" "Hsap\MYLK3, Hsap\PHKG1, Hsap\PHKG2" "viable,fertile,paralytic,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "femur,joint,tibia,cuticle,leg" DRSC20268 K -0.166140575 0.426037955 -0.187649355 -0.154747289 -0.074065569 -1.592921127 FBgn0260639 gammaTub23C gamma-Tubulin at 23C http://flybase.org/reports/FBgn0260639 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity GTP binding ; GO:0005525 | inferred from direct assay guanyl nucleotide binding ; GO:0019001 | inferred from direct assay microtubule minus-end binding ; GO:0051011 | contributes_to inferred from direct assay" cytoplasmic microtubule organization ; GO:0031122 | inferred from electronic annotation with InterPro:IPR002454 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype microtubule nucleation ; GO:0007020 | inferred from direct assay mitotic sister chromatid separation ; GO:0051306 | inferred from direct assay microtubule nucleation ; GO:0007020 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype centriole-centriole cohesion ; GO:0010457 | inferred from direct assay gamma-tubulin ring complex ; GO:0008274 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay gamma-tubulin small complex ; GO:0008275 | inferred from physical interaction with Grip91 inferred from physical interaction with Grip84 gamma-tubulin complex ; GO:0000930 | inferred from physical interaction with Grip163 inferred from physical interaction with Grip128 cytoplasm ; GO:0005737 | inferred from direct assay microtubule ; GO:0005874 | inferred from sequence or structural similarity pericentriolar material ; GO:0000242 | inferred from direct assay gamma-tubulin large complex ; GO:0000931 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay "gamma-Tub, Tub23, CG3157, gamma-Tub23C, gammaTub, gammaTub23C, l(2)23Ce, gamma-tub, gamma-tubulin, GTU88*, gamma tubulin, gammatub, g-Tubulin, gammaTUB, gamma-tub23, GAMMA23C, D.m.GAMMA-23C, GTUB, gammaTUB23C, gammatub23C, gamma[zy], gammaTub23CD, CG 3157, gamma-tub 23C, gamma-tub23C, Tub3A, gTub23C, tubulin" "IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain, IPR000217:Tubulin, IPR002454:Gamma tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal" CG3157 11-Aug-17 DroID_v2017_08 "Drer\tubg1, Drer\tubd1" Scer\TUB4 Cele\tbg-1 "Xtro\tubg1, Xtro\tubz1, Xtro\tubd1" "Mmus\Tubg2, Mmus\Tubd1, Mmus\Tubg1" "Hsap\TUBG2, Hsap\TUBD1, Hsap\TUBG1" DRSC00820 I 1.847910477 -0.102000106 -0.65449196 -0.05343407 -0.863022883 0.030575329 FBgn0261648 salm spalt major http://flybase.org/reports/FBgn0261648 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000579295" "glial cell development ; GO:0021782 | inferred from mutant phenotype R8 cell differentiation ; GO:0045465 | non-traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 open tracheal system development ; GO:0007424 | traceable author statement compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype male gonad development ; GO:0008584 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype antennal joint development ; GO:0048098 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype male genitalia development ; GO:0030539 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype regulation of cell fate specification ; GO:0042659 | inferred from mutant phenotype notum cell fate specification ; GO:0035310 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement oenocyte development ; GO:0007438 | inferred from mutant phenotype R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement sensory perception of sound ; GO:0007605 | inferred from genetic interaction with salr R8 cell differentiation ; GO:0045465 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "salm, Sal, CG6464, sal, spalt, Spalt, salM, salII, SalM, SPALT, l(2)03602, 3602, SAL, Salm, slam, B1164, SALM, spalt major" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG6464 11-Aug-17 DroID_v2017_08 "Drer\sall3b, Drer\znf1010, Drer\sall4, Drer\sall3a, Drer\sall2, Drer\yy1b, Drer\si:ch211-212k18.5, Drer\znf367, Drer\znf526, Drer\sall1a, Drer\znf983, Drer\sall1b, Drer\yy1a" Scer\CMR3 Cele\sem-4 "Xtro\sall1, Xtro\sall2, Xtro\sall4, Xtro\sall3" "Mmus\Sall3, Mmus\Sall4, Mmus\Zfp236, Mmus\Gm14124, Mmus\Zfp62, Mmus\Zfp26, Mmus\Zfp367, Mmus\Zfp658, Mmus\Sall2, Mmus\Zfp619, Mmus\Sall1, Mmus\Yy1" "Hsap\ZNF658, Hsap\ZNF536, Hsap\ZNF208, Hsap\ZFP62, Hsap\SALL3, Hsap\ZNF227, Hsap\ZNF761, Hsap\SALL4, Hsap\ZNF91, Hsap\ZNF546, Hsap\ZNF721, Hsap\SALL1, Hsap\ZNF236, Hsap\ZNF808, Hsap\ZNF226, Hsap\ZNF107, Hsap\ZNF268, Hsap\YY1, Hsap\SALL2, Hsap\ZNF367" " embryonic stage | stage 5 , embryonic stage | stage 13 , embryonic stage | 1-12 hr , larval stage | third instar , embryonic stage | gastrula , embryonic stage | stage >15 , embryonic stage | embryonic cycle 14 , embryonic stage | stage >=13 " " organism | 10-20% egg length

, embryonic/larval hindgut

, dorsal mesothoracic disc | restricted

, cephalic furrow | posterior

, eye-antennal disc | primordium

, organism | 80% egg length

, genital disc | primordium

, organism | 80-90% egg length

, organism | 60-70% egg length

, organism | 0-20% egg length

, organism | ventro-lateral

, cuticle | primordium & segmentally repeated " " larval stage | third instar , embryonic stage | stage 15-17 , embryonic stage | stage 11 , embryonic stage | stage 16 , embryonic stage | stage 5 , embryonic stage | stage 4 | late , embryonic stage | stage 12 " " dorsal mesothoracic disc | restricted

, embryonic central nervous system

, parasegment 1--3

, embryonic/larval posterior spiracle

, parasegment 14,15

, organism | 60-70% egg length

, ventral neurogenic region

, dorsal mesothoracic disc | dorsal comparment & medial

,

~60-70% egg length , posterior spiracle primordium

, organism | 10-20% egg length

, embryonic/larval tracheal system

, organism | 80-90% egg length

" FBgn0086906 sls sallimus http://flybase.org/reports/FBgn0086906 protein_coding_gene actin binding ; GO:0003779 | inferred from direct assay actin binding ; GO:0003779 | inferred from mutant phenotype structural constituent of muscle ; GO:0008307 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with Msp300 muscle organ development ; GO:0007517 | traceable author statement myoblast fusion ; GO:0007520 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern sarcomere organization ; GO:0045214 | inferred from genetic interaction with Mlp84B somatic muscle development ; GO:0007525 | inferred from expression pattern muscle attachment ; GO:0016203 | inferred from mutant phenotype skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from direct assay visceral muscle development ; GO:0007522 | inferred from expression pattern Z disc ; GO:0030018 | inferred from mutant phenotype Z disc ; GO:0030018 | inferred from direct assay I band ; GO:0031674 | inferred from direct assay sarcomere ; GO:0030017 | inferred from direct assay striated muscle myosin thick filament ; GO:0005863 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay condensed nuclear chromosome ; GO:0000794 | inferred from direct assay "Ket, CG18242, Titin, CG1915, sal, D-titin, titin, CT41299, l(3)dre8, l(3)rL182, l(3)j1D7, sam, l(3)62Ca, l(3)Ca, l(3)S002001, 0020/01, anon-CREST, MCP, CG18857, CG18245, sls, ket, Sls, D-Titin, KZ, SLS, d-titin, kettin, TITIN" "IPR001452:SH3 domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR010939:Protein of unknown function DUF1136, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG1915 11-Aug-17 DroID_v2017_08 "Drer\obsl1b, Drer\igfn1.2, Drer\spegb, Drer\LOC101885775, Drer\si:dkey-10h3.1, Drer\LOC101884775, Drer\ncam3, Drer\vwa10.1, Drer\mylka, Drer\obsl1a, Drer\sc:d0284, Drer\mylkb, Drer\LOC100148735, Drer\LOC100333244, Drer\vwa11, Drer\LOC100535144, Drer\zmp:0000001289, Drer\si:ch211-1f22.3, Drer\zgc:172106, Drer\si:ch211-171h4.5, Drer\spega, Drer\egflam, Drer\myom1a, Drer\si:ch211-286b5.9, Drer\LOC100333105, Drer\vwa7, Drer\scospondin, Drer\obscnb, Drer\alpk3b, Drer\cd22, Drer\myom3, Drer\hmcn2, Drer\igfn1.4, Drer\vwa10.2, Drer\LOC100006752, Drer\si:ch73-380l3.2, Drer\zmp:0000000971, Drer\zgc:171470, Drer\robo4, Drer\ttnb, Drer\hmcn1, Drer\ttn.2" - "Cele\him-4, Cele\unc-89, Cele\ketn-1, Cele\ttn-1, Cele\unc-22" "Xtro\mylk, Xtro\MGC89178, Xtro\hmcn2, Xtro\egflam, Xtro\hmcn1, Xtro\obsl1" "Mmus\Speg, Mmus\Obsl1, Mmus\Myom3, Mmus\Ttn, Mmus\Mylk, Mmus\Obscn, Mmus\Hmcn2, Mmus\Vwa7, Mmus\Ptk7, Mmus\Egflam, Mmus\Hmcn1, Mmus\Mybpc3, Mmus\Igsf9" "Hsap\VWA7, Hsap\EGFLAM, Hsap\OBSL1, Hsap\HMCN1, Hsap\MYBPC3, Hsap\IGFN1, Hsap\IGSF9, Hsap\MYLK, Hsap\SPEG, Hsap\TTN, Hsap\IGSF22, Hsap\HMCN2, Hsap\PTK7, Hsap\OBSCN" " embryonic stage | stage 16 , embryonic stage | stage >=11 , embryonic stage | stage >=14 , embryonic stage | stage 11 , embryonic stage | stage >=13 , embryonic stage | late , larval stage | first instar " " muscle attachment site

, somatic mesoderm

, pharyngeal muscle

, mesoderm

, embryonic/larval somatic muscle

, visceral mesoderm

, embryonic/larval muscle system

, embryonic/larval visceral muscle

, embryonic/larval salivary gland

" " embryonic stage | stage >11 , embryonic stage , embryonic stage | stage >=13 , embryonic stage | stage > 11 , larval stage , embryonic stage | late , adult stage " " myotube

, muscle attachment site

, embryonic/larval visceral muscle

, embryonic/larval somatic muscle

, muscle founder cell

, muscle cell

, fusion competent cell

, pharyngeal muscle

" DRSC08540 K -0.422860456 -1.149455837 -0.083156843 -1.151268307 -0.019766246 2.37647943 FBgn0027086 IleRS Isoleucyl-tRNA synthetase http://flybase.org/reports/FBgn0027086 "FBgn0010728, FBgn0037159" protein_coding_gene "isoleucine-tRNA ligase activity ; GO:0004822 | inferred from electronic annotation with InterPro:IPR002301, InterPro:IPR023586 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002300, InterPro:IPR002301, InterPro:IPR009080 aminoacyl-tRNA editing activity ; GO:0002161 | inferred from electronic annotation with InterPro:IPR009008 tRNA binding ; GO:0000049 | inferred from electronic annotation with InterPro:IPR033709 isoleucine-tRNA ligase activity ; GO:0004822 | traceable author statement isoleucine-tRNA ligase activity ; GO:0004822 | inferred from sequence or structural similarity" isoleucyl-tRNA aminoacylation ; GO:0006428 | inferred from electronic annotation with InterPro:IPR002301 isoleucyl-tRNA aminoacylation ; GO:0006428 | traceable author statement cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002301 cytoplasm ; GO:0005737 | traceable author statement aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay "IleRS, IRS, l(3)00827, CG11471, Aats-ile" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002300:Aminoacyl-tRNA synthetase, class Ia, IPR002301:Isoleucine-tRNA ligase, IPR009008:Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR013155:Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR023586:Isoleucine-tRNA ligase, type 2, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR033709:Isoleucyl tRNA synthetase type 2, anticodon-binding domain" CG11471 11-Aug-17 DroID_v2017_08 "Drer\iars2, Drer\iars" "Scer\ISM1, Scer\ILS1" "Cele\iars-2, Cele\iars-1" Xtro\iars "Mmus\Iars2, Mmus\Iars" "Hsap\IARS, Hsap\IARS2" embryonic stage " embryonic/larval salivary gland

,

ubiquitous " "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0266137 Dop1R2 Dopamine 1-like receptor 2 http://flybase.org/reports/FBgn0266137 protein_coding_gene "dopamine neurotransmitter receptor activity ; GO:0004952 | inferred from sequence or structural similarity dopamine neurotransmitter receptor activity, coupled via Gs ; GO:0001588 | inferred from sequence or structural similarity with Dop1R1 inferred from sequence or structural similarity with HGNC:3020 inferred from direct assay adrenergic receptor activity ; GO:0004935 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 dopamine neurotransmitter receptor activity, coupled via Gs ; GO:0001588 | inferred from direct assay tyramine receptor activity ; GO:0008226 | inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity" "cell-cell signaling ; GO:0007267 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 response to odorant ; GO:1990834 | inferred from mutant phenotype regulation of presynaptic cytosolic calcium ion concentration ; GO:0099509 | inferred from mutant phenotype cellular response to dopamine ; GO:1903351 | inferred from mutant phenotype adenylate cyclase-activating adrenergic receptor signaling pathway ; GO:0071880 | inferred from biological aspect of ancestor with PANTHER:PTN001205212 G-protein coupled receptor signaling pathway ; GO:0007186 | traceable author statement age-dependent response to oxidative stress ; GO:0001306 | inferred from mutant phenotype dopamine receptor signaling pathway ; GO:0007212 | inferred from sequence or structural similarity adenylate cyclase-activating dopamine receptor signaling pathway ; GO:0007191 | inferred from direct assay negative regulation of circadian sleep/wake cycle, sleep ; GO:0042321 | inferred from mutant phenotype positive regulation of oxidative stress-induced neuron death ; GO:1903223 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 integral component of synaptic vesicle membrane ; GO:0030285 | inferred by curator from GO:0001588 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:280 inferred from sequence or structural similarity with HGNC:3023 "Damb, Dop1R2, damb, CG18741, DopR2, DAMB, DOPR99B, DopR99B, CG7569, Dar2, DopRII, DopD1, DOPR2, DDR2, K13sc, DR2, dopr2" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR002233:Adrenoceptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG18741 11-Aug-17 DroID_v2017_08 "Drer\htr7a, Drer\adrb1, Drer\adra1ba, Drer\adrb3b, Drer\adra1aa, Drer\adrb3a, Drer\gpr101, Drer\htr7b, Drer\adrb2a, Drer\adra1ab, Drer\adrb2b, Drer\LOC100536080, Drer\adra1d, Drer\adra1bb, Drer\htr7c" - "Cele\ser-5, Cele\dop-4" "Xtro\adra1d, Xtro\adra1b" "Mmus\Adra1a, Mmus\Adrb3, Mmus\Adrb2, Mmus\Adra1d, Mmus\Adra1b, Mmus\Htr7, Mmus\Adrb1, Mmus\Gpr101, Mmus\Hrh2" "Hsap\ADRB2, Hsap\ADRA1B, Hsap\ADRB3, Hsap\ADRA1A, Hsap\HRH2, Hsap\ADRB1, Hsap\HTR7, Hsap\GPR101, Hsap\ADRA1D" " adult stage , larval stage " mushroom body

" larval stage , adult stage " " lobe system of mushroom body

, mushroom body beta-lobe

, mushroom body gamma-lobe

, mushroom body alpha-lobe

, mushroom body

" FBgn0041186 Slbp Stem-loop binding protein http://flybase.org/reports/FBgn0041186 protein_coding_gene mRNA binding ; GO:0003729 | inferred from electronic annotation with InterPro:IPR026502 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSU4 RNA stem-loop binding ; GO:0035613 | inferred from direct assay mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from direct assay mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "dSLBP, SLBP, slbp, CG11886, dSLPB, Slbp" "IPR029344:Histone RNA hairpin-binding protein, RNA-binding domain, IPR026502:Histone RNA stem-loop-binding protein SLBP1/SLBP2" CG11886 11-Aug-17 DroID_v2017_08 "Drer\slbp2, Drer\slbp" - Cele\cdl-1 Xtro\slbp Mmus\Slbp Hsap\SLBP " embryonic stage | stage 5-12 , embryonic stage | pre-blastoderm , embryonic stage | stage >=11 , embryonic stage -- adult stage , embryonic stage | stage >=13 " " organism | ubiquitous

, organism

, embryonic peripheral nervous system

, embryonic midgut

, embryonic central nervous system

" "lethal,recessive,viable,partially lethal - majority die,female sterile,male fertile,lethal - all die before end of pupal stage,some die during pupal stage,maternal effect,partially lethal - majority live,wild-type" "nuclear chromosome,mitotic cell cycle" FBgn0023179 amon amontillado http://flybase.org/reports/FBgn0023179 FBgn0004877 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR000209, InterPro:IPR002884 peptidase activity ; GO:0008233 | inferred from direct assay" proteolysis ; GO:0006508 | inferred from direct assay larval wandering behavior ; GO:0035180 | inferred from mutant phenotype carbohydrate homeostasis ; GO:0033500 | inferred from mutant phenotype instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype hatching behavior ; GO:0035187 | inferred from mutant phenotype peptide hormone processing ; GO:0016486 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay "dPC2, PC2, PPP, DMH#5, Ppp, CG6438, amon, Amon" "IPR000209:Peptidase S8/S53 domain, IPR002884:Proprotein convertase, P, IPR008979:Galactose-binding domain-like, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR032815:Peptidase S8, pro-domain, IPR015500:Peptidase S8, subtilisin-related, IPR023827:Peptidase S8, subtilisin, Asp-active site, IPR023828:Peptidase S8, subtilisin, Ser-active site, IPR034182:Kexin/furin catalytic domain, IPR022398:Peptidase S8, subtilisin, His-active site" CG6438 11-Aug-17 DroID_v2017_08 "Drer\pcsk5a, Drer\pcsk1, Drer\LOC100330575, Drer\furinb, Drer\furina, Drer\pcsk2, Drer\pcsk7, Drer\pcsk5b, Drer\fras1, Drer\rspo3" Scer\KEX2 "Cele\aex-5, Cele\kpc-1, Cele\egl-3" "Xtro\pcsk4, Xtro\pcsk2, Xtro\pcsk5, Xtro\furin, Xtro\pcsk7, Xtro\fras1, Xtro\rspo3, Xtro\pcsk6, Xtro\pcsk1" "Mmus\Pcsk6, Mmus\Pcsk2, Mmus\Pcsk1, Mmus\Furin, Mmus\Pcsk5, Mmus\Rspo3, Mmus\Pcsk7, Mmus\Rspo4, Mmus\Pcsk4, Mmus\Fras1, Mmus\Rspo1" "Hsap\PCSK7, Hsap\PCSK1, Hsap\PCSK2, Hsap\RSPO4, Hsap\PCSK5, Hsap\FRAS1, Hsap\RSPO3, Hsap\PCSK6, Hsap\PCSK4, Hsap\FURIN, Hsap\RSPO1" " embryonic stage | stage 17 , larval stage | first instar , larval stage | second instar , embryonic stage | stage >=15 , larval stage--adult stage , embryonic stage | stage >=16 " " larval labral segment sense organ

, larval brain | restricted

, ventral nerve cord | restricted

, embryonic frontal ganglion

, embryonic peripheral nervous system | restricted

, larval protocerebrum | restricted

, antenno-maxillary complex

, embryonic digestive system | restricted

, organism

, ring gland

, ventral nerve cord

segmentally repeated , embryonic brain

, embryonic/larval endocrine system | restricted

" "lethal,recessive,heat sensitive,small body,hypoactive,behavior defective,locomotor behavior defective" "larval head,leg,wing,wing disc,mesothoracic leg disc,metathoracic leg disc,prothoracic leg disc,ventral thoracic disc" FBgn0003886 alphaTub85E alpha-Tubulin at 85E http://flybase.org/reports/FBgn0003886 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002452, InterPro:IPR008280, InterPro:IPR017975 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002452 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity" mitotic spindle assembly checkpoint ; GO:0007094 | inferred from direct assay centrosome duplication ; GO:0051298 | inferred from mutant phenotype "microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002452, InterPro:IPR017975 microtubule ; GO:0005874 | inferred from sequence or structural similarity" "Tub, alpha85E-tub, alpha-tubulin, alpha-Tub, alpha85E, CG9476, ALPHA 85E, alpha2, aTub85E, alphaTub84E, alphaTub2, a2t, T, 2t, DTA3, alpha2t, alpha-Tub85E, alphaTub85E, alphaTub, alpha-tub, Tub1D, alphatub85E" "IPR000217:Tubulin, IPR002452:Alpha tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain" CG9476 11-Aug-17 DroID_v2017_08 "Drer\tuba8l4, Drer\tuba4l, Drer\tuba8l, Drer\tuba1c, Drer\si:ch211-114n24.6, Drer\si:ch73-199e17.1, Drer\tuba1b, Drer\tuba2, Drer\tuba1a, Drer\tuba7l, Drer\tuba8l3, Drer\tuba8l2" "Scer\TUB3, Scer\TUB1" "Cele\tba-5, Cele\tba-2, Cele\tba-7, Cele\tba-4, Cele\tba-6, Cele\tba-8, Cele\tba-9, Cele\mec-12, Cele\tba-1" "Xtro\tuba3e, Xtro\tuba1a, Xtro\tuba3c, Xtro\tuba4, Xtro\tuba1c, Xtro\tubal3, Xtro\tuba4a, Xtro\tuba4b, Xtro\tuba8" "Mmus\Tubal3, Mmus\Tuba1c, Mmus\Tuba4a, Mmus\Tuba3a, Mmus\Tuba1b, Mmus\Tuba8, Mmus\Tuba1a, Mmus\Tuba3b" "Hsap\TUBA1B, Hsap\TUBA3E, Hsap\TUBA1A, Hsap\TUBAL3, Hsap\TUBA8, Hsap\TUBA1C, Hsap\TUBA4A, Hsap\TUBA3D, Hsap\TUBA3C" " larval stage | third instar , embryonic stage | >=8-12 hr , pupal stage , larval stage | second instar , larval stage--pupal stage , embryonic stage | 0-6 hr , larval stage | first instar , adult stage | male , larval stage , embryonic stage | 6-12 hr , prepupal stage , spermatogenesis && adult stage , embryonic stage | 2-21 hr " testis

" larval stage , embryonic stage | 16-20 hr , larval stage | third instar , spermatogenesis && adult stage " " imaginal disc

, dorsal mesothoracic disc

, testis

" "visible,male fertile" "wing,spermatid" DRSC16899 IE 2.743602807 -2.834850659 1.878470708 -2.002112452 -0.210120662 0.140310026 FBgn0262562 CG43102 - http://flybase.org/reports/FBgn0262562 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with RhoGEF4 positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with RhoGEF4 cellular_component ; GO:0005575 | no biological data available "CG43102, CG7397, FBgn0038543, CG14318" "IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR017986:WD40-repeat-containing domain, IPR000219:Dbl homology (DH) domain, IPR011993:PH domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG43102 11-Aug-17 DroID_v2017_08 "Drer\arhgef10la, Drer\arhgef10, Drer\si:ch211-248g20.5" - Cele\osg-1 - "Mmus\Arhgef10, Mmus\Arhgef10l, Mmus\Arhgef17" "Hsap\ARHGEF10L, Hsap\ARHGEF10, Hsap\ARHGEF17" DRSC14797 K 0.634611321 -0.603085 0.187190951 -0.64125462 -1.854268152 -0.275655533 FBgn0261394 Prosalpha3 Proteasome alpha3 subunit http://flybase.org/reports/FBgn0261394 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR000426 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426 microtubule associated complex ; GO:0005875 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay" "Prosalpha3, CG9327, Pros20S-alpha3, pros29, alpha3_dm, PROS-29, PSB3_DROME, Alpha-3, Pros29, alpha3, alpha-3" "IPR023332:Proteasome alpha-type subunit, IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR029055:Nucleophile aminohydrolases, N-terminal, IPR034647:Proteasome subunit alpha4" CG9327 11-Aug-17 DroID_v2017_08 "Drer\p4hb, Drer\psmb3, Drer\psma4" "Scer\PRE9, Scer\PUP3" "Cele\pas-3, Cele\pbs-3" "Xtro\psmb3, Xtro\psma4" "Mmus\Psmb3, Mmus\Psma4" "Hsap\PSMB3, Hsap\PSMA4" DRSC04644 IE -1.444658099 -1.746599131 -3.564983288 -1.562301672 0.832298596 1.224119008 FBgn0036820 Grx1 Glutaredoxin 1 http://flybase.org/reports/FBgn0036820 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR002109 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR002109 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR002109, InterPro:IPR011899 copper ion homeostasis ; GO:0055070 | inferred from genetic interaction with ATP7 inferred from genetic interaction with Ctr1B inferred from genetic interaction with Ctr1A response to copper ion ; GO:0046688 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "BcDNA:GH24739, CG6852, Grx1" "IPR002109:Glutaredoxin, IPR011899:Glutaredoxin, eukaryotic/virial, IPR012336:Thioredoxin-like fold, IPR014025:Glutaredoxin subgroup" CG6852 11-Aug-17 DroID_v2017_08 "Drer\glrx2, Drer\txnrd1, Drer\glrx" "Scer\GRX2, Scer\GRX8, Scer\GRX1, Scer\GRX7, Scer\PRM4, Scer\GRX6" "Cele\ZC334.7, Cele\glrx-22, Cele\glrx-21, Cele\glrx-10, Cele\F10D7.3" "Xtro\txnrd1, Xtro\glrx, Xtro\txnrd3, Xtro\glrx2" "Mmus\Txnrd3, Mmus\Glrx, Mmus\Glrx2" "Hsap\TXNRD3, Hsap\GLRX, Hsap\GLRX2, Hsap\TXNRD1" "viable,fertile,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC10727 E -0.97519337 -0.180433884 1.623643401 -0.15989378 -0.469953825 -0.398453885 FBgn0267336 Glut4EF Glucose transporter 4 enhancer factor http://flybase.org/reports/FBgn0267336 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "CG34360, Glut4EF, D-Glut4EF, stretch, BcDNA:GH25505, CG33975, CG11676, BcDNA:GM06804, CG32469, BcDNA:RH63124, CG12804, CG12805, CG12802, BcDNA:RE66512, CG43757" "IPR013087:Zinc finger C2H2-type, IPR031940:Domain of unknown function DUF4772" CG34360 11-Aug-17 DroID_v2017_08 "Drer\znf395b, Drer\znf395a, Drer\si:rp71-79p20.2, Drer\znf704" - - Xtro\znf395 "Mmus\Zfp395, Mmus\Zfp704" "Hsap\SLC2A4RG, Hsap\ZNF704, Hsap\ZNF395" DRSC14541 I 0.055133671 1.579810479 0.206630611 0.329188832 -0.575176756 -0.077960702 FBgn0002593 RpLP1 Ribosomal protein LP1 http://flybase.org/reports/FBgn0002593 - protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement protein kinase activator activity ; GO:0030295 | inferred from biological aspect of ancestor with PANTHER:PTN000474938 structural constituent of ribosome ; GO:0003735 | inferred from direct assay translational elongation ; GO:0006414 | inferred from electronic annotation with InterPro:IPR027534 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement positive regulation of protein kinase activity ; GO:0045860 | inferred from biological aspect of ancestor with PANTHER:PTN000474938 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay "CG4087, RpP2, rpP2, M(2)21C, rp21C, M(2)21C1-2, rpa2, rpA2, RpA2, RpLP1, LP1, RLA1_DROME, Rplp1, chr2L:420593..420726" IPR027534:Ribosomal protein L12 family CG4087 11-Aug-17 DroID_v2017_08 Drer\rplp1 "Scer\RPP1A, Scer\RPP1B, Scer\CCT2" "Cele\rla-1, Cele\mrt-2" Xtro\rplp1 "Mmus\Cct2, Mmus\Rplp1" Hsap\RPLP1 "lethal,recessive,Minute,dominant,developmental rate defective,size defective" "chaeta,macrochaeta,adult heart" DRSC00783 IEK -3.291973223 -3.324180458 -1.588514139 -5.176080751 -0.417148183 1.831510531 FBgn0003141 pr purple http://flybase.org/reports/FBgn0003141 FBgn0020600 protein_coding_gene "6-pyruvoyltetrahydropterin synthase activity ; GO:0003874 | inferred from electronic annotation with InterPro:IPR022469, InterPro:IPR022470" "tetrahydrobiopterin biosynthetic process ; GO:0006729 | inferred from electronic annotation with InterPro:IPR022469, InterPro:IPR022470 pteridine biosynthetic process ; GO:0006728 | inferred from direct assay" - "38B.9, anon-38Bb, CG16784, pr" "IPR007115:6-pyruvoyl tetrahydropterin synthase/QueD family protein, IPR022469:6-pyruvoyl tetrahydropterin synthase, histidine active site, IPR022470:6-pyruvoyl tetrahydropterin synthase, cysteine active site" CG16784 11-Aug-17 DroID_v2017_08 Drer\pts - Cele\ptps-1 Xtro\pts Mmus\Pts Hsap\PTS embryonic stage -- adult stage "lethal,recessive,eye color defective,visible" pigment cell DRSC03596 IE 1.67503972 1.071070612 2.735635247 -1.293602158 0.021888337 -0.692367585 FBgn0050373 CG30373 - http://flybase.org/reports/FBgn0050373 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RH67738, CG30373" IPR029160:CCSMST1 family CG30373 11-Aug-17 DroID_v2017_08 - - - - Mmus\BC003965 Hsap\C16orf91 "viable,visible" trichogen cell DRSC29668 K -0.589698746 0.387429435 0.965165564 0.584324136 0.165157606 1.587392624 FBgn0259146 fid fire dancer http://flybase.org/reports/FBgn0259146 protein_coding_gene "tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 tRNA (uracil) methyltransferase activity ; GO:0016300 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors ; GO:0016706 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 ferrous iron binding ; GO:0008198 | inferred from biological aspect of ancestor with PANTHER:PTN001405577" detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype tRNA wobble uridine modification ; GO:0002098 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000317053 "CG14541, CG8968, fid, CG42261" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR032873:Probable tRNA methyltransferase 9-like protein, IPR013216:Methyltransferase type 11" CG42261 11-Aug-17 DroID_v2017_08 "Drer\alkbh8, Drer\zgc:73340" Scer\TRM9 "Cele\alkb-8, Cele\C35D10.12" "Xtro\kiaa1456, Xtro\alkbh8" "Mmus\Alkbh8, Mmus\6430573F11Rik" "Hsap\KIAA1456, Hsap\ALKBH8" DRSC16464 IE 0.571896469 -1.855635129 1.531879575 -1.728271517 0.512328221 0.4268913 FBgn0000182 BicC Bicaudal C http://flybase.org/reports/FBgn0000182 - protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA binding ; GO:0003729 | traceable author statement mRNA binding ; GO:0003729 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with orb oogenesis ; GO:0048477 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype negative regulation of oskar mRNA translation ; GO:0007319 | traceable author statement ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype - "Bic-C, BG:DS00913.2, br34, l(2)br34, CG4824, BicC, BICC, Dromel_CG4824_FBtr0080804_bicc_mORF" "IPR001660:Sterile alpha motif domain, IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR013761:Sterile alpha motif/pointed domain" CG4824 11-Aug-17 DroID_v2017_08 "Drer\hdlbpa, Drer\bicc2, Drer\bicc1a, Drer\hdlbpb, Drer\bicc1b" "Scer\YLL032C, Scer\SCP160" "Cele\bcc-1, Cele\gld-3" "Xtro\bicc1, Xtro\hdlbp, Xtro\anks6" "Mmus\Hdlbp, Mmus\Gm382, Mmus\Bicc1, Mmus\Anks6" "Hsap\ANKS6, Hsap\HDLBP, Hsap\BICC1" " adult stage | female , adult stage && oogenesis stage | stage S8-9 , adult stage && oogenesis stage | stage >=S10 , embryonic stage | 0-4 hr , adult stage | male , adult stage && oogenesis stage | stage S1-7 , adult stage && oogenesis stage " " oocyte | anterior

, nurse cell

, oocyte

, germarium region 2a && germarium region 2b && germarium region 3

, germarium region 2a && germarium region 2b && germarium region 3

" " adult stage && oogenesis stage | stage >=S10 , adult stage && oogenesis stage | stage S3-10 " " nurse cell

, oocyte

" "lethal,maternal effect,female sterile,dominant,lethal - all die before end of embryonic stage,partially,some die during embryonic stage,recessive,viable" "dorsal appendage,follicle cell,microtubule & oocyte,nurse cell,maternal effect,pole cell,embryonic head,oocyte,egg,embryo" FBgn0004839 otk off-track http://flybase.org/reports/FBgn0004839 FBgn0082205 protein_coding_gene "protein tyrosine kinase activity ; GO:0004713 | inferred from electronic annotation with InterPro:IPR020635 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway ; GO:1904929 | inferred from electronic annotation with InterPro:IPR033592 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 receptor activity ; GO:0004872 | inferred from sequence or structural similarity with UniProtKB:Q6AWJ9 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O96681 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with UniProtKB:Q6AWJ9 receptor activity ; GO:0004872 | inferred from sequence or structural similarity inferred from direct assay cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity inferred from direct assay cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity with UniProtKB:Q6AWJ9 Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt2 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein homodimerization activity ; GO:0042803 | inferred from physical interaction with otk semaphorin receptor binding ; GO:0030215 | traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from sequence or structural similarity Wnt-protein binding ; GO:0017147 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with otk2" "convergent extension ; GO:0060026 | inferred from electronic annotation with InterPro:IPR033592 establishment of planar polarity ; GO:0001736 | inferred from electronic annotation with InterPro:IPR033592 protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR020635 cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with UniProtKB:Q6AWJ9 axon guidance ; GO:0007411 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from sequence or structural similarity inferred from direct assay retinal ganglion cell axon guidance ; GO:0031290 | inferred from sequence or structural similarity with UniProtKB:Q6AWJ9 axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with Sema1a inferred from genetic interaction with PlexA imaginal disc-derived female genitalia morphogenesis ; GO:0048804 | inferred from genetic interaction with otk2 retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from mutant phenotype imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from genetic interaction with otk2 protein phosphorylation ; GO:0006468 | non-traceable author statement internal genitalia morphogenesis ; GO:0035260 | inferred from genetic interaction with otk2" integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR033592 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q6AWJ9 "OTK, Otk, Dtrk, dTrk, CT25769, OFT/TRK, CG8967, DTrk, Trk48D, Tk48D, IGGtyk, Dtkr, anon-WO2004063362.81, otk" "IPR000719:Protein kinase domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013783:Immunoglobulin-like fold, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR033592:Inactive tyrosine-protein kinase 7, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR013098:Immunoglobulin I-set" CG8967 11-Aug-17 DroID_v2017_08 "Drer\LOC100148735, Drer\ror2, Drer\spegb, Drer\si:dkey-14o18.6, Drer\ptk7b, Drer\zmp:0000000971, Drer\ntrk2a, Drer\zmp:0000001289, Drer\il1rapl1b, Drer\vwa7, Drer\si:ch211-171h4.5, Drer\si:ch73-380l3.2, Drer\ptk7a, Drer\zgc:172106, Drer\hmcn2, Drer\LOC101885775, Drer\si:ch211-1f22.3, Drer\LOC100006752, Drer\LOC100535144, Drer\ntrk1, Drer\il1rapl2, Drer\si:ch211-286b5.9, Drer\LOC101884775, Drer\ntrk3b, Drer\vwa11, Drer\ttnb, Drer\ntrk2b, Drer\LOC100333105, Drer\il1rapl1a, Drer\ntrk3a, Drer\vwa10.2, Drer\sc:d0284, Drer\vwa10.1, Drer\ror1, Drer\LOC100333244, Drer\scospondin, Drer\zgc:171470, Drer\cd22, Drer\LOC799279" "Scer\SCH9, Scer\BCK1, Scer\SKM1" - "Xtro\ntrk1, Xtro\hmcn2, Xtro\ptk7, Xtro\MGC89178, Xtro\musk" "Mmus\Obscn, Mmus\Il18rap, Mmus\Il1rapl1, Mmus\Il1rap, Mmus\Il18r1, Mmus\Vwa7, Mmus\Hmcn2, Mmus\Ntrk3, Mmus\Ntrk1, Mmus\Ror1, Mmus\Hmcn1, Mmus\Il1rl2, Mmus\Il1r1, Mmus\Il1rl1, Mmus\Ptk7, Mmus\Ntrk2, Mmus\Il1rapl2" "Hsap\NTRK2, Hsap\IL18RAP, Hsap\NTRK3, Hsap\IL1RAPL1, Hsap\HMCN1, Hsap\VWA7, Hsap\IL1RL2, Hsap\ROR2, Hsap\IL1RAPL2, Hsap\IL1R1, Hsap\OBSCN, Hsap\IL1RAP, Hsap\IL1RL1, Hsap\IL18R1, Hsap\PTK7" embryonic stage&&pupal stage " embryonic stage | stage 13 , embryonic stage | stage 11 , embryonic stage | late , embryonic stage | stage 12 , embryonic stage | stage 7 , embryonic stage | stage 7-11 , embryonic stage | stage 12-17 " " embryonic/larval hindgut

, posterior midgut proper primordium

, embryonic/larval midgut

, epidermis | restricted

, posterior commissure

, visceral mesoderm

, maxillary segment

, peripheral nervous system | restricted

, ventral nerve cord

, epidermis | segmentally repeated

, neuron

, proctodeum | primordium

, cell body

, cephalic furrow

, anterior midgut proper primordium

, neuroblast

, neuron

, procephalic segment

, anterior commissure

" "viable,female sterile,partially lethal - majority die,wild-type,visible,planar polarity defective" "oviduct,photoreceptor cell R2 & axon & larva[-],photoreceptor cell R3 & axon & larva[-],photoreceptor cell R4 & axon & larva[-],photoreceptor cell R5 & axon & larva[-],photoreceptor cell R6 & axon & larva[-],axonelav.PLu,intersegmental nerve,abdominal segmental nerve,axon,eye photoreceptor cell & axon & larva | somatic clone,photoreceptor cell R1 & axon & larva | somatic clone,photoreceptor cell R2 & axon & larva | somatic clone,photoreceptor cell R3 & axon & larva | somatic clone,photoreceptor cell R4 & axon & larva | somatic clone,photoreceptor cell R5 & axon & larva | somatic clone,photoreceptor cell R6 & axon & larva | somatic clone,lamina & glial cell & larva | somatic clone,photoreceptor cell R1 & axon | somatic clone,photoreceptor cell R2 & axon | somatic clone,photoreceptor cell R3 & axon | somatic clone,photoreceptor cell R4 & axon | somatic clone,photoreceptor cell R5 & axon | somatic clone,photoreceptor cell R6 & axon | somatic clone,medulla,somatic clone,denticle belt,ectopic,embryonic/first instar larval cuticle,wing margin,wing hair" FBgn0015583 Acp29AB Accessory gland protein 29AB http://flybase.org/reports/FBgn0015583 - protein_coding_gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 sperm competition ; GO:0046692 | traceable author statement multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sperm storage ; GO:0046693 | inferred from mutant phenotype sperm competition ; GO:0046692 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "CG17797, Acp29AB-II, AC004423b, AC 004423B, Acp29B, Acp29AB, Acp29" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG17797 11-Aug-17 DroID_v2017_08 "Drer\hbl2, Drer\hbl1, Drer\colec11, Drer\clec11a, Drer\hbl4, Drer\hbl3" - Cele\clec-149 - "Mmus\Klri1, Mmus\Mbl1, Mmus\Colec10, Mmus\Colec11, Mmus\Klri2, Mmus\Cd209g, Mmus\Sftpd" "Hsap\COLEC10, Hsap\CLEC3B, Hsap\CLEC3A, Hsap\CLEC4A, Hsap\COLEC11, Hsap\CD209, Hsap\SFTPD" adult stage | male " male accessory gland main cell

, male accessory gland

" "viable,visible,partially lethal - majority die,some die during pupal stage,fertile" trichogen cell FBgn0011584 Trp1 Translocation protein 1 http://flybase.org/reports/FBgn0011584 FBgn0011838 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with SGD:S000006015 "posttranslational protein targeting to membrane, translocation ; GO:0031204 | inferred from sequence or structural similarity with SGD:S000006015" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004728 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000006015 endomembrane system ; GO:0012505 | inferred from direct assay "sec62, Dtrp1, Tp1, CG4758, Trp1" "IPR004728:Translocation protein Sec62, IPR011991:Winged helix-turn-helix DNA-binding domain" CG4758 11-Aug-17 DroID_v2017_08 Drer\sec62 Scer\SEC62 Cele\C18E9.2 Xtro\sec62 Mmus\Sec62 Hsap\SEC62 " spermatogenesis && adult stage , adult stage | female , oogenesis stage && adult stage | female , embryonic stage -- adult stage , adult stage | male " " testis

, ovary

, ejaculatory duct

, male accessory gland

" "visible,uncoordinated,viable,body color defective" "wing,embryonic/larval hemocyte | third instar larval stage,trichogen cell,mesothoracic tergum" FBgn0003248 Rh2 Rhodopsin 2 http://flybase.org/reports/FBgn0003248 - protein_coding_gene G-protein coupled photoreceptor activity ; GO:0008020 | inferred from direct assay G-protein coupled photoreceptor activity ; GO:0008020 | non-traceable author statement G-protein coupled photoreceptor activity ; GO:0008020 | traceable author statement G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with ninaE "visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR001760 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR001735, InterPro:IPR001760 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity phototransduction ; GO:0007602 | non-traceable author statement phototransduction ; GO:0007602 | inferred from genetic interaction with ninaE" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR001735, InterPro:IPR001760, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "Rh2, Rh, DMELRH2, Dm Rh2, RH2, CG16740, rh2" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001735:Opsin RH1/RH2, IPR001760:Opsin, IPR017452:GPCR, rhodopsin-like, 7TM, IPR027430:Visual pigments (opsins) retinal binding site" CG16740 11-Aug-17 DroID_v2017_08 "Drer\parietopsin, Drer\opn9, Drer\tmtopsb, Drer\opn7d, Drer\opn1sw1, Drer\opn4.1, Drer\rho, Drer\rhol, Drer\opn1mw3, Drer\parapinopsinb, Drer\opn1mw1, Drer\opn5, Drer\opn4b, Drer\opn4xa, Drer\opn7c, Drer\opn6a, Drer\valopa, Drer\tmtops2b, Drer\opn1lw1, Drer\opn1lw2, Drer\tmtops3a, Drer\exorh, Drer\opn6b, Drer\opn4a, Drer\opn8c, Drer\opn1mw4, Drer\opn3, Drer\opn1sw2, Drer\rrh, Drer\opn7b, Drer\opn4xb, Drer\opn8b, Drer\opn7a, Drer\valopb, Drer\tmtops3b, Drer\tmtops2a" - "Cele\ZK418.6, Cele\gnrr-5, Cele\ZK418.7, Cele\npr-1" "Xtro\opn1lw, Xtro\rrh, Xtro\LOC100485989, Xtro\opn5, Xtro\opn1sw, Xtro\rho, Xtro\LOC100124934, Xtro\tmtops.2, Xtro\LOC100485437, Xtro\tmtops, Xtro\opn4" "Mmus\Rho, Mmus\Opn1mw, Mmus\Opn1sw, Mmus\Opn5, Mmus\Opn3, Mmus\Opn4, Mmus\Rrh" "Hsap\OPN1MW, Hsap\RRH, Hsap\OPN1MW3, Hsap\OPN5, Hsap\OPN1LW, Hsap\OPN4, Hsap\OPN1SW, Hsap\OPN3, Hsap\RHO, Hsap\OPN1MW2" " adult stage , spermatogenesis && adult stage " " ocellus

, adult head

, photoreceptor cell R8

, testis

" adult stage " photoreceptor cell R1--6

, photoreceptor cell R1..6

{ $ ninaA* } " "viable,visible" "chaeta,supernumerary" FBgn0034534 maf-S maf-S http://flybase.org/reports/FBgn0034534 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR004827 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with cnc transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from direct assay" head development ; GO:0060322 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR004826, InterPro:IPR024874" "CG9954, maf2, anon-EST:Posey173, maf-S, Maf-S, MafS, Maf, DM31, DM19, MAF-S" "IPR004826:Basic leucine zipper domain, Maf-type, IPR004827:Basic-leucine zipper domain, IPR008917:Transcription factor, Skn-1-like, DNA-binding domain, IPR024874:Transcription factor Maf family" CG9954 11-Aug-17 DroID_v2017_08 "Drer\mafbb, Drer\mafgb, Drer\mafb, Drer\mafk, Drer\maff, Drer\mafga, Drer\mafa, Drer\mafaa, Drer\nrl, Drer\mafba" - Cele\maf-1 "Xtro\nrl, Xtro\maff, Xtro\mafk, Xtro\maf, Xtro\mafb, Xtro\mafg" "Mmus\Mafk, Mmus\Mafb, Mmus\Maf, Mmus\Mafa, Mmus\Nrl, Mmus\Maff, Mmus\Mafg" "Hsap\MAFG, Hsap\MAFB, Hsap\NRL, Hsap\MAFA, Hsap\MAFF, Hsap\MAF, Hsap\MAFK" "oxidative stress response defective,viable,chemical sensitive" "mouth hooks,supernumerary,lateral process,median tooth,embryonic/larval pharynx,ventral" DRSC07348 K 0.629538968 -1.224037685 0.312948847 0.277857815 1.146588183 1.744531212 FBgn0087035 AGO2 Argonaute 2 http://flybase.org/reports/FBgn0087035 protein_coding_gene siRNA binding ; GO:0035197 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with AGO1 protein binding ; GO:0005515 | inferred from physical interaction with Fmr1 protein binding ; GO:0005515 | inferred from physical interaction with Dcr-1 endoribonuclease activity ; GO:0004521 | inferred from direct assay "cellularization ; GO:0007349 | inferred from mutant phenotype negative regulation of viral genome replication ; GO:0045071 | inferred from mutant phenotype targeting of mRNA for destruction involved in RNA interference ; GO:0030423 | traceable author statement heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern RNA interference ; GO:0016246 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from direct assay defense response to virus ; GO:0051607 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from genetic interaction with AGO1 dosage compensation by hyperactivation of X chromosome ; GO:0009047 | inferred from genetic interaction with roX2, roX1 siRNA loading onto RISC involved in RNA interference ; GO:0035087 | inferred from mutant phenotype negative regulation of transposition, RNA-mediated ; GO:0010526 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | NOT inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from direct assay RNA interference ; GO:0016246 | traceable author statement gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype syncytial nuclear migration ; GO:0035190 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern cellular response to virus ; GO:0098586 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from mutant phenotype siRNA loading onto RISC involved in RNA interference ; GO:0035087 | inferred from direct assay" RISC complex ; GO:0016442 | traceable author statement RISC complex ; GO:0016442 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay RISC-loading complex ; GO:0070578 | inferred from direct assay "ago, Ago2, AGO2, ago2, Ago-2, eIF2C2, ago-2, AG02, dAgo2, AGO 2, CG7439, Dm Ago2, dAGO2, CG13452, DmAgo2, argonaute2, Ago2a" "IPR003100:PAZ domain, IPR003165:Piwi domain, IPR012337:Ribonuclease H-like domain, IPR014811:Argonaute, linker 1 domain, IPR032473:Protein argonaute, Mid domain, IPR032474:Protein argonaute, N-terminal, IPR032472:Argonaute linker 2 domain" CG7439 11-Aug-17 DroID_v2017_08 "Drer\ago1, Drer\ago2, Drer\ago3b, Drer\LOC567622, Drer\piwil2, Drer\piwil1, Drer\ago4" - "Cele\sago-2, Cele\nrde-3, Cele\C03D6.1, Cele\wago-4, Cele\ppw-1, Cele\hpo-24, Cele\sago-1, Cele\wago-5, Cele\rde-1, Cele\prg-2, Cele\ZK218.8, Cele\C04F12.1, Cele\csr-1, Cele\wago-10, Cele\wago-1, Cele\alg-3, Cele\alg-1, Cele\hrde-1, Cele\alg-2, Cele\prg-1, Cele\wago-11, Cele\alg-4, Cele\ppw-2, Cele\ergo-1" "Xtro\ago4, Xtro\ago2, Xtro\piwil2, Xtro\piwil4, Xtro\ago3, Xtro\piwil3" "Mmus\Ago3, Mmus\Piwil4, Mmus\Ago1, Mmus\Ago2, Mmus\Piwil2, Mmus\Piwil1, Mmus\Ago4" "Hsap\PIWIL4, Hsap\AGO4, Hsap\PIWIL2, Hsap\AGO3, Hsap\AGO1, Hsap\PIWIL1, Hsap\AGO2" DRSC10847 IE -2.847199926 -4.680947 -4.670712475 -3.774338879 0.177515034 0.750577986 FBgn0005670 Cyp4d1 Cytochrome P450-4d1 http://flybase.org/reports/FBgn0005670 FBgn0010221 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" lipid particle ; GO:0005811 | inferred from direct assay "CG3656, 4d1, EG:87B1.1, CYP4D1, P450, P-450, Cyt-P450-4D1, Cyp4D1, Cyp4d1, cyp4d1, CYP6D1" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG3656 11-Aug-17 DroID_v2017_08 "Drer\cyp4v8, Drer\cyp4v7, Drer\cyp3c2, Drer\cyp3c4, Drer\cyp19a1b, Drer\cyp46a1.4, Drer\cyp4t8, Drer\cyp3c1, Drer\cyp26a1, Drer\cyp3a65, Drer\cyp20a1, Drer\cyp46a1.2, Drer\cyp26b1, Drer\cyp46a1.3, Drer\cyp26c1, Drer\cyp4f3, Drer\cyp19a1a, Drer\LOC100329425, Drer\cyp46a1.1, Drer\cyp3c3" "Scer\ERG5, Scer\DIT2" "Cele\cyp-13A1, Cele\cyp-13A10, Cele\cyp-13A12, Cele\cyp-13A8, Cele\cyp-31A5, Cele\cyp-32B1, Cele\cyp-42A1, Cele\cyp-25A2, Cele\cyp-13A11, Cele\cyp-31A2, Cele\cyp-13A7, Cele\cyp-37B1, Cele\cyp-31A3, Cele\cyp-13A4, Cele\cyp-25A4, Cele\cyp-13A5, Cele\cyp-25A1, Cele\cyp-37A1, Cele\cyp-29A3, Cele\cyp-25A3, Cele\cyp-13A3, Cele\cyp-32A1, Cele\cyp-29A4, Cele\cyp-29A2" "Xtro\cyp26c1, Xtro\cyp26b1, Xtro\mgc108213, Xtro\cyp26a1, Xtro\cyp4f2, Xtro\cyp4f22, Xtro\cyp4v2, Xtro\cyp4b1.2, Xtro\LOC100487918, Xtro\cyp19a1, Xtro\LOC100488227, Xtro\cyp4b1, Xtro\cyp20a1" "Mmus\Cyp4a32, Mmus\Cyp4f18, Mmus\Cyp4f17, Mmus\Cyp3a41b, Mmus\Cyp4a29, Mmus\Cyp4f37, Mmus\Cyp4a30b, Mmus\Cyp3a57, Mmus\Cyp4x1, Mmus\Cyp4f15, Mmus\Cyp4f39, Mmus\Cyp26a1, Mmus\Cyp26c1, Mmus\Cyp4a12b, Mmus\Cyp3a41a, Mmus\Cyp20a1, Mmus\Cyp3a11, Mmus\Cyp4a31, Mmus\Cyp26b1, Mmus\Cyp3a25, Mmus\Cyp4a10, Mmus\Cyp46a1, Mmus\Cyp4b1, Mmus\Cyp3a59, Mmus\Cyp4f40, Mmus\Cyp3a16, Mmus\Cyp4a14, Mmus\Cyp4v3, Mmus\Cyp3a13, Mmus\Cyp4f16, Mmus\Cyp4f14, Mmus\Cyp4f13, Mmus\Cyp19a1, Mmus\Cyp4a12a, Mmus\Cyp3a44" "Hsap\CYP4A22, Hsap\CYP4F2, Hsap\CYP4B1, Hsap\CYP4F11, Hsap\CYP4X1, Hsap\CYP4F8, Hsap\CYP46A1, Hsap\CYP26C1, Hsap\CYP4A11, Hsap\CYP4F22, Hsap\CYP3A5, Hsap\CYP3A4, Hsap\CYP4F3, Hsap\CYP4F12, Hsap\CYP26A1, Hsap\CYP4V2, Hsap\CYP4Z1, Hsap\CYP3A7, Hsap\CYP3A43, Hsap\CYP19A1, Hsap\CYP20A1, Hsap\CYP26B1" " embryonic stage -- adult stage , larval stage | third instar " viable DRSC17694 K -1.311069076 -0.031261123 0.202148543 0.085377742 1.529260967 -0.04008493 FBgn0033260 Cul4 Cullin 4 http://flybase.org/reports/FBgn0033260 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000231993 ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Roc1a "protein ubiquitination ; GO:0016567 | inferred by curator from GO:0031625,GO:0080008 eggshell chorion gene amplification ; GO:0007307 | inferred from direct assay positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with UniProtKB:Q13618 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000231993" Cul4-RING E3 ubiquitin ligase complex ; GO:0080008 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Cul-4, CUL4, Cul4, CG8711, DMcul-4, dCul4, cul-4, Cullin4, Cullin 4, cul4" "IPR001373:Cullin, N-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016157:Cullin, conserved site, IPR016158:Cullin homology, IPR016159:Cullin repeat-like-containing domain, IPR019559:Cullin protein, neddylation domain" CG8711 11-Aug-17 DroID_v2017_08 "Drer\cul3a, Drer\cul4a, Drer\cul4b, Drer\cul3b" "Scer\RTT101, Scer\CDC53, Scer\CUL3" Cele\cul-4 "Xtro\cul3, Xtro\cul4b, Xtro\cul4a" "Mmus\Cul4b, Mmus\Cul4a, Mmus\Cul3" "Hsap\CUL4B, Hsap\CUL4A, Hsap\CUL3" "cell lethalcell lethal,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,cell shape defective,decreased cell number,visible,partially lethal - majority die,some die during pupal stage,decreased cell death" "eye,somatic clone,follicle cell,mesothoracic tergum" DRSC07243 IE -1.020041778 -1.803892241 -0.672070867 -1.729769066 0.305541001 -0.442842379 FBgn0004780 Ccp84Ad Ccp84Ad http://flybase.org/reports/FBgn0004780 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular matrix ; GO:0031012 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "cc5, CG2341, BG:DS00004.4, Ccp84Ad, Ccp, DmelCcp84Ad" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2341 11-Aug-17 DroID_v2017_08 - - Cele\fbxb-38 - - - DRSC12589 E -0.440994131 0.96515886 -0.091688706 1.917354485 0.675927897 -0.119296188 FBgn0036607 CG13059 - http://flybase.org/reports/FBgn0036607 protein_coding_gene - - - CG13059 - CG13059 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC09942 K 0.381238094 -0.706746584 -0.337873852 -0.300640312 1.88276495 -0.215007721 FBgn0010348 Arf79F ADP ribosylation factor at 79F http://flybase.org/reports/FBgn0010348 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006689, InterPro:IPR024156 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity" synaptic vesicle endocytosis ; GO:0048488 | traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype post-Golgi vesicle-mediated transport ; GO:0006892 | inferred from mutant phenotype positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype regulation of hematopoietic stem cell differentiation ; GO:1902036 | inferred from mutant phenotype ARF protein signal transduction ; GO:0032011 | inferred from genetic interaction with garz endosomal transport ; GO:0016197 | traceable author statement cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | traceable author statement Golgi apparatus ; GO:0005794 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | colocalizes_with inferred from direct assay Golgi stack ; GO:0005795 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay "Dm Arf79F, ARF-1, Arf1, dARFI, ARF1, Darf1, CG8385, Arf79F, Arf, dARF79F, d-Arf1, dArf1, arf1, ARF1_DROME, Arf79f, P61209" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR024156:Small GTPase superfamily, ARF type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8385 11-Aug-17 DroID_v2017_08 "Drer\arl11, Drer\arl9, Drer\arl4ca, Drer\arl14, Drer\arf4a, Drer\arl5c, Drer\trim23, Drer\arl4cb, Drer\arf2b, Drer\si:ch1073-165f9.2, Drer\arl4aa, Drer\arl5a, Drer\arf3a, Drer\arf3b, Drer\zgc:77650, Drer\arl4d, Drer\arf5, Drer\zgc:110286, Drer\arf2a, Drer\arl6, Drer\arf1, Drer\arl4ab, Drer\arl8" "Scer\ARF2, Scer\ARF1" "Cele\arf-1.2, Cele\arf-3" "Xtro\arf5, Xtro\arl5a, Xtro\arf1, Xtro\arl11, Xtro\arl9, Xtro\arf3, Xtro\arl6, Xtro\arl5c, Xtro\trim23, Xtro\arl14, Xtro\arl5b, Xtro\arl4c, Xtro\arf4, Xtro\arl4a, Xtro\arl11" "Mmus\Arf3, Mmus\Arl11, Mmus\Arl5a, Mmus\Arl4a, Mmus\Arl5b, Mmus\Arf1, Mmus\Arl4d, Mmus\Arf5, Mmus\Arl9, Mmus\Arf2, Mmus\Arl6, Mmus\Trim23, Mmus\Arf4, Mmus\Arl5c, Mmus\Arl4c" "Hsap\ARL14, Hsap\ARL5B, Hsap\ARF5, Hsap\ARL11, Hsap\ARL9, Hsap\ARL6, Hsap\ARF3, Hsap\ARL4A, Hsap\ARF4, Hsap\ARL17B, Hsap\TRIM23, Hsap\ARL4C, Hsap\ARF1, Hsap\ARL5A, Hsap\ARL4D, Hsap\ARL17A, Hsap\ARL5C" adult stage "viable,fertile,lethal,cell cycle defective,endocytosis defective" "embryonic myoblast,rhabdomere R7,plasmatocyte | third instar larval stage,crystal cell | third instar larval stage,secondary lobe of embryonic/larval lymph gland | third instar larval stage,posterior signalling centre of lymph gland primary lobe | third instar larval stage,cortical zone of lymph gland primary lobe | third instar larval stage,embryonic/larval hemocyte | second instar larval stage,embryonic/larval hemocyte | third instar larval stage,posterior signalling centre of lymph gland primary lobe | first instar larval stage,posterior signalling centre of lymph gland primary lobe | second instar larval stage,lamellocyte,embryonic/larval hemocyte,eye" DRSC11606 E -0.757370785 0.09177419 0.930836857 -1.873575562 -0.489828235 -0.090853934 FBgn0020251 sfl sulfateless http://flybase.org/reports/FBgn0020251 FBgn0010820 protein_coding_gene [heparan sulfate]-glucosamine N-sulfotransferase activity ; GO:0015016 | inferred from electronic annotation with InterPro:IPR021930 hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR021930 [heparan sulfate]-glucosamine N-sulfotransferase activity ; GO:0015016 | traceable author statement sulfotransferase activity ; GO:0008146 | inferred from mutant phenotype "heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | non-traceable author statement heart development ; GO:0007507 | non-traceable author statement imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement intracellular distribution of mitochondria ; GO:0048312 | inferred from mutant phenotype regulation of decapentaplegic signaling pathway ; GO:0090097 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | traceable author statement segment polarity determination ; GO:0007367 | inferred from mutant phenotype glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q09147 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | traceable author statement cell surface receptor signaling pathway ; GO:0007166 | non-traceable author statement spermatogenesis ; GO:0007283 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q07407 sulfur compound metabolic process ; GO:0006790 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype regulation of canonical Wnt signaling pathway ; GO:0060828 | inferred from mutant phenotype regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay intracellular ; GO:0005622 | inferred by curator from GO:0048312 Golgi cis cisterna ; GO:0000137 | inferred from direct assay "sfl, NDST, CT24567, CG8339, dw, l(3)03844, sulfateless, Sfl, lincRNA.S4253" "IPR000863:Sulfotransferase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR021930:Heparan sulphate-N-deacetylase" CG8339 11-Aug-17 DroID_v2017_08 "Drer\ndst3, Drer\ndst2b, Drer\ndst2a, Drer\ndst1b, Drer\ndst1a" - Cele\hst-1 "Xtro\ndst4, Xtro\ndst1, Xtro\ndst2, Xtro\ndst3" "Mmus\Ndst1, Mmus\Ndst4, Mmus\Ndst2, Mmus\Ndst3" "Hsap\NDST2, Hsap\NDST1, Hsap\NDST3, Hsap\NDST4" embryonic stage | early "viable,fertile,lethal,recessive,fully,rescuable maternal effect,visible,somatic clone,increased mortality during development,neurophysiology defective,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,segment polarity phenotype,partially lethal - majority die,size defective" "embryonic/first instar larval cuticle,sensory mother cell,cuticle,denticle belt,mesoderm,germline clone,embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,embryonic/larval ganglionic branch,wing margin,somatic clone,synapse,imaginal tracheoblast,embryonic epidermis,stomatogastric nervous system,midgut constriction 2,embryo,mesothoracic tergum,anterior crossvein,wing disc" DRSC08830 K 1.357098144 1.139069118 0.443828557 -0.21373835 1.588698524 -0.311611419 FBgn0005778 PpD5 Protein phosphatase D5 http://flybase.org/reports/FBgn0005778 "FBgn0034682, FBgn0044777" protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with HGNC:9283 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with HGNC:9283 protein dephosphorylation ; GO:0006470 | non-traceable author statement nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:9283 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:9283 "CG10138, D5, anon-WO0140519.107, PpD5" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like, IPR031675:Serine-threonine protein phosphatase, N-terminal" CG10138 11-Aug-17 DroID_v2017_08 "Drer\ppp1cbl, Drer\ppp1cb" "Scer\GLC7, Scer\PPZ2, Scer\PPG1, Scer\PPQ1, Scer\PPZ1" "Cele\Y69E1A.4, Cele\pef-1, Cele\F23B12.1, Cele\ZK938.1, Cele\gsp-1, Cele\Y71G12B.30, Cele\F25B3.4, Cele\C34D4.2, Cele\C06A1.3, Cele\ZK354.9, Cele\T25B9.2, Cele\F22D6.9, Cele\F58G1.3, Cele\C30A5.4, Cele\pph-1, Cele\F52H3.6, Cele\R13A5.11" "Xtro\ppp1cb, Xtro\ppp1ca" "Mmus\Ppp1cb, Mmus\Ppef1" "Hsap\PPP1CB, Hsap\PPEF1" viable DRSC04641 I 1.609499959 -0.254151158 0.207311173 0.301575884 0.170236227 0.785042572 FBgn0031859 CG17377 - http://flybase.org/reports/FBgn0031859 protein_coding_gene - - - "CG17377, BEST:LP06279, anon-WO0140519.32" - CG17377 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Krtap5-5, Mmus\Sprr1a, Mmus\Krtap5-1" - DRSC21811 I 1.730693102 -1.899209258 0.79080497 0.4504855 0.171731521 0.525861543 FBgn0262111 f forked http://flybase.org/reports/FBgn0262111 protein_coding_gene actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN001192625 actin binding ; GO:0003779 | inferred from sequence or structural similarity sensory perception of sound ; GO:0007605 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype epidermal cell differentiation ; GO:0009913 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001192625 filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay "f, CG42864, CG5424, X1, CG12996" "IPR011990:Tetratricopeptide-like helical domain, IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG42864 11-Aug-17 DroID_v2017_08 "Drer\espnlb, Drer\espn, Drer\espnla" - "Cele\ipla-2, Cele\F13H8.1, Cele\ZK792.4, Cele\ipla-3" Xtro\espn "Mmus\Espnl, Mmus\Espn" "Hsap\ESPN, Hsap\ESPNL" " embryonic stage , pupal stage " DRSC20331 EK 0.442633592 -0.117204583 1.778375258 0.223447583 -1.545373741 -2.023087572 FBgn0028527 CG18507 - http://flybase.org/reports/FBgn0028527 protein_coding_gene - - - "bg:ds01368, DS01368.1, BG:DS01368.1, CG18507" IPR028054:Protein of unknown function DUF4481 CG18507 11-Aug-17 DroID_v2017_08 Drer\tmem268 - Cele\C26B9.1 - Mmus\Tmem268 Hsap\TMEM268 viable DRSC01334 K 0.05734465 -0.082186422 1.069166715 0.360276102 -1.625196689 1.347907389 FBgn0052070 CG32070 - http://flybase.org/reports/FBgn0052070 protein_coding_gene - - - CG32070 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC10148 IEK 0.223181158 -2.118598558 -1.258075065 -2.668143016 -1.862733662 -1.488758605 FBgn0011476 l(3)neo43 lethal (3) neo43 http://flybase.org/reports/FBgn0011476 FBgn0038314 protein_coding_gene - - mitochondrial membrane ; GO:0031966 | inferred from electronic annotation with InterPro:IPR020164 "CG14865, l(3)neo43" IPR020164:Cytochrome c oxidase assembly protein COX16 CG14865 11-Aug-17 DroID_v2017_08 "Drer\synj2bp, Drer\il16, Drer\si:dkey-121a11.3, Drer\cox16, Drer\pdzd2, Drer\si:ch211-13f8.1" Scer\COX16 "Cele\pqn-92, Cele\mics-1, Cele\Y75B8A.39, Cele\Y75B8A.28" Xtro\cox16 "Mmus\BC034090, Mmus\Pdzd2, Mmus\Synj2bp, Mmus\Cox16, Mmus\Synj2bp-cox16, Mmus\Il16" "Hsap\KIAA1614, Hsap\IL16, Hsap\SYNJ2BP, Hsap\COX16, Hsap\SYNJ2BP-COX16" "lethal,recessive,viable" DRSC14988 K 0.003641715 0.908018133 -0.73460815 0.067062258 0.546300075 -1.522109216 FBgn0010905 Spn Spinophilin http://flybase.org/reports/FBgn0010905 "FBgn0045360, FBgn0045813, FBgn0052295, FBgn0024370, FBgn0035350, FBgn0063195" protein_coding_gene neurexin family protein binding ; GO:0042043 | inferred from physical interaction with Nrx-1 olfactory behavior ; GO:0042048 | inferred from mutant phenotype negative regulation of presynaptic active zone assembly ; GO:1905519 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay "c62E-5, EL62, l(3)06911, E62, CG16757, BcDNA:GM16129, Spn, spn" "IPR013761:Sterile alpha motif/pointed domain, IPR001660:Sterile alpha motif domain, IPR001478:PDZ domain" CG16757 11-Aug-17 DroID_v2017_08 "Drer\cnksr1, Drer\ppp1r9a, Drer\ppp1r9ba, Drer\ppp1r9bb, Drer\si:ch1073-219n12.1, Drer\si:ch211-269i23.2, Drer\samd14, Drer\col7a1l" Scer\BOI1 "Cele\nab-1, Cele\C05D10.4" "Xtro\ppp1r9b, Xtro\ppp1r9a" "Mmus\Cnksr1, Mmus\Ppp1r9a, Mmus\Plekha5, Mmus\Samd14, Mmus\Ipcef1, Mmus\Pdzph1, Mmus\Ppp1r9b" "Hsap\PPP1R9B, Hsap\CNKSR1, Hsap\PPP1R9A, Hsap\SAMD14, Hsap\PLEKHA5" "behavior defective,recessive,viable,smell perception defective,partially lethal - majority die" DRSC08490 E 0.120464464 0.313313547 4.179139705 0.021906354 -0.865887499 0.174365904 FBgn0039404 CG14543 - http://flybase.org/reports/FBgn0039404 protein_coding_gene - "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000478716 neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000478716 CG14543 IPR019398:Pre-rRNA-processing protein TSR2 CG14543 11-Aug-17 DroID_v2017_08 Drer\tsr2 Scer\TSR2 Cele\Y51H4A.15 Xtro\tsr2 Mmus\Tsr2 Hsap\TSR2 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" DRSC26647 K -0.408115862 -0.993111832 0.891010119 -0.499351168 1.762681366 0.001220556 FBgn0022213 Cse1 Chromosome segregation 1 http://flybase.org/reports/FBgn0022213 "FBgn0027058, FBgn0027064" protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype protein export from nucleus ; GO:0006611 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay "CAS, dcas, Dcas, l(2)k03902, cas, CG13281, BcDNA:LD14270, Cas, Cse1" "IPR001494:Importin-beta, N-terminal domain, IPR005043:CAS/CSE, C-terminal, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR013713:Exportin/Importin, Cse1-like" CG13281 11-Aug-17 DroID_v2017_08 Drer\cse1l Scer\CSE1 Cele\xpo-2 Xtro\cse1l Mmus\Cse1l Hsap\CSE1L "lethal,recessive,somatic clone,female sterile,heat sensitive,wild-type,partially lethal - majority die,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,visible" "egg,microchaeta,macrochaeta,thecogen cell,eo neuron,tormogen cell,ectopic,embryonic/larval neuroblast,ganglion mother cell,tergite" DRSC03287 IEK -2.375873067 -2.443974 -0.865394335 -1.761913231 1.631364371 -0.286179869 FBgn0052080 CG32080 - http://flybase.org/reports/FBgn0052080 protein_coding_gene - - - CG32080 - - 11-Aug-17 DroID_v2017_08 - - - - - - DRSC09074 K -1.215343591 -0.162650678 -0.460372234 1.008727845 1.822830356 1.862328418 FBgn0051358 CG31358 - http://flybase.org/reports/FBgn0051358 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001972 "CG17424, CG18142, CG18141, CG31358" "IPR001107:Band 7 domain, IPR001972:Stomatin family" CG31358 11-Aug-17 DroID_v2017_08 "Drer\stom, Drer\nphs2, Drer\stoml3b, Drer\zgc:112408, Drer\stoml1, Drer\stoml3a" - "Cele\sto-1, Cele\unc-24, Cele\sto-6, Cele\sto-3, Cele\unc-1, Cele\sto-2, Cele\sto-5, Cele\mec-2, Cele\sto-4" "Xtro\stoml3, Xtro\stoml1" "Mmus\Stoml3, Mmus\Nphs2, Mmus\Stom, Mmus\Stoml1" "Hsap\STOML1, Hsap\STOM, Hsap\STOML3, Hsap\NPHS2" viable DRSC15308 E 0.197633403 1.425730584 1.801352901 0.205245976 -0.185364587 -0.237611095 FBgn0031249 CG11911 - http://flybase.org/reports/FBgn0031249 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP103, CG11911" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11911 11-Aug-17 DroID_v2017_08 - - - - "Mmus\Prss36, Mmus\Prtn3, Mmus\Prss53" "Hsap\AZU1, Hsap\PRSS36, Hsap\PRTN3, Hsap\PRSS53" viable DRSC27293 K -0.274163179 -0.33887127 -0.230535886 0.379632985 -0.677376771 -1.822196159 FBgn0033541 CG12934 - http://flybase.org/reports/FBgn0033541 protein_coding_gene - - - CG12934 - CG12934 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC06247 E -0.972267787 0.283259047 -0.498095649 2.148202277 1.050904829 0.399895067 FBgn0010053 Jheh1 Juvenile hormone epoxide hydrolase 1 http://flybase.org/reports/FBgn0010053 "FBgn0034404, FBgn0046304" protein_coding_gene cis-stilbene-oxide hydrolase activity ; GO:0033961 | inferred from electronic annotation with InterPro:IPR016292 juvenile hormone epoxide hydrolase activity ; GO:0008096 | inferred from direct assay juvenile hormone catabolic process ; GO:0006719 | inferred from direct assay - "142196_at, JHEH, Jheh, JH, CG15101, BEST:GH06241, Jheh1" "IPR000639:Epoxide hydrolase-like, IPR010497:Epoxide hydrolase, N-terminal, IPR016292:Epoxide hydrolase, IPR029058:Alpha/Beta hydrolase fold" CG15101 11-Aug-17 DroID_v2017_08 "Drer\ephx5, Drer\ephx1, Drer\ephx4" Scer\YNR064C "Cele\ZK896.4, Cele\C32H11.1, Cele\dod-17, Cele\ZK896.1, Cele\ZK896.5, Cele\C45B11.6, Cele\dod-22, Cele\ZK1037.6, Cele\dct-19, Cele\dod-24, Cele\C29F3.7, Cele\K10D11.2, Cele\C06B3.7, Cele\Y17D7B.3, Cele\F55G11.4, Cele\C49G7.7, Cele\C32H11.4, Cele\ceeh-2, Cele\K08D8.4, Cele\K08D8.6, Cele\T05E12.6, Cele\F55G11.8, Cele\K10D11.6, Cele\T19C9.8, Cele\K10D11.3, Cele\dod-21, Cele\ceeh-1, Cele\C49C3.9, Cele\K10D11.5, Cele\K10D11.7, Cele\W01A11.1, Cele\C06B3.6, Cele\K08D8.3, Cele\K10D11.4, Cele\F55G11.7, Cele\C32H11.3, Cele\irg-2, Cele\Y17D7B.2, Cele\K09D9.1, Cele\C32H11.9, Cele\F55G11.2, Cele\C49G7.10, Cele\C49G7.12, Cele\C45B11.2, Cele\K08D8.5, Cele\F17C11.11, Cele\F55G11.6, Cele\F55C9.6" Xtro\ephx1 "Mmus\Ephx2, Mmus\Ephx4, Mmus\Ephx1, Mmus\Ephx3" "Hsap\EPHX2, Hsap\EPHX4, Hsap\EPHX3, Hsap\EPHX1" "viable,fertile" DRSC06529 I 0.708921415 -1.95770292 -1.082711975 -0.088206565 -0.547520244 -0.69024549 FBgn0001104 Galphai G protein alpha i subunit http://flybase.org/reports/FBgn0001104 - protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001408 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCX1 protein binding ; GO:0005515 | inferred from physical interaction with loco protein binding ; GO:0005515 | inferred from physical interaction with pins G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W358 DNA binding ; GO:0003677 | inferred from direct assay G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from mutant phenotype calcium-mediated signaling ; GO:0019722 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from mutant phenotype establishment of endothelial blood-brain barrier ; GO:0014045 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | inferred from mutant phenotype establishment of spindle orientation ; GO:0051294 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype regulation of protein localization ; GO:0032880 | inferred from mutant phenotype axon ensheathment in central nervous system ; GO:0032291 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype cell cortex ; GO:0005938 | traceable author statement apical cortex ; GO:0045179 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay heterotrimeric G-protein complex ; GO:0005834 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 "Galphai, Galpha65A, Gai, Galpha[[i]], Gi, G-ia65A, G[[alphai]], Galpha i, Galpha[[i65A]], Gialpha, i, Gi-alpha, G[[i]]alpha, DG[[alpha1]], DGalpha1, G-ialpha65A, G-oalpha65A, G-alpha-65A, CG10060, Galphaiota65A, G[[i]], GNAI1/2/3, G-ialpha65a, Galpha[[i]]65A, Gi/0, Galphai/o, galphai" "IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR001408:G-protein alpha subunit, group I, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10060 11-Aug-17 DroID_v2017_08 "Drer\gna13b, Drer\gnat1, Drer\gnai3, Drer\gnat2, Drer\gna14, Drer\gnav1, Drer\gna12a, Drer\gnaz, Drer\gnaia, Drer\gnao1b, Drer\gnao1a, Drer\LOC797518, Drer\gna11a, Drer\gna15.1, Drer\gna15.2, Drer\gnaq, Drer\gnai1, Drer\gnai2a, Drer\gnai2b, Drer\gna13a" "Scer\GPA1, Scer\GPA2" "Cele\gpa-13, Cele\gpa-17, Cele\gpa-8, Cele\goa-1, Cele\gpa-15, Cele\odr-3, Cele\gpa-7, Cele\gpa-9, Cele\gpa-4, Cele\gpa-2, Cele\gpa-3, Cele\gpa-1, Cele\gpa-16, Cele\egl-30" "Xtro\gnai2, Xtro\gna14, Xtro\gna15, Xtro\gna11, Xtro\gnai1, Xtro\gna13, Xtro\gnat2, Xtro\gnat1, Xtro\gnai3, Xtro\gnao1, Xtro\gnaq" "Mmus\Gnat2, Mmus\Gna11, Mmus\Gna14, Mmus\Gnai1, Mmus\Gna15, Mmus\Gnai3, Mmus\Gnaq, Mmus\Gnao1, Mmus\Gnaz, Mmus\Gnat3, Mmus\Gna13, Mmus\Gna12, Mmus\Gnai2, Mmus\Gnat1" "Hsap\GNA13, Hsap\GNAT1, Hsap\GNAI2, Hsap\GNA14, Hsap\GNAI1, Hsap\GNAO1, Hsap\GNAT3, Hsap\GNAI3, Hsap\GNAZ, Hsap\GNA15, Hsap\GNAT2, Hsap\GNA12, Hsap\GNAQ, Hsap\GNA11" " embryonic stage | early--P , adult stage && oogenesis stage , embryonic stage , embryonic stage&&pupal stage , embryonic stage -- adult stage " " organism

, oocyte

, nurse cell

" " larval stage , adult stage , embryonic stage | pre-blastoderm , embryonic stage | stage >=14 , adult stage && oogenesis stage | stage >=S10B , embryonic stage | >stage 15 " " subesophageal ganglion | restricted

, nerve terminal &&of photoreceptor cell

, organism

, ocellar nerve | proximal

, cardioblast | presumptive

, follicle cell

, ring gland

, neuropil

, cardioblast

, antennal glomerulus

, retina

, adult brain cortex

, ocellus retinula cell

" "cell polarity defective,planar polarity defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,viable,fertile,wild-type,germline clone,locomotor behavior defective" "embryonic neuroblast & spindlemat.‘±Tub67C.THsimVP16,embryonic neuroblast,sensory mother cell & spindle-109-68,medial triple row,lateral cord surface glia & nucleusrepo,cell cortex & cortical cytoskeletonrepo,neuroblast,spindle pole centrosome & astral microtubule-P309,mitotic domain 9 & epithelial cell,RP2sib neuron,RP2 motor neuron,spindle & neuroblast,germline clone,EL neuron,spindle & external sensory organ precursor cell I,chaeta" FBgn0015778 rin rasputin http://flybase.org/reports/FBgn0015778 FBgn0038164 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with lig mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000074904 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR002075 Ras protein signal transduction ; GO:0007265 | inferred from genetic interaction with Rho1 negative regulation of imaginal disc growth ; GO:0045571 | inferred from genetic interaction with lig inferred from genetic interaction with Fmr1 inferred from genetic interaction with Capr mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype inferred from genetic interaction with orb ommatidial rotation ; GO:0016318 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | colocalizes_with inferred from physical interaction with orb "CG9412, cg9412, rasp, Nts, rin, Rin, RIN" "IPR018222:Nuclear transport factor 2, eukaryote, IPR000504:RNA recognition motif domain, IPR002075:Nuclear transport factor 2, IPR032710:NTF2-like domain" CG9412 11-Aug-17 DroID_v2017_08 "Drer\g3bp2, Drer\g3bp1, Drer\zgc:56304" Scer\BRE5 Cele\gtbp-1 "Xtro\g3bp2, Xtro\g3bp1" "Mmus\G3bp1, Mmus\G3bp2" "Hsap\G3BP2, Hsap\G3BP1" " embryonic stage--pupal stage , adult stage | female " " embryonic stage -- adult stage , larval stage | third instar " " eye disc

, photoreceptor cell | precursor

" "lethal,recessive,viable,fertile,visible,planar polarity defective,wild-type,size defective,somatic clone,sterile,lethal - all die before end of pupal stage,some die during pupal stage" "eye,ommatidium,eye photoreceptor cell,eye disc,somatic clone,supernumerary,wing,ommatidial precursor cluster" DRSC22997 K 2.35833026 0.798363735 FBgn0000173 ben bendless http://flybase.org/reports/FBgn0000173 FBgn0066817 protein_coding_gene ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with Uev1A ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with nopo ubiquitin conjugating enzyme activity ; GO:0061631 | contributes_to inferred from direct assay ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity "synapse maturation ; GO:0060074 | inferred from mutant phenotype response to anesthetic ; GO:0072347 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype grooming behavior ; GO:0007625 | traceable author statement grooming behavior ; GO:0007625 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype protein K63-linked ubiquitination ; GO:0070534 | inferred from biological aspect of ancestor with PANTHER:PTN000630262 positive regulation of mitotic cell cycle, embryonic ; GO:0045977 | inferred from mutant phenotype jump response ; GO:0007630 | inferred from mutant phenotype axon target recognition ; GO:0007412 | inferred from mutant phenotype positive regulation of cell death ; GO:0010942 | inferred from genetic interaction with egr positive regulation of JNK cascade ; GO:0046330 | inferred from genetic interaction with hep inferred from genetic interaction with Tak1 inferred from genetic interaction with egr inferred from genetic interaction with Traf6 inferred from physical interaction with Traf6 positive regulation of protein polyubiquitination ; GO:1902916 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype postreplication repair ; GO:0006301 | inferred from biological aspect of ancestor with PANTHER:PTN000630262 protein polyubiquitination ; GO:0000209 | inferred from direct assay response to oxidative stress ; GO:0006979 | inferred from mutant phenotype" perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay UBC13-UEV1A complex ; GO:0035370 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Ben, UbcD3, nj-262, CG18319, anon-WO03040301.242, ben, Ubc13, ubc13, BEN, UBC13, Bend" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG18319 11-Aug-17 DroID_v2017_08 "Drer\ube2e1, Drer\ube2d1a, Drer\ube2d2, Drer\ube2d1b, Drer\ube2e3, Drer\ube2e2, Drer\ube2d3, Drer\ube2nb, Drer\ube2d4, Drer\ube2t, Drer\ube2na" "Scer\UBC13, Scer\UBC5, Scer\UBC4, Scer\PEX4" "Cele\uev-3, Cele\ubc-13" "Xtro\ube2n, Xtro\ube2d1, Xtro\ube2e1, Xtro\ube2d4, Xtro\ube2e3, Xtro\ube2e2, Xtro\ube2d3" "Mmus\Ube2n, Mmus\Ube2e1, Mmus\Ube2dnl1, Mmus\Ube2d1, Mmus\Ube2t, Mmus\Ube2e2, Mmus\Ube2e3, Mmus\Ube2d3, Mmus\Ube2dnl2, Mmus\Ube2d2b" "Hsap\UBE2E2, Hsap\UBE2E3, Hsap\UBE2E1, Hsap\UBE2D1, Hsap\UBE2D3, Hsap\UBE2T, Hsap\UBE2D4, Hsap\UBE2NL, Hsap\UBE2N, Hsap\UBE2D2" " larval stage | third instar , pupal stage && adult stage , embryonic stage | >= stage 11 , embryonic stage | stage >=11 " " larval muscle system

, retina

, ventral nerve cord

, supraesophageal ganglion

, embryonic/larval digestive system

, imaginal disc

, peripheral nervous system

, subesophageal ganglion

, thoracico-abdominal ganglion

, embryonic/larval salivary gland

, embryonic central nervous system | presumptive

, proventriculus

" "locomotor behavior defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage,wild-type,jumping defective,behavior defective,neuroanatomy defective,lethal,partially,uncoordinated,grooming behavior defective,neurophysiology defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,visible,partially lethal - majority die,some die during pharate adult stage,chemical sensitive" "photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,optic cartridge,giant fiber neuron,mesothoracic extracoxal depressor muscle 66,lateral oblique dorsal muscle,tergosternal muscle,coxal tergal remotor muscle,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,rhabdomere R7,retina,lamina anlage,medulla anlage,rhabdomere R8,photoreceptor cell R1,photoreceptor cell R2,tergotrochanteral muscle motor neuron,gap junction,synapse,centrosome | non-rescuable maternal effect,spindle | non-rescuable maternal effect,centrosome | non-rescuable maternal effectKA10),spindle | non-rescuable maternal effectKA10),chaeta,supernumerary,mesothoracic tergum" DRSC20310 I 2.293546016 -0.365465392 0.387234022 0.176879289 0.435776254 -0.182533417 FBgn0263111 cac cacophony http://flybase.org/reports/FBgn0263111 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 voltage-gated calcium channel activity ; GO:0005245 | inferred from mutant phenotype voltage-gated calcium channel activity ; GO:0005245 | inferred from direct assay low voltage-gated calcium channel activity ; GO:0008332 | inferred from mutant phenotype voltage-gated calcium channel activity ; GO:0005245 | non-traceable author statement high voltage-gated calcium channel activity ; GO:0008331 | inferred from mutant phenotype "male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype visual behavior ; GO:0007632 | non-traceable author statement calcium-mediated signaling ; GO:0019722 | inferred from mutant phenotype positive regulation of calcium ion transport into cytosol ; GO:0010524 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | traceable author statement neuron remodeling ; GO:0016322 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from direct assay male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement calcium ion transport ; GO:0006816 | non-traceable author statement regulation of heart rate ; GO:0002027 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype calcium ion transmembrane transport ; GO:0070588 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from genetic interaction with GluRIIA, Exn courtship behavior ; GO:0007619 | non-traceable author statement epithelial fluid transport ; GO:0042045 | inferred from expression pattern inferred from direct assay adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype phototransduction ; GO:0007602 | non-traceable author statement courtship behavior ; GO:0007619 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from genetic interaction with comt regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from genetic interaction with Ih membrane depolarization during action potential ; GO:0086010 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 neurotransmitter secretion ; GO:0007269 | NOT inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype" neuromuscular junction ; GO:0031594 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay voltage-gated calcium channel complex ; GO:0005891 | non-traceable author statement basolateral plasma membrane ; GO:0016323 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay voltage-gated calcium channel complex ; GO:0005891 | inferred from genetic interaction with Ca-α1D presynaptic active zone ; GO:0048786 | "DMCA1A, Dmca1A, Cac, CG43368, cac, CAC, CG1522, nbA, alpha1A, Dmcalpha1A, l(1)13, l(1)L13, L13, 13, nonB, opm47, opm18, ldg, l(1)11Aa, P18, H47, H18, EE171, Ca-alpha1A, Ca[[V]]2.1, cac1, CG15928, Cac1, dCac1" "IPR002048:EF-hand domain, IPR014873:Voltage-dependent calcium channel, alpha-1 subunit, IQ domain, IPR002077:Voltage-dependent calcium channel, alpha-1 subunit, IPR005821:Ion transport domain, IPR005446:Voltage-dependent calcium channel, L-type, alpha-1 subunit, IPR031649:Voltage-dependent L-type calcium channel, IQ-associated domain" CG43368 11-Aug-17 DroID_v2017_08 "Drer\cacna1da, Drer\cacna1e, Drer\gb:eh507706, Drer\cacna1sb, Drer\scn8aa, Drer\cacna1bb, Drer\cacna1fa, Drer\cacna1aa, Drer\cacna1ba, Drer\cacna1ab, Drer\nalcn, Drer\cacna1eb, Drer\cacna1fb, Drer\cacna1sa, Drer\cacna1c" Scer\CCH1 "Cele\nca-2, Cele\unc-77, Cele\unc-2, Cele\egl-19" "Xtro\cacna1f, Xtro\cacna1d, Xtro\cacna1s, Xtro\scn2a, Xtro\scn1a, Xtro\cacna1e, Xtro\cacna1a" "Mmus\Catsper1, Mmus\Scn4a, Mmus\Cacna1s, Mmus\Cacna1c, Mmus\Cacna1d, Mmus\Cacna1f, Mmus\Cacna1e, Mmus\Scn8a, Mmus\Cacna1a, Mmus\Nalcn, Mmus\Cacna1b, Mmus\Scn1a" "Hsap\NALCN, Hsap\CACNA1E, Hsap\SCN2A, Hsap\CACNA1F, Hsap\CACNA1A, Hsap\CATSPER1, Hsap\SCN8A, Hsap\CACNA1S, Hsap\CACNA1B, Hsap\CACNA1D, Hsap\CACNA1C, Hsap\SCN1A, Hsap\SCN4A" " pupal stage , larval stage , embryonic stage " embryonic central nervous system

FBgn0261612 CngA Cyclic nucleotide-gated ion channel subunit A http://flybase.org/reports/FBgn0261612 protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 intracellular cyclic nucleotide activated cation channel activity ; GO:0005221 | inferred from direct assay "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 cation transport ; GO:0006812 | inferred from direct assay cGMP-mediated signaling ; GO:0019934 | traceable author statement cGMP-mediated signaling ; GO:0019934 | inferred from direct assay response to hypoxia ; GO:0001666 | inferred from mutant phenotype inferred from genetic interaction with Gyc89Da, Gyc89Db regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000025348" intracellular cyclic nucleotide activated cation channel complex ; GO:0017071 | inferred from direct assay intracellular cyclic nucleotide activated cation channel complex ; GO:0017071 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 "CG42701, cng, DmCNGC, CNG, dCNCalpha, CG7779, CG15709, dmCNGA, CngA, Cng, DmCNGA" "IPR000595:Cyclic nucleotide-binding domain, IPR005821:Ion transport domain, IPR018488:Cyclic nucleotide-binding, conserved site, IPR018490:Cyclic nucleotide-binding-like, IPR014710:RmlC-like jelly roll fold, IPR032406:Cyclic nucleotide-gated channel, C-terminal leucine zipper domain" CG42701 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-22i16.2, Drer\cnga1, Drer\cngb1a, Drer\LOC100334711, Drer\cnga5, Drer\cnga3a, Drer\LOC103911065, Drer\cngb3.1, Drer\cnga4" - "Cele\cng-3, Cele\tax-4, Cele\che-6, Cele\tax-2, Cele\cng-2, Cele\cng-1" "Xtro\cngb3, Xtro\cngb1, Xtro\cnga3, Xtro\cnga1, Xtro\cnga4" "Mmus\Cnga3, Mmus\Cnga2, Mmus\Cnga1, Mmus\Cngb1, Mmus\Cnga4, Mmus\Cngb3" "Hsap\CNGA4, Hsap\CNGB1, Hsap\CNGA1, Hsap\CNGA2, Hsap\CNGA3, Hsap\CNGB3" DRSC06580 E -0.717067805 -1.47957896 0.799212727 -2.828000572 -1.34443183 -0.008155526 FBgn0265139 Gr2a Gustatory receptor 2a http://flybase.org/reports/FBgn0265139 protein_coding_gene taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity non-traceable author statement G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity non-traceable author statement sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr2a, GR2a, Gr2B1, CG18531, GR2B1, EG:BACN32G11.1, Gr1F1, GR1F.1" IPR013604:7TM chemoreceptor CG18531 11-Aug-17 DroID_v2017_08 - - "Cele\lite-1, Cele\gur-3" - - - DRSC18603 I 2.003528084 0.78280471 -0.012384935 0.199504004 -0.305902663 -0.220138543 FBgn0264542 hwt heavyweight http://flybase.org/reports/FBgn0264542 protein_coding_gene SH3/SH2 adaptor activity ; GO:0005070 | inferred from biological aspect of ancestor with PANTHER:PTN001031645 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001031645 regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "lincRNA.981, CG15729, CG32653, CG42251, CG11146, BcDNA:GH02424, 43921, hwt, CG43921" "IPR000980:SH2 domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR011011:Zinc finger, FYVE/PHD-type" CG43921 11-Aug-17 DroID_v2017_08 "Drer\zgc:158464, Drer\shda, Drer\she, Drer\shdb" - - "Xtro\shb, Xtro\shf, Xtro\she, Xtro\shd" "Mmus\Shd, Mmus\Shf, Mmus\Shb, Mmus\She" "Hsap\SHB, Hsap\SHF, Hsap\SHE, Hsap\SHD" DRSC19386 I 1.398505464 2.419797462 -0.519811268 0.180595291 -0.264638157 0.351990782 FBgn0037147 CG7140 - http://flybase.org/reports/FBgn0037147 protein_coding_gene "glucose-6-phosphate dehydrogenase activity ; GO:0004345 | inferred from electronic annotation with InterPro:IPR001282, InterPro:IPR022674, InterPro:IPR022675 NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR022674, InterPro:IPR022675" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001282, InterPro:IPR022674, InterPro:IPR022675 glucose metabolic process ; GO:0006006 | inferred from electronic annotation with InterPro:IPR001282, InterPro:IPR022674, InterPro:IPR022675" - CG7140 "IPR001282:Glucose-6-phosphate dehydrogenase, IPR016040:NAD(P)-binding domain, IPR022674:Glucose-6-phosphate dehydrogenase, NAD-binding, IPR022675:Glucose-6-phosphate dehydrogenase, C-terminal" CG7140 11-Aug-17 DroID_v2017_08 "Drer\h6pd, Drer\g6pd" Scer\ZWF1 Cele\gspd-1 Xtro\h6pd "Mmus\G6pd2, Mmus\H6pd, Mmus\G6pdx" "Hsap\G6PD, Hsap\H6PD" viable DRSC11799 IK 1.531538202 0.41334096 0.720769912 0.154602791 5.091044796 0.867216785 FBgn0260798 Gprk1 G protein-coupled receptor kinase 1 http://flybase.org/reports/FBgn0260798 protein_coding_gene G-protein coupled receptor kinase activity ; GO:0004703 | inferred from electronic annotation with InterPro:IPR000239 ATP binding ; GO:0005524 | inferred from mutant phenotype rhodopsin kinase activity ; GO:0050254 | inferred from mutant phenotype protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement phosphatidylinositol binding ; GO:0035091 | inferred from direct assay G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with ninaE G-protein coupled receptor kinase activity ; GO:0004703 | inferred from sequence or structural similarity "metarhodopsin inactivation ; GO:0016060 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement signal transduction ; GO:0007165 | inferred from sequence or structural similarity phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from genetic interaction with Gprk2" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with Gprk2 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with Gprk2 "RK, gprk1, Gprk-1, GPRK1, CT4320, CG40129, Gprk1, Rok" "IPR000239:GPCR kinase, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR001849:Pleckstrin homology domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011993:PH domain-like, IPR016137:RGS domain, IPR017441:Protein kinase, ATP binding site" CG40129 11-Aug-17 DroID_v2017_08 "Drer\grk5l, Drer\grk4, Drer\grk1a, Drer\grk7a, Drer\grk5, Drer\grk7b, Drer\grk6, Drer\adrbk2, Drer\grk1b" - Cele\grk-2 "Xtro\grk7, Xtro\grk4, Xtro\grk6, Xtro\adrbk2, Xtro\grk1, Xtro\grk5" "Mmus\Grk3, Mmus\Grk5, Mmus\Grk1, Mmus\Grk4, Mmus\Grk2, Mmus\Grk6" "Hsap\GRK3, Hsap\GRK4, Hsap\GRK2, Hsap\GRK1, Hsap\GRK6, Hsap\GRK5, Hsap\GRK7" " embryonic stage -- adult stage , adult stage " "

ubiquitous , adult head

, retina

" DRSC20916 E -1.499315262 0.218449214 2.829835308 0.147172947 0.277244131 -0.343837774 FBgn0038829 CG17271 - http://flybase.org/reports/FBgn0038829 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium ion binding ; GO:0005509 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG17271, Dm_3R:88623" "IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain" CG17271 11-Aug-17 DroID_v2017_08 "Drer\cgref1, Drer\mcfd2" - "Cele\F55A11.1, Cele\T04F3.4, Cele\C29E4.14" Xtro\mcfd2 "Mmus\Cgref1, Mmus\Mcfd2" "Hsap\CGREF1, Hsap\MCFD2" DRSC22982 K 1.852299824 -0.290755036 FBgn0014163 fax failed axon connections http://flybase.org/reports/FBgn0014163 "FBgn0025997, FBgn0046364, FBgn0046365, FBgn0046366, FBgn0046367, FBgn0046368, FBgn0046369, FBgn0046370" protein_coding_gene - axonogenesis ; GO:0007409 | inferred from genetic interaction with Abl axonogenesis ; GO:0007409 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "Fax, fac, anon-EST:Liang-1.34, clone 1.34, CG4609, anon-WO0172774.69, anon-WO0172774.68, anon-WO0172774.67, anon-WO0172774.66, anon-WO0172774.65, anon-WO0172774.63, anon-WO0172774.62, fax" "IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold, IPR026928:Failed axon connections, IPR033468:Metaxin, glutathione S-transferase domain" CG4609 11-Aug-17 DroID_v2017_08 "Drer\mtx2, Drer\faxcb, Drer\faxca" - "Cele\F53G12.9, Cele\C25H3.7, Cele\cdr-2, Cele\cdr-6, Cele\hrg-2, Cele\cdr-3, Cele\cdr-7, Cele\mtx-2, Cele\Y48C3A.3, Cele\cdr-1, Cele\cdr-4, Cele\Y57A10A.26" "Xtro\faxc, Xtro\mtx2" "Mmus\Faxc, Mmus\Mtx2" "Hsap\MTX2, Hsap\FAXC" embryonic stage " central nervous system

, embryonic peripheral nervous system

, visceral mesoderm

, ectoderm

" pupal stage "lethal,viable,fertile,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" DRSC11345 E -0.7142763 -0.126032227 2.983554487 -1.267297315 -1.444336234 -0.124981293 FBgn0030358 CG10362 - http://flybase.org/reports/FBgn0030358 protein_coding_gene - intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 - CG10362 "IPR001478:PDZ domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain" CG10362 11-Aug-17 DroID_v2017_08 Drer\pdzd8 - Cele\C53B4.4 - Mmus\Pdzd8 Hsap\PDZD8 viable DRSC19355 I 1.014027316 1.766324589 1.072909367 1.254088485 -1.031452762 -1.14521692 FBgn0013762 Cdk5 Cyclin-dependent kinase 5 http://flybase.org/reports/FBgn0013762 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from direct assay cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity" axonogenesis ; GO:0007409 | inferred from mutant phenotype inferred from genetic interaction with Cdk5α centrosome localization ; GO:0051642 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ; GO:0070059 | inferred from genetic interaction with ninaE protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay neuron apoptotic process ; GO:0051402 | inferred from biological aspect of ancestor with PANTHER:PTN000623852 regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from biological aspect of ancestor with PANTHER:PTN000623852 flight behavior ; GO:0007629 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype synaptic vesicle transport ; GO:0048489 | inferred from biological aspect of ancestor with PANTHER:PTN000623852 cyclin-dependent protein kinase 5 holoenzyme complex ; GO:0016533 | inferred from physical interaction with Cdk5α cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000623701 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 "CDK5, CG8203, cdk5, DmCdk5, Cdk5" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG8203 11-Aug-17 DroID_v2017_08 "Drer\cdk4, Drer\cdk14, Drer\cdk15, Drer\si:dkey-166c18.1, Drer\LOC100536316, Drer\cdk16, Drer\cdk2, Drer\cdk1, Drer\cdk17, Drer\cdk21, Drer\cdk5, Drer\cdk6" "Scer\PHO85, Scer\CDC28, Scer\CAK1" "Cele\cdk-5, Cele\ZC123.4, Cele\T07F12.4, Cele\cdk-1" "Xtro\cdk4, Xtro\cdk14, Xtro\cdk15, Xtro\cdk1, Xtro\cdk17, Xtro\cdk18, Xtro\cdk16, Xtro\cdk6, Xtro\cdk2, Xtro\cdk5" "Mmus\Cdk16, Mmus\Cdk1, Mmus\E030030I06Rik, Mmus\Cdk17, Mmus\Cdk18, Mmus\Cdk6, Mmus\Cdk5, Mmus\Cdk14, Mmus\Cdk2, Mmus\Cdk4, Mmus\Cdk15" "Hsap\CDK14, Hsap\CDK17, Hsap\CDK1, Hsap\CDK4, Hsap\CDK3, Hsap\CDK18, Hsap\CDK16, Hsap\CDK5, Hsap\CDK6, Hsap\CDK15, Hsap\CDK2" " embryonic stage -- adult stage , embryonic stage , embryonic stage | early " " embryonic central nervous system

,

ubiquitous , embryonic nervous system

" embryonic stage "neuroanatomy defective,short lived,viable" "presumptive embryonic/larval nervous system,motor neuron | embryonic stage,centrosomeneur-P72,external sensory organ precursor cell I" DRSC07359 K -0.12850455 0.8502728 -0.457304959 1.248809064 -1.570280512 0.36863823 FBgn0028394 CG17834 - http://flybase.org/reports/FBgn0028394 protein_coding_gene - - - "anon-29Da, BcDNA:LP07538, CG17834, anon-290a" - CG17834 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC26694 K -0.609900066 0.400672533 -0.110439607 -0.347384476 2.40024301 -0.110756412 FBgn0260972 alc alicorn http://flybase.org/reports/FBgn0260972 protein_coding_gene - signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR030080 regulation of protein kinase activity ; GO:0045859 | inferred from electronic annotation with InterPro:IPR030080 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype maintenance of apical/basal cell polarity ; GO:0035090 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype nucleotide-activated protein kinase complex ; GO:0031588 | inferred from electronic annotation with InterPro:IPR030080 "CG8057, AMPKbeta, alicorn, FBgn0033383, alc, betaAMPK, l(2)45Ad, 8057" "IPR014756:Immunoglobulin E-set, IPR006828:Association with the SNF1 complex (ASC) domain, IPR013783:Immunoglobulin-like fold, IPR030080:5'-AMP-activated protein kinase subunit beta-1, IPR032640:AMP-activated protein kinase, glycogen-binding domain" CG8057 11-Aug-17 DroID_v2017_08 "Drer\prkab2, Drer\prkab1b, Drer\prkab1a" "Scer\MDG1, Scer\GAL83, Scer\SIP1, Scer\SIP2, Scer\CRP1" "Cele\aakb-1, Cele\C01F6.2, Cele\aakb-2" "Xtro\prkab1, Xtro\prkab2" "Mmus\Prkab1, Mmus\Prkab2" "Hsap\PRKAB1, Hsap\PRKAB2" DRSC23316 K 0.292159797 -0.194127059 0.383416781 0.224513617 -1.548638228 0.259849654 FBgn0032493 Mabi Mabiki http://flybase.org/reports/FBgn0032493 protein_coding_gene - positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype - "CG15479, Mabi, DM2" - CG15479 11-Aug-17 DroID_v2017_08 "Drer\cebpa, Drer\cebp1, Drer\cebpb, Drer\cebpd" - "Cele\cebp-1, Cele\zip-4, Cele\zip-8" - "Mmus\Cebpb, Mmus\Cebpe, Mmus\Cebpa, Mmus\Cebpd" "Hsap\CEBPE, Hsap\CEBPD, Hsap\CEBPA, Hsap\CEBPB" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC02489 K -0.343061898 0.110131053 0.514082962 0.736899366 2.25434361 -0.43078193 FBgn0050481 mRpL53 mitochondrial ribosomal protein L53 http://flybase.org/reports/FBgn0050481 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000004838 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with SGD:S000004838 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CG33184, BcDNA:GM05817, CG30481, mRpL53" "IPR019716:Ribosomal protein L53, mitochondrial" CG30481 11-Aug-17 DroID_v2017_08 Drer\mrpl53 - Cele\mrpl-53 Xtro\mrpl53 Mmus\Mrpl53 Hsap\MRPL53 DRSC05461 E -0.725184896 -0.022961527 -1.684957584 0.207115676 0.085532898 -0.201633316 FBgn0039877 CG2118 - http://flybase.org/reports/FBgn0039877 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR005479, InterPro:IPR011761, InterPro:IPR011764, InterPro:IPR013815, InterPro:IPR013816 biotin carboxylase activity ; GO:0004075 | inferred from electronic annotation with InterPro:IPR011764 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011761 methylcrotonoyl-CoA carboxylase activity ; GO:0004485 | inferred from sequence or structural similarity with UniProtKB:Q96RQ3" leucine metabolic process ; GO:0006551 | inferred from sequence or structural similarity with UniProtKB:Q96RQ3 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q96RQ3 "MCC, CG2118, mcc, Q9V9T5_DROME" "IPR000089:Biotin/lipoyl attachment, IPR001882:Biotin-binding site, IPR005479:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain, IPR005481:Biotin carboxylase-like, N-terminal domain, IPR005482:Biotin carboxylase, C-terminal, IPR011053:Single hybrid motif, IPR011054:Rudiment single hybrid motif, IPR011761:ATP-grasp fold, IPR011764:Biotin carboxylation domain, IPR016185:Pre-ATP-grasp domain, IPR013815:ATP-grasp fold, subdomain 1" CG2118 11-Aug-17 DroID_v2017_08 "Drer\mccc1, Drer\pcca, Drer\pcxb" "Scer\PYC1, Scer\DUR1,2, Scer\PYC2" "Cele\pcca-1, Cele\pyc-1, Cele\mccc-1" "Xtro\mccc1, Xtro\pcca" "Mmus\Mccc1, Mmus\Pcca, Mmus\Pcx" "Hsap\MCCC1, Hsap\PC, Hsap\PCCA" "heat stress response defective,viable,fertile" DRSC27491 K 0.120019048 0.068028642 -0.091474112 0.829743229 0.492344492 -2.041524452 FBgn0019650 toy twin of eyeless http://flybase.org/reports/FBgn0019650 FBgn0004523 protein_coding_gene "RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from mutant phenotype transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay ocellus development ; GO:0008056 | inferred from mutant phenotype inferred from genetic interaction with oc positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement mushroom body development ; GO:0016319 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype - "twin of eyeless, Toy, l(4)102CDg, l(4)8, CG11186, toy, Pax-6, TOY" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG11186 11-Aug-17 DroID_v2017_08 "Drer\shox, Drer\hoxd3a, Drer\pax6b, Drer\pax3a, Drer\pax10, Drer\pax2b, Drer\gsc, Drer\pax5, Drer\hoxb3a, Drer\arxb, Drer\pax3b, Drer\hoxb8a, Drer\pitx3, Drer\ldb3a, Drer\pax9, Drer\hhex, Drer\dmbx1a, Drer\hoxa3a, Drer\pax7a, Drer\mxtx2, Drer\pdlim7, Drer\pax1b, Drer\pax6a, Drer\arxa, Drer\lhx6, Drer\pax1a, Drer\pax8, Drer\pax4, Drer\pax7b, Drer\pax2a, Drer\mxtx1, Drer\pdlim3b, Drer\pitx1, Drer\mixl1, Drer\shox2, Drer\dmbx1b" "Scer\YHP1, Scer\PXL1, Scer\YOX1, Scer\PHO2" "Cele\ceh-51, Cele\alp-1, Cele\pax-1, Cele\vab-3, Cele\lim-4, Cele\pax-2, Cele\egl-38, Cele\alr-1, Cele\ceh-45" "Xtro\pax3, Xtro\arx, Xtro\pax1, Xtro\pax7, Xtro\pax5, Xtro\pdlim5, Xtro\pax2, Xtro\pitx3, Xtro\pax6, Xtro\mix1, Xtro\hoxd3, Xtro\pax9, Xtro\sia1, Xtro\hoxb8, Xtro\bix1.1, Xtro\mixer, Xtro\hoxb3, Xtro\shox2, Xtro\pax8, Xtro\pitx1, Xtro\lhx8, Xtro\gsc" "Mmus\Pitx3, Mmus\Cphx3, Mmus\Gsc2, Mmus\Duxbl3, Mmus\Pdlim7, Mmus\Pax5, Mmus\Pdlim3, Mmus\Duxbl1, Mmus\Pax3, Mmus\Gsc, Mmus\Pdlim1, Mmus\Pax4, Mmus\Pax6, Mmus\Dmbx1, Mmus\Pdlim5, Mmus\Hoxc5, Mmus\Lhx5, Mmus\Pax9, Mmus\Arx, Mmus\Cphx1, Mmus\Mixl1, Mmus\Lhx6, Mmus\Pax8, Mmus\Lhx8, Mmus\Pax7, Mmus\Shox2, Mmus\Hoxb5, Mmus\Pitx1, Mmus\Pax2, Mmus\Duxbl2, Mmus\Pax1, Mmus\Ldb3, Mmus\Hoxa3" "Hsap\GSC2, Hsap\HOXA3, Hsap\DUXA, Hsap\PAX9, Hsap\GBX1, Hsap\PAX2, Hsap\MIXL1, Hsap\SHOX2, Hsap\DMBX1, Hsap\GSC, Hsap\PAX3, Hsap\PAX6, Hsap\PDLIM3, Hsap\SHOX, Hsap\LHX8, Hsap\PAX4, Hsap\PITX1, Hsap\DUX4, Hsap\HOXC5, Hsap\LPXN, Hsap\LHX5, Hsap\LDB3, Hsap\PAX8, Hsap\LHX6, Hsap\PAX7, Hsap\ARX, Hsap\PAX5, Hsap\PDLIM1, Hsap\PDLIM7, Hsap\PAX1, Hsap\PITX3, Hsap\HOXB8" " embryonic stage | stage 9-11 , embryonic stage -- adult stage , larval stage--adult stage " " protocerebral neuroblast | subset

, procephalic neurogenic region && embryonic ocular segment | restricted

, deuterocerebral neuroblast | subset

, procephalic neurogenic region && embryonic antennal segment | restricted

" embryonic stage | stage 9-11 " procephalic neurogenic region && embryonic antennal segment | restricted

, procephalic neurogenic region && embryonic ocular segment | restricted

, protocerebral neuroblast | subset

, deuterocerebral neuroblast | subset

" "wild-type,lethal,recessive,partially,heat sensitive,neuroanatomy defective,partially lethal - majority die,increased cell death,lethal - all die before end of P-stage,some die during pharate adult stage,visible,lethal - all die before end of larval stage,some die during larval stage,viable" "head,eye-antennal disc,embryonic brain,commissure,embryonic/larval brain,adult head,ocellus,adult mushroom body,eye disc,eye,ectopic,leg & eye | ectopicdpp.blk1,wing & eye | ectopicdpp.blk1,leg,wing,antenna,heat sensitive,vertical lobe of adult mushroom body" DRSC17222 I -0.98393883 -1.978601124 0.596112083 -0.7851539 0.52323579 -0.080911847 FBgn0004880 scrt scratch http://flybase.org/reports/FBgn0004880 "FBgn0064785, FBgn0066002" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype - "clone 1.67, clone 1.31, anon-EST:Liang-1.67, anon-EST:Liang-1.31, CG1130, BcDNA:RH71479, anon-WO02059370.57, scrt, Scrt, lincRNA.S4061" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1130 11-Aug-17 DroID_v2017_08 "Drer\zbtb16a, Drer\snai2, Drer\scrt1a, Drer\snai1b, Drer\snai1a, Drer\zbtb7a, Drer\zbtb7c, Drer\snai3, Drer\scrt2, Drer\scrt1b" "Scer\MET32, Scer\AZF1" "Cele\Y111B2A.10, Cele\snai-1, Cele\ces-1, Cele\scrt-1" "Xtro\wt1, Xtro\snai1, Xtro\snai2" "Mmus\Snai1, Mmus\Snai3, Mmus\Snai2, Mmus\Scrt1, Mmus\Scrt2, Mmus\Zfp580" "Hsap\SNAI1, Hsap\SNAI2, Hsap\ZNF580, Hsap\SNAI3, Hsap\SCRT2, Hsap\SCRT1" " embryonic stage , embryonic stage | 5.5 hr , embryonic stage | 5-5.5 hr , embryonic stage | >6.5 hr , embryonic stage | 4-12 hr , larval stage | third instar , pupal stage " " ganglion mother cell

, stage 1 neuroblast | row 1..3

, ectoderm | restricted

, stage 1 neuroblast

, eye-antennal disc | restricted

, ventral thoracic disc | restricted

, sensory mother cell

, dorsal mesothoracic disc | restricted

, wing | restricted

" "visible,recessive,uncoordinated,behavior defective,lethal - all die before end of pupal stage,some die during pupal stage" "neuron,photoreceptor cell,macrochaeta,microchaeta,posterior crossvein,anterior crossvein,eye,wing,eye photoreceptor cell,pigment cell" FBgn0003053 peb pebbled http://flybase.org/reports/FBgn0003053 "FBgn0001209, FBgn0019888" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000579295" "amnioserosa maintenance ; GO:0046665 | traceable author statement maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from genetic interaction with tor germ-band shortening ; GO:0007390 | traceable author statement photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement negative regulation of protein localization to plasma membrane ; GO:1903077 | inferred from mutant phenotype regulation of tube architecture, open tracheal system ; GO:0035152 | traceable author statement negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with bsk inferred from genetic interaction with dpp dorsal closure ; GO:0007391 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement positive regulation of epithelial cell-cell adhesion involved in epithelium migration ; GO:1903683 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype positive regulation of homophilic cell adhesion ; GO:1903387 | inferred from mutant phenotype head involution ; GO:0008258 | non-traceable author statement dorsal closure, leading edge cell fate determination ; GO:0007393 | non-traceable author statement positive regulation of border follicle cell migration ; GO:1903688 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from expression pattern amnioserosa maintenance ; GO:0046665 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with dally dorsal closure ; GO:0007391 | traceable author statement negative regulation of STAT protein import into nucleus ; GO:2000365 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "hnt, Hnt, Hind, HNT, CG12212, EP55, hnd, PEB, anon-4Cg, EG:66A1.1, peb, Peb, Hin" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG12212 11-Aug-17 DroID_v2017_08 "Drer\rreb1a, Drer\rreb1b, Drer\sall2, Drer\znf536, Drer\znf516, Drer\znf219, Drer\zbtb48, Drer\znf217" - Cele\sem-4 "Xtro\zbtb48, Xtro\rreb1" "Mmus\Zfp516, Mmus\Zfp217, Mmus\Rreb1, Mmus\Sall2, Mmus\Zfp536, Mmus\Zbtb48, Mmus\Zfp219, Mmus\Zfp821" "Hsap\ZNF217, Hsap\ZNF821, Hsap\ZNF536, Hsap\RREB1, Hsap\ZBTB48, Hsap\ZNF516, Hsap\ZNF219, Hsap\SALL2" embryonic stage | stage >=5 amnioserosa | presumptive

" embryonic stage | >=stage 11 , embryonic stage | stage >=11 , embryonic stage | stage >=6 , embryonic stage | stage 12 , embryonic stage | stage >=8 " " embryonic/larval tracheal system

, embryonic peripheral nervous system

, amnioserosa | presumptive

, CNS glial cell

, anterior midgut proper primordium

, PNS glial cell

" "partially lethal - majority die,visible,lethal,lethal - all die before end of embryonic stage,partially,recessive,some die during embryonic stage,wild-type,somatic clone,viable,heat sensitive,planar polarity defective" "eye,embryonic/first instar larval cuticle,dorsal,extended germ band embryo,ommatidial precursor cluster,somatic clone,amnioserosa,dorsal closure embryo,cephalopharyngeal skeleton,five-cell ommatidial precursor cluster,eye photoreceptor cell,embryonic/larval dorsal trunk,embryonic/larval tracheal system,posterior,taenidium,taenidial fold,germ band,embryonic head,dorsal bridge,vertical bridge,cuticle,filzkorper,heat sensitive,ommatidium,interommatidial bristle,rhabdomere,salivary gland,anterior" FBgn0259984 kuz kuzbanian http://flybase.org/reports/FBgn0259984 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from direct assay metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity with MGI:MGI:109548 inferred from genetic interaction with N Notch signaling pathway ; GO:0007219 | inferred from electronic annotation with InterPro:IPR027053 membrane protein ectodomain proteolysis ; GO:0006509 | inferred from direct assay oogenesis ; GO:0048477 | inferred from mutant phenotype muscle tissue development ; GO:0060537 | inferred from mutant phenotype membrane protein ectodomain proteolysis ; GO:0006509 | inferred from sequence or structural similarity with HGNC:195 regulation of Roundabout signaling pathway ; GO:0035386 | inferred from genetic interaction with robo1 central nervous system development ; GO:0007417 | traceable author statement Notch signaling pathway ; GO:0007219 | traceable author statement neuroblast fate determination ; GO:0007400 | inferred from direct assay border follicle cell migration ; GO:0007298 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype pericardial nephrocyte differentiation ; GO:0061320 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from genetic interaction with H inferred from genetic interaction with Ser inferred from genetic interaction with N cardiocyte differentiation ; GO:0035051 | inferred from mutant phenotype lymph gland development ; GO:0048542 | inferred from mutant phenotype regulation of axon extension ; GO:0030516 | traceable author statement skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype heart morphogenesis ; GO:0003007 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:195 perivitelline space ; GO:0098595 | inferred from direct assay "Kuz, kuz, GS11410, 11410, CG7147, CT22079, BG:DS07660.3, l(2)34Da, l(2)k01403, l(2)br38, l34Da, 34Da, br38, l(2)c00136, l(2)03782, ADAM10, soy nut, KUZ" "IPR001590:Peptidase M12B, ADAM/reprolysin, IPR001762:Disintegrin domain, IPR034025:ADAM10/ADAM17 catalytic domain, IPR024079:Metallopeptidase, catalytic domain, IPR002870:Peptidase M12B, propeptide, IPR027053:Disintegrin and metalloproteinase domain-containing protein 10" CG7147 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-396h14.1, Drer\adam17b, Drer\adam17a, Drer\adam10a, Drer\adam10b" - Cele\sup-17 "Xtro\adam10, Xtro\adam17" "Mmus\Adam17, Mmus\Adam10" "Hsap\ADAM17, Hsap\ADAM10" " larval stage | third instar , embryonic stage | late , embryonic stage " " ommatidial precursor cluster

, embryonic central nervous system

, epidermis

, ventral nerve cord

, morphogenetic furrow

, imaginal disc | ubiquitous

,

ubiquitous , eye-antennal disc

" FBgn0013272 Gp150 Gp150 http://flybase.org/reports/FBgn0013272 "FBgn0022992, FBgn0025238, FBgn0027193" protein_coding_gene - compound eye development ; GO:0048749 | inferred from mutant phenotype transmembrane receptor protein tyrosine phosphatase signaling pathway ; GO:0007185 | inferred from direct assay inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "gp150, GP150, CT18251, p150, anon-EST:fe2A1, CG5820, l(2)52A, Gp150" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG5820 11-Aug-17 DroID_v2017_08 Drer\tlr8b - "Cele\lron-11, Cele\let-4, Cele\lron-14" - Mmus\Tlr3 Hsap\TLR3 " embryonic stage , embryonic stage | stage 3-12 , embryonic stage | stage 10-12 " "

ubiquitous ,

segmentally repeated , ventral midline

" larval stage eye disc

"lethal,recessive,partially lethal - majority die,female sterile,visible,male semi-sterile,lethal - all die before end of pupal stage,some die during pupal stage,body color defective,behavior defective" "ommatidium,wing margin bristle,ectopic,wing vein L3,eye,eye photoreceptor cell,somatic clone,photoreceptor cell R8,cell autonomous,anterior scutellar bristle,photoreceptor cell R1,photoreceptor cell R6,macrochaeta,ocellar bristle,mesothoracic tergum & microchaeta,wing margin,mesothoracic tergum,chaeta,supernumerary,trichogen cell" FBgn0021742 C901 C901 http://flybase.org/reports/FBgn0021742 FBgn0014895 protein_coding_gene - cell communication ; GO:0007154 | inferred from electronic annotation with InterPro:IPR001774 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001774 "CT4052, c901, 10, cDNA 901, anon-10Ab, CG1567, C901" "IPR000742:EGF-like domain, IPR001774:Delta/Serrate/lag-2 (DSL) protein, IPR013032:EGF-like, conserved site, IPR002049:Laminin EGF domain" CG1567 11-Aug-17 DroID_v2017_08 - - "Cele\glp-1, Cele\nid-1" - Mmus\Megf6 "Hsap\MEGF6, Hsap\DLK2, Hsap\DLK1" " larval stage | second instar , larval stage | first instar , embryonic stage | 9-15hr , pupal stage , embryonic stage | 8-12hr " "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0016762 angel angel http://flybase.org/reports/FBgn0016762 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12273, angel, Angel" IPR005135:Endonuclease/exonuclease/phosphatase CG12273 11-Aug-17 DroID_v2017_08 "Drer\angel2, Drer\angel1" Scer\CCR4 Cele\angl-1 "Xtro\angel1, Xtro\angel2, Xtro\noct" "Mmus\Noct, Mmus\Angel2, Mmus\Angel1" "Hsap\NOCT, Hsap\ANGEL2, Hsap\ANGEL1" " embryonic stage , embryonic stage -- adult stage "

ubiquitous viable FBgn0261714 Cpn Calphotin http://flybase.org/reports/FBgn0261714 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from direct assay rhabdomere development ; GO:0042052 | inferred from mutant phenotype sequestering of calcium ion ; GO:0051208 | inferred from direct assay inferred from mutant phenotype sequestering of calcium ion ; GO:0051208 | inferred by curator from GO:0005509 cell body ; GO:0044297 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay mitochondrion ; GO:0005739 | NOT inferred from direct assay rhabdomere ; GO:0016028 | NOT inferred from direct assay rough endoplasmic reticulum ; GO:0005791 | NOT inferred from direct assay nucleus ; GO:0005634 | NOT inferred from direct assay "Cpn, cpn, Ag 72H5, cap, CG4795, Ag72H5, 77H5, Mab77H5" - CG4795 11-Aug-17 DroID_v2017_08 Drer\si:ch73-366l1.5 - - - - "Hsap\MUC1, Hsap\SNAP91" adult stage " head

, ocellus

, photoreceptor cell R1--8

, adult head

{ - cli* } " " adult stage , larval stage,adult stage , larval stage && adult stage , larval stage | third instar " " ocellus

, photoreceptor cell R1--8

, optic lobe

, photoreceptor cell

{ 0 gl* } , eye-antennal disc

" FBgn0005603 yemG3.4 yema gene 3.4 http://flybase.org/reports/FBgn0005603 FBgn0004042 gene - - - "yG3.4, yT3.4, yemG3.4" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 1-5 , adult stage && oogenesis stage , embryonic stage | pre-blastoderm " " organism

, ovary

" FBgn0060296 pain painless http://flybase.org/reports/FBgn0060296 protein_coding_gene calcium activated cation channel activity ; GO:0005227 | inferred from direct assay calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity calcium channel activity ; GO:0005262 | inferred from direct assay ion channel activity ; GO:0005216 | traceable author statement calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity thermotaxis ; GO:0043052 | NOT inferred from mutant phenotype negative gravitaxis ; GO:0048060 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype detection of temperature stimulus involved in thermoception ; GO:0050960 | inferred from mutant phenotype detection of temperature stimulus involved in thermoception ; GO:0050960 | inferred from direct assay regulation of heart contraction ; GO:0008016 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception of pain ; GO:0050966 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception ; GO:0050974 | traceable author statement response to heat ; GO:0009408 | traceable author statement detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype feeding behavior ; GO:0007631 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype sensory perception of pain ; GO:0019233 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | non-traceable author statement larval turning behavior ; GO:0035179 | inferred from mutant phenotype behavioral response to pain ; GO:0048266 | inferred from mutant phenotype copulation ; GO:0007620 | inferred from mutant phenotype calcium ion transmembrane transport ; GO:0070588 | inferred from direct assay calcium channel complex ; GO:0034704 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement "EP2251, CT31987, CG15860, pain, Pain" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR005821:Ion transport domain" CG15860 11-Aug-17 DroID_v2017_08 "Drer\trpa1a, Drer\trpa1b" - "Cele\trpa-2, Cele\trpa-1" Xtro\trpa1 Mmus\Trpa1 Hsap\TRPA1 " embryonic stage , embryonic stage | stage 17 ," " antenno-maxillary complex

, chordotonal organ

, multidendritic dendrite

, multidendritic neuron

, gonad

, embryonic heart

, central nervous system

restricted " " embryonic stage | stage 17 , larval stage | third instar " " chordotonal organ

, multidendritic dendrite

" "taste perception defective,chemosensitive behavior defective,courtship behavior defective,gravitaxis defective,neurophysiology defective,smell perception defective,sensory perception defective,pain response defective,recessive,heat stress response defective,thermotaxis behavior defective,touch sensitivity defective,lethal,partially,semidominant,visible,wild-type,viable" "Johnston organ neuron,embryonic/larval heart,scutellar bristle,ectopic" DRSC28351 K 1.132512419 -0.125975082 0.528416464 -0.301034969 0.026232244 2.576307954 FBgn0052380 SMSr SMSr http://flybase.org/reports/FBgn0052380 protein_coding_gene ceramide cholinephosphotransferase activity ; GO:0047493 | inferred from direct assay sphingomyelin synthase activity ; GO:0033188 | inferred from direct assay sphingomyelin biosynthetic process ; GO:0006686 | non-traceable author statement Golgi organization ; GO:0007030 | inferred from mutant phenotype ceramide biosynthetic process ; GO:0046513 | inferred from direct assay regulation of cell diameter ; GO:0060305 | inferred from mutant phenotype regulation of ceramide biosynthetic process ; GO:2000303 | inferred from direct assay integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000480004 integral component of membrane ; GO:0016021 | non-traceable author statement integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000480004 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from direct assay "CG8576, Css3beta, CG8572, CG32380, SMSr, dmSMSr, dSMSr" "IPR025749:Sphingomyelin synthase-like domain, IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG32380 11-Aug-17 DroID_v2017_08 "Drer\sgms2, Drer\zgc:162183, Drer\zgc:100911, Drer\zgc:91976, Drer\sgms1, Drer\zgc:175139, Drer\lrrc6" - "Cele\W07E6.3, Cele\sms-2, Cele\sms-3, Cele\F53B1.2, Cele\sms-1" "Xtro\sgms1, Xtro\samd8, Xtro\lrrc6, Xtro\sgms2" "Mmus\Sgms1, Mmus\Sgms2, Mmus\Lrrc6, Mmus\Samd8" "Hsap\SAMD8, Hsap\SGMS2, Hsap\SGMS1" "viable,fertile" DRSC10999 I -0.644999539 -1.963394644 -0.122716862 -0.391140968 -1.256008827 0.842599466 FBgn0003204 ras raspberry http://flybase.org/reports/FBgn0003204 "FBgn0026670, FBgn0026696, FBgn0028270, FBgn0028295, FBgn0028297, FBgn0028302, FBgn0028318, FBgn0028340, FBgn0028363, FBgn0029044, FBgn0030231, FBgn0030232, FBgn0040205" protein_coding_gene IMP dehydrogenase activity ; GO:0003938 | inferred from sequence or structural similarity with MGI:MGI:96567 IMP dehydrogenase activity ; GO:0003938 | inferred from biological aspect of ancestor with PANTHER:PTN000226903 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001093, InterPro:IPR005990, InterPro:IPR015875 oogenesis ; GO:0048477 | traceable author statement purine nucleotide biosynthetic process ; GO:0006164 | inferred from sequence or structural similarity with MGI:MGI:96567 axon guidance ; GO:0007411 | inferred from mutant phenotype GTP biosynthetic process ; GO:0006183 | inferred from biological aspect of ancestor with PANTHER:PTN000226903 phagocytosis ; GO:0006909 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000226902 "IMPdH, CG11485, LD06825, LD02673, EP(X)1093, IMPDH, raspberry/impd, l(1)G0002, l(1)G0482, l(1)G0098, l(1)G0351, l(1)G0388, l(1)G0391, l(1)G0436, l(1)G0238, l(1)G0056, l(1)G0127, l(1)G0380, ras-l, l(1)9Eb, CG1799, ras, raspberry, Ras" "IPR015875:IMP dehydrogenase / GMP reductase, conserved site, IPR000644:CBS domain, IPR001093:IMP dehydrogenase/GMP reductase, IPR005990:Inosine-5'-monophosphate dehydrogenase, IPR013785:Aldolase-type TIM barrel" CG1799 11-Aug-17 DroID_v2017_08 "Drer\gmpr2, Drer\impdh1b, Drer\impdh2, Drer\gmpr, Drer\impdh1a" "Scer\IMD2, Scer\IMD4, Scer\IMD3" "Cele\T22D1.3, Cele\F32D1.5" "Xtro\impdh1, Xtro\gmpr2, Xtro\impdh2, Xtro\gmpr" "Mmus\Impdh2, Mmus\Gmpr, Mmus\Impdh1, Mmus\Gmpr2" "Hsap\IMPDH1, Hsap\IMPDH2, Hsap\GMPR2, Hsap\GMPR" " spermatogenesis && adult stage , embryonic stage -- adult stage , oogenesis stage && adult stage | female " " testis

, ovary

" "viable,fertile,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,wild-type,lethal - all die before end of pupal stage,some die during pupal stage,female,partially lethal - majority die,visible,neuroanatomy defective,eye color defective,developmental rate defective,female sterile,partially,heat sensitive" "macrochaeta,embryonic/larval hemocyte | third instar larval stage,photoreceptor cell & axon,pigment cell,ovariole,germline clone,egg,Malpighian tubule,heat sensitive,testis" DRSC27137 IEK 1.79588902 0.12656012 2.024175332 -0.919064105 -1.11927727 -1.53594252 FBgn0031492 CG3542 - http://flybase.org/reports/FBgn0031492 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000221451 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000221451 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000001495 inferred from sequence or structural similarity with protein_id:AAD39463" U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity with SGD:S000001495 inferred from sequence or structural similarity with protein_id:AAD39463 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000221451 U1 snRNP ; GO:0005685 | inferred from biological aspect of ancestor with PANTHER:PTN000221451 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG3542, prp40" "IPR001202:WW domain, IPR002713:FF domain" CG3542 11-Aug-17 DroID_v2017_08 "Drer\prpf40a, Drer\waca" "Scer\URN1, Scer\PRP40" "Cele\tcer-1, Cele\ZK1098.1" "Xtro\prpf40b, Xtro\wac, Xtro\prpf40a" "Mmus\Prpf40b, Mmus\Prpf40a" "Hsap\PRPF40B, Hsap\PRPF40A" "lethal,recessive,viable,visible" "trichogen cell,mesothoracic tergum" DRSC00612 E -0.159520528 -0.6607872 -0.178901226 -1.782933201 -0.729295803 0.075788606 FBgn0000055 Adh Alcohol dehydrogenase http://flybase.org/reports/FBgn0000055 "FBgn0016704, FBgn0052954" protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Adh alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from direct assay alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from mutant phenotype acetaldehyde dehydrogenase (acetylating) activity ; GO:0008774 | inferred from direct assay alcohol catabolic process ; GO:0046164 | inferred from mutant phenotype ethanol metabolic process ; GO:0006067 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype alcohol metabolic process ; GO:0006066 | inferred from direct assay ethanol oxidation ; GO:0006069 | inferred from direct assay acetaldehyde metabolic process ; GO:0006117 | inferred from direct assay acetaldehyde metabolic process ; GO:0006117 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Adh "ADH, CG3481, T16, adh, BG:DS01486.8, Dreg-1, dADH, DmADH, CG32954, Reg-1, Adh, DM-ADH, Adh3" "IPR002424:Alcohol dehydrogenase, insect-type, IPR002425:Alcohol dehydrogenase, Drosophila-type, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site, IPR002347:Short-chain dehydrogenase/reductase SDR" CG3481 11-Aug-17 DroID_v2017_08 "Drer\hpgd, Drer\zgc:56585" "Scer\SPS19, Scer\YMR226C" "Cele\T01G6.10, Cele\C01G12.5, Cele\W03F9.9, Cele\T01G6.1, Cele\C06B8.3" Xtro\hpgd Mmus\Hpgd Hsap\HPGD " adult stage , larval stage , larval stage | third instar , adult stage && oogenesis stage , embryonic stage | stage 17 , embryonic stage | early , embryonic stage | stage 14-16 , embryonic stage | stage 16 , embryonic stage | stage 14-15 " " cardial valve

, pharyngeal muscle

, embryonic/larval salivary gland

, gastric caecum

, nurse cell

, imaginal disc

, embryonic/larval midgut

, embryonic/larval fat body

, posterior embryonic/larval midgut

, larval brain

, mid embryonic/larval midgut

, oocyte

, anterior embryonic/larval midgut

, adult fat body

, adult brain

" " adult stage , adult stage && oogenesis stage , larval stage " " Malpighian tubule

, ovary

, cardial valve

, nurse cell

, midgut

, cystocyte

, adult fat body

, oocyte

, embryonic/larval digestive system

, embryonic/larval fat body

, gastric caecum

, male reproductive system

" "chemical sensitive,electrophoretic variant,fast,wild-type,slow,locomotor behavior defective,drug conditional,chemical resistant" FBgn0036288 CG10660 - http://flybase.org/reports/FBgn0036288 protein_coding_gene - - - CG10660 IPR000008:C2 domain CG10660 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC09769 E 0.210534236 -0.811158656 2.675545125 -2.589505753 0.848558629 0.854153372 FBgn0035533 Cip4 Cdc42-interacting protein 4 http://flybase.org/reports/FBgn0035533 protein_coding_gene "phospholipid binding ; GO:0005543 | inferred from sequence model GTPase activating protein binding ; GO:0032794 | inferred from physical interaction with RhoGAP92B lipid binding ; GO:0008289 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with dia, SCAR" endocytosis ; GO:0006897 | inferred from electronic annotation with InterPro:IPR028532 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR011072 imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern regulation of adherens junction organization ; GO:1903391 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype membrane tubulation ; GO:0097320 | inferred from direct assay negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype plasma membrane organization ; GO:0007009 | inferred from mutant phenotype cellular protein localization ; GO:0034613 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from direct assay negative regulation of actin nucleation ; GO:0051126 | inferred from direct assay membrane tubulation ; GO:0097320 | inferred from mutant phenotype negative regulation of actin filament polymerization ; GO:0030837 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay vesicle membrane ; GO:0012506 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay "CG15015, DCIP4, CG11341, Cip4, cip4, dCIP4, dcip4" "IPR001060:FCH domain, IPR001452:SH3 domain, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR028532:Formin-binding protein 1, IPR011072:HR1 rho-binding repeat, IPR031160:F-BAR domain" CG15015 11-Aug-17 DroID_v2017_08 "Drer\sh3d19, Drer\pacsin1a, Drer\LOC562049, Drer\itsn2b, Drer\fnbp1a, Drer\fnbp1l, Drer\itsn1, Drer\trip10a, Drer\pacsin3, Drer\pacsin1b, Drer\itsn2a, Drer\trip10b" "Scer\LSB1, Scer\LSB3, Scer\YSC84, Scer\BZZ1" "Cele\toca-1, Cele\itsn-1, Cele\B0303.7, Cele\sdpn-1, Cele\toca-2" "Xtro\fnbp1, Xtro\fnbp1l" "Mmus\Itsn1, Mmus\Pacsin1, Mmus\Trip10, Mmus\Fnbp1, Mmus\Itsn2, Mmus\Pacsin2, Mmus\Sh3d19, Mmus\Pacsin3, Mmus\Fnbp1l, Mmus\Sh3yl1" "Hsap\SH3YL1, Hsap\FCHSD1, Hsap\PACSIN2, Hsap\ITSN2, Hsap\GRAP2, Hsap\SH3D19, Hsap\PACSIN3, Hsap\TRIP10, Hsap\FNBP1, Hsap\FNBP1L, Hsap\PACSIN1, Hsap\ITSN1" "visible,viable,lethal,fertile,partially lethal - majority die,neuroanatomy defective" "wing hair,supernumerary,wing,NMJ bouton,neuromuscular junction,neuromuscular junctionED4342),neuromuscular junctionC57,bouton" DRSC21740 I 1.174162123 -1.654727835 -0.134553747 1.295642373 0.557609548 -0.067657873 FBgn0010497 dmGlut Dietary and metabolic glutamate transporter http://flybase.org/reports/FBgn0010497 "FBgn0032396, FBgn0061550" protein_coding_gene sodium-dependent phosphate transmembrane transporter activity ; GO:0015321 | inferred from mutant phenotype high-affinity glutamate transmembrane transporter activity ; GO:0005314 | inferred from direct assay sodium:inorganic phosphate symporter activity ; GO:0015319 | NOT inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 L-glutamate import ; GO:0051938 | inferred from direct assay sodium-dependent phosphate transport ; GO:0044341 | NOT inferred from direct assay sodium-dependent phosphate transport ; GO:0044341 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype inferred from genetic interaction with SelD glutamine metabolic process ; GO:0006541 | inferred from mutant phenotype inferred from genetic interaction with SelD plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "CG5304, anon-WO0118547.88, MFS13, l(2)01810, dmGlut, DMGLUT, lethal(2)01810, I(2)01810" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG5304 11-Aug-17 DroID_v2017_08 "Drer\slc17a7a, Drer\ppt1, Drer\slc17a7b, Drer\slc17a5, Drer\slc17a8, Drer\slc17a9a, Drer\slc17a6b, Drer\slc17a6a, Drer\si:ch1073-513e17.1" "Scer\DAL5, Scer\THI73, Scer\TNA1, Scer\VHT1, Scer\FEN2, Scer\YIL166C" "Cele\vglu-2, Cele\slc-17.6, Cele\slc-17.1, Cele\slc-17.7, Cele\slc-17.5, Cele\slc-17.2, Cele\vglu-3, Cele\eat-4" Xtro\slc17a7 "Mmus\Slc17a8, Mmus\Slc17a3, Mmus\Slc17a6, Mmus\Slc17a7, Mmus\Slc17a4, Mmus\Slc17a5, Mmus\Slc17a1, Mmus\Slc17a2" "Hsap\SLC17A4, Hsap\SLC17A1, Hsap\SLC17A5, Hsap\SLC17A8, Hsap\SLC17A6, Hsap\SLC17A7, Hsap\SLC17A2, Hsap\SLC17A3" "viable,partially lethal - majority die,lethal,recessive" DRSC02835 E -0.454567138 0.249802624 -0.445641978 1.627740877 0.153558934 -0.121219183 FBgn0050491 CG30491 - http://flybase.org/reports/FBgn0050491 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - - "CG2074, CG17986, CG30491" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG30491 11-Aug-17 DroID_v2017_08 "Drer\zgc:112332, Drer\rdh12, Drer\rdh12l, Drer\si:ch211-107o10.3, Drer\dhrsx, Drer\si:dkey-23o4.6, Drer\si:ch211-165b10.3, Drer\zgc:64106, Drer\rdh14a, Drer\ascc1, Drer\dhrs13l1, Drer\dhrs13a.2, Drer\dhrs12, Drer\cbr1l, Drer\zgc:153441, Drer\dhrs13a.1, Drer\dhrs13a.3, Drer\flj13639, Drer\rdh14b, Drer\cbr1, Drer\si:dkey-73n8.3, Drer\si:dkey-174n20.1, Drer\si:dkey-94e7.2" "Scer\YKL107W, Scer\GPI11, Scer\YNL181W, Scer\ENV9, Scer\ERG27" "Cele\DC2.5, Cele\dhs-22, Cele\E04F6.15, Cele\C27D8.4" "Xtro\dhrs13, Xtro\ascc1, Xtro\dhrs12, Xtro\rdh14, Xtro\rdh11, Xtro\rdh13, Xtro\dhrsx" "Mmus\Rdh12, Mmus\Rdh11, Mmus\Dhrs13, Mmus\Ascc1, Mmus\Rdh13, Mmus\Dhrsx, Mmus\Cbr1, Mmus\1700003E16Rik, Mmus\Wwox, Mmus\Hsd17b7, Mmus\Rdh14, Mmus\Cbr3" "Hsap\DHRS12, Hsap\OSTC, Hsap\RDH11, Hsap\HSD17B7, Hsap\DHRSX, Hsap\RDH14, Hsap\CBR3, Hsap\CBR1, Hsap\RDH13, Hsap\DHRS13, Hsap\RDH12, Hsap\C2orf81" viable DRSC21472 IE 1.628864705 0.285729464 2.5400331 1.314574665 1.06633405 -0.185142479 FBgn0052581 CG32581 - http://flybase.org/reports/FBgn0052581 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ubiquitin-like protein conjugating enzyme binding ; GO:0044390 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10068 ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:10068 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 Derlin-1 retrotranslocation complex ; GO:0036513 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 CG32581 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG32581 11-Aug-17 DroID_v2017_08 "Drer\rnf5, Drer\rnf185, Drer\rnf20, Drer\pex10, Drer\rnf4, Drer\si:ch211-247l8.8" "Scer\THI21, Scer\BRE1, Scer\PEX10, Scer\SLX8" "Cele\Y47G6A.31, Cele\rnf-5, Cele\rfp-1" "Xtro\rnf5, Xtro\rnf185" "Mmus\Rnf40, Mmus\Nr2c1, Mmus\Trim39, Mmus\Rnf185, Mmus\Rnf20, Mmus\Rnf4, Mmus\Pex10, Mmus\Rnf5" "Hsap\RNF4, Hsap\TRIM39, Hsap\RNF20, Hsap\RNF185, Hsap\RNF5, Hsap\PEX10, Hsap\RNF40" DRSC20136 K 0.673840783 0.280899511 -0.05639009 0.051514521 -0.19695688 1.84177095 FBgn0011676 Nos Nitric oxide synthase http://flybase.org/reports/FBgn0011676 - protein_coding_gene "NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR012144 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012144 FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR008254, InterPro:IPR012144 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR012144 calmodulin binding ; GO:0005516 | inferred from electronic annotation with InterPro:IPR012144 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR012144 calmodulin binding ; GO:0005516 | non-traceable author statement heme binding ; GO:0020037 | non-traceable author statement nitric-oxide synthase activity ; GO:0004517 | inferred from sequence or structural similarity with MGI:MGI:97361 inferred from sequence or structural similarity with RGDID:3184 inferred from direct assay inferred from mutant phenotype nitric-oxide synthase activity ; GO:0004517 | traceable author statement NADPH-hemoprotein reductase activity ; GO:0003958 | inferred from biological aspect of ancestor with PANTHER:PTN000453822 nitric-oxide synthase activity ; GO:0004517 | inferred from sequence or structural similarity with HGNC:7873" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR003097, InterPro:IPR004030, InterPro:IPR017927, InterPro:IPR017938, InterPro:IPR023173 nitric oxide biosynthetic process ; GO:0006809 | inferred from electronic annotation with InterPro:IPR004030, InterPro:IPR012144 regulation of organ growth ; GO:0046620 | traceable author statement nitric oxide mediated signal transduction ; GO:0007263 | inferred from biological aspect of ancestor with PANTHER:PTN001066032 imaginal disc development ; GO:0007444 | traceable author statement positive regulation of guanylate cyclase activity ; GO:0031284 | inferred from biological aspect of ancestor with PANTHER:PTN001066032 negative regulation of DNA replication ; GO:0008156 | traceable author statement nitric oxide biosynthetic process ; GO:0006809 | traceable author statement negative regulation of cell proliferation ; GO:0008285 | traceable author statement synapse assembly ; GO:0007416 | traceable author statement nervous system development ; GO:0007399 | inferred from mutant phenotype regulation of heart rate ; GO:0002027 | inferred from mutant phenotype" peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:7873 "NOS, dNOS, DNOS, DNOS1, CG6713, Nos, drNOSoxy, dNos, nNOS, nos" "IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR001709:Flavoprotein pyridine nucleotide cytochrome reductase, IPR003097:FAD-binding, type 1, IPR004030:Nitric oxide synthase, N-terminal, IPR008254:Flavodoxin/nitric oxide synthase, IPR012144:Nitric-oxide synthase, eukaryote, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel, IPR029039:Flavoprotein-like domain, IPR001094:Flavodoxin-like" CG6713 11-Aug-17 DroID_v2017_08 "Drer\pora, Drer\nos2b, Drer\porb, Drer\mtrr, Drer\nos2a, Drer\nos1" "Scer\MET10, Scer\NCP1" "Cele\mei-2, Cele\F47G4.4" "Xtro\nos3, Xtro\por, Xtro\mtrr, Xtro\nos2, Xtro\nos1" "Mmus\Mtrr, Mmus\Nos3, Mmus\Nos2, Mmus\Nos1, Mmus\Por" "Hsap\NOS2, Hsap\NOS3, Hsap\POR, Hsap\MTRR, Hsap\NOS1" adult stage adult head

" larval stage | third instar , larval stage | third instar && P , larval stage | third instar--P , larval stage | third instar && P " " larval brain

, dorsal metathoracic disc

, ventral thoracic disc

, genital disc

, histoblast

" "developmental rate defective,large body,eclosion defective,increased cell size,small body,lethal - all die before end of larval stage,some die during larval stage,chemical resistant,dominant,viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "prothoracic gland,embryonic/larval fat body,vesiclephm.PO,eye & cell cycle,secondary pigment cell,tertiary pigment cell,interommatidial bristle,cell cycle,mesothoracic tergum" FBgn0004607 zfh2 Zn finger homeodomain 2 http://flybase.org/reports/FBgn0004607 - protein_coding_gene RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 wing disc development ; GO:0035220 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from expression pattern imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "zfh2, Zfh-2, zfh-2, Zfh2, ZFH-2, CG1449, ZFH2" "IPR017970:Homeobox, conserved site, IPR013087:Zinc finger C2H2-type, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1449 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-386h18.1, Drer\zfhx2, Drer\zfhx4" - Cele\zfh-2 "Xtro\zfhx4, Xtro\zfhx3, Xtro\zfhx2" "Mmus\Zfhx2, Mmus\Zfhx4, Mmus\Zfhx3" "Hsap\ZFHX4, Hsap\ZFHX3, Hsap\ZFHX2" " embryonic stage | stage 13-15 , embryonic stage | stage 15 " " embryonic central nervous system

, embryonic/larval hindgut

" " embryonic stage , embryonic stage | stage 15-17 , embryonic stage | stage 13-15 , larval stage , embryonic stage | stage 15 " " embryonic central nervous system | lateral

, EW3 neuron

, embryonic central nervous system

, EW2 neuron

, abdominal 3--6 neuroblast ventro-lateral cluster neuron

, abdominal 3--7 neuroblast dorso-lateral cluster

, embryonic/larval hindgut

, larval central nervous system

" "viable,poor,visible,partially lethal - majority die,some die during pupal stage,lethal,recessive,lethal - all die before end of pupal stage" "wing,proximal,alula,medial costal vein,wing vein L1,wing disc,sclerite,wing hinge,eye,chaeta,ectopic" FBgn0039914 mav maverick http://flybase.org/reports/FBgn0039914 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR001111, InterPro:IPR001839, InterPro:IPR017948 cytokine activity ; GO:0005125 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 transforming growth factor beta receptor binding ; GO:0005160 | inferred from biological aspect of ancestor with PANTHER:PTN000218063" cell development ; GO:0048468 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 BMP signaling pathway ; GO:0030509 | inferred from biological aspect of ancestor with PANTHER:PTN000218210 positive regulation of pathway-restricted SMAD protein phosphorylation ; GO:0010862 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from mutant phenotype regulation of MAPK cascade ; GO:0043408 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 SMAD protein signal transduction ; GO:0060395 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 synaptic cleft ; GO:0043083 | inferred from direct assay extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 "Mav, TGF-b, CG1901, mav, MAV" "IPR001111:TGF-beta, propeptide, IPR001839:Transforming growth factor-beta, C-terminal, IPR015615:Transforming growth factor-beta-related, IPR017948:Transforming growth factor beta, conserved site, IPR029034:Cystine-knot cytokine" CG1901 11-Aug-17 DroID_v2017_08 "Drer\bmp7b, Drer\lft2, Drer\admp, Drer\inha, Drer\gdf5, Drer\inhbaa, Drer\inhbab, Drer\bmp7a, Drer\tgfb2, Drer\inhbb, Drer\bmp8a, Drer\bmp10, Drer\lft1, Drer\gdf10b, Drer\gdf6a, Drer\bmp6, Drer\bmp2a, Drer\gdf9, Drer\tgfb2l, Drer\ndr1, Drer\bmp15, Drer\tgfb1b, Drer\gdf10a, Drer\gdf2, Drer\gdf3, Drer\amh, Drer\spaw, Drer\bmp3, Drer\mstna, Drer\mstnb, Drer\ndr2, Drer\bmp2b, Drer\gdf11, Drer\gdf7, Drer\LOC100329520, Drer\bmp4, Drer\gdf6b, Drer\bmp10l, Drer\tgfb1a, Drer\tgfb3" - "Cele\tig-2, Cele\daf-7, Cele\dbl-1, Cele\unc-129" "Xtro\gdf1, Xtro\gdf3, Xtro\nodal, Xtro\admp, Xtro\gdf7, Xtro\nodal, Xtro\gdf11.1, Xtro\tgfb1, Xtro\bmp15, Xtro\gdf5, Xtro\bmp6, Xtro\inha, Xtro\bmp7.2, Xtro\bmp7.1, Xtro\bmp4, Xtro\lefty, Xtro\bmp10, Xtro\tgfb2, Xtro\nodal5, Xtro\inhbc.1, Xtro\bmp5, Xtro\gdf2, Xtro\mstn.1, Xtro\gdf10, Xtro\bmp3, Xtro\nodal1, Xtro\gdf9, Xtro\bmp2, Xtro\nodal6, Xtro\bmp8" "Mmus\Lefty1, Mmus\Lefty2, Mmus\Gdf7, Mmus\Tgfb1, Mmus\Inha, Mmus\Inhbb, Mmus\Nodal, Mmus\Gdf10, Mmus\Gdf6, Mmus\Bmp5, Mmus\Tgfb3, Mmus\Bmp6, Mmus\Inhbc, Mmus\Gdf2, Mmus\Bmp8b, Mmus\Bmp2, Mmus\Gdf11, Mmus\Bmp3, Mmus\Inhba, Mmus\Inhbe, Mmus\Bmp4, Mmus\Gdf1, Mmus\Gdf3, Mmus\Bmp15, Mmus\Gdf5, Mmus\Amh, Mmus\Bmp7, Mmus\Tgfb2, Mmus\Gdf15, Mmus\Mstn, Mmus\Bmp10, Mmus\Gdf9, Mmus\Bmp8a" "Hsap\INHBE, Hsap\TGFB2, Hsap\TGFB1, Hsap\BMP6, Hsap\GDF7, Hsap\BMP3, Hsap\BMP2, Hsap\BMP15, Hsap\BMP8A, Hsap\NODAL, Hsap\LEFTY2, Hsap\MSTN, Hsap\BMP4, Hsap\INHBA, Hsap\AMH, Hsap\BMP7, Hsap\BMP8B, Hsap\INHBB, Hsap\BMP10, Hsap\GDF6, Hsap\LEFTY1, Hsap\GDF1, Hsap\BMP5, Hsap\GDF5, Hsap\GDF9, Hsap\GDF15, Hsap\INHA, Hsap\GDF10, Hsap\GDF11, Hsap\TGFB3, Hsap\GDF2, Hsap\GDF3, Hsap\INHBC" " embryonic stage | stage >=12 , embryonic stage | stage 11,12 , embryonic stage | stage 13 , embryonic stage | stage 7-9 , embryonic stage | stage 11 , adult stage && oogenesis stage | stage >=S10 , embryonic stage | stage 9,10 , embryonic stage -- adult stage , embryonic stage | stage 5-11 " " embryonic esophagus

, embryonic foregut

, visceral mesoderm &&of posterior larval midgut

, endoderm

, visceral mesoderm &&of anterior larval midgut

, anterior midgut proper primordium

, nurse cell

, mesoderm

, embryonic hindgut

, pharynx

, oocyte

, inclusive hindgut primordium

, posterior midgut proper primordium

, organism | ubiquitous

" "neuroanatomy defective,circadian rhythm defective,heat sensitive,partially lethal - majority die,some die during pupal stage" "bouton | third instar larval stage,embryonic/larval neuromuscular junction | third instar larval stage" FBgn0011236 ken ken and barbie http://flybase.org/reports/FBgn0011236 "FBgn0010464, FBgn0010525, FBgn0020522, FBgn0024882" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype DNA binding ; GO:0003677 | inferred from mutant phenotype" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype male genitalia development ; GO:0030539 | inferred from mutant phenotype insemination ; GO:0007320 | inferred from mutant phenotype female genitalia development ; GO:0030540 | inferred from mutant phenotype female analia development ; GO:0045497 | inferred from mutant phenotype male analia development ; GO:0045496 | inferred from mutant phenotype copulation ; GO:0007620 | non-traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "l(2)00628, P420, 8253, 5029, 3907, 2970, ok, okina, l(2)05029, l(2)02970, CG5575, ken, Ken, BCL-6/KEN, KEN" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type" CG5575 11-Aug-17 DroID_v2017_08 Drer\mynn "Scer\ACE2, Scer\CMR3, Scer\MSN2, Scer\COM2, Scer\STE12, Scer\YPR015C, Scer\SWI5" "Cele\F58G1.2, Cele\K11D12.12, Cele\lir-1, Cele\lir-3, Cele\lir-2, Cele\slr-2, Cele\hinf-1, Cele\tra-4, Cele\ztf-1, Cele\lin-26" - "Mmus\Zbtb17, Mmus\Zfp174" "Hsap\ZSCAN16, Hsap\ZNF174" " embryonic stage | stage 16 , embryonic stage | stage 6-7 , embryonic stage | stage 5-7 , larval stage | third instar , embryonic stage | stage 5 , embryonic stage | stage 15 , embryonic stage -- adult stage , embryonic stage | stage 6-15 , embryonic stage " " dorsal pouch

, cephalic furrow | posterior to

, embryonic/larval foregut

, organism | 20% egg length

, genital disc

, organism | 20% egg length & 70% egg length

, embryonic foregut

, embryonic/larval hindgut

, eye-antennal disc

, organism

, embryonic/larval proventriculus

, tracheal system

, anal pad

, embryonic hindgut

, embryonic/larval posterior spiracle

, organism | 60% egg length

" "visible,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,lethal,recessive,dominant,somatic clone" "rhabdomere R7,terminalia,male genital disc,male genitalia,female genitalia,vulva,female analia,arista,female gonopod,penis,clasper,genitalia,antenna,embryonic/larval posterior spiracle,wing margin bristle,somatic clone,tracheal pit" FBgn0264270 Sxl Sex lethal http://flybase.org/reports/FBgn0264270 protein_coding_gene "poly(U) RNA binding ; GO:0008266 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity translation repressor activity, nucleic acid binding ; GO:0000900 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Sin growth factor activity ; GO:0008083 | inferred from direct assay mRNA 5'-UTR binding ; GO:0048027 | inferred from direct assay mRNA 5'-UTR binding ; GO:0048027 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with snf mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay poly-pyrimidine tract binding ; GO:0008187 | inferred from direct assay mRNA binding ; GO:0003729 | traceable author statement" "sex determination ; GO:0007530 | inferred from electronic annotation with InterPro:IPR006546 sex determination ; GO:0007530 | non-traceable author statement sex determination ; GO:0007530 | traceable author statement regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from direct assay female germ-line sex determination ; GO:0019099 | traceable author statement female somatic sex determination ; GO:0019101 | traceable author statement imaginal disc growth ; GO:0007446 | inferred from mutant phenotype dosage compensation ; GO:0007549 | traceable author statement negative regulation of translation ; GO:0017148 | traceable author statement smoothened signaling pathway ; GO:0007224 | inferred from direct assay negative regulation of mRNA splicing, via spliceosome ; GO:0048025 | traceable author statement sex differentiation ; GO:0007548 | traceable author statement negative regulation of translation ; GO:0017148 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | traceable author statement negative regulation of translation ; GO:0017148 | non-traceable author statement somatic sex determination ; GO:0018993 | traceable author statement somatic sex determination ; GO:0018993 | non-traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | traceable author statement sex differentiation ; GO:0007548 | non-traceable author statement alternative mRNA splicing, via spliceosome ; GO:0000380 | traceable author statement female sex determination ; GO:0030237 | non-traceable author statement regulation of mRNA splicing, via spliceosome ; GO:0048024 | traceable author statement oocyte differentiation ; GO:0009994 | inferred from direct assay dosage compensation ; GO:0007549 | non-traceable author statement oogenesis ; GO:0048477 | traceable author statement sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement negative regulation of translation ; GO:0017148 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with snf "SXL, Sxl, sxl, CG33070, CG14425/CG18350, CG43770, melSxl, CG18350, dSXL, Sx1, DmSxl, Sxl-1 Sxl-2, fs(1)M106, l(1)6Fa, fs(1)K1274, Su(da), Mex156, Fl, SxlPe, SxL, SxlPm, CG14425, ORF2" "IPR000504:RNA recognition motif domain, IPR002343:Paraneoplastic encephalomyelitis antigen, IPR006546:Sex-lethal splicing factor" CG43770 11-Aug-17 DroID_v2017_08 "Drer\elavl2, Drer\hug" "Scer\PAB1, Scer\GBP2" "Cele\eif-3.G, Cele\exc-7" "Xtro\elavl2, Xtro\elavl4, Xtro\elavl3, Xtro\elavl1" "Mmus\Elavl1, Mmus\Elavl2, Mmus\Elavl3, Mmus\Elavl4" "Hsap\ELAVL4, Hsap\ELAVL3, Hsap\ELAVL2, Hsap\ELAVL1" embryonic stage | embryonic cycle 12-14 " embryonic stage | male , embryonic stage | female " " organism | 50-100% egg length

,

0-55% egg length{ + schb.P } ,

0-100% egg length{ - hhb.P } " DRSC21490 IK -0.732353843 -2.48634286 -0.800901194 1.193402481 3.362931469 2.615196174 FBgn0015295 Shark SH2 ankyrin repeat kinase http://flybase.org/reports/FBgn0015295 "FBgn0004605, FBgn0010286, FBgn0028603, FBgn0034090" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357" "maintenance of epithelial cell apical/basal polarity ; GO:0045199 | inferred from expression pattern eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from mutant phenotype inferred from genetic interaction with Jra sleep ; GO:0030431 | inferred from expression pattern JNK cascade ; GO:0007254 | non-traceable author statement apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from biological aspect of ancestor with PANTHER:PTN001231165 dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype inferred from genetic interaction with bwk innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 dorsal closure ; GO:0007391 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype dorsal closure, elongation of leading edge cells ; GO:0007394 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype" cell cortex ; GO:0005938 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 cytoplasm ; GO:0005737 | inferred from direct assay "Shark, SHARK, CG18247, SYK/SHARK, dtk7, l(2R)W4, l(2)W4, Tk7, Dtk7, shark, Syk" "IPR000719:Protein kinase domain, IPR000980:SH2 domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR002110:Ankyrin repeat, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR020683:Ankyrin repeat-containing domain" CG18247 11-Aug-17 DroID_v2017_08 "Drer\ptk2aa, Drer\syk, Drer\zap70" - - "Xtro\syk, Xtro\zap70" "Mmus\Zap70, Mmus\Syk" "Hsap\SYK, Hsap\ZAP70" " larval stage | third instar , embryonic stage | 0-12hr " imaginal disc

" embryonic stage , embryonic stage | stage 8-9 , embryonic stage | stage 7-9 , embryonic stage | stage 10-11 , embryonic stage | late , embryonic stage | stage 7 " " gnathal segment

, embryonic/larval esophagus

, frontal head air sac

, stomodeum

, cephalic furrow

, inclusive hindgut primordium

, embryonic/larval pharynx

, invaginating stomatogastric nervous system precursor

, proctodeum

, embryonic/larval foregut

, atrium

, embryonic/larval salivary gland

, embryonic/larval hindgut

, embryonic/larval tracheal system

, ventral midline

" "wild-type,lethal,recessive,germline clone,rescuable maternal effect,viable,cell death defective" "ensheathing neuropil associated glial cell,wing,adult thorax,dorsal,dorsal closure embryo,germline clone,embryonic epidermis,dorsal appendage,somatic clone,chorion | somatic clone,egg chamber,follicle cell" FBgn0025802 Sbf SET domain binding factor http://flybase.org/reports/FBgn0025802 - protein_coding_gene "phosphatase regulator activity ; GO:0019208 | inferred from electronic annotation with InterPro:IPR030567 chromatin binding ; GO:0003682 | inferred from direct assay phosphatidylinositol 3-kinase catalytic subunit binding ; GO:0036313 | inferred from physical interaction with Pi3K68D protein binding, bridging ; GO:0030674 | inferred from physical interaction with Pi3K68D, mtm, Rab21 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence or structural similarity with HGNC:2135 inferred from physical interaction with Rab21 histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | contributes_to inferred from direct assay protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from sequence model histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay phosphatase binding ; GO:0019902 | inferred from physical interaction with mtm Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab11, Rab21" regulation of GTPase activity ; GO:0043087 | inferred from electronic annotation with InterPro:IPR030567 histone acetylation ; GO:0016573 | inferred from direct assay positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype regulation of Rab protein signal transduction ; GO:0032483 | inferred from direct assay positive regulation of autophagosome maturation ; GO:1901098 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from direct assay mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype recycling endosome ; GO:0055037 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from physical interaction with trx cell cortex ; GO:0005938 | inferred from direct assay histone methyltransferase complex ; GO:0035097 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay SNARE complex ; GO:0031201 | colocalizes_with inferred from physical interaction with Vamp7 "sbf, Sbf1, SBF, CG6939, dSbf1, DSbf1, Sbf, SBF1" "IPR001194:DENN domain, IPR001849:Pleckstrin homology domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR004182:GRAM domain, IPR005112:dDENN domain, IPR005113:uDENN domain, IPR010569:Myotubularin-like phosphatase domain, IPR011993:PH domain-like, IPR030564:Myotubularin family, IPR030567:Myotubularin-related protein 13, IPR029021:Protein-tyrosine phosphatase-like, IPR022096:SBF1/SBF2 domain" CG6939 11-Aug-17 DroID_v2017_08 "Drer\mtmr10, Drer\sbf1, Drer\sbf2, Drer\mtmr11, Drer\mtmr12" Scer\YMR1 "Cele\mtm-5, Cele\Y48G1C.10, Cele\mtm-1, Cele\mtm-3" "Xtro\sbf2, Xtro\sbf1" "Mmus\Sbf1, Mmus\Mtmr11, Mmus\Mtmr10, Mmus\Sbf2, Mmus\Mtmr12" "Hsap\SBF1, Hsap\MTMR12, Hsap\MTMR10, Hsap\MTMR11, Hsap\SBF2" "lethal - all die before end of P-stage,some die during pharate adult stage" macrophage DRSC16852 E 0.388820426 -0.404144164 1.53370148 -0.554951785 -0.558314223 -0.083443024 FBgn0051615 His-Psi:CR31615 His-Psi:CR31615 http://flybase.org/reports/FBgn0051615 pseudogene_attribute - - - "bs28b08.y1, CR31615, His-Psi:CR31615" - CR31615 11-Aug-17 DroID_v2017_08 - - - - - - DRSC03760 IEK -5.165196415 -6.818911135 -3.264339282 -6.619325611 -2.847291819 -1.664703147 FBgn0040534 Sf3b5 Splicing factor 3b subunit 5 http://flybase.org/reports/FBgn0040534 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000469546 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 spermatogenesis ; GO:0007283 | inferred from mutant phenotype" U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000469546 U2 snRNP ; GO:0005686 | colocalizes_with inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG11985, sf3b5, Sf3b5" "IPR009846:Splicing factor 3B subunit 5/RDS3 complex subunit 10, IPR017089:Splicing factor 3B, subunit 5" CG11985 11-Aug-17 DroID_v2017_08 Drer\sf3b5 Scer\YSF3 Cele\moa-2 Xtro\sf3b5 Mmus\Sf3b5 Hsap\SF3B5 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC14460 IEK -0.31429718 1.81001035 -2.838171322 -0.159559576 -2.090528352 -1.112644158 FBgn0037087 CG7519 - http://flybase.org/reports/FBgn0037087 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001002363 CG7519 "IPR008476:Protein PBDC1, metazoa/fungi, IPR021148:Polysaccharide biosynthesis domain, IPR023139:Yst0336-like domain" CG7519 11-Aug-17 DroID_v2017_08 Drer\pbdc1 Scer\YPL225W Cele\Y54E5A.5 Xtro\pbdc1 Mmus\Pbdc1 Hsap\PBDC1 viable DRSC11834 K 0.53716384 0.165174244 0.694007981 0.311650415 0.145066029 1.797221802 FBgn0046247 CG5938 - http://flybase.org/reports/FBgn0046247 protein_coding_gene molecular_function ; GO:0003674 | no biological data available transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000988723 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000988723 "BEST:LD40095, CG5938" IPR019383:Golgin subfamily A member 7/ERF4 CG5938 11-Aug-17 DroID_v2017_08 "Drer\chic1, Drer\chic2" - Cele\tag-266 Xtro\chic2 "Mmus\Chic1, Mmus\Chic2" "Hsap\CHIC2, Hsap\CHIC1" "viable,fertile" DRSC24038 EK -0.351441417 -1.194784554 -1.277554129 2.150915356 1.888623144 0.524119735 FBgn0085421 Epac Exchange protein directly activated by cAMP http://flybase.org/reports/FBgn0085421 protein_coding_gene "guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from electronic annotation with InterPro:IPR001895, InterPro:IPR019804" regulation of Rap protein signal transduction ; GO:0032487 | inferred from genetic interaction with Rap1 cellular_component ; GO:0005575 | no biological data available "Epac, CG34392, CG3427, D-EPAC, CG15235, epac, Dm_2R:10367, D-Epac" "IPR018490:Cyclic nucleotide-binding-like, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR000595:Cyclic nucleotide-binding domain, IPR000591:DEP domain, IPR000159:Ras-associating (RA) domain, IPR014710:RmlC-like jelly roll fold, IPR023578:Ras guanine nucleotide exchange factor domain, IPR019804:Ras guanine-nucleotide exchange factor, conserved site, IPR029071:Ubiquitin-related domain" CG34392 11-Aug-17 DroID_v2017_08 "Drer\rapgef5b, Drer\zgc:171558, Drer\rapgef5a, Drer\rapgef3, Drer\rapgef4, Drer\rapgefl1" "Scer\CDC25, Scer\BUD5" Cele\epac-1 "Xtro\rapgef4, Xtro\rapgef3, Xtro\rapgefl1, Xtro\rapgef5" "Mmus\Rapgef5, Mmus\Rapgef4, Mmus\Rapgef3, Mmus\Rapgefl1" "Hsap\RAPGEF5, Hsap\RAPGEF4, Hsap\RAPGEF3, Hsap\RAPGEFL1" DRSC04997 I 0.308747236 1.588296712 0.621298464 0.690697768 -0.417145711 -0.03701505 FBgn0002044 swm second mitotic wave missing http://flybase.org/reports/FBgn0002044 "FBgn0019934, FBgn0032794" protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 mRNA binding ; GO:0003729 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VSK8 positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from genetic interaction with smo inferred from genetic interaction with hh negative regulation of mRNA polyadenylation ; GO:1900364 | inferred from mutant phenotype positive regulation of RNA export from nucleus ; GO:0046833 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "swm, CG10084, S(Rux)2B, S(rux)2B, l(2)37Dh, E1, l(2)E1, EC2-10, Swm" "IPR000571:Zinc finger, CCCH-type, IPR000504:RNA recognition motif domain, IPR002483:PWI domain" CG10084 11-Aug-17 DroID_v2017_08 "Drer\rbm26, Drer\rbm27" - Cele\B0336.3 Xtro\rbm27 "Mmus\Rbm27, Mmus\Rbm26" "Hsap\RBM26, Hsap\RBM27" "increased cell size,lethal,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during larval stage,recessive,mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage" "wing hair,wing,mesothoracic tergum,wing vein" DRSC21831 E 0.980770036 -0.373857575 1.919337119 0.213522389 0.743617121 1.277714198 FBgn0000581 E(Pc) Enhancer of Polycomb http://flybase.org/reports/FBgn0000581 FBgn0015874 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR024943 histone exchange ; GO:0043486 | inferred from direct assay dendrite guidance ; GO:0070983 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from direct assay chromatin organization ; GO:0006325 | inferred from mutant phenotype Piccolo NuA4 histone acetyltransferase complex ; GO:0032777 | inferred from electronic annotation with InterPro:IPR024943 histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | NOT inferred from direct assay intercalary heterochromatin ; GO:0005725 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "CG7776, GH05739, GH14582, e(Pc), III, l(2)28-28-12, anon-48Ac, E(Pc), E(PC), e(pc)" "IPR019542:Enhancer of polycomb-like, N-terminal, IPR024943:Enhancer of polycomb protein" CG7776 11-Aug-17 DroID_v2017_08 "Drer\epc1b, Drer\epc1a, Drer\epc2" Scer\EPL1 Cele\epc-1 "Xtro\epc1, Xtro\epc2" "Mmus\Epc1, Mmus\Epc2" "Hsap\EPC2, Hsap\EPC1" embryonic stage -- adult stage embryonic stage "

ubiquitous , embryonic central nervous system

" "lethal,recessive,suppressor of variegation,dominant,radiation resistant,neuroanatomy defective,decreased cell number,partially lethal - majority die,visible" "adult antennal lobe projection neuron DL1 adPN,trichogen cell,mesothoracic tergum" DRSC05281 IE 0.761096839 -4.095449321 2.03377399 -5.674167448 0.343384062 -0.366227137 FBgn0264339 CG43795 - http://flybase.org/reports/FBgn0264339 protein_coding_gene G-protein coupled GABA receptor activity ; GO:0004965 | inferred from electronic annotation with InterPro:IPR002455 "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000337, InterPro:IPR002455, InterPro:IPR017978" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000337, InterPro:IPR002455, InterPro:IPR017978" "CG43795, CG5357, CG34372, CG13552, CG13553, CG13556, CG18678, CG18679" "IPR002455:GPCR family 3, GABA-B receptor, IPR000337:GPCR, family 3, IPR017978:GPCR family 3, C-terminal" CG43795 11-Aug-17 DroID_v2017_08 "Drer\gpr158b, Drer\gpr158a, Drer\gpr156, Drer\si:ch211-156l18.8" - Cele\F39B2.8 "Xtro\gpr158, Xtro\plgrkt" "Mmus\Gpr156, Mmus\Gpr179, Mmus\Gpr158" "Hsap\GPR156, Hsap\GPR158, Hsap\GPR179" DRSC04497 E 0.575599073 0.938031731 1.722872503 -0.746215603 0.71576584 0.570156932 FBgn0035879 GAPcenA GTPase activating protein and centrosome-associated http://flybase.org/reports/FBgn0035879 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with HGNC:17155 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR033185 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:17155 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:17155 "CG7112, FBgn 35879, GAPcenA, GapcenA, FBgn0035879" "IPR000195:Rab-GTPase-TBC domain, IPR011993:PH domain-like, IPR033185:Rab GTPase-activating protein 1, IPR022164:Kinesin-like, IPR006020:PTB/PI domain" CG7112 11-Aug-17 DroID_v2017_08 "Drer\rabgap1l, Drer\rabgap1, Drer\usp6nl, Drer\si:ch211-288d18.1, Drer\si:dkeyp-19e1.3, Drer\rabgap1l2" "Scer\GYL1, Scer\GYP5" "Cele\tbc-17, Cele\tbc-11" "Xtro\rabgap1l, Xtro\rabgap1" "Mmus\Rabgap1l, Mmus\Usp6nl, Mmus\Rabgap1" "Hsap\TBC1D3F, Hsap\TBC1D26, Hsap\TBC1D3B, Hsap\USP6NL, Hsap\TBC1D3G, Hsap\TBC1D29, Hsap\TBC1D3, Hsap\TBC1D28, Hsap\TBC1D3H, Hsap\TBC1D3C, Hsap\USP6, Hsap\RABGAP1, Hsap\RABGAP1L" "viable,fertile" DRSC10771 K 0.160488008 -0.090600095 -0.105011932 -0.275681427 0.296290785 2.126304556 FBgn0037270 eIF3f1 eukaryotic translation initiation factor 3 subunit f1 http://flybase.org/reports/FBgn0037270 protein_coding_gene translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000056988 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:3275 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor binding ; GO:0031369 | inferred from biological aspect of ancestor with PANTHER:PTN000056988 positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from biological aspect of ancestor with PANTHER:PTN000056988 autophagic cell death ; GO:0048102 | inferred from expression pattern protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:3275 translational initiation ; GO:0006413 | inferred from sequence or structural similarity salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern "eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity eukaryotic translation initiation factor 3 complex, eIF3m ; GO:0071541 | inferred from biological aspect of ancestor with PANTHER:PTN000056988" "eIF3-S5, eif3f, CG9769, eIF3f, Q9VN50, eIF3f1" "IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR024969:Rpn11/EIF3F, C-terminal, IPR027531:Eukaryotic translation initiation factor 3 subunit F" CG9769 11-Aug-17 DroID_v2017_08 Drer\eif3f Scer\RPN8 Cele\eif-3.F Xtro\eif3f Mmus\Eif3f Hsap\EIF3F "lethal - all die before end of larval stage,some die during larval stage,lethal,visible,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing margin bristle" DRSC12328 IEK -2.546542727 -1.382684869 -2.736108172 -2.727027446 -0.536151743 2.223274849 FBgn0036316 CG10960 - http://flybase.org/reports/FBgn0036316 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829 plasma membrane ; GO:0005886 | inferred from direct assay" "CT30701, CG10960" "IPR003663:Sugar/inositol transporter, IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG10960 11-Aug-17 DroID_v2017_08 "Drer\slc2a13b, Drer\slc2a10, Drer\si:ch1073-263o8.2, Drer\slc2a12, Drer\slc2a8, Drer\LOC797974, Drer\si:dkey-229d11.5, Drer\slc2a6, Drer\LOC101882338" "Scer\HXT2, Scer\HXT13, Scer\GEX1, Scer\VBA5, Scer\MPH3, Scer\YMR279C, Scer\YDR387C, Scer\HXT6, Scer\SNF3, Scer\HXT17, Scer\VBA2, Scer\VBA1, Scer\AZR1, Scer\HXT4, Scer\VBA3, Scer\HXT3, Scer\RGT2, Scer\SGE1, Scer\HXT5, Scer\ENB1, Scer\HXT15, Scer\HXT8, Scer\MPH2, Scer\ITR2, Scer\STL1, Scer\ITR1, Scer\HXT16, Scer\HXT1, Scer\ATR1, Scer\GEX2, Scer\HXT10, Scer\MAL11, Scer\HXT14, Scer\VBA4, Scer\HXT7, Scer\GAL2, Scer\MAL31, Scer\HXT9, Scer\YFL040W, Scer\HXT11, Scer\YDL199C" "Cele\M01G12.14, Cele\hmit-1.1, Cele\M01G12.9, Cele\Y66D12A.21, Cele\hmit-1.2, Cele\hmit-1.3, Cele\ZK829.9" "Xtro\slc2a10, Xtro\slc2a6, Xtro\slc2a8, Xtro\slc2a12, Xtro\slc2a5" "Mmus\Tm2d1, Mmus\Pate1, Mmus\Pate3, Mmus\Slc2a10, Mmus\Gm17689, Mmus\Pate4, Mmus\Slc2a12, Mmus\Slc2a6, Mmus\Gm7257, Mmus\Gm5615, Mmus\1700013H16Rik, Mmus\Acrv1, Mmus\Slc2a8, Mmus\Slc2a5, Mmus\Slc2a13" "Hsap\SLC2A10, Hsap\SLC2A8, Hsap\SLC2A13, Hsap\ACRV1, Hsap\TM2D1, Hsap\PATE1, Hsap\PATE4, Hsap\PATE3, Hsap\SLC2A6, Hsap\SLC2A12, Hsap\SLC2A5" viable DRSC09807 IE -0.710530261 1.944183123 1.524104828 -0.125012963 0.194891443 -0.192748525 FBgn0028853 CG15263 - http://flybase.org/reports/FBgn0028853 protein_coding_gene - - - "BG:DS07851.4, CG15263" - CG15263 11-Aug-17 DroID_v2017_08 - - - - - - viable DRSC01974 E -0.124149794 0.077289846 0.519762219 1.678885748 0.092135928 0.139354468 FBgn0036391 CG17364 - http://flybase.org/reports/FBgn0036391 protein_coding_gene - - - CG17364 IPR006149:EB domain CG17364 11-Aug-17 DroID_v2017_08 - - - - - - DRSC10270 E 0.726493289 0.045649938 2.506026959 0.409955976 -0.120580456 -0.705712405 FBgn0039645 CG11898 - http://flybase.org/reports/FBgn0039645 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "Dme_CG11898, CG11898" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG11898 11-Aug-17 DroID_v2017_08 "Drer\abcc8, Drer\abcc6b.2, Drer\abcc1, Drer\abcc13, Drer\abcc6a, Drer\abcc5, Drer\abcc10, Drer\abcc3, Drer\LOC100329706, Drer\cftr, Drer\abcc2, Drer\abcc12, Drer\abcc9, Drer\abcc4" "Scer\VMR1, Scer\STE6, Scer\YOR1, Scer\YBT1, Scer\NFT1, Scer\YKR104W, Scer\BPT1, Scer\YCF1" "Cele\mrp-2, Cele\pmp-4, Cele\mrp-8, Cele\mrp-7, Cele\mrp-6, Cele\mrp-1, Cele\mrp-4, Cele\mrp-5, Cele\mrp-3" "Xtro\abcc1, Xtro\abcc6, Xtro\abcc3, Xtro\cftr, Xtro\abcc10, Xtro\abcc4" "Mmus\Abcc10, Mmus\Abcc9, Mmus\Abcc8, Mmus\Abcd2, Mmus\Abcc6, Mmus\Abcc5, Mmus\Abcc1, Mmus\Abcc4, Mmus\Cftr, Mmus\Abcc3, Mmus\Abcc12, Mmus\Abcc2" "Hsap\ABCC4, Hsap\ABCC2, Hsap\ABCC5, Hsap\CFTR, Hsap\ABCC9, Hsap\ABCC8, Hsap\ABCC12, Hsap\ABCC10, Hsap\ABCC3, Hsap\ABCD2, Hsap\ABCC11, Hsap\ABCC1, Hsap\ABCC6" "viable,fertile" DRSC14432 IK -0.979546306 -3.244484535 0.344812767 -0.245373646 -1.805421876 0.492003521 FBgn0032922 CG9249 - http://flybase.org/reports/FBgn0032922 protein_coding_gene "2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425 | inferred from electronic annotation with InterPro:IPR010233" ubiquinone biosynthetic process ; GO:0006744 | inferred from electronic annotation with InterPro:IPR010233 wound healing ; GO:0042060 | inferred from mutant phenotype - CG9249 "IPR010233:Ubiquinone biosynthesis O-methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR013216:Methyltransferase type 11" CG9249 11-Aug-17 DroID_v2017_08 Drer\coq3 Scer\COQ3 Cele\coq-3 Xtro\coq3 Mmus\Coq3 Hsap\COQ3 "viable,fertile,visible" trichogen cell DRSC03168 K -0.091416109 -0.124518509 -0.906953214 0.343887644 1.157894776 1.925676626 FBgn0016076 vri vrille http://flybase.org/reports/FBgn0016076 "FBgn0001927, FBgn0002670" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR004827 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR004827 multicellular organism development ; GO:0007275 | traceable author statement multicellular organism aging ; GO:0010259 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | non-traceable author statement cellular process ; GO:0009987 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | traceable author statement locomotor rhythm ; GO:0045475 | non-traceable author statement transcription, DNA-templated ; GO:0006351 | non-traceable author statement circadian rhythm ; GO:0007623 | inferred from direct assay rhythmic behavior ; GO:0007622 | traceable author statement positive regulation of heart contraction ; GO:0045823 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "jf23, argo, mat(2)earlyRS32, mat(2)ea-G, l(2)jf23, l(2)25Db, CG14029, vri, VRI, mel_vri, Vri, DM16" "IPR004827:Basic-leucine zipper domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG14029 11-Aug-17 DroID_v2017_08 "Drer\nfil3-6, Drer\nfil3-5, Drer\nfil3-2, Drer\nfil3, Drer\nfil3-4, Drer\si:dkey-172o19.2" - "Cele\atf-2, Cele\atf-8" "Xtro\thibz, Xtro\nfil3" Mmus\Nfil3 Hsap\NFIL3 " embryonic stage | >=4hr , embryonic stage | stage 13 , embryonic stage | stage 13-16 , embryonic stage | stage 14 , adult stage , pupal stage&&adult stage , larval stage | third instar , adult stage && oogenesis stage | stage S8 , embryonic stage | 0-8hr , embryonic stage | stage >=10 , embryonic stage | stage 15 , embryonic stage | stage 13-14 , embryonic stage | stage 16 , adult stage | male , embryonic stage | early " " posterior spiracle primordium

, anal pad

, epidermis | restricted

, ventral adult lateral neuron

, nurse cell

, dorsal adult lateral neuron

, adult head

, larval brain

, imaginal disc

, photoreceptor cell

, intercalary segment

, larval lateral neuron

, embryonic/larval proventriculus

, stomodeum

, embryonic/larval foregut

, amnioserosa

, inclusive hindgut primordium

, embryonic/larval tracheal system

,

ubiquitous , embryonic/larval digestive system

, follicle cell

" "visible,decreased cell size,somatic clone,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,lethal,locomotor rhythm defective,dominant,viable,female sterile,non-rescuable maternal effect,increased cell size,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "wing,wing margin,anterior,wing hair,embryonic dorsal epidermis,maternal effect,embryonic/larval tracheal system,head,denticle belt,wing vein L5,medial triple row,somatic clone,chaeta,eye,ommatidium,interommatidial bristle,eye photoreceptor cell stalk,extended germ band embryo,filzkorper,posterior scutellar bristle,egg,germline clone,adult heart,RU486 conditional,wing vein L2,embryonic head,embryonic/first instar larval cuticle,dorsal closure embryo,macrochaeta,supernumerary,wing disc,embryonic/larval salivary gland,embryonic/larval fat body,wing vein L3,mesothoracic tergum" DRSC23174 K 1.666600229 0.69112959 FBgn0004052 Z600 Z600 http://flybase.org/reports/FBgn0004052 "FBgn0026799, FBgn0041755" protein_coding_gene cyclin binding ; GO:0030332 | inferred from physical interaction with CycA inferred from physical interaction with CycE protein binding ; GO:0005515 | inferred from physical interaction with Nup50 gastrulation ; GO:0007369 | non-traceable author statement negative regulation of G2/M transition of mitotic cell cycle ; GO:0010972 | inferred from mutant phenotype negative regulation of mitotic nuclear division ; GO:0045839 | inferred from mutant phenotype negative regulation of mitotic nuclear division ; GO:0045839 | non-traceable author statement ventral furrow formation ; GO:0007370 | inferred from genetic interaction with stg negative regulation of mitotic nuclear division ; GO:0045839 | inferred from genetic interaction with stg cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement "z600, DMZ60MEX, 3.2, frs, CG17962, Z600, Frs" - CG17962 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | stage 5-12 , embryonic stage | >=embryonic cycle 13 , embryonic stage | stage 4 , embryonic stage | 0-4 hr " " organism | dorsal

, organism | posterior

" " embryonic stage | 0-4 hr , embryonic stage | embryonic cycle 11-13 " "mitotic cell cycle defective,decreased cell number,visible,increased cell size,viable" "spermatogonial cyst,egg chamber,organism | embryonic cycle 16prd.RG1,wing hair,wing disc,wing" FBgn0266579 tau tau http://flybase.org/reports/FBgn0266579 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with NCBI_gi:1698712 inferred from sequence or structural similarity with NCBI_gi:517394 microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN001691447 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity lateral inhibition ; GO:0046331 | inferred from mutant phenotype negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype rhabdomere morphogenesis ; GO:0061541 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity with NCBI_gi:1698712 inferred from sequence or structural similarity with NCBI_gi:517394 dendrite ; GO:0030425 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay cytoplasmic microtubule ; GO:0005881 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from biological aspect of ancestor with PANTHER:PTN001691447 "Tau, tau, CG45110, dtau, CG31057, CG12881, BcDNA:RE16764, dTau, d-tau, CG5606, CG31058, CG34294" "IPR001084:Microtubule associated protein, tubulin-binding repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG45110 11-Aug-17 DroID_v2017_08 "Drer\LOC100001114, Drer\maptb, Drer\si:dkey-77a20.5, Drer\mapta, Drer\map2" - Cele\ptl-1 "Xtro\map2, Xtro\map4, Xtro\mapt" "Mmus\Map2, Mmus\Mapt, Mmus\Map4" "Hsap\MAPT, Hsap\MAP4, Hsap\MAP2" " embryonic stage | late , adult stage , larval stage " " mesothoracic dorsal triscolopidial chordotonal organ dch3

, lamina

, eye disc

, ventral thoracic disc | restricted

, prothoracic dorsal triscolopidial chordotonal organ dch3

, abdominal 8 lateral chordotonal organ lch3

, neuron

, embryonic peripheral nervous system | restricted

, optic lobe

, medulla

, head

, embryonic brain

, abdominal lateral monoscolopidial chordotonal organ lch1

, abdominal lateral pentascolopidial chordotonal organ lch5

, abdominal 9 lateral chordotonal organ lch3/1

, ventral nerve cord

, metathoracic dorsal triscolopidial chordotonal organ dch3

, retina

, larval optic lobe

, morphogenetic furrow | posterior to

" FBgn0031485 CG9643 - http://flybase.org/reports/FBgn0031485 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR026635 - - CG9643 "IPR025714:Methyltransferase domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR026635:Protein-lysine N-methyltransferase Efm4" CG9643 11-Aug-17 DroID_v2017_08 Drer\mettl10 Scer\EFM4 "Cele\K12D9.1, Cele\F29B9.1, Cele\R08F11.4" Xtro\mettl10 Mmus\Mettl10 Hsap\METTL10 "viable,fertile" DRSC27948 K -0.041487753 0.339278709 -0.414359299 -0.164747356 2.030279496 -0.117459148 FBgn0262511 Vha44 Vacuolar H[+] ATPase 44kD subunit http://flybase.org/reports/FBgn0262511 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 hydrogen-exporting ATPase activity, phosphorylative mechanism ; GO:0008553 | inferred from biological aspect of ancestor with PANTHER:PTN000015490 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000015490" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR004907 proton transport ; GO:0015992 | inferred from sequence or structural similarity ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 "vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD:S000001563 lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN000806076 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from biological aspect of ancestor with PANTHER:PTN000015490" "vha44, CG8048, Vha44, l(2)6072, 6072, l(2)SH1339, l(2)SH2 1339, ATP6V1C" "IPR004907:ATPase, V1 complex, subunit C" CG8048 11-Aug-17 DroID_v2017_08 "Drer\atp6v1c1a, Drer\atp6v1c2, Drer\atp6v1c1b" Scer\VMA5 Cele\vha-11 "Xtro\atp6v1c1, Xtro\atp6v1c2" "Mmus\Atp6v1c1, Mmus\Atp6v1c2" "Hsap\ATP6V1C2, Hsap\ATP6V1C1" DRSC07572 K -1.187199705 0.540526949 -0.066840649 -1.305197831 1.89672237 1.899569193 FBgn0263144 bin3 bicoid-interacting protein 3 http://flybase.org/reports/FBgn0263144 protein_coding_gene RNA polymerase II transcription factor binding ; GO:0001085 | inferred from physical interaction with bcd protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P09081 snRNA binding ; GO:0017069 | inferred from direct assay methyltransferase activity ; GO:0008168 | inferred from sequence or structural similarity with SGD:S000000238 negative regulation of translation ; GO:0017148 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype methylation ; GO:0032259 | inferred from sequence or structural similarity with SGD:S000000238 developmental process ; GO:0032502 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "bin3, Bin3, CG8276, l(2)SH1014, l(2)SH2 1014" "IPR025714:Methyltransferase domain, IPR024160:Bin3-type S-adenosyl-L-methionine binding domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR010675:RNA methyltransferase bin3, C-terminal" CG8276 11-Aug-17 DroID_v2017_08 "Drer\si:ch1073-157b13.1, Drer\si, Drer\mepce" - Cele\Y17G7B.18 - "Mmus\Mepce, Mmus\Bcdin3d" "Hsap\MEPCE, Hsap\BCDIN3D" " embryonic stage | 0-4hr , embryonic stage | early "

ubiquitous DRSC04919 IK 0.193016553 -1.977320536 0.648365009 -1.395320913 -0.631665308 -1.574000233 FBgn0014018 Rel Relish http://flybase.org/reports/FBgn0014018 "FBgn0011469, FBgn0024223" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8IRY7 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 DNA binding ; GO:0003677 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay" signal transduction ; GO:0007165 | traceable author statement <> immune response ; GO:0006955 | traceable author statement <> defense response to Gram-negative bacterium ; GO:0050829 |... mutant phenotype <> peptidoglycan recognition protein signaling pathway ; GO:0061057 |... mutant phenotype <> positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 |... expression pattern <> positive regulation of innate immune response ; GO:0045089 |... mutant phenotype <> response to bacterium ; GO:0009617 | traceable author statement <> defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement <> positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 |... mutant phenotype <> innate immune response ; GO:0045087 |... direct assay <> immune response ; GO:0006955 |... mutant phenotype <> NIK/NF-kappaB signaling ; GO:0038061 |... biological aspect of ancestor with PANTHER:PTN001193216 <> I-kappaB kinase/NF-kappaB signaling ; GO:0007249 |... biological aspect of ancestor with PANTHER:PTN001193216 <> positive regulation of defense response to virus by host ; GO:0002230 |... mutant phenotype <> innate immune response ; GO:0045087 | non-traceable author statement <> positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 |... mutant phenotype <> defense response to Gram-negative bacterium ; GO:0050829 |... genetic interaction with PGRP-LE <> cellular response to DNA damage stimulus ; GO:0006974 |... mutant phenotype <> immune response ; GO:0006955 |... expression pattern <> negative regulation of stem cell proliferation ; GO:2000647 |... mutant phenotype <> positive regulation of gene expression ; GO:0010628 |... mutant phenotype <> dendrite morphogenesis ; GO:0048813 |... mutant phenotype <> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 |... mutant phenotype <> positive regulation of nitric oxide biosynthetic process ; GO:0045429 |... mutant phenotype <> cellular response to amino acid starvation ; GO:0034198 |... mutant phenotype <> defense response to virus ; GO:0051607 |... mutant phenotype <> response to bacterium ; GO:0009617 |... direct assay <> response to cytokine ; GO:0034097 |... biological aspect of ancestor with PANTHER:PTN001193216 <> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 |... direct assay <> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 |... biological aspect of ancestor with PANTHER:PTN001193216 <> positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | non-traceable author statement <> regulation of innate immune response ; GO:0045088 |... mutant phenotype inferred from genetic interaction with brm inferred from genetic interaction with mor <> positive regulation of antifungal peptide biosynthetic process ; GO:0006967 |... mutant phenotype <> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement <> Toll signaling pathway ; GO:0008063 | traceable author statement <> positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | traceable author statement <> peripheral nervous system neuron development ; GO:0048935 |... mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nuclear euchromatin ; GO:0005719 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 I-kappaB/NF-kappaB complex ; GO:0033256 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 "rel, CG11992, REL, ird4, ird, l(3)neo36, Rel, Relish, Rel/NF-kappaB, NF-kappaB, relish, RELI, NFkappaB, Rel-p110, RelA, Rel49" "IPR000451:NF-kappa-B/Dorsal, IPR002110:Ankyrin repeat, IPR002909:IPT domain, IPR008967:p53-like transcription factor, DNA-binding, IPR011539:Rel homology domain (RHD), DNA-binding domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR020683:Ankyrin repeat-containing domain, IPR033926:NFkappaB IPT domain, IPR032397:Rel homology dimerisation domain" CG11992 11-Aug-17 DroID_v2017_08 "Drer\rel, Drer\relb, Drer\rela, Drer\nfkb1, Drer\nfkb2" - Cele\shn-1 "Xtro\rel, Xtro\nfkb1, Xtro\nfkb2, Xtro\rela" "Mmus\Nfkb2, Mmus\Rel, Mmus\Nfkb1, Mmus\Relb, Mmus\Rela" "Hsap\RELB, Hsap\RELA, Hsap\REL, Hsap\NFKB1, Hsap\NFKB2" " embryonic stage | early , adult stage | female , adult stage && oogenesis stage " nurse cell

"immune response defective,viable,recessive,neuroanatomy defective,visible,fertile,lethal,increased cell death,cold sensitive,dominant,short lived,increased cell number,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,macrochaeta,mesothoracic tergum,ectopic,adult brain,lamina,cold sensitive,dorsocentral bristle,intestinal stem cell,adult posterior midgut epithelium" DRSC16819 E 0.496334294 1.222535901 -0.400910449 2.25077341 0.302072844 -0.43303548 FBgn0262871 lute lute http://flybase.org/reports/FBgn0262871 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 neurogenesis ; GO:0022008 | inferred from biological aspect of ancestor with PANTHER:PTN001229949 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001229949 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "CG5319, CG43226, anon-WO0118547.289, lute, CG14333" "IPR000210:BTB/POZ domain, IPR011705:BTB/Kelch-associated, IPR012983:PHR, IPR011333:SKP1/BTB/POZ domain" CG43226 11-Aug-17 DroID_v2017_08 "Drer\btbd3b, Drer\btbd2, Drer\btbd3a, Drer\btbd6a, Drer\btbd17b, Drer\btbd6b" Scer\YIL001W Cele\tag-30 "Xtro\btbd2, Xtro\btbd1, Xtro\btbd6, Xtro\btbd3" "Mmus\Btbd2, Mmus\Btbd17, Mmus\Btbd1, Mmus\Btbd6, Mmus\Btbd3" "Hsap\BTBD6, Hsap\BTBD17, Hsap\BTBD1, Hsap\BTBD2, Hsap\BTBD3" DRSC25911 K 0.730624677 -0.310276427 -0.779626706 -0.139702429 2.154221261 -0.130102616 FBgn0017456 Ubc84D Ubiquitin conjugating enzyme 84D http://flybase.org/reports/FBgn0017456 - protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000002466 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with SGD:S000002466 cellular_component ; GO:0005575 | no biological data available "ubc, CG12799, Ubc84D, UbcD84" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG12799 11-Aug-17 DroID_v2017_08 "Drer\ube2l3a, Drer\ube2l3b" Scer\UBC4 "Cele\ubc-24, Cele\ubc-18" Xtro\ube2l3 "Mmus\Ube2l6, Mmus\Gm10705, Mmus\Ube2l3" "Hsap\UBE2L3, Hsap\UBE2L6" viable DRSC25384 IK 1.708094409 0.802952012 1.24885621 0.383343257 6.682892325 6.840966 FBgn0003714 tko technical knockout http://flybase.org/reports/FBgn0003714 - protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:O15235 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q29RU1 courtship behavior ; GO:0007619 | traceable author statement response to hypoxia ; GO:0001666 | inferred from direct assay mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype mitochondrial translation ; GO:0032543 | traceable author statement sensory perception of sound ; GO:0007605 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:Q29RU1 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:O15235 male courtship behavior ; GO:0008049 | inferred from mutant phenotype mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:O15235 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q29RU1 "MRPS12, EG:BACH59J11.1, S12, MRP-S12, CG7925, rps12, mt-rps12, l(1)tko, mRpS12, l(1)3Ab, tko, Tko" "IPR005679:Ribosomal protein S12, bacterial-type, IPR006032:Ribosomal protein S12/S23, IPR012340:Nucleic acid-binding, OB-fold" CG7925 11-Aug-17 DroID_v2017_08 Drer\si:dkey-17e16.10 Scer\MRPS12 Cele\mrps-12 Xtro\mrps12 Mmus\Mrps12 Hsap\MRPS12 "lethal,some die during third instar larval stage,some die during second instar larval stage,wild-type,viable,female sterile,recessive,developmental rate defective,bang sensitive,neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,visible,courtship behavior defective,male,mating defective,auditory perception defective,female,cold sensitive,chemical sensitive,neurophysiology defective,male limited,behavior defective" "egg,adult antennal lobe projection neuron DL1 adPN,somatic clone,gamma Kenyon cell,macrochaeta" DRSC27125 K 0.400620664 -0.898350641 -1.15436026 0.125075653 1.423632656 2.14779984 FBgn0030350 SelG Selenoprotein G http://flybase.org/reports/FBgn0030350 protein_coding_gene molecular_function ; GO:0003674 | no biological data available calcium ion transport ; GO:0006816 | inferred from biological aspect of ancestor with PANTHER:PTN000423974 blastoderm segmentation ; GO:0007350 | inferred from direct assay embryo development ; GO:0009790 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from direct assay regulation of gastrulation ; GO:0010470 | inferred from direct assay cell redox homeostasis ; GO:0045454 | traceable author statement embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from direct assay immune system process ; GO:0002376 | inferred from biological aspect of ancestor with PANTHER:PTN001047971 endoplasmic reticulum calcium ion homeostasis ; GO:0032469 | inferred from mutant phenotype intracellular membrane-bounded organelle ; GO:0043231 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000423974 "G-rich, CG1844, dselG, BcDNA:GH03581, SelG, dselK, dSelK, SelK" IPR024491:Selenoprotein SelK/SelG CG1844 11-Aug-17 DroID_v2017_08 Drer\selk - Cele\Y41E3.8 Xtro\selk Mmus\Selenok Hsap\SELENOK "developmental rate defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" DRSC19808 I 3.865047298 1.246750564 0.351680904 0.676829115 -0.680738177 -0.465606497 FBgn0037492 CG10050 - http://flybase.org/reports/FBgn0037492 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10050 IPR005636:DTW CG10050 11-Aug-17 DroID_v2017_08 Drer\dtwd2 - - Xtro\dtwd2 Mmus\Dtwd2 Hsap\DTWD2 viable DRSC12501 I 1.825219104 0.247793754 0.142794582 0.419107609 -0.229254431 -0.125008409 FBgn0032518 RpL24 Ribosomal protein L24 http://flybase.org/reports/FBgn0032518 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000846433 assembly of large subunit precursor of preribosome ; GO:1902626 | inferred from biological aspect of ancestor with PANTHER:PTN000846433 ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG9282, anon-EST:Posey37, anon-EST:Posey242, RpL24, Rp L24, L24, RL24_DROME, Rpl24" "IPR000988:Ribosomal protein L24e-related, IPR011017:TRASH domain" CG9282 11-Aug-17 DroID_v2017_08 Drer\rpl24 "Scer\RPL24A, Scer\RPL24B" Cele\rpl-24.1 Xtro\rpl24 Mmus\Rpl24 Hsap\RPL24 DRSC28724 IEK -2.36034726 -1.632061247 0.017070946 -3.471017496 1.63370372 2.705123609 FBgn0022986 qkr58E-1 quaking related 58E-1 http://flybase.org/reports/FBgn0022986 - protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 "neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "qkr-58-E, CG3613, qrk58E-1, qkr58E-1, QKR58E-1, Qkr58E-1" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG3613 11-Aug-17 DroID_v2017_08 "Drer\khdrbs1b, Drer\qkia, Drer\qki2, Drer\khdrbs1a, Drer\qkib, Drer\khdrbs2, Drer\khdrbs3" Scer\MSL5 "Cele\asd-2, Cele\Y57G11C.36, Cele\gld-1, Cele\K07H8.9" "Xtro\khdrbs3, Xtro\qki, Xtro\khdrbs1, Xtro\khdrbs2" "Mmus\Khdrbs2, Mmus\Qk, Mmus\Khdrbs3, Mmus\Khdrbs1" "Hsap\KHDRBS3, Hsap\QKI, Hsap\KHDRBS2, Hsap\KHDRBS1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC04709 I -1.4465963 2.040712099 0.261037455 -0.355408436 -0.070910723 -0.59231784 FBgn0002573 sens senseless http://flybase.org/reports/FBgn0002573 "FBgn0011709, FBgn0027151, FBgn0036355, FBgn0052120" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement bHLH transcription factor binding ; GO:0043425 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype inferred from genetic interaction with sc inferred from genetic interaction with da neuron development ; GO:0048666 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype inferred from genetic interaction with ro peripheral nervous system development ; GO:0007422 | traceable author statement photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay sensory organ development ; GO:0007423 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement R8 cell differentiation ; GO:0045465 | non-traceable author statement sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype positive regulation of rhodopsin gene expression ; GO:0045872 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype sensory organ development ; GO:0007423 | traceable author statement compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "Sens, sens, Sen, sense, Ly, CG10714, Ly-1, 1228/04, l(3)70Ad, CG32120, sen, senseless, SENS, Ss, Gfi1, Senseless" IPR013087:Zinc finger C2H2-type CG32120 11-Aug-17 DroID_v2017_08 "Drer\prdm13, Drer\gfi1b, Drer\gfi1aa, Drer\gfi1ab" - "Cele\ztf-30, Cele\pag-3, Cele\B0310.2" "Xtro\gfi1b, Xtro\gfi1" "Mmus\Prdm13, Mmus\Gfi1, Mmus\Gfi1b" "Hsap\TIGD1, Hsap\GFI1, Hsap\PRDM13, Hsap\GFI1B" " embryonic stage | stage 11-12 , embryonic stage | stage >=11 , embryonic stage | stage 11-13 , embryonic stage | stage 10 , embryonic stage | stage 10-12 " " external sensory organ precursor cell I

, adult salivary gland primordium

, salivary gland

, external sensory organ precursor cell IIa

, external sensory organ precursor cell IIb

, lateral ectoderm | restricted

, sensory mother cell

, embryonic peripheral nervous system | restricted

" " embryonic stage | stage 11-14 , embryonic stage | stage 10-14 , larval stage | third instar , embryonic stage | stage >=11 " " salivary gland

, embryonic peripheral nervous system | restricted

, Johnston's organ

, adult salivary gland primordium

, metathoracic femoral chordotonal organ

, sensory mother cell

, mesothoracic femoral chordotonal organ

, photoreceptor cell R8

, prothoracic femoral chordotonal organ

, eye-antennal disc | restricted

, dorsal mesothoracic disc | restricted

" "visible,wild-type,lethal,recessive,cell autonomous,somatic clone,increased cell death,neuroanatomy defective,dominant,lethal - all die before end of pupal stage,some die during pupal stage" "scutellar bristle,ectopic,chordotonal organ,external sensory organ,multidendritic neuron,photoreceptor cell R8,somatic clone,cell non-autonomous,ommatidium,photoreceptor cell R7,chaeta,cell autonomous,tormogen cell,microchaeta,photoreceptor cell R2,photoreceptor cell R5,embryonic/larval salivary gland,dorsal row,ventral row,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,supernumerary,eo neuron,thecogen cell,trichogen cell,mechanosensory chaeta,postorbital bristle,trichome of the posterior wing margin,embryonic/larval oenocyte precursor,medulla,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,presumptive embryonic/larval peripheral nervous system,embryonic peripheral nervous system & neuronS122804),PNS glial cell,wing margin,wing,anterior wing margin,posterior wing margin,eye,macrochaeta,sensillum campaniformium of dorsal radius,wing sensillum,sternopleural bristle,leg sensillum,leg,distal,scutum,wing & chaetadpp.blk1,leg & chaetadpp.blk1,scutum & chaetadpp.blk1,mesothoracic bristle,microchaeta & scutellum | ectopicC5,mechanosensory sensory organ,metathoracic bristle,prothoracic tarsal bristle,interommatidial bristle,secondary pigment cell,tertiary pigment cell,axon & photoreceptor cell R7 | somatic clonetub.PU" DRSC09263 K -2.589957165 -1.789978122 FBgn0027535 botv brother of tout-velu http://flybase.org/reports/FBgn0027535 - protein_coding_gene acetylglucosaminyltransferase activity ; GO:0008375 | inferred from direct assay acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ; GO:0001888 | inferred from sequence or structural similarity with UniProtKB:Q9UBQ6 "heparan sulfate proteoglycan metabolic process ; GO:0030201 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | inferred from mutant phenotype decapentaplegic signaling pathway ; GO:0008101 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement heparin biosynthetic process ; GO:0030210 | inferred from direct assay glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from mutant phenotype heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from direct assay N-acetylglucosamine metabolic process ; GO:0006044 | inferred from sequence or structural similarity with UniProtKB:Q9UBQ6" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR015338, InterPro:IPR027674 Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model" "Dextl3, DEXT3, Botv, CG15110, BcDNA:LD21192, botv, DEXTL3, Extl3, dExt3, DExt3" "IPR004263:Exostosin-like, IPR015338:Exostosin , C-terminal, IPR029044:Nucleotide-diphospho-sugar transferases" CG15110 11-Aug-17 DroID_v2017_08 Drer\extl3 - Cele\rib-2 Xtro\extl3 Mmus\Extl3 Hsap\EXTL3 " adult stage | male , embryonic stage -- adult stage , adult stage | female " head

"lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,body color defective" "eye,leg,imaginal disc,wing disc,wing,somatic clone,wing vein,wing margin,embryonic/first instar larval cuticle,germline clone,maternal effect,denticle belt,mesothoracic tergum" FBgn0261930 vnd ventral nervous system defective http://flybase.org/reports/FBgn0261930 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor binding ; GO:0008134 | inferred from physical interaction with D RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay" brain development ; GO:0007420 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype pattern specification process ; GO:0007389 | non-traceable author statement ventral cord development ; GO:0007419 | non-traceable author statement dorsal/ventral pattern formation ; GO:0009953 | traceable author statement glial cell development ; GO:0021782 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay neuroblast development ; GO:0014019 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype ventral cord development ; GO:0007419 | traceable author statement brain development ; GO:0007420 | traceable author statement central nervous system development ; GO:0007417 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "vnd, vnd/NK-2, EG:118B3.1, CG6172, NK-2, VND, Vnd, dNK-2, l(1)1Bf, NK2, EC6, nk-2, lab, l(1)VE769, l(1)VA208, l(1)RC24, l(1)GA122, l(1)GA100, l(1)EC6, l(1)EA142, Dm-NK2, Nkx2, HDC16822, Dm vnd" "IPR020479:Homeobox domain, metazoa, IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG6172 11-Aug-17 DroID_v2017_08 "Drer\nkx2.2a, Drer\nkx2.3, Drer\meox2a, Drer\nkx2.5, Drer\nkx2.1, Drer\meox2b, Drer\nkx2.4a, Drer\nkx2.2b, Drer\nkx2.9, Drer\nkx2.4b, Drer\nkx3.2, Drer\nkx3-1, Drer\nkx2.7, Drer\meox1, Drer\nkx3.3" - "Cele\ceh-27, Cele\ceh-22" "Xtro\nkx2-1, Xtro\nkx3-1, Xtro\nkx2-3, Xtro\nkx3-2, Xtro\nkx2-2, Xtro\nkx2-6, Xtro\nkx3-3, Xtro\nkx2-5, Xtro\nkx2-8" "Mmus\Nkx2-3, Mmus\Nkx3-2, Mmus\Nkx2-4, Mmus\Nkx2-2, Mmus\Nkx2-1, Mmus\Nkx2-5, Mmus\Nkx3-1, Mmus\Nkx2-9, Mmus\Nkx2-6" "Hsap\NKX2-1, Hsap\NKX2-8, Hsap\NKX3-2, Hsap\NKX3-1, Hsap\NKX2-2, Hsap\NKX2-5, Hsap\NKX2-6, Hsap\NKX2-4, Hsap\NKX2-3" " embryonic stage | stage 11 , embryonic stage | stage 8-11 , embryonic stage | stage >=10 , embryonic stage | stage >=13 , embryonic stage | stage 7-8 , embryonic stage | stage 7,8 " " neuroblast NB1-2

, neuroblast NB2-1

, ventral neurogenic region | restricted

, neuroblast NB4-1

, central nervous system | restricted

, posterior embryonic/larval midgut

, ventral neurogenic region

, neuroblast | subset

, neuroblast NB2-2

, neuroblast NB1-1

, anterior embryonic/larval midgut

, neuroblast NB6-2

, neuroblast NB5-2

, neuroblast NB3-1

, neuroblast NB6-1

, ventral midline

, neuroblast MP2

, neuroblast NB5-1

, neuroblast NB7-2

, neuroblast NB7-1

" " embryonic stage | stage 11 , embryonic stage | stage 8-9 , embryonic stage | stage 9-11 , embryonic stage | stage 8 , embryonic stage | cellular blastoderm " " pCC neuron

, U neuron

, embryonic neuron | subset

, neuroblast | subset

, procephalic neuroblast | subset & ventral

, protocerebral neuroblast | subset

, tritocerebral neuroblast | subset

, ventral midline

, ventral neurogenic region && embryonic antennal segment | ventral & restricted

, deuterocerebral neuroblast | subset

, ventral neurogenic region | restricted

, ventral neurogenic region && embryonic intercalary segment | ventral & restricted

, ventral neurogenic region && embryonic ocular segment | ventral & restricted

" DRSC18849 I -0.241859869 2.117121463 0.355150963 0.282667908 0.720278343 0.92449675 FBgn0026309 aft adrift http://flybase.org/reports/FBgn0026309 FBgn0028739 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR002877 "methylation ; GO:0032259 | inferred from electronic annotation with InterPro:IPR002877 open tracheal system development ; GO:0007424 | inferred from expression pattern tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement cell migration ; GO:0016477 | non-traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement" nucleus ; GO:0005634 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement "EG:52C10.7, CG5032, aft" "IPR002877:Ribosomal RNA methyltransferase FtsJ domain, IPR025807:Adrift-type ribose 2-O-methyltransferase domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG5032 11-Aug-17 DroID_v2017_08 "Drer\fdxr, Drer\cmtr2" - "Cele\Y40D12A.1, Cele\Y62E10A.6" "Xtro\cmtr2, Xtro\fdxr" "Mmus\Fdxr, Mmus\Cmtr2" "Hsap\CMTR2, Hsap\FDXR" " embryonic stage | stage >=12 , embryonic stage , embryonic stage | syncytial blastoderm , embryonic stage | stage >=11 " " embryonic/larval ganglionic branch | restricted

, gonad

,

ubiquitous , embryonic/larval tracheal system

" " embryonic stage , embryonic stage | early " " epidermis

, gonad

, embryonic brain

" "wild-type,viable" embryonic/larval ganglionic branch FBgn0263773 fok fledgling of Klp38B http://flybase.org/reports/FBgn0263773 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "fok, CG43690, 38B.11, CG10746, Fok, l(2)k07614, noncoding_3938, CG42849" - CG43690 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage&&adult stage , embryonic stage | >=4 hr , adult stage " DRSC23907 IK -1.656657316 0.333239024 -0.558448272 0.41287203 0.968085545 2.277447487 FBgn0027111 miple1 midkine and pleiotrophin 1 http://flybase.org/reports/FBgn0027111 FBgn0027731 protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR020090 heparin binding ; GO:0008201 | inferred from sequence or structural similarity with HGNC:6972 heparin binding ; GO:0008201 | inferred from direct assay mesoderm morphogenesis ; GO:0048332 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay "anon-EST:Posey203, CG1221, miple1, miple, Miple" "IPR020090:Pleiotrophin/Midkine, C-terminal domain" CG1221 11-Aug-17 DroID_v2017_08 - - - - - - "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC08722 E 0.335569321 1.166520862 1.718786772 -0.049063239 -0.556742077 -0.26566344 FBgn0085382 CG34353 - http://flybase.org/reports/FBgn0085382 protein_coding_gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - "CG34353, CG12274, CG12427, CG12873, CG12874, CG12875, CG5566, CG5572" "IPR013098:Immunoglobulin I-set, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype" CG34353 11-Aug-17 DroID_v2017_08 "Drer\esama, Drer\negr1, Drer\si:dkey-11p23.7, Drer\zgc:153911, Drer\zgc:110372, Drer\f11r.1, Drer\opcml, Drer\ntm, Drer\jam2a, Drer\vsig8a, Drer\gpa33, Drer\mxra8a, Drer\si:dkey-65b12.12, Drer\jam3b, Drer\zgc:153073, Drer\lsamp, Drer\mxra8b, Drer\cxcr3.1, Drer\cxadr, Drer\vsig8b, Drer\si:dkey-250k15.10, Drer\igsf11, Drer\jam2b, Drer\f11r.2, Drer\esamb, Drer\si:zfos-1011f11.1, Drer\jam3a" - "Cele\wrk-1, Cele\rig-5" "Xtro\negr1, Xtro\lsamp, Xtro\ntm" "Mmus\Fgfrl1, Mmus\Gm1123, Mmus\Esam, Mmus\Cxadr, Mmus\Lsamp, Mmus\Gpa33, Mmus\Jam2, Mmus\Clmp, Mmus\F11r, Mmus\Jam3, Mmus\Opcml, Mmus\Vsig1, Mmus\Mxra8, Mmus\Vsig2, Mmus\Negr1, Mmus\Vsir, Mmus\Iglon5, Mmus\Vsig8, Mmus\Hepacam2, Mmus\Igsf5, Mmus\Ntm, Mmus\Igsf11" "Hsap\NEGR1, Hsap\CXADR, Hsap\MXRA8, Hsap\VSIG8, Hsap\CLMP, Hsap\SIGLEC15, Hsap\GPA33, Hsap\ESAM, Hsap\VSIG2, Hsap\LSAMP, Hsap\OPCML, Hsap\JAM2, Hsap\JAM3, Hsap\IGLON5, Hsap\IGSF11, Hsap\C1orf204, Hsap\F11R, Hsap\IGSF5, Hsap\NTM, Hsap\VSIG1, Hsap\C10orf54" "gravitaxis defective,viable,visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC14563 K -0.037482181 0.020583236 -0.135663034 -0.190642201 2.445820845 -0.480378421 FBgn0025578 Lcp9 Larval cuticle protein 9 http://flybase.org/reports/FBgn0025578 FBgn0035062 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of chitin-based larval cuticle ; GO:0008010 | non-traceable author statement structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model larval chitin-based cuticle development ; GO:0008363 | non-traceable author statement extracellular region ; GO:0005576 | non-traceable author statement extracellular matrix ; GO:0031012 | inferred from sequence model "LCP9, CG16914, Lcp9, DmelLcp9, lcp9" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG16914 11-Aug-17 DroID_v2017_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable DRSC04287 I -0.327492265 -1.653052684 -1.240325872 0.003798219 -0.601591682 -0.666885759 FBgn0026378 Rep Rab escort protein http://flybase.org/reports/FBgn0026378 - protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 GDP-dissociation inhibitor activity ; GO:0005092 | inferred from electronic annotation with InterPro:IPR018203 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001738 small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR018203 neurotransmitter secretion ; GO:0007269 | non-traceable author statement protein geranylgeranylation ; GO:0018344 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | non-traceable author statement perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P32864 synaptic vesicle ; GO:0008021 | non-traceable author statement aster ; GO:0005818 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with UniProtKB:P32864 spindle pole ; GO:0000922 | inferred from direct assay Rab-protein geranylgeranyltransferase complex ; GO:0005968 | colocalizes_with inferred from direct assay "REP, CG8432, Rep" "IPR018203:GDP dissociation inhibitor, IPR001738:Rab protein geranylgeranyltransferase component A, IPR023753:FAD/NAD(P)-binding domain" CG8432 11-Aug-17 DroID_v2017_08 Drer\chm "Scer\GDI1, Scer\MRS6" Cele\rep-1 Xtro\chm "Mmus\Chm, Mmus\Chml" "Hsap\CHML, Hsap\CHM" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC07526 K -0.486307421 -0.918564052 -0.99137153 -0.791171118 2.081170851 -0.613765693 FBgn0013746 alien alien http://flybase.org/reports/FBgn0013746 "FBgn0027056, FBgn0063164" protein_coding_gene ligand-dependent nuclear receptor binding ; GO:0016922 | inferred from physical interaction with EcR transcription corepressor activity ; GO:0003714 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with alien nuclear hormone receptor binding ; GO:0035257 | inferred from physical interaction with EcR protein binding ; GO:0005515 | inferred from physical interaction with CSN5 inferred from physical interaction with CSN7 "regulation of cell cycle ; GO:0051726 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from sequence or structural similarity with HGNC:30747 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype multicellular organism development ; GO:0007275 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay COP9 signalosome ; GO:0008180 | inferred from direct assay COP9 signalosome ; GO:0008180 | non-traceable author statement COP9 signalosome ; GO:0008180 | inferred from direct assay inferred from physical interaction with CSN5 inferred from physical interaction with CSN7 repressor ecdysone receptor complex ; GO:0008231 | inferred from physical interaction with EcR "Dch2, CSN2, Alien, DCH2, CH2, CG9556, BcDNA:LD10463, alien, Csn2" "IPR000717:Proteasome component (PCI) domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain" CG9556 11-Aug-17 DroID_v2017_08 Drer\cops2 Scer\RPN6 Cele\csn-2 Xtro\cops2 Mmus\Cops2 Hsap\COPS2 embryonic stage " apodeme &&of pharynx

, abdominal 1--7 intrasegmental apodeme 2

, intersegmental apodeme

, intrasegmental apodeme

, abdominal 1--7 intersegmental apodeme

, abdominal 1--7 intrasegmental apodeme 1

" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC03482 K -0.360968071 -0.198849767 -0.142635149 0.796914536 1.889659677 3.183688602 FBgn0024330 MED6 Mediator complex subunit 6 http://flybase.org/reports/FBgn0024330 "FBgn0027700, FBgn0037748, FBgn0063159" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P91641 inferred from physical interaction with UniProtKB:Q9V439 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly ; GO:0001128 | inferred from biological aspect of ancestor with PANTHER:PTN000318543 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8IH24 inferred from physical interaction with UniProtKB:Q9VS38 inferred from physical interaction with UniProtKB:Q9VT57 inferred from physical interaction with UniProtKB:Q9W0P8 transcription coactivator activity ; GO:0003713 | contributes_to inferred from direct assay negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype RNA polymerase II transcriptional preinitiation complex assembly ; GO:0051123 | inferred from biological aspect of ancestor with PANTHER:PTN000318543 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype mediator complex ; GO:0016592 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN000318543 mediator complex ; GO:0016592 | inferred from sequence or structural similarity "Med6, dMED6, p35, dTRAP32, dMed6, anon-EST:Posey279, Trap32, CG9473, BcDNA:LD15729, MED6, med6" "IPR007018:Mediator complex, subunit Med6, IPR016820:Mediator complex, subunit Med6, metazoa/plant" CG9473 11-Aug-17 DroID_v2017_08 Drer\med6 Scer\MED6 "Cele\mdt-6, Cele\sna-1" Xtro\med6 Mmus\Med6 Hsap\MED6 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,female sterile,germline clone,recessive,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during third instar larval stage,lethal" "chaeta,supernumerary,trichogen cell,mesothoracic tergum,follicle cell,somatic clone,eye,imaginal disc,wing disc" DRSC16500 IK 0.112603655 2.266391193 -0.306104213 0.129206078 1.546150606 0.348712307 FBgn0267821 da daughterless http://flybase.org/reports/FBgn0267821 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ac inferred from physical interaction with l(1)sc inferred from physical interaction with sc RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from physical interaction with ase inferred from physical interaction with l(1)sc inferred from physical interaction with sc protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with amos protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ase inferred from physical interaction with l(1)sc inferred from physical interaction with sc protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with HLH54F RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | contributes_to inferred from physical interaction with ato protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with l(1)sc protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ac inferred from physical interaction with emc inferred from physical interaction with l(1)sc inferred from physical interaction with sc transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with sc transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with l(1)sc inferred from physical interaction with sc RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from physical interaction with ey transcription factor binding ; GO:0008134 | inferred from genetic interaction with E(spl)m7-HLH inferred from genetic interaction with E(spl)mγ-HLH RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000927455 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with da transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ato bHLH transcription factor binding ; GO:0043425 | inferred from biological aspect of ancestor with PANTHER:PTN000927455 DNA binding ; GO:0003677 | traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:P10627 RNA polymerase II regulatory region DNA binding ; GO:0001012 | contributes_to inferred from physical interaction with amos" "neurogenesis ; GO:0022008 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype sex determination ; GO:0007530 | traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement ovarian follicle cell development ; GO:0030707 | traceable author statement nervous system development ; GO:0007399 | traceable author statement somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype sex determination ; GO:0007530 | non-traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype positive regulation of neuron differentiation ; GO:0045666 | inferred from biological aspect of ancestor with PANTHER:PTN000927455 positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | traceable author statement neuron fate commitment ; GO:0048663 | inferred from mutant phenotype R8 cell fate specification ; GO:0045464 | non-traceable author statement oogenesis ; GO:0048477 | traceable author statement cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype inferred from genetic interaction with sens inferred from genetic interaction with sc neuroendocrine cell differentiation ; GO:0061101 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with l(1)sc "da, Da, CG5102, l(2)31Ea, bHLHb22, 5102, DA, l(2)k08611, SC_DA" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG5102 11-Aug-17 DroID_v2017_08 "Drer\tcf3a, Drer\LOC101883970, Drer\tcf3b, Drer\tcf4, Drer\tcf12" - Cele\hlh-2 "Xtro\tcf4, Xtro\tcf12, Xtro\tcf3" "Mmus\Tcf12, Mmus\Tcf3, Mmus\Tcf4" "Hsap\TCF3, Hsap\TCF12, Hsap\TCF4" DRSC03517 K -0.214533458 -0.481346584 -0.38401039 -0.59714716 1.88625726 0.524335697 FBgn0086675 fne found in neurons http://flybase.org/reports/FBgn0086675 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity poly(U) RNA binding ; GO:0008266 | inferred from direct assay regulation of mRNA processing ; GO:0050684 | inferred from genetic interaction with elav regulation of RNA metabolic process ; GO:0051252 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "fne, CG4396, Fne, cg4396, CR32646, MRE28, BEST:HL02010, BcDNA:RE25290, BcDNA:HL02010, FNE, lincRNA.985" "IPR006548:Splicing factor ELAV/HuD, IPR002343:Paraneoplastic encephalomyelitis antigen, IPR000504:RNA recognition motif domain" CG4396 11-Aug-17 DroID_v2017_08 "Drer\elavl1, Drer\hug, Drer\nol8, Drer\fam213b, Drer\rbms3, Drer\rbms2b, Drer\elavl3, Drer\rbms1a, Drer\elavl2, Drer\rbms2a, Drer\elavl4" "Scer\GBP2, Scer\PAB1" Cele\exc-7 "Xtro\elavl3, Xtro\elavl1, Xtro\elavl2, Xtro\elavl4" "Mmus\Rbms2, Mmus\Fam213b, Mmus\Elavl4, Mmus\Rbms3, Mmus\Elavl1, Mmus\Rbms1, Mmus\Elavl3, Mmus\Elavl2" "Hsap\ELAVL4, Hsap\RBMS2, Hsap\ELAVL2, Hsap\RBMS3, Hsap\ELAVL1, Hsap\FAM213B, Hsap\ELAVL3, Hsap\RBMS1" DRSC20332 IK 0.642261473 -2.601554176 -0.358408268 -0.67421499 -1.500464561 2.034815472 FBgn0039509 bigmax bigmax http://flybase.org/reports/FBgn0039509 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor binding ; GO:0008134 | inferred from electronic annotation with InterPro:IPR032647 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001039502" "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern adult feeding behavior ; GO:0008343 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with Max" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 "CG3350, DmMlx, BIGMAX, bigmax, Bigmax, Mlx, mlx, bHLHd13, cg3350" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR032647:Max-like protein X" CG3350 11-Aug-17 DroID_v2017_08 Drer\mlx "Scer\HMS1, Scer\RTG3" Cele\mxl-2 Xtro\mlx Mmus\Mlx Hsap\MLX "majority die during pharate adult stage,developmental rate defective,lethal,conditional,viable,fertile,partially lethal" DRSC27542 K -0.293881812 0.676708658 -0.386991031 -0.226091023 -1.549114853 -1.001737909 FBgn0022943 Cbp20 cap binding protein 20 http://flybase.org/reports/FBgn0022943 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA cap binding ; GO:0000339 | inferred from biological aspect of ancestor with PANTHER:PTN000428749 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V9K7 "mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from electronic annotation with InterPro:IPR027157 gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype primary miRNA processing ; GO:0031053 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000428749 negative regulation of viral genome replication ; GO:0045071 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000006099 RNA interference ; GO:0016246 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000006099 precatalytic spliceosome ; GO:0071011 | inferred from direct assay nuclear cap binding complex ; GO:0005846 | inferred from biological aspect of ancestor with PANTHER:PTN000428749 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG12357, CBP20, Cbp20, cbp20" "IPR000504:RNA recognition motif domain, IPR034148:NCBP2, RNA recognition motif, IPR027157:Nuclear cap-binding protein subunit 2" CG12357 11-Aug-17 DroID_v2017_08 "Drer\ncbp2, Drer\tmem67" Scer\CBC2 "Cele\ncbp-2, Cele\mks-3" "Xtro\ncbp2, Xtro\tmem67" "Mmus\Tmem67, Mmus\Ncbp2" Hsap\NCBP2 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16601 E -1.373373642 0.163633029 -0.665405551 -2.095003137 -0.705169843 0.013278262 FBgn0011674 insc inscuteable http://flybase.org/reports/FBgn0011674 "FBgn0010601, FBgn0013468, FBgn0015387" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with corn cytoskeletal adaptor activity ; GO:0008093 | inferred from sequence or structural similarity inferred from mutant phenotype basal protein localization ; GO:0045175 | traceable author statement apical protein localization ; GO:0045176 | inferred from mutant phenotype inferred from physical interaction with corn establishment of mitotic spindle localization ; GO:0040001 | non-traceable author statement peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | traceable author statement protein localization ; GO:0008104 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | traceable author statement establishment of mitotic spindle localization ; GO:0040001 | traceable author statement asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with Gαi inferred from genetic interaction with pins regulation of asymmetric cell division ; GO:0009786 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | non-traceable author statement sensory organ development ; GO:0007423 | traceable author statement asymmetric protein localization involved in cell fate determination ; GO:0045167 | traceable author statement neuroblast fate determination ; GO:0007400 | inferred from direct assay regulation of nervous system development ; GO:0051960 | inferred from mutant phenotype protein localization ; GO:0008104 | non-traceable author statement Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | traceable author statement establishment of mitotic spindle localization ; GO:0040001 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype RNA localization ; GO:0006403 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | traceable author statement apical cortex ; GO:0045179 | inferred from direct assay apical part of cell ; GO:0045177 | non-traceable author statement apical cortex ; GO:0045179 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "insc, Ins, nem, l(2)k12405, l(2)05475, 25/17, fam, CG11312, Insc, INSC" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG11312 11-Aug-17 DroID_v2017_08 - - Cele\insc-1 - Mmus\Insc Hsap\INSC " embryonic stage | 3-12 hr , embryonic stage | stage <=14 , embryonic stage | stage 13-15 , embryonic stage | stage 10 , embryonic stage | stage 9-11 , embryonic stage | stage 10-12 , embryonic stage | stage >=15 , embryonic stage | stage 4 , embryonic stage | 4-20 hr , embryonic stage | stage 11-13 , adult stage , embryonic stage | stage 10-13 , embryonic stage , embryonic stage | stage 6 " " embryonic central nervous system

, embryonic/larval midgut

, ganglion mother cell

, ventral neurogenic region

, posterior midgut proper primordium

, embryonic/larval hindgut

, procephalic neurogenic region

, sense organ | precursor

, embryonic peripheral nervous system | restricted

, gastric caecum

, myoblast &&of larval muscle system

, embryonic brain

, anterior midgut proper primordium

, embryonic/larval trachea

, Malpighian tubule

, ventral nerve cord | restricted

, neuroblast

, C1 chordotonal organ precursor cell

, embryonic/larval pharynx

" " embryonic stage | stage 13-15 , embryonic stage | stage 10-12 , embryonic stage | stage >=15 , embryonic stage | stage 10-13 , embryonic stage | stage 11-13 , embryonic stage | stage 6 , embryonic stage , embryonic stage | stage 10 , embryonic stage | stage 9-11 , pupal stage | >20 hr " " embryonic/larval midgut

, anterior midgut proper primordium

, embryonic/larval pharynx

, myoblast &&of larval muscle system

, sense organ | precursor

, embryonic/larval hindgut

, procephalic neurogenic region

, ventral nerve cord | restricted

, ganglion mother cell

, posterior midgut proper primordium

, neuroblast

, dorsal mesothoracic disc | restricted

, Malpighian tubule

, gastric caecum

, embryonic/larval trachea

" "lethal,recessive,viable,fertile,some die during immature adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,wild-type,neuroanatomy defective,somatic clone,cell polarity defective" "wing,presumptive embryonic/larval peripheral nervous system,chordotonal organ,imaginal disc,scutellar bristle,tormogen cell,trichogen cell,embryonic/larval somatic muscle,pericardial cell,mesothoracic lateral longitudinal muscle,abdominal dorsal oblique muscle,abdominal dorsal transverse muscle,abdominal lateral transverse muscle,abdominal adult muscle precursor cell,abdominal 1 lateral adult muscle precursor cell,abdominal 2 lateral adult muscle precursor cell,abdominal 3 lateral adult muscle precursor cell,abdominal 4 lateral adult muscle precursor cell,abdominal 5 lateral adult muscle precursor cell,abdominal 6 lateral adult muscle precursor cell,abdominal 7 lateral adult muscle precursor cell,mesothoracic ventral oblique muscle,abdominal ventral oblique muscle,somatic muscle,hypodermal muscle of larval abdominal 9,abdominal lateral pentascolopidial chordotonal organ,metathoracic ventral oblique muscle,abdominal ventral longitudinal muscle,metathoracic ventral longitudinal muscle,mesothoracic ventral longitudinal muscle,mesothoracic segment border muscle,metathoracic segment border muscle,abdominal segment border muscle,abdominal lateral longitudinal muscle,Malpighian tubule tip cell,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,abdominal dorsal acute muscle,dorsal oblique muscle,prothoracic dorsal oblique muscle,mesothoracic dorsal oblique muscle,metathoracic dorsal oblique muscle,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle,abdominal anterior ventral multidendritic neuron vdaa,abdominal vesA neuron,abdominal v'esA neuron,abdominal vesB neuron,abdominal v'esB neuron,abdominal vesC neuron,ventral multidendritic neuron vdaA,ventral multidendritic neuron vdaB,ventral multidendritic neuron vdaC,ventral multidendritic neuron vdaD,abdominal ventral bipolar neuron vbp,adult muscle precursor cell,ganglion mother cell GMC1-1a,ganglion mother cell GMC4-2a,pCC neuron,RP2sib neuron,abdominal ventral multidendritic neuron,neuroblast,RP2 motor neuron,aCC neuron,U neuron,EL neuron,presumptive embryonic/larval central nervous system,presumptive embryonic/larval digestive system,external sensory organ precursor cell I,ventral nerve cord primordium" FBgn0001981 esg escargot http://flybase.org/reports/FBgn0001981 "FBgn0000445, FBgn0011711, FBgn0015967" protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay" "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype fusion cell fate specification ; GO:0035156 | traceable author statement negative regulation of DNA endoreduplication ; GO:0032876 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype cell fate determination ; GO:0001709 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement regulation of compound eye pigmentation ; GO:0048076 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | non-traceable author statement open tracheal system development ; GO:0007424 | traceable author statement asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with wor, sna gravitaxis ; GO:0042332 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay central nervous system development ; GO:0007417 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:P08044 maintenance of imaginal histoblast diploidy ; GO:0007489 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype genital disc development ; GO:0035215 | inferred from mutant phenotype response to nicotine ; GO:0035094 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay branch fusion, open tracheal system ; GO:0035147 | traceable author statement branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred by curator from GO:0003677 nucleus ; GO:0005634 | inferred from direct assay "esg, CG3758, BG:DS07851.7, l(2)35Ce, l(2)br43, wiz, l(2)esg, l35Ce, dgl, 4B7, br43, shof, l(2)4B7, l(2)07082, flg, Esg" IPR013087:Zinc finger C2H2-type CG3758 11-Aug-17 DroID_v2017_08 "Drer\prdm1a, Drer\snai1b, Drer\scrt1a, Drer\scrt1b, Drer\snai3, Drer\scrt2, Drer\znf410, Drer\snai1a, Drer\snai2" "Scer\YPR015C, Scer\AZF1" "Cele\klf-1, Cele\snai-1, Cele\M03D4.4, Cele\ztf-23, Cele\klu-1, Cele\ces-1" "Xtro\wt1, Xtro\snai2, Xtro\snai1, Xtro\znf410" "Mmus\Zfp410, Mmus\Snai1, Mmus\Scrt1, Mmus\Snai2, Mmus\Snai3, Mmus\Scrt2" "Hsap\ZNF683, Hsap\SCRT1, Hsap\SNAI3, Hsap\ZNF410, Hsap\SCRT2, Hsap\SNAI2, Hsap\ZNF710, Hsap\SNAI1" " larval stage | third instar , embryonic stage | stage 14 , embryonic stage | stage 14-16 , embryonic stage | stage 11 , embryonic stage | stage 16 , embryonic stage | stage 12 , embryonic stage && pupal stage , embryonic stage | stage 8-9 , embryonic stage " " central nervous system

, histoblast nest

, ventral midline

, dorsal mesothoracic disc | presumptive

, head

, ventral thoracic disc | presumptive

, dorsal metathoracic disc primordium

, embryonic/larval trachea

, ventral mesothoracic disc

, dorsal metathoracic disc

, histoblast

, dorsal ridge

, imaginal disc

, peripheral nervous system

, dorsal mesothoracic disc

, ventral neurogenic region

, ventral metathoracic disc

, genital disc

, ventral prothoracic disc

, ectoderm

" " embryonic stage | stage 13 , embryonic stage | stage 15 , embryonic stage | stage 5 " " tracheal fusion cell

, dorsal mesothoracic disc | presumptive

, ventral thoracic disc primordium | restricted & proximal

, dorsal mesothoracic disc

, dorsal metathoracic disc | presumptive

, embryonic/larval anterior spiracle

, genital disc | presumptive

, dorsal metathoracic disc

, ventral thoracic disc | presumptive

" "lethal,recessive,neurophysiology defective,female sterile,visible,dominant,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,smell perception defective,gravitaxis defective,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,somatic clone,heat sensitive,lethal - all die during pupal stage" "rhabdomere R7,embryonic/larval hemocyte | third instar larval stage,eye,macrochaeta & scutum-537.4,microchaeta & scutum-537.4,wing,chordotonal organ,lateral,imaginal disc,embryonic/larval tracheal system,ventral thoracic disc,somatic clone,embryonic/larval dorsal branch 1,embryonic/larval dorsal branch 2,embryonic/larval dorsal branch 3,embryonic/larval dorsal branch 4,embryonic/larval dorsal branch 5,embryonic/larval dorsal branch 6,embryonic/larval dorsal branch 7,embryonic/larval dorsal branch 8,embryonic/larval dorsal branch 9,embryonic/larval dorsal branch 10,embryonic/larval dorsal trunk,secondary pigment cell,tertiary pigment cell,histoblast,testis,macrochaeta,chaeta,adult thorax,thecogen cell,external sensory organ,tergite,sternite,lateral transverse muscle,muscle fiber,germinal proliferation center hub,hub cell,ommatidium,interommatidial bristle,scutellar bristle & trichogen cell455.2,scutellar bristle & tormogen cell455.2,tracheal system,leg,leg sensillum,leg & trichome | somatic clone,embryonic/larval salivary gland | embryonic stage,tracheal air sac,heat sensitive,dorsal air sac primordium tip cell,scutellar bristle,pigment cell,supernumerary" FBgn0259685 crb crumbs http://flybase.org/reports/FBgn0259685 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 spectrin binding ; GO:0030507 | traceable author statement protein kinase C binding ; GO:0005080 | inferred from physical interaction with aPKC" "morphogenesis of an epithelium=0002009 | traceable author statement <> establishment or maintenance of polarity of embryonic epithelium=0016332 |...<> zonula adherens assembly=0045186 | traceable author statement <> establishment of epithelial cell apical/basal polarity=0045198 | traceable author statement <> compound eye photoreceptor development=0042051 | traceable author statement <> cell morphogenesis involved in Malpighian tubule morphogenesis=0061336 |...<> salivary gland development=0007431 | traceable author statement <> zonula adherens assembly=0045186 |...<> rhabdomere development=0042052 |...<> amnioserosa maintenance=0046665 |...<> establishment or maintenance of epithelial cell apical/basal polarity=0045197 | traceable author statement <> dorsal closure, amnioserosa morphology change=0046664 |...<> cuticle development=0042335 |... genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 <> zonula adherens maintenance=0045218 |...<> photoreceptor cell maintenance=0045494 |...<> liquid clearance, open tracheal system=0035002 |... genetic interaction with crb <> adherens junction organization=0034332 |...<> negative regulation of Notch signaling pathway=0045746 |... genetic interaction with N <> rhabdomere morphogenesis=0061541 |...<> negative regulation of proteasomal ubiquitin-dependent protein catabolic process=0032435 |... genetic interaction with Prosβ6 <> nuclear chromosome segregation=0098813 |...<> open tracheal system development=0007424 |...<> establishment or maintenance of cell polarity=0007163 |...<> negative regulation of organ growth=0046621 |...<> oogenesis=0048477 |...<> regulation of imaginal disc growth=0045570 |...<> establishment or maintenance of apical/basal cell polarity=0035088 |...<> membrane organization=0061024 |...<> zonula adherens maintenance=0045218 | <> positive regulation of phosphorylation=0042327 |...<> morphogenesis of a polarized epithelium=0001738 | traceable author statement <> compound eye photoreceptor development=0042051 |...<> establishment or maintenance of polarity of follicular epithelium=0016334 |...<> salivary gland morphogenesis=0007435 |...<> protein localization=0008104 | traceable author statement <> protein stabilization=0050821 |...<> centrosome localization=0051642 |...<> nervous system development=0007399 |...<> compound eye morphogenesis=0001745 |...inferred from genetic interaction with ex inferred from genetic interaction with Mer inferred from genetic interaction with kibra <> membrane organization=0061024 | traceable author statement <> cell-cell junction assembly=0007043 | <> morphogenesis of an epithelium=0002009 | <> maintenance of apical/basal cell polarity=0035090 |...<> Malpighian tubule morphogenesis=0007443 |...<> positive regulation of cell proliferation=0008284 |...<> regulation of intracellular protein transport=0033157 |...<> regulation of hippo signaling=0035330 |... genetic interaction with ex inferred from genetic interaction with Mer inferred from genetic interaction with kibra <> regulation of protein localization=0032880 |...<> rhabdomere development=0042052 | <> dorsal closure=0007391 |...<> establishment or maintenance of cell polarity=0007163 | <> photoreceptor cell maintenance=0045494 | <> tube morphogenesis=0035239 |... mutant phenotype" apical plasma membrane ; GO:0016324 | non-traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay septate junction ; GO:0005918 | traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay apical plasma membrane ; GO:0016324 | traceable author statement rhabdomere ; GO:0016028 | inferred from direct assay integral component of membrane ; GO:0016021 | traceable author statement subapical complex ; GO:0035003 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity apicolateral plasma membrane ; GO:0016327 | inferred from direct assay inferred from physical interaction with sdt apicolateral plasma membrane ; GO:0016327 | inferred from direct assay "Crb, crb, far, Crumbs, Crbs, crumb, CT19912, CRB, l(3)j1B5, l(3)07207, 0509/20, 1384/04, l(3)S058104, CG6383, l(3)S050920, DmCrb, crumbs" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR009030:Growth factor receptor cysteine-rich domain" CG6383 11-Aug-17 DroID_v2017_08 "Drer\dpy19l1l, Drer\zgc:158328, Drer\svep1, Drer\adgrl4, Drer\si:ch73-173h19.3, Drer\scube1, Drer\adgrf6, Drer\col28a1a, Drer\gas6, Drer\crb2a, Drer\notch1b, Drer\dlb, Drer\fbn2b, Drer\efemp1, Drer\notch3, Drer\jag1a, Drer\crb1, Drer\jag1b, Drer\sned1, Drer\ltbp3, Drer\jag2a, Drer\LOC562634, Drer\fbln1, Drer\pros1, Drer\jag2b, Drer\notch1a, Drer\fbn2a, Drer\col28a1a, Drer\megf6b, Drer\notch2, Drer\crb2b, Drer\matn3a, Drer\si:ch211-69e5.1, Drer\LOC100535882, Drer\fbln7, Drer\scube3, Drer\LOC100332841" - "Cele\lin-12, Cele\glp-1, Cele\crb-1, Cele\mup-4, Cele\fbn-1, Cele\mua-3, Cele\slt-1" "Xtro\fbn1, Xtro\hgfac, Xtro\notch1, Xtro\matn4, Xtro\ltbp4, Xtro\svep1, Xtro\f12, Xtro\crb1, Xtro\jag1, Xtro\col14a1, Xtro\nell1, Xtro\crb2" "Mmus\Jag1, Mmus\Ltbp4, Mmus\Habp2, Mmus\Dlk2, Mmus\Hgfac, Mmus\Hmcn2, Mmus\Sned1, Mmus\Scube3, Mmus\Fbln7, Mmus\Fbn1, Mmus\Tdgf1, Mmus\Notch4, Mmus\Svep1, Mmus\Col22a1, Mmus\Crb1, Mmus\Fbn2, Mmus\Cfc1, Mmus\Vwde, Mmus\Egfl7, Mmus\Gas6, Mmus\Notch1, Mmus\Pros1, Mmus\Vwa1, Mmus\Cntnap2, Mmus\Jag2, Mmus\Ltbp1, Mmus\Dll4, Mmus\Notch3, Mmus\Matn3, Mmus\Col28a1, Mmus\Vwce, Mmus\Crb2, Mmus\Scube2, Mmus\Notch2, Mmus\Dll3, Mmus\F12, Mmus\Dlk1" "Hsap\SCUBE3, Hsap\F12, Hsap\SNED1, Hsap\EGFL7, Hsap\FBN1, Hsap\PROS1, Hsap\COL22A1, Hsap\LTBP1, Hsap\DLL3, Hsap\DLK2, Hsap\CRB1, Hsap\CRB2, Hsap\FBN3, Hsap\DLK1, Hsap\FBN2, Hsap\FBLN7, Hsap\VWCE, Hsap\CFC1B, Hsap\SVEP1, Hsap\VWA1, Hsap\CNTNAP2, Hsap\NOTCH1, Hsap\EYS, Hsap\MATN3, Hsap\NOTCH3, Hsap\GAS6, Hsap\NOTCH2, Hsap\TDGF1, Hsap\JAG2, Hsap\CFC1, Hsap\LOC100996717, Hsap\DLL4, Hsap\HGFAC, Hsap\HABP2, Hsap\JAG1, Hsap\NOTCH4, Hsap\SCUBE2, Hsap\NOTCH2NL, Hsap\COL14A1" " embryonic stage -- adult stage , embryonic stage | late , embryonic stage " " adult salivary gland primordium

posterior & dorsal , embryonic/larval hindgut

" " embryonic stage | late , larval stage | third instar , adult stage | male , embryonic stage , embryonic stage | stage 8-11 , pupal stage , embryonic stage | stage 16 , adult stage && oogenesis stage " " adult salivary gland primordium

, embryonic/larval garland cell

, ejaculatory bulb

, ectoderm

, optic lobe

, neuroblast

, photoreceptor cell stalk | apical

, hindgut

, embryonic/larval salivary gland

, external sensory organ

, embryonic/larval foregut

, ejaculatory duct

, embryonic peripheral nervous system

, testicular duct

, peripodial epithelium

, stomodeum

, salivary gland imaginal ring

, posterior embryonic/larval midgut

, embryonic/larval hindgut

, Malpighian tubule

, epithelial cell

, seminal vesicle

, follicle cell

, embryonic/larval trachea

, imaginal disc

, stomatogastric nervous system

, endoderm

, chordotonal organ

, male accessory gland

" FBgn0025185 az2 az2 http://flybase.org/reports/FBgn0025185 FBgn0022958 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with gl zinc ion binding ; GO:0008270 | inferred from sequence model" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with gl" cellular_component ; GO:0005575 | no biological data available "zf43C, CG1605, az2" "IPR006578:MADF domain, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1605 11-Aug-17 DroID_v2017_08 - - "Cele\mnm-2, Cele\eor-1, Cele\sdz-12" - "Mmus\Gm13212, Mmus\Zfp980, Mmus\Zfp995" "Hsap\ZNF585A, Hsap\ZNF133" " adult stage && oogenesis stage , adult stage | female && oogenesis stage | stage =S10B " " nurse cell

, ovary

, oocyte

" FBgn0262445 mir-133 mir-133 stem loop http://flybase.org/reports/FBgn0262445 miRNA_gene - - - "dme-miR-133, dme-mir-133, miR-133, mir-133, MIR-133, CR43011, CR33574" - CR43011 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage , pupal stage " "visible,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" "eye,wing,wing vein" FBgn0010389 htl heartless http://flybase.org/reports/FBgn0010389 "FBgn0004599, FBgn0022791" protein_coding_gene "fibroblast growth factor-activated receptor activity ; GO:0005007 | inferred from electronic annotation with InterPro:IPR016248 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR016248, InterPro:IPR017441 fibroblast growth factor-activated receptor activity ; GO:0005007 | traceable author statement protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:P11362" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR016248, InterPro:IPR020635 positive regulation of cell proliferation ; GO:0008284 | inferred from electronic annotation with InterPro:IPR016248 mesoderm migration involved in gastrulation ; GO:0007509 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype mesodermal cell fate determination ; GO:0007500 | inferred from expression pattern glial cell migration ; GO:0008347 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype lymph gland development ; GO:0048542 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from expression pattern central nervous system development ; GO:0007417 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype cell migration ; GO:0016477 | traceable author statement somatic muscle development ; GO:0007525 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype glial cell differentiation ; GO:0010001 | inferred from mutant phenotype gastrulation ; GO:0007369 | non-traceable author statement visceral muscle development ; GO:0007522 | inferred from mutant phenotype gonad development ; GO:0008406 | traceable author statement central nervous system development ; GO:0007417 | inferred from expression pattern gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | traceable author statement cardioblast differentiation ; GO:0010002 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement muscle fiber development ; GO:0048747 | inferred from mutant phenotype heart development ; GO:0007507 | non-traceable author statement pole cell migration ; GO:0007280 | traceable author statement heart development ; GO:0007507 | inferred from mutant phenotype mesodermal cell migration ; GO:0008078 | inferred from mutant phenotype mesodermal cell migration ; GO:0008078 | traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | inferred from sequence or structural similarity with UniProtKB:P11362 mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype mesodermal cell fate commitment ; GO:0001710 | inferred from mutant phenotype inferred from genetic interaction with dpp salivary gland development ; GO:0007431 | traceable author statement pericardial nephrocyte differentiation ; GO:0061320 | inferred from mutant phenotype mesodermal cell fate commitment ; GO:0001710 | inferred from mutant phenotype endodermal cell fate determination ; GO:0007493 | inferred from expression pattern protein phosphorylation ; GO:0006468 | non-traceable author statement" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR016248 "Htl, heartless, FGFR, CG7223, i79, i100, i150, j372, EMS2, DFR1, CT39172, CT22273, HTL/FGFR1, dtk1, DmHD-38, Dfr-1, DTRK(FR1), FGF-R2, DFGF-R1, FR1, DFR1/DFGF-R2, DFGF-R2, DFR-1, FGFR2, DPR3, Tk1, HD-38, Fr1, Dtk1, Dfr1, htl" "IPR000719:Protein kinase domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013783:Immunoglobulin-like fold, IPR016248:Fibroblast growth factor receptor family, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG7223 11-Aug-17 DroID_v2017_08 "Drer\fgfr1b, Drer\si:ch211-167j9.5, Drer\fgfrl1b, Drer\csf1ra, Drer\si:ch73-206d17.1, Drer\flt4, Drer\fgfr3, Drer\fgfrl1a, Drer\styk1, Drer\flt1, Drer\csf1rb, Drer\si:dkey-14o18.6, Drer\tie1, Drer\kita, Drer\pdgfrb, Drer\fgfr1a, Drer\ret, Drer\flt3, Drer\pdgfrl, Drer\pdgfra, Drer\fgfr4, Drer\kdr, Drer\LOC569566, Drer\tek, Drer\kdrl, Drer\fgfr2, Drer\kitb, Drer\tada2b" Scer\SKM1 "Cele\old-1, Cele\igcm-4, Cele\svh-2, Cele\F09A5.2, Cele\egl-15, Cele\kin-9, Cele\R151.1, Cele\C24G6.2, Cele\F09G2.1" "Xtro\flt1, Xtro\csf1r, Xtro\fgfr1, Xtro\styk1, Xtro\tek, Xtro\tie1, Xtro\ret, Xtro\tada2b, Xtro\fgfr3, Xtro\fgfr4, Xtro\pdgfra, Xtro\fgfr2, Xtro\fgfrl1, Xtro\pdgfrl.2, Xtro\kdr, Xtro\pdgfrl, Xtro\flt4" "Mmus\Flt4, Mmus\Fgfr1, Mmus\Flt1, Mmus\Fgfr4, Mmus\Fgfr2, Mmus\Pdgfrl, Mmus\Pdgfra, Mmus\Csf1r, Mmus\Ret, Mmus\Flt3, Mmus\Tie1, Mmus\Styk1, Mmus\Fgfrl1, Mmus\Pdgfrb, Mmus\Tada2b, Mmus\Tek, Mmus\Fgfr3, Mmus\Kdr, Mmus\Kit" "Hsap\TEK, Hsap\TIE1, Hsap\PDGFRL, Hsap\KIT, Hsap\FGFRL1, Hsap\TADA2B, Hsap\PDGFRA, Hsap\STYK1, Hsap\FGFR1, Hsap\FLT3, Hsap\FLT4, Hsap\FGFR2, Hsap\FLT1, Hsap\FGFR4, Hsap\RET, Hsap\CSF1R, Hsap\PDGFRB, Hsap\KDR, Hsap\FGFR3" " embryonic stage | stage 12-16 , embryonic stage | stage 12-13 , embryonic stage | stage 11-12 , embryonic stage | stage 13 , embryonic stage | stage 16 , embryonic stage | stage 9 , embryonic stage | stage 5-9 " " central nervous system

, embryonic/larval hindgut

, myoblast &&of larval muscle system

, abdominal 1--7 lateral transverse muscle 3

, abdominal 1--7 ventral acute muscle 2

, abdominal 1--7 ventral acute muscle 1

, longitudinal connective

, embryonic/larval foregut

, abdominal 1--7 lateral transverse muscle 2

, abdominal 2--7 ventral transverse muscle 1

, somatic mesoderm

, abdominal 1--7 lateral transverse muscle 1

, mesoderm

, head mesoderm

" " larval stage | third instar , embryonic stage | stage 11-12 " " dorsal mesothoracic disc && adepithelial cell | restricted

, mesoderm

" "lethal,recessive,wild-type,cell migration defective,increased cell death,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,increased cell number,viable,visible" "presumptive embryonic salivary gland,visceral mesoderm,muscle founder cell,myoblast,muscle fiber,glial cell,embryonic/larval dorsal vessel,embryonic visceral muscle,embryonic/larval somatic muscle,interface glial cell,hindgut visceral muscle primordium,hindgut visceral muscle fiber,mesoderm,embryonic/larval muscle system,dorsal,heart primordium,axon & ocellus sensory structureBx-MS1096, Mz1277, twi.PB, htlUAS.cMa,axon & mechanosensory neuron & adult headBx-MS1096, Mz1277, twi.PB, htlUAS.cMa,somatic mesoderm,axon & ocellus sensory structure-537.4, htlDN.UAS.cMb,axon & mechanosensory neuron & adult head-537.4, htlDN.UAS.cMb,cardiogenic mesoderm,lymph gland primordium,embryonic pericardial cell,cardioblast,pericardial cell,embryonic/larval pericardial cell,embryonic/larval cardial cell,ventral nerve cord,ventral furrow,somatic clone,corpus cardiacum primordium,longitudinal visceral muscle primordium,longitudinal visceral muscle fiber,dorsal oblique muscle,ventral longitudinal muscle,ventral oblique muscle,lateral transverse muscle,dorsal transverse muscle,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle 1,abdominal 1 dorsal acute muscle 1,abdominal 2 dorsal acute muscle 1,abdominal 3 dorsal acute muscle 1,abdominal 4 dorsal acute muscle 1,abdominal 5 dorsal acute muscle 1,abdominal 6 dorsal acute muscle 1,abdominal 7 dorsal acute muscle 1,embryonic myoblast,germline cell,gonadal sheath proper primordium,embryonic somatic muscle,axon & ocellus sensory structure-537.4,axon & mechanosensory neuron & adult head-537.4,axon & ocellus sensory structure-537.4, htlAB42,axon & mechanosensory neuron & adult head-537.4, htlAB42,subretinal glial cell,somatic clone | third instar larval stage,ventral nerve cord | embryonic stage,embryonic/larval dorsal vessel | embryonic stage,ventral,axon & ocellus sensory structureBx-MS1096, Mz1277, twi.PB, htlYY262/htlAB42,axon & mechanosensory neuron & adult headBx-MS1096, Mz1277, twi.PB, htlYY262/htlAB42,supernumerary,tarsal levator muscle,wing vein L5,wing vein,ectopic,embryonic cardioblast,trichogen cell" FBgn0266751 CR45224 - http://flybase.org/reports/FBgn0266751 non_protein_coding_gene - - - CR45224 - CR45224 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0016991 ms(2)1336A ms(2)1336A http://flybase.org/reports/FBgn0016991 - gene - - - "ms(3)1336A, ms(2)1336A" - - 11-Aug-17 DroID_v2017_08 - - - - - - spermatid FBgn0044400 Scim27 Sensitized chromosome inheritance modifier 27 http://flybase.org/reports/FBgn0044400 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim27 - - 11-Aug-17 DroID_v2017_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0004907 14-3-3zeta 14-3-3zeta http://flybase.org/reports/FBgn0004907 "FBgn0010635, FBgn0019723, FBgn0023038, FBgn0046306, FBgn0064146" protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from electronic annotation with InterPro:IPR000308 protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Slob protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with 14-3-3ε protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q45VV3 protein kinase C inhibitor activity ; GO:0008426 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A0A0B4K753 "thermosensory behavior ; GO:0040040 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from direct assay inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from genetic interaction with 14-3-3ε olfactory learning ; GO:0008355 | non-traceable author statement positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D protein stabilization ; GO:0050821 | inferred from direct assay inferred from mutant phenotype learning or memory ; GO:0007611 | non-traceable author statement germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with 14-3-3ε regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay germline ring canal ; GO:0045172 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "14-3-3zeta, leo, 14-3-3, PAR5, d14-3-3zeta, par-5, Par-5, CG17870, 4-3-3 zeta, D14-3-3zeta, 549, 2G1, 5.11, K, BEST:GH05075, l(2)07103, D14-3-3, l(2)46Ee, l(2)46CFe, 14-3-3ZETA, 14-3-3 zeta, Leo, PAR-5, 14-3-3leo, 14-3-3-zeta, LEO, 14-3-3-Leo" "IPR000308:14-3-3 protein, IPR023409:14-3-3 protein, conserved site, IPR023410:14-3-3 domain" CG17870 11-Aug-17 DroID_v2017_08 "Drer\ywhae1, Drer\ywhaqb, Drer\ywhabl, Drer\ywhabb, Drer\ywhae2, Drer\ywhaqa, Drer\ywhaz, Drer\ywhaba, Drer\ywhag1, Drer\ywhag2, Drer\ywhah" "Scer\BMH1, Scer\BMH2" "Cele\par-5, Cele\ftt-2" "Xtro\ywhah, Xtro\ywhag, Xtro\ywhaq, Xtro\ywhaz, Xtro\ywhab, Xtro\ywhae" "Mmus\Ywhag, Mmus\Ywhaz, Mmus\Cdk5rap2, Mmus\Ywhah, Mmus\Ywhae, Mmus\Sfn, Mmus\Ywhaq, Mmus\Ywhab" "Hsap\YWHAB, Hsap\SFN, Hsap\YWHAG, Hsap\YWHAH, Hsap\YWHAQ, Hsap\YWHAE, Hsap\YWHAZ" " adult stage , embryonic stage , larval stage | third instar , adult stage && oogenesis stage , larval stage " " retina

, adult brain

, ventral nerve cord

, lamina

, adult head

, subesophageal ganglion

, embryonic central nervous system

, optic lobe

, eye disc

, mushroom body

, nurse cell

, thoracico-abdominal ganglion

, oocyte

, antennal lobe

, morphogenetic furrow | posterior to

, larval central nervous system

" " adult stage && oogenesis stage , adult stage , larval stage | third instar , embryonic stage | 16-18hr , embryonic stage | late , embryonic stage | 20 hr , embryonic stage | stage 17 , larval stage " " oocyte

, thoracico-abdominal ganglion

, nurse cell

, ring neuron

, eye disc

, cell body

, synapse

, ellipsoid body

, bouton

, neuromuscular junction

, neuron

, larval muscle system

, morphogenetic furrow | posterior to

, mushroom body

, antennal lobe

" "memory defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,learning defective,neurophysiology defective,mitotic cell cycle defective,maternal effect,fertile,wild-type" "eye photoreceptor cell,somatic clone,embryonic/first instar larval cuticle,germline clone,denticle belt,syncytial blastoderm embryo,mitotic cell cycle | maternal effect,follicle cell,border follicle cell,photoreceptor cell,embryonic epidermis,lateral,dorsal,embryo,posterior,filzkorper" DRSC05028 I -2.132383757 -1.133882546 0.502046612 0.1426068 -0.137782331 -0.462856079 FBgn0259212 cno canoe http://flybase.org/reports/FBgn0259212 protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from physical interaction with pins protein binding ; GO:0005515 | inferred from physical interaction with Ran cell adhesion molecule binding ; GO:0050839 | inferred from biological aspect of ancestor with PANTHER:PTN001624603 Ras GTPase binding ; GO:0017016 | inferred from physical interaction with Rap1 "establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype inferred from genetic interaction with Ran inferred from genetic interaction with pins Ras protein signal transduction ; GO:0007265 | traceable author statement ommatidial rotation ; GO:0016318 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from genetic interaction with zip, PDZ-GEF second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype regulation of JNK cascade ; GO:0046328 | inferred from mutant phenotype inferred from genetic interaction with bsk embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype adherens junction organization ; GO:0034332 | inferred from biological aspect of ancestor with PANTHER:PTN001624603 compound eye development ; GO:0048749 | inferred from genetic interaction with mbt dorsal closure, elongation of leading edge cells ; GO:0007394 | non-traceable author statement glial cell proliferation ; GO:0014009 | inferred from mutant phenotype regulation of protein localization ; GO:0032880 | inferred from direct assay inferred from mutant phenotype epidermis morphogenesis ; GO:0048730 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from biological aspect of ancestor with PANTHER:PTN001624603 regulation of JNK cascade ; GO:0046328 | non-traceable author statement JNK cascade ; GO:0007254 | non-traceable author statement establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement Notch signaling pathway ; GO:0007219 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement" cell-cell junction ; GO:0005911 | inferred from electronic annotation with InterPro:IPR028842 adherens junction ; GO:0005912 | non-traceable author statement cell cortex ; GO:0005938 | inferred from direct assay zonula adherens ; GO:0005915 | traceable author statement adherens junction ; GO:0005912 | traceable author statement connecting hemi-adherens junction ; GO:0005926 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay "cno, EC3-10, CG42312, Cno, Canoe, lip, mis, dlhA, CG2534, anon-WO0172774.47, AF-6, CG31537, canoe, cno?" "IPR000159:Ras-associating (RA) domain, IPR000253:Forkhead-associated (FHA) domain, IPR001478:PDZ domain, IPR002710:Dilute domain, IPR008984:SMAD/FHA domain, IPR029071:Ubiquitin-related domain, IPR028842:Afadin" CG42312 11-Aug-17 DroID_v2017_08 "Drer\radil, Drer\rasip1, Drer\mllt4a" Scer\SEC3 Cele\afd-1 "Xtro\mllt4, Xtro\rasip1" "Mmus\Rasip1, Mmus\Afdn, Mmus\Radil" "Hsap\RASIP1, Hsap\AFDN, Hsap\RADIL" " embryonic stage -- adult stage , embryonic stage | stage 5 , embryonic stage | stage 10 , embryonic stage | stage 13 , embryonic stage | stage 7-10 , embryonic stage , larval stage " " organism | restricted

,

ubiquitous , ectoderm

, embryonic/larval proventriculus

, posterior embryonic/larval midgut

, epidermis

, organism | striped

, eye-antennal disc

" FBgn0004860 ph-d polyhomeotic distal http://flybase.org/reports/FBgn0004860 "FBgn0003077, FBgn0026824" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012313 chromatin binding ; GO:0003682 | inferred from direct assay chaperone binding ; GO:0051087 | inferred from direct assay core promoter binding ; GO:0001047 | inferred from direct assay "syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | non-traceable author statement" PRC1 complex ; GO:0035102 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay PRC1 complex ; GO:0035102 | traceable author statement nucleolus ; GO:0005730 | inferred from direct assay chromatin ; GO:0000785 | non-traceable author statement "Ph, PH, ph, CG3895, PH-d, EG:BACN25G24.3, DROZFP, phd, ph[D], ph-D, phm, ph-d, PHD, Ph-d, ph[d], PhD" "IPR001660:Sterile alpha motif domain, IPR012313:Zinc finger, FCS-type, IPR013761:Sterile alpha motif/pointed domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001715:Calponin homology domain" CG3895 11-Aug-17 DroID_v2017_08 "Drer\sfmbt1, Drer\phc2b, Drer\samd7, Drer\phc1, Drer\phc2a, Drer\si:ch211-230g15.5, Drer\phc3, Drer\samd11, Drer\sfmbt2, Drer\scml4" - "Cele\sor-3, Cele\K02F6.7" "Xtro\phc2, Xtro\phc3" "Mmus\Samd11, Mmus\Sfmbt2, Mmus\Sfmbt1, Mmus\Samd7, Mmus\Phc3, Mmus\Scml4, Mmus\Phc1, Mmus\Phc2" "Hsap\SCML4, Hsap\PHC3, Hsap\SAMD7, Hsap\SAMD11, Hsap\SFMBT1, Hsap\SCML1, Hsap\PHC1, Hsap\SFMBT2, Hsap\PHC2" " adult stage && oogenesis stage | stage S1-10 , larval stage | third instar , embryonic stage | blastoderm , embryonic stage | stage >=12 , embryonic stage | stage 8-11 , embryonic stage , adult stage && oogenesis stage , embryonic stage -- adult stage " " follicle cell

, ventral thoracic disc

, nurse cell

,

50-80% egg length , embryonic central nervous system

, eye-antennal disc

, germ band

, parasegment | restricted

, dorsal mesothoracic disc

, germarium

, dorsal metathoracic disc

,

ubiquitous " " embryonic stage , larval stage | third instar , embryonic stage | late " " cell body

,

ubiquitous , dorsal mesothoracic disc

, embryonic peripheral nervous system

, ventral thoracic disc

, dorsal metathoracic disc

, sensillum campaniformium

, embryonic central nervous system

, eye-antennal disc

" "viable,wild-type,lethal,recessive,heat sensitive,visible,eye color defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "mesothoracic leg,metathoracic leg,wing,posterior compartment,abdominal segment 1,abdominal segment 4,humerus,humeral bristle,anterior compartment,heat sensitive,adult abdominal segment 1,adult abdominal segment 4,sex comb,eye,wing margin bristle,abdominal sternite 6,female,abdominal sternite 7,genitalia,adult thoracic segment,adult abdominal segment,cuticle,head,nuclear chromosome,ventral,cuticle & denticle,epidermis,cell autonomous,somatic clone" DRSC23191 K 1.910230444 1.155417935 FBgn0003249 Rh3 Rhodopsin 3 http://flybase.org/reports/FBgn0003249 - protein_coding_gene G-protein coupled photoreceptor activity ; GO:0008020 | traceable author statement G-protein coupled photoreceptor activity ; GO:0008020 | non-traceable author statement G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity G-protein coupled photoreceptor activity ; GO:0008020 | inferred from direct assay G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with ninaE "visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR000856 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000856 phototransduction, UV ; GO:0007604 | traceable author statement absorption of UV light ; GO:0016039 | inferred from mutant phenotype phototransduction, UV ; GO:0007604 | non-traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity detection of UV ; GO:0009589 | traceable author statement phototransduction, UV ; GO:0007604 | inferred from direct assay phototransduction ; GO:0007602 | non-traceable author statement" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000856, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "Rh3, rh3, Rh, FBgn0003249, DMELRH3, Dm Rh3, RH3, CG10888" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000856:Opsin RH3/RH4, IPR017452:GPCR, rhodopsin-like, 7TM, IPR027430:Visual pigments (opsins) retinal binding site" CG10888 11-Aug-17 DroID_v2017_08 "Drer\opn8c, Drer\opn4xb, Drer\parapinopsinb, Drer\rgra, Drer\rhol, Drer\opn4a, Drer\valopa, Drer\opn1lw1, Drer\parietopsin, Drer\opn4xa, Drer\opn1mw1, Drer\tmtops3a, Drer\opn4.1, Drer\opn6b, Drer\opn7d, Drer\opn7b, Drer\rrh, Drer\opn1sw1, Drer\tmtops3b, Drer\opn1mw4, Drer\opn8b, Drer\rho, Drer\opn5, Drer\valopb, Drer\opn7c, Drer\opn1lw2, Drer\tmtops2b, Drer\tmtopsb, Drer\opn1sw2, Drer\opn6a, Drer\tmtops2a, Drer\rgrb, Drer\opn4b, Drer\opn9, Drer\exorh, Drer\opn3, Drer\opn7a, Drer\opn1mw3" - "Cele\nmur-3, Cele\sro-1" "Xtro\tmtops, Xtro\LOC100485989, Xtro\rho, Xtro\opn1lw, Xtro\opn5, Xtro\tmtops.2, Xtro\LOC100485437, Xtro\rrh, Xtro\opn1sw, Xtro\LOC100124934" "Mmus\Rho, Mmus\Opn3, Mmus\Rrh, Mmus\Opn1sw, Mmus\Opn4, Mmus\Opn5, Mmus\Rgr, Mmus\Opn1mw" "Hsap\OPN4, Hsap\OPN5, Hsap\RHO, Hsap\OPN1MW, Hsap\OPN1LW, Hsap\OPN1MW2, Hsap\OPN3, Hsap\OPN1MW3, Hsap\RGR, Hsap\OPN1SW, Hsap\RRH" " larval stage , adult stage , pupal stage | late " " Bolwig's organ

, eye

, photoreceptor cell R7

, adult head

" adult stage " photoreceptor cell R1--6

{ 0 ninaE- } , photoreceptor cell R1..6

{ 0 ninaA* } , photoreceptor cell R1--6

, photoreceptor cell R8

, photoreceptor cell R7 | presumptive

" "neurophysiology defective,visual behavior defective,viable" "ommatidium,eye photoreceptor cell" FBgn0013811 Dhc62B Dynein heavy chain at 62B http://flybase.org/reports/FBgn0013811 FBgn0035269 protein_coding_gene "ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" retrograde axonal transport ; GO:0008090 | inferred from mutant phenotype cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity inner dynein arm ; GO:0036156 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 "dhc, DHC, Dhc, CG18613, CG15804, Dhc62B, DHC7C" "IPR004273:Dynein heavy chain domain, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain" CG15804 11-Aug-17 DroID_v2017_08 "Drer\dnah12, Drer\dnah7l, Drer\dnah9l, Drer\dnah2, Drer\si:dkeyp-87a6.1, Drer\si:dkeyp-86b9.1, Drer\dnah7, Drer\wu:fj30b09, Drer\dnah1, Drer\dnah3, Drer\dync1h1" Scer\DYN1 - "Xtro\dnah2, Xtro\dnah12, Xtro\dnah7, Xtro\dnah14" "Mmus\Dnah9, Mmus\Dnah17, Mmus\Dnah6, Mmus\Dnah5, Mmus\Dnah8, Mmus\Dnah10, Mmus\Dnah2, Mmus\Dnah7c, Mmus\Dnah12, Mmus\Dnah1, Mmus\Dnah3, Mmus\Dync1h1, Mmus\Dnah11, Mmus\Dnah7b, Mmus\Dnhd1, Mmus\Dync2h1, Mmus\Dnah7a" "Hsap\DNAH3, Hsap\DYNC1H1, Hsap\DNAH1, Hsap\CCDC88B, Hsap\DNAH10, Hsap\DNAH12, Hsap\DNAH2, Hsap\DNAH9, Hsap\DNAH8, Hsap\DNAH6, Hsap\DNAH7, Hsap\DNAH17, Hsap\DNAH11, Hsap\DNHD1, Hsap\DNAH5, Hsap\DYNC2H1" " adult stage , adult stage | male , embryonic stage , adult stage | female " testis

"viable,fertile,lethal" FBgn0004580 Cbp53E Calbindin 53E http://flybase.org/reports/FBgn0004580 - protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium ion binding ; GO:0005509 | traceable author statement regulation of cytosolic calcium ion concentration ; GO:0051480 | inferred from biological aspect of ancestor with PANTHER:PTN001461922 negative regulation of response to wounding ; GO:1903035 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001461922 type II terminal bouton ; GO:0061175 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001461922 type III terminal bouton ; GO:0097467 | inferred from direct assay "cbn, cbp53E, Dcp, DCBP, Dcbp, CG6702, Cbp53E, Calb, Cbp33, CALB2/calretinin, CALB2" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG6702 11-Aug-17 DroID_v2017_08 "Drer\calb2a, Drer\rhbdl3, Drer\pvalb2, Drer\cabp7b, Drer\pvalb4, Drer\calb2b, Drer\pvalb8, Drer\cabp2a, Drer\cabp5a, Drer\efcab6, Drer\calm2a, Drer\tnnc1a, Drer\pvalb6, Drer\calm1a, Drer\scgn, Drer\tnnc1b, Drer\tnnc2, Drer\calm1b, Drer\calm3a, Drer\calm2b, Drer\caln2, Drer\efcab11, Drer\pvalb1, Drer\caln1, Drer\cabp5b, Drer\efcab2, Drer\calb1, Drer\calm3b, Drer\calml4b, Drer\pvalb3, Drer\calml4a, Drer\pvalb9, Drer\si:ch211-197n1.2, Drer\cabp1a" "Scer\CMD1, Scer\MLC2, Scer\MLC1" "Cele\pat-10, Cele\tnc-2" "Xtro\pvalb.1, Xtro\pvalb.2, Xtro\cabp7, Xtro\pvalb, Xtro\LOC548651, Xtro\ocm, Xtro\calm1, Xtro\calb1, Xtro\cabp4, Xtro\pgm1, Xtro\ocm.2, Xtro\scgn, Xtro\calm2, Xtro\calml4, Xtro\tnnc2, Xtro\efcab6, Xtro\tnnc1" "Mmus\Cabp1, Mmus\Rhbdl3, Mmus\Efcab11, Mmus\Calm2, Mmus\Efcab6, Mmus\Efcab9, Mmus\Calm1, Mmus\Calb1, Mmus\Efcab2, Mmus\Caln1, Mmus\1700023F06Rik, Mmus\Calml3, Mmus\Efcab3, Mmus\Calml4, Mmus\Tnnc2, Mmus\Spata21, Mmus\Scgn, Mmus\Cabp4, Mmus\Tnnc1, Mmus\Cabp2, Mmus\Pvalb, Mmus\Cabp7, Mmus\Ocm, Mmus\Calb2, Mmus\Cabp5, Mmus\Calm3, Mmus\Calm4, Mmus\Efcab7" "Hsap\CALM1, Hsap\CALML6, Hsap\CALB2, Hsap\EFCAB3, Hsap\SPATA21, Hsap\EFCAB13, Hsap\EFCAB9, Hsap\TNNC2, Hsap\CALB1, Hsap\CABP2, Hsap\EFCAB7, Hsap\CALML3, Hsap\PVALB, Hsap\EFCAB11, Hsap\RHBDL3, Hsap\CALML4, Hsap\CABP4, Hsap\CABP5, Hsap\CALN1, Hsap\OCM2, Hsap\TNNC1, Hsap\CABP1, Hsap\CALM3, Hsap\CALM2, Hsap\EFCAB2, Hsap\CALML5, Hsap\EFCAB6, Hsap\OCM, Hsap\SCGN, Hsap\CABP7" " adult stage , larval stage | third instar , embryonic stage | >12hr , embryonic stage | late " " ocellar nerve

, medulla layer M2

, antenna | restricted

, larval central nervous system | restricted

, adult central nervous system

, neuron

, embryonic central nervous system | restricted

, embryonic peripheral nervous system | restricted

, lamina

, thoracico-abdominal ganglion

, direct flight muscle

, ventral midline

, adult brain | restricted

" " embryonic stage | >12hr , adult stage , embryonic stage | > 12hr , larval stage | third instar , embryonic stage | late " " embryonic peripheral nervous system | restricted

, lamina

, embryonic central nervous system | restricted

, neuron

, larval central nervous system | restricted

, ventral midline

, adult brain | restricted

, adult central nervous system

, antenna

, thoracico-abdominal ganglion

, direct flight muscle

, medulla layer M2

" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0004837 Su(H) Suppressor of Hairless http://flybase.org/reports/FBgn0004837 "FBgn0003566, FBgn0004467, FBgn0021969, FBgn0022068, FBgn0063792" protein_coding_gene "RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from electronic annotation with InterPro:IPR015350 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | contributes_to inferred from genetic interaction with ebi RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with ebi inferred from physical interaction with Smr sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with N DNA binding ; GO:0003677 | non-traceable author statement transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from mutant phenotype" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | NOT non-traceable author statement positive regulation of G1/S transition of mitotic cell cycle ; GO:1900087 | inferred from mutant phenotype crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Psn hemopoiesis ; GO:0030097 | traceable author statement imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from genetic interaction with Sox15 Notch signaling pathway ; GO:0007219 | non-traceable author statement long-term memory ; GO:0007616 | inferred from mutant phenotype I-kappaB phosphorylation ; GO:0007252 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | traceable author statement cell fate determination ; GO:0001709 | traceable author statement Notch signaling pathway ; GO:0007219 | traceable author statement sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N negative regulation of compound eye cone cell fate specification ; GO:0042683 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement lateral inhibition ; GO:0046331 | traceable author statement" nucleus ; GO:0005634 | traceable author statement protein complex ; GO:0043234 | inferred from physical interaction with N nucleus ; GO:0005634 | inferred from direct assay transcriptional repressor complex ; GO:0017053 | inferred from genetic interaction with ebi cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity polytene chromosome ; GO:0005700 | inferred from direct assay "Su(H), SU(H), SuH, Su(h), FTZ-F2, oss, dRBP-JK, l(2)br7, dRBP-Jk, BG:DS00929.10, l(2)35Bh, su(H), l(2)k07904, RBP-J[[Kappa]], br7, C, dRBP-J[[Kappa]], l(1)br7, RBP-Jkappa, E(H), anon-WO0257455.3, D, CG3497, RBP-J kappa, CBF1, SUH, CSL, RBJK_DROME, Su_H" "IPR008967:p53-like transcription factor, DNA-binding, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR015350:Beta-trefoil DNA-binding domain, IPR015351:LAG1, DNA binding" CG3497 11-Aug-17 DroID_v2017_08 "Drer\rbpjb, Drer\rbpja, Drer\rbpjl" - Cele\lag-1 Xtro\rbpj "Mmus\Rbpj, Mmus\Rbpjl" "Hsap\RBPJ, Hsap\RBPJL" " embryonic stage | early , adult stage | female , adult stage | male , pupal stage | 24hr , embryonic stage , embryonic stage | stage >=11 , embryonic stage -- adult stage , larval stage | third instar , pupal stage | 16-24 hr , pupal stage | 16-24hr " " tormogen cell

, external sensory organ

, trichogen cell

, eye-antennal disc

, epidermis

, ventral thoracic disc

, dorsal mesothoracic disc

, adult muscle system | presumptive

" " larval stage | third instar , pupal stage , embryonic stage " " proneural cluster

, socket

, external sensory organ precursor cell IIb

, external sensory organ

, dorsal mesothoracic disc

, external sensory organ precursor cell IIa

, socket &&of interommatidial bristle

, embryonic peripheral nervous system | restricted

, sensory mother cell

" "hyperplasia,visible,neuroanatomy defective,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,neurogenic phenotype,rescuable maternal effect,somatic clone,wild-type,memory defective,increased cell death,mitotic cell cycle defective,cell autonomous,dominant,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" "wing,wing margin,wing disc | third instar larval stage,macrochaeta,microchaeta,eye,apterous-expressing neuron of the lateral cluster of the thorax,chaeta,adult thorax,imaginal disc,wing vein,trichogen cell,ommatidium,wing disc,proneural cluster,proventriculus inner layer primordium,proventriculus intermediate layer primordium,proventriculus outer layer primordium,embryonic proventriculus,keyhole structure,embryonic/first instar larval cuticle,germline clone,ventral,embryonic/first instar larval cuticle & embryonic head | germ-line clone,neuroblast,central nervous system,peripheral nervous system,sensory mother cell,ectopic,dorsal double row,ventral double row,proneural cluster & dorsal mesothoracic disc,wing vein L3,femur,distal,somatic clone,tibia,proximal,joint,leg,anterior compartment,eye-antennal disc,socket,tormogen cell,crystal cell,embryonic/larval lymph gland,haltere,dorsal mesothoracic disc & neuron,eye disc,follicle cell,egg chamber,germinal vesicle | somatic clone,photoreceptor cell R8 & eye disc | somatic clone,photoreceptor cell R8 & eye disc | ectopic | somatic clone,neuron & eye | supernumerary | somatic clone,neuron & eye | somatic clone,adult midgut,germarium region 1,cell autonomous,larval outer optic anlage,intestinal stem cell,supernumerary,type II neuroblast,adult midgut epithelium,mesothoracic tergum & sensory organ cell & pupa | somatic clone,sensory organ cell,unguis,plasmatocyte,eye disc & neuron | somatic clone | cell autonomous,photoreceptor cell R8,neuron,dMP2 neuron,vMP2 neuron,RP2sib neuron,RP2 motor neuron,Usib neuron,U neuron,embryonic/larval somatic muscle,embryonic epidermis,photoreceptor cell & axon & larva,photoreceptor cell,macrochaeta & leg,macrochaeta & adult abdomen,mesothoracic tergum,medial,anterior crossvein,wing margin bristle,visceral mesoderm,midline glial cell,medulla,pericardial cell,A1-7 dorsal acute muscle 1,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle 1,embryonic hindgut,embryonic large intestine,follicle stem cell,dorsal cluster neuron" FBgn0004895 FoxL1 Forkhead box L1 http://flybase.org/reports/FBgn0004895 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "Dmfd2, FD2, fd2, CG1132, FoxL1, fd64A, Fd64A, foxL1" "IPR018122:Fork head domain conserved site1, IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG1132 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-262e15.1, Drer\foxb1b, Drer\foxj1a, Drer\foxg1a, Drer\foxa3, Drer\foxe3, Drer\foxd5, Drer\foxa, Drer\foxa2, Drer\foxl1, Drer\foxc1a, Drer\foxd2, Drer\foxd3, Drer\zgc:162612, Drer\si:dkey-7e14.3, Drer\foxb1a, Drer\foxk1, Drer\foxb2, Drer\foxa1, Drer\zgc:194189, Drer\foxi3b, Drer\foxi1, Drer\LOC100149117, Drer\foxq2, Drer\foxl2, Drer\foxi3a, Drer\foxd1, Drer\foxe1, Drer\foxc1b, Drer\foxi2, Drer\foxk2" "Scer\FKH2, Scer\HCM1, Scer\FKH1" "Cele\unc-130, Cele\pha-4, Cele\fkh-10, Cele\lin-31, Cele\fkh-6, Cele\fkh-3, Cele\fkh-5, Cele\fkh-4, Cele\fkh-2" "Xtro\foxi4.1, Xtro\foxi1, Xtro\foxi4.2, Xtro\foxk2, Xtro\foxa2, Xtro\foxe3, Xtro\foxd2, Xtro\foxi2, Xtro\foxc1, Xtro\foxl2, Xtro\foxd3, Xtro\foxj1, Xtro\foxd1, Xtro\foxl1, Xtro\foxa4, Xtro\foxe1, Xtro\foxd4l1.1, Xtro\foxj1.2, Xtro\foxb1, Xtro\foxa1, Xtro\foxc2" "Mmus\Foxd3, Mmus\Foxa3, Mmus\Foxb2, Mmus\Foxk2, Mmus\Foxi3, Mmus\Foxd4, Mmus\Foxl1, Mmus\Foxj1, Mmus\Foxc1, Mmus\Foxc2, Mmus\Foxa1, Mmus\Foxa2, Mmus\Foxd2, Mmus\Foxb1, Mmus\Foxi2, Mmus\Gm5294, Mmus\Foxi1, Mmus\Foxl2, Mmus\Foxk1, Mmus\Foxd1, Mmus\Foxs1, Mmus\Foxe1, Mmus\Foxg1" "Hsap\FOXS1, Hsap\FOXL2, Hsap\FOXC2, Hsap\FOXJ1, Hsap\FOXD2, Hsap\FOXC1, Hsap\FOXB2, Hsap\FOXL1, Hsap\FOXA3, Hsap\FOXD4L5, Hsap\FOXI1, Hsap\FOXD1, Hsap\FOXD4L6, Hsap\FOXD4L1, Hsap\FOXD4L3, Hsap\FOXI2, Hsap\FOXA1, Hsap\FOXG1, Hsap\FOXD3, Hsap\FOXD4L4, Hsap\FOXB1, Hsap\FOXD4, Hsap\FOXA2, Hsap\FOXK2, Hsap\FOXE1, Hsap\FOXK1, Hsap\FOXI3" " embryonic stage | cellular blastoderm , embryonic stage " mesoderm

viable DRSC08717 E 0.973917967 -0.805484497 1.792386806 0.153550027 -0.768781966 0.555887593 FBgn0010194 Wnt5 Wnt oncogene analog 5 http://flybase.org/reports/FBgn0010194 "FBgn0004361, FBgn0066822" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VWV9 receptor binding ; GO:0005102 | inferred from physical interaction with drl frizzled binding ; GO:0005109 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 receptor binding ; GO:0005102 | inferred from sequence or structural similarity with wg salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype chemorepulsion of axon ; GO:0061643 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype inferred from genetic interaction with drl Wnt signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with wg determination of muscle attachment site ; GO:0016204 | inferred from mutant phenotype negative chemotaxis ; GO:0050919 | inferred from mutant phenotype positive regulation of axon extension ; GO:0045773 | inferred from genetic interaction with DAAM positive regulation of axon guidance ; GO:1902669 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 axon extension ; GO:0048675 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with uzip Wnt signaling pathway ; GO:0016055 | inferred from genetic interaction with drl dendrite ; GO:0030425 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity with wg extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000246517 extracellular region ; GO:0005576 | inferred from direct assay "wnt5, DWnt5, DWnt3, Dwnt5, DWnt-3/5, Wnt3/5, DWnt-5, Wnt-3, DWnt-3, Dwnt-5, Wnt, Dwnt-3, Wnt3, Dm-3, wnt3, CG6407, anon-WO03040301.228, Wnt5, DWnt3/5, Dm DWnt3/5, WNT5, Dwnt3" "IPR018161:Wnt protein, conserved site, IPR005817:Wnt" CG6407 11-Aug-17 DroID_v2017_08 "Drer\wnt11r, Drer\wnt8b, Drer\wnt8-2, Drer\wnt4a, Drer\wnt6b, Drer\wnt7ba, Drer\wnt11, Drer\wnt10a, Drer\wnt5b, Drer\wnt9b, Drer\wnt1, Drer\wnt2bb, Drer\wnt3a, Drer\wnt7bb, Drer\wnt7aa, Drer\wnt8a, Drer\wnt3, Drer\wnt9a, Drer\wnt4b, Drer\wnt16, Drer\wnt6a, Drer\wnt2ba, Drer\LOC568110, Drer\wnt5a, Drer\wnt2, Drer\wnt10b" - "Cele\egl-20, Cele\mom-2, Cele\cwn-2, Cele\cwn-1" "Xtro\wnt9b, Xtro\wnt7c, Xtro\wnt11r, Xtro\wnt1, Xtro\wnt9b.2, Xtro\wnt4, Xtro\wnt7b, Xtro\wnt3a, Xtro\wnt7a, Xtro\wnt8b, Xtro\wnt2b, Xtro\wnt16, Xtro\wnt11, Xtro\wnt10b, Xtro\wnt5b, Xtro\wnt8a" "Mmus\Wnt11, Mmus\Wnt5b, Mmus\Wnt8b, Mmus\Wnt2b, Mmus\Wnt10a, Mmus\Wnt6, Mmus\Wnt3a, Mmus\Wnt2, Mmus\Wnt1, Mmus\Wnt5a, Mmus\Wnt16, Mmus\Wnt9b, Mmus\Wnt9a, Mmus\Wnt10b, Mmus\Wnt7a, Mmus\Wnt3, Mmus\Wnt4, Mmus\Wnt7b, Mmus\Wnt8a" "Hsap\WNT1, Hsap\WNT10A, Hsap\WNT3, Hsap\WNT6, Hsap\WNT5B, Hsap\WNT8A, Hsap\WNT2B, Hsap\WNT2, Hsap\WNT11, Hsap\WNT7B, Hsap\WNT7A, Hsap\WNT8B, Hsap\WNT3A, Hsap\WNT9A, Hsap\WNT16, Hsap\WNT9B, Hsap\WNT4, Hsap\WNT5A, Hsap\WNT10B" " embryonic stage | stage 10-11 , embryonic stage | stage 9-11 , embryonic stage | stage 11 , embryonic stage | gastrula , embryonic stage | stage 14-16 , embryonic stage , embryonic stage | cellular blastoderm , embryonic stage -- adult stage , embryonic stage | stage >11 , embryonic stage | stage 6-15 " " antennal segment

, antennal lobe

{ - Ba* } , maxillary lobe

, ventral metathoracic disc primordium

, ventral furrow | presumptive

, labral segment

{ - Ba* } , embryonic central nervous system

, ventral nerve cord

, ventral mesothoracic disc primordium

, antennal lobe

, ventral thoracic disc

,

20-80% egg length , ventral prothoracic disc primordium

, labial segment

, neuron &&of embryonic central nervous system | primordium

, maxillary lobe

{ - Ba* } , ventral neurectoderm

{ - Ba* } , embryonic brain

, mesoderm

, labial segment

{ - Ba* } , labral segment

" " embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage | stage 12 , embryonic stage | stage 13 " " labial segment

, ventral thoracic disc primordium

, labral segment

, embryonic brain

, maxillary segment

, neuromere

, antennal segment

, ventral nerve cord

segmentally repeated " "viable,fertile,uncoordinated,neuroanatomy defective,lethal,partially,recessive,visible,partially lethal - majority die,some die during pupal stage" "anterior commissure,presumptive embryonic salivary gland,antennal lobe,glomerulus,commissure,lateral longitudinal fascicle,intermediate longitudinal fascicle,axon & dorsal cluster neuron,fascicle,presumptive embryonic/larval central nervous system,MP1 neuron,MP1 tract,vMP2 tract,lateral transverse muscle,ventral nerve cord,trichogen cell,mesothoracic tergum" FBgn0261954 east enhanced adult sensory threshold http://flybase.org/reports/FBgn0261954 protein_coding_gene - negative regulation of gene expression ; GO:0010629 | inferred from expression pattern inferred from genetic interaction with w metamorphosis ; GO:0007552 | inferred from mutant phenotype achiasmate meiosis I ; GO:0000705 | inferred from mutant phenotype regulation of metaphase plate congression ; GO:0090235 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay nuclear chromosome ; GO:0000228 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleolus ; GO:0005730 | NOT inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "east, su(w[sp]), l(1)G0500, EG:133E12.4, CG4399, l(1)G0014, anon-WO03040301.224, EAST, East" - CG4399 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | third instar , embryonic stage , embryonic stage | stage 9-17 , embryonic stage | stage 10 " " morphogenetic furrow

, procephalic neurogenic region

, embryonic central nervous system | presumptive

, peripheral nervous system

, supraesophageal ganglion

, sense organ

, eye-antennal disc

, tracheal primordium

, ventral neurogenic region

" DRSC18770 IE -0.646637796 -3.224435343 -1.200404052 -2.450070507 -0.73851466 -1.205191997 FBgn0005597 yemG9.5 yema gene 9.5 http://flybase.org/reports/FBgn0005597 FBgn0004042 gene - - - "yG9.5, yT9.5, yemG9.5" - - 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | early , larval stage | second instar , larval stage | third instar , larval stage--adult stage , larval stage | first instar , adult stage && oogenesis stage , embryonic stage | stage >=11 , embryonic stage | stage >=15 , pupal stage--adult stage , adult stage , embryonic stage -- adult stage , pupal stage " " neuroblast

, spermatocyte

, ganglion mother cell

, ovary

, embryonic brain

,

ubiquitous , nurse cell

, embryonic central nervous system | subset

, adult brain cortex

, optic lobe

, imaginal disc

, neuroblast | ventral

" FBgn0013342 nSyb neuronal Synaptobrevin http://flybase.org/reports/FBgn0013342 - protein_coding_gene "SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNAP receptor activity ; GO:0005484 | inferred from direct assay SNARE binding ; GO:0000149 | inferred from physical interaction with Snap25, Syx1A SNAP receptor activity ; GO:0005484 | non-traceable author statement" exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity vesicle-mediated transport ; GO:0016192 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle fusion ; GO:0006906 | inferred from direct assay synaptic vesicle docking ; GO:0016081 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001388 synaptic vesicle ; GO:0008021 | colocalizes_with inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay SNARE complex ; GO:0031201 | inferred from direct assay synaptic vesicle ; GO:0008021 | non-traceable author statement plasma membrane ; GO:0005886 | non-traceable author statement synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity presynaptic active zone ; GO:0048786 | colocalizes_with inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay "n-Syb, Nsyb, syb, CG17248, nSYB, nsyb, SYB, Dn-syb, Syb62A, n-syb, Syb, N-syb, nSyb, N-Syb, N-SYB, NSYB" IPR001388:Synaptobrevin CG17248 11-Aug-17 DroID_v2017_08 "Drer\sec22bb, Drer\sec22ba, Drer\sec22a, Drer\vamp3, Drer\vamp2, Drer\vamp8, Drer\zgc:92912, Drer\sec22c, Drer\vamp1, Drer\sybl1, Drer\vamp5" "Scer\NYV1, Scer\SNC2, Scer\SNC1" "Cele\snb-7, Cele\snb-1, Cele\vamp-7, Cele\snb-2, Cele\vamp-8, Cele\snb-5, Cele\snb-6, Cele\sec-22" "Xtro\vamp3, Xtro\vamp7, Xtro\vamp4, Xtro\sec22b, Xtro\sec22a, Xtro\vamp1, Xtro\sec22c, Xtro\ykt6, Xtro\vamp2" "Mmus\Sec22b, Mmus\Sec22a, Mmus\Vamp2, Mmus\Ykt6, Mmus\Vamp7, Mmus\Vamp5, Mmus\Vamp4, Mmus\Vamp1, Mmus\Sec22c, Mmus\Vamp3, Mmus\Vamp8" "Hsap\VAMP2, Hsap\VAMP8, Hsap\VAMP3, Hsap\VAMP4, Hsap\VAMP5, Hsap\VAMP1, Hsap\SEC22C, Hsap\SEC22B, Hsap\YKT6, Hsap\VAMP7" " embryonic stage -- adult stage , adult stage , embryonic stage | stage >=13 " " photoreceptor cell

, thoracico-abdominal ganglion

, embryonic peripheral nervous system

, adult brain cortex

, embryonic central nervous system

, cell body &&of optic lobe

" " embryonic stage , larval stage " " ventral nerve cord

, segmental nerve

, bouton

, synapse

, synapse &&of neuromuscular junction

, neuromuscular junction

, intersegmental nerve

, ventral nerve cord commissure

, neuromuscular junction &&of abdominal 1 ventral longitudinal muscle 4

, neuromuscular junction &&of abdominal 1 ventral longitudinal muscle 3

" "uncoordinated,viable,hypoactive,recessive,neurophysiology defective,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,behavior defective" "synapse,neuromuscular junction,synaptic vesicle & eye photoreceptor cell | somatic clone" FBgn0010109 dpn deadpan http://flybase.org/reports/FBgn0010109 FBgn0025271 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay" "sex determination, establishment of X:A ratio ; GO:0007540 | inferred from mutant phenotype inferred from genetic interaction with Sxl positive regulation of mitotic nuclear division ; GO:0045840 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype positive regulation of neuroblast proliferation ; GO:0002052 | inferred from mutant phenotype sex determination, establishment of X:A ratio ; GO:0007540 | non-traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement sex determination ; GO:0007530 | non-traceable author statement Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N inferred from genetic interaction with Su(H) larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay dosage compensation ; GO:0007549 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Dpn, CG8704, 44C, anon-EST:fe1B12, dpn, DPN, bHLHe50" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8704 11-Aug-17 DroID_v2017_08 "Drer\her7, Drer\hey1, Drer\her4.4, Drer\her2, Drer\bhlhe40, Drer\her15.1, Drer\heyl, Drer\hes2.1, Drer\her4.2, Drer\her11, Drer\her12, Drer\LOC100149863, Drer\her15.2, Drer\hes6, Drer\her4.3, Drer\her3, Drer\her8.2, Drer\helt, Drer\bhlhe41, Drer\hes2.2, Drer\hey2, Drer\her8a, Drer\her13, Drer\her9, Drer\her1, Drer\her5, Drer\her6" Scer\PHO4 "Cele\hlh-25, Cele\F52G2.3, Cele\hlh-27, Cele\lin-22" "Xtro\hes1, Xtro\hey1, Xtro\hes2, Xtro\hes4, Xtro\hey2, Xtro\hes7.1, Xtro\hes6.1, Xtro\bhlhe41, Xtro\bhlhe40, Xtro\hes7.2" "Mmus\Helt, Mmus\Hes7, Mmus\Hey1, Mmus\Heyl, Mmus\Hes3, Mmus\Hes6, Mmus\Hes1, Mmus\Hes2, Mmus\Hes5, Mmus\Bhlhe40, Mmus\Hey2, Mmus\Bhlhe41" "Hsap\HES4, Hsap\HEY1, Hsap\HES2, Hsap\HEYL, Hsap\HELT, Hsap\HES6, Hsap\HES3, Hsap\HES1, Hsap\BHLHE40, Hsap\HES7, Hsap\HEY2, Hsap\BHLHE41, Hsap\HES5" " larval stage , embryonic stage , embryonic stage | embryonic cycle 13 , embryonic stage&&larval stage " " sensory neuron imaginal disc

{ - da* } , neuroblast

, organism | pair rule

, external sensory organ

, central nervous system

, organism | gap

, peripheral nervous system

, neuron

{ $ AS-C- } , embryonic neuron

, ventral neurogenic region

" " embryonic stage | stage 8 , embryonic stage | embryonic cycle 13 , larval stage , embryonic stage&&larval stage , embryonic stage " " procephalic neurogenic region && Pcv7 neuroblast && Pcv9 neuroblast

, organism | pair rule

, organism | gap

, external sensory organ

, neuroblast

, embryonic antennal segment && ventral neurogenic region && neuroblast

, embryonic neuron

, central nervous system

, ventral neurogenic region

, peripheral nervous system

, sensory neuron imaginal disc

{ - da* } , neuron

{ $ AS-C- } " "flightless,neuroanatomy defective,size defective,lethal,recessive,polyphasic,behavior defective,increased cell number,cell lethal,germline clone,somatic clone,partially lethal - majority live,uncoordinated,visible" "type II neuroblast | third instar larval stage,adult brain,embryonic/larval optic lobe | third instar larval stage,type II neuroblast,embryonic/larval optic lobe,lamina,type I neuroblast,mushroom body neuroblast,macrochaeta,embryonic/larval neuroblast,secondary neuroblast,supernumerary,ganglion mother cell,somatic clone,wing" FBgn0267791 HnRNP-K Heterogeneous nuclear ribonucleoprotein K http://flybase.org/reports/FBgn0267791 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 mRNA binding ; GO:0003729 | traceable author statement transcription factor binding ; GO:0008134 | traceable author statement "cell proliferation ; GO:0008283 | traceable author statement imaginal disc growth ; GO:0007446 | traceable author statement appendage morphogenesis ; GO:0035107 | traceable author statement regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | traceable author statement" omega speckle ; GO:0035062 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from sequence or structural similarity nucleus ; GO:0005634 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 chromatin ; GO:0000785 | inferred from direct assay "Bancal, hnRNP-A1L, Hrb57A, hnRNP K, CG13425, BL, l(2)k08305, Q18, bl, dhnRNP K, HnRNP-K" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG13425 11-Aug-17 DroID_v2017_08 "Drer\zgc:110045, Drer\pcbp3, Drer\hnrpkl, Drer\pcbp2, Drer\hnrnpk, Drer\pcbp4" "Scer\HEK2, Scer\PBP2" "Cele\hrpk-1, Cele\C06G4.1, Cele\pes-4" "Xtro\pcbp2, Xtro\hnrnpk, Xtro\pcbp3" "Mmus\Hnrnpk, Mmus\Pcbp3, Mmus\Pcbp4, Mmus\Pcbp2, Mmus\Pcbp1" "Hsap\HNRNPK, Hsap\PCBP4, Hsap\PCBP2, Hsap\PCBP1, Hsap\PCBP3" " embryonic stage | <=10 hr , larval stage | third instar , larval stage&&pupal stage , adult stage | female , embryonic stage " " larval stage | third instar , embryonic stage " " imaginal disc

,

ubiquitous " DRSC22734 IE -1.698907134 0.798972119 -1.247340001 -2.420729614 0.269161219 -1.091553385 FBgn0015380 drl derailed http://flybase.org/reports/FBgn0015380 "FBgn0032764, FBgn0032765" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt5 Wnt-activated receptor activity ; GO:0042813 | traceable author statement protein homodimerization activity ; GO:0042803 | inferred from physical interaction with drl protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with dnt inferred from physical interaction with Drl-2 protein tyrosine kinase activity ; GO:0004713 | NOT inferred from key residues protein kinase binding ; GO:0019901 | inferred from physical interaction with Src64B "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR020635 memory ; GO:0007613 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | traceable author statement negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with Wnt5 signal transduction ; GO:0007165 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype axon guidance ; GO:0007411 | traceable author statement synapse assembly ; GO:0007416 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype mushroom body development ; GO:0016319 | traceable author statement chemorepulsion of axon ; GO:0061643 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype olfactory learning ; GO:0008355 | traceable author statement determination of muscle attachment site ; GO:0016204 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype haltere development ; GO:0007482 | inferred from genetic interaction with Ubx olfactory learning ; GO:0008355 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay receptor complex ; GO:0043235 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "derailed, Drl, lio, DRL, lin, lio/drl, CG17348, CG10758, drl" "IPR000719:Protein kinase domain, IPR003306:WIF domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG17348 11-Aug-17 DroID_v2017_08 "Drer\met, Drer\mst1rb, Drer\mst1ra, Drer\ryk" Scer\KIN1 "Cele\C24G6.2, Cele\F11E6.8, Cele\scd-2, Cele\kin-9, Cele\lin-18" Xtro\ryk "Mmus\Mst1r, Mmus\Met, Mmus\Ryk" "Hsap\MET, Hsap\RYK, Hsap\MST1R" " embryonic stage | 10-14 hr , embryonic stage " " abdominal 2--7 lateral transverse muscle 1

, interneuron

, abdominal 2--7 lateral transverse muscle 3

, abdominal 2--7 lateral transverse muscle 2

" " E | stage 11-15 , embryonic stage , larval stage | third instar , embryonic stage | 10-14 hr " " epidermis | restricted

, interneuron

, larval optic lobe

, abdominal 2--7 lateral transverse muscle 3

, abdominal 2--7 lateral transverse muscle 1

, larval brain | restricted

, abdominal 2--7 lateral transverse muscle 2

, anterior commissure

" "uncoordinated,viable,female fertile,male fertile,recessive,memory defective,neuroanatomy defective,lethal - all die before end of pupal stage,partially,some die during pupal stage,wild-type,behavior defective,neurophysiology defective,visible" "adult central complex,axon | embryonic stage,mushroom body alpha-lobe,mushroom body beta-lobe,fan-shaped body,adult mushroom body,perikaryon,adult brain,adult mushroom body beta'-lobe,ventral nerve cord commissure,longitudinal connective,lobe system of adult mushroom body,abdominal 1 lateral transverse muscle 1,abdominal 2 lateral transverse muscle 1,abdominal 3 lateral transverse muscle 1,abdominal 4 lateral transverse muscle 1,abdominal 5 lateral transverse muscle 1,abdominal 6 lateral transverse muscle 1,abdominal 7 lateral transverse muscle 1,abdominal 1 lateral transverse muscle 2,abdominal 2 lateral transverse muscle 2,abdominal 3 lateral transverse muscle 2,abdominal 4 lateral transverse muscle 2,abdominal 5 lateral transverse muscle 2,abdominal 6 lateral transverse muscle 2,abdominal 7 lateral transverse muscle 2,abdominal 1 lateral transverse muscle 3,abdominal 2 lateral transverse muscle 3,abdominal 3 lateral transverse muscle 3,abdominal 4 lateral transverse muscle 3,abdominal 5 lateral transverse muscle 3,abdominal 6 lateral transverse muscle 3,abdominal 7 lateral transverse muscle 3,mushroom body pedunculus,protocerebral bridge,optic lobe,embryonic/larval somatic muscle,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,anterior commissure,ventral nerve cord,presumptive embryonic salivary gland,antennal lobe,glomerulus,antennal lobe glomerulus DA1,antennal lobe glomerulus VA1,olfactory receptor neuron,pupa,lateral transverse muscle,embryonic/larval brain,protocerebrum,dorsal,mushroom body gamma-lobe,ellipsoid body,ring neuron,presumptive embryonic/larval central nervous system,posterior commissure,interneuron,embryonic ventral nervous system,chaeta,supernumerary" FBgn0003448 sna snail http://flybase.org/reports/FBgn0003448 FBgn0016654 protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with CtBP inferred from physical interaction with ebi sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II transcription corepressor activity ; GO:0001106 | contributes_to inferred from physical interaction with ebi RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay regulatory region DNA binding ; GO:0000975 | inferred from direct assay "gastrulation involving germ band extension ; GO:0010004 | traceable author statement ectoderm and mesoderm interaction ; GO:0007499 | non-traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | non-traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay inferred from mutant phenotype gastrulation ; GO:0007369 | non-traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype mesodermal cell fate determination ; GO:0007500 | traceable author statement central nervous system development ; GO:0007417 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype positive regulation of histone deacetylation ; GO:0031065 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype adherens junction organization ; GO:0034332 | inferred from mutant phenotype mesoderm development ; GO:0007498 | traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from direct assay asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with esg, wor ventral furrow formation ; GO:0007370 | inferred from genetic interaction with twi negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype mesodermal cell fate specification ; GO:0007501 | traceable author statement Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype mesoderm development ; GO:0007498 | non-traceable author statement" nucleus ; GO:0005634 | inferred from sequence or structural similarity inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity "sna, sn, BG:DS01845.1, l(2)35Db, l(2)br28, l35Db, br28, l(3)br28, CG3956, snail, Sna, Sco, SNA, br29, l(2)br29, SNAIL" IPR013087:Zinc finger C2H2-type CG3956 11-Aug-17 DroID_v2017_08 "Drer\scrt1b, Drer\snai1b, Drer\scrt1a, Drer\scrt2, Drer\snai3, Drer\snai1a, Drer\snai2" "Scer\USV1, Scer\AZF1, Scer\YPR015C, Scer\CMR3" "Cele\snai-1, Cele\ces-1, Cele\klu-1" "Xtro\snai1, Xtro\snai2" "Mmus\Scrt1, Mmus\Snai1, Mmus\Zfp747, Mmus\Snai3, Mmus\Egr3, Mmus\Snai2, Mmus\Scrt2" "Hsap\SNAI2, Hsap\SCRT1, Hsap\SNAI3, Hsap\SNAI1, Hsap\SCRT2" " embryonic stage | stage 11 , embryonic stage | stage 13 , embryonic stage , embryonic stage , embryonic stage | stage 5 , embryonic stage | cellular blastoderm , embryonic stage | stage 14-17 , larval stage | first instar , embryonic stage | cycle 14 , embryonic stage | stage 10 , embryonic stage | embryonic cycle 13 , embryonic stage | stage 11-14 , embryonic stage | stage 9-10 , embryonic stage | stage 6 , embryonic stage | stage 4 " " neuroblast

, ganglion mother cell

, head mesoderm

, mesoderm | presumptive

, dorsal mesothoracic disc | precursor

, Bolwig's organ | precursor

, embryonic peripheral nervous system

, dorsal mesothoracic disc

, mesoderm anlage

, dorsal metathoracic disc | precursor

, dorsal metathoracic disc

,

ventral , C1 chordotonal organ precursor cell

, neuroblast | precursor

, ventral neurogenic region | restricted

, organism | ventral & posterior

, central nervous system

" " embryonic stage | cellular blastoderm , embryonic stage | stage 13-15 , embryonic stage | stage 15 , embryonic stage , embryonic stage | stage 7 , embryonic stage | blastoderm , embryonic stage | stage 9-11 , embryonic stage | stage 6 , embryonic stage | stage 5 " " mesoderm | presumptive

, dorsal metathoracic disc | presumptive

, genital disc | presumptive

, embryonic neuron

, posterior transverse furrow

, cephalic furrow

, dorsal mesothoracic disc | presumptive

, anterior transverse furrow

, ventral neurogenic region

, anterior midgut proper primordium

, mesoderm

, ventral thoracic disc | presumptive

" "visible,dominant,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,neuroanatomy defective,viable" "scutellar bristle,ventral furrow,denticle belt,anterior scutellar bristle,posterior scutellar bristle,eye,ommatidium,interommatidial bristle,postalar bristle,dorsocentral bristle,notopleural bristle,upper humeral bristle,anterior postalar bristle,mesoderm,visceral mesoderm,cardioblast,embryonic/larval pericardial cell,precursor,endoderm,gastrula embryo,adult thorax,haltere,Malpighian tubule,Malpighian tubule tip cell,embryonic/larval hindgut,embryo,ventral,anterior midgut primordium,posterior midgut primordium,adult Malpighian tubule Type II cell,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,principal midgut epithelial cell,retina,scutellar bristle & trichogen cell455.2,scutellar bristle & tormogen cell455.2,embryonic/first instar larval cuticle,yolk" FBgn0024913 Actbeta Activin-beta http://flybase.org/reports/FBgn0024913 FBgn0065994 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR001839, InterPro:IPR017948 cytokine activity ; GO:0005125 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 transforming growth factor beta receptor binding ; GO:0005160 | non-traceable author statement transforming growth factor beta receptor binding ; GO:0005160 | inferred from biological aspect of ancestor with PANTHER:PTN000218063" cell development ; GO:0048468 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 cell growth ; GO:0016049 | non-traceable author statement regulation of MAPK cascade ; GO:0043408 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 SMAD protein signal transduction ; GO:0060395 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 positive regulation of pathway-restricted SMAD protein phosphorylation ; GO:0010862 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 dendrite morphogenesis ; GO:0048813 | non-traceable author statement extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 "Activin, dact, dAct, dACT, CG11062, anon-WO02059370.79, beta-Activin, Act, Actbeta, actbeta, activin-beta, dActivin, act, Act-beta" "IPR001839:Transforming growth factor-beta, C-terminal, IPR015615:Transforming growth factor-beta-related, IPR017948:Transforming growth factor beta, conserved site, IPR029034:Cystine-knot cytokine" CG11062 11-Aug-17 DroID_v2017_08 "Drer\bmp7b, Drer\lft2, Drer\bmp7a, Drer\gdf9, Drer\mstnb, Drer\tgfb2, Drer\gdf11, Drer\LOC100329520, Drer\bmp2a, Drer\tgfb1a, Drer\inhbab, Drer\lft1, Drer\gdf10b, Drer\gdf6a, Drer\bmp15, Drer\inhbb, Drer\spaw, Drer\inha, Drer\gdf6b, Drer\bmp3, Drer\gdf5, Drer\bmp10, Drer\gdf7, Drer\tgfb1b, Drer\admp, Drer\bmp2b, Drer\ndr1, Drer\bmp4, Drer\gdf2, Drer\LOC100332902, Drer\bmp10l, Drer\ndr2, Drer\amh, Drer\tgfb3, Drer\inhbaa, Drer\gdf10a, Drer\gdf3, Drer\tgfb2l, Drer\bmp6, Drer\mstna, Drer\bmp8a" - "Cele\dbl-1, Cele\tig-3, Cele\daf-7" "Xtro\bmp5, Xtro\gdf9, Xtro\bmp3, Xtro\nodal, Xtro\gdf10, Xtro\bmp8, Xtro\gdf2, Xtro\gdf3, Xtro\lefty, Xtro\inha, Xtro\gdf5, Xtro\bmp6, Xtro\bmp7.1, Xtro\nodal5, Xtro\mstn.1, Xtro\tgfb1, Xtro\nodal, Xtro\gdf11.1, Xtro\inhba, Xtro\nodal1, Xtro\bmp10, Xtro\bmp4, Xtro\bmp7.2, Xtro\bmp2, Xtro\inhbc.1, Xtro\tgfb2, Xtro\gdf7, Xtro\admp, Xtro\bmp15, Xtro\nodal6, Xtro\gdf1" "Mmus\Gdf7, Mmus\Gdf1, Mmus\Inhbe, Mmus\Amh, Mmus\Gdf15, Mmus\Gdf11, Mmus\Bmp8a, Mmus\Bmp7, Mmus\Inhbc, Mmus\Gdf3, Mmus\Gdf9, Mmus\Tgfb2, Mmus\Gdf2, Mmus\Bmp8b, Mmus\Bmp6, Mmus\Inha, Mmus\Mstn, Mmus\Gdf5, Mmus\Nodal, Mmus\Bmp5, Mmus\Tgfb3, Mmus\Gdf6, Mmus\Lefty2, Mmus\Bmp15, Mmus\Bmp2, Mmus\Tgfb1, Mmus\Bmp3, Mmus\Bmp10, Mmus\Inhbb, Mmus\Bmp4, Mmus\Inhba, Mmus\Lefty1, Mmus\Gdf10" "Hsap\BMP8A, Hsap\BMP7, Hsap\GDF15, Hsap\NODAL, Hsap\BMP15, Hsap\GDF5, Hsap\LEFTY2, Hsap\GDF2, Hsap\GDF3, Hsap\GDF9, Hsap\BMP4, Hsap\GDF11, Hsap\TGFB2, Hsap\BMP10, Hsap\TGFB3, Hsap\INHA, Hsap\GDF10, Hsap\BMP6, Hsap\TGFB1, Hsap\MSTN, Hsap\AMH, Hsap\LEFTY1, Hsap\BMP3, Hsap\INHBA, Hsap\GDF7, Hsap\BMP8B, Hsap\INHBB, Hsap\BMP5, Hsap\GDF6, Hsap\BMP2, Hsap\INHBC, Hsap\INHBE, Hsap\GDF1" " embryonic stage , embryonic stage&&larval stage&&adult stage " " embryonic central nervous system

, sensory mother cell

, ventral nerve cord

, neuroblast

, embryonic peripheral nervous system

" "lethal,recessive,visible,neuroanatomy defective,cell growth defective,viable,circadian rhythm defective,heat sensitive" "wing vein,distal medullary amacrine neuron Dm8,optic lobe,photoreceptor cell R7,somatic clone,central nervous system,wing" FBgn0020912 Ptx1 Ptx1 http://flybase.org/reports/FBgn0020912 - protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with MGI:MGI:109340 sequence-specific DNA binding ; GO:0043565 | inferred from sequence or structural similarity with MGI:MGI:109340" dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:109340 transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGI:MGI:109340 nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:109340 nucleus ; GO:0005634 | inferred from direct assay "Ptx, ptx1, D-Ptx1, CG1447, Ptx1" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR003654:OAR domain, IPR009057:Homeobox domain-like" CG1447 11-Aug-17 DroID_v2017_08 "Drer\pitx1, Drer\pitx2, Drer\pitx3" "Scer\YOX1, Scer\PHO2" "Cele\npax-4, Cele\unc-42, Cele\unc-30" "Xtro\pitx3, Xtro\pitx1, Xtro\pitx2" "Mmus\Pitx3, Mmus\Rhox11, Mmus\Pitx1, Mmus\Rhox8, Mmus\Pitx2" "Hsap\PITX2, Hsap\PITX3, Hsap\PITX1" " embryonic stage | stage 4 , embryonic stage | stage 8 " "

posterior , proctodeum

,

0-10% egg length " " embryonic stage | stage 11-13 , embryonic stage | stage 16 , embryonic stage | stage 15 " " midgut

, central nervous system | segmentally repeated

, somatic muscle | segmentally repeated

, midgut constriction 2

" viable FBgn0003719 tld tolloid http://flybase.org/reports/FBgn0003719 - protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR015446 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 metalloendopeptidase activity ; GO:0004222 | non-traceable author statement" "amnioserosa formation ; GO:0007378 | non-traceable author statement protein processing ; GO:0016485 | inferred from direct assay regulation of transforming growth factor beta receptor signaling pathway ; GO:0017015 | traceable author statement positive regulation of BMP signaling pathway ; GO:0030513 | traceable author statement terminal region determination ; GO:0007362 | inferred from genetic interaction with tor torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor maternal specification of dorsal/ventral axis, oocyte, soma encoded ; GO:0007313 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype proteolysis ; GO:0006508 | non-traceable author statement embryonic pattern specification ; GO:0009880 | traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from direct assay" extracellular region ; GO:0005576 | non-traceable author statement "CG6868, Tolloid, Tld, CT21278, tld, TLD, dTld" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR000859:CUB domain, IPR001506:Peptidase M12A, IPR001881:EGF-like calcium-binding domain, IPR006026:Peptidase, metallopeptidase, IPR013032:EGF-like, conserved site, IPR015446:Bone morphogenetic protein 1/tolloid-like protein, IPR024079:Metallopeptidase, catalytic domain, IPR034036:Tolloid/BMP1 peptidase domain" CG6868 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-40a17.3, Drer\LOC797085, Drer\mep1a.2, Drer\c6ast4, Drer\npsn, Drer\he2, Drer\he1b, Drer\tnfaip6, Drer\bmp1a, Drer\LOC100003133, Drer\c6ast1, Drer\mep1b, Drer\mep1a.1, Drer\tll1, Drer\bmp1b, Drer\c6ast3, Drer\he1a" - "Cele\nas-14, Cele\nas-39, Cele\nas-13, Cele\nas-12, Cele\nas-6, Cele\Y19D10A.6, Cele\ZC116.3, Cele\nas-7, Cele\nas-8, Cele\nas-15, Cele\nas-1, Cele\nas-4, Cele\clec-57, Cele\nas-2, Cele\nas-3" "Xtro\LOC100489456, Xtro\tll2, Xtro\mep1b, Xtro\LOC100492324, Xtro\tll1, Xtro\tnfaip6, Xtro\mep1a, Xtro\bmp1, Xtro\accs, Xtro\uvs.2, Xtro\cubn" "Mmus\Mep1a, Mmus\Pcolce2, Mmus\Tll2, Mmus\Bmp1, Mmus\Tnfaip6, Mmus\Astl, Mmus\Tll1, Mmus\Adgrg6, Mmus\Cubn, Mmus\Mep1b" "Hsap\MEP1B, Hsap\TLL1, Hsap\TLL2, Hsap\ADGRG6, Hsap\CUBN, Hsap\PCOLCE2, Hsap\ASTL, Hsap\TNFAIP6, Hsap\BMP1, Hsap\MEP1A" " larval stage | third instar , embryonic stage | stage 8-9 , embryonic stage | early , embryonic stage , embryonic stage | stage 11 , embryonic stage | cellular blastoderm " " imaginal disc

, embryonic maxillary segment | restricted

,

dorsal , eye-antennal disc

, embryonic labial segment | restricted

, larval optic lobe

, tracheal pit

, morphogenetic furrow | anterior to

, embryonic central nervous system | primordium | restricted

, embryonic mandibular segment | restricted

" embryonic stage | blastoderm

dorsal "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,wild-type,visible,lethal - all die before end of pupal stage,temperature conditional,some die during pupal stage,heat sensitive,viable" "embryonic leading edge cell,embryonic epidermis,ommatidium,brain,epidermis,dorsal,amnioserosa,embryo,cephalic furrow,extended germ band embryo,denticle belt,egg operculum,maternal effect,somatic clone,dorsal appendage,embryonic ventral epidermis,embryonic dorsal epidermis,polytene chromosome,visceral mesoderm,embryonic/larval dorsal vessel,posterior crossvein,wing vein,wing" FBgn0259209 Mlp60A Muscle LIM protein at 60A http://flybase.org/reports/FBgn0259209 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 muscle tissue development ; GO:0060537 | inferred from expression pattern nucleus ; GO:0005634 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay actin cytoskeleton ; GO:0015629 | colocalizes_with inferred from direct assay "CG42309, DMlp1, dMlp60A, MLP1, DMLP1, DmLIM-2, Mlp1, MLP, DLim-2, CG33149, BcDNA:RH74176, BcDNA:RE14544, Mlp60A, CG30174, CG3220, CG30179, Mlp60, FBgn0259209, MLIM 60A" "IPR001781:Zinc finger, LIM-type" CG42309 11-Aug-17 DroID_v2017_08 "Drer\zgc:195282, Drer\crip1, Drer\csrp1a, Drer\csrp2, Drer\csrp3, Drer\csrp1b" Scer\LRG1 Cele\mlp-1 "Xtro\crip1, Xtro\csrp1, Xtro\csrp3, Xtro\csrp2" "Mmus\Csrp1, Mmus\Crip1, Mmus\Csrp2, Mmus\Csrp3" "Hsap\CSRP2, Hsap\CSRP1, Hsap\CSRP3, Hsap\CRIP1" " embryonic stage | stage >=13 , embryonic stage | stage >=14 , embryonic stage | stage 16 , embryonic stage , embryonic stage -- adult stage " " visceral mesoderm

, somatic mesoderm

, embryonic/larval somatic muscle

, pharyngeal muscle

" embryonic stage " pharyngeal muscle

, embryonic/larval somatic muscle

, larval visceral muscle

" FBgn0264442 ab abrupt http://flybase.org/reports/FBgn0264442 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement" "dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype axon choice point recognition ; GO:0016198 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype" nucleus ; GO:0005634 | non-traceable author statement inferred from direct assay "ab, CG43860, B2149, CG4807, clu, ptd, l(2)k02807, Ab, CG32830" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR013087:Zinc finger C2H2-type, IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG43860 11-Aug-17 DroID_v2017_08 "Drer\zbtb20, Drer\zbtb37, Drer\zbtb34, Drer\zbtb22b" - - - "Mmus\Zbtb34, Mmus\Zbtb20, Mmus\Zbtb22, Mmus\Zbtb12, Mmus\Zbtb6, Mmus\Zbtb26, Mmus\Zbtb45, Mmus\Zbtb37, Mmus\Zbtb7b, Mmus\Zbtb43, Mmus\Zbtb7a" "Hsap\ZBTB37, Hsap\ZBTB9, Hsap\ZBTB12, Hsap\ZBTB22, Hsap\ZBTB43, Hsap\ZBTB34, Hsap\ZBTB26, Hsap\ZBTB6" " larval stage , embryonic stage | stage >=9 , embryonic stage , embryonic stage | stage >=14 , embryonic stage | stage >=11 " " eye-antennal disc

, ventral midline

, dorsal mesothoracic disc

, embryonic stomatogastric nervous system

, larval muscle system

, imaginal disc

, epidermis

, VUM precursor

" " larval stage , embryonic stage | stage >=14 , embryonic stage , embryonic stage | stage >=11 , embryonic stage | stage >=9 " " eye-antennal disc

, imaginal disc

, dorsal mesothoracic disc

, larval muscle system

, embryonic stomatogastric nervous system

, epidermis

, ventral midline

, VUM precursor

" FBgn0000071 Ama Amalgam http://flybase.org/reports/FBgn0000071 FBgn0015757 protein_coding_gene - - plasma membrane ; GO:0005886 | inferred from sequence or structural similarity inferred from direct assay "Ama, CG2198, ama, CT7244, AMA, M109, BG:DS00276.6" "IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain" CG2198 11-Aug-17 DroID_v2017_08 "Drer\vsig8a, Drer\lrit1b, Drer\itgb4, Drer\jam2a, Drer\f11r.1, Drer\zgc:153073, Drer\si:dkey-250k15.10, Drer\si:ch1073-459j12.1, Drer\si:ch211-215e19.3, Drer\vsig8b, Drer\zgc:110372, Drer\igsf11, Drer\cxadr, Drer\kirrel3a, Drer\jam2b, Drer\si:zfos-1011f11.1, Drer\pigrl4.2, Drer\gpa33, Drer\f11r.2, Drer\LOC100151468, Drer\jam3b, Drer\opcml, Drer\kirrela, Drer\mxra8a, Drer\lrit1a, Drer\ntm, Drer\sdk1a, Drer\kirrelb, Drer\cxcr3.1, Drer\lrit3a, Drer\sdk1b, Drer\ncam1b, Drer\kirrel3l, Drer\lrit3b, Drer\ush2a, Drer\kirrel3b, Drer\mxra8b, Drer\igsf9bb, Drer\dscama, Drer\esama, Drer\paplna, Drer\si:ch211-9d9.7, Drer\si:dkey-65b12.12, Drer\jam3a, Drer\esamb, Drer\igsf9a" - "Cele\rig-5, Cele\zig-10, Cele\zig-3" "Xtro\kirrel2, Xtro\icam5, Xtro\lsamp, Xtro\papln, Xtro\lrit3, Xtro\negr1, Xtro\igsf9b, Xtro\ntm" "Mmus\Opcml, Mmus\Lrit1, Mmus\Jam2, Mmus\Gpa33, Mmus\Vsig2, Mmus\Clmp, Mmus\Lrit3, Mmus\Kirrel, Mmus\Sdk1, Mmus\Cxadr, Mmus\Igsf5, Mmus\Ntm, Mmus\Vsir, Mmus\Jam3, Mmus\Vsig8, Mmus\Hepacam2, Mmus\Papln, Mmus\Iglon5, Mmus\Vsig1, Mmus\Esam, Mmus\Ptprq, Mmus\Gm1123, Mmus\Igsf11, Mmus\Lsamp, Mmus\Igsf9b, Mmus\Kirrel3, Mmus\Mxra8, Mmus\Negr1, Mmus\F11r, Mmus\Kirrel2" "Hsap\KIRREL3, Hsap\IGSF11, Hsap\LRIT1, Hsap\F11R, Hsap\IGSF5, Hsap\JAM3, Hsap\VSIG8, Hsap\CXADR, Hsap\KIRREL, Hsap\MXRA8, Hsap\NTM, Hsap\JAM2, Hsap\KIRREL2, Hsap\IGLON5, Hsap\PAPLN, Hsap\OPCML, Hsap\C10orf54, Hsap\VSIG2, Hsap\ESAM, Hsap\C1orf204, Hsap\GPA33, Hsap\VSIG1, Hsap\USH2A, Hsap\LSAMP, Hsap\CLMP, Hsap\LRIT3, Hsap\SDK1, Hsap\IGSF9B" " embryonic stage , pupal stage " " embryonic stage | stage >=10 , embryonic stage | stage >=13 , embryonic stage | stage 16 , embryonic stage | stage 8 , embryonic stage | stage 13 , embryonic stage | stage 10 " " embryonic central nervous system | presumptive

, peripheral nervous system

, larval labral segment sense organ | precursor

, mesoderm

, spiracular sensory organ

, amnioserosa

, fat body

, embryonic/larval dorsal vessel

, visceral mesoderm

, hypophysis

, neuron

" partially lethal - majority die FBgn0015553 tos tosca http://flybase.org/reports/FBgn0015553 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR008918, InterPro:IPR020045 single-stranded DNA 5'-3' exodeoxyribonuclease activity ; GO:0045145 | inferred from sequence or structural similarity with UniProtKB:Q9UQ84 5'-3' exonuclease activity ; GO:0008409 | inferred from sequence or structural similarity with UniProtKB:P53695 flap endonuclease activity ; GO:0048256 | inferred from sequence or structural similarity with UniProtKB:Q9UQ84 double-stranded DNA 5'-3' exodeoxyribonuclease activity ; GO:0051908 | inferred from sequence or structural similarity with UniProtKB:Q9UQ84" mismatch repair ; GO:0006298 | inferred from sequence or structural similarity with UniProtKB:Q9UQ84 mismatch repair ; GO:0006298 | inferred from sequence or structural similarity with UniProtKB:P53695 DNA recombination ; GO:0006310 | inferred from sequence or structural similarity with UniProtKB:Q9UQ84 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9UQ84 "DmTosca, Tosca, CG10387, tos" "IPR006085:XPG N-terminal, IPR006086:XPG-I domain, IPR008918:Helix-hairpin-helix motif, class 2, IPR019974:XPG conserved site, IPR020045:5'-3' exonuclease, C-terminal domain, IPR006084:XPG/Rad2 endonuclease, IPR029060:PIN domain-like, IPR032641:Exonuclease 1" CG10387 11-Aug-17 DroID_v2017_08 Drer\exo1 "Scer\EXO1, Scer\YEN1, Scer\DIN7" Cele\exo-1 Xtro\exo1 Mmus\Exo1 Hsap\EXO1 " adult stage && oogenesis stage , adult stage && oogenesis stage | stage S1-6 , embryonic stage | 0-4 hr , adult stage && oogenesis stage | stage S11-14 , adult stage | female , adult stage && oogenesis stage | stage S9,10 " " germarium region 2a

, oocyte | ubiquitous

, germarium region 2b

, germarium region 3

, border follicle cell

" viable FBgn0025878 wrapper wrapper http://flybase.org/reports/FBgn0025878 - protein_coding_gene - glial cell apoptotic process ; GO:0034349 | inferred from mutant phenotype axon ensheathment ; GO:0008366 | inferred from mutant phenotype axon development ; GO:0061564 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "CG10382, CT19059, wrapper, Wr, Wrapper" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain" CG10382 11-Aug-17 DroID_v2017_08 "Drer\ntm, Drer\negr1, Drer\opcml, Drer\zgc:110372" Scer\OPY2 Cele\wrk-1 "Xtro\lsamp, Xtro\ntm, Xtro\negr1" "Mmus\Fgfrl1, Mmus\Ntm, Mmus\Opcml, Mmus\Iglon5, Mmus\Negr1, Mmus\Lsamp" "Hsap\NEGR1, Hsap\IGLON5, Hsap\LSAMP, Hsap\OPCML, Hsap\NTM" " embryonic stage | stage 17 , larval stage | third instar , embryonic stage | stage >=12 " " glial cell &&of embryonic brain

, ventral midline

, midline glial cell

, larval brain

, PNS glial cell

" " embryonic stage | stage 17 , larval stage | third instar , embryonic stage | stage >=12 " " glial cell &&of embryonic brain

, larval brain

, ventral midline

, midline glial cell

" "viable,fertile" "ventral nerve cord commissure,midline glial cell,presumptive embryonic/larval central nervous system" FBgn0003900 twi twist http://flybase.org/reports/FBgn0003900 "FBtr0071953, FBpp0071864" protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:P11420 DNA binding ; GO:0003677 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from genetic interaction with dl protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P10627 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | non-traceable author statement muscle fiber development ; GO:0048747 | inferred from mutant phenotype mesodermal cell fate commitment ; GO:0001710 | traceable author statement mesodermal cell fate specification ; GO:0007501 | traceable author statement mesoderm development ; GO:0007498 | inferred from expression pattern mesoderm development ; GO:0007498 | traceable author statement gastrulation ; GO:0007369 | inferred from mutant phenotype ventral furrow formation ; GO:0007370 | inferred from genetic interaction with sna ectoderm and mesoderm interaction ; GO:0007499 | non-traceable author statement mesodermal cell fate determination ; GO:0007500 | traceable author statement gastrulation involving germ band extension ; GO:0010004 | traceable author statement salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype dorsal/ventral axis specification ; GO:0009950 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay mesodermal cell fate commitment ; GO:0001710 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement actomyosin structure organization ; GO:0031032 | inferred from mutant phenotype gastrulation ; GO:0007369 | non-traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from direct assay regulation of striated muscle tissue development ; GO:0016202 | inferred from mutant phenotype mesoderm development ; GO:0007498 | non-traceable author statement ventral furrow formation ; GO:0007370 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "twi, CG2956, DTwist, dip5, EC9, Twi, TWI, bHLHb17, twist, Tw, Twist" "IPR015789:Twist-related, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG2956 11-Aug-17 DroID_v2017_08 "Drer\hand2, Drer\twist2, Drer\twist1b, Drer\twist1a, Drer\twist3" - Cele\hlh-8 "Xtro\twist1, Xtro\hand1, Xtro\twist2, Xtro\hand2" "Mmus\Twist2, Mmus\Hand1, Mmus\Hand2, Mmus\Twist1, Mmus\Atoh8" "Hsap\TWIST1, Hsap\HAND1, Hsap\BHLHE23, Hsap\TWIST2, Hsap\ATOH8, Hsap\HAND2, Hsap\MYF6" " embryonic stage | 2-10 hr , embryonic stage | cellular blastoderm , embryonic stage | stage 6 , embryonic stage | stage 8 , embryonic stage | stage 5 " " ectoderm | presumptive

, mesoderm | presumptive

, mesoderm

,

ventral compartment " " embryonic stage | stage 7-10 , embryonic stage | cellular blastoderm , embryonic stage | stage 6 , embryonic stage | stage 12-14 , embryonic stage--pupal stage , embryonic stage | stage 5 , embryonic stage | stage 7-8 " " mesoderm

, ectoderm | presumptive

, mesoderm | presumptive

, larval visceral muscle

, mesectoderm

, mesothoracic tergum && myoblast

, embryonic/larval somatic muscle

,

ventral , anterior midgut proper primordium

" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,visible,heat sensitive,neuroanatomy defective,flight defective,viable" "principal midgut epithelial cell,ventral furrow,embryo,ventral,visceral mesoderm,endoderm,dorsal medial muscle,oblique muscle,wing,mesothoracic extracoxal depressor muscle 66,skeletal muscle of abdomen,embryonic/larval somatic muscle,indirect flight muscle,direct flight muscle,heat sensitive,anterior midgut primordium,posterior midgut primordium,longitudinal visceral muscle primordium,circular visceral muscle fiber,embryonic somatic muscle,visceral muscle primordium,embryonic/larval pericardial cell,embryonic/larval heart,ectopic,Malpighian tubule,presumptive embryonic/larval central nervous system,mesoderm,central nervous system,embryonic/larval dorsal branch,embryonic/larval dorsal trunk,corpus cardiacum primordium,presumptive embryonic salivary gland,visceral muscle,embryonic/larval dorsal vessel | embryonic stage,cardioblast,abdominal ventral transverse muscle 1 founder cell,abdominal lateral oblique muscle 1 founder cell,embryonic epidermis,myoblast | P-stage" FBgn0261836 Msp300 Muscle-specific protein 300 kDa http://flybase.org/reports/FBgn0261836 protein_coding_gene actin filament binding ; GO:0051015 | inferred from electronic annotation with InterPro:IPR030265 protein binding ; GO:0005515 | inferred from physical interaction with klar actin binding ; GO:0003779 | inferred from direct assay protein kinase binding ; GO:0019901 | inferred from physical interaction with sls cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from sequence or structural similarity "cytoskeletal anchoring at nuclear membrane ; GO:0090286 | inferred from electronic annotation with InterPro:IPR030265 establishment of nucleus localization ; GO:0040023 | inferred from mutant phenotype nucleus localization ; GO:0051647 | inferred from genetic interaction with klar cell migration ; GO:0016477 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype microtubule anchoring ; GO:0034453 | inferred from genetic interaction with klar female germline ring canal stabilization ; GO:0008335 | inferred from mutant phenotype mitochondrion localization ; GO:0051646 | inferred from mutant phenotype endoplasmic reticulum localization ; GO:0051643 | inferred from mutant phenotype mesoderm development ; GO:0007498 | non-traceable author statement larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype nucleus organization ; GO:0006997 | inferred from genetic interaction with klar actin filament organization ; GO:0007015 | inferred from mutant phenotype skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype" LINC complex ; GO:0034993 | inferred from electronic annotation with InterPro:IPR030265 Z disc ; GO:0030018 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay integrin complex ; GO:0008305 | colocalizes_with inferred from direct assay actin cytoskeleton ; GO:0015629 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay actin filament ; GO:0005884 | colocalizes_with inferred from direct assay nuclear outer membrane ; GO:0005640 | inferred from direct assay "Msp-300, msp300, CG33715, CG42768, CG14035, FBgn0010070, MSP-300, CG18252, MSP300, jf22, CG31649, BcDNA:AT10293, BcDNA:GH18470, l(2)jf22, l(2)25Ch, Spec25CD, CG18251, BcDNA:LP10936, BcDNA:GH02446, CG31916, CG33549, msp-300, Msp300, BBF-1, Bbbf1, dNesp1" "IPR030265:Nesprin-1, IPR018159:Spectrin/alpha-actinin, IPR002017:Spectrin repeat, IPR012315:KASH domain, IPR001715:Calponin homology domain, IPR001589:Actinin-type actin-binding domain, conserved site" CG42768 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-137a8.2, Drer\dst, Drer\eppk1, Drer\dspa, Drer\micall2b, Drer\pleca, Drer\zgc:100997, Drer\aspm, Drer\clmn, Drer\smtnb, Drer\syne1a, Drer\syne2b, Drer\macf1a, Drer\syne2a, Drer\syne1b, Drer\micall1a, Drer\micall2a, Drer\gas2b, Drer\wu:fi04e12, Drer\smtna" - Cele\anc-1 "Xtro\plec, Xtro\gas2l2, Xtro\syne1, Xtro\syne2, Xtro\dst, Xtro\macf1" "Mmus\Syne1, Mmus\Macf1, Mmus\Dst, Mmus\Smtnl2, Mmus\Clmn, Mmus\Micalcl, Mmus\Smtn, Mmus\Syne2, Mmus\Plec, Mmus\Smtnl1, Mmus\Aspm" "Hsap\SMTNL2, Hsap\SYNE2, Hsap\MACF1, Hsap\EVPLL, Hsap\SMTNL1, Hsap\GAS2L1, Hsap\CLMN, Hsap\SYNE3, Hsap\GAS2L2, Hsap\SMTN, Hsap\ASPM, Hsap\MICALCL, Hsap\PLEC, Hsap\SYNE1" " larval stage , adult stage , embryonic stage " embryonic stage " muscle attachment site

, larval visceral muscle

, larval muscle system

" FBgn0263237 Cdk7 Cyclin-dependent kinase 7 http://flybase.org/reports/FBgn0263237 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | contributes_to inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | contributes_to inferred from direct assay cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000624096 regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from direct assay programmed cell death ; GO:0012501 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement "holo TFIIH complex ; GO:0005675 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:1778 inferred from sequence or structural similarity with SGD:S000002266 cytoplasm ; GO:0005737 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from physical interaction with hay, CycH, Mat1, mrn, Xpd carboxy-terminal domain protein kinase complex ; GO:0032806 | inferred from direct assay TFIIK complex ; GO:0070985 | inferred from biological aspect of ancestor with PANTHER:PTN000624096 nucleus ; GO:0005634 | inferred from direct assay" "CG3319, Cdk7, cdk7, CDK7, DmMO15, p40[MO15], DmCdk7, Dmcdk7, DmCDK7, cdk-7, dCdk7, DmMo15, Mo15, CD 7" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG3319 11-Aug-17 DroID_v2017_08 "Drer\cdk7, Drer\cdk20" "Scer\KIN28, Scer\SNF1" "Cele\cdk-7, Cele\dyf-18" Xtro\cdk7 "Mmus\Cdk20, Mmus\Cdk7" "Hsap\CDK20, Hsap\CDK7" " adult stage | female , embryonic stage -- adult stage " ovary

FBgn0261385 scra scraps http://flybase.org/reports/FBgn0261385 protein_coding_gene actin binding ; GO:0003779 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity microtubule binding ; GO:0008017 | inferred from direct assay myosin binding ; GO:0017022 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Synd septin ring organization ; GO:0031106 | inferred from mutant phenotype regulation of cytokinesis ; GO:0032465 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype cytokinesis ; GO:0000910 | inferred from mutant phenotype maintenance of actomyosin contractile ring localization ; GO:0032189 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype plasma membrane organization ; GO:0007009 | inferred from mutant phenotype sensory organ precursor cell division ; GO:0045035 | inferred from mutant phenotype positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from mutant phenotype intercellular bridge organization ; GO:0043063 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype male germline ring canal formation ; GO:0030726 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype germline ring canal ; GO:0045172 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay male germline ring canal ; GO:0035323 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay actomyosin contractile ring ; GO:0005826 | inferred from direct assay contractile ring ; GO:0070938 | inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay "scra, anillin, ani, CG2092, Ani, l(2)43Ec, ABP8, l(2)03427, Abp8, Scra, Anillin, l(2)k08255, anil, Anil" "IPR012966:Anillin homology domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR031970:Anillin, N-terminal domain" CG2092 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-30c15.10, Drer\anln" - "Cele\ani-2, Cele\ani-3, Cele\ani-1" Xtro\anln Mmus\Anln Hsap\ANLN " , embryonic stage -- adult stage " cell

DRSC07679 K 0.303458739 0.006738071 0.279153167 -0.139493592 0.639625796 1.812448036 FBgn0019643 Dat Dopamine N acetyltransferase http://flybase.org/reports/FBgn0019643 FBgn0000418 protein_coding_gene aralkylamine N-acetyltransferase activity ; GO:0004059 | inferred from direct assay N-acetyltransferase activity ; GO:0008080 | inferred from direct assay aralkylamine N-acetyltransferase activity ; GO:0004059 | traceable author statement arylamine N-acetyltransferase activity ; GO:0004060 | inferred from direct assay "sleep ; GO:0030431 | traceable author statement serotonin catabolic process ; GO:0042429 | non-traceable author statement catecholamine metabolic process ; GO:0006584 | inferred from direct assay sleep ; GO:0030431 | inferred from expression pattern octopamine catabolic process ; GO:0046334 | non-traceable author statement regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | traceable author statement dopamine catabolic process ; GO:0042420 | non-traceable author statement developmental pigmentation ; GO:0048066 | traceable author statement" cytoplasm ; GO:0005737 | inferred from direct assay "Dat, aaNAT, Dat1, AA-NAT1, aaNat, NAT1, aaNAT1, CG3318, Aanat1, AANAT, AANATA, AANATB, DAT" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG3318 11-Aug-17 DroID_v2017_08 - - "Cele\M7.12, Cele\T09F5.10, Cele\F10G2.7, Cele\C28D4.4, Cele\R05H10.1, Cele\F36D3.8, Cele\W02D7.5, Cele\M7.8, Cele\anat-1, Cele\R13D11.4, Cele\R05H10.7, Cele\W02D7.4, Cele\T10B5.4, Cele\C28D4.7, Cele\C28D4.5" - - - " embryonic stage , embryonic stage | stage >=15 , embryonic stage | stage >=14 " " tracheal system

, anterior embryonic/larval midgut

, embryonic brain

, embryonic central nervous system

, embryonic nervous system

, oenocyte

, amnioserosa

, posterior embryonic/larval midgut

, ventral nerve cord

, proventriculus

" "behavior defective,recessive,lethal" FBgn0000927 fs(1)Ya female sterile (1) Young arrest http://flybase.org/reports/FBgn0000927 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Lam DNA replication ; GO:0006260 | inferred from genetic interaction with gnu nucleus organization ; GO:0006997 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype nuclear division ; GO:0000280 | traceable author statement chromatin assembly or disassembly ; GO:0006333 | inferred from mutant phenotype pronuclear fusion ; GO:0007344 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype nuclear lamina ; GO:0005652 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay nuclear lamina ; GO:0005652 | colocalizes_with inferred from direct assay inferred from physical interaction with Lam "YA, Ya, EG:95B7.4, CG2707, fs(1)Y[a], fs(1)73, fs(1)Y2, fs(1)M12, fs(1)Ya" - CG2707 11-Aug-17 DroID_v2017_08 - - - - - - " embryonic stage | 0-2 hr , adult stage && oogenesis stage " " oocyte

, nurse cell

" " embryonic stage , adult stage && oogenesis stage , embryonic stage | stage 1-4 " " polar body nucleus

, nurse cell

, organism

, male pronucleus

, oocyte

, ovary

, yolk nucleus

, female pronucleus

" "viable,fertile,wild-type,electrophoretic variant,female sterile,recessive,fully,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,partially,cell cycle defective,female fertile" "egg,maternal effect,embryo,cell cycle,fertilized egg,unfertilized egg" FBgn0019990 Gcn2 Gcn2 http://flybase.org/reports/FBgn0019990 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement elongation factor-2 kinase activity ; GO:0004686 | inferred from direct assay" "protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of cell size ; GO:0045793 | inferred from genetic interaction with gig mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of translation ; GO:0006417 | inferred by curator from GO:0004686" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay cytosol ; GO:0005829 | inferred by curator from GO:0004686 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "DGCN2, GCN2, dGCN2, CG1609, Gcn2, Gcn-2, gcn2" "IPR000719:Protein kinase domain, IPR006575:RWD domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR017441:Protein kinase, ATP binding site" CG1609 11-Aug-17 DroID_v2017_08 Drer\eif2ak4 Scer\GCN2 Cele\gcn-2 Xtro\eif2ak4 "Mmus\Eif2ak1, Mmus\Eif2ak4" "Hsap\EIF2AK4, Hsap\EIF2AK1" " embryonic stage | early , embryonic stage | stage >=12 , embryonic stage | stage 8-11 , embryonic stage | stage 14 , embryonic stage | stage 6 , embryonic stage | late , embryonic stage | stage 12-14 , embryonic stage | stage >=13 , embryonic stage -- adult stage , embryonic stage | stage 16-17 " " embryonic central nervous system

, mesoderm

, embryonic/larval hindgut

, posterior midgut proper primordium

, amnioproctodeal invagination

, neuron

, anterior midgut proper primordium

, cephalic furrow

, ventral furrow

, anterior embryonic/larval midgut

, embryonic brain | primordia

, anterior transverse furrow

, embryonic central nervous system | restricted

, posterior embryonic/larval midgut

, posterior transverse furrow

, ventral nerve cord

" "immune response defective,majority die during P-stage,viable" FBgn0086680 vvl ventral veins lacking http://flybase.org/reports/FBgn0086680 protein_coding_gene "transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001228 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "dendrite morphogenesis ; GO:0048813 | traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay brain development ; GO:0007420 | inferred from mutant phenotype epithelial cell fate determination, open tracheal system ; GO:0007425 | traceable author statement motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype positive regulation of antimicrobial peptide biosynthetic process ; GO:0002807 | inferred from direct assay brain segmentation ; GO:0035284 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "vvl, ut, Dfr/Vvl, Vv1, dfr, Cf1a, VVL, DFR, dfr-vvl, dfr/vvl, Cfla, Cf1a/drifter, drf, Cf1-a, vvl/dfr/ut, prd3, CG10037, sep, Vvl, vvl/dfr, Drf, Dfr, CF1A" "IPR017970:Homeobox, conserved site, IPR000327:POU-specific domain, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR010982:Lambda repressor-like, DNA-binding domain, IPR013847:POU domain, IPR016362:POU-domain transcription factor, class 3, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG10037 11-Aug-17 DroID_v2017_08 "Drer\pou2f1b, Drer\pou3f2a, Drer\lmx1bb, Drer\pou3f1, Drer\pou2f1a, Drer\pou3f3a, Drer\lmx1a, Drer\pou6f1, Drer\lmx1ba, Drer\pou5f3, Drer\hoxa9b, Drer\pou2f2a, Drer\pou3f3b, Drer\pou2f3, Drer\pou1f1, Drer\hoxb7a, Drer\pou3f2b" "Scer\YHP1, Scer\YOX1" "Cele\lim-6, Cele\ceh-18, Cele\ceh-6, Cele\php-3" "Xtro\hoxa7, Xtro\pou2f3, Xtro\pou3f3, Xtro\pou6f2, Xtro\pou3f4, Xtro\pou3f1, Xtro\pou5f3.1, Xtro\pou1f1, Xtro\pou5f3.2, Xtro\pou6f1" "Mmus\Pou6f2, Mmus\Pou2f1, Mmus\Pou1f1, Mmus\Pou3f2, Mmus\Lmx1b, Mmus\Pou3f1, Mmus\Pou6f1, Mmus\Pou2f2, Mmus\Pou5f2, Mmus\Pou5f1, Mmus\Lmx1a, Mmus\Pou2f3, Mmus\Hoxa7, Mmus\Hoxb7, Mmus\Pou3f3, Mmus\Pou3f4" "Hsap\POU5F1B, Hsap\POU5F1, Hsap\HOXB7, Hsap\LMX1B, Hsap\POU3F4, Hsap\POU1F1, Hsap\POU2F3, Hsap\POU3F2, Hsap\LMX1A, Hsap\POU2F2, Hsap\POU6F1, Hsap\POU2F1, Hsap\POU5F2, Hsap\POU6F2, Hsap\POU3F1, Hsap\HOXA7, Hsap\POU3F3" " embryonic stage | mid , embryonic stage , oogenesis stage , embryonic stage | late , embryonic stage | < 8-12 hr , embryonic stage | <8-12 hr " " tracheal primordium

, glial cell

, mesectoderm

, ventral midline

, supraesophageal ganglion

, central nervous system | restricted

, embryonic peripheral nervous system | restricted

, neuron

, ventral nerve cord

, ectoderm

" " embryonic stage | stage 10,11 , embryonic stage | stage 13-17 , embryonic stage | stage >10 , embryonic stage | late , embryonic stage | stage 10-12 , embryonic stage | stage 10-11 , embryonic stage | stage 10 , embryonic stage | stage 13-15 , embryonic stage | stage 13-16 , embryonic stage | stage >=10 " " labral segment | restricted

, epidermis

, embryonic/larval tracheal pit

, central nervous system | restricted

, ventral midline

, labrum | restricted

, tracheal primordium

, serotonergic neuron

, embryonic/larval hindgut

, RP neuron

, abdominal 1--7 larval oenocyte group

, midline glial cell

, procephalic segment | restricted

" FBgn0002440 l(3)mbn lethal (3) malignant blood neoplasm http://flybase.org/reports/FBgn0002440 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model wing disc development ; GO:0035220 | inferred from genetic interaction with Bx chitin-based cuticle development ; GO:0040003 | inferred from sequence model chaeta development ; GO:0022416 | inferred from genetic interaction with Chi extracellular matrix ; GO:0031012 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "l(3)mbn-1, l(3)malignant blood neoplasm1, MBN, l(3)mbn1, CG12755, l(3)mbn" IPR000618:Insect cuticle protein CG12755 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage , embryonic stage && larval stage , pupal stage&&adult stage , pupal stage && adult stage " " proplasmatocyte

, embryonic/larval digestive system

, plasmatocyte

, pericardial cell

, embryonic/larval fat body

, embryonic/larval trachea

, hemolymph

, lymph gland

" "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,immune response defective,melanotic mass phenotype,viable" "melanotic mass,embryonic/larval lymph gland,plasmatocyte,podocyte,crystal cell,lamellocyte,ectopic,hemocyte" DRSC08793 I 1.654498783 0.729003592 0.283274474 0.323824116 -0.362590179 -0.162480976 FBgn0025776 ind intermediate neuroblasts defective http://flybase.org/reports/FBgn0025776 - protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with D sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" pattern specification process ; GO:0007389 | non-traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype brain development ; GO:0007420 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype ventral cord development ; GO:0007419 | non-traceable author statement central nervous system development ; GO:0007417 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | traceable author statement central nervous system development ; GO:0007417 | non-traceable author statement ventral cord development ; GO:0007419 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "CG11551, ind, Ind, ind/Gsx" "IPR011990:Tetratricopeptide-like helical domain, IPR020479:Homeobox domain, metazoa, IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG11551 11-Aug-17 DroID_v2017_08 "Drer\hoxc1a, Drer\meox2b, Drer\meox2a, Drer\meox1, Drer\gsx2, Drer\hoxb6b, Drer\hoxb8b, Drer\hoxa5a, Drer\hoxb1a, Drer\hoxc3a, Drer\hoxb2a, Drer\hoxb5b, Drer\hoxa3a, Drer\hoxc8a, Drer\hoxa4a, Drer\mnx1, Drer\hoxc4a, Drer\hoxc6a, Drer\gsx1, Drer\hoxa1a, Drer\hoxb6a, Drer\hoxb4a, Drer\mnx2a, Drer\hoxd3a, Drer\hoxc6b, Drer\gbx1, Drer\pdx1, Drer\hoxa2b, Drer\gbx2, Drer\hoxb1b, Drer\hoxb5a, Drer\hoxd4a, Drer\hoxa9b, Drer\hoxc5a, Drer\hoxb3a, Drer\hoxb7a" - "Cele\ceh-62, Cele\ceh-12, Cele\ceh-43" "Xtro\pdx1, Xtro\hoxa1, Xtro\hoxc5, Xtro\hoxd3, Xtro\meox2, Xtro\hoxb2, Xtro\hoxc3, Xtro\hoxc4, Xtro\hoxb5, Xtro\hoxb1, Xtro\gbx2.2, Xtro\mnx1, Xtro\gbx2.1, Xtro\hoxa5, Xtro\hoxb8, Xtro\hoxd1, Xtro\gsx2, Xtro\hoxd8, Xtro\hoxb7, Xtro\hoxb3, Xtro\hoxa3, Xtro\gsx1, Xtro\hoxb4, Xtro\hoxb6, Xtro\hoxc8, Xtro\hoxa2, Xtro\tlx3" "Mmus\Hoxb7, Mmus\Hoxa1, Mmus\Hoxb2, Mmus\Hoxd4, Mmus\Hoxd3, Mmus\Hoxb6, Mmus\Pdx1, Mmus\Hoxd8, Mmus\Hoxa7, Mmus\Hoxa6, Mmus\Dlx6, Mmus\Hoxd1, Mmus\Gbx2, Mmus\Mnx1, Mmus\Hoxc6, Mmus\Hoxb4, Mmus\Hoxc5, Mmus\Gbx1, Mmus\Hoxa4, Mmus\Hoxa2, Mmus\Hoxb5, Mmus\Hoxa5, Mmus\Hoxc8, Mmus\Hoxb8, Mmus\Gsx1, Mmus\Meox2, Mmus\Hoxb1, Mmus\Meox1, Mmus\Hoxc4, Mmus\Hoxa3, Mmus\Hoxb3, Mmus\Gsx2" "Hsap\HOXB8, Hsap\HOXA5, Hsap\HOXB1, Hsap\MEOX2, Hsap\HOXD1, Hsap\HOXB7, Hsap\HOXB5, Hsap\HOXA2, Hsap\HOXC5, Hsap\HOXD3, Hsap\GBX2, Hsap\GBX1, Hsap\HOXA1, Hsap\GSX2, Hsap\PDX1, Hsap\HOXB2, Hsap\HOXD4, Hsap\DLX6, Hsap\MEOX1, Hsap\HOXC8, Hsap\MNX1, Hsap\HOXB6, Hsap\HOXB3, Hsap\HOXA7, Hsap\HOXD8, Hsap\HOXA6, Hsap\HOXC6, Hsap\HOXC4, Hsap\HOXB4, Hsap\GSX1, Hsap\HOXA3, Hsap\HOXA4" " embryonic stage | stage 8 , embryonic stage | stage 9-11 , embryonic stage | stage 9 , embryonic stage | stage 5-8 , embryonic stage | 2-8 hr " " stage 1 neuroblast | subset

, neuroblast | subset

, neuroblast NB5-3

, deuterocerebral neuroblast | subset

, neuroblast NB3-2

, ventral neurogenic region && embryonic ocular segment | medial & restricted

, ventral neurogenic region | restricted

, neuroblast NB7-2

, ventral neurogenic region && embryonic antennal segment | medial & restricted

, neuroblast NB6-2

, ventral neurogenic region && embryonic intercalary segment | medial & restricted

, procephalic neuroblast | subset

, neuroblast NB4-2

, tritocerebral neuroblast | subset

, protocerebral neuroblast | subset

" " embryonic stage | stage 5-8 , embryonic stage | stage 8-13 " " ventral neurogenic region | restricted

, neuroblast | subset

" "neuroanatomy defective,viable" "neuroblast of ventral nerve cord primordium,RP2 motor neuron,intermediate ventral neurectoderm" FBgn0264403 FCG-F - http://flybase.org/reports/FBgn0264403 gene - - - FCG-F - - 11-Aug-17 DroID_v2017_08 - - - - - - "follicle cell,somatic clone" FBgn0004889 tws twins http://flybase.org/reports/FBgn0004889 "FBgn0004906, FBgn0010249, FBgn0010748, FBgn0010780, FBgn0011012, FBgn0011434, FBgn0028118, FBgn0037791, FBgn0060325, FBgn0060355, FBgn0060382, FBgn0060393, FBgn0060451, FBgn0060476, FBgn0060482, FBgn0060490, FBgn0060503, FBgn0060530, FBgn0060599, FBgn0060620, FBgn0060667, FBgn0060680, FBgn0060683, FBgn0060685, FBgn0060686, FBgn0060717, FBgn0060727, FBgn0060736, FBgn0060738, FBgn0060744, FBgn0060764, FBgn0060771, FBgn0060777, FBgn0060782, FBgn0060814, FBgn0060817, FBgn0060835, FBgn0060851, FBgn0060857, FBgn0060858, FBgn0060872, FBgn0060877, FBgn0060907, FBgn0060908, FBgn0060915, FBgn0060916, FBgn0060954, FBgn0060957, FBgn0060959, FBgn0060962, FBgn0060965, FBgn0060971, FBgn0060972, FBgn0060974, FBgn0060977, FBgn0060995, FBgn0060996, FBgn0061006, FBgn0061008, FBgn0061016, FBgn0061017, FBgn0061018, FBgn0061025, FBgn0061026, FBgn0061030, FBgn0061036, FBgn0061050, FBgn0061051, FBgn0061053, FBgn0061055, FBgn0061059, FBgn0061060, FBgn0061062" protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from mutant phenotype protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with UniProtKB:P63151 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype imaginal disc pattern formation ; GO:0007447 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from direct assay inferred from mutant phenotype regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from mutant phenotype metaphase/anaphase transition of mitotic cell cycle ; GO:0007091 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype inferred from genetic interaction with dsh inferred from genetic interaction with sgg inferred from genetic interaction with pan maintenance of neuroblast polarity ; GO:0045201 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype peptidyl-serine dephosphorylation ; GO:0070262 | inferred from biological aspect of ancestor with PANTHER:PTN000221745 embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay protein phosphatase type 2A complex ; GO:0000159 | inferred from biological aspect of ancestor with PANTHER:PTN000221745 cytosol ; GO:0005829 | inferred from direct assay protein phosphatase type 2A complex ; GO:0000159 | inferred from sequence or structural similarity protein phosphatase type 2A complex ; GO:0000159 | inferred from sequence or structural similarity with UniProtKB:P63151 "tws, CG6235, PR55, PP2A, l(3)S049902, tws/aar, aar, B/PR55, v158, 2414, l(3)02414, DPR55, tw, l(3)S061805, 1466/06, l(3)S146606, l(3)S141309, l(3)S134601a, l(3)S132907, l(3)S119908, l(3)S111515, l(3)S110815, l(3)S110008a, l(3)S105605, l(3)S101413b, l(3)S091905, l(3)S088513, l(3)S080409, l(3)S076415, l(3)S075902b, l(3)S075515b, l(3)S075110, l(3)S069206a, l(3)S067915, l(3)S067109b, l(3)S066813, l(3)S066017, l(3)S063110, l(3)S061915, l(3)S060804, l(3)S060203, l(3)S053011, l(3)S052810, l(3)S048507, l(3)S048013, l(3)S048006, l(3)S046918, l(3)S045519, l(3)S043029, l(3)S043008b, l(3)S042630, l(3)S042629, l(3)S035505b, l(3)S033903, l(3)S032708c, l(3)S032303, l(3)S031006, l(3)S029701a, l(3)S029403, l(3)S029110, l(3)S028707, l(3)S027313, l(3)S027127, l(3)S026326, l(3)S026226, l(3)S025913, l(3)S025832, l(3)S025806, l(3)S024838, l(3)S024834a, l(3)S024455, l(3)S023938, l(3)S023309, l(3)S023206, l(3)S023141a, l(3)S023013, l(3)S022440, l(3)S022361, l(3)S022205b, l(3)s1801, l(3)j11C8, l(3)01436, Pp2A-85F, dPP2A, dPR55, PP2a, Tws, PP2A[B], dPP2A-Balpha, dPP2A-B55, PP2A-B55" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR018067:Protein phosphatase 2A regulatory subunit PR55, conserved site, IPR017986:WD40-repeat-containing domain, IPR000009:Protein phosphatase 2A regulatory subunit PR55, IPR001680:WD40 repeat" CG6235 11-Aug-17 DroID_v2017_08 "Drer\ppp2r2bb, Drer\ppp2r2cb, Drer\ppp2r2aa, Drer\ppp2r2ca, Drer\ppp2r2d, Drer\ppp2r2ab, Drer\ppp2r2ba" Scer\CDC55 Cele\sur-6 "Xtro\ppp2r2a, Xtro\ppp2r2c, Xtro\ppp2r2b, Xtro\ppp2r2d" "Mmus\Ppp2r2a, Mmus\Ppp2r2b, Mmus\Ppp2r2c, Mmus\Ppp2r2d" "Hsap\PPP2R2C, Hsap\PPP2R2B, Hsap\PPP2R2D, Hsap\PPP2R2A" " pupal stage | late , embryonic stage | mid-late , adult stage && oogenesis stage , embryonic stage | late , larval stage , adult stage && oogenesis stage | stage >=S6 , pupal stage && spermatogenesis | late , embryonic stage | syncytial blastoderm , larval stage | third instar , pupal stage&&spermatogenesis | late , pupal stage && spermatogenesis " " imaginal disc

, neuroblast

, oocyte

, embryonic/larval hindgut

, eye-antennal disc

, nurse cell

, anal pad

, gonad

, optic lobe

, testis

, Malpighian tubule

, larval central nervous system

, embryonic central nervous system

, ventral thoracic disc

, dorsal mesothoracic disc

" " larval stage , embryonic stage&&larval stage&&pupal stage " " imaginal disc

, larval central nervous system

, embryonic/larval salivary gland

" "some die during larval stage,lethal - all die before end of larval stage,recessive,lethal,lethal - all die before end of prepupal stage,some die during prepupal stage,partially lethal - majority die,increased cell number,somatic clone,cell shape defective,lethal - all die before end of pupal stage,some die during pupal stage,decreased cell size,polyphasic,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,meiotic cell cycle defective,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,uncoordinated,behavior defective,some die during immature adult stage,female sterile,increased cell death,short lived,heat sensitive,neuroanatomy defective,progressive,locomotor rhythm defective,viable,visible,body color defective" "wing disc,macrochaeta,wing margin,somatic clone,mitochondrion,embryonic/larval neuroblast,supernumerary,embryonic/larval optic lobe,abdomen,maternal effect,neuroblast,mitotic cell cycle,mitotic anaphase,germarium,ovary,testis,ganglion,chromosome, centromeric region,larval brain & nuclear chromosome,posterior compartment,haltere disc,wing margin bristle,ectopic,spindle & neuroblast,mitotic anaphase & neuroblast,mitotic metaphase & neuroblast,eye,nuclear chromosome & mitotic anaphase,chromatin & mitotic anaphase,trichogen cell,tormogen cell,microchaeta,thecogen cell,eo neuron,trichome of the posterior wing margin,adult brain,progressive,mitochondrionelav.PU,mitochondrionen.PU,mesothoracic tergum" DRSC17092 E -0.887862963 -1.475691949 -2.006805725 -2.616713971 0.201475371 0.206109779 FBgn0036208 CG10361 - http://flybase.org/reports/FBgn0036208 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839 glycine C-acetyltransferase activity ; GO:0008890 | inferred from sequence or structural similarity with UniProtKB:O75600 threonine catabolic process ; GO:0006567 | inferred from electronic annotation with InterPro:IPR011282 biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004839 cellular amino acid metabolic process ; GO:0006520 | inferred from sequence or structural similarity with UniProtKB:O75600 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O75600 CG10361 "IPR001917:Aminotransferase, class-II, pyridoxal-phosphate binding site, IPR004839:Aminotransferase, class I/classII, IPR011282:2-amino-3-ketobutyrate coenzyme A ligase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG10361 11-Aug-17 DroID_v2017_08 "Drer\zgc:109965, Drer\alas1, Drer\alas2, Drer\gcat" Scer\HEM1 Cele\T25B9.1 "Xtro\ncln, Xtro\gcat, Xtro\alas2" "Mmus\Alas2, Mmus\Ncln, Mmus\Gcat, Mmus\Alas1" "Hsap\GCAT, Hsap\ALAS1, Hsap\NCLN, Hsap\ALAS2" "viable,fertile" FBgn0261797 Dhc64C Dynein heavy chain 64C http://flybase.org/reports/FBgn0261797 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule motor activity ; GO:0003777 | inferred from direct assay dynein light intermediate chain binding ; GO:0051959 | inferred from sequence or structural similarity with UniProtKB:Q14204 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATPase activity, coupled ; GO:0042623 | inferred from direct assay dynein intermediate chain binding ; GO:0045505 | inferred from sequence or structural similarity with UniProtKB:P34036" centrosome localization ; GO:0051642 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype protein localization to kinetochore ; GO:0034501 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity mitochondrion distribution ; GO:0048311 | inferred from mutant phenotype stress granule assembly ; GO:0034063 | inferred from mutant phenotype germ-line cyst formation ; GO:0048134 | traceable author statement maintenance of RNA location ; GO:0051237 | inferred from direct assay retrograde axonal transport ; GO:0008090 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from genetic interaction with sdt fusome organization ; GO:0045478 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype RNA transport ; GO:0050658 | inferred from mutant phenotype mitochondrion transport along microtubule ; GO:0047497 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype oocyte nucleus migration involved in oocyte dorsal/ventral axis specification ; GO:0007312 | traceable author statement cellularization ; GO:0007349 | inferred from mutant phenotype establishment of Golgi localization ; GO:0051683 | inferred from mutant phenotype establishment of mitotic spindle localization ; GO:0040001 | traceable author statement ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype centrosome cycle ; GO:0007098 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype cystoblast division ; GO:0007282 | inferred from mutant phenotype positive regulation of neuron remodeling ; GO:1904801 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | traceable author statement regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from direct assay establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from direct assay positive regulation of mitotic centrosome separation ; GO:0046604 | inferred from mutant phenotype dynein complex ; GO:0030286 | inferred from physical interaction with Dlic mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay fusome ; GO:0045169 | traceable author statement intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay cytoplasmic dynein complex ; GO:0005868 | inferred from sequence or structural similarity cytoplasmic dynein complex ; GO:0005868 | inferred from sequence or structural similarity with UniProtKB:P36022 microtubule associated complex ; GO:0005875 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "DYHC, Dhc64C, Dhc, CG7507, DHC, dhc64C, dhc, Dhc64, Dhc64c, cDhc, DHC64C, CD, cDhc64C, Cdhc, Fs(3)Lab, HMW MAP, Lab, Fs(3)Laborc, l(3)64Ca, Fs(3)Sz18, Dynein, Su(Gl)77, FCP-A, Dhc46C, dhc64c, DHC1" "IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003593:AAA+ ATPase domain, IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2" CG7507 11-Aug-17 DroID_v2017_08 "Drer\dnah7l, Drer\si:dkeyp-87a6.1, Drer\dync1h1, Drer\wu:fj30b09, Drer\si:dkeyp-86b9.1, Drer\dnah3, Drer\dnah1, Drer\dnah12, Drer\dnah2, Drer\dnah7, Drer\dnah9l" Scer\DYN1 "Cele\che-3, Cele\W05B2.7, Cele\dhc-1" "Xtro\dnah2, Xtro\dnah7, Xtro\dnah14" "Mmus\Dnah5, Mmus\Dnah7a, Mmus\Dnah9, Mmus\Dnah7b, Mmus\Dnhd1, Mmus\Dnah8, Mmus\Dnah12, Mmus\Dync1h1, Mmus\Dnah10, Mmus\Dnah11, Mmus\Dnah17, Mmus\Dnah2, Mmus\Dnah3, Mmus\Dync2h1, Mmus\Dnah1, Mmus\Dnah6" "Hsap\DNAH3, Hsap\DNAH17, Hsap\DNAH8, Hsap\DNAH7, Hsap\DYNC1H1, Hsap\DNAH14, Hsap\DNAH2, Hsap\DNAH5, Hsap\DNAH9, Hsap\DYNC2H1, Hsap\DNAH6, Hsap\DNHD1, Hsap\DNAH1, Hsap\CCDC88B, Hsap\DNAH10, Hsap\DNAH11, Hsap\DNAH12" " adult stage | male , adult stage | female , embryonic stage " " ovary

, testis

" stage S10A oocyte

posterior FBgn0004838 Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C http://flybase.org/reports/FBgn0004838 "FBgn0010261, FBgn0016665, FBgn0019729, FBgn0024845, FBgn0061493" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with glo mRNA 5'-UTR binding ; GO:0048027 | traceable author statement mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay single-stranded DNA binding ; GO:0003697 | inferred from direct assay mRNA 5'-UTR binding ; GO:0048027 | non-traceable author statement mRNA 3'-UTR binding ; GO:0003730 | traceable author statement mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype negative regulation of oskar mRNA translation ; GO:0007319 | traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of mRNA splicing, via spliceosome ; GO:0048024 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from sequence or structural similarity with HGNC:5031 inferred from direct assay inferred from physical interaction with sqd cytoplasm ; GO:0005737 | inferred from direct assay P granule ; GO:0043186 | inferred from physical interaction with tud inferred from physical interaction with vas protein complex ; GO:0043234 | inferred from physical interaction with glo nucleolus ; GO:0005730 | NOT inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "Hrb27c, Hrp48, hrp48, p50, Hrb48, hrb27C, CG10377, hnRNP27C, RRM7, 10280, l(2)02647, l(2)2647, l(2)10280, rrm7, linha, Rbp7, Hrb27C, Hrb27-C, hnRNP48, HRB27C, hrb27c, Ov5, HRP48, Hrp48/Hrb27C, hrb27" "IPR000504:RNA recognition motif domain, IPR034134:DAZ-associated protein 1, RNA recognition motif 1, IPR034131:DAZ-associated protein 1, RNA recognition motif 2" CG10377 11-Aug-17 DroID_v2017_08 "Drer\hnrnpa0b, Drer\dazap1, Drer\msi2a, Drer\zgc:110796, Drer\hnrnpaba, Drer\hnrnpa1b, Drer\hnrnpabb, Drer\hnrpdl, Drer\hnrnpa0a, Drer\hnrnpa0l, Drer\msi2b, Drer\hnrnpa3, Drer\hnrnpa1a, Drer\msi1, Drer\hnrnpd" Scer\HRP1 "Cele\rsp-1, Cele\H28G03.1, Cele\hrp-1, Cele\msi-1" "Xtro\hnrnpa1, Xtro\dazap1, Xtro\msi1, Xtro\hnrnpd, Xtro\hnrnpdl, Xtro\hnrnpa3, Xtro\hnrnpa2b1, Xtro\hnrnpab, Xtro\hnrnpa0" "Mmus\Hnrnpd, Mmus\Dazap1, Mmus\Hnrnpa2b1, Mmus\Hnrnpa0, Mmus\Hnrnpdl, Mmus\Msi2, Mmus\Msi1, Mmus\Hnrnpab, Mmus\Hnrnpa3, Mmus\Hnrnpa1, Mmus\Rbm31y" "Hsap\HNRNPA3, Hsap\HNRNPA0, Hsap\HNRNPA2B1, Hsap\HNRNPA1L2, Hsap\HNRNPAB, Hsap\MSI2, Hsap\DAZAP1, Hsap\HNRNPD, Hsap\HNRNPA1, Hsap\HNRNPDL, Hsap\MSI1" " oogenesis stage && adult stage | female , embryonic stage -- adult stage , embryonic stage | early " ovary

"neuroanatomy defective,somatic clone,viable,visible,partially lethal - majority die,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,female semi-sterile,germline clone,female sterile,some die during pupal stage" "border follicle cell,somatic clone,egg,chorion,nurse cell & nuclear chromosome,wing margin,oocyte & cytoskeleton | germ-line clone,ommatidium,female,posterior supraalar bristle,germline clone,dorsal appendage,egg operculum,chorion | germline clone,ovary,scutellar bristle,trichogen cell,embryonic/larval hemocyte | third instar larval stage,egg chamber,chaeta,supernumerary,mesothoracic tergum" DRSC03347 K -0.027526998 -1.397433038 0.216716041 0.160620442 -2.080069608 0.689284651 FBgn0005596 yem yemanuclein http://flybase.org/reports/FBgn0005596 "FBgn0004042, FBgn0040620" protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay "fertilization, exchange of chromosomal proteins ; GO:0035042 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype" germinal vesicle ; GO:0042585 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay male pronucleus ; GO:0001940 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay "yem-alpha, yema, yG4.5, yT4.5, CG11879, CG14513, yemalpha, yem, Yemalpha" "IPR014840:Hpc2-related domain, IPR026947:Ubinuclein middle domain" CG14513 11-Aug-17 DroID_v2017_08 "Drer\ubn2b, Drer\ubn1, Drer\ubn2a" - - "Xtro\ubn1, Xtro\ttc26" "Mmus\Ubn2, Mmus\Ubn1" "Hsap\UBN2, Hsap\UBN1" " adult stage && oogenesis stage | stage <=S7 , embryonic stage | stage <6 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S7 , adult stage && oogenesis stage | stage >=S10B , embryonic stage | stage <=8 , adult stage && oogenesis stage | stage S8-10A " " oocyte | posterior

, organism

, germarium region 2

, oocyte

, ovary

, oocyte | anterior

" "female sterile,lethal - all die during embryonic stage,maternal effect,partially lethal,viable,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "male pronucleus | maternal effect3450),oocyte" FBgn0003460 so sine oculis http://flybase.org/reports/FBgn0003460 "FBgn0004392, FBgn0004874" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with fl(2)d sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Sobp transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with ey transcription factor binding ; GO:0008134 | inferred from physical interaction with eya inferred from physical interaction with gro" eye-antennal disc morphogenesis ; GO:0007455 | traceable author statement Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype ring gland development ; GO:0035271 | inferred from mutant phenotype entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from genetic interaction with mnb optic lobe placode formation ; GO:0001744 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "So, somda, Drl, mda, old, med, ami, CG11121, so, SO, sine oculis, Sine oculis" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR031701:Homeobox protein SIX1, N-terminal SD domain" CG11121 11-Aug-17 DroID_v2017_08 "Drer\six2b, Drer\six1a, Drer\six3b, Drer\six3a, Drer\six2a, Drer\six5, Drer\six9, Drer\six4b, Drer\six6a, Drer\six7, Drer\six1b, Drer\six6b" Scer\PHO2 "Cele\ceh-34, Cele\ceh-33, Cele\ceh-32" "Xtro\six3, Xtro\six2, Xtro\six4, Xtro\six1, Xtro\six6" "Mmus\Six3, Mmus\Six2, Mmus\Six6, Mmus\Six1, Mmus\Six5, Mmus\Six4" "Hsap\SIX3, Hsap\SIX1, Hsap\SIX2, Hsap\ANHX, Hsap\SIX6, Hsap\SIX4, Hsap\SIX5" " embryonic stage | stage 12 , larval stage | third instar , embryonic stage | stage 9 , embryonic stage , embryonic stage | stage 16 " " epidermis

, eye disc

, optic lobe | presumptive

, embryonic optic lobe primordium

, Bolwig's organ

" " larval stage | third instar , embryonic stage , adult stage | male , adult stage , embryonic stage | stage 9 , embryonic stage | stage 12 , embryonic stage | stage 16 " " eye disc

, embryonic optic lobe primordium

, photoreceptor cell R1--7

, cyst cell

, eye-antennal disc

, optic lobe | presumptive

, ocellus

, epidermis

, Bolwig's organ

, optic lobe

" "visible,viable,fertile,male,neuroanatomy defective,behavior defective,recessive,phototaxis defective,visual behavior defective,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,dominant,lethal - all die before end of first instar larval stage,some die during first instar larval stage,increased cell death,cell growth defective,somatic clone,circadian rhythm defective,partially lethal - majority live,size defective" "optic lobe,cell body rind of medulla,lobula,eye,optic chiasma,lamina,medulla,photoreceptor cell,precursor,neuroblast & embryonic optic lobe primordium,P5m fiber tract founder cluster,ocellus,visual primordium,Bolwig organ,eye disc & neuron,larval LN period neuron,ectopic,antenna,adult head,wing,eye disc,heat sensitive,glial cell & larval optic lobe,medulla neuropil,ommatidium,lamina & neuron,lamina anlage glial cell,cuticle,somatic clone,subretinal glial cell,morphogenetic furrow,Pdf neuron,retina,eye photoreceptor cell,embryonic/larval optic stalk,embryonic stomatogastric nervous system,photoreceptor cell R1,photoreceptor cell R6,photoreceptor cell R7,interfollicle cell,cell non-autonomous,embryonic/larval stomatogastric nervous system,corpus cardiacum primordium,medial ocellus" FBgn0010051 Itp-r83A "Inositol 1,4,5,-tris-phosphate receptor" http://flybase.org/reports/FBgn0010051 "FBgn0010234, FBgn0010870, FBgn0011378, FBgn0023199, FBgn0066011" protein_coding_gene "inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity ; GO:0005220 | inferred from direct assay calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN001416417" "salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | inferred from direct assay fatty acid homeostasis ; GO:0055089 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype molting cycle, chitin-based cuticle ; GO:0007591 | inferred from genetic interaction with rut regulation of feeding behavior ; GO:0060259 | inferred from mutant phenotype release of sequestered calcium ion into cytosol ; GO:0051209 | inferred from mutant phenotype positive regulation of ecdysteroid secretion ; GO:0046000 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype nuclear division ; GO:0000280 | inferred from direct assay cellular calcium ion homeostasis ; GO:0006874 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | inferred from mutant phenotype stabilization of membrane potential ; GO:0030322 | inferred from genetic interaction with Gαq positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway ; GO:0051482 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001416417 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "itpr, IP3R, IP[[3]]R, DmInsP[[3]]R, DmInsP[[3R]], InsP[[3]]R, dip, IP[[3]] receptor, CG1063, Itp-r[1], InsP[[3]], l(3)05616, DIP, l(3)j5B4, Itp-r42B, Itp-r, Insp3R, IP, anon-WO02059370.49, Itp-r83A, Ins3PR, Itpr, Itp-r-83A, dIP[[3]]R, l(3)itpr, itpr-83, ITP-r83A, Ip3R, ITPR1" "IPR000493:Inositol 1,4,5-trisphosphate-binding protein receptor, IPR000699:RIH (RyR and IP3R Homology) domain, IPR005821:Ion transport domain, IPR013662:RyR/IP3R Homology associated domain, IPR015925:Ryanodine receptor-related, IPR014821:Inositol 1,4,5-trisphosphate/ryanodine receptor, IPR016093:MIR motif" CG1063 11-Aug-17 DroID_v2017_08 "Drer\itpr3, Drer\itpr1a, Drer\itpr2, Drer\itpr1b" - Cele\itr-1 "Xtro\itpr3, Xtro\itpr1, Xtro\itpr2" "Mmus\Itpr2, Mmus\Itpr3, Mmus\Itpr1" "Hsap\ITPR1, Hsap\ITPR3, Hsap\ITPR2" " embryonic stage | stage 14 , adult stage , embryonic stage | stage 15 , embryonic stage , embryonic stage | stage 13 , embryonic stage | early " " labral segment

, eye

, head | anterior

, labial organ

, epidermis | lateral

, adult brain

, leg

, antenna

" " adult stage , larval stage | third instar , embryonic stage | stage 13 , pupal stage , embryonic stage | stage 9 , pupal stage | late , embryonic stage | stage >=9 " " antennal segment 3 sensillum

, photoreceptor cell

, ring gland

, antennal segment 2 sensillum

, somatic mesoderm

, dorsal medial muscle

, myoblast &&of ventral thoracic disc

, morphogenetic furrow | posterior to

, pigment cell

, eye disc

, olfactory sensory organ

, antenna

, mesoderm

, second antennal segment muscle

, embryonic/larval salivary gland

, pharyngeal muscle

, maxillary palp sense organ

, cone cell

, myoblast

, proboscis

, head mesoderm

, myoblast &&of dorsal mesothoracic disc

, cardioblast

, adult brain

, visceral mesoderm

, myoblast &&of imaginal disc

" "feeding behavior defective,lethal - all die before end of larval stage,some die during larval stage,recessive,lethal - all die before end of pupal stage,some die during pupal stage,developmental rate defective,lethal,viable,chemical resistant,dominant,wild-type,cold sensitive,flightless,fertile,poor,starvation stress response defective,large body,gravitaxis defective,visible,neurophysiology defective,partially,flight defective,body size defective,maternal effect,body color defective,neuroanatomy defective,partially lethal - majority die,some die during P-stage,some die during third instar larval stage" "interommatidial bristle,somatic clone,eye photoreceptor cell,rhabdomere,wing,indirect flight muscle,dorsal medial muscle,wing margin,embryonic/larval fat body,midgut primordium,maternal effect,principal midgut epithelial cell,embryonic/larval salivary gland,imaginal disc,neuroblast,ommatidium,mesothoracic tergum,adult mushroom body,antennal lobe" FBgn0000575 emc extra macrochaetae http://flybase.org/reports/FBgn0000575 "FBgn0010839, FBgn0010869, FBgn0011251, FBgn0011371, FBgn0013464" protein_coding_gene "transcriptional repressor activity, RNA polymerase II transcription factor binding ; GO:0001191 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ac inferred from physical interaction with l(1)sc inferred from physical interaction with sc inferred from physical interaction with da" "compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype photoreceptor cell fate commitment ; GO:0046552 | inferred from mutant phenotype sex determination ; GO:0007530 | inferred from genetic interaction with dpn, Sxl inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype progression of morphogenetic furrow involved in compound eye morphogenesis ; GO:0007458 | inferred from mutant phenotype sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inferred from genetic interaction with Egfr inferred from genetic interaction with vn spermatid development ; GO:0007286 | inferred from mutant phenotype chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype R3/R4 cell differentiation ; GO:0048056 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement cell proliferation ; GO:0008283 | inferred from mutant phenotype inferred from genetic interaction with Egfr inferred from genetic interaction with vn startle response ; GO:0001964 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | traceable author statement dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype inferred from genetic interaction with net inferred from genetic interaction with px inferred from genetic interaction with bs midgut development ; GO:0007494 | inferred from mutant phenotype R8 cell fate commitment ; GO:0007460 | non-traceable author statement negative regulation of DNA binding ; GO:0043392 | inferred from direct assay dorsal closure ; GO:0007391 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR026052 nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Emc, CG1007, l(3)05592, Dm0688, 0977/09, 0587/01, 0203/10, 0094/26, gov, ms(3)61CD, Ach, l(3)j4E11, l(3)04322, emc, l(3)61Da, bHLHb28" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR026052:DNA-binding protein inhibitor" CG1007 11-Aug-17 DroID_v2017_08 "Drer\id4, Drer\id2a, Drer\id3, Drer\id2b, Drer\id1" - - "Xtro\id3, Xtro\id2, Xtro\id4" "Mmus\Id3, Mmus\Id2, Mmus\Id1, Mmus\Id4" "Hsap\ID3, Hsap\ID4, Hsap\ID2, Hsap\ID1" " embryonic stage | stage 5-9 , embryonic stage | stage 13-15 , embryonic stage | stage 8 , larval stage | third instar , embryonic stage | stage 7 , embryonic stage | stage 15 , embryonic stage | stage 8-10 , embryonic stage | stage 11-13 , embryonic stage | stage 6 , embryonic stage | stage 5 , embryonic stage | stage 10 , embryonic stage | stage 11 , embryonic stage -- adult stage , embryonic stage | stage 6,7 , egg stage | unfertilized egg , embryonic stage | stage 13 , embryonic stage " " embryonic/larval hindgut

, visceral mesoderm

, mesoderm

,

ubiquitous , anterior midgut proper primordium

, central nervous system

, posterior midgut proper primordium

, embryonic/larval foregut

, cephalic furrow

, embryonic optic lobe primordium

, Malpighian tubule

, inclusive hindgut primordium

, anterior embryonic/larval midgut

,

stripes , tracheal pit

, posterior embryonic/larval midgut

, amnioserosa

, amnioproctodeal invagination

, tracheal pit | presumptive

, posterior transverse furrow

, epidermis | segmentally repeated

, unfertilized egg

, proctodeum

, ventral nerve cord

, apodeme

, ventral furrow

, procephalic segment

,

10% egg length , ectoderm | dorsal

, Malpighian tubule primordium

, ventral midline | restricted

, supraesophageal ganglion

, dorsal mesothoracic disc | restricted

, stomodeum

, imaginal disc

, anterior transverse furrow

" "visible,viable,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,male sterile,recessive,stress response defective,behavior defective,partially lethal - majority die,dominant,cell lethalcell lethal,somatic clone,decreased cell number,some die during pupal stage" "sense organ,ectopic,macrochaeta & thorax,dorsal appendage,chorion,egg chamber,interommatidial bristle,somatic clone,macrochaeta,supernumerary,microchaeta & mesothoracic tergum | supernumerary,embryonic/larval midgut primordium,embryonic head,dorsal fold,embryonic dorsal epidermis,microchaeta,posterior scutellar bristle,sensory mother cell,wing,dorsocentral bristle,scutellar bristle,scutellum & microchaeta-537.4,tormogen cell,eye,polar follicle cell,anterior,oocyte,eye disc,eye disc anterior to the morphogenetic furrow,photoreceptor cell R2,photoreceptor cell R8,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,leg disc anterior compartment,external sensory organ precursor cell,leg sensillum,postvertical bristle,ocellar bristle,wing vein L5,filzkorper,denticle belt,denticle row 1 & abdominal 1 ventral denticle belt,denticle row 1 & abdominal 2 ventral denticle belt,denticle row 1 & abdominal 3 ventral denticle belt,denticle row 1 & abdominal 4 ventral denticle belt,denticle row 1 & abdominal 5 ventral denticle belt,denticle row 1 & abdominal 6 ventral denticle belt,denticle row 1 & abdominal 7 ventral denticle belt,denticle row 2 & abdominal 1 ventral denticle belt,denticle row 2 & abdominal 2 ventral denticle belt,denticle row 2 & abdominal 3 ventral denticle belt,denticle row 2 & abdominal 4 ventral denticle belt,denticle row 2 & abdominal 5 ventral denticle belt,denticle row 2 & abdominal 6 ventral denticle belt,denticle row 2 & abdominal 7 ventral denticle belt,axon | embryonic stage,longitudinal connective,external sensory organ,Malpighian tubule,Malpighian tubule tip cell,embryonic/larval somatic muscle,midgut constriction 1,midgut constriction 2,midgut constriction 3,visceral mesoderm,endoderm,mesothoracic tergum,cephalopharyngeal skeleton,mesothoracic tergum & macrochaeta,embryonic/larval midgut,morphogenetic furrow,cone cell,photoreceptor cell R7,photoreceptor cell R1,photoreceptor cell R6,ommatidium,neuron,wing vein,leg,haltere,segment,antennal segment 3 sensillum,chaeta" FBgn0013759 CASK CASK http://flybase.org/reports/FBgn0013759 "FBgn0015923, FBgn0038904, FBgn0043003" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719 neurexin family protein binding ; GO:0042043 | inferred from physical interaction with UniProtKB:Q9VCZ9 protein binding ; GO:0005515 | inferred from physical interaction with Nrx-1" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 long-term memory ; GO:0007616 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from direct assay positive regulation of synaptic vesicle endocytosis ; GO:1900244 | inferred from mutant phenotype inferred from genetic interaction with Nrx-1 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement medium-term memory ; GO:0072375 | inferred from mutant phenotype regulation of locomotion ; GO:0040012 | inferred from mutant phenotype inferred from genetic interaction with Nrx-1 locomotion ; GO:0040011 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from mutant phenotype inferred from genetic interaction with Nrx-1 synaptic vesicle targeting ; GO:0016080 | non-traceable author statement synaptic vesicle docking ; GO:0016081 | non-traceable author statement anesthesia-resistant memory ; GO:0007615 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement male courtship behavior ; GO:0008049 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype" neuromuscular junction ; GO:0031594 | inferred from direct assay type I terminal bouton ; GO:0061174 | inferred from direct assay "DLin-2, caki, Cmg, cmg, CAKI, CMG/CASK, CG6703, CG13412, CG13413, CASK, CamGUK, Cask, Camguk, CMG, cask, Caki, CamguK, dCASK, CAMGUK, camguk, RE09582p, CASK-beta" "IPR000719:Protein kinase domain, IPR001452:SH3 domain, IPR001478:PDZ domain, IPR004172:L27 domain, IPR008144:Guanylate kinase-like domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR011009:Protein kinase-like domain, IPR011511:Variant SH3 domain, IPR014775:L27 domain, C-terminal, IPR020590:Guanylate kinase, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG6703 11-Aug-17 DroID_v2017_08 "Drer\mpp5b, Drer\mpp7b, Drer\caskb, Drer\camk2d1, Drer\mpp6b, Drer\mpp4a, Drer\si:ch73-272h16.4, Drer\mpp3a, Drer\camk2g1, Drer\mpp1, Drer\camk2d2, Drer\caska, Drer\mpp5a, Drer\mpp7a, Drer\camk2b, Drer\mpp3b, Drer\mpp2b, Drer\mpp6a, Drer\camk2g2, Drer\camk2b1, Drer\mpp2a, Drer\LOC556594" - "Cele\magu-3, Cele\lin-2, Cele\magu-2, Cele\magu-1" "Xtro\camk2d, Xtro\mpp1, Xtro\camk2a, Xtro\mpp7, Xtro\mpp6, Xtro\camk2g, Xtro\camk2b, Xtro\mpp5, Xtro\mpp2, Xtro\cask" "Mmus\Mpp6, Mmus\Camk2d, Mmus\Mpp1, Mmus\Mpp7, Mmus\Camk2b, Mmus\Mpp4, Mmus\Cask, Mmus\Mpp3, Mmus\Mpp2, Mmus\Mpp5, Mmus\Camk2a, Mmus\Camk2g" "Hsap\CASK, Hsap\MPP5, Hsap\CAMK2A, Hsap\MPP1, Hsap\MPP7, Hsap\CAMK2G, Hsap\MPP6, Hsap\MPP4, Hsap\MPP3, Hsap\CAMK2B, Hsap\CAMK2D, Hsap\MPP2" " adult stage && oogenesis stage | stage S10B , embryonic stage | stage 11 , embryonic stage | stage 14 , embryonic stage | stage 8-12 , pupal stage , oogenesis stage && adult stage | female , adult stage && oogenesis stage , adult stage , embryonic stage | stage >=9 , embryonic stage | 8-24 hr , larval stage , embryonic stage " " polar follicle cell

, neuroblast

, Malpighian tubule

, embryonic/larval hindgut

, anterior midgut proper primordium

, central nervous system

, posterior midgut proper primordium

, ovary

, nurse cell

, adult head

, embryonic central nervous system | presumptive | restricted

, larval central nervous system

" adult stage " lobula

, adult brain

, lobula plate

, optic lobe

, lamina

, medulla neuropil

" "fertile,courtship behavior defective,male,locomotor behavior defective,recessive,dominant,neuroanatomy defective,learning defective,memory defective,neurophysiology defective,flight defective,visual behavior defective,viable,visible" "type Ib terminal bouton | third instar larval stage,type Is terminal bouton | third instar larval stage,type Ib terminal bouton | third instar larval stageVGlut-OK371,type Ib terminal bouton | third instar larval stageMef2.PR,synaptic vesicle,embryonic/larval neuromuscular junction,bouton,chaeta,trichogen cell,border follicle cell" FBgn0041096 rols rolling pebbles http://flybase.org/reports/FBgn0041096 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 cell adhesion molecule binding ; GO:0050839 | inferred from physical interaction with kirre structural constituent of muscle ; GO:0008307 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with mbc inferred from physical interaction with kirre protein binding ; GO:0005515 | inferred from physical interaction with Actn inferred from physical interaction with blow inferred from physical interaction with zormin myoblast fusion ; GO:0007520 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from direct assay inferred from mutant phenotype myoblast fusion ; GO:0007520 | traceable author statement anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype Z disc ; GO:0030018 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay "Rols7, Ants, ANTS, Rol/Ants, rols\ants, ants, CG17155, l(3)08232, l(3)68Fd, l(3)j2A6, CG5679, CG12277, CG32096, anon-WO0257455.19, rols, Rols, ants/rols, Rols6" "IPR001841:Zinc finger, RING-type, IPR002110:Ankyrin repeat, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020683:Ankyrin repeat-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR019734:Tetratricopeptide repeat" CG32096 11-Aug-17 DroID_v2017_08 "Drer\ankrd46a, Drer\tanc1a, Drer\tanc2a, Drer\tanc1b, Drer\ankrd46b, Drer\cttnbp2, Drer\tanc2b, Drer\si:ch211-223a10.1" - - "Xtro\tanc1, Xtro\tanc2" "Mmus\Ankrd65, Mmus\Tanc2, Mmus\Ankrd46, Mmus\Tanc1, Mmus\Ankrd63, Mmus\Cttnbp2, Mmus\Ankrd50" "Hsap\TANC1, Hsap\ANKRD65, Hsap\TANC2, Hsap\ANKRD46, Hsap\CTTNBP2, Hsap\ANKRD63" " embryonic stage | stage 15 , embryonic stage | stage 12-15 , embryonic stage | stage > 12 , embryonic stage | stage 11 , embryonic stage | stage 11-14 " " muscle attachment site

, myotube

, endoderm

, embryonic muscle system && myoblast | subset

, embryonic muscle system | restricted

" " embryonic stage | stage 11-14 , embryonic stage | stage 15 , embryonic stage | stage 11 , embryonic stage | stage 12-15 " " embryonic muscle system | restricted

, muscle attachment site

, embryonic muscle system && myoblast | subset

, myotube

" "partially lethal - majority live,fertile,viable,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal" "Malpighian tubule main body primordium,embryonic Malpighian tubule,embryonic anterior Malpighian tubule,dorsal acute muscle & myotube,embryonic myoblast,embryonic somatic muscle,embryonic/larval pharynx,presumptive embryonic/larval muscle system,A1-7 dorsal acute muscle 1,presumptive embryonic/larval digestive system,muscle fiber,midgut constriction 1,border follicle cell,somatic clone" DRSC09873 IE -1.981272366 -1.159407617 -1.844324834 2.221281031 0.538576568 0.883104833 FBgn0000439 Dfd Deformed http://flybase.org/reports/FBgn0000439 - protein_coding_gene "activating transcription factor binding ; GO:0033613 | inferred from physical interaction with exd RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay positive regulation of apoptotic process involved in morphogenesis ; GO:1902339 | inferred from mutant phenotype inferred from genetic interaction with Diap1 head development ; GO:0060322 | inferred from mutant phenotype embryonic brain development ; GO:1990403 | inferred from mutant phenotype posterior head segmentation ; GO:0035289 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay regulation of gene expression ; GO:0010468 | inferred from mutant phenotype specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype head morphogenesis ; GO:0060323 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Dfd, DmDfd, dfd, EbR11, l(3)84Ae, CG2189, BG:DS00276.5, DFD" "IPR017970:Homeobox, conserved site, IPR017995:Homeobox protein, antennapedia type, IPR001356:Homeobox domain, IPR001827:Homeobox protein, antennapedia type, conserved site, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG2189 11-Aug-17 DroID_v2017_08 "Drer\mnx1, Drer\hoxb5b, Drer\hoxb6b, Drer\hoxc6b, Drer\hoxa3a, Drer\pdx1, Drer\hoxa1a, Drer\hoxc5a, Drer\mnx2a, Drer\hoxb1b, Drer\hoxa5a, Drer\gbx1, Drer\hoxb4a, Drer\meox2b, Drer\hoxc3a, Drer\hoxa2b, Drer\hoxb5a, Drer\hoxb7a, Drer\hoxc6a, Drer\hoxc1a, Drer\gsx2, Drer\meox1, Drer\hoxb3a, Drer\hoxb8b, Drer\hoxc8a, Drer\hoxd3a, Drer\hoxa9b, Drer\hoxb6a, Drer\hoxc4a, Drer\gbx2, Drer\meox2a, Drer\hoxd4a, Drer\hoxb1a, Drer\hoxa4a, Drer\gsx1, Drer\hoxb2a" "Scer\YHP1, Scer\PHO2, Scer\YOX1" "Cele\lin-39, Cele\mab-5" "Xtro\hoxc5, Xtro\hoxd3, Xtro\hoxb4, Xtro\hoxa2, Xtro\hoxa5, Xtro\hoxa1, Xtro\hoxc4, Xtro\hoxb5, Xtro\hoxd8, Xtro\gsx1, Xtro\hoxc8, Xtro\hoxb3, Xtro\gbx2.2, Xtro\gsx2, Xtro\gbx2.1, Xtro\pdx1, Xtro\hoxb1, Xtro\hoxb7, Xtro\mnx1, Xtro\hoxd1, Xtro\hoxa3, Xtro\meox2, Xtro\hoxc3, Xtro\hoxb6, Xtro\hoxb2, Xtro\hoxb8" "Mmus\Hoxd8, Mmus\Gsx1, Mmus\Hoxb5, Mmus\Hoxa7, Mmus\Hoxd4, Mmus\Hoxc4, Mmus\Gbx2, Mmus\Hoxb6, Mmus\Mnx1, Mmus\Hoxb7, Mmus\Hoxd1, Mmus\Hoxb2, Mmus\Hoxa4, Mmus\Pdx1, Mmus\Hoxb4, Mmus\Hoxb8, Mmus\Meox1, Mmus\Gsx2, Mmus\Hoxc8, Mmus\Hoxa1, Mmus\Hoxa3, Mmus\Meox2, Mmus\Hoxa2, Mmus\Hoxb1, Mmus\Hoxc5, Mmus\Hoxc6, Mmus\Gbx1, Mmus\Hoxb3, Mmus\Hoxa5, Mmus\Hoxd3, Mmus\Hoxa6" "Hsap\HOXC8, Hsap\HOXC6, Hsap\HOXD4, Hsap\MNX1, Hsap\HOXD1, Hsap\HOXC5, Hsap\HOXB6, Hsap\HOXB4, Hsap\HOXB2, Hsap\HOXD3, Hsap\HOXA5, Hsap\HOXB5, Hsap\GBX2, Hsap\GSX1, Hsap\MEOX1, Hsap\MEOX2, Hsap\HOXB7, Hsap\HOXA1, Hsap\HOXB1, Hsap\HOXB3, Hsap\HOXC4, Hsap\HOXA3, Hsap\HOXD8, Hsap\PDX1, Hsap\LHX2, Hsap\HOXA4, Hsap\HOXA6, Hsap\HOXA2, Hsap\HOXA7, Hsap\GBX1, Hsap\GSX2, Hsap\HOXB8" " embryonic stage , larval stage , embryonic stage | stage 5-9 , embryonic stage | stage 11-17 , embryonic stage | stage 5 " " prothoracic segment | posterior

, labial segment | posterior

{ + Scr*, tsh- } , larval central nervous system

, parasegment 1

, maxillary palpus | primordium

, embryonic central nervous system | restricted

, embryonic maxillary segment

, embryonic mandibular segment

, eye-antennal disc

, organism | 60-80% egg length

, parasegment 1 | anterior to

, peripodial epithelium

" " embryonic stage | stage 13 , embryonic stage , embryonic stage | stage 6 , embryonic stage | stage 7 , embryonic stage | cellular blastoderm , embryonic stage | stage >=11 , embryonic stage | stage 8 " " dorsal ridge | anterior

, parasegment 1

, cephalic furrow

, maxillary segment

, mandibular segment | ventral

, ectoderm | restricted

, mandibular segment

, ventral midline

, hypopharyngeal lobe

, maxillary segment | ventral

" "some die during embryonic stage,recessive,visible,dominant,viable,lethal,heat sensitive,poor,polyphasic,partially lethal - majority die,lethal - all die before end of embryonic stage,decreased cell death,cell shape defective,increased cell death" "head bristle,ectopic,adult head,maxillary palpus,eye,ocellus,subesophageal ganglion,heat sensitive,thoracico-abdominal ganglion,adult salivary gland,lateral process,pharyngeal bars,labial segment,prothoracic segment,mesothoracic segment,metathoracic segment,external sensory organ,labial disc,embryonic/larval labial organ,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,mouth hooks,cirri,proboscis muscle 1,embryonic maxillary segment,embryonic mandibular segment,mandibular neuromere,hypostomal sclerite,dental sclerite,terminal organ,ventral organ,embryonic head,cephalopharyngeal skeleton,posterior,embryonic tritocerebrum,ectopic | embryonic stage,embryonic thoracic segment & embryonic/first instar larval cuticleprd.RG1,abdominal segment & embryonic/first instar larval cuticleprd.RG1,abdominal lateral monoscolopidial chordotonal organ lch1 | embryonic stage,abdominal ventral monoscolopidial chordotonal organ vch1 | embryonic stage,dorsal group sensillum | embryonic stage,intersegmental nerve,segmental nerve,presumptive embryonic/larval tracheal system,dorsal ridge,embryonic/larval oenocyte precursor,embryonic gastric caecum & parasegment 3how-24B,embryonic head segment,embryonic abdominal segment,embryonic labial segment,embryonic thoracic segment,third segment of antenna,antennal disc,arista,pretarsus,embryonic segment,embryonic/first instar larval cuticle,denticle" FBgn0024245 dnt doughnut on 2 http://flybase.org/reports/FBgn0024245 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein tyrosine kinase activity ; GO:0004713 | NOT inferred from key residues protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with drl inferred from physical interaction with Drl-2 "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR020635 lateral inhibition ; GO:0046331 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype determination of muscle attachment site ; GO:0016204 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity receptor complex ; GO:0043235 | inferred from direct assay "CG17559, dnt, DNT" "IPR000719:Protein kinase domain, IPR003306:WIF domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG17559 11-Aug-17 DroID_v2017_08 "Drer\ryk, Drer\met, Drer\mst1ra, Drer\mst1rb" "Scer\SCH9, Scer\KIN1, Scer\RCK1" "Cele\kin-9, Cele\C24G6.2, Cele\lin-18, Cele\scd-2, Cele\F11E6.8" Xtro\ryk "Mmus\Ryk, Mmus\Mst1r, Mmus\Met" "Hsap\MET, Hsap\MST1R, Hsap\RYK, Hsap\WIF1" " embryonic stage--larval stage , embryonic stage | blastoderm , embryonic stage | gastrula , embryonic stage | late , embryonic stage | stage >= 5 , embryonic stage | stage 11 , embryonic stage | extended germ band , embryonic stage | stage 6-12 " "

20-80% egg length , cephalic furrow

, imaginal precursor

, amnioproctodeal invagination

, organism | striped

, embryonic/larval tracheal pit | surrounding

,organism | stripes

, ventral furrow

" "viable,visible,partially lethal - majority die,some die during pupal stage" "presumptive embryonic salivary gland,embryonic/larval salivary gland,lateral transverse muscle,chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0003068 per period http://flybase.org/reports/FBgn0003068 "FBgn0000321, FBgn0020918" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O77059 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with per protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Clk protein heterodimerization activity ; GO:0046982 | non-traceable author statement transcription cofactor activity ; GO:0003712 | non-traceable author statement transcription factor binding ; GO:0008134 | inferred from physical interaction with Clk protein binding ; GO:0005515 | inferred from physical interaction with dco inferred from physical interaction with tim inferred from physical interaction with Clk protein heterodimerization activity ; GO:0046982 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with dco transcription corepressor activity ; GO:0003714 | traceable author statement "circadian rhythm ; GO:0007623 | traceable author statement regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | traceable author statement eclosion rhythm ; GO:0008062 | inferred from mutant phenotype negative regulation of transcription regulatory region DNA binding ; GO:2000678 | inferred from direct assay regulation of protein phosphorylation ; GO:0001932 | inferred from mutant phenotype entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | non-traceable author statement circadian temperature homeostasis ; GO:0060086 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay circadian behavior ; GO:0048512 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype eclosion rhythm ; GO:0008062 | traceable author statement copulation ; GO:0007620 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement response to temperature stimulus ; GO:0009266 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | non-traceable author statement regulation of locomotor rhythm ; GO:1904059 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | traceable author statement entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay eclosion rhythm ; GO:0008062 | non-traceable author statement rhythmic behavior ; GO:0007622 | traceable author statement age-dependent response to oxidative stress ; GO:0001306 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement response to light stimulus ; GO:0009416 | traceable author statement circadian sleep/wake cycle ; GO:0042745 | traceable author statement mating behavior ; GO:0007617 | inferred from mutant phenotype behavioral response to cocaine ; GO:0048148 | non-traceable author statement" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement cytoplasm ; GO:0005737 | non-traceable author statement nucleus ; GO:0005634 | non-traceable author statement nucleus ; GO:0005634 | traceable author statement "PER, per, dper, EG:155E2.4, CG2647, dPER, Per, Clk, clk-6, period, mel_per, dmper, Per-2" "IPR000014:PAS domain, IPR013767:PAS fold" CG2647 11-Aug-17 DroID_v2017_08 "Drer\per2, Drer\per1a, Drer\per3, Drer\per1b" - Cele\lin-42 "Xtro\per1, Xtro\per2, Xtro\per3" "Mmus\Per3, Mmus\Per2, Mmus\Per1" "Hsap\PER2, Hsap\PER3, Hsap\PER1" adult stage " adult lateral neuron

, adult head

, photoreceptor cell

, adult brain | restricted

" adult stage " lamina neuropil

, supraesophageal ganglion

, neuropil

, optic lobe

, optic chiasma

, photoreceptor cell

, ocellus

" "locomotor rhythm defective,eclosion rhythm defective,song defective,recessive,circadian rhythm defective,neuroanatomy defective,semi-sterile,conditional,semi-fertile,sleep defective,behavior defective,visual behavior defective,wild-type,circadian behavior defective,male,mating rhythm defective,male limited,heat sensitive,memory defective,courtship behavior defective,semidominant,cold sensitive,mating defective,viable,photoperiod response variant,stress response defective,gravitaxis defective,aging defective,visible,body color defective" "Malpighian tubule,indirect flight muscle motor neuron MN5,posterior adult hindgut,pericardial cell,trichogen cell,mesothoracic tergum" FBgn0260632 dl dorsal http://flybase.org/reports/FBgn0260632 protein_coding_gene "repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with gro sequence-specific DNA binding ; GO:0043565 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with Dsp1 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 high mobility group box 1 binding ; GO:0070379 | inferred from physical interaction with Dsp1 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from genetic interaction with twi protein binding ; GO:0005515 | inferred from physical interaction with tamo protein binding ; GO:0005515 | inferred from physical interaction with lwr inferred from physical interaction with Dlip3 inferred from physical interaction with smt3" "ectoderm development ; GO:0007398 | non-traceable author statement defense response ; GO:0006952 | traceable author statement gastrulation involving germ band extension ; GO:0010004 | traceable author statement mesodermal cell fate specification ; GO:0007501 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement immune response ; GO:0006955 | inferred from expression pattern plasmatocyte differentiation ; GO:0042387 | inferred from mutant phenotype gastrulation ; GO:0007369 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype NIK/NF-kappaB signaling ; GO:0038061 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 heart development ; GO:0007507 | non-traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype I-kappaB kinase/NF-kappaB signaling ; GO:0007249 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 dorsal/ventral axis specification ; GO:0009950 | traceable author statement regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mesoderm development ; GO:0007498 | non-traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement immune response ; GO:0006955 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | non-traceable author statement ventral cord development ; GO:0007419 | non-traceable author statement dorsal/ventral pattern formation ; GO:0009953 | non-traceable author statement germ cell migration ; GO:0008354 | traceable author statement peripheral nervous system neuron development ; GO:0048935 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement ectodermal cell fate specification ; GO:0001715 | traceable author statement regulation of hemocyte proliferation ; GO:0035206 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay response to cytokine ; GO:0034097 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 melanization defense response ; GO:0035006 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement anterior/posterior pattern specification ; GO:0009952 | traceable author statement negative regulation of gene expression ; GO:0010629 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 cytoplasm ; GO:0005737 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay I-kappaB/NF-kappaB complex ; GO:0033256 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 subsynaptic reticulum ; GO:0071212 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleus ; GO:0005634 | non-traceable author statement "dl, Dl, CG6667, dL, fs(2)k10816, anon-EST:GressD7, mat(2)dorsal, DL, GSd447, d;, Dorsal, Dor, NFkappaB, dorsal" "IPR000451:NF-kappa-B/Dorsal, IPR002909:IPT domain, IPR008967:p53-like transcription factor, DNA-binding, IPR011539:Rel homology domain (RHD), DNA-binding domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR030492:Rel homology domain, conserved site, IPR033926:NFkappaB IPT domain, IPR011363:Dorsal-related immunity factor Dif, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032397:Rel homology dimerisation domain" CG6667 11-Aug-17 DroID_v2017_08 "Drer\relb, Drer\rel, Drer\nfkb2, Drer\rela, Drer\nfkb1" - - "Xtro\relb, Xtro\rela, Xtro\rel" "Mmus\Nfkb2, Mmus\Nfkb1, Mmus\Rela, Mmus\Rel, Mmus\Relb" "Hsap\NFKB1, Hsap\RELA, Hsap\NFKB2, Hsap\REL, Hsap\RELB" " embryonic stage | 0-2.5 hr , larval stage , embryonic stage | >=6hr , adult stage | male , adult stage && oogenesis stage , embryonic stage | , ovary

,

ubiquitous " " embryonic stage | stage 2-3 , embryonic stage | stage 3-9 , embryonic stage | stage 3-7 , embryonic stage | stage 2 , embryonic stage | stage 1-17 , adult stage && oogenesis stage | stage S9-12 , embryonic stage | stage 7-14 , embryonic stage | stage 2-4 , adult stage , embryonic stage | stage 3-5 , embryonic stage | stage 7 , egg stage | unfertilized egg " " organism | ubiquitous

, organism | dorsal ventral gradient

,

ubiquitous , nurse cell

, ventral furrow

, ovary

, mesoderm

, unfertilized egg

" FBgn0036107 galla-2 galla-2 http://flybase.org/reports/FBgn0036107 protein_coding_gene molecular_function ; GO:0003674 | no biological data available iron-sulfur cluster assembly ; GO:0016226 | inferred from biological aspect of ancestor with PANTHER:PTN000272123 CIA complex ; GO:0097361 | inferred from biological aspect of ancestor with PANTHER:PTN000962349 "CG7949, galla-2" IPR002744:Domain of unknown function DUF59 CG7949 11-Aug-17 DroID_v2017_08 Drer\fam96b Scer\CIA2 Cele\F45G2.10 Xtro\fam96b "Mmus\Fam96a, Mmus\Fam96b" "Hsap\FAM96A, Hsap\FAM96B" viable FBgn0010607 l(2)05714 lethal (2) 05714 http://flybase.org/reports/FBgn0010607 FBgn0031658 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "l(2)05715, CG8886, l(2)05714" - CG8886 11-Aug-17 DroID_v2017_08 - - - - - - "lethal,recessive,viable,visible" mesothoracic tergum FBgn0003345 sd scalloped http://flybase.org/reports/FBgn0003345 "FBgn0025967, FBgn0026840, FBgn0027221, FBgn0027225, FBgn0027247, FBgn0027258, FBgn0040146, FBgn0062702" protein_coding_gene "protein domain specific binding ; GO:0019904 | inferred from physical interaction with UniProtKB:Q26366 RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with yki transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q45VV3 RNA polymerase II transcription factor binding ; GO:0001085 | inferred from biological aspect of ancestor with PANTHER:PTN000216669" imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype cardiac muscle cell development ; GO:0055013 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from genetic interaction with vg imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from direct assay somatic muscle development ; GO:0007525 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement epithelium development ; GO:0060429 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype inferred from genetic interaction with vg stem cell proliferation ; GO:0072089 | inferred from direct assay embryonic organ development ; GO:0048568 | inferred from biological aspect of ancestor with PANTHER:PTN000931329 negative regulation of hippo signaling ; GO:0035331 | inferred from genetic interaction with yki sensory organ development ; GO:0007423 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype regulation of heart morphogenesis ; GO:2000826 | inferred from genetic interaction with yki compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN000216669 "sd, CG8544, Sd, EP(X)1088, DROEXO, DROEXO2, sp, l(1)G0239, l(1)G0262, l(1)G0309, l(1)G0483, clone 2.14, anon-EST:Liang-2.14, l(1)G0315, l(1)III, l(1)HF394, EP1088, SD, TEAD" IPR000818:TEA/ATTS domain CG8544 11-Aug-17 DroID_v2017_08 "Drer\tead1a, Drer\tead3a, Drer\tead3b, Drer\tead1b" Scer\TEC1 Cele\egl-44 "Xtro\tead4, Xtro\tead1" "Mmus\Tead4, Mmus\Tead2, Mmus\Tead1, Mmus\Tead3" "Hsap\TEAD3, Hsap\TEAD1, Hsap\TEAD4, Hsap\TEAD2" " larval stage , adult stage , embryonic stage , embryonic stage | >= stage 9 , embryonic stage | >= stage 11 " " anepisternum | precursor

, photoreceptor cell

, perineurial sheath cell

, larval labral segment sense organ

, maxillary palp sense organ

, calyx of mushroom body

, subesophageal ganglion | restricted

, central nervous system

, scutellum | precursor

, microchaeta

, subesophageal ganglion

, sense organ

, sacculus

, peripheral nervous system

, mesothoracic extracoxal depressor muscle 66

, eye-antennal disc

, protocerebrum

, supraesophageal ganglion

, dorsal mesothoracic disc

, antennal sense organ

" "visible,viable,lethal,recessive,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,stress response defective,dominant,fertile,chemosensitive behavior defective,taste perception defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,wild-type,mitotic cell cycle defective,somatic clone,developmental rate defective,neuroanatomy defective,male fertile,female fertile,male sterile,increased cell death,partially lethal - majority die,size defective,decreased cell number,lethal - all die during pupal stage" "eye,wing disc,wing,wing pouch,somatic clone,midgut constriction,A1-7 lateral longitudinal muscle 1,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,embryonic/larval cardial cell,heat sensitive,macrochaeta,posterior wing margin,chaeta,scutellum,adult thorax,ectopic,microchaeta,wing vein,anterior,wing margin,capitellum,wing sensillum,scutellar bristle,haltere,macrochaeta & wing,wing blade,wing vein & macrochaeta,head,crossvein,wing hinge,posterior scutellar bristle,wing & macrochaeta,interommatidial bristle,leg,unguis,indirect flight muscle,metathoracic laterotergite,segmental nerve,wing vein L5,ommatidium,ventral thoracic disc,adult,pupa,A1-7 dorsal acute muscle 1,somatic muscle,wing vein L2,wing vein L4,adult head,lobula plate,lamina,mesothoracic tergum,eye disc | third instar larval stage,epithelium,egg chamber" DRSC20370 K 0.051011668 0.12632254 -0.754168718 1.473546613 1.980753536 0.793557353 FBgn0002522 lab labial http://flybase.org/reports/FBgn0002522 FBgn0010742 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with exd transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from physical interaction with exd enhancer binding ; GO:0035326 | inferred from physical interaction with dpp" cell differentiation ; GO:0030154 | traceable author statement brain segmentation ; GO:0035284 | inferred from genetic interaction with vvl head morphogenesis ; GO:0060323 | inferred from mutant phenotype midgut development ; GO:0007494 | traceable author statement brain development ; GO:0007420 | inferred from genetic interaction with vvl cell fate determination ; GO:0001709 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype positive regulation of decapentaplegic signaling pathway ; GO:0090098 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "DmLab, Lab, F121, lb, F24, F90-2, EfR9, l(3)84Ac, l(3)01241, F90, CG1264, BG:DS00004.9, lab, LAB, Dm lab, Dmlab" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG1264 11-Aug-17 DroID_v2017_08 "Drer\hoxb3a, Drer\hoxc4a, Drer\hoxa9b, Drer\hoxd3a, Drer\hoxa2b, Drer\hoxa1a, Drer\hoxc6b, Drer\meox1, Drer\hoxb6a, Drer\hoxb2a, Drer\hoxb1b, Drer\meox2b, Drer\hoxb5b, Drer\hoxc5a, Drer\gbx1, Drer\hoxb6b, Drer\gbx2, Drer\gsx2, Drer\pdx1, Drer\hoxa4a, Drer\mnx1, Drer\hoxd4a, Drer\hoxc6a, Drer\hoxb7a, Drer\hoxb4a, Drer\hoxa3a, Drer\hoxa5a, Drer\hoxc1a, Drer\hoxc3a, Drer\gsx1, Drer\hoxc8a, Drer\mnx2a, Drer\meox2a, Drer\hoxb8b, Drer\hoxb5a, Drer\hoxb1a" "Scer\YOX1, Scer\YHP1, Scer\PHO2" "Cele\ceh-16, Cele\ceh-13" "Xtro\hoxc8, Xtro\hoxc3, Xtro\hoxb3, Xtro\gsx2, Xtro\gbx2.2, Xtro\hoxb5, Xtro\hoxb7, Xtro\hoxb2, Xtro\hoxa2, Xtro\hoxd1, Xtro\gbx2.1, Xtro\hoxa5, Xtro\meox2, Xtro\mnx1, Xtro\hoxb1, Xtro\gsx1, Xtro\hoxa1, Xtro\hoxc5, Xtro\hoxb6, Xtro\hoxb4, Xtro\hoxb8, Xtro\hoxc4, Xtro\hoxd8, Xtro\pdx1, Xtro\hoxa3, Xtro\hoxd3" "Mmus\Hoxa1, Mmus\Gsx2, Mmus\Hoxb8, Mmus\Hoxc8, Mmus\Hoxb4, Mmus\Gbx2, Mmus\Hoxb5, Mmus\Hoxa5, Mmus\Gsx1, Mmus\Hoxd4, Mmus\Meox2, Mmus\Hoxb1, Mmus\Meox1, Mmus\Hoxb6, Mmus\Mnx1, Mmus\Hoxb2, Mmus\Hoxd1, Mmus\Hoxc5, Mmus\Hoxb7, Mmus\Hoxa4, Mmus\Hoxa7, Mmus\Hoxc4, Mmus\Hoxa6, Mmus\Gbx1, Mmus\Hoxa2, Mmus\Hoxa3, Mmus\Hoxd3, Mmus\Pdx1, Mmus\Hoxd8, Mmus\Hoxb3, Mmus\Hoxc6" "Hsap\HOXA3, Hsap\GBX1, Hsap\HOXA1, Hsap\GSX2, Hsap\HOXB4, Hsap\MEOX2, Hsap\PDX1, Hsap\HOXB1, Hsap\HOXA6, Hsap\HOXD1, Hsap\HOXA7, Hsap\HOXC8, Hsap\GSX1, Hsap\MEOX1, Hsap\HOXA5, Hsap\HOXA4, Hsap\HOXA2, Hsap\HOXC4, Hsap\HOXB7, Hsap\MNX1, Hsap\HOXD3, Hsap\HOXD4, Hsap\HOXC5, Hsap\HOXD8, Hsap\HOXC6, Hsap\HOXB8, Hsap\HOXB5, Hsap\HOXB3, Hsap\HOXB2, Hsap\HOXB6, Hsap\GBX2" " embryonic stage | stage 9-11 , embryonic stage | >=2-4 hr , embryonic stage , embryonic stage | 0-24 hr , embryonic stage | 2-24 hr , embryonic stage | extended germ band , embryonic stage | contracted germ band , larval stage && pupal stage , embryonic stage && larval stage && pupal stage , embryonic stage | 12-14 hr " " cephalic furrow | anterior to

, mesothoracic segment | dorsal

{ + Antp*, BX-C- } , parasegment 4,5

{ + Antp* } , mesothoracic segment | dorsal

{ + Scr*, Antp*, BX-C- } , prothoracic segment | posterior <&> dorsal

{ 0 BX-C- } , metathoracic segment | dorsal

{ + Scr*, Antp*, BX-C- } , posterior midgut proper primordium

, metathoracic segment | dorsal

{ + Antp*, BX-C- } , parasegment 4..13 midline

{ + tsh-, Antp* } , prothoracic segment | dorsal

{ + Scr*, Antp*, BX-C- } , abdominal segment 1--8

, prothoracic segment | dorsal

{ + Antp*, BX-C- } , hypopharyngeal lobe | anlagen

, central nervous system

, embryonic mandibular segment

, parasegment 4..13 tracheal placode

{ + tsh- } ,

{ + Antp*, BX-C- } , embryonic procephalic segment | anlagen

, embryonic/larval midgut

, abdominal segment 1..8 | dorsal

{ + Scr*, Antp*, BX-C- } " " embryonic stage | stage 9-11 , embryonic stage | stage 12 , embryonic stage | mid-late , embryonic stage | stage 13-17 , embryonic stage , embryonic stage , embryonic stage | stage 13-14 " " ectoderm && intercalary segment

, embryonic/larval midgut | restricted

, deuterocerebral neuroblast | subset

, endoderm

{ + abd-AM1 } , parasegment 7 endoderm

{ + Ubxhs.PU } , embryonic central nervous system | restricted

, endoderm &&of parasegment 7--12

, midgut

, anterior midgut proper primordium

, midgut

{ - dpps4 } , endoderm | anterior

, parasegment 1..7 midgut

{ + Ubx* } , larval sense organ | precursor

, dorsal ridge

, posterior midgut proper primordium

, embryonic/larval midgut

{ - Ubx* } , parasegment 8..12 midgut

{ v wgx* } , procephalic segment | restricted

, midgut

{ + Pc* } , tritocerebral neuroblast

" "viable,fertile,lethal,recessive,wild-type,visible,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "crystal cell,embryonic head,embryonic/larval salivary gland,arista,cuprophilic cell,midgut interstitial cell,cephalopharyngeal skeleton,tritocerebral neuromere,tritocerebral commissure,longitudinal connective,postorbital bristle,supernumerary,adult midgut,embryonic/larval midgut,embryonic brain,temperature conditional,mouth hooks,tritocerebrum,embryonic tritocerebrum,embryonic/larval tritocerebrum,embryonic/larval tritocerebral commissure,frontal connective,wing vein,wing margin" DRSC12627 K -0.529910814 -0.564672322 -0.411196595 0.097667134 1.571932762 1.455156612 FBgn0260799 p120ctn Adherens junction protein p120 http://flybase.org/reports/FBgn0260799 protein_coding_gene cadherin binding ; GO:0045296 | inferred from electronic annotation with InterPro:IPR028446 single organismal cell-cell adhesion ; GO:0016337 | inferred from electronic annotation with InterPro:IPR028435 regulation of actin cytoskeleton organization ; GO:0032956 | inferred from electronic annotation with InterPro:IPR028446 embryonic body morphogenesis ; GO:0010172 | inferred from electronic annotation with InterPro:IPR028446 dendritic spine morphogenesis ; GO:0060997 | inferred from mutant phenotype adherens junction maintenance ; GO:0034334 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from genetic interaction with arm inferred from genetic interaction with shg compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype inferred from genetic interaction with shg inferred from genetic interaction with Rho1 cell-cell adherens junction ; GO:0005913 | inferred from electronic annotation with InterPro:IPR028446 cytoplasm ; GO:0005737 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay inferred from physical interaction with arm inferred from physical interaction with shg centrosome ; GO:0005813 | inferred from direct assay "dP120ctn, p120, p120[ctn], Dp120ctn, Dp120[ctn], CG17484, p120ctn, P120, P120-catenin, P120ctn, dp120ctn" "IPR000225:Armadillo, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR028435:Plakophilin/Delta catenin, IPR028446:Juxtamembrane domain-associated catenin" CG17484 11-Aug-17 DroID_v2017_08 "Drer\arvcfa, Drer\pkp3b, Drer\arvcfb, Drer\pkp1, Drer\ctnnd1, Drer\pkp2, Drer\jupb, Drer\armc3, Drer\armc4, Drer\pkp1b, Drer\pkp4, Drer\pkp3a, Drer\ctnnd2b, Drer\ctnnd2a" Scer\VAC8 "Cele\hmp-2, Cele\jac-1" "Xtro\pkp3, Xtro\armc4, Xtro\pkp4, Xtro\ctnnb1, Xtro\ctnnd2, Xtro\armc3, Xtro\pkp1, Xtro\ctnnd1, Xtro\arvcf" "Mmus\Ctnnb1, Mmus\Armc3, Mmus\Pkp4, Mmus\Ctnnd2, Mmus\Pkp1, Mmus\Pkp3, Mmus\Ctnnd1, Mmus\Arvcf, Mmus\Jup, Mmus\Pkp2, Mmus\Armc4" "Hsap\CTNND2, Hsap\PKP4, Hsap\CTNND1, Hsap\PKP3, Hsap\PKP2, Hsap\JUP, Hsap\CTNNB1, Hsap\ARMC3, Hsap\ARVCF, Hsap\PKP1" embryonic stage " embryonic foregut

,

ubiquitous , anterior embryonic/larval midgut

, midgut constriction

, embryonic hindgut

, posterior embryonic/larval midgut

, embryonic central nervous system

" " larval stage , embryonic stage , oogenesis stage , embryonic stage | stage >9 , embryonic stage && larval stage , embryonic stage | stage 4-9 " " eye disc

, morphogenetic furrow | anterior to

, embryonic sensory system

, neuroblast

, morphogenetic furrow

, larval brain | restricted

, ganglion mother cell

, germline cell

, follicle cell

, embryonic epidermis

, embryonic tracheal system

, embryonic central nervous system | restricted

, neuron

, embryonic peripheral nervous system | restricted

, border follicle cell

, embryonic midgut

" FBgn0259211 grh grainy head http://flybase.org/reports/FBgn0259211 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with grh" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from expression pattern rhabdomere development ; GO:0042052 | inferred from mutant phenotype epithelial cell morphogenesis ; GO:0003382 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from expression pattern ventral cord development ; GO:0007419 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype ganglion mother cell fate determination ; GO:0007402 | traceable author statement tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype regulation of tube architecture, open tracheal system ; GO:0035152 | traceable author statement chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | traceable author statement membrane organization ; GO:0061024 | traceable author statement R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype ventral cord development ; GO:0007419 | non-traceable author statement chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype regulation of wound healing ; GO:0061041 | inferred from mutant phenotype plasma membrane organization ; GO:0007009 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Grh, grh, CG42311, Elf1, Elf-1, Gh, CG5058, NTF1, EG:191D12.1, l(2)06850, elf1(CAG)[[7]], NTF-1, DREB, NTF-1/Elf-1, elf1, Ntf, Elf-1/NTF-1, l(2)s2140, l(2)IM45, hsk, Ntf1, NTF, ntf-1, GRH, BcDNA:LD38807, CG30111, ELF1" "IPR007604:CP2 transcription factor, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011990:Tetratricopeptide-like helical domain" CG42311 11-Aug-17 DroID_v2017_08 "Drer\ubp1, Drer\grhl3, Drer\grhl2b, Drer\tfcp2, Drer\grhl1, Drer\grhl2a" - Cele\grh-1 "Xtro\ubp1, Xtro\grhl1, Xtro\tfcp2, Xtro\grhl3, Xtro\grhl2" "Mmus\Grhl2, Mmus\Tfcp2, Mmus\Grhl3, Mmus\Tfcp2l1, Mmus\Grhl1, Mmus\Ubp1" "Hsap\GRHL2, Hsap\GRHL3, Hsap\GRHL1, Hsap\TFCP2L1, Hsap\UBP1, Hsap\TFCP2" embryonic stage " ventral nerve cord

, epidermis

, embryonic brain

" " larval stage , embryonic stage , larval stage | third instar , embryonic stage | stage >=11 " " embryonic/larval hindgut

, embryonic/larval foregut

, imaginal disc

, embryonic/larval anterior spiracle

, dorsal mesothoracic disc

, embryonic/larval trachea

, embryonic/larval proventriculus

, ventral nerve cord | segmentally repeated

, neuroblast

, epidermis

, larval optic lobe

" DRSC05683 I -1.006478044 -4.205843924 -0.990553514 -1.199217732 0.398120497 0.743839703 FBgn0262733 Src64B Src oncogene at 64B http://flybase.org/reports/FBgn0262733 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity receptor binding ; GO:0005102 | inferred from physical interaction with drl" "dorsal closure ; GO:0007391 | traceable author statement female germline ring canal formation, actin assembly ; GO:0008302 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of protein kinase activity ; GO:0045860 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of synaptic plasticity ; GO:0048167 | inferred from genetic interaction with GluRIIA parallel actin filament bundle assembly ; GO:0030046 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 filtration diaphragm assembly ; GO:0036058 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from genetic interaction with Src42A transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 JNK cascade ; GO:0007254 | traceable author statement ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype female germline ring canal stabilization ; GO:0008335 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype adherens junction organization ; GO:0034332 | inferred from mutant phenotype cell migration ; GO:0016477 | inferred from biological aspect of ancestor with PANTHER:PTN001231165 germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 learning or memory ; GO:0007611 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from genetic interaction with Fak regulation of actin polymerization or depolymerization ; GO:0008064 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype epithelial cell-cell adhesion ; GO:0090136 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 cytosol ; GO:0005829 | inferred from direct assay germline ring canal ; GO:0045172 | inferred from direct assay "Src64, src, Src64B, D-Src64B, Src, src64, src64B, CG7524, src64b, dSrc, DSrc64B, Dsrc64B, SRC 64B, DSrc64, DmHD-358, dsrc, Dsrc64, Dm SRC1, DSRC64, DSrc, Src1, Dsrc, D-src, c-src, src1, HD-358, C-src1, MRE5, Src64b, SRC64B" "IPR000719:Protein kinase domain, IPR000980:SH2 domain, IPR001452:SH3 domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG7524 11-Aug-17 DroID_v2017_08 "Drer\btk, Drer\abl1, Drer\yrk, Drer\sla, Drer\tyk2, Drer\frk, Drer\tec, Drer\sla2, Drer\ptk6b, Drer\fynb, Drer\abl2, Drer\lyn, Drer\ptk6a, Drer\itk, Drer\csk, Drer\si:ch73-340m8.2, Drer\zgc:194282, Drer\matk, Drer\fyna, Drer\blk, Drer\src, Drer\txk, Drer\hck, Drer\yes1, Drer\jak1, Drer\sla1, Drer\jak3, Drer\jak2a, Drer\lck, Drer\jak2b" - "Cele\Y38H6C.20, Cele\src-1, Cele\src-2, Cele\abl-1, Cele\Y47G6A.5" "Xtro\csk, Xtro\src, Xtro\lck, Xtro\abl1, Xtro\jak1, Xtro\btk, Xtro\jak2, Xtro\fyn, Xtro\jak3, Xtro\tec, Xtro\yes1, Xtro\sla2, Xtro\fgr, Xtro\sla, Xtro\abl2, Xtro\tyk2, Xtro\lyn" "Mmus\Blk, Mmus\Txk, Mmus\Fyn, Mmus\Jak1, Mmus\Bmx, Mmus\Ptk6, Mmus\Matk, Mmus\Tyk2, Mmus\Jak3, Mmus\Abl1, Mmus\Hck, Mmus\Fgr, Mmus\Csk, Mmus\Frk, Mmus\Sla2, Mmus\Srms, Mmus\Lyn, Mmus\Sla, Mmus\Lck, Mmus\Yes1, Mmus\Tec, Mmus\Btk, Mmus\Itk, Mmus\Abl2, Mmus\Src, Mmus\Jak2" "Hsap\SLA2, Hsap\TXK, Hsap\SLA, Hsap\BLK, Hsap\ABL2, Hsap\LCK, Hsap\TYK2, Hsap\LYN, Hsap\ITK, Hsap\JAK1, Hsap\FRK, Hsap\CSK, Hsap\SRC, Hsap\TEC, Hsap\SRMS, Hsap\FGR, Hsap\JAK3, Hsap\FYN, Hsap\MATK, Hsap\PTK6, Hsap\JAK2, Hsap\BTK, Hsap\HCK, Hsap\YES1, Hsap\BMX, Hsap\ABL1" " adult stage && oogenesis stage , adult stage | female , prepupal stage--pupal stage , oogenesis stage && adult stage | female , embryonic stage " " oocyte

, ovary

" adult stage && oogenesis stage " nurse cell | restricted

, ring canal

" FBgn0005648 Pabp2 Pabp2 http://flybase.org/reports/FBgn0005648 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VSK8 poly(A) binding ; GO:0008143 | inferred from sequence or structural similarity with SGD:S000005075 RNA binding ; GO:0003723 | inferred from direct assay poly(A) binding ; GO:0008143 | inferred from direct assay "mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from direct assay mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of protein glycosylation ; GO:0060050 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "pabp2, CG2163, pAbp2, rox2, dpabII, ROX2, Rox2, Pabp2, PABP2, PABPN1" IPR000504:RNA recognition motif domain CG2163 11-Aug-17 DroID_v2017_08 "Drer\pabpn1, Drer\rnps1, Drer\pabpn1l" "Scer\NSR1, Scer\SGN1" "Cele\T08B6.5, Cele\pabp-2, Cele\EEED8.4, Cele\EEED8.12" "Xtro\pabpn1, Xtro\pabpn1l, Xtro\bcl2l2, Xtro\rnps1" "Mmus\Bcl2l2, Mmus\Rnps1, Mmus\Dnd1, Mmus\Pabpn1, Mmus\Pabpn1l" "Hsap\BCL2L2, Hsap\DND1, Hsap\RNPS1, Hsap\PABPN1, Hsap\BCL2L2-PABPN1, Hsap\PABPN1L" " larval stage , embryonic stage | late , embryonic stage -- adult stage , adult stage , pupal stage , larval stage && pupal stage && adult stage " ovary

" larval stage , adult stage | female && oogenesis stage , embryonic stage " " follicle cell

, female germline stem cell

" "partially lethal - majority die,recessive,lethal,female semi-sterile,maternal effect,mitotic cell cycle defective,germline clone,viable,neuroanatomy defective,some die during pupal stage" "chorion,egg chamber,embryo,maternal effect,female germline cell,chorion | germline clone,germline clone,embryonic/larval neuroblast,ganglion mother cell" DRSC07501 IEK 0.090881594 -1.868369048 -0.096971143 -1.736825069 1.681849471 2.510676261 FBgn0011758 B-H1 BarH1 http://flybase.org/reports/FBgn0011758 - protein_coding_gene "transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001228 | inferred from biological aspect of ancestor with PANTHER:PTN001551673 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001551673 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from mutant phenotype" "compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype inferred from genetic interaction with Lim1 eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "BarH, BarH1, BH1, Bar, Bar H1, CG5529, BarHI, barH1, barh1, Bar-H1, B-H1, bar-h1, Barh1" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR020479:Homeobox domain, metazoa" CG5529 11-Aug-17 DroID_v2017_08 "Drer\lbx2, Drer\nkx1.2lb, Drer\LOC100008066, Drer\barhl2, Drer\vox, Drer\lbx1a, Drer\barhl1a, Drer\tlx2, Drer\barhl1b, Drer\ved, Drer\pnx, Drer\tlx1, Drer\barx2, Drer\tlx3b, Drer\dbx1b, Drer\hlx1, Drer\barx1, Drer\lbx1b" - "Cele\unc-4, Cele\ceh-30, Cele\ceh-31" "Xtro\tlx1, Xtro\tlx2, Xtro\barhl1, Xtro\dbx1, Xtro\nkx1-1, Xtro\nkx3-1, Xtro\barhl2, Xtro\ventx1.2, Xtro\hlx, Xtro\nkx1-2, Xtro\barx1, Xtro\tlx3" "Mmus\Tlx1, Mmus\Lbx1, Mmus\Tlx3, Mmus\Gbx2, Mmus\Hlx, Mmus\Barx1, Mmus\Dbx1, Mmus\Tlx2, Mmus\Lbx2, Mmus\Barx2, Mmus\Nkx1-1, Mmus\Barhl1, Mmus\Barhl2, Mmus\Nkx1-2, Mmus\Dbx2" "Hsap\HLX, Hsap\BARHL2, Hsap\NKX1-1, Hsap\TLX3, Hsap\BARX2, Hsap\LBX2, Hsap\DBX1, Hsap\TLX1, Hsap\TLX2, Hsap\BARX1, Hsap\LBX1, Hsap\BARHL1, Hsap\DBX2" " pupal stage , embryonic stage , embryonic stage -- adult stage " " peripheral nervous system

, thecogen cell

, external sensory organ

, embryonic central nervous system

, neuron

" " larval stage | late -- P | early , embryonic stage " " photoreceptor cell R6 | presumptive

, neuron

, peripheral nervous system

, embryonic central nervous system

, external sensory organ

, thecogen cell

" "lethal,recessive,visible,viable" "tarsal segment 3,tarsal segment 4,pretarsus,ommatidium,sensillum trichodeum,eye photoreceptor cell,eye,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,cone cell,primary pigment cell,posterior cone cell,anterior cone cell,morphogenetic furrow,photoreceptor cell,ventral thoracic disc,tarsal segment 4 & leg sensillumap-md544" FBgn0003285 rst roughest http://flybase.org/reports/FBgn0003285 "FBgn0001272, FBgn0005381" protein_coding_gene PDZ domain binding ; GO:0030165 | inferred from physical interaction with X11L lateral inhibition ; GO:0046331 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | traceable author statement compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from genetic interaction with hbs regulation of striated muscle tissue development ; GO:0016202 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | traceable author statement retinal cell programmed cell death ; GO:0046666 | traceable author statement cell-cell adherens junction ; GO:0005913 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity apical part of cell ; GO:0045177 | inferred from direct assay integral component of membrane ; GO:0016021 | traceable author statement "IrreC, irreC, IrrecC, IrreC-rst, irreC-rst, IRREC/RST, rst/irrecC, IrreC-Rst, rst-irreC, CT13684, IREE-C, rst-irrecC, irrecC-rst, UB883, CG4125, rst, IrreC/Rst, Rst, Irre-C, Rst/IrreC" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG4125 11-Aug-17 DroID_v2017_08 "Drer\kirrel3b, Drer\si:ch1073-459j12.1, Drer\lrit3b, Drer\ush2a, Drer\kirrel3l, Drer\lrit1b, Drer\kirrela, Drer\kirrelb, Drer\sdk1a, Drer\dscama, Drer\tmigd1, Drer\itgb4, Drer\ncam1b, Drer\sdk1b, Drer\lrit1a, Drer\igsf9a, Drer\lrit3a, Drer\kirrel3a, Drer\igsf9bb, Drer\paplna" - Cele\syg-1 "Xtro\kirrel2, Xtro\lrit3, Xtro\papln, Xtro\kirrel, Xtro\igsf9b" "Mmus\Kirrel3, Mmus\Ptprq, Mmus\Igsf9b, Mmus\Papln, Mmus\Sdk1, Mmus\Kirrel, Mmus\Lrit3, Mmus\Lrit1, Mmus\Kirrel2" "Hsap\KIRREL, Hsap\PAPLN, Hsap\KIRREL3, Hsap\LRIT3, Hsap\SDK1, Hsap\USH2A, Hsap\KIRREL2, Hsap\IGSF9B, Hsap\LRIT1" " embryonic stage | stage 11 , pupal stage , larval stage | third instar " " embryonic labial segment

, embryonic maxillary segment

, secondary pigment cell

, mesoderm | restricted

, lamina

, larval outer optic anlage

, imaginal disc

, embryonic mandibular segment

, eye-antennal disc

, labral segment

, ventral midline

, retina

, medulla | restricted

, tertiary pigment cell

" "visual behavior defective,heat sensitive,visible,recessive,neuroanatomy defective,female sterile,partially lethal - majority die,decreased cell death,female fertile,poor,viable,reduced,small body,male sterile,eye color defective,dominant,cell death defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type" "ommatidium,interommatidial bristle,cone cell,presumptive embryonic/larval muscle system,optic chiasma,ectopic,antennal segment 3 sensillum,sensillum basiconicum of antennal segment 3,antennal disc,eye disc,embryonic somatic muscle,ommatidial precursor cluster,eye,inter-ommatidial cell,supernumerary,primary pigment cell,inter-ommatidial precursor cell,cell-cell junction,adherens junction,anterior vertical bristle,posterior vertical bristle,postvertical bristle,embryonic myoblast,embryonic/larval salivary gland,thorax & microchaeta,photoreceptor cell pigment granule,secondary pigment cell,tertiary pigment cell,optic lobe,embryonic/larval muscle system,embryonic/larval optic lobe,lamina neuropil,sensillum trichodeum of antennal segment 3,sacculus,four cone-cell ommatidial precursor cluster,lamina,lobula,lobula plate,inter-ommatidial precursor cell | P-stage,embryonic/larval garland cell | third instar larval stage,nucleus | supernumerary | third instar larval stagepros.PMG,chaeta,wing margin,wing hair" FBgn0013469 klu klumpfuss http://flybase.org/reports/FBgn0013469 "FBgn0010931, FBgn0010938" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 positive regulation of neuroblast proliferation ; GO:0002052 | inferred from mutant phenotype negative regulation of Ras protein signal transduction ; GO:0046580 | non-traceable author statement tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype neuronal stem cell population maintenance ; GO:0097150 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | inferred from mutant phenotype positive regulation of compound eye retinal cell programmed cell death ; GO:0046672 | inferred from mutant phenotype regulation of stem cell division ; GO:2000035 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "P09036, l(3)10052, l(3)09036, CG12296, klu, Klu, KLU" IPR013087:Zinc finger C2H2-type CG12296 11-Aug-17 DroID_v2017_08 "Drer\si:ch73-138e16.4, Drer\si:ch211-113e8.10, Drer\zgc:66443" "Scer\STP3, Scer\STP4, Scer\MIG2, Scer\MIG3, Scer\MIG1, Scer\ADR1" "Cele\klu-2, Cele\klu-1, Cele\odd-2" - "Mmus\Zfp91, Mmus\Zfp663, Mmus\Zfp811" "Hsap\ZFP91, Hsap\ZBTB14, Hsap\ZNF837, Hsap\ZNF543, Hsap\ZBTB7B, Hsap\ZBTB7A, Hsap\ZBTB7C" " larval stage | third instar , embryonic stage " " antennal disc | restricted

, eye disc | restricted

, wing vein L1 | presumptive

, tarsal segment | anlagen

, larval optic lobe | restricted

, morphogenetic furrow | posterior to

, dorsal prothoracic disc | restricted

, proneural cluster

, dorsal mesothoracic disc | restricted

, neuroblast

, scutum | presumptive

, scutellum | anlagen

, ventral thoracic disc | restricted

, larval brain | restricted

" " embryonic stage | stage 11 , embryonic stage , embryonic stage | stage >=10 , embryonic stage | stage 10,11 , embryonic stage | stage 9-11 , embryonic stage | early , embryonic stage | stage 16 " " neuroblast NB2-1

, neuroblast GP

, ventral nerve cord | restricted

, neuroblast

, neuroblast NB5-4

, ganglion mother cell GMC4-2b

, neuroblast NB2-5

, embryonic brain | restricted

, epidermis | restricted

, neuroblast NB5-6

, neuroblast NB2-4

, neuroblast NB4-1

, neuroblast NB5-5

, neuroblast NB4-2

, neuroblast NB1-1

, neuroblast NB7-1

, neuroblast NB7-4

, neuroblast NB6-1

, neuroblast NB7-2

, neuroblast NB5-3

, neuroblast NB4-3

, deuterocerebral neuroblast | subset

, embryonic/larval posterior spiracle

, neuroblast NB7-3

, neuroblast NB5-2

, neuroblast NB2-2

, neuroblast NB5-1

, neuroblast NB3-2

, neuroblast NB6-2

, neuroblast NB3-3

, protocerebral neuroblast | subset

, neuroblast NB3-1

, neuroblast NB1-2

, neuroblast NB3-5

, tritocerebral neuroblast | subset

, procephalic segment

, neuroblast NB4-4

" "neuroanatomy defective,somatic clone,visible,viable,feeding behavior defective,lethal,recessive,partially lethal - majority die,small body,increased cell number,tumorigenic,decreased cell size,decreased cell growth,decreased cell death,increased cell death" "rhabdomere R7,type II neuroblast,supernumerary,somatic clone,chaeta,external sensory organ precursor cell,presutural bristle,anterior supraalar bristle,presutural bristle precursor cell,supraalar bristle precursor cell,embryonic/larval neuroblast,anterior sternopleural bristle,macrochaeta,tarsal segment,tarsal segment 3,tarsal segment 4,tibia,pretarsus,ganglion mother cell GMC4-2b,RP2 motor neuron,abdominal 1 dorsal motor neuron,type I neuroblast,wing,ectopic,eye,adult head,interommatidial bristle,adult thorax,salivary gland,ommatidium,heat sensitive,trochanter,femur,metatarsus,distal,prothoracic leg sensillum,mesothoracic leg sensillum,metathoracic leg sensillum,sex comb,basal cylinder,wing margin bristle,abdominal 2 dorsal motor neuron,abdominal 3 dorsal motor neuron,abdominal 4 dorsal motor neuron,abdominal 5 dorsal motor neuron,abdominal 6 dorsal motor neuron,abdominal 7 dorsal motor neuron,antennal sense organ,subesophageal ganglion neuron,lens,retina,microchaeta,trichome of the posterior wing margin" DRSC11357 K -0.24081982 -0.027254007 -0.117318036 -0.371421181 1.232147288 1.541410538 FBgn0004394 pdm2 POU domain protein 2 http://flybase.org/reports/FBgn0004394 "FBgn0032441, FBgn0032443" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 DNA binding ; GO:0003677 | inferred from mutant phenotype transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" "ectoderm development ; GO:0007398 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype generation of neurons ; GO:0048699 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred by curator from GO:0006355 inferred from mutant phenotype "POU domain protein 2, pdm, pdm-2, CG12287, Pdm2, miti, Pdm-2, dPOU28, dPOU28/pdm-2, dpou28, dPOU-28, dim, dOct2, CG15487, CG15486, pdm2, Pdm, Oct-2, Oct2" "IPR017970:Homeobox, conserved site, IPR000327:POU-specific domain, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR010982:Lambda repressor-like, DNA-binding domain, IPR013847:POU domain" CG12287 11-Aug-17 DroID_v2017_08 "Drer\pou3f3a, Drer\pou2f3, Drer\pou1f1, Drer\pou3f3b, Drer\pou2f2a, Drer\pou5f3, Drer\pou6f1, Drer\pou3f2a, Drer\pou2f1a, Drer\zgc:109809, Drer\pou3f1, Drer\pou3f2b, Drer\pou2f1b" - "Cele\ceh-6, Cele\ceh-18" "Xtro\pou3f4, Xtro\pou1f1, Xtro\pou5f3.2, Xtro\pou3f1, Xtro\pou2f3, Xtro\pou5f3.1, Xtro\pou6f1, Xtro\pou6f2, Xtro\pou3f3" "Mmus\Pou5f1, Mmus\Pou6f2, Mmus\Pou2f2, Mmus\Pou3f2, Mmus\Pou2f1, Mmus\Ccdc160, Mmus\Pou3f4, Mmus\Pou6f1, Mmus\Pou3f1, Mmus\Pou3f3, Mmus\Pou2f3, Mmus\Pou5f2, Mmus\Pou1f1" "Hsap\POU5F1B, Hsap\POU2F2, Hsap\POU6F1, Hsap\POU5F2, Hsap\POU2F3, Hsap\POU3F1, Hsap\POU3F3, Hsap\POU2F1, Hsap\CCDC160, Hsap\POU3F4, Hsap\POU6F2, Hsap\POU1F1, Hsap\POU3F2, Hsap\POU5F1" " embryonic stage | late , embryonic stage , embryonic stage | gastrula , embryonic stage | mid , embryonic stage | mid-late , embryonic stage | cellular blastoderm , embryonic stage | stage 10 , embryonic stage | stage 6 , embryonic stage | early , embryonic stage | stage 9 , embryonic stage | stage 5 " " abdominal segment 8--9 &&of peripheral nervous system

, central nervous system | restricted

, abdominal dorsal multidendritic neuron

, neurogenic region

, larval labral segment sense organ

, scolopidial ligament cell &&of dorsal thoracic cluster &&of thoracic segment 2--3

, embryonic peripheral nervous system | restricted

, ectoderm | stripes

, embryonic/larval hindgut

, embryonic brain | restricted

, optic lobe

, embryonic central nervous system | restricted

, labral segment

, tracheal primordium

, scolopidial ligament cell &&of lateral abdominal cluster &&of abdominal segment 1--7

,

20-40% egg length ,

30-50% egg length , abdominal 1--7 dorsal bipolar neuron dbp

, neuroblast | restricted

, parasegment 7

, sensory neuron &&of embryonic/larval foregut

, embryonic neuron

,organism | segment polarity , larval labral segment sense organ | precursor

, dorsal thoracic bd1

, chordotonal organ &&of lateral thoracic cluster &&of prothoracic segment

, organism | odd pair rule

, larval brain

, organism | 20-50% egg length

,

segment polarity , hypophysis

, embryonic central nervous system | presumptive

, organism | 90-100% egg length

" embryonic stage | stage 11 ganglion mother cell GMC4-2a

"viable,fertile,lethal,heat sensitive,neuroanatomy defective" "RP2 motor neuron,ectopic,embryonic ganglion mother cell,neuroblast NB4-2,embryonic abdominal segment 2,ganglion mother cell,RP2sib neuron,heat sensitive,embryonic abdominal segment 6,larval abdominal segment 1,larval abdominal segment 2,larval abdominal segment 3,larval head,ganglion mother cell GMC4-2a,U5 neuron,supernumerary,U3 neuron,U4 neuron,neuroblast NB3-3" DRSC02496 EK -0.767183749 -0.260164455 -1.701163938 1.467915636 2.168064741 1.363649743 FBgn0000529 bsh brain-specific homeobox http://flybase.org/reports/FBgn0000529 FBgn0010392 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement neuron fate commitment ; GO:0048663 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype" nucleus ; GO:0005634 | non-traceable author statement inferred from direct assay "Bsh, lambdaE86, E86, Hox11-310, CG10604, bsh, BSH" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG10604 11-Aug-17 DroID_v2017_08 "Drer\nanog, Drer\vox, Drer\vent, Drer\bsx" - "Cele\tab-1, Cele\ceh-27, Cele\ceh-19, Cele\ceh-7, Cele\ceh-51, Cele\ceh-23, Cele\ceh-24" Xtro\bsx "Mmus\Bsx, Mmus\Nanog" "Hsap\VENTX, Hsap\NANOG, Hsap\BSX" " embryonic stage | >6hr , adult stage , larval stage | third instar , larval stage--adult stage " " lamina

, optic lobe

" embryonic stage | stage 11-16 supraesophageal ganglion | restricted

"viable,neuroanatomy defective,somatic clone" "medullary intrinsic neuron Mi1,somatic clone,transmedullary neuron,ectopic,lamina monopolar neuron L3,lamina monopolar neuron L4,supernumerary" FBgn0000808 gd gastrulation-defective http://flybase.org/reports/FBgn0000808 - protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence or structural similarity with HGNC:3551 serine-type peptidase activity ; GO:0008236 | non-traceable author statement serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues peptidase activity ; GO:0008233 | traceable author statement "dorsal/ventral axis specification ; GO:0009950 | traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | traceable author statement protein processing ; GO:0016485 | inferred from genetic interaction with ea dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | non-traceable author statement Toll signaling pathway ; GO:0008063 | inferred from genetic interaction with pip inferred from genetic interaction with Tl proteolysis ; GO:0006508 | traceable author statement dorsal/ventral axis specification ; GO:0009950 | inferred from genetic interaction with pip" extracellular region ; GO:0005576 | inferred from sequence or structural similarity "GD, SP186, fs(1)gd, fs(1)M18, fs(1)573, gas, fs(1)A573, fs(1)190-5, fs(1)18, CG1505, gd, Gd" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR031986:Serine protease gd, N-terminal domain" CG1505 11-Aug-17 DroID_v2017_08 "Drer\pamr1, Drer\masp1" - "Cele\try-5, Cele\svh-1" - - - " adult stage && oogenesis stage , adult stage && oogenesis stage | stage >S10 , embryonic stage | early " " nurse cell

, follicle cell

, oocyte

, ovary

" " adult stage && oogenesis stage , embryonic stage | early " ovary

"lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,lethal,maternal effect,female sterile,recessive,hyperplasia,heat sensitive,germline clone,non-rescuable maternal effect,partially,dorsal/ventral axis specification defective,viable" "embryonic/first instar larval cuticle,filzkorper,denticle belt,embryo,dorsal,gastrula embryo,maternal effect,amnioserosa,mesoderm,germline clone,neurogenic region,egg,ventral" FBgn0000715 FMRFa FMRFamide http://flybase.org/reports/FBgn0000715 - protein_coding_gene neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with FMRFaR hormone activity ; GO:0005179 | non-traceable author statement behavioral defense response ; GO:0002209 | inferred from direct assay negative regulation of heart rate ; GO:0010459 | inferred from direct assay adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype negative regulation of heart contraction ; GO:0045822 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay larval locomotory behavior ; GO:0008345 | inferred from direct assay positive regulation of neuromuscular synaptic transmission ; GO:1900075 | inferred from direct assay regulation of striated muscle contraction ; GO:0006942 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement extracellular space ; GO:0005615 | inferred by curator from GO:0071855 extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay "FMRFa, dFmrfa, DPKQDFMRF-amide, dFMRFa-1, FMRF, Drm-FMRFa4, Drm-FMRFa3, Drm-FMRFa2, Drm-FMRFa1, Drm-FMRF-5, Drm-FMRF-4, Drm-FMRF-3, Drm-FMRF-2, Drm-FMRF-1, dFMRFa, dFMRF, fmrf, DPKQDFMRFamide, CG2346, Fmrf, dFmrf, FMRFamide, FMRFa-like, FMRFa-1, FMRFa-2, FMRFa-3, FMRFa-4, FMRFa-5, FMRFa-6, FMRFa-7, FMRFa-8, dFMRFa-2, dFMRFa-3, dFMRFa-4, dFMRFa-5, dFMRFa-6, dFMRFa-7, dFMRFa-8, FmrF" IPR002544:FMRFamide-related peptide-like CG2346 11-Aug-17 DroID_v2017_08 - - "Cele\flp-6, Cele\flp-8, Cele\flp-3, Cele\flp-9, Cele\flp-13, Cele\flp-5, Cele\nlp-13, Cele\flp-18, Cele\flp-1, Cele\flp-14, Cele\flp-17, Cele\flp-7, Cele\flp-22" - - Hsap\RBM12B " embryonic stage | stage >=16 , larval stage , prepupal stage--adult stage , larval stage--adult stage , adult stage , embryonic stage | late " " neuron | subset

, central nervous system | restricted

" " prepupal stage--adult stage , embryonic stage | stage >=15 , larval stage " " central nervous system | restricted

, neuron | subset

" "lethal,viable" FBgn0004364 18w 18 wheeler http://flybase.org/reports/FBgn0004364 - protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity with Tl "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000157 antimicrobial humoral response ; GO:0019730 | NOT inferred from mutant phenotype multicellular organism development ; GO:0007275 | traceable author statement axis elongation ; GO:0003401 | inferred from genetic interaction with 18w, Tollo convergent extension ; GO:0060026 | inferred from genetic interaction with 18w, Tollo embryonic morphogenesis ; GO:0048598 | traceable author statement antibacterial humoral response ; GO:0019731 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from expression pattern ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from direct assay anatomical structure morphogenesis ; GO:0009653 | inferred from mutant phenotype antibacterial humoral response ; GO:0019731 | traceable author statement defense response ; GO:0006952 | traceable author statement eggshell formation ; GO:0030703 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with Tl "toll, 18W, CT25100, tlr, l(2)00053, CG8896, 18w, 18-w, Toll-2, 18-wheeler" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG8896 11-Aug-17 DroID_v2017_08 "Drer\tlr7, Drer\nrros, Drer\si:dkey-182i3.11, Drer\chad, Drer\chadlb, Drer\chadla, Drer\tlr3, Drer\tlr21" - "Cele\lron-9, Cele\pan-1, Cele\tol-1, Cele\lron-1, Cele\lron-2" "Xtro\chadl, Xtro\tlr7, Xtro\LOC100485164, Xtro\LOC100488097, Xtro\tlr3" "Mmus\Chadl, Mmus\Tlr9, Mmus\Tlr7, Mmus\Tlr13, Mmus\Tlr3, Mmus\Chad" "Hsap\CHADL, Hsap\CHAD, Hsap\TLR7, Hsap\TLR3, Hsap\TLR9" " embryonic stage | stage 11 , embryonic stage | stage >=12 , embryonic stage | stage >=14 , embryonic stage | stage 8 , embryonic stage | stage 15-16 , embryonic stage | stage 7-11 , embryonic stage | stage 5 , embryonic stage | stage 6-10 , embryonic stage | stage 12 , embryonic stage | stage 15,16 , embryonic stage -- adult stage , embryonic stage | stage 16 , embryonic stage | stage 15 " " embryonic central nervous system | primordium

, embryonic/larval dorsal vessel

, salivary gland body primordium

, dorsal mesothoracic disc | presumptive

, amnioproctodeal invagination

, ventral midline

, adult midgut

,

segment polarity , embryonic/larval pharynx | dorsal

, tracheal system

, embryonic/larval salivary gland

, tracheal pit

, organism | even pair rule

, cephalic furrow

, dorsal metathoracic disc | presumptive

, anal plate

, labral segment

, anal pad

, antennal sense organ

, embryonic/larval posterior spiracle

, embryonic/larval hindgut

, maxillary palp sense organ

, embryonic/larval anterior spiracle

" "lethal,recessive,partially lethal - majority die,wild-type,viable,some die during larval stage,lethal - all die before end of larval stage,immune response defective,visible,body color defective,some die during pupal stage" "eye,adult abdomen,macrochaeta,ectopic,wing,leg,ventral thoracic disc,wing disc,antenna,haltere,mesothoracic tergum" FBgn0003042 Pc Polycomb http://flybase.org/reports/FBgn0003042 "FBgn0015223, FBgn0052443" protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay methylated histone binding ; GO:0035064 | traceable author statement methylated histone binding ; GO:0035064 | inferred from direct assay core promoter binding ; GO:0001047 | inferred from direct assay "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from mutant phenotype inferred from genetic interaction with ph-p syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype negative regulation of response to gamma radiation ; GO:2001229 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype specification of segmental identity, abdomen ; GO:0007385 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from direct assay PRC1 complex ; GO:0035102 | traceable author statement PRC1 complex ; GO:0035102 | inferred from direct assay intercalary heterochromatin ; GO:0005725 | non-traceable author statement chromatin ; GO:0000785 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Pc, PC, CG32443, dPC, Pc-G, DmPc, CG7618, PcG, pc" "IPR017984:Chromo domain subgroup, IPR000953:Chromo/chromo shadow domain, IPR016197:Chromo domain-like, IPR033773:CBX family C-terminal motif, IPR023779:Chromo domain, conserved site, IPR023780:Chromo domain" CG32443 11-Aug-17 DroID_v2017_08 "Drer\cbx8b, Drer\cbx2, Drer\cbx4, Drer\cbx8a, Drer\cbx6b, Drer\cbx6a, Drer\cbx7b, Drer\nptxra, Drer\cbx7a" - "Cele\cec-1, Cele\cec-9" "Xtro\cbx4, Xtro\cbx2, Xtro\cbx7, Xtro\cbx6, Xtro\cbx8" "Mmus\Cbx4, Mmus\Cbx7, Mmus\Cbx8, Mmus\Cbx6, Mmus\Npcd, Mmus\Cbx2" "Hsap\CBX4, Hsap\CBX8, Hsap\CBX2, Hsap\CBX7, Hsap\CBX6" " egg stage | unfertilized egg , larval stage , embryonic stage | early , embryonic stage | late , embryonic stage | 0-8 hr , embryonic stage " " unfertilized egg

, embryonic/larval salivary gland

, embryonic central nervous system

,

ubiquitous " " embryonic stage , adult stage && oogenesis stage | stage S1-2 , adult stage && oogenesis stage | stage S10-14 , embryonic stage | early , adult stage && oogenesis stage | stage S9-14 , larval stage , adult stage && oogenesis stage " " thoracico-abdominal ganglion

, embryonic central nervous system

, egg chamber

, embryonic/larval pharynx

, embryonic/larval salivary gland

, subesophageal ganglion

, follicle cell

,

ubiquitous , nurse cell

, larval fat body | anterior

, germarium

, supraesophageal ganglion

" "visible,dominant,homeotic,mitotic cell cycle defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,heat sensitive,male,suppressor of variegation,non-suppressor of variegation,non-enhancer of variegation,neuroanatomy defective,somatic clone,decreased cell number,tumorigenic,wild-type" "mesothoracic leg,mesothoracic segment,sex comb,ectopic,metathoracic leg,abdominal segment,wing,mesothoracic leg & sex comb | ectopic,metathoracic leg & sex comb | ectopic,anaphase | embryonic stage,telophase | embryonic stage,leg,supernumerary,genital disc primordium,ventral mesothoracic disc primordium,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,antenna,presumptive embryonic/larval central nervous system,metathoracic leg & sex comb tooth | ectopic,mesothoracic leg & sex comb tooth | ectopic,midgut constriction,embryonic/larval brain,metathoracic segment,adult abdominal segment 1,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 6,male,prothoracic leg,abdominal segment 4,abdominal segment 5,female,haltere,embryonic thoracic segment,embryonic abdominal segment,abdominal tergite 4,sternopleural bristle,adult external mesothorax,adult external prothorax,gonadal sheath proper primordium,heat sensitive,larval segment,larval head,photoreceptor cell,somatic clone,eye,eye disc,morphogenetic furrow,embryonic head,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,larval abdominal segment 4,larval abdominal segment 5,dendrite | somatic clone,neuroblast,dendrite & dorsal multidendritic neuron ddaC | somatic clone,sex comb tooth" FBgn0001077 ftz fushi tarazu http://flybase.org/reports/FBgn0001077 FBgn0014176 protein_coding_gene "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" "central nervous system development ; GO:0007417 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype periodic partitioning by pair rule gene ; GO:0007366 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay cell fate specification ; GO:0001708 | traceable author statement blastoderm segmentation ; GO:0007350 | traceable author statement posterior head segmentation ; GO:0035289 | traceable author statement periodic partitioning by pair rule gene ; GO:0007366 | non-traceable author statement trunk segmentation ; GO:0035290 | traceable author statement" - "ftz, Dm-ftz, Dm-Ftz, l(3)84Ag, Ual, CG2047, BG:DS07876.1, Ftz, FTZ, DmFtz, Dmftz" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR005567:Fushi tarazu, N-terminal, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG2047 11-Aug-17 DroID_v2017_08 "Drer\gsx1, Drer\mnx1, Drer\hoxc8a, Drer\hoxb1b, Drer\hoxc3a, Drer\hoxa2b, Drer\hoxb6a, Drer\hoxb4a, Drer\hoxb2a, Drer\meox2a, Drer\meox1, Drer\hoxc4a, Drer\hoxc5a, Drer\hoxb7a, Drer\hoxa9b, Drer\hoxa3a, Drer\hoxb5b, Drer\hoxa1a, Drer\hoxa4a, Drer\hoxb3a, Drer\hoxd4a, Drer\hoxc6b, Drer\hoxc6a, Drer\hoxb8b, Drer\hoxb6b, Drer\pdx1, Drer\mnx2a, Drer\gsx2, Drer\hoxa5a, Drer\hoxb1a, Drer\hoxc1a, Drer\gbx2, Drer\hoxb5a, Drer\gbx1, Drer\hoxd3a, Drer\meox2b" "Scer\PHO2, Scer\YOX1, Scer\YHP1" "Cele\mab-5, Cele\lin-39" "Xtro\hoxb6, Xtro\mnx1, Xtro\hoxa3, Xtro\hoxb4, Xtro\gbx2.2, Xtro\hoxd3, Xtro\gsx1, Xtro\hoxb1, Xtro\hoxb2, Xtro\hoxa2, Xtro\gsx2, Xtro\hoxb8, Xtro\hoxb3, Xtro\hoxc5, Xtro\hoxb7, Xtro\hoxc3, Xtro\hoxc8, Xtro\hoxd1, Xtro\hoxc4, Xtro\hoxa5, Xtro\gbx2.1, Xtro\hoxb5, Xtro\hoxa1, Xtro\meox2, Xtro\pdx1, Xtro\hoxd8" "Mmus\Hoxb1, Mmus\Hoxd3, Mmus\Hoxb7, Mmus\Hoxa2, Mmus\Nkx6-2, Mmus\Hoxa1, Mmus\Gbx2, Mmus\Hoxb2, Mmus\Hoxd8, Mmus\Hoxb5, Mmus\Hoxc5, Mmus\Gbx1, Mmus\Hoxd1, Mmus\Hoxa5, Mmus\Hoxa6, Mmus\Hoxb8, Mmus\Hoxa7, Mmus\Pdx1, Mmus\Hoxc8, Mmus\Hoxc6, Mmus\Hoxb3, Mmus\Hoxa4, Mmus\Meox1, Mmus\Hoxa3, Mmus\Mnx1, Mmus\Gsx1, Mmus\Meox2, Mmus\Gsx2, Mmus\Hoxb6, Mmus\Hoxd4, Mmus\Hoxb4, Mmus\Hoxc4" "Hsap\HOXA7, Hsap\HOXD3, Hsap\HOXB2, Hsap\HOXB3, Hsap\HOXA5, Hsap\GBX1, Hsap\HOXA3, Hsap\HOXD1, Hsap\HOXC8, Hsap\NKX6-2, Hsap\HOXA6, Hsap\HOXB8, Hsap\GBX2, Hsap\HOXA1, Hsap\HOXC6, Hsap\MEOX1, Hsap\HOXC4, Hsap\HOXD8, Hsap\HOXB6, Hsap\HOXB7, Hsap\HOXD4, Hsap\MEOX2, Hsap\MNX1, Hsap\HOXA2, Hsap\PDX1, Hsap\HOXB5, Hsap\GSX2, Hsap\HOXB1, Hsap\HOXA4, Hsap\HOXC5, Hsap\HOXB4, Hsap\GSX1" " embryonic stage , embryonic stage | stage 4-12 , embryonic stage | 0-12hr , embryonic stage | stage 10 , embryonic stage | 2-4hr , embryonic stage | stage 3 , embryonic stage | early , embryonic stage | cellular blastoderm , embryonic stage | stage 4-14 " " parasegment 12 | pair rule

, ventral nerve cord | pair rule

,

odd pair rule ,

20-70% egg length , parasegment 14 | pair rule

, parasegment 2 | pair rule

, parasegment 8 | pair rule

, parasegment 4 | pair rule

, parasegment 2,4,6,8,10,12,14 , parasegment 10 | pair rule

, parasegment 6 | pair rule

" " embryonic stage | cellular blastoderm , embryonic stage | stage 10-12 , embryonic stage | stage 4-12 , embryonic stage | stage 4 , embryonic stage | 12-15hr , embryonic stage | 3-5hr , embryonic stage | stage 11,12 , embryonic stage | 5-6hr , embryonic stage | stage 10 , embryonic stage | stage >9 , embryonic stage | blastoderm , embryonic stage , embryonic stage | 3-14hr , embryonic stage | stage 5 , embryonic stage | stage 4-8 " "

pair rule , MP1b neuron

, parasegment 4 | pair rule

, parasegment 12 | pair rule

, parasegment 4

, embryonic/larval hindgut

, RP2 neuron

, parasegment 2

,

odd pair rule , dMP2 neuron

, embryonic central nervous system | restricted

, neuroblast MP2

, parasegment 14

, pole cell | anterior to

, parasegment 6

, embryonic/larval proventriculus

, parasegment 8

, MP1 neuron

, parasegment 6 | pair rule

, aCC neuron

, parasegment 10

, embryonic central nervous system | segmentally repeated

, RP1 neuron

, pCC neuron

, parasegment 10 | pair rule

, parasegment 2 | pair rule

, glioblast

, ganglion mother cell GMC1-1a

, organism | 70-90% egg length

, parasegment 14 | pair rule

, parasegment 8 | pair rule

, organism | pair rule

, vMP2 neuron

, MP1a neuron

, parasegment 12

" "lethal,recessive,pair rule phenotype,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,heat sensitive,viable,female,visible,dominant,partially,homeotic,increased cell death" "dorsal closure embryo,presumptive embryonic/larval central nervous system,hypostomal sclerite,parasegment 1,parasegment 2,embryonic labial segment,embryonic maxillary segment,embryonic epidermis,presumptive embryonic/larval nervous system,denticle belt,parasegment 10,parasegment 12,parasegment 14,parasegment 4,parasegment 6,parasegment 8,embryonic abdomen,embryonic thorax,prothoracic ventral denticle belt,metathoracic ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic segment,heat sensitive,embryonic/first instar larval cuticle,parasegment 3,parasegment 5,parasegment,embryo,segment,parasegment 7,parasegment 9,parasegment 11,parasegment 13,parasegment 15,adult abdominal segment 2,adult abdominal segment 4,larval segment,haltere,wing,ectopic,Keilin's organ,metathoracic Keilin's organ,adult abdominal segment 1,adult abdominal segment 3,posterior,adult abdomen,adult mesothoracic segment,adult metathoracic segment,anterior,abdominal segment 1,abdominal segment 3,abdominal segment 5,abdominal segment 7,gonadal sheath proper primordium,fat body/gonad primordium,extended germ band embryo,embryonic abdominal segment 2,embryonic abdominal segment 4,embryonic abdominal segment 6,embryonic abdominal segment 8,abdominal segment 4,tergite,mesothoracic ventral denticle belt,abdominal 1 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal tergite 1,arista,third segment of antenna,antennal segment 3 & bract | ectopicDll-md23,antenna,T1 beard,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic head,leg,tarsal segment 3,tarsal segment 4,mesothoracic tibia,mesothoracic tibial apical bristle,pretarsus,antennal disc,distal,prothoracic segment,embryonic abdominal segment 1" FBgn0000075 amd alpha methyl dopa-resistant http://flybase.org/reports/FBgn0000075 FBgn0032757 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR002129 deaminase activity ; GO:0019239 | inferred from direct assay carboxy-lyase activity ; GO:0016831 | non-traceable author statement carboxy-lyase activity ; GO:0016831 | inferred from direct assay cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010977 catecholamine metabolic process ; GO:0006584 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype - "CG10501, X04695, l(2)amd alpha-methyldopa hypersensitive, l(2)amd, fAMD, l(2)amd[H], l(2)37Bk, CG17345, amd, AMD-r" "IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase, IPR002129:Pyridoxal phosphate-dependent decarboxylase, IPR010977:Aromatic-L-amino-acid decarboxylase, IPR021115:Pyridoxal-phosphate binding site" CG10501 11-Aug-17 DroID_v2017_08 "Drer\hdc, Drer\ddc" - "Cele\basl-1, Cele\bas-1, Cele\tdc-1, Cele\hdl-1" "Xtro\ddc, Xtro\hdc" "Mmus\Ddc, Mmus\Hdc" "Hsap\DDC, Hsap\HDC" " embryonic stage | stage >12 , larval stage , embryonic stage | stage >11 , embryonic stage | stage 8 , larval stage | third instar , embryonic stage | stage >=16 , embryonic stage | stage 5 , embryonic stage | stage >=15 , embryonic stage | stage 4 " " embryonic/larval proventriculus

, imaginal disc

, anal pad

, embryonic/larval esophagus

, ventral nerve cord

, stomodeum | primordium

, eye-antennal disc

, ventral thoracic disc

, proctodeum

, embryonic/larval tracheal system

, ring gland

, lymph gland

, embryonic/larval hindgut

, larval brain

, embryonic/larval pharynx | anlagen

, dorsal mesothoracic disc

, epidermis

, embryonic/larval pharynx | dorsal

, embryonic/larval foregut

, Malpighian tubule primordium

, embryo | dorsal

" "lethal,recessive,wild-type,partially,chemical sensitive,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage,viable" "cuticle,anal pad,anal slit" FBgn0039286 dan distal antenna http://flybase.org/reports/FBgn0039286 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O18381 inferred from physical interaction with UniProtKB:Q24027 inferred from physical interaction with UniProtKB:Q9VBW9" "segment specification ; GO:0007379 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype antennal development ; GO:0007469 | inferred from mutant phenotype central nervous system formation ; GO:0021556 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Dan, CG11849, dan, fer" "IPR009057:Homeobox domain-like, IPR007889:DNA binding HTH domain, Psq-type, IPR011991:Winged helix-turn-helix DNA-binding domain" CG11849 11-Aug-17 DroID_v2017_08 - - - - - - " pupal stage | early , larval stage | third instar " " eye-antennal disc | restricted

, antennal disc | restricted & central

, eye disc | restricted

" "viable,visible,neuroanatomy defective,lethal" "embryonic/larval hemocyte | third instar larval stage,antennal segment 3 & macrochaeta | ectopic,unguis,antenna,third segment of antenna,leg,distal,arista,ectopic,antennal segment 3 & macrochaeta | ectopicDll-md23,eye,ommatidium,interommatidial bristle,ventral nerve cord,presumptive embryonic/larval nervous system,germ band,rostral membrane,wing,wing margin bristle,wing hinge" FBgn0013973 Gycbeta100B Guanylyl cyclase beta-subunit at 100B http://flybase.org/reports/FBgn0013973 - protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR011644 guanylate cyclase activity ; GO:0004383 | inferred from direct assay "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 cGMP biosynthetic process ; GO:0006182 | traceable author statement cGMP biosynthetic process ; GO:0006182 | inferred from direct assay signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from direct assay" "CG1470, Gycbeta-100B, Dgc beta 1, dgcb1, dgcbeta1, Gycbeta100B, sGCbeta100B, gycbeta100B, Dgcbeta1, sGCbeta1, Gbeta100B" "IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR011644:Heme-NO binding, IPR024096:NO signalling/Golgi transport ligand-binding domain, IPR029787:Nucleotide cyclase, IPR011645:Haem NO binding associated" CG1470 11-Aug-17 DroID_v2017_08 "Drer\gucy1a3, Drer\gucy1b2, Drer\gucy1a2, Drer\gucy1b3" - "Cele\gcy-36, Cele\gcy-34, Cele\gcy-33, Cele\gcy-32, Cele\gcy-35, Cele\gcy-31, Cele\gcy-37" "Xtro\gucy1a2, Xtro\gucy1b3" "Mmus\Gucy1a3, Mmus\Gucy1b2, Mmus\Gucy1a2, Mmus\Gucy1b3" "Hsap\GUCY1A2, Hsap\GUCY1B3, Hsap\GUCY1A3" adult stage adult head

adult stage " optic lobe

, neuropil

" "viable,fertile" FBgn0022984 qkr58E-3 quaking related 58E-3 http://flybase.org/reports/FBgn0022984 FBgn0025581 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence model RNA binding ; GO:0003723 | inferred from direct assay "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype inferred from genetic interaction with rpr inferred from physical interaction with Dredd" nucleus ; GO:0005634 | inferred from direct assay nuclear speck ; GO:0016607 | inferred from direct assay "kep1, KEP1, qrk58E-3, CG3584, qkr58E-3, qkr58e-3, QKR58E-3" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG3584 11-Aug-17 DroID_v2017_08 "Drer\khdrbs1b, Drer\qkia, Drer\khdrbs1a, Drer\khdrbs3, Drer\qkib, Drer\qki2, Drer\khdrbs2" Scer\MSL5 "Cele\F54D1.1, Cele\asd-2, Cele\gld-1, Cele\K07H8.9, Cele\Y57G11C.36, Cele\B0280.11, Cele\sfa-1" "Xtro\khdrbs1, Xtro\qki, Xtro\khdrbs2, Xtro\khdrbs3" "Mmus\Sf1, Mmus\Khdrbs1, Mmus\Khdrbs3, Mmus\Khdrbs2, Mmus\Qk" "Hsap\KHDRBS2, Hsap\QKI, Hsap\SF1, Hsap\KHDRBS3, Hsap\KHDRBS1" " adult stage | male , embryonic stage -- adult stage " "male fertile,viable,female fertile,partially,immune response defective" "egg,dorsal appendage,eye,ectopic" FBgn0002629 E(spl)m4-BFM "Enhancer of split m4, Bearded family member" http://flybase.org/reports/FBgn0002629 - protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with neur protein binding ; GO:0005515 | inferred from physical interaction with neur sensory organ development ; GO:0007423 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype nucleus ; GO:0005634 | traceable author statement "CG6099, HLHm4, E(spl)m4, m4, DmelCG6099, E(spl)m4-BFM, E(spl) m4" IPR029686:Enhancer of split M4 family CG6099 11-Aug-17 DroID_v2017_08 - - - - - - " larval stage | third instar , embryonic stage | stage 11-12 , embryonic stage | stage 5 , embryonic stage | stage 11 , P | stage P4 , embryonic stage | 2-10 hr , embryonic stage | stage 8-17 , embryonic stage | stage 10 , embryonic stage | stage 7-11 , embryonic stage | stage 6,7 , embryonic stage | stage >7 , embryonic stage | stage 11-14 " " proneural cluster &&of ventral thoracic disc

, mesoderm

, proneural cluster | presumptive

, dorsal mesothoracic disc

, vitellophage

, epidermis | restricted

, ventral thoracic disc

, sensillum campaniformium &&of wing

, proneural cluster &&of eye disc

, ventral neurogenic region

, morphogenetic furrow | anterior to

, posterior midgut proper primordium

, ectoderm

, mesectoderm

, supraesophageal ganglion

, proneural cluster &&of dorsal mesothoracic disc

, eye disc

, organism | striped

, stomatogastric nervous system | primordium

, optic lobe | primordium

" "visible,somatic clone" "macrochaeta,ectopic,sensory mother cell,scutellar bristle,campaniform sensillum of anterior crossvein,sensillum campaniformium,microchaeta,dorsal row & sensory mother cellap-md544,precursor,sensillum campaniformium of dorsal radius,somatic clone,central nervous system,peripheral nervous system,eye,ommatidium,lens,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B,head bristle" FBgn0004108 Nrt Neurotactin http://flybase.org/reports/FBgn0004108 - protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 axonogenesis ; GO:0007409 | inferred from genetic interaction with Abl axonal fasciculation ; GO:0007413 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from genetic interaction with Nrg axonogenesis ; GO:0007409 | inferred from mutant phenotype basolateral plasma membrane ; GO:0016323 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity basolateral plasma membrane ; GO:0016323 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | "dab, Nrt, BP106, Nrt BP106, Dab, nrt, Neur, neu, MabBP106, DAB, l(3)73Be, CG9704, BcDNA:LD22004, NRT, NT, NRT BP106" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR029058:Alpha/Beta hydrolase fold" CG9704 11-Aug-17 DroID_v2017_08 "Drer\nlgn4b, Drer\nlgn2b, Drer\nlgn2a, Drer\ces2, Drer\nlgn3b, Drer\nlgn1, Drer\si:ch211-93f2.1, Drer\nlgn4a, Drer\cell, Drer\cel.1, Drer\ces3, Drer\nlgn3a, Drer\si:ch211-71n6.4" - Cele\ges-1 "Xtro\LOC100494782, Xtro\nlgn2, Xtro\ces3, Xtro\nlgn4x, Xtro\nlgn3, Xtro\cel, Xtro\ces2" "Mmus\Ces2a, Mmus\Ces1b, Mmus\Ces1c, Mmus\Nlgn1, Mmus\Ces1e, Mmus\Ces2f, Mmus\Cel, Mmus\Nlgn2, Mmus\Ces3b, Mmus\Ces2h, Mmus\Ces3a, Mmus\Ces4a, Mmus\Ces2e, Mmus\Ces1d, Mmus\Ces5a, Mmus\Ces2c, Mmus\Ces1g, Mmus\Ces1h, Mmus\Ces2g, Mmus\Ces2b, Mmus\Nlgn3, Mmus\Ces1f" "Hsap\CES1, Hsap\CES3, Hsap\NLGN4X, Hsap\NLGN3, Hsap\CES2, Hsap\CES4A, Hsap\CEL, Hsap\CES5A, Hsap\NLGN2, Hsap\NLGN1, Hsap\NLGN4Y" " embryonic stage | early , embryonic stage , embryonic stage | stage >=9 , embryonic stage | stage 5 , embryonic stage && pupal stage && adult stage , embryonic stage && pupal stage , embryonic stage && adult stage , larval stage | third instar , embryonic stage | cellular blastoderm " " fat body primordium

, embryonic central nervous system | presumptive

, embryonic nervous system

, organism | 40-90% egg length dorsal

, embryonic peripheral nervous system | restricted

,

10-90% egg length ventral " " embryonic stage , embryonic stage | stage 5-7 , larval stage | third instar , embryonic stage | stage 12-16 , embryonic stage | stage 13-16 , embryonic stage | embryonic cycle 14 , embryonic stage | cellular blastoderm , embryonic stage -- adult stage , pupal stage , embryonic stage | embryonic cycle 13 , embryonic stage | stage 7 , embryonic stage | stage 10-17 , embryonic stage | stage 5 , embryonic stage | stage 5-10 , larval stage , embryonic stage | stage 16 , embryonic stage | stage 13-17 , embryonic stage | stage >=9 " " multidendritic neuron

, anterior transverse furrow

, photoreceptor cell

, embryonic central nervous system

, visceral mesoderm

, cell body

, neuroblast

,

10-90% egg length ventral , photoreceptor cell

, larval central nervous system

, cephalic furrow

, sensory neuron &&of wing

, fat body primordium

, embryonic peripheral nervous system | restricted

, ventral furrow

, anterior midgut proper primordium

, embryonic nervous system

, dorsal vessel primordium

, organism | 40-90% egg length & dorsal

, mesoderm

, eye-antennal disc | restricted

, dorsal mesothoracic disc | restricted

, dorsal fold

, posterior transverse furrow

, larval optic lobe

, neuron &&of ocellus

, ventral thoracic disc

, ventral nerve cord commissure

, ventral nerve cord

, eye-antennal disc

, supraesophageal ganglion

, embryonic central nervous system | presumptive

, amnioserosa

, neuron

" "viable,fertile,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective" "ocellar nerve,ventral nerve cord,axon | embryonic stage,presumptive embryonic/larval central nervous system,eye photoreceptor cell,somatic clone,ommatidium,photoreceptor cell R7,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,commissure" FBgn0039581 Moca-cyp Moca-cyp http://flybase.org/reports/FBgn0039581 protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from direct assay "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG1866, BEST:LD38313, anon-WO0147981.5, anon-WO0147981.4, anon-WO0147981.13, Moca-cyp, moca" "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG1866 11-Aug-17 DroID_v2017_08 "Drer\ppil6, Drer\ppiab, Drer\si:ch1073-55a19.2, Drer\ppig, Drer\LOC100333141, Drer\ppie, Drer\ppiaa, Drer\nktr, Drer\ppib, Drer\ppih, Drer\ppid" "Scer\CPR7, Scer\CPR6" "Cele\cyn-9, Cele\cyn-6, Cele\cyn-5, Cele\Y17G9B.4, Cele\cyn-8, Cele\cyn-11, Cele\cyn-1, Cele\cyn-2, Cele\cyn-3" "Xtro\ppie, Xtro\ppid, Xtro\ppic, Xtro\ppil6, Xtro\ppia, Xtro\ppib, Xtro\nktr, Xtro\ranbp2, Xtro\ppih" "Mmus\Ppia, Mmus\Ppig, Mmus\Ppie, Mmus\Ppib, Mmus\Ppid, Mmus\Ppif, Mmus\Nktr, Mmus\Ppil6, Mmus\Ppih, Mmus\Ranbp2, Mmus\Ppic" "Hsap\PPIG, Hsap\RGPD4, Hsap\PPIAL4G, Hsap\NKTR, Hsap\RGPD5, Hsap\PPIAL4D, Hsap\LOC105371242, Hsap\PPIAL4A, Hsap\PPIB, Hsap\RGPD3, Hsap\PPIA, Hsap\RGPD8, Hsap\RGPD1, Hsap\RGPD6, Hsap\RANBP2, Hsap\PPIF, Hsap\PPIE, Hsap\PPIH, Hsap\RGPD2, Hsap\PPIAL4C, Hsap\PPIL6, Hsap\PPID, Hsap\PPIC, Hsap\DSPP" " embryonic stage | stage 6-10 , embryonic stage | stage 8-13 , embryonic stage | stage 5 , embryonic stage | stage 1-4 , embryonic stage | stage 15 " " mesoderm

, embryonic central nervous system

, organism

,

, anterior embryonic/larval midgut && posterior embryonic/larval midgut

, ventral nerve cord && hindgut

" " embryonic stage | 2-21 hr , embryonic stage | stage 9-11 , embryonic stage | stage >5 , embryonic stage | 9-24 hr , embryonic stage | stage 1-7 , embryonic stage | stage >13 " " mesoderm

, organism

, anterior embryonic/larval midgut && posterior embryonic/larval midgut

,

, ventral nerve cord && hindgut && pharynx && proventriculus

, embryonic central nervous system

" "viable,fertile" FBgn0265998 Doa Darkener of apricot http://flybase.org/reports/FBgn0265998 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay" "compound eye photoreceptor development ; GO:0042051 | inferred from expression pattern inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype MAPK cascade ; GO:0000165 | NOT inferred from genetic interaction with rl inferred from genetic interaction with sev inferred from genetic interaction with sina inferred from genetic interaction with svp protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern negative regulation of MyD88-dependent toll-like receptor signaling pathway ; GO:0034125 | inferred from mutant phenotype negative regulation of male germ cell proliferation ; GO:2000255 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern brain morphogenesis ; GO:0048854 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype sex differentiation ; GO:0007548 | inferred from mutant phenotype inferred from genetic interaction with tra inferred from genetic interaction with tra2" nucleus ; GO:0005634 | inferred by curator from GO:0000381 cytoplasm ; GO:0005737 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "l(3)s2784, 0844/02, l(3)S084402, Doa, CG31049, CG33204, CG42320, CG33553, CG1658, DOA, DOA/CLK2, doa, Msu, l(3)01705" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain" CG42320 11-Aug-17 DroID_v2017_08 "Drer\clk2b, Drer\clk4a, Drer\clk4b, Drer\clk2a" Scer\KNS1 "Cele\Y73B3A.16, Cele\madd-3, Cele\Y111B2A.1, Cele\C16A11.10" "Xtro\clk2, Xtro\clk3, Xtro\clk1" "Mmus\Clk2, Mmus\Clk4, Mmus\Clk1, Mmus\Clk3" "Hsap\CLK4, Hsap\CLK1, Hsap\CLK2, Hsap\PPIL3, Hsap\CLK3" " embryonic stage | stage 13-17 , adult stage , embryonic stage | stage >=1 , embryonic stage | stage 13 , embryonic stage | early , embryonic stage | stage 10-11 , embryonic stage -- adult stage , oogenesis stage && adult stage | female , larval stage | late third instar larval stage , embryonic stage , larval stage | third instar , pupal stage " " ventral nerve cord

, embryonic brain | surrounding

, mesoderm

, adult thorax && adult abdomen

, ovary

, adult head

, eye-antennal disc

, embryonic brain

, labral segment

, procephalic segment

, ectoderm

, visceral mesoderm | surrounding

, embryonic/larval tracheal pit

, dorsal mesothoracic disc

, embryonic optic lobe

" " adult stage , embryonic stage | early , embryonic stage | stage 10-11 , larval stage , larval stage | late third instar larval stage , pupal stage | 0-24 hr , embryonic stage | stage 13-17 , embryonic stage | 0-24 hr , larval stage | third instar , embryonic stage " " ovary

, mesoderm

, larval salivary gland

, adult head

, embryonic/larval fat body

, embryonic central nervous system

, ectoderm

, eye-antennal disc

, Bolwig's nerve

,

ubiquitous , embryonic brain

" FBgn0011286 RyR Ryanodine receptor http://flybase.org/reports/FBgn0011286 "FBgn0010268, FBgn0022194" protein_coding_gene "ryanodine-sensitive calcium-release channel activity ; GO:0005219 | inferred from electronic annotation with InterPro:IPR009460, InterPro:IPR013333 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN001416417 ryanodine-sensitive calcium-release channel activity ; GO:0005219 | traceable author statement" calcium ion transport ; GO:0006816 | traceable author statement muscle contraction ; GO:0006936 | inferred from mutant phenotype response to anesthetic ; GO:0072347 | inferred from mutant phenotype heart contraction ; GO:0060047 | inferred from mutant phenotype regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype release of sequestered calcium ion into cytosol ; GO:0051209 | inferred from biological aspect of ancestor with PANTHER:PTN001416417 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009460 microtubule associated complex ; GO:0005875 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001416417 integral component of membrane ; GO:0016021 | non-traceable author statement "RyR, Ryr, l(2)k04913, RYR, ryr, dry, l(2)k00424, CG10844, DRY, DRR, dya, Rya-r76CD, D-RyR, Rya-r44F, Rya-R44F, dRyR, dRyr, rya-r44F, RyRs, Rya-44F" "IPR015925:Ryanodine receptor-related, IPR000699:RIH (RyR and IP3R Homology) domain, IPR003032:Ryanodine receptor Ryr, IPR003877:SPRY domain, IPR005821:Ion transport domain, IPR009460:Ryanodine Receptor TM 4-6, IPR011992:EF-hand domain pair, IPR013333:Ryanodine receptor, IPR013662:RyR/IP3R Homology associated domain, IPR001870:B30.2/SPRY domain, IPR014821:Inositol 1,4,5-trisphosphate/ryanodine receptor, IPR016093:MIR motif, IPR013320:Concanavalin A-like lectin/glucanase domain" CG10844 11-Aug-17 DroID_v2017_08 "Drer\ryr1a, Drer\ryr2a, Drer\ryr1b, Drer\ryr3, Drer\ryr2b" - Cele\unc-68 Xtro\ryr1 "Mmus\Ryr3, Mmus\Ryr2, Mmus\Ryr1" "Hsap\RYR1, Hsap\RYR3, Hsap\RYR2" " adult stage , embryonic stage | stage >=10 , embryonic stage | stage >=9 , embryonic stage , embryonic stage | stage 14 , embryonic stage | 6-12 hr , larval stage | second instar , larval stage | third instar " " adult brain

, proboscis muscle

, skeletal muscle of head

, mesoderm

, subesophageal ganglion

, skeletal muscle of leg

, mesothoracic extracoxal depressor muscle 66

, larval muscle system

, embryonic/larval hypodermal muscle

, embryonic/larval visceral muscle

, somatic muscle

, embryonic central nervous system

" "viable,chemical resistant,semidominant,locomotor behavior defective,lethal,chemical sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,recessive,feeding behavior defective" "RP2 motor neuron,embryonic/larval muscle system,larva,larval head,embryonic/larval visceral muscle,embryonic/larval dorsal vessel,adult heart,presumptive embryonic/larval muscle system" FBgn0260642 Antp Antennapedia http://flybase.org/reports/FBgn0260642 protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "anterior/posterior axis specification ; GO:0009948 | traceable author statement neuroblast development ; GO:0014019 | inferred from mutant phenotype specification of segmental identity, thorax ; GO:0007384 | traceable author statement specification of segmental identity, thorax ; GO:0007384 | inferred from mutant phenotype anterior/posterior axis specification ; GO:0009948 | inferred from mutant phenotype lymph gland development ; GO:0048542 | inferred from mutant phenotype midgut development ; GO:0007494 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype muscle cell fate specification ; GO:0042694 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from expression pattern specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Antp, Hu, ANTP, antp, AntP1, CG1028, ANT-C, Scx, DmAntp, DMANTPE1, Ant, Antp1, ANT-P, 3.4, AntP, DRO15DC96Z, l(3)84Ba, Ns, BG:DS07700.1, ANTC, Aus, Antp P1, Antp P2" "IPR017970:Homeobox, conserved site, IPR017995:Homeobox protein, antennapedia type, IPR001356:Homeobox domain, IPR001827:Homeobox protein, antennapedia type, conserved site, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa, IPR011989:Armadillo-like helical" CG1028 11-Aug-17 DroID_v2017_08 "Drer\hoxb3a, Drer\hoxb8b, Drer\hoxc1a, Drer\hoxc4a, Drer\hoxc8a, Drer\hoxb1b, Drer\hoxb7a, Drer\mnx1, Drer\hoxb2a, Drer\gsx2, Drer\hoxb1a, Drer\hoxb6a, Drer\hoxc5a, Drer\hoxb4a, Drer\hoxb8a, Drer\meox1, Drer\meox2a, Drer\hoxa1a, Drer\pdx1, Drer\gbx2, Drer\hoxd3a, Drer\hoxa9b, Drer\hoxb6b, Drer\cdx1b, Drer\hoxb5a, Drer\hoxd4a, Drer\meox2b, Drer\hoxc6a, Drer\hoxc6b, Drer\gsc, Drer\mnx2a, Drer\pou3f1, Drer\hoxa3a, Drer\hoxa2b, Drer\gbx1, Drer\pou3f3b, Drer\pou3f2b, Drer\hoxa5a, Drer\hoxa4a, Drer\hoxc3a, Drer\hoxb5b, Drer\lmx1bb, Drer\lmx1a, Drer\gsx1, Drer\lmx1ba" "Scer\PHO2, Scer\YOX1, Scer\YHP1" "Cele\php-3, Cele\ceh-6, Cele\lin-39, Cele\mab-5, Cele\lim-6, Cele\ceh-51" "Xtro\hoxb3, Xtro\hoxa2, Xtro\gbx2.2, Xtro\gsc, Xtro\hoxa1, Xtro\hoxb2, Xtro\meox2, Xtro\hoxb6, Xtro\hoxa5, Xtro\gsx2, Xtro\hoxc4, Xtro\gbx2.1, Xtro\hoxd3, Xtro\hoxd1, Xtro\hoxd8, Xtro\hoxb1, Xtro\hoxb7, Xtro\hoxb5, Xtro\hoxa6, Xtro\gsx1, Xtro\hoxa7, Xtro\hoxc6, Xtro\hoxb8, Xtro\hoxa3, Xtro\pou3f1, Xtro\hoxc8, Xtro\pdx1, Xtro\hoxc3, Xtro\hoxc5, Xtro\hoxb4, Xtro\mnx1" "Mmus\Hoxd3, Mmus\Pdx1, Mmus\Meox1, Mmus\Hoxd8, Mmus\Meox2, Mmus\Hoxb8, Mmus\Hoxa1, Mmus\Lmx1a, Mmus\Hoxa6, Mmus\Hoxb1, Mmus\Gbx1, Mmus\Hoxc4, Mmus\Mnx1, Mmus\Hoxd1, Mmus\Hoxd4, Mmus\Pou3f4, Mmus\Hoxc6, Mmus\Pou3f3, Mmus\Hoxa2, Mmus\Hoxa7, Mmus\Gbx2, Mmus\Hoxb4, Mmus\Hoxb3, Mmus\Hoxb5, Mmus\Hoxa5, Mmus\Gsx2, Mmus\Gsx1, Mmus\Hoxb7, Mmus\Hoxb2, Mmus\Hoxc8, Mmus\Hoxc5, Mmus\Lmx1b, Mmus\Hoxa4, Mmus\Hoxb6, Mmus\Pou3f2, Mmus\Pou3f1, Mmus\Hoxa3" "Hsap\LMX1A, Hsap\HOXB7, Hsap\HOXC6, Hsap\HOXA5, Hsap\HOXC8, Hsap\HOXB6, Hsap\LMX1B, Hsap\MEOX1, Hsap\HOXA2, Hsap\HOXA6, Hsap\POU3F3, Hsap\HOXC5, Hsap\HOXA1, Hsap\GSX1, Hsap\GSC2, Hsap\HOXB5, Hsap\HOXC4, Hsap\PDX1, Hsap\HOXB4, Hsap\HOXB2, Hsap\HOXB3, Hsap\HOXA7, Hsap\HOXB8, Hsap\MNX1, Hsap\POU3F4, Hsap\GSX2, Hsap\HOXA4, Hsap\HOXD3, Hsap\POU3F2, Hsap\HOXD4, Hsap\GBX1, Hsap\POU3F1, Hsap\HOXD1, Hsap\GBX2, Hsap\HOXB1, Hsap\HOXD8, Hsap\HOXA3, Hsap\MEOX2" " larval stage | third instar , larval stage , embryonic stage , embryonic stage | stage >=11 , embryonic stage | blastoderm , pupal stage , embryonic stage | late , embryonic stage--pupal stage , embryonic stage | mid , embryonic stage | stage 17 , embryonic stage | early , embryonic stage | stage 8 , embryonic stage | stage 11-17 , embryonic stage | stage 13 , embryonic stage | stage 1-11 " " dorsal mesothoracic disc | anterior

, dorsal prothoracic disc

, ectoderm

, embryonic central nervous system

, ventral mesothoracic disc

, dorsal mesothoracic disc | restricted

, ventral nerve cord

, parasegment 14 | primordium

, embryonic/larval midgut

, dorsal metathoracic disc

, dorsal mesothoracic disc

, larval brain

, visceral mesoderm &&of anterior embryonic/larval midgut

, ventral prothoracic disc

, parasegment 4--12

, ventral metathoracic disc

, embryonic/larval aorta | vicinity of

, parasegment 6 | primordium

, embryonic/larval muscle system

, ventral mesothoracic disc | anterior

, organism | 60% egg length

, organism | 40-60% egg length

, embryonic/larval somatic muscle

, embryonic mesothoracic segment

, dorsal metathoracic disc | restricted

, mesoderm &&of parasegment 4--6

, embryonic central nervous system | restricted

, embryonic/larval anterior spiracle | vicinity of

, dorsal prothoracic disc | restricted

, ectoderm &&of parasegment 3--14

" " embryonic stage , larval stage , larval stage | third instar , embryonic stage | late , embryonic stage | stage 13-14 , embryonic stage | stage >12 , embryonic stage | stage 13-17 , embryonic stage | stage 16 , embryonic stage | mid-late , embryonic stage | stage >=12 , embryonic stage | stage 8 , embryonic stage | stage 12-13 " " visceral mesoderm

{ 0 hb* } , ventral thoracic disc

, ectoderm

, visceral mesoderm

{ $ kni* } , imaginal disc

, cardioblast &&of embryonic metathoracic segment

, visceral mesoderm &&of parasegment 5--6 &&of embryonic/larval midgut

, embryonic mesothoracic segment

, visceral mesoderm

{ 0 prd* } , visceral mesoderm

{ 0 wg* } , visceral mesoderm

{ - ftz*/prd* } , embryonic central nervous system

, visceral mesoderm

{ 0 odd*/eve* } , visceral mesoderm

, parasegment 5 | visceral mesoderm

, dorsal mesothoracic disc | restricted

, embryonic prothoracic segment

, midgut constriction 1 | posterior

, ventral prothoracic disc | posterior

, visceral mesoderm

{ - opa*/prd* } , visceral mesoderm

{ 0 opa* } , embryonic abdominal neuromere

, visceral mesoderm

{ 0 h* } , visceral mesoderm

{ - Kr* } , peripodial epithelium

, embryonic prothoracic neuromere

, parasegment 5 &&of visceral mesoderm

, cardioblast &&of embryonic abdominal segment 2

, embryonic metathoracic segment

, ventral nerve cord

, embryonic mesothoracic neuromere

, embryonic metathoracic neuromere

, visceral mesoderm

{ 0 run* } , ventral metathoracic disc | anterior

, visceral mesoderm

{ 0 en* } , cardioblast && embryonic pericardial cell &&of embryonic abdominal segment 1

, embryonic abdominal segment 1--7

, embryonic peripheral nervous system | restricted

, parasegment 4--6

, visceral mesoderm

{ $ eve4 } , visceral mesoderm

{ 0 odd* } , dorsal pouch

, parasegment 6 visceral mesoderm

{ 0 ftz* } , labial segment

, ventral mesothoracic disc | anterior

, epidermis

, embryonic dorsal vessel | anterior

, visceral mesoderm

{ - eve3 } " DRSC26749 K -0.777456338 -1.504383972 FBgn0013437 copia\GIP gag-int-pol http://flybase.org/reports/FBgn0013437 - transposable_element_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from direct assay" DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 proteolysis ; GO:0006508 | inferred from direct assay - "copia, copia\GIP, copiaGIP" "IPR013103:Reverse transcriptase, RNA-dependent DNA polymerase, IPR001584:Integrase, catalytic core, IPR025724:GAG-pre-integrase domain, IPR012337:Ribonuclease H-like domain, IPR001878:Zinc finger, CCHC-type" - 11-Aug-17 DroID_v2017_08 - - - - - - " adult stage | female , larval stage | second instar , embryonic stage , embryonic stage | stage 13 , embryonic stage | extended germ band , adult stage , larval stage | third instar , embryonic stage | stage >=14 , embryonic stage | stage >=13 " " adult fat body

, ventral neurogenic region

, ventral midline | segmentally repeated

, ventral nerve cord

, embryonic central nervous system

, embryonic brain

" FBgn0005631 robo1 roundabout 1 http://flybase.org/reports/FBgn0005631 FBgn0045796 protein_coding_gene heparin binding ; GO:0008201 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8T4F7 protein binding ; GO:0005515 | inferred from physical interaction with sli receptor activity ; GO:0004872 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Lrt "axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from genetic interaction with Sema1a regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with Sos axon guidance ; GO:0007411 | traceable author statement neuron recognition ; GO:0008038 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | traceable author statement outflow tract morphogenesis ; GO:0003151 | inferred from genetic interaction with robo2 Roundabout signaling pathway ; GO:0035385 | inferred from genetic interaction with sli muscle cell cellular homeostasis ; GO:0046716 | inferred from genetic interaction with Dg inferred from genetic interaction with Dys motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype entrainment of circadian clock ; GO:0009649 | inferred from direct assay locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | traceable author statement embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype dendrite guidance ; GO:0070983 | inferred from mutant phenotype regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype salivary gland boundary specification ; GO:0007432 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay vesicle ; GO:0031982 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay dendrite ; GO:0030425 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay axonal growth cone ; GO:0044295 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Lrt integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with EMBL:AF040990 Slit-Robo signaling complex ; GO:0071666 | inferred from direct assay "robo, robo1, CG13521, Robo-1, Robo, CT32892, Robo1, dRobo, dRobo1, D-Robo1, BEST:GM07780, ROBO, robo1S, roundabout" "IPR003598:Immunoglobulin subtype 2, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain, IPR003599:Immunoglobulin subtype, IPR013098:Immunoglobulin I-set" CG13521 11-Aug-17 DroID_v2017_08 "Drer\prtga, Drer\cntn3a.2, Drer\igdcc3, Drer\ncam1a, Drer\si:ch211-57n23.4, Drer\pvrl1b, Drer\LOC101883325, Drer\ncam1b, Drer\pvrl2l, Drer\boc, Drer\cntn3a.1, Drer\pvrl3b, Drer\xcr1b.3, Drer\cdon, Drer\robo3, Drer\hepacam2, Drer\robo2, Drer\pvrl1a, Drer\cadm1a, Drer\cntn5, Drer\si:ch211-119e14.9, Drer\si:ch73-22o12.1, Drer\cntn3b, Drer\mxra5b, Drer\pvrl3a, Drer\si:dkey-281i8.1, Drer\robo1, Drer\cntn4, Drer\mxra5a, Drer\prtgb, Drer\hmcn2, Drer\si:ch211-222f23.6, Drer\ncam2, Drer\cadm2b, Drer\robo4, Drer\zgc:152904" - "Cele\rig-4, Cele\sax-3" "Xtro\cadm2, Xtro\robo4, Xtro\robo3, Xtro\pvrl3, Xtro\robo1, Xtro\robo2, Xtro\pvrl2, Xtro\siglec10, Xtro\igsf9b, Xtro\pvrl1" "Mmus\Igsf9b, Mmus\Cdon, Mmus\Ncam2, Mmus\Pvr, Mmus\Boc, Mmus\Nectin1, Mmus\Igdcc4, Mmus\Iglon5, Mmus\Robo3, Mmus\Cntn4, Mmus\Nectin3, Mmus\Igdcc3, Mmus\Nectin2, Mmus\Robo2, Mmus\Prtg, Mmus\Cntn3, Mmus\Nectin4, Mmus\Cntn5, Mmus\Robo4, Mmus\Opcml, Mmus\Ncam1, Mmus\Robo1, Mmus\Cntn6" "Hsap\NCAM2, Hsap\CADM2, Hsap\IGDCC3, Hsap\ROBO2, Hsap\HEPACAM2, Hsap\OPCML, Hsap\PRTG, Hsap\CNTN3, Hsap\CNTN5, Hsap\NECTIN1, Hsap\NECTIN4, Hsap\IGDCC4, Hsap\PVR, Hsap\IGSF9B, Hsap\NECTIN2, Hsap\ROBO4, Hsap\CNTN6, Hsap\ROBO1, Hsap\CNTN4, Hsap\ROBO3, Hsap\IGLON5, Hsap\NECTIN3, Hsap\CDON, Hsap\NCAM1, Hsap\BOC" " embryonic stage | stage 13-15 , embryonic stage | late , embryonic stage | stage 12 , embryonic stage | stage 12-17 , embryonic stage | stage 14 " " longitudinal muscle && muscle attachment site

, longitudinal connective

, MP1 neuron

, vMP2 neuron

, dMP2 neuron

, ventral neurogenic region

, muscle attachment site

, epidermis

, neuron

, sensory neuron | dorsal & subset

, abdominal lateral pentascolopidial chordotonal organ lch5

, pCC neuron

, aCC neuron

" "neuroanatomy defective,male,viable,fertile,stress response defective,circadian rhythm defective,wild-type,lethal,dominant,recessive,somatic clone,neurophysiology defective,female,visible,body color defective,partially lethal - majority die,some die during pupal stage" "tract,ectopic,gustatory receptor neuron,male,prothoracic leg taste bristle chemosensory neuron,macrochaeta,presumptive embryonic/larval central nervous system,longitudinal connective,midline crossing tract,commissure,ganglionic branch primordium,cardioblast,dendrite,class IV dendritic arborizing neuron,dorsal multidendritic neuron ddaC,ventral nerve cord,embryonic/larval neuron,interface glial cell,ventral nerve cord commissure,medial longitudinal fascicle,pCC neuron,thoracic-abdominal embryonic fiber tract,vMP2 tract,fascicle,MP1 neuron,vMP2 neuron,dMP2 neuron,chordotonal organ & axon | lateral,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,A1-7 lateral oblique muscle 1,lch5 neuron,lesA neuron,lateral multidendritic neuron ldaA,posterior fascicle sensory neuron,presumptive embryonic salivary gland,abdominal basiconical sensillum dbd & embryo & nerve terminal,chordotonal organ & embryo & nerve terminal,axon,dorsal abdominal cluster,somatic clone,motor neuron,neuropil,dendrite | somatic clone,gonad,germline cell,embryonic somatic muscle,ventral,RP2 motor neuron,filopodium | embryonic stage,interneuron,axon & pCC neuron,SP1 neuron,anterior commissure,posterior commissure,central nervous system,aCC neuron,presumptive embryonic/larval muscle system,ganglion mother cell GMC1-1a,RP2sib neuron,giant fiber neuron,tergal depressor of trochanter muscle motor neuron & dendriteshakB.lethal.4.1,intersegmental nerve,female,A1-7 lateral transverse muscle 1,A1-7 lateral transverse muscle 2,A1-7 lateral transverse muscle 3,antennal lobe glomerulus,antennal glomerulus DM2 & olfactory neuronlz-gal4,antennal glomerulus DM6 & olfactory neuronlz-gal4,antennal commissure,synapse | adult stage,synapse | adult stageshakB.lethal.4.1,synapse | adult stagec17,dendriteeve.CQ2,midline crossing tract | embryonic stage 16,dendrite | somatic cloneVGlut-OK371,abdominal lateral pentascolopidial chordotonal organ lch5,dorsal branch | third instar larval stage,trichogen cell,mesothoracic tergum" FBgn0003975 vg vestigial http://flybase.org/reports/FBgn0003975 - protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay contributes_to protein C-terminus binding ; GO:0008022 | inferred from physical interaction with UniProtKB:P30052 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P17719" "imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype wing disc proximal/distal pattern formation ; GO:0007473 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | non-traceable author statement haltere development ; GO:0007482 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype determination of muscle attachment site ; GO:0016204 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from direct assay somatic muscle development ; GO:0007525 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from genetic interaction with sd imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from genetic interaction with cpa" nucleus ; GO:0005634 | inferred from direct assay "Vg, CG3830, VG, vg21, vg" "IPR006627:TDU repeat, IPR011520:Vestigial familiy" CG3830 11-Aug-17 DroID_v2017_08 "Drer\vgll3, Drer\si:dkeyp-93d12.1, Drer\vgll2b, Drer\si:ch73-52f15.5" - - "Xtro\vgll3, Xtro\cfap70, Xtro\vgll2, Xtro\vgll1" "Mmus\Vgll2, Mmus\Vgll3, Mmus\Vgll1" "Hsap\VGLL3, Hsap\VGLL1, Hsap\VGLL2" " embryonic stage | stage 12-17 , embryonic stage | stage 14-16 , embryonic stage | stage 10-13 , embryonic stage && pupal stage && adult stage , larval stage , embryonic stage , larval stage | third instar , embryonic stage | stage 11-17 , embryonic stage | stage 13-16 " " embryonic central nervous system | presumptive | segmentally repeated pattern

, abdomen | restricted

, embryonic central nervous system | presumptive | restricted

, dorsal prothoracic disc

, dorsal metathoracic disc

, ectoderm | stripes <&> dorsal

,

{ $ vg* } , dorsal mesothoracic disc

{ & vg* } , ectoderm | stripes <&> lateral

, larval brain

, head | restricted

, dorsal metathoracic disc | restricted

, dorsal mesothoracic disc

" " larval stage | second instar , larval stage | third instar , pupal stage | 21 hr , pupal stage , embryonic stage | stage >12 " " dorsal mesothoracic disc

, mesothoracic tergum primordium | distal

, myoblast | subset & vicinity of dorsal medial muscle

, mesothoracic lateral longitudinal muscle

, myoblast | subset

, dorsal medial muscle

, adepithelial cell of dorsal mesothoracic disc

, myoblast &&of mesothoracic tergum primordium | proximal

" "lethal,recessive,female sterile,visible,female fertile,male fertile,viable,dominant,lethal - all die before end of pupal stage,somatic clone,some die during pupal stage,germline clone,chemical resistant,cold sensitive,increased cell death,chemical sensitive,heat sensitive,male sterile,conditional,flightless,partially lethal - majority live,sterile,poor,reduced,homeotic,lethal - all die before end of embryonic stage,some die during embryonic stage,cytokinesis defective,size defective,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" "wing,haltere,postnotum,adult thorax,leg,adult metathoracic segment,axillary cord,wing disc,somatic clone,A1-7 ventral oblique muscle 4,A1-7 ventral oblique muscle 5,A2-7 ventral oblique muscle 6,embryonic/larval cardial cell,lateral transverse muscle,muscle attachment site,ectopic,distal,cold sensitive,dorsal medial muscle,lateral oblique dorsal muscle,tergosternal muscle,temperature conditional,heat sensitive,eye,coxal tergal remotor muscle,indirect flight muscle,wing blade,A1-7 ventral longitudinal muscle 2,conditional,ventral longitudinal muscle,mesothoracic bristle,scutellum,ovary,scutellar bristle,scutum,sensillum campaniformium of proximal dorsal radius,haltere disc,alula,posterior scutellar bristle,mesothoracic tergum,wing pouch,metathoracic leg,tarsal segment,tergite,wing sensillum,wing vein L2 & wing sensillum,wing vein L3 & wing sensillum,mesothoracic leg,prothoracic leg,proboscis,genitalia,antenna,wing margin bristle,wing vein,wing sensillum & sensillum campaniformium | ectopicDll-md23,wing hair,direct flight muscle,basalar muscle 51,basalar muscle 52,second segment of antenna,third segment of antenna,head,mesothoracic tergum & chaeta | supernumerary-C253,thorax,eye disc,anterior wing margin,posterior wing margin,interommatidial bristle,ommatidium,tibia,femur,metatarsus,unguis,posterior" DRSC07715 I -2.037663603 0.302904998 0.916856653 0.055163459 0.252946681 0.493765859 FBgn0001148 gsb gooseberry http://flybase.org/reports/FBgn0001148 - protein_coding_gene RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001523, InterPro:IPR017970 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype inferred from genetic interaction with gsb-n salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | non-traceable author statement segment polarity determination ; GO:0007367 | inferred from genetic interaction with gsb-n regulation of synaptic activity ; GO:0060025 | inferred from direct assay ventral cord development ; GO:0007419 | traceable author statement chemical synaptic transmission ; GO:0007268 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from mutant phenotype "CG3388, gsb-d, Gsb-d, gsbd, BSH9, l(2)01155, GSB-D, gsb-2, gsb-distal, gsbBSH9, BSH-9, l(2)gsb, BSH9c2, gsb, Gsb" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain" CG3388 11-Aug-17 DroID_v2017_08 "Drer\pax3b, Drer\pax6b, Drer\pax2b, Drer\pax1b, Drer\pax5, Drer\pax7b, Drer\arxb, Drer\pax4, Drer\mixl1, Drer\pax8, Drer\mxtx2, Drer\pax2a, Drer\pax1a, Drer\pax9, Drer\pax10, Drer\pax7a, Drer\pax3a, Drer\mxtx1, Drer\arxa, Drer\pax6a" - "Cele\alr-1, Cele\pax-3, Cele\F31E3.2, Cele\egl-38, Cele\pax-1, Cele\vab-3, Cele\pax-2" "Xtro\pax9, Xtro\pax1, Xtro\pax7, Xtro\pax6, Xtro\bix1.1, Xtro\pax2, Xtro\sia1, Xtro\arx, Xtro\pax3, Xtro\pax5, Xtro\pax8, Xtro\mixer, Xtro\mix1" "Mmus\Duxbl2, Mmus\Duxbl1, Mmus\Pax3, Mmus\Pax2, Mmus\Pax4, Mmus\Pax1, Mmus\Pax9, Mmus\Arx, Mmus\Pax5, Mmus\Cphx3, Mmus\Cphx1, Mmus\Pax8, Mmus\Pax7, Mmus\Mixl1, Mmus\Pax6, Mmus\Duxbl3" "Hsap\PAX9, Hsap\PAX3, Hsap\PAX5, Hsap\PAX4, Hsap\DUX4, Hsap\MIXL1, Hsap\ARX, Hsap\DUXA, Hsap\PAX1, Hsap\PAX6, Hsap\PAX8, Hsap\PAX7, Hsap\PAX2" " embryonic stage | stage 10-14 , embryonic stage | stage 13 , embryonic stage | 4-8 hr , embryonic stage | gastrula--embryonic stage | extended germ band , embryonic stage | >=stage 5 , embryonic stage | stage 10-12 , embryonic stage | embryonic cycle 14A , embryonic stage | stage 17 , embryonic stage | stage 5-13 " " ectoderm

, ventral nerve cord | anterior

, organism | striped

, abdominal segment 1--11 , thoracic segment | posterior

segmentally repeated , mesoderm

,

75% egg length , anal pad

, embryonic/larval pharynx | restricted

, organism | anterior

, organism | 70% egg length

, head segment

segmentally repeated " " embryonic stage , embryonic stage | stage 14 , embryonic stage | stage 9-11 , larval stage | third instar , embryonic stage | stage 8-11 , embryonic stage | stage 10 , embryonic stage | stage 9-13 , embryonic stage | stage 4-13 , embryonic stage | stage 10-12 , embryonic stage | stage 8-13 , embryonic stage | stage 10-13 , embryonic stage | stage 11 " " neuroblast | row 5

, embryonic/larval pharynx | restricted

, deuterocerebral neuroblast | subset

, neuroblast | row 6/7

, ectoderm && embryonic labral segment | restricted

, female genital disc | restricted

, ventral neurogenic region && embryonic ocular segment | restricted

, ventral neurogenic region | segmentally repeated

, protocerebral neuroblast | subset

, abdominal segment 9--11

, male genital disc | restricted

, intercalary segment | restricted

,

segmentally repeated , neuroblast

, embryonic intercalary segment

, anal pad | restricted

, labral segment | restricted

, ventral neurogenic region && embryonic antennal segment | restricted & anterior

, tritocerebral neuroblast | subset

, mesoderm

" "lethal - all die before end of embryonic stage,recessive,lethal,some die during embryonic stage,wild-type,pair rule phenotype,heat sensitive,visible,viable" "wing,denticle belt,cuticle,RP2 motor neuron,U neuron,U1 neuron,U2 neuron,U3 neuron,posterior commissure,embryonic segment,posterior compartment,ectopic,epidermis,neuroblast NB4-2,presumptive embryonic salivary gland,abdominal 4 ventral denticle belt,EL neuron,abdominal 1 ventral denticle belt,heat sensitive,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,neuroblast MP2,embryonic epidermis,Keilin's organ,embryonic central nervous system & neuroblast | conditional ts,aCC neuron,pCC neuron,RP2sib neuron,neuroblast NB6-4,neuroblast NB7-3,embryonic head,embryonic dorsal epidermis,embryonic central nervous system & neuroblast,eye,adult head,antenna" FBgn0002569 Mal-A2 Maltase A2 http://flybase.org/reports/FBgn0002569 - protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "D, CG8694, Mal-A2, mal_A2, LvpD, lvpD, Drome_A2" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG8694 11-Aug-17 DroID_v2017_08 "Drer\zgc:158423, Drer\slc3a2b, Drer\slc3a1, Drer\slc3a2a, Drer\si:dkey-202g17.3" "Scer\IMA4, Scer\IMA3, Scer\IMA2, Scer\IMA1, Scer\MAL32, Scer\IMA5, Scer\MAL12" "Cele\atgp-1, Cele\atgp-2" "Xtro\slc3a2, Xtro\slc3a1" "Mmus\Slc3a1, Mmus\Slc3a2" "Hsap\SLC3A1, Hsap\SLC3A2" " larval stage | second instar , adult stage , larval stage | first instar , larval stage | early third instar larval stage " organism

viable FBgn0027950 MBD-like Methyl-CpG binding domain protein-like http://flybase.org/reports/FBgn0027950 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from physical interaction with HDAC1 methyl-CpG binding ; GO:0008327 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with MBD-like protein binding ; GO:0005515 | inferred from physical interaction with Caf1-55 methyl-CpG binding ; GO:0008327 | NOT traceable author statement methyl-CpG binding ; GO:0008327 | NOT inferred from direct assay transcription corepressor activity ; GO:0003714 | inferred from direct assay methyl-CpG binding ; GO:0008327 | inferred from biological aspect of ancestor with PANTHER:PTN000273735 "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay methylation-dependent chromatin silencing ; GO:0006346 | inferred from biological aspect of ancestor with PANTHER:PTN000273735 multicellular organism development ; GO:0007275 | traceable author statement chromosome condensation ; GO:0030261 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000273735" polytene chromosome ; GO:0005700 | inferred from direct assay NuRD complex ; GO:0016581 | inferred from physical interaction with HDAC1 inferred from physical interaction with Mi-2 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000273735 NuRD complex ; GO:0016581 | inferred from physical interaction with Mi-2 nucleus ; GO:0005634 | inferred from physical interaction with HDAC1 inferred from physical interaction with Mi-2 "MBD2/3, dMbD2/3, CG8208, Dm Mbd2/3, DmMbd2/3, dMBD2/3, dMBD-like, MBD2-3, MBD-like, MBD2, MBD3" "IPR025884:Methyl-CpG binding protein 2/3, C-terminal domain, IPR001739:Methyl-CpG DNA binding, IPR016177:DNA-binding domain, IPR032343:Methyl-CpG-binding domain protein 2/3, p55-binding region" CG8208 11-Aug-17 DroID_v2017_08 "Drer\mbd2, Drer\mbd1b, Drer\mbd3a, Drer\mbd3b" - Cele\mbd-2 "Xtro\mbd3, Xtro\mbd2" "Mmus\Mbd3l2, Mmus\Mbd2, Mmus\Mbd3l1, Mmus\Mbd1, Mmus\Mbd3" "Hsap\MBD3L5, Hsap\MBD3L4, Hsap\LOC729458, Hsap\MBD3, Hsap\MBD3L2, Hsap\MBD2, Hsap\MBD3L1, Hsap\MBD3L3" adult stage " testis

, ovary

" " adult stage , embryonic stage | cellular blastoderm , embryonic stage | 6-20 hr , embryonic stage | 0-12 hr , embryonic stage | stage < 4 " " spermatogonium

, primary gonial cell

, spermatocyte

, organism

" "viable,fertile,small body,suppressor of variegation,dominant" "heart primordium,mitotic anaphase & nuclear chromosome" FBgn0026196 nop5 nop5 http://flybase.org/reports/FBgn0026196 FBgn0022271 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000096022 rRNA processing ; GO:0006364 | inferred from sequence or structural similarity with SGD:S000005837 cellular response to starvation ; GO:0009267 | inferred from expression pattern rRNA modification ; GO:0000154 | inferred from biological aspect of ancestor with PANTHER:PTN000096022 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000096022 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with SGD:S000005837 inferred from direct assay box C/D snoRNP complex ; GO:0031428 | inferred from biological aspect of ancestor with PANTHER:PTN000096022 "FBgn0026196, Dnop5, 2/30, CG10206, nop5, Nop5, DNOP5, NOP5" "IPR002687:Nop domain, IPR012974:NOP5, N-terminal, IPR012976:NOSIC" CG10206 11-Aug-17 DroID_v2017_08 "Drer\nop58, Drer\nop56" Scer\NOP58 Cele\nol-5 "Xtro\nop58, Xtro\nop56" "Mmus\Nop56, Mmus\Nop58" "Hsap\NOP56, Hsap\NOP58" " embryonic stage | stage 13 , larval stage | third instar , embryonic stage | stage 11 , embryonic stage | stage 12 , embryonic stage | stage 6 , embryonic stage | stage 8 , adult stage | female " " midgut

, dorsal mesothoracic disc | restricted & posterior

, mesoderm

, embryonic brain

, eye-antennal disc

, ventral thoracic disc

, ovary

" embryonic stage | stage 4-16 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027363 Stam Signal transducing adaptor molecule http://flybase.org/reports/FBgn0027363 - protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000000994 "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002014 positive regulation of fibroblast growth factor receptor signaling pathway ; GO:0045743 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | traceable author statement regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000000994 endosomal transport ; GO:0016197 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle endocytosis ; GO:0048488 | non-traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from genetic interaction with Hrs regulation of cell cycle ; GO:0051726 | inferred from genetic interaction with Hrs" ESCRT-0 complex ; GO:0033565 | inferred from sequence or structural similarity with SGD:S000000994 "stam, STAM, Dstam, CG6521, Stam, dstam, Stam1" "IPR001452:SH3 domain, IPR002014:VHS domain, IPR003903:Ubiquitin interacting motif, IPR008942:ENTH/VHS" CG6521 11-Aug-17 DroID_v2017_08 "Drer\grb2b, Drer\grb2a, Drer\stam, Drer\stam2, Drer\sh3gl2, Drer\sh3gl1b, Drer\sh3gl3b" "Scer\HSE1, Scer\PIN3, Scer\GGA2" "Cele\stam-1, Cele\sem-5, Cele\unc-57" "Xtro\stam2, Xtro\sh3gl1, Xtro\stam, Xtro\grb2" "Mmus\Grb2, Mmus\Sh3gl1, Mmus\Sh3gl3, Mmus\Stam2, Mmus\Stam, Mmus\Sh3gl2" "Hsap\SH3GL3, Hsap\SH3GL2, Hsap\STAM, Hsap\SH3GL1, Hsap\GRB2, Hsap\STAM2" " embryonic stage | stage >=14 , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage | syncytial blastoderm , embryonic stage | stage 11-13 , adult stage && oogenesis stage | stage >=S9 , embryonic stage | stage >=7 , adult stage && oogenesis stage | stage S9-10 " " ventral nerve cord | restricted

, oocyte

, ventral nerve cord | segmentally repeated

,

segmentally repeated , nurse cell

" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,lethal,recessive" "major mitochondrial derivativenos.PG, nos.UTR.THsimVP16, otu.THsimVP16,trichogen cell,dorsal air sac primordium,somatic clone,eye,photoreceptor cell,imaginal disc epithelial cell" FBgn0001185 her hermaphrodite http://flybase.org/reports/FBgn0001185 FBgn0005174 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 DNA binding ; GO:0003677 | traceable author statement "neurogenesis ; GO:0022008 | inferred from mutant phenotype sex differentiation ; GO:0007548 | traceable author statement sex determination ; GO:0007530 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement female somatic sex determination ; GO:0019101 | non-traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement" - "l(2)mat, CG4694, her, FBgn 1185" IPR013087:Zinc finger C2H2-type CG4694 11-Aug-17 DroID_v2017_08 Drer\znf513 - - - "Mmus\Zfp513, Mmus\Rest" "Hsap\ZNF513, Hsap\REST" embryonic stage -- adult stage "viable,fertile,lethal,female,maternal effect,heat sensitive,sex-determination defective,recessive,wild-type,partially lethal - majority die,male,female semi-sterile,male fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,neuroanatomy defective" "sex comb,maternal effect,female terminalia,male terminalia,male abdominal 5 muscle,epiproct,abdominal sternite 6,embryonic/larval neuroblast,ganglion mother cell" FBgn0026415 Idgf4 Imaginal disc growth factor 4 http://flybase.org/reports/FBgn0026415 FBgn0026066 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 imaginal disc growth factor receptor binding ; GO:0008084 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 imaginal disc development ; GO:0007444 | inferred from direct assay wound healing ; GO:0042060 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "IDGF, CG1780, IDGF4, IDGF-4, Idgf4, idgf4, DmIDGF4" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG1780 11-Aug-17 DroID_v2017_08 "Drer\chia.3, Drer\ovgp1, Drer\si:ch211-226m16.2, Drer\chia.4, Drer\chia.6, Drer\chia.2, Drer\chia.5" Scer\CTS2 "Cele\chil-25, Cele\chil-20, Cele\chil-15, Cele\chil-12, Cele\chil-24, Cele\chil-18, Cele\T19H5.6, Cele\lmd-5, Cele\chil-4, Cele\chil-8, Cele\chil-17, Cele\chil-16, Cele\chil-5, Cele\chil-6, Cele\chil-7, Cele\chil-2, Cele\chil-22, Cele\chil-19, Cele\chil-11, Cele\chil-3, Cele\lmd-4, Cele\chil-23, Cele\cht-2, Cele\chil-13" "Xtro\chit1, Xtro\chia, Xtro\ctbs, Xtro\LOC548945" "Mmus\Chil3, Mmus\Chil6, Mmus\Chil5, Mmus\Chil1, Mmus\Chia1, Mmus\Chit1, Mmus\Ctbs, Mmus\Ovgp1, Mmus\Chil4" "Hsap\CHI3L2, Hsap\CHI3L1, Hsap\CHIA, Hsap\CHIT1, Hsap\OVGP1" " embryonic stage && larval stage , embryonic stage , larval stage | third instar , adult stage && oogenesis stage " " embryonic/larval fat body

, ventral furrow | vicinity of

, cephalic furrow | vicinity of

, embryonic/larval salivary gland

, larval brain

, larval optic lobe

, ring gland

, oocyte

, embryonic/larval tracheal system

, amnioproctodeal invagination | vicinity of

, yolk

, nurse cell

, imaginal disc

, lymph gland

" "viable,fertile" FBgn0021776 mira miranda http://flybase.org/reports/FBgn0021776 - protein_coding_gene myosin binding ; GO:0017022 | inferred from physical interaction with jar protein binding ; GO:0005515 | inferred from physical interaction with flfl actin binding ; GO:0003779 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with stau "neuroblast fate determination ; GO:0007400 | traceable author statement neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from genetic interaction with cup ventral cord development ; GO:0007419 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | traceable author statement protein localization to cell cortex ; GO:0072697 | inferred from genetic interaction with fray, Lkb1 anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype ganglion mother cell fate determination ; GO:0007402 | traceable author statement intracellular mRNA localization ; GO:0008298 | non-traceable author statement asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype inferred from genetic interaction with pros inferred from physical interaction with pros asymmetric neuroblast division ; GO:0055059 | traceable author statement" basal cortex ; GO:0045180 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay basal cortex ; GO:0045180 | traceable author statement apical part of cell ; GO:0045177 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay apical part of cell ; GO:0045177 | traceable author statement basal part of cell ; GO:0045178 | inferred from direct assay basal plasma membrane ; GO:0009925 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay aster ; GO:0005818 | colocalizes_with inferred from direct assay basal cortex ; GO:0045180 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement "Mira, Mir, mir, MIR, CG12249, mira, MIRA, Miranda" - CG12249 11-Aug-17 DroID_v2017_08 - - - - - Hsap\SLMAP " embryonic stage | stage >=8 , embryonic stage | stage 3 , embryonic stage | stage >=12 " " neuroblast

, ventral nerve cord | ventral

, sensory mother cell

, posterior midgut proper primordium

, embryonic brain

" " embryonic stage | stage >=8 , embryonic stage | cycle 1-9 , embryonic stage | stage >=12 , larval stage | third instar , embryonic stage , embryonic stage -- adult stage , embryonic stage | early , embryonic stage | cycle 10-11 " " sensory mother cell

, midgut primordium

, posterior midgut proper primordium

, organism

, neuroblast

, embryonic brain

, ventral nerve cord && neuroblast

, neuroblast

, ventral nerve cord | ventral

, ventral nerve cord && ganglion mother cell

, organism

, peripheral nervous system

" "neuroanatomy defective,lethal,recessive,tumorigenic,visible,homeotic,fertile" "glial cell,supernumerary,embryonic ganglion mother cell,commissure,neuroblast NB6-4 of thorax,embryonic/larval glial cell,neuroblast NB6-4,longitudinal connective,embryonic/larval neuron,ventral neurectoderm,embryonic neuroblast,embryonic/larval cell body glial cell,embryonic abdomen,ectopic,embryonic head,embryonic thorax,pole cell" FBgn0003483 spn-E spindle E http://flybase.org/reports/FBgn0003483 FBgn0004883 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 RNA-dependent ATPase activity ; GO:0008186 | traceable author statement RNA helicase activity ; GO:0003724 | traceable author statement "oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype RNA localization ; GO:0006403 | traceable author statement chromatin silencing ; GO:0006342 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement intracellular mRNA localization ; GO:0008298 | traceable author statement germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with mus301 oocyte maturation ; GO:0001556 | inferred from mutant phenotype polarity specification of dorsal/ventral axis ; GO:0009951 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from genetic interaction with fs(1)K10 oogenesis ; GO:0048477 | inferred from mutant phenotype positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype RNA interference ; GO:0016246 | traceable author statement targeting of mRNA for destruction involved in RNA interference ; GO:0030423 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | non-traceable author statement pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype polarity specification of anterior/posterior axis ; GO:0009949 | inferred from mutant phenotype RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 karyosome formation ; GO:0030717 | inferred from mutant phenotype negative regulation of transposition, DNA-mediated ; GO:0000335 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000433398 cytoplasm ; GO:0005737 | non-traceable author statement P granule ; GO:0043186 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "homeless, hls, Spn-E, spn-E/hls, spnE, spn E, fs(1)hls, fs(3)hls, CG3158, spn-E, SPN-E, hes, spin-E, SpnE" "IPR001650:Helicase, C-terminal, IPR002999:Tudor domain, IPR007502:Helicase-associated domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR013087:Zinc finger C2H2-type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011545:DEAD/DEAH box helicase domain" CG3158 11-Aug-17 DroID_v2017_08 "Drer\dhx36, Drer\dhx9, Drer\tdrd9, Drer\dhx30, Drer\dhx29, Drer\dhx57" Scer\YLR419W - "Xtro\ythdc2, Xtro\dhx29, Xtro\dhx30, Xtro\tdrd9, Xtro\dhx9, Xtro\dhx36" "Mmus\Dhx57, Mmus\Tdrd9, Mmus\Dhx30, Mmus\Dhx36, Mmus\Ythdc2, Mmus\Dhx9, Mmus\Dhx29" "Hsap\DHX29, Hsap\DHX9, Hsap\TDRD9, Hsap\DHX30, Hsap\DHX57, Hsap\YTHDC2, Hsap\DHX36" " adult stage && oogenesis stage , oogenesis stage && adult stage | female , embryonic stage | early " " nurse cell

, germarium

, female germline stem cell

, ovary

,

ubiquitous " "suppressor of variegation,female sterile,female sterile germline-dependent,meiotic cell cycle defective,recessive,sterile,male fertile,male sterile,fertile,partially,lethal,polyphasic,lethal - all die before end of embryonic stage,some die during embryonic stage,non-suppressor of variegation,dominant,viable" "meiosis & nuclear chromosome,P granule,oocyte,egg chamber,dorsal appendage,microtubule,germline clone,karyosome,synaptonemal complex,germline cyst,egg,dorsal,meiosis & nuclear chromosome | male,spermatocyte" DRSC17064 K -0.598062282 0.232337059 -0.238993792 -0.329629295 -0.36659883 -1.610703376 FBgn0016984 sktl skittles http://flybase.org/reports/FBgn0016984 "FBgn0010601, FBgn0015387" protein_coding_gene 1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308 | non-traceable author statement 1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308 | traceable author statement 1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q94545 phosphatidylinositol metabolic process ; GO:0046488 | inferred from electronic annotation with InterPro:IPR002498 cellular protein localization ; GO:0034613 | inferred from mutant phenotype basement membrane organization ; GO:0071711 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern phosphorylation ; GO:0016310 | non-traceable author statement negative regulation of histone phosphorylation ; GO:0033128 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification ; GO:0042070 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity polytene chromosome ; GO:0005700 | inferred from genetic interaction with UniProtKB:Q94545 apical plasma membrane ; GO:0016324 | colocalizes_with inferred from direct assay exocyst ; GO:0000145 | colocalizes_with inferred from mutant phenotype cell cortex ; GO:0005938 | inferred from direct assay male germline ring canal ; GO:0035323 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "PIP5K 57B6, CG9985, l(2)k12405, l(2)05475, 25/17, ski, fam, sktl, PIP5K, Sktl, PIP5-kinase" "IPR002498:Phosphatidylinositol-4-phosphate 5-kinase, core, IPR023610:Phosphatidylinositol-4-phosphate 5-kinase, IPR027484:Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain, IPR027483:Phosphatidylinositol-4-phosphate 5-kinase, C-terminal" CG9985 11-Aug-17 DroID_v2017_08 "Drer\pip5k1ca, Drer\pip5kl1, Drer\si:ch211-243a15.1, Drer\pip5k1bb, Drer\pip5k1ba, Drer\pip4k2ab, Drer\pip4k2cb, Drer\psmd4a, Drer\pip4k2aa, Drer\pip5k1aa, Drer\pip5k1ab, Drer\pip4k2ca" Scer\MSS4 Cele\ppk-1 "Xtro\psmd4, Xtro\pip4k2c, Xtro\pip5kl1, Xtro\pip5k1b, Xtro\pip5k1a, Xtro\pip4k2a, Xtro\pip5k1c" "Mmus\Psmd4, Mmus\Pip4k2a, Mmus\Pip5kl1, Mmus\Pip4k2c, Mmus\Pip5k1a, Mmus\Pip5k1b, Mmus\Pip4k2b, Mmus\Pip5k1c" "Hsap\PIP5K1B, Hsap\PIP5K1A, Hsap\PIP4K2C, Hsap\PIP5KL1, Hsap\PSMD4, Hsap\PIP4K2B, Hsap\PIP5K1C, Hsap\PIP4K2A" " embryonic stage | stage 11-13 , embryonic stage | stage 5 , embryonic stage | stage 17 , spermatogenesis , embryonic stage | gastrula , larval stage | third instar , embryonic stage | stage 4-5 , embryonic stage | stage 13 , adult stage | female , oogenesis stage , embryonic stage | 0-24 hr , embryonic stage , embryonic stage | stage 12-13 , embryonic stage | stage 11 " " embryonic central nervous system | precursor

, procephalic neurogenic region

, embryonic central nervous system | restricted

, spermatocyte

, ventral furrow

, photoreceptor cell R8 | precursor

, embryonic/larval midgut

, mesoderm

, embryonic/larval hindgut

, morphogenetic furrow | anterior to

, nurse cell

,

ubiquitous , embryonic peripheral nervous system | precursor

, ectoderm

, embryonic/larval foregut | restricted

, oocyte

, embryonic/larval pharynx

, cephalic furrow

, embryonic/larval dorsal vessel

, embryonic/larval hindgut | restricted

, embryonic nervous system

, germarium | restricted

, embryonic/larval foregut

, imaginal disc

, embryonic/larval midgut | restricted

, larval brain

, pole cell

" "cytokinesis defective,germline clone,female sterile,lethal,cell shape defective,somatic clone,cell polarity defective,recessive,some die during immature adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,visible,lethal - all die before end of pupal stage,some die during pupal stage" "oocyte nucleus,germline clone,dorsal appendage,maternal effect,actin filament & oocyte | germ-line clone,yolk granule | germline clone,spermatid cyst,egg,follicle cell,somatic clone,endocytic vesiclenos.PG,yolk granulenos.PG,rhabdomereGMR.PF,presumptive embryonic/larval peripheral nervous system,chordotonal organ,lateral,imaginal disc,wing,wing & macrochaeta,ovary,nurse cell & nucleus,wing & macrochaetadpp.blk1,scutum & macrochaetadpp.blk1,macrochaeta,ectopic,scutum,wing & macrochaeta32B,scutum & macrochaeta32B" FBgn0003165 pum pumilio http://flybase.org/reports/FBgn0003165 "FBgn0004871, FBgn0010759, FBgn0014132, FBgn0015529, FBgn0046414" protein_coding_gene "mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay RNA binding ; GO:0003723 | inferred from physical interaction with Ace inferred from physical interaction with dlg1 mRNA 3'-UTR binding ; GO:0003730 | traceable author statement translation repressor activity, nucleic acid binding ; GO:0000900 | traceable author statement" "negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement mitotic nuclear division ; GO:0007067 | traceable author statement regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from direct assay long-term memory ; GO:0007616 | traceable author statement pole cell migration ; GO:0007280 | inferred from mutant phenotype negative regulation of cell cycle ; GO:0045786 | traceable author statement negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | traceable author statement cell migration ; GO:0016477 | traceable author statement pole cell migration ; GO:0007280 | traceable author statement negative regulation of translation ; GO:0017148 | traceable author statement nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | traceable author statement long-term memory ; GO:0007616 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from direct assay chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype germ cell development ; GO:0007281 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype modulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement oogenesis ; GO:0048477 | traceable author statement posttranscriptional gene silencing ; GO:0016441 | inferred from direct assay head involution ; GO:0008258 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | non-traceable author statement" type Ib terminal bouton ; GO:0061176 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay muscle cell postsynaptic density ; GO:0097482 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay type Is terminal bouton ; GO:0061177 | inferred from direct assay "pum, CG9763, ovt, EP(3)0883, CG9755, l(3)01688, pkl, bem, ova, fs(3)02003, anon-WO0172774.19, Pum, PUM, PKL" "IPR001313:Pumilio RNA-binding repeat, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR011990:Tetratricopeptide-like helical domain, IPR020683:Ankyrin repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR033133:Pumilio homology domain, IPR033712:Pumilio, RNA binding domain" CG9755 11-Aug-17 DroID_v2017_08 "Drer\pum1, Drer\pum2" "Scer\PUF3, Scer\MPT5, Scer\PUF4, Scer\PUF2" "Cele\fbf-1, Cele\fbf-2, Cele\puf-8, Cele\puf-6, Cele\puf-7, Cele\puf-5, Cele\puf-11, Cele\puf-9, Cele\puf-3" "Xtro\pum1, Xtro\pum2" "Mmus\Pum2, Mmus\Pum1" "Hsap\PUM1, Hsap\PUM2" " embryonic stage | early , oogenesis stage && adult stage | female , embryonic stage , adult stage && oogenesis stage , adult stage && oogenesis stage | stage >=S9 " " organism | 0-10% egg length

, ovary

,

ubiquitous , germarium

, border follicle cell

, pole cell

" " adult stage , adult stage && oogenesis stage " " central nervous system

, mushroom body

, female germline stem cell &&of germarium region 1

, cystoblast &&of germarium region 1

" "visible,recessive,lethal,memory defective,chemical sensitive,learning defective,viable,fertile,female sterile,neurophysiology defective,sterile,locomotor behavior defective,semidominant,reduced,uncoordinated,flight defective,partially lethal - majority die,neuroanatomy defective,short lived,wild-type,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,maternal effect,somatic clone,heat sensitive" "macrochaeta,ovary,female germline stem cell,ovariole,nurse cell,oocyte,nurse cell ring canal,interfollicle cell,terminal filament,germline clone,spectrosome,neuromuscular junction,aCC neuron,RP2 motor neuron,wing vein,ectopic,metathoracic tergum,motor neuron,anterior fascicle & synapse,intersegmental nerve,Bolwig nerve,wing,eye,embryonic abdominal segment,embryonic head,maternal effect,embryo,posterior,germarium,mouth hooks,dendritic arborising neuron & dendrite | somatic clone,germline cell,somatic clone,pole cell,embryonic epidermis,embryonic abdomen,larval head,cephalopharyngeal skeleton,dorsal closure embryo,embryonic/larval neuromuscular junction,NMJ bouton,type I bouton,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11,germ cell & germarium,egg chamber,germline cyst,gonad,dendritic arborising neuron & dendritic tree477,Kenyon cell,adult mushroom body,dendritic arborising neuron & dendritic tree5-78,antennal lobe neuroblast,wing margin" DRSC17038 I -1.841870045 0.111860137 -0.985658745 0.100696606 -0.645727979 -0.851432167 FBgn0261270 SelD "Selenide,water dikinase" http://flybase.org/reports/FBgn0261270 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR004536 selenide, water dikinase activity ; GO:0004756 | NOT traceable author statement selenide, water dikinase activity ; GO:0004756 | NOT inferred from direct assay" negative regulation of reactive oxygen species metabolic process ; GO:2000378 | inferred from mutant phenotype selenocysteine biosynthetic process ; GO:0016260 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype selenocysteine biosynthetic process ; GO:0016260 | traceable author statement glutamine metabolic process ; GO:0006541 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype - "selD, CG8553, 142926_at, SPS1, Dm SelD, ptuf1, ptuf, Dm-SelD, SeS, ptf1, l(2)k12303, anon-WO0172774.146, anon-WO0172774.145, SelD, selD/sps1, l(2)SH1599, l(2)SH2 1599, dSPS1, dsps1" "IPR004536:Selenophosphate synthetase, IPR010918:AIR synthase-related protein, C-terminal domain, IPR016188:PurM-like, N-terminal domain" CG8553 11-Aug-17 DroID_v2017_08 "Drer\sps2, Drer\sephs1" - Cele\seld-1 Xtro\sephs1 "Mmus\Sephs1, Mmus\Sephs2" "Hsap\SEPHS2, Hsap\SEPHS1" " embryonic stage | stage >=14 , larval stage | third instar , pupal stage , embryonic stage | stage >=6 , embryonic stage , embryonic stage | stage >=13 , embryonic stage -- adult stage " " gastric caecum | primordium

, larval optic lobe

, adult brain

, ventral nerve cord

, imaginal disc

, midgut primordium

,

ubiquitous , mesoderm

, larval midgut

, larval brain

, embryonic central nervous system

" DRSC07549 IE -1.475439323 -1.963513335 -1.581539245 -0.653011735 -0.073868281 -0.055689444 FBgn0000251 cad caudal http://flybase.org/reports/FBgn0000251 FBgn0082204 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | traceable author statement positive regulation of cell proliferation ; GO:0008284 | inferred from direct assay anterior/posterior axis specification ; GO:0009948 | traceable author statement genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern analia development ; GO:0007487 | traceable author statement genital disc development ; GO:0035215 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype gastrulation involving germ band extension ; GO:0010004 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | traceable author statement cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN001216652 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype germ-band extension ; GO:0007377 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype positive regulation of antimicrobial peptide biosynthetic process ; GO:0002807 | inferred from direct assay animal organ morphogenesis ; GO:0009887 | inferred from biological aspect of ancestor with PANTHER:PTN001216652" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "cd, cad, 38E.19, Cad, S67, anon-WO2004063362.83, CG1759, CAD" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG1759 11-Aug-17 DroID_v2017_08 "Drer\cdx4, Drer\cdx1a, Drer\cdx1b" - "Cele\alr-1, Cele\php-3, Cele\nob-1, Cele\pal-1" "Xtro\cdx4, Xtro\cdx1, Xtro\cdx2" "Mmus\Cdx4, Mmus\Cdx2, Mmus\Cdx1" "Hsap\CDX1, Hsap\CDX2, Hsap\CDX4" " embryonic stage | 13 , adult stage && oogenesis stage , larval stage | third instar , embryonic stage | extended germ band , adult stage && oogenesis stage | stage S11-14 , embryonic stage | embryonic cycle 13 , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | 16-18 hr , adult stage && oogenesis stage | stage S6-11 , adult stage | female , embryonic stage | stage 13 , embryonic stage | early , embryonic stage | syncytial blastoderm , egg stage | unfertilized egg , larval stage , embryonic stage | stage 17 , embryonic stage | embryonic cycle 13-14 , prepupal stage , embryonic stage | >=2-4 hr " "

ubiquitous , inclusive hindgut primordium

, egg chamber

, Malpighian tubule

, amnioproctodeal invagination

, posterior midgut proper primordium

, oocyte

,

anterior posterior gradient ,

posterior , organism | 10-20% egg length

, gonad

, embryonic/larval midgut

, nurse cell

, embryonic midgut | anterior posterior gradient

, organism | 10-60% egg length

, anal pad

, proctodeum

, genital disc | posterior

,

10-60% egg length , unfertilized egg

, embryonic/larval hindgut

, organism

" " embryonic stage | stage 14 , embryonic stage | stage 13 , embryonic stage | stage 4 , embryonic stage | embryonic cycle 8-14 , embryonic stage | gastrula , larval stage | third instar , embryonic stage | embryonic cycle 9 , embryonic stage | embryonic cycle 14A , embryonic stage | embryonic cycle 12-14 , embryonic stage | extended germ band , oogenesis stage , embryonic stage | stage 11 , embryonic stage | embryonic cycle 14B , embryonic stage | late , embryonic stage | embryonic cycle 10-13 " " posterior embryonic midgut

, epidermis | posterior

,

0-50% egg length ,

anterior posterior gradient , pole cell

, male genital disc | restricted

, Malpighian tubule

,

0-55% egg length , posterior midgut proper primordium

, unfertilized egg

30-50% egg length , amnioproctodeal invagination

,

0-30% egg length ,

14-15% egg length , posterior embryonic/larval midgut

, inclusive hindgut primordium

, female genital disc | restricted

, germ band | posterior

, organism | 10-20% egg length

,

0-20% egg length ,

posterior , embryonic anal pad

, anal pad

" "viable,lethal,recessive,visible,somatic clone,melanotic mass phenotype,increased cell number,short lived,germline clone,maternal effect" "abdominal segment 8,abdominal segment 10,abdominal segment 11,abdominal segment 9,abdominal 11 anal tuft,anal pad,embryonic/larval hindgut,Malpighian tubule,embryonic abdominal segment 8,genital disc primordium,male analia,somatic clone,female analia,germline clone,embryonic head,melanotic mass,adult posterior midgut epithelium,head capsule,analia,ectopic,anal plate,adult hindgut,embryonic segment,maternal effect,embryonic abdominal segment" FBgn0011300 babo baboon http://flybase.org/reports/FBgn0011300 "FBgn0004835, FBgn0015469, FBgn0021802" protein_coding_gene "transmembrane receptor protein serine/threonine kinase activity ; GO:0004675 | inferred from electronic annotation with InterPro:IPR000472, InterPro:IPR003605 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000333, InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from electronic annotation with InterPro:IPR000333 G-protein coupled receptor kinase activity ; GO:0004703 | inferred from sequence or structural similarity activin receptor activity, type I ; GO:0016361 | inferred from sequence or structural similarity activin binding ; GO:0048185 | inferred from direct assay transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement" determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity activin receptor signaling pathway ; GO:0032924 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement mushroom body development ; GO:0016319 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype positive regulation of pathway-restricted SMAD protein phosphorylation ; GO:0010862 | inferred from mutant phenotype eye-antennal disc morphogenesis ; GO:0007455 | inferred from genetic interaction with smo inferred from genetic interaction with ptc response to UV ; GO:0009411 | inferred from direct assay regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | non-traceable author statement signal transduction ; GO:0007165 | inferred from sequence or structural similarity neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from sequence or structural similarity positive regulation of BMP signaling pathway ; GO:0030513 | inferred from mutant phenotype negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype activin receptor complex ; GO:0048179 | inferred from sequence or structural similarity inferred from physical interaction with put "babo, Bab, CG8224, ATR-I, l(2)k16912, ATR-1, Atr-1, Atr-I, AtrI, Atr45A, STK-E, atr-I, Gprk-3, Babo, l(2)44Fd, Gprk3, Atf1, BABO" "IPR000472:Activin types I and II receptor domain, IPR000719:Protein kinase domain, IPR003605:GS domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR000333:Ser/Thr protein kinase, TGFB receptor, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG8224 11-Aug-17 DroID_v2017_08 "Drer\acvrl1, Drer\acvr1ba, Drer\bmpr1ba, Drer\tgfbr1b, Drer\pomk, Drer\LOC100331105, Drer\acvr1bb, Drer\acvr1l, Drer\bmpr1aa, Drer\tgfbr1a" - "Cele\sma-6, Cele\daf-1" "Xtro\acvr1, Xtro\tgfbr1, Xtro\acvr1c, Xtro\bmpr1a, Xtro\pomk, Xtro\bmpr1b, Xtro\acvr1b" "Mmus\Pomk, Mmus\Acvr1c, Mmus\Acvr1b, Mmus\Acvr1, Mmus\Tgfbr1, Mmus\Acvrl1, Mmus\Bmpr1b, Mmus\Bmpr1a" "Hsap\BMPR1B, Hsap\POMK, Hsap\ACVRL1, Hsap\ACVR1, Hsap\TGFBR1, Hsap\BMPR1A, Hsap\ACVR1C, Hsap\ACVR1B" " embryonic stage | 0-3 hr , adult stage | female , embryonic stage , adult stage && oogenesis stage | stage S10-11 , larval stage | third instar , embryonic stage -- adult stage " " nurse cell

, imaginal disc

, oocyte

" "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal,visible,dominant,neuroanatomy defective,mitotic cell cycle defective,germline clone,somatic clone,wild-type,developmental rate defective,decreased cell number,phototaxis defective,size defective,cell growth defective,viable,long lived,flight defective,progressive" "embryonic/larval brain,wing,head capsule,larva,anal pad,embryonic/larval anterior spiracle,imaginal disc,wing disc,optic lobe,axon & photoreceptor cell,embryonic brain,intersegmental nerve,abdominal segmental nerve,embryonic/larval neuromuscular junction,transverse nerve,brain,axon & photoreceptor cell R7,axon & photoreceptor cell R8,medulla,lamina,optic cartridge,medulla neuropil,medulla neuropil glial cell,lamina anlage glial cell,embryonic/larval optic lobe,medulla forming neuroblast,cell body rind of medulla,ganglion mother cell & larval optic lobe,lamina anlage,larval inner optic anlage,larval outer optic anlage,photoreceptor cell R7 & axon,photoreceptor cell R8 & axon,anterior pupal spiracle,leg,gamma-lobe & neuron | somatic clone,gamma-lobe & dendrite | somatic clone,germline clone,transmedullary neuron Tm20,somatic clone,photoreceptor cell R7,Kenyon cell,axon | somatic clone,dorsal cluster neuron & axon | somatic clone,dorsal cluster neuron & neurite | somatic clone,protocerebrum,fascicle,ellipsoid body,mushroom body gamma-lobe,distal medullary amacrine neuron Dm8,dorsal cluster neuron,adult mushroom body,embryonic/larval anal pad,olfactory neuron & axon,olfactory neuron & dendrite,antennal lobe & axon,calyx of mushroom body & axon,adult mushroom body & axon,adult antennal lobe projection neuron,persistent antennal lobe projection neuron,wing vein,eye,ommatidium,posterior compartment,wing vein | ectopic & wing | posterior compartmenten-e16E,wing blade,autophagic vacuoleMhc.PW,mesothoracic tergum,adult somatic muscle,progressive,lysosome | progressiveMhc.PW" FBgn0004456 mew multiple edematous wings http://flybase.org/reports/FBgn0004456 "FBgn0028276, FBgn0040161" protein_coding_gene receptor activity ; GO:0004872 | inferred from sequence or structural similarity cell adhesion molecule binding ; GO:0050839 | inferred from mutant phenotype receptor activity ; GO:0004872 | inferred from mutant phenotype extracellular matrix binding ; GO:0050840 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with mys cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity "salivary gland boundary specification ; GO:0007432 | inferred from mutant phenotype substrate adhesion-dependent cell spreading ; GO:0034446 | inferred from direct assay maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from genetic interaction with if cell adhesion ; GO:0007155 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from genetic interaction with Grip inferred from genetic interaction with kon cell-matrix adhesion ; GO:0007160 | inferred from sequence or structural similarity sensory perception of smell ; GO:0007608 | inferred from genetic interaction with sws ectodermal digestive tract morphogenesis ; GO:0048567 | traceable author statement cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from expression pattern inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement salivary gland development ; GO:0007431 | traceable author statement heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | traceable author statement cell adhesion mediated by integrin ; GO:0033627 | inferred from direct assay cell migration ; GO:0016477 | traceable author statement apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | non-traceable author statement salivary gland morphogenesis ; GO:0007435 | inferred from genetic interaction with βTub85D cell differentiation ; GO:0030154 | traceable author statement midgut development ; GO:0007494 | traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | non-traceable author statement axonal defasciculation ; GO:0007414 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement" integral component of plasma membrane ; GO:0005887 | inferred from direct assay integrin complex ; GO:0008305 | inferred from sequence or structural similarity integrin complex ; GO:0008305 | inferred from direct assay integrin complex ; GO:0008305 | non-traceable author statement lateral plasma membrane ; GO:0016328 | inferred from direct assay basal plasma membrane ; GO:0009925 | inferred from direct assay integrin complex ; GO:0008305 | inferred from sequence or structural similarity with HGNC:6139 focal adhesion ; GO:0005925 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "alphaPS1, mew, PS1, alpha[[PS1]], CG1771, CT5254, alpha-PS1, PS1alpha, aPS1, l(1)G0429, l(1)G0443, PSalpha1, alpha1Int, ItgaPS1" "IPR018184:Integrin alpha chain, C-terminal cytoplasmic region, conserved site, IPR000413:Integrin alpha chain, IPR013519:Integrin alpha beta-propellor, IPR013649:Integrin alpha-2, IPR032695:Integrin domain, IPR013517:FG-GAP repeat" CG1771 11-Aug-17 DroID_v2017_08 "Drer\itga6l, Drer\itga11b, Drer\itga9, Drer\itga3a, Drer\itga6a, Drer\itga10, Drer\itga3b, Drer\zmp:0000001082, Drer\si:dkey-32n7.4, Drer\itga2.2, Drer\itga1, Drer\itga11a, Drer\itgae.2, Drer\itgam, Drer\itga6b" - "Cele\ina-1, Cele\pat-2" "Xtro\itga2b.1, Xtro\itga6" "Mmus\Itga6, Mmus\Itgax, Mmus\Itgae, Mmus\Itga11, Mmus\Itga7, Mmus\Itgam, Mmus\Itga10, Mmus\Itga1, Mmus\Itga2, Mmus\Itgad, Mmus\Itgal, Mmus\Itga3" "Hsap\ITGAM, Hsap\ITGA7, Hsap\ITGAD, Hsap\ITGAX, Hsap\ITGAL, Hsap\ITGA3, Hsap\ITGAE, Hsap\ITGA11, Hsap\ITGA1, Hsap\ITGA6, Hsap\ITGA2, Hsap\ITGA10" " larval stage | third instar , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 11-12 " " adepithelial cell of dorsal mesothoracic disc

, posterior embryonic/larval midgut

, dorsal mesothoracic disc

, embryonic central nervous system

, peripodial epithelium

, tracheal pit

, ectoderm

, embryonic salivary gland

, anterior embryonic/larval midgut

" "lethal - all die before end of larval stage,recessive,some die during larval stage,viable,fertile,lethal,partially lethal - majority die,male,female,neuroanatomy defective,somatic clone,visible,heat sensitive" "filamentous actin | somatic clone,presumptive embryonic salivary gland,retina,somatic clone,wing,presumptive embryonic/larval digestive system,extended germ band embryo,midgut constriction,embryonic/larval midgut,fascicle,embryonic/larval visceral branch,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,intersegmental nerve,segmental nerve,muscle attachment site,anterior midgut primordium,salivary gland common duct primordium,embryonic/larval salivary gland,follicle cell,dorsal multidendritic neuron ddaC,somatic clone | third instar larval stage,dorsal wing blade,heat sensitive,photoreceptor,stage S14 oocyte,dorsal branch primordium" DRSC18971 E 0.244443446 0.617280166 -1.805192685 0.550427416 -0.086737417 -0.541777814 FBgn0000043 Act42A Actin 42A http://flybase.org/reports/FBgn0000043 - protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity phagocytosis ; GO:0006909 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype actin filament ; GO:0005884 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay "Actin, AFFX-Dros-ACTIN_M_r_at, Actin/BAP47, actin, BAP47, C, CG12051, act 42A, act42A, A, Act42A, Act, Act42a, Act42, 42A, ACT2_DROME, ArpB" "IPR020902:Actin/actin-like conserved site, IPR004000:Actin family, IPR004001:Actin, conserved site" CG12051 11-Aug-17 DroID_v2017_08 "Drer\actc1a, Drer\actb1, Drer\actc1b, Drer\si:ch73-187m15.4, Drer\actr10, Drer\si:ch211-241j12.3, Drer\acta1a, Drer\actb2, Drer\actr1, Drer\zgc:86725, Drer\ankrd52b, Drer\zgc:86709, Drer\acta2, Drer\acta1b" "Scer\ARP1, Scer\ACT1, Scer\ARP9, Scer\ARP4" "Cele\act-2, Cele\act-5, Cele\act-4, Cele\arp-1, Cele\act-1, Cele\act-3" "Xtro\actb, Xtro\actr10, Xtro\actc1, Xtro\act3, Xtro\acta2, Xtro\actr1a, Xtro\actg1, Xtro\ankrd52, Xtro\acta1" "Mmus\Actl7a, Mmus\Actrt2, Mmus\Actc1, Mmus\Actl11, Mmus\Actbl2, Mmus\Actg1, Mmus\Actrt1, Mmus\Actr1a, Mmus\Actl7b, Mmus\Actb, Mmus\Actl9, Mmus\Actr1b, Mmus\Acta1, Mmus\Actg2, Mmus\Actl10, Mmus\Actrt3, Mmus\Actr10, Mmus\Acta2" "Hsap\ACTL8, Hsap\ACTRT3, Hsap\POTEH, Hsap\ACTR10, Hsap\ACTL7B, Hsap\ACTA1, Hsap\POTEB, Hsap\ACTRT1, Hsap\ACTG2, Hsap\ACTR1A, Hsap\ACTBL2, Hsap\ACTL10, Hsap\POTED, Hsap\POTEB2, Hsap\ACTL9, Hsap\ACTG1, Hsap\ACTRT2, Hsap\POTEG, Hsap\ACTR1B, Hsap\ACTA2, Hsap\POTEI, Hsap\ACTL7A, Hsap\POTEC, Hsap\POTEA, Hsap\POTEF, Hsap\POTEE, Hsap\ACTC1, Hsap\ACTB, Hsap\POTEJ" " embryonic stage | blastoderm , embryonic stage " " embryonic/larval midgut

, gonad

, supraesophageal ganglion

, ventral nerve cord

, embryonic/larval proventriculus

" "lethal,partially lethal - majority die,visible" "chaeta,supernumerary,trichogen cell,mesothoracic tergum,wing sensillum,external sensory organ" DRSC04835 IE -1.088303677 -3.479833708 -0.455146012 -1.65413146 0.596505723 1.478638891 FBgn0266581 pit pitchoune http://flybase.org/reports/FBgn0266581 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD:S000004903 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 cell proliferation ; GO:0008283 | inferred from mutant phenotype cell growth ; GO:0016049 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay "pit, CG6375, PIT, DmRH15, Pit, hel93F, Hel93F" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR025313:Domain of unknown function DUF4217, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG6375 11-Aug-17 DroID_v2017_08 "Drer\ddx18, Drer\ddx10" "Scer\MSS116, Scer\HCA4, Scer\HAS1" "Cele\Y23H5B.6, Cele\B0511.6" "Xtro\ddx18, Xtro\ddx10" "Mmus\Ddx10, Mmus\Ddx18, Mmus\Kctd19" "Hsap\KCTD19, Hsap\DDX10, Hsap\DDX18" " embryonic stage | early , adult stage && oogenesis stage , embryonic stage | stage 16 , oogenesis stage | stage >= S4 && adult stage | female , larval stage , embryonic stage | stage 11 , embryonic stage | stage >=11 , embryonic stage | gastrula " "

ubiquitous , germarium

, Malpighian tubule

, egg chamber

, imaginal disc | ubiquitous

, anal plate

, anterior midgut proper primordium

, embryonic/larval salivary gland | precursor

, epithelial sheath &&of embryonic/larval midgut

, epithelial sheath &&of embryonic/larval hindgut

, gonadal sheath

, embryonic/larval midgut

, posterior midgut proper primordium

, mesoderm

" FBgn0005638 slbo slow border cells http://flybase.org/reports/FBgn0005638 "FBgn0013451, FBgn0015734, FBgn0016064, FBgn0016065, FBgn0016066" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR031106 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay" border follicle cell migration ; GO:0007298 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cell fate specification ; GO:0001708 | traceable author statement positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from physical interaction with Stat92E border follicle cell migration ; GO:0007298 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Slbo, Dm-c/EBP, slobo, DmC/EBP, C/EBP, DC/EBP, fs(2)ry8, fs(2)ry7, fs(2)8, fs(2)7, CG4354, slbo, SLBO, DM8" "IPR004827:Basic-leucine zipper domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG4354 11-Aug-17 DroID_v2017_08 "Drer\cebpg, Drer\cebpa, Drer\cebpd, Drer\cebp1, Drer\cebpb" - "Cele\ces-2, Cele\cebp-1, Cele\cebp-2, Cele\zip-8, Cele\zip-4" "Xtro\cebpg, Xtro\cebpa" "Mmus\Cebpb, Mmus\Cebpg, Mmus\Cebpe, Mmus\Cebpa, Mmus\Cebpd" "Hsap\CEBPB, Hsap\CEBPD, Hsap\CEBPG, Hsap\CEBPE, Hsap\CEBPA" " adult stage && oogenesis stage | female , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S10 , embryonic stage | 8-16 hr " " ovary

, border follicle cell

, centripetally migrating follicle cell

" " embryonic stage | 9-10 hr , embryonic stage | mid-late , adult stage && oogenesis stage | stage S9-10 , adult stage && oogenesis stage | stage S10 " " embryonic/larval anterior spiracle

, embryonic/larval midgut

, embryonic/larval proventriculus

, embryonic/larval hindgut

, embryonic/larval salivary gland

, border follicle cell

, epidermis

, centripetally migrating follicle cell

, embryonic/larval foregut

" "female sterile,recessive,cell migration defective,fertile,poor,developmental rate defective,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,female fertile,wild-type,visible,lethal - all die before end of pupal stage,some die during pupal stage" "border follicle cell,egg chamber,polar follicle cell,somatic clone,wing,egg chamber | oogenesis stage S10,border follicle cell | oogenesis stage S10" DRSC04716 IE 1.368389206 -1.83883004 2.0455141 -1.599451076 0.070126022 0.737347815 FBgn0028789 Doc1 Dorsocross1 http://flybase.org/reports/FBgn0028789 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay" heart development ; GO:0007507 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype cardiocyte differentiation ; GO:0035051 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype determination of wing disc primordium ; GO:0035294 | inferred from mutant phenotype anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR002070, InterPro:IPR018186" "Doc, Dm-DOC1, Tb66F2, Ect2, CG5133, Doc1, doc, doc1, TBX6" "IPR001699:Transcription factor, T-box, IPR002070:Transcription factor, Brachyury, IPR008967:p53-like transcription factor, DNA-binding, IPR018186:Transcription factor, T-box, conserved site" CG5133 11-Aug-17 DroID_v2017_08 "Drer\eomesb, Drer\ta, Drer\tbx3a, Drer\tbx5a, Drer\tbx21, Drer\tbx1, Drer\tbx19, Drer\tbx16, Drer\tbx2b, Drer\tbx22, Drer\tbx5b, Drer\tbr1a, Drer\tbr1b, Drer\tbx4, Drer\tbx6l, Drer\tb, Drer\mgaa, Drer\tbx20, Drer\tbx6, Drer\eomesa, Drer\tbx18, Drer\tbx2a, Drer\tbx3b" - "Cele\tbx-2, Cele\mab-9, Cele\tbx-31, Cele\tbx-35, Cele\mls-1" "Xtro\vegt, Xtro\tbx2, Xtro\tbx5, Xtro\tbx18, Xtro\tbx15, Xtro\tbx22, Xtro\tbx6, Xtro\t, Xtro\tbx4, Xtro\mga, Xtro\eomes, Xtro\tbr1, Xtro\tbx3, Xtro\t2, Xtro\tbx1, Xtro\tbx20" "Mmus\Tbx2, Mmus\Tbx6, Mmus\Mga, Mmus\Tbx10, Mmus\Tbx15, Mmus\Tbx3, Mmus\Tbx21, Mmus\T, Mmus\Tbx1, Mmus\Tbx4, Mmus\Tbr1, Mmus\Eomes, Mmus\Tbx19, Mmus\Tbx5, Mmus\Tbx22, Mmus\Tbx18, Mmus\Tbx20" "Hsap\TBX15, Hsap\TBX21, Hsap\TBX4, Hsap\TBX6, Hsap\MGA, Hsap\TBX5, Hsap\TBX18, Hsap\TBR1, Hsap\TBX20, Hsap\TBX2, Hsap\TBX19, Hsap\EOMES, Hsap\TBX22, Hsap\TBX10, Hsap\T, Hsap\TBX3, Hsap\TBX1" " adult stage | male , embryonic stage--pupal stage , embryonic stage | cellular blastoderm " dorsal ectoderm anlage

" embryonic stage | stage 5-11 , embryonic stage | stage 5-15 , embryonic stage | stage 15-16 , embryonic stage , embryonic stage | stage 9-16 " " organism | dorso-lateral

, amnioserosa

, dorsal pouch

, abdominal lateral pentascolopidial chordotonal organ lch5

, cardioblast | subset

, procephalic neurogenic region

, mesoderm | restricted

, embryonic anterior Malpighian tubule

, parasegment && ectoderm && mesoderm | dorsal & restricted

" viable FBgn0030608 Lsd-2 Lipid storage droplet-2 http://flybase.org/reports/FBgn0030608 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with klar regulation of transport ; GO:0051049 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from expression pattern inferred from mutant phenotype lipid metabolic process ; GO:0006629 | inferred from mutant phenotype lipid transport ; GO:0006869 | inferred from expression pattern lipid particle transport along microtubule ; GO:0031887 | inferred from mutant phenotype negative regulation of lipid catabolic process ; GO:0050995 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype sequestering of triglyceride ; GO:0030730 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from expression pattern lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "145098_at, LSD2, CG9057, Lsd2, LSD-2, Lsd-2, LSP-2, plin2, PLIN2, DmPLIN2" IPR004279:Perilipin CG9057 11-Aug-17 DroID_v2017_08 "Drer\plin2, Drer\zgc:77486, Drer\zgc:162150, Drer\si:rp71-61h23.4" - - "Xtro\plin1, Xtro\plin3" "Mmus\Plin2, Mmus\Plin3, Mmus\Plin1, Mmus\Plin4, Mmus\Plin5" "Hsap\PLIN2, Hsap\PLIN4, Hsap\PLIN3, Hsap\PLIN5, Hsap\PLIN1" " larval stage | third instar , embryonic stage | late , embryonic stage | stage 5 , embryonic stage | stage 13 , embryonic stage | stage 4 " " fat body

, fat body && midgut | anterior

, germline cell

, amnioserosa

, organism | ubiquitous " larval stage | third instar fat body

"viable,fertile,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "lipid particle | embryonic stage | maternal effect,fat body,lipid particle,embryonic/larval fat body,nurse cell,lipid particle | embryonic stage,lipid droplet & larval oenocyteppl.PP,mesothoracic tergum" FBgn0000826 png pan gu http://flybase.org/reports/FBgn0000826 FBgn0024363 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | traceable author statement "regulation of mitotic cell cycle ; GO:0007346 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay egg activation ; GO:0007343 | inferred from mutant phenotype positive regulation of mitotic cell cycle, embryonic ; GO:0045977 | inferred from mutant phenotype" serine/threonine protein kinase complex ; GO:1902554 | inferred from physical interaction with plu "Png, EG:8D8.5, PNG, CG11420, fs(1)M2, pan-gnu, png" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG11420 11-Aug-17 DroID_v2017_08 "Drer\si:dkey-192d15.2, Drer\nek11, Drer\map3k2, Drer\si:ch211-285c6.3, Drer\nek8, Drer\LOC107980443, Drer\si:ch211-217i17.1, Drer\nek12, Drer\nek1, Drer\nek4, Drer\LOC101885992, Drer\si:ch211-285c6.2, Drer\LOC100536894, Drer\map3k3" "Scer\PKH3, Scer\KIN3" "Cele\T07F12.4, Cele\Y106G6A.1" "Xtro\nek5, Xtro\nek3, Xtro\nek9, Xtro\nek8, Xtro\nek4, Xtro\map3k2, Xtro\stkld1, Xtro\nek1, Xtro\map3k3, Xtro\nek10" "Mmus\Nek1, Mmus\Nek3, Mmus\Nek10, Mmus\Nek4, Mmus\Nek8, Mmus\Nek11, Mmus\Nek5, Mmus\Nek9, Mmus\Stkld1" "Hsap\NEK5, Hsap\NEK8, Hsap\NEK3, Hsap\NEK9, Hsap\NEK11, Hsap\NEK4, Hsap\NEK1, Hsap\STKLD1, Hsap\NEK10" " embryonic stage | 0-3 hr , adult stage | female " " egg stage | unfertilized egg , embryonic stage | 0-12 hr " unfertilized egg

"lethal,maternal effect,female sterile,viable,fertile,wild-type,mitotic cell cycle defective,meiotic cell cycle defective" "nuclear chromosome,nucleus,polar body nucleus,nucleus | embryonic stage,nucleus & unfertilized egg,nucleus | blastoderm stage | maternal effect,egg & nucleus,pronucleus,annulate lamellae" FBgn0261988 Gprk2 G protein-coupled receptor kinase 2 http://flybase.org/reports/FBgn0261988 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000239, InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement G-protein coupled receptor kinase activity ; GO:0004703 | inferred from mutant phenotype G-protein coupled receptor kinase activity ; GO:0004703 | inferred from sequence or structural similarity" signal transduction ; GO:0007165 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | inferred from mutant phenotype regulation of Toll signaling pathway ; GO:0008592 | inferred from genetic interaction with Tl imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from genetic interaction with fu inferred from genetic interaction with smo inferred from genetic interaction with ptc inferred from genetic interaction with Su(fu) protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype regulation of smoothened signaling pathway ; GO:0008589 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of cAMP-mediated signaling ; GO:0043950 | inferred from genetic interaction with Gαi inferred from genetic interaction with Gαs defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype oocyte morphogenesis ; GO:0048601 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "gprk2, Gprk2, 154978_at, CG17998, Gprk-2, nosh" "IPR000239:GPCR kinase, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR011009:Protein kinase-like domain, IPR016137:RGS domain, IPR017441:Protein kinase, ATP binding site" CG17998 11-Aug-17 DroID_v2017_08 "Drer\grk4, Drer\grk6, Drer\grk1a, Drer\grk1b, Drer\grk7b, Drer\adrbk2, Drer\grk5, Drer\grk5l, Drer\grk7a" - Cele\grk-1 "Xtro\grk5, Xtro\grk7, Xtro\grk1, Xtro\grk4, Xtro\grk6" "Mmus\Grk6, Mmus\Grk4, Mmus\Grk3, Mmus\Grk1, Mmus\Grk2, Mmus\Grk5" "Hsap\GRK4, Hsap\GRK7, Hsap\GRK3, Hsap\GRK2, Hsap\GRK6, Hsap\GRK1, Hsap\GRK5" " larval stage | third instar , oogenesis stage && adult stage | female , embryonic stage | early , embryonic stage " ovary

" oogenesis stage && adult stage | female , larval stage , adult stage , adult stage && oogenesis stage , embryonic stage -- adult stage , larval stage && adult stage " " oocyte

, dorsal mesothoracic disc

, Kenyon cell

, longitudinal connective

, adult head

, larval central nervous system

, larval corpus allatum

, adult central nervous system

,

ubiquitous , optic lobe

, germarium

, follicle cell

, mushroom body

, retina

, mushroom body | restricted

, ovary

, neuron

, mushroom body alpha-lobe

, nurse cell

, ellipsoid body

" DRSC16682 I -1.711341334 -0.622063111 -0.283934963 -0.032537066 0.304681386 0.75792917 FBgn0004893 bowl brother of odd with entrails limited http://flybase.org/reports/FBgn0004893 "FBgn0022034, FBgn0014041" protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with odd" "embryonic hindgut morphogenesis ; GO:0048619 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:P23803 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype embryonic foregut morphogenesis ; GO:0048617 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with UniProtKB:P23803 wing disc development ; GO:0035220 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:P23803 terminal region determination ; GO:0007362 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with UniProtKB:P23803 imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with odd "Bowl, 17-29-5, Su(tor)2-1, l(2)c, org2, CG10021, bowl, BOWL" IPR013087:Zinc finger C2H2-type CG10021 11-Aug-17 DroID_v2017_08 "Drer\klf11a, Drer\klf15, Drer\osr1, Drer\znf148, Drer\egr2b, Drer\znf281b, Drer\egr4, Drer\osr2, Drer\sp2, Drer\si:ch211-117k10.3, Drer\egr1, Drer\znf281a" "Scer\MSN4, Scer\MSN2, Scer\FZF1" "Cele\egrh-3, Cele\odd-1, Cele\egrh-1, Cele\odd-2" "Xtro\egr1, Xtro\egr3, Xtro\klf11, Xtro\sp2, Xtro\klf15, Xtro\egr2, Xtro\osr1, Xtro\osr2" "Mmus\Sp2, Mmus\Egr4, Mmus\Egr3, Mmus\Osr1, Mmus\Osr2, Mmus\Klf11, Mmus\Egr1, Mmus\Klf15" "Hsap\EGR2, Hsap\KLF11, Hsap\EGR4, Hsap\ZBTB4, Hsap\KLF15, Hsap\EGR1, Hsap\OSR2, Hsap\OSR1, Hsap\ZBTB38, Hsap\ZBTB2, Hsap\EGR3, Hsap\SP2" " embryonic stage | stage 5 , embryonic stage , embryonic stage | stage 8-12 , embryonic stage | stage 7-9 , larval stage | third instar , embryonic stage | stage 11 , embryonic stage | stage 8-11 , pupal stage , embryonic stage | stage 7 , embryonic stage | stage 7-12 , embryonic stage | >= 2 hr , embryonic stage | stage 9 , embryonic stage | stage 11-14 " " organism | 80-100% egg length

, organism | pair rule

, posterior embryonic/larval midgut

,

0-10% egg length , amnioproctodeal invagination

, organism | 0-10% egg length

, ventral thoracic disc | restricted

, cephalic furrow

, labral segment

, organism | 80% egg length & ventral

, cephalic furrow | anterior to

, stomodeum

, organism | 70% egg length & dorsal

, embryonic/larval hindgut

,

terminal , leg | restricted

,

segment polarity , anterior embryonic/larval midgut

, embryonic/larval foregut

, organism | 20-100% egg length

" "lethal,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,semidominant,maternal effect,somatic clone,viable" "embryonic mandibular segment,embryonic maxillary segment,embryonic/larval hindgut,embryonic/larval proventriculus,joint,tarsal segment,embryonic large intestine,embryonic small intestine,embryonic rectum,lateral process,cephalopharyngeal skeleton,somatic clone,tarsal segment 2,tarsal segment 3,tarsal segment 4,metatarsus,pretarsus,abdominal 2 ventral denticle belt,abdominal 6 ventral denticle belt,embryonic hindgut,adult cuticle & leg | somatic clone,eye disc,peripodial epithelium & dorsal mesothoracic disc | somatic clone | first instar larval stage,eye-antennal disc,antenna,ectopic,eye,prescutum,embryonic dorsal epidermis,embryonic proventriculus,keyhole structure,sex comb,thorax,chaeta,supernumerary" DRSC00805 E 0.132752495 -0.020690858 0.10548997 -1.875326317 0.192595915 0.752246115 FBgn0039175 beta-PheRS "Phenylalanyl-tRNA synthetase, beta-subunit" http://flybase.org/reports/FBgn0039175 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR004531, InterPro:IPR005147 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR005146, InterPro:IPR005147 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR005147 phenylalanine-tRNA ligase activity ; GO:0004826 | traceable author statement aminoacyl-tRNA editing activity ; GO:0002161 | inferred from mutant phenotype phenylalanine-tRNA ligase activity ; GO:0004826 | inferred from direct assay" phenylalanyl-tRNA aminoacylation ; GO:0006432 | traceable author statement phenylalanyl-tRNA aminoacylation ; GO:0006432 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004531 cytoplasm ; GO:0005737 | traceable author statement "CG5706, beta-PheRS" "IPR004531:Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic, IPR005146:B3/B4 tRNA-binding domain, IPR005147:tRNA synthetase, B5-domain, IPR009061:Putative DNA-binding domain, IPR020825:Phenylalanyl-tRNA synthetase, B3/B4" CG5706 11-Aug-17 DroID_v2017_08 "Drer\farsb, Drer\lrrc47" Scer\FRS1 Cele\fars-3 "Xtro\lrrc47, Xtro\farsb" "Mmus\Farsb, Mmus\Lrrc47" "Hsap\LRRC47, Hsap\FARSB" "lethal,female sterile" FBgn0262760 Mst77Y-11Psi Male-specific pseudogene 77Y 11 http://flybase.org/reports/FBgn0262760 pseudogene_attribute - - - Mst77Y-11Psi - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0262870 axo axotactin http://flybase.org/reports/FBgn0262870 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 transmission of nerve impulse ; GO:0019226 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence or structural similarity "axo, CG43225, CG42664, CG13715, CG32234, CT1277, CG18296, CG13717" "IPR013032:EGF-like, conserved site, IPR000742:EGF-like domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001791:Laminin G domain, IPR002223:Pancreatic trypsin inhibitor Kunitz domain" CG43225 11-Aug-17 DroID_v2017_08 "Drer\tfpia, Drer\cntnap5l, Drer\cp, Drer\ambp, Drer\col6a4a, Drer\spint1b, Drer\pcolcea, Drer\cntnap1, Drer\tfpi2, Drer\cntnap2a, Drer\pcolceb, Drer\f8, Drer\hephl1b, Drer\si:dkey-117n7.5, Drer\hephl1a, Drer\cntnap5b, Drer\spint2, Drer\spint1a, Drer\cntnap2b, Drer\cntnap3, Drer\cntnap5a, Drer\si:dkeyp-73b11.8" - "Cele\nlr-1, Cele\W02G9.4, Cele\itx-1, Cele\sol-2" "Xtro\cntnap4, Xtro\tfpi2, Xtro\spint2, Xtro\ambp, Xtro\spint1, Xtro\cntnap1" "Mmus\Eppin, Mmus\Cntnap2, Mmus\Tfpi, Mmus\Tfpi2, Mmus\Spint4, Mmus\Spint2, Mmus\Cntnap5c, Mmus\Wfdc6a, Mmus\Cntnap5a, Mmus\Spint1, Mmus\Cntnap5b, Mmus\Cp, Mmus\Ambp, Mmus\Spint3, Mmus\Spint5, Mmus\Cntnap3, Mmus\Heph, Mmus\Wfdc6b, Mmus\Cntnap1, Mmus\Wfdc8, Mmus\Cntnap4, Mmus\Hephl1" "Hsap\SPINT1, Hsap\CNTNAP4, Hsap\CNTNAP2, Hsap\CNTNAP1, Hsap\AMBP, Hsap\LOC100289279, Hsap\SPINT2, Hsap\SPINT3, Hsap\TFPI, Hsap\CNTNAP3B, Hsap\WFDC8, Hsap\CP, Hsap\CNTNAP3, Hsap\CNTNAP5, Hsap\HEPH, Hsap\SPINT4, Hsap\TFPI2, Hsap\EPPIN-WFDC6, Hsap\HEPHL1, Hsap\WFDC6" " embryonic stage | stage >=13 , larval stage " " medial intersegmental nerve root glial cell

, glial cell | subset

, interface glial cell

, larval central nervous system

segmentally repeated , embryonic central nervous system

segmentally repeated " embryonic stage " embryonic peripheral nervous system | restricted

, ventral nerve cord

, embryonic brain

, neuron

" FBgn0030897 Frq1 Frequenin 1 http://flybase.org/reports/FBgn0030897 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from direct assay calcium sensitive guanylate cyclase activator activity ; GO:0008048 | inferred from sequence or structural similarity with HGNC:9937 inferred from direct assay neurotransmitter secretion ; GO:0007269 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from sequence or structural similarity with Frq2 chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype - "frq1, CG5744, Frq, HL-II, Frq1, frq" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG5744 11-Aug-17 DroID_v2017_08 "Drer\kcnip1a, Drer\usp32, Drer\hpcal4, Drer\si:ch211-145b13.5, Drer\rcvrnb, Drer\ncalda, Drer\vsnl1b, Drer\efcab1, Drer\kcnip2, Drer\ncaldb, Drer\si:ch211-103a14.5, Drer\rcvrn3, Drer\guca1e, Drer\guca1c, Drer\hpcal1, Drer\guca1b, Drer\kcnip3b, Drer\kcnip4, Drer\guca1a, Drer\ncs1b, Drer\guca1g, Drer\rcvrn2, Drer\rcvrna, Drer\kcnip1b, Drer\hpca, Drer\guca1d, Drer\ncs1a, Drer\vsnl1a, Drer\si:ch211-245j22.3" Scer\FRQ1 "Cele\ncs-2, Cele\ncs-3, Cele\ncs-1" "Xtro\guca1b, Xtro\ncald, Xtro\guca1a, Xtro\ncs1, Xtro\efcab1, Xtro\vsnl1, Xtro\hpca, Xtro\rcvrn.2, Xtro\guca1c, Xtro\kcnip1, Xtro\kcnip3, Xtro\kcnip2, Xtro\hpcal1, Xtro\kcnip4" "Mmus\Ncald, Mmus\Rcvrn, Mmus\Kcnip1, Mmus\Kcnip4, Mmus\Usp32, Mmus\1700109H08Rik, Mmus\Guca1b, Mmus\Vsnl1, Mmus\Kcnip2, Mmus\Hpcal4, Mmus\Guca1a, Mmus\Ncs1, Mmus\Efcab1, Mmus\Kcnip3, Mmus\Hpca, Mmus\Hpcal1" "Hsap\USP32, Hsap\NCS1, Hsap\EFCAB1, Hsap\GUCA1B, Hsap\RCVRN, Hsap\GUCA1A, Hsap\NCALD, Hsap\KCNIP1, Hsap\HPCA, Hsap\KCNIP3, Hsap\GUCA1C, Hsap\VSNL1, Hsap\KCNIP2, Hsap\HPCAL4, Hsap\HPCAL1, Hsap\KCNIP4" " embryonic stage , adult stage , larval stage " " embryonic peripheral nervous system

, adult brain

, central nervous system

, synapse

, neuromuscular junction

, larval brain

, lamina

, neuropil

" "neuroanatomy defective,heat sensitive,viable,neurophysiology defective,locomotor behavior defective" "bouton,heat sensitive,motor neuron,embryonic/larval neuromuscular junction,type I bouton,NMJ bouton" FBgn0014861 Mcm2 Minichromosome maintenance 2 http://flybase.org/reports/FBgn0014861 FBgn0011511 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008045, InterPro:IPR018525 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008045, InterPro:IPR018525 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR008045 lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA replication ; GO:0006260 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008045 MCM complex ; GO:0042555 | inferred from electronic annotation with InterPro:IPR008045 "MCM2, dMCM2, DmMcm2, DmMCM2, PCR3, l(3)rL074, CG7538, Mcm2, McM2, DmeMCM2, MCM2_DROME, MCM2-7, dMcm2, mcm2-7" "IPR018525:Mini-chromosome maintenance, conserved site, IPR001208:MCM domain, IPR008045:DNA replication licensing factor Mcm2, IPR012340:Nucleic acid-binding, OB-fold, IPR033762:MCM OB domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027925:MCM N-terminal domain, IPR031327:Mini-chromosome maintenance protein" CG7538 11-Aug-17 DroID_v2017_08 "Drer\mcm9, Drer\mcm2" Scer\MCM2 Cele\mcm-2 "Xtro\mcm9, Xtro\mcm2" "Mmus\Mcm2, Mmus\Mcm9" "Hsap\MCM9, Hsap\MCM2" " embryonic stage | early , embryonic stage , embryonic stage | stage 8 " " central nervous system

, embryonic/larval digestive system

, embryonic peripheral nervous system

,

ubiquitous , Malpighian tubule

" "lethal,recessive,some die during immature adult stage,neuroanatomy defective,viable,visible" "central nervous system,imaginal disc,nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0028381 Decay Death executioner caspase related to Apopain/Yama http://flybase.org/reports/FBgn0028381 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity with Dcp-1 inferred from direct assay cysteine-type endopeptidase activity involved in apoptotic process ; GO:0097153 | inferred from biological aspect of ancestor with PANTHER:PTN000047947 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001309, InterPro:IPR002138, InterPro:IPR011600, InterPro:IPR016129 larval midgut histolysis ; GO:0035069 | NOT inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype programmed cell death ; GO:0012501 | traceable author statement" cytoplasm ; GO:0005737 | inferred from direct assay "caspase 3, Caspase-3, caspase-3, Decay, CG14902, Drosophila executioner caspase related to Apopain/Yama, DECAY, Casp3, cas3, decay, Cas3, CC3, CAS3, CC-3" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR015917:Peptidase C14A, caspase catalytic domain, IPR016129:Peptidase family C14A, His active site, IPR029030:Caspase-like domain, IPR033139:Peptidase family C14A, cysteine active site, IPR033176:Caspase DECAY" CG14902 11-Aug-17 DroID_v2017_08 "Drer\zgc:171731, Drer\si:dkey-103e21.5, Drer\casp9, Drer\pea15, Drer\LOC101886133, Drer\casp6l1, Drer\casp6, Drer\LOC100331324, Drer\si:ch211-195h23.3, Drer\caspbl, Drer\LOC798445, Drer\casp8l2, Drer\casp8, Drer\casp6l2, Drer\cflara, Drer\casp3b, Drer\casp7, Drer\gbp3, Drer\caspxa, Drer\zgc:194469, Drer\casp2, Drer\caspa, Drer\casp3a, Drer\caspb, Drer\casp8l1" - "Cele\ced-3, Cele\csp-1" "Xtro\pea15, Xtro\casp7, Xtro\casp1, Xtro\casp3, Xtro\casp10, Xtro\casp2, Xtro\casp6, Xtro\casp9, Xtro\LOC733553" "Mmus\Casp7, Mmus\Casp8, Mmus\Casp1, Mmus\Casp6, Mmus\Casp4, Mmus\Casp12, Mmus\Casp3, Mmus\Pycard, Mmus\Casp14, Mmus\Pea15a, Mmus\Casp9, Mmus\Casp2, Mmus\Cflar" "Hsap\CASP7, Hsap\CASP10, Hsap\CASP14, Hsap\CASP4, Hsap\CASP8, Hsap\CARD16, Hsap\CASP2, Hsap\CASP6, Hsap\CARD17, Hsap\CARD8, Hsap\CFLAR, Hsap\PYCARD, Hsap\CASP5, Hsap\PEA15, Hsap\CASP1, Hsap\CASP9, Hsap\CASP3, Hsap\CARD18" " embryonic stage | stage >=13 , larval stage | third instar , embryonic stage | stage 1-7 , adult stage && oogenesis stage , embryonic stage -- adult stage " " embryonic/larval midgut

,

ubiquitous , oocyte

, nurse cell

, eye disc

, larval brain

, egg chamber

, embryonic/larval salivary gland

" "viable,fertile,visible,male semi-sterile" "trichogen cell,male accessory gland,ejaculatory duct,seminal vesicle" DRSC16930 EK -0.227542395 -0.01868415 1.045984036 1.566359268 -0.759995687 1.895748115 FBgn0004369 Ptp99A Protein tyrosine phosphatase 99A http://flybase.org/reports/FBgn0004369 "FBan0002005, FBan0011517, FBgn0010251, FBgn0039661, FBgn0039662, FBgn0040621, FBgn0040622" protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with protein_id:CAA38067.1 transmembrane receptor protein tyrosine phosphatase activity ; GO:0005001 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with HGNC:9671 "motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Lar, Ptp10D motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Ptp69D protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with protein_id:CAA38067.1 protein dephosphorylation ; GO:0006470 | non-traceable author statement axonal defasciculation ; GO:0007414 | traceable author statement defasciculation of motor neuron axon ; GO:0007415 | inferred from genetic interaction with Ptp69D regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "DPTP99A, CT6383, R-PTP 99A, CG11516, CG2005, PTP99A, dptp99A, DPTP[[99A]], CG11515, CG11517, Ptp99A, ptp99A" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR003961:Fibronectin type III, IPR016130:Protein-tyrosine phosphatase, active site, IPR003595:Protein-tyrosine phosphatase, catalytic, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029021:Protein-tyrosine phosphatase-like, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain" CG11516 11-Aug-17 DroID_v2017_08 "Drer\ptprga, Drer\ptprd, Drer\ptprfa, Drer\ptpn5, Drer\ptpn2b, Drer\ca16c, Drer\ptpn18, Drer\ptprz1b, Drer\ca16b, Drer\ptprr, Drer\ptpn2a, Drer\ptprfb, Drer\ptpn22, Drer\ptprsa, Drer\ptpn1" "Scer\PTP2, Scer\PTP1, Scer\PTP3" "Cele\K07F5.8, Cele\F20H11.4, Cele\C17H12.3, Cele\F10G8.1, Cele\F25H5.7, Cele\T27A3.5, Cele\C55B7.3, Cele\C33H5.16, Cele\C02B10.6, Cele\F38H4.4, Cele\T28F4.3, Cele\ZK616.65, Cele\F47B3.6, Cele\F36H12.10, Cele\egg-3, Cele\C33F10.8, Cele\M04G7.2, Cele\Y48G9A.9, Cele\C46A5.1, Cele\ZK354.8, Cele\Y71F9AL.4, Cele\ptp-4, Cele\F55F8.7, Cele\T22C1.8, Cele\F55H12.5, Cele\F20B6.1, Cele\ptp-3, Cele\ZK484.7, Cele\F36H1.3, Cele\Y39A3A.4, Cele\R10F2.6, Cele\B0207.1, Cele\F47B3.1" "Xtro\ptpn12, Xtro\ptpn22, Xtro\ptpn1, Xtro\ptpn2, Xtro\ptprr, Xtro\ptprz1, Xtro\ptprd, Xtro\ptpn23, Xtro\ptprf, Xtro\ptprs" "Mmus\Ptpn2, Mmus\Ptpn18, Mmus\Ptpn22, Mmus\Ptprc, Mmus\Ptprs, Mmus\Ptprr, Mmus\Ptpn7, Mmus\Ptpn12, Mmus\Ptprd, Mmus\Ptpn20, Mmus\Ptprz1, Mmus\Ptpn5, Mmus\Ptpn23, Mmus\Ptpn1, Mmus\Ptprg, Mmus\Ptprf" "Hsap\PTPN7, Hsap\PTPRD, Hsap\PTPN2, Hsap\PTPN23, Hsap\PTPRF, Hsap\PTPN20, Hsap\PTPN22, Hsap\PTPRR, Hsap\PTPRC, Hsap\PTPN18, Hsap\PTPN1, Hsap\PTPN5, Hsap\PTPN12, Hsap\PTPRG, Hsap\PTPRZ1, Hsap\PTPRS" " larval stage | first instar , embryonic stage | stage 12-14 , embryonic stage , embryonic stage | stage 12 , adult stage , embryonic stage && adult stage , embryonic stage&&adult stage , embryonic stage | stage >=13 , embryonic stage | early , larval stage " " RP1 neuron

, aCC neuron

, central nervous system | restricted

, adult head

, RP2 neuron

, pCC neuron

, VUM neuron

, embryonic central nervous system | segmentally repeated pattern

, imaginal disc

, RP3 neuron

" " embryonic stage | stage 12-16 , embryonic stage | stage 12-17 , embryonic stage | stage >=13 , embryonic stage | stage 12-14 , embryonic stage | stage >=12 , embryonic stage | stage 12 , embryonic stage , embryonic stage | stage 13-17 " " segmental nerve

, longitudinal connective

, intersegmental nerve

, embryonic central nervous system

, posterior commissure

, aCC neuron

, anterior commissure

, commissure

, RP2 neuron

, RP1 neuron

, supraesophageal ganglion

, pCC neuron

, RP3 neuron

, embryonic/larval trachea

, neuron

, ventral nerve cord

, central nervous system | restricted

" "viable,fertile,chemical sensitive" "intersegmental nerve,abdominal segmental nerve" DRSC14319 K 1.916851367 -0.487310118 FBgn0014143 croc crocodile http://flybase.org/reports/FBgn0014143 FBgn0004894 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122 DNA binding ; GO:0003677 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456 specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Dmfd1, FD1, fd78E, fd1, CG5069, croc, FoxC" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR018122:Fork head domain conserved site1, IPR030456:Fork head domain conserved site 2" CG5069 11-Aug-17 DroID_v2017_08 "Drer\foxl1, Drer\foxc1a, Drer\foxd1, Drer\foxa1, Drer\foxa2, Drer\foxe1, Drer\foxd2, Drer\foxd3, Drer\zgc:162612, Drer\foxa, Drer\foxa3, Drer\foxc1b, Drer\foxd5, Drer\foxe3" "Scer\HCM1, Scer\FKH1" "Cele\unc-130, Cele\pha-4, Cele\fkh-6, Cele\fkh-2" "Xtro\foxd4l1.1, Xtro\foxd1, Xtro\foxc2, Xtro\foxc1, Xtro\foxi4.2, Xtro\foxe1, Xtro\foxa1, Xtro\foxa2, Xtro\foxd3, Xtro\foxl1, Xtro\foxe3, Xtro\foxa4, Xtro\foxd2" "Mmus\Foxd4, Mmus\Foxd3, Mmus\Foxe1, Mmus\Foxa2, Mmus\Foxl1, Mmus\Foxa3, Mmus\Foxc2, Mmus\Foxd1, Mmus\Foxa1, Mmus\Foxs1, Mmus\Foxc1, Mmus\Foxd2" "Hsap\FOXA1, Hsap\FOXD4L6, Hsap\FOXI3, Hsap\FOXD4L1, Hsap\FOXD4L5, Hsap\FOXE1, Hsap\FOXS1, Hsap\FOXD1, Hsap\FOXD4, Hsap\FOXA2, Hsap\FOXC1, Hsap\FOXD3, Hsap\FOXC2, Hsap\FOXD4L3, Hsap\FOXD4L4, Hsap\FOXL1, Hsap\FOXA3, Hsap\FOXD2" " embryonic stage | blastoderm , embryonic stage | stage 11 , embryonic stage | stage 17 , embryonic stage | stage 7 , embryonic stage | stage 9 , embryonic stage , embryonic stage | stage 7-13 , embryonic stage | stage 5 , embryonic stage | stage 5,6 " " stomodeum

, embryonic/larval pharynx | posterior

, intercalary segment

, mesoderm | posterior | restricted

, embryonic central nervous system

, embryonic/larval foregut

, labral segment

,

posterior | restricted , mesoderm | segmentally repeated

,

anterior | restricted " " embryonic stage | stage 5,6 , embryonic stage | stage 11 , embryonic stage | stage 9 , embryonic stage | stage 17 , embryonic stage | stage 7 , embryonic stage | stage 5 , embryonic stage | stage 7-13 " "

anterior | restricted , mesoderm | segmentally repeated

, mesoderm | posterior | restricted

, embryonic/larval pharynx | posterior

, stomodeum

, labral segment

, intercalary segment

,

posterior | restricted , embryonic/larval foregut

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,visible" "embryonic labral segment,embryonic antennal segment,embryonic intercalary segment,embryonic/larval esophagus,stomatogastric nervous system,embryonic/larval labral nerve,adult labral sense organ,dorsopharyngeal organ,pharyngeal monoscolopidial chordotonal organ,trichogen cell" FBgn0028554 x16 x16 splicing factor http://flybase.org/reports/FBgn0028554 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 mRNA binding ; GO:0003729 | inferred from direct assay RNA binding ; GO:0003723 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with Trn-SR mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with HGNC:10785 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from physical interaction with CG7564, Rbp1, Doa regulation of transcriptional start site selection at RNA polymerase II promoter ; GO:0001178 | inferred from mutant phenotype regulation of mRNA 3'-end processing ; GO:0031440 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "9G8, TN166, d9G8, Dxl6, CG10203, X16/9G8, Xl6, RBP1-like, l(2)k00230, 2/30, anon-WO0118547.78, dxl6, xl6, x16, XL6, dx16, Dx16, X16" "IPR000504:RNA recognition motif domain, IPR001878:Zinc finger, CCHC-type" CG10203 11-Aug-17 DroID_v2017_08 "Drer\srsf3b, Drer\srsf7a, Drer\srsf7b, Drer\srsf3a" "Scer\NAB3, Scer\NPL3" "Cele\rsp-6, Cele\Y57G11A.5" "Xtro\srsf3, Xtro\srsf7" "Mmus\Srsf7, Mmus\Srsf3" "Hsap\SRSF3, Hsap\HNRNPC, Hsap\SRSF7" " embryonic stage | stage 11 , embryonic stage | stage 5-11 , larval stage | third instar , embryonic stage | stage 14-16 , adult stage && oogenesis stage " " ventral neurogenic region

,

ubiquitous , eye-antennal disc | restricted

, ventral thoracic disc | restricted

, embryonic brain

, dorsal mesothoracic disc | restricted

, nurse cell

, embryonic central nervous system

" "visible,lethal,recessive,viable,fertile" "eye,trichogen cell" FBgn0025525 bab2 bric a brac 2 http://flybase.org/reports/FBgn0025525 "FBgn0012044, FBgn0035185" protein_coding_gene "AT DNA binding ; GO:0003680 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with bip2" "regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype female gonad morphogenesis ; GO:0061040 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 leg disc morphogenesis ; GO:0007478 | inferred from expression pattern eye-antennal disc morphogenesis ; GO:0007455 | inferred from expression pattern" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement polytene chromosome chromocenter ; GO:0005701 | NOT inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "bab, bab-II, BAB2, BTB-II, CG13911, CG9102, BtbII, bab2, Bab2, BAB" "IPR000210:BTB/POZ domain, IPR007889:DNA binding HTH domain, Psq-type, IPR011333:SKP1/BTB/POZ domain, IPR009057:Homeobox domain-like" CG9102 11-Aug-17 DroID_v2017_08 - - "Cele\sdz-28, Cele\btb-13" - "Mmus\Nacc2, Mmus\Nacc1" "Hsap\NACC2, Hsap\NACC1, Hsap\ZBTB12" " prepupal stage , larval stage | third instar " " ovary | restricted

, ventral thoracic disc | restricted

" " prepupal stage | stage P1 , prepupal stage , larval stage | third instar stage 2 , larval stage | third instar " " ovary | restricted

, central nervous system | restricted

, larval central nervous system | restricted

, ventral thoracic disc | restricted

, female genital disc | restricted

, male genital disc | restricted

" "visible,dominant,male,body color defective,recessive,female,female sterile,female fertile,partially lethal - majority die,lethal,viable,cell number defective,cell migration defective" "adult cuticle & abdominal segment 5 | male,adult cuticle & abdominal segment 6 | male,leg,ovary,abdominal tergite 5,female,abdominal tergite 6,ovariole,antenna,prothoracic tarsal segment 2,tarsal segment 4,tarsal segment 5,abdominal tergite 7,terminal filament,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 6,tergite,adult abdomen & cuticlep339,tarsal segment,wing,adult abdomen & cuticle30A,basal cylinder,arista,ectopic,haltere,wing hinge,wing disc,adult cuticle & abdominal segment | malepnr-MD237,abdominal sternite 6,male,abdominal sternite 7,abdominal sternite 6 & trichome | maleC-765,abdominal tergite 6 & trichome | maleC-765,abdominal sternite 6 & macrochaeta | maleC-765,abdominal tergite 6 & macrochaeta | maleC-765,mesothoracic tergum,terminal filament | prepupal stage,embryonic/larval dorsal vessel" FBgn0029082 hbs hibris http://flybase.org/reports/FBgn0029082 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with sns positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from genetic interaction with sns compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from genetic interaction with rst heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from direct assay regulation of striated muscle tissue development ; GO:0016202 | inferred from mutant phenotype inferred from genetic interaction with sns myoblast fusion ; GO:0007520 | traceable author statement establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype regulation of striated muscle tissue development ; GO:0016202 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype positive regulation of endopeptidase activity ; GO:0010950 | inferred from mutant phenotype Malpighian tubule stellate cell differentiation ; GO:0061330 | inferred from expression pattern inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay endosome ; GO:0005768 | colocalizes_with inferred from direct assay cell-cell adherens junction ; GO:0005913 | inferred from direct assay gamma-secretase complex ; GO:0070765 | colocalizes_with inferred from physical interaction with Psn "Hbs, CT22841, icon, CG7449, hbs" "IPR003006:Immunoglobulin/major histocompatibility complex, conserved site, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG7449 11-Aug-17 DroID_v2017_08 "Drer\mybpc2a, Drer\mybpc2b, Drer\nphs1, Drer\myom1a" - "Cele\him-4, Cele\syg-2" "Xtro\LOC100216153, Xtro\nphs1, Xtro\LOC100145501, Xtro\hepacam2" "Mmus\Igfn1, Mmus\Sirpb1a, Mmus\Mybpc1, Mmus\Sirpa, Mmus\Mybpc2, Mmus\Myom3, Mmus\Myom2, Mmus\Nphs1, Mmus\Mybpc3" "Hsap\CD33, Hsap\MYBPC2, Hsap\HMCN2, Hsap\MYBPC3, Hsap\IGFN1, Hsap\NPHS1, Hsap\MYBPC1, Hsap\MYOM2, Hsap\IGSF22, Hsap\SIRPG, Hsap\MYOM3, Hsap\PRODH2" embryonic stage | stage 15 embryonic Malpighian tubule | restricted

"visible,recessive,planar polarity defective,viable,fertile,cell adhesion defective,somatic clone,partially lethal - majority die,some die during pupal stage" "eye,cone cell,microchaeta & adult thorax,interommatidial bristle,supernumerary,somatic clone,photoreceptor cell R3,photoreceptor cell R7,ommatidium,wing margin,notal microchaeta,adult Malpighian tubule Type II cell,presumptive embryonic/larval muscle system,embryonic myoblast,midgut chamber 1,visceral muscle primordium,visceral mesoderm,somatic mesoderm,myoblast,distal,microchaeta & scutumda.G32,microchaeta & scutum-537.4,dorsal,microchaeta & scutumpnr-MD237,inter-ommatidial cell,inter-ommatidial precursor cell,primary pigment cell,septate junction | somatic clone,cell-cell junction | somatic clone,eye photoreceptor cell,inter-ommatidial precursor cell | pupal stage P6,interommatidial bristle | pupal stage P6,wing hair" FBgn0003862 trx trithorax http://flybase.org/reports/FBgn0003862 "FBgn0011040, FBgn0011340, FBgn0011443" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR001841, InterPro:IPR001965, InterPro:IPR016569 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | traceable author statement histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q94545 zinc ion binding ; GO:0008270 | inferred from sequence model chromatin binding ; GO:0003682 | inferred from direct assay protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCH5 protein homodimerization activity ; GO:0042803 | inferred from direct assay" histone H3 acetylation ; GO:0043966 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok histone acetylation ; GO:0016573 | inferred from direct assay histone H3-K4 methylation ; GO:0051568 | inferred by curator from GO:0044665 histone H3-K4 methylation ; GO:0051568 | inferred from direct assay eye development ; GO:0001654 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q9VCH5 axon guidance ; GO:0007411 | inferred from mutant phenotype histone methylation ; GO:0016571 | traceable author statement haltere development ; GO:0007482 | inferred from genetic interaction with UniProtKB:Q9VCH5 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype histone methylation ; GO:0016571 | inferred from direct assay germ cell migration ; GO:0008354 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from physical interaction with Sbf MLL1/2 complex ; GO:0044665 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from direct assay histone methyltransferase complex ; GO:0035097 | inferred from direct assay "trx, TRX, Trx, CG8651, trx-g, l(3)j14A6, DMTRXIII, trxI and trxII, NR0A5, 4733, 4720, Rg-bx, l(3)s5452, l(3)j3A2, l(3)bx[v], R-bx, Trx-G, tqrx, Trx/MLL, TrX" "IPR001214:SET domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001965:Zinc finger, PHD-type, IPR003616:Post-SET domain, IPR003888:FY-rich, N-terminal, IPR003889:FY-rich, C-terminal, IPR001841:Zinc finger, RING-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR016569:Methyltransferase, trithorax, IPR019787:Zinc finger, PHD-finger, IPR034732:Extended PHD (ePHD) domain, IPR001487:Bromodomain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8651 11-Aug-17 DroID_v2017_08 "Drer\si:ch211-57f7.7, Drer\kmt2ba, Drer\kmt2bb, Drer\si:ch211-37e10.1, Drer\phf11, Drer\kmt2a, Drer\setbp1" Scer\SET1 "Cele\set-25, Cele\lin-59" "Xtro\kmt2a, Xtro\LOC733724, Xtro\kmt2b" "Mmus\Phf11c, Mmus\Phf11d, Mmus\Phf7, Mmus\Setbp1, Mmus\Gm6904, Mmus\Kmt2b, Mmus\Phf11b, Mmus\Phf11a, Mmus\Kmt2a" "Hsap\SETBP1, Hsap\KMT2B, Hsap\PHF7, Hsap\PHF11, Hsap\KMT2A" " embryonic stage | early , embryonic stage , embryonic stage && larval stage && pupal stage , larval stage | third instar , adult stage | female , embryonic stage | stage 7-9 , embryonic stage | 11-15 hr , adult stage | male , embryonic stage | stage 5 , embryonic stage | 2-4hr , embryonic stage | stage 4 , embryonic stage -- adult stage , pupal stage , embryonic stage | late , embryonic stage | stage 4-8 " " embryonic central nervous system

, dorsal mesothoracic disc | posterior

,

ubiquitous , head

, imaginal disc

, dorsal metathoracic disc | posterior

, mesoderm | presumptive

, mesoderm anlage

, supraesophageal ganglion

, eye-antennal disc

, ventral mesothoracic disc | posterior

,

pair rule , subesophageal ganglion

, antenno-maxillary complex

, ventral nerve cord

,

20-50% egg length , ventral nervous system

, labral segment

, organism | even pair rule

" " larval stage | third instar , embryonic stage , larval stage " " dorsal mesothoracic disc | posterior

, dorsal metathoracic disc | posterior

, embryonic/larval proventriculus

, embryonic/larval salivary gland

, eye-antennal disc

, embryonic/larval midgut

, embryonic/larval digestive system

, ventral mesothoracic disc | posterior

, Malpighian tubule

, embryonic central nervous system

, imaginal disc

, gastric caecum

, larval fat body | central & posterior

" "viable,fertile,lethal,recessive,partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage,increased cell death,heat sensitive,wild-type,dominant,homeotic,lethal - all die before end of embryonic stage,some die during embryonic stage,non-suppressor of variegation,non-enhancer of variegation,enhancer of variegation,increased cell number,somatic clone,mitotic cell cycle defective,male,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,some die during immature adult stage" "adult thorax,wing disc | third instar larval stage,prothoracic tibia,sex comb,prothoracic segment,haltere,metathoracic segment,metathoracic tibia,abdominal tergite 5,male,abdominal tergite 6,abdominal tergite 7,wing,eye,head,labellum,lateral,photoreceptor cell,somatic clone,eye disc,abdominal segment 6,wing vein,ectopic,embryonic/first instar larval cuticle,embryonic/larval brain,embryonic/larval midgut,abdominal segment 5,adult abdominal segment 5,adult abdominal segment 6,adult abdominal segment 7,midgut constriction 1,midgut constriction 2,denticle belt,metathoracic laterotergite,abdominal tergite 2,abdominal tergite 3,antenna,maxillary palpus,adult head,arista,anterior,ventral,ocellar bristle,ocellus,postvertical bristle,pupal cuticle & abdomen,abdominal tergite 1,epiproct,adult,abdominal tergite 4,male genitalia,sternite,spiracle,abdominal segment,gonad,precursor,adult abdominal segment 4,epidermis,embryonic/larval tracheal system,mesothoracic tergum" FBgn0003430 slp1 sloppy paired 1 http://flybase.org/reports/FBgn0003430 FBgn0010610 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay" "regulation of gene expression ; GO:0010468 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement mesoderm formation ; GO:0001707 | traceable author statement blastoderm segmentation ; GO:0007350 | traceable author statement specification of segmental identity, head ; GO:0007380 | inferred from expression pattern inferred from mutant phenotype inferred from genetic interaction with bcd inferred from genetic interaction with ems inferred from genetic interaction with Kr inferred from genetic interaction with Raf inferred from genetic interaction with rl inferred from genetic interaction with tor inferred from genetic interaction with tsl inferred from genetic interaction with dl heart formation ; GO:0060914 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "slp, Slp, Slp1, CG16738, Dmslp1, Slp-1, slp-2, slp-1, FD6, l(2)05965, slp1, FoxG, SLP, sko1, SLP1" "IPR018122:Fork head domain conserved site1, IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG16738 11-Aug-17 DroID_v2017_08 "Drer\foxq2, Drer\foxk2, Drer\foxd2, Drer\foxd3, Drer\foxg1b, Drer\foxk1, Drer\foxg1a, Drer\foxg1c, Drer\foxb2, Drer\foxj1a, Drer\foxl1, Drer\foxb1b, Drer\foxb1a, Drer\foxg1d, Drer\si:ch211-262e15.1" "Scer\FHL1, Scer\HCM1, Scer\FKH2, Scer\FKH1" "Cele\fkh-9, Cele\pes-1, Cele\lin-31, Cele\fkh-2, Cele\fkh-10, Cele\unc-130" "Xtro\foxd4l1.1, Xtro\foxi4.2, Xtro\foxe3, Xtro\foxj1.2, Xtro\foxd3, Xtro\foxk2, Xtro\foxe1, Xtro\foxb1, Xtro\foxd2, Xtro\foxj1" "Mmus\Foxb1, Mmus\Foxg1, Mmus\Foxk1, Mmus\Foxb2, Mmus\Foxj1, Mmus\Foxl1, Mmus\Foxd3, Mmus\Foxk2" "Hsap\FOXG1, Hsap\FOXL1, Hsap\FOXB2, Hsap\FOXK1, Hsap\FOXJ1, Hsap\FOXB1, Hsap\FOXK2, Hsap\FOXD4, Hsap\FOXD3" " embryonic stage , embryonic stage | stage >7 , embryonic stage | stage 4 , embryonic stage | stage 4 | late , embryonic stage | stage 6 , embryonic stage | stage >=13 , embryonic stage | stage 5 " "

segment polarity , mandibular segment

,

70-100% egg length , organism | pair rule

, intercalary segment

,

71-87% egg length & ventral , labral segment

, embryonic/larval proventriculus

, ventral nerve cord

, embryonic procephalic segment | lateral

,

70-81% egg length & dorsal , organism | even pair rule

, organism | gap

" " embryonic stage | stage 8-11 , embryonic stage | stage 9-11 , embryonic stage | stage 5 , embryonic stage | stage 6,7 " " procephalic neurogenic region && embryonic antennal segment | restricted

, deuterocerebral neuroblast | subset

, procephalic neurogenic region &&of embryonic ocular segment | restricted

, organism | even pair rule

, procephalic neurogenic region && embryonic mandibular segment | restricted

, procephalic neurogenic region && labral segment | restricted

, tritocerebral neuroblast | subset

, protocerebral neuroblast | subset

, procephalic neurogenic region && intercalary segment | restricted

,

segment polarity " "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,segment polarity phenotype,cell migration defective,viable,visible,body color defective" "cuticle,denticle belt,lateral process,ventral arm of lacinia,hypostomal sclerite,embryonic/larval dorsal vessel,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,RP2 motor neuron,ectopic,RP2sib neuron,neuroblast NB4-2,neuroblast NB5-3,neuroblast NB3-5,neuroblast NB5-6,embryonic labial segment,embryonic/first instar larval cuticle & abdominal segment 1,embryonic/first instar larval cuticle & abdominal segment 3,embryonic/first instar larval cuticle & abdominal segment 5,embryonic/first instar larval cuticle & abdominal segment 7,embryonic/first instar larval cuticle & mesothoracic segment,head,embryonic head,mandibular segment,labial segment,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,visceral mesoderm,longitudinal visceral muscle primordium | embryonic stage 12,trichogen cell,mesothoracic tergum" FBgn0010433 ato atonal http://flybase.org/reports/FBgn0010433 - protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | contributes_to inferred from physical interaction with da" "oenocyte development ; GO:0007438 | inferred from mutant phenotype neuron recognition ; GO:0008038 | inferred from mutant phenotype R8 cell fate specification ; GO:0045464 | traceable author statement sensory perception of sound ; GO:0007605 | inferred from mutant phenotype antennal joint morphogenesis ; GO:0048801 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | inferred from mutant phenotype R8 cell differentiation ; GO:0045465 | traceable author statement sensory organ precursor cell fate determination ; GO:0016360 | traceable author statement second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | traceable author statement sensory organ development ; GO:0007423 | traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from direct assay optic lobe placode development ; GO:0001748 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from expression pattern eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | traceable author statement R8 cell fate commitment ; GO:0007460 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype activation of MAPK activity ; GO:0000187 | traceable author statement Bolwig's organ morphogenesis ; GO:0001746 | inferred from expression pattern R8 cell fate specification ; GO:0045464 | non-traceable author statement sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with Egfr smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with hh sensory organ development ; GO:0007423 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement nervous system development ; GO:0007399 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "ATO, ato1, CG7508, ato, At, Ato, bHLHa10, ato[Dm]" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR032664:Protein atonal/amos/lin-32" CG7508 11-Aug-17 DroID_v2017_08 "Drer\atoh7, Drer\neurod1, Drer\atoh1c, Drer\atoh1b, Drer\neurod6b, Drer\atoh1a, Drer\neurod4, Drer\neurod6a" - "Cele\cnd-1, Cele\lin-32" "Xtro\atoh7, Xtro\atoh1, Xtro\neurod6, Xtro\neurod4" "Mmus\Neurod1, Mmus\Neurod6, Mmus\Atoh7, Mmus\Neurod4, Mmus\Atoh1" "Hsap\ATOH1, Hsap\NEUROD6, Hsap\ATOH7, Hsap\NEUROD4, Hsap\NEUROD1" " embryonic stage | stage 13 , larval stage | third instar , embryonic stage , larval stage--pupal stage " " embryonic central brain | restricted

, larval protocerebrum

, C1 chordotonal organ precursor cell

, chordotonal organ

, external sensory organ

, eye-antennal disc

, prothoracic chordotonal organ

, chordotonal organ &&of wing

, chordotonal organ of tegula

, morphogenetic furrow

, mesothoracic femoral chordotonal organ

, ventral thoracic disc

, inner proliferation zone

, chordotonal organ of scabellum

, Johnston's organ

" " embryonic stage | stage 9-11 , embryonic stage | stage 13 , adult stage , embryonic stage | stage 8-10 " " deuterocerebral neuroblast | subset

, embryonic ganglion mother cell

, protocerebral neuroblast | subset

, adult brain | restricted

, procephalic neurogenic region &&of embryonic antennal segment | restricted

, procephalic neurogenic region &&of embryonic ocular segment | restricted

, embryonic central brain | restricted

" "neuroanatomy defective,thermotaxis behavior defective,wild-type,recessive,somatic clone,touch sensitivity defective,visible,locomotor behavior defective,song defective,auditory perception defective,neurophysiology defective,partially lethal - majority die,visual behavior defective,behavior defective,uncoordinated,lethal - all die before end of P-stage,some die during pharate adult stage,viable" "eye,neurite,dendrite | adult stage,T neuron T4,T neuron T5,chordotonal organ of wing,supernumerary,ommatidium,photoreceptor cell R8,heat sensitive,photoreceptor cell,somatic clone,antennal segment 3 & fasciclep13),neuron of aristal sensillum,antennal lobe glomerulus,glial cell,antenna,antennal lobe,glial cell & antennap13),sensillum coeloconicum of antennal segment 3,glial cell & antennal lobep13),interneuron & antennal lobep13),pioneer neuron & adult antennal nerve & pupap13),abdominal lateral pentascolopidial chordotonal organ lch5,embryonic/larval oenocyte,sacculus,embryonic/larval oenocyte precursor,oenocyte primordium,C1 chordotonal organ precursor cell,third segment of antenna,Johnston organ,eye photoreceptor cell,eye photoreceptor cell & axon,morphogenetic furrow & filopodium | somatic clone,eye disc,sensillum coeloconicum,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,maxillary palp sensillum basiconicum,basiconic sensillum of sacculus,adult antennal nerve,chordotonal organ,scolopidial neuron,eye-antennal disc,morphogenetic furrow,embryonic/larval brain,adult brain,wing,cholinergic neuron,antenna & neuron,Bolwig organ,sensory mother cell,sensory mother cell & antennal disc,ocellus,interommatidial bristle,optic lobe,ommatidial precursor cluster,embryonic antennal sense organ,olfactory neuron & embryonic antennal sense organ,lch5 neuron,chordotonal organ precursor cell & ventral thoracic disc,mitotic cell cycle & eye disc | somatic clone,external sensory organ,ectopic,macrochaeta,photoreceptor cell R7,scutellar bristle,wing vein L3,scutum,adult thorax & macrochaeta109,abdominal sternite bristle,wing sensillum,campaniform sensillum of anterior crossvein,sensory mother cell & dorsal mesothoracic disc109,sensory mother cell & dorsal mesothoracic discptc-559.1,adult head,sensillum basiconicum,sensillum trichodeum,sensillum basiconicum of antennal segment 3,lobula,medulla,optic chiasma,abdominal basiconical sensillum dbd & larva & nerve terminal.PC,multidendritic neuron,macrochaeta & wing | ectopicdpp.blk1,chordotonal organ & wing | ectopicdpp.blk1,sternopleural bristle" FBgn0004170 sc scute http://flybase.org/reports/FBgn0004170 "FBgn0003324, FBgn0003412, FBgn0026842" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with da protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da protein binding ; GO:0005515 | inferred from physical interaction with Bap60 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with l(1)sc sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from physical interaction with da sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from physical interaction with da transcription factor binding ; GO:0008134 | inferred from genetic interaction with E(spl)m7-HLH inferred from genetic interaction with E(spl)mγ-HLH" "nervous system development ; GO:0007399 | traceable author statement chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype central nervous system development ; GO:0007417 | traceable author statement sex determination ; GO:0007530 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype sex determination, establishment of X:A ratio ; GO:0007540 | non-traceable author statement negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype sex determination ; GO:0007530 | traceable author statement chaeta development ; GO:0022416 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with l(1)sc regulation of mitotic cell cycle ; GO:0007346 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement sex determination ; GO:0007530 | inferred from genetic interaction with Sxl ventral cord development ; GO:0007419 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement regulation of neurogenesis ; GO:0050767 | inferred from biological aspect of ancestor with PANTHER:PTN000358354 sensory organ development ; GO:0007423 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from genetic interaction with sisA sex determination ; GO:0007530 | inferred from genetic interaction with dpn inferred from genetic interaction with dpn, Sxl chaeta morphogenesis ; GO:0008407 | non-traceable author statement peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype" transcription factor complex ; GO:0005667 | inferred from physical interaction with da RNA polymerase II transcription factor complex ; GO:0090575 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 "sc, sis-b, sisB, Sc, EG:198A6.1, CG3827, scalpha, DROACS2, T4, T4 AS-C, scute/sisterlessB, sis b, sisb, AS-C T4sc, Hw, AS-C T4, ascT4, sc/T4, l(1)1Ba, bHLHc28, SC_DA" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR015660:Achaete-scute transcription factor-related" CG3827 11-Aug-17 DroID_v2017_08 "Drer\nhlh2, Drer\tcf23, Drer\tal2, Drer\msc, Drer\mespab, Drer\tcf15, Drer\figla, Drer\mespba, Drer\scxa, Drer\lyl1, Drer\msgn1, Drer\tal1, Drer\ptf1a, Drer\tcf21, Drer\hand2, Drer\ascl1b, Drer\ascl1a, Drer\scxb, Drer\mespaa, Drer\si:ch211-246m6.4, Drer\tcf24" - "Cele\hlh-3, Cele\hlh-14" "Xtro\ptf1a, Xtro\tcf15, Xtro\ascl3, Xtro\hand2, Xtro\msgn1, Xtro\mespb, Xtro\figla, Xtro\hand1, Xtro\lyl1, Xtro\tcf21, Xtro\scx, Xtro\mespa, Xtro\nhlh1, Xtro\msc, Xtro\tal1, Xtro\ascl2" "Mmus\Hand1, Mmus\Tcf15, Mmus\Nhlh2, Mmus\Ascl4, Mmus\Ascl1, Mmus\Ascl5, Mmus\Msc, Mmus\Figla, Mmus\Ferd3l, Mmus\Mesp2, Mmus\Ascl2, Mmus\Lyl1, Mmus\Nhlh1, Mmus\Tal1, Mmus\Msgn1, Mmus\Tal2, Mmus\Ptf1a, Mmus\Tcf23, Mmus\Hand2, Mmus\Tcf21, Mmus\Ascl3, Mmus\Mesp1, Mmus\Scx" "Hsap\TCF24, Hsap\TCF21, Hsap\ASCL4, Hsap\MESP1, Hsap\ASCL2, Hsap\MESP2, Hsap\MSGN1, Hsap\HAND2, Hsap\NHLH1, Hsap\ASCL3, Hsap\FIGLA, Hsap\ASCL1, Hsap\MSC, Hsap\HAND1, Hsap\TAL1, Hsap\NHLH2, Hsap\PTF1A, Hsap\TAL2, Hsap\TCF23, Hsap\SCX, Hsap\TCF15, Hsap\LYL1, Hsap\ASCL5" " embryonic stage ,, larval stage | third instar , larval stage | third instar stage 2 , pupal stage , embryonic stage | cycle 9-13 , embryonic stage | 0-12hr " " labral segment

, neuroblast

, stomodeum

, proneural cluster

, dorsal mesothoracic disc | restricted

, neurogenic region

, ectoderm

, dorsal mesothoracic disc

, embryonic peripheral nervous system

, sensory mother cell

, posterior embryonic/larval midgut

, central nervous system

, adult trachea | precursor

, cleavage nucleus

, ventral midline

, cephalic furrow

, sensory organ cell

, procephalic neuroblast

, procephalic segment

" " embryonic stage , larval stage , larval stage | third instar , embryonic stage | stage 10-11 , embryonic stage | stage 9-11 , embryonic stage | stage 12-14 , embryonic stage -- adult stage " " embryonic/larval hindgut | restricted

, embryonic peripheral nervous system | restricted

, proneural cluster

, dorsal mesothoracic disc | restricted

, sensory mother cell

, embryonic central nervous system

, ectoderm

, procephalic neuroblast | subset

, protocerebral neuroblast | subset

, embryonic stomatogastric nervous system

, neuroblast

, ventral neurogenic region

, wing vein L1

, C1 chordotonal organ precursor cell

, dorsal mesothoracic disc

, procephalic neurogenic region | restricted

, deuterocerebral neuroblast | subset

" "viable,male,reduced,fertile,visible,male sterile,recessive,female sterile,female,lethal,wild-type,male fertile,female fertile,partially lethal - majority die,heat sensitive,sex-determination defective,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,female limited,partially lethal - majority live,mitotic cell cycle defective,sterile,lethal - all die before end of P-stage,some die during pharate adult stage,flightless" "humeral bristle,postvertical bristle,ocellar bristle,scutellar bristle,anterior orbital bristle,anterior notopleural bristle,presutural bristle,anterior postalar bristle,anterior supraalar bristle,posterior postalar bristle,macrochaeta,ectopic,mesothoracic tergum,wing,mesothoracic tarsal bristle,mesothoracic tarsal bristle longitudinal row 6.5,mesothoracic tarsal bristle longitudinal row 6,anterior dorsocentral bristle,middle orbital bristle,heat sensitive,chaeta,tergite,notal microchaeta,supernumerary,prothoracic leg sensillum,mesothoracic leg sensillum,metathoracic leg sensillum,macrochaeta & leg,head,male,third segment of antenna,mesothoracic tergum & macrochaeta,posterior orbital bristle,posterior supraalar bristle,posterior notopleural bristle,dorsocentral bristle,proboscis & macrochaeta,upper humeral bristle,notopleural bristle,lower humeral bristle,orbital bristle,anterior vertical bristle,supraalar bristle,postalar bristle,sensillum campaniformium of dorsal radius Sc4d,vertical bristle,abdomen,abdominal sternite bristle,sternopleural bristle,anepisternum,posterior vertical bristle,microchaeta,anterior scutellar bristle,mesothoracic tarsal bristle longitudinal row 5.5,mesothoracic tarsal bristle longitudinal row 5,head bristle,posterior dorsocentral bristle,mechanosensory chaeta,posterior scutellar bristle,sternite,wing disc,sensory mother cell,sense organ,dorsal row & glial cell,ventral row & glial cell,anterior notal wing process sensillum campaniformium & glial cell,sensillum campaniformium of anterior crossvein & glial cell,sensillum campaniformium of dorsal radius & glial cell,mesothoracic metatarsus,wing sensillum,dorsal row,ventral row,eo neuron,tormogen cell,medial triple row,adult thoracic sensillum,external sensory organ,wing & external sensory organhs.PB,wing vein L2,multidendritic neuron,scutellum & microchaeta109,wing vein L3,scutum,sensory mother cell & dorsal mesothoracic disc109,sensory mother cell & dorsal mesothoracic discptc-559.1,mesothoracic tergum & macrochaeta | ectopic-C253,haltere,wing & macrochaetadpp.blk1,haltere sensillum,haltere & macrochaetadpp.blk1,macrochaeta & scutellum455.2,adult thorax & microchaetaap-md544,adult thorax & macrochaetaap-md544,mesothoracic tergum & macrochaeta | ectopicap-md544,dorsal medial muscle,chaeta | ectopic & mesothoracic tergumC-765" FBgn0046680 anon-38B.8 anon-38B.8 http://flybase.org/reports/FBgn0046680 gene - - - "38B.8, anon-38B.8" - - 11-Aug-17 DroID_v2017_08 - - - - - - FBgn0001150 gt giant http://flybase.org/reports/FBgn0001150 - protein_coding_gene "protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from biological aspect of ancestor with PANTHER:PTN000945219 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay" "specification of segmental identity, labial segment ; GO:0007381 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | inferred from mutant phenotype zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | traceable author statement ring gland development ; GO:0035271 | inferred from mutant phenotype regulation of transcription involved in anterior/posterior axis specification ; GO:0044324 | inferred from mutant phenotype salivary gland development ; GO:0007431 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype posterior head segmentation ; GO:0035289 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from genetic interaction with tor negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | non-traceable author statement torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "gt, Giant, EG:BACH7M4.5, CG7952, GIAN_DROME, l(1)giant, l(1)3Aa, Gt, GT, DM17" "IPR004827:Basic-leucine zipper domain, IPR029859:Protein giant, IPR015943:WD40/YVTN repeat-like-containing domain" CG7952 11-Aug-17 DroID_v2017_08 "Drer\dbpa, Drer\nfil3-5, Drer\cebp1, Drer\tefa, Drer\cebpb, Drer\si:dkey-172o19.2, Drer\tefb, Drer\dbpb, Drer\ddit3, Drer\hlfb, Drer\hlfa, Drer\nfil3-2, Drer\nfil3-4" - "Cele\zip-6, Cele\zip-7, Cele\atf-8, Cele\ces-2" "Xtro\hlf, Xtro\dbp, Xtro\cebpb" "Mmus\Tef, Mmus\Cebpe, Mmus\Cebpb, Mmus\Cebpa, Mmus\Hlf, Mmus\Dbp" "Hsap\DBP, Hsap\TEF, Hsap\HLF, Hsap\CEBPA" " embryonic stage | gastrulation , embryonic stage | extended germ band stage , embryonic stage | cellular blastoderm , embryonic stage | extended germ band , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | embryonic cycle 13 , embryonic stage | embryonic cycle 12,13 , embryonic stage | embryonic cycle 12 " "

anterior{ + kni* } , anterior embryonic/larval midgut

{ + Kr* } ,

20-25% egg length{ 0 kni* } , labral segment

,

33-45% egg length{ 0 Kr* } ,

90-100% egg length , organism | 60-70% egg length

, organism | 70-80% egg length

, organism | 20-30% egg length

,

anterior{ 0 eve* } ,

anterior{ + hb* } ,

14-20% egg length{ 0 hb* } , organism | 60-80% egg length

, cephalic furrow

, organism | 50-90% egg length

, organism | 0-30% egg length

, organism | 90-100% egg length

,

20-40% egg length " " embryonic stage , embryonic stage | stage 5 , embryonic stage | embryonic cycle 12 , embryonic stage | embryonic cycle 13 " " maxillary segment

, organism | 90-100% egg length

, labrum

, ring gland

, organism | 20-40% egg length

, mandibular segment

, organism | 0-30% egg length

, organism | 60-80% egg length

, organism | 10-20% egg length

, organism | 60-70% egg length

, organism | 70-80% egg length

" "lethal,recessive,visible,viable,body size defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,size defective" "larval salivary gland & embryo & nuclear chromosome,prothoracic gland innervating neuron PG-LP,prothoracic gland,nucleus | third instar larval stage,mesothoracic segment,metathoracic segment,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,embryonic/first instar larval cuticle,salivary gland,dorsal hair,ectopic,denticle belt,embryonic labial segment,embryonic prothoracic segment,dorsal ridge,abdominal 6 ventral denticle belt,hypostomal sclerite,embryonic abdominal segment,embryonic abdominal segment 6,embryonic abdominal segment 7,peripheral nervous system,chordotonal organ,lateral,larval abdominal segment 6,larval abdominal segment 7,embryonic stomatogastric nervous system,corpus cardiacum primordium,mouth hooks,hypophysis,embryonic/larval labial organ,larval head,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic head,embryonic abdominal segment 5,labial segment,thorax,anterior,abdominal segment 6,abdominal segment 7,larva" FBgn0004197 Ser Serrate http://flybase.org/reports/FBgn0004197 "FBgn0003111, FBgn0003355" protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 receptor binding ; GO:0005102 | non-traceable author statement Notch binding ; GO:0005112 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VUX2 Notch binding ; GO:0005112 | inferred from physical interaction with N Notch binding ; GO:0005112 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with mib1" "salivary gland development ; GO:0007431 | non-traceable author statement dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype lymph gland crystal cell differentiation ; GO:0035170 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype crystal cell differentiation ; GO:0042688 | traceable author statement negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | non-traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype glial cell proliferation ; GO:0014009 | inferred from mutant phenotype larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement negative regulation of Notch signaling pathway ; GO:0045746 | inferred from direct assay regulation of crystal cell differentiation ; GO:0042689 | traceable author statement larval lymph gland hemopoiesis ; GO:0035167 | inferred from expression pattern germ-line stem cell population maintenance ; GO:0030718 | inferred from genetic interaction with Dl eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | non-traceable author statement cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011651 axolemma ; GO:0030673 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "Ser, ser, CT18858, Bd, Rpw, std, mel(3)8, CG6127, SER" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001774:Delta/Serrate/lag-2 (DSL) protein, IPR001881:EGF-like calcium-binding domain, IPR011651:Notch ligand, N-terminal domain, IPR013032:EGF-like, conserved site, IPR009030:Growth factor receptor cysteine-rich domain, IPR026219:Jagged/Serrate protein, IPR001007:VWFC domain" CG6127 11-Aug-17 DroID_v2017_08 "Drer\jag1b, Drer\jag1a, Drer\adgrf6, Drer\sned1, Drer\fbln7, Drer\LOC100332841, Drer\col28a1a, Drer\jag2b, Drer\adgrl4, Drer\scube3, Drer\LOC562634, Drer\megf6b, Drer\scube1, Drer\svep1, Drer\crb2b, Drer\jag2a, Drer\zgc:158328, Drer\matn3a, Drer\fbln1, Drer\LOC100535882, Drer\si:ch73-173h19.3, Drer\crb2a, Drer\ltbp3, Drer\dlb, Drer\col28a1a, Drer\efemp1, Drer\dpy19l1l" - Cele\apx-1 "Xtro\col14a1, Xtro\fbn1, Xtro\ltbp4, Xtro\jag1, Xtro\crb2, Xtro\f12, Xtro\nell1, Xtro\svep1, Xtro\hgfac, Xtro\notch1, Xtro\matn4" "Mmus\Ltbp4, Mmus\Matn3, Mmus\Dll4, Mmus\Col22a1, Mmus\Egfl7, Mmus\Scube2, Mmus\Crb2, Mmus\Jag2, Mmus\Vwa1, Mmus\Col28a1, Mmus\Sned1, Mmus\Vwce, Mmus\Cfc1, Mmus\Hmcn2, Mmus\F12, Mmus\Jag1, Mmus\Tdgf1, Mmus\Dlk2, Mmus\Ltbp1, Mmus\Scube3, Mmus\Fbn1, Mmus\Dll3, Mmus\Habp2, Mmus\Svep1, Mmus\Dlk1, Mmus\Hgfac, Mmus\Fbln7, Mmus\Vwde" "Hsap\F12, Hsap\COL22A1, Hsap\SCUBE3, Hsap\HGFAC, Hsap\CFC1B, Hsap\DLK1, Hsap\DLL3, Hsap\VWCE, Hsap\EYS, Hsap\LOC100996717, Hsap\SNED1, Hsap\HABP2, Hsap\CRB2, Hsap\DLL4, Hsap\LTBP1, Hsap\SVEP1, Hsap\DLK2, Hsap\NOTCH2NL, Hsap\CFC1, Hsap\TDGF1, Hsap\SCUBE2, Hsap\FBLN7, Hsap\EGFL7, Hsap\VWA1, Hsap\COL14A1, Hsap\MATN3, Hsap\JAG2, Hsap\JAG1" " embryonic stage , adult stage | female , larval stage | third instar , embryonic stage | 2-4 hr , adult stage | male " " epidermis | stripes

, embryonic/larval foregut

, alula

, stomodeum

, embryonic/larval proventriculus

, embryonic/larval salivary gland

, trachea

, maxillary lobe

, mandibular segment

, embryonic salivary gland

, embryonic/larval hindgut

, embryonic/larval posterior spiracle

, central nervous system

, embryonic/larval hypopharynx

, supraesophageal ganglion

, labial segment

, labral segment

, embryonic/larval anterior spiracle

, embryonic/larval pharynx

, maxillary segment

, frontal head air sac | ventral

, dorsal mesothoracic disc

, anal pad

, epidermis

, telson

" " embryonic stage , larval stage | third instar " " embryonic/larval posterior spiracle

, stomodeum

, dorsal mesothoracic disc

, embryonic/larval pharynx

, embryonic/larval salivary gland

, supraesophageal ganglion

, mandibular segment

, epidermis

, frontal head air sac | ventral

, embryonic/larval foregut

, commissure

, labial segment

, alula

, embryonic/larval hindgut

, trachea

, embryonic/larval anterior spiracle

, labral segment

, epidermis | stripes

, maxillary segment

, anal pad

, embryonic/larval proventriculus

" "neuroanatomy defective,visible,viable,dominant,mitotic cell cycle defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal,cold sensitive,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,cell polarity defective,male fertile,size defective,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,body color defective" "interface glial cell,wing vein,wing margin,wing,distal,proneural cluster,optic lobe,glial cell,haltere,mesothoracic metatarsus,mesothoracic tarsal segment 2,metathoracic tarsal segment 2,prothoracic metatarsus,prothoracic tarsal segment 2,metathoracic metatarsus,crystal cell,embryonic head,mouth hooks,leg,tibia,femur,anterior,heat sensitive,eye,cold sensitive,adult heart,embryonic/larval anterior spiracle,papilla of larval anterior spiracle,wing disc,commissure,axon,dorsal closure embryo,denticle,cuticle,dorsal hair,dorsal compartment,somatic clone,joint,leg & joint,tarsal segment 1 & joint,tarsal segment 2 & joint,tarsal segment 3 & joint,tarsal segment 4 & joint,tarsal segment 5 & joint,denticle row 3 & abdominal 2 ventral denticle belt,denticle row 4 & abdominal 2 ventral denticle belt,denticle row 3 & abdominal 3 ventral denticle belt,denticle row 4 & abdominal 3 ventral denticle belt,denticle row 3 & abdominal 4 ventral denticle belt,denticle row 4 & abdominal 4 ventral denticle belt,denticle row 3 & abdominal 5 ventral denticle belt,denticle row 4 & abdominal 5 ventral denticle belt,denticle row 3 & abdominal 6 ventral denticle belt,denticle row 4 & abdominal 6 ventral denticle belt,denticle row 3 & abdominal 7 ventral denticle belt,denticle row 4 & abdominal 7 ventral denticle belt,denticle row 3 & abdominal 8 ventral denticle belt,denticle row 4 & abdominal 8 ventral denticle belt,dorsal pouch,dorsal bridge,lateral process,embryonic/larval proventriculus,embryonic/larval digestive system,hub cell,salivary gland imaginal ring,macrochaeta,ectopic,dorsal/ventral compartment boundary,actin filament & larval salivary gland,denticle row 3,denticle row 4,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 6,adult abdominal segment 7,procrystal cell,embryonic/larval salivary gland duct,presumptive embryonic/larval nervous system,embryonic epidermis,eye disc,dorsal,ventral,antenna,morphogenetic furrow,eye-antennal disc,supernumerary,medulla,ommatidium,interommatidial bristle,pigment cell,lens,eye photoreceptor cell,photoreceptor cell R7,ventral compartment,neuron,embryonic/larval proventriculus | embryonic stage,embryonic/larval digestive system | embryonic stage,presutural bristle & trichogen celll(3)31-1-31-1,anterior notopleural bristle & trichogen celll(3)31-1-31-1,posterior notopleural bristle & trichogen celll(3)31-1-31-1,anterior supraalar bristle & trichogen celll(3)31-1-31-1,posterior supraalar bristle & trichogen celll(3)31-1-31-1,anterior postalar bristle & trichogen celll(3)31-1-31-1,posterior postalar bristle & trichogen celll(3)31-1-31-1,anterior dorsocentral bristle & trichogen celll(3)31-1-31-1,posterior dorsocentral bristle & trichogen celll(3)31-1-31-1,anterior scutellar bristle & trichogen celll(3)31-1-31-1,microchaeta,scutum & macrochaeta & trichogen celll(3)31-1-31-1,tarsal segment,wing & macrochaetadpp.blk1,wing sensillum,macrochaeta & wingptc-559.1,dorsal row,ventral row,wing margin bristle,wing & macrochaeta | dorsalBx-MS1096,scutum & macrochaetaBx-MS1096,scutum,macrochaeta & wingh-540.3,tarsal segment 4,embryonic/larval lymph gland | larval stage,embryonic/larval lymph gland,rhabdomere,eye photoreceptor cell & eye disc | posterior-537.4,macrochaeta & thorax | supernumerary-537.4,eye photoreceptor cell & eye disch-H10,macrochaeta & scutellum | supernumerary | somatic clone | cell autonomous-109-68,macrochaeta & thorax | supernumerary | somatic cloneUbx.PdC,macrochaeta & thorax | somatic cloneUbx.PdC,trichogen cell,mesothoracic tergum" FBgn0000014 abd-A abdominal A http://flybase.org/reports/FBgn0000014 - protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" "apoptotic process ; GO:0006915 | inferred from mutant phenotype gonad development ; GO:0008406 | traceable author statement oenocyte development ; GO:0007438 | inferred from mutant phenotype dorsal vessel heart proper cell fate commitment ; GO:0035053 | traceable author statement mesodermal cell fate specification ; GO:0007501 | inferred from mutant phenotype muscle cell fate specification ; GO:0042694 | inferred from mutant phenotype genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype pole cell migration ; GO:0007280 | traceable author statement neuroblast development ; GO:0014019 | inferred from mutant phenotype midgut development ; GO:0007494 | traceable author statement dorsal vessel heart proper cell fate commitment ; GO:0035053 | inferred from mutant phenotype anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype genitalia development ; GO:0048806 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement germ cell migration ; GO:0008354 | inferred from mutant phenotype dorsal vessel heart proper cell fate commitment ; GO:0035053 | inferred from expression pattern inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement positive regulation of muscle organ development ; GO:0048636 | inferred from mutant phenotype cardioblast differentiation ; GO:0010002 | inferred from mutant phenotype gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype cardiac muscle tissue development ; GO:0048738 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with exd inferred from physical interaction with hth "abd-A, abdA, Abd-A, iab-4, AbdA, iab-2, Cbxd, Abda, CG10325, iab-3, DmabdA, iab4, abda, Hab, abd A, iab3, iab2, abd-a, iab-5, l(3)89Ec, iab, BX-C, ABD-A, abd_a, Dmabda, Fab-3, Fab-4" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa, IPR015943:WD40/YVTN repeat-like-containing domain, IPR022132:Homeobox protein" CG10325 11-Aug-17 DroID_v2017_08 "Drer\hoxa3a, Drer\hoxb5b, Drer\hoxb6b, Drer\hoxc3a, Drer\hoxc8a, Drer\hoxb7a, Drer\hoxc4a, Drer\hoxb5a, Drer\mnx1, Drer\hoxa9b, Drer\meox2b, Drer\pdx1, Drer\meox1, Drer\hoxb1b, Drer\hoxb8b, Drer\hoxb8a, Drer\gsx2, Drer\hoxc6b, Drer\hoxb1a, Drer\meox2a, Drer\hoxc1a, Drer\gbx2, Drer\hoxb3a, Drer\gbx1, Drer\gsx1, Drer\hoxb2a, Drer\hoxd3a, Drer\hoxa4a, Drer\hoxa1a, Drer\hoxb6a, Drer\mnx2a, Drer\hoxd4a, Drer\hoxc5a, Drer\hoxa5a, Drer\hoxb4a, Drer\hoxa2b, Drer\hoxc6a" "Scer\YHP1, Scer\YOX1, Scer\PHO2" "Cele\lin-39, Cele\mab-5" "Xtro\pdx1, Xtro\hoxb2, Xtro\hoxb3, Xtro\hoxa1, Xtro\gbx2.2, Xtro\hoxb5, Xtro\hoxb1, Xtro\hoxb4, Xtro\gsx1, Xtro\hoxa3, Xtro\hoxc8, Xtro\hoxa2, Xtro\meox2, Xtro\hoxa5, Xtro\hoxd1, Xtro\gbx2.1, Xtro\mnx1, Xtro\hoxc5, Xtro\hoxb8, Xtro\hoxd8, Xtro\hoxb6, Xtro\hoxc4, Xtro\gsx2, Xtro\hoxc3, Xtro\hoxb7, Xtro\hoxd3" "Mmus\Hoxb8, Mmus\Hoxb1, Mmus\Hoxc4, Mmus\Meox2, Mmus\Hoxc5, Mmus\Mnx1, Mmus\Hoxb9, Mmus\Gbx1, Mmus\Hoxb7, Mmus\Hoxa9, Mmus\Hoxc8, Mmus\Hoxc6, Mmus\Hoxd3, Mmus\Hoxb5, Mmus\Hoxd1, Mmus\Hoxa1, Mmus\En1, Mmus\Hoxd9, Mmus\Hoxc9, Mmus\Meox1, Mmus\Hoxa3, Mmus\Gbx2, Mmus\Pdx1, Mmus\Hoxa4, Mmus\Hoxd8, Mmus\Gsx1, Mmus\Hoxa2, Mmus\Hoxa7, Mmus\Hoxb3, Mmus\Hoxb6, Mmus\Hoxa6, Mmus\Hoxb4, Mmus\Hoxa5, Mmus\Hoxb2, Mmus\Hoxd4, Mmus\Gsx2" "Hsap\HOXD3, Hsap\HOXB3, Hsap\HOXD8, Hsap\HOXB7, Hsap\HOXD4, Hsap\HOXC8, Hsap\HOXA1, Hsap\GSX2, Hsap\HOXB8, Hsap\MEOX2, Hsap\HOXA6, Hsap\HOXA7, Hsap\HOXA5, Hsap\HOXC5, Hsap\HOXC6, Hsap\HOXA3, Hsap\MEOX1, Hsap\GSX1, Hsap\HOXD1, Hsap\HOXB1, Hsap\MNX1, Hsap\HOXB2, Hsap\HOXB6, Hsap\PDX1, Hsap\GBX2, Hsap\HOXB4, Hsap\HOXC4, Hsap\HOXB5, Hsap\GBX1, Hsap\HOXA4, Hsap\HOXA2" " embryonic stage , embryonic stage | stage 1-17 , embryonic stage | 2-4 hr , embryonic stage | stage 12 " parasegment 7--13

" embryonic stage | stage 15 , embryonic stage , embryonic stage | stage 12 , embryonic stage | stage 13-14 , larval stage , larval stage | third instar , embryonic stage | late , embryonic stage | stage 13 , embryonic stage | stage 16 , embryonic stage | stage 9-17 , embryonic stage | stage 10 , embryonic stage | stage 8 , embryonic stage | stage 7-12 " " pericardial cell

, ventral nerve cord

, neuroblast

, embryonic/larval trachea

, dorsal mesothoracic disc | retricted

, parasegment 13..15

{ + Abd-BM5 } , male genital disc | restricted

, epidermis

, embryonic dorsal vessel | posterior

, epidermis &&of gonad

, parasegment 14,15

, visceral mesoderm &&of parasegment 8--12

, amnioserosa

{ + Abd-BM1 } , ectoderm &&of parasegment 7--13

, gonad

, epidermis &&of ventral intersegmental neuron

, parasegment 14,15

{ + Abd-Biab9-tuh-3 } , visceral mesoderm &&of parasegment 8--12 &&of embryonic/larval midgut

, parasegment 7--13

, embryonic/larval spiracle

, chordotonal organ

, cardioblast && embryonic pericardial cell &&of embryonic abdominal segment 6--7

, embryonic heart

, parasegment 14,15

{ + Abd-B* } , abdominal 4--7 ventral intersegmental neuron

, visceral mesoderm

, female genital disc | restricted

, parasegment 7--13 , larval fat body | central

, parasegment 7--13

segmentally repeated , V neuron

, mesoderm &&of parasegment 8--12

, parasegment 7--13 &&of ventral nervous system

, cardioblast &&of embryonic abdominal segment 5,8

, alary cell | subset

, ventral nerve cord

segment A2-A7 , dorsal fibers of larval heart | lateral

, parasegment 13

{ + Abd-Biab9-x23-1 } , abdominal segment 1

, intersegmental nerve

, tracheal pit

, parasegment 7--12

" "homeotic,visible,dominant,viable,lethal - all die before end of P-stage,recessive,some die during pharate adult stage,locomotor rhythm defective,wild-type,lethal,increased cell death,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,heat sensitive,male sterile,female sterile,chemical sensitive,neuroanatomy defective" "abdominal segment,abdominal ventral denticle belt,embryonic/larval oenocyte precursor,lch5 neuron,embryonic thoracic segment,larval prothoracic segment,abdominal tergite 1,abdominal tergite 2,abdominal sternite 2,sternite,abdominal tergite 3,abdominal tergite 4,abdominal sternite 3,abdominal sternite 4,haltere,leg,wing,tergite,neuroblast,embryonic/larval somatic muscle,embryonic/larval tracheal system,,metathoracic segment,metathoracic leg,haltere disc,metathoracic leg disc,head,thorax,A-subperineurial glial cell,B-subperineurial glial cell of abdomen,mesothoracic segment,chordotonal organ,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,embryo,parasegment 7,parasegment 8,parasegment 9,parasegment 10,parasegment 11,parasegment 12,parasegment 13,embryonic/larval central nervous system,embryonic epidermis,Wheeler's organ,abdominal sternite 5,gonad,abdominal sternite 6,ovary,female genitalia,heart primordium,cardioblast,embryonic/larval ostia,pole cell,genital disc primordium,gonadal sheath proper primordium,embryonic/larval heart,embryonic/larval aorta,dorsal closure embryo,germline cell,fat body/gonad primordium,abd-Aiab3-Uab4,Keilin's organ,embryonic/larval midgut,abdominal lateral pentascolopidial chordotonal organ,cuprophilic cell,midgut interstitial cell,embryonic/larval oenocyte,oviduct,testis,epidermis,lch5 ligament attachment cell,midgut constriction,abd-AMX1,Df(3R)Ubx109,A1-7 ventral acute muscle 1,how-24B,A2-7 ventral oblique muscle 6,A2-7 ventral transverse muscle 1,aorta primordium,embryonic dorsal vessel,embryonic visceral muscle,dorsal acute muscle,embryonic mesothoracic segment,embryonic metathoracic segment,embryonic prothoracic segment,antenna,scutum,metathoracic laterotergite,NP5169,cephalopharyngeal skeleton,pharynx,embryonic/larval dorsal vessel,myofibril,cardiogenic mesoderm,metathoracic dorsal triscolopidial chordotonal organ dch3,embryonic tritocerebrum,embryonic/larval lymph gland,embryonic/larval pericardial cell,embryonic/larval posterior spiracle,abdominal 11 anal tuft,69B,wing margin,ppk.PG,EL neuron,arista,pretarsus,eye" FBgn0004595 pros prospero http://flybase.org/reports/FBgn0004595 "FBgn0010941, FBgn0011397, FBgn0011437, FBgn0011497, FBgn0011499, FBgn0011504, FBgn0011507, FBgn0011515, FBgn0011524, FBgn0020281, FBgn0024917, FBgn0026852, FBgn0044730, FBgn0063172" protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from mutant phenotype transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement inferred from mutant phenotype" "glial cell differentiation ; GO:0010001 |... mutant phenotype <> cell fate commitment ; GO:0045165 |... mutant phenotype <> dendrite morphogenesis ; GO:0048813 |... mutant phenotype <> axonogenesis ; GO:0007409 |... mutant phenotype <> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 |... biological aspect of ancestor with PANTHER:PTN000258074 <> eye photoreceptor cell differentiation ; GO:0001754 | traceable author statement <> peripheral nervous system development ; GO:0007422 | traceable author statement <> phagocytosis ; GO:0006909 |... mutant phenotype <> neuroblast fate determination ; GO:0007400 | traceable author statement <> regulation of R7 cell differentiation ; GO:0045676 |... mutant phenotype inferred from genetic interaction with sv <> compound eye cone cell fate commitment ; GO:0042676 | traceable author statement <> negative regulation of cell proliferation ; GO:0008285 |... mutant phenotype <> brain development ; GO:0007420 |... mutant phenotype <> regulation of protein localization to nucleus ; GO:1900180 |... mutant phenotype <> central nervous system development ; GO:0007417 |... mutant phenotype <> asymmetric neuroblast division resulting in ganglion mother cell formation ; GO:0055060 |... mutant phenotype <> dendrite guidance ; GO:0070983 |... mutant phenotype <> central nervous system development ; GO:0007417 | traceable author statement <> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 |... mutant phenotype <> synapse assembly ; GO:0007416 |... mutant phenotype <> negative regulation of gene expression ; GO:0010629 |... mutant phenotype <> R7 cell fate commitment ; GO:0007465 |... mutant phenotype <> axon guidance ; GO:0007411 |... mutant phenotype <> negative regulation of axonogenesis ; GO:0050771 |... mutant phenotype <> ganglion mother cell fate determination ; GO:0007402 | traceable author statement <> regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement <> G1 to G0 transition ; GO:0070314 |... mutant phenotype <> positive regulation of gene expression ; GO:0010628 |... mutant phenotype <> nervous system development ; GO:0007399 |... mutant phenotype <> male courtship behavior ; GO:0008049 |... mutant phenotype <> sensory organ development ; GO:0007423 | traceable author statement <> sensory perception of taste ; GO:0050909 |... mutant phenotype <> peripheral nervous system development ; GO:0007422 |... mutant phenotype <> courtship behavior ; GO:0007619 | traceable author statement <> neuroblast proliferation ; GO:0007405 |... mutant phenotype <> asymmetric cell division ; GO:0008356 | traceable author statement <> axonogenesis involved in innervation ; GO:0060385 |... mutant phenotype <> cell fate specification ; GO:0001708 | traceable author statement <> neuroblast fate determination ; GO:0007400 | non-traceable author statement <> ventral cord development ; GO:0007419 | traceable author statement <> protein localization ; GO:0008104 |... mutant phenotype <> regulation of neuron differentiation ; GO:0045664 |... mutant phenotype <> asymmetric neuroblast division ; GO:0055059 |... mutant phenotype <> R7 cell fate commitment ; GO:0007465 | traceable author statement <> regulation of retinal cone cell fate specification ; GO:0042673 |... mutant phenotype inferred from genetic interaction with sv <> nervous system development ; GO:0007399 | traceable author statement <> negative regulation of neuroblast proliferation ; GO:0007406 |... mutant phenotype" apical cortex ; GO:0045179 | inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement basal cortex ; GO:0045180 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay basal cortex ; GO:0045180 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement cell cortex ; GO:0005938 | inferred from direct assay basal part of cell ; GO:0045178 | non-traceable author statement basal part of cell ; GO:0045178 | traceable author statement cell cortex ; GO:0005938 | traceable author statement "Pros, Prosp, pro, Voila, DROPROSA, PROS-2, PROS-1, DMPROSPER, l(3)10419, 671/2, 1316/02, 1167/13, 1135/09, 1135/07, 0989/01, 0763/13, 0671/02, 0664/07, 0585/13, 0563/18, 0451/09, 0441/16, 0320/10, 0244/09, l(3)rO534, l(3)rL433, l(3)rK204, l(3)rK137, l(3)rJ806, l(3)rI160, l(3)rH013, l(3)j6E2, l(3)j12C8, CG17228, BcDNA:HL08040, anon-WO0140519.15, pros, PROS, Pro, voila, Prospero" "IPR009057:Homeobox domain-like, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR023082:Homeo-prospero domain" CG17228 11-Aug-17 DroID_v2017_08 "Drer\prox1a, Drer\prox1b, Drer\prox2" - "Cele\set-9, Cele\pros-1" Xtro\prox1 "Mmus\Prox2, Mmus\Prox1" "Hsap\PROX1, Hsap\PROX2" " embryonic stage | stage 10 , embryonic stage , embryonic stage | 12-15 hr , embryonic stage | stage 6 , embryonic stage | stage 5-7 , embryonic stage | stage 9 , embryonic stage | blastoderm " " sensory mother cell

, glioblast

, embryonic peripheral nervous system

, neuroblast

, interface glial cell

, scolopidium

, ventral midline

, organism | pair rule

, thecogen cell &&of external sensory organ

, procephalic neurogenic region

, ganglion mother cell

, garland cell

, abdominal 1--7 lateral pentascolopidial chordotonal organ lch5

, scolopidial sheath cell

,

ubiquitous " " embryonic stage | stage 9 , embryonic stage , embryonic stage | stage 11 " " ganglion mother cell &&of procephalic neurogenic region

, thecogen cell &&of external sensory organ

, ganglion mother cell &&of ventral nerve cord

, neuroblast MP2

, glial cell

, embryonic neuron

, scolopidium

, ganglion mother cell

" "lethal,recessive,courtship behavior defective,male,mating defective,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,temperature conditional,small body,taste perception defective,developmental rate defective,locomotor behavior defective,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,lethal - all die before end of P-stage,some die during pharate adult stage,male sterile,some die during immature adult stage,somatic clone,viable,mitotic cell cycle defective,female fertile,visible,tumorigenic,decreased cell size,increased cell number" "embryonic/larval glial cell,anterior commissure,posterior commissure,longitudinal connective,presumptive embryonic/larval central nervous system,presumptive embryonic/larval peripheral nervous system,axon,eye,axon & photoreceptor cell R7 | somatic clone,commissure,embryonic/larval neuromuscular junction,frontal ganglion,stomodeal nerve,esophageal ganglion 1,esophageal ganglion 2,photoreceptor cell R7,carbon dioxide sensitive neuron,ectopic,somatic clone,embryonic/larval brain,scutum & microchaeta,scutum & microchaeta & trichogen cell,scutum & microchaeta & tormogen cell,scutum & external sensory organ,peripheral nervous system,central nervous system,pCC neuron,aCC neuron,ventral midline,ventral nerve cord,RP2 motor neuron,U neuron,scutum & macrochaeta | somatic clone,interommatidial bristle,dendrite | dorsal | embryonic stage,dorsal,sensory neuron,peripheral glial cell,intersegmental nerve root glial cell,midline glial cell,filopodium & muscle cell,medial-most cell body glial cell,medial cell body glial cell,neuroblast NB6-4 of thorax,neuroblast NB7-4,trichogen cell,tormogen cell,scutum & macrochaeta,head bristle,head bristle & trichogen cell,head bristle & tormogen cell,head bristle & eo neuron,scutum & macrochaeta & eo neuron,scutum & microchaeta & eo neuron,interommatidial bristle & trichogen cell,interommatidial bristle & eo neuron,neuroblast,embryonic/larval neuroblast,ganglion mother cell,lens,adult olfactory receptor neuron Gr21a/63a,maxillary palp olfactory receptor neuron,embryonic ganglion mother cell,dendritic arborizing neuron,dendrite,chordotonal organ & axon | lateral,interface glial cell,neuron,motor neuron,hypodermal muscle of larval abdominal 4,hypodermal muscle of larval abdominal 5,cone cell,supernumerary,rhabdomere R7,primary pigment cell,scutum & external sensory organ & trichogen cell-P309,scutum & external sensory organ & tormogen cell-P309,antenna,microchaeta & antennal segment 3-P309,neuroblast NB7-3,morphogenetic furrow,scutum & macrochaeta-109-68,scutum & microchaeta-109-68,scutum & macrochaeta & trichogen cell-109-68,scutum & microchaeta & trichogen cell-109-68,interommatidial bristle & trichogen cell-109-68,scutum & macrochaeta & tormogen cell-109-68,scutum & microchaeta & tormogen cell-109-68,interommatidial bristle & tormogen cell-109-68,mesoderm,embryonic epidermis,neuroblast | larval stage,larval outer optic anlage,adult antennal lobe projection neuron DL1 adPN" FBgn0016797 fz2 frizzled 2 http://flybase.org/reports/FBgn0016797 - protein_coding_gene "Wnt-activated receptor activity ; GO:0042813 | inferred from direct assay PDZ domain binding ; GO:0030165 | inferred from physical interaction with Grip Wnt-protein binding ; GO:0017147 | inferred from direct assay Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt2, Wnt4, wg transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity Wnt-protein binding ; GO:0017147 | inferred from physical interaction with wg" female gonad development ; GO:0008585 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from physical interaction with Grip cell migration ; GO:0016477 | inferred from mutant phenotype receptor-mediated endocytosis ; GO:0006898 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from direct assay regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype retinal ganglion cell axon guidance ; GO:0031290 | inferred from mutant phenotype synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with fz signal transduction ; GO:0007165 | inferred from sequence or structural similarity axon guidance ; GO:0007411 | inferred from mutant phenotype regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype endocytic vesicle ; GO:0030139 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay late endosome ; GO:0005770 | colocalizes_with inferred from direct assay early endosome ; GO:0005769 | colocalizes_with inferred from direct assay "Dfz2, D-fz2, DFz2, Dfrz2, DFz-2, dfz(2), fz-2, dFz2, dfz2r, DFZ2, D-Fz2, CG9739, fz2, dfz2, Fz2, Dfz[[2]], FZ2, frz2, Dm Fz2, frizzled 2, DFz2C" "IPR017981:GPCR, family 2-like, IPR000539:Frizzled protein, IPR015526:Frizzled/secreted frizzled-related protein, IPR020067:Frizzled domain, IPR026554:Frizzled, invertebrates" CG9739 11-Aug-17 DroID_v2017_08 "Drer\fzd7a, Drer\sfrp1b, Drer\fzd3a, Drer\fzd8b, Drer\LOC101884738, Drer\fzd6, Drer\frzb, Drer\si:cabz01033205.3, Drer\fzd3b, Drer\sfrp5, Drer\fzd2, Drer\szl, Drer\corin, Drer\fzd4, Drer\smo, Drer\fzd10, Drer\fzd9a, Drer\sfrp2l, Drer\fzd7b, Drer\fzd8a, Drer\sfrp2, Drer\fzd5, Drer\fzd9b, Drer\sfrp1a, Drer\LOC103908663" - "Cele\mom-5, Cele\cfz-2, Cele\lin-17" "Xtro\sfrpx, Xtro\szl, Xtro\fzd10, Xtro\sfrp2, Xtro\sfrp5, Xtro\corin, Xtro\frzb2, Xtro\mfrp, Xtro\fzd3, Xtro\fzd4, Xtro\col18a1, Xtro\smo, Xtro\fzd9, Xtro\fzd5, Xtro\sfrp1, Xtro\fzd8, Xtro\frzb, Xtro\fzd2, Xtro\fzd6, Xtro\fzd7" "Mmus\Fzd2, Mmus\Fzd1, Mmus\Corin, Mmus\Sfrp2, Mmus\Smo, Mmus\Sfrp5, Mmus\Mfrp, Mmus\Fzd6, Mmus\Fzd5, Mmus\Sfrp1, Mmus\Fzd10, Mmus\Fzd9, Mmus\Fzd3, Mmus\Frzb, Mmus\Fzd7, Mmus\Fzd8, Mmus\Fzd4, Mmus\Sfrp4" "Hsap\FZD2, Hsap\FZD10, Hsap\FZD9, Hsap\FRZB, Hsap\CORIN, Hsap\FZD8, Hsap\FZD7, Hsap\FZD1, Hsap\FZD6, Hsap\FZD3, Hsap\SFRP4, Hsap\SMO, Hsap\SFRP1, Hsap\SFRP2, Hsap\SFRP5, Hsap\MFRP, Hsap\FZD4, Hsap\FZD5" " embryonic stage | stage 10 , embryonic stage | stage 9-17 , embryonic stage | stage 12-16 , embryonic stage | stage 8 , embryonic stage | stage 6 , embryonic stage | stage 13-17 , embryonic stage -- adult stage , embryonic stage | stage 17 " " procephalic neurogenic region

, embryonic central nervous system | presumptive

, visceral mesoderm

, posterior midgut proper primordium

,

segmentally repeated , organism | 10-70% egg length

, embryonic/larval hindgut

, embryonic/larval dorsal vessel

" " embryonic stage | stage 10 , embryonic stage | stage 12-16 , embryonic stage | stage 9-17 , embryonic stage | stage 17 , embryonic stage | stage 13-17 , larval stage | third instar " " posterior midgut proper primordium

, procephalic neurogenic region

, visceral mesoderm

, embryonic central nervous system | presumptive

, embryonic/larval dorsal vessel

, embryonic/larval hindgut

, bouton | subset

" "partially lethal - majority die,viable,sterile,small body,neuroanatomy defective,partially lethal,lethal,visible,decreased cell death,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,planar polarity defective" "ovary,axon & dorsal cluster neuron,lamina,eye photoreceptor cell,neuron,NMJ bouton,wing margin bristle,ectopic,RP2 motor neuron,embryonic epidermis,dorsal,dorsal denticle,wing,eye photoreceptor cell | P-stage,lymph gland derived hemocyte | third instar larval stage,embryonic/larval lymph gland | third instar larval stage,crystal cell | third instar larval stage,wing & macrochaeta69B,macrochaeta,wing sensillum,bouton,neuromuscular junctionC57,postsynaptic membraneC57,mitochondrion & boutonC57,t-bar,interfollicle cell,supernumerary,heat sensitive,chaeta | ectopic & wingbbg-C96,denticle row 1,wing margin,eye,ommatidium,morphogenetic furrow,presumptive embryonic salivary gland,neuromuscular junction | third instar larval stageMhc.PU,dorsal cluster neuron | adult stage,medulla | adult stage" DRSC10087 IE -2.47348023 0.15174713 1.560219484 0.298005816 -0.215672261 0.128005045 FBgn0264695 Mhc Myosin heavy chain http://flybase.org/reports/FBgn0264695 protein_coding_gene "motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR002928, InterPro:IPR004009 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR004009 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity actin-dependent ATPase activity ; GO:0030898 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay structural constituent of muscle ; GO:0008307 | inferred from mutant phenotype" "muscle contraction ; GO:0006936 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype skeletal muscle myosin thick filament assembly ; GO:0030241 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype muscle thin filament assembly ; GO:0071689 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype muscle cell differentiation ; GO:0042692 | inferred from mutant phenotype myosin filament organization ; GO:0031033 | inferred from mutant phenotype" "myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR002928, InterPro:IPR004009 polytene chromosome puff ; GO:0005703 | inferred from direct assay A band ; GO:0031672 | inferred from direct assay sarcomere ; GO:0030017 | inferred from direct assay myosin complex ; GO:0016459 | inferred from sequence or structural similarity" "mhc, Mhc, MHC, CG17927, Ifm(2)RU1, ifm(2)RU2, MyHC, FBgn0002741, Myo, DmMHC, Dm II, ifm(2)2, DROMHC, DroMII, mMHC, Mhc36B, sMHC, l(2)k10423, Bsh, Ifm(2)2, Sht, l(2)M66, l(2)36Ae, Stp, Nup, MRP, Mrp, ifm(2)RU1, chr2L:16765388..16765564, chr2L:16781880..16782040, Myo6" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site, IPR001609:Myosin head, motor domain, IPR002928:Myosin tail, IPR004009:Myosin, N-terminal, SH3-like" CG17927 11-Aug-17 DroID_v2017_08 "Drer\myhb, Drer\myha, Drer\LOC100329748, Drer\myo5ab, Drer\myh7bb, Drer\myo18aa, Drer\myh14, Drer\myh6, Drer\smyhc2, Drer\smyhc1, Drer\myh11a, Drer\LOC100537963, Drer\smyhc3, Drer\si:dkey-110c1.10, Drer\myhz2, Drer\myh9a, Drer\LOC100333206, Drer\myhc4, Drer\LOC103909185, Drer\myh7ba, Drer\LOC100333572, Drer\myhz1.2, Drer\myhz1.1, Drer\ns:zf-e68, Drer\myh10, Drer\wu:fd14a01, Drer\myh9b, Drer\LOC100329813, Drer\cgnl1, Drer\myh11b, Drer\vmhc, Drer\myo18ab, Drer\myo5c, Drer\LOC100331349, Drer\vmhcl, Drer\myo5aa, Drer\myo5b" "Scer\MYO2, Scer\MYO4, Scer\MYO1" "Cele\myo-5, Cele\hum-2, Cele\unc-15, Cele\myo-6, Cele\nmy-2, Cele\myo-1, Cele\myo-3, Cele\unc-54, Cele\nmy-1, Cele\myo-2, Cele\hum-9" "Xtro\myh13, Xtro\myh9, Xtro\myh6, Xtro\myo18b, Xtro\myh4, Xtro\myh2, Xtro\LOC100485637, Xtro\myo5b, Xtro\myh15, Xtro\myh8, Xtro\myh11, Xtro\myh3, Xtro\myo5a" "Mmus\Myh3, Mmus\Myo18b, Mmus\Myh7, Mmus\Cdk5rap2, Mmus\Myh10, Mmus\Myo5b, Mmus\Myh9, Mmus\Myo5a, Mmus\Myh2, Mmus\Myh14, Mmus\Myh11, Mmus\Myh13, Mmus\Myh8, Mmus\Myh4, Mmus\Myh6, Mmus\Pde4dip, Mmus\Myo18a, Mmus\Myo5c, Mmus\Myh15, Mmus\Myh1, Mmus\Cgnl1, Mmus\Myh7b" "Hsap\MYH1, Hsap\MYO5B, Hsap\MYH7, Hsap\CDK5RAP2, Hsap\MYH11, Hsap\MYH6, Hsap\MYH7B, Hsap\MYH9, Hsap\CGNL1, Hsap\MYO5A, Hsap\MYH3, Hsap\MYH10, Hsap\MYH4, Hsap\MYH14, Hsap\MYH15, Hsap\MYH2, Hsap\MYO18B, Hsap\PDE4DIP, Hsap\MYO18A, Hsap\MYH13, Hsap\MYH8, Hsap\MYO5C" " embryonic stage | late && larval stage , pupal stage | late , adult stage , embryonic stage , adult stage | male , embryonic stage | stage 16 , pharate adult stage && adult stage , larval stage " " organism

, skeletal muscle of abdomen

, mesothoracic extracoxal depressor muscle 66

, proboscis muscle

, adult abdomen

, adult thorax

, adult esophageal muscle

, skeletal muscle of leg

, somatic muscle

, testis

, somatic muscle

{ e N* } , adult head

, visceral muscle

, indirect flight muscle

, basalar muscle 51

, intracoxal depressor muscle

, larval muscle system

, mesothoracic pleurosternal muscle

, larval somatic muscle

{ e Dl* } , skeletal muscle of head

, somatic mesoderm

, basalar muscle 52

, intracoxal levator muscle

, skeletal muscle of thorax

" adult stage | male testis

DRSC03367 E 0.507275638 0.380817739 1.78275102 -2.488034787 -0.731386506 1.074970336 FBgn0015919 caup caupolican http://flybase.org/reports/FBgn0015919 FBgn0014195 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with ara transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from sequence or structural similarity with ara" phagocytosis ; GO:0006909 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from genetic interaction with ara negative regulation of growth ; GO:0045926 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from genetic interaction with CycE inferred from physical interaction with CycE positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with ara equator specification ; GO:0045317 | traceable author statement muscle cell fate commitment ; GO:0042693 | inferred from genetic interaction with ara nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:8632 "caup, Iro-C, IRO-C, iro, iro-C, CG10605, Iro, Caup, IroC" "IPR001356:Homeobox domain, IPR003893:Iroquois-class homeodomain protein, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR008422:Homeobox KN domain" CG10605 11-Aug-17 DroID_v2017_08 "Drer\irx7, Drer\irx5b, Drer\irx6a, Drer\pknox2, Drer\meis3, Drer\irx3a, Drer\meis2b, Drer\irx1b, Drer\irx4b, Drer\tgif1, Drer\pknox1.1, Drer\irx4a, Drer\irx2a, Drer\pknox1.2, Drer\irx1a, Drer\meis1a, Drer\irx5a, Drer\irx3b, Drer\meis2a, Drer\mkxa" "Scer\TOS8, Scer\CUP9, Scer\HMLALPHA2, Scer\HMRA2, Scer\MATALPHA2" Cele\irx-1 "Xtro\meis1, Xtro\irx3, Xtro\pknox2, Xtro\meis2, Xtro\irx4, Xtro\meis3, Xtro\tgif2, Xtro\irx1, Xtro\mkx, Xtro\tgif1, Xtro\irx2, Xtro\irx5" "Mmus\Irx5, Mmus\Meis2, Mmus\Meis3, Mmus\Mkx, Mmus\Pknox1, Mmus\Irx6, Mmus\Irx2, Mmus\Irx3, Mmus\Tgif2lx1, Mmus\Tgif2, Mmus\Irx1, Mmus\Tgif1, Mmus\Tgif2lx2, Mmus\Pknox2, Mmus\Meis1, Mmus\Irx4" "Hsap\IRX4, Hsap\IRX2, Hsap\PKNOX2, Hsap\MEIS1, Hsap\IRX1, Hsap\TGIF2, Hsap\IRX3, Hsap\TGIF1, Hsap\IRX5, Hsap\TGIF2LY, Hsap\TGIF2LX, Hsap\PKNOX1, Hsap\TGIF2-C20orf24, Hsap\MKX, Hsap\IRX6, Hsap\MEIS2" " larval stage | third instar , adult stage , embryonic stage | late , larval stage , embryonic stage -- adult stage , larval stage | second instar , embryonic stage | stage >=11 " " wing vein L5

, alula

, embryonic/larval proventriculus

, procephalic segment

, ventral nerve cord

, tegula

, wing vein L1

, wing vein L3

, mesothoracic pleurum

, imaginal disc

, dorsal metathoracic disc

, epidermis | lateral

" "visible,lethal,recessive,viable,female sterile,male sterile,planar polarity defective" "macrochaeta,microchaeta,mesothoracic segment,notopleural suture,scutellum,wing,macrochaeta & scutum,eye,vertical bristle,scutum & microchaeta | medial-537.4,ectopic,ommatidium,dorsal margin photoreceptor" FBgn0000611 exd extradenticle http://flybase.org/reports/FBgn0000611 "FBgn0010248, FBgn0025242" protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from physical interaction with lab transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with hth enhancer binding ; GO:0035326 | inferred from physical interaction with dpp transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from physical interaction with hth transcription coactivator activity ; GO:0003713 | inferred from direct assay activating transcription factor binding ; GO:0033613 | inferred from physical interaction with Dfd sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O46339 transcription factor binding ; GO:0008134 | inferred from physical interaction with hth protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P83949 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with lab" "eye development ; GO:0001654 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype protein import into nucleus, translocation ; GO:0000060 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype salivary gland boundary specification ; GO:0007432 | traceable author statement brain development ; GO:0007420 | inferred from mutant phenotype oenocyte development ; GO:0007438 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay regulation of cell fate specification ; GO:0042659 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype salivary gland boundary specification ; GO:0007432 | non-traceable author statement" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement transcription factor complex ; GO:0005667 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with abd-A inferred from physical interaction with hth "Exd, Dm-EXD, DExd, EXD, Dpbx, td48, l(1)IV, anon-EST:fe1H3, Pbx1, CG8933, exd, lincRNA.S9404" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR005542:PBX, IPR009057:Homeobox domain-like" CG8933 11-Aug-17 DroID_v2017_08 "Drer\LOC100537845, Drer\pbx1a, Drer\pbx3a, Drer\pbx3b, Drer\pbx4, Drer\pbx1b, Drer\pbx2" "Scer\HMRA2, Scer\HMLALPHA2, Scer\CUP9, Scer\TOS8, Scer\MATALPHA2" "Cele\ceh-60, Cele\ceh-40, Cele\ceh-20, Cele\F31E3.2" "Xtro\pbx3, Xtro\pbx2, Xtro\pbx1" "Mmus\Pbx4, Mmus\Pbx2, Mmus\Pbx3, Mmus\Pbx1" "Hsap\PBX2, Hsap\PBX3, Hsap\PBX4, Hsap\PBX1" " embryonic stage , embryonic stage | stage >11 , embryonic stage | stage 12 " " somatic mesoderm

{ + BX-C- } , embryonic central nervous system

,

gradient , abdomen

, visceral mesoderm | gradient

" "lethal,recessive,visible,somatic clone,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,pair rule phenotype,partially lethal - majority die,size defective" "adult abdominal segment 7,somatic clone,female genitalia,adult abdominal segment 6,arista,leg,proximal,leg sensillum,ectopic,male genitalia,adult abdominal segment 8,adult abdominal segment 9,adult head,cuticle,metathoracic ventral denticle belt,mesothoracic ventral denticle belt,prothoracic ventral denticle belt,prothoracic dorsal trichome,hypostomal sclerite,embryonic mesothoracic segment,ventral,embryonic metathoracic segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,mesothoracic tergum & macrochaeta | ectopic | somatic clone,scutellum & chaeta | somatic clone,embryonic/larval oenocyte,neuroblast NB6-4 of abdomen,neuroblast NB6-4 of thorax,trochanter,femur,dorsal,posterior,embryonic head,embryonic thorax,embryonic gnathal segment,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,presumptive embryonic/larval peripheral nervous system,head segment,mandibular segment,dental sclerite,epipharyngeal sclerite,median tooth,lateral process,scutum,distal,eye,medial,metathoracic laterotergite,antenna,head,abdominal tergite 1,abdominal tergite 2,abdominal tergite 3,abdominal tergite 4,abdominal sternite 2,abdominal sternite 3,abdominal sternite 4,abdominal sternite 5,macrochaeta & scutum,third segment of antenna,proboscis,adult abdominal segment 1,adult abdominal segment 2,adult abdominal segment 3,adult abdominal segment 4,deutero/tritocerebral embryonic fiber tract founder cluster,subesophageal embryonic fiber tract founder cluster,supraesophageal embryonic fiber tract founder cluster,cervical connective,tritocerebral commissure,Bolwig nerve,Bolwig organ,embryonic/larval salivary gland,embryonic stomatogastric nervous system,optic lobe,precursor,embryonic abdominal segment,mesothoracic segment,metathoracic segment,abdominal segment 1,tarsal segment,unguis,ventral thoracic disc,tibia,mesothoracic tergum,flight muscle,extracoxal depressor muscle" FBgn0027598 cindr CIN85 and CD2AP related http://flybase.org/reports/FBgn0027598 "FBgn0039803, FBgn0051012" protein_coding_gene cell adhesion molecule binding ; GO:0050839 | inferred from physical interaction with rst inferred from physical interaction with hbs SH3 domain binding ; GO:0017124 | inferred from direct assay compound eye development ; GO:0048749 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype intercellular bridge organization ; GO:0043063 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype positive regulation of receptor-mediated endocytosis ; GO:0048260 | inferred from genetic interaction with mim regulation of cytokinesis ; GO:0032465 | inferred from mutant phenotype cleavage furrow ; GO:0032154 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay intercellular bridge ; GO:0045171 | inferred from direct assay "CG11316, BcDNA:GH03163, CG1408, cindr, CD2AP, Cindr, CG31012" IPR001452:SH3 domain CG31012 11-Aug-17 DroID_v2017_08 "Drer\sh3d21, Drer\nostrin, Drer\cd2ap, Drer\si:dkey-71d15.2, Drer\sh3kbp1" - "Cele\Y44E3A.4, Cele\C36E8.4" "Xtro\cd2ap, Xtro\sh3kbp1, Xtro\sh3pxd2a" "Mmus\Nostrin, Mmus\Sh3pxd2a, Mmus\Sh3d21, Mmus\Cd2ap, Mmus\Sh3kbp1" "Hsap\SH3KBP1, Hsap\SH3D21, Hsap\CD2AP, Hsap\SH3PXD2A, Hsap\NOSTRIN" "planar polarity defective,lethal,viable,visible" "primary pigment cell,actin cytoskeletonGMR.PF, cindrdsRNA.PC.PD.UAS,inter-ommatidial precursor cell,cone cell,ommatidium,pigment cell,somatic clone,follicle cell,intercellular bridgeGR1, cindrdsRNA.PC.PD.UAS,border follicle cell,actin cytoskeletonGMR.PF, cindrdsRNA.UAS,secondary pigment cell,tertiary pigment cell,eye | pupal stage,macrochaeta,intercellular bridgeGR1, cindrdsRNA.UAS,chaeta,supernumerary" FBgn0264822 CR44030 - http://flybase.org/reports/FBgn0264822 non_protein_coding_gene - - - CR44030 - CR44030 11-Aug-17 DroID_v2017_08 - - - - - -